data_8R2P
# 
_entry.id   8R2P 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R2P         pdb_00008r2p 10.2210/pdb8r2p/pdb 
WWPDB D_1292134529 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R2P 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-07 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        'another linker' 
_pdbx_database_related.db_id          8CPL 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              johan.nilvebrant@kth.se 
_pdbx_contact_author.name_first         Johan 
_pdbx_contact_author.name_last          Nilvebrant 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6104-6446 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Moche, M.'      1 0000-0002-4834-7076 
'Friberg, O.'    2 0009-0002-8533-3906 
'Nygren, P.A.'   3 0000-0003-4214-6991 
'Nilvebrant, J.' 4 0000-0002-6104-6446 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Engineered imaging scaffolds for cryo-EM of small proteins of interest.' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Moche, M.'      1 0000-0002-4834-7076 
primary 'Nygren, P.A.'   2 0000-0003-4214-6991 
primary 'Nilvebrant, J.' 3 0000-0002-6104-6446 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Putrescine aminotransferase,Immunoglobulin G-binding protein A' 57054.121 4    2.6.1.82,2.6.1.29 G487A ? 
;The polypeptide chain consists of P42588_7-457 and P38507_160-269 connected by a linker. P38507 is mutated at Gly240Ala corresponding to residue 487 in the model.,The polypeptide chain consists of P42588_7-457 and P38507_160-269 connected by a linker. P38507 is mutated at Gly240Ala corresponding to residue 487 in the model.
;
2 non-polymer syn "PYRIDOXAL-5'-PHOSPHATE"                                         247.142   4    ?                 ?     ? ? 
3 water       nat water                                                            18.015    1507 ?                 ?     ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;PAT,PATase,Cadaverine transaminase,Diamine transaminase,Putrescine transaminase,Putrescine--2-oxoglutaric acid transaminase,Putrescine:2-OG aminotransferase,IgG-binding protein A,Staphylococcal protein A,SpA
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GSSHHHHHHYYLESASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSL
NTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTES
VEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVA
AVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATI
ATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAI
EFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEALEVSAKEQQNAFYE
ILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQAPK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSSHHHHHHYYLESASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSL
NTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTES
VEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVA
AVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATI
ATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAI
EFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEALEVSAKEQQNAFYE
ILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQAPK
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 "PYRIDOXAL-5'-PHOSPHATE" PLP 
3 water                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   SER n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  TYR n 
1 11  TYR n 
1 12  LEU n 
1 13  GLU n 
1 14  SER n 
1 15  ALA n 
1 16  SER n 
1 17  ALA n 
1 18  LEU n 
1 19  ALA n 
1 20  CYS n 
1 21  SER n 
1 22  ALA n 
1 23  HIS n 
1 24  ALA n 
1 25  LEU n 
1 26  ASN n 
1 27  LEU n 
1 28  ILE n 
1 29  GLU n 
1 30  LYS n 
1 31  ARG n 
1 32  THR n 
1 33  LEU n 
1 34  ASP n 
1 35  HIS n 
1 36  GLU n 
1 37  GLU n 
1 38  MET n 
1 39  LYS n 
1 40  ALA n 
1 41  LEU n 
1 42  ASN n 
1 43  ARG n 
1 44  GLU n 
1 45  VAL n 
1 46  ILE n 
1 47  GLU n 
1 48  TYR n 
1 49  PHE n 
1 50  LYS n 
1 51  GLU n 
1 52  HIS n 
1 53  VAL n 
1 54  ASN n 
1 55  PRO n 
1 56  GLY n 
1 57  PHE n 
1 58  LEU n 
1 59  GLU n 
1 60  TYR n 
1 61  ARG n 
1 62  LYS n 
1 63  SER n 
1 64  VAL n 
1 65  THR n 
1 66  ALA n 
1 67  GLY n 
1 68  GLY n 
1 69  ASP n 
1 70  TYR n 
1 71  GLY n 
1 72  ALA n 
1 73  VAL n 
1 74  GLU n 
1 75  TRP n 
1 76  GLN n 
1 77  ALA n 
1 78  GLY n 
1 79  SER n 
1 80  LEU n 
1 81  ASN n 
1 82  THR n 
1 83  LEU n 
1 84  VAL n 
1 85  ASP n 
1 86  THR n 
1 87  GLN n 
1 88  GLY n 
1 89  GLN n 
1 90  GLU n 
1 91  PHE n 
1 92  ILE n 
1 93  ASP n 
1 94  CYS n 
1 95  LEU n 
1 96  GLY n 
1 97  GLY n 
1 98  PHE n 
1 99  GLY n 
1 100 ILE n 
1 101 PHE n 
1 102 ASN n 
1 103 VAL n 
1 104 GLY n 
1 105 HIS n 
1 106 ARG n 
1 107 ASN n 
1 108 PRO n 
1 109 VAL n 
1 110 VAL n 
1 111 VAL n 
1 112 SER n 
1 113 ALA n 
1 114 VAL n 
1 115 GLN n 
1 116 ASN n 
1 117 GLN n 
1 118 LEU n 
1 119 ALA n 
1 120 LYS n 
1 121 GLN n 
1 122 PRO n 
1 123 LEU n 
1 124 HIS n 
1 125 SER n 
1 126 GLN n 
1 127 GLU n 
1 128 LEU n 
1 129 LEU n 
1 130 ASP n 
1 131 PRO n 
1 132 LEU n 
1 133 ARG n 
1 134 ALA n 
1 135 MET n 
1 136 LEU n 
1 137 ALA n 
1 138 LYS n 
1 139 THR n 
1 140 LEU n 
1 141 ALA n 
1 142 ALA n 
1 143 LEU n 
1 144 THR n 
1 145 PRO n 
1 146 GLY n 
1 147 LYS n 
1 148 LEU n 
1 149 LYS n 
1 150 TYR n 
1 151 SER n 
1 152 PHE n 
1 153 PHE n 
1 154 CYS n 
1 155 ASN n 
1 156 SER n 
1 157 GLY n 
1 158 THR n 
1 159 GLU n 
1 160 SER n 
1 161 VAL n 
1 162 GLU n 
1 163 ALA n 
1 164 ALA n 
1 165 LEU n 
1 166 LYS n 
1 167 LEU n 
1 168 ALA n 
1 169 LYS n 
1 170 ALA n 
1 171 TYR n 
1 172 GLN n 
1 173 SER n 
1 174 PRO n 
1 175 ARG n 
1 176 GLY n 
1 177 LYS n 
1 178 PHE n 
1 179 THR n 
1 180 PHE n 
1 181 ILE n 
1 182 ALA n 
1 183 THR n 
1 184 SER n 
1 185 GLY n 
1 186 ALA n 
1 187 PHE n 
1 188 HIS n 
1 189 GLY n 
1 190 LYS n 
1 191 SER n 
1 192 LEU n 
1 193 GLY n 
1 194 ALA n 
1 195 LEU n 
1 196 SER n 
1 197 ALA n 
1 198 THR n 
1 199 ALA n 
1 200 LYS n 
1 201 SER n 
1 202 THR n 
1 203 PHE n 
1 204 ARG n 
1 205 LYS n 
1 206 PRO n 
1 207 PHE n 
1 208 MET n 
1 209 PRO n 
1 210 LEU n 
1 211 LEU n 
1 212 PRO n 
1 213 GLY n 
1 214 PHE n 
1 215 ARG n 
1 216 HIS n 
1 217 VAL n 
1 218 PRO n 
1 219 PHE n 
1 220 GLY n 
1 221 ASN n 
1 222 ILE n 
1 223 GLU n 
1 224 ALA n 
1 225 MET n 
1 226 ARG n 
1 227 THR n 
1 228 ALA n 
1 229 LEU n 
1 230 ASN n 
1 231 GLU n 
1 232 CYS n 
1 233 LYS n 
1 234 LYS n 
1 235 THR n 
1 236 GLY n 
1 237 ASP n 
1 238 ASP n 
1 239 VAL n 
1 240 ALA n 
1 241 ALA n 
1 242 VAL n 
1 243 ILE n 
1 244 LEU n 
1 245 GLU n 
1 246 PRO n 
1 247 ILE n 
1 248 GLN n 
1 249 GLY n 
1 250 GLU n 
1 251 GLY n 
1 252 GLY n 
1 253 VAL n 
1 254 ILE n 
1 255 LEU n 
1 256 PRO n 
1 257 PRO n 
1 258 PRO n 
1 259 GLY n 
1 260 TYR n 
1 261 LEU n 
1 262 THR n 
1 263 ALA n 
1 264 VAL n 
1 265 ARG n 
1 266 LYS n 
1 267 LEU n 
1 268 CYS n 
1 269 ASP n 
1 270 GLU n 
1 271 PHE n 
1 272 GLY n 
1 273 ALA n 
1 274 LEU n 
1 275 MET n 
1 276 ILE n 
1 277 LEU n 
1 278 ASP n 
1 279 GLU n 
1 280 VAL n 
1 281 GLN n 
1 282 THR n 
1 283 GLY n 
1 284 MET n 
1 285 GLY n 
1 286 ARG n 
1 287 THR n 
1 288 GLY n 
1 289 LYS n 
1 290 MET n 
1 291 PHE n 
1 292 ALA n 
1 293 CYS n 
1 294 GLU n 
1 295 HIS n 
1 296 GLU n 
1 297 ASN n 
1 298 VAL n 
1 299 GLN n 
1 300 PRO n 
1 301 ASP n 
1 302 ILE n 
1 303 LEU n 
1 304 CYS n 
1 305 LEU n 
1 306 ALA n 
1 307 LYS n 
1 308 ALA n 
1 309 LEU n 
1 310 GLY n 
1 311 GLY n 
1 312 GLY n 
1 313 VAL n 
1 314 MET n 
1 315 PRO n 
1 316 ILE n 
1 317 GLY n 
1 318 ALA n 
1 319 THR n 
1 320 ILE n 
1 321 ALA n 
1 322 THR n 
1 323 GLU n 
1 324 GLU n 
1 325 VAL n 
1 326 PHE n 
1 327 SER n 
1 328 VAL n 
1 329 LEU n 
1 330 PHE n 
1 331 ASP n 
1 332 ASN n 
1 333 PRO n 
1 334 PHE n 
1 335 LEU n 
1 336 HIS n 
1 337 THR n 
1 338 THR n 
1 339 THR n 
1 340 PHE n 
1 341 GLY n 
1 342 GLY n 
1 343 ASN n 
1 344 PRO n 
1 345 LEU n 
1 346 ALA n 
1 347 CYS n 
1 348 ALA n 
1 349 ALA n 
1 350 ALA n 
1 351 LEU n 
1 352 ALA n 
1 353 THR n 
1 354 ILE n 
1 355 ASN n 
1 356 VAL n 
1 357 LEU n 
1 358 LEU n 
1 359 GLU n 
1 360 GLN n 
1 361 ASN n 
1 362 LEU n 
1 363 PRO n 
1 364 ALA n 
1 365 GLN n 
1 366 ALA n 
1 367 GLU n 
1 368 GLN n 
1 369 LYS n 
1 370 GLY n 
1 371 ASP n 
1 372 MET n 
1 373 LEU n 
1 374 LEU n 
1 375 ASP n 
1 376 GLY n 
1 377 PHE n 
1 378 ARG n 
1 379 GLN n 
1 380 LEU n 
1 381 ALA n 
1 382 ARG n 
1 383 GLU n 
1 384 TYR n 
1 385 PRO n 
1 386 ASP n 
1 387 LEU n 
1 388 VAL n 
1 389 GLN n 
1 390 GLU n 
1 391 ALA n 
1 392 ARG n 
1 393 GLY n 
1 394 LYS n 
1 395 GLY n 
1 396 MET n 
1 397 LEU n 
1 398 MET n 
1 399 ALA n 
1 400 ILE n 
1 401 GLU n 
1 402 PHE n 
1 403 VAL n 
1 404 ASP n 
1 405 ASN n 
1 406 GLU n 
1 407 ILE n 
1 408 GLY n 
1 409 TYR n 
1 410 ASN n 
1 411 PHE n 
1 412 ALA n 
1 413 SER n 
1 414 GLU n 
1 415 MET n 
1 416 PHE n 
1 417 ARG n 
1 418 GLN n 
1 419 ARG n 
1 420 VAL n 
1 421 LEU n 
1 422 VAL n 
1 423 ALA n 
1 424 GLY n 
1 425 THR n 
1 426 LEU n 
1 427 ASN n 
1 428 ASN n 
1 429 ALA n 
1 430 LYS n 
1 431 THR n 
1 432 ILE n 
1 433 ARG n 
1 434 ILE n 
1 435 GLU n 
1 436 PRO n 
1 437 PRO n 
1 438 LEU n 
1 439 THR n 
1 440 LEU n 
1 441 THR n 
1 442 ILE n 
1 443 GLU n 
1 444 GLN n 
1 445 CYS n 
1 446 GLU n 
1 447 LEU n 
1 448 VAL n 
1 449 ILE n 
1 450 LYS n 
1 451 ALA n 
1 452 ALA n 
1 453 ARG n 
1 454 LYS n 
1 455 ALA n 
1 456 LEU n 
1 457 ALA n 
1 458 ALA n 
1 459 MET n 
1 460 ARG n 
1 461 VAL n 
1 462 SER n 
1 463 VAL n 
1 464 GLU n 
1 465 GLU n 
1 466 ALA n 
1 467 LEU n 
1 468 GLU n 
1 469 VAL n 
1 470 SER n 
1 471 ALA n 
1 472 LYS n 
1 473 GLU n 
1 474 GLN n 
1 475 GLN n 
1 476 ASN n 
1 477 ALA n 
1 478 PHE n 
1 479 TYR n 
1 480 GLU n 
1 481 ILE n 
1 482 LEU n 
1 483 HIS n 
1 484 LEU n 
1 485 PRO n 
1 486 ASN n 
1 487 LEU n 
1 488 ASN n 
1 489 GLU n 
1 490 GLU n 
1 491 GLN n 
1 492 ARG n 
1 493 ASN n 
1 494 ALA n 
1 495 PHE n 
1 496 ILE n 
1 497 GLN n 
1 498 SER n 
1 499 LEU n 
1 500 LYS n 
1 501 ASP n 
1 502 ASP n 
1 503 PRO n 
1 504 SER n 
1 505 GLN n 
1 506 SER n 
1 507 ALA n 
1 508 ASN n 
1 509 LEU n 
1 510 LEU n 
1 511 ALA n 
1 512 GLU n 
1 513 ALA n 
1 514 LYS n 
1 515 LYS n 
1 516 LEU n 
1 517 ASN n 
1 518 ASP n 
1 519 ALA n 
1 520 GLN n 
1 521 ALA n 
1 522 PRO n 
1 523 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   464 ? ? 'patA, ygjG, b3073, JW5510' ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 465 523 ? ? spa                         ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                  ?                      'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                 ?                      'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE               ?                      'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'          ?                      'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                 ?                      'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                ?                      'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'          ?                      'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                  ?                      'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                ?                      'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                    ?                      'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE               ?                      'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                  ?                      'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                   ?                      'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE               ?                      'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE            ?                      'C9 H11 N O2'    165.189 
PLP non-polymer         . "PYRIDOXAL-5'-PHOSPHATE" 'VITAMIN B6 Phosphate' 'C8 H10 N O6 P'  247.142 
PRO 'L-peptide linking' y PROLINE                  ?                      'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                   ?                      'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                ?                      'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN               ?                      'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                 ?                      'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                   ?                      'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -6  ?   ?   ?   A . n 
A 1 2   SER 2   -5  ?   ?   ?   A . n 
A 1 3   SER 3   -4  ?   ?   ?   A . n 
A 1 4   HIS 4   -3  ?   ?   ?   A . n 
A 1 5   HIS 5   -2  ?   ?   ?   A . n 
A 1 6   HIS 6   -1  ?   ?   ?   A . n 
A 1 7   HIS 7   0   ?   ?   ?   A . n 
A 1 8   HIS 8   1   ?   ?   ?   A . n 
A 1 9   HIS 9   2   ?   ?   ?   A . n 
A 1 10  TYR 10  3   ?   ?   ?   A . n 
A 1 11  TYR 11  4   ?   ?   ?   A . n 
A 1 12  LEU 12  5   ?   ?   ?   A . n 
A 1 13  GLU 13  6   ?   ?   ?   A . n 
A 1 14  SER 14  7   ?   ?   ?   A . n 
A 1 15  ALA 15  8   8   ALA ALA A . n 
A 1 16  SER 16  9   9   SER SER A . n 
A 1 17  ALA 17  10  10  ALA ALA A . n 
A 1 18  LEU 18  11  11  LEU LEU A . n 
A 1 19  ALA 19  12  12  ALA ALA A . n 
A 1 20  CYS 20  13  13  CYS CYS A . n 
A 1 21  SER 21  14  14  SER SER A . n 
A 1 22  ALA 22  15  15  ALA ALA A . n 
A 1 23  HIS 23  16  16  HIS HIS A . n 
A 1 24  ALA 24  17  17  ALA ALA A . n 
A 1 25  LEU 25  18  18  LEU LEU A . n 
A 1 26  ASN 26  19  19  ASN ASN A . n 
A 1 27  LEU 27  20  20  LEU LEU A . n 
A 1 28  ILE 28  21  21  ILE ILE A . n 
A 1 29  GLU 29  22  22  GLU GLU A . n 
A 1 30  LYS 30  23  23  LYS LYS A . n 
A 1 31  ARG 31  24  24  ARG ARG A . n 
A 1 32  THR 32  25  25  THR THR A . n 
A 1 33  LEU 33  26  26  LEU LEU A . n 
A 1 34  ASP 34  27  27  ASP ASP A . n 
A 1 35  HIS 35  28  28  HIS HIS A . n 
A 1 36  GLU 36  29  29  GLU GLU A . n 
A 1 37  GLU 37  30  30  GLU GLU A . n 
A 1 38  MET 38  31  31  MET MET A . n 
A 1 39  LYS 39  32  32  LYS LYS A . n 
A 1 40  ALA 40  33  33  ALA ALA A . n 
A 1 41  LEU 41  34  34  LEU LEU A . n 
A 1 42  ASN 42  35  35  ASN ASN A . n 
A 1 43  ARG 43  36  36  ARG ARG A . n 
A 1 44  GLU 44  37  37  GLU GLU A . n 
A 1 45  VAL 45  38  38  VAL VAL A . n 
A 1 46  ILE 46  39  39  ILE ILE A . n 
A 1 47  GLU 47  40  40  GLU GLU A . n 
A 1 48  TYR 48  41  41  TYR TYR A . n 
A 1 49  PHE 49  42  42  PHE PHE A . n 
A 1 50  LYS 50  43  43  LYS LYS A . n 
A 1 51  GLU 51  44  44  GLU GLU A . n 
A 1 52  HIS 52  45  45  HIS HIS A . n 
A 1 53  VAL 53  46  46  VAL VAL A . n 
A 1 54  ASN 54  47  47  ASN ASN A . n 
A 1 55  PRO 55  48  48  PRO PRO A . n 
A 1 56  GLY 56  49  49  GLY GLY A . n 
A 1 57  PHE 57  50  50  PHE PHE A . n 
A 1 58  LEU 58  51  51  LEU LEU A . n 
A 1 59  GLU 59  52  52  GLU GLU A . n 
A 1 60  TYR 60  53  53  TYR TYR A . n 
A 1 61  ARG 61  54  54  ARG ARG A . n 
A 1 62  LYS 62  55  55  LYS LYS A . n 
A 1 63  SER 63  56  56  SER SER A . n 
A 1 64  VAL 64  57  57  VAL VAL A . n 
A 1 65  THR 65  58  58  THR THR A . n 
A 1 66  ALA 66  59  59  ALA ALA A . n 
A 1 67  GLY 67  60  60  GLY GLY A . n 
A 1 68  GLY 68  61  61  GLY GLY A . n 
A 1 69  ASP 69  62  62  ASP ASP A . n 
A 1 70  TYR 70  63  63  TYR TYR A . n 
A 1 71  GLY 71  64  64  GLY GLY A . n 
A 1 72  ALA 72  65  65  ALA ALA A . n 
A 1 73  VAL 73  66  66  VAL VAL A . n 
A 1 74  GLU 74  67  67  GLU GLU A . n 
A 1 75  TRP 75  68  68  TRP TRP A . n 
A 1 76  GLN 76  69  69  GLN GLN A . n 
A 1 77  ALA 77  70  70  ALA ALA A . n 
A 1 78  GLY 78  71  71  GLY GLY A . n 
A 1 79  SER 79  72  72  SER SER A . n 
A 1 80  LEU 80  73  73  LEU LEU A . n 
A 1 81  ASN 81  74  74  ASN ASN A . n 
A 1 82  THR 82  75  75  THR THR A . n 
A 1 83  LEU 83  76  76  LEU LEU A . n 
A 1 84  VAL 84  77  77  VAL VAL A . n 
A 1 85  ASP 85  78  78  ASP ASP A . n 
A 1 86  THR 86  79  79  THR THR A . n 
A 1 87  GLN 87  80  80  GLN GLN A . n 
A 1 88  GLY 88  81  81  GLY GLY A . n 
A 1 89  GLN 89  82  82  GLN GLN A . n 
A 1 90  GLU 90  83  83  GLU GLU A . n 
A 1 91  PHE 91  84  84  PHE PHE A . n 
A 1 92  ILE 92  85  85  ILE ILE A . n 
A 1 93  ASP 93  86  86  ASP ASP A . n 
A 1 94  CYS 94  87  87  CYS CYS A . n 
A 1 95  LEU 95  88  88  LEU LEU A . n 
A 1 96  GLY 96  89  89  GLY GLY A . n 
A 1 97  GLY 97  90  90  GLY GLY A . n 
A 1 98  PHE 98  91  91  PHE PHE A . n 
A 1 99  GLY 99  92  92  GLY GLY A . n 
A 1 100 ILE 100 93  93  ILE ILE A . n 
A 1 101 PHE 101 94  94  PHE PHE A . n 
A 1 102 ASN 102 95  95  ASN ASN A . n 
A 1 103 VAL 103 96  96  VAL VAL A . n 
A 1 104 GLY 104 97  97  GLY GLY A . n 
A 1 105 HIS 105 98  98  HIS HIS A . n 
A 1 106 ARG 106 99  99  ARG ARG A . n 
A 1 107 ASN 107 100 100 ASN ASN A . n 
A 1 108 PRO 108 101 101 PRO PRO A . n 
A 1 109 VAL 109 102 102 VAL VAL A . n 
A 1 110 VAL 110 103 103 VAL VAL A . n 
A 1 111 VAL 111 104 104 VAL VAL A . n 
A 1 112 SER 112 105 105 SER SER A . n 
A 1 113 ALA 113 106 106 ALA ALA A . n 
A 1 114 VAL 114 107 107 VAL VAL A . n 
A 1 115 GLN 115 108 108 GLN GLN A . n 
A 1 116 ASN 116 109 109 ASN ASN A . n 
A 1 117 GLN 117 110 110 GLN GLN A . n 
A 1 118 LEU 118 111 111 LEU LEU A . n 
A 1 119 ALA 119 112 112 ALA ALA A . n 
A 1 120 LYS 120 113 113 LYS LYS A . n 
A 1 121 GLN 121 114 114 GLN GLN A . n 
A 1 122 PRO 122 115 115 PRO PRO A . n 
A 1 123 LEU 123 116 116 LEU LEU A . n 
A 1 124 HIS 124 117 117 HIS HIS A . n 
A 1 125 SER 125 118 118 SER SER A . n 
A 1 126 GLN 126 119 119 GLN GLN A . n 
A 1 127 GLU 127 120 120 GLU GLU A . n 
A 1 128 LEU 128 121 121 LEU LEU A . n 
A 1 129 LEU 129 122 122 LEU LEU A . n 
A 1 130 ASP 130 123 123 ASP ASP A . n 
A 1 131 PRO 131 124 124 PRO PRO A . n 
A 1 132 LEU 132 125 125 LEU LEU A . n 
A 1 133 ARG 133 126 126 ARG ARG A . n 
A 1 134 ALA 134 127 127 ALA ALA A . n 
A 1 135 MET 135 128 128 MET MET A . n 
A 1 136 LEU 136 129 129 LEU LEU A . n 
A 1 137 ALA 137 130 130 ALA ALA A . n 
A 1 138 LYS 138 131 131 LYS LYS A . n 
A 1 139 THR 139 132 132 THR THR A . n 
A 1 140 LEU 140 133 133 LEU LEU A . n 
A 1 141 ALA 141 134 134 ALA ALA A . n 
A 1 142 ALA 142 135 135 ALA ALA A . n 
A 1 143 LEU 143 136 136 LEU LEU A . n 
A 1 144 THR 144 137 137 THR THR A . n 
A 1 145 PRO 145 138 138 PRO PRO A . n 
A 1 146 GLY 146 139 139 GLY GLY A . n 
A 1 147 LYS 147 140 140 LYS LYS A . n 
A 1 148 LEU 148 141 141 LEU LEU A . n 
A 1 149 LYS 149 142 142 LYS LYS A . n 
A 1 150 TYR 150 143 143 TYR TYR A . n 
A 1 151 SER 151 144 144 SER SER A . n 
A 1 152 PHE 152 145 145 PHE PHE A . n 
A 1 153 PHE 153 146 146 PHE PHE A . n 
A 1 154 CYS 154 147 147 CYS CYS A . n 
A 1 155 ASN 155 148 148 ASN ASN A . n 
A 1 156 SER 156 149 149 SER SER A . n 
A 1 157 GLY 157 150 150 GLY GLY A . n 
A 1 158 THR 158 151 151 THR THR A . n 
A 1 159 GLU 159 152 152 GLU GLU A . n 
A 1 160 SER 160 153 153 SER SER A . n 
A 1 161 VAL 161 154 154 VAL VAL A . n 
A 1 162 GLU 162 155 155 GLU GLU A . n 
A 1 163 ALA 163 156 156 ALA ALA A . n 
A 1 164 ALA 164 157 157 ALA ALA A . n 
A 1 165 LEU 165 158 158 LEU LEU A . n 
A 1 166 LYS 166 159 159 LYS LYS A . n 
A 1 167 LEU 167 160 160 LEU LEU A . n 
A 1 168 ALA 168 161 161 ALA ALA A . n 
A 1 169 LYS 169 162 162 LYS LYS A . n 
A 1 170 ALA 170 163 163 ALA ALA A . n 
A 1 171 TYR 171 164 164 TYR TYR A . n 
A 1 172 GLN 172 165 165 GLN GLN A . n 
A 1 173 SER 173 166 166 SER SER A . n 
A 1 174 PRO 174 167 167 PRO PRO A . n 
A 1 175 ARG 175 168 168 ARG ARG A . n 
A 1 176 GLY 176 169 169 GLY GLY A . n 
A 1 177 LYS 177 170 170 LYS LYS A . n 
A 1 178 PHE 178 171 171 PHE PHE A . n 
A 1 179 THR 179 172 172 THR THR A . n 
A 1 180 PHE 180 173 173 PHE PHE A . n 
A 1 181 ILE 181 174 174 ILE ILE A . n 
A 1 182 ALA 182 175 175 ALA ALA A . n 
A 1 183 THR 183 176 176 THR THR A . n 
A 1 184 SER 184 177 177 SER SER A . n 
A 1 185 GLY 185 178 178 GLY GLY A . n 
A 1 186 ALA 186 179 179 ALA ALA A . n 
A 1 187 PHE 187 180 180 PHE PHE A . n 
A 1 188 HIS 188 181 181 HIS HIS A . n 
A 1 189 GLY 189 182 182 GLY GLY A . n 
A 1 190 LYS 190 183 183 LYS LYS A . n 
A 1 191 SER 191 184 184 SER SER A . n 
A 1 192 LEU 192 185 185 LEU LEU A . n 
A 1 193 GLY 193 186 186 GLY GLY A . n 
A 1 194 ALA 194 187 187 ALA ALA A . n 
A 1 195 LEU 195 188 188 LEU LEU A . n 
A 1 196 SER 196 189 189 SER SER A . n 
A 1 197 ALA 197 190 190 ALA ALA A . n 
A 1 198 THR 198 191 191 THR THR A . n 
A 1 199 ALA 199 192 192 ALA ALA A . n 
A 1 200 LYS 200 193 193 LYS LYS A . n 
A 1 201 SER 201 194 194 SER SER A . n 
A 1 202 THR 202 195 195 THR THR A . n 
A 1 203 PHE 203 196 196 PHE PHE A . n 
A 1 204 ARG 204 197 197 ARG ARG A . n 
A 1 205 LYS 205 198 198 LYS LYS A . n 
A 1 206 PRO 206 199 199 PRO PRO A . n 
A 1 207 PHE 207 200 200 PHE PHE A . n 
A 1 208 MET 208 201 201 MET MET A . n 
A 1 209 PRO 209 202 202 PRO PRO A . n 
A 1 210 LEU 210 203 203 LEU LEU A . n 
A 1 211 LEU 211 204 204 LEU LEU A . n 
A 1 212 PRO 212 205 205 PRO PRO A . n 
A 1 213 GLY 213 206 206 GLY GLY A . n 
A 1 214 PHE 214 207 207 PHE PHE A . n 
A 1 215 ARG 215 208 208 ARG ARG A . n 
A 1 216 HIS 216 209 209 HIS HIS A . n 
A 1 217 VAL 217 210 210 VAL VAL A . n 
A 1 218 PRO 218 211 211 PRO PRO A . n 
A 1 219 PHE 219 212 212 PHE PHE A . n 
A 1 220 GLY 220 213 213 GLY GLY A . n 
A 1 221 ASN 221 214 214 ASN ASN A . n 
A 1 222 ILE 222 215 215 ILE ILE A . n 
A 1 223 GLU 223 216 216 GLU GLU A . n 
A 1 224 ALA 224 217 217 ALA ALA A . n 
A 1 225 MET 225 218 218 MET MET A . n 
A 1 226 ARG 226 219 219 ARG ARG A . n 
A 1 227 THR 227 220 220 THR THR A . n 
A 1 228 ALA 228 221 221 ALA ALA A . n 
A 1 229 LEU 229 222 222 LEU LEU A . n 
A 1 230 ASN 230 223 223 ASN ASN A . n 
A 1 231 GLU 231 224 224 GLU GLU A . n 
A 1 232 CYS 232 225 225 CYS CYS A . n 
A 1 233 LYS 233 226 226 LYS LYS A . n 
A 1 234 LYS 234 227 227 LYS LYS A . n 
A 1 235 THR 235 228 228 THR THR A . n 
A 1 236 GLY 236 229 229 GLY GLY A . n 
A 1 237 ASP 237 230 230 ASP ASP A . n 
A 1 238 ASP 238 231 231 ASP ASP A . n 
A 1 239 VAL 239 232 232 VAL VAL A . n 
A 1 240 ALA 240 233 233 ALA ALA A . n 
A 1 241 ALA 241 234 234 ALA ALA A . n 
A 1 242 VAL 242 235 235 VAL VAL A . n 
A 1 243 ILE 243 236 236 ILE ILE A . n 
A 1 244 LEU 244 237 237 LEU LEU A . n 
A 1 245 GLU 245 238 238 GLU GLU A . n 
A 1 246 PRO 246 239 239 PRO PRO A . n 
A 1 247 ILE 247 240 240 ILE ILE A . n 
A 1 248 GLN 248 241 241 GLN GLN A . n 
A 1 249 GLY 249 242 242 GLY GLY A . n 
A 1 250 GLU 250 243 243 GLU GLU A . n 
A 1 251 GLY 251 244 244 GLY GLY A . n 
A 1 252 GLY 252 245 245 GLY GLY A . n 
A 1 253 VAL 253 246 246 VAL VAL A . n 
A 1 254 ILE 254 247 247 ILE ILE A . n 
A 1 255 LEU 255 248 248 LEU LEU A . n 
A 1 256 PRO 256 249 249 PRO PRO A . n 
A 1 257 PRO 257 250 250 PRO PRO A . n 
A 1 258 PRO 258 251 251 PRO PRO A . n 
A 1 259 GLY 259 252 252 GLY GLY A . n 
A 1 260 TYR 260 253 253 TYR TYR A . n 
A 1 261 LEU 261 254 254 LEU LEU A . n 
A 1 262 THR 262 255 255 THR THR A . n 
A 1 263 ALA 263 256 256 ALA ALA A . n 
A 1 264 VAL 264 257 257 VAL VAL A . n 
A 1 265 ARG 265 258 258 ARG ARG A . n 
A 1 266 LYS 266 259 259 LYS LYS A . n 
A 1 267 LEU 267 260 260 LEU LEU A . n 
A 1 268 CYS 268 261 261 CYS CYS A . n 
A 1 269 ASP 269 262 262 ASP ASP A . n 
A 1 270 GLU 270 263 263 GLU GLU A . n 
A 1 271 PHE 271 264 264 PHE PHE A . n 
A 1 272 GLY 272 265 265 GLY GLY A . n 
A 1 273 ALA 273 266 266 ALA ALA A . n 
A 1 274 LEU 274 267 267 LEU LEU A . n 
A 1 275 MET 275 268 268 MET MET A . n 
A 1 276 ILE 276 269 269 ILE ILE A . n 
A 1 277 LEU 277 270 270 LEU LEU A . n 
A 1 278 ASP 278 271 271 ASP ASP A . n 
A 1 279 GLU 279 272 272 GLU GLU A . n 
A 1 280 VAL 280 273 273 VAL VAL A . n 
A 1 281 GLN 281 274 274 GLN GLN A . n 
A 1 282 THR 282 275 275 THR THR A . n 
A 1 283 GLY 283 276 276 GLY GLY A . n 
A 1 284 MET 284 277 277 MET MET A . n 
A 1 285 GLY 285 278 278 GLY GLY A . n 
A 1 286 ARG 286 279 279 ARG ARG A . n 
A 1 287 THR 287 280 280 THR THR A . n 
A 1 288 GLY 288 281 281 GLY GLY A . n 
A 1 289 LYS 289 282 282 LYS LYS A . n 
A 1 290 MET 290 283 283 MET MET A . n 
A 1 291 PHE 291 284 284 PHE PHE A . n 
A 1 292 ALA 292 285 285 ALA ALA A . n 
A 1 293 CYS 293 286 286 CYS CYS A . n 
A 1 294 GLU 294 287 287 GLU GLU A . n 
A 1 295 HIS 295 288 288 HIS HIS A . n 
A 1 296 GLU 296 289 289 GLU GLU A . n 
A 1 297 ASN 297 290 290 ASN ASN A . n 
A 1 298 VAL 298 291 291 VAL VAL A . n 
A 1 299 GLN 299 292 292 GLN GLN A . n 
A 1 300 PRO 300 293 293 PRO PRO A . n 
A 1 301 ASP 301 294 294 ASP ASP A . n 
A 1 302 ILE 302 295 295 ILE ILE A . n 
A 1 303 LEU 303 296 296 LEU LEU A . n 
A 1 304 CYS 304 297 297 CYS CYS A . n 
A 1 305 LEU 305 298 298 LEU LEU A . n 
A 1 306 ALA 306 299 299 ALA ALA A . n 
A 1 307 LYS 307 300 300 LYS LYS A . n 
A 1 308 ALA 308 301 301 ALA ALA A . n 
A 1 309 LEU 309 302 302 LEU LEU A . n 
A 1 310 GLY 310 303 303 GLY GLY A . n 
A 1 311 GLY 311 304 304 GLY GLY A . n 
A 1 312 GLY 312 305 305 GLY GLY A . n 
A 1 313 VAL 313 306 306 VAL VAL A . n 
A 1 314 MET 314 307 307 MET MET A . n 
A 1 315 PRO 315 308 308 PRO PRO A . n 
A 1 316 ILE 316 309 309 ILE ILE A . n 
A 1 317 GLY 317 310 310 GLY GLY A . n 
A 1 318 ALA 318 311 311 ALA ALA A . n 
A 1 319 THR 319 312 312 THR THR A . n 
A 1 320 ILE 320 313 313 ILE ILE A . n 
A 1 321 ALA 321 314 314 ALA ALA A . n 
A 1 322 THR 322 315 315 THR THR A . n 
A 1 323 GLU 323 316 316 GLU GLU A . n 
A 1 324 GLU 324 317 317 GLU GLU A . n 
A 1 325 VAL 325 318 318 VAL VAL A . n 
A 1 326 PHE 326 319 319 PHE PHE A . n 
A 1 327 SER 327 320 320 SER SER A . n 
A 1 328 VAL 328 321 321 VAL VAL A . n 
A 1 329 LEU 329 322 322 LEU LEU A . n 
A 1 330 PHE 330 323 323 PHE PHE A . n 
A 1 331 ASP 331 324 324 ASP ASP A . n 
A 1 332 ASN 332 325 325 ASN ASN A . n 
A 1 333 PRO 333 326 326 PRO PRO A . n 
A 1 334 PHE 334 327 327 PHE PHE A . n 
A 1 335 LEU 335 328 328 LEU LEU A . n 
A 1 336 HIS 336 329 329 HIS HIS A . n 
A 1 337 THR 337 330 330 THR THR A . n 
A 1 338 THR 338 331 331 THR THR A . n 
A 1 339 THR 339 332 332 THR THR A . n 
A 1 340 PHE 340 333 333 PHE PHE A . n 
A 1 341 GLY 341 334 334 GLY GLY A . n 
A 1 342 GLY 342 335 335 GLY GLY A . n 
A 1 343 ASN 343 336 336 ASN ASN A . n 
A 1 344 PRO 344 337 337 PRO PRO A . n 
A 1 345 LEU 345 338 338 LEU LEU A . n 
A 1 346 ALA 346 339 339 ALA ALA A . n 
A 1 347 CYS 347 340 340 CYS CYS A . n 
A 1 348 ALA 348 341 341 ALA ALA A . n 
A 1 349 ALA 349 342 342 ALA ALA A . n 
A 1 350 ALA 350 343 343 ALA ALA A . n 
A 1 351 LEU 351 344 344 LEU LEU A . n 
A 1 352 ALA 352 345 345 ALA ALA A . n 
A 1 353 THR 353 346 346 THR THR A . n 
A 1 354 ILE 354 347 347 ILE ILE A . n 
A 1 355 ASN 355 348 348 ASN ASN A . n 
A 1 356 VAL 356 349 349 VAL VAL A . n 
A 1 357 LEU 357 350 350 LEU LEU A . n 
A 1 358 LEU 358 351 351 LEU LEU A . n 
A 1 359 GLU 359 352 352 GLU GLU A . n 
A 1 360 GLN 360 353 353 GLN GLN A . n 
A 1 361 ASN 361 354 354 ASN ASN A . n 
A 1 362 LEU 362 355 355 LEU LEU A . n 
A 1 363 PRO 363 356 356 PRO PRO A . n 
A 1 364 ALA 364 357 357 ALA ALA A . n 
A 1 365 GLN 365 358 358 GLN GLN A . n 
A 1 366 ALA 366 359 359 ALA ALA A . n 
A 1 367 GLU 367 360 360 GLU GLU A . n 
A 1 368 GLN 368 361 361 GLN GLN A . n 
A 1 369 LYS 369 362 362 LYS LYS A . n 
A 1 370 GLY 370 363 363 GLY GLY A . n 
A 1 371 ASP 371 364 364 ASP ASP A . n 
A 1 372 MET 372 365 365 MET MET A . n 
A 1 373 LEU 373 366 366 LEU LEU A . n 
A 1 374 LEU 374 367 367 LEU LEU A . n 
A 1 375 ASP 375 368 368 ASP ASP A . n 
A 1 376 GLY 376 369 369 GLY GLY A . n 
A 1 377 PHE 377 370 370 PHE PHE A . n 
A 1 378 ARG 378 371 371 ARG ARG A . n 
A 1 379 GLN 379 372 372 GLN GLN A . n 
A 1 380 LEU 380 373 373 LEU LEU A . n 
A 1 381 ALA 381 374 374 ALA ALA A . n 
A 1 382 ARG 382 375 375 ARG ARG A . n 
A 1 383 GLU 383 376 376 GLU GLU A . n 
A 1 384 TYR 384 377 377 TYR TYR A . n 
A 1 385 PRO 385 378 378 PRO PRO A . n 
A 1 386 ASP 386 379 379 ASP ASP A . n 
A 1 387 LEU 387 380 380 LEU LEU A . n 
A 1 388 VAL 388 381 381 VAL VAL A . n 
A 1 389 GLN 389 382 382 GLN GLN A . n 
A 1 390 GLU 390 383 383 GLU GLU A . n 
A 1 391 ALA 391 384 384 ALA ALA A . n 
A 1 392 ARG 392 385 385 ARG ARG A . n 
A 1 393 GLY 393 386 386 GLY GLY A . n 
A 1 394 LYS 394 387 387 LYS LYS A . n 
A 1 395 GLY 395 388 388 GLY GLY A . n 
A 1 396 MET 396 389 389 MET MET A . n 
A 1 397 LEU 397 390 390 LEU LEU A . n 
A 1 398 MET 398 391 391 MET MET A . n 
A 1 399 ALA 399 392 392 ALA ALA A . n 
A 1 400 ILE 400 393 393 ILE ILE A . n 
A 1 401 GLU 401 394 394 GLU GLU A . n 
A 1 402 PHE 402 395 395 PHE PHE A . n 
A 1 403 VAL 403 396 396 VAL VAL A . n 
A 1 404 ASP 404 397 397 ASP ASP A . n 
A 1 405 ASN 405 398 398 ASN ASN A . n 
A 1 406 GLU 406 399 399 GLU GLU A . n 
A 1 407 ILE 407 400 400 ILE ILE A . n 
A 1 408 GLY 408 401 401 GLY GLY A . n 
A 1 409 TYR 409 402 402 TYR TYR A . n 
A 1 410 ASN 410 403 403 ASN ASN A . n 
A 1 411 PHE 411 404 404 PHE PHE A . n 
A 1 412 ALA 412 405 405 ALA ALA A . n 
A 1 413 SER 413 406 406 SER SER A . n 
A 1 414 GLU 414 407 407 GLU GLU A . n 
A 1 415 MET 415 408 408 MET MET A . n 
A 1 416 PHE 416 409 409 PHE PHE A . n 
A 1 417 ARG 417 410 410 ARG ARG A . n 
A 1 418 GLN 418 411 411 GLN GLN A . n 
A 1 419 ARG 419 412 412 ARG ARG A . n 
A 1 420 VAL 420 413 413 VAL VAL A . n 
A 1 421 LEU 421 414 414 LEU LEU A . n 
A 1 422 VAL 422 415 415 VAL VAL A . n 
A 1 423 ALA 423 416 416 ALA ALA A . n 
A 1 424 GLY 424 417 417 GLY GLY A . n 
A 1 425 THR 425 418 418 THR THR A . n 
A 1 426 LEU 426 419 419 LEU LEU A . n 
A 1 427 ASN 427 420 420 ASN ASN A . n 
A 1 428 ASN 428 421 421 ASN ASN A . n 
A 1 429 ALA 429 422 422 ALA ALA A . n 
A 1 430 LYS 430 423 423 LYS LYS A . n 
A 1 431 THR 431 424 424 THR THR A . n 
A 1 432 ILE 432 425 425 ILE ILE A . n 
A 1 433 ARG 433 426 426 ARG ARG A . n 
A 1 434 ILE 434 427 427 ILE ILE A . n 
A 1 435 GLU 435 428 428 GLU GLU A . n 
A 1 436 PRO 436 429 429 PRO PRO A . n 
A 1 437 PRO 437 430 430 PRO PRO A . n 
A 1 438 LEU 438 431 431 LEU LEU A . n 
A 1 439 THR 439 432 432 THR THR A . n 
A 1 440 LEU 440 433 433 LEU LEU A . n 
A 1 441 THR 441 434 434 THR THR A . n 
A 1 442 ILE 442 435 435 ILE ILE A . n 
A 1 443 GLU 443 436 436 GLU GLU A . n 
A 1 444 GLN 444 437 437 GLN GLN A . n 
A 1 445 CYS 445 438 438 CYS CYS A . n 
A 1 446 GLU 446 439 439 GLU GLU A . n 
A 1 447 LEU 447 440 440 LEU LEU A . n 
A 1 448 VAL 448 441 441 VAL VAL A . n 
A 1 449 ILE 449 442 442 ILE ILE A . n 
A 1 450 LYS 450 443 443 LYS LYS A . n 
A 1 451 ALA 451 444 444 ALA ALA A . n 
A 1 452 ALA 452 445 445 ALA ALA A . n 
A 1 453 ARG 453 446 446 ARG ARG A . n 
A 1 454 LYS 454 447 447 LYS LYS A . n 
A 1 455 ALA 455 448 448 ALA ALA A . n 
A 1 456 LEU 456 449 449 LEU LEU A . n 
A 1 457 ALA 457 450 450 ALA ALA A . n 
A 1 458 ALA 458 451 451 ALA ALA A . n 
A 1 459 MET 459 452 452 MET MET A . n 
A 1 460 ARG 460 453 453 ARG ARG A . n 
A 1 461 VAL 461 454 454 VAL VAL A . n 
A 1 462 SER 462 455 455 SER SER A . n 
A 1 463 VAL 463 456 456 VAL VAL A . n 
A 1 464 GLU 464 457 457 GLU GLU A . n 
A 1 465 GLU 465 458 458 GLU GLU A . n 
A 1 466 ALA 466 459 459 ALA ALA A . n 
A 1 467 LEU 467 460 460 LEU LEU A . n 
A 1 468 GLU 468 461 ?   ?   ?   A . n 
A 1 469 VAL 469 462 ?   ?   ?   A . n 
A 1 470 SER 470 463 ?   ?   ?   A . n 
A 1 471 ALA 471 464 ?   ?   ?   A . n 
A 1 472 LYS 472 465 ?   ?   ?   A . n 
A 1 473 GLU 473 466 ?   ?   ?   A . n 
A 1 474 GLN 474 467 ?   ?   ?   A . n 
A 1 475 GLN 475 468 ?   ?   ?   A . n 
A 1 476 ASN 476 469 ?   ?   ?   A . n 
A 1 477 ALA 477 470 ?   ?   ?   A . n 
A 1 478 PHE 478 471 ?   ?   ?   A . n 
A 1 479 TYR 479 472 ?   ?   ?   A . n 
A 1 480 GLU 480 473 ?   ?   ?   A . n 
A 1 481 ILE 481 474 ?   ?   ?   A . n 
A 1 482 LEU 482 475 ?   ?   ?   A . n 
A 1 483 HIS 483 476 ?   ?   ?   A . n 
A 1 484 LEU 484 477 ?   ?   ?   A . n 
A 1 485 PRO 485 478 ?   ?   ?   A . n 
A 1 486 ASN 486 479 ?   ?   ?   A . n 
A 1 487 LEU 487 480 ?   ?   ?   A . n 
A 1 488 ASN 488 481 ?   ?   ?   A . n 
A 1 489 GLU 489 482 ?   ?   ?   A . n 
A 1 490 GLU 490 483 ?   ?   ?   A . n 
A 1 491 GLN 491 484 ?   ?   ?   A . n 
A 1 492 ARG 492 485 ?   ?   ?   A . n 
A 1 493 ASN 493 486 ?   ?   ?   A . n 
A 1 494 ALA 494 487 ?   ?   ?   A . n 
A 1 495 PHE 495 488 ?   ?   ?   A . n 
A 1 496 ILE 496 489 ?   ?   ?   A . n 
A 1 497 GLN 497 490 ?   ?   ?   A . n 
A 1 498 SER 498 491 ?   ?   ?   A . n 
A 1 499 LEU 499 492 ?   ?   ?   A . n 
A 1 500 LYS 500 493 ?   ?   ?   A . n 
A 1 501 ASP 501 494 ?   ?   ?   A . n 
A 1 502 ASP 502 495 ?   ?   ?   A . n 
A 1 503 PRO 503 496 ?   ?   ?   A . n 
A 1 504 SER 504 497 ?   ?   ?   A . n 
A 1 505 GLN 505 498 ?   ?   ?   A . n 
A 1 506 SER 506 499 ?   ?   ?   A . n 
A 1 507 ALA 507 500 ?   ?   ?   A . n 
A 1 508 ASN 508 501 ?   ?   ?   A . n 
A 1 509 LEU 509 502 ?   ?   ?   A . n 
A 1 510 LEU 510 503 ?   ?   ?   A . n 
A 1 511 ALA 511 504 ?   ?   ?   A . n 
A 1 512 GLU 512 505 ?   ?   ?   A . n 
A 1 513 ALA 513 506 ?   ?   ?   A . n 
A 1 514 LYS 514 507 ?   ?   ?   A . n 
A 1 515 LYS 515 508 ?   ?   ?   A . n 
A 1 516 LEU 516 509 ?   ?   ?   A . n 
A 1 517 ASN 517 510 ?   ?   ?   A . n 
A 1 518 ASP 518 511 ?   ?   ?   A . n 
A 1 519 ALA 519 512 ?   ?   ?   A . n 
A 1 520 GLN 520 513 ?   ?   ?   A . n 
A 1 521 ALA 521 514 ?   ?   ?   A . n 
A 1 522 PRO 522 515 ?   ?   ?   A . n 
A 1 523 LYS 523 516 ?   ?   ?   A . n 
B 1 1   GLY 1   -6  ?   ?   ?   B . n 
B 1 2   SER 2   -5  ?   ?   ?   B . n 
B 1 3   SER 3   -4  ?   ?   ?   B . n 
B 1 4   HIS 4   -3  ?   ?   ?   B . n 
B 1 5   HIS 5   -2  ?   ?   ?   B . n 
B 1 6   HIS 6   -1  ?   ?   ?   B . n 
B 1 7   HIS 7   0   ?   ?   ?   B . n 
B 1 8   HIS 8   1   ?   ?   ?   B . n 
B 1 9   HIS 9   2   ?   ?   ?   B . n 
B 1 10  TYR 10  3   ?   ?   ?   B . n 
B 1 11  TYR 11  4   ?   ?   ?   B . n 
B 1 12  LEU 12  5   ?   ?   ?   B . n 
B 1 13  GLU 13  6   ?   ?   ?   B . n 
B 1 14  SER 14  7   ?   ?   ?   B . n 
B 1 15  ALA 15  8   8   ALA ALA B . n 
B 1 16  SER 16  9   9   SER SER B . n 
B 1 17  ALA 17  10  10  ALA ALA B . n 
B 1 18  LEU 18  11  11  LEU LEU B . n 
B 1 19  ALA 19  12  12  ALA ALA B . n 
B 1 20  CYS 20  13  13  CYS CYS B . n 
B 1 21  SER 21  14  14  SER SER B . n 
B 1 22  ALA 22  15  15  ALA ALA B . n 
B 1 23  HIS 23  16  16  HIS HIS B . n 
B 1 24  ALA 24  17  17  ALA ALA B . n 
B 1 25  LEU 25  18  18  LEU LEU B . n 
B 1 26  ASN 26  19  19  ASN ASN B . n 
B 1 27  LEU 27  20  20  LEU LEU B . n 
B 1 28  ILE 28  21  21  ILE ILE B . n 
B 1 29  GLU 29  22  22  GLU GLU B . n 
B 1 30  LYS 30  23  23  LYS LYS B . n 
B 1 31  ARG 31  24  24  ARG ARG B . n 
B 1 32  THR 32  25  25  THR THR B . n 
B 1 33  LEU 33  26  26  LEU LEU B . n 
B 1 34  ASP 34  27  27  ASP ASP B . n 
B 1 35  HIS 35  28  28  HIS HIS B . n 
B 1 36  GLU 36  29  29  GLU GLU B . n 
B 1 37  GLU 37  30  30  GLU GLU B . n 
B 1 38  MET 38  31  31  MET MET B . n 
B 1 39  LYS 39  32  32  LYS LYS B . n 
B 1 40  ALA 40  33  33  ALA ALA B . n 
B 1 41  LEU 41  34  34  LEU LEU B . n 
B 1 42  ASN 42  35  35  ASN ASN B . n 
B 1 43  ARG 43  36  36  ARG ARG B . n 
B 1 44  GLU 44  37  37  GLU GLU B . n 
B 1 45  VAL 45  38  38  VAL VAL B . n 
B 1 46  ILE 46  39  39  ILE ILE B . n 
B 1 47  GLU 47  40  40  GLU GLU B . n 
B 1 48  TYR 48  41  41  TYR TYR B . n 
B 1 49  PHE 49  42  42  PHE PHE B . n 
B 1 50  LYS 50  43  43  LYS LYS B . n 
B 1 51  GLU 51  44  44  GLU GLU B . n 
B 1 52  HIS 52  45  45  HIS HIS B . n 
B 1 53  VAL 53  46  46  VAL VAL B . n 
B 1 54  ASN 54  47  47  ASN ASN B . n 
B 1 55  PRO 55  48  48  PRO PRO B . n 
B 1 56  GLY 56  49  49  GLY GLY B . n 
B 1 57  PHE 57  50  50  PHE PHE B . n 
B 1 58  LEU 58  51  51  LEU LEU B . n 
B 1 59  GLU 59  52  52  GLU GLU B . n 
B 1 60  TYR 60  53  53  TYR TYR B . n 
B 1 61  ARG 61  54  54  ARG ARG B . n 
B 1 62  LYS 62  55  55  LYS LYS B . n 
B 1 63  SER 63  56  56  SER SER B . n 
B 1 64  VAL 64  57  57  VAL VAL B . n 
B 1 65  THR 65  58  58  THR THR B . n 
B 1 66  ALA 66  59  59  ALA ALA B . n 
B 1 67  GLY 67  60  60  GLY GLY B . n 
B 1 68  GLY 68  61  61  GLY GLY B . n 
B 1 69  ASP 69  62  62  ASP ASP B . n 
B 1 70  TYR 70  63  63  TYR TYR B . n 
B 1 71  GLY 71  64  64  GLY GLY B . n 
B 1 72  ALA 72  65  65  ALA ALA B . n 
B 1 73  VAL 73  66  66  VAL VAL B . n 
B 1 74  GLU 74  67  67  GLU GLU B . n 
B 1 75  TRP 75  68  68  TRP TRP B . n 
B 1 76  GLN 76  69  69  GLN GLN B . n 
B 1 77  ALA 77  70  70  ALA ALA B . n 
B 1 78  GLY 78  71  71  GLY GLY B . n 
B 1 79  SER 79  72  72  SER SER B . n 
B 1 80  LEU 80  73  73  LEU LEU B . n 
B 1 81  ASN 81  74  74  ASN ASN B . n 
B 1 82  THR 82  75  75  THR THR B . n 
B 1 83  LEU 83  76  76  LEU LEU B . n 
B 1 84  VAL 84  77  77  VAL VAL B . n 
B 1 85  ASP 85  78  78  ASP ASP B . n 
B 1 86  THR 86  79  79  THR THR B . n 
B 1 87  GLN 87  80  80  GLN GLN B . n 
B 1 88  GLY 88  81  81  GLY GLY B . n 
B 1 89  GLN 89  82  82  GLN GLN B . n 
B 1 90  GLU 90  83  83  GLU GLU B . n 
B 1 91  PHE 91  84  84  PHE PHE B . n 
B 1 92  ILE 92  85  85  ILE ILE B . n 
B 1 93  ASP 93  86  86  ASP ASP B . n 
B 1 94  CYS 94  87  87  CYS CYS B . n 
B 1 95  LEU 95  88  88  LEU LEU B . n 
B 1 96  GLY 96  89  89  GLY GLY B . n 
B 1 97  GLY 97  90  90  GLY GLY B . n 
B 1 98  PHE 98  91  91  PHE PHE B . n 
B 1 99  GLY 99  92  92  GLY GLY B . n 
B 1 100 ILE 100 93  93  ILE ILE B . n 
B 1 101 PHE 101 94  94  PHE PHE B . n 
B 1 102 ASN 102 95  95  ASN ASN B . n 
B 1 103 VAL 103 96  96  VAL VAL B . n 
B 1 104 GLY 104 97  97  GLY GLY B . n 
B 1 105 HIS 105 98  98  HIS HIS B . n 
B 1 106 ARG 106 99  99  ARG ARG B . n 
B 1 107 ASN 107 100 100 ASN ASN B . n 
B 1 108 PRO 108 101 101 PRO PRO B . n 
B 1 109 VAL 109 102 102 VAL VAL B . n 
B 1 110 VAL 110 103 103 VAL VAL B . n 
B 1 111 VAL 111 104 104 VAL VAL B . n 
B 1 112 SER 112 105 105 SER SER B . n 
B 1 113 ALA 113 106 106 ALA ALA B . n 
B 1 114 VAL 114 107 107 VAL VAL B . n 
B 1 115 GLN 115 108 108 GLN GLN B . n 
B 1 116 ASN 116 109 109 ASN ASN B . n 
B 1 117 GLN 117 110 110 GLN GLN B . n 
B 1 118 LEU 118 111 111 LEU LEU B . n 
B 1 119 ALA 119 112 112 ALA ALA B . n 
B 1 120 LYS 120 113 113 LYS LYS B . n 
B 1 121 GLN 121 114 114 GLN GLN B . n 
B 1 122 PRO 122 115 115 PRO PRO B . n 
B 1 123 LEU 123 116 116 LEU LEU B . n 
B 1 124 HIS 124 117 117 HIS HIS B . n 
B 1 125 SER 125 118 118 SER SER B . n 
B 1 126 GLN 126 119 119 GLN GLN B . n 
B 1 127 GLU 127 120 120 GLU GLU B . n 
B 1 128 LEU 128 121 121 LEU LEU B . n 
B 1 129 LEU 129 122 122 LEU LEU B . n 
B 1 130 ASP 130 123 123 ASP ASP B . n 
B 1 131 PRO 131 124 124 PRO PRO B . n 
B 1 132 LEU 132 125 125 LEU LEU B . n 
B 1 133 ARG 133 126 126 ARG ARG B . n 
B 1 134 ALA 134 127 127 ALA ALA B . n 
B 1 135 MET 135 128 128 MET MET B . n 
B 1 136 LEU 136 129 129 LEU LEU B . n 
B 1 137 ALA 137 130 130 ALA ALA B . n 
B 1 138 LYS 138 131 131 LYS LYS B . n 
B 1 139 THR 139 132 132 THR THR B . n 
B 1 140 LEU 140 133 133 LEU LEU B . n 
B 1 141 ALA 141 134 134 ALA ALA B . n 
B 1 142 ALA 142 135 135 ALA ALA B . n 
B 1 143 LEU 143 136 136 LEU LEU B . n 
B 1 144 THR 144 137 137 THR THR B . n 
B 1 145 PRO 145 138 138 PRO PRO B . n 
B 1 146 GLY 146 139 139 GLY GLY B . n 
B 1 147 LYS 147 140 140 LYS LYS B . n 
B 1 148 LEU 148 141 141 LEU LEU B . n 
B 1 149 LYS 149 142 142 LYS LYS B . n 
B 1 150 TYR 150 143 143 TYR TYR B . n 
B 1 151 SER 151 144 144 SER SER B . n 
B 1 152 PHE 152 145 145 PHE PHE B . n 
B 1 153 PHE 153 146 146 PHE PHE B . n 
B 1 154 CYS 154 147 147 CYS CYS B . n 
B 1 155 ASN 155 148 148 ASN ASN B . n 
B 1 156 SER 156 149 149 SER SER B . n 
B 1 157 GLY 157 150 150 GLY GLY B . n 
B 1 158 THR 158 151 151 THR THR B . n 
B 1 159 GLU 159 152 152 GLU GLU B . n 
B 1 160 SER 160 153 153 SER SER B . n 
B 1 161 VAL 161 154 154 VAL VAL B . n 
B 1 162 GLU 162 155 155 GLU GLU B . n 
B 1 163 ALA 163 156 156 ALA ALA B . n 
B 1 164 ALA 164 157 157 ALA ALA B . n 
B 1 165 LEU 165 158 158 LEU LEU B . n 
B 1 166 LYS 166 159 159 LYS LYS B . n 
B 1 167 LEU 167 160 160 LEU LEU B . n 
B 1 168 ALA 168 161 161 ALA ALA B . n 
B 1 169 LYS 169 162 162 LYS LYS B . n 
B 1 170 ALA 170 163 163 ALA ALA B . n 
B 1 171 TYR 171 164 164 TYR TYR B . n 
B 1 172 GLN 172 165 165 GLN GLN B . n 
B 1 173 SER 173 166 166 SER SER B . n 
B 1 174 PRO 174 167 167 PRO PRO B . n 
B 1 175 ARG 175 168 168 ARG ARG B . n 
B 1 176 GLY 176 169 169 GLY GLY B . n 
B 1 177 LYS 177 170 170 LYS LYS B . n 
B 1 178 PHE 178 171 171 PHE PHE B . n 
B 1 179 THR 179 172 172 THR THR B . n 
B 1 180 PHE 180 173 173 PHE PHE B . n 
B 1 181 ILE 181 174 174 ILE ILE B . n 
B 1 182 ALA 182 175 175 ALA ALA B . n 
B 1 183 THR 183 176 176 THR THR B . n 
B 1 184 SER 184 177 177 SER SER B . n 
B 1 185 GLY 185 178 178 GLY GLY B . n 
B 1 186 ALA 186 179 179 ALA ALA B . n 
B 1 187 PHE 187 180 180 PHE PHE B . n 
B 1 188 HIS 188 181 181 HIS HIS B . n 
B 1 189 GLY 189 182 182 GLY GLY B . n 
B 1 190 LYS 190 183 183 LYS LYS B . n 
B 1 191 SER 191 184 184 SER SER B . n 
B 1 192 LEU 192 185 185 LEU LEU B . n 
B 1 193 GLY 193 186 186 GLY GLY B . n 
B 1 194 ALA 194 187 187 ALA ALA B . n 
B 1 195 LEU 195 188 188 LEU LEU B . n 
B 1 196 SER 196 189 189 SER SER B . n 
B 1 197 ALA 197 190 190 ALA ALA B . n 
B 1 198 THR 198 191 191 THR THR B . n 
B 1 199 ALA 199 192 192 ALA ALA B . n 
B 1 200 LYS 200 193 193 LYS LYS B . n 
B 1 201 SER 201 194 194 SER SER B . n 
B 1 202 THR 202 195 195 THR THR B . n 
B 1 203 PHE 203 196 196 PHE PHE B . n 
B 1 204 ARG 204 197 197 ARG ARG B . n 
B 1 205 LYS 205 198 198 LYS LYS B . n 
B 1 206 PRO 206 199 199 PRO PRO B . n 
B 1 207 PHE 207 200 200 PHE PHE B . n 
B 1 208 MET 208 201 201 MET MET B . n 
B 1 209 PRO 209 202 202 PRO PRO B . n 
B 1 210 LEU 210 203 203 LEU LEU B . n 
B 1 211 LEU 211 204 204 LEU LEU B . n 
B 1 212 PRO 212 205 205 PRO PRO B . n 
B 1 213 GLY 213 206 206 GLY GLY B . n 
B 1 214 PHE 214 207 207 PHE PHE B . n 
B 1 215 ARG 215 208 208 ARG ARG B . n 
B 1 216 HIS 216 209 209 HIS HIS B . n 
B 1 217 VAL 217 210 210 VAL VAL B . n 
B 1 218 PRO 218 211 211 PRO PRO B . n 
B 1 219 PHE 219 212 212 PHE PHE B . n 
B 1 220 GLY 220 213 213 GLY GLY B . n 
B 1 221 ASN 221 214 214 ASN ASN B . n 
B 1 222 ILE 222 215 215 ILE ILE B . n 
B 1 223 GLU 223 216 216 GLU GLU B . n 
B 1 224 ALA 224 217 217 ALA ALA B . n 
B 1 225 MET 225 218 218 MET MET B . n 
B 1 226 ARG 226 219 219 ARG ARG B . n 
B 1 227 THR 227 220 220 THR THR B . n 
B 1 228 ALA 228 221 221 ALA ALA B . n 
B 1 229 LEU 229 222 222 LEU LEU B . n 
B 1 230 ASN 230 223 223 ASN ASN B . n 
B 1 231 GLU 231 224 224 GLU GLU B . n 
B 1 232 CYS 232 225 225 CYS CYS B . n 
B 1 233 LYS 233 226 226 LYS LYS B . n 
B 1 234 LYS 234 227 227 LYS LYS B . n 
B 1 235 THR 235 228 228 THR THR B . n 
B 1 236 GLY 236 229 229 GLY GLY B . n 
B 1 237 ASP 237 230 230 ASP ASP B . n 
B 1 238 ASP 238 231 231 ASP ASP B . n 
B 1 239 VAL 239 232 232 VAL VAL B . n 
B 1 240 ALA 240 233 233 ALA ALA B . n 
B 1 241 ALA 241 234 234 ALA ALA B . n 
B 1 242 VAL 242 235 235 VAL VAL B . n 
B 1 243 ILE 243 236 236 ILE ILE B . n 
B 1 244 LEU 244 237 237 LEU LEU B . n 
B 1 245 GLU 245 238 238 GLU GLU B . n 
B 1 246 PRO 246 239 239 PRO PRO B . n 
B 1 247 ILE 247 240 240 ILE ILE B . n 
B 1 248 GLN 248 241 241 GLN GLN B . n 
B 1 249 GLY 249 242 242 GLY GLY B . n 
B 1 250 GLU 250 243 243 GLU GLU B . n 
B 1 251 GLY 251 244 244 GLY GLY B . n 
B 1 252 GLY 252 245 245 GLY GLY B . n 
B 1 253 VAL 253 246 246 VAL VAL B . n 
B 1 254 ILE 254 247 247 ILE ILE B . n 
B 1 255 LEU 255 248 248 LEU LEU B . n 
B 1 256 PRO 256 249 249 PRO PRO B . n 
B 1 257 PRO 257 250 250 PRO PRO B . n 
B 1 258 PRO 258 251 251 PRO PRO B . n 
B 1 259 GLY 259 252 252 GLY GLY B . n 
B 1 260 TYR 260 253 253 TYR TYR B . n 
B 1 261 LEU 261 254 254 LEU LEU B . n 
B 1 262 THR 262 255 255 THR THR B . n 
B 1 263 ALA 263 256 256 ALA ALA B . n 
B 1 264 VAL 264 257 257 VAL VAL B . n 
B 1 265 ARG 265 258 258 ARG ARG B . n 
B 1 266 LYS 266 259 259 LYS LYS B . n 
B 1 267 LEU 267 260 260 LEU LEU B . n 
B 1 268 CYS 268 261 261 CYS CYS B . n 
B 1 269 ASP 269 262 262 ASP ASP B . n 
B 1 270 GLU 270 263 263 GLU GLU B . n 
B 1 271 PHE 271 264 264 PHE PHE B . n 
B 1 272 GLY 272 265 265 GLY GLY B . n 
B 1 273 ALA 273 266 266 ALA ALA B . n 
B 1 274 LEU 274 267 267 LEU LEU B . n 
B 1 275 MET 275 268 268 MET MET B . n 
B 1 276 ILE 276 269 269 ILE ILE B . n 
B 1 277 LEU 277 270 270 LEU LEU B . n 
B 1 278 ASP 278 271 271 ASP ASP B . n 
B 1 279 GLU 279 272 272 GLU GLU B . n 
B 1 280 VAL 280 273 273 VAL VAL B . n 
B 1 281 GLN 281 274 274 GLN GLN B . n 
B 1 282 THR 282 275 275 THR THR B . n 
B 1 283 GLY 283 276 276 GLY GLY B . n 
B 1 284 MET 284 277 277 MET MET B . n 
B 1 285 GLY 285 278 278 GLY GLY B . n 
B 1 286 ARG 286 279 279 ARG ARG B . n 
B 1 287 THR 287 280 280 THR THR B . n 
B 1 288 GLY 288 281 281 GLY GLY B . n 
B 1 289 LYS 289 282 282 LYS LYS B . n 
B 1 290 MET 290 283 283 MET MET B . n 
B 1 291 PHE 291 284 284 PHE PHE B . n 
B 1 292 ALA 292 285 285 ALA ALA B . n 
B 1 293 CYS 293 286 286 CYS CYS B . n 
B 1 294 GLU 294 287 287 GLU GLU B . n 
B 1 295 HIS 295 288 288 HIS HIS B . n 
B 1 296 GLU 296 289 289 GLU GLU B . n 
B 1 297 ASN 297 290 290 ASN ASN B . n 
B 1 298 VAL 298 291 291 VAL VAL B . n 
B 1 299 GLN 299 292 292 GLN GLN B . n 
B 1 300 PRO 300 293 293 PRO PRO B . n 
B 1 301 ASP 301 294 294 ASP ASP B . n 
B 1 302 ILE 302 295 295 ILE ILE B . n 
B 1 303 LEU 303 296 296 LEU LEU B . n 
B 1 304 CYS 304 297 297 CYS CYS B . n 
B 1 305 LEU 305 298 298 LEU LEU B . n 
B 1 306 ALA 306 299 299 ALA ALA B . n 
B 1 307 LYS 307 300 300 LYS LYS B . n 
B 1 308 ALA 308 301 301 ALA ALA B . n 
B 1 309 LEU 309 302 302 LEU LEU B . n 
B 1 310 GLY 310 303 303 GLY GLY B . n 
B 1 311 GLY 311 304 304 GLY GLY B . n 
B 1 312 GLY 312 305 305 GLY GLY B . n 
B 1 313 VAL 313 306 306 VAL VAL B . n 
B 1 314 MET 314 307 307 MET MET B . n 
B 1 315 PRO 315 308 308 PRO PRO B . n 
B 1 316 ILE 316 309 309 ILE ILE B . n 
B 1 317 GLY 317 310 310 GLY GLY B . n 
B 1 318 ALA 318 311 311 ALA ALA B . n 
B 1 319 THR 319 312 312 THR THR B . n 
B 1 320 ILE 320 313 313 ILE ILE B . n 
B 1 321 ALA 321 314 314 ALA ALA B . n 
B 1 322 THR 322 315 315 THR THR B . n 
B 1 323 GLU 323 316 316 GLU GLU B . n 
B 1 324 GLU 324 317 317 GLU GLU B . n 
B 1 325 VAL 325 318 318 VAL VAL B . n 
B 1 326 PHE 326 319 319 PHE PHE B . n 
B 1 327 SER 327 320 320 SER SER B . n 
B 1 328 VAL 328 321 321 VAL VAL B . n 
B 1 329 LEU 329 322 322 LEU LEU B . n 
B 1 330 PHE 330 323 323 PHE PHE B . n 
B 1 331 ASP 331 324 324 ASP ASP B . n 
B 1 332 ASN 332 325 325 ASN ASN B . n 
B 1 333 PRO 333 326 326 PRO PRO B . n 
B 1 334 PHE 334 327 327 PHE PHE B . n 
B 1 335 LEU 335 328 328 LEU LEU B . n 
B 1 336 HIS 336 329 329 HIS HIS B . n 
B 1 337 THR 337 330 330 THR THR B . n 
B 1 338 THR 338 331 331 THR THR B . n 
B 1 339 THR 339 332 332 THR THR B . n 
B 1 340 PHE 340 333 333 PHE PHE B . n 
B 1 341 GLY 341 334 334 GLY GLY B . n 
B 1 342 GLY 342 335 335 GLY GLY B . n 
B 1 343 ASN 343 336 336 ASN ASN B . n 
B 1 344 PRO 344 337 337 PRO PRO B . n 
B 1 345 LEU 345 338 338 LEU LEU B . n 
B 1 346 ALA 346 339 339 ALA ALA B . n 
B 1 347 CYS 347 340 340 CYS CYS B . n 
B 1 348 ALA 348 341 341 ALA ALA B . n 
B 1 349 ALA 349 342 342 ALA ALA B . n 
B 1 350 ALA 350 343 343 ALA ALA B . n 
B 1 351 LEU 351 344 344 LEU LEU B . n 
B 1 352 ALA 352 345 345 ALA ALA B . n 
B 1 353 THR 353 346 346 THR THR B . n 
B 1 354 ILE 354 347 347 ILE ILE B . n 
B 1 355 ASN 355 348 348 ASN ASN B . n 
B 1 356 VAL 356 349 349 VAL VAL B . n 
B 1 357 LEU 357 350 350 LEU LEU B . n 
B 1 358 LEU 358 351 351 LEU LEU B . n 
B 1 359 GLU 359 352 352 GLU GLU B . n 
B 1 360 GLN 360 353 353 GLN GLN B . n 
B 1 361 ASN 361 354 354 ASN ASN B . n 
B 1 362 LEU 362 355 355 LEU LEU B . n 
B 1 363 PRO 363 356 356 PRO PRO B . n 
B 1 364 ALA 364 357 357 ALA ALA B . n 
B 1 365 GLN 365 358 358 GLN GLN B . n 
B 1 366 ALA 366 359 359 ALA ALA B . n 
B 1 367 GLU 367 360 360 GLU GLU B . n 
B 1 368 GLN 368 361 361 GLN GLN B . n 
B 1 369 LYS 369 362 362 LYS LYS B . n 
B 1 370 GLY 370 363 363 GLY GLY B . n 
B 1 371 ASP 371 364 364 ASP ASP B . n 
B 1 372 MET 372 365 365 MET MET B . n 
B 1 373 LEU 373 366 366 LEU LEU B . n 
B 1 374 LEU 374 367 367 LEU LEU B . n 
B 1 375 ASP 375 368 368 ASP ASP B . n 
B 1 376 GLY 376 369 369 GLY GLY B . n 
B 1 377 PHE 377 370 370 PHE PHE B . n 
B 1 378 ARG 378 371 371 ARG ARG B . n 
B 1 379 GLN 379 372 372 GLN GLN B . n 
B 1 380 LEU 380 373 373 LEU LEU B . n 
B 1 381 ALA 381 374 374 ALA ALA B . n 
B 1 382 ARG 382 375 375 ARG ARG B . n 
B 1 383 GLU 383 376 376 GLU GLU B . n 
B 1 384 TYR 384 377 377 TYR TYR B . n 
B 1 385 PRO 385 378 378 PRO PRO B . n 
B 1 386 ASP 386 379 379 ASP ASP B . n 
B 1 387 LEU 387 380 380 LEU LEU B . n 
B 1 388 VAL 388 381 381 VAL VAL B . n 
B 1 389 GLN 389 382 382 GLN GLN B . n 
B 1 390 GLU 390 383 383 GLU GLU B . n 
B 1 391 ALA 391 384 384 ALA ALA B . n 
B 1 392 ARG 392 385 385 ARG ARG B . n 
B 1 393 GLY 393 386 386 GLY GLY B . n 
B 1 394 LYS 394 387 387 LYS LYS B . n 
B 1 395 GLY 395 388 388 GLY GLY B . n 
B 1 396 MET 396 389 389 MET MET B . n 
B 1 397 LEU 397 390 390 LEU LEU B . n 
B 1 398 MET 398 391 391 MET MET B . n 
B 1 399 ALA 399 392 392 ALA ALA B . n 
B 1 400 ILE 400 393 393 ILE ILE B . n 
B 1 401 GLU 401 394 394 GLU GLU B . n 
B 1 402 PHE 402 395 395 PHE PHE B . n 
B 1 403 VAL 403 396 396 VAL VAL B . n 
B 1 404 ASP 404 397 397 ASP ASP B . n 
B 1 405 ASN 405 398 398 ASN ASN B . n 
B 1 406 GLU 406 399 399 GLU GLU B . n 
B 1 407 ILE 407 400 400 ILE ILE B . n 
B 1 408 GLY 408 401 401 GLY GLY B . n 
B 1 409 TYR 409 402 402 TYR TYR B . n 
B 1 410 ASN 410 403 403 ASN ASN B . n 
B 1 411 PHE 411 404 404 PHE PHE B . n 
B 1 412 ALA 412 405 405 ALA ALA B . n 
B 1 413 SER 413 406 406 SER SER B . n 
B 1 414 GLU 414 407 407 GLU GLU B . n 
B 1 415 MET 415 408 408 MET MET B . n 
B 1 416 PHE 416 409 409 PHE PHE B . n 
B 1 417 ARG 417 410 410 ARG ARG B . n 
B 1 418 GLN 418 411 411 GLN GLN B . n 
B 1 419 ARG 419 412 412 ARG ARG B . n 
B 1 420 VAL 420 413 413 VAL VAL B . n 
B 1 421 LEU 421 414 414 LEU LEU B . n 
B 1 422 VAL 422 415 415 VAL VAL B . n 
B 1 423 ALA 423 416 416 ALA ALA B . n 
B 1 424 GLY 424 417 417 GLY GLY B . n 
B 1 425 THR 425 418 418 THR THR B . n 
B 1 426 LEU 426 419 419 LEU LEU B . n 
B 1 427 ASN 427 420 420 ASN ASN B . n 
B 1 428 ASN 428 421 421 ASN ASN B . n 
B 1 429 ALA 429 422 422 ALA ALA B . n 
B 1 430 LYS 430 423 423 LYS LYS B . n 
B 1 431 THR 431 424 424 THR THR B . n 
B 1 432 ILE 432 425 425 ILE ILE B . n 
B 1 433 ARG 433 426 426 ARG ARG B . n 
B 1 434 ILE 434 427 427 ILE ILE B . n 
B 1 435 GLU 435 428 428 GLU GLU B . n 
B 1 436 PRO 436 429 429 PRO PRO B . n 
B 1 437 PRO 437 430 430 PRO PRO B . n 
B 1 438 LEU 438 431 431 LEU LEU B . n 
B 1 439 THR 439 432 432 THR THR B . n 
B 1 440 LEU 440 433 433 LEU LEU B . n 
B 1 441 THR 441 434 434 THR THR B . n 
B 1 442 ILE 442 435 435 ILE ILE B . n 
B 1 443 GLU 443 436 436 GLU GLU B . n 
B 1 444 GLN 444 437 437 GLN GLN B . n 
B 1 445 CYS 445 438 438 CYS CYS B . n 
B 1 446 GLU 446 439 439 GLU GLU B . n 
B 1 447 LEU 447 440 440 LEU LEU B . n 
B 1 448 VAL 448 441 441 VAL VAL B . n 
B 1 449 ILE 449 442 442 ILE ILE B . n 
B 1 450 LYS 450 443 443 LYS LYS B . n 
B 1 451 ALA 451 444 444 ALA ALA B . n 
B 1 452 ALA 452 445 445 ALA ALA B . n 
B 1 453 ARG 453 446 446 ARG ARG B . n 
B 1 454 LYS 454 447 447 LYS LYS B . n 
B 1 455 ALA 455 448 448 ALA ALA B . n 
B 1 456 LEU 456 449 449 LEU LEU B . n 
B 1 457 ALA 457 450 450 ALA ALA B . n 
B 1 458 ALA 458 451 451 ALA ALA B . n 
B 1 459 MET 459 452 452 MET MET B . n 
B 1 460 ARG 460 453 453 ARG ARG B . n 
B 1 461 VAL 461 454 454 VAL VAL B . n 
B 1 462 SER 462 455 455 SER SER B . n 
B 1 463 VAL 463 456 456 VAL VAL B . n 
B 1 464 GLU 464 457 457 GLU GLU B . n 
B 1 465 GLU 465 458 458 GLU GLU B . n 
B 1 466 ALA 466 459 459 ALA ALA B . n 
B 1 467 LEU 467 460 460 LEU LEU B . n 
B 1 468 GLU 468 461 461 GLU GLU B . n 
B 1 469 VAL 469 462 462 VAL VAL B . n 
B 1 470 SER 470 463 463 SER SER B . n 
B 1 471 ALA 471 464 464 ALA ALA B . n 
B 1 472 LYS 472 465 465 LYS LYS B . n 
B 1 473 GLU 473 466 466 GLU GLU B . n 
B 1 474 GLN 474 467 467 GLN GLN B . n 
B 1 475 GLN 475 468 468 GLN GLN B . n 
B 1 476 ASN 476 469 469 ASN ASN B . n 
B 1 477 ALA 477 470 470 ALA ALA B . n 
B 1 478 PHE 478 471 ?   ?   ?   B . n 
B 1 479 TYR 479 472 ?   ?   ?   B . n 
B 1 480 GLU 480 473 ?   ?   ?   B . n 
B 1 481 ILE 481 474 ?   ?   ?   B . n 
B 1 482 LEU 482 475 ?   ?   ?   B . n 
B 1 483 HIS 483 476 ?   ?   ?   B . n 
B 1 484 LEU 484 477 ?   ?   ?   B . n 
B 1 485 PRO 485 478 ?   ?   ?   B . n 
B 1 486 ASN 486 479 ?   ?   ?   B . n 
B 1 487 LEU 487 480 ?   ?   ?   B . n 
B 1 488 ASN 488 481 ?   ?   ?   B . n 
B 1 489 GLU 489 482 ?   ?   ?   B . n 
B 1 490 GLU 490 483 ?   ?   ?   B . n 
B 1 491 GLN 491 484 ?   ?   ?   B . n 
B 1 492 ARG 492 485 ?   ?   ?   B . n 
B 1 493 ASN 493 486 ?   ?   ?   B . n 
B 1 494 ALA 494 487 ?   ?   ?   B . n 
B 1 495 PHE 495 488 ?   ?   ?   B . n 
B 1 496 ILE 496 489 ?   ?   ?   B . n 
B 1 497 GLN 497 490 ?   ?   ?   B . n 
B 1 498 SER 498 491 ?   ?   ?   B . n 
B 1 499 LEU 499 492 ?   ?   ?   B . n 
B 1 500 LYS 500 493 ?   ?   ?   B . n 
B 1 501 ASP 501 494 ?   ?   ?   B . n 
B 1 502 ASP 502 495 ?   ?   ?   B . n 
B 1 503 PRO 503 496 ?   ?   ?   B . n 
B 1 504 SER 504 497 ?   ?   ?   B . n 
B 1 505 GLN 505 498 ?   ?   ?   B . n 
B 1 506 SER 506 499 ?   ?   ?   B . n 
B 1 507 ALA 507 500 ?   ?   ?   B . n 
B 1 508 ASN 508 501 ?   ?   ?   B . n 
B 1 509 LEU 509 502 ?   ?   ?   B . n 
B 1 510 LEU 510 503 ?   ?   ?   B . n 
B 1 511 ALA 511 504 ?   ?   ?   B . n 
B 1 512 GLU 512 505 ?   ?   ?   B . n 
B 1 513 ALA 513 506 ?   ?   ?   B . n 
B 1 514 LYS 514 507 ?   ?   ?   B . n 
B 1 515 LYS 515 508 ?   ?   ?   B . n 
B 1 516 LEU 516 509 ?   ?   ?   B . n 
B 1 517 ASN 517 510 ?   ?   ?   B . n 
B 1 518 ASP 518 511 ?   ?   ?   B . n 
B 1 519 ALA 519 512 ?   ?   ?   B . n 
B 1 520 GLN 520 513 ?   ?   ?   B . n 
B 1 521 ALA 521 514 ?   ?   ?   B . n 
B 1 522 PRO 522 515 ?   ?   ?   B . n 
B 1 523 LYS 523 516 ?   ?   ?   B . n 
C 1 1   GLY 1   -6  ?   ?   ?   C . n 
C 1 2   SER 2   -5  ?   ?   ?   C . n 
C 1 3   SER 3   -4  ?   ?   ?   C . n 
C 1 4   HIS 4   -3  ?   ?   ?   C . n 
C 1 5   HIS 5   -2  ?   ?   ?   C . n 
C 1 6   HIS 6   -1  ?   ?   ?   C . n 
C 1 7   HIS 7   0   ?   ?   ?   C . n 
C 1 8   HIS 8   1   ?   ?   ?   C . n 
C 1 9   HIS 9   2   ?   ?   ?   C . n 
C 1 10  TYR 10  3   ?   ?   ?   C . n 
C 1 11  TYR 11  4   ?   ?   ?   C . n 
C 1 12  LEU 12  5   ?   ?   ?   C . n 
C 1 13  GLU 13  6   ?   ?   ?   C . n 
C 1 14  SER 14  7   ?   ?   ?   C . n 
C 1 15  ALA 15  8   8   ALA ALA C . n 
C 1 16  SER 16  9   9   SER SER C . n 
C 1 17  ALA 17  10  10  ALA ALA C . n 
C 1 18  LEU 18  11  11  LEU LEU C . n 
C 1 19  ALA 19  12  12  ALA ALA C . n 
C 1 20  CYS 20  13  13  CYS CYS C . n 
C 1 21  SER 21  14  14  SER SER C . n 
C 1 22  ALA 22  15  15  ALA ALA C . n 
C 1 23  HIS 23  16  16  HIS HIS C . n 
C 1 24  ALA 24  17  17  ALA ALA C . n 
C 1 25  LEU 25  18  18  LEU LEU C . n 
C 1 26  ASN 26  19  19  ASN ASN C . n 
C 1 27  LEU 27  20  20  LEU LEU C . n 
C 1 28  ILE 28  21  21  ILE ILE C . n 
C 1 29  GLU 29  22  22  GLU GLU C . n 
C 1 30  LYS 30  23  23  LYS LYS C . n 
C 1 31  ARG 31  24  24  ARG ARG C . n 
C 1 32  THR 32  25  25  THR THR C . n 
C 1 33  LEU 33  26  26  LEU LEU C . n 
C 1 34  ASP 34  27  27  ASP ASP C . n 
C 1 35  HIS 35  28  28  HIS HIS C . n 
C 1 36  GLU 36  29  29  GLU GLU C . n 
C 1 37  GLU 37  30  30  GLU GLU C . n 
C 1 38  MET 38  31  31  MET MET C . n 
C 1 39  LYS 39  32  32  LYS LYS C . n 
C 1 40  ALA 40  33  33  ALA ALA C . n 
C 1 41  LEU 41  34  34  LEU LEU C . n 
C 1 42  ASN 42  35  35  ASN ASN C . n 
C 1 43  ARG 43  36  36  ARG ARG C . n 
C 1 44  GLU 44  37  37  GLU GLU C . n 
C 1 45  VAL 45  38  38  VAL VAL C . n 
C 1 46  ILE 46  39  39  ILE ILE C . n 
C 1 47  GLU 47  40  40  GLU GLU C . n 
C 1 48  TYR 48  41  41  TYR TYR C . n 
C 1 49  PHE 49  42  42  PHE PHE C . n 
C 1 50  LYS 50  43  43  LYS LYS C . n 
C 1 51  GLU 51  44  44  GLU GLU C . n 
C 1 52  HIS 52  45  45  HIS HIS C . n 
C 1 53  VAL 53  46  46  VAL VAL C . n 
C 1 54  ASN 54  47  47  ASN ASN C . n 
C 1 55  PRO 55  48  48  PRO PRO C . n 
C 1 56  GLY 56  49  49  GLY GLY C . n 
C 1 57  PHE 57  50  50  PHE PHE C . n 
C 1 58  LEU 58  51  51  LEU LEU C . n 
C 1 59  GLU 59  52  52  GLU GLU C . n 
C 1 60  TYR 60  53  53  TYR TYR C . n 
C 1 61  ARG 61  54  54  ARG ARG C . n 
C 1 62  LYS 62  55  55  LYS LYS C . n 
C 1 63  SER 63  56  56  SER SER C . n 
C 1 64  VAL 64  57  57  VAL VAL C . n 
C 1 65  THR 65  58  58  THR THR C . n 
C 1 66  ALA 66  59  59  ALA ALA C . n 
C 1 67  GLY 67  60  60  GLY GLY C . n 
C 1 68  GLY 68  61  61  GLY GLY C . n 
C 1 69  ASP 69  62  62  ASP ASP C . n 
C 1 70  TYR 70  63  63  TYR TYR C . n 
C 1 71  GLY 71  64  64  GLY GLY C . n 
C 1 72  ALA 72  65  65  ALA ALA C . n 
C 1 73  VAL 73  66  66  VAL VAL C . n 
C 1 74  GLU 74  67  67  GLU GLU C . n 
C 1 75  TRP 75  68  68  TRP TRP C . n 
C 1 76  GLN 76  69  69  GLN GLN C . n 
C 1 77  ALA 77  70  70  ALA ALA C . n 
C 1 78  GLY 78  71  71  GLY GLY C . n 
C 1 79  SER 79  72  72  SER SER C . n 
C 1 80  LEU 80  73  73  LEU LEU C . n 
C 1 81  ASN 81  74  74  ASN ASN C . n 
C 1 82  THR 82  75  75  THR THR C . n 
C 1 83  LEU 83  76  76  LEU LEU C . n 
C 1 84  VAL 84  77  77  VAL VAL C . n 
C 1 85  ASP 85  78  78  ASP ASP C . n 
C 1 86  THR 86  79  79  THR THR C . n 
C 1 87  GLN 87  80  80  GLN GLN C . n 
C 1 88  GLY 88  81  81  GLY GLY C . n 
C 1 89  GLN 89  82  82  GLN GLN C . n 
C 1 90  GLU 90  83  83  GLU GLU C . n 
C 1 91  PHE 91  84  84  PHE PHE C . n 
C 1 92  ILE 92  85  85  ILE ILE C . n 
C 1 93  ASP 93  86  86  ASP ASP C . n 
C 1 94  CYS 94  87  87  CYS CYS C . n 
C 1 95  LEU 95  88  88  LEU LEU C . n 
C 1 96  GLY 96  89  89  GLY GLY C . n 
C 1 97  GLY 97  90  90  GLY GLY C . n 
C 1 98  PHE 98  91  91  PHE PHE C . n 
C 1 99  GLY 99  92  92  GLY GLY C . n 
C 1 100 ILE 100 93  93  ILE ILE C . n 
C 1 101 PHE 101 94  94  PHE PHE C . n 
C 1 102 ASN 102 95  95  ASN ASN C . n 
C 1 103 VAL 103 96  96  VAL VAL C . n 
C 1 104 GLY 104 97  97  GLY GLY C . n 
C 1 105 HIS 105 98  98  HIS HIS C . n 
C 1 106 ARG 106 99  99  ARG ARG C . n 
C 1 107 ASN 107 100 100 ASN ASN C . n 
C 1 108 PRO 108 101 101 PRO PRO C . n 
C 1 109 VAL 109 102 102 VAL VAL C . n 
C 1 110 VAL 110 103 103 VAL VAL C . n 
C 1 111 VAL 111 104 104 VAL VAL C . n 
C 1 112 SER 112 105 105 SER SER C . n 
C 1 113 ALA 113 106 106 ALA ALA C . n 
C 1 114 VAL 114 107 107 VAL VAL C . n 
C 1 115 GLN 115 108 108 GLN GLN C . n 
C 1 116 ASN 116 109 109 ASN ASN C . n 
C 1 117 GLN 117 110 110 GLN GLN C . n 
C 1 118 LEU 118 111 111 LEU LEU C . n 
C 1 119 ALA 119 112 112 ALA ALA C . n 
C 1 120 LYS 120 113 113 LYS LYS C . n 
C 1 121 GLN 121 114 114 GLN GLN C . n 
C 1 122 PRO 122 115 115 PRO PRO C . n 
C 1 123 LEU 123 116 116 LEU LEU C . n 
C 1 124 HIS 124 117 117 HIS HIS C . n 
C 1 125 SER 125 118 118 SER SER C . n 
C 1 126 GLN 126 119 119 GLN GLN C . n 
C 1 127 GLU 127 120 120 GLU GLU C . n 
C 1 128 LEU 128 121 121 LEU LEU C . n 
C 1 129 LEU 129 122 122 LEU LEU C . n 
C 1 130 ASP 130 123 123 ASP ASP C . n 
C 1 131 PRO 131 124 124 PRO PRO C . n 
C 1 132 LEU 132 125 125 LEU LEU C . n 
C 1 133 ARG 133 126 126 ARG ARG C . n 
C 1 134 ALA 134 127 127 ALA ALA C . n 
C 1 135 MET 135 128 128 MET MET C . n 
C 1 136 LEU 136 129 129 LEU LEU C . n 
C 1 137 ALA 137 130 130 ALA ALA C . n 
C 1 138 LYS 138 131 131 LYS LYS C . n 
C 1 139 THR 139 132 132 THR THR C . n 
C 1 140 LEU 140 133 133 LEU LEU C . n 
C 1 141 ALA 141 134 134 ALA ALA C . n 
C 1 142 ALA 142 135 135 ALA ALA C . n 
C 1 143 LEU 143 136 136 LEU LEU C . n 
C 1 144 THR 144 137 137 THR THR C . n 
C 1 145 PRO 145 138 138 PRO PRO C . n 
C 1 146 GLY 146 139 139 GLY GLY C . n 
C 1 147 LYS 147 140 140 LYS LYS C . n 
C 1 148 LEU 148 141 141 LEU LEU C . n 
C 1 149 LYS 149 142 142 LYS LYS C . n 
C 1 150 TYR 150 143 143 TYR TYR C . n 
C 1 151 SER 151 144 144 SER SER C . n 
C 1 152 PHE 152 145 145 PHE PHE C . n 
C 1 153 PHE 153 146 146 PHE PHE C . n 
C 1 154 CYS 154 147 147 CYS CYS C . n 
C 1 155 ASN 155 148 148 ASN ASN C . n 
C 1 156 SER 156 149 149 SER SER C . n 
C 1 157 GLY 157 150 150 GLY GLY C . n 
C 1 158 THR 158 151 151 THR THR C . n 
C 1 159 GLU 159 152 152 GLU GLU C . n 
C 1 160 SER 160 153 153 SER SER C . n 
C 1 161 VAL 161 154 154 VAL VAL C . n 
C 1 162 GLU 162 155 155 GLU GLU C . n 
C 1 163 ALA 163 156 156 ALA ALA C . n 
C 1 164 ALA 164 157 157 ALA ALA C . n 
C 1 165 LEU 165 158 158 LEU LEU C . n 
C 1 166 LYS 166 159 159 LYS LYS C . n 
C 1 167 LEU 167 160 160 LEU LEU C . n 
C 1 168 ALA 168 161 161 ALA ALA C . n 
C 1 169 LYS 169 162 162 LYS LYS C . n 
C 1 170 ALA 170 163 163 ALA ALA C . n 
C 1 171 TYR 171 164 164 TYR TYR C . n 
C 1 172 GLN 172 165 165 GLN GLN C . n 
C 1 173 SER 173 166 166 SER SER C . n 
C 1 174 PRO 174 167 167 PRO PRO C . n 
C 1 175 ARG 175 168 168 ARG ARG C . n 
C 1 176 GLY 176 169 169 GLY GLY C . n 
C 1 177 LYS 177 170 170 LYS LYS C . n 
C 1 178 PHE 178 171 171 PHE PHE C . n 
C 1 179 THR 179 172 172 THR THR C . n 
C 1 180 PHE 180 173 173 PHE PHE C . n 
C 1 181 ILE 181 174 174 ILE ILE C . n 
C 1 182 ALA 182 175 175 ALA ALA C . n 
C 1 183 THR 183 176 176 THR THR C . n 
C 1 184 SER 184 177 177 SER SER C . n 
C 1 185 GLY 185 178 178 GLY GLY C . n 
C 1 186 ALA 186 179 179 ALA ALA C . n 
C 1 187 PHE 187 180 180 PHE PHE C . n 
C 1 188 HIS 188 181 181 HIS HIS C . n 
C 1 189 GLY 189 182 182 GLY GLY C . n 
C 1 190 LYS 190 183 183 LYS LYS C . n 
C 1 191 SER 191 184 184 SER SER C . n 
C 1 192 LEU 192 185 185 LEU LEU C . n 
C 1 193 GLY 193 186 186 GLY GLY C . n 
C 1 194 ALA 194 187 187 ALA ALA C . n 
C 1 195 LEU 195 188 188 LEU LEU C . n 
C 1 196 SER 196 189 189 SER SER C . n 
C 1 197 ALA 197 190 190 ALA ALA C . n 
C 1 198 THR 198 191 191 THR THR C . n 
C 1 199 ALA 199 192 192 ALA ALA C . n 
C 1 200 LYS 200 193 193 LYS LYS C . n 
C 1 201 SER 201 194 194 SER SER C . n 
C 1 202 THR 202 195 195 THR THR C . n 
C 1 203 PHE 203 196 196 PHE PHE C . n 
C 1 204 ARG 204 197 197 ARG ARG C . n 
C 1 205 LYS 205 198 198 LYS LYS C . n 
C 1 206 PRO 206 199 199 PRO PRO C . n 
C 1 207 PHE 207 200 200 PHE PHE C . n 
C 1 208 MET 208 201 201 MET MET C . n 
C 1 209 PRO 209 202 202 PRO PRO C . n 
C 1 210 LEU 210 203 203 LEU LEU C . n 
C 1 211 LEU 211 204 204 LEU LEU C . n 
C 1 212 PRO 212 205 205 PRO PRO C . n 
C 1 213 GLY 213 206 206 GLY GLY C . n 
C 1 214 PHE 214 207 207 PHE PHE C . n 
C 1 215 ARG 215 208 208 ARG ARG C . n 
C 1 216 HIS 216 209 209 HIS HIS C . n 
C 1 217 VAL 217 210 210 VAL VAL C . n 
C 1 218 PRO 218 211 211 PRO PRO C . n 
C 1 219 PHE 219 212 212 PHE PHE C . n 
C 1 220 GLY 220 213 213 GLY GLY C . n 
C 1 221 ASN 221 214 214 ASN ASN C . n 
C 1 222 ILE 222 215 215 ILE ILE C . n 
C 1 223 GLU 223 216 216 GLU GLU C . n 
C 1 224 ALA 224 217 217 ALA ALA C . n 
C 1 225 MET 225 218 218 MET MET C . n 
C 1 226 ARG 226 219 219 ARG ARG C . n 
C 1 227 THR 227 220 220 THR THR C . n 
C 1 228 ALA 228 221 221 ALA ALA C . n 
C 1 229 LEU 229 222 222 LEU LEU C . n 
C 1 230 ASN 230 223 223 ASN ASN C . n 
C 1 231 GLU 231 224 224 GLU GLU C . n 
C 1 232 CYS 232 225 225 CYS CYS C . n 
C 1 233 LYS 233 226 226 LYS LYS C . n 
C 1 234 LYS 234 227 227 LYS LYS C . n 
C 1 235 THR 235 228 228 THR THR C . n 
C 1 236 GLY 236 229 229 GLY GLY C . n 
C 1 237 ASP 237 230 230 ASP ASP C . n 
C 1 238 ASP 238 231 231 ASP ASP C . n 
C 1 239 VAL 239 232 232 VAL VAL C . n 
C 1 240 ALA 240 233 233 ALA ALA C . n 
C 1 241 ALA 241 234 234 ALA ALA C . n 
C 1 242 VAL 242 235 235 VAL VAL C . n 
C 1 243 ILE 243 236 236 ILE ILE C . n 
C 1 244 LEU 244 237 237 LEU LEU C . n 
C 1 245 GLU 245 238 238 GLU GLU C . n 
C 1 246 PRO 246 239 239 PRO PRO C . n 
C 1 247 ILE 247 240 240 ILE ILE C . n 
C 1 248 GLN 248 241 241 GLN GLN C . n 
C 1 249 GLY 249 242 242 GLY GLY C . n 
C 1 250 GLU 250 243 243 GLU GLU C . n 
C 1 251 GLY 251 244 244 GLY GLY C . n 
C 1 252 GLY 252 245 245 GLY GLY C . n 
C 1 253 VAL 253 246 246 VAL VAL C . n 
C 1 254 ILE 254 247 247 ILE ILE C . n 
C 1 255 LEU 255 248 248 LEU LEU C . n 
C 1 256 PRO 256 249 249 PRO PRO C . n 
C 1 257 PRO 257 250 250 PRO PRO C . n 
C 1 258 PRO 258 251 251 PRO PRO C . n 
C 1 259 GLY 259 252 252 GLY GLY C . n 
C 1 260 TYR 260 253 253 TYR TYR C . n 
C 1 261 LEU 261 254 254 LEU LEU C . n 
C 1 262 THR 262 255 255 THR THR C . n 
C 1 263 ALA 263 256 256 ALA ALA C . n 
C 1 264 VAL 264 257 257 VAL VAL C . n 
C 1 265 ARG 265 258 258 ARG ARG C . n 
C 1 266 LYS 266 259 259 LYS LYS C . n 
C 1 267 LEU 267 260 260 LEU LEU C . n 
C 1 268 CYS 268 261 261 CYS CYS C . n 
C 1 269 ASP 269 262 262 ASP ASP C . n 
C 1 270 GLU 270 263 263 GLU GLU C . n 
C 1 271 PHE 271 264 264 PHE PHE C . n 
C 1 272 GLY 272 265 265 GLY GLY C . n 
C 1 273 ALA 273 266 266 ALA ALA C . n 
C 1 274 LEU 274 267 267 LEU LEU C . n 
C 1 275 MET 275 268 268 MET MET C . n 
C 1 276 ILE 276 269 269 ILE ILE C . n 
C 1 277 LEU 277 270 270 LEU LEU C . n 
C 1 278 ASP 278 271 271 ASP ASP C . n 
C 1 279 GLU 279 272 272 GLU GLU C . n 
C 1 280 VAL 280 273 273 VAL VAL C . n 
C 1 281 GLN 281 274 274 GLN GLN C . n 
C 1 282 THR 282 275 275 THR THR C . n 
C 1 283 GLY 283 276 276 GLY GLY C . n 
C 1 284 MET 284 277 277 MET MET C . n 
C 1 285 GLY 285 278 278 GLY GLY C . n 
C 1 286 ARG 286 279 279 ARG ARG C . n 
C 1 287 THR 287 280 280 THR THR C . n 
C 1 288 GLY 288 281 281 GLY GLY C . n 
C 1 289 LYS 289 282 282 LYS LYS C . n 
C 1 290 MET 290 283 283 MET MET C . n 
C 1 291 PHE 291 284 284 PHE PHE C . n 
C 1 292 ALA 292 285 285 ALA ALA C . n 
C 1 293 CYS 293 286 286 CYS CYS C . n 
C 1 294 GLU 294 287 287 GLU GLU C . n 
C 1 295 HIS 295 288 288 HIS HIS C . n 
C 1 296 GLU 296 289 289 GLU GLU C . n 
C 1 297 ASN 297 290 290 ASN ASN C . n 
C 1 298 VAL 298 291 291 VAL VAL C . n 
C 1 299 GLN 299 292 292 GLN GLN C . n 
C 1 300 PRO 300 293 293 PRO PRO C . n 
C 1 301 ASP 301 294 294 ASP ASP C . n 
C 1 302 ILE 302 295 295 ILE ILE C . n 
C 1 303 LEU 303 296 296 LEU LEU C . n 
C 1 304 CYS 304 297 297 CYS CYS C . n 
C 1 305 LEU 305 298 298 LEU LEU C . n 
C 1 306 ALA 306 299 299 ALA ALA C . n 
C 1 307 LYS 307 300 300 LYS LYS C . n 
C 1 308 ALA 308 301 301 ALA ALA C . n 
C 1 309 LEU 309 302 302 LEU LEU C . n 
C 1 310 GLY 310 303 303 GLY GLY C . n 
C 1 311 GLY 311 304 304 GLY GLY C . n 
C 1 312 GLY 312 305 305 GLY GLY C . n 
C 1 313 VAL 313 306 306 VAL VAL C . n 
C 1 314 MET 314 307 307 MET MET C . n 
C 1 315 PRO 315 308 308 PRO PRO C . n 
C 1 316 ILE 316 309 309 ILE ILE C . n 
C 1 317 GLY 317 310 310 GLY GLY C . n 
C 1 318 ALA 318 311 311 ALA ALA C . n 
C 1 319 THR 319 312 312 THR THR C . n 
C 1 320 ILE 320 313 313 ILE ILE C . n 
C 1 321 ALA 321 314 314 ALA ALA C . n 
C 1 322 THR 322 315 315 THR THR C . n 
C 1 323 GLU 323 316 316 GLU GLU C . n 
C 1 324 GLU 324 317 317 GLU GLU C . n 
C 1 325 VAL 325 318 318 VAL VAL C . n 
C 1 326 PHE 326 319 319 PHE PHE C . n 
C 1 327 SER 327 320 320 SER SER C . n 
C 1 328 VAL 328 321 321 VAL VAL C . n 
C 1 329 LEU 329 322 322 LEU LEU C . n 
C 1 330 PHE 330 323 323 PHE PHE C . n 
C 1 331 ASP 331 324 324 ASP ASP C . n 
C 1 332 ASN 332 325 325 ASN ASN C . n 
C 1 333 PRO 333 326 326 PRO PRO C . n 
C 1 334 PHE 334 327 327 PHE PHE C . n 
C 1 335 LEU 335 328 328 LEU LEU C . n 
C 1 336 HIS 336 329 329 HIS HIS C . n 
C 1 337 THR 337 330 330 THR THR C . n 
C 1 338 THR 338 331 331 THR THR C . n 
C 1 339 THR 339 332 332 THR THR C . n 
C 1 340 PHE 340 333 333 PHE PHE C . n 
C 1 341 GLY 341 334 334 GLY GLY C . n 
C 1 342 GLY 342 335 335 GLY GLY C . n 
C 1 343 ASN 343 336 336 ASN ASN C . n 
C 1 344 PRO 344 337 337 PRO PRO C . n 
C 1 345 LEU 345 338 338 LEU LEU C . n 
C 1 346 ALA 346 339 339 ALA ALA C . n 
C 1 347 CYS 347 340 340 CYS CYS C . n 
C 1 348 ALA 348 341 341 ALA ALA C . n 
C 1 349 ALA 349 342 342 ALA ALA C . n 
C 1 350 ALA 350 343 343 ALA ALA C . n 
C 1 351 LEU 351 344 344 LEU LEU C . n 
C 1 352 ALA 352 345 345 ALA ALA C . n 
C 1 353 THR 353 346 346 THR THR C . n 
C 1 354 ILE 354 347 347 ILE ILE C . n 
C 1 355 ASN 355 348 348 ASN ASN C . n 
C 1 356 VAL 356 349 349 VAL VAL C . n 
C 1 357 LEU 357 350 350 LEU LEU C . n 
C 1 358 LEU 358 351 351 LEU LEU C . n 
C 1 359 GLU 359 352 352 GLU GLU C . n 
C 1 360 GLN 360 353 353 GLN GLN C . n 
C 1 361 ASN 361 354 354 ASN ASN C . n 
C 1 362 LEU 362 355 355 LEU LEU C . n 
C 1 363 PRO 363 356 356 PRO PRO C . n 
C 1 364 ALA 364 357 357 ALA ALA C . n 
C 1 365 GLN 365 358 358 GLN GLN C . n 
C 1 366 ALA 366 359 359 ALA ALA C . n 
C 1 367 GLU 367 360 360 GLU GLU C . n 
C 1 368 GLN 368 361 361 GLN GLN C . n 
C 1 369 LYS 369 362 362 LYS LYS C . n 
C 1 370 GLY 370 363 363 GLY GLY C . n 
C 1 371 ASP 371 364 364 ASP ASP C . n 
C 1 372 MET 372 365 365 MET MET C . n 
C 1 373 LEU 373 366 366 LEU LEU C . n 
C 1 374 LEU 374 367 367 LEU LEU C . n 
C 1 375 ASP 375 368 368 ASP ASP C . n 
C 1 376 GLY 376 369 369 GLY GLY C . n 
C 1 377 PHE 377 370 370 PHE PHE C . n 
C 1 378 ARG 378 371 371 ARG ARG C . n 
C 1 379 GLN 379 372 372 GLN GLN C . n 
C 1 380 LEU 380 373 373 LEU LEU C . n 
C 1 381 ALA 381 374 374 ALA ALA C . n 
C 1 382 ARG 382 375 375 ARG ARG C . n 
C 1 383 GLU 383 376 376 GLU GLU C . n 
C 1 384 TYR 384 377 377 TYR TYR C . n 
C 1 385 PRO 385 378 378 PRO PRO C . n 
C 1 386 ASP 386 379 379 ASP ASP C . n 
C 1 387 LEU 387 380 380 LEU LEU C . n 
C 1 388 VAL 388 381 381 VAL VAL C . n 
C 1 389 GLN 389 382 382 GLN GLN C . n 
C 1 390 GLU 390 383 383 GLU GLU C . n 
C 1 391 ALA 391 384 384 ALA ALA C . n 
C 1 392 ARG 392 385 385 ARG ARG C . n 
C 1 393 GLY 393 386 386 GLY GLY C . n 
C 1 394 LYS 394 387 387 LYS LYS C . n 
C 1 395 GLY 395 388 388 GLY GLY C . n 
C 1 396 MET 396 389 389 MET MET C . n 
C 1 397 LEU 397 390 390 LEU LEU C . n 
C 1 398 MET 398 391 391 MET MET C . n 
C 1 399 ALA 399 392 392 ALA ALA C . n 
C 1 400 ILE 400 393 393 ILE ILE C . n 
C 1 401 GLU 401 394 394 GLU GLU C . n 
C 1 402 PHE 402 395 395 PHE PHE C . n 
C 1 403 VAL 403 396 396 VAL VAL C . n 
C 1 404 ASP 404 397 397 ASP ASP C . n 
C 1 405 ASN 405 398 398 ASN ASN C . n 
C 1 406 GLU 406 399 399 GLU GLU C . n 
C 1 407 ILE 407 400 400 ILE ILE C . n 
C 1 408 GLY 408 401 401 GLY GLY C . n 
C 1 409 TYR 409 402 402 TYR TYR C . n 
C 1 410 ASN 410 403 403 ASN ASN C . n 
C 1 411 PHE 411 404 404 PHE PHE C . n 
C 1 412 ALA 412 405 405 ALA ALA C . n 
C 1 413 SER 413 406 406 SER SER C . n 
C 1 414 GLU 414 407 407 GLU GLU C . n 
C 1 415 MET 415 408 408 MET MET C . n 
C 1 416 PHE 416 409 409 PHE PHE C . n 
C 1 417 ARG 417 410 410 ARG ARG C . n 
C 1 418 GLN 418 411 411 GLN GLN C . n 
C 1 419 ARG 419 412 412 ARG ARG C . n 
C 1 420 VAL 420 413 413 VAL VAL C . n 
C 1 421 LEU 421 414 414 LEU LEU C . n 
C 1 422 VAL 422 415 415 VAL VAL C . n 
C 1 423 ALA 423 416 416 ALA ALA C . n 
C 1 424 GLY 424 417 417 GLY GLY C . n 
C 1 425 THR 425 418 418 THR THR C . n 
C 1 426 LEU 426 419 419 LEU LEU C . n 
C 1 427 ASN 427 420 420 ASN ASN C . n 
C 1 428 ASN 428 421 421 ASN ASN C . n 
C 1 429 ALA 429 422 422 ALA ALA C . n 
C 1 430 LYS 430 423 423 LYS LYS C . n 
C 1 431 THR 431 424 424 THR THR C . n 
C 1 432 ILE 432 425 425 ILE ILE C . n 
C 1 433 ARG 433 426 426 ARG ARG C . n 
C 1 434 ILE 434 427 427 ILE ILE C . n 
C 1 435 GLU 435 428 428 GLU GLU C . n 
C 1 436 PRO 436 429 429 PRO PRO C . n 
C 1 437 PRO 437 430 430 PRO PRO C . n 
C 1 438 LEU 438 431 431 LEU LEU C . n 
C 1 439 THR 439 432 432 THR THR C . n 
C 1 440 LEU 440 433 433 LEU LEU C . n 
C 1 441 THR 441 434 434 THR THR C . n 
C 1 442 ILE 442 435 435 ILE ILE C . n 
C 1 443 GLU 443 436 436 GLU GLU C . n 
C 1 444 GLN 444 437 437 GLN GLN C . n 
C 1 445 CYS 445 438 438 CYS CYS C . n 
C 1 446 GLU 446 439 439 GLU GLU C . n 
C 1 447 LEU 447 440 440 LEU LEU C . n 
C 1 448 VAL 448 441 441 VAL VAL C . n 
C 1 449 ILE 449 442 442 ILE ILE C . n 
C 1 450 LYS 450 443 443 LYS LYS C . n 
C 1 451 ALA 451 444 444 ALA ALA C . n 
C 1 452 ALA 452 445 445 ALA ALA C . n 
C 1 453 ARG 453 446 446 ARG ARG C . n 
C 1 454 LYS 454 447 447 LYS LYS C . n 
C 1 455 ALA 455 448 448 ALA ALA C . n 
C 1 456 LEU 456 449 449 LEU LEU C . n 
C 1 457 ALA 457 450 450 ALA ALA C . n 
C 1 458 ALA 458 451 451 ALA ALA C . n 
C 1 459 MET 459 452 452 MET MET C . n 
C 1 460 ARG 460 453 453 ARG ARG C . n 
C 1 461 VAL 461 454 454 VAL VAL C . n 
C 1 462 SER 462 455 455 SER SER C . n 
C 1 463 VAL 463 456 456 VAL VAL C . n 
C 1 464 GLU 464 457 457 GLU GLU C . n 
C 1 465 GLU 465 458 458 GLU GLU C . n 
C 1 466 ALA 466 459 459 ALA ALA C . n 
C 1 467 LEU 467 460 460 LEU LEU C . n 
C 1 468 GLU 468 461 461 GLU GLU C . n 
C 1 469 VAL 469 462 462 VAL VAL C . n 
C 1 470 SER 470 463 463 SER SER C . n 
C 1 471 ALA 471 464 464 ALA ALA C . n 
C 1 472 LYS 472 465 465 LYS LYS C . n 
C 1 473 GLU 473 466 466 GLU GLU C . n 
C 1 474 GLN 474 467 467 GLN GLN C . n 
C 1 475 GLN 475 468 468 GLN GLN C . n 
C 1 476 ASN 476 469 ?   ?   ?   C . n 
C 1 477 ALA 477 470 ?   ?   ?   C . n 
C 1 478 PHE 478 471 ?   ?   ?   C . n 
C 1 479 TYR 479 472 ?   ?   ?   C . n 
C 1 480 GLU 480 473 ?   ?   ?   C . n 
C 1 481 ILE 481 474 ?   ?   ?   C . n 
C 1 482 LEU 482 475 ?   ?   ?   C . n 
C 1 483 HIS 483 476 ?   ?   ?   C . n 
C 1 484 LEU 484 477 ?   ?   ?   C . n 
C 1 485 PRO 485 478 ?   ?   ?   C . n 
C 1 486 ASN 486 479 ?   ?   ?   C . n 
C 1 487 LEU 487 480 ?   ?   ?   C . n 
C 1 488 ASN 488 481 ?   ?   ?   C . n 
C 1 489 GLU 489 482 ?   ?   ?   C . n 
C 1 490 GLU 490 483 ?   ?   ?   C . n 
C 1 491 GLN 491 484 ?   ?   ?   C . n 
C 1 492 ARG 492 485 ?   ?   ?   C . n 
C 1 493 ASN 493 486 ?   ?   ?   C . n 
C 1 494 ALA 494 487 ?   ?   ?   C . n 
C 1 495 PHE 495 488 ?   ?   ?   C . n 
C 1 496 ILE 496 489 ?   ?   ?   C . n 
C 1 497 GLN 497 490 ?   ?   ?   C . n 
C 1 498 SER 498 491 ?   ?   ?   C . n 
C 1 499 LEU 499 492 ?   ?   ?   C . n 
C 1 500 LYS 500 493 ?   ?   ?   C . n 
C 1 501 ASP 501 494 ?   ?   ?   C . n 
C 1 502 ASP 502 495 ?   ?   ?   C . n 
C 1 503 PRO 503 496 ?   ?   ?   C . n 
C 1 504 SER 504 497 ?   ?   ?   C . n 
C 1 505 GLN 505 498 ?   ?   ?   C . n 
C 1 506 SER 506 499 ?   ?   ?   C . n 
C 1 507 ALA 507 500 ?   ?   ?   C . n 
C 1 508 ASN 508 501 ?   ?   ?   C . n 
C 1 509 LEU 509 502 ?   ?   ?   C . n 
C 1 510 LEU 510 503 ?   ?   ?   C . n 
C 1 511 ALA 511 504 ?   ?   ?   C . n 
C 1 512 GLU 512 505 ?   ?   ?   C . n 
C 1 513 ALA 513 506 ?   ?   ?   C . n 
C 1 514 LYS 514 507 ?   ?   ?   C . n 
C 1 515 LYS 515 508 ?   ?   ?   C . n 
C 1 516 LEU 516 509 ?   ?   ?   C . n 
C 1 517 ASN 517 510 ?   ?   ?   C . n 
C 1 518 ASP 518 511 ?   ?   ?   C . n 
C 1 519 ALA 519 512 ?   ?   ?   C . n 
C 1 520 GLN 520 513 ?   ?   ?   C . n 
C 1 521 ALA 521 514 ?   ?   ?   C . n 
C 1 522 PRO 522 515 ?   ?   ?   C . n 
C 1 523 LYS 523 516 ?   ?   ?   C . n 
D 1 1   GLY 1   -6  ?   ?   ?   D . n 
D 1 2   SER 2   -5  ?   ?   ?   D . n 
D 1 3   SER 3   -4  ?   ?   ?   D . n 
D 1 4   HIS 4   -3  ?   ?   ?   D . n 
D 1 5   HIS 5   -2  ?   ?   ?   D . n 
D 1 6   HIS 6   -1  ?   ?   ?   D . n 
D 1 7   HIS 7   0   ?   ?   ?   D . n 
D 1 8   HIS 8   1   ?   ?   ?   D . n 
D 1 9   HIS 9   2   ?   ?   ?   D . n 
D 1 10  TYR 10  3   ?   ?   ?   D . n 
D 1 11  TYR 11  4   ?   ?   ?   D . n 
D 1 12  LEU 12  5   ?   ?   ?   D . n 
D 1 13  GLU 13  6   ?   ?   ?   D . n 
D 1 14  SER 14  7   ?   ?   ?   D . n 
D 1 15  ALA 15  8   8   ALA ALA D . n 
D 1 16  SER 16  9   9   SER SER D . n 
D 1 17  ALA 17  10  10  ALA ALA D . n 
D 1 18  LEU 18  11  11  LEU LEU D . n 
D 1 19  ALA 19  12  12  ALA ALA D . n 
D 1 20  CYS 20  13  13  CYS CYS D . n 
D 1 21  SER 21  14  14  SER SER D . n 
D 1 22  ALA 22  15  15  ALA ALA D . n 
D 1 23  HIS 23  16  16  HIS HIS D . n 
D 1 24  ALA 24  17  17  ALA ALA D . n 
D 1 25  LEU 25  18  18  LEU LEU D . n 
D 1 26  ASN 26  19  19  ASN ASN D . n 
D 1 27  LEU 27  20  20  LEU LEU D . n 
D 1 28  ILE 28  21  21  ILE ILE D . n 
D 1 29  GLU 29  22  22  GLU GLU D . n 
D 1 30  LYS 30  23  23  LYS LYS D . n 
D 1 31  ARG 31  24  24  ARG ARG D . n 
D 1 32  THR 32  25  25  THR THR D . n 
D 1 33  LEU 33  26  26  LEU LEU D . n 
D 1 34  ASP 34  27  27  ASP ASP D . n 
D 1 35  HIS 35  28  28  HIS HIS D . n 
D 1 36  GLU 36  29  29  GLU GLU D . n 
D 1 37  GLU 37  30  30  GLU GLU D . n 
D 1 38  MET 38  31  31  MET MET D . n 
D 1 39  LYS 39  32  32  LYS LYS D . n 
D 1 40  ALA 40  33  33  ALA ALA D . n 
D 1 41  LEU 41  34  34  LEU LEU D . n 
D 1 42  ASN 42  35  35  ASN ASN D . n 
D 1 43  ARG 43  36  36  ARG ARG D . n 
D 1 44  GLU 44  37  37  GLU GLU D . n 
D 1 45  VAL 45  38  38  VAL VAL D . n 
D 1 46  ILE 46  39  39  ILE ILE D . n 
D 1 47  GLU 47  40  40  GLU GLU D . n 
D 1 48  TYR 48  41  41  TYR TYR D . n 
D 1 49  PHE 49  42  42  PHE PHE D . n 
D 1 50  LYS 50  43  43  LYS LYS D . n 
D 1 51  GLU 51  44  44  GLU GLU D . n 
D 1 52  HIS 52  45  45  HIS HIS D . n 
D 1 53  VAL 53  46  46  VAL VAL D . n 
D 1 54  ASN 54  47  47  ASN ASN D . n 
D 1 55  PRO 55  48  48  PRO PRO D . n 
D 1 56  GLY 56  49  49  GLY GLY D . n 
D 1 57  PHE 57  50  50  PHE PHE D . n 
D 1 58  LEU 58  51  51  LEU LEU D . n 
D 1 59  GLU 59  52  52  GLU GLU D . n 
D 1 60  TYR 60  53  53  TYR TYR D . n 
D 1 61  ARG 61  54  54  ARG ARG D . n 
D 1 62  LYS 62  55  55  LYS LYS D . n 
D 1 63  SER 63  56  56  SER SER D . n 
D 1 64  VAL 64  57  57  VAL VAL D . n 
D 1 65  THR 65  58  58  THR THR D . n 
D 1 66  ALA 66  59  59  ALA ALA D . n 
D 1 67  GLY 67  60  60  GLY GLY D . n 
D 1 68  GLY 68  61  61  GLY GLY D . n 
D 1 69  ASP 69  62  62  ASP ASP D . n 
D 1 70  TYR 70  63  63  TYR TYR D . n 
D 1 71  GLY 71  64  64  GLY GLY D . n 
D 1 72  ALA 72  65  65  ALA ALA D . n 
D 1 73  VAL 73  66  66  VAL VAL D . n 
D 1 74  GLU 74  67  67  GLU GLU D . n 
D 1 75  TRP 75  68  68  TRP TRP D . n 
D 1 76  GLN 76  69  69  GLN GLN D . n 
D 1 77  ALA 77  70  70  ALA ALA D . n 
D 1 78  GLY 78  71  71  GLY GLY D . n 
D 1 79  SER 79  72  72  SER SER D . n 
D 1 80  LEU 80  73  73  LEU LEU D . n 
D 1 81  ASN 81  74  74  ASN ASN D . n 
D 1 82  THR 82  75  75  THR THR D . n 
D 1 83  LEU 83  76  76  LEU LEU D . n 
D 1 84  VAL 84  77  77  VAL VAL D . n 
D 1 85  ASP 85  78  78  ASP ASP D . n 
D 1 86  THR 86  79  79  THR THR D . n 
D 1 87  GLN 87  80  80  GLN GLN D . n 
D 1 88  GLY 88  81  81  GLY GLY D . n 
D 1 89  GLN 89  82  82  GLN GLN D . n 
D 1 90  GLU 90  83  83  GLU GLU D . n 
D 1 91  PHE 91  84  84  PHE PHE D . n 
D 1 92  ILE 92  85  85  ILE ILE D . n 
D 1 93  ASP 93  86  86  ASP ASP D . n 
D 1 94  CYS 94  87  87  CYS CYS D . n 
D 1 95  LEU 95  88  88  LEU LEU D . n 
D 1 96  GLY 96  89  89  GLY GLY D . n 
D 1 97  GLY 97  90  90  GLY GLY D . n 
D 1 98  PHE 98  91  91  PHE PHE D . n 
D 1 99  GLY 99  92  92  GLY GLY D . n 
D 1 100 ILE 100 93  93  ILE ILE D . n 
D 1 101 PHE 101 94  94  PHE PHE D . n 
D 1 102 ASN 102 95  95  ASN ASN D . n 
D 1 103 VAL 103 96  96  VAL VAL D . n 
D 1 104 GLY 104 97  97  GLY GLY D . n 
D 1 105 HIS 105 98  98  HIS HIS D . n 
D 1 106 ARG 106 99  99  ARG ARG D . n 
D 1 107 ASN 107 100 100 ASN ASN D . n 
D 1 108 PRO 108 101 101 PRO PRO D . n 
D 1 109 VAL 109 102 102 VAL VAL D . n 
D 1 110 VAL 110 103 103 VAL VAL D . n 
D 1 111 VAL 111 104 104 VAL VAL D . n 
D 1 112 SER 112 105 105 SER SER D . n 
D 1 113 ALA 113 106 106 ALA ALA D . n 
D 1 114 VAL 114 107 107 VAL VAL D . n 
D 1 115 GLN 115 108 108 GLN GLN D . n 
D 1 116 ASN 116 109 109 ASN ASN D . n 
D 1 117 GLN 117 110 110 GLN GLN D . n 
D 1 118 LEU 118 111 111 LEU LEU D . n 
D 1 119 ALA 119 112 112 ALA ALA D . n 
D 1 120 LYS 120 113 113 LYS LYS D . n 
D 1 121 GLN 121 114 114 GLN GLN D . n 
D 1 122 PRO 122 115 115 PRO PRO D . n 
D 1 123 LEU 123 116 116 LEU LEU D . n 
D 1 124 HIS 124 117 117 HIS HIS D . n 
D 1 125 SER 125 118 118 SER SER D . n 
D 1 126 GLN 126 119 119 GLN GLN D . n 
D 1 127 GLU 127 120 120 GLU GLU D . n 
D 1 128 LEU 128 121 121 LEU LEU D . n 
D 1 129 LEU 129 122 122 LEU LEU D . n 
D 1 130 ASP 130 123 123 ASP ASP D . n 
D 1 131 PRO 131 124 124 PRO PRO D . n 
D 1 132 LEU 132 125 125 LEU LEU D . n 
D 1 133 ARG 133 126 126 ARG ARG D . n 
D 1 134 ALA 134 127 127 ALA ALA D . n 
D 1 135 MET 135 128 128 MET MET D . n 
D 1 136 LEU 136 129 129 LEU LEU D . n 
D 1 137 ALA 137 130 130 ALA ALA D . n 
D 1 138 LYS 138 131 131 LYS LYS D . n 
D 1 139 THR 139 132 132 THR THR D . n 
D 1 140 LEU 140 133 133 LEU LEU D . n 
D 1 141 ALA 141 134 134 ALA ALA D . n 
D 1 142 ALA 142 135 135 ALA ALA D . n 
D 1 143 LEU 143 136 136 LEU LEU D . n 
D 1 144 THR 144 137 137 THR THR D . n 
D 1 145 PRO 145 138 138 PRO PRO D . n 
D 1 146 GLY 146 139 139 GLY GLY D . n 
D 1 147 LYS 147 140 140 LYS LYS D . n 
D 1 148 LEU 148 141 141 LEU LEU D . n 
D 1 149 LYS 149 142 142 LYS LYS D . n 
D 1 150 TYR 150 143 143 TYR TYR D . n 
D 1 151 SER 151 144 144 SER SER D . n 
D 1 152 PHE 152 145 145 PHE PHE D . n 
D 1 153 PHE 153 146 146 PHE PHE D . n 
D 1 154 CYS 154 147 147 CYS CYS D . n 
D 1 155 ASN 155 148 148 ASN ASN D . n 
D 1 156 SER 156 149 149 SER SER D . n 
D 1 157 GLY 157 150 150 GLY GLY D . n 
D 1 158 THR 158 151 151 THR THR D . n 
D 1 159 GLU 159 152 152 GLU GLU D . n 
D 1 160 SER 160 153 153 SER SER D . n 
D 1 161 VAL 161 154 154 VAL VAL D . n 
D 1 162 GLU 162 155 155 GLU GLU D . n 
D 1 163 ALA 163 156 156 ALA ALA D . n 
D 1 164 ALA 164 157 157 ALA ALA D . n 
D 1 165 LEU 165 158 158 LEU LEU D . n 
D 1 166 LYS 166 159 159 LYS LYS D . n 
D 1 167 LEU 167 160 160 LEU LEU D . n 
D 1 168 ALA 168 161 161 ALA ALA D . n 
D 1 169 LYS 169 162 162 LYS LYS D . n 
D 1 170 ALA 170 163 163 ALA ALA D . n 
D 1 171 TYR 171 164 164 TYR TYR D . n 
D 1 172 GLN 172 165 165 GLN GLN D . n 
D 1 173 SER 173 166 166 SER SER D . n 
D 1 174 PRO 174 167 167 PRO PRO D . n 
D 1 175 ARG 175 168 168 ARG ARG D . n 
D 1 176 GLY 176 169 169 GLY GLY D . n 
D 1 177 LYS 177 170 170 LYS LYS D . n 
D 1 178 PHE 178 171 171 PHE PHE D . n 
D 1 179 THR 179 172 172 THR THR D . n 
D 1 180 PHE 180 173 173 PHE PHE D . n 
D 1 181 ILE 181 174 174 ILE ILE D . n 
D 1 182 ALA 182 175 175 ALA ALA D . n 
D 1 183 THR 183 176 176 THR THR D . n 
D 1 184 SER 184 177 177 SER SER D . n 
D 1 185 GLY 185 178 178 GLY GLY D . n 
D 1 186 ALA 186 179 179 ALA ALA D . n 
D 1 187 PHE 187 180 180 PHE PHE D . n 
D 1 188 HIS 188 181 181 HIS HIS D . n 
D 1 189 GLY 189 182 182 GLY GLY D . n 
D 1 190 LYS 190 183 183 LYS LYS D . n 
D 1 191 SER 191 184 184 SER SER D . n 
D 1 192 LEU 192 185 185 LEU LEU D . n 
D 1 193 GLY 193 186 186 GLY GLY D . n 
D 1 194 ALA 194 187 187 ALA ALA D . n 
D 1 195 LEU 195 188 188 LEU LEU D . n 
D 1 196 SER 196 189 189 SER SER D . n 
D 1 197 ALA 197 190 190 ALA ALA D . n 
D 1 198 THR 198 191 191 THR THR D . n 
D 1 199 ALA 199 192 192 ALA ALA D . n 
D 1 200 LYS 200 193 193 LYS LYS D . n 
D 1 201 SER 201 194 194 SER SER D . n 
D 1 202 THR 202 195 195 THR THR D . n 
D 1 203 PHE 203 196 196 PHE PHE D . n 
D 1 204 ARG 204 197 197 ARG ARG D . n 
D 1 205 LYS 205 198 198 LYS LYS D . n 
D 1 206 PRO 206 199 199 PRO PRO D . n 
D 1 207 PHE 207 200 200 PHE PHE D . n 
D 1 208 MET 208 201 201 MET MET D . n 
D 1 209 PRO 209 202 202 PRO PRO D . n 
D 1 210 LEU 210 203 203 LEU LEU D . n 
D 1 211 LEU 211 204 204 LEU LEU D . n 
D 1 212 PRO 212 205 205 PRO PRO D . n 
D 1 213 GLY 213 206 206 GLY GLY D . n 
D 1 214 PHE 214 207 207 PHE PHE D . n 
D 1 215 ARG 215 208 208 ARG ARG D . n 
D 1 216 HIS 216 209 209 HIS HIS D . n 
D 1 217 VAL 217 210 210 VAL VAL D . n 
D 1 218 PRO 218 211 211 PRO PRO D . n 
D 1 219 PHE 219 212 212 PHE PHE D . n 
D 1 220 GLY 220 213 213 GLY GLY D . n 
D 1 221 ASN 221 214 214 ASN ASN D . n 
D 1 222 ILE 222 215 215 ILE ILE D . n 
D 1 223 GLU 223 216 216 GLU GLU D . n 
D 1 224 ALA 224 217 217 ALA ALA D . n 
D 1 225 MET 225 218 218 MET MET D . n 
D 1 226 ARG 226 219 219 ARG ARG D . n 
D 1 227 THR 227 220 220 THR THR D . n 
D 1 228 ALA 228 221 221 ALA ALA D . n 
D 1 229 LEU 229 222 222 LEU LEU D . n 
D 1 230 ASN 230 223 223 ASN ASN D . n 
D 1 231 GLU 231 224 224 GLU GLU D . n 
D 1 232 CYS 232 225 225 CYS CYS D . n 
D 1 233 LYS 233 226 226 LYS LYS D . n 
D 1 234 LYS 234 227 227 LYS LYS D . n 
D 1 235 THR 235 228 228 THR THR D . n 
D 1 236 GLY 236 229 229 GLY GLY D . n 
D 1 237 ASP 237 230 230 ASP ASP D . n 
D 1 238 ASP 238 231 231 ASP ASP D . n 
D 1 239 VAL 239 232 232 VAL VAL D . n 
D 1 240 ALA 240 233 233 ALA ALA D . n 
D 1 241 ALA 241 234 234 ALA ALA D . n 
D 1 242 VAL 242 235 235 VAL VAL D . n 
D 1 243 ILE 243 236 236 ILE ILE D . n 
D 1 244 LEU 244 237 237 LEU LEU D . n 
D 1 245 GLU 245 238 238 GLU GLU D . n 
D 1 246 PRO 246 239 239 PRO PRO D . n 
D 1 247 ILE 247 240 240 ILE ILE D . n 
D 1 248 GLN 248 241 241 GLN GLN D . n 
D 1 249 GLY 249 242 242 GLY GLY D . n 
D 1 250 GLU 250 243 243 GLU GLU D . n 
D 1 251 GLY 251 244 244 GLY GLY D . n 
D 1 252 GLY 252 245 245 GLY GLY D . n 
D 1 253 VAL 253 246 246 VAL VAL D . n 
D 1 254 ILE 254 247 247 ILE ILE D . n 
D 1 255 LEU 255 248 248 LEU LEU D . n 
D 1 256 PRO 256 249 249 PRO PRO D . n 
D 1 257 PRO 257 250 250 PRO PRO D . n 
D 1 258 PRO 258 251 251 PRO PRO D . n 
D 1 259 GLY 259 252 252 GLY GLY D . n 
D 1 260 TYR 260 253 253 TYR TYR D . n 
D 1 261 LEU 261 254 254 LEU LEU D . n 
D 1 262 THR 262 255 255 THR THR D . n 
D 1 263 ALA 263 256 256 ALA ALA D . n 
D 1 264 VAL 264 257 257 VAL VAL D . n 
D 1 265 ARG 265 258 258 ARG ARG D . n 
D 1 266 LYS 266 259 259 LYS LYS D . n 
D 1 267 LEU 267 260 260 LEU LEU D . n 
D 1 268 CYS 268 261 261 CYS CYS D . n 
D 1 269 ASP 269 262 262 ASP ASP D . n 
D 1 270 GLU 270 263 263 GLU GLU D . n 
D 1 271 PHE 271 264 264 PHE PHE D . n 
D 1 272 GLY 272 265 265 GLY GLY D . n 
D 1 273 ALA 273 266 266 ALA ALA D . n 
D 1 274 LEU 274 267 267 LEU LEU D . n 
D 1 275 MET 275 268 268 MET MET D . n 
D 1 276 ILE 276 269 269 ILE ILE D . n 
D 1 277 LEU 277 270 270 LEU LEU D . n 
D 1 278 ASP 278 271 271 ASP ASP D . n 
D 1 279 GLU 279 272 272 GLU GLU D . n 
D 1 280 VAL 280 273 273 VAL VAL D . n 
D 1 281 GLN 281 274 274 GLN GLN D . n 
D 1 282 THR 282 275 275 THR THR D . n 
D 1 283 GLY 283 276 276 GLY GLY D . n 
D 1 284 MET 284 277 277 MET MET D . n 
D 1 285 GLY 285 278 278 GLY GLY D . n 
D 1 286 ARG 286 279 279 ARG ARG D . n 
D 1 287 THR 287 280 280 THR THR D . n 
D 1 288 GLY 288 281 281 GLY GLY D . n 
D 1 289 LYS 289 282 282 LYS LYS D . n 
D 1 290 MET 290 283 283 MET MET D . n 
D 1 291 PHE 291 284 284 PHE PHE D . n 
D 1 292 ALA 292 285 285 ALA ALA D . n 
D 1 293 CYS 293 286 286 CYS CYS D . n 
D 1 294 GLU 294 287 287 GLU GLU D . n 
D 1 295 HIS 295 288 288 HIS HIS D . n 
D 1 296 GLU 296 289 289 GLU GLU D . n 
D 1 297 ASN 297 290 290 ASN ASN D . n 
D 1 298 VAL 298 291 291 VAL VAL D . n 
D 1 299 GLN 299 292 292 GLN GLN D . n 
D 1 300 PRO 300 293 293 PRO PRO D . n 
D 1 301 ASP 301 294 294 ASP ASP D . n 
D 1 302 ILE 302 295 295 ILE ILE D . n 
D 1 303 LEU 303 296 296 LEU LEU D . n 
D 1 304 CYS 304 297 297 CYS CYS D . n 
D 1 305 LEU 305 298 298 LEU LEU D . n 
D 1 306 ALA 306 299 299 ALA ALA D . n 
D 1 307 LYS 307 300 300 LYS LYS D . n 
D 1 308 ALA 308 301 301 ALA ALA D . n 
D 1 309 LEU 309 302 302 LEU LEU D . n 
D 1 310 GLY 310 303 303 GLY GLY D . n 
D 1 311 GLY 311 304 304 GLY GLY D . n 
D 1 312 GLY 312 305 305 GLY GLY D . n 
D 1 313 VAL 313 306 306 VAL VAL D . n 
D 1 314 MET 314 307 307 MET MET D . n 
D 1 315 PRO 315 308 308 PRO PRO D . n 
D 1 316 ILE 316 309 309 ILE ILE D . n 
D 1 317 GLY 317 310 310 GLY GLY D . n 
D 1 318 ALA 318 311 311 ALA ALA D . n 
D 1 319 THR 319 312 312 THR THR D . n 
D 1 320 ILE 320 313 313 ILE ILE D . n 
D 1 321 ALA 321 314 314 ALA ALA D . n 
D 1 322 THR 322 315 315 THR THR D . n 
D 1 323 GLU 323 316 316 GLU GLU D . n 
D 1 324 GLU 324 317 317 GLU GLU D . n 
D 1 325 VAL 325 318 318 VAL VAL D . n 
D 1 326 PHE 326 319 319 PHE PHE D . n 
D 1 327 SER 327 320 320 SER SER D . n 
D 1 328 VAL 328 321 321 VAL VAL D . n 
D 1 329 LEU 329 322 322 LEU LEU D . n 
D 1 330 PHE 330 323 323 PHE PHE D . n 
D 1 331 ASP 331 324 324 ASP ASP D . n 
D 1 332 ASN 332 325 325 ASN ASN D . n 
D 1 333 PRO 333 326 326 PRO PRO D . n 
D 1 334 PHE 334 327 327 PHE PHE D . n 
D 1 335 LEU 335 328 328 LEU LEU D . n 
D 1 336 HIS 336 329 329 HIS HIS D . n 
D 1 337 THR 337 330 330 THR THR D . n 
D 1 338 THR 338 331 331 THR THR D . n 
D 1 339 THR 339 332 332 THR THR D . n 
D 1 340 PHE 340 333 333 PHE PHE D . n 
D 1 341 GLY 341 334 334 GLY GLY D . n 
D 1 342 GLY 342 335 335 GLY GLY D . n 
D 1 343 ASN 343 336 336 ASN ASN D . n 
D 1 344 PRO 344 337 337 PRO PRO D . n 
D 1 345 LEU 345 338 338 LEU LEU D . n 
D 1 346 ALA 346 339 339 ALA ALA D . n 
D 1 347 CYS 347 340 340 CYS CYS D . n 
D 1 348 ALA 348 341 341 ALA ALA D . n 
D 1 349 ALA 349 342 342 ALA ALA D . n 
D 1 350 ALA 350 343 343 ALA ALA D . n 
D 1 351 LEU 351 344 344 LEU LEU D . n 
D 1 352 ALA 352 345 345 ALA ALA D . n 
D 1 353 THR 353 346 346 THR THR D . n 
D 1 354 ILE 354 347 347 ILE ILE D . n 
D 1 355 ASN 355 348 348 ASN ASN D . n 
D 1 356 VAL 356 349 349 VAL VAL D . n 
D 1 357 LEU 357 350 350 LEU LEU D . n 
D 1 358 LEU 358 351 351 LEU LEU D . n 
D 1 359 GLU 359 352 352 GLU GLU D . n 
D 1 360 GLN 360 353 353 GLN GLN D . n 
D 1 361 ASN 361 354 354 ASN ASN D . n 
D 1 362 LEU 362 355 355 LEU LEU D . n 
D 1 363 PRO 363 356 356 PRO PRO D . n 
D 1 364 ALA 364 357 357 ALA ALA D . n 
D 1 365 GLN 365 358 358 GLN GLN D . n 
D 1 366 ALA 366 359 359 ALA ALA D . n 
D 1 367 GLU 367 360 360 GLU GLU D . n 
D 1 368 GLN 368 361 361 GLN GLN D . n 
D 1 369 LYS 369 362 362 LYS LYS D . n 
D 1 370 GLY 370 363 363 GLY GLY D . n 
D 1 371 ASP 371 364 364 ASP ASP D . n 
D 1 372 MET 372 365 365 MET MET D . n 
D 1 373 LEU 373 366 366 LEU LEU D . n 
D 1 374 LEU 374 367 367 LEU LEU D . n 
D 1 375 ASP 375 368 368 ASP ASP D . n 
D 1 376 GLY 376 369 369 GLY GLY D . n 
D 1 377 PHE 377 370 370 PHE PHE D . n 
D 1 378 ARG 378 371 371 ARG ARG D . n 
D 1 379 GLN 379 372 372 GLN GLN D . n 
D 1 380 LEU 380 373 373 LEU LEU D . n 
D 1 381 ALA 381 374 374 ALA ALA D . n 
D 1 382 ARG 382 375 375 ARG ARG D . n 
D 1 383 GLU 383 376 376 GLU GLU D . n 
D 1 384 TYR 384 377 377 TYR TYR D . n 
D 1 385 PRO 385 378 378 PRO PRO D . n 
D 1 386 ASP 386 379 379 ASP ASP D . n 
D 1 387 LEU 387 380 380 LEU LEU D . n 
D 1 388 VAL 388 381 381 VAL VAL D . n 
D 1 389 GLN 389 382 382 GLN GLN D . n 
D 1 390 GLU 390 383 383 GLU GLU D . n 
D 1 391 ALA 391 384 384 ALA ALA D . n 
D 1 392 ARG 392 385 385 ARG ARG D . n 
D 1 393 GLY 393 386 386 GLY GLY D . n 
D 1 394 LYS 394 387 387 LYS LYS D . n 
D 1 395 GLY 395 388 388 GLY GLY D . n 
D 1 396 MET 396 389 389 MET MET D . n 
D 1 397 LEU 397 390 390 LEU LEU D . n 
D 1 398 MET 398 391 391 MET MET D . n 
D 1 399 ALA 399 392 392 ALA ALA D . n 
D 1 400 ILE 400 393 393 ILE ILE D . n 
D 1 401 GLU 401 394 394 GLU GLU D . n 
D 1 402 PHE 402 395 395 PHE PHE D . n 
D 1 403 VAL 403 396 396 VAL VAL D . n 
D 1 404 ASP 404 397 397 ASP ASP D . n 
D 1 405 ASN 405 398 398 ASN ASN D . n 
D 1 406 GLU 406 399 399 GLU GLU D . n 
D 1 407 ILE 407 400 400 ILE ILE D . n 
D 1 408 GLY 408 401 401 GLY GLY D . n 
D 1 409 TYR 409 402 402 TYR TYR D . n 
D 1 410 ASN 410 403 403 ASN ASN D . n 
D 1 411 PHE 411 404 404 PHE PHE D . n 
D 1 412 ALA 412 405 405 ALA ALA D . n 
D 1 413 SER 413 406 406 SER SER D . n 
D 1 414 GLU 414 407 407 GLU GLU D . n 
D 1 415 MET 415 408 408 MET MET D . n 
D 1 416 PHE 416 409 409 PHE PHE D . n 
D 1 417 ARG 417 410 410 ARG ARG D . n 
D 1 418 GLN 418 411 411 GLN GLN D . n 
D 1 419 ARG 419 412 412 ARG ARG D . n 
D 1 420 VAL 420 413 413 VAL VAL D . n 
D 1 421 LEU 421 414 414 LEU LEU D . n 
D 1 422 VAL 422 415 415 VAL VAL D . n 
D 1 423 ALA 423 416 416 ALA ALA D . n 
D 1 424 GLY 424 417 417 GLY GLY D . n 
D 1 425 THR 425 418 418 THR THR D . n 
D 1 426 LEU 426 419 419 LEU LEU D . n 
D 1 427 ASN 427 420 420 ASN ASN D . n 
D 1 428 ASN 428 421 421 ASN ASN D . n 
D 1 429 ALA 429 422 422 ALA ALA D . n 
D 1 430 LYS 430 423 423 LYS LYS D . n 
D 1 431 THR 431 424 424 THR THR D . n 
D 1 432 ILE 432 425 425 ILE ILE D . n 
D 1 433 ARG 433 426 426 ARG ARG D . n 
D 1 434 ILE 434 427 427 ILE ILE D . n 
D 1 435 GLU 435 428 428 GLU GLU D . n 
D 1 436 PRO 436 429 429 PRO PRO D . n 
D 1 437 PRO 437 430 430 PRO PRO D . n 
D 1 438 LEU 438 431 431 LEU LEU D . n 
D 1 439 THR 439 432 432 THR THR D . n 
D 1 440 LEU 440 433 433 LEU LEU D . n 
D 1 441 THR 441 434 434 THR THR D . n 
D 1 442 ILE 442 435 435 ILE ILE D . n 
D 1 443 GLU 443 436 436 GLU GLU D . n 
D 1 444 GLN 444 437 437 GLN GLN D . n 
D 1 445 CYS 445 438 438 CYS CYS D . n 
D 1 446 GLU 446 439 439 GLU GLU D . n 
D 1 447 LEU 447 440 440 LEU LEU D . n 
D 1 448 VAL 448 441 441 VAL VAL D . n 
D 1 449 ILE 449 442 442 ILE ILE D . n 
D 1 450 LYS 450 443 443 LYS LYS D . n 
D 1 451 ALA 451 444 444 ALA ALA D . n 
D 1 452 ALA 452 445 445 ALA ALA D . n 
D 1 453 ARG 453 446 446 ARG ARG D . n 
D 1 454 LYS 454 447 447 LYS LYS D . n 
D 1 455 ALA 455 448 448 ALA ALA D . n 
D 1 456 LEU 456 449 449 LEU LEU D . n 
D 1 457 ALA 457 450 450 ALA ALA D . n 
D 1 458 ALA 458 451 451 ALA ALA D . n 
D 1 459 MET 459 452 452 MET MET D . n 
D 1 460 ARG 460 453 453 ARG ARG D . n 
D 1 461 VAL 461 454 454 VAL VAL D . n 
D 1 462 SER 462 455 455 SER SER D . n 
D 1 463 VAL 463 456 456 VAL VAL D . n 
D 1 464 GLU 464 457 457 GLU GLU D . n 
D 1 465 GLU 465 458 458 GLU GLU D . n 
D 1 466 ALA 466 459 459 ALA ALA D . n 
D 1 467 LEU 467 460 460 LEU LEU D . n 
D 1 468 GLU 468 461 461 GLU GLU D . n 
D 1 469 VAL 469 462 462 VAL VAL D . n 
D 1 470 SER 470 463 463 SER SER D . n 
D 1 471 ALA 471 464 464 ALA ALA D . n 
D 1 472 LYS 472 465 465 LYS LYS D . n 
D 1 473 GLU 473 466 466 GLU GLU D . n 
D 1 474 GLN 474 467 467 GLN GLN D . n 
D 1 475 GLN 475 468 468 GLN GLN D . n 
D 1 476 ASN 476 469 469 ASN ASN D . n 
D 1 477 ALA 477 470 470 ALA ALA D . n 
D 1 478 PHE 478 471 471 PHE PHE D . n 
D 1 479 TYR 479 472 472 TYR TYR D . n 
D 1 480 GLU 480 473 473 GLU GLU D . n 
D 1 481 ILE 481 474 474 ILE ILE D . n 
D 1 482 LEU 482 475 475 LEU LEU D . n 
D 1 483 HIS 483 476 476 HIS HIS D . n 
D 1 484 LEU 484 477 477 LEU LEU D . n 
D 1 485 PRO 485 478 478 PRO PRO D . n 
D 1 486 ASN 486 479 479 ASN ASN D . n 
D 1 487 LEU 487 480 480 LEU LEU D . n 
D 1 488 ASN 488 481 481 ASN ASN D . n 
D 1 489 GLU 489 482 482 GLU GLU D . n 
D 1 490 GLU 490 483 483 GLU GLU D . n 
D 1 491 GLN 491 484 484 GLN GLN D . n 
D 1 492 ARG 492 485 485 ARG ARG D . n 
D 1 493 ASN 493 486 486 ASN ASN D . n 
D 1 494 ALA 494 487 487 ALA ALA D . n 
D 1 495 PHE 495 488 488 PHE PHE D . n 
D 1 496 ILE 496 489 489 ILE ILE D . n 
D 1 497 GLN 497 490 490 GLN GLN D . n 
D 1 498 SER 498 491 491 SER SER D . n 
D 1 499 LEU 499 492 492 LEU LEU D . n 
D 1 500 LYS 500 493 493 LYS LYS D . n 
D 1 501 ASP 501 494 494 ASP ASP D . n 
D 1 502 ASP 502 495 495 ASP ASP D . n 
D 1 503 PRO 503 496 496 PRO PRO D . n 
D 1 504 SER 504 497 497 SER SER D . n 
D 1 505 GLN 505 498 498 GLN GLN D . n 
D 1 506 SER 506 499 499 SER SER D . n 
D 1 507 ALA 507 500 500 ALA ALA D . n 
D 1 508 ASN 508 501 501 ASN ASN D . n 
D 1 509 LEU 509 502 502 LEU LEU D . n 
D 1 510 LEU 510 503 503 LEU LEU D . n 
D 1 511 ALA 511 504 504 ALA ALA D . n 
D 1 512 GLU 512 505 505 GLU GLU D . n 
D 1 513 ALA 513 506 506 ALA ALA D . n 
D 1 514 LYS 514 507 507 LYS LYS D . n 
D 1 515 LYS 515 508 508 LYS LYS D . n 
D 1 516 LEU 516 509 509 LEU LEU D . n 
D 1 517 ASN 517 510 510 ASN ASN D . n 
D 1 518 ASP 518 511 511 ASP ASP D . n 
D 1 519 ALA 519 512 512 ALA ALA D . n 
D 1 520 GLN 520 513 513 GLN GLN D . n 
D 1 521 ALA 521 514 514 ALA ALA D . n 
D 1 522 PRO 522 515 ?   ?   ?   D . n 
D 1 523 LYS 523 516 ?   ?   ?   D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 PLP 1   601  601  PLP PLP A . 
F 2 PLP 1   601  601  PLP PLP B . 
G 2 PLP 1   601  601  PLP PLP C . 
H 2 PLP 1   601  601  PLP PLP D . 
I 3 HOH 1   701  171  HOH HOH A . 
I 3 HOH 2   702  97   HOH HOH A . 
I 3 HOH 3   703  204  HOH HOH A . 
I 3 HOH 4   704  156  HOH HOH A . 
I 3 HOH 5   705  1271 HOH HOH A . 
I 3 HOH 6   706  120  HOH HOH A . 
I 3 HOH 7   707  30   HOH HOH A . 
I 3 HOH 8   708  42   HOH HOH A . 
I 3 HOH 9   709  57   HOH HOH A . 
I 3 HOH 10  710  201  HOH HOH A . 
I 3 HOH 11  711  1403 HOH HOH A . 
I 3 HOH 12  712  1421 HOH HOH A . 
I 3 HOH 13  713  312  HOH HOH A . 
I 3 HOH 14  714  1211 HOH HOH A . 
I 3 HOH 15  715  1346 HOH HOH A . 
I 3 HOH 16  716  3    HOH HOH A . 
I 3 HOH 17  717  149  HOH HOH A . 
I 3 HOH 18  718  80   HOH HOH A . 
I 3 HOH 19  719  167  HOH HOH A . 
I 3 HOH 20  720  58   HOH HOH A . 
I 3 HOH 21  721  13   HOH HOH A . 
I 3 HOH 22  722  1269 HOH HOH A . 
I 3 HOH 23  723  158  HOH HOH A . 
I 3 HOH 24  724  11   HOH HOH A . 
I 3 HOH 25  725  67   HOH HOH A . 
I 3 HOH 26  726  91   HOH HOH A . 
I 3 HOH 27  727  39   HOH HOH A . 
I 3 HOH 28  728  367  HOH HOH A . 
I 3 HOH 29  729  173  HOH HOH A . 
I 3 HOH 30  730  109  HOH HOH A . 
I 3 HOH 31  731  106  HOH HOH A . 
I 3 HOH 32  732  124  HOH HOH A . 
I 3 HOH 33  733  1219 HOH HOH A . 
I 3 HOH 34  734  212  HOH HOH A . 
I 3 HOH 35  735  157  HOH HOH A . 
I 3 HOH 36  736  1435 HOH HOH A . 
I 3 HOH 37  737  1487 HOH HOH A . 
I 3 HOH 38  738  214  HOH HOH A . 
I 3 HOH 39  739  287  HOH HOH A . 
I 3 HOH 40  740  1452 HOH HOH A . 
I 3 HOH 41  741  209  HOH HOH A . 
I 3 HOH 42  742  272  HOH HOH A . 
I 3 HOH 43  743  261  HOH HOH A . 
I 3 HOH 44  744  113  HOH HOH A . 
I 3 HOH 45  745  186  HOH HOH A . 
I 3 HOH 46  746  183  HOH HOH A . 
I 3 HOH 47  747  1266 HOH HOH A . 
I 3 HOH 48  748  68   HOH HOH A . 
I 3 HOH 49  749  358  HOH HOH A . 
I 3 HOH 50  750  143  HOH HOH A . 
I 3 HOH 51  751  4    HOH HOH A . 
I 3 HOH 52  752  263  HOH HOH A . 
I 3 HOH 53  753  69   HOH HOH A . 
I 3 HOH 54  754  60   HOH HOH A . 
I 3 HOH 55  755  1402 HOH HOH A . 
I 3 HOH 56  756  34   HOH HOH A . 
I 3 HOH 57  757  154  HOH HOH A . 
I 3 HOH 58  758  253  HOH HOH A . 
I 3 HOH 59  759  258  HOH HOH A . 
I 3 HOH 60  760  8    HOH HOH A . 
I 3 HOH 61  761  107  HOH HOH A . 
I 3 HOH 62  762  136  HOH HOH A . 
I 3 HOH 63  763  64   HOH HOH A . 
I 3 HOH 64  764  83   HOH HOH A . 
I 3 HOH 65  765  1233 HOH HOH A . 
I 3 HOH 66  766  210  HOH HOH A . 
I 3 HOH 67  767  48   HOH HOH A . 
I 3 HOH 68  768  1304 HOH HOH A . 
I 3 HOH 69  769  1463 HOH HOH A . 
I 3 HOH 70  770  38   HOH HOH A . 
I 3 HOH 71  771  92   HOH HOH A . 
I 3 HOH 72  772  1173 HOH HOH A . 
I 3 HOH 73  773  1260 HOH HOH A . 
I 3 HOH 74  774  1308 HOH HOH A . 
I 3 HOH 75  775  21   HOH HOH A . 
I 3 HOH 76  776  172  HOH HOH A . 
I 3 HOH 77  777  1172 HOH HOH A . 
I 3 HOH 78  778  1272 HOH HOH A . 
I 3 HOH 79  779  52   HOH HOH A . 
I 3 HOH 80  780  50   HOH HOH A . 
I 3 HOH 81  781  65   HOH HOH A . 
I 3 HOH 82  782  82   HOH HOH A . 
I 3 HOH 83  783  118  HOH HOH A . 
I 3 HOH 84  784  137  HOH HOH A . 
I 3 HOH 85  785  195  HOH HOH A . 
I 3 HOH 86  786  163  HOH HOH A . 
I 3 HOH 87  787  301  HOH HOH A . 
I 3 HOH 88  788  6    HOH HOH A . 
I 3 HOH 89  789  81   HOH HOH A . 
I 3 HOH 90  790  100  HOH HOH A . 
I 3 HOH 91  791  22   HOH HOH A . 
I 3 HOH 92  792  24   HOH HOH A . 
I 3 HOH 93  793  17   HOH HOH A . 
I 3 HOH 94  794  15   HOH HOH A . 
I 3 HOH 95  795  1    HOH HOH A . 
I 3 HOH 96  796  61   HOH HOH A . 
I 3 HOH 97  797  1451 HOH HOH A . 
I 3 HOH 98  798  46   HOH HOH A . 
I 3 HOH 99  799  244  HOH HOH A . 
I 3 HOH 100 800  62   HOH HOH A . 
I 3 HOH 101 801  87   HOH HOH A . 
I 3 HOH 102 802  145  HOH HOH A . 
I 3 HOH 103 803  202  HOH HOH A . 
I 3 HOH 104 804  221  HOH HOH A . 
I 3 HOH 105 805  1468 HOH HOH A . 
I 3 HOH 106 806  196  HOH HOH A . 
I 3 HOH 107 807  94   HOH HOH A . 
I 3 HOH 108 808  101  HOH HOH A . 
I 3 HOH 109 809  256  HOH HOH A . 
I 3 HOH 110 810  270  HOH HOH A . 
I 3 HOH 111 811  47   HOH HOH A . 
I 3 HOH 112 812  265  HOH HOH A . 
I 3 HOH 113 813  51   HOH HOH A . 
I 3 HOH 114 814  148  HOH HOH A . 
I 3 HOH 115 815  19   HOH HOH A . 
I 3 HOH 116 816  37   HOH HOH A . 
I 3 HOH 117 817  228  HOH HOH A . 
I 3 HOH 118 818  144  HOH HOH A . 
I 3 HOH 119 819  89   HOH HOH A . 
I 3 HOH 120 820  102  HOH HOH A . 
I 3 HOH 121 821  12   HOH HOH A . 
I 3 HOH 122 822  28   HOH HOH A . 
I 3 HOH 123 823  10   HOH HOH A . 
I 3 HOH 124 824  231  HOH HOH A . 
I 3 HOH 125 825  236  HOH HOH A . 
I 3 HOH 126 826  355  HOH HOH A . 
I 3 HOH 127 827  77   HOH HOH A . 
I 3 HOH 128 828  119  HOH HOH A . 
I 3 HOH 129 829  189  HOH HOH A . 
I 3 HOH 130 830  1244 HOH HOH A . 
I 3 HOH 131 831  184  HOH HOH A . 
I 3 HOH 132 832  1298 HOH HOH A . 
I 3 HOH 133 833  504  HOH HOH A . 
I 3 HOH 134 834  99   HOH HOH A . 
I 3 HOH 135 835  1458 HOH HOH A . 
I 3 HOH 136 836  116  HOH HOH A . 
I 3 HOH 137 837  251  HOH HOH A . 
I 3 HOH 138 838  132  HOH HOH A . 
I 3 HOH 139 839  1181 HOH HOH A . 
I 3 HOH 140 840  7    HOH HOH A . 
I 3 HOH 141 841  1230 HOH HOH A . 
I 3 HOH 142 842  147  HOH HOH A . 
I 3 HOH 143 843  239  HOH HOH A . 
I 3 HOH 144 844  26   HOH HOH A . 
I 3 HOH 145 845  1312 HOH HOH A . 
I 3 HOH 146 846  35   HOH HOH A . 
I 3 HOH 147 847  180  HOH HOH A . 
I 3 HOH 148 848  243  HOH HOH A . 
I 3 HOH 149 849  29   HOH HOH A . 
I 3 HOH 150 850  1469 HOH HOH A . 
I 3 HOH 151 851  138  HOH HOH A . 
I 3 HOH 152 852  27   HOH HOH A . 
I 3 HOH 153 853  1384 HOH HOH A . 
I 3 HOH 154 854  190  HOH HOH A . 
I 3 HOH 155 855  127  HOH HOH A . 
I 3 HOH 156 856  66   HOH HOH A . 
I 3 HOH 157 857  262  HOH HOH A . 
I 3 HOH 158 858  1288 HOH HOH A . 
I 3 HOH 159 859  73   HOH HOH A . 
I 3 HOH 160 860  1390 HOH HOH A . 
I 3 HOH 161 861  108  HOH HOH A . 
I 3 HOH 162 862  41   HOH HOH A . 
I 3 HOH 163 863  18   HOH HOH A . 
I 3 HOH 164 864  2    HOH HOH A . 
I 3 HOH 165 865  74   HOH HOH A . 
I 3 HOH 166 866  84   HOH HOH A . 
I 3 HOH 167 867  33   HOH HOH A . 
I 3 HOH 168 868  193  HOH HOH A . 
I 3 HOH 169 869  249  HOH HOH A . 
I 3 HOH 170 870  14   HOH HOH A . 
I 3 HOH 171 871  264  HOH HOH A . 
I 3 HOH 172 872  20   HOH HOH A . 
I 3 HOH 173 873  72   HOH HOH A . 
I 3 HOH 174 874  5    HOH HOH A . 
I 3 HOH 175 875  246  HOH HOH A . 
I 3 HOH 176 876  1364 HOH HOH A . 
I 3 HOH 177 877  174  HOH HOH A . 
I 3 HOH 178 878  40   HOH HOH A . 
I 3 HOH 179 879  222  HOH HOH A . 
I 3 HOH 180 880  166  HOH HOH A . 
I 3 HOH 181 881  234  HOH HOH A . 
I 3 HOH 182 882  1481 HOH HOH A . 
I 3 HOH 183 883  188  HOH HOH A . 
I 3 HOH 184 884  16   HOH HOH A . 
I 3 HOH 185 885  123  HOH HOH A . 
I 3 HOH 186 886  1282 HOH HOH A . 
I 3 HOH 187 887  59   HOH HOH A . 
I 3 HOH 188 888  229  HOH HOH A . 
I 3 HOH 189 889  1361 HOH HOH A . 
I 3 HOH 190 890  227  HOH HOH A . 
I 3 HOH 191 891  1196 HOH HOH A . 
I 3 HOH 192 892  63   HOH HOH A . 
I 3 HOH 193 893  104  HOH HOH A . 
I 3 HOH 194 894  71   HOH HOH A . 
I 3 HOH 195 895  153  HOH HOH A . 
I 3 HOH 196 896  140  HOH HOH A . 
I 3 HOH 197 897  31   HOH HOH A . 
I 3 HOH 198 898  44   HOH HOH A . 
I 3 HOH 199 899  1158 HOH HOH A . 
I 3 HOH 200 900  43   HOH HOH A . 
I 3 HOH 201 901  54   HOH HOH A . 
I 3 HOH 202 902  192  HOH HOH A . 
I 3 HOH 203 903  242  HOH HOH A . 
I 3 HOH 204 904  105  HOH HOH A . 
I 3 HOH 205 905  206  HOH HOH A . 
I 3 HOH 206 906  1363 HOH HOH A . 
I 3 HOH 207 907  55   HOH HOH A . 
I 3 HOH 208 908  75   HOH HOH A . 
I 3 HOH 209 909  93   HOH HOH A . 
I 3 HOH 210 910  56   HOH HOH A . 
I 3 HOH 211 911  23   HOH HOH A . 
I 3 HOH 212 912  1144 HOH HOH A . 
I 3 HOH 213 913  150  HOH HOH A . 
I 3 HOH 214 914  292  HOH HOH A . 
I 3 HOH 215 915  130  HOH HOH A . 
I 3 HOH 216 916  259  HOH HOH A . 
I 3 HOH 217 917  203  HOH HOH A . 
I 3 HOH 218 918  128  HOH HOH A . 
I 3 HOH 219 919  1283 HOH HOH A . 
I 3 HOH 220 920  1314 HOH HOH A . 
I 3 HOH 221 921  1450 HOH HOH A . 
I 3 HOH 222 922  1388 HOH HOH A . 
I 3 HOH 223 923  88   HOH HOH A . 
I 3 HOH 224 924  1195 HOH HOH A . 
I 3 HOH 225 925  1335 HOH HOH A . 
I 3 HOH 226 926  1092 HOH HOH A . 
I 3 HOH 227 927  237  HOH HOH A . 
I 3 HOH 228 928  245  HOH HOH A . 
I 3 HOH 229 929  1350 HOH HOH A . 
I 3 HOH 230 930  364  HOH HOH A . 
I 3 HOH 231 931  1416 HOH HOH A . 
I 3 HOH 232 932  45   HOH HOH A . 
I 3 HOH 233 933  86   HOH HOH A . 
I 3 HOH 234 934  226  HOH HOH A . 
I 3 HOH 235 935  198  HOH HOH A . 
I 3 HOH 236 936  142  HOH HOH A . 
I 3 HOH 237 937  1278 HOH HOH A . 
I 3 HOH 238 938  1502 HOH HOH A . 
I 3 HOH 239 939  129  HOH HOH A . 
I 3 HOH 240 940  36   HOH HOH A . 
I 3 HOH 241 941  117  HOH HOH A . 
I 3 HOH 242 942  133  HOH HOH A . 
I 3 HOH 243 943  1360 HOH HOH A . 
I 3 HOH 244 944  1223 HOH HOH A . 
I 3 HOH 245 945  1204 HOH HOH A . 
I 3 HOH 246 946  161  HOH HOH A . 
I 3 HOH 247 947  1336 HOH HOH A . 
I 3 HOH 248 948  185  HOH HOH A . 
I 3 HOH 249 949  250  HOH HOH A . 
I 3 HOH 250 950  219  HOH HOH A . 
I 3 HOH 251 951  1292 HOH HOH A . 
I 3 HOH 252 952  267  HOH HOH A . 
I 3 HOH 253 953  1147 HOH HOH A . 
I 3 HOH 254 954  252  HOH HOH A . 
I 3 HOH 255 955  1359 HOH HOH A . 
I 3 HOH 256 956  1394 HOH HOH A . 
I 3 HOH 257 957  1277 HOH HOH A . 
I 3 HOH 258 958  224  HOH HOH A . 
I 3 HOH 259 959  111  HOH HOH A . 
I 3 HOH 260 960  232  HOH HOH A . 
I 3 HOH 261 961  200  HOH HOH A . 
I 3 HOH 262 962  218  HOH HOH A . 
I 3 HOH 263 963  1227 HOH HOH A . 
I 3 HOH 264 964  223  HOH HOH A . 
I 3 HOH 265 965  254  HOH HOH A . 
I 3 HOH 266 966  1014 HOH HOH A . 
I 3 HOH 267 967  205  HOH HOH A . 
I 3 HOH 268 968  1417 HOH HOH A . 
I 3 HOH 269 969  220  HOH HOH A . 
I 3 HOH 270 970  837  HOH HOH A . 
I 3 HOH 271 971  160  HOH HOH A . 
I 3 HOH 272 972  155  HOH HOH A . 
I 3 HOH 273 973  139  HOH HOH A . 
I 3 HOH 274 974  170  HOH HOH A . 
I 3 HOH 275 975  233  HOH HOH A . 
I 3 HOH 276 976  1494 HOH HOH A . 
I 3 HOH 277 977  176  HOH HOH A . 
I 3 HOH 278 978  217  HOH HOH A . 
I 3 HOH 279 979  211  HOH HOH A . 
I 3 HOH 280 980  125  HOH HOH A . 
I 3 HOH 281 981  1184 HOH HOH A . 
I 3 HOH 282 982  225  HOH HOH A . 
I 3 HOH 283 983  213  HOH HOH A . 
I 3 HOH 284 984  1330 HOH HOH A . 
I 3 HOH 285 985  182  HOH HOH A . 
I 3 HOH 286 986  78   HOH HOH A . 
I 3 HOH 287 987  103  HOH HOH A . 
I 3 HOH 288 988  168  HOH HOH A . 
I 3 HOH 289 989  1319 HOH HOH A . 
I 3 HOH 290 990  175  HOH HOH A . 
I 3 HOH 291 991  159  HOH HOH A . 
I 3 HOH 292 992  257  HOH HOH A . 
I 3 HOH 293 993  112  HOH HOH A . 
I 3 HOH 294 994  165  HOH HOH A . 
I 3 HOH 295 995  1392 HOH HOH A . 
I 3 HOH 296 996  121  HOH HOH A . 
I 3 HOH 297 997  215  HOH HOH A . 
I 3 HOH 298 998  70   HOH HOH A . 
I 3 HOH 299 999  199  HOH HOH A . 
I 3 HOH 300 1000 235  HOH HOH A . 
I 3 HOH 301 1001 266  HOH HOH A . 
I 3 HOH 302 1002 187  HOH HOH A . 
I 3 HOH 303 1003 114  HOH HOH A . 
I 3 HOH 304 1004 241  HOH HOH A . 
I 3 HOH 305 1005 354  HOH HOH A . 
I 3 HOH 306 1006 96   HOH HOH A . 
I 3 HOH 307 1007 230  HOH HOH A . 
I 3 HOH 308 1008 260  HOH HOH A . 
I 3 HOH 309 1009 1325 HOH HOH A . 
I 3 HOH 310 1010 25   HOH HOH A . 
I 3 HOH 311 1011 1142 HOH HOH A . 
I 3 HOH 312 1012 1430 HOH HOH A . 
I 3 HOH 313 1013 194  HOH HOH A . 
I 3 HOH 314 1014 110  HOH HOH A . 
I 3 HOH 315 1015 485  HOH HOH A . 
I 3 HOH 316 1016 463  HOH HOH A . 
I 3 HOH 317 1017 1382 HOH HOH A . 
I 3 HOH 318 1018 1159 HOH HOH A . 
I 3 HOH 319 1019 151  HOH HOH A . 
I 3 HOH 320 1020 216  HOH HOH A . 
I 3 HOH 321 1021 1139 HOH HOH A . 
I 3 HOH 322 1022 179  HOH HOH A . 
I 3 HOH 323 1023 1222 HOH HOH A . 
I 3 HOH 324 1024 146  HOH HOH A . 
I 3 HOH 325 1025 247  HOH HOH A . 
I 3 HOH 326 1026 162  HOH HOH A . 
I 3 HOH 327 1027 49   HOH HOH A . 
I 3 HOH 328 1028 1213 HOH HOH A . 
I 3 HOH 329 1029 1385 HOH HOH A . 
I 3 HOH 330 1030 95   HOH HOH A . 
I 3 HOH 331 1031 181  HOH HOH A . 
I 3 HOH 332 1032 1426 HOH HOH A . 
I 3 HOH 333 1033 1274 HOH HOH A . 
I 3 HOH 334 1034 1183 HOH HOH A . 
I 3 HOH 335 1035 1264 HOH HOH A . 
I 3 HOH 336 1036 134  HOH HOH A . 
I 3 HOH 337 1037 1286 HOH HOH A . 
I 3 HOH 338 1038 141  HOH HOH A . 
I 3 HOH 339 1039 90   HOH HOH A . 
I 3 HOH 340 1040 1377 HOH HOH A . 
I 3 HOH 341 1041 1329 HOH HOH A . 
I 3 HOH 342 1042 248  HOH HOH A . 
I 3 HOH 343 1043 177  HOH HOH A . 
I 3 HOH 344 1044 1303 HOH HOH A . 
I 3 HOH 345 1045 255  HOH HOH A . 
I 3 HOH 346 1046 1344 HOH HOH A . 
J 3 HOH 1   701  1210 HOH HOH B . 
J 3 HOH 2   702  512  HOH HOH B . 
J 3 HOH 3   703  322  HOH HOH B . 
J 3 HOH 4   704  490  HOH HOH B . 
J 3 HOH 5   705  383  HOH HOH B . 
J 3 HOH 6   706  348  HOH HOH B . 
J 3 HOH 7   707  282  HOH HOH B . 
J 3 HOH 8   708  345  HOH HOH B . 
J 3 HOH 9   709  331  HOH HOH B . 
J 3 HOH 10  710  458  HOH HOH B . 
J 3 HOH 11  711  1488 HOH HOH B . 
J 3 HOH 12  712  1368 HOH HOH B . 
J 3 HOH 13  713  382  HOH HOH B . 
J 3 HOH 14  714  524  HOH HOH B . 
J 3 HOH 15  715  1467 HOH HOH B . 
J 3 HOH 16  716  407  HOH HOH B . 
J 3 HOH 17  717  288  HOH HOH B . 
J 3 HOH 18  718  317  HOH HOH B . 
J 3 HOH 19  719  327  HOH HOH B . 
J 3 HOH 20  720  457  HOH HOH B . 
J 3 HOH 21  721  308  HOH HOH B . 
J 3 HOH 22  722  473  HOH HOH B . 
J 3 HOH 23  723  416  HOH HOH B . 
J 3 HOH 24  724  279  HOH HOH B . 
J 3 HOH 25  725  409  HOH HOH B . 
J 3 HOH 26  726  1356 HOH HOH B . 
J 3 HOH 27  727  1155 HOH HOH B . 
J 3 HOH 28  728  356  HOH HOH B . 
J 3 HOH 29  729  529  HOH HOH B . 
J 3 HOH 30  730  315  HOH HOH B . 
J 3 HOH 31  731  1371 HOH HOH B . 
J 3 HOH 32  732  276  HOH HOH B . 
J 3 HOH 33  733  393  HOH HOH B . 
J 3 HOH 34  734  1459 HOH HOH B . 
J 3 HOH 35  735  469  HOH HOH B . 
J 3 HOH 36  736  536  HOH HOH B . 
J 3 HOH 37  737  1153 HOH HOH B . 
J 3 HOH 38  738  1225 HOH HOH B . 
J 3 HOH 39  739  447  HOH HOH B . 
J 3 HOH 40  740  564  HOH HOH B . 
J 3 HOH 41  741  1220 HOH HOH B . 
J 3 HOH 42  742  274  HOH HOH B . 
J 3 HOH 43  743  275  HOH HOH B . 
J 3 HOH 44  744  561  HOH HOH B . 
J 3 HOH 45  745  448  HOH HOH B . 
J 3 HOH 46  746  391  HOH HOH B . 
J 3 HOH 47  747  328  HOH HOH B . 
J 3 HOH 48  748  1482 HOH HOH B . 
J 3 HOH 49  749  363  HOH HOH B . 
J 3 HOH 50  750  557  HOH HOH B . 
J 3 HOH 51  751  326  HOH HOH B . 
J 3 HOH 52  752  426  HOH HOH B . 
J 3 HOH 53  753  291  HOH HOH B . 
J 3 HOH 54  754  466  HOH HOH B . 
J 3 HOH 55  755  349  HOH HOH B . 
J 3 HOH 56  756  481  HOH HOH B . 
J 3 HOH 57  757  1150 HOH HOH B . 
J 3 HOH 58  758  403  HOH HOH B . 
J 3 HOH 59  759  563  HOH HOH B . 
J 3 HOH 60  760  341  HOH HOH B . 
J 3 HOH 61  761  361  HOH HOH B . 
J 3 HOH 62  762  1496 HOH HOH B . 
J 3 HOH 63  763  1290 HOH HOH B . 
J 3 HOH 64  764  427  HOH HOH B . 
J 3 HOH 65  765  309  HOH HOH B . 
J 3 HOH 66  766  402  HOH HOH B . 
J 3 HOH 67  767  449  HOH HOH B . 
J 3 HOH 68  768  482  HOH HOH B . 
J 3 HOH 69  769  1399 HOH HOH B . 
J 3 HOH 70  770  299  HOH HOH B . 
J 3 HOH 71  771  1251 HOH HOH B . 
J 3 HOH 72  772  401  HOH HOH B . 
J 3 HOH 73  773  386  HOH HOH B . 
J 3 HOH 74  774  373  HOH HOH B . 
J 3 HOH 75  775  1466 HOH HOH B . 
J 3 HOH 76  776  122  HOH HOH B . 
J 3 HOH 77  777  396  HOH HOH B . 
J 3 HOH 78  778  32   HOH HOH B . 
J 3 HOH 79  779  444  HOH HOH B . 
J 3 HOH 80  780  351  HOH HOH B . 
J 3 HOH 81  781  362  HOH HOH B . 
J 3 HOH 82  782  470  HOH HOH B . 
J 3 HOH 83  783  305  HOH HOH B . 
J 3 HOH 84  784  283  HOH HOH B . 
J 3 HOH 85  785  417  HOH HOH B . 
J 3 HOH 86  786  421  HOH HOH B . 
J 3 HOH 87  787  311  HOH HOH B . 
J 3 HOH 88  788  1461 HOH HOH B . 
J 3 HOH 89  789  377  HOH HOH B . 
J 3 HOH 90  790  9    HOH HOH B . 
J 3 HOH 91  791  314  HOH HOH B . 
J 3 HOH 92  792  300  HOH HOH B . 
J 3 HOH 93  793  384  HOH HOH B . 
J 3 HOH 94  794  339  HOH HOH B . 
J 3 HOH 95  795  380  HOH HOH B . 
J 3 HOH 96  796  310  HOH HOH B . 
J 3 HOH 97  797  350  HOH HOH B . 
J 3 HOH 98  798  1146 HOH HOH B . 
J 3 HOH 99  799  53   HOH HOH B . 
J 3 HOH 100 800  1429 HOH HOH B . 
J 3 HOH 101 801  359  HOH HOH B . 
J 3 HOH 102 802  443  HOH HOH B . 
J 3 HOH 103 803  325  HOH HOH B . 
J 3 HOH 104 804  545  HOH HOH B . 
J 3 HOH 105 805  425  HOH HOH B . 
J 3 HOH 106 806  336  HOH HOH B . 
J 3 HOH 107 807  340  HOH HOH B . 
J 3 HOH 108 808  290  HOH HOH B . 
J 3 HOH 109 809  289  HOH HOH B . 
J 3 HOH 110 810  333  HOH HOH B . 
J 3 HOH 111 811  1257 HOH HOH B . 
J 3 HOH 112 812  1407 HOH HOH B . 
J 3 HOH 113 813  479  HOH HOH B . 
J 3 HOH 114 814  313  HOH HOH B . 
J 3 HOH 115 815  406  HOH HOH B . 
J 3 HOH 116 816  76   HOH HOH B . 
J 3 HOH 117 817  548  HOH HOH B . 
J 3 HOH 118 818  1457 HOH HOH B . 
J 3 HOH 119 819  381  HOH HOH B . 
J 3 HOH 120 820  1367 HOH HOH B . 
J 3 HOH 121 821  303  HOH HOH B . 
J 3 HOH 122 822  763  HOH HOH B . 
J 3 HOH 123 823  1262 HOH HOH B . 
J 3 HOH 124 824  553  HOH HOH B . 
J 3 HOH 125 825  344  HOH HOH B . 
J 3 HOH 126 826  334  HOH HOH B . 
J 3 HOH 127 827  284  HOH HOH B . 
J 3 HOH 128 828  519  HOH HOH B . 
J 3 HOH 129 829  476  HOH HOH B . 
J 3 HOH 130 830  419  HOH HOH B . 
J 3 HOH 131 831  294  HOH HOH B . 
J 3 HOH 132 832  302  HOH HOH B . 
J 3 HOH 133 833  281  HOH HOH B . 
J 3 HOH 134 834  298  HOH HOH B . 
J 3 HOH 135 835  321  HOH HOH B . 
J 3 HOH 136 836  488  HOH HOH B . 
J 3 HOH 137 837  85   HOH HOH B . 
J 3 HOH 138 838  318  HOH HOH B . 
J 3 HOH 139 839  353  HOH HOH B . 
J 3 HOH 140 840  541  HOH HOH B . 
J 3 HOH 141 841  285  HOH HOH B . 
J 3 HOH 142 842  271  HOH HOH B . 
J 3 HOH 143 843  304  HOH HOH B . 
J 3 HOH 144 844  319  HOH HOH B . 
J 3 HOH 145 845  295  HOH HOH B . 
J 3 HOH 146 846  411  HOH HOH B . 
J 3 HOH 147 847  511  HOH HOH B . 
J 3 HOH 148 848  1485 HOH HOH B . 
J 3 HOH 149 849  456  HOH HOH B . 
J 3 HOH 150 850  1151 HOH HOH B . 
J 3 HOH 151 851  547  HOH HOH B . 
J 3 HOH 152 852  487  HOH HOH B . 
J 3 HOH 153 853  296  HOH HOH B . 
J 3 HOH 154 854  1491 HOH HOH B . 
J 3 HOH 155 855  560  HOH HOH B . 
J 3 HOH 156 856  400  HOH HOH B . 
J 3 HOH 157 857  462  HOH HOH B . 
J 3 HOH 158 858  306  HOH HOH B . 
J 3 HOH 159 859  537  HOH HOH B . 
J 3 HOH 160 860  527  HOH HOH B . 
J 3 HOH 161 861  1161 HOH HOH B . 
J 3 HOH 162 862  523  HOH HOH B . 
J 3 HOH 163 863  379  HOH HOH B . 
J 3 HOH 164 864  320  HOH HOH B . 
J 3 HOH 165 865  286  HOH HOH B . 
J 3 HOH 166 866  297  HOH HOH B . 
J 3 HOH 167 867  280  HOH HOH B . 
J 3 HOH 168 868  269  HOH HOH B . 
J 3 HOH 169 869  1324 HOH HOH B . 
J 3 HOH 170 870  418  HOH HOH B . 
J 3 HOH 171 871  565  HOH HOH B . 
J 3 HOH 172 872  501  HOH HOH B . 
J 3 HOH 173 873  368  HOH HOH B . 
J 3 HOH 174 874  412  HOH HOH B . 
J 3 HOH 175 875  439  HOH HOH B . 
J 3 HOH 176 876  332  HOH HOH B . 
J 3 HOH 177 877  342  HOH HOH B . 
J 3 HOH 178 878  420  HOH HOH B . 
J 3 HOH 179 879  394  HOH HOH B . 
J 3 HOH 180 880  559  HOH HOH B . 
J 3 HOH 181 881  1209 HOH HOH B . 
J 3 HOH 182 882  1419 HOH HOH B . 
J 3 HOH 183 883  389  HOH HOH B . 
J 3 HOH 184 884  492  HOH HOH B . 
J 3 HOH 185 885  413  HOH HOH B . 
J 3 HOH 186 886  558  HOH HOH B . 
J 3 HOH 187 887  273  HOH HOH B . 
J 3 HOH 188 888  337  HOH HOH B . 
J 3 HOH 189 889  372  HOH HOH B . 
J 3 HOH 190 890  1498 HOH HOH B . 
J 3 HOH 191 891  238  HOH HOH B . 
J 3 HOH 192 892  307  HOH HOH B . 
J 3 HOH 193 893  278  HOH HOH B . 
J 3 HOH 194 894  452  HOH HOH B . 
J 3 HOH 195 895  494  HOH HOH B . 
J 3 HOH 196 896  450  HOH HOH B . 
J 3 HOH 197 897  543  HOH HOH B . 
J 3 HOH 198 898  546  HOH HOH B . 
J 3 HOH 199 899  467  HOH HOH B . 
J 3 HOH 200 900  115  HOH HOH B . 
J 3 HOH 201 901  346  HOH HOH B . 
J 3 HOH 202 902  431  HOH HOH B . 
J 3 HOH 203 903  535  HOH HOH B . 
J 3 HOH 204 904  508  HOH HOH B . 
J 3 HOH 205 905  1178 HOH HOH B . 
J 3 HOH 206 906  468  HOH HOH B . 
J 3 HOH 207 907  1351 HOH HOH B . 
J 3 HOH 208 908  277  HOH HOH B . 
J 3 HOH 209 909  532  HOH HOH B . 
J 3 HOH 210 910  438  HOH HOH B . 
J 3 HOH 211 911  437  HOH HOH B . 
J 3 HOH 212 912  1201 HOH HOH B . 
J 3 HOH 213 913  480  HOH HOH B . 
J 3 HOH 214 914  1464 HOH HOH B . 
J 3 HOH 215 915  475  HOH HOH B . 
J 3 HOH 216 916  126  HOH HOH B . 
J 3 HOH 217 917  1389 HOH HOH B . 
J 3 HOH 218 918  1453 HOH HOH B . 
J 3 HOH 219 919  1420 HOH HOH B . 
J 3 HOH 220 920  1228 HOH HOH B . 
J 3 HOH 221 921  293  HOH HOH B . 
J 3 HOH 222 922  489  HOH HOH B . 
J 3 HOH 223 923  376  HOH HOH B . 
J 3 HOH 224 924  454  HOH HOH B . 
J 3 HOH 225 925  240  HOH HOH B . 
J 3 HOH 226 926  432  HOH HOH B . 
J 3 HOH 227 927  484  HOH HOH B . 
J 3 HOH 228 928  422  HOH HOH B . 
J 3 HOH 229 929  483  HOH HOH B . 
J 3 HOH 230 930  1318 HOH HOH B . 
J 3 HOH 231 931  1347 HOH HOH B . 
J 3 HOH 232 932  498  HOH HOH B . 
J 3 HOH 233 933  330  HOH HOH B . 
J 3 HOH 234 934  505  HOH HOH B . 
J 3 HOH 235 935  472  HOH HOH B . 
J 3 HOH 236 936  442  HOH HOH B . 
J 3 HOH 237 937  329  HOH HOH B . 
J 3 HOH 238 938  797  HOH HOH B . 
J 3 HOH 239 939  436  HOH HOH B . 
J 3 HOH 240 940  515  HOH HOH B . 
J 3 HOH 241 941  1327 HOH HOH B . 
J 3 HOH 242 942  392  HOH HOH B . 
J 3 HOH 243 943  1231 HOH HOH B . 
J 3 HOH 244 944  1197 HOH HOH B . 
J 3 HOH 245 945  390  HOH HOH B . 
J 3 HOH 246 946  323  HOH HOH B . 
J 3 HOH 247 947  550  HOH HOH B . 
J 3 HOH 248 948  1149 HOH HOH B . 
J 3 HOH 249 949  387  HOH HOH B . 
J 3 HOH 250 950  410  HOH HOH B . 
J 3 HOH 251 951  347  HOH HOH B . 
J 3 HOH 252 952  371  HOH HOH B . 
J 3 HOH 253 953  1500 HOH HOH B . 
J 3 HOH 254 954  451  HOH HOH B . 
J 3 HOH 255 955  324  HOH HOH B . 
J 3 HOH 256 956  430  HOH HOH B . 
J 3 HOH 257 957  1341 HOH HOH B . 
J 3 HOH 258 958  357  HOH HOH B . 
J 3 HOH 259 959  522  HOH HOH B . 
J 3 HOH 260 960  477  HOH HOH B . 
J 3 HOH 261 961  542  HOH HOH B . 
J 3 HOH 262 962  1454 HOH HOH B . 
J 3 HOH 263 963  526  HOH HOH B . 
J 3 HOH 264 964  804  HOH HOH B . 
J 3 HOH 265 965  1505 HOH HOH B . 
J 3 HOH 266 966  516  HOH HOH B . 
J 3 HOH 267 967  495  HOH HOH B . 
J 3 HOH 268 968  433  HOH HOH B . 
J 3 HOH 269 969  335  HOH HOH B . 
J 3 HOH 270 970  434  HOH HOH B . 
J 3 HOH 271 971  1176 HOH HOH B . 
J 3 HOH 272 972  521  HOH HOH B . 
J 3 HOH 273 973  360  HOH HOH B . 
J 3 HOH 274 974  423  HOH HOH B . 
J 3 HOH 275 975  486  HOH HOH B . 
J 3 HOH 276 976  1206 HOH HOH B . 
J 3 HOH 277 977  1297 HOH HOH B . 
J 3 HOH 278 978  378  HOH HOH B . 
J 3 HOH 279 979  338  HOH HOH B . 
J 3 HOH 280 980  1432 HOH HOH B . 
J 3 HOH 281 981  540  HOH HOH B . 
J 3 HOH 282 982  1431 HOH HOH B . 
J 3 HOH 283 983  461  HOH HOH B . 
J 3 HOH 284 984  1217 HOH HOH B . 
J 3 HOH 285 985  1406 HOH HOH B . 
J 3 HOH 286 986  414  HOH HOH B . 
J 3 HOH 287 987  1265 HOH HOH B . 
J 3 HOH 288 988  555  HOH HOH B . 
J 3 HOH 289 989  445  HOH HOH B . 
J 3 HOH 290 990  1343 HOH HOH B . 
J 3 HOH 291 991  428  HOH HOH B . 
J 3 HOH 292 992  207  HOH HOH B . 
J 3 HOH 293 993  352  HOH HOH B . 
J 3 HOH 294 994  551  HOH HOH B . 
J 3 HOH 295 995  510  HOH HOH B . 
J 3 HOH 296 996  474  HOH HOH B . 
J 3 HOH 297 997  1358 HOH HOH B . 
J 3 HOH 298 998  1436 HOH HOH B . 
J 3 HOH 299 999  502  HOH HOH B . 
J 3 HOH 300 1000 568  HOH HOH B . 
J 3 HOH 301 1001 1354 HOH HOH B . 
J 3 HOH 302 1002 178  HOH HOH B . 
J 3 HOH 303 1003 453  HOH HOH B . 
J 3 HOH 304 1004 459  HOH HOH B . 
J 3 HOH 305 1005 1455 HOH HOH B . 
J 3 HOH 306 1006 440  HOH HOH B . 
J 3 HOH 307 1007 1174 HOH HOH B . 
J 3 HOH 308 1008 1355 HOH HOH B . 
J 3 HOH 309 1009 441  HOH HOH B . 
J 3 HOH 310 1010 525  HOH HOH B . 
J 3 HOH 311 1011 366  HOH HOH B . 
J 3 HOH 312 1012 552  HOH HOH B . 
J 3 HOH 313 1013 549  HOH HOH B . 
J 3 HOH 314 1014 1456 HOH HOH B . 
J 3 HOH 315 1015 1275 HOH HOH B . 
J 3 HOH 316 1016 268  HOH HOH B . 
J 3 HOH 317 1017 464  HOH HOH B . 
J 3 HOH 318 1018 1413 HOH HOH B . 
J 3 HOH 319 1019 98   HOH HOH B . 
J 3 HOH 320 1020 507  HOH HOH B . 
J 3 HOH 321 1021 1499 HOH HOH B . 
J 3 HOH 322 1022 1477 HOH HOH B . 
J 3 HOH 323 1023 531  HOH HOH B . 
J 3 HOH 324 1024 1221 HOH HOH B . 
J 3 HOH 325 1025 538  HOH HOH B . 
J 3 HOH 326 1026 478  HOH HOH B . 
J 3 HOH 327 1027 385  HOH HOH B . 
J 3 HOH 328 1028 503  HOH HOH B . 
J 3 HOH 329 1029 397  HOH HOH B . 
J 3 HOH 330 1030 460  HOH HOH B . 
J 3 HOH 331 1031 415  HOH HOH B . 
J 3 HOH 332 1032 465  HOH HOH B . 
J 3 HOH 333 1033 1433 HOH HOH B . 
J 3 HOH 334 1034 1291 HOH HOH B . 
J 3 HOH 335 1035 506  HOH HOH B . 
J 3 HOH 336 1036 533  HOH HOH B . 
J 3 HOH 337 1037 374  HOH HOH B . 
J 3 HOH 338 1038 429  HOH HOH B . 
J 3 HOH 339 1039 388  HOH HOH B . 
J 3 HOH 340 1040 1187 HOH HOH B . 
J 3 HOH 341 1041 370  HOH HOH B . 
J 3 HOH 342 1042 496  HOH HOH B . 
J 3 HOH 343 1043 1408 HOH HOH B . 
J 3 HOH 344 1044 1378 HOH HOH B . 
J 3 HOH 345 1045 1246 HOH HOH B . 
J 3 HOH 346 1046 208  HOH HOH B . 
J 3 HOH 347 1047 424  HOH HOH B . 
J 3 HOH 348 1048 556  HOH HOH B . 
J 3 HOH 349 1049 316  HOH HOH B . 
J 3 HOH 350 1050 566  HOH HOH B . 
J 3 HOH 351 1051 528  HOH HOH B . 
J 3 HOH 352 1052 518  HOH HOH B . 
J 3 HOH 353 1053 1258 HOH HOH B . 
J 3 HOH 354 1054 369  HOH HOH B . 
J 3 HOH 355 1055 395  HOH HOH B . 
J 3 HOH 356 1056 493  HOH HOH B . 
J 3 HOH 357 1057 1241 HOH HOH B . 
J 3 HOH 358 1058 398  HOH HOH B . 
J 3 HOH 359 1059 530  HOH HOH B . 
J 3 HOH 360 1060 544  HOH HOH B . 
J 3 HOH 361 1061 539  HOH HOH B . 
J 3 HOH 362 1062 520  HOH HOH B . 
J 3 HOH 363 1063 509  HOH HOH B . 
J 3 HOH 364 1064 711  HOH HOH B . 
J 3 HOH 365 1065 1310 HOH HOH B . 
J 3 HOH 366 1066 1478 HOH HOH B . 
J 3 HOH 367 1067 491  HOH HOH B . 
J 3 HOH 368 1068 1434 HOH HOH B . 
J 3 HOH 369 1069 408  HOH HOH B . 
J 3 HOH 370 1070 1338 HOH HOH B . 
J 3 HOH 371 1071 1348 HOH HOH B . 
J 3 HOH 372 1072 169  HOH HOH B . 
J 3 HOH 373 1073 534  HOH HOH B . 
J 3 HOH 374 1074 405  HOH HOH B . 
J 3 HOH 375 1075 1236 HOH HOH B . 
J 3 HOH 376 1076 1156 HOH HOH B . 
J 3 HOH 377 1077 1261 HOH HOH B . 
J 3 HOH 378 1078 1486 HOH HOH B . 
J 3 HOH 379 1079 399  HOH HOH B . 
J 3 HOH 380 1080 1202 HOH HOH B . 
J 3 HOH 381 1081 404  HOH HOH B . 
J 3 HOH 382 1082 446  HOH HOH B . 
J 3 HOH 383 1083 1135 HOH HOH B . 
J 3 HOH 384 1084 554  HOH HOH B . 
J 3 HOH 385 1085 500  HOH HOH B . 
J 3 HOH 386 1086 514  HOH HOH B . 
J 3 HOH 387 1087 1268 HOH HOH B . 
J 3 HOH 388 1088 513  HOH HOH B . 
J 3 HOH 389 1089 497  HOH HOH B . 
J 3 HOH 390 1090 1179 HOH HOH B . 
J 3 HOH 391 1091 365  HOH HOH B . 
J 3 HOH 392 1092 455  HOH HOH B . 
J 3 HOH 393 1093 1024 HOH HOH B . 
J 3 HOH 394 1094 375  HOH HOH B . 
J 3 HOH 395 1095 567  HOH HOH B . 
J 3 HOH 396 1096 435  HOH HOH B . 
J 3 HOH 397 1097 1396 HOH HOH B . 
J 3 HOH 398 1098 1152 HOH HOH B . 
J 3 HOH 399 1099 1381 HOH HOH B . 
J 3 HOH 400 1100 1501 HOH HOH B . 
J 3 HOH 401 1101 1423 HOH HOH B . 
J 3 HOH 402 1102 1370 HOH HOH B . 
J 3 HOH 403 1103 1398 HOH HOH B . 
J 3 HOH 404 1104 562  HOH HOH B . 
J 3 HOH 405 1105 1397 HOH HOH B . 
J 3 HOH 406 1106 499  HOH HOH B . 
K 3 HOH 1   701  716  HOH HOH C . 
K 3 HOH 2   702  607  HOH HOH C . 
K 3 HOH 3   703  780  HOH HOH C . 
K 3 HOH 4   704  706  HOH HOH C . 
K 3 HOH 5   705  818  HOH HOH C . 
K 3 HOH 6   706  674  HOH HOH C . 
K 3 HOH 7   707  641  HOH HOH C . 
K 3 HOH 8   708  601  HOH HOH C . 
K 3 HOH 9   709  620  HOH HOH C . 
K 3 HOH 10  710  840  HOH HOH C . 
K 3 HOH 11  711  732  HOH HOH C . 
K 3 HOH 12  712  1216 HOH HOH C . 
K 3 HOH 13  713  1248 HOH HOH C . 
K 3 HOH 14  714  703  HOH HOH C . 
K 3 HOH 15  715  778  HOH HOH C . 
K 3 HOH 16  716  644  HOH HOH C . 
K 3 HOH 17  717  823  HOH HOH C . 
K 3 HOH 18  718  1475 HOH HOH C . 
K 3 HOH 19  719  635  HOH HOH C . 
K 3 HOH 20  720  736  HOH HOH C . 
K 3 HOH 21  721  749  HOH HOH C . 
K 3 HOH 22  722  715  HOH HOH C . 
K 3 HOH 23  723  572  HOH HOH C . 
K 3 HOH 24  724  699  HOH HOH C . 
K 3 HOH 25  725  750  HOH HOH C . 
K 3 HOH 26  726  1299 HOH HOH C . 
K 3 HOH 27  727  628  HOH HOH C . 
K 3 HOH 28  728  714  HOH HOH C . 
K 3 HOH 29  729  581  HOH HOH C . 
K 3 HOH 30  730  725  HOH HOH C . 
K 3 HOH 31  731  615  HOH HOH C . 
K 3 HOH 32  732  678  HOH HOH C . 
K 3 HOH 33  733  656  HOH HOH C . 
K 3 HOH 34  734  764  HOH HOH C . 
K 3 HOH 35  735  720  HOH HOH C . 
K 3 HOH 36  736  654  HOH HOH C . 
K 3 HOH 37  737  610  HOH HOH C . 
K 3 HOH 38  738  593  HOH HOH C . 
K 3 HOH 39  739  694  HOH HOH C . 
K 3 HOH 40  740  671  HOH HOH C . 
K 3 HOH 41  741  648  HOH HOH C . 
K 3 HOH 42  742  570  HOH HOH C . 
K 3 HOH 43  743  576  HOH HOH C . 
K 3 HOH 44  744  640  HOH HOH C . 
K 3 HOH 45  745  719  HOH HOH C . 
K 3 HOH 46  746  651  HOH HOH C . 
K 3 HOH 47  747  1138 HOH HOH C . 
K 3 HOH 48  748  829  HOH HOH C . 
K 3 HOH 49  749  692  HOH HOH C . 
K 3 HOH 50  750  592  HOH HOH C . 
K 3 HOH 51  751  1255 HOH HOH C . 
K 3 HOH 52  752  1169 HOH HOH C . 
K 3 HOH 53  753  748  HOH HOH C . 
K 3 HOH 54  754  1422 HOH HOH C . 
K 3 HOH 55  755  1253 HOH HOH C . 
K 3 HOH 56  756  808  HOH HOH C . 
K 3 HOH 57  757  1366 HOH HOH C . 
K 3 HOH 58  758  790  HOH HOH C . 
K 3 HOH 59  759  744  HOH HOH C . 
K 3 HOH 60  760  612  HOH HOH C . 
K 3 HOH 61  761  603  HOH HOH C . 
K 3 HOH 62  762  730  HOH HOH C . 
K 3 HOH 63  763  573  HOH HOH C . 
K 3 HOH 64  764  1226 HOH HOH C . 
K 3 HOH 65  765  689  HOH HOH C . 
K 3 HOH 66  766  746  HOH HOH C . 
K 3 HOH 67  767  1400 HOH HOH C . 
K 3 HOH 68  768  585  HOH HOH C . 
K 3 HOH 69  769  1141 HOH HOH C . 
K 3 HOH 70  770  569  HOH HOH C . 
K 3 HOH 71  771  1441 HOH HOH C . 
K 3 HOH 72  772  1444 HOH HOH C . 
K 3 HOH 73  773  632  HOH HOH C . 
K 3 HOH 74  774  728  HOH HOH C . 
K 3 HOH 75  775  1247 HOH HOH C . 
K 3 HOH 76  776  630  HOH HOH C . 
K 3 HOH 77  777  812  HOH HOH C . 
K 3 HOH 78  778  662  HOH HOH C . 
K 3 HOH 79  779  821  HOH HOH C . 
K 3 HOH 80  780  636  HOH HOH C . 
K 3 HOH 81  781  1193 HOH HOH C . 
K 3 HOH 82  782  616  HOH HOH C . 
K 3 HOH 83  783  598  HOH HOH C . 
K 3 HOH 84  784  708  HOH HOH C . 
K 3 HOH 85  785  665  HOH HOH C . 
K 3 HOH 86  786  633  HOH HOH C . 
K 3 HOH 87  787  619  HOH HOH C . 
K 3 HOH 88  788  767  HOH HOH C . 
K 3 HOH 89  789  889  HOH HOH C . 
K 3 HOH 90  790  770  HOH HOH C . 
K 3 HOH 91  791  629  HOH HOH C . 
K 3 HOH 92  792  625  HOH HOH C . 
K 3 HOH 93  793  668  HOH HOH C . 
K 3 HOH 94  794  773  HOH HOH C . 
K 3 HOH 95  795  574  HOH HOH C . 
K 3 HOH 96  796  600  HOH HOH C . 
K 3 HOH 97  797  751  HOH HOH C . 
K 3 HOH 98  798  591  HOH HOH C . 
K 3 HOH 99  799  652  HOH HOH C . 
K 3 HOH 100 800  704  HOH HOH C . 
K 3 HOH 101 801  587  HOH HOH C . 
K 3 HOH 102 802  1171 HOH HOH C . 
K 3 HOH 103 803  609  HOH HOH C . 
K 3 HOH 104 804  599  HOH HOH C . 
K 3 HOH 105 805  602  HOH HOH C . 
K 3 HOH 106 806  583  HOH HOH C . 
K 3 HOH 107 807  617  HOH HOH C . 
K 3 HOH 108 808  575  HOH HOH C . 
K 3 HOH 109 809  643  HOH HOH C . 
K 3 HOH 110 810  673  HOH HOH C . 
K 3 HOH 111 811  666  HOH HOH C . 
K 3 HOH 112 812  595  HOH HOH C . 
K 3 HOH 113 813  663  HOH HOH C . 
K 3 HOH 114 814  608  HOH HOH C . 
K 3 HOH 115 815  669  HOH HOH C . 
K 3 HOH 116 816  664  HOH HOH C . 
K 3 HOH 117 817  622  HOH HOH C . 
K 3 HOH 118 818  766  HOH HOH C . 
K 3 HOH 119 819  727  HOH HOH C . 
K 3 HOH 120 820  586  HOH HOH C . 
K 3 HOH 121 821  745  HOH HOH C . 
K 3 HOH 122 822  1177 HOH HOH C . 
K 3 HOH 123 823  1276 HOH HOH C . 
K 3 HOH 124 824  1295 HOH HOH C . 
K 3 HOH 125 825  806  HOH HOH C . 
K 3 HOH 126 826  645  HOH HOH C . 
K 3 HOH 127 827  768  HOH HOH C . 
K 3 HOH 128 828  578  HOH HOH C . 
K 3 HOH 129 829  1243 HOH HOH C . 
K 3 HOH 130 830  1470 HOH HOH C . 
K 3 HOH 131 831  1191 HOH HOH C . 
K 3 HOH 132 832  580  HOH HOH C . 
K 3 HOH 133 833  604  HOH HOH C . 
K 3 HOH 134 834  611  HOH HOH C . 
K 3 HOH 135 835  590  HOH HOH C . 
K 3 HOH 136 836  606  HOH HOH C . 
K 3 HOH 137 837  589  HOH HOH C . 
K 3 HOH 138 838  1250 HOH HOH C . 
K 3 HOH 139 839  738  HOH HOH C . 
K 3 HOH 140 840  707  HOH HOH C . 
K 3 HOH 141 841  696  HOH HOH C . 
K 3 HOH 142 842  685  HOH HOH C . 
K 3 HOH 143 843  759  HOH HOH C . 
K 3 HOH 144 844  777  HOH HOH C . 
K 3 HOH 145 845  709  HOH HOH C . 
K 3 HOH 146 846  755  HOH HOH C . 
K 3 HOH 147 847  667  HOH HOH C . 
K 3 HOH 148 848  618  HOH HOH C . 
K 3 HOH 149 849  784  HOH HOH C . 
K 3 HOH 150 850  1362 HOH HOH C . 
K 3 HOH 151 851  792  HOH HOH C . 
K 3 HOH 152 852  638  HOH HOH C . 
K 3 HOH 153 853  623  HOH HOH C . 
K 3 HOH 154 854  756  HOH HOH C . 
K 3 HOH 155 855  571  HOH HOH C . 
K 3 HOH 156 856  670  HOH HOH C . 
K 3 HOH 157 857  1180 HOH HOH C . 
K 3 HOH 158 858  584  HOH HOH C . 
K 3 HOH 159 859  1383 HOH HOH C . 
K 3 HOH 160 860  1317 HOH HOH C . 
K 3 HOH 161 861  621  HOH HOH C . 
K 3 HOH 162 862  698  HOH HOH C . 
K 3 HOH 163 863  774  HOH HOH C . 
K 3 HOH 164 864  747  HOH HOH C . 
K 3 HOH 165 865  835  HOH HOH C . 
K 3 HOH 166 866  813  HOH HOH C . 
K 3 HOH 167 867  679  HOH HOH C . 
K 3 HOH 168 868  786  HOH HOH C . 
K 3 HOH 169 869  594  HOH HOH C . 
K 3 HOH 170 870  1440 HOH HOH C . 
K 3 HOH 171 871  614  HOH HOH C . 
K 3 HOH 172 872  627  HOH HOH C . 
K 3 HOH 173 873  695  HOH HOH C . 
K 3 HOH 174 874  820  HOH HOH C . 
K 3 HOH 175 875  642  HOH HOH C . 
K 3 HOH 176 876  613  HOH HOH C . 
K 3 HOH 177 877  827  HOH HOH C . 
K 3 HOH 178 878  825  HOH HOH C . 
K 3 HOH 179 879  741  HOH HOH C . 
K 3 HOH 180 880  697  HOH HOH C . 
K 3 HOH 181 881  1462 HOH HOH C . 
K 3 HOH 182 882  582  HOH HOH C . 
K 3 HOH 183 883  803  HOH HOH C . 
K 3 HOH 184 884  588  HOH HOH C . 
K 3 HOH 185 885  705  HOH HOH C . 
K 3 HOH 186 886  1316 HOH HOH C . 
K 3 HOH 187 887  579  HOH HOH C . 
K 3 HOH 188 888  1418 HOH HOH C . 
K 3 HOH 189 889  754  HOH HOH C . 
K 3 HOH 190 890  677  HOH HOH C . 
K 3 HOH 191 891  775  HOH HOH C . 
K 3 HOH 192 892  1473 HOH HOH C . 
K 3 HOH 193 893  862  HOH HOH C . 
K 3 HOH 194 894  781  HOH HOH C . 
K 3 HOH 195 895  1315 HOH HOH C . 
K 3 HOH 196 896  661  HOH HOH C . 
K 3 HOH 197 897  655  HOH HOH C . 
K 3 HOH 198 898  597  HOH HOH C . 
K 3 HOH 199 899  684  HOH HOH C . 
K 3 HOH 200 900  680  HOH HOH C . 
K 3 HOH 201 901  1387 HOH HOH C . 
K 3 HOH 202 902  805  HOH HOH C . 
K 3 HOH 203 903  1480 HOH HOH C . 
K 3 HOH 204 904  771  HOH HOH C . 
K 3 HOH 205 905  742  HOH HOH C . 
K 3 HOH 206 906  966  HOH HOH C . 
K 3 HOH 207 907  676  HOH HOH C . 
K 3 HOH 208 908  733  HOH HOH C . 
K 3 HOH 209 909  675  HOH HOH C . 
K 3 HOH 210 910  811  HOH HOH C . 
K 3 HOH 211 911  772  HOH HOH C . 
K 3 HOH 212 912  1415 HOH HOH C . 
K 3 HOH 213 913  1352 HOH HOH C . 
K 3 HOH 214 914  1224 HOH HOH C . 
K 3 HOH 215 915  724  HOH HOH C . 
K 3 HOH 216 916  1437 HOH HOH C . 
K 3 HOH 217 917  605  HOH HOH C . 
K 3 HOH 218 918  686  HOH HOH C . 
K 3 HOH 219 919  1307 HOH HOH C . 
K 3 HOH 220 920  809  HOH HOH C . 
K 3 HOH 221 921  796  HOH HOH C . 
K 3 HOH 222 922  1252 HOH HOH C . 
K 3 HOH 223 923  833  HOH HOH C . 
K 3 HOH 224 924  1207 HOH HOH C . 
K 3 HOH 225 925  682  HOH HOH C . 
K 3 HOH 226 926  631  HOH HOH C . 
K 3 HOH 227 927  800  HOH HOH C . 
K 3 HOH 228 928  832  HOH HOH C . 
K 3 HOH 229 929  783  HOH HOH C . 
K 3 HOH 230 930  810  HOH HOH C . 
K 3 HOH 231 931  646  HOH HOH C . 
K 3 HOH 232 932  1281 HOH HOH C . 
K 3 HOH 233 933  1165 HOH HOH C . 
K 3 HOH 234 934  776  HOH HOH C . 
K 3 HOH 235 935  782  HOH HOH C . 
K 3 HOH 236 936  1280 HOH HOH C . 
K 3 HOH 237 937  1175 HOH HOH C . 
K 3 HOH 238 938  658  HOH HOH C . 
K 3 HOH 239 939  1442 HOH HOH C . 
K 3 HOH 240 940  690  HOH HOH C . 
K 3 HOH 241 941  1479 HOH HOH C . 
K 3 HOH 242 942  1443 HOH HOH C . 
K 3 HOH 243 943  721  HOH HOH C . 
K 3 HOH 244 944  1305 HOH HOH C . 
K 3 HOH 245 945  765  HOH HOH C . 
K 3 HOH 246 946  1414 HOH HOH C . 
K 3 HOH 247 947  1395 HOH HOH C . 
K 3 HOH 248 948  834  HOH HOH C . 
K 3 HOH 249 949  801  HOH HOH C . 
K 3 HOH 250 950  1294 HOH HOH C . 
K 3 HOH 251 951  753  HOH HOH C . 
K 3 HOH 252 952  1157 HOH HOH C . 
K 3 HOH 253 953  1331 HOH HOH C . 
K 3 HOH 254 954  717  HOH HOH C . 
K 3 HOH 255 955  824  HOH HOH C . 
K 3 HOH 256 956  815  HOH HOH C . 
K 3 HOH 257 957  718  HOH HOH C . 
K 3 HOH 258 958  713  HOH HOH C . 
K 3 HOH 259 959  787  HOH HOH C . 
K 3 HOH 260 960  1215 HOH HOH C . 
K 3 HOH 261 961  1424 HOH HOH C . 
K 3 HOH 262 962  659  HOH HOH C . 
K 3 HOH 263 963  1160 HOH HOH C . 
K 3 HOH 264 964  1410 HOH HOH C . 
K 3 HOH 265 965  836  HOH HOH C . 
K 3 HOH 266 966  794  HOH HOH C . 
K 3 HOH 267 967  1232 HOH HOH C . 
K 3 HOH 268 968  660  HOH HOH C . 
K 3 HOH 269 969  1199 HOH HOH C . 
K 3 HOH 270 970  693  HOH HOH C . 
K 3 HOH 271 971  761  HOH HOH C . 
K 3 HOH 272 972  1273 HOH HOH C . 
K 3 HOH 273 973  1208 HOH HOH C . 
K 3 HOH 274 974  702  HOH HOH C . 
K 3 HOH 275 975  729  HOH HOH C . 
K 3 HOH 276 976  752  HOH HOH C . 
K 3 HOH 277 977  1240 HOH HOH C . 
K 3 HOH 278 978  722  HOH HOH C . 
K 3 HOH 279 979  1495 HOH HOH C . 
K 3 HOH 280 980  1190 HOH HOH C . 
K 3 HOH 281 981  1296 HOH HOH C . 
K 3 HOH 282 982  743  HOH HOH C . 
K 3 HOH 283 983  830  HOH HOH C . 
K 3 HOH 284 984  637  HOH HOH C . 
K 3 HOH 285 985  1188 HOH HOH C . 
K 3 HOH 286 986  739  HOH HOH C . 
K 3 HOH 287 987  710  HOH HOH C . 
K 3 HOH 288 988  726  HOH HOH C . 
K 3 HOH 289 989  791  HOH HOH C . 
K 3 HOH 290 990  1409 HOH HOH C . 
K 3 HOH 291 991  819  HOH HOH C . 
K 3 HOH 292 992  650  HOH HOH C . 
K 3 HOH 293 993  789  HOH HOH C . 
K 3 HOH 294 994  788  HOH HOH C . 
K 3 HOH 295 995  799  HOH HOH C . 
K 3 HOH 296 996  723  HOH HOH C . 
K 3 HOH 297 997  760  HOH HOH C . 
K 3 HOH 298 998  807  HOH HOH C . 
K 3 HOH 299 999  1168 HOH HOH C . 
K 3 HOH 300 1000 793  HOH HOH C . 
K 3 HOH 301 1001 831  HOH HOH C . 
K 3 HOH 302 1002 1313 HOH HOH C . 
K 3 HOH 303 1003 657  HOH HOH C . 
K 3 HOH 304 1004 1205 HOH HOH C . 
K 3 HOH 305 1005 1163 HOH HOH C . 
K 3 HOH 306 1006 1285 HOH HOH C . 
K 3 HOH 307 1007 1293 HOH HOH C . 
K 3 HOH 308 1008 634  HOH HOH C . 
K 3 HOH 309 1009 1386 HOH HOH C . 
K 3 HOH 310 1010 688  HOH HOH C . 
K 3 HOH 311 1011 1004 HOH HOH C . 
K 3 HOH 312 1012 828  HOH HOH C . 
K 3 HOH 313 1013 1267 HOH HOH C . 
K 3 HOH 314 1014 769  HOH HOH C . 
K 3 HOH 315 1015 687  HOH HOH C . 
K 3 HOH 316 1016 795  HOH HOH C . 
K 3 HOH 317 1017 1326 HOH HOH C . 
K 3 HOH 318 1018 822  HOH HOH C . 
K 3 HOH 319 1019 817  HOH HOH C . 
K 3 HOH 320 1020 701  HOH HOH C . 
K 3 HOH 321 1021 1302 HOH HOH C . 
K 3 HOH 322 1022 1289 HOH HOH C . 
K 3 HOH 323 1023 1164 HOH HOH C . 
K 3 HOH 324 1024 681  HOH HOH C . 
K 3 HOH 325 1025 700  HOH HOH C . 
K 3 HOH 326 1026 647  HOH HOH C . 
K 3 HOH 327 1027 779  HOH HOH C . 
K 3 HOH 328 1028 672  HOH HOH C . 
K 3 HOH 329 1029 691  HOH HOH C . 
K 3 HOH 330 1030 1476 HOH HOH C . 
K 3 HOH 331 1031 1425 HOH HOH C . 
K 3 HOH 332 1032 1030 HOH HOH C . 
K 3 HOH 333 1033 1214 HOH HOH C . 
K 3 HOH 334 1034 1372 HOH HOH C . 
K 3 HOH 335 1035 343  HOH HOH C . 
K 3 HOH 336 1036 737  HOH HOH C . 
K 3 HOH 337 1037 1334 HOH HOH C . 
K 3 HOH 338 1038 798  HOH HOH C . 
K 3 HOH 339 1039 712  HOH HOH C . 
K 3 HOH 340 1040 1357 HOH HOH C . 
K 3 HOH 341 1041 757  HOH HOH C . 
K 3 HOH 342 1042 758  HOH HOH C . 
K 3 HOH 343 1043 1376 HOH HOH C . 
K 3 HOH 344 1044 1374 HOH HOH C . 
K 3 HOH 345 1045 683  HOH HOH C . 
K 3 HOH 346 1046 785  HOH HOH C . 
K 3 HOH 347 1047 826  HOH HOH C . 
K 3 HOH 348 1048 735  HOH HOH C . 
L 3 HOH 1   701  884  HOH HOH D . 
L 3 HOH 2   702  1028 HOH HOH D . 
L 3 HOH 3   703  1405 HOH HOH D . 
L 3 HOH 4   704  971  HOH HOH D . 
L 3 HOH 5   705  1045 HOH HOH D . 
L 3 HOH 6   706  855  HOH HOH D . 
L 3 HOH 7   707  197  HOH HOH D . 
L 3 HOH 8   708  885  HOH HOH D . 
L 3 HOH 9   709  1506 HOH HOH D . 
L 3 HOH 10  710  994  HOH HOH D . 
L 3 HOH 11  711  1100 HOH HOH D . 
L 3 HOH 12  712  957  HOH HOH D . 
L 3 HOH 13  713  844  HOH HOH D . 
L 3 HOH 14  714  1300 HOH HOH D . 
L 3 HOH 15  715  895  HOH HOH D . 
L 3 HOH 16  716  977  HOH HOH D . 
L 3 HOH 17  717  849  HOH HOH D . 
L 3 HOH 18  718  915  HOH HOH D . 
L 3 HOH 19  719  1131 HOH HOH D . 
L 3 HOH 20  720  1449 HOH HOH D . 
L 3 HOH 21  721  802  HOH HOH D . 
L 3 HOH 22  722  1340 HOH HOH D . 
L 3 HOH 23  723  975  HOH HOH D . 
L 3 HOH 24  724  914  HOH HOH D . 
L 3 HOH 25  725  1489 HOH HOH D . 
L 3 HOH 26  726  624  HOH HOH D . 
L 3 HOH 27  727  922  HOH HOH D . 
L 3 HOH 28  728  1507 HOH HOH D . 
L 3 HOH 29  729  911  HOH HOH D . 
L 3 HOH 30  730  949  HOH HOH D . 
L 3 HOH 31  731  1038 HOH HOH D . 
L 3 HOH 32  732  1490 HOH HOH D . 
L 3 HOH 33  733  859  HOH HOH D . 
L 3 HOH 34  734  923  HOH HOH D . 
L 3 HOH 35  735  1369 HOH HOH D . 
L 3 HOH 36  736  962  HOH HOH D . 
L 3 HOH 37  737  930  HOH HOH D . 
L 3 HOH 38  738  933  HOH HOH D . 
L 3 HOH 39  739  874  HOH HOH D . 
L 3 HOH 40  740  980  HOH HOH D . 
L 3 HOH 41  741  893  HOH HOH D . 
L 3 HOH 42  742  992  HOH HOH D . 
L 3 HOH 43  743  1237 HOH HOH D . 
L 3 HOH 44  744  903  HOH HOH D . 
L 3 HOH 45  745  887  HOH HOH D . 
L 3 HOH 46  746  954  HOH HOH D . 
L 3 HOH 47  747  882  HOH HOH D . 
L 3 HOH 48  748  972  HOH HOH D . 
L 3 HOH 49  749  870  HOH HOH D . 
L 3 HOH 50  750  843  HOH HOH D . 
L 3 HOH 51  751  899  HOH HOH D . 
L 3 HOH 52  752  965  HOH HOH D . 
L 3 HOH 53  753  925  HOH HOH D . 
L 3 HOH 54  754  865  HOH HOH D . 
L 3 HOH 55  755  924  HOH HOH D . 
L 3 HOH 56  756  875  HOH HOH D . 
L 3 HOH 57  757  852  HOH HOH D . 
L 3 HOH 58  758  883  HOH HOH D . 
L 3 HOH 59  759  1445 HOH HOH D . 
L 3 HOH 60  760  872  HOH HOH D . 
L 3 HOH 61  761  944  HOH HOH D . 
L 3 HOH 62  762  896  HOH HOH D . 
L 3 HOH 63  763  888  HOH HOH D . 
L 3 HOH 64  764  1023 HOH HOH D . 
L 3 HOH 65  765  932  HOH HOH D . 
L 3 HOH 66  766  1116 HOH HOH D . 
L 3 HOH 67  767  900  HOH HOH D . 
L 3 HOH 68  768  639  HOH HOH D . 
L 3 HOH 69  769  938  HOH HOH D . 
L 3 HOH 70  770  1492 HOH HOH D . 
L 3 HOH 71  771  868  HOH HOH D . 
L 3 HOH 72  772  1009 HOH HOH D . 
L 3 HOH 73  773  1497 HOH HOH D . 
L 3 HOH 74  774  596  HOH HOH D . 
L 3 HOH 75  775  940  HOH HOH D . 
L 3 HOH 76  776  897  HOH HOH D . 
L 3 HOH 77  777  984  HOH HOH D . 
L 3 HOH 78  778  919  HOH HOH D . 
L 3 HOH 79  779  856  HOH HOH D . 
L 3 HOH 80  780  967  HOH HOH D . 
L 3 HOH 81  781  961  HOH HOH D . 
L 3 HOH 82  782  626  HOH HOH D . 
L 3 HOH 83  783  1503 HOH HOH D . 
L 3 HOH 84  784  577  HOH HOH D . 
L 3 HOH 85  785  1026 HOH HOH D . 
L 3 HOH 86  786  950  HOH HOH D . 
L 3 HOH 87  787  902  HOH HOH D . 
L 3 HOH 88  788  152  HOH HOH D . 
L 3 HOH 89  789  927  HOH HOH D . 
L 3 HOH 90  790  1015 HOH HOH D . 
L 3 HOH 91  791  1057 HOH HOH D . 
L 3 HOH 92  792  1320 HOH HOH D . 
L 3 HOH 93  793  937  HOH HOH D . 
L 3 HOH 94  794  857  HOH HOH D . 
L 3 HOH 95  795  1148 HOH HOH D . 
L 3 HOH 96  796  1109 HOH HOH D . 
L 3 HOH 97  797  958  HOH HOH D . 
L 3 HOH 98  798  904  HOH HOH D . 
L 3 HOH 99  799  841  HOH HOH D . 
L 3 HOH 100 800  1090 HOH HOH D . 
L 3 HOH 101 801  1472 HOH HOH D . 
L 3 HOH 102 802  649  HOH HOH D . 
L 3 HOH 103 803  869  HOH HOH D . 
L 3 HOH 104 804  1037 HOH HOH D . 
L 3 HOH 105 805  860  HOH HOH D . 
L 3 HOH 106 806  1025 HOH HOH D . 
L 3 HOH 107 807  928  HOH HOH D . 
L 3 HOH 108 808  988  HOH HOH D . 
L 3 HOH 109 809  1082 HOH HOH D . 
L 3 HOH 110 810  1353 HOH HOH D . 
L 3 HOH 111 811  1071 HOH HOH D . 
L 3 HOH 112 812  1031 HOH HOH D . 
L 3 HOH 113 813  878  HOH HOH D . 
L 3 HOH 114 814  866  HOH HOH D . 
L 3 HOH 115 815  886  HOH HOH D . 
L 3 HOH 116 816  1013 HOH HOH D . 
L 3 HOH 117 817  845  HOH HOH D . 
L 3 HOH 118 818  877  HOH HOH D . 
L 3 HOH 119 819  1084 HOH HOH D . 
L 3 HOH 120 820  951  HOH HOH D . 
L 3 HOH 121 821  871  HOH HOH D . 
L 3 HOH 122 822  851  HOH HOH D . 
L 3 HOH 123 823  867  HOH HOH D . 
L 3 HOH 124 824  969  HOH HOH D . 
L 3 HOH 125 825  1018 HOH HOH D . 
L 3 HOH 126 826  1322 HOH HOH D . 
L 3 HOH 127 827  858  HOH HOH D . 
L 3 HOH 128 828  934  HOH HOH D . 
L 3 HOH 129 829  838  HOH HOH D . 
L 3 HOH 130 830  839  HOH HOH D . 
L 3 HOH 131 831  847  HOH HOH D . 
L 3 HOH 132 832  1263 HOH HOH D . 
L 3 HOH 133 833  1460 HOH HOH D . 
L 3 HOH 134 834  976  HOH HOH D . 
L 3 HOH 135 835  936  HOH HOH D . 
L 3 HOH 136 836  191  HOH HOH D . 
L 3 HOH 137 837  864  HOH HOH D . 
L 3 HOH 138 838  846  HOH HOH D . 
L 3 HOH 139 839  947  HOH HOH D . 
L 3 HOH 140 840  1270 HOH HOH D . 
L 3 HOH 141 841  850  HOH HOH D . 
L 3 HOH 142 842  1080 HOH HOH D . 
L 3 HOH 143 843  1075 HOH HOH D . 
L 3 HOH 144 844  1102 HOH HOH D . 
L 3 HOH 145 845  1076 HOH HOH D . 
L 3 HOH 146 846  1203 HOH HOH D . 
L 3 HOH 147 847  879  HOH HOH D . 
L 3 HOH 148 848  1391 HOH HOH D . 
L 3 HOH 149 849  986  HOH HOH D . 
L 3 HOH 150 850  1055 HOH HOH D . 
L 3 HOH 151 851  861  HOH HOH D . 
L 3 HOH 152 852  731  HOH HOH D . 
L 3 HOH 153 853  1001 HOH HOH D . 
L 3 HOH 154 854  1337 HOH HOH D . 
L 3 HOH 155 855  987  HOH HOH D . 
L 3 HOH 156 856  1235 HOH HOH D . 
L 3 HOH 157 857  873  HOH HOH D . 
L 3 HOH 158 858  1091 HOH HOH D . 
L 3 HOH 159 859  876  HOH HOH D . 
L 3 HOH 160 860  989  HOH HOH D . 
L 3 HOH 161 861  963  HOH HOH D . 
L 3 HOH 162 862  881  HOH HOH D . 
L 3 HOH 163 863  164  HOH HOH D . 
L 3 HOH 164 864  1039 HOH HOH D . 
L 3 HOH 165 865  974  HOH HOH D . 
L 3 HOH 166 866  956  HOH HOH D . 
L 3 HOH 167 867  921  HOH HOH D . 
L 3 HOH 168 868  1066 HOH HOH D . 
L 3 HOH 169 869  854  HOH HOH D . 
L 3 HOH 170 870  1284 HOH HOH D . 
L 3 HOH 171 871  842  HOH HOH D . 
L 3 HOH 172 872  1067 HOH HOH D . 
L 3 HOH 173 873  1439 HOH HOH D . 
L 3 HOH 174 874  1166 HOH HOH D . 
L 3 HOH 175 875  1192 HOH HOH D . 
L 3 HOH 176 876  952  HOH HOH D . 
L 3 HOH 177 877  1115 HOH HOH D . 
L 3 HOH 178 878  941  HOH HOH D . 
L 3 HOH 179 879  917  HOH HOH D . 
L 3 HOH 180 880  1124 HOH HOH D . 
L 3 HOH 181 881  982  HOH HOH D . 
L 3 HOH 182 882  1170 HOH HOH D . 
L 3 HOH 183 883  135  HOH HOH D . 
L 3 HOH 184 884  1050 HOH HOH D . 
L 3 HOH 185 885  910  HOH HOH D . 
L 3 HOH 186 886  905  HOH HOH D . 
L 3 HOH 187 887  985  HOH HOH D . 
L 3 HOH 188 888  1027 HOH HOH D . 
L 3 HOH 189 889  848  HOH HOH D . 
L 3 HOH 190 890  1095 HOH HOH D . 
L 3 HOH 191 891  891  HOH HOH D . 
L 3 HOH 192 892  990  HOH HOH D . 
L 3 HOH 193 893  931  HOH HOH D . 
L 3 HOH 194 894  892  HOH HOH D . 
L 3 HOH 195 895  1471 HOH HOH D . 
L 3 HOH 196 896  1012 HOH HOH D . 
L 3 HOH 197 897  1088 HOH HOH D . 
L 3 HOH 198 898  1049 HOH HOH D . 
L 3 HOH 199 899  863  HOH HOH D . 
L 3 HOH 200 900  1234 HOH HOH D . 
L 3 HOH 201 901  973  HOH HOH D . 
L 3 HOH 202 902  909  HOH HOH D . 
L 3 HOH 203 903  1002 HOH HOH D . 
L 3 HOH 204 904  1048 HOH HOH D . 
L 3 HOH 205 905  1145 HOH HOH D . 
L 3 HOH 206 906  517  HOH HOH D . 
L 3 HOH 207 907  1133 HOH HOH D . 
L 3 HOH 208 908  1123 HOH HOH D . 
L 3 HOH 209 909  991  HOH HOH D . 
L 3 HOH 210 910  1064 HOH HOH D . 
L 3 HOH 211 911  1239 HOH HOH D . 
L 3 HOH 212 912  920  HOH HOH D . 
L 3 HOH 213 913  1079 HOH HOH D . 
L 3 HOH 214 914  945  HOH HOH D . 
L 3 HOH 215 915  1186 HOH HOH D . 
L 3 HOH 216 916  1198 HOH HOH D . 
L 3 HOH 217 917  1058 HOH HOH D . 
L 3 HOH 218 918  1029 HOH HOH D . 
L 3 HOH 219 919  1054 HOH HOH D . 
L 3 HOH 220 920  1020 HOH HOH D . 
L 3 HOH 221 921  1005 HOH HOH D . 
L 3 HOH 222 922  1072 HOH HOH D . 
L 3 HOH 223 923  734  HOH HOH D . 
L 3 HOH 224 924  1040 HOH HOH D . 
L 3 HOH 225 925  1022 HOH HOH D . 
L 3 HOH 226 926  981  HOH HOH D . 
L 3 HOH 227 927  1119 HOH HOH D . 
L 3 HOH 228 928  942  HOH HOH D . 
L 3 HOH 229 929  1059 HOH HOH D . 
L 3 HOH 230 930  1349 HOH HOH D . 
L 3 HOH 231 931  1081 HOH HOH D . 
L 3 HOH 232 932  1032 HOH HOH D . 
L 3 HOH 233 933  1438 HOH HOH D . 
L 3 HOH 234 934  901  HOH HOH D . 
L 3 HOH 235 935  1021 HOH HOH D . 
L 3 HOH 236 936  978  HOH HOH D . 
L 3 HOH 237 937  1010 HOH HOH D . 
L 3 HOH 238 938  999  HOH HOH D . 
L 3 HOH 239 939  853  HOH HOH D . 
L 3 HOH 240 940  1077 HOH HOH D . 
L 3 HOH 241 941  131  HOH HOH D . 
L 3 HOH 242 942  1087 HOH HOH D . 
L 3 HOH 243 943  1003 HOH HOH D . 
L 3 HOH 244 944  1118 HOH HOH D . 
L 3 HOH 245 945  1044 HOH HOH D . 
L 3 HOH 246 946  1074 HOH HOH D . 
L 3 HOH 247 947  983  HOH HOH D . 
L 3 HOH 248 948  908  HOH HOH D . 
L 3 HOH 249 949  1143 HOH HOH D . 
L 3 HOH 250 950  906  HOH HOH D . 
L 3 HOH 251 951  1117 HOH HOH D . 
L 3 HOH 252 952  979  HOH HOH D . 
L 3 HOH 253 953  943  HOH HOH D . 
L 3 HOH 254 954  1238 HOH HOH D . 
L 3 HOH 255 955  907  HOH HOH D . 
L 3 HOH 256 956  1053 HOH HOH D . 
L 3 HOH 257 957  1137 HOH HOH D . 
L 3 HOH 258 958  1083 HOH HOH D . 
L 3 HOH 259 959  946  HOH HOH D . 
L 3 HOH 260 960  1101 HOH HOH D . 
L 3 HOH 261 961  1114 HOH HOH D . 
L 3 HOH 262 962  740  HOH HOH D . 
L 3 HOH 263 963  1212 HOH HOH D . 
L 3 HOH 264 964  1056 HOH HOH D . 
L 3 HOH 265 965  968  HOH HOH D . 
L 3 HOH 266 966  1321 HOH HOH D . 
L 3 HOH 267 967  1200 HOH HOH D . 
L 3 HOH 268 968  1185 HOH HOH D . 
L 3 HOH 269 969  1034 HOH HOH D . 
L 3 HOH 270 970  1229 HOH HOH D . 
L 3 HOH 271 971  1167 HOH HOH D . 
L 3 HOH 272 972  1332 HOH HOH D . 
L 3 HOH 273 973  1328 HOH HOH D . 
L 3 HOH 274 974  79   HOH HOH D . 
L 3 HOH 275 975  1446 HOH HOH D . 
L 3 HOH 276 976  1129 HOH HOH D . 
L 3 HOH 277 977  996  HOH HOH D . 
L 3 HOH 278 978  1112 HOH HOH D . 
L 3 HOH 279 979  964  HOH HOH D . 
L 3 HOH 280 980  1504 HOH HOH D . 
L 3 HOH 281 981  1162 HOH HOH D . 
L 3 HOH 282 982  1345 HOH HOH D . 
L 3 HOH 283 983  1093 HOH HOH D . 
L 3 HOH 284 984  1125 HOH HOH D . 
L 3 HOH 285 985  1120 HOH HOH D . 
L 3 HOH 286 986  1047 HOH HOH D . 
L 3 HOH 287 987  1404 HOH HOH D . 
L 3 HOH 288 988  918  HOH HOH D . 
L 3 HOH 289 989  948  HOH HOH D . 
L 3 HOH 290 990  1006 HOH HOH D . 
L 3 HOH 291 991  916  HOH HOH D . 
L 3 HOH 292 992  1411 HOH HOH D . 
L 3 HOH 293 993  998  HOH HOH D . 
L 3 HOH 294 994  1484 HOH HOH D . 
L 3 HOH 295 995  1108 HOH HOH D . 
L 3 HOH 296 996  1309 HOH HOH D . 
L 3 HOH 297 997  926  HOH HOH D . 
L 3 HOH 298 998  1113 HOH HOH D . 
L 3 HOH 299 999  1051 HOH HOH D . 
L 3 HOH 300 1000 1110 HOH HOH D . 
L 3 HOH 301 1001 1311 HOH HOH D . 
L 3 HOH 302 1002 1107 HOH HOH D . 
L 3 HOH 303 1003 1063 HOH HOH D . 
L 3 HOH 304 1004 1035 HOH HOH D . 
L 3 HOH 305 1005 762  HOH HOH D . 
L 3 HOH 306 1006 1393 HOH HOH D . 
L 3 HOH 307 1007 1104 HOH HOH D . 
L 3 HOH 308 1008 816  HOH HOH D . 
L 3 HOH 309 1009 1447 HOH HOH D . 
L 3 HOH 310 1010 1189 HOH HOH D . 
L 3 HOH 311 1011 1427 HOH HOH D . 
L 3 HOH 312 1012 1042 HOH HOH D . 
L 3 HOH 313 1013 1008 HOH HOH D . 
L 3 HOH 314 1014 1182 HOH HOH D . 
L 3 HOH 315 1015 1017 HOH HOH D . 
L 3 HOH 316 1016 1448 HOH HOH D . 
L 3 HOH 317 1017 1249 HOH HOH D . 
L 3 HOH 318 1018 1412 HOH HOH D . 
L 3 HOH 319 1019 1245 HOH HOH D . 
L 3 HOH 320 1020 1098 HOH HOH D . 
L 3 HOH 321 1021 1375 HOH HOH D . 
L 3 HOH 322 1022 1069 HOH HOH D . 
L 3 HOH 323 1023 1019 HOH HOH D . 
L 3 HOH 324 1024 1126 HOH HOH D . 
L 3 HOH 325 1025 1060 HOH HOH D . 
L 3 HOH 326 1026 1128 HOH HOH D . 
L 3 HOH 327 1027 1483 HOH HOH D . 
L 3 HOH 328 1028 898  HOH HOH D . 
L 3 HOH 329 1029 1105 HOH HOH D . 
L 3 HOH 330 1030 997  HOH HOH D . 
L 3 HOH 331 1031 970  HOH HOH D . 
L 3 HOH 332 1032 894  HOH HOH D . 
L 3 HOH 333 1033 1465 HOH HOH D . 
L 3 HOH 334 1034 890  HOH HOH D . 
L 3 HOH 335 1035 1046 HOH HOH D . 
L 3 HOH 336 1036 1000 HOH HOH D . 
L 3 HOH 337 1037 1279 HOH HOH D . 
L 3 HOH 338 1038 1493 HOH HOH D . 
L 3 HOH 339 1039 1061 HOH HOH D . 
L 3 HOH 340 1040 1306 HOH HOH D . 
L 3 HOH 341 1041 1401 HOH HOH D . 
L 3 HOH 342 1042 1127 HOH HOH D . 
L 3 HOH 343 1043 1130 HOH HOH D . 
L 3 HOH 344 1044 939  HOH HOH D . 
L 3 HOH 345 1045 1259 HOH HOH D . 
L 3 HOH 346 1046 1070 HOH HOH D . 
L 3 HOH 347 1047 1099 HOH HOH D . 
L 3 HOH 348 1048 814  HOH HOH D . 
L 3 HOH 349 1049 993  HOH HOH D . 
L 3 HOH 350 1050 1011 HOH HOH D . 
L 3 HOH 351 1051 1323 HOH HOH D . 
L 3 HOH 352 1052 1097 HOH HOH D . 
L 3 HOH 353 1053 1134 HOH HOH D . 
L 3 HOH 354 1054 1121 HOH HOH D . 
L 3 HOH 355 1055 929  HOH HOH D . 
L 3 HOH 356 1056 995  HOH HOH D . 
L 3 HOH 357 1057 1365 HOH HOH D . 
L 3 HOH 358 1058 1085 HOH HOH D . 
L 3 HOH 359 1059 1428 HOH HOH D . 
L 3 HOH 360 1060 955  HOH HOH D . 
L 3 HOH 361 1061 1094 HOH HOH D . 
L 3 HOH 362 1062 912  HOH HOH D . 
L 3 HOH 363 1063 1007 HOH HOH D . 
L 3 HOH 364 1064 953  HOH HOH D . 
L 3 HOH 365 1065 1103 HOH HOH D . 
L 3 HOH 366 1066 1287 HOH HOH D . 
L 3 HOH 367 1067 1256 HOH HOH D . 
L 3 HOH 368 1068 1380 HOH HOH D . 
L 3 HOH 369 1069 960  HOH HOH D . 
L 3 HOH 370 1070 653  HOH HOH D . 
L 3 HOH 371 1071 1096 HOH HOH D . 
L 3 HOH 372 1072 1033 HOH HOH D . 
L 3 HOH 373 1073 1122 HOH HOH D . 
L 3 HOH 374 1074 1254 HOH HOH D . 
L 3 HOH 375 1075 1062 HOH HOH D . 
L 3 HOH 376 1076 1016 HOH HOH D . 
L 3 HOH 377 1077 1154 HOH HOH D . 
L 3 HOH 378 1078 1379 HOH HOH D . 
L 3 HOH 379 1079 1073 HOH HOH D . 
L 3 HOH 380 1080 1111 HOH HOH D . 
L 3 HOH 381 1081 1194 HOH HOH D . 
L 3 HOH 382 1082 913  HOH HOH D . 
L 3 HOH 383 1083 1242 HOH HOH D . 
L 3 HOH 384 1084 1043 HOH HOH D . 
L 3 HOH 385 1085 1036 HOH HOH D . 
L 3 HOH 386 1086 1089 HOH HOH D . 
L 3 HOH 387 1087 1218 HOH HOH D . 
L 3 HOH 388 1088 1068 HOH HOH D . 
L 3 HOH 389 1089 1086 HOH HOH D . 
L 3 HOH 390 1090 959  HOH HOH D . 
L 3 HOH 391 1091 471  HOH HOH D . 
L 3 HOH 392 1092 880  HOH HOH D . 
L 3 HOH 393 1093 1474 HOH HOH D . 
L 3 HOH 394 1094 1342 HOH HOH D . 
L 3 HOH 395 1095 1136 HOH HOH D . 
L 3 HOH 396 1096 1041 HOH HOH D . 
L 3 HOH 397 1097 1373 HOH HOH D . 
L 3 HOH 398 1098 1065 HOH HOH D . 
L 3 HOH 399 1099 935  HOH HOH D . 
L 3 HOH 400 1100 1301 HOH HOH D . 
L 3 HOH 401 1101 1106 HOH HOH D . 
L 3 HOH 402 1102 1140 HOH HOH D . 
L 3 HOH 403 1103 1052 HOH HOH D . 
L 3 HOH 404 1104 1078 HOH HOH D . 
L 3 HOH 405 1105 1339 HOH HOH D . 
L 3 HOH 406 1106 1333 HOH HOH D . 
L 3 HOH 407 1107 1132 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 D GLU 461 ? CG  ? D GLU 468 CG  
2 1 Y 1 D GLU 461 ? CD  ? D GLU 468 CD  
3 1 Y 1 D GLU 461 ? OE1 ? D GLU 468 OE1 
4 1 Y 1 D GLU 461 ? OE2 ? D GLU 468 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC    ? ? ? 5.8.0267 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? STARANISO ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS       ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER    ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R2P 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     73.260 
_cell.length_a_esd                 ? 
_cell.length_b                     196.760 
_cell.length_b_esd                 ? 
_cell.length_c                     208.053 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R2P 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R2P 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.29 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          62.56 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '50% w/v PEG200, 0.2M MgCl2 and 0.1M Sodium Cacodylate buffer pH 6.5' 
_exptl_crystal_grow.pdbx_pH_range   6.5-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-09-17 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976246 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'MAX IV BEAMLINE BioMAX' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976246 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BioMAX 
_diffrn_source.pdbx_synchrotron_site       'MAX IV' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8R2P 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.217 
_reflns.d_resolution_low                               48.91 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     61481 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           41.1 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.182 
_reflns.pdbx_Rpim_I_all                                0.070 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.167 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.217 
_reflns_shell.d_res_low                                     2.425 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.68 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3073 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               5.12 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.156 
_reflns_shell.pdbx_Rpim_I_all                               0.490 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.665 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          8.8 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.041 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.19 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            0.84 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -0.64 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               32.657 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.959 
_refine.correlation_coeff_Fo_to_Fc_free          0.936 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R2P 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.22 
_refine.ls_d_res_low                             48.91 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     58551 
_refine.ls_number_reflns_R_free                  2928 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    41.07 
_refine.ls_percent_reflns_R_free                 4.8 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.18846 
_refine.ls_R_factor_R_free                       0.23039 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18628 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  0.368 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             7.127 
_refine.overall_SU_ML                            0.171 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.22 
_refine_hist.d_res_low                        48.91 
_refine_hist.number_atoms_solvent             1507 
_refine_hist.number_atoms_total               15886 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        14315 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         64 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.013  15059 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.015  14576 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.464  1.640  20441 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 1.243  1.574  33573 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.251  5.000  1966  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 35.532 22.970 734   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 16.749 15.000 2588  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? 19.156 15.000 86    ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.060  0.200  1964  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020  17470 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  3398  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 2.699  3.303  7750  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 2.695  3.303  7749  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.266  4.940  9754  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.266  4.941  9755  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 3.184  3.656  7309  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.184  3.657  7306  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 5.235  5.351  10688 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.636  63.215 66868 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 9.388  63.279 65109 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.05 ? 0.05 1  'interatomic distance' ? A 14920 ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.05 ? 0.05 2  'interatomic distance' ? B 14920 ? ? 1 
'X-RAY DIFFRACTION' 1 ? ? 0.05 ? 0.05 3  'interatomic distance' ? A 15000 ? ? 2 
'X-RAY DIFFRACTION' 2 ? ? 0.05 ? 0.05 4  'interatomic distance' ? C 15000 ? ? 2 
'X-RAY DIFFRACTION' 1 ? ? 0.06 ? 0.05 5  'interatomic distance' ? A 14940 ? ? 3 
'X-RAY DIFFRACTION' 2 ? ? 0.06 ? 0.05 6  'interatomic distance' ? D 14940 ? ? 3 
'X-RAY DIFFRACTION' 1 ? ? 0.06 ? 0.05 7  'interatomic distance' ? B 15038 ? ? 4 
'X-RAY DIFFRACTION' 2 ? ? 0.06 ? 0.05 8  'interatomic distance' ? C 15038 ? ? 4 
'X-RAY DIFFRACTION' 1 ? ? 0.06 ? 0.05 9  'interatomic distance' ? B 15229 ? ? 5 
'X-RAY DIFFRACTION' 2 ? ? 0.06 ? 0.05 10 'interatomic distance' ? D 15229 ? ? 5 
'X-RAY DIFFRACTION' 1 ? ? 0.07 ? 0.05 11 'interatomic distance' ? C 15185 ? ? 6 
'X-RAY DIFFRACTION' 2 ? ? 0.07 ? 0.05 12 'interatomic distance' ? D 15185 ? ? 6 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.22 
_refine_ls_shell.d_res_low                        2.275 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             5 
_refine_ls_shell.number_reflns_R_work             210 
_refine_ls_shell.percent_reflns_obs               1.96 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.358 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.178 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.details 
_struct_ncs_dom.pdbx_ens_id 
1 ? 1 
2 ? 2 
3 ? 3 
4 ? 4 
5 ? 5 
6 ? 6 
# 
loop_
_struct_ncs_ens.id 
_struct_ncs_ens.details 
1 ? 
2 ? 
3 ? 
4 ? 
5 ? 
6 ? 
# 
_struct.entry_id                     8R2P 
_struct.title                        
'YZwIdeal x16 a scaffold for cryo-EM of small proteins of interest crystallizing in space group 19 (P 21 21 21)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R2P 
_struct_keywords.text            'Scaffold Fusion protein, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP PAT_ECOLI P42588 ? 1 
;SASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFID
CLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQS
PRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGV
ILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNP
FLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFAS
EMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVE
;
7   
2 UNP SPA_STAAU P38507 ? 1 KEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPK 218 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R2P A 14  ? 464 ? P42588 7   ? 457 ? 7   457 
2 2 8R2P A 472 ? 523 ? P38507 218 ? 269 ? 465 516 
3 1 8R2P B 14  ? 464 ? P42588 7   ? 457 ? 7   457 
4 2 8R2P B 472 ? 523 ? P38507 218 ? 269 ? 465 516 
5 1 8R2P C 14  ? 464 ? P42588 7   ? 457 ? 7   457 
6 2 8R2P C 472 ? 523 ? P38507 218 ? 269 ? 465 516 
7 1 8R2P D 14  ? 464 ? P42588 7   ? 457 ? 7   457 
8 2 8R2P D 472 ? 523 ? P38507 218 ? 269 ? 465 516 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R2P GLY A 1   ? UNP P42588 ?   ?   'expression tag'      -6  1  
1 8R2P SER A 2   ? UNP P42588 ?   ?   'expression tag'      -5  2  
1 8R2P SER A 3   ? UNP P42588 ?   ?   'expression tag'      -4  3  
1 8R2P HIS A 4   ? UNP P42588 ?   ?   'expression tag'      -3  4  
1 8R2P HIS A 5   ? UNP P42588 ?   ?   'expression tag'      -2  5  
1 8R2P HIS A 6   ? UNP P42588 ?   ?   'expression tag'      -1  6  
1 8R2P HIS A 7   ? UNP P42588 ?   ?   'expression tag'      0   7  
1 8R2P HIS A 8   ? UNP P42588 ?   ?   'expression tag'      1   8  
1 8R2P HIS A 9   ? UNP P42588 ?   ?   'expression tag'      2   9  
1 8R2P TYR A 10  ? UNP P42588 ?   ?   'expression tag'      3   10 
1 8R2P TYR A 11  ? UNP P42588 ?   ?   'expression tag'      4   11 
1 8R2P LEU A 12  ? UNP P42588 ?   ?   'expression tag'      5   12 
1 8R2P GLU A 13  ? UNP P42588 ?   ?   'expression tag'      6   13 
1 8R2P GLU A 465 ? UNP P42588 ?   ?   linker                458 14 
1 8R2P ALA A 466 ? UNP P42588 ?   ?   linker                459 15 
1 8R2P LEU A 467 ? UNP P42588 ?   ?   linker                460 16 
1 8R2P GLU A 468 ? UNP P42588 ?   ?   linker                461 17 
1 8R2P VAL A 469 ? UNP P42588 ?   ?   linker                462 18 
1 8R2P SER A 470 ? UNP P42588 ?   ?   linker                463 19 
1 8R2P ALA A 471 ? UNP P42588 ?   ?   linker                464 20 
2 8R2P ALA A 494 ? UNP P38507 GLY 240 'engineered mutation' 487 21 
3 8R2P GLY B 1   ? UNP P42588 ?   ?   'expression tag'      -6  22 
3 8R2P SER B 2   ? UNP P42588 ?   ?   'expression tag'      -5  23 
3 8R2P SER B 3   ? UNP P42588 ?   ?   'expression tag'      -4  24 
3 8R2P HIS B 4   ? UNP P42588 ?   ?   'expression tag'      -3  25 
3 8R2P HIS B 5   ? UNP P42588 ?   ?   'expression tag'      -2  26 
3 8R2P HIS B 6   ? UNP P42588 ?   ?   'expression tag'      -1  27 
3 8R2P HIS B 7   ? UNP P42588 ?   ?   'expression tag'      0   28 
3 8R2P HIS B 8   ? UNP P42588 ?   ?   'expression tag'      1   29 
3 8R2P HIS B 9   ? UNP P42588 ?   ?   'expression tag'      2   30 
3 8R2P TYR B 10  ? UNP P42588 ?   ?   'expression tag'      3   31 
3 8R2P TYR B 11  ? UNP P42588 ?   ?   'expression tag'      4   32 
3 8R2P LEU B 12  ? UNP P42588 ?   ?   'expression tag'      5   33 
3 8R2P GLU B 13  ? UNP P42588 ?   ?   'expression tag'      6   34 
3 8R2P GLU B 465 ? UNP P42588 ?   ?   linker                458 35 
3 8R2P ALA B 466 ? UNP P42588 ?   ?   linker                459 36 
3 8R2P LEU B 467 ? UNP P42588 ?   ?   linker                460 37 
3 8R2P GLU B 468 ? UNP P42588 ?   ?   linker                461 38 
3 8R2P VAL B 469 ? UNP P42588 ?   ?   linker                462 39 
3 8R2P SER B 470 ? UNP P42588 ?   ?   linker                463 40 
3 8R2P ALA B 471 ? UNP P42588 ?   ?   linker                464 41 
4 8R2P ALA B 494 ? UNP P38507 GLY 240 'engineered mutation' 487 42 
5 8R2P GLY C 1   ? UNP P42588 ?   ?   'expression tag'      -6  43 
5 8R2P SER C 2   ? UNP P42588 ?   ?   'expression tag'      -5  44 
5 8R2P SER C 3   ? UNP P42588 ?   ?   'expression tag'      -4  45 
5 8R2P HIS C 4   ? UNP P42588 ?   ?   'expression tag'      -3  46 
5 8R2P HIS C 5   ? UNP P42588 ?   ?   'expression tag'      -2  47 
5 8R2P HIS C 6   ? UNP P42588 ?   ?   'expression tag'      -1  48 
5 8R2P HIS C 7   ? UNP P42588 ?   ?   'expression tag'      0   49 
5 8R2P HIS C 8   ? UNP P42588 ?   ?   'expression tag'      1   50 
5 8R2P HIS C 9   ? UNP P42588 ?   ?   'expression tag'      2   51 
5 8R2P TYR C 10  ? UNP P42588 ?   ?   'expression tag'      3   52 
5 8R2P TYR C 11  ? UNP P42588 ?   ?   'expression tag'      4   53 
5 8R2P LEU C 12  ? UNP P42588 ?   ?   'expression tag'      5   54 
5 8R2P GLU C 13  ? UNP P42588 ?   ?   'expression tag'      6   55 
5 8R2P GLU C 465 ? UNP P42588 ?   ?   linker                458 56 
5 8R2P ALA C 466 ? UNP P42588 ?   ?   linker                459 57 
5 8R2P LEU C 467 ? UNP P42588 ?   ?   linker                460 58 
5 8R2P GLU C 468 ? UNP P42588 ?   ?   linker                461 59 
5 8R2P VAL C 469 ? UNP P42588 ?   ?   linker                462 60 
5 8R2P SER C 470 ? UNP P42588 ?   ?   linker                463 61 
5 8R2P ALA C 471 ? UNP P42588 ?   ?   linker                464 62 
6 8R2P ALA C 494 ? UNP P38507 GLY 240 'engineered mutation' 487 63 
7 8R2P GLY D 1   ? UNP P42588 ?   ?   'expression tag'      -6  64 
7 8R2P SER D 2   ? UNP P42588 ?   ?   'expression tag'      -5  65 
7 8R2P SER D 3   ? UNP P42588 ?   ?   'expression tag'      -4  66 
7 8R2P HIS D 4   ? UNP P42588 ?   ?   'expression tag'      -3  67 
7 8R2P HIS D 5   ? UNP P42588 ?   ?   'expression tag'      -2  68 
7 8R2P HIS D 6   ? UNP P42588 ?   ?   'expression tag'      -1  69 
7 8R2P HIS D 7   ? UNP P42588 ?   ?   'expression tag'      0   70 
7 8R2P HIS D 8   ? UNP P42588 ?   ?   'expression tag'      1   71 
7 8R2P HIS D 9   ? UNP P42588 ?   ?   'expression tag'      2   72 
7 8R2P TYR D 10  ? UNP P42588 ?   ?   'expression tag'      3   73 
7 8R2P TYR D 11  ? UNP P42588 ?   ?   'expression tag'      4   74 
7 8R2P LEU D 12  ? UNP P42588 ?   ?   'expression tag'      5   75 
7 8R2P GLU D 13  ? UNP P42588 ?   ?   'expression tag'      6   76 
7 8R2P GLU D 465 ? UNP P42588 ?   ?   linker                458 77 
7 8R2P ALA D 466 ? UNP P42588 ?   ?   linker                459 78 
7 8R2P LEU D 467 ? UNP P42588 ?   ?   linker                460 79 
7 8R2P GLU D 468 ? UNP P42588 ?   ?   linker                461 80 
7 8R2P VAL D 469 ? UNP P42588 ?   ?   linker                462 81 
7 8R2P SER D 470 ? UNP P42588 ?   ?   linker                463 82 
7 8R2P ALA D 471 ? UNP P42588 ?   ?   linker                464 83 
8 8R2P ALA D 494 ? UNP P38507 GLY 240 'engineered mutation' 487 84 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 30690 ? 
1 MORE         -224  ? 
1 'SSA (A^2)'  57510 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 16  ? LYS A 30  ? SER A 9   LYS A 23  1 ? 15 
HELX_P HELX_P2  AA2 ASP A 34  ? VAL A 53  ? ASP A 27  VAL A 46  1 ? 20 
HELX_P HELX_P3  AA3 ASN A 54  ? VAL A 64  ? ASN A 47  VAL A 57  1 ? 11 
HELX_P HELX_P4  AA4 ASN A 107 ? ALA A 119 ? ASN A 100 ALA A 112 1 ? 13 
HELX_P HELX_P5  AA5 ASP A 130 ? THR A 144 ? ASP A 123 THR A 137 1 ? 15 
HELX_P HELX_P6  AA6 SER A 156 ? SER A 173 ? SER A 149 SER A 166 1 ? 18 
HELX_P HELX_P7  AA7 PRO A 174 ? GLY A 176 ? PRO A 167 GLY A 169 5 ? 3  
HELX_P HELX_P8  AA8 SER A 191 ? SER A 196 ? SER A 184 SER A 189 1 ? 6  
HELX_P HELX_P9  AA9 LYS A 200 ? LYS A 205 ? LYS A 193 LYS A 198 1 ? 6  
HELX_P HELX_P10 AB1 PRO A 206 ? MET A 208 ? PRO A 199 MET A 201 5 ? 3  
HELX_P HELX_P11 AB2 ASN A 221 ? THR A 235 ? ASN A 214 THR A 228 1 ? 15 
HELX_P HELX_P12 AB3 GLY A 259 ? GLY A 272 ? GLY A 252 GLY A 265 1 ? 14 
HELX_P HELX_P13 AB4 PHE A 291 ? HIS A 295 ? PHE A 284 HIS A 288 5 ? 5  
HELX_P HELX_P14 AB5 ALA A 306 ? GLY A 311 ? ALA A 299 GLY A 304 5 ? 6  
HELX_P HELX_P15 AB6 GLU A 323 ? SER A 327 ? GLU A 316 SER A 320 1 ? 5  
HELX_P HELX_P16 AB7 VAL A 328 ? PHE A 330 ? VAL A 321 PHE A 323 5 ? 3  
HELX_P HELX_P17 AB8 ASN A 343 ? GLN A 360 ? ASN A 336 GLN A 353 1 ? 18 
HELX_P HELX_P18 AB9 ASN A 361 ? TYR A 384 ? ASN A 354 TYR A 377 1 ? 24 
HELX_P HELX_P19 AC1 ASP A 404 ? GLN A 418 ? ASP A 397 GLN A 411 1 ? 15 
HELX_P HELX_P20 AC2 THR A 441 ? LEU A 467 ? THR A 434 LEU A 460 1 ? 27 
HELX_P HELX_P21 AC3 SER B 16  ? LYS B 30  ? SER B 9   LYS B 23  1 ? 15 
HELX_P HELX_P22 AC4 ASP B 34  ? VAL B 53  ? ASP B 27  VAL B 46  1 ? 20 
HELX_P HELX_P23 AC5 ASN B 54  ? VAL B 64  ? ASN B 47  VAL B 57  1 ? 11 
HELX_P HELX_P24 AC6 ASN B 107 ? ALA B 119 ? ASN B 100 ALA B 112 1 ? 13 
HELX_P HELX_P25 AC7 ASP B 130 ? THR B 144 ? ASP B 123 THR B 137 1 ? 15 
HELX_P HELX_P26 AC8 SER B 156 ? SER B 173 ? SER B 149 SER B 166 1 ? 18 
HELX_P HELX_P27 AC9 PRO B 174 ? GLY B 176 ? PRO B 167 GLY B 169 5 ? 3  
HELX_P HELX_P28 AD1 SER B 191 ? SER B 196 ? SER B 184 SER B 189 1 ? 6  
HELX_P HELX_P29 AD2 LYS B 200 ? LYS B 205 ? LYS B 193 LYS B 198 1 ? 6  
HELX_P HELX_P30 AD3 PRO B 206 ? MET B 208 ? PRO B 199 MET B 201 5 ? 3  
HELX_P HELX_P31 AD4 ASN B 221 ? THR B 235 ? ASN B 214 THR B 228 1 ? 15 
HELX_P HELX_P32 AD5 GLY B 259 ? GLY B 272 ? GLY B 252 GLY B 265 1 ? 14 
HELX_P HELX_P33 AD6 PHE B 291 ? HIS B 295 ? PHE B 284 HIS B 288 5 ? 5  
HELX_P HELX_P34 AD7 ALA B 306 ? GLY B 311 ? ALA B 299 GLY B 304 5 ? 6  
HELX_P HELX_P35 AD8 GLU B 323 ? SER B 327 ? GLU B 316 SER B 320 1 ? 5  
HELX_P HELX_P36 AD9 VAL B 328 ? PHE B 330 ? VAL B 321 PHE B 323 5 ? 3  
HELX_P HELX_P37 AE1 ASN B 343 ? GLN B 360 ? ASN B 336 GLN B 353 1 ? 18 
HELX_P HELX_P38 AE2 ASN B 361 ? TYR B 384 ? ASN B 354 TYR B 377 1 ? 24 
HELX_P HELX_P39 AE3 ASP B 404 ? GLN B 418 ? ASP B 397 GLN B 411 1 ? 15 
HELX_P HELX_P40 AE4 THR B 441 ? ALA B 477 ? THR B 434 ALA B 470 1 ? 37 
HELX_P HELX_P41 AE5 SER C 16  ? LYS C 30  ? SER C 9   LYS C 23  1 ? 15 
HELX_P HELX_P42 AE6 ASP C 34  ? VAL C 53  ? ASP C 27  VAL C 46  1 ? 20 
HELX_P HELX_P43 AE7 ASN C 54  ? VAL C 64  ? ASN C 47  VAL C 57  1 ? 11 
HELX_P HELX_P44 AE8 ASN C 107 ? ALA C 119 ? ASN C 100 ALA C 112 1 ? 13 
HELX_P HELX_P45 AE9 ASP C 130 ? THR C 144 ? ASP C 123 THR C 137 1 ? 15 
HELX_P HELX_P46 AF1 SER C 156 ? SER C 173 ? SER C 149 SER C 166 1 ? 18 
HELX_P HELX_P47 AF2 PRO C 174 ? GLY C 176 ? PRO C 167 GLY C 169 5 ? 3  
HELX_P HELX_P48 AF3 SER C 191 ? SER C 196 ? SER C 184 SER C 189 1 ? 6  
HELX_P HELX_P49 AF4 LYS C 200 ? LYS C 205 ? LYS C 193 LYS C 198 1 ? 6  
HELX_P HELX_P50 AF5 PRO C 206 ? MET C 208 ? PRO C 199 MET C 201 5 ? 3  
HELX_P HELX_P51 AF6 ASN C 221 ? THR C 235 ? ASN C 214 THR C 228 1 ? 15 
HELX_P HELX_P52 AF7 GLY C 259 ? GLY C 272 ? GLY C 252 GLY C 265 1 ? 14 
HELX_P HELX_P53 AF8 PHE C 291 ? HIS C 295 ? PHE C 284 HIS C 288 5 ? 5  
HELX_P HELX_P54 AF9 ALA C 306 ? GLY C 311 ? ALA C 299 GLY C 304 5 ? 6  
HELX_P HELX_P55 AG1 GLU C 323 ? SER C 327 ? GLU C 316 SER C 320 1 ? 5  
HELX_P HELX_P56 AG2 VAL C 328 ? PHE C 330 ? VAL C 321 PHE C 323 5 ? 3  
HELX_P HELX_P57 AG3 ASN C 343 ? GLN C 360 ? ASN C 336 GLN C 353 1 ? 18 
HELX_P HELX_P58 AG4 ASN C 361 ? TYR C 384 ? ASN C 354 TYR C 377 1 ? 24 
HELX_P HELX_P59 AG5 ASP C 404 ? GLN C 418 ? ASP C 397 GLN C 411 1 ? 15 
HELX_P HELX_P60 AG6 THR C 441 ? LYS C 472 ? THR C 434 LYS C 465 1 ? 32 
HELX_P HELX_P61 AG7 SER D 16  ? LYS D 30  ? SER D 9   LYS D 23  1 ? 15 
HELX_P HELX_P62 AG8 ASP D 34  ? VAL D 53  ? ASP D 27  VAL D 46  1 ? 20 
HELX_P HELX_P63 AG9 ASN D 54  ? VAL D 64  ? ASN D 47  VAL D 57  1 ? 11 
HELX_P HELX_P64 AH1 ASN D 107 ? ALA D 119 ? ASN D 100 ALA D 112 1 ? 13 
HELX_P HELX_P65 AH2 ASP D 130 ? THR D 144 ? ASP D 123 THR D 137 1 ? 15 
HELX_P HELX_P66 AH3 SER D 156 ? SER D 173 ? SER D 149 SER D 166 1 ? 18 
HELX_P HELX_P67 AH4 PRO D 174 ? GLY D 176 ? PRO D 167 GLY D 169 5 ? 3  
HELX_P HELX_P68 AH5 SER D 191 ? SER D 196 ? SER D 184 SER D 189 1 ? 6  
HELX_P HELX_P69 AH6 LYS D 200 ? LYS D 205 ? LYS D 193 LYS D 198 1 ? 6  
HELX_P HELX_P70 AH7 PRO D 206 ? MET D 208 ? PRO D 199 MET D 201 5 ? 3  
HELX_P HELX_P71 AH8 ASN D 221 ? THR D 235 ? ASN D 214 THR D 228 1 ? 15 
HELX_P HELX_P72 AH9 GLY D 259 ? GLY D 272 ? GLY D 252 GLY D 265 1 ? 14 
HELX_P HELX_P73 AI1 PHE D 291 ? HIS D 295 ? PHE D 284 HIS D 288 5 ? 5  
HELX_P HELX_P74 AI2 ALA D 306 ? GLY D 311 ? ALA D 299 GLY D 304 5 ? 6  
HELX_P HELX_P75 AI3 GLU D 323 ? SER D 327 ? GLU D 316 SER D 320 1 ? 5  
HELX_P HELX_P76 AI4 VAL D 328 ? PHE D 330 ? VAL D 321 PHE D 323 5 ? 3  
HELX_P HELX_P77 AI5 ASN D 343 ? GLN D 360 ? ASN D 336 GLN D 353 1 ? 18 
HELX_P HELX_P78 AI6 ASN D 361 ? TYR D 384 ? ASN D 354 TYR D 377 1 ? 24 
HELX_P HELX_P79 AI7 ASP D 404 ? GLN D 418 ? ASP D 397 GLN D 411 1 ? 15 
HELX_P HELX_P80 AI8 THR D 441 ? GLU D 465 ? THR D 434 GLU D 458 1 ? 25 
HELX_P HELX_P81 AI9 SER D 470 ? LEU D 484 ? SER D 463 LEU D 477 1 ? 15 
HELX_P HELX_P82 AJ1 ASN D 488 ? ASP D 502 ? ASN D 481 ASP D 495 1 ? 15 
HELX_P HELX_P83 AJ2 GLN D 505 ? ALA D 519 ? GLN D 498 ALA D 512 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 MET 208 A . ? MET 201 A PRO 209 A ? PRO 202 A 1 0.76  
2 MET 208 B . ? MET 201 B PRO 209 B ? PRO 202 B 1 -0.56 
3 MET 208 C . ? MET 201 C PRO 209 C ? PRO 202 C 1 1.64  
4 MET 208 D . ? MET 201 D PRO 209 D ? PRO 202 D 1 0.08  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 7 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 7 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 7 ? 
AB3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA2 6 7 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? parallel      
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA5 6 7 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB2 6 7 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 74  ? ALA A 77  ? GLU A 67  ALA A 70  
AA1 2 THR A 82  ? ASP A 85  ? THR A 75  ASP A 78  
AA1 3 GLU A 90  ? ASP A 93  ? GLU A 83  ASP A 86  
AA1 4 VAL A 420 ? LEU A 421 ? VAL A 413 LEU A 414 
AA2 1 LEU A 148 ? CYS A 154 ? LEU A 141 CYS A 147 
AA2 2 GLY A 317 ? THR A 322 ? GLY A 310 THR A 315 
AA2 3 ILE A 302 ? LEU A 305 ? ILE A 295 LEU A 298 
AA2 4 LEU A 274 ? ASP A 278 ? LEU A 267 ASP A 271 
AA2 5 VAL A 239 ? LEU A 244 ? VAL A 232 LEU A 237 
AA2 6 THR A 179 ? THR A 183 ? THR A 172 THR A 176 
AA2 7 PHE A 214 ? VAL A 217 ? PHE A 207 VAL A 210 
AA3 1 VAL A 388 ? LYS A 394 ? VAL A 381 LYS A 387 
AA3 2 LEU A 397 ? PHE A 402 ? LEU A 390 PHE A 395 
AA3 3 THR A 431 ? ILE A 434 ? THR A 424 ILE A 427 
AA3 4 ALA A 423 ? GLY A 424 ? ALA A 416 GLY A 417 
AA4 1 GLU B 74  ? ALA B 77  ? GLU B 67  ALA B 70  
AA4 2 THR B 82  ? ASP B 85  ? THR B 75  ASP B 78  
AA4 3 GLU B 90  ? ASP B 93  ? GLU B 83  ASP B 86  
AA4 4 VAL B 420 ? LEU B 421 ? VAL B 413 LEU B 414 
AA5 1 LEU B 148 ? CYS B 154 ? LEU B 141 CYS B 147 
AA5 2 GLY B 317 ? THR B 322 ? GLY B 310 THR B 315 
AA5 3 ILE B 302 ? LEU B 305 ? ILE B 295 LEU B 298 
AA5 4 LEU B 274 ? ASP B 278 ? LEU B 267 ASP B 271 
AA5 5 VAL B 239 ? LEU B 244 ? VAL B 232 LEU B 237 
AA5 6 THR B 179 ? THR B 183 ? THR B 172 THR B 176 
AA5 7 PHE B 214 ? VAL B 217 ? PHE B 207 VAL B 210 
AA6 1 VAL B 388 ? LYS B 394 ? VAL B 381 LYS B 387 
AA6 2 LEU B 397 ? PHE B 402 ? LEU B 390 PHE B 395 
AA6 3 THR B 431 ? ILE B 434 ? THR B 424 ILE B 427 
AA6 4 ALA B 423 ? GLY B 424 ? ALA B 416 GLY B 417 
AA7 1 GLU C 74  ? ALA C 77  ? GLU C 67  ALA C 70  
AA7 2 THR C 82  ? ASP C 85  ? THR C 75  ASP C 78  
AA7 3 GLU C 90  ? ASP C 93  ? GLU C 83  ASP C 86  
AA7 4 VAL C 420 ? LEU C 421 ? VAL C 413 LEU C 414 
AA8 1 LEU C 148 ? CYS C 154 ? LEU C 141 CYS C 147 
AA8 2 GLY C 317 ? THR C 322 ? GLY C 310 THR C 315 
AA8 3 ILE C 302 ? LEU C 305 ? ILE C 295 LEU C 298 
AA8 4 LEU C 274 ? ASP C 278 ? LEU C 267 ASP C 271 
AA8 5 VAL C 239 ? LEU C 244 ? VAL C 232 LEU C 237 
AA8 6 THR C 179 ? THR C 183 ? THR C 172 THR C 176 
AA8 7 PHE C 214 ? VAL C 217 ? PHE C 207 VAL C 210 
AA9 1 VAL C 388 ? LYS C 394 ? VAL C 381 LYS C 387 
AA9 2 LEU C 397 ? PHE C 402 ? LEU C 390 PHE C 395 
AA9 3 THR C 431 ? ILE C 434 ? THR C 424 ILE C 427 
AA9 4 ALA C 423 ? GLY C 424 ? ALA C 416 GLY C 417 
AB1 1 GLU D 74  ? ALA D 77  ? GLU D 67  ALA D 70  
AB1 2 THR D 82  ? ASP D 85  ? THR D 75  ASP D 78  
AB1 3 GLU D 90  ? ASP D 93  ? GLU D 83  ASP D 86  
AB1 4 VAL D 420 ? LEU D 421 ? VAL D 413 LEU D 414 
AB2 1 LEU D 148 ? CYS D 154 ? LEU D 141 CYS D 147 
AB2 2 GLY D 317 ? THR D 322 ? GLY D 310 THR D 315 
AB2 3 ILE D 302 ? LEU D 305 ? ILE D 295 LEU D 298 
AB2 4 LEU D 274 ? ASP D 278 ? LEU D 267 ASP D 271 
AB2 5 VAL D 239 ? LEU D 244 ? VAL D 232 LEU D 237 
AB2 6 THR D 179 ? THR D 183 ? THR D 172 THR D 176 
AB2 7 PHE D 214 ? VAL D 217 ? PHE D 207 VAL D 210 
AB3 1 VAL D 388 ? LYS D 394 ? VAL D 381 LYS D 387 
AB3 2 LEU D 397 ? PHE D 402 ? LEU D 390 PHE D 395 
AB3 3 THR D 431 ? ILE D 434 ? THR D 424 ILE D 427 
AB3 4 ALA D 423 ? GLY D 424 ? ALA D 416 GLY D 417 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 76  ? N GLN A 69  O VAL A 84  ? O VAL A 77  
AA1 2 3 N LEU A 83  ? N LEU A 76  O PHE A 91  ? O PHE A 84  
AA1 3 4 N ILE A 92  ? N ILE A 85  O LEU A 421 ? O LEU A 414 
AA2 1 2 N PHE A 152 ? N PHE A 145 O THR A 319 ? O THR A 312 
AA2 2 3 O ILE A 320 ? O ILE A 313 N LEU A 303 ? N LEU A 296 
AA2 3 4 O ILE A 302 ? O ILE A 295 N LEU A 277 ? N LEU A 270 
AA2 4 5 O ILE A 276 ? O ILE A 269 N VAL A 242 ? N VAL A 235 
AA2 5 6 O ALA A 240 ? O ALA A 233 N THR A 179 ? N THR A 172 
AA2 6 7 N ALA A 182 ? N ALA A 175 O ARG A 215 ? O ARG A 208 
AA3 1 2 N GLU A 390 ? N GLU A 383 O GLU A 401 ? O GLU A 394 
AA3 2 3 N MET A 398 ? N MET A 391 O ILE A 434 ? O ILE A 427 
AA3 3 4 O ARG A 433 ? O ARG A 426 N ALA A 423 ? N ALA A 416 
AA4 1 2 N GLN B 76  ? N GLN B 69  O VAL B 84  ? O VAL B 77  
AA4 2 3 N LEU B 83  ? N LEU B 76  O PHE B 91  ? O PHE B 84  
AA4 3 4 N ILE B 92  ? N ILE B 85  O LEU B 421 ? O LEU B 414 
AA5 1 2 N PHE B 152 ? N PHE B 145 O THR B 319 ? O THR B 312 
AA5 2 3 O ILE B 320 ? O ILE B 313 N LEU B 303 ? N LEU B 296 
AA5 3 4 O ILE B 302 ? O ILE B 295 N LEU B 277 ? N LEU B 270 
AA5 4 5 O ILE B 276 ? O ILE B 269 N VAL B 242 ? N VAL B 235 
AA5 5 6 O ALA B 240 ? O ALA B 233 N THR B 179 ? N THR B 172 
AA5 6 7 N ALA B 182 ? N ALA B 175 O ARG B 215 ? O ARG B 208 
AA6 1 2 N GLU B 390 ? N GLU B 383 O GLU B 401 ? O GLU B 394 
AA6 2 3 N MET B 398 ? N MET B 391 O ILE B 434 ? O ILE B 427 
AA6 3 4 O ARG B 433 ? O ARG B 426 N ALA B 423 ? N ALA B 416 
AA7 1 2 N GLN C 76  ? N GLN C 69  O VAL C 84  ? O VAL C 77  
AA7 2 3 N LEU C 83  ? N LEU C 76  O PHE C 91  ? O PHE C 84  
AA7 3 4 N ILE C 92  ? N ILE C 85  O LEU C 421 ? O LEU C 414 
AA8 1 2 N PHE C 152 ? N PHE C 145 O THR C 319 ? O THR C 312 
AA8 2 3 O ILE C 320 ? O ILE C 313 N LEU C 303 ? N LEU C 296 
AA8 3 4 O ILE C 302 ? O ILE C 295 N LEU C 277 ? N LEU C 270 
AA8 4 5 O ILE C 276 ? O ILE C 269 N VAL C 242 ? N VAL C 235 
AA8 5 6 O ALA C 240 ? O ALA C 233 N THR C 179 ? N THR C 172 
AA8 6 7 N ALA C 182 ? N ALA C 175 O ARG C 215 ? O ARG C 208 
AA9 1 2 N GLU C 390 ? N GLU C 383 O GLU C 401 ? O GLU C 394 
AA9 2 3 N MET C 398 ? N MET C 391 O ILE C 434 ? O ILE C 427 
AA9 3 4 O ARG C 433 ? O ARG C 426 N ALA C 423 ? N ALA C 416 
AB1 1 2 N GLN D 76  ? N GLN D 69  O VAL D 84  ? O VAL D 77  
AB1 2 3 N LEU D 83  ? N LEU D 76  O PHE D 91  ? O PHE D 84  
AB1 3 4 N ILE D 92  ? N ILE D 85  O LEU D 421 ? O LEU D 414 
AB2 1 2 N PHE D 152 ? N PHE D 145 O THR D 319 ? O THR D 312 
AB2 2 3 O ILE D 320 ? O ILE D 313 N LEU D 303 ? N LEU D 296 
AB2 3 4 O ILE D 302 ? O ILE D 295 N LEU D 277 ? N LEU D 270 
AB2 4 5 O ILE D 276 ? O ILE D 269 N VAL D 242 ? N VAL D 235 
AB2 5 6 O ALA D 240 ? O ALA D 233 N THR D 179 ? N THR D 172 
AB2 6 7 N ALA D 182 ? N ALA D 175 O ARG D 215 ? O ARG D 208 
AB3 1 2 N GLU D 390 ? N GLU D 383 O GLU D 401 ? O GLU D 394 
AB3 2 3 N MET D 398 ? N MET D 391 O ILE D 434 ? O ILE D 427 
AB3 3 4 O ARG D 433 ? O ARG D 426 N ALA D 423 ? N ALA D 416 
# 
_pdbx_entry_details.entry_id                   8R2P 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O   B HOH 1001 ? ? O  C HOH 947  ? ? 1.69 
2  1 NH2 A ARG 208  ? A O  A HOH 701  ? ? 1.82 
3  1 O   A HOH 713  ? ? O  A HOH 955  ? ? 1.82 
4  1 O   A HOH 889  ? ? O  A HOH 970  ? ? 1.85 
5  1 O   A THR 195  ? ? O  A HOH 702  ? ? 1.85 
6  1 O   B HOH 986  ? ? O  B HOH 1049 ? ? 1.89 
7  1 O   D THR 195  ? ? O  D HOH 701  ? ? 1.89 
8  1 O   D GLU 376  ? ? O  D HOH 702  ? ? 1.90 
9  1 OE2 C GLU 67   ? ? OG D SER 118  ? ? 1.91 
10 1 NH2 C ARG 208  ? A O  C HOH 701  ? ? 1.94 
11 1 O   B HOH 1103 ? ? O  B HOH 1105 ? ? 1.95 
12 1 OE1 D GLN 108  ? A O  D HOH 703  ? ? 1.95 
13 1 O   B LYS 226  ? ? O  B HOH 701  ? ? 1.95 
14 1 O   A HOH 835  ? ? O  B HOH 854  ? ? 1.95 
15 1 O   A HOH 926  ? ? O  D HOH 848  ? ? 1.96 
16 1 O   D HOH 706  ? ? O  D HOH 742  ? ? 1.98 
17 1 O   B HOH 726  ? ? O  B HOH 1016 ? ? 1.98 
18 1 O   D HOH 849  ? ? O  D HOH 939  ? ? 1.98 
19 1 NH1 D ARG 446  ? A O  D HOH 704  ? ? 1.99 
20 1 O   A HOH 862  ? ? O  A HOH 993  ? ? 2.05 
21 1 O   C HOH 747  ? ? O  C HOH 869  ? ? 2.05 
22 1 O   A HOH 970  ? ? O  D HOH 936  ? ? 2.05 
23 1 O   B HOH 980  ? ? O  B HOH 1033 ? ? 2.07 
24 1 O   A HOH 995  ? ? O  D HOH 1092 ? ? 2.07 
25 1 O   A PRO 48   ? ? O  A HOH 703  ? ? 2.08 
26 1 OD1 D ASN 19   ? A O  D HOH 705  ? ? 2.08 
27 1 O   B PHE 212  ? ? O  B HOH 702  ? ? 2.08 
28 1 OE1 A GLN 353  ? ? O  A HOH 704  ? ? 2.08 
29 1 O   B THR 195  ? ? O  B HOH 703  ? ? 2.08 
30 1 O   D HOH 721  ? ? O  D HOH 762  ? ? 2.09 
31 1 O   A HOH 770  ? ? O  A HOH 968  ? ? 2.09 
32 1 O   A GLU 376  ? ? O  A HOH 705  ? ? 2.10 
33 1 O   D HOH 839  ? ? O  D HOH 1017 ? ? 2.10 
34 1 O   A HOH 754  ? ? O  A HOH 999  ? ? 2.11 
35 1 O   B HOH 882  ? ? O  B HOH 978  ? ? 2.12 
36 1 O   D HOH 735  ? ? O  D HOH 1083 ? ? 2.12 
37 1 O   C LEU 141  ? ? O  C HOH 702  ? ? 2.12 
38 1 O   C HOH 930  ? ? O  C HOH 1018 ? ? 2.12 
39 1 O   A HOH 927  ? ? O  A HOH 943  ? ? 2.13 
40 1 O   B HOH 929  ? ? O  C HOH 704  ? ? 2.13 
41 1 O   A HOH 923  ? ? O  A HOH 1015 ? ? 2.13 
42 1 OE2 A GLU 263  ? ? O  A HOH 706  ? ? 2.14 
43 1 O   D THR 137  ? ? O  D HOH 706  ? ? 2.14 
44 1 O   A GLU 458  ? ? N  A LEU 460  ? ? 2.14 
45 1 O   B GLU 376  ? ? O  B HOH 704  ? ? 2.14 
46 1 O   A LYS 282  ? ? O  A HOH 707  ? ? 2.14 
47 1 O   B HOH 712  ? ? O  B HOH 943  ? ? 2.14 
48 1 O   B HOH 795  ? ? O  B HOH 1064 ? ? 2.15 
49 1 O   B HOH 1073 ? ? O  B HOH 1101 ? ? 2.16 
50 1 O   D HOH 1079 ? ? O  D HOH 1102 ? ? 2.16 
51 1 O   B PRO 251  ? ? O  B HOH 705  ? ? 2.16 
52 1 OE1 C GLN 108  ? A O  C HOH 703  ? ? 2.16 
53 1 O   B HOH 888  ? ? O  C HOH 794  ? ? 2.17 
54 1 O   B VAL 102  ? ? O  B HOH 706  ? ? 2.17 
55 1 O   B ALA 134  ? ? O  B HOH 707  ? ? 2.18 
56 1 OE1 D GLU 482  ? ? O  D HOH 707  ? ? 2.18 
57 1 O   B HOH 1016 ? ? O  C HOH 794  ? ? 2.18 
58 1 OE1 A GLN 108  ? B O  A HOH 708  ? ? 2.18 
59 1 O   B ARG 36   ? ? O  B HOH 708  ? ? 2.18 
60 1 O   D HOH 1021 ? ? O  D HOH 1068 ? ? 2.19 
61 1 O   A THR 330  ? ? O  A HOH 709  ? ? 2.19 
62 1 O   D ARG 36   ? ? O  D HOH 708  ? ? 2.19 
63 1 O   C HOH 757  ? ? O  C HOH 928  ? ? 2.19 
64 1 O   C LYS 226  ? ? O  C HOH 704  ? ? 2.19 
65 1 O   C HOH 811  ? ? O  C HOH 829  ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 45  ? ? -144.11 -9.42   
2  1 ASN A 47  ? ? -179.98 105.80  
3  1 TRP A 68  ? ? -131.39 -55.67  
4  1 SER A 72  ? ? -115.62 -169.14 
5  1 PHE A 94  ? ? -90.46  52.05   
6  1 LYS A 113 ? ? -105.49 -61.58  
7  1 GLN A 114 ? ? -162.98 99.66   
8  1 GLU A 120 ? ? -121.47 -51.71  
9  1 LYS A 142 ? ? -138.57 -36.29  
10 1 ASP A 230 ? ? -110.18 50.26   
11 1 ALA A 299 ? ? -163.11 -141.23 
12 1 LYS A 300 ? ? 41.68   -102.03 
13 1 VAL A 306 ? ? -122.49 -50.45  
14 1 SER A 320 ? ? -56.57  -9.77   
15 1 ASN A 420 ? ? -83.59  36.12   
16 1 ASN A 421 ? ? -173.14 107.36  
17 1 GLU A 458 ? ? -46.85  -105.07 
18 1 ALA A 459 ? ? 13.81   -63.28  
19 1 HIS B 45  ? ? -143.85 -9.32   
20 1 ASN B 47  ? ? -179.52 106.75  
21 1 TRP B 68  ? ? -131.12 -55.73  
22 1 SER B 72  ? ? -114.89 -169.29 
23 1 LYS B 113 ? ? -104.57 -61.80  
24 1 GLN B 114 ? ? -163.64 100.30  
25 1 LYS B 142 ? ? -139.27 -37.45  
26 1 ASP B 230 ? ? -111.33 51.62   
27 1 VAL B 246 ? ? 59.83   70.51   
28 1 ALA B 299 ? ? -163.60 -141.52 
29 1 LYS B 300 ? ? 40.75   -101.22 
30 1 VAL B 306 ? ? -121.95 -51.74  
31 1 ASN B 420 ? ? -83.42  36.62   
32 1 ASN B 421 ? ? -173.58 108.05  
33 1 HIS C 45  ? ? -144.79 -9.20   
34 1 ASN C 47  ? ? 179.45  106.08  
35 1 TRP C 68  ? ? -131.27 -55.18  
36 1 SER C 72  ? ? -115.17 -169.59 
37 1 LYS C 113 ? ? -105.60 -61.37  
38 1 GLN C 114 ? ? -164.44 100.17  
39 1 GLU C 120 ? ? -120.83 -52.07  
40 1 LYS C 142 ? ? -140.02 -36.53  
41 1 ASP C 230 ? ? -110.20 50.32   
42 1 VAL C 246 ? ? 58.05   70.52   
43 1 ALA C 299 ? ? -163.15 -141.94 
44 1 LYS C 300 ? ? 41.15   -101.71 
45 1 VAL C 306 ? ? -122.39 -50.38  
46 1 ASN C 420 ? ? -84.51  36.26   
47 1 ASN C 421 ? ? -171.31 107.92  
48 1 VAL C 462 ? ? -61.33  0.39    
49 1 HIS D 45  ? ? -144.10 -8.13   
50 1 ASN D 47  ? ? -179.46 105.53  
51 1 TRP D 68  ? ? -130.87 -55.99  
52 1 SER D 72  ? ? -115.30 -168.70 
53 1 PHE D 94  ? ? -90.26  53.02   
54 1 LYS D 113 ? ? -104.46 -61.51  
55 1 GLN D 114 ? ? -163.96 100.93  
56 1 LYS D 142 ? ? -138.02 -37.62  
57 1 ASP D 230 ? ? -110.57 50.86   
58 1 VAL D 246 ? ? 59.24   70.67   
59 1 ALA D 299 ? ? -162.92 -143.06 
60 1 LYS D 300 ? ? 41.89   -101.57 
61 1 VAL D 306 ? ? -120.84 -51.34  
62 1 ASN D 420 ? ? -83.78  36.62   
63 1 ASN D 421 ? ? -173.13 107.67  
64 1 GLU D 458 ? ? -51.31  80.17   
65 1 ALA D 459 ? ? 30.78   60.36   
66 1 GLU D 461 ? ? 158.37  -70.23  
67 1 SER D 463 ? ? 179.43  9.33    
68 1 ALA D 464 ? ? -48.61  -75.49  
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1042 ? 5.91 . 
2 1 O ? A HOH 1043 ? 5.93 . 
3 1 O ? A HOH 1044 ? 7.26 . 
4 1 O ? A HOH 1045 ? 7.68 . 
5 1 O ? A HOH 1046 ? 8.21 . 
6 1 O ? B HOH 1106 ? 6.79 . 
7 1 O ? D HOH 1105 ? 5.89 . 
8 1 O ? D HOH 1106 ? 6.01 . 
9 1 O ? D HOH 1107 ? 6.12 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY -6  ? A GLY 1   
2   1 Y 1 A SER -5  ? A SER 2   
3   1 Y 1 A SER -4  ? A SER 3   
4   1 Y 1 A HIS -3  ? A HIS 4   
5   1 Y 1 A HIS -2  ? A HIS 5   
6   1 Y 1 A HIS -1  ? A HIS 6   
7   1 Y 1 A HIS 0   ? A HIS 7   
8   1 Y 1 A HIS 1   ? A HIS 8   
9   1 Y 1 A HIS 2   ? A HIS 9   
10  1 Y 1 A TYR 3   ? A TYR 10  
11  1 Y 1 A TYR 4   ? A TYR 11  
12  1 Y 1 A LEU 5   ? A LEU 12  
13  1 Y 1 A GLU 6   ? A GLU 13  
14  1 Y 1 A SER 7   ? A SER 14  
15  1 Y 1 A GLU 461 ? A GLU 468 
16  1 Y 1 A VAL 462 ? A VAL 469 
17  1 Y 1 A SER 463 ? A SER 470 
18  1 Y 1 A ALA 464 ? A ALA 471 
19  1 Y 1 A LYS 465 ? A LYS 472 
20  1 Y 1 A GLU 466 ? A GLU 473 
21  1 Y 1 A GLN 467 ? A GLN 474 
22  1 Y 1 A GLN 468 ? A GLN 475 
23  1 Y 1 A ASN 469 ? A ASN 476 
24  1 Y 1 A ALA 470 ? A ALA 477 
25  1 Y 1 A PHE 471 ? A PHE 478 
26  1 Y 1 A TYR 472 ? A TYR 479 
27  1 Y 1 A GLU 473 ? A GLU 480 
28  1 Y 1 A ILE 474 ? A ILE 481 
29  1 Y 1 A LEU 475 ? A LEU 482 
30  1 Y 1 A HIS 476 ? A HIS 483 
31  1 Y 1 A LEU 477 ? A LEU 484 
32  1 Y 1 A PRO 478 ? A PRO 485 
33  1 Y 1 A ASN 479 ? A ASN 486 
34  1 Y 1 A LEU 480 ? A LEU 487 
35  1 Y 1 A ASN 481 ? A ASN 488 
36  1 Y 1 A GLU 482 ? A GLU 489 
37  1 Y 1 A GLU 483 ? A GLU 490 
38  1 Y 1 A GLN 484 ? A GLN 491 
39  1 Y 1 A ARG 485 ? A ARG 492 
40  1 Y 1 A ASN 486 ? A ASN 493 
41  1 Y 1 A ALA 487 ? A ALA 494 
42  1 Y 1 A PHE 488 ? A PHE 495 
43  1 Y 1 A ILE 489 ? A ILE 496 
44  1 Y 1 A GLN 490 ? A GLN 497 
45  1 Y 1 A SER 491 ? A SER 498 
46  1 Y 1 A LEU 492 ? A LEU 499 
47  1 Y 1 A LYS 493 ? A LYS 500 
48  1 Y 1 A ASP 494 ? A ASP 501 
49  1 Y 1 A ASP 495 ? A ASP 502 
50  1 Y 1 A PRO 496 ? A PRO 503 
51  1 Y 1 A SER 497 ? A SER 504 
52  1 Y 1 A GLN 498 ? A GLN 505 
53  1 Y 1 A SER 499 ? A SER 506 
54  1 Y 1 A ALA 500 ? A ALA 507 
55  1 Y 1 A ASN 501 ? A ASN 508 
56  1 Y 1 A LEU 502 ? A LEU 509 
57  1 Y 1 A LEU 503 ? A LEU 510 
58  1 Y 1 A ALA 504 ? A ALA 511 
59  1 Y 1 A GLU 505 ? A GLU 512 
60  1 Y 1 A ALA 506 ? A ALA 513 
61  1 Y 1 A LYS 507 ? A LYS 514 
62  1 Y 1 A LYS 508 ? A LYS 515 
63  1 Y 1 A LEU 509 ? A LEU 516 
64  1 Y 1 A ASN 510 ? A ASN 517 
65  1 Y 1 A ASP 511 ? A ASP 518 
66  1 Y 1 A ALA 512 ? A ALA 519 
67  1 Y 1 A GLN 513 ? A GLN 520 
68  1 Y 1 A ALA 514 ? A ALA 521 
69  1 Y 1 A PRO 515 ? A PRO 522 
70  1 Y 1 A LYS 516 ? A LYS 523 
71  1 Y 1 B GLY -6  ? B GLY 1   
72  1 Y 1 B SER -5  ? B SER 2   
73  1 Y 1 B SER -4  ? B SER 3   
74  1 Y 1 B HIS -3  ? B HIS 4   
75  1 Y 1 B HIS -2  ? B HIS 5   
76  1 Y 1 B HIS -1  ? B HIS 6   
77  1 Y 1 B HIS 0   ? B HIS 7   
78  1 Y 1 B HIS 1   ? B HIS 8   
79  1 Y 1 B HIS 2   ? B HIS 9   
80  1 Y 1 B TYR 3   ? B TYR 10  
81  1 Y 1 B TYR 4   ? B TYR 11  
82  1 Y 1 B LEU 5   ? B LEU 12  
83  1 Y 1 B GLU 6   ? B GLU 13  
84  1 Y 1 B SER 7   ? B SER 14  
85  1 Y 1 B PHE 471 ? B PHE 478 
86  1 Y 1 B TYR 472 ? B TYR 479 
87  1 Y 1 B GLU 473 ? B GLU 480 
88  1 Y 1 B ILE 474 ? B ILE 481 
89  1 Y 1 B LEU 475 ? B LEU 482 
90  1 Y 1 B HIS 476 ? B HIS 483 
91  1 Y 1 B LEU 477 ? B LEU 484 
92  1 Y 1 B PRO 478 ? B PRO 485 
93  1 Y 1 B ASN 479 ? B ASN 486 
94  1 Y 1 B LEU 480 ? B LEU 487 
95  1 Y 1 B ASN 481 ? B ASN 488 
96  1 Y 1 B GLU 482 ? B GLU 489 
97  1 Y 1 B GLU 483 ? B GLU 490 
98  1 Y 1 B GLN 484 ? B GLN 491 
99  1 Y 1 B ARG 485 ? B ARG 492 
100 1 Y 1 B ASN 486 ? B ASN 493 
101 1 Y 1 B ALA 487 ? B ALA 494 
102 1 Y 1 B PHE 488 ? B PHE 495 
103 1 Y 1 B ILE 489 ? B ILE 496 
104 1 Y 1 B GLN 490 ? B GLN 497 
105 1 Y 1 B SER 491 ? B SER 498 
106 1 Y 1 B LEU 492 ? B LEU 499 
107 1 Y 1 B LYS 493 ? B LYS 500 
108 1 Y 1 B ASP 494 ? B ASP 501 
109 1 Y 1 B ASP 495 ? B ASP 502 
110 1 Y 1 B PRO 496 ? B PRO 503 
111 1 Y 1 B SER 497 ? B SER 504 
112 1 Y 1 B GLN 498 ? B GLN 505 
113 1 Y 1 B SER 499 ? B SER 506 
114 1 Y 1 B ALA 500 ? B ALA 507 
115 1 Y 1 B ASN 501 ? B ASN 508 
116 1 Y 1 B LEU 502 ? B LEU 509 
117 1 Y 1 B LEU 503 ? B LEU 510 
118 1 Y 1 B ALA 504 ? B ALA 511 
119 1 Y 1 B GLU 505 ? B GLU 512 
120 1 Y 1 B ALA 506 ? B ALA 513 
121 1 Y 1 B LYS 507 ? B LYS 514 
122 1 Y 1 B LYS 508 ? B LYS 515 
123 1 Y 1 B LEU 509 ? B LEU 516 
124 1 Y 1 B ASN 510 ? B ASN 517 
125 1 Y 1 B ASP 511 ? B ASP 518 
126 1 Y 1 B ALA 512 ? B ALA 519 
127 1 Y 1 B GLN 513 ? B GLN 520 
128 1 Y 1 B ALA 514 ? B ALA 521 
129 1 Y 1 B PRO 515 ? B PRO 522 
130 1 Y 1 B LYS 516 ? B LYS 523 
131 1 Y 1 C GLY -6  ? C GLY 1   
132 1 Y 1 C SER -5  ? C SER 2   
133 1 Y 1 C SER -4  ? C SER 3   
134 1 Y 1 C HIS -3  ? C HIS 4   
135 1 Y 1 C HIS -2  ? C HIS 5   
136 1 Y 1 C HIS -1  ? C HIS 6   
137 1 Y 1 C HIS 0   ? C HIS 7   
138 1 Y 1 C HIS 1   ? C HIS 8   
139 1 Y 1 C HIS 2   ? C HIS 9   
140 1 Y 1 C TYR 3   ? C TYR 10  
141 1 Y 1 C TYR 4   ? C TYR 11  
142 1 Y 1 C LEU 5   ? C LEU 12  
143 1 Y 1 C GLU 6   ? C GLU 13  
144 1 Y 1 C SER 7   ? C SER 14  
145 1 Y 1 C ASN 469 ? C ASN 476 
146 1 Y 1 C ALA 470 ? C ALA 477 
147 1 Y 1 C PHE 471 ? C PHE 478 
148 1 Y 1 C TYR 472 ? C TYR 479 
149 1 Y 1 C GLU 473 ? C GLU 480 
150 1 Y 1 C ILE 474 ? C ILE 481 
151 1 Y 1 C LEU 475 ? C LEU 482 
152 1 Y 1 C HIS 476 ? C HIS 483 
153 1 Y 1 C LEU 477 ? C LEU 484 
154 1 Y 1 C PRO 478 ? C PRO 485 
155 1 Y 1 C ASN 479 ? C ASN 486 
156 1 Y 1 C LEU 480 ? C LEU 487 
157 1 Y 1 C ASN 481 ? C ASN 488 
158 1 Y 1 C GLU 482 ? C GLU 489 
159 1 Y 1 C GLU 483 ? C GLU 490 
160 1 Y 1 C GLN 484 ? C GLN 491 
161 1 Y 1 C ARG 485 ? C ARG 492 
162 1 Y 1 C ASN 486 ? C ASN 493 
163 1 Y 1 C ALA 487 ? C ALA 494 
164 1 Y 1 C PHE 488 ? C PHE 495 
165 1 Y 1 C ILE 489 ? C ILE 496 
166 1 Y 1 C GLN 490 ? C GLN 497 
167 1 Y 1 C SER 491 ? C SER 498 
168 1 Y 1 C LEU 492 ? C LEU 499 
169 1 Y 1 C LYS 493 ? C LYS 500 
170 1 Y 1 C ASP 494 ? C ASP 501 
171 1 Y 1 C ASP 495 ? C ASP 502 
172 1 Y 1 C PRO 496 ? C PRO 503 
173 1 Y 1 C SER 497 ? C SER 504 
174 1 Y 1 C GLN 498 ? C GLN 505 
175 1 Y 1 C SER 499 ? C SER 506 
176 1 Y 1 C ALA 500 ? C ALA 507 
177 1 Y 1 C ASN 501 ? C ASN 508 
178 1 Y 1 C LEU 502 ? C LEU 509 
179 1 Y 1 C LEU 503 ? C LEU 510 
180 1 Y 1 C ALA 504 ? C ALA 511 
181 1 Y 1 C GLU 505 ? C GLU 512 
182 1 Y 1 C ALA 506 ? C ALA 513 
183 1 Y 1 C LYS 507 ? C LYS 514 
184 1 Y 1 C LYS 508 ? C LYS 515 
185 1 Y 1 C LEU 509 ? C LEU 516 
186 1 Y 1 C ASN 510 ? C ASN 517 
187 1 Y 1 C ASP 511 ? C ASP 518 
188 1 Y 1 C ALA 512 ? C ALA 519 
189 1 Y 1 C GLN 513 ? C GLN 520 
190 1 Y 1 C ALA 514 ? C ALA 521 
191 1 Y 1 C PRO 515 ? C PRO 522 
192 1 Y 1 C LYS 516 ? C LYS 523 
193 1 Y 1 D GLY -6  ? D GLY 1   
194 1 Y 1 D SER -5  ? D SER 2   
195 1 Y 1 D SER -4  ? D SER 3   
196 1 Y 1 D HIS -3  ? D HIS 4   
197 1 Y 1 D HIS -2  ? D HIS 5   
198 1 Y 1 D HIS -1  ? D HIS 6   
199 1 Y 1 D HIS 0   ? D HIS 7   
200 1 Y 1 D HIS 1   ? D HIS 8   
201 1 Y 1 D HIS 2   ? D HIS 9   
202 1 Y 1 D TYR 3   ? D TYR 10  
203 1 Y 1 D TYR 4   ? D TYR 11  
204 1 Y 1 D LEU 5   ? D LEU 12  
205 1 Y 1 D GLU 6   ? D GLU 13  
206 1 Y 1 D SER 7   ? D SER 14  
207 1 Y 1 D PRO 515 ? D PRO 522 
208 1 Y 1 D LYS 516 ? D LYS 523 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PLP N1   N Y N 273 
PLP C2   C Y N 274 
PLP C2A  C N N 275 
PLP C3   C Y N 276 
PLP O3   O N N 277 
PLP C4   C Y N 278 
PLP C4A  C N N 279 
PLP O4A  O N N 280 
PLP C5   C Y N 281 
PLP C6   C Y N 282 
PLP C5A  C N N 283 
PLP O4P  O N N 284 
PLP P    P N N 285 
PLP O1P  O N N 286 
PLP O2P  O N N 287 
PLP O3P  O N N 288 
PLP H2A1 H N N 289 
PLP H2A2 H N N 290 
PLP H2A3 H N N 291 
PLP HO3  H N N 292 
PLP H4A  H N N 293 
PLP H6   H N N 294 
PLP H5A1 H N N 295 
PLP H5A2 H N N 296 
PLP HOP2 H N N 297 
PLP HOP3 H N N 298 
PRO N    N N N 299 
PRO CA   C N S 300 
PRO C    C N N 301 
PRO O    O N N 302 
PRO CB   C N N 303 
PRO CG   C N N 304 
PRO CD   C N N 305 
PRO OXT  O N N 306 
PRO H    H N N 307 
PRO HA   H N N 308 
PRO HB2  H N N 309 
PRO HB3  H N N 310 
PRO HG2  H N N 311 
PRO HG3  H N N 312 
PRO HD2  H N N 313 
PRO HD3  H N N 314 
PRO HXT  H N N 315 
SER N    N N N 316 
SER CA   C N S 317 
SER C    C N N 318 
SER O    O N N 319 
SER CB   C N N 320 
SER OG   O N N 321 
SER OXT  O N N 322 
SER H    H N N 323 
SER H2   H N N 324 
SER HA   H N N 325 
SER HB2  H N N 326 
SER HB3  H N N 327 
SER HG   H N N 328 
SER HXT  H N N 329 
THR N    N N N 330 
THR CA   C N S 331 
THR C    C N N 332 
THR O    O N N 333 
THR CB   C N R 334 
THR OG1  O N N 335 
THR CG2  C N N 336 
THR OXT  O N N 337 
THR H    H N N 338 
THR H2   H N N 339 
THR HA   H N N 340 
THR HB   H N N 341 
THR HG1  H N N 342 
THR HG21 H N N 343 
THR HG22 H N N 344 
THR HG23 H N N 345 
THR HXT  H N N 346 
TRP N    N N N 347 
TRP CA   C N S 348 
TRP C    C N N 349 
TRP O    O N N 350 
TRP CB   C N N 351 
TRP CG   C Y N 352 
TRP CD1  C Y N 353 
TRP CD2  C Y N 354 
TRP NE1  N Y N 355 
TRP CE2  C Y N 356 
TRP CE3  C Y N 357 
TRP CZ2  C Y N 358 
TRP CZ3  C Y N 359 
TRP CH2  C Y N 360 
TRP OXT  O N N 361 
TRP H    H N N 362 
TRP H2   H N N 363 
TRP HA   H N N 364 
TRP HB2  H N N 365 
TRP HB3  H N N 366 
TRP HD1  H N N 367 
TRP HE1  H N N 368 
TRP HE3  H N N 369 
TRP HZ2  H N N 370 
TRP HZ3  H N N 371 
TRP HH2  H N N 372 
TRP HXT  H N N 373 
TYR N    N N N 374 
TYR CA   C N S 375 
TYR C    C N N 376 
TYR O    O N N 377 
TYR CB   C N N 378 
TYR CG   C Y N 379 
TYR CD1  C Y N 380 
TYR CD2  C Y N 381 
TYR CE1  C Y N 382 
TYR CE2  C Y N 383 
TYR CZ   C Y N 384 
TYR OH   O N N 385 
TYR OXT  O N N 386 
TYR H    H N N 387 
TYR H2   H N N 388 
TYR HA   H N N 389 
TYR HB2  H N N 390 
TYR HB3  H N N 391 
TYR HD1  H N N 392 
TYR HD2  H N N 393 
TYR HE1  H N N 394 
TYR HE2  H N N 395 
TYR HH   H N N 396 
TYR HXT  H N N 397 
VAL N    N N N 398 
VAL CA   C N S 399 
VAL C    C N N 400 
VAL O    O N N 401 
VAL CB   C N N 402 
VAL CG1  C N N 403 
VAL CG2  C N N 404 
VAL OXT  O N N 405 
VAL H    H N N 406 
VAL H2   H N N 407 
VAL HA   H N N 408 
VAL HB   H N N 409 
VAL HG11 H N N 410 
VAL HG12 H N N 411 
VAL HG13 H N N 412 
VAL HG21 H N N 413 
VAL HG22 H N N 414 
VAL HG23 H N N 415 
VAL HXT  H N N 416 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PLP N1  C2   doub Y N 260 
PLP N1  C6   sing Y N 261 
PLP C2  C2A  sing N N 262 
PLP C2  C3   sing Y N 263 
PLP C2A H2A1 sing N N 264 
PLP C2A H2A2 sing N N 265 
PLP C2A H2A3 sing N N 266 
PLP C3  O3   sing N N 267 
PLP C3  C4   doub Y N 268 
PLP O3  HO3  sing N N 269 
PLP C4  C4A  sing N N 270 
PLP C4  C5   sing Y N 271 
PLP C4A O4A  doub N N 272 
PLP C4A H4A  sing N N 273 
PLP C5  C6   doub Y N 274 
PLP C5  C5A  sing N N 275 
PLP C6  H6   sing N N 276 
PLP C5A O4P  sing N N 277 
PLP C5A H5A1 sing N N 278 
PLP C5A H5A2 sing N N 279 
PLP O4P P    sing N N 280 
PLP P   O1P  doub N N 281 
PLP P   O2P  sing N N 282 
PLP P   O3P  sing N N 283 
PLP O2P HOP2 sing N N 284 
PLP O3P HOP3 sing N N 285 
PRO N   CA   sing N N 286 
PRO N   CD   sing N N 287 
PRO N   H    sing N N 288 
PRO CA  C    sing N N 289 
PRO CA  CB   sing N N 290 
PRO CA  HA   sing N N 291 
PRO C   O    doub N N 292 
PRO C   OXT  sing N N 293 
PRO CB  CG   sing N N 294 
PRO CB  HB2  sing N N 295 
PRO CB  HB3  sing N N 296 
PRO CG  CD   sing N N 297 
PRO CG  HG2  sing N N 298 
PRO CG  HG3  sing N N 299 
PRO CD  HD2  sing N N 300 
PRO CD  HD3  sing N N 301 
PRO OXT HXT  sing N N 302 
SER N   CA   sing N N 303 
SER N   H    sing N N 304 
SER N   H2   sing N N 305 
SER CA  C    sing N N 306 
SER CA  CB   sing N N 307 
SER CA  HA   sing N N 308 
SER C   O    doub N N 309 
SER C   OXT  sing N N 310 
SER CB  OG   sing N N 311 
SER CB  HB2  sing N N 312 
SER CB  HB3  sing N N 313 
SER OG  HG   sing N N 314 
SER OXT HXT  sing N N 315 
THR N   CA   sing N N 316 
THR N   H    sing N N 317 
THR N   H2   sing N N 318 
THR CA  C    sing N N 319 
THR CA  CB   sing N N 320 
THR CA  HA   sing N N 321 
THR C   O    doub N N 322 
THR C   OXT  sing N N 323 
THR CB  OG1  sing N N 324 
THR CB  CG2  sing N N 325 
THR CB  HB   sing N N 326 
THR OG1 HG1  sing N N 327 
THR CG2 HG21 sing N N 328 
THR CG2 HG22 sing N N 329 
THR CG2 HG23 sing N N 330 
THR OXT HXT  sing N N 331 
TRP N   CA   sing N N 332 
TRP N   H    sing N N 333 
TRP N   H2   sing N N 334 
TRP CA  C    sing N N 335 
TRP CA  CB   sing N N 336 
TRP CA  HA   sing N N 337 
TRP C   O    doub N N 338 
TRP C   OXT  sing N N 339 
TRP CB  CG   sing N N 340 
TRP CB  HB2  sing N N 341 
TRP CB  HB3  sing N N 342 
TRP CG  CD1  doub Y N 343 
TRP CG  CD2  sing Y N 344 
TRP CD1 NE1  sing Y N 345 
TRP CD1 HD1  sing N N 346 
TRP CD2 CE2  doub Y N 347 
TRP CD2 CE3  sing Y N 348 
TRP NE1 CE2  sing Y N 349 
TRP NE1 HE1  sing N N 350 
TRP CE2 CZ2  sing Y N 351 
TRP CE3 CZ3  doub Y N 352 
TRP CE3 HE3  sing N N 353 
TRP CZ2 CH2  doub Y N 354 
TRP CZ2 HZ2  sing N N 355 
TRP CZ3 CH2  sing Y N 356 
TRP CZ3 HZ3  sing N N 357 
TRP CH2 HH2  sing N N 358 
TRP OXT HXT  sing N N 359 
TYR N   CA   sing N N 360 
TYR N   H    sing N N 361 
TYR N   H2   sing N N 362 
TYR CA  C    sing N N 363 
TYR CA  CB   sing N N 364 
TYR CA  HA   sing N N 365 
TYR C   O    doub N N 366 
TYR C   OXT  sing N N 367 
TYR CB  CG   sing N N 368 
TYR CB  HB2  sing N N 369 
TYR CB  HB3  sing N N 370 
TYR CG  CD1  doub Y N 371 
TYR CG  CD2  sing Y N 372 
TYR CD1 CE1  sing Y N 373 
TYR CD1 HD1  sing N N 374 
TYR CD2 CE2  doub Y N 375 
TYR CD2 HD2  sing N N 376 
TYR CE1 CZ   doub Y N 377 
TYR CE1 HE1  sing N N 378 
TYR CE2 CZ   sing Y N 379 
TYR CE2 HE2  sing N N 380 
TYR CZ  OH   sing N N 381 
TYR OH  HH   sing N N 382 
TYR OXT HXT  sing N N 383 
VAL N   CA   sing N N 384 
VAL N   H    sing N N 385 
VAL N   H2   sing N N 386 
VAL CA  C    sing N N 387 
VAL CA  CB   sing N N 388 
VAL CA  HA   sing N N 389 
VAL C   O    doub N N 390 
VAL C   OXT  sing N N 391 
VAL CB  CG1  sing N N 392 
VAL CB  CG2  sing N N 393 
VAL CB  HB   sing N N 394 
VAL CG1 HG11 sing N N 395 
VAL CG1 HG12 sing N N 396 
VAL CG1 HG13 sing N N 397 
VAL CG2 HG21 sing N N 398 
VAL CG2 HG22 sing N N 399 
VAL CG2 HG23 sing N N 400 
VAL OXT HXT  sing N N 401 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Clas Groschinsky Memorial Fund'    Sweden M19380 1 
'Sven and Dagmar Salens Foundation' Sweden ?      2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8CPL 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8R2P 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013650 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.005082 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004806 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ALA A 1 15  ? 27.049  26.019  -14.373  1.00 93.45  ? 8    ALA A N   1 
ATOM   2     C CA  . ALA A 1 15  ? 28.000  25.164  -13.594  1.00 89.89  ? 8    ALA A CA  1 
ATOM   3     C C   . ALA A 1 15  ? 28.328  23.890  -14.388  1.00 78.52  ? 8    ALA A C   1 
ATOM   4     O O   . ALA A 1 15  ? 27.657  23.605  -15.411  1.00 67.33  ? 8    ALA A O   1 
ATOM   5     C CB  . ALA A 1 15  ? 27.415  24.844  -12.231  1.00 91.05  ? 8    ALA A CB  1 
ATOM   6     N N   . SER A 1 16  ? 29.343  23.150  -13.939  1.00 66.01  ? 9    SER A N   1 
ATOM   7     C CA  . SER A 1 16  ? 29.631  21.778  -14.426  1.00 57.45  ? 9    SER A CA  1 
ATOM   8     C C   . SER A 1 16  ? 28.477  20.862  -13.996  1.00 50.02  ? 9    SER A C   1 
ATOM   9     O O   . SER A 1 16  ? 27.724  21.215  -13.061  1.00 45.14  ? 9    SER A O   1 
ATOM   10    C CB  . SER A 1 16  ? 30.978  21.288  -13.938  1.00 58.62  ? 9    SER A CB  1 
ATOM   11    O OG  . SER A 1 16  ? 30.932  20.931  -12.564  1.00 59.76  ? 9    SER A OG  1 
ATOM   12    N N   . ALA A 1 17  ? 28.319  19.734  -14.678  1.00 43.33  ? 10   ALA A N   1 
ATOM   13    C CA  . ALA A 1 17  ? 27.402  18.647  -14.270  1.00 40.52  ? 10   ALA A CA  1 
ATOM   14    C C   . ALA A 1 17  ? 27.780  18.146  -12.868  1.00 36.54  ? 10   ALA A C   1 
ATOM   15    O O   . ALA A 1 17  ? 26.887  17.886  -12.076  1.00 39.86  ? 10   ALA A O   1 
ATOM   16    C CB  . ALA A 1 17  ? 27.440  17.534  -15.284  1.00 39.26  ? 10   ALA A CB  1 
ATOM   17    N N   . LEU A 1 18  ? 29.062  17.996  -12.575  1.00 34.91  ? 11   LEU A N   1 
ATOM   18    C CA  . LEU A 1 18  ? 29.536  17.477  -11.267  1.00 33.79  ? 11   LEU A CA  1 
ATOM   19    C C   . LEU A 1 18  ? 28.988  18.369  -10.144  1.00 34.09  ? 11   LEU A C   1 
ATOM   20    O O   . LEU A 1 18  ? 28.477  17.832  -9.154   1.00 29.17  ? 11   LEU A O   1 
ATOM   21    C CB  . LEU A 1 18  ? 31.066  17.455  -11.257  1.00 31.78  ? 11   LEU A CB  1 
ATOM   22    C CG  . LEU A 1 18  ? 31.680  16.909  -9.968   1.00 32.39  ? 11   LEU A CG  1 
ATOM   23    C CD1 . LEU A 1 18  ? 31.024  15.596  -9.571   1.00 33.09  ? 11   LEU A CD1 1 
ATOM   24    C CD2 . LEU A 1 18  ? 33.183  16.722  -10.093  1.00 31.93  ? 11   LEU A CD2 1 
ATOM   25    N N   . ALA A 1 19  ? 29.089  19.685  -10.328  1.00 37.86  ? 12   ALA A N   1 
ATOM   26    C CA  . ALA A 1 19  ? 28.629  20.739  -9.393   1.00 39.61  ? 12   ALA A CA  1 
ATOM   27    C C   . ALA A 1 19  ? 27.116  20.633  -9.159   1.00 40.51  ? 12   ALA A C   1 
ATOM   28    O O   . ALA A 1 19  ? 26.695  20.722  -7.991   1.00 47.03  ? 12   ALA A O   1 
ATOM   29    C CB  . ALA A 1 19  ? 29.000  22.091  -9.947   1.00 42.67  ? 12   ALA A CB  1 
ATOM   30    N N   . CYS A 1 20  ? 26.327  20.463  -10.222  1.00 39.80  ? 13   CYS A N   1 
ATOM   31    C CA  . CYS A 1 20  ? 24.851  20.328  -10.149  1.00 41.72  ? 13   CYS A CA  1 
ATOM   32    C C   . CYS A 1 20  ? 24.491  18.974  -9.525   1.00 38.70  ? 13   CYS A C   1 
ATOM   33    O O   . CYS A 1 20  ? 23.575  18.970  -8.678   1.00 40.51  ? 13   CYS A O   1 
ATOM   34    C CB  . CYS A 1 20  ? 24.187  20.494  -11.509  1.00 46.77  ? 13   CYS A CB  1 
ATOM   35    S SG  . CYS A 1 20  ? 24.443  22.137  -12.228  1.00 57.72  ? 13   CYS A SG  1 
ATOM   36    N N   . SER A 1 21  ? 25.188  17.880  -9.870   1.00 32.39  ? 14   SER A N   1 
ATOM   37    C CA  . SER A 1 21  ? 24.913  16.532  -9.297   1.00 30.28  ? 14   SER A CA  1 
ATOM   38    C C   . SER A 1 21  ? 25.202  16.552  -7.786   1.00 29.76  ? 14   SER A C   1 
ATOM   39    O O   . SER A 1 21  ? 24.476  15.888  -7.034   1.00 28.03  ? 14   SER A O   1 
ATOM   40    C CB  . SER A 1 21  ? 25.651  15.426  -10.010  1.00 28.03  ? 14   SER A CB  1 
ATOM   41    O OG  . SER A 1 21  ? 27.021  15.404  -9.656   1.00 31.07  ? 14   SER A OG  1 
ATOM   42    N N   . ALA A 1 22  ? 26.188  17.339  -7.365   1.00 28.93  ? 15   ALA A N   1 
ATOM   43    C CA  . ALA A 1 22  ? 26.592  17.531  -5.957   1.00 32.04  ? 15   ALA A CA  1 
ATOM   44    C C   . ALA A 1 22  ? 25.506  18.319  -5.216   1.00 34.89  ? 15   ALA A C   1 
ATOM   45    O O   . ALA A 1 22  ? 25.030  17.828  -4.176   1.00 30.91  ? 15   ALA A O   1 
ATOM   46    C CB  . ALA A 1 22  ? 27.931  18.230  -5.895   1.00 30.81  ? 15   ALA A CB  1 
ATOM   47    N N   . HIS A 1 23  ? 25.132  19.491  -5.743   1.00 38.89  ? 16   HIS A N   1 
ATOM   48    C CA  . HIS A 1 23  ? 24.122  20.397  -5.136   1.00 39.22  ? 16   HIS A CA  1 
ATOM   49    C C   . HIS A 1 23  ? 22.820  19.623  -4.899   1.00 35.37  ? 16   HIS A C   1 
ATOM   50    O O   . HIS A 1 23  ? 22.129  19.866  -3.892   1.00 35.93  ? 16   HIS A O   1 
ATOM   51    C CB  . HIS A 1 23  ? 23.929  21.625  -6.032   1.00 43.33  ? 16   HIS A CB  1 
ATOM   52    C CG  . HIS A 1 23  ? 22.817  22.493  -5.562   1.00 48.26  ? 16   HIS A CG  1 
ATOM   53    N ND1 . HIS A 1 23  ? 22.909  23.234  -4.403   1.00 52.05  ? 16   HIS A ND1 1 
ATOM   54    C CD2 . HIS A 1 23  ? 21.580  22.705  -6.061   1.00 51.29  ? 16   HIS A CD2 1 
ATOM   55    C CE1 . HIS A 1 23  ? 21.777  23.884  -4.220   1.00 56.72  ? 16   HIS A CE1 1 
ATOM   56    N NE2 . HIS A 1 23  ? 20.950  23.580  -5.225   1.00 55.50  ? 16   HIS A NE2 1 
ATOM   57    N N   . ALA A 1 24  ? 22.521  18.703  -5.805   1.00 34.92  ? 17   ALA A N   1 
ATOM   58    C CA  . ALA A 1 24  ? 21.263  17.929  -5.835   1.00 36.02  ? 17   ALA A CA  1 
ATOM   59    C C   . ALA A 1 24  ? 21.343  16.789  -4.828   1.00 34.95  ? 17   ALA A C   1 
ATOM   60    O O   . ALA A 1 24  ? 20.340  16.547  -4.159   1.00 35.64  ? 17   ALA A O   1 
ATOM   61    C CB  . ALA A 1 24  ? 20.990  17.403  -7.224   1.00 37.80  ? 17   ALA A CB  1 
ATOM   62    N N   . LEU A 1 25  ? 22.466  16.088  -4.734   1.00 34.47  ? 18   LEU A N   1 
ATOM   63    C CA  . LEU A 1 25  ? 22.616  15.026  -3.705   1.00 37.29  ? 18   LEU A CA  1 
ATOM   64    C C   . LEU A 1 25  ? 22.506  15.644  -2.303   1.00 38.00  ? 18   LEU A C   1 
ATOM   65    O O   . LEU A 1 25  ? 21.932  14.988  -1.424   1.00 34.51  ? 18   LEU A O   1 
ATOM   66    C CB  . LEU A 1 25  ? 23.953  14.305  -3.894   1.00 37.19  ? 18   LEU A CB  1 
ATOM   67    C CG  . LEU A 1 25  ? 24.072  13.469  -5.157   1.00 37.77  ? 18   LEU A CG  1 
ATOM   68    C CD1 . LEU A 1 25  ? 25.509  12.989  -5.309   1.00 39.85  ? 18   LEU A CD1 1 
ATOM   69    C CD2 . LEU A 1 25  ? 23.094  12.311  -5.146   1.00 35.89  ? 18   LEU A CD2 1 
ATOM   70    N N   A ASN A 1 26  ? 23.047  16.857  -2.118   0.48 40.01  ? 19   ASN A N   1 
ATOM   71    N N   B ASN A 1 26  ? 23.051  16.855  -2.121   0.52 42.22  ? 19   ASN A N   1 
ATOM   72    C CA  A ASN A 1 26  ? 22.945  17.681  -0.881   0.48 41.43  ? 19   ASN A CA  1 
ATOM   73    C CA  B ASN A 1 26  ? 22.946  17.675  -0.884   0.52 45.06  ? 19   ASN A CA  1 
ATOM   74    C C   A ASN A 1 26  ? 21.466  17.895  -0.563   0.48 40.97  ? 19   ASN A C   1 
ATOM   75    C C   B ASN A 1 26  ? 21.467  17.892  -0.564   0.52 42.98  ? 19   ASN A C   1 
ATOM   76    O O   A ASN A 1 26  ? 21.086  17.691  0.602    0.48 41.06  ? 19   ASN A O   1 
ATOM   77    O O   B ASN A 1 26  ? 21.085  17.691  0.604    0.52 43.00  ? 19   ASN A O   1 
ATOM   78    C CB  A ASN A 1 26  ? 23.675  19.026  -1.022   0.48 41.47  ? 19   ASN A CB  1 
ATOM   79    C CB  B ASN A 1 26  ? 23.659  19.029  -1.007   0.52 47.90  ? 19   ASN A CB  1 
ATOM   80    C CG  A ASN A 1 26  ? 23.520  19.972  0.154    0.48 40.80  ? 19   ASN A CG  1 
ATOM   81    C CG  B ASN A 1 26  ? 25.172  18.960  -0.922   0.52 50.65  ? 19   ASN A CG  1 
ATOM   82    O OD1 A ASN A 1 26  ? 22.918  21.038  0.028    0.48 40.78  ? 19   ASN A OD1 1 
ATOM   83    O OD1 B ASN A 1 26  ? 25.743  18.161  -0.180   0.52 54.69  ? 19   ASN A OD1 1 
ATOM   84    N ND2 A ASN A 1 26  ? 24.071  19.602  1.296    0.48 41.36  ? 19   ASN A ND2 1 
ATOM   85    N ND2 B ASN A 1 26  ? 25.837  19.832  -1.661   0.52 49.83  ? 19   ASN A ND2 1 
ATOM   86    N N   . LEU A 1 27  ? 20.677  18.267  -1.573   1.00 42.41  ? 20   LEU A N   1 
ATOM   87    C CA  . LEU A 1 27  ? 19.221  18.536  -1.430   1.00 41.77  ? 20   LEU A CA  1 
ATOM   88    C C   . LEU A 1 27  ? 18.464  17.243  -1.076   1.00 37.14  ? 20   LEU A C   1 
ATOM   89    O O   . LEU A 1 27  ? 17.561  17.319  -0.234   1.00 36.97  ? 20   LEU A O   1 
ATOM   90    C CB  . LEU A 1 27  ? 18.750  19.171  -2.746   1.00 48.19  ? 20   LEU A CB  1 
ATOM   91    C CG  . LEU A 1 27  ? 17.474  20.004  -2.759   1.00 55.00  ? 20   LEU A CG  1 
ATOM   92    C CD1 . LEU A 1 27  ? 16.265  19.113  -2.984   1.00 57.52  ? 20   LEU A CD1 1 
ATOM   93    C CD2 . LEU A 1 27  ? 17.326  20.852  -1.498   1.00 56.56  ? 20   LEU A CD2 1 
ATOM   94    N N   . ILE A 1 28  ? 18.847  16.097  -1.646   1.00 35.95  ? 21   ILE A N   1 
ATOM   95    C CA  . ILE A 1 28  ? 18.206  14.769  -1.384   1.00 34.84  ? 21   ILE A CA  1 
ATOM   96    C C   . ILE A 1 28  ? 18.366  14.389  0.095    1.00 35.93  ? 21   ILE A C   1 
ATOM   97    O O   . ILE A 1 28  ? 17.429  13.779  0.643    1.00 36.77  ? 21   ILE A O   1 
ATOM   98    C CB  . ILE A 1 28  ? 18.776  13.679  -2.321   1.00 32.92  ? 21   ILE A CB  1 
ATOM   99    C CG1 . ILE A 1 28  ? 18.363  13.934  -3.769   1.00 32.65  ? 21   ILE A CG1 1 
ATOM   100   C CG2 . ILE A 1 28  ? 18.388  12.277  -1.861   1.00 31.00  ? 21   ILE A CG2 1 
ATOM   101   C CD1 . ILE A 1 28  ? 19.074  13.082  -4.768   1.00 32.63  ? 21   ILE A CD1 1 
ATOM   102   N N   . GLU A 1 29  ? 19.501  14.718  0.715    1.00 38.03  ? 22   GLU A N   1 
ATOM   103   C CA  . GLU A 1 29  ? 19.810  14.373  2.131    1.00 41.45  ? 22   GLU A CA  1 
ATOM   104   C C   . GLU A 1 29  ? 18.988  15.230  3.091    1.00 42.12  ? 22   GLU A C   1 
ATOM   105   O O   . GLU A 1 29  ? 18.541  14.673  4.097    1.00 38.14  ? 22   GLU A O   1 
ATOM   106   C CB  . GLU A 1 29  ? 21.295  14.559  2.421    1.00 44.33  ? 22   GLU A CB  1 
ATOM   107   C CG  . GLU A 1 29  ? 22.136  13.581  1.616    1.00 46.56  ? 22   GLU A CG  1 
ATOM   108   C CD  . GLU A 1 29  ? 23.620  13.544  1.916    1.00 48.70  ? 22   GLU A CD  1 
ATOM   109   O OE1 . GLU A 1 29  ? 23.991  13.656  3.101    1.00 52.81  ? 22   GLU A OE1 1 
ATOM   110   O OE2 . GLU A 1 29  ? 24.384  13.406  0.949    1.00 49.05  ? 22   GLU A OE2 1 
ATOM   111   N N   . LYS A 1 30  ? 18.844  16.527  2.799    1.00 44.84  ? 23   LYS A N   1 
ATOM   112   C CA  . LYS A 1 30  ? 18.078  17.516  3.610    1.00 45.49  ? 23   LYS A CA  1 
ATOM   113   C C   . LYS A 1 30  ? 16.648  16.997  3.799    1.00 44.19  ? 23   LYS A C   1 
ATOM   114   O O   . LYS A 1 30  ? 16.073  16.506  2.830    1.00 41.55  ? 23   LYS A O   1 
ATOM   115   C CB  . LYS A 1 30  ? 18.115  18.895  2.936    1.00 47.10  ? 23   LYS A CB  1 
ATOM   116   C CG  . LYS A 1 30  ? 19.477  19.597  2.983    1.00 51.73  ? 23   LYS A CG  1 
ATOM   117   C CD  . LYS A 1 30  ? 19.594  20.946  2.235    1.00 53.03  ? 23   LYS A CD  1 
ATOM   118   C CE  . LYS A 1 30  ? 18.773  22.068  2.834    1.00 56.48  ? 23   LYS A CE  1 
ATOM   119   N NZ  . LYS A 1 30  ? 18.766  22.032  4.323    1.00 59.10  ? 23   LYS A NZ  1 
ATOM   120   N N   A ARG A 1 31  ? 16.122  17.079  5.026    0.50 45.10  ? 24   ARG A N   1 
ATOM   121   N N   B ARG A 1 31  ? 16.118  17.080  5.023    0.50 43.76  ? 24   ARG A N   1 
ATOM   122   C CA  A ARG A 1 31  ? 14.724  16.699  5.374    0.50 48.07  ? 24   ARG A CA  1 
ATOM   123   C CA  B ARG A 1 31  ? 14.714  16.707  5.358    0.50 45.79  ? 24   ARG A CA  1 
ATOM   124   C C   A ARG A 1 31  ? 13.874  17.968  5.548    0.50 47.75  ? 24   ARG A C   1 
ATOM   125   C C   B ARG A 1 31  ? 13.869  17.973  5.546    0.50 46.44  ? 24   ARG A C   1 
ATOM   126   O O   A ARG A 1 31  ? 12.640  17.871  5.494    0.50 46.95  ? 24   ARG A O   1 
ATOM   127   O O   B ARG A 1 31  ? 12.635  17.875  5.495    0.50 45.78  ? 24   ARG A O   1 
ATOM   128   C CB  A ARG A 1 31  ? 14.687  15.861  6.659    0.50 48.73  ? 24   ARG A CB  1 
ATOM   129   C CB  B ARG A 1 31  ? 14.668  15.847  6.625    0.50 44.69  ? 24   ARG A CB  1 
ATOM   130   C CG  A ARG A 1 31  ? 15.389  14.508  6.598    0.50 50.65  ? 24   ARG A CG  1 
ATOM   131   C CG  B ARG A 1 31  ? 15.150  14.419  6.415    0.50 44.97  ? 24   ARG A CG  1 
ATOM   132   C CD  A ARG A 1 31  ? 14.850  13.571  5.521    0.50 53.62  ? 24   ARG A CD  1 
ATOM   133   C CD  B ARG A 1 31  ? 14.352  13.662  5.357    0.50 45.77  ? 24   ARG A CD  1 
ATOM   134   N NE  A ARG A 1 31  ? 15.506  12.264  5.431    0.50 53.30  ? 24   ARG A NE  1 
ATOM   135   N NE  B ARG A 1 31  ? 12.889  13.686  5.460    0.50 42.38  ? 24   ARG A NE  1 
ATOM   136   C CZ  A ARG A 1 31  ? 16.275  11.860  4.420    0.50 49.85  ? 24   ARG A CZ  1 
ATOM   137   C CZ  B ARG A 1 31  ? 12.149  12.714  5.984    0.50 41.14  ? 24   ARG A CZ  1 
ATOM   138   N NH1 A ARG A 1 31  ? 16.517  12.661  3.401    0.50 48.88  ? 24   ARG A NH1 1 
ATOM   139   N NH1 B ARG A 1 31  ? 12.723  11.642  6.502    0.50 41.27  ? 24   ARG A NH1 1 
ATOM   140   N NH2 A ARG A 1 31  ? 16.808  10.655  4.431    0.50 48.53  ? 24   ARG A NH2 1 
ATOM   141   N NH2 B ARG A 1 31  ? 10.834  12.822  6.000    0.50 41.28  ? 24   ARG A NH2 1 
ATOM   142   N N   . THR A 1 32  ? 14.536  19.101  5.796    1.00 48.51  ? 25   THR A N   1 
ATOM   143   C CA  . THR A 1 32  ? 13.900  20.383  6.169    1.00 50.32  ? 25   THR A CA  1 
ATOM   144   C C   . THR A 1 32  ? 14.578  21.504  5.389    1.00 46.34  ? 25   THR A C   1 
ATOM   145   O O   . THR A 1 32  ? 15.728  21.343  4.964    1.00 43.64  ? 25   THR A O   1 
ATOM   146   C CB  . THR A 1 32  ? 14.008  20.643  7.679    1.00 53.12  ? 25   THR A CB  1 
ATOM   147   O OG1 . THR A 1 32  ? 15.374  20.590  8.090    1.00 50.82  ? 25   THR A OG1 1 
ATOM   148   C CG2 . THR A 1 32  ? 13.219  19.650  8.503    1.00 55.90  ? 25   THR A CG2 1 
ATOM   149   N N   . LEU A 1 33  ? 13.854  22.602  5.228    1.00 46.23  ? 26   LEU A N   1 
ATOM   150   C CA  . LEU A 1 33  ? 14.284  23.812  4.496    1.00 47.26  ? 26   LEU A CA  1 
ATOM   151   C C   . LEU A 1 33  ? 13.880  25.003  5.361    1.00 48.87  ? 26   LEU A C   1 
ATOM   152   O O   . LEU A 1 33  ? 12.683  25.080  5.691    1.00 47.32  ? 26   LEU A O   1 
ATOM   153   C CB  . LEU A 1 33  ? 13.557  23.841  3.146    1.00 47.76  ? 26   LEU A CB  1 
ATOM   154   C CG  . LEU A 1 33  ? 13.745  22.620  2.230    1.00 47.22  ? 26   LEU A CG  1 
ATOM   155   C CD1 . LEU A 1 33  ? 12.642  22.557  1.179    1.00 45.39  ? 26   LEU A CD1 1 
ATOM   156   C CD2 . LEU A 1 33  ? 15.111  22.670  1.568    1.00 46.45  ? 26   LEU A CD2 1 
ATOM   157   N N   . ASP A 1 34  ? 14.814  25.874  5.746    1.00 51.72  ? 27   ASP A N   1 
ATOM   158   C CA  . ASP A 1 34  ? 14.429  27.160  6.386    1.00 60.15  ? 27   ASP A CA  1 
ATOM   159   C C   . ASP A 1 34  ? 13.851  28.046  5.274    1.00 61.96  ? 27   ASP A C   1 
ATOM   160   O O   . ASP A 1 34  ? 13.942  27.641  4.090    1.00 54.86  ? 27   ASP A O   1 
ATOM   161   C CB  . ASP A 1 34  ? 15.578  27.793  7.186    1.00 65.76  ? 27   ASP A CB  1 
ATOM   162   C CG  . ASP A 1 34  ? 16.770  28.277  6.371    1.00 69.19  ? 27   ASP A CG  1 
ATOM   163   O OD1 . ASP A 1 34  ? 16.638  28.420  5.147    1.00 72.06  ? 27   ASP A OD1 1 
ATOM   164   O OD2 . ASP A 1 34  ? 17.824  28.508  6.971    1.00 82.95  ? 27   ASP A OD2 1 
ATOM   165   N N   . HIS A 1 35  ? 13.269  29.191  5.634    1.00 62.36  ? 28   HIS A N   1 
ATOM   166   C CA  . HIS A 1 35  ? 12.663  30.152  4.680    1.00 63.88  ? 28   HIS A CA  1 
ATOM   167   C C   . HIS A 1 35  ? 13.617  30.407  3.501    1.00 64.73  ? 28   HIS A C   1 
ATOM   168   O O   . HIS A 1 35  ? 13.137  30.440  2.355    1.00 65.29  ? 28   HIS A O   1 
ATOM   169   C CB  . HIS A 1 35  ? 12.268  31.443  5.400    1.00 62.60  ? 28   HIS A CB  1 
ATOM   170   C CG  . HIS A 1 35  ? 11.406  32.322  4.565    1.00 68.43  ? 28   HIS A CG  1 
ATOM   171   N ND1 . HIS A 1 35  ? 10.072  32.025  4.317    1.00 74.80  ? 28   HIS A ND1 1 
ATOM   172   C CD2 . HIS A 1 35  ? 11.679  33.464  3.897    1.00 72.02  ? 28   HIS A CD2 1 
ATOM   173   C CE1 . HIS A 1 35  ? 9.558   32.959  3.541    1.00 78.74  ? 28   HIS A CE1 1 
ATOM   174   N NE2 . HIS A 1 35  ? 10.527  33.857  3.269    1.00 79.53  ? 28   HIS A NE2 1 
ATOM   175   N N   . GLU A 1 36  ? 14.918  30.560  3.765    1.00 65.31  ? 29   GLU A N   1 
ATOM   176   C CA  . GLU A 1 36  ? 15.930  30.956  2.745    1.00 68.78  ? 29   GLU A CA  1 
ATOM   177   C C   . GLU A 1 36  ? 16.225  29.780  1.804    1.00 63.98  ? 29   GLU A C   1 
ATOM   178   O O   . GLU A 1 36  ? 16.346  30.022  0.589    1.00 54.81  ? 29   GLU A O   1 
ATOM   179   C CB  . GLU A 1 36  ? 17.206  31.491  3.404    1.00 72.91  ? 29   GLU A CB  1 
ATOM   180   C CG  . GLU A 1 36  ? 17.049  32.902  3.949    1.00 78.83  ? 29   GLU A CG  1 
ATOM   181   C CD  . GLU A 1 36  ? 16.257  33.838  3.040    1.00 85.63  ? 29   GLU A CD  1 
ATOM   182   O OE1 . GLU A 1 36  ? 16.696  34.068  1.896    1.00 87.20  ? 29   GLU A OE1 1 
ATOM   183   O OE2 . GLU A 1 36  ? 15.176  34.309  3.456    1.00 85.79  ? 29   GLU A OE2 1 
ATOM   184   N N   . GLU A 1 37  ? 16.353  28.562  2.330    1.00 60.03  ? 30   GLU A N   1 
ATOM   185   C CA  . GLU A 1 37  ? 16.652  27.361  1.507    1.00 58.12  ? 30   GLU A CA  1 
ATOM   186   C C   . GLU A 1 37  ? 15.452  27.084  0.609    1.00 58.20  ? 30   GLU A C   1 
ATOM   187   O O   . GLU A 1 37  ? 15.676  26.786  -0.569   1.00 63.00  ? 30   GLU A O   1 
ATOM   188   C CB  . GLU A 1 37  ? 16.953  26.146  2.381    1.00 58.02  ? 30   GLU A CB  1 
ATOM   189   C CG  . GLU A 1 37  ? 18.274  26.271  3.108    1.00 60.01  ? 30   GLU A CG  1 
ATOM   190   C CD  . GLU A 1 37  ? 18.441  25.345  4.293    1.00 60.74  ? 30   GLU A CD  1 
ATOM   191   O OE1 . GLU A 1 37  ? 17.432  25.090  5.008    1.00 64.42  ? 30   GLU A OE1 1 
ATOM   192   O OE2 . GLU A 1 37  ? 19.574  24.857  4.479    1.00 55.65  ? 30   GLU A OE2 1 
ATOM   193   N N   . MET A 1 38  ? 14.243  27.187  1.168    1.00 55.00  ? 31   MET A N   1 
ATOM   194   C CA  . MET A 1 38  ? 12.947  27.019  0.460    1.00 55.94  ? 31   MET A CA  1 
ATOM   195   C C   . MET A 1 38  ? 12.864  28.041  -0.680   1.00 52.77  ? 31   MET A C   1 
ATOM   196   O O   . MET A 1 38  ? 12.575  27.621  -1.811   1.00 47.46  ? 31   MET A O   1 
ATOM   197   C CB  . MET A 1 38  ? 11.763  27.213  1.421    1.00 57.06  ? 31   MET A CB  1 
ATOM   198   C CG  . MET A 1 38  ? 10.391  27.156  0.766    1.00 58.83  ? 31   MET A CG  1 
ATOM   199   S SD  . MET A 1 38  ? 9.746   28.789  0.261    1.00 66.06  ? 31   MET A SD  1 
ATOM   200   C CE  . MET A 1 38  ? 9.455   29.539  1.864    1.00 68.42  ? 31   MET A CE  1 
ATOM   201   N N   . LYS A 1 39  ? 13.092  29.326  -0.388   1.00 51.52  ? 32   LYS A N   1 
ATOM   202   C CA  . LYS A 1 39  ? 12.933  30.420  -1.382   1.00 53.91  ? 32   LYS A CA  1 
ATOM   203   C C   . LYS A 1 39  ? 13.907  30.183  -2.534   1.00 48.84  ? 32   LYS A C   1 
ATOM   204   O O   . LYS A 1 39  ? 13.514  30.394  -3.686   1.00 47.74  ? 32   LYS A O   1 
ATOM   205   C CB  . LYS A 1 39  ? 13.147  31.808  -0.773   1.00 59.50  ? 32   LYS A CB  1 
ATOM   206   C CG  . LYS A 1 39  ? 11.892  32.673  -0.703   1.00 65.34  ? 32   LYS A CG  1 
ATOM   207   C CD  . LYS A 1 39  ? 11.989  33.840  0.262    1.00 73.49  ? 32   LYS A CD  1 
ATOM   208   C CE  . LYS A 1 39  ? 13.128  34.799  -0.040   1.00 81.51  ? 32   LYS A CE  1 
ATOM   209   N NZ  . LYS A 1 39  ? 13.686  35.409  1.193    1.00 87.58  ? 32   LYS A NZ  1 
ATOM   210   N N   . ALA A 1 40  ? 15.121  29.740  -2.220   1.00 44.96  ? 33   ALA A N   1 
ATOM   211   C CA  . ALA A 1 40  ? 16.200  29.490  -3.202   1.00 43.99  ? 33   ALA A CA  1 
ATOM   212   C C   . ALA A 1 40  ? 15.848  28.277  -4.069   1.00 44.47  ? 33   ALA A C   1 
ATOM   213   O O   . ALA A 1 40  ? 16.103  28.336  -5.283   1.00 43.56  ? 33   ALA A O   1 
ATOM   214   C CB  . ALA A 1 40  ? 17.513  29.296  -2.493   1.00 44.21  ? 33   ALA A CB  1 
ATOM   215   N N   . LEU A 1 41  ? 15.291  27.217  -3.473   1.00 44.48  ? 34   LEU A N   1 
ATOM   216   C CA  . LEU A 1 41  ? 14.968  25.949  -4.191   1.00 42.38  ? 34   LEU A CA  1 
ATOM   217   C C   . LEU A 1 41  ? 13.744  26.167  -5.077   1.00 41.54  ? 34   LEU A C   1 
ATOM   218   O O   . LEU A 1 41  ? 13.765  25.730  -6.227   1.00 43.17  ? 34   LEU A O   1 
ATOM   219   C CB  . LEU A 1 41  ? 14.710  24.819  -3.191   1.00 41.13  ? 34   LEU A CB  1 
ATOM   220   C CG  . LEU A 1 41  ? 14.135  23.536  -3.785   1.00 40.00  ? 34   LEU A CG  1 
ATOM   221   C CD1 . LEU A 1 41  ? 15.142  22.874  -4.705   1.00 39.75  ? 34   LEU A CD1 1 
ATOM   222   C CD2 . LEU A 1 41  ? 13.700  22.582  -2.682   1.00 42.45  ? 34   LEU A CD2 1 
ATOM   223   N N   . ASN A 1 42  ? 12.706  26.810  -4.556   1.00 43.59  ? 35   ASN A N   1 
ATOM   224   C CA  . ASN A 1 42  ? 11.497  27.143  -5.350   1.00 45.50  ? 35   ASN A CA  1 
ATOM   225   C C   . ASN A 1 42  ? 11.947  27.922  -6.596   1.00 44.45  ? 35   ASN A C   1 
ATOM   226   O O   . ASN A 1 42  ? 11.566  27.523  -7.713   1.00 42.97  ? 35   ASN A O   1 
ATOM   227   C CB  . ASN A 1 42  ? 10.450  27.869  -4.499   1.00 46.20  ? 35   ASN A CB  1 
ATOM   228   C CG  . ASN A 1 42  ? 9.651   26.932  -3.611   1.00 46.56  ? 35   ASN A CG  1 
ATOM   229   O OD1 . ASN A 1 42  ? 10.131  25.880  -3.182   1.00 39.77  ? 35   ASN A OD1 1 
ATOM   230   N ND2 . ASN A 1 42  ? 8.403   27.294  -3.354   1.00 53.25  ? 35   ASN A ND2 1 
ATOM   231   N N   . ARG A 1 43  ? 12.761  28.958  -6.404   1.00 46.36  ? 36   ARG A N   1 
ATOM   232   C CA  . ARG A 1 43  ? 13.248  29.857  -7.480   1.00 52.07  ? 36   ARG A CA  1 
ATOM   233   C C   . ARG A 1 43  ? 14.045  29.033  -8.510   1.00 49.29  ? 36   ARG A C   1 
ATOM   234   O O   . ARG A 1 43  ? 13.872  29.263  -9.722   1.00 45.83  ? 36   ARG A O   1 
ATOM   235   C CB  . ARG A 1 43  ? 14.047  31.001  -6.850   1.00 59.58  ? 36   ARG A CB  1 
ATOM   236   C CG  . ARG A 1 43  ? 14.509  32.063  -7.839   1.00 70.78  ? 36   ARG A CG  1 
ATOM   237   C CD  . ARG A 1 43  ? 14.969  33.358  -7.176   1.00 78.28  ? 36   ARG A CD  1 
ATOM   238   N NE  . ARG A 1 43  ? 16.018  33.159  -6.168   1.00 85.41  ? 36   ARG A NE  1 
ATOM   239   C CZ  . ARG A 1 43  ? 15.883  33.312  -4.838   1.00 88.65  ? 36   ARG A CZ  1 
ATOM   240   N NH1 . ARG A 1 43  ? 14.734  33.701  -4.301   1.00 87.62  ? 36   ARG A NH1 1 
ATOM   241   N NH2 . ARG A 1 43  ? 16.923  33.086  -4.053   1.00 81.40  ? 36   ARG A NH2 1 
ATOM   242   N N   . GLU A 1 44  ? 14.857  28.076  -8.055   1.00 43.93  ? 37   GLU A N   1 
ATOM   243   C CA  . GLU A 1 44  ? 15.652  27.166  -8.930   1.00 40.42  ? 37   GLU A CA  1 
ATOM   244   C C   . GLU A 1 44  ? 14.706  26.279  -9.744   1.00 38.60  ? 37   GLU A C   1 
ATOM   245   O O   . GLU A 1 44  ? 14.883  26.202  -10.965  1.00 37.18  ? 37   GLU A O   1 
ATOM   246   C CB  . GLU A 1 44  ? 16.594  26.255  -8.137   1.00 38.41  ? 37   GLU A CB  1 
ATOM   247   C CG  . GLU A 1 44  ? 18.044  26.663  -8.214   1.00 40.50  ? 37   GLU A CG  1 
ATOM   248   C CD  . GLU A 1 44  ? 18.964  25.825  -7.341   1.00 43.28  ? 37   GLU A CD  1 
ATOM   249   O OE1 . GLU A 1 44  ? 18.637  25.620  -6.140   1.00 41.06  ? 37   GLU A OE1 1 
ATOM   250   O OE2 . GLU A 1 44  ? 20.006  25.374  -7.863   1.00 47.33  ? 37   GLU A OE2 1 
ATOM   251   N N   . VAL A 1 45  ? 13.769  25.601  -9.082   1.00 36.40  ? 38   VAL A N   1 
ATOM   252   C CA  . VAL A 1 45  ? 12.900  24.575  -9.724   1.00 36.72  ? 38   VAL A CA  1 
ATOM   253   C C   . VAL A 1 45  ? 12.088  25.256  -10.837  1.00 40.48  ? 38   VAL A C   1 
ATOM   254   O O   . VAL A 1 45  ? 11.957  24.657  -11.911  1.00 42.59  ? 38   VAL A O   1 
ATOM   255   C CB  . VAL A 1 45  ? 12.024  23.837  -8.694   1.00 34.99  ? 38   VAL A CB  1 
ATOM   256   C CG1 . VAL A 1 45  ? 10.942  22.996  -9.354   1.00 34.45  ? 38   VAL A CG1 1 
ATOM   257   C CG2 . VAL A 1 45  ? 12.862  22.955  -7.788   1.00 35.66  ? 38   VAL A CG2 1 
ATOM   258   N N   . ILE A 1 46  ? 11.608  26.482  -10.624  1.00 43.15  ? 39   ILE A N   1 
ATOM   259   C CA  . ILE A 1 46  ? 10.801  27.228  -11.634  1.00 44.17  ? 39   ILE A CA  1 
ATOM   260   C C   . ILE A 1 46  ? 11.705  27.591  -12.817  1.00 43.02  ? 39   ILE A C   1 
ATOM   261   O O   . ILE A 1 46  ? 11.291  27.350  -13.948  1.00 43.74  ? 39   ILE A O   1 
ATOM   262   C CB  . ILE A 1 46  ? 10.138  28.471  -11.015  1.00 48.19  ? 39   ILE A CB  1 
ATOM   263   C CG1 . ILE A 1 46  ? 9.078   28.095  -9.980   1.00 51.63  ? 39   ILE A CG1 1 
ATOM   264   C CG2 . ILE A 1 46  ? 9.554   29.368  -12.102  1.00 49.31  ? 39   ILE A CG2 1 
ATOM   265   C CD1 . ILE A 1 46  ? 8.580   29.271  -9.170   1.00 52.55  ? 39   ILE A CD1 1 
ATOM   266   N N   . GLU A 1 47  ? 12.887  28.149  -12.553  1.00 43.16  ? 40   GLU A N   1 
ATOM   267   C CA  . GLU A 1 47  ? 13.893  28.481  -13.593  1.00 43.15  ? 40   GLU A CA  1 
ATOM   268   C C   . GLU A 1 47  ? 14.221  27.215  -14.397  1.00 39.60  ? 40   GLU A C   1 
ATOM   269   O O   . GLU A 1 47  ? 14.187  27.292  -15.636  1.00 38.39  ? 40   GLU A O   1 
ATOM   270   C CB  . GLU A 1 47  ? 15.133  29.112  -12.950  1.00 48.13  ? 40   GLU A CB  1 
ATOM   271   C CG  . GLU A 1 47  ? 16.315  29.329  -13.895  1.00 54.00  ? 40   GLU A CG  1 
ATOM   272   C CD  . GLU A 1 47  ? 16.110  30.363  -15.000  1.00 63.49  ? 40   GLU A CD  1 
ATOM   273   O OE1 . GLU A 1 47  ? 15.058  31.047  -15.009  1.00 68.41  ? 40   GLU A OE1 1 
ATOM   274   O OE2 . GLU A 1 47  ? 17.010  30.495  -15.861  1.00 77.60  ? 40   GLU A OE2 1 
ATOM   275   N N   . TYR A 1 48  ? 14.480  26.082  -13.737  1.00 36.51  ? 41   TYR A N   1 
ATOM   276   C CA  . TYR A 1 48  ? 14.899  24.819  -14.404  1.00 36.57  ? 41   TYR A CA  1 
ATOM   277   C C   . TYR A 1 48  ? 13.727  24.164  -15.155  1.00 36.46  ? 41   TYR A C   1 
ATOM   278   O O   . TYR A 1 48  ? 13.988  23.551  -16.211  1.00 36.60  ? 41   TYR A O   1 
ATOM   279   C CB  . TYR A 1 48  ? 15.552  23.840  -13.420  1.00 35.32  ? 41   TYR A CB  1 
ATOM   280   C CG  . TYR A 1 48  ? 16.825  24.330  -12.782  1.00 37.83  ? 41   TYR A CG  1 
ATOM   281   C CD1 . TYR A 1 48  ? 17.497  25.457  -13.244  1.00 38.83  ? 41   TYR A CD1 1 
ATOM   282   C CD2 . TYR A 1 48  ? 17.372  23.651  -11.705  1.00 39.66  ? 41   TYR A CD2 1 
ATOM   283   C CE1 . TYR A 1 48  ? 18.665  25.898  -12.641  1.00 39.71  ? 41   TYR A CE1 1 
ATOM   284   C CE2 . TYR A 1 48  ? 18.539  24.082  -11.091  1.00 40.54  ? 41   TYR A CE2 1 
ATOM   285   C CZ  . TYR A 1 48  ? 19.195  25.204  -11.567  1.00 41.08  ? 41   TYR A CZ  1 
ATOM   286   O OH  . TYR A 1 48  ? 20.343  25.628  -10.955  1.00 43.76  ? 41   TYR A OH  1 
ATOM   287   N N   . PHE A 1 49  ? 12.487  24.251  -14.666  1.00 36.10  ? 42   PHE A N   1 
ATOM   288   C CA  . PHE A 1 49  ? 11.308  23.724  -15.410  1.00 36.16  ? 42   PHE A CA  1 
ATOM   289   C C   . PHE A 1 49  ? 11.218  24.481  -16.735  1.00 38.34  ? 42   PHE A C   1 
ATOM   290   O O   . PHE A 1 49  ? 11.060  23.847  -17.782  1.00 38.16  ? 42   PHE A O   1 
ATOM   291   C CB  . PHE A 1 49  ? 10.015  23.813  -14.591  1.00 34.61  ? 42   PHE A CB  1 
ATOM   292   C CG  . PHE A 1 49  ? 9.544   22.480  -14.066  1.00 33.79  ? 42   PHE A CG  1 
ATOM   293   C CD1 . PHE A 1 49  ? 10.065  21.941  -12.897  1.00 34.72  ? 42   PHE A CD1 1 
ATOM   294   C CD2 . PHE A 1 49  ? 8.597   21.745  -14.757  1.00 36.97  ? 42   PHE A CD2 1 
ATOM   295   C CE1 . PHE A 1 49  ? 9.655   20.701  -12.430  1.00 34.21  ? 42   PHE A CE1 1 
ATOM   296   C CE2 . PHE A 1 49  ? 8.168   20.514  -14.279  1.00 37.96  ? 42   PHE A CE2 1 
ATOM   297   C CZ  . PHE A 1 49  ? 8.703   19.991  -13.120  1.00 36.31  ? 42   PHE A CZ  1 
ATOM   298   N N   . LYS A 1 50  ? 11.378  25.800  -16.651  1.00 43.57  ? 43   LYS A N   1 
ATOM   299   C CA  . LYS A 1 50  ? 11.331  26.776  -17.766  1.00 49.03  ? 43   LYS A CA  1 
ATOM   300   C C   . LYS A 1 50  ? 12.460  26.498  -18.769  1.00 44.76  ? 43   LYS A C   1 
ATOM   301   O O   . LYS A 1 50  ? 12.188  26.558  -19.986  1.00 48.38  ? 43   LYS A O   1 
ATOM   302   C CB  . LYS A 1 50  ? 11.412  28.181  -17.161  1.00 57.26  ? 43   LYS A CB  1 
ATOM   303   C CG  . LYS A 1 50  ? 11.473  29.332  -18.150  1.00 65.43  ? 43   LYS A CG  1 
ATOM   304   C CD  . LYS A 1 50  ? 11.213  30.679  -17.503  1.00 72.06  ? 43   LYS A CD  1 
ATOM   305   C CE  . LYS A 1 50  ? 11.845  31.827  -18.263  1.00 73.19  ? 43   LYS A CE  1 
ATOM   306   N NZ  . LYS A 1 50  ? 13.316  31.872  -18.076  1.00 72.32  ? 43   LYS A NZ  1 
ATOM   307   N N   . GLU A 1 51  ? 13.667  26.193  -18.300  1.00 39.78  ? 44   GLU A N   1 
ATOM   308   C CA  . GLU A 1 51  ? 14.872  26.137  -19.168  1.00 39.51  ? 44   GLU A CA  1 
ATOM   309   C C   . GLU A 1 51  ? 15.190  24.706  -19.620  1.00 37.75  ? 44   GLU A C   1 
ATOM   310   O O   . GLU A 1 51  ? 15.974  24.592  -20.583  1.00 40.62  ? 44   GLU A O   1 
ATOM   311   C CB  . GLU A 1 51  ? 16.099  26.725  -18.462  1.00 41.39  ? 44   GLU A CB  1 
ATOM   312   C CG  . GLU A 1 51  ? 16.041  28.236  -18.301  1.00 44.25  ? 44   GLU A CG  1 
ATOM   313   C CD  . GLU A 1 51  ? 15.864  29.008  -19.597  1.00 49.35  ? 44   GLU A CD  1 
ATOM   314   O OE1 . GLU A 1 51  ? 16.569  28.697  -20.580  1.00 51.42  ? 44   GLU A OE1 1 
ATOM   315   O OE2 . GLU A 1 51  ? 15.009  29.906  -19.625  1.00 56.81  ? 44   GLU A OE2 1 
ATOM   316   N N   . HIS A 1 52  ? 14.644  23.658  -18.988  1.00 34.14  ? 45   HIS A N   1 
ATOM   317   C CA  . HIS A 1 52  ? 15.137  22.267  -19.213  1.00 32.67  ? 45   HIS A CA  1 
ATOM   318   C C   . HIS A 1 52  ? 14.064  21.175  -19.196  1.00 32.56  ? 45   HIS A C   1 
ATOM   319   O O   . HIS A 1 52  ? 14.423  20.032  -19.544  1.00 30.95  ? 45   HIS A O   1 
ATOM   320   C CB  . HIS A 1 52  ? 16.222  21.946  -18.187  1.00 32.55  ? 45   HIS A CB  1 
ATOM   321   C CG  . HIS A 1 52  ? 17.385  22.865  -18.286  1.00 31.36  ? 45   HIS A CG  1 
ATOM   322   N ND1 . HIS A 1 52  ? 18.143  22.956  -19.428  1.00 30.72  ? 45   HIS A ND1 1 
ATOM   323   C CD2 . HIS A 1 52  ? 17.915  23.736  -17.405  1.00 32.21  ? 45   HIS A CD2 1 
ATOM   324   C CE1 . HIS A 1 52  ? 19.109  23.828  -19.244  1.00 32.16  ? 45   HIS A CE1 1 
ATOM   325   N NE2 . HIS A 1 52  ? 18.999  24.321  -18.010  1.00 32.52  ? 45   HIS A NE2 1 
ATOM   326   N N   . VAL A 1 53  ? 12.824  21.476  -18.804  1.00 33.64  ? 46   VAL A N   1 
ATOM   327   C CA  . VAL A 1 53  ? 11.747  20.447  -18.675  1.00 34.04  ? 46   VAL A CA  1 
ATOM   328   C C   . VAL A 1 53  ? 10.603  20.806  -19.625  1.00 33.58  ? 46   VAL A C   1 
ATOM   329   O O   . VAL A 1 53  ? 10.387  20.049  -20.584  1.00 34.33  ? 46   VAL A O   1 
ATOM   330   C CB  . VAL A 1 53  ? 11.238  20.304  -17.228  1.00 34.84  ? 46   VAL A CB  1 
ATOM   331   C CG1 . VAL A 1 53  ? 10.266  19.136  -17.100  1.00 34.41  ? 46   VAL A CG1 1 
ATOM   332   C CG2 . VAL A 1 53  ? 12.391  20.173  -16.237  1.00 35.96  ? 46   VAL A CG2 1 
ATOM   333   N N   . ASN A 1 54  ? 9.903   21.908  -19.356  1.00 31.87  ? 47   ASN A N   1 
ATOM   334   C CA  . ASN A 1 54  ? 8.762   22.369  -20.180  1.00 32.55  ? 47   ASN A CA  1 
ATOM   335   C C   . ASN A 1 54  ? 8.185   23.655  -19.602  1.00 32.83  ? 47   ASN A C   1 
ATOM   336   O O   . ASN A 1 54  ? 7.468   23.600  -18.620  1.00 30.51  ? 47   ASN A O   1 
ATOM   337   C CB  . ASN A 1 54  ? 7.671   21.298  -20.261  1.00 32.83  ? 47   ASN A CB  1 
ATOM   338   C CG  . ASN A 1 54  ? 6.777   21.487  -21.465  1.00 32.97  ? 47   ASN A CG  1 
ATOM   339   O OD1 . ASN A 1 54  ? 6.379   22.606  -21.758  1.00 34.63  ? 47   ASN A OD1 1 
ATOM   340   N ND2 . ASN A 1 54  ? 6.485   20.417  -22.189  1.00 32.10  ? 47   ASN A ND2 1 
ATOM   341   N N   . PRO A 1 55  ? 8.405   24.847  -20.202  1.00 35.81  ? 48   PRO A N   1 
ATOM   342   C CA  . PRO A 1 55  ? 7.774   26.074  -19.708  1.00 36.75  ? 48   PRO A CA  1 
ATOM   343   C C   . PRO A 1 55  ? 6.240   26.024  -19.819  1.00 37.19  ? 48   PRO A C   1 
ATOM   344   O O   . PRO A 1 55  ? 5.571   26.819  -19.176  1.00 39.28  ? 48   PRO A O   1 
ATOM   345   C CB  . PRO A 1 55  ? 8.344   27.156  -20.636  1.00 35.84  ? 48   PRO A CB  1 
ATOM   346   C CG  . PRO A 1 55  ? 8.650   26.401  -21.905  1.00 36.51  ? 48   PRO A CG  1 
ATOM   347   C CD  . PRO A 1 55  ? 9.209   25.082  -21.409  1.00 36.72  ? 48   PRO A CD  1 
ATOM   348   N N   . GLY A 1 56  ? 5.728   25.103  -20.638  1.00 35.19  ? 49   GLY A N   1 
ATOM   349   C CA  . GLY A 1 56  ? 4.291   24.808  -20.787  1.00 37.53  ? 49   GLY A CA  1 
ATOM   350   C C   . GLY A 1 56  ? 3.657   24.313  -19.497  1.00 36.31  ? 49   GLY A C   1 
ATOM   351   O O   . GLY A 1 56  ? 2.514   24.711  -19.227  1.00 37.97  ? 49   GLY A O   1 
ATOM   352   N N   . PHE A 1 57  ? 4.349   23.461  -18.732  1.00 37.28  ? 50   PHE A N   1 
ATOM   353   C CA  . PHE A 1 57  ? 3.841   22.914  -17.450  1.00 39.11  ? 50   PHE A CA  1 
ATOM   354   C C   . PHE A 1 57  ? 3.597   24.091  -16.490  1.00 40.53  ? 50   PHE A C   1 
ATOM   355   O O   . PHE A 1 57  ? 2.595   24.043  -15.767  1.00 46.15  ? 50   PHE A O   1 
ATOM   356   C CB  . PHE A 1 57  ? 4.742   21.797  -16.909  1.00 40.45  ? 50   PHE A CB  1 
ATOM   357   C CG  . PHE A 1 57  ? 4.004   20.843  -16.008  1.00 44.69  ? 50   PHE A CG  1 
ATOM   358   C CD1 . PHE A 1 57  ? 3.119   19.919  -16.540  1.00 45.99  ? 50   PHE A CD1 1 
ATOM   359   C CD2 . PHE A 1 57  ? 4.138   20.900  -14.623  1.00 50.13  ? 50   PHE A CD2 1 
ATOM   360   C CE1 . PHE A 1 57  ? 2.397   19.068  -15.709  1.00 49.64  ? 50   PHE A CE1 1 
ATOM   361   C CE2 . PHE A 1 57  ? 3.417   20.047  -13.791  1.00 48.73  ? 50   PHE A CE2 1 
ATOM   362   C CZ  . PHE A 1 57  ? 2.546   19.129  -14.335  1.00 47.72  ? 50   PHE A CZ  1 
ATOM   363   N N   . LEU A 1 58  ? 4.414   25.147  -16.530  1.00 40.56  ? 51   LEU A N   1 
ATOM   364   C CA  . LEU A 1 58  ? 4.258   26.336  -15.650  1.00 42.99  ? 51   LEU A CA  1 
ATOM   365   C C   . LEU A 1 58  ? 3.021   27.149  -16.060  1.00 44.66  ? 51   LEU A C   1 
ATOM   366   O O   . LEU A 1 58  ? 2.362   27.747  -15.156  1.00 44.17  ? 51   LEU A O   1 
ATOM   367   C CB  . LEU A 1 58  ? 5.520   27.198  -15.705  1.00 41.37  ? 51   LEU A CB  1 
ATOM   368   C CG  . LEU A 1 58  ? 6.792   26.537  -15.184  1.00 41.08  ? 51   LEU A CG  1 
ATOM   369   C CD1 . LEU A 1 58  ? 7.997   27.418  -15.458  1.00 44.94  ? 51   LEU A CD1 1 
ATOM   370   C CD2 . LEU A 1 58  ? 6.703   26.233  -13.700  1.00 43.63  ? 51   LEU A CD2 1 
ATOM   371   N N   . GLU A 1 59  ? 2.705   27.196  -17.354  1.00 46.13  ? 52   GLU A N   1 
ATOM   372   C CA  . GLU A 1 59  ? 1.510   27.921  -17.863  1.00 54.38  ? 52   GLU A CA  1 
ATOM   373   C C   . GLU A 1 59  ? 0.244   27.173  -17.444  1.00 50.00  ? 52   GLU A C   1 
ATOM   374   O O   . GLU A 1 59  ? -0.705  27.860  -17.055  1.00 52.84  ? 52   GLU A O   1 
ATOM   375   C CB  . GLU A 1 59  ? 1.559   28.101  -19.385  1.00 65.91  ? 52   GLU A CB  1 
ATOM   376   C CG  . GLU A 1 59  ? 2.611   29.104  -19.844  1.00 73.98  ? 52   GLU A CG  1 
ATOM   377   C CD  . GLU A 1 59  ? 2.456   30.487  -19.224  1.00 80.79  ? 52   GLU A CD  1 
ATOM   378   O OE1 . GLU A 1 59  ? 1.424   31.141  -19.497  1.00 86.46  ? 52   GLU A OE1 1 
ATOM   379   O OE2 . GLU A 1 59  ? 3.345   30.897  -18.442  1.00 78.33  ? 52   GLU A OE2 1 
ATOM   380   N N   . TYR A 1 60  ? 0.227   25.837  -17.554  1.00 52.14  ? 53   TYR A N   1 
ATOM   381   C CA  . TYR A 1 60  ? -0.936  24.970  -17.215  1.00 56.45  ? 53   TYR A CA  1 
ATOM   382   C C   . TYR A 1 60  ? -1.283  25.120  -15.729  1.00 58.01  ? 53   TYR A C   1 
ATOM   383   O O   . TYR A 1 60  ? -2.458  25.365  -15.409  1.00 53.57  ? 53   TYR A O   1 
ATOM   384   C CB  . TYR A 1 60  ? -0.683  23.482  -17.476  1.00 59.04  ? 53   TYR A CB  1 
ATOM   385   C CG  . TYR A 1 60  ? -1.509  22.554  -16.605  1.00 67.82  ? 53   TYR A CG  1 
ATOM   386   C CD1 . TYR A 1 60  ? -2.867  22.345  -16.849  1.00 68.56  ? 53   TYR A CD1 1 
ATOM   387   C CD2 . TYR A 1 60  ? -0.947  21.884  -15.523  1.00 69.62  ? 53   TYR A CD2 1 
ATOM   388   C CE1 . TYR A 1 60  ? -3.629  21.480  -16.075  1.00 67.14  ? 53   TYR A CE1 1 
ATOM   389   C CE2 . TYR A 1 60  ? -1.703  21.032  -14.724  1.00 67.52  ? 53   TYR A CE2 1 
ATOM   390   C CZ  . TYR A 1 60  ? -3.047  20.826  -14.999  1.00 69.62  ? 53   TYR A CZ  1 
ATOM   391   O OH  . TYR A 1 60  ? -3.792  19.981  -14.221  1.00 69.67  ? 53   TYR A OH  1 
ATOM   392   N N   . ARG A 1 61  ? -0.286  24.937  -14.862  1.00 56.56  ? 54   ARG A N   1 
ATOM   393   C CA  . ARG A 1 61  ? -0.437  24.976  -13.382  1.00 57.57  ? 54   ARG A CA  1 
ATOM   394   C C   . ARG A 1 61  ? -0.973  26.351  -12.933  1.00 58.46  ? 54   ARG A C   1 
ATOM   395   O O   . ARG A 1 61  ? -1.690  26.382  -11.921  1.00 52.01  ? 54   ARG A O   1 
ATOM   396   C CB  . ARG A 1 61  ? 0.888   24.584  -12.725  1.00 58.73  ? 54   ARG A CB  1 
ATOM   397   C CG  . ARG A 1 61  ? 1.161   23.088  -12.738  1.00 59.16  ? 54   ARG A CG  1 
ATOM   398   C CD  . ARG A 1 61  ? 0.306   22.341  -11.736  1.00 61.31  ? 54   ARG A CD  1 
ATOM   399   N NE  . ARG A 1 61  ? 0.429   22.899  -10.396  1.00 59.87  ? 54   ARG A NE  1 
ATOM   400   C CZ  . ARG A 1 61  ? -0.586  23.257  -9.609   1.00 57.78  ? 54   ARG A CZ  1 
ATOM   401   N NH1 . ARG A 1 61  ? -1.844  23.144  -10.015  1.00 55.18  ? 54   ARG A NH1 1 
ATOM   402   N NH2 . ARG A 1 61  ? -0.331  23.757  -8.411   1.00 59.63  ? 54   ARG A NH2 1 
ATOM   403   N N   . LYS A 1 62  ? -0.708  27.426  -13.693  1.00 63.97  ? 55   LYS A N   1 
ATOM   404   C CA  . LYS A 1 62  ? -1.240  28.807  -13.456  1.00 65.07  ? 55   LYS A CA  1 
ATOM   405   C C   . LYS A 1 62  ? -2.758  28.866  -13.713  1.00 62.49  ? 55   LYS A C   1 
ATOM   406   O O   . LYS A 1 62  ? -3.470  29.481  -12.879  1.00 61.32  ? 55   LYS A O   1 
ATOM   407   C CB  . LYS A 1 62  ? -0.533  29.848  -14.334  1.00 67.53  ? 55   LYS A CB  1 
ATOM   408   C CG  . LYS A 1 62  ? 0.728   30.460  -13.732  1.00 70.39  ? 55   LYS A CG  1 
ATOM   409   C CD  . LYS A 1 62  ? 1.405   31.472  -14.642  1.00 70.03  ? 55   LYS A CD  1 
ATOM   410   C CE  . LYS A 1 62  ? 2.894   31.618  -14.393  1.00 69.87  ? 55   LYS A CE  1 
ATOM   411   N NZ  . LYS A 1 62  ? 3.686   30.911  -15.430  1.00 70.48  ? 55   LYS A NZ  1 
ATOM   412   N N   . SER A 1 63  ? -3.216  28.258  -14.823  1.00 58.06  ? 56   SER A N   1 
ATOM   413   C CA  . SER A 1 63  ? -4.638  28.164  -15.270  1.00 58.53  ? 56   SER A CA  1 
ATOM   414   C C   . SER A 1 63  ? -5.477  27.433  -14.208  1.00 55.63  ? 56   SER A C   1 
ATOM   415   O O   . SER A 1 63  ? -6.707  27.662  -14.132  1.00 51.65  ? 56   SER A O   1 
ATOM   416   C CB  . SER A 1 63  ? -4.762  27.522  -16.672  1.00 56.34  ? 56   SER A CB  1 
ATOM   417   O OG  . SER A 1 63  ? -4.709  26.092  -16.654  1.00 52.02  ? 56   SER A OG  1 
ATOM   418   N N   . VAL A 1 64  ? -4.830  26.582  -13.412  1.00 54.28  ? 57   VAL A N   1 
ATOM   419   C CA  . VAL A 1 64  ? -5.492  25.751  -12.367  1.00 60.08  ? 57   VAL A CA  1 
ATOM   420   C C   . VAL A 1 64  ? -5.039  26.217  -10.963  1.00 65.66  ? 57   VAL A C   1 
ATOM   421   O O   . VAL A 1 64  ? -5.026  25.369  -10.030  1.00 65.59  ? 57   VAL A O   1 
ATOM   422   C CB  . VAL A 1 64  ? -5.246  24.246  -12.622  1.00 56.41  ? 57   VAL A CB  1 
ATOM   423   C CG1 . VAL A 1 64  ? -6.053  23.726  -13.812  1.00 56.60  ? 57   VAL A CG1 1 
ATOM   424   C CG2 . VAL A 1 64  ? -3.765  23.904  -12.755  1.00 53.28  ? 57   VAL A CG2 1 
ATOM   425   N N   . THR A 1 65  ? -4.727  27.514  -10.785  1.00 69.22  ? 58   THR A N   1 
ATOM   426   C CA  . THR A 1 65  ? -4.337  28.119  -9.476   1.00 70.09  ? 58   THR A CA  1 
ATOM   427   C C   . THR A 1 65  ? -4.549  29.642  -9.467   1.00 76.24  ? 58   THR A C   1 
ATOM   428   O O   . THR A 1 65  ? -4.651  30.253  -10.570  1.00 75.92  ? 58   THR A O   1 
ATOM   429   C CB  . THR A 1 65  ? -2.866  27.846  -9.117   1.00 65.57  ? 58   THR A CB  1 
ATOM   430   O OG1 . THR A 1 65  ? -2.024  28.337  -10.162  1.00 63.58  ? 58   THR A OG1 1 
ATOM   431   C CG2 . THR A 1 65  ? -2.552  26.386  -8.870   1.00 62.82  ? 58   THR A CG2 1 
ATOM   432   N N   . ALA A 1 66  ? -4.598  30.212  -8.252   1.00 75.44  ? 59   ALA A N   1 
ATOM   433   C CA  . ALA A 1 66  ? -4.481  31.661  -7.975   1.00 74.17  ? 59   ALA A CA  1 
ATOM   434   C C   . ALA A 1 66  ? -2.991  31.983  -7.815   1.00 74.59  ? 59   ALA A C   1 
ATOM   435   O O   . ALA A 1 66  ? -2.426  31.585  -6.792   1.00 66.32  ? 59   ALA A O   1 
ATOM   436   C CB  . ALA A 1 66  ? -5.285  32.025  -6.747   1.00 71.82  ? 59   ALA A CB  1 
ATOM   437   N N   . GLY A 1 67  ? -2.393  32.629  -8.827   1.00 84.73  ? 60   GLY A N   1 
ATOM   438   C CA  . GLY A 1 67  ? -0.951  32.960  -8.946   1.00 89.27  ? 60   GLY A CA  1 
ATOM   439   C C   . GLY A 1 67  ? -0.201  32.915  -7.627   1.00 87.00  ? 60   GLY A C   1 
ATOM   440   O O   . GLY A 1 67  ? -0.792  33.309  -6.607   1.00 96.78  ? 60   GLY A O   1 
ATOM   441   N N   . GLY A 1 68  ? 1.067   32.484  -7.648   1.00 83.63  ? 61   GLY A N   1 
ATOM   442   C CA  . GLY A 1 68  ? 1.852   32.220  -6.424   1.00 75.08  ? 61   GLY A CA  1 
ATOM   443   C C   . GLY A 1 68  ? 1.655   30.791  -5.960   1.00 68.50  ? 61   GLY A C   1 
ATOM   444   O O   . GLY A 1 68  ? 2.645   30.195  -5.497   1.00 68.14  ? 61   GLY A O   1 
ATOM   445   N N   . ASP A 1 69  ? 0.432   30.262  -6.115   1.00 62.84  ? 62   ASP A N   1 
ATOM   446   C CA  . ASP A 1 69  ? 0.069   28.851  -5.816   1.00 66.41  ? 62   ASP A CA  1 
ATOM   447   C C   . ASP A 1 69  ? 0.591   27.900  -6.910   1.00 69.30  ? 62   ASP A C   1 
ATOM   448   O O   . ASP A 1 69  ? 0.867   26.732  -6.578   1.00 78.88  ? 62   ASP A O   1 
ATOM   449   C CB  . ASP A 1 69  ? -1.440  28.686  -5.605   1.00 67.88  ? 62   ASP A CB  1 
ATOM   450   C CG  . ASP A 1 69  ? -1.867  28.606  -4.140   1.00 69.65  ? 62   ASP A CG  1 
ATOM   451   O OD1 . ASP A 1 69  ? -1.070  28.092  -3.326   1.00 62.79  ? 62   ASP A OD1 1 
ATOM   452   O OD2 . ASP A 1 69  ? -3.027  28.978  -3.841   1.00 70.68  ? 62   ASP A OD2 1 
ATOM   453   N N   . TYR A 1 70  ? 0.713   28.347  -8.166   1.00 68.61  ? 63   TYR A N   1 
ATOM   454   C CA  . TYR A 1 70  ? 1.214   27.509  -9.292   1.00 67.66  ? 63   TYR A CA  1 
ATOM   455   C C   . TYR A 1 70  ? 2.634   27.028  -8.981   1.00 67.17  ? 63   TYR A C   1 
ATOM   456   O O   . TYR A 1 70  ? 2.980   25.897  -9.391   1.00 62.66  ? 63   TYR A O   1 
ATOM   457   C CB  . TYR A 1 70  ? 1.212   28.279  -10.611  1.00 68.22  ? 63   TYR A CB  1 
ATOM   458   C CG  . TYR A 1 70  ? 2.419   29.159  -10.807  1.00 71.26  ? 63   TYR A CG  1 
ATOM   459   C CD1 . TYR A 1 70  ? 2.459   30.435  -10.265  1.00 74.90  ? 63   TYR A CD1 1 
ATOM   460   C CD2 . TYR A 1 70  ? 3.526   28.722  -11.525  1.00 70.83  ? 63   TYR A CD2 1 
ATOM   461   C CE1 . TYR A 1 70  ? 3.563   31.260  -10.432  1.00 75.24  ? 63   TYR A CE1 1 
ATOM   462   C CE2 . TYR A 1 70  ? 4.642   29.532  -11.689  1.00 70.98  ? 63   TYR A CE2 1 
ATOM   463   C CZ  . TYR A 1 70  ? 4.659   30.810  -11.151  1.00 74.14  ? 63   TYR A CZ  1 
ATOM   464   O OH  . TYR A 1 70  ? 5.754   31.609  -11.324  1.00 76.76  ? 63   TYR A OH  1 
ATOM   465   N N   . GLY A 1 71  ? 3.402   27.874  -8.271   1.00 71.87  ? 64   GLY A N   1 
ATOM   466   C CA  . GLY A 1 71  ? 4.815   27.667  -7.876   1.00 69.32  ? 64   GLY A CA  1 
ATOM   467   C C   . GLY A 1 71  ? 4.961   26.922  -6.561   1.00 63.97  ? 64   GLY A C   1 
ATOM   468   O O   . GLY A 1 71  ? 5.898   27.264  -5.795   1.00 71.58  ? 64   GLY A O   1 
ATOM   469   N N   . ALA A 1 72  ? 4.070   25.950  -6.326   1.00 55.90  ? 65   ALA A N   1 
ATOM   470   C CA  . ALA A 1 72  ? 4.159   24.937  -5.254   1.00 46.49  ? 65   ALA A CA  1 
ATOM   471   C C   . ALA A 1 72  ? 5.059   23.794  -5.732   1.00 39.78  ? 65   ALA A C   1 
ATOM   472   O O   . ALA A 1 72  ? 4.844   23.290  -6.844   1.00 35.28  ? 65   ALA A O   1 
ATOM   473   C CB  . ALA A 1 72  ? 2.783   24.446  -4.880   1.00 46.04  ? 65   ALA A CB  1 
ATOM   474   N N   . VAL A 1 73  ? 6.038   23.435  -4.903   1.00 34.60  ? 66   VAL A N   1 
ATOM   475   C CA  . VAL A 1 73  ? 7.050   22.381  -5.171   1.00 33.30  ? 66   VAL A CA  1 
ATOM   476   C C   . VAL A 1 73  ? 6.839   21.244  -4.173   1.00 32.59  ? 66   VAL A C   1 
ATOM   477   O O   . VAL A 1 73  ? 6.928   21.508  -2.970   1.00 34.72  ? 66   VAL A O   1 
ATOM   478   C CB  . VAL A 1 73  ? 8.467   22.971  -5.071   1.00 34.07  ? 66   VAL A CB  1 
ATOM   479   C CG1 . VAL A 1 73  ? 9.525   21.969  -5.507   1.00 34.32  ? 66   VAL A CG1 1 
ATOM   480   C CG2 . VAL A 1 73  ? 8.579   24.260  -5.872   1.00 34.62  ? 66   VAL A CG2 1 
ATOM   481   N N   . GLU A 1 74  ? 6.566   20.037  -4.669   1.00 33.58  ? 67   GLU A N   1 
ATOM   482   C CA  . GLU A 1 74  ? 6.457   18.793  -3.858   1.00 36.56  ? 67   GLU A CA  1 
ATOM   483   C C   . GLU A 1 74  ? 7.720   18.622  -3.026   1.00 34.83  ? 67   GLU A C   1 
ATOM   484   O O   . GLU A 1 74  ? 8.782   18.924  -3.569   1.00 31.87  ? 67   GLU A O   1 
ATOM   485   C CB  . GLU A 1 74  ? 6.320   17.559  -4.750   1.00 41.49  ? 67   GLU A CB  1 
ATOM   486   C CG  . GLU A 1 74  ? 4.961   16.896  -4.607   1.00 47.16  ? 67   GLU A CG  1 
ATOM   487   C CD  . GLU A 1 74  ? 4.552   16.051  -5.793   1.00 50.00  ? 67   GLU A CD  1 
ATOM   488   O OE1 . GLU A 1 74  ? 4.964   16.399  -6.912   1.00 56.54  ? 67   GLU A OE1 1 
ATOM   489   O OE2 . GLU A 1 74  ? 3.828   15.051  -5.594   1.00 46.99  ? 67   GLU A OE2 1 
ATOM   490   N N   . TRP A 1 75  ? 7.601   18.121  -1.794   1.00 34.91  ? 68   TRP A N   1 
ATOM   491   C CA  . TRP A 1 75  ? 8.757   17.896  -0.887   1.00 36.38  ? 68   TRP A CA  1 
ATOM   492   C C   . TRP A 1 75  ? 8.720   16.486  -0.273   1.00 36.83  ? 68   TRP A C   1 
ATOM   493   O O   . TRP A 1 75  ? 9.714   15.731  -0.420   1.00 36.85  ? 68   TRP A O   1 
ATOM   494   C CB  . TRP A 1 75  ? 8.828   19.001  0.168    1.00 35.67  ? 68   TRP A CB  1 
ATOM   495   C CG  . TRP A 1 75  ? 10.070  18.923  1.007    1.00 37.30  ? 68   TRP A CG  1 
ATOM   496   C CD1 . TRP A 1 75  ? 10.119  18.791  2.364    1.00 38.59  ? 68   TRP A CD1 1 
ATOM   497   C CD2 . TRP A 1 75  ? 11.442  18.936  0.561    1.00 33.95  ? 68   TRP A CD2 1 
ATOM   498   N NE1 . TRP A 1 75  ? 11.417  18.724  2.791    1.00 39.70  ? 68   TRP A NE1 1 
ATOM   499   C CE2 . TRP A 1 75  ? 12.251  18.819  1.710    1.00 35.77  ? 68   TRP A CE2 1 
ATOM   500   C CE3 . TRP A 1 75  ? 12.067  19.033  -0.681   1.00 34.11  ? 68   TRP A CE3 1 
ATOM   501   C CZ2 . TRP A 1 75  ? 13.645  18.816  1.661    1.00 35.30  ? 68   TRP A CZ2 1 
ATOM   502   C CZ3 . TRP A 1 75  ? 13.444  19.039  -0.736   1.00 33.92  ? 68   TRP A CZ3 1 
ATOM   503   C CH2 . TRP A 1 75  ? 14.221  18.932  0.420    1.00 34.24  ? 68   TRP A CH2 1 
ATOM   504   N N   . GLN A 1 76  ? 7.631   16.107  0.396    1.00 37.68  ? 69   GLN A N   1 
ATOM   505   C CA  . GLN A 1 76  ? 7.545   14.767  1.035    1.00 36.26  ? 69   GLN A CA  1 
ATOM   506   C C   . GLN A 1 76  ? 6.080   14.390  1.263    1.00 33.88  ? 69   GLN A C   1 
ATOM   507   O O   . GLN A 1 76  ? 5.214   15.293  1.233    1.00 34.18  ? 69   GLN A O   1 
ATOM   508   C CB  . GLN A 1 76  ? 8.361   14.765  2.334    1.00 39.24  ? 69   GLN A CB  1 
ATOM   509   C CG  . GLN A 1 76  ? 7.766   15.674  3.407    1.00 41.18  ? 69   GLN A CG  1 
ATOM   510   C CD  . GLN A 1 76  ? 8.581   15.821  4.661    1.00 43.55  ? 69   GLN A CD  1 
ATOM   511   O OE1 . GLN A 1 76  ? 9.356   14.940  5.035    1.00 44.15  ? 69   GLN A OE1 1 
ATOM   512   N NE2 . GLN A 1 76  ? 8.396   16.963  5.304    1.00 43.36  ? 69   GLN A NE2 1 
ATOM   513   N N   . ALA A 1 77  ? 5.843   13.100  1.489    1.00 32.84  ? 70   ALA A N   1 
ATOM   514   C CA  . ALA A 1 77  ? 4.594   12.526  2.049    1.00 32.64  ? 70   ALA A CA  1 
ATOM   515   C C   . ALA A 1 77  ? 4.387   13.080  3.463    1.00 32.79  ? 70   ALA A C   1 
ATOM   516   O O   . ALA A 1 77  ? 5.382   13.112  4.218    1.00 30.80  ? 70   ALA A O   1 
ATOM   517   C CB  . ALA A 1 77  ? 4.706   11.013  2.073    1.00 32.32  ? 70   ALA A CB  1 
ATOM   518   N N   . GLY A 1 78  ? 3.160   13.480  3.809    1.00 31.76  ? 71   GLY A N   1 
ATOM   519   C CA  . GLY A 1 78  ? 2.772   13.885  5.175    1.00 30.93  ? 71   GLY A CA  1 
ATOM   520   C C   . GLY A 1 78  ? 2.367   12.679  6.003    1.00 31.84  ? 71   GLY A C   1 
ATOM   521   O O   . GLY A 1 78  ? 3.162   12.197  6.788    1.00 42.81  ? 71   GLY A O   1 
ATOM   522   N N   . SER A 1 79  ? 1.146   12.213  5.827    1.00 31.98  ? 72   SER A N   1 
ATOM   523   C CA  . SER A 1 79  ? 0.613   10.941  6.363    1.00 31.30  ? 72   SER A CA  1 
ATOM   524   C C   . SER A 1 79  ? 0.290   10.052  5.163    1.00 28.57  ? 72   SER A C   1 
ATOM   525   O O   . SER A 1 79  ? 0.663   10.446  4.057    1.00 29.39  ? 72   SER A O   1 
ATOM   526   C CB  . SER A 1 79  ? -0.605  11.230  7.208    1.00 35.06  ? 72   SER A CB  1 
ATOM   527   O OG  . SER A 1 79  ? -1.474  12.132  6.522    1.00 37.38  ? 72   SER A OG  1 
ATOM   528   N N   . LEU A 1 80  ? -0.407  8.933   5.356    1.00 27.23  ? 73   LEU A N   1 
ATOM   529   C CA  . LEU A 1 80  ? -0.833  8.039   4.248    1.00 27.95  ? 73   LEU A CA  1 
ATOM   530   C C   . LEU A 1 80  ? -1.502  8.843   3.133    1.00 26.05  ? 73   LEU A C   1 
ATOM   531   O O   . LEU A 1 80  ? -1.292  8.477   1.976    1.00 27.79  ? 73   LEU A O   1 
ATOM   532   C CB  . LEU A 1 80  ? -1.811  6.975   4.752    1.00 29.73  ? 73   LEU A CB  1 
ATOM   533   C CG  . LEU A 1 80  ? -1.175  5.653   5.181    1.00 31.44  ? 73   LEU A CG  1 
ATOM   534   C CD1 . LEU A 1 80  ? -2.217  4.743   5.807    1.00 33.28  ? 73   LEU A CD1 1 
ATOM   535   C CD2 . LEU A 1 80  ? -0.510  4.940   4.011    1.00 30.86  ? 73   LEU A CD2 1 
ATOM   536   N N   . ASN A 1 81  ? -2.285  9.870   3.456    1.00 23.23  ? 74   ASN A N   1 
ATOM   537   C CA  . ASN A 1 81  ? -3.241  10.473  2.490    1.00 22.73  ? 74   ASN A CA  1 
ATOM   538   C C   . ASN A 1 81  ? -2.920  11.948  2.256    1.00 22.85  ? 74   ASN A C   1 
ATOM   539   O O   . ASN A 1 81  ? -3.774  12.636  1.659    1.00 23.11  ? 74   ASN A O   1 
ATOM   540   C CB  . ASN A 1 81  ? -4.690  10.292  2.966    1.00 22.11  ? 74   ASN A CB  1 
ATOM   541   C CG  . ASN A 1 81  ? -4.981  8.857   3.348    1.00 20.85  ? 74   ASN A CG  1 
ATOM   542   O OD1 . ASN A 1 81  ? -4.647  7.940   2.608    1.00 20.09  ? 74   ASN A OD1 1 
ATOM   543   N ND2 . ASN A 1 81  ? -5.579  8.651   4.506    1.00 21.05  ? 74   ASN A ND2 1 
ATOM   544   N N   . THR A 1 82  ? -1.757  12.432  2.687    1.00 24.97  ? 75   THR A N   1 
ATOM   545   C CA  . THR A 1 82  ? -1.388  13.858  2.509    1.00 28.62  ? 75   THR A CA  1 
ATOM   546   C C   . THR A 1 82  ? -0.003  14.023  1.873    1.00 30.00  ? 75   THR A C   1 
ATOM   547   O O   . THR A 1 82  ? 0.852   13.124  1.995    1.00 29.75  ? 75   THR A O   1 
ATOM   548   C CB  . THR A 1 82  ? -1.497  14.630  3.824    1.00 30.36  ? 75   THR A CB  1 
ATOM   549   O OG1 . THR A 1 82  ? -0.568  14.074  4.751    1.00 37.70  ? 75   THR A OG1 1 
ATOM   550   C CG2 . THR A 1 82  ? -2.894  14.590  4.409    1.00 30.63  ? 75   THR A CG2 1 
ATOM   551   N N   . LEU A 1 83  ? 0.176   15.169  1.213    1.00 31.81  ? 76   LEU A N   1 
ATOM   552   C CA  . LEU A 1 83  ? 1.440   15.639  0.602    1.00 34.05  ? 76   LEU A CA  1 
ATOM   553   C C   . LEU A 1 83  ? 1.836   16.971  1.223    1.00 33.80  ? 76   LEU A C   1 
ATOM   554   O O   . LEU A 1 83  ? 0.938   17.787  1.494    1.00 31.96  ? 76   LEU A O   1 
ATOM   555   C CB  . LEU A 1 83  ? 1.244   15.814  -0.906   1.00 37.09  ? 76   LEU A CB  1 
ATOM   556   C CG  . LEU A 1 83  ? 1.137   14.508  -1.671   1.00 39.49  ? 76   LEU A CG  1 
ATOM   557   C CD1 . LEU A 1 83  ? 0.957   14.788  -3.147   1.00 42.17  ? 76   LEU A CD1 1 
ATOM   558   C CD2 . LEU A 1 83  ? 2.358   13.623  -1.403   1.00 39.54  ? 76   LEU A CD2 1 
ATOM   559   N N   . VAL A 1 84  ? 3.142   17.184  1.364    1.00 32.92  ? 77   VAL A N   1 
ATOM   560   C CA  . VAL A 1 84  ? 3.702   18.424  1.957    1.00 33.02  ? 77   VAL A CA  1 
ATOM   561   C C   . VAL A 1 84  ? 4.602   19.085  0.913    1.00 31.80  ? 77   VAL A C   1 
ATOM   562   O O   . VAL A 1 84  ? 5.471   18.391  0.379    1.00 31.69  ? 77   VAL A O   1 
ATOM   563   C CB  . VAL A 1 84  ? 4.438   18.107  3.268    1.00 32.70  ? 77   VAL A CB  1 
ATOM   564   C CG1 . VAL A 1 84  ? 4.917   19.377  3.935    1.00 32.85  ? 77   VAL A CG1 1 
ATOM   565   C CG2 . VAL A 1 84  ? 3.559   17.313  4.221    1.00 32.80  ? 77   VAL A CG2 1 
ATOM   566   N N   . ASP A 1 85  ? 4.374   20.372  0.635    1.00 32.46  ? 78   ASP A N   1 
ATOM   567   C CA  . ASP A 1 85  ? 5.230   21.198  -0.256   1.00 34.79  ? 78   ASP A CA  1 
ATOM   568   C C   . ASP A 1 85  ? 6.426   21.724  0.539    1.00 34.88  ? 78   ASP A C   1 
ATOM   569   O O   . ASP A 1 85  ? 6.509   21.457  1.766    1.00 36.21  ? 78   ASP A O   1 
ATOM   570   C CB  . ASP A 1 85  ? 4.454   22.316  -0.970   1.00 36.17  ? 78   ASP A CB  1 
ATOM   571   C CG  . ASP A 1 85  ? 4.051   23.519  -0.125   1.00 38.54  ? 78   ASP A CG  1 
ATOM   572   O OD1 . ASP A 1 85  ? 4.493   23.611  1.041    1.00 38.99  ? 78   ASP A OD1 1 
ATOM   573   O OD2 . ASP A 1 85  ? 3.280   24.361  -0.650   1.00 38.56  ? 78   ASP A OD2 1 
ATOM   574   N N   . THR A 1 86  ? 7.306   22.447  -0.155   1.00 35.22  ? 79   THR A N   1 
ATOM   575   C CA  . THR A 1 86  ? 8.578   23.008  0.374    1.00 36.95  ? 79   THR A CA  1 
ATOM   576   C C   . THR A 1 86  ? 8.305   24.072  1.453    1.00 38.27  ? 79   THR A C   1 
ATOM   577   O O   . THR A 1 86  ? 9.239   24.380  2.198    1.00 37.17  ? 79   THR A O   1 
ATOM   578   C CB  . THR A 1 86  ? 9.412   23.564  -0.786   1.00 33.46  ? 79   THR A CB  1 
ATOM   579   O OG1 . THR A 1 86  ? 8.586   24.457  -1.533   1.00 33.45  ? 79   THR A OG1 1 
ATOM   580   C CG2 . THR A 1 86  ? 9.953   22.470  -1.677   1.00 32.44  ? 79   THR A CG2 1 
ATOM   581   N N   . GLN A 1 87  ? 7.086   24.624  1.517    1.00 44.24  ? 80   GLN A N   1 
ATOM   582   C CA  . GLN A 1 87  ? 6.702   25.675  2.500    1.00 44.91  ? 80   GLN A CA  1 
ATOM   583   C C   . GLN A 1 87  ? 5.999   25.051  3.707    1.00 46.23  ? 80   GLN A C   1 
ATOM   584   O O   . GLN A 1 87  ? 5.545   25.827  4.592    1.00 46.79  ? 80   GLN A O   1 
ATOM   585   C CB  . GLN A 1 87  ? 5.789   26.701  1.839    1.00 46.47  ? 80   GLN A CB  1 
ATOM   586   C CG  . GLN A 1 87  ? 6.369   27.274  0.562    1.00 50.40  ? 80   GLN A CG  1 
ATOM   587   C CD  . GLN A 1 87  ? 5.303   28.050  -0.165   1.00 59.03  ? 80   GLN A CD  1 
ATOM   588   O OE1 . GLN A 1 87  ? 4.530   28.787  0.445    1.00 70.76  ? 80   GLN A OE1 1 
ATOM   589   N NE2 . GLN A 1 87  ? 5.221   27.844  -1.467   1.00 62.10  ? 80   GLN A NE2 1 
ATOM   590   N N   . GLY A 1 88  ? 5.896   23.717  3.740    1.00 47.32  ? 81   GLY A N   1 
ATOM   591   C CA  . GLY A 1 88  ? 5.301   22.959  4.862    1.00 45.21  ? 81   GLY A CA  1 
ATOM   592   C C   . GLY A 1 88  ? 3.787   22.860  4.777    1.00 43.59  ? 81   GLY A C   1 
ATOM   593   O O   . GLY A 1 88  ? 3.192   22.361  5.746    1.00 41.49  ? 81   GLY A O   1 
ATOM   594   N N   . GLN A 1 89  ? 3.179   23.298  3.671    1.00 44.24  ? 82   GLN A N   1 
ATOM   595   C CA  . GLN A 1 89  ? 1.708   23.232  3.499    1.00 46.41  ? 82   GLN A CA  1 
ATOM   596   C C   . GLN A 1 89  ? 1.337   21.781  3.164    1.00 42.02  ? 82   GLN A C   1 
ATOM   597   O O   . GLN A 1 89  ? 1.931   21.223  2.231    1.00 39.05  ? 82   GLN A O   1 
ATOM   598   C CB  . GLN A 1 89  ? 1.236   24.264  2.482    1.00 52.04  ? 82   GLN A CB  1 
ATOM   599   C CG  . GLN A 1 89  ? 1.298   25.685  3.003    1.00 59.27  ? 82   GLN A CG  1 
ATOM   600   C CD  . GLN A 1 89  ? 1.319   26.649  1.845    1.00 70.17  ? 82   GLN A CD  1 
ATOM   601   O OE1 . GLN A 1 89  ? 1.512   26.263  0.690    1.00 79.43  ? 82   GLN A OE1 1 
ATOM   602   N NE2 . GLN A 1 89  ? 1.133   27.922  2.143    1.00 74.50  ? 82   GLN A NE2 1 
ATOM   603   N N   . GLU A 1 90  ? 0.431   21.198  3.954    1.00 41.06  ? 83   GLU A N   1 
ATOM   604   C CA  . GLU A 1 90  ? -0.025  19.786  3.856    1.00 40.00  ? 83   GLU A CA  1 
ATOM   605   C C   . GLU A 1 90  ? -1.314  19.773  3.023    1.00 34.46  ? 83   GLU A C   1 
ATOM   606   O O   . GLU A 1 90  ? -2.191  20.610  3.263    1.00 38.44  ? 83   GLU A O   1 
ATOM   607   C CB  . GLU A 1 90  ? -0.223  19.182  5.255    1.00 41.32  ? 83   GLU A CB  1 
ATOM   608   C CG  . GLU A 1 90  ? -0.346  17.663  5.268    1.00 42.89  ? 83   GLU A CG  1 
ATOM   609   C CD  . GLU A 1 90  ? -0.523  17.003  6.631    1.00 43.65  ? 83   GLU A CD  1 
ATOM   610   O OE1 . GLU A 1 90  ? -1.366  17.493  7.394    1.00 48.10  ? 83   GLU A OE1 1 
ATOM   611   O OE2 . GLU A 1 90  ? 0.100   15.925  6.867    1.00 42.83  ? 83   GLU A OE2 1 
ATOM   612   N N   . PHE A 1 91  ? -1.394  18.892  2.037    1.00 29.50  ? 84   PHE A N   1 
ATOM   613   C CA  . PHE A 1 91  ? -2.540  18.758  1.110    1.00 29.03  ? 84   PHE A CA  1 
ATOM   614   C C   . PHE A 1 91  ? -3.183  17.411  1.374    1.00 27.37  ? 84   PHE A C   1 
ATOM   615   O O   . PHE A 1 91  ? -2.439  16.443  1.510    1.00 27.37  ? 84   PHE A O   1 
ATOM   616   C CB  . PHE A 1 91  ? -2.080  18.819  -0.349   1.00 29.06  ? 84   PHE A CB  1 
ATOM   617   C CG  . PHE A 1 91  ? -1.588  20.177  -0.766   1.00 29.55  ? 84   PHE A CG  1 
ATOM   618   C CD1 . PHE A 1 91  ? -0.327  20.622  -0.397   1.00 30.93  ? 84   PHE A CD1 1 
ATOM   619   C CD2 . PHE A 1 91  ? -2.404  21.022  -1.498   1.00 29.82  ? 84   PHE A CD2 1 
ATOM   620   C CE1 . PHE A 1 91  ? 0.108   21.891  -0.745   1.00 31.61  ? 84   PHE A CE1 1 
ATOM   621   C CE2 . PHE A 1 91  ? -1.965  22.289  -1.857   1.00 30.95  ? 84   PHE A CE2 1 
ATOM   622   C CZ  . PHE A 1 91  ? -0.711  22.724  -1.471   1.00 32.21  ? 84   PHE A CZ  1 
ATOM   623   N N   . ILE A 1 92  ? -4.504  17.361  1.433    1.00 27.03  ? 85   ILE A N   1 
ATOM   624   C CA  . ILE A 1 92  ? -5.242  16.076  1.317    1.00 29.02  ? 85   ILE A CA  1 
ATOM   625   C C   . ILE A 1 92  ? -5.182  15.697  -0.160   1.00 28.70  ? 85   ILE A C   1 
ATOM   626   O O   . ILE A 1 92  ? -5.418  16.584  -1.000   1.00 28.37  ? 85   ILE A O   1 
ATOM   627   C CB  . ILE A 1 92  ? -6.689  16.192  1.839    1.00 31.13  ? 85   ILE A CB  1 
ATOM   628   C CG1 . ILE A 1 92  ? -6.714  16.422  3.355    1.00 30.29  ? 85   ILE A CG1 1 
ATOM   629   C CG2 . ILE A 1 92  ? -7.510  14.967  1.444    1.00 30.55  ? 85   ILE A CG2 1 
ATOM   630   C CD1 . ILE A 1 92  ? -7.992  17.027  3.856    1.00 30.01  ? 85   ILE A CD1 1 
ATOM   631   N N   . ASP A 1 93  ? -4.839  14.443  -0.453   1.00 29.39  ? 86   ASP A N   1 
ATOM   632   C CA  . ASP A 1 93  ? -4.584  13.973  -1.833   1.00 30.97  ? 86   ASP A CA  1 
ATOM   633   C C   . ASP A 1 93  ? -5.831  13.289  -2.392   1.00 29.51  ? 86   ASP A C   1 
ATOM   634   O O   . ASP A 1 93  ? -6.035  12.115  -2.094   1.00 28.46  ? 86   ASP A O   1 
ATOM   635   C CB  . ASP A 1 93  ? -3.358  13.060  -1.893   1.00 32.01  ? 86   ASP A CB  1 
ATOM   636   C CG  . ASP A 1 93  ? -2.963  12.749  -3.331   1.00 32.03  ? 86   ASP A CG  1 
ATOM   637   O OD1 . ASP A 1 93  ? -3.669  13.230  -4.269   1.00 31.98  ? 86   ASP A OD1 1 
ATOM   638   O OD2 . ASP A 1 93  ? -1.970  12.029  -3.510   1.00 32.42  ? 86   ASP A OD2 1 
ATOM   639   N N   . CYS A 1 94  ? -6.592  14.004  -3.219   1.00 32.53  ? 87   CYS A N   1 
ATOM   640   C CA  . CYS A 1 94  ? -7.734  13.480  -4.009   1.00 34.10  ? 87   CYS A CA  1 
ATOM   641   C C   . CYS A 1 94  ? -7.380  13.318  -5.494   1.00 33.84  ? 87   CYS A C   1 
ATOM   642   O O   . CYS A 1 94  ? -8.290  12.993  -6.293   1.00 33.73  ? 87   CYS A O   1 
ATOM   643   C CB  . CYS A 1 94  ? -8.915  14.419  -3.882   1.00 36.79  ? 87   CYS A CB  1 
ATOM   644   S SG  . CYS A 1 94  ? -9.654  14.315  -2.244   1.00 41.24  ? 87   CYS A SG  1 
ATOM   645   N N   . LEU A 1 95  ? -6.123  13.555  -5.849   1.00 30.92  ? 88   LEU A N   1 
ATOM   646   C CA  . LEU A 1 95  ? -5.576  13.260  -7.187   1.00 32.18  ? 88   LEU A CA  1 
ATOM   647   C C   . LEU A 1 95  ? -5.082  11.809  -7.208   1.00 32.05  ? 88   LEU A C   1 
ATOM   648   O O   . LEU A 1 95  ? -5.301  11.121  -8.231   1.00 29.96  ? 88   LEU A O   1 
ATOM   649   C CB  . LEU A 1 95  ? -4.451  14.259  -7.460   1.00 33.67  ? 88   LEU A CB  1 
ATOM   650   C CG  . LEU A 1 95  ? -3.813  14.167  -8.839   1.00 36.78  ? 88   LEU A CG  1 
ATOM   651   C CD1 . LEU A 1 95  ? -4.881  14.093  -9.930   1.00 38.05  ? 88   LEU A CD1 1 
ATOM   652   C CD2 . LEU A 1 95  ? -2.877  15.341  -9.067   1.00 37.52  ? 88   LEU A CD2 1 
ATOM   653   N N   . GLY A 1 96  ? -4.461  11.359  -6.111   1.00 32.52  ? 89   GLY A N   1 
ATOM   654   C CA  . GLY A 1 96  ? -3.868  10.012  -5.971   1.00 34.03  ? 89   GLY A CA  1 
ATOM   655   C C   . GLY A 1 96  ? -2.820  9.712   -7.042   1.00 33.22  ? 89   GLY A C   1 
ATOM   656   O O   . GLY A 1 96  ? -2.678  8.531   -7.429   1.00 32.44  ? 89   GLY A O   1 
ATOM   657   N N   . GLY A 1 97  ? -2.094  10.726  -7.503   1.00 32.44  ? 90   GLY A N   1 
ATOM   658   C CA  . GLY A 1 97  ? -1.171  10.585  -8.646   1.00 34.33  ? 90   GLY A CA  1 
ATOM   659   C C   . GLY A 1 97  ? -1.867  9.912   -9.821   1.00 37.03  ? 90   GLY A C   1 
ATOM   660   O O   . GLY A 1 97  ? -1.243  9.087   -10.481  1.00 40.14  ? 90   GLY A O   1 
ATOM   661   N N   . PHE A 1 98  ? -3.138  10.228  -10.062  1.00 35.36  ? 91   PHE A N   1 
ATOM   662   C CA  . PHE A 1 98  ? -3.913  9.707   -11.212  1.00 36.54  ? 91   PHE A CA  1 
ATOM   663   C C   . PHE A 1 98  ? -4.120  8.194   -11.054  1.00 35.14  ? 91   PHE A C   1 
ATOM   664   O O   . PHE A 1 98  ? -4.221  7.493   -12.087  1.00 38.44  ? 91   PHE A O   1 
ATOM   665   C CB  . PHE A 1 98  ? -3.211  10.112  -12.517  1.00 38.48  ? 91   PHE A CB  1 
ATOM   666   C CG  . PHE A 1 98  ? -3.118  11.606  -12.733  1.00 40.44  ? 91   PHE A CG  1 
ATOM   667   C CD1 . PHE A 1 98  ? -4.158  12.305  -13.333  1.00 39.73  ? 91   PHE A CD1 1 
ATOM   668   C CD2 . PHE A 1 98  ? -2.016  12.330  -12.297  1.00 43.15  ? 91   PHE A CD2 1 
ATOM   669   C CE1 . PHE A 1 98  ? -4.096  13.680  -13.507  1.00 39.37  ? 91   PHE A CE1 1 
ATOM   670   C CE2 . PHE A 1 98  ? -1.953  13.707  -12.478  1.00 42.77  ? 91   PHE A CE2 1 
ATOM   671   C CZ  . PHE A 1 98  ? -2.990  14.379  -13.090  1.00 39.98  ? 91   PHE A CZ  1 
ATOM   672   N N   . GLY A 1 99  ? -4.225  7.710   -9.813   1.00 31.59  ? 92   GLY A N   1 
ATOM   673   C CA  . GLY A 1 99  ? -4.608  6.320   -9.486   1.00 29.80  ? 92   GLY A CA  1 
ATOM   674   C C   . GLY A 1 99  ? -3.416  5.449   -9.123   1.00 28.36  ? 92   GLY A C   1 
ATOM   675   O O   . GLY A 1 99  ? -3.521  4.221   -9.232   1.00 27.77  ? 92   GLY A O   1 
ATOM   676   N N   . ILE A 1 100 ? -2.332  6.055   -8.664   1.00 27.29  ? 93   ILE A N   1 
ATOM   677   C CA  . ILE A 1 100 ? -1.103  5.335   -8.235   1.00 30.98  ? 93   ILE A CA  1 
ATOM   678   C C   . ILE A 1 100 ? -1.190  4.973   -6.750   1.00 29.51  ? 93   ILE A C   1 
ATOM   679   O O   . ILE A 1 100 ? -0.816  3.839   -6.395   1.00 28.23  ? 93   ILE A O   1 
ATOM   680   C CB  . ILE A 1 100 ? 0.114   6.227   -8.492   1.00 33.21  ? 93   ILE A CB  1 
ATOM   681   C CG1 . ILE A 1 100 ? 0.262   6.547   -9.977   1.00 38.21  ? 93   ILE A CG1 1 
ATOM   682   C CG2 . ILE A 1 100 ? 1.368   5.600   -7.945   1.00 32.98  ? 93   ILE A CG2 1 
ATOM   683   C CD1 . ILE A 1 100 ? 1.254   7.663   -10.227  1.00 41.45  ? 93   ILE A CD1 1 
ATOM   684   N N   . PHE A 1 101 ? -1.621  5.929   -5.923   1.00 27.09  ? 94   PHE A N   1 
ATOM   685   C CA  . PHE A 1 101 ? -1.447  5.917   -4.450   1.00 25.94  ? 94   PHE A CA  1 
ATOM   686   C C   . PHE A 1 101 ? -2.649  5.232   -3.786   1.00 25.46  ? 94   PHE A C   1 
ATOM   687   O O   . PHE A 1 101 ? -3.218  5.831   -2.857   1.00 25.63  ? 94   PHE A O   1 
ATOM   688   C CB  . PHE A 1 101 ? -1.215  7.345   -3.955   1.00 25.87  ? 94   PHE A CB  1 
ATOM   689   C CG  . PHE A 1 101 ? 0.037   7.996   -4.490   1.00 27.06  ? 94   PHE A CG  1 
ATOM   690   C CD1 . PHE A 1 101 ? 1.297   7.488   -4.194   1.00 28.16  ? 94   PHE A CD1 1 
ATOM   691   C CD2 . PHE A 1 101 ? -0.041  9.124   -5.290   1.00 27.76  ? 94   PHE A CD2 1 
ATOM   692   C CE1 . PHE A 1 101 ? 2.448   8.107   -4.664   1.00 27.09  ? 94   PHE A CE1 1 
ATOM   693   C CE2 . PHE A 1 101 ? 1.106   9.731   -5.785   1.00 28.17  ? 94   PHE A CE2 1 
ATOM   694   C CZ  . PHE A 1 101 ? 2.351   9.227   -5.460   1.00 28.30  ? 94   PHE A CZ  1 
ATOM   695   N N   . ASN A 1 102 ? -2.992  4.016   -4.237   1.00 25.36  ? 95   ASN A N   1 
ATOM   696   C CA  . ASN A 1 102 ? -4.175  3.235   -3.777   1.00 23.43  ? 95   ASN A CA  1 
ATOM   697   C C   . ASN A 1 102 ? -3.998  2.885   -2.303   1.00 21.80  ? 95   ASN A C   1 
ATOM   698   O O   . ASN A 1 102 ? -5.003  2.945   -1.553   1.00 19.51  ? 95   ASN A O   1 
ATOM   699   C CB  . ASN A 1 102 ? -4.391  1.962   -4.595   1.00 24.21  ? 95   ASN A CB  1 
ATOM   700   C CG  . ASN A 1 102 ? -5.052  2.247   -5.925   1.00 24.08  ? 95   ASN A CG  1 
ATOM   701   O OD1 . ASN A 1 102 ? -4.999  3.371   -6.414   1.00 24.21  ? 95   ASN A OD1 1 
ATOM   702   N ND2 . ASN A 1 102 ? -5.687  1.247   -6.508   1.00 23.88  ? 95   ASN A ND2 1 
ATOM   703   N N   . VAL A 1 103 ? -2.769  2.568   -1.901   1.00 19.37  ? 96   VAL A N   1 
ATOM   704   C CA  . VAL A 1 103 ? -2.462  2.160   -0.499   1.00 18.49  ? 96   VAL A CA  1 
ATOM   705   C C   . VAL A 1 103 ? -1.752  3.314   0.222    1.00 17.91  ? 96   VAL A C   1 
ATOM   706   O O   . VAL A 1 103 ? -1.105  3.065   1.236    1.00 16.29  ? 96   VAL A O   1 
ATOM   707   C CB  . VAL A 1 103 ? -1.652  0.853   -0.477   1.00 18.82  ? 96   VAL A CB  1 
ATOM   708   C CG1 . VAL A 1 103 ? -2.464  -0.290  -1.064   1.00 18.60  ? 96   VAL A CG1 1 
ATOM   709   C CG2 . VAL A 1 103 ? -0.296  0.987   -1.175   1.00 18.83  ? 96   VAL A CG2 1 
ATOM   710   N N   . GLY A 1 104 ? -1.917  4.537   -0.273   1.00 18.89  ? 97   GLY A N   1 
ATOM   711   C CA  . GLY A 1 104 ? -1.428  5.759   0.382    1.00 19.71  ? 97   GLY A CA  1 
ATOM   712   C C   . GLY A 1 104 ? 0.010   6.067   0.021    1.00 20.98  ? 97   GLY A C   1 
ATOM   713   O O   . GLY A 1 104 ? 0.595   5.340   -0.791   1.00 18.49  ? 97   GLY A O   1 
ATOM   714   N N   . HIS A 1 105 ? 0.522   7.148   0.612    1.00 22.94  ? 98   HIS A N   1 
ATOM   715   C CA  . HIS A 1 105 ? 1.890   7.691   0.450    1.00 24.59  ? 98   HIS A CA  1 
ATOM   716   C C   . HIS A 1 105 ? 2.812   7.002   1.456    1.00 25.74  ? 98   HIS A C   1 
ATOM   717   O O   . HIS A 1 105 ? 2.488   7.023   2.678    1.00 25.04  ? 98   HIS A O   1 
ATOM   718   C CB  . HIS A 1 105 ? 1.886   9.220   0.605    1.00 25.91  ? 98   HIS A CB  1 
ATOM   719   C CG  . HIS A 1 105 ? 1.223   9.914   -0.533   1.00 28.21  ? 98   HIS A CG  1 
ATOM   720   N ND1 . HIS A 1 105 ? 1.886   10.178  -1.712   1.00 31.54  ? 98   HIS A ND1 1 
ATOM   721   C CD2 . HIS A 1 105 ? -0.038  10.368  -0.692   1.00 31.78  ? 98   HIS A CD2 1 
ATOM   722   C CE1 . HIS A 1 105 ? 1.060   10.770  -2.553   1.00 33.47  ? 98   HIS A CE1 1 
ATOM   723   N NE2 . HIS A 1 105 ? -0.121  10.911  -1.947   1.00 33.58  ? 98   HIS A NE2 1 
ATOM   724   N N   . ARG A 1 106 ? 3.908   6.415   0.962    1.00 25.78  ? 99   ARG A N   1 
ATOM   725   C CA  . ARG A 1 106 ? 4.913   5.707   1.799    1.00 27.06  ? 99   ARG A CA  1 
ATOM   726   C C   . ARG A 1 106 ? 4.157   4.726   2.704    1.00 24.39  ? 99   ARG A C   1 
ATOM   727   O O   . ARG A 1 106 ? 4.262   4.824   3.940    1.00 23.64  ? 99   ARG A O   1 
ATOM   728   C CB  . ARG A 1 106 ? 5.752   6.705   2.606    1.00 27.71  ? 99   ARG A CB  1 
ATOM   729   C CG  . ARG A 1 106 ? 6.514   7.688   1.733    1.00 28.33  ? 99   ARG A CG  1 
ATOM   730   C CD  . ARG A 1 106 ? 7.654   8.427   2.412    1.00 30.71  ? 99   ARG A CD  1 
ATOM   731   N NE  . ARG A 1 106 ? 8.610   7.542   3.087    1.00 33.91  ? 99   ARG A NE  1 
ATOM   732   C CZ  . ARG A 1 106 ? 8.640   7.288   4.404    1.00 35.68  ? 99   ARG A CZ  1 
ATOM   733   N NH1 . ARG A 1 106 ? 7.762   7.855   5.215    1.00 36.57  ? 99   ARG A NH1 1 
ATOM   734   N NH2 . ARG A 1 106 ? 9.531   6.452   4.911    1.00 36.76  ? 99   ARG A NH2 1 
ATOM   735   N N   . ASN A 1 107 ? 3.381   3.839   2.095    1.00 21.43  ? 100  ASN A N   1 
ATOM   736   C CA  . ASN A 1 107 ? 2.740   2.755   2.862    1.00 20.01  ? 100  ASN A CA  1 
ATOM   737   C C   . ASN A 1 107 ? 3.861   1.975   3.522    1.00 18.93  ? 100  ASN A C   1 
ATOM   738   O O   . ASN A 1 107 ? 4.756   1.478   2.854    1.00 17.69  ? 100  ASN A O   1 
ATOM   739   C CB  . ASN A 1 107 ? 1.818   1.893   2.021    1.00 19.19  ? 100  ASN A CB  1 
ATOM   740   C CG  . ASN A 1 107 ? 1.139   0.849   2.876    1.00 18.89  ? 100  ASN A CG  1 
ATOM   741   O OD1 . ASN A 1 107 ? 1.813   -0.023  3.416    1.00 18.61  ? 100  ASN A OD1 1 
ATOM   742   N ND2 . ASN A 1 107 ? -0.175  0.947   3.013    1.00 18.85  ? 100  ASN A ND2 1 
ATOM   743   N N   . PRO A 1 108 ? 3.880   1.893   4.869    1.00 20.28  ? 101  PRO A N   1 
ATOM   744   C CA  . PRO A 1 108 ? 5.048   1.368   5.570    1.00 21.39  ? 101  PRO A CA  1 
ATOM   745   C C   . PRO A 1 108 ? 5.376   -0.065  5.127    1.00 21.52  ? 101  PRO A C   1 
ATOM   746   O O   . PRO A 1 108 ? 6.542   -0.423  5.146    1.00 22.85  ? 101  PRO A O   1 
ATOM   747   C CB  . PRO A 1 108 ? 4.668   1.425   7.052    1.00 20.58  ? 101  PRO A CB  1 
ATOM   748   C CG  . PRO A 1 108 ? 3.536   2.431   7.110    1.00 21.26  ? 101  PRO A CG  1 
ATOM   749   C CD  . PRO A 1 108 ? 2.811   2.307   5.788    1.00 20.61  ? 101  PRO A CD  1 
ATOM   750   N N   . VAL A 1 109 ? 4.358   -0.854  4.771    1.00 19.96  ? 102  VAL A N   1 
ATOM   751   C CA  . VAL A 1 109 ? 4.549   -2.269  4.343    1.00 19.33  ? 102  VAL A CA  1 
ATOM   752   C C   . VAL A 1 109 ? 5.277   -2.271  2.996    1.00 19.66  ? 102  VAL A C   1 
ATOM   753   O O   . VAL A 1 109 ? 6.159   -3.126  2.794    1.00 19.50  ? 102  VAL A O   1 
ATOM   754   C CB  . VAL A 1 109 ? 3.201   -3.009  4.268    1.00 19.64  ? 102  VAL A CB  1 
ATOM   755   C CG1 . VAL A 1 109 ? 3.308   -4.342  3.530    1.00 18.61  ? 102  VAL A CG1 1 
ATOM   756   C CG2 . VAL A 1 109 ? 2.595   -3.181  5.663    1.00 19.86  ? 102  VAL A CG2 1 
ATOM   757   N N   . VAL A 1 110 ? 4.910   -1.357  2.101    1.00 18.99  ? 103  VAL A N   1 
ATOM   758   C CA  . VAL A 1 110 ? 5.529   -1.273  0.749    1.00 19.29  ? 103  VAL A CA  1 
ATOM   759   C C   . VAL A 1 110 ? 6.943   -0.706  0.934    1.00 18.72  ? 103  VAL A C   1 
ATOM   760   O O   . VAL A 1 110 ? 7.900   -1.302  0.421    1.00 18.50  ? 103  VAL A O   1 
ATOM   761   C CB  . VAL A 1 110 ? 4.683   -0.440  -0.234   1.00 18.69  ? 103  VAL A CB  1 
ATOM   762   C CG1 . VAL A 1 110 ? 5.320   -0.413  -1.606   1.00 19.30  ? 103  VAL A CG1 1 
ATOM   763   C CG2 . VAL A 1 110 ? 3.252   -0.935  -0.332   1.00 19.38  ? 103  VAL A CG2 1 
ATOM   764   N N   . VAL A 1 111 ? 7.067   0.400   1.661    1.00 18.25  ? 104  VAL A N   1 
ATOM   765   C CA  . VAL A 1 111 ? 8.384   1.051   1.875    1.00 17.85  ? 104  VAL A CA  1 
ATOM   766   C C   . VAL A 1 111 ? 9.323   -0.020  2.429    1.00 17.11  ? 104  VAL A C   1 
ATOM   767   O O   . VAL A 1 111 ? 10.445  -0.151  1.920    1.00 15.94  ? 104  VAL A O   1 
ATOM   768   C CB  . VAL A 1 111 ? 8.246   2.274   2.794    1.00 19.02  ? 104  VAL A CB  1 
ATOM   769   C CG1 . VAL A 1 111 ? 9.586   2.747   3.359    1.00 19.40  ? 104  VAL A CG1 1 
ATOM   770   C CG2 . VAL A 1 111 ? 7.506   3.389   2.072    1.00 19.16  ? 104  VAL A CG2 1 
ATOM   771   N N   . SER A 1 112 ? 8.832   -0.813  3.382    1.00 16.90  ? 105  SER A N   1 
ATOM   772   C CA  . SER A 1 112 ? 9.618   -1.869  4.062    1.00 17.95  ? 105  SER A CA  1 
ATOM   773   C C   . SER A 1 112 ? 10.129  -2.892  3.050    1.00 17.28  ? 105  SER A C   1 
ATOM   774   O O   . SER A 1 112 ? 11.281  -3.262  3.112    1.00 15.70  ? 105  SER A O   1 
ATOM   775   C CB  . SER A 1 112 ? 8.815   -2.547  5.123    1.00 19.02  ? 105  SER A CB  1 
ATOM   776   O OG  . SER A 1 112 ? 9.540   -3.649  5.655    1.00 20.48  ? 105  SER A OG  1 
ATOM   777   N N   . ALA A 1 113 ? 9.257   -3.382  2.183    1.00 18.38  ? 106  ALA A N   1 
ATOM   778   C CA  . ALA A 1 113 ? 9.594   -4.448  1.216    1.00 18.69  ? 106  ALA A CA  1 
ATOM   779   C C   . ALA A 1 113 ? 10.680  -3.930  0.272    1.00 19.31  ? 106  ALA A C   1 
ATOM   780   O O   . ALA A 1 113 ? 11.673  -4.667  0.010    1.00 18.55  ? 106  ALA A O   1 
ATOM   781   C CB  . ALA A 1 113 ? 8.366   -4.871  0.478    1.00 18.70  ? 106  ALA A CB  1 
ATOM   782   N N   . VAL A 1 114 ? 10.529  -2.681  -0.169   1.00 19.22  ? 107  VAL A N   1 
ATOM   783   C CA  . VAL A 1 114 ? 11.486  -2.033  -1.107   1.00 19.49  ? 107  VAL A CA  1 
ATOM   784   C C   . VAL A 1 114 ? 12.849  -1.887  -0.404   1.00 19.56  ? 107  VAL A C   1 
ATOM   785   O O   . VAL A 1 114 ? 13.880  -2.371  -0.953   1.00 19.22  ? 107  VAL A O   1 
ATOM   786   C CB  . VAL A 1 114 ? 10.890  -0.718  -1.642   1.00 19.70  ? 107  VAL A CB  1 
ATOM   787   C CG1 . VAL A 1 114 ? 11.922  0.150   -2.359   1.00 19.31  ? 107  VAL A CG1 1 
ATOM   788   C CG2 . VAL A 1 114 ? 9.696   -1.020  -2.560   1.00 19.57  ? 107  VAL A CG2 1 
ATOM   789   N N   A GLN A 1 115 ? 12.857  -1.260  0.775    0.57 19.98  ? 108  GLN A N   1 
ATOM   790   N N   B GLN A 1 115 ? 12.857  -1.261  0.776    0.43 19.83  ? 108  GLN A N   1 
ATOM   791   C CA  A GLN A 1 115 ? 14.062  -1.101  1.634    0.57 19.67  ? 108  GLN A CA  1 
ATOM   792   C CA  B GLN A 1 115 ? 14.059  -1.102  1.639    0.43 19.57  ? 108  GLN A CA  1 
ATOM   793   C C   A GLN A 1 115 ? 14.779  -2.446  1.778    0.57 18.80  ? 108  GLN A C   1 
ATOM   794   C C   B GLN A 1 115 ? 14.779  -2.447  1.779    0.43 18.85  ? 108  GLN A C   1 
ATOM   795   O O   A GLN A 1 115 ? 16.012  -2.466  1.625    0.57 18.47  ? 108  GLN A O   1 
ATOM   796   O O   B GLN A 1 115 ? 16.012  -2.466  1.626    0.43 18.58  ? 108  GLN A O   1 
ATOM   797   C CB  A GLN A 1 115 ? 13.669  -0.613  3.026    0.57 20.65  ? 108  GLN A CB  1 
ATOM   798   C CB  B GLN A 1 115 ? 13.652  -0.597  3.022    0.43 20.34  ? 108  GLN A CB  1 
ATOM   799   C CG  A GLN A 1 115 ? 13.464  0.890   3.140    0.57 21.17  ? 108  GLN A CG  1 
ATOM   800   C CG  B GLN A 1 115 ? 14.798  0.024   3.798    0.43 20.84  ? 108  GLN A CG  1 
ATOM   801   C CD  A GLN A 1 115 ? 13.142  1.268   4.566    0.57 21.66  ? 108  GLN A CD  1 
ATOM   802   C CD  B GLN A 1 115 ? 15.512  1.049   2.959    0.43 21.03  ? 108  GLN A CD  1 
ATOM   803   O OE1 A GLN A 1 115 ? 12.521  0.504   5.303    0.57 20.23  ? 108  GLN A OE1 1 
ATOM   804   O OE1 B GLN A 1 115 ? 16.669  0.871   2.589    0.43 22.31  ? 108  GLN A OE1 1 
ATOM   805   N NE2 A GLN A 1 115 ? 13.634  2.425   4.990    0.57 22.12  ? 108  GLN A NE2 1 
ATOM   806   N NE2 B GLN A 1 115 ? 14.811  2.125   2.641    0.43 20.82  ? 108  GLN A NE2 1 
ATOM   807   N N   . ASN A 1 116 ? 14.029  -3.515  2.068    1.00 18.50  ? 109  ASN A N   1 
ATOM   808   C CA  . ASN A 1 116 ? 14.573  -4.875  2.327    1.00 19.03  ? 109  ASN A CA  1 
ATOM   809   C C   . ASN A 1 116 ? 15.246  -5.419  1.063    1.00 19.59  ? 109  ASN A C   1 
ATOM   810   O O   . ASN A 1 116 ? 16.377  -5.950  1.160    1.00 18.94  ? 109  ASN A O   1 
ATOM   811   C CB  . ASN A 1 116 ? 13.502  -5.858  2.807    1.00 20.15  ? 109  ASN A CB  1 
ATOM   812   C CG  . ASN A 1 116 ? 13.231  -5.811  4.298    1.00 20.17  ? 109  ASN A CG  1 
ATOM   813   O OD1 . ASN A 1 116 ? 14.149  -5.684  5.089    1.00 22.15  ? 109  ASN A OD1 1 
ATOM   814   N ND2 . ASN A 1 116 ? 11.983  -5.948  4.702    1.00 20.10  ? 109  ASN A ND2 1 
ATOM   815   N N   . GLN A 1 117 ? 14.597  -5.274  -0.094   1.00 20.76  ? 110  GLN A N   1 
ATOM   816   C CA  . GLN A 1 117 ? 15.142  -5.799  -1.378   1.00 18.72  ? 110  GLN A CA  1 
ATOM   817   C C   . GLN A 1 117 ? 16.324  -4.934  -1.816   1.00 19.09  ? 110  GLN A C   1 
ATOM   818   O O   . GLN A 1 117 ? 17.313  -5.493  -2.325   1.00 19.91  ? 110  GLN A O   1 
ATOM   819   C CB  . GLN A 1 117 ? 14.053  -5.869  -2.444   1.00 18.36  ? 110  GLN A CB  1 
ATOM   820   C CG  . GLN A 1 117 ? 14.433  -6.729  -3.634   1.00 17.60  ? 110  GLN A CG  1 
ATOM   821   C CD  . GLN A 1 117 ? 14.937  -8.098  -3.242   1.00 18.24  ? 110  GLN A CD  1 
ATOM   822   O OE1 . GLN A 1 117 ? 14.423  -8.755  -2.352   1.00 19.18  ? 110  GLN A OE1 1 
ATOM   823   N NE2 . GLN A 1 117 ? 15.979  -8.553  -3.909   1.00 19.39  ? 110  GLN A NE2 1 
ATOM   824   N N   . LEU A 1 118 ? 16.242  -3.618  -1.618   1.00 18.44  ? 111  LEU A N   1 
ATOM   825   C CA  . LEU A 1 118 ? 17.359  -2.686  -1.923   1.00 18.06  ? 111  LEU A CA  1 
ATOM   826   C C   . LEU A 1 118 ? 18.631  -3.145  -1.200   1.00 19.05  ? 111  LEU A C   1 
ATOM   827   O O   . LEU A 1 118 ? 19.715  -2.999  -1.761   1.00 18.53  ? 111  LEU A O   1 
ATOM   828   C CB  . LEU A 1 118 ? 16.933  -1.278  -1.500   1.00 17.60  ? 111  LEU A CB  1 
ATOM   829   C CG  . LEU A 1 118 ? 17.919  -0.152  -1.759   1.00 17.53  ? 111  LEU A CG  1 
ATOM   830   C CD1 . LEU A 1 118 ? 18.356  -0.142  -3.218   1.00 17.29  ? 111  LEU A CD1 1 
ATOM   831   C CD2 . LEU A 1 118 ? 17.292  1.186   -1.374   1.00 17.56  ? 111  LEU A CD2 1 
ATOM   832   N N   . ALA A 1 119 ? 18.508  -3.716  -0.003   1.00 20.34  ? 112  ALA A N   1 
ATOM   833   C CA  . ALA A 1 119 ? 19.654  -4.206  0.799    1.00 20.59  ? 112  ALA A CA  1 
ATOM   834   C C   . ALA A 1 119 ? 20.280  -5.457  0.167    1.00 22.08  ? 112  ALA A C   1 
ATOM   835   O O   . ALA A 1 119 ? 21.456  -5.727  0.490    1.00 25.97  ? 112  ALA A O   1 
ATOM   836   C CB  . ALA A 1 119 ? 19.231  -4.467  2.214    1.00 19.59  ? 112  ALA A CB  1 
ATOM   837   N N   . LYS A 1 120 ? 19.561  -6.197  -0.687   1.00 22.11  ? 113  LYS A N   1 
ATOM   838   C CA  . LYS A 1 120 ? 20.064  -7.452  -1.319   1.00 22.46  ? 113  LYS A CA  1 
ATOM   839   C C   . LYS A 1 120 ? 20.426  -7.249  -2.797   1.00 23.23  ? 113  LYS A C   1 
ATOM   840   O O   . LYS A 1 120 ? 21.590  -7.500  -3.166   1.00 24.67  ? 113  LYS A O   1 
ATOM   841   C CB  . LYS A 1 120 ? 18.999  -8.544  -1.268   1.00 21.89  ? 113  LYS A CB  1 
ATOM   842   C CG  . LYS A 1 120 ? 18.794  -9.181  0.084    1.00 20.94  ? 113  LYS A CG  1 
ATOM   843   C CD  . LYS A 1 120 ? 17.441  -9.806  0.226    1.00 22.08  ? 113  LYS A CD  1 
ATOM   844   C CE  . LYS A 1 120 ? 17.412  -11.290 -0.056   1.00 22.20  ? 113  LYS A CE  1 
ATOM   845   N NZ  . LYS A 1 120 ? 16.026  -11.793 0.104    1.00 22.94  ? 113  LYS A NZ  1 
ATOM   846   N N   . GLN A 1 121 ? 19.444  -6.878  -3.623   1.00 24.45  ? 114  GLN A N   1 
ATOM   847   C CA  . GLN A 1 121 ? 19.572  -6.781  -5.108   1.00 23.89  ? 114  GLN A CA  1 
ATOM   848   C C   . GLN A 1 121 ? 18.430  -5.946  -5.673   1.00 21.18  ? 114  GLN A C   1 
ATOM   849   O O   . GLN A 1 121 ? 17.323  -6.458  -5.797   1.00 19.46  ? 114  GLN A O   1 
ATOM   850   C CB  . GLN A 1 121 ? 19.583  -8.176  -5.735   1.00 27.18  ? 114  GLN A CB  1 
ATOM   851   C CG  . GLN A 1 121 ? 20.378  -8.208  -7.035   1.00 31.89  ? 114  GLN A CG  1 
ATOM   852   C CD  . GLN A 1 121 ? 20.097  -9.420  -7.884   1.00 37.73  ? 114  GLN A CD  1 
ATOM   853   O OE1 . GLN A 1 121 ? 19.187  -10.206 -7.610   1.00 46.89  ? 114  GLN A OE1 1 
ATOM   854   N NE2 . GLN A 1 121 ? 20.860  -9.566  -8.957   1.00 40.43  ? 114  GLN A NE2 1 
ATOM   855   N N   . PRO A 1 122 ? 18.634  -4.642  -5.989   1.00 18.83  ? 115  PRO A N   1 
ATOM   856   C CA  . PRO A 1 122 ? 17.558  -3.795  -6.502   1.00 18.89  ? 115  PRO A CA  1 
ATOM   857   C C   . PRO A 1 122 ? 17.217  -4.077  -7.977   1.00 20.10  ? 115  PRO A C   1 
ATOM   858   O O   . PRO A 1 122 ? 16.023  -4.135  -8.302   1.00 21.72  ? 115  PRO A O   1 
ATOM   859   C CB  . PRO A 1 122 ? 18.092  -2.367  -6.308   1.00 17.79  ? 115  PRO A CB  1 
ATOM   860   C CG  . PRO A 1 122 ? 19.576  -2.510  -6.369   1.00 17.08  ? 115  PRO A CG  1 
ATOM   861   C CD  . PRO A 1 122 ? 19.868  -3.880  -5.798   1.00 17.50  ? 115  PRO A CD  1 
ATOM   862   N N   . LEU A 1 123 ? 18.234  -4.232  -8.837   1.00 20.67  ? 116  LEU A N   1 
ATOM   863   C CA  . LEU A 1 123 ? 18.053  -4.652  -10.252  1.00 20.59  ? 116  LEU A CA  1 
ATOM   864   C C   . LEU A 1 123 ? 18.742  -5.989  -10.497  1.00 21.75  ? 116  LEU A C   1 
ATOM   865   O O   . LEU A 1 123 ? 19.769  -6.251  -9.858   1.00 28.49  ? 116  LEU A O   1 
ATOM   866   C CB  . LEU A 1 123 ? 18.592  -3.566  -11.176  1.00 21.02  ? 116  LEU A CB  1 
ATOM   867   C CG  . LEU A 1 123 ? 17.851  -2.233  -11.121  1.00 22.07  ? 116  LEU A CG  1 
ATOM   868   C CD1 . LEU A 1 123 ? 18.322  -1.302  -12.216  1.00 23.55  ? 116  LEU A CD1 1 
ATOM   869   C CD2 . LEU A 1 123 ? 16.356  -2.440  -11.253  1.00 22.94  ? 116  LEU A CD2 1 
ATOM   870   N N   . HIS A 1 124 ? 18.181  -6.781  -11.399  1.00 23.88  ? 117  HIS A N   1 
ATOM   871   C CA  . HIS A 1 124 ? 18.559  -8.187  -11.699  1.00 26.87  ? 117  HIS A CA  1 
ATOM   872   C C   . HIS A 1 124 ? 19.496  -8.227  -12.918  1.00 27.75  ? 117  HIS A C   1 
ATOM   873   O O   . HIS A 1 124 ? 19.645  -7.183  -13.622  1.00 30.09  ? 117  HIS A O   1 
ATOM   874   C CB  . HIS A 1 124 ? 17.292  -9.055  -11.880  1.00 28.28  ? 117  HIS A CB  1 
ATOM   875   C CG  . HIS A 1 124 ? 16.418  -8.636  -13.017  1.00 29.97  ? 117  HIS A CG  1 
ATOM   876   N ND1 . HIS A 1 124 ? 15.869  -7.371  -13.090  1.00 31.68  ? 117  HIS A ND1 1 
ATOM   877   C CD2 . HIS A 1 124 ? 16.023  -9.279  -14.135  1.00 32.73  ? 117  HIS A CD2 1 
ATOM   878   C CE1 . HIS A 1 124 ? 15.165  -7.250  -14.200  1.00 32.29  ? 117  HIS A CE1 1 
ATOM   879   N NE2 . HIS A 1 124 ? 15.252  -8.407  -14.867  1.00 33.72  ? 117  HIS A NE2 1 
ATOM   880   N N   . SER A 1 125 ? 20.094  -9.397  -13.163  1.00 30.25  ? 118  SER A N   1 
ATOM   881   C CA  . SER A 1 125 ? 21.102  -9.665  -14.225  1.00 34.43  ? 118  SER A CA  1 
ATOM   882   C C   . SER A 1 125 ? 20.404  -9.858  -15.569  1.00 35.66  ? 118  SER A C   1 
ATOM   883   O O   . SER A 1 125 ? 20.995  -9.536  -16.590  1.00 36.31  ? 118  SER A O   1 
ATOM   884   C CB  . SER A 1 125 ? 21.907  -10.884 -13.873  1.00 35.85  ? 118  SER A CB  1 
ATOM   885   O OG  . SER A 1 125 ? 21.052  -12.019 -13.752  1.00 36.72  ? 118  SER A OG  1 
ATOM   886   N N   . GLN A 1 126 ? 19.196  -10.414 -15.524  1.00 42.35  ? 119  GLN A N   1 
ATOM   887   C CA  . GLN A 1 126 ? 18.399  -10.896 -16.684  1.00 44.54  ? 119  GLN A CA  1 
ATOM   888   C C   . GLN A 1 126 ? 18.981  -12.207 -17.230  1.00 42.11  ? 119  GLN A C   1 
ATOM   889   O O   . GLN A 1 126 ? 18.595  -12.582 -18.342  1.00 53.46  ? 119  GLN A O   1 
ATOM   890   C CB  . GLN A 1 126 ? 18.341  -9.851  -17.799  1.00 46.49  ? 119  GLN A CB  1 
ATOM   891   C CG  . GLN A 1 126 ? 17.457  -8.659  -17.483  1.00 48.44  ? 119  GLN A CG  1 
ATOM   892   C CD  . GLN A 1 126 ? 18.112  -7.409  -18.003  1.00 50.75  ? 119  GLN A CD  1 
ATOM   893   O OE1 . GLN A 1 126 ? 18.695  -6.646  -17.229  1.00 52.70  ? 119  GLN A OE1 1 
ATOM   894   N NE2 . GLN A 1 126 ? 18.063  -7.232  -19.320  1.00 49.12  ? 119  GLN A NE2 1 
ATOM   895   N N   . GLU A 1 127 ? 19.825  -12.911 -16.484  1.00 36.72  ? 120  GLU A N   1 
ATOM   896   C CA  . GLU A 1 127 ? 20.297  -14.252 -16.907  1.00 36.51  ? 120  GLU A CA  1 
ATOM   897   C C   . GLU A 1 127 ? 19.921  -15.277 -15.838  1.00 35.73  ? 120  GLU A C   1 
ATOM   898   O O   . GLU A 1 127 ? 19.354  -16.300 -16.208  1.00 34.59  ? 120  GLU A O   1 
ATOM   899   C CB  . GLU A 1 127 ? 21.802  -14.261 -17.175  1.00 40.21  ? 120  GLU A CB  1 
ATOM   900   C CG  . GLU A 1 127 ? 22.279  -15.493 -17.925  1.00 39.14  ? 120  GLU A CG  1 
ATOM   901   C CD  . GLU A 1 127 ? 21.855  -15.577 -19.384  1.00 42.48  ? 120  GLU A CD  1 
ATOM   902   O OE1 . GLU A 1 127 ? 21.360  -14.564 -19.940  1.00 41.59  ? 120  GLU A OE1 1 
ATOM   903   O OE2 . GLU A 1 127 ? 22.034  -16.661 -19.978  1.00 48.73  ? 120  GLU A OE2 1 
ATOM   904   N N   . LEU A 1 128 ? 20.259  -15.032 -14.570  1.00 34.77  ? 121  LEU A N   1 
ATOM   905   C CA  . LEU A 1 128 ? 19.854  -15.930 -13.455  1.00 35.53  ? 121  LEU A CA  1 
ATOM   906   C C   . LEU A 1 128 ? 18.354  -15.759 -13.216  1.00 37.01  ? 121  LEU A C   1 
ATOM   907   O O   . LEU A 1 128 ? 17.844  -14.632 -13.440  1.00 42.01  ? 121  LEU A O   1 
ATOM   908   C CB  . LEU A 1 128 ? 20.650  -15.606 -12.189  1.00 35.23  ? 121  LEU A CB  1 
ATOM   909   C CG  . LEU A 1 128 ? 21.982  -16.344 -12.053  1.00 34.65  ? 121  LEU A CG  1 
ATOM   910   C CD1 . LEU A 1 128 ? 22.921  -15.952 -13.173  1.00 39.13  ? 121  LEU A CD1 1 
ATOM   911   C CD2 . LEU A 1 128 ? 22.640  -16.090 -10.709  1.00 32.02  ? 121  LEU A CD2 1 
ATOM   912   N N   . LEU A 1 129 ? 17.667  -16.838 -12.832  1.00 32.48  ? 122  LEU A N   1 
ATOM   913   C CA  . LEU A 1 129 ? 16.216  -16.794 -12.526  1.00 29.40  ? 122  LEU A CA  1 
ATOM   914   C C   . LEU A 1 129 ? 16.047  -15.815 -11.363  1.00 27.07  ? 122  LEU A C   1 
ATOM   915   O O   . LEU A 1 129 ? 16.678  -16.039 -10.360  1.00 27.81  ? 122  LEU A O   1 
ATOM   916   C CB  . LEU A 1 129 ? 15.710  -18.191 -12.148  1.00 30.71  ? 122  LEU A CB  1 
ATOM   917   C CG  . LEU A 1 129 ? 15.995  -19.335 -13.125  1.00 31.05  ? 122  LEU A CG  1 
ATOM   918   C CD1 . LEU A 1 129 ? 15.386  -20.641 -12.635  1.00 30.41  ? 122  LEU A CD1 1 
ATOM   919   C CD2 . LEU A 1 129 ? 15.451  -19.022 -14.500  1.00 32.99  ? 122  LEU A CD2 1 
ATOM   920   N N   . ASP A 1 130 ? 15.280  -14.738 -11.512  1.00 26.56  ? 123  ASP A N   1 
ATOM   921   C CA  . ASP A 1 130 ? 15.039  -13.772 -10.410  1.00 26.17  ? 123  ASP A CA  1 
ATOM   922   C C   . ASP A 1 130 ? 13.773  -14.200 -9.673   1.00 26.76  ? 123  ASP A C   1 
ATOM   923   O O   . ASP A 1 130 ? 12.695  -14.303 -10.255  1.00 28.58  ? 123  ASP A O   1 
ATOM   924   C CB  . ASP A 1 130 ? 15.016  -12.320 -10.884  1.00 27.27  ? 123  ASP A CB  1 
ATOM   925   C CG  . ASP A 1 130 ? 14.178  -12.046 -12.115  1.00 29.58  ? 123  ASP A CG  1 
ATOM   926   O OD1 . ASP A 1 130 ? 14.118  -12.918 -13.011  1.00 30.79  ? 123  ASP A OD1 1 
ATOM   927   O OD2 . ASP A 1 130 ? 13.608  -10.946 -12.179  1.00 32.95  ? 123  ASP A OD2 1 
ATOM   928   N N   . PRO A 1 131 ? 13.875  -14.464 -8.356   1.00 26.94  ? 124  PRO A N   1 
ATOM   929   C CA  . PRO A 1 131 ? 12.822  -15.174 -7.627   1.00 25.09  ? 124  PRO A CA  1 
ATOM   930   C C   . PRO A 1 131 ? 11.564  -14.356 -7.341   1.00 21.97  ? 124  PRO A C   1 
ATOM   931   O O   . PRO A 1 131 ? 10.525  -14.960 -7.296   1.00 23.34  ? 124  PRO A O   1 
ATOM   932   C CB  . PRO A 1 131 ? 13.509  -15.529 -6.307   1.00 27.60  ? 124  PRO A CB  1 
ATOM   933   C CG  . PRO A 1 131 ? 14.530  -14.406 -6.112   1.00 27.92  ? 124  PRO A CG  1 
ATOM   934   C CD  . PRO A 1 131 ? 15.018  -14.087 -7.504   1.00 26.65  ? 124  PRO A CD  1 
ATOM   935   N N   . LEU A 1 132 ? 11.659  -13.036 -7.188   1.00 20.11  ? 125  LEU A N   1 
ATOM   936   C CA  . LEU A 1 132 ? 10.459  -12.185 -6.955   1.00 19.88  ? 125  LEU A CA  1 
ATOM   937   C C   . LEU A 1 132 ? 9.580   -12.158 -8.204   1.00 20.91  ? 125  LEU A C   1 
ATOM   938   O O   . LEU A 1 132 ? 8.382   -12.026 -8.026   1.00 20.51  ? 125  LEU A O   1 
ATOM   939   C CB  . LEU A 1 132 ? 10.857  -10.769 -6.557   1.00 19.48  ? 125  LEU A CB  1 
ATOM   940   C CG  . LEU A 1 132 ? 11.663  -10.673 -5.272   1.00 20.08  ? 125  LEU A CG  1 
ATOM   941   C CD1 . LEU A 1 132 ? 11.784  -9.223  -4.842   1.00 20.67  ? 125  LEU A CD1 1 
ATOM   942   C CD2 . LEU A 1 132 ? 11.034  -11.527 -4.185   1.00 19.77  ? 125  LEU A CD2 1 
ATOM   943   N N   . ARG A 1 133 ? 10.158  -12.234 -9.412   1.00 23.67  ? 126  ARG A N   1 
ATOM   944   C CA  . ARG A 1 133 ? 9.398   -12.326 -10.692  1.00 22.67  ? 126  ARG A CA  1 
ATOM   945   C C   . ARG A 1 133 ? 8.468   -13.533 -10.595  1.00 22.73  ? 126  ARG A C   1 
ATOM   946   O O   . ARG A 1 133 ? 7.257   -13.347 -10.716  1.00 20.59  ? 126  ARG A O   1 
ATOM   947   C CB  . ARG A 1 133 ? 10.339  -12.454 -11.891  1.00 24.02  ? 126  ARG A CB  1 
ATOM   948   C CG  . ARG A 1 133 ? 9.644   -12.622 -13.237  1.00 24.45  ? 126  ARG A CG  1 
ATOM   949   C CD  . ARG A 1 133 ? 10.605  -12.851 -14.403  1.00 24.90  ? 126  ARG A CD  1 
ATOM   950   N NE  . ARG A 1 133 ? 11.678  -11.871 -14.368  1.00 24.98  ? 126  ARG A NE  1 
ATOM   951   C CZ  . ARG A 1 133 ? 11.629  -10.657 -14.909  1.00 25.13  ? 126  ARG A CZ  1 
ATOM   952   N NH1 . ARG A 1 133 ? 10.578  -10.250 -15.602  1.00 23.52  ? 126  ARG A NH1 1 
ATOM   953   N NH2 . ARG A 1 133 ? 12.657  -9.847  -14.754  1.00 25.12  ? 126  ARG A NH2 1 
ATOM   954   N N   . ALA A 1 134 ? 9.038   -14.705 -10.332  1.00 23.49  ? 127  ALA A N   1 
ATOM   955   C CA  . ALA A 1 134 ? 8.331   -15.995 -10.159  1.00 24.15  ? 127  ALA A CA  1 
ATOM   956   C C   . ALA A 1 134 ? 7.241   -15.863 -9.086   1.00 24.38  ? 127  ALA A C   1 
ATOM   957   O O   . ALA A 1 134 ? 6.109   -16.326 -9.322   1.00 20.30  ? 127  ALA A O   1 
ATOM   958   C CB  . ALA A 1 134 ? 9.345   -17.054 -9.787   1.00 24.47  ? 127  ALA A CB  1 
ATOM   959   N N   . MET A 1 135 ? 7.577   -15.260 -7.941   1.00 25.23  ? 128  MET A N   1 
ATOM   960   C CA  . MET A 1 135 ? 6.641   -15.097 -6.798   1.00 27.18  ? 128  MET A CA  1 
ATOM   961   C C   . MET A 1 135 ? 5.499   -14.144 -7.182   1.00 24.75  ? 128  MET A C   1 
ATOM   962   O O   . MET A 1 135 ? 4.332   -14.472 -6.887   1.00 23.75  ? 128  MET A O   1 
ATOM   963   C CB  . MET A 1 135 ? 7.359   -14.571 -5.548   1.00 30.82  ? 128  MET A CB  1 
ATOM   964   C CG  . MET A 1 135 ? 8.377   -15.546 -4.950   1.00 32.77  ? 128  MET A CG  1 
ATOM   965   S SD  . MET A 1 135 ? 7.611   -17.041 -4.288   1.00 41.95  ? 128  MET A SD  1 
ATOM   966   C CE  . MET A 1 135 ? 9.057   -17.950 -3.764   1.00 42.35  ? 128  MET A CE  1 
ATOM   967   N N   . LEU A 1 136 ? 5.792   -13.013 -7.819   1.00 22.05  ? 129  LEU A N   1 
ATOM   968   C CA  . LEU A 1 136 ? 4.744   -12.019 -8.153   1.00 20.44  ? 129  LEU A CA  1 
ATOM   969   C C   . LEU A 1 136 ? 3.858   -12.604 -9.251   1.00 20.45  ? 129  LEU A C   1 
ATOM   970   O O   . LEU A 1 136 ? 2.650   -12.353 -9.234   1.00 19.10  ? 129  LEU A O   1 
ATOM   971   C CB  . LEU A 1 136 ? 5.381   -10.705 -8.598   1.00 20.66  ? 129  LEU A CB  1 
ATOM   972   C CG  . LEU A 1 136 ? 4.391   -9.674  -9.132   1.00 20.98  ? 129  LEU A CG  1 
ATOM   973   C CD1 . LEU A 1 136 ? 3.413   -9.261  -8.062   1.00 19.17  ? 129  LEU A CD1 1 
ATOM   974   C CD2 . LEU A 1 136 ? 5.101   -8.456  -9.699   1.00 22.11  ? 129  LEU A CD2 1 
ATOM   975   N N   . ALA A 1 137 ? 4.435   -13.365 -10.174  1.00 19.64  ? 130  ALA A N   1 
ATOM   976   C CA  . ALA A 1 137 ? 3.689   -14.007 -11.278  1.00 19.93  ? 130  ALA A CA  1 
ATOM   977   C C   . ALA A 1 137 ? 2.727   -15.030 -10.678  1.00 18.65  ? 130  ALA A C   1 
ATOM   978   O O   . ALA A 1 137 ? 1.582   -15.063 -11.120  1.00 17.63  ? 130  ALA A O   1 
ATOM   979   C CB  . ALA A 1 137 ? 4.633   -14.639 -12.290  1.00 19.85  ? 130  ALA A CB  1 
ATOM   980   N N   . LYS A 1 138 ? 3.195   -15.846 -9.736   1.00 18.18  ? 131  LYS A N   1 
ATOM   981   C CA  . LYS A 1 138 ? 2.366   -16.863 -9.042   1.00 19.83  ? 131  LYS A CA  1 
ATOM   982   C C   . LYS A 1 138 ? 1.232   -16.138 -8.334   1.00 18.56  ? 131  LYS A C   1 
ATOM   983   O O   . LYS A 1 138 ? 0.074   -16.555 -8.459   1.00 19.06  ? 131  LYS A O   1 
ATOM   984   C CB  . LYS A 1 138 ? 3.232   -17.642 -8.052   1.00 24.50  ? 131  LYS A CB  1 
ATOM   985   C CG  . LYS A 1 138 ? 2.501   -18.528 -7.051   1.00 27.92  ? 131  LYS A CG  1 
ATOM   986   C CD  . LYS A 1 138 ? 1.717   -19.650 -7.688   1.00 30.95  ? 131  LYS A CD  1 
ATOM   987   C CE  . LYS A 1 138 ? 1.265   -20.680 -6.673   1.00 33.97  ? 131  LYS A CE  1 
ATOM   988   N NZ  . LYS A 1 138 ? 0.080   -21.415 -7.165   1.00 36.72  ? 131  LYS A NZ  1 
ATOM   989   N N   . THR A 1 139 ? 1.577   -15.082 -7.612   1.00 17.56  ? 132  THR A N   1 
ATOM   990   C CA  . THR A 1 139 ? 0.634   -14.234 -6.847   1.00 16.75  ? 132  THR A CA  1 
ATOM   991   C C   . THR A 1 139 ? -0.407  -13.675 -7.811   1.00 16.15  ? 132  THR A C   1 
ATOM   992   O O   . THR A 1 139 ? -1.591  -13.872 -7.558   1.00 16.29  ? 132  THR A O   1 
ATOM   993   C CB  . THR A 1 139 ? 1.397   -13.161 -6.058   1.00 16.82  ? 132  THR A CB  1 
ATOM   994   O OG1 . THR A 1 139 ? 2.321   -13.838 -5.206   1.00 16.35  ? 132  THR A OG1 1 
ATOM   995   C CG2 . THR A 1 139 ? 0.505   -12.266 -5.227   1.00 17.60  ? 132  THR A CG2 1 
ATOM   996   N N   . LEU A 1 140 ? 0.012   -13.036 -8.888   1.00 17.40  ? 133  LEU A N   1 
ATOM   997   C CA  . LEU A 1 140 ? -0.921  -12.403 -9.853   1.00 19.54  ? 133  LEU A CA  1 
ATOM   998   C C   . LEU A 1 140 ? -1.812  -13.470 -10.502  1.00 20.47  ? 133  LEU A C   1 
ATOM   999   O O   . LEU A 1 140 ? -2.988  -13.169 -10.728  1.00 20.36  ? 133  LEU A O   1 
ATOM   1000  C CB  . LEU A 1 140 ? -0.146  -11.575 -10.884  1.00 19.42  ? 133  LEU A CB  1 
ATOM   1001  C CG  . LEU A 1 140 ? 0.251   -10.180 -10.398  1.00 20.27  ? 133  LEU A CG  1 
ATOM   1002  C CD1 . LEU A 1 140 ? 1.035   -9.431  -11.437  1.00 21.94  ? 133  LEU A CD1 1 
ATOM   1003  C CD2 . LEU A 1 140 ? -0.972  -9.367  -10.048  1.00 22.34  ? 133  LEU A CD2 1 
ATOM   1004  N N   . ALA A 1 141 ? -1.311  -14.683 -10.733  1.00 21.13  ? 134  ALA A N   1 
ATOM   1005  C CA  . ALA A 1 141 ? -2.114  -15.802 -11.286  1.00 21.88  ? 134  ALA A CA  1 
ATOM   1006  C C   . ALA A 1 141 ? -3.242  -16.173 -10.313  1.00 22.42  ? 134  ALA A C   1 
ATOM   1007  O O   . ALA A 1 141 ? -4.391  -16.299 -10.749  1.00 24.80  ? 134  ALA A O   1 
ATOM   1008  C CB  . ALA A 1 141 ? -1.221  -16.976 -11.588  1.00 22.32  ? 134  ALA A CB  1 
ATOM   1009  N N   . ALA A 1 142 ? -2.926  -16.323 -9.029   1.00 24.42  ? 135  ALA A N   1 
ATOM   1010  C CA  . ALA A 1 142 ? -3.904  -16.622 -7.951   1.00 24.65  ? 135  ALA A CA  1 
ATOM   1011  C C   . ALA A 1 142 ? -4.892  -15.460 -7.784   1.00 25.37  ? 135  ALA A C   1 
ATOM   1012  O O   . ALA A 1 142 ? -6.092  -15.729 -7.523   1.00 28.56  ? 135  ALA A O   1 
ATOM   1013  C CB  . ALA A 1 142 ? -3.177  -16.907 -6.662   1.00 25.20  ? 135  ALA A CB  1 
ATOM   1014  N N   . LEU A 1 143 ? -4.427  -14.219 -7.927   1.00 25.26  ? 136  LEU A N   1 
ATOM   1015  C CA  . LEU A 1 143 ? -5.257  -13.011 -7.700   1.00 27.26  ? 136  LEU A CA  1 
ATOM   1016  C C   . LEU A 1 143 ? -6.218  -12.799 -8.870   1.00 27.25  ? 136  LEU A C   1 
ATOM   1017  O O   . LEU A 1 143 ? -7.288  -12.228 -8.643   1.00 27.91  ? 136  LEU A O   1 
ATOM   1018  C CB  . LEU A 1 143 ? -4.342  -11.798 -7.532   1.00 28.57  ? 136  LEU A CB  1 
ATOM   1019  C CG  . LEU A 1 143 ? -5.053  -10.507 -7.128   1.00 30.17  ? 136  LEU A CG  1 
ATOM   1020  C CD1 . LEU A 1 143 ? -5.781  -10.670 -5.805   1.00 29.93  ? 136  LEU A CD1 1 
ATOM   1021  C CD2 . LEU A 1 143 ? -4.063  -9.354  -7.035   1.00 29.49  ? 136  LEU A CD2 1 
ATOM   1022  N N   . THR A 1 144 ? -5.840  -13.209 -10.079  1.00 26.69  ? 137  THR A N   1 
ATOM   1023  C CA  . THR A 1 144 ? -6.614  -12.919 -11.310  1.00 26.18  ? 137  THR A CA  1 
ATOM   1024  C C   . THR A 1 144 ? -7.652  -13.996 -11.568  1.00 27.29  ? 137  THR A C   1 
ATOM   1025  O O   . THR A 1 144 ? -7.472  -15.158 -11.199  1.00 24.87  ? 137  THR A O   1 
ATOM   1026  C CB  . THR A 1 144 ? -5.748  -12.802 -12.569  1.00 24.62  ? 137  THR A CB  1 
ATOM   1027  O OG1 . THR A 1 144 ? -4.938  -13.973 -12.661  1.00 23.26  ? 137  THR A OG1 1 
ATOM   1028  C CG2 . THR A 1 144 ? -4.949  -11.521 -12.573  1.00 23.69  ? 137  THR A CG2 1 
ATOM   1029  N N   . PRO A 1 145 ? -8.740  -13.611 -12.268  1.00 32.05  ? 138  PRO A N   1 
ATOM   1030  C CA  . PRO A 1 145 ? -9.825  -14.529 -12.589  1.00 34.22  ? 138  PRO A CA  1 
ATOM   1031  C C   . PRO A 1 145 ? -9.445  -15.589 -13.626  1.00 35.10  ? 138  PRO A C   1 
ATOM   1032  O O   . PRO A 1 145 ? -8.693  -15.295 -14.525  1.00 37.09  ? 138  PRO A O   1 
ATOM   1033  C CB  . PRO A 1 145 ? -10.949 -13.632 -13.143  1.00 33.92  ? 138  PRO A CB  1 
ATOM   1034  C CG  . PRO A 1 145 ? -10.259 -12.365 -13.585  1.00 32.86  ? 138  PRO A CG  1 
ATOM   1035  C CD  . PRO A 1 145 ? -9.022  -12.238 -12.720  1.00 33.55  ? 138  PRO A CD  1 
ATOM   1036  N N   . GLY A 1 146 ? -9.997  -16.790 -13.432  1.00 39.77  ? 139  GLY A N   1 
ATOM   1037  C CA  . GLY A 1 146 ? -10.101 -17.865 -14.432  1.00 40.82  ? 139  GLY A CA  1 
ATOM   1038  C C   . GLY A 1 146 ? -8.739  -18.284 -14.937  1.00 41.90  ? 139  GLY A C   1 
ATOM   1039  O O   . GLY A 1 146 ? -7.854  -18.628 -14.117  1.00 37.88  ? 139  GLY A O   1 
ATOM   1040  N N   . LYS A 1 147 ? -8.591  -18.240 -16.261  1.00 40.95  ? 140  LYS A N   1 
ATOM   1041  C CA  . LYS A 1 147 ? -7.491  -18.898 -17.002  1.00 42.63  ? 140  LYS A CA  1 
ATOM   1042  C C   . LYS A 1 147 ? -6.363  -17.888 -17.244  1.00 37.56  ? 140  LYS A C   1 
ATOM   1043  O O   . LYS A 1 147 ? -5.391  -18.283 -17.903  1.00 38.22  ? 140  LYS A O   1 
ATOM   1044  C CB  . LYS A 1 147 ? -8.064  -19.542 -18.269  1.00 46.20  ? 140  LYS A CB  1 
ATOM   1045  C CG  . LYS A 1 147 ? -9.108  -20.611 -17.957  1.00 51.70  ? 140  LYS A CG  1 
ATOM   1046  C CD  . LYS A 1 147 ? -9.729  -21.288 -19.142  1.00 58.82  ? 140  LYS A CD  1 
ATOM   1047  C CE  . LYS A 1 147 ? -8.904  -22.462 -19.620  1.00 66.22  ? 140  LYS A CE  1 
ATOM   1048  N NZ  . LYS A 1 147 ? -9.731  -23.439 -20.372  1.00 69.26  ? 140  LYS A NZ  1 
ATOM   1049  N N   . LEU A 1 148 ? -6.465  -16.660 -16.717  1.00 31.63  ? 141  LEU A N   1 
ATOM   1050  C CA  . LEU A 1 148 ? -5.320  -15.706 -16.658  1.00 28.80  ? 141  LEU A CA  1 
ATOM   1051  C C   . LEU A 1 148 ? -4.217  -16.318 -15.788  1.00 28.81  ? 141  LEU A C   1 
ATOM   1052  O O   . LEU A 1 148 ? -4.471  -16.534 -14.562  1.00 34.44  ? 141  LEU A O   1 
ATOM   1053  C CB  . LEU A 1 148 ? -5.775  -14.350 -16.112  1.00 26.74  ? 141  LEU A CB  1 
ATOM   1054  C CG  . LEU A 1 148 ? -6.623  -13.528 -17.082  1.00 27.10  ? 141  LEU A CG  1 
ATOM   1055  C CD1 . LEU A 1 148 ? -7.024  -12.223 -16.426  1.00 27.00  ? 141  LEU A CD1 1 
ATOM   1056  C CD2 . LEU A 1 148 ? -5.892  -13.264 -18.401  1.00 27.09  ? 141  LEU A CD2 1 
ATOM   1057  N N   . LYS A 1 149 ? -3.056  -16.611 -16.381  1.00 23.78  ? 142  LYS A N   1 
ATOM   1058  C CA  . LYS A 1 149 ? -2.040  -17.509 -15.780  1.00 23.18  ? 142  LYS A CA  1 
ATOM   1059  C C   . LYS A 1 149 ? -0.612  -16.977 -15.972  1.00 21.68  ? 142  LYS A C   1 
ATOM   1060  O O   . LYS A 1 149 ? 0.204   -17.203 -15.076  1.00 23.48  ? 142  LYS A O   1 
ATOM   1061  C CB  . LYS A 1 149 ? -2.182  -18.910 -16.378  1.00 23.70  ? 142  LYS A CB  1 
ATOM   1062  C CG  . LYS A 1 149 ? -1.287  -19.979 -15.760  1.00 24.37  ? 142  LYS A CG  1 
ATOM   1063  C CD  . LYS A 1 149 ? -1.732  -21.393 -16.091  1.00 25.50  ? 142  LYS A CD  1 
ATOM   1064  C CE  . LYS A 1 149 ? -0.883  -22.486 -15.477  1.00 26.32  ? 142  LYS A CE  1 
ATOM   1065  N NZ  . LYS A 1 149 ? 0.353   -22.722 -16.266  1.00 29.04  ? 142  LYS A NZ  1 
ATOM   1066  N N   . TYR A 1 150 ? -0.283  -16.350 -17.097  1.00 20.38  ? 143  TYR A N   1 
ATOM   1067  C CA  . TYR A 1 150 ? 1.106   -15.934 -17.394  1.00 19.74  ? 143  TYR A CA  1 
ATOM   1068  C C   . TYR A 1 150 ? 1.185   -14.423 -17.334  1.00 19.44  ? 143  TYR A C   1 
ATOM   1069  O O   . TYR A 1 150 ? 0.234   -13.756 -17.728  1.00 18.22  ? 143  TYR A O   1 
ATOM   1070  C CB  . TYR A 1 150 ? 1.608   -16.502 -18.717  1.00 20.20  ? 143  TYR A CB  1 
ATOM   1071  C CG  . TYR A 1 150 ? 2.011   -17.950 -18.606  1.00 20.71  ? 143  TYR A CG  1 
ATOM   1072  C CD1 . TYR A 1 150 ? 1.074   -18.962 -18.757  1.00 21.58  ? 143  TYR A CD1 1 
ATOM   1073  C CD2 . TYR A 1 150 ? 3.301   -18.317 -18.273  1.00 21.08  ? 143  TYR A CD2 1 
ATOM   1074  C CE1 . TYR A 1 150 ? 1.411   -20.297 -18.625  1.00 21.03  ? 143  TYR A CE1 1 
ATOM   1075  C CE2 . TYR A 1 150 ? 3.655   -19.652 -18.139  1.00 21.66  ? 143  TYR A CE2 1 
ATOM   1076  C CZ  . TYR A 1 150 ? 2.708   -20.647 -18.320  1.00 21.47  ? 143  TYR A CZ  1 
ATOM   1077  O OH  . TYR A 1 150 ? 3.031   -21.968 -18.183  1.00 22.20  ? 143  TYR A OH  1 
ATOM   1078  N N   . SER A 1 151 ? 2.293   -13.948 -16.762  1.00 19.96  ? 144  SER A N   1 
ATOM   1079  C CA  . SER A 1 151 ? 2.573   -12.520 -16.501  1.00 19.90  ? 144  SER A CA  1 
ATOM   1080  C C   . SER A 1 151 ? 3.884   -12.138 -17.181  1.00 20.15  ? 144  SER A C   1 
ATOM   1081  O O   . SER A 1 151 ? 4.872   -12.912 -17.125  1.00 19.58  ? 144  SER A O   1 
ATOM   1082  C CB  . SER A 1 151 ? 2.596   -12.228 -15.033  1.00 20.78  ? 144  SER A CB  1 
ATOM   1083  O OG  . SER A 1 151 ? 1.368   -12.622 -14.428  1.00 21.08  ? 144  SER A OG  1 
ATOM   1084  N N   . PHE A 1 152 ? 3.840   -10.995 -17.849  1.00 19.91  ? 145  PHE A N   1 
ATOM   1085  C CA  . PHE A 1 152 ? 4.999   -10.272 -18.400  1.00 20.20  ? 145  PHE A CA  1 
ATOM   1086  C C   . PHE A 1 152 ? 5.059   -8.916  -17.711  1.00 19.35  ? 145  PHE A C   1 
ATOM   1087  O O   . PHE A 1 152 ? 4.057   -8.207  -17.740  1.00 20.94  ? 145  PHE A O   1 
ATOM   1088  C CB  . PHE A 1 152 ? 4.858   -10.089 -19.911  1.00 21.97  ? 145  PHE A CB  1 
ATOM   1089  C CG  . PHE A 1 152 ? 5.902   -9.168  -20.463  1.00 22.43  ? 145  PHE A CG  1 
ATOM   1090  C CD1 . PHE A 1 152 ? 7.151   -9.657  -20.792  1.00 22.66  ? 145  PHE A CD1 1 
ATOM   1091  C CD2 . PHE A 1 152 ? 5.651   -7.807  -20.566  1.00 23.62  ? 145  PHE A CD2 1 
ATOM   1092  C CE1 . PHE A 1 152 ? 8.138   -8.794  -21.231  1.00 23.55  ? 145  PHE A CE1 1 
ATOM   1093  C CE2 . PHE A 1 152 ? 6.631   -6.949  -21.040  1.00 24.95  ? 145  PHE A CE2 1 
ATOM   1094  C CZ  . PHE A 1 152 ? 7.876   -7.445  -21.357  1.00 24.55  ? 145  PHE A CZ  1 
ATOM   1095  N N   . PHE A 1 153 ? 6.202   -8.586  -17.115  1.00 19.71  ? 146  PHE A N   1 
ATOM   1096  C CA  . PHE A 1 153 ? 6.413   -7.359  -16.311  1.00 18.69  ? 146  PHE A CA  1 
ATOM   1097  C C   . PHE A 1 153 ? 7.185   -6.329  -17.117  1.00 17.13  ? 146  PHE A C   1 
ATOM   1098  O O   . PHE A 1 153 ? 8.167   -6.672  -17.794  1.00 15.95  ? 146  PHE A O   1 
ATOM   1099  C CB  . PHE A 1 153 ? 7.114   -7.721  -15.014  1.00 19.12  ? 146  PHE A CB  1 
ATOM   1100  C CG  . PHE A 1 153 ? 6.320   -8.708  -14.199  1.00 21.72  ? 146  PHE A CG  1 
ATOM   1101  C CD1 . PHE A 1 153 ? 5.091   -8.356  -13.674  1.00 20.44  ? 146  PHE A CD1 1 
ATOM   1102  C CD2 . PHE A 1 153 ? 6.783   -9.998  -13.994  1.00 22.60  ? 146  PHE A CD2 1 
ATOM   1103  C CE1 . PHE A 1 153 ? 4.361   -9.267  -12.935  1.00 22.41  ? 146  PHE A CE1 1 
ATOM   1104  C CE2 . PHE A 1 153 ? 6.058   -10.900 -13.236  1.00 22.59  ? 146  PHE A CE2 1 
ATOM   1105  C CZ  . PHE A 1 153 ? 4.840   -10.536 -12.719  1.00 22.90  ? 146  PHE A CZ  1 
ATOM   1106  N N   . CYS A 1 154 ? 6.709   -5.096  -17.033  1.00 16.25  ? 147  CYS A N   1 
ATOM   1107  C CA  . CYS A 1 154 ? 7.293   -3.921  -17.699  1.00 16.87  ? 147  CYS A CA  1 
ATOM   1108  C C   . CYS A 1 154 ? 7.307   -2.790  -16.672  1.00 15.91  ? 147  CYS A C   1 
ATOM   1109  O O   . CYS A 1 154 ? 7.170   -3.093  -15.467  1.00 14.39  ? 147  CYS A O   1 
ATOM   1110  C CB  . CYS A 1 154 ? 6.510   -3.609  -18.968  1.00 18.14  ? 147  CYS A CB  1 
ATOM   1111  S SG  . CYS A 1 154 ? 4.719   -3.634  -18.734  1.00 21.02  ? 147  CYS A SG  1 
ATOM   1112  N N   . ASN A 1 155 ? 7.447   -1.549  -17.127  1.00 15.83  ? 148  ASN A N   1 
ATOM   1113  C CA  . ASN A 1 155 ? 7.737   -0.393  -16.255  1.00 16.22  ? 148  ASN A CA  1 
ATOM   1114  C C   . ASN A 1 155 ? 6.625   0.655   -16.306  1.00 15.69  ? 148  ASN A C   1 
ATOM   1115  O O   . ASN A 1 155 ? 6.757   1.635   -15.546  1.00 14.87  ? 148  ASN A O   1 
ATOM   1116  C CB  . ASN A 1 155 ? 9.073   0.229   -16.639  1.00 18.52  ? 148  ASN A CB  1 
ATOM   1117  C CG  . ASN A 1 155 ? 10.201  -0.786  -16.692  1.00 20.56  ? 148  ASN A CG  1 
ATOM   1118  O OD1 . ASN A 1 155 ? 10.585  -1.339  -15.647  1.00 22.92  ? 148  ASN A OD1 1 
ATOM   1119  N ND2 . ASN A 1 155 ? 10.724  -1.028  -17.894  1.00 20.40  ? 148  ASN A ND2 1 
ATOM   1120  N N   . SER A 1 156 ? 5.567   0.482   -17.120  1.00 14.60  ? 149  SER A N   1 
ATOM   1121  C CA  . SER A 1 156 ? 4.506   1.513   -17.236  1.00 14.53  ? 149  SER A CA  1 
ATOM   1122  C C   . SER A 1 156 ? 3.197   0.943   -17.800  1.00 14.66  ? 149  SER A C   1 
ATOM   1123  O O   . SER A 1 156 ? 3.200   -0.188  -18.327  1.00 14.70  ? 149  SER A O   1 
ATOM   1124  C CB  . SER A 1 156 ? 5.008   2.656   -18.060  1.00 14.33  ? 149  SER A CB  1 
ATOM   1125  O OG  . SER A 1 156 ? 5.284   2.222   -19.371  1.00 13.74  ? 149  SER A OG  1 
ATOM   1126  N N   . GLY A 1 157 ? 2.115   1.718   -17.714  1.00 14.78  ? 150  GLY A N   1 
ATOM   1127  C CA  . GLY A 1 157 ? 0.830   1.352   -18.332  1.00 15.15  ? 150  GLY A CA  1 
ATOM   1128  C C   . GLY A 1 157 ? 1.002   1.182   -19.821  1.00 16.32  ? 150  GLY A C   1 
ATOM   1129  O O   . GLY A 1 157 ? 0.597   0.139   -20.376  1.00 19.42  ? 150  GLY A O   1 
ATOM   1130  N N   . THR A 1 158 ? 1.631   2.159   -20.471  1.00 15.82  ? 151  THR A N   1 
ATOM   1131  C CA  . THR A 1 158 ? 1.794   2.168   -21.941  1.00 14.93  ? 151  THR A CA  1 
ATOM   1132  C C   . THR A 1 158 ? 2.591   0.930   -22.357  1.00 14.25  ? 151  THR A C   1 
ATOM   1133  O O   . THR A 1 158 ? 2.218   0.320   -23.360  1.00 12.56  ? 151  THR A O   1 
ATOM   1134  C CB  . THR A 1 158 ? 2.357   3.509   -22.408  1.00 15.50  ? 151  THR A CB  1 
ATOM   1135  O OG1 . THR A 1 158 ? 2.149   3.576   -23.819  1.00 16.20  ? 151  THR A OG1 1 
ATOM   1136  C CG2 . THR A 1 158 ? 3.815   3.701   -22.076  1.00 15.60  ? 151  THR A CG2 1 
ATOM   1137  N N   . GLU A 1 159 ? 3.597   0.519   -21.583  1.00 14.16  ? 152  GLU A N   1 
ATOM   1138  C CA  . GLU A 1 159 ? 4.392   -0.693  -21.907  1.00 15.00  ? 152  GLU A CA  1 
ATOM   1139  C C   . GLU A 1 159 ? 3.505   -1.929  -21.752  1.00 14.62  ? 152  GLU A C   1 
ATOM   1140  O O   . GLU A 1 159 ? 3.628   -2.840  -22.558  1.00 14.54  ? 152  GLU A O   1 
ATOM   1141  C CB  . GLU A 1 159 ? 5.654   -0.833  -21.055  1.00 16.48  ? 152  GLU A CB  1 
ATOM   1142  C CG  . GLU A 1 159 ? 6.866   -0.080  -21.567  1.00 17.20  ? 152  GLU A CG  1 
ATOM   1143  C CD  . GLU A 1 159 ? 8.183   -0.343  -20.821  1.00 18.52  ? 152  GLU A CD  1 
ATOM   1144  O OE1 . GLU A 1 159 ? 8.164   -0.444  -19.590  1.00 19.48  ? 152  GLU A OE1 1 
ATOM   1145  O OE2 . GLU A 1 159 ? 9.239   -0.439  -21.477  1.00 19.59  ? 152  GLU A OE2 1 
ATOM   1146  N N   A SER A 1 160 ? 2.645   -1.965  -20.732  0.50 15.10  ? 153  SER A N   1 
ATOM   1147  N N   B SER A 1 160 ? 2.644   -1.965  -20.732  0.50 14.82  ? 153  SER A N   1 
ATOM   1148  C CA  A SER A 1 160 ? 1.739   -3.115  -20.471  0.50 15.51  ? 153  SER A CA  1 
ATOM   1149  C CA  B SER A 1 160 ? 1.734   -3.113  -20.468  0.50 15.06  ? 153  SER A CA  1 
ATOM   1150  C C   A SER A 1 160 ? 0.757   -3.264  -21.639  0.50 15.52  ? 153  SER A C   1 
ATOM   1151  C C   B SER A 1 160 ? 0.755   -3.263  -21.638  0.50 15.26  ? 153  SER A C   1 
ATOM   1152  O O   A SER A 1 160 ? 0.455   -4.408  -22.015  0.50 15.17  ? 153  SER A O   1 
ATOM   1153  O O   B SER A 1 160 ? 0.455   -4.408  -22.015  0.50 14.94  ? 153  SER A O   1 
ATOM   1154  C CB  A SER A 1 160 ? 1.012   -2.994  -19.162  0.50 15.82  ? 153  SER A CB  1 
ATOM   1155  C CB  B SER A 1 160 ? 1.016   -2.988  -19.146  0.50 15.06  ? 153  SER A CB  1 
ATOM   1156  O OG  A SER A 1 160 ? 0.037   -4.023  -19.062  0.50 16.02  ? 153  SER A OG  1 
ATOM   1157  O OG  B SER A 1 160 ? -0.139  -2.160  -19.217  0.50 14.60  ? 153  SER A OG  1 
ATOM   1158  N N   . VAL A 1 161 ? 0.309   -2.142  -22.205  1.00 15.76  ? 154  VAL A N   1 
ATOM   1159  C CA  . VAL A 1 161 ? -0.606  -2.124  -23.381  1.00 16.80  ? 154  VAL A CA  1 
ATOM   1160  C C   . VAL A 1 161 ? 0.179   -2.588  -24.623  1.00 17.03  ? 154  VAL A C   1 
ATOM   1161  O O   . VAL A 1 161 ? -0.344  -3.427  -25.378  1.00 15.37  ? 154  VAL A O   1 
ATOM   1162  C CB  . VAL A 1 161 ? -1.269  -0.740  -23.538  1.00 16.72  ? 154  VAL A CB  1 
ATOM   1163  C CG1 . VAL A 1 161 ? -1.865  -0.539  -24.916  1.00 16.16  ? 154  VAL A CG1 1 
ATOM   1164  C CG2 . VAL A 1 161 ? -2.312  -0.504  -22.466  1.00 16.92  ? 154  VAL A CG2 1 
ATOM   1165  N N   . GLU A 1 162 ? 1.410   -2.111  -24.805  1.00 19.44  ? 155  GLU A N   1 
ATOM   1166  C CA  . GLU A 1 162 ? 2.270   -2.528  -25.956  1.00 22.08  ? 155  GLU A CA  1 
ATOM   1167  C C   . GLU A 1 162 ? 2.392   -4.050  -25.924  1.00 21.41  ? 155  GLU A C   1 
ATOM   1168  O O   . GLU A 1 162 ? 2.189   -4.681  -26.964  1.00 21.64  ? 155  GLU A O   1 
ATOM   1169  C CB  . GLU A 1 162 ? 3.664   -1.919  -25.889  1.00 25.11  ? 155  GLU A CB  1 
ATOM   1170  C CG  . GLU A 1 162 ? 3.665   -0.419  -26.080  1.00 27.62  ? 155  GLU A CG  1 
ATOM   1171  C CD  . GLU A 1 162 ? 3.613   0.072   -27.511  1.00 29.31  ? 155  GLU A CD  1 
ATOM   1172  O OE1 . GLU A 1 162 ? 3.929   -0.706  -28.421  1.00 29.59  ? 155  GLU A OE1 1 
ATOM   1173  O OE2 . GLU A 1 162 ? 3.302   1.265   -27.696  1.00 34.73  ? 155  GLU A OE2 1 
ATOM   1174  N N   . ALA A 1 163 ? 2.664   -4.610  -24.742  1.00 19.76  ? 156  ALA A N   1 
ATOM   1175  C CA  . ALA A 1 163 ? 2.821   -6.065  -24.546  1.00 18.28  ? 156  ALA A CA  1 
ATOM   1176  C C   . ALA A 1 163 ? 1.530   -6.785  -24.943  1.00 16.80  ? 156  ALA A C   1 
ATOM   1177  O O   . ALA A 1 163 ? 1.610   -7.830  -25.606  1.00 15.30  ? 156  ALA A O   1 
ATOM   1178  C CB  . ALA A 1 163 ? 3.216   -6.345  -23.127  1.00 18.76  ? 156  ALA A CB  1 
ATOM   1179  N N   . ALA A 1 164 ? 0.381   -6.232  -24.566  1.00 16.14  ? 157  ALA A N   1 
ATOM   1180  C CA  . ALA A 1 164 ? -0.942  -6.826  -24.852  1.00 15.69  ? 157  ALA A CA  1 
ATOM   1181  C C   . ALA A 1 164 ? -1.152  -6.847  -26.371  1.00 16.18  ? 157  ALA A C   1 
ATOM   1182  O O   . ALA A 1 164 ? -1.417  -7.930  -26.951  1.00 15.68  ? 157  ALA A O   1 
ATOM   1183  C CB  . ALA A 1 164 ? -2.005  -6.028  -24.147  1.00 15.40  ? 157  ALA A CB  1 
ATOM   1184  N N   . LEU A 1 165 ? -1.022  -5.678  -26.998  1.00 16.36  ? 158  LEU A N   1 
ATOM   1185  C CA  . LEU A 1 165 ? -1.143  -5.524  -28.460  1.00 16.85  ? 158  LEU A CA  1 
ATOM   1186  C C   . LEU A 1 165 ? -0.227  -6.556  -29.122  1.00 16.21  ? 158  LEU A C   1 
ATOM   1187  O O   . LEU A 1 165 ? -0.666  -7.202  -30.082  1.00 16.41  ? 158  LEU A O   1 
ATOM   1188  C CB  . LEU A 1 165 ? -0.769  -4.090  -28.856  1.00 17.83  ? 158  LEU A CB  1 
ATOM   1189  C CG  . LEU A 1 165 ? -1.740  -2.997  -28.394  1.00 17.50  ? 158  LEU A CG  1 
ATOM   1190  C CD1 . LEU A 1 165 ? -1.226  -1.596  -28.732  1.00 17.25  ? 158  LEU A CD1 1 
ATOM   1191  C CD2 . LEU A 1 165 ? -3.119  -3.209  -29.012  1.00 17.43  ? 158  LEU A CD2 1 
ATOM   1192  N N   . LYS A 1 166 ? 0.982   -6.725  -28.597  1.00 14.95  ? 159  LYS A N   1 
ATOM   1193  C CA  . LYS A 1 166 ? 1.984   -7.632  -29.196  1.00 15.18  ? 159  LYS A CA  1 
ATOM   1194  C C   . LYS A 1 166 ? 1.538   -9.085  -29.002  1.00 15.14  ? 159  LYS A C   1 
ATOM   1195  O O   . LYS A 1 166 ? 1.602   -9.854  -29.964  1.00 14.37  ? 159  LYS A O   1 
ATOM   1196  C CB  . LYS A 1 166 ? 3.389   -7.326  -28.656  1.00 15.69  ? 159  LYS A CB  1 
ATOM   1197  C CG  . LYS A 1 166 ? 4.049   -6.104  -29.298  1.00 16.18  ? 159  LYS A CG  1 
ATOM   1198  C CD  . LYS A 1 166 ? 5.509   -5.837  -28.930  1.00 16.87  ? 159  LYS A CD  1 
ATOM   1199  C CE  . LYS A 1 166 ? 6.474   -6.837  -29.543  1.00 17.36  ? 159  LYS A CE  1 
ATOM   1200  N NZ  . LYS A 1 166 ? 7.877   -6.706  -29.071  1.00 16.91  ? 159  LYS A NZ  1 
ATOM   1201  N N   . LEU A 1 167 ? 1.069   -9.465  -27.820  1.00 16.68  ? 160  LEU A N   1 
ATOM   1202  C CA  . LEU A 1 167 ? 0.549   -10.842 -27.586  1.00 16.96  ? 160  LEU A CA  1 
ATOM   1203  C C   . LEU A 1 167 ? -0.542  -11.122 -28.615  1.00 16.33  ? 160  LEU A C   1 
ATOM   1204  O O   . LEU A 1 167 ? -0.493  -12.171 -29.282  1.00 16.51  ? 160  LEU A O   1 
ATOM   1205  C CB  . LEU A 1 167 ? 0.030   -10.976 -26.150  1.00 17.05  ? 160  LEU A CB  1 
ATOM   1206  C CG  . LEU A 1 167 ? 1.121   -11.053 -25.087  1.00 17.73  ? 160  LEU A CG  1 
ATOM   1207  C CD1 . LEU A 1 167 ? 0.511   -10.962 -23.710  1.00 18.53  ? 160  LEU A CD1 1 
ATOM   1208  C CD2 . LEU A 1 167 ? 1.944   -12.321 -25.204  1.00 17.63  ? 160  LEU A CD2 1 
ATOM   1209  N N   . ALA A 1 168 ? -1.455  -10.179 -28.792  1.00 17.00  ? 161  ALA A N   1 
ATOM   1210  C CA  . ALA A 1 168 ? -2.594  -10.336 -29.728  1.00 17.88  ? 161  ALA A CA  1 
ATOM   1211  C C   . ALA A 1 168 ? -2.063  -10.522 -31.158  1.00 17.58  ? 161  ALA A C   1 
ATOM   1212  O O   . ALA A 1 168 ? -2.520  -11.455 -31.870  1.00 16.83  ? 161  ALA A O   1 
ATOM   1213  C CB  . ALA A 1 168 ? -3.516  -9.145  -29.620  1.00 18.41  ? 161  ALA A CB  1 
ATOM   1214  N N   . LYS A 1 169 ? -1.124  -9.662  -31.556  1.00 17.26  ? 162  LYS A N   1 
ATOM   1215  C CA  . LYS A 1 169 ? -0.539  -9.668  -32.917  1.00 15.99  ? 162  LYS A CA  1 
ATOM   1216  C C   . LYS A 1 169 ? 0.083   -11.042 -33.169  1.00 15.61  ? 162  LYS A C   1 
ATOM   1217  O O   . LYS A 1 169 ? -0.168  -11.615 -34.216  1.00 15.97  ? 162  LYS A O   1 
ATOM   1218  C CB  . LYS A 1 169 ? 0.449   -8.513  -33.074  1.00 15.64  ? 162  LYS A CB  1 
ATOM   1219  C CG  . LYS A 1 169 ? -0.191  -7.142  -33.263  1.00 15.90  ? 162  LYS A CG  1 
ATOM   1220  C CD  . LYS A 1 169 ? 0.807   -6.029  -33.520  1.00 16.10  ? 162  LYS A CD  1 
ATOM   1221  C CE  . LYS A 1 169 ? 0.257   -4.820  -34.257  1.00 15.18  ? 162  LYS A CE  1 
ATOM   1222  N NZ  . LYS A 1 169 ? 0.209   -5.000  -35.715  1.00 14.42  ? 162  LYS A NZ  1 
ATOM   1223  N N   . ALA A 1 170 ? 0.837   -11.568 -32.215  1.00 16.36  ? 163  ALA A N   1 
ATOM   1224  C CA  . ALA A 1 170 ? 1.590   -12.835 -32.372  1.00 16.41  ? 163  ALA A CA  1 
ATOM   1225  C C   . ALA A 1 170 ? 0.589   -13.996 -32.423  1.00 17.05  ? 163  ALA A C   1 
ATOM   1226  O O   . ALA A 1 170 ? 0.827   -14.966 -33.170  1.00 18.45  ? 163  ALA A O   1 
ATOM   1227  C CB  . ALA A 1 170 ? 2.598   -12.987 -31.258  1.00 15.21  ? 163  ALA A CB  1 
ATOM   1228  N N   . TYR A 1 171 ? -0.494  -13.908 -31.659  1.00 16.42  ? 164  TYR A N   1 
ATOM   1229  C CA  . TYR A 1 171 ? -1.519  -14.971 -31.644  1.00 18.21  ? 164  TYR A CA  1 
ATOM   1230  C C   . TYR A 1 171 ? -2.293  -14.977 -32.964  1.00 18.66  ? 164  TYR A C   1 
ATOM   1231  O O   . TYR A 1 171 ? -2.536  -16.061 -33.510  1.00 18.73  ? 164  TYR A O   1 
ATOM   1232  C CB  . TYR A 1 171 ? -2.496  -14.782 -30.491  1.00 19.82  ? 164  TYR A CB  1 
ATOM   1233  C CG  . TYR A 1 171 ? -3.399  -15.971 -30.293  1.00 20.04  ? 164  TYR A CG  1 
ATOM   1234  C CD1 . TYR A 1 171 ? -2.906  -17.121 -29.696  1.00 20.36  ? 164  TYR A CD1 1 
ATOM   1235  C CD2 . TYR A 1 171 ? -4.719  -15.968 -30.724  1.00 20.41  ? 164  TYR A CD2 1 
ATOM   1236  C CE1 . TYR A 1 171 ? -3.702  -18.236 -29.509  1.00 20.41  ? 164  TYR A CE1 1 
ATOM   1237  C CE2 . TYR A 1 171 ? -5.530  -17.078 -30.539  1.00 20.84  ? 164  TYR A CE2 1 
ATOM   1238  C CZ  . TYR A 1 171 ? -5.022  -18.216 -29.921  1.00 20.35  ? 164  TYR A CZ  1 
ATOM   1239  O OH  . TYR A 1 171 ? -5.791  -19.331 -29.709  1.00 19.60  ? 164  TYR A OH  1 
ATOM   1240  N N   . GLN A 1 172 ? -2.629  -13.796 -33.478  1.00 19.62  ? 165  GLN A N   1 
ATOM   1241  C CA  . GLN A 1 172 ? -3.700  -13.618 -34.495  1.00 20.00  ? 165  GLN A CA  1 
ATOM   1242  C C   . GLN A 1 172 ? -3.157  -13.504 -35.932  1.00 20.72  ? 165  GLN A C   1 
ATOM   1243  O O   . GLN A 1 172 ? -3.920  -13.848 -36.862  1.00 20.73  ? 165  GLN A O   1 
ATOM   1244  C CB  . GLN A 1 172 ? -4.562  -12.404 -34.124  1.00 19.74  ? 165  GLN A CB  1 
ATOM   1245  C CG  . GLN A 1 172 ? -5.447  -12.629 -32.903  1.00 19.28  ? 165  GLN A CG  1 
ATOM   1246  C CD  . GLN A 1 172 ? -6.605  -13.566 -33.155  1.00 18.33  ? 165  GLN A CD  1 
ATOM   1247  O OE1 . GLN A 1 172 ? -6.433  -14.722 -33.527  1.00 18.00  ? 165  GLN A OE1 1 
ATOM   1248  N NE2 . GLN A 1 172 ? -7.802  -13.086 -32.875  1.00 18.03  ? 165  GLN A NE2 1 
ATOM   1249  N N   . SER A 1 173 ? -1.922  -13.036 -36.143  1.00 23.29  ? 166  SER A N   1 
ATOM   1250  C CA  . SER A 1 173 ? -1.341  -12.866 -37.503  1.00 24.37  ? 166  SER A CA  1 
ATOM   1251  C C   . SER A 1 173 ? -1.231  -14.225 -38.204  1.00 23.16  ? 166  SER A C   1 
ATOM   1252  O O   . SER A 1 173 ? -1.663  -14.342 -39.349  1.00 20.89  ? 166  SER A O   1 
ATOM   1253  C CB  . SER A 1 173 ? -0.041  -12.098 -37.485  1.00 27.10  ? 166  SER A CB  1 
ATOM   1254  O OG  . SER A 1 173 ? 1.079   -12.929 -37.217  1.00 30.13  ? 166  SER A OG  1 
ATOM   1255  N N   . PRO A 1 174 ? -0.804  -15.317 -37.518  1.00 21.88  ? 167  PRO A N   1 
ATOM   1256  C CA  . PRO A 1 174 ? -0.817  -16.649 -38.109  1.00 22.56  ? 167  PRO A CA  1 
ATOM   1257  C C   . PRO A 1 174 ? -2.248  -17.136 -38.374  1.00 25.24  ? 167  PRO A C   1 
ATOM   1258  O O   . PRO A 1 174 ? -2.413  -18.096 -39.079  1.00 25.53  ? 167  PRO A O   1 
ATOM   1259  C CB  . PRO A 1 174 ? -0.203  -17.591 -37.067  1.00 21.30  ? 167  PRO A CB  1 
ATOM   1260  C CG  . PRO A 1 174 ? 0.307   -16.701 -35.961  1.00 21.70  ? 167  PRO A CG  1 
ATOM   1261  C CD  . PRO A 1 174 ? -0.389  -15.366 -36.113  1.00 22.35  ? 167  PRO A CD  1 
ATOM   1262  N N   . ARG A 1 175 ? -3.241  -16.523 -37.726  1.00 26.58  ? 168  ARG A N   1 
ATOM   1263  C CA  . ARG A 1 175 ? -4.682  -16.804 -37.970  1.00 27.10  ? 168  ARG A CA  1 
ATOM   1264  C C   . ARG A 1 175 ? -5.242  -15.819 -39.009  1.00 25.56  ? 168  ARG A C   1 
ATOM   1265  O O   . ARG A 1 175 ? -6.429  -15.899 -39.280  1.00 28.37  ? 168  ARG A O   1 
ATOM   1266  C CB  . ARG A 1 175 ? -5.434  -16.804 -36.634  1.00 26.56  ? 168  ARG A CB  1 
ATOM   1267  C CG  . ARG A 1 175 ? -4.983  -17.942 -35.728  1.00 27.60  ? 168  ARG A CG  1 
ATOM   1268  C CD  . ARG A 1 175 ? -5.500  -17.829 -34.315  1.00 30.40  ? 168  ARG A CD  1 
ATOM   1269  N NE  . ARG A 1 175 ? -5.315  -19.075 -33.586  1.00 30.89  ? 168  ARG A NE  1 
ATOM   1270  C CZ  . ARG A 1 175 ? -4.178  -19.449 -33.006  1.00 35.52  ? 168  ARG A CZ  1 
ATOM   1271  N NH1 . ARG A 1 175 ? -3.106  -18.667 -33.050  1.00 36.62  ? 168  ARG A NH1 1 
ATOM   1272  N NH2 . ARG A 1 175 ? -4.116  -20.605 -32.363  1.00 36.89  ? 168  ARG A NH2 1 
ATOM   1273  N N   . GLY A 1 176 ? -4.414  -14.936 -39.572  1.00 23.53  ? 169  GLY A N   1 
ATOM   1274  C CA  . GLY A 1 176 ? -4.824  -14.010 -40.644  1.00 19.98  ? 169  GLY A CA  1 
ATOM   1275  C C   . GLY A 1 176 ? -5.640  -12.824 -40.156  1.00 17.49  ? 169  GLY A C   1 
ATOM   1276  O O   . GLY A 1 176 ? -6.304  -12.229 -40.978  1.00 17.09  ? 169  GLY A O   1 
ATOM   1277  N N   . LYS A 1 177 ? -5.540  -12.434 -38.886  1.00 17.22  ? 170  LYS A N   1 
ATOM   1278  C CA  . LYS A 1 177 ? -6.296  -11.276 -38.340  1.00 17.55  ? 170  LYS A CA  1 
ATOM   1279  C C   . LYS A 1 177 ? -5.340  -10.198 -37.840  1.00 16.68  ? 170  LYS A C   1 
ATOM   1280  O O   . LYS A 1 177 ? -4.362  -10.542 -37.116  1.00 15.99  ? 170  LYS A O   1 
ATOM   1281  C CB  . LYS A 1 177 ? -7.219  -11.733 -37.213  1.00 19.30  ? 170  LYS A CB  1 
ATOM   1282  C CG  . LYS A 1 177 ? -8.249  -12.779 -37.633  1.00 20.39  ? 170  LYS A CG  1 
ATOM   1283  C CD  . LYS A 1 177 ? -9.058  -13.295 -36.471  1.00 23.26  ? 170  LYS A CD  1 
ATOM   1284  C CE  . LYS A 1 177 ? -10.204 -14.162 -36.940  1.00 26.07  ? 170  LYS A CE  1 
ATOM   1285  N NZ  . LYS A 1 177 ? -11.030 -14.612 -35.801  1.00 30.28  ? 170  LYS A NZ  1 
ATOM   1286  N N   . PHE A 1 178 ? -5.613  -8.948  -38.222  1.00 16.41  ? 171  PHE A N   1 
ATOM   1287  C CA  . PHE A 1 178 ? -4.667  -7.819  -38.047  1.00 18.48  ? 171  PHE A CA  1 
ATOM   1288  C C   . PHE A 1 178 ? -5.366  -6.552  -37.555  1.00 18.28  ? 171  PHE A C   1 
ATOM   1289  O O   . PHE A 1 178 ? -4.653  -5.627  -37.096  1.00 21.27  ? 171  PHE A O   1 
ATOM   1290  C CB  . PHE A 1 178 ? -3.911  -7.539  -39.355  1.00 18.89  ? 171  PHE A CB  1 
ATOM   1291  C CG  . PHE A 1 178 ? -3.136  -8.719  -39.886  1.00 18.71  ? 171  PHE A CG  1 
ATOM   1292  C CD1 . PHE A 1 178 ? -1.817  -8.934  -39.503  1.00 19.46  ? 171  PHE A CD1 1 
ATOM   1293  C CD2 . PHE A 1 178 ? -3.740  -9.637  -40.731  1.00 18.05  ? 171  PHE A CD2 1 
ATOM   1294  C CE1 . PHE A 1 178 ? -1.115  -10.032 -39.978  1.00 19.80  ? 171  PHE A CE1 1 
ATOM   1295  C CE2 . PHE A 1 178 ? -3.042  -10.744 -41.183  1.00 19.00  ? 171  PHE A CE2 1 
ATOM   1296  C CZ  . PHE A 1 178 ? -1.724  -10.928 -40.833  1.00 19.72  ? 171  PHE A CZ  1 
ATOM   1297  N N   . THR A 1 179 ? -6.678  -6.464  -37.661  1.00 17.10  ? 172  THR A N   1 
ATOM   1298  C CA  . THR A 1 179 ? -7.420  -5.243  -37.266  1.00 18.10  ? 172  THR A CA  1 
ATOM   1299  C C   . THR A 1 179 ? -7.612  -5.232  -35.731  1.00 18.67  ? 172  THR A C   1 
ATOM   1300  O O   . THR A 1 179 ? -7.785  -6.313  -35.122  1.00 17.93  ? 172  THR A O   1 
ATOM   1301  C CB  . THR A 1 179 ? -8.703  -5.128  -38.098  1.00 18.33  ? 172  THR A CB  1 
ATOM   1302  O OG1 . THR A 1 179 ? -8.346  -4.957  -39.475  1.00 19.08  ? 172  THR A OG1 1 
ATOM   1303  C CG2 . THR A 1 179 ? -9.584  -3.975  -37.664  1.00 19.44  ? 172  THR A CG2 1 
ATOM   1304  N N   . PHE A 1 180 ? -7.548  -4.048  -35.122  1.00 18.47  ? 173  PHE A N   1 
ATOM   1305  C CA  . PHE A 1 180 ? -7.805  -3.822  -33.681  1.00 18.40  ? 173  PHE A CA  1 
ATOM   1306  C C   . PHE A 1 180 ? -8.914  -2.790  -33.544  1.00 17.97  ? 173  PHE A C   1 
ATOM   1307  O O   . PHE A 1 180 ? -8.896  -1.801  -34.284  1.00 17.41  ? 173  PHE A O   1 
ATOM   1308  C CB  . PHE A 1 180 ? -6.553  -3.306  -32.975  1.00 20.01  ? 173  PHE A CB  1 
ATOM   1309  C CG  . PHE A 1 180 ? -5.505  -4.363  -32.757  1.00 21.45  ? 173  PHE A CG  1 
ATOM   1310  C CD1 . PHE A 1 180 ? -4.679  -4.758  -33.789  1.00 22.52  ? 173  PHE A CD1 1 
ATOM   1311  C CD2 . PHE A 1 180 ? -5.391  -5.009  -31.538  1.00 23.53  ? 173  PHE A CD2 1 
ATOM   1312  C CE1 . PHE A 1 180 ? -3.733  -5.751  -33.590  1.00 24.04  ? 173  PHE A CE1 1 
ATOM   1313  C CE2 . PHE A 1 180 ? -4.436  -5.993  -31.343  1.00 25.01  ? 173  PHE A CE2 1 
ATOM   1314  C CZ  . PHE A 1 180 ? -3.608  -6.362  -32.368  1.00 23.83  ? 173  PHE A CZ  1 
ATOM   1315  N N   A ILE A 1 181 ? -9.837  -3.026  -32.610  0.53 17.39  ? 174  ILE A N   1 
ATOM   1316  N N   B ILE A 1 181 ? -9.839  -3.027  -32.611  0.47 17.43  ? 174  ILE A N   1 
ATOM   1317  C CA  A ILE A 1 181 ? -10.937 -2.086  -32.264  0.53 16.62  ? 174  ILE A CA  1 
ATOM   1318  C CA  B ILE A 1 181 ? -10.938 -2.087  -32.264  0.47 16.73  ? 174  ILE A CA  1 
ATOM   1319  C C   A ILE A 1 181 ? -10.671 -1.528  -30.863  0.53 16.30  ? 174  ILE A C   1 
ATOM   1320  C C   B ILE A 1 181 ? -10.671 -1.528  -30.864  0.47 16.37  ? 174  ILE A C   1 
ATOM   1321  O O   A ILE A 1 181 ? -10.449 -2.327  -29.927  0.53 15.05  ? 174  ILE A O   1 
ATOM   1322  O O   B ILE A 1 181 ? -10.448 -2.327  -29.928  0.47 15.23  ? 174  ILE A O   1 
ATOM   1323  C CB  A ILE A 1 181 ? -12.311 -2.780  -32.328  0.53 16.73  ? 174  ILE A CB  1 
ATOM   1324  C CB  B ILE A 1 181 ? -12.311 -2.781  -32.326  0.47 16.87  ? 174  ILE A CB  1 
ATOM   1325  C CG1 A ILE A 1 181 ? -12.537 -3.469  -33.679  0.53 16.77  ? 174  ILE A CG1 1 
ATOM   1326  C CG1 B ILE A 1 181 ? -12.573 -3.439  -33.685  0.47 16.97  ? 174  ILE A CG1 1 
ATOM   1327  C CG2 A ILE A 1 181 ? -13.423 -1.798  -31.973  0.53 16.37  ? 174  ILE A CG2 1 
ATOM   1328  C CG2 B ILE A 1 181 ? -13.419 -1.804  -31.942  0.47 16.52  ? 174  ILE A CG2 1 
ATOM   1329  C CD1 A ILE A 1 181 ? -12.317 -2.587  -34.881  0.53 16.47  ? 174  ILE A CD1 1 
ATOM   1330  C CD1 B ILE A 1 181 ? -14.065 -3.562  -33.977  0.47 16.77  ? 174  ILE A CD1 1 
ATOM   1331  N N   . ALA A 1 182 ? -10.725 -0.203  -30.742  1.00 16.19  ? 175  ALA A N   1 
ATOM   1332  C CA  . ALA A 1 182 ? -10.709 0.529   -29.465  1.00 15.80  ? 175  ALA A CA  1 
ATOM   1333  C C   . ALA A 1 182 ? -11.963 1.389   -29.447  1.00 16.85  ? 175  ALA A C   1 
ATOM   1334  O O   . ALA A 1 182 ? -12.775 1.274   -30.392  1.00 15.52  ? 175  ALA A O   1 
ATOM   1335  C CB  . ALA A 1 182 ? -9.449  1.350   -29.345  1.00 16.57  ? 175  ALA A CB  1 
ATOM   1336  N N   . THR A 1 183 ? -12.144 2.184   -28.396  1.00 17.88  ? 176  THR A N   1 
ATOM   1337  C CA  . THR A 1 183 ? -13.342 3.023   -28.201  1.00 18.57  ? 176  THR A CA  1 
ATOM   1338  C C   . THR A 1 183 ? -12.906 4.484   -28.166  1.00 18.53  ? 176  THR A C   1 
ATOM   1339  O O   . THR A 1 183 ? -11.814 4.747   -27.724  1.00 17.93  ? 176  THR A O   1 
ATOM   1340  C CB  . THR A 1 183 ? -14.110 2.554   -26.961  1.00 20.37  ? 176  THR A CB  1 
ATOM   1341  O OG1 . THR A 1 183 ? -13.376 2.821   -25.766  1.00 18.08  ? 176  THR A OG1 1 
ATOM   1342  C CG2 . THR A 1 183 ? -14.427 1.074   -27.036  1.00 21.42  ? 176  THR A CG2 1 
ATOM   1343  N N   . SER A 1 184 ? -13.743 5.400   -28.639  1.00 20.20  ? 177  SER A N   1 
ATOM   1344  C CA  . SER A 1 184 ? -13.534 6.860   -28.490  1.00 20.71  ? 177  SER A CA  1 
ATOM   1345  C C   . SER A 1 184 ? -13.592 7.195   -26.998  1.00 20.92  ? 177  SER A C   1 
ATOM   1346  O O   . SER A 1 184 ? -14.279 6.465   -26.258  1.00 18.85  ? 177  SER A O   1 
ATOM   1347  C CB  . SER A 1 184 ? -14.534 7.660   -29.276  1.00 21.54  ? 177  SER A CB  1 
ATOM   1348  O OG  . SER A 1 184 ? -15.856 7.221   -29.007  1.00 21.18  ? 177  SER A OG  1 
ATOM   1349  N N   . GLY A 1 185 ? -12.865 8.243   -26.600  1.00 20.98  ? 178  GLY A N   1 
ATOM   1350  C CA  . GLY A 1 185 ? -12.619 8.620   -25.198  1.00 22.52  ? 178  GLY A CA  1 
ATOM   1351  C C   . GLY A 1 185 ? -11.571 7.728   -24.528  1.00 23.19  ? 178  GLY A C   1 
ATOM   1352  O O   . GLY A 1 185 ? -11.178 8.062   -23.404  1.00 23.02  ? 178  GLY A O   1 
ATOM   1353  N N   . ALA A 1 186 ? -11.133 6.637   -25.177  1.00 22.12  ? 179  ALA A N   1 
ATOM   1354  C CA  . ALA A 1 186 ? -10.245 5.608   -24.591  1.00 21.26  ? 179  ALA A CA  1 
ATOM   1355  C C   . ALA A 1 186 ? -8.825  6.175   -24.437  1.00 20.10  ? 179  ALA A C   1 
ATOM   1356  O O   . ALA A 1 186 ? -8.392  6.984   -25.264  1.00 19.78  ? 179  ALA A O   1 
ATOM   1357  C CB  . ALA A 1 186 ? -10.249 4.352   -25.420  1.00 22.25  ? 179  ALA A CB  1 
ATOM   1358  N N   . PHE A 1 187 ? -8.154  5.811   -23.348  1.00 18.33  ? 180  PHE A N   1 
ATOM   1359  C CA  . PHE A 1 187 ? -6.761  6.220   -23.067  1.00 17.99  ? 180  PHE A CA  1 
ATOM   1360  C C   . PHE A 1 187 ? -5.985  4.970   -22.688  1.00 17.47  ? 180  PHE A C   1 
ATOM   1361  O O   . PHE A 1 187 ? -6.352  4.374   -21.673  1.00 18.67  ? 180  PHE A O   1 
ATOM   1362  C CB  . PHE A 1 187 ? -6.681  7.292   -21.985  1.00 16.29  ? 180  PHE A CB  1 
ATOM   1363  C CG  . PHE A 1 187 ? -5.280  7.816   -21.865  1.00 15.46  ? 180  PHE A CG  1 
ATOM   1364  C CD1 . PHE A 1 187 ? -4.797  8.736   -22.773  1.00 16.09  ? 180  PHE A CD1 1 
ATOM   1365  C CD2 . PHE A 1 187 ? -4.397  7.281   -20.946  1.00 15.57  ? 180  PHE A CD2 1 
ATOM   1366  C CE1 . PHE A 1 187 ? -3.469  9.158   -22.710  1.00 17.35  ? 180  PHE A CE1 1 
ATOM   1367  C CE2 . PHE A 1 187 ? -3.077  7.717   -20.871  1.00 15.74  ? 180  PHE A CE2 1 
ATOM   1368  C CZ  . PHE A 1 187 ? -2.613  8.660   -21.751  1.00 15.95  ? 180  PHE A CZ  1 
ATOM   1369  N N   . HIS A 1 188 ? -5.009  4.580   -23.508  1.00 16.94  ? 181  HIS A N   1 
ATOM   1370  C CA  . HIS A 1 188 ? -4.235  3.324   -23.327  1.00 17.49  ? 181  HIS A CA  1 
ATOM   1371  C C   . HIS A 1 188 ? -2.729  3.614   -23.261  1.00 17.54  ? 181  HIS A C   1 
ATOM   1372  O O   . HIS A 1 188 ? -1.941  2.641   -23.260  1.00 17.41  ? 181  HIS A O   1 
ATOM   1373  C CB  . HIS A 1 188 ? -4.611  2.345   -24.448  1.00 18.36  ? 181  HIS A CB  1 
ATOM   1374  C CG  . HIS A 1 188 ? -6.063  2.035   -24.496  1.00 18.13  ? 181  HIS A CG  1 
ATOM   1375  N ND1 . HIS A 1 188 ? -6.702  1.351   -23.488  1.00 18.49  ? 181  HIS A ND1 1 
ATOM   1376  C CD2 . HIS A 1 188 ? -7.002  2.309   -25.417  1.00 18.39  ? 181  HIS A CD2 1 
ATOM   1377  C CE1 . HIS A 1 188 ? -7.988  1.219   -23.781  1.00 18.55  ? 181  HIS A CE1 1 
ATOM   1378  N NE2 . HIS A 1 188 ? -8.189  1.804   -24.963  1.00 18.92  ? 181  HIS A NE2 1 
ATOM   1379  N N   . GLY A 1 189 ? -2.344  4.892   -23.184  1.00 17.98  ? 182  GLY A N   1 
ATOM   1380  C CA  . GLY A 1 189 ? -0.933  5.314   -23.176  1.00 18.45  ? 182  GLY A CA  1 
ATOM   1381  C C   . GLY A 1 189 ? -0.511  6.084   -24.419  1.00 19.65  ? 182  GLY A C   1 
ATOM   1382  O O   . GLY A 1 189 ? -1.333  6.297   -25.325  1.00 19.50  ? 182  GLY A O   1 
ATOM   1383  N N   . LYS A 1 190 ? 0.767   6.452   -24.457  1.00 19.79  ? 183  LYS A N   1 
ATOM   1384  C CA  . LYS A 1 190 ? 1.327   7.476   -25.363  1.00 19.97  ? 183  LYS A CA  1 
ATOM   1385  C C   . LYS A 1 190 ? 2.550   6.944   -26.128  1.00 20.01  ? 183  LYS A C   1 
ATOM   1386  O O   . LYS A 1 190 ? 3.008   7.650   -27.054  1.00 18.45  ? 183  LYS A O   1 
ATOM   1387  C CB  . LYS A 1 190 ? 1.648   8.713   -24.521  1.00 20.81  ? 183  LYS A CB  1 
ATOM   1388  C CG  . LYS A 1 190 ? 0.432   9.388   -23.899  1.00 21.54  ? 183  LYS A CG  1 
ATOM   1389  C CD  . LYS A 1 190 ? 0.126   10.722  -24.554  1.00 21.96  ? 183  LYS A CD  1 
ATOM   1390  C CE  . LYS A 1 190 ? -0.876  11.532  -23.777  1.00 23.11  ? 183  LYS A CE  1 
ATOM   1391  N NZ  . LYS A 1 190 ? -0.276  12.674  -23.055  1.00 23.94  ? 183  LYS A NZ  1 
ATOM   1392  N N   . SER A 1 191 ? 3.048   5.745   -25.819  1.00 19.68  ? 184  SER A N   1 
ATOM   1393  C CA  . SER A 1 191 ? 3.986   5.034   -26.719  1.00 20.62  ? 184  SER A CA  1 
ATOM   1394  C C   . SER A 1 191 ? 3.226   4.734   -28.012  1.00 20.77  ? 184  SER A C   1 
ATOM   1395  O O   . SER A 1 191 ? 1.994   4.583   -27.945  1.00 18.48  ? 184  SER A O   1 
ATOM   1396  C CB  . SER A 1 191 ? 4.547   3.801   -26.087  1.00 21.05  ? 184  SER A CB  1 
ATOM   1397  O OG  . SER A 1 191 ? 3.515   2.899   -25.763  1.00 22.35  ? 184  SER A OG  1 
ATOM   1398  N N   . LEU A 1 192 ? 3.923   4.672   -29.145  1.00 20.57  ? 185  LEU A N   1 
ATOM   1399  C CA  . LEU A 1 192 ? 3.239   4.764   -30.461  1.00 23.07  ? 185  LEU A CA  1 
ATOM   1400  C C   . LEU A 1 192 ? 2.344   3.545   -30.725  1.00 23.55  ? 185  LEU A C   1 
ATOM   1401  O O   . LEU A 1 192 ? 1.365   3.720   -31.466  1.00 24.88  ? 185  LEU A O   1 
ATOM   1402  C CB  . LEU A 1 192 ? 4.274   4.996   -31.559  1.00 23.54  ? 185  LEU A CB  1 
ATOM   1403  C CG  . LEU A 1 192 ? 4.884   6.402   -31.517  1.00 24.10  ? 185  LEU A CG  1 
ATOM   1404  C CD1 . LEU A 1 192 ? 6.215   6.479   -32.241  1.00 23.66  ? 185  LEU A CD1 1 
ATOM   1405  C CD2 . LEU A 1 192 ? 3.913   7.438   -32.063  1.00 23.34  ? 185  LEU A CD2 1 
ATOM   1406  N N   . GLY A 1 193 ? 2.627   2.375   -30.145  1.00 23.32  ? 186  GLY A N   1 
ATOM   1407  C CA  . GLY A 1 193 ? 1.715   1.217   -30.246  1.00 20.63  ? 186  GLY A CA  1 
ATOM   1408  C C   . GLY A 1 193 ? 0.444   1.469   -29.462  1.00 20.15  ? 186  GLY A C   1 
ATOM   1409  O O   . GLY A 1 193 ? -0.693  1.312   -30.016  1.00 18.67  ? 186  GLY A O   1 
ATOM   1410  N N   . ALA A 1 194 ? 0.627   1.869   -28.207  1.00 19.01  ? 187  ALA A N   1 
ATOM   1411  C CA  . ALA A 1 194 ? -0.474  2.213   -27.282  1.00 18.15  ? 187  ALA A CA  1 
ATOM   1412  C C   . ALA A 1 194 ? -1.289  3.377   -27.858  1.00 17.10  ? 187  ALA A C   1 
ATOM   1413  O O   . ALA A 1 194 ? -2.504  3.316   -27.760  1.00 17.46  ? 187  ALA A O   1 
ATOM   1414  C CB  . ALA A 1 194 ? 0.090   2.541   -25.918  1.00 18.22  ? 187  ALA A CB  1 
ATOM   1415  N N   . LEU A 1 195 ? -0.642  4.397   -28.426  1.00 16.94  ? 188  LEU A N   1 
ATOM   1416  C CA  . LEU A 1 195 ? -1.315  5.655   -28.842  1.00 16.74  ? 188  LEU A CA  1 
ATOM   1417  C C   . LEU A 1 195 ? -2.207  5.372   -30.063  1.00 18.21  ? 188  LEU A C   1 
ATOM   1418  O O   . LEU A 1 195 ? -3.153  6.148   -30.301  1.00 17.52  ? 188  LEU A O   1 
ATOM   1419  C CB  . LEU A 1 195 ? -0.262  6.716   -29.149  1.00 16.67  ? 188  LEU A CB  1 
ATOM   1420  C CG  . LEU A 1 195 ? -0.829  8.051   -29.630  1.00 17.07  ? 188  LEU A CG  1 
ATOM   1421  C CD1 . LEU A 1 195 ? -1.614  8.728   -28.543  1.00 15.90  ? 188  LEU A CD1 1 
ATOM   1422  C CD2 . LEU A 1 195 ? 0.254   8.969   -30.165  1.00 18.27  ? 188  LEU A CD2 1 
ATOM   1423  N N   . SER A 1 196 ? -1.929  4.289   -30.802  1.00 17.90  ? 189  SER A N   1 
ATOM   1424  C CA  . SER A 1 196 ? -2.796  3.793   -31.902  1.00 17.60  ? 189  SER A CA  1 
ATOM   1425  C C   . SER A 1 196 ? -4.178  3.390   -31.370  1.00 17.21  ? 189  SER A C   1 
ATOM   1426  O O   . SER A 1 196 ? -5.143  3.476   -32.132  1.00 18.67  ? 189  SER A O   1 
ATOM   1427  C CB  . SER A 1 196 ? -2.134  2.656   -32.635  1.00 18.18  ? 189  SER A CB  1 
ATOM   1428  O OG  . SER A 1 196 ? -0.852  3.043   -33.112  1.00 18.57  ? 189  SER A OG  1 
ATOM   1429  N N   . ALA A 1 197 ? -4.266  2.960   -30.116  1.00 17.39  ? 190  ALA A N   1 
ATOM   1430  C CA  . ALA A 1 197 ? -5.530  2.597   -29.419  1.00 17.11  ? 190  ALA A CA  1 
ATOM   1431  C C   . ALA A 1 197 ? -6.100  3.820   -28.666  1.00 16.75  ? 190  ALA A C   1 
ATOM   1432  O O   . ALA A 1 197 ? -7.330  4.031   -28.709  1.00 17.35  ? 190  ALA A O   1 
ATOM   1433  C CB  . ALA A 1 197 ? -5.308  1.414   -28.498  1.00 16.50  ? 190  ALA A CB  1 
ATOM   1434  N N   . THR A 1 198 ? -5.258  4.629   -28.027  1.00 16.33  ? 191  THR A N   1 
ATOM   1435  C CA  . THR A 1 198 ? -5.670  5.922   -27.422  1.00 16.66  ? 191  THR A CA  1 
ATOM   1436  C C   . THR A 1 198 ? -6.506  6.676   -28.458  1.00 15.74  ? 191  THR A C   1 
ATOM   1437  O O   . THR A 1 198 ? -6.215  6.549   -29.637  1.00 16.40  ? 191  THR A O   1 
ATOM   1438  C CB  . THR A 1 198 ? -4.449  6.676   -26.878  1.00 17.65  ? 191  THR A CB  1 
ATOM   1439  O OG1 . THR A 1 198 ? -3.953  5.902   -25.781  1.00 18.26  ? 191  THR A OG1 1 
ATOM   1440  C CG2 . THR A 1 198 ? -4.768  8.084   -26.414  1.00 18.39  ? 191  THR A CG2 1 
ATOM   1441  N N   . ALA A 1 199 ? -7.544  7.387   -28.048  1.00 15.38  ? 192  ALA A N   1 
ATOM   1442  C CA  . ALA A 1 199 ? -8.587  7.862   -28.976  1.00 17.03  ? 192  ALA A CA  1 
ATOM   1443  C C   . ALA A 1 199 ? -8.623  9.377   -29.075  1.00 17.94  ? 192  ALA A C   1 
ATOM   1444  O O   . ALA A 1 199 ? -9.320  9.853   -29.942  1.00 18.55  ? 192  ALA A O   1 
ATOM   1445  C CB  . ALA A 1 199 ? -9.933  7.346   -28.556  1.00 17.01  ? 192  ALA A CB  1 
ATOM   1446  N N   . LYS A 1 200 ? -7.954  10.126  -28.217  1.00 20.42  ? 193  LYS A N   1 
ATOM   1447  C CA  . LYS A 1 200 ? -8.133  11.595  -28.269  1.00 22.96  ? 193  LYS A CA  1 
ATOM   1448  C C   . LYS A 1 200 ? -7.317  12.130  -29.452  1.00 24.29  ? 193  LYS A C   1 
ATOM   1449  O O   . LYS A 1 200 ? -6.111  11.772  -29.548  1.00 23.38  ? 193  LYS A O   1 
ATOM   1450  C CB  . LYS A 1 200 ? -7.738  12.259  -26.955  1.00 24.77  ? 193  LYS A CB  1 
ATOM   1451  C CG  . LYS A 1 200 ? -7.939  13.762  -26.990  1.00 27.22  ? 193  LYS A CG  1 
ATOM   1452  C CD  . LYS A 1 200 ? -6.886  14.510  -26.212  1.00 31.08  ? 193  LYS A CD  1 
ATOM   1453  C CE  . LYS A 1 200 ? -7.285  15.188  -24.926  1.00 32.94  ? 193  LYS A CE  1 
ATOM   1454  N NZ  . LYS A 1 200 ? -8.736  15.475  -24.877  1.00 38.55  ? 193  LYS A NZ  1 
ATOM   1455  N N   . SER A 1 201 ? -7.967  12.932  -30.312  1.00 23.21  ? 194  SER A N   1 
ATOM   1456  C CA  . SER A 1 201 ? -7.402  13.553  -31.530  1.00 23.15  ? 194  SER A CA  1 
ATOM   1457  C C   . SER A 1 201 ? -6.093  14.283  -31.229  1.00 23.21  ? 194  SER A C   1 
ATOM   1458  O O   . SER A 1 201 ? -5.098  14.000  -31.919  1.00 22.64  ? 194  SER A O   1 
ATOM   1459  C CB  . SER A 1 201 ? -8.363  14.527  -32.131  1.00 23.87  ? 194  SER A CB  1 
ATOM   1460  O OG  . SER A 1 201 ? -7.764  15.153  -33.271  1.00 27.77  ? 194  SER A OG  1 
ATOM   1461  N N   . THR A 1 202 ? -6.119  15.215  -30.271  1.00 23.65  ? 195  THR A N   1 
ATOM   1462  C CA  . THR A 1 202 ? -4.990  16.144  -29.991  1.00 26.43  ? 195  THR A CA  1 
ATOM   1463  C C   . THR A 1 202 ? -3.753  15.347  -29.546  1.00 24.46  ? 195  THR A C   1 
ATOM   1464  O O   . THR A 1 202 ? -2.659  15.866  -29.699  1.00 26.28  ? 195  THR A O   1 
ATOM   1465  C CB  . THR A 1 202 ? -5.345  17.221  -28.958  1.00 28.90  ? 195  THR A CB  1 
ATOM   1466  O OG1 . THR A 1 202 ? -5.336  16.638  -27.663  1.00 32.82  ? 195  THR A OG1 1 
ATOM   1467  C CG2 . THR A 1 202 ? -6.694  17.871  -29.167  1.00 29.38  ? 195  THR A CG2 1 
ATOM   1468  N N   . PHE A 1 203 ? -3.920  14.123  -29.057  1.00 22.91  ? 196  PHE A N   1 
ATOM   1469  C CA  . PHE A 1 203 ? -2.801  13.244  -28.638  1.00 23.20  ? 196  PHE A CA  1 
ATOM   1470  C C   . PHE A 1 203 ? -2.241  12.436  -29.817  1.00 22.97  ? 196  PHE A C   1 
ATOM   1471  O O   . PHE A 1 203 ? -1.107  11.944  -29.698  1.00 22.89  ? 196  PHE A O   1 
ATOM   1472  C CB  . PHE A 1 203 ? -3.253  12.320  -27.507  1.00 23.29  ? 196  PHE A CB  1 
ATOM   1473  C CG  . PHE A 1 203 ? -3.477  12.997  -26.178  1.00 22.72  ? 196  PHE A CG  1 
ATOM   1474  C CD1 . PHE A 1 203 ? -2.992  14.281  -25.928  1.00 23.78  ? 196  PHE A CD1 1 
ATOM   1475  C CD2 . PHE A 1 203 ? -4.141  12.338  -25.157  1.00 21.73  ? 196  PHE A CD2 1 
ATOM   1476  C CE1 . PHE A 1 203 ? -3.172  14.888  -24.690  1.00 22.31  ? 196  PHE A CE1 1 
ATOM   1477  C CE2 . PHE A 1 203 ? -4.288  12.941  -23.914  1.00 21.40  ? 196  PHE A CE2 1 
ATOM   1478  C CZ  . PHE A 1 203 ? -3.806  14.209  -23.683  1.00 20.94  ? 196  PHE A CZ  1 
ATOM   1479  N N   . ARG A 1 204 ? -2.987  12.317  -30.912  1.00 24.29  ? 197  ARG A N   1 
ATOM   1480  C CA  . ARG A 1 204 ? -2.669  11.367  -32.018  1.00 25.13  ? 197  ARG A CA  1 
ATOM   1481  C C   . ARG A 1 204 ? -2.209  12.090  -33.290  1.00 25.92  ? 197  ARG A C   1 
ATOM   1482  O O   . ARG A 1 204 ? -1.282  11.582  -33.938  1.00 22.94  ? 197  ARG A O   1 
ATOM   1483  C CB  . ARG A 1 204 ? -3.897  10.513  -32.348  1.00 23.31  ? 197  ARG A CB  1 
ATOM   1484  C CG  . ARG A 1 204 ? -4.288  9.535   -31.253  1.00 22.74  ? 197  ARG A CG  1 
ATOM   1485  C CD  . ARG A 1 204 ? -5.736  9.118   -31.393  1.00 21.75  ? 197  ARG A CD  1 
ATOM   1486  N NE  . ARG A 1 204 ? -6.050  8.634   -32.730  1.00 21.06  ? 197  ARG A NE  1 
ATOM   1487  C CZ  . ARG A 1 204 ? -5.842  7.405   -33.197  1.00 20.00  ? 197  ARG A CZ  1 
ATOM   1488  N NH1 . ARG A 1 204 ? -5.305  6.464   -32.439  1.00 20.30  ? 197  ARG A NH1 1 
ATOM   1489  N NH2 . ARG A 1 204 ? -6.219  7.116   -34.427  1.00 19.31  ? 197  ARG A NH2 1 
ATOM   1490  N N   . LYS A 1 205 ? -2.865  13.201  -33.645  1.00 29.77  ? 198  LYS A N   1 
ATOM   1491  C CA  . LYS A 1 205 ? -2.754  13.855  -34.976  1.00 31.23  ? 198  LYS A CA  1 
ATOM   1492  C C   . LYS A 1 205 ? -1.293  14.177  -35.280  1.00 30.40  ? 198  LYS A C   1 
ATOM   1493  O O   . LYS A 1 205 ? -0.828  13.846  -36.369  1.00 32.17  ? 198  LYS A O   1 
ATOM   1494  C CB  . LYS A 1 205 ? -3.648  15.097  -35.065  1.00 33.18  ? 198  LYS A CB  1 
ATOM   1495  C CG  . LYS A 1 205 ? -4.961  14.863  -35.799  1.00 36.99  ? 198  LYS A CG  1 
ATOM   1496  C CD  . LYS A 1 205 ? -5.924  16.053  -35.829  1.00 40.06  ? 198  LYS A CD  1 
ATOM   1497  C CE  . LYS A 1 205 ? -5.528  17.158  -36.787  1.00 38.19  ? 198  LYS A CE  1 
ATOM   1498  N NZ  . LYS A 1 205 ? -5.409  16.649  -38.171  1.00 40.99  ? 198  LYS A NZ  1 
ATOM   1499  N N   . PRO A 1 206 ? -0.519  14.812  -34.366  1.00 27.57  ? 199  PRO A N   1 
ATOM   1500  C CA  . PRO A 1 206 ? 0.871   15.162  -34.665  1.00 25.73  ? 199  PRO A CA  1 
ATOM   1501  C C   . PRO A 1 206 ? 1.745   13.962  -35.069  1.00 24.84  ? 199  PRO A C   1 
ATOM   1502  O O   . PRO A 1 206 ? 2.720   14.164  -35.794  1.00 26.28  ? 199  PRO A O   1 
ATOM   1503  C CB  . PRO A 1 206 ? 1.374   15.804  -33.359  1.00 25.26  ? 199  PRO A CB  1 
ATOM   1504  C CG  . PRO A 1 206 ? 0.123   16.304  -32.676  1.00 25.41  ? 199  PRO A CG  1 
ATOM   1505  C CD  . PRO A 1 206 ? -0.931  15.265  -33.030  1.00 27.69  ? 199  PRO A CD  1 
ATOM   1506  N N   . PHE A 1 207 ? 1.365   12.757  -34.626  1.00 22.95  ? 200  PHE A N   1 
ATOM   1507  C CA  . PHE A 1 207 ? 2.214   11.537  -34.631  1.00 22.72  ? 200  PHE A CA  1 
ATOM   1508  C C   . PHE A 1 207 ? 1.731   10.539  -35.688  1.00 22.28  ? 200  PHE A C   1 
ATOM   1509  O O   . PHE A 1 207 ? 2.344   9.483   -35.875  1.00 20.92  ? 200  PHE A O   1 
ATOM   1510  C CB  . PHE A 1 207 ? 2.256   10.984  -33.209  1.00 22.00  ? 200  PHE A CB  1 
ATOM   1511  C CG  . PHE A 1 207 ? 2.613   12.043  -32.197  1.00 22.56  ? 200  PHE A CG  1 
ATOM   1512  C CD1 . PHE A 1 207 ? 3.893   12.587  -32.158  1.00 23.11  ? 200  PHE A CD1 1 
ATOM   1513  C CD2 . PHE A 1 207 ? 1.660   12.529  -31.309  1.00 23.17  ? 200  PHE A CD2 1 
ATOM   1514  C CE1 . PHE A 1 207 ? 4.215   13.581  -31.244  1.00 22.81  ? 200  PHE A CE1 1 
ATOM   1515  C CE2 . PHE A 1 207 ? 1.981   13.529  -30.405  1.00 22.30  ? 200  PHE A CE2 1 
ATOM   1516  C CZ  . PHE A 1 207 ? 3.255   14.056  -30.378  1.00 22.61  ? 200  PHE A CZ  1 
ATOM   1517  N N   . MET A 1 208 ? 0.673   10.877  -36.406  1.00 22.72  ? 201  MET A N   1 
ATOM   1518  C CA  . MET A 1 208 ? 0.208   10.029  -37.521  1.00 24.57  ? 201  MET A CA  1 
ATOM   1519  C C   . MET A 1 208 ? 1.223   10.136  -38.659  1.00 24.28  ? 201  MET A C   1 
ATOM   1520  O O   . MET A 1 208 ? 1.898   11.160  -38.809  1.00 22.55  ? 201  MET A O   1 
ATOM   1521  C CB  . MET A 1 208 ? -1.174  10.459  -38.004  1.00 26.57  ? 201  MET A CB  1 
ATOM   1522  C CG  . MET A 1 208 ? -2.241  10.259  -36.958  1.00 27.79  ? 201  MET A CG  1 
ATOM   1523  S SD  . MET A 1 208 ? -3.819  10.964  -37.505  1.00 28.83  ? 201  MET A SD  1 
ATOM   1524  C CE  . MET A 1 208 ? -4.760  10.616  -36.026  1.00 29.38  ? 201  MET A CE  1 
ATOM   1525  N N   . PRO A 1 209 ? 1.375   9.080   -39.488  1.00 23.09  ? 202  PRO A N   1 
ATOM   1526  C CA  . PRO A 1 209 ? 0.598   7.844   -39.353  1.00 22.63  ? 202  PRO A CA  1 
ATOM   1527  C C   . PRO A 1 209 ? 1.014   6.913   -38.212  1.00 21.60  ? 202  PRO A C   1 
ATOM   1528  O O   . PRO A 1 209 ? 2.197   6.652   -38.044  1.00 19.81  ? 202  PRO A O   1 
ATOM   1529  C CB  . PRO A 1 209 ? 0.896   7.092   -40.654  1.00 22.75  ? 202  PRO A CB  1 
ATOM   1530  C CG  . PRO A 1 209 ? 2.265   7.584   -41.045  1.00 22.04  ? 202  PRO A CG  1 
ATOM   1531  C CD  . PRO A 1 209 ? 2.292   9.040   -40.629  1.00 22.09  ? 202  PRO A CD  1 
ATOM   1532  N N   . LEU A 1 210 ? 0.016   6.420   -37.483  1.00 20.59  ? 203  LEU A N   1 
ATOM   1533  C CA  . LEU A 1 210 ? 0.188   5.470   -36.354  1.00 20.35  ? 203  LEU A CA  1 
ATOM   1534  C C   . LEU A 1 210 ? 0.080   4.049   -36.904  1.00 19.93  ? 203  LEU A C   1 
ATOM   1535  O O   . LEU A 1 210 ? 0.112   3.905   -38.142  1.00 19.79  ? 203  LEU A O   1 
ATOM   1536  C CB  . LEU A 1 210 ? -0.875  5.779   -35.303  1.00 20.48  ? 203  LEU A CB  1 
ATOM   1537  C CG  . LEU A 1 210 ? -0.766  7.174   -34.690  1.00 20.80  ? 203  LEU A CG  1 
ATOM   1538  C CD1 . LEU A 1 210 ? -1.914  7.428   -33.740  1.00 21.46  ? 203  LEU A CD1 1 
ATOM   1539  C CD2 . LEU A 1 210 ? 0.546   7.343   -33.956  1.00 20.54  ? 203  LEU A CD2 1 
ATOM   1540  N N   . LEU A 1 211 ? 0.012   3.038   -36.041  1.00 19.60  ? 204  LEU A N   1 
ATOM   1541  C CA  . LEU A 1 211 ? -0.097  1.641   -36.512  1.00 21.36  ? 204  LEU A CA  1 
ATOM   1542  C C   . LEU A 1 211 ? -1.315  1.561   -37.408  1.00 22.73  ? 204  LEU A C   1 
ATOM   1543  O O   . LEU A 1 211 ? -2.377  2.101   -37.071  1.00 23.78  ? 204  LEU A O   1 
ATOM   1544  C CB  . LEU A 1 211 ? -0.275  0.672   -35.349  1.00 23.10  ? 204  LEU A CB  1 
ATOM   1545  C CG  . LEU A 1 211 ? 0.961   0.414   -34.498  1.00 25.66  ? 204  LEU A CG  1 
ATOM   1546  C CD1 . LEU A 1 211 ? 0.620   -0.574  -33.394  1.00 26.38  ? 204  LEU A CD1 1 
ATOM   1547  C CD2 . LEU A 1 211 ? 2.137   -0.092  -35.335  1.00 26.23  ? 204  LEU A CD2 1 
ATOM   1548  N N   . PRO A 1 212 ? -1.205  0.881   -38.565  1.00 23.73  ? 205  PRO A N   1 
ATOM   1549  C CA  . PRO A 1 212 ? -2.374  0.677   -39.412  1.00 24.92  ? 205  PRO A CA  1 
ATOM   1550  C C   . PRO A 1 212 ? -3.340  -0.337  -38.769  1.00 25.39  ? 205  PRO A C   1 
ATOM   1551  O O   . PRO A 1 212 ? -2.922  -1.118  -37.904  1.00 26.35  ? 205  PRO A O   1 
ATOM   1552  C CB  . PRO A 1 212 ? -1.756  0.232   -40.756  1.00 25.02  ? 205  PRO A CB  1 
ATOM   1553  C CG  . PRO A 1 212 ? -0.388  -0.318  -40.436  1.00 23.78  ? 205  PRO A CG  1 
ATOM   1554  C CD  . PRO A 1 212 ? 0.024   0.296   -39.114  1.00 24.32  ? 205  PRO A CD  1 
ATOM   1555  N N   . GLY A 1 213 ? -4.619  -0.263  -39.155  1.00 26.82  ? 206  GLY A N   1 
ATOM   1556  C CA  . GLY A 1 213 ? -5.642  -1.283  -38.850  1.00 24.78  ? 206  GLY A CA  1 
ATOM   1557  C C   . GLY A 1 213 ? -6.258  -1.102  -37.473  1.00 24.56  ? 206  GLY A C   1 
ATOM   1558  O O   . GLY A 1 213 ? -6.786  -2.091  -36.919  1.00 23.48  ? 206  GLY A O   1 
ATOM   1559  N N   . PHE A 1 214 ? -6.203  0.126   -36.946  1.00 25.14  ? 207  PHE A N   1 
ATOM   1560  C CA  . PHE A 1 214 ? -6.819  0.534   -35.656  1.00 24.87  ? 207  PHE A CA  1 
ATOM   1561  C C   . PHE A 1 214 ? -8.058  1.377   -35.957  1.00 26.56  ? 207  PHE A C   1 
ATOM   1562  O O   . PHE A 1 214 ? -7.951  2.413   -36.653  1.00 27.30  ? 207  PHE A O   1 
ATOM   1563  C CB  . PHE A 1 214 ? -5.810  1.257   -34.758  1.00 25.17  ? 207  PHE A CB  1 
ATOM   1564  C CG  . PHE A 1 214 ? -4.906  0.328   -33.977  1.00 24.17  ? 207  PHE A CG  1 
ATOM   1565  C CD1 . PHE A 1 214 ? -3.898  -0.386  -34.617  1.00 22.71  ? 207  PHE A CD1 1 
ATOM   1566  C CD2 . PHE A 1 214 ? -5.084  0.137   -32.611  1.00 22.20  ? 207  PHE A CD2 1 
ATOM   1567  C CE1 . PHE A 1 214 ? -3.083  -1.254  -33.906  1.00 22.00  ? 207  PHE A CE1 1 
ATOM   1568  C CE2 . PHE A 1 214 ? -4.267  -0.729  -31.908  1.00 21.43  ? 207  PHE A CE2 1 
ATOM   1569  C CZ  . PHE A 1 214 ? -3.273  -1.424  -32.551  1.00 21.00  ? 207  PHE A CZ  1 
ATOM   1570  N N   A ARG A 1 215 ? -9.207  0.931   -35.440  0.57 26.64  ? 208  ARG A N   1 
ATOM   1571  N N   B ARG A 1 215 ? -9.209  0.926   -35.444  0.43 27.22  ? 208  ARG A N   1 
ATOM   1572  C CA  A ARG A 1 215 ? -10.548 1.517   -35.682  0.57 25.48  ? 208  ARG A CA  1 
ATOM   1573  C CA  B ARG A 1 215 ? -10.545 1.532   -35.676  0.43 26.71  ? 208  ARG A CA  1 
ATOM   1574  C C   A ARG A 1 215 ? -11.240 1.718   -34.332  0.57 25.89  ? 208  ARG A C   1 
ATOM   1575  C C   B ARG A 1 215 ? -11.243 1.715   -34.330  0.43 26.56  ? 208  ARG A C   1 
ATOM   1576  O O   A ARG A 1 215 ? -11.038 0.892   -33.420  0.57 25.54  ? 208  ARG A O   1 
ATOM   1577  O O   B ARG A 1 215 ? -11.043 0.881   -33.421  0.43 26.36  ? 208  ARG A O   1 
ATOM   1578  C CB  A ARG A 1 215 ? -11.376 0.589   -36.574  0.57 25.43  ? 208  ARG A CB  1 
ATOM   1579  C CB  B ARG A 1 215 ? -11.377 0.692   -36.648  0.43 27.58  ? 208  ARG A CB  1 
ATOM   1580  C CG  A ARG A 1 215 ? -10.847 0.393   -37.995  0.57 26.05  ? 208  ARG A CG  1 
ATOM   1581  C CG  B ARG A 1 215 ? -11.208 1.151   -38.091  0.43 28.73  ? 208  ARG A CG  1 
ATOM   1582  C CD  A ARG A 1 215 ? -11.487 -0.852  -38.608  0.57 25.96  ? 208  ARG A CD  1 
ATOM   1583  C CD  B ARG A 1 215 ? -10.029 0.547   -38.829  0.43 29.15  ? 208  ARG A CD  1 
ATOM   1584  N NE  A ARG A 1 215 ? -11.626 -0.924  -40.061  0.57 23.85  ? 208  ARG A NE  1 
ATOM   1585  N NE  B ARG A 1 215 ? -9.824  1.277   -40.067  0.43 30.66  ? 208  ARG A NE  1 
ATOM   1586  C CZ  A ARG A 1 215 ? -10.720 -1.438  -40.872  0.57 24.90  ? 208  ARG A CZ  1 
ATOM   1587  C CZ  B ARG A 1 215 ? -8.663  1.772   -40.479  0.43 30.90  ? 208  ARG A CZ  1 
ATOM   1588  N NH1 A ARG A 1 215 ? -9.556  -1.854  -40.402  0.57 27.25  ? 208  ARG A NH1 1 
ATOM   1589  N NH1 B ARG A 1 215 ? -7.568  1.590   -39.763  0.43 31.40  ? 208  ARG A NH1 1 
ATOM   1590  N NH2 A ARG A 1 215 ? -10.932 -1.466  -42.171  0.57 24.09  ? 208  ARG A NH2 1 
ATOM   1591  N NH2 B ARG A 1 215 ? -8.597  2.425   -41.626  0.43 31.30  ? 208  ARG A NH2 1 
ATOM   1592  N N   . HIS A 1 216 ? -12.020 2.792   -34.220  1.00 25.94  ? 209  HIS A N   1 
ATOM   1593  C CA  . HIS A 1 216 ? -12.664 3.222   -32.959  1.00 24.98  ? 209  HIS A CA  1 
ATOM   1594  C C   . HIS A 1 216 ? -14.189 3.199   -33.112  1.00 22.90  ? 209  HIS A C   1 
ATOM   1595  O O   . HIS A 1 216 ? -14.720 3.703   -34.113  1.00 23.21  ? 209  HIS A O   1 
ATOM   1596  C CB  . HIS A 1 216 ? -12.074 4.576   -32.557  1.00 25.57  ? 209  HIS A CB  1 
ATOM   1597  C CG  . HIS A 1 216 ? -10.662 4.491   -32.071  1.00 24.95  ? 209  HIS A CG  1 
ATOM   1598  N ND1 . HIS A 1 216 ? -9.575  4.524   -32.924  1.00 23.31  ? 209  HIS A ND1 1 
ATOM   1599  C CD2 . HIS A 1 216 ? -10.152 4.377   -30.819  1.00 25.74  ? 209  HIS A CD2 1 
ATOM   1600  C CE1 . HIS A 1 216 ? -8.471  4.438   -32.224  1.00 21.28  ? 209  HIS A CE1 1 
ATOM   1601  N NE2 . HIS A 1 216 ? -8.786  4.359   -30.942  1.00 22.83  ? 209  HIS A NE2 1 
ATOM   1602  N N   . VAL A 1 217 ? -14.853 2.621   -32.121  1.00 23.33  ? 210  VAL A N   1 
ATOM   1603  C CA  . VAL A 1 217 ? -16.333 2.611   -31.968  1.00 21.41  ? 210  VAL A CA  1 
ATOM   1604  C C   . VAL A 1 217 ? -16.660 3.400   -30.699  1.00 20.54  ? 210  VAL A C   1 
ATOM   1605  O O   . VAL A 1 217 ? -15.772 3.669   -29.897  1.00 18.56  ? 210  VAL A O   1 
ATOM   1606  C CB  . VAL A 1 217 ? -16.862 1.162   -31.954  1.00 21.54  ? 210  VAL A CB  1 
ATOM   1607  C CG1 . VAL A 1 217 ? -16.541 0.455   -33.263  1.00 20.75  ? 210  VAL A CG1 1 
ATOM   1608  C CG2 . VAL A 1 217 ? -16.329 0.341   -30.784  1.00 20.77  ? 210  VAL A CG2 1 
ATOM   1609  N N   . PRO A 1 218 ? -17.917 3.880   -30.522  1.00 21.21  ? 211  PRO A N   1 
ATOM   1610  C CA  . PRO A 1 218 ? -18.349 4.494   -29.270  1.00 21.80  ? 211  PRO A CA  1 
ATOM   1611  C C   . PRO A 1 218 ? -18.274 3.496   -28.108  1.00 22.15  ? 211  PRO A C   1 
ATOM   1612  O O   . PRO A 1 218 ? -18.573 2.324   -28.311  1.00 21.83  ? 211  PRO A O   1 
ATOM   1613  C CB  . PRO A 1 218 ? -19.809 4.902   -29.513  1.00 23.55  ? 211  PRO A CB  1 
ATOM   1614  C CG  . PRO A 1 218 ? -19.919 4.986   -31.013  1.00 22.93  ? 211  PRO A CG  1 
ATOM   1615  C CD  . PRO A 1 218 ? -18.979 3.920   -31.540  1.00 21.84  ? 211  PRO A CD  1 
ATOM   1616  N N   . PHE A 1 219 ? -17.840 3.985   -26.941  1.00 21.86  ? 212  PHE A N   1 
ATOM   1617  C CA  . PHE A 1 219 ? -17.769 3.217   -25.680  1.00 21.14  ? 212  PHE A CA  1 
ATOM   1618  C C   . PHE A 1 219 ? -19.195 2.982   -25.177  1.00 22.71  ? 212  PHE A C   1 
ATOM   1619  O O   . PHE A 1 219 ? -19.992 3.945   -25.188  1.00 21.79  ? 212  PHE A O   1 
ATOM   1620  C CB  . PHE A 1 219 ? -16.954 3.977   -24.641  1.00 20.51  ? 212  PHE A CB  1 
ATOM   1621  C CG  . PHE A 1 219 ? -16.722 3.198   -23.371  1.00 20.38  ? 212  PHE A CG  1 
ATOM   1622  C CD1 . PHE A 1 219 ? -15.940 2.051   -23.353  1.00 19.68  ? 212  PHE A CD1 1 
ATOM   1623  C CD2 . PHE A 1 219 ? -17.317 3.600   -22.190  1.00 21.66  ? 212  PHE A CD2 1 
ATOM   1624  C CE1 . PHE A 1 219 ? -15.759 1.333   -22.183  1.00 19.89  ? 212  PHE A CE1 1 
ATOM   1625  C CE2 . PHE A 1 219 ? -17.131 2.883   -21.011  1.00 21.35  ? 212  PHE A CE2 1 
ATOM   1626  C CZ  . PHE A 1 219 ? -16.352 1.749   -21.009  1.00 20.08  ? 212  PHE A CZ  1 
ATOM   1627  N N   . GLY A 1 220 ? -19.496 1.748   -24.758  1.00 24.00  ? 213  GLY A N   1 
ATOM   1628  C CA  . GLY A 1 220 ? -20.761 1.386   -24.083  1.00 24.51  ? 213  GLY A CA  1 
ATOM   1629  C C   . GLY A 1 220 ? -21.882 1.153   -25.084  1.00 25.37  ? 213  GLY A C   1 
ATOM   1630  O O   . GLY A 1 220 ? -23.053 1.141   -24.656  1.00 28.34  ? 213  GLY A O   1 
ATOM   1631  N N   . ASN A 1 221 ? -21.533 0.953   -26.366  1.00 24.85  ? 214  ASN A N   1 
ATOM   1632  C CA  . ASN A 1 221 ? -22.460 0.763   -27.514  1.00 21.56  ? 214  ASN A CA  1 
ATOM   1633  C C   . ASN A 1 221 ? -22.136 -0.569  -28.180  1.00 21.47  ? 214  ASN A C   1 
ATOM   1634  O O   . ASN A 1 221 ? -21.363 -0.554  -29.140  1.00 22.98  ? 214  ASN A O   1 
ATOM   1635  C CB  . ASN A 1 221 ? -22.329 1.919   -28.505  1.00 20.72  ? 214  ASN A CB  1 
ATOM   1636  C CG  . ASN A 1 221 ? -23.304 1.853   -29.659  1.00 19.20  ? 214  ASN A CG  1 
ATOM   1637  O OD1 . ASN A 1 221 ? -23.852 0.785   -29.994  1.00 17.57  ? 214  ASN A OD1 1 
ATOM   1638  N ND2 . ASN A 1 221 ? -23.506 3.010   -30.269  1.00 17.99  ? 214  ASN A ND2 1 
ATOM   1639  N N   . ILE A 1 222 ? -22.718 -1.664  -27.695  1.00 21.15  ? 215  ILE A N   1 
ATOM   1640  C CA  . ILE A 1 222 ? -22.418 -3.045  -28.166  1.00 23.17  ? 215  ILE A CA  1 
ATOM   1641  C C   . ILE A 1 222 ? -22.810 -3.168  -29.639  1.00 24.25  ? 215  ILE A C   1 
ATOM   1642  O O   . ILE A 1 222 ? -22.141 -3.935  -30.368  1.00 24.91  ? 215  ILE A O   1 
ATOM   1643  C CB  . ILE A 1 222 ? -23.113 -4.116  -27.302  1.00 24.86  ? 215  ILE A CB  1 
ATOM   1644  C CG1 . ILE A 1 222 ? -22.556 -5.515  -27.596  1.00 26.10  ? 215  ILE A CG1 1 
ATOM   1645  C CG2 . ILE A 1 222 ? -24.631 -4.069  -27.459  1.00 24.29  ? 215  ILE A CG2 1 
ATOM   1646  C CD1 . ILE A 1 222 ? -21.115 -5.712  -27.171  1.00 25.86  ? 215  ILE A CD1 1 
ATOM   1647  N N   . GLU A 1 223 ? -23.846 -2.458  -30.079  1.00 25.39  ? 216  GLU A N   1 
ATOM   1648  C CA  . GLU A 1 223 ? -24.330 -2.637  -31.463  1.00 28.45  ? 216  GLU A CA  1 
ATOM   1649  C C   . GLU A 1 223 ? -23.310 -2.032  -32.443  1.00 24.96  ? 216  GLU A C   1 
ATOM   1650  O O   . GLU A 1 223 ? -23.020 -2.694  -33.465  1.00 23.09  ? 216  GLU A O   1 
ATOM   1651  C CB  . GLU A 1 223 ? -25.766 -2.129  -31.578  1.00 33.18  ? 216  GLU A CB  1 
ATOM   1652  C CG  . GLU A 1 223 ? -26.771 -3.121  -31.000  1.00 38.40  ? 216  GLU A CG  1 
ATOM   1653  C CD  . GLU A 1 223 ? -26.598 -4.572  -31.449  1.00 41.49  ? 216  GLU A CD  1 
ATOM   1654  O OE1 . GLU A 1 223 ? -26.259 -4.798  -32.626  1.00 41.78  ? 216  GLU A OE1 1 
ATOM   1655  O OE2 . GLU A 1 223 ? -26.806 -5.477  -30.622  1.00 44.85  ? 216  GLU A OE2 1 
ATOM   1656  N N   . ALA A 1 224 ? -22.758 -0.855  -32.131  1.00 22.71  ? 217  ALA A N   1 
ATOM   1657  C CA  . ALA A 1 224 ? -21.715 -0.161  -32.930  1.00 21.46  ? 217  ALA A CA  1 
ATOM   1658  C C   . ALA A 1 224 ? -20.493 -1.067  -33.084  1.00 20.18  ? 217  ALA A C   1 
ATOM   1659  O O   . ALA A 1 224 ? -19.914 -1.139  -34.178  1.00 17.99  ? 217  ALA A O   1 
ATOM   1660  C CB  . ALA A 1 224 ? -21.323 1.131   -32.270  1.00 21.14  ? 217  ALA A CB  1 
ATOM   1661  N N   . MET A 1 225 ? -20.152 -1.770  -32.017  1.00 20.63  ? 218  MET A N   1 
ATOM   1662  C CA  . MET A 1 225 ? -18.991 -2.681  -31.979  1.00 22.05  ? 218  MET A CA  1 
ATOM   1663  C C   . MET A 1 225 ? -19.302 -3.911  -32.838  1.00 21.16  ? 218  MET A C   1 
ATOM   1664  O O   . MET A 1 225 ? -18.414 -4.306  -33.596  1.00 23.55  ? 218  MET A O   1 
ATOM   1665  C CB  . MET A 1 225 ? -18.634 -3.097  -30.542  1.00 21.63  ? 218  MET A CB  1 
ATOM   1666  C CG  . MET A 1 225 ? -17.254 -3.748  -30.432  1.00 22.98  ? 218  MET A CG  1 
ATOM   1667  S SD  . MET A 1 225 ? -16.815 -4.325  -28.746  1.00 26.87  ? 218  MET A SD  1 
ATOM   1668  C CE  . MET A 1 225 ? -16.028 -2.823  -28.159  1.00 25.71  ? 218  MET A CE  1 
ATOM   1669  N N   . ARG A 1 226 ? -20.484 -4.506  -32.706  1.00 20.64  ? 219  ARG A N   1 
ATOM   1670  C CA  . ARG A 1 226 ? -20.911 -5.655  -33.548  1.00 20.81  ? 219  ARG A CA  1 
ATOM   1671  C C   . ARG A 1 226 ? -20.743 -5.283  -35.026  1.00 20.14  ? 219  ARG A C   1 
ATOM   1672  O O   . ARG A 1 226 ? -20.125 -6.062  -35.806  1.00 18.67  ? 219  ARG A O   1 
ATOM   1673  C CB  . ARG A 1 226 ? -22.372 -6.021  -33.276  1.00 21.43  ? 219  ARG A CB  1 
ATOM   1674  C CG  . ARG A 1 226 ? -22.924 -7.078  -34.224  1.00 22.68  ? 219  ARG A CG  1 
ATOM   1675  C CD  . ARG A 1 226 ? -24.197 -7.762  -33.750  1.00 23.07  ? 219  ARG A CD  1 
ATOM   1676  N NE  . ARG A 1 226 ? -23.941 -8.657  -32.630  1.00 23.74  ? 219  ARG A NE  1 
ATOM   1677  C CZ  . ARG A 1 226 ? -23.464 -9.897  -32.729  1.00 23.95  ? 219  ARG A CZ  1 
ATOM   1678  N NH1 . ARG A 1 226 ? -23.170 -10.420 -33.910  1.00 22.93  ? 219  ARG A NH1 1 
ATOM   1679  N NH2 . ARG A 1 226 ? -23.262 -10.600 -31.623  1.00 23.88  ? 219  ARG A NH2 1 
ATOM   1680  N N   . THR A 1 227 ? -21.289 -4.126  -35.389  1.00 20.31  ? 220  THR A N   1 
ATOM   1681  C CA  . THR A 1 227 ? -21.246 -3.575  -36.768  1.00 20.93  ? 220  THR A CA  1 
ATOM   1682  C C   . THR A 1 227 ? -19.790 -3.582  -37.245  1.00 20.80  ? 220  THR A C   1 
ATOM   1683  O O   . THR A 1 227 ? -19.521 -4.086  -38.360  1.00 22.72  ? 220  THR A O   1 
ATOM   1684  C CB  . THR A 1 227 ? -21.881 -2.176  -36.804  1.00 21.14  ? 220  THR A CB  1 
ATOM   1685  O OG1 . THR A 1 227 ? -23.292 -2.316  -36.582  1.00 21.68  ? 220  THR A OG1 1 
ATOM   1686  C CG2 . THR A 1 227 ? -21.601 -1.438  -38.095  1.00 20.26  ? 220  THR A CG2 1 
ATOM   1687  N N   . ALA A 1 228 ? -18.889 -3.026  -36.436  1.00 18.75  ? 221  ALA A N   1 
ATOM   1688  C CA  . ALA A 1 228 ? -17.482 -2.812  -36.824  1.00 18.61  ? 221  ALA A CA  1 
ATOM   1689  C C   . ALA A 1 228 ? -16.827 -4.172  -37.082  1.00 18.68  ? 221  ALA A C   1 
ATOM   1690  O O   . ALA A 1 228 ? -16.113 -4.299  -38.097  1.00 18.11  ? 221  ALA A O   1 
ATOM   1691  C CB  . ALA A 1 228 ? -16.762 -2.017  -35.775  1.00 17.95  ? 221  ALA A CB  1 
ATOM   1692  N N   . LEU A 1 229 ? -17.101 -5.158  -36.226  1.00 18.39  ? 222  LEU A N   1 
ATOM   1693  C CA  . LEU A 1 229 ? -16.512 -6.523  -36.331  1.00 19.33  ? 222  LEU A CA  1 
ATOM   1694  C C   . LEU A 1 229 ? -17.051 -7.200  -37.579  1.00 20.12  ? 222  LEU A C   1 
ATOM   1695  O O   . LEU A 1 229 ? -16.282 -7.875  -38.298  1.00 17.25  ? 222  LEU A O   1 
ATOM   1696  C CB  . LEU A 1 229 ? -16.853 -7.350  -35.092  1.00 20.48  ? 222  LEU A CB  1 
ATOM   1697  C CG  . LEU A 1 229 ? -15.861 -7.210  -33.936  1.00 21.22  ? 222  LEU A CG  1 
ATOM   1698  C CD1 . LEU A 1 229 ? -16.581 -7.154  -32.621  1.00 23.04  ? 222  LEU A CD1 1 
ATOM   1699  C CD2 . LEU A 1 229 ? -14.886 -8.351  -33.917  1.00 22.25  ? 222  LEU A CD2 1 
ATOM   1700  N N   . ASN A 1 230 ? -18.349 -7.020  -37.806  1.00 22.37  ? 223  ASN A N   1 
ATOM   1701  C CA  . ASN A 1 230 ? -19.061 -7.653  -38.939  1.00 23.60  ? 223  ASN A CA  1 
ATOM   1702  C C   . ASN A 1 230 ? -18.543 -7.081  -40.269  1.00 22.22  ? 223  ASN A C   1 
ATOM   1703  O O   . ASN A 1 230 ? -18.277 -7.885  -41.164  1.00 21.82  ? 223  ASN A O   1 
ATOM   1704  C CB  . ASN A 1 230 ? -20.575 -7.493  -38.795  1.00 23.92  ? 223  ASN A CB  1 
ATOM   1705  C CG  . ASN A 1 230 ? -21.280 -8.540  -39.616  1.00 25.67  ? 223  ASN A CG  1 
ATOM   1706  O OD1 . ASN A 1 230 ? -20.917 -9.713  -39.543  1.00 27.66  ? 223  ASN A OD1 1 
ATOM   1707  N ND2 . ASN A 1 230 ? -22.237 -8.125  -40.428  1.00 27.75  ? 223  ASN A ND2 1 
ATOM   1708  N N   . GLU A 1 231 ? -18.444 -5.749  -40.377  1.00 21.23  ? 224  GLU A N   1 
ATOM   1709  C CA  . GLU A 1 231 ? -17.993 -5.018  -41.590  1.00 20.58  ? 224  GLU A CA  1 
ATOM   1710  C C   . GLU A 1 231 ? -16.541 -5.393  -41.880  1.00 20.14  ? 224  GLU A C   1 
ATOM   1711  O O   . GLU A 1 231 ? -16.219 -5.614  -43.058  1.00 20.01  ? 224  GLU A O   1 
ATOM   1712  C CB  . GLU A 1 231 ? -18.144 -3.503  -41.423  1.00 21.93  ? 224  GLU A CB  1 
ATOM   1713  C CG  . GLU A 1 231 ? -19.590 -3.026  -41.301  1.00 24.96  ? 224  GLU A CG  1 
ATOM   1714  C CD  . GLU A 1 231 ? -20.490 -3.191  -42.532  1.00 26.83  ? 224  GLU A CD  1 
ATOM   1715  O OE1 . GLU A 1 231 ? -20.111 -2.694  -43.655  1.00 28.28  ? 224  GLU A OE1 1 
ATOM   1716  O OE2 . GLU A 1 231 ? -21.584 -3.834  -42.380  1.00 28.95  ? 224  GLU A OE2 1 
ATOM   1717  N N   . CYS A 1 232 ? -15.711 -5.504  -40.837  1.00 19.80  ? 225  CYS A N   1 
ATOM   1718  C CA  . CYS A 1 232 ? -14.295 -5.932  -40.956  1.00 20.45  ? 225  CYS A CA  1 
ATOM   1719  C C   . CYS A 1 232 ? -14.229 -7.361  -41.512  1.00 20.57  ? 225  CYS A C   1 
ATOM   1720  O O   . CYS A 1 232 ? -13.354 -7.624  -42.376  1.00 19.54  ? 225  CYS A O   1 
ATOM   1721  C CB  . CYS A 1 232 ? -13.564 -5.789  -39.626  1.00 19.86  ? 225  CYS A CB  1 
ATOM   1722  S SG  . CYS A 1 232 ? -13.138 -4.069  -39.250  1.00 20.61  ? 225  CYS A SG  1 
ATOM   1723  N N   . LYS A 1 233 ? -15.131 -8.238  -41.075  1.00 20.93  ? 226  LYS A N   1 
ATOM   1724  C CA  . LYS A 1 233 ? -15.210 -9.646  -41.545  1.00 22.82  ? 226  LYS A CA  1 
ATOM   1725  C C   . LYS A 1 233 ? -15.611 -9.676  -43.023  1.00 25.03  ? 226  LYS A C   1 
ATOM   1726  O O   . LYS A 1 233 ? -14.957 -10.427 -43.818  1.00 25.89  ? 226  LYS A O   1 
ATOM   1727  C CB  . LYS A 1 233 ? -16.235 -10.407 -40.709  1.00 25.82  ? 226  LYS A CB  1 
ATOM   1728  C CG  . LYS A 1 233 ? -16.501 -11.832 -41.140  1.00 27.72  ? 226  LYS A CG  1 
ATOM   1729  C CD  . LYS A 1 233 ? -17.432 -12.508 -40.150  1.00 31.50  ? 226  LYS A CD  1 
ATOM   1730  C CE  . LYS A 1 233 ? -18.018 -13.812 -40.643  1.00 34.62  ? 226  LYS A CE  1 
ATOM   1731  N NZ  . LYS A 1 233 ? -16.996 -14.873 -40.845  1.00 37.38  ? 226  LYS A NZ  1 
ATOM   1732  N N   . LYS A 1 234 ? -16.631 -8.891  -43.392  1.00 24.05  ? 227  LYS A N   1 
ATOM   1733  C CA  . LYS A 1 234 ? -17.132 -8.794  -44.789  1.00 24.35  ? 227  LYS A CA  1 
ATOM   1734  C C   . LYS A 1 234 ? -16.000 -8.396  -45.746  1.00 22.32  ? 227  LYS A C   1 
ATOM   1735  O O   . LYS A 1 234 ? -15.969 -8.969  -46.829  1.00 23.39  ? 227  LYS A O   1 
ATOM   1736  C CB  . LYS A 1 234 ? -18.285 -7.785  -44.894  1.00 25.87  ? 227  LYS A CB  1 
ATOM   1737  C CG  . LYS A 1 234 ? -19.553 -8.153  -44.141  1.00 27.84  ? 227  LYS A CG  1 
ATOM   1738  C CD  . LYS A 1 234 ? -20.751 -7.404  -44.668  1.00 31.36  ? 227  LYS A CD  1 
ATOM   1739  C CE  . LYS A 1 234 ? -21.710 -6.921  -43.605  1.00 34.07  ? 227  LYS A CE  1 
ATOM   1740  N NZ  . LYS A 1 234 ? -22.841 -6.171  -44.203  1.00 37.66  ? 227  LYS A NZ  1 
ATOM   1741  N N   . THR A 1 235 ? -15.131 -7.446  -45.372  1.00 19.53  ? 228  THR A N   1 
ATOM   1742  C CA  . THR A 1 235 ? -14.147 -6.801  -46.273  1.00 17.81  ? 228  THR A CA  1 
ATOM   1743  C C   . THR A 1 235 ? -12.812 -7.536  -46.205  1.00 17.32  ? 228  THR A C   1 
ATOM   1744  O O   . THR A 1 235 ? -11.870 -7.089  -46.892  1.00 17.38  ? 228  THR A O   1 
ATOM   1745  C CB  . THR A 1 235 ? -13.973 -5.316  -45.948  1.00 17.41  ? 228  THR A CB  1 
ATOM   1746  O OG1 . THR A 1 235 ? -13.523 -5.190  -44.603  1.00 19.57  ? 228  THR A OG1 1 
ATOM   1747  C CG2 . THR A 1 235 ? -15.248 -4.535  -46.138  1.00 17.95  ? 228  THR A CG2 1 
ATOM   1748  N N   . GLY A 1 236 ? -12.724 -8.609  -45.423  1.00 16.50  ? 229  GLY A N   1 
ATOM   1749  C CA  . GLY A 1 236 ? -11.480 -9.388  -45.259  1.00 16.60  ? 229  GLY A CA  1 
ATOM   1750  C C   . GLY A 1 236 ? -10.447 -8.730  -44.350  1.00 16.59  ? 229  GLY A C   1 
ATOM   1751  O O   . GLY A 1 236 ? -9.294  -9.178  -44.407  1.00 16.80  ? 229  GLY A O   1 
ATOM   1752  N N   . ASP A 1 237 ? -10.851 -7.758  -43.509  1.00 16.26  ? 230  ASP A N   1 
ATOM   1753  C CA  . ASP A 1 237 ? -9.990  -7.016  -42.541  1.00 15.28  ? 230  ASP A CA  1 
ATOM   1754  C C   . ASP A 1 237 ? -10.374 -7.446  -41.116  1.00 15.04  ? 230  ASP A C   1 
ATOM   1755  O O   . ASP A 1 237 ? -10.611 -6.568  -40.260  1.00 13.28  ? 230  ASP A O   1 
ATOM   1756  C CB  . ASP A 1 237 ? -10.132 -5.498  -42.686  1.00 15.40  ? 230  ASP A CB  1 
ATOM   1757  C CG  . ASP A 1 237 ? -9.932  -4.975  -44.101  1.00 17.54  ? 230  ASP A CG  1 
ATOM   1758  O OD1 . ASP A 1 237 ? -8.750  -4.902  -44.540  1.00 16.60  ? 230  ASP A OD1 1 
ATOM   1759  O OD2 . ASP A 1 237 ? -10.959 -4.617  -44.768  1.00 17.61  ? 230  ASP A OD2 1 
ATOM   1760  N N   . ASP A 1 238 ? -10.428 -8.756  -40.889  1.00 16.14  ? 231  ASP A N   1 
ATOM   1761  C CA  . ASP A 1 238 ? -10.967 -9.390  -39.653  1.00 18.13  ? 231  ASP A CA  1 
ATOM   1762  C C   . ASP A 1 238 ? -10.236 -8.868  -38.408  1.00 17.16  ? 231  ASP A C   1 
ATOM   1763  O O   . ASP A 1 238 ? -9.024  -8.599  -38.465  1.00 16.05  ? 231  ASP A O   1 
ATOM   1764  C CB  . ASP A 1 238 ? -10.862 -10.921 -39.701  1.00 20.02  ? 231  ASP A CB  1 
ATOM   1765  C CG  . ASP A 1 238 ? -11.531 -11.517 -40.919  1.00 22.24  ? 231  ASP A CG  1 
ATOM   1766  O OD1 . ASP A 1 238 ? -10.910 -11.430 -42.031  1.00 25.14  ? 231  ASP A OD1 1 
ATOM   1767  O OD2 . ASP A 1 238 ? -12.695 -12.004 -40.770  1.00 25.07  ? 231  ASP A OD2 1 
ATOM   1768  N N   . VAL A 1 239 ? -10.959 -8.778  -37.303  1.00 16.90  ? 232  VAL A N   1 
ATOM   1769  C CA  . VAL A 1 239 ? -10.489 -8.117  -36.054  1.00 16.72  ? 232  VAL A CA  1 
ATOM   1770  C C   . VAL A 1 239 ? -9.685  -9.126  -35.238  1.00 15.51  ? 232  VAL A C   1 
ATOM   1771  O O   . VAL A 1 239 ? -10.199 -10.219 -34.971  1.00 14.93  ? 232  VAL A O   1 
ATOM   1772  C CB  . VAL A 1 239 ? -11.690 -7.524  -35.292  1.00 18.16  ? 232  VAL A CB  1 
ATOM   1773  C CG1 . VAL A 1 239 ? -11.328 -7.023  -33.897  1.00 19.56  ? 232  VAL A CG1 1 
ATOM   1774  C CG2 . VAL A 1 239 ? -12.327 -6.401  -36.096  1.00 18.66  ? 232  VAL A CG2 1 
ATOM   1775  N N   . ALA A 1 240 ? -8.448  -8.770  -34.904  1.00 15.84  ? 233  ALA A N   1 
ATOM   1776  C CA  . ALA A 1 240 ? -7.538  -9.566  -34.052  1.00 16.53  ? 233  ALA A CA  1 
ATOM   1777  C C   . ALA A 1 240 ? -7.980  -9.420  -32.592  1.00 16.75  ? 233  ALA A C   1 
ATOM   1778  O O   . ALA A 1 240 ? -8.029  -10.453 -31.876  1.00 17.29  ? 233  ALA A O   1 
ATOM   1779  C CB  . ALA A 1 240 ? -6.115  -9.114  -34.223  1.00 17.59  ? 233  ALA A CB  1 
ATOM   1780  N N   . ALA A 1 241 ? -8.293  -8.198  -32.156  1.00 15.94  ? 234  ALA A N   1 
ATOM   1781  C CA  . ALA A 1 241 ? -8.587  -7.927  -30.733  1.00 16.86  ? 234  ALA A CA  1 
ATOM   1782  C C   . ALA A 1 241 ? -9.452  -6.683  -30.591  1.00 16.38  ? 234  ALA A C   1 
ATOM   1783  O O   . ALA A 1 241 ? -9.361  -5.762  -31.411  1.00 16.21  ? 234  ALA A O   1 
ATOM   1784  C CB  . ALA A 1 241 ? -7.306  -7.764  -29.949  1.00 17.59  ? 234  ALA A CB  1 
ATOM   1785  N N   . VAL A 1 242 ? -10.244 -6.692  -29.538  1.00 15.69  ? 235  VAL A N   1 
ATOM   1786  C CA  . VAL A 1 242 ? -10.884 -5.488  -28.970  1.00 16.05  ? 235  VAL A CA  1 
ATOM   1787  C C   . VAL A 1 242 ? -10.120 -5.132  -27.692  1.00 15.73  ? 235  VAL A C   1 
ATOM   1788  O O   . VAL A 1 242 ? -9.897  -6.028  -26.842  1.00 14.44  ? 235  VAL A O   1 
ATOM   1789  C CB  . VAL A 1 242 ? -12.370 -5.749  -28.674  1.00 16.23  ? 235  VAL A CB  1 
ATOM   1790  C CG1 . VAL A 1 242 ? -13.038 -4.512  -28.074  1.00 16.43  ? 235  VAL A CG1 1 
ATOM   1791  C CG2 . VAL A 1 242 ? -13.096 -6.264  -29.907  1.00 15.84  ? 235  VAL A CG2 1 
ATOM   1792  N N   . ILE A 1 243 ? -9.763  -3.860  -27.553  1.00 15.62  ? 236  ILE A N   1 
ATOM   1793  C CA  . ILE A 1 243 ? -9.150  -3.314  -26.315  1.00 15.63  ? 236  ILE A CA  1 
ATOM   1794  C C   . ILE A 1 243 ? -10.070 -2.219  -25.790  1.00 15.38  ? 236  ILE A C   1 
ATOM   1795  O O   . ILE A 1 243 ? -10.461 -1.366  -26.582  1.00 13.86  ? 236  ILE A O   1 
ATOM   1796  C CB  . ILE A 1 243 ? -7.720  -2.789  -26.572  1.00 15.29  ? 236  ILE A CB  1 
ATOM   1797  C CG1 . ILE A 1 243 ? -7.086  -2.277  -25.275  1.00 15.26  ? 236  ILE A CG1 1 
ATOM   1798  C CG2 . ILE A 1 243 ? -7.702  -1.719  -27.657  1.00 14.93  ? 236  ILE A CG2 1 
ATOM   1799  C CD1 . ILE A 1 243 ? -5.630  -1.894  -25.419  1.00 15.20  ? 236  ILE A CD1 1 
ATOM   1800  N N   . LEU A 1 244 ? -10.337 -2.225  -24.486  1.00 17.20  ? 237  LEU A N   1 
ATOM   1801  C CA  . LEU A 1 244 ? -11.156 -1.184  -23.810  1.00 18.63  ? 237  LEU A CA  1 
ATOM   1802  C C   . LEU A 1 244 ? -10.823 -1.139  -22.322  1.00 17.96  ? 237  LEU A C   1 
ATOM   1803  O O   . LEU A 1 244 ? -10.365 -2.156  -21.769  1.00 17.64  ? 237  LEU A O   1 
ATOM   1804  C CB  . LEU A 1 244 ? -12.653 -1.444  -24.056  1.00 20.64  ? 237  LEU A CB  1 
ATOM   1805  C CG  . LEU A 1 244 ? -13.279 -2.690  -23.417  1.00 21.56  ? 237  LEU A CG  1 
ATOM   1806  C CD1 . LEU A 1 244 ? -14.773 -2.715  -23.673  1.00 22.05  ? 237  LEU A CD1 1 
ATOM   1807  C CD2 . LEU A 1 244 ? -12.676 -3.982  -23.947  1.00 22.23  ? 237  LEU A CD2 1 
ATOM   1808  N N   . GLU A 1 245 ? -11.008 0.034   -21.729  1.00 18.03  ? 238  GLU A N   1 
ATOM   1809  C CA  . GLU A 1 245 ? -11.036 0.211   -20.261  1.00 18.84  ? 238  GLU A CA  1 
ATOM   1810  C C   . GLU A 1 245 ? -12.415 -0.216  -19.781  1.00 19.30  ? 238  GLU A C   1 
ATOM   1811  O O   . GLU A 1 245 ? -13.403 0.119   -20.430  1.00 19.98  ? 238  GLU A O   1 
ATOM   1812  C CB  . GLU A 1 245 ? -10.825 1.672   -19.867  1.00 19.46  ? 238  GLU A CB  1 
ATOM   1813  C CG  . GLU A 1 245 ? -9.556  2.305   -20.428  1.00 19.10  ? 238  GLU A CG  1 
ATOM   1814  C CD  . GLU A 1 245 ? -9.625  3.821   -20.483  1.00 19.39  ? 238  GLU A CD  1 
ATOM   1815  O OE1 . GLU A 1 245 ? -9.379  4.490   -19.439  1.00 19.16  ? 238  GLU A OE1 1 
ATOM   1816  O OE2 . GLU A 1 245 ? -9.976  4.329   -21.555  1.00 18.90  ? 238  GLU A OE2 1 
ATOM   1817  N N   . PRO A 1 246 ? -12.548 -0.952  -18.658  1.00 18.40  ? 239  PRO A N   1 
ATOM   1818  C CA  . PRO A 1 246 ? -13.871 -1.303  -18.133  1.00 17.85  ? 239  PRO A CA  1 
ATOM   1819  C C   . PRO A 1 246 ? -14.690 -0.056  -17.769  1.00 17.24  ? 239  PRO A C   1 
ATOM   1820  O O   . PRO A 1 246 ? -15.898 -0.103  -17.821  1.00 18.30  ? 239  PRO A O   1 
ATOM   1821  C CB  . PRO A 1 246 ? -13.597 -2.106  -16.866  1.00 18.38  ? 239  PRO A CB  1 
ATOM   1822  C CG  . PRO A 1 246 ? -12.135 -2.500  -16.963  1.00 18.87  ? 239  PRO A CG  1 
ATOM   1823  C CD  . PRO A 1 246 ? -11.457 -1.464  -17.834  1.00 18.78  ? 239  PRO A CD  1 
ATOM   1824  N N   . ILE A 1 247 ? -13.994 0.998   -17.363  1.00 17.97  ? 240  ILE A N   1 
ATOM   1825  C CA  . ILE A 1 247 ? -14.505 2.364   -17.063  1.00 20.32  ? 240  ILE A CA  1 
ATOM   1826  C C   . ILE A 1 247 ? -13.438 3.309   -17.580  1.00 21.68  ? 240  ILE A C   1 
ATOM   1827  O O   . ILE A 1 247 ? -12.252 3.085   -17.268  1.00 24.38  ? 240  ILE A O   1 
ATOM   1828  C CB  . ILE A 1 247 ? -14.758 2.569   -15.549  1.00 23.13  ? 240  ILE A CB  1 
ATOM   1829  C CG1 . ILE A 1 247 ? -15.819 1.588   -15.040  1.00 23.96  ? 240  ILE A CG1 1 
ATOM   1830  C CG2 . ILE A 1 247 ? -15.157 4.007   -15.239  1.00 23.54  ? 240  ILE A CG2 1 
ATOM   1831  C CD1 . ILE A 1 247 ? -15.812 1.369   -13.551  1.00 25.91  ? 240  ILE A CD1 1 
ATOM   1832  N N   . GLN A 1 248 ? -13.822 4.287   -18.382  1.00 22.12  ? 241  GLN A N   1 
ATOM   1833  C CA  . GLN A 1 248 ? -12.843 5.199   -19.001  1.00 23.40  ? 241  GLN A CA  1 
ATOM   1834  C C   . GLN A 1 248 ? -12.462 6.226   -17.948  1.00 26.04  ? 241  GLN A C   1 
ATOM   1835  O O   . GLN A 1 248 ? -13.371 6.876   -17.412  1.00 25.62  ? 241  GLN A O   1 
ATOM   1836  C CB  . GLN A 1 248 ? -13.405 5.798   -20.276  1.00 24.76  ? 241  GLN A CB  1 
ATOM   1837  C CG  . GLN A 1 248 ? -13.639 4.735   -21.342  1.00 25.81  ? 241  GLN A CG  1 
ATOM   1838  C CD  . GLN A 1 248 ? -14.012 5.355   -22.662  1.00 27.09  ? 241  GLN A CD  1 
ATOM   1839  O OE1 . GLN A 1 248 ? -14.643 6.415   -22.733  1.00 27.15  ? 241  GLN A OE1 1 
ATOM   1840  N NE2 . GLN A 1 248 ? -13.613 4.688   -23.728  1.00 29.64  ? 241  GLN A NE2 1 
ATOM   1841  N N   . GLY A 1 249 ? -11.176 6.264   -17.604  1.00 26.71  ? 242  GLY A N   1 
ATOM   1842  C CA  . GLY A 1 249 ? -10.617 7.236   -16.656  1.00 28.81  ? 242  GLY A CA  1 
ATOM   1843  C C   . GLY A 1 249 ? -10.471 8.585   -17.321  1.00 29.88  ? 242  GLY A C   1 
ATOM   1844  O O   . GLY A 1 249 ? -11.214 9.510   -16.969  1.00 29.00  ? 242  GLY A O   1 
ATOM   1845  N N   . GLU A 1 250 ? -9.549  8.699   -18.275  1.00 32.98  ? 243  GLU A N   1 
ATOM   1846  C CA  . GLU A 1 250 ? -9.188  10.005  -18.881  1.00 35.70  ? 243  GLU A CA  1 
ATOM   1847  C C   . GLU A 1 250 ? -10.403 10.527  -19.659  1.00 34.31  ? 243  GLU A C   1 
ATOM   1848  O O   . GLU A 1 250 ? -10.533 11.759  -19.804  1.00 31.76  ? 243  GLU A O   1 
ATOM   1849  C CB  . GLU A 1 250 ? -7.917  9.853   -19.718  1.00 39.88  ? 243  GLU A CB  1 
ATOM   1850  C CG  . GLU A 1 250 ? -6.711  9.311   -18.944  1.00 44.82  ? 243  GLU A CG  1 
ATOM   1851  C CD  . GLU A 1 250 ? -6.341  9.971   -17.615  1.00 51.37  ? 243  GLU A CD  1 
ATOM   1852  O OE1 . GLU A 1 250 ? -6.512  11.200  -17.491  1.00 57.25  ? 243  GLU A OE1 1 
ATOM   1853  O OE2 . GLU A 1 250 ? -5.873  9.256   -16.688  1.00 52.27  ? 243  GLU A OE2 1 
ATOM   1854  N N   . GLY A 1 251 ? -11.279 9.610   -20.089  1.00 34.84  ? 244  GLY A N   1 
ATOM   1855  C CA  . GLY A 1 251 ? -12.582 9.879   -20.731  1.00 32.33  ? 244  GLY A CA  1 
ATOM   1856  C C   . GLY A 1 251 ? -13.507 10.683  -19.840  1.00 33.92  ? 244  GLY A C   1 
ATOM   1857  O O   . GLY A 1 251 ? -14.459 11.255  -20.393  1.00 36.65  ? 244  GLY A O   1 
ATOM   1858  N N   . GLY A 1 252 ? -13.267 10.695  -18.515  1.00 33.66  ? 245  GLY A N   1 
ATOM   1859  C CA  . GLY A 1 252 ? -14.013 11.475  -17.501  1.00 29.94  ? 245  GLY A CA  1 
ATOM   1860  C C   . GLY A 1 252 ? -14.866 10.597  -16.591  1.00 30.41  ? 245  GLY A C   1 
ATOM   1861  O O   . GLY A 1 252 ? -15.942 11.063  -16.160  1.00 28.15  ? 245  GLY A O   1 
ATOM   1862  N N   . VAL A 1 253 ? -14.399 9.384   -16.270  1.00 29.85  ? 246  VAL A N   1 
ATOM   1863  C CA  . VAL A 1 253 ? -15.127 8.354   -15.459  1.00 29.80  ? 246  VAL A CA  1 
ATOM   1864  C C   . VAL A 1 253 ? -16.429 7.997   -16.168  1.00 26.99  ? 246  VAL A C   1 
ATOM   1865  O O   . VAL A 1 253 ? -17.505 8.390   -15.722  1.00 28.44  ? 246  VAL A O   1 
ATOM   1866  C CB  . VAL A 1 253 ? -15.359 8.795   -14.003  1.00 30.31  ? 246  VAL A CB  1 
ATOM   1867  C CG1 . VAL A 1 253 ? -16.023 7.680   -13.195  1.00 29.23  ? 246  VAL A CG1 1 
ATOM   1868  C CG2 . VAL A 1 253 ? -14.045 9.241   -13.362  1.00 30.86  ? 246  VAL A CG2 1 
ATOM   1869  N N   . ILE A 1 254 ? -16.290 7.313   -17.290  1.00 27.78  ? 247  ILE A N   1 
ATOM   1870  C CA  . ILE A 1 254 ? -17.422 6.924   -18.169  1.00 26.82  ? 247  ILE A CA  1 
ATOM   1871  C C   . ILE A 1 254 ? -17.741 5.480   -17.833  1.00 26.59  ? 247  ILE A C   1 
ATOM   1872  O O   . ILE A 1 254 ? -16.920 4.601   -18.106  1.00 24.39  ? 247  ILE A O   1 
ATOM   1873  C CB  . ILE A 1 254 ? -17.083 7.104   -19.657  1.00 26.25  ? 247  ILE A CB  1 
ATOM   1874  C CG1 . ILE A 1 254 ? -16.565 8.511   -19.973  1.00 26.92  ? 247  ILE A CG1 1 
ATOM   1875  C CG2 . ILE A 1 254 ? -18.287 6.747   -20.505  1.00 25.32  ? 247  ILE A CG2 1 
ATOM   1876  C CD1 . ILE A 1 254 ? -17.444 9.621   -19.447  1.00 27.94  ? 247  ILE A CD1 1 
ATOM   1877  N N   . LEU A 1 255 ? -18.893 5.283   -17.219  1.00 29.16  ? 248  LEU A N   1 
ATOM   1878  C CA  . LEU A 1 255 ? -19.393 3.945   -16.833  1.00 28.67  ? 248  LEU A CA  1 
ATOM   1879  C C   . LEU A 1 255 ? -20.177 3.375   -18.008  1.00 25.92  ? 248  LEU A C   1 
ATOM   1880  O O   . LEU A 1 255 ? -21.067 4.022   -18.562  1.00 24.39  ? 248  LEU A O   1 
ATOM   1881  C CB  . LEU A 1 255 ? -20.247 4.055   -15.564  1.00 28.37  ? 248  LEU A CB  1 
ATOM   1882  C CG  . LEU A 1 255 ? -19.472 3.952   -14.250  1.00 27.77  ? 248  LEU A CG  1 
ATOM   1883  C CD1 . LEU A 1 255 ? -18.472 5.093   -14.105  1.00 28.58  ? 248  LEU A CD1 1 
ATOM   1884  C CD2 . LEU A 1 255 ? -20.427 3.952   -13.081  1.00 29.71  ? 248  LEU A CD2 1 
ATOM   1885  N N   . PRO A 1 256 ? -19.861 2.134   -18.409  1.00 24.15  ? 249  PRO A N   1 
ATOM   1886  C CA  . PRO A 1 256 ? -20.608 1.467   -19.465  1.00 25.24  ? 249  PRO A CA  1 
ATOM   1887  C C   . PRO A 1 256 ? -21.982 1.058   -18.963  1.00 24.42  ? 249  PRO A C   1 
ATOM   1888  O O   . PRO A 1 256 ? -22.205 0.969   -17.770  1.00 22.27  ? 249  PRO A O   1 
ATOM   1889  C CB  . PRO A 1 256 ? -19.751 0.227   -19.738  1.00 26.14  ? 249  PRO A CB  1 
ATOM   1890  C CG  . PRO A 1 256 ? -19.132 -0.080  -18.388  1.00 25.11  ? 249  PRO A CG  1 
ATOM   1891  C CD  . PRO A 1 256 ? -18.820 1.285   -17.824  1.00 24.95  ? 249  PRO A CD  1 
ATOM   1892  N N   . PRO A 1 257 ? -22.952 0.778   -19.853  1.00 27.32  ? 250  PRO A N   1 
ATOM   1893  C CA  . PRO A 1 257 ? -24.251 0.282   -19.423  1.00 26.78  ? 250  PRO A CA  1 
ATOM   1894  C C   . PRO A 1 257 ? -24.014 -1.085  -18.806  1.00 25.97  ? 250  PRO A C   1 
ATOM   1895  O O   . PRO A 1 257 ? -23.071 -1.790  -19.148  1.00 24.32  ? 250  PRO A O   1 
ATOM   1896  C CB  . PRO A 1 257 ? -25.093 0.197   -20.709  1.00 28.20  ? 250  PRO A CB  1 
ATOM   1897  C CG  . PRO A 1 257 ? -24.329 0.993   -21.728  1.00 28.13  ? 250  PRO A CG  1 
ATOM   1898  C CD  . PRO A 1 257 ? -22.878 0.911   -21.311  1.00 28.61  ? 250  PRO A CD  1 
ATOM   1899  N N   . PRO A 1 258 ? -24.869 -1.500  -17.865  1.00 28.53  ? 251  PRO A N   1 
ATOM   1900  C CA  . PRO A 1 258 ? -24.686 -2.797  -17.205  1.00 28.30  ? 251  PRO A CA  1 
ATOM   1901  C C   . PRO A 1 258 ? -24.752 -3.948  -18.225  1.00 26.62  ? 251  PRO A C   1 
ATOM   1902  O O   . PRO A 1 258 ? -25.546 -3.846  -19.174  1.00 25.20  ? 251  PRO A O   1 
ATOM   1903  C CB  . PRO A 1 258 ? -25.821 -2.828  -16.164  1.00 27.95  ? 251  PRO A CB  1 
ATOM   1904  C CG  . PRO A 1 258 ? -26.850 -1.817  -16.670  1.00 28.69  ? 251  PRO A CG  1 
ATOM   1905  C CD  . PRO A 1 258 ? -26.064 -0.762  -17.408  1.00 29.51  ? 251  PRO A CD  1 
ATOM   1906  N N   . GLY A 1 259 ? -23.899 -4.972  -18.048  1.00 24.32  ? 252  GLY A N   1 
ATOM   1907  C CA  . GLY A 1 259 ? -23.810 -6.149  -18.936  1.00 23.44  ? 252  GLY A CA  1 
ATOM   1908  C C   . GLY A 1 259 ? -22.955 -5.926  -20.180  1.00 22.62  ? 252  GLY A C   1 
ATOM   1909  O O   . GLY A 1 259 ? -22.689 -6.931  -20.867  1.00 22.07  ? 252  GLY A O   1 
ATOM   1910  N N   . TYR A 1 260 ? -22.558 -4.676  -20.483  1.00 22.20  ? 253  TYR A N   1 
ATOM   1911  C CA  . TYR A 1 260 ? -21.741 -4.268  -21.660  1.00 21.64  ? 253  TYR A CA  1 
ATOM   1912  C C   . TYR A 1 260 ? -20.474 -5.120  -21.775  1.00 21.35  ? 253  TYR A C   1 
ATOM   1913  O O   . TYR A 1 260 ? -20.186 -5.693  -22.827  1.00 24.49  ? 253  TYR A O   1 
ATOM   1914  C CB  . TYR A 1 260 ? -21.285 -2.813  -21.524  1.00 20.98  ? 253  TYR A CB  1 
ATOM   1915  C CG  . TYR A 1 260 ? -20.361 -2.336  -22.615  1.00 20.03  ? 253  TYR A CG  1 
ATOM   1916  C CD1 . TYR A 1 260 ? -20.774 -2.305  -23.941  1.00 18.96  ? 253  TYR A CD1 1 
ATOM   1917  C CD2 . TYR A 1 260 ? -19.068 -1.922  -22.333  1.00 18.95  ? 253  TYR A CD2 1 
ATOM   1918  C CE1 . TYR A 1 260 ? -19.928 -1.879  -24.953  1.00 17.95  ? 253  TYR A CE1 1 
ATOM   1919  C CE2 . TYR A 1 260 ? -18.213 -1.486  -23.333  1.00 18.14  ? 253  TYR A CE2 1 
ATOM   1920  C CZ  . TYR A 1 260 ? -18.646 -1.466  -24.645  1.00 17.94  ? 253  TYR A CZ  1 
ATOM   1921  O OH  . TYR A 1 260 ? -17.829 -1.021  -25.636  1.00 18.15  ? 253  TYR A OH  1 
ATOM   1922  N N   . LEU A 1 261 ? -19.700 -5.164  -20.710  1.00 20.34  ? 254  LEU A N   1 
ATOM   1923  C CA  . LEU A 1 261 ? -18.421 -5.910  -20.685  1.00 21.18  ? 254  LEU A CA  1 
ATOM   1924  C C   . LEU A 1 261 ? -18.676 -7.394  -21.006  1.00 20.39  ? 254  LEU A C   1 
ATOM   1925  O O   . LEU A 1 261 ? -17.926 -8.002  -21.778  1.00 19.69  ? 254  LEU A O   1 
ATOM   1926  C CB  . LEU A 1 261 ? -17.814 -5.697  -19.298  1.00 21.82  ? 254  LEU A CB  1 
ATOM   1927  C CG  . LEU A 1 261 ? -16.346 -5.287  -19.274  1.00 22.52  ? 254  LEU A CG  1 
ATOM   1928  C CD1 . LEU A 1 261 ? -16.066 -4.130  -20.224  1.00 22.85  ? 254  LEU A CD1 1 
ATOM   1929  C CD2 . LEU A 1 261 ? -15.934 -4.925  -17.858  1.00 22.41  ? 254  LEU A CD2 1 
ATOM   1930  N N   . THR A 1 262 ? -19.728 -7.963  -20.435  1.00 20.51  ? 255  THR A N   1 
ATOM   1931  C CA  . THR A 1 262 ? -20.094 -9.386  -20.611  1.00 20.13  ? 255  THR A CA  1 
ATOM   1932  C C   . THR A 1 262 ? -20.430 -9.621  -22.075  1.00 19.77  ? 255  THR A C   1 
ATOM   1933  O O   . THR A 1 262 ? -20.050 -10.666 -22.617  1.00 20.46  ? 255  THR A O   1 
ATOM   1934  C CB  . THR A 1 262 ? -21.270 -9.753  -19.715  1.00 21.12  ? 255  THR A CB  1 
ATOM   1935  O OG1 . THR A 1 262 ? -20.825 -9.658  -18.357  1.00 21.55  ? 255  THR A OG1 1 
ATOM   1936  C CG2 . THR A 1 262 ? -21.783 -11.139 -20.022  1.00 21.67  ? 255  THR A CG2 1 
ATOM   1937  N N   . ALA A 1 263 ? -21.126 -8.666  -22.681  1.00 20.86  ? 256  ALA A N   1 
ATOM   1938  C CA  . ALA A 1 263 ? -21.568 -8.703  -24.102  1.00 19.99  ? 256  ALA A CA  1 
ATOM   1939  C C   . ALA A 1 263 ? -20.343 -8.598  -25.017  1.00 19.04  ? 256  ALA A C   1 
ATOM   1940  O O   . ALA A 1 263 ? -20.266 -9.357  -25.994  1.00 18.79  ? 256  ALA A O   1 
ATOM   1941  C CB  . ALA A 1 263 ? -22.577 -7.601  -24.377  1.00 19.28  ? 256  ALA A CB  1 
ATOM   1942  N N   . VAL A 1 264 ? -19.411 -7.701  -24.704  1.00 18.57  ? 257  VAL A N   1 
ATOM   1943  C CA  . VAL A 1 264 ? -18.135 -7.536  -25.462  1.00 18.90  ? 257  VAL A CA  1 
ATOM   1944  C C   . VAL A 1 264 ? -17.394 -8.875  -25.465  1.00 18.54  ? 257  VAL A C   1 
ATOM   1945  O O   . VAL A 1 264 ? -16.866 -9.239  -26.532  1.00 19.62  ? 257  VAL A O   1 
ATOM   1946  C CB  . VAL A 1 264 ? -17.268 -6.397  -24.895  1.00 19.25  ? 257  VAL A CB  1 
ATOM   1947  C CG1 . VAL A 1 264 ? -15.876 -6.400  -25.493  1.00 19.83  ? 257  VAL A CG1 1 
ATOM   1948  C CG2 . VAL A 1 264 ? -17.924 -5.041  -25.091  1.00 19.64  ? 257  VAL A CG2 1 
ATOM   1949  N N   . ARG A 1 265 ? -17.387 -9.581  -24.334  1.00 18.34  ? 258  ARG A N   1 
ATOM   1950  C CA  . ARG A 1 265 ? -16.721 -10.900 -24.184  1.00 20.54  ? 258  ARG A CA  1 
ATOM   1951  C C   . ARG A 1 265 ? -17.394 -11.917 -25.116  1.00 22.32  ? 258  ARG A C   1 
ATOM   1952  O O   . ARG A 1 265 ? -16.674 -12.627 -25.825  1.00 23.06  ? 258  ARG A O   1 
ATOM   1953  C CB  . ARG A 1 265 ? -16.733 -11.356 -22.716  1.00 21.03  ? 258  ARG A CB  1 
ATOM   1954  C CG  . ARG A 1 265 ? -16.437 -12.838 -22.497  1.00 21.51  ? 258  ARG A CG  1 
ATOM   1955  C CD  . ARG A 1 265 ? -14.979 -13.255 -22.583  1.00 22.21  ? 258  ARG A CD  1 
ATOM   1956  N NE  . ARG A 1 265 ? -14.400 -13.343 -23.918  1.00 21.95  ? 258  ARG A NE  1 
ATOM   1957  C CZ  . ARG A 1 265 ? -13.094 -13.421 -24.174  1.00 22.10  ? 258  ARG A CZ  1 
ATOM   1958  N NH1 . ARG A 1 265 ? -12.211 -13.410 -23.186  1.00 23.09  ? 258  ARG A NH1 1 
ATOM   1959  N NH2 . ARG A 1 265 ? -12.665 -13.479 -25.423  1.00 22.30  ? 258  ARG A NH2 1 
ATOM   1960  N N   . LYS A 1 266 ? -18.723 -12.019 -25.098  1.00 25.78  ? 259  LYS A N   1 
ATOM   1961  C CA  . LYS A 1 266 ? -19.456 -12.959 -25.986  1.00 26.33  ? 259  LYS A CA  1 
ATOM   1962  C C   . LYS A 1 266 ? -19.214 -12.575 -27.453  1.00 27.63  ? 259  LYS A C   1 
ATOM   1963  O O   . LYS A 1 266 ? -19.059 -13.485 -28.306  1.00 28.05  ? 259  LYS A O   1 
ATOM   1964  C CB  . LYS A 1 266 ? -20.955 -12.926 -25.707  1.00 27.02  ? 259  LYS A CB  1 
ATOM   1965  C CG  . LYS A 1 266 ? -21.408 -13.462 -24.378  1.00 27.66  ? 259  LYS A CG  1 
ATOM   1966  C CD  . LYS A 1 266 ? -22.900 -13.526 -24.395  1.00 32.98  ? 259  LYS A CD  1 
ATOM   1967  C CE  . LYS A 1 266 ? -23.517 -13.281 -23.040  1.00 37.13  ? 259  LYS A CE  1 
ATOM   1968  N NZ  . LYS A 1 266 ? -23.005 -14.265 -22.057  1.00 41.38  ? 259  LYS A NZ  1 
ATOM   1969  N N   . LEU A 1 267 ? -19.218 -11.270 -27.746  1.00 26.60  ? 260  LEU A N   1 
ATOM   1970  C CA  . LEU A 1 267 ? -19.033 -10.712 -29.110  1.00 25.02  ? 260  LEU A CA  1 
ATOM   1971  C C   . LEU A 1 267 ? -17.631 -11.094 -29.608  1.00 25.39  ? 260  LEU A C   1 
ATOM   1972  O O   . LEU A 1 267 ? -17.535 -11.628 -30.721  1.00 24.11  ? 260  LEU A O   1 
ATOM   1973  C CB  . LEU A 1 267 ? -19.213 -9.196  -29.027  1.00 25.08  ? 260  LEU A CB  1 
ATOM   1974  C CG  . LEU A 1 267 ? -19.279 -8.463  -30.358  1.00 25.98  ? 260  LEU A CG  1 
ATOM   1975  C CD1 . LEU A 1 267 ? -20.644 -8.641  -30.968  1.00 27.91  ? 260  LEU A CD1 1 
ATOM   1976  C CD2 . LEU A 1 267 ? -19.025 -6.983  -30.187  1.00 26.34  ? 260  LEU A CD2 1 
ATOM   1977  N N   . CYS A 1 268 ? -16.592 -10.872 -28.792  1.00 24.62  ? 261  CYS A N   1 
ATOM   1978  C CA  . CYS A 1 268 ? -15.202 -11.326 -29.066  1.00 25.37  ? 261  CYS A CA  1 
ATOM   1979  C C   . CYS A 1 268 ? -15.188 -12.847 -29.288  1.00 24.79  ? 261  CYS A C   1 
ATOM   1980  O O   . CYS A 1 268 ? -14.568 -13.298 -30.260  1.00 24.92  ? 261  CYS A O   1 
ATOM   1981  C CB  . CYS A 1 268 ? -14.236 -10.923 -27.952  1.00 25.87  ? 261  CYS A CB  1 
ATOM   1982  S SG  . CYS A 1 268 ? -13.854 -9.150  -27.910  1.00 27.04  ? 261  CYS A SG  1 
ATOM   1983  N N   . ASP A 1 269 ? -15.844 -13.620 -28.433  1.00 24.65  ? 262  ASP A N   1 
ATOM   1984  C CA  . ASP A 1 269 ? -15.878 -15.101 -28.552  1.00 27.22  ? 262  ASP A CA  1 
ATOM   1985  C C   . ASP A 1 269 ? -16.468 -15.503 -29.909  1.00 29.35  ? 262  ASP A C   1 
ATOM   1986  O O   . ASP A 1 269 ? -15.969 -16.472 -30.522  1.00 30.31  ? 262  ASP A O   1 
ATOM   1987  C CB  . ASP A 1 269 ? -16.699 -15.732 -27.431  1.00 29.64  ? 262  ASP A CB  1 
ATOM   1988  C CG  . ASP A 1 269 ? -15.959 -15.776 -26.110  1.00 31.39  ? 262  ASP A CG  1 
ATOM   1989  O OD1 . ASP A 1 269 ? -14.696 -15.753 -26.149  1.00 33.51  ? 262  ASP A OD1 1 
ATOM   1990  O OD2 . ASP A 1 269 ? -16.655 -15.838 -25.058  1.00 33.40  ? 262  ASP A OD2 1 
ATOM   1991  N N   . GLU A 1 270 ? -17.515 -14.806 -30.344  1.00 28.13  ? 263  GLU A N   1 
ATOM   1992  C CA  . GLU A 1 270 ? -18.285 -15.162 -31.561  1.00 29.21  ? 263  GLU A CA  1 
ATOM   1993  C C   . GLU A 1 270 ? -17.438 -14.924 -32.822  1.00 27.26  ? 263  GLU A C   1 
ATOM   1994  O O   . GLU A 1 270 ? -17.459 -15.792 -33.706  1.00 25.54  ? 263  GLU A O   1 
ATOM   1995  C CB  . GLU A 1 270 ? -19.579 -14.346 -31.582  1.00 31.63  ? 263  GLU A CB  1 
ATOM   1996  C CG  . GLU A 1 270 ? -20.363 -14.442 -32.868  1.00 31.79  ? 263  GLU A CG  1 
ATOM   1997  C CD  . GLU A 1 270 ? -21.671 -13.660 -32.832  1.00 34.50  ? 263  GLU A CD  1 
ATOM   1998  O OE1 . GLU A 1 270 ? -22.212 -13.436 -31.712  1.00 35.78  ? 263  GLU A OE1 1 
ATOM   1999  O OE2 . GLU A 1 270 ? -22.162 -13.283 -33.931  1.00 34.07  ? 263  GLU A OE2 1 
ATOM   2000  N N   . PHE A 1 271 ? -16.735 -13.789 -32.901  1.00 25.62  ? 264  PHE A N   1 
ATOM   2001  C CA  . PHE A 1 271 ? -15.934 -13.355 -34.081  1.00 23.46  ? 264  PHE A CA  1 
ATOM   2002  C C   . PHE A 1 271 ? -14.494 -13.890 -34.025  1.00 22.56  ? 264  PHE A C   1 
ATOM   2003  O O   . PHE A 1 271 ? -13.724 -13.602 -34.963  1.00 24.77  ? 264  PHE A O   1 
ATOM   2004  C CB  . PHE A 1 271 ? -15.940 -11.830 -34.180  1.00 21.43  ? 264  PHE A CB  1 
ATOM   2005  C CG  . PHE A 1 271 ? -17.190 -11.278 -34.793  1.00 19.80  ? 264  PHE A CG  1 
ATOM   2006  C CD1 . PHE A 1 271 ? -18.312 -11.044 -34.016  1.00 19.59  ? 264  PHE A CD1 1 
ATOM   2007  C CD2 . PHE A 1 271 ? -17.269 -11.048 -36.160  1.00 19.68  ? 264  PHE A CD2 1 
ATOM   2008  C CE1 . PHE A 1 271 ? -19.488 -10.567 -34.589  1.00 19.34  ? 264  PHE A CE1 1 
ATOM   2009  C CE2 . PHE A 1 271 ? -18.444 -10.571 -36.738  1.00 19.69  ? 264  PHE A CE2 1 
ATOM   2010  C CZ  . PHE A 1 271 ? -19.555 -10.325 -35.951  1.00 19.61  ? 264  PHE A CZ  1 
ATOM   2011  N N   . GLY A 1 272 ? -14.125 -14.618 -32.972  1.00 24.35  ? 265  GLY A N   1 
ATOM   2012  C CA  . GLY A 1 272 ? -12.762 -15.146 -32.733  1.00 24.05  ? 265  GLY A CA  1 
ATOM   2013  C C   . GLY A 1 272 ? -11.714 -14.059 -32.517  1.00 23.66  ? 265  GLY A C   1 
ATOM   2014  O O   . GLY A 1 272 ? -10.557 -14.284 -32.901  1.00 23.79  ? 265  GLY A O   1 
ATOM   2015  N N   . ALA A 1 273 ? -12.091 -12.923 -31.924  1.00 23.82  ? 266  ALA A N   1 
ATOM   2016  C CA  . ALA A 1 273 ? -11.194 -11.804 -31.541  1.00 22.96  ? 266  ALA A CA  1 
ATOM   2017  C C   . ALA A 1 273 ? -10.770 -11.962 -30.079  1.00 20.99  ? 266  ALA A C   1 
ATOM   2018  O O   . ALA A 1 273 ? -11.569 -12.492 -29.271  1.00 22.24  ? 266  ALA A O   1 
ATOM   2019  C CB  . ALA A 1 273 ? -11.883 -10.478 -31.763  1.00 24.27  ? 266  ALA A CB  1 
ATOM   2020  N N   . LEU A 1 274 ? -9.558  -11.506 -29.739  1.00 20.70  ? 267  LEU A N   1 
ATOM   2021  C CA  . LEU A 1 274 ? -9.083  -11.501 -28.328  1.00 19.53  ? 267  LEU A CA  1 
ATOM   2022  C C   . LEU A 1 274 ? -9.645  -10.267 -27.616  1.00 18.80  ? 267  LEU A C   1 
ATOM   2023  O O   . LEU A 1 274 ? -9.737  -9.186  -28.217  1.00 17.32  ? 267  LEU A O   1 
ATOM   2024  C CB  . LEU A 1 274 ? -7.557  -11.542 -28.258  1.00 19.07  ? 267  LEU A CB  1 
ATOM   2025  C CG  . LEU A 1 274 ? -6.910  -12.782 -28.878  1.00 19.89  ? 267  LEU A CG  1 
ATOM   2026  C CD1 . LEU A 1 274 ? -5.395  -12.730 -28.766  1.00 19.59  ? 267  LEU A CD1 1 
ATOM   2027  C CD2 . LEU A 1 274 ? -7.419  -14.058 -28.233  1.00 19.51  ? 267  LEU A CD2 1 
ATOM   2028  N N   . MET A 1 275 ? -10.015 -10.454 -26.360  1.00 19.35  ? 268  MET A N   1 
ATOM   2029  C CA  . MET A 1 275 ? -10.489 -9.370  -25.479  1.00 19.35  ? 268  MET A CA  1 
ATOM   2030  C C   . MET A 1 275 ? -9.329  -8.874  -24.616  1.00 18.31  ? 268  MET A C   1 
ATOM   2031  O O   . MET A 1 275 ? -8.794  -9.646  -23.799  1.00 17.18  ? 268  MET A O   1 
ATOM   2032  C CB  . MET A 1 275 ? -11.636 -9.856  -24.599  1.00 20.19  ? 268  MET A CB  1 
ATOM   2033  C CG  . MET A 1 275 ? -12.182 -8.741  -23.737  1.00 21.41  ? 268  MET A CG  1 
ATOM   2034  S SD  . MET A 1 275 ? -13.719 -9.191  -22.930  1.00 21.89  ? 268  MET A SD  1 
ATOM   2035  C CE  . MET A 1 275 ? -14.088 -7.623  -22.145  1.00 22.72  ? 268  MET A CE  1 
ATOM   2036  N N   . ILE A 1 276 ? -8.957  -7.615  -24.809  1.00 18.65  ? 269  ILE A N   1 
ATOM   2037  C CA  . ILE A 1 276 ? -7.934  -6.932  -23.974  1.00 19.90  ? 269  ILE A CA  1 
ATOM   2038  C C   . ILE A 1 276 ? -8.647  -5.942  -23.055  1.00 20.07  ? 269  ILE A C   1 
ATOM   2039  O O   . ILE A 1 276 ? -9.256  -4.996  -23.567  1.00 19.27  ? 269  ILE A O   1 
ATOM   2040  C CB  . ILE A 1 276 ? -6.892  -6.223  -24.848  1.00 19.64  ? 269  ILE A CB  1 
ATOM   2041  C CG1 . ILE A 1 276 ? -6.214  -7.190  -25.810  1.00 19.77  ? 269  ILE A CG1 1 
ATOM   2042  C CG2 . ILE A 1 276 ? -5.880  -5.499  -23.980  1.00 19.69  ? 269  ILE A CG2 1 
ATOM   2043  C CD1 . ILE A 1 276 ? -5.218  -6.522  -26.731  1.00 19.75  ? 269  ILE A CD1 1 
ATOM   2044  N N   . LEU A 1 277 ? -8.499  -6.134  -21.747  1.00 21.88  ? 270  LEU A N   1 
ATOM   2045  C CA  . LEU A 1 277 ? -8.958  -5.170  -20.721  1.00 21.58  ? 270  LEU A CA  1 
ATOM   2046  C C   . LEU A 1 277 ? -7.771  -4.376  -20.185  1.00 19.88  ? 270  LEU A C   1 
ATOM   2047  O O   . LEU A 1 277 ? -6.870  -4.966  -19.616  1.00 17.74  ? 270  LEU A O   1 
ATOM   2048  C CB  . LEU A 1 277 ? -9.669  -5.915  -19.597  1.00 22.92  ? 270  LEU A CB  1 
ATOM   2049  C CG  . LEU A 1 277 ? -11.188 -5.952  -19.737  1.00 24.59  ? 270  LEU A CG  1 
ATOM   2050  C CD1 . LEU A 1 277 ? -11.810 -6.379  -18.433  1.00 28.11  ? 270  LEU A CD1 1 
ATOM   2051  C CD2 . LEU A 1 277 ? -11.760 -4.607  -20.161  1.00 24.11  ? 270  LEU A CD2 1 
ATOM   2052  N N   . ASP A 1 278 ? -7.828  -3.061  -20.373  1.00 20.67  ? 271  ASP A N   1 
ATOM   2053  C CA  . ASP A 1 278 ? -6.882  -2.059  -19.828  1.00 21.61  ? 271  ASP A CA  1 
ATOM   2054  C C   . ASP A 1 278 ? -7.338  -1.640  -18.424  1.00 21.69  ? 271  ASP A C   1 
ATOM   2055  O O   . ASP A 1 278 ? -8.117  -0.664  -18.312  1.00 23.14  ? 271  ASP A O   1 
ATOM   2056  C CB  . ASP A 1 278 ? -6.779  -0.875  -20.792  1.00 22.63  ? 271  ASP A CB  1 
ATOM   2057  C CG  . ASP A 1 278 ? -5.807  0.197   -20.344  1.00 24.55  ? 271  ASP A CG  1 
ATOM   2058  O OD1 . ASP A 1 278 ? -5.314  0.098   -19.205  1.00 27.26  ? 271  ASP A OD1 1 
ATOM   2059  O OD2 . ASP A 1 278 ? -5.527  1.097   -21.141  1.00 25.99  ? 271  ASP A OD2 1 
ATOM   2060  N N   . GLU A 1 279 ? -6.876  -2.346  -17.390  1.00 20.58  ? 272  GLU A N   1 
ATOM   2061  C CA  . GLU A 1 279 ? -7.192  -2.021  -15.968  1.00 20.25  ? 272  GLU A CA  1 
ATOM   2062  C C   . GLU A 1 279 ? -6.016  -1.285  -15.324  1.00 20.42  ? 272  GLU A C   1 
ATOM   2063  O O   . GLU A 1 279 ? -5.875  -1.344  -14.105  1.00 17.90  ? 272  GLU A O   1 
ATOM   2064  C CB  . GLU A 1 279 ? -7.525  -3.294  -15.204  1.00 19.72  ? 272  GLU A CB  1 
ATOM   2065  C CG  . GLU A 1 279 ? -8.879  -3.811  -15.570  1.00 20.17  ? 272  GLU A CG  1 
ATOM   2066  C CD  . GLU A 1 279 ? -9.838  -4.017  -14.419  1.00 20.59  ? 272  GLU A CD  1 
ATOM   2067  O OE1 . GLU A 1 279 ? -9.732  -3.317  -13.373  1.00 19.38  ? 272  GLU A OE1 1 
ATOM   2068  O OE2 . GLU A 1 279 ? -10.711 -4.889  -14.587  1.00 23.99  ? 272  GLU A OE2 1 
ATOM   2069  N N   . VAL A 1 280 ? -5.203  -0.619  -16.141  1.00 21.14  ? 273  VAL A N   1 
ATOM   2070  C CA  . VAL A 1 280 ? -4.100  0.237   -15.643  1.00 23.80  ? 273  VAL A CA  1 
ATOM   2071  C C   . VAL A 1 280 ? -4.656  1.178   -14.571  1.00 23.17  ? 273  VAL A C   1 
ATOM   2072  O O   . VAL A 1 280 ? -3.981  1.364   -13.548  1.00 22.76  ? 273  VAL A O   1 
ATOM   2073  C CB  . VAL A 1 280 ? -3.424  0.999   -16.793  1.00 23.11  ? 273  VAL A CB  1 
ATOM   2074  C CG1 . VAL A 1 280 ? -2.582  2.161   -16.293  1.00 23.05  ? 273  VAL A CG1 1 
ATOM   2075  C CG2 . VAL A 1 280 ? -2.581  0.056   -17.617  1.00 23.22  ? 273  VAL A CG2 1 
ATOM   2076  N N   . GLN A 1 281 ? -5.817  1.771   -14.804  1.00 24.73  ? 274  GLN A N   1 
ATOM   2077  C CA  . GLN A 1 281 ? -6.323  2.811   -13.884  1.00 29.15  ? 274  GLN A CA  1 
ATOM   2078  C C   . GLN A 1 281 ? -7.467  2.304   -12.996  1.00 29.58  ? 274  GLN A C   1 
ATOM   2079  O O   . GLN A 1 281 ? -7.612  2.885   -11.882  1.00 30.08  ? 274  GLN A O   1 
ATOM   2080  C CB  . GLN A 1 281 ? -6.754  4.055   -14.633  1.00 33.47  ? 274  GLN A CB  1 
ATOM   2081  C CG  . GLN A 1 281 ? -6.986  5.210   -13.675  1.00 35.89  ? 274  GLN A CG  1 
ATOM   2082  C CD  . GLN A 1 281 ? -7.094  6.524   -14.397  1.00 40.26  ? 274  GLN A CD  1 
ATOM   2083  O OE1 . GLN A 1 281 ? -7.571  7.500   -13.824  1.00 40.58  ? 274  GLN A OE1 1 
ATOM   2084  N NE2 . GLN A 1 281 ? -6.662  6.551   -15.655  1.00 41.33  ? 274  GLN A NE2 1 
ATOM   2085  N N   . THR A 1 282 ? -8.170  1.235   -13.384  1.00 27.68  ? 275  THR A N   1 
ATOM   2086  C CA  . THR A 1 282 ? -9.285  0.664   -12.578  1.00 28.41  ? 275  THR A CA  1 
ATOM   2087  C C   . THR A 1 282 ? -8.833  -0.518  -11.717  1.00 27.10  ? 275  THR A C   1 
ATOM   2088  O O   . THR A 1 282 ? -9.669  -1.049  -10.985  1.00 26.84  ? 275  THR A O   1 
ATOM   2089  C CB  . THR A 1 282 ? -10.416 0.211   -13.488  1.00 29.39  ? 275  THR A CB  1 
ATOM   2090  O OG1 . THR A 1 282 ? -9.905  -0.825  -14.335  1.00 28.89  ? 275  THR A OG1 1 
ATOM   2091  C CG2 . THR A 1 282 ? -10.955 1.371   -14.292  1.00 32.82  ? 275  THR A CG2 1 
ATOM   2092  N N   . GLY A 1 283 ? -7.563  -0.908  -11.786  1.00 24.43  ? 276  GLY A N   1 
ATOM   2093  C CA  . GLY A 1 283 ? -7.053  -2.093  -11.081  1.00 24.05  ? 276  GLY A CA  1 
ATOM   2094  C C   . GLY A 1 283 ? -6.604  -1.782  -9.649   1.00 24.75  ? 276  GLY A C   1 
ATOM   2095  O O   . GLY A 1 283 ? -6.578  -0.589  -9.215   1.00 24.17  ? 276  GLY A O   1 
ATOM   2096  N N   . MET A 1 284 ? -6.256  -2.840  -8.925   1.00 23.91  ? 277  MET A N   1 
ATOM   2097  C CA  . MET A 1 284 ? -5.738  -2.774  -7.543   1.00 24.85  ? 277  MET A CA  1 
ATOM   2098  C C   . MET A 1 284 ? -6.773  -2.092  -6.619   1.00 24.98  ? 277  MET A C   1 
ATOM   2099  O O   . MET A 1 284 ? -6.391  -1.218  -5.817   1.00 24.54  ? 277  MET A O   1 
ATOM   2100  C CB  . MET A 1 284 ? -4.388  -2.044  -7.528   1.00 24.34  ? 277  MET A CB  1 
ATOM   2101  C CG  . MET A 1 284 ? -3.384  -2.573  -8.567   1.00 25.23  ? 277  MET A CG  1 
ATOM   2102  S SD  . MET A 1 284 ? -3.469  -4.373  -8.888   1.00 24.28  ? 277  MET A SD  1 
ATOM   2103  C CE  . MET A 1 284 ? -2.916  -5.047  -7.329   1.00 22.68  ? 277  MET A CE  1 
ATOM   2104  N N   . GLY A 1 285 ? -8.041  -2.494  -6.725   1.00 24.58  ? 278  GLY A N   1 
ATOM   2105  C CA  . GLY A 1 285 ? -9.087  -2.233  -5.721   1.00 23.79  ? 278  GLY A CA  1 
ATOM   2106  C C   . GLY A 1 285 ? -9.825  -0.914  -5.925   1.00 23.80  ? 278  GLY A C   1 
ATOM   2107  O O   . GLY A 1 285 ? -10.794 -0.681  -5.177   1.00 20.55  ? 278  GLY A O   1 
ATOM   2108  N N   . ARG A 1 286 ? -9.404  -0.060  -6.871   1.00 24.74  ? 279  ARG A N   1 
ATOM   2109  C CA  . ARG A 1 286 ? -9.893  1.348   -6.932   1.00 25.35  ? 279  ARG A CA  1 
ATOM   2110  C C   . ARG A 1 286 ? -11.430 1.442   -7.132   1.00 25.07  ? 279  ARG A C   1 
ATOM   2111  O O   . ARG A 1 286 ? -12.025 2.431   -6.642   1.00 25.05  ? 279  ARG A O   1 
ATOM   2112  C CB  . ARG A 1 286 ? -9.172  2.160   -8.007   1.00 25.03  ? 279  ARG A CB  1 
ATOM   2113  C CG  . ARG A 1 286 ? -9.807  3.531   -8.174   1.00 25.85  ? 279  ARG A CG  1 
ATOM   2114  C CD  . ARG A 1 286 ? -8.861  4.608   -8.595   1.00 26.65  ? 279  ARG A CD  1 
ATOM   2115  N NE  . ARG A 1 286 ? -7.750  4.786   -7.672   1.00 27.75  ? 279  ARG A NE  1 
ATOM   2116  C CZ  . ARG A 1 286 ? -7.763  5.575   -6.604   1.00 26.55  ? 279  ARG A CZ  1 
ATOM   2117  N NH1 . ARG A 1 286 ? -8.846  6.263   -6.271   1.00 25.96  ? 279  ARG A NH1 1 
ATOM   2118  N NH2 . ARG A 1 286 ? -6.673  5.664   -5.876   1.00 26.55  ? 279  ARG A NH2 1 
ATOM   2119  N N   . THR A 1 287 ? -12.078 0.497   -7.817   1.00 24.02  ? 280  THR A N   1 
ATOM   2120  C CA  . THR A 1 287 ? -13.533 0.599   -8.141   1.00 24.22  ? 280  THR A CA  1 
ATOM   2121  C C   . THR A 1 287 ? -14.380 -0.141  -7.115   1.00 21.79  ? 280  THR A C   1 
ATOM   2122  O O   . THR A 1 287 ? -15.593 -0.170  -7.284   1.00 21.56  ? 280  THR A O   1 
ATOM   2123  C CB  . THR A 1 287 ? -13.866 0.053   -9.534   1.00 24.36  ? 280  THR A CB  1 
ATOM   2124  O OG1 . THR A 1 287 ? -13.611 -1.356  -9.550   1.00 24.64  ? 280  THR A OG1 1 
ATOM   2125  C CG2 . THR A 1 287 ? -13.055 0.755   -10.600  1.00 26.14  ? 280  THR A CG2 1 
ATOM   2126  N N   . GLY A 1 288 ? -13.761 -0.730  -6.104   1.00 21.75  ? 281  GLY A N   1 
ATOM   2127  C CA  . GLY A 1 288 ? -14.493 -1.487  -5.075   1.00 22.92  ? 281  GLY A CA  1 
ATOM   2128  C C   . GLY A 1 288 ? -14.246 -2.974  -5.208   1.00 23.22  ? 281  GLY A C   1 
ATOM   2129  O O   . GLY A 1 288 ? -14.682 -3.722  -4.319   1.00 25.62  ? 281  GLY A O   1 
ATOM   2130  N N   . LYS A 1 289 ? -13.579 -3.404  -6.276   1.00 21.51  ? 282  LYS A N   1 
ATOM   2131  C CA  . LYS A 1 289 ? -13.039 -4.773  -6.374   1.00 22.66  ? 282  LYS A CA  1 
ATOM   2132  C C   . LYS A 1 289 ? -11.578 -4.667  -6.787   1.00 21.82  ? 282  LYS A C   1 
ATOM   2133  O O   . LYS A 1 289 ? -11.160 -3.576  -7.227   1.00 21.34  ? 282  LYS A O   1 
ATOM   2134  C CB  . LYS A 1 289 ? -13.814 -5.576  -7.407   1.00 26.42  ? 282  LYS A CB  1 
ATOM   2135  C CG  . LYS A 1 289 ? -15.305 -5.717  -7.159   1.00 28.50  ? 282  LYS A CG  1 
ATOM   2136  C CD  . LYS A 1 289 ? -15.704 -6.959  -6.429   1.00 31.87  ? 282  LYS A CD  1 
ATOM   2137  C CE  . LYS A 1 289 ? -17.120 -7.375  -6.801   1.00 35.83  ? 282  LYS A CE  1 
ATOM   2138  N NZ  . LYS A 1 289 ? -17.619 -8.436  -5.906   1.00 37.88  ? 282  LYS A NZ  1 
ATOM   2139  N N   . MET A 1 290 ? -10.837 -5.767  -6.655   1.00 21.65  ? 283  MET A N   1 
ATOM   2140  C CA  . MET A 1 290 ? -9.399  -5.813  -7.007   1.00 21.92  ? 283  MET A CA  1 
ATOM   2141  C C   . MET A 1 290 ? -9.255  -5.390  -8.477   1.00 20.32  ? 283  MET A C   1 
ATOM   2142  O O   . MET A 1 290 ? -8.368  -4.588  -8.765   1.00 19.49  ? 283  MET A O   1 
ATOM   2143  C CB  . MET A 1 290 ? -8.815  -7.213  -6.778   1.00 22.20  ? 283  MET A CB  1 
ATOM   2144  C CG  . MET A 1 290 ? -7.291  -7.261  -6.957   1.00 22.45  ? 283  MET A CG  1 
ATOM   2145  S SD  . MET A 1 290 ? -6.405  -6.049  -5.922   1.00 21.69  ? 283  MET A SD  1 
ATOM   2146  C CE  . MET A 1 290 ? -6.639  -6.733  -4.287   1.00 21.78  ? 283  MET A CE  1 
ATOM   2147  N N   . PHE A 1 291 ? -10.145 -5.866  -9.350   1.00 20.33  ? 284  PHE A N   1 
ATOM   2148  C CA  . PHE A 1 291 ? -10.242 -5.451  -10.779  1.00 21.54  ? 284  PHE A CA  1 
ATOM   2149  C C   . PHE A 1 291 ? -11.709 -5.149  -11.117  1.00 21.63  ? 284  PHE A C   1 
ATOM   2150  O O   . PHE A 1 291 ? -12.609 -5.851  -10.642  1.00 21.32  ? 284  PHE A O   1 
ATOM   2151  C CB  . PHE A 1 291 ? -9.701  -6.546  -11.701  1.00 21.34  ? 284  PHE A CB  1 
ATOM   2152  C CG  . PHE A 1 291 ? -8.418  -7.173  -11.229  1.00 23.97  ? 284  PHE A CG  1 
ATOM   2153  C CD1 . PHE A 1 291 ? -7.248  -6.433  -11.191  1.00 24.82  ? 284  PHE A CD1 1 
ATOM   2154  C CD2 . PHE A 1 291 ? -8.381  -8.496  -10.806  1.00 25.63  ? 284  PHE A CD2 1 
ATOM   2155  C CE1 . PHE A 1 291 ? -6.060  -7.013  -10.761  1.00 27.07  ? 284  PHE A CE1 1 
ATOM   2156  C CE2 . PHE A 1 291 ? -7.198  -9.065  -10.361  1.00 27.15  ? 284  PHE A CE2 1 
ATOM   2157  C CZ  . PHE A 1 291 ? -6.034  -8.324  -10.333  1.00 27.54  ? 284  PHE A CZ  1 
ATOM   2158  N N   . ALA A 1 292 ? -11.953 -4.120  -11.918  1.00 20.38  ? 285  ALA A N   1 
ATOM   2159  C CA  . ALA A 1 292 ? -13.310 -3.728  -12.336  1.00 21.13  ? 285  ALA A CA  1 
ATOM   2160  C C   . ALA A 1 292 ? -13.965 -4.863  -13.130  1.00 22.83  ? 285  ALA A C   1 
ATOM   2161  O O   . ALA A 1 292 ? -15.181 -4.882  -13.152  1.00 21.64  ? 285  ALA A O   1 
ATOM   2162  C CB  . ALA A 1 292 ? -13.275 -2.444  -13.126  1.00 21.34  ? 285  ALA A CB  1 
ATOM   2163  N N   . CYS A 1 293 ? -13.209 -5.786  -13.740  1.00 24.18  ? 286  CYS A N   1 
ATOM   2164  C CA  . CYS A 1 293 ? -13.780 -6.926  -14.507  1.00 25.20  ? 286  CYS A CA  1 
ATOM   2165  C C   . CYS A 1 293 ? -14.454 -7.921  -13.549  1.00 25.80  ? 286  CYS A C   1 
ATOM   2166  O O   . CYS A 1 293 ? -15.222 -8.761  -14.019  1.00 28.07  ? 286  CYS A O   1 
ATOM   2167  C CB  . CYS A 1 293 ? -12.746 -7.611  -15.392  1.00 25.25  ? 286  CYS A CB  1 
ATOM   2168  S SG  . CYS A 1 293 ? -11.444 -8.524  -14.517  1.00 29.99  ? 286  CYS A SG  1 
ATOM   2169  N N   . GLU A 1 294 ? -14.235 -7.801  -12.248  1.00 28.13  ? 287  GLU A N   1 
ATOM   2170  C CA  . GLU A 1 294 ? -14.848 -8.700  -11.228  1.00 29.04  ? 287  GLU A CA  1 
ATOM   2171  C C   . GLU A 1 294 ? -16.303 -8.313  -10.955  1.00 27.58  ? 287  GLU A C   1 
ATOM   2172  O O   . GLU A 1 294 ? -17.050 -9.217  -10.553  1.00 27.67  ? 287  GLU A O   1 
ATOM   2173  C CB  . GLU A 1 294 ? -14.019 -8.709  -9.939   1.00 30.18  ? 287  GLU A CB  1 
ATOM   2174  C CG  . GLU A 1 294 ? -12.663 -9.348  -10.125  1.00 31.25  ? 287  GLU A CG  1 
ATOM   2175  C CD  . GLU A 1 294 ? -11.759 -9.384  -8.904   1.00 34.03  ? 287  GLU A CD  1 
ATOM   2176  O OE1 . GLU A 1 294 ? -11.964 -8.587  -7.963   1.00 34.25  ? 287  GLU A OE1 1 
ATOM   2177  O OE2 . GLU A 1 294 ? -10.834 -10.213 -8.906   1.00 37.99  ? 287  GLU A OE2 1 
ATOM   2178  N N   . HIS A 1 295 ? -16.694 -7.052  -11.183  1.00 28.41  ? 288  HIS A N   1 
ATOM   2179  C CA  . HIS A 1 295 ? -18.105 -6.576  -11.051  1.00 28.66  ? 288  HIS A CA  1 
ATOM   2180  C C   . HIS A 1 295 ? -19.035 -7.469  -11.870  1.00 28.25  ? 288  HIS A C   1 
ATOM   2181  O O   . HIS A 1 295 ? -20.083 -7.840  -11.337  1.00 31.07  ? 288  HIS A O   1 
ATOM   2182  C CB  . HIS A 1 295 ? -18.270 -5.096  -11.434  1.00 27.51  ? 288  HIS A CB  1 
ATOM   2183  C CG  . HIS A 1 295 ? -17.585 -4.163  -10.493  1.00 28.62  ? 288  HIS A CG  1 
ATOM   2184  N ND1 . HIS A 1 295 ? -17.938 -4.055  -9.149   1.00 30.43  ? 288  HIS A ND1 1 
ATOM   2185  C CD2 . HIS A 1 295 ? -16.540 -3.328  -10.679  1.00 29.95  ? 288  HIS A CD2 1 
ATOM   2186  C CE1 . HIS A 1 295 ? -17.153 -3.170  -8.566   1.00 31.54  ? 288  HIS A CE1 1 
ATOM   2187  N NE2 . HIS A 1 295 ? -16.280 -2.714  -9.485   1.00 31.03  ? 288  HIS A NE2 1 
ATOM   2188  N N   . GLU A 1 296 ? -18.650 -7.833  -13.087  1.00 29.39  ? 289  GLU A N   1 
ATOM   2189  C CA  . GLU A 1 296 ? -19.496 -8.662  -13.992  1.00 32.47  ? 289  GLU A CA  1 
ATOM   2190  C C   . GLU A 1 296 ? -18.942 -10.092 -14.118  1.00 30.01  ? 289  GLU A C   1 
ATOM   2191  O O   . GLU A 1 296 ? -19.522 -10.888 -14.883  1.00 26.66  ? 289  GLU A O   1 
ATOM   2192  C CB  . GLU A 1 296 ? -19.609 -8.002  -15.367  1.00 36.65  ? 289  GLU A CB  1 
ATOM   2193  C CG  . GLU A 1 296 ? -20.604 -6.854  -15.415  1.00 41.48  ? 289  GLU A CG  1 
ATOM   2194  C CD  . GLU A 1 296 ? -20.888 -6.322  -16.824  1.00 48.90  ? 289  GLU A CD  1 
ATOM   2195  O OE1 . GLU A 1 296 ? -20.686 -7.072  -17.823  1.00 46.06  ? 289  GLU A OE1 1 
ATOM   2196  O OE2 . GLU A 1 296 ? -21.329 -5.148  -16.920  1.00 58.27  ? 289  GLU A OE2 1 
ATOM   2197  N N   A ASN A 1 297 ? -17.868 -10.422 -13.391  0.50 27.83  ? 290  ASN A N   1 
ATOM   2198  N N   B ASN A 1 297 ? -17.864 -10.416 -13.396  0.50 28.41  ? 290  ASN A N   1 
ATOM   2199  C CA  A ASN A 1 297 ? -17.152 -11.722 -13.521  0.50 27.24  ? 290  ASN A CA  1 
ATOM   2200  C CA  B ASN A 1 297 ? -17.152 -11.716 -13.520  0.50 28.16  ? 290  ASN A CA  1 
ATOM   2201  C C   A ASN A 1 297 ? -16.794 -11.947 -14.994  0.50 27.66  ? 290  ASN A C   1 
ATOM   2202  C C   B ASN A 1 297 ? -16.795 -11.947 -14.994  0.50 28.18  ? 290  ASN A C   1 
ATOM   2203  O O   A ASN A 1 297 ? -17.093 -13.045 -15.514  0.50 27.96  ? 290  ASN A O   1 
ATOM   2204  O O   B ASN A 1 297 ? -17.093 -13.045 -15.511  0.50 28.45  ? 290  ASN A O   1 
ATOM   2205  C CB  A ASN A 1 297 ? -17.957 -12.910 -12.981  0.50 26.63  ? 290  ASN A CB  1 
ATOM   2206  C CB  B ASN A 1 297 ? -17.964 -12.864 -12.919  0.50 28.18  ? 290  ASN A CB  1 
ATOM   2207  C CG  A ASN A 1 297 ? -17.110 -14.151 -12.755  0.50 26.22  ? 290  ASN A CG  1 
ATOM   2208  C CG  B ASN A 1 297 ? -18.065 -12.768 -11.409  0.50 28.88  ? 290  ASN A CG  1 
ATOM   2209  O OD1 A ASN A 1 297 ? -15.887 -14.085 -12.659  0.50 26.24  ? 290  ASN A OD1 1 
ATOM   2210  O OD1 B ASN A 1 297 ? -17.048 -12.737 -10.709  0.50 28.40  ? 290  ASN A OD1 1 
ATOM   2211  N ND2 A ASN A 1 297 ? -17.749 -15.304 -12.667  0.50 26.21  ? 290  ASN A ND2 1 
ATOM   2212  N ND2 B ASN A 1 297 ? -19.285 -12.700 -10.898  0.50 28.04  ? 290  ASN A ND2 1 
ATOM   2213  N N   . VAL A 1 298 ? -16.182 -10.935 -15.624  1.00 28.22  ? 291  VAL A N   1 
ATOM   2214  C CA  . VAL A 1 298 ? -15.688 -10.975 -17.031  1.00 28.30  ? 291  VAL A CA  1 
ATOM   2215  C C   . VAL A 1 298 ? -14.211 -11.379 -17.026  1.00 26.40  ? 291  VAL A C   1 
ATOM   2216  O O   . VAL A 1 298 ? -13.422 -10.726 -16.316  1.00 24.47  ? 291  VAL A O   1 
ATOM   2217  C CB  . VAL A 1 298 ? -15.905 -9.621  -17.731  1.00 28.55  ? 291  VAL A CB  1 
ATOM   2218  C CG1 . VAL A 1 298 ? -15.057 -9.444  -18.979  1.00 30.58  ? 291  VAL A CG1 1 
ATOM   2219  C CG2 . VAL A 1 298 ? -17.358 -9.469  -18.077  1.00 29.04  ? 291  VAL A CG2 1 
ATOM   2220  N N   . GLN A 1 299 ? -13.885 -12.426 -17.783  1.00 26.72  ? 292  GLN A N   1 
ATOM   2221  C CA  . GLN A 1 299 ? -12.500 -12.884 -17.992  1.00 28.89  ? 292  GLN A CA  1 
ATOM   2222  C C   . GLN A 1 299 ? -12.035 -12.437 -19.380  1.00 25.69  ? 292  GLN A C   1 
ATOM   2223  O O   . GLN A 1 299 ? -12.424 -13.033 -20.386  1.00 24.77  ? 292  GLN A O   1 
ATOM   2224  C CB  . GLN A 1 299 ? -12.407 -14.400 -17.789  1.00 33.98  ? 292  GLN A CB  1 
ATOM   2225  C CG  . GLN A 1 299 ? -10.960 -14.859 -17.580  1.00 39.47  ? 292  GLN A CG  1 
ATOM   2226  C CD  . GLN A 1 299 ? -10.594 -16.057 -18.424  1.00 44.13  ? 292  GLN A CD  1 
ATOM   2227  O OE1 . GLN A 1 299 ? -10.952 -17.188 -18.097  1.00 50.98  ? 292  GLN A OE1 1 
ATOM   2228  N NE2 . GLN A 1 299 ? -9.879  -15.821 -19.519  1.00 45.37  ? 292  GLN A NE2 1 
ATOM   2229  N N   . PRO A 1 300 ? -11.164 -11.403 -19.489  1.00 22.12  ? 293  PRO A N   1 
ATOM   2230  C CA  . PRO A 1 300 ? -10.544 -11.061 -20.757  1.00 20.39  ? 293  PRO A CA  1 
ATOM   2231  C C   . PRO A 1 300 ? -9.459  -12.093 -21.080  1.00 19.31  ? 293  PRO A C   1 
ATOM   2232  O O   . PRO A 1 300 ? -9.122  -12.882 -20.231  1.00 18.22  ? 293  PRO A O   1 
ATOM   2233  C CB  . PRO A 1 300 ? -9.965  -9.671  -20.492  1.00 19.98  ? 293  PRO A CB  1 
ATOM   2234  C CG  . PRO A 1 300 ? -9.548  -9.751  -19.060  1.00 21.07  ? 293  PRO A CG  1 
ATOM   2235  C CD  . PRO A 1 300 ? -10.643 -10.565 -18.398  1.00 22.11  ? 293  PRO A CD  1 
ATOM   2236  N N   . ASP A 1 301 ? -8.978  -12.080 -22.318  1.00 19.89  ? 294  ASP A N   1 
ATOM   2237  C CA  . ASP A 1 301 ? -7.852  -12.933 -22.777  1.00 21.30  ? 294  ASP A CA  1 
ATOM   2238  C C   . ASP A 1 301 ? -6.559  -12.373 -22.194  1.00 18.54  ? 294  ASP A C   1 
ATOM   2239  O O   . ASP A 1 301 ? -5.683  -13.174 -21.842  1.00 15.41  ? 294  ASP A O   1 
ATOM   2240  C CB  . ASP A 1 301 ? -7.810  -12.988 -24.307  1.00 21.87  ? 294  ASP A CB  1 
ATOM   2241  C CG  . ASP A 1 301 ? -9.024  -13.703 -24.842  1.00 23.48  ? 294  ASP A CG  1 
ATOM   2242  O OD1 . ASP A 1 301 ? -9.124  -14.893 -24.566  1.00 26.31  ? 294  ASP A OD1 1 
ATOM   2243  O OD2 . ASP A 1 301 ? -9.874  -13.056 -25.494  1.00 25.58  ? 294  ASP A OD2 1 
ATOM   2244  N N   . ILE A 1 302 ? -6.491  -11.042 -22.128  1.00 18.88  ? 295  ILE A N   1 
ATOM   2245  C CA  . ILE A 1 302 ? -5.281  -10.270 -21.730  1.00 19.91  ? 295  ILE A CA  1 
ATOM   2246  C C   . ILE A 1 302 ? -5.732  -9.116  -20.843  1.00 20.60  ? 295  ILE A C   1 
ATOM   2247  O O   . ILE A 1 302 ? -6.697  -8.407  -21.235  1.00 19.43  ? 295  ILE A O   1 
ATOM   2248  C CB  . ILE A 1 302 ? -4.511  -9.733  -22.946  1.00 20.28  ? 295  ILE A CB  1 
ATOM   2249  C CG1 . ILE A 1 302 ? -4.195  -10.827 -23.969  1.00 20.66  ? 295  ILE A CG1 1 
ATOM   2250  C CG2 . ILE A 1 302 ? -3.262  -9.027  -22.484  1.00 20.78  ? 295  ILE A CG2 1 
ATOM   2251  C CD1 . ILE A 1 302 ? -3.740  -10.312 -25.326  1.00 20.09  ? 295  ILE A CD1 1 
ATOM   2252  N N   . LEU A 1 303 ? -5.056  -8.975  -19.698  1.00 20.75  ? 296  LEU A N   1 
ATOM   2253  C CA  . LEU A 1 303 ? -5.301  -7.929  -18.684  1.00 19.12  ? 296  LEU A CA  1 
ATOM   2254  C C   . LEU A 1 303 ? -4.040  -7.068  -18.529  1.00 18.98  ? 296  LEU A C   1 
ATOM   2255  O O   . LEU A 1 303 ? -2.931  -7.633  -18.363  1.00 18.32  ? 296  LEU A O   1 
ATOM   2256  C CB  . LEU A 1 303 ? -5.691  -8.620  -17.381  1.00 19.23  ? 296  LEU A CB  1 
ATOM   2257  C CG  . LEU A 1 303 ? -5.900  -7.685  -16.191  1.00 19.46  ? 296  LEU A CG  1 
ATOM   2258  C CD1 . LEU A 1 303 ? -7.068  -6.747  -16.466  1.00 19.46  ? 296  LEU A CD1 1 
ATOM   2259  C CD2 . LEU A 1 303 ? -6.086  -8.481  -14.911  1.00 19.15  ? 296  LEU A CD2 1 
ATOM   2260  N N   . CYS A 1 304 ? -4.219  -5.747  -18.554  1.00 18.25  ? 297  CYS A N   1 
ATOM   2261  C CA  . CYS A 1 304 ? -3.138  -4.754  -18.387  1.00 17.62  ? 297  CYS A CA  1 
ATOM   2262  C C   . CYS A 1 304 ? -3.264  -4.053  -17.034  1.00 17.41  ? 297  CYS A C   1 
ATOM   2263  O O   . CYS A 1 304 ? -4.369  -3.585  -16.696  1.00 16.93  ? 297  CYS A O   1 
ATOM   2264  C CB  . CYS A 1 304 ? -3.185  -3.732  -19.508  1.00 18.38  ? 297  CYS A CB  1 
ATOM   2265  S SG  . CYS A 1 304 ? -3.023  -4.478  -21.149  1.00 18.52  ? 297  CYS A SG  1 
ATOM   2266  N N   . LEU A 1 305 ? -2.151  -3.977  -16.313  1.00 17.35  ? 298  LEU A N   1 
ATOM   2267  C CA  . LEU A 1 305 ? -2.051  -3.344  -14.982  1.00 17.52  ? 298  LEU A CA  1 
ATOM   2268  C C   . LEU A 1 305 ? -0.799  -2.469  -14.933  1.00 18.73  ? 298  LEU A C   1 
ATOM   2269  O O   . LEU A 1 305 ? 0.236   -2.853  -15.525  1.00 17.24  ? 298  LEU A O   1 
ATOM   2270  C CB  . LEU A 1 305 ? -1.914  -4.436  -13.927  1.00 17.40  ? 298  LEU A CB  1 
ATOM   2271  C CG  . LEU A 1 305 ? -3.040  -5.450  -13.828  1.00 17.20  ? 298  LEU A CG  1 
ATOM   2272  C CD1 . LEU A 1 305 ? -2.701  -6.457  -12.725  1.00 17.15  ? 298  LEU A CD1 1 
ATOM   2273  C CD2 . LEU A 1 305 ? -4.369  -4.756  -13.557  1.00 17.25  ? 298  LEU A CD2 1 
ATOM   2274  N N   . ALA A 1 306 ? -0.902  -1.359  -14.204  1.00 19.86  ? 299  ALA A N   1 
ATOM   2275  C CA  . ALA A 1 306 ? 0.225   -0.501  -13.783  1.00 20.44  ? 299  ALA A CA  1 
ATOM   2276  C C   . ALA A 1 306 ? -0.269  0.393   -12.640  1.00 20.22  ? 299  ALA A C   1 
ATOM   2277  O O   . ALA A 1 306 ? -1.047  -0.097  -11.853  1.00 21.25  ? 299  ALA A O   1 
ATOM   2278  C CB  . ALA A 1 306 ? 0.749   0.273   -14.980  1.00 20.44  ? 299  ALA A CB  1 
ATOM   2279  N N   . LYS A 1 307 ? 0.148   1.659   -12.600  1.00 21.95  ? 300  LYS A N   1 
ATOM   2280  C CA  . LYS A 1 307 ? -0.147  2.669   -11.549  1.00 23.01  ? 300  LYS A CA  1 
ATOM   2281  C C   . LYS A 1 307 ? -0.053  2.024   -10.157  1.00 24.39  ? 300  LYS A C   1 
ATOM   2282  O O   . LYS A 1 307 ? 1.070   1.808   -9.687   1.00 26.18  ? 300  LYS A O   1 
ATOM   2283  C CB  . LYS A 1 307 ? -1.488  3.334   -11.853  1.00 24.51  ? 300  LYS A CB  1 
ATOM   2284  C CG  . LYS A 1 307 ? -1.537  3.974   -13.227  1.00 27.16  ? 300  LYS A CG  1 
ATOM   2285  C CD  . LYS A 1 307 ? -2.624  4.997   -13.442  1.00 28.34  ? 300  LYS A CD  1 
ATOM   2286  C CE  . LYS A 1 307 ? -2.066  6.173   -14.208  1.00 30.23  ? 300  LYS A CE  1 
ATOM   2287  N NZ  . LYS A 1 307 ? -3.116  7.067   -14.731  1.00 33.36  ? 300  LYS A NZ  1 
ATOM   2288  N N   . ALA A 1 308 ? -1.187  1.700   -9.531   1.00 24.06  ? 301  ALA A N   1 
ATOM   2289  C CA  . ALA A 1 308 ? -1.264  1.299   -8.112   1.00 22.14  ? 301  ALA A CA  1 
ATOM   2290  C C   . ALA A 1 308 ? -0.520  -0.020  -7.882   1.00 20.32  ? 301  ALA A C   1 
ATOM   2291  O O   . ALA A 1 308 ? -0.152  -0.255  -6.737   1.00 19.53  ? 301  ALA A O   1 
ATOM   2292  C CB  . ALA A 1 308 ? -2.709  1.220   -7.680   1.00 23.40  ? 301  ALA A CB  1 
ATOM   2293  N N   . LEU A 1 309 ? -0.280  -0.836  -8.907   1.00 18.75  ? 302  LEU A N   1 
ATOM   2294  C CA  . LEU A 1 309 ? 0.425   -2.131  -8.728   1.00 18.42  ? 302  LEU A CA  1 
ATOM   2295  C C   . LEU A 1 309 ? 1.804   -1.921  -8.071   1.00 18.76  ? 302  LEU A C   1 
ATOM   2296  O O   . LEU A 1 309 ? 2.280   -2.866  -7.418   1.00 19.60  ? 302  LEU A O   1 
ATOM   2297  C CB  . LEU A 1 309 ? 0.580   -2.818  -10.086  1.00 18.04  ? 302  LEU A CB  1 
ATOM   2298  C CG  . LEU A 1 309 ? 1.181   -4.221  -10.024  1.00 18.04  ? 302  LEU A CG  1 
ATOM   2299  C CD1 . LEU A 1 309 ? 0.356   -5.140  -9.130   1.00 18.14  ? 302  LEU A CD1 1 
ATOM   2300  C CD2 . LEU A 1 309 ? 1.289   -4.809  -11.409  1.00 17.63  ? 302  LEU A CD2 1 
ATOM   2301  N N   . GLY A 1 310 ? 2.431   -0.749  -8.220   1.00 18.00  ? 303  GLY A N   1 
ATOM   2302  C CA  . GLY A 1 310 ? 3.759   -0.460  -7.635   1.00 19.10  ? 303  GLY A CA  1 
ATOM   2303  C C   . GLY A 1 310 ? 3.686   0.102   -6.215   1.00 20.01  ? 303  GLY A C   1 
ATOM   2304  O O   . GLY A 1 310 ? 4.740   0.358   -5.613   1.00 18.92  ? 303  GLY A O   1 
ATOM   2305  N N   . GLY A 1 311 ? 2.476   0.333   -5.709   1.00 18.82  ? 304  GLY A N   1 
ATOM   2306  C CA  . GLY A 1 311 ? 2.260   0.735   -4.310   1.00 19.51  ? 304  GLY A CA  1 
ATOM   2307  C C   . GLY A 1 311 ? 2.519   2.211   -4.081   1.00 19.22  ? 304  GLY A C   1 
ATOM   2308  O O   . GLY A 1 311 ? 2.572   2.581   -2.906   1.00 21.08  ? 304  GLY A O   1 
ATOM   2309  N N   . GLY A 1 312 ? 2.668   3.023   -5.128   1.00 17.80  ? 305  GLY A N   1 
ATOM   2310  C CA  . GLY A 1 312 ? 3.026   4.448   -4.992   1.00 17.74  ? 305  GLY A CA  1 
ATOM   2311  C C   . GLY A 1 312 ? 4.472   4.602   -4.571   1.00 18.76  ? 305  GLY A C   1 
ATOM   2312  O O   . GLY A 1 312 ? 4.857   5.664   -4.034   1.00 18.87  ? 305  GLY A O   1 
ATOM   2313  N N   . VAL A 1 313 ? 5.270   3.566   -4.799   1.00 19.96  ? 306  VAL A N   1 
ATOM   2314  C CA  . VAL A 1 313 ? 6.722   3.578   -4.471   1.00 20.60  ? 306  VAL A CA  1 
ATOM   2315  C C   . VAL A 1 313 ? 7.536   3.293   -5.735   1.00 20.80  ? 306  VAL A C   1 
ATOM   2316  O O   . VAL A 1 313 ? 8.444   4.101   -6.015   1.00 20.84  ? 306  VAL A O   1 
ATOM   2317  C CB  . VAL A 1 313 ? 7.028   2.589   -3.334   1.00 21.84  ? 306  VAL A CB  1 
ATOM   2318  C CG1 . VAL A 1 313 ? 8.486   2.653   -2.903   1.00 22.94  ? 306  VAL A CG1 1 
ATOM   2319  C CG2 . VAL A 1 313 ? 6.131   2.838   -2.146   1.00 22.77  ? 306  VAL A CG2 1 
ATOM   2320  N N   . MET A 1 314 ? 7.200   2.224   -6.474   1.00 22.12  ? 307  MET A N   1 
ATOM   2321  C CA  . MET A 1 314 ? 7.929   1.782   -7.695   1.00 22.37  ? 307  MET A CA  1 
ATOM   2322  C C   . MET A 1 314 ? 7.072   1.912   -8.948   1.00 24.24  ? 307  MET A C   1 
ATOM   2323  O O   . MET A 1 314 ? 5.867   1.656   -8.921   1.00 24.54  ? 307  MET A O   1 
ATOM   2324  C CB  . MET A 1 314 ? 8.374   0.321   -7.576   1.00 23.35  ? 307  MET A CB  1 
ATOM   2325  C CG  . MET A 1 314 ? 9.609   0.134   -6.686   1.00 23.70  ? 307  MET A CG  1 
ATOM   2326  S SD  . MET A 1 314 ? 11.037  1.110   -7.254   1.00 25.13  ? 307  MET A SD  1 
ATOM   2327  C CE  . MET A 1 314 ? 11.531  0.109   -8.662   1.00 24.48  ? 307  MET A CE  1 
ATOM   2328  N N   . PRO A 1 315 ? 7.683   2.298   -10.093  1.00 24.20  ? 308  PRO A N   1 
ATOM   2329  C CA  . PRO A 1 315 ? 7.055   2.148   -11.397  1.00 25.03  ? 308  PRO A CA  1 
ATOM   2330  C C   . PRO A 1 315 ? 7.090   0.662   -11.765  1.00 26.64  ? 308  PRO A C   1 
ATOM   2331  O O   . PRO A 1 315 ? 8.142   0.056   -11.688  1.00 28.62  ? 308  PRO A O   1 
ATOM   2332  C CB  . PRO A 1 315 ? 7.970   2.955   -12.329  1.00 25.55  ? 308  PRO A CB  1 
ATOM   2333  C CG  . PRO A 1 315 ? 9.332   2.830   -11.696  1.00 24.40  ? 308  PRO A CG  1 
ATOM   2334  C CD  . PRO A 1 315 ? 9.033   2.885   -10.209  1.00 25.06  ? 308  PRO A CD  1 
ATOM   2335  N N   . ILE A 1 316 ? 5.935   0.114   -12.125  1.00 27.80  ? 309  ILE A N   1 
ATOM   2336  C CA  . ILE A 1 316 ? 5.804   -1.269  -12.670  1.00 27.35  ? 309  ILE A CA  1 
ATOM   2337  C C   . ILE A 1 316 ? 4.570   -1.318  -13.572  1.00 27.07  ? 309  ILE A C   1 
ATOM   2338  O O   . ILE A 1 316 ? 3.605   -0.571  -13.302  1.00 28.21  ? 309  ILE A O   1 
ATOM   2339  C CB  . ILE A 1 316 ? 5.716   -2.303  -11.530  1.00 26.45  ? 309  ILE A CB  1 
ATOM   2340  C CG1 . ILE A 1 316 ? 5.689   -3.745  -12.041  1.00 25.29  ? 309  ILE A CG1 1 
ATOM   2341  C CG2 . ILE A 1 316 ? 4.528   -2.010  -10.634  1.00 26.42  ? 309  ILE A CG2 1 
ATOM   2342  C CD1 . ILE A 1 316 ? 5.764   -4.782  -10.943  1.00 25.59  ? 309  ILE A CD1 1 
ATOM   2343  N N   . GLY A 1 317 ? 4.612   -2.178  -14.587  1.00 25.32  ? 310  GLY A N   1 
ATOM   2344  C CA  . GLY A 1 317 ? 3.427   -2.627  -15.337  1.00 24.39  ? 310  GLY A CA  1 
ATOM   2345  C C   . GLY A 1 317 ? 3.385   -4.139  -15.383  1.00 23.33  ? 310  GLY A C   1 
ATOM   2346  O O   . GLY A 1 317 ? 4.452   -4.776  -15.227  1.00 23.61  ? 310  GLY A O   1 
ATOM   2347  N N   . ALA A 1 318 ? 2.206   -4.713  -15.574  1.00 21.80  ? 311  ALA A N   1 
ATOM   2348  C CA  . ALA A 1 318 ? 2.048   -6.166  -15.772  1.00 21.98  ? 311  ALA A CA  1 
ATOM   2349  C C   . ALA A 1 318 ? 1.034   -6.418  -16.881  1.00 21.53  ? 311  ALA A C   1 
ATOM   2350  O O   . ALA A 1 318 ? -0.021  -5.740  -16.905  1.00 23.28  ? 311  ALA A O   1 
ATOM   2351  C CB  . ALA A 1 318 ? 1.605   -6.814  -14.490  1.00 23.55  ? 311  ALA A CB  1 
ATOM   2352  N N   . THR A 1 319 ? 1.351   -7.368  -17.746  1.00 19.04  ? 312  THR A N   1 
ATOM   2353  C CA  . THR A 1 319 ? 0.429   -7.897  -18.760  1.00 19.14  ? 312  THR A CA  1 
ATOM   2354  C C   . THR A 1 319 ? 0.224   -9.366  -18.436  1.00 18.24  ? 312  THR A C   1 
ATOM   2355  O O   . THR A 1 319 ? 1.212   -10.101 -18.447  1.00 17.09  ? 312  THR A O   1 
ATOM   2356  C CB  . THR A 1 319 ? 1.004   -7.652  -20.157  1.00 20.51  ? 312  THR A CB  1 
ATOM   2357  O OG1 . THR A 1 319 ? 1.362   -6.272  -20.237  1.00 19.69  ? 312  THR A OG1 1 
ATOM   2358  C CG2 . THR A 1 319 ? 0.028   -8.012  -21.254  1.00 21.61  ? 312  THR A CG2 1 
ATOM   2359  N N   . ILE A 1 320 ? -1.001  -9.752  -18.112  1.00 19.11  ? 313  ILE A N   1 
ATOM   2360  C CA  . ILE A 1 320 ? -1.354  -11.152 -17.750  1.00 20.66  ? 313  ILE A CA  1 
ATOM   2361  C C   . ILE A 1 320 ? -2.306  -11.669 -18.808  1.00 19.57  ? 313  ILE A C   1 
ATOM   2362  O O   . ILE A 1 320 ? -3.138  -10.888 -19.260  1.00 21.02  ? 313  ILE A O   1 
ATOM   2363  C CB  . ILE A 1 320 ? -1.983  -11.241 -16.346  1.00 22.58  ? 313  ILE A CB  1 
ATOM   2364  C CG1 . ILE A 1 320 ? -1.199  -10.402 -15.338  1.00 24.64  ? 313  ILE A CG1 1 
ATOM   2365  C CG2 . ILE A 1 320 ? -2.121  -12.689 -15.884  1.00 22.12  ? 313  ILE A CG2 1 
ATOM   2366  C CD1 . ILE A 1 320 ? -2.046  -9.371  -14.622  1.00 26.78  ? 313  ILE A CD1 1 
ATOM   2367  N N   . ALA A 1 321 ? -2.178  -12.940 -19.167  1.00 20.37  ? 314  ALA A N   1 
ATOM   2368  C CA  . ALA A 1 321 ? -2.909  -13.558 -20.296  1.00 21.30  ? 314  ALA A CA  1 
ATOM   2369  C C   . ALA A 1 321 ? -3.066  -15.052 -20.049  1.00 22.49  ? 314  ALA A C   1 
ATOM   2370  O O   . ALA A 1 321 ? -2.345  -15.595 -19.193  1.00 22.83  ? 314  ALA A O   1 
ATOM   2371  C CB  . ALA A 1 321 ? -2.167  -13.313 -21.582  1.00 21.18  ? 314  ALA A CB  1 
ATOM   2372  N N   . THR A 1 322 ? -3.970  -15.674 -20.795  1.00 24.76  ? 315  THR A N   1 
ATOM   2373  C CA  . THR A 1 322 ? -4.194  -17.141 -20.835  1.00 25.82  ? 315  THR A CA  1 
ATOM   2374  C C   . THR A 1 322 ? -2.918  -17.835 -21.317  1.00 24.69  ? 315  THR A C   1 
ATOM   2375  O O   . THR A 1 322 ? -2.131  -17.192 -22.025  1.00 23.12  ? 315  THR A O   1 
ATOM   2376  C CB  . THR A 1 322 ? -5.373  -17.477 -21.761  1.00 26.53  ? 315  THR A CB  1 
ATOM   2377  O OG1 . THR A 1 322 ? -5.083  -16.891 -23.032  1.00 26.36  ? 315  THR A OG1 1 
ATOM   2378  C CG2 . THR A 1 322 ? -6.702  -16.971 -21.242  1.00 26.83  ? 315  THR A CG2 1 
ATOM   2379  N N   . GLU A 1 323 ? -2.752  -19.105 -20.959  1.00 25.57  ? 316  GLU A N   1 
ATOM   2380  C CA  . GLU A 1 323 ? -1.667  -19.961 -21.487  1.00 29.13  ? 316  GLU A CA  1 
ATOM   2381  C C   . GLU A 1 323 ? -1.815  -20.033 -23.011  1.00 28.90  ? 316  GLU A C   1 
ATOM   2382  O O   . GLU A 1 323 ? -0.787  -20.009 -23.696  1.00 26.60  ? 316  GLU A O   1 
ATOM   2383  C CB  . GLU A 1 323 ? -1.720  -21.340 -20.833  1.00 33.08  ? 316  GLU A CB  1 
ATOM   2384  C CG  . GLU A 1 323 ? -0.659  -22.303 -21.343  1.00 37.38  ? 316  GLU A CG  1 
ATOM   2385  C CD  . GLU A 1 323 ? -0.190  -23.333 -20.314  1.00 42.09  ? 316  GLU A CD  1 
ATOM   2386  O OE1 . GLU A 1 323 ? -0.639  -23.277 -19.150  1.00 42.21  ? 316  GLU A OE1 1 
ATOM   2387  O OE2 . GLU A 1 323 ? 0.655   -24.185 -20.670  1.00 54.70  ? 316  GLU A OE2 1 
ATOM   2388  N N   . GLU A 1 324 ? -3.057  -20.089 -23.502  1.00 30.38  ? 317  GLU A N   1 
ATOM   2389  C CA  . GLU A 1 324 ? -3.415  -20.217 -24.947  1.00 29.42  ? 317  GLU A CA  1 
ATOM   2390  C C   . GLU A 1 324 ? -2.744  -19.080 -25.731  1.00 25.69  ? 317  GLU A C   1 
ATOM   2391  O O   . GLU A 1 324 ? -2.076  -19.377 -26.725  1.00 22.69  ? 317  GLU A O   1 
ATOM   2392  C CB  . GLU A 1 324 ? -4.947  -20.236 -25.118  1.00 34.24  ? 317  GLU A CB  1 
ATOM   2393  C CG  . GLU A 1 324 ? -5.442  -20.421 -26.555  1.00 35.84  ? 317  GLU A CG  1 
ATOM   2394  C CD  . GLU A 1 324 ? -4.882  -21.606 -27.333  1.00 38.30  ? 317  GLU A CD  1 
ATOM   2395  O OE1 . GLU A 1 324 ? -4.563  -22.618 -26.697  1.00 42.34  ? 317  GLU A OE1 1 
ATOM   2396  O OE2 . GLU A 1 324 ? -4.763  -21.514 -28.584  1.00 40.31  ? 317  GLU A OE2 1 
ATOM   2397  N N   . VAL A 1 325 ? -2.864  -17.842 -25.246  1.00 23.72  ? 318  VAL A N   1 
ATOM   2398  C CA  . VAL A 1 325 ? -2.342  -16.605 -25.904  1.00 21.30  ? 318  VAL A CA  1 
ATOM   2399  C C   . VAL A 1 325 ? -0.847  -16.429 -25.588  1.00 21.77  ? 318  VAL A C   1 
ATOM   2400  O O   . VAL A 1 325 ? -0.078  -16.144 -26.505  1.00 20.62  ? 318  VAL A O   1 
ATOM   2401  C CB  . VAL A 1 325 ? -3.134  -15.377 -25.421  1.00 20.15  ? 318  VAL A CB  1 
ATOM   2402  C CG1 . VAL A 1 325 ? -2.468  -14.063 -25.807  1.00 18.78  ? 318  VAL A CG1 1 
ATOM   2403  C CG2 . VAL A 1 325 ? -4.578  -15.437 -25.895  1.00 19.72  ? 318  VAL A CG2 1 
ATOM   2404  N N   . PHE A 1 326 ? -0.449  -16.530 -24.323  1.00 20.52  ? 319  PHE A N   1 
ATOM   2405  C CA  . PHE A 1 326 ? 0.921   -16.189 -23.876  1.00 20.70  ? 319  PHE A CA  1 
ATOM   2406  C C   . PHE A 1 326 ? 1.903   -17.199 -24.467  1.00 20.99  ? 319  PHE A C   1 
ATOM   2407  O O   . PHE A 1 326 ? 3.046   -16.804 -24.720  1.00 20.46  ? 319  PHE A O   1 
ATOM   2408  C CB  . PHE A 1 326 ? 0.982   -16.153 -22.347  1.00 21.21  ? 319  PHE A CB  1 
ATOM   2409  C CG  . PHE A 1 326 ? 2.032   -15.242 -21.764  1.00 20.61  ? 319  PHE A CG  1 
ATOM   2410  C CD1 . PHE A 1 326 ? 3.345   -15.667 -21.635  1.00 19.19  ? 319  PHE A CD1 1 
ATOM   2411  C CD2 . PHE A 1 326 ? 1.690   -13.976 -21.301  1.00 20.77  ? 319  PHE A CD2 1 
ATOM   2412  C CE1 . PHE A 1 326 ? 4.299   -14.840 -21.071  1.00 18.77  ? 319  PHE A CE1 1 
ATOM   2413  C CE2 . PHE A 1 326 ? 2.653   -13.146 -20.749  1.00 20.98  ? 319  PHE A CE2 1 
ATOM   2414  C CZ  . PHE A 1 326 ? 3.956   -13.584 -20.636  1.00 19.51  ? 319  PHE A CZ  1 
ATOM   2415  N N   . SER A 1 327 ? 1.462   -18.436 -24.729  1.00 22.35  ? 320  SER A N   1 
ATOM   2416  C CA  . SER A 1 327 ? 2.316   -19.550 -25.233  1.00 23.85  ? 320  SER A CA  1 
ATOM   2417  C C   . SER A 1 327 ? 3.016   -19.154 -26.541  1.00 24.11  ? 320  SER A C   1 
ATOM   2418  O O   . SER A 1 327 ? 3.933   -19.901 -26.976  1.00 24.49  ? 320  SER A O   1 
ATOM   2419  C CB  . SER A 1 327 ? 1.546   -20.839 -25.405  1.00 24.48  ? 320  SER A CB  1 
ATOM   2420  O OG  . SER A 1 327 ? 0.532   -20.697 -26.380  1.00 24.46  ? 320  SER A OG  1 
ATOM   2421  N N   . VAL A 1 328 ? 2.635   -18.020 -27.135  1.00 23.48  ? 321  VAL A N   1 
ATOM   2422  C CA  . VAL A 1 328 ? 3.306   -17.456 -28.344  1.00 23.58  ? 321  VAL A CA  1 
ATOM   2423  C C   . VAL A 1 328 ? 4.749   -17.079 -28.002  1.00 24.82  ? 321  VAL A C   1 
ATOM   2424  O O   . VAL A 1 328 ? 5.542   -16.982 -28.973  1.00 26.92  ? 321  VAL A O   1 
ATOM   2425  C CB  . VAL A 1 328 ? 2.548   -16.261 -28.960  1.00 22.29  ? 321  VAL A CB  1 
ATOM   2426  C CG1 . VAL A 1 328 ? 1.189   -16.685 -29.476  1.00 21.69  ? 321  VAL A CG1 1 
ATOM   2427  C CG2 . VAL A 1 328 ? 2.437   -15.074 -28.019  1.00 21.75  ? 321  VAL A CG2 1 
ATOM   2428  N N   . LEU A 1 329 ? 5.078   -16.891 -26.710  1.00 23.81  ? 322  LEU A N   1 
ATOM   2429  C CA  . LEU A 1 329 ? 6.413   -16.434 -26.245  1.00 23.36  ? 322  LEU A CA  1 
ATOM   2430  C C   . LEU A 1 329 ? 7.265   -17.610 -25.765  1.00 23.71  ? 322  LEU A C   1 
ATOM   2431  O O   . LEU A 1 329 ? 8.405   -17.354 -25.416  1.00 23.26  ? 322  LEU A O   1 
ATOM   2432  C CB  . LEU A 1 329 ? 6.241   -15.412 -25.121  1.00 24.13  ? 322  LEU A CB  1 
ATOM   2433  C CG  . LEU A 1 329 ? 5.434   -14.151 -25.439  1.00 25.01  ? 322  LEU A CG  1 
ATOM   2434  C CD1 . LEU A 1 329 ? 5.543   -13.142 -24.296  1.00 24.40  ? 322  LEU A CD1 1 
ATOM   2435  C CD2 . LEU A 1 329 ? 5.867   -13.489 -26.737  1.00 26.12  ? 322  LEU A CD2 1 
ATOM   2436  N N   . PHE A 1 330 ? 6.764   -18.844 -25.806  1.00 25.58  ? 323  PHE A N   1 
ATOM   2437  C CA  . PHE A 1 330 ? 7.410   -20.042 -25.197  1.00 28.80  ? 323  PHE A CA  1 
ATOM   2438  C C   . PHE A 1 330 ? 8.562   -20.588 -26.051  1.00 31.48  ? 323  PHE A C   1 
ATOM   2439  O O   . PHE A 1 330 ? 9.536   -21.049 -25.431  1.00 29.88  ? 323  PHE A O   1 
ATOM   2440  C CB  . PHE A 1 330 ? 6.381   -21.146 -24.953  1.00 29.90  ? 323  PHE A CB  1 
ATOM   2441  C CG  . PHE A 1 330 ? 5.397   -20.877 -23.839  1.00 30.50  ? 323  PHE A CG  1 
ATOM   2442  C CD1 . PHE A 1 330 ? 5.385   -19.674 -23.146  1.00 30.40  ? 323  PHE A CD1 1 
ATOM   2443  C CD2 . PHE A 1 330 ? 4.440   -21.826 -23.519  1.00 32.37  ? 323  PHE A CD2 1 
ATOM   2444  C CE1 . PHE A 1 330 ? 4.464   -19.445 -22.132  1.00 31.77  ? 323  PHE A CE1 1 
ATOM   2445  C CE2 . PHE A 1 330 ? 3.508   -21.591 -22.516  1.00 34.30  ? 323  PHE A CE2 1 
ATOM   2446  C CZ  . PHE A 1 330 ? 3.527   -20.404 -21.815  1.00 33.68  ? 323  PHE A CZ  1 
ATOM   2447  N N   . ASP A 1 331 ? 8.456   -20.586 -27.386  1.00 37.14  ? 324  ASP A N   1 
ATOM   2448  C CA  . ASP A 1 331 ? 9.487   -21.173 -28.291  1.00 43.10  ? 324  ASP A CA  1 
ATOM   2449  C C   . ASP A 1 331 ? 10.699  -20.248 -28.346  1.00 39.70  ? 324  ASP A C   1 
ATOM   2450  O O   . ASP A 1 331 ? 11.819  -20.764 -28.429  1.00 38.40  ? 324  ASP A O   1 
ATOM   2451  C CB  . ASP A 1 331 ? 8.999   -21.406 -29.725  1.00 51.48  ? 324  ASP A CB  1 
ATOM   2452  C CG  . ASP A 1 331 ? 8.138   -22.644 -29.881  1.00 65.31  ? 324  ASP A CG  1 
ATOM   2453  O OD1 . ASP A 1 331 ? 7.852   -23.286 -28.849  1.00 80.76  ? 324  ASP A OD1 1 
ATOM   2454  O OD2 . ASP A 1 331 ? 7.754   -22.955 -31.030  1.00 81.21  ? 324  ASP A OD2 1 
ATOM   2455  N N   . ASN A 1 332 ? 10.454  -18.938 -28.378  1.00 37.24  ? 325  ASN A N   1 
ATOM   2456  C CA  . ASN A 1 332 ? 11.493  -17.884 -28.330  1.00 35.49  ? 325  ASN A CA  1 
ATOM   2457  C C   . ASN A 1 332 ? 11.115  -16.897 -27.238  1.00 34.00  ? 325  ASN A C   1 
ATOM   2458  O O   . ASN A 1 332 ? 10.387  -15.933 -27.464  1.00 32.24  ? 325  ASN A O   1 
ATOM   2459  C CB  . ASN A 1 332 ? 11.688  -17.163 -29.660  1.00 37.02  ? 325  ASN A CB  1 
ATOM   2460  C CG  . ASN A 1 332 ? 12.849  -16.198 -29.607  1.00 39.77  ? 325  ASN A CG  1 
ATOM   2461  O OD1 . ASN A 1 332 ? 13.597  -16.174 -28.622  1.00 40.43  ? 325  ASN A OD1 1 
ATOM   2462  N ND2 . ASN A 1 332 ? 12.995  -15.406 -30.661  1.00 41.45  ? 325  ASN A ND2 1 
ATOM   2463  N N   . PRO A 1 333 ? 11.637  -17.102 -26.013  1.00 34.52  ? 326  PRO A N   1 
ATOM   2464  C CA  . PRO A 1 333 ? 11.316  -16.224 -24.888  1.00 32.24  ? 326  PRO A CA  1 
ATOM   2465  C C   . PRO A 1 333 ? 11.927  -14.816 -24.992  1.00 30.52  ? 326  PRO A C   1 
ATOM   2466  O O   . PRO A 1 333 ? 11.673  -14.010 -24.123  1.00 30.32  ? 326  PRO A O   1 
ATOM   2467  C CB  . PRO A 1 333 ? 11.862  -17.005 -23.691  1.00 32.47  ? 326  PRO A CB  1 
ATOM   2468  C CG  . PRO A 1 333 ? 12.985  -17.818 -24.264  1.00 33.67  ? 326  PRO A CG  1 
ATOM   2469  C CD  . PRO A 1 333 ? 12.534  -18.207 -25.648  1.00 33.65  ? 326  PRO A CD  1 
ATOM   2470  N N   . PHE A 1 334 ? 12.694  -14.533 -26.046  1.00 28.48  ? 327  PHE A N   1 
ATOM   2471  C CA  . PHE A 1 334 ? 13.285  -13.193 -26.275  1.00 29.64  ? 327  PHE A CA  1 
ATOM   2472  C C   . PHE A 1 334 ? 12.444  -12.429 -27.289  1.00 29.79  ? 327  PHE A C   1 
ATOM   2473  O O   . PHE A 1 334 ? 12.814  -11.312 -27.647  1.00 33.55  ? 327  PHE A O   1 
ATOM   2474  C CB  . PHE A 1 334 ? 14.749  -13.319 -26.694  1.00 32.12  ? 327  PHE A CB  1 
ATOM   2475  C CG  . PHE A 1 334 ? 15.544  -14.055 -25.654  1.00 34.07  ? 327  PHE A CG  1 
ATOM   2476  C CD1 . PHE A 1 334 ? 15.788  -13.468 -24.423  1.00 37.47  ? 327  PHE A CD1 1 
ATOM   2477  C CD2 . PHE A 1 334 ? 15.938  -15.368 -25.856  1.00 36.58  ? 327  PHE A CD2 1 
ATOM   2478  C CE1 . PHE A 1 334 ? 16.476  -14.156 -23.434  1.00 40.19  ? 327  PHE A CE1 1 
ATOM   2479  C CE2 . PHE A 1 334 ? 16.623  -16.057 -24.867  1.00 40.79  ? 327  PHE A CE2 1 
ATOM   2480  C CZ  . PHE A 1 334 ? 16.897  -15.447 -23.660  1.00 40.30  ? 327  PHE A CZ  1 
ATOM   2481  N N   . LEU A 1 335 ? 11.334  -13.005 -27.733  1.00 27.05  ? 328  LEU A N   1 
ATOM   2482  C CA  . LEU A 1 335 ? 10.472  -12.372 -28.748  1.00 25.83  ? 328  LEU A CA  1 
ATOM   2483  C C   . LEU A 1 335 ? 10.009  -11.004 -28.227  1.00 24.69  ? 328  LEU A C   1 
ATOM   2484  O O   . LEU A 1 335 ? 9.960   -10.038 -29.008  1.00 22.89  ? 328  LEU A O   1 
ATOM   2485  C CB  . LEU A 1 335 ? 9.298   -13.324 -28.992  1.00 27.45  ? 328  LEU A CB  1 
ATOM   2486  C CG  . LEU A 1 335 ? 8.582   -13.152 -30.321  1.00 27.96  ? 328  LEU A CG  1 
ATOM   2487  C CD1 . LEU A 1 335 ? 9.583   -13.058 -31.451  1.00 29.11  ? 328  LEU A CD1 1 
ATOM   2488  C CD2 . LEU A 1 335 ? 7.607   -14.287 -30.569  1.00 27.93  ? 328  LEU A CD2 1 
ATOM   2489  N N   . HIS A 1 336 ? 9.634   -10.950 -26.948  1.00 24.11  ? 329  HIS A N   1 
ATOM   2490  C CA  . HIS A 1 336 ? 9.297   -9.700  -26.218  1.00 23.92  ? 329  HIS A CA  1 
ATOM   2491  C C   . HIS A 1 336 ? 10.068  -9.704  -24.900  1.00 26.42  ? 329  HIS A C   1 
ATOM   2492  O O   . HIS A 1 336 ? 9.954   -10.685 -24.129  1.00 27.32  ? 329  HIS A O   1 
ATOM   2493  C CB  . HIS A 1 336 ? 7.782   -9.514  -25.990  1.00 21.64  ? 329  HIS A CB  1 
ATOM   2494  C CG  . HIS A 1 336 ? 7.430   -8.134  -25.534  1.00 20.42  ? 329  HIS A CG  1 
ATOM   2495  N ND1 . HIS A 1 336 ? 7.747   -7.005  -26.266  1.00 19.22  ? 329  HIS A ND1 1 
ATOM   2496  C CD2 . HIS A 1 336 ? 6.816   -7.684  -24.415  1.00 20.95  ? 329  HIS A CD2 1 
ATOM   2497  C CE1 . HIS A 1 336 ? 7.333   -5.923  -25.632  1.00 19.35  ? 329  HIS A CE1 1 
ATOM   2498  N NE2 . HIS A 1 336 ? 6.752   -6.311  -24.491  1.00 19.91  ? 329  HIS A NE2 1 
ATOM   2499  N N   . THR A 1 337 ? 10.833  -8.636  -24.686  1.00 27.28  ? 330  THR A N   1 
ATOM   2500  C CA  . THR A 1 337 ? 11.674  -8.406  -23.496  1.00 27.30  ? 330  THR A CA  1 
ATOM   2501  C C   . THR A 1 337 ? 11.697  -6.913  -23.190  1.00 29.27  ? 330  THR A C   1 
ATOM   2502  O O   . THR A 1 337 ? 11.275  -6.102  -24.036  1.00 27.21  ? 330  THR A O   1 
ATOM   2503  C CB  . THR A 1 337 ? 13.085  -8.954  -23.706  1.00 27.32  ? 330  THR A CB  1 
ATOM   2504  O OG1 . THR A 1 337 ? 13.719  -8.280  -24.802  1.00 25.31  ? 330  THR A OG1 1 
ATOM   2505  C CG2 . THR A 1 337 ? 13.048  -10.445 -23.943  1.00 28.64  ? 330  THR A CG2 1 
ATOM   2506  N N   . THR A 1 338 ? 12.136  -6.601  -21.978  1.00 32.56  ? 331  THR A N   1 
ATOM   2507  C CA  . THR A 1 338 ? 12.525  -5.241  -21.532  1.00 34.11  ? 331  THR A CA  1 
ATOM   2508  C C   . THR A 1 338 ? 13.675  -5.483  -20.553  1.00 34.52  ? 331  THR A C   1 
ATOM   2509  O O   . THR A 1 338 ? 13.775  -6.618  -20.006  1.00 37.18  ? 331  THR A O   1 
ATOM   2510  C CB  . THR A 1 338 ? 11.298  -4.473  -21.020  1.00 33.03  ? 331  THR A CB  1 
ATOM   2511  O OG1 . THR A 1 338 ? 11.553  -3.066  -21.077  1.00 34.82  ? 331  THR A OG1 1 
ATOM   2512  C CG2 . THR A 1 338 ? 10.900  -4.881  -19.619  1.00 31.50  ? 331  THR A CG2 1 
ATOM   2513  N N   A THR A 1 339 ? 14.532  -4.484  -20.356  0.50 33.84  ? 332  THR A N   1 
ATOM   2514  N N   B THR A 1 339 ? 14.534  -4.483  -20.360  0.50 32.66  ? 332  THR A N   1 
ATOM   2515  C CA  A THR A 1 339 ? 15.748  -4.610  -19.515  0.50 32.49  ? 332  THR A CA  1 
ATOM   2516  C CA  B THR A 1 339 ? 15.759  -4.591  -19.525  0.50 30.72  ? 332  THR A CA  1 
ATOM   2517  C C   A THR A 1 339 ? 15.345  -4.552  -18.036  0.50 29.65  ? 332  THR A C   1 
ATOM   2518  C C   B THR A 1 339 ? 15.349  -4.547  -18.042  0.50 28.70  ? 332  THR A C   1 
ATOM   2519  O O   A THR A 1 339 ? 15.752  -5.457  -17.283  0.50 30.33  ? 332  THR A O   1 
ATOM   2520  O O   B THR A 1 339 ? 15.752  -5.456  -17.288  0.50 29.42  ? 332  THR A O   1 
ATOM   2521  C CB  A THR A 1 339 ? 16.789  -3.572  -19.946  0.50 34.49  ? 332  THR A CB  1 
ATOM   2522  C CB  B THR A 1 339 ? 16.773  -3.523  -19.970  0.50 31.23  ? 332  THR A CB  1 
ATOM   2523  O OG1 A THR A 1 339 ? 16.159  -2.291  -19.939  0.50 36.03  ? 332  THR A OG1 1 
ATOM   2524  O OG1 B THR A 1 339 ? 17.330  -3.898  -21.234  0.50 32.77  ? 332  THR A OG1 1 
ATOM   2525  C CG2 A THR A 1 339 ? 17.342  -3.882  -21.319  0.50 35.23  ? 332  THR A CG2 1 
ATOM   2526  C CG2 B THR A 1 339 ? 17.909  -3.298  -18.996  0.50 29.94  ? 332  THR A CG2 1 
ATOM   2527  N N   . PHE A 1 340 ? 14.538  -3.563  -17.650  1.00 26.08  ? 333  PHE A N   1 
ATOM   2528  C CA  . PHE A 1 340 ? 14.182  -3.302  -16.237  1.00 24.96  ? 333  PHE A CA  1 
ATOM   2529  C C   . PHE A 1 340 ? 12.935  -4.073  -15.770  1.00 23.46  ? 333  PHE A C   1 
ATOM   2530  O O   . PHE A 1 340 ? 12.682  -4.090  -14.564  1.00 25.39  ? 333  PHE A O   1 
ATOM   2531  C CB  . PHE A 1 340 ? 13.927  -1.809  -16.069  1.00 23.53  ? 333  PHE A CB  1 
ATOM   2532  C CG  . PHE A 1 340 ? 15.097  -0.901  -16.339  1.00 21.18  ? 333  PHE A CG  1 
ATOM   2533  C CD1 . PHE A 1 340 ? 16.328  -1.111  -15.737  1.00 20.38  ? 333  PHE A CD1 1 
ATOM   2534  C CD2 . PHE A 1 340 ? 14.944  0.199   -17.164  1.00 20.51  ? 333  PHE A CD2 1 
ATOM   2535  C CE1 . PHE A 1 340 ? 17.382  -0.242  -15.951  1.00 18.71  ? 333  PHE A CE1 1 
ATOM   2536  C CE2 . PHE A 1 340 ? 15.992  1.080   -17.363  1.00 20.99  ? 333  PHE A CE2 1 
ATOM   2537  C CZ  . PHE A 1 340 ? 17.205  0.862   -16.742  1.00 20.36  ? 333  PHE A CZ  1 
ATOM   2538  N N   . GLY A 1 341 ? 12.162  -4.674  -16.665  1.00 21.84  ? 334  GLY A N   1 
ATOM   2539  C CA  . GLY A 1 341 ? 10.824  -5.210  -16.338  1.00 20.68  ? 334  GLY A CA  1 
ATOM   2540  C C   . GLY A 1 341 ? 10.907  -6.405  -15.409  1.00 19.14  ? 334  GLY A C   1 
ATOM   2541  O O   . GLY A 1 341 ? 11.721  -7.289  -15.655  1.00 19.16  ? 334  GLY A O   1 
ATOM   2542  N N   . GLY A 1 342 ? 10.087  -6.429  -14.365  1.00 19.34  ? 335  GLY A N   1 
ATOM   2543  C CA  . GLY A 1 342 ? 10.082  -7.516  -13.371  1.00 19.72  ? 335  GLY A CA  1 
ATOM   2544  C C   . GLY A 1 342 ? 11.308  -7.456  -12.481  1.00 22.26  ? 335  GLY A C   1 
ATOM   2545  O O   . GLY A 1 342 ? 11.646  -8.499  -11.885  1.00 26.66  ? 335  GLY A O   1 
ATOM   2546  N N   . ASN A 1 343 ? 11.939  -6.276  -12.350  1.00 21.39  ? 336  ASN A N   1 
ATOM   2547  C CA  . ASN A 1 343 ? 13.081  -6.071  -11.423  1.00 19.30  ? 336  ASN A CA  1 
ATOM   2548  C C   . ASN A 1 343 ? 12.611  -6.330  -9.993   1.00 19.56  ? 336  ASN A C   1 
ATOM   2549  O O   . ASN A 1 343 ? 11.432  -6.175  -9.643   1.00 18.40  ? 336  ASN A O   1 
ATOM   2550  C CB  . ASN A 1 343 ? 13.767  -4.713  -11.585  1.00 18.40  ? 336  ASN A CB  1 
ATOM   2551  C CG  . ASN A 1 343 ? 12.950  -3.530  -11.117  1.00 18.28  ? 336  ASN A CG  1 
ATOM   2552  O OD1 . ASN A 1 343 ? 12.882  -3.239  -9.919   1.00 16.94  ? 336  ASN A OD1 1 
ATOM   2553  N ND2 . ASN A 1 343 ? 12.358  -2.824  -12.071  1.00 19.03  ? 336  ASN A ND2 1 
ATOM   2554  N N   . PRO A 1 344 ? 13.540  -6.806  -9.140   1.00 18.88  ? 337  PRO A N   1 
ATOM   2555  C CA  . PRO A 1 344 ? 13.229  -7.099  -7.741   1.00 17.94  ? 337  PRO A CA  1 
ATOM   2556  C C   . PRO A 1 344 ? 12.619  -5.969  -6.894   1.00 17.62  ? 337  PRO A C   1 
ATOM   2557  O O   . PRO A 1 344 ? 11.744  -6.298  -6.134   1.00 16.78  ? 337  PRO A O   1 
ATOM   2558  C CB  . PRO A 1 344 ? 14.608  -7.480  -7.195   1.00 18.20  ? 337  PRO A CB  1 
ATOM   2559  C CG  . PRO A 1 344 ? 15.338  -8.070  -8.375   1.00 18.26  ? 337  PRO A CG  1 
ATOM   2560  C CD  . PRO A 1 344 ? 14.911  -7.186  -9.521   1.00 18.13  ? 337  PRO A CD  1 
ATOM   2561  N N   . LEU A 1 345 ? 13.076  -4.711  -7.000   1.00 17.30  ? 338  LEU A N   1 
ATOM   2562  C CA  . LEU A 1 345 ? 12.429  -3.573  -6.272   1.00 17.12  ? 338  LEU A CA  1 
ATOM   2563  C C   . LEU A 1 345 ? 10.954  -3.499  -6.672   1.00 16.80  ? 338  LEU A C   1 
ATOM   2564  O O   . LEU A 1 345 ? 10.084  -3.436  -5.801   1.00 15.63  ? 338  LEU A O   1 
ATOM   2565  C CB  . LEU A 1 345 ? 13.080  -2.236  -6.631   1.00 17.62  ? 338  LEU A CB  1 
ATOM   2566  C CG  . LEU A 1 345 ? 14.439  -1.940  -6.006   1.00 18.67  ? 338  LEU A CG  1 
ATOM   2567  C CD1 . LEU A 1 345 ? 14.723  -0.445  -6.094   1.00 19.04  ? 338  LEU A CD1 1 
ATOM   2568  C CD2 . LEU A 1 345 ? 14.533  -2.407  -4.542   1.00 19.06  ? 338  LEU A CD2 1 
ATOM   2569  N N   . ALA A 1 346 ? 10.693  -3.448  -7.967   1.00 16.66  ? 339  ALA A N   1 
ATOM   2570  C CA  . ALA A 1 346 ? 9.320   -3.305  -8.471   1.00 17.68  ? 339  ALA A CA  1 
ATOM   2571  C C   . ALA A 1 346 ? 8.492   -4.489  -7.966   1.00 17.34  ? 339  ALA A C   1 
ATOM   2572  O O   . ALA A 1 346 ? 7.390   -4.222  -7.483   1.00 16.98  ? 339  ALA A O   1 
ATOM   2573  C CB  . ALA A 1 346 ? 9.312   -3.197  -9.972   1.00 18.36  ? 339  ALA A CB  1 
ATOM   2574  N N   . CYS A 1 347 ? 8.998   -5.729  -8.065   1.00 17.99  ? 340  CYS A N   1 
ATOM   2575  C CA  . CYS A 1 347 ? 8.264   -6.966  -7.660   1.00 18.43  ? 340  CYS A CA  1 
ATOM   2576  C C   . CYS A 1 347 ? 7.977   -6.918  -6.152   1.00 18.64  ? 340  CYS A C   1 
ATOM   2577  O O   . CYS A 1 347 ? 6.803   -7.156  -5.740   1.00 20.23  ? 340  CYS A O   1 
ATOM   2578  C CB  . CYS A 1 347 ? 9.030   -8.243  -7.972   1.00 19.31  ? 340  CYS A CB  1 
ATOM   2579  S SG  . CYS A 1 347 ? 9.081   -8.660  -9.730   1.00 21.96  ? 340  CYS A SG  1 
ATOM   2580  N N   . ALA A 1 348 ? 8.993   -6.590  -5.362   1.00 16.51  ? 341  ALA A N   1 
ATOM   2581  C CA  . ALA A 1 348 ? 8.860   -6.366  -3.909   1.00 17.05  ? 341  ALA A CA  1 
ATOM   2582  C C   . ALA A 1 348 ? 7.710   -5.383  -3.661   1.00 17.24  ? 341  ALA A C   1 
ATOM   2583  O O   . ALA A 1 348 ? 6.861   -5.700  -2.823   1.00 18.43  ? 341  ALA A O   1 
ATOM   2584  C CB  . ALA A 1 348 ? 10.153  -5.868  -3.322   1.00 16.01  ? 341  ALA A CB  1 
ATOM   2585  N N   . ALA A 1 349 ? 7.675   -4.253  -4.377   1.00 17.26  ? 342  ALA A N   1 
ATOM   2586  C CA  . ALA A 1 349 ? 6.689   -3.164  -4.170   1.00 16.86  ? 342  ALA A CA  1 
ATOM   2587  C C   . ALA A 1 349 ? 5.285   -3.693  -4.485   1.00 16.78  ? 342  ALA A C   1 
ATOM   2588  O O   . ALA A 1 349 ? 4.349   -3.438  -3.698   1.00 17.33  ? 342  ALA A O   1 
ATOM   2589  C CB  . ALA A 1 349 ? 7.027   -1.962  -5.014   1.00 15.75  ? 342  ALA A CB  1 
ATOM   2590  N N   . ALA A 1 350 ? 5.158   -4.442  -5.573   1.00 16.55  ? 343  ALA A N   1 
ATOM   2591  C CA  . ALA A 1 350 ? 3.870   -5.006  -6.024   1.00 17.70  ? 343  ALA A CA  1 
ATOM   2592  C C   . ALA A 1 350 ? 3.420   -6.070  -5.020   1.00 17.66  ? 343  ALA A C   1 
ATOM   2593  O O   . ALA A 1 350 ? 2.220   -6.076  -4.698   1.00 17.50  ? 343  ALA A O   1 
ATOM   2594  C CB  . ALA A 1 350 ? 3.961   -5.562  -7.429   1.00 16.98  ? 343  ALA A CB  1 
ATOM   2595  N N   . LEU A 1 351 ? 4.334   -6.932  -4.561   1.00 17.15  ? 344  LEU A N   1 
ATOM   2596  C CA  . LEU A 1 351 ? 3.975   -8.062  -3.676   1.00 17.48  ? 344  LEU A CA  1 
ATOM   2597  C C   . LEU A 1 351 ? 3.464   -7.479  -2.366   1.00 19.13  ? 344  LEU A C   1 
ATOM   2598  O O   . LEU A 1 351 ? 2.446   -8.000  -1.820   1.00 19.20  ? 344  LEU A O   1 
ATOM   2599  C CB  . LEU A 1 351 ? 5.201   -8.936  -3.450   1.00 17.36  ? 344  LEU A CB  1 
ATOM   2600  C CG  . LEU A 1 351 ? 5.541   -9.866  -4.605   1.00 17.22  ? 344  LEU A CG  1 
ATOM   2601  C CD1 . LEU A 1 351 ? 7.012   -10.275 -4.559   1.00 17.39  ? 344  LEU A CD1 1 
ATOM   2602  C CD2 . LEU A 1 351 ? 4.628   -11.081 -4.570   1.00 16.92  ? 344  LEU A CD2 1 
ATOM   2603  N N   . ALA A 1 352 ? 4.127   -6.415  -1.896   1.00 18.52  ? 345  ALA A N   1 
ATOM   2604  C CA  . ALA A 1 352 ? 3.712   -5.666  -0.687   1.00 18.69  ? 345  ALA A CA  1 
ATOM   2605  C C   . ALA A 1 352 ? 2.304   -5.094  -0.916   1.00 18.19  ? 345  ALA A C   1 
ATOM   2606  O O   . ALA A 1 352 ? 1.455   -5.259  -0.045   1.00 17.85  ? 345  ALA A O   1 
ATOM   2607  C CB  . ALA A 1 352 ? 4.703   -4.576  -0.391   1.00 17.85  ? 345  ALA A CB  1 
ATOM   2608  N N   . THR A 1 353 ? 2.089   -4.448  -2.066   1.00 17.53  ? 346  THR A N   1 
ATOM   2609  C CA  . THR A 1 353 ? 0.835   -3.741  -2.398   1.00 17.57  ? 346  THR A CA  1 
ATOM   2610  C C   . THR A 1 353 ? -0.323  -4.736  -2.350   1.00 18.27  ? 346  THR A C   1 
ATOM   2611  O O   . THR A 1 353 ? -1.336  -4.422  -1.704   1.00 19.20  ? 346  THR A O   1 
ATOM   2612  C CB  . THR A 1 353 ? 0.927   -3.067  -3.762   1.00 17.94  ? 346  THR A CB  1 
ATOM   2613  O OG1 . THR A 1 353 ? 2.082   -2.231  -3.721   1.00 17.34  ? 346  THR A OG1 1 
ATOM   2614  C CG2 . THR A 1 353 ? -0.330  -2.286  -4.087   1.00 17.62  ? 346  THR A CG2 1 
ATOM   2615  N N   . ILE A 1 354 ? -0.181  -5.883  -3.012   1.00 18.50  ? 347  ILE A N   1 
ATOM   2616  C CA  . ILE A 1 354 ? -1.199  -6.973  -2.993   1.00 19.54  ? 347  ILE A CA  1 
ATOM   2617  C C   . ILE A 1 354 ? -1.426  -7.416  -1.547   1.00 19.16  ? 347  ILE A C   1 
ATOM   2618  O O   . ILE A 1 354 ? -2.583  -7.560  -1.142   1.00 17.82  ? 347  ILE A O   1 
ATOM   2619  C CB  . ILE A 1 354 ? -0.760  -8.159  -3.861   1.00 20.12  ? 347  ILE A CB  1 
ATOM   2620  C CG1 . ILE A 1 354 ? -0.823  -7.804  -5.340   1.00 20.08  ? 347  ILE A CG1 1 
ATOM   2621  C CG2 . ILE A 1 354 ? -1.577  -9.397  -3.557   1.00 20.55  ? 347  ILE A CG2 1 
ATOM   2622  C CD1 . ILE A 1 354 ? 0.088   -8.647  -6.200   1.00 20.65  ? 347  ILE A CD1 1 
ATOM   2623  N N   . ASN A 1 355 ? -0.356  -7.659  -0.806   1.00 18.64  ? 348  ASN A N   1 
ATOM   2624  C CA  . ASN A 1 355 ? -0.486  -8.075  0.612    1.00 20.44  ? 348  ASN A CA  1 
ATOM   2625  C C   . ASN A 1 355 ? -1.343  -7.059  1.387    1.00 18.81  ? 348  ASN A C   1 
ATOM   2626  O O   . ASN A 1 355 ? -2.231  -7.499  2.117    1.00 17.67  ? 348  ASN A O   1 
ATOM   2627  C CB  . ASN A 1 355 ? 0.863   -8.254  1.299    1.00 20.49  ? 348  ASN A CB  1 
ATOM   2628  C CG  . ASN A 1 355 ? 0.686   -8.947  2.619    1.00 21.99  ? 348  ASN A CG  1 
ATOM   2629  O OD1 . ASN A 1 355 ? 0.668   -8.302  3.668    1.00 26.45  ? 348  ASN A OD1 1 
ATOM   2630  N ND2 . ASN A 1 355 ? 0.489   -10.252 2.558    1.00 22.78  ? 348  ASN A ND2 1 
ATOM   2631  N N   . VAL A 1 356 ? -1.071  -5.763  1.210    1.00 17.66  ? 349  VAL A N   1 
ATOM   2632  C CA  . VAL A 1 356 ? -1.757  -4.647  1.922    1.00 16.86  ? 349  VAL A CA  1 
ATOM   2633  C C   . VAL A 1 356 ? -3.241  -4.630  1.517    1.00 18.71  ? 349  VAL A C   1 
ATOM   2634  O O   . VAL A 1 356 ? -4.098  -4.599  2.404    1.00 18.88  ? 349  VAL A O   1 
ATOM   2635  C CB  . VAL A 1 356 ? -1.082  -3.295  1.639    1.00 15.15  ? 349  VAL A CB  1 
ATOM   2636  C CG1 . VAL A 1 356 ? -1.946  -2.112  2.025    1.00 14.40  ? 349  VAL A CG1 1 
ATOM   2637  C CG2 . VAL A 1 356 ? 0.256   -3.217  2.331    1.00 15.57  ? 349  VAL A CG2 1 
ATOM   2638  N N   . LEU A 1 357 ? -3.538  -4.643  0.219    1.00 20.08  ? 350  LEU A N   1 
ATOM   2639  C CA  . LEU A 1 357 ? -4.931  -4.521  -0.290   1.00 20.79  ? 350  LEU A CA  1 
ATOM   2640  C C   . LEU A 1 357 ? -5.783  -5.667  0.257    1.00 21.50  ? 350  LEU A C   1 
ATOM   2641  O O   . LEU A 1 357 ? -6.937  -5.387  0.644    1.00 24.60  ? 350  LEU A O   1 
ATOM   2642  C CB  . LEU A 1 357 ? -4.939  -4.524  -1.821   1.00 21.20  ? 350  LEU A CB  1 
ATOM   2643  C CG  . LEU A 1 357 ? -4.389  -3.263  -2.490   1.00 21.66  ? 350  LEU A CG  1 
ATOM   2644  C CD1 . LEU A 1 357 ? -4.113  -3.500  -3.967   1.00 22.34  ? 350  LEU A CD1 1 
ATOM   2645  C CD2 . LEU A 1 357 ? -5.318  -2.074  -2.335   1.00 20.45  ? 350  LEU A CD2 1 
ATOM   2646  N N   . LEU A 1 358 ? -5.234  -6.887  0.297    1.00 21.54  ? 351  LEU A N   1 
ATOM   2647  C CA  . LEU A 1 358 ? -5.971  -8.101  0.738    1.00 23.22  ? 351  LEU A CA  1 
ATOM   2648  C C   . LEU A 1 358 ? -6.109  -8.099  2.270    1.00 25.07  ? 351  LEU A C   1 
ATOM   2649  O O   . LEU A 1 358 ? -7.255  -8.236  2.748    1.00 22.43  ? 351  LEU A O   1 
ATOM   2650  C CB  . LEU A 1 358 ? -5.262  -9.347  0.204    1.00 22.43  ? 351  LEU A CB  1 
ATOM   2651  C CG  . LEU A 1 358 ? -5.321  -9.492  -1.329   1.00 22.91  ? 351  LEU A CG  1 
ATOM   2652  C CD1 . LEU A 1 358 ? -4.693  -10.792 -1.816   1.00 20.98  ? 351  LEU A CD1 1 
ATOM   2653  C CD2 . LEU A 1 358 ? -6.757  -9.403  -1.831   1.00 24.02  ? 351  LEU A CD2 1 
ATOM   2654  N N   . GLU A 1 359 ? -5.003  -7.916  3.001    1.00 27.96  ? 352  GLU A N   1 
ATOM   2655  C CA  . GLU A 1 359 ? -4.965  -7.892  4.496    1.00 33.31  ? 352  GLU A CA  1 
ATOM   2656  C C   . GLU A 1 359 ? -6.003  -6.925  5.049    1.00 30.16  ? 352  GLU A C   1 
ATOM   2657  O O   . GLU A 1 359 ? -6.679  -7.320  5.997    1.00 28.22  ? 352  GLU A O   1 
ATOM   2658  C CB  . GLU A 1 359 ? -3.643  -7.376  5.074    1.00 41.62  ? 352  GLU A CB  1 
ATOM   2659  C CG  . GLU A 1 359 ? -2.571  -8.436  5.246    1.00 49.29  ? 352  GLU A CG  1 
ATOM   2660  C CD  . GLU A 1 359 ? -2.618  -9.215  6.543    1.00 52.49  ? 352  GLU A CD  1 
ATOM   2661  O OE1 . GLU A 1 359 ? -3.730  -9.677  6.915    1.00 60.41  ? 352  GLU A OE1 1 
ATOM   2662  O OE2 . GLU A 1 359 ? -1.536  -9.357  7.173    1.00 55.74  ? 352  GLU A OE2 1 
ATOM   2663  N N   . GLN A 1 360 ? -6.071  -5.706  4.493    1.00 28.72  ? 353  GLN A N   1 
ATOM   2664  C CA  . GLN A 1 360 ? -6.891  -4.591  5.033    1.00 27.29  ? 353  GLN A CA  1 
ATOM   2665  C C   . GLN A 1 360 ? -8.218  -4.434  4.291    1.00 25.89  ? 353  GLN A C   1 
ATOM   2666  O O   . GLN A 1 360 ? -8.931  -3.483  4.613    1.00 26.23  ? 353  GLN A O   1 
ATOM   2667  C CB  . GLN A 1 360 ? -6.152  -3.266  4.931    1.00 28.67  ? 353  GLN A CB  1 
ATOM   2668  C CG  . GLN A 1 360 ? -4.804  -3.282  5.632    1.00 29.89  ? 353  GLN A CG  1 
ATOM   2669  C CD  . GLN A 1 360 ? -4.226  -1.896  5.661    1.00 30.71  ? 353  GLN A CD  1 
ATOM   2670  O OE1 . GLN A 1 360 ? -4.946  -0.918  5.837    1.00 33.20  ? 353  GLN A OE1 1 
ATOM   2671  N NE2 . GLN A 1 360 ? -2.919  -1.801  5.497    1.00 31.77  ? 353  GLN A NE2 1 
ATOM   2672  N N   A ASN A 1 361 ? -8.540  -5.331  3.352    0.51 25.39  ? 354  ASN A N   1 
ATOM   2673  N N   B ASN A 1 361 ? -8.536  -5.327  3.346    0.49 24.58  ? 354  ASN A N   1 
ATOM   2674  C CA  A ASN A 1 361 ? -9.785  -5.304  2.539    0.51 24.97  ? 354  ASN A CA  1 
ATOM   2675  C CA  B ASN A 1 361 ? -9.814  -5.308  2.581    0.49 23.68  ? 354  ASN A CA  1 
ATOM   2676  C C   A ASN A 1 361 ? -10.056 -3.884  2.026    0.51 24.91  ? 354  ASN A C   1 
ATOM   2677  C C   B ASN A 1 361 ? -10.061 -3.891  2.025    0.49 24.15  ? 354  ASN A C   1 
ATOM   2678  O O   A ASN A 1 361 ? -11.203 -3.408  2.119    0.51 26.87  ? 354  ASN A O   1 
ATOM   2679  O O   B ASN A 1 361 ? -11.204 -3.404  2.118    0.49 26.00  ? 354  ASN A O   1 
ATOM   2680  C CB  A ASN A 1 361 ? -11.010 -5.842  3.271    0.51 24.87  ? 354  ASN A CB  1 
ATOM   2681  C CB  B ASN A 1 361 ? -11.008 -5.752  3.448    0.49 22.65  ? 354  ASN A CB  1 
ATOM   2682  C CG  A ASN A 1 361 ? -12.069 -6.309  2.281    0.51 24.56  ? 354  ASN A CG  1 
ATOM   2683  C CG  B ASN A 1 361 ? -10.991 -7.205  3.891    0.49 21.34  ? 354  ASN A CG  1 
ATOM   2684  O OD1 A ASN A 1 361 ? -12.010 -5.989  1.091    0.51 23.50  ? 354  ASN A OD1 1 
ATOM   2685  O OD1 B ASN A 1 361 ? -11.444 -8.092  3.174    0.49 20.84  ? 354  ASN A OD1 1 
ATOM   2686  N ND2 A ASN A 1 361 ? -13.033 -7.083  2.739    0.51 23.89  ? 354  ASN A ND2 1 
ATOM   2687  N ND2 B ASN A 1 361 ? -10.474 -7.466  5.078    0.49 20.86  ? 354  ASN A ND2 1 
ATOM   2688  N N   . LEU A 1 362 ? -9.042  -3.243  1.456    1.00 24.50  ? 355  LEU A N   1 
ATOM   2689  C CA  . LEU A 1 362 ? -9.159  -1.864  0.909    1.00 23.85  ? 355  LEU A CA  1 
ATOM   2690  C C   . LEU A 1 362 ? -10.112 -1.798  -0.288   1.00 23.77  ? 355  LEU A C   1 
ATOM   2691  O O   . LEU A 1 362 ? -10.705 -0.743  -0.517   1.00 26.40  ? 355  LEU A O   1 
ATOM   2692  C CB  . LEU A 1 362 ? -7.760  -1.357  0.537    1.00 23.19  ? 355  LEU A CB  1 
ATOM   2693  C CG  . LEU A 1 362 ? -7.003  -0.717  1.693    1.00 22.73  ? 355  LEU A CG  1 
ATOM   2694  C CD1 . LEU A 1 362 ? -5.515  -0.635  1.405    1.00 22.66  ? 355  LEU A CD1 1 
ATOM   2695  C CD2 . LEU A 1 362 ? -7.567  0.656   2.024    1.00 22.56  ? 355  LEU A CD2 1 
ATOM   2696  N N   . PRO A 1 363 ? -10.298 -2.866  -1.104   1.00 22.98  ? 356  PRO A N   1 
ATOM   2697  C CA  . PRO A 1 363 ? -11.372 -2.876  -2.101   1.00 23.81  ? 356  PRO A CA  1 
ATOM   2698  C C   . PRO A 1 363 ? -12.731 -2.558  -1.453   1.00 22.73  ? 356  PRO A C   1 
ATOM   2699  O O   . PRO A 1 363 ? -13.421 -1.645  -1.890   1.00 24.66  ? 356  PRO A O   1 
ATOM   2700  C CB  . PRO A 1 363 ? -11.309 -4.294  -2.702   1.00 22.62  ? 356  PRO A CB  1 
ATOM   2701  C CG  . PRO A 1 363 ? -9.853  -4.665  -2.552   1.00 21.61  ? 356  PRO A CG  1 
ATOM   2702  C CD  . PRO A 1 363 ? -9.464  -4.072  -1.208   1.00 22.76  ? 356  PRO A CD  1 
ATOM   2703  N N   . ALA A 1 364 ? -13.077 -3.280  -0.399   1.00 20.64  ? 357  ALA A N   1 
ATOM   2704  C CA  . ALA A 1 364 ? -14.327 -3.030  0.339    1.00 19.68  ? 357  ALA A CA  1 
ATOM   2705  C C   . ALA A 1 364 ? -14.353 -1.575  0.839    1.00 19.52  ? 357  ALA A C   1 
ATOM   2706  O O   . ALA A 1 364 ? -15.428 -0.955  0.774    1.00 21.24  ? 357  ALA A O   1 
ATOM   2707  C CB  . ALA A 1 364 ? -14.451 -4.037  1.444    1.00 19.90  ? 357  ALA A CB  1 
ATOM   2708  N N   . GLN A 1 365 ? -13.229 -1.020  1.306    1.00 19.15  ? 358  GLN A N   1 
ATOM   2709  C CA  . GLN A 1 365 ? -13.196 0.371   1.837    1.00 19.40  ? 358  GLN A CA  1 
ATOM   2710  C C   . GLN A 1 365 ? -13.494 1.353   0.706    1.00 19.40  ? 358  GLN A C   1 
ATOM   2711  O O   . GLN A 1 365 ? -14.223 2.338   0.929    1.00 19.37  ? 358  GLN A O   1 
ATOM   2712  C CB  . GLN A 1 365 ? -11.852 0.688   2.480    1.00 20.67  ? 358  GLN A CB  1 
ATOM   2713  C CG  . GLN A 1 365 ? -11.622 -0.069  3.779    1.00 22.74  ? 358  GLN A CG  1 
ATOM   2714  C CD  . GLN A 1 365 ? -10.369 0.388   4.481    1.00 26.12  ? 358  GLN A CD  1 
ATOM   2715  O OE1 . GLN A 1 365 ? -10.130 1.582   4.669    1.00 30.43  ? 358  GLN A OE1 1 
ATOM   2716  N NE2 . GLN A 1 365 ? -9.541  -0.572  4.865    1.00 28.52  ? 358  GLN A NE2 1 
ATOM   2717  N N   . ALA A 1 366 ? -12.932 1.094   -0.468   1.00 19.18  ? 359  ALA A N   1 
ATOM   2718  C CA  . ALA A 1 366 ? -13.082 1.973   -1.638   1.00 20.99  ? 359  ALA A CA  1 
ATOM   2719  C C   . ALA A 1 366 ? -14.578 2.059   -1.987   1.00 22.58  ? 359  ALA A C   1 
ATOM   2720  O O   . ALA A 1 366 ? -15.075 3.174   -2.248   1.00 19.01  ? 359  ALA A O   1 
ATOM   2721  C CB  . ALA A 1 366 ? -12.240 1.450   -2.776   1.00 20.64  ? 359  ALA A CB  1 
ATOM   2722  N N   . GLU A 1 367 ? -15.267 0.915   -1.963   1.00 27.21  ? 360  GLU A N   1 
ATOM   2723  C CA  . GLU A 1 367 ? -16.734 0.816   -2.197   1.00 32.27  ? 360  GLU A CA  1 
ATOM   2724  C C   . GLU A 1 367 ? -17.464 1.756   -1.229   1.00 30.93  ? 360  GLU A C   1 
ATOM   2725  O O   . GLU A 1 367 ? -18.247 2.624   -1.713   1.00 25.22  ? 360  GLU A O   1 
ATOM   2726  C CB  . GLU A 1 367 ? -17.220 -0.625  -2.021   1.00 39.64  ? 360  GLU A CB  1 
ATOM   2727  C CG  . GLU A 1 367 ? -18.687 -0.850  -2.381   1.00 46.16  ? 360  GLU A CG  1 
ATOM   2728  C CD  . GLU A 1 367 ? -19.129 -2.313  -2.348   1.00 53.60  ? 360  GLU A CD  1 
ATOM   2729  O OE1 . GLU A 1 367 ? -18.243 -3.203  -2.398   1.00 67.28  ? 360  GLU A OE1 1 
ATOM   2730  O OE2 . GLU A 1 367 ? -20.358 -2.581  -2.279   1.00 53.14  ? 360  GLU A OE2 1 
ATOM   2731  N N   . GLN A 1 368 ? -17.203 1.601   0.081    1.00 28.93  ? 361  GLN A N   1 
ATOM   2732  C CA  . GLN A 1 368 ? -17.948 2.324   1.132    1.00 29.57  ? 361  GLN A CA  1 
ATOM   2733  C C   . GLN A 1 368 ? -17.655 3.816   0.996    1.00 25.52  ? 361  GLN A C   1 
ATOM   2734  O O   . GLN A 1 368 ? -18.608 4.613   1.012    1.00 25.88  ? 361  GLN A O   1 
ATOM   2735  C CB  . GLN A 1 368 ? -17.579 1.808   2.519    1.00 35.52  ? 361  GLN A CB  1 
ATOM   2736  C CG  . GLN A 1 368 ? -18.561 2.245   3.598    1.00 40.79  ? 361  GLN A CG  1 
ATOM   2737  C CD  . GLN A 1 368 ? -17.983 3.259   4.558    1.00 45.88  ? 361  GLN A CD  1 
ATOM   2738  O OE1 . GLN A 1 368 ? -16.910 3.045   5.121    1.00 42.75  ? 361  GLN A OE1 1 
ATOM   2739  N NE2 . GLN A 1 368 ? -18.717 4.342   4.797    1.00 51.76  ? 361  GLN A NE2 1 
ATOM   2740  N N   . LYS A 1 369 ? -16.383 4.166   0.858    1.00 22.41  ? 362  LYS A N   1 
ATOM   2741  C CA  . LYS A 1 369 ? -15.932 5.577   0.889    1.00 24.08  ? 362  LYS A CA  1 
ATOM   2742  C C   . LYS A 1 369 ? -16.345 6.267   -0.415   1.00 24.38  ? 362  LYS A C   1 
ATOM   2743  O O   . LYS A 1 369 ? -16.703 7.445   -0.369   1.00 23.01  ? 362  LYS A O   1 
ATOM   2744  C CB  . LYS A 1 369 ? -14.419 5.640   1.115    1.00 23.91  ? 362  LYS A CB  1 
ATOM   2745  C CG  . LYS A 1 369 ? -13.973 5.198   2.492    1.00 24.69  ? 362  LYS A CG  1 
ATOM   2746  C CD  . LYS A 1 369 ? -12.484 4.963   2.589    1.00 26.41  ? 362  LYS A CD  1 
ATOM   2747  C CE  . LYS A 1 369 ? -12.096 4.418   3.944    1.00 27.67  ? 362  LYS A CE  1 
ATOM   2748  N NZ  . LYS A 1 369 ? -10.624 4.395   4.116    1.00 30.44  ? 362  LYS A NZ  1 
ATOM   2749  N N   . GLY A 1 370 ? -16.279 5.551   -1.538   1.00 26.15  ? 363  GLY A N   1 
ATOM   2750  C CA  . GLY A 1 370 ? -16.739 6.047   -2.842   1.00 25.03  ? 363  GLY A CA  1 
ATOM   2751  C C   . GLY A 1 370 ? -18.233 6.326   -2.834   1.00 26.73  ? 363  GLY A C   1 
ATOM   2752  O O   . GLY A 1 370 ? -18.646 7.408   -3.307   1.00 25.46  ? 363  GLY A O   1 
ATOM   2753  N N   . ASP A 1 371 ? -19.020 5.393   -2.296   1.00 28.23  ? 364  ASP A N   1 
ATOM   2754  C CA  . ASP A 1 371 ? -20.483 5.584   -2.126   1.00 27.11  ? 364  ASP A CA  1 
ATOM   2755  C C   . ASP A 1 371 ? -20.725 6.871   -1.330   1.00 24.29  ? 364  ASP A C   1 
ATOM   2756  O O   . ASP A 1 371 ? -21.582 7.693   -1.736   1.00 23.12  ? 364  ASP A O   1 
ATOM   2757  C CB  . ASP A 1 371 ? -21.125 4.370   -1.447   1.00 29.40  ? 364  ASP A CB  1 
ATOM   2758  C CG  . ASP A 1 371 ? -21.220 3.134   -2.318   1.00 32.88  ? 364  ASP A CG  1 
ATOM   2759  O OD1 . ASP A 1 371 ? -20.935 3.263   -3.551   1.00 36.55  ? 364  ASP A OD1 1 
ATOM   2760  O OD2 . ASP A 1 371 ? -21.579 2.054   -1.754   1.00 33.42  ? 364  ASP A OD2 1 
ATOM   2761  N N   A MET A 1 372 ? -19.984 7.034   -0.229   0.57 23.53  ? 365  MET A N   1 
ATOM   2762  N N   B MET A 1 372 ? -19.985 7.030   -0.233   0.43 24.62  ? 365  MET A N   1 
ATOM   2763  C CA  A MET A 1 372 ? -20.103 8.182   0.703    0.57 23.37  ? 365  MET A CA  1 
ATOM   2764  C CA  B MET A 1 372 ? -20.111 8.180   0.693    0.43 25.02  ? 365  MET A CA  1 
ATOM   2765  C C   A MET A 1 372 ? -19.756 9.468   -0.056   0.57 23.13  ? 365  MET A C   1 
ATOM   2766  C C   B MET A 1 372 ? -19.757 9.470   -0.058   0.43 24.04  ? 365  MET A C   1 
ATOM   2767  O O   A MET A 1 372 ? -20.588 10.402  -0.051   0.57 23.63  ? 365  MET A O   1 
ATOM   2768  O O   B MET A 1 372 ? -20.589 10.407  -0.054   0.43 24.38  ? 365  MET A O   1 
ATOM   2769  C CB  A MET A 1 372 ? -19.171 7.994   1.907    0.57 23.59  ? 365  MET A CB  1 
ATOM   2770  C CB  B MET A 1 372 ? -19.184 7.997   1.894    0.43 26.51  ? 365  MET A CB  1 
ATOM   2771  C CG  A MET A 1 372 ? -19.188 9.146   2.912    0.57 24.31  ? 365  MET A CG  1 
ATOM   2772  C CG  B MET A 1 372 ? -19.307 9.109   2.907    0.43 28.25  ? 365  MET A CG  1 
ATOM   2773  S SD  A MET A 1 372 ? -18.215 8.896   4.467    0.57 24.76  ? 365  MET A SD  1 
ATOM   2774  S SD  B MET A 1 372 ? -18.498 10.646  2.397    0.43 30.95  ? 365  MET A SD  1 
ATOM   2775  C CE  A MET A 1 372 ? -16.891 7.834   3.892    0.57 24.37  ? 365  MET A CE  1 
ATOM   2776  C CE  B MET A 1 372 ? -18.257 11.422  3.998    0.43 31.29  ? 365  MET A CE  1 
ATOM   2777  N N   . LEU A 1 373 ? -18.592 9.491   -0.712   1.00 22.53  ? 366  LEU A N   1 
ATOM   2778  C CA  . LEU A 1 373 ? -18.071 10.676  -1.436   1.00 22.39  ? 366  LEU A CA  1 
ATOM   2779  C C   . LEU A 1 373 ? -18.975 11.038  -2.614   1.00 23.48  ? 366  LEU A C   1 
ATOM   2780  O O   . LEU A 1 373 ? -19.242 12.250  -2.793   1.00 24.30  ? 366  LEU A O   1 
ATOM   2781  C CB  . LEU A 1 373 ? -16.652 10.373  -1.925   1.00 22.08  ? 366  LEU A CB  1 
ATOM   2782  C CG  . LEU A 1 373 ? -15.566 10.520  -0.863   1.00 20.83  ? 366  LEU A CG  1 
ATOM   2783  C CD1 . LEU A 1 373 ? -14.218 10.105  -1.419   1.00 21.72  ? 366  LEU A CD1 1 
ATOM   2784  C CD2 . LEU A 1 373 ? -15.513 11.947  -0.345   1.00 20.01  ? 366  LEU A CD2 1 
ATOM   2785  N N   . LEU A 1 374 ? -19.396 10.040  -3.400   1.00 24.68  ? 367  LEU A N   1 
ATOM   2786  C CA  . LEU A 1 374 ? -20.241 10.267  -4.600   1.00 25.54  ? 367  LEU A CA  1 
ATOM   2787  C C   . LEU A 1 374 ? -21.577 10.880  -4.157   1.00 26.20  ? 367  LEU A C   1 
ATOM   2788  O O   . LEU A 1 374 ? -22.024 11.849  -4.819   1.00 22.63  ? 367  LEU A O   1 
ATOM   2789  C CB  . LEU A 1 374 ? -20.432 8.943   -5.340   1.00 25.71  ? 367  LEU A CB  1 
ATOM   2790  C CG  . LEU A 1 374 ? -21.201 9.036   -6.664   1.00 25.49  ? 367  LEU A CG  1 
ATOM   2791  C CD1 . LEU A 1 374 ? -20.604 10.086  -7.598   1.00 24.75  ? 367  LEU A CD1 1 
ATOM   2792  C CD2 . LEU A 1 374 ? -21.258 7.674   -7.363   1.00 24.68  ? 367  LEU A CD2 1 
ATOM   2793  N N   . ASP A 1 375 ? -22.169 10.353  -3.073   1.00 29.03  ? 368  ASP A N   1 
ATOM   2794  C CA  . ASP A 1 375 ? -23.433 10.893  -2.498   1.00 32.29  ? 368  ASP A CA  1 
ATOM   2795  C C   . ASP A 1 375 ? -23.207 12.364  -2.171   1.00 30.22  ? 368  ASP A C   1 
ATOM   2796  O O   . ASP A 1 375 ? -24.017 13.202  -2.587   1.00 28.65  ? 368  ASP A O   1 
ATOM   2797  C CB  . ASP A 1 375 ? -23.906 10.123  -1.271   1.00 36.87  ? 368  ASP A CB  1 
ATOM   2798  C CG  . ASP A 1 375 ? -24.579 8.824   -1.659   1.00 44.15  ? 368  ASP A CG  1 
ATOM   2799  O OD1 . ASP A 1 375 ? -24.589 8.486   -2.864   1.00 49.96  ? 368  ASP A OD1 1 
ATOM   2800  O OD2 . ASP A 1 375 ? -25.087 8.168   -0.759   1.00 55.19  ? 368  ASP A OD2 1 
ATOM   2801  N N   . GLY A 1 376 ? -22.116 12.660  -1.485   1.00 29.53  ? 369  GLY A N   1 
ATOM   2802  C CA  . GLY A 1 376 ? -21.748 14.045  -1.154   1.00 29.68  ? 369  GLY A CA  1 
ATOM   2803  C C   . GLY A 1 376 ? -21.709 14.920  -2.396   1.00 28.38  ? 369  GLY A C   1 
ATOM   2804  O O   . GLY A 1 376 ? -22.281 16.026  -2.370   1.00 30.00  ? 369  GLY A O   1 
ATOM   2805  N N   . PHE A 1 377 ? -21.063 14.451  -3.458   1.00 27.85  ? 370  PHE A N   1 
ATOM   2806  C CA  . PHE A 1 377 ? -20.842 15.243  -4.693   1.00 27.30  ? 370  PHE A CA  1 
ATOM   2807  C C   . PHE A 1 377 ? -22.160 15.421  -5.437   1.00 29.51  ? 370  PHE A C   1 
ATOM   2808  O O   . PHE A 1 377 ? -22.452 16.556  -5.863   1.00 33.33  ? 370  PHE A O   1 
ATOM   2809  C CB  . PHE A 1 377 ? -19.789 14.584  -5.573   1.00 25.07  ? 370  PHE A CB  1 
ATOM   2810  C CG  . PHE A 1 377 ? -18.407 14.600  -4.975   1.00 23.11  ? 370  PHE A CG  1 
ATOM   2811  C CD1 . PHE A 1 377 ? -17.916 15.733  -4.349   1.00 22.33  ? 370  PHE A CD1 1 
ATOM   2812  C CD2 . PHE A 1 377 ? -17.587 13.488  -5.080   1.00 23.06  ? 370  PHE A CD2 1 
ATOM   2813  C CE1 . PHE A 1 377 ? -16.643 15.741  -3.809   1.00 23.30  ? 370  PHE A CE1 1 
ATOM   2814  C CE2 . PHE A 1 377 ? -16.305 13.498  -4.555   1.00 23.94  ? 370  PHE A CE2 1 
ATOM   2815  C CZ  . PHE A 1 377 ? -15.835 14.623  -3.914   1.00 24.41  ? 370  PHE A CZ  1 
ATOM   2816  N N   . ARG A 1 378 ? -22.921 14.337  -5.588   1.00 32.02  ? 371  ARG A N   1 
ATOM   2817  C CA  . ARG A 1 378 ? -24.260 14.375  -6.226   1.00 35.59  ? 371  ARG A CA  1 
ATOM   2818  C C   . ARG A 1 378 ? -25.135 15.427  -5.525   1.00 34.98  ? 371  ARG A C   1 
ATOM   2819  O O   . ARG A 1 378 ? -25.865 16.143  -6.228   1.00 35.59  ? 371  ARG A O   1 
ATOM   2820  C CB  . ARG A 1 378 ? -24.886 12.977  -6.212   1.00 40.94  ? 371  ARG A CB  1 
ATOM   2821  C CG  . ARG A 1 378 ? -24.364 12.032  -7.290   1.00 45.42  ? 371  ARG A CG  1 
ATOM   2822  C CD  . ARG A 1 378 ? -25.403 10.948  -7.548   1.00 52.42  ? 371  ARG A CD  1 
ATOM   2823  N NE  . ARG A 1 378 ? -24.951 9.793   -8.313   1.00 57.36  ? 371  ARG A NE  1 
ATOM   2824  C CZ  . ARG A 1 378 ? -24.801 8.549   -7.838   1.00 60.17  ? 371  ARG A CZ  1 
ATOM   2825  N NH1 . ARG A 1 378 ? -25.027 8.262   -6.562   1.00 57.42  ? 371  ARG A NH1 1 
ATOM   2826  N NH2 . ARG A 1 378 ? -24.420 7.579   -8.660   1.00 60.51  ? 371  ARG A NH2 1 
ATOM   2827  N N   . GLN A 1 379 ? -25.034 15.544  -4.193   1.00 37.20  ? 372  GLN A N   1 
ATOM   2828  C CA  . GLN A 1 379 ? -25.802 16.536  -3.390   1.00 37.32  ? 372  GLN A CA  1 
ATOM   2829  C C   . GLN A 1 379 ? -25.346 17.951  -3.763   1.00 36.37  ? 372  GLN A C   1 
ATOM   2830  O O   . GLN A 1 379 ? -26.220 18.807  -4.019   1.00 38.46  ? 372  GLN A O   1 
ATOM   2831  C CB  . GLN A 1 379 ? -25.657 16.274  -1.891   1.00 39.46  ? 372  GLN A CB  1 
ATOM   2832  C CG  . GLN A 1 379 ? -26.467 17.223  -1.007   1.00 39.74  ? 372  GLN A CG  1 
ATOM   2833  C CD  . GLN A 1 379 ? -27.931 17.295  -1.385   1.00 44.11  ? 372  GLN A CD  1 
ATOM   2834  O OE1 . GLN A 1 379 ? -28.534 16.333  -1.858   1.00 43.07  ? 372  GLN A OE1 1 
ATOM   2835  N NE2 . GLN A 1 379 ? -28.529 18.456  -1.191   1.00 46.63  ? 372  GLN A NE2 1 
ATOM   2836  N N   . LEU A 1 380 ? -24.032 18.178  -3.823   1.00 35.47  ? 373  LEU A N   1 
ATOM   2837  C CA  . LEU A 1 380 ? -23.458 19.489  -4.229   1.00 34.94  ? 373  LEU A CA  1 
ATOM   2838  C C   . LEU A 1 380 ? -23.869 19.811  -5.674   1.00 33.82  ? 373  LEU A C   1 
ATOM   2839  O O   . LEU A 1 380 ? -24.024 21.005  -5.994   1.00 30.72  ? 373  LEU A O   1 
ATOM   2840  C CB  . LEU A 1 380 ? -21.937 19.448  -4.063   1.00 34.29  ? 373  LEU A CB  1 
ATOM   2841  C CG  . LEU A 1 380 ? -21.446 19.433  -2.616   1.00 35.10  ? 373  LEU A CG  1 
ATOM   2842  C CD1 . LEU A 1 380 ? -19.927 19.331  -2.565   1.00 35.91  ? 373  LEU A CD1 1 
ATOM   2843  C CD2 . LEU A 1 380 ? -21.925 20.666  -1.842   1.00 36.19  ? 373  LEU A CD2 1 
ATOM   2844  N N   . ALA A 1 381 ? -24.047 18.785  -6.509   1.00 34.14  ? 374  ALA A N   1 
ATOM   2845  C CA  . ALA A 1 381 ? -24.470 18.941  -7.916   1.00 37.66  ? 374  ALA A CA  1 
ATOM   2846  C C   . ALA A 1 381 ? -25.903 19.467  -7.932   1.00 40.27  ? 374  ALA A C   1 
ATOM   2847  O O   . ALA A 1 381 ? -26.164 20.418  -8.693   1.00 42.71  ? 374  ALA A O   1 
ATOM   2848  C CB  . ALA A 1 381 ? -24.362 17.631  -8.661   1.00 39.04  ? 374  ALA A CB  1 
ATOM   2849  N N   . ARG A 1 382 ? -26.779 18.863  -7.120   1.00 42.20  ? 375  ARG A N   1 
ATOM   2850  C CA  . ARG A 1 382 ? -28.184 19.309  -6.952   1.00 44.35  ? 375  ARG A CA  1 
ATOM   2851  C C   . ARG A 1 382 ? -28.190 20.773  -6.521   1.00 45.70  ? 375  ARG A C   1 
ATOM   2852  O O   . ARG A 1 382 ? -29.019 21.531  -7.029   1.00 49.75  ? 375  ARG A O   1 
ATOM   2853  C CB  . ARG A 1 382 ? -28.939 18.427  -5.959   1.00 48.64  ? 375  ARG A CB  1 
ATOM   2854  C CG  . ARG A 1 382 ? -29.641 17.261  -6.637   1.00 51.36  ? 375  ARG A CG  1 
ATOM   2855  C CD  . ARG A 1 382 ? -30.469 16.383  -5.724   1.00 56.94  ? 375  ARG A CD  1 
ATOM   2856  N NE  . ARG A 1 382 ? -30.042 15.005  -5.930   1.00 62.87  ? 375  ARG A NE  1 
ATOM   2857  C CZ  . ARG A 1 382 ? -29.217 14.322  -5.127   1.00 62.10  ? 375  ARG A CZ  1 
ATOM   2858  N NH1 . ARG A 1 382 ? -28.755 14.860  -4.016   1.00 57.64  ? 375  ARG A NH1 1 
ATOM   2859  N NH2 . ARG A 1 382 ? -28.863 13.081  -5.421   1.00 64.90  ? 375  ARG A NH2 1 
ATOM   2860  N N   . GLU A 1 383 ? -27.269 21.162  -5.650   1.00 46.20  ? 376  GLU A N   1 
ATOM   2861  C CA  . GLU A 1 383 ? -27.254 22.511  -5.037   1.00 48.52  ? 376  GLU A CA  1 
ATOM   2862  C C   . GLU A 1 383 ? -26.634 23.530  -6.001   1.00 47.07  ? 376  GLU A C   1 
ATOM   2863  O O   . GLU A 1 383 ? -27.004 24.712  -5.915   1.00 46.26  ? 376  GLU A O   1 
ATOM   2864  C CB  . GLU A 1 383 ? -26.512 22.435  -3.703   1.00 51.44  ? 376  GLU A CB  1 
ATOM   2865  C CG  . GLU A 1 383 ? -27.186 21.468  -2.742   1.00 53.30  ? 376  GLU A CG  1 
ATOM   2866  C CD  . GLU A 1 383 ? -26.746 21.589  -1.296   1.00 54.77  ? 376  GLU A CD  1 
ATOM   2867  O OE1 . GLU A 1 383 ? -26.401 22.716  -0.887   1.00 59.15  ? 376  GLU A OE1 1 
ATOM   2868  O OE2 . GLU A 1 383 ? -26.738 20.560  -0.581   1.00 51.48  ? 376  GLU A OE2 1 
ATOM   2869  N N   . TYR A 1 384 ? -25.729 23.104  -6.884   1.00 46.91  ? 377  TYR A N   1 
ATOM   2870  C CA  . TYR A 1 384 ? -24.955 24.013  -7.769   1.00 47.75  ? 377  TYR A CA  1 
ATOM   2871  C C   . TYR A 1 384 ? -25.054 23.541  -9.210   1.00 43.59  ? 377  TYR A C   1 
ATOM   2872  O O   . TYR A 1 384 ? -24.058 23.192  -9.825   1.00 48.97  ? 377  TYR A O   1 
ATOM   2873  C CB  . TYR A 1 384 ? -23.506 24.105  -7.286   1.00 46.79  ? 377  TYR A CB  1 
ATOM   2874  C CG  . TYR A 1 384 ? -23.327 24.756  -5.933   1.00 45.11  ? 377  TYR A CG  1 
ATOM   2875  C CD1 . TYR A 1 384 ? -23.176 26.129  -5.825   1.00 44.37  ? 377  TYR A CD1 1 
ATOM   2876  C CD2 . TYR A 1 384 ? -23.283 24.008  -4.771   1.00 42.25  ? 377  TYR A CD2 1 
ATOM   2877  C CE1 . TYR A 1 384 ? -22.970 26.743  -4.601   1.00 44.22  ? 377  TYR A CE1 1 
ATOM   2878  C CE2 . TYR A 1 384 ? -23.102 24.607  -3.537   1.00 42.25  ? 377  TYR A CE2 1 
ATOM   2879  C CZ  . TYR A 1 384 ? -22.944 25.979  -3.451   1.00 42.63  ? 377  TYR A CZ  1 
ATOM   2880  O OH  . TYR A 1 384 ? -22.763 26.583  -2.244   1.00 45.96  ? 377  TYR A OH  1 
ATOM   2881  N N   . PRO A 1 385 ? -26.264 23.530  -9.787   1.00 42.59  ? 378  PRO A N   1 
ATOM   2882  C CA  . PRO A 1 385 ? -26.452 23.183  -11.197  1.00 42.10  ? 378  PRO A CA  1 
ATOM   2883  C C   . PRO A 1 385 ? -25.973 24.281  -12.159  1.00 39.73  ? 378  PRO A C   1 
ATOM   2884  O O   . PRO A 1 385 ? -25.792 23.990  -13.325  1.00 38.36  ? 378  PRO A O   1 
ATOM   2885  C CB  . PRO A 1 385 ? -27.969 23.019  -11.321  1.00 40.91  ? 378  PRO A CB  1 
ATOM   2886  C CG  . PRO A 1 385 ? -28.500 23.967  -10.280  1.00 43.06  ? 378  PRO A CG  1 
ATOM   2887  C CD  . PRO A 1 385 ? -27.529 23.860  -9.116   1.00 43.57  ? 378  PRO A CD  1 
ATOM   2888  N N   . ASP A 1 386 ? -25.789 25.498  -11.639  1.00 38.21  ? 379  ASP A N   1 
ATOM   2889  C CA  . ASP A 1 386 ? -25.202 26.659  -12.360  1.00 38.01  ? 379  ASP A CA  1 
ATOM   2890  C C   . ASP A 1 386 ? -23.717 26.403  -12.656  1.00 41.43  ? 379  ASP A C   1 
ATOM   2891  O O   . ASP A 1 386 ? -23.171 27.041  -13.592  1.00 44.00  ? 379  ASP A O   1 
ATOM   2892  C CB  . ASP A 1 386 ? -25.378 27.947  -11.553  1.00 36.95  ? 379  ASP A CB  1 
ATOM   2893  C CG  . ASP A 1 386 ? -24.944 27.828  -10.103  1.00 40.82  ? 379  ASP A CG  1 
ATOM   2894  O OD1 . ASP A 1 386 ? -25.225 26.761  -9.471   1.00 39.63  ? 379  ASP A OD1 1 
ATOM   2895  O OD2 . ASP A 1 386 ? -24.324 28.801  -9.610   1.00 44.69  ? 379  ASP A OD2 1 
ATOM   2896  N N   . LEU A 1 387 ? -23.075 25.526  -11.873  1.00 40.24  ? 380  LEU A N   1 
ATOM   2897  C CA  . LEU A 1 387 ? -21.619 25.250  -11.934  1.00 36.64  ? 380  LEU A CA  1 
ATOM   2898  C C   . LEU A 1 387 ? -21.368 23.803  -12.340  1.00 34.06  ? 380  LEU A C   1 
ATOM   2899  O O   . LEU A 1 387 ? -20.451 23.567  -13.137  1.00 30.88  ? 380  LEU A O   1 
ATOM   2900  C CB  . LEU A 1 387 ? -21.035 25.541  -10.556  1.00 37.95  ? 380  LEU A CB  1 
ATOM   2901  C CG  . LEU A 1 387 ? -21.151 27.001  -10.125  1.00 41.29  ? 380  LEU A CG  1 
ATOM   2902  C CD1 . LEU A 1 387 ? -20.474 27.227  -8.784   1.00 44.03  ? 380  LEU A CD1 1 
ATOM   2903  C CD2 . LEU A 1 387 ? -20.555 27.943  -11.162  1.00 41.68  ? 380  LEU A CD2 1 
ATOM   2904  N N   . VAL A 1 388 ? -22.153 22.876  -11.802  1.00 31.87  ? 381  VAL A N   1 
ATOM   2905  C CA  . VAL A 1 388 ? -21.896 21.421  -11.950  1.00 32.65  ? 381  VAL A CA  1 
ATOM   2906  C C   . VAL A 1 388 ? -22.948 20.801  -12.852  1.00 31.40  ? 381  VAL A C   1 
ATOM   2907  O O   . VAL A 1 388 ? -24.130 20.983  -12.579  1.00 28.13  ? 381  VAL A O   1 
ATOM   2908  C CB  . VAL A 1 388 ? -21.898 20.742  -10.575  1.00 33.26  ? 381  VAL A CB  1 
ATOM   2909  C CG1 . VAL A 1 388 ? -21.725 19.227  -10.701  1.00 33.49  ? 381  VAL A CG1 1 
ATOM   2910  C CG2 . VAL A 1 388 ? -20.834 21.369  -9.682   1.00 33.40  ? 381  VAL A CG2 1 
ATOM   2911  N N   A GLN A 1 389 ? -22.511 20.076  -13.882  0.50 32.41  ? 382  GLN A N   1 
ATOM   2912  N N   B GLN A 1 389 ? -22.512 20.076  -13.880  0.50 31.87  ? 382  GLN A N   1 
ATOM   2913  C CA  A GLN A 1 389 ? -23.407 19.303  -14.777  0.50 34.24  ? 382  GLN A CA  1 
ATOM   2914  C CA  B GLN A 1 389 ? -23.424 19.308  -14.758  0.50 33.31  ? 382  GLN A CA  1 
ATOM   2915  C C   A GLN A 1 389 ? -23.797 18.033  -14.012  0.50 35.01  ? 382  GLN A C   1 
ATOM   2916  C C   B GLN A 1 389 ? -23.802 18.032  -14.000  0.50 34.42  ? 382  GLN A C   1 
ATOM   2917  O O   A GLN A 1 389 ? -24.997 17.836  -13.756  0.50 37.08  ? 382  GLN A O   1 
ATOM   2918  O O   B GLN A 1 389 ? -25.001 17.831  -13.736  0.50 36.37  ? 382  GLN A O   1 
ATOM   2919  C CB  A GLN A 1 389 ? -22.731 19.056  -16.135  0.50 35.56  ? 382  GLN A CB  1 
ATOM   2920  C CB  B GLN A 1 389 ? -22.795 19.060  -16.130  0.50 33.84  ? 382  GLN A CB  1 
ATOM   2921  C CG  A GLN A 1 389 ? -23.706 18.775  -17.284  0.50 35.15  ? 382  GLN A CG  1 
ATOM   2922  C CG  B GLN A 1 389 ? -23.785 18.452  -17.127  0.50 33.03  ? 382  GLN A CG  1 
ATOM   2923  C CD  A GLN A 1 389 ? -23.237 19.192  -18.669  0.50 34.85  ? 382  GLN A CD  1 
ATOM   2924  C CD  B GLN A 1 389 ? -24.967 19.332  -17.474  0.50 31.93  ? 382  GLN A CD  1 
ATOM   2925  O OE1 A GLN A 1 389 ? -22.085 19.021  -19.060  0.50 30.76  ? 382  GLN A OE1 1 
ATOM   2926  O OE1 B GLN A 1 389 ? -24.832 20.520  -17.757  0.50 31.31  ? 382  GLN A OE1 1 
ATOM   2927  N NE2 A GLN A 1 389 ? -24.148 19.736  -19.460  0.50 34.51  ? 382  GLN A NE2 1 
ATOM   2928  N NE2 B GLN A 1 389 ? -26.152 18.741  -17.486  0.50 30.74  ? 382  GLN A NE2 1 
ATOM   2929  N N   . GLU A 1 390 ? -22.816 17.233  -13.595  1.00 34.09  ? 383  GLU A N   1 
ATOM   2930  C CA  . GLU A 1 390 ? -23.095 15.924  -12.949  1.00 35.45  ? 383  GLU A CA  1 
ATOM   2931  C C   . GLU A 1 390 ? -21.863 15.434  -12.180  1.00 35.94  ? 383  GLU A C   1 
ATOM   2932  O O   . GLU A 1 390 ? -20.757 15.914  -12.462  1.00 40.80  ? 383  GLU A O   1 
ATOM   2933  C CB  . GLU A 1 390 ? -23.633 14.998  -14.046  1.00 36.51  ? 383  GLU A CB  1 
ATOM   2934  C CG  . GLU A 1 390 ? -22.976 13.642  -14.115  1.00 38.29  ? 383  GLU A CG  1 
ATOM   2935  C CD  . GLU A 1 390 ? -23.434 12.764  -15.264  1.00 41.46  ? 383  GLU A CD  1 
ATOM   2936  O OE1 . GLU A 1 390 ? -23.299 13.212  -16.435  1.00 42.55  ? 383  GLU A OE1 1 
ATOM   2937  O OE2 . GLU A 1 390 ? -23.846 11.613  -14.996  1.00 43.77  ? 383  GLU A OE2 1 
ATOM   2938  N N   . ALA A 1 391 ? -22.065 14.535  -11.213  1.00 34.16  ? 384  ALA A N   1 
ATOM   2939  C CA  . ALA A 1 391 ? -20.992 13.745  -10.566  1.00 33.71  ? 384  ALA A CA  1 
ATOM   2940  C C   . ALA A 1 391 ? -21.241 12.260  -10.851  1.00 31.40  ? 384  ALA A C   1 
ATOM   2941  O O   . ALA A 1 391 ? -22.418 11.824  -10.741  1.00 26.40  ? 384  ALA A O   1 
ATOM   2942  C CB  . ALA A 1 391 ? -20.948 14.035  -9.086   1.00 35.90  ? 384  ALA A CB  1 
ATOM   2943  N N   . ARG A 1 392 ? -20.181 11.532  -11.219  1.00 28.50  ? 385  ARG A N   1 
ATOM   2944  C CA  . ARG A 1 392 ? -20.218 10.079  -11.509  1.00 27.97  ? 385  ARG A CA  1 
ATOM   2945  C C   . ARG A 1 392 ? -19.123 9.392   -10.715  1.00 25.93  ? 385  ARG A C   1 
ATOM   2946  O O   . ARG A 1 392 ? -18.166 10.081  -10.308  1.00 24.90  ? 385  ARG A O   1 
ATOM   2947  C CB  . ARG A 1 392 ? -19.865 9.739   -12.955  1.00 31.83  ? 385  ARG A CB  1 
ATOM   2948  C CG  . ARG A 1 392 ? -20.259 10.765  -14.007  1.00 35.71  ? 385  ARG A CG  1 
ATOM   2949  C CD  . ARG A 1 392 ? -19.942 10.269  -15.428  1.00 33.89  ? 385  ARG A CD  1 
ATOM   2950  N NE  . ARG A 1 392 ? -18.850 11.006  -16.038  1.00 31.08  ? 385  ARG A NE  1 
ATOM   2951  C CZ  . ARG A 1 392 ? -18.925 12.265  -16.468  1.00 31.95  ? 385  ARG A CZ  1 
ATOM   2952  N NH1 . ARG A 1 392 ? -20.043 12.950  -16.357  1.00 31.68  ? 385  ARG A NH1 1 
ATOM   2953  N NH2 . ARG A 1 392 ? -17.871 12.861  -16.989  1.00 35.00  ? 385  ARG A NH2 1 
ATOM   2954  N N   . GLY A 1 393 ? -19.196 8.070   -10.615  1.00 24.91  ? 386  GLY A N   1 
ATOM   2955  C CA  . GLY A 1 393 ? -18.096 7.260   -10.065  1.00 24.13  ? 386  GLY A CA  1 
ATOM   2956  C C   . GLY A 1 393 ? -18.473 5.810   -9.859   1.00 24.35  ? 386  GLY A C   1 
ATOM   2957  O O   . GLY A 1 393 ? -19.618 5.428   -10.060  1.00 24.10  ? 386  GLY A O   1 
ATOM   2958  N N   . LYS A 1 394 ? -17.476 5.031   -9.495   1.00 24.87  ? 387  LYS A N   1 
ATOM   2959  C CA  . LYS A 1 394 ? -17.591 3.634   -9.040   1.00 26.32  ? 387  LYS A CA  1 
ATOM   2960  C C   . LYS A 1 394 ? -16.417 3.410   -8.089   1.00 27.73  ? 387  LYS A C   1 
ATOM   2961  O O   . LYS A 1 394 ? -15.256 3.638   -8.497   1.00 28.73  ? 387  LYS A O   1 
ATOM   2962  C CB  . LYS A 1 394 ? -17.552 2.709   -10.253  1.00 28.64  ? 387  LYS A CB  1 
ATOM   2963  C CG  . LYS A 1 394 ? -17.530 1.231   -9.934   1.00 30.53  ? 387  LYS A CG  1 
ATOM   2964  C CD  . LYS A 1 394 ? -18.954 0.778   -9.747   1.00 36.42  ? 387  LYS A CD  1 
ATOM   2965  C CE  . LYS A 1 394 ? -19.158 -0.690  -9.993   1.00 41.04  ? 387  LYS A CE  1 
ATOM   2966  N NZ  . LYS A 1 394 ? -19.149 -1.051  -11.427  1.00 42.89  ? 387  LYS A NZ  1 
ATOM   2967  N N   . GLY A 1 395 ? -16.695 3.053   -6.845   1.00 27.41  ? 388  GLY A N   1 
ATOM   2968  C CA  . GLY A 1 395 ? -15.654 3.039   -5.814   1.00 26.39  ? 388  GLY A CA  1 
ATOM   2969  C C   . GLY A 1 395 ? -14.993 4.398   -5.733   1.00 26.49  ? 388  GLY A C   1 
ATOM   2970  O O   . GLY A 1 395 ? -15.722 5.413   -5.764   1.00 22.77  ? 388  GLY A O   1 
ATOM   2971  N N   . MET A 1 396 ? -13.656 4.418   -5.682   1.00 26.06  ? 389  MET A N   1 
ATOM   2972  C CA  . MET A 1 396 ? -12.865 5.653   -5.459   1.00 24.82  ? 389  MET A CA  1 
ATOM   2973  C C   . MET A 1 396 ? -12.400 6.224   -6.793   1.00 22.56  ? 389  MET A C   1 
ATOM   2974  O O   . MET A 1 396 ? -11.482 7.040   -6.795   1.00 21.91  ? 389  MET A O   1 
ATOM   2975  C CB  . MET A 1 396 ? -11.665 5.340   -4.573   1.00 25.93  ? 389  MET A CB  1 
ATOM   2976  C CG  . MET A 1 396 ? -12.097 5.012   -3.148   1.00 28.22  ? 389  MET A CG  1 
ATOM   2977  S SD  . MET A 1 396 ? -12.769 6.449   -2.258   1.00 27.72  ? 389  MET A SD  1 
ATOM   2978  C CE  . MET A 1 396 ? -11.317 6.924   -1.311   1.00 25.17  ? 389  MET A CE  1 
ATOM   2979  N N   . LEU A 1 397 ? -13.031 5.803   -7.879   1.00 22.18  ? 390  LEU A N   1 
ATOM   2980  C CA  . LEU A 1 397 ? -12.846 6.413   -9.217   1.00 22.47  ? 390  LEU A CA  1 
ATOM   2981  C C   . LEU A 1 397 ? -14.059 7.299   -9.482   1.00 21.33  ? 390  LEU A C   1 
ATOM   2982  O O   . LEU A 1 397 ? -15.141 6.761   -9.751   1.00 20.21  ? 390  LEU A O   1 
ATOM   2983  C CB  . LEU A 1 397 ? -12.692 5.318   -10.271  1.00 22.60  ? 390  LEU A CB  1 
ATOM   2984  C CG  . LEU A 1 397 ? -12.371 5.830   -11.679  1.00 23.97  ? 390  LEU A CG  1 
ATOM   2985  C CD1 . LEU A 1 397 ? -11.092 6.676   -11.714  1.00 23.52  ? 390  LEU A CD1 1 
ATOM   2986  C CD2 . LEU A 1 397 ? -12.277 4.674   -12.665  1.00 24.50  ? 390  LEU A CD2 1 
ATOM   2987  N N   . MET A 1 398 ? -13.872 8.608   -9.358   1.00 21.28  ? 391  MET A N   1 
ATOM   2988  C CA  . MET A 1 398 ? -14.974 9.589   -9.409   1.00 21.49  ? 391  MET A CA  1 
ATOM   2989  C C   . MET A 1 398 ? -14.560 10.793  -10.243  1.00 19.41  ? 391  MET A C   1 
ATOM   2990  O O   . MET A 1 398 ? -13.349 11.044  -10.390  1.00 18.01  ? 391  MET A O   1 
ATOM   2991  C CB  . MET A 1 398 ? -15.331 10.055  -7.998   1.00 22.83  ? 391  MET A CB  1 
ATOM   2992  C CG  . MET A 1 398 ? -16.118 9.023   -7.222   1.00 24.06  ? 391  MET A CG  1 
ATOM   2993  S SD  . MET A 1 398 ? -16.178 9.380   -5.452   1.00 25.63  ? 391  MET A SD  1 
ATOM   2994  C CE  . MET A 1 398 ? -14.422 9.294   -5.074   1.00 25.01  ? 391  MET A CE  1 
ATOM   2995  N N   . ALA A 1 399 ? -15.572 11.486  -10.754  1.00 18.42  ? 392  ALA A N   1 
ATOM   2996  C CA  . ALA A 1 399 ? -15.447 12.735  -11.516  1.00 19.76  ? 392  ALA A CA  1 
ATOM   2997  C C   . ALA A 1 399 ? -16.619 13.656  -11.184  1.00 20.00  ? 392  ALA A C   1 
ATOM   2998  O O   . ALA A 1 399 ? -17.743 13.166  -10.954  1.00 19.23  ? 392  ALA A O   1 
ATOM   2999  C CB  . ALA A 1 399 ? -15.390 12.428  -12.990  1.00 19.71  ? 392  ALA A CB  1 
ATOM   3000  N N   . ILE A 1 400 ? -16.333 14.950  -11.184  1.00 22.48  ? 393  ILE A N   1 
ATOM   3001  C CA  . ILE A 1 400 ? -17.331 16.046  -11.269  1.00 25.06  ? 393  ILE A CA  1 
ATOM   3002  C C   . ILE A 1 400 ? -17.172 16.708  -12.639  1.00 28.91  ? 393  ILE A C   1 
ATOM   3003  O O   . ILE A 1 400 ? -16.094 17.269  -12.894  1.00 28.15  ? 393  ILE A O   1 
ATOM   3004  C CB  . ILE A 1 400 ? -17.114 17.051  -10.131  1.00 25.26  ? 393  ILE A CB  1 
ATOM   3005  C CG1 . ILE A 1 400 ? -17.195 16.362  -8.768   1.00 26.09  ? 393  ILE A CG1 1 
ATOM   3006  C CG2 . ILE A 1 400 ? -18.091 18.205  -10.229  1.00 25.05  ? 393  ILE A CG2 1 
ATOM   3007  C CD1 . ILE A 1 400 ? -16.539 17.150  -7.659   1.00 26.90  ? 393  ILE A CD1 1 
ATOM   3008  N N   . GLU A 1 401 ? -18.207 16.631  -13.474  1.00 33.12  ? 394  GLU A N   1 
ATOM   3009  C CA  . GLU A 1 401 ? -18.302 17.384  -14.745  1.00 36.35  ? 394  GLU A CA  1 
ATOM   3010  C C   . GLU A 1 401 ? -18.919 18.756  -14.452  1.00 36.32  ? 394  GLU A C   1 
ATOM   3011  O O   . GLU A 1 401 ? -20.045 18.805  -13.948  1.00 39.88  ? 394  GLU A O   1 
ATOM   3012  C CB  . GLU A 1 401 ? -19.123 16.598  -15.759  1.00 42.69  ? 394  GLU A CB  1 
ATOM   3013  C CG  . GLU A 1 401 ? -19.067 17.218  -17.141  1.00 49.14  ? 394  GLU A CG  1 
ATOM   3014  C CD  . GLU A 1 401 ? -19.724 16.394  -18.232  1.00 58.41  ? 394  GLU A CD  1 
ATOM   3015  O OE1 . GLU A 1 401 ? -20.554 15.519  -17.875  1.00 65.01  ? 394  GLU A OE1 1 
ATOM   3016  O OE2 . GLU A 1 401 ? -19.380 16.584  -19.421  1.00 74.39  ? 394  GLU A OE2 1 
ATOM   3017  N N   . PHE A 1 402 ? -18.205 19.832  -14.759  1.00 38.90  ? 395  PHE A N   1 
ATOM   3018  C CA  . PHE A 1 402 ? -18.700 21.223  -14.629  1.00 41.23  ? 395  PHE A CA  1 
ATOM   3019  C C   . PHE A 1 402 ? -19.357 21.638  -15.950  1.00 44.17  ? 395  PHE A C   1 
ATOM   3020  O O   . PHE A 1 402 ? -19.283 20.897  -16.953  1.00 42.50  ? 395  PHE A O   1 
ATOM   3021  C CB  . PHE A 1 402 ? -17.564 22.143  -14.184  1.00 39.35  ? 395  PHE A CB  1 
ATOM   3022  C CG  . PHE A 1 402 ? -17.051 21.738  -12.832  1.00 39.22  ? 395  PHE A CG  1 
ATOM   3023  C CD1 . PHE A 1 402 ? -16.164 20.683  -12.709  1.00 39.57  ? 395  PHE A CD1 1 
ATOM   3024  C CD2 . PHE A 1 402 ? -17.525 22.341  -11.682  1.00 38.97  ? 395  PHE A CD2 1 
ATOM   3025  C CE1 . PHE A 1 402 ? -15.730 20.267  -11.462  1.00 36.92  ? 395  PHE A CE1 1 
ATOM   3026  C CE2 . PHE A 1 402 ? -17.072 21.936  -10.439  1.00 38.03  ? 395  PHE A CE2 1 
ATOM   3027  C CZ  . PHE A 1 402 ? -16.175 20.900  -10.329  1.00 37.62  ? 395  PHE A CZ  1 
ATOM   3028  N N   . VAL A 1 403 ? -20.030 22.786  -15.922  1.00 46.05  ? 396  VAL A N   1 
ATOM   3029  C CA  . VAL A 1 403 ? -20.859 23.288  -17.054  1.00 47.51  ? 396  VAL A CA  1 
ATOM   3030  C C   . VAL A 1 403 ? -19.934 23.600  -18.234  1.00 47.53  ? 396  VAL A C   1 
ATOM   3031  O O   . VAL A 1 403 ? -20.315 23.268  -19.359  1.00 43.74  ? 396  VAL A O   1 
ATOM   3032  C CB  . VAL A 1 403 ? -21.677 24.510  -16.606  1.00 48.44  ? 396  VAL A CB  1 
ATOM   3033  C CG1 . VAL A 1 403 ? -22.213 25.297  -17.796  1.00 49.05  ? 396  VAL A CG1 1 
ATOM   3034  C CG2 . VAL A 1 403 ? -22.787 24.101  -15.656  1.00 46.01  ? 396  VAL A CG2 1 
ATOM   3035  N N   . ASP A 1 404 ? -18.768 24.202  -17.966  1.00 48.93  ? 397  ASP A N   1 
ATOM   3036  C CA  . ASP A 1 404 ? -17.759 24.586  -18.983  1.00 50.66  ? 397  ASP A CA  1 
ATOM   3037  C C   . ASP A 1 404 ? -16.351 24.425  -18.395  1.00 53.03  ? 397  ASP A C   1 
ATOM   3038  O O   . ASP A 1 404 ? -16.226 24.240  -17.152  1.00 53.51  ? 397  ASP A O   1 
ATOM   3039  C CB  . ASP A 1 404 ? -18.027 26.000  -19.498  1.00 54.90  ? 397  ASP A CB  1 
ATOM   3040  C CG  . ASP A 1 404 ? -17.708 27.121  -18.521  1.00 59.72  ? 397  ASP A CG  1 
ATOM   3041  O OD1 . ASP A 1 404 ? -16.636 27.062  -17.853  1.00 67.12  ? 397  ASP A OD1 1 
ATOM   3042  O OD2 . ASP A 1 404 ? -18.534 28.051  -18.441  1.00 67.90  ? 397  ASP A OD2 1 
ATOM   3043  N N   . ASN A 1 405 ? -15.332 24.501  -19.254  1.00 52.57  ? 398  ASN A N   1 
ATOM   3044  C CA  . ASN A 1 405 ? -13.929 24.154  -18.902  1.00 59.40  ? 398  ASN A CA  1 
ATOM   3045  C C   . ASN A 1 405 ? -13.412 25.112  -17.829  1.00 53.99  ? 398  ASN A C   1 
ATOM   3046  O O   . ASN A 1 405 ? -12.804 24.612  -16.864  1.00 44.71  ? 398  ASN A O   1 
ATOM   3047  C CB  . ASN A 1 405 ? -13.007 24.121  -20.121  1.00 62.88  ? 398  ASN A CB  1 
ATOM   3048  C CG  . ASN A 1 405 ? -13.529 23.241  -21.239  1.00 71.23  ? 398  ASN A CG  1 
ATOM   3049  O OD1 . ASN A 1 405 ? -14.707 22.878  -21.256  1.00 74.30  ? 398  ASN A OD1 1 
ATOM   3050  N ND2 . ASN A 1 405 ? -12.685 22.955  -22.213  1.00 76.35  ? 398  ASN A ND2 1 
ATOM   3051  N N   . GLU A 1 406 ? -13.656 26.417  -17.993  1.00 58.61  ? 399  GLU A N   1 
ATOM   3052  C CA  . GLU A 1 406 ? -13.079 27.483  -17.130  1.00 67.69  ? 399  GLU A CA  1 
ATOM   3053  C C   . GLU A 1 406 ? -13.584 27.327  -15.689  1.00 63.25  ? 399  GLU A C   1 
ATOM   3054  O O   . GLU A 1 406 ? -12.815 27.656  -14.760  1.00 61.15  ? 399  GLU A O   1 
ATOM   3055  C CB  . GLU A 1 406 ? -13.412 28.880  -17.650  1.00 80.58  ? 399  GLU A CB  1 
ATOM   3056  C CG  . GLU A 1 406 ? -12.738 29.969  -16.826  1.00 91.88  ? 399  GLU A CG  1 
ATOM   3057  C CD  . GLU A 1 406 ? -12.653 31.336  -17.468  1.00 101.75 ? 399  GLU A CD  1 
ATOM   3058  O OE1 . GLU A 1 406 ? -12.375 31.387  -18.679  1.00 106.37 ? 399  GLU A OE1 1 
ATOM   3059  O OE2 . GLU A 1 406 ? -12.854 32.349  -16.748  1.00 106.13 ? 399  GLU A OE2 1 
ATOM   3060  N N   . ILE A 1 407 ? -14.823 26.857  -15.514  1.00 59.30  ? 400  ILE A N   1 
ATOM   3061  C CA  . ILE A 1 407 ? -15.429 26.577  -14.177  1.00 53.94  ? 400  ILE A CA  1 
ATOM   3062  C C   . ILE A 1 407 ? -14.677 25.410  -13.511  1.00 51.87  ? 400  ILE A C   1 
ATOM   3063  O O   . ILE A 1 407 ? -14.331 25.556  -12.314  1.00 49.75  ? 400  ILE A O   1 
ATOM   3064  C CB  . ILE A 1 407 ? -16.941 26.307  -14.311  1.00 55.16  ? 400  ILE A CB  1 
ATOM   3065  C CG1 . ILE A 1 407 ? -17.715 27.571  -14.699  1.00 58.96  ? 400  ILE A CG1 1 
ATOM   3066  C CG2 . ILE A 1 407 ? -17.497 25.685  -13.046  1.00 52.34  ? 400  ILE A CG2 1 
ATOM   3067  C CD1 . ILE A 1 407 ? -19.143 27.310  -15.137  1.00 61.78  ? 400  ILE A CD1 1 
ATOM   3068  N N   . GLY A 1 408 ? -14.422 24.313  -14.247  1.00 48.85  ? 401  GLY A N   1 
ATOM   3069  C CA  . GLY A 1 408 ? -13.615 23.158  -13.794  1.00 49.27  ? 401  GLY A CA  1 
ATOM   3070  C C   . GLY A 1 408 ? -12.259 23.602  -13.255  1.00 51.24  ? 401  GLY A C   1 
ATOM   3071  O O   . GLY A 1 408 ? -11.838 23.098  -12.200  1.00 53.19  ? 401  GLY A O   1 
ATOM   3072  N N   . TYR A 1 409 ? -11.606 24.542  -13.935  1.00 54.71  ? 402  TYR A N   1 
ATOM   3073  C CA  . TYR A 1 409 ? -10.273 25.084  -13.562  1.00 58.74  ? 402  TYR A CA  1 
ATOM   3074  C C   . TYR A 1 409 ? -10.414 25.919  -12.285  1.00 51.37  ? 402  TYR A C   1 
ATOM   3075  O O   . TYR A 1 409 ? -9.526  25.844  -11.427  1.00 48.66  ? 402  TYR A O   1 
ATOM   3076  C CB  . TYR A 1 409 ? -9.643  25.921  -14.687  1.00 68.15  ? 402  TYR A CB  1 
ATOM   3077  C CG  . TYR A 1 409 ? -9.488  25.236  -16.027  1.00 80.31  ? 402  TYR A CG  1 
ATOM   3078  C CD1 . TYR A 1 409 ? -9.232  23.871  -16.125  1.00 86.23  ? 402  TYR A CD1 1 
ATOM   3079  C CD2 . TYR A 1 409 ? -9.592  25.954  -17.215  1.00 88.72  ? 402  TYR A CD2 1 
ATOM   3080  C CE1 . TYR A 1 409 ? -9.092  23.243  -17.354  1.00 92.71  ? 402  TYR A CE1 1 
ATOM   3081  C CE2 . TYR A 1 409 ? -9.454  25.341  -18.453  1.00 88.76  ? 402  TYR A CE2 1 
ATOM   3082  C CZ  . TYR A 1 409 ? -9.201  23.980  -18.522  1.00 93.24  ? 402  TYR A CZ  1 
ATOM   3083  O OH  . TYR A 1 409 ? -9.062  23.352  -19.725  1.00 90.16  ? 402  TYR A OH  1 
ATOM   3084  N N   . ASN A 1 410 ? -11.497 26.685  -12.163  1.00 46.66  ? 403  ASN A N   1 
ATOM   3085  C CA  . ASN A 1 410 ? -11.726 27.542  -10.968  1.00 48.78  ? 403  ASN A CA  1 
ATOM   3086  C C   . ASN A 1 410 ? -11.908 26.660  -9.729   1.00 43.15  ? 403  ASN A C   1 
ATOM   3087  O O   . ASN A 1 410 ? -11.452 27.064  -8.651   1.00 39.05  ? 403  ASN A O   1 
ATOM   3088  C CB  . ASN A 1 410 ? -12.905 28.487  -11.159  1.00 53.10  ? 403  ASN A CB  1 
ATOM   3089  C CG  . ASN A 1 410 ? -12.558 29.589  -12.131  1.00 60.85  ? 403  ASN A CG  1 
ATOM   3090  O OD1 . ASN A 1 410 ? -11.442 30.108  -12.113  1.00 68.34  ? 403  ASN A OD1 1 
ATOM   3091  N ND2 . ASN A 1 410 ? -13.490 29.922  -13.009  1.00 67.01  ? 403  ASN A ND2 1 
ATOM   3092  N N   . PHE A 1 411 ? -12.518 25.488  -9.903   1.00 38.54  ? 404  PHE A N   1 
ATOM   3093  C CA  . PHE A 1 411 ? -12.762 24.494  -8.831   1.00 34.61  ? 404  PHE A CA  1 
ATOM   3094  C C   . PHE A 1 411 ? -11.438 23.885  -8.376   1.00 33.02  ? 404  PHE A C   1 
ATOM   3095  O O   . PHE A 1 411 ? -11.177 23.871  -7.175   1.00 31.46  ? 404  PHE A O   1 
ATOM   3096  C CB  . PHE A 1 411 ? -13.698 23.392  -9.314   1.00 33.95  ? 404  PHE A CB  1 
ATOM   3097  C CG  . PHE A 1 411 ? -14.005 22.352  -8.273   1.00 35.70  ? 404  PHE A CG  1 
ATOM   3098  C CD1 . PHE A 1 411 ? -14.937 22.603  -7.275   1.00 36.05  ? 404  PHE A CD1 1 
ATOM   3099  C CD2 . PHE A 1 411 ? -13.366 21.125  -8.294   1.00 34.73  ? 404  PHE A CD2 1 
ATOM   3100  C CE1 . PHE A 1 411 ? -15.229 21.642  -6.321   1.00 35.00  ? 404  PHE A CE1 1 
ATOM   3101  C CE2 . PHE A 1 411 ? -13.673 20.158  -7.350   1.00 35.91  ? 404  PHE A CE2 1 
ATOM   3102  C CZ  . PHE A 1 411 ? -14.599 20.421  -6.360   1.00 34.90  ? 404  PHE A CZ  1 
ATOM   3103  N N   . ALA A 1 412 ? -10.632 23.383  -9.313   1.00 33.61  ? 405  ALA A N   1 
ATOM   3104  C CA  . ALA A 1 412 ? -9.286  22.836  -9.028   1.00 32.04  ? 405  ALA A CA  1 
ATOM   3105  C C   . ALA A 1 412 ? -8.497  23.851  -8.189   1.00 33.30  ? 405  ALA A C   1 
ATOM   3106  O O   . ALA A 1 412 ? -7.888  23.401  -7.203   1.00 32.04  ? 405  ALA A O   1 
ATOM   3107  C CB  . ALA A 1 412 ? -8.573  22.482  -10.305  1.00 32.59  ? 405  ALA A CB  1 
ATOM   3108  N N   . SER A 1 413 ? -8.546  25.149  -8.540   1.00 36.71  ? 406  SER A N   1 
ATOM   3109  C CA  . SER A 1 413 ? -7.807  26.254  -7.861   1.00 41.45  ? 406  SER A CA  1 
ATOM   3110  C C   . SER A 1 413 ? -8.358  26.458  -6.459   1.00 40.96  ? 406  SER A C   1 
ATOM   3111  O O   . SER A 1 413 ? -7.562  26.537  -5.541   1.00 44.00  ? 406  SER A O   1 
ATOM   3112  C CB  . SER A 1 413 ? -7.866  27.571  -8.582   1.00 42.92  ? 406  SER A CB  1 
ATOM   3113  O OG  . SER A 1 413 ? -7.773  27.377  -9.974   1.00 58.41  ? 406  SER A OG  1 
ATOM   3114  N N   . GLU A 1 414 ? -9.672  26.593  -6.343   1.00 42.33  ? 407  GLU A N   1 
ATOM   3115  C CA  . GLU A 1 414 ? -10.367 26.806  -5.047   1.00 46.58  ? 407  GLU A CA  1 
ATOM   3116  C C   . GLU A 1 414 ? -10.020 25.658  -4.095   1.00 42.61  ? 407  GLU A C   1 
ATOM   3117  O O   . GLU A 1 414 ? -9.647  25.953  -2.946   1.00 44.86  ? 407  GLU A O   1 
ATOM   3118  C CB  . GLU A 1 414 ? -11.870 26.996  -5.265   1.00 47.46  ? 407  GLU A CB  1 
ATOM   3119  C CG  . GLU A 1 414 ? -12.236 28.446  -5.560   1.00 52.40  ? 407  GLU A CG  1 
ATOM   3120  C CD  . GLU A 1 414 ? -11.738 29.428  -4.506   1.00 66.69  ? 407  GLU A CD  1 
ATOM   3121  O OE1 . GLU A 1 414 ? -11.807 29.077  -3.293   1.00 77.52  ? 407  GLU A OE1 1 
ATOM   3122  O OE2 . GLU A 1 414 ? -11.218 30.516  -4.887   1.00 77.03  ? 407  GLU A OE2 1 
ATOM   3123  N N   . MET A 1 415 ? -10.069 24.415  -4.576   1.00 38.64  ? 408  MET A N   1 
ATOM   3124  C CA  . MET A 1 415 ? -9.699  23.211  -3.781   1.00 37.49  ? 408  MET A CA  1 
ATOM   3125  C C   . MET A 1 415 ? -8.232  23.292  -3.345   1.00 40.08  ? 408  MET A C   1 
ATOM   3126  O O   . MET A 1 415 ? -7.936  23.002  -2.178   1.00 45.81  ? 408  MET A O   1 
ATOM   3127  C CB  . MET A 1 415 ? -9.921  21.932  -4.586   1.00 34.29  ? 408  MET A CB  1 
ATOM   3128  C CG  . MET A 1 415 ? -11.383 21.617  -4.775   1.00 34.86  ? 408  MET A CG  1 
ATOM   3129  S SD  . MET A 1 415 ? -12.269 21.326  -3.202   1.00 32.31  ? 408  MET A SD  1 
ATOM   3130  C CE  . MET A 1 415 ? -12.137 19.542  -3.124   1.00 31.65  ? 408  MET A CE  1 
ATOM   3131  N N   . PHE A 1 416 ? -7.339  23.672  -4.249   1.00 44.77  ? 409  PHE A N   1 
ATOM   3132  C CA  . PHE A 1 416 ? -5.888  23.820  -3.970   1.00 47.20  ? 409  PHE A CA  1 
ATOM   3133  C C   . PHE A 1 416 ? -5.690  24.917  -2.918   1.00 45.63  ? 409  PHE A C   1 
ATOM   3134  O O   . PHE A 1 416 ? -4.844  24.728  -2.026   1.00 44.62  ? 409  PHE A O   1 
ATOM   3135  C CB  . PHE A 1 416 ? -5.134  24.116  -5.268   1.00 49.78  ? 409  PHE A CB  1 
ATOM   3136  C CG  . PHE A 1 416 ? -3.638  23.990  -5.168   1.00 50.68  ? 409  PHE A CG  1 
ATOM   3137  C CD1 . PHE A 1 416 ? -3.014  22.780  -5.418   1.00 50.86  ? 409  PHE A CD1 1 
ATOM   3138  C CD2 . PHE A 1 416 ? -2.855  25.082  -4.841   1.00 52.02  ? 409  PHE A CD2 1 
ATOM   3139  C CE1 . PHE A 1 416 ? -1.634  22.666  -5.331   1.00 52.14  ? 409  PHE A CE1 1 
ATOM   3140  C CE2 . PHE A 1 416 ? -1.473  24.968  -4.759   1.00 53.08  ? 409  PHE A CE2 1 
ATOM   3141  C CZ  . PHE A 1 416 ? -0.865  23.760  -4.997   1.00 52.34  ? 409  PHE A CZ  1 
ATOM   3142  N N   . ARG A 1 417 ? -6.451  26.014  -3.007   1.00 45.14  ? 410  ARG A N   1 
ATOM   3143  C CA  . ARG A 1 417 ? -6.377  27.134  -2.035   1.00 50.75  ? 410  ARG A CA  1 
ATOM   3144  C C   . ARG A 1 417 ? -6.681  26.566  -0.647   1.00 49.73  ? 410  ARG A C   1 
ATOM   3145  O O   . ARG A 1 417 ? -6.074  27.043  0.328    1.00 49.01  ? 410  ARG A O   1 
ATOM   3146  C CB  . ARG A 1 417 ? -7.328  28.275  -2.410   1.00 59.62  ? 410  ARG A CB  1 
ATOM   3147  C CG  . ARG A 1 417 ? -7.541  29.343  -1.338   1.00 71.84  ? 410  ARG A CG  1 
ATOM   3148  C CD  . ARG A 1 417 ? -8.499  30.451  -1.744   1.00 85.73  ? 410  ARG A CD  1 
ATOM   3149  N NE  . ARG A 1 417 ? -8.039  31.153  -2.948   1.00 102.96 ? 410  ARG A NE  1 
ATOM   3150  C CZ  . ARG A 1 417 ? -8.705  32.093  -3.619   1.00 111.59 ? 410  ARG A CZ  1 
ATOM   3151  N NH1 . ARG A 1 417 ? -9.906  32.490  -3.222   1.00 118.08 ? 410  ARG A NH1 1 
ATOM   3152  N NH2 . ARG A 1 417 ? -8.161  32.617  -4.707   1.00 110.00 ? 410  ARG A NH2 1 
ATOM   3153  N N   . GLN A 1 418 ? -7.532  25.543  -0.582   1.00 47.18  ? 411  GLN A N   1 
ATOM   3154  C CA  . GLN A 1 418 ? -7.981  24.919  0.688    1.00 45.78  ? 411  GLN A CA  1 
ATOM   3155  C C   . GLN A 1 418 ? -7.173  23.650  0.978    1.00 45.26  ? 411  GLN A C   1 
ATOM   3156  O O   . GLN A 1 418 ? -7.576  22.888  1.854    1.00 47.45  ? 411  GLN A O   1 
ATOM   3157  C CB  . GLN A 1 418 ? -9.483  24.658  0.605    1.00 47.37  ? 411  GLN A CB  1 
ATOM   3158  C CG  . GLN A 1 418 ? -10.280 25.940  0.432    1.00 48.57  ? 411  GLN A CG  1 
ATOM   3159  C CD  . GLN A 1 418 ? -11.745 25.628  0.300    1.00 50.64  ? 411  GLN A CD  1 
ATOM   3160  O OE1 . GLN A 1 418 ? -12.384 25.184  1.251    1.00 54.00  ? 411  GLN A OE1 1 
ATOM   3161  N NE2 . GLN A 1 418 ? -12.275 25.829  -0.897   1.00 49.88  ? 411  GLN A NE2 1 
ATOM   3162  N N   . ARG A 1 419 ? -6.057  23.456  0.280    1.00 46.38  ? 412  ARG A N   1 
ATOM   3163  C CA  . ARG A 1 419 ? -5.065  22.370  0.529    1.00 45.76  ? 412  ARG A CA  1 
ATOM   3164  C C   . ARG A 1 419 ? -5.750  21.012  0.329    1.00 41.08  ? 412  ARG A C   1 
ATOM   3165  O O   . ARG A 1 419 ? -5.504  20.073  1.100    1.00 36.74  ? 412  ARG A O   1 
ATOM   3166  C CB  . ARG A 1 419 ? -4.411  22.553  1.901    1.00 49.57  ? 412  ARG A CB  1 
ATOM   3167  C CG  . ARG A 1 419 ? -3.628  23.857  2.052    1.00 52.88  ? 412  ARG A CG  1 
ATOM   3168  C CD  . ARG A 1 419 ? -2.484  24.040  1.072    1.00 61.03  ? 412  ARG A CD  1 
ATOM   3169  N NE  . ARG A 1 419 ? -1.888  25.364  1.141    1.00 70.62  ? 412  ARG A NE  1 
ATOM   3170  C CZ  . ARG A 1 419 ? -1.939  26.294  0.179    1.00 74.24  ? 412  ARG A CZ  1 
ATOM   3171  N NH1 . ARG A 1 419 ? -2.555  26.089  -0.976   1.00 71.49  ? 412  ARG A NH1 1 
ATOM   3172  N NH2 . ARG A 1 419 ? -1.364  27.464  0.393    1.00 81.97  ? 412  ARG A NH2 1 
ATOM   3173  N N   . VAL A 1 420 ? -6.567  20.920  -0.720   1.00 37.68  ? 413  VAL A N   1 
ATOM   3174  C CA  . VAL A 1 420 ? -7.086  19.631  -1.250   1.00 36.40  ? 413  VAL A CA  1 
ATOM   3175  C C   . VAL A 1 420 ? -6.668  19.525  -2.712   1.00 34.54  ? 413  VAL A C   1 
ATOM   3176  O O   . VAL A 1 420 ? -6.958  20.438  -3.499   1.00 33.19  ? 413  VAL A O   1 
ATOM   3177  C CB  . VAL A 1 420 ? -8.607  19.498  -1.099   1.00 36.86  ? 413  VAL A CB  1 
ATOM   3178  C CG1 . VAL A 1 420 ? -9.084  18.165  -1.645   1.00 37.55  ? 413  VAL A CG1 1 
ATOM   3179  C CG2 . VAL A 1 420 ? -9.047  19.700  0.340    1.00 38.54  ? 413  VAL A CG2 1 
ATOM   3180  N N   . LEU A 1 421 ? -6.023  18.419  -3.042   1.00 35.71  ? 414  LEU A N   1 
ATOM   3181  C CA  . LEU A 1 421 ? -5.359  18.200  -4.344   1.00 36.85  ? 414  LEU A CA  1 
ATOM   3182  C C   . LEU A 1 421 ? -6.297  17.393  -5.237   1.00 38.89  ? 414  LEU A C   1 
ATOM   3183  O O   . LEU A 1 421 ? -6.564  16.232  -4.923   1.00 40.16  ? 414  LEU A O   1 
ATOM   3184  C CB  . LEU A 1 421 ? -4.045  17.466  -4.082   1.00 37.92  ? 414  LEU A CB  1 
ATOM   3185  C CG  . LEU A 1 421 ? -3.100  17.358  -5.267   1.00 39.46  ? 414  LEU A CG  1 
ATOM   3186  C CD1 . LEU A 1 421 ? -2.873  18.712  -5.918   1.00 41.34  ? 414  LEU A CD1 1 
ATOM   3187  C CD2 . LEU A 1 421 ? -1.781  16.743  -4.828   1.00 38.22  ? 414  LEU A CD2 1 
ATOM   3188  N N   . VAL A 1 422 ? -6.788  18.026  -6.297   1.00 40.63  ? 415  VAL A N   1 
ATOM   3189  C CA  . VAL A 1 422 ? -7.542  17.396  -7.418   1.00 39.33  ? 415  VAL A CA  1 
ATOM   3190  C C   . VAL A 1 422 ? -6.905  17.899  -8.715   1.00 40.49  ? 415  VAL A C   1 
ATOM   3191  O O   . VAL A 1 422 ? -6.124  18.870  -8.645   1.00 43.70  ? 415  VAL A O   1 
ATOM   3192  C CB  . VAL A 1 422 ? -9.026  17.781  -7.350   1.00 36.94  ? 415  VAL A CB  1 
ATOM   3193  C CG1 . VAL A 1 422 ? -9.657  17.302  -6.057   1.00 38.32  ? 415  VAL A CG1 1 
ATOM   3194  C CG2 . VAL A 1 422 ? -9.212  19.279  -7.517   1.00 35.83  ? 415  VAL A CG2 1 
ATOM   3195  N N   . ALA A 1 423 ? -7.245  17.317  -9.859   1.00 38.53  ? 416  ALA A N   1 
ATOM   3196  C CA  . ALA A 1 423 ? -6.797  17.861  -11.156  1.00 39.97  ? 416  ALA A CA  1 
ATOM   3197  C C   . ALA A 1 423 ? -7.731  17.367  -12.240  1.00 42.72  ? 416  ALA A C   1 
ATOM   3198  O O   . ALA A 1 423 ? -8.565  16.518  -11.926  1.00 44.98  ? 416  ALA A O   1 
ATOM   3199  C CB  . ALA A 1 423 ? -5.384  17.441  -11.429  1.00 42.76  ? 416  ALA A CB  1 
ATOM   3200  N N   . GLY A 1 424 ? -7.552  17.872  -13.458  1.00 44.81  ? 417  GLY A N   1 
ATOM   3201  C CA  . GLY A 1 424 ? -8.347  17.490  -14.636  1.00 48.06  ? 417  GLY A CA  1 
ATOM   3202  C C   . GLY A 1 424 ? -8.030  16.094  -15.155  1.00 52.34  ? 417  GLY A C   1 
ATOM   3203  O O   . GLY A 1 424 ? -6.974  15.529  -14.790  1.00 53.18  ? 417  GLY A O   1 
ATOM   3204  N N   . THR A 1 425 ? -8.932  15.572  -15.993  1.00 62.22  ? 418  THR A N   1 
ATOM   3205  C CA  . THR A 1 425 ? -8.792  14.331  -16.805  1.00 66.10  ? 418  THR A CA  1 
ATOM   3206  C C   . THR A 1 425 ? -8.166  14.685  -18.165  1.00 67.91  ? 418  THR A C   1 
ATOM   3207  O O   . THR A 1 425 ? -8.244  15.874  -18.575  1.00 70.32  ? 418  THR A O   1 
ATOM   3208  C CB  . THR A 1 425 ? -10.145 13.605  -16.937  1.00 65.19  ? 418  THR A CB  1 
ATOM   3209  O OG1 . THR A 1 425 ? -11.143 14.524  -17.385  1.00 61.69  ? 418  THR A OG1 1 
ATOM   3210  C CG2 . THR A 1 425 ? -10.622 12.975  -15.646  1.00 63.23  ? 418  THR A CG2 1 
ATOM   3211  N N   . LEU A 1 426 ? -7.558  13.697  -18.833  1.00 68.60  ? 419  LEU A N   1 
ATOM   3212  C CA  . LEU A 1 426 ? -6.856  13.875  -20.138  1.00 71.22  ? 419  LEU A CA  1 
ATOM   3213  C C   . LEU A 1 426 ? -7.901  13.942  -21.273  1.00 68.17  ? 419  LEU A C   1 
ATOM   3214  O O   . LEU A 1 426 ? -8.087  15.046  -21.825  1.00 68.35  ? 419  LEU A O   1 
ATOM   3215  C CB  . LEU A 1 426 ? -5.808  12.764  -20.334  1.00 69.74  ? 419  LEU A CB  1 
ATOM   3216  C CG  . LEU A 1 426 ? -4.476  12.909  -19.574  1.00 68.74  ? 419  LEU A CG  1 
ATOM   3217  C CD1 . LEU A 1 426 ? -3.593  11.672  -19.760  1.00 65.14  ? 419  LEU A CD1 1 
ATOM   3218  C CD2 . LEU A 1 426 ? -3.699  14.156  -19.982  1.00 66.35  ? 419  LEU A CD2 1 
ATOM   3219  N N   . ASN A 1 427 ? -8.626  12.853  -21.565  1.00 63.85  ? 420  ASN A N   1 
ATOM   3220  C CA  . ASN A 1 427 ? -9.538  12.765  -22.742  1.00 65.10  ? 420  ASN A CA  1 
ATOM   3221  C C   . ASN A 1 427 ? -10.905 13.385  -22.417  1.00 70.90  ? 420  ASN A C   1 
ATOM   3222  O O   . ASN A 1 427 ? -11.920 12.846  -22.913  1.00 81.36  ? 420  ASN A O   1 
ATOM   3223  C CB  . ASN A 1 427 ? -9.704  11.323  -23.235  1.00 62.19  ? 420  ASN A CB  1 
ATOM   3224  C CG  . ASN A 1 427 ? -8.381  10.648  -23.514  1.00 62.31  ? 420  ASN A CG  1 
ATOM   3225  O OD1 . ASN A 1 427 ? -7.337  11.145  -23.104  1.00 66.41  ? 420  ASN A OD1 1 
ATOM   3226  N ND2 . ASN A 1 427 ? -8.409  9.532   -24.221  1.00 64.31  ? 420  ASN A ND2 1 
ATOM   3227  N N   . ASN A 1 428 ? -10.939 14.465  -21.625  1.00 71.47  ? 421  ASN A N   1 
ATOM   3228  C CA  . ASN A 1 428 ? -12.187 15.126  -21.147  1.00 68.81  ? 421  ASN A CA  1 
ATOM   3229  C C   . ASN A 1 428 ? -11.835 16.424  -20.407  1.00 74.03  ? 421  ASN A C   1 
ATOM   3230  O O   . ASN A 1 428 ? -11.334 16.342  -19.270  1.00 82.25  ? 421  ASN A O   1 
ATOM   3231  C CB  . ASN A 1 428 ? -13.028 14.204  -20.253  1.00 64.28  ? 421  ASN A CB  1 
ATOM   3232  C CG  . ASN A 1 428 ? -14.467 14.671  -20.079  1.00 64.87  ? 421  ASN A CG  1 
ATOM   3233  O OD1 . ASN A 1 428 ? -14.807 15.826  -20.355  1.00 59.56  ? 421  ASN A OD1 1 
ATOM   3234  N ND2 . ASN A 1 428 ? -15.334 13.779  -19.623  1.00 59.24  ? 421  ASN A ND2 1 
ATOM   3235  N N   . ALA A 1 429 ? -12.105 17.580  -21.021  1.00 77.11  ? 422  ALA A N   1 
ATOM   3236  C CA  . ALA A 1 429 ? -11.950 18.924  -20.403  1.00 80.00  ? 422  ALA A CA  1 
ATOM   3237  C C   . ALA A 1 429 ? -13.093 19.145  -19.404  1.00 80.49  ? 422  ALA A C   1 
ATOM   3238  O O   . ALA A 1 429 ? -14.051 18.339  -19.430  1.00 94.80  ? 422  ALA A O   1 
ATOM   3239  C CB  . ALA A 1 429 ? -11.948 19.984  -21.477  1.00 84.70  ? 422  ALA A CB  1 
ATOM   3240  N N   . LYS A 1 430 ? -13.007 20.169  -18.539  1.00 73.07  ? 423  LYS A N   1 
ATOM   3241  C CA  . LYS A 1 430 ? -14.140 20.641  -17.671  1.00 66.10  ? 423  LYS A CA  1 
ATOM   3242  C C   . LYS A 1 430 ? -14.574 19.554  -16.673  1.00 56.42  ? 423  LYS A C   1 
ATOM   3243  O O   . LYS A 1 430 ? -15.595 19.757  -16.004  1.00 59.43  ? 423  LYS A O   1 
ATOM   3244  C CB  . LYS A 1 430 ? -15.335 21.106  -18.531  1.00 64.73  ? 423  LYS A CB  1 
ATOM   3245  C CG  . LYS A 1 430 ? -16.325 20.054  -19.019  1.00 58.31  ? 423  LYS A CG  1 
ATOM   3246  C CD  . LYS A 1 430 ? -16.971 20.380  -20.339  1.00 57.01  ? 423  LYS A CD  1 
ATOM   3247  C CE  . LYS A 1 430 ? -18.239 19.585  -20.552  1.00 59.95  ? 423  LYS A CE  1 
ATOM   3248  N NZ  . LYS A 1 430 ? -19.376 20.118  -19.759  1.00 64.27  ? 423  LYS A NZ  1 
ATOM   3249  N N   . THR A 1 431 ? -13.823 18.452  -16.580  1.00 49.33  ? 424  THR A N   1 
ATOM   3250  C CA  . THR A 1 431 ? -14.101 17.271  -15.721  1.00 41.35  ? 424  THR A CA  1 
ATOM   3251  C C   . THR A 1 431 ? -12.926 17.118  -14.750  1.00 38.48  ? 424  THR A C   1 
ATOM   3252  O O   . THR A 1 431 ? -11.764 17.042  -15.211  1.00 31.63  ? 424  THR A O   1 
ATOM   3253  C CB  . THR A 1 431 ? -14.372 16.021  -16.567  1.00 39.41  ? 424  THR A CB  1 
ATOM   3254  O OG1 . THR A 1 431 ? -15.518 16.351  -17.337  1.00 41.84  ? 424  THR A OG1 1 
ATOM   3255  C CG2 . THR A 1 431 ? -14.667 14.769  -15.778  1.00 37.72  ? 424  THR A CG2 1 
ATOM   3256  N N   . ILE A 1 432 ? -13.230 17.106  -13.448  1.00 37.09  ? 425  ILE A N   1 
ATOM   3257  C CA  . ILE A 1 432 ? -12.225 16.973  -12.361  1.00 33.11  ? 425  ILE A CA  1 
ATOM   3258  C C   . ILE A 1 432 ? -12.325 15.557  -11.804  1.00 31.49  ? 425  ILE A C   1 
ATOM   3259  O O   . ILE A 1 432 ? -13.418 15.165  -11.409  1.00 29.94  ? 425  ILE A O   1 
ATOM   3260  C CB  . ILE A 1 432 ? -12.466 18.062  -11.313  1.00 33.34  ? 425  ILE A CB  1 
ATOM   3261  C CG1 . ILE A 1 432 ? -12.319 19.454  -11.933  1.00 34.12  ? 425  ILE A CG1 1 
ATOM   3262  C CG2 . ILE A 1 432 ? -11.557 17.873  -10.117  1.00 33.73  ? 425  ILE A CG2 1 
ATOM   3263  C CD1 . ILE A 1 432 ? -10.902 19.841  -12.261  1.00 35.56  ? 425  ILE A CD1 1 
ATOM   3264  N N   . ARG A 1 433 ? -11.217 14.818  -11.831  1.00 32.52  ? 426  ARG A N   1 
ATOM   3265  C CA  . ARG A 1 433 ? -11.104 13.461  -11.240  1.00 34.98  ? 426  ARG A CA  1 
ATOM   3266  C C   . ARG A 1 433 ? -10.981 13.604  -9.720   1.00 31.23  ? 426  ARG A C   1 
ATOM   3267  O O   . ARG A 1 433 ? -10.270 14.492  -9.240   1.00 27.72  ? 426  ARG A O   1 
ATOM   3268  C CB  . ARG A 1 433 ? -9.915  12.677  -11.823  1.00 41.53  ? 426  ARG A CB  1 
ATOM   3269  C CG  . ARG A 1 433 ? -8.534  13.174  -11.386  1.00 45.95  ? 426  ARG A CG  1 
ATOM   3270  C CD  . ARG A 1 433 ? -7.351  12.532  -12.104  1.00 52.07  ? 426  ARG A CD  1 
ATOM   3271  N NE  . ARG A 1 433 ? -7.650  12.262  -13.511  1.00 63.17  ? 426  ARG A NE  1 
ATOM   3272  C CZ  . ARG A 1 433 ? -7.348  11.153  -14.186  1.00 62.88  ? 426  ARG A CZ  1 
ATOM   3273  N NH1 . ARG A 1 433 ? -6.702  10.158  -13.610  1.00 63.57  ? 426  ARG A NH1 1 
ATOM   3274  N NH2 . ARG A 1 433 ? -7.714  11.022  -15.446  1.00 65.81  ? 426  ARG A NH2 1 
ATOM   3275  N N   . ILE A 1 434 ? -11.685 12.751  -8.994   1.00 31.49  ? 427  ILE A N   1 
ATOM   3276  C CA  . ILE A 1 434 ? -11.475 12.546  -7.542   1.00 31.02  ? 427  ILE A CA  1 
ATOM   3277  C C   . ILE A 1 434 ? -11.033 11.099  -7.398   1.00 29.35  ? 427  ILE A C   1 
ATOM   3278  O O   . ILE A 1 434 ? -11.869 10.196  -7.593   1.00 27.72  ? 427  ILE A O   1 
ATOM   3279  C CB  . ILE A 1 434 ? -12.753 12.857  -6.752   1.00 34.44  ? 427  ILE A CB  1 
ATOM   3280  C CG1 . ILE A 1 434 ? -13.341 14.226  -7.112   1.00 34.88  ? 427  ILE A CG1 1 
ATOM   3281  C CG2 . ILE A 1 434 ? -12.481 12.728  -5.259   1.00 34.07  ? 427  ILE A CG2 1 
ATOM   3282  C CD1 . ILE A 1 434 ? -12.499 15.400  -6.639   1.00 36.39  ? 427  ILE A CD1 1 
ATOM   3283  N N   . GLU A 1 435 ? -9.744  10.914  -7.127   1.00 29.04  ? 428  GLU A N   1 
ATOM   3284  C CA  . GLU A 1 435 ? -9.060  9.598   -7.101   1.00 28.93  ? 428  GLU A CA  1 
ATOM   3285  C C   . GLU A 1 435 ? -8.186  9.533   -5.853   1.00 25.70  ? 428  GLU A C   1 
ATOM   3286  O O   . GLU A 1 435 ? -6.959  9.434   -5.951   1.00 25.25  ? 428  GLU A O   1 
ATOM   3287  C CB  . GLU A 1 435 ? -8.212  9.418   -8.367   1.00 29.26  ? 428  GLU A CB  1 
ATOM   3288  C CG  . GLU A 1 435 ? -8.911  8.691   -9.477   1.00 32.57  ? 428  GLU A CG  1 
ATOM   3289  C CD  . GLU A 1 435 ? -7.995  8.331   -10.651  1.00 35.72  ? 428  GLU A CD  1 
ATOM   3290  O OE1 . GLU A 1 435 ? -7.282  7.299   -10.587  1.00 35.51  ? 428  GLU A OE1 1 
ATOM   3291  O OE2 . GLU A 1 435 ? -7.990  9.079   -11.637  1.00 38.08  ? 428  GLU A OE2 1 
ATOM   3292  N N   . PRO A 1 436 ? -8.770  9.596   -4.637   1.00 23.88  ? 429  PRO A N   1 
ATOM   3293  C CA  . PRO A 1 436 ? -7.970  9.604   -3.421   1.00 21.78  ? 429  PRO A CA  1 
ATOM   3294  C C   . PRO A 1 436 ? -7.403  8.220   -3.137   1.00 20.37  ? 429  PRO A C   1 
ATOM   3295  O O   . PRO A 1 436 ? -7.890  7.221   -3.656   1.00 20.09  ? 429  PRO A O   1 
ATOM   3296  C CB  . PRO A 1 436 ? -8.951  10.019  -2.310   1.00 21.82  ? 429  PRO A CB  1 
ATOM   3297  C CG  . PRO A 1 436 ? -10.253 10.345  -3.011   1.00 22.59  ? 429  PRO A CG  1 
ATOM   3298  C CD  . PRO A 1 436 ? -10.209 9.628   -4.341   1.00 23.69  ? 429  PRO A CD  1 
ATOM   3299  N N   . PRO A 1 437 ? -6.365  8.113   -2.289   1.00 19.45  ? 430  PRO A N   1 
ATOM   3300  C CA  . PRO A 1 437 ? -5.945  6.823   -1.754   1.00 19.51  ? 430  PRO A CA  1 
ATOM   3301  C C   . PRO A 1 437 ? -7.134  6.060   -1.180   1.00 19.61  ? 430  PRO A C   1 
ATOM   3302  O O   . PRO A 1 437 ? -7.949  6.701   -0.582   1.00 21.15  ? 430  PRO A O   1 
ATOM   3303  C CB  . PRO A 1 437 ? -4.979  7.207   -0.626   1.00 18.71  ? 430  PRO A CB  1 
ATOM   3304  C CG  . PRO A 1 437 ? -4.415  8.544   -1.066   1.00 19.35  ? 430  PRO A CG  1 
ATOM   3305  C CD  . PRO A 1 437 ? -5.547  9.230   -1.801   1.00 19.59  ? 430  PRO A CD  1 
ATOM   3306  N N   . LEU A 1 438 ? -7.183  4.740   -1.347   1.00 20.71  ? 431  LEU A N   1 
ATOM   3307  C CA  . LEU A 1 438 ? -8.258  3.889   -0.767   1.00 22.33  ? 431  LEU A CA  1 
ATOM   3308  C C   . LEU A 1 438 ? -8.208  4.028   0.760    1.00 22.82  ? 431  LEU A C   1 
ATOM   3309  O O   . LEU A 1 438 ? -9.226  3.758   1.403    1.00 29.51  ? 431  LEU A O   1 
ATOM   3310  C CB  . LEU A 1 438 ? -8.093  2.429   -1.207   1.00 22.48  ? 431  LEU A CB  1 
ATOM   3311  C CG  . LEU A 1 438 ? -7.905  2.209   -2.707   1.00 24.07  ? 431  LEU A CG  1 
ATOM   3312  C CD1 . LEU A 1 438 ? -8.157  0.756   -3.079   1.00 23.30  ? 431  LEU A CD1 1 
ATOM   3313  C CD2 . LEU A 1 438 ? -8.796  3.142   -3.510   1.00 25.68  ? 431  LEU A CD2 1 
ATOM   3314  N N   . THR A 1 439 ? -7.073  4.478   1.293    1.00 20.56  ? 432  THR A N   1 
ATOM   3315  C CA  . THR A 1 439 ? -6.783  4.646   2.734    1.00 19.82  ? 432  THR A CA  1 
ATOM   3316  C C   . THR A 1 439 ? -7.302  5.991   3.252    1.00 19.96  ? 432  THR A C   1 
ATOM   3317  O O   . THR A 1 439 ? -7.170  6.231   4.458    1.00 20.78  ? 432  THR A O   1 
ATOM   3318  C CB  . THR A 1 439 ? -5.278  4.513   2.955    1.00 19.50  ? 432  THR A CB  1 
ATOM   3319  O OG1 . THR A 1 439 ? -4.627  5.448   2.093    1.00 19.07  ? 432  THR A OG1 1 
ATOM   3320  C CG2 . THR A 1 439 ? -4.777  3.117   2.664    1.00 19.84  ? 432  THR A CG2 1 
ATOM   3321  N N   . LEU A 1 440 ? -7.889  6.831   2.398    1.00 20.25  ? 433  LEU A N   1 
ATOM   3322  C CA  . LEU A 1 440 ? -8.496  8.115   2.850    1.00 21.02  ? 433  LEU A CA  1 
ATOM   3323  C C   . LEU A 1 440 ? -9.423  7.837   4.040    1.00 20.75  ? 433  LEU A C   1 
ATOM   3324  O O   . LEU A 1 440 ? -10.267 6.941   3.925    1.00 22.04  ? 433  LEU A O   1 
ATOM   3325  C CB  . LEU A 1 440 ? -9.278  8.776   1.711    1.00 19.47  ? 433  LEU A CB  1 
ATOM   3326  C CG  . LEU A 1 440 ? -9.639  10.234  1.979    1.00 19.39  ? 433  LEU A CG  1 
ATOM   3327  C CD1 . LEU A 1 440 ? -8.397  11.118  1.942    1.00 19.66  ? 433  LEU A CD1 1 
ATOM   3328  C CD2 . LEU A 1 440 ? -10.660 10.739  0.995    1.00 19.99  ? 433  LEU A CD2 1 
ATOM   3329  N N   . THR A 1 441 ? -9.270  8.564   5.139    1.00 20.23  ? 434  THR A N   1 
ATOM   3330  C CA  . THR A 1 441 ? -10.052 8.310   6.375    1.00 21.53  ? 434  THR A CA  1 
ATOM   3331  C C   . THR A 1 441 ? -11.452 8.888   6.209    1.00 21.98  ? 434  THR A C   1 
ATOM   3332  O O   . THR A 1 441 ? -11.633 9.807   5.387    1.00 26.43  ? 434  THR A O   1 
ATOM   3333  C CB  . THR A 1 441 ? -9.414  8.898   7.644    1.00 20.14  ? 434  THR A CB  1 
ATOM   3334  O OG1 . THR A 1 441 ? -9.564  10.319  7.598    1.00 19.20  ? 434  THR A OG1 1 
ATOM   3335  C CG2 . THR A 1 441 ? -7.962  8.500   7.790    1.00 19.87  ? 434  THR A CG2 1 
ATOM   3336  N N   . ILE A 1 442 ? -12.392 8.384   6.990    1.00 21.60  ? 435  ILE A N   1 
ATOM   3337  C CA  . ILE A 1 442 ? -13.798 8.855   6.935    1.00 23.45  ? 435  ILE A CA  1 
ATOM   3338  C C   . ILE A 1 442 ? -13.806 10.347  7.232    1.00 23.04  ? 435  ILE A C   1 
ATOM   3339  O O   . ILE A 1 442 ? -14.527 11.072  6.551    1.00 19.98  ? 435  ILE A O   1 
ATOM   3340  C CB  . ILE A 1 442 ? -14.667 8.064   7.915    1.00 26.42  ? 435  ILE A CB  1 
ATOM   3341  C CG1 . ILE A 1 442 ? -14.544 6.552   7.689    1.00 27.64  ? 435  ILE A CG1 1 
ATOM   3342  C CG2 . ILE A 1 442 ? -16.116 8.544   7.829    1.00 26.78  ? 435  ILE A CG2 1 
ATOM   3343  C CD1 . ILE A 1 442 ? -15.042 6.088   6.330    1.00 27.98  ? 435  ILE A CD1 1 
ATOM   3344  N N   . GLU A 1 443 ? -13.019 10.783  8.212    1.00 26.52  ? 436  GLU A N   1 
ATOM   3345  C CA  . GLU A 1 443 ? -12.913 12.223  8.559    1.00 29.07  ? 436  GLU A CA  1 
ATOM   3346  C C   . GLU A 1 443 ? -12.435 12.991  7.322    1.00 26.89  ? 436  GLU A C   1 
ATOM   3347  O O   . GLU A 1 443 ? -13.052 14.022  7.027    1.00 26.96  ? 436  GLU A O   1 
ATOM   3348  C CB  . GLU A 1 443 ? -11.966 12.484  9.737    1.00 30.66  ? 436  GLU A CB  1 
ATOM   3349  C CG  . GLU A 1 443 ? -12.493 12.029  11.087   1.00 36.68  ? 436  GLU A CG  1 
ATOM   3350  C CD  . GLU A 1 443 ? -12.240 10.598  11.535   1.00 40.41  ? 436  GLU A CD  1 
ATOM   3351  O OE1 . GLU A 1 443 ? -11.712 9.782   10.711   1.00 45.16  ? 436  GLU A OE1 1 
ATOM   3352  O OE2 . GLU A 1 443 ? -12.611 10.302  12.696   1.00 38.97  ? 436  GLU A OE2 1 
ATOM   3353  N N   . GLN A 1 444 ? -11.383 12.524  6.642    1.00 23.41  ? 437  GLN A N   1 
ATOM   3354  C CA  . GLN A 1 444 ? -10.862 13.223  5.443    1.00 24.41  ? 437  GLN A CA  1 
ATOM   3355  C C   . GLN A 1 444 ? -11.979 13.270  4.390    1.00 23.12  ? 437  GLN A C   1 
ATOM   3356  O O   . GLN A 1 444 ? -12.221 14.367  3.858    1.00 23.20  ? 437  GLN A O   1 
ATOM   3357  C CB  . GLN A 1 444 ? -9.566  12.581  4.927    1.00 24.15  ? 437  GLN A CB  1 
ATOM   3358  C CG  . GLN A 1 444 ? -8.383  12.955  5.802    1.00 24.32  ? 437  GLN A CG  1 
ATOM   3359  C CD  . GLN A 1 444 ? -7.189  12.043  5.705    1.00 23.04  ? 437  GLN A CD  1 
ATOM   3360  O OE1 . GLN A 1 444 ? -7.290  10.854  5.422    1.00 24.87  ? 437  GLN A OE1 1 
ATOM   3361  N NE2 . GLN A 1 444 ? -6.031  12.614  5.956    1.00 22.48  ? 437  GLN A NE2 1 
ATOM   3362  N N   . CYS A 1 445 ? -12.650 12.145  4.127    1.00 22.39  ? 438  CYS A N   1 
ATOM   3363  C CA  . CYS A 1 445 ? -13.798 12.084  3.188    1.00 25.74  ? 438  CYS A CA  1 
ATOM   3364  C C   . CYS A 1 445 ? -14.736 13.275  3.459    1.00 26.87  ? 438  CYS A C   1 
ATOM   3365  O O   . CYS A 1 445 ? -15.021 14.038  2.514    1.00 26.42  ? 438  CYS A O   1 
ATOM   3366  C CB  . CYS A 1 445 ? -14.575 10.776  3.305    1.00 27.14  ? 438  CYS A CB  1 
ATOM   3367  S SG  . CYS A 1 445 ? -13.685 9.304   2.721    1.00 26.52  ? 438  CYS A SG  1 
ATOM   3368  N N   . GLU A 1 446 ? -15.160 13.456  4.714    1.00 27.15  ? 439  GLU A N   1 
ATOM   3369  C CA  . GLU A 1 446 ? -16.082 14.548  5.126    1.00 26.35  ? 439  GLU A CA  1 
ATOM   3370  C C   . GLU A 1 446 ? -15.432 15.914  4.858    1.00 25.39  ? 439  GLU A C   1 
ATOM   3371  O O   . GLU A 1 446 ? -16.135 16.813  4.352    1.00 24.68  ? 439  GLU A O   1 
ATOM   3372  C CB  . GLU A 1 446 ? -16.443 14.422  6.603    1.00 27.10  ? 439  GLU A CB  1 
ATOM   3373  C CG  . GLU A 1 446 ? -17.331 13.235  6.931    1.00 28.38  ? 439  GLU A CG  1 
ATOM   3374  C CD  . GLU A 1 446 ? -17.983 13.266  8.321    1.00 28.67  ? 439  GLU A CD  1 
ATOM   3375  O OE1 . GLU A 1 446 ? -17.938 14.325  9.007    1.00 27.26  ? 439  GLU A OE1 1 
ATOM   3376  O OE2 . GLU A 1 446 ? -18.560 12.229  8.723    1.00 26.90  ? 439  GLU A OE2 1 
ATOM   3377  N N   . LEU A 1 447 ? -14.143 16.071  5.174    1.00 25.29  ? 440  LEU A N   1 
ATOM   3378  C CA  . LEU A 1 447 ? -13.403 17.346  4.972    1.00 26.97  ? 440  LEU A CA  1 
ATOM   3379  C C   . LEU A 1 447 ? -13.388 17.678  3.484    1.00 28.31  ? 440  LEU A C   1 
ATOM   3380  O O   . LEU A 1 447 ? -13.498 18.879  3.148    1.00 29.88  ? 440  LEU A O   1 
ATOM   3381  C CB  . LEU A 1 447 ? -11.964 17.226  5.482    1.00 28.66  ? 440  LEU A CB  1 
ATOM   3382  C CG  . LEU A 1 447 ? -11.801 17.045  6.986    1.00 30.29  ? 440  LEU A CG  1 
ATOM   3383  C CD1 . LEU A 1 447 ? -10.326 16.912  7.344    1.00 32.40  ? 440  LEU A CD1 1 
ATOM   3384  C CD2 . LEU A 1 447 ? -12.468 18.172  7.747    1.00 29.82  ? 440  LEU A CD2 1 
ATOM   3385  N N   . VAL A 1 448 ? -13.253 16.652  2.633    1.00 28.44  ? 441  VAL A N   1 
ATOM   3386  C CA  . VAL A 1 448 ? -13.197 16.805  1.150    1.00 27.16  ? 441  VAL A CA  1 
ATOM   3387  C C   . VAL A 1 448 ? -14.513 17.417  0.682    1.00 26.08  ? 441  VAL A C   1 
ATOM   3388  O O   . VAL A 1 448 ? -14.491 18.431  -0.025   1.00 26.30  ? 441  VAL A O   1 
ATOM   3389  C CB  . VAL A 1 448 ? -12.876 15.464  0.464    1.00 28.05  ? 441  VAL A CB  1 
ATOM   3390  C CG1 . VAL A 1 448 ? -13.100 15.531  -1.032   1.00 27.74  ? 441  VAL A CG1 1 
ATOM   3391  C CG2 . VAL A 1 448 ? -11.433 15.028  0.737    1.00 28.93  ? 441  VAL A CG2 1 
ATOM   3392  N N   . ILE A 1 449 ? -15.626 16.851  1.127    1.00 26.69  ? 442  ILE A N   1 
ATOM   3393  C CA  . ILE A 1 449 ? -16.991 17.323  0.767    1.00 26.01  ? 442  ILE A CA  1 
ATOM   3394  C C   . ILE A 1 449 ? -17.171 18.771  1.234    1.00 25.22  ? 442  ILE A C   1 
ATOM   3395  O O   . ILE A 1 449 ? -17.736 19.567  0.482    1.00 24.87  ? 442  ILE A O   1 
ATOM   3396  C CB  . ILE A 1 449 ? -18.037 16.353  1.337    1.00 26.26  ? 442  ILE A CB  1 
ATOM   3397  C CG1 . ILE A 1 449 ? -17.911 14.984  0.647    1.00 27.15  ? 442  ILE A CG1 1 
ATOM   3398  C CG2 . ILE A 1 449 ? -19.435 16.948  1.240    1.00 26.35  ? 442  ILE A CG2 1 
ATOM   3399  C CD1 . ILE A 1 449 ? -18.807 13.884  1.179    1.00 27.18  ? 442  ILE A CD1 1 
ATOM   3400  N N   . LYS A 1 450 ? -16.680 19.116  2.416    1.00 27.25  ? 443  LYS A N   1 
ATOM   3401  C CA  . LYS A 1 450 ? -16.842 20.483  2.975    1.00 29.79  ? 443  LYS A CA  1 
ATOM   3402  C C   . LYS A 1 450 ? -15.992 21.453  2.149    1.00 30.29  ? 443  LYS A C   1 
ATOM   3403  O O   . LYS A 1 450 ? -16.479 22.564  1.855    1.00 37.16  ? 443  LYS A O   1 
ATOM   3404  C CB  . LYS A 1 450 ? -16.478 20.512  4.457    1.00 31.27  ? 443  LYS A CB  1 
ATOM   3405  C CG  . LYS A 1 450 ? -17.489 19.825  5.371    1.00 31.38  ? 443  LYS A CG  1 
ATOM   3406  C CD  . LYS A 1 450 ? -16.951 19.653  6.774    1.00 33.21  ? 443  LYS A CD  1 
ATOM   3407  C CE  . LYS A 1 450 ? -17.926 18.998  7.717    1.00 34.40  ? 443  LYS A CE  1 
ATOM   3408  N NZ  . LYS A 1 450 ? -17.291 18.720  9.030    1.00 34.86  ? 443  LYS A NZ  1 
ATOM   3409  N N   . ALA A 1 451 ? -14.779 21.043  1.780    1.00 28.42  ? 444  ALA A N   1 
ATOM   3410  C CA  . ALA A 1 451 ? -13.870 21.817  0.897    1.00 29.50  ? 444  ALA A CA  1 
ATOM   3411  C C   . ALA A 1 451 ? -14.557 22.059  -0.459   1.00 31.17  ? 444  ALA A C   1 
ATOM   3412  O O   . ALA A 1 451 ? -14.517 23.200  -0.958   1.00 32.81  ? 444  ALA A O   1 
ATOM   3413  C CB  . ALA A 1 451 ? -12.558 21.090  0.717    1.00 28.30  ? 444  ALA A CB  1 
ATOM   3414  N N   . ALA A 1 452 ? -15.166 21.022  -1.033   1.00 29.24  ? 445  ALA A N   1 
ATOM   3415  C CA  . ALA A 1 452 ? -15.881 21.120  -2.315   1.00 33.34  ? 445  ALA A CA  1 
ATOM   3416  C C   . ALA A 1 452 ? -16.992 22.167  -2.174   1.00 35.92  ? 445  ALA A C   1 
ATOM   3417  O O   . ALA A 1 452 ? -17.096 23.036  -3.059   1.00 37.66  ? 445  ALA A O   1 
ATOM   3418  C CB  . ALA A 1 452 ? -16.432 19.776  -2.718   1.00 34.86  ? 445  ALA A CB  1 
ATOM   3419  N N   . ARG A 1 453 ? -17.771 22.095  -1.095   1.00 38.08  ? 446  ARG A N   1 
ATOM   3420  C CA  . ARG A 1 453 ? -18.891 23.035  -0.825   1.00 38.44  ? 446  ARG A CA  1 
ATOM   3421  C C   . ARG A 1 453 ? -18.344 24.466  -0.786   1.00 36.07  ? 446  ARG A C   1 
ATOM   3422  O O   . ARG A 1 453 ? -18.864 25.328  -1.509   1.00 36.39  ? 446  ARG A O   1 
ATOM   3423  C CB  . ARG A 1 453 ? -19.598 22.701  0.491    1.00 40.92  ? 446  ARG A CB  1 
ATOM   3424  C CG  . ARG A 1 453 ? -20.837 23.558  0.737    1.00 41.92  ? 446  ARG A CG  1 
ATOM   3425  C CD  . ARG A 1 453 ? -21.661 23.202  1.951    1.00 38.28  ? 446  ARG A CD  1 
ATOM   3426  N NE  . ARG A 1 453 ? -22.395 21.961  1.749    1.00 39.42  ? 446  ARG A NE  1 
ATOM   3427  C CZ  . ARG A 1 453 ? -23.486 21.820  0.979    1.00 44.34  ? 446  ARG A CZ  1 
ATOM   3428  N NH1 . ARG A 1 453 ? -23.968 22.841  0.278    1.00 41.27  ? 446  ARG A NH1 1 
ATOM   3429  N NH2 . ARG A 1 453 ? -24.074 20.635  0.894    1.00 46.08  ? 446  ARG A NH2 1 
ATOM   3430  N N   . LYS A 1 454 ? -17.316 24.698  0.022    1.00 35.48  ? 447  LYS A N   1 
ATOM   3431  C CA  . LYS A 1 454 ? -16.708 26.039  0.184    1.00 38.46  ? 447  LYS A CA  1 
ATOM   3432  C C   . LYS A 1 454 ? -16.242 26.537  -1.192   1.00 38.96  ? 447  LYS A C   1 
ATOM   3433  O O   . LYS A 1 454 ? -16.455 27.726  -1.499   1.00 42.94  ? 447  LYS A O   1 
ATOM   3434  C CB  . LYS A 1 454 ? -15.598 25.974  1.239    1.00 44.29  ? 447  LYS A CB  1 
ATOM   3435  C CG  . LYS A 1 454 ? -16.087 26.247  2.660    1.00 47.32  ? 447  LYS A CG  1 
ATOM   3436  C CD  . LYS A 1 454 ? -15.039 26.066  3.738    1.00 51.51  ? 447  LYS A CD  1 
ATOM   3437  C CE  . LYS A 1 454 ? -14.583 24.628  3.876    1.00 55.10  ? 447  LYS A CE  1 
ATOM   3438  N NZ  . LYS A 1 454 ? -13.289 24.525  4.594    1.00 55.32  ? 447  LYS A NZ  1 
ATOM   3439  N N   . ALA A 1 455 ? -15.669 25.650  -2.006   1.00 37.75  ? 448  ALA A N   1 
ATOM   3440  C CA  . ALA A 1 455 ? -15.121 25.983  -3.338   1.00 37.40  ? 448  ALA A CA  1 
ATOM   3441  C C   . ALA A 1 455 ? -16.245 26.464  -4.269   1.00 40.97  ? 448  ALA A C   1 
ATOM   3442  O O   . ALA A 1 455 ? -16.089 27.535  -4.900   1.00 39.19  ? 448  ALA A O   1 
ATOM   3443  C CB  . ALA A 1 455 ? -14.409 24.782  -3.898   1.00 36.80  ? 448  ALA A CB  1 
ATOM   3444  N N   . LEU A 1 456 ? -17.344 25.707  -4.344   1.00 43.25  ? 449  LEU A N   1 
ATOM   3445  C CA  . LEU A 1 456 ? -18.511 25.999  -5.223   1.00 41.96  ? 449  LEU A CA  1 
ATOM   3446  C C   . LEU A 1 456 ? -19.151 27.329  -4.820   1.00 40.87  ? 449  LEU A C   1 
ATOM   3447  O O   . LEU A 1 456 ? -19.480 28.113  -5.712   1.00 40.44  ? 449  LEU A O   1 
ATOM   3448  C CB  . LEU A 1 456 ? -19.517 24.843  -5.142   1.00 44.78  ? 449  LEU A CB  1 
ATOM   3449  C CG  . LEU A 1 456 ? -19.037 23.544  -5.791   1.00 49.47  ? 449  LEU A CG  1 
ATOM   3450  C CD1 . LEU A 1 456 ? -19.960 22.378  -5.442   1.00 48.30  ? 449  LEU A CD1 1 
ATOM   3451  C CD2 . LEU A 1 456 ? -18.910 23.701  -7.310   1.00 50.25  ? 449  LEU A CD2 1 
ATOM   3452  N N   . ALA A 1 457 ? -19.321 27.568  -3.523   1.00 45.21  ? 450  ALA A N   1 
ATOM   3453  C CA  . ALA A 1 457 ? -19.906 28.813  -2.977   1.00 50.03  ? 450  ALA A CA  1 
ATOM   3454  C C   . ALA A 1 457 ? -19.043 30.015  -3.400   1.00 51.70  ? 450  ALA A C   1 
ATOM   3455  O O   . ALA A 1 457 ? -19.618 31.025  -3.809   1.00 53.97  ? 450  ALA A O   1 
ATOM   3456  C CB  . ALA A 1 457 ? -20.036 28.712  -1.473   1.00 50.92  ? 450  ALA A CB  1 
ATOM   3457  N N   . ALA A 1 458 ? -17.715 29.911  -3.298   1.00 53.43  ? 451  ALA A N   1 
ATOM   3458  C CA  . ALA A 1 458 ? -16.758 30.977  -3.688   1.00 59.90  ? 451  ALA A CA  1 
ATOM   3459  C C   . ALA A 1 458 ? -16.829 31.219  -5.205   1.00 59.94  ? 451  ALA A C   1 
ATOM   3460  O O   . ALA A 1 458 ? -16.815 32.390  -5.626   1.00 63.61  ? 451  ALA A O   1 
ATOM   3461  C CB  . ALA A 1 458 ? -15.361 30.609  -3.259   1.00 63.68  ? 451  ALA A CB  1 
ATOM   3462  N N   . MET A 1 459 ? -16.912 30.143  -5.987   1.00 55.74  ? 452  MET A N   1 
ATOM   3463  C CA  . MET A 1 459 ? -17.053 30.195  -7.466   1.00 55.67  ? 452  MET A CA  1 
ATOM   3464  C C   . MET A 1 459 ? -18.351 30.927  -7.852   1.00 61.47  ? 452  MET A C   1 
ATOM   3465  O O   . MET A 1 459 ? -18.327 31.757  -8.813   1.00 70.52  ? 452  MET A O   1 
ATOM   3466  C CB  . MET A 1 459 ? -17.068 28.779  -8.040   1.00 53.31  ? 452  MET A CB  1 
ATOM   3467  C CG  . MET A 1 459 ? -15.696 28.133  -8.049   1.00 52.56  ? 452  MET A CG  1 
ATOM   3468  S SD  . MET A 1 459 ? -15.809 26.341  -8.161   1.00 52.55  ? 452  MET A SD  1 
ATOM   3469  C CE  . MET A 1 459 ? -16.588 26.138  -9.761   1.00 54.20  ? 452  MET A CE  1 
ATOM   3470  N N   . ARG A 1 460 ? -19.455 30.641  -7.151   1.00 63.80  ? 453  ARG A N   1 
ATOM   3471  C CA  . ARG A 1 460 ? -20.777 31.267  -7.424   1.00 61.98  ? 453  ARG A CA  1 
ATOM   3472  C C   . ARG A 1 460 ? -20.644 32.782  -7.231   1.00 66.62  ? 453  ARG A C   1 
ATOM   3473  O O   . ARG A 1 460 ? -21.090 33.519  -8.131   1.00 78.62  ? 453  ARG A O   1 
ATOM   3474  C CB  . ARG A 1 460 ? -21.868 30.666  -6.537   1.00 61.27  ? 453  ARG A CB  1 
ATOM   3475  C CG  . ARG A 1 460 ? -23.246 31.273  -6.753   1.00 60.72  ? 453  ARG A CG  1 
ATOM   3476  C CD  . ARG A 1 460 ? -24.323 30.546  -5.974   1.00 57.11  ? 453  ARG A CD  1 
ATOM   3477  N NE  . ARG A 1 460 ? -24.794 29.355  -6.672   1.00 55.22  ? 453  ARG A NE  1 
ATOM   3478  C CZ  . ARG A 1 460 ? -25.567 28.412  -6.130   1.00 55.03  ? 453  ARG A CZ  1 
ATOM   3479  N NH1 . ARG A 1 460 ? -25.941 28.502  -4.867   1.00 56.87  ? 453  ARG A NH1 1 
ATOM   3480  N NH2 . ARG A 1 460 ? -25.958 27.370  -6.844   1.00 56.23  ? 453  ARG A NH2 1 
ATOM   3481  N N   . VAL A 1 461 ? -20.021 33.212  -6.126   1.00 66.72  ? 454  VAL A N   1 
ATOM   3482  C CA  . VAL A 1 461 ? -19.755 34.646  -5.794   1.00 71.32  ? 454  VAL A CA  1 
ATOM   3483  C C   . VAL A 1 461 ? -18.983 35.289  -6.953   1.00 76.70  ? 454  VAL A C   1 
ATOM   3484  O O   . VAL A 1 461 ? -19.485 36.295  -7.471   1.00 89.23  ? 454  VAL A O   1 
ATOM   3485  C CB  . VAL A 1 461 ? -19.018 34.806  -4.446   1.00 73.63  ? 454  VAL A CB  1 
ATOM   3486  C CG1 . VAL A 1 461 ? -18.462 36.214  -4.249   1.00 74.41  ? 454  VAL A CG1 1 
ATOM   3487  C CG2 . VAL A 1 461 ? -19.909 34.423  -3.272   1.00 73.69  ? 454  VAL A CG2 1 
ATOM   3488  N N   . SER A 1 462 ? -17.853 34.703  -7.371   1.00 83.10  ? 455  SER A N   1 
ATOM   3489  C CA  . SER A 1 462 ? -17.023 35.171  -8.517   1.00 86.32  ? 455  SER A CA  1 
ATOM   3490  C C   . SER A 1 462 ? -17.938 35.490  -9.707   1.00 87.73  ? 455  SER A C   1 
ATOM   3491  O O   . SER A 1 462 ? -17.901 36.640  -10.204  1.00 93.00  ? 455  SER A O   1 
ATOM   3492  C CB  . SER A 1 462 ? -15.971 34.158  -8.911   1.00 85.23  ? 455  SER A CB  1 
ATOM   3493  O OG  . SER A 1 462 ? -15.253 33.689  -7.779   1.00 90.27  ? 455  SER A OG  1 
ATOM   3494  N N   . VAL A 1 463 ? -18.735 34.507  -10.135  1.00 85.55  ? 456  VAL A N   1 
ATOM   3495  C CA  . VAL A 1 463 ? -19.688 34.649  -11.276  1.00 87.50  ? 456  VAL A CA  1 
ATOM   3496  C C   . VAL A 1 463 ? -20.643 35.820  -10.966  1.00 99.80  ? 456  VAL A C   1 
ATOM   3497  O O   . VAL A 1 463 ? -20.535 36.885  -11.643  1.00 117.54 ? 456  VAL A O   1 
ATOM   3498  C CB  . VAL A 1 463 ? -20.432 33.331  -11.552  1.00 77.73  ? 456  VAL A CB  1 
ATOM   3499  C CG1 . VAL A 1 463 ? -21.562 33.532  -12.548  1.00 74.74  ? 456  VAL A CG1 1 
ATOM   3500  C CG2 . VAL A 1 463 ? -19.487 32.235  -12.021  1.00 71.48  ? 456  VAL A CG2 1 
ATOM   3501  N N   . GLU A 1 464 ? -21.490 35.676  -9.933   1.00 107.45 ? 457  GLU A N   1 
ATOM   3502  C CA  . GLU A 1 464 ? -22.500 36.697  -9.517   1.00 111.37 ? 457  GLU A CA  1 
ATOM   3503  C C   . GLU A 1 464 ? -21.855 38.090  -9.555   1.00 119.85 ? 457  GLU A C   1 
ATOM   3504  O O   . GLU A 1 464 ? -22.369 38.937  -10.324  1.00 137.52 ? 457  GLU A O   1 
ATOM   3505  C CB  . GLU A 1 464 ? -23.069 36.393  -8.132   1.00 113.16 ? 457  GLU A CB  1 
ATOM   3506  C CG  . GLU A 1 464 ? -23.961 35.162  -8.080   1.00 118.08 ? 457  GLU A CG  1 
ATOM   3507  C CD  . GLU A 1 464 ? -24.167 34.595  -6.679   1.00 127.32 ? 457  GLU A CD  1 
ATOM   3508  O OE1 . GLU A 1 464 ? -23.164 34.569  -5.914   1.00 131.26 ? 457  GLU A OE1 1 
ATOM   3509  O OE2 . GLU A 1 464 ? -25.295 34.137  -6.366   1.00 134.67 ? 457  GLU A OE2 1 
ATOM   3510  N N   . GLU A 1 465 ? -20.667 38.250  -8.940   1.00 121.34 ? 458  GLU A N   1 
ATOM   3511  C CA  . GLU A 1 465 ? -19.774 39.438  -9.087   1.00 123.26 ? 458  GLU A CA  1 
ATOM   3512  C C   . GLU A 1 465 ? -19.694 39.715  -10.588  1.00 130.42 ? 458  GLU A C   1 
ATOM   3513  O O   . GLU A 1 465 ? -20.747 40.071  -11.107  1.00 165.94 ? 458  GLU A O   1 
ATOM   3514  C CB  . GLU A 1 465 ? -18.403 39.186  -8.451   1.00 116.62 ? 458  GLU A CB  1 
ATOM   3515  C CG  . GLU A 1 465 ? -18.394 39.227  -6.936   1.00 109.14 ? 458  GLU A CG  1 
ATOM   3516  C CD  . GLU A 1 465 ? -17.035 38.917  -6.324   1.00 103.50 ? 458  GLU A CD  1 
ATOM   3517  O OE1 . GLU A 1 465 ? -16.208 38.251  -6.998   1.00 86.24  ? 458  GLU A OE1 1 
ATOM   3518  O OE2 . GLU A 1 465 ? -16.813 39.329  -5.171   1.00 94.20  ? 458  GLU A OE2 1 
ATOM   3519  N N   . ALA A 1 466 ? -18.604 39.403  -11.287  1.00 116.68 ? 459  ALA A N   1 
ATOM   3520  C CA  . ALA A 1 466 ? -18.448 39.619  -12.751  1.00 111.76 ? 459  ALA A CA  1 
ATOM   3521  C C   . ALA A 1 466 ? -19.551 40.554  -13.308  1.00 112.58 ? 459  ALA A C   1 
ATOM   3522  O O   . ALA A 1 466 ? -19.207 41.664  -13.711  1.00 108.38 ? 459  ALA A O   1 
ATOM   3523  C CB  . ALA A 1 466 ? -18.430 38.288  -13.440  1.00 103.78 ? 459  ALA A CB  1 
ATOM   3524  N N   . LEU A 1 467 ? -20.834 40.155  -13.245  1.00 111.95 ? 460  LEU A N   1 
ATOM   3525  C CA  . LEU A 1 467 ? -22.027 40.998  -13.573  1.00 106.77 ? 460  LEU A CA  1 
ATOM   3526  C C   . LEU A 1 467 ? -22.084 42.238  -12.668  1.00 103.33 ? 460  LEU A C   1 
ATOM   3527  O O   . LEU A 1 467 ? -21.501 43.275  -12.970  1.00 104.34 ? 460  LEU A O   1 
ATOM   3528  C CB  . LEU A 1 467 ? -23.297 40.163  -13.385  1.00 103.91 ? 460  LEU A CB  1 
ATOM   3529  C CG  . LEU A 1 467 ? -23.446 38.972  -14.327  1.00 100.02 ? 460  LEU A CG  1 
ATOM   3530  C CD1 . LEU A 1 467 ? -24.631 38.110  -13.916  1.00 96.64  ? 460  LEU A CD1 1 
ATOM   3531  C CD2 . LEU A 1 467 ? -23.584 39.444  -15.771  1.00 96.39  ? 460  LEU A CD2 1 
ATOM   3532  N N   . ALA B 1 15  ? -2.552  -21.920 -3.315   1.00 91.35  ? 8    ALA B N   1 
ATOM   3533  C CA  . ALA B 1 15  ? -2.847  -21.059 -2.125   1.00 81.69  ? 8    ALA B CA  1 
ATOM   3534  C C   . ALA B 1 15  ? -3.613  -19.800 -2.569   1.00 67.19  ? 8    ALA B C   1 
ATOM   3535  O O   . ALA B 1 15  ? -3.752  -19.550 -3.783   1.00 53.34  ? 8    ALA B O   1 
ATOM   3536  C CB  . ALA B 1 15  ? -1.558  -20.715 -1.401   1.00 80.77  ? 8    ALA B CB  1 
ATOM   3537  N N   . SER B 1 16  ? -4.116  -19.037 -1.603   1.00 58.96  ? 9    SER B N   1 
ATOM   3538  C CA  . SER B 1 16  ? -4.629  -17.665 -1.820   1.00 50.49  ? 9    SER B CA  1 
ATOM   3539  C C   . SER B 1 16  ? -3.454  -16.766 -2.244   1.00 43.00  ? 9    SER B C   1 
ATOM   3540  O O   . SER B 1 16  ? -2.272  -17.106 -1.977   1.00 38.72  ? 9    SER B O   1 
ATOM   3541  C CB  . SER B 1 16  ? -5.352  -17.152 -0.587   1.00 48.94  ? 9    SER B CB  1 
ATOM   3542  O OG  . SER B 1 16  ? -4.434  -16.768 0.425    1.00 43.57  ? 9    SER B OG  1 
ATOM   3543  N N   . ALA B 1 17  ? -3.771  -15.659 -2.903   1.00 37.69  ? 10   ALA B N   1 
ATOM   3544  C CA  . ALA B 1 17  ? -2.821  -14.572 -3.209   1.00 35.98  ? 10   ALA B CA  1 
ATOM   3545  C C   . ALA B 1 17  ? -2.223  -14.031 -1.905   1.00 32.57  ? 10   ALA B C   1 
ATOM   3546  O O   . ALA B 1 17  ? -1.022  -13.760 -1.870   1.00 33.53  ? 10   ALA B O   1 
ATOM   3547  C CB  . ALA B 1 17  ? -3.526  -13.490 -3.989   1.00 35.89  ? 10   ALA B CB  1 
ATOM   3548  N N   . LEU B 1 18  ? -3.042  -13.852 -0.874   1.00 32.02  ? 11   LEU B N   1 
ATOM   3549  C CA  . LEU B 1 18  ? -2.588  -13.278 0.420    1.00 30.94  ? 11   LEU B CA  1 
ATOM   3550  C C   . LEU B 1 18  ? -1.441  -14.125 0.972    1.00 29.54  ? 11   LEU B C   1 
ATOM   3551  O O   . LEU B 1 18  ? -0.418  -13.544 1.389    1.00 28.45  ? 11   LEU B O   1 
ATOM   3552  C CB  . LEU B 1 18  ? -3.762  -13.247 1.404    1.00 30.21  ? 11   LEU B CB  1 
ATOM   3553  C CG  . LEU B 1 18  ? -3.443  -12.618 2.758    1.00 29.58  ? 11   LEU B CG  1 
ATOM   3554  C CD1 . LEU B 1 18  ? -2.706  -11.294 2.578    1.00 31.18  ? 11   LEU B CD1 1 
ATOM   3555  C CD2 . LEU B 1 18  ? -4.706  -12.409 3.560    1.00 27.56  ? 11   LEU B CD2 1 
ATOM   3556  N N   . ALA B 1 19  ? -1.626  -15.449 0.946    1.00 30.04  ? 12   ALA B N   1 
ATOM   3557  C CA  . ALA B 1 19  ? -0.670  -16.476 1.425    1.00 31.12  ? 12   ALA B CA  1 
ATOM   3558  C C   . ALA B 1 19  ? 0.662   -16.369 0.670    1.00 30.01  ? 12   ALA B C   1 
ATOM   3559  O O   . ALA B 1 19  ? 1.713   -16.415 1.327    1.00 29.43  ? 12   ALA B O   1 
ATOM   3560  C CB  . ALA B 1 19  ? -1.279  -17.853 1.275    1.00 31.07  ? 12   ALA B CB  1 
ATOM   3561  N N   . CYS B 1 20  ? 0.614   -16.256 -0.658   1.00 30.43  ? 13   CYS B N   1 
ATOM   3562  C CA  . CYS B 1 20  ? 1.812   -16.150 -1.528   1.00 31.69  ? 13   CYS B CA  1 
ATOM   3563  C C   . CYS B 1 20  ? 2.467   -14.779 -1.331   1.00 26.85  ? 13   CYS B C   1 
ATOM   3564  O O   . CYS B 1 20  ? 3.704   -14.758 -1.244   1.00 25.59  ? 13   CYS B O   1 
ATOM   3565  C CB  . CYS B 1 20  ? 1.477   -16.406 -2.993   1.00 37.54  ? 13   CYS B CB  1 
ATOM   3566  S SG  . CYS B 1 20  ? 0.825   -18.072 -3.292   1.00 52.22  ? 13   CYS B SG  1 
ATOM   3567  N N   . SER B 1 21  ? 1.698   -13.689 -1.218   1.00 23.30  ? 14   SER B N   1 
ATOM   3568  C CA  . SER B 1 21  ? 2.264   -12.325 -1.010   1.00 23.14  ? 14   SER B CA  1 
ATOM   3569  C C   . SER B 1 21  ? 2.988   -12.269 0.351    1.00 25.51  ? 14   SER B C   1 
ATOM   3570  O O   . SER B 1 21  ? 4.018   -11.585 0.463    1.00 24.15  ? 14   SER B O   1 
ATOM   3571  C CB  . SER B 1 21  ? 1.217   -11.243 -1.150   1.00 22.35  ? 14   SER B CB  1 
ATOM   3572  O OG  . SER B 1 21  ? 0.360   -11.188 -0.026   1.00 19.70  ? 14   SER B OG  1 
ATOM   3573  N N   . ALA B 1 22  ? 2.487   -13.018 1.337    1.00 25.88  ? 15   ALA B N   1 
ATOM   3574  C CA  . ALA B 1 22  ? 3.063   -13.142 2.690    1.00 26.56  ? 15   ALA B CA  1 
ATOM   3575  C C   . ALA B 1 22  ? 4.367   -13.939 2.620    1.00 27.44  ? 15   ALA B C   1 
ATOM   3576  O O   . ALA B 1 22  ? 5.388   -13.446 3.109    1.00 29.31  ? 15   ALA B O   1 
ATOM   3577  C CB  . ALA B 1 22  ? 2.056   -13.796 3.613    1.00 26.94  ? 15   ALA B CB  1 
ATOM   3578  N N   . HIS B 1 23  ? 4.331   -15.134 2.036    1.00 28.32  ? 16   HIS B N   1 
ATOM   3579  C CA  . HIS B 1 23  ? 5.495   -16.049 1.917    1.00 29.04  ? 16   HIS B CA  1 
ATOM   3580  C C   . HIS B 1 23  ? 6.653   -15.301 1.242    1.00 28.67  ? 16   HIS B C   1 
ATOM   3581  O O   . HIS B 1 23  ? 7.836   -15.535 1.599    1.00 26.92  ? 16   HIS B O   1 
ATOM   3582  C CB  . HIS B 1 23  ? 5.077   -17.309 1.156    1.00 31.99  ? 16   HIS B CB  1 
ATOM   3583  C CG  . HIS B 1 23  ? 6.231   -18.184 0.829    1.00 35.40  ? 16   HIS B CG  1 
ATOM   3584  N ND1 . HIS B 1 23  ? 6.910   -18.893 1.797    1.00 40.70  ? 16   HIS B ND1 1 
ATOM   3585  C CD2 . HIS B 1 23  ? 6.862   -18.420 -0.337   1.00 36.57  ? 16   HIS B CD2 1 
ATOM   3586  C CE1 . HIS B 1 23  ? 7.906   -19.548 1.236    1.00 40.56  ? 16   HIS B CE1 1 
ATOM   3587  N NE2 . HIS B 1 23  ? 7.889   -19.277 -0.071   1.00 38.32  ? 16   HIS B NE2 1 
ATOM   3588  N N   . ALA B 1 24  ? 6.314   -14.413 0.308    1.00 26.45  ? 17   ALA B N   1 
ATOM   3589  C CA  . ALA B 1 24  ? 7.280   -13.665 -0.522   1.00 26.21  ? 17   ALA B CA  1 
ATOM   3590  C C   . ALA B 1 24  ? 7.852   -12.501 0.278    1.00 24.49  ? 17   ALA B C   1 
ATOM   3591  O O   . ALA B 1 24  ? 9.038   -12.265 0.160    1.00 22.92  ? 17   ALA B O   1 
ATOM   3592  C CB  . ALA B 1 24  ? 6.619   -13.181 -1.787   1.00 26.52  ? 17   ALA B CB  1 
ATOM   3593  N N   . LEU B 1 25  ? 7.033   -11.773 1.030    1.00 24.30  ? 18   LEU B N   1 
ATOM   3594  C CA  . LEU B 1 25  ? 7.561   -10.687 1.901    1.00 26.04  ? 18   LEU B CA  1 
ATOM   3595  C C   . LEU B 1 25  ? 8.519   -11.268 2.962    1.00 25.18  ? 18   LEU B C   1 
ATOM   3596  O O   . LEU B 1 25  ? 9.520   -10.603 3.292    1.00 24.45  ? 18   LEU B O   1 
ATOM   3597  C CB  . LEU B 1 25  ? 6.395   -9.936  2.543    1.00 24.61  ? 18   LEU B CB  1 
ATOM   3598  C CG  . LEU B 1 25  ? 5.549   -9.123  1.569    1.00 24.16  ? 18   LEU B CG  1 
ATOM   3599  C CD1 . LEU B 1 25  ? 4.323   -8.585  2.279    1.00 24.81  ? 18   LEU B CD1 1 
ATOM   3600  C CD2 . LEU B 1 25  ? 6.342   -7.991  0.945    1.00 23.49  ? 18   LEU B CD2 1 
ATOM   3601  N N   A ASN B 1 26  ? 8.211   -12.468 3.466    0.54 26.30  ? 19   ASN B N   1 
ATOM   3602  N N   B ASN B 1 26  ? 8.211   -12.469 3.469    0.46 24.25  ? 19   ASN B N   1 
ATOM   3603  C CA  A ASN B 1 26  ? 9.071   -13.261 4.391    0.54 26.86  ? 19   ASN B CA  1 
ATOM   3604  C CA  B ASN B 1 26  ? 9.078   -13.263 4.382    0.46 23.54  ? 19   ASN B CA  1 
ATOM   3605  C C   A ASN B 1 26  ? 10.425  -13.499 3.714    0.54 25.90  ? 19   ASN B C   1 
ATOM   3606  C C   B ASN B 1 26  ? 10.430  -13.502 3.701    0.46 23.18  ? 19   ASN B C   1 
ATOM   3607  O O   A ASN B 1 26  ? 11.464  -13.298 4.367    0.54 25.45  ? 19   ASN B O   1 
ATOM   3608  O O   B ASN B 1 26  ? 11.469  -13.301 4.357    0.46 22.88  ? 19   ASN B O   1 
ATOM   3609  C CB  A ASN B 1 26  ? 8.425   -14.596 4.779    0.54 28.36  ? 19   ASN B CB  1 
ATOM   3610  C CB  B ASN B 1 26  ? 8.461   -14.616 4.752    0.46 23.22  ? 19   ASN B CB  1 
ATOM   3611  C CG  A ASN B 1 26  ? 9.294   -15.443 5.685    0.54 30.20  ? 19   ASN B CG  1 
ATOM   3612  C CG  B ASN B 1 26  ? 7.469   -14.565 5.892    0.46 22.93  ? 19   ASN B CG  1 
ATOM   3613  O OD1 A ASN B 1 26  ? 9.502   -15.095 6.847    0.54 32.87  ? 19   ASN B OD1 1 
ATOM   3614  O OD1 B ASN B 1 26  ? 7.330   -13.550 6.569    0.46 22.68  ? 19   ASN B OD1 1 
ATOM   3615  N ND2 A ASN B 1 26  ? 9.800   -16.555 5.168    0.54 30.96  ? 19   ASN B ND2 1 
ATOM   3616  N ND2 B ASN B 1 26  ? 6.782   -15.673 6.117    0.46 23.02  ? 19   ASN B ND2 1 
ATOM   3617  N N   A LEU B 1 27  ? 10.402  -13.902 2.447    0.54 25.10  ? 20   LEU B N   1 
ATOM   3618  N N   B LEU B 1 27  ? 10.406  -13.911 2.430    0.46 22.99  ? 20   LEU B N   1 
ATOM   3619  C CA  A LEU B 1 27  ? 11.626  -14.188 1.652    0.54 25.22  ? 20   LEU B CA  1 
ATOM   3620  C CA  B LEU B 1 27  ? 11.625  -14.197 1.619    0.46 23.37  ? 20   LEU B CA  1 
ATOM   3621  C C   A LEU B 1 27  ? 12.425  -12.907 1.397    0.54 24.52  ? 20   LEU B C   1 
ATOM   3622  C C   B LEU B 1 27  ? 12.428  -12.907 1.398    0.46 23.47  ? 20   LEU B C   1 
ATOM   3623  O O   A LEU B 1 27  ? 13.661  -12.979 1.475    0.54 24.41  ? 20   LEU B O   1 
ATOM   3624  O O   B LEU B 1 27  ? 13.668  -12.978 1.469    0.46 23.41  ? 20   LEU B O   1 
ATOM   3625  C CB  A LEU B 1 27  ? 11.220  -14.898 0.365    0.54 25.58  ? 20   LEU B CB  1 
ATOM   3626  C CB  B LEU B 1 27  ? 11.225  -14.834 0.285    0.46 23.39  ? 20   LEU B CB  1 
ATOM   3627  C CG  A LEU B 1 27  ? 11.066  -16.402 0.575    0.54 26.46  ? 20   LEU B CG  1 
ATOM   3628  C CG  B LEU B 1 27  ? 12.388  -15.187 -0.637   0.46 23.80  ? 20   LEU B CG  1 
ATOM   3629  C CD1 A LEU B 1 27  ? 10.431  -17.061 -0.638   0.54 27.48  ? 20   LEU B CD1 1 
ATOM   3630  C CD1 B LEU B 1 27  ? 13.046  -16.474 -0.170   0.46 24.33  ? 20   LEU B CD1 1 
ATOM   3631  C CD2 A LEU B 1 27  ? 12.402  -17.045 0.932    0.54 26.27  ? 20   LEU B CD2 1 
ATOM   3632  C CD2 B LEU B 1 27  ? 11.927  -15.321 -2.078   0.46 23.52  ? 20   LEU B CD2 1 
ATOM   3633  N N   . ILE B 1 28  ? 11.761  -11.772 1.176    1.00 23.34  ? 21   ILE B N   1 
ATOM   3634  C CA  . ILE B 1 28  ? 12.426  -10.455 0.947    1.00 24.96  ? 21   ILE B CA  1 
ATOM   3635  C C   . ILE B 1 28  ? 13.241  -10.038 2.178    1.00 26.20  ? 21   ILE B C   1 
ATOM   3636  O O   . ILE B 1 28  ? 14.312  -9.436  1.981    1.00 25.90  ? 21   ILE B O   1 
ATOM   3637  C CB  . ILE B 1 28  ? 11.385  -9.399  0.535    1.00 25.93  ? 21   ILE B CB  1 
ATOM   3638  C CG1 . ILE B 1 28  ? 10.868  -9.704  -0.873   1.00 26.30  ? 21   ILE B CG1 1 
ATOM   3639  C CG2 . ILE B 1 28  ? 11.937  -7.986  0.638    1.00 27.31  ? 21   ILE B CG2 1 
ATOM   3640  C CD1 . ILE B 1 28  ? 9.678   -8.885  -1.295   1.00 26.03  ? 21   ILE B CD1 1 
ATOM   3641  N N   . GLU B 1 29  ? 12.761  -10.339 3.385    1.00 27.64  ? 22   GLU B N   1 
ATOM   3642  C CA  . GLU B 1 29  ? 13.441  -9.982  4.661    1.00 31.13  ? 22   GLU B CA  1 
ATOM   3643  C C   . GLU B 1 29  ? 14.681  -10.847 4.886    1.00 30.16  ? 22   GLU B C   1 
ATOM   3644  O O   . GLU B 1 29  ? 15.670  -10.294 5.364    1.00 32.08  ? 22   GLU B O   1 
ATOM   3645  C CB  . GLU B 1 29  ? 12.512  -10.171 5.854    1.00 33.63  ? 22   GLU B CB  1 
ATOM   3646  C CG  . GLU B 1 29  ? 11.308  -9.253  5.785    1.00 40.35  ? 22   GLU B CG  1 
ATOM   3647  C CD  . GLU B 1 29  ? 10.418  -9.263  7.014    1.00 44.81  ? 22   GLU B CD  1 
ATOM   3648  O OE1 . GLU B 1 29  ? 11.013  -9.211  8.144    1.00 42.18  ? 22   GLU B OE1 1 
ATOM   3649  O OE2 . GLU B 1 29  ? 9.154   -9.310  6.833    1.00 40.28  ? 22   GLU B OE2 1 
ATOM   3650  N N   . LYS B 1 30  ? 14.598  -12.148 4.595    1.00 29.95  ? 23   LYS B N   1 
ATOM   3651  C CA  . LYS B 1 30  ? 15.684  -13.148 4.771    1.00 31.56  ? 23   LYS B CA  1 
ATOM   3652  C C   . LYS B 1 30  ? 16.919  -12.665 4.007    1.00 30.86  ? 23   LYS B C   1 
ATOM   3653  O O   . LYS B 1 30  ? 16.758  -12.163 2.898    1.00 32.90  ? 23   LYS B O   1 
ATOM   3654  C CB  . LYS B 1 30  ? 15.220  -14.542 4.324    1.00 35.43  ? 23   LYS B CB  1 
ATOM   3655  C CG  . LYS B 1 30  ? 14.212  -15.190 5.282    1.00 43.06  ? 23   LYS B CG  1 
ATOM   3656  C CD  . LYS B 1 30  ? 13.626  -16.560 4.887    1.00 45.46  ? 23   LYS B CD  1 
ATOM   3657  C CE  . LYS B 1 30  ? 14.624  -17.708 4.918    1.00 48.38  ? 23   LYS B CE  1 
ATOM   3658  N NZ  . LYS B 1 30  ? 15.597  -17.634 6.048    1.00 45.56  ? 23   LYS B NZ  1 
ATOM   3659  N N   . ARG B 1 31  ? 18.100  -12.740 4.620    1.00 29.15  ? 24   ARG B N   1 
ATOM   3660  C CA  . ARG B 1 31  ? 19.409  -12.450 3.984    1.00 28.05  ? 24   ARG B CA  1 
ATOM   3661  C C   . ARG B 1 31  ? 20.173  -13.752 3.800    1.00 25.93  ? 24   ARG B C   1 
ATOM   3662  O O   . ARG B 1 31  ? 21.142  -13.735 3.018    1.00 23.90  ? 24   ARG B O   1 
ATOM   3663  C CB  . ARG B 1 31  ? 20.284  -11.534 4.839    1.00 30.40  ? 24   ARG B CB  1 
ATOM   3664  C CG  . ARG B 1 31  ? 19.735  -10.131 5.033    1.00 32.95  ? 24   ARG B CG  1 
ATOM   3665  C CD  . ARG B 1 31  ? 19.700  -9.339  3.753    1.00 37.31  ? 24   ARG B CD  1 
ATOM   3666  N NE  . ARG B 1 31  ? 19.016  -8.102  4.077    1.00 42.88  ? 24   ARG B NE  1 
ATOM   3667  C CZ  . ARG B 1 31  ? 19.584  -7.023  4.608    1.00 43.13  ? 24   ARG B CZ  1 
ATOM   3668  N NH1 . ARG B 1 31  ? 20.886  -6.988  4.855    1.00 41.55  ? 24   ARG B NH1 1 
ATOM   3669  N NH2 . ARG B 1 31  ? 18.829  -5.967  4.875    1.00 42.25  ? 24   ARG B NH2 1 
ATOM   3670  N N   . THR B 1 32  ? 19.744  -14.837 4.440    1.00 25.90  ? 25   THR B N   1 
ATOM   3671  C CA  . THR B 1 32  ? 20.452  -16.141 4.423    1.00 28.53  ? 25   THR B CA  1 
ATOM   3672  C C   . THR B 1 32  ? 19.455  -17.268 4.184    1.00 28.81  ? 25   THR B C   1 
ATOM   3673  O O   . THR B 1 32  ? 18.280  -17.076 4.513    1.00 29.13  ? 25   THR B O   1 
ATOM   3674  C CB  . THR B 1 32  ? 21.217  -16.385 5.731    1.00 31.91  ? 25   THR B CB  1 
ATOM   3675  O OG1 . THR B 1 32  ? 20.311  -16.295 6.836    1.00 29.86  ? 25   THR B OG1 1 
ATOM   3676  C CG2 . THR B 1 32  ? 22.362  -15.416 5.922    1.00 32.45  ? 25   THR B CG2 1 
ATOM   3677  N N   . LEU B 1 33  ? 19.952  -18.367 3.629    1.00 28.55  ? 26   LEU B N   1 
ATOM   3678  C CA  . LEU B 1 33  ? 19.175  -19.589 3.335    1.00 29.64  ? 26   LEU B CA  1 
ATOM   3679  C C   . LEU B 1 33  ? 20.023  -20.773 3.765    1.00 30.78  ? 26   LEU B C   1 
ATOM   3680  O O   . LEU B 1 33  ? 21.139  -20.859 3.296    1.00 34.26  ? 26   LEU B O   1 
ATOM   3681  C CB  . LEU B 1 33  ? 18.887  -19.657 1.830    1.00 27.94  ? 26   LEU B CB  1 
ATOM   3682  C CG  . LEU B 1 33  ? 18.076  -18.511 1.247    1.00 26.43  ? 26   LEU B CG  1 
ATOM   3683  C CD1 . LEU B 1 33  ? 18.178  -18.498 -0.263   1.00 27.34  ? 26   LEU B CD1 1 
ATOM   3684  C CD2 . LEU B 1 33  ? 16.619  -18.581 1.638    1.00 26.87  ? 26   LEU B CD2 1 
ATOM   3685  N N   . ASP B 1 34  ? 19.525  -21.642 4.632    1.00 36.04  ? 27   ASP B N   1 
ATOM   3686  C CA  . ASP B 1 34  ? 20.212  -22.933 4.897    1.00 40.08  ? 27   ASP B CA  1 
ATOM   3687  C C   . ASP B 1 34  ? 19.936  -23.821 3.680    1.00 37.92  ? 27   ASP B C   1 
ATOM   3688  O O   . ASP B 1 34  ? 19.116  -23.420 2.841    1.00 38.83  ? 27   ASP B O   1 
ATOM   3689  C CB  . ASP B 1 34  ? 19.841  -23.538 6.260    1.00 42.86  ? 27   ASP B CB  1 
ATOM   3690  C CG  . ASP B 1 34  ? 18.396  -23.980 6.417    1.00 42.55  ? 27   ASP B CG  1 
ATOM   3691  O OD1 . ASP B 1 34  ? 17.711  -24.136 5.390    1.00 38.96  ? 27   ASP B OD1 1 
ATOM   3692  O OD2 . ASP B 1 34  ? 17.961  -24.147 7.595    1.00 48.32  ? 27   ASP B OD2 1 
ATOM   3693  N N   . HIS B 1 35  ? 20.598  -24.970 3.590    1.00 37.54  ? 28   HIS B N   1 
ATOM   3694  C CA  . HIS B 1 35  ? 20.433  -25.946 2.487    1.00 42.69  ? 28   HIS B CA  1 
ATOM   3695  C C   . HIS B 1 35  ? 18.941  -26.198 2.218    1.00 45.00  ? 28   HIS B C   1 
ATOM   3696  O O   . HIS B 1 35  ? 18.568  -26.256 1.039    1.00 49.30  ? 28   HIS B O   1 
ATOM   3697  C CB  . HIS B 1 35  ? 21.193  -27.233 2.798    1.00 47.22  ? 28   HIS B CB  1 
ATOM   3698  C CG  . HIS B 1 35  ? 21.289  -28.144 1.624    1.00 54.53  ? 28   HIS B CG  1 
ATOM   3699  N ND1 . HIS B 1 35  ? 22.153  -27.892 0.572    1.00 61.06  ? 28   HIS B ND1 1 
ATOM   3700  C CD2 . HIS B 1 35  ? 20.630  -29.284 1.317    1.00 60.49  ? 28   HIS B CD2 1 
ATOM   3701  C CE1 . HIS B 1 35  ? 22.033  -28.844 -0.333   1.00 62.14  ? 28   HIS B CE1 1 
ATOM   3702  N NE2 . HIS B 1 35  ? 21.097  -29.706 0.097    1.00 68.37  ? 28   HIS B NE2 1 
ATOM   3703  N N   . GLU B 1 36  ? 18.113  -26.323 3.257    1.00 47.66  ? 29   GLU B N   1 
ATOM   3704  C CA  . GLU B 1 36  ? 16.674  -26.694 3.127    1.00 47.95  ? 29   GLU B CA  1 
ATOM   3705  C C   . GLU B 1 36  ? 15.863  -25.516 2.582    1.00 40.44  ? 29   GLU B C   1 
ATOM   3706  O O   . GLU B 1 36  ? 14.989  -25.765 1.730    1.00 41.26  ? 29   GLU B O   1 
ATOM   3707  C CB  . GLU B 1 36  ? 16.091  -27.194 4.457    1.00 57.35  ? 29   GLU B CB  1 
ATOM   3708  C CG  . GLU B 1 36  ? 16.507  -28.617 4.793    1.00 63.85  ? 29   GLU B CG  1 
ATOM   3709  C CD  . GLU B 1 36  ? 16.532  -29.561 3.602    1.00 69.69  ? 29   GLU B CD  1 
ATOM   3710  O OE1 . GLU B 1 36  ? 15.453  -29.769 2.999    1.00 74.10  ? 29   GLU B OE1 1 
ATOM   3711  O OE2 . GLU B 1 36  ? 17.639  -30.055 3.250    1.00 75.19  ? 29   GLU B OE2 1 
ATOM   3712  N N   . GLU B 1 37  ? 16.123  -24.294 3.051    1.00 33.65  ? 30   GLU B N   1 
ATOM   3713  C CA  . GLU B 1 37  ? 15.387  -23.091 2.596    1.00 32.99  ? 30   GLU B CA  1 
ATOM   3714  C C   . GLU B 1 37  ? 15.721  -22.852 1.127    1.00 31.57  ? 30   GLU B C   1 
ATOM   3715  O O   . GLU B 1 37  ? 14.790  -22.564 0.368    1.00 32.04  ? 30   GLU B O   1 
ATOM   3716  C CB  . GLU B 1 37  ? 15.740  -21.875 3.440    1.00 33.56  ? 30   GLU B CB  1 
ATOM   3717  C CG  . GLU B 1 37  ? 15.196  -21.948 4.847    1.00 38.37  ? 30   GLU B CG  1 
ATOM   3718  C CD  . GLU B 1 37  ? 15.834  -20.989 5.837    1.00 42.36  ? 30   GLU B CD  1 
ATOM   3719  O OE1 . GLU B 1 37  ? 17.062  -20.766 5.754    1.00 47.33  ? 30   GLU B OE1 1 
ATOM   3720  O OE2 . GLU B 1 37  ? 15.095  -20.465 6.698    1.00 48.60  ? 30   GLU B OE2 1 
ATOM   3721  N N   . MET B 1 38  ? 17.002  -22.976 0.779    1.00 30.98  ? 31   MET B N   1 
ATOM   3722  C CA  . MET B 1 38  ? 17.544  -22.848 -0.598   1.00 34.42  ? 31   MET B CA  1 
ATOM   3723  C C   . MET B 1 38  ? 16.870  -23.878 -1.505   1.00 36.20  ? 31   MET B C   1 
ATOM   3724  O O   . MET B 1 38  ? 16.377  -23.468 -2.569   1.00 36.74  ? 31   MET B O   1 
ATOM   3725  C CB  . MET B 1 38  ? 19.059  -23.079 -0.611   1.00 36.49  ? 31   MET B CB  1 
ATOM   3726  C CG  . MET B 1 38  ? 19.694  -23.057 -1.978   1.00 38.44  ? 31   MET B CG  1 
ATOM   3727  S SD  . MET B 1 38  ? 19.842  -24.681 -2.781   1.00 42.60  ? 31   MET B SD  1 
ATOM   3728  C CE  . MET B 1 38  ? 21.070  -25.449 -1.727   1.00 43.64  ? 31   MET B CE  1 
ATOM   3729  N N   . LYS B 1 39  ? 16.862  -25.157 -1.114   1.00 37.86  ? 32   LYS B N   1 
ATOM   3730  C CA  . LYS B 1 39  ? 16.336  -26.265 -1.960   1.00 40.61  ? 32   LYS B CA  1 
ATOM   3731  C C   . LYS B 1 39  ? 14.859  -26.012 -2.235   1.00 35.55  ? 32   LYS B C   1 
ATOM   3732  O O   . LYS B 1 39  ? 14.439  -26.226 -3.364   1.00 33.21  ? 32   LYS B O   1 
ATOM   3733  C CB  . LYS B 1 39  ? 16.522  -27.648 -1.324   1.00 47.97  ? 32   LYS B CB  1 
ATOM   3734  C CG  . LYS B 1 39  ? 17.517  -28.549 -2.051   1.00 57.22  ? 32   LYS B CG  1 
ATOM   3735  C CD  . LYS B 1 39  ? 18.037  -29.711 -1.232   1.00 64.62  ? 32   LYS B CD  1 
ATOM   3736  C CE  . LYS B 1 39  ? 16.951  -30.642 -0.726   1.00 71.96  ? 32   LYS B CE  1 
ATOM   3737  N NZ  . LYS B 1 39  ? 17.330  -31.225 0.587    1.00 74.73  ? 32   LYS B NZ  1 
ATOM   3738  N N   . ALA B 1 40  ? 14.132  -25.539 -1.230   1.00 33.88  ? 33   ALA B N   1 
ATOM   3739  C CA  . ALA B 1 40  ? 12.677  -25.282 -1.298   1.00 34.10  ? 33   ALA B CA  1 
ATOM   3740  C C   . ALA B 1 40  ? 12.412  -24.080 -2.210   1.00 35.67  ? 33   ALA B C   1 
ATOM   3741  O O   . ALA B 1 40  ? 11.437  -24.151 -2.996   1.00 36.80  ? 33   ALA B O   1 
ATOM   3742  C CB  . ALA B 1 40  ? 12.109  -25.063 0.081    1.00 33.57  ? 33   ALA B CB  1 
ATOM   3743  N N   . LEU B 1 41  ? 13.235  -23.027 -2.115   1.00 33.72  ? 34   LEU B N   1 
ATOM   3744  C CA  . LEU B 1 41  ? 13.038  -21.779 -2.899   1.00 32.80  ? 34   LEU B CA  1 
ATOM   3745  C C   . LEU B 1 41  ? 13.416  -22.025 -4.366   1.00 30.42  ? 34   LEU B C   1 
ATOM   3746  O O   . LEU B 1 41  ? 12.664  -21.605 -5.249   1.00 28.72  ? 34   LEU B O   1 
ATOM   3747  C CB  . LEU B 1 41  ? 13.862  -20.641 -2.296   1.00 31.55  ? 34   LEU B CB  1 
ATOM   3748  C CG  . LEU B 1 41  ? 13.904  -19.370 -3.142   1.00 32.51  ? 34   LEU B CG  1 
ATOM   3749  C CD1 . LEU B 1 41  ? 12.537  -18.722 -3.228   1.00 31.06  ? 34   LEU B CD1 1 
ATOM   3750  C CD2 . LEU B 1 41  ? 14.926  -18.391 -2.596   1.00 32.68  ? 34   LEU B CD2 1 
ATOM   3751  N N   . ASN B 1 42  ? 14.544  -22.675 -4.609   1.00 29.03  ? 35   ASN B N   1 
ATOM   3752  C CA  . ASN B 1 42  ? 14.969  -23.035 -5.984   1.00 32.10  ? 35   ASN B CA  1 
ATOM   3753  C C   . ASN B 1 42  ? 13.832  -23.827 -6.641   1.00 32.93  ? 35   ASN B C   1 
ATOM   3754  O O   . ASN B 1 42  ? 13.437  -23.453 -7.764   1.00 34.28  ? 35   ASN B O   1 
ATOM   3755  C CB  . ASN B 1 42  ? 16.309  -23.774 -5.987   1.00 33.57  ? 35   ASN B CB  1 
ATOM   3756  C CG  . ASN B 1 42  ? 17.502  -22.849 -5.835   1.00 35.63  ? 35   ASN B CG  1 
ATOM   3757  O OD1 . ASN B 1 42  ? 17.412  -21.794 -5.223   1.00 35.56  ? 35   ASN B OD1 1 
ATOM   3758  N ND2 . ASN B 1 42  ? 18.632  -23.229 -6.403   1.00 40.71  ? 35   ASN B ND2 1 
ATOM   3759  N N   . ARG B 1 43  ? 13.309  -24.847 -5.955   1.00 33.82  ? 36   ARG B N   1 
ATOM   3760  C CA  . ARG B 1 43  ? 12.252  -25.765 -6.458   1.00 36.03  ? 36   ARG B CA  1 
ATOM   3761  C C   . ARG B 1 43  ? 11.007  -24.932 -6.795   1.00 32.79  ? 36   ARG B C   1 
ATOM   3762  O O   . ARG B 1 43  ? 10.385  -25.187 -7.848   1.00 31.04  ? 36   ARG B O   1 
ATOM   3763  C CB  . ARG B 1 43  ? 12.004  -26.870 -5.418   1.00 44.44  ? 36   ARG B CB  1 
ATOM   3764  C CG  . ARG B 1 43  ? 10.876  -27.850 -5.727   1.00 54.23  ? 36   ARG B CG  1 
ATOM   3765  C CD  . ARG B 1 43  ? 10.948  -29.134 -4.921   1.00 62.80  ? 36   ARG B CD  1 
ATOM   3766  N NE  . ARG B 1 43  ? 10.959  -28.943 -3.473   1.00 75.99  ? 36   ARG B NE  1 
ATOM   3767  C CZ  . ARG B 1 43  ? 11.995  -29.171 -2.644   1.00 86.67  ? 36   ARG B CZ  1 
ATOM   3768  N NH1 . ARG B 1 43  ? 13.174  -29.582 -3.094   1.00 92.32  ? 36   ARG B NH1 1 
ATOM   3769  N NH2 . ARG B 1 43  ? 11.854  -28.966 -1.342   1.00 81.35  ? 36   ARG B NH2 1 
ATOM   3770  N N   . GLU B 1 44  ? 10.674  -23.946 -5.962   1.00 32.65  ? 37   GLU B N   1 
ATOM   3771  C CA  . GLU B 1 44  ? 9.497   -23.062 -6.168   1.00 33.85  ? 37   GLU B CA  1 
ATOM   3772  C C   . GLU B 1 44  ? 9.720   -22.194 -7.404   1.00 30.24  ? 37   GLU B C   1 
ATOM   3773  O O   . GLU B 1 44  ? 8.824   -22.150 -8.253   1.00 31.82  ? 37   GLU B O   1 
ATOM   3774  C CB  . GLU B 1 44  ? 9.272   -22.134 -4.976   1.00 35.56  ? 37   GLU B CB  1 
ATOM   3775  C CG  . GLU B 1 44  ? 8.121   -22.524 -4.085   1.00 37.98  ? 37   GLU B CG  1 
ATOM   3776  C CD  . GLU B 1 44  ? 7.968   -21.598 -2.891   1.00 41.71  ? 37   GLU B CD  1 
ATOM   3777  O OE1 . GLU B 1 44  ? 9.004   -21.346 -2.216   1.00 39.25  ? 37   GLU B OE1 1 
ATOM   3778  O OE2 . GLU B 1 44  ? 6.822   -21.118 -2.656   1.00 47.98  ? 37   GLU B OE2 1 
ATOM   3779  N N   . VAL B 1 45  ? 10.864  -21.513 -7.477   1.00 26.94  ? 38   VAL B N   1 
ATOM   3780  C CA  . VAL B 1 45  ? 11.148  -20.510 -8.542   1.00 27.08  ? 38   VAL B CA  1 
ATOM   3781  C C   . VAL B 1 45  ? 11.082  -21.215 -9.910   1.00 27.60  ? 38   VAL B C   1 
ATOM   3782  O O   . VAL B 1 45  ? 10.517  -20.638 -10.835  1.00 28.04  ? 38   VAL B O   1 
ATOM   3783  C CB  . VAL B 1 45  ? 12.486  -19.787 -8.293   1.00 24.98  ? 38   VAL B CB  1 
ATOM   3784  C CG1 . VAL B 1 45  ? 12.953  -18.999 -9.499   1.00 25.93  ? 38   VAL B CG1 1 
ATOM   3785  C CG2 . VAL B 1 45  ? 12.399  -18.862 -7.098   1.00 25.17  ? 38   VAL B CG2 1 
ATOM   3786  N N   . ILE B 1 46  ? 11.588  -22.443 -10.021  1.00 28.32  ? 39   ILE B N   1 
ATOM   3787  C CA  . ILE B 1 46  ? 11.605  -23.209 -11.298  1.00 28.28  ? 39   ILE B CA  1 
ATOM   3788  C C   . ILE B 1 46  ? 10.172  -23.592 -11.659  1.00 29.16  ? 39   ILE B C   1 
ATOM   3789  O O   . ILE B 1 46  ? 9.799   -23.377 -12.813  1.00 28.71  ? 39   ILE B O   1 
ATOM   3790  C CB  . ILE B 1 46  ? 12.539  -24.429 -11.205  1.00 29.27  ? 39   ILE B CB  1 
ATOM   3791  C CG1 . ILE B 1 46  ? 13.997  -23.981 -11.119  1.00 31.44  ? 39   ILE B CG1 1 
ATOM   3792  C CG2 . ILE B 1 46  ? 12.336  -25.378 -12.369  1.00 29.78  ? 39   ILE B CG2 1 
ATOM   3793  C CD1 . ILE B 1 46  ? 14.966  -25.095 -10.799  1.00 34.32  ? 39   ILE B CD1 1 
ATOM   3794  N N   . GLU B 1 47  ? 9.412   -24.132 -10.711  1.00 30.06  ? 40   GLU B N   1 
ATOM   3795  C CA  . GLU B 1 47  ? 7.984   -24.485 -10.911  1.00 32.51  ? 40   GLU B CA  1 
ATOM   3796  C C   . GLU B 1 47  ? 7.231   -23.224 -11.356  1.00 32.40  ? 40   GLU B C   1 
ATOM   3797  O O   . GLU B 1 47  ? 6.483   -23.320 -12.358  1.00 30.52  ? 40   GLU B O   1 
ATOM   3798  C CB  . GLU B 1 47  ? 7.411   -25.113 -9.641   1.00 37.02  ? 40   GLU B CB  1 
ATOM   3799  C CG  . GLU B 1 47  ? 5.903   -25.320 -9.636   1.00 42.21  ? 40   GLU B CG  1 
ATOM   3800  C CD  . GLU B 1 47  ? 5.333   -26.330 -10.619  1.00 49.36  ? 40   GLU B CD  1 
ATOM   3801  O OE1 . GLU B 1 47  ? 6.129   -27.032 -11.299  1.00 55.75  ? 40   GLU B OE1 1 
ATOM   3802  O OE2 . GLU B 1 47  ? 4.077   -26.403 -10.706  1.00 55.98  ? 40   GLU B OE2 1 
ATOM   3803  N N   . TYR B 1 48  ? 7.427   -22.082 -10.685  1.00 30.50  ? 41   TYR B N   1 
ATOM   3804  C CA  . TYR B 1 48  ? 6.675   -20.830 -10.978  1.00 30.55  ? 41   TYR B CA  1 
ATOM   3805  C C   . TYR B 1 48  ? 7.133   -20.195 -12.308  1.00 30.24  ? 41   TYR B C   1 
ATOM   3806  O O   . TYR B 1 48  ? 6.282   -19.600 -12.984  1.00 27.08  ? 41   TYR B O   1 
ATOM   3807  C CB  . TYR B 1 48  ? 6.734   -19.835 -9.818   1.00 29.99  ? 41   TYR B CB  1 
ATOM   3808  C CG  . TYR B 1 48  ? 6.149   -20.327 -8.518   1.00 34.71  ? 41   TYR B CG  1 
ATOM   3809  C CD1 . TYR B 1 48  ? 5.364   -21.471 -8.438   1.00 37.74  ? 41   TYR B CD1 1 
ATOM   3810  C CD2 . TYR B 1 48  ? 6.380   -19.633 -7.343   1.00 37.86  ? 41   TYR B CD2 1 
ATOM   3811  C CE1 . TYR B 1 48  ? 4.854   -21.928 -7.230   1.00 39.26  ? 41   TYR B CE1 1 
ATOM   3812  C CE2 . TYR B 1 48  ? 5.874   -20.070 -6.127   1.00 40.77  ? 41   TYR B CE2 1 
ATOM   3813  C CZ  . TYR B 1 48  ? 5.118   -21.230 -6.061   1.00 41.73  ? 41   TYR B CZ  1 
ATOM   3814  O OH  . TYR B 1 48  ? 4.634   -21.663 -4.852   1.00 42.36  ? 41   TYR B OH  1 
ATOM   3815  N N   . PHE B 1 49  ? 8.413   -20.284 -12.698  1.00 31.26  ? 42   PHE B N   1 
ATOM   3816  C CA  . PHE B 1 49  ? 8.878   -19.778 -14.028  1.00 27.26  ? 42   PHE B CA  1 
ATOM   3817  C C   . PHE B 1 49  ? 8.135   -20.555 -15.108  1.00 28.14  ? 42   PHE B C   1 
ATOM   3818  O O   . PHE B 1 49  ? 7.598   -19.943 -16.030  1.00 28.34  ? 42   PHE B O   1 
ATOM   3819  C CB  . PHE B 1 49  ? 10.397  -19.867 -14.193  1.00 26.18  ? 42   PHE B CB  1 
ATOM   3820  C CG  . PHE B 1 49  ? 11.090  -18.528 -14.081  1.00 25.52  ? 42   PHE B CG  1 
ATOM   3821  C CD1 . PHE B 1 49  ? 11.463  -18.016 -12.843  1.00 23.47  ? 42   PHE B CD1 1 
ATOM   3822  C CD2 . PHE B 1 49  ? 11.352  -17.761 -15.207  1.00 24.61  ? 42   PHE B CD2 1 
ATOM   3823  C CE1 . PHE B 1 49  ? 12.066  -16.773 -12.725  1.00 22.24  ? 42   PHE B CE1 1 
ATOM   3824  C CE2 . PHE B 1 49  ? 11.950  -16.514 -15.088  1.00 24.17  ? 42   PHE B CE2 1 
ATOM   3825  C CZ  . PHE B 1 49  ? 12.295  -16.019 -13.846  1.00 23.90  ? 42   PHE B CZ  1 
ATOM   3826  N N   . LYS B 1 50  ? 8.075   -21.872 -14.926  1.00 30.85  ? 43   LYS B N   1 
ATOM   3827  C CA  . LYS B 1 50  ? 7.422   -22.867 -15.810  1.00 32.68  ? 43   LYS B CA  1 
ATOM   3828  C C   . LYS B 1 50  ? 5.915   -22.594 -15.901  1.00 33.84  ? 43   LYS B C   1 
ATOM   3829  O O   . LYS B 1 50  ? 5.367   -22.687 -17.023  1.00 36.58  ? 43   LYS B O   1 
ATOM   3830  C CB  . LYS B 1 50  ? 7.734   -24.256 -15.249  1.00 37.14  ? 43   LYS B CB  1 
ATOM   3831  C CG  . LYS B 1 50  ? 7.075   -25.431 -15.936  1.00 45.50  ? 43   LYS B CG  1 
ATOM   3832  C CD  . LYS B 1 50  ? 7.674   -26.758 -15.515  1.00 53.96  ? 43   LYS B CD  1 
ATOM   3833  C CE  . LYS B 1 50  ? 6.733   -27.913 -15.796  1.00 61.42  ? 43   LYS B CE  1 
ATOM   3834  N NZ  . LYS B 1 50  ? 5.644   -27.985 -14.790  1.00 67.34  ? 43   LYS B NZ  1 
ATOM   3835  N N   . GLU B 1 51  ? 5.248   -22.277 -14.787  1.00 29.75  ? 44   GLU B N   1 
ATOM   3836  C CA  . GLU B 1 51  ? 3.766   -22.241 -14.736  1.00 30.61  ? 44   GLU B CA  1 
ATOM   3837  C C   . GLU B 1 51  ? 3.225   -20.817 -14.901  1.00 29.82  ? 44   GLU B C   1 
ATOM   3838  O O   . GLU B 1 51  ? 1.993   -20.710 -15.167  1.00 28.27  ? 44   GLU B O   1 
ATOM   3839  C CB  . GLU B 1 51  ? 3.229   -22.842 -13.437  1.00 32.92  ? 44   GLU B CB  1 
ATOM   3840  C CG  . GLU B 1 51  ? 3.377   -24.343 -13.360  1.00 36.24  ? 44   GLU B CG  1 
ATOM   3841  C CD  . GLU B 1 51  ? 2.707   -25.111 -14.481  1.00 41.20  ? 44   GLU B CD  1 
ATOM   3842  O OE1 . GLU B 1 51  ? 1.548   -24.804 -14.817  1.00 45.76  ? 44   GLU B OE1 1 
ATOM   3843  O OE2 . GLU B 1 51  ? 3.351   -26.021 -15.023  1.00 49.07  ? 44   GLU B OE2 1 
ATOM   3844  N N   . HIS B 1 52  ? 4.041   -19.763 -14.747  1.00 25.49  ? 45   HIS B N   1 
ATOM   3845  C CA  . HIS B 1 52  ? 3.494   -18.378 -14.627  1.00 24.34  ? 45   HIS B CA  1 
ATOM   3846  C C   . HIS B 1 52  ? 4.340   -17.284 -15.293  1.00 22.08  ? 45   HIS B C   1 
ATOM   3847  O O   . HIS B 1 52  ? 3.833   -16.145 -15.367  1.00 20.06  ? 45   HIS B O   1 
ATOM   3848  C CB  . HIS B 1 52  ? 3.274   -18.052 -13.159  1.00 24.91  ? 45   HIS B CB  1 
ATOM   3849  C CG  . HIS B 1 52  ? 2.337   -18.994 -12.494  1.00 26.95  ? 45   HIS B CG  1 
ATOM   3850  N ND1 . HIS B 1 52  ? 1.028   -19.119 -12.898  1.00 28.90  ? 45   HIS B ND1 1 
ATOM   3851  C CD2 . HIS B 1 52  ? 2.505   -19.855 -11.464  1.00 28.06  ? 45   HIS B CD2 1 
ATOM   3852  C CE1 . HIS B 1 52  ? 0.417   -20.011 -12.132  1.00 29.14  ? 45   HIS B CE1 1 
ATOM   3853  N NE2 . HIS B 1 52  ? 1.299   -20.472 -11.229  1.00 28.16  ? 45   HIS B NE2 1 
ATOM   3854  N N   . VAL B 1 53  ? 5.559   -17.584 -15.753  1.00 21.34  ? 46   VAL B N   1 
ATOM   3855  C CA  . VAL B 1 53  ? 6.468   -16.565 -16.362  1.00 21.13  ? 46   VAL B CA  1 
ATOM   3856  C C   . VAL B 1 53  ? 6.760   -16.957 -17.815  1.00 20.83  ? 46   VAL B C   1 
ATOM   3857  O O   . VAL B 1 53  ? 6.300   -16.236 -18.712  1.00 19.11  ? 46   VAL B O   1 
ATOM   3858  C CB  . VAL B 1 53  ? 7.771   -16.388 -15.570  1.00 20.64  ? 46   VAL B CB  1 
ATOM   3859  C CG1 . VAL B 1 53  ? 8.570   -15.206 -16.116  1.00 21.48  ? 46   VAL B CG1 1 
ATOM   3860  C CG2 . VAL B 1 53  ? 7.519   -16.245 -14.083  1.00 20.00  ? 46   VAL B CG2 1 
ATOM   3861  N N   . ASN B 1 54  ? 7.496   -18.053 -18.021  1.00 20.15  ? 47   ASN B N   1 
ATOM   3862  C CA  . ASN B 1 54  ? 7.872   -18.541 -19.367  1.00 20.34  ? 47   ASN B CA  1 
ATOM   3863  C C   . ASN B 1 54  ? 8.701   -19.817 -19.254  1.00 22.06  ? 47   ASN B C   1 
ATOM   3864  O O   . ASN B 1 54  ? 9.878   -19.745 -18.921  1.00 24.28  ? 47   ASN B O   1 
ATOM   3865  C CB  . ASN B 1 54  ? 8.663   -17.470 -20.124  1.00 19.62  ? 47   ASN B CB  1 
ATOM   3866  C CG  . ASN B 1 54  ? 8.634   -17.690 -21.619  1.00 18.35  ? 47   ASN B CG  1 
ATOM   3867  O OD1 . ASN B 1 54  ? 8.806   -18.816 -22.080  1.00 17.40  ? 47   ASN B OD1 1 
ATOM   3868  N ND2 . ASN B 1 54  ? 8.396   -16.630 -22.372  1.00 17.79  ? 47   ASN B ND2 1 
ATOM   3869  N N   . PRO B 1 55  ? 8.169   -21.017 -19.576  1.00 23.07  ? 48   PRO B N   1 
ATOM   3870  C CA  . PRO B 1 55  ? 8.975   -22.238 -19.553  1.00 24.59  ? 48   PRO B CA  1 
ATOM   3871  C C   . PRO B 1 55  ? 10.122  -22.200 -20.571  1.00 29.68  ? 48   PRO B C   1 
ATOM   3872  O O   . PRO B 1 55  ? 11.050  -22.991 -20.440  1.00 33.56  ? 48   PRO B O   1 
ATOM   3873  C CB  . PRO B 1 55  ? 7.980   -23.342 -19.902  1.00 23.61  ? 48   PRO B CB  1 
ATOM   3874  C CG  . PRO B 1 55  ? 6.941   -22.616 -20.709  1.00 24.20  ? 48   PRO B CG  1 
ATOM   3875  C CD  . PRO B 1 55  ? 6.795   -21.272 -20.021  1.00 23.85  ? 48   PRO B CD  1 
ATOM   3876  N N   . GLY B 1 56  ? 10.021  -21.294 -21.554  1.00 31.39  ? 49   GLY B N   1 
ATOM   3877  C CA  . GLY B 1 56  ? 11.073  -20.998 -22.541  1.00 30.96  ? 49   GLY B CA  1 
ATOM   3878  C C   . GLY B 1 56  ? 12.359  -20.506 -21.909  1.00 34.38  ? 49   GLY B C   1 
ATOM   3879  O O   . GLY B 1 56  ? 13.413  -20.914 -22.406  1.00 35.02  ? 49   GLY B O   1 
ATOM   3880  N N   . PHE B 1 57  ? 12.297  -19.653 -20.880  1.00 39.54  ? 50   PHE B N   1 
ATOM   3881  C CA  . PHE B 1 57  ? 13.505  -19.144 -20.172  1.00 40.43  ? 50   PHE B CA  1 
ATOM   3882  C C   . PHE B 1 57  ? 14.287  -20.313 -19.597  1.00 37.06  ? 50   PHE B C   1 
ATOM   3883  O O   . PHE B 1 57  ? 15.516  -20.263 -19.677  1.00 42.60  ? 50   PHE B O   1 
ATOM   3884  C CB  . PHE B 1 57  ? 13.213  -18.201 -19.009  1.00 49.11  ? 50   PHE B CB  1 
ATOM   3885  C CG  . PHE B 1 57  ? 13.096  -16.767 -19.430  1.00 61.52  ? 50   PHE B CG  1 
ATOM   3886  C CD1 . PHE B 1 57  ? 14.214  -16.057 -19.854  1.00 69.20  ? 50   PHE B CD1 1 
ATOM   3887  C CD2 . PHE B 1 57  ? 11.855  -16.140 -19.440  1.00 66.65  ? 50   PHE B CD2 1 
ATOM   3888  C CE1 . PHE B 1 57  ? 14.084  -14.740 -20.274  1.00 80.97  ? 50   PHE B CE1 1 
ATOM   3889  C CE2 . PHE B 1 57  ? 11.724  -14.820 -19.848  1.00 73.83  ? 50   PHE B CE2 1 
ATOM   3890  C CZ  . PHE B 1 57  ? 12.840  -14.123 -20.273  1.00 87.47  ? 50   PHE B CZ  1 
ATOM   3891  N N   . LEU B 1 58  ? 13.608  -21.351 -19.101  1.00 34.15  ? 51   LEU B N   1 
ATOM   3892  C CA  . LEU B 1 58  ? 14.282  -22.545 -18.513  1.00 33.89  ? 51   LEU B CA  1 
ATOM   3893  C C   . LEU B 1 58  ? 14.970  -23.365 -19.613  1.00 37.07  ? 51   LEU B C   1 
ATOM   3894  O O   . LEU B 1 58  ? 16.044  -23.947 -19.329  1.00 32.19  ? 51   LEU B O   1 
ATOM   3895  C CB  . LEU B 1 58  ? 13.265  -23.402 -17.757  1.00 34.08  ? 51   LEU B CB  1 
ATOM   3896  C CG  . LEU B 1 58  ? 12.611  -22.732 -16.556  1.00 34.08  ? 51   LEU B CG  1 
ATOM   3897  C CD1 . LEU B 1 58  ? 11.454  -23.555 -16.037  1.00 36.46  ? 51   LEU B CD1 1 
ATOM   3898  C CD2 . LEU B 1 58  ? 13.625  -22.519 -15.457  1.00 37.36  ? 51   LEU B CD2 1 
ATOM   3899  N N   . GLU B 1 59  ? 14.395  -23.418 -20.821  1.00 38.64  ? 52   GLU B N   1 
ATOM   3900  C CA  . GLU B 1 59  ? 14.997  -24.155 -21.967  1.00 40.56  ? 52   GLU B CA  1 
ATOM   3901  C C   . GLU B 1 59  ? 16.255  -23.423 -22.440  1.00 37.75  ? 52   GLU B C   1 
ATOM   3902  O O   . GLU B 1 59  ? 17.230  -24.118 -22.724  1.00 34.14  ? 52   GLU B O   1 
ATOM   3903  C CB  . GLU B 1 59  ? 14.003  -24.319 -23.123  1.00 47.42  ? 52   GLU B CB  1 
ATOM   3904  C CG  . GLU B 1 59  ? 12.873  -25.298 -22.826  1.00 54.16  ? 52   GLU B CG  1 
ATOM   3905  C CD  . GLU B 1 59  ? 13.346  -26.689 -22.438  1.00 61.10  ? 52   GLU B CD  1 
ATOM   3906  O OE1 . GLU B 1 59  ? 13.959  -27.350 -23.295  1.00 66.94  ? 52   GLU B OE1 1 
ATOM   3907  O OE2 . GLU B 1 59  ? 13.144  -27.094 -21.263  1.00 67.43  ? 52   GLU B OE2 1 
ATOM   3908  N N   . TYR B 1 60  ? 16.213  -22.088 -22.550  1.00 40.97  ? 53   TYR B N   1 
ATOM   3909  C CA  . TYR B 1 60  ? 17.328  -21.239 -23.057  1.00 44.57  ? 53   TYR B CA  1 
ATOM   3910  C C   . TYR B 1 60  ? 18.536  -21.367 -22.137  1.00 39.21  ? 53   TYR B C   1 
ATOM   3911  O O   . TYR B 1 60  ? 19.637  -21.640 -22.629  1.00 41.28  ? 53   TYR B O   1 
ATOM   3912  C CB  . TYR B 1 60  ? 16.978  -19.748 -23.132  1.00 51.60  ? 53   TYR B CB  1 
ATOM   3913  C CG  . TYR B 1 60  ? 18.180  -18.829 -23.043  1.00 62.50  ? 53   TYR B CG  1 
ATOM   3914  C CD1 . TYR B 1 60  ? 19.063  -18.672 -24.111  1.00 69.83  ? 53   TYR B CD1 1 
ATOM   3915  C CD2 . TYR B 1 60  ? 18.456  -18.118 -21.883  1.00 66.87  ? 53   TYR B CD2 1 
ATOM   3916  C CE1 . TYR B 1 60  ? 20.161  -17.823 -24.040  1.00 69.35  ? 53   TYR B CE1 1 
ATOM   3917  C CE2 . TYR B 1 60  ? 19.556  -17.274 -21.789  1.00 72.70  ? 53   TYR B CE2 1 
ATOM   3918  C CZ  . TYR B 1 60  ? 20.409  -17.119 -22.874  1.00 77.42  ? 53   TYR B CZ  1 
ATOM   3919  O OH  . TYR B 1 60  ? 21.495  -16.290 -22.808  1.00 83.13  ? 53   TYR B OH  1 
ATOM   3920  N N   . ARG B 1 61  ? 18.322  -21.140 -20.843  1.00 42.16  ? 54   ARG B N   1 
ATOM   3921  C CA  . ARG B 1 61  ? 19.380  -21.143 -19.791  1.00 43.00  ? 54   ARG B CA  1 
ATOM   3922  C C   . ARG B 1 61  ? 20.052  -22.524 -19.733  1.00 44.21  ? 54   ARG B C   1 
ATOM   3923  O O   . ARG B 1 61  ? 21.229  -22.557 -19.388  1.00 43.91  ? 54   ARG B O   1 
ATOM   3924  C CB  . ARG B 1 61  ? 18.768  -20.690 -18.463  1.00 43.64  ? 54   ARG B CB  1 
ATOM   3925  C CG  . ARG B 1 61  ? 18.553  -19.186 -18.359  1.00 44.53  ? 54   ARG B CG  1 
ATOM   3926  C CD  . ARG B 1 61  ? 19.878  -18.476 -18.122  1.00 50.59  ? 54   ARG B CD  1 
ATOM   3927  N NE  . ARG B 1 61  ? 20.600  -19.025 -16.973  1.00 51.53  ? 54   ARG B NE  1 
ATOM   3928  C CZ  . ARG B 1 61  ? 21.833  -19.519 -16.995  1.00 45.88  ? 54   ARG B CZ  1 
ATOM   3929  N NH1 . ARG B 1 61  ? 22.512  -19.605 -18.130  1.00 49.04  ? 54   ARG B NH1 1 
ATOM   3930  N NH2 . ARG B 1 61  ? 22.328  -20.029 -15.890  1.00 44.86  ? 54   ARG B NH2 1 
ATOM   3931  N N   . LYS B 1 62  ? 19.350  -23.607 -20.123  1.00 52.61  ? 55   LYS B N   1 
ATOM   3932  C CA  . LYS B 1 62  ? 19.894  -25.000 -20.233  1.00 56.99  ? 55   LYS B CA  1 
ATOM   3933  C C   . LYS B 1 62  ? 20.905  -25.105 -21.385  1.00 58.70  ? 55   LYS B C   1 
ATOM   3934  O O   . LYS B 1 62  ? 21.973  -25.732 -21.157  1.00 59.35  ? 55   LYS B O   1 
ATOM   3935  C CB  . LYS B 1 62  ? 18.792  -26.049 -20.446  1.00 59.37  ? 55   LYS B CB  1 
ATOM   3936  C CG  . LYS B 1 62  ? 18.184  -26.635 -19.177  1.00 62.02  ? 55   LYS B CG  1 
ATOM   3937  C CD  . LYS B 1 62  ? 17.096  -27.664 -19.447  1.00 61.25  ? 55   LYS B CD  1 
ATOM   3938  C CE  . LYS B 1 62  ? 16.060  -27.770 -18.344  1.00 60.13  ? 55   LYS B CE  1 
ATOM   3939  N NZ  . LYS B 1 62  ? 14.797  -27.104 -18.731  1.00 59.68  ? 55   LYS B NZ  1 
ATOM   3940  N N   . SER B 1 63  ? 20.567  -24.537 -22.561  1.00 55.91  ? 56   SER B N   1 
ATOM   3941  C CA  . SER B 1 63  ? 21.389  -24.496 -23.812  1.00 51.67  ? 56   SER B CA  1 
ATOM   3942  C C   . SER B 1 63  ? 22.716  -23.765 -23.538  1.00 49.97  ? 56   SER B C   1 
ATOM   3943  O O   . SER B 1 63  ? 23.707  -24.039 -24.228  1.00 50.33  ? 56   SER B O   1 
ATOM   3944  C CB  . SER B 1 63  ? 20.605  -23.893 -25.014  1.00 45.04  ? 56   SER B CB  1 
ATOM   3945  O OG  . SER B 1 63  ? 20.568  -22.466 -25.020  1.00 36.99  ? 56   SER B OG  1 
ATOM   3946  N N   . VAL B 1 64  ? 22.730  -22.879 -22.544  1.00 53.59  ? 57   VAL B N   1 
ATOM   3947  C CA  . VAL B 1 64  ? 23.921  -22.067 -22.154  1.00 59.96  ? 57   VAL B CA  1 
ATOM   3948  C C   . VAL B 1 64  ? 24.428  -22.488 -20.745  1.00 65.70  ? 57   VAL B C   1 
ATOM   3949  O O   . VAL B 1 64  ? 24.988  -21.616 -20.020  1.00 60.75  ? 57   VAL B O   1 
ATOM   3950  C CB  . VAL B 1 64  ? 23.599  -20.557 -22.264  1.00 55.84  ? 57   VAL B CB  1 
ATOM   3951  C CG1 . VAL B 1 64  ? 23.502  -20.086 -23.706  1.00 53.85  ? 57   VAL B CG1 1 
ATOM   3952  C CG2 . VAL B 1 64  ? 22.353  -20.164 -21.472  1.00 55.14  ? 57   VAL B CG2 1 
ATOM   3953  N N   . THR B 1 65  ? 24.287  -23.773 -20.371  1.00 65.97  ? 58   THR B N   1 
ATOM   3954  C CA  . THR B 1 65  ? 24.789  -24.356 -19.082  1.00 70.87  ? 58   THR B CA  1 
ATOM   3955  C C   . THR B 1 65  ? 24.934  -25.888 -19.186  1.00 78.12  ? 58   THR B C   1 
ATOM   3956  O O   . THR B 1 65  ? 24.324  -26.494 -20.106  1.00 78.75  ? 58   THR B O   1 
ATOM   3957  C CB  . THR B 1 65  ? 23.877  -24.041 -17.880  1.00 64.10  ? 58   THR B CB  1 
ATOM   3958  O OG1 . THR B 1 65  ? 22.559  -24.510 -18.157  1.00 60.21  ? 58   THR B OG1 1 
ATOM   3959  C CG2 . THR B 1 65  ? 23.807  -22.573 -17.531  1.00 59.43  ? 58   THR B CG2 1 
ATOM   3960  N N   . ALA B 1 66  ? 25.675  -26.498 -18.249  1.00 79.42  ? 59   ALA B N   1 
ATOM   3961  C CA  . ALA B 1 66  ? 25.606  -27.941 -17.918  1.00 81.02  ? 59   ALA B CA  1 
ATOM   3962  C C   . ALA B 1 66  ? 24.525  -28.109 -16.843  1.00 88.81  ? 59   ALA B C   1 
ATOM   3963  O O   . ALA B 1 66  ? 24.781  -27.695 -15.697  1.00 84.71  ? 59   ALA B O   1 
ATOM   3964  C CB  . ALA B 1 66  ? 26.949  -28.466 -17.466  1.00 77.30  ? 59   ALA B CB  1 
ATOM   3965  N N   . GLY B 1 67  ? 23.353  -28.640 -17.229  1.00 100.15 ? 60   GLY B N   1 
ATOM   3966  C CA  . GLY B 1 67  ? 22.168  -28.909 -16.377  1.00 97.96  ? 60   GLY B CA  1 
ATOM   3967  C C   . GLY B 1 67  ? 22.489  -28.921 -14.889  1.00 97.11  ? 60   GLY B C   1 
ATOM   3968  O O   . GLY B 1 67  ? 23.587  -29.363 -14.515  1.00 99.43  ? 60   GLY B O   1 
ATOM   3969  N N   . GLY B 1 68  ? 21.547  -28.486 -14.053  1.00 95.99  ? 61   GLY B N   1 
ATOM   3970  C CA  . GLY B 1 68  ? 21.775  -28.193 -12.624  1.00 82.67  ? 61   GLY B CA  1 
ATOM   3971  C C   . GLY B 1 68  ? 22.246  -26.765 -12.443  1.00 73.48  ? 61   GLY B C   1 
ATOM   3972  O O   . GLY B 1 68  ? 21.802  -26.127 -11.488  1.00 71.04  ? 61   GLY B O   1 
ATOM   3973  N N   . ASP B 1 69  ? 23.102  -26.286 -13.350  1.00 69.52  ? 62   ASP B N   1 
ATOM   3974  C CA  . ASP B 1 69  ? 23.601  -24.885 -13.408  1.00 67.73  ? 62   ASP B CA  1 
ATOM   3975  C C   . ASP B 1 69  ? 22.533  -23.948 -13.989  1.00 64.80  ? 62   ASP B C   1 
ATOM   3976  O O   . ASP B 1 69  ? 22.538  -22.767 -13.604  1.00 61.85  ? 62   ASP B O   1 
ATOM   3977  C CB  . ASP B 1 69  ? 24.913  -24.770 -14.198  1.00 70.74  ? 62   ASP B CB  1 
ATOM   3978  C CG  . ASP B 1 69  ? 26.157  -24.716 -13.317  1.00 77.94  ? 62   ASP B CG  1 
ATOM   3979  O OD1 . ASP B 1 69  ? 26.066  -24.131 -12.220  1.00 73.58  ? 62   ASP B OD1 1 
ATOM   3980  O OD2 . ASP B 1 69  ? 27.226  -25.226 -13.732  1.00 81.43  ? 62   ASP B OD2 1 
ATOM   3981  N N   . TYR B 1 70  ? 21.650  -24.409 -14.879  1.00 65.25  ? 63   TYR B N   1 
ATOM   3982  C CA  . TYR B 1 70  ? 20.581  -23.560 -15.485  1.00 57.27  ? 63   TYR B CA  1 
ATOM   3983  C C   . TYR B 1 70  ? 19.671  -23.032 -14.373  1.00 60.34  ? 63   TYR B C   1 
ATOM   3984  O O   . TYR B 1 70  ? 19.168  -21.895 -14.503  1.00 56.54  ? 63   TYR B O   1 
ATOM   3985  C CB  . TYR B 1 70  ? 19.767  -24.353 -16.501  1.00 50.47  ? 63   TYR B CB  1 
ATOM   3986  C CG  . TYR B 1 70  ? 18.675  -25.188 -15.891  1.00 53.34  ? 63   TYR B CG  1 
ATOM   3987  C CD1 . TYR B 1 70  ? 18.935  -26.456 -15.398  1.00 57.27  ? 63   TYR B CD1 1 
ATOM   3988  C CD2 . TYR B 1 70  ? 17.378  -24.711 -15.799  1.00 47.65  ? 63   TYR B CD2 1 
ATOM   3989  C CE1 . TYR B 1 70  ? 17.931  -27.231 -14.830  1.00 60.28  ? 63   TYR B CE1 1 
ATOM   3990  C CE2 . TYR B 1 70  ? 16.362  -25.476 -15.250  1.00 56.11  ? 63   TYR B CE2 1 
ATOM   3991  C CZ  . TYR B 1 70  ? 16.635  -26.738 -14.748  1.00 60.14  ? 63   TYR B CZ  1 
ATOM   3992  O OH  . TYR B 1 70  ? 15.614  -27.468 -14.189  1.00 60.36  ? 63   TYR B OH  1 
ATOM   3993  N N   . GLY B 1 71  ? 19.494  -23.856 -13.324  1.00 65.38  ? 64   GLY B N   1 
ATOM   3994  C CA  . GLY B 1 71  ? 18.640  -23.608 -12.138  1.00 70.25  ? 64   GLY B CA  1 
ATOM   3995  C C   . GLY B 1 71  ? 19.383  -22.896 -11.018  1.00 62.19  ? 64   GLY B C   1 
ATOM   3996  O O   . GLY B 1 71  ? 19.211  -23.275 -9.825   1.00 65.24  ? 64   GLY B O   1 
ATOM   3997  N N   . ALA B 1 72  ? 20.235  -21.940 -11.395  1.00 52.67  ? 65   ALA B N   1 
ATOM   3998  C CA  . ALA B 1 72  ? 20.861  -20.956 -10.486  1.00 40.82  ? 65   ALA B CA  1 
ATOM   3999  C C   . ALA B 1 72  ? 19.885  -19.788 -10.326  1.00 37.73  ? 65   ALA B C   1 
ATOM   4000  O O   . ALA B 1 72  ? 19.364  -19.275 -11.380  1.00 31.35  ? 65   ALA B O   1 
ATOM   4001  C CB  . ALA B 1 72  ? 22.183  -20.502 -11.031  1.00 39.45  ? 65   ALA B CB  1 
ATOM   4002  N N   . VAL B 1 73  ? 19.622  -19.411 -9.068   1.00 32.94  ? 66   VAL B N   1 
ATOM   4003  C CA  . VAL B 1 73  ? 18.628  -18.368 -8.693   1.00 31.38  ? 66   VAL B CA  1 
ATOM   4004  C C   . VAL B 1 73  ? 19.365  -17.201 -8.044   1.00 30.31  ? 66   VAL B C   1 
ATOM   4005  O O   . VAL B 1 73  ? 20.037  -17.438 -7.041   1.00 30.84  ? 66   VAL B O   1 
ATOM   4006  C CB  . VAL B 1 73  ? 17.549  -18.953 -7.764   1.00 31.02  ? 66   VAL B CB  1 
ATOM   4007  C CG1 . VAL B 1 73  ? 16.435  -17.958 -7.474   1.00 30.72  ? 66   VAL B CG1 1 
ATOM   4008  C CG2 . VAL B 1 73  ? 16.976  -20.244 -8.336   1.00 30.78  ? 66   VAL B CG2 1 
ATOM   4009  N N   . GLU B 1 74  ? 19.238  -16.001 -8.612   1.00 32.28  ? 67   GLU B N   1 
ATOM   4010  C CA  . GLU B 1 74  ? 19.781  -14.729 -8.070   1.00 36.87  ? 67   GLU B CA  1 
ATOM   4011  C C   . GLU B 1 74  ? 19.348  -14.565 -6.624   1.00 34.48  ? 67   GLU B C   1 
ATOM   4012  O O   . GLU B 1 74  ? 18.187  -14.880 -6.373   1.00 37.50  ? 67   GLU B O   1 
ATOM   4013  C CB  . GLU B 1 74  ? 19.259  -13.521 -8.850   1.00 41.50  ? 67   GLU B CB  1 
ATOM   4014  C CG  . GLU B 1 74  ? 20.349  -12.825 -9.629   1.00 45.74  ? 67   GLU B CG  1 
ATOM   4015  C CD  . GLU B 1 74  ? 19.882  -12.088 -10.859  1.00 50.95  ? 67   GLU B CD  1 
ATOM   4016  O OE1 . GLU B 1 74  ? 18.689  -12.228 -11.213  1.00 59.72  ? 67   GLU B OE1 1 
ATOM   4017  O OE2 . GLU B 1 74  ? 20.724  -11.395 -11.458  1.00 52.36  ? 67   GLU B OE2 1 
ATOM   4018  N N   . TRP B 1 75  ? 20.223  -14.044 -5.757   1.00 30.17  ? 68   TRP B N   1 
ATOM   4019  C CA  . TRP B 1 75  ? 19.886  -13.818 -4.327   1.00 30.11  ? 68   TRP B CA  1 
ATOM   4020  C C   . TRP B 1 75  ? 20.272  -12.399 -3.884   1.00 29.90  ? 68   TRP B C   1 
ATOM   4021  O O   . TRP B 1 75  ? 19.395  -11.666 -3.419   1.00 25.87  ? 68   TRP B O   1 
ATOM   4022  C CB  . TRP B 1 75  ? 20.523  -14.912 -3.475   1.00 30.29  ? 68   TRP B CB  1 
ATOM   4023  C CG  . TRP B 1 75  ? 20.153  -14.840 -2.031   1.00 34.40  ? 68   TRP B CG  1 
ATOM   4024  C CD1 . TRP B 1 75  ? 21.005  -14.717 -0.974   1.00 34.30  ? 68   TRP B CD1 1 
ATOM   4025  C CD2 . TRP B 1 75  ? 18.826  -14.874 -1.471   1.00 35.92  ? 68   TRP B CD2 1 
ATOM   4026  N NE1 . TRP B 1 75  ? 20.298  -14.685 0.198    1.00 35.09  ? 68   TRP B NE1 1 
ATOM   4027  C CE2 . TRP B 1 75  ? 18.962  -14.761 -0.075   1.00 35.06  ? 68   TRP B CE2 1 
ATOM   4028  C CE3 . TRP B 1 75  ? 17.534  -14.963 -2.009   1.00 39.61  ? 68   TRP B CE3 1 
ATOM   4029  C CZ2 . TRP B 1 75  ? 17.867  -14.753 0.778    1.00 35.27  ? 68   TRP B CZ2 1 
ATOM   4030  C CZ3 . TRP B 1 75  ? 16.450  -14.937 -1.163   1.00 37.09  ? 68   TRP B CZ3 1 
ATOM   4031  C CH2 . TRP B 1 75  ? 16.618  -14.851 0.211    1.00 35.76  ? 68   TRP B CH2 1 
ATOM   4032  N N   . GLN B 1 76  ? 21.531  -11.995 -4.047   1.00 33.40  ? 69   GLN B N   1 
ATOM   4033  C CA  . GLN B 1 76  ? 21.949  -10.610 -3.706   1.00 34.08  ? 69   GLN B CA  1 
ATOM   4034  C C   . GLN B 1 76  ? 23.276  -10.286 -4.383   1.00 33.56  ? 69   GLN B C   1 
ATOM   4035  O O   . GLN B 1 76  ? 23.945  -11.222 -4.860   1.00 35.56  ? 69   GLN B O   1 
ATOM   4036  C CB  . GLN B 1 76  ? 22.034  -10.408 -2.186   1.00 34.54  ? 69   GLN B CB  1 
ATOM   4037  C CG  . GLN B 1 76  ? 23.099  -11.239 -1.493   1.00 34.75  ? 69   GLN B CG  1 
ATOM   4038  C CD  . GLN B 1 76  ? 22.934  -11.276 0.020    1.00 36.74  ? 69   GLN B CD  1 
ATOM   4039  O OE1 . GLN B 1 76  ? 22.235  -10.464 0.642    1.00 36.61  ? 69   GLN B OE1 1 
ATOM   4040  N NE2 . GLN B 1 76  ? 23.558  -12.267 0.641    1.00 33.89  ? 69   GLN B NE2 1 
ATOM   4041  N N   . ALA B 1 77  ? 23.586  -8.986  -4.445   1.00 33.60  ? 70   ALA B N   1 
ATOM   4042  C CA  . ALA B 1 77  ? 24.904  -8.414  -4.793   1.00 35.81  ? 70   ALA B CA  1 
ATOM   4043  C C   . ALA B 1 77  ? 25.950  -8.905  -3.780   1.00 37.18  ? 70   ALA B C   1 
ATOM   4044  O O   . ALA B 1 77  ? 25.638  -8.887  -2.571   1.00 39.89  ? 70   ALA B O   1 
ATOM   4045  C CB  . ALA B 1 77  ? 24.812  -6.905  -4.793   1.00 34.18  ? 70   ALA B CB  1 
ATOM   4046  N N   . GLY B 1 78  ? 27.126  -9.334  -4.258   1.00 35.50  ? 71   GLY B N   1 
ATOM   4047  C CA  . GLY B 1 78  ? 28.281  -9.714  -3.424   1.00 33.84  ? 71   GLY B CA  1 
ATOM   4048  C C   . GLY B 1 78  ? 29.113  -8.498  -3.070   1.00 33.32  ? 71   GLY B C   1 
ATOM   4049  O O   . GLY B 1 78  ? 28.979  -7.974  -1.973   1.00 41.50  ? 71   GLY B O   1 
ATOM   4050  N N   . SER B 1 79  ? 29.953  -8.056  -3.990   1.00 34.43  ? 72   SER B N   1 
ATOM   4051  C CA  . SER B 1 79  ? 30.705  -6.780  -3.938   1.00 32.73  ? 72   SER B CA  1 
ATOM   4052  C C   . SER B 1 79  ? 30.188  -5.911  -5.084   1.00 31.39  ? 72   SER B C   1 
ATOM   4053  O O   . SER B 1 79  ? 29.188  -6.315  -5.697   1.00 30.55  ? 72   SER B O   1 
ATOM   4054  C CB  . SER B 1 79  ? 32.170  -7.068  -4.044   1.00 34.16  ? 72   SER B CB  1 
ATOM   4055  O OG  . SER B 1 79  ? 32.412  -7.994  -5.096   1.00 35.91  ? 72   SER B OG  1 
ATOM   4056  N N   . LEU B 1 80  ? 30.848  -4.796  -5.393   1.00 30.58  ? 73   LEU B N   1 
ATOM   4057  C CA  . LEU B 1 80  ? 30.477  -3.922  -6.537   1.00 29.66  ? 73   LEU B CA  1 
ATOM   4058  C C   . LEU B 1 80  ? 30.300  -4.753  -7.805   1.00 28.95  ? 73   LEU B C   1 
ATOM   4059  O O   . LEU B 1 80  ? 29.404  -4.410  -8.583   1.00 27.70  ? 73   LEU B O   1 
ATOM   4060  C CB  . LEU B 1 80  ? 31.546  -2.858  -6.782   1.00 30.19  ? 73   LEU B CB  1 
ATOM   4061  C CG  . LEU B 1 80  ? 31.310  -1.524  -6.078   1.00 32.33  ? 73   LEU B CG  1 
ATOM   4062  C CD1 . LEU B 1 80  ? 32.545  -0.638  -6.179   1.00 33.08  ? 73   LEU B CD1 1 
ATOM   4063  C CD2 . LEU B 1 80  ? 30.092  -0.810  -6.634   1.00 29.69  ? 73   LEU B CD2 1 
ATOM   4064  N N   . ASN B 1 81  ? 31.131  -5.776  -8.017   1.00 27.25  ? 74   ASN B N   1 
ATOM   4065  C CA  . ASN B 1 81  ? 31.261  -6.411  -9.348   1.00 25.53  ? 74   ASN B CA  1 
ATOM   4066  C C   . ASN B 1 81  ? 30.869  -7.890  -9.301   1.00 24.29  ? 74   ASN B C   1 
ATOM   4067  O O   . ASN B 1 81  ? 31.124  -8.591  -10.304  1.00 24.43  ? 74   ASN B O   1 
ATOM   4068  C CB  . ASN B 1 81  ? 32.667  -6.215  -9.899   1.00 26.12  ? 74   ASN B CB  1 
ATOM   4069  C CG  . ASN B 1 81  ? 33.124  -4.773  -9.833   1.00 26.65  ? 74   ASN B CG  1 
ATOM   4070  O OD1 . ASN B 1 81  ? 32.400  -3.869  -10.233  1.00 23.30  ? 74   ASN B OD1 1 
ATOM   4071  N ND2 . ASN B 1 81  ? 34.317  -4.549  -9.299   1.00 30.16  ? 74   ASN B ND2 1 
ATOM   4072  N N   . THR B 1 82  ? 30.228  -8.357  -8.230   1.00 23.28  ? 75   THR B N   1 
ATOM   4073  C CA  . THR B 1 82  ? 29.842  -9.790  -8.110   1.00 22.95  ? 75   THR B CA  1 
ATOM   4074  C C   . THR B 1 82  ? 28.371  -9.964  -7.728   1.00 21.12  ? 75   THR B C   1 
ATOM   4075  O O   . THR B 1 82  ? 27.783  -9.039  -7.136   1.00 19.17  ? 75   THR B O   1 
ATOM   4076  C CB  . THR B 1 82  ? 30.752  -10.547 -7.143   1.00 23.35  ? 75   THR B CB  1 
ATOM   4077  O OG1 . THR B 1 82  ? 30.620  -9.957  -5.851   1.00 24.92  ? 75   THR B OG1 1 
ATOM   4078  C CG2 . THR B 1 82  ? 32.198  -10.519 -7.570   1.00 24.77  ? 75   THR B CG2 1 
ATOM   4079  N N   . LEU B 1 83  ? 27.825  -11.122 -8.113   1.00 21.77  ? 76   LEU B N   1 
ATOM   4080  C CA  . LEU B 1 83  ? 26.452  -11.589 -7.787   1.00 23.54  ? 76   LEU B CA  1 
ATOM   4081  C C   . LEU B 1 83  ? 26.559  -12.914 -7.045   1.00 23.88  ? 76   LEU B C   1 
ATOM   4082  O O   . LEU B 1 83  ? 27.439  -13.731 -7.390   1.00 22.57  ? 76   LEU B O   1 
ATOM   4083  C CB  . LEU B 1 83  ? 25.634  -11.778 -9.065   1.00 24.23  ? 76   LEU B CB  1 
ATOM   4084  C CG  . LEU B 1 83  ? 25.267  -10.485 -9.779   1.00 24.66  ? 76   LEU B CG  1 
ATOM   4085  C CD1 . LEU B 1 83  ? 24.463  -10.783 -11.024  1.00 25.70  ? 76   LEU B CD1 1 
ATOM   4086  C CD2 . LEU B 1 83  ? 24.501  -9.566  -8.849   1.00 24.85  ? 76   LEU B CD2 1 
ATOM   4087  N N   . VAL B 1 84  ? 25.664  -13.120 -6.088   1.00 24.07  ? 77   VAL B N   1 
ATOM   4088  C CA  . VAL B 1 84  ? 25.625  -14.348 -5.258   1.00 25.10  ? 77   VAL B CA  1 
ATOM   4089  C C   . VAL B 1 84  ? 24.263  -15.014 -5.472   1.00 25.78  ? 77   VAL B C   1 
ATOM   4090  O O   . VAL B 1 84  ? 23.238  -14.315 -5.348   1.00 24.72  ? 77   VAL B O   1 
ATOM   4091  C CB  . VAL B 1 84  ? 25.876  -13.999 -3.786   1.00 27.16  ? 77   VAL B CB  1 
ATOM   4092  C CG1 . VAL B 1 84  ? 25.926  -15.257 -2.932   1.00 29.67  ? 77   VAL B CG1 1 
ATOM   4093  C CG2 . VAL B 1 84  ? 27.133  -13.162 -3.611   1.00 26.65  ? 77   VAL B CG2 1 
ATOM   4094  N N   . ASP B 1 85  ? 24.272  -16.303 -5.820   1.00 25.22  ? 78   ASP B N   1 
ATOM   4095  C CA  . ASP B 1 85  ? 23.047  -17.128 -5.975   1.00 25.19  ? 78   ASP B CA  1 
ATOM   4096  C C   . ASP B 1 85  ? 22.615  -17.640 -4.597   1.00 25.57  ? 78   ASP B C   1 
ATOM   4097  O O   . ASP B 1 85  ? 23.309  -17.362 -3.598   1.00 21.77  ? 78   ASP B O   1 
ATOM   4098  C CB  . ASP B 1 85  ? 23.205  -18.260 -7.005   1.00 26.51  ? 78   ASP B CB  1 
ATOM   4099  C CG  . ASP B 1 85  ? 24.057  -19.452 -6.599   1.00 27.25  ? 78   ASP B CG  1 
ATOM   4100  O OD1 . ASP B 1 85  ? 24.444  -19.523 -5.417   1.00 24.97  ? 78   ASP B OD1 1 
ATOM   4101  O OD2 . ASP B 1 85  ? 24.323  -20.321 -7.480   1.00 28.97  ? 78   ASP B OD2 1 
ATOM   4102  N N   . THR B 1 86  ? 21.492  -18.359 -4.589   1.00 25.76  ? 79   THR B N   1 
ATOM   4103  C CA  . THR B 1 86  ? 20.827  -18.929 -3.410   1.00 26.74  ? 79   THR B CA  1 
ATOM   4104  C C   . THR B 1 86  ? 21.714  -19.982 -2.739   1.00 29.97  ? 79   THR B C   1 
ATOM   4105  O O   . THR B 1 86  ? 21.450  -20.268 -1.540   1.00 32.57  ? 79   THR B O   1 
ATOM   4106  C CB  . THR B 1 86  ? 19.461  -19.498 -3.811   1.00 27.09  ? 79   THR B CB  1 
ATOM   4107  O OG1 . THR B 1 86  ? 19.669  -20.393 -4.910   1.00 25.39  ? 79   THR B OG1 1 
ATOM   4108  C CG2 . THR B 1 86  ? 18.465  -18.407 -4.160   1.00 26.36  ? 79   THR B CG2 1 
ATOM   4109  N N   . GLN B 1 87  ? 22.710  -20.535 -3.441   1.00 29.22  ? 80   GLN B N   1 
ATOM   4110  C CA  . GLN B 1 87  ? 23.625  -21.577 -2.904   1.00 32.94  ? 80   GLN B CA  1 
ATOM   4111  C C   . GLN B 1 87  ? 24.919  -20.937 -2.378   1.00 32.90  ? 80   GLN B C   1 
ATOM   4112  O O   . GLN B 1 87  ? 25.814  -21.699 -1.949   1.00 30.43  ? 80   GLN B O   1 
ATOM   4113  C CB  . GLN B 1 87  ? 23.947  -22.610 -3.979   1.00 35.94  ? 80   GLN B CB  1 
ATOM   4114  C CG  . GLN B 1 87  ? 22.703  -23.187 -4.627   1.00 40.68  ? 80   GLN B CG  1 
ATOM   4115  C CD  . GLN B 1 87  ? 23.036  -24.092 -5.786   1.00 46.79  ? 80   GLN B CD  1 
ATOM   4116  O OE1 . GLN B 1 87  ? 23.120  -23.669 -6.948   1.00 44.61  ? 80   GLN B OE1 1 
ATOM   4117  N NE2 . GLN B 1 87  ? 23.246  -25.356 -5.455   1.00 50.80  ? 80   GLN B NE2 1 
ATOM   4118  N N   . GLY B 1 88  ? 25.017  -19.603 -2.424   1.00 32.81  ? 81   GLY B N   1 
ATOM   4119  C CA  . GLY B 1 88  ? 26.179  -18.831 -1.941   1.00 34.31  ? 81   GLY B CA  1 
ATOM   4120  C C   . GLY B 1 88  ? 27.321  -18.747 -2.951   1.00 33.89  ? 81   GLY B C   1 
ATOM   4121  O O   . GLY B 1 88  ? 28.405  -18.247 -2.579   1.00 29.73  ? 81   GLY B O   1 
ATOM   4122  N N   . GLN B 1 89  ? 27.104  -19.201 -4.184   1.00 35.71  ? 82   GLN B N   1 
ATOM   4123  C CA  . GLN B 1 89  ? 28.139  -19.151 -5.242   1.00 38.45  ? 82   GLN B CA  1 
ATOM   4124  C C   . GLN B 1 89  ? 28.218  -17.712 -5.760   1.00 35.34  ? 82   GLN B C   1 
ATOM   4125  O O   . GLN B 1 89  ? 27.172  -17.152 -6.114   1.00 32.90  ? 82   GLN B O   1 
ATOM   4126  C CB  . GLN B 1 89  ? 27.869  -20.221 -6.304   1.00 45.01  ? 82   GLN B CB  1 
ATOM   4127  C CG  . GLN B 1 89  ? 28.154  -21.642 -5.812   1.00 54.23  ? 82   GLN B CG  1 
ATOM   4128  C CD  . GLN B 1 89  ? 29.615  -21.978 -5.544   1.00 72.40  ? 82   GLN B CD  1 
ATOM   4129  O OE1 . GLN B 1 89  ? 30.510  -21.742 -6.371   1.00 79.74  ? 82   GLN B OE1 1 
ATOM   4130  N NE2 . GLN B 1 89  ? 29.877  -22.584 -4.387   1.00 80.18  ? 82   GLN B NE2 1 
ATOM   4131  N N   . GLU B 1 90  ? 29.420  -17.122 -5.721   1.00 33.43  ? 83   GLU B N   1 
ATOM   4132  C CA  . GLU B 1 90  ? 29.692  -15.710 -6.110   1.00 32.76  ? 83   GLU B CA  1 
ATOM   4133  C C   . GLU B 1 90  ? 30.164  -15.710 -7.570   1.00 28.67  ? 83   GLU B C   1 
ATOM   4134  O O   . GLU B 1 90  ? 30.982  -16.534 -7.906   1.00 28.66  ? 83   GLU B O   1 
ATOM   4135  C CB  . GLU B 1 90  ? 30.700  -15.080 -5.136   1.00 33.38  ? 83   GLU B CB  1 
ATOM   4136  C CG  . GLU B 1 90  ? 30.819  -13.557 -5.246   1.00 35.84  ? 83   GLU B CG  1 
ATOM   4137  C CD  . GLU B 1 90  ? 31.735  -12.864 -4.243   1.00 38.31  ? 83   GLU B CD  1 
ATOM   4138  O OE1 . GLU B 1 90  ? 32.768  -13.452 -3.862   1.00 40.91  ? 83   GLU B OE1 1 
ATOM   4139  O OE2 . GLU B 1 90  ? 31.391  -11.765 -3.775   1.00 43.40  ? 83   GLU B OE2 1 
ATOM   4140  N N   . PHE B 1 91  ? 29.598  -14.848 -8.405   1.00 27.71  ? 84   PHE B N   1 
ATOM   4141  C CA  . PHE B 1 91  ? 29.904  -14.732 -9.847   1.00 26.40  ? 84   PHE B CA  1 
ATOM   4142  C C   . PHE B 1 91  ? 30.533  -13.374 -10.077  1.00 26.83  ? 84   PHE B C   1 
ATOM   4143  O O   . PHE B 1 91  ? 30.030  -12.402 -9.523   1.00 26.99  ? 84   PHE B O   1 
ATOM   4144  C CB  . PHE B 1 91  ? 28.646  -14.827 -10.709  1.00 27.81  ? 84   PHE B CB  1 
ATOM   4145  C CG  . PHE B 1 91  ? 28.009  -16.187 -10.691  1.00 27.63  ? 84   PHE B CG  1 
ATOM   4146  C CD1 . PHE B 1 91  ? 27.251  -16.601 -9.608   1.00 27.67  ? 84   PHE B CD1 1 
ATOM   4147  C CD2 . PHE B 1 91  ? 28.209  -17.068 -11.736  1.00 27.56  ? 84   PHE B CD2 1 
ATOM   4148  C CE1 . PHE B 1 91  ? 26.710  -17.874 -9.576   1.00 27.80  ? 84   PHE B CE1 1 
ATOM   4149  C CE2 . PHE B 1 91  ? 27.635  -18.327 -11.720  1.00 28.39  ? 84   PHE B CE2 1 
ATOM   4150  C CZ  . PHE B 1 91  ? 26.879  -18.723 -10.646  1.00 28.07  ? 84   PHE B CZ  1 
ATOM   4151  N N   . ILE B 1 92  ? 31.607  -13.321 -10.853  1.00 26.62  ? 85   ILE B N   1 
ATOM   4152  C CA  . ILE B 1 92  ? 32.097  -12.038 -11.415  1.00 26.82  ? 85   ILE B CA  1 
ATOM   4153  C C   . ILE B 1 92  ? 31.141  -11.692 -12.551  1.00 27.20  ? 85   ILE B C   1 
ATOM   4154  O O   . ILE B 1 92  ? 30.841  -12.595 -13.344  1.00 26.29  ? 85   ILE B O   1 
ATOM   4155  C CB  . ILE B 1 92  ? 33.567  -12.127 -11.853  1.00 27.98  ? 85   ILE B CB  1 
ATOM   4156  C CG1 . ILE B 1 92  ? 34.484  -12.296 -10.637  1.00 28.82  ? 85   ILE B CG1 1 
ATOM   4157  C CG2 . ILE B 1 92  ? 33.948  -10.903 -12.669  1.00 27.09  ? 85   ILE B CG2 1 
ATOM   4158  C CD1 . ILE B 1 92  ? 35.876  -12.788 -10.969  1.00 30.48  ? 85   ILE B CD1 1 
ATOM   4159  N N   . ASP B 1 93  ? 30.665  -10.445 -12.585  1.00 26.86  ? 86   ASP B N   1 
ATOM   4160  C CA  . ASP B 1 93  ? 29.628  -9.987  -13.536  1.00 25.26  ? 86   ASP B CA  1 
ATOM   4161  C C   . ASP B 1 93  ? 30.271  -9.331  -14.761  1.00 26.39  ? 86   ASP B C   1 
ATOM   4162  O O   . ASP B 1 93  ? 30.645  -8.155  -14.680  1.00 26.68  ? 86   ASP B O   1 
ATOM   4163  C CB  . ASP B 1 93  ? 28.638  -9.041  -12.864  1.00 24.28  ? 86   ASP B CB  1 
ATOM   4164  C CG  . ASP B 1 93  ? 27.438  -8.754  -13.747  1.00 24.03  ? 86   ASP B CG  1 
ATOM   4165  O OD1 . ASP B 1 93  ? 27.408  -9.263  -14.899  1.00 21.33  ? 86   ASP B OD1 1 
ATOM   4166  O OD2 . ASP B 1 93  ? 26.533  -8.050  -13.277  1.00 27.39  ? 86   ASP B OD2 1 
ATOM   4167  N N   . CYS B 1 94  ? 30.348  -10.070 -15.870  1.00 27.48  ? 87   CYS B N   1 
ATOM   4168  C CA  . CYS B 1 94  ? 30.758  -9.568  -17.208  1.00 28.12  ? 87   CYS B CA  1 
ATOM   4169  C C   . CYS B 1 94  ? 29.563  -9.416  -18.155  1.00 28.40  ? 87   CYS B C   1 
ATOM   4170  O O   . CYS B 1 94  ? 29.781  -9.116  -19.358  1.00 30.96  ? 87   CYS B O   1 
ATOM   4171  C CB  . CYS B 1 94  ? 31.765  -10.521 -17.826  1.00 28.25  ? 87   CYS B CB  1 
ATOM   4172  S SG  . CYS B 1 94  ? 33.343  -10.383 -16.968  1.00 29.29  ? 87   CYS B SG  1 
ATOM   4173  N N   . LEU B 1 95  ? 28.356  -9.669  -17.655  1.00 27.58  ? 88   LEU B N   1 
ATOM   4174  C CA  . LEU B 1 95  ? 27.096  -9.400  -18.377  1.00 27.25  ? 88   LEU B CA  1 
ATOM   4175  C C   . LEU B 1 95  ? 26.693  -7.940  -18.133  1.00 27.80  ? 88   LEU B C   1 
ATOM   4176  O O   . LEU B 1 95  ? 26.243  -7.271  -19.092  1.00 30.69  ? 88   LEU B O   1 
ATOM   4177  C CB  . LEU B 1 95  ? 26.054  -10.398 -17.882  1.00 28.92  ? 88   LEU B CB  1 
ATOM   4178  C CG  . LEU B 1 95  ? 24.704  -10.329 -18.600  1.00 33.56  ? 88   LEU B CG  1 
ATOM   4179  C CD1 . LEU B 1 95  ? 24.863  -10.273 -20.122  1.00 35.90  ? 88   LEU B CD1 1 
ATOM   4180  C CD2 . LEU B 1 95  ? 23.824  -11.509 -18.212  1.00 33.05  ? 88   LEU B CD2 1 
ATOM   4181  N N   . GLY B 1 96  ? 26.871  -7.459  -16.898  1.00 30.08  ? 89   GLY B N   1 
ATOM   4182  C CA  . GLY B 1 96  ? 26.527  -6.091  -16.453  1.00 30.42  ? 89   GLY B CA  1 
ATOM   4183  C C   . GLY B 1 96  ? 25.052  -5.783  -16.656  1.00 30.40  ? 89   GLY B C   1 
ATOM   4184  O O   . GLY B 1 96  ? 24.716  -4.600  -16.893  1.00 32.13  ? 89   GLY B O   1 
ATOM   4185  N N   . GLY B 1 97  ? 24.186  -6.795  -16.550  1.00 29.05  ? 90   GLY B N   1 
ATOM   4186  C CA  . GLY B 1 97  ? 22.759  -6.642  -16.879  1.00 30.45  ? 90   GLY B CA  1 
ATOM   4187  C C   . GLY B 1 97  ? 22.583  -5.995  -18.245  1.00 31.62  ? 90   GLY B C   1 
ATOM   4188  O O   . GLY B 1 97  ? 21.679  -5.164  -18.396  1.00 30.36  ? 90   GLY B O   1 
ATOM   4189  N N   . PHE B 1 98  ? 23.435  -6.334  -19.218  1.00 32.45  ? 91   PHE B N   1 
ATOM   4190  C CA  . PHE B 1 98  ? 23.330  -5.839  -20.612  1.00 33.55  ? 91   PHE B CA  1 
ATOM   4191  C C   . PHE B 1 98  ? 23.583  -4.322  -20.642  1.00 30.17  ? 91   PHE B C   1 
ATOM   4192  O O   . PHE B 1 98  ? 23.024  -3.635  -21.532  1.00 30.00  ? 91   PHE B O   1 
ATOM   4193  C CB  . PHE B 1 98  ? 21.969  -6.260  -21.188  1.00 37.88  ? 91   PHE B CB  1 
ATOM   4194  C CG  . PHE B 1 98  ? 21.768  -7.760  -21.268  1.00 42.84  ? 91   PHE B CG  1 
ATOM   4195  C CD1 . PHE B 1 98  ? 22.187  -8.477  -22.385  1.00 41.50  ? 91   PHE B CD1 1 
ATOM   4196  C CD2 . PHE B 1 98  ? 21.184  -8.469  -20.225  1.00 48.71  ? 91   PHE B CD2 1 
ATOM   4197  C CE1 . PHE B 1 98  ? 22.016  -9.853  -22.471  1.00 40.92  ? 91   PHE B CE1 1 
ATOM   4198  C CE2 . PHE B 1 98  ? 21.011  -9.848  -20.314  1.00 51.17  ? 91   PHE B CE2 1 
ATOM   4199  C CZ  . PHE B 1 98  ? 21.426  -10.540 -21.439  1.00 45.64  ? 91   PHE B CZ  1 
ATOM   4200  N N   . GLY B 1 99  ? 24.441  -3.829  -19.736  1.00 26.14  ? 92   GLY B N   1 
ATOM   4201  C CA  . GLY B 1 99  ? 24.944  -2.440  -19.738  1.00 24.39  ? 92   GLY B CA  1 
ATOM   4202  C C   . GLY B 1 99  ? 24.249  -1.546  -18.728  1.00 22.80  ? 92   GLY B C   1 
ATOM   4203  O O   . GLY B 1 99  ? 24.269  -0.320  -18.906  1.00 22.26  ? 92   GLY B O   1 
ATOM   4204  N N   . ILE B 1 100 ? 23.684  -2.134  -17.680  1.00 21.20  ? 93   ILE B N   1 
ATOM   4205  C CA  . ILE B 1 100 ? 22.979  -1.398  -16.592  1.00 21.92  ? 93   ILE B CA  1 
ATOM   4206  C C   . ILE B 1 100 ? 23.962  -1.019  -15.492  1.00 22.34  ? 93   ILE B C   1 
ATOM   4207  O O   . ILE B 1 100 ? 23.885  0.121   -15.004  1.00 22.60  ? 93   ILE B O   1 
ATOM   4208  C CB  . ILE B 1 100 ? 21.866  -2.272  -16.018  1.00 22.28  ? 93   ILE B CB  1 
ATOM   4209  C CG1 . ILE B 1 100 ? 20.832  -2.601  -17.094  1.00 24.25  ? 93   ILE B CG1 1 
ATOM   4210  C CG2 . ILE B 1 100 ? 21.234  -1.610  -14.814  1.00 23.03  ? 93   ILE B CG2 1 
ATOM   4211  C CD1 . ILE B 1 100 ? 19.897  -3.703  -16.679  1.00 26.73  ? 93   ILE B CD1 1 
ATOM   4212  N N   . PHE B 1 101 ? 24.811  -1.969  -15.093  1.00 23.13  ? 94   PHE B N   1 
ATOM   4213  C CA  . PHE B 1 101 ? 25.603  -1.932  -13.832  1.00 22.98  ? 94   PHE B CA  1 
ATOM   4214  C C   . PHE B 1 101 ? 26.955  -1.250  -14.083  1.00 21.10  ? 94   PHE B C   1 
ATOM   4215  O O   . PHE B 1 101 ? 27.987  -1.833  -13.719  1.00 19.59  ? 94   PHE B O   1 
ATOM   4216  C CB  . PHE B 1 101 ? 25.748  -3.348  -13.264  1.00 23.98  ? 94   PHE B CB  1 
ATOM   4217  C CG  . PHE B 1 101 ? 24.435  -3.993  -12.888  1.00 24.74  ? 94   PHE B CG  1 
ATOM   4218  C CD1 . PHE B 1 101 ? 23.640  -3.451  -11.887  1.00 24.34  ? 94   PHE B CD1 1 
ATOM   4219  C CD2 . PHE B 1 101 ? 23.979  -5.121  -13.561  1.00 26.12  ? 94   PHE B CD2 1 
ATOM   4220  C CE1 . PHE B 1 101 ? 22.426  -4.033  -11.556  1.00 25.49  ? 94   PHE B CE1 1 
ATOM   4221  C CE2 . PHE B 1 101 ? 22.761  -5.694  -13.238  1.00 26.71  ? 94   PHE B CE2 1 
ATOM   4222  C CZ  . PHE B 1 101 ? 21.989  -5.152  -12.230  1.00 26.12  ? 94   PHE B CZ  1 
ATOM   4223  N N   . ASN B 1 102 ? 26.932  -0.038  -14.659  1.00 19.14  ? 95   ASN B N   1 
ATOM   4224  C CA  . ASN B 1 102 ? 28.131  0.758   -15.023  1.00 17.98  ? 95   ASN B CA  1 
ATOM   4225  C C   . ASN B 1 102 ? 28.919  1.095   -13.758  1.00 17.87  ? 95   ASN B C   1 
ATOM   4226  O O   . ASN B 1 102 ? 30.162  1.037   -13.802  1.00 19.03  ? 95   ASN B O   1 
ATOM   4227  C CB  . ASN B 1 102 ? 27.759  2.022   -15.802  1.00 17.00  ? 95   ASN B CB  1 
ATOM   4228  C CG  . ASN B 1 102 ? 27.501  1.710   -17.262  1.00 15.90  ? 95   ASN B CG  1 
ATOM   4229  O OD1 . ASN B 1 102 ? 27.170  0.578   -17.599  1.00 16.24  ? 95   ASN B OD1 1 
ATOM   4230  N ND2 . ASN B 1 102 ? 27.643  2.701   -18.124  1.00 14.69  ? 95   ASN B ND2 1 
ATOM   4231  N N   . VAL B 1 103 ? 28.209  1.433   -12.687  1.00 17.11  ? 96   VAL B N   1 
ATOM   4232  C CA  . VAL B 1 103 ? 28.816  1.867   -11.400  1.00 16.78  ? 96   VAL B CA  1 
ATOM   4233  C C   . VAL B 1 103 ? 28.695  0.727   -10.379  1.00 16.23  ? 96   VAL B C   1 
ATOM   4234  O O   . VAL B 1 103 ? 28.819  0.998   -9.193   1.00 13.66  ? 96   VAL B O   1 
ATOM   4235  C CB  . VAL B 1 103 ? 28.213  3.198   -10.915  1.00 16.87  ? 96   VAL B CB  1 
ATOM   4236  C CG1 . VAL B 1 103 ? 28.462  4.322   -11.912  1.00 16.32  ? 96   VAL B CG1 1 
ATOM   4237  C CG2 . VAL B 1 103 ? 26.726  3.075   -10.612  1.00 17.77  ? 96   VAL B CG2 1 
ATOM   4238  N N   . GLY B 1 104 ? 28.527  -0.511  -10.857  1.00 17.03  ? 97   GLY B N   1 
ATOM   4239  C CA  . GLY B 1 104 ? 28.543  -1.722  -10.024  1.00 18.06  ? 97   GLY B CA  1 
ATOM   4240  C C   . GLY B 1 104 ? 27.189  -1.994  -9.369   1.00 19.48  ? 97   GLY B C   1 
ATOM   4241  O O   . GLY B 1 104 ? 26.210  -1.222  -9.608   1.00 16.73  ? 97   GLY B O   1 
ATOM   4242  N N   . HIS B 1 105 ? 27.152  -3.072  -8.575   1.00 21.18  ? 98   HIS B N   1 
ATOM   4243  C CA  . HIS B 1 105 ? 25.975  -3.592  -7.838   1.00 23.25  ? 98   HIS B CA  1 
ATOM   4244  C C   . HIS B 1 105 ? 25.894  -2.873  -6.487   1.00 24.38  ? 98   HIS B C   1 
ATOM   4245  O O   . HIS B 1 105 ? 26.899  -2.863  -5.760   1.00 25.32  ? 98   HIS B O   1 
ATOM   4246  C CB  . HIS B 1 105 ? 26.059  -5.123  -7.698   1.00 23.84  ? 98   HIS B CB  1 
ATOM   4247  C CG  . HIS B 1 105 ? 25.870  -5.848  -8.987   1.00 23.56  ? 98   HIS B CG  1 
ATOM   4248  N ND1 . HIS B 1 105 ? 24.617  -6.116  -9.511   1.00 25.20  ? 98   HIS B ND1 1 
ATOM   4249  C CD2 . HIS B 1 105 ? 26.755  -6.341  -9.877   1.00 23.86  ? 98   HIS B CD2 1 
ATOM   4250  C CE1 . HIS B 1 105 ? 24.742  -6.745  -10.671  1.00 23.45  ? 98   HIS B CE1 1 
ATOM   4251  N NE2 . HIS B 1 105 ? 26.037  -6.906  -10.907  1.00 24.22  ? 98   HIS B NE2 1 
ATOM   4252  N N   . ARG B 1 106 ? 24.733  -2.283  -6.185   1.00 25.65  ? 99   ARG B N   1 
ATOM   4253  C CA  . ARG B 1 106 ? 24.464  -1.525  -4.941   1.00 25.59  ? 99   ARG B CA  1 
ATOM   4254  C C   . ARG B 1 106 ? 25.621  -0.542  -4.722   1.00 26.05  ? 99   ARG B C   1 
ATOM   4255  O O   . ARG B 1 106 ? 26.316  -0.614  -3.685   1.00 22.29  ? 99   ARG B O   1 
ATOM   4256  C CB  . ARG B 1 106 ? 24.314  -2.489  -3.759   1.00 27.34  ? 99   ARG B CB  1 
ATOM   4257  C CG  . ARG B 1 106 ? 23.232  -3.544  -3.923   1.00 26.85  ? 99   ARG B CG  1 
ATOM   4258  C CD  . ARG B 1 106 ? 22.949  -4.270  -2.633   1.00 27.95  ? 99   ARG B CD  1 
ATOM   4259  N NE  . ARG B 1 106 ? 22.402  -3.381  -1.607   1.00 29.98  ? 99   ARG B NE  1 
ATOM   4260  C CZ  . ARG B 1 106 ? 23.068  -2.938  -0.543   1.00 29.57  ? 99   ARG B CZ  1 
ATOM   4261  N NH1 . ARG B 1 106 ? 24.319  -3.301  -0.351   1.00 29.36  ? 99   ARG B NH1 1 
ATOM   4262  N NH2 . ARG B 1 106 ? 22.479  -2.152  0.342    1.00 28.48  ? 99   ARG B NH2 1 
ATOM   4263  N N   . ASN B 1 107 ? 25.870  0.316   -5.705   1.00 25.91  ? 100  ASN B N   1 
ATOM   4264  C CA  . ASN B 1 107 ? 26.860  1.399   -5.525   1.00 24.22  ? 100  ASN B CA  1 
ATOM   4265  C C   . ASN B 1 107 ? 26.394  2.208   -4.322   1.00 23.16  ? 100  ASN B C   1 
ATOM   4266  O O   . ASN B 1 107 ? 25.282  2.724   -4.297   1.00 21.65  ? 100  ASN B O   1 
ATOM   4267  C CB  . ASN B 1 107 ? 27.035  2.245   -6.778   1.00 24.84  ? 100  ASN B CB  1 
ATOM   4268  C CG  . ASN B 1 107 ? 28.104  3.283   -6.569   1.00 25.04  ? 100  ASN B CG  1 
ATOM   4269  O OD1 . ASN B 1 107 ? 27.911  4.176   -5.763   1.00 25.07  ? 100  ASN B OD1 1 
ATOM   4270  N ND2 . ASN B 1 107 ? 29.224  3.172   -7.267   1.00 25.88  ? 100  ASN B ND2 1 
ATOM   4271  N N   . PRO B 1 108 ? 27.214  2.311   -3.267   1.00 22.11  ? 101  PRO B N   1 
ATOM   4272  C CA  . PRO B 1 108 ? 26.746  2.876   -2.009   1.00 22.77  ? 101  PRO B CA  1 
ATOM   4273  C C   . PRO B 1 108 ? 26.233  4.311   -2.195   1.00 22.28  ? 101  PRO B C   1 
ATOM   4274  O O   . PRO B 1 108 ? 25.334  4.699   -1.456   1.00 23.19  ? 101  PRO B O   1 
ATOM   4275  C CB  . PRO B 1 108 ? 27.981  2.830   -1.084   1.00 23.15  ? 101  PRO B CB  1 
ATOM   4276  C CG  . PRO B 1 108 ? 28.928  1.825   -1.733   1.00 22.85  ? 101  PRO B CG  1 
ATOM   4277  C CD  . PRO B 1 108 ? 28.625  1.890   -3.216   1.00 23.11  ? 101  PRO B CD  1 
ATOM   4278  N N   . VAL B 1 109 ? 26.824  5.073   -3.121   1.00 19.53  ? 102  VAL B N   1 
ATOM   4279  C CA  . VAL B 1 109 ? 26.415  6.486   -3.373   1.00 20.02  ? 102  VAL B CA  1 
ATOM   4280  C C   . VAL B 1 109 ? 25.006  6.500   -3.986   1.00 20.04  ? 102  VAL B C   1 
ATOM   4281  O O   . VAL B 1 109 ? 24.190  7.371   -3.601   1.00 22.00  ? 102  VAL B O   1 
ATOM   4282  C CB  . VAL B 1 109 ? 27.423  7.217   -4.267   1.00 19.46  ? 102  VAL B CB  1 
ATOM   4283  C CG1 . VAL B 1 109 ? 26.890  8.561   -4.745   1.00 18.69  ? 102  VAL B CG1 1 
ATOM   4284  C CG2 . VAL B 1 109 ? 28.767  7.376   -3.559   1.00 20.59  ? 102  VAL B CG2 1 
ATOM   4285  N N   . VAL B 1 110 ? 24.728  5.569   -4.894   1.00 19.25  ? 103  VAL B N   1 
ATOM   4286  C CA  . VAL B 1 110 ? 23.406  5.482   -5.567   1.00 20.68  ? 103  VAL B CA  1 
ATOM   4287  C C   . VAL B 1 110 ? 22.412  4.952   -4.532   1.00 20.95  ? 103  VAL B C   1 
ATOM   4288  O O   . VAL B 1 110 ? 21.338  5.573   -4.349   1.00 22.97  ? 103  VAL B O   1 
ATOM   4289  C CB  . VAL B 1 110 ? 23.432  4.613   -6.845   1.00 21.41  ? 103  VAL B CB  1 
ATOM   4290  C CG1 . VAL B 1 110 ? 22.063  4.562   -7.516   1.00 22.02  ? 103  VAL B CG1 1 
ATOM   4291  C CG2 . VAL B 1 110 ? 24.470  5.100   -7.840   1.00 20.86  ? 103  VAL B CG2 1 
ATOM   4292  N N   . VAL B 1 111 ? 22.761  3.856   -3.864   1.00 19.96  ? 104  VAL B N   1 
ATOM   4293  C CA  . VAL B 1 111 ? 21.852  3.233   -2.873   1.00 19.34  ? 104  VAL B CA  1 
ATOM   4294  C C   . VAL B 1 111 ? 21.480  4.322   -1.874   1.00 19.88  ? 104  VAL B C   1 
ATOM   4295  O O   . VAL B 1 111 ? 20.280  4.465   -1.592   1.00 20.13  ? 104  VAL B O   1 
ATOM   4296  C CB  . VAL B 1 111 ? 22.494  1.998   -2.232   1.00 19.53  ? 104  VAL B CB  1 
ATOM   4297  C CG1 . VAL B 1 111 ? 21.758  1.541   -0.989   1.00 20.08  ? 104  VAL B CG1 1 
ATOM   4298  C CG2 . VAL B 1 111 ? 22.588  0.873   -3.254   1.00 19.92  ? 104  VAL B CG2 1 
ATOM   4299  N N   . SER B 1 112 ? 22.457  5.113   -1.442   1.00 19.40  ? 105  SER B N   1 
ATOM   4300  C CA  . SER B 1 112 ? 22.266  6.195   -0.443   1.00 19.75  ? 105  SER B CA  1 
ATOM   4301  C C   . SER B 1 112 ? 21.229  7.207   -0.931   1.00 19.06  ? 105  SER B C   1 
ATOM   4302  O O   . SER B 1 112 ? 20.357  7.574   -0.161   1.00 18.74  ? 105  SER B O   1 
ATOM   4303  C CB  . SER B 1 112 ? 23.553  6.891   -0.123   1.00 20.08  ? 105  SER B CB  1 
ATOM   4304  O OG  . SER B 1 112 ? 23.310  8.032   0.702    1.00 19.96  ? 105  SER B OG  1 
ATOM   4305  N N   . ALA B 1 113 ? 21.367  7.681   -2.161   1.00 20.16  ? 106  ALA B N   1 
ATOM   4306  C CA  . ALA B 1 113 ? 20.497  8.738   -2.710   1.00 19.54  ? 106  ALA B CA  1 
ATOM   4307  C C   . ALA B 1 113 ? 19.060  8.222   -2.759   1.00 19.65  ? 106  ALA B C   1 
ATOM   4308  O O   . ALA B 1 113 ? 18.129  8.956   -2.353   1.00 18.83  ? 106  ALA B O   1 
ATOM   4309  C CB  . ALA B 1 113 ? 21.019  9.135   -4.059   1.00 19.99  ? 106  ALA B CB  1 
ATOM   4310  N N   . VAL B 1 114 ? 18.899  6.976   -3.190   1.00 20.78  ? 107  VAL B N   1 
ATOM   4311  C CA  . VAL B 1 114 ? 17.561  6.325   -3.331   1.00 21.22  ? 107  VAL B CA  1 
ATOM   4312  C C   . VAL B 1 114 ? 16.948  6.166   -1.930   1.00 20.81  ? 107  VAL B C   1 
ATOM   4313  O O   . VAL B 1 114 ? 15.812  6.625   -1.722   1.00 21.86  ? 107  VAL B O   1 
ATOM   4314  C CB  . VAL B 1 114 ? 17.695  4.997   -4.108   1.00 21.82  ? 107  VAL B CB  1 
ATOM   4315  C CG1 . VAL B 1 114 ? 16.460  4.109   -4.015   1.00 21.50  ? 107  VAL B CG1 1 
ATOM   4316  C CG2 . VAL B 1 114 ? 18.085  5.253   -5.554   1.00 22.62  ? 107  VAL B CG2 1 
ATOM   4317  N N   A GLN B 1 115 ? 17.684  5.548   -0.998   0.55 20.61  ? 108  GLN B N   1 
ATOM   4318  N N   B GLN B 1 115 ? 17.685  5.551   -0.999   0.45 21.20  ? 108  GLN B N   1 
ATOM   4319  C CA  A GLN B 1 115 ? 17.284  5.382   0.427    0.55 20.64  ? 108  GLN B CA  1 
ATOM   4320  C CA  B GLN B 1 115 ? 17.281  5.382   0.423    0.45 21.53  ? 108  GLN B CA  1 
ATOM   4321  C C   A GLN B 1 115 ? 16.796  6.723   0.982    0.55 19.99  ? 108  GLN B C   1 
ATOM   4322  C C   B GLN B 1 115 ? 16.799  6.723   0.985    0.45 20.56  ? 108  GLN B C   1 
ATOM   4323  O O   A GLN B 1 115 ? 15.738  6.738   1.633    0.55 18.99  ? 108  GLN B O   1 
ATOM   4324  O O   B GLN B 1 115 ? 15.739  6.739   1.634    0.45 19.64  ? 108  GLN B O   1 
ATOM   4325  C CB  A GLN B 1 115 ? 18.459  4.909   1.279    0.55 21.46  ? 108  GLN B CB  1 
ATOM   4326  C CB  B GLN B 1 115 ? 18.456  4.869   1.252    0.45 22.96  ? 108  GLN B CB  1 
ATOM   4327  C CG  A GLN B 1 115 ? 18.692  3.410   1.264    0.55 22.46  ? 108  GLN B CG  1 
ATOM   4328  C CG  B GLN B 1 115 ? 18.093  4.546   2.693    0.45 24.74  ? 108  GLN B CG  1 
ATOM   4329  C CD  A GLN B 1 115 ? 19.871  3.050   2.142    0.55 23.93  ? 108  GLN B CD  1 
ATOM   4330  C CD  B GLN B 1 115 ? 17.187  3.344   2.823    0.45 26.32  ? 108  GLN B CD  1 
ATOM   4331  O OE1 A GLN B 1 115 ? 20.789  3.843   2.362    0.55 24.37  ? 108  GLN B OE1 1 
ATOM   4332  O OE1 B GLN B 1 115 ? 16.017  3.459   3.197    0.45 26.56  ? 108  GLN B OE1 1 
ATOM   4333  N NE2 A GLN B 1 115 ? 19.902  1.807   2.587    0.55 24.57  ? 108  GLN B NE2 1 
ATOM   4334  N NE2 B GLN B 1 115 ? 17.727  2.173   2.515    0.45 26.81  ? 108  GLN B NE2 1 
ATOM   4335  N N   . ASN B 1 116 ? 17.557  7.794   0.734    1.00 20.02  ? 109  ASN B N   1 
ATOM   4336  C CA  . ASN B 1 116 ? 17.278  9.155   1.267    1.00 20.95  ? 109  ASN B CA  1 
ATOM   4337  C C   . ASN B 1 116 ? 15.964  9.686   0.693    1.00 20.65  ? 109  ASN B C   1 
ATOM   4338  O O   . ASN B 1 116 ? 15.142  10.216  1.470    1.00 22.80  ? 109  ASN B O   1 
ATOM   4339  C CB  . ASN B 1 116 ? 18.412  10.140  0.982    1.00 22.14  ? 109  ASN B CB  1 
ATOM   4340  C CG  . ASN B 1 116 ? 19.537  10.082  1.991    1.00 23.32  ? 109  ASN B CG  1 
ATOM   4341  O OD1 . ASN B 1 116 ? 19.315  9.887   3.185    1.00 24.62  ? 109  ASN B OD1 1 
ATOM   4342  N ND2 . ASN B 1 116 ? 20.752  10.275  1.514    1.00 23.60  ? 109  ASN B ND2 1 
ATOM   4343  N N   . GLN B 1 117 ? 15.756  9.534   -0.610   1.00 20.82  ? 110  GLN B N   1 
ATOM   4344  C CA  . GLN B 1 117 ? 14.533  10.037  -1.292   1.00 19.95  ? 110  GLN B CA  1 
ATOM   4345  C C   . GLN B 1 117 ? 13.334  9.163   -0.903   1.00 18.82  ? 110  GLN B C   1 
ATOM   4346  O O   . GLN B 1 117 ? 12.259  9.718   -0.690   1.00 19.16  ? 110  GLN B O   1 
ATOM   4347  C CB  . GLN B 1 117 ? 14.742  10.090  -2.802   1.00 20.81  ? 110  GLN B CB  1 
ATOM   4348  C CG  . GLN B 1 117 ? 13.690  10.924  -3.515   1.00 22.48  ? 110  GLN B CG  1 
ATOM   4349  C CD  . GLN B 1 117 ? 13.535  12.302  -2.915   1.00 23.68  ? 110  GLN B CD  1 
ATOM   4350  O OE1 . GLN B 1 117 ? 14.527  12.968  -2.566   1.00 21.30  ? 110  GLN B OE1 1 
ATOM   4351  N NE2 . GLN B 1 117 ? 12.280  12.737  -2.806   1.00 23.64  ? 110  GLN B NE2 1 
ATOM   4352  N N   . LEU B 1 118 ? 13.523  7.852   -0.775   1.00 18.75  ? 111  LEU B N   1 
ATOM   4353  C CA  . LEU B 1 118 ? 12.478  6.909   -0.306   1.00 19.07  ? 111  LEU B CA  1 
ATOM   4354  C C   . LEU B 1 118 ? 11.928  7.394   1.046    1.00 20.33  ? 111  LEU B C   1 
ATOM   4355  O O   . LEU B 1 118 ? 10.722  7.253   1.270    1.00 20.25  ? 111  LEU B O   1 
ATOM   4356  C CB  . LEU B 1 118 ? 13.072  5.501   -0.212   1.00 18.83  ? 111  LEU B CB  1 
ATOM   4357  C CG  . LEU B 1 118 ? 12.123  4.391   0.252    1.00 19.21  ? 111  LEU B CG  1 
ATOM   4358  C CD1 . LEU B 1 118 ? 10.861  4.343   -0.593   1.00 18.73  ? 111  LEU B CD1 1 
ATOM   4359  C CD2 . LEU B 1 118 ? 12.805  3.034   0.225    1.00 19.44  ? 111  LEU B CD2 1 
ATOM   4360  N N   . ALA B 1 119 ? 12.765  7.980   1.903    1.00 21.72  ? 112  ALA B N   1 
ATOM   4361  C CA  . ALA B 1 119 ? 12.358  8.474   3.238    1.00 22.32  ? 112  ALA B CA  1 
ATOM   4362  C C   . ALA B 1 119 ? 11.476  9.727   3.122    1.00 23.85  ? 112  ALA B C   1 
ATOM   4363  O O   . ALA B 1 119 ? 10.757  10.004  4.106    1.00 27.57  ? 112  ALA B O   1 
ATOM   4364  C CB  . ALA B 1 119 ? 13.574  8.740   4.085    1.00 21.82  ? 112  ALA B CB  1 
ATOM   4365  N N   . LYS B 1 120 ? 11.505  10.452  1.994    1.00 25.35  ? 113  LYS B N   1 
ATOM   4366  C CA  . LYS B 1 120 ? 10.718  11.703  1.787    1.00 26.49  ? 113  LYS B CA  1 
ATOM   4367  C C   . LYS B 1 120 ? 9.507   11.476  0.876    1.00 26.84  ? 113  LYS B C   1 
ATOM   4368  O O   . LYS B 1 120 ? 8.368   11.749  1.327    1.00 25.50  ? 113  LYS B O   1 
ATOM   4369  C CB  . LYS B 1 120 ? 11.569  12.780  1.126    1.00 27.93  ? 113  LYS B CB  1 
ATOM   4370  C CG  . LYS B 1 120 ? 12.573  13.449  2.035    1.00 30.12  ? 113  LYS B CG  1 
ATOM   4371  C CD  . LYS B 1 120 ? 13.153  14.683  1.397    1.00 31.13  ? 113  LYS B CD  1 
ATOM   4372  C CE  . LYS B 1 120 ? 14.545  14.444  0.874    1.00 32.18  ? 113  LYS B CE  1 
ATOM   4373  N NZ  . LYS B 1 120 ? 14.975  15.506  -0.068   1.00 34.10  ? 113  LYS B NZ  1 
ATOM   4374  N N   . GLN B 1 121 ? 9.754   11.074  -0.376   1.00 27.58  ? 114  GLN B N   1 
ATOM   4375  C CA  . GLN B 1 121 ? 8.725   10.947  -1.446   1.00 29.04  ? 114  GLN B CA  1 
ATOM   4376  C C   . GLN B 1 121 ? 9.277   10.094  -2.591   1.00 27.76  ? 114  GLN B C   1 
ATOM   4377  O O   . GLN B 1 121 ? 10.064  10.589  -3.401   1.00 26.27  ? 114  GLN B O   1 
ATOM   4378  C CB  . GLN B 1 121 ? 8.322   12.330  -1.960   1.00 31.50  ? 114  GLN B CB  1 
ATOM   4379  C CG  . GLN B 1 121 ? 6.914   12.353  -2.518   1.00 34.66  ? 114  GLN B CG  1 
ATOM   4380  C CD  . GLN B 1 121 ? 6.661   13.474  -3.493   1.00 40.54  ? 114  GLN B CD  1 
ATOM   4381  O OE1 . GLN B 1 121 ? 7.577   14.132  -3.980   1.00 44.43  ? 114  GLN B OE1 1 
ATOM   4382  N NE2 . GLN B 1 121 ? 5.386   13.679  -3.798   1.00 46.58  ? 114  GLN B NE2 1 
ATOM   4383  N N   . PRO B 1 122 ? 8.916   8.788   -2.676   1.00 26.02  ? 115  PRO B N   1 
ATOM   4384  C CA  . PRO B 1 122 ? 9.438   7.920   -3.732   1.00 25.41  ? 115  PRO B CA  1 
ATOM   4385  C C   . PRO B 1 122 ? 8.782   8.151   -5.103   1.00 25.11  ? 115  PRO B C   1 
ATOM   4386  O O   . PRO B 1 122 ? 9.522   8.200   -6.109   1.00 26.88  ? 115  PRO B O   1 
ATOM   4387  C CB  . PRO B 1 122 ? 9.149   6.508   -3.200   1.00 24.96  ? 115  PRO B CB  1 
ATOM   4388  C CG  . PRO B 1 122 ? 7.926   6.674   -2.319   1.00 23.94  ? 115  PRO B CG  1 
ATOM   4389  C CD  . PRO B 1 122 ? 8.020   8.075   -1.750   1.00 24.36  ? 115  PRO B CD  1 
ATOM   4390  N N   . LEU B 1 123 ? 7.450   8.279   -5.143   1.00 24.71  ? 116  LEU B N   1 
ATOM   4391  C CA  . LEU B 1 123 ? 6.697   8.652   -6.373   1.00 25.32  ? 116  LEU B CA  1 
ATOM   4392  C C   . LEU B 1 123 ? 5.988   9.983   -6.151   1.00 26.08  ? 116  LEU B C   1 
ATOM   4393  O O   . LEU B 1 123 ? 5.561   10.260  -4.997   1.00 32.10  ? 116  LEU B O   1 
ATOM   4394  C CB  . LEU B 1 123 ? 5.704   7.554   -6.748   1.00 23.48  ? 116  LEU B CB  1 
ATOM   4395  C CG  . LEU B 1 123 ? 6.331   6.218   -7.136   1.00 23.30  ? 116  LEU B CG  1 
ATOM   4396  C CD1 . LEU B 1 123 ? 5.265   5.280   -7.695   1.00 22.39  ? 116  LEU B CD1 1 
ATOM   4397  C CD2 . LEU B 1 123 ? 7.486   6.389   -8.133   1.00 22.29  ? 116  LEU B CD2 1 
ATOM   4398  N N   . HIS B 1 124 ? 5.865   10.743  -7.234   1.00 26.56  ? 117  HIS B N   1 
ATOM   4399  C CA  . HIS B 1 124 ? 5.361   12.137  -7.263   1.00 29.54  ? 117  HIS B CA  1 
ATOM   4400  C C   . HIS B 1 124 ? 3.862   12.142  -7.625   1.00 32.35  ? 117  HIS B C   1 
ATOM   4401  O O   . HIS B 1 124 ? 3.318   11.078  -8.060   1.00 31.13  ? 117  HIS B O   1 
ATOM   4402  C CB  . HIS B 1 124 ? 6.229   13.005  -8.198   1.00 28.26  ? 117  HIS B CB  1 
ATOM   4403  C CG  . HIS B 1 124 ? 6.211   12.553  -9.614   1.00 28.62  ? 117  HIS B CG  1 
ATOM   4404  N ND1 . HIS B 1 124 ? 6.618   11.284  -9.991   1.00 29.65  ? 117  HIS B ND1 1 
ATOM   4405  C CD2 . HIS B 1 124 ? 5.837   13.180  -10.746  1.00 32.20  ? 117  HIS B CD2 1 
ATOM   4406  C CE1 . HIS B 1 124 ? 6.498   11.149  -11.294  1.00 32.79  ? 117  HIS B CE1 1 
ATOM   4407  N NE2 . HIS B 1 124 ? 6.002   12.294  -11.787  1.00 34.23  ? 117  HIS B NE2 1 
ATOM   4408  N N   . SER B 1 125 ? 3.223   13.303  -7.435   1.00 34.37  ? 118  SER B N   1 
ATOM   4409  C CA  . SER B 1 125 ? 1.774   13.555  -7.639   1.00 35.77  ? 118  SER B CA  1 
ATOM   4410  C C   . SER B 1 125 ? 1.485   13.721  -9.132   1.00 39.12  ? 118  SER B C   1 
ATOM   4411  O O   . SER B 1 125 ? 0.372   13.358  -9.570   1.00 38.99  ? 118  SER B O   1 
ATOM   4412  C CB  . SER B 1 125 ? 1.339   14.785  -6.889   1.00 33.46  ? 118  SER B CB  1 
ATOM   4413  O OG  . SER B 1 125 ? 2.046   15.929  -7.350   1.00 33.40  ? 118  SER B OG  1 
ATOM   4414  N N   . GLN B 1 126 ? 2.458   14.282  -9.858   1.00 42.23  ? 119  GLN B N   1 
ATOM   4415  C CA  . GLN B 1 126 ? 2.356   14.718  -11.272  1.00 43.98  ? 119  GLN B CA  1 
ATOM   4416  C C   . GLN B 1 126 ? 1.530   16.007  -11.380  1.00 46.30  ? 119  GLN B C   1 
ATOM   4417  O O   . GLN B 1 126 ? 1.128   16.347  -12.503  1.00 61.14  ? 119  GLN B O   1 
ATOM   4418  C CB  . GLN B 1 126 ? 1.724   13.628  -12.135  1.00 46.73  ? 119  GLN B CB  1 
ATOM   4419  C CG  . GLN B 1 126 ? 2.628   12.439  -12.399  1.00 47.27  ? 119  GLN B CG  1 
ATOM   4420  C CD  . GLN B 1 126 ? 1.822   11.170  -12.348  1.00 46.87  ? 119  GLN B CD  1 
ATOM   4421  O OE1 . GLN B 1 126 ? 1.895   10.439  -11.374  1.00 50.34  ? 119  GLN B OE1 1 
ATOM   4422  N NE2 . GLN B 1 126 ? 0.998   10.942  -13.357  1.00 45.58  ? 119  GLN B NE2 1 
ATOM   4423  N N   . GLU B 1 127 ? 1.297   16.729  -10.287  1.00 42.83  ? 120  GLU B N   1 
ATOM   4424  C CA  . GLU B 1 127 ? 0.618   18.047  -10.349  1.00 42.99  ? 120  GLU B CA  1 
ATOM   4425  C C   . GLU B 1 127 ? 1.532   19.119  -9.761   1.00 40.64  ? 120  GLU B C   1 
ATOM   4426  O O   . GLU B 1 127 ? 1.694   20.152  -10.400  1.00 41.85  ? 120  GLU B O   1 
ATOM   4427  C CB  . GLU B 1 127 ? -0.720  18.011  -9.612   1.00 49.24  ? 120  GLU B CB  1 
ATOM   4428  C CG  . GLU B 1 127 ? -1.613  19.211  -9.898   1.00 50.24  ? 120  GLU B CG  1 
ATOM   4429  C CD  . GLU B 1 127 ? -2.204  19.285  -11.299  1.00 47.48  ? 120  GLU B CD  1 
ATOM   4430  O OE1 . GLU B 1 127 ? -2.088  18.291  -12.060  1.00 45.45  ? 120  GLU B OE1 1 
ATOM   4431  O OE2 . GLU B 1 127 ? -2.779  20.344  -11.624  1.00 49.73  ? 120  GLU B OE2 1 
ATOM   4432  N N   . LEU B 1 128 ? 2.088   18.902  -8.575   1.00 39.85  ? 121  LEU B N   1 
ATOM   4433  C CA  . LEU B 1 128 ? 3.100   19.830  -8.005   1.00 42.44  ? 121  LEU B CA  1 
ATOM   4434  C C   . LEU B 1 128 ? 4.404   19.668  -8.797   1.00 44.90  ? 121  LEU B C   1 
ATOM   4435  O O   . LEU B 1 128 ? 4.679   18.551  -9.281   1.00 47.59  ? 121  LEU B O   1 
ATOM   4436  C CB  . LEU B 1 128 ? 3.308   19.564  -6.512   1.00 40.77  ? 121  LEU B CB  1 
ATOM   4437  C CG  . LEU B 1 128 ? 2.319   20.286  -5.598   1.00 39.62  ? 121  LEU B CG  1 
ATOM   4438  C CD1 . LEU B 1 128 ? 0.926   19.721  -5.790   1.00 38.65  ? 121  LEU B CD1 1 
ATOM   4439  C CD2 . LEU B 1 128 ? 2.726   20.197  -4.132   1.00 40.36  ? 121  LEU B CD2 1 
ATOM   4440  N N   . LEU B 1 129 ? 5.165   20.755  -8.940   1.00 42.30  ? 122  LEU B N   1 
ATOM   4441  C CA  . LEU B 1 129 ? 6.532   20.728  -9.507   1.00 40.44  ? 122  LEU B CA  1 
ATOM   4442  C C   . LEU B 1 129 ? 7.356   19.746  -8.674   1.00 40.16  ? 122  LEU B C   1 
ATOM   4443  O O   . LEU B 1 129 ? 7.431   19.952  -7.464   1.00 40.27  ? 122  LEU B O   1 
ATOM   4444  C CB  . LEU B 1 129 ? 7.137   22.135  -9.450   1.00 39.42  ? 122  LEU B CB  1 
ATOM   4445  C CG  . LEU B 1 129 ? 6.354   23.246  -10.150  1.00 39.08  ? 122  LEU B CG  1 
ATOM   4446  C CD1 . LEU B 1 129 ? 7.114   24.565  -10.063  1.00 38.49  ? 122  LEU B CD1 1 
ATOM   4447  C CD2 . LEU B 1 129 ? 6.062   22.885  -11.604  1.00 39.94  ? 122  LEU B CD2 1 
ATOM   4448  N N   . ASP B 1 130 ? 7.905   18.695  -9.279   1.00 40.62  ? 123  ASP B N   1 
ATOM   4449  C CA  . ASP B 1 130 ? 8.827   17.773  -8.564   1.00 42.70  ? 123  ASP B CA  1 
ATOM   4450  C C   . ASP B 1 130 ? 10.256  18.262  -8.798   1.00 40.58  ? 123  ASP B C   1 
ATOM   4451  O O   . ASP B 1 130 ? 10.732  18.340  -9.928   1.00 42.94  ? 123  ASP B O   1 
ATOM   4452  C CB  . ASP B 1 130 ? 8.583   16.303  -8.919   1.00 43.45  ? 123  ASP B CB  1 
ATOM   4453  C CG  . ASP B 1 130 ? 8.482   16.000  -10.402  1.00 42.65  ? 123  ASP B CG  1 
ATOM   4454  O OD1 . ASP B 1 130 ? 7.950   16.855  -11.167  1.00 41.17  ? 123  ASP B OD1 1 
ATOM   4455  O OD2 . ASP B 1 130 ? 8.914   14.893  -10.774  1.00 44.45  ? 123  ASP B OD2 1 
ATOM   4456  N N   . PRO B 1 131 ? 10.995  18.577  -7.718   1.00 38.33  ? 124  PRO B N   1 
ATOM   4457  C CA  . PRO B 1 131 ? 12.268  19.282  -7.827   1.00 38.33  ? 124  PRO B CA  1 
ATOM   4458  C C   . PRO B 1 131 ? 13.434  18.452  -8.387   1.00 36.79  ? 124  PRO B C   1 
ATOM   4459  O O   . PRO B 1 131 ? 14.289  19.047  -9.008   1.00 40.57  ? 124  PRO B O   1 
ATOM   4460  C CB  . PRO B 1 131 ? 12.566  19.669  -6.371   1.00 38.22  ? 124  PRO B CB  1 
ATOM   4461  C CG  . PRO B 1 131 ? 11.923  18.558  -5.562   1.00 38.15  ? 124  PRO B CG  1 
ATOM   4462  C CD  . PRO B 1 131 ? 10.660  18.224  -6.329   1.00 39.55  ? 124  PRO B CD  1 
ATOM   4463  N N   . LEU B 1 132 ? 13.457  17.132  -8.178   1.00 32.72  ? 125  LEU B N   1 
ATOM   4464  C CA  . LEU B 1 132 ? 14.540  16.270  -8.715   1.00 31.75  ? 125  LEU B CA  1 
ATOM   4465  C C   . LEU B 1 132 ? 14.460  16.212  -10.243  1.00 32.05  ? 125  LEU B C   1 
ATOM   4466  O O   . LEU B 1 132 ? 15.531  16.077  -10.852  1.00 33.13  ? 125  LEU B O   1 
ATOM   4467  C CB  . LEU B 1 132 ? 14.443  14.868  -8.119   1.00 30.87  ? 125  LEU B CB  1 
ATOM   4468  C CG  . LEU B 1 132 ? 14.686  14.798  -6.616   1.00 33.11  ? 125  LEU B CG  1 
ATOM   4469  C CD1 . LEU B 1 132 ? 14.950  13.363  -6.190   1.00 33.63  ? 125  LEU B CD1 1 
ATOM   4470  C CD2 . LEU B 1 132 ? 15.838  15.702  -6.190   1.00 34.16  ? 125  LEU B CD2 1 
ATOM   4471  N N   . ARG B 1 133 ? 13.253  16.269  -10.825  1.00 29.87  ? 126  ARG B N   1 
ATOM   4472  C CA  . ARG B 1 133 ? 13.057  16.327  -12.292  1.00 30.87  ? 126  ARG B CA  1 
ATOM   4473  C C   . ARG B 1 133 ? 13.850  17.524  -12.826  1.00 30.13  ? 126  ARG B C   1 
ATOM   4474  O O   . ARG B 1 133 ? 14.728  17.321  -13.692  1.00 31.46  ? 126  ARG B O   1 
ATOM   4475  C CB  . ARG B 1 133 ? 11.575  16.460  -12.649  1.00 30.84  ? 126  ARG B CB  1 
ATOM   4476  C CG  . ARG B 1 133 ? 11.291  16.550  -14.147  1.00 32.83  ? 126  ARG B CG  1 
ATOM   4477  C CD  . ARG B 1 133 ? 9.807   16.739  -14.473  1.00 33.24  ? 126  ARG B CD  1 
ATOM   4478  N NE  . ARG B 1 133 ? 9.022   15.759  -13.739  1.00 34.68  ? 126  ARG B NE  1 
ATOM   4479  C CZ  . ARG B 1 133 ? 8.745   14.528  -14.152  1.00 33.81  ? 126  ARG B CZ  1 
ATOM   4480  N NH1 . ARG B 1 133 ? 9.120   14.104  -15.345  1.00 31.96  ? 126  ARG B NH1 1 
ATOM   4481  N NH2 . ARG B 1 133 ? 8.063   13.722  -13.363  1.00 36.24  ? 126  ARG B NH2 1 
ATOM   4482  N N   . ALA B 1 134 ? 13.556  18.712  -12.286  1.00 27.55  ? 127  ALA B N   1 
ATOM   4483  C CA  . ALA B 1 134 ? 14.217  19.991  -12.628  1.00 27.14  ? 127  ALA B CA  1 
ATOM   4484  C C   . ALA B 1 134 ? 15.743  19.876  -12.466  1.00 26.62  ? 127  ALA B C   1 
ATOM   4485  O O   . ALA B 1 134 ? 16.481  20.327  -13.363  1.00 25.13  ? 127  ALA B O   1 
ATOM   4486  C CB  . ALA B 1 134 ? 13.643  21.074  -11.763  1.00 26.45  ? 127  ALA B CB  1 
ATOM   4487  N N   . MET B 1 135 ? 16.199  19.287  -11.360  1.00 28.28  ? 128  MET B N   1 
ATOM   4488  C CA  . MET B 1 135 ? 17.648  19.155  -11.036  1.00 30.65  ? 128  MET B CA  1 
ATOM   4489  C C   . MET B 1 135 ? 18.314  18.188  -12.025  1.00 30.23  ? 128  MET B C   1 
ATOM   4490  O O   . MET B 1 135 ? 19.416  18.522  -12.531  1.00 27.91  ? 128  MET B O   1 
ATOM   4491  C CB  . MET B 1 135 ? 17.866  18.654  -9.605   1.00 34.83  ? 128  MET B CB  1 
ATOM   4492  C CG  . MET B 1 135 ? 17.419  19.641  -8.510   1.00 37.69  ? 128  MET B CG  1 
ATOM   4493  S SD  . MET B 1 135 ? 18.256  21.261  -8.520   1.00 42.29  ? 128  MET B SD  1 
ATOM   4494  C CE  . MET B 1 135 ? 18.012  21.776  -6.826   1.00 46.39  ? 128  MET B CE  1 
ATOM   4495  N N   . LEU B 1 136 ? 17.687  17.045  -12.324  1.00 28.19  ? 129  LEU B N   1 
ATOM   4496  C CA  . LEU B 1 136 ? 18.317  16.047  -13.224  1.00 26.59  ? 129  LEU B CA  1 
ATOM   4497  C C   . LEU B 1 136 ? 18.339  16.607  -14.647  1.00 25.94  ? 129  LEU B C   1 
ATOM   4498  O O   . LEU B 1 136 ? 19.320  16.350  -15.370  1.00 23.95  ? 129  LEU B O   1 
ATOM   4499  C CB  . LEU B 1 136 ? 17.557  14.724  -13.161  1.00 25.11  ? 129  LEU B CB  1 
ATOM   4500  C CG  . LEU B 1 136 ? 18.025  13.678  -14.177  1.00 24.20  ? 129  LEU B CG  1 
ATOM   4501  C CD1 . LEU B 1 136 ? 19.488  13.291  -13.958  1.00 22.79  ? 129  LEU B CD1 1 
ATOM   4502  C CD2 . LEU B 1 136 ? 17.131  12.447  -14.128  1.00 23.39  ? 129  LEU B CD2 1 
ATOM   4503  N N   . ALA B 1 137 ? 17.300  17.348  -15.027  1.00 26.12  ? 130  ALA B N   1 
ATOM   4504  C CA  . ALA B 1 137 ? 17.198  17.969  -16.363  1.00 28.97  ? 130  ALA B CA  1 
ATOM   4505  C C   . ALA B 1 137 ? 18.319  19.004  -16.515  1.00 31.55  ? 130  ALA B C   1 
ATOM   4506  O O   . ALA B 1 137 ? 18.964  19.024  -17.572  1.00 32.00  ? 130  ALA B O   1 
ATOM   4507  C CB  . ALA B 1 137 ? 15.834  18.579  -16.578  1.00 29.55  ? 130  ALA B CB  1 
ATOM   4508  N N   . LYS B 1 138 ? 18.528  19.833  -15.493  1.00 32.87  ? 131  LYS B N   1 
ATOM   4509  C CA  . LYS B 1 138 ? 19.597  20.859  -15.489  1.00 33.23  ? 131  LYS B CA  1 
ATOM   4510  C C   . LYS B 1 138 ? 20.943  20.148  -15.625  1.00 31.93  ? 131  LYS B C   1 
ATOM   4511  O O   . LYS B 1 138 ? 21.784  20.559  -16.460  1.00 32.42  ? 131  LYS B O   1 
ATOM   4512  C CB  . LYS B 1 138 ? 19.534  21.669  -14.191  1.00 35.59  ? 131  LYS B CB  1 
ATOM   4513  C CG  . LYS B 1 138 ? 20.686  22.644  -13.982  1.00 37.83  ? 131  LYS B CG  1 
ATOM   4514  C CD  . LYS B 1 138 ? 20.783  23.721  -15.069  1.00 40.20  ? 131  LYS B CD  1 
ATOM   4515  C CE  . LYS B 1 138 ? 22.134  24.402  -15.169  1.00 42.02  ? 131  LYS B CE  1 
ATOM   4516  N NZ  . LYS B 1 138 ? 22.499  24.656  -16.591  1.00 45.30  ? 131  LYS B NZ  1 
ATOM   4517  N N   . THR B 1 139 ? 21.130  19.115  -14.810  1.00 30.95  ? 132  THR B N   1 
ATOM   4518  C CA  . THR B 1 139 ? 22.354  18.279  -14.781  1.00 28.66  ? 132  THR B CA  1 
ATOM   4519  C C   . THR B 1 139 ? 22.586  17.694  -16.178  1.00 27.58  ? 132  THR B C   1 
ATOM   4520  O O   . THR B 1 139 ? 23.685  17.882  -16.721  1.00 26.96  ? 132  THR B O   1 
ATOM   4521  C CB  . THR B 1 139 ? 22.259  17.217  -13.678  1.00 28.60  ? 132  THR B CB  1 
ATOM   4522  O OG1 . THR B 1 139 ? 22.039  17.905  -12.446  1.00 27.90  ? 132  THR B OG1 1 
ATOM   4523  C CG2 . THR B 1 139 ? 23.494  16.348  -13.551  1.00 29.41  ? 132  THR B CG2 1 
ATOM   4524  N N   . LEU B 1 140 ? 21.585  17.030  -16.753  1.00 26.78  ? 133  LEU B N   1 
ATOM   4525  C CA  . LEU B 1 140 ? 21.751  16.368  -18.074  1.00 26.16  ? 133  LEU B CA  1 
ATOM   4526  C C   . LEU B 1 140 ? 22.038  17.413  -19.161  1.00 26.02  ? 133  LEU B C   1 
ATOM   4527  O O   . LEU B 1 140 ? 22.822  17.099  -20.065  1.00 24.62  ? 133  LEU B O   1 
ATOM   4528  C CB  . LEU B 1 140 ? 20.521  15.521  -18.393  1.00 25.16  ? 133  LEU B CB  1 
ATOM   4529  C CG  . LEU B 1 140 ? 20.509  14.137  -17.749  1.00 24.56  ? 133  LEU B CG  1 
ATOM   4530  C CD1 . LEU B 1 140 ? 19.213  13.407  -18.076  1.00 24.47  ? 133  LEU B CD1 1 
ATOM   4531  C CD2 . LEU B 1 140 ? 21.709  13.322  -18.198  1.00 23.85  ? 133  LEU B CD2 1 
ATOM   4532  N N   . ALA B 1 141 ? 21.487  18.624  -19.060  1.00 27.29  ? 134  ALA B N   1 
ATOM   4533  C CA  . ALA B 1 141 ? 21.769  19.728  -20.011  1.00 28.32  ? 134  ALA B CA  1 
ATOM   4534  C C   . ALA B 1 141 ? 23.260  20.103  -19.960  1.00 29.93  ? 134  ALA B C   1 
ATOM   4535  O O   . ALA B 1 141 ? 23.887  20.214  -21.015  1.00 31.53  ? 134  ALA B O   1 
ATOM   4536  C CB  . ALA B 1 141 ? 20.879  20.912  -19.714  1.00 28.38  ? 134  ALA B CB  1 
ATOM   4537  N N   . ALA B 1 142 ? 23.811  20.274  -18.758  1.00 32.51  ? 135  ALA B N   1 
ATOM   4538  C CA  . ALA B 1 142 ? 25.240  20.587  -18.533  1.00 32.75  ? 135  ALA B CA  1 
ATOM   4539  C C   . ALA B 1 142 ? 26.128  19.424  -18.998  1.00 32.80  ? 135  ALA B C   1 
ATOM   4540  O O   . ALA B 1 142 ? 27.226  19.697  -19.556  1.00 33.28  ? 135  ALA B O   1 
ATOM   4541  C CB  . ALA B 1 142 ? 25.469  20.902  -17.077  1.00 32.97  ? 135  ALA B CB  1 
ATOM   4542  N N   . LEU B 1 143 ? 25.686  18.183  -18.783  1.00 30.38  ? 136  LEU B N   1 
ATOM   4543  C CA  . LEU B 1 143 ? 26.490  16.972  -19.086  1.00 29.67  ? 136  LEU B CA  1 
ATOM   4544  C C   . LEU B 1 143 ? 26.520  16.725  -20.596  1.00 30.60  ? 136  LEU B C   1 
ATOM   4545  O O   . LEU B 1 143 ? 27.509  16.140  -21.069  1.00 28.42  ? 136  LEU B O   1 
ATOM   4546  C CB  . LEU B 1 143 ? 25.875  15.768  -18.375  1.00 28.96  ? 136  LEU B CB  1 
ATOM   4547  C CG  . LEU B 1 143 ? 26.659  14.460  -18.505  1.00 28.15  ? 136  LEU B CG  1 
ATOM   4548  C CD1 . LEU B 1 143 ? 28.040  14.618  -17.884  1.00 27.19  ? 136  LEU B CD1 1 
ATOM   4549  C CD2 . LEU B 1 143 ? 25.892  13.307  -17.861  1.00 27.30  ? 136  LEU B CD2 1 
ATOM   4550  N N   . THR B 1 144 ? 25.469  17.121  -21.321  1.00 31.53  ? 137  THR B N   1 
ATOM   4551  C CA  . THR B 1 144 ? 25.321  16.804  -22.756  1.00 32.06  ? 137  THR B CA  1 
ATOM   4552  C C   . THR B 1 144 ? 25.985  17.864  -23.621  1.00 36.88  ? 137  THR B C   1 
ATOM   4553  O O   . THR B 1 144 ? 26.079  19.035  -23.248  1.00 34.56  ? 137  THR B O   1 
ATOM   4554  C CB  . THR B 1 144 ? 23.863  16.680  -23.205  1.00 31.23  ? 137  THR B CB  1 
ATOM   4555  O OG1 . THR B 1 144 ? 23.170  17.857  -22.794  1.00 28.44  ? 137  THR B OG1 1 
ATOM   4556  C CG2 . THR B 1 144 ? 23.221  15.412  -22.691  1.00 30.38  ? 137  THR B CG2 1 
ATOM   4557  N N   . PRO B 1 145 ? 26.407  17.452  -24.838  1.00 41.00  ? 138  PRO B N   1 
ATOM   4558  C CA  . PRO B 1 145 ? 27.050  18.355  -25.782  1.00 47.04  ? 138  PRO B CA  1 
ATOM   4559  C C   . PRO B 1 145 ? 26.105  19.409  -26.375  1.00 48.57  ? 138  PRO B C   1 
ATOM   4560  O O   . PRO B 1 145 ? 24.944  19.123  -26.570  1.00 50.39  ? 138  PRO B O   1 
ATOM   4561  C CB  . PRO B 1 145 ? 27.577  17.427  -26.892  1.00 46.68  ? 138  PRO B CB  1 
ATOM   4562  C CG  . PRO B 1 145 ? 26.732  16.171  -26.794  1.00 42.95  ? 138  PRO B CG  1 
ATOM   4563  C CD  . PRO B 1 145 ? 26.337  16.068  -25.342  1.00 40.95  ? 138  PRO B CD  1 
ATOM   4564  N N   . GLY B 1 146 ? 26.662  20.601  -26.601  1.00 50.99  ? 139  GLY B N   1 
ATOM   4565  C CA  . GLY B 1 146 ? 26.115  21.686  -27.428  1.00 49.30  ? 139  GLY B CA  1 
ATOM   4566  C C   . GLY B 1 146 ? 24.724  22.106  -26.999  1.00 50.67  ? 139  GLY B C   1 
ATOM   4567  O O   . GLY B 1 146 ? 24.538  22.455  -25.810  1.00 50.20  ? 139  GLY B O   1 
ATOM   4568  N N   . LYS B 1 147 ? 23.786  22.025  -27.939  1.00 49.25  ? 140  LYS B N   1 
ATOM   4569  C CA  . LYS B 1 147 ? 22.468  22.685  -27.870  1.00 49.41  ? 140  LYS B CA  1 
ATOM   4570  C C   . LYS B 1 147 ? 21.432  21.693  -27.316  1.00 45.18  ? 140  LYS B C   1 
ATOM   4571  O O   . LYS B 1 147 ? 20.249  22.080  -27.237  1.00 42.43  ? 140  LYS B O   1 
ATOM   4572  C CB  . LYS B 1 147 ? 22.086  23.218  -29.259  1.00 55.07  ? 140  LYS B CB  1 
ATOM   4573  C CG  . LYS B 1 147 ? 23.167  23.932  -30.068  1.00 63.12  ? 140  LYS B CG  1 
ATOM   4574  C CD  . LYS B 1 147 ? 22.969  25.429  -30.214  1.00 71.47  ? 140  LYS B CD  1 
ATOM   4575  C CE  . LYS B 1 147 ? 23.447  26.199  -28.997  1.00 84.53  ? 140  LYS B CE  1 
ATOM   4576  N NZ  . LYS B 1 147 ? 22.808  27.532  -28.901  1.00 89.44  ? 140  LYS B NZ  1 
ATOM   4577  N N   . LEU B 1 148 ? 21.838  20.470  -26.939  1.00 38.26  ? 141  LEU B N   1 
ATOM   4578  C CA  . LEU B 1 148 ? 20.976  19.538  -26.161  1.00 35.29  ? 141  LEU B CA  1 
ATOM   4579  C C   . LEU B 1 148 ? 20.658  20.181  -24.804  1.00 33.53  ? 141  LEU B C   1 
ATOM   4580  O O   . LEU B 1 148 ? 21.596  20.423  -24.020  1.00 29.61  ? 141  LEU B O   1 
ATOM   4581  C CB  . LEU B 1 148 ? 21.670  18.188  -25.993  1.00 35.79  ? 141  LEU B CB  1 
ATOM   4582  C CG  . LEU B 1 148 ? 21.722  17.337  -27.252  1.00 38.53  ? 141  LEU B CG  1 
ATOM   4583  C CD1 . LEU B 1 148 ? 22.478  16.050  -26.988  1.00 40.52  ? 141  LEU B CD1 1 
ATOM   4584  C CD2 . LEU B 1 148 ? 20.326  17.032  -27.782  1.00 40.93  ? 141  LEU B CD2 1 
ATOM   4585  N N   . LYS B 1 149 ? 19.373  20.449  -24.548  1.00 34.45  ? 142  LYS B N   1 
ATOM   4586  C CA  . LYS B 1 149 ? 18.922  21.383  -23.485  1.00 32.83  ? 142  LYS B CA  1 
ATOM   4587  C C   . LYS B 1 149 ? 17.696  20.845  -22.738  1.00 32.14  ? 142  LYS B C   1 
ATOM   4588  O O   . LYS B 1 149 ? 17.607  21.109  -21.534  1.00 35.83  ? 142  LYS B O   1 
ATOM   4589  C CB  . LYS B 1 149 ? 18.627  22.750  -24.106  1.00 33.76  ? 142  LYS B CB  1 
ATOM   4590  C CG  . LYS B 1 149 ? 18.288  23.856  -23.117  1.00 36.50  ? 142  LYS B CG  1 
ATOM   4591  C CD  . LYS B 1 149 ? 18.371  25.250  -23.709  1.00 38.34  ? 142  LYS B CD  1 
ATOM   4592  C CE  . LYS B 1 149 ? 18.085  26.344  -22.697  1.00 39.77  ? 142  LYS B CE  1 
ATOM   4593  N NZ  . LYS B 1 149 ? 16.634  26.600  -22.584  1.00 38.64  ? 142  LYS B NZ  1 
ATOM   4594  N N   . TYR B 1 150 ? 16.749  20.183  -23.403  1.00 29.70  ? 143  TYR B N   1 
ATOM   4595  C CA  . TYR B 1 150 ? 15.480  19.766  -22.759  1.00 28.00  ? 143  TYR B CA  1 
ATOM   4596  C C   . TYR B 1 150 ? 15.490  18.255  -22.619  1.00 25.91  ? 143  TYR B C   1 
ATOM   4597  O O   . TYR B 1 150 ? 16.000  17.574  -23.500  1.00 25.82  ? 143  TYR B O   1 
ATOM   4598  C CB  . TYR B 1 150 ? 14.263  20.310  -23.499  1.00 29.01  ? 143  TYR B CB  1 
ATOM   4599  C CG  . TYR B 1 150 ? 13.994  21.762  -23.201  1.00 32.36  ? 143  TYR B CG  1 
ATOM   4600  C CD1 . TYR B 1 150 ? 14.613  22.763  -23.924  1.00 35.83  ? 143  TYR B CD1 1 
ATOM   4601  C CD2 . TYR B 1 150 ? 13.149  22.147  -22.177  1.00 33.81  ? 143  TYR B CD2 1 
ATOM   4602  C CE1 . TYR B 1 150 ? 14.388  24.108  -23.660  1.00 37.84  ? 143  TYR B CE1 1 
ATOM   4603  C CE2 . TYR B 1 150 ? 12.925  23.483  -21.882  1.00 35.43  ? 143  TYR B CE2 1 
ATOM   4604  C CZ  . TYR B 1 150 ? 13.549  24.471  -22.624  1.00 36.09  ? 143  TYR B CZ  1 
ATOM   4605  O OH  . TYR B 1 150 ? 13.362  25.799  -22.359  1.00 37.97  ? 143  TYR B OH  1 
ATOM   4606  N N   . SER B 1 151 ? 14.986  17.785  -21.480  1.00 25.31  ? 144  SER B N   1 
ATOM   4607  C CA  . SER B 1 151 ? 14.916  16.358  -21.088  1.00 23.32  ? 144  SER B CA  1 
ATOM   4608  C C   . SER B 1 151 ? 13.462  15.975  -20.800  1.00 22.82  ? 144  SER B C   1 
ATOM   4609  O O   . SER B 1 151 ? 12.731  16.768  -20.188  1.00 21.73  ? 144  SER B O   1 
ATOM   4610  C CB  . SER B 1 151 ? 15.808  16.075  -19.930  1.00 23.08  ? 144  SER B CB  1 
ATOM   4611  O OG  . SER B 1 151 ? 17.140  16.467  -20.223  1.00 23.17  ? 144  SER B OG  1 
ATOM   4612  N N   . PHE B 1 152 ? 13.065  14.822  -21.323  1.00 23.86  ? 145  PHE B N   1 
ATOM   4613  C CA  . PHE B 1 152 ? 11.817  14.101  -21.019  1.00 24.50  ? 145  PHE B CA  1 
ATOM   4614  C C   . PHE B 1 152 ? 12.200  12.751  -20.420  1.00 24.92  ? 145  PHE B C   1 
ATOM   4615  O O   . PHE B 1 152 ? 12.970  12.015  -21.065  1.00 23.35  ? 145  PHE B O   1 
ATOM   4616  C CB  . PHE B 1 152 ? 10.992  13.886  -22.285  1.00 27.01  ? 145  PHE B CB  1 
ATOM   4617  C CG  . PHE B 1 152 ? 9.826   12.963  -22.044  1.00 26.98  ? 145  PHE B CG  1 
ATOM   4618  C CD1 . PHE B 1 152 ? 8.643   13.455  -21.527  1.00 27.60  ? 145  PHE B CD1 1 
ATOM   4619  C CD2 . PHE B 1 152 ? 9.955   11.597  -22.243  1.00 27.02  ? 145  PHE B CD2 1 
ATOM   4620  C CE1 . PHE B 1 152 ? 7.594   12.597  -21.248  1.00 29.72  ? 145  PHE B CE1 1 
ATOM   4621  C CE2 . PHE B 1 152 ? 8.902   10.742  -21.984  1.00 26.60  ? 145  PHE B CE2 1 
ATOM   4622  C CZ  . PHE B 1 152 ? 7.729   11.244  -21.476  1.00 29.33  ? 145  PHE B CZ  1 
ATOM   4623  N N   . PHE B 1 153 ? 11.668  12.433  -19.235  1.00 25.79  ? 146  PHE B N   1 
ATOM   4624  C CA  . PHE B 1 153 ? 12.023  11.218  -18.457  1.00 24.37  ? 146  PHE B CA  1 
ATOM   4625  C C   . PHE B 1 153 ? 10.925  10.173  -18.574  1.00 23.05  ? 146  PHE B C   1 
ATOM   4626  O O   . PHE B 1 153 ? 9.745   10.513  -18.504  1.00 23.27  ? 146  PHE B O   1 
ATOM   4627  C CB  . PHE B 1 153 ? 12.280  11.592  -17.007  1.00 24.40  ? 146  PHE B CB  1 
ATOM   4628  C CG  . PHE B 1 153 ? 13.381  12.603  -16.883  1.00 26.33  ? 146  PHE B CG  1 
ATOM   4629  C CD1 . PHE B 1 153 ? 14.680  12.255  -17.231  1.00 26.87  ? 146  PHE B CD1 1 
ATOM   4630  C CD2 . PHE B 1 153 ? 13.119  13.897  -16.458  1.00 27.30  ? 146  PHE B CD2 1 
ATOM   4631  C CE1 . PHE B 1 153 ? 15.699  13.182  -17.141  1.00 26.60  ? 146  PHE B CE1 1 
ATOM   4632  C CE2 . PHE B 1 153 ? 14.153  14.816  -16.349  1.00 29.59  ? 146  PHE B CE2 1 
ATOM   4633  C CZ  . PHE B 1 153 ? 15.436  14.460  -16.701  1.00 27.51  ? 146  PHE B CZ  1 
ATOM   4634  N N   . CYS B 1 154 ? 11.353  8.936   -18.781  1.00 22.21  ? 147  CYS B N   1 
ATOM   4635  C CA  . CYS B 1 154 ? 10.490  7.749   -18.935  1.00 22.25  ? 147  CYS B CA  1 
ATOM   4636  C C   . CYS B 1 154 ? 11.136  6.632   -18.122  1.00 21.13  ? 147  CYS B C   1 
ATOM   4637  O O   . CYS B 1 154 ? 11.986  6.958   -17.270  1.00 20.19  ? 147  CYS B O   1 
ATOM   4638  C CB  . CYS B 1 154 ? 10.309  7.414   -20.409  1.00 23.06  ? 147  CYS B CB  1 
ATOM   4639  S SG  . CYS B 1 154 ? 11.847  7.456   -21.369  1.00 24.48  ? 147  CYS B SG  1 
ATOM   4640  N N   . ASN B 1 155 ? 10.763  5.382   -18.376  1.00 20.74  ? 148  ASN B N   1 
ATOM   4641  C CA  . ASN B 1 155 ? 11.094  4.245   -17.488  1.00 20.93  ? 148  ASN B CA  1 
ATOM   4642  C C   . ASN B 1 155 ? 11.940  3.192   -18.206  1.00 22.07  ? 148  ASN B C   1 
ATOM   4643  O O   . ASN B 1 155 ? 12.310  2.226   -17.526  1.00 22.72  ? 148  ASN B O   1 
ATOM   4644  C CB  . ASN B 1 155 ? 9.828   3.614   -16.922  1.00 21.01  ? 148  ASN B CB  1 
ATOM   4645  C CG  . ASN B 1 155 ? 8.910   4.630   -16.271  1.00 21.92  ? 148  ASN B CG  1 
ATOM   4646  O OD1 . ASN B 1 155 ? 9.244   5.212   -15.239  1.00 21.32  ? 148  ASN B OD1 1 
ATOM   4647  N ND2 . ASN B 1 155 ? 7.751   4.850   -16.870  1.00 23.66  ? 148  ASN B ND2 1 
ATOM   4648  N N   . SER B 1 156 ? 12.254  3.343   -19.498  1.00 21.15  ? 149  SER B N   1 
ATOM   4649  C CA  . SER B 1 156 ? 13.022  2.303   -20.239  1.00 20.98  ? 149  SER B CA  1 
ATOM   4650  C C   . SER B 1 156 ? 13.677  2.861   -21.508  1.00 20.43  ? 149  SER B C   1 
ATOM   4651  O O   . SER B 1 156 ? 13.314  3.981   -21.939  1.00 20.12  ? 149  SER B O   1 
ATOM   4652  C CB  . SER B 1 156 ? 12.128  1.140   -20.555  1.00 20.79  ? 149  SER B CB  1 
ATOM   4653  O OG  . SER B 1 156 ? 11.086  1.550   -21.406  1.00 20.19  ? 149  SER B OG  1 
ATOM   4654  N N   . GLY B 1 157 ? 14.608  2.101   -22.091  1.00 19.27  ? 150  GLY B N   1 
ATOM   4655  C CA  . GLY B 1 157 ? 15.196  2.440   -23.396  1.00 18.40  ? 150  GLY B CA  1 
ATOM   4656  C C   . GLY B 1 157 ? 14.099  2.567   -24.449  1.00 18.63  ? 150  GLY B C   1 
ATOM   4657  O O   . GLY B 1 157 ? 14.044  3.595   -25.161  1.00 18.56  ? 150  GLY B O   1 
ATOM   4658  N N   . THR B 1 158 ? 13.224  1.576   -24.544  1.00 18.17  ? 151  THR B N   1 
ATOM   4659  C CA  . THR B 1 158 ? 12.170  1.546   -25.590  1.00 19.27  ? 151  THR B CA  1 
ATOM   4660  C C   . THR B 1 158 ? 11.269  2.784   -25.439  1.00 18.32  ? 151  THR B C   1 
ATOM   4661  O O   . THR B 1 158 ? 10.942  3.379   -26.467  1.00 18.30  ? 151  THR B O   1 
ATOM   4662  C CB  . THR B 1 158 ? 11.453  0.196   -25.580  1.00 18.49  ? 151  THR B CB  1 
ATOM   4663  O OG1 . THR B 1 158 ? 10.759  0.104   -26.814  1.00 18.04  ? 151  THR B OG1 1 
ATOM   4664  C CG2 . THR B 1 158 ? 10.505  0.028   -24.426  1.00 18.64  ? 151  THR B CG2 1 
ATOM   4665  N N   . GLU B 1 159 ? 10.966  3.213   -24.218  1.00 18.83  ? 152  GLU B N   1 
ATOM   4666  C CA  . GLU B 1 159 ? 10.138  4.428   -23.988  1.00 20.36  ? 152  GLU B CA  1 
ATOM   4667  C C   . GLU B 1 159 ? 10.926  5.666   -24.443  1.00 19.82  ? 152  GLU B C   1 
ATOM   4668  O O   . GLU B 1 159 ? 10.320  6.570   -25.008  1.00 20.33  ? 152  GLU B O   1 
ATOM   4669  C CB  . GLU B 1 159 ? 9.695   4.589   -22.529  1.00 22.23  ? 152  GLU B CB  1 
ATOM   4670  C CG  . GLU B 1 159 ? 8.443   3.816   -22.134  1.00 24.02  ? 152  GLU B CG  1 
ATOM   4671  C CD  . GLU B 1 159 ? 7.889   4.076   -20.725  1.00 24.57  ? 152  GLU B CD  1 
ATOM   4672  O OE1 . GLU B 1 159 ? 8.666   4.221   -19.801  1.00 22.85  ? 152  GLU B OE1 1 
ATOM   4673  O OE2 . GLU B 1 159 ? 6.650   4.161   -20.560  1.00 28.93  ? 152  GLU B OE2 1 
ATOM   4674  N N   A SER B 1 160 ? 12.233  5.712   -24.188  0.50 20.03  ? 153  SER B N   1 
ATOM   4675  N N   B SER B 1 160 ? 12.234  5.709   -24.192  0.50 20.21  ? 153  SER B N   1 
ATOM   4676  C CA  A SER B 1 160 ? 13.100  6.862   -24.562  0.50 20.40  ? 153  SER B CA  1 
ATOM   4677  C CA  B SER B 1 160 ? 13.102  6.858   -24.564  0.50 20.70  ? 153  SER B CA  1 
ATOM   4678  C C   A SER B 1 160 ? 13.144  6.987   -26.081  0.50 20.94  ? 153  SER B C   1 
ATOM   4679  C C   B SER B 1 160 ? 13.144  6.986   -26.082  0.50 21.11  ? 153  SER B C   1 
ATOM   4680  O O   A SER B 1 160 ? 13.144  8.130   -26.577  0.50 22.18  ? 153  SER B O   1 
ATOM   4681  O O   B SER B 1 160 ? 13.142  8.129   -26.578  0.50 22.35  ? 153  SER B O   1 
ATOM   4682  C CB  A SER B 1 160 ? 14.503  6.756   -23.980  0.50 21.04  ? 153  SER B CB  1 
ATOM   4683  C CB  B SER B 1 160 ? 14.502  6.766   -23.963  0.50 21.58  ? 153  SER B CB  1 
ATOM   4684  O OG  A SER B 1 160 ? 15.334  7.780   -24.510  0.50 20.24  ? 153  SER B OG  1 
ATOM   4685  O OG  B SER B 1 160 ? 15.268  5.688   -24.474  0.50 21.23  ? 153  SER B OG  1 
ATOM   4686  N N   . VAL B 1 161 ? 13.142  5.853   -26.787  1.00 21.03  ? 154  VAL B N   1 
ATOM   4687  C CA  . VAL B 1 161 ? 13.139  5.819   -28.276  1.00 21.93  ? 154  VAL B CA  1 
ATOM   4688  C C   . VAL B 1 161 ? 11.759  6.279   -28.765  1.00 22.68  ? 154  VAL B C   1 
ATOM   4689  O O   . VAL B 1 161 ? 11.701  7.110   -29.705  1.00 22.74  ? 154  VAL B O   1 
ATOM   4690  C CB  . VAL B 1 161 ? 13.562  4.426   -28.795  1.00 22.57  ? 154  VAL B CB  1 
ATOM   4691  C CG1 . VAL B 1 161 ? 13.184  4.208   -30.244  1.00 22.86  ? 154  VAL B CG1 1 
ATOM   4692  C CG2 . VAL B 1 161 ? 15.054  4.201   -28.619  1.00 21.68  ? 154  VAL B CG2 1 
ATOM   4693  N N   . GLU B 1 162 ? 10.679  5.806   -28.139  1.00 23.43  ? 155  GLU B N   1 
ATOM   4694  C CA  . GLU B 1 162 ? 9.300   6.229   -28.508  1.00 22.43  ? 155  GLU B CA  1 
ATOM   4695  C C   . GLU B 1 162 ? 9.214   7.748   -28.428  1.00 20.83  ? 155  GLU B C   1 
ATOM   4696  O O   . GLU B 1 162 ? 8.733   8.363   -29.373  1.00 21.41  ? 155  GLU B O   1 
ATOM   4697  C CB  . GLU B 1 162 ? 8.252   5.616   -27.593  1.00 24.32  ? 155  GLU B CB  1 
ATOM   4698  C CG  . GLU B 1 162 ? 8.145   4.110   -27.724  1.00 26.44  ? 155  GLU B CG  1 
ATOM   4699  C CD  . GLU B 1 162 ? 7.345   3.598   -28.907  1.00 26.89  ? 155  GLU B CD  1 
ATOM   4700  O OE1 . GLU B 1 162 ? 6.592   4.411   -29.509  1.00 31.49  ? 155  GLU B OE1 1 
ATOM   4701  O OE2 . GLU B 1 162 ? 7.478   2.392   -29.214  1.00 26.30  ? 155  GLU B OE2 1 
ATOM   4702  N N   . ALA B 1 163 ? 9.725   8.322   -27.345  1.00 19.37  ? 156  ALA B N   1 
ATOM   4703  C CA  . ALA B 1 163 ? 9.730   9.783   -27.110  1.00 19.47  ? 156  ALA B CA  1 
ATOM   4704  C C   . ALA B 1 163 ? 10.491  10.491  -28.233  1.00 19.58  ? 156  ALA B C   1 
ATOM   4705  O O   . ALA B 1 163 ? 10.017  11.536  -28.716  1.00 18.43  ? 156  ALA B O   1 
ATOM   4706  C CB  . ALA B 1 163 ? 10.298  10.084  -25.748  1.00 19.52  ? 156  ALA B CB  1 
ATOM   4707  N N   . ALA B 1 164 ? 11.625  9.927   -28.643  1.00 20.38  ? 157  ALA B N   1 
ATOM   4708  C CA  . ALA B 1 164 ? 12.474  10.498  -29.708  1.00 21.42  ? 157  ALA B CA  1 
ATOM   4709  C C   . ALA B 1 164 ? 11.692  10.505  -31.029  1.00 21.14  ? 157  ALA B C   1 
ATOM   4710  O O   . ALA B 1 164 ? 11.540  11.577  -31.664  1.00 20.20  ? 157  ALA B O   1 
ATOM   4711  C CB  . ALA B 1 164 ? 13.756  9.705   -29.809  1.00 21.92  ? 157  ALA B CB  1 
ATOM   4712  N N   . LEU B 1 165 ? 11.203  9.334   -31.417  1.00 22.00  ? 158  LEU B N   1 
ATOM   4713  C CA  . LEU B 1 165 ? 10.372  9.158   -32.636  1.00 21.62  ? 158  LEU B CA  1 
ATOM   4714  C C   . LEU B 1 165 ? 9.249   10.189  -32.591  1.00 20.12  ? 158  LEU B C   1 
ATOM   4715  O O   . LEU B 1 165 ? 8.976   10.806  -33.625  1.00 21.09  ? 158  LEU B O   1 
ATOM   4716  C CB  . LEU B 1 165 ? 9.832   7.722   -32.700  1.00 22.17  ? 158  LEU B CB  1 
ATOM   4717  C CG  . LEU B 1 165 ? 10.902  6.634   -32.916  1.00 23.13  ? 158  LEU B CG  1 
ATOM   4718  C CD1 . LEU B 1 165 ? 10.310  5.233   -32.861  1.00 23.48  ? 158  LEU B CD1 1 
ATOM   4719  C CD2 . LEU B 1 165 ? 11.632  6.817   -34.231  1.00 22.53  ? 158  LEU B CD2 1 
ATOM   4720  N N   . LYS B 1 166 ? 8.651   10.393  -31.422  1.00 20.03  ? 159  LYS B N   1 
ATOM   4721  C CA  . LYS B 1 166 ? 7.481   11.299  -31.283  1.00 20.45  ? 159  LYS B CA  1 
ATOM   4722  C C   . LYS B 1 166 ? 7.936   12.752  -31.441  1.00 19.76  ? 159  LYS B C   1 
ATOM   4723  O O   . LYS B 1 166 ? 7.280   13.497  -32.191  1.00 18.67  ? 159  LYS B O   1 
ATOM   4724  C CB  . LYS B 1 166 ? 6.724   11.014  -29.985  1.00 20.89  ? 159  LYS B CB  1 
ATOM   4725  C CG  . LYS B 1 166 ? 5.824   9.784   -30.042  1.00 20.88  ? 159  LYS B CG  1 
ATOM   4726  C CD  . LYS B 1 166 ? 4.939   9.588   -28.817  1.00 21.53  ? 159  LYS B CD  1 
ATOM   4727  C CE  . LYS B 1 166 ? 3.799   10.586  -28.715  1.00 21.80  ? 159  LYS B CE  1 
ATOM   4728  N NZ  . LYS B 1 166 ? 2.978   10.400  -27.484  1.00 21.76  ? 159  LYS B NZ  1 
ATOM   4729  N N   . LEU B 1 167 ? 9.049   13.137  -30.823  1.00 20.38  ? 160  LEU B N   1 
ATOM   4730  C CA  . LEU B 1 167 ? 9.600   14.508  -31.005  1.00 20.63  ? 160  LEU B CA  1 
ATOM   4731  C C   . LEU B 1 167 ? 9.825   14.746  -32.498  1.00 20.69  ? 160  LEU B C   1 
ATOM   4732  O O   . LEU B 1 167 ? 9.370   15.778  -33.014  1.00 21.76  ? 160  LEU B O   1 
ATOM   4733  C CB  . LEU B 1 167 ? 10.892  14.657  -30.202  1.00 21.34  ? 160  LEU B CB  1 
ATOM   4734  C CG  . LEU B 1 167 ? 10.698  14.783  -28.690  1.00 21.30  ? 160  LEU B CG  1 
ATOM   4735  C CD1 . LEU B 1 167 ? 12.020  14.715  -27.981  1.00 21.96  ? 160  LEU B CD1 1 
ATOM   4736  C CD2 . LEU B 1 167 ? 10.001  16.077  -28.326  1.00 22.01  ? 160  LEU B CD2 1 
ATOM   4737  N N   . ALA B 1 168 ? 10.423  13.782  -33.186  1.00 19.80  ? 161  ALA B N   1 
ATOM   4738  C CA  . ALA B 1 168 ? 10.740  13.900  -34.626  1.00 20.32  ? 161  ALA B CA  1 
ATOM   4739  C C   . ALA B 1 168 ? 9.444   14.063  -35.420  1.00 20.43  ? 161  ALA B C   1 
ATOM   4740  O O   . ALA B 1 168 ? 9.365   14.973  -36.289  1.00 21.53  ? 161  ALA B O   1 
ATOM   4741  C CB  . ALA B 1 168 ? 11.519  12.697  -35.083  1.00 20.70  ? 161  ALA B CB  1 
ATOM   4742  N N   . LYS B 1 169 ? 8.454   13.220  -35.127  1.00 19.28  ? 162  LYS B N   1 
ATOM   4743  C CA  . LYS B 1 169 ? 7.172   13.215  -35.859  1.00 18.26  ? 162  LYS B CA  1 
ATOM   4744  C C   . LYS B 1 169 ? 6.535   14.593  -35.709  1.00 18.65  ? 162  LYS B C   1 
ATOM   4745  O O   . LYS B 1 169 ? 6.086   15.143  -36.709  1.00 18.81  ? 162  LYS B O   1 
ATOM   4746  C CB  . LYS B 1 169 ? 6.283   12.080  -35.358  1.00 17.63  ? 162  LYS B CB  1 
ATOM   4747  C CG  . LYS B 1 169 ? 6.621   10.692  -35.889  1.00 17.11  ? 162  LYS B CG  1 
ATOM   4748  C CD  . LYS B 1 169 ? 5.641   9.653   -35.373  1.00 16.58  ? 162  LYS B CD  1 
ATOM   4749  C CE  . LYS B 1 169 ? 5.666   8.334   -36.108  1.00 16.64  ? 162  LYS B CE  1 
ATOM   4750  N NZ  . LYS B 1 169 ? 4.795   8.347   -37.303  1.00 16.80  ? 162  LYS B NZ  1 
ATOM   4751  N N   . ALA B 1 170 ? 6.519   15.142  -34.505  1.00 21.04  ? 163  ALA B N   1 
ATOM   4752  C CA  . ALA B 1 170 ? 5.828   16.416  -34.202  1.00 22.38  ? 163  ALA B CA  1 
ATOM   4753  C C   . ALA B 1 170 ? 6.589   17.562  -34.883  1.00 22.25  ? 163  ALA B C   1 
ATOM   4754  O O   . ALA B 1 170 ? 5.945   18.526  -35.347  1.00 20.90  ? 163  ALA B O   1 
ATOM   4755  C CB  . ALA B 1 170 ? 5.723   16.612  -32.700  1.00 23.97  ? 163  ALA B CB  1 
ATOM   4756  N N   . TYR B 1 171 ? 7.914   17.470  -34.936  1.00 21.78  ? 164  TYR B N   1 
ATOM   4757  C CA  . TYR B 1 171 ? 8.748   18.525  -35.547  1.00 23.73  ? 164  TYR B CA  1 
ATOM   4758  C C   . TYR B 1 171 ? 8.551   18.508  -37.062  1.00 25.49  ? 164  TYR B C   1 
ATOM   4759  O O   . TYR B 1 171 ? 8.416   19.590  -37.660  1.00 26.12  ? 164  TYR B O   1 
ATOM   4760  C CB  . TYR B 1 171 ? 10.228  18.330  -35.227  1.00 26.08  ? 164  TYR B CB  1 
ATOM   4761  C CG  . TYR B 1 171 ? 11.075  19.508  -35.626  1.00 28.49  ? 164  TYR B CG  1 
ATOM   4762  C CD1 . TYR B 1 171 ? 11.064  20.673  -34.877  1.00 30.03  ? 164  TYR B CD1 1 
ATOM   4763  C CD2 . TYR B 1 171 ? 11.854  19.488  -36.774  1.00 30.37  ? 164  TYR B CD2 1 
ATOM   4764  C CE1 . TYR B 1 171 ? 11.837  21.773  -35.229  1.00 32.11  ? 164  TYR B CE1 1 
ATOM   4765  C CE2 . TYR B 1 171 ? 12.626  20.582  -37.147  1.00 31.22  ? 164  TYR B CE2 1 
ATOM   4766  C CZ  . TYR B 1 171 ? 12.626  21.729  -36.364  1.00 31.84  ? 164  TYR B CZ  1 
ATOM   4767  O OH  . TYR B 1 171 ? 13.365  22.831  -36.685  1.00 31.69  ? 164  TYR B OH  1 
ATOM   4768  N N   . GLN B 1 172 ? 8.504   17.311  -37.652  1.00 25.03  ? 165  GLN B N   1 
ATOM   4769  C CA  . GLN B 1 172 ? 8.734   17.111  -39.103  1.00 26.72  ? 165  GLN B CA  1 
ATOM   4770  C C   . GLN B 1 172 ? 7.431   16.984  -39.905  1.00 27.41  ? 165  GLN B C   1 
ATOM   4771  O O   . GLN B 1 172 ? 7.483   17.335  -41.103  1.00 24.59  ? 165  GLN B O   1 
ATOM   4772  C CB  . GLN B 1 172 ? 9.649   15.904  -39.312  1.00 26.35  ? 165  GLN B CB  1 
ATOM   4773  C CG  . GLN B 1 172 ? 11.089  16.144  -38.884  1.00 24.75  ? 165  GLN B CG  1 
ATOM   4774  C CD  . GLN B 1 172 ? 11.863  17.073  -39.786  1.00 22.39  ? 165  GLN B CD  1 
ATOM   4775  O OE1 . GLN B 1 172 ? 11.490  18.215  -40.010  1.00 21.61  ? 165  GLN B OE1 1 
ATOM   4776  N NE2 . GLN B 1 172 ? 12.986  16.601  -40.279  1.00 21.31  ? 165  GLN B NE2 1 
ATOM   4777  N N   . SER B 1 173 ? 6.317   16.524  -39.315  1.00 29.45  ? 166  SER B N   1 
ATOM   4778  C CA  . SER B 1 173 ? 5.038   16.331  -40.053  1.00 30.50  ? 166  SER B CA  1 
ATOM   4779  C C   . SER B 1 173 ? 4.522   17.680  -40.561  1.00 30.48  ? 166  SER B C   1 
ATOM   4780  O O   . SER B 1 173 ? 4.171   17.789  -41.733  1.00 29.54  ? 166  SER B O   1 
ATOM   4781  C CB  . SER B 1 173 ? 4.032   15.558  -39.254  1.00 33.44  ? 166  SER B CB  1 
ATOM   4782  O OG  . SER B 1 173 ? 3.307   16.388  -38.368  1.00 41.98  ? 166  SER B OG  1 
ATOM   4783  N N   . PRO B 1 174 ? 4.579   18.778  -39.770  1.00 29.89  ? 167  PRO B N   1 
ATOM   4784  C CA  . PRO B 1 174 ? 4.210   20.097  -40.279  1.00 30.23  ? 167  PRO B CA  1 
ATOM   4785  C C   . PRO B 1 174 ? 5.198   20.595  -41.345  1.00 30.05  ? 167  PRO B C   1 
ATOM   4786  O O   . PRO B 1 174 ? 4.879   21.531  -42.032  1.00 30.66  ? 167  PRO B O   1 
ATOM   4787  C CB  . PRO B 1 174 ? 4.294   21.051  -39.072  1.00 30.20  ? 167  PRO B CB  1 
ATOM   4788  C CG  . PRO B 1 174 ? 4.643   20.194  -37.878  1.00 29.41  ? 167  PRO B CG  1 
ATOM   4789  C CD  . PRO B 1 174 ? 5.111   18.853  -38.405  1.00 29.14  ? 167  PRO B CD  1 
ATOM   4790  N N   . ARG B 1 175 ? 6.392   20.001  -41.406  1.00 29.60  ? 168  ARG B N   1 
ATOM   4791  C CA  . ARG B 1 175 ? 7.390   20.275  -42.465  1.00 31.54  ? 168  ARG B CA  1 
ATOM   4792  C C   . ARG B 1 175 ? 7.234   19.267  -43.616  1.00 31.40  ? 168  ARG B C   1 
ATOM   4793  O O   . ARG B 1 175 ? 8.035   19.337  -44.550  1.00 30.42  ? 168  ARG B O   1 
ATOM   4794  C CB  . ARG B 1 175 ? 8.784   20.276  -41.843  1.00 34.62  ? 168  ARG B CB  1 
ATOM   4795  C CG  . ARG B 1 175 ? 8.989   21.435  -40.884  1.00 37.27  ? 168  ARG B CG  1 
ATOM   4796  C CD  . ARG B 1 175 ? 10.291  21.338  -40.120  1.00 40.65  ? 168  ARG B CD  1 
ATOM   4797  N NE  . ARG B 1 175 ? 10.585  22.586  -39.433  1.00 43.25  ? 168  ARG B NE  1 
ATOM   4798  C CZ  . ARG B 1 175 ? 10.045  22.960  -38.276  1.00 47.46  ? 168  ARG B CZ  1 
ATOM   4799  N NH1 . ARG B 1 175 ? 9.172   22.187  -37.651  1.00 46.80  ? 168  ARG B NH1 1 
ATOM   4800  N NH2 . ARG B 1 175 ? 10.380  24.117  -37.738  1.00 53.04  ? 168  ARG B NH2 1 
ATOM   4801  N N   . GLY B 1 176 ? 6.226   18.387  -43.568  1.00 31.29  ? 169  GLY B N   1 
ATOM   4802  C CA  . GLY B 1 176 ? 5.888   17.461  -44.664  1.00 30.00  ? 169  GLY B CA  1 
ATOM   4803  C C   . GLY B 1 176 ? 6.814   16.262  -44.749  1.00 30.38  ? 169  GLY B C   1 
ATOM   4804  O O   . GLY B 1 176 ? 6.873   15.668  -45.822  1.00 34.18  ? 169  GLY B O   1 
ATOM   4805  N N   . LYS B 1 177 ? 7.493   15.878  -43.669  1.00 29.53  ? 170  LYS B N   1 
ATOM   4806  C CA  . LYS B 1 177 ? 8.436   14.727  -43.671  1.00 28.54  ? 170  LYS B CA  1 
ATOM   4807  C C   . LYS B 1 177 ? 7.957   13.668  -42.682  1.00 26.95  ? 170  LYS B C   1 
ATOM   4808  O O   . LYS B 1 177 ? 7.638   14.013  -41.538  1.00 23.52  ? 170  LYS B O   1 
ATOM   4809  C CB  . LYS B 1 177 ? 9.854   15.183  -43.333  1.00 28.44  ? 170  LYS B CB  1 
ATOM   4810  C CG  . LYS B 1 177 ? 10.425  16.241  -44.258  1.00 30.28  ? 170  LYS B CG  1 
ATOM   4811  C CD  . LYS B 1 177 ? 11.795  16.733  -43.879  1.00 29.50  ? 170  LYS B CD  1 
ATOM   4812  C CE  . LYS B 1 177 ? 12.408  17.611  -44.947  1.00 31.07  ? 170  LYS B CE  1 
ATOM   4813  N NZ  . LYS B 1 177 ? 13.723  18.146  -44.524  1.00 32.86  ? 170  LYS B NZ  1 
ATOM   4814  N N   . PHE B 1 178 ? 7.921   12.415  -43.126  1.00 29.05  ? 171  PHE B N   1 
ATOM   4815  C CA  . PHE B 1 178 ? 7.268   11.293  -42.401  1.00 30.09  ? 171  PHE B CA  1 
ATOM   4816  C C   . PHE B 1 178 ? 8.127   10.022  -42.437  1.00 29.52  ? 171  PHE B C   1 
ATOM   4817  O O   . PHE B 1 178 ? 7.831   9.099   -41.646  1.00 29.55  ? 171  PHE B O   1 
ATOM   4818  C CB  . PHE B 1 178 ? 5.887   11.021  -43.002  1.00 31.78  ? 171  PHE B CB  1 
ATOM   4819  C CG  . PHE B 1 178 ? 4.959   12.210  -42.977  1.00 33.57  ? 171  PHE B CG  1 
ATOM   4820  C CD1 . PHE B 1 178 ? 4.119   12.434  -41.900  1.00 34.73  ? 171  PHE B CD1 1 
ATOM   4821  C CD2 . PHE B 1 178 ? 4.940   13.117  -44.024  1.00 35.92  ? 171  PHE B CD2 1 
ATOM   4822  C CE1 . PHE B 1 178 ? 3.256   13.522  -41.884  1.00 35.07  ? 171  PHE B CE1 1 
ATOM   4823  C CE2 . PHE B 1 178 ? 4.093   14.216  -43.997  1.00 36.09  ? 171  PHE B CE2 1 
ATOM   4824  C CZ  . PHE B 1 178 ? 3.247   14.413  -42.933  1.00 34.81  ? 171  PHE B CZ  1 
ATOM   4825  N N   . THR B 1 179 ? 9.127   9.947   -43.318  1.00 25.77  ? 172  THR B N   1 
ATOM   4826  C CA  . THR B 1 179 ? 9.959   8.732   -43.458  1.00 24.44  ? 172  THR B CA  1 
ATOM   4827  C C   . THR B 1 179 ? 11.036  8.743   -42.359  1.00 24.10  ? 172  THR B C   1 
ATOM   4828  O O   . THR B 1 179 ? 11.542  9.826   -42.001  1.00 25.02  ? 172  THR B O   1 
ATOM   4829  C CB  . THR B 1 179 ? 10.475  8.602   -44.898  1.00 23.67  ? 172  THR B CB  1 
ATOM   4830  O OG1 . THR B 1 179 ? 9.350   8.416   -45.753  1.00 24.29  ? 172  THR B OG1 1 
ATOM   4831  C CG2 . THR B 1 179 ? 11.424  7.441   -45.096  1.00 23.64  ? 172  THR B CG2 1 
ATOM   4832  N N   . PHE B 1 180 ? 11.368  7.567   -41.827  1.00 22.13  ? 173  PHE B N   1 
ATOM   4833  C CA  . PHE B 1 180 ? 12.463  7.355   -40.850  1.00 21.38  ? 173  PHE B CA  1 
ATOM   4834  C C   . PHE B 1 180 ? 13.423  6.320   -41.420  1.00 19.53  ? 173  PHE B C   1 
ATOM   4835  O O   . PHE B 1 180 ? 12.942  5.324   -41.983  1.00 17.23  ? 173  PHE B O   1 
ATOM   4836  C CB  . PHE B 1 180 ? 11.916  6.857   -39.514  1.00 22.57  ? 173  PHE B CB  1 
ATOM   4837  C CG  . PHE B 1 180 ? 11.199  7.914   -38.721  1.00 23.80  ? 173  PHE B CG  1 
ATOM   4838  C CD1 . PHE B 1 180 ? 9.907   8.293   -39.041  1.00 24.28  ? 173  PHE B CD1 1 
ATOM   4839  C CD2 . PHE B 1 180 ? 11.830  8.547   -37.667  1.00 25.83  ? 173  PHE B CD2 1 
ATOM   4840  C CE1 . PHE B 1 180 ? 9.264   9.283   -38.315  1.00 26.22  ? 173  PHE B CE1 1 
ATOM   4841  C CE2 . PHE B 1 180 ? 11.177  9.520   -36.926  1.00 26.58  ? 173  PHE B CE2 1 
ATOM   4842  C CZ  . PHE B 1 180 ? 9.894   9.887   -37.249  1.00 26.79  ? 173  PHE B CZ  1 
ATOM   4843  N N   . ILE B 1 181 ? 14.724  6.557   -41.263  1.00 19.20  ? 174  ILE B N   1 
ATOM   4844  C CA  . ILE B 1 181 ? 15.793  5.603   -41.660  1.00 20.05  ? 174  ILE B CA  1 
ATOM   4845  C C   . ILE B 1 181 ? 16.453  5.058   -40.395  1.00 19.65  ? 174  ILE B C   1 
ATOM   4846  O O   . ILE B 1 181 ? 16.876  5.872   -39.528  1.00 18.85  ? 174  ILE B O   1 
ATOM   4847  C CB  . ILE B 1 181 ? 16.845  6.272   -42.561  1.00 23.44  ? 174  ILE B CB  1 
ATOM   4848  C CG1 . ILE B 1 181 ? 16.212  6.960   -43.770  1.00 26.02  ? 174  ILE B CG1 1 
ATOM   4849  C CG2 . ILE B 1 181 ? 17.931  5.278   -42.975  1.00 23.60  ? 174  ILE B CG2 1 
ATOM   4850  C CD1 . ILE B 1 181 ? 15.290  6.082   -44.572  1.00 27.32  ? 174  ILE B CD1 1 
ATOM   4851  N N   . ALA B 1 182 ? 16.545  3.732   -40.316  1.00 18.50  ? 175  ALA B N   1 
ATOM   4852  C CA  . ALA B 1 182 ? 17.338  3.012   -39.306  1.00 18.51  ? 175  ALA B CA  1 
ATOM   4853  C C   . ALA B 1 182 ? 18.363  2.158   -40.048  1.00 17.56  ? 175  ALA B C   1 
ATOM   4854  O O   . ALA B 1 182 ? 18.420  2.269   -41.287  1.00 18.77  ? 175  ALA B O   1 
ATOM   4855  C CB  . ALA B 1 182 ? 16.400  2.204   -38.444  1.00 18.98  ? 175  ALA B CB  1 
ATOM   4856  N N   . THR B 1 183 ? 19.142  1.358   -39.329  1.00 16.03  ? 176  THR B N   1 
ATOM   4857  C CA  . THR B 1 183 ? 20.195  0.508   -39.917  1.00 16.72  ? 176  THR B CA  1 
ATOM   4858  C C   . THR B 1 183 ? 19.872  -0.951  -39.628  1.00 16.29  ? 176  THR B C   1 
ATOM   4859  O O   . THR B 1 183 ? 19.300  -1.210  -38.622  1.00 15.45  ? 176  THR B O   1 
ATOM   4860  C CB  . THR B 1 183 ? 21.564  0.965   -39.391  1.00 18.64  ? 176  THR B CB  1 
ATOM   4861  O OG1 . THR B 1 183 ? 21.727  0.698   -37.988  1.00 18.43  ? 176  THR B OG1 1 
ATOM   4862  C CG2 . THR B 1 183 ? 21.779  2.446   -39.632  1.00 19.47  ? 176  THR B CG2 1 
ATOM   4863  N N   . SER B 1 184 ? 20.224  -1.865  -40.517  1.00 18.72  ? 177  SER B N   1 
ATOM   4864  C CA  . SER B 1 184 ? 20.135  -3.329  -40.273  1.00 21.09  ? 177  SER B CA  1 
ATOM   4865  C C   . SER B 1 184 ? 21.097  -3.683  -39.138  1.00 23.10  ? 177  SER B C   1 
ATOM   4866  O O   . SER B 1 184 ? 22.117  -2.961  -38.980  1.00 22.45  ? 177  SER B O   1 
ATOM   4867  C CB  . SER B 1 184 ? 20.436  -4.137  -41.506  1.00 22.27  ? 177  SER B CB  1 
ATOM   4868  O OG  . SER B 1 184 ? 21.646  -3.709  -42.110  1.00 22.07  ? 177  SER B OG  1 
ATOM   4869  N N   . GLY B 1 185 ? 20.754  -4.722  -38.367  1.00 24.05  ? 178  GLY B N   1 
ATOM   4870  C CA  . GLY B 1 185 ? 21.429  -5.101  -37.110  1.00 23.65  ? 178  GLY B CA  1 
ATOM   4871  C C   . GLY B 1 185 ? 21.045  -4.211  -35.935  1.00 22.66  ? 178  GLY B C   1 
ATOM   4872  O O   . GLY B 1 185 ? 21.425  -4.565  -34.813  1.00 23.78  ? 178  GLY B O   1 
ATOM   4873  N N   . ALA B 1 186 ? 20.322  -3.109  -36.178  1.00 22.29  ? 179  ALA B N   1 
ATOM   4874  C CA  . ALA B 1 186 ? 19.969  -2.080  -35.173  1.00 21.96  ? 179  ALA B CA  1 
ATOM   4875  C C   . ALA B 1 186 ? 18.969  -2.646  -34.148  1.00 20.09  ? 179  ALA B C   1 
ATOM   4876  O O   . ALA B 1 186 ? 18.115  -3.463  -34.510  1.00 20.62  ? 179  ALA B O   1 
ATOM   4877  C CB  . ALA B 1 186 ? 19.425  -0.834  -35.836  1.00 20.68  ? 179  ALA B CB  1 
ATOM   4878  N N   . PHE B 1 187 ? 19.112  -2.246  -32.896  1.00 18.92  ? 180  PHE B N   1 
ATOM   4879  C CA  . PHE B 1 187 ? 18.200  -2.620  -31.801  1.00 18.64  ? 180  PHE B CA  1 
ATOM   4880  C C   . PHE B 1 187 ? 17.844  -1.344  -31.043  1.00 18.54  ? 180  PHE B C   1 
ATOM   4881  O O   . PHE B 1 187 ? 18.765  -0.743  -30.471  1.00 18.28  ? 180  PHE B O   1 
ATOM   4882  C CB  . PHE B 1 187 ? 18.819  -3.672  -30.881  1.00 18.46  ? 180  PHE B CB  1 
ATOM   4883  C CG  . PHE B 1 187 ? 17.800  -4.171  -29.900  1.00 19.22  ? 180  PHE B CG  1 
ATOM   4884  C CD1 . PHE B 1 187 ? 16.835  -5.083  -30.300  1.00 20.34  ? 180  PHE B CD1 1 
ATOM   4885  C CD2 . PHE B 1 187 ? 17.687  -3.606  -28.641  1.00 19.48  ? 180  PHE B CD2 1 
ATOM   4886  C CE1 . PHE B 1 187 ? 15.837  -5.479  -29.420  1.00 20.09  ? 180  PHE B CE1 1 
ATOM   4887  C CE2 . PHE B 1 187 ? 16.686  -4.010  -27.758  1.00 20.49  ? 180  PHE B CE2 1 
ATOM   4888  C CZ  . PHE B 1 187 ? 15.774  -4.956  -28.143  1.00 19.94  ? 180  PHE B CZ  1 
ATOM   4889  N N   . HIS B 1 188 ? 16.564  -0.943  -31.069  1.00 17.98  ? 181  HIS B N   1 
ATOM   4890  C CA  . HIS B 1 188 ? 16.076  0.324   -30.456  1.00 16.86  ? 181  HIS B CA  1 
ATOM   4891  C C   . HIS B 1 188 ? 14.944  0.060   -29.453  1.00 15.99  ? 181  HIS B C   1 
ATOM   4892  O O   . HIS B 1 188 ? 14.331  1.045   -28.954  1.00 14.57  ? 181  HIS B O   1 
ATOM   4893  C CB  . HIS B 1 188 ? 15.680  1.309   -31.557  1.00 16.68  ? 181  HIS B CB  1 
ATOM   4894  C CG  . HIS B 1 188 ? 16.796  1.594   -32.506  1.00 17.08  ? 181  HIS B CG  1 
ATOM   4895  N ND1 . HIS B 1 188 ? 17.931  2.283   -32.098  1.00 16.94  ? 181  HIS B ND1 1 
ATOM   4896  C CD2 . HIS B 1 188 ? 16.964  1.292   -33.822  1.00 17.06  ? 181  HIS B CD2 1 
ATOM   4897  C CE1 . HIS B 1 188 ? 18.743  2.407   -33.125  1.00 16.95  ? 181  HIS B CE1 1 
ATOM   4898  N NE2 . HIS B 1 188 ? 18.189  1.781   -34.191  1.00 17.18  ? 181  HIS B NE2 1 
ATOM   4899  N N   . GLY B 1 189 ? 14.691  -1.210  -29.144  1.00 15.80  ? 182  GLY B N   1 
ATOM   4900  C CA  . GLY B 1 189 ? 13.597  -1.607  -28.245  1.00 17.06  ? 182  GLY B CA  1 
ATOM   4901  C C   . GLY B 1 189 ? 12.522  -2.414  -28.940  1.00 17.49  ? 182  GLY B C   1 
ATOM   4902  O O   . GLY B 1 189 ? 12.602  -2.640  -30.171  1.00 16.67  ? 182  GLY B O   1 
ATOM   4903  N N   . LYS B 1 190 ? 11.502  -2.777  -28.166  1.00 18.93  ? 183  LYS B N   1 
ATOM   4904  C CA  . LYS B 1 190 ? 10.498  -3.806  -28.533  1.00 19.18  ? 183  LYS B CA  1 
ATOM   4905  C C   . LYS B 1 190 ? 9.070   -3.270  -28.385  1.00 18.44  ? 183  LYS B C   1 
ATOM   4906  O O   . LYS B 1 190 ? 8.150   -3.983  -28.779  1.00 18.48  ? 183  LYS B O   1 
ATOM   4907  C CB  . LYS B 1 190 ? 10.754  -5.029  -27.656  1.00 20.74  ? 183  LYS B CB  1 
ATOM   4908  C CG  . LYS B 1 190 ? 12.109  -5.686  -27.859  1.00 20.59  ? 183  LYS B CG  1 
ATOM   4909  C CD  . LYS B 1 190 ? 11.919  -7.138  -28.158  1.00 21.90  ? 183  LYS B CD  1 
ATOM   4910  C CE  . LYS B 1 190 ? 13.188  -7.878  -28.490  1.00 23.42  ? 183  LYS B CE  1 
ATOM   4911  N NZ  . LYS B 1 190 ? 13.614  -8.782  -27.391  1.00 24.80  ? 183  LYS B NZ  1 
ATOM   4912  N N   . SER B 1 191 ? 8.873   -2.060  -27.868  1.00 18.84  ? 184  SER B N   1 
ATOM   4913  C CA  . SER B 1 191 ? 7.567   -1.363  -27.979  1.00 20.12  ? 184  SER B CA  1 
ATOM   4914  C C   . SER B 1 191 ? 7.356   -1.074  -29.456  1.00 19.08  ? 184  SER B C   1 
ATOM   4915  O O   . SER B 1 191 ? 8.365   -0.930  -30.164  1.00 19.51  ? 184  SER B O   1 
ATOM   4916  C CB  . SER B 1 191 ? 7.503   -0.120  -27.151  1.00 20.81  ? 184  SER B CB  1 
ATOM   4917  O OG  . SER B 1 191 ? 8.511   0.782   -27.546  1.00 21.09  ? 184  SER B OG  1 
ATOM   4918  N N   . LEU B 1 192 ? 6.113   -1.034  -29.918  1.00 18.05  ? 185  LEU B N   1 
ATOM   4919  C CA  . LEU B 1 192 ? 5.820   -1.137  -31.373  1.00 17.35  ? 185  LEU B CA  1 
ATOM   4920  C C   . LEU B 1 192 ? 6.356   0.074   -32.142  1.00 15.89  ? 185  LEU B C   1 
ATOM   4921  O O   . LEU B 1 192 ? 6.643   -0.093  -33.327  1.00 17.10  ? 185  LEU B O   1 
ATOM   4922  C CB  . LEU B 1 192 ? 4.313   -1.329  -31.574  1.00 17.71  ? 185  LEU B CB  1 
ATOM   4923  C CG  . LEU B 1 192 ? 3.806   -2.697  -31.116  1.00 18.64  ? 185  LEU B CG  1 
ATOM   4924  C CD1 . LEU B 1 192 ? 2.303   -2.697  -30.931  1.00 20.45  ? 185  LEU B CD1 1 
ATOM   4925  C CD2 . LEU B 1 192 ? 4.204   -3.796  -32.084  1.00 18.44  ? 185  LEU B CD2 1 
ATOM   4926  N N   . GLY B 1 193 ? 6.492   1.246   -31.531  1.00 14.91  ? 186  GLY B N   1 
ATOM   4927  C CA  . GLY B 1 193 ? 7.129   2.393   -32.202  1.00 15.36  ? 186  GLY B CA  1 
ATOM   4928  C C   . GLY B 1 193 ? 8.624   2.153   -32.366  1.00 15.84  ? 186  GLY B C   1 
ATOM   4929  O O   . GLY B 1 193 ? 9.166   2.301   -33.500  1.00 15.62  ? 186  GLY B O   1 
ATOM   4930  N N   . ALA B 1 194 ? 9.262   1.763   -31.272  1.00 15.47  ? 187  ALA B N   1 
ATOM   4931  C CA  . ALA B 1 194 ? 10.692  1.424   -31.218  1.00 17.13  ? 187  ALA B CA  1 
ATOM   4932  C C   . ALA B 1 194 ? 10.971  0.251   -32.155  1.00 16.70  ? 187  ALA B C   1 
ATOM   4933  O O   . ALA B 1 194 ? 11.986  0.309   -32.844  1.00 21.02  ? 187  ALA B O   1 
ATOM   4934  C CB  . ALA B 1 194 ? 11.097  1.113   -29.780  1.00 17.99  ? 187  ALA B CB  1 
ATOM   4935  N N   . LEU B 1 195 ? 10.112  -0.767  -32.178  1.00 15.46  ? 188  LEU B N   1 
ATOM   4936  C CA  . LEU B 1 195 ? 10.372  -2.028  -32.916  1.00 15.02  ? 188  LEU B CA  1 
ATOM   4937  C C   . LEU B 1 195 ? 10.314  -1.762  -34.424  1.00 15.59  ? 188  LEU B C   1 
ATOM   4938  O O   . LEU B 1 195 ? 10.893  -2.552  -35.184  1.00 15.04  ? 188  LEU B O   1 
ATOM   4939  C CB  . LEU B 1 195 ? 9.348   -3.074  -32.484  1.00 14.76  ? 188  LEU B CB  1 
ATOM   4940  C CG  . LEU B 1 195 ? 9.457   -4.426  -33.172  1.00 14.56  ? 188  LEU B CG  1 
ATOM   4941  C CD1 . LEU B 1 195 ? 10.777  -5.083  -32.847  1.00 14.29  ? 188  LEU B CD1 1 
ATOM   4942  C CD2 . LEU B 1 195 ? 8.315   -5.330  -32.727  1.00 14.46  ? 188  LEU B CD2 1 
ATOM   4943  N N   . SER B 1 196 ? 9.646   -0.685  -34.842  1.00 16.65  ? 189  SER B N   1 
ATOM   4944  C CA  . SER B 1 196 ? 9.624   -0.211  -36.255  1.00 17.08  ? 189  SER B CA  1 
ATOM   4945  C C   . SER B 1 196 ? 11.035  0.179   -36.713  1.00 16.41  ? 189  SER B C   1 
ATOM   4946  O O   . SER B 1 196 ? 11.306  0.064   -37.927  1.00 15.49  ? 189  SER B O   1 
ATOM   4947  C CB  . SER B 1 196 ? 8.656   0.929   -36.448  1.00 16.78  ? 189  SER B CB  1 
ATOM   4948  O OG  . SER B 1 196 ? 7.365   0.549   -36.018  1.00 17.65  ? 189  SER B OG  1 
ATOM   4949  N N   . ALA B 1 197 ? 11.888  0.622   -35.783  1.00 16.44  ? 190  ALA B N   1 
ATOM   4950  C CA  . ALA B 1 197 ? 13.309  0.970   -36.050  1.00 17.05  ? 190  ALA B CA  1 
ATOM   4951  C C   . ALA B 1 197 ? 14.219  -0.247  -35.803  1.00 17.57  ? 190  ALA B C   1 
ATOM   4952  O O   . ALA B 1 197 ? 15.153  -0.470  -36.605  1.00 17.91  ? 190  ALA B O   1 
ATOM   4953  C CB  . ALA B 1 197 ? 13.710  2.154   -35.204  1.00 16.79  ? 190  ALA B CB  1 
ATOM   4954  N N   . THR B 1 198 ? 13.962  -1.036  -34.755  1.00 18.03  ? 191  THR B N   1 
ATOM   4955  C CA  . THR B 1 198 ? 14.663  -2.328  -34.520  1.00 19.30  ? 191  THR B CA  1 
ATOM   4956  C C   . THR B 1 198 ? 14.651  -3.105  -35.843  1.00 20.53  ? 191  THR B C   1 
ATOM   4957  O O   . THR B 1 198 ? 13.679  -2.988  -36.585  1.00 22.25  ? 191  THR B O   1 
ATOM   4958  C CB  . THR B 1 198 ? 14.046  -3.060  -33.321  1.00 18.63  ? 191  THR B CB  1 
ATOM   4959  O OG1 . THR B 1 198 ? 14.326  -2.269  -32.163  1.00 18.99  ? 191  THR B OG1 1 
ATOM   4960  C CG2 . THR B 1 198 ? 14.572  -4.467  -33.137  1.00 18.29  ? 191  THR B CG2 1 
ATOM   4961  N N   . ALA B 1 199 ? 15.712  -3.832  -36.161  1.00 21.89  ? 192  ALA B N   1 
ATOM   4962  C CA  . ALA B 1 199 ? 15.949  -4.330  -37.530  1.00 23.10  ? 192  ALA B CA  1 
ATOM   4963  C C   . ALA B 1 199 ? 15.914  -5.854  -37.577  1.00 24.92  ? 192  ALA B C   1 
ATOM   4964  O O   . ALA B 1 199 ? 15.920  -6.356  -38.687  1.00 31.74  ? 192  ALA B O   1 
ATOM   4965  C CB  . ALA B 1 199 ? 17.263  -3.816  -38.062  1.00 23.37  ? 192  ALA B CB  1 
ATOM   4966  N N   . LYS B 1 200 ? 15.915  -6.583  -36.469  1.00 26.02  ? 193  LYS B N   1 
ATOM   4967  C CA  . LYS B 1 200 ? 16.001  -8.056  -36.585  1.00 27.52  ? 193  LYS B CA  1 
ATOM   4968  C C   . LYS B 1 200 ? 14.632  -8.580  -37.002  1.00 26.02  ? 193  LYS B C   1 
ATOM   4969  O O   . LYS B 1 200 ? 13.628  -8.196  -36.373  1.00 22.92  ? 193  LYS B O   1 
ATOM   4970  C CB  . LYS B 1 200 ? 16.500  -8.709  -35.296  1.00 33.87  ? 193  LYS B CB  1 
ATOM   4971  C CG  . LYS B 1 200 ? 16.354  -10.232 -35.208  1.00 40.09  ? 193  LYS B CG  1 
ATOM   4972  C CD  . LYS B 1 200 ? 17.639  -11.066 -35.335  1.00 46.38  ? 193  LYS B CD  1 
ATOM   4973  C CE  . LYS B 1 200 ? 17.882  -11.962 -34.140  1.00 49.47  ? 193  LYS B CE  1 
ATOM   4974  N NZ  . LYS B 1 200 ? 17.654  -11.232 -32.861  1.00 55.05  ? 193  LYS B NZ  1 
ATOM   4975  N N   . SER B 1 201 ? 14.624  -9.429  -38.032  1.00 26.11  ? 194  SER B N   1 
ATOM   4976  C CA  . SER B 1 201 ? 13.428  -10.033 -38.668  1.00 26.03  ? 194  SER B CA  1 
ATOM   4977  C C   . SER B 1 201 ? 12.562  -10.736 -37.627  1.00 24.28  ? 194  SER B C   1 
ATOM   4978  O O   . SER B 1 201 ? 11.364  -10.457 -37.550  1.00 23.10  ? 194  SER B O   1 
ATOM   4979  C CB  . SER B 1 201 ? 13.829  -11.009 -39.734  1.00 26.39  ? 194  SER B CB  1 
ATOM   4980  O OG  . SER B 1 201 ? 12.670  -11.631 -40.265  1.00 30.60  ? 194  SER B OG  1 
ATOM   4981  N N   . THR B 1 202 ? 13.167  -11.659 -36.890  1.00 24.95  ? 195  THR B N   1 
ATOM   4982  C CA  . THR B 1 202 ? 12.509  -12.557 -35.905  1.00 26.22  ? 195  THR B CA  1 
ATOM   4983  C C   . THR B 1 202 ? 11.804  -11.733 -34.820  1.00 23.86  ? 195  THR B C   1 
ATOM   4984  O O   . THR B 1 202 ? 10.843  -12.243 -34.248  1.00 21.31  ? 195  THR B O   1 
ATOM   4985  C CB  . THR B 1 202 ? 13.511  -13.535 -35.273  1.00 29.30  ? 195  THR B CB  1 
ATOM   4986  O OG1 . THR B 1 202 ? 14.359  -12.818 -34.380  1.00 33.13  ? 195  THR B OG1 1 
ATOM   4987  C CG2 . THR B 1 202 ? 14.393  -14.249 -36.279  1.00 30.72  ? 195  THR B CG2 1 
ATOM   4988  N N   . PHE B 1 203 ? 12.237  -10.499 -34.566  1.00 21.26  ? 196  PHE B N   1 
ATOM   4989  C CA  . PHE B 1 203 ? 11.620  -9.605  -33.561  1.00 19.83  ? 196  PHE B CA  1 
ATOM   4990  C C   . PHE B 1 203 ? 10.459  -8.809  -34.164  1.00 17.21  ? 196  PHE B C   1 
ATOM   4991  O O   . PHE B 1 203 ? 9.676   -8.283  -33.386  1.00 16.21  ? 196  PHE B O   1 
ATOM   4992  C CB  . PHE B 1 203 ? 12.681  -8.679  -32.967  1.00 20.59  ? 196  PHE B CB  1 
ATOM   4993  C CG  . PHE B 1 203 ? 13.653  -9.347  -32.028  1.00 23.25  ? 196  PHE B CG  1 
ATOM   4994  C CD1 . PHE B 1 203 ? 13.406  -10.612 -31.506  1.00 25.16  ? 196  PHE B CD1 1 
ATOM   4995  C CD2 . PHE B 1 203 ? 14.823  -8.704  -31.660  1.00 23.89  ? 196  PHE B CD2 1 
ATOM   4996  C CE1 . PHE B 1 203 ? 14.305  -11.211 -30.630  1.00 26.08  ? 196  PHE B CE1 1 
ATOM   4997  C CE2 . PHE B 1 203 ? 15.720  -9.308  -30.791  1.00 25.38  ? 196  PHE B CE2 1 
ATOM   4998  C CZ  . PHE B 1 203 ? 15.466  -10.563 -30.279  1.00 26.30  ? 196  PHE B CZ  1 
ATOM   4999  N N   . ARG B 1 204 ? 10.353  -8.723  -35.484  1.00 17.31  ? 197  ARG B N   1 
ATOM   5000  C CA  . ARG B 1 204 ? 9.422   -7.784  -36.177  1.00 19.39  ? 197  ARG B CA  1 
ATOM   5001  C C   . ARG B 1 204 ? 8.259   -8.521  -36.853  1.00 19.48  ? 197  ARG B C   1 
ATOM   5002  O O   . ARG B 1 204 ? 7.142   -8.011  -36.769  1.00 21.12  ? 197  ARG B O   1 
ATOM   5003  C CB  . ARG B 1 204 ? 10.162  -6.944  -37.214  1.00 19.05  ? 197  ARG B CB  1 
ATOM   5004  C CG  . ARG B 1 204 ? 11.152  -5.959  -36.618  1.00 19.95  ? 197  ARG B CG  1 
ATOM   5005  C CD  . ARG B 1 204 ? 12.213  -5.566  -37.631  1.00 19.62  ? 197  ARG B CD  1 
ATOM   5006  N NE  . ARG B 1 204 ? 11.640  -5.104  -38.893  1.00 21.31  ? 197  ARG B NE  1 
ATOM   5007  C CZ  . ARG B 1 204 ? 11.155  -3.877  -39.129  1.00 21.61  ? 197  ARG B CZ  1 
ATOM   5008  N NH1 . ARG B 1 204 ? 11.204  -2.920  -38.207  1.00 22.13  ? 197  ARG B NH1 1 
ATOM   5009  N NH2 . ARG B 1 204 ? 10.665  -3.611  -40.326  1.00 20.22  ? 197  ARG B NH2 1 
ATOM   5010  N N   . LYS B 1 205 ? 8.529   -9.653  -37.503  1.00 20.54  ? 198  LYS B N   1 
ATOM   5011  C CA  . LYS B 1 205 ? 7.597   -10.318 -38.456  1.00 21.82  ? 198  LYS B CA  1 
ATOM   5012  C C   . LYS B 1 205 ? 6.266   -10.614 -37.767  1.00 19.01  ? 198  LYS B C   1 
ATOM   5013  O O   . LYS B 1 205 ? 5.215   -10.277 -38.298  1.00 18.12  ? 198  LYS B O   1 
ATOM   5014  C CB  . LYS B 1 205 ? 8.198   -11.580 -39.095  1.00 24.58  ? 198  LYS B CB  1 
ATOM   5015  C CG  . LYS B 1 205 ? 8.883   -11.361 -40.432  1.00 29.15  ? 198  LYS B CG  1 
ATOM   5016  C CD  . LYS B 1 205 ? 9.677   -12.571 -40.908  1.00 33.72  ? 198  LYS B CD  1 
ATOM   5017  C CE  . LYS B 1 205 ? 8.822   -13.595 -41.623  1.00 34.89  ? 198  LYS B CE  1 
ATOM   5018  N NZ  . LYS B 1 205 ? 8.239   -13.000 -42.840  1.00 37.15  ? 198  LYS B NZ  1 
ATOM   5019  N N   . PRO B 1 206 ? 6.244   -11.229 -36.563  1.00 17.36  ? 199  PRO B N   1 
ATOM   5020  C CA  . PRO B 1 206 ? 4.972   -11.549 -35.903  1.00 16.58  ? 199  PRO B CA  1 
ATOM   5021  C C   . PRO B 1 206 ? 4.052   -10.337 -35.662  1.00 15.49  ? 199  PRO B C   1 
ATOM   5022  O O   . PRO B 1 206 ? 2.849   -10.517 -35.585  1.00 14.72  ? 199  PRO B O   1 
ATOM   5023  C CB  . PRO B 1 206 ? 5.423   -12.189 -34.581  1.00 16.47  ? 199  PRO B CB  1 
ATOM   5024  C CG  . PRO B 1 206 ? 6.824   -12.705 -34.861  1.00 16.23  ? 199  PRO B CG  1 
ATOM   5025  C CD  . PRO B 1 206 ? 7.412   -11.667 -35.784  1.00 16.01  ? 199  PRO B CD  1 
ATOM   5026  N N   . PHE B 1 207 ? 4.635   -9.139  -35.587  1.00 15.38  ? 200  PHE B N   1 
ATOM   5027  C CA  . PHE B 1 207 ? 3.996   -7.906  -35.065  1.00 16.02  ? 200  PHE B CA  1 
ATOM   5028  C C   . PHE B 1 207 ? 3.726   -6.920  -36.204  1.00 17.02  ? 200  PHE B C   1 
ATOM   5029  O O   . PHE B 1 207 ? 3.131   -5.855  -35.984  1.00 18.14  ? 200  PHE B O   1 
ATOM   5030  C CB  . PHE B 1 207 ? 4.873   -7.345  -33.946  1.00 15.67  ? 200  PHE B CB  1 
ATOM   5031  C CG  . PHE B 1 207 ? 5.251   -8.398  -32.925  1.00 15.18  ? 200  PHE B CG  1 
ATOM   5032  C CD1 . PHE B 1 207 ? 4.305   -8.942  -32.069  1.00 14.82  ? 200  PHE B CD1 1 
ATOM   5033  C CD2 . PHE B 1 207 ? 6.540   -8.891  -32.855  1.00 14.91  ? 200  PHE B CD2 1 
ATOM   5034  C CE1 . PHE B 1 207 ? 4.640   -9.948  -31.175  1.00 14.83  ? 200  PHE B CE1 1 
ATOM   5035  C CE2 . PHE B 1 207 ? 6.881   -9.891  -31.959  1.00 14.88  ? 200  PHE B CE2 1 
ATOM   5036  C CZ  . PHE B 1 207 ? 5.934   -10.415 -31.115  1.00 14.85  ? 200  PHE B CZ  1 
ATOM   5037  N N   . MET B 1 208 ? 4.098   -7.274  -37.419  1.00 17.92  ? 201  MET B N   1 
ATOM   5038  C CA  . MET B 1 208 ? 3.741   -6.450  -38.595  1.00 20.60  ? 201  MET B CA  1 
ATOM   5039  C C   . MET B 1 208 ? 2.245   -6.567  -38.838  1.00 22.62  ? 201  MET B C   1 
ATOM   5040  O O   . MET B 1 208 ? 1.608   -7.550  -38.455  1.00 25.53  ? 201  MET B O   1 
ATOM   5041  C CB  . MET B 1 208 ? 4.508   -6.913  -39.829  1.00 21.58  ? 201  MET B CB  1 
ATOM   5042  C CG  . MET B 1 208 ? 5.996   -6.686  -39.703  1.00 20.97  ? 201  MET B CG  1 
ATOM   5043  S SD  . MET B 1 208 ? 6.838   -7.466  -41.068  1.00 21.87  ? 201  MET B SD  1 
ATOM   5044  C CE  . MET B 1 208 ? 8.536   -7.121  -40.608  1.00 23.60  ? 201  MET B CE  1 
ATOM   5045  N N   . PRO B 1 209 ? 1.612   -5.535  -39.431  1.00 23.23  ? 202  PRO B N   1 
ATOM   5046  C CA  . PRO B 1 209 ? 2.293   -4.306  -39.840  1.00 20.72  ? 202  PRO B CA  1 
ATOM   5047  C C   . PRO B 1 209 ? 2.657   -3.341  -38.710  1.00 19.09  ? 202  PRO B C   1 
ATOM   5048  O O   . PRO B 1 209 ? 1.828   -3.071  -37.855  1.00 18.35  ? 202  PRO B O   1 
ATOM   5049  C CB  . PRO B 1 209 ? 1.253   -3.608  -40.719  1.00 22.44  ? 202  PRO B CB  1 
ATOM   5050  C CG  . PRO B 1 209 ? -0.066  -4.074  -40.158  1.00 24.30  ? 202  PRO B CG  1 
ATOM   5051  C CD  . PRO B 1 209 ? 0.174   -5.513  -39.742  1.00 24.40  ? 202  PRO B CD  1 
ATOM   5052  N N   . LEU B 1 210 ? 3.886   -2.836  -38.771  1.00 17.30  ? 203  LEU B N   1 
ATOM   5053  C CA  . LEU B 1 210 ? 4.471   -1.878  -37.812  1.00 16.16  ? 203  LEU B CA  1 
ATOM   5054  C C   . LEU B 1 210 ? 4.193   -0.456  -38.299  1.00 15.93  ? 203  LEU B C   1 
ATOM   5055  O O   . LEU B 1 210 ? 3.304   -0.290  -39.123  1.00 15.47  ? 203  LEU B O   1 
ATOM   5056  C CB  . LEU B 1 210 ? 5.960   -2.198  -37.694  1.00 15.97  ? 203  LEU B CB  1 
ATOM   5057  C CG  . LEU B 1 210 ? 6.263   -3.562  -37.074  1.00 15.81  ? 203  LEU B CG  1 
ATOM   5058  C CD1 . LEU B 1 210 ? 7.757   -3.841  -37.030  1.00 15.52  ? 203  LEU B CD1 1 
ATOM   5059  C CD2 . LEU B 1 210 ? 5.670   -3.674  -35.666  1.00 15.58  ? 203  LEU B CD2 1 
ATOM   5060  N N   . LEU B 1 211 ? 4.846   0.551   -37.728  1.00 17.04  ? 204  LEU B N   1 
ATOM   5061  C CA  . LEU B 1 211 ? 4.654   1.941   -38.191  1.00 18.31  ? 204  LEU B CA  1 
ATOM   5062  C C   . LEU B 1 211 ? 5.030   1.960   -39.660  1.00 21.30  ? 204  LEU B C   1 
ATOM   5063  O O   . LEU B 1 211 ? 6.069   1.424   -40.042  1.00 21.03  ? 204  LEU B O   1 
ATOM   5064  C CB  . LEU B 1 211 ? 5.524   2.931   -37.423  1.00 16.59  ? 204  LEU B CB  1 
ATOM   5065  C CG  . LEU B 1 211 ? 5.095   3.216   -36.002  1.00 16.95  ? 204  LEU B CG  1 
ATOM   5066  C CD1 . LEU B 1 211 ? 6.056   4.180   -35.346  1.00 17.77  ? 204  LEU B CD1 1 
ATOM   5067  C CD2 . LEU B 1 211 ? 3.680   3.762   -35.944  1.00 17.64  ? 204  LEU B CD2 1 
ATOM   5068  N N   . PRO B 1 212 ? 4.227   2.621   -40.514  1.00 23.79  ? 205  PRO B N   1 
ATOM   5069  C CA  . PRO B 1 212 ? 4.642   2.838   -41.894  1.00 24.69  ? 205  PRO B CA  1 
ATOM   5070  C C   . PRO B 1 212 ? 5.771   3.883   -41.957  1.00 24.44  ? 205  PRO B C   1 
ATOM   5071  O O   . PRO B 1 212 ? 5.967   4.655   -41.042  1.00 25.07  ? 205  PRO B O   1 
ATOM   5072  C CB  . PRO B 1 212 ? 3.337   3.258   -42.604  1.00 25.91  ? 205  PRO B CB  1 
ATOM   5073  C CG  . PRO B 1 212 ? 2.408   3.767   -41.510  1.00 25.27  ? 205  PRO B CG  1 
ATOM   5074  C CD  . PRO B 1 212 ? 2.912   3.207   -40.192  1.00 26.00  ? 205  PRO B CD  1 
ATOM   5075  N N   . GLY B 1 213 ? 6.532   3.858   -43.038  1.00 24.27  ? 206  GLY B N   1 
ATOM   5076  C CA  . GLY B 1 213 ? 7.500   4.921   -43.357  1.00 23.84  ? 206  GLY B CA  1 
ATOM   5077  C C   . GLY B 1 213 ? 8.868   4.644   -42.781  1.00 22.85  ? 206  GLY B C   1 
ATOM   5078  O O   . GLY B 1 213 ? 9.649   5.613   -42.713  1.00 22.60  ? 206  GLY B O   1 
ATOM   5079  N N   . PHE B 1 214 ? 9.150   3.397   -42.370  1.00 22.67  ? 207  PHE B N   1 
ATOM   5080  C CA  . PHE B 1 214 ? 10.453  2.990   -41.761  1.00 22.77  ? 207  PHE B CA  1 
ATOM   5081  C C   . PHE B 1 214 ? 11.228  2.160   -42.791  1.00 23.33  ? 207  PHE B C   1 
ATOM   5082  O O   . PHE B 1 214 ? 10.689  1.151   -43.313  1.00 21.73  ? 207  PHE B O   1 
ATOM   5083  C CB  . PHE B 1 214 ? 10.269  2.277   -40.417  1.00 22.16  ? 207  PHE B CB  1 
ATOM   5084  C CG  . PHE B 1 214 ? 10.039  3.216   -39.254  1.00 22.79  ? 207  PHE B CG  1 
ATOM   5085  C CD1 . PHE B 1 214 ? 8.833   3.912   -39.117  1.00 22.15  ? 207  PHE B CD1 1 
ATOM   5086  C CD2 . PHE B 1 214 ? 11.029  3.419   -38.298  1.00 22.54  ? 207  PHE B CD2 1 
ATOM   5087  C CE1 . PHE B 1 214 ? 8.635   4.789   -38.059  1.00 21.81  ? 207  PHE B CE1 1 
ATOM   5088  C CE2 . PHE B 1 214 ? 10.819  4.296   -37.237  1.00 21.72  ? 207  PHE B CE2 1 
ATOM   5089  C CZ  . PHE B 1 214 ? 9.626   4.977   -37.117  1.00 20.76  ? 207  PHE B CZ  1 
ATOM   5090  N N   A ARG B 1 215 ? 12.458  2.600   -43.088  0.45 22.98  ? 208  ARG B N   1 
ATOM   5091  N N   B ARG B 1 215 ? 12.459  2.599   -43.086  0.55 22.53  ? 208  ARG B N   1 
ATOM   5092  C CA  A ARG B 1 215 ? 13.374  1.987   -44.081  0.45 22.85  ? 208  ARG B CA  1 
ATOM   5093  C CA  B ARG B 1 215 ? 13.371  1.992   -44.086  0.55 22.10  ? 208  ARG B CA  1 
ATOM   5094  C C   A ARG B 1 215 ? 14.741  1.772   -43.424  0.45 22.42  ? 208  ARG B C   1 
ATOM   5095  C C   B ARG B 1 215 ? 14.740  1.772   -43.429  0.55 21.94  ? 208  ARG B C   1 
ATOM   5096  O O   A ARG B 1 215 ? 15.142  2.609   -42.582  0.45 21.79  ? 208  ARG B O   1 
ATOM   5097  O O   B ARG B 1 215 ? 15.144  2.610   -42.588  0.55 21.25  ? 208  ARG B O   1 
ATOM   5098  C CB  A ARG B 1 215 ? 13.529  2.890   -45.308  0.45 23.13  ? 208  ARG B CB  1 
ATOM   5099  C CB  B ARG B 1 215 ? 13.505  2.911   -45.305  0.55 21.83  ? 208  ARG B CB  1 
ATOM   5100  C CG  A ARG B 1 215 ? 12.235  3.411   -45.907  0.45 23.90  ? 208  ARG B CG  1 
ATOM   5101  C CG  B ARG B 1 215 ? 12.231  3.175   -46.094  0.55 22.20  ? 208  ARG B CG  1 
ATOM   5102  C CD  A ARG B 1 215 ? 11.372  2.352   -46.574  0.45 24.84  ? 208  ARG B CD  1 
ATOM   5103  C CD  B ARG B 1 215 ? 12.438  4.330   -47.069  0.55 22.80  ? 208  ARG B CD  1 
ATOM   5104  N NE  A ARG B 1 215 ? 10.159  2.977   -47.081  0.45 25.58  ? 208  ARG B NE  1 
ATOM   5105  N NE  B ARG B 1 215 ? 11.673  4.324   -48.330  0.55 21.68  ? 208  ARG B NE  1 
ATOM   5106  C CZ  A ARG B 1 215 ? 8.949   2.814   -46.559  0.45 26.06  ? 208  ARG B CZ  1 
ATOM   5107  C CZ  B ARG B 1 215 ? 10.462  4.848   -48.484  0.55 21.26  ? 208  ARG B CZ  1 
ATOM   5108  N NH1 A ARG B 1 215 ? 8.763   1.994   -45.537  0.45 25.28  ? 208  ARG B NH1 1 
ATOM   5109  N NH1 B ARG B 1 215 ? 9.856   5.431   -47.461  0.55 22.34  ? 208  ARG B NH1 1 
ATOM   5110  N NH2 A ARG B 1 215 ? 7.920   3.449   -47.088  0.45 26.86  ? 208  ARG B NH2 1 
ATOM   5111  N NH2 B ARG B 1 215 ? 9.858   4.791   -49.653  0.55 20.57  ? 208  ARG B NH2 1 
ATOM   5112  N N   . HIS B 1 216 ? 15.443  0.712   -43.828  1.00 22.39  ? 209  HIS B N   1 
ATOM   5113  C CA  . HIS B 1 216 ? 16.740  0.307   -43.228  1.00 22.72  ? 209  HIS B CA  1 
ATOM   5114  C C   . HIS B 1 216 ? 17.849  0.341   -44.292  1.00 22.14  ? 209  HIS B C   1 
ATOM   5115  O O   . HIS B 1 216 ? 17.641  -0.165  -45.414  1.00 18.75  ? 209  HIS B O   1 
ATOM   5116  C CB  . HIS B 1 216 ? 16.571  -1.048  -42.531  1.00 23.65  ? 209  HIS B CB  1 
ATOM   5117  C CG  . HIS B 1 216 ? 15.741  -0.978  -41.288  1.00 27.06  ? 209  HIS B CG  1 
ATOM   5118  N ND1 . HIS B 1 216 ? 14.349  -1.049  -41.311  1.00 27.37  ? 209  HIS B ND1 1 
ATOM   5119  C CD2 . HIS B 1 216 ? 16.089  -0.836  -39.990  1.00 25.89  ? 209  HIS B CD2 1 
ATOM   5120  C CE1 . HIS B 1 216 ? 13.887  -0.972  -40.071  1.00 27.29  ? 209  HIS B CE1 1 
ATOM   5121  N NE2 . HIS B 1 216 ? 14.933  -0.830  -39.248  1.00 27.43  ? 209  HIS B NE2 1 
ATOM   5122  N N   . VAL B 1 217 ? 18.999  0.911   -43.919  1.00 22.27  ? 210  VAL B N   1 
ATOM   5123  C CA  . VAL B 1 217 ? 20.260  0.908   -44.715  1.00 21.06  ? 210  VAL B CA  1 
ATOM   5124  C C   . VAL B 1 217 ? 21.293  0.113   -43.922  1.00 22.75  ? 210  VAL B C   1 
ATOM   5125  O O   . VAL B 1 217 ? 21.080  -0.139  -42.735  1.00 21.22  ? 210  VAL B O   1 
ATOM   5126  C CB  . VAL B 1 217 ? 20.704  2.344   -45.052  1.00 19.72  ? 210  VAL B CB  1 
ATOM   5127  C CG1 . VAL B 1 217 ? 19.655  3.047   -45.890  1.00 20.51  ? 210  VAL B CG1 1 
ATOM   5128  C CG2 . VAL B 1 217 ? 21.001  3.178   -43.832  1.00 19.44  ? 210  VAL B CG2 1 
ATOM   5129  N N   . PRO B 1 218 ? 22.391  -0.382  -44.555  1.00 24.28  ? 211  PRO B N   1 
ATOM   5130  C CA  . PRO B 1 218 ? 23.493  -1.014  -43.830  1.00 23.85  ? 211  PRO B CA  1 
ATOM   5131  C C   . PRO B 1 218 ? 24.140  -0.007  -42.877  1.00 22.91  ? 211  PRO B C   1 
ATOM   5132  O O   . PRO B 1 218 ? 24.273  1.171   -43.237  1.00 24.42  ? 211  PRO B O   1 
ATOM   5133  C CB  . PRO B 1 218 ? 24.512  -1.433  -44.906  1.00 24.08  ? 211  PRO B CB  1 
ATOM   5134  C CG  . PRO B 1 218 ? 23.703  -1.480  -46.178  1.00 24.41  ? 211  PRO B CG  1 
ATOM   5135  C CD  . PRO B 1 218 ? 22.615  -0.433  -46.011  1.00 24.84  ? 211  PRO B CD  1 
ATOM   5136  N N   . PHE B 1 219 ? 24.512  -0.492  -41.696  1.00 21.61  ? 212  PHE B N   1 
ATOM   5137  C CA  . PHE B 1 219 ? 25.236  0.283   -40.670  1.00 20.82  ? 212  PHE B CA  1 
ATOM   5138  C C   . PHE B 1 219 ? 26.671  0.491   -41.159  1.00 20.15  ? 212  PHE B C   1 
ATOM   5139  O O   . PHE B 1 219 ? 27.273  -0.484  -41.650  1.00 18.78  ? 212  PHE B O   1 
ATOM   5140  C CB  . PHE B 1 219 ? 25.211  -0.469  -39.339  1.00 20.72  ? 212  PHE B CB  1 
ATOM   5141  C CG  . PHE B 1 219 ? 25.837  0.282   -38.200  1.00 19.12  ? 212  PHE B CG  1 
ATOM   5142  C CD1 . PHE B 1 219 ? 25.249  1.426   -37.710  1.00 19.40  ? 212  PHE B CD1 1 
ATOM   5143  C CD2 . PHE B 1 219 ? 27.021  -0.139  -37.645  1.00 20.36  ? 212  PHE B CD2 1 
ATOM   5144  C CE1 . PHE B 1 219 ? 25.822  2.137   -36.674  1.00 20.37  ? 212  PHE B CE1 1 
ATOM   5145  C CE2 . PHE B 1 219 ? 27.595  0.550   -36.583  1.00 21.05  ? 212  PHE B CE2 1 
ATOM   5146  C CZ  . PHE B 1 219 ? 26.997  1.697   -36.104  1.00 21.39  ? 212  PHE B CZ  1 
ATOM   5147  N N   . GLY B 1 220 ? 27.180  1.717   -41.026  1.00 21.16  ? 213  GLY B N   1 
ATOM   5148  C CA  . GLY B 1 220 ? 28.587  2.075   -41.297  1.00 22.36  ? 213  GLY B CA  1 
ATOM   5149  C C   . GLY B 1 220 ? 28.845  2.283   -42.781  1.00 22.58  ? 213  GLY B C   1 
ATOM   5150  O O   . GLY B 1 220 ? 30.022  2.260   -43.171  1.00 26.86  ? 213  GLY B O   1 
ATOM   5151  N N   . ASN B 1 221 ? 27.783  2.488   -43.578  1.00 23.33  ? 214  ASN B N   1 
ATOM   5152  C CA  . ASN B 1 221 ? 27.811  2.692   -45.053  1.00 20.88  ? 214  ASN B CA  1 
ATOM   5153  C C   . ASN B 1 221 ? 27.154  4.033   -45.385  1.00 20.77  ? 214  ASN B C   1 
ATOM   5154  O O   . ASN B 1 221 ? 25.966  4.033   -45.660  1.00 21.60  ? 214  ASN B O   1 
ATOM   5155  C CB  . ASN B 1 221 ? 27.127  1.532   -45.771  1.00 21.23  ? 214  ASN B CB  1 
ATOM   5156  C CG  . ASN B 1 221 ? 27.198  1.616   -47.285  1.00 21.85  ? 214  ASN B CG  1 
ATOM   5157  O OD1 . ASN B 1 221 ? 27.396  2.674   -47.880  1.00 20.97  ? 214  ASN B OD1 1 
ATOM   5158  N ND2 . ASN B 1 221 ? 27.011  0.485   -47.932  1.00 21.89  ? 214  ASN B ND2 1 
ATOM   5159  N N   . ILE B 1 222 ? 27.919  5.123   -45.366  1.00 22.38  ? 215  ILE B N   1 
ATOM   5160  C CA  . ILE B 1 222 ? 27.419  6.512   -45.594  1.00 24.75  ? 215  ILE B CA  1 
ATOM   5161  C C   . ILE B 1 222 ? 26.819  6.619   -46.997  1.00 26.79  ? 215  ILE B C   1 
ATOM   5162  O O   . ILE B 1 222 ? 25.848  7.383   -47.158  1.00 28.39  ? 215  ILE B O   1 
ATOM   5163  C CB  . ILE B 1 222 ? 28.516  7.581   -45.371  1.00 25.20  ? 215  ILE B CB  1 
ATOM   5164  C CG1 . ILE B 1 222 ? 27.917  8.991   -45.282  1.00 26.49  ? 215  ILE B CG1 1 
ATOM   5165  C CG2 . ILE B 1 222 ? 29.603  7.509   -46.429  1.00 24.08  ? 215  ILE B CG2 1 
ATOM   5166  C CD1 . ILE B 1 222 ? 26.984  9.224   -44.071  1.00 26.74  ? 215  ILE B CD1 1 
ATOM   5167  N N   . GLU B 1 223 ? 27.350  5.897   -47.977  1.00 26.80  ? 216  GLU B N   1 
ATOM   5168  C CA  . GLU B 1 223 ? 26.866  6.057   -49.370  1.00 29.40  ? 216  GLU B CA  1 
ATOM   5169  C C   . GLU B 1 223 ? 25.460  5.466   -49.488  1.00 26.98  ? 216  GLU B C   1 
ATOM   5170  O O   . GLU B 1 223 ? 24.604  6.144   -50.101  1.00 24.53  ? 216  GLU B O   1 
ATOM   5171  C CB  . GLU B 1 223 ? 27.909  5.536   -50.362  1.00 32.54  ? 216  GLU B CB  1 
ATOM   5172  C CG  . GLU B 1 223 ? 29.050  6.537   -50.547  1.00 35.97  ? 216  GLU B CG  1 
ATOM   5173  C CD  . GLU B 1 223 ? 28.587  7.967   -50.838  1.00 40.23  ? 216  GLU B CD  1 
ATOM   5174  O OE1 . GLU B 1 223 ? 27.642  8.108   -51.649  1.00 39.94  ? 216  GLU B OE1 1 
ATOM   5175  O OE2 . GLU B 1 223 ? 29.143  8.945   -50.239  1.00 43.41  ? 216  GLU B OE2 1 
ATOM   5176  N N   . ALA B 1 224 ? 25.221  4.293   -48.893  1.00 25.49  ? 217  ALA B N   1 
ATOM   5177  C CA  . ALA B 1 224 ? 23.899  3.616   -48.857  1.00 25.68  ? 217  ALA B CA  1 
ATOM   5178  C C   . ALA B 1 224 ? 22.857  4.545   -48.219  1.00 24.72  ? 217  ALA B C   1 
ATOM   5179  O O   . ALA B 1 224 ? 21.720  4.617   -48.710  1.00 24.20  ? 217  ALA B O   1 
ATOM   5180  C CB  . ALA B 1 224 ? 24.004  2.324   -48.090  1.00 26.23  ? 217  ALA B CB  1 
ATOM   5181  N N   . MET B 1 225 ? 23.254  5.250   -47.171  1.00 22.89  ? 218  MET B N   1 
ATOM   5182  C CA  . MET B 1 225 ? 22.363  6.178   -46.444  1.00 24.19  ? 218  MET B CA  1 
ATOM   5183  C C   . MET B 1 225 ? 22.091  7.404   -47.315  1.00 22.77  ? 218  MET B C   1 
ATOM   5184  O O   . MET B 1 225 ? 20.947  7.829   -47.355  1.00 22.59  ? 218  MET B O   1 
ATOM   5185  C CB  . MET B 1 225 ? 22.956  6.610   -45.099  1.00 25.15  ? 218  MET B CB  1 
ATOM   5186  C CG  . MET B 1 225 ? 21.917  7.245   -44.184  1.00 26.98  ? 218  MET B CG  1 
ATOM   5187  S SD  . MET B 1 225 ? 22.608  7.814   -42.642  1.00 30.17  ? 218  MET B SD  1 
ATOM   5188  C CE  . MET B 1 225 ? 22.362  6.359   -41.618  1.00 29.71  ? 218  MET B CE  1 
ATOM   5189  N N   . ARG B 1 226 ? 23.105  7.985   -47.944  1.00 24.47  ? 219  ARG B N   1 
ATOM   5190  C CA  . ARG B 1 226 ? 22.935  9.143   -48.867  1.00 26.21  ? 219  ARG B CA  1 
ATOM   5191  C C   . ARG B 1 226 ? 21.891  8.778   -49.922  1.00 24.28  ? 219  ARG B C   1 
ATOM   5192  O O   . ARG B 1 226 ? 20.938  9.561   -50.138  1.00 23.67  ? 219  ARG B O   1 
ATOM   5193  C CB  . ARG B 1 226 ? 24.259  9.504   -49.554  1.00 28.31  ? 219  ARG B CB  1 
ATOM   5194  C CG  . ARG B 1 226 ? 24.124  10.570  -50.629  1.00 31.25  ? 219  ARG B CG  1 
ATOM   5195  C CD  . ARG B 1 226 ? 25.469  11.167  -51.016  1.00 34.76  ? 219  ARG B CD  1 
ATOM   5196  N NE  . ARG B 1 226 ? 25.949  12.122  -50.031  1.00 37.77  ? 219  ARG B NE  1 
ATOM   5197  C CZ  . ARG B 1 226 ? 25.555  13.393  -49.927  1.00 40.86  ? 219  ARG B CZ  1 
ATOM   5198  N NH1 . ARG B 1 226 ? 24.715  13.920  -50.797  1.00 38.58  ? 219  ARG B NH1 1 
ATOM   5199  N NH2 . ARG B 1 226 ? 26.020  14.154  -48.949  1.00 50.53  ? 219  ARG B NH2 1 
ATOM   5200  N N   . THR B 1 227 ? 22.080  7.613   -50.538  1.00 23.73  ? 220  THR B N   1 
ATOM   5201  C CA  . THR B 1 227 ? 21.186  7.053   -51.575  1.00 25.24  ? 220  THR B CA  1 
ATOM   5202  C C   . THR B 1 227 ? 19.745  7.083   -51.044  1.00 25.40  ? 220  THR B C   1 
ATOM   5203  O O   . THR B 1 227 ? 18.854  7.602   -51.753  1.00 27.19  ? 220  THR B O   1 
ATOM   5204  C CB  . THR B 1 227 ? 21.633  5.643   -51.987  1.00 24.80  ? 220  THR B CB  1 
ATOM   5205  O OG1 . THR B 1 227 ? 22.864  5.777   -52.699  1.00 22.66  ? 220  THR B OG1 1 
ATOM   5206  C CG2 . THR B 1 227 ? 20.596  4.918   -52.827  1.00 25.16  ? 220  THR B CG2 1 
ATOM   5207  N N   . ALA B 1 228 ? 19.535  6.539   -49.851  1.00 22.29  ? 221  ALA B N   1 
ATOM   5208  C CA  . ALA B 1 228 ? 18.202  6.339   -49.266  1.00 22.27  ? 221  ALA B CA  1 
ATOM   5209  C C   . ALA B 1 228 ? 17.553  7.705   -49.073  1.00 22.75  ? 221  ALA B C   1 
ATOM   5210  O O   . ALA B 1 228 ? 16.358  7.826   -49.425  1.00 23.74  ? 221  ALA B O   1 
ATOM   5211  C CB  . ALA B 1 228 ? 18.298  5.563   -47.977  1.00 21.78  ? 221  ALA B CB  1 
ATOM   5212  N N   . LEU B 1 229 ? 18.310  8.691   -48.575  1.00 22.22  ? 222  LEU B N   1 
ATOM   5213  C CA  . LEU B 1 229 ? 17.789  10.061  -48.307  1.00 23.62  ? 222  LEU B CA  1 
ATOM   5214  C C   . LEU B 1 229 ? 17.428  10.723  -49.627  1.00 24.59  ? 222  LEU B C   1 
ATOM   5215  O O   . LEU B 1 229 ? 16.367  11.389  -49.704  1.00 23.03  ? 222  LEU B O   1 
ATOM   5216  C CB  . LEU B 1 229 ? 18.825  10.904  -47.561  1.00 24.43  ? 222  LEU B CB  1 
ATOM   5217  C CG  . LEU B 1 229 ? 18.574  11.006  -46.059  1.00 25.09  ? 222  LEU B CG  1 
ATOM   5218  C CD1 . LEU B 1 229 ? 18.612  9.634   -45.398  1.00 24.91  ? 222  LEU B CD1 1 
ATOM   5219  C CD2 . LEU B 1 229 ? 19.584  11.938  -45.430  1.00 28.11  ? 222  LEU B CD2 1 
ATOM   5220  N N   . ASN B 1 230 ? 18.306  10.538  -50.606  1.00 23.77  ? 223  ASN B N   1 
ATOM   5221  C CA  . ASN B 1 230 ? 18.170  11.181  -51.926  1.00 25.18  ? 223  ASN B CA  1 
ATOM   5222  C C   . ASN B 1 230 ? 16.951  10.611  -52.663  1.00 23.00  ? 223  ASN B C   1 
ATOM   5223  O O   . ASN B 1 230 ? 16.185  11.415  -53.199  1.00 20.97  ? 223  ASN B O   1 
ATOM   5224  C CB  . ASN B 1 230 ? 19.455  11.036  -52.736  1.00 26.85  ? 223  ASN B CB  1 
ATOM   5225  C CG  . ASN B 1 230 ? 19.517  12.109  -53.789  1.00 29.37  ? 223  ASN B CG  1 
ATOM   5226  O OD1 . ASN B 1 230 ? 19.257  13.279  -53.516  1.00 30.08  ? 223  ASN B OD1 1 
ATOM   5227  N ND2 . ASN B 1 230 ? 19.799  11.708  -55.009  1.00 34.12  ? 223  ASN B ND2 1 
ATOM   5228  N N   . GLU B 1 231 ? 16.807  9.281   -52.676  1.00 23.28  ? 224  GLU B N   1 
ATOM   5229  C CA  . GLU B 1 231 ? 15.708  8.543   -53.357  1.00 24.45  ? 224  GLU B CA  1 
ATOM   5230  C C   . GLU B 1 231 ? 14.390  8.905   -52.679  1.00 24.45  ? 224  GLU B C   1 
ATOM   5231  O O   . GLU B 1 231 ? 13.416  9.122   -53.400  1.00 27.57  ? 224  GLU B O   1 
ATOM   5232  C CB  . GLU B 1 231 ? 15.945  7.030   -53.352  1.00 26.21  ? 224  GLU B CB  1 
ATOM   5233  C CG  . GLU B 1 231 ? 17.152  6.604   -54.196  1.00 30.24  ? 224  GLU B CG  1 
ATOM   5234  C CD  . GLU B 1 231 ? 17.082  6.802   -55.716  1.00 32.61  ? 224  GLU B CD  1 
ATOM   5235  O OE1 . GLU B 1 231 ? 16.128  6.281   -56.350  1.00 31.80  ? 224  GLU B OE1 1 
ATOM   5236  O OE2 . GLU B 1 231 ? 18.005  7.442   -56.289  1.00 33.58  ? 224  GLU B OE2 1 
ATOM   5237  N N   . CYS B 1 232 ? 14.367  9.002   -51.351  1.00 23.16  ? 225  CYS B N   1 
ATOM   5238  C CA  . CYS B 1 232 ? 13.173  9.419   -50.580  1.00 23.76  ? 225  CYS B CA  1 
ATOM   5239  C C   . CYS B 1 232 ? 12.777  10.852  -50.962  1.00 23.66  ? 225  CYS B C   1 
ATOM   5240  O O   . CYS B 1 232 ? 11.554  11.110  -51.108  1.00 21.06  ? 225  CYS B O   1 
ATOM   5241  C CB  . CYS B 1 232 ? 13.395  9.263   -49.081  1.00 25.46  ? 225  CYS B CB  1 
ATOM   5242  S SG  . CYS B 1 232 ? 13.280  7.536   -48.542  1.00 26.60  ? 225  CYS B SG  1 
ATOM   5243  N N   . LYS B 1 233 ? 13.758  11.735  -51.167  1.00 25.09  ? 226  LYS B N   1 
ATOM   5244  C CA  . LYS B 1 233 ? 13.528  13.143  -51.597  1.00 26.87  ? 226  LYS B CA  1 
ATOM   5245  C C   . LYS B 1 233 ? 12.915  13.170  -53.004  1.00 24.60  ? 226  LYS B C   1 
ATOM   5246  O O   . LYS B 1 233 ? 11.911  13.904  -53.219  1.00 21.54  ? 226  LYS B O   1 
ATOM   5247  C CB  . LYS B 1 233 ? 14.848  13.912  -51.574  1.00 28.79  ? 226  LYS B CB  1 
ATOM   5248  C CG  . LYS B 1 233 ? 14.768  15.342  -52.076  1.00 31.63  ? 226  LYS B CG  1 
ATOM   5249  C CD  . LYS B 1 233 ? 16.122  16.024  -52.119  1.00 36.44  ? 226  LYS B CD  1 
ATOM   5250  C CE  . LYS B 1 233 ? 16.088  17.488  -51.712  1.00 41.29  ? 226  LYS B CE  1 
ATOM   5251  N NZ  . LYS B 1 233 ? 15.506  18.364  -52.760  1.00 45.14  ? 226  LYS B NZ  1 
ATOM   5252  N N   . LYS B 1 234 ? 13.492  12.395  -53.923  1.00 23.69  ? 227  LYS B N   1 
ATOM   5253  C CA  . LYS B 1 234 ? 13.027  12.303  -55.331  1.00 24.27  ? 227  LYS B CA  1 
ATOM   5254  C C   . LYS B 1 234 ? 11.553  11.867  -55.385  1.00 23.44  ? 227  LYS B C   1 
ATOM   5255  O O   . LYS B 1 234 ? 10.824  12.450  -56.205  1.00 23.48  ? 227  LYS B O   1 
ATOM   5256  C CB  . LYS B 1 234 ? 13.897  11.338  -56.138  1.00 25.79  ? 227  LYS B CB  1 
ATOM   5257  C CG  . LYS B 1 234 ? 15.344  11.766  -56.318  1.00 28.15  ? 227  LYS B CG  1 
ATOM   5258  C CD  . LYS B 1 234 ? 16.011  11.112  -57.503  1.00 31.54  ? 227  LYS B CD  1 
ATOM   5259  C CE  . LYS B 1 234 ? 17.403  10.578  -57.220  1.00 32.67  ? 227  LYS B CE  1 
ATOM   5260  N NZ  . LYS B 1 234 ? 17.967  9.866   -58.394  1.00 36.29  ? 227  LYS B NZ  1 
ATOM   5261  N N   . THR B 1 235 ? 11.129  10.899  -54.564  1.00 22.25  ? 228  THR B N   1 
ATOM   5262  C CA  . THR B 1 235 ? 9.796   10.237  -54.651  1.00 22.04  ? 228  THR B CA  1 
ATOM   5263  C C   . THR B 1 235 ? 8.777   10.964  -53.777  1.00 21.38  ? 228  THR B C   1 
ATOM   5264  O O   . THR B 1 235 ? 7.634   10.516  -53.735  1.00 22.43  ? 228  THR B O   1 
ATOM   5265  C CB  . THR B 1 235 ? 9.886   8.755   -54.270  1.00 21.78  ? 228  THR B CB  1 
ATOM   5266  O OG1 . THR B 1 235 ? 10.347  8.646   -52.921  1.00 22.17  ? 228  THR B OG1 1 
ATOM   5267  C CG2 . THR B 1 235 ? 10.808  7.978   -55.187  1.00 20.39  ? 228  THR B CG2 1 
ATOM   5268  N N   . GLY B 1 236 ? 9.177   12.046  -53.114  1.00 21.77  ? 229  GLY B N   1 
ATOM   5269  C CA  . GLY B 1 236 ? 8.284   12.843  -52.253  1.00 23.21  ? 229  GLY B CA  1 
ATOM   5270  C C   . GLY B 1 236 ? 8.039   12.212  -50.886  1.00 23.92  ? 229  GLY B C   1 
ATOM   5271  O O   . GLY B 1 236 ? 7.093   12.677  -50.229  1.00 22.29  ? 229  GLY B O   1 
ATOM   5272  N N   . ASP B 1 237 ? 8.877   11.246  -50.458  1.00 24.00  ? 230  ASP B N   1 
ATOM   5273  C CA  . ASP B 1 237 ? 8.783   10.516  -49.161  1.00 22.98  ? 230  ASP B CA  1 
ATOM   5274  C C   . ASP B 1 237 ? 9.962   10.939  -48.291  1.00 22.30  ? 230  ASP B C   1 
ATOM   5275  O O   . ASP B 1 237 ? 10.676  10.055  -47.756  1.00 20.72  ? 230  ASP B O   1 
ATOM   5276  C CB  . ASP B 1 237 ? 8.821   8.996   -49.352  1.00 24.26  ? 230  ASP B CB  1 
ATOM   5277  C CG  . ASP B 1 237 ? 7.815   8.439   -50.339  1.00 24.97  ? 230  ASP B CG  1 
ATOM   5278  O OD1 . ASP B 1 237 ? 6.606   8.375   -49.981  1.00 25.08  ? 230  ASP B OD1 1 
ATOM   5279  O OD2 . ASP B 1 237 ? 8.257   8.065   -51.447  1.00 24.15  ? 230  ASP B OD2 1 
ATOM   5280  N N   . ASP B 1 238 ? 10.134  12.252  -48.145  1.00 22.71  ? 231  ASP B N   1 
ATOM   5281  C CA  . ASP B 1 238 ? 11.313  12.891  -47.506  1.00 24.21  ? 231  ASP B CA  1 
ATOM   5282  C C   . ASP B 1 238 ? 11.507  12.352  -46.088  1.00 21.08  ? 231  ASP B C   1 
ATOM   5283  O O   . ASP B 1 238 ? 10.529  12.062  -45.394  1.00 20.04  ? 231  ASP B O   1 
ATOM   5284  C CB  . ASP B 1 238 ? 11.189  14.414  -47.499  1.00 27.75  ? 231  ASP B CB  1 
ATOM   5285  C CG  . ASP B 1 238 ? 10.991  15.005  -48.883  1.00 32.66  ? 231  ASP B CG  1 
ATOM   5286  O OD1 . ASP B 1 238 ? 9.840   14.923  -49.399  1.00 39.93  ? 231  ASP B OD1 1 
ATOM   5287  O OD2 . ASP B 1 238 ? 11.989  15.498  -49.463  1.00 32.68  ? 231  ASP B OD2 1 
ATOM   5288  N N   . VAL B 1 239 ? 12.763  12.256  -45.674  1.00 19.66  ? 232  VAL B N   1 
ATOM   5289  C CA  . VAL B 1 239 ? 13.157  11.592  -44.398  1.00 20.21  ? 232  VAL B CA  1 
ATOM   5290  C C   . VAL B 1 239 ? 13.020  12.611  -43.265  1.00 19.22  ? 232  VAL B C   1 
ATOM   5291  O O   . VAL B 1 239 ? 13.609  13.702  -43.378  1.00 20.69  ? 232  VAL B O   1 
ATOM   5292  C CB  . VAL B 1 239 ? 14.571  11.001  -44.522  1.00 19.03  ? 232  VAL B CB  1 
ATOM   5293  C CG1 . VAL B 1 239 ? 15.127  10.514  -43.202  1.00 18.83  ? 232  VAL B CG1 1 
ATOM   5294  C CG2 . VAL B 1 239 ? 14.574  9.882   -45.553  1.00 19.67  ? 232  VAL B CG2 1 
ATOM   5295  N N   . ALA B 1 240 ? 12.238  12.266  -42.244  1.00 18.74  ? 233  ALA B N   1 
ATOM   5296  C CA  . ALA B 1 240 ? 12.041  13.068  -41.020  1.00 18.50  ? 233  ALA B CA  1 
ATOM   5297  C C   . ALA B 1 240 ? 13.286  12.951  -40.145  1.00 18.81  ? 233  ALA B C   1 
ATOM   5298  O O   . ALA B 1 240 ? 13.763  13.984  -39.630  1.00 20.04  ? 233  ALA B O   1 
ATOM   5299  C CB  . ALA B 1 240 ? 10.804  12.610  -40.284  1.00 18.62  ? 233  ALA B CB  1 
ATOM   5300  N N   . ALA B 1 241 ? 13.793  11.731  -39.971  1.00 18.03  ? 234  ALA B N   1 
ATOM   5301  C CA  . ALA B 1 241 ? 14.897  11.462  -39.038  1.00 15.96  ? 234  ALA B CA  1 
ATOM   5302  C C   . ALA B 1 241 ? 15.664  10.222  -39.456  1.00 14.89  ? 234  ALA B C   1 
ATOM   5303  O O   . ALA B 1 241 ? 15.082  9.295   -40.029  1.00 12.91  ? 234  ALA B O   1 
ATOM   5304  C CB  . ALA B 1 241 ? 14.339  11.304  -37.646  1.00 16.92  ? 234  ALA B CB  1 
ATOM   5305  N N   . VAL B 1 242 ? 16.949  10.247  -39.133  1.00 15.59  ? 235  VAL B N   1 
ATOM   5306  C CA  . VAL B 1 242 ? 17.811  9.044   -39.053  1.00 15.83  ? 235  VAL B CA  1 
ATOM   5307  C C   . VAL B 1 242 ? 17.981  8.694   -37.573  1.00 16.72  ? 235  VAL B C   1 
ATOM   5308  O O   . VAL B 1 242 ? 18.314  9.593   -36.773  1.00 16.93  ? 235  VAL B O   1 
ATOM   5309  C CB  . VAL B 1 242 ? 19.162  9.295   -39.730  1.00 15.37  ? 235  VAL B CB  1 
ATOM   5310  C CG1 . VAL B 1 242 ? 20.042  8.069   -39.698  1.00 14.89  ? 235  VAL B CG1 1 
ATOM   5311  C CG2 . VAL B 1 242 ? 18.965  9.747   -41.160  1.00 16.34  ? 235  VAL B CG2 1 
ATOM   5312  N N   . ILE B 1 243 ? 17.781  7.425   -37.236  1.00 16.96  ? 236  ILE B N   1 
ATOM   5313  C CA  . ILE B 1 243 ? 18.078  6.896   -35.883  1.00 17.70  ? 236  ILE B CA  1 
ATOM   5314  C C   . ILE B 1 243 ? 19.133  5.811   -36.031  1.00 17.64  ? 236  ILE B C   1 
ATOM   5315  O O   . ILE B 1 243 ? 18.955  4.937   -36.896  1.00 15.99  ? 236  ILE B O   1 
ATOM   5316  C CB  . ILE B 1 243 ? 16.809  6.359   -35.184  1.00 18.36  ? 236  ILE B CB  1 
ATOM   5317  C CG1 . ILE B 1 243 ? 17.120  5.889   -33.758  1.00 18.40  ? 236  ILE B CG1 1 
ATOM   5318  C CG2 . ILE B 1 243 ? 16.156  5.257   -36.014  1.00 18.87  ? 236  ILE B CG2 1 
ATOM   5319  C CD1 . ILE B 1 243 ? 15.887  5.521   -32.964  1.00 19.13  ? 236  ILE B CD1 1 
ATOM   5320  N N   . LEU B 1 244 ? 20.147  5.836   -35.165  1.00 21.06  ? 237  LEU B N   1 
ATOM   5321  C CA  . LEU B 1 244 ? 21.197  4.785   -35.126  1.00 23.36  ? 237  LEU B CA  1 
ATOM   5322  C C   . LEU B 1 244 ? 21.843  4.742   -33.752  1.00 22.72  ? 237  LEU B C   1 
ATOM   5323  O O   . LEU B 1 244 ? 21.828  5.771   -33.039  1.00 24.17  ? 237  LEU B O   1 
ATOM   5324  C CB  . LEU B 1 244 ? 22.218  5.023   -36.251  1.00 25.46  ? 237  LEU B CB  1 
ATOM   5325  C CG  . LEU B 1 244 ? 23.116  6.262   -36.156  1.00 26.68  ? 237  LEU B CG  1 
ATOM   5326  C CD1 . LEU B 1 244 ? 24.095  6.260   -37.322  1.00 25.23  ? 237  LEU B CD1 1 
ATOM   5327  C CD2 . LEU B 1 244 ? 22.321  7.566   -36.177  1.00 27.81  ? 237  LEU B CD2 1 
ATOM   5328  N N   . GLU B 1 245 ? 22.353  3.569   -33.396  1.00 24.01  ? 238  GLU B N   1 
ATOM   5329  C CA  . GLU B 1 245 ? 23.297  3.408   -32.261  1.00 23.68  ? 238  GLU B CA  1 
ATOM   5330  C C   . GLU B 1 245 ? 24.671  3.826   -32.772  1.00 22.96  ? 238  GLU B C   1 
ATOM   5331  O O   . GLU B 1 245 ? 25.034  3.459   -33.878  1.00 23.90  ? 238  GLU B O   1 
ATOM   5332  C CB  . GLU B 1 245 ? 23.371  1.952   -31.794  1.00 24.57  ? 238  GLU B CB  1 
ATOM   5333  C CG  . GLU B 1 245 ? 22.052  1.299   -31.445  1.00 25.13  ? 238  GLU B CG  1 
ATOM   5334  C CD  . GLU B 1 245 ? 22.071  -0.228  -31.570  1.00 25.27  ? 238  GLU B CD  1 
ATOM   5335  O OE1 . GLU B 1 245 ? 22.519  -0.904  -30.602  1.00 26.46  ? 238  GLU B OE1 1 
ATOM   5336  O OE2 . GLU B 1 245 ? 21.664  -0.743  -32.644  1.00 22.52  ? 238  GLU B OE2 1 
ATOM   5337  N N   . PRO B 1 246 ? 25.483  4.573   -32.003  1.00 22.85  ? 239  PRO B N   1 
ATOM   5338  C CA  . PRO B 1 246 ? 26.848  4.895   -32.412  1.00 23.20  ? 239  PRO B CA  1 
ATOM   5339  C C   . PRO B 1 246 ? 27.701  3.640   -32.627  1.00 22.45  ? 239  PRO B C   1 
ATOM   5340  O O   . PRO B 1 246 ? 28.624  3.686   -33.410  1.00 22.62  ? 239  PRO B O   1 
ATOM   5341  C CB  . PRO B 1 246 ? 27.441  5.679   -31.224  1.00 23.67  ? 239  PRO B CB  1 
ATOM   5342  C CG  . PRO B 1 246 ? 26.237  6.137   -30.419  1.00 24.84  ? 239  PRO B CG  1 
ATOM   5343  C CD  . PRO B 1 246 ? 25.151  5.106   -30.674  1.00 25.16  ? 239  PRO B CD  1 
ATOM   5344  N N   . ILE B 1 247 ? 27.402  2.592   -31.859  1.00 22.72  ? 240  ILE B N   1 
ATOM   5345  C CA  . ILE B 1 247 ? 27.983  1.220   -31.937  1.00 22.70  ? 240  ILE B CA  1 
ATOM   5346  C C   . ILE B 1 247 ? 26.817  0.275   -31.680  1.00 23.25  ? 240  ILE B C   1 
ATOM   5347  O O   . ILE B 1 247 ? 26.093  0.509   -30.694  1.00 23.23  ? 240  ILE B O   1 
ATOM   5348  C CB  . ILE B 1 247 ? 29.116  1.017   -30.907  1.00 22.34  ? 240  ILE B CB  1 
ATOM   5349  C CG1 . ILE B 1 247 ? 30.257  2.006   -31.153  1.00 22.65  ? 240  ILE B CG1 1 
ATOM   5350  C CG2 . ILE B 1 247 ? 29.618  -0.429  -30.881  1.00 21.89  ? 240  ILE B CG2 1 
ATOM   5351  C CD1 . ILE B 1 247 ? 31.177  2.189   -29.974  1.00 23.60  ? 240  ILE B CD1 1 
ATOM   5352  N N   . GLN B 1 248 ? 26.630  -0.731  -32.522  1.00 23.12  ? 241  GLN B N   1 
ATOM   5353  C CA  . GLN B 1 248 ? 25.491  -1.653  -32.364  1.00 23.64  ? 241  GLN B CA  1 
ATOM   5354  C C   . GLN B 1 248 ? 25.865  -2.647  -31.276  1.00 23.53  ? 241  GLN B C   1 
ATOM   5355  O O   . GLN B 1 248 ? 26.894  -3.313  -31.424  1.00 23.81  ? 241  GLN B O   1 
ATOM   5356  C CB  . GLN B 1 248 ? 25.141  -2.299  -33.697  1.00 25.10  ? 241  GLN B CB  1 
ATOM   5357  C CG  . GLN B 1 248 ? 24.653  -1.273  -34.711  1.00 25.35  ? 241  GLN B CG  1 
ATOM   5358  C CD  . GLN B 1 248 ? 24.159  -1.903  -35.979  1.00 23.54  ? 241  GLN B CD  1 
ATOM   5359  O OE1 . GLN B 1 248 ? 23.385  -1.301  -36.705  1.00 24.79  ? 241  GLN B OE1 1 
ATOM   5360  N NE2 . GLN B 1 248 ? 24.589  -3.133  -36.218  1.00 22.77  ? 241  GLN B NE2 1 
ATOM   5361  N N   . GLY B 1 249 ? 25.096  -2.652  -30.192  1.00 25.13  ? 242  GLY B N   1 
ATOM   5362  C CA  . GLY B 1 249 ? 25.233  -3.625  -29.100  1.00 26.58  ? 242  GLY B CA  1 
ATOM   5363  C C   . GLY B 1 249 ? 24.682  -4.974  -29.524  1.00 30.21  ? 242  GLY B C   1 
ATOM   5364  O O   . GLY B 1 249 ? 25.477  -5.910  -29.688  1.00 25.81  ? 242  GLY B O   1 
ATOM   5365  N N   . GLU B 1 250 ? 23.362  -5.071  -29.723  1.00 34.88  ? 243  GLU B N   1 
ATOM   5366  C CA  . GLU B 1 250 ? 22.689  -6.376  -29.942  1.00 38.60  ? 243  GLU B CA  1 
ATOM   5367  C C   . GLU B 1 250 ? 23.158  -6.937  -31.288  1.00 35.92  ? 243  GLU B C   1 
ATOM   5368  O O   . GLU B 1 250 ? 23.165  -8.187  -31.440  1.00 34.37  ? 243  GLU B O   1 
ATOM   5369  C CB  . GLU B 1 250 ? 21.173  -6.223  -29.816  1.00 44.93  ? 243  GLU B CB  1 
ATOM   5370  C CG  . GLU B 1 250 ? 20.714  -5.643  -28.473  1.00 50.21  ? 243  GLU B CG  1 
ATOM   5371  C CD  . GLU B 1 250 ? 21.245  -6.260  -27.185  1.00 54.59  ? 243  GLU B CD  1 
ATOM   5372  O OE1 . GLU B 1 250 ? 21.450  -7.496  -27.158  1.00 61.29  ? 243  GLU B OE1 1 
ATOM   5373  O OE2 . GLU B 1 250 ? 21.459  -5.501  -26.195  1.00 57.13  ? 243  GLU B OE2 1 
ATOM   5374  N N   . GLY B 1 251 ? 23.581  -6.040  -32.192  1.00 36.74  ? 244  GLY B N   1 
ATOM   5375  C CA  . GLY B 1 251 ? 24.210  -6.366  -33.489  1.00 34.92  ? 244  GLY B CA  1 
ATOM   5376  C C   . GLY B 1 251 ? 25.487  -7.184  -33.330  1.00 34.83  ? 244  GLY B C   1 
ATOM   5377  O O   . GLY B 1 251 ? 25.894  -7.793  -34.332  1.00 41.85  ? 244  GLY B O   1 
ATOM   5378  N N   . GLY B 1 252 ? 26.114  -7.161  -32.140  1.00 33.96  ? 245  GLY B N   1 
ATOM   5379  C CA  . GLY B 1 252 ? 27.321  -7.941  -31.779  1.00 33.78  ? 245  GLY B CA  1 
ATOM   5380  C C   . GLY B 1 252 ? 28.560  -7.064  -31.604  1.00 34.57  ? 245  GLY B C   1 
ATOM   5381  O O   . GLY B 1 252 ? 29.672  -7.550  -31.913  1.00 38.51  ? 245  GLY B O   1 
ATOM   5382  N N   . VAL B 1 253 ? 28.397  -5.832  -31.102  1.00 32.77  ? 246  VAL B N   1 
ATOM   5383  C CA  . VAL B 1 253 ? 29.474  -4.802  -30.941  1.00 33.99  ? 246  VAL B CA  1 
ATOM   5384  C C   . VAL B 1 253 ? 30.065  -4.495  -32.311  1.00 30.65  ? 246  VAL B C   1 
ATOM   5385  O O   . VAL B 1 253 ? 31.189  -4.905  -32.617  1.00 27.30  ? 246  VAL B O   1 
ATOM   5386  C CB  . VAL B 1 253 ? 30.552  -5.218  -29.925  1.00 37.62  ? 246  VAL B CB  1 
ATOM   5387  C CG1 . VAL B 1 253 ? 31.586  -4.119  -29.731  1.00 37.19  ? 246  VAL B CG1 1 
ATOM   5388  C CG2 . VAL B 1 253 ? 29.902  -5.590  -28.597  1.00 41.18  ? 246  VAL B CG2 1 
ATOM   5389  N N   . ILE B 1 254 ? 29.258  -3.824  -33.117  1.00 29.41  ? 247  ILE B N   1 
ATOM   5390  C CA  . ILE B 1 254 ? 29.612  -3.465  -34.505  1.00 29.43  ? 247  ILE B CA  1 
ATOM   5391  C C   . ILE B 1 254 ? 30.063  -2.019  -34.458  1.00 27.04  ? 247  ILE B C   1 
ATOM   5392  O O   . ILE B 1 254 ? 29.242  -1.143  -34.183  1.00 27.08  ? 247  ILE B O   1 
ATOM   5393  C CB  . ILE B 1 254 ? 28.420  -3.667  -35.455  1.00 33.48  ? 247  ILE B CB  1 
ATOM   5394  C CG1 . ILE B 1 254 ? 27.825  -5.080  -35.367  1.00 34.17  ? 247  ILE B CG1 1 
ATOM   5395  C CG2 . ILE B 1 254 ? 28.843  -3.315  -36.870  1.00 34.33  ? 247  ILE B CG2 1 
ATOM   5396  C CD1 . ILE B 1 254 ? 28.848  -6.201  -35.469  1.00 35.13  ? 247  ILE B CD1 1 
ATOM   5397  N N   . LEU B 1 255 ? 31.343  -1.807  -34.676  1.00 27.49  ? 248  LEU B N   1 
ATOM   5398  C CA  . LEU B 1 255 ? 31.952  -0.460  -34.703  1.00 29.00  ? 248  LEU B CA  1 
ATOM   5399  C C   . LEU B 1 255 ? 31.855  0.070   -36.129  1.00 30.25  ? 248  LEU B C   1 
ATOM   5400  O O   . LEU B 1 255 ? 32.252  -0.594  -37.090  1.00 31.32  ? 248  LEU B O   1 
ATOM   5401  C CB  . LEU B 1 255 ? 33.407  -0.534  -34.223  1.00 28.83  ? 248  LEU B CB  1 
ATOM   5402  C CG  . LEU B 1 255 ? 33.599  -0.410  -32.716  1.00 27.97  ? 248  LEU B CG  1 
ATOM   5403  C CD1 . LEU B 1 255 ? 32.941  -1.577  -31.991  1.00 28.15  ? 248  LEU B CD1 1 
ATOM   5404  C CD2 . LEU B 1 255 ? 35.070  -0.330  -32.375  1.00 29.65  ? 248  LEU B CD2 1 
ATOM   5405  N N   . PRO B 1 256 ? 31.338  1.300   -36.297  1.00 30.32  ? 249  PRO B N   1 
ATOM   5406  C CA  . PRO B 1 256 ? 31.282  1.925   -37.617  1.00 30.14  ? 249  PRO B CA  1 
ATOM   5407  C C   . PRO B 1 256 ? 32.682  2.340   -38.054  1.00 29.99  ? 249  PRO B C   1 
ATOM   5408  O O   . PRO B 1 256 ? 33.573  2.449   -37.226  1.00 28.69  ? 249  PRO B O   1 
ATOM   5409  C CB  . PRO B 1 256 ? 30.409  3.154   -37.366  1.00 30.44  ? 249  PRO B CB  1 
ATOM   5410  C CG  . PRO B 1 256 ? 30.702  3.504   -35.930  1.00 31.96  ? 249  PRO B CG  1 
ATOM   5411  C CD  . PRO B 1 256 ? 30.881  2.182   -35.211  1.00 31.65  ? 249  PRO B CD  1 
ATOM   5412  N N   . PRO B 1 257 ? 32.931  2.635   -39.347  1.00 32.39  ? 250  PRO B N   1 
ATOM   5413  C CA  . PRO B 1 257 ? 34.221  3.173   -39.755  1.00 30.93  ? 250  PRO B CA  1 
ATOM   5414  C C   . PRO B 1 257 ? 34.368  4.528   -39.079  1.00 30.08  ? 250  PRO B C   1 
ATOM   5415  O O   . PRO B 1 257 ? 33.395  5.227   -38.814  1.00 26.93  ? 250  PRO B O   1 
ATOM   5416  C CB  . PRO B 1 257 ? 34.176  3.289   -41.283  1.00 29.18  ? 250  PRO B CB  1 
ATOM   5417  C CG  . PRO B 1 257 ? 32.895  2.554   -41.695  1.00 31.90  ? 250  PRO B CG  1 
ATOM   5418  C CD  . PRO B 1 257 ? 31.992  2.543   -40.476  1.00 32.00  ? 250  PRO B CD  1 
ATOM   5419  N N   . PRO B 1 258 ? 35.608  4.938   -38.769  1.00 31.66  ? 251  PRO B N   1 
ATOM   5420  C CA  . PRO B 1 258 ? 35.850  6.249   -38.180  1.00 31.85  ? 251  PRO B CA  1 
ATOM   5421  C C   . PRO B 1 258 ? 35.306  7.366   -39.087  1.00 30.76  ? 251  PRO B C   1 
ATOM   5422  O O   . PRO B 1 258 ? 35.363  7.222   -40.293  1.00 28.70  ? 251  PRO B O   1 
ATOM   5423  C CB  . PRO B 1 258 ? 37.387  6.293   -38.017  1.00 31.93  ? 251  PRO B CB  1 
ATOM   5424  C CG  . PRO B 1 258 ? 37.911  5.225   -38.954  1.00 32.61  ? 251  PRO B CG  1 
ATOM   5425  C CD  . PRO B 1 258 ? 36.836  4.165   -38.984  1.00 33.29  ? 251  PRO B CD  1 
ATOM   5426  N N   . GLY B 1 259 ? 34.749  8.421   -38.481  1.00 30.14  ? 252  GLY B N   1 
ATOM   5427  C CA  . GLY B 1 259 ? 34.151  9.579   -39.176  1.00 31.09  ? 252  GLY B CA  1 
ATOM   5428  C C   . GLY B 1 259 ? 32.709  9.346   -39.636  1.00 30.90  ? 252  GLY B C   1 
ATOM   5429  O O   . GLY B 1 259 ? 32.088  10.338  -40.061  1.00 36.01  ? 252  GLY B O   1 
ATOM   5430  N N   . TYR B 1 260 ? 32.195  8.103   -39.594  1.00 26.44  ? 253  TYR B N   1 
ATOM   5431  C CA  . TYR B 1 260 ? 30.822  7.710   -40.027  1.00 23.70  ? 253  TYR B CA  1 
ATOM   5432  C C   . TYR B 1 260 ? 29.752  8.591   -39.371  1.00 20.44  ? 253  TYR B C   1 
ATOM   5433  O O   . TYR B 1 260 ? 28.890  9.165   -40.025  1.00 17.63  ? 253  TYR B O   1 
ATOM   5434  C CB  . TYR B 1 260 ? 30.528  6.265   -39.623  1.00 23.61  ? 253  TYR B CB  1 
ATOM   5435  C CG  . TYR B 1 260 ? 29.122  5.807   -39.911  1.00 22.35  ? 253  TYR B CG  1 
ATOM   5436  C CD1 . TYR B 1 260 ? 28.641  5.756   -41.209  1.00 22.95  ? 253  TYR B CD1 1 
ATOM   5437  C CD2 . TYR B 1 260 ? 28.282  5.394   -38.896  1.00 22.32  ? 253  TYR B CD2 1 
ATOM   5438  C CE1 . TYR B 1 260 ? 27.353  5.322   -41.487  1.00 22.18  ? 253  TYR B CE1 1 
ATOM   5439  C CE2 . TYR B 1 260 ? 26.994  4.949   -39.150  1.00 21.82  ? 253  TYR B CE2 1 
ATOM   5440  C CZ  . TYR B 1 260 ? 26.529  4.920   -40.454  1.00 22.69  ? 253  TYR B CZ  1 
ATOM   5441  O OH  . TYR B 1 260 ? 25.277  4.472   -40.734  1.00 23.38  ? 253  TYR B OH  1 
ATOM   5442  N N   . LEU B 1 261 ? 29.802  8.659   -38.053  1.00 19.60  ? 254  LEU B N   1 
ATOM   5443  C CA  . LEU B 1 261 ? 28.836  9.432   -37.252  1.00 18.89  ? 254  LEU B CA  1 
ATOM   5444  C C   . LEU B 1 261 ? 28.864  10.903  -37.680  1.00 18.46  ? 254  LEU B C   1 
ATOM   5445  O O   . LEU B 1 261 ? 27.791  11.503  -37.850  1.00 17.66  ? 254  LEU B O   1 
ATOM   5446  C CB  . LEU B 1 261 ? 29.228  9.232   -35.794  1.00 19.82  ? 254  LEU B CB  1 
ATOM   5447  C CG  . LEU B 1 261 ? 28.120  8.840   -34.831  1.00 22.47  ? 254  LEU B CG  1 
ATOM   5448  C CD1 . LEU B 1 261 ? 27.189  7.755   -35.406  1.00 23.22  ? 254  LEU B CD1 1 
ATOM   5449  C CD2 . LEU B 1 261 ? 28.748  8.396   -33.534  1.00 22.15  ? 254  LEU B CD2 1 
ATOM   5450  N N   . THR B 1 262 ? 30.050  11.455  -37.883  1.00 19.12  ? 255  THR B N   1 
ATOM   5451  C CA  . THR B 1 262 ? 30.264  12.866  -38.276  1.00 19.66  ? 255  THR B CA  1 
ATOM   5452  C C   . THR B 1 262 ? 29.589  13.092  -39.617  1.00 20.72  ? 255  THR B C   1 
ATOM   5453  O O   . THR B 1 262 ? 28.960  14.156  -39.784  1.00 21.46  ? 255  THR B O   1 
ATOM   5454  C CB  . THR B 1 262 ? 31.766  13.183  -38.367  1.00 19.58  ? 255  THR B CB  1 
ATOM   5455  O OG1 . THR B 1 262 ? 32.271  13.135  -37.032  1.00 18.62  ? 255  THR B OG1 1 
ATOM   5456  C CG2 . THR B 1 262 ? 32.060  14.505  -39.046  1.00 18.49  ? 255  THR B CG2 1 
ATOM   5457  N N   . ALA B 1 263 ? 29.755  12.123  -40.531  1.00 22.20  ? 256  ALA B N   1 
ATOM   5458  C CA  . ALA B 1 263 ? 29.248  12.171  -41.918  1.00 21.38  ? 256  ALA B CA  1 
ATOM   5459  C C   . ALA B 1 263 ? 27.716  12.090  -41.890  1.00 21.31  ? 256  ALA B C   1 
ATOM   5460  O O   . ALA B 1 263 ? 27.075  12.874  -42.619  1.00 19.89  ? 256  ALA B O   1 
ATOM   5461  C CB  . ALA B 1 263 ? 29.854  11.053  -42.728  1.00 21.73  ? 256  ALA B CB  1 
ATOM   5462  N N   . VAL B 1 264 ? 27.159  11.197  -41.061  1.00 20.82  ? 257  VAL B N   1 
ATOM   5463  C CA  . VAL B 1 264 ? 25.688  11.035  -40.893  1.00 20.70  ? 257  VAL B CA  1 
ATOM   5464  C C   . VAL B 1 264 ? 25.112  12.379  -40.439  1.00 22.10  ? 257  VAL B C   1 
ATOM   5465  O O   . VAL B 1 264 ? 24.033  12.746  -40.947  1.00 24.94  ? 257  VAL B O   1 
ATOM   5466  C CB  . VAL B 1 264 ? 25.333  9.897   -39.914  1.00 20.47  ? 257  VAL B CB  1 
ATOM   5467  C CG1 . VAL B 1 264 ? 23.854  9.918   -39.542  1.00 21.33  ? 257  VAL B CG1 1 
ATOM   5468  C CG2 . VAL B 1 264 ? 25.726  8.524   -40.447  1.00 19.60  ? 257  VAL B CG2 1 
ATOM   5469  N N   . ARG B 1 265 ? 25.799  13.083  -39.535  1.00 23.58  ? 258  ARG B N   1 
ATOM   5470  C CA  . ARG B 1 265 ? 25.373  14.404  -39.002  1.00 24.00  ? 258  ARG B CA  1 
ATOM   5471  C C   . ARG B 1 265 ? 25.347  15.425  -40.141  1.00 24.21  ? 258  ARG B C   1 
ATOM   5472  O O   . ARG B 1 265 ? 24.346  16.134  -40.262  1.00 23.09  ? 258  ARG B O   1 
ATOM   5473  C CB  . ARG B 1 265 ? 26.282  14.855  -37.853  1.00 25.11  ? 258  ARG B CB  1 
ATOM   5474  C CG  . ARG B 1 265 ? 26.173  16.334  -37.485  1.00 26.00  ? 258  ARG B CG  1 
ATOM   5475  C CD  . ARG B 1 265 ? 24.973  16.740  -36.641  1.00 26.21  ? 258  ARG B CD  1 
ATOM   5476  N NE  . ARG B 1 265 ? 23.694  16.826  -37.353  1.00 26.79  ? 258  ARG B NE  1 
ATOM   5477  C CZ  . ARG B 1 265 ? 22.512  16.931  -36.772  1.00 25.46  ? 258  ARG B CZ  1 
ATOM   5478  N NH1 . ARG B 1 265 ? 22.423  16.962  -35.457  1.00 25.64  ? 258  ARG B NH1 1 
ATOM   5479  N NH2 . ARG B 1 265 ? 21.419  16.988  -37.509  1.00 25.03  ? 258  ARG B NH2 1 
ATOM   5480  N N   . LYS B 1 266 ? 26.409  15.523  -40.939  1.00 27.94  ? 259  LYS B N   1 
ATOM   5481  C CA  . LYS B 1 266 ? 26.433  16.473  -42.082  1.00 31.14  ? 259  LYS B CA  1 
ATOM   5482  C C   . LYS B 1 266 ? 25.345  16.095  -43.099  1.00 29.09  ? 259  LYS B C   1 
ATOM   5483  O O   . LYS B 1 266 ? 24.703  17.005  -43.661  1.00 27.69  ? 259  LYS B O   1 
ATOM   5484  C CB  . LYS B 1 266 ? 27.810  16.496  -42.732  1.00 37.01  ? 259  LYS B CB  1 
ATOM   5485  C CG  . LYS B 1 266 ? 28.081  17.725  -43.591  1.00 42.29  ? 259  LYS B CG  1 
ATOM   5486  C CD  . LYS B 1 266 ? 29.311  18.559  -43.162  1.00 46.67  ? 259  LYS B CD  1 
ATOM   5487  C CE  . LYS B 1 266 ? 30.382  18.710  -44.229  1.00 47.41  ? 259  LYS B CE  1 
ATOM   5488  N NZ  . LYS B 1 266 ? 29.849  18.843  -45.610  1.00 48.64  ? 259  LYS B NZ  1 
ATOM   5489  N N   . LEU B 1 267 ? 25.166  14.797  -43.338  1.00 27.63  ? 260  LEU B N   1 
ATOM   5490  C CA  . LEU B 1 267 ? 24.166  14.241  -44.288  1.00 28.29  ? 260  LEU B CA  1 
ATOM   5491  C C   . LEU B 1 267 ? 22.753  14.619  -43.818  1.00 28.09  ? 260  LEU B C   1 
ATOM   5492  O O   . LEU B 1 267 ? 21.990  15.152  -44.617  1.00 27.60  ? 260  LEU B O   1 
ATOM   5493  C CB  . LEU B 1 267 ? 24.363  12.725  -44.349  1.00 29.05  ? 260  LEU B CB  1 
ATOM   5494  C CG  . LEU B 1 267 ? 23.592  11.998  -45.439  1.00 29.09  ? 260  LEU B CG  1 
ATOM   5495  C CD1 . LEU B 1 267 ? 24.286  12.221  -46.783  1.00 29.45  ? 260  LEU B CD1 1 
ATOM   5496  C CD2 . LEU B 1 267 ? 23.461  10.514  -45.092  1.00 28.76  ? 260  LEU B CD2 1 
ATOM   5497  N N   . CYS B 1 268 ? 22.435  14.389  -42.543  1.00 26.84  ? 261  CYS B N   1 
ATOM   5498  C CA  . CYS B 1 268 ? 21.167  14.835  -41.909  1.00 25.84  ? 261  CYS B CA  1 
ATOM   5499  C C   . CYS B 1 268 ? 21.034  16.361  -42.039  1.00 25.56  ? 261  CYS B C   1 
ATOM   5500  O O   . CYS B 1 268 ? 19.951  16.822  -42.393  1.00 26.69  ? 261  CYS B O   1 
ATOM   5501  C CB  . CYS B 1 268 ? 21.098  14.405  -40.445  1.00 27.36  ? 261  CYS B CB  1 
ATOM   5502  S SG  . CYS B 1 268 ? 20.817  12.629  -40.194  1.00 25.81  ? 261  CYS B SG  1 
ATOM   5503  N N   . ASP B 1 269 ? 22.084  17.129  -41.761  1.00 27.17  ? 262  ASP B N   1 
ATOM   5504  C CA  . ASP B 1 269 ? 22.049  18.610  -41.874  1.00 30.32  ? 262  ASP B CA  1 
ATOM   5505  C C   . ASP B 1 269 ? 21.688  19.020  -43.306  1.00 32.69  ? 262  ASP B C   1 
ATOM   5506  O O   . ASP B 1 269 ? 20.940  19.994  -43.465  1.00 36.62  ? 262  ASP B O   1 
ATOM   5507  C CB  . ASP B 1 269 ? 23.395  19.233  -41.505  1.00 31.55  ? 262  ASP B CB  1 
ATOM   5508  C CG  . ASP B 1 269 ? 23.639  19.280  -40.017  1.00 35.33  ? 262  ASP B CG  1 
ATOM   5509  O OD1 . ASP B 1 269 ? 22.641  19.275  -39.276  1.00 38.61  ? 262  ASP B OD1 1 
ATOM   5510  O OD2 . ASP B 1 269 ? 24.814  19.337  -39.610  1.00 35.78  ? 262  ASP B OD2 1 
ATOM   5511  N N   . GLU B 1 270 ? 22.224  18.318  -44.304  1.00 32.24  ? 263  GLU B N   1 
ATOM   5512  C CA  . GLU B 1 270 ? 22.079  18.657  -45.745  1.00 34.06  ? 263  GLU B CA  1 
ATOM   5513  C C   . GLU B 1 270 ? 20.620  18.457  -46.171  1.00 32.28  ? 263  GLU B C   1 
ATOM   5514  O O   . GLU B 1 270 ? 20.102  19.342  -46.870  1.00 35.41  ? 263  GLU B O   1 
ATOM   5515  C CB  . GLU B 1 270 ? 23.054  17.817  -46.578  1.00 36.24  ? 263  GLU B CB  1 
ATOM   5516  C CG  . GLU B 1 270 ? 22.727  17.728  -48.067  1.00 41.57  ? 263  GLU B CG  1 
ATOM   5517  C CD  . GLU B 1 270 ? 23.779  17.040  -48.925  1.00 42.85  ? 263  GLU B CD  1 
ATOM   5518  O OE1 . GLU B 1 270 ? 24.959  16.979  -48.499  1.00 44.23  ? 263  GLU B OE1 1 
ATOM   5519  O OE2 . GLU B 1 270 ? 23.415  16.574  -50.011  1.00 43.39  ? 263  GLU B OE2 1 
ATOM   5520  N N   . PHE B 1 271 ? 20.005  17.331  -45.789  1.00 29.46  ? 264  PHE B N   1 
ATOM   5521  C CA  . PHE B 1 271 ? 18.642  16.913  -46.216  1.00 28.74  ? 264  PHE B CA  1 
ATOM   5522  C C   . PHE B 1 271 ? 17.559  17.486  -45.292  1.00 27.34  ? 264  PHE B C   1 
ATOM   5523  O O   . PHE B 1 271 ? 16.373  17.269  -45.598  1.00 24.43  ? 264  PHE B O   1 
ATOM   5524  C CB  . PHE B 1 271 ? 18.550  15.386  -46.292  1.00 28.12  ? 264  PHE B CB  1 
ATOM   5525  C CG  . PHE B 1 271 ? 19.161  14.843  -47.551  1.00 28.67  ? 264  PHE B CG  1 
ATOM   5526  C CD1 . PHE B 1 271 ? 18.451  14.818  -48.739  1.00 30.15  ? 264  PHE B CD1 1 
ATOM   5527  C CD2 . PHE B 1 271 ? 20.482  14.428  -47.559  1.00 30.89  ? 264  PHE B CD2 1 
ATOM   5528  C CE1 . PHE B 1 271 ? 19.038  14.358  -49.905  1.00 31.70  ? 264  PHE B CE1 1 
ATOM   5529  C CE2 . PHE B 1 271 ? 21.075  13.971  -48.727  1.00 32.85  ? 264  PHE B CE2 1 
ATOM   5530  C CZ  . PHE B 1 271 ? 20.348  13.927  -49.896  1.00 33.30  ? 264  PHE B CZ  1 
ATOM   5531  N N   . GLY B 1 272 ? 17.942  18.174  -44.210  1.00 26.24  ? 265  GLY B N   1 
ATOM   5532  C CA  . GLY B 1 272 ? 17.010  18.699  -43.188  1.00 25.54  ? 265  GLY B CA  1 
ATOM   5533  C C   . GLY B 1 272 ? 16.309  17.594  -42.398  1.00 24.49  ? 265  GLY B C   1 
ATOM   5534  O O   . GLY B 1 272 ? 15.168  17.819  -41.979  1.00 25.08  ? 265  GLY B O   1 
ATOM   5535  N N   . ALA B 1 273 ? 16.961  16.439  -42.204  1.00 23.56  ? 266  ALA B N   1 
ATOM   5536  C CA  . ALA B 1 273 ? 16.485  15.315  -41.356  1.00 22.85  ? 266  ALA B CA  1 
ATOM   5537  C C   . ALA B 1 273 ? 17.047  15.467  -39.934  1.00 21.38  ? 266  ALA B C   1 
ATOM   5538  O O   . ALA B 1 273 ? 18.188  15.974  -39.800  1.00 18.07  ? 266  ALA B O   1 
ATOM   5539  C CB  . ALA B 1 273 ? 16.899  13.988  -41.946  1.00 21.84  ? 266  ALA B CB  1 
ATOM   5540  N N   . LEU B 1 274 ? 16.277  15.050  -38.920  1.00 20.84  ? 267  LEU B N   1 
ATOM   5541  C CA  . LEU B 1 274 ? 16.758  15.071  -37.511  1.00 22.36  ? 267  LEU B CA  1 
ATOM   5542  C C   . LEU B 1 274 ? 17.619  13.838  -37.261  1.00 22.29  ? 267  LEU B C   1 
ATOM   5543  O O   . LEU B 1 274 ? 17.312  12.745  -37.771  1.00 24.63  ? 267  LEU B O   1 
ATOM   5544  C CB  . LEU B 1 274 ? 15.589  15.118  -36.530  1.00 21.79  ? 267  LEU B CB  1 
ATOM   5545  C CG  . LEU B 1 274 ? 14.697  16.352  -36.626  1.00 22.71  ? 267  LEU B CG  1 
ATOM   5546  C CD1 . LEU B 1 274 ? 13.575  16.256  -35.600  1.00 24.20  ? 267  LEU B CD1 1 
ATOM   5547  C CD2 . LEU B 1 274 ? 15.504  17.632  -36.451  1.00 22.07  ? 267  LEU B CD2 1 
ATOM   5548  N N   . MET B 1 275 ? 18.689  14.041  -36.511  1.00 23.06  ? 268  MET B N   1 
ATOM   5549  C CA  . MET B 1 275 ? 19.607  12.954  -36.114  1.00 22.92  ? 268  MET B CA  1 
ATOM   5550  C C   . MET B 1 275 ? 19.225  12.483  -34.703  1.00 20.31  ? 268  MET B C   1 
ATOM   5551  O O   . MET B 1 275 ? 19.308  13.275  -33.758  1.00 18.76  ? 268  MET B O   1 
ATOM   5552  C CB  . MET B 1 275 ? 21.059  13.424  -36.165  1.00 22.55  ? 268  MET B CB  1 
ATOM   5553  C CG  . MET B 1 275 ? 22.016  12.338  -35.789  1.00 24.28  ? 268  MET B CG  1 
ATOM   5554  S SD  . MET B 1 275 ? 23.715  12.773  -36.167  1.00 24.18  ? 268  MET B SD  1 
ATOM   5555  C CE  . MET B 1 275 ? 24.521  11.219  -35.780  1.00 25.04  ? 268  MET B CE  1 
ATOM   5556  N N   . ILE B 1 276 ? 18.816  11.223  -34.604  1.00 18.36  ? 269  ILE B N   1 
ATOM   5557  C CA  . ILE B 1 276 ? 18.524  10.551  -33.317  1.00 18.30  ? 269  ILE B CA  1 
ATOM   5558  C C   . ILE B 1 276 ? 19.655  9.573   -33.026  1.00 18.94  ? 269  ILE B C   1 
ATOM   5559  O O   . ILE B 1 276 ? 19.827  8.621   -33.803  1.00 19.07  ? 269  ILE B O   1 
ATOM   5560  C CB  . ILE B 1 276 ? 17.168  9.839   -33.355  1.00 17.00  ? 269  ILE B CB  1 
ATOM   5561  C CG1 . ILE B 1 276 ? 16.044  10.810  -33.701  1.00 16.70  ? 269  ILE B CG1 1 
ATOM   5562  C CG2 . ILE B 1 276 ? 16.905  9.129   -32.045  1.00 16.40  ? 269  ILE B CG2 1 
ATOM   5563  C CD1 . ILE B 1 276 ? 14.688  10.147  -33.824  1.00 16.98  ? 269  ILE B CD1 1 
ATOM   5564  N N   . LEU B 1 277 ? 20.352  9.782   -31.909  1.00 20.57  ? 270  LEU B N   1 
ATOM   5565  C CA  . LEU B 1 277 ? 21.367  8.834   -31.401  1.00 21.80  ? 270  LEU B CA  1 
ATOM   5566  C C   . LEU B 1 277 ? 20.789  8.051   -30.230  1.00 20.79  ? 270  LEU B C   1 
ATOM   5567  O O   . LEU B 1 277 ? 20.463  8.669   -29.217  1.00 21.26  ? 270  LEU B O   1 
ATOM   5568  C CB  . LEU B 1 277 ? 22.623  9.601   -30.986  1.00 24.24  ? 270  LEU B CB  1 
ATOM   5569  C CG  . LEU B 1 277 ? 23.711  9.622   -32.051  1.00 25.34  ? 270  LEU B CG  1 
ATOM   5570  C CD1 . LEU B 1 277 ? 25.007  10.143  -31.465  1.00 26.36  ? 270  LEU B CD1 1 
ATOM   5571  C CD2 . LEU B 1 277 ? 23.915  8.236   -32.663  1.00 25.58  ? 270  LEU B CD2 1 
ATOM   5572  N N   . ASP B 1 278 ? 20.726  6.732   -30.392  1.00 21.19  ? 271  ASP B N   1 
ATOM   5573  C CA  . ASP B 1 278 ? 20.297  5.754   -29.361  1.00 23.37  ? 271  ASP B CA  1 
ATOM   5574  C C   . ASP B 1 278 ? 21.524  5.343   -28.537  1.00 23.90  ? 271  ASP B C   1 
ATOM   5575  O O   . ASP B 1 278 ? 22.222  4.357   -28.928  1.00 29.18  ? 271  ASP B O   1 
ATOM   5576  C CB  . ASP B 1 278 ? 19.606  4.562   -30.033  1.00 24.18  ? 271  ASP B CB  1 
ATOM   5577  C CG  . ASP B 1 278 ? 19.130  3.496   -29.067  1.00 24.55  ? 271  ASP B CG  1 
ATOM   5578  O OD1 . ASP B 1 278 ? 19.503  3.580   -27.890  1.00 23.71  ? 271  ASP B OD1 1 
ATOM   5579  O OD2 . ASP B 1 278 ? 18.398  2.578   -29.511  1.00 25.48  ? 271  ASP B OD2 1 
ATOM   5580  N N   . GLU B 1 279 ? 21.801  6.072   -27.453  1.00 23.06  ? 272  GLU B N   1 
ATOM   5581  C CA  . GLU B 1 279 ? 22.936  5.785   -26.533  1.00 23.09  ? 272  GLU B CA  1 
ATOM   5582  C C   . GLU B 1 279 ? 22.423  5.078   -25.285  1.00 22.41  ? 272  GLU B C   1 
ATOM   5583  O O   . GLU B 1 279 ? 23.078  5.144   -24.244  1.00 23.65  ? 272  GLU B O   1 
ATOM   5584  C CB  . GLU B 1 279 ? 23.670  7.072   -26.184  1.00 23.60  ? 272  GLU B CB  1 
ATOM   5585  C CG  . GLU B 1 279 ? 24.505  7.547   -27.353  1.00 24.89  ? 272  GLU B CG  1 
ATOM   5586  C CD  . GLU B 1 279 ? 25.969  7.779   -27.037  1.00 26.37  ? 272  GLU B CD  1 
ATOM   5587  O OE1 . GLU B 1 279 ? 26.527  7.099   -26.108  1.00 26.09  ? 272  GLU B OE1 1 
ATOM   5588  O OE2 . GLU B 1 279 ? 26.550  8.647   -27.724  1.00 27.84  ? 272  GLU B OE2 1 
ATOM   5589  N N   . VAL B 1 280 ? 21.272  4.425   -25.393  1.00 20.90  ? 273  VAL B N   1 
ATOM   5590  C CA  . VAL B 1 280 ? 20.727  3.561   -24.324  1.00 20.48  ? 273  VAL B CA  1 
ATOM   5591  C C   . VAL B 1 280 ? 21.837  2.627   -23.840  1.00 21.05  ? 273  VAL B C   1 
ATOM   5592  O O   . VAL B 1 280 ? 21.963  2.460   -22.614  1.00 20.32  ? 273  VAL B O   1 
ATOM   5593  C CB  . VAL B 1 280 ? 19.493  2.791   -24.812  1.00 19.19  ? 273  VAL B CB  1 
ATOM   5594  C CG1 . VAL B 1 280 ? 19.148  1.647   -23.870  1.00 18.96  ? 273  VAL B CG1 1 
ATOM   5595  C CG2 . VAL B 1 280 ? 18.316  3.735   -24.977  1.00 18.91  ? 273  VAL B CG2 1 
ATOM   5596  N N   . GLN B 1 281 ? 22.594  2.026   -24.751  1.00 23.75  ? 274  GLN B N   1 
ATOM   5597  C CA  . GLN B 1 281 ? 23.566  0.981   -24.356  1.00 27.39  ? 274  GLN B CA  1 
ATOM   5598  C C   . GLN B 1 281 ? 25.014  1.479   -24.371  1.00 23.78  ? 274  GLN B C   1 
ATOM   5599  O O   . GLN B 1 281 ? 25.809  0.911   -23.600  1.00 23.65  ? 274  GLN B O   1 
ATOM   5600  C CB  . GLN B 1 281 ? 23.430  -0.268  -25.201  1.00 32.63  ? 274  GLN B CB  1 
ATOM   5601  C CG  . GLN B 1 281 ? 24.168  -1.423  -24.549  1.00 38.48  ? 274  GLN B CG  1 
ATOM   5602  C CD  . GLN B 1 281 ? 23.827  -2.749  -25.172  1.00 47.16  ? 274  GLN B CD  1 
ATOM   5603  O OE1 . GLN B 1 281 ? 24.548  -3.727  -24.992  1.00 55.16  ? 274  GLN B OE1 1 
ATOM   5604  N NE2 . GLN B 1 281 ? 22.732  -2.789  -25.922  1.00 48.36  ? 274  GLN B NE2 1 
ATOM   5605  N N   . THR B 1 282 ? 25.322  2.543   -25.104  1.00 21.89  ? 275  THR B N   1 
ATOM   5606  C CA  . THR B 1 282 ? 26.697  3.115   -25.182  1.00 22.67  ? 275  THR B CA  1 
ATOM   5607  C C   . THR B 1 282 ? 26.874  4.305   -24.233  1.00 23.40  ? 275  THR B C   1 
ATOM   5608  O O   . THR B 1 282 ? 27.965  4.849   -24.190  1.00 27.34  ? 275  THR B O   1 
ATOM   5609  C CB  . THR B 1 282 ? 27.006  3.552   -26.612  1.00 21.60  ? 275  THR B CB  1 
ATOM   5610  O OG1 . THR B 1 282 ? 26.078  4.584   -26.952  1.00 21.47  ? 275  THR B OG1 1 
ATOM   5611  C CG2 . THR B 1 282 ? 26.897  2.399   -27.582  1.00 21.80  ? 275  THR B CG2 1 
ATOM   5612  N N   . GLY B 1 283 ? 25.849  4.692   -23.491  1.00 24.79  ? 276  GLY B N   1 
ATOM   5613  C CA  . GLY B 1 283 ? 25.875  5.907   -22.658  1.00 25.71  ? 276  GLY B CA  1 
ATOM   5614  C C   . GLY B 1 283 ? 26.377  5.645   -21.244  1.00 26.65  ? 276  GLY B C   1 
ATOM   5615  O O   . GLY B 1 283 ? 26.639  4.456   -20.861  1.00 26.45  ? 276  GLY B O   1 
ATOM   5616  N N   . MET B 1 284 ? 26.527  6.728   -20.479  1.00 24.13  ? 277  MET B N   1 
ATOM   5617  C CA  . MET B 1 284 ? 27.000  6.694   -19.078  1.00 23.97  ? 277  MET B CA  1 
ATOM   5618  C C   . MET B 1 284 ? 28.384  6.020   -18.996  1.00 23.86  ? 277  MET B C   1 
ATOM   5619  O O   . MET B 1 284 ? 28.569  5.159   -18.106  1.00 25.21  ? 277  MET B O   1 
ATOM   5620  C CB  . MET B 1 284 ? 25.968  5.968   -18.210  1.00 25.27  ? 277  MET B CB  1 
ATOM   5621  C CG  . MET B 1 284 ? 24.530  6.481   -18.393  1.00 25.09  ? 277  MET B CG  1 
ATOM   5622  S SD  . MET B 1 284 ? 24.369  8.278   -18.729  1.00 24.27  ? 277  MET B SD  1 
ATOM   5623  C CE  . MET B 1 284 ? 24.937  9.002   -17.192  1.00 26.15  ? 277  MET B CE  1 
ATOM   5624  N N   . GLY B 1 285 ? 29.314  6.396   -19.887  1.00 21.31  ? 278  GLY B N   1 
ATOM   5625  C CA  . GLY B 1 285 ? 30.750  6.127   -19.739  1.00 21.17  ? 278  GLY B CA  1 
ATOM   5626  C C   . GLY B 1 285 ? 31.199  4.800   -20.339  1.00 21.46  ? 278  GLY B C   1 
ATOM   5627  O O   . GLY B 1 285 ? 32.438  4.560   -20.346  1.00 19.55  ? 278  GLY B O   1 
ATOM   5628  N N   . ARG B 1 286 ? 30.283  3.947   -20.816  1.00 22.07  ? 279  ARG B N   1 
ATOM   5629  C CA  . ARG B 1 286 ? 30.634  2.528   -21.137  1.00 23.56  ? 279  ARG B CA  1 
ATOM   5630  C C   . ARG B 1 286 ? 31.726  2.395   -22.231  1.00 21.84  ? 279  ARG B C   1 
ATOM   5631  O O   . ARG B 1 286 ? 32.489  1.402   -22.184  1.00 19.87  ? 279  ARG B O   1 
ATOM   5632  C CB  . ARG B 1 286 ? 29.404  1.702   -21.520  1.00 24.15  ? 279  ARG B CB  1 
ATOM   5633  C CG  . ARG B 1 286 ? 29.809  0.314   -21.994  1.00 24.60  ? 279  ARG B CG  1 
ATOM   5634  C CD  . ARG B 1 286 ? 28.791  -0.748  -21.705  1.00 26.12  ? 279  ARG B CD  1 
ATOM   5635  N NE  . ARG B 1 286 ? 28.506  -0.894  -20.287  1.00 25.24  ? 279  ARG B NE  1 
ATOM   5636  C CZ  . ARG B 1 286 ? 29.160  -1.686  -19.448  1.00 25.36  ? 279  ARG B CZ  1 
ATOM   5637  N NH1 . ARG B 1 286 ? 30.207  -2.391  -19.860  1.00 25.06  ? 279  ARG B NH1 1 
ATOM   5638  N NH2 . ARG B 1 286 ? 28.762  -1.746  -18.182  1.00 25.92  ? 279  ARG B NH2 1 
ATOM   5639  N N   . THR B 1 287 ? 31.822  3.317   -23.186  1.00 21.24  ? 280  THR B N   1 
ATOM   5640  C CA  . THR B 1 287 ? 32.761  3.187   -24.339  1.00 23.90  ? 280  THR B CA  1 
ATOM   5641  C C   . THR B 1 287 ? 34.062  3.937   -24.077  1.00 23.75  ? 280  THR B C   1 
ATOM   5642  O O   . THR B 1 287 ? 34.903  3.949   -24.975  1.00 23.80  ? 280  THR B O   1 
ATOM   5643  C CB  . THR B 1 287 ? 32.153  3.726   -25.641  1.00 24.07  ? 280  THR B CB  1 
ATOM   5644  O OG1 . THR B 1 287 ? 31.937  5.139   -25.522  1.00 24.67  ? 280  THR B OG1 1 
ATOM   5645  C CG2 . THR B 1 287 ? 30.859  3.026   -25.981  1.00 24.32  ? 280  THR B CG2 1 
ATOM   5646  N N   . GLY B 1 288 ? 34.207  4.555   -22.907  1.00 23.97  ? 281  GLY B N   1 
ATOM   5647  C CA  . GLY B 1 288 ? 35.413  5.321   -22.564  1.00 24.84  ? 281  GLY B CA  1 
ATOM   5648  C C   . GLY B 1 288 ? 35.139  6.809   -22.542  1.00 25.34  ? 281  GLY B C   1 
ATOM   5649  O O   . GLY B 1 288 ? 36.016  7.557   -22.117  1.00 29.10  ? 281  GLY B O   1 
ATOM   5650  N N   . LYS B 1 289 ? 33.961  7.235   -22.966  1.00 27.86  ? 282  LYS B N   1 
ATOM   5651  C CA  . LYS B 1 289 ? 33.472  8.618   -22.728  1.00 30.23  ? 282  LYS B CA  1 
ATOM   5652  C C   . LYS B 1 289 ? 32.067  8.534   -22.140  1.00 27.89  ? 282  LYS B C   1 
ATOM   5653  O O   . LYS B 1 289 ? 31.472  7.446   -22.204  1.00 27.97  ? 282  LYS B O   1 
ATOM   5654  C CB  . LYS B 1 289 ? 33.444  9.432   -24.024  1.00 36.51  ? 282  LYS B CB  1 
ATOM   5655  C CG  . LYS B 1 289 ? 34.758  9.488   -24.794  1.00 40.69  ? 282  LYS B CG  1 
ATOM   5656  C CD  . LYS B 1 289 ? 35.598  10.697  -24.466  1.00 45.42  ? 282  LYS B CD  1 
ATOM   5657  C CE  . LYS B 1 289 ? 36.688  10.917  -25.490  1.00 50.70  ? 282  LYS B CE  1 
ATOM   5658  N NZ  . LYS B 1 289 ? 37.377  12.192  -25.213  1.00 52.71  ? 282  LYS B NZ  1 
ATOM   5659  N N   . MET B 1 290 ? 31.562  9.640   -21.601  1.00 26.08  ? 283  MET B N   1 
ATOM   5660  C CA  . MET B 1 290 ? 30.214  9.698   -20.986  1.00 26.57  ? 283  MET B CA  1 
ATOM   5661  C C   . MET B 1 290 ? 29.193  9.257   -22.048  1.00 26.04  ? 283  MET B C   1 
ATOM   5662  O O   . MET B 1 290 ? 28.313  8.452   -21.720  1.00 27.38  ? 283  MET B O   1 
ATOM   5663  C CB  . MET B 1 290 ? 29.894  11.107  -20.468  1.00 26.21  ? 283  MET B CB  1 
ATOM   5664  C CG  . MET B 1 290 ? 28.591  11.197  -19.683  1.00 25.12  ? 283  MET B CG  1 
ATOM   5665  S SD  . MET B 1 290 ? 28.567  9.994   -18.324  1.00 24.39  ? 283  MET B SD  1 
ATOM   5666  C CE  . MET B 1 290 ? 29.656  10.778  -17.138  1.00 25.47  ? 283  MET B CE  1 
ATOM   5667  N N   . PHE B 1 291 ? 29.350  9.718   -23.288  1.00 24.63  ? 284  PHE B N   1 
ATOM   5668  C CA  . PHE B 1 291 ? 28.553  9.274   -24.459  1.00 24.87  ? 284  PHE B CA  1 
ATOM   5669  C C   . PHE B 1 291 ? 29.489  8.944   -25.627  1.00 22.59  ? 284  PHE B C   1 
ATOM   5670  O O   . PHE B 1 291 ? 30.478  9.649   -25.833  1.00 25.11  ? 284  PHE B O   1 
ATOM   5671  C CB  . PHE B 1 291 ? 27.555  10.360  -24.858  1.00 25.82  ? 284  PHE B CB  1 
ATOM   5672  C CG  . PHE B 1 291 ? 26.839  11.006  -23.703  1.00 24.39  ? 284  PHE B CG  1 
ATOM   5673  C CD1 . PHE B 1 291 ? 25.940  10.281  -22.943  1.00 23.61  ? 284  PHE B CD1 1 
ATOM   5674  C CD2 . PHE B 1 291 ? 27.056  12.342  -23.395  1.00 24.83  ? 284  PHE B CD2 1 
ATOM   5675  C CE1 . PHE B 1 291 ? 25.274  10.881  -21.887  1.00 23.90  ? 284  PHE B CE1 1 
ATOM   5676  C CE2 . PHE B 1 291 ? 26.374  12.949  -22.351  1.00 25.03  ? 284  PHE B CE2 1 
ATOM   5677  C CZ  . PHE B 1 291 ? 25.487  12.214  -21.600  1.00 24.18  ? 284  PHE B CZ  1 
ATOM   5678  N N   . ALA B 1 292 ? 29.183  7.896   -26.376  1.00 22.07  ? 285  ALA B N   1 
ATOM   5679  C CA  . ALA B 1 292 ? 29.973  7.490   -27.558  1.00 23.69  ? 285  ALA B CA  1 
ATOM   5680  C C   . ALA B 1 292 ? 29.988  8.605   -28.616  1.00 24.45  ? 285  ALA B C   1 
ATOM   5681  O O   . ALA B 1 292 ? 30.935  8.610   -29.392  1.00 25.31  ? 285  ALA B O   1 
ATOM   5682  C CB  . ALA B 1 292 ? 29.461  6.196   -28.121  1.00 22.16  ? 285  ALA B CB  1 
ATOM   5683  N N   . CYS B 1 293 ? 29.025  9.535   -28.629  1.00 25.58  ? 286  CYS B N   1 
ATOM   5684  C CA  . CYS B 1 293 ? 28.992  10.666  -29.600  1.00 27.69  ? 286  CYS B CA  1 
ATOM   5685  C C   . CYS B 1 293 ? 30.121  11.658  -29.297  1.00 28.85  ? 286  CYS B C   1 
ATOM   5686  O O   . CYS B 1 293 ? 30.434  12.475  -30.168  1.00 28.39  ? 286  CYS B O   1 
ATOM   5687  C CB  . CYS B 1 293 ? 27.636  11.360  -29.647  1.00 27.55  ? 286  CYS B CB  1 
ATOM   5688  S SG  . CYS B 1 293 ? 27.167  12.292  -28.162  1.00 34.77  ? 286  CYS B SG  1 
ATOM   5689  N N   . GLU B 1 294 ? 30.755  11.561  -28.131  1.00 32.69  ? 287  GLU B N   1 
ATOM   5690  C CA  . GLU B 1 294 ? 31.859  12.473  -27.730  1.00 34.35  ? 287  GLU B CA  1 
ATOM   5691  C C   . GLU B 1 294 ? 33.179  12.064  -28.398  1.00 32.16  ? 287  GLU B C   1 
ATOM   5692  O O   . GLU B 1 294 ? 34.017  12.962  -28.563  1.00 29.89  ? 287  GLU B O   1 
ATOM   5693  C CB  . GLU B 1 294 ? 31.992  12.516  -26.208  1.00 39.70  ? 287  GLU B CB  1 
ATOM   5694  C CG  . GLU B 1 294 ? 30.797  13.174  -25.541  1.00 42.62  ? 287  GLU B CG  1 
ATOM   5695  C CD  . GLU B 1 294 ? 30.854  13.250  -24.026  1.00 44.92  ? 287  GLU B CD  1 
ATOM   5696  O OE1 . GLU B 1 294 ? 31.582  12.439  -23.397  1.00 46.02  ? 287  GLU B OE1 1 
ATOM   5697  O OE2 . GLU B 1 294 ? 30.143  14.118  -23.475  1.00 53.19  ? 287  GLU B OE2 1 
ATOM   5698  N N   . HIS B 1 295 ? 33.358  10.791  -28.783  1.00 30.01  ? 288  HIS B N   1 
ATOM   5699  C CA  . HIS B 1 295 ? 34.562  10.307  -29.512  1.00 29.92  ? 288  HIS B CA  1 
ATOM   5700  C C   . HIS B 1 295 ? 34.806  11.182  -30.746  1.00 32.09  ? 288  HIS B C   1 
ATOM   5701  O O   . HIS B 1 295 ? 35.974  11.562  -30.973  1.00 34.17  ? 288  HIS B O   1 
ATOM   5702  C CB  . HIS B 1 295 ? 34.440  8.833   -29.918  1.00 30.46  ? 288  HIS B CB  1 
ATOM   5703  C CG  . HIS B 1 295 ? 34.468  7.893   -28.767  1.00 32.00  ? 288  HIS B CG  1 
ATOM   5704  N ND1 . HIS B 1 295 ? 35.584  7.756   -27.962  1.00 35.78  ? 288  HIS B ND1 1 
ATOM   5705  C CD2 . HIS B 1 295 ? 33.527  7.066   -28.268  1.00 33.91  ? 288  HIS B CD2 1 
ATOM   5706  C CE1 . HIS B 1 295 ? 35.340  6.873   -27.019  1.00 37.26  ? 288  HIS B CE1 1 
ATOM   5707  N NE2 . HIS B 1 295 ? 34.081  6.434   -27.181  1.00 37.81  ? 288  HIS B NE2 1 
ATOM   5708  N N   . GLU B 1 296 ? 33.747  11.517  -31.496  1.00 30.82  ? 289  GLU B N   1 
ATOM   5709  C CA  . GLU B 1 296 ? 33.860  12.307  -32.744  1.00 31.40  ? 289  GLU B CA  1 
ATOM   5710  C C   . GLU B 1 296 ? 33.325  13.731  -32.540  1.00 30.79  ? 289  GLU B C   1 
ATOM   5711  O O   . GLU B 1 296 ? 33.332  14.496  -33.510  1.00 32.51  ? 289  GLU B O   1 
ATOM   5712  C CB  . GLU B 1 296 ? 33.097  11.596  -33.858  1.00 34.46  ? 289  GLU B CB  1 
ATOM   5713  C CG  . GLU B 1 296 ? 33.819  10.403  -34.460  1.00 35.71  ? 289  GLU B CG  1 
ATOM   5714  C CD  . GLU B 1 296 ? 33.153  9.843   -35.717  1.00 38.05  ? 289  GLU B CD  1 
ATOM   5715  O OE1 . GLU B 1 296 ? 32.402  10.579  -36.411  1.00 32.83  ? 289  GLU B OE1 1 
ATOM   5716  O OE2 . GLU B 1 296 ? 33.393  8.668   -36.022  1.00 46.73  ? 289  GLU B OE2 1 
ATOM   5717  N N   . ASN B 1 297 ? 32.918  14.097  -31.331  1.00 31.67  ? 290  ASN B N   1 
ATOM   5718  C CA  . ASN B 1 297 ? 32.281  15.407  -31.037  1.00 39.25  ? 290  ASN B CA  1 
ATOM   5719  C C   . ASN B 1 297 ? 31.084  15.614  -31.985  1.00 39.37  ? 290  ASN B C   1 
ATOM   5720  O O   . ASN B 1 297 ? 30.993  16.680  -32.663  1.00 39.81  ? 290  ASN B O   1 
ATOM   5721  C CB  . ASN B 1 297 ? 33.289  16.557  -31.112  1.00 45.34  ? 290  ASN B CB  1 
ATOM   5722  C CG  . ASN B 1 297 ? 32.826  17.789  -30.359  1.00 56.21  ? 290  ASN B CG  1 
ATOM   5723  O OD1 . ASN B 1 297 ? 31.945  17.714  -29.492  1.00 58.26  ? 290  ASN B OD1 1 
ATOM   5724  N ND2 . ASN B 1 297 ? 33.414  18.930  -30.689  1.00 61.76  ? 290  ASN B ND2 1 
ATOM   5725  N N   . VAL B 1 298 ? 30.202  14.616  -32.051  1.00 34.13  ? 291  VAL B N   1 
ATOM   5726  C CA  . VAL B 1 298 ? 28.925  14.660  -32.827  1.00 31.16  ? 291  VAL B CA  1 
ATOM   5727  C C   . VAL B 1 298 ? 27.788  15.078  -31.886  1.00 31.01  ? 291  VAL B C   1 
ATOM   5728  O O   . VAL B 1 298 ? 27.617  14.437  -30.836  1.00 29.17  ? 291  VAL B O   1 
ATOM   5729  C CB  . VAL B 1 298 ? 28.636  13.306  -33.496  1.00 30.22  ? 291  VAL B CB  1 
ATOM   5730  C CG1 . VAL B 1 298 ? 27.225  13.241  -34.037  1.00 30.91  ? 291  VAL B CG1 1 
ATOM   5731  C CG2 . VAL B 1 298 ? 29.638  13.012  -34.597  1.00 32.98  ? 291  VAL B CG2 1 
ATOM   5732  N N   . GLN B 1 299 ? 27.059  16.132  -32.236  1.00 30.71  ? 292  GLN B N   1 
ATOM   5733  C CA  . GLN B 1 299 ? 25.833  16.564  -31.528  1.00 34.25  ? 292  GLN B CA  1 
ATOM   5734  C C   . GLN B 1 299 ? 24.606  16.102  -32.315  1.00 31.16  ? 292  GLN B C   1 
ATOM   5735  O O   . GLN B 1 299 ? 24.293  16.675  -33.356  1.00 31.42  ? 292  GLN B O   1 
ATOM   5736  C CB  . GLN B 1 299 ? 25.868  18.081  -31.329  1.00 39.86  ? 292  GLN B CB  1 
ATOM   5737  C CG  . GLN B 1 299 ? 24.844  18.570  -30.308  1.00 44.36  ? 292  GLN B CG  1 
ATOM   5738  C CD  . GLN B 1 299 ? 24.044  19.758  -30.786  1.00 49.18  ? 292  GLN B CD  1 
ATOM   5739  O OE1 . GLN B 1 299 ? 24.537  20.887  -30.801  1.00 56.78  ? 292  GLN B OE1 1 
ATOM   5740  N NE2 . GLN B 1 299 ? 22.802  19.510  -31.188  1.00 50.07  ? 292  GLN B NE2 1 
ATOM   5741  N N   . PRO B 1 300 ? 23.854  15.076  -31.850  1.00 29.29  ? 293  PRO B N   1 
ATOM   5742  C CA  . PRO B 1 300 ? 22.579  14.714  -32.470  1.00 27.84  ? 293  PRO B CA  1 
ATOM   5743  C C   . PRO B 1 300 ? 21.525  15.753  -32.076  1.00 27.06  ? 293  PRO B C   1 
ATOM   5744  O O   . PRO B 1 300 ? 21.779  16.554  -31.197  1.00 27.31  ? 293  PRO B O   1 
ATOM   5745  C CB  . PRO B 1 300 ? 22.273  13.338  -31.875  1.00 26.32  ? 293  PRO B CB  1 
ATOM   5746  C CG  . PRO B 1 300 ? 22.834  13.452  -30.490  1.00 26.63  ? 293  PRO B CG  1 
ATOM   5747  C CD  . PRO B 1 300 ? 24.132  14.237  -30.677  1.00 27.69  ? 293  PRO B CD  1 
ATOM   5748  N N   . ASP B 1 301 ? 20.383  15.733  -32.759  1.00 27.29  ? 294  ASP B N   1 
ATOM   5749  C CA  . ASP B 1 301 ? 19.217  16.602  -32.441  1.00 25.88  ? 294  ASP B CA  1 
ATOM   5750  C C   . ASP B 1 301 ? 18.540  16.052  -31.196  1.00 24.28  ? 294  ASP B C   1 
ATOM   5751  O O   . ASP B 1 301 ? 18.051  16.852  -30.381  1.00 27.85  ? 294  ASP B O   1 
ATOM   5752  C CB  . ASP B 1 301 ? 18.259  16.670  -33.621  1.00 25.80  ? 294  ASP B CB  1 
ATOM   5753  C CG  . ASP B 1 301 ? 18.918  17.347  -34.805  1.00 27.48  ? 294  ASP B CG  1 
ATOM   5754  O OD1 . ASP B 1 301 ? 19.293  18.537  -34.653  1.00 29.00  ? 294  ASP B OD1 1 
ATOM   5755  O OD2 . ASP B 1 301 ? 19.156  16.658  -35.819  1.00 28.76  ? 294  ASP B OD2 1 
ATOM   5756  N N   . ILE B 1 302 ? 18.518  14.725  -31.090  1.00 21.65  ? 295  ILE B N   1 
ATOM   5757  C CA  . ILE B 1 302 ? 17.815  13.969  -30.019  1.00 20.47  ? 295  ILE B CA  1 
ATOM   5758  C C   . ILE B 1 302 ? 18.727  12.825  -29.580  1.00 20.11  ? 295  ILE B C   1 
ATOM   5759  O O   . ILE B 1 302 ? 19.232  12.093  -30.461  1.00 17.84  ? 295  ILE B O   1 
ATOM   5760  C CB  . ILE B 1 302 ? 16.458  13.434  -30.493  1.00 19.78  ? 295  ILE B CB  1 
ATOM   5761  C CG1 . ILE B 1 302 ? 15.580  14.519  -31.121  1.00 19.84  ? 295  ILE B CG1 1 
ATOM   5762  C CG2 . ILE B 1 302 ? 15.754  12.735  -29.346  1.00 20.42  ? 295  ILE B CG2 1 
ATOM   5763  C CD1 . ILE B 1 302 ? 14.367  13.979  -31.863  1.00 18.67  ? 295  ILE B CD1 1 
ATOM   5764  N N   . LEU B 1 303 ? 18.912  12.707  -28.264  1.00 19.83  ? 296  LEU B N   1 
ATOM   5765  C CA  . LEU B 1 303 ? 19.756  11.687  -27.602  1.00 20.52  ? 296  LEU B CA  1 
ATOM   5766  C C   . LEU B 1 303 ? 18.884  10.834  -26.671  1.00 23.00  ? 296  LEU B C   1 
ATOM   5767  O O   . LEU B 1 303 ? 18.086  11.403  -25.864  1.00 23.65  ? 296  LEU B O   1 
ATOM   5768  C CB  . LEU B 1 303 ? 20.847  12.418  -26.828  1.00 20.44  ? 296  LEU B CB  1 
ATOM   5769  C CG  . LEU B 1 303 ? 21.797  11.522  -26.035  1.00 20.71  ? 296  LEU B CG  1 
ATOM   5770  C CD1 . LEU B 1 303 ? 22.541  10.535  -26.930  1.00 20.34  ? 296  LEU B CD1 1 
ATOM   5771  C CD2 . LEU B 1 303 ? 22.787  12.365  -25.242  1.00 19.88  ? 296  LEU B CD2 1 
ATOM   5772  N N   . CYS B 1 304 ? 19.019  9.511   -26.783  1.00 22.29  ? 297  CYS B N   1 
ATOM   5773  C CA  . CYS B 1 304 ? 18.262  8.532   -25.970  1.00 21.42  ? 297  CYS B CA  1 
ATOM   5774  C C   . CYS B 1 304 ? 19.197  7.859   -24.965  1.00 20.79  ? 297  CYS B C   1 
ATOM   5775  O O   . CYS B 1 304 ? 20.289  7.385   -25.362  1.00 17.33  ? 297  CYS B O   1 
ATOM   5776  C CB  . CYS B 1 304 ? 17.604  7.503   -26.864  1.00 22.21  ? 297  CYS B CB  1 
ATOM   5777  S SG  . CYS B 1 304 ? 16.419  8.260   -28.008  1.00 23.78  ? 297  CYS B SG  1 
ATOM   5778  N N   . LEU B 1 305 ? 18.752  7.813   -23.708  1.00 20.99  ? 298  LEU B N   1 
ATOM   5779  C CA  . LEU B 1 305 ? 19.493  7.199   -22.583  1.00 20.73  ? 298  LEU B CA  1 
ATOM   5780  C C   . LEU B 1 305 ? 18.553  6.312   -21.778  1.00 19.93  ? 298  LEU B C   1 
ATOM   5781  O O   . LEU B 1 305 ? 17.385  6.689   -21.602  1.00 21.52  ? 298  LEU B O   1 
ATOM   5782  C CB  . LEU B 1 305 ? 20.038  8.307   -21.687  1.00 20.79  ? 298  LEU B CB  1 
ATOM   5783  C CG  . LEU B 1 305 ? 21.002  9.291   -22.331  1.00 20.20  ? 298  LEU B CG  1 
ATOM   5784  C CD1 . LEU B 1 305 ? 21.433  10.326  -21.296  1.00 20.44  ? 298  LEU B CD1 1 
ATOM   5785  C CD2 . LEU B 1 305 ? 22.209  8.568   -22.910  1.00 21.06  ? 298  LEU B CD2 1 
ATOM   5786  N N   . ALA B 1 306 ? 19.094  5.212   -21.265  1.00 19.43  ? 299  ALA B N   1 
ATOM   5787  C CA  . ALA B 1 306 ? 18.484  4.358   -20.229  1.00 19.51  ? 299  ALA B CA  1 
ATOM   5788  C C   . ALA B 1 306 ? 19.582  3.468   -19.645  1.00 18.81  ? 299  ALA B C   1 
ATOM   5789  O O   . ALA B 1 306 ? 20.685  3.969   -19.513  1.00 22.15  ? 299  ALA B O   1 
ATOM   5790  C CB  . ALA B 1 306 ? 17.327  3.579   -20.825  1.00 19.73  ? 299  ALA B CB  1 
ATOM   5791  N N   . LYS B 1 307 ? 19.284  2.205   -19.341  1.00 19.40  ? 300  LYS B N   1 
ATOM   5792  C CA  . LYS B 1 307 ? 20.155  1.211   -18.655  1.00 19.75  ? 300  LYS B CA  1 
ATOM   5793  C C   . LYS B 1 307 ? 20.929  1.878   -17.502  1.00 19.00  ? 300  LYS B C   1 
ATOM   5794  O O   . LYS B 1 307 ? 20.333  2.130   -16.460  1.00 18.81  ? 300  LYS B O   1 
ATOM   5795  C CB  . LYS B 1 307 ? 21.033  0.538   -19.708  1.00 21.22  ? 300  LYS B CB  1 
ATOM   5796  C CG  . LYS B 1 307 ? 20.245  -0.134  -20.807  1.00 24.37  ? 300  LYS B CG  1 
ATOM   5797  C CD  . LYS B 1 307 ? 20.979  -1.152  -21.639  1.00 25.65  ? 300  LYS B CD  1 
ATOM   5798  C CE  . LYS B 1 307 ? 20.034  -2.293  -21.945  1.00 29.38  ? 300  LYS B CE  1 
ATOM   5799  N NZ  . LYS B 1 307 ? 20.534  -3.238  -22.962  1.00 35.46  ? 300  LYS B NZ  1 
ATOM   5800  N N   . ALA B 1 308 ? 22.203  2.201   -17.714  1.00 18.20  ? 301  ALA B N   1 
ATOM   5801  C CA  . ALA B 1 308 ? 23.148  2.626   -16.676  1.00 18.98  ? 301  ALA B CA  1 
ATOM   5802  C C   . ALA B 1 308 ? 22.704  3.950   -16.051  1.00 19.17  ? 301  ALA B C   1 
ATOM   5803  O O   . ALA B 1 308 ? 23.148  4.210   -14.925  1.00 18.82  ? 301  ALA B O   1 
ATOM   5804  C CB  . ALA B 1 308 ? 24.551  2.710   -17.251  1.00 19.23  ? 301  ALA B CB  1 
ATOM   5805  N N   . LEU B 1 309 ? 21.886  4.762   -16.724  1.00 18.30  ? 302  LEU B N   1 
ATOM   5806  C CA  . LEU B 1 309 ? 21.468  6.073   -16.155  1.00 19.32  ? 302  LEU B CA  1 
ATOM   5807  C C   . LEU B 1 309 ? 20.817  5.897   -14.771  1.00 19.16  ? 302  LEU B C   1 
ATOM   5808  O O   . LEU B 1 309 ? 20.835  6.864   -13.989  1.00 19.41  ? 302  LEU B O   1 
ATOM   5809  C CB  . LEU B 1 309 ? 20.509  6.759   -17.125  1.00 20.49  ? 302  LEU B CB  1 
ATOM   5810  C CG  . LEU B 1 309 ? 20.054  8.157   -16.714  1.00 20.80  ? 302  LEU B CG  1 
ATOM   5811  C CD1 . LEU B 1 309 ? 21.229  9.093   -16.593  1.00 21.24  ? 302  LEU B CD1 1 
ATOM   5812  C CD2 . LEU B 1 309 ? 19.055  8.705   -17.707  1.00 22.81  ? 302  LEU B CD2 1 
ATOM   5813  N N   . GLY B 1 310 ? 20.237  4.730   -14.472  1.00 19.21  ? 303  GLY B N   1 
ATOM   5814  C CA  . GLY B 1 310 ? 19.545  4.462   -13.194  1.00 19.15  ? 303  GLY B CA  1 
ATOM   5815  C C   . GLY B 1 310 ? 20.474  3.929   -12.119  1.00 19.65  ? 303  GLY B C   1 
ATOM   5816  O O   . GLY B 1 310 ? 20.014  3.701   -10.995  1.00 19.71  ? 303  GLY B O   1 
ATOM   5817  N N   . GLY B 1 311 ? 21.744  3.706   -12.450  1.00 20.03  ? 304  GLY B N   1 
ATOM   5818  C CA  . GLY B 1 311 ? 22.782  3.367   -11.454  1.00 19.90  ? 304  GLY B CA  1 
ATOM   5819  C C   . GLY B 1 311 ? 22.742  1.905   -11.053  1.00 19.95  ? 304  GLY B C   1 
ATOM   5820  O O   . GLY B 1 311 ? 23.400  1.574   -10.072  1.00 19.59  ? 304  GLY B O   1 
ATOM   5821  N N   . GLY B 1 312 ? 22.022  1.050   -11.800  1.00 20.62  ? 305  GLY B N   1 
ATOM   5822  C CA  . GLY B 1 312 ? 21.814  -0.372  -11.447  1.00 19.59  ? 305  GLY B CA  1 
ATOM   5823  C C   . GLY B 1 312 ? 20.950  -0.509  -10.205  1.00 18.01  ? 305  GLY B C   1 
ATOM   5824  O O   . GLY B 1 312 ? 20.990  -1.557  -9.540   1.00 15.01  ? 305  GLY B O   1 
ATOM   5825  N N   . VAL B 1 313 ? 20.163  0.523   -9.926   1.00 19.66  ? 306  VAL B N   1 
ATOM   5826  C CA  . VAL B 1 313 ? 19.199  0.528   -8.789   1.00 22.31  ? 306  VAL B CA  1 
ATOM   5827  C C   . VAL B 1 313 ? 17.783  0.775   -9.323   1.00 20.90  ? 306  VAL B C   1 
ATOM   5828  O O   . VAL B 1 313 ? 16.911  -0.045  -9.006   1.00 21.62  ? 306  VAL B O   1 
ATOM   5829  C CB  . VAL B 1 313 ? 19.632  1.548   -7.718   1.00 22.86  ? 306  VAL B CB  1 
ATOM   5830  C CG1 . VAL B 1 313 ? 18.709  1.528   -6.520   1.00 23.81  ? 306  VAL B CG1 1 
ATOM   5831  C CG2 . VAL B 1 313 ? 21.068  1.309   -7.289   1.00 22.85  ? 306  VAL B CG2 1 
ATOM   5832  N N   . MET B 1 314 ? 17.577  1.827   -10.125  1.00 20.92  ? 307  MET B N   1 
ATOM   5833  C CA  . MET B 1 314 ? 16.235  2.269   -10.615  1.00 21.67  ? 307  MET B CA  1 
ATOM   5834  C C   . MET B 1 314 ? 16.112  2.109   -12.132  1.00 22.29  ? 307  MET B C   1 
ATOM   5835  O O   . MET B 1 314 ? 17.072  2.338   -12.885  1.00 19.67  ? 307  MET B O   1 
ATOM   5836  C CB  . MET B 1 314 ? 15.966  3.738   -10.267  1.00 22.28  ? 307  MET B CB  1 
ATOM   5837  C CG  . MET B 1 314 ? 15.600  3.964   -8.812   1.00 22.56  ? 307  MET B CG  1 
ATOM   5838  S SD  . MET B 1 314 ? 14.162  3.009   -8.311   1.00 23.86  ? 307  MET B SD  1 
ATOM   5839  C CE  . MET B 1 314 ? 12.848  3.950   -9.091   1.00 22.45  ? 307  MET B CE  1 
ATOM   5840  N N   . PRO B 1 315 ? 14.905  1.726   -12.621  1.00 22.13  ? 308  PRO B N   1 
ATOM   5841  C CA  . PRO B 1 315 ? 14.568  1.839   -14.032  1.00 22.93  ? 308  PRO B CA  1 
ATOM   5842  C C   . PRO B 1 315 ? 14.338  3.316   -14.343  1.00 22.73  ? 308  PRO B C   1 
ATOM   5843  O O   . PRO B 1 315 ? 13.582  3.950   -13.607  1.00 24.02  ? 308  PRO B O   1 
ATOM   5844  C CB  . PRO B 1 315 ? 13.274  1.040   -14.174  1.00 23.36  ? 308  PRO B CB  1 
ATOM   5845  C CG  . PRO B 1 315 ? 12.637  1.179   -12.838  1.00 22.92  ? 308  PRO B CG  1 
ATOM   5846  C CD  . PRO B 1 315 ? 13.794  1.153   -11.856  1.00 23.34  ? 308  PRO B CD  1 
ATOM   5847  N N   . ILE B 1 316 ? 15.035  3.825   -15.357  1.00 21.77  ? 309  ILE B N   1 
ATOM   5848  C CA  . ILE B 1 316 ? 14.821  5.198   -15.889  1.00 22.96  ? 309  ILE B CA  1 
ATOM   5849  C C   . ILE B 1 316 ? 15.221  5.220   -17.367  1.00 22.06  ? 309  ILE B C   1 
ATOM   5850  O O   . ILE B 1 316 ? 16.142  4.467   -17.749  1.00 23.09  ? 309  ILE B O   1 
ATOM   5851  C CB  . ILE B 1 316 ? 15.598  6.241   -15.064  1.00 23.25  ? 309  ILE B CB  1 
ATOM   5852  C CG1 . ILE B 1 316 ? 15.305  7.676   -15.519  1.00 23.84  ? 309  ILE B CG1 1 
ATOM   5853  C CG2 . ILE B 1 316 ? 17.080  5.941   -15.105  1.00 24.76  ? 309  ILE B CG2 1 
ATOM   5854  C CD1 . ILE B 1 316 ? 15.905  8.733   -14.614  1.00 23.79  ? 309  ILE B CD1 1 
ATOM   5855  N N   . GLY B 1 317 ? 14.550  6.064   -18.142  1.00 21.24  ? 310  GLY B N   1 
ATOM   5856  C CA  . GLY B 1 317 ? 14.993  6.486   -19.481  1.00 23.27  ? 310  GLY B CA  1 
ATOM   5857  C C   . GLY B 1 317 ? 14.977  7.995   -19.570  1.00 23.78  ? 310  GLY B C   1 
ATOM   5858  O O   . GLY B 1 317 ? 14.243  8.636   -18.796  1.00 25.61  ? 310  GLY B O   1 
ATOM   5859  N N   . ALA B 1 318 ? 15.784  8.559   -20.452  1.00 23.83  ? 311  ALA B N   1 
ATOM   5860  C CA  . ALA B 1 318 ? 15.787  10.009  -20.728  1.00 25.40  ? 311  ALA B CA  1 
ATOM   5861  C C   . ALA B 1 318 ? 15.887  10.224  -22.236  1.00 26.72  ? 311  ALA B C   1 
ATOM   5862  O O   . ALA B 1 318 ? 16.691  9.537   -22.900  1.00 30.48  ? 311  ALA B O   1 
ATOM   5863  C CB  . ALA B 1 318 ? 16.926  10.676  -20.012  1.00 26.14  ? 311  ALA B CB  1 
ATOM   5864  N N   . THR B 1 319 ? 15.094  11.154  -22.740  1.00 25.17  ? 312  THR B N   1 
ATOM   5865  C CA  . THR B 1 319 ? 15.191  11.668  -24.108  1.00 25.67  ? 312  THR B CA  1 
ATOM   5866  C C   . THR B 1 319 ? 15.561  13.139  -23.985  1.00 26.60  ? 312  THR B C   1 
ATOM   5867  O O   . THR B 1 319 ? 14.769  13.884  -23.401  1.00 28.52  ? 312  THR B O   1 
ATOM   5868  C CB  . THR B 1 319 ? 13.875  11.412  -24.847  1.00 26.36  ? 312  THR B CB  1 
ATOM   5869  O OG1 . THR B 1 319 ? 13.553  10.029  -24.676  1.00 26.53  ? 312  THR B OG1 1 
ATOM   5870  C CG2 . THR B 1 319 ? 13.948  11.770  -26.315  1.00 25.19  ? 312  THR B CG2 1 
ATOM   5871  N N   . ILE B 1 320 ? 16.725  13.522  -24.496  1.00 27.61  ? 313  ILE B N   1 
ATOM   5872  C CA  . ILE B 1 320 ? 17.205  14.934  -24.468  1.00 29.75  ? 313  ILE B CA  1 
ATOM   5873  C C   . ILE B 1 320 ? 17.258  15.422  -25.910  1.00 27.51  ? 313  ILE B C   1 
ATOM   5874  O O   . ILE B 1 320 ? 17.634  14.632  -26.776  1.00 26.55  ? 313  ILE B O   1 
ATOM   5875  C CB  . ILE B 1 320 ? 18.581  15.044  -23.786  1.00 33.53  ? 313  ILE B CB  1 
ATOM   5876  C CG1 . ILE B 1 320 ? 18.612  14.233  -22.487  1.00 37.52  ? 313  ILE B CG1 1 
ATOM   5877  C CG2 . ILE B 1 320 ? 18.970  16.502  -23.554  1.00 32.77  ? 313  ILE B CG2 1 
ATOM   5878  C CD1 . ILE B 1 320 ? 19.728  13.214  -22.425  1.00 38.24  ? 313  ILE B CD1 1 
ATOM   5879  N N   . ALA B 1 321 ? 16.908  16.684  -26.131  1.00 26.44  ? 314  ALA B N   1 
ATOM   5880  C CA  . ALA B 1 321 ? 16.803  17.289  -27.471  1.00 27.25  ? 314  ALA B CA  1 
ATOM   5881  C C   . ALA B 1 321 ? 17.092  18.782  -27.391  1.00 26.47  ? 314  ALA B C   1 
ATOM   5882  O O   . ALA B 1 321 ? 17.081  19.337  -26.289  1.00 25.57  ? 314  ALA B O   1 
ATOM   5883  C CB  . ALA B 1 321 ? 15.427  17.045  -28.018  1.00 28.48  ? 314  ALA B CB  1 
ATOM   5884  N N   . THR B 1 322 ? 17.332  19.385  -28.550  1.00 25.54  ? 315  THR B N   1 
ATOM   5885  C CA  . THR B 1 322 ? 17.492  20.846  -28.737  1.00 27.39  ? 315  THR B CA  1 
ATOM   5886  C C   . THR B 1 322 ? 16.193  21.545  -28.328  1.00 27.86  ? 315  THR B C   1 
ATOM   5887  O O   . THR B 1 322 ? 15.139  20.904  -28.392  1.00 27.38  ? 315  THR B O   1 
ATOM   5888  C CB  . THR B 1 322 ? 17.845  21.162  -30.194  1.00 27.83  ? 315  THR B CB  1 
ATOM   5889  O OG1 . THR B 1 322 ? 16.842  20.547  -30.999  1.00 29.62  ? 315  THR B OG1 1 
ATOM   5890  C CG2 . THR B 1 322 ? 19.197  20.636  -30.610  1.00 29.54  ? 315  THR B CG2 1 
ATOM   5891  N N   . GLU B 1 323 ? 16.275  22.821  -27.955  1.00 30.41  ? 316  GLU B N   1 
ATOM   5892  C CA  . GLU B 1 323 ? 15.095  23.694  -27.738  1.00 33.46  ? 316  GLU B CA  1 
ATOM   5893  C C   . GLU B 1 323 ? 14.282  23.724  -29.026  1.00 32.33  ? 316  GLU B C   1 
ATOM   5894  O O   . GLU B 1 323 ? 13.049  23.695  -28.935  1.00 31.50  ? 316  GLU B O   1 
ATOM   5895  C CB  . GLU B 1 323 ? 15.514  25.103  -27.306  1.00 36.06  ? 316  GLU B CB  1 
ATOM   5896  C CG  . GLU B 1 323 ? 14.339  26.057  -27.119  1.00 37.44  ? 316  GLU B CG  1 
ATOM   5897  C CD  . GLU B 1 323 ? 14.515  27.125  -26.067  1.00 42.19  ? 316  GLU B CD  1 
ATOM   5898  O OE1 . GLU B 1 323 ? 15.593  27.155  -25.428  1.00 44.50  ? 316  GLU B OE1 1 
ATOM   5899  O OE2 . GLU B 1 323 ? 13.555  27.902  -25.872  1.00 48.71  ? 316  GLU B OE2 1 
ATOM   5900  N N   . GLU B 1 324 ? 14.972  23.765  -30.173  1.00 35.37  ? 317  GLU B N   1 
ATOM   5901  C CA  . GLU B 1 324 ? 14.374  23.865  -31.531  1.00 38.00  ? 317  GLU B CA  1 
ATOM   5902  C C   . GLU B 1 324 ? 13.359  22.724  -31.708  1.00 35.20  ? 317  GLU B C   1 
ATOM   5903  O O   . GLU B 1 324 ? 12.226  23.021  -32.098  1.00 34.26  ? 317  GLU B O   1 
ATOM   5904  C CB  . GLU B 1 324 ? 15.491  23.877  -32.585  1.00 42.94  ? 317  GLU B CB  1 
ATOM   5905  C CG  . GLU B 1 324 ? 15.018  24.019  -34.027  1.00 47.76  ? 317  GLU B CG  1 
ATOM   5906  C CD  . GLU B 1 324 ? 14.102  25.194  -34.337  1.00 51.98  ? 317  GLU B CD  1 
ATOM   5907  O OE1 . GLU B 1 324 ? 14.197  26.235  -33.635  1.00 59.17  ? 317  GLU B OE1 1 
ATOM   5908  O OE2 . GLU B 1 324 ? 13.293  25.062  -35.280  1.00 50.13  ? 317  GLU B OE2 1 
ATOM   5909  N N   . VAL B 1 325 ? 13.745  21.487  -31.378  1.00 32.74  ? 318  VAL B N   1 
ATOM   5910  C CA  . VAL B 1 325 ? 12.923  20.248  -31.545  1.00 29.40  ? 318  VAL B CA  1 
ATOM   5911  C C   . VAL B 1 325 ? 11.927  20.101  -30.393  1.00 27.86  ? 318  VAL B C   1 
ATOM   5912  O O   . VAL B 1 325 ? 10.754  19.819  -30.652  1.00 27.12  ? 318  VAL B O   1 
ATOM   5913  C CB  . VAL B 1 325 ? 13.829  19.009  -31.638  1.00 29.30  ? 318  VAL B CB  1 
ATOM   5914  C CG1 . VAL B 1 325 ? 13.031  17.722  -31.568  1.00 28.79  ? 318  VAL B CG1 1 
ATOM   5915  C CG2 . VAL B 1 325 ? 14.667  19.039  -32.897  1.00 30.36  ? 318  VAL B CG2 1 
ATOM   5916  N N   . PHE B 1 326 ? 12.394  20.218  -29.155  1.00 28.14  ? 319  PHE B N   1 
ATOM   5917  C CA  . PHE B 1 326 ? 11.588  19.916  -27.946  1.00 28.78  ? 319  PHE B CA  1 
ATOM   5918  C C   . PHE B 1 326 ? 10.432  20.920  -27.840  1.00 28.90  ? 319  PHE B C   1 
ATOM   5919  O O   . PHE B 1 326 ? 9.372   20.535  -27.345  1.00 26.10  ? 319  PHE B O   1 
ATOM   5920  C CB  . PHE B 1 326 ? 12.483  19.918  -26.709  1.00 29.90  ? 319  PHE B CB  1 
ATOM   5921  C CG  . PHE B 1 326 ? 12.026  19.016  -25.590  1.00 30.91  ? 319  PHE B CG  1 
ATOM   5922  C CD1 . PHE B 1 326 ? 11.065  19.445  -24.688  1.00 30.42  ? 319  PHE B CD1 1 
ATOM   5923  C CD2 . PHE B 1 326 ? 12.614  17.766  -25.395  1.00 31.23  ? 319  PHE B CD2 1 
ATOM   5924  C CE1 . PHE B 1 326 ? 10.674  18.623  -23.639  1.00 30.94  ? 319  PHE B CE1 1 
ATOM   5925  C CE2 . PHE B 1 326 ? 12.214  16.942  -24.352  1.00 30.07  ? 319  PHE B CE2 1 
ATOM   5926  C CZ  . PHE B 1 326 ? 11.234  17.371  -23.482  1.00 30.52  ? 319  PHE B CZ  1 
ATOM   5927  N N   . SER B 1 327 ? 10.617  22.147  -28.344  1.00 31.52  ? 320  SER B N   1 
ATOM   5928  C CA  . SER B 1 327 ? 9.638   23.264  -28.241  1.00 33.08  ? 320  SER B CA  1 
ATOM   5929  C C   . SER B 1 327 ? 8.282   22.862  -28.841  1.00 35.36  ? 320  SER B C   1 
ATOM   5930  O O   . SER B 1 327 ? 7.292   23.617  -28.640  1.00 35.96  ? 320  SER B O   1 
ATOM   5931  C CB  . SER B 1 327 ? 10.154  24.537  -28.868  1.00 34.51  ? 320  SER B CB  1 
ATOM   5932  O OG  . SER B 1 327 ? 10.364  24.371  -30.262  1.00 35.01  ? 320  SER B OG  1 
ATOM   5933  N N   . VAL B 1 328 ? 8.220   21.717  -29.528  1.00 34.79  ? 321  VAL B N   1 
ATOM   5934  C CA  . VAL B 1 328 ? 6.942   21.150  -30.054  1.00 36.04  ? 321  VAL B CA  1 
ATOM   5935  C C   . VAL B 1 328 ? 6.007   20.794  -28.890  1.00 34.26  ? 321  VAL B C   1 
ATOM   5936  O O   . VAL B 1 328 ? 4.781   20.697  -29.169  1.00 33.60  ? 321  VAL B O   1 
ATOM   5937  C CB  . VAL B 1 328 ? 7.157   19.933  -30.979  1.00 38.22  ? 321  VAL B CB  1 
ATOM   5938  C CG1 . VAL B 1 328 ? 7.915   20.318  -32.244  1.00 37.63  ? 321  VAL B CG1 1 
ATOM   5939  C CG2 . VAL B 1 328 ? 7.825   18.756  -30.267  1.00 37.78  ? 321  VAL B CG2 1 
ATOM   5940  N N   . LEU B 1 329 ? 6.539   20.620  -27.665  1.00 32.48  ? 322  LEU B N   1 
ATOM   5941  C CA  . LEU B 1 329 ? 5.769   20.175  -26.468  1.00 31.45  ? 322  LEU B CA  1 
ATOM   5942  C C   . LEU B 1 329 ? 5.385   21.359  -25.571  1.00 31.55  ? 322  LEU B C   1 
ATOM   5943  O O   . LEU B 1 329 ? 4.708   21.115  -24.552  1.00 29.32  ? 322  LEU B O   1 
ATOM   5944  C CB  . LEU B 1 329 ? 6.604   19.171  -25.667  1.00 31.33  ? 322  LEU B CB  1 
ATOM   5945  C CG  . LEU B 1 329 ? 7.051   17.907  -26.397  1.00 31.34  ? 322  LEU B CG  1 
ATOM   5946  C CD1 . LEU B 1 329 ? 7.702   16.938  -25.423  1.00 31.33  ? 322  LEU B CD1 1 
ATOM   5947  C CD2 . LEU B 1 329 ? 5.897   17.237  -27.116  1.00 31.87  ? 322  LEU B CD2 1 
ATOM   5948  N N   . PHE B 1 330 ? 5.751   22.590  -25.940  1.00 33.81  ? 323  PHE B N   1 
ATOM   5949  C CA  . PHE B 1 330 ? 5.623   23.800  -25.084  1.00 37.06  ? 323  PHE B CA  1 
ATOM   5950  C C   . PHE B 1 330 ? 4.184   24.329  -25.048  1.00 41.52  ? 323  PHE B C   1 
ATOM   5951  O O   . PHE B 1 330 ? 3.775   24.801  -23.971  1.00 43.37  ? 323  PHE B O   1 
ATOM   5952  C CB  . PHE B 1 330 ? 6.575   24.902  -25.559  1.00 37.05  ? 323  PHE B CB  1 
ATOM   5953  C CG  . PHE B 1 330 ? 8.038   24.651  -25.286  1.00 37.15  ? 323  PHE B CG  1 
ATOM   5954  C CD1 . PHE B 1 330 ? 8.479   23.460  -24.722  1.00 36.08  ? 323  PHE B CD1 1 
ATOM   5955  C CD2 . PHE B 1 330 ? 8.987   25.602  -25.634  1.00 38.40  ? 323  PHE B CD2 1 
ATOM   5956  C CE1 . PHE B 1 330 ? 9.828   23.241  -24.489  1.00 37.11  ? 323  PHE B CE1 1 
ATOM   5957  C CE2 . PHE B 1 330 ? 10.335  25.382  -25.402  1.00 37.64  ? 323  PHE B CE2 1 
ATOM   5958  C CZ  . PHE B 1 330 ? 10.751  24.201  -24.831  1.00 37.54  ? 323  PHE B CZ  1 
ATOM   5959  N N   . ASP B 1 331 ? 3.466   24.315  -26.176  1.00 44.19  ? 324  ASP B N   1 
ATOM   5960  C CA  . ASP B 1 331 ? 2.101   24.898  -26.287  1.00 49.87  ? 324  ASP B CA  1 
ATOM   5961  C C   . ASP B 1 331 ? 1.101   23.969  -25.610  1.00 48.75  ? 324  ASP B C   1 
ATOM   5962  O O   . ASP B 1 331 ? 0.155   24.498  -25.019  1.00 52.12  ? 324  ASP B O   1 
ATOM   5963  C CB  . ASP B 1 331 ? 1.663   25.138  -27.735  1.00 55.48  ? 324  ASP B CB  1 
ATOM   5964  C CG  . ASP B 1 331 ? 2.299   26.369  -28.358  1.00 65.59  ? 324  ASP B CG  1 
ATOM   5965  O OD1 . ASP B 1 331 ? 3.075   27.051  -27.650  1.00 76.05  ? 324  ASP B OD1 1 
ATOM   5966  O OD2 . ASP B 1 331 ? 2.033   26.632  -29.545  1.00 74.48  ? 324  ASP B OD2 1 
ATOM   5967  N N   . ASN B 1 332 ? 1.279   22.653  -25.759  1.00 46.11  ? 325  ASN B N   1 
ATOM   5968  C CA  . ASN B 1 332 ? 0.480   21.613  -25.058  1.00 40.88  ? 325  ASN B CA  1 
ATOM   5969  C C   . ASN B 1 332 ? 1.440   20.652  -24.366  1.00 38.37  ? 325  ASN B C   1 
ATOM   5970  O O   . ASN B 1 332 ? 1.896   19.670  -24.943  1.00 34.95  ? 325  ASN B O   1 
ATOM   5971  C CB  . ASN B 1 332 ? -0.488  20.861  -25.970  1.00 37.32  ? 325  ASN B CB  1 
ATOM   5972  C CG  . ASN B 1 332 ? -1.366  19.902  -25.190  1.00 36.23  ? 325  ASN B CG  1 
ATOM   5973  O OD1 . ASN B 1 332 ? -1.369  19.914  -23.957  1.00 38.18  ? 325  ASN B OD1 1 
ATOM   5974  N ND2 . ASN B 1 332 ? -2.120  19.066  -25.884  1.00 33.76  ? 325  ASN B ND2 1 
ATOM   5975  N N   . PRO B 1 333 ? 1.747   20.902  -23.083  1.00 37.24  ? 326  PRO B N   1 
ATOM   5976  C CA  . PRO B 1 333 ? 2.680   20.053  -22.341  1.00 34.82  ? 326  PRO B CA  1 
ATOM   5977  C C   . PRO B 1 333 ? 2.130   18.657  -22.001  1.00 32.21  ? 326  PRO B C   1 
ATOM   5978  O O   . PRO B 1 333 ? 2.868   17.872  -21.445  1.00 29.09  ? 326  PRO B O   1 
ATOM   5979  C CB  . PRO B 1 333 ? 2.941   20.886  -21.082  1.00 35.94  ? 326  PRO B CB  1 
ATOM   5980  C CG  . PRO B 1 333 ? 1.653   21.669  -20.886  1.00 38.51  ? 326  PRO B CG  1 
ATOM   5981  C CD  . PRO B 1 333 ? 1.217   22.021  -22.290  1.00 37.00  ? 326  PRO B CD  1 
ATOM   5982  N N   . PHE B 1 334 ? 0.886   18.352  -22.375  1.00 31.65  ? 327  PHE B N   1 
ATOM   5983  C CA  . PHE B 1 334 ? 0.295   17.006  -22.166  1.00 35.78  ? 327  PHE B CA  1 
ATOM   5984  C C   . PHE B 1 334 ? 0.377   16.202  -23.455  1.00 34.96  ? 327  PHE B C   1 
ATOM   5985  O O   . PHE B 1 334 ? -0.113  15.075  -23.486  1.00 38.75  ? 327  PHE B O   1 
ATOM   5986  C CB  . PHE B 1 334 ? -1.137  17.121  -21.641  1.00 40.21  ? 327  PHE B CB  1 
ATOM   5987  C CG  . PHE B 1 334 ? -1.160  17.881  -20.345  1.00 45.16  ? 327  PHE B CG  1 
ATOM   5988  C CD1 . PHE B 1 334 ? -0.598  17.326  -19.201  1.00 46.90  ? 327  PHE B CD1 1 
ATOM   5989  C CD2 . PHE B 1 334 ? -1.627  19.186  -20.299  1.00 47.48  ? 327  PHE B CD2 1 
ATOM   5990  C CE1 . PHE B 1 334 ? -0.549  18.048  -18.021  1.00 48.87  ? 327  PHE B CE1 1 
ATOM   5991  C CE2 . PHE B 1 334 ? -1.590  19.900  -19.112  1.00 51.06  ? 327  PHE B CE2 1 
ATOM   5992  C CZ  . PHE B 1 334 ? -1.050  19.329  -17.978  1.00 52.70  ? 327  PHE B CZ  1 
ATOM   5993  N N   . LEU B 1 335 ? 1.015   16.750  -24.475  1.00 31.25  ? 328  LEU B N   1 
ATOM   5994  C CA  . LEU B 1 335 ? 1.094   16.076  -25.782  1.00 32.36  ? 328  LEU B CA  1 
ATOM   5995  C C   . LEU B 1 335 ? 1.796   14.728  -25.621  1.00 30.40  ? 328  LEU B C   1 
ATOM   5996  O O   . LEU B 1 335 ? 1.372   13.744  -26.257  1.00 28.61  ? 328  LEU B O   1 
ATOM   5997  C CB  . LEU B 1 335 ? 1.844   17.011  -26.725  1.00 34.52  ? 328  LEU B CB  1 
ATOM   5998  C CG  . LEU B 1 335 ? 1.522   16.840  -28.199  1.00 35.20  ? 328  LEU B CG  1 
ATOM   5999  C CD1 . LEU B 1 335 ? 0.007   16.715  -28.407  1.00 34.69  ? 328  LEU B CD1 1 
ATOM   6000  C CD2 . LEU B 1 335 ? 2.133   18.000  -28.994  1.00 37.17  ? 328  LEU B CD2 1 
ATOM   6001  N N   . HIS B 1 336 ? 2.855   14.704  -24.816  1.00 30.37  ? 329  HIS B N   1 
ATOM   6002  C CA  . HIS B 1 336 ? 3.589   13.476  -24.416  1.00 31.28  ? 329  HIS B CA  1 
ATOM   6003  C C   . HIS B 1 336 ? 3.808   13.522  -22.906  1.00 31.41  ? 329  HIS B C   1 
ATOM   6004  O O   . HIS B 1 336 ? 4.353   14.532  -22.402  1.00 30.76  ? 329  HIS B O   1 
ATOM   6005  C CB  . HIS B 1 336 ? 4.923   13.298  -25.179  1.00 30.32  ? 329  HIS B CB  1 
ATOM   6006  C CG  . HIS B 1 336 ? 5.502   11.928  -25.018  1.00 28.90  ? 329  HIS B CG  1 
ATOM   6007  N ND1 . HIS B 1 336 ? 4.805   10.776  -25.354  1.00 28.07  ? 329  HIS B ND1 1 
ATOM   6008  C CD2 . HIS B 1 336 ? 6.692   11.503  -24.554  1.00 26.08  ? 329  HIS B CD2 1 
ATOM   6009  C CE1 . HIS B 1 336 ? 5.542   9.713   -25.095  1.00 26.99  ? 329  HIS B CE1 1 
ATOM   6010  N NE2 . HIS B 1 336 ? 6.708   10.132  -24.617  1.00 25.66  ? 329  HIS B NE2 1 
ATOM   6011  N N   . THR B 1 337 ? 3.380   12.462  -22.222  1.00 32.49  ? 330  THR B N   1 
ATOM   6012  C CA  . THR B 1 337 ? 3.459   12.286  -20.751  1.00 31.99  ? 330  THR B CA  1 
ATOM   6013  C C   . THR B 1 337 ? 3.655   10.801  -20.442  1.00 31.47  ? 330  THR B C   1 
ATOM   6014  O O   . THR B 1 337 ? 3.489   9.966   -21.348  1.00 28.73  ? 330  THR B O   1 
ATOM   6015  C CB  . THR B 1 337 ? 2.188   12.834  -20.081  1.00 34.38  ? 330  THR B CB  1 
ATOM   6016  O OG1 . THR B 1 337 ? 1.031   12.106  -20.510  1.00 29.90  ? 330  THR B OG1 1 
ATOM   6017  C CG2 . THR B 1 337 ? 1.961   14.300  -20.392  1.00 35.42  ? 330  THR B CG2 1 
ATOM   6018  N N   . THR B 1 338 ? 4.021   10.492  -19.203  1.00 35.71  ? 331  THR B N   1 
ATOM   6019  C CA  . THR B 1 338 ? 4.018   9.125   -18.616  1.00 36.67  ? 331  THR B CA  1 
ATOM   6020  C C   . THR B 1 338 ? 3.730   9.349   -17.134  1.00 35.45  ? 331  THR B C   1 
ATOM   6021  O O   . THR B 1 338 ? 3.970   10.469  -16.637  1.00 35.59  ? 331  THR B O   1 
ATOM   6022  C CB  . THR B 1 338 ? 5.304   8.347   -18.972  1.00 37.23  ? 331  THR B CB  1 
ATOM   6023  O OG1 . THR B 1 338 ? 5.173   6.935   -18.800  1.00 36.12  ? 331  THR B OG1 1 
ATOM   6024  C CG2 . THR B 1 338 ? 6.485   8.780   -18.152  1.00 35.73  ? 331  THR B CG2 1 
ATOM   6025  N N   A THR B 1 339 ? 3.193   8.335   -16.458  0.50 36.32  ? 332  THR B N   1 
ATOM   6026  N N   B THR B 1 339 ? 3.192   8.332   -16.462  0.50 33.08  ? 332  THR B N   1 
ATOM   6027  C CA  A THR B 1 339 ? 2.755   8.420   -15.042  0.50 37.60  ? 332  THR B CA  1 
ATOM   6028  C CA  B THR B 1 339 ? 2.744   8.401   -15.047  0.50 32.30  ? 332  THR B CA  1 
ATOM   6029  C C   A THR B 1 339 ? 3.991   8.370   -14.136  0.50 33.91  ? 332  THR B C   1 
ATOM   6030  C C   B THR B 1 339 ? 3.984   8.363   -14.136  0.50 31.13  ? 332  THR B C   1 
ATOM   6031  O O   A THR B 1 339 ? 4.139   9.264   -13.284  0.50 32.67  ? 332  THR B O   1 
ATOM   6032  O O   B THR B 1 339 ? 4.132   9.258   -13.282  0.50 30.22  ? 332  THR B O   1 
ATOM   6033  C CB  A THR B 1 339 ? 1.684   7.355   -14.780  0.50 40.83  ? 332  THR B CB  1 
ATOM   6034  C CB  B THR B 1 339 ? 1.697   7.301   -14.800  0.50 31.53  ? 332  THR B CB  1 
ATOM   6035  O OG1 A THR B 1 339 ? 2.205   6.100   -15.212  0.50 46.68  ? 332  THR B OG1 1 
ATOM   6036  O OG1 B THR B 1 339 ? 0.483   7.623   -15.492  0.50 31.11  ? 332  THR B OG1 1 
ATOM   6037  C CG2 A THR B 1 339 ? 0.402   7.663   -15.523  0.50 40.77  ? 332  THR B CG2 1 
ATOM   6038  C CG2 B THR B 1 339 ? 1.406   7.077   -13.334  0.50 29.13  ? 332  THR B CG2 1 
ATOM   6039  N N   . PHE B 1 340 ? 4.870   7.391   -14.346  1.00 30.19  ? 333  PHE B N   1 
ATOM   6040  C CA  . PHE B 1 340 ? 6.040   7.134   -13.471  1.00 29.86  ? 333  PHE B CA  1 
ATOM   6041  C C   . PHE B 1 340 ? 7.295   7.927   -13.881  1.00 26.54  ? 333  PHE B C   1 
ATOM   6042  O O   . PHE B 1 340 ? 8.233   7.978   -13.094  1.00 24.24  ? 333  PHE B O   1 
ATOM   6043  C CB  . PHE B 1 340 ? 6.345   5.639   -13.496  1.00 29.56  ? 333  PHE B CB  1 
ATOM   6044  C CG  . PHE B 1 340 ? 5.248   4.737   -12.976  1.00 28.45  ? 333  PHE B CG  1 
ATOM   6045  C CD1 . PHE B 1 340 ? 4.703   4.937   -11.715  1.00 26.64  ? 333  PHE B CD1 1 
ATOM   6046  C CD2 . PHE B 1 340 ? 4.825   3.641   -13.712  1.00 26.78  ? 333  PHE B CD2 1 
ATOM   6047  C CE1 . PHE B 1 340 ? 3.745   4.072   -11.212  1.00 25.80  ? 333  PHE B CE1 1 
ATOM   6048  C CE2 . PHE B 1 340 ? 3.863   2.784   -13.208  1.00 25.97  ? 333  PHE B CE2 1 
ATOM   6049  C CZ  . PHE B 1 340 ? 3.332   2.994   -11.957  1.00 25.76  ? 333  PHE B CZ  1 
ATOM   6050  N N   . GLY B 1 341 ? 7.324   8.514   -15.077  1.00 26.61  ? 334  GLY B N   1 
ATOM   6051  C CA  . GLY B 1 341 ? 8.556   9.068   -15.681  1.00 26.57  ? 334  GLY B CA  1 
ATOM   6052  C C   . GLY B 1 341 ? 9.064   10.273  -14.914  1.00 26.72  ? 334  GLY B C   1 
ATOM   6053  O O   . GLY B 1 341 ? 8.254   11.144  -14.585  1.00 28.60  ? 334  GLY B O   1 
ATOM   6054  N N   . GLY B 1 342 ? 10.355  10.320  -14.621  1.00 24.81  ? 335  GLY B N   1 
ATOM   6055  C CA  . GLY B 1 342 ? 10.963  11.426  -13.861  1.00 26.33  ? 335  GLY B CA  1 
ATOM   6056  C C   . GLY B 1 342 ? 10.574  11.385  -12.392  1.00 26.92  ? 335  GLY B C   1 
ATOM   6057  O O   . GLY B 1 342 ? 10.670  12.445  -11.734  1.00 29.08  ? 335  GLY B O   1 
ATOM   6058  N N   . ASN B 1 343 ? 10.189  10.211  -11.874  1.00 24.98  ? 336  ASN B N   1 
ATOM   6059  C CA  . ASN B 1 343 ? 9.869   10.038  -10.436  1.00 23.47  ? 336  ASN B CA  1 
ATOM   6060  C C   . ASN B 1 343 ? 11.116  10.337  -9.605   1.00 22.41  ? 336  ASN B C   1 
ATOM   6061  O O   . ASN B 1 343 ? 12.246  10.191  -10.057  1.00 20.54  ? 336  ASN B O   1 
ATOM   6062  C CB  . ASN B 1 343 ? 9.243   8.677   -10.106  1.00 23.92  ? 336  ASN B CB  1 
ATOM   6063  C CG  . ASN B 1 343 ? 10.192  7.508   -10.223  1.00 23.89  ? 336  ASN B CG  1 
ATOM   6064  O OD1 . ASN B 1 343 ? 10.996  7.255   -9.323   1.00 25.91  ? 336  ASN B OD1 1 
ATOM   6065  N ND2 . ASN B 1 343 ? 10.074  6.773   -11.311  1.00 23.11  ? 336  ASN B ND2 1 
ATOM   6066  N N   . PRO B 1 344 ? 10.918  10.835  -8.369   1.00 20.49  ? 337  PRO B N   1 
ATOM   6067  C CA  . PRO B 1 344 ? 12.029  11.170  -7.482   1.00 19.84  ? 337  PRO B CA  1 
ATOM   6068  C C   . PRO B 1 344 ? 13.054  10.064  -7.167   1.00 19.68  ? 337  PRO B C   1 
ATOM   6069  O O   . PRO B 1 344 ? 14.222  10.402  -7.122   1.00 18.56  ? 337  PRO B O   1 
ATOM   6070  C CB  . PRO B 1 344 ? 11.301  11.585  -6.200   1.00 20.00  ? 337  PRO B CB  1 
ATOM   6071  C CG  . PRO B 1 344 ? 9.977   12.135  -6.688   1.00 20.34  ? 337  PRO B CG  1 
ATOM   6072  C CD  . PRO B 1 344 ? 9.599   11.201  -7.814   1.00 19.87  ? 337  PRO B CD  1 
ATOM   6073  N N   . LEU B 1 345 ? 12.647  8.809   -6.941   1.00 19.86  ? 338  LEU B N   1 
ATOM   6074  C CA  . LEU B 1 345 ? 13.614  7.688   -6.757   1.00 21.10  ? 338  LEU B CA  1 
ATOM   6075  C C   . LEU B 1 345 ? 14.516  7.596   -7.993   1.00 22.81  ? 338  LEU B C   1 
ATOM   6076  O O   . LEU B 1 345 ? 15.744  7.557   -7.857   1.00 20.36  ? 338  LEU B O   1 
ATOM   6077  C CB  . LEU B 1 345 ? 12.888  6.351   -6.597   1.00 22.62  ? 338  LEU B CB  1 
ATOM   6078  C CG  . LEU B 1 345 ? 12.213  6.076   -5.257   1.00 25.00  ? 338  LEU B CG  1 
ATOM   6079  C CD1 . LEU B 1 345 ? 11.953  4.589   -5.089   1.00 25.84  ? 338  LEU B CD1 1 
ATOM   6080  C CD2 . LEU B 1 345 ? 13.048  6.579   -4.095   1.00 27.37  ? 338  LEU B CD2 1 
ATOM   6081  N N   . ALA B 1 346 ? 13.903  7.509   -9.177   1.00 23.48  ? 339  ALA B N   1 
ATOM   6082  C CA  . ALA B 1 346 ? 14.654  7.356   -10.430  1.00 22.62  ? 339  ALA B CA  1 
ATOM   6083  C C   . ALA B 1 346 ? 15.603  8.552   -10.565  1.00 23.77  ? 339  ALA B C   1 
ATOM   6084  O O   . ALA B 1 346 ? 16.778  8.290   -10.875  1.00 24.50  ? 339  ALA B O   1 
ATOM   6085  C CB  . ALA B 1 346 ? 13.731  7.223   -11.610  1.00 22.93  ? 339  ALA B CB  1 
ATOM   6086  N N   . CYS B 1 347 ? 15.134  9.793   -10.340  1.00 22.69  ? 340  CYS B N   1 
ATOM   6087  C CA  . CYS B 1 347 ? 15.946  11.038  -10.510  1.00 23.32  ? 340  CYS B CA  1 
ATOM   6088  C C   . CYS B 1 347 ? 17.130  11.016  -9.536   1.00 23.29  ? 340  CYS B C   1 
ATOM   6089  O O   . CYS B 1 347 ? 18.285  11.257  -9.971   1.00 26.12  ? 340  CYS B O   1 
ATOM   6090  C CB  . CYS B 1 347 ? 15.120  12.298  -10.287  1.00 23.24  ? 340  CYS B CB  1 
ATOM   6091  S SG  . CYS B 1 347 ? 13.992  12.677  -11.651  1.00 24.55  ? 340  CYS B SG  1 
ATOM   6092  N N   . ALA B 1 348 ? 16.848  10.711  -8.274   1.00 22.40  ? 341  ALA B N   1 
ATOM   6093  C CA  . ALA B 1 348 ? 17.868  10.516  -7.230   1.00 24.47  ? 341  ALA B CA  1 
ATOM   6094  C C   . ALA B 1 348 ? 18.925  9.533   -7.736   1.00 24.63  ? 341  ALA B C   1 
ATOM   6095  O O   . ALA B 1 348 ? 20.121  9.858   -7.619   1.00 27.05  ? 341  ALA B O   1 
ATOM   6096  C CB  . ALA B 1 348 ? 17.227  10.035  -5.946   1.00 25.51  ? 341  ALA B CB  1 
ATOM   6097  N N   . ALA B 1 349 ? 18.506  8.387   -8.287   1.00 22.90  ? 342  ALA B N   1 
ATOM   6098  C CA  . ALA B 1 349 ? 19.412  7.299   -8.737   1.00 21.53  ? 342  ALA B CA  1 
ATOM   6099  C C   . ALA B 1 349 ? 20.297  7.817   -9.871   1.00 20.09  ? 342  ALA B C   1 
ATOM   6100  O O   . ALA B 1 349 ? 21.527  7.559   -9.849   1.00 20.22  ? 342  ALA B O   1 
ATOM   6101  C CB  . ALA B 1 349 ? 18.626  6.083   -9.155   1.00 21.47  ? 342  ALA B CB  1 
ATOM   6102  N N   . ALA B 1 350 ? 19.704  8.541   -10.816  1.00 18.93  ? 343  ALA B N   1 
ATOM   6103  C CA  . ALA B 1 350 ? 20.424  9.080   -11.985  1.00 19.56  ? 343  ALA B CA  1 
ATOM   6104  C C   . ALA B 1 350 ? 21.402  10.163  -11.507  1.00 20.39  ? 343  ALA B C   1 
ATOM   6105  O O   . ALA B 1 350 ? 22.546  10.170  -12.014  1.00 20.21  ? 343  ALA B O   1 
ATOM   6106  C CB  . ALA B 1 350 ? 19.480  9.607   -13.019  1.00 18.53  ? 343  ALA B CB  1 
ATOM   6107  N N   . LEU B 1 351 ? 20.976  11.034  -10.584  1.00 19.36  ? 344  LEU B N   1 
ATOM   6108  C CA  . LEU B 1 351 ? 21.798  12.182  -10.140  1.00 19.61  ? 344  LEU B CA  1 
ATOM   6109  C C   . LEU B 1 351 ? 23.037  11.626  -9.438   1.00 18.94  ? 344  LEU B C   1 
ATOM   6110  O O   . LEU B 1 351 ? 24.161  12.146  -9.662   1.00 18.05  ? 344  LEU B O   1 
ATOM   6111  C CB  . LEU B 1 351 ? 20.968  13.063  -9.211   1.00 20.99  ? 344  LEU B CB  1 
ATOM   6112  C CG  . LEU B 1 351 ? 19.970  13.970  -9.924   1.00 23.05  ? 344  LEU B CG  1 
ATOM   6113  C CD1 . LEU B 1 351 ? 18.823  14.402  -9.013   1.00 23.31  ? 344  LEU B CD1 1 
ATOM   6114  C CD2 . LEU B 1 351 ? 20.684  15.176  -10.505  1.00 23.61  ? 344  LEU B CD2 1 
ATOM   6115  N N   . ALA B 1 352 ? 22.832  10.576  -8.647   1.00 20.07  ? 345  ALA B N   1 
ATOM   6116  C CA  . ALA B 1 352 ? 23.908  9.844   -7.939   1.00 21.13  ? 345  ALA B CA  1 
ATOM   6117  C C   . ALA B 1 352 ? 24.852  9.250   -8.977   1.00 21.57  ? 345  ALA B C   1 
ATOM   6118  O O   . ALA B 1 352 ? 26.062  9.423   -8.837   1.00 22.77  ? 345  ALA B O   1 
ATOM   6119  C CB  . ALA B 1 352 ? 23.339  8.764   -7.043   1.00 22.32  ? 345  ALA B CB  1 
ATOM   6120  N N   . THR B 1 353 ? 24.306  8.579   -9.988   1.00 21.41  ? 346  THR B N   1 
ATOM   6121  C CA  . THR B 1 353 ? 25.079  7.861   -11.030  1.00 19.78  ? 346  THR B CA  1 
ATOM   6122  C C   . THR B 1 353 ? 26.001  8.845   -11.736  1.00 19.52  ? 346  THR B C   1 
ATOM   6123  O O   . THR B 1 353 ? 27.186  8.525   -11.842  1.00 16.05  ? 346  THR B O   1 
ATOM   6124  C CB  . THR B 1 353 ? 24.153  7.165   -12.022  1.00 19.93  ? 346  THR B CB  1 
ATOM   6125  O OG1 . THR B 1 353 ? 23.274  6.336   -11.253  1.00 23.44  ? 346  THR B OG1 1 
ATOM   6126  C CG2 . THR B 1 353 ? 24.915  6.348   -13.032  1.00 19.94  ? 346  THR B CG2 1 
ATOM   6127  N N   . ILE B 1 354 ? 25.475  9.987   -12.179  1.00 20.58  ? 347  ILE B N   1 
ATOM   6128  C CA  . ILE B 1 354 ? 26.290  11.061  -12.826  1.00 22.66  ? 347  ILE B CA  1 
ATOM   6129  C C   . ILE B 1 354 ? 27.374  11.517  -11.858  1.00 22.49  ? 347  ILE B C   1 
ATOM   6130  O O   . ILE B 1 354 ? 28.534  11.645  -12.272  1.00 24.69  ? 347  ILE B O   1 
ATOM   6131  C CB  . ILE B 1 354 ? 25.419  12.250  -13.255  1.00 23.49  ? 347  ILE B CB  1 
ATOM   6132  C CG1 . ILE B 1 354 ? 24.521  11.872  -14.427  1.00 24.40  ? 347  ILE B CG1 1 
ATOM   6133  C CG2 . ILE B 1 354 ? 26.274  13.466  -13.583  1.00 23.20  ? 347  ILE B CG2 1 
ATOM   6134  C CD1 . ILE B 1 354 ? 23.267  12.721  -14.523  1.00 25.88  ? 347  ILE B CD1 1 
ATOM   6135  N N   . ASN B 1 355 ? 27.002  11.787  -10.611  1.00 25.31  ? 348  ASN B N   1 
ATOM   6136  C CA  . ASN B 1 355 ? 27.989  12.226  -9.598   1.00 24.87  ? 348  ASN B CA  1 
ATOM   6137  C C   . ASN B 1 355 ? 29.128  11.200  -9.507   1.00 24.52  ? 348  ASN B C   1 
ATOM   6138  O O   . ASN B 1 355 ? 30.295  11.629  -9.498   1.00 22.97  ? 348  ASN B O   1 
ATOM   6139  C CB  . ASN B 1 355 ? 27.374  12.450  -8.226   1.00 26.81  ? 348  ASN B CB  1 
ATOM   6140  C CG  . ASN B 1 355 ? 28.364  13.132  -7.309   1.00 27.34  ? 348  ASN B CG  1 
ATOM   6141  O OD1 . ASN B 1 355 ? 29.023  12.480  -6.497   1.00 27.99  ? 348  ASN B OD1 1 
ATOM   6142  N ND2 . ASN B 1 355 ? 28.534  14.431  -7.501   1.00 28.91  ? 348  ASN B ND2 1 
ATOM   6143  N N   . VAL B 1 356 ? 28.797  9.903   -9.438   1.00 23.41  ? 349  VAL B N   1 
ATOM   6144  C CA  . VAL B 1 356 ? 29.778  8.789   -9.260   1.00 22.47  ? 349  VAL B CA  1 
ATOM   6145  C C   . VAL B 1 356 ? 30.689  8.738   -10.486  1.00 22.34  ? 349  VAL B C   1 
ATOM   6146  O O   . VAL B 1 356 ? 31.914  8.710   -10.305  1.00 19.34  ? 349  VAL B O   1 
ATOM   6147  C CB  . VAL B 1 356 ? 29.069  7.441   -9.019   1.00 22.50  ? 349  VAL B CB  1 
ATOM   6148  C CG1 . VAL B 1 356 ? 29.978  6.244   -9.222   1.00 22.18  ? 349  VAL B CG1 1 
ATOM   6149  C CG2 . VAL B 1 356 ? 28.463  7.387   -7.632   1.00 23.54  ? 349  VAL B CG2 1 
ATOM   6150  N N   . LEU B 1 357 ? 30.111  8.724   -11.691  1.00 23.43  ? 350  LEU B N   1 
ATOM   6151  C CA  . LEU B 1 357 ? 30.881  8.572   -12.954  1.00 23.23  ? 350  LEU B CA  1 
ATOM   6152  C C   . LEU B 1 357 ? 31.909  9.699   -13.072  1.00 22.80  ? 350  LEU B C   1 
ATOM   6153  O O   . LEU B 1 357 ? 33.046  9.398   -13.466  1.00 20.74  ? 350  LEU B O   1 
ATOM   6154  C CB  . LEU B 1 357 ? 29.921  8.556   -14.148  1.00 22.66  ? 350  LEU B CB  1 
ATOM   6155  C CG  . LEU B 1 357 ? 29.085  7.283   -14.299  1.00 23.12  ? 350  LEU B CG  1 
ATOM   6156  C CD1 . LEU B 1 357 ? 27.962  7.509   -15.290  1.00 23.64  ? 350  LEU B CD1 1 
ATOM   6157  C CD2 . LEU B 1 357 ? 29.919  6.083   -14.734  1.00 23.94  ? 350  LEU B CD2 1 
ATOM   6158  N N   . LEU B 1 358 ? 31.519  10.933  -12.749  1.00 24.21  ? 351  LEU B N   1 
ATOM   6159  C CA  . LEU B 1 358 ? 32.380  12.132  -12.894  1.00 26.00  ? 351  LEU B CA  1 
ATOM   6160  C C   . LEU B 1 358 ? 33.427  12.159  -11.778  1.00 28.51  ? 351  LEU B C   1 
ATOM   6161  O O   . LEU B 1 358 ? 34.611  12.281  -12.115  1.00 27.52  ? 351  LEU B O   1 
ATOM   6162  C CB  . LEU B 1 358 ? 31.509  13.390  -12.892  1.00 26.84  ? 351  LEU B CB  1 
ATOM   6163  C CG  . LEU B 1 358 ? 30.622  13.541  -14.122  1.00 28.99  ? 351  LEU B CG  1 
ATOM   6164  C CD1 . LEU B 1 358 ? 29.838  14.848  -14.098  1.00 29.79  ? 351  LEU B CD1 1 
ATOM   6165  C CD2 . LEU B 1 358 ? 31.460  13.452  -15.391  1.00 29.95  ? 351  LEU B CD2 1 
ATOM   6166  N N   . GLU B 1 359 ? 33.013  12.018  -10.515  1.00 31.49  ? 352  GLU B N   1 
ATOM   6167  C CA  . GLU B 1 359 ? 33.910  12.040  -9.324   1.00 34.52  ? 352  GLU B CA  1 
ATOM   6168  C C   . GLU B 1 359 ? 35.047  11.043  -9.494   1.00 33.15  ? 352  GLU B C   1 
ATOM   6169  O O   . GLU B 1 359 ? 36.185  11.448  -9.205   1.00 38.90  ? 352  GLU B O   1 
ATOM   6170  C CB  . GLU B 1 359 ? 33.209  11.644  -8.027   1.00 41.05  ? 352  GLU B CB  1 
ATOM   6171  C CG  . GLU B 1 359 ? 32.534  12.811  -7.314   1.00 48.90  ? 352  GLU B CG  1 
ATOM   6172  C CD  . GLU B 1 359 ? 33.442  13.643  -6.396   1.00 56.90  ? 352  GLU B CD  1 
ATOM   6173  O OE1 . GLU B 1 359 ? 34.590  13.963  -6.781   1.00 59.16  ? 352  GLU B OE1 1 
ATOM   6174  O OE2 . GLU B 1 359 ? 33.004  13.975  -5.283   1.00 60.94  ? 352  GLU B OE2 1 
ATOM   6175  N N   . GLN B 1 360 ? 34.747  9.811   -9.920   1.00 29.43  ? 353  GLN B N   1 
ATOM   6176  C CA  . GLN B 1 360 ? 35.724  8.691   -9.987   1.00 28.49  ? 353  GLN B CA  1 
ATOM   6177  C C   . GLN B 1 360 ? 36.299  8.497   -11.389  1.00 27.81  ? 353  GLN B C   1 
ATOM   6178  O O   . GLN B 1 360 ? 37.045  7.538   -11.548  1.00 28.60  ? 353  GLN B O   1 
ATOM   6179  C CB  . GLN B 1 360 ? 35.078  7.376   -9.581   1.00 27.75  ? 353  GLN B CB  1 
ATOM   6180  C CG  . GLN B 1 360 ? 34.493  7.398   -8.188   1.00 30.47  ? 353  GLN B CG  1 
ATOM   6181  C CD  . GLN B 1 360 ? 33.954  6.025   -7.856   1.00 32.58  ? 353  GLN B CD  1 
ATOM   6182  O OE1 . GLN B 1 360 ? 34.464  4.996   -8.312   1.00 33.39  ? 353  GLN B OE1 1 
ATOM   6183  N NE2 . GLN B 1 360 ? 32.884  5.995   -7.076   1.00 34.53  ? 353  GLN B NE2 1 
ATOM   6184  N N   . ASN B 1 361 ? 35.965  9.356   -12.353  1.00 30.55  ? 354  ASN B N   1 
ATOM   6185  C CA  . ASN B 1 361 ? 36.481  9.302   -13.755  1.00 31.83  ? 354  ASN B CA  1 
ATOM   6186  C C   . ASN B 1 361 ? 36.332  7.878   -14.299  1.00 28.69  ? 354  ASN B C   1 
ATOM   6187  O O   . ASN B 1 361 ? 37.277  7.381   -14.916  1.00 32.81  ? 354  ASN B O   1 
ATOM   6188  C CB  . ASN B 1 361 ? 37.965  9.707   -13.857  1.00 38.14  ? 354  ASN B CB  1 
ATOM   6189  C CG  . ASN B 1 361 ? 38.253  11.169  -13.597  1.00 43.20  ? 354  ASN B CG  1 
ATOM   6190  O OD1 . ASN B 1 361 ? 38.315  11.971  -14.543  1.00 51.16  ? 354  ASN B OD1 1 
ATOM   6191  N ND2 . ASN B 1 361 ? 38.538  11.498  -12.340  1.00 44.97  ? 354  ASN B ND2 1 
ATOM   6192  N N   . LEU B 1 362 ? 35.179  7.244   -14.099  1.00 28.60  ? 355  LEU B N   1 
ATOM   6193  C CA  . LEU B 1 362 ? 34.929  5.852   -14.562  1.00 29.07  ? 355  LEU B CA  1 
ATOM   6194  C C   . LEU B 1 362 ? 34.934  5.741   -16.095  1.00 27.47  ? 355  LEU B C   1 
ATOM   6195  O O   . LEU B 1 362 ? 35.255  4.679   -16.625  1.00 23.98  ? 355  LEU B O   1 
ATOM   6196  C CB  . LEU B 1 362 ? 33.613  5.359   -13.963  1.00 31.20  ? 355  LEU B CB  1 
ATOM   6197  C CG  . LEU B 1 362 ? 33.751  4.752   -12.570  1.00 33.68  ? 355  LEU B CG  1 
ATOM   6198  C CD1 . LEU B 1 362 ? 32.398  4.698   -11.859  1.00 38.42  ? 355  LEU B CD1 1 
ATOM   6199  C CD2 . LEU B 1 362 ? 34.359  3.364   -12.653  1.00 33.03  ? 355  LEU B CD2 1 
ATOM   6200  N N   . PRO B 1 363 ? 34.576  6.788   -16.880  1.00 25.97  ? 356  PRO B N   1 
ATOM   6201  C CA  . PRO B 1 363 ? 34.807  6.761   -18.323  1.00 25.29  ? 356  PRO B CA  1 
ATOM   6202  C C   . PRO B 1 363 ? 36.273  6.441   -18.646  1.00 25.56  ? 356  PRO B C   1 
ATOM   6203  O O   . PRO B 1 363 ? 36.545  5.522   -19.392  1.00 24.58  ? 356  PRO B O   1 
ATOM   6204  C CB  . PRO B 1 363 ? 34.392  8.172   -18.770  1.00 25.31  ? 356  PRO B CB  1 
ATOM   6205  C CG  . PRO B 1 363 ? 33.331  8.556   -17.781  1.00 25.41  ? 356  PRO B CG  1 
ATOM   6206  C CD  . PRO B 1 363 ? 33.857  8.007   -16.467  1.00 25.87  ? 356  PRO B CD  1 
ATOM   6207  N N   . ALA B 1 364 ? 37.199  7.173   -18.050  1.00 27.17  ? 357  ALA B N   1 
ATOM   6208  C CA  . ALA B 1 364 ? 38.644  6.918   -18.226  1.00 25.57  ? 357  ALA B CA  1 
ATOM   6209  C C   . ALA B 1 364 ? 38.972  5.474   -17.810  1.00 24.48  ? 357  ALA B C   1 
ATOM   6210  O O   . ALA B 1 364 ? 39.771  4.836   -18.511  1.00 24.81  ? 357  ALA B O   1 
ATOM   6211  C CB  . ALA B 1 364 ? 39.434  7.935   -17.448  1.00 25.45  ? 357  ALA B CB  1 
ATOM   6212  N N   . GLN B 1 365 ? 38.371  4.954   -16.735  1.00 23.13  ? 358  GLN B N   1 
ATOM   6213  C CA  . GLN B 1 365 ? 38.664  3.574   -16.257  1.00 23.27  ? 358  GLN B CA  1 
ATOM   6214  C C   . GLN B 1 365 ? 38.183  2.569   -17.307  1.00 23.30  ? 358  GLN B C   1 
ATOM   6215  O O   . GLN B 1 365 ? 38.883  1.568   -17.548  1.00 23.36  ? 358  GLN B O   1 
ATOM   6216  C CB  . GLN B 1 365 ? 38.012  3.283   -14.906  1.00 23.39  ? 358  GLN B CB  1 
ATOM   6217  C CG  . GLN B 1 365 ? 38.605  4.081   -13.765  1.00 24.28  ? 358  GLN B CG  1 
ATOM   6218  C CD  . GLN B 1 365 ? 38.059  3.648   -12.430  1.00 26.25  ? 358  GLN B CD  1 
ATOM   6219  O OE1 . GLN B 1 365 ? 37.967  2.465   -12.088  1.00 27.06  ? 358  GLN B OE1 1 
ATOM   6220  N NE2 . GLN B 1 365 ? 37.705  4.633   -11.633  1.00 28.90  ? 358  GLN B NE2 1 
ATOM   6221  N N   . ALA B 1 366 ? 37.015  2.815   -17.888  1.00 23.33  ? 359  ALA B N   1 
ATOM   6222  C CA  . ALA B 1 366 ? 36.402  1.918   -18.888  1.00 26.06  ? 359  ALA B CA  1 
ATOM   6223  C C   . ALA B 1 366 ? 37.361  1.796   -20.069  1.00 27.93  ? 359  ALA B C   1 
ATOM   6224  O O   . ALA B 1 366 ? 37.590  0.658   -20.539  1.00 26.84  ? 359  ALA B O   1 
ATOM   6225  C CB  . ALA B 1 366 ? 35.049  2.443   -19.315  1.00 26.66  ? 359  ALA B CB  1 
ATOM   6226  N N   . GLU B 1 367 ? 37.917  2.929   -20.506  1.00 32.22  ? 360  GLU B N   1 
ATOM   6227  C CA  . GLU B 1 367 ? 38.932  2.991   -21.592  1.00 35.53  ? 360  GLU B CA  1 
ATOM   6228  C C   . GLU B 1 367 ? 40.092  2.049   -21.257  1.00 31.58  ? 360  GLU B C   1 
ATOM   6229  O O   . GLU B 1 367 ? 40.389  1.157   -22.091  1.00 30.12  ? 360  GLU B O   1 
ATOM   6230  C CB  . GLU B 1 367 ? 39.442  4.421   -21.811  1.00 40.47  ? 360  GLU B CB  1 
ATOM   6231  C CG  . GLU B 1 367 ? 40.232  4.540   -23.102  1.00 44.76  ? 360  GLU B CG  1 
ATOM   6232  C CD  . GLU B 1 367 ? 40.854  5.882   -23.414  1.00 52.95  ? 360  GLU B CD  1 
ATOM   6233  O OE1 . GLU B 1 367 ? 40.436  6.870   -22.787  1.00 60.58  ? 360  GLU B OE1 1 
ATOM   6234  O OE2 . GLU B 1 367 ? 41.752  5.922   -24.294  1.00 63.06  ? 360  GLU B OE2 1 
ATOM   6235  N N   . GLN B 1 368 ? 40.707  2.241   -20.089  1.00 30.22  ? 361  GLN B N   1 
ATOM   6236  C CA  . GLN B 1 368 ? 41.938  1.515   -19.687  1.00 32.26  ? 361  GLN B CA  1 
ATOM   6237  C C   . GLN B 1 368 ? 41.619  0.029   -19.579  1.00 28.07  ? 361  GLN B C   1 
ATOM   6238  O O   . GLN B 1 368 ? 42.356  -0.782  -20.151  1.00 27.86  ? 361  GLN B O   1 
ATOM   6239  C CB  . GLN B 1 368 ? 42.507  2.012   -18.360  1.00 37.82  ? 361  GLN B CB  1 
ATOM   6240  C CG  . GLN B 1 368 ? 43.976  1.647   -18.227  1.00 48.49  ? 361  GLN B CG  1 
ATOM   6241  C CD  . GLN B 1 368 ? 44.433  1.332   -16.826  1.00 58.81  ? 361  GLN B CD  1 
ATOM   6242  O OE1 . GLN B 1 368 ? 43.744  0.675   -16.045  1.00 59.44  ? 361  GLN B OE1 1 
ATOM   6243  N NE2 . GLN B 1 368 ? 45.640  1.780   -16.513  1.00 68.32  ? 361  GLN B NE2 1 
ATOM   6244  N N   . LYS B 1 369 ? 40.545  -0.302  -18.881  1.00 25.97  ? 362  LYS B N   1 
ATOM   6245  C CA  . LYS B 1 369 ? 40.200  -1.702  -18.530  1.00 25.37  ? 362  LYS B CA  1 
ATOM   6246  C C   . LYS B 1 369 ? 39.699  -2.423  -19.769  1.00 24.61  ? 362  LYS B C   1 
ATOM   6247  O O   . LYS B 1 369 ? 40.014  -3.608  -19.917  1.00 24.22  ? 362  LYS B O   1 
ATOM   6248  C CB  . LYS B 1 369 ? 39.173  -1.724  -17.397  1.00 24.76  ? 362  LYS B CB  1 
ATOM   6249  C CG  . LYS B 1 369 ? 39.728  -1.249  -16.058  1.00 25.35  ? 362  LYS B CG  1 
ATOM   6250  C CD  . LYS B 1 369 ? 38.654  -0.958  -15.044  1.00 26.96  ? 362  LYS B CD  1 
ATOM   6251  C CE  . LYS B 1 369 ? 39.173  -0.418  -13.731  1.00 28.91  ? 362  LYS B CE  1 
ATOM   6252  N NZ  . LYS B 1 369 ? 38.107  -0.370  -12.695  1.00 31.51  ? 362  LYS B NZ  1 
ATOM   6253  N N   . GLY B 1 370 ? 38.952  -1.721  -20.617  1.00 24.50  ? 363  GLY B N   1 
ATOM   6254  C CA  . GLY B 1 370 ? 38.487  -2.246  -21.912  1.00 24.86  ? 363  GLY B CA  1 
ATOM   6255  C C   . GLY B 1 370 ? 39.644  -2.553  -22.826  1.00 24.30  ? 363  GLY B C   1 
ATOM   6256  O O   . GLY B 1 370 ? 39.653  -3.625  -23.435  1.00 25.21  ? 363  GLY B O   1 
ATOM   6257  N N   . ASP B 1 371 ? 40.581  -1.626  -22.939  1.00 24.38  ? 364  ASP B N   1 
ATOM   6258  C CA  . ASP B 1 371 ? 41.812  -1.831  -23.739  1.00 27.40  ? 364  ASP B CA  1 
ATOM   6259  C C   . ASP B 1 371 ? 42.518  -3.094  -23.242  1.00 25.37  ? 364  ASP B C   1 
ATOM   6260  O O   . ASP B 1 371 ? 42.938  -3.922  -24.070  1.00 25.39  ? 364  ASP B O   1 
ATOM   6261  C CB  . ASP B 1 371 ? 42.707  -0.592  -23.689  1.00 30.54  ? 364  ASP B CB  1 
ATOM   6262  C CG  . ASP B 1 371 ? 42.187  0.571   -24.531  1.00 32.70  ? 364  ASP B CG  1 
ATOM   6263  O OD1 . ASP B 1 371 ? 41.175  0.396   -25.226  1.00 36.77  ? 364  ASP B OD1 1 
ATOM   6264  O OD2 . ASP B 1 371 ? 42.794  1.655   -24.485  1.00 34.57  ? 364  ASP B OD2 1 
ATOM   6265  N N   A MET B 1 372 ? 42.638  -3.230  -21.927  0.46 25.54  ? 365  MET B N   1 
ATOM   6266  N N   B MET B 1 372 ? 42.637  -3.229  -21.925  0.54 24.83  ? 365  MET B N   1 
ATOM   6267  C CA  A MET B 1 372 ? 43.313  -4.374  -21.263  0.46 26.39  ? 365  MET B CA  1 
ATOM   6268  C CA  B MET B 1 372 ? 43.312  -4.373  -21.260  0.54 25.39  ? 365  MET B CA  1 
ATOM   6269  C C   A MET B 1 372 ? 42.552  -5.663  -21.589  0.46 24.83  ? 365  MET B C   1 
ATOM   6270  C C   B MET B 1 372 ? 42.551  -5.661  -21.597  0.54 24.22  ? 365  MET B C   1 
ATOM   6271  O O   A MET B 1 372 ? 43.183  -6.599  -22.077  0.46 23.31  ? 365  MET B O   1 
ATOM   6272  O O   B MET B 1 372 ? 43.182  -6.601  -22.090  0.54 22.52  ? 365  MET B O   1 
ATOM   6273  C CB  A MET B 1 372 ? 43.356  -4.141  -19.752  0.46 27.54  ? 365  MET B CB  1 
ATOM   6274  C CB  B MET B 1 372 ? 43.360  -4.155  -19.742  0.54 25.68  ? 365  MET B CB  1 
ATOM   6275  C CG  A MET B 1 372 ? 44.024  -5.220  -18.967  0.46 28.46  ? 365  MET B CG  1 
ATOM   6276  C CG  B MET B 1 372 ? 44.018  -5.290  -18.971  0.54 25.90  ? 365  MET B CG  1 
ATOM   6277  S SD  A MET B 1 372 ? 44.427  -4.533  -17.364  0.46 29.45  ? 365  MET B SD  1 
ATOM   6278  S SD  B MET B 1 372 ? 42.950  -6.761  -18.872  0.54 25.39  ? 365  MET B SD  1 
ATOM   6279  C CE  A MET B 1 372 ? 42.846  -3.925  -16.792  0.46 28.41  ? 365  MET B CE  1 
ATOM   6280  C CE  B MET B 1 372 ? 43.842  -7.725  -17.654  0.54 24.57  ? 365  MET B CE  1 
ATOM   6281  N N   . LEU B 1 373 ? 41.239  -5.678  -21.355  1.00 23.96  ? 366  LEU B N   1 
ATOM   6282  C CA  . LEU B 1 373 ? 40.368  -6.866  -21.578  1.00 22.01  ? 366  LEU B CA  1 
ATOM   6283  C C   . LEU B 1 373 ? 40.316  -7.250  -23.056  1.00 21.42  ? 366  LEU B C   1 
ATOM   6284  O O   . LEU B 1 373 ? 40.402  -8.455  -23.352  1.00 20.91  ? 366  LEU B O   1 
ATOM   6285  C CB  . LEU B 1 373 ? 38.960  -6.553  -21.077  1.00 21.88  ? 366  LEU B CB  1 
ATOM   6286  C CG  . LEU B 1 373 ? 38.769  -6.666  -19.566  1.00 21.19  ? 366  LEU B CG  1 
ATOM   6287  C CD1 . LEU B 1 373 ? 37.335  -6.277  -19.228  1.00 21.63  ? 366  LEU B CD1 1 
ATOM   6288  C CD2 . LEU B 1 373 ? 39.100  -8.074  -19.061  1.00 20.13  ? 366  LEU B CD2 1 
ATOM   6289  N N   . LEU B 1 374 ? 40.169  -6.272  -23.949  1.00 20.50  ? 367  LEU B N   1 
ATOM   6290  C CA  . LEU B 1 374 ? 40.080  -6.514  -25.407  1.00 19.85  ? 367  LEU B CA  1 
ATOM   6291  C C   . LEU B 1 374 ? 41.398  -7.136  -25.875  1.00 20.81  ? 367  LEU B C   1 
ATOM   6292  O O   . LEU B 1 374 ? 41.333  -8.121  -26.646  1.00 20.84  ? 367  LEU B O   1 
ATOM   6293  C CB  . LEU B 1 374 ? 39.774  -5.198  -26.124  1.00 19.47  ? 367  LEU B CB  1 
ATOM   6294  C CG  . LEU B 1 374 ? 39.593  -5.313  -27.635  1.00 21.67  ? 367  LEU B CG  1 
ATOM   6295  C CD1 . LEU B 1 374 ? 38.577  -6.380  -28.013  1.00 21.41  ? 367  LEU B CD1 1 
ATOM   6296  C CD2 . LEU B 1 374 ? 39.234  -3.975  -28.230  1.00 23.17  ? 367  LEU B CD2 1 
ATOM   6297  N N   . ASP B 1 375 ? 42.546  -6.603  -25.422  1.00 20.80  ? 368  ASP B N   1 
ATOM   6298  C CA  . ASP B 1 375 ? 43.887  -7.143  -25.754  1.00 20.87  ? 368  ASP B CA  1 
ATOM   6299  C C   . ASP B 1 375 ? 43.890  -8.600  -25.313  1.00 20.82  ? 368  ASP B C   1 
ATOM   6300  O O   . ASP B 1 375 ? 44.262  -9.438  -26.107  1.00 23.03  ? 368  ASP B O   1 
ATOM   6301  C CB  . ASP B 1 375 ? 45.029  -6.356  -25.093  1.00 21.94  ? 368  ASP B CB  1 
ATOM   6302  C CG  . ASP B 1 375 ? 46.447  -6.921  -25.247  1.00 22.02  ? 368  ASP B CG  1 
ATOM   6303  O OD1 . ASP B 1 375 ? 46.946  -6.950  -26.391  1.00 22.91  ? 368  ASP B OD1 1 
ATOM   6304  O OD2 . ASP B 1 375 ? 47.069  -7.306  -24.216  1.00 21.44  ? 368  ASP B OD2 1 
ATOM   6305  N N   . GLY B 1 376 ? 43.456  -8.879  -24.089  1.00 20.79  ? 369  GLY B N   1 
ATOM   6306  C CA  . GLY B 1 376 ? 43.380  -10.251 -23.563  1.00 21.59  ? 369  GLY B CA  1 
ATOM   6307  C C   . GLY B 1 376 ? 42.589  -11.143 -24.488  1.00 22.45  ? 369  GLY B C   1 
ATOM   6308  O O   . GLY B 1 376 ? 43.073  -12.224 -24.797  1.00 23.70  ? 369  GLY B O   1 
ATOM   6309  N N   . PHE B 1 377 ? 41.419  -10.692 -24.931  1.00 23.86  ? 370  PHE B N   1 
ATOM   6310  C CA  . PHE B 1 377 ? 40.487  -11.505 -25.751  1.00 24.53  ? 370  PHE B CA  1 
ATOM   6311  C C   . PHE B 1 377 ? 41.065  -11.703 -27.146  1.00 25.69  ? 370  PHE B C   1 
ATOM   6312  O O   . PHE B 1 377 ? 41.038  -12.838 -27.643  1.00 27.38  ? 370  PHE B O   1 
ATOM   6313  C CB  . PHE B 1 377 ? 39.108  -10.859 -25.805  1.00 24.50  ? 370  PHE B CB  1 
ATOM   6314  C CG  . PHE B 1 377 ? 38.402  -10.842 -24.475  1.00 25.41  ? 370  PHE B CG  1 
ATOM   6315  C CD1 . PHE B 1 377 ? 38.408  -11.962 -23.653  1.00 24.27  ? 370  PHE B CD1 1 
ATOM   6316  C CD2 . PHE B 1 377 ? 37.688  -9.722  -24.067  1.00 25.86  ? 370  PHE B CD2 1 
ATOM   6317  C CE1 . PHE B 1 377 ? 37.741  -11.949 -22.440  1.00 24.21  ? 370  PHE B CE1 1 
ATOM   6318  C CE2 . PHE B 1 377 ? 37.036  -9.713  -22.845  1.00 24.46  ? 370  PHE B CE2 1 
ATOM   6319  C CZ  . PHE B 1 377 ? 37.061  -10.824 -22.038  1.00 23.95  ? 370  PHE B CZ  1 
ATOM   6320  N N   A ARG B 1 378 ? 41.556  -10.626 -27.763  0.48 24.75  ? 371  ARG B N   1 
ATOM   6321  N N   B ARG B 1 378 ? 41.553  -10.623 -27.766  0.52 26.19  ? 371  ARG B N   1 
ATOM   6322  C CA  A ARG B 1 378 ? 42.196  -10.662 -29.104  0.48 24.01  ? 371  ARG B CA  1 
ATOM   6323  C CA  B ARG B 1 378 ? 42.196  -10.659 -29.104  0.52 26.30  ? 371  ARG B CA  1 
ATOM   6324  C C   A ARG B 1 378 ? 43.327  -11.697 -29.077  0.48 24.58  ? 371  ARG B C   1 
ATOM   6325  C C   B ARG B 1 378 ? 43.323  -11.700 -29.076  0.52 25.93  ? 371  ARG B C   1 
ATOM   6326  O O   A ARG B 1 378 ? 43.476  -12.428 -30.066  0.48 25.05  ? 371  ARG B O   1 
ATOM   6327  O O   B ARG B 1 378 ? 43.472  -12.432 -30.068  0.52 26.33  ? 371  ARG B O   1 
ATOM   6328  C CB  A ARG B 1 378 ? 42.685  -9.269  -29.513  0.48 23.46  ? 371  ARG B CB  1 
ATOM   6329  C CB  B ARG B 1 378 ? 42.734  -9.276  -29.489  0.52 27.61  ? 371  ARG B CB  1 
ATOM   6330  C CG  A ARG B 1 378 ? 41.560  -8.389  -30.037  0.48 22.26  ? 371  ARG B CG  1 
ATOM   6331  C CG  B ARG B 1 378 ? 41.705  -8.295  -30.028  0.52 27.85  ? 371  ARG B CG  1 
ATOM   6332  C CD  A ARG B 1 378 ? 41.931  -7.128  -30.795  0.48 21.27  ? 371  ARG B CD  1 
ATOM   6333  C CD  B ARG B 1 378 ? 42.428  -7.228  -30.841  0.52 28.58  ? 371  ARG B CD  1 
ATOM   6334  N NE  A ARG B 1 378 ? 42.681  -7.324  -32.032  0.48 20.73  ? 371  ARG B NE  1 
ATOM   6335  N NE  B ARG B 1 378 ? 41.679  -6.022  -31.186  0.52 28.72  ? 371  ARG B NE  1 
ATOM   6336  C CZ  A ARG B 1 378 ? 42.175  -7.553  -33.236  0.48 18.83  ? 371  ARG B CZ  1 
ATOM   6337  C CZ  B ARG B 1 378 ? 41.877  -4.805  -30.666  0.52 29.32  ? 371  ARG B CZ  1 
ATOM   6338  N NH1 A ARG B 1 378 ? 40.871  -7.654  -33.417  0.48 18.90  ? 371  ARG B NH1 1 
ATOM   6339  N NH1 B ARG B 1 378 ? 42.794  -4.585  -29.732  0.52 28.88  ? 371  ARG B NH1 1 
ATOM   6340  N NH2 A ARG B 1 378 ? 42.994  -7.705  -34.253  0.48 17.79  ? 371  ARG B NH2 1 
ATOM   6341  N NH2 B ARG B 1 378 ? 41.143  -3.794  -31.093  0.52 29.24  ? 371  ARG B NH2 1 
ATOM   6342  N N   . GLN B 1 379 ? 44.077  -11.774 -27.975  1.00 24.67  ? 372  GLN B N   1 
ATOM   6343  C CA  . GLN B 1 379 ? 45.199  -12.731 -27.811  1.00 24.30  ? 372  GLN B CA  1 
ATOM   6344  C C   . GLN B 1 379 ? 44.638  -14.150 -27.750  1.00 24.76  ? 372  GLN B C   1 
ATOM   6345  O O   . GLN B 1 379 ? 45.176  -15.013 -28.446  1.00 23.64  ? 372  GLN B O   1 
ATOM   6346  C CB  . GLN B 1 379 ? 46.023  -12.401 -26.567  1.00 23.39  ? 372  GLN B CB  1 
ATOM   6347  C CG  . GLN B 1 379 ? 47.249  -13.289 -26.391  1.00 25.31  ? 372  GLN B CG  1 
ATOM   6348  C CD  . GLN B 1 379 ? 48.131  -13.387 -27.613  1.00 25.21  ? 372  GLN B CD  1 
ATOM   6349  O OE1 . GLN B 1 379 ? 48.248  -12.454 -28.407  1.00 26.18  ? 372  GLN B OE1 1 
ATOM   6350  N NE2 . GLN B 1 379 ? 48.748  -14.543 -27.777  1.00 25.23  ? 372  GLN B NE2 1 
ATOM   6351  N N   . LEU B 1 380 ? 43.577  -14.379 -26.973  1.00 24.92  ? 373  LEU B N   1 
ATOM   6352  C CA  . LEU B 1 380 ? 42.890  -15.702 -26.904  1.00 25.01  ? 373  LEU B CA  1 
ATOM   6353  C C   . LEU B 1 380 ? 42.317  -16.069 -28.278  1.00 25.35  ? 373  LEU B C   1 
ATOM   6354  O O   . LEU B 1 380 ? 42.264  -17.268 -28.591  1.00 24.81  ? 373  LEU B O   1 
ATOM   6355  C CB  . LEU B 1 380 ? 41.807  -15.658 -25.826  1.00 25.62  ? 373  LEU B CB  1 
ATOM   6356  C CG  . LEU B 1 380 ? 42.339  -15.628 -24.392  1.00 25.00  ? 373  LEU B CG  1 
ATOM   6357  C CD1 . LEU B 1 380 ? 41.217  -15.515 -23.377  1.00 25.91  ? 373  LEU B CD1 1 
ATOM   6358  C CD2 . LEU B 1 380 ? 43.150  -16.869 -24.111  1.00 24.74  ? 373  LEU B CD2 1 
ATOM   6359  N N   . ALA B 1 381 ? 41.934  -15.077 -29.075  1.00 25.55  ? 374  ALA B N   1 
ATOM   6360  C CA  . ALA B 1 381 ? 41.418  -15.280 -30.443  1.00 27.15  ? 374  ALA B CA  1 
ATOM   6361  C C   . ALA B 1 381 ? 42.550  -15.811 -31.320  1.00 26.64  ? 374  ALA B C   1 
ATOM   6362  O O   . ALA B 1 381 ? 42.319  -16.795 -32.047  1.00 25.16  ? 374  ALA B O   1 
ATOM   6363  C CB  . ALA B 1 381 ? 40.832  -14.000 -30.992  1.00 28.58  ? 374  ALA B CB  1 
ATOM   6364  N N   . ARG B 1 382 ? 43.722  -15.177 -31.233  1.00 28.72  ? 375  ARG B N   1 
ATOM   6365  C CA  . ARG B 1 382 ? 44.959  -15.615 -31.933  1.00 29.87  ? 375  ARG B CA  1 
ATOM   6366  C C   . ARG B 1 382 ? 45.255  -17.064 -31.559  1.00 28.89  ? 375  ARG B C   1 
ATOM   6367  O O   . ARG B 1 382 ? 45.605  -17.841 -32.451  1.00 31.24  ? 375  ARG B O   1 
ATOM   6368  C CB  . ARG B 1 382 ? 46.147  -14.703 -31.611  1.00 30.40  ? 375  ARG B CB  1 
ATOM   6369  C CG  . ARG B 1 382 ? 46.270  -13.578 -32.621  1.00 32.85  ? 375  ARG B CG  1 
ATOM   6370  C CD  . ARG B 1 382 ? 47.458  -12.664 -32.443  1.00 34.75  ? 375  ARG B CD  1 
ATOM   6371  N NE  . ARG B 1 382 ? 46.921  -11.308 -32.482  1.00 36.62  ? 375  ARG B NE  1 
ATOM   6372  C CZ  . ARG B 1 382 ? 46.713  -10.532 -31.414  1.00 38.30  ? 375  ARG B CZ  1 
ATOM   6373  N NH1 . ARG B 1 382 ? 47.044  -10.960 -30.193  1.00 38.66  ? 375  ARG B NH1 1 
ATOM   6374  N NH2 . ARG B 1 382 ? 46.197  -9.317  -31.586  1.00 37.19  ? 375  ARG B NH2 1 
ATOM   6375  N N   . GLU B 1 383 ? 45.064  -17.413 -30.298  1.00 28.56  ? 376  GLU B N   1 
ATOM   6376  C CA  . GLU B 1 383 ? 45.458  -18.730 -29.748  1.00 31.72  ? 376  GLU B CA  1 
ATOM   6377  C C   . GLU B 1 383 ? 44.411  -19.782 -30.088  1.00 32.49  ? 376  GLU B C   1 
ATOM   6378  O O   . GLU B 1 383 ? 44.805  -20.939 -30.209  1.00 32.22  ? 376  GLU B O   1 
ATOM   6379  C CB  . GLU B 1 383 ? 45.687  -18.594 -28.242  1.00 33.02  ? 376  GLU B CB  1 
ATOM   6380  C CG  . GLU B 1 383 ? 46.807  -17.610 -27.953  1.00 36.47  ? 376  GLU B CG  1 
ATOM   6381  C CD  . GLU B 1 383 ? 47.389  -17.661 -26.562  1.00 38.63  ? 376  GLU B CD  1 
ATOM   6382  O OE1 . GLU B 1 383 ? 47.309  -18.743 -25.964  1.00 44.41  ? 376  GLU B OE1 1 
ATOM   6383  O OE2 . GLU B 1 383 ? 47.886  -16.616 -26.074  1.00 38.91  ? 376  GLU B OE2 1 
ATOM   6384  N N   . TYR B 1 384 ? 43.138  -19.402 -30.245  1.00 33.58  ? 377  TYR B N   1 
ATOM   6385  C CA  . TYR B 1 384 ? 42.011  -20.353 -30.436  1.00 29.98  ? 377  TYR B CA  1 
ATOM   6386  C C   . TYR B 1 384 ? 41.199  -19.941 -31.647  1.00 30.07  ? 377  TYR B C   1 
ATOM   6387  O O   . TYR B 1 384 ? 40.032  -19.616 -31.538  1.00 35.77  ? 377  TYR B O   1 
ATOM   6388  C CB  . TYR B 1 384 ? 41.171  -20.437 -29.166  1.00 29.96  ? 377  TYR B CB  1 
ATOM   6389  C CG  . TYR B 1 384 ? 41.890  -21.017 -27.972  1.00 28.73  ? 377  TYR B CG  1 
ATOM   6390  C CD1 . TYR B 1 384 ? 41.931  -22.388 -27.758  1.00 28.58  ? 377  TYR B CD1 1 
ATOM   6391  C CD2 . TYR B 1 384 ? 42.517  -20.191 -27.049  1.00 27.55  ? 377  TYR B CD2 1 
ATOM   6392  C CE1 . TYR B 1 384 ? 42.575  -22.923 -26.654  1.00 29.06  ? 377  TYR B CE1 1 
ATOM   6393  C CE2 . TYR B 1 384 ? 43.160  -20.709 -25.940  1.00 26.67  ? 377  TYR B CE2 1 
ATOM   6394  C CZ  . TYR B 1 384 ? 43.201  -22.079 -25.752  1.00 27.81  ? 377  TYR B CZ  1 
ATOM   6395  O OH  . TYR B 1 384 ? 43.855  -22.612 -24.678  1.00 29.54  ? 377  TYR B OH  1 
ATOM   6396  N N   . PRO B 1 385 ? 41.801  -19.957 -32.848  1.00 28.99  ? 378  PRO B N   1 
ATOM   6397  C CA  . PRO B 1 385 ? 41.077  -19.671 -34.084  1.00 28.68  ? 378  PRO B CA  1 
ATOM   6398  C C   . PRO B 1 385 ? 40.137  -20.804 -34.511  1.00 28.95  ? 378  PRO B C   1 
ATOM   6399  O O   . PRO B 1 385 ? 39.279  -20.571 -35.342  1.00 29.59  ? 378  PRO B O   1 
ATOM   6400  C CB  . PRO B 1 385 ? 42.212  -19.538 -35.102  1.00 29.18  ? 378  PRO B CB  1 
ATOM   6401  C CG  . PRO B 1 385 ? 43.285  -20.461 -34.571  1.00 28.44  ? 378  PRO B CG  1 
ATOM   6402  C CD  . PRO B 1 385 ? 43.222  -20.266 -33.076  1.00 28.93  ? 378  PRO B CD  1 
ATOM   6403  N N   . ASP B 1 386 ? 40.339  -21.998 -33.946  1.00 29.24  ? 379  ASP B N   1 
ATOM   6404  C CA  . ASP B 1 386 ? 39.467  -23.192 -34.113  1.00 30.24  ? 379  ASP B CA  1 
ATOM   6405  C C   . ASP B 1 386 ? 38.103  -22.945 -33.441  1.00 30.46  ? 379  ASP B C   1 
ATOM   6406  O O   . ASP B 1 386 ? 37.119  -23.613 -33.828  1.00 28.34  ? 379  ASP B O   1 
ATOM   6407  C CB  . ASP B 1 386 ? 40.154  -24.435 -33.538  1.00 30.73  ? 379  ASP B CB  1 
ATOM   6408  C CG  . ASP B 1 386 ? 40.697  -24.245 -32.127  1.00 31.95  ? 379  ASP B CG  1 
ATOM   6409  O OD1 . ASP B 1 386 ? 41.259  -23.164 -31.842  1.00 30.08  ? 379  ASP B OD1 1 
ATOM   6410  O OD2 . ASP B 1 386 ? 40.564  -25.182 -31.315  1.00 36.41  ? 379  ASP B OD2 1 
ATOM   6411  N N   . LEU B 1 387 ? 38.051  -22.034 -32.464  1.00 30.52  ? 380  LEU B N   1 
ATOM   6412  C CA  . LEU B 1 387 ? 36.858  -21.752 -31.620  1.00 31.23  ? 380  LEU B CA  1 
ATOM   6413  C C   . LEU B 1 387 ? 36.375  -20.315 -31.821  1.00 29.85  ? 380  LEU B C   1 
ATOM   6414  O O   . LEU B 1 387 ? 35.157  -20.088 -31.879  1.00 29.61  ? 380  LEU B O   1 
ATOM   6415  C CB  . LEU B 1 387 ? 37.254  -21.991 -30.164  1.00 31.16  ? 380  LEU B CB  1 
ATOM   6416  C CG  . LEU B 1 387 ? 37.649  -23.434 -29.851  1.00 33.17  ? 380  LEU B CG  1 
ATOM   6417  C CD1 . LEU B 1 387 ? 37.986  -23.618 -28.380  1.00 35.24  ? 380  LEU B CD1 1 
ATOM   6418  C CD2 . LEU B 1 387 ? 36.546  -24.402 -30.260  1.00 35.56  ? 380  LEU B CD2 1 
ATOM   6419  N N   . VAL B 1 388 ? 37.299  -19.367 -31.926  1.00 29.29  ? 381  VAL B N   1 
ATOM   6420  C CA  . VAL B 1 388 ? 36.973  -17.913 -31.925  1.00 28.95  ? 381  VAL B CA  1 
ATOM   6421  C C   . VAL B 1 388 ? 37.219  -17.335 -33.309  1.00 29.62  ? 381  VAL B C   1 
ATOM   6422  O O   . VAL B 1 388 ? 38.317  -17.531 -33.828  1.00 31.96  ? 381  VAL B O   1 
ATOM   6423  C CB  . VAL B 1 388 ? 37.817  -17.181 -30.877  1.00 27.60  ? 381  VAL B CB  1 
ATOM   6424  C CG1 . VAL B 1 388 ? 37.549  -15.687 -30.898  1.00 26.75  ? 381  VAL B CG1 1 
ATOM   6425  C CG2 . VAL B 1 388 ? 37.599  -17.771 -29.495  1.00 28.54  ? 381  VAL B CG2 1 
ATOM   6426  N N   . GLN B 1 389 ? 36.239  -16.626 -33.858  1.00 32.73  ? 382  GLN B N   1 
ATOM   6427  C CA  . GLN B 1 389 ? 36.380  -15.884 -35.134  1.00 35.59  ? 382  GLN B CA  1 
ATOM   6428  C C   . GLN B 1 389 ? 37.162  -14.610 -34.814  1.00 31.88  ? 382  GLN B C   1 
ATOM   6429  O O   . GLN B 1 389 ? 38.245  -14.438 -35.391  1.00 32.25  ? 382  GLN B O   1 
ATOM   6430  C CB  . GLN B 1 389 ? 35.005  -15.645 -35.775  1.00 41.35  ? 382  GLN B CB  1 
ATOM   6431  C CG  . GLN B 1 389 ? 34.977  -14.921 -37.116  1.00 47.25  ? 382  GLN B CG  1 
ATOM   6432  C CD  . GLN B 1 389 ? 35.660  -15.681 -38.229  1.00 54.49  ? 382  GLN B CD  1 
ATOM   6433  O OE1 . GLN B 1 389 ? 35.579  -16.908 -38.348  1.00 58.88  ? 382  GLN B OE1 1 
ATOM   6434  N NE2 . GLN B 1 389 ? 36.372  -14.938 -39.058  1.00 58.75  ? 382  GLN B NE2 1 
ATOM   6435  N N   . GLU B 1 390 ? 36.671  -13.793 -33.881  1.00 27.01  ? 383  GLU B N   1 
ATOM   6436  C CA  . GLU B 1 390 ? 37.303  -12.488 -33.574  1.00 25.61  ? 383  GLU B CA  1 
ATOM   6437  C C   . GLU B 1 390 ? 36.753  -11.945 -32.252  1.00 23.87  ? 383  GLU B C   1 
ATOM   6438  O O   . GLU B 1 390 ? 35.695  -12.400 -31.815  1.00 23.96  ? 383  GLU B O   1 
ATOM   6439  C CB  . GLU B 1 390 ? 37.115  -11.564 -34.783  1.00 25.80  ? 383  GLU B CB  1 
ATOM   6440  C CG  . GLU B 1 390 ? 36.299  -10.306 -34.532  1.00 27.42  ? 383  GLU B CG  1 
ATOM   6441  C CD  . GLU B 1 390 ? 36.254  -9.345  -35.714  1.00 27.06  ? 383  GLU B CD  1 
ATOM   6442  O OE1 . GLU B 1 390 ? 37.331  -8.927  -36.155  1.00 28.18  ? 383  GLU B OE1 1 
ATOM   6443  O OE2 . GLU B 1 390 ? 35.168  -8.998  -36.182  1.00 25.08  ? 383  GLU B OE2 1 
ATOM   6444  N N   . ALA B 1 391 ? 37.487  -11.027 -31.622  1.00 22.52  ? 384  ALA B N   1 
ATOM   6445  C CA  . ALA B 1 391 ? 37.022  -10.201 -30.488  1.00 21.60  ? 384  ALA B CA  1 
ATOM   6446  C C   . ALA B 1 391 ? 37.097  -8.727  -30.892  1.00 21.16  ? 384  ALA B C   1 
ATOM   6447  O O   . ALA B 1 391 ? 38.086  -8.332  -31.506  1.00 19.53  ? 384  ALA B O   1 
ATOM   6448  C CB  . ALA B 1 391 ? 37.830  -10.497 -29.256  1.00 21.00  ? 384  ALA B CB  1 
ATOM   6449  N N   . ARG B 1 392 ? 36.058  -7.961  -30.567  1.00 21.97  ? 385  ARG B N   1 
ATOM   6450  C CA  . ARG B 1 392 ? 35.920  -6.515  -30.873  1.00 22.53  ? 385  ARG B CA  1 
ATOM   6451  C C   . ARG B 1 392 ? 35.525  -5.789  -29.591  1.00 20.95  ? 385  ARG B C   1 
ATOM   6452  O O   . ARG B 1 392 ? 35.012  -6.464  -28.666  1.00 20.01  ? 385  ARG B O   1 
ATOM   6453  C CB  . ARG B 1 392 ? 34.774  -6.198  -31.840  1.00 25.07  ? 385  ARG B CB  1 
ATOM   6454  C CG  . ARG B 1 392 ? 34.429  -7.278  -32.858  1.00 27.76  ? 385  ARG B CG  1 
ATOM   6455  C CD  . ARG B 1 392 ? 33.311  -6.848  -33.799  1.00 28.35  ? 385  ARG B CD  1 
ATOM   6456  N NE  . ARG B 1 392 ? 32.065  -7.570  -33.576  1.00 29.97  ? 385  ARG B NE  1 
ATOM   6457  C CZ  . ARG B 1 392 ? 31.866  -8.850  -33.911  1.00 30.52  ? 385  ARG B CZ  1 
ATOM   6458  N NH1 . ARG B 1 392 ? 32.834  -9.559  -34.482  1.00 29.04  ? 385  ARG B NH1 1 
ATOM   6459  N NH2 . ARG B 1 392 ? 30.685  -9.410  -33.680  1.00 30.22  ? 385  ARG B NH2 1 
ATOM   6460  N N   . GLY B 1 393 ? 35.656  -4.461  -29.591  1.00 20.11  ? 386  GLY B N   1 
ATOM   6461  C CA  . GLY B 1 393 ? 35.130  -3.612  -28.511  1.00 20.28  ? 386  GLY B CA  1 
ATOM   6462  C C   . GLY B 1 393 ? 35.539  -2.161  -28.628  1.00 20.53  ? 386  GLY B C   1 
ATOM   6463  O O   . GLY B 1 393 ? 36.296  -1.812  -29.520  1.00 21.12  ? 386  GLY B O   1 
ATOM   6464  N N   . LYS B 1 394 ? 35.020  -1.359  -27.719  1.00 22.29  ? 387  LYS B N   1 
ATOM   6465  C CA  . LYS B 1 394 ? 35.395  0.047   -27.476  1.00 24.95  ? 387  LYS B CA  1 
ATOM   6466  C C   . LYS B 1 394 ? 35.056  0.312   -26.007  1.00 25.49  ? 387  LYS B C   1 
ATOM   6467  O O   . LYS B 1 394 ? 33.891  0.112   -25.612  1.00 27.46  ? 387  LYS B O   1 
ATOM   6468  C CB  . LYS B 1 394 ? 34.636  0.947   -28.452  1.00 26.94  ? 387  LYS B CB  1 
ATOM   6469  C CG  . LYS B 1 394 ? 34.721  2.443   -28.188  1.00 29.91  ? 387  LYS B CG  1 
ATOM   6470  C CD  . LYS B 1 394 ? 36.014  3.084   -28.624  1.00 32.77  ? 387  LYS B CD  1 
ATOM   6471  C CE  . LYS B 1 394 ? 35.801  4.336   -29.448  1.00 36.04  ? 387  LYS B CE  1 
ATOM   6472  N NZ  . LYS B 1 394 ? 37.080  4.768   -30.058  1.00 38.26  ? 387  LYS B NZ  1 
ATOM   6473  N N   . GLY B 1 395 ? 36.038  0.704   -25.206  1.00 23.63  ? 388  GLY B N   1 
ATOM   6474  C CA  . GLY B 1 395 ? 35.855  0.752   -23.747  1.00 23.20  ? 388  GLY B CA  1 
ATOM   6475  C C   . GLY B 1 395 ? 35.376  -0.595  -23.243  1.00 22.68  ? 388  GLY B C   1 
ATOM   6476  O O   . GLY B 1 395 ? 35.910  -1.622  -23.676  1.00 22.68  ? 388  GLY B O   1 
ATOM   6477  N N   . MET B 1 396 ? 34.358  -0.601  -22.393  1.00 24.55  ? 389  MET B N   1 
ATOM   6478  C CA  . MET B 1 396 ? 33.869  -1.823  -21.710  1.00 26.14  ? 389  MET B CA  1 
ATOM   6479  C C   . MET B 1 396 ? 32.674  -2.404  -22.466  1.00 25.35  ? 389  MET B C   1 
ATOM   6480  O O   . MET B 1 396 ? 31.929  -3.209  -21.878  1.00 24.25  ? 389  MET B O   1 
ATOM   6481  C CB  . MET B 1 396 ? 33.482  -1.494  -20.270  1.00 28.15  ? 389  MET B CB  1 
ATOM   6482  C CG  . MET B 1 396 ? 34.696  -1.153  -19.423  1.00 28.49  ? 389  MET B CG  1 
ATOM   6483  S SD  . MET B 1 396 ? 35.729  -2.608  -19.090  1.00 29.07  ? 389  MET B SD  1 
ATOM   6484  C CE  . MET B 1 396 ? 35.237  -3.017  -17.422  1.00 24.98  ? 389  MET B CE  1 
ATOM   6485  N N   . LEU B 1 397 ? 32.513  -2.012  -23.726  1.00 23.96  ? 390  LEU B N   1 
ATOM   6486  C CA  . LEU B 1 397 ? 31.526  -2.624  -24.639  1.00 23.18  ? 390  LEU B CA  1 
ATOM   6487  C C   . LEU B 1 397 ? 32.285  -3.544  -25.584  1.00 22.85  ? 390  LEU B C   1 
ATOM   6488  O O   . LEU B 1 397 ? 32.956  -3.032  -26.494  1.00 21.78  ? 390  LEU B O   1 
ATOM   6489  C CB  . LEU B 1 397 ? 30.776  -1.526  -25.390  1.00 23.98  ? 390  LEU B CB  1 
ATOM   6490  C CG  . LEU B 1 397 ? 29.640  -2.018  -26.282  1.00 26.77  ? 390  LEU B CG  1 
ATOM   6491  C CD1 . LEU B 1 397 ? 28.608  -2.838  -25.510  1.00 27.53  ? 390  LEU B CD1 1 
ATOM   6492  C CD2 . LEU B 1 397 ? 28.987  -0.838  -26.986  1.00 29.26  ? 390  LEU B CD2 1 
ATOM   6493  N N   . MET B 1 398 ? 32.199  -4.848  -25.342  1.00 22.78  ? 391  MET B N   1 
ATOM   6494  C CA  . MET B 1 398 ? 33.036  -5.855  -26.031  1.00 23.21  ? 391  MET B CA  1 
ATOM   6495  C C   . MET B 1 398 ? 32.197  -7.072  -26.392  1.00 23.03  ? 391  MET B C   1 
ATOM   6496  O O   . MET B 1 398 ? 31.152  -7.297  -25.768  1.00 25.20  ? 391  MET B O   1 
ATOM   6497  C CB  . MET B 1 398 ? 34.186  -6.295  -25.124  1.00 24.15  ? 391  MET B CB  1 
ATOM   6498  C CG  . MET B 1 398 ? 35.270  -5.256  -24.985  1.00 25.68  ? 391  MET B CG  1 
ATOM   6499  S SD  . MET B 1 398 ? 36.399  -5.644  -23.637  1.00 25.97  ? 391  MET B SD  1 
ATOM   6500  C CE  . MET B 1 398 ? 35.284  -5.483  -22.247  1.00 22.61  ? 391  MET B CE  1 
ATOM   6501  N N   . ALA B 1 399 ? 32.682  -7.827  -27.364  1.00 25.06  ? 392  ALA B N   1 
ATOM   6502  C CA  . ALA B 1 399 ? 32.083  -9.086  -27.852  1.00 25.37  ? 392  ALA B CA  1 
ATOM   6503  C C   . ALA B 1 399 ? 33.195  -10.020 -28.326  1.00 25.33  ? 392  ALA B C   1 
ATOM   6504  O O   . ALA B 1 399 ? 34.213  -9.533  -28.860  1.00 23.00  ? 392  ALA B O   1 
ATOM   6505  C CB  . ALA B 1 399 ? 31.095  -8.823  -28.971  1.00 24.24  ? 392  ALA B CB  1 
ATOM   6506  N N   . ILE B 1 400 ? 32.968  -11.313 -28.120  1.00 26.06  ? 393  ILE B N   1 
ATOM   6507  C CA  . ILE B 1 400 ? 33.726  -12.423 -28.751  1.00 27.97  ? 393  ILE B CA  1 
ATOM   6508  C C   . ILE B 1 400 ? 32.779  -13.137 -29.704  1.00 28.70  ? 393  ILE B C   1 
ATOM   6509  O O   . ILE B 1 400 ? 31.776  -13.695 -29.217  1.00 28.69  ? 393  ILE B O   1 
ATOM   6510  C CB  . ILE B 1 400 ? 34.258  -13.381 -27.676  1.00 31.36  ? 393  ILE B CB  1 
ATOM   6511  C CG1 . ILE B 1 400 ? 35.107  -12.638 -26.640  1.00 33.32  ? 393  ILE B CG1 1 
ATOM   6512  C CG2 . ILE B 1 400 ? 35.015  -14.538 -28.310  1.00 29.29  ? 393  ILE B CG2 1 
ATOM   6513  C CD1 . ILE B 1 400 ? 35.281  -13.399 -25.357  1.00 36.05  ? 393  ILE B CD1 1 
ATOM   6514  N N   . GLU B 1 401 ? 33.086  -13.103 -31.004  1.00 28.05  ? 394  GLU B N   1 
ATOM   6515  C CA  . GLU B 1 401 ? 32.373  -13.896 -32.039  1.00 29.27  ? 394  GLU B CA  1 
ATOM   6516  C C   . GLU B 1 401 ? 33.042  -15.270 -32.137  1.00 29.20  ? 394  GLU B C   1 
ATOM   6517  O O   . GLU B 1 401 ? 34.251  -15.315 -32.420  1.00 33.93  ? 394  GLU B O   1 
ATOM   6518  C CB  . GLU B 1 401 ? 32.400  -13.159 -33.370  1.00 28.88  ? 394  GLU B CB  1 
ATOM   6519  C CG  . GLU B 1 401 ? 31.548  -13.822 -34.423  1.00 33.20  ? 394  GLU B CG  1 
ATOM   6520  C CD  . GLU B 1 401 ? 31.607  -13.154 -35.788  1.00 36.87  ? 394  GLU B CD  1 
ATOM   6521  O OE1 . GLU B 1 401 ? 32.267  -12.116 -35.925  1.00 43.06  ? 394  GLU B OE1 1 
ATOM   6522  O OE2 . GLU B 1 401 ? 31.014  -13.707 -36.729  1.00 40.24  ? 394  GLU B OE2 1 
ATOM   6523  N N   . PHE B 1 402 ? 32.300  -16.350 -31.899  1.00 26.35  ? 395  PHE B N   1 
ATOM   6524  C CA  . PHE B 1 402 ? 32.802  -17.739 -32.053  1.00 26.22  ? 395  PHE B CA  1 
ATOM   6525  C C   . PHE B 1 402 ? 32.526  -18.224 -33.478  1.00 27.64  ? 395  PHE B C   1 
ATOM   6526  O O   . PHE B 1 402 ? 31.836  -17.524 -34.242  1.00 25.65  ? 395  PHE B O   1 
ATOM   6527  C CB  . PHE B 1 402 ? 32.213  -18.633 -30.977  1.00 24.91  ? 395  PHE B CB  1 
ATOM   6528  C CG  . PHE B 1 402 ? 32.639  -18.173 -29.612  1.00 27.03  ? 395  PHE B CG  1 
ATOM   6529  C CD1 . PHE B 1 402 ? 32.006  -17.101 -28.996  1.00 26.67  ? 395  PHE B CD1 1 
ATOM   6530  C CD2 . PHE B 1 402 ? 33.736  -18.744 -28.990  1.00 27.70  ? 395  PHE B CD2 1 
ATOM   6531  C CE1 . PHE B 1 402 ? 32.429  -16.641 -27.761  1.00 27.36  ? 395  PHE B CE1 1 
ATOM   6532  C CE2 . PHE B 1 402 ? 34.171  -18.277 -27.758  1.00 28.48  ? 395  PHE B CE2 1 
ATOM   6533  C CZ  . PHE B 1 402 ? 33.508  -17.239 -27.141  1.00 28.86  ? 395  PHE B CZ  1 
ATOM   6534  N N   . VAL B 1 403 ? 33.104  -19.372 -33.824  1.00 29.69  ? 396  VAL B N   1 
ATOM   6535  C CA  . VAL B 1 403 ? 33.071  -19.940 -35.199  1.00 34.48  ? 396  VAL B CA  1 
ATOM   6536  C C   . VAL B 1 403 ? 31.620  -20.279 -35.555  1.00 37.03  ? 396  VAL B C   1 
ATOM   6537  O O   . VAL B 1 403 ? 31.215  -20.003 -36.691  1.00 35.65  ? 396  VAL B O   1 
ATOM   6538  C CB  . VAL B 1 403 ? 34.007  -21.161 -35.297  1.00 34.05  ? 396  VAL B CB  1 
ATOM   6539  C CG1 . VAL B 1 403 ? 33.696  -22.046 -36.499  1.00 34.87  ? 396  VAL B CG1 1 
ATOM   6540  C CG2 . VAL B 1 403 ? 35.462  -20.734 -35.291  1.00 30.60  ? 396  VAL B CG2 1 
ATOM   6541  N N   . ASP B 1 404 ? 30.873  -20.852 -34.607  1.00 42.37  ? 397  ASP B N   1 
ATOM   6542  C CA  . ASP B 1 404 ? 29.447  -21.233 -34.785  1.00 48.35  ? 397  ASP B CA  1 
ATOM   6543  C C   . ASP B 1 404 ? 28.697  -20.999 -33.469  1.00 47.40  ? 397  ASP B C   1 
ATOM   6544  O O   . ASP B 1 404 ? 29.359  -20.772 -32.429  1.00 43.54  ? 397  ASP B O   1 
ATOM   6545  C CB  . ASP B 1 404 ? 29.321  -22.667 -35.312  1.00 52.88  ? 397  ASP B CB  1 
ATOM   6546  C CG  . ASP B 1 404 ? 29.678  -23.753 -34.313  1.00 53.72  ? 397  ASP B CG  1 
ATOM   6547  O OD1 . ASP B 1 404 ? 29.264  -23.637 -33.152  1.00 54.81  ? 397  ASP B OD1 1 
ATOM   6548  O OD2 . ASP B 1 404 ? 30.360  -24.717 -34.713  1.00 60.77  ? 397  ASP B OD2 1 
ATOM   6549  N N   . ASN B 1 405 ? 27.366  -21.080 -33.514  1.00 49.88  ? 398  ASN B N   1 
ATOM   6550  C CA  . ASN B 1 405 ? 26.482  -20.697 -32.384  1.00 51.95  ? 398  ASN B CA  1 
ATOM   6551  C C   . ASN B 1 405 ? 26.735  -21.625 -31.197  1.00 44.67  ? 398  ASN B C   1 
ATOM   6552  O O   . ASN B 1 405 ? 26.853  -21.101 -30.085  1.00 38.94  ? 398  ASN B O   1 
ATOM   6553  C CB  . ASN B 1 405 ? 25.001  -20.681 -32.769  1.00 63.24  ? 398  ASN B CB  1 
ATOM   6554  C CG  . ASN B 1 405 ? 24.218  -19.618 -32.023  1.00 81.11  ? 398  ASN B CG  1 
ATOM   6555  O OD1 . ASN B 1 405 ? 24.736  -18.941 -31.127  1.00 92.45  ? 398  ASN B OD1 1 
ATOM   6556  N ND2 . ASN B 1 405 ? 22.960  -19.449 -32.393  1.00 92.30  ? 398  ASN B ND2 1 
ATOM   6557  N N   . GLU B 1 406 ? 26.827  -22.937 -31.435  1.00 44.08  ? 399  GLU B N   1 
ATOM   6558  C CA  . GLU B 1 406 ? 26.918  -23.978 -30.379  1.00 46.13  ? 399  GLU B CA  1 
ATOM   6559  C C   . GLU B 1 406 ? 28.209  -23.797 -29.583  1.00 42.79  ? 399  GLU B C   1 
ATOM   6560  O O   . GLU B 1 406 ? 28.190  -24.105 -28.380  1.00 51.08  ? 399  GLU B O   1 
ATOM   6561  C CB  . GLU B 1 406 ? 26.871  -25.383 -30.982  1.00 54.27  ? 399  GLU B CB  1 
ATOM   6562  C CG  . GLU B 1 406 ? 26.953  -26.511 -29.973  1.00 65.95  ? 399  GLU B CG  1 
ATOM   6563  C CD  . GLU B 1 406 ? 27.758  -27.733 -30.413  1.00 80.49  ? 399  GLU B CD  1 
ATOM   6564  O OE1 . GLU B 1 406 ? 27.745  -28.055 -31.624  1.00 83.85  ? 399  GLU B OE1 1 
ATOM   6565  O OE2 . GLU B 1 406 ? 28.428  -28.343 -29.543  1.00 85.99  ? 399  GLU B OE2 1 
ATOM   6566  N N   . ILE B 1 407 ? 29.282  -23.323 -30.219  1.00 39.10  ? 400  ILE B N   1 
ATOM   6567  C CA  . ILE B 1 407 ? 30.592  -23.023 -29.558  1.00 37.06  ? 400  ILE B CA  1 
ATOM   6568  C C   . ILE B 1 407 ? 30.417  -21.836 -28.600  1.00 35.15  ? 400  ILE B C   1 
ATOM   6569  O O   . ILE B 1 407 ? 30.896  -21.946 -27.464  1.00 30.28  ? 400  ILE B O   1 
ATOM   6570  C CB  . ILE B 1 407 ? 31.701  -22.799 -30.606  1.00 34.03  ? 400  ILE B CB  1 
ATOM   6571  C CG1 . ILE B 1 407 ? 32.064  -24.109 -31.314  1.00 31.01  ? 400  ILE B CG1 1 
ATOM   6572  C CG2 . ILE B 1 407 ? 32.913  -22.148 -29.958  1.00 34.79  ? 400  ILE B CG2 1 
ATOM   6573  C CD1 . ILE B 1 407 ? 32.910  -23.924 -32.544  1.00 31.42  ? 400  ILE B CD1 1 
ATOM   6574  N N   . GLY B 1 408 ? 29.740  -20.766 -29.044  1.00 36.11  ? 401  GLY B N   1 
ATOM   6575  C CA  . GLY B 1 408 ? 29.366  -19.588 -28.231  1.00 35.00  ? 401  GLY B CA  1 
ATOM   6576  C C   . GLY B 1 408 ? 28.672  -19.998 -26.951  1.00 38.11  ? 401  GLY B C   1 
ATOM   6577  O O   . GLY B 1 408 ? 29.007  -19.460 -25.884  1.00 39.21  ? 401  GLY B O   1 
ATOM   6578  N N   . TYR B 1 409 ? 27.747  -20.950 -27.051  1.00 42.54  ? 402  TYR B N   1 
ATOM   6579  C CA  . TYR B 1 409 ? 26.938  -21.462 -25.917  1.00 44.66  ? 402  TYR B CA  1 
ATOM   6580  C C   . TYR B 1 409 ? 27.849  -22.281 -25.007  1.00 39.42  ? 402  TYR B C   1 
ATOM   6581  O O   . TYR B 1 409 ? 27.691  -22.189 -23.798  1.00 34.49  ? 402  TYR B O   1 
ATOM   6582  C CB  . TYR B 1 409 ? 25.743  -22.299 -26.387  1.00 52.81  ? 402  TYR B CB  1 
ATOM   6583  C CG  . TYR B 1 409 ? 24.795  -21.636 -27.363  1.00 64.74  ? 402  TYR B CG  1 
ATOM   6584  C CD1 . TYR B 1 409 ? 24.527  -20.273 -27.317  1.00 70.69  ? 402  TYR B CD1 1 
ATOM   6585  C CD2 . TYR B 1 409 ? 24.126  -22.395 -28.318  1.00 70.72  ? 402  TYR B CD2 1 
ATOM   6586  C CE1 . TYR B 1 409 ? 23.640  -19.679 -28.201  1.00 78.66  ? 402  TYR B CE1 1 
ATOM   6587  C CE2 . TYR B 1 409 ? 23.242  -21.815 -29.214  1.00 78.05  ? 402  TYR B CE2 1 
ATOM   6588  C CZ  . TYR B 1 409 ? 22.992  -20.452 -29.153  1.00 83.30  ? 402  TYR B CZ  1 
ATOM   6589  O OH  . TYR B 1 409 ? 22.113  -19.859 -30.016  1.00 81.42  ? 402  TYR B OH  1 
ATOM   6590  N N   . ASN B 1 410 ? 28.766  -23.067 -25.564  1.00 37.90  ? 403  ASN B N   1 
ATOM   6591  C CA  . ASN B 1 410 ? 29.702  -23.897 -24.761  1.00 40.33  ? 403  ASN B CA  1 
ATOM   6592  C C   . ASN B 1 410 ? 30.600  -22.990 -23.920  1.00 33.85  ? 403  ASN B C   1 
ATOM   6593  O O   . ASN B 1 410 ? 30.907  -23.373 -22.770  1.00 32.98  ? 403  ASN B O   1 
ATOM   6594  C CB  . ASN B 1 410 ? 30.539  -24.832 -25.632  1.00 46.76  ? 403  ASN B CB  1 
ATOM   6595  C CG  . ASN B 1 410 ? 29.704  -25.971 -26.160  1.00 52.79  ? 403  ASN B CG  1 
ATOM   6596  O OD1 . ASN B 1 410 ? 28.866  -26.506 -25.440  1.00 58.14  ? 403  ASN B OD1 1 
ATOM   6597  N ND2 . ASN B 1 410 ? 29.901  -26.326 -27.415  1.00 55.14  ? 403  ASN B ND2 1 
ATOM   6598  N N   . PHE B 1 411 ? 30.963  -21.827 -24.464  1.00 28.46  ? 404  PHE B N   1 
ATOM   6599  C CA  . PHE B 1 411 ? 31.821  -20.826 -23.792  1.00 28.07  ? 404  PHE B CA  1 
ATOM   6600  C C   . PHE B 1 411 ? 31.055  -20.190 -22.636  1.00 27.50  ? 404  PHE B C   1 
ATOM   6601  O O   . PHE B 1 411 ? 31.585  -20.154 -21.530  1.00 28.66  ? 404  PHE B O   1 
ATOM   6602  C CB  . PHE B 1 411 ? 32.270  -19.755 -24.776  1.00 27.21  ? 404  PHE B CB  1 
ATOM   6603  C CG  . PHE B 1 411 ? 33.135  -18.687 -24.165  1.00 24.59  ? 404  PHE B CG  1 
ATOM   6604  C CD1 . PHE B 1 411 ? 34.481  -18.916 -23.974  1.00 23.81  ? 404  PHE B CD1 1 
ATOM   6605  C CD2 . PHE B 1 411 ? 32.607  -17.457 -23.811  1.00 22.46  ? 404  PHE B CD2 1 
ATOM   6606  C CE1 . PHE B 1 411 ? 35.291  -17.924 -23.448  1.00 23.68  ? 404  PHE B CE1 1 
ATOM   6607  C CE2 . PHE B 1 411 ? 33.415  -16.467 -23.292  1.00 21.91  ? 404  PHE B CE2 1 
ATOM   6608  C CZ  . PHE B 1 411 ? 34.756  -16.703 -23.107  1.00 23.05  ? 404  PHE B CZ  1 
ATOM   6609  N N   . ALA B 1 412 ? 29.846  -19.693 -22.890  1.00 26.75  ? 405  ALA B N   1 
ATOM   6610  C CA  . ALA B 1 412 ? 28.957  -19.124 -21.851  1.00 24.82  ? 405  ALA B CA  1 
ATOM   6611  C C   . ALA B 1 412 ? 28.856  -20.108 -20.683  1.00 25.40  ? 405  ALA B C   1 
ATOM   6612  O O   . ALA B 1 412 ? 28.968  -19.627 -19.550  1.00 24.02  ? 405  ALA B O   1 
ATOM   6613  C CB  . ALA B 1 412 ? 27.600  -18.791 -22.436  1.00 25.01  ? 405  ALA B CB  1 
ATOM   6614  N N   . SER B 1 413 ? 28.687  -21.416 -20.949  1.00 28.10  ? 406  SER B N   1 
ATOM   6615  C CA  . SER B 1 413 ? 28.512  -22.493 -19.924  1.00 31.96  ? 406  SER B CA  1 
ATOM   6616  C C   . SER B 1 413 ? 29.802  -22.673 -19.155  1.00 33.76  ? 406  SER B C   1 
ATOM   6617  O O   . SER B 1 413 ? 29.728  -22.699 -17.935  1.00 34.89  ? 406  SER B O   1 
ATOM   6618  C CB  . SER B 1 413 ? 28.128  -23.827 -20.488  1.00 33.74  ? 406  SER B CB  1 
ATOM   6619  O OG  . SER B 1 413 ? 27.206  -23.664 -21.545  1.00 44.90  ? 406  SER B OG  1 
ATOM   6620  N N   . GLU B 1 414 ? 30.920  -22.833 -19.870  1.00 36.88  ? 407  GLU B N   1 
ATOM   6621  C CA  . GLU B 1 414 ? 32.262  -23.032 -19.270  1.00 39.25  ? 407  GLU B CA  1 
ATOM   6622  C C   . GLU B 1 414 ? 32.551  -21.857 -18.337  1.00 36.53  ? 407  GLU B C   1 
ATOM   6623  O O   . GLU B 1 414 ? 32.955  -22.119 -17.197  1.00 40.46  ? 407  GLU B O   1 
ATOM   6624  C CB  . GLU B 1 414 ? 33.322  -23.203 -20.364  1.00 45.89  ? 407  GLU B CB  1 
ATOM   6625  C CG  . GLU B 1 414 ? 33.481  -24.640 -20.820  1.00 50.85  ? 407  GLU B CG  1 
ATOM   6626  C CD  . GLU B 1 414 ? 33.788  -25.605 -19.678  1.00 59.47  ? 407  GLU B CD  1 
ATOM   6627  O OE1 . GLU B 1 414 ? 34.535  -25.234 -18.734  1.00 62.06  ? 407  GLU B OE1 1 
ATOM   6628  O OE2 . GLU B 1 414 ? 33.254  -26.729 -19.717  1.00 71.47  ? 407  GLU B OE2 1 
ATOM   6629  N N   . MET B 1 415 ? 32.304  -20.623 -18.791  1.00 33.38  ? 408  MET B N   1 
ATOM   6630  C CA  . MET B 1 415 ? 32.506  -19.390 -17.982  1.00 33.53  ? 408  MET B CA  1 
ATOM   6631  C C   . MET B 1 415 ? 31.621  -19.414 -16.733  1.00 32.38  ? 408  MET B C   1 
ATOM   6632  O O   . MET B 1 415 ? 32.105  -19.081 -15.644  1.00 33.72  ? 408  MET B O   1 
ATOM   6633  C CB  . MET B 1 415 ? 32.182  -18.144 -18.808  1.00 32.74  ? 408  MET B CB  1 
ATOM   6634  C CG  . MET B 1 415 ? 33.237  -17.861 -19.844  1.00 32.51  ? 408  MET B CG  1 
ATOM   6635  S SD  . MET B 1 415 ? 34.844  -17.497 -19.127  1.00 31.20  ? 408  MET B SD  1 
ATOM   6636  C CE  . MET B 1 415 ? 34.742  -15.706 -19.058  1.00 31.41  ? 408  MET B CE  1 
ATOM   6637  N N   . PHE B 1 416 ? 30.362  -19.795 -16.883  1.00 31.07  ? 409  PHE B N   1 
ATOM   6638  C CA  . PHE B 1 416 ? 29.391  -19.893 -15.765  1.00 32.74  ? 409  PHE B CA  1 
ATOM   6639  C C   . PHE B 1 416 ? 29.868  -20.965 -14.780  1.00 33.13  ? 409  PHE B C   1 
ATOM   6640  O O   . PHE B 1 416 ? 29.757  -20.739 -13.568  1.00 34.77  ? 409  PHE B O   1 
ATOM   6641  C CB  . PHE B 1 416 ? 28.000  -20.199 -16.326  1.00 32.10  ? 409  PHE B CB  1 
ATOM   6642  C CG  . PHE B 1 416 ? 26.879  -20.057 -15.340  1.00 30.44  ? 409  PHE B CG  1 
ATOM   6643  C CD1 . PHE B 1 416 ? 26.246  -18.839 -15.169  1.00 30.69  ? 409  PHE B CD1 1 
ATOM   6644  C CD2 . PHE B 1 416 ? 26.459  -21.147 -14.596  1.00 31.56  ? 409  PHE B CD2 1 
ATOM   6645  C CE1 . PHE B 1 416 ? 25.219  -18.711 -14.254  1.00 29.64  ? 409  PHE B CE1 1 
ATOM   6646  C CE2 . PHE B 1 416 ? 25.442  -21.013 -13.671  1.00 32.26  ? 409  PHE B CE2 1 
ATOM   6647  C CZ  . PHE B 1 416 ? 24.823  -19.795 -13.508  1.00 30.56  ? 409  PHE B CZ  1 
ATOM   6648  N N   . ARG B 1 417 ? 30.403  -22.080 -15.285  1.00 38.50  ? 410  ARG B N   1 
ATOM   6649  C CA  . ARG B 1 417 ? 30.929  -23.177 -14.431  1.00 46.96  ? 410  ARG B CA  1 
ATOM   6650  C C   . ARG B 1 417 ? 32.028  -22.595 -13.544  1.00 41.30  ? 410  ARG B C   1 
ATOM   6651  O O   . ARG B 1 417 ? 32.139  -23.032 -12.385  1.00 44.34  ? 410  ARG B O   1 
ATOM   6652  C CB  . ARG B 1 417 ? 31.392  -24.392 -15.243  1.00 56.80  ? 410  ARG B CB  1 
ATOM   6653  C CG  . ARG B 1 417 ? 30.583  -25.639 -14.887  1.00 67.60  ? 410  ARG B CG  1 
ATOM   6654  C CD  . ARG B 1 417 ? 30.913  -26.946 -15.585  1.00 78.11  ? 410  ARG B CD  1 
ATOM   6655  N NE  . ARG B 1 417 ? 31.039  -26.866 -17.039  1.00 90.76  ? 410  ARG B NE  1 
ATOM   6656  C CZ  . ARG B 1 417 ? 30.057  -26.561 -17.903  1.00 101.01 ? 410  ARG B CZ  1 
ATOM   6657  N NH1 . ARG B 1 417 ? 28.838  -26.249 -17.486  1.00 102.86 ? 410  ARG B NH1 1 
ATOM   6658  N NH2 . ARG B 1 417 ? 30.311  -26.536 -19.203  1.00 95.65  ? 410  ARG B NH2 1 
ATOM   6659  N N   . GLN B 1 418 ? 32.745  -21.595 -14.052  1.00 38.61  ? 411  GLN B N   1 
ATOM   6660  C CA  . GLN B 1 418 ? 33.886  -20.957 -13.354  1.00 39.08  ? 411  GLN B CA  1 
ATOM   6661  C C   . GLN B 1 418 ? 33.448  -19.651 -12.689  1.00 38.22  ? 411  GLN B C   1 
ATOM   6662  O O   . GLN B 1 418 ? 34.340  -18.851 -12.311  1.00 36.59  ? 411  GLN B O   1 
ATOM   6663  C CB  . GLN B 1 418 ? 35.002  -20.730 -14.359  1.00 38.90  ? 411  GLN B CB  1 
ATOM   6664  C CG  . GLN B 1 418 ? 35.532  -22.027 -14.942  1.00 40.90  ? 411  GLN B CG  1 
ATOM   6665  C CD  . GLN B 1 418 ? 36.606  -21.705 -15.941  1.00 43.91  ? 411  GLN B CD  1 
ATOM   6666  O OE1 . GLN B 1 418 ? 37.674  -21.220 -15.573  1.00 46.64  ? 411  GLN B OE1 1 
ATOM   6667  N NE2 . GLN B 1 418 ? 36.296  -21.915 -17.213  1.00 47.83  ? 411  GLN B NE2 1 
ATOM   6668  N N   . ARG B 1 419 ? 32.137  -19.449 -12.532  1.00 34.29  ? 412  ARG B N   1 
ATOM   6669  C CA  . ARG B 1 419 ? 31.557  -18.328 -11.753  1.00 35.16  ? 412  ARG B CA  1 
ATOM   6670  C C   . ARG B 1 419 ? 31.942  -16.996 -12.404  1.00 30.18  ? 412  ARG B C   1 
ATOM   6671  O O   . ARG B 1 419 ? 32.224  -16.034 -11.672  1.00 26.66  ? 412  ARG B O   1 
ATOM   6672  C CB  . ARG B 1 419 ? 31.975  -18.419 -10.276  1.00 40.21  ? 412  ARG B CB  1 
ATOM   6673  C CG  . ARG B 1 419 ? 31.515  -19.674 -9.539   1.00 44.43  ? 412  ARG B CG  1 
ATOM   6674  C CD  . ARG B 1 419 ? 30.245  -20.246 -10.117  1.00 51.05  ? 412  ARG B CD  1 
ATOM   6675  N NE  . ARG B 1 419 ? 29.834  -21.514 -9.524   1.00 59.51  ? 412  ARG B NE  1 
ATOM   6676  C CZ  . ARG B 1 419 ? 29.004  -22.385 -10.104  1.00 62.20  ? 412  ARG B CZ  1 
ATOM   6677  N NH1 . ARG B 1 419 ? 28.536  -22.151 -11.324  1.00 62.59  ? 412  ARG B NH1 1 
ATOM   6678  N NH2 . ARG B 1 419 ? 28.658  -23.498 -9.473   1.00 61.78  ? 412  ARG B NH2 1 
ATOM   6679  N N   . VAL B 1 420 ? 31.919  -16.938 -13.736  1.00 30.09  ? 413  VAL B N   1 
ATOM   6680  C CA  . VAL B 1 420 ? 32.002  -15.661 -14.498  1.00 30.28  ? 413  VAL B CA  1 
ATOM   6681  C C   . VAL B 1 420 ? 30.798  -15.576 -15.423  1.00 31.15  ? 413  VAL B C   1 
ATOM   6682  O O   . VAL B 1 420 ? 30.579  -16.500 -16.225  1.00 28.89  ? 413  VAL B O   1 
ATOM   6683  C CB  . VAL B 1 420 ? 33.306  -15.510 -15.291  1.00 32.78  ? 413  VAL B CB  1 
ATOM   6684  C CG1 . VAL B 1 420 ? 33.340  -14.186 -16.031  1.00 33.65  ? 413  VAL B CG1 1 
ATOM   6685  C CG2 . VAL B 1 420 ? 34.526  -15.641 -14.402  1.00 32.64  ? 413  VAL B CG2 1 
ATOM   6686  N N   . LEU B 1 421 ? 30.069  -14.475 -15.295  1.00 32.64  ? 414  LEU B N   1 
ATOM   6687  C CA  . LEU B 1 421 ? 28.727  -14.290 -15.882  1.00 35.75  ? 414  LEU B CA  1 
ATOM   6688  C C   . LEU B 1 421 ? 28.871  -13.509 -17.186  1.00 34.19  ? 414  LEU B C   1 
ATOM   6689  O O   . LEU B 1 421 ? 29.276  -12.334 -17.140  1.00 34.16  ? 414  LEU B O   1 
ATOM   6690  C CB  . LEU B 1 421 ? 27.875  -13.540 -14.856  1.00 38.80  ? 414  LEU B CB  1 
ATOM   6691  C CG  . LEU B 1 421 ? 26.397  -13.403 -15.174  1.00 44.31  ? 414  LEU B CG  1 
ATOM   6692  C CD1 . LEU B 1 421 ? 25.794  -14.763 -15.507  1.00 50.51  ? 414  LEU B CD1 1 
ATOM   6693  C CD2 . LEU B 1 421 ? 25.672  -12.768 -13.997  1.00 44.59  ? 414  LEU B CD2 1 
ATOM   6694  N N   . VAL B 1 422 ? 28.585  -14.179 -18.298  1.00 35.68  ? 415  VAL B N   1 
ATOM   6695  C CA  . VAL B 1 422 ? 28.480  -13.593 -19.666  1.00 36.76  ? 415  VAL B CA  1 
ATOM   6696  C C   . VAL B 1 422 ? 27.178  -14.111 -20.281  1.00 36.85  ? 415  VAL B C   1 
ATOM   6697  O O   . VAL B 1 422 ? 26.603  -15.063 -19.718  1.00 33.86  ? 415  VAL B O   1 
ATOM   6698  C CB  . VAL B 1 422 ? 29.690  -13.998 -20.518  1.00 38.04  ? 415  VAL B CB  1 
ATOM   6699  C CG1 . VAL B 1 422 ? 30.982  -13.478 -19.916  1.00 41.65  ? 415  VAL B CG1 1 
ATOM   6700  C CG2 . VAL B 1 422 ? 29.756  -15.511 -20.692  1.00 38.08  ? 415  VAL B CG2 1 
ATOM   6701  N N   . ALA B 1 423 ? 26.745  -13.564 -21.412  1.00 38.42  ? 416  ALA B N   1 
ATOM   6702  C CA  . ALA B 1 423 ? 25.579  -14.106 -22.143  1.00 43.12  ? 416  ALA B CA  1 
ATOM   6703  C C   . ALA B 1 423 ? 25.617  -13.616 -23.573  1.00 43.96  ? 416  ALA B C   1 
ATOM   6704  O O   . ALA B 1 423 ? 26.447  -12.763 -23.843  1.00 45.43  ? 416  ALA B O   1 
ATOM   6705  C CB  . ALA B 1 423 ? 24.299  -13.683 -21.477  1.00 42.91  ? 416  ALA B CB  1 
ATOM   6706  N N   . GLY B 1 424 ? 24.715  -14.125 -24.412  1.00 51.75  ? 417  GLY B N   1 
ATOM   6707  C CA  . GLY B 1 424 ? 24.625  -13.791 -25.846  1.00 55.72  ? 417  GLY B CA  1 
ATOM   6708  C C   . GLY B 1 424 ? 24.057  -12.402 -26.114  1.00 59.95  ? 417  GLY B C   1 
ATOM   6709  O O   . GLY B 1 424 ? 23.463  -11.794 -25.195  1.00 55.31  ? 417  GLY B O   1 
ATOM   6710  N N   . THR B 1 425 ? 24.243  -11.925 -27.352  1.00 72.99  ? 418  THR B N   1 
ATOM   6711  C CA  . THR B 1 425 ? 23.642  -10.688 -27.934  1.00 77.02  ? 418  THR B CA  1 
ATOM   6712  C C   . THR B 1 425 ? 22.301  -11.046 -28.606  1.00 81.46  ? 418  THR B C   1 
ATOM   6713  O O   . THR B 1 425 ? 22.099  -12.252 -28.945  1.00 81.80  ? 418  THR B O   1 
ATOM   6714  C CB  . THR B 1 425 ? 24.623  -9.990  -28.897  1.00 70.23  ? 418  THR B CB  1 
ATOM   6715  O OG1 . THR B 1 425 ? 25.111  -10.946 -29.838  1.00 60.01  ? 418  THR B OG1 1 
ATOM   6716  C CG2 . THR B 1 425 ? 25.798  -9.344  -28.191  1.00 72.64  ? 418  THR B CG2 1 
ATOM   6717  N N   . LEU B 1 426 ? 21.418  -10.049 -28.783  1.00 81.29  ? 419  LEU B N   1 
ATOM   6718  C CA  . LEU B 1 426 ? 20.061  -10.233 -29.371  1.00 84.93  ? 419  LEU B CA  1 
ATOM   6719  C C   . LEU B 1 426 ? 20.183  -10.343 -30.906  1.00 88.47  ? 419  LEU B C   1 
ATOM   6720  O O   . LEU B 1 426 ? 19.974  -11.464 -31.424  1.00 92.00  ? 419  LEU B O   1 
ATOM   6721  C CB  . LEU B 1 426 ? 19.126  -9.101  -28.907  1.00 80.28  ? 419  LEU B CB  1 
ATOM   6722  C CG  . LEU B 1 426 ? 18.547  -9.209  -27.484  1.00 78.95  ? 419  LEU B CG  1 
ATOM   6723  C CD1 . LEU B 1 426 ? 17.751  -7.955  -27.113  1.00 74.76  ? 419  LEU B CD1 1 
ATOM   6724  C CD2 . LEU B 1 426 ? 17.670  -10.449 -27.301  1.00 74.40  ? 419  LEU B CD2 1 
ATOM   6725  N N   . ASN B 1 427 ? 20.577  -9.277  -31.617  1.00 93.28  ? 420  ASN B N   1 
ATOM   6726  C CA  . ASN B 1 427 ? 20.568  -9.231  -33.112  1.00 91.19  ? 420  ASN B CA  1 
ATOM   6727  C C   . ASN B 1 427 ? 21.842  -9.878  -33.682  1.00 87.22  ? 420  ASN B C   1 
ATOM   6728  O O   . ASN B 1 427 ? 22.332  -9.379  -34.718  1.00 87.25  ? 420  ASN B O   1 
ATOM   6729  C CB  . ASN B 1 427 ? 20.397  -7.801  -33.647  1.00 87.06  ? 420  ASN B CB  1 
ATOM   6730  C CG  . ASN B 1 427 ? 19.189  -7.095  -33.058  1.00 87.69  ? 420  ASN B CG  1 
ATOM   6731  O OD1 . ASN B 1 427 ? 18.619  -7.560  -32.070  1.00 92.53  ? 420  ASN B OD1 1 
ATOM   6732  N ND2 . ASN B 1 427 ? 18.787  -5.983  -33.653  1.00 79.83  ? 420  ASN B ND2 1 
ATOM   6733  N N   . ASN B 1 428 ? 22.345  -10.952 -33.054  1.00 86.10  ? 421  ASN B N   1 
ATOM   6734  C CA  . ASN B 1 428 ? 23.618  -11.633 -33.427  1.00 87.21  ? 421  ASN B CA  1 
ATOM   6735  C C   . ASN B 1 428 ? 23.795  -12.916 -32.594  1.00 88.35  ? 421  ASN B C   1 
ATOM   6736  O O   . ASN B 1 428 ? 24.095  -12.810 -31.391  1.00 98.31  ? 421  ASN B O   1 
ATOM   6737  C CB  . ASN B 1 428 ? 24.834  -10.705 -33.268  1.00 88.26  ? 421  ASN B CB  1 
ATOM   6738  C CG  . ASN B 1 428 ? 26.078  -11.197 -33.990  1.00 89.53  ? 421  ASN B CG  1 
ATOM   6739  O OD1 . ASN B 1 428 ? 26.173  -12.358 -34.385  1.00 87.07  ? 421  ASN B OD1 1 
ATOM   6740  N ND2 . ASN B 1 428 ? 27.047  -10.315 -34.182  1.00 88.03  ? 421  ASN B ND2 1 
ATOM   6741  N N   . ALA B 1 429 ? 23.638  -14.085 -33.220  1.00 86.27  ? 422  ALA B N   1 
ATOM   6742  C CA  . ALA B 1 429 ? 23.911  -15.422 -32.629  1.00 81.69  ? 422  ALA B CA  1 
ATOM   6743  C C   . ALA B 1 429 ? 25.430  -15.644 -32.536  1.00 85.40  ? 422  ALA B C   1 
ATOM   6744  O O   . ALA B 1 429 ? 26.171  -14.858 -33.155  1.00 90.91  ? 422  ALA B O   1 
ATOM   6745  C CB  . ALA B 1 429 ? 23.239  -16.480 -33.472  1.00 78.45  ? 422  ALA B CB  1 
ATOM   6746  N N   . LYS B 1 430 ? 25.890  -16.650 -31.770  1.00 81.24  ? 423  LYS B N   1 
ATOM   6747  C CA  . LYS B 1 430 ? 27.316  -17.124 -31.730  1.00 61.37  ? 423  LYS B CA  1 
ATOM   6748  C C   . LYS B 1 430 ? 28.268  -16.024 -31.242  1.00 46.19  ? 423  LYS B C   1 
ATOM   6749  O O   . LYS B 1 430 ? 29.491  -16.246 -31.302  1.00 41.35  ? 423  LYS B O   1 
ATOM   6750  C CB  . LYS B 1 430 ? 27.758  -17.653 -33.109  1.00 62.08  ? 423  LYS B CB  1 
ATOM   6751  C CG  . LYS B 1 430 ? 28.234  -16.633 -34.142  1.00 59.27  ? 423  LYS B CG  1 
ATOM   6752  C CD  . LYS B 1 430 ? 27.939  -17.037 -35.565  1.00 58.15  ? 423  LYS B CD  1 
ATOM   6753  C CE  . LYS B 1 430 ? 28.825  -16.319 -36.560  1.00 65.95  ? 423  LYS B CE  1 
ATOM   6754  N NZ  . LYS B 1 430 ? 30.215  -16.847 -36.567  1.00 74.41  ? 423  LYS B NZ  1 
ATOM   6755  N N   . THR B 1 431 ? 27.727  -14.910 -30.743  1.00 37.41  ? 424  THR B N   1 
ATOM   6756  C CA  . THR B 1 431 ? 28.464  -13.715 -30.259  1.00 35.61  ? 424  THR B CA  1 
ATOM   6757  C C   . THR B 1 431 ? 28.127  -13.520 -28.777  1.00 32.58  ? 424  THR B C   1 
ATOM   6758  O O   . THR B 1 431 ? 26.924  -13.447 -28.434  1.00 35.54  ? 424  THR B O   1 
ATOM   6759  C CB  . THR B 1 431 ? 28.150  -12.492 -31.128  1.00 33.64  ? 424  THR B CB  1 
ATOM   6760  O OG1 . THR B 1 431 ? 28.586  -12.860 -32.431  1.00 41.23  ? 424  THR B OG1 1 
ATOM   6761  C CG2 . THR B 1 431 ? 28.862  -11.224 -30.715  1.00 35.67  ? 424  THR B CG2 1 
ATOM   6762  N N   . ILE B 1 432 ? 29.151  -13.481 -27.929  1.00 28.05  ? 425  ILE B N   1 
ATOM   6763  C CA  . ILE B 1 432 ? 29.014  -13.312 -26.456  1.00 25.19  ? 425  ILE B CA  1 
ATOM   6764  C C   . ILE B 1 432 ? 29.445  -11.890 -26.117  1.00 24.05  ? 425  ILE B C   1 
ATOM   6765  O O   . ILE B 1 432 ? 30.557  -11.516 -26.472  1.00 23.06  ? 425  ILE B O   1 
ATOM   6766  C CB  . ILE B 1 432 ? 29.854  -14.383 -25.746  1.00 25.79  ? 425  ILE B CB  1 
ATOM   6767  C CG1 . ILE B 1 432 ? 29.378  -15.790 -26.114  1.00 25.13  ? 425  ILE B CG1 1 
ATOM   6768  C CG2 . ILE B 1 432 ? 29.869  -14.160 -24.242  1.00 28.08  ? 425  ILE B CG2 1 
ATOM   6769  C CD1 . ILE B 1 432 ? 28.060  -16.178 -25.497  1.00 23.48  ? 425  ILE B CD1 1 
ATOM   6770  N N   . ARG B 1 433 ? 28.569  -11.121 -25.484  1.00 27.23  ? 426  ARG B N   1 
ATOM   6771  C CA  . ARG B 1 433 ? 28.867  -9.746  -25.007  1.00 32.69  ? 426  ARG B CA  1 
ATOM   6772  C C   . ARG B 1 433 ? 29.703  -9.834  -23.727  1.00 31.90  ? 426  ARG B C   1 
ATOM   6773  O O   . ARG B 1 433 ? 29.438  -10.712 -22.868  1.00 36.29  ? 426  ARG B O   1 
ATOM   6774  C CB  . ARG B 1 433 ? 27.589  -8.942  -24.754  1.00 39.72  ? 426  ARG B CB  1 
ATOM   6775  C CG  . ARG B 1 433 ? 26.770  -9.396  -23.547  1.00 48.43  ? 426  ARG B CG  1 
ATOM   6776  C CD  . ARG B 1 433 ? 25.413  -8.734  -23.398  1.00 56.59  ? 426  ARG B CD  1 
ATOM   6777  N NE  . ARG B 1 433 ? 24.790  -8.491  -24.708  1.00 68.01  ? 426  ARG B NE  1 
ATOM   6778  C CZ  . ARG B 1 433 ? 24.147  -7.383  -25.076  1.00 66.16  ? 426  ARG B CZ  1 
ATOM   6779  N NH1 . ARG B 1 433 ? 23.988  -6.368  -24.237  1.00 69.76  ? 426  ARG B NH1 1 
ATOM   6780  N NH2 . ARG B 1 433 ? 23.668  -7.294  -26.299  1.00 64.18  ? 426  ARG B NH2 1 
ATOM   6781  N N   . ILE B 1 434 ? 30.712  -8.980  -23.620  1.00 28.11  ? 427  ILE B N   1 
ATOM   6782  C CA  . ILE B 1 434 ? 31.439  -8.741  -22.357  1.00 27.17  ? 427  ILE B CA  1 
ATOM   6783  C C   . ILE B 1 434 ? 31.183  -7.286  -21.999  1.00 25.91  ? 427  ILE B C   1 
ATOM   6784  O O   . ILE B 1 434 ? 31.715  -6.395  -22.687  1.00 25.30  ? 427  ILE B O   1 
ATOM   6785  C CB  . ILE B 1 434 ? 32.928  -9.065  -22.514  1.00 29.81  ? 427  ILE B CB  1 
ATOM   6786  C CG1 . ILE B 1 434 ? 33.157  -10.456 -23.116  1.00 30.20  ? 427  ILE B CG1 1 
ATOM   6787  C CG2 . ILE B 1 434 ? 33.628  -8.895  -21.177  1.00 29.98  ? 427  ILE B CG2 1 
ATOM   6788  C CD1 . ILE B 1 434 ? 32.798  -11.591 -22.181  1.00 32.28  ? 427  ILE B CD1 1 
ATOM   6789  N N   . GLU B 1 435 ? 30.343  -7.080  -20.989  1.00 25.42  ? 428  GLU B N   1 
ATOM   6790  C CA  . GLU B 1 435 ? 29.841  -5.750  -20.564  1.00 26.56  ? 428  GLU B CA  1 
ATOM   6791  C C   . GLU B 1 435 ? 29.944  -5.648  -19.046  1.00 22.77  ? 428  GLU B C   1 
ATOM   6792  O O   . GLU B 1 435 ? 28.932  -5.538  -18.369  1.00 21.34  ? 428  GLU B O   1 
ATOM   6793  C CB  . GLU B 1 435 ? 28.393  -5.569  -21.036  1.00 27.94  ? 428  GLU B CB  1 
ATOM   6794  C CG  . GLU B 1 435 ? 28.271  -4.866  -22.373  1.00 30.89  ? 428  GLU B CG  1 
ATOM   6795  C CD  . GLU B 1 435 ? 26.845  -4.503  -22.757  1.00 33.36  ? 428  GLU B CD  1 
ATOM   6796  O OE1 . GLU B 1 435 ? 26.339  -3.451  -22.277  1.00 32.73  ? 428  GLU B OE1 1 
ATOM   6797  O OE2 . GLU B 1 435 ? 26.233  -5.280  -23.519  1.00 36.62  ? 428  GLU B OE2 1 
ATOM   6798  N N   . PRO B 1 436 ? 31.158  -5.694  -18.464  1.00 21.40  ? 429  PRO B N   1 
ATOM   6799  C CA  . PRO B 1 436 ? 31.293  -5.679  -17.013  1.00 21.61  ? 429  PRO B CA  1 
ATOM   6800  C C   . PRO B 1 436 ? 31.038  -4.280  -16.467  1.00 21.17  ? 429  PRO B C   1 
ATOM   6801  O O   . PRO B 1 436 ? 31.088  -3.294  -17.196  1.00 20.20  ? 429  PRO B O   1 
ATOM   6802  C CB  . PRO B 1 436 ? 32.746  -6.095  -16.741  1.00 21.67  ? 429  PRO B CB  1 
ATOM   6803  C CG  . PRO B 1 436 ? 33.337  -6.432  -18.103  1.00 21.01  ? 429  PRO B CG  1 
ATOM   6804  C CD  . PRO B 1 436 ? 32.461  -5.739  -19.130  1.00 20.85  ? 429  PRO B CD  1 
ATOM   6805  N N   . PRO B 1 437 ? 30.759  -4.154  -15.158  1.00 21.46  ? 430  PRO B N   1 
ATOM   6806  C CA  . PRO B 1 437 ? 30.770  -2.849  -14.508  1.00 21.15  ? 430  PRO B CA  1 
ATOM   6807  C C   . PRO B 1 437 ? 32.072  -2.099  -14.797  1.00 19.83  ? 430  PRO B C   1 
ATOM   6808  O O   . PRO B 1 437 ? 33.078  -2.743  -14.815  1.00 18.04  ? 430  PRO B O   1 
ATOM   6809  C CB  . PRO B 1 437 ? 30.700  -3.208  -13.022  1.00 23.07  ? 430  PRO B CB  1 
ATOM   6810  C CG  . PRO B 1 437 ? 29.969  -4.534  -13.004  1.00 22.69  ? 430  PRO B CG  1 
ATOM   6811  C CD  . PRO B 1 437 ? 30.416  -5.253  -14.249  1.00 21.37  ? 430  PRO B CD  1 
ATOM   6812  N N   . LEU B 1 438 ? 32.008  -0.779  -14.983  1.00 19.54  ? 431  LEU B N   1 
ATOM   6813  C CA  . LEU B 1 438 ? 33.201  0.069   -15.216  1.00 20.35  ? 431  LEU B CA  1 
ATOM   6814  C C   . LEU B 1 438 ? 34.107  -0.045  -13.987  1.00 21.24  ? 431  LEU B C   1 
ATOM   6815  O O   . LEU B 1 438 ? 35.319  0.214   -14.125  1.00 20.48  ? 431  LEU B O   1 
ATOM   6816  C CB  . LEU B 1 438 ? 32.784  1.522   -15.477  1.00 20.78  ? 431  LEU B CB  1 
ATOM   6817  C CG  . LEU B 1 438 ? 31.707  1.724   -16.545  1.00 22.22  ? 431  LEU B CG  1 
ATOM   6818  C CD1 . LEU B 1 438 ? 31.660  3.171   -17.035  1.00 22.53  ? 431  LEU B CD1 1 
ATOM   6819  C CD2 . LEU B 1 438 ? 31.901  0.774   -17.722  1.00 22.17  ? 431  LEU B CD2 1 
ATOM   6820  N N   . THR B 1 439 ? 33.534  -0.471  -12.854  1.00 22.34  ? 432  THR B N   1 
ATOM   6821  C CA  . THR B 1 439 ? 34.192  -0.597  -11.528  1.00 22.09  ? 432  THR B CA  1 
ATOM   6822  C C   . THR B 1 439 ? 34.928  -1.935  -11.396  1.00 21.01  ? 432  THR B C   1 
ATOM   6823  O O   . THR B 1 439 ? 35.556  -2.154  -10.329  1.00 20.53  ? 432  THR B O   1 
ATOM   6824  C CB  . THR B 1 439 ? 33.136  -0.444  -10.425  1.00 22.11  ? 432  THR B CB  1 
ATOM   6825  O OG1 . THR B 1 439 ? 32.100  -1.388  -10.695  1.00 21.42  ? 432  THR B OG1 1 
ATOM   6826  C CG2 . THR B 1 439 ? 32.573  0.957   -10.370  1.00 22.09  ? 432  THR B CG2 1 
ATOM   6827  N N   . LEU B 1 440 ? 34.874  -2.797  -12.413  1.00 19.38  ? 433  LEU B N   1 
ATOM   6828  C CA  . LEU B 1 440 ? 35.616  -4.078  -12.384  1.00 20.00  ? 433  LEU B CA  1 
ATOM   6829  C C   . LEU B 1 440 ? 37.077  -3.795  -12.016  1.00 21.28  ? 433  LEU B C   1 
ATOM   6830  O O   . LEU B 1 440 ? 37.681  -2.912  -12.629  1.00 20.61  ? 433  LEU B O   1 
ATOM   6831  C CB  . LEU B 1 440 ? 35.529  -4.762  -13.741  1.00 19.48  ? 433  LEU B CB  1 
ATOM   6832  C CG  . LEU B 1 440 ? 35.970  -6.217  -13.746  1.00 19.35  ? 433  LEU B CG  1 
ATOM   6833  C CD1 . LEU B 1 440 ? 34.985  -7.086  -12.967  1.00 19.56  ? 433  LEU B CD1 1 
ATOM   6834  C CD2 . LEU B 1 440 ? 36.150  -6.704  -15.182  1.00 18.80  ? 433  LEU B CD2 1 
ATOM   6835  N N   . THR B 1 441 ? 37.620  -4.492  -11.022  1.00 21.83  ? 434  THR B N   1 
ATOM   6836  C CA  . THR B 1 441 ? 38.995  -4.231  -10.539  1.00 22.99  ? 434  THR B CA  1 
ATOM   6837  C C   . THR B 1 441 ? 39.981  -4.847  -11.526  1.00 23.89  ? 434  THR B C   1 
ATOM   6838  O O   . THR B 1 441 ? 39.611  -5.783  -12.260  1.00 23.31  ? 434  THR B O   1 
ATOM   6839  C CB  . THR B 1 441 ? 39.263  -4.785  -9.135   1.00 22.62  ? 434  THR B CB  1 
ATOM   6840  O OG1 . THR B 1 441 ? 39.353  -6.210  -9.218   1.00 22.29  ? 434  THR B OG1 1 
ATOM   6841  C CG2 . THR B 1 441 ? 38.217  -4.363  -8.129   1.00 23.08  ? 434  THR B CG2 1 
ATOM   6842  N N   . ILE B 1 442 ? 41.211  -4.353  -11.503  1.00 24.53  ? 435  ILE B N   1 
ATOM   6843  C CA  . ILE B 1 442 ? 42.285  -4.872  -12.371  1.00 26.67  ? 435  ILE B CA  1 
ATOM   6844  C C   . ILE B 1 442 ? 42.443  -6.360  -12.091  1.00 26.01  ? 435  ILE B C   1 
ATOM   6845  O O   . ILE B 1 442 ? 42.578  -7.106  -13.045  1.00 27.16  ? 435  ILE B O   1 
ATOM   6846  C CB  . ILE B 1 442 ? 43.582  -4.091  -12.138  1.00 31.26  ? 435  ILE B CB  1 
ATOM   6847  C CG1 . ILE B 1 442 ? 43.356  -2.584  -12.326  1.00 33.35  ? 435  ILE B CG1 1 
ATOM   6848  C CG2 . ILE B 1 442 ? 44.682  -4.630  -13.051  1.00 31.61  ? 435  ILE B CG2 1 
ATOM   6849  C CD1 . ILE B 1 442 ? 42.945  -2.188  -13.737  1.00 32.56  ? 435  ILE B CD1 1 
ATOM   6850  N N   . GLU B 1 443 ? 42.419  -6.771  -10.832  1.00 27.69  ? 436  GLU B N   1 
ATOM   6851  C CA  . GLU B 1 443 ? 42.557  -8.210  -10.500  1.00 30.70  ? 436  GLU B CA  1 
ATOM   6852  C C   . GLU B 1 443 ? 41.392  -8.976  -11.115  1.00 28.67  ? 436  GLU B C   1 
ATOM   6853  O O   . GLU B 1 443 ? 41.666  -10.023 -11.683  1.00 28.77  ? 436  GLU B O   1 
ATOM   6854  C CB  . GLU B 1 443 ? 42.637  -8.523  -9.008   1.00 38.14  ? 436  GLU B CB  1 
ATOM   6855  C CG  . GLU B 1 443 ? 43.485  -9.782  -8.770   1.00 44.14  ? 436  GLU B CG  1 
ATOM   6856  C CD  . GLU B 1 443 ? 43.024  -10.736 -7.667   1.00 50.97  ? 436  GLU B CD  1 
ATOM   6857  O OE1 . GLU B 1 443 ? 42.453  -10.243 -6.665   1.00 52.89  ? 436  GLU B OE1 1 
ATOM   6858  O OE2 . GLU B 1 443 ? 43.243  -11.979 -7.801   1.00 51.21  ? 436  GLU B OE2 1 
ATOM   6859  N N   . GLN B 1 444 ? 40.156  -8.481  -11.024  1.00 26.01  ? 437  GLN B N   1 
ATOM   6860  C CA  . GLN B 1 444 ? 38.994  -9.173  -11.632  1.00 25.83  ? 437  GLN B CA  1 
ATOM   6861  C C   . GLN B 1 444 ? 39.208  -9.260  -13.141  1.00 25.42  ? 437  GLN B C   1 
ATOM   6862  O O   . GLN B 1 444 ? 39.048  -10.372 -13.679  1.00 24.02  ? 437  GLN B O   1 
ATOM   6863  C CB  . GLN B 1 444 ? 37.671  -8.508  -11.247  1.00 25.65  ? 437  GLN B CB  1 
ATOM   6864  C CG  . GLN B 1 444 ? 37.288  -8.850  -9.815   1.00 25.92  ? 437  GLN B CG  1 
ATOM   6865  C CD  . GLN B 1 444 ? 36.299  -7.904  -9.187   1.00 26.08  ? 437  GLN B CD  1 
ATOM   6866  O OE1 . GLN B 1 444 ? 36.218  -6.724  -9.527   1.00 25.15  ? 437  GLN B OE1 1 
ATOM   6867  N NE2 . GLN B 1 444 ? 35.530  -8.426  -8.249   1.00 26.24  ? 437  GLN B NE2 1 
ATOM   6868  N N   . CYS B 1 445 ? 39.594  -8.156  -13.796  1.00 28.07  ? 438  CYS B N   1 
ATOM   6869  C CA  . CYS B 1 445 ? 39.947  -8.132  -15.248  1.00 28.26  ? 438  CYS B CA  1 
ATOM   6870  C C   . CYS B 1 445 ? 40.827  -9.348  -15.557  1.00 28.14  ? 438  CYS B C   1 
ATOM   6871  O O   . CYS B 1 445 ? 40.465  -10.112 -16.442  1.00 31.58  ? 438  CYS B O   1 
ATOM   6872  C CB  . CYS B 1 445 ? 40.691  -6.866  -15.677  1.00 28.33  ? 438  CYS B CB  1 
ATOM   6873  S SG  . CYS B 1 445 ? 39.663  -5.379  -15.691  1.00 27.98  ? 438  CYS B SG  1 
ATOM   6874  N N   . GLU B 1 446 ? 41.916  -9.530  -14.814  1.00 26.15  ? 439  GLU B N   1 
ATOM   6875  C CA  . GLU B 1 446 ? 42.884  -10.636 -15.013  1.00 28.48  ? 439  GLU B CA  1 
ATOM   6876  C C   . GLU B 1 446 ? 42.194  -11.978 -14.792  1.00 27.62  ? 439  GLU B C   1 
ATOM   6877  O O   . GLU B 1 446 ? 42.430  -12.873 -15.589  1.00 31.61  ? 439  GLU B O   1 
ATOM   6878  C CB  . GLU B 1 446 ? 44.095  -10.464 -14.101  1.00 29.68  ? 439  GLU B CB  1 
ATOM   6879  C CG  . GLU B 1 446 ? 44.968  -9.288  -14.532  1.00 32.62  ? 439  GLU B CG  1 
ATOM   6880  C CD  . GLU B 1 446 ? 46.137  -8.944  -13.623  1.00 36.07  ? 439  GLU B CD  1 
ATOM   6881  O OE1 . GLU B 1 446 ? 46.582  -9.839  -12.874  1.00 37.73  ? 439  GLU B OE1 1 
ATOM   6882  O OE2 . GLU B 1 446 ? 46.597  -7.778  -13.669  1.00 41.71  ? 439  GLU B OE2 1 
ATOM   6883  N N   . LEU B 1 447 ? 41.378  -12.112 -13.757  1.00 28.54  ? 440  LEU B N   1 
ATOM   6884  C CA  . LEU B 1 447 ? 40.638  -13.367 -13.447  1.00 29.92  ? 440  LEU B CA  1 
ATOM   6885  C C   . LEU B 1 447 ? 39.703  -13.700 -14.606  1.00 29.66  ? 440  LEU B C   1 
ATOM   6886  O O   . LEU B 1 447 ? 39.572  -14.890 -14.923  1.00 32.29  ? 440  LEU B O   1 
ATOM   6887  C CB  . LEU B 1 447 ? 39.847  -13.204 -12.145  1.00 31.72  ? 440  LEU B CB  1 
ATOM   6888  C CG  . LEU B 1 447 ? 40.706  -13.119 -10.882  1.00 32.71  ? 440  LEU B CG  1 
ATOM   6889  C CD1 . LEU B 1 447 ? 39.838  -12.933 -9.640   1.00 32.50  ? 440  LEU B CD1 1 
ATOM   6890  C CD2 . LEU B 1 447 ? 41.590  -14.361 -10.762  1.00 32.53  ? 440  LEU B CD2 1 
ATOM   6891  N N   . VAL B 1 448 ? 39.086  -12.684 -15.205  1.00 26.28  ? 441  VAL B N   1 
ATOM   6892  C CA  . VAL B 1 448 ? 38.158  -12.853 -16.356  1.00 26.98  ? 441  VAL B CA  1 
ATOM   6893  C C   . VAL B 1 448 ? 38.934  -13.484 -17.526  1.00 23.79  ? 441  VAL B C   1 
ATOM   6894  O O   . VAL B 1 448 ? 38.491  -14.512 -18.059  1.00 20.77  ? 441  VAL B O   1 
ATOM   6895  C CB  . VAL B 1 448 ? 37.496  -11.513 -16.737  1.00 27.26  ? 441  VAL B CB  1 
ATOM   6896  C CG1 . VAL B 1 448 ? 36.781  -11.602 -18.068  1.00 27.08  ? 441  VAL B CG1 1 
ATOM   6897  C CG2 . VAL B 1 448 ? 36.540  -11.039 -15.663  1.00 26.03  ? 441  VAL B CG2 1 
ATOM   6898  N N   . ILE B 1 449 ? 40.086  -12.915 -17.863  1.00 24.32  ? 442  ILE B N   1 
ATOM   6899  C CA  . ILE B 1 449 ? 40.960  -13.404 -18.964  1.00 23.43  ? 442  ILE B CA  1 
ATOM   6900  C C   . ILE B 1 449 ? 41.384  -14.845 -18.666  1.00 23.88  ? 442  ILE B C   1 
ATOM   6901  O O   . ILE B 1 449 ? 41.358  -15.652 -19.600  1.00 22.79  ? 442  ILE B O   1 
ATOM   6902  C CB  . ILE B 1 449 ? 42.166  -12.471 -19.153  1.00 23.98  ? 442  ILE B CB  1 
ATOM   6903  C CG1 . ILE B 1 449 ? 41.750  -11.053 -19.549  1.00 23.63  ? 442  ILE B CG1 1 
ATOM   6904  C CG2 . ILE B 1 449 ? 43.154  -13.073 -20.147  1.00 24.45  ? 442  ILE B CG2 1 
ATOM   6905  C CD1 . ILE B 1 449 ? 40.958  -10.965 -20.817  1.00 24.56  ? 442  ILE B CD1 1 
ATOM   6906  N N   . LYS B 1 450 ? 41.734  -15.162 -17.417  1.00 26.25  ? 443  LYS B N   1 
ATOM   6907  C CA  . LYS B 1 450 ? 42.190  -16.521 -17.023  1.00 29.27  ? 443  LYS B CA  1 
ATOM   6908  C C   . LYS B 1 450 ? 41.019  -17.491 -17.167  1.00 27.52  ? 443  LYS B C   1 
ATOM   6909  O O   . LYS B 1 450 ? 41.247  -18.599 -17.681  1.00 26.75  ? 443  LYS B O   1 
ATOM   6910  C CB  . LYS B 1 450 ? 42.691  -16.571 -15.580  1.00 32.49  ? 443  LYS B CB  1 
ATOM   6911  C CG  . LYS B 1 450 ? 44.001  -15.864 -15.293  1.00 40.47  ? 443  LYS B CG  1 
ATOM   6912  C CD  . LYS B 1 450 ? 44.245  -15.719 -13.785  1.00 45.95  ? 443  LYS B CD  1 
ATOM   6913  C CE  . LYS B 1 450 ? 45.169  -14.573 -13.417  1.00 49.70  ? 443  LYS B CE  1 
ATOM   6914  N NZ  . LYS B 1 450 ? 46.407  -14.556 -14.246  1.00 49.24  ? 443  LYS B NZ  1 
ATOM   6915  N N   . ALA B 1 451 ? 39.818  -17.085 -16.740  1.00 26.22  ? 444  ALA B N   1 
ATOM   6916  C CA  . ALA B 1 451 ? 38.572  -17.875 -16.869  1.00 25.39  ? 444  ALA B CA  1 
ATOM   6917  C C   . ALA B 1 451 ? 38.297  -18.151 -18.345  1.00 26.72  ? 444  ALA B C   1 
ATOM   6918  O O   . ALA B 1 451 ? 37.983  -19.304 -18.689  1.00 26.31  ? 444  ALA B O   1 
ATOM   6919  C CB  . ALA B 1 451 ? 37.435  -17.148 -16.225  1.00 24.31  ? 444  ALA B CB  1 
ATOM   6920  N N   . ALA B 1 452 ? 38.422  -17.132 -19.196  1.00 28.58  ? 445  ALA B N   1 
ATOM   6921  C CA  . ALA B 1 452 ? 38.203  -17.259 -20.652  1.00 29.66  ? 445  ALA B CA  1 
ATOM   6922  C C   . ALA B 1 452 ? 39.179  -18.299 -21.191  1.00 32.79  ? 445  ALA B C   1 
ATOM   6923  O O   . ALA B 1 452 ? 38.742  -19.199 -21.934  1.00 33.42  ? 445  ALA B O   1 
ATOM   6924  C CB  . ALA B 1 452 ? 38.384  -15.928 -21.333  1.00 30.09  ? 445  ALA B CB  1 
ATOM   6925  N N   . ARG B 1 453 ? 40.457  -18.186 -20.813  1.00 33.65  ? 446  ARG B N   1 
ATOM   6926  C CA  . ARG B 1 453 ? 41.535  -19.098 -21.271  1.00 33.44  ? 446  ARG B CA  1 
ATOM   6927  C C   . ARG B 1 453 ? 41.164  -20.524 -20.872  1.00 32.66  ? 446  ARG B C   1 
ATOM   6928  O O   . ARG B 1 453 ? 41.146  -21.387 -21.735  1.00 32.09  ? 446  ARG B O   1 
ATOM   6929  C CB  . ARG B 1 453 ? 42.883  -18.675 -20.684  1.00 34.95  ? 446  ARG B CB  1 
ATOM   6930  C CG  . ARG B 1 453 ? 44.060  -19.478 -21.207  1.00 38.07  ? 446  ARG B CG  1 
ATOM   6931  C CD  . ARG B 1 453 ? 45.418  -18.913 -20.788  1.00 37.27  ? 446  ARG B CD  1 
ATOM   6932  N NE  . ARG B 1 453 ? 45.797  -17.688 -21.486  1.00 35.32  ? 446  ARG B NE  1 
ATOM   6933  C CZ  . ARG B 1 453 ? 46.179  -17.614 -22.763  1.00 39.08  ? 446  ARG B CZ  1 
ATOM   6934  N NH1 . ARG B 1 453 ? 46.215  -18.704 -23.513  1.00 41.73  ? 446  ARG B NH1 1 
ATOM   6935  N NH2 . ARG B 1 453 ? 46.512  -16.446 -23.303  1.00 37.84  ? 446  ARG B NH2 1 
ATOM   6936  N N   A LYS B 1 454 ? 40.860  -20.741 -19.595  0.50 31.50  ? 447  LYS B N   1 
ATOM   6937  N N   B LYS B 1 454 ? 40.856  -20.737 -19.594  0.50 31.66  ? 447  LYS B N   1 
ATOM   6938  C CA  A LYS B 1 454 ? 40.497  -22.073 -19.048  0.50 32.31  ? 447  LYS B CA  1 
ATOM   6939  C CA  B LYS B 1 454 ? 40.488  -22.066 -19.041  0.50 32.58  ? 447  LYS B CA  1 
ATOM   6940  C C   A LYS B 1 454 ? 39.300  -22.617 -19.833  0.50 32.71  ? 447  LYS B C   1 
ATOM   6941  C C   B LYS B 1 454 ? 39.296  -22.616 -19.831  0.50 32.86  ? 447  LYS B C   1 
ATOM   6942  O O   A LYS B 1 454 ? 39.322  -23.799 -20.163  0.50 34.01  ? 447  LYS B O   1 
ATOM   6943  O O   B LYS B 1 454 ? 39.319  -23.799 -20.165  0.50 34.13  ? 447  LYS B O   1 
ATOM   6944  C CB  A LYS B 1 454 ? 40.230  -21.981 -17.540  0.50 32.18  ? 447  LYS B CB  1 
ATOM   6945  C CB  B LYS B 1 454 ? 40.243  -21.964 -17.528  0.50 32.66  ? 447  LYS B CB  1 
ATOM   6946  C CG  A LYS B 1 454 ? 41.442  -22.267 -16.657  0.50 33.31  ? 447  LYS B CG  1 
ATOM   6947  C CG  B LYS B 1 454 ? 41.410  -22.501 -16.700  0.50 34.05  ? 447  LYS B CG  1 
ATOM   6948  C CD  A LYS B 1 454 ? 41.124  -22.549 -15.185  0.50 34.09  ? 447  LYS B CD  1 
ATOM   6949  C CD  B LYS B 1 454 ? 41.651  -21.924 -15.304  0.50 34.95  ? 447  LYS B CD  1 
ATOM   6950  C CE  A LYS B 1 454 ? 40.082  -23.631 -14.965  0.50 33.53  ? 447  LYS B CE  1 
ATOM   6951  C CE  B LYS B 1 454 ? 42.969  -22.407 -14.716  0.50 34.34  ? 447  LYS B CE  1 
ATOM   6952  N NZ  A LYS B 1 454 ? 39.512  -23.561 -13.601  0.50 32.36  ? 447  LYS B NZ  1 
ATOM   6953  N NZ  B LYS B 1 454 ? 43.342  -21.691 -13.472  0.50 34.86  ? 447  LYS B NZ  1 
ATOM   6954  N N   . ALA B 1 455 ? 38.322  -21.769 -20.156  1.00 31.30  ? 448  ALA B N   1 
ATOM   6955  C CA  . ALA B 1 455 ? 37.090  -22.163 -20.871  1.00 32.98  ? 448  ALA B CA  1 
ATOM   6956  C C   . ALA B 1 455 ? 37.443  -22.687 -22.275  1.00 35.35  ? 448  ALA B C   1 
ATOM   6957  O O   . ALA B 1 455 ? 36.984  -23.798 -22.643  1.00 37.55  ? 448  ALA B O   1 
ATOM   6958  C CB  . ALA B 1 455 ? 36.149  -20.986 -20.923  1.00 32.61  ? 448  ALA B CB  1 
ATOM   6959  N N   . LEU B 1 456 ? 38.240  -21.922 -23.028  1.00 34.51  ? 449  LEU B N   1 
ATOM   6960  C CA  . LEU B 1 456 ? 38.627  -22.247 -24.428  1.00 33.68  ? 449  LEU B CA  1 
ATOM   6961  C C   . LEU B 1 456 ? 39.455  -23.534 -24.456  1.00 34.23  ? 449  LEU B C   1 
ATOM   6962  O O   . LEU B 1 456 ? 39.211  -24.367 -25.332  1.00 32.51  ? 449  LEU B O   1 
ATOM   6963  C CB  . LEU B 1 456 ? 39.405  -21.069 -25.019  1.00 31.32  ? 449  LEU B CB  1 
ATOM   6964  C CG  . LEU B 1 456 ? 38.575  -19.812 -25.271  1.00 31.15  ? 449  LEU B CG  1 
ATOM   6965  C CD1 . LEU B 1 456 ? 39.443  -18.610 -25.581  1.00 29.62  ? 449  LEU B CD1 1 
ATOM   6966  C CD2 . LEU B 1 456 ? 37.576  -20.041 -26.397  1.00 32.75  ? 449  LEU B CD2 1 
ATOM   6967  N N   . ALA B 1 457 ? 40.388  -23.693 -23.513  1.00 38.32  ? 450  ALA B N   1 
ATOM   6968  C CA  . ALA B 1 457 ? 41.247  -24.892 -23.385  1.00 39.49  ? 450  ALA B CA  1 
ATOM   6969  C C   . ALA B 1 457 ? 40.379  -26.126 -23.143  1.00 42.92  ? 450  ALA B C   1 
ATOM   6970  O O   . ALA B 1 457 ? 40.654  -27.131 -23.780  1.00 46.43  ? 450  ALA B O   1 
ATOM   6971  C CB  . ALA B 1 457 ? 42.251  -24.699 -22.284  1.00 39.25  ? 450  ALA B CB  1 
ATOM   6972  N N   . ALA B 1 458 ? 39.373  -26.041 -22.263  1.00 44.40  ? 451  ALA B N   1 
ATOM   6973  C CA  . ALA B 1 458 ? 38.429  -27.144 -21.944  1.00 44.51  ? 451  ALA B CA  1 
ATOM   6974  C C   . ALA B 1 458 ? 37.614  -27.486 -23.191  1.00 44.66  ? 451  ALA B C   1 
ATOM   6975  O O   . ALA B 1 458 ? 37.446  -28.694 -23.467  1.00 47.82  ? 451  ALA B O   1 
ATOM   6976  C CB  . ALA B 1 458 ? 37.517  -26.767 -20.787  1.00 45.93  ? 451  ALA B CB  1 
ATOM   6977  N N   . MET B 1 459 ? 37.137  -26.462 -23.908  1.00 44.00  ? 452  MET B N   1 
ATOM   6978  C CA  . MET B 1 459 ? 36.349  -26.612 -25.155  1.00 42.64  ? 452  MET B CA  1 
ATOM   6979  C C   . MET B 1 459 ? 37.191  -27.350 -26.216  1.00 45.15  ? 452  MET B C   1 
ATOM   6980  O O   . MET B 1 459 ? 36.652  -28.260 -26.918  1.00 45.02  ? 452  MET B O   1 
ATOM   6981  C CB  . MET B 1 459 ? 35.926  -25.229 -25.675  1.00 43.18  ? 452  MET B CB  1 
ATOM   6982  C CG  . MET B 1 459 ? 34.806  -24.557 -24.874  1.00 42.74  ? 452  MET B CG  1 
ATOM   6983  S SD  . MET B 1 459 ? 34.673  -22.711 -25.057  1.00 39.13  ? 452  MET B SD  1 
ATOM   6984  C CE  . MET B 1 459 ? 34.257  -22.622 -26.795  1.00 36.70  ? 452  MET B CE  1 
ATOM   6985  N N   . ARG B 1 460 ? 38.469  -26.977 -26.353  1.00 46.27  ? 453  ARG B N   1 
ATOM   6986  C CA  . ARG B 1 460 ? 39.388  -27.593 -27.345  1.00 47.39  ? 453  ARG B CA  1 
ATOM   6987  C C   . ARG B 1 460 ? 39.515  -29.088 -27.044  1.00 48.06  ? 453  ARG B C   1 
ATOM   6988  O O   . ARG B 1 460 ? 39.397  -29.877 -27.984  1.00 47.74  ? 453  ARG B O   1 
ATOM   6989  C CB  . ARG B 1 460 ? 40.763  -26.913 -27.343  1.00 50.28  ? 453  ARG B CB  1 
ATOM   6990  C CG  . ARG B 1 460 ? 41.721  -27.517 -28.367  1.00 50.24  ? 453  ARG B CG  1 
ATOM   6991  C CD  . ARG B 1 460 ? 42.999  -26.750 -28.477  1.00 49.75  ? 453  ARG B CD  1 
ATOM   6992  N NE  . ARG B 1 460 ? 42.855  -25.602 -29.359  1.00 49.57  ? 453  ARG B NE  1 
ATOM   6993  C CZ  . ARG B 1 460 ? 43.736  -24.618 -29.440  1.00 46.10  ? 453  ARG B CZ  1 
ATOM   6994  N NH1 . ARG B 1 460 ? 44.824  -24.631 -28.684  1.00 45.02  ? 453  ARG B NH1 1 
ATOM   6995  N NH2 . ARG B 1 460 ? 43.520  -23.619 -30.269  1.00 44.14  ? 453  ARG B NH2 1 
ATOM   6996  N N   . VAL B 1 461 ? 39.726  -29.450 -25.776  1.00 51.33  ? 454  VAL B N   1 
ATOM   6997  C CA  . VAL B 1 461 ? 39.849  -30.860 -25.297  1.00 58.52  ? 454  VAL B CA  1 
ATOM   6998  C C   . VAL B 1 461 ? 38.581  -31.616 -25.700  1.00 61.19  ? 454  VAL B C   1 
ATOM   6999  O O   . VAL B 1 461 ? 38.732  -32.652 -26.357  1.00 69.58  ? 454  VAL B O   1 
ATOM   7000  C CB  . VAL B 1 461 ? 40.124  -30.927 -23.778  1.00 65.14  ? 454  VAL B CB  1 
ATOM   7001  C CG1 . VAL B 1 461 ? 39.907  -32.312 -23.194  1.00 68.79  ? 454  VAL B CG1 1 
ATOM   7002  C CG2 . VAL B 1 461 ? 41.534  -30.449 -23.447  1.00 61.58  ? 454  VAL B CG2 1 
ATOM   7003  N N   . SER B 1 462 ? 37.391  -31.101 -25.371  1.00 66.50  ? 455  SER B N   1 
ATOM   7004  C CA  . SER B 1 462 ? 36.077  -31.695 -25.753  1.00 73.45  ? 455  SER B CA  1 
ATOM   7005  C C   . SER B 1 462 ? 36.104  -32.070 -27.240  1.00 77.36  ? 455  SER B C   1 
ATOM   7006  O O   . SER B 1 462 ? 35.884  -33.269 -27.573  1.00 94.12  ? 455  SER B O   1 
ATOM   7007  C CB  . SER B 1 462 ? 34.930  -30.760 -25.459  1.00 75.65  ? 455  SER B CB  1 
ATOM   7008  O OG  . SER B 1 462 ? 35.013  -30.215 -24.147  1.00 75.20  ? 455  SER B OG  1 
ATOM   7009  N N   . VAL B 1 463 ? 36.396  -31.087 -28.096  1.00 74.30  ? 456  VAL B N   1 
ATOM   7010  C CA  . VAL B 1 463 ? 36.475  -31.255 -29.577  1.00 71.59  ? 456  VAL B CA  1 
ATOM   7011  C C   . VAL B 1 463 ? 37.499  -32.361 -29.888  1.00 76.23  ? 456  VAL B C   1 
ATOM   7012  O O   . VAL B 1 463 ? 37.072  -33.407 -30.400  1.00 84.53  ? 456  VAL B O   1 
ATOM   7013  C CB  . VAL B 1 463 ? 36.797  -29.910 -30.258  1.00 64.30  ? 456  VAL B CB  1 
ATOM   7014  C CG1 . VAL B 1 463 ? 37.195  -30.072 -31.711  1.00 64.44  ? 456  VAL B CG1 1 
ATOM   7015  C CG2 . VAL B 1 463 ? 35.639  -28.936 -30.127  1.00 61.18  ? 456  VAL B CG2 1 
ATOM   7016  N N   . GLU B 1 464 ? 38.778  -32.153 -29.559  1.00 80.07  ? 457  GLU B N   1 
ATOM   7017  C CA  . GLU B 1 464 ? 39.899  -33.117 -29.778  1.00 84.34  ? 457  GLU B CA  1 
ATOM   7018  C C   . GLU B 1 464 ? 39.501  -34.533 -29.325  1.00 90.20  ? 457  GLU B C   1 
ATOM   7019  O O   . GLU B 1 464 ? 39.763  -35.456 -30.089  1.00 98.51  ? 457  GLU B O   1 
ATOM   7020  C CB  . GLU B 1 464 ? 41.169  -32.657 -29.055  1.00 82.97  ? 457  GLU B CB  1 
ATOM   7021  C CG  . GLU B 1 464 ? 41.798  -31.421 -29.669  1.00 83.81  ? 457  GLU B CG  1 
ATOM   7022  C CD  . GLU B 1 464 ? 42.993  -30.847 -28.921  1.00 86.45  ? 457  GLU B CD  1 
ATOM   7023  O OE1 . GLU B 1 464 ? 43.095  -31.056 -27.695  1.00 89.98  ? 457  GLU B OE1 1 
ATOM   7024  O OE2 . GLU B 1 464 ? 43.847  -30.217 -29.572  1.00 84.00  ? 457  GLU B OE2 1 
ATOM   7025  N N   . GLU B 1 465 ? 38.887  -34.690 -28.149  1.00 93.31  ? 458  GLU B N   1 
ATOM   7026  C CA  . GLU B 1 465 ? 38.400  -36.001 -27.612  1.00 97.47  ? 458  GLU B CA  1 
ATOM   7027  C C   . GLU B 1 465 ? 37.425  -36.662 -28.596  1.00 100.31 ? 458  GLU B C   1 
ATOM   7028  O O   . GLU B 1 465 ? 37.749  -37.760 -29.051  1.00 105.33 ? 458  GLU B O   1 
ATOM   7029  C CB  . GLU B 1 465 ? 37.698  -35.845 -26.264  1.00 102.47 ? 458  GLU B CB  1 
ATOM   7030  C CG  . GLU B 1 465 ? 38.638  -35.598 -25.102  1.00 98.86  ? 458  GLU B CG  1 
ATOM   7031  C CD  . GLU B 1 465 ? 37.926  -35.378 -23.777  1.00 100.70 ? 458  GLU B CD  1 
ATOM   7032  O OE1 . GLU B 1 465 ? 36.668  -35.261 -23.760  1.00 98.85  ? 458  GLU B OE1 1 
ATOM   7033  O OE2 . GLU B 1 465 ? 38.629  -35.327 -22.759  1.00 92.69  ? 458  GLU B OE2 1 
ATOM   7034  N N   . ALA B 1 466 ? 36.250  -36.057 -28.832  1.00 104.18 ? 459  ALA B N   1 
ATOM   7035  C CA  . ALA B 1 466 ? 35.271  -36.410 -29.895  1.00 104.67 ? 459  ALA B CA  1 
ATOM   7036  C C   . ALA B 1 466 ? 35.997  -36.988 -31.121  1.00 107.58 ? 459  ALA B C   1 
ATOM   7037  O O   . ALA B 1 466 ? 35.719  -38.146 -31.493  1.00 112.76 ? 459  ALA B O   1 
ATOM   7038  C CB  . ALA B 1 466 ? 34.462  -35.186 -30.277  1.00 97.43  ? 459  ALA B CB  1 
ATOM   7039  N N   . LEU B 1 467 ? 36.900  -36.211 -31.722  1.00 106.35 ? 460  LEU B N   1 
ATOM   7040  C CA  . LEU B 1 467 ? 37.646  -36.550 -32.974  1.00 109.75 ? 460  LEU B CA  1 
ATOM   7041  C C   . LEU B 1 467 ? 38.407  -37.882 -32.797  1.00 105.37 ? 460  LEU B C   1 
ATOM   7042  O O   . LEU B 1 467 ? 38.292  -38.751 -33.687  1.00 108.36 ? 460  LEU B O   1 
ATOM   7043  C CB  . LEU B 1 467 ? 38.615  -35.419 -33.349  1.00 107.79 ? 460  LEU B CB  1 
ATOM   7044  C CG  . LEU B 1 467 ? 38.076  -33.988 -33.301  1.00 110.70 ? 460  LEU B CG  1 
ATOM   7045  C CD1 . LEU B 1 467 ? 38.986  -33.058 -34.081  1.00 108.19 ? 460  LEU B CD1 1 
ATOM   7046  C CD2 . LEU B 1 467 ? 36.638  -33.904 -33.813  1.00 106.96 ? 460  LEU B CD2 1 
ATOM   7047  N N   . GLU B 1 468 ? 39.159  -38.027 -31.698  1.00 101.49 ? 461  GLU B N   1 
ATOM   7048  C CA  . GLU B 1 468 ? 39.931  -39.249 -31.349  1.00 107.91 ? 461  GLU B CA  1 
ATOM   7049  C C   . GLU B 1 468 ? 38.972  -40.441 -31.328  1.00 115.52 ? 461  GLU B C   1 
ATOM   7050  O O   . GLU B 1 468 ? 39.199  -41.385 -32.111  1.00 128.88 ? 461  GLU B O   1 
ATOM   7051  C CB  . GLU B 1 468 ? 40.640  -39.108 -29.998  1.00 109.11 ? 461  GLU B CB  1 
ATOM   7052  C CG  . GLU B 1 468 ? 41.526  -40.293 -29.656  1.00 113.97 ? 461  GLU B CG  1 
ATOM   7053  C CD  . GLU B 1 468 ? 42.443  -40.762 -30.781  1.00 125.19 ? 461  GLU B CD  1 
ATOM   7054  O OE1 . GLU B 1 468 ? 43.667  -40.551 -30.678  1.00 123.04 ? 461  GLU B OE1 1 
ATOM   7055  O OE2 . GLU B 1 468 ? 41.936  -41.331 -31.768  1.00 140.11 ? 461  GLU B OE2 1 
ATOM   7056  N N   . VAL B 1 469 ? 37.909  -40.365 -30.514  1.00 120.31 ? 462  VAL B N   1 
ATOM   7057  C CA  . VAL B 1 469 ? 36.827  -41.398 -30.406  1.00 119.55 ? 462  VAL B CA  1 
ATOM   7058  C C   . VAL B 1 469 ? 36.367  -41.798 -31.826  1.00 120.46 ? 462  VAL B C   1 
ATOM   7059  O O   . VAL B 1 469 ? 36.464  -43.007 -32.140  1.00 123.04 ? 462  VAL B O   1 
ATOM   7060  C CB  . VAL B 1 469 ? 35.663  -40.915 -29.504  1.00 116.24 ? 462  VAL B CB  1 
ATOM   7061  C CG1 . VAL B 1 469 ? 34.628  -42.000 -29.227  1.00 111.31 ? 462  VAL B CG1 1 
ATOM   7062  C CG2 . VAL B 1 469 ? 36.163  -40.329 -28.186  1.00 112.80 ? 462  VAL B CG2 1 
ATOM   7063  N N   . SER B 1 470 ? 36.019  -40.830 -32.688  1.00 114.44 ? 463  SER B N   1 
ATOM   7064  C CA  . SER B 1 470 ? 35.503  -41.078 -34.066  1.00 109.00 ? 463  SER B CA  1 
ATOM   7065  C C   . SER B 1 470 ? 36.508  -41.914 -34.880  1.00 114.15 ? 463  SER B C   1 
ATOM   7066  O O   . SER B 1 470 ? 36.123  -43.022 -35.340  1.00 126.10 ? 463  SER B O   1 
ATOM   7067  C CB  . SER B 1 470 ? 35.169  -39.787 -34.772  1.00 99.01  ? 463  SER B CB  1 
ATOM   7068  O OG  . SER B 1 470 ? 34.452  -38.909 -33.921  1.00 93.60  ? 463  SER B OG  1 
ATOM   7069  N N   . ALA B 1 471 ? 37.735  -41.401 -35.061  1.00 114.98 ? 464  ALA B N   1 
ATOM   7070  C CA  . ALA B 1 471 ? 38.833  -42.013 -35.854  1.00 111.48 ? 464  ALA B CA  1 
ATOM   7071  C C   . ALA B 1 471 ? 39.051  -43.474 -35.439  1.00 119.89 ? 464  ALA B C   1 
ATOM   7072  O O   . ALA B 1 471 ? 39.139  -44.321 -36.354  1.00 118.40 ? 464  ALA B O   1 
ATOM   7073  C CB  . ALA B 1 471 ? 40.109  -41.225 -35.703  1.00 103.11 ? 464  ALA B CB  1 
ATOM   7074  N N   . LYS B 1 472 ? 39.223  -43.745 -34.136  1.00 128.25 ? 465  LYS B N   1 
ATOM   7075  C CA  . LYS B 1 472 ? 39.534  -45.106 -33.603  1.00 128.03 ? 465  LYS B CA  1 
ATOM   7076  C C   . LYS B 1 472 ? 38.380  -46.047 -33.963  1.00 132.07 ? 465  LYS B C   1 
ATOM   7077  O O   . LYS B 1 472 ? 38.666  -47.145 -34.510  1.00 149.46 ? 465  LYS B O   1 
ATOM   7078  C CB  . LYS B 1 472 ? 39.817  -45.089 -32.095  1.00 121.81 ? 465  LYS B CB  1 
ATOM   7079  C CG  . LYS B 1 472 ? 41.074  -44.325 -31.675  1.00 129.56 ? 465  LYS B CG  1 
ATOM   7080  C CD  . LYS B 1 472 ? 42.372  -44.848 -32.294  1.00 132.98 ? 465  LYS B CD  1 
ATOM   7081  C CE  . LYS B 1 472 ? 43.592  -43.983 -32.047  1.00 126.63 ? 465  LYS B CE  1 
ATOM   7082  N NZ  . LYS B 1 472 ? 44.046  -44.086 -30.643  1.00 125.04 ? 465  LYS B NZ  1 
ATOM   7083  N N   . GLU B 1 473 ? 37.135  -45.657 -33.653  1.00 125.43 ? 466  GLU B N   1 
ATOM   7084  C CA  . GLU B 1 473 ? 35.909  -46.440 -34.001  1.00 124.75 ? 466  GLU B CA  1 
ATOM   7085  C C   . GLU B 1 473 ? 36.004  -46.855 -35.482  1.00 133.85 ? 466  GLU B C   1 
ATOM   7086  O O   . GLU B 1 473 ? 35.799  -48.067 -35.795  1.00 133.57 ? 466  GLU B O   1 
ATOM   7087  C CB  . GLU B 1 473 ? 34.642  -45.617 -33.688  1.00 117.89 ? 466  GLU B CB  1 
ATOM   7088  C CG  . GLU B 1 473 ? 33.546  -45.636 -34.765  1.00 113.97 ? 466  GLU B CG  1 
ATOM   7089  C CD  . GLU B 1 473 ? 32.885  -44.300 -35.091  1.00 105.59 ? 466  GLU B CD  1 
ATOM   7090  O OE1 . GLU B 1 473 ? 32.501  -43.592 -34.137  1.00 93.69  ? 466  GLU B OE1 1 
ATOM   7091  O OE2 . GLU B 1 473 ? 32.774  -43.964 -36.301  1.00 88.88  ? 466  GLU B OE2 1 
ATOM   7092  N N   . GLN B 1 474 ? 36.350  -45.893 -36.352  1.00 135.97 ? 467  GLN B N   1 
ATOM   7093  C CA  . GLN B 1 474 ? 36.450  -46.070 -37.829  1.00 126.51 ? 467  GLN B CA  1 
ATOM   7094  C C   . GLN B 1 474 ? 37.564  -47.074 -38.173  1.00 130.91 ? 467  GLN B C   1 
ATOM   7095  O O   . GLN B 1 474 ? 37.258  -48.089 -38.858  1.00 143.17 ? 467  GLN B O   1 
ATOM   7096  C CB  . GLN B 1 474 ? 36.663  -44.715 -38.504  1.00 116.13 ? 467  GLN B CB  1 
ATOM   7097  C CG  . GLN B 1 474 ? 35.428  -43.824 -38.459  1.00 109.35 ? 467  GLN B CG  1 
ATOM   7098  C CD  . GLN B 1 474 ? 35.274  -42.983 -39.702  1.00 104.29 ? 467  GLN B CD  1 
ATOM   7099  O OE1 . GLN B 1 474 ? 36.248  -42.683 -40.389  1.00 88.93  ? 467  GLN B OE1 1 
ATOM   7100  N NE2 . GLN B 1 474 ? 34.039  -42.606 -40.004  1.00 102.23 ? 467  GLN B NE2 1 
ATOM   7101  N N   . GLN B 1 475 ? 38.796  -46.820 -37.711  1.00 125.21 ? 468  GLN B N   1 
ATOM   7102  C CA  . GLN B 1 475 ? 39.977  -47.715 -37.889  1.00 122.93 ? 468  GLN B CA  1 
ATOM   7103  C C   . GLN B 1 475 ? 39.625  -49.131 -37.408  1.00 129.76 ? 468  GLN B C   1 
ATOM   7104  O O   . GLN B 1 475 ? 40.032  -50.111 -38.085  1.00 130.83 ? 468  GLN B O   1 
ATOM   7105  C CB  . GLN B 1 475 ? 41.175  -47.142 -37.122  1.00 119.13 ? 468  GLN B CB  1 
ATOM   7106  C CG  . GLN B 1 475 ? 42.289  -48.139 -36.829  1.00 117.49 ? 468  GLN B CG  1 
ATOM   7107  C CD  . GLN B 1 475 ? 42.896  -47.937 -35.460  1.00 119.20 ? 468  GLN B CD  1 
ATOM   7108  O OE1 . GLN B 1 475 ? 42.195  -47.881 -34.454  1.00 118.38 ? 468  GLN B OE1 1 
ATOM   7109  N NE2 . GLN B 1 475 ? 44.213  -47.845 -35.408  1.00 120.92 ? 468  GLN B NE2 1 
ATOM   7110  N N   . ASN B 1 476 ? 38.913  -49.225 -36.279  1.00 134.00 ? 469  ASN B N   1 
ATOM   7111  C CA  . ASN B 1 476 ? 38.561  -50.507 -35.610  1.00 133.30 ? 469  ASN B CA  1 
ATOM   7112  C C   . ASN B 1 476 ? 37.743  -51.380 -36.573  1.00 138.64 ? 469  ASN B C   1 
ATOM   7113  O O   . ASN B 1 476 ? 38.082  -52.577 -36.690  1.00 153.47 ? 469  ASN B O   1 
ATOM   7114  C CB  . ASN B 1 476 ? 37.845  -50.278 -34.276  1.00 130.04 ? 469  ASN B CB  1 
ATOM   7115  C CG  . ASN B 1 476 ? 37.895  -51.497 -33.380  1.00 123.77 ? 469  ASN B CG  1 
ATOM   7116  O OD1 . ASN B 1 476 ? 38.913  -52.181 -33.301  1.00 116.29 ? 469  ASN B OD1 1 
ATOM   7117  N ND2 . ASN B 1 476 ? 36.807  -51.766 -32.681  1.00 118.56 ? 469  ASN B ND2 1 
ATOM   7118  N N   . ALA B 1 477 ? 36.736  -50.803 -37.247  1.00 125.45 ? 470  ALA B N   1 
ATOM   7119  C CA  . ALA B 1 477 ? 35.867  -51.457 -38.261  1.00 111.67 ? 470  ALA B CA  1 
ATOM   7120  C C   . ALA B 1 477 ? 36.419  -52.836 -38.657  1.00 110.18 ? 470  ALA B C   1 
ATOM   7121  O O   . ALA B 1 477 ? 37.408  -52.967 -39.392  1.00 106.77 ? 470  ALA B O   1 
ATOM   7122  C CB  . ALA B 1 477 ? 35.728  -50.566 -39.471  1.00 103.52 ? 470  ALA B CB  1 
ATOM   7123  N N   . ALA C 1 15  ? -26.742 26.096  -73.542  1.00 87.75  ? 8    ALA C N   1 
ATOM   7124  C CA  . ALA C 1 15  ? -27.764 25.289  -74.271  1.00 82.43  ? 8    ALA C CA  1 
ATOM   7125  C C   . ALA C 1 15  ? -28.120 24.033  -73.458  1.00 72.61  ? 8    ALA C C   1 
ATOM   7126  O O   . ALA C 1 15  ? -27.432 23.741  -72.441  1.00 59.94  ? 8    ALA C O   1 
ATOM   7127  C CB  . ALA C 1 15  ? -27.242 24.945  -75.648  1.00 80.59  ? 8    ALA C CB  1 
ATOM   7128  N N   . SER C 1 16  ? -29.164 23.315  -73.887  1.00 60.83  ? 9    SER C N   1 
ATOM   7129  C CA  . SER C 1 16  ? -29.488 21.957  -73.385  1.00 52.37  ? 9    SER C CA  1 
ATOM   7130  C C   . SER C 1 16  ? -28.361 21.001  -73.797  1.00 47.04  ? 9    SER C C   1 
ATOM   7131  O O   . SER C 1 16  ? -27.601 21.325  -74.733  1.00 44.49  ? 9    SER C O   1 
ATOM   7132  C CB  . SER C 1 16  ? -30.844 21.487  -73.872  1.00 51.98  ? 9    SER C CB  1 
ATOM   7133  O OG  . SER C 1 16  ? -30.807 21.100  -75.241  1.00 48.45  ? 9    SER C OG  1 
ATOM   7134  N N   . ALA C 1 17  ? -28.238 19.876  -73.102  1.00 41.29  ? 10   ALA C N   1 
ATOM   7135  C CA  . ALA C 1 17  ? -27.338 18.764  -73.482  1.00 38.36  ? 10   ALA C CA  1 
ATOM   7136  C C   . ALA C 1 17  ? -27.703 18.260  -74.882  1.00 34.17  ? 10   ALA C C   1 
ATOM   7137  O O   . ALA C 1 17  ? -26.795 17.988  -75.662  1.00 35.95  ? 10   ALA C O   1 
ATOM   7138  C CB  . ALA C 1 17  ? -27.419 17.656  -72.463  1.00 38.04  ? 10   ALA C CB  1 
ATOM   7139  N N   . LEU C 1 18  ? -28.989 18.129  -75.182  1.00 33.14  ? 11   LEU C N   1 
ATOM   7140  C CA  . LEU C 1 18  ? -29.460 17.602  -76.487  1.00 32.84  ? 11   LEU C CA  1 
ATOM   7141  C C   . LEU C 1 18  ? -28.879 18.466  -77.610  1.00 32.82  ? 11   LEU C C   1 
ATOM   7142  O O   . LEU C 1 18  ? -28.357 17.905  -78.584  1.00 30.83  ? 11   LEU C O   1 
ATOM   7143  C CB  . LEU C 1 18  ? -30.995 17.612  -76.535  1.00 31.79  ? 11   LEU C CB  1 
ATOM   7144  C CG  . LEU C 1 18  ? -31.576 17.041  -77.829  1.00 31.13  ? 11   LEU C CG  1 
ATOM   7145  C CD1 . LEU C 1 18  ? -30.950 15.691  -78.121  1.00 33.20  ? 11   LEU C CD1 1 
ATOM   7146  C CD2 . LEU C 1 18  ? -33.083 16.934  -77.821  1.00 29.48  ? 11   LEU C CD2 1 
ATOM   7147  N N   . ALA C 1 19  ? -28.973 19.787  -77.449  1.00 34.84  ? 12   ALA C N   1 
ATOM   7148  C CA  . ALA C 1 19  ? -28.502 20.822  -78.392  1.00 36.52  ? 12   ALA C CA  1 
ATOM   7149  C C   . ALA C 1 19  ? -26.991 20.699  -78.613  1.00 39.51  ? 12   ALA C C   1 
ATOM   7150  O O   . ALA C 1 19  ? -26.576 20.771  -79.776  1.00 47.68  ? 12   ALA C O   1 
ATOM   7151  C CB  . ALA C 1 19  ? -28.865 22.183  -77.863  1.00 37.29  ? 12   ALA C CB  1 
ATOM   7152  N N   . CYS C 1 20  ? -26.206 20.539  -77.545  1.00 41.25  ? 13   CYS C N   1 
ATOM   7153  C CA  . CYS C 1 20  ? -24.730 20.393  -77.614  1.00 44.40  ? 13   CYS C CA  1 
ATOM   7154  C C   . CYS C 1 20  ? -24.375 19.031  -78.224  1.00 40.63  ? 13   CYS C C   1 
ATOM   7155  O O   . CYS C 1 20  ? -23.461 19.016  -79.074  1.00 37.71  ? 13   CYS C O   1 
ATOM   7156  C CB  . CYS C 1 20  ? -24.062 20.570  -76.255  1.00 50.61  ? 13   CYS C CB  1 
ATOM   7157  S SG  . CYS C 1 20  ? -24.323 22.210  -75.529  1.00 58.11  ? 13   CYS C SG  1 
ATOM   7158  N N   . SER C 1 21  ? -25.075 17.944  -77.859  1.00 34.19  ? 14   SER C N   1 
ATOM   7159  C CA  . SER C 1 21  ? -24.801 16.588  -78.416  1.00 32.84  ? 14   SER C CA  1 
ATOM   7160  C C   . SER C 1 21  ? -25.087 16.588  -79.928  1.00 31.68  ? 14   SER C C   1 
ATOM   7161  O O   . SER C 1 21  ? -24.365 15.921  -80.675  1.00 32.35  ? 14   SER C O   1 
ATOM   7162  C CB  . SER C 1 21  ? -25.550 15.501  -77.680  1.00 30.07  ? 14   SER C CB  1 
ATOM   7163  O OG  . SER C 1 21  ? -26.925 15.483  -78.036  1.00 31.76  ? 14   SER C OG  1 
ATOM   7164  N N   . ALA C 1 22  ? -26.076 17.369  -80.359  1.00 33.51  ? 15   ALA C N   1 
ATOM   7165  C CA  . ALA C 1 22  ? -26.480 17.548  -81.772  1.00 34.29  ? 15   ALA C CA  1 
ATOM   7166  C C   . ALA C 1 22  ? -25.401 18.336  -82.518  1.00 36.56  ? 15   ALA C C   1 
ATOM   7167  O O   . ALA C 1 22  ? -24.934 17.840  -83.548  1.00 34.83  ? 15   ALA C O   1 
ATOM   7168  C CB  . ALA C 1 22  ? -27.820 18.247  -81.846  1.00 34.34  ? 15   ALA C CB  1 
ATOM   7169  N N   . HIS C 1 23  ? -25.029 19.516  -82.011  1.00 38.15  ? 16   HIS C N   1 
ATOM   7170  C CA  . HIS C 1 23  ? -24.026 20.428  -82.620  1.00 39.10  ? 16   HIS C CA  1 
ATOM   7171  C C   . HIS C 1 23  ? -22.730 19.649  -82.857  1.00 38.36  ? 16   HIS C C   1 
ATOM   7172  O O   . HIS C 1 23  ? -22.049 19.890  -83.879  1.00 40.08  ? 16   HIS C O   1 
ATOM   7173  C CB  . HIS C 1 23  ? -23.821 21.658  -81.728  1.00 40.91  ? 16   HIS C CB  1 
ATOM   7174  C CG  . HIS C 1 23  ? -22.691 22.512  -82.179  1.00 45.74  ? 16   HIS C CG  1 
ATOM   7175  N ND1 . HIS C 1 23  ? -22.755 23.256  -83.340  1.00 49.93  ? 16   HIS C ND1 1 
ATOM   7176  C CD2 . HIS C 1 23  ? -21.458 22.708  -81.662  1.00 49.54  ? 16   HIS C CD2 1 
ATOM   7177  C CE1 . HIS C 1 23  ? -21.607 23.881  -83.516  1.00 54.69  ? 16   HIS C CE1 1 
ATOM   7178  N NE2 . HIS C 1 23  ? -20.793 23.566  -82.491  1.00 53.83  ? 16   HIS C NE2 1 
ATOM   7179  N N   . ALA C 1 24  ? -22.426 18.729  -81.945  1.00 38.10  ? 17   ALA C N   1 
ATOM   7180  C CA  . ALA C 1 24  ? -21.164 17.965  -81.920  1.00 39.36  ? 17   ALA C CA  1 
ATOM   7181  C C   . ALA C 1 24  ? -21.241 16.823  -82.923  1.00 37.11  ? 17   ALA C C   1 
ATOM   7182  O O   . ALA C 1 24  ? -20.242 16.591  -83.602  1.00 42.49  ? 17   ALA C O   1 
ATOM   7183  C CB  . ALA C 1 24  ? -20.891 17.446  -80.529  1.00 42.63  ? 17   ALA C CB  1 
ATOM   7184  N N   . LEU C 1 25  ? -22.362 16.112  -82.999  1.00 34.87  ? 18   LEU C N   1 
ATOM   7185  C CA  . LEU C 1 25  ? -22.511 15.043  -84.022  1.00 36.49  ? 18   LEU C CA  1 
ATOM   7186  C C   . LEU C 1 25  ? -22.426 15.646  -85.433  1.00 36.27  ? 18   LEU C C   1 
ATOM   7187  O O   . LEU C 1 25  ? -21.862 14.992  -86.317  1.00 34.66  ? 18   LEU C O   1 
ATOM   7188  C CB  . LEU C 1 25  ? -23.831 14.308  -83.799  1.00 37.72  ? 18   LEU C CB  1 
ATOM   7189  C CG  . LEU C 1 25  ? -23.875 13.462  -82.536  1.00 39.06  ? 18   LEU C CG  1 
ATOM   7190  C CD1 . LEU C 1 25  ? -25.288 12.953  -82.284  1.00 42.69  ? 18   LEU C CD1 1 
ATOM   7191  C CD2 . LEU C 1 25  ? -22.890 12.313  -82.638  1.00 38.46  ? 18   LEU C CD2 1 
ATOM   7192  N N   A ASN C 1 26  ? -22.978 16.856  -85.615  0.49 37.90  ? 19   ASN C N   1 
ATOM   7193  N N   B ASN C 1 26  ? -22.964 16.854  -85.615  0.51 36.64  ? 19   ASN C N   1 
ATOM   7194  C CA  A ASN C 1 26  ? -22.899 17.669  -86.861  0.49 39.52  ? 19   ASN C CA  1 
ATOM   7195  C CA  B ASN C 1 26  ? -22.900 17.588  -86.904  0.51 37.52  ? 19   ASN C CA  1 
ATOM   7196  C C   A ASN C 1 26  ? -21.428 17.903  -87.195  0.49 38.73  ? 19   ASN C C   1 
ATOM   7197  C C   B ASN C 1 26  ? -21.430 17.908  -87.201  0.51 37.56  ? 19   ASN C C   1 
ATOM   7198  O O   A ASN C 1 26  ? -21.052 17.723  -88.363  0.49 39.84  ? 19   ASN C O   1 
ATOM   7199  O O   B ASN C 1 26  ? -21.045 17.727  -88.363  0.51 38.75  ? 19   ASN C O   1 
ATOM   7200  C CB  A ASN C 1 26  ? -23.625 19.015  -86.726  0.49 41.05  ? 19   ASN C CB  1 
ATOM   7201  C CB  B ASN C 1 26  ? -23.866 18.777  -86.939  0.51 37.38  ? 19   ASN C CB  1 
ATOM   7202  C CG  A ASN C 1 26  ? -23.539 19.902  -87.952  0.49 40.85  ? 19   ASN C CG  1 
ATOM   7203  C CG  B ASN C 1 26  ? -25.320 18.350  -87.040  0.51 36.13  ? 19   ASN C CG  1 
ATOM   7204  O OD1 A ASN C 1 26  ? -22.880 20.937  -87.931  0.49 40.84  ? 19   ASN C OD1 1 
ATOM   7205  O OD1 B ASN C 1 26  ? -25.651 17.328  -87.644  0.51 34.13  ? 19   ASN C OD1 1 
ATOM   7206  N ND2 A ASN C 1 26  ? -24.250 19.542  -89.009  0.49 41.57  ? 19   ASN C ND2 1 
ATOM   7207  N ND2 B ASN C 1 26  ? -26.204 19.132  -86.443  0.51 36.08  ? 19   ASN C ND2 1 
ATOM   7208  N N   . LEU C 1 27  ? -20.632 18.287  -86.195  1.00 37.31  ? 20   LEU C N   1 
ATOM   7209  C CA  . LEU C 1 27  ? -19.180 18.560  -86.363  1.00 37.42  ? 20   LEU C CA  1 
ATOM   7210  C C   . LEU C 1 27  ? -18.421 17.272  -86.713  1.00 35.46  ? 20   LEU C C   1 
ATOM   7211  O O   . LEU C 1 27  ? -17.527 17.347  -87.563  1.00 35.86  ? 20   LEU C O   1 
ATOM   7212  C CB  . LEU C 1 27  ? -18.665 19.204  -85.081  1.00 39.58  ? 20   LEU C CB  1 
ATOM   7213  C CG  . LEU C 1 27  ? -17.181 19.530  -85.076  1.00 43.91  ? 20   LEU C CG  1 
ATOM   7214  C CD1 . LEU C 1 27  ? -16.867 20.737  -85.945  1.00 46.36  ? 20   LEU C CD1 1 
ATOM   7215  C CD2 . LEU C 1 27  ? -16.722 19.775  -83.654  1.00 49.50  ? 20   LEU C CD2 1 
ATOM   7216  N N   . ILE C 1 28  ? -18.794 16.131  -86.130  1.00 35.11  ? 21   ILE C N   1 
ATOM   7217  C CA  . ILE C 1 28  ? -18.145 14.809  -86.396  1.00 34.97  ? 21   ILE C CA  1 
ATOM   7218  C C   . ILE C 1 28  ? -18.328 14.411  -87.872  1.00 35.15  ? 21   ILE C C   1 
ATOM   7219  O O   . ILE C 1 28  ? -17.397 13.801  -88.427  1.00 35.12  ? 21   ILE C O   1 
ATOM   7220  C CB  . ILE C 1 28  ? -18.666 13.733  -85.424  1.00 32.23  ? 21   ILE C CB  1 
ATOM   7221  C CG1 . ILE C 1 28  ? -18.191 14.023  -84.000  1.00 32.12  ? 21   ILE C CG1 1 
ATOM   7222  C CG2 . ILE C 1 28  ? -18.260 12.336  -85.871  1.00 30.63  ? 21   ILE C CG2 1 
ATOM   7223  C CD1 . ILE C 1 28  ? -18.865 13.189  -82.935  1.00 31.50  ? 21   ILE C CD1 1 
ATOM   7224  N N   . GLU C 1 29  ? -19.472 14.736  -88.481  1.00 37.08  ? 22   GLU C N   1 
ATOM   7225  C CA  . GLU C 1 29  ? -19.786 14.405  -89.896  1.00 40.96  ? 22   GLU C CA  1 
ATOM   7226  C C   . GLU C 1 29  ? -18.956 15.263  -90.858  1.00 42.24  ? 22   GLU C C   1 
ATOM   7227  O O   . GLU C 1 29  ? -18.518 14.714  -91.867  1.00 41.67  ? 22   GLU C O   1 
ATOM   7228  C CB  . GLU C 1 29  ? -21.256 14.653  -90.225  1.00 44.71  ? 22   GLU C CB  1 
ATOM   7229  C CG  . GLU C 1 29  ? -22.240 13.844  -89.410  1.00 45.88  ? 22   GLU C CG  1 
ATOM   7230  C CD  . GLU C 1 29  ? -23.700 14.102  -89.778  1.00 49.35  ? 22   GLU C CD  1 
ATOM   7231  O OE1 . GLU C 1 29  ? -23.994 14.157  -91.000  1.00 50.28  ? 22   GLU C OE1 1 
ATOM   7232  O OE2 . GLU C 1 29  ? -24.549 14.265  -88.844  1.00 44.72  ? 22   GLU C OE2 1 
ATOM   7233  N N   . LYS C 1 30  ? -18.808 16.561  -90.570  1.00 44.36  ? 23   LYS C N   1 
ATOM   7234  C CA  . LYS C 1 30  ? -18.058 17.548  -91.396  1.00 46.74  ? 23   LYS C CA  1 
ATOM   7235  C C   . LYS C 1 30  ? -16.629 17.034  -91.595  1.00 47.99  ? 23   LYS C C   1 
ATOM   7236  O O   . LYS C 1 30  ? -16.043 16.527  -90.614  1.00 45.89  ? 23   LYS C O   1 
ATOM   7237  C CB  . LYS C 1 30  ? -18.078 18.923  -90.715  1.00 47.73  ? 23   LYS C CB  1 
ATOM   7238  C CG  . LYS C 1 30  ? -19.430 19.636  -90.733  1.00 52.43  ? 23   LYS C CG  1 
ATOM   7239  C CD  . LYS C 1 30  ? -19.499 20.974  -89.985  1.00 54.57  ? 23   LYS C CD  1 
ATOM   7240  C CE  . LYS C 1 30  ? -18.681 22.089  -90.605  1.00 58.19  ? 23   LYS C CE  1 
ATOM   7241  N NZ  . LYS C 1 30  ? -18.673 22.055  -92.094  1.00 63.46  ? 23   LYS C NZ  1 
ATOM   7242  N N   A ARG C 1 31  ? -16.103 17.122  -92.824  0.50 48.39  ? 24   ARG C N   1 
ATOM   7243  N N   B ARG C 1 31  ? -16.107 17.123  -92.825  0.50 47.37  ? 24   ARG C N   1 
ATOM   7244  C CA  A ARG C 1 31  ? -14.706 16.710  -93.147  0.50 50.55  ? 24   ARG C CA  1 
ATOM   7245  C CA  B ARG C 1 31  ? -14.715 16.711  -93.163  0.50 48.81  ? 24   ARG C CA  1 
ATOM   7246  C C   A ARG C 1 31  ? -13.815 17.947  -93.314  0.50 49.46  ? 24   ARG C C   1 
ATOM   7247  C C   B ARG C 1 31  ? -13.818 17.945  -93.321  0.50 48.48  ? 24   ARG C C   1 
ATOM   7248  O O   A ARG C 1 31  ? -12.594 17.799  -93.243  0.50 48.49  ? 24   ARG C O   1 
ATOM   7249  O O   B ARG C 1 31  ? -12.587 17.799  -93.251  0.50 47.64  ? 24   ARG C O   1 
ATOM   7250  C CB  A ARG C 1 31  ? -14.648 15.873  -94.427  0.50 53.94  ? 24   ARG C CB  1 
ATOM   7251  C CB  B ARG C 1 31  ? -14.704 15.880  -94.447  0.50 50.73  ? 24   ARG C CB  1 
ATOM   7252  C CG  A ARG C 1 31  ? -15.357 14.528  -94.367  0.50 56.38  ? 24   ARG C CG  1 
ATOM   7253  C CG  B ARG C 1 31  ? -15.194 14.450  -94.271  0.50 51.84  ? 24   ARG C CG  1 
ATOM   7254  C CD  A ARG C 1 31  ? -14.824 13.585  -93.296  0.50 58.91  ? 24   ARG C CD  1 
ATOM   7255  C CD  B ARG C 1 31  ? -14.473 13.687  -93.165  0.50 52.57  ? 24   ARG C CD  1 
ATOM   7256  N NE  A ARG C 1 31  ? -15.532 12.311  -93.280  0.50 58.84  ? 24   ARG C NE  1 
ATOM   7257  N NE  B ARG C 1 31  ? -13.013 13.746  -93.181  0.50 50.74  ? 24   ARG C NE  1 
ATOM   7258  C CZ  A ARG C 1 31  ? -16.335 11.889  -92.306  0.50 53.88  ? 24   ARG C CZ  1 
ATOM   7259  C CZ  B ARG C 1 31  ? -12.220 12.800  -93.681  0.50 48.90  ? 24   ARG C CZ  1 
ATOM   7260  N NH1 A ARG C 1 31  ? -16.553 12.641  -91.234  0.50 51.88  ? 24   ARG C NH1 1 
ATOM   7261  N NH1 B ARG C 1 31  ? -12.741 11.723  -94.245  0.50 49.86  ? 24   ARG C NH1 1 
ATOM   7262  N NH2 A ARG C 1 31  ? -16.919 10.709  -92.428  0.50 51.44  ? 24   ARG C NH2 1 
ATOM   7263  N NH2 B ARG C 1 31  ? -10.908 12.942  -93.625  0.50 46.28  ? 24   ARG C NH2 1 
ATOM   7264  N N   . THR C 1 32  ? -14.435 19.105  -93.546  1.00 49.46  ? 25   THR C N   1 
ATOM   7265  C CA  . THR C 1 32  ? -13.756 20.375  -93.877  1.00 50.06  ? 25   THR C CA  1 
ATOM   7266  C C   . THR C 1 32  ? -14.460 21.502  -93.131  1.00 47.27  ? 25   THR C C   1 
ATOM   7267  O O   . THR C 1 32  ? -15.634 21.347  -92.730  1.00 44.05  ? 25   THR C O   1 
ATOM   7268  C CB  . THR C 1 32  ? -13.792 20.662  -95.389  1.00 54.07  ? 25   THR C CB  1 
ATOM   7269  O OG1 . THR C 1 32  ? -15.136 20.617  -95.880  1.00 47.23  ? 25   THR C OG1 1 
ATOM   7270  C CG2 . THR C 1 32  ? -12.930 19.698  -96.175  1.00 54.09  ? 25   THR C CG2 1 
ATOM   7271  N N   . LEU C 1 33  ? -13.759 22.619  -92.976  1.00 48.33  ? 26   LEU C N   1 
ATOM   7272  C CA  . LEU C 1 33  ? -14.213 23.827  -92.256  1.00 51.45  ? 26   LEU C CA  1 
ATOM   7273  C C   . LEU C 1 33  ? -13.808 25.020  -93.115  1.00 54.71  ? 26   LEU C C   1 
ATOM   7274  O O   . LEU C 1 33  ? -12.608 25.098  -93.439  1.00 62.02  ? 26   LEU C O   1 
ATOM   7275  C CB  . LEU C 1 33  ? -13.491 23.860  -90.901  1.00 53.61  ? 26   LEU C CB  1 
ATOM   7276  C CG  . LEU C 1 33  ? -13.677 22.644  -89.982  1.00 49.10  ? 26   LEU C CG  1 
ATOM   7277  C CD1 . LEU C 1 33  ? -12.568 22.581  -88.934  1.00 48.33  ? 26   LEU C CD1 1 
ATOM   7278  C CD2 . LEU C 1 33  ? -15.040 22.700  -89.329  1.00 47.81  ? 26   LEU C CD2 1 
ATOM   7279  N N   . ASP C 1 34  ? -14.734 25.902  -93.490  1.00 55.03  ? 27   ASP C N   1 
ATOM   7280  C CA  . ASP C 1 34  ? -14.344 27.188  -94.127  1.00 62.84  ? 27   ASP C CA  1 
ATOM   7281  C C   . ASP C 1 34  ? -13.759 28.072  -93.019  1.00 61.80  ? 27   ASP C C   1 
ATOM   7282  O O   . ASP C 1 34  ? -13.848 27.665  -91.843  1.00 59.53  ? 27   ASP C O   1 
ATOM   7283  C CB  . ASP C 1 34  ? -15.490 27.831  -94.925  1.00 68.92  ? 27   ASP C CB  1 
ATOM   7284  C CG  . ASP C 1 34  ? -16.678 28.320  -94.107  1.00 73.38  ? 27   ASP C CG  1 
ATOM   7285  O OD1 . ASP C 1 34  ? -16.542 28.454  -92.888  1.00 79.88  ? 27   ASP C OD1 1 
ATOM   7286  O OD2 . ASP C 1 34  ? -17.728 28.570  -94.693  1.00 84.49  ? 27   ASP C OD2 1 
ATOM   7287  N N   . HIS C 1 35  ? -13.177 29.218  -93.378  1.00 61.33  ? 28   HIS C N   1 
ATOM   7288  C CA  . HIS C 1 35  ? -12.564 30.176  -92.425  1.00 65.18  ? 28   HIS C CA  1 
ATOM   7289  C C   . HIS C 1 35  ? -13.516 30.433  -91.246  1.00 66.36  ? 28   HIS C C   1 
ATOM   7290  O O   . HIS C 1 35  ? -13.032 30.462  -90.103  1.00 68.36  ? 28   HIS C O   1 
ATOM   7291  C CB  . HIS C 1 35  ? -12.162 31.469  -93.139  1.00 66.00  ? 28   HIS C CB  1 
ATOM   7292  C CG  . HIS C 1 35  ? -11.294 32.341  -92.300  1.00 71.53  ? 28   HIS C CG  1 
ATOM   7293  N ND1 . HIS C 1 35  ? -9.959  32.041  -92.057  1.00 78.36  ? 28   HIS C ND1 1 
ATOM   7294  C CD2 . HIS C 1 35  ? -11.558 33.482  -91.625  1.00 73.08  ? 28   HIS C CD2 1 
ATOM   7295  C CE1 . HIS C 1 35  ? -9.435  32.973  -91.283  1.00 77.60  ? 28   HIS C CE1 1 
ATOM   7296  N NE2 . HIS C 1 35  ? -10.399 33.869  -91.001  1.00 79.04  ? 28   HIS C NE2 1 
ATOM   7297  N N   . GLU C 1 36  ? -14.816 30.590  -91.507  1.00 67.35  ? 29   GLU C N   1 
ATOM   7298  C CA  . GLU C 1 36  ? -15.826 30.978  -90.482  1.00 71.36  ? 29   GLU C CA  1 
ATOM   7299  C C   . GLU C 1 36  ? -16.124 29.802  -89.545  1.00 66.92  ? 29   GLU C C   1 
ATOM   7300  O O   . GLU C 1 36  ? -16.239 30.042  -88.335  1.00 63.33  ? 29   GLU C O   1 
ATOM   7301  C CB  . GLU C 1 36  ? -17.103 31.524  -91.131  1.00 73.39  ? 29   GLU C CB  1 
ATOM   7302  C CG  . GLU C 1 36  ? -16.948 32.950  -91.637  1.00 78.53  ? 29   GLU C CG  1 
ATOM   7303  C CD  . GLU C 1 36  ? -16.134 33.860  -90.722  1.00 87.05  ? 29   GLU C CD  1 
ATOM   7304  O OE1 . GLU C 1 36  ? -16.555 34.064  -89.566  1.00 87.15  ? 29   GLU C OE1 1 
ATOM   7305  O OE2 . GLU C 1 36  ? -15.054 34.331  -91.148  1.00 89.53  ? 29   GLU C OE2 1 
ATOM   7306  N N   . GLU C 1 37  ? -16.254 28.587  -90.073  1.00 58.75  ? 30   GLU C N   1 
ATOM   7307  C CA  . GLU C 1 37  ? -16.548 27.385  -89.253  1.00 54.04  ? 30   GLU C CA  1 
ATOM   7308  C C   . GLU C 1 37  ? -15.342 27.100  -88.360  1.00 51.12  ? 30   GLU C C   1 
ATOM   7309  O O   . GLU C 1 37  ? -15.554 26.795  -87.184  1.00 48.17  ? 30   GLU C O   1 
ATOM   7310  C CB  . GLU C 1 37  ? -16.862 26.180  -90.132  1.00 52.13  ? 30   GLU C CB  1 
ATOM   7311  C CG  . GLU C 1 37  ? -18.185 26.312  -90.858  1.00 51.36  ? 30   GLU C CG  1 
ATOM   7312  C CD  . GLU C 1 37  ? -18.352 25.379  -92.044  1.00 51.86  ? 30   GLU C CD  1 
ATOM   7313  O OE1 . GLU C 1 37  ? -17.345 25.124  -92.756  1.00 51.77  ? 30   GLU C OE1 1 
ATOM   7314  O OE2 . GLU C 1 37  ? -19.480 24.886  -92.241  1.00 50.85  ? 30   GLU C OE2 1 
ATOM   7315  N N   . MET C 1 38  ? -14.136 27.209  -88.922  1.00 51.06  ? 31   MET C N   1 
ATOM   7316  C CA  . MET C 1 38  ? -12.836 27.039  -88.219  1.00 52.03  ? 31   MET C CA  1 
ATOM   7317  C C   . MET C 1 38  ? -12.750 28.056  -87.076  1.00 47.78  ? 31   MET C C   1 
ATOM   7318  O O   . MET C 1 38  ? -12.462 27.634  -85.947  1.00 47.85  ? 31   MET C O   1 
ATOM   7319  C CB  . MET C 1 38  ? -11.655 27.240  -89.181  1.00 53.99  ? 31   MET C CB  1 
ATOM   7320  C CG  . MET C 1 38  ? -10.279 27.177  -88.517  1.00 57.04  ? 31   MET C CG  1 
ATOM   7321  S SD  . MET C 1 38  ? -9.623  28.798  -87.990  1.00 63.93  ? 31   MET C SD  1 
ATOM   7322  C CE  . MET C 1 38  ? -9.335  29.566  -89.586  1.00 67.41  ? 31   MET C CE  1 
ATOM   7323  N N   . LYS C 1 39  ? -12.978 29.342  -87.365  1.00 46.39  ? 32   LYS C N   1 
ATOM   7324  C CA  . LYS C 1 39  ? -12.817 30.433  -86.368  1.00 49.11  ? 32   LYS C CA  1 
ATOM   7325  C C   . LYS C 1 39  ? -13.792 30.198  -85.218  1.00 44.94  ? 32   LYS C C   1 
ATOM   7326  O O   . LYS C 1 39  ? -13.395 30.405  -84.073  1.00 41.35  ? 32   LYS C O   1 
ATOM   7327  C CB  . LYS C 1 39  ? -13.024 31.822  -86.976  1.00 56.40  ? 32   LYS C CB  1 
ATOM   7328  C CG  . LYS C 1 39  ? -11.757 32.675  -87.046  1.00 64.60  ? 32   LYS C CG  1 
ATOM   7329  C CD  . LYS C 1 39  ? -11.849 33.855  -87.992  1.00 72.08  ? 32   LYS C CD  1 
ATOM   7330  C CE  . LYS C 1 39  ? -12.978 34.819  -87.672  1.00 80.18  ? 32   LYS C CE  1 
ATOM   7331  N NZ  . LYS C 1 39  ? -13.538 35.432  -88.904  1.00 87.89  ? 32   LYS C NZ  1 
ATOM   7332  N N   . ALA C 1 40  ? -15.009 29.760  -85.531  1.00 40.84  ? 33   ALA C N   1 
ATOM   7333  C CA  . ALA C 1 40  ? -16.085 29.502  -84.553  1.00 43.17  ? 33   ALA C CA  1 
ATOM   7334  C C   . ALA C 1 40  ? -15.731 28.291  -83.683  1.00 42.67  ? 33   ALA C C   1 
ATOM   7335  O O   . ALA C 1 40  ? -15.992 28.357  -82.463  1.00 42.85  ? 33   ALA C O   1 
ATOM   7336  C CB  . ALA C 1 40  ? -17.400 29.304  -85.267  1.00 45.34  ? 33   ALA C CB  1 
ATOM   7337  N N   . LEU C 1 41  ? -15.175 27.228  -84.277  1.00 40.21  ? 34   LEU C N   1 
ATOM   7338  C CA  . LEU C 1 41  ? -14.853 25.962  -83.555  1.00 38.26  ? 34   LEU C CA  1 
ATOM   7339  C C   . LEU C 1 41  ? -13.636 26.188  -82.663  1.00 39.96  ? 34   LEU C C   1 
ATOM   7340  O O   . LEU C 1 41  ? -13.667 25.755  -81.502  1.00 40.29  ? 34   LEU C O   1 
ATOM   7341  C CB  . LEU C 1 41  ? -14.587 24.830  -84.548  1.00 37.18  ? 34   LEU C CB  1 
ATOM   7342  C CG  . LEU C 1 41  ? -13.990 23.550  -83.961  1.00 35.07  ? 34   LEU C CG  1 
ATOM   7343  C CD1 . LEU C 1 41  ? -14.972 22.877  -83.035  1.00 36.47  ? 34   LEU C CD1 1 
ATOM   7344  C CD2 . LEU C 1 41  ? -13.602 22.589  -85.072  1.00 36.73  ? 34   LEU C CD2 1 
ATOM   7345  N N   . ASN C 1 42  ? -12.594 26.831  -83.186  1.00 43.55  ? 35   ASN C N   1 
ATOM   7346  C CA  . ASN C 1 42  ? -11.385 27.166  -82.398  1.00 43.05  ? 35   ASN C CA  1 
ATOM   7347  C C   . ASN C 1 42  ? -11.840 27.940  -81.151  1.00 43.35  ? 35   ASN C C   1 
ATOM   7348  O O   . ASN C 1 42  ? -11.451 27.546  -80.022  1.00 45.18  ? 35   ASN C O   1 
ATOM   7349  C CB  . ASN C 1 42  ? -10.345 27.894  -83.256  1.00 42.72  ? 35   ASN C CB  1 
ATOM   7350  C CG  . ASN C 1 42  ? -9.544  26.960  -84.147  1.00 46.05  ? 35   ASN C CG  1 
ATOM   7351  O OD1 . ASN C 1 42  ? -10.025 25.909  -84.574  1.00 41.12  ? 35   ASN C OD1 1 
ATOM   7352  N ND2 . ASN C 1 42  ? -8.289  27.309  -84.399  1.00 51.53  ? 35   ASN C ND2 1 
ATOM   7353  N N   . ARG C 1 43  ? -12.652 28.979  -81.348  1.00 44.09  ? 36   ARG C N   1 
ATOM   7354  C CA  . ARG C 1 43  ? -13.136 29.885  -80.278  1.00 51.26  ? 36   ARG C CA  1 
ATOM   7355  C C   . ARG C 1 43  ? -13.929 29.067  -79.240  1.00 48.35  ? 36   ARG C C   1 
ATOM   7356  O O   . ARG C 1 43  ? -13.748 29.307  -78.026  1.00 45.98  ? 36   ARG C O   1 
ATOM   7357  C CB  . ARG C 1 43  ? -13.929 31.027  -80.922  1.00 60.57  ? 36   ARG C CB  1 
ATOM   7358  C CG  . ARG C 1 43  ? -14.414 32.090  -79.946  1.00 73.34  ? 36   ARG C CG  1 
ATOM   7359  C CD  . ARG C 1 43  ? -14.875 33.378  -80.623  1.00 82.26  ? 36   ARG C CD  1 
ATOM   7360  N NE  . ARG C 1 43  ? -15.883 33.180  -81.678  1.00 87.09  ? 36   ARG C NE  1 
ATOM   7361  C CZ  . ARG C 1 43  ? -15.696 33.359  -82.994  1.00 87.43  ? 36   ARG C CZ  1 
ATOM   7362  N NH1 . ARG C 1 43  ? -14.525 33.755  -83.478  1.00 87.05  ? 36   ARG C NH1 1 
ATOM   7363  N NH2 . ARG C 1 43  ? -16.696 33.136  -83.830  1.00 81.25  ? 36   ARG C NH2 1 
ATOM   7364  N N   . GLU C 1 44  ? -14.747 28.110  -79.689  1.00 43.04  ? 37   GLU C N   1 
ATOM   7365  C CA  . GLU C 1 44  ? -15.547 27.219  -78.801  1.00 39.86  ? 37   GLU C CA  1 
ATOM   7366  C C   . GLU C 1 44  ? -14.607 26.324  -77.990  1.00 36.47  ? 37   GLU C C   1 
ATOM   7367  O O   . GLU C 1 44  ? -14.784 26.252  -76.769  1.00 33.98  ? 37   GLU C O   1 
ATOM   7368  C CB  . GLU C 1 44  ? -16.507 26.323  -79.587  1.00 40.05  ? 37   GLU C CB  1 
ATOM   7369  C CG  . GLU C 1 44  ? -17.959 26.736  -79.490  1.00 41.52  ? 37   GLU C CG  1 
ATOM   7370  C CD  . GLU C 1 44  ? -18.887 25.890  -80.354  1.00 45.99  ? 37   GLU C CD  1 
ATOM   7371  O OE1 . GLU C 1 44  ? -18.572 25.692  -81.550  1.00 48.66  ? 37   GLU C OE1 1 
ATOM   7372  O OE2 . GLU C 1 44  ? -19.913 25.408  -79.837  1.00 49.63  ? 37   GLU C OE2 1 
ATOM   7373  N N   . VAL C 1 45  ? -13.676 25.637  -78.653  1.00 34.43  ? 38   VAL C N   1 
ATOM   7374  C CA  . VAL C 1 45  ? -12.800 24.612  -78.009  1.00 34.36  ? 38   VAL C CA  1 
ATOM   7375  C C   . VAL C 1 45  ? -11.992 25.292  -76.892  1.00 36.65  ? 38   VAL C C   1 
ATOM   7376  O O   . VAL C 1 45  ? -11.860 24.697  -75.819  1.00 39.02  ? 38   VAL C O   1 
ATOM   7377  C CB  . VAL C 1 45  ? -11.914 23.880  -79.035  1.00 32.07  ? 38   VAL C CB  1 
ATOM   7378  C CG1 . VAL C 1 45  ? -10.825 23.054  -78.383  1.00 31.66  ? 38   VAL C CG1 1 
ATOM   7379  C CG2 . VAL C 1 45  ? -12.736 22.989  -79.939  1.00 31.92  ? 38   VAL C CG2 1 
ATOM   7380  N N   . ILE C 1 46  ? -11.515 26.516  -77.106  1.00 39.18  ? 39   ILE C N   1 
ATOM   7381  C CA  . ILE C 1 46  ? -10.704 27.257  -76.096  1.00 40.67  ? 39   ILE C CA  1 
ATOM   7382  C C   . ILE C 1 46  ? -11.603 27.638  -74.920  1.00 40.78  ? 39   ILE C C   1 
ATOM   7383  O O   . ILE C 1 46  ? -11.190 27.396  -73.785  1.00 39.04  ? 39   ILE C O   1 
ATOM   7384  C CB  . ILE C 1 46  ? -10.012 28.471  -76.736  1.00 45.90  ? 39   ILE C CB  1 
ATOM   7385  C CG1 . ILE C 1 46  ? -8.927  28.017  -77.718  1.00 49.65  ? 39   ILE C CG1 1 
ATOM   7386  C CG2 . ILE C 1 46  ? -9.461  29.416  -75.675  1.00 46.85  ? 39   ILE C CG2 1 
ATOM   7387  C CD1 . ILE C 1 46  ? -8.359  29.123  -78.564  1.00 51.95  ? 39   ILE C CD1 1 
ATOM   7388  N N   . GLU C 1 47  ? -12.782 28.198  -75.190  1.00 42.66  ? 40   GLU C N   1 
ATOM   7389  C CA  . GLU C 1 47  ? -13.788 28.534  -74.148  1.00 46.36  ? 40   GLU C CA  1 
ATOM   7390  C C   . GLU C 1 47  ? -14.111 27.269  -73.333  1.00 43.67  ? 40   GLU C C   1 
ATOM   7391  O O   . GLU C 1 47  ? -14.072 27.351  -72.091  1.00 42.49  ? 40   GLU C O   1 
ATOM   7392  C CB  . GLU C 1 47  ? -15.026 29.165  -74.797  1.00 53.57  ? 40   GLU C CB  1 
ATOM   7393  C CG  . GLU C 1 47  ? -16.224 29.365  -73.868  1.00 57.91  ? 40   GLU C CG  1 
ATOM   7394  C CD  . GLU C 1 47  ? -16.052 30.387  -72.751  1.00 66.78  ? 40   GLU C CD  1 
ATOM   7395  O OE1 . GLU C 1 47  ? -15.011 31.089  -72.725  1.00 73.25  ? 40   GLU C OE1 1 
ATOM   7396  O OE2 . GLU C 1 47  ? -16.964 30.486  -71.897  1.00 75.00  ? 40   GLU C OE2 1 
ATOM   7397  N N   . TYR C 1 48  ? -14.375 26.133  -73.991  1.00 39.46  ? 41   TYR C N   1 
ATOM   7398  C CA  . TYR C 1 48  ? -14.801 24.875  -73.317  1.00 36.66  ? 41   TYR C CA  1 
ATOM   7399  C C   . TYR C 1 48  ? -13.630 24.219  -72.569  1.00 34.58  ? 41   TYR C C   1 
ATOM   7400  O O   . TYR C 1 48  ? -13.895 23.613  -71.512  1.00 33.88  ? 41   TYR C O   1 
ATOM   7401  C CB  . TYR C 1 48  ? -15.454 23.892  -74.296  1.00 36.00  ? 41   TYR C CB  1 
ATOM   7402  C CG  . TYR C 1 48  ? -16.721 24.382  -74.943  1.00 37.67  ? 41   TYR C CG  1 
ATOM   7403  C CD1 . TYR C 1 48  ? -17.392 25.506  -74.479  1.00 39.08  ? 41   TYR C CD1 1 
ATOM   7404  C CD2 . TYR C 1 48  ? -17.271 23.702  -76.014  1.00 38.17  ? 41   TYR C CD2 1 
ATOM   7405  C CE1 . TYR C 1 48  ? -18.561 25.950  -75.076  1.00 40.34  ? 41   TYR C CE1 1 
ATOM   7406  C CE2 . TYR C 1 48  ? -18.442 24.131  -76.622  1.00 39.24  ? 41   TYR C CE2 1 
ATOM   7407  C CZ  . TYR C 1 48  ? -19.098 25.251  -76.143  1.00 40.50  ? 41   TYR C CZ  1 
ATOM   7408  O OH  . TYR C 1 48  ? -20.252 25.676  -76.741  1.00 45.16  ? 41   TYR C OH  1 
ATOM   7409  N N   . PHE C 1 49  ? -12.390 24.303  -73.062  1.00 33.56  ? 42   PHE C N   1 
ATOM   7410  C CA  . PHE C 1 49  ? -11.215 23.772  -72.318  1.00 35.82  ? 42   PHE C CA  1 
ATOM   7411  C C   . PHE C 1 49  ? -11.123 24.525  -70.987  1.00 38.18  ? 42   PHE C C   1 
ATOM   7412  O O   . PHE C 1 49  ? -10.973 23.891  -69.939  1.00 34.90  ? 42   PHE C O   1 
ATOM   7413  C CB  . PHE C 1 49  ? -9.917  23.861  -73.126  1.00 34.55  ? 42   PHE C CB  1 
ATOM   7414  C CG  . PHE C 1 49  ? -9.443  22.532  -73.654  1.00 34.51  ? 42   PHE C CG  1 
ATOM   7415  C CD1 . PHE C 1 49  ? -9.946  22.007  -74.837  1.00 35.47  ? 42   PHE C CD1 1 
ATOM   7416  C CD2 . PHE C 1 49  ? -8.513  21.787  -72.955  1.00 37.26  ? 42   PHE C CD2 1 
ATOM   7417  C CE1 . PHE C 1 49  ? -9.521  20.776  -75.315  1.00 35.18  ? 42   PHE C CE1 1 
ATOM   7418  C CE2 . PHE C 1 49  ? -8.076  20.560  -73.441  1.00 38.75  ? 42   PHE C CE2 1 
ATOM   7419  C CZ  . PHE C 1 49  ? -8.586  20.054  -74.617  1.00 37.24  ? 42   PHE C CZ  1 
ATOM   7420  N N   . LYS C 1 50  ? -11.277 25.844  -71.070  1.00 41.95  ? 43   LYS C N   1 
ATOM   7421  C CA  . LYS C 1 50  ? -11.215 26.815  -69.957  1.00 43.10  ? 43   LYS C CA  1 
ATOM   7422  C C   . LYS C 1 50  ? -12.341 26.545  -68.947  1.00 40.62  ? 43   LYS C C   1 
ATOM   7423  O O   . LYS C 1 50  ? -12.072 26.602  -67.723  1.00 37.33  ? 43   LYS C O   1 
ATOM   7424  C CB  . LYS C 1 50  ? -11.279 28.220  -70.556  1.00 49.28  ? 43   LYS C CB  1 
ATOM   7425  C CG  . LYS C 1 50  ? -11.271 29.350  -69.539  1.00 56.98  ? 43   LYS C CG  1 
ATOM   7426  C CD  . LYS C 1 50  ? -10.940 30.707  -70.138  1.00 65.38  ? 43   LYS C CD  1 
ATOM   7427  C CE  . LYS C 1 50  ? -11.652 31.853  -69.440  1.00 69.64  ? 43   LYS C CE  1 
ATOM   7428  N NZ  . LYS C 1 50  ? -13.112 31.858  -69.722  1.00 72.08  ? 43   LYS C NZ  1 
ATOM   7429  N N   . GLU C 1 51  ? -13.552 26.253  -69.419  1.00 39.72  ? 44   GLU C N   1 
ATOM   7430  C CA  . GLU C 1 51  ? -14.758 26.205  -68.549  1.00 37.91  ? 44   GLU C CA  1 
ATOM   7431  C C   . GLU C 1 51  ? -15.094 24.780  -68.093  1.00 36.31  ? 44   GLU C C   1 
ATOM   7432  O O   . GLU C 1 51  ? -15.886 24.675  -67.134  1.00 38.04  ? 44   GLU C O   1 
ATOM   7433  C CB  . GLU C 1 51  ? -15.967 26.817  -69.260  1.00 39.55  ? 44   GLU C CB  1 
ATOM   7434  C CG  . GLU C 1 51  ? -15.878 28.331  -69.414  1.00 40.78  ? 44   GLU C CG  1 
ATOM   7435  C CD  . GLU C 1 51  ? -15.702 29.086  -68.106  1.00 43.05  ? 44   GLU C CD  1 
ATOM   7436  O OE1 . GLU C 1 51  ? -16.452 28.784  -67.149  1.00 45.78  ? 44   GLU C OE1 1 
ATOM   7437  O OE2 . GLU C 1 51  ? -14.806 29.956  -68.044  1.00 45.20  ? 44   GLU C OE2 1 
ATOM   7438  N N   . HIS C 1 52  ? -14.559 23.726  -68.725  1.00 34.20  ? 45   HIS C N   1 
ATOM   7439  C CA  . HIS C 1 52  ? -15.069 22.341  -68.505  1.00 32.35  ? 45   HIS C CA  1 
ATOM   7440  C C   . HIS C 1 52  ? -14.006 21.237  -68.538  1.00 32.74  ? 45   HIS C C   1 
ATOM   7441  O O   . HIS C 1 52  ? -14.374 20.090  -68.201  1.00 31.74  ? 45   HIS C O   1 
ATOM   7442  C CB  . HIS C 1 52  ? -16.156 22.038  -69.530  1.00 31.90  ? 45   HIS C CB  1 
ATOM   7443  C CG  . HIS C 1 52  ? -17.306 22.975  -69.443  1.00 31.67  ? 45   HIS C CG  1 
ATOM   7444  N ND1 . HIS C 1 52  ? -18.070 23.079  -68.309  1.00 33.09  ? 45   HIS C ND1 1 
ATOM   7445  C CD2 . HIS C 1 52  ? -17.817 23.851  -70.330  1.00 32.74  ? 45   HIS C CD2 1 
ATOM   7446  C CE1 . HIS C 1 52  ? -19.022 23.970  -68.501  1.00 35.32  ? 45   HIS C CE1 1 
ATOM   7447  N NE2 . HIS C 1 52  ? -18.895 24.458  -69.740  1.00 35.11  ? 45   HIS C NE2 1 
ATOM   7448  N N   . VAL C 1 53  ? -12.762 21.527  -68.934  1.00 32.56  ? 46   VAL C N   1 
ATOM   7449  C CA  . VAL C 1 53  ? -11.689 20.494  -69.057  1.00 33.57  ? 46   VAL C CA  1 
ATOM   7450  C C   . VAL C 1 53  ? -10.544 20.850  -68.109  1.00 32.14  ? 46   VAL C C   1 
ATOM   7451  O O   . VAL C 1 53  ? -10.337 20.098  -67.148  1.00 30.73  ? 46   VAL C O   1 
ATOM   7452  C CB  . VAL C 1 53  ? -11.176 20.349  -70.502  1.00 36.29  ? 46   VAL C CB  1 
ATOM   7453  C CG1 . VAL C 1 53  ? -10.213 19.176  -70.631  1.00 35.76  ? 46   VAL C CG1 1 
ATOM   7454  C CG2 . VAL C 1 53  ? -12.325 20.225  -71.495  1.00 37.46  ? 46   VAL C CG2 1 
ATOM   7455  N N   . ASN C 1 54  ? -9.839  21.949  -68.378  1.00 31.65  ? 47   ASN C N   1 
ATOM   7456  C CA  . ASN C 1 54  ? -8.691  22.402  -67.559  1.00 34.27  ? 47   ASN C CA  1 
ATOM   7457  C C   . ASN C 1 54  ? -8.098  23.680  -68.142  1.00 34.01  ? 47   ASN C C   1 
ATOM   7458  O O   . ASN C 1 54  ? -7.382  23.617  -69.129  1.00 34.07  ? 47   ASN C O   1 
ATOM   7459  C CB  . ASN C 1 54  ? -7.609  21.323  -67.488  1.00 35.37  ? 47   ASN C CB  1 
ATOM   7460  C CG  . ASN C 1 54  ? -6.708  21.497  -66.289  1.00 35.32  ? 47   ASN C CG  1 
ATOM   7461  O OD1 . ASN C 1 54  ? -6.295  22.610  -65.998  1.00 38.13  ? 47   ASN C OD1 1 
ATOM   7462  N ND2 . ASN C 1 54  ? -6.432  20.418  -65.575  1.00 36.17  ? 47   ASN C ND2 1 
ATOM   7463  N N   . PRO C 1 55  ? -8.303  24.871  -67.536  1.00 35.25  ? 48   PRO C N   1 
ATOM   7464  C CA  . PRO C 1 55  ? -7.665  26.091  -68.035  1.00 36.02  ? 48   PRO C CA  1 
ATOM   7465  C C   . PRO C 1 55  ? -6.130  26.030  -67.935  1.00 36.81  ? 48   PRO C C   1 
ATOM   7466  O O   . PRO C 1 55  ? -5.460  26.822  -68.595  1.00 33.94  ? 48   PRO C O   1 
ATOM   7467  C CB  . PRO C 1 55  ? -8.221  27.173  -67.104  1.00 36.77  ? 48   PRO C CB  1 
ATOM   7468  C CG  . PRO C 1 55  ? -8.516  26.414  -65.822  1.00 37.08  ? 48   PRO C CG  1 
ATOM   7469  C CD  . PRO C 1 55  ? -9.093  25.105  -66.318  1.00 36.90  ? 48   PRO C CD  1 
ATOM   7470  N N   . GLY C 1 56  ? -5.623  25.106  -67.112  1.00 35.03  ? 49   GLY C N   1 
ATOM   7471  C CA  . GLY C 1 56  ? -4.189  24.805  -66.961  1.00 40.35  ? 49   GLY C CA  1 
ATOM   7472  C C   . GLY C 1 56  ? -3.557  24.304  -68.247  1.00 40.70  ? 49   GLY C C   1 
ATOM   7473  O O   . GLY C 1 56  ? -2.408  24.694  -68.516  1.00 44.67  ? 49   GLY C O   1 
ATOM   7474  N N   . PHE C 1 57  ? -4.255  23.453  -69.008  1.00 44.35  ? 50   PHE C N   1 
ATOM   7475  C CA  . PHE C 1 57  ? -3.747  22.895  -70.284  1.00 45.54  ? 50   PHE C CA  1 
ATOM   7476  C C   . PHE C 1 57  ? -3.496  24.067  -71.253  1.00 46.84  ? 50   PHE C C   1 
ATOM   7477  O O   . PHE C 1 57  ? -2.491  24.009  -71.974  1.00 54.73  ? 50   PHE C O   1 
ATOM   7478  C CB  . PHE C 1 57  ? -4.651  21.775  -70.810  1.00 49.41  ? 50   PHE C CB  1 
ATOM   7479  C CG  . PHE C 1 57  ? -3.913  20.809  -71.703  1.00 58.81  ? 50   PHE C CG  1 
ATOM   7480  C CD1 . PHE C 1 57  ? -3.039  19.881  -71.159  1.00 60.82  ? 50   PHE C CD1 1 
ATOM   7481  C CD2 . PHE C 1 57  ? -4.036  20.856  -73.092  1.00 65.26  ? 50   PHE C CD2 1 
ATOM   7482  C CE1 . PHE C 1 57  ? -2.325  19.012  -71.979  1.00 65.55  ? 50   PHE C CE1 1 
ATOM   7483  C CE2 . PHE C 1 57  ? -3.320  19.987  -73.909  1.00 62.53  ? 50   PHE C CE2 1 
ATOM   7484  C CZ  . PHE C 1 57  ? -2.468  19.062  -73.353  1.00 61.85  ? 50   PHE C CZ  1 
ATOM   7485  N N   . LEU C 1 58  ? -4.310  25.128  -71.225  1.00 43.41  ? 51   LEU C N   1 
ATOM   7486  C CA  . LEU C 1 58  ? -4.139  26.310  -72.113  1.00 43.55  ? 51   LEU C CA  1 
ATOM   7487  C C   . LEU C 1 58  ? -2.899  27.121  -71.697  1.00 46.78  ? 51   LEU C C   1 
ATOM   7488  O O   . LEU C 1 58  ? -2.242  27.716  -72.591  1.00 44.64  ? 51   LEU C O   1 
ATOM   7489  C CB  . LEU C 1 58  ? -5.397  27.178  -72.070  1.00 41.48  ? 51   LEU C CB  1 
ATOM   7490  C CG  . LEU C 1 58  ? -6.669  26.514  -72.597  1.00 41.77  ? 51   LEU C CG  1 
ATOM   7491  C CD1 . LEU C 1 58  ? -7.889  27.372  -72.306  1.00 45.49  ? 51   LEU C CD1 1 
ATOM   7492  C CD2 . LEU C 1 58  ? -6.586  26.229  -74.085  1.00 42.01  ? 51   LEU C CD2 1 
ATOM   7493  N N   . GLU C 1 59  ? -2.587  27.174  -70.402  1.00 47.74  ? 52   GLU C N   1 
ATOM   7494  C CA  . GLU C 1 59  ? -1.390  27.894  -69.890  1.00 54.00  ? 52   GLU C CA  1 
ATOM   7495  C C   . GLU C 1 59  ? -0.124  27.143  -70.303  1.00 50.99  ? 52   GLU C C   1 
ATOM   7496  O O   . GLU C 1 59  ? 0.831   27.827  -70.691  1.00 50.35  ? 52   GLU C O   1 
ATOM   7497  C CB  . GLU C 1 59  ? -1.442  28.078  -68.369  1.00 64.03  ? 52   GLU C CB  1 
ATOM   7498  C CG  . GLU C 1 59  ? -2.491  29.089  -67.920  1.00 69.55  ? 52   GLU C CG  1 
ATOM   7499  C CD  . GLU C 1 59  ? -2.314  30.469  -68.540  1.00 76.45  ? 52   GLU C CD  1 
ATOM   7500  O OE1 . GLU C 1 59  ? -1.272  31.110  -68.257  1.00 78.81  ? 52   GLU C OE1 1 
ATOM   7501  O OE2 . GLU C 1 59  ? -3.196  30.886  -69.331  1.00 70.85  ? 52   GLU C OE2 1 
ATOM   7502  N N   . TYR C 1 60  ? -0.114  25.806  -70.194  1.00 51.21  ? 53   TYR C N   1 
ATOM   7503  C CA  . TYR C 1 60  ? 1.048   24.938  -70.532  1.00 53.21  ? 53   TYR C CA  1 
ATOM   7504  C C   . TYR C 1 60  ? 1.399   25.085  -72.017  1.00 52.97  ? 53   TYR C C   1 
ATOM   7505  O O   . TYR C 1 60  ? 2.574   25.328  -72.340  1.00 49.93  ? 53   TYR C O   1 
ATOM   7506  C CB  . TYR C 1 60  ? 0.791   23.451  -70.269  1.00 55.33  ? 53   TYR C CB  1 
ATOM   7507  C CG  . TYR C 1 60  ? 1.621   22.522  -71.135  1.00 63.71  ? 53   TYR C CG  1 
ATOM   7508  C CD1 . TYR C 1 60  ? 2.982   22.316  -70.891  1.00 62.92  ? 53   TYR C CD1 1 
ATOM   7509  C CD2 . TYR C 1 60  ? 1.055   21.850  -72.215  1.00 61.82  ? 53   TYR C CD2 1 
ATOM   7510  C CE1 . TYR C 1 60  ? 3.743   21.448  -71.662  1.00 60.55  ? 53   TYR C CE1 1 
ATOM   7511  C CE2 . TYR C 1 60  ? 1.809   20.993  -73.008  1.00 62.73  ? 53   TYR C CE2 1 
ATOM   7512  C CZ  . TYR C 1 60  ? 3.157   20.788  -72.733  1.00 64.07  ? 53   TYR C CZ  1 
ATOM   7513  O OH  . TYR C 1 60  ? 3.894   19.936  -73.515  1.00 58.06  ? 53   TYR C OH  1 
ATOM   7514  N N   . ARG C 1 61  ? 0.403   24.900  -72.882  1.00 52.19  ? 54   ARG C N   1 
ATOM   7515  C CA  . ARG C 1 61  ? 0.541   24.941  -74.360  1.00 54.15  ? 54   ARG C CA  1 
ATOM   7516  C C   . ARG C 1 61  ? 1.083   26.309  -74.815  1.00 54.37  ? 54   ARG C C   1 
ATOM   7517  O O   . ARG C 1 61  ? 1.794   26.328  -75.833  1.00 50.72  ? 54   ARG C O   1 
ATOM   7518  C CB  . ARG C 1 61  ? -0.805  24.560  -74.977  1.00 55.99  ? 54   ARG C CB  1 
ATOM   7519  C CG  . ARG C 1 61  ? -1.036  23.053  -75.010  1.00 58.60  ? 54   ARG C CG  1 
ATOM   7520  C CD  . ARG C 1 61  ? -0.230  22.437  -76.147  1.00 63.08  ? 54   ARG C CD  1 
ATOM   7521  N NE  . ARG C 1 61  ? -0.664  23.072  -77.391  1.00 67.46  ? 54   ARG C NE  1 
ATOM   7522  C CZ  . ARG C 1 61  ? 0.113   23.573  -78.352  1.00 67.47  ? 54   ARG C CZ  1 
ATOM   7523  N NH1 . ARG C 1 61  ? -0.473  24.164  -79.386  1.00 76.67  ? 54   ARG C NH1 1 
ATOM   7524  N NH2 . ARG C 1 61  ? 1.430   23.450  -78.296  1.00 61.99  ? 54   ARG C NH2 1 
ATOM   7525  N N   . LYS C 1 62  ? 0.820   27.385  -74.055  1.00 56.85  ? 55   LYS C N   1 
ATOM   7526  C CA  . LYS C 1 62  ? 1.349   28.766  -74.296  1.00 57.14  ? 55   LYS C CA  1 
ATOM   7527  C C   . LYS C 1 62  ? 2.865   28.825  -74.046  1.00 52.57  ? 55   LYS C C   1 
ATOM   7528  O O   . LYS C 1 62  ? 3.567   29.446  -74.875  1.00 45.13  ? 55   LYS C O   1 
ATOM   7529  C CB  . LYS C 1 62  ? 0.645   29.811  -73.419  1.00 58.42  ? 55   LYS C CB  1 
ATOM   7530  C CG  . LYS C 1 62  ? -0.614  30.421  -74.028  1.00 64.36  ? 55   LYS C CG  1 
ATOM   7531  C CD  . LYS C 1 62  ? -1.290  31.445  -73.134  1.00 64.90  ? 55   LYS C CD  1 
ATOM   7532  C CE  . LYS C 1 62  ? -2.780  31.584  -73.377  1.00 66.08  ? 55   LYS C CE  1 
ATOM   7533  N NZ  . LYS C 1 62  ? -3.564  30.887  -72.329  1.00 69.51  ? 55   LYS C NZ  1 
ATOM   7534  N N   . SER C 1 63  ? 3.330   28.218  -72.942  1.00 53.95  ? 56   SER C N   1 
ATOM   7535  C CA  . SER C 1 63  ? 4.753   28.132  -72.496  1.00 55.82  ? 56   SER C CA  1 
ATOM   7536  C C   . SER C 1 63  ? 5.588   27.398  -73.557  1.00 51.09  ? 56   SER C C   1 
ATOM   7537  O O   . SER C 1 63  ? 6.814   27.632  -73.641  1.00 43.42  ? 56   SER C O   1 
ATOM   7538  C CB  . SER C 1 63  ? 4.882   27.495  -71.088  1.00 57.69  ? 56   SER C CB  1 
ATOM   7539  O OG  . SER C 1 63  ? 4.822   26.065  -71.098  1.00 55.93  ? 56   SER C OG  1 
ATOM   7540  N N   . VAL C 1 64  ? 4.939   26.543  -74.343  1.00 49.39  ? 57   VAL C N   1 
ATOM   7541  C CA  . VAL C 1 64  ? 5.596   25.710  -75.390  1.00 56.72  ? 57   VAL C CA  1 
ATOM   7542  C C   . VAL C 1 64  ? 5.137   26.176  -76.794  1.00 63.06  ? 57   VAL C C   1 
ATOM   7543  O O   . VAL C 1 64  ? 5.127   25.334  -77.727  1.00 67.91  ? 57   VAL C O   1 
ATOM   7544  C CB  . VAL C 1 64  ? 5.349   24.208  -75.130  1.00 54.33  ? 57   VAL C CB  1 
ATOM   7545  C CG1 . VAL C 1 64  ? 6.149   23.694  -73.936  1.00 55.02  ? 57   VAL C CG1 1 
ATOM   7546  C CG2 . VAL C 1 64  ? 3.872   23.862  -74.993  1.00 55.96  ? 57   VAL C CG2 1 
ATOM   7547  N N   . THR C 1 65  ? 4.825   27.473  -76.972  1.00 66.41  ? 58   THR C N   1 
ATOM   7548  C CA  . THR C 1 65  ? 4.438   28.089  -78.276  1.00 69.71  ? 58   THR C CA  1 
ATOM   7549  C C   . THR C 1 65  ? 4.651   29.614  -78.262  1.00 75.64  ? 58   THR C C   1 
ATOM   7550  O O   . THR C 1 65  ? 4.765   30.208  -77.155  1.00 72.78  ? 58   THR C O   1 
ATOM   7551  C CB  . THR C 1 65  ? 2.969   27.812  -78.639  1.00 66.47  ? 58   THR C CB  1 
ATOM   7552  O OG1 . THR C 1 65  ? 2.127   28.296  -77.589  1.00 66.99  ? 58   THR C OG1 1 
ATOM   7553  C CG2 . THR C 1 65  ? 2.655   26.352  -78.895  1.00 61.58  ? 58   THR C CG2 1 
ATOM   7554  N N   . ALA C 1 66  ? 4.696   30.215  -79.460  1.00 80.50  ? 59   ALA C N   1 
ATOM   7555  C CA  . ALA C 1 66  ? 4.561   31.671  -79.691  1.00 78.20  ? 59   ALA C CA  1 
ATOM   7556  C C   . ALA C 1 66  ? 3.065   31.972  -79.857  1.00 80.59  ? 59   ALA C C   1 
ATOM   7557  O O   . ALA C 1 66  ? 2.504   31.582  -80.899  1.00 71.92  ? 59   ALA C O   1 
ATOM   7558  C CB  . ALA C 1 66  ? 5.378   32.098  -80.889  1.00 74.04  ? 59   ALA C CB  1 
ATOM   7559  N N   . GLY C 1 67  ? 2.453   32.578  -78.827  1.00 88.12  ? 60   GLY C N   1 
ATOM   7560  C CA  . GLY C 1 67  ? 1.008   32.883  -78.702  1.00 87.30  ? 60   GLY C CA  1 
ATOM   7561  C C   . GLY C 1 67  ? 0.270   32.872  -80.029  1.00 88.77  ? 60   GLY C C   1 
ATOM   7562  O O   . GLY C 1 67  ? 0.863   33.287  -81.042  1.00 94.10  ? 60   GLY C O   1 
ATOM   7563  N N   . GLY C 1 68  ? -0.997  32.450  -80.021  1.00 89.54  ? 61   GLY C N   1 
ATOM   7564  C CA  . GLY C 1 68  ? -1.789  32.198  -81.242  1.00 78.29  ? 61   GLY C CA  1 
ATOM   7565  C C   . GLY C 1 68  ? -1.590  30.778  -81.730  1.00 68.66  ? 61   GLY C C   1 
ATOM   7566  O O   . GLY C 1 68  ? -2.577  30.184  -82.203  1.00 63.22  ? 61   GLY C O   1 
ATOM   7567  N N   . ASP C 1 69  ? -0.364  30.256  -81.584  1.00 63.81  ? 62   ASP C N   1 
ATOM   7568  C CA  . ASP C 1 69  ? 0.009   28.855  -81.911  1.00 70.17  ? 62   ASP C CA  1 
ATOM   7569  C C   . ASP C 1 69  ? -0.500  27.884  -80.833  1.00 73.10  ? 62   ASP C C   1 
ATOM   7570  O O   . ASP C 1 69  ? -0.764  26.723  -81.184  1.00 88.88  ? 62   ASP C O   1 
ATOM   7571  C CB  . ASP C 1 69  ? 1.521   28.687  -82.133  1.00 76.18  ? 62   ASP C CB  1 
ATOM   7572  C CG  . ASP C 1 69  ? 1.915   28.753  -83.608  1.00 80.92  ? 62   ASP C CG  1 
ATOM   7573  O OD1 . ASP C 1 69  ? 1.422   29.698  -84.247  1.00 83.04  ? 62   ASP C OD1 1 
ATOM   7574  O OD2 . ASP C 1 69  ? 2.732   27.928  -84.112  1.00 78.24  ? 62   ASP C OD2 1 
ATOM   7575  N N   . TYR C 1 70  ? -0.620  28.309  -79.570  1.00 69.95  ? 63   TYR C N   1 
ATOM   7576  C CA  . TYR C 1 70  ? -1.109  27.455  -78.454  1.00 66.71  ? 63   TYR C CA  1 
ATOM   7577  C C   . TYR C 1 70  ? -2.523  26.956  -78.766  1.00 65.75  ? 63   TYR C C   1 
ATOM   7578  O O   . TYR C 1 70  ? -2.849  25.814  -78.372  1.00 53.91  ? 63   TYR C O   1 
ATOM   7579  C CB  . TYR C 1 70  ? -1.107  28.224  -77.134  1.00 68.72  ? 63   TYR C CB  1 
ATOM   7580  C CG  . TYR C 1 70  ? -2.325  29.086  -76.927  1.00 69.65  ? 63   TYR C CG  1 
ATOM   7581  C CD1 . TYR C 1 70  ? -2.388  30.362  -77.462  1.00 70.11  ? 63   TYR C CD1 1 
ATOM   7582  C CD2 . TYR C 1 70  ? -3.418  28.630  -76.205  1.00 69.82  ? 63   TYR C CD2 1 
ATOM   7583  C CE1 . TYR C 1 70  ? -3.506  31.167  -77.295  1.00 72.77  ? 63   TYR C CE1 1 
ATOM   7584  C CE2 . TYR C 1 70  ? -4.544  29.423  -76.026  1.00 73.12  ? 63   TYR C CE2 1 
ATOM   7585  C CZ  . TYR C 1 70  ? -4.590  30.698  -76.569  1.00 75.71  ? 63   TYR C CZ  1 
ATOM   7586  O OH  . TYR C 1 70  ? -5.699  31.479  -76.386  1.00 73.12  ? 63   TYR C OH  1 
ATOM   7587  N N   . GLY C 1 71  ? -3.305  27.800  -79.465  1.00 68.92  ? 64   GLY C N   1 
ATOM   7588  C CA  . GLY C 1 71  ? -4.714  27.587  -79.864  1.00 64.03  ? 64   GLY C CA  1 
ATOM   7589  C C   . GLY C 1 71  ? -4.840  26.869  -81.199  1.00 62.32  ? 64   GLY C C   1 
ATOM   7590  O O   . GLY C 1 71  ? -5.742  27.231  -82.006  1.00 66.27  ? 64   GLY C O   1 
ATOM   7591  N N   . ALA C 1 72  ? -3.956  25.888  -81.419  1.00 54.30  ? 65   ALA C N   1 
ATOM   7592  C CA  . ALA C 1 72  ? -4.037  24.866  -82.480  1.00 45.71  ? 65   ALA C CA  1 
ATOM   7593  C C   . ALA C 1 72  ? -4.971  23.746  -82.006  1.00 40.35  ? 65   ALA C C   1 
ATOM   7594  O O   . ALA C 1 72  ? -4.769  23.231  -80.891  1.00 34.86  ? 65   ALA C O   1 
ATOM   7595  C CB  . ALA C 1 72  ? -2.657  24.349  -82.795  1.00 43.69  ? 65   ALA C CB  1 
ATOM   7596  N N   . VAL C 1 73  ? -5.952  23.407  -82.842  1.00 34.68  ? 66   VAL C N   1 
ATOM   7597  C CA  . VAL C 1 73  ? -6.977  22.364  -82.583  1.00 34.06  ? 66   VAL C CA  1 
ATOM   7598  C C   . VAL C 1 73  ? -6.775  21.230  -83.588  1.00 35.53  ? 66   VAL C C   1 
ATOM   7599  O O   . VAL C 1 73  ? -6.855  21.499  -84.787  1.00 40.55  ? 66   VAL C O   1 
ATOM   7600  C CB  . VAL C 1 73  ? -8.391  22.965  -82.676  1.00 33.09  ? 66   VAL C CB  1 
ATOM   7601  C CG1 . VAL C 1 73  ? -9.452  21.964  -82.240  1.00 30.90  ? 66   VAL C CG1 1 
ATOM   7602  C CG2 . VAL C 1 73  ? -8.486  24.269  -81.887  1.00 33.27  ? 66   VAL C CG2 1 
ATOM   7603  N N   . GLU C 1 74  ? -6.512  20.017  -83.106  1.00 37.15  ? 67   GLU C N   1 
ATOM   7604  C CA  . GLU C 1 74  ? -6.407  18.781  -83.928  1.00 38.79  ? 67   GLU C CA  1 
ATOM   7605  C C   . GLU C 1 74  ? -7.672  18.623  -84.753  1.00 37.78  ? 67   GLU C C   1 
ATOM   7606  O O   . GLU C 1 74  ? -8.741  18.933  -84.211  1.00 37.18  ? 67   GLU C O   1 
ATOM   7607  C CB  . GLU C 1 74  ? -6.333  17.534  -83.054  1.00 43.16  ? 67   GLU C CB  1 
ATOM   7608  C CG  . GLU C 1 74  ? -4.971  16.879  -83.053  1.00 46.49  ? 67   GLU C CG  1 
ATOM   7609  C CD  . GLU C 1 74  ? -4.731  16.058  -81.796  1.00 49.44  ? 67   GLU C CD  1 
ATOM   7610  O OE1 . GLU C 1 74  ? -5.729  15.569  -81.237  1.00 66.31  ? 67   GLU C OE1 1 
ATOM   7611  O OE2 . GLU C 1 74  ? -3.579  15.926  -81.358  1.00 44.01  ? 67   GLU C OE2 1 
ATOM   7612  N N   . TRP C 1 75  ? -7.554  18.128  -85.985  1.00 38.76  ? 68   TRP C N   1 
ATOM   7613  C CA  . TRP C 1 75  ? -8.715  17.913  -86.889  1.00 39.22  ? 68   TRP C CA  1 
ATOM   7614  C C   . TRP C 1 75  ? -8.679  16.501  -87.503  1.00 38.61  ? 68   TRP C C   1 
ATOM   7615  O O   . TRP C 1 75  ? -9.669  15.748  -87.369  1.00 34.27  ? 68   TRP C O   1 
ATOM   7616  C CB  . TRP C 1 75  ? -8.781  19.021  -87.947  1.00 41.68  ? 68   TRP C CB  1 
ATOM   7617  C CG  . TRP C 1 75  ? -10.024 18.943  -88.787  1.00 44.34  ? 68   TRP C CG  1 
ATOM   7618  C CD1 . TRP C 1 75  ? -10.072 18.817  -90.145  1.00 46.01  ? 68   TRP C CD1 1 
ATOM   7619  C CD2 . TRP C 1 75  ? -11.400 18.953  -88.343  1.00 40.46  ? 68   TRP C CD2 1 
ATOM   7620  N NE1 . TRP C 1 75  ? -11.372 18.760  -90.576  1.00 47.59  ? 68   TRP C NE1 1 
ATOM   7621  C CE2 . TRP C 1 75  ? -12.208 18.846  -89.494  1.00 42.70  ? 68   TRP C CE2 1 
ATOM   7622  C CE3 . TRP C 1 75  ? -12.029 19.054  -87.102  1.00 41.59  ? 68   TRP C CE3 1 
ATOM   7623  C CZ2 . TRP C 1 75  ? -13.600 18.846  -89.448  1.00 39.75  ? 68   TRP C CZ2 1 
ATOM   7624  C CZ3 . TRP C 1 75  ? -13.408 19.060  -87.048  1.00 38.33  ? 68   TRP C CZ3 1 
ATOM   7625  C CH2 . TRP C 1 75  ? -14.177 18.952  -88.207  1.00 39.98  ? 68   TRP C CH2 1 
ATOM   7626  N N   . GLN C 1 76  ? -7.587  16.123  -88.162  1.00 42.89  ? 69   GLN C N   1 
ATOM   7627  C CA  . GLN C 1 76  ? -7.494  14.785  -88.800  1.00 40.42  ? 69   GLN C CA  1 
ATOM   7628  C C   . GLN C 1 76  ? -6.028  14.417  -89.027  1.00 38.31  ? 69   GLN C C   1 
ATOM   7629  O O   . GLN C 1 76  ? -5.150  15.328  -88.993  1.00 39.74  ? 69   GLN C O   1 
ATOM   7630  C CB  . GLN C 1 76  ? -8.293  14.785  -90.103  1.00 42.49  ? 69   GLN C CB  1 
ATOM   7631  C CG  . GLN C 1 76  ? -7.705  15.701  -91.175  1.00 45.14  ? 69   GLN C CG  1 
ATOM   7632  C CD  . GLN C 1 76  ? -8.545  15.818  -92.420  1.00 49.49  ? 69   GLN C CD  1 
ATOM   7633  O OE1 . GLN C 1 76  ? -9.305  14.917  -92.773  1.00 54.27  ? 69   GLN C OE1 1 
ATOM   7634  N NE2 . GLN C 1 76  ? -8.401  16.949  -93.093  1.00 50.44  ? 69   GLN C NE2 1 
ATOM   7635  N N   . ALA C 1 77  ? -5.795  13.122  -89.250  1.00 35.72  ? 70   ALA C N   1 
ATOM   7636  C CA  . ALA C 1 77  ? -4.532  12.565  -89.790  1.00 34.52  ? 70   ALA C CA  1 
ATOM   7637  C C   . ALA C 1 77  ? -4.334  13.092  -91.217  1.00 34.80  ? 70   ALA C C   1 
ATOM   7638  O O   . ALA C 1 77  ? -5.327  13.099  -91.969  1.00 33.33  ? 70   ALA C O   1 
ATOM   7639  C CB  . ALA C 1 77  ? -4.602  11.064  -89.780  1.00 33.48  ? 70   ALA C CB  1 
ATOM   7640  N N   . GLY C 1 78  ? -3.115  13.518  -91.566  1.00 32.42  ? 71   GLY C N   1 
ATOM   7641  C CA  . GLY C 1 78  ? -2.742  13.918  -92.936  1.00 32.67  ? 71   GLY C CA  1 
ATOM   7642  C C   . GLY C 1 78  ? -2.320  12.718  -93.762  1.00 31.69  ? 71   GLY C C   1 
ATOM   7643  O O   . GLY C 1 78  ? -3.109  12.238  -94.552  1.00 38.95  ? 71   GLY C O   1 
ATOM   7644  N N   . SER C 1 79  ? -1.093  12.261  -93.574  1.00 30.53  ? 72   SER C N   1 
ATOM   7645  C CA  . SER C 1 79  ? -0.555  10.987  -94.101  1.00 29.93  ? 72   SER C CA  1 
ATOM   7646  C C   . SER C 1 79  ? -0.245  10.101  -92.896  1.00 26.93  ? 72   SER C C   1 
ATOM   7647  O O   . SER C 1 79  ? -0.624  10.492  -91.790  1.00 25.93  ? 72   SER C O   1 
ATOM   7648  C CB  . SER C 1 79  ? 0.667   11.273  -94.943  1.00 32.01  ? 72   SER C CB  1 
ATOM   7649  O OG  . SER C 1 79  ? 1.521   12.185  -94.266  1.00 34.39  ? 72   SER C OG  1 
ATOM   7650  N N   . LEU C 1 80  ? 0.446   8.977   -93.084  1.00 25.55  ? 73   LEU C N   1 
ATOM   7651  C CA  . LEU C 1 80  ? 0.861   8.082   -91.973  1.00 24.50  ? 73   LEU C CA  1 
ATOM   7652  C C   . LEU C 1 80  ? 1.531   8.885   -90.864  1.00 24.69  ? 73   LEU C C   1 
ATOM   7653  O O   . LEU C 1 80  ? 1.331   8.515   -89.704  1.00 26.88  ? 73   LEU C O   1 
ATOM   7654  C CB  . LEU C 1 80  ? 1.831   7.012   -92.468  1.00 24.75  ? 73   LEU C CB  1 
ATOM   7655  C CG  . LEU C 1 80  ? 1.199   5.703   -92.919  1.00 25.65  ? 73   LEU C CG  1 
ATOM   7656  C CD1 . LEU C 1 80  ? 2.238   4.811   -93.576  1.00 27.62  ? 73   LEU C CD1 1 
ATOM   7657  C CD2 . LEU C 1 80  ? 0.563   4.981   -91.754  1.00 26.09  ? 73   LEU C CD2 1 
ATOM   7658  N N   . ASN C 1 81  ? 2.316   9.912   -91.193  1.00 23.54  ? 74   ASN C N   1 
ATOM   7659  C CA  . ASN C 1 81  ? 3.275   10.515  -90.227  1.00 23.41  ? 74   ASN C CA  1 
ATOM   7660  C C   . ASN C 1 81  ? 2.959   11.991  -89.997  1.00 22.13  ? 74   ASN C C   1 
ATOM   7661  O O   . ASN C 1 81  ? 3.808   12.663  -89.399  1.00 21.61  ? 74   ASN C O   1 
ATOM   7662  C CB  . ASN C 1 81  ? 4.716   10.328  -90.717  1.00 23.59  ? 74   ASN C CB  1 
ATOM   7663  C CG  . ASN C 1 81  ? 5.006   8.892   -91.095  1.00 23.09  ? 74   ASN C CG  1 
ATOM   7664  O OD1 . ASN C 1 81  ? 4.683   7.980   -90.331  1.00 22.71  ? 74   ASN C OD1 1 
ATOM   7665  N ND2 . ASN C 1 81  ? 5.605   8.691   -92.259  1.00 22.48  ? 74   ASN C ND2 1 
ATOM   7666  N N   . THR C 1 82  ? 1.805   12.481  -90.424  1.00 22.57  ? 75   THR C N   1 
ATOM   7667  C CA  . THR C 1 82  ? 1.446   13.908  -90.247  1.00 25.34  ? 75   THR C CA  1 
ATOM   7668  C C   . THR C 1 82  ? 0.055   14.076  -89.616  1.00 28.04  ? 75   THR C C   1 
ATOM   7669  O O   . THR C 1 82  ? -0.812  13.176  -89.736  1.00 26.44  ? 75   THR C O   1 
ATOM   7670  C CB  . THR C 1 82  ? 1.536   14.681  -91.567  1.00 26.65  ? 75   THR C CB  1 
ATOM   7671  O OG1 . THR C 1 82  ? 0.605   14.128  -92.497  1.00 26.67  ? 75   THR C OG1 1 
ATOM   7672  C CG2 . THR C 1 82  ? 2.928   14.643  -92.154  1.00 27.63  ? 75   THR C CG2 1 
ATOM   7673  N N   . LEU C 1 83  ? -0.105  15.220  -88.947  1.00 30.81  ? 76   LEU C N   1 
ATOM   7674  C CA  . LEU C 1 83  ? -1.357  15.692  -88.316  1.00 33.12  ? 76   LEU C CA  1 
ATOM   7675  C C   . LEU C 1 83  ? -1.750  17.023  -88.941  1.00 32.95  ? 76   LEU C C   1 
ATOM   7676  O O   . LEU C 1 83  ? -0.841  17.842  -89.226  1.00 29.01  ? 76   LEU C O   1 
ATOM   7677  C CB  . LEU C 1 83  ? -1.122  15.865  -86.814  1.00 34.91  ? 76   LEU C CB  1 
ATOM   7678  C CG  . LEU C 1 83  ? -1.030  14.556  -86.046  1.00 36.03  ? 76   LEU C CG  1 
ATOM   7679  C CD1 . LEU C 1 83  ? -0.886  14.829  -84.569  1.00 38.07  ? 76   LEU C CD1 1 
ATOM   7680  C CD2 . LEU C 1 83  ? -2.255  13.679  -86.309  1.00 36.59  ? 76   LEU C CD2 1 
ATOM   7681  N N   . VAL C 1 84  ? -3.058  17.221  -89.099  1.00 31.44  ? 77   VAL C N   1 
ATOM   7682  C CA  . VAL C 1 84  ? -3.609  18.463  -89.695  1.00 31.38  ? 77   VAL C CA  1 
ATOM   7683  C C   . VAL C 1 84  ? -4.521  19.118  -88.661  1.00 30.21  ? 77   VAL C C   1 
ATOM   7684  O O   . VAL C 1 84  ? -5.416  18.415  -88.141  1.00 30.82  ? 77   VAL C O   1 
ATOM   7685  C CB  . VAL C 1 84  ? -4.331  18.144  -91.012  1.00 31.93  ? 77   VAL C CB  1 
ATOM   7686  C CG1 . VAL C 1 84  ? -4.828  19.412  -91.675  1.00 33.19  ? 77   VAL C CG1 1 
ATOM   7687  C CG2 . VAL C 1 84  ? -3.435  17.353  -91.952  1.00 31.05  ? 77   VAL C CG2 1 
ATOM   7688  N N   . ASP C 1 85  ? -4.284  20.401  -88.371  1.00 30.33  ? 78   ASP C N   1 
ATOM   7689  C CA  . ASP C 1 85  ? -5.151  21.217  -87.484  1.00 32.61  ? 78   ASP C CA  1 
ATOM   7690  C C   . ASP C 1 85  ? -6.344  21.742  -88.289  1.00 34.53  ? 78   ASP C C   1 
ATOM   7691  O O   . ASP C 1 85  ? -6.427  21.484  -89.511  1.00 31.32  ? 78   ASP C O   1 
ATOM   7692  C CB  . ASP C 1 85  ? -4.380  22.331  -86.765  1.00 34.30  ? 78   ASP C CB  1 
ATOM   7693  C CG  . ASP C 1 85  ? -3.965  23.533  -87.599  1.00 36.27  ? 78   ASP C CG  1 
ATOM   7694  O OD1 . ASP C 1 85  ? -4.410  23.628  -88.763  1.00 38.26  ? 78   ASP C OD1 1 
ATOM   7695  O OD2 . ASP C 1 85  ? -3.173  24.371  -87.076  1.00 36.02  ? 78   ASP C OD2 1 
ATOM   7696  N N   . THR C 1 86  ? -7.226  22.458  -87.597  1.00 37.09  ? 79   THR C N   1 
ATOM   7697  C CA  . THR C 1 86  ? -8.494  23.027  -88.123  1.00 37.51  ? 79   THR C CA  1 
ATOM   7698  C C   . THR C 1 86  ? -8.212  24.095  -89.192  1.00 38.50  ? 79   THR C C   1 
ATOM   7699  O O   . THR C 1 86  ? -9.151  24.395  -89.954  1.00 36.06  ? 79   THR C O   1 
ATOM   7700  C CB  . THR C 1 86  ? -9.322  23.582  -86.957  1.00 35.34  ? 79   THR C CB  1 
ATOM   7701  O OG1 . THR C 1 86  ? -8.489  24.465  -86.202  1.00 33.35  ? 79   THR C OG1 1 
ATOM   7702  C CG2 . THR C 1 86  ? -9.873  22.486  -86.072  1.00 33.90  ? 79   THR C CG2 1 
ATOM   7703  N N   . GLN C 1 87  ? -6.989  24.650  -89.242  1.00 40.78  ? 80   GLN C N   1 
ATOM   7704  C CA  . GLN C 1 87  ? -6.596  25.708  -90.214  1.00 42.07  ? 80   GLN C CA  1 
ATOM   7705  C C   . GLN C 1 87  ? -5.899  25.089  -91.432  1.00 41.16  ? 80   GLN C C   1 
ATOM   7706  O O   . GLN C 1 87  ? -5.441  25.864  -92.313  1.00 37.76  ? 80   GLN C O   1 
ATOM   7707  C CB  . GLN C 1 87  ? -5.681  26.730  -89.548  1.00 42.72  ? 80   GLN C CB  1 
ATOM   7708  C CG  . GLN C 1 87  ? -6.266  27.292  -88.268  1.00 47.69  ? 80   GLN C CG  1 
ATOM   7709  C CD  . GLN C 1 87  ? -5.245  28.143  -87.560  1.00 57.47  ? 80   GLN C CD  1 
ATOM   7710  O OE1 . GLN C 1 87  ? -4.565  28.959  -88.181  1.00 64.92  ? 80   GLN C OE1 1 
ATOM   7711  N NE2 . GLN C 1 87  ? -5.093  27.913  -86.264  1.00 62.09  ? 80   GLN C NE2 1 
ATOM   7712  N N   . GLY C 1 88  ? -5.807  23.754  -91.474  1.00 39.82  ? 81   GLY C N   1 
ATOM   7713  C CA  . GLY C 1 88  ? -5.221  22.993  -92.595  1.00 37.25  ? 81   GLY C CA  1 
ATOM   7714  C C   . GLY C 1 88  ? -3.709  22.883  -92.506  1.00 35.37  ? 81   GLY C C   1 
ATOM   7715  O O   . GLY C 1 88  ? -3.106  22.406  -93.475  1.00 31.82  ? 81   GLY C O   1 
ATOM   7716  N N   . GLN C 1 89  ? -3.104  23.314  -91.396  1.00 35.66  ? 82   GLN C N   1 
ATOM   7717  C CA  . GLN C 1 89  ? -1.633  23.277  -91.222  1.00 38.18  ? 82   GLN C CA  1 
ATOM   7718  C C   . GLN C 1 89  ? -1.240  21.837  -90.876  1.00 35.12  ? 82   GLN C C   1 
ATOM   7719  O O   . GLN C 1 89  ? -1.832  21.271  -89.945  1.00 34.85  ? 82   GLN C O   1 
ATOM   7720  C CB  . GLN C 1 89  ? -1.195  24.343  -90.232  1.00 43.44  ? 82   GLN C CB  1 
ATOM   7721  C CG  . GLN C 1 89  ? -1.262  25.743  -90.826  1.00 49.65  ? 82   GLN C CG  1 
ATOM   7722  C CD  . GLN C 1 89  ? -1.408  26.791  -89.759  1.00 59.70  ? 82   GLN C CD  1 
ATOM   7723  O OE1 . GLN C 1 89  ? -1.230  27.981  -90.015  1.00 69.52  ? 82   GLN C OE1 1 
ATOM   7724  N NE2 . GLN C 1 89  ? -1.735  26.342  -88.557  1.00 66.01  ? 82   GLN C NE2 1 
ATOM   7725  N N   . GLU C 1 90  ? -0.330  21.264  -91.668  1.00 34.05  ? 83   GLU C N   1 
ATOM   7726  C CA  . GLU C 1 90  ? 0.129   19.851  -91.584  1.00 35.53  ? 83   GLU C CA  1 
ATOM   7727  C C   . GLU C 1 90  ? 1.413   19.831  -90.741  1.00 32.09  ? 83   GLU C C   1 
ATOM   7728  O O   . GLU C 1 90  ? 2.287   20.667  -90.976  1.00 32.72  ? 83   GLU C O   1 
ATOM   7729  C CB  . GLU C 1 90  ? 0.337   19.261  -92.990  1.00 37.74  ? 83   GLU C CB  1 
ATOM   7730  C CG  . GLU C 1 90  ? 0.458   17.738  -93.020  1.00 40.48  ? 83   GLU C CG  1 
ATOM   7731  C CD  . GLU C 1 90  ? 0.483   17.066  -94.396  1.00 43.70  ? 83   GLU C CD  1 
ATOM   7732  O OE1 . GLU C 1 90  ? 1.090   17.636  -95.320  1.00 49.66  ? 83   GLU C OE1 1 
ATOM   7733  O OE2 . GLU C 1 90  ? -0.113  15.987  -94.571  1.00 42.44  ? 83   GLU C OE2 1 
ATOM   7734  N N   . PHE C 1 91  ? 1.485   18.944  -89.754  1.00 29.46  ? 84   PHE C N   1 
ATOM   7735  C CA  . PHE C 1 91  ? 2.635   18.795  -88.834  1.00 28.36  ? 84   PHE C CA  1 
ATOM   7736  C C   . PHE C 1 91  ? 3.258   17.438  -89.096  1.00 26.20  ? 84   PHE C C   1 
ATOM   7737  O O   . PHE C 1 91  ? 2.509   16.475  -89.227  1.00 23.35  ? 84   PHE C O   1 
ATOM   7738  C CB  . PHE C 1 91  ? 2.187   18.865  -87.374  1.00 30.13  ? 84   PHE C CB  1 
ATOM   7739  C CG  . PHE C 1 91  ? 1.691   20.225  -86.956  1.00 30.98  ? 84   PHE C CG  1 
ATOM   7740  C CD1 . PHE C 1 91  ? 0.426   20.654  -87.307  1.00 31.66  ? 84   PHE C CD1 1 
ATOM   7741  C CD2 . PHE C 1 91  ? 2.517   21.100  -86.272  1.00 31.62  ? 84   PHE C CD2 1 
ATOM   7742  C CE1 . PHE C 1 91  ? -0.015  21.919  -86.951  1.00 31.75  ? 84   PHE C CE1 1 
ATOM   7743  C CE2 . PHE C 1 91  ? 2.073   22.361  -85.905  1.00 31.61  ? 84   PHE C CE2 1 
ATOM   7744  C CZ  . PHE C 1 91  ? 0.810   22.773  -86.258  1.00 30.27  ? 84   PHE C CZ  1 
ATOM   7745  N N   . ILE C 1 92  ? 4.579   17.375  -89.176  1.00 26.59  ? 85   ILE C N   1 
ATOM   7746  C CA  . ILE C 1 92  ? 5.303   16.081  -89.076  1.00 27.72  ? 85   ILE C CA  1 
ATOM   7747  C C   . ILE C 1 92  ? 5.265   15.698  -87.603  1.00 29.35  ? 85   ILE C C   1 
ATOM   7748  O O   . ILE C 1 92  ? 5.527   16.585  -86.761  1.00 32.27  ? 85   ILE C O   1 
ATOM   7749  C CB  . ILE C 1 92  ? 6.735   16.191  -89.631  1.00 28.23  ? 85   ILE C CB  1 
ATOM   7750  C CG1 . ILE C 1 92  ? 6.719   16.396  -91.149  1.00 28.25  ? 85   ILE C CG1 1 
ATOM   7751  C CG2 . ILE C 1 92  ? 7.575   14.986  -89.230  1.00 27.72  ? 85   ILE C CG2 1 
ATOM   7752  C CD1 . ILE C 1 92  ? 7.968   17.039  -91.683  1.00 27.81  ? 85   ILE C CD1 1 
ATOM   7753  N N   . ASP C 1 93  ? 4.918   14.447  -87.311  1.00 30.09  ? 86   ASP C N   1 
ATOM   7754  C CA  . ASP C 1 93  ? 4.679   13.977  -85.924  1.00 31.79  ? 86   ASP C CA  1 
ATOM   7755  C C   . ASP C 1 93  ? 5.931   13.298  -85.368  1.00 32.49  ? 86   ASP C C   1 
ATOM   7756  O O   . ASP C 1 93  ? 6.134   12.123  -85.675  1.00 38.80  ? 86   ASP C O   1 
ATOM   7757  C CB  . ASP C 1 93  ? 3.465   13.051  -85.856  1.00 32.05  ? 86   ASP C CB  1 
ATOM   7758  C CG  . ASP C 1 93  ? 3.055   12.762  -84.425  1.00 31.19  ? 86   ASP C CG  1 
ATOM   7759  O OD1 . ASP C 1 93  ? 3.763   13.225  -83.502  1.00 30.26  ? 86   ASP C OD1 1 
ATOM   7760  O OD2 . ASP C 1 93  ? 2.038   12.072  -84.242  1.00 29.15  ? 86   ASP C OD2 1 
ATOM   7761  N N   . CYS C 1 94  ? 6.696   14.011  -84.541  1.00 31.92  ? 87   CYS C N   1 
ATOM   7762  C CA  . CYS C 1 94  ? 7.827   13.467  -83.743  1.00 31.66  ? 87   CYS C CA  1 
ATOM   7763  C C   . CYS C 1 94  ? 7.466   13.295  -82.261  1.00 30.37  ? 87   CYS C C   1 
ATOM   7764  O O   . CYS C 1 94  ? 8.370   12.964  -81.469  1.00 31.73  ? 87   CYS C O   1 
ATOM   7765  C CB  . CYS C 1 94  ? 9.014   14.397  -83.838  1.00 33.96  ? 87   CYS C CB  1 
ATOM   7766  S SG  . CYS C 1 94  ? 9.796   14.255  -85.443  1.00 36.82  ? 87   CYS C SG  1 
ATOM   7767  N N   . LEU C 1 95  ? 6.214   13.542  -81.908  1.00 28.90  ? 88   LEU C N   1 
ATOM   7768  C CA  . LEU C 1 95  ? 5.652   13.240  -80.578  1.00 29.96  ? 88   LEU C CA  1 
ATOM   7769  C C   . LEU C 1 95  ? 5.152   11.789  -80.561  1.00 29.41  ? 88   LEU C C   1 
ATOM   7770  O O   . LEU C 1 95  ? 5.364   11.100  -79.550  1.00 28.26  ? 88   LEU C O   1 
ATOM   7771  C CB  . LEU C 1 95  ? 4.531   14.248  -80.312  1.00 30.94  ? 88   LEU C CB  1 
ATOM   7772  C CG  . LEU C 1 95  ? 3.880   14.159  -78.940  1.00 32.85  ? 88   LEU C CG  1 
ATOM   7773  C CD1 . LEU C 1 95  ? 4.936   14.085  -77.849  1.00 34.86  ? 88   LEU C CD1 1 
ATOM   7774  C CD2 . LEU C 1 95  ? 2.957   15.341  -78.717  1.00 33.04  ? 88   LEU C CD2 1 
ATOM   7775  N N   . GLY C 1 96  ? 4.530   11.342  -81.657  1.00 31.47  ? 89   GLY C N   1 
ATOM   7776  C CA  . GLY C 1 96  ? 3.932   9.997   -81.812  1.00 31.64  ? 89   GLY C CA  1 
ATOM   7777  C C   . GLY C 1 96  ? 2.882   9.703   -80.743  1.00 31.09  ? 89   GLY C C   1 
ATOM   7778  O O   . GLY C 1 96  ? 2.725   8.522   -80.351  1.00 32.71  ? 89   GLY C O   1 
ATOM   7779  N N   . GLY C 1 97  ? 2.165   10.728  -80.283  1.00 28.52  ? 90   GLY C N   1 
ATOM   7780  C CA  . GLY C 1 97  ? 1.241   10.606  -79.143  1.00 30.09  ? 90   GLY C CA  1 
ATOM   7781  C C   . GLY C 1 97  ? 1.922   9.919   -77.973  1.00 31.66  ? 90   GLY C C   1 
ATOM   7782  O O   . GLY C 1 97  ? 1.286   9.095   -77.311  1.00 35.80  ? 90   GLY C O   1 
ATOM   7783  N N   . PHE C 1 98  ? 3.193   10.227  -77.729  1.00 30.58  ? 91   PHE C N   1 
ATOM   7784  C CA  . PHE C 1 98  ? 3.961   9.705   -76.573  1.00 31.52  ? 91   PHE C CA  1 
ATOM   7785  C C   . PHE C 1 98  ? 4.159   8.186   -76.722  1.00 28.66  ? 91   PHE C C   1 
ATOM   7786  O O   . PHE C 1 98  ? 4.253   7.491   -75.694  1.00 29.61  ? 91   PHE C O   1 
ATOM   7787  C CB  . PHE C 1 98  ? 3.257   10.124  -75.274  1.00 33.51  ? 91   PHE C CB  1 
ATOM   7788  C CG  . PHE C 1 98  ? 3.164   11.618  -75.060  1.00 34.16  ? 91   PHE C CG  1 
ATOM   7789  C CD1 . PHE C 1 98  ? 4.199   12.313  -74.451  1.00 33.14  ? 91   PHE C CD1 1 
ATOM   7790  C CD2 . PHE C 1 98  ? 2.064   12.343  -75.501  1.00 34.82  ? 91   PHE C CD2 1 
ATOM   7791  C CE1 . PHE C 1 98  ? 4.133   13.686  -74.267  1.00 33.66  ? 91   PHE C CE1 1 
ATOM   7792  C CE2 . PHE C 1 98  ? 1.998   13.719  -75.314  1.00 34.96  ? 91   PHE C CE2 1 
ATOM   7793  C CZ  . PHE C 1 98  ? 3.027   14.386  -74.688  1.00 34.20  ? 91   PHE C CZ  1 
ATOM   7794  N N   . GLY C 1 99  ? 4.250   7.693   -77.958  1.00 26.15  ? 92   GLY C N   1 
ATOM   7795  C CA  . GLY C 1 99  ? 4.634   6.302   -78.278  1.00 26.06  ? 92   GLY C CA  1 
ATOM   7796  C C   . GLY C 1 99  ? 3.445   5.436   -78.640  1.00 25.11  ? 92   GLY C C   1 
ATOM   7797  O O   . GLY C 1 99  ? 3.555   4.211   -78.523  1.00 25.41  ? 92   GLY C O   1 
ATOM   7798  N N   . ILE C 1 100 ? 2.364   6.044   -79.107  1.00 25.24  ? 93   ILE C N   1 
ATOM   7799  C CA  . ILE C 1 100 ? 1.132   5.326   -79.532  1.00 27.79  ? 93   ILE C CA  1 
ATOM   7800  C C   . ILE C 1 100 ? 1.220   4.962   -81.013  1.00 26.21  ? 93   ILE C C   1 
ATOM   7801  O O   . ILE C 1 100 ? 0.849   3.830   -81.367  1.00 25.33  ? 93   ILE C O   1 
ATOM   7802  C CB  . ILE C 1 100 ? -0.088  6.223   -79.279  1.00 28.94  ? 93   ILE C CB  1 
ATOM   7803  C CG1 . ILE C 1 100 ? -0.227  6.565   -77.797  1.00 32.04  ? 93   ILE C CG1 1 
ATOM   7804  C CG2 . ILE C 1 100 ? -1.344  5.586   -79.820  1.00 26.70  ? 93   ILE C CG2 1 
ATOM   7805  C CD1 . ILE C 1 100 ? -1.211  7.694   -77.573  1.00 34.80  ? 93   ILE C CD1 1 
ATOM   7806  N N   . PHE C 1 101 ? 1.638   5.922   -81.839  1.00 25.42  ? 94   PHE C N   1 
ATOM   7807  C CA  . PHE C 1 101 ? 1.485   5.908   -83.315  1.00 25.22  ? 94   PHE C CA  1 
ATOM   7808  C C   . PHE C 1 101 ? 2.707   5.234   -83.958  1.00 25.39  ? 94   PHE C C   1 
ATOM   7809  O O   . PHE C 1 101 ? 3.295   5.830   -84.877  1.00 27.70  ? 94   PHE C O   1 
ATOM   7810  C CB  . PHE C 1 101 ? 1.258   7.334   -83.821  1.00 25.21  ? 94   PHE C CB  1 
ATOM   7811  C CG  . PHE C 1 101 ? 0.016   7.996   -83.277  1.00 26.50  ? 94   PHE C CG  1 
ATOM   7812  C CD1 . PHE C 1 101 ? -1.246  7.495   -83.573  1.00 26.99  ? 94   PHE C CD1 1 
ATOM   7813  C CD2 . PHE C 1 101 ? 0.100   9.124   -82.477  1.00 26.35  ? 94   PHE C CD2 1 
ATOM   7814  C CE1 . PHE C 1 101 ? -2.387  8.109   -83.088  1.00 25.72  ? 94   PHE C CE1 1 
ATOM   7815  C CE2 . PHE C 1 101 ? -1.042  9.721   -81.960  1.00 27.41  ? 94   PHE C CE2 1 
ATOM   7816  C CZ  . PHE C 1 101 ? -2.280  9.222   -82.281  1.00 27.51  ? 94   PHE C CZ  1 
ATOM   7817  N N   . ASN C 1 102 ? 3.039   4.011   -83.517  1.00 24.67  ? 95   ASN C N   1 
ATOM   7818  C CA  . ASN C 1 102 ? 4.217   3.224   -83.978  1.00 23.59  ? 95   ASN C CA  1 
ATOM   7819  C C   . ASN C 1 102 ? 4.033   2.883   -85.452  1.00 23.76  ? 95   ASN C C   1 
ATOM   7820  O O   . ASN C 1 102 ? 5.046   2.949   -86.208  1.00 22.22  ? 95   ASN C O   1 
ATOM   7821  C CB  . ASN C 1 102 ? 4.424   1.948   -83.165  1.00 23.42  ? 95   ASN C CB  1 
ATOM   7822  C CG  . ASN C 1 102 ? 5.075   2.227   -81.828  1.00 22.18  ? 95   ASN C CG  1 
ATOM   7823  O OD1 . ASN C 1 102 ? 5.035   3.354   -81.338  1.00 19.94  ? 95   ASN C OD1 1 
ATOM   7824  N ND2 . ASN C 1 102 ? 5.694   1.216   -81.245  1.00 22.90  ? 95   ASN C ND2 1 
ATOM   7825  N N   . VAL C 1 103 ? 2.794   2.574   -85.850  1.00 21.16  ? 96   VAL C N   1 
ATOM   7826  C CA  . VAL C 1 103 ? 2.486   2.174   -87.252  1.00 20.62  ? 96   VAL C CA  1 
ATOM   7827  C C   . VAL C 1 103 ? 1.791   3.337   -87.971  1.00 20.18  ? 96   VAL C C   1 
ATOM   7828  O O   . VAL C 1 103 ? 1.153   3.096   -88.992  1.00 18.41  ? 96   VAL C O   1 
ATOM   7829  C CB  . VAL C 1 103 ? 1.675   0.869   -87.288  1.00 20.36  ? 96   VAL C CB  1 
ATOM   7830  C CG1 . VAL C 1 103 ? 2.475   -0.279  -86.701  1.00 20.21  ? 96   VAL C CG1 1 
ATOM   7831  C CG2 . VAL C 1 103 ? 0.327   1.002   -86.591  1.00 20.74  ? 96   VAL C CG2 1 
ATOM   7832  N N   . GLY C 1 104 ? 1.963   4.558   -87.470  1.00 20.20  ? 97   GLY C N   1 
ATOM   7833  C CA  . GLY C 1 104 ? 1.479   5.782   -88.122  1.00 20.52  ? 97   GLY C CA  1 
ATOM   7834  C C   . GLY C 1 104 ? 0.039   6.084   -87.761  1.00 21.24  ? 97   GLY C C   1 
ATOM   7835  O O   . GLY C 1 104 ? -0.574  5.323   -86.983  1.00 20.08  ? 97   GLY C O   1 
ATOM   7836  N N   . HIS C 1 105 ? -0.462  7.180   -88.326  1.00 22.61  ? 98   HIS C N   1 
ATOM   7837  C CA  . HIS C 1 105 ? -1.833  7.721   -88.157  1.00 24.39  ? 98   HIS C CA  1 
ATOM   7838  C C   . HIS C 1 105 ? -2.762  7.043   -89.168  1.00 23.24  ? 98   HIS C C   1 
ATOM   7839  O O   . HIS C 1 105 ? -2.432  7.049   -90.372  1.00 24.87  ? 98   HIS C O   1 
ATOM   7840  C CB  . HIS C 1 105 ? -1.829  9.252   -88.310  1.00 25.82  ? 98   HIS C CB  1 
ATOM   7841  C CG  . HIS C 1 105 ? -1.161  9.951   -87.181  1.00 26.19  ? 98   HIS C CG  1 
ATOM   7842  N ND1 . HIS C 1 105 ? -1.824  10.229  -86.015  1.00 28.31  ? 98   HIS C ND1 1 
ATOM   7843  C CD2 . HIS C 1 105 ? 0.102   10.409  -87.035  1.00 28.99  ? 98   HIS C CD2 1 
ATOM   7844  C CE1 . HIS C 1 105 ? -0.997  10.813  -85.169  1.00 28.63  ? 98   HIS C CE1 1 
ATOM   7845  N NE2 . HIS C 1 105 ? 0.195   10.951  -85.783  1.00 29.66  ? 98   HIS C NE2 1 
ATOM   7846  N N   . ARG C 1 106 ? -3.861  6.467   -88.680  1.00 22.87  ? 99   ARG C N   1 
ATOM   7847  C CA  . ARG C 1 106 ? -4.871  5.765   -89.504  1.00 23.55  ? 99   ARG C CA  1 
ATOM   7848  C C   . ARG C 1 106 ? -4.125  4.776   -90.398  1.00 22.15  ? 99   ARG C C   1 
ATOM   7849  O O   . ARG C 1 106 ? -4.246  4.874   -91.644  1.00 21.62  ? 99   ARG C O   1 
ATOM   7850  C CB  . ARG C 1 106 ? -5.693  6.767   -90.325  1.00 25.44  ? 99   ARG C CB  1 
ATOM   7851  C CG  . ARG C 1 106 ? -6.436  7.793   -89.488  1.00 25.76  ? 99   ARG C CG  1 
ATOM   7852  C CD  . ARG C 1 106 ? -7.509  8.558   -90.250  1.00 28.06  ? 99   ARG C CD  1 
ATOM   7853  N NE  . ARG C 1 106 ? -8.537  7.696   -90.827  1.00 28.66  ? 99   ARG C NE  1 
ATOM   7854  C CZ  . ARG C 1 106 ? -8.605  7.338   -92.108  1.00 29.96  ? 99   ARG C CZ  1 
ATOM   7855  N NH1 . ARG C 1 106 ? -7.712  7.779   -92.975  1.00 31.32  ? 99   ARG C NH1 1 
ATOM   7856  N NH2 . ARG C 1 106 ? -9.570  6.540   -92.530  1.00 30.57  ? 99   ARG C NH2 1 
ATOM   7857  N N   . ASN C 1 107 ? -3.334  3.890   -89.797  1.00 19.99  ? 100  ASN C N   1 
ATOM   7858  C CA  . ASN C 1 107 ? -2.695  2.818   -90.584  1.00 18.71  ? 100  ASN C CA  1 
ATOM   7859  C C   . ASN C 1 107 ? -3.825  2.039   -91.251  1.00 17.87  ? 100  ASN C C   1 
ATOM   7860  O O   . ASN C 1 107 ? -4.723  1.534   -90.590  1.00 16.97  ? 100  ASN C O   1 
ATOM   7861  C CB  . ASN C 1 107 ? -1.787  1.941   -89.745  1.00 18.08  ? 100  ASN C CB  1 
ATOM   7862  C CG  . ASN C 1 107 ? -1.113  0.898   -90.602  1.00 19.12  ? 100  ASN C CG  1 
ATOM   7863  O OD1 . ASN C 1 107 ? -1.792  0.026   -91.122  1.00 20.66  ? 100  ASN C OD1 1 
ATOM   7864  N ND2 . ASN C 1 107 ? 0.197   0.992   -90.779  1.00 19.52  ? 100  ASN C ND2 1 
ATOM   7865  N N   . PRO C 1 108 ? -3.841  1.960   -92.591  1.00 17.47  ? 101  PRO C N   1 
ATOM   7866  C CA  . PRO C 1 108 ? -4.992  1.433   -93.305  1.00 18.65  ? 101  PRO C CA  1 
ATOM   7867  C C   . PRO C 1 108 ? -5.331  0.002   -92.870  1.00 18.75  ? 101  PRO C C   1 
ATOM   7868  O O   . PRO C 1 108 ? -6.513  -0.341  -92.890  1.00 20.40  ? 101  PRO C O   1 
ATOM   7869  C CB  . PRO C 1 108 ? -4.572  1.483   -94.784  1.00 18.38  ? 101  PRO C CB  1 
ATOM   7870  C CG  . PRO C 1 108 ? -3.466  2.506   -94.840  1.00 17.98  ? 101  PRO C CG  1 
ATOM   7871  C CD  . PRO C 1 108 ? -2.774  2.386   -93.501  1.00 18.61  ? 101  PRO C CD  1 
ATOM   7872  N N   . VAL C 1 109 ? -4.320  -0.797  -92.526  1.00 17.33  ? 102  VAL C N   1 
ATOM   7873  C CA  . VAL C 1 109 ? -4.529  -2.214  -92.106  1.00 18.19  ? 102  VAL C CA  1 
ATOM   7874  C C   . VAL C 1 109 ? -5.248  -2.222  -90.748  1.00 19.10  ? 102  VAL C C   1 
ATOM   7875  O O   . VAL C 1 109 ? -6.135  -3.069  -90.545  1.00 18.87  ? 102  VAL C O   1 
ATOM   7876  C CB  . VAL C 1 109 ? -3.188  -2.972  -92.031  1.00 19.21  ? 102  VAL C CB  1 
ATOM   7877  C CG1 . VAL C 1 109 ? -3.312  -4.311  -91.288  1.00 18.18  ? 102  VAL C CG1 1 
ATOM   7878  C CG2 . VAL C 1 109 ? -2.546  -3.123  -93.420  1.00 17.94  ? 102  VAL C CG2 1 
ATOM   7879  N N   . VAL C 1 110 ? -4.876  -1.316  -89.846  1.00 18.84  ? 103  VAL C N   1 
ATOM   7880  C CA  . VAL C 1 110 ? -5.493  -1.235  -88.494  1.00 18.94  ? 103  VAL C CA  1 
ATOM   7881  C C   . VAL C 1 110 ? -6.899  -0.656  -88.676  1.00 18.54  ? 103  VAL C C   1 
ATOM   7882  O O   . VAL C 1 110 ? -7.862  -1.247  -88.163  1.00 19.76  ? 103  VAL C O   1 
ATOM   7883  C CB  . VAL C 1 110 ? -4.653  -0.411  -87.505  1.00 18.47  ? 103  VAL C CB  1 
ATOM   7884  C CG1 . VAL C 1 110 ? -5.298  -0.386  -86.135  1.00 19.10  ? 103  VAL C CG1 1 
ATOM   7885  C CG2 . VAL C 1 110 ? -3.231  -0.922  -87.392  1.00 19.55  ? 103  VAL C CG2 1 
ATOM   7886  N N   . VAL C 1 111 ? -7.014  0.452   -89.396  1.00 17.98  ? 104  VAL C N   1 
ATOM   7887  C CA  . VAL C 1 111 ? -8.327  1.112   -89.592  1.00 18.58  ? 104  VAL C CA  1 
ATOM   7888  C C   . VAL C 1 111 ? -9.276  0.053   -90.153  1.00 18.12  ? 104  VAL C C   1 
ATOM   7889  O O   . VAL C 1 111 ? -10.396 -0.076  -89.628  1.00 17.55  ? 104  VAL C O   1 
ATOM   7890  C CB  . VAL C 1 111 ? -8.184  2.351   -90.484  1.00 19.40  ? 104  VAL C CB  1 
ATOM   7891  C CG1 . VAL C 1 111 ? -9.531  2.846   -90.998  1.00 20.56  ? 104  VAL C CG1 1 
ATOM   7892  C CG2 . VAL C 1 111 ? -7.448  3.443   -89.729  1.00 18.67  ? 104  VAL C CG2 1 
ATOM   7893  N N   . SER C 1 112 ? -8.796  -0.732  -91.119  1.00 17.82  ? 105  SER C N   1 
ATOM   7894  C CA  . SER C 1 112 ? -9.589  -1.786  -91.800  1.00 18.61  ? 105  SER C CA  1 
ATOM   7895  C C   . SER C 1 112 ? -10.099 -2.812  -90.797  1.00 17.49  ? 105  SER C C   1 
ATOM   7896  O O   . SER C 1 112 ? -11.255 -3.167  -90.862  1.00 16.37  ? 105  SER C O   1 
ATOM   7897  C CB  . SER C 1 112 ? -8.784  -2.463  -92.869  1.00 20.59  ? 105  SER C CB  1 
ATOM   7898  O OG  . SER C 1 112 ? -9.461  -3.601  -93.377  1.00 22.14  ? 105  SER C OG  1 
ATOM   7899  N N   . ALA C 1 113 ? -9.230  -3.311  -89.932  1.00 18.09  ? 106  ALA C N   1 
ATOM   7900  C CA  . ALA C 1 113 ? -9.571  -4.382  -88.967  1.00 18.06  ? 106  ALA C CA  1 
ATOM   7901  C C   . ALA C 1 113 ? -10.651 -3.867  -88.018  1.00 17.06  ? 106  ALA C C   1 
ATOM   7902  O O   . ALA C 1 113 ? -11.644 -4.603  -87.772  1.00 17.00  ? 106  ALA C O   1 
ATOM   7903  C CB  . ALA C 1 113 ? -8.344  -4.822  -88.227  1.00 18.04  ? 106  ALA C CB  1 
ATOM   7904  N N   . VAL C 1 114 ? -10.495 -2.623  -87.571  1.00 16.00  ? 107  VAL C N   1 
ATOM   7905  C CA  . VAL C 1 114 ? -11.448 -1.981  -86.626  1.00 16.75  ? 107  VAL C CA  1 
ATOM   7906  C C   . VAL C 1 114 ? -12.811 -1.816  -87.327  1.00 16.78  ? 107  VAL C C   1 
ATOM   7907  O O   . VAL C 1 114 ? -13.846 -2.298  -86.787  1.00 15.07  ? 107  VAL C O   1 
ATOM   7908  C CB  . VAL C 1 114 ? -10.851 -0.677  -86.066  1.00 16.44  ? 107  VAL C CB  1 
ATOM   7909  C CG1 . VAL C 1 114 ? -11.880 0.169   -85.326  1.00 16.34  ? 107  VAL C CG1 1 
ATOM   7910  C CG2 . VAL C 1 114 ? -9.662  -0.991  -85.162  1.00 16.18  ? 107  VAL C CG2 1 
ATOM   7911  N N   A GLN C 1 115 ? -12.810 -1.177  -88.501  0.60 18.24  ? 108  GLN C N   1 
ATOM   7912  N N   B GLN C 1 115 ? -12.811 -1.181  -88.504  0.40 17.01  ? 108  GLN C N   1 
ATOM   7913  C CA  A GLN C 1 115 ? -14.013 -0.999  -89.363  0.60 18.52  ? 108  GLN C CA  1 
ATOM   7914  C CA  B GLN C 1 115 ? -14.013 -0.999  -89.366  0.40 16.86  ? 108  GLN C CA  1 
ATOM   7915  C C   A GLN C 1 115 ? -14.744 -2.335  -89.521  0.60 17.82  ? 108  GLN C C   1 
ATOM   7916  C C   B GLN C 1 115 ? -14.745 -2.335  -89.524  0.40 16.97  ? 108  GLN C C   1 
ATOM   7917  O O   A GLN C 1 115 ? -15.980 -2.345  -89.366  0.60 17.40  ? 108  GLN C O   1 
ATOM   7918  O O   B GLN C 1 115 ? -15.982 -2.349  -89.366  0.40 16.75  ? 108  GLN C O   1 
ATOM   7919  C CB  A GLN C 1 115 ? -13.621 -0.497  -90.749  0.60 20.43  ? 108  GLN C CB  1 
ATOM   7920  C CB  B GLN C 1 115 ? -13.609 -0.478  -90.742  0.40 17.11  ? 108  GLN C CB  1 
ATOM   7921  C CG  A GLN C 1 115 ? -13.439 1.007   -90.846  0.60 21.99  ? 108  GLN C CG  1 
ATOM   7922  C CG  B GLN C 1 115 ? -14.764 0.108   -91.536  0.40 16.98  ? 108  GLN C CG  1 
ATOM   7923  C CD  A GLN C 1 115 ? -13.097 1.411   -92.263  0.60 22.76  ? 108  GLN C CD  1 
ATOM   7924  C CD  B GLN C 1 115 ? -15.332 1.326   -90.855  0.40 17.14  ? 108  GLN C CD  1 
ATOM   7925  O OE1 A GLN C 1 115 ? -12.439 0.672   -92.992  0.60 23.06  ? 108  GLN C OE1 1 
ATOM   7926  O OE1 B GLN C 1 115 ? -16.101 1.224   -89.900  0.40 18.11  ? 108  GLN C OE1 1 
ATOM   7927  N NE2 A GLN C 1 115 ? -13.614 2.555   -92.698  0.60 22.80  ? 108  GLN C NE2 1 
ATOM   7928  N NE2 B GLN C 1 115 ? -14.960 2.494   -91.352  0.40 16.83  ? 108  GLN C NE2 1 
ATOM   7929  N N   . ASN C 1 116 ? -13.999 -3.406  -89.819  1.00 17.35  ? 109  ASN C N   1 
ATOM   7930  C CA  . ASN C 1 116 ? -14.552 -4.761  -90.092  1.00 18.09  ? 109  ASN C CA  1 
ATOM   7931  C C   . ASN C 1 116 ? -15.231 -5.311  -88.839  1.00 19.40  ? 109  ASN C C   1 
ATOM   7932  O O   . ASN C 1 116 ? -16.386 -5.821  -88.965  1.00 20.95  ? 109  ASN C O   1 
ATOM   7933  C CB  . ASN C 1 116 ? -13.486 -5.743  -90.593  1.00 18.62  ? 109  ASN C CB  1 
ATOM   7934  C CG  . ASN C 1 116 ? -13.239 -5.672  -92.090  1.00 17.96  ? 109  ASN C CG  1 
ATOM   7935  O OD1 . ASN C 1 116 ? -14.164 -5.507  -92.878  1.00 20.81  ? 109  ASN C OD1 1 
ATOM   7936  N ND2 . ASN C 1 116 ? -12.004 -5.812  -92.513  1.00 17.41  ? 109  ASN C ND2 1 
ATOM   7937  N N   . GLN C 1 117 ? -14.579 -5.186  -87.674  1.00 19.03  ? 110  GLN C N   1 
ATOM   7938  C CA  . GLN C 1 117 ? -15.132 -5.719  -86.401  1.00 18.32  ? 110  GLN C CA  1 
ATOM   7939  C C   . GLN C 1 117 ? -16.308 -4.850  -85.964  1.00 18.50  ? 110  GLN C C   1 
ATOM   7940  O O   . GLN C 1 117 ? -17.298 -5.411  -85.465  1.00 20.35  ? 110  GLN C O   1 
ATOM   7941  C CB  . GLN C 1 117 ? -14.043 -5.803  -85.332  1.00 18.62  ? 110  GLN C CB  1 
ATOM   7942  C CG  . GLN C 1 117 ? -14.430 -6.656  -84.139  1.00 18.11  ? 110  GLN C CG  1 
ATOM   7943  C CD  . GLN C 1 117 ? -14.945 -8.021  -84.524  1.00 18.78  ? 110  GLN C CD  1 
ATOM   7944  O OE1 . GLN C 1 117 ? -14.416 -8.684  -85.389  1.00 20.96  ? 110  GLN C OE1 1 
ATOM   7945  N NE2 . GLN C 1 117 ? -16.000 -8.469  -83.874  1.00 20.51  ? 110  GLN C NE2 1 
ATOM   7946  N N   . LEU C 1 118 ? -16.218 -3.533  -86.144  1.00 18.35  ? 111  LEU C N   1 
ATOM   7947  C CA  . LEU C 1 118 ? -17.327 -2.589  -85.826  1.00 18.91  ? 111  LEU C CA  1 
ATOM   7948  C C   . LEU C 1 118 ? -18.604 -3.039  -86.539  1.00 18.52  ? 111  LEU C C   1 
ATOM   7949  O O   . LEU C 1 118 ? -19.673 -2.899  -85.965  1.00 19.15  ? 111  LEU C O   1 
ATOM   7950  C CB  . LEU C 1 118 ? -16.901 -1.173  -86.232  1.00 19.70  ? 111  LEU C CB  1 
ATOM   7951  C CG  . LEU C 1 118 ? -17.917 -0.056  -85.972  1.00 19.46  ? 111  LEU C CG  1 
ATOM   7952  C CD1 . LEU C 1 118 ? -18.343 -0.043  -84.509  1.00 18.81  ? 111  LEU C CD1 1 
ATOM   7953  C CD2 . LEU C 1 118 ? -17.355 1.306   -86.384  1.00 19.87  ? 111  LEU C CD2 1 
ATOM   7954  N N   . ALA C 1 119 ? -18.493 -3.594  -87.746  1.00 20.21  ? 112  ALA C N   1 
ATOM   7955  C CA  . ALA C 1 119 ? -19.644 -4.056  -88.548  1.00 19.88  ? 112  ALA C CA  1 
ATOM   7956  C C   . ALA C 1 119 ? -20.279 -5.314  -87.937  1.00 21.69  ? 112  ALA C C   1 
ATOM   7957  O O   . ALA C 1 119 ? -21.457 -5.568  -88.257  1.00 25.49  ? 112  ALA C O   1 
ATOM   7958  C CB  . ALA C 1 119 ? -19.215 -4.295  -89.962  1.00 19.96  ? 112  ALA C CB  1 
ATOM   7959  N N   . LYS C 1 120 ? -19.573 -6.065  -87.083  1.00 23.35  ? 113  LYS C N   1 
ATOM   7960  C CA  . LYS C 1 120 ? -20.083 -7.322  -86.458  1.00 23.24  ? 113  LYS C CA  1 
ATOM   7961  C C   . LYS C 1 120 ? -20.444 -7.113  -84.983  1.00 24.17  ? 113  LYS C C   1 
ATOM   7962  O O   . LYS C 1 120 ? -21.614 -7.365  -84.608  1.00 24.80  ? 113  LYS C O   1 
ATOM   7963  C CB  . LYS C 1 120 ? -19.034 -8.431  -86.494  1.00 25.22  ? 113  LYS C CB  1 
ATOM   7964  C CG  . LYS C 1 120 ? -18.737 -9.023  -87.859  1.00 26.03  ? 113  LYS C CG  1 
ATOM   7965  C CD  . LYS C 1 120 ? -18.152 -10.401 -87.804  1.00 25.91  ? 113  LYS C CD  1 
ATOM   7966  C CE  . LYS C 1 120 ? -16.653 -10.408 -87.891  1.00 28.54  ? 113  LYS C CE  1 
ATOM   7967  N NZ  . LYS C 1 120 ? -16.125 -11.767 -87.637  1.00 31.03  ? 113  LYS C NZ  1 
ATOM   7968  N N   . GLN C 1 121 ? -19.466 -6.742  -84.154  1.00 24.92  ? 114  GLN C N   1 
ATOM   7969  C CA  . GLN C 1 121 ? -19.593 -6.653  -82.671  1.00 23.78  ? 114  GLN C CA  1 
ATOM   7970  C C   . GLN C 1 121 ? -18.427 -5.842  -82.109  1.00 21.30  ? 114  GLN C C   1 
ATOM   7971  O O   . GLN C 1 121 ? -17.317 -6.359  -81.995  1.00 19.42  ? 114  GLN C O   1 
ATOM   7972  C CB  . GLN C 1 121 ? -19.599 -8.063  -82.082  1.00 26.72  ? 114  GLN C CB  1 
ATOM   7973  C CG  . GLN C 1 121 ? -20.309 -8.161  -80.751  1.00 31.65  ? 114  GLN C CG  1 
ATOM   7974  C CD  . GLN C 1 121 ? -19.864 -9.355  -79.939  1.00 37.55  ? 114  GLN C CD  1 
ATOM   7975  O OE1 . GLN C 1 121 ? -18.865 -10.014 -80.238  1.00 44.63  ? 114  GLN C OE1 1 
ATOM   7976  N NE2 . GLN C 1 121 ? -20.598 -9.628  -78.871  1.00 41.64  ? 114  GLN C NE2 1 
ATOM   7977  N N   . PRO C 1 122 ? -18.615 -4.542  -81.783  1.00 18.78  ? 115  PRO C N   1 
ATOM   7978  C CA  . PRO C 1 122 ? -17.532 -3.715  -81.255  1.00 19.18  ? 115  PRO C CA  1 
ATOM   7979  C C   . PRO C 1 122 ? -17.197 -4.014  -79.780  1.00 20.49  ? 115  PRO C C   1 
ATOM   7980  O O   . PRO C 1 122 ? -16.000 -4.068  -79.462  1.00 19.21  ? 115  PRO C O   1 
ATOM   7981  C CB  . PRO C 1 122 ? -18.057 -2.281  -81.437  1.00 18.35  ? 115  PRO C CB  1 
ATOM   7982  C CG  . PRO C 1 122 ? -19.537 -2.410  -81.366  1.00 17.67  ? 115  PRO C CG  1 
ATOM   7983  C CD  . PRO C 1 122 ? -19.846 -3.770  -81.951  1.00 17.94  ? 115  PRO C CD  1 
ATOM   7984  N N   . LEU C 1 123 ? -18.221 -4.177  -78.919  1.00 21.30  ? 116  LEU C N   1 
ATOM   7985  C CA  . LEU C 1 123 ? -18.034 -4.597  -77.503  1.00 21.32  ? 116  LEU C CA  1 
ATOM   7986  C C   . LEU C 1 123 ? -18.727 -5.937  -77.249  1.00 22.14  ? 116  LEU C C   1 
ATOM   7987  O O   . LEU C 1 123 ? -19.740 -6.222  -77.896  1.00 25.27  ? 116  LEU C O   1 
ATOM   7988  C CB  . LEU C 1 123 ? -18.564 -3.512  -76.572  1.00 21.67  ? 116  LEU C CB  1 
ATOM   7989  C CG  . LEU C 1 123 ? -17.823 -2.176  -76.632  1.00 22.25  ? 116  LEU C CG  1 
ATOM   7990  C CD1 . LEU C 1 123 ? -18.297 -1.250  -75.528  1.00 23.53  ? 116  LEU C CD1 1 
ATOM   7991  C CD2 . LEU C 1 123 ? -16.322 -2.360  -76.533  1.00 21.69  ? 116  LEU C CD2 1 
ATOM   7992  N N   . HIS C 1 124 ? -18.168 -6.728  -76.342  1.00 24.42  ? 117  HIS C N   1 
ATOM   7993  C CA  . HIS C 1 124 ? -18.546 -8.136  -76.039  1.00 27.22  ? 117  HIS C CA  1 
ATOM   7994  C C   . HIS C 1 124 ? -19.478 -8.171  -74.815  1.00 30.27  ? 117  HIS C C   1 
ATOM   7995  O O   . HIS C 1 124 ? -19.615 -7.126  -74.117  1.00 31.39  ? 117  HIS C O   1 
ATOM   7996  C CB  . HIS C 1 124 ? -17.282 -9.014  -75.875  1.00 27.89  ? 117  HIS C CB  1 
ATOM   7997  C CG  . HIS C 1 124 ? -16.399 -8.601  -74.749  1.00 27.84  ? 117  HIS C CG  1 
ATOM   7998  N ND1 . HIS C 1 124 ? -15.837 -7.347  -74.685  1.00 29.09  ? 117  HIS C ND1 1 
ATOM   7999  C CD2 . HIS C 1 124 ? -15.995 -9.240  -73.634  1.00 29.60  ? 117  HIS C CD2 1 
ATOM   8000  C CE1 . HIS C 1 124 ? -15.135 -7.217  -73.570  1.00 29.96  ? 117  HIS C CE1 1 
ATOM   8001  N NE2 . HIS C 1 124 ? -15.218 -8.362  -72.905  1.00 30.83  ? 117  HIS C NE2 1 
ATOM   8002  N N   . SER C 1 125 ? -20.090 -9.334  -74.567  1.00 33.48  ? 118  SER C N   1 
ATOM   8003  C CA  . SER C 1 125 ? -21.099 -9.596  -73.501  1.00 35.24  ? 118  SER C CA  1 
ATOM   8004  C C   . SER C 1 125 ? -20.397 -9.793  -72.159  1.00 36.62  ? 118  SER C C   1 
ATOM   8005  O O   . SER C 1 125 ? -20.993 -9.473  -71.129  1.00 33.64  ? 118  SER C O   1 
ATOM   8006  C CB  . SER C 1 125 ? -21.909 -10.814 -73.836  1.00 35.25  ? 118  SER C CB  1 
ATOM   8007  O OG  . SER C 1 125 ? -21.064 -11.957 -73.943  1.00 34.90  ? 118  SER C OG  1 
ATOM   8008  N N   . GLN C 1 126 ? -19.183 -10.346 -72.213  1.00 41.46  ? 119  GLN C N   1 
ATOM   8009  C CA  . GLN C 1 126 ? -18.364 -10.804 -71.064  1.00 41.84  ? 119  GLN C CA  1 
ATOM   8010  C C   . GLN C 1 126 ? -18.918 -12.115 -70.503  1.00 41.25  ? 119  GLN C C   1 
ATOM   8011  O O   . GLN C 1 126 ? -18.492 -12.492 -69.391  1.00 53.19  ? 119  GLN C O   1 
ATOM   8012  C CB  . GLN C 1 126 ? -18.316 -9.746  -69.969  1.00 42.75  ? 119  GLN C CB  1 
ATOM   8013  C CG  . GLN C 1 126 ? -17.439 -8.560  -70.298  1.00 42.89  ? 119  GLN C CG  1 
ATOM   8014  C CD  . GLN C 1 126 ? -18.095 -7.311  -69.779  1.00 43.01  ? 119  GLN C CD  1 
ATOM   8015  O OE1 . GLN C 1 126 ? -17.854 -6.854  -68.657  1.00 45.64  ? 119  GLN C OE1 1 
ATOM   8016  N NE2 . GLN C 1 126 ? -18.976 -6.780  -70.600  1.00 41.34  ? 119  GLN C NE2 1 
ATOM   8017  N N   . GLU C 1 127 ? -19.778 -12.822 -71.233  1.00 35.60  ? 120  GLU C N   1 
ATOM   8018  C CA  . GLU C 1 127 ? -20.228 -14.162 -70.793  1.00 36.94  ? 120  GLU C CA  1 
ATOM   8019  C C   . GLU C 1 127 ? -19.856 -15.184 -71.861  1.00 35.92  ? 120  GLU C C   1 
ATOM   8020  O O   . GLU C 1 127 ? -19.244 -16.181 -71.478  1.00 37.62  ? 120  GLU C O   1 
ATOM   8021  C CB  . GLU C 1 127 ? -21.727 -14.168 -70.500  1.00 41.27  ? 120  GLU C CB  1 
ATOM   8022  C CG  . GLU C 1 127 ? -22.212 -15.421 -69.790  1.00 39.92  ? 120  GLU C CG  1 
ATOM   8023  C CD  . GLU C 1 127 ? -21.815 -15.551 -68.334  1.00 40.25  ? 120  GLU C CD  1 
ATOM   8024  O OE1 . GLU C 1 127 ? -21.179 -14.602 -67.770  1.00 38.18  ? 120  GLU C OE1 1 
ATOM   8025  O OE2 . GLU C 1 127 ? -22.186 -16.602 -67.745  1.00 41.48  ? 120  GLU C OE2 1 
ATOM   8026  N N   . LEU C 1 128 ? -20.224 -14.949 -73.122  1.00 32.84  ? 121  LEU C N   1 
ATOM   8027  C CA  . LEU C 1 128 ? -19.845 -15.857 -74.230  1.00 36.15  ? 121  LEU C CA  1 
ATOM   8028  C C   . LEU C 1 128 ? -18.351 -15.687 -74.497  1.00 36.75  ? 121  LEU C C   1 
ATOM   8029  O O   . LEU C 1 128 ? -17.842 -14.557 -74.301  1.00 39.85  ? 121  LEU C O   1 
ATOM   8030  C CB  . LEU C 1 128 ? -20.664 -15.545 -75.488  1.00 36.70  ? 121  LEU C CB  1 
ATOM   8031  C CG  . LEU C 1 128 ? -21.997 -16.282 -75.592  1.00 36.97  ? 121  LEU C CG  1 
ATOM   8032  C CD1 . LEU C 1 128 ? -22.917 -15.888 -74.457  1.00 37.93  ? 121  LEU C CD1 1 
ATOM   8033  C CD2 . LEU C 1 128 ? -22.657 -16.027 -76.940  1.00 38.15  ? 121  LEU C CD2 1 
ATOM   8034  N N   . LEU C 1 129 ? -17.686 -16.773 -74.896  1.00 33.13  ? 122  LEU C N   1 
ATOM   8035  C CA  . LEU C 1 129 ? -16.236 -16.753 -75.198  1.00 29.61  ? 122  LEU C CA  1 
ATOM   8036  C C   . LEU C 1 129 ? -16.069 -15.786 -76.375  1.00 28.53  ? 122  LEU C C   1 
ATOM   8037  O O   . LEU C 1 129 ? -16.710 -16.017 -77.378  1.00 29.25  ? 122  LEU C O   1 
ATOM   8038  C CB  . LEU C 1 129 ? -15.744 -18.162 -75.550  1.00 28.77  ? 122  LEU C CB  1 
ATOM   8039  C CG  . LEU C 1 129 ? -16.094 -19.305 -74.593  1.00 27.40  ? 122  LEU C CG  1 
ATOM   8040  C CD1 . LEU C 1 129 ? -15.484 -20.616 -75.064  1.00 25.84  ? 122  LEU C CD1 1 
ATOM   8041  C CD2 . LEU C 1 129 ? -15.631 -19.017 -73.182  1.00 29.66  ? 122  LEU C CD2 1 
ATOM   8042  N N   . ASP C 1 130 ? -15.289 -14.711 -76.239  1.00 28.27  ? 123  ASP C N   1 
ATOM   8043  C CA  . ASP C 1 130 ? -15.049 -13.749 -77.345  1.00 26.61  ? 123  ASP C CA  1 
ATOM   8044  C C   . ASP C 1 130 ? -13.787 -14.188 -78.084  1.00 26.42  ? 123  ASP C C   1 
ATOM   8045  O O   . ASP C 1 130 ? -12.713 -14.287 -77.510  1.00 26.33  ? 123  ASP C O   1 
ATOM   8046  C CB  . ASP C 1 130 ? -15.023 -12.292 -76.879  1.00 26.77  ? 123  ASP C CB  1 
ATOM   8047  C CG  . ASP C 1 130 ? -14.174 -12.007 -75.659  1.00 29.71  ? 123  ASP C CG  1 
ATOM   8048  O OD1 . ASP C 1 130 ? -14.120 -12.868 -74.761  1.00 30.89  ? 123  ASP C OD1 1 
ATOM   8049  O OD2 . ASP C 1 130 ? -13.597 -10.908 -75.602  1.00 33.10  ? 123  ASP C OD2 1 
ATOM   8050  N N   . PRO C 1 131 ? -13.892 -14.468 -79.399  1.00 25.35  ? 124  PRO C N   1 
ATOM   8051  C CA  . PRO C 1 131 ? -12.842 -15.183 -80.119  1.00 24.14  ? 124  PRO C CA  1 
ATOM   8052  C C   . PRO C 1 131 ? -11.580 -14.367 -80.422  1.00 22.34  ? 124  PRO C C   1 
ATOM   8053  O O   . PRO C 1 131 ? -10.539 -14.965 -80.467  1.00 22.47  ? 124  PRO C O   1 
ATOM   8054  C CB  . PRO C 1 131 ? -13.552 -15.564 -81.413  1.00 26.24  ? 124  PRO C CB  1 
ATOM   8055  C CG  . PRO C 1 131 ? -14.548 -14.425 -81.639  1.00 26.16  ? 124  PRO C CG  1 
ATOM   8056  C CD  . PRO C 1 131 ? -15.032 -14.089 -80.252  1.00 25.90  ? 124  PRO C CD  1 
ATOM   8057  N N   . LEU C 1 132 ? -11.680 -13.047 -80.591  1.00 21.52  ? 125  LEU C N   1 
ATOM   8058  C CA  . LEU C 1 132 ? -10.485 -12.183 -80.817  1.00 22.38  ? 125  LEU C CA  1 
ATOM   8059  C C   . LEU C 1 132 ? -9.597  -12.154 -79.567  1.00 21.84  ? 125  LEU C C   1 
ATOM   8060  O O   . LEU C 1 132 ? -8.398  -12.022 -79.743  1.00 22.91  ? 125  LEU C O   1 
ATOM   8061  C CB  . LEU C 1 132 ? -10.911 -10.763 -81.191  1.00 22.95  ? 125  LEU C CB  1 
ATOM   8062  C CG  . LEU C 1 132 ? -11.712 -10.639 -82.480  1.00 23.51  ? 125  LEU C CG  1 
ATOM   8063  C CD1 . LEU C 1 132 ? -11.793 -9.186  -82.910  1.00 23.86  ? 125  LEU C CD1 1 
ATOM   8064  C CD2 . LEU C 1 132 ? -11.081 -11.479 -83.578  1.00 23.05  ? 125  LEU C CD2 1 
ATOM   8065  N N   . ARG C 1 133 ? -10.171 -12.229 -78.360  1.00 22.36  ? 126  ARG C N   1 
ATOM   8066  C CA  . ARG C 1 133 ? -9.412  -12.316 -77.083  1.00 21.79  ? 126  ARG C CA  1 
ATOM   8067  C C   . ARG C 1 133 ? -8.480  -13.520 -77.175  1.00 21.75  ? 126  ARG C C   1 
ATOM   8068  O O   . ARG C 1 133 ? -7.263  -13.332 -77.048  1.00 21.13  ? 126  ARG C O   1 
ATOM   8069  C CB  . ARG C 1 133 ? -10.349 -12.456 -75.879  1.00 21.92  ? 126  ARG C CB  1 
ATOM   8070  C CG  . ARG C 1 133 ? -9.647  -12.592 -74.532  1.00 21.79  ? 126  ARG C CG  1 
ATOM   8071  C CD  . ARG C 1 133 ? -10.611 -12.820 -73.370  1.00 21.27  ? 126  ARG C CD  1 
ATOM   8072  N NE  . ARG C 1 133 ? -11.665 -11.828 -73.406  1.00 20.65  ? 126  ARG C NE  1 
ATOM   8073  C CZ  . ARG C 1 133 ? -11.608 -10.619 -72.869  1.00 20.77  ? 126  ARG C CZ  1 
ATOM   8074  N NH1 . ARG C 1 133 ? -10.566 -10.217 -72.168  1.00 20.10  ? 126  ARG C NH1 1 
ATOM   8075  N NH2 . ARG C 1 133 ? -12.628 -9.808  -73.022  1.00 22.24  ? 126  ARG C NH2 1 
ATOM   8076  N N   . ALA C 1 134 ? -9.053  -14.694 -77.433  1.00 21.97  ? 127  ALA C N   1 
ATOM   8077  C CA  . ALA C 1 134 ? -8.348  -15.981 -77.595  1.00 23.30  ? 127  ALA C CA  1 
ATOM   8078  C C   . ALA C 1 134 ? -7.256  -15.856 -78.672  1.00 24.77  ? 127  ALA C C   1 
ATOM   8079  O O   . ALA C 1 134 ? -6.118  -16.327 -78.442  1.00 22.07  ? 127  ALA C O   1 
ATOM   8080  C CB  . ALA C 1 134 ? -9.363  -17.032 -77.957  1.00 24.00  ? 127  ALA C CB  1 
ATOM   8081  N N   . MET C 1 135 ? -7.587  -15.249 -79.811  1.00 25.35  ? 128  MET C N   1 
ATOM   8082  C CA  . MET C 1 135 ? -6.650  -15.092 -80.952  1.00 28.44  ? 128  MET C CA  1 
ATOM   8083  C C   . MET C 1 135 ? -5.508  -14.140 -80.578  1.00 25.39  ? 128  MET C C   1 
ATOM   8084  O O   . MET C 1 135 ? -4.340  -14.468 -80.884  1.00 24.25  ? 128  MET C O   1 
ATOM   8085  C CB  . MET C 1 135 ? -7.374  -14.583 -82.208  1.00 33.42  ? 128  MET C CB  1 
ATOM   8086  C CG  . MET C 1 135 ? -8.373  -15.594 -82.795  1.00 36.74  ? 128  MET C CG  1 
ATOM   8087  S SD  . MET C 1 135 ? -7.547  -17.076 -83.444  1.00 46.84  ? 128  MET C SD  1 
ATOM   8088  C CE  . MET C 1 135 ? -8.968  -18.000 -84.015  1.00 49.37  ? 128  MET C CE  1 
ATOM   8089  N N   . LEU C 1 136 ? -5.803  -13.007 -79.945  1.00 22.62  ? 129  LEU C N   1 
ATOM   8090  C CA  . LEU C 1 136 ? -4.747  -12.018 -79.609  1.00 21.26  ? 129  LEU C CA  1 
ATOM   8091  C C   . LEU C 1 136 ? -3.854  -12.613 -78.514  1.00 20.03  ? 129  LEU C C   1 
ATOM   8092  O O   . LEU C 1 136 ? -2.639  -12.363 -78.533  1.00 18.12  ? 129  LEU C O   1 
ATOM   8093  C CB  . LEU C 1 136 ? -5.378  -10.702 -79.158  1.00 21.92  ? 129  LEU C CB  1 
ATOM   8094  C CG  . LEU C 1 136 ? -4.380  -9.680  -78.620  1.00 22.89  ? 129  LEU C CG  1 
ATOM   8095  C CD1 . LEU C 1 136 ? -3.399  -9.266  -79.692  1.00 21.63  ? 129  LEU C CD1 1 
ATOM   8096  C CD2 . LEU C 1 136 ? -5.091  -8.465  -78.057  1.00 24.38  ? 129  LEU C CD2 1 
ATOM   8097  N N   . ALA C 1 137 ? -4.436  -13.375 -77.590  1.00 18.92  ? 130  ALA C N   1 
ATOM   8098  C CA  . ALA C 1 137 ? -3.688  -14.028 -76.499  1.00 20.07  ? 130  ALA C CA  1 
ATOM   8099  C C   . ALA C 1 137 ? -2.727  -15.050 -77.107  1.00 20.74  ? 130  ALA C C   1 
ATOM   8100  O O   . ALA C 1 137 ? -1.571  -15.086 -76.677  1.00 20.08  ? 130  ALA C O   1 
ATOM   8101  C CB  . ALA C 1 137 ? -4.620  -14.661 -75.495  1.00 20.65  ? 130  ALA C CB  1 
ATOM   8102  N N   . LYS C 1 138 ? -3.202  -15.859 -78.051  1.00 20.67  ? 131  LYS C N   1 
ATOM   8103  C CA  . LYS C 1 138 ? -2.375  -16.874 -78.751  1.00 22.25  ? 131  LYS C CA  1 
ATOM   8104  C C   . LYS C 1 138 ? -1.236  -16.151 -79.459  1.00 19.88  ? 131  LYS C C   1 
ATOM   8105  O O   . LYS C 1 138 ? -0.079  -16.579 -79.338  1.00 18.96  ? 131  LYS C O   1 
ATOM   8106  C CB  . LYS C 1 138 ? -3.244  -17.634 -79.759  1.00 27.68  ? 131  LYS C CB  1 
ATOM   8107  C CG  . LYS C 1 138 ? -2.509  -18.536 -80.747  1.00 31.15  ? 131  LYS C CG  1 
ATOM   8108  C CD  . LYS C 1 138 ? -1.762  -19.660 -80.085  1.00 37.07  ? 131  LYS C CD  1 
ATOM   8109  C CE  . LYS C 1 138 ? -1.426  -20.804 -81.018  1.00 39.98  ? 131  LYS C CE  1 
ATOM   8110  N NZ  . LYS C 1 138 ? -0.479  -21.717 -80.341  1.00 43.88  ? 131  LYS C NZ  1 
ATOM   8111  N N   . THR C 1 139 ? -1.582  -15.088 -80.174  1.00 18.60  ? 132  THR C N   1 
ATOM   8112  C CA  . THR C 1 139 ? -0.637  -14.240 -80.935  1.00 18.99  ? 132  THR C CA  1 
ATOM   8113  C C   . THR C 1 139 ? 0.421   -13.694 -79.978  1.00 18.42  ? 132  THR C C   1 
ATOM   8114  O O   . THR C 1 139 ? 1.609   -13.898 -80.241  1.00 18.45  ? 132  THR C O   1 
ATOM   8115  C CB  . THR C 1 139 ? -1.390  -13.156 -81.720  1.00 19.52  ? 132  THR C CB  1 
ATOM   8116  O OG1 . THR C 1 139 ? -2.335  -13.820 -82.564  1.00 20.17  ? 132  THR C OG1 1 
ATOM   8117  C CG2 . THR C 1 139 ? -0.479  -12.301 -82.576  1.00 19.44  ? 132  THR C CG2 1 
ATOM   8118  N N   . LEU C 1 140 ? 0.007   -13.061 -78.889  1.00 19.17  ? 133  LEU C N   1 
ATOM   8119  C CA  . LEU C 1 140 ? 0.947   -12.429 -77.936  1.00 19.24  ? 133  LEU C CA  1 
ATOM   8120  C C   . LEU C 1 140 ? 1.832   -13.503 -77.292  1.00 20.92  ? 133  LEU C C   1 
ATOM   8121  O O   . LEU C 1 140 ? 3.015   -13.201 -77.054  1.00 21.18  ? 133  LEU C O   1 
ATOM   8122  C CB  . LEU C 1 140 ? 0.181   -11.602 -76.899  1.00 19.43  ? 133  LEU C CB  1 
ATOM   8123  C CG  . LEU C 1 140 ? -0.228  -10.209 -77.377  1.00 19.76  ? 133  LEU C CG  1 
ATOM   8124  C CD1 . LEU C 1 140 ? -1.007  -9.467  -76.316  1.00 20.84  ? 133  LEU C CD1 1 
ATOM   8125  C CD2 . LEU C 1 140 ? 0.980   -9.389  -77.763  1.00 20.21  ? 133  LEU C CD2 1 
ATOM   8126  N N   . ALA C 1 141 ? 1.329   -14.718 -77.068  1.00 20.94  ? 134  ALA C N   1 
ATOM   8127  C CA  . ALA C 1 141 ? 2.124   -15.836 -76.504  1.00 21.89  ? 134  ALA C CA  1 
ATOM   8128  C C   . ALA C 1 141 ? 3.250   -16.208 -77.478  1.00 22.79  ? 134  ALA C C   1 
ATOM   8129  O O   . ALA C 1 141 ? 4.413   -16.334 -77.027  1.00 24.53  ? 134  ALA C O   1 
ATOM   8130  C CB  . ALA C 1 141 ? 1.231   -17.014 -76.213  1.00 21.55  ? 134  ALA C CB  1 
ATOM   8131  N N   . ALA C 1 142 ? 2.930   -16.357 -78.768  1.00 22.81  ? 135  ALA C N   1 
ATOM   8132  C CA  . ALA C 1 142 ? 3.907   -16.653 -79.843  1.00 21.80  ? 135  ALA C CA  1 
ATOM   8133  C C   . ALA C 1 142 ? 4.908   -15.497 -79.999  1.00 21.31  ? 135  ALA C C   1 
ATOM   8134  O O   . ALA C 1 142 ? 6.098   -15.762 -80.262  1.00 21.15  ? 135  ALA C O   1 
ATOM   8135  C CB  . ALA C 1 142 ? 3.173   -16.928 -81.138  1.00 22.36  ? 135  ALA C CB  1 
ATOM   8136  N N   . LEU C 1 143 ? 4.452   -14.256 -79.858  1.00 21.50  ? 136  LEU C N   1 
ATOM   8137  C CA  . LEU C 1 143 ? 5.288   -13.050 -80.089  1.00 23.62  ? 136  LEU C CA  1 
ATOM   8138  C C   . LEU C 1 143 ? 6.244   -12.837 -78.919  1.00 24.84  ? 136  LEU C C   1 
ATOM   8139  O O   . LEU C 1 143 ? 7.301   -12.258 -79.138  1.00 25.50  ? 136  LEU C O   1 
ATOM   8140  C CB  . LEU C 1 143 ? 4.378   -11.834 -80.251  1.00 25.74  ? 136  LEU C CB  1 
ATOM   8141  C CG  . LEU C 1 143 ? 5.085   -10.538 -80.648  1.00 27.19  ? 136  LEU C CG  1 
ATOM   8142  C CD1 . LEU C 1 143 ? 5.795   -10.691 -81.979  1.00 26.29  ? 136  LEU C CD1 1 
ATOM   8143  C CD2 . LEU C 1 143 ? 4.094   -9.380  -80.718  1.00 27.66  ? 136  LEU C CD2 1 
ATOM   8144  N N   . THR C 1 144 ? 5.865   -13.250 -77.708  1.00 26.41  ? 137  THR C N   1 
ATOM   8145  C CA  . THR C 1 144 ? 6.646   -12.955 -76.475  1.00 27.79  ? 137  THR C CA  1 
ATOM   8146  C C   . THR C 1 144 ? 7.691   -14.027 -76.213  1.00 30.40  ? 137  THR C C   1 
ATOM   8147  O O   . THR C 1 144 ? 7.522   -15.188 -76.585  1.00 32.77  ? 137  THR C O   1 
ATOM   8148  C CB  . THR C 1 144 ? 5.781   -12.836 -75.219  1.00 25.03  ? 137  THR C CB  1 
ATOM   8149  O OG1 . THR C 1 144 ? 4.963   -14.003 -75.136  1.00 24.41  ? 137  THR C OG1 1 
ATOM   8150  C CG2 . THR C 1 144 ? 4.983   -11.557 -75.201  1.00 24.24  ? 137  THR C CG2 1 
ATOM   8151  N N   . PRO C 1 145 ? 8.778   -13.639 -75.514  1.00 34.51  ? 138  PRO C N   1 
ATOM   8152  C CA  . PRO C 1 145 ? 9.860   -14.556 -75.180  1.00 36.97  ? 138  PRO C CA  1 
ATOM   8153  C C   . PRO C 1 145 ? 9.474   -15.628 -74.152  1.00 38.04  ? 138  PRO C C   1 
ATOM   8154  O O   . PRO C 1 145 ? 8.713   -15.347 -73.275  1.00 37.31  ? 138  PRO C O   1 
ATOM   8155  C CB  . PRO C 1 145 ? 10.963  -13.641 -74.609  1.00 35.58  ? 138  PRO C CB  1 
ATOM   8156  C CG  . PRO C 1 145 ? 10.244  -12.403 -74.130  1.00 34.72  ? 138  PRO C CG  1 
ATOM   8157  C CD  . PRO C 1 145 ? 9.053   -12.267 -75.050  1.00 35.39  ? 138  PRO C CD  1 
ATOM   8158  N N   . GLY C 1 146 ? 10.038  -16.825 -74.331  1.00 40.58  ? 139  GLY C N   1 
ATOM   8159  C CA  . GLY C 1 146 ? 10.148  -17.898 -73.321  1.00 38.73  ? 139  GLY C CA  1 
ATOM   8160  C C   . GLY C 1 146 ? 8.794   -18.330 -72.798  1.00 37.49  ? 139  GLY C C   1 
ATOM   8161  O O   . GLY C 1 146 ? 7.918   -18.673 -73.612  1.00 32.55  ? 139  GLY C O   1 
ATOM   8162  N N   . LYS C 1 147 ? 8.631   -18.252 -71.485  1.00 35.41  ? 140  LYS C N   1 
ATOM   8163  C CA  . LYS C 1 147 ? 7.538   -18.899 -70.730  1.00 36.46  ? 140  LYS C CA  1 
ATOM   8164  C C   . LYS C 1 147 ? 6.402   -17.888 -70.514  1.00 30.87  ? 140  LYS C C   1 
ATOM   8165  O O   . LYS C 1 147 ? 5.416   -18.271 -69.862  1.00 32.80  ? 140  LYS C O   1 
ATOM   8166  C CB  . LYS C 1 147 ? 8.072   -19.462 -69.402  1.00 44.50  ? 140  LYS C CB  1 
ATOM   8167  C CG  . LYS C 1 147 ? 9.445   -20.135 -69.389  1.00 53.33  ? 140  LYS C CG  1 
ATOM   8168  C CD  . LYS C 1 147 ? 9.423   -21.648 -69.211  1.00 59.31  ? 140  LYS C CD  1 
ATOM   8169  C CE  . LYS C 1 147 ? 9.128   -22.370 -70.513  1.00 67.34  ? 140  LYS C CE  1 
ATOM   8170  N NZ  . LYS C 1 147 ? 8.460   -23.674 -70.288  1.00 71.20  ? 140  LYS C NZ  1 
ATOM   8171  N N   . LEU C 1 148 ? 6.509   -16.660 -71.042  1.00 26.81  ? 141  LEU C N   1 
ATOM   8172  C CA  . LEU C 1 148 ? 5.369   -15.697 -71.129  1.00 24.99  ? 141  LEU C CA  1 
ATOM   8173  C C   . LEU C 1 148 ? 4.269   -16.333 -72.002  1.00 24.45  ? 141  LEU C C   1 
ATOM   8174  O O   . LEU C 1 148 ? 4.529   -16.558 -73.212  1.00 27.85  ? 141  LEU C O   1 
ATOM   8175  C CB  . LEU C 1 148 ? 5.857   -14.360 -71.716  1.00 22.23  ? 141  LEU C CB  1 
ATOM   8176  C CG  . LEU C 1 148 ? 6.072   -13.148 -70.791  1.00 21.23  ? 141  LEU C CG  1 
ATOM   8177  C CD1 . LEU C 1 148 ? 6.243   -13.541 -69.335  1.00 21.12  ? 141  LEU C CD1 1 
ATOM   8178  C CD2 . LEU C 1 148 ? 7.235   -12.290 -71.240  1.00 20.23  ? 141  LEU C CD2 1 
ATOM   8179  N N   . LYS C 1 149 ? 3.101   -16.605 -71.416  1.00 22.71  ? 142  LYS C N   1 
ATOM   8180  C CA  . LYS C 1 149 ? 2.083   -17.511 -72.007  1.00 22.51  ? 142  LYS C CA  1 
ATOM   8181  C C   . LYS C 1 149 ? 0.659   -16.979 -71.808  1.00 21.51  ? 142  LYS C C   1 
ATOM   8182  O O   . LYS C 1 149 ? -0.164  -17.212 -72.705  1.00 22.51  ? 142  LYS C O   1 
ATOM   8183  C CB  . LYS C 1 149 ? 2.214   -18.912 -71.399  1.00 23.81  ? 142  LYS C CB  1 
ATOM   8184  C CG  . LYS C 1 149 ? 1.310   -19.983 -72.000  1.00 24.02  ? 142  LYS C CG  1 
ATOM   8185  C CD  . LYS C 1 149 ? 1.774   -21.403 -71.703  1.00 24.94  ? 142  LYS C CD  1 
ATOM   8186  C CE  . LYS C 1 149 ? 0.900   -22.485 -72.305  1.00 25.29  ? 142  LYS C CE  1 
ATOM   8187  N NZ  . LYS C 1 149 ? -0.323  -22.716 -71.492  1.00 27.59  ? 142  LYS C NZ  1 
ATOM   8188  N N   . TYR C 1 150 ? 0.336   -16.349 -70.681  1.00 20.65  ? 143  TYR C N   1 
ATOM   8189  C CA  . TYR C 1 150 ? -1.056  -15.931 -70.385  1.00 20.42  ? 143  TYR C CA  1 
ATOM   8190  C C   . TYR C 1 150 ? -1.128  -14.421 -70.445  1.00 19.70  ? 143  TYR C C   1 
ATOM   8191  O O   . TYR C 1 150 ? -0.185  -13.755 -70.044  1.00 17.07  ? 143  TYR C O   1 
ATOM   8192  C CB  . TYR C 1 150 ? -1.557  -16.492 -69.059  1.00 21.43  ? 143  TYR C CB  1 
ATOM   8193  C CG  . TYR C 1 150 ? -1.961  -17.939 -69.167  1.00 22.35  ? 143  TYR C CG  1 
ATOM   8194  C CD1 . TYR C 1 150 ? -1.023  -18.949 -68.998  1.00 23.14  ? 143  TYR C CD1 1 
ATOM   8195  C CD2 . TYR C 1 150 ? -3.252  -18.308 -69.496  1.00 23.04  ? 143  TYR C CD2 1 
ATOM   8196  C CE1 . TYR C 1 150 ? -1.364  -20.288 -69.103  1.00 22.79  ? 143  TYR C CE1 1 
ATOM   8197  C CE2 . TYR C 1 150 ? -3.607  -19.645 -69.613  1.00 23.96  ? 143  TYR C CE2 1 
ATOM   8198  C CZ  . TYR C 1 150 ? -2.661  -20.640 -69.411  1.00 23.86  ? 143  TYR C CZ  1 
ATOM   8199  O OH  . TYR C 1 150 ? -2.985  -21.962 -69.530  1.00 25.37  ? 143  TYR C OH  1 
ATOM   8200  N N   . SER C 1 151 ? -2.227  -13.949 -71.023  1.00 21.56  ? 144  SER C N   1 
ATOM   8201  C CA  . SER C 1 151 ? -2.510  -12.519 -71.282  1.00 22.42  ? 144  SER C CA  1 
ATOM   8202  C C   . SER C 1 151 ? -3.828  -12.139 -70.604  1.00 22.00  ? 144  SER C C   1 
ATOM   8203  O O   . SER C 1 151 ? -4.813  -12.916 -70.682  1.00 22.36  ? 144  SER C O   1 
ATOM   8204  C CB  . SER C 1 151 ? -2.524  -12.229 -72.754  1.00 21.87  ? 144  SER C CB  1 
ATOM   8205  O OG  . SER C 1 151 ? -1.270  -12.572 -73.313  1.00 21.93  ? 144  SER C OG  1 
ATOM   8206  N N   . PHE C 1 152 ? -3.787  -10.996 -69.928  1.00 20.89  ? 145  PHE C N   1 
ATOM   8207  C CA  . PHE C 1 152 ? -4.949  -10.276 -69.380  1.00 21.11  ? 145  PHE C CA  1 
ATOM   8208  C C   . PHE C 1 152 ? -5.016  -8.916  -70.063  1.00 20.89  ? 145  PHE C C   1 
ATOM   8209  O O   . PHE C 1 152 ? -4.014  -8.207  -70.041  1.00 22.10  ? 145  PHE C O   1 
ATOM   8210  C CB  . PHE C 1 152 ? -4.814  -10.102 -67.871  1.00 22.48  ? 145  PHE C CB  1 
ATOM   8211  C CG  . PHE C 1 152 ? -5.861  -9.190  -67.310  1.00 22.50  ? 145  PHE C CG  1 
ATOM   8212  C CD1 . PHE C 1 152 ? -7.106  -9.691  -66.982  1.00 22.23  ? 145  PHE C CD1 1 
ATOM   8213  C CD2 . PHE C 1 152 ? -5.626  -7.828  -67.202  1.00 23.03  ? 145  PHE C CD2 1 
ATOM   8214  C CE1 . PHE C 1 152 ? -8.104  -8.841  -66.542  1.00 23.20  ? 145  PHE C CE1 1 
ATOM   8215  C CE2 . PHE C 1 152 ? -6.614  -6.981  -66.732  1.00 23.22  ? 145  PHE C CE2 1 
ATOM   8216  C CZ  . PHE C 1 152 ? -7.854  -7.491  -66.421  1.00 23.41  ? 145  PHE C CZ  1 
ATOM   8217  N N   . PHE C 1 153 ? -6.165  -8.592  -70.654  1.00 21.10  ? 146  PHE C N   1 
ATOM   8218  C CA  . PHE C 1 153 ? -6.387  -7.364  -71.452  1.00 20.57  ? 146  PHE C CA  1 
ATOM   8219  C C   . PHE C 1 153 ? -7.166  -6.338  -70.636  1.00 19.43  ? 146  PHE C C   1 
ATOM   8220  O O   . PHE C 1 153 ? -8.141  -6.674  -69.964  1.00 18.58  ? 146  PHE C O   1 
ATOM   8221  C CB  . PHE C 1 153 ? -7.089  -7.723  -72.753  1.00 21.51  ? 146  PHE C CB  1 
ATOM   8222  C CG  . PHE C 1 153 ? -6.301  -8.717  -73.568  1.00 23.43  ? 146  PHE C CG  1 
ATOM   8223  C CD1 . PHE C 1 153 ? -5.072  -8.371  -74.095  1.00 21.86  ? 146  PHE C CD1 1 
ATOM   8224  C CD2 . PHE C 1 153 ? -6.753  -10.016 -73.753  1.00 24.26  ? 146  PHE C CD2 1 
ATOM   8225  C CE1 . PHE C 1 153 ? -4.338  -9.288  -74.824  1.00 23.59  ? 146  PHE C CE1 1 
ATOM   8226  C CE2 . PHE C 1 153 ? -6.020  -10.927 -74.493  1.00 23.25  ? 146  PHE C CE2 1 
ATOM   8227  C CZ  . PHE C 1 153 ? -4.817  -10.558 -75.032  1.00 23.43  ? 146  PHE C CZ  1 
ATOM   8228  N N   . CYS C 1 154 ? -6.694  -5.105  -70.698  1.00 18.90  ? 147  CYS C N   1 
ATOM   8229  C CA  . CYS C 1 154 ? -7.269  -3.922  -70.031  1.00 17.74  ? 147  CYS C CA  1 
ATOM   8230  C C   . CYS C 1 154 ? -7.263  -2.790  -71.065  1.00 16.44  ? 147  CYS C C   1 
ATOM   8231  O O   . CYS C 1 154 ? -7.123  -3.097  -72.274  1.00 15.35  ? 147  CYS C O   1 
ATOM   8232  C CB  . CYS C 1 154 ? -6.475  -3.609  -68.772  1.00 18.84  ? 147  CYS C CB  1 
ATOM   8233  S SG  . CYS C 1 154 ? -4.674  -3.657  -69.024  1.00 22.14  ? 147  CYS C SG  1 
ATOM   8234  N N   . ASN C 1 155 ? -7.383  -1.544  -70.621  1.00 15.73  ? 148  ASN C N   1 
ATOM   8235  C CA  . ASN C 1 155 ? -7.673  -0.395  -71.503  1.00 15.96  ? 148  ASN C CA  1 
ATOM   8236  C C   . ASN C 1 155 ? -6.563  0.654   -71.468  1.00 15.95  ? 148  ASN C C   1 
ATOM   8237  O O   . ASN C 1 155 ? -6.729  1.643   -72.206  1.00 15.89  ? 148  ASN C O   1 
ATOM   8238  C CB  . ASN C 1 155 ? -9.016  0.233   -71.131  1.00 17.28  ? 148  ASN C CB  1 
ATOM   8239  C CG  . ASN C 1 155 ? -10.145 -0.773  -71.067  1.00 17.92  ? 148  ASN C CG  1 
ATOM   8240  O OD1 . ASN C 1 155 ? -10.527 -1.326  -72.090  1.00 20.12  ? 148  ASN C OD1 1 
ATOM   8241  N ND2 . ASN C 1 155 ? -10.682 -1.003  -69.880  1.00 18.32  ? 148  ASN C ND2 1 
ATOM   8242  N N   . SER C 1 156 ? -5.492  0.488   -70.677  1.00 14.91  ? 149  SER C N   1 
ATOM   8243  C CA  . SER C 1 156 ? -4.434  1.527   -70.572  1.00 14.80  ? 149  SER C CA  1 
ATOM   8244  C C   . SER C 1 156 ? -3.131  0.967   -69.971  1.00 15.12  ? 149  SER C C   1 
ATOM   8245  O O   . SER C 1 156 ? -3.141  -0.171  -69.442  1.00 15.50  ? 149  SER C O   1 
ATOM   8246  C CB  . SER C 1 156 ? -4.935  2.678   -69.741  1.00 15.60  ? 149  SER C CB  1 
ATOM   8247  O OG  . SER C 1 156 ? -5.214  2.251   -68.407  1.00 12.96  ? 149  SER C OG  1 
ATOM   8248  N N   . GLY C 1 157 ? -2.046  1.738   -70.056  1.00 14.72  ? 150  GLY C N   1 
ATOM   8249  C CA  . GLY C 1 157 ? -0.770  1.373   -69.429  1.00 15.31  ? 150  GLY C CA  1 
ATOM   8250  C C   . GLY C 1 157 ? -0.949  1.203   -67.934  1.00 16.03  ? 150  GLY C C   1 
ATOM   8251  O O   . GLY C 1 157 ? -0.564  0.154   -67.374  1.00 16.91  ? 150  GLY C O   1 
ATOM   8252  N N   . THR C 1 158 ? -1.566  2.185   -67.289  1.00 16.23  ? 151  THR C N   1 
ATOM   8253  C CA  . THR C 1 158 ? -1.743  2.192   -65.823  1.00 16.59  ? 151  THR C CA  1 
ATOM   8254  C C   . THR C 1 158 ? -2.550  0.957   -65.410  1.00 17.17  ? 151  THR C C   1 
ATOM   8255  O O   . THR C 1 158 ? -2.177  0.344   -64.409  1.00 18.44  ? 151  THR C O   1 
ATOM   8256  C CB  . THR C 1 158 ? -2.307  3.538   -65.358  1.00 17.25  ? 151  THR C CB  1 
ATOM   8257  O OG1 . THR C 1 158 ? -2.095  3.614   -63.952  1.00 17.62  ? 151  THR C OG1 1 
ATOM   8258  C CG2 . THR C 1 158 ? -3.772  3.723   -65.672  1.00 17.54  ? 151  THR C CG2 1 
ATOM   8259  N N   . GLU C 1 159 ? -3.555  0.548   -66.179  1.00 16.87  ? 152  GLU C N   1 
ATOM   8260  C CA  . GLU C 1 159 ? -4.357  -0.660  -65.860  1.00 17.83  ? 152  GLU C CA  1 
ATOM   8261  C C   . GLU C 1 159 ? -3.480  -1.902  -66.011  1.00 16.77  ? 152  GLU C C   1 
ATOM   8262  O O   . GLU C 1 159 ? -3.609  -2.809  -65.203  1.00 15.73  ? 152  GLU C O   1 
ATOM   8263  C CB  . GLU C 1 159 ? -5.615  -0.791  -66.728  1.00 20.26  ? 152  GLU C CB  1 
ATOM   8264  C CG  . GLU C 1 159 ? -6.827  -0.016  -66.215  1.00 22.31  ? 152  GLU C CG  1 
ATOM   8265  C CD  . GLU C 1 159 ? -8.148  -0.249  -66.974  1.00 24.42  ? 152  GLU C CD  1 
ATOM   8266  O OE1 . GLU C 1 159 ? -8.112  -0.406  -68.180  1.00 24.46  ? 152  GLU C OE1 1 
ATOM   8267  O OE2 . GLU C 1 159 ? -9.227  -0.264  -66.341  1.00 28.54  ? 152  GLU C OE2 1 
ATOM   8268  N N   A SER C 1 160 ? -2.616  -1.944  -67.028  0.50 17.65  ? 153  SER C N   1 
ATOM   8269  N N   B SER C 1 160 ? -2.620  -1.945  -67.028  0.50 17.54  ? 153  SER C N   1 
ATOM   8270  C CA  A SER C 1 160 ? -1.714  -3.101  -67.291  0.50 18.05  ? 153  SER C CA  1 
ATOM   8271  C CA  B SER C 1 160 ? -1.717  -3.099  -67.294  0.50 17.87  ? 153  SER C CA  1 
ATOM   8272  C C   A SER C 1 160 ? -0.738  -3.251  -66.126  0.50 17.64  ? 153  SER C C   1 
ATOM   8273  C C   B SER C 1 160 ? -0.742  -3.252  -66.127  0.50 17.54  ? 153  SER C C   1 
ATOM   8274  O O   A SER C 1 160 ? -0.446  -4.394  -65.755  0.50 17.42  ? 153  SER C O   1 
ATOM   8275  O O   B SER C 1 160 ? -0.457  -4.400  -65.750  0.50 17.32  ? 153  SER C O   1 
ATOM   8276  C CB  A SER C 1 160 ? -0.979  -2.991  -68.610  0.50 18.20  ? 153  SER C CB  1 
ATOM   8277  C CB  B SER C 1 160 ? -0.991  -2.980  -68.619  0.50 17.91  ? 153  SER C CB  1 
ATOM   8278  O OG  A SER C 1 160 ? -0.006  -4.022  -68.711  0.50 18.19  ? 153  SER C OG  1 
ATOM   8279  O OG  B SER C 1 160 ? -0.168  -1.823  -68.669  0.50 17.65  ? 153  SER C OG  1 
ATOM   8280  N N   . VAL C 1 161 ? -0.286  -2.132  -65.563  1.00 18.02  ? 154  VAL C N   1 
ATOM   8281  C CA  . VAL C 1 161 ? 0.645   -2.119  -64.394  1.00 18.65  ? 154  VAL C CA  1 
ATOM   8282  C C   . VAL C 1 161 ? -0.140  -2.576  -63.149  1.00 18.27  ? 154  VAL C C   1 
ATOM   8283  O O   . VAL C 1 161 ? 0.392   -3.419  -62.389  1.00 16.18  ? 154  VAL C O   1 
ATOM   8284  C CB  . VAL C 1 161 ? 1.311   -0.735  -64.237  1.00 18.35  ? 154  VAL C CB  1 
ATOM   8285  C CG1 . VAL C 1 161 ? 1.880   -0.518  -62.844  1.00 18.01  ? 154  VAL C CG1 1 
ATOM   8286  C CG2 . VAL C 1 161 ? 2.355   -0.497  -65.318  1.00 18.10  ? 154  VAL C CG2 1 
ATOM   8287  N N   . GLU C 1 162 ? -1.378  -2.097  -62.964  1.00 18.43  ? 155  GLU C N   1 
ATOM   8288  C CA  . GLU C 1 162 ? -2.227  -2.514  -61.812  1.00 18.54  ? 155  GLU C CA  1 
ATOM   8289  C C   . GLU C 1 162 ? -2.351  -4.033  -61.842  1.00 16.87  ? 155  GLU C C   1 
ATOM   8290  O O   . GLU C 1 162 ? -2.138  -4.661  -60.807  1.00 15.83  ? 155  GLU C O   1 
ATOM   8291  C CB  . GLU C 1 162 ? -3.613  -1.894  -61.871  1.00 20.98  ? 155  GLU C CB  1 
ATOM   8292  C CG  . GLU C 1 162 ? -3.605  -0.393  -61.689  1.00 23.75  ? 155  GLU C CG  1 
ATOM   8293  C CD  . GLU C 1 162 ? -3.548  0.103   -60.260  1.00 26.75  ? 155  GLU C CD  1 
ATOM   8294  O OE1 . GLU C 1 162 ? -3.826  -0.693  -59.340  1.00 32.03  ? 155  GLU C OE1 1 
ATOM   8295  O OE2 . GLU C 1 162 ? -3.254  1.304   -60.071  1.00 30.45  ? 155  GLU C OE2 1 
ATOM   8296  N N   . ALA C 1 163 ? -2.637  -4.591  -63.015  1.00 16.14  ? 156  ALA C N   1 
ATOM   8297  C CA  . ALA C 1 163 ? -2.806  -6.047  -63.222  1.00 15.73  ? 156  ALA C CA  1 
ATOM   8298  C C   . ALA C 1 163 ? -1.514  -6.775  -62.843  1.00 14.79  ? 156  ALA C C   1 
ATOM   8299  O O   . ALA C 1 163 ? -1.588  -7.823  -62.191  1.00 14.25  ? 156  ALA C O   1 
ATOM   8300  C CB  . ALA C 1 163 ? -3.204  -6.326  -64.651  1.00 16.20  ? 156  ALA C CB  1 
ATOM   8301  N N   . ALA C 1 164 ? -0.368  -6.228  -63.223  1.00 14.37  ? 157  ALA C N   1 
ATOM   8302  C CA  . ALA C 1 164 ? 0.953   -6.817  -62.926  1.00 14.40  ? 157  ALA C CA  1 
ATOM   8303  C C   . ALA C 1 164 ? 1.163   -6.847  -61.411  1.00 13.94  ? 157  ALA C C   1 
ATOM   8304  O O   . ALA C 1 164 ? 1.422   -7.931  -60.844  1.00 13.19  ? 157  ALA C O   1 
ATOM   8305  C CB  . ALA C 1 164 ? 2.023   -6.011  -63.628  1.00 14.90  ? 157  ALA C CB  1 
ATOM   8306  N N   . LEU C 1 165 ? 1.054   -5.679  -60.780  1.00 14.00  ? 158  LEU C N   1 
ATOM   8307  C CA  . LEU C 1 165 ? 1.193   -5.531  -59.312  1.00 13.94  ? 158  LEU C CA  1 
ATOM   8308  C C   . LEU C 1 165 ? 0.253   -6.550  -58.659  1.00 14.00  ? 158  LEU C C   1 
ATOM   8309  O O   . LEU C 1 165 ? 0.684   -7.199  -57.709  1.00 13.35  ? 158  LEU C O   1 
ATOM   8310  C CB  . LEU C 1 165 ? 0.822   -4.102  -58.893  1.00 14.47  ? 158  LEU C CB  1 
ATOM   8311  C CG  . LEU C 1 165 ? 1.756   -2.990  -59.371  1.00 14.14  ? 158  LEU C CG  1 
ATOM   8312  C CD1 . LEU C 1 165 ? 1.220   -1.600  -59.029  1.00 14.37  ? 158  LEU C CD1 1 
ATOM   8313  C CD2 . LEU C 1 165 ? 3.127   -3.167  -58.784  1.00 14.25  ? 158  LEU C CD2 1 
ATOM   8314  N N   . LYS C 1 166 ? -0.960  -6.720  -59.193  1.00 13.26  ? 159  LYS C N   1 
ATOM   8315  C CA  . LYS C 1 166 ? -1.960  -7.623  -58.596  1.00 13.68  ? 159  LYS C CA  1 
ATOM   8316  C C   . LYS C 1 166 ? -1.523  -9.074  -58.794  1.00 13.67  ? 159  LYS C C   1 
ATOM   8317  O O   . LYS C 1 166 ? -1.578  -9.836  -57.822  1.00 13.74  ? 159  LYS C O   1 
ATOM   8318  C CB  . LYS C 1 166 ? -3.356  -7.310  -59.136  1.00 14.72  ? 159  LYS C CB  1 
ATOM   8319  C CG  . LYS C 1 166 ? -4.017  -6.094  -58.492  1.00 15.35  ? 159  LYS C CG  1 
ATOM   8320  C CD  . LYS C 1 166 ? -5.471  -5.860  -58.878  1.00 15.91  ? 159  LYS C CD  1 
ATOM   8321  C CE  . LYS C 1 166 ? -6.430  -6.862  -58.266  1.00 16.74  ? 159  LYS C CE  1 
ATOM   8322  N NZ  . LYS C 1 166 ? -7.847  -6.690  -58.707  1.00 16.73  ? 159  LYS C NZ  1 
ATOM   8323  N N   . LEU C 1 167 ? -1.057  -9.457  -59.978  1.00 14.64  ? 160  LEU C N   1 
ATOM   8324  C CA  . LEU C 1 167 ? -0.534  -10.834 -60.200  1.00 15.60  ? 160  LEU C CA  1 
ATOM   8325  C C   . LEU C 1 167 ? 0.561   -11.114 -59.166  1.00 15.52  ? 160  LEU C C   1 
ATOM   8326  O O   . LEU C 1 167 ? 0.515   -12.159 -58.483  1.00 15.30  ? 160  LEU C O   1 
ATOM   8327  C CB  . LEU C 1 167 ? -0.013  -10.973 -61.630  1.00 17.02  ? 160  LEU C CB  1 
ATOM   8328  C CG  . LEU C 1 167 ? -1.095  -11.049 -62.704  1.00 17.51  ? 160  LEU C CG  1 
ATOM   8329  C CD1 . LEU C 1 167 ? -0.476  -10.953 -64.072  1.00 19.17  ? 160  LEU C CD1 1 
ATOM   8330  C CD2 . LEU C 1 167 ? -1.888  -12.333 -62.597  1.00 17.88  ? 160  LEU C CD2 1 
ATOM   8331  N N   . ALA C 1 168 ? 1.468   -10.167 -58.984  1.00 16.02  ? 161  ALA C N   1 
ATOM   8332  C CA  . ALA C 1 168 ? 2.608   -10.325 -58.058  1.00 16.82  ? 161  ALA C CA  1 
ATOM   8333  C C   . ALA C 1 168 ? 2.084   -10.498 -56.625  1.00 16.86  ? 161  ALA C C   1 
ATOM   8334  O O   . ALA C 1 168 ? 2.532   -11.418 -55.900  1.00 16.84  ? 161  ALA C O   1 
ATOM   8335  C CB  . ALA C 1 168 ? 3.538   -9.138  -58.200  1.00 17.38  ? 161  ALA C CB  1 
ATOM   8336  N N   . LYS C 1 169 ? 1.164   -9.632  -56.231  1.00 17.30  ? 162  LYS C N   1 
ATOM   8337  C CA  . LYS C 1 169 ? 0.583   -9.631  -54.864  1.00 17.57  ? 162  LYS C CA  1 
ATOM   8338  C C   . LYS C 1 169 ? -0.046  -11.000 -54.606  1.00 17.61  ? 162  LYS C C   1 
ATOM   8339  O O   . LYS C 1 169 ? 0.205   -11.560 -53.550  1.00 20.52  ? 162  LYS C O   1 
ATOM   8340  C CB  . LYS C 1 169 ? -0.409  -8.476  -54.691  1.00 17.11  ? 162  LYS C CB  1 
ATOM   8341  C CG  . LYS C 1 169 ? 0.228   -7.101  -54.505  1.00 17.23  ? 162  LYS C CG  1 
ATOM   8342  C CD  . LYS C 1 169 ? -0.770  -5.981  -54.300  1.00 16.79  ? 162  LYS C CD  1 
ATOM   8343  C CE  . LYS C 1 169 ? -0.206  -4.748  -53.629  1.00 16.53  ? 162  LYS C CE  1 
ATOM   8344  N NZ  . LYS C 1 169 ? -0.218  -4.859  -52.150  1.00 15.49  ? 162  LYS C NZ  1 
ATOM   8345  N N   . ALA C 1 170 ? -0.808  -11.530 -55.553  1.00 18.14  ? 163  ALA C N   1 
ATOM   8346  C CA  . ALA C 1 170 ? -1.559  -12.793 -55.380  1.00 18.61  ? 163  ALA C CA  1 
ATOM   8347  C C   . ALA C 1 170 ? -0.566  -13.959 -55.320  1.00 18.75  ? 163  ALA C C   1 
ATOM   8348  O O   . ALA C 1 170 ? -0.807  -14.934 -54.586  1.00 20.09  ? 163  ALA C O   1 
ATOM   8349  C CB  . ALA C 1 170 ? -2.565  -12.958 -56.489  1.00 18.85  ? 163  ALA C CB  1 
ATOM   8350  N N   . TYR C 1 171 ? 0.518   -13.874 -56.074  1.00 19.05  ? 164  TYR C N   1 
ATOM   8351  C CA  . TYR C 1 171 ? 1.540   -14.944 -56.102  1.00 20.10  ? 164  TYR C CA  1 
ATOM   8352  C C   . TYR C 1 171 ? 2.309   -14.949 -54.786  1.00 19.93  ? 164  TYR C C   1 
ATOM   8353  O O   . TYR C 1 171 ? 2.559   -16.034 -54.246  1.00 20.51  ? 164  TYR C O   1 
ATOM   8354  C CB  . TYR C 1 171 ? 2.505   -14.761 -57.269  1.00 19.74  ? 164  TYR C CB  1 
ATOM   8355  C CG  . TYR C 1 171 ? 3.405   -15.949 -57.468  1.00 20.37  ? 164  TYR C CG  1 
ATOM   8356  C CD1 . TYR C 1 171 ? 2.921   -17.108 -58.053  1.00 21.00  ? 164  TYR C CD1 1 
ATOM   8357  C CD2 . TYR C 1 171 ? 4.732   -15.929 -57.048  1.00 21.37  ? 164  TYR C CD2 1 
ATOM   8358  C CE1 . TYR C 1 171 ? 3.741   -18.206 -58.256  1.00 22.45  ? 164  TYR C CE1 1 
ATOM   8359  C CE2 . TYR C 1 171 ? 5.564   -17.023 -57.236  1.00 21.36  ? 164  TYR C CE2 1 
ATOM   8360  C CZ  . TYR C 1 171 ? 5.068   -18.165 -57.847  1.00 22.57  ? 164  TYR C CZ  1 
ATOM   8361  O OH  . TYR C 1 171 ? 5.859   -19.262 -58.047  1.00 23.83  ? 164  TYR C OH  1 
ATOM   8362  N N   . GLN C 1 172 ? 2.645   -13.762 -54.279  1.00 21.28  ? 165  GLN C N   1 
ATOM   8363  C CA  . GLN C 1 172 ? 3.721   -13.577 -53.267  1.00 21.50  ? 165  GLN C CA  1 
ATOM   8364  C C   . GLN C 1 172 ? 3.174   -13.455 -51.834  1.00 23.52  ? 165  GLN C C   1 
ATOM   8365  O O   . GLN C 1 172 ? 3.932   -13.796 -50.899  1.00 25.01  ? 165  GLN C O   1 
ATOM   8366  C CB  . GLN C 1 172 ? 4.578   -12.367 -53.646  1.00 20.64  ? 165  GLN C CB  1 
ATOM   8367  C CG  . GLN C 1 172 ? 5.450   -12.593 -54.877  1.00 21.02  ? 165  GLN C CG  1 
ATOM   8368  C CD  . GLN C 1 172 ? 6.613   -13.531 -54.645  1.00 19.94  ? 165  GLN C CD  1 
ATOM   8369  O OE1 . GLN C 1 172 ? 6.454   -14.679 -54.261  1.00 20.46  ? 165  GLN C OE1 1 
ATOM   8370  N NE2 . GLN C 1 172 ? 7.804   -13.063 -54.942  1.00 19.05  ? 165  GLN C NE2 1 
ATOM   8371  N N   . SER C 1 173 ? 1.938   -12.990 -51.623  1.00 26.10  ? 166  SER C N   1 
ATOM   8372  C CA  . SER C 1 173 ? 1.359   -12.817 -50.259  1.00 26.47  ? 166  SER C CA  1 
ATOM   8373  C C   . SER C 1 173 ? 1.247   -14.169 -49.549  1.00 24.17  ? 166  SER C C   1 
ATOM   8374  O O   . SER C 1 173 ? 1.688   -14.283 -48.411  1.00 23.37  ? 166  SER C O   1 
ATOM   8375  C CB  . SER C 1 173 ? 0.069   -12.043 -50.272  1.00 29.34  ? 166  SER C CB  1 
ATOM   8376  O OG  . SER C 1 173 ? -1.043  -12.868 -50.593  1.00 35.01  ? 166  SER C OG  1 
ATOM   8377  N N   . PRO C 1 174 ? 0.823   -15.264 -50.219  1.00 23.77  ? 167  PRO C N   1 
ATOM   8378  C CA  . PRO C 1 174 ? 0.844   -16.589 -49.611  1.00 25.15  ? 167  PRO C CA  1 
ATOM   8379  C C   . PRO C 1 174 ? 2.275   -17.079 -49.362  1.00 29.46  ? 167  PRO C C   1 
ATOM   8380  O O   . PRO C 1 174 ? 2.434   -18.018 -48.609  1.00 33.52  ? 167  PRO C O   1 
ATOM   8381  C CB  . PRO C 1 174 ? 0.233   -17.548 -50.635  1.00 25.28  ? 167  PRO C CB  1 
ATOM   8382  C CG  . PRO C 1 174 ? -0.261  -16.668 -51.784  1.00 25.85  ? 167  PRO C CG  1 
ATOM   8383  C CD  . PRO C 1 174 ? 0.417   -15.325 -51.633  1.00 25.44  ? 167  PRO C CD  1 
ATOM   8384  N N   . ARG C 1 175 ? 3.267   -16.473 -50.025  1.00 30.41  ? 168  ARG C N   1 
ATOM   8385  C CA  . ARG C 1 175 ? 4.709   -16.753 -49.789  1.00 29.68  ? 168  ARG C CA  1 
ATOM   8386  C C   . ARG C 1 175 ? 5.275   -15.758 -48.770  1.00 28.21  ? 168  ARG C C   1 
ATOM   8387  O O   . ARG C 1 175 ? 6.480   -15.830 -48.519  1.00 30.68  ? 168  ARG C O   1 
ATOM   8388  C CB  . ARG C 1 175 ? 5.461   -16.745 -51.122  1.00 29.55  ? 168  ARG C CB  1 
ATOM   8389  C CG  . ARG C 1 175 ? 5.020   -17.879 -52.035  1.00 31.70  ? 168  ARG C CG  1 
ATOM   8390  C CD  . ARG C 1 175 ? 5.551   -17.775 -53.448  1.00 32.01  ? 168  ARG C CD  1 
ATOM   8391  N NE  . ARG C 1 175 ? 5.379   -19.020 -54.179  1.00 30.62  ? 168  ARG C NE  1 
ATOM   8392  C CZ  . ARG C 1 175 ? 4.248   -19.407 -54.754  1.00 32.08  ? 168  ARG C CZ  1 
ATOM   8393  N NH1 . ARG C 1 175 ? 3.167   -18.639 -54.704  1.00 32.35  ? 168  ARG C NH1 1 
ATOM   8394  N NH2 . ARG C 1 175 ? 4.205   -20.564 -55.397  1.00 32.92  ? 168  ARG C NH2 1 
ATOM   8395  N N   . GLY C 1 176 ? 4.446   -14.874 -48.203  1.00 25.32  ? 169  GLY C N   1 
ATOM   8396  C CA  . GLY C 1 176 ? 4.858   -13.954 -47.128  1.00 22.97  ? 169  GLY C CA  1 
ATOM   8397  C C   . GLY C 1 176 ? 5.656   -12.757 -47.620  1.00 21.49  ? 169  GLY C C   1 
ATOM   8398  O O   . GLY C 1 176 ? 6.331   -12.154 -46.787  1.00 21.16  ? 169  GLY C O   1 
ATOM   8399  N N   . LYS C 1 177 ? 5.550   -12.374 -48.900  1.00 20.26  ? 170  LYS C N   1 
ATOM   8400  C CA  . LYS C 1 177 ? 6.299   -11.219 -49.453  1.00 19.71  ? 170  LYS C CA  1 
ATOM   8401  C C   . LYS C 1 177 ? 5.333   -10.143 -49.938  1.00 18.41  ? 170  LYS C C   1 
ATOM   8402  O O   . LYS C 1 177 ? 4.354   -10.481 -50.653  1.00 16.19  ? 170  LYS C O   1 
ATOM   8403  C CB  . LYS C 1 177 ? 7.216   -11.686 -50.576  1.00 22.36  ? 170  LYS C CB  1 
ATOM   8404  C CG  . LYS C 1 177 ? 8.259   -12.718 -50.167  1.00 24.65  ? 170  LYS C CG  1 
ATOM   8405  C CD  . LYS C 1 177 ? 9.066   -13.232 -51.348  1.00 26.54  ? 170  LYS C CD  1 
ATOM   8406  C CE  . LYS C 1 177 ? 10.123  -14.213 -50.912  1.00 29.08  ? 170  LYS C CE  1 
ATOM   8407  N NZ  . LYS C 1 177 ? 10.964  -14.625 -52.055  1.00 32.54  ? 170  LYS C NZ  1 
ATOM   8408  N N   . PHE C 1 178 ? 5.604   -8.897  -49.549  1.00 18.39  ? 171  PHE C N   1 
ATOM   8409  C CA  . PHE C 1 178 ? 4.658   -7.762  -49.726  1.00 20.00  ? 171  PHE C CA  1 
ATOM   8410  C C   . PHE C 1 178 ? 5.369   -6.501  -50.218  1.00 19.90  ? 171  PHE C C   1 
ATOM   8411  O O   . PHE C 1 178 ? 4.661   -5.584  -50.702  1.00 22.25  ? 171  PHE C O   1 
ATOM   8412  C CB  . PHE C 1 178 ? 3.908   -7.462  -48.419  1.00 20.45  ? 171  PHE C CB  1 
ATOM   8413  C CG  . PHE C 1 178 ? 3.156   -8.645  -47.857  1.00 19.77  ? 171  PHE C CG  1 
ATOM   8414  C CD1 . PHE C 1 178 ? 3.768   -9.518  -46.968  1.00 19.81  ? 171  PHE C CD1 1 
ATOM   8415  C CD2 . PHE C 1 178 ? 1.857   -8.906  -48.252  1.00 19.66  ? 171  PHE C CD2 1 
ATOM   8416  C CE1 . PHE C 1 178 ? 3.100   -10.638 -46.504  1.00 19.62  ? 171  PHE C CE1 1 
ATOM   8417  C CE2 . PHE C 1 178 ? 1.197   -10.026 -47.785  1.00 20.08  ? 171  PHE C CE2 1 
ATOM   8418  C CZ  . PHE C 1 178 ? 1.821   -10.895 -46.918  1.00 19.80  ? 171  PHE C CZ  1 
ATOM   8419  N N   . THR C 1 179 ? 6.691   -6.427  -50.102  1.00 18.28  ? 172  THR C N   1 
ATOM   8420  C CA  . THR C 1 179 ? 7.441   -5.217  -50.500  1.00 18.66  ? 172  THR C CA  1 
ATOM   8421  C C   . THR C 1 179 ? 7.624   -5.217  -52.040  1.00 18.59  ? 172  THR C C   1 
ATOM   8422  O O   . THR C 1 179 ? 7.788   -6.304  -52.649  1.00 16.39  ? 172  THR C O   1 
ATOM   8423  C CB  . THR C 1 179 ? 8.725   -5.120  -49.673  1.00 19.88  ? 172  THR C CB  1 
ATOM   8424  O OG1 . THR C 1 179 ? 8.384   -4.959  -48.292  1.00 19.62  ? 172  THR C OG1 1 
ATOM   8425  C CG2 . THR C 1 179 ? 9.613   -3.975  -50.115  1.00 20.84  ? 172  THR C CG2 1 
ATOM   8426  N N   . PHE C 1 180 ? 7.564   -4.037  -52.655  1.00 18.17  ? 173  PHE C N   1 
ATOM   8427  C CA  . PHE C 1 180 ? 7.834   -3.820  -54.092  1.00 19.18  ? 173  PHE C CA  1 
ATOM   8428  C C   . PHE C 1 180 ? 8.946   -2.792  -54.224  1.00 18.24  ? 173  PHE C C   1 
ATOM   8429  O O   . PHE C 1 180 ? 8.920   -1.795  -53.486  1.00 17.38  ? 173  PHE C O   1 
ATOM   8430  C CB  . PHE C 1 180 ? 6.593   -3.302  -54.815  1.00 20.91  ? 173  PHE C CB  1 
ATOM   8431  C CG  . PHE C 1 180 ? 5.556   -4.362  -55.052  1.00 22.71  ? 173  PHE C CG  1 
ATOM   8432  C CD1 . PHE C 1 180 ? 4.727   -4.768  -54.029  1.00 24.57  ? 173  PHE C CD1 1 
ATOM   8433  C CD2 . PHE C 1 180 ? 5.430   -4.972  -56.286  1.00 24.25  ? 173  PHE C CD2 1 
ATOM   8434  C CE1 . PHE C 1 180 ? 3.784   -5.755  -54.237  1.00 27.29  ? 173  PHE C CE1 1 
ATOM   8435  C CE2 . PHE C 1 180 ? 4.477   -5.957  -56.497  1.00 25.17  ? 173  PHE C CE2 1 
ATOM   8436  C CZ  . PHE C 1 180 ? 3.657   -6.349  -55.471  1.00 25.81  ? 173  PHE C CZ  1 
ATOM   8437  N N   A ILE C 1 181 ? 9.873   -3.029  -55.155  0.47 17.55  ? 174  ILE C N   1 
ATOM   8438  N N   B ILE C 1 181 ? 9.883   -3.036  -55.148  0.53 17.68  ? 174  ILE C N   1 
ATOM   8439  C CA  A ILE C 1 181 ? 10.970  -2.087  -55.506  0.47 17.04  ? 174  ILE C CA  1 
ATOM   8440  C CA  B ILE C 1 181 ? 10.981  -2.096  -55.506  0.53 17.22  ? 174  ILE C CA  1 
ATOM   8441  C C   A ILE C 1 181 ? 10.703  -1.530  -56.905  0.47 16.96  ? 174  ILE C C   1 
ATOM   8442  C C   B ILE C 1 181 ? 10.708  -1.534  -56.904  0.53 17.06  ? 174  ILE C C   1 
ATOM   8443  O O   A ILE C 1 181 ? 10.467  -2.323  -57.838  0.47 16.32  ? 174  ILE C O   1 
ATOM   8444  O O   B ILE C 1 181 ? 10.463  -2.326  -57.836  0.53 16.33  ? 174  ILE C O   1 
ATOM   8445  C CB  A ILE C 1 181 ? 12.338  -2.786  -55.442  0.47 16.98  ? 174  ILE C CB  1 
ATOM   8446  C CB  B ILE C 1 181 ? 12.358  -2.783  -55.419  0.53 17.34  ? 174  ILE C CB  1 
ATOM   8447  C CG1 A ILE C 1 181 ? 12.574  -3.458  -54.084  0.47 16.92  ? 174  ILE C CG1 1 
ATOM   8448  C CG1 B ILE C 1 181 ? 12.596  -3.380  -54.022  0.53 17.45  ? 174  ILE C CG1 1 
ATOM   8449  C CG2 A ILE C 1 181 ? 13.451  -1.818  -55.816  0.47 16.51  ? 174  ILE C CG2 1 
ATOM   8450  C CG2 B ILE C 1 181 ? 13.467  -1.820  -55.844  0.53 16.75  ? 174  ILE C CG2 1 
ATOM   8451  C CD1 A ILE C 1 181 ? 12.352  -2.574  -52.887  0.47 16.52  ? 174  ILE C CD1 1 
ATOM   8452  C CD1 B ILE C 1 181 ? 14.057  -3.712  -53.705  0.53 17.28  ? 174  ILE C CD1 1 
ATOM   8453  N N   . ALA C 1 182 ? 10.756  -0.207  -57.027  1.00 17.08  ? 175  ALA C N   1 
ATOM   8454  C CA  . ALA C 1 182 ? 10.746  0.525   -58.305  1.00 16.98  ? 175  ALA C CA  1 
ATOM   8455  C C   . ALA C 1 182 ? 12.010  1.371   -58.337  1.00 17.81  ? 175  ALA C C   1 
ATOM   8456  O O   . ALA C 1 182 ? 12.817  1.250   -57.397  1.00 18.03  ? 175  ALA C O   1 
ATOM   8457  C CB  . ALA C 1 182 ? 9.494   1.350   -58.421  1.00 17.57  ? 175  ALA C CB  1 
ATOM   8458  N N   . THR C 1 183 ? 12.200  2.163   -59.389  1.00 18.30  ? 176  THR C N   1 
ATOM   8459  C CA  . THR C 1 183 ? 13.410  2.997   -59.577  1.00 17.62  ? 176  THR C CA  1 
ATOM   8460  C C   . THR C 1 183 ? 12.980  4.459   -59.618  1.00 17.86  ? 176  THR C C   1 
ATOM   8461  O O   . THR C 1 183 ? 11.883  4.720   -60.074  1.00 17.16  ? 176  THR C O   1 
ATOM   8462  C CB  . THR C 1 183 ? 14.177  2.525   -60.814  1.00 17.45  ? 176  THR C CB  1 
ATOM   8463  O OG1 . THR C 1 183 ? 13.447  2.793   -62.007  1.00 15.56  ? 176  THR C OG1 1 
ATOM   8464  C CG2 . THR C 1 183 ? 14.471  1.042   -60.757  1.00 18.01  ? 176  THR C CG2 1 
ATOM   8465  N N   . SER C 1 184 ? 13.815  5.369   -59.135  1.00 18.92  ? 177  SER C N   1 
ATOM   8466  C CA  . SER C 1 184 ? 13.603  6.828   -59.278  1.00 20.17  ? 177  SER C CA  1 
ATOM   8467  C C   . SER C 1 184 ? 13.651  7.173   -60.763  1.00 20.47  ? 177  SER C C   1 
ATOM   8468  O O   . SER C 1 184 ? 14.335  6.440   -61.509  1.00 19.69  ? 177  SER C O   1 
ATOM   8469  C CB  . SER C 1 184 ? 14.622  7.624   -58.503  1.00 21.45  ? 177  SER C CB  1 
ATOM   8470  O OG  . SER C 1 184 ? 15.943  7.184   -58.791  1.00 21.01  ? 177  SER C OG  1 
ATOM   8471  N N   . GLY C 1 185 ? 12.922  8.224   -61.154  1.00 21.40  ? 178  GLY C N   1 
ATOM   8472  C CA  . GLY C 1 185 ? 12.670  8.602   -62.560  1.00 22.64  ? 178  GLY C CA  1 
ATOM   8473  C C   . GLY C 1 185 ? 11.629  7.714   -63.241  1.00 23.37  ? 178  GLY C C   1 
ATOM   8474  O O   . GLY C 1 185 ? 11.234  8.055   -64.360  1.00 21.21  ? 178  GLY C O   1 
ATOM   8475  N N   . ALA C 1 186 ? 11.192  6.622   -62.598  1.00 23.92  ? 179  ALA C N   1 
ATOM   8476  C CA  . ALA C 1 186 ? 10.294  5.598   -63.187  1.00 24.17  ? 179  ALA C CA  1 
ATOM   8477  C C   . ALA C 1 186 ? 8.880   6.173   -63.332  1.00 23.73  ? 179  ALA C C   1 
ATOM   8478  O O   . ALA C 1 186 ? 8.457   6.974   -62.495  1.00 25.50  ? 179  ALA C O   1 
ATOM   8479  C CB  . ALA C 1 186 ? 10.294  4.335   -62.359  1.00 25.22  ? 179  ALA C CB  1 
ATOM   8480  N N   . PHE C 1 187 ? 8.198   5.818   -64.414  1.00 22.71  ? 180  PHE C N   1 
ATOM   8481  C CA  . PHE C 1 187 ? 6.803   6.231   -64.686  1.00 21.21  ? 180  PHE C CA  1 
ATOM   8482  C C   . PHE C 1 187 ? 6.032   4.977   -65.069  1.00 20.05  ? 180  PHE C C   1 
ATOM   8483  O O   . PHE C 1 187 ? 6.385   4.379   -66.112  1.00 20.30  ? 180  PHE C O   1 
ATOM   8484  C CB  . PHE C 1 187 ? 6.738   7.289   -65.788  1.00 20.78  ? 180  PHE C CB  1 
ATOM   8485  C CG  . PHE C 1 187 ? 5.339   7.817   -65.923  1.00 20.85  ? 180  PHE C CG  1 
ATOM   8486  C CD1 . PHE C 1 187 ? 4.859   8.740   -65.021  1.00 22.59  ? 180  PHE C CD1 1 
ATOM   8487  C CD2 . PHE C 1 187 ? 4.456   7.282   -66.835  1.00 21.45  ? 180  PHE C CD2 1 
ATOM   8488  C CE1 . PHE C 1 187 ? 3.552   9.192   -65.090  1.00 23.15  ? 180  PHE C CE1 1 
ATOM   8489  C CE2 . PHE C 1 187 ? 3.145   7.733   -66.905  1.00 23.59  ? 180  PHE C CE2 1 
ATOM   8490  C CZ  . PHE C 1 187 ? 2.689   8.682   -66.022  1.00 22.78  ? 180  PHE C CZ  1 
ATOM   8491  N N   . HIS C 1 188 ? 5.055   4.586   -64.254  1.00 18.03  ? 181  HIS C N   1 
ATOM   8492  C CA  . HIS C 1 188 ? 4.277   3.335   -64.443  1.00 18.65  ? 181  HIS C CA  1 
ATOM   8493  C C   . HIS C 1 188 ? 2.768   3.624   -64.509  1.00 18.74  ? 181  HIS C C   1 
ATOM   8494  O O   . HIS C 1 188 ? 1.974   2.658   -64.497  1.00 17.09  ? 181  HIS C O   1 
ATOM   8495  C CB  . HIS C 1 188 ? 4.652   2.344   -63.343  1.00 18.83  ? 181  HIS C CB  1 
ATOM   8496  C CG  . HIS C 1 188 ? 6.106   2.031   -63.300  1.00 18.58  ? 181  HIS C CG  1 
ATOM   8497  N ND1 . HIS C 1 188 ? 6.735   1.352   -64.308  1.00 17.63  ? 181  HIS C ND1 1 
ATOM   8498  C CD2 . HIS C 1 188 ? 7.048   2.284   -62.364  1.00 18.45  ? 181  HIS C CD2 1 
ATOM   8499  C CE1 . HIS C 1 188 ? 8.020   1.218   -64.002  1.00 18.21  ? 181  HIS C CE1 1 
ATOM   8500  N NE2 . HIS C 1 188 ? 8.227   1.771   -62.814  1.00 17.97  ? 181  HIS C NE2 1 
ATOM   8501  N N   . GLY C 1 189 ? 2.394   4.902   -64.604  1.00 19.54  ? 182  GLY C N   1 
ATOM   8502  C CA  . GLY C 1 189 ? 0.989   5.337   -64.612  1.00 20.42  ? 182  GLY C CA  1 
ATOM   8503  C C   . GLY C 1 189 ? 0.573   6.110   -63.368  1.00 21.61  ? 182  GLY C C   1 
ATOM   8504  O O   . GLY C 1 189 ? 1.395   6.307   -62.462  1.00 21.26  ? 182  GLY C O   1 
ATOM   8505  N N   . LYS C 1 190 ? -0.704  6.487   -63.324  1.00 22.87  ? 183  LYS C N   1 
ATOM   8506  C CA  . LYS C 1 190 ? -1.244  7.503   -62.395  1.00 23.03  ? 183  LYS C CA  1 
ATOM   8507  C C   . LYS C 1 190 ? -2.478  6.974   -61.639  1.00 21.97  ? 183  LYS C C   1 
ATOM   8508  O O   . LYS C 1 190 ? -2.950  7.683   -60.733  1.00 20.32  ? 183  LYS C O   1 
ATOM   8509  C CB  . LYS C 1 190 ? -1.536  8.767   -63.207  1.00 24.35  ? 183  LYS C CB  1 
ATOM   8510  C CG  . LYS C 1 190 ? -0.297  9.427   -63.795  1.00 24.28  ? 183  LYS C CG  1 
ATOM   8511  C CD  . LYS C 1 190 ? -0.165  10.829  -63.326  1.00 25.67  ? 183  LYS C CD  1 
ATOM   8512  C CE  . LYS C 1 190 ? 0.960   11.571  -63.994  1.00 27.41  ? 183  LYS C CE  1 
ATOM   8513  N NZ  . LYS C 1 190 ? 0.457   12.652  -64.872  1.00 31.12  ? 183  LYS C NZ  1 
ATOM   8514  N N   . SER C 1 191 ? -2.972  5.775   -61.942  1.00 20.83  ? 184  SER C N   1 
ATOM   8515  C CA  . SER C 1 191 ? -3.926  5.076   -61.046  1.00 22.34  ? 184  SER C CA  1 
ATOM   8516  C C   . SER C 1 191 ? -3.175  4.769   -59.752  1.00 21.32  ? 184  SER C C   1 
ATOM   8517  O O   . SER C 1 191 ? -1.945  4.611   -59.823  1.00 19.79  ? 184  SER C O   1 
ATOM   8518  C CB  . SER C 1 191 ? -4.496  3.845   -61.675  1.00 23.61  ? 184  SER C CB  1 
ATOM   8519  O OG  . SER C 1 191 ? -3.463  2.937   -62.004  1.00 25.86  ? 184  SER C OG  1 
ATOM   8520  N N   . LEU C 1 192 ? -3.866  4.720   -58.621  1.00 21.33  ? 185  LEU C N   1 
ATOM   8521  C CA  . LEU C 1 192 ? -3.183  4.796   -57.296  1.00 23.13  ? 185  LEU C CA  1 
ATOM   8522  C C   . LEU C 1 192 ? -2.286  3.575   -57.038  1.00 23.55  ? 185  LEU C C   1 
ATOM   8523  O O   . LEU C 1 192 ? -1.310  3.735   -56.301  1.00 22.00  ? 185  LEU C O   1 
ATOM   8524  C CB  . LEU C 1 192 ? -4.214  4.995   -56.187  1.00 22.79  ? 185  LEU C CB  1 
ATOM   8525  C CG  . LEU C 1 192 ? -4.865  6.378   -56.213  1.00 24.60  ? 185  LEU C CG  1 
ATOM   8526  C CD1 . LEU C 1 192 ? -6.219  6.390   -55.486  1.00 24.67  ? 185  LEU C CD1 1 
ATOM   8527  C CD2 . LEU C 1 192 ? -3.904  7.435   -55.657  1.00 23.12  ? 185  LEU C CD2 1 
ATOM   8528  N N   . GLY C 1 193 ? -2.577  2.406   -57.612  1.00 25.12  ? 186  GLY C N   1 
ATOM   8529  C CA  . GLY C 1 193 ? -1.660  1.251   -57.518  1.00 23.74  ? 186  GLY C CA  1 
ATOM   8530  C C   . GLY C 1 193 ? -0.391  1.494   -58.324  1.00 22.75  ? 186  GLY C C   1 
ATOM   8531  O O   . GLY C 1 193 ? 0.735   1.330   -57.794  1.00 22.26  ? 186  GLY C O   1 
ATOM   8532  N N   . ALA C 1 194 ? -0.575  1.903   -59.570  1.00 20.88  ? 187  ALA C N   1 
ATOM   8533  C CA  . ALA C 1 194 ? 0.517   2.237   -60.503  1.00 20.60  ? 187  ALA C CA  1 
ATOM   8534  C C   . ALA C 1 194 ? 1.334   3.397   -59.937  1.00 18.69  ? 187  ALA C C   1 
ATOM   8535  O O   . ALA C 1 194 ? 2.551   3.330   -60.041  1.00 19.40  ? 187  ALA C O   1 
ATOM   8536  C CB  . ALA C 1 194 ? -0.060  2.572   -61.860  1.00 21.40  ? 187  ALA C CB  1 
ATOM   8537  N N   . LEU C 1 195 ? 0.690   4.413   -59.361  1.00 18.67  ? 188  LEU C N   1 
ATOM   8538  C CA  . LEU C 1 195 ? 1.367   5.665   -58.938  1.00 18.84  ? 188  LEU C CA  1 
ATOM   8539  C C   . LEU C 1 195 ? 2.267   5.371   -57.727  1.00 19.07  ? 188  LEU C C   1 
ATOM   8540  O O   . LEU C 1 195 ? 3.203   6.142   -57.484  1.00 18.82  ? 188  LEU C O   1 
ATOM   8541  C CB  . LEU C 1 195 ? 0.311   6.722   -58.604  1.00 18.84  ? 188  LEU C CB  1 
ATOM   8542  C CG  . LEU C 1 195 ? 0.885   8.052   -58.114  1.00 19.35  ? 188  LEU C CG  1 
ATOM   8543  C CD1 . LEU C 1 195 ? 1.687   8.729   -59.215  1.00 18.76  ? 188  LEU C CD1 1 
ATOM   8544  C CD2 . LEU C 1 195 ? -0.199  8.960   -57.584  1.00 20.28  ? 188  LEU C CD2 1 
ATOM   8545  N N   . SER C 1 196 ? 1.994   4.288   -56.993  1.00 17.55  ? 189  SER C N   1 
ATOM   8546  C CA  . SER C 1 196 ? 2.847   3.781   -55.895  1.00 16.67  ? 189  SER C CA  1 
ATOM   8547  C C   . SER C 1 196 ? 4.223   3.377   -56.429  1.00 16.96  ? 189  SER C C   1 
ATOM   8548  O O   . SER C 1 196 ? 5.202   3.463   -55.654  1.00 17.90  ? 189  SER C O   1 
ATOM   8549  C CB  . SER C 1 196 ? 2.176   2.652   -55.175  1.00 16.89  ? 189  SER C CB  1 
ATOM   8550  O OG  . SER C 1 196 ? 0.923   3.065   -54.670  1.00 16.52  ? 189  SER C OG  1 
ATOM   8551  N N   . ALA C 1 197 ? 4.309   2.948   -57.689  1.00 16.65  ? 190  ALA C N   1 
ATOM   8552  C CA  . ALA C 1 197 ? 5.577   2.588   -58.375  1.00 17.00  ? 190  ALA C CA  1 
ATOM   8553  C C   . ALA C 1 197 ? 6.149   3.813   -59.118  1.00 17.35  ? 190  ALA C C   1 
ATOM   8554  O O   . ALA C 1 197 ? 7.377   4.022   -59.075  1.00 17.02  ? 190  ALA C O   1 
ATOM   8555  C CB  . ALA C 1 197 ? 5.339   1.411   -59.293  1.00 17.10  ? 190  ALA C CB  1 
ATOM   8556  N N   . THR C 1 198 ? 5.306   4.621   -59.772  1.00 18.42  ? 191  THR C N   1 
ATOM   8557  C CA  . THR C 1 198 ? 5.723   5.921   -60.367  1.00 17.90  ? 191  THR C CA  1 
ATOM   8558  C C   . THR C 1 198 ? 6.560   6.673   -59.316  1.00 18.05  ? 191  THR C C   1 
ATOM   8559  O O   . THR C 1 198 ? 6.266   6.543   -58.149  1.00 19.51  ? 191  THR C O   1 
ATOM   8560  C CB  . THR C 1 198 ? 4.503   6.678   -60.907  1.00 16.97  ? 191  THR C CB  1 
ATOM   8561  O OG1 . THR C 1 198 ? 3.994   5.904   -61.994  1.00 15.71  ? 191  THR C OG1 1 
ATOM   8562  C CG2 . THR C 1 198 ? 4.826   8.082   -61.373  1.00 16.99  ? 191  THR C CG2 1 
ATOM   8563  N N   . ALA C 1 199 ? 7.602   7.386   -59.712  1.00 18.90  ? 192  ALA C N   1 
ATOM   8564  C CA  . ALA C 1 199 ? 8.643   7.860   -58.786  1.00 20.62  ? 192  ALA C CA  1 
ATOM   8565  C C   . ALA C 1 199 ? 8.672   9.377   -58.680  1.00 22.50  ? 192  ALA C C   1 
ATOM   8566  O O   . ALA C 1 199 ? 9.364   9.846   -57.812  1.00 25.04  ? 192  ALA C O   1 
ATOM   8567  C CB  . ALA C 1 199 ? 9.989   7.341   -59.216  1.00 20.09  ? 192  ALA C CB  1 
ATOM   8568  N N   . LYS C 1 200 ? 8.009   10.133  -59.532  1.00 24.93  ? 193  LYS C N   1 
ATOM   8569  C CA  . LYS C 1 200 ? 8.174   11.606  -59.478  1.00 27.70  ? 193  LYS C CA  1 
ATOM   8570  C C   . LYS C 1 200 ? 7.354   12.130  -58.293  1.00 27.00  ? 193  LYS C C   1 
ATOM   8571  O O   . LYS C 1 200 ? 6.175   11.777  -58.180  1.00 25.79  ? 193  LYS C O   1 
ATOM   8572  C CB  . LYS C 1 200 ? 7.804   12.272  -60.805  1.00 31.89  ? 193  LYS C CB  1 
ATOM   8573  C CG  . LYS C 1 200 ? 7.789   13.792  -60.747  1.00 35.30  ? 193  LYS C CG  1 
ATOM   8574  C CD  . LYS C 1 200 ? 7.139   14.375  -61.951  1.00 40.41  ? 193  LYS C CD  1 
ATOM   8575  C CE  . LYS C 1 200 ? 7.933   15.469  -62.632  1.00 45.79  ? 193  LYS C CE  1 
ATOM   8576  N NZ  . LYS C 1 200 ? 9.394   15.247  -62.556  1.00 52.45  ? 193  LYS C NZ  1 
ATOM   8577  N N   . SER C 1 201 ? 7.992   12.946  -57.457  1.00 27.75  ? 194  SER C N   1 
ATOM   8578  C CA  . SER C 1 201 ? 7.439   13.542  -56.219  1.00 27.66  ? 194  SER C CA  1 
ATOM   8579  C C   . SER C 1 201 ? 6.145   14.293  -56.508  1.00 25.91  ? 194  SER C C   1 
ATOM   8580  O O   . SER C 1 201 ? 5.152   14.018  -55.821  1.00 28.53  ? 194  SER C O   1 
ATOM   8581  C CB  . SER C 1 201 ? 8.421   14.472  -55.580  1.00 28.55  ? 194  SER C CB  1 
ATOM   8582  O OG  . SER C 1 201 ? 7.826   15.046  -54.420  1.00 32.64  ? 194  SER C OG  1 
ATOM   8583  N N   . THR C 1 202 ? 6.178   15.239  -57.442  1.00 24.97  ? 195  THR C N   1 
ATOM   8584  C CA  . THR C 1 202 ? 5.041   16.157  -57.753  1.00 25.37  ? 195  THR C CA  1 
ATOM   8585  C C   . THR C 1 202 ? 3.804   15.355  -58.187  1.00 24.08  ? 195  THR C C   1 
ATOM   8586  O O   . THR C 1 202 ? 2.707   15.866  -58.059  1.00 22.70  ? 195  THR C O   1 
ATOM   8587  C CB  . THR C 1 202 ? 5.392   17.197  -58.833  1.00 26.14  ? 195  THR C CB  1 
ATOM   8588  O OG1 . THR C 1 202 ? 5.530   16.533  -60.085  1.00 25.16  ? 195  THR C OG1 1 
ATOM   8589  C CG2 . THR C 1 202 ? 6.661   17.965  -58.545  1.00 27.25  ? 195  THR C CG2 1 
ATOM   8590  N N   . PHE C 1 203 ? 3.977   14.130  -58.668  1.00 23.58  ? 196  PHE C N   1 
ATOM   8591  C CA  . PHE C 1 203 ? 2.865   13.251  -59.104  1.00 23.06  ? 196  PHE C CA  1 
ATOM   8592  C C   . PHE C 1 203 ? 2.322   12.437  -57.929  1.00 21.94  ? 196  PHE C C   1 
ATOM   8593  O O   . PHE C 1 203 ? 1.205   11.930  -58.069  1.00 22.87  ? 196  PHE C O   1 
ATOM   8594  C CB  . PHE C 1 203 ? 3.333   12.333  -60.236  1.00 23.96  ? 196  PHE C CB  1 
ATOM   8595  C CG  . PHE C 1 203 ? 3.567   13.013  -61.561  1.00 24.62  ? 196  PHE C CG  1 
ATOM   8596  C CD1 . PHE C 1 203 ? 3.087   14.296  -61.813  1.00 25.72  ? 196  PHE C CD1 1 
ATOM   8597  C CD2 . PHE C 1 203 ? 4.209   12.346  -62.592  1.00 24.08  ? 196  PHE C CD2 1 
ATOM   8598  C CE1 . PHE C 1 203 ? 3.263   14.902  -63.053  1.00 23.30  ? 196  PHE C CE1 1 
ATOM   8599  C CE2 . PHE C 1 203 ? 4.362   12.954  -63.830  1.00 22.66  ? 196  PHE C CE2 1 
ATOM   8600  C CZ  . PHE C 1 203 ? 3.884   14.223  -64.058  1.00 22.09  ? 196  PHE C CZ  1 
ATOM   8601  N N   . ARG C 1 204 ? 3.061   12.324  -56.823  1.00 21.95  ? 197  ARG C N   1 
ATOM   8602  C CA  . ARG C 1 204 ? 2.746   11.369  -55.724  1.00 22.51  ? 197  ARG C CA  1 
ATOM   8603  C C   . ARG C 1 204 ? 2.296   12.084  -54.445  1.00 24.04  ? 197  ARG C C   1 
ATOM   8604  O O   . ARG C 1 204 ? 1.362   11.572  -53.792  1.00 24.65  ? 197  ARG C O   1 
ATOM   8605  C CB  . ARG C 1 204 ? 3.970   10.512  -55.402  1.00 21.12  ? 197  ARG C CB  1 
ATOM   8606  C CG  . ARG C 1 204 ? 4.356   9.532   -56.497  1.00 19.65  ? 197  ARG C CG  1 
ATOM   8607  C CD  . ARG C 1 204 ? 5.797   9.105   -56.362  1.00 18.35  ? 197  ARG C CD  1 
ATOM   8608  N NE  . ARG C 1 204 ? 6.095   8.605   -55.031  1.00 19.27  ? 197  ARG C NE  1 
ATOM   8609  C CZ  . ARG C 1 204 ? 5.861   7.373   -54.575  1.00 17.87  ? 197  ARG C CZ  1 
ATOM   8610  N NH1 . ARG C 1 204 ? 5.338   6.446   -55.349  1.00 18.20  ? 197  ARG C NH1 1 
ATOM   8611  N NH2 . ARG C 1 204 ? 6.172   7.039   -53.348  1.00 16.03  ? 197  ARG C NH2 1 
ATOM   8612  N N   . LYS C 1 205 ? 2.960   13.185  -54.076  1.00 26.85  ? 198  LYS C N   1 
ATOM   8613  C CA  . LYS C 1 205 ? 2.839   13.834  -52.743  1.00 28.68  ? 198  LYS C CA  1 
ATOM   8614  C C   . LYS C 1 205 ? 1.381   14.166  -52.447  1.00 26.92  ? 198  LYS C C   1 
ATOM   8615  O O   . LYS C 1 205 ? 0.906   13.831  -51.369  1.00 23.50  ? 198  LYS C O   1 
ATOM   8616  C CB  . LYS C 1 205 ? 3.735   15.073  -52.632  1.00 33.01  ? 198  LYS C CB  1 
ATOM   8617  C CG  . LYS C 1 205 ? 5.034   14.847  -51.866  1.00 38.16  ? 198  LYS C CG  1 
ATOM   8618  C CD  . LYS C 1 205 ? 6.050   15.991  -51.934  1.00 41.33  ? 198  LYS C CD  1 
ATOM   8619  C CE  . LYS C 1 205 ? 5.692   17.199  -51.098  1.00 42.24  ? 198  LYS C CE  1 
ATOM   8620  N NZ  . LYS C 1 205 ? 5.633   16.831  -49.667  1.00 46.92  ? 198  LYS C NZ  1 
ATOM   8621  N N   . PRO C 1 206 ? 0.620   14.808  -53.368  1.00 26.34  ? 199  PRO C N   1 
ATOM   8622  C CA  . PRO C 1 206 ? -0.775  15.157  -53.089  1.00 26.90  ? 199  PRO C CA  1 
ATOM   8623  C C   . PRO C 1 206 ? -1.665  13.965  -52.696  1.00 26.99  ? 199  PRO C C   1 
ATOM   8624  O O   . PRO C 1 206 ? -2.654  14.180  -51.987  1.00 28.77  ? 199  PRO C O   1 
ATOM   8625  C CB  . PRO C 1 206 ? -1.259  15.795  -54.401  1.00 25.96  ? 199  PRO C CB  1 
ATOM   8626  C CG  . PRO C 1 206 ? 0.002   16.305  -55.039  1.00 25.24  ? 199  PRO C CG  1 
ATOM   8627  C CD  . PRO C 1 206 ? 1.044   15.262  -54.693  1.00 25.33  ? 199  PRO C CD  1 
ATOM   8628  N N   . PHE C 1 207 ? -1.281  12.755  -53.126  1.00 25.07  ? 200  PHE C N   1 
ATOM   8629  C CA  . PHE C 1 207 ? -2.141  11.544  -53.124  1.00 25.27  ? 200  PHE C CA  1 
ATOM   8630  C C   . PHE C 1 207 ? -1.683  10.553  -52.048  1.00 25.55  ? 200  PHE C C   1 
ATOM   8631  O O   . PHE C 1 207 ? -2.322  9.500   -51.855  1.00 24.46  ? 200  PHE C O   1 
ATOM   8632  C CB  . PHE C 1 207 ? -2.183  10.981  -54.546  1.00 22.81  ? 200  PHE C CB  1 
ATOM   8633  C CG  . PHE C 1 207 ? -2.515  12.037  -55.568  1.00 22.06  ? 200  PHE C CG  1 
ATOM   8634  C CD1 . PHE C 1 207 ? -3.790  12.581  -55.631  1.00 21.55  ? 200  PHE C CD1 1 
ATOM   8635  C CD2 . PHE C 1 207 ? -1.549  12.524  -56.443  1.00 22.66  ? 200  PHE C CD2 1 
ATOM   8636  C CE1 . PHE C 1 207 ? -4.102  13.558  -56.566  1.00 21.98  ? 200  PHE C CE1 1 
ATOM   8637  C CE2 . PHE C 1 207 ? -1.856  13.519  -57.361  1.00 21.56  ? 200  PHE C CE2 1 
ATOM   8638  C CZ  . PHE C 1 207 ? -3.132  14.037  -57.416  1.00 21.62  ? 200  PHE C CZ  1 
ATOM   8639  N N   . MET C 1 208 ? -0.627  10.887  -51.325  1.00 25.82  ? 201  MET C N   1 
ATOM   8640  C CA  . MET C 1 208 ? -0.176  10.022  -50.212  1.00 27.10  ? 201  MET C CA  1 
ATOM   8641  C C   . MET C 1 208 ? -1.183  10.120  -49.072  1.00 26.71  ? 201  MET C C   1 
ATOM   8642  O O   . MET C 1 208 ? -1.844  11.147  -48.912  1.00 26.32  ? 201  MET C O   1 
ATOM   8643  C CB  . MET C 1 208 ? 1.215   10.426  -49.727  1.00 28.58  ? 201  MET C CB  1 
ATOM   8644  C CG  . MET C 1 208 ? 2.276   10.220  -50.790  1.00 28.82  ? 201  MET C CG  1 
ATOM   8645  S SD  . MET C 1 208 ? 3.827   10.923  -50.272  1.00 28.03  ? 201  MET C SD  1 
ATOM   8646  C CE  . MET C 1 208 ? 4.796   10.537  -51.713  1.00 27.71  ? 201  MET C CE  1 
ATOM   8647  N N   . PRO C 1 209 ? -1.351  9.056   -48.255  1.00 24.81  ? 202  PRO C N   1 
ATOM   8648  C CA  . PRO C 1 209 ? -0.582  7.819   -48.393  1.00 24.01  ? 202  PRO C CA  1 
ATOM   8649  C C   . PRO C 1 209 ? -0.986  6.897   -49.554  1.00 23.43  ? 202  PRO C C   1 
ATOM   8650  O O   . PRO C 1 209 ? -2.170  6.633   -49.743  1.00 21.61  ? 202  PRO C O   1 
ATOM   8651  C CB  . PRO C 1 209 ? -0.900  7.067   -47.107  1.00 24.05  ? 202  PRO C CB  1 
ATOM   8652  C CG  . PRO C 1 209 ? -2.289  7.542   -46.746  1.00 24.13  ? 202  PRO C CG  1 
ATOM   8653  C CD  . PRO C 1 209 ? -2.307  9.000   -47.150  1.00 24.01  ? 202  PRO C CD  1 
ATOM   8654  N N   . LEU C 1 210 ? 0.026   6.416   -50.281  1.00 21.49  ? 203  LEU C N   1 
ATOM   8655  C CA  . LEU C 1 210 ? -0.124  5.469   -51.408  1.00 19.89  ? 203  LEU C CA  1 
ATOM   8656  C C   . LEU C 1 210 ? -0.014  4.049   -50.872  1.00 18.21  ? 203  LEU C C   1 
ATOM   8657  O O   . LEU C 1 210 ? -0.050  3.896   -49.647  1.00 17.78  ? 203  LEU C O   1 
ATOM   8658  C CB  . LEU C 1 210 ? 0.954   5.797   -52.439  1.00 21.60  ? 203  LEU C CB  1 
ATOM   8659  C CG  . LEU C 1 210 ? 0.817   7.186   -53.065  1.00 21.81  ? 203  LEU C CG  1 
ATOM   8660  C CD1 . LEU C 1 210 ? 1.972   7.445   -54.003  1.00 22.04  ? 203  LEU C CD1 1 
ATOM   8661  C CD2 . LEU C 1 210 ? -0.507  7.349   -53.789  1.00 20.97  ? 203  LEU C CD2 1 
ATOM   8662  N N   . LEU C 1 211 ? 0.050   3.047   -51.742  1.00 18.09  ? 204  LEU C N   1 
ATOM   8663  C CA  . LEU C 1 211 ? 0.144   1.641   -51.293  1.00 19.85  ? 204  LEU C CA  1 
ATOM   8664  C C   . LEU C 1 211 ? 1.351   1.544   -50.388  1.00 22.42  ? 204  LEU C C   1 
ATOM   8665  O O   . LEU C 1 211 ? 2.415   2.077   -50.711  1.00 23.74  ? 204  LEU C O   1 
ATOM   8666  C CB  . LEU C 1 211 ? 0.325   0.678   -52.459  1.00 20.22  ? 204  LEU C CB  1 
ATOM   8667  C CG  . LEU C 1 211 ? -0.898  0.445   -53.337  1.00 22.95  ? 204  LEU C CG  1 
ATOM   8668  C CD1 . LEU C 1 211 ? -0.573  -0.563  -54.429  1.00 23.28  ? 204  LEU C CD1 1 
ATOM   8669  C CD2 . LEU C 1 211 ? -2.111  -0.016  -52.533  1.00 23.38  ? 204  LEU C CD2 1 
ATOM   8670  N N   . PRO C 1 212 ? 1.234   0.859   -49.236  1.00 24.60  ? 205  PRO C N   1 
ATOM   8671  C CA  . PRO C 1 212 ? 2.398   0.635   -48.388  1.00 25.56  ? 205  PRO C CA  1 
ATOM   8672  C C   . PRO C 1 212 ? 3.356   -0.380  -49.041  1.00 25.62  ? 205  PRO C C   1 
ATOM   8673  O O   . PRO C 1 212 ? 2.935   -1.154  -49.916  1.00 26.63  ? 205  PRO C O   1 
ATOM   8674  C CB  . PRO C 1 212 ? 1.798   0.178   -47.048  1.00 25.69  ? 205  PRO C CB  1 
ATOM   8675  C CG  . PRO C 1 212 ? 0.413   -0.344  -47.371  1.00 25.56  ? 205  PRO C CG  1 
ATOM   8676  C CD  . PRO C 1 212 ? -0.000  0.283   -48.692  1.00 25.72  ? 205  PRO C CD  1 
ATOM   8677  N N   . GLY C 1 213 ? 4.632   -0.308  -48.653  1.00 24.00  ? 206  GLY C N   1 
ATOM   8678  C CA  . GLY C 1 213 ? 5.644   -1.325  -48.977  1.00 23.48  ? 206  GLY C CA  1 
ATOM   8679  C C   . GLY C 1 213 ? 6.277   -1.099  -50.328  1.00 22.28  ? 206  GLY C C   1 
ATOM   8680  O O   . GLY C 1 213 ? 6.816   -2.078  -50.864  1.00 22.58  ? 206  GLY C O   1 
ATOM   8681  N N   . PHE C 1 214 ? 6.217   0.134   -50.846  1.00 22.41  ? 207  PHE C N   1 
ATOM   8682  C CA  . PHE C 1 214 ? 6.836   0.546   -52.135  1.00 22.65  ? 207  PHE C CA  1 
ATOM   8683  C C   . PHE C 1 214 ? 8.073   1.395   -51.843  1.00 23.67  ? 207  PHE C C   1 
ATOM   8684  O O   . PHE C 1 214 ? 7.972   2.422   -51.131  1.00 22.52  ? 207  PHE C O   1 
ATOM   8685  C CB  . PHE C 1 214 ? 5.825   1.255   -53.042  1.00 22.41  ? 207  PHE C CB  1 
ATOM   8686  C CG  . PHE C 1 214 ? 4.930   0.320   -53.823  1.00 20.40  ? 207  PHE C CG  1 
ATOM   8687  C CD1 . PHE C 1 214 ? 3.921   -0.395  -53.189  1.00 19.91  ? 207  PHE C CD1 1 
ATOM   8688  C CD2 . PHE C 1 214 ? 5.113   0.130   -55.181  1.00 19.57  ? 207  PHE C CD2 1 
ATOM   8689  C CE1 . PHE C 1 214 ? 3.112   -1.272  -53.889  1.00 18.43  ? 207  PHE C CE1 1 
ATOM   8690  C CE2 . PHE C 1 214 ? 4.298   -0.736  -55.885  1.00 18.86  ? 207  PHE C CE2 1 
ATOM   8691  C CZ  . PHE C 1 214 ? 3.308   -1.437  -55.235  1.00 19.03  ? 207  PHE C CZ  1 
ATOM   8692  N N   A ARG C 1 215 ? 9.221   0.951   -52.366  0.49 24.29  ? 208  ARG C N   1 
ATOM   8693  N N   B ARG C 1 215 ? 9.211   0.966   -52.398  0.51 24.34  ? 208  ARG C N   1 
ATOM   8694  C CA  A ARG C 1 215 ? 10.569  1.531   -52.109  0.49 24.09  ? 208  ARG C CA  1 
ATOM   8695  C CA  B ARG C 1 215 ? 10.567  1.521   -52.128  0.51 24.19  ? 208  ARG C CA  1 
ATOM   8696  C C   A ARG C 1 215 ? 11.271  1.734   -53.453  0.49 23.60  ? 208  ARG C C   1 
ATOM   8697  C C   B ARG C 1 215 ? 11.274  1.732   -53.463  0.51 23.66  ? 208  ARG C C   1 
ATOM   8698  O O   A ARG C 1 215 ? 11.073  0.898   -54.361  0.49 23.45  ? 208  ARG C O   1 
ATOM   8699  O O   B ARG C 1 215 ? 11.087  0.897   -54.370  0.51 23.48  ? 208  ARG C O   1 
ATOM   8700  C CB  A ARG C 1 215 ? 11.399  0.610   -51.208  0.49 24.34  ? 208  ARG C CB  1 
ATOM   8701  C CB  B ARG C 1 215 ? 11.405  0.574   -51.261  0.51 24.52  ? 208  ARG C CB  1 
ATOM   8702  C CG  A ARG C 1 215 ? 10.845  0.379   -49.803  0.49 25.67  ? 208  ARG C CG  1 
ATOM   8703  C CG  B ARG C 1 215 ? 10.718  0.081   -49.994  0.51 25.95  ? 208  ARG C CG  1 
ATOM   8704  C CD  A ARG C 1 215 ? 11.490  -0.854  -49.171  0.49 25.91  ? 208  ARG C CD  1 
ATOM   8705  C CD  B ARG C 1 215 ? 10.662  1.156   -48.924  0.51 26.16  ? 208  ARG C CD  1 
ATOM   8706  N NE  A ARG C 1 215 ? 11.641  -0.926  -47.719  0.49 24.03  ? 208  ARG C NE  1 
ATOM   8707  N NE  B ARG C 1 215 ? 10.052  0.667   -47.701  0.51 26.10  ? 208  ARG C NE  1 
ATOM   8708  C CZ  A ARG C 1 215 ? 10.734  -1.428  -46.899  0.49 24.62  ? 208  ARG C CZ  1 
ATOM   8709  C CZ  B ARG C 1 215 ? 8.760   0.778   -47.397  0.51 26.73  ? 208  ARG C CZ  1 
ATOM   8710  N NH1 A ARG C 1 215 ? 9.571   -1.841  -47.374  0.49 25.87  ? 208  ARG C NH1 1 
ATOM   8711  N NH1 B ARG C 1 215 ? 7.925   1.373   -48.233  0.51 26.00  ? 208  ARG C NH1 1 
ATOM   8712  N NH2 A ARG C 1 215 ? 10.974  -1.498  -45.604  0.49 23.94  ? 208  ARG C NH2 1 
ATOM   8713  N NH2 B ARG C 1 215 ? 8.313   0.305   -46.242  0.51 27.21  ? 208  ARG C NH2 1 
ATOM   8714  N N   . HIS C 1 216 ? 12.068  2.795   -53.562  1.00 23.38  ? 209  HIS C N   1 
ATOM   8715  C CA  . HIS C 1 216 ? 12.719  3.212   -54.829  1.00 22.14  ? 209  HIS C CA  1 
ATOM   8716  C C   . HIS C 1 216 ? 14.239  3.177   -54.679  1.00 22.02  ? 209  HIS C C   1 
ATOM   8717  O O   . HIS C 1 216 ? 14.767  3.692   -53.689  1.00 23.44  ? 209  HIS C O   1 
ATOM   8718  C CB  . HIS C 1 216 ? 12.153  4.569   -55.271  1.00 21.28  ? 209  HIS C CB  1 
ATOM   8719  C CG  . HIS C 1 216 ? 10.739  4.495   -55.743  1.00 19.77  ? 209  HIS C CG  1 
ATOM   8720  N ND1 . HIS C 1 216 ? 9.665   4.557   -54.886  1.00 19.70  ? 209  HIS C ND1 1 
ATOM   8721  C CD2 . HIS C 1 216 ? 10.219  4.372   -56.981  1.00 19.96  ? 209  HIS C CD2 1 
ATOM   8722  C CE1 . HIS C 1 216 ? 8.546   4.463   -55.567  1.00 19.21  ? 209  HIS C CE1 1 
ATOM   8723  N NE2 . HIS C 1 216 ? 8.854   4.352   -56.849  1.00 19.70  ? 209  HIS C NE2 1 
ATOM   8724  N N   . VAL C 1 217 ? 14.900  2.576   -55.663  1.00 23.25  ? 210  VAL C N   1 
ATOM   8725  C CA  . VAL C 1 217 ? 16.377  2.559   -55.815  1.00 23.47  ? 210  VAL C CA  1 
ATOM   8726  C C   . VAL C 1 217 ? 16.721  3.349   -57.082  1.00 24.63  ? 210  VAL C C   1 
ATOM   8727  O O   . VAL C 1 217 ? 15.831  3.633   -57.879  1.00 25.77  ? 210  VAL C O   1 
ATOM   8728  C CB  . VAL C 1 217 ? 16.888  1.105   -55.824  1.00 23.76  ? 210  VAL C CB  1 
ATOM   8729  C CG1 . VAL C 1 217 ? 16.552  0.408   -54.515  1.00 22.92  ? 210  VAL C CG1 1 
ATOM   8730  C CG2 . VAL C 1 217 ? 16.371  0.290   -57.004  1.00 23.07  ? 210  VAL C CG2 1 
ATOM   8731  N N   . PRO C 1 218 ? 17.984  3.818   -57.259  1.00 23.78  ? 211  PRO C N   1 
ATOM   8732  C CA  . PRO C 1 218 ? 18.413  4.444   -58.504  1.00 22.89  ? 211  PRO C CA  1 
ATOM   8733  C C   . PRO C 1 218 ? 18.337  3.450   -59.669  1.00 24.13  ? 211  PRO C C   1 
ATOM   8734  O O   . PRO C 1 218 ? 18.635  2.274   -59.473  1.00 24.66  ? 211  PRO C O   1 
ATOM   8735  C CB  . PRO C 1 218 ? 19.875  4.847   -58.261  1.00 24.18  ? 211  PRO C CB  1 
ATOM   8736  C CG  . PRO C 1 218 ? 19.996  4.899   -56.760  1.00 23.65  ? 211  PRO C CG  1 
ATOM   8737  C CD  . PRO C 1 218 ? 19.046  3.840   -56.241  1.00 22.96  ? 211  PRO C CD  1 
ATOM   8738  N N   . PHE C 1 219 ? 17.918  3.946   -60.835  1.00 23.43  ? 212  PHE C N   1 
ATOM   8739  C CA  . PHE C 1 219 ? 17.829  3.176   -62.097  1.00 22.67  ? 212  PHE C CA  1 
ATOM   8740  C C   . PHE C 1 219 ? 19.246  2.950   -62.610  1.00 23.01  ? 212  PHE C C   1 
ATOM   8741  O O   . PHE C 1 219 ? 20.026  3.916   -62.603  1.00 22.94  ? 212  PHE C O   1 
ATOM   8742  C CB  . PHE C 1 219 ? 16.988  3.928   -63.128  1.00 22.18  ? 212  PHE C CB  1 
ATOM   8743  C CG  . PHE C 1 219 ? 16.760  3.162   -64.404  1.00 21.61  ? 212  PHE C CG  1 
ATOM   8744  C CD1 . PHE C 1 219 ? 15.993  2.012   -64.420  1.00 19.98  ? 212  PHE C CD1 1 
ATOM   8745  C CD2 . PHE C 1 219 ? 17.355  3.574   -65.585  1.00 21.93  ? 212  PHE C CD2 1 
ATOM   8746  C CE1 . PHE C 1 219 ? 15.822  1.297   -65.590  1.00 20.74  ? 212  PHE C CE1 1 
ATOM   8747  C CE2 . PHE C 1 219 ? 17.169  2.866   -66.763  1.00 21.97  ? 212  PHE C CE2 1 
ATOM   8748  C CZ  . PHE C 1 219 ? 16.404  1.724   -66.765  1.00 21.31  ? 212  PHE C CZ  1 
ATOM   8749  N N   . GLY C 1 220 ? 19.555  1.723   -63.030  1.00 23.91  ? 213  GLY C N   1 
ATOM   8750  C CA  . GLY C 1 220 ? 20.832  1.363   -63.687  1.00 25.29  ? 213  GLY C CA  1 
ATOM   8751  C C   . GLY C 1 220 ? 21.952  1.133   -62.692  1.00 25.47  ? 213  GLY C C   1 
ATOM   8752  O O   . GLY C 1 220 ? 23.106  1.128   -63.123  1.00 25.81  ? 213  GLY C O   1 
ATOM   8753  N N   . ASN C 1 221 ? 21.606  0.938   -61.406  1.00 28.03  ? 214  ASN C N   1 
ATOM   8754  C CA  . ASN C 1 221 ? 22.537  0.731   -60.260  1.00 24.66  ? 214  ASN C CA  1 
ATOM   8755  C C   . ASN C 1 221 ? 22.211  -0.610  -59.599  1.00 23.54  ? 214  ASN C C   1 
ATOM   8756  O O   . ASN C 1 221 ? 21.439  -0.600  -58.641  1.00 25.14  ? 214  ASN C O   1 
ATOM   8757  C CB  . ASN C 1 221 ? 22.430  1.883   -59.261  1.00 24.45  ? 214  ASN C CB  1 
ATOM   8758  C CG  . ASN C 1 221 ? 23.417  1.792   -58.111  1.00 24.04  ? 214  ASN C CG  1 
ATOM   8759  O OD1 . ASN C 1 221 ? 23.950  0.720   -57.784  1.00 21.71  ? 214  ASN C OD1 1 
ATOM   8760  N ND2 . ASN C 1 221 ? 23.651  2.929   -57.473  1.00 23.14  ? 214  ASN C ND2 1 
ATOM   8761  N N   . ILE C 1 222 ? 22.786  -1.709  -60.089  1.00 22.27  ? 215  ILE C N   1 
ATOM   8762  C CA  . ILE C 1 222 ? 22.473  -3.086  -59.606  1.00 22.97  ? 215  ILE C CA  1 
ATOM   8763  C C   . ILE C 1 222 ? 22.877  -3.212  -58.133  1.00 23.07  ? 215  ILE C C   1 
ATOM   8764  O O   . ILE C 1 222 ? 22.207  -3.971  -57.402  1.00 23.48  ? 215  ILE C O   1 
ATOM   8765  C CB  . ILE C 1 222 ? 23.147  -4.173  -60.470  1.00 23.69  ? 215  ILE C CB  1 
ATOM   8766  C CG1 . ILE C 1 222 ? 22.579  -5.564  -60.159  1.00 24.41  ? 215  ILE C CG1 1 
ATOM   8767  C CG2 . ILE C 1 222 ? 24.661  -4.147  -60.319  1.00 24.08  ? 215  ILE C CG2 1 
ATOM   8768  C CD1 . ILE C 1 222 ? 21.136  -5.758  -60.564  1.00 23.41  ? 215  ILE C CD1 1 
ATOM   8769  N N   . GLU C 1 223 ? 23.922  -2.513  -57.697  1.00 22.84  ? 216  GLU C N   1 
ATOM   8770  C CA  . GLU C 1 223 ? 24.402  -2.695  -56.310  1.00 25.50  ? 216  GLU C CA  1 
ATOM   8771  C C   . GLU C 1 223 ? 23.381  -2.084  -55.329  1.00 24.82  ? 216  GLU C C   1 
ATOM   8772  O O   . GLU C 1 223 ? 23.086  -2.751  -54.305  1.00 23.21  ? 216  GLU C O   1 
ATOM   8773  C CB  . GLU C 1 223 ? 25.836  -2.191  -56.167  1.00 28.04  ? 216  GLU C CB  1 
ATOM   8774  C CG  . GLU C 1 223 ? 26.853  -3.164  -56.746  1.00 30.77  ? 216  GLU C CG  1 
ATOM   8775  C CD  . GLU C 1 223 ? 26.679  -4.625  -56.343  1.00 32.43  ? 216  GLU C CD  1 
ATOM   8776  O OE1 . GLU C 1 223 ? 26.307  -4.885  -55.170  1.00 32.01  ? 216  GLU C OE1 1 
ATOM   8777  O OE2 . GLU C 1 223 ? 26.917  -5.501  -57.205  1.00 31.69  ? 216  GLU C OE2 1 
ATOM   8778  N N   . ALA C 1 224 ? 22.828  -0.906  -55.648  1.00 24.13  ? 217  ALA C N   1 
ATOM   8779  C CA  . ALA C 1 224 ? 21.782  -0.211  -54.849  1.00 22.87  ? 217  ALA C CA  1 
ATOM   8780  C C   . ALA C 1 224 ? 20.554  -1.111  -54.698  1.00 20.54  ? 217  ALA C C   1 
ATOM   8781  O O   . ALA C 1 224 ? 19.966  -1.175  -53.614  1.00 18.98  ? 217  ALA C O   1 
ATOM   8782  C CB  . ALA C 1 224 ? 21.404  1.085   -55.507  1.00 23.15  ? 217  ALA C CB  1 
ATOM   8783  N N   . MET C 1 225 ? 20.213  -1.814  -55.765  1.00 20.46  ? 218  MET C N   1 
ATOM   8784  C CA  . MET C 1 225 ? 19.055  -2.723  -55.802  1.00 21.61  ? 218  MET C CA  1 
ATOM   8785  C C   . MET C 1 225 ? 19.363  -3.953  -54.950  1.00 20.90  ? 218  MET C C   1 
ATOM   8786  O O   . MET C 1 225 ? 18.478  -4.358  -54.198  1.00 22.09  ? 218  MET C O   1 
ATOM   8787  C CB  . MET C 1 225 ? 18.696  -3.145  -57.234  1.00 22.83  ? 218  MET C CB  1 
ATOM   8788  C CG  . MET C 1 225 ? 17.281  -3.775  -57.325  1.00 23.11  ? 218  MET C CG  1 
ATOM   8789  S SD  . MET C 1 225 ? 16.841  -4.384  -59.007  1.00 25.72  ? 218  MET C SD  1 
ATOM   8790  C CE  . MET C 1 225 ? 16.108  -2.872  -59.642  1.00 26.17  ? 218  MET C CE  1 
ATOM   8791  N N   . ARG C 1 226 ? 20.544  -4.551  -55.086  1.00 21.33  ? 219  ARG C N   1 
ATOM   8792  C CA  . ARG C 1 226 ? 20.965  -5.706  -54.241  1.00 21.78  ? 219  ARG C CA  1 
ATOM   8793  C C   . ARG C 1 226 ? 20.794  -5.332  -52.760  1.00 21.33  ? 219  ARG C C   1 
ATOM   8794  O O   . ARG C 1 226 ? 20.166  -6.107  -51.990  1.00 19.34  ? 219  ARG C O   1 
ATOM   8795  C CB  . ARG C 1 226 ? 22.421  -6.090  -54.507  1.00 21.76  ? 219  ARG C CB  1 
ATOM   8796  C CG  . ARG C 1 226 ? 22.943  -7.156  -53.556  1.00 22.76  ? 219  ARG C CG  1 
ATOM   8797  C CD  . ARG C 1 226 ? 24.212  -7.845  -54.023  1.00 23.90  ? 219  ARG C CD  1 
ATOM   8798  N NE  . ARG C 1 226 ? 23.943  -8.772  -55.115  1.00 23.70  ? 219  ARG C NE  1 
ATOM   8799  C CZ  . ARG C 1 226 ? 23.463  -10.008 -54.979  1.00 23.83  ? 219  ARG C CZ  1 
ATOM   8800  N NH1 . ARG C 1 226 ? 23.180  -10.514 -53.785  1.00 22.59  ? 219  ARG C NH1 1 
ATOM   8801  N NH2 . ARG C 1 226 ? 23.271  -10.731 -56.068  1.00 24.66  ? 219  ARG C NH2 1 
ATOM   8802  N N   . THR C 1 227 ? 21.349  -4.180  -52.391  1.00 20.70  ? 220  THR C N   1 
ATOM   8803  C CA  . THR C 1 227 ? 21.288  -3.621  -51.017  1.00 20.03  ? 220  THR C CA  1 
ATOM   8804  C C   . THR C 1 227 ? 19.828  -3.626  -50.548  1.00 18.40  ? 220  THR C C   1 
ATOM   8805  O O   . THR C 1 227 ? 19.559  -4.136  -49.443  1.00 19.00  ? 220  THR C O   1 
ATOM   8806  C CB  . THR C 1 227 ? 21.927  -2.225  -50.976  1.00 19.86  ? 220  THR C CB  1 
ATOM   8807  O OG1 . THR C 1 227 ? 23.335  -2.382  -51.184  1.00 18.21  ? 220  THR C OG1 1 
ATOM   8808  C CG2 . THR C 1 227 ? 21.633  -1.487  -49.685  1.00 19.27  ? 220  THR C CG2 1 
ATOM   8809  N N   . ALA C 1 228 ? 18.934  -3.069  -51.358  1.00 16.95  ? 221  ALA C N   1 
ATOM   8810  C CA  . ALA C 1 228 ? 17.513  -2.864  -50.992  1.00 15.94  ? 221  ALA C CA  1 
ATOM   8811  C C   . ALA C 1 228 ? 16.860  -4.222  -50.730  1.00 15.01  ? 221  ALA C C   1 
ATOM   8812  O O   . ALA C 1 228 ? 16.144  -4.353  -49.721  1.00 14.76  ? 221  ALA C O   1 
ATOM   8813  C CB  . ALA C 1 228 ? 16.800  -2.085  -52.058  1.00 15.09  ? 221  ALA C CB  1 
ATOM   8814  N N   A LEU C 1 229 ? 17.131  -5.208  -51.592  0.46 14.61  ? 222  LEU C N   1 
ATOM   8815  N N   B LEU C 1 229 ? 17.116  -5.202  -51.597  0.54 15.15  ? 222  LEU C N   1 
ATOM   8816  C CA  A LEU C 1 229 ? 16.548  -6.573  -51.487  0.46 14.62  ? 222  LEU C CA  1 
ATOM   8817  C CA  B LEU C 1 229 ? 16.547  -6.572  -51.487  0.54 15.58  ? 222  LEU C CA  1 
ATOM   8818  C C   A LEU C 1 229 ? 17.099  -7.248  -50.239  0.46 15.01  ? 222  LEU C C   1 
ATOM   8819  C C   B LEU C 1 229 ? 17.100  -7.246  -50.241  0.54 15.53  ? 222  LEU C C   1 
ATOM   8820  O O   A LEU C 1 229 ? 16.322  -7.918  -49.524  0.46 14.41  ? 222  LEU C O   1 
ATOM   8821  O O   B LEU C 1 229 ? 16.324  -7.911  -49.525  0.54 14.75  ? 222  LEU C O   1 
ATOM   8822  C CB  A LEU C 1 229 ? 16.895  -7.395  -52.727  0.46 14.32  ? 222  LEU C CB  1 
ATOM   8823  C CB  B LEU C 1 229 ? 16.913  -7.384  -52.729  0.54 16.14  ? 222  LEU C CB  1 
ATOM   8824  C CG  A LEU C 1 229 ? 15.782  -7.485  -53.766  0.46 13.83  ? 222  LEU C CG  1 
ATOM   8825  C CG  B LEU C 1 229 ? 16.030  -7.089  -53.934  0.54 16.36  ? 222  LEU C CG  1 
ATOM   8826  C CD1 A LEU C 1 229 ? 15.424  -6.103  -54.283  0.46 13.49  ? 222  LEU C CD1 1 
ATOM   8827  C CD1 B LEU C 1 229 ? 16.781  -7.328  -55.228  0.54 17.01  ? 222  LEU C CD1 1 
ATOM   8828  C CD2 A LEU C 1 229 ? 16.174  -8.417  -54.901  0.46 13.73  ? 222  LEU C CD2 1 
ATOM   8829  C CD2 B LEU C 1 229 ? 14.772  -7.927  -53.875  0.54 16.65  ? 222  LEU C CD2 1 
ATOM   8830  N N   . ASN C 1 230 ? 18.400  -7.073  -50.014  1.00 15.74  ? 223  ASN C N   1 
ATOM   8831  C CA  . ASN C 1 230 ? 19.110  -7.708  -48.885  1.00 17.41  ? 223  ASN C CA  1 
ATOM   8832  C C   . ASN C 1 230 ? 18.600  -7.140  -47.558  1.00 17.66  ? 223  ASN C C   1 
ATOM   8833  O O   . ASN C 1 230 ? 18.332  -7.950  -46.667  1.00 17.27  ? 223  ASN C O   1 
ATOM   8834  C CB  . ASN C 1 230 ? 20.623  -7.557  -49.028  1.00 18.17  ? 223  ASN C CB  1 
ATOM   8835  C CG  . ASN C 1 230 ? 21.326  -8.619  -48.221  1.00 18.62  ? 223  ASN C CG  1 
ATOM   8836  O OD1 . ASN C 1 230 ? 20.958  -9.793  -48.274  1.00 19.06  ? 223  ASN C OD1 1 
ATOM   8837  N ND2 . ASN C 1 230 ? 22.300  -8.208  -47.436  1.00 20.33  ? 223  ASN C ND2 1 
ATOM   8838  N N   . GLU C 1 231 ? 18.493  -5.809  -47.448  1.00 19.21  ? 224  GLU C N   1 
ATOM   8839  C CA  . GLU C 1 231 ? 18.039  -5.082  -46.231  1.00 21.43  ? 224  GLU C CA  1 
ATOM   8840  C C   . GLU C 1 231 ? 16.587  -5.460  -45.944  1.00 21.16  ? 224  GLU C C   1 
ATOM   8841  O O   . GLU C 1 231 ? 16.263  -5.684  -44.769  1.00 20.26  ? 224  GLU C O   1 
ATOM   8842  C CB  . GLU C 1 231 ? 18.189  -3.564  -46.389  1.00 23.78  ? 224  GLU C CB  1 
ATOM   8843  C CG  . GLU C 1 231 ? 19.640  -3.096  -46.483  1.00 27.07  ? 224  GLU C CG  1 
ATOM   8844  C CD  . GLU C 1 231 ? 20.519  -3.268  -45.241  1.00 29.61  ? 224  GLU C CD  1 
ATOM   8845  O OE1 . GLU C 1 231 ? 20.123  -2.773  -44.131  1.00 32.55  ? 224  GLU C OE1 1 
ATOM   8846  O OE2 . GLU C 1 231 ? 21.633  -3.881  -45.374  1.00 32.82  ? 224  GLU C OE2 1 
ATOM   8847  N N   . CYS C 1 232 ? 15.757  -5.566  -46.985  1.00 19.14  ? 225  CYS C N   1 
ATOM   8848  C CA  . CYS C 1 232 ? 14.345  -5.989  -46.847  1.00 20.82  ? 225  CYS C CA  1 
ATOM   8849  C C   . CYS C 1 232 ? 14.284  -7.426  -46.305  1.00 20.84  ? 225  CYS C C   1 
ATOM   8850  O O   . CYS C 1 232 ? 13.414  -7.697  -45.449  1.00 21.55  ? 225  CYS C O   1 
ATOM   8851  C CB  . CYS C 1 232 ? 13.603  -5.813  -48.165  1.00 20.47  ? 225  CYS C CB  1 
ATOM   8852  S SG  . CYS C 1 232 ? 13.142  -4.084  -48.463  1.00 21.00  ? 225  CYS C SG  1 
ATOM   8853  N N   . LYS C 1 233 ? 15.192  -8.297  -46.748  1.00 20.35  ? 226  LYS C N   1 
ATOM   8854  C CA  . LYS C 1 233 ? 15.277  -9.706  -46.283  1.00 21.97  ? 226  LYS C CA  1 
ATOM   8855  C C   . LYS C 1 233 ? 15.687  -9.748  -44.807  1.00 22.49  ? 226  LYS C C   1 
ATOM   8856  O O   . LYS C 1 233 ? 15.058  -10.502 -44.007  1.00 22.17  ? 226  LYS C O   1 
ATOM   8857  C CB  . LYS C 1 233 ? 16.287  -10.471 -47.136  1.00 24.21  ? 226  LYS C CB  1 
ATOM   8858  C CG  . LYS C 1 233 ? 16.528  -11.909 -46.712  1.00 26.71  ? 226  LYS C CG  1 
ATOM   8859  C CD  . LYS C 1 233 ? 17.273  -12.703 -47.775  1.00 30.18  ? 226  LYS C CD  1 
ATOM   8860  C CE  . LYS C 1 233 ? 18.140  -13.821 -47.228  1.00 32.08  ? 226  LYS C CE  1 
ATOM   8861  N NZ  . LYS C 1 233 ? 17.333  -14.943 -46.681  1.00 33.84  ? 226  LYS C NZ  1 
ATOM   8862  N N   . LYS C 1 234 ? 16.705  -8.966  -44.445  1.00 22.98  ? 227  LYS C N   1 
ATOM   8863  C CA  . LYS C 1 234 ? 17.216  -8.863  -43.043  1.00 23.21  ? 227  LYS C CA  1 
ATOM   8864  C C   . LYS C 1 234 ? 16.081  -8.474  -42.078  1.00 20.42  ? 227  LYS C C   1 
ATOM   8865  O O   . LYS C 1 234 ? 16.038  -9.057  -41.002  1.00 21.81  ? 227  LYS C O   1 
ATOM   8866  C CB  . LYS C 1 234 ? 18.369  -7.853  -42.944  1.00 24.21  ? 227  LYS C CB  1 
ATOM   8867  C CG  . LYS C 1 234 ? 19.626  -8.217  -43.723  1.00 26.83  ? 227  LYS C CG  1 
ATOM   8868  C CD  . LYS C 1 234 ? 20.871  -7.536  -43.180  1.00 29.83  ? 227  LYS C CD  1 
ATOM   8869  C CE  . LYS C 1 234 ? 21.802  -6.998  -44.244  1.00 32.49  ? 227  LYS C CE  1 
ATOM   8870  N NZ  . LYS C 1 234 ? 22.934  -6.245  -43.651  1.00 35.09  ? 227  LYS C NZ  1 
ATOM   8871  N N   . THR C 1 235 ? 15.211  -7.525  -42.443  1.00 18.56  ? 228  THR C N   1 
ATOM   8872  C CA  . THR C 1 235 ? 14.222  -6.886  -41.539  1.00 17.80  ? 228  THR C CA  1 
ATOM   8873  C C   . THR C 1 235 ? 12.891  -7.620  -41.604  1.00 17.68  ? 228  THR C C   1 
ATOM   8874  O O   . THR C 1 235 ? 11.963  -7.181  -40.912  1.00 18.67  ? 228  THR C O   1 
ATOM   8875  C CB  . THR C 1 235 ? 14.050  -5.397  -41.853  1.00 17.25  ? 228  THR C CB  1 
ATOM   8876  O OG1 . THR C 1 235 ? 13.579  -5.262  -43.190  1.00 17.97  ? 228  THR C OG1 1 
ATOM   8877  C CG2 . THR C 1 235 ? 15.338  -4.624  -41.674  1.00 17.51  ? 228  THR C CG2 1 
ATOM   8878  N N   . GLY C 1 236 ? 12.802  -8.688  -42.394  1.00 18.36  ? 229  GLY C N   1 
ATOM   8879  C CA  . GLY C 1 236 ? 11.564  -9.475  -42.572  1.00 19.10  ? 229  GLY C CA  1 
ATOM   8880  C C   . GLY C 1 236 ? 10.524  -8.799  -43.460  1.00 18.95  ? 229  GLY C C   1 
ATOM   8881  O O   . GLY C 1 236 ? 9.360   -9.228  -43.374  1.00 20.56  ? 229  GLY C O   1 
ATOM   8882  N N   . ASP C 1 237 ? 10.927  -7.821  -44.293  1.00 17.62  ? 230  ASP C N   1 
ATOM   8883  C CA  . ASP C 1 237 ? 10.063  -7.060  -45.243  1.00 17.18  ? 230  ASP C CA  1 
ATOM   8884  C C   . ASP C 1 237 ? 10.424  -7.471  -46.676  1.00 16.06  ? 230  ASP C C   1 
ATOM   8885  O O   . ASP C 1 237 ? 10.639  -6.591  -47.527  1.00 14.59  ? 230  ASP C O   1 
ATOM   8886  C CB  . ASP C 1 237 ? 10.213  -5.544  -45.087  1.00 17.74  ? 230  ASP C CB  1 
ATOM   8887  C CG  . ASP C 1 237 ? 10.012  -5.035  -43.666  1.00 18.86  ? 230  ASP C CG  1 
ATOM   8888  O OD1 . ASP C 1 237 ? 8.831   -4.973  -43.224  1.00 21.05  ? 230  ASP C OD1 1 
ATOM   8889  O OD2 . ASP C 1 237 ? 11.025  -4.683  -43.007  1.00 18.53  ? 230  ASP C OD2 1 
ATOM   8890  N N   . ASP C 1 238 ? 10.460  -8.777  -46.914  1.00 15.76  ? 231  ASP C N   1 
ATOM   8891  C CA  . ASP C 1 238 ? 10.985  -9.406  -48.152  1.00 16.96  ? 231  ASP C CA  1 
ATOM   8892  C C   . ASP C 1 238 ? 10.243  -8.869  -49.381  1.00 16.27  ? 231  ASP C C   1 
ATOM   8893  O O   . ASP C 1 238 ? 9.046   -8.587  -49.318  1.00 16.79  ? 231  ASP C O   1 
ATOM   8894  C CB  . ASP C 1 238 ? 10.902  -10.930 -48.109  1.00 17.88  ? 231  ASP C CB  1 
ATOM   8895  C CG  . ASP C 1 238 ? 11.527  -11.538 -46.879  1.00 19.16  ? 231  ASP C CG  1 
ATOM   8896  O OD1 . ASP C 1 238 ? 10.858  -11.479 -45.810  1.00 23.21  ? 231  ASP C OD1 1 
ATOM   8897  O OD2 . ASP C 1 238 ? 12.700  -12.014 -46.976  1.00 21.63  ? 231  ASP C OD2 1 
ATOM   8898  N N   . VAL C 1 239 ? 10.963  -8.764  -50.485  1.00 17.12  ? 232  VAL C N   1 
ATOM   8899  C CA  . VAL C 1 239 ? 10.504  -8.090  -51.726  1.00 17.24  ? 232  VAL C CA  1 
ATOM   8900  C C   . VAL C 1 239 ? 9.710   -9.104  -52.544  1.00 16.62  ? 232  VAL C C   1 
ATOM   8901  O O   . VAL C 1 239 ? 10.248  -10.202 -52.827  1.00 16.33  ? 232  VAL C O   1 
ATOM   8902  C CB  . VAL C 1 239 ? 11.712  -7.502  -52.477  1.00 18.22  ? 232  VAL C CB  1 
ATOM   8903  C CG1 . VAL C 1 239 ? 11.367  -7.014  -53.880  1.00 18.70  ? 232  VAL C CG1 1 
ATOM   8904  C CG2 . VAL C 1 239 ? 12.354  -6.385  -51.662  1.00 17.71  ? 232  VAL C CG2 1 
ATOM   8905  N N   . ALA C 1 240 ? 8.460   -8.750  -52.873  1.00 16.84  ? 233  ALA C N   1 
ATOM   8906  C CA  . ALA C 1 240 ? 7.560   -9.547  -53.730  1.00 16.03  ? 233  ALA C CA  1 
ATOM   8907  C C   . ALA C 1 240 ? 8.015   -9.407  -55.187  1.00 16.23  ? 233  ALA C C   1 
ATOM   8908  O O   . ALA C 1 240 ? 8.053   -10.433 -55.903  1.00 17.09  ? 233  ALA C O   1 
ATOM   8909  C CB  . ALA C 1 240 ? 6.147   -9.087  -53.557  1.00 16.60  ? 233  ALA C CB  1 
ATOM   8910  N N   . ALA C 1 241 ? 8.337   -8.190  -55.627  1.00 15.33  ? 234  ALA C N   1 
ATOM   8911  C CA  . ALA C 1 241 ? 8.624   -7.918  -57.048  1.00 16.08  ? 234  ALA C CA  1 
ATOM   8912  C C   . ALA C 1 241 ? 9.508   -6.689  -57.190  1.00 16.34  ? 234  ALA C C   1 
ATOM   8913  O O   . ALA C 1 241 ? 9.411   -5.766  -56.357  1.00 17.38  ? 234  ALA C O   1 
ATOM   8914  C CB  . ALA C 1 241 ? 7.341   -7.740  -57.824  1.00 15.95  ? 234  ALA C CB  1 
ATOM   8915  N N   . VAL C 1 242 ? 10.300  -6.695  -58.249  1.00 15.76  ? 235  VAL C N   1 
ATOM   8916  C CA  . VAL C 1 242 ? 10.924  -5.480  -58.824  1.00 15.58  ? 235  VAL C CA  1 
ATOM   8917  C C   . VAL C 1 242 ? 10.155  -5.114  -60.088  1.00 14.68  ? 235  VAL C C   1 
ATOM   8918  O O   . VAL C 1 242 ? 9.926   -6.000  -60.924  1.00 14.46  ? 235  VAL C O   1 
ATOM   8919  C CB  . VAL C 1 242 ? 12.413  -5.713  -59.130  1.00 15.94  ? 235  VAL C CB  1 
ATOM   8920  C CG1 . VAL C 1 242 ? 13.058  -4.458  -59.714  1.00 15.81  ? 235  VAL C CG1 1 
ATOM   8921  C CG2 . VAL C 1 242 ? 13.154  -6.212  -57.890  1.00 15.89  ? 235  VAL C CG2 1 
ATOM   8922  N N   . ILE C 1 243 ? 9.798   -3.843  -60.223  1.00 14.46  ? 236  ILE C N   1 
ATOM   8923  C CA  . ILE C 1 243 ? 9.178   -3.289  -61.454  1.00 15.21  ? 236  ILE C CA  1 
ATOM   8924  C C   . ILE C 1 243 ? 10.098  -2.196  -61.986  1.00 15.56  ? 236  ILE C C   1 
ATOM   8925  O O   . ILE C 1 243 ? 10.494  -1.359  -61.199  1.00 14.61  ? 236  ILE C O   1 
ATOM   8926  C CB  . ILE C 1 243 ? 7.751   -2.764  -61.190  1.00 14.96  ? 236  ILE C CB  1 
ATOM   8927  C CG1 . ILE C 1 243 ? 7.109   -2.254  -62.478  1.00 15.26  ? 236  ILE C CG1 1 
ATOM   8928  C CG2 . ILE C 1 243 ? 7.743   -1.689  -60.124  1.00 14.90  ? 236  ILE C CG2 1 
ATOM   8929  C CD1 . ILE C 1 243 ? 5.657   -1.870  -62.330  1.00 15.07  ? 236  ILE C CD1 1 
ATOM   8930  N N   . LEU C 1 244 ? 10.359  -2.195  -63.294  1.00 17.64  ? 237  LEU C N   1 
ATOM   8931  C CA  . LEU C 1 244 ? 11.178  -1.160  -63.972  1.00 19.14  ? 237  LEU C CA  1 
ATOM   8932  C C   . LEU C 1 244 ? 10.842  -1.126  -65.462  1.00 19.84  ? 237  LEU C C   1 
ATOM   8933  O O   . LEU C 1 244 ? 10.387  -2.143  -66.011  1.00 19.42  ? 237  LEU C O   1 
ATOM   8934  C CB  . LEU C 1 244 ? 12.681  -1.413  -63.728  1.00 20.63  ? 237  LEU C CB  1 
ATOM   8935  C CG  . LEU C 1 244 ? 13.305  -2.655  -64.372  1.00 20.29  ? 237  LEU C CG  1 
ATOM   8936  C CD1 . LEU C 1 244 ? 14.800  -2.649  -64.205  1.00 21.26  ? 237  LEU C CD1 1 
ATOM   8937  C CD2 . LEU C 1 244 ? 12.717  -3.943  -63.820  1.00 21.17  ? 237  LEU C CD2 1 
ATOM   8938  N N   . GLU C 1 245 ? 11.036  0.043   -66.063  1.00 20.59  ? 238  GLU C N   1 
ATOM   8939  C CA  . GLU C 1 245 ? 11.075  0.212   -67.528  1.00 21.01  ? 238  GLU C CA  1 
ATOM   8940  C C   . GLU C 1 245 ? 12.452  -0.226  -67.992  1.00 21.20  ? 238  GLU C C   1 
ATOM   8941  O O   . GLU C 1 245 ? 13.440  0.108   -67.349  1.00 21.44  ? 238  GLU C O   1 
ATOM   8942  C CB  . GLU C 1 245 ? 10.866  1.672   -67.922  1.00 22.82  ? 238  GLU C CB  1 
ATOM   8943  C CG  . GLU C 1 245 ? 9.583   2.308   -67.361  1.00 22.47  ? 238  GLU C CG  1 
ATOM   8944  C CD  . GLU C 1 245 ? 9.631   3.827   -67.317  1.00 21.90  ? 238  GLU C CD  1 
ATOM   8945  O OE1 . GLU C 1 245 ? 9.405   4.480   -68.378  1.00 18.53  ? 238  GLU C OE1 1 
ATOM   8946  O OE2 . GLU C 1 245 ? 9.988   4.346   -66.243  1.00 21.97  ? 238  GLU C OE2 1 
ATOM   8947  N N   . PRO C 1 246 ? 12.582  -0.968  -69.113  1.00 19.40  ? 239  PRO C N   1 
ATOM   8948  C CA  . PRO C 1 246 ? 13.900  -1.330  -69.632  1.00 17.98  ? 239  PRO C CA  1 
ATOM   8949  C C   . PRO C 1 246 ? 14.733  -0.092  -69.989  1.00 17.53  ? 239  PRO C C   1 
ATOM   8950  O O   . PRO C 1 246 ? 15.947  -0.163  -69.955  1.00 19.65  ? 239  PRO C O   1 
ATOM   8951  C CB  . PRO C 1 246 ? 13.612  -2.119  -70.912  1.00 18.59  ? 239  PRO C CB  1 
ATOM   8952  C CG  . PRO C 1 246 ? 12.156  -2.511  -70.809  1.00 19.47  ? 239  PRO C CG  1 
ATOM   8953  C CD  . PRO C 1 246 ? 11.483  -1.480  -69.932  1.00 18.86  ? 239  PRO C CD  1 
ATOM   8954  N N   . ILE C 1 247 ? 14.055  0.975   -70.389  1.00 17.15  ? 240  ILE C N   1 
ATOM   8955  C CA  . ILE C 1 247 ? 14.577  2.338   -70.692  1.00 18.28  ? 240  ILE C CA  1 
ATOM   8956  C C   . ILE C 1 247 ? 13.496  3.288   -70.200  1.00 19.24  ? 240  ILE C C   1 
ATOM   8957  O O   . ILE C 1 247 ? 12.308  3.066   -70.516  1.00 20.86  ? 240  ILE C O   1 
ATOM   8958  C CB  . ILE C 1 247 ? 14.832  2.536   -72.205  1.00 20.35  ? 240  ILE C CB  1 
ATOM   8959  C CG1 . ILE C 1 247 ? 15.842  1.519   -72.740  1.00 22.06  ? 240  ILE C CG1 1 
ATOM   8960  C CG2 . ILE C 1 247 ? 15.241  3.974   -72.521  1.00 20.10  ? 240  ILE C CG2 1 
ATOM   8961  C CD1 . ILE C 1 247 ? 15.794  1.334   -74.235  1.00 23.89  ? 240  ILE C CD1 1 
ATOM   8962  N N   . GLN C 1 248 ? 13.862  4.278   -69.410  1.00 20.30  ? 241  GLN C N   1 
ATOM   8963  C CA  . GLN C 1 248 ? 12.872  5.181   -68.788  1.00 21.88  ? 241  GLN C CA  1 
ATOM   8964  C C   . GLN C 1 248 ? 12.491  6.202   -69.850  1.00 22.55  ? 241  GLN C C   1 
ATOM   8965  O O   . GLN C 1 248 ? 13.395  6.853   -70.367  1.00 22.06  ? 241  GLN C O   1 
ATOM   8966  C CB  . GLN C 1 248 ? 13.437  5.770   -67.504  1.00 23.98  ? 241  GLN C CB  1 
ATOM   8967  C CG  . GLN C 1 248 ? 13.679  4.704   -66.438  1.00 24.86  ? 241  GLN C CG  1 
ATOM   8968  C CD  . GLN C 1 248 ? 14.054  5.322   -65.114  1.00 25.77  ? 241  GLN C CD  1 
ATOM   8969  O OE1 . GLN C 1 248 ? 14.684  6.376   -65.048  1.00 25.51  ? 241  GLN C OE1 1 
ATOM   8970  N NE2 . GLN C 1 248 ? 13.659  4.665   -64.036  1.00 27.12  ? 241  GLN C NE2 1 
ATOM   8971  N N   . GLY C 1 249 ? 11.210  6.236   -70.209  1.00 22.67  ? 242  GLY C N   1 
ATOM   8972  C CA  . GLY C 1 249 ? 10.641  7.216   -71.143  1.00 23.75  ? 242  GLY C CA  1 
ATOM   8973  C C   . GLY C 1 249 ? 10.489  8.566   -70.480  1.00 24.55  ? 242  GLY C C   1 
ATOM   8974  O O   . GLY C 1 249 ? 11.230  9.493   -70.826  1.00 23.24  ? 242  GLY C O   1 
ATOM   8975  N N   . GLU C 1 250 ? 9.566   8.679   -69.532  1.00 27.69  ? 243  GLU C N   1 
ATOM   8976  C CA  . GLU C 1 250 ? 9.210   9.987   -68.914  1.00 31.50  ? 243  GLU C CA  1 
ATOM   8977  C C   . GLU C 1 250 ? 10.426  10.498  -68.128  1.00 29.65  ? 243  GLU C C   1 
ATOM   8978  O O   . GLU C 1 250 ? 10.557  11.730  -67.978  1.00 28.32  ? 243  GLU C O   1 
ATOM   8979  C CB  . GLU C 1 250 ? 7.938   9.850   -68.071  1.00 34.43  ? 243  GLU C CB  1 
ATOM   8980  C CG  . GLU C 1 250 ? 6.733   9.316   -68.856  1.00 37.77  ? 243  GLU C CG  1 
ATOM   8981  C CD  . GLU C 1 250 ? 6.372   9.987   -70.186  1.00 42.20  ? 243  GLU C CD  1 
ATOM   8982  O OE1 . GLU C 1 250 ? 6.551   11.220  -70.305  1.00 43.78  ? 243  GLU C OE1 1 
ATOM   8983  O OE2 . GLU C 1 250 ? 5.899   9.278   -71.122  1.00 41.25  ? 243  GLU C OE2 1 
ATOM   8984  N N   . GLY C 1 251 ? 11.293  9.571   -67.704  1.00 28.26  ? 244  GLY C N   1 
ATOM   8985  C CA  . GLY C 1 251 ? 12.595  9.837   -67.063  1.00 29.12  ? 244  GLY C CA  1 
ATOM   8986  C C   . GLY C 1 251 ? 13.532  10.636  -67.953  1.00 29.43  ? 244  GLY C C   1 
ATOM   8987  O O   . GLY C 1 251 ? 14.486  11.202  -67.393  1.00 30.59  ? 244  GLY C O   1 
ATOM   8988  N N   . GLY C 1 252 ? 13.285  10.667  -69.278  1.00 27.88  ? 245  GLY C N   1 
ATOM   8989  C CA  . GLY C 1 252 ? 14.030  11.451  -70.288  1.00 25.71  ? 245  GLY C CA  1 
ATOM   8990  C C   . GLY C 1 252 ? 14.892  10.572  -71.188  1.00 26.69  ? 245  GLY C C   1 
ATOM   8991  O O   . GLY C 1 252 ? 15.967  11.036  -71.606  1.00 28.06  ? 245  GLY C O   1 
ATOM   8992  N N   . VAL C 1 253 ? 14.424  9.364   -71.520  1.00 27.00  ? 246  VAL C N   1 
ATOM   8993  C CA  . VAL C 1 253 ? 15.155  8.323   -72.309  1.00 27.31  ? 246  VAL C CA  1 
ATOM   8994  C C   . VAL C 1 253 ? 16.460  7.979   -71.595  1.00 26.17  ? 246  VAL C C   1 
ATOM   8995  O O   . VAL C 1 253 ? 17.533  8.372   -72.045  1.00 27.00  ? 246  VAL C O   1 
ATOM   8996  C CB  . VAL C 1 253 ? 15.374  8.753   -73.766  1.00 28.84  ? 246  VAL C CB  1 
ATOM   8997  C CG1 . VAL C 1 253 ? 16.065  7.652   -74.572  1.00 27.22  ? 246  VAL C CG1 1 
ATOM   8998  C CG2 . VAL C 1 253 ? 14.043  9.179   -74.397  1.00 29.27  ? 246  VAL C CG2 1 
ATOM   8999  N N   . ILE C 1 254 ? 16.330  7.305   -70.467  1.00 26.98  ? 247  ILE C N   1 
ATOM   9000  C CA  . ILE C 1 254 ? 17.465  6.922   -69.591  1.00 25.83  ? 247  ILE C CA  1 
ATOM   9001  C C   . ILE C 1 254 ? 17.785  5.478   -69.923  1.00 26.55  ? 247  ILE C C   1 
ATOM   9002  O O   . ILE C 1 254 ? 16.963  4.598   -69.638  1.00 25.33  ? 247  ILE C O   1 
ATOM   9003  C CB  . ILE C 1 254 ? 17.133  7.093   -68.102  1.00 26.08  ? 247  ILE C CB  1 
ATOM   9004  C CG1 . ILE C 1 254 ? 16.621  8.497   -67.778  1.00 26.86  ? 247  ILE C CG1 1 
ATOM   9005  C CG2 . ILE C 1 254 ? 18.345  6.737   -67.268  1.00 25.61  ? 247  ILE C CG2 1 
ATOM   9006  C CD1 . ILE C 1 254 ? 17.492  9.608   -68.327  1.00 27.87  ? 247  ILE C CD1 1 
ATOM   9007  N N   . LEU C 1 255 ? 18.933  5.275   -70.543  1.00 28.78  ? 248  LEU C N   1 
ATOM   9008  C CA  . LEU C 1 255 ? 19.422  3.933   -70.926  1.00 29.32  ? 248  LEU C CA  1 
ATOM   9009  C C   . LEU C 1 255 ? 20.211  3.366   -69.756  1.00 26.24  ? 248  LEU C C   1 
ATOM   9010  O O   . LEU C 1 255 ? 21.097  4.017   -69.207  1.00 26.22  ? 248  LEU C O   1 
ATOM   9011  C CB  . LEU C 1 255 ? 20.264  4.034   -72.203  1.00 31.53  ? 248  LEU C CB  1 
ATOM   9012  C CG  . LEU C 1 255 ? 19.472  3.921   -73.505  1.00 30.56  ? 248  LEU C CG  1 
ATOM   9013  C CD1 . LEU C 1 255 ? 18.537  5.106   -73.661  1.00 32.03  ? 248  LEU C CD1 1 
ATOM   9014  C CD2 . LEU C 1 255 ? 20.402  3.807   -74.701  1.00 31.33  ? 248  LEU C CD2 1 
ATOM   9015  N N   . PRO C 1 256 ? 19.896  2.124   -69.354  1.00 23.74  ? 249  PRO C N   1 
ATOM   9016  C CA  . PRO C 1 256 ? 20.651  1.460   -68.296  1.00 24.07  ? 249  PRO C CA  1 
ATOM   9017  C C   . PRO C 1 256 ? 22.029  1.064   -68.805  1.00 24.74  ? 249  PRO C C   1 
ATOM   9018  O O   . PRO C 1 256 ? 22.228  0.954   -70.009  1.00 20.80  ? 249  PRO C O   1 
ATOM   9019  C CB  . PRO C 1 256 ? 19.813  0.214   -68.012  1.00 23.37  ? 249  PRO C CB  1 
ATOM   9020  C CG  . PRO C 1 256 ? 19.178  -0.090  -69.361  1.00 23.77  ? 249  PRO C CG  1 
ATOM   9021  C CD  . PRO C 1 256 ? 18.856  1.270   -69.946  1.00 23.05  ? 249  PRO C CD  1 
ATOM   9022  N N   . PRO C 1 257 ? 23.019  0.813   -67.919  1.00 26.55  ? 250  PRO C N   1 
ATOM   9023  C CA  . PRO C 1 257 ? 24.318  0.327   -68.357  1.00 27.37  ? 250  PRO C CA  1 
ATOM   9024  C C   . PRO C 1 257 ? 24.087  -1.052  -68.953  1.00 27.34  ? 250  PRO C C   1 
ATOM   9025  O O   . PRO C 1 257 ? 23.166  -1.765  -68.573  1.00 26.89  ? 250  PRO C O   1 
ATOM   9026  C CB  . PRO C 1 257 ? 25.191  0.275   -67.093  1.00 28.09  ? 250  PRO C CB  1 
ATOM   9027  C CG  . PRO C 1 257 ? 24.414  1.047   -66.058  1.00 28.99  ? 250  PRO C CG  1 
ATOM   9028  C CD  . PRO C 1 257 ? 22.952  0.942   -66.465  1.00 28.68  ? 250  PRO C CD  1 
ATOM   9029  N N   . PRO C 1 258 ? 24.916  -1.464  -69.922  1.00 28.61  ? 251  PRO C N   1 
ATOM   9030  C CA  . PRO C 1 258 ? 24.698  -2.756  -70.580  1.00 28.08  ? 251  PRO C CA  1 
ATOM   9031  C C   . PRO C 1 258 ? 24.780  -3.910  -69.561  1.00 25.79  ? 251  PRO C C   1 
ATOM   9032  O O   . PRO C 1 258 ? 25.586  -3.822  -68.633  1.00 24.39  ? 251  PRO C O   1 
ATOM   9033  C CB  . PRO C 1 258 ? 25.811  -2.782  -71.652  1.00 28.64  ? 251  PRO C CB  1 
ATOM   9034  C CG  . PRO C 1 258 ? 26.869  -1.790  -71.156  1.00 27.82  ? 251  PRO C CG  1 
ATOM   9035  C CD  . PRO C 1 258 ? 26.107  -0.730  -70.395  1.00 28.24  ? 251  PRO C CD  1 
ATOM   9036  N N   . GLY C 1 259 ? 23.929  -4.931  -69.722  1.00 24.11  ? 252  GLY C N   1 
ATOM   9037  C CA  . GLY C 1 259 ? 23.876  -6.119  -68.842  1.00 25.21  ? 252  GLY C CA  1 
ATOM   9038  C C   . GLY C 1 259 ? 23.022  -5.922  -67.587  1.00 24.68  ? 252  GLY C C   1 
ATOM   9039  O O   . GLY C 1 259 ? 22.760  -6.935  -66.896  1.00 23.42  ? 252  GLY C O   1 
ATOM   9040  N N   . TYR C 1 260 ? 22.616  -4.677  -67.286  1.00 24.34  ? 253  TYR C N   1 
ATOM   9041  C CA  . TYR C 1 260 ? 21.791  -4.276  -66.111  1.00 23.06  ? 253  TYR C CA  1 
ATOM   9042  C C   . TYR C 1 260 ? 20.529  -5.131  -66.005  1.00 20.70  ? 253  TYR C C   1 
ATOM   9043  O O   . TYR C 1 260 ? 20.236  -5.705  -64.954  1.00 19.92  ? 253  TYR C O   1 
ATOM   9044  C CB  . TYR C 1 260 ? 21.337  -2.821  -66.242  1.00 22.80  ? 253  TYR C CB  1 
ATOM   9045  C CG  . TYR C 1 260 ? 20.414  -2.355  -65.149  1.00 21.65  ? 253  TYR C CG  1 
ATOM   9046  C CD1 . TYR C 1 260 ? 20.827  -2.324  -63.819  1.00 21.96  ? 253  TYR C CD1 1 
ATOM   9047  C CD2 . TYR C 1 260 ? 19.127  -1.936  -65.434  1.00 21.09  ? 253  TYR C CD2 1 
ATOM   9048  C CE1 . TYR C 1 260 ? 19.979  -1.895  -62.811  1.00 20.12  ? 253  TYR C CE1 1 
ATOM   9049  C CE2 . TYR C 1 260 ? 18.270  -1.503  -64.434  1.00 20.31  ? 253  TYR C CE2 1 
ATOM   9050  C CZ  . TYR C 1 260 ? 18.698  -1.481  -63.126  1.00 19.29  ? 253  TYR C CZ  1 
ATOM   9051  O OH  . TYR C 1 260 ? 17.855  -1.019  -62.173  1.00 20.30  ? 253  TYR C OH  1 
ATOM   9052  N N   . LEU C 1 261 ? 19.768  -5.173  -67.085  1.00 19.83  ? 254  LEU C N   1 
ATOM   9053  C CA  . LEU C 1 261 ? 18.482  -5.915  -67.117  1.00 20.08  ? 254  LEU C CA  1 
ATOM   9054  C C   . LEU C 1 261 ? 18.741  -7.399  -66.785  1.00 19.73  ? 254  LEU C C   1 
ATOM   9055  O O   . LEU C 1 261 ? 17.979  -8.003  -66.006  1.00 19.95  ? 254  LEU C O   1 
ATOM   9056  C CB  . LEU C 1 261 ? 17.881  -5.714  -68.507  1.00 20.13  ? 254  LEU C CB  1 
ATOM   9057  C CG  . LEU C 1 261 ? 16.418  -5.289  -68.555  1.00 20.99  ? 254  LEU C CG  1 
ATOM   9058  C CD1 . LEU C 1 261 ? 16.138  -4.132  -67.607  1.00 22.69  ? 254  LEU C CD1 1 
ATOM   9059  C CD2 . LEU C 1 261 ? 16.012  -4.916  -69.965  1.00 19.56  ? 254  LEU C CD2 1 
ATOM   9060  N N   . THR C 1 262 ? 19.806  -7.971  -67.341  1.00 18.64  ? 255  THR C N   1 
ATOM   9061  C CA  . THR C 1 262 ? 20.171  -9.392  -67.160  1.00 18.00  ? 255  THR C CA  1 
ATOM   9062  C C   . THR C 1 262 ? 20.491  -9.624  -65.695  1.00 18.11  ? 255  THR C C   1 
ATOM   9063  O O   . THR C 1 262 ? 20.107  -10.674 -65.159  1.00 20.68  ? 255  THR C O   1 
ATOM   9064  C CB  . THR C 1 262 ? 21.358  -9.751  -68.048  1.00 18.77  ? 255  THR C CB  1 
ATOM   9065  O OG1 . THR C 1 262 ? 20.896  -9.685  -69.409  1.00 18.25  ? 255  THR C OG1 1 
ATOM   9066  C CG2 . THR C 1 262 ? 21.938  -11.102 -67.698  1.00 19.20  ? 255  THR C CG2 1 
ATOM   9067  N N   . ALA C 1 263 ? 21.176  -8.665  -65.082  1.00 18.11  ? 256  ALA C N   1 
ATOM   9068  C CA  . ALA C 1 263 ? 21.610  -8.708  -63.660  1.00 18.33  ? 256  ALA C CA  1 
ATOM   9069  C C   . ALA C 1 263 ? 20.374  -8.613  -62.757  1.00 16.26  ? 256  ALA C C   1 
ATOM   9070  O O   . ALA C 1 263 ? 20.282  -9.375  -61.790  1.00 15.67  ? 256  ALA C O   1 
ATOM   9071  C CB  . ALA C 1 263 ? 22.630  -7.614  -63.374  1.00 17.70  ? 256  ALA C CB  1 
ATOM   9072  N N   . VAL C 1 264 ? 19.450  -7.715  -63.074  1.00 16.28  ? 257  VAL C N   1 
ATOM   9073  C CA  . VAL C 1 264 ? 18.168  -7.546  -62.318  1.00 16.75  ? 257  VAL C CA  1 
ATOM   9074  C C   . VAL C 1 264 ? 17.417  -8.884  -62.325  1.00 17.23  ? 257  VAL C C   1 
ATOM   9075  O O   . VAL C 1 264 ? 16.871  -9.255  -61.263  1.00 17.35  ? 257  VAL C O   1 
ATOM   9076  C CB  . VAL C 1 264 ? 17.312  -6.400  -62.887  1.00 15.91  ? 257  VAL C CB  1 
ATOM   9077  C CG1 . VAL C 1 264 ? 15.919  -6.396  -62.299  1.00 15.54  ? 257  VAL C CG1 1 
ATOM   9078  C CG2 . VAL C 1 264 ? 17.973  -5.047  -62.690  1.00 15.63  ? 257  VAL C CG2 1 
ATOM   9079  N N   . ARG C 1 265 ? 17.426  -9.588  -63.464  1.00 18.24  ? 258  ARG C N   1 
ATOM   9080  C CA  . ARG C 1 265 ? 16.767  -10.909 -63.617  1.00 19.54  ? 258  ARG C CA  1 
ATOM   9081  C C   . ARG C 1 265 ? 17.431  -11.927 -62.679  1.00 20.17  ? 258  ARG C C   1 
ATOM   9082  O O   . ARG C 1 265 ? 16.708  -12.632 -61.974  1.00 19.00  ? 258  ARG C O   1 
ATOM   9083  C CB  . ARG C 1 265 ? 16.787  -11.364 -65.082  1.00 19.94  ? 258  ARG C CB  1 
ATOM   9084  C CG  . ARG C 1 265 ? 16.465  -12.843 -65.299  1.00 20.59  ? 258  ARG C CG  1 
ATOM   9085  C CD  . ARG C 1 265 ? 14.999  -13.242 -65.214  1.00 22.46  ? 258  ARG C CD  1 
ATOM   9086  N NE  . ARG C 1 265 ? 14.427  -13.320 -63.875  1.00 23.59  ? 258  ARG C NE  1 
ATOM   9087  C CZ  . ARG C 1 265 ? 13.121  -13.397 -63.605  1.00 24.43  ? 258  ARG C CZ  1 
ATOM   9088  N NH1 . ARG C 1 265 ? 12.236  -13.408 -64.586  1.00 24.85  ? 258  ARG C NH1 1 
ATOM   9089  N NH2 . ARG C 1 265 ? 12.697  -13.460 -62.353  1.00 24.65  ? 258  ARG C NH2 1 
ATOM   9090  N N   . LYS C 1 266 ? 18.761  -12.027 -62.691  1.00 22.84  ? 259  LYS C N   1 
ATOM   9091  C CA  . LYS C 1 266 ? 19.485  -12.967 -61.793  1.00 24.37  ? 259  LYS C CA  1 
ATOM   9092  C C   . LYS C 1 266 ? 19.230  -12.587 -60.330  1.00 25.17  ? 259  LYS C C   1 
ATOM   9093  O O   . LYS C 1 266 ? 19.066  -13.496 -59.489  1.00 24.11  ? 259  LYS C O   1 
ATOM   9094  C CB  . LYS C 1 266 ? 20.990  -12.959 -62.061  1.00 24.73  ? 259  LYS C CB  1 
ATOM   9095  C CG  . LYS C 1 266 ? 21.414  -13.560 -63.385  1.00 27.82  ? 259  LYS C CG  1 
ATOM   9096  C CD  . LYS C 1 266 ? 22.512  -14.611 -63.244  1.00 30.44  ? 259  LYS C CD  1 
ATOM   9097  C CE  . LYS C 1 266 ? 23.710  -14.388 -64.143  1.00 30.31  ? 259  LYS C CE  1 
ATOM   9098  N NZ  . LYS C 1 266 ? 23.308  -14.070 -65.530  1.00 31.15  ? 259  LYS C NZ  1 
ATOM   9099  N N   . LEU C 1 267 ? 19.227  -11.287 -60.038  1.00 25.71  ? 260  LEU C N   1 
ATOM   9100  C CA  . LEU C 1 267 ? 19.032  -10.731 -58.679  1.00 25.37  ? 260  LEU C CA  1 
ATOM   9101  C C   . LEU C 1 267 ? 17.633  -11.110 -58.185  1.00 24.60  ? 260  LEU C C   1 
ATOM   9102  O O   . LEU C 1 267 ? 17.528  -11.645 -57.068  1.00 23.01  ? 260  LEU C O   1 
ATOM   9103  C CB  . LEU C 1 267 ? 19.210  -9.216  -58.751  1.00 27.33  ? 260  LEU C CB  1 
ATOM   9104  C CG  . LEU C 1 267 ? 19.299  -8.510  -57.405  1.00 30.22  ? 260  LEU C CG  1 
ATOM   9105  C CD1 . LEU C 1 267 ? 20.672  -8.727  -56.784  1.00 33.34  ? 260  LEU C CD1 1 
ATOM   9106  C CD2 . LEU C 1 267 ? 19.035  -7.032  -57.563  1.00 30.67  ? 260  LEU C CD2 1 
ATOM   9107  N N   . CYS C 1 268 ? 16.605  -10.890 -59.004  1.00 24.76  ? 261  CYS C N   1 
ATOM   9108  C CA  . CYS C 1 268 ? 15.212  -11.346 -58.724  1.00 25.11  ? 261  CYS C CA  1 
ATOM   9109  C C   . CYS C 1 268 ? 15.190  -12.866 -58.518  1.00 24.32  ? 261  CYS C C   1 
ATOM   9110  O O   . CYS C 1 268 ? 14.573  -13.318 -57.561  1.00 25.20  ? 261  CYS C O   1 
ATOM   9111  C CB  . CYS C 1 268 ? 14.251  -10.926 -59.828  1.00 24.91  ? 261  CYS C CB  1 
ATOM   9112  S SG  . CYS C 1 268 ? 13.837  -9.167  -59.759  1.00 26.26  ? 261  CYS C SG  1 
ATOM   9113  N N   . ASP C 1 269 ? 15.848  -13.631 -59.380  1.00 25.74  ? 262  ASP C N   1 
ATOM   9114  C CA  . ASP C 1 269 ? 15.886  -15.112 -59.268  1.00 26.87  ? 262  ASP C CA  1 
ATOM   9115  C C   . ASP C 1 269 ? 16.472  -15.517 -57.915  1.00 26.20  ? 262  ASP C C   1 
ATOM   9116  O O   . ASP C 1 269 ? 15.988  -16.485 -57.327  1.00 27.66  ? 262  ASP C O   1 
ATOM   9117  C CB  . ASP C 1 269 ? 16.716  -15.737 -60.389  1.00 28.47  ? 262  ASP C CB  1 
ATOM   9118  C CG  . ASP C 1 269 ? 15.981  -15.784 -61.715  1.00 29.24  ? 262  ASP C CG  1 
ATOM   9119  O OD1 . ASP C 1 269 ? 14.725  -15.765 -61.681  1.00 29.82  ? 262  ASP C OD1 1 
ATOM   9120  O OD2 . ASP C 1 269 ? 16.676  -15.838 -62.759  1.00 27.58  ? 262  ASP C OD2 1 
ATOM   9121  N N   . GLU C 1 270 ? 17.504  -14.815 -57.465  1.00 26.28  ? 263  GLU C N   1 
ATOM   9122  C CA  . GLU C 1 270 ? 18.277  -15.169 -56.251  1.00 28.70  ? 263  GLU C CA  1 
ATOM   9123  C C   . GLU C 1 270 ? 17.418  -14.955 -54.997  1.00 26.38  ? 263  GLU C C   1 
ATOM   9124  O O   . GLU C 1 270 ? 17.419  -15.844 -54.132  1.00 27.38  ? 263  GLU C O   1 
ATOM   9125  C CB  . GLU C 1 270 ? 19.575  -14.352 -56.208  1.00 30.44  ? 263  GLU C CB  1 
ATOM   9126  C CG  . GLU C 1 270 ? 20.343  -14.521 -54.917  1.00 32.04  ? 263  GLU C CG  1 
ATOM   9127  C CD  . GLU C 1 270 ? 21.648  -13.756 -54.856  1.00 34.95  ? 263  GLU C CD  1 
ATOM   9128  O OE1 . GLU C 1 270 ? 22.260  -13.585 -55.926  1.00 36.78  ? 263  GLU C OE1 1 
ATOM   9129  O OE2 . GLU C 1 270 ? 22.052  -13.341 -53.728  1.00 38.34  ? 263  GLU C OE2 1 
ATOM   9130  N N   . PHE C 1 271 ? 16.723  -13.821 -54.906  1.00 24.91  ? 264  PHE C N   1 
ATOM   9131  C CA  . PHE C 1 271 ? 15.920  -13.400 -53.723  1.00 24.24  ? 264  PHE C CA  1 
ATOM   9132  C C   . PHE C 1 271 ? 14.484  -13.950 -53.785  1.00 24.25  ? 264  PHE C C   1 
ATOM   9133  O O   . PHE C 1 271 ? 13.727  -13.728 -52.813  1.00 25.44  ? 264  PHE C O   1 
ATOM   9134  C CB  . PHE C 1 271 ? 15.923  -11.876 -53.599  1.00 22.86  ? 264  PHE C CB  1 
ATOM   9135  C CG  . PHE C 1 271 ? 17.185  -11.338 -52.992  1.00 21.93  ? 264  PHE C CG  1 
ATOM   9136  C CD1 . PHE C 1 271 ? 18.302  -11.103 -53.768  1.00 22.13  ? 264  PHE C CD1 1 
ATOM   9137  C CD2 . PHE C 1 271 ? 17.270  -11.109 -51.632  1.00 22.21  ? 264  PHE C CD2 1 
ATOM   9138  C CE1 . PHE C 1 271 ? 19.473  -10.619 -53.197  1.00 23.33  ? 264  PHE C CE1 1 
ATOM   9139  C CE2 . PHE C 1 271 ? 18.443  -10.636 -51.060  1.00 22.95  ? 264  PHE C CE2 1 
ATOM   9140  C CZ  . PHE C 1 271 ? 19.550  -10.403 -51.840  1.00 23.12  ? 264  PHE C CZ  1 
ATOM   9141  N N   . GLY C 1 272 ? 14.114  -14.640 -54.874  1.00 24.74  ? 265  GLY C N   1 
ATOM   9142  C CA  . GLY C 1 272 ? 12.750  -15.161 -55.113  1.00 25.04  ? 265  GLY C CA  1 
ATOM   9143  C C   . GLY C 1 272 ? 11.714  -14.050 -55.298  1.00 24.01  ? 265  GLY C C   1 
ATOM   9144  O O   . GLY C 1 272 ? 10.561  -14.266 -54.924  1.00 21.70  ? 265  GLY C O   1 
ATOM   9145  N N   . ALA C 1 273 ? 12.110  -12.905 -55.870  1.00 23.90  ? 266  ALA C N   1 
ATOM   9146  C CA  . ALA C 1 273 ? 11.227  -11.774 -56.254  1.00 22.05  ? 266  ALA C CA  1 
ATOM   9147  C C   . ALA C 1 273 ? 10.791  -11.934 -57.711  1.00 20.07  ? 266  ALA C C   1 
ATOM   9148  O O   . ALA C 1 273 ? 11.585  -12.467 -58.519  1.00 21.05  ? 266  ALA C O   1 
ATOM   9149  C CB  . ALA C 1 273 ? 11.926  -10.449 -56.053  1.00 22.17  ? 266  ALA C CB  1 
ATOM   9150  N N   . LEU C 1 274 ? 9.579   -11.487 -58.045  1.00 18.34  ? 267  LEU C N   1 
ATOM   9151  C CA  . LEU C 1 274 ? 9.096   -11.490 -59.450  1.00 17.85  ? 267  LEU C CA  1 
ATOM   9152  C C   . LEU C 1 274 ? 9.644   -10.260 -60.163  1.00 16.58  ? 267  LEU C C   1 
ATOM   9153  O O   . LEU C 1 274 ? 9.716   -9.179  -59.565  1.00 15.22  ? 267  LEU C O   1 
ATOM   9154  C CB  . LEU C 1 274 ? 7.566   -11.528 -59.507  1.00 18.52  ? 267  LEU C CB  1 
ATOM   9155  C CG  . LEU C 1 274 ? 6.912   -12.767 -58.889  1.00 19.03  ? 267  LEU C CG  1 
ATOM   9156  C CD1 . LEU C 1 274 ? 5.409   -12.726 -59.023  1.00 18.71  ? 267  LEU C CD1 1 
ATOM   9157  C CD2 . LEU C 1 274 ? 7.425   -14.044 -59.519  1.00 19.92  ? 267  LEU C CD2 1 
ATOM   9158  N N   . MET C 1 275 ? 10.032  -10.445 -61.411  1.00 17.68  ? 268  MET C N   1 
ATOM   9159  C CA  . MET C 1 275 ? 10.523  -9.356  -62.278  1.00 18.19  ? 268  MET C CA  1 
ATOM   9160  C C   . MET C 1 275 ? 9.380   -8.850  -63.159  1.00 16.56  ? 268  MET C C   1 
ATOM   9161  O O   . MET C 1 275 ? 8.832   -9.634  -63.970  1.00 15.45  ? 268  MET C O   1 
ATOM   9162  C CB  . MET C 1 275 ? 11.680  -9.847  -63.141  1.00 20.57  ? 268  MET C CB  1 
ATOM   9163  C CG  . MET C 1 275 ? 12.233  -8.742  -64.007  1.00 22.95  ? 268  MET C CG  1 
ATOM   9164  S SD  . MET C 1 275 ? 13.762  -9.192  -64.789  1.00 24.04  ? 268  MET C SD  1 
ATOM   9165  C CE  . MET C 1 275 ? 14.113  -7.654  -65.643  1.00 25.38  ? 268  MET C CE  1 
ATOM   9166  N N   . ILE C 1 276 ? 9.009   -7.589  -62.968  1.00 16.45  ? 269  ILE C N   1 
ATOM   9167  C CA  . ILE C 1 276 ? 7.966   -6.914  -63.785  1.00 18.10  ? 269  ILE C CA  1 
ATOM   9168  C C   . ILE C 1 276 ? 8.653   -5.917  -64.711  1.00 18.76  ? 269  ILE C C   1 
ATOM   9169  O O   . ILE C 1 276 ? 9.262   -4.965  -64.196  1.00 18.78  ? 269  ILE C O   1 
ATOM   9170  C CB  . ILE C 1 276 ? 6.922   -6.214  -62.903  1.00 18.21  ? 269  ILE C CB  1 
ATOM   9171  C CG1 . ILE C 1 276 ? 6.259   -7.203  -61.948  1.00 17.80  ? 269  ILE C CG1 1 
ATOM   9172  C CG2 . ILE C 1 276 ? 5.898   -5.488  -63.774  1.00 18.86  ? 269  ILE C CG2 1 
ATOM   9173  C CD1 . ILE C 1 276 ? 5.218   -6.580  -61.058  1.00 18.08  ? 269  ILE C CD1 1 
ATOM   9174  N N   . LEU C 1 277 ? 8.517   -6.119  -66.022  1.00 19.23  ? 270  LEU C N   1 
ATOM   9175  C CA  . LEU C 1 277 ? 8.985   -5.157  -67.040  1.00 19.90  ? 270  LEU C CA  1 
ATOM   9176  C C   . LEU C 1 277 ? 7.801   -4.364  -67.597  1.00 19.52  ? 270  LEU C C   1 
ATOM   9177  O O   . LEU C 1 277 ? 6.913   -4.975  -68.207  1.00 17.59  ? 270  LEU C O   1 
ATOM   9178  C CB  . LEU C 1 277 ? 9.691   -5.924  -68.151  1.00 20.94  ? 270  LEU C CB  1 
ATOM   9179  C CG  . LEU C 1 277 ? 11.205  -5.951  -68.068  1.00 22.96  ? 270  LEU C CG  1 
ATOM   9180  C CD1 . LEU C 1 277 ? 11.737  -6.327  -69.446  1.00 23.49  ? 270  LEU C CD1 1 
ATOM   9181  C CD2 . LEU C 1 277 ? 11.783  -4.615  -67.593  1.00 23.35  ? 270  LEU C CD2 1 
ATOM   9182  N N   . ASP C 1 278 ? 7.860   -3.045  -67.413  1.00 20.37  ? 271  ASP C N   1 
ATOM   9183  C CA  . ASP C 1 278 ? 6.916   -2.043  -67.957  1.00 21.88  ? 271  ASP C CA  1 
ATOM   9184  C C   . ASP C 1 278 ? 7.368   -1.628  -69.367  1.00 21.66  ? 271  ASP C C   1 
ATOM   9185  O O   . ASP C 1 278 ? 8.149   -0.654  -69.489  1.00 20.55  ? 271  ASP C O   1 
ATOM   9186  C CB  . ASP C 1 278 ? 6.825   -0.849  -67.004  1.00 23.41  ? 271  ASP C CB  1 
ATOM   9187  C CG  . ASP C 1 278 ? 5.848   0.223   -67.452  1.00 27.33  ? 271  ASP C CG  1 
ATOM   9188  O OD1 . ASP C 1 278 ? 5.347   0.122   -68.601  1.00 29.84  ? 271  ASP C OD1 1 
ATOM   9189  O OD2 . ASP C 1 278 ? 5.573   1.129   -66.655  1.00 28.11  ? 271  ASP C OD2 1 
ATOM   9190  N N   . GLU C 1 279 ? 6.896   -2.338  -70.395  1.00 21.39  ? 272  GLU C N   1 
ATOM   9191  C CA  . GLU C 1 279 ? 7.200   -2.031  -71.817  1.00 21.25  ? 272  GLU C CA  1 
ATOM   9192  C C   . GLU C 1 279 ? 6.018   -1.295  -72.459  1.00 21.92  ? 272  GLU C C   1 
ATOM   9193  O O   . GLU C 1 279 ? 5.872   -1.351  -73.672  1.00 20.50  ? 272  GLU C O   1 
ATOM   9194  C CB  . GLU C 1 279 ? 7.535   -3.314  -72.561  1.00 21.83  ? 272  GLU C CB  1 
ATOM   9195  C CG  . GLU C 1 279 ? 8.895   -3.829  -72.197  1.00 22.67  ? 272  GLU C CG  1 
ATOM   9196  C CD  . GLU C 1 279 ? 9.859   -4.044  -73.348  1.00 24.35  ? 272  GLU C CD  1 
ATOM   9197  O OE1 . GLU C 1 279 ? 9.738   -3.347  -74.402  1.00 26.50  ? 272  GLU C OE1 1 
ATOM   9198  O OE2 . GLU C 1 279 ? 10.735  -4.918  -73.189  1.00 26.40  ? 272  GLU C OE2 1 
ATOM   9199  N N   . VAL C 1 280 ? 5.208   -0.626  -71.648  1.00 22.99  ? 273  VAL C N   1 
ATOM   9200  C CA  . VAL C 1 280 ? 4.113   0.239   -72.143  1.00 24.24  ? 273  VAL C CA  1 
ATOM   9201  C C   . VAL C 1 280 ? 4.669   1.180   -73.211  1.00 25.33  ? 273  VAL C C   1 
ATOM   9202  O O   . VAL C 1 280 ? 3.993   1.370   -74.239  1.00 24.46  ? 273  VAL C O   1 
ATOM   9203  C CB  . VAL C 1 280 ? 3.452   1.005   -70.993  1.00 23.27  ? 273  VAL C CB  1 
ATOM   9204  C CG1 . VAL C 1 280 ? 2.626   2.186   -71.489  1.00 22.67  ? 273  VAL C CG1 1 
ATOM   9205  C CG2 . VAL C 1 280 ? 2.612   0.049   -70.170  1.00 24.22  ? 273  VAL C CG2 1 
ATOM   9206  N N   . GLN C 1 281 ? 5.832   1.774   -72.981  1.00 27.10  ? 274  GLN C N   1 
ATOM   9207  C CA  . GLN C 1 281 ? 6.330   2.810   -73.918  1.00 30.16  ? 274  GLN C CA  1 
ATOM   9208  C C   . GLN C 1 281 ? 7.469   2.294   -74.805  1.00 29.15  ? 274  GLN C C   1 
ATOM   9209  O O   . GLN C 1 281 ? 7.624   2.863   -75.904  1.00 30.47  ? 274  GLN C O   1 
ATOM   9210  C CB  . GLN C 1 281 ? 6.762   4.054   -73.167  1.00 34.29  ? 274  GLN C CB  1 
ATOM   9211  C CG  . GLN C 1 281 ? 7.002   5.206   -74.123  1.00 35.47  ? 274  GLN C CG  1 
ATOM   9212  C CD  . GLN C 1 281 ? 7.108   6.521   -73.402  1.00 39.34  ? 274  GLN C CD  1 
ATOM   9213  O OE1 . GLN C 1 281 ? 7.598   7.497   -73.967  1.00 37.01  ? 274  GLN C OE1 1 
ATOM   9214  N NE2 . GLN C 1 281 ? 6.667   6.552   -72.149  1.00 41.16  ? 274  GLN C NE2 1 
ATOM   9215  N N   . THR C 1 282 ? 8.168   1.229   -74.407  1.00 27.12  ? 275  THR C N   1 
ATOM   9216  C CA  . THR C 1 282 ? 9.287   0.647   -75.190  1.00 27.57  ? 275  THR C CA  1 
ATOM   9217  C C   . THR C 1 282 ? 8.831   -0.540  -76.041  1.00 27.60  ? 275  THR C C   1 
ATOM   9218  O O   . THR C 1 282 ? 9.674   -1.079  -76.768  1.00 29.46  ? 275  THR C O   1 
ATOM   9219  C CB  . THR C 1 282 ? 10.406  0.201   -74.257  1.00 28.57  ? 275  THR C CB  1 
ATOM   9220  O OG1 . THR C 1 282 ? 9.906   -0.837  -73.411  1.00 25.56  ? 275  THR C OG1 1 
ATOM   9221  C CG2 . THR C 1 282 ? 10.914  1.357   -73.428  1.00 29.85  ? 275  THR C CG2 1 
ATOM   9222  N N   . GLY C 1 283 ? 7.553   -0.919  -75.985  1.00 24.73  ? 276  GLY C N   1 
ATOM   9223  C CA  . GLY C 1 283 ? 7.034   -2.103  -76.687  1.00 23.09  ? 276  GLY C CA  1 
ATOM   9224  C C   . GLY C 1 283 ? 6.610   -1.804  -78.117  1.00 23.74  ? 276  GLY C C   1 
ATOM   9225  O O   . GLY C 1 283 ? 6.592   -0.622  -78.545  1.00 26.94  ? 276  GLY C O   1 
ATOM   9226  N N   . MET C 1 284 ? 6.269   -2.863  -78.844  1.00 22.39  ? 277  MET C N   1 
ATOM   9227  C CA  . MET C 1 284 ? 5.751   -2.802  -80.231  1.00 21.10  ? 277  MET C CA  1 
ATOM   9228  C C   . MET C 1 284 ? 6.787   -2.126  -81.149  1.00 21.21  ? 277  MET C C   1 
ATOM   9229  O O   . MET C 1 284 ? 6.401   -1.250  -81.962  1.00 19.61  ? 277  MET C O   1 
ATOM   9230  C CB  . MET C 1 284 ? 4.406   -2.065  -80.261  1.00 20.45  ? 277  MET C CB  1 
ATOM   9231  C CG  . MET C 1 284 ? 3.398   -2.580  -79.233  1.00 20.73  ? 277  MET C CG  1 
ATOM   9232  S SD  . MET C 1 284 ? 3.452   -4.363  -78.884  1.00 20.76  ? 277  MET C SD  1 
ATOM   9233  C CE  . MET C 1 284 ? 2.963   -5.085  -80.445  1.00 20.22  ? 277  MET C CE  1 
ATOM   9234  N N   . GLY C 1 285 ? 8.061   -2.527  -81.029  1.00 20.48  ? 278  GLY C N   1 
ATOM   9235  C CA  . GLY C 1 285 ? 9.103   -2.270  -82.034  1.00 20.30  ? 278  GLY C CA  1 
ATOM   9236  C C   . GLY C 1 285 ? 9.839   -0.954  -81.829  1.00 20.62  ? 278  GLY C C   1 
ATOM   9237  O O   . GLY C 1 285 ? 10.814  -0.716  -82.602  1.00 17.18  ? 278  GLY C O   1 
ATOM   9238  N N   . ARG C 1 286 ? 9.418   -0.103  -80.874  1.00 20.12  ? 279  ARG C N   1 
ATOM   9239  C CA  . ARG C 1 286 ? 9.901   1.308   -80.831  1.00 21.18  ? 279  ARG C CA  1 
ATOM   9240  C C   . ARG C 1 286 ? 11.441  1.407   -80.649  1.00 20.37  ? 279  ARG C C   1 
ATOM   9241  O O   . ARG C 1 286 ? 12.029  2.399   -81.144  1.00 19.22  ? 279  ARG C O   1 
ATOM   9242  C CB  . ARG C 1 286 ? 9.185   2.123   -79.754  1.00 21.72  ? 279  ARG C CB  1 
ATOM   9243  C CG  . ARG C 1 286 ? 9.824   3.496   -79.604  1.00 23.01  ? 279  ARG C CG  1 
ATOM   9244  C CD  . ARG C 1 286 ? 8.893   4.578   -79.170  1.00 22.59  ? 279  ARG C CD  1 
ATOM   9245  N NE  . ARG C 1 286 ? 7.791   4.758   -80.099  1.00 23.13  ? 279  ARG C NE  1 
ATOM   9246  C CZ  . ARG C 1 286 ? 7.803   5.556   -81.150  1.00 21.61  ? 279  ARG C CZ  1 
ATOM   9247  N NH1 . ARG C 1 286 ? 8.887   6.244   -81.471  1.00 21.84  ? 279  ARG C NH1 1 
ATOM   9248  N NH2 . ARG C 1 286 ? 6.710   5.648   -81.875  1.00 22.33  ? 279  ARG C NH2 1 
ATOM   9249  N N   . THR C 1 287 ? 12.093  0.464   -79.963  1.00 19.71  ? 280  THR C N   1 
ATOM   9250  C CA  . THR C 1 287 ? 13.544  0.568   -79.637  1.00 20.98  ? 280  THR C CA  1 
ATOM   9251  C C   . THR C 1 287 ? 14.388  -0.176  -80.659  1.00 20.51  ? 280  THR C C   1 
ATOM   9252  O O   . THR C 1 287 ? 15.594  -0.207  -80.493  1.00 23.14  ? 280  THR C O   1 
ATOM   9253  C CB  . THR C 1 287 ? 13.858  0.018   -78.245  1.00 21.82  ? 280  THR C CB  1 
ATOM   9254  O OG1 . THR C 1 287 ? 13.612  -1.391  -78.229  1.00 22.02  ? 280  THR C OG1 1 
ATOM   9255  C CG2 . THR C 1 287 ? 13.043  0.720   -77.181  1.00 23.80  ? 280  THR C CG2 1 
ATOM   9256  N N   . GLY C 1 288 ? 13.775  -0.765  -81.671  1.00 22.21  ? 281  GLY C N   1 
ATOM   9257  C CA  . GLY C 1 288 ? 14.501  -1.520  -82.711  1.00 22.53  ? 281  GLY C CA  1 
ATOM   9258  C C   . GLY C 1 288 ? 14.250  -3.009  -82.576  1.00 23.17  ? 281  GLY C C   1 
ATOM   9259  O O   . GLY C 1 288 ? 14.672  -3.752  -83.469  1.00 23.96  ? 281  GLY C O   1 
ATOM   9260  N N   . LYS C 1 289 ? 13.589  -3.441  -81.498  1.00 21.46  ? 282  LYS C N   1 
ATOM   9261  C CA  . LYS C 1 289 ? 13.054  -4.813  -81.401  1.00 21.65  ? 282  LYS C CA  1 
ATOM   9262  C C   . LYS C 1 289 ? 11.595  -4.709  -80.981  1.00 21.90  ? 282  LYS C C   1 
ATOM   9263  O O   . LYS C 1 289 ? 11.180  -3.616  -80.538  1.00 21.14  ? 282  LYS C O   1 
ATOM   9264  C CB  . LYS C 1 289 ? 13.832  -5.637  -80.381  1.00 23.80  ? 282  LYS C CB  1 
ATOM   9265  C CG  . LYS C 1 289 ? 15.333  -5.717  -80.587  1.00 26.70  ? 282  LYS C CG  1 
ATOM   9266  C CD  . LYS C 1 289 ? 15.721  -6.963  -81.358  1.00 29.53  ? 282  LYS C CD  1 
ATOM   9267  C CE  . LYS C 1 289 ? 17.208  -7.262  -81.314  1.00 31.22  ? 282  LYS C CE  1 
ATOM   9268  N NZ  . LYS C 1 289 ? 17.676  -7.756  -82.632  1.00 33.08  ? 282  LYS C NZ  1 
ATOM   9269  N N   . MET C 1 290 ? 10.854  -5.809  -81.097  1.00 22.48  ? 283  MET C N   1 
ATOM   9270  C CA  . MET C 1 290 ? 9.414   -5.845  -80.766  1.00 22.66  ? 283  MET C CA  1 
ATOM   9271  C C   . MET C 1 290 ? 9.274   -5.427  -79.296  1.00 22.16  ? 283  MET C C   1 
ATOM   9272  O O   . MET C 1 290 ? 8.381   -4.615  -79.003  1.00 22.40  ? 283  MET C O   1 
ATOM   9273  C CB  . MET C 1 290 ? 8.829   -7.237  -81.008  1.00 23.80  ? 283  MET C CB  1 
ATOM   9274  C CG  . MET C 1 290 ? 7.314   -7.292  -80.828  1.00 24.46  ? 283  MET C CG  1 
ATOM   9275  S SD  . MET C 1 290 ? 6.452   -6.088  -81.880  1.00 24.77  ? 283  MET C SD  1 
ATOM   9276  C CE  . MET C 1 290 ? 6.627   -6.803  -83.508  1.00 24.89  ? 283  MET C CE  1 
ATOM   9277  N N   . PHE C 1 291 ? 10.165  -5.903  -78.420  1.00 21.58  ? 284  PHE C N   1 
ATOM   9278  C CA  . PHE C 1 291 ? 10.261  -5.486  -76.993  1.00 21.62  ? 284  PHE C CA  1 
ATOM   9279  C C   . PHE C 1 291 ? 11.727  -5.173  -76.661  1.00 22.86  ? 284  PHE C C   1 
ATOM   9280  O O   . PHE C 1 291 ? 12.635  -5.874  -77.133  1.00 23.40  ? 284  PHE C O   1 
ATOM   9281  C CB  . PHE C 1 291 ? 9.715   -6.577  -76.073  1.00 20.47  ? 284  PHE C CB  1 
ATOM   9282  C CG  . PHE C 1 291 ? 8.422   -7.189  -76.537  1.00 21.81  ? 284  PHE C CG  1 
ATOM   9283  C CD1 . PHE C 1 291 ? 7.256   -6.445  -76.583  1.00 22.41  ? 284  PHE C CD1 1 
ATOM   9284  C CD2 . PHE C 1 291 ? 8.369   -8.512  -76.951  1.00 22.45  ? 284  PHE C CD2 1 
ATOM   9285  C CE1 . PHE C 1 291 ? 6.067   -7.017  -77.024  1.00 22.87  ? 284  PHE C CE1 1 
ATOM   9286  C CE2 . PHE C 1 291 ? 7.189   -9.078  -77.411  1.00 21.91  ? 284  PHE C CE2 1 
ATOM   9287  C CZ  . PHE C 1 291 ? 6.034   -8.331  -77.439  1.00 22.71  ? 284  PHE C CZ  1 
ATOM   9288  N N   . ALA C 1 292 ? 11.965  -4.146  -75.853  1.00 21.73  ? 285  ALA C N   1 
ATOM   9289  C CA  . ALA C 1 292 ? 13.319  -3.751  -75.432  1.00 21.00  ? 285  ALA C CA  1 
ATOM   9290  C C   . ALA C 1 292 ? 13.984  -4.886  -74.644  1.00 21.46  ? 285  ALA C C   1 
ATOM   9291  O O   . ALA C 1 292 ? 15.197  -4.902  -74.610  1.00 21.69  ? 285  ALA C O   1 
ATOM   9292  C CB  . ALA C 1 292 ? 13.270  -2.464  -74.651  1.00 20.55  ? 285  ALA C CB  1 
ATOM   9293  N N   . CYS C 1 293 ? 13.238  -5.815  -74.046  1.00 23.50  ? 286  CYS C N   1 
ATOM   9294  C CA  . CYS C 1 293 ? 13.810  -6.954  -73.277  1.00 24.13  ? 286  CYS C CA  1 
ATOM   9295  C C   . CYS C 1 293 ? 14.498  -7.936  -74.231  1.00 24.43  ? 286  CYS C C   1 
ATOM   9296  O O   . CYS C 1 293 ? 15.259  -8.776  -73.761  1.00 29.44  ? 286  CYS C O   1 
ATOM   9297  C CB  . CYS C 1 293 ? 12.767  -7.653  -72.418  1.00 24.45  ? 286  CYS C CB  1 
ATOM   9298  S SG  . CYS C 1 293 ? 11.498  -8.572  -73.333  1.00 30.91  ? 286  CYS C SG  1 
ATOM   9299  N N   . GLU C 1 294 ? 14.277  -7.817  -75.536  1.00 25.44  ? 287  GLU C N   1 
ATOM   9300  C CA  . GLU C 1 294 ? 14.879  -8.728  -76.549  1.00 26.49  ? 287  GLU C CA  1 
ATOM   9301  C C   . GLU C 1 294 ? 16.337  -8.338  -76.831  1.00 26.10  ? 287  GLU C C   1 
ATOM   9302  O O   . GLU C 1 294 ? 17.096  -9.229  -77.224  1.00 25.14  ? 287  GLU C O   1 
ATOM   9303  C CB  . GLU C 1 294 ? 14.038  -8.747  -77.822  1.00 28.21  ? 287  GLU C CB  1 
ATOM   9304  C CG  . GLU C 1 294 ? 12.681  -9.393  -77.596  1.00 30.78  ? 287  GLU C CG  1 
ATOM   9305  C CD  . GLU C 1 294 ? 11.743  -9.445  -78.781  1.00 31.20  ? 287  GLU C CD  1 
ATOM   9306  O OE1 . GLU C 1 294 ? 11.906  -8.643  -79.726  1.00 34.34  ? 287  GLU C OE1 1 
ATOM   9307  O OE2 . GLU C 1 294 ? 10.846  -10.285 -78.738  1.00 34.14  ? 287  GLU C OE2 1 
ATOM   9308  N N   . HIS C 1 295 ? 16.724  -7.079  -76.613  1.00 25.93  ? 288  HIS C N   1 
ATOM   9309  C CA  . HIS C 1 295 ? 18.128  -6.608  -76.747  1.00 28.12  ? 288  HIS C CA  1 
ATOM   9310  C C   . HIS C 1 295 ? 19.062  -7.490  -75.902  1.00 29.87  ? 288  HIS C C   1 
ATOM   9311  O O   . HIS C 1 295 ? 20.132  -7.854  -76.414  1.00 28.12  ? 288  HIS C O   1 
ATOM   9312  C CB  . HIS C 1 295 ? 18.266  -5.136  -76.365  1.00 28.96  ? 288  HIS C CB  1 
ATOM   9313  C CG  . HIS C 1 295 ? 17.571  -4.214  -77.303  1.00 28.68  ? 288  HIS C CG  1 
ATOM   9314  N ND1 . HIS C 1 295 ? 18.003  -4.015  -78.593  1.00 27.84  ? 288  HIS C ND1 1 
ATOM   9315  C CD2 . HIS C 1 295 ? 16.510  -3.399  -77.124  1.00 31.05  ? 288  HIS C CD2 1 
ATOM   9316  C CE1 . HIS C 1 295 ? 17.224  -3.132  -79.183  1.00 29.03  ? 288  HIS C CE1 1 
ATOM   9317  N NE2 . HIS C 1 295 ? 16.297  -2.737  -78.299  1.00 32.26  ? 288  HIS C NE2 1 
ATOM   9318  N N   . GLU C 1 296 ? 18.666  -7.853  -74.680  1.00 32.05  ? 289  GLU C N   1 
ATOM   9319  C CA  . GLU C 1 296 ? 19.506  -8.684  -73.776  1.00 35.25  ? 289  GLU C CA  1 
ATOM   9320  C C   . GLU C 1 296 ? 18.966  -10.122 -73.668  1.00 32.65  ? 289  GLU C C   1 
ATOM   9321  O O   . GLU C 1 296 ? 19.541  -10.918 -72.911  1.00 31.41  ? 289  GLU C O   1 
ATOM   9322  C CB  . GLU C 1 296 ? 19.612  -8.023  -72.396  1.00 42.32  ? 289  GLU C CB  1 
ATOM   9323  C CG  . GLU C 1 296 ? 20.610  -6.873  -72.348  1.00 48.59  ? 289  GLU C CG  1 
ATOM   9324  C CD  . GLU C 1 296 ? 20.954  -6.351  -70.949  1.00 52.00  ? 289  GLU C CD  1 
ATOM   9325  O OE1 . GLU C 1 296 ? 20.769  -7.100  -69.955  1.00 45.29  ? 289  GLU C OE1 1 
ATOM   9326  O OE2 . GLU C 1 296 ? 21.379  -5.173  -70.855  1.00 60.00  ? 289  GLU C OE2 1 
ATOM   9327  N N   A ASN C 1 297 ? 17.892  -10.444 -74.390  0.50 30.99  ? 290  ASN C N   1 
ATOM   9328  N N   B ASN C 1 297 ? 17.888  -10.443 -74.387  0.50 31.45  ? 290  ASN C N   1 
ATOM   9329  C CA  A ASN C 1 297 ? 17.167  -11.739 -74.264  0.50 30.84  ? 290  ASN C CA  1 
ATOM   9330  C CA  B ASN C 1 297 ? 17.202  -11.757 -74.271  0.50 31.63  ? 290  ASN C CA  1 
ATOM   9331  C C   A ASN C 1 297 ? 16.809  -11.967 -72.787  0.50 31.01  ? 290  ASN C C   1 
ATOM   9332  C C   B ASN C 1 297 ? 16.795  -11.973 -72.803  0.50 31.43  ? 290  ASN C C   1 
ATOM   9333  O O   A ASN C 1 297 ? 17.101  -13.065 -72.253  0.50 31.24  ? 290  ASN C O   1 
ATOM   9334  O O   B ASN C 1 297 ? 17.050  -13.080 -72.286  0.50 31.50  ? 290  ASN C O   1 
ATOM   9335  C CB  A ASN C 1 297 ? 17.960  -12.915 -74.842  0.50 30.83  ? 290  ASN C CB  1 
ATOM   9336  C CB  B ASN C 1 297 ? 18.084  -12.923 -74.752  0.50 32.16  ? 290  ASN C CB  1 
ATOM   9337  C CG  A ASN C 1 297 ? 17.069  -14.092 -75.207  0.50 30.33  ? 290  ASN C CG  1 
ATOM   9338  C CG  B ASN C 1 297 ? 18.801  -12.669 -76.066  0.50 32.49  ? 290  ASN C CG  1 
ATOM   9339  O OD1 A ASN C 1 297 ? 15.854  -13.949 -75.354  0.50 29.52  ? 290  ASN C OD1 1 
ATOM   9340  O OD1 B ASN C 1 297 ? 19.956  -12.235 -76.087  0.50 32.07  ? 290  ASN C OD1 1 
ATOM   9341  N ND2 A ASN C 1 297 ? 17.656  -15.269 -75.345  0.50 30.20  ? 290  ASN C ND2 1 
ATOM   9342  N ND2 B ASN C 1 297 ? 18.137  -12.965 -77.173  0.50 32.44  ? 290  ASN C ND2 1 
ATOM   9343  N N   . VAL C 1 298 ? 16.204  -10.953 -72.161  1.00 31.17  ? 291  VAL C N   1 
ATOM   9344  C CA  . VAL C 1 298 ? 15.701  -10.993 -70.756  1.00 30.98  ? 291  VAL C CA  1 
ATOM   9345  C C   . VAL C 1 298 ? 14.217  -11.386 -70.767  1.00 28.27  ? 291  VAL C C   1 
ATOM   9346  O O   . VAL C 1 298 ? 13.436  -10.737 -71.472  1.00 25.95  ? 291  VAL C O   1 
ATOM   9347  C CB  . VAL C 1 298 ? 15.938  -9.643  -70.051  1.00 32.23  ? 291  VAL C CB  1 
ATOM   9348  C CG1 . VAL C 1 298 ? 15.065  -9.446  -68.819  1.00 36.01  ? 291  VAL C CG1 1 
ATOM   9349  C CG2 . VAL C 1 298 ? 17.400  -9.511  -69.680  1.00 34.29  ? 291  VAL C CG2 1 
ATOM   9350  N N   . GLN C 1 299 ? 13.879  -12.431 -70.019  1.00 26.77  ? 292  GLN C N   1 
ATOM   9351  C CA  . GLN C 1 299 ? 12.495  -12.873 -69.799  1.00 28.32  ? 292  GLN C CA  1 
ATOM   9352  C C   . GLN C 1 299 ? 12.053  -12.445 -68.396  1.00 24.71  ? 292  GLN C C   1 
ATOM   9353  O O   . GLN C 1 299 ? 12.434  -13.063 -67.406  1.00 22.85  ? 292  GLN C O   1 
ATOM   9354  C CB  . GLN C 1 299 ? 12.394  -14.385 -70.017  1.00 33.57  ? 292  GLN C CB  1 
ATOM   9355  C CG  . GLN C 1 299 ? 10.944  -14.838 -70.212  1.00 39.62  ? 292  GLN C CG  1 
ATOM   9356  C CD  . GLN C 1 299 ? 10.593  -16.038 -69.368  1.00 43.37  ? 292  GLN C CD  1 
ATOM   9357  O OE1 . GLN C 1 299 ? 10.997  -17.166 -69.658  1.00 53.40  ? 292  GLN C OE1 1 
ATOM   9358  N NE2 . GLN C 1 299 ? 9.834   -15.791 -68.315  1.00 43.40  ? 292  GLN C NE2 1 
ATOM   9359  N N   . PRO C 1 300 ? 11.201  -11.403 -68.257  1.00 21.54  ? 293  PRO C N   1 
ATOM   9360  C CA  . PRO C 1 300 ? 10.588  -11.065 -66.988  1.00 20.42  ? 293  PRO C CA  1 
ATOM   9361  C C   . PRO C 1 300 ? 9.492   -12.091 -66.672  1.00 20.18  ? 293  PRO C C   1 
ATOM   9362  O O   . PRO C 1 300 ? 9.152   -12.875 -67.513  1.00 18.98  ? 293  PRO C O   1 
ATOM   9363  C CB  . PRO C 1 300 ? 10.025  -9.663  -67.241  1.00 19.86  ? 293  PRO C CB  1 
ATOM   9364  C CG  . PRO C 1 300 ? 9.598   -9.735  -68.659  1.00 21.42  ? 293  PRO C CG  1 
ATOM   9365  C CD  . PRO C 1 300 ? 10.704  -10.522 -69.320  1.00 22.75  ? 293  PRO C CD  1 
ATOM   9366  N N   . ASP C 1 301 ? 9.002   -12.073 -65.435  1.00 22.21  ? 294  ASP C N   1 
ATOM   9367  C CA  . ASP C 1 301 ? 7.869   -12.924 -64.977  1.00 23.20  ? 294  ASP C CA  1 
ATOM   9368  C C   . ASP C 1 301 ? 6.585   -12.361 -65.572  1.00 21.78  ? 294  ASP C C   1 
ATOM   9369  O O   . ASP C 1 301 ? 5.705   -13.155 -65.944  1.00 19.89  ? 294  ASP C O   1 
ATOM   9370  C CB  . ASP C 1 301 ? 7.822   -12.979 -63.453  1.00 23.41  ? 294  ASP C CB  1 
ATOM   9371  C CG  . ASP C 1 301 ? 9.043   -13.693 -62.916  1.00 25.73  ? 294  ASP C CG  1 
ATOM   9372  O OD1 . ASP C 1 301 ? 9.146   -14.877 -63.181  1.00 27.22  ? 294  ASP C OD1 1 
ATOM   9373  O OD2 . ASP C 1 301 ? 9.895   -13.048 -62.267  1.00 30.73  ? 294  ASP C OD2 1 
ATOM   9374  N N   . ILE C 1 302 ? 6.522   -11.029 -65.633  1.00 21.14  ? 295  ILE C N   1 
ATOM   9375  C CA  . ILE C 1 302 ? 5.323   -10.251 -66.032  1.00 20.06  ? 295  ILE C CA  1 
ATOM   9376  C C   . ILE C 1 302 ? 5.770   -9.109  -66.924  1.00 19.58  ? 295  ILE C C   1 
ATOM   9377  O O   . ILE C 1 302 ? 6.716   -8.395  -66.535  1.00 19.18  ? 295  ILE C O   1 
ATOM   9378  C CB  . ILE C 1 302 ? 4.560   -9.713  -64.811  1.00 20.34  ? 295  ILE C CB  1 
ATOM   9379  C CG1 . ILE C 1 302 ? 4.229   -10.815 -63.803  1.00 20.10  ? 295  ILE C CG1 1 
ATOM   9380  C CG2 . ILE C 1 302 ? 3.310   -8.986  -65.280  1.00 21.03  ? 295  ILE C CG2 1 
ATOM   9381  C CD1 . ILE C 1 302 ? 3.737   -10.302 -62.475  1.00 20.50  ? 295  ILE C CD1 1 
ATOM   9382  N N   . LEU C 1 303 ? 5.091   -8.988  -68.070  1.00 20.52  ? 296  LEU C N   1 
ATOM   9383  C CA  . LEU C 1 303 ? 5.334   -7.959  -69.101  1.00 19.35  ? 296  LEU C CA  1 
ATOM   9384  C C   . LEU C 1 303 ? 4.078   -7.097  -69.262  1.00 18.86  ? 296  LEU C C   1 
ATOM   9385  O O   . LEU C 1 303 ? 2.984   -7.652  -69.407  1.00 18.18  ? 296  LEU C O   1 
ATOM   9386  C CB  . LEU C 1 303 ? 5.719   -8.682  -70.386  1.00 19.67  ? 296  LEU C CB  1 
ATOM   9387  C CG  . LEU C 1 303 ? 5.933   -7.781  -71.606  1.00 20.08  ? 296  LEU C CG  1 
ATOM   9388  C CD1 . LEU C 1 303 ? 7.050   -6.774  -71.375  1.00 21.04  ? 296  LEU C CD1 1 
ATOM   9389  C CD2 . LEU C 1 303 ? 6.242   -8.615  -72.827  1.00 19.49  ? 296  LEU C CD2 1 
ATOM   9390  N N   . CYS C 1 304 ? 4.252   -5.780  -69.236  1.00 19.63  ? 297  CYS C N   1 
ATOM   9391  C CA  . CYS C 1 304 ? 3.173   -4.777  -69.395  1.00 20.06  ? 297  CYS C CA  1 
ATOM   9392  C C   . CYS C 1 304 ? 3.292   -4.071  -70.749  1.00 19.01  ? 297  CYS C C   1 
ATOM   9393  O O   . CYS C 1 304 ? 4.375   -3.593  -71.088  1.00 19.44  ? 297  CYS C O   1 
ATOM   9394  C CB  . CYS C 1 304 ? 3.228   -3.771  -68.259  1.00 22.51  ? 297  CYS C CB  1 
ATOM   9395  S SG  . CYS C 1 304 ? 3.023   -4.550  -66.638  1.00 26.46  ? 297  CYS C SG  1 
ATOM   9396  N N   . LEU C 1 305 ? 2.181   -3.991  -71.462  1.00 18.53  ? 298  LEU C N   1 
ATOM   9397  C CA  . LEU C 1 305 ? 2.065   -3.362  -72.799  1.00 18.63  ? 298  LEU C CA  1 
ATOM   9398  C C   . LEU C 1 305 ? 0.822   -2.480  -72.841  1.00 18.66  ? 298  LEU C C   1 
ATOM   9399  O O   . LEU C 1 305 ? -0.205  -2.860  -72.248  1.00 17.85  ? 298  LEU C O   1 
ATOM   9400  C CB  . LEU C 1 305 ? 1.919   -4.453  -73.855  1.00 18.02  ? 298  LEU C CB  1 
ATOM   9401  C CG  . LEU C 1 305 ? 3.054   -5.454  -73.959  1.00 18.77  ? 298  LEU C CG  1 
ATOM   9402  C CD1 . LEU C 1 305 ? 2.726   -6.477  -75.043  1.00 19.06  ? 298  LEU C CD1 1 
ATOM   9403  C CD2 . LEU C 1 305 ? 4.374   -4.750  -74.243  1.00 18.95  ? 298  LEU C CD2 1 
ATOM   9404  N N   . ALA C 1 306 ? 0.929   -1.373  -73.569  1.00 19.01  ? 299  ALA C N   1 
ATOM   9405  C CA  . ALA C 1 306 ? -0.196  -0.508  -73.982  1.00 19.48  ? 299  ALA C CA  1 
ATOM   9406  C C   . ALA C 1 306 ? 0.295   0.384   -75.127  1.00 18.67  ? 299  ALA C C   1 
ATOM   9407  O O   . ALA C 1 306 ? 1.077   -0.112  -75.919  1.00 17.29  ? 299  ALA C O   1 
ATOM   9408  C CB  . ALA C 1 306 ? -0.712  0.265   -72.785  1.00 20.01  ? 299  ALA C CB  1 
ATOM   9409  N N   . LYS C 1 307 ? -0.131  1.648   -75.165  1.00 19.98  ? 300  LYS C N   1 
ATOM   9410  C CA  . LYS C 1 307 ? 0.156   2.655   -76.224  1.00 20.88  ? 300  LYS C CA  1 
ATOM   9411  C C   . LYS C 1 307 ? 0.073   2.006   -77.613  1.00 20.73  ? 300  LYS C C   1 
ATOM   9412  O O   . LYS C 1 307 ? -1.037  1.791   -78.087  1.00 20.77  ? 300  LYS C O   1 
ATOM   9413  C CB  . LYS C 1 307 ? 1.499   3.327   -75.919  1.00 21.55  ? 300  LYS C CB  1 
ATOM   9414  C CG  . LYS C 1 307 ? 1.544   3.983   -74.556  1.00 22.68  ? 300  LYS C CG  1 
ATOM   9415  C CD  . LYS C 1 307 ? 2.622   5.016   -74.358  1.00 22.99  ? 300  LYS C CD  1 
ATOM   9416  C CE  . LYS C 1 307 ? 2.065   6.187   -73.576  1.00 23.11  ? 300  LYS C CE  1 
ATOM   9417  N NZ  . LYS C 1 307 ? 3.110   7.085   -73.048  1.00 23.57  ? 300  LYS C NZ  1 
ATOM   9418  N N   . ALA C 1 308 ? 1.214   1.686   -78.233  1.00 21.27  ? 301  ALA C N   1 
ATOM   9419  C CA  . ALA C 1 308 ? 1.301   1.287   -79.652  1.00 20.76  ? 301  ALA C CA  1 
ATOM   9420  C C   . ALA C 1 308 ? 0.557   -0.031  -79.885  1.00 20.75  ? 301  ALA C C   1 
ATOM   9421  O O   . ALA C 1 308 ? 0.199   -0.271  -81.029  1.00 19.21  ? 301  ALA C O   1 
ATOM   9422  C CB  . ALA C 1 308 ? 2.738   1.207   -80.075  1.00 21.34  ? 301  ALA C CB  1 
ATOM   9423  N N   . LEU C 1 309 ? 0.310   -0.848  -78.857  1.00 20.55  ? 302  LEU C N   1 
ATOM   9424  C CA  . LEU C 1 309 ? -0.399  -2.143  -79.037  1.00 20.91  ? 302  LEU C CA  1 
ATOM   9425  C C   . LEU C 1 309 ? -1.766  -1.932  -79.710  1.00 21.31  ? 302  LEU C C   1 
ATOM   9426  O O   . LEU C 1 309 ? -2.240  -2.876  -80.355  1.00 22.31  ? 302  LEU C O   1 
ATOM   9427  C CB  . LEU C 1 309 ? -0.568  -2.825  -77.682  1.00 20.37  ? 302  LEU C CB  1 
ATOM   9428  C CG  . LEU C 1 309 ? -1.176  -4.226  -77.738  1.00 20.33  ? 302  LEU C CG  1 
ATOM   9429  C CD1 . LEU C 1 309 ? -0.342  -5.156  -78.615  1.00 20.63  ? 302  LEU C CD1 1 
ATOM   9430  C CD2 . LEU C 1 309 ? -1.318  -4.800  -76.334  1.00 20.34  ? 302  LEU C CD2 1 
ATOM   9431  N N   . GLY C 1 310 ? -2.392  -0.759  -79.565  1.00 20.73  ? 303  GLY C N   1 
ATOM   9432  C CA  . GLY C 1 310 ? -3.722  -0.479  -80.151  1.00 20.76  ? 303  GLY C CA  1 
ATOM   9433  C C   . GLY C 1 310 ? -3.650  0.108   -81.545  1.00 20.20  ? 303  GLY C C   1 
ATOM   9434  O O   . GLY C 1 310 ? -4.705  0.366   -82.140  1.00 20.16  ? 303  GLY C O   1 
ATOM   9435  N N   . GLY C 1 311 ? -2.448  0.339   -82.053  1.00 20.87  ? 304  GLY C N   1 
ATOM   9436  C CA  . GLY C 1 311 ? -2.218  0.723   -83.459  1.00 21.69  ? 304  GLY C CA  1 
ATOM   9437  C C   . GLY C 1 311 ? -2.500  2.187   -83.726  1.00 22.04  ? 304  GLY C C   1 
ATOM   9438  O O   . GLY C 1 311 ? -2.588  2.538   -84.916  1.00 24.49  ? 304  GLY C O   1 
ATOM   9439  N N   . GLY C 1 312 ? -2.618  3.014   -82.685  1.00 20.27  ? 305  GLY C N   1 
ATOM   9440  C CA  . GLY C 1 312 ? -2.973  4.439   -82.824  1.00 20.28  ? 305  GLY C CA  1 
ATOM   9441  C C   . GLY C 1 312 ? -4.427  4.591   -83.232  1.00 21.05  ? 305  GLY C C   1 
ATOM   9442  O O   . GLY C 1 312 ? -4.801  5.651   -83.785  1.00 22.11  ? 305  GLY C O   1 
ATOM   9443  N N   . VAL C 1 313 ? -5.232  3.563   -82.978  1.00 20.78  ? 306  VAL C N   1 
ATOM   9444  C CA  . VAL C 1 313 ? -6.687  3.593   -83.268  1.00 21.55  ? 306  VAL C CA  1 
ATOM   9445  C C   . VAL C 1 313 ? -7.480  3.326   -81.983  1.00 23.36  ? 306  VAL C C   1 
ATOM   9446  O O   . VAL C 1 313 ? -8.396  4.141   -81.681  1.00 20.31  ? 306  VAL C O   1 
ATOM   9447  C CB  . VAL C 1 313 ? -7.035  2.604   -84.396  1.00 22.27  ? 306  VAL C CB  1 
ATOM   9448  C CG1 . VAL C 1 313 ? -8.514  2.683   -84.774  1.00 21.50  ? 306  VAL C CG1 1 
ATOM   9449  C CG2 . VAL C 1 313 ? -6.158  2.849   -85.618  1.00 21.50  ? 306  VAL C CG2 1 
ATOM   9450  N N   . MET C 1 314 ? -7.137  2.254   -81.249  1.00 26.08  ? 307  MET C N   1 
ATOM   9451  C CA  . MET C 1 314 ? -7.870  1.798   -80.032  1.00 26.47  ? 307  MET C CA  1 
ATOM   9452  C C   . MET C 1 314 ? -7.004  1.926   -78.783  1.00 26.72  ? 307  MET C C   1 
ATOM   9453  O O   . MET C 1 314 ? -5.796  1.671   -78.814  1.00 25.10  ? 307  MET C O   1 
ATOM   9454  C CB  . MET C 1 314 ? -8.326  0.338   -80.148  1.00 27.32  ? 307  MET C CB  1 
ATOM   9455  C CG  . MET C 1 314 ? -9.546  0.157   -81.041  1.00 27.30  ? 307  MET C CG  1 
ATOM   9456  S SD  . MET C 1 314 ? -10.966 1.131   -80.477  1.00 29.88  ? 307  MET C SD  1 
ATOM   9457  C CE  . MET C 1 314 ? -11.475 0.137   -79.075  1.00 28.09  ? 307  MET C CE  1 
ATOM   9458  N N   . PRO C 1 315 ? -7.619  2.314   -77.640  1.00 24.95  ? 308  PRO C N   1 
ATOM   9459  C CA  . PRO C 1 315 ? -6.994  2.150   -76.339  1.00 26.04  ? 308  PRO C CA  1 
ATOM   9460  C C   . PRO C 1 315 ? -7.045  0.665   -75.974  1.00 26.58  ? 308  PRO C C   1 
ATOM   9461  O O   . PRO C 1 315 ? -8.098  0.071   -76.042  1.00 23.55  ? 308  PRO C O   1 
ATOM   9462  C CB  . PRO C 1 315 ? -7.892  2.975   -75.412  1.00 25.41  ? 308  PRO C CB  1 
ATOM   9463  C CG  . PRO C 1 315 ? -9.242  2.875   -76.043  1.00 24.95  ? 308  PRO C CG  1 
ATOM   9464  C CD  . PRO C 1 315 ? -8.957  2.917   -77.527  1.00 24.93  ? 308  PRO C CD  1 
ATOM   9465  N N   . ILE C 1 316 ? -5.893  0.108   -75.621  1.00 28.48  ? 309  ILE C N   1 
ATOM   9466  C CA  . ILE C 1 316 ? -5.765  -1.281  -75.090  1.00 29.93  ? 309  ILE C CA  1 
ATOM   9467  C C   . ILE C 1 316 ? -4.523  -1.345  -74.203  1.00 28.32  ? 309  ILE C C   1 
ATOM   9468  O O   . ILE C 1 316 ? -3.563  -0.604  -74.472  1.00 30.21  ? 309  ILE C O   1 
ATOM   9469  C CB  . ILE C 1 316 ? -5.698  -2.311  -76.235  1.00 30.22  ? 309  ILE C CB  1 
ATOM   9470  C CG1 . ILE C 1 316 ? -5.674  -3.754  -75.720  1.00 29.33  ? 309  ILE C CG1 1 
ATOM   9471  C CG2 . ILE C 1 316 ? -4.514  -2.018  -77.149  1.00 32.60  ? 309  ILE C CG2 1 
ATOM   9472  C CD1 . ILE C 1 316 ? -5.743  -4.787  -76.820  1.00 28.63  ? 309  ILE C CD1 1 
ATOM   9473  N N   . GLY C 1 317 ? -4.567  -2.202  -73.186  1.00 26.80  ? 310  GLY C N   1 
ATOM   9474  C CA  . GLY C 1 317 ? -3.387  -2.647  -72.428  1.00 25.63  ? 310  GLY C CA  1 
ATOM   9475  C C   . GLY C 1 317 ? -3.351  -4.159  -72.376  1.00 24.72  ? 310  GLY C C   1 
ATOM   9476  O O   . GLY C 1 317 ? -4.419  -4.796  -72.520  1.00 23.26  ? 310  GLY C O   1 
ATOM   9477  N N   . ALA C 1 318 ? -2.166  -4.729  -72.190  1.00 23.91  ? 311  ALA C N   1 
ATOM   9478  C CA  . ALA C 1 318 ? -1.999  -6.183  -71.993  1.00 24.56  ? 311  ALA C CA  1 
ATOM   9479  C C   . ALA C 1 318 ? -0.983  -6.429  -70.889  1.00 24.56  ? 311  ALA C C   1 
ATOM   9480  O O   . ALA C 1 318 ? 0.068   -5.751  -70.864  1.00 25.25  ? 311  ALA C O   1 
ATOM   9481  C CB  . ALA C 1 318 ? -1.567  -6.843  -73.271  1.00 26.27  ? 311  ALA C CB  1 
ATOM   9482  N N   . THR C 1 319 ? -1.299  -7.380  -70.022  1.00 22.62  ? 312  THR C N   1 
ATOM   9483  C CA  . THR C 1 319 ? -0.380  -7.898  -68.996  1.00 21.69  ? 312  THR C CA  1 
ATOM   9484  C C   . THR C 1 319 ? -0.176  -9.368  -69.317  1.00 21.12  ? 312  THR C C   1 
ATOM   9485  O O   . THR C 1 319 ? -1.163  -10.101 -69.314  1.00 20.18  ? 312  THR C O   1 
ATOM   9486  C CB  . THR C 1 319 ? -0.962  -7.649  -67.608  1.00 22.72  ? 312  THR C CB  1 
ATOM   9487  O OG1 . THR C 1 319 ? -1.320  -6.268  -67.536  1.00 22.95  ? 312  THR C OG1 1 
ATOM   9488  C CG2 . THR C 1 319 ? 0.012   -8.003  -66.511  1.00 22.67  ? 312  THR C CG2 1 
ATOM   9489  N N   . ILE C 1 320 ? 1.052   -9.754  -69.635  1.00 21.57  ? 313  ILE C N   1 
ATOM   9490  C CA  . ILE C 1 320 ? 1.407   -11.155 -69.990  1.00 22.95  ? 313  ILE C CA  1 
ATOM   9491  C C   . ILE C 1 320 ? 2.326   -11.673 -68.903  1.00 21.79  ? 313  ILE C C   1 
ATOM   9492  O O   . ILE C 1 320 ? 3.169   -10.898 -68.447  1.00 23.26  ? 313  ILE C O   1 
ATOM   9493  C CB  . ILE C 1 320 ? 2.076   -11.237 -71.374  1.00 25.66  ? 313  ILE C CB  1 
ATOM   9494  C CG1 . ILE C 1 320 ? 1.314   -10.398 -72.403  1.00 28.61  ? 313  ILE C CG1 1 
ATOM   9495  C CG2 . ILE C 1 320 ? 2.211   -12.686 -71.836  1.00 25.40  ? 313  ILE C CG2 1 
ATOM   9496  C CD1 . ILE C 1 320 ? 2.162   -9.375  -73.108  1.00 29.87  ? 313  ILE C CD1 1 
ATOM   9497  N N   . ALA C 1 321 ? 2.168   -12.939 -68.536  1.00 20.88  ? 314  ALA C N   1 
ATOM   9498  C CA  . ALA C 1 321 ? 2.913   -13.573 -67.432  1.00 20.60  ? 314  ALA C CA  1 
ATOM   9499  C C   . ALA C 1 321 ? 3.088   -15.063 -67.713  1.00 21.17  ? 314  ALA C C   1 
ATOM   9500  O O   . ALA C 1 321 ? 2.406   -15.600 -68.590  1.00 21.31  ? 314  ALA C O   1 
ATOM   9501  C CB  . ALA C 1 321 ? 2.188   -13.343 -66.139  1.00 19.89  ? 314  ALA C CB  1 
ATOM   9502  N N   . THR C 1 322 ? 3.978   -15.682 -66.946  1.00 22.17  ? 315  THR C N   1 
ATOM   9503  C CA  . THR C 1 322 ? 4.218   -17.145 -66.920  1.00 22.05  ? 315  THR C CA  1 
ATOM   9504  C C   . THR C 1 322 ? 2.948   -17.844 -66.445  1.00 21.69  ? 315  THR C C   1 
ATOM   9505  O O   . THR C 1 322 ? 2.159   -17.209 -65.739  1.00 22.08  ? 315  THR C O   1 
ATOM   9506  C CB  . THR C 1 322 ? 5.403   -17.475 -66.007  1.00 21.79  ? 315  THR C CB  1 
ATOM   9507  O OG1 . THR C 1 322 ? 5.117   -16.885 -64.745  1.00 21.02  ? 315  THR C OG1 1 
ATOM   9508  C CG2 . THR C 1 322 ? 6.716   -16.927 -66.514  1.00 21.15  ? 315  THR C CG2 1 
ATOM   9509  N N   . GLU C 1 323 ? 2.781   -19.113 -66.800  1.00 22.74  ? 316  GLU C N   1 
ATOM   9510  C CA  . GLU C 1 323 ? 1.697   -19.974 -66.264  1.00 25.32  ? 316  GLU C CA  1 
ATOM   9511  C C   . GLU C 1 323 ? 1.854   -20.041 -64.741  1.00 24.38  ? 316  GLU C C   1 
ATOM   9512  O O   . GLU C 1 323 ? 0.830   -20.011 -64.055  1.00 24.78  ? 316  GLU C O   1 
ATOM   9513  C CB  . GLU C 1 323 ? 1.757   -21.356 -66.909  1.00 27.62  ? 316  GLU C CB  1 
ATOM   9514  C CG  . GLU C 1 323 ? 0.708   -22.327 -66.409  1.00 31.46  ? 316  GLU C CG  1 
ATOM   9515  C CD  . GLU C 1 323 ? 0.250   -23.354 -67.449  1.00 36.39  ? 316  GLU C CD  1 
ATOM   9516  O OE1 . GLU C 1 323 ? 0.708   -23.285 -68.626  1.00 39.22  ? 316  GLU C OE1 1 
ATOM   9517  O OE2 . GLU C 1 323 ? -0.600  -24.214 -67.103  1.00 45.53  ? 316  GLU C OE2 1 
ATOM   9518  N N   . GLU C 1 324 ? 3.099   -20.093 -64.260  1.00 25.83  ? 317  GLU C N   1 
ATOM   9519  C CA  . GLU C 1 324 ? 3.472   -20.205 -62.819  1.00 27.88  ? 317  GLU C CA  1 
ATOM   9520  C C   . GLU C 1 324 ? 2.788   -19.073 -62.038  1.00 24.61  ? 317  GLU C C   1 
ATOM   9521  O O   . GLU C 1 324 ? 2.130   -19.373 -61.040  1.00 21.98  ? 317  GLU C O   1 
ATOM   9522  C CB  . GLU C 1 324 ? 5.008   -20.207 -62.656  1.00 31.63  ? 317  GLU C CB  1 
ATOM   9523  C CG  . GLU C 1 324 ? 5.519   -20.361 -61.219  1.00 35.25  ? 317  GLU C CG  1 
ATOM   9524  C CD  . GLU C 1 324 ? 4.982   -21.553 -60.437  1.00 39.96  ? 317  GLU C CD  1 
ATOM   9525  O OE1 . GLU C 1 324 ? 4.663   -22.578 -61.071  1.00 46.87  ? 317  GLU C OE1 1 
ATOM   9526  O OE2 . GLU C 1 324 ? 4.862   -21.457 -59.189  1.00 45.51  ? 317  GLU C OE2 1 
ATOM   9527  N N   . VAL C 1 325 ? 2.902   -17.835 -62.528  1.00 22.30  ? 318  VAL C N   1 
ATOM   9528  C CA  . VAL C 1 325 ? 2.388   -16.602 -61.865  1.00 21.51  ? 318  VAL C CA  1 
ATOM   9529  C C   . VAL C 1 325 ? 0.891   -16.429 -62.173  1.00 21.92  ? 318  VAL C C   1 
ATOM   9530  O O   . VAL C 1 325 ? 0.120   -16.145 -61.243  1.00 22.53  ? 318  VAL C O   1 
ATOM   9531  C CB  . VAL C 1 325 ? 3.177   -15.379 -62.356  1.00 20.95  ? 318  VAL C CB  1 
ATOM   9532  C CG1 . VAL C 1 325 ? 2.513   -14.064 -61.967  1.00 20.82  ? 318  VAL C CG1 1 
ATOM   9533  C CG2 . VAL C 1 325 ? 4.620   -15.441 -61.879  1.00 21.28  ? 318  VAL C CG2 1 
ATOM   9534  N N   . PHE C 1 326 ? 0.488   -16.524 -63.443  1.00 21.26  ? 319  PHE C N   1 
ATOM   9535  C CA  . PHE C 1 326 ? -0.879  -16.173 -63.887  1.00 19.74  ? 319  PHE C CA  1 
ATOM   9536  C C   . PHE C 1 326 ? -1.867  -17.177 -63.291  1.00 19.13  ? 319  PHE C C   1 
ATOM   9537  O O   . PHE C 1 326 ? -3.009  -16.772 -63.033  1.00 17.95  ? 319  PHE C O   1 
ATOM   9538  C CB  . PHE C 1 326 ? -0.939  -16.135 -65.414  1.00 20.47  ? 319  PHE C CB  1 
ATOM   9539  C CG  . PHE C 1 326 ? -1.993  -15.233 -66.002  1.00 19.44  ? 319  PHE C CG  1 
ATOM   9540  C CD1 . PHE C 1 326 ? -3.297  -15.669 -66.141  1.00 18.74  ? 319  PHE C CD1 1 
ATOM   9541  C CD2 . PHE C 1 326 ? -1.663  -13.970 -66.468  1.00 19.93  ? 319  PHE C CD2 1 
ATOM   9542  C CE1 . PHE C 1 326 ? -4.256  -14.860 -66.728  1.00 18.64  ? 319  PHE C CE1 1 
ATOM   9543  C CE2 . PHE C 1 326 ? -2.627  -13.155 -67.035  1.00 20.64  ? 319  PHE C CE2 1 
ATOM   9544  C CZ  . PHE C 1 326 ? -3.921  -13.606 -67.168  1.00 19.09  ? 319  PHE C CZ  1 
ATOM   9545  N N   . SER C 1 327 ? -1.430  -18.418 -63.035  1.00 19.46  ? 320  SER C N   1 
ATOM   9546  C CA  . SER C 1 327 ? -2.293  -19.525 -62.533  1.00 20.91  ? 320  SER C CA  1 
ATOM   9547  C C   . SER C 1 327 ? -3.001  -19.125 -61.230  1.00 20.88  ? 320  SER C C   1 
ATOM   9548  O O   . SER C 1 327 ? -3.922  -19.875 -60.804  1.00 20.97  ? 320  SER C O   1 
ATOM   9549  C CB  . SER C 1 327 ? -1.518  -20.816 -62.359  1.00 21.36  ? 320  SER C CB  1 
ATOM   9550  O OG  . SER C 1 327 ? -0.504  -20.668 -61.372  1.00 21.91  ? 320  SER C OG  1 
ATOM   9551  N N   . VAL C 1 328 ? -2.614  -17.992 -60.627  1.00 20.30  ? 321  VAL C N   1 
ATOM   9552  C CA  . VAL C 1 328 ? -3.290  -17.432 -59.416  1.00 20.19  ? 321  VAL C CA  1 
ATOM   9553  C C   . VAL C 1 328 ? -4.734  -17.056 -59.760  1.00 21.30  ? 321  VAL C C   1 
ATOM   9554  O O   . VAL C 1 328 ? -5.524  -16.951 -58.799  1.00 21.17  ? 321  VAL C O   1 
ATOM   9555  C CB  . VAL C 1 328 ? -2.540  -16.234 -58.794  1.00 19.15  ? 321  VAL C CB  1 
ATOM   9556  C CG1 . VAL C 1 328 ? -1.180  -16.644 -58.268  1.00 18.93  ? 321  VAL C CG1 1 
ATOM   9557  C CG2 . VAL C 1 328 ? -2.426  -15.049 -59.742  1.00 19.28  ? 321  VAL C CG2 1 
ATOM   9558  N N   . LEU C 1 329 ? -5.059  -16.869 -61.051  1.00 22.24  ? 322  LEU C N   1 
ATOM   9559  C CA  . LEU C 1 329 ? -6.395  -16.412 -61.524  1.00 23.92  ? 322  LEU C CA  1 
ATOM   9560  C C   . LEU C 1 329 ? -7.265  -17.582 -61.992  1.00 25.39  ? 322  LEU C C   1 
ATOM   9561  O O   . LEU C 1 329 ? -8.413  -17.317 -62.313  1.00 25.73  ? 322  LEU C O   1 
ATOM   9562  C CB  . LEU C 1 329 ? -6.220  -15.399 -62.656  1.00 23.13  ? 322  LEU C CB  1 
ATOM   9563  C CG  . LEU C 1 329 ? -5.412  -14.139 -62.329  1.00 23.69  ? 322  LEU C CG  1 
ATOM   9564  C CD1 . LEU C 1 329 ? -5.487  -13.153 -63.488  1.00 24.16  ? 322  LEU C CD1 1 
ATOM   9565  C CD2 . LEU C 1 329 ? -5.866  -13.469 -61.042  1.00 23.06  ? 322  LEU C CD2 1 
ATOM   9566  N N   . PHE C 1 330 ? -6.763  -18.817 -61.961  1.00 27.70  ? 323  PHE C N   1 
ATOM   9567  C CA  . PHE C 1 330 ? -7.411  -20.009 -62.574  1.00 30.41  ? 323  PHE C CA  1 
ATOM   9568  C C   . PHE C 1 330 ? -8.567  -20.554 -61.721  1.00 33.61  ? 323  PHE C C   1 
ATOM   9569  O O   . PHE C 1 330 ? -9.549  -21.004 -62.341  1.00 32.55  ? 323  PHE C O   1 
ATOM   9570  C CB  . PHE C 1 330 ? -6.382  -21.112 -62.820  1.00 32.57  ? 323  PHE C CB  1 
ATOM   9571  C CG  . PHE C 1 330 ? -5.386  -20.839 -63.925  1.00 33.91  ? 323  PHE C CG  1 
ATOM   9572  C CD1 . PHE C 1 330 ? -5.372  -19.633 -64.620  1.00 33.66  ? 323  PHE C CD1 1 
ATOM   9573  C CD2 . PHE C 1 330 ? -4.430  -21.793 -64.246  1.00 35.05  ? 323  PHE C CD2 1 
ATOM   9574  C CE1 . PHE C 1 330 ? -4.446  -19.407 -65.629  1.00 34.47  ? 323  PHE C CE1 1 
ATOM   9575  C CE2 . PHE C 1 330 ? -3.499  -21.559 -65.249  1.00 38.75  ? 323  PHE C CE2 1 
ATOM   9576  C CZ  . PHE C 1 330 ? -3.511  -20.367 -65.942  1.00 36.75  ? 323  PHE C CZ  1 
ATOM   9577  N N   . ASP C 1 331 ? -8.455  -20.575 -60.385  1.00 38.03  ? 324  ASP C N   1 
ATOM   9578  C CA  . ASP C 1 331 ? -9.484  -21.183 -59.491  1.00 41.70  ? 324  ASP C CA  1 
ATOM   9579  C C   . ASP C 1 331 ? -10.690 -20.251 -59.395  1.00 36.65  ? 324  ASP C C   1 
ATOM   9580  O O   . ASP C 1 331 ? -11.801 -20.765 -59.302  1.00 32.16  ? 324  ASP C O   1 
ATOM   9581  C CB  . ASP C 1 331 ? -8.978  -21.473 -58.074  1.00 51.84  ? 324  ASP C CB  1 
ATOM   9582  C CG  . ASP C 1 331 ? -8.189  -22.764 -57.966  1.00 65.92  ? 324  ASP C CG  1 
ATOM   9583  O OD1 . ASP C 1 331 ? -7.874  -23.345 -59.026  1.00 79.98  ? 324  ASP C OD1 1 
ATOM   9584  O OD2 . ASP C 1 331 ? -7.893  -23.184 -56.820  1.00 83.25  ? 324  ASP C OD2 1 
ATOM   9585  N N   . ASN C 1 332 ? -10.445 -18.941 -59.341  1.00 34.37  ? 325  ASN C N   1 
ATOM   9586  C CA  . ASN C 1 332 ? -11.484 -17.883 -59.381  1.00 31.70  ? 325  ASN C CA  1 
ATOM   9587  C C   . ASN C 1 332 ? -11.113 -16.888 -60.472  1.00 29.68  ? 325  ASN C C   1 
ATOM   9588  O O   . ASN C 1 332 ? -10.387 -15.922 -60.239  1.00 27.09  ? 325  ASN C O   1 
ATOM   9589  C CB  . ASN C 1 332 ? -11.682 -17.166 -58.048  1.00 32.50  ? 325  ASN C CB  1 
ATOM   9590  C CG  . ASN C 1 332 ? -12.849 -16.201 -58.104  1.00 33.14  ? 325  ASN C CG  1 
ATOM   9591  O OD1 . ASN C 1 332 ? -13.589 -16.167 -59.087  1.00 31.50  ? 325  ASN C OD1 1 
ATOM   9592  N ND2 . ASN C 1 332 ? -13.021 -15.402 -57.063  1.00 34.04  ? 325  ASN C ND2 1 
ATOM   9593  N N   . PRO C 1 333 ? -11.640 -17.092 -61.695  1.00 28.95  ? 326  PRO C N   1 
ATOM   9594  C CA  . PRO C 1 333 ? -11.334 -16.209 -62.816  1.00 28.77  ? 326  PRO C CA  1 
ATOM   9595  C C   . PRO C 1 333 ? -11.941 -14.800 -62.701  1.00 27.51  ? 326  PRO C C   1 
ATOM   9596  O O   . PRO C 1 333 ? -11.690 -13.989 -63.566  1.00 30.33  ? 326  PRO C O   1 
ATOM   9597  C CB  . PRO C 1 333 ? -11.902 -16.976 -64.021  1.00 28.91  ? 326  PRO C CB  1 
ATOM   9598  C CG  . PRO C 1 333 ? -13.016 -17.794 -63.437  1.00 30.83  ? 326  PRO C CG  1 
ATOM   9599  C CD  . PRO C 1 333 ? -12.546 -18.189 -62.057  1.00 29.91  ? 326  PRO C CD  1 
ATOM   9600  N N   . PHE C 1 334 ? -12.701 -14.517 -61.647  1.00 25.49  ? 327  PHE C N   1 
ATOM   9601  C CA  . PHE C 1 334 ? -13.287 -13.174 -61.415  1.00 26.18  ? 327  PHE C CA  1 
ATOM   9602  C C   . PHE C 1 334 ? -12.429 -12.413 -60.413  1.00 26.31  ? 327  PHE C C   1 
ATOM   9603  O O   . PHE C 1 334 ? -12.792 -11.289 -60.069  1.00 30.41  ? 327  PHE C O   1 
ATOM   9604  C CB  . PHE C 1 334 ? -14.753 -13.288 -60.987  1.00 26.70  ? 327  PHE C CB  1 
ATOM   9605  C CG  . PHE C 1 334 ? -15.559 -14.021 -62.022  1.00 27.40  ? 327  PHE C CG  1 
ATOM   9606  C CD1 . PHE C 1 334 ? -15.800 -13.435 -63.254  1.00 29.90  ? 327  PHE C CD1 1 
ATOM   9607  C CD2 . PHE C 1 334 ? -15.957 -15.330 -61.821  1.00 28.13  ? 327  PHE C CD2 1 
ATOM   9608  C CE1 . PHE C 1 334 ? -16.490 -14.114 -64.247  1.00 31.74  ? 327  PHE C CE1 1 
ATOM   9609  C CE2 . PHE C 1 334 ? -16.637 -16.015 -62.814  1.00 32.48  ? 327  PHE C CE2 1 
ATOM   9610  C CZ  . PHE C 1 334 ? -16.905 -15.406 -64.028  1.00 32.28  ? 327  PHE C CZ  1 
ATOM   9611  N N   . LEU C 1 335 ? -11.315 -12.994 -59.975  1.00 23.06  ? 328  LEU C N   1 
ATOM   9612  C CA  . LEU C 1 335 ? -10.442 -12.350 -58.981  1.00 22.94  ? 328  LEU C CA  1 
ATOM   9613  C C   . LEU C 1 335 ? -9.987  -10.983 -59.510  1.00 20.76  ? 328  LEU C C   1 
ATOM   9614  O O   . LEU C 1 335 ? -9.942  -10.005 -58.738  1.00 19.67  ? 328  LEU C O   1 
ATOM   9615  C CB  . LEU C 1 335 ? -9.275  -13.305 -58.738  1.00 25.13  ? 328  LEU C CB  1 
ATOM   9616  C CG  . LEU C 1 335 ? -8.536  -13.115 -57.422  1.00 26.79  ? 328  LEU C CG  1 
ATOM   9617  C CD1 . LEU C 1 335 ? -9.513  -12.982 -56.271  1.00 27.18  ? 328  LEU C CD1 1 
ATOM   9618  C CD2 . LEU C 1 335 ? -7.577  -14.264 -57.176  1.00 27.69  ? 328  LEU C CD2 1 
ATOM   9619  N N   . HIS C 1 336 ? -9.616  -10.944 -60.786  1.00 20.10  ? 329  HIS C N   1 
ATOM   9620  C CA  . HIS C 1 336 ? -9.283  -9.702  -61.527  1.00 20.84  ? 329  HIS C CA  1 
ATOM   9621  C C   . HIS C 1 336 ? -10.077 -9.700  -62.835  1.00 24.06  ? 329  HIS C C   1 
ATOM   9622  O O   . HIS C 1 336 ? -9.972  -10.676 -63.606  1.00 26.09  ? 329  HIS C O   1 
ATOM   9623  C CB  . HIS C 1 336 ? -7.768  -9.534  -61.763  1.00 18.50  ? 329  HIS C CB  1 
ATOM   9624  C CG  . HIS C 1 336 ? -7.413  -8.162  -62.239  1.00 17.70  ? 329  HIS C CG  1 
ATOM   9625  N ND1 . HIS C 1 336 ? -7.716  -7.031  -61.519  1.00 16.91  ? 329  HIS C ND1 1 
ATOM   9626  C CD2 . HIS C 1 336 ? -6.802  -7.727  -63.363  1.00 18.40  ? 329  HIS C CD2 1 
ATOM   9627  C CE1 . HIS C 1 336 ? -7.321  -5.959  -62.167  1.00 17.78  ? 329  HIS C CE1 1 
ATOM   9628  N NE2 . HIS C 1 336 ? -6.731  -6.358  -63.301  1.00 18.27  ? 329  HIS C NE2 1 
ATOM   9629  N N   . THR C 1 337 ? -10.835 -8.625  -63.041  1.00 26.20  ? 330  THR C N   1 
ATOM   9630  C CA  . THR C 1 337 ? -11.680 -8.389  -64.230  1.00 27.21  ? 330  THR C CA  1 
ATOM   9631  C C   . THR C 1 337 ? -11.681 -6.898  -64.561  1.00 28.36  ? 330  THR C C   1 
ATOM   9632  O O   . THR C 1 337 ? -11.235 -6.083  -63.720  1.00 28.51  ? 330  THR C O   1 
ATOM   9633  C CB  . THR C 1 337 ? -13.095 -8.921  -64.000  1.00 28.22  ? 330  THR C CB  1 
ATOM   9634  O OG1 . THR C 1 337 ? -13.714 -8.218  -62.917  1.00 26.19  ? 330  THR C OG1 1 
ATOM   9635  C CG2 . THR C 1 337 ? -13.071 -10.411 -63.739  1.00 29.05  ? 330  THR C CG2 1 
ATOM   9636  N N   . THR C 1 338 ? -12.150 -6.584  -65.768  1.00 28.56  ? 331  THR C N   1 
ATOM   9637  C CA  . THR C 1 338 ? -12.517 -5.217  -66.213  1.00 28.82  ? 331  THR C CA  1 
ATOM   9638  C C   . THR C 1 338 ? -13.689 -5.430  -67.170  1.00 27.68  ? 331  THR C C   1 
ATOM   9639  O O   . THR C 1 338 ? -13.824 -6.565  -67.688  1.00 32.16  ? 331  THR C O   1 
ATOM   9640  C CB  . THR C 1 338 ? -11.278 -4.481  -66.749  1.00 28.19  ? 331  THR C CB  1 
ATOM   9641  O OG1 . THR C 1 338 ? -11.477 -3.063  -66.671  1.00 30.07  ? 331  THR C OG1 1 
ATOM   9642  C CG2 . THR C 1 338 ? -10.916 -4.904  -68.159  1.00 26.53  ? 331  THR C CG2 1 
ATOM   9643  N N   A THR C 1 339 ? -14.513 -4.410  -67.390  0.50 26.88  ? 332  THR C N   1 
ATOM   9644  N N   B THR C 1 339 ? -14.524 -4.415  -67.375  0.50 26.41  ? 332  THR C N   1 
ATOM   9645  C CA  A THR C 1 339 ? -15.721 -4.525  -68.255  0.50 26.27  ? 332  THR C CA  1 
ATOM   9646  C CA  B THR C 1 339 ? -15.727 -4.516  -68.245  0.50 25.61  ? 332  THR C CA  1 
ATOM   9647  C C   A THR C 1 339 ? -15.298 -4.488  -69.731  0.50 23.85  ? 332  THR C C   1 
ATOM   9648  C C   B THR C 1 339 ? -15.301 -4.488  -69.723  0.50 23.49  ? 332  THR C C   1 
ATOM   9649  O O   A THR C 1 339 ? -15.709 -5.394  -70.480  0.50 24.25  ? 332  THR C O   1 
ATOM   9650  O O   B THR C 1 339 ? -15.718 -5.390  -70.471  0.50 23.89  ? 332  THR C O   1 
ATOM   9651  C CB  A THR C 1 339 ? -16.765 -3.480  -67.855  0.50 27.54  ? 332  THR C CB  1 
ATOM   9652  C CB  B THR C 1 339 ? -16.753 -3.439  -67.872  0.50 26.29  ? 332  THR C CB  1 
ATOM   9653  O OG1 A THR C 1 339 ? -16.116 -2.211  -67.845  0.50 28.65  ? 332  THR C OG1 1 
ATOM   9654  O OG1 B THR C 1 339 ? -17.308 -3.773  -66.600  0.50 28.41  ? 332  THR C OG1 1 
ATOM   9655  C CG2 A THR C 1 339 ? -17.331 -3.753  -66.482  0.50 28.68  ? 332  THR C CG2 1 
ATOM   9656  C CG2 B THR C 1 339 ? -17.871 -3.328  -68.878  0.50 26.04  ? 332  THR C CG2 1 
ATOM   9657  N N   . PHE C 1 340 ? -14.478 -3.514  -70.119  1.00 20.98  ? 333  PHE C N   1 
ATOM   9658  C CA  . PHE C 1 340 ? -14.138 -3.256  -71.542  1.00 20.11  ? 333  PHE C CA  1 
ATOM   9659  C C   . PHE C 1 340 ? -12.902 -4.035  -72.018  1.00 18.95  ? 333  PHE C C   1 
ATOM   9660  O O   . PHE C 1 340 ? -12.662 -4.058  -73.208  1.00 19.56  ? 333  PHE C O   1 
ATOM   9661  C CB  . PHE C 1 340 ? -13.883 -1.762  -71.735  1.00 19.60  ? 333  PHE C CB  1 
ATOM   9662  C CG  . PHE C 1 340 ? -15.050 -0.851  -71.450  1.00 18.66  ? 333  PHE C CG  1 
ATOM   9663  C CD1 . PHE C 1 340 ? -16.294 -1.067  -72.025  1.00 18.82  ? 333  PHE C CD1 1 
ATOM   9664  C CD2 . PHE C 1 340 ? -14.893 0.251   -70.627  1.00 18.03  ? 333  PHE C CD2 1 
ATOM   9665  C CE1 . PHE C 1 340 ? -17.359 -0.219  -71.766  1.00 17.42  ? 333  PHE C CE1 1 
ATOM   9666  C CE2 . PHE C 1 340 ? -15.948 1.118   -70.391  1.00 18.21  ? 333  PHE C CE2 1 
ATOM   9667  C CZ  . PHE C 1 340 ? -17.182 0.879   -70.963  1.00 17.94  ? 333  PHE C CZ  1 
ATOM   9668  N N   . GLY C 1 341 ? -12.124 -4.638  -71.128  1.00 18.79  ? 334  GLY C N   1 
ATOM   9669  C CA  . GLY C 1 341 ? -10.792 -5.188  -71.438  1.00 17.95  ? 334  GLY C CA  1 
ATOM   9670  C C   . GLY C 1 341 ? -10.873 -6.376  -72.372  1.00 16.73  ? 334  GLY C C   1 
ATOM   9671  O O   . GLY C 1 341 ? -11.678 -7.257  -72.128  1.00 17.23  ? 334  GLY C O   1 
ATOM   9672  N N   . GLY C 1 342 ? -10.054 -6.404  -73.408  1.00 16.60  ? 335  GLY C N   1 
ATOM   9673  C CA  . GLY C 1 342 ? -10.060 -7.485  -74.408  1.00 17.99  ? 335  GLY C CA  1 
ATOM   9674  C C   . GLY C 1 342 ? -11.289 -7.418  -75.300  1.00 19.84  ? 335  GLY C C   1 
ATOM   9675  O O   . GLY C 1 342 ? -11.640 -8.458  -75.895  1.00 22.86  ? 335  GLY C O   1 
ATOM   9676  N N   . ASN C 1 343 ? -11.910 -6.239  -75.429  1.00 19.31  ? 336  ASN C N   1 
ATOM   9677  C CA  . ASN C 1 343 ? -13.061 -6.032  -76.347  1.00 18.97  ? 336  ASN C CA  1 
ATOM   9678  C C   . ASN C 1 343 ? -12.607 -6.294  -77.778  1.00 18.52  ? 336  ASN C C   1 
ATOM   9679  O O   . ASN C 1 343 ? -11.428 -6.150  -78.127  1.00 18.41  ? 336  ASN C O   1 
ATOM   9680  C CB  . ASN C 1 343 ? -13.749 -4.672  -76.184  1.00 18.43  ? 336  ASN C CB  1 
ATOM   9681  C CG  . ASN C 1 343 ? -12.928 -3.493  -76.654  1.00 18.10  ? 336  ASN C CG  1 
ATOM   9682  O OD1 . ASN C 1 343 ? -12.857 -3.208  -77.852  1.00 16.71  ? 336  ASN C OD1 1 
ATOM   9683  N ND2 . ASN C 1 343 ? -12.325 -2.788  -75.705  1.00 18.25  ? 336  ASN C ND2 1 
ATOM   9684  N N   . PRO C 1 344 ? -13.541 -6.761  -78.629  1.00 18.12  ? 337  PRO C N   1 
ATOM   9685  C CA  . PRO C 1 344 ? -13.238 -7.051  -80.027  1.00 18.02  ? 337  PRO C CA  1 
ATOM   9686  C C   . PRO C 1 344 ? -12.604 -5.929  -80.873  1.00 18.07  ? 337  PRO C C   1 
ATOM   9687  O O   . PRO C 1 344 ? -11.733 -6.262  -81.636  1.00 17.93  ? 337  PRO C O   1 
ATOM   9688  C CB  . PRO C 1 344 ? -14.616 -7.419  -80.575  1.00 18.27  ? 337  PRO C CB  1 
ATOM   9689  C CG  . PRO C 1 344 ? -15.355 -7.999  -79.397  1.00 18.24  ? 337  PRO C CG  1 
ATOM   9690  C CD  . PRO C 1 344 ? -14.908 -7.135  -78.247  1.00 18.43  ? 337  PRO C CD  1 
ATOM   9691  N N   . LEU C 1 345 ? -13.037 -4.665  -80.763  1.00 18.54  ? 338  LEU C N   1 
ATOM   9692  C CA  . LEU C 1 345 ? -12.389 -3.533  -81.496  1.00 18.48  ? 338  LEU C CA  1 
ATOM   9693  C C   . LEU C 1 345 ? -10.923 -3.468  -81.090  1.00 19.00  ? 338  LEU C C   1 
ATOM   9694  O O   . LEU C 1 345 ? -10.051 -3.414  -81.959  1.00 18.73  ? 338  LEU C O   1 
ATOM   9695  C CB  . LEU C 1 345 ? -13.027 -2.189  -81.147  1.00 20.04  ? 338  LEU C CB  1 
ATOM   9696  C CG  . LEU C 1 345 ? -14.395 -1.888  -81.768  1.00 21.93  ? 338  LEU C CG  1 
ATOM   9697  C CD1 . LEU C 1 345 ? -14.664 -0.391  -81.684  1.00 23.25  ? 338  LEU C CD1 1 
ATOM   9698  C CD2 . LEU C 1 345 ? -14.498 -2.351  -83.218  1.00 21.23  ? 338  LEU C CD2 1 
ATOM   9699  N N   . ALA C 1 346 ? -10.662 -3.424  -79.793  1.00 18.89  ? 339  ALA C N   1 
ATOM   9700  C CA  . ALA C 1 346 ? -9.292  -3.293  -79.288  1.00 19.29  ? 339  ALA C CA  1 
ATOM   9701  C C   . ALA C 1 346 ? -8.475  -4.481  -79.798  1.00 19.80  ? 339  ALA C C   1 
ATOM   9702  O O   . ALA C 1 346 ? -7.367  -4.222  -80.279  1.00 20.73  ? 339  ALA C O   1 
ATOM   9703  C CB  . ALA C 1 346 ? -9.288  -3.191  -77.788  1.00 20.40  ? 339  ALA C CB  1 
ATOM   9704  N N   . CYS C 1 347 ? -8.987  -5.718  -79.701  1.00 20.31  ? 340  CYS C N   1 
ATOM   9705  C CA  . CYS C 1 347 ? -8.256  -6.958  -80.103  1.00 20.69  ? 340  CYS C CA  1 
ATOM   9706  C C   . CYS C 1 347 ? -7.961  -6.906  -81.611  1.00 20.65  ? 340  CYS C C   1 
ATOM   9707  O O   . CYS C 1 347 ? -6.785  -7.148  -82.023  1.00 21.79  ? 340  CYS C O   1 
ATOM   9708  C CB  . CYS C 1 347 ? -9.033  -8.233  -79.797  1.00 21.47  ? 340  CYS C CB  1 
ATOM   9709  S SG  . CYS C 1 347 ? -9.077  -8.654  -78.037  1.00 22.88  ? 340  CYS C SG  1 
ATOM   9710  N N   . ALA C 1 348 ? -8.974  -6.573  -82.403  1.00 18.75  ? 341  ALA C N   1 
ATOM   9711  C CA  . ALA C 1 348 ? -8.837  -6.346  -83.855  1.00 18.55  ? 341  ALA C CA  1 
ATOM   9712  C C   . ALA C 1 348 ? -7.679  -5.368  -84.100  1.00 18.27  ? 341  ALA C C   1 
ATOM   9713  O O   . ALA C 1 348 ? -6.829  -5.684  -84.931  1.00 19.21  ? 341  ALA C O   1 
ATOM   9714  C CB  . ALA C 1 348 ? -10.130 -5.847  -84.443  1.00 17.41  ? 341  ALA C CB  1 
ATOM   9715  N N   . ALA C 1 349 ? -7.641  -4.238  -83.390  1.00 17.98  ? 342  ALA C N   1 
ATOM   9716  C CA  . ALA C 1 349 ? -6.645  -3.155  -83.594  1.00 16.98  ? 342  ALA C CA  1 
ATOM   9717  C C   . ALA C 1 349 ? -5.249  -3.692  -83.268  1.00 16.17  ? 342  ALA C C   1 
ATOM   9718  O O   . ALA C 1 349 ? -4.310  -3.435  -84.040  1.00 16.70  ? 342  ALA C O   1 
ATOM   9719  C CB  . ALA C 1 349 ? -6.982  -1.955  -82.741  1.00 16.85  ? 342  ALA C CB  1 
ATOM   9720  N N   . ALA C 1 350 ? -5.125  -4.440  -82.171  1.00 15.65  ? 343  ALA C N   1 
ATOM   9721  C CA  . ALA C 1 350 ? -3.838  -5.014  -81.720  1.00 15.25  ? 343  ALA C CA  1 
ATOM   9722  C C   . ALA C 1 350 ? -3.389  -6.079  -82.730  1.00 14.98  ? 343  ALA C C   1 
ATOM   9723  O O   . ALA C 1 350 ? -2.190  -6.091  -83.049  1.00 15.16  ? 343  ALA C O   1 
ATOM   9724  C CB  . ALA C 1 350 ? -3.939  -5.575  -80.334  1.00 14.12  ? 343  ALA C CB  1 
ATOM   9725  N N   . LEU C 1 351 ? -4.310  -6.932  -83.202  1.00 14.65  ? 344  LEU C N   1 
ATOM   9726  C CA  . LEU C 1 351 ? -3.960  -8.064  -84.083  1.00 14.37  ? 344  LEU C CA  1 
ATOM   9727  C C   . LEU C 1 351 ? -3.445  -7.482  -85.390  1.00 16.93  ? 344  LEU C C   1 
ATOM   9728  O O   . LEU C 1 351 ? -2.416  -7.997  -85.920  1.00 19.32  ? 344  LEU C O   1 
ATOM   9729  C CB  . LEU C 1 351 ? -5.184  -8.933  -84.309  1.00 13.75  ? 344  LEU C CB  1 
ATOM   9730  C CG  . LEU C 1 351 ? -5.540  -9.858  -83.154  1.00 13.17  ? 344  LEU C CG  1 
ATOM   9731  C CD1 . LEU C 1 351 ? -7.014  -10.261 -83.196  1.00 12.55  ? 344  LEU C CD1 1 
ATOM   9732  C CD2 . LEU C 1 351 ? -4.637  -11.076 -83.194  1.00 13.13  ? 344  LEU C CD2 1 
ATOM   9733  N N   . ALA C 1 352 ? -4.100  -6.418  -85.863  1.00 16.98  ? 345  ALA C N   1 
ATOM   9734  C CA  . ALA C 1 352 ? -3.684  -5.658  -87.061  1.00 17.59  ? 345  ALA C CA  1 
ATOM   9735  C C   . ALA C 1 352 ? -2.279  -5.095  -86.827  1.00 18.17  ? 345  ALA C C   1 
ATOM   9736  O O   . ALA C 1 352 ? -1.432  -5.261  -87.702  1.00 19.24  ? 345  ALA C O   1 
ATOM   9737  C CB  . ALA C 1 352 ? -4.665  -4.554  -87.361  1.00 17.65  ? 345  ALA C CB  1 
ATOM   9738  N N   . THR C 1 353 ? -2.057  -4.452  -85.680  1.00 17.69  ? 346  THR C N   1 
ATOM   9739  C CA  . THR C 1 353 ? -0.798  -3.753  -85.348  1.00 18.38  ? 346  THR C CA  1 
ATOM   9740  C C   . THR C 1 353 ? 0.357   -4.746  -85.402  1.00 18.80  ? 346  THR C C   1 
ATOM   9741  O O   . THR C 1 353 ? 1.359   -4.424  -86.054  1.00 20.16  ? 346  THR C O   1 
ATOM   9742  C CB  . THR C 1 353 ? -0.880  -3.088  -83.973  1.00 19.34  ? 346  THR C CB  1 
ATOM   9743  O OG1 . THR C 1 353 ? -2.034  -2.248  -84.007  1.00 19.85  ? 346  THR C OG1 1 
ATOM   9744  C CG2 . THR C 1 353 ? 0.373   -2.305  -83.645  1.00 18.68  ? 346  THR C CG2 1 
ATOM   9745  N N   . ILE C 1 354 ? 0.215   -5.898  -84.745  1.00 19.03  ? 347  ILE C N   1 
ATOM   9746  C CA  . ILE C 1 354 ? 1.244   -6.977  -84.768  1.00 19.14  ? 347  ILE C CA  1 
ATOM   9747  C C   . ILE C 1 354 ? 1.463   -7.414  -86.213  1.00 19.61  ? 347  ILE C C   1 
ATOM   9748  O O   . ILE C 1 354 ? 2.636   -7.550  -86.627  1.00 19.71  ? 347  ILE C O   1 
ATOM   9749  C CB  . ILE C 1 354 ? 0.811   -8.176  -83.920  1.00 20.67  ? 347  ILE C CB  1 
ATOM   9750  C CG1 . ILE C 1 354 ? 0.856   -7.835  -82.432  1.00 21.19  ? 347  ILE C CG1 1 
ATOM   9751  C CG2 . ILE C 1 354 ? 1.642   -9.412  -84.248  1.00 20.06  ? 347  ILE C CG2 1 
ATOM   9752  C CD1 . ILE C 1 354 ? -0.068  -8.693  -81.600  1.00 21.76  ? 347  ILE C CD1 1 
ATOM   9753  N N   . ASN C 1 355 ? 0.385   -7.657  -86.954  1.00 17.72  ? 348  ASN C N   1 
ATOM   9754  C CA  . ASN C 1 355 ? 0.512   -8.087  -88.361  1.00 18.05  ? 348  ASN C CA  1 
ATOM   9755  C C   . ASN C 1 355 ? 1.349   -7.063  -89.144  1.00 17.11  ? 348  ASN C C   1 
ATOM   9756  O O   . ASN C 1 355 ? 2.229   -7.499  -89.882  1.00 15.02  ? 348  ASN C O   1 
ATOM   9757  C CB  . ASN C 1 355 ? -0.846  -8.286  -89.025  1.00 18.90  ? 348  ASN C CB  1 
ATOM   9758  C CG  . ASN C 1 355 ? -0.696  -8.961  -90.356  1.00 18.55  ? 348  ASN C CG  1 
ATOM   9759  O OD1 . ASN C 1 355 ? -0.723  -8.297  -91.381  1.00 21.55  ? 348  ASN C OD1 1 
ATOM   9760  N ND2 . ASN C 1 355 ? -0.468  -10.261 -90.329  1.00 18.57  ? 348  ASN C ND2 1 
ATOM   9761  N N   . VAL C 1 356 ? 1.077   -5.765  -88.967  1.00 16.66  ? 349  VAL C N   1 
ATOM   9762  C CA  . VAL C 1 356 ? 1.757   -4.649  -89.696  1.00 16.33  ? 349  VAL C CA  1 
ATOM   9763  C C   . VAL C 1 356 ? 3.239   -4.623  -89.302  1.00 16.68  ? 349  VAL C C   1 
ATOM   9764  O O   . VAL C 1 356 ? 4.070   -4.573  -90.186  1.00 15.74  ? 349  VAL C O   1 
ATOM   9765  C CB  . VAL C 1 356 ? 1.092   -3.287  -89.410  1.00 15.54  ? 349  VAL C CB  1 
ATOM   9766  C CG1 . VAL C 1 356 ? 1.964   -2.098  -89.812  1.00 14.85  ? 349  VAL C CG1 1 
ATOM   9767  C CG2 . VAL C 1 356 ? -0.255  -3.196  -90.077  1.00 15.39  ? 349  VAL C CG2 1 
ATOM   9768  N N   . LEU C 1 357 ? 3.552   -4.640  -88.002  1.00 17.66  ? 350  LEU C N   1 
ATOM   9769  C CA  . LEU C 1 357 ? 4.944   -4.503  -87.516  1.00 18.41  ? 350  LEU C CA  1 
ATOM   9770  C C   . LEU C 1 357 ? 5.795   -5.639  -88.088  1.00 19.11  ? 350  LEU C C   1 
ATOM   9771  O O   . LEU C 1 357 ? 6.938   -5.364  -88.481  1.00 19.60  ? 350  LEU C O   1 
ATOM   9772  C CB  . LEU C 1 357 ? 4.967   -4.516  -85.987  1.00 19.03  ? 350  LEU C CB  1 
ATOM   9773  C CG  . LEU C 1 357 ? 4.409   -3.265  -85.307  1.00 19.49  ? 350  LEU C CG  1 
ATOM   9774  C CD1 . LEU C 1 357 ? 4.151   -3.536  -83.826  1.00 19.75  ? 350  LEU C CD1 1 
ATOM   9775  C CD2 . LEU C 1 357 ? 5.334   -2.068  -85.462  1.00 19.20  ? 350  LEU C CD2 1 
ATOM   9776  N N   . LEU C 1 358 ? 5.256   -6.861  -88.121  1.00 20.24  ? 351  LEU C N   1 
ATOM   9777  C CA  . LEU C 1 358 ? 5.995   -8.066  -88.578  1.00 22.91  ? 351  LEU C CA  1 
ATOM   9778  C C   . LEU C 1 358 ? 6.107   -8.063  -90.109  1.00 24.98  ? 351  LEU C C   1 
ATOM   9779  O O   . LEU C 1 358 ? 7.244   -8.195  -90.598  1.00 22.69  ? 351  LEU C O   1 
ATOM   9780  C CB  . LEU C 1 358 ? 5.305   -9.318  -88.035  1.00 22.96  ? 351  LEU C CB  1 
ATOM   9781  C CG  . LEU C 1 358 ? 5.392   -9.475  -86.514  1.00 24.68  ? 351  LEU C CG  1 
ATOM   9782  C CD1 . LEU C 1 358 ? 4.766   -10.776 -86.032  1.00 25.72  ? 351  LEU C CD1 1 
ATOM   9783  C CD2 . LEU C 1 358 ? 6.828   -9.397  -86.043  1.00 25.90  ? 351  LEU C CD2 1 
ATOM   9784  N N   . GLU C 1 359 ? 4.982   -7.894  -90.825  1.00 28.54  ? 352  GLU C N   1 
ATOM   9785  C CA  . GLU C 1 359 ? 4.912   -7.834  -92.323  1.00 30.94  ? 352  GLU C CA  1 
ATOM   9786  C C   . GLU C 1 359 ? 5.950   -6.857  -92.874  1.00 26.52  ? 352  GLU C C   1 
ATOM   9787  O O   . GLU C 1 359 ? 6.591   -7.227  -93.841  1.00 25.63  ? 352  GLU C O   1 
ATOM   9788  C CB  . GLU C 1 359 ? 3.575   -7.298  -92.848  1.00 36.85  ? 352  GLU C CB  1 
ATOM   9789  C CG  . GLU C 1 359 ? 2.502   -8.351  -93.033  1.00 43.09  ? 352  GLU C CG  1 
ATOM   9790  C CD  . GLU C 1 359 ? 2.468   -8.985  -94.408  1.00 49.03  ? 352  GLU C CD  1 
ATOM   9791  O OE1 . GLU C 1 359 ? 3.561   -9.376  -94.911  1.00 51.83  ? 352  GLU C OE1 1 
ATOM   9792  O OE2 . GLU C 1 359 ? 1.335   -9.088  -94.980  1.00 56.47  ? 352  GLU C OE2 1 
ATOM   9793  N N   . GLN C 1 360 ? 6.038   -5.648  -92.313  1.00 24.37  ? 353  GLN C N   1 
ATOM   9794  C CA  . GLN C 1 360 ? 6.861   -4.532  -92.847  1.00 24.50  ? 353  GLN C CA  1 
ATOM   9795  C C   . GLN C 1 360 ? 8.205   -4.388  -92.129  1.00 23.77  ? 353  GLN C C   1 
ATOM   9796  O O   . GLN C 1 360 ? 8.920   -3.439  -92.447  1.00 22.93  ? 353  GLN C O   1 
ATOM   9797  C CB  . GLN C 1 360 ? 6.133   -3.205  -92.710  1.00 25.49  ? 353  GLN C CB  1 
ATOM   9798  C CG  . GLN C 1 360 ? 4.766   -3.188  -93.365  1.00 26.26  ? 353  GLN C CG  1 
ATOM   9799  C CD  . GLN C 1 360 ? 4.293   -1.765  -93.495  1.00 28.54  ? 353  GLN C CD  1 
ATOM   9800  O OE1 . GLN C 1 360 ? 5.085   -0.884  -93.830  1.00 29.45  ? 353  GLN C OE1 1 
ATOM   9801  N NE2 . GLN C 1 360 ? 3.005   -1.537  -93.249  1.00 29.92  ? 353  GLN C NE2 1 
ATOM   9802  N N   A ASN C 1 361 ? 8.531   -5.294  -91.201  0.54 24.43  ? 354  ASN C N   1 
ATOM   9803  N N   B ASN C 1 361 ? 8.529   -5.285  -91.192  0.46 24.66  ? 354  ASN C N   1 
ATOM   9804  C CA  A ASN C 1 361 ? 9.786   -5.271  -90.395  0.54 23.23  ? 354  ASN C CA  1 
ATOM   9805  C CA  B ASN C 1 361 ? 9.826   -5.270  -90.456  0.46 23.84  ? 354  ASN C CA  1 
ATOM   9806  C C   A ASN C 1 361 ? 10.056  -3.860  -89.859  0.54 21.97  ? 354  ASN C C   1 
ATOM   9807  C C   B ASN C 1 361 ? 10.068  -3.867  -89.859  0.46 22.41  ? 354  ASN C C   1 
ATOM   9808  O O   A ASN C 1 361 ? 11.190  -3.384  -89.947  0.54 23.10  ? 354  ASN C O   1 
ATOM   9809  O O   B ASN C 1 361 ? 11.193  -3.376  -89.947  0.46 23.37  ? 354  ASN C O   1 
ATOM   9810  C CB  A ASN C 1 361 ? 11.005  -5.784  -91.154  0.54 23.34  ? 354  ASN C CB  1 
ATOM   9811  C CB  B ASN C 1 361 ? 10.970  -5.705  -91.388  0.46 24.23  ? 354  ASN C CB  1 
ATOM   9812  C CG  A ASN C 1 361 ? 12.068  -6.272  -90.179  0.54 22.73  ? 354  ASN C CG  1 
ATOM   9813  C CG  B ASN C 1 361 ? 10.704  -6.993  -92.150  0.46 24.34  ? 354  ASN C CG  1 
ATOM   9814  O OD1 A ASN C 1 361 ? 12.010  -5.979  -88.977  0.54 23.44  ? 354  ASN C OD1 1 
ATOM   9815  O OD1 B ASN C 1 361 ? 10.746  -8.085  -91.588  0.46 25.19  ? 354  ASN C OD1 1 
ATOM   9816  N ND2 A ASN C 1 361 ? 13.030  -7.034  -90.666  0.54 21.67  ? 354  ASN C ND2 1 
ATOM   9817  N ND2 B ASN C 1 361 ? 10.459  -6.893  -93.445  0.46 25.54  ? 354  ASN C ND2 1 
ATOM   9818  N N   . LEU C 1 362 ? 9.051   -3.232  -89.272  1.00 22.32  ? 355  LEU C N   1 
ATOM   9819  C CA  . LEU C 1 362 ? 9.166   -1.856  -88.713  1.00 22.41  ? 355  LEU C CA  1 
ATOM   9820  C C   . LEU C 1 362 ? 10.119  -1.804  -87.515  1.00 21.13  ? 355  LEU C C   1 
ATOM   9821  O O   . LEU C 1 362 ? 10.708  -0.752  -87.270  1.00 20.32  ? 355  LEU C O   1 
ATOM   9822  C CB  . LEU C 1 362 ? 7.768   -1.345  -88.337  1.00 22.89  ? 355  LEU C CB  1 
ATOM   9823  C CG  . LEU C 1 362 ? 7.011   -0.693  -89.488  1.00 22.77  ? 355  LEU C CG  1 
ATOM   9824  C CD1 . LEU C 1 362 ? 5.518   -0.604  -89.181  1.00 22.94  ? 355  LEU C CD1 1 
ATOM   9825  C CD2 . LEU C 1 362 ? 7.583   0.681   -89.816  1.00 22.37  ? 355  LEU C CD2 1 
ATOM   9826  N N   . PRO C 1 363 ? 10.305  -2.882  -86.715  1.00 20.96  ? 356  PRO C N   1 
ATOM   9827  C CA  . PRO C 1 363 ? 11.371  -2.891  -85.707  1.00 22.74  ? 356  PRO C CA  1 
ATOM   9828  C C   . PRO C 1 363 ? 12.730  -2.579  -86.354  1.00 21.56  ? 356  PRO C C   1 
ATOM   9829  O O   . PRO C 1 363 ? 13.419  -1.661  -85.904  1.00 20.62  ? 356  PRO C O   1 
ATOM   9830  C CB  . PRO C 1 363 ? 11.302  -4.297  -85.079  1.00 22.00  ? 356  PRO C CB  1 
ATOM   9831  C CG  . PRO C 1 363 ? 9.836   -4.661  -85.260  1.00 21.33  ? 356  PRO C CG  1 
ATOM   9832  C CD  . PRO C 1 363 ? 9.468   -4.087  -86.621  1.00 21.66  ? 356  PRO C CD  1 
ATOM   9833  N N   . ALA C 1 364 ? 13.059  -3.290  -87.428  1.00 19.91  ? 357  ALA C N   1 
ATOM   9834  C CA  . ALA C 1 364 ? 14.311  -3.035  -88.160  1.00 20.23  ? 357  ALA C CA  1 
ATOM   9835  C C   . ALA C 1 364 ? 14.347  -1.576  -88.649  1.00 20.20  ? 357  ALA C C   1 
ATOM   9836  O O   . ALA C 1 364 ? 15.430  -0.959  -88.582  1.00 19.44  ? 357  ALA C O   1 
ATOM   9837  C CB  . ALA C 1 364 ? 14.436  -4.033  -89.266  1.00 21.32  ? 357  ALA C CB  1 
ATOM   9838  N N   . GLN C 1 365 ? 13.224  -1.015  -89.106  1.00 20.23  ? 358  GLN C N   1 
ATOM   9839  C CA  . GLN C 1 365 ? 13.189  0.379   -89.634  1.00 20.97  ? 358  GLN C CA  1 
ATOM   9840  C C   . GLN C 1 365 ? 13.497  1.352   -88.498  1.00 19.86  ? 358  GLN C C   1 
ATOM   9841  O O   . GLN C 1 365 ? 14.229  2.334   -88.715  1.00 19.18  ? 358  GLN C O   1 
ATOM   9842  C CB  . GLN C 1 365 ? 11.840  0.711   -90.269  1.00 22.58  ? 358  GLN C CB  1 
ATOM   9843  C CG  . GLN C 1 365 ? 11.607  -0.035  -91.565  1.00 25.18  ? 358  GLN C CG  1 
ATOM   9844  C CD  . GLN C 1 365 ? 10.363  0.420   -92.281  1.00 28.98  ? 358  GLN C CD  1 
ATOM   9845  O OE1 . GLN C 1 365 ? 10.127  1.612   -92.472  1.00 33.79  ? 358  GLN C OE1 1 
ATOM   9846  N NE2 . GLN C 1 365 ? 9.543   -0.540  -92.676  1.00 30.87  ? 358  GLN C NE2 1 
ATOM   9847  N N   . ALA C 1 366 ? 12.932  1.089   -87.329  1.00 20.00  ? 359  ALA C N   1 
ATOM   9848  C CA  . ALA C 1 366 ? 13.084  1.957   -86.150  1.00 20.98  ? 359  ALA C CA  1 
ATOM   9849  C C   . ALA C 1 366 ? 14.580  2.039   -85.809  1.00 21.38  ? 359  ALA C C   1 
ATOM   9850  O O   . ALA C 1 366 ? 15.084  3.154   -85.544  1.00 20.29  ? 359  ALA C O   1 
ATOM   9851  C CB  . ALA C 1 366 ? 12.252  1.429   -85.012  1.00 20.54  ? 359  ALA C CB  1 
ATOM   9852  N N   . GLU C 1 367 ? 15.261  0.893   -85.837  1.00 22.57  ? 360  GLU C N   1 
ATOM   9853  C CA  . GLU C 1 367 ? 16.722  0.796   -85.593  1.00 24.78  ? 360  GLU C CA  1 
ATOM   9854  C C   . GLU C 1 367 ? 17.463  1.734   -86.559  1.00 23.98  ? 360  GLU C C   1 
ATOM   9855  O O   . GLU C 1 367 ? 18.241  2.599   -86.078  1.00 20.64  ? 360  GLU C O   1 
ATOM   9856  C CB  . GLU C 1 367 ? 17.195  -0.649  -85.763  1.00 28.75  ? 360  GLU C CB  1 
ATOM   9857  C CG  . GLU C 1 367 ? 18.640  -0.897  -85.347  1.00 32.54  ? 360  GLU C CG  1 
ATOM   9858  C CD  . GLU C 1 367 ? 19.206  -2.222  -85.876  1.00 37.12  ? 360  GLU C CD  1 
ATOM   9859  O OE1 . GLU C 1 367 ? 18.799  -2.627  -87.016  1.00 40.73  ? 360  GLU C OE1 1 
ATOM   9860  O OE2 . GLU C 1 367 ? 20.047  -2.861  -85.166  1.00 37.04  ? 360  GLU C OE2 1 
ATOM   9861  N N   A GLN C 1 368 ? 17.218  1.575   -87.867  0.25 22.70  ? 361  GLN C N   1 
ATOM   9862  N N   B GLN C 1 368 ? 17.227  1.574   -87.869  0.25 22.75  ? 361  GLN C N   1 
ATOM   9863  N N   C GLN C 1 368 ? 17.223  1.576   -87.870  0.50 23.14  ? 361  GLN C N   1 
ATOM   9864  C CA  A GLN C 1 368 ? 17.956  2.306   -88.926  0.25 21.96  ? 361  GLN C CA  1 
ATOM   9865  C CA  B GLN C 1 368 ? 17.962  2.310   -88.929  0.25 22.04  ? 361  GLN C CA  1 
ATOM   9866  C CA  C GLN C 1 368 ? 17.956  2.309   -88.930  0.50 22.36  ? 361  GLN C CA  1 
ATOM   9867  C C   A GLN C 1 368 ? 17.661  3.797   -88.787  0.25 20.88  ? 361  GLN C C   1 
ATOM   9868  C C   B GLN C 1 368 ? 17.662  3.801   -88.787  0.25 20.93  ? 361  GLN C C   1 
ATOM   9869  C C   C GLN C 1 368 ? 17.658  3.800   -88.786  0.50 20.73  ? 361  GLN C C   1 
ATOM   9870  O O   A GLN C 1 368 ? 18.611  4.586   -88.787  0.25 20.70  ? 361  GLN C O   1 
ATOM   9871  O O   B GLN C 1 368 ? 18.611  4.595   -88.783  0.25 20.74  ? 361  GLN C O   1 
ATOM   9872  O O   C GLN C 1 368 ? 18.604  4.592   -88.779  0.50 20.47  ? 361  GLN C O   1 
ATOM   9873  C CB  A GLN C 1 368 ? 17.575  1.827   -90.327  0.25 22.71  ? 361  GLN C CB  1 
ATOM   9874  C CB  B GLN C 1 368 ? 17.578  1.825   -90.328  0.25 22.86  ? 361  GLN C CB  1 
ATOM   9875  C CB  C GLN C 1 368 ? 17.560  1.811   -90.320  0.50 24.25  ? 361  GLN C CB  1 
ATOM   9876  C CG  A GLN C 1 368 ? 18.597  2.219   -91.387  0.25 23.16  ? 361  GLN C CG  1 
ATOM   9877  C CG  B GLN C 1 368 ? 18.603  2.190   -91.400  0.25 23.37  ? 361  GLN C CG  1 
ATOM   9878  C CG  C GLN C 1 368 ? 18.401  0.649   -90.826  0.50 25.21  ? 361  GLN C CG  1 
ATOM   9879  C CD  A GLN C 1 368 ? 18.160  3.327   -92.319  0.25 23.45  ? 361  GLN C CD  1 
ATOM   9880  C CD  B GLN C 1 368 ? 18.317  3.483   -92.130  0.25 23.71  ? 361  GLN C CD  1 
ATOM   9881  C CD  C GLN C 1 368 ? 17.833  0.053   -92.092  0.50 27.04  ? 361  GLN C CD  1 
ATOM   9882  O OE1 A GLN C 1 368 ? 17.570  4.322   -91.905  0.25 23.42  ? 361  GLN C OE1 1 
ATOM   9883  O OE1 B GLN C 1 368 ? 17.436  4.257   -91.758  0.25 23.82  ? 361  GLN C OE1 1 
ATOM   9884  O OE1 C GLN C 1 368 ? 17.736  0.709   -93.135  0.50 27.49  ? 361  GLN C OE1 1 
ATOM   9885  N NE2 A GLN C 1 368 ? 18.462  3.163   -93.597  0.25 23.40  ? 361  GLN C NE2 1 
ATOM   9886  N NE2 B GLN C 1 368 ? 19.057  3.716   -93.205  0.25 23.75  ? 361  GLN C NE2 1 
ATOM   9887  N NE2 C GLN C 1 368 ? 17.438  -1.208  -92.008  0.50 27.89  ? 361  GLN C NE2 1 
ATOM   9888  N N   . LYS C 1 369 ? 16.384  4.152   -88.661  1.00 19.90  ? 362  LYS C N   1 
ATOM   9889  C CA  . LYS C 1 369 ? 15.942  5.563   -88.682  1.00 21.21  ? 362  LYS C CA  1 
ATOM   9890  C C   . LYS C 1 369 ? 16.347  6.252   -87.377  1.00 21.71  ? 362  LYS C C   1 
ATOM   9891  O O   . LYS C 1 369 ? 16.718  7.430   -87.423  1.00 21.03  ? 362  LYS C O   1 
ATOM   9892  C CB  . LYS C 1 369 ? 14.432  5.626   -88.914  1.00 22.28  ? 362  LYS C CB  1 
ATOM   9893  C CG  . LYS C 1 369 ? 14.005  5.207   -90.311  1.00 23.05  ? 362  LYS C CG  1 
ATOM   9894  C CD  . LYS C 1 369 ? 12.516  4.946   -90.433  1.00 23.09  ? 362  LYS C CD  1 
ATOM   9895  C CE  . LYS C 1 369 ? 12.117  4.432   -91.791  1.00 22.97  ? 362  LYS C CE  1 
ATOM   9896  N NZ  . LYS C 1 369 ? 10.644  4.425   -91.936  1.00 25.42  ? 362  LYS C NZ  1 
ATOM   9897  N N   . GLY C 1 370 ? 16.273  5.533   -86.259  1.00 23.22  ? 363  GLY C N   1 
ATOM   9898  C CA  . GLY C 1 370 ? 16.734  6.021   -84.952  1.00 23.18  ? 363  GLY C CA  1 
ATOM   9899  C C   . GLY C 1 370 ? 18.230  6.300   -84.966  1.00 24.54  ? 363  GLY C C   1 
ATOM   9900  O O   . GLY C 1 370 ? 18.661  7.366   -84.484  1.00 23.25  ? 363  GLY C O   1 
ATOM   9901  N N   . ASP C 1 371 ? 19.014  5.365   -85.498  1.00 26.45  ? 364  ASP C N   1 
ATOM   9902  C CA  . ASP C 1 371 ? 20.481  5.544   -85.651  1.00 26.35  ? 364  ASP C CA  1 
ATOM   9903  C C   . ASP C 1 371 ? 20.743  6.817   -86.458  1.00 24.66  ? 364  ASP C C   1 
ATOM   9904  O O   . ASP C 1 371 ? 21.608  7.621   -86.059  1.00 21.87  ? 364  ASP C O   1 
ATOM   9905  C CB  . ASP C 1 371 ? 21.117  4.308   -86.288  1.00 29.00  ? 364  ASP C CB  1 
ATOM   9906  C CG  . ASP C 1 371 ? 21.189  3.100   -85.356  1.00 32.16  ? 364  ASP C CG  1 
ATOM   9907  O OD1 . ASP C 1 371 ? 20.874  3.261   -84.150  1.00 34.81  ? 364  ASP C OD1 1 
ATOM   9908  O OD2 . ASP C 1 371 ? 21.554  1.994   -85.841  1.00 35.68  ? 364  ASP C OD2 1 
ATOM   9909  N N   A MET C 1 372 ? 20.001  6.989   -87.553  0.61 24.75  ? 365  MET C N   1 
ATOM   9910  N N   B MET C 1 372 ? 20.000  6.989   -87.559  0.39 24.08  ? 365  MET C N   1 
ATOM   9911  C CA  A MET C 1 372 ? 20.133  8.141   -88.478  0.61 25.67  ? 365  MET C CA  1 
ATOM   9912  C CA  B MET C 1 372 ? 20.127  8.146   -88.483  0.39 24.31  ? 365  MET C CA  1 
ATOM   9913  C C   A MET C 1 372 ? 19.792  9.428   -87.723  0.61 24.84  ? 365  MET C C   1 
ATOM   9914  C C   B MET C 1 372 ? 19.791  9.431   -87.724  0.39 24.13  ? 365  MET C C   1 
ATOM   9915  O O   A MET C 1 372 ? 20.632  10.355  -87.726  0.61 26.50  ? 365  MET C O   1 
ATOM   9916  O O   B MET C 1 372 ? 20.628  10.359  -87.731  0.39 25.18  ? 365  MET C O   1 
ATOM   9917  C CB  A MET C 1 372 ? 19.205  7.956   -89.681  0.61 27.78  ? 365  MET C CB  1 
ATOM   9918  C CB  B MET C 1 372 ? 19.191  8.004   -89.687  0.39 24.88  ? 365  MET C CB  1 
ATOM   9919  C CG  A MET C 1 372 ? 19.233  9.080   -90.693  0.61 29.86  ? 365  MET C CG  1 
ATOM   9920  C CG  B MET C 1 372 ? 19.318  9.133   -90.706  0.39 25.51  ? 365  MET C CG  1 
ATOM   9921  S SD  A MET C 1 372 ? 18.442  8.577   -92.266  0.61 35.73  ? 365  MET C SD  1 
ATOM   9922  S SD  B MET C 1 372 ? 18.295  10.601  -90.362  0.39 27.16  ? 365  MET C SD  1 
ATOM   9923  C CE  A MET C 1 372 ? 16.919  7.859   -91.652  0.61 34.21  ? 365  MET C CE  1 
ATOM   9924  C CE  B MET C 1 372 ? 18.241  11.391  -91.971  0.39 27.66  ? 365  MET C CE  1 
ATOM   9925  N N   . LEU C 1 373 ? 18.628  9.461   -87.071  1.00 23.76  ? 366  LEU C N   1 
ATOM   9926  C CA  . LEU C 1 373 ? 18.122  10.646  -86.329  1.00 24.74  ? 366  LEU C CA  1 
ATOM   9927  C C   . LEU C 1 373 ? 19.039  10.990  -85.153  1.00 25.51  ? 366  LEU C C   1 
ATOM   9928  O O   . LEU C 1 373 ? 19.317  12.194  -84.964  1.00 24.72  ? 366  LEU C O   1 
ATOM   9929  C CB  . LEU C 1 373 ? 16.705  10.351  -85.829  1.00 23.96  ? 366  LEU C CB  1 
ATOM   9930  C CG  . LEU C 1 373 ? 15.605  10.513  -86.873  1.00 23.78  ? 366  LEU C CG  1 
ATOM   9931  C CD1 . LEU C 1 373 ? 14.255  10.087  -86.329  1.00 24.21  ? 366  LEU C CD1 1 
ATOM   9932  C CD2 . LEU C 1 373 ? 15.536  11.950  -87.374  1.00 23.89  ? 366  LEU C CD2 1 
ATOM   9933  N N   . LEU C 1 374 ? 19.453  9.985   -84.376  1.00 27.93  ? 367  LEU C N   1 
ATOM   9934  C CA  . LEU C 1 374 ? 20.308  10.188  -83.176  1.00 29.72  ? 367  LEU C CA  1 
ATOM   9935  C C   . LEU C 1 374 ? 21.641  10.791  -83.620  1.00 33.37  ? 367  LEU C C   1 
ATOM   9936  O O   . LEU C 1 374 ? 22.100  11.751  -82.955  1.00 34.98  ? 367  LEU C O   1 
ATOM   9937  C CB  . LEU C 1 374 ? 20.511  8.861   -82.443  1.00 28.15  ? 367  LEU C CB  1 
ATOM   9938  C CG  . LEU C 1 374 ? 21.246  8.973   -81.104  1.00 27.45  ? 367  LEU C CG  1 
ATOM   9939  C CD1 . LEU C 1 374 ? 20.608  10.020  -80.183  1.00 26.49  ? 367  LEU C CD1 1 
ATOM   9940  C CD2 . LEU C 1 374 ? 21.325  7.619   -80.393  1.00 26.62  ? 367  LEU C CD2 1 
ATOM   9941  N N   . ASP C 1 375 ? 22.224  10.269  -84.711  1.00 37.68  ? 368  ASP C N   1 
ATOM   9942  C CA  . ASP C 1 375 ? 23.492  10.802  -85.289  1.00 37.27  ? 368  ASP C CA  1 
ATOM   9943  C C   . ASP C 1 375 ? 23.275  12.278  -85.603  1.00 34.17  ? 368  ASP C C   1 
ATOM   9944  O O   . ASP C 1 375 ? 24.087  13.103  -85.179  1.00 32.07  ? 368  ASP C O   1 
ATOM   9945  C CB  . ASP C 1 375 ? 23.949  10.030  -86.518  1.00 40.19  ? 368  ASP C CB  1 
ATOM   9946  C CG  . ASP C 1 375 ? 24.596  8.712   -86.141  1.00 45.37  ? 368  ASP C CG  1 
ATOM   9947  O OD1 . ASP C 1 375 ? 24.605  8.357   -84.938  1.00 47.96  ? 368  ASP C OD1 1 
ATOM   9948  O OD2 . ASP C 1 375 ? 25.084  8.054   -87.049  1.00 55.49  ? 368  ASP C OD2 1 
ATOM   9949  N N   . GLY C 1 376 ? 22.181  12.589  -86.287  1.00 33.35  ? 369  GLY C N   1 
ATOM   9950  C CA  . GLY C 1 376 ? 21.815  13.979  -86.604  1.00 32.35  ? 369  GLY C CA  1 
ATOM   9951  C C   . GLY C 1 376 ? 21.798  14.844  -85.352  1.00 30.61  ? 369  GLY C C   1 
ATOM   9952  O O   . GLY C 1 376 ? 22.380  15.946  -85.369  1.00 29.23  ? 369  GLY C O   1 
ATOM   9953  N N   . PHE C 1 377 ? 21.136  14.376  -84.296  1.00 28.97  ? 370  PHE C N   1 
ATOM   9954  C CA  . PHE C 1 377 ? 20.931  15.159  -83.052  1.00 29.36  ? 370  PHE C CA  1 
ATOM   9955  C C   . PHE C 1 377 ? 22.259  15.318  -82.312  1.00 29.32  ? 370  PHE C C   1 
ATOM   9956  O O   . PHE C 1 377 ? 22.554  16.444  -81.880  1.00 28.88  ? 370  PHE C O   1 
ATOM   9957  C CB  . PHE C 1 377 ? 19.887  14.499  -82.156  1.00 26.96  ? 370  PHE C CB  1 
ATOM   9958  C CG  . PHE C 1 377 ? 18.495  14.511  -82.719  1.00 26.33  ? 370  PHE C CG  1 
ATOM   9959  C CD1 . PHE C 1 377 ? 17.997  15.645  -83.341  1.00 27.78  ? 370  PHE C CD1 1 
ATOM   9960  C CD2 . PHE C 1 377 ? 17.685  13.395  -82.621  1.00 25.22  ? 370  PHE C CD2 1 
ATOM   9961  C CE1 . PHE C 1 377 ? 16.722  15.658  -83.883  1.00 26.75  ? 370  PHE C CE1 1 
ATOM   9962  C CE2 . PHE C 1 377 ? 16.399  13.417  -83.137  1.00 26.62  ? 370  PHE C CE2 1 
ATOM   9963  C CZ  . PHE C 1 377 ? 15.928  14.544  -83.781  1.00 27.23  ? 370  PHE C CZ  1 
ATOM   9964  N N   . ARG C 1 378 ? 23.013  14.229  -82.169  1.00 30.57  ? 371  ARG C N   1 
ATOM   9965  C CA  . ARG C 1 378 ? 24.359  14.241  -81.537  1.00 36.61  ? 371  ARG C CA  1 
ATOM   9966  C C   . ARG C 1 378 ? 25.236  15.298  -82.221  1.00 34.61  ? 371  ARG C C   1 
ATOM   9967  O O   . ARG C 1 378 ? 25.958  16.001  -81.510  1.00 38.78  ? 371  ARG C O   1 
ATOM   9968  C CB  . ARG C 1 378 ? 24.970  12.836  -81.552  1.00 43.06  ? 371  ARG C CB  1 
ATOM   9969  C CG  . ARG C 1 378 ? 24.396  11.933  -80.455  1.00 49.96  ? 371  ARG C CG  1 
ATOM   9970  C CD  . ARG C 1 378 ? 25.321  10.889  -79.866  1.00 57.35  ? 371  ARG C CD  1 
ATOM   9971  N NE  . ARG C 1 378 ? 25.329  9.627   -80.608  1.00 66.60  ? 371  ARG C NE  1 
ATOM   9972  C CZ  . ARG C 1 378 ? 24.909  8.443   -80.144  1.00 70.20  ? 371  ARG C CZ  1 
ATOM   9973  N NH1 . ARG C 1 378 ? 24.431  8.326   -78.917  1.00 62.61  ? 371  ARG C NH1 1 
ATOM   9974  N NH2 . ARG C 1 378 ? 24.964  7.373   -80.921  1.00 79.03  ? 371  ARG C NH2 1 
ATOM   9975  N N   . GLN C 1 379 ? 25.141  15.420  -83.542  1.00 36.76  ? 372  GLN C N   1 
ATOM   9976  C CA  . GLN C 1 379 ? 25.902  16.420  -84.343  1.00 37.44  ? 372  GLN C CA  1 
ATOM   9977  C C   . GLN C 1 379 ? 25.453  17.835  -83.960  1.00 35.40  ? 372  GLN C C   1 
ATOM   9978  O O   . GLN C 1 379 ? 26.325  18.676  -83.702  1.00 36.36  ? 372  GLN C O   1 
ATOM   9979  C CB  . GLN C 1 379 ? 25.738  16.167  -85.849  1.00 39.01  ? 372  GLN C CB  1 
ATOM   9980  C CG  . GLN C 1 379 ? 26.533  17.112  -86.741  1.00 41.25  ? 372  GLN C CG  1 
ATOM   9981  C CD  . GLN C 1 379 ? 28.003  17.175  -86.371  1.00 46.95  ? 372  GLN C CD  1 
ATOM   9982  O OE1 . GLN C 1 379 ? 28.606  16.205  -85.907  1.00 45.24  ? 372  GLN C OE1 1 
ATOM   9983  N NE2 . GLN C 1 379 ? 28.608  18.338  -86.559  1.00 48.41  ? 372  GLN C NE2 1 
ATOM   9984  N N   . LEU C 1 380 ? 24.142  18.076  -83.904  1.00 34.75  ? 373  LEU C N   1 
ATOM   9985  C CA  . LEU C 1 380 ? 23.576  19.388  -83.496  1.00 35.26  ? 373  LEU C CA  1 
ATOM   9986  C C   . LEU C 1 380 ? 23.977  19.690  -82.043  1.00 36.13  ? 373  LEU C C   1 
ATOM   9987  O O   . LEU C 1 380 ? 24.139  20.882  -81.713  1.00 33.29  ? 373  LEU C O   1 
ATOM   9988  C CB  . LEU C 1 380 ? 22.054  19.361  -83.667  1.00 34.99  ? 373  LEU C CB  1 
ATOM   9989  C CG  . LEU C 1 380 ? 21.563  19.364  -85.118  1.00 34.24  ? 373  LEU C CG  1 
ATOM   9990  C CD1 . LEU C 1 380 ? 20.043  19.293  -85.179  1.00 35.28  ? 373  LEU C CD1 1 
ATOM   9991  C CD2 . LEU C 1 380 ? 22.048  20.592  -85.875  1.00 32.97  ? 373  LEU C CD2 1 
ATOM   9992  N N   . ALA C 1 381 ? 24.146  18.654  -81.212  1.00 35.63  ? 374  ALA C N   1 
ATOM   9993  C CA  . ALA C 1 381 ? 24.564  18.795  -79.801  1.00 38.96  ? 374  ALA C CA  1 
ATOM   9994  C C   . ALA C 1 381 ? 26.004  19.309  -79.778  1.00 40.43  ? 374  ALA C C   1 
ATOM   9995  O O   . ALA C 1 381 ? 26.268  20.260  -79.015  1.00 41.66  ? 374  ALA C O   1 
ATOM   9996  C CB  . ALA C 1 381 ? 24.439  17.482  -79.071  1.00 40.25  ? 374  ALA C CB  1 
ATOM   9997  N N   . ARG C 1 382 ? 26.881  18.703  -80.588  1.00 43.23  ? 375  ARG C N   1 
ATOM   9998  C CA  . ARG C 1 382 ? 28.289  19.141  -80.759  1.00 43.33  ? 375  ARG C CA  1 
ATOM   9999  C C   . ARG C 1 382 ? 28.306  20.607  -81.185  1.00 41.96  ? 375  ARG C C   1 
ATOM   10000 O O   . ARG C 1 382 ? 29.141  21.352  -80.666  1.00 42.37  ? 375  ARG C O   1 
ATOM   10001 C CB  . ARG C 1 382 ? 29.039  18.266  -81.763  1.00 46.47  ? 375  ARG C CB  1 
ATOM   10002 C CG  . ARG C 1 382 ? 29.733  17.091  -81.096  1.00 52.98  ? 375  ARG C CG  1 
ATOM   10003 C CD  . ARG C 1 382 ? 30.568  16.222  -82.015  1.00 59.59  ? 375  ARG C CD  1 
ATOM   10004 N NE  . ARG C 1 382 ? 30.141  14.840  -81.836  1.00 68.91  ? 375  ARG C NE  1 
ATOM   10005 C CZ  . ARG C 1 382 ? 29.313  14.173  -82.649  1.00 71.10  ? 375  ARG C CZ  1 
ATOM   10006 N NH1 . ARG C 1 382 ? 28.852  14.730  -83.753  1.00 66.49  ? 375  ARG C NH1 1 
ATOM   10007 N NH2 . ARG C 1 382 ? 28.960  12.925  -82.372  1.00 73.24  ? 375  ARG C NH2 1 
ATOM   10008 N N   . GLU C 1 383 ? 27.389  21.009  -82.054  1.00 40.51  ? 376  GLU C N   1 
ATOM   10009 C CA  . GLU C 1 383 ? 27.393  22.359  -82.666  1.00 42.13  ? 376  GLU C CA  1 
ATOM   10010 C C   . GLU C 1 383 ? 26.781  23.384  -81.702  1.00 38.95  ? 376  GLU C C   1 
ATOM   10011 O O   . GLU C 1 383 ? 27.174  24.565  -81.778  1.00 39.33  ? 376  GLU C O   1 
ATOM   10012 C CB  . GLU C 1 383 ? 26.652  22.303  -84.000  1.00 45.82  ? 376  GLU C CB  1 
ATOM   10013 C CG  . GLU C 1 383 ? 27.298  21.339  -84.974  1.00 48.05  ? 376  GLU C CG  1 
ATOM   10014 C CD  . GLU C 1 383 ? 26.818  21.470  -86.412  1.00 48.73  ? 376  GLU C CD  1 
ATOM   10015 O OE1 . GLU C 1 383 ? 26.456  22.594  -86.807  1.00 48.55  ? 376  GLU C OE1 1 
ATOM   10016 O OE2 . GLU C 1 383 ? 26.813  20.451  -87.137  1.00 48.40  ? 376  GLU C OE2 1 
ATOM   10017 N N   . TYR C 1 384 ? 25.867  22.963  -80.828  1.00 39.67  ? 377  TYR C N   1 
ATOM   10018 C CA  . TYR C 1 384 ? 25.092  23.878  -79.948  1.00 39.46  ? 377  TYR C CA  1 
ATOM   10019 C C   . TYR C 1 384 ? 25.178  23.397  -78.507  1.00 36.70  ? 377  TYR C C   1 
ATOM   10020 O O   . TYR C 1 384 ? 24.169  23.060  -77.901  1.00 40.14  ? 377  TYR C O   1 
ATOM   10021 C CB  . TYR C 1 384 ? 23.646  23.986  -80.441  1.00 38.71  ? 377  TYR C CB  1 
ATOM   10022 C CG  . TYR C 1 384 ? 23.479  24.655  -81.783  1.00 36.38  ? 377  TYR C CG  1 
ATOM   10023 C CD1 . TYR C 1 384 ? 23.516  23.937  -82.964  1.00 35.35  ? 377  TYR C CD1 1 
ATOM   10024 C CD2 . TYR C 1 384 ? 23.206  26.013  -81.858  1.00 36.63  ? 377  TYR C CD2 1 
ATOM   10025 C CE1 . TYR C 1 384 ? 23.363  24.563  -84.190  1.00 37.05  ? 377  TYR C CE1 1 
ATOM   10026 C CE2 . TYR C 1 384 ? 23.024  26.651  -83.073  1.00 38.63  ? 377  TYR C CE2 1 
ATOM   10027 C CZ  . TYR C 1 384 ? 23.106  25.923  -84.244  1.00 38.75  ? 377  TYR C CZ  1 
ATOM   10028 O OH  . TYR C 1 384 ? 22.943  26.548  -85.442  1.00 47.52  ? 377  TYR C OH  1 
ATOM   10029 N N   . PRO C 1 385 ? 26.391  23.369  -77.922  1.00 36.44  ? 378  PRO C N   1 
ATOM   10030 C CA  . PRO C 1 385 ? 26.569  23.017  -76.514  1.00 36.86  ? 378  PRO C CA  1 
ATOM   10031 C C   . PRO C 1 385 ? 26.093  24.116  -75.550  1.00 35.85  ? 378  PRO C C   1 
ATOM   10032 O O   . PRO C 1 385 ? 25.914  23.832  -74.383  1.00 32.09  ? 378  PRO C O   1 
ATOM   10033 C CB  . PRO C 1 385 ? 28.087  22.846  -76.391  1.00 37.99  ? 378  PRO C CB  1 
ATOM   10034 C CG  . PRO C 1 385 ? 28.629  23.802  -77.427  1.00 36.64  ? 378  PRO C CG  1 
ATOM   10035 C CD  . PRO C 1 385 ? 27.664  23.691  -78.586  1.00 36.47  ? 378  PRO C CD  1 
ATOM   10036 N N   . ASP C 1 386 ? 25.924  25.335  -76.069  1.00 35.54  ? 379  ASP C N   1 
ATOM   10037 C CA  . ASP C 1 386 ? 25.357  26.503  -75.349  1.00 36.01  ? 379  ASP C CA  1 
ATOM   10038 C C   . ASP C 1 386 ? 23.865  26.270  -75.074  1.00 37.18  ? 379  ASP C C   1 
ATOM   10039 O O   . ASP C 1 386 ? 23.325  26.925  -74.148  1.00 43.83  ? 379  ASP C O   1 
ATOM   10040 C CB  . ASP C 1 386 ? 25.583  27.782  -76.159  1.00 37.19  ? 379  ASP C CB  1 
ATOM   10041 C CG  . ASP C 1 386 ? 25.132  27.685  -77.608  1.00 40.76  ? 379  ASP C CG  1 
ATOM   10042 O OD1 . ASP C 1 386 ? 25.387  26.614  -78.247  1.00 37.79  ? 379  ASP C OD1 1 
ATOM   10043 O OD2 . ASP C 1 386 ? 24.517  28.673  -78.089  1.00 45.48  ? 379  ASP C OD2 1 
ATOM   10044 N N   . LEU C 1 387 ? 23.214  25.403  -75.858  1.00 33.95  ? 380  LEU C N   1 
ATOM   10045 C CA  . LEU C 1 387 ? 21.748  25.151  -75.797  1.00 33.70  ? 380  LEU C CA  1 
ATOM   10046 C C   . LEU C 1 387 ? 21.468  23.706  -75.401  1.00 31.01  ? 380  LEU C C   1 
ATOM   10047 O O   . LEU C 1 387 ? 20.549  23.484  -74.616  1.00 29.46  ? 380  LEU C O   1 
ATOM   10048 C CB  . LEU C 1 387 ? 21.165  25.451  -77.174  1.00 36.33  ? 380  LEU C CB  1 
ATOM   10049 C CG  . LEU C 1 387 ? 21.316  26.899  -77.619  1.00 38.94  ? 380  LEU C CG  1 
ATOM   10050 C CD1 . LEU C 1 387 ? 20.644  27.110  -78.958  1.00 40.60  ? 380  LEU C CD1 1 
ATOM   10051 C CD2 . LEU C 1 387 ? 20.716  27.840  -76.589  1.00 40.31  ? 380  LEU C CD2 1 
ATOM   10052 N N   . VAL C 1 388 ? 22.249  22.767  -75.924  1.00 31.16  ? 381  VAL C N   1 
ATOM   10053 C CA  . VAL C 1 388 ? 21.970  21.313  -75.781  1.00 30.31  ? 381  VAL C CA  1 
ATOM   10054 C C   . VAL C 1 388 ? 23.016  20.690  -74.873  1.00 29.70  ? 381  VAL C C   1 
ATOM   10055 O O   . VAL C 1 388 ? 24.198  20.856  -75.148  1.00 30.53  ? 381  VAL C O   1 
ATOM   10056 C CB  . VAL C 1 388 ? 21.975  20.624  -77.156  1.00 29.63  ? 381  VAL C CB  1 
ATOM   10057 C CG1 . VAL C 1 388 ? 21.800  19.114  -77.024  1.00 28.79  ? 381  VAL C CG1 1 
ATOM   10058 C CG2 . VAL C 1 388 ? 20.927  21.252  -78.059  1.00 28.16  ? 381  VAL C CG2 1 
ATOM   10059 N N   A GLN C 1 389 ? 22.571  19.981  -73.840  0.50 30.89  ? 382  GLN C N   1 
ATOM   10060 N N   B GLN C 1 389 ? 22.582  19.983  -73.830  0.50 30.48  ? 382  GLN C N   1 
ATOM   10061 C CA  A GLN C 1 389 ? 23.457  19.217  -72.932  0.50 32.22  ? 382  GLN C CA  1 
ATOM   10062 C CA  B GLN C 1 389 ? 23.500  19.216  -72.953  0.50 31.53  ? 382  GLN C CA  1 
ATOM   10063 C C   A GLN C 1 389 ? 23.843  17.936  -73.671  0.50 32.87  ? 382  GLN C C   1 
ATOM   10064 C C   B GLN C 1 389 ? 23.859  17.928  -73.690  0.50 32.46  ? 382  GLN C C   1 
ATOM   10065 O O   A GLN C 1 389 ? 25.047  17.731  -73.888  0.50 36.62  ? 382  GLN C O   1 
ATOM   10066 O O   B GLN C 1 389 ? 25.061  17.708  -73.917  0.50 36.12  ? 382  GLN C O   1 
ATOM   10067 C CB  A GLN C 1 389 ? 22.781  18.978  -71.581  0.50 33.37  ? 382  GLN C CB  1 
ATOM   10068 C CB  B GLN C 1 389 ? 22.913  18.948  -71.569  0.50 32.00  ? 382  GLN C CB  1 
ATOM   10069 C CG  A GLN C 1 389 ? 23.755  18.565  -70.483  0.50 34.58  ? 382  GLN C CG  1 
ATOM   10070 C CG  B GLN C 1 389 ? 23.662  17.859  -70.797  0.50 32.77  ? 382  GLN C CG  1 
ATOM   10071 C CD  A GLN C 1 389 ? 23.096  18.391  -69.131  0.50 34.58  ? 382  GLN C CD  1 
ATOM   10072 C CD  B GLN C 1 389 ? 24.997  18.276  -70.212  0.50 32.71  ? 382  GLN C CD  1 
ATOM   10073 O OE1 A GLN C 1 389 ? 22.261  19.187  -68.703  0.50 33.42  ? 382  GLN C OE1 1 
ATOM   10074 O OE1 B GLN C 1 389 ? 25.249  19.446  -69.936  0.50 33.38  ? 382  GLN C OE1 1 
ATOM   10075 N NE2 A GLN C 1 389 ? 23.470  17.329  -68.437  0.50 34.92  ? 382  GLN C NE2 1 
ATOM   10076 N NE2 B GLN C 1 389 ? 25.867  17.303  -69.988  0.50 30.96  ? 382  GLN C NE2 1 
ATOM   10077 N N   . GLU C 1 390 ? 22.867  17.137  -74.098  1.00 32.11  ? 383  GLU C N   1 
ATOM   10078 C CA  . GLU C 1 390 ? 23.144  15.839  -74.759  1.00 33.73  ? 383  GLU C CA  1 
ATOM   10079 C C   . GLU C 1 390 ? 21.900  15.358  -75.524  1.00 33.31  ? 383  GLU C C   1 
ATOM   10080 O O   . GLU C 1 390 ? 20.793  15.836  -75.236  1.00 36.19  ? 383  GLU C O   1 
ATOM   10081 C CB  . GLU C 1 390 ? 23.673  14.906  -73.667  1.00 35.30  ? 383  GLU C CB  1 
ATOM   10082 C CG  . GLU C 1 390 ? 23.053  13.541  -73.636  1.00 37.59  ? 383  GLU C CG  1 
ATOM   10083 C CD  . GLU C 1 390 ? 23.535  12.635  -72.515  1.00 40.16  ? 383  GLU C CD  1 
ATOM   10084 O OE1 . GLU C 1 390 ? 23.412  13.049  -71.330  1.00 44.30  ? 383  GLU C OE1 1 
ATOM   10085 O OE2 . GLU C 1 390 ? 23.970  11.495  -72.826  1.00 37.52  ? 383  GLU C OE2 1 
ATOM   10086 N N   . ALA C 1 391 ? 22.096  14.483  -76.508  1.00 29.73  ? 384  ALA C N   1 
ATOM   10087 C CA  . ALA C 1 391 ? 21.026  13.708  -77.172  1.00 29.85  ? 384  ALA C CA  1 
ATOM   10088 C C   . ALA C 1 391 ? 21.271  12.217  -76.917  1.00 27.98  ? 384  ALA C C   1 
ATOM   10089 O O   . ALA C 1 391 ? 22.432  11.784  -77.044  1.00 27.13  ? 384  ALA C O   1 
ATOM   10090 C CB  . ALA C 1 391 ? 20.986  14.028  -78.651  1.00 31.91  ? 384  ALA C CB  1 
ATOM   10091 N N   . ARG C 1 392 ? 20.214  11.485  -76.548  1.00 26.30  ? 385  ARG C N   1 
ATOM   10092 C CA  . ARG C 1 392 ? 20.252  10.030  -76.261  1.00 25.72  ? 385  ARG C CA  1 
ATOM   10093 C C   . ARG C 1 392 ? 19.157  9.340   -77.050  1.00 23.84  ? 385  ARG C C   1 
ATOM   10094 O O   . ARG C 1 392 ? 18.206  10.039  -77.450  1.00 21.78  ? 385  ARG C O   1 
ATOM   10095 C CB  . ARG C 1 392 ? 19.911  9.686   -74.810  1.00 28.52  ? 385  ARG C CB  1 
ATOM   10096 C CG  . ARG C 1 392 ? 20.319  10.707  -73.758  1.00 30.54  ? 385  ARG C CG  1 
ATOM   10097 C CD  . ARG C 1 392 ? 19.971  10.226  -72.347  1.00 29.78  ? 385  ARG C CD  1 
ATOM   10098 N NE  . ARG C 1 392 ? 18.880  10.979  -71.760  1.00 28.40  ? 385  ARG C NE  1 
ATOM   10099 C CZ  . ARG C 1 392 ? 18.974  12.230  -71.315  1.00 31.81  ? 385  ARG C CZ  1 
ATOM   10100 N NH1 . ARG C 1 392 ? 20.122  12.893  -71.385  1.00 30.91  ? 385  ARG C NH1 1 
ATOM   10101 N NH2 . ARG C 1 392 ? 17.908  12.819  -70.790  1.00 36.01  ? 385  ARG C NH2 1 
ATOM   10102 N N   . GLY C 1 393 ? 19.244  8.017   -77.156  1.00 23.64  ? 386  GLY C N   1 
ATOM   10103 C CA  . GLY C 1 393 ? 18.147  7.200   -77.696  1.00 23.09  ? 386  GLY C CA  1 
ATOM   10104 C C   . GLY C 1 393 ? 18.533  5.751   -77.914  1.00 23.13  ? 386  GLY C C   1 
ATOM   10105 O O   . GLY C 1 393 ? 19.706  5.359   -77.708  1.00 20.24  ? 386  GLY C O   1 
ATOM   10106 N N   . LYS C 1 394 ? 17.533  4.983   -78.310  1.00 23.37  ? 387  LYS C N   1 
ATOM   10107 C CA  . LYS C 1 394 ? 17.642  3.578   -78.752  1.00 24.35  ? 387  LYS C CA  1 
ATOM   10108 C C   . LYS C 1 394 ? 16.461  3.365   -79.700  1.00 24.88  ? 387  LYS C C   1 
ATOM   10109 O O   . LYS C 1 394 ? 15.285  3.598   -79.289  1.00 25.13  ? 387  LYS C O   1 
ATOM   10110 C CB  . LYS C 1 394 ? 17.599  2.681   -77.520  1.00 25.98  ? 387  LYS C CB  1 
ATOM   10111 C CG  . LYS C 1 394 ? 17.480  1.199   -77.803  1.00 27.63  ? 387  LYS C CG  1 
ATOM   10112 C CD  . LYS C 1 394 ? 18.789  0.543   -77.944  1.00 30.39  ? 387  LYS C CD  1 
ATOM   10113 C CE  . LYS C 1 394 ? 18.916  -0.678  -77.051  1.00 34.42  ? 387  LYS C CE  1 
ATOM   10114 N NZ  . LYS C 1 394 ? 20.313  -1.175  -76.958  1.00 37.63  ? 387  LYS C NZ  1 
ATOM   10115 N N   . GLY C 1 395 ? 16.731  3.001   -80.943  1.00 24.99  ? 388  GLY C N   1 
ATOM   10116 C CA  . GLY C 1 395 ? 15.676  2.989   -81.970  1.00 23.73  ? 388  GLY C CA  1 
ATOM   10117 C C   . GLY C 1 395 ? 15.016  4.346   -82.047  1.00 23.04  ? 388  GLY C C   1 
ATOM   10118 O O   . GLY C 1 395 ? 15.748  5.355   -82.023  1.00 19.77  ? 388  GLY C O   1 
ATOM   10119 N N   . MET C 1 396 ? 13.681  4.371   -82.085  1.00 23.34  ? 389  MET C N   1 
ATOM   10120 C CA  . MET C 1 396 ? 12.895  5.612   -82.298  1.00 23.84  ? 389  MET C CA  1 
ATOM   10121 C C   . MET C 1 396 ? 12.444  6.187   -80.966  1.00 22.09  ? 389  MET C C   1 
ATOM   10122 O O   . MET C 1 396 ? 11.538  7.003   -80.961  1.00 23.58  ? 389  MET C O   1 
ATOM   10123 C CB  . MET C 1 396 ? 11.689  5.315   -83.184  1.00 25.36  ? 389  MET C CB  1 
ATOM   10124 C CG  . MET C 1 396 ? 12.117  4.992   -84.611  1.00 27.01  ? 389  MET C CG  1 
ATOM   10125 S SD  . MET C 1 396 ? 12.775  6.434   -85.489  1.00 27.41  ? 389  MET C SD  1 
ATOM   10126 C CE  . MET C 1 396 ? 11.322  6.872   -86.451  1.00 24.89  ? 389  MET C CE  1 
ATOM   10127 N N   . LEU C 1 397 ? 13.072  5.763   -79.885  1.00 23.98  ? 390  LEU C N   1 
ATOM   10128 C CA  . LEU C 1 397 ? 12.882  6.364   -78.544  1.00 25.93  ? 390  LEU C CA  1 
ATOM   10129 C C   . LEU C 1 397 ? 14.102  7.245   -78.268  1.00 24.35  ? 390  LEU C C   1 
ATOM   10130 O O   . LEU C 1 397 ? 15.185  6.699   -77.987  1.00 21.98  ? 390  LEU C O   1 
ATOM   10131 C CB  . LEU C 1 397 ? 12.715  5.259   -77.499  1.00 28.45  ? 390  LEU C CB  1 
ATOM   10132 C CG  . LEU C 1 397 ? 12.393  5.763   -76.089  1.00 32.23  ? 390  LEU C CG  1 
ATOM   10133 C CD1 . LEU C 1 397 ? 11.109  6.600   -76.064  1.00 31.61  ? 390  LEU C CD1 1 
ATOM   10134 C CD2 . LEU C 1 397 ? 12.321  4.604   -75.098  1.00 33.11  ? 390  LEU C CD2 1 
ATOM   10135 N N   . MET C 1 398 ? 13.920  8.555   -78.391  1.00 23.29  ? 391  MET C N   1 
ATOM   10136 C CA  . MET C 1 398 ? 15.026  9.534   -78.337  1.00 22.49  ? 391  MET C CA  1 
ATOM   10137 C C   . MET C 1 398 ? 14.608  10.742  -77.507  1.00 20.79  ? 391  MET C C   1 
ATOM   10138 O O   . MET C 1 398 ? 13.401  11.004  -77.379  1.00 20.16  ? 391  MET C O   1 
ATOM   10139 C CB  . MET C 1 398 ? 15.393  9.995   -79.751  1.00 23.29  ? 391  MET C CB  1 
ATOM   10140 C CG  . MET C 1 398 ? 16.164  8.953   -80.535  1.00 23.57  ? 391  MET C CG  1 
ATOM   10141 S SD  . MET C 1 398 ? 16.228  9.309   -82.305  1.00 23.66  ? 391  MET C SD  1 
ATOM   10142 C CE  . MET C 1 398 ? 14.478  9.240   -82.700  1.00 25.06  ? 391  MET C CE  1 
ATOM   10143 N N   . ALA C 1 399 ? 15.607  11.434  -76.975  1.00 20.85  ? 392  ALA C N   1 
ATOM   10144 C CA  . ALA C 1 399 ? 15.474  12.692  -76.225  1.00 22.61  ? 392  ALA C CA  1 
ATOM   10145 C C   . ALA C 1 399 ? 16.658  13.613  -76.529  1.00 24.29  ? 392  ALA C C   1 
ATOM   10146 O O   . ALA C 1 399 ? 17.785  13.117  -76.766  1.00 21.69  ? 392  ALA C O   1 
ATOM   10147 C CB  . ALA C 1 399 ? 15.410  12.382  -74.763  1.00 24.01  ? 392  ALA C CB  1 
ATOM   10148 N N   . ILE C 1 400 ? 16.378  14.911  -76.515  1.00 27.12  ? 393  ILE C N   1 
ATOM   10149 C CA  . ILE C 1 400 ? 17.378  16.009  -76.444  1.00 27.69  ? 393  ILE C CA  1 
ATOM   10150 C C   . ILE C 1 400 ? 17.219  16.674  -75.082  1.00 28.40  ? 393  ILE C C   1 
ATOM   10151 O O   . ILE C 1 400 ? 16.152  17.249  -74.839  1.00 24.88  ? 393  ILE C O   1 
ATOM   10152 C CB  . ILE C 1 400 ? 17.171  17.010  -77.588  1.00 27.39  ? 393  ILE C CB  1 
ATOM   10153 C CG1 . ILE C 1 400 ? 17.254  16.312  -78.942  1.00 28.60  ? 393  ILE C CG1 1 
ATOM   10154 C CG2 . ILE C 1 400 ? 18.159  18.154  -77.495  1.00 27.89  ? 393  ILE C CG2 1 
ATOM   10155 C CD1 . ILE C 1 400 ? 16.593  17.089  -80.060  1.00 30.97  ? 393  ILE C CD1 1 
ATOM   10156 N N   . GLU C 1 401 ? 18.256  16.593  -74.244  1.00 33.21  ? 394  GLU C N   1 
ATOM   10157 C CA  . GLU C 1 401 ? 18.357  17.342  -72.970  1.00 34.91  ? 394  GLU C CA  1 
ATOM   10158 C C   . GLU C 1 401 ? 18.972  18.710  -73.267  1.00 34.88  ? 394  GLU C C   1 
ATOM   10159 O O   . GLU C 1 401 ? 20.095  18.747  -73.790  1.00 30.96  ? 394  GLU C O   1 
ATOM   10160 C CB  . GLU C 1 401 ? 19.193  16.557  -71.963  1.00 38.31  ? 394  GLU C CB  1 
ATOM   10161 C CG  . GLU C 1 401 ? 19.189  17.179  -70.582  1.00 40.92  ? 394  GLU C CG  1 
ATOM   10162 C CD  . GLU C 1 401 ? 20.030  16.427  -69.566  1.00 48.04  ? 394  GLU C CD  1 
ATOM   10163 O OE1 . GLU C 1 401 ? 20.956  15.677  -70.001  1.00 50.88  ? 394  GLU C OE1 1 
ATOM   10164 O OE2 . GLU C 1 401 ? 19.727  16.549  -68.342  1.00 52.28  ? 394  GLU C OE2 1 
ATOM   10165 N N   . PHE C 1 402 ? 18.260  19.789  -72.952  1.00 37.05  ? 395  PHE C N   1 
ATOM   10166 C CA  . PHE C 1 402 ? 18.769  21.175  -73.092  1.00 41.01  ? 395  PHE C CA  1 
ATOM   10167 C C   . PHE C 1 402 ? 19.435  21.590  -71.780  1.00 45.97  ? 395  PHE C C   1 
ATOM   10168 O O   . PHE C 1 402 ? 19.348  20.863  -70.775  1.00 47.23  ? 395  PHE C O   1 
ATOM   10169 C CB  . PHE C 1 402 ? 17.642  22.103  -73.538  1.00 41.03  ? 395  PHE C CB  1 
ATOM   10170 C CG  . PHE C 1 402 ? 17.126  21.700  -74.891  1.00 42.27  ? 395  PHE C CG  1 
ATOM   10171 C CD1 . PHE C 1 402 ? 16.238  20.649  -75.017  1.00 42.23  ? 395  PHE C CD1 1 
ATOM   10172 C CD2 . PHE C 1 402 ? 17.612  22.297  -76.041  1.00 43.85  ? 395  PHE C CD2 1 
ATOM   10173 C CE1 . PHE C 1 402 ? 15.811  20.235  -76.266  1.00 42.34  ? 395  PHE C CE1 1 
ATOM   10174 C CE2 . PHE C 1 402 ? 17.168  21.893  -77.288  1.00 43.32  ? 395  PHE C CE2 1 
ATOM   10175 C CZ  . PHE C 1 402 ? 16.267  20.864  -77.397  1.00 41.86  ? 395  PHE C CZ  1 
ATOM   10176 N N   . VAL C 1 403 ? 20.126  22.722  -71.821  1.00 48.54  ? 396  VAL C N   1 
ATOM   10177 C CA  . VAL C 1 403 ? 20.953  23.243  -70.697  1.00 47.38  ? 396  VAL C CA  1 
ATOM   10178 C C   . VAL C 1 403 ? 20.030  23.573  -69.521  1.00 49.16  ? 396  VAL C C   1 
ATOM   10179 O O   . VAL C 1 403 ? 20.420  23.256  -68.388  1.00 45.14  ? 396  VAL C O   1 
ATOM   10180 C CB  . VAL C 1 403 ? 21.768  24.458  -71.171  1.00 49.74  ? 396  VAL C CB  1 
ATOM   10181 C CG1 . VAL C 1 403 ? 22.286  25.305  -70.016  1.00 52.62  ? 396  VAL C CG1 1 
ATOM   10182 C CG2 . VAL C 1 403 ? 22.895  23.995  -72.077  1.00 48.92  ? 396  VAL C CG2 1 
ATOM   10183 N N   . ASP C 1 404 ? 18.867  24.179  -69.794  1.00 48.93  ? 397  ASP C N   1 
ATOM   10184 C CA  . ASP C 1 404 ? 17.863  24.564  -68.769  1.00 52.32  ? 397  ASP C CA  1 
ATOM   10185 C C   . ASP C 1 404 ? 16.453  24.393  -69.352  1.00 50.06  ? 397  ASP C C   1 
ATOM   10186 O O   . ASP C 1 404 ? 16.316  24.206  -70.581  1.00 47.18  ? 397  ASP C O   1 
ATOM   10187 C CB  . ASP C 1 404 ? 18.132  25.973  -68.236  1.00 58.24  ? 397  ASP C CB  1 
ATOM   10188 C CG  . ASP C 1 404 ? 17.821  27.096  -69.213  1.00 65.67  ? 397  ASP C CG  1 
ATOM   10189 O OD1 . ASP C 1 404 ? 16.751  27.039  -69.876  1.00 70.96  ? 397  ASP C OD1 1 
ATOM   10190 O OD2 . ASP C 1 404 ? 18.651  28.029  -69.294  1.00 72.63  ? 397  ASP C OD2 1 
ATOM   10191 N N   A ASN C 1 405 ? 15.439  24.471  -68.485  0.50 50.04  ? 398  ASN C N   1 
ATOM   10192 N N   B ASN C 1 405 ? 15.440  24.458  -68.482  0.50 48.30  ? 398  ASN C N   1 
ATOM   10193 C CA  A ASN C 1 405 ? 14.035  24.135  -68.830  0.50 50.50  ? 398  ASN C CA  1 
ATOM   10194 C CA  B ASN C 1 405 ? 14.023  24.146  -68.805  0.50 47.63  ? 398  ASN C CA  1 
ATOM   10195 C C   A ASN C 1 405 ? 13.517  25.112  -69.887  0.50 49.79  ? 398  ASN C C   1 
ATOM   10196 C C   B ASN C 1 405 ? 13.513  25.114  -69.877  0.50 48.15  ? 398  ASN C C   1 
ATOM   10197 O O   A ASN C 1 405 ? 12.897  24.625  -70.853  0.50 48.04  ? 398  ASN C O   1 
ATOM   10198 O O   B ASN C 1 405 ? 12.893  24.629  -70.847  0.50 46.41  ? 398  ASN C O   1 
ATOM   10199 C CB  A ASN C 1 405 ? 13.121  24.099  -67.607  0.50 50.60  ? 398  ASN C CB  1 
ATOM   10200 C CB  B ASN C 1 405 ? 13.156  24.166  -67.545  0.50 45.99  ? 398  ASN C CB  1 
ATOM   10201 C CG  A ASN C 1 405 ? 12.016  23.071  -67.746  0.50 52.50  ? 398  ASN C CG  1 
ATOM   10202 C CG  B ASN C 1 405 ? 13.822  24.942  -66.428  0.50 45.46  ? 398  ASN C CG  1 
ATOM   10203 O OD1 A ASN C 1 405 ? 11.843  22.439  -68.788  0.50 47.33  ? 398  ASN C OD1 1 
ATOM   10204 O OD1 B ASN C 1 405 ? 13.460  26.086  -66.175  0.50 47.37  ? 398  ASN C OD1 1 
ATOM   10205 N ND2 A ASN C 1 405 ? 11.259  22.884  -66.681  0.50 58.35  ? 398  ASN C ND2 1 
ATOM   10206 N ND2 B ASN C 1 405 ? 14.823  24.352  -65.790  0.50 42.68  ? 398  ASN C ND2 1 
ATOM   10207 N N   . GLU C 1 406 ? 13.771  26.415  -69.710  1.00 50.36  ? 399  GLU C N   1 
ATOM   10208 C CA  . GLU C 1 406 ? 13.208  27.487  -70.578  1.00 57.96  ? 399  GLU C CA  1 
ATOM   10209 C C   . GLU C 1 406 ? 13.698  27.325  -72.028  1.00 54.22  ? 399  GLU C C   1 
ATOM   10210 O O   . GLU C 1 406 ? 12.924  27.657  -72.955  1.00 45.63  ? 399  GLU C O   1 
ATOM   10211 C CB  . GLU C 1 406 ? 13.559  28.874  -70.050  1.00 71.28  ? 399  GLU C CB  1 
ATOM   10212 C CG  . GLU C 1 406 ? 12.904  29.979  -70.861  1.00 88.13  ? 399  GLU C CG  1 
ATOM   10213 C CD  . GLU C 1 406 ? 12.874  31.346  -70.203  1.00 99.54  ? 399  GLU C CD  1 
ATOM   10214 O OE1 . GLU C 1 406 ? 13.835  31.681  -69.472  1.00 108.38 ? 399  GLU C OE1 1 
ATOM   10215 O OE2 . GLU C 1 406 ? 11.892  32.087  -70.438  1.00 105.51 ? 399  GLU C OE2 1 
ATOM   10216 N N   . ILE C 1 407 ? 14.932  26.847  -72.210  1.00 49.49  ? 400  ILE C N   1 
ATOM   10217 C CA  . ILE C 1 407 ? 15.533  26.567  -73.548  1.00 46.91  ? 400  ILE C CA  1 
ATOM   10218 C C   . ILE C 1 407 ? 14.777  25.399  -74.211  1.00 46.64  ? 400  ILE C C   1 
ATOM   10219 O O   . ILE C 1 407 ? 14.439  25.538  -75.398  1.00 39.18  ? 400  ILE C O   1 
ATOM   10220 C CB  . ILE C 1 407 ? 17.044  26.295  -73.411  1.00 46.70  ? 400  ILE C CB  1 
ATOM   10221 C CG1 . ILE C 1 407 ? 17.812  27.567  -73.037  1.00 48.52  ? 400  ILE C CG1 1 
ATOM   10222 C CG2 . ILE C 1 407 ? 17.603  25.644  -74.664  1.00 43.69  ? 400  ILE C CG2 1 
ATOM   10223 C CD1 . ILE C 1 407 ? 19.246  27.312  -72.608  1.00 50.35  ? 400  ILE C CD1 1 
ATOM   10224 N N   . GLY C 1 408 ? 14.517  24.307  -73.469  1.00 49.24  ? 401  GLY C N   1 
ATOM   10225 C CA  . GLY C 1 408 ? 13.708  23.152  -73.920  1.00 47.84  ? 401  GLY C CA  1 
ATOM   10226 C C   . GLY C 1 408 ? 12.350  23.591  -74.456  1.00 46.59  ? 401  GLY C C   1 
ATOM   10227 O O   . GLY C 1 408 ? 11.931  23.089  -75.517  1.00 44.03  ? 401  GLY C O   1 
ATOM   10228 N N   . TYR C 1 409 ? 11.701  24.539  -73.777  1.00 48.90  ? 402  TYR C N   1 
ATOM   10229 C CA  . TYR C 1 409 ? 10.372  25.082  -74.153  1.00 53.42  ? 402  TYR C CA  1 
ATOM   10230 C C   . TYR C 1 409 ? 10.522  25.908  -75.434  1.00 48.88  ? 402  TYR C C   1 
ATOM   10231 O O   . TYR C 1 409 ? 9.637   25.835  -76.297  1.00 47.65  ? 402  TYR C O   1 
ATOM   10232 C CB  . TYR C 1 409 ? 9.751   25.934  -73.038  1.00 62.20  ? 402  TYR C CB  1 
ATOM   10233 C CG  . TYR C 1 409 ? 9.596   25.274  -71.685  1.00 74.57  ? 402  TYR C CG  1 
ATOM   10234 C CD1 . TYR C 1 409 ? 9.312   23.919  -71.569  1.00 81.41  ? 402  TYR C CD1 1 
ATOM   10235 C CD2 . TYR C 1 409 ? 9.708   26.012  -70.507  1.00 80.94  ? 402  TYR C CD2 1 
ATOM   10236 C CE1 . TYR C 1 409 ? 9.161   23.315  -70.327  1.00 88.97  ? 402  TYR C CE1 1 
ATOM   10237 C CE2 . TYR C 1 409 ? 9.573   25.419  -69.257  1.00 80.37  ? 402  TYR C CE2 1 
ATOM   10238 C CZ  . TYR C 1 409 ? 9.292   24.066  -69.169  1.00 85.21  ? 402  TYR C CZ  1 
ATOM   10239 O OH  . TYR C 1 409 ? 9.134   23.461  -67.959  1.00 78.08  ? 402  TYR C OH  1 
ATOM   10240 N N   . ASN C 1 410 ? 11.604  26.675  -75.554  1.00 47.40  ? 403  ASN C N   1 
ATOM   10241 C CA  . ASN C 1 410 ? 11.839  27.529  -76.747  1.00 48.64  ? 403  ASN C CA  1 
ATOM   10242 C C   . ASN C 1 410 ? 12.021  26.647  -77.982  1.00 42.62  ? 403  ASN C C   1 
ATOM   10243 O O   . ASN C 1 410 ? 11.561  27.057  -79.063  1.00 38.07  ? 403  ASN C O   1 
ATOM   10244 C CB  . ASN C 1 410 ? 13.022  28.470  -76.549  1.00 52.37  ? 403  ASN C CB  1 
ATOM   10245 C CG  . ASN C 1 410 ? 12.668  29.582  -75.589  1.00 61.56  ? 403  ASN C CG  1 
ATOM   10246 O OD1 . ASN C 1 410 ? 11.549  30.103  -75.617  1.00 64.60  ? 403  ASN C OD1 1 
ATOM   10247 N ND2 . ASN C 1 410 ? 13.597  29.915  -74.706  1.00 68.76  ? 403  ASN C ND2 1 
ATOM   10248 N N   . PHE C 1 411 ? 12.638  25.476  -77.808  1.00 38.14  ? 404  PHE C N   1 
ATOM   10249 C CA  . PHE C 1 411 ? 12.877  24.486  -78.885  1.00 37.20  ? 404  PHE C CA  1 
ATOM   10250 C C   . PHE C 1 411 ? 11.552  23.881  -79.340  1.00 37.14  ? 404  PHE C C   1 
ATOM   10251 O O   . PHE C 1 411 ? 11.292  23.871  -80.537  1.00 39.56  ? 404  PHE C O   1 
ATOM   10252 C CB  . PHE C 1 411 ? 13.804  23.373  -78.406  1.00 37.39  ? 404  PHE C CB  1 
ATOM   10253 C CG  . PHE C 1 411 ? 14.111  22.338  -79.454  1.00 36.97  ? 404  PHE C CG  1 
ATOM   10254 C CD1 . PHE C 1 411 ? 15.046  22.579  -80.445  1.00 36.49  ? 404  PHE C CD1 1 
ATOM   10255 C CD2 . PHE C 1 411 ? 13.473  21.113  -79.436  1.00 36.66  ? 404  PHE C CD2 1 
ATOM   10256 C CE1 . PHE C 1 411 ? 15.340  21.616  -81.393  1.00 34.66  ? 404  PHE C CE1 1 
ATOM   10257 C CE2 . PHE C 1 411 ? 13.781  20.142  -80.375  1.00 37.22  ? 404  PHE C CE2 1 
ATOM   10258 C CZ  . PHE C 1 411 ? 14.714  20.397  -81.352  1.00 34.49  ? 404  PHE C CZ  1 
ATOM   10259 N N   . ALA C 1 412 ? 10.745  23.380  -78.405  1.00 39.23  ? 405  ALA C N   1 
ATOM   10260 C CA  . ALA C 1 412 ? 9.396   22.837  -78.694  1.00 37.77  ? 405  ALA C CA  1 
ATOM   10261 C C   . ALA C 1 412 ? 8.617   23.849  -79.539  1.00 38.23  ? 405  ALA C C   1 
ATOM   10262 O O   . ALA C 1 412 ? 8.011   23.399  -80.525  1.00 43.66  ? 405  ALA C O   1 
ATOM   10263 C CB  . ALA C 1 412 ? 8.663   22.499  -77.418  1.00 38.56  ? 405  ALA C CB  1 
ATOM   10264 N N   . SER C 1 413 ? 8.660   25.147  -79.187  1.00 38.21  ? 406  SER C N   1 
ATOM   10265 C CA  . SER C 1 413 ? 7.918   26.251  -79.869  1.00 38.70  ? 406  SER C CA  1 
ATOM   10266 C C   . SER C 1 413 ? 8.475   26.457  -81.267  1.00 37.85  ? 406  SER C C   1 
ATOM   10267 O O   . SER C 1 413 ? 7.685   26.525  -82.181  1.00 35.13  ? 406  SER C O   1 
ATOM   10268 C CB  . SER C 1 413 ? 7.974   27.563  -79.148  1.00 39.64  ? 406  SER C CB  1 
ATOM   10269 O OG  . SER C 1 413 ? 7.879   27.363  -77.756  1.00 53.07  ? 406  SER C OG  1 
ATOM   10270 N N   . GLU C 1 414 ? 9.791   26.596  -81.379  1.00 40.40  ? 407  GLU C N   1 
ATOM   10271 C CA  . GLU C 1 414 ? 10.492  26.812  -82.671  1.00 43.05  ? 407  GLU C CA  1 
ATOM   10272 C C   . GLU C 1 414 ? 10.146  25.665  -83.622  1.00 41.42  ? 407  GLU C C   1 
ATOM   10273 O O   . GLU C 1 414 ? 9.769   25.960  -84.772  1.00 46.16  ? 407  GLU C O   1 
ATOM   10274 C CB  . GLU C 1 414 ? 11.997  26.976  -82.455  1.00 43.86  ? 407  GLU C CB  1 
ATOM   10275 C CG  . GLU C 1 414 ? 12.396  28.409  -82.144  1.00 48.99  ? 407  GLU C CG  1 
ATOM   10276 C CD  . GLU C 1 414 ? 11.898  29.424  -83.161  1.00 59.27  ? 407  GLU C CD  1 
ATOM   10277 O OE1 . GLU C 1 414 ? 11.918  29.104  -84.392  1.00 62.65  ? 407  GLU C OE1 1 
ATOM   10278 O OE2 . GLU C 1 414 ? 11.453  30.509  -82.718  1.00 68.10  ? 407  GLU C OE2 1 
ATOM   10279 N N   . MET C 1 415 ? 10.200  24.420  -83.147  1.00 37.70  ? 408  MET C N   1 
ATOM   10280 C CA  . MET C 1 415 ? 9.835   23.217  -83.944  1.00 37.20  ? 408  MET C CA  1 
ATOM   10281 C C   . MET C 1 415 ? 8.368   23.288  -84.389  1.00 37.32  ? 408  MET C C   1 
ATOM   10282 O O   . MET C 1 415 ? 8.076   22.998  -85.561  1.00 40.09  ? 408  MET C O   1 
ATOM   10283 C CB  . MET C 1 415 ? 10.054  21.944  -83.129  1.00 34.83  ? 408  MET C CB  1 
ATOM   10284 C CG  . MET C 1 415 ? 11.511  21.634  -82.938  1.00 34.74  ? 408  MET C CG  1 
ATOM   10285 S SD  . MET C 1 415 ? 12.391  21.321  -84.484  1.00 33.39  ? 408  MET C SD  1 
ATOM   10286 C CE  . MET C 1 415 ? 12.222  19.536  -84.576  1.00 34.23  ? 408  MET C CE  1 
ATOM   10287 N N   . PHE C 1 416 ? 7.473   23.662  -83.483  1.00 38.57  ? 409  PHE C N   1 
ATOM   10288 C CA  . PHE C 1 416 ? 6.022   23.802  -83.761  1.00 41.16  ? 409  PHE C CA  1 
ATOM   10289 C C   . PHE C 1 416 ? 5.822   24.898  -84.811  1.00 38.14  ? 409  PHE C C   1 
ATOM   10290 O O   . PHE C 1 416 ? 4.970   24.718  -85.696  1.00 34.98  ? 409  PHE C O   1 
ATOM   10291 C CB  . PHE C 1 416 ? 5.269   24.098  -82.458  1.00 41.88  ? 409  PHE C CB  1 
ATOM   10292 C CG  . PHE C 1 416 ? 3.774   23.995  -82.555  1.00 43.49  ? 409  PHE C CG  1 
ATOM   10293 C CD1 . PHE C 1 416 ? 3.140   22.788  -82.320  1.00 44.98  ? 409  PHE C CD1 1 
ATOM   10294 C CD2 . PHE C 1 416 ? 3.005   25.103  -82.871  1.00 45.61  ? 409  PHE C CD2 1 
ATOM   10295 C CE1 . PHE C 1 416 ? 1.763   22.686  -82.408  1.00 45.51  ? 409  PHE C CE1 1 
ATOM   10296 C CE2 . PHE C 1 416 ? 1.624   25.000  -82.967  1.00 46.25  ? 409  PHE C CE2 1 
ATOM   10297 C CZ  . PHE C 1 416 ? 1.007   23.791  -82.736  1.00 46.07  ? 409  PHE C CZ  1 
ATOM   10298 N N   . ARG C 1 417 ? 6.582   25.997  -84.716  1.00 39.07  ? 410  ARG C N   1 
ATOM   10299 C CA  . ARG C 1 417 ? 6.500   27.128  -85.670  1.00 44.60  ? 410  ARG C CA  1 
ATOM   10300 C C   . ARG C 1 417 ? 6.796   26.580  -87.062  1.00 42.89  ? 410  ARG C C   1 
ATOM   10301 O O   . ARG C 1 417 ? 6.170   27.062  -88.023  1.00 39.86  ? 410  ARG C O   1 
ATOM   10302 C CB  . ARG C 1 417 ? 7.438   28.266  -85.254  1.00 52.17  ? 410  ARG C CB  1 
ATOM   10303 C CG  . ARG C 1 417 ? 7.653   29.381  -86.264  1.00 66.32  ? 410  ARG C CG  1 
ATOM   10304 C CD  . ARG C 1 417 ? 8.480   30.488  -85.610  1.00 81.87  ? 410  ARG C CD  1 
ATOM   10305 N NE  . ARG C 1 417 ? 8.887   31.546  -86.525  1.00 95.23  ? 410  ARG C NE  1 
ATOM   10306 C CZ  . ARG C 1 417 ? 9.500   32.672  -86.157  1.00 105.58 ? 410  ARG C CZ  1 
ATOM   10307 N NH1 . ARG C 1 417 ? 9.828   33.575  -87.068  1.00 113.80 ? 410  ARG C NH1 1 
ATOM   10308 N NH2 . ARG C 1 417 ? 9.778   32.907  -84.885  1.00 102.43 ? 410  ARG C NH2 1 
ATOM   10309 N N   . GLN C 1 418 ? 7.650   25.559  -87.139  1.00 41.27  ? 411  GLN C N   1 
ATOM   10310 C CA  . GLN C 1 418 ? 8.095   24.944  -88.413  1.00 41.60  ? 411  GLN C CA  1 
ATOM   10311 C C   . GLN C 1 418 ? 7.289   23.671  -88.710  1.00 41.47  ? 411  GLN C C   1 
ATOM   10312 O O   . GLN C 1 418 ? 7.722   22.896  -89.572  1.00 41.33  ? 411  GLN C O   1 
ATOM   10313 C CB  . GLN C 1 418 ? 9.594   24.683  -88.325  1.00 42.12  ? 411  GLN C CB  1 
ATOM   10314 C CG  . GLN C 1 418 ? 10.396  25.957  -88.145  1.00 44.21  ? 411  GLN C CG  1 
ATOM   10315 C CD  . GLN C 1 418 ? 11.857  25.621  -88.008  1.00 47.20  ? 411  GLN C CD  1 
ATOM   10316 O OE1 . GLN C 1 418 ? 12.485  25.170  -88.963  1.00 47.02  ? 411  GLN C OE1 1 
ATOM   10317 N NE2 . GLN C 1 418 ? 12.397  25.822  -86.809  1.00 47.93  ? 411  GLN C NE2 1 
ATOM   10318 N N   . ARG C 1 419 ? 6.163   23.476  -88.029  1.00 42.18  ? 412  ARG C N   1 
ATOM   10319 C CA  . ARG C 1 419 ? 5.198   22.374  -88.285  1.00 41.62  ? 412  ARG C CA  1 
ATOM   10320 C C   . ARG C 1 419 ? 5.877   21.017  -88.064  1.00 36.05  ? 412  ARG C C   1 
ATOM   10321 O O   . ARG C 1 419 ? 5.622   20.077  -88.835  1.00 34.43  ? 412  ARG C O   1 
ATOM   10322 C CB  . ARG C 1 419 ? 4.586   22.511  -89.688  1.00 48.43  ? 412  ARG C CB  1 
ATOM   10323 C CG  . ARG C 1 419 ? 3.778   23.781  -89.928  1.00 53.46  ? 412  ARG C CG  1 
ATOM   10324 C CD  . ARG C 1 419 ? 3.146   24.278  -88.655  1.00 57.83  ? 412  ARG C CD  1 
ATOM   10325 N NE  . ARG C 1 419 ? 2.255   25.422  -88.749  1.00 66.29  ? 412  ARG C NE  1 
ATOM   10326 C CZ  . ARG C 1 419 ? 2.053   26.304  -87.766  1.00 74.52  ? 412  ARG C CZ  1 
ATOM   10327 N NH1 . ARG C 1 419 ? 2.676   26.175  -86.612  1.00 74.79  ? 412  ARG C NH1 1 
ATOM   10328 N NH2 . ARG C 1 419 ? 1.206   27.310  -87.921  1.00 77.42  ? 412  ARG C NH2 1 
ATOM   10329 N N   . VAL C 1 420 ? 6.693   20.921  -87.017  1.00 33.52  ? 413  VAL C N   1 
ATOM   10330 C CA  . VAL C 1 420 ? 7.208   19.624  -86.498  1.00 33.21  ? 413  VAL C CA  1 
ATOM   10331 C C   . VAL C 1 420 ? 6.801   19.513  -85.033  1.00 34.10  ? 413  VAL C C   1 
ATOM   10332 O O   . VAL C 1 420 ? 7.114   20.424  -84.237  1.00 32.95  ? 413  VAL C O   1 
ATOM   10333 C CB  . VAL C 1 420 ? 8.725   19.472  -86.659  1.00 32.90  ? 413  VAL C CB  1 
ATOM   10334 C CG1 . VAL C 1 420 ? 9.193   18.129  -86.114  1.00 33.86  ? 413  VAL C CG1 1 
ATOM   10335 C CG2 . VAL C 1 420 ? 9.151   19.659  -88.108  1.00 33.15  ? 413  VAL C CG2 1 
ATOM   10336 N N   . LEU C 1 421 ? 6.147   18.405  -84.710  1.00 34.04  ? 414  LEU C N   1 
ATOM   10337 C CA  . LEU C 1 421 ? 5.471   18.192  -83.416  1.00 35.65  ? 414  LEU C CA  1 
ATOM   10338 C C   . LEU C 1 421 ? 6.399   17.382  -82.517  1.00 36.05  ? 414  LEU C C   1 
ATOM   10339 O O   . LEU C 1 421 ? 6.665   16.221  -82.834  1.00 34.67  ? 414  LEU C O   1 
ATOM   10340 C CB  . LEU C 1 421 ? 4.153   17.468  -83.684  1.00 38.00  ? 414  LEU C CB  1 
ATOM   10341 C CG  . LEU C 1 421 ? 3.203   17.364  -82.501  1.00 41.31  ? 414  LEU C CG  1 
ATOM   10342 C CD1 . LEU C 1 421 ? 2.973   18.718  -81.845  1.00 43.55  ? 414  LEU C CD1 1 
ATOM   10343 C CD2 . LEU C 1 421 ? 1.893   16.749  -82.944  1.00 41.53  ? 414  LEU C CD2 1 
ATOM   10344 N N   . VAL C 1 422 ? 6.880   18.014  -81.449  1.00 36.22  ? 415  VAL C N   1 
ATOM   10345 C CA  . VAL C 1 422 ? 7.625   17.384  -80.325  1.00 35.17  ? 415  VAL C CA  1 
ATOM   10346 C C   . VAL C 1 422 ? 6.977   17.883  -79.040  1.00 36.00  ? 415  VAL C C   1 
ATOM   10347 O O   . VAL C 1 422 ? 6.200   18.859  -79.112  1.00 40.87  ? 415  VAL C O   1 
ATOM   10348 C CB  . VAL C 1 422 ? 9.108   17.776  -80.378  1.00 35.44  ? 415  VAL C CB  1 
ATOM   10349 C CG1 . VAL C 1 422 ? 9.758   17.288  -81.663  1.00 35.49  ? 415  VAL C CG1 1 
ATOM   10350 C CG2 . VAL C 1 422 ? 9.285   19.280  -80.210  1.00 35.32  ? 415  VAL C CG2 1 
ATOM   10351 N N   . ALA C 1 423 ? 7.302   17.289  -77.899  1.00 35.11  ? 416  ALA C N   1 
ATOM   10352 C CA  . ALA C 1 423 ? 6.848   17.830  -76.604  1.00 34.69  ? 416  ALA C CA  1 
ATOM   10353 C C   . ALA C 1 423 ? 7.776   17.348  -75.515  1.00 35.09  ? 416  ALA C C   1 
ATOM   10354 O O   . ALA C 1 423 ? 8.617   16.503  -75.823  1.00 38.41  ? 416  ALA C O   1 
ATOM   10355 C CB  . ALA C 1 423 ? 5.431   17.416  -76.347  1.00 35.34  ? 416  ALA C CB  1 
ATOM   10356 N N   . GLY C 1 424 ? 7.584   17.861  -74.302  1.00 39.03  ? 417  GLY C N   1 
ATOM   10357 C CA  . GLY C 1 424 ? 8.380   17.501  -73.115  1.00 42.54  ? 417  GLY C CA  1 
ATOM   10358 C C   . GLY C 1 424 ? 8.067   16.109  -72.587  1.00 46.59  ? 417  GLY C C   1 
ATOM   10359 O O   . GLY C 1 424 ? 7.007   15.530  -72.960  1.00 47.07  ? 417  GLY C O   1 
ATOM   10360 N N   . THR C 1 425 ? 8.972   15.597  -71.745  1.00 55.14  ? 418  THR C N   1 
ATOM   10361 C CA  . THR C 1 425 ? 8.834   14.348  -70.947  1.00 61.61  ? 418  THR C CA  1 
ATOM   10362 C C   . THR C 1 425 ? 8.213   14.697  -69.582  1.00 63.07  ? 418  THR C C   1 
ATOM   10363 O O   . THR C 1 425 ? 8.303   15.883  -69.164  1.00 62.77  ? 418  THR C O   1 
ATOM   10364 C CB  . THR C 1 425 ? 10.182  13.612  -70.823  1.00 63.65  ? 418  THR C CB  1 
ATOM   10365 O OG1 . THR C 1 425 ? 11.180  14.525  -70.365  1.00 59.00  ? 418  THR C OG1 1 
ATOM   10366 C CG2 . THR C 1 425 ? 10.652  12.987  -72.124  1.00 63.78  ? 418  THR C CG2 1 
ATOM   10367 N N   . LEU C 1 426 ? 7.593   13.705  -68.922  1.00 64.76  ? 419  LEU C N   1 
ATOM   10368 C CA  . LEU C 1 426 ? 6.889   13.875  -67.620  1.00 64.12  ? 419  LEU C CA  1 
ATOM   10369 C C   . LEU C 1 426 ? 7.935   13.928  -66.485  1.00 64.66  ? 419  LEU C C   1 
ATOM   10370 O O   . LEU C 1 426 ? 8.124   15.030  -65.917  1.00 67.14  ? 419  LEU C O   1 
ATOM   10371 C CB  . LEU C 1 426 ? 5.843   12.760  -67.438  1.00 66.18  ? 419  LEU C CB  1 
ATOM   10372 C CG  . LEU C 1 426 ? 4.514   12.915  -68.205  1.00 70.40  ? 419  LEU C CG  1 
ATOM   10373 C CD1 . LEU C 1 426 ? 3.618   11.680  -68.059  1.00 69.81  ? 419  LEU C CD1 1 
ATOM   10374 C CD2 . LEU C 1 426 ? 3.734   14.147  -67.761  1.00 72.37  ? 419  LEU C CD2 1 
ATOM   10375 N N   . ASN C 1 427 ? 8.659   12.834  -66.208  1.00 62.14  ? 420  ASN C N   1 
ATOM   10376 C CA  . ASN C 1 427 ? 9.574   12.741  -65.033  1.00 65.92  ? 420  ASN C CA  1 
ATOM   10377 C C   . ASN C 1 427 ? 10.945  13.344  -65.366  1.00 65.97  ? 420  ASN C C   1 
ATOM   10378 O O   . ASN C 1 427 ? 11.958  12.797  -64.870  1.00 70.78  ? 420  ASN C O   1 
ATOM   10379 C CB  . ASN C 1 427 ? 9.745   11.299  -64.540  1.00 65.91  ? 420  ASN C CB  1 
ATOM   10380 C CG  . ASN C 1 427 ? 8.424   10.634  -64.246  1.00 66.28  ? 420  ASN C CG  1 
ATOM   10381 O OD1 . ASN C 1 427 ? 7.382   11.135  -64.657  1.00 66.22  ? 420  ASN C OD1 1 
ATOM   10382 N ND2 . ASN C 1 427 ? 8.460   9.525   -63.527  1.00 67.80  ? 420  ASN C ND2 1 
ATOM   10383 N N   . ASN C 1 428 ? 10.980  14.421  -66.161  1.00 62.17  ? 421  ASN C N   1 
ATOM   10384 C CA  . ASN C 1 428 ? 12.235  15.077  -66.613  1.00 58.13  ? 421  ASN C CA  1 
ATOM   10385 C C   . ASN C 1 428 ? 11.900  16.393  -67.323  1.00 63.41  ? 421  ASN C C   1 
ATOM   10386 O O   . ASN C 1 428 ? 11.392  16.341  -68.466  1.00 77.15  ? 421  ASN C O   1 
ATOM   10387 C CB  . ASN C 1 428 ? 13.069  14.161  -67.515  1.00 55.15  ? 421  ASN C CB  1 
ATOM   10388 C CG  . ASN C 1 428 ? 14.511  14.612  -67.680  1.00 57.39  ? 421  ASN C CG  1 
ATOM   10389 O OD1 . ASN C 1 428 ? 14.862  15.754  -67.393  1.00 54.02  ? 421  ASN C OD1 1 
ATOM   10390 N ND2 . ASN C 1 428 ? 15.372  13.720  -68.145  1.00 57.30  ? 421  ASN C ND2 1 
ATOM   10391 N N   . ALA C 1 429 ? 12.195  17.521  -66.668  1.00 69.88  ? 422  ALA C N   1 
ATOM   10392 C CA  . ALA C 1 429 ? 12.093  18.892  -67.222  1.00 73.98  ? 422  ALA C CA  1 
ATOM   10393 C C   . ALA C 1 429 ? 13.199  19.099  -68.267  1.00 77.15  ? 422  ALA C C   1 
ATOM   10394 O O   . ALA C 1 429 ? 14.144  18.280  -68.280  1.00 84.04  ? 422  ALA C O   1 
ATOM   10395 C CB  . ALA C 1 429 ? 12.208  19.899  -66.092  1.00 74.99  ? 422  ALA C CB  1 
ATOM   10396 N N   . LYS C 1 430 ? 13.111  20.133  -69.114  1.00 74.76  ? 423  LYS C N   1 
ATOM   10397 C CA  . LYS C 1 430 ? 14.235  20.602  -69.994  1.00 67.86  ? 423  LYS C CA  1 
ATOM   10398 C C   . LYS C 1 430 ? 14.644  19.521  -71.015  1.00 57.32  ? 423  LYS C C   1 
ATOM   10399 O O   . LYS C 1 430 ? 15.661  19.732  -71.704  1.00 56.66  ? 423  LYS C O   1 
ATOM   10400 C CB  . LYS C 1 430 ? 15.435  21.066  -69.147  1.00 67.43  ? 423  LYS C CB  1 
ATOM   10401 C CG  . LYS C 1 430 ? 16.427  19.996  -68.683  1.00 64.60  ? 423  LYS C CG  1 
ATOM   10402 C CD  . LYS C 1 430 ? 17.065  20.221  -67.312  1.00 64.17  ? 423  LYS C CD  1 
ATOM   10403 C CE  . LYS C 1 430 ? 18.423  20.888  -67.301  1.00 72.10  ? 423  LYS C CE  1 
ATOM   10404 N NZ  . LYS C 1 430 ? 19.485  20.085  -67.968  1.00 76.05  ? 423  LYS C NZ  1 
ATOM   10405 N N   . THR C 1 431 ? 13.883  18.422  -71.115  1.00 47.48  ? 424  THR C N   1 
ATOM   10406 C CA  . THR C 1 431 ? 14.154  17.254  -71.999  1.00 39.85  ? 424  THR C CA  1 
ATOM   10407 C C   . THR C 1 431 ? 12.981  17.109  -72.975  1.00 34.97  ? 424  THR C C   1 
ATOM   10408 O O   . THR C 1 431 ? 11.815  17.043  -72.519  1.00 30.01  ? 424  THR C O   1 
ATOM   10409 C CB  . THR C 1 431 ? 14.424  15.993  -71.172  1.00 37.40  ? 424  THR C CB  1 
ATOM   10410 O OG1 . THR C 1 431 ? 15.579  16.308  -70.407  1.00 37.47  ? 424  THR C OG1 1 
ATOM   10411 C CG2 . THR C 1 431 ? 14.711  14.748  -71.977  1.00 37.21  ? 424  THR C CG2 1 
ATOM   10412 N N   . ILE C 1 432 ? 13.285  17.091  -74.274  1.00 33.67  ? 425  ILE C N   1 
ATOM   10413 C CA  . ILE C 1 432 ? 12.280  16.955  -75.366  1.00 29.39  ? 425  ILE C CA  1 
ATOM   10414 C C   . ILE C 1 432 ? 12.379  15.540  -75.924  1.00 27.57  ? 425  ILE C C   1 
ATOM   10415 O O   . ILE C 1 432 ? 13.469  15.143  -76.297  1.00 24.45  ? 425  ILE C O   1 
ATOM   10416 C CB  . ILE C 1 432 ? 12.529  18.044  -76.415  1.00 29.50  ? 425  ILE C CB  1 
ATOM   10417 C CG1 . ILE C 1 432 ? 12.383  19.439  -75.805  1.00 29.90  ? 425  ILE C CG1 1 
ATOM   10418 C CG2 . ILE C 1 432 ? 11.626  17.863  -77.613  1.00 30.46  ? 425  ILE C CG2 1 
ATOM   10419 C CD1 . ILE C 1 432 ? 10.963  19.829  -75.466  1.00 29.97  ? 425  ILE C CD1 1 
ATOM   10420 N N   . ARG C 1 433 ? 11.275  14.802  -75.912  1.00 30.15  ? 426  ARG C N   1 
ATOM   10421 C CA  . ARG C 1 433 ? 11.171  13.447  -76.521  1.00 34.89  ? 426  ARG C CA  1 
ATOM   10422 C C   . ARG C 1 433 ? 11.076  13.592  -78.044  1.00 34.20  ? 426  ARG C C   1 
ATOM   10423 O O   . ARG C 1 433 ? 10.365  14.484  -78.534  1.00 39.08  ? 426  ARG C O   1 
ATOM   10424 C CB  . ARG C 1 433 ? 9.969   12.664  -75.963  1.00 38.85  ? 426  ARG C CB  1 
ATOM   10425 C CG  . ARG C 1 433 ? 8.593   13.166  -76.411  1.00 39.59  ? 426  ARG C CG  1 
ATOM   10426 C CD  . ARG C 1 433 ? 7.398   12.543  -75.684  1.00 39.17  ? 426  ARG C CD  1 
ATOM   10427 N NE  . ARG C 1 433 ? 7.689   12.280  -74.283  1.00 43.79  ? 426  ARG C NE  1 
ATOM   10428 C CZ  . ARG C 1 433 ? 7.388   11.164  -73.614  1.00 46.98  ? 426  ARG C CZ  1 
ATOM   10429 N NH1 . ARG C 1 433 ? 6.748   10.165  -74.192  1.00 42.77  ? 426  ARG C NH1 1 
ATOM   10430 N NH2 . ARG C 1 433 ? 7.747   11.037  -72.349  1.00 53.98  ? 426  ARG C NH2 1 
ATOM   10431 N N   . ILE C 1 434 ? 11.779  12.737  -78.764  1.00 30.60  ? 427  ILE C N   1 
ATOM   10432 C CA  . ILE C 1 434 ? 11.557  12.521  -80.214  1.00 30.21  ? 427  ILE C CA  1 
ATOM   10433 C C   . ILE C 1 434 ? 11.108  11.075  -80.357  1.00 27.50  ? 427  ILE C C   1 
ATOM   10434 O O   . ILE C 1 434 ? 11.939  10.166  -80.166  1.00 26.15  ? 427  ILE C O   1 
ATOM   10435 C CB  . ILE C 1 434 ? 12.838  12.824  -81.012  1.00 34.78  ? 427  ILE C CB  1 
ATOM   10436 C CG1 . ILE C 1 434 ? 13.415  14.200  -80.655  1.00 36.44  ? 427  ILE C CG1 1 
ATOM   10437 C CG2 . ILE C 1 434 ? 12.573  12.672  -82.506  1.00 35.21  ? 427  ILE C CG2 1 
ATOM   10438 C CD1 . ILE C 1 434 ? 12.582  15.360  -81.154  1.00 38.39  ? 427  ILE C CD1 1 
ATOM   10439 N N   . GLU C 1 435 ? 9.825   10.893  -80.628  1.00 27.32  ? 428  GLU C N   1 
ATOM   10440 C CA  . GLU C 1 435 ? 9.138   9.578   -80.656  1.00 27.95  ? 428  GLU C CA  1 
ATOM   10441 C C   . GLU C 1 435 ? 8.258   9.515   -81.899  1.00 23.89  ? 428  GLU C C   1 
ATOM   10442 O O   . GLU C 1 435 ? 7.037   9.423   -81.796  1.00 22.30  ? 428  GLU C O   1 
ATOM   10443 C CB  . GLU C 1 435 ? 8.289   9.403   -79.392  1.00 30.29  ? 428  GLU C CB  1 
ATOM   10444 C CG  . GLU C 1 435 ? 8.992   8.680   -78.271  1.00 34.97  ? 428  GLU C CG  1 
ATOM   10445 C CD  . GLU C 1 435 ? 8.044   8.317   -77.126  1.00 37.89  ? 428  GLU C CD  1 
ATOM   10446 O OE1 . GLU C 1 435 ? 7.319   7.293   -77.211  1.00 34.97  ? 428  GLU C OE1 1 
ATOM   10447 O OE2 . GLU C 1 435 ? 8.039   9.071   -76.142  1.00 44.29  ? 428  GLU C OE2 1 
ATOM   10448 N N   . PRO C 1 436 ? 8.831   9.573   -83.114  1.00 22.34  ? 429  PRO C N   1 
ATOM   10449 C CA  . PRO C 1 436 ? 8.024   9.592   -84.330  1.00 21.12  ? 429  PRO C CA  1 
ATOM   10450 C C   . PRO C 1 436 ? 7.438   8.214   -84.608  1.00 19.52  ? 429  PRO C C   1 
ATOM   10451 O O   . PRO C 1 436 ? 7.898   7.208   -84.082  1.00 19.51  ? 429  PRO C O   1 
ATOM   10452 C CB  . PRO C 1 436 ? 9.006   10.000  -85.446  1.00 20.83  ? 429  PRO C CB  1 
ATOM   10453 C CG  . PRO C 1 436 ? 10.318  10.296  -84.755  1.00 21.84  ? 429  PRO C CG  1 
ATOM   10454 C CD  . PRO C 1 436 ? 10.266  9.592   -83.412  1.00 22.26  ? 429  PRO C CD  1 
ATOM   10455 N N   . PRO C 1 437 ? 6.416   8.120   -85.477  1.00 18.93  ? 430  PRO C N   1 
ATOM   10456 C CA  . PRO C 1 437 ? 5.989   6.831   -86.014  1.00 18.23  ? 430  PRO C CA  1 
ATOM   10457 C C   . PRO C 1 437 ? 7.176   6.071   -86.595  1.00 17.65  ? 430  PRO C C   1 
ATOM   10458 O O   . PRO C 1 437 ? 7.991   6.708   -87.186  1.00 18.49  ? 430  PRO C O   1 
ATOM   10459 C CB  . PRO C 1 437 ? 5.015   7.225   -87.114  1.00 17.54  ? 430  PRO C CB  1 
ATOM   10460 C CG  . PRO C 1 437 ? 4.438   8.542   -86.631  1.00 17.71  ? 430  PRO C CG  1 
ATOM   10461 C CD  . PRO C 1 437 ? 5.598   9.240   -85.965  1.00 18.95  ? 430  PRO C CD  1 
ATOM   10462 N N   . LEU C 1 438 ? 7.225   4.748   -86.435  1.00 17.94  ? 431  LEU C N   1 
ATOM   10463 C CA  . LEU C 1 438 ? 8.304   3.901   -87.012  1.00 17.66  ? 431  LEU C CA  1 
ATOM   10464 C C   . LEU C 1 438 ? 8.252   4.048   -88.540  1.00 17.80  ? 431  LEU C C   1 
ATOM   10465 O O   . LEU C 1 438 ? 9.269   3.787   -89.192  1.00 19.12  ? 431  LEU C O   1 
ATOM   10466 C CB  . LEU C 1 438 ? 8.139   2.440   -86.571  1.00 17.78  ? 431  LEU C CB  1 
ATOM   10467 C CG  . LEU C 1 438 ? 7.943   2.209   -85.065  1.00 18.48  ? 431  LEU C CG  1 
ATOM   10468 C CD1 . LEU C 1 438 ? 8.182   0.753   -84.669  1.00 17.68  ? 431  LEU C CD1 1 
ATOM   10469 C CD2 . LEU C 1 438 ? 8.816   3.138   -84.247  1.00 18.42  ? 431  LEU C CD2 1 
ATOM   10470 N N   . THR C 1 439 ? 7.109   4.499   -89.071  1.00 18.25  ? 432  THR C N   1 
ATOM   10471 C CA  . THR C 1 439 ? 6.812   4.675   -90.514  1.00 17.63  ? 432  THR C CA  1 
ATOM   10472 C C   . THR C 1 439 ? 7.328   6.023   -91.027  1.00 17.44  ? 432  THR C C   1 
ATOM   10473 O O   . THR C 1 439 ? 7.187   6.277   -92.235  1.00 15.50  ? 432  THR C O   1 
ATOM   10474 C CB  . THR C 1 439 ? 5.307   4.542   -90.729  1.00 18.97  ? 432  THR C CB  1 
ATOM   10475 O OG1 . THR C 1 439 ? 4.661   5.472   -89.854  1.00 20.23  ? 432  THR C OG1 1 
ATOM   10476 C CG2 . THR C 1 439 ? 4.802   3.146   -90.435  1.00 19.42  ? 432  THR C CG2 1 
ATOM   10477 N N   . LEU C 1 440 ? 7.927   6.855   -90.171  1.00 17.52  ? 433  LEU C N   1 
ATOM   10478 C CA  . LEU C 1 440 ? 8.525   8.147   -90.613  1.00 17.91  ? 433  LEU C CA  1 
ATOM   10479 C C   . LEU C 1 440 ? 9.452   7.875   -91.795  1.00 18.11  ? 433  LEU C C   1 
ATOM   10480 O O   . LEU C 1 440 ? 10.282  6.973   -91.694  1.00 19.39  ? 433  LEU C O   1 
ATOM   10481 C CB  . LEU C 1 440 ? 9.288   8.813   -89.467  1.00 17.73  ? 433  LEU C CB  1 
ATOM   10482 C CG  . LEU C 1 440 ? 9.653   10.271  -89.738  1.00 17.90  ? 433  LEU C CG  1 
ATOM   10483 C CD1 . LEU C 1 440 ? 8.423   11.149  -89.694  1.00 18.73  ? 433  LEU C CD1 1 
ATOM   10484 C CD2 . LEU C 1 440 ? 10.669  10.785  -88.754  1.00 18.47  ? 433  LEU C CD2 1 
ATOM   10485 N N   . THR C 1 441 ? 9.308   8.607   -92.890  1.00 18.79  ? 434  THR C N   1 
ATOM   10486 C CA  . THR C 1 441 ? 10.103  8.358   -94.120  1.00 20.31  ? 434  THR C CA  1 
ATOM   10487 C C   . THR C 1 441 ? 11.504  8.930   -93.934  1.00 22.31  ? 434  THR C C   1 
ATOM   10488 O O   . THR C 1 441 ? 11.681  9.844   -93.112  1.00 26.05  ? 434  THR C O   1 
ATOM   10489 C CB  . THR C 1 441 ? 9.468   8.948   -95.388  1.00 19.09  ? 434  THR C CB  1 
ATOM   10490 O OG1 . THR C 1 441 ? 9.627   10.366  -95.349  1.00 18.32  ? 434  THR C OG1 1 
ATOM   10491 C CG2 . THR C 1 441 ? 8.012   8.568   -95.544  1.00 18.22  ? 434  THR C CG2 1 
ATOM   10492 N N   . ILE C 1 442 ? 12.449  8.429   -94.706  1.00 23.28  ? 435  ILE C N   1 
ATOM   10493 C CA  . ILE C 1 442 ? 13.854  8.903   -94.661  1.00 24.96  ? 435  ILE C CA  1 
ATOM   10494 C C   . ILE C 1 442 ? 13.852  10.397  -94.956  1.00 23.75  ? 435  ILE C C   1 
ATOM   10495 O O   . ILE C 1 442 ? 14.573  11.123  -94.285  1.00 24.52  ? 435  ILE C O   1 
ATOM   10496 C CB  . ILE C 1 442 ? 14.727  8.133   -95.661  1.00 28.09  ? 435  ILE C CB  1 
ATOM   10497 C CG1 . ILE C 1 442 ? 14.599  6.616   -95.476  1.00 30.78  ? 435  ILE C CG1 1 
ATOM   10498 C CG2 . ILE C 1 442 ? 16.175  8.612   -95.559  1.00 27.89  ? 435  ILE C CG2 1 
ATOM   10499 C CD1 . ILE C 1 442 ? 15.102  6.120   -94.124  1.00 33.45  ? 435  ILE C CD1 1 
ATOM   10500 N N   . GLU C 1 443 ? 13.066  10.837  -95.929  1.00 23.75  ? 436  GLU C N   1 
ATOM   10501 C CA  . GLU C 1 443 ? 12.985  12.275  -96.276  1.00 24.91  ? 436  GLU C CA  1 
ATOM   10502 C C   . GLU C 1 443 ? 12.485  13.045  -95.053  1.00 23.83  ? 436  GLU C C   1 
ATOM   10503 O O   . GLU C 1 443 ? 13.081  14.074  -94.750  1.00 24.78  ? 436  GLU C O   1 
ATOM   10504 C CB  . GLU C 1 443 ? 12.089  12.546  -97.485  1.00 26.51  ? 436  GLU C CB  1 
ATOM   10505 C CG  . GLU C 1 443 ? 12.652  12.009  -98.792  1.00 30.20  ? 436  GLU C CG  1 
ATOM   10506 C CD  . GLU C 1 443 ? 12.158  10.651  -99.269  1.00 32.81  ? 436  GLU C CD  1 
ATOM   10507 O OE1 . GLU C 1 443 ? 11.731  9.822   -98.416  1.00 31.30  ? 436  GLU C OE1 1 
ATOM   10508 O OE2 . GLU C 1 443 ? 12.175  10.436  -100.524 1.00 35.17  ? 436  GLU C OE2 1 
ATOM   10509 N N   . GLN C 1 444 ? 11.436  12.570  -94.381  1.00 23.21  ? 437  GLN C N   1 
ATOM   10510 C CA  . GLN C 1 444 ? 10.906  13.258  -93.173  1.00 23.40  ? 437  GLN C CA  1 
ATOM   10511 C C   . GLN C 1 444 ? 12.012  13.302  -92.114  1.00 23.21  ? 437  GLN C C   1 
ATOM   10512 O O   . GLN C 1 444 ? 12.248  14.396  -91.575  1.00 25.31  ? 437  GLN C O   1 
ATOM   10513 C CB  . GLN C 1 444 ? 9.606   12.613  -92.684  1.00 22.97  ? 437  GLN C CB  1 
ATOM   10514 C CG  . GLN C 1 444 ? 8.431   12.989  -93.572  1.00 22.16  ? 437  GLN C CG  1 
ATOM   10515 C CD  . GLN C 1 444 ? 7.227   12.090  -93.439  1.00 21.42  ? 437  GLN C CD  1 
ATOM   10516 O OE1 . GLN C 1 444 ? 7.323   10.894  -93.155  1.00 21.37  ? 437  GLN C OE1 1 
ATOM   10517 N NE2 . GLN C 1 444 ? 6.070   12.689  -93.655  1.00 20.38  ? 437  GLN C NE2 1 
ATOM   10518 N N   . CYS C 1 445 ? 12.687  12.178  -91.856  1.00 23.31  ? 438  CYS C N   1 
ATOM   10519 C CA  . CYS C 1 445 ? 13.839  12.117  -90.915  1.00 25.49  ? 438  CYS C CA  1 
ATOM   10520 C C   . CYS C 1 445 ? 14.772  13.305  -91.186  1.00 25.79  ? 438  CYS C C   1 
ATOM   10521 O O   . CYS C 1 445 ? 15.052  14.053  -90.245  1.00 26.23  ? 438  CYS C O   1 
ATOM   10522 C CB  . CYS C 1 445 ? 14.622  10.814  -91.030  1.00 27.06  ? 438  CYS C CB  1 
ATOM   10523 S SG  . CYS C 1 445 ? 13.750  9.344   -90.419  1.00 26.67  ? 438  CYS C SG  1 
ATOM   10524 N N   . GLU C 1 446 ? 15.195  13.493  -92.438  1.00 26.41  ? 439  GLU C N   1 
ATOM   10525 C CA  . GLU C 1 446 ? 16.112  14.589  -92.855  1.00 24.63  ? 439  GLU C CA  1 
ATOM   10526 C C   . GLU C 1 446 ? 15.464  15.951  -92.574  1.00 23.35  ? 439  GLU C C   1 
ATOM   10527 O O   . GLU C 1 446 ? 16.168  16.836  -92.064  1.00 20.53  ? 439  GLU C O   1 
ATOM   10528 C CB  . GLU C 1 446 ? 16.456  14.485  -94.339  1.00 23.79  ? 439  GLU C CB  1 
ATOM   10529 C CG  . GLU C 1 446 ? 17.350  13.316  -94.697  1.00 25.26  ? 439  GLU C CG  1 
ATOM   10530 C CD  . GLU C 1 446 ? 17.913  13.358  -96.128  1.00 25.55  ? 439  GLU C CD  1 
ATOM   10531 O OE1 . GLU C 1 446 ? 17.775  14.404  -96.826  1.00 23.66  ? 439  GLU C OE1 1 
ATOM   10532 O OE2 . GLU C 1 446 ? 18.505  12.340  -96.561  1.00 24.44  ? 439  GLU C OE2 1 
ATOM   10533 N N   . LEU C 1 447 ? 14.176  16.108  -92.890  1.00 21.95  ? 440  LEU C N   1 
ATOM   10534 C CA  . LEU C 1 447 ? 13.434  17.377  -92.669  1.00 24.02  ? 440  LEU C CA  1 
ATOM   10535 C C   . LEU C 1 447 ? 13.416  17.694  -91.177  1.00 25.22  ? 440  LEU C C   1 
ATOM   10536 O O   . LEU C 1 447 ? 13.534  18.888  -90.835  1.00 26.58  ? 440  LEU C O   1 
ATOM   10537 C CB  . LEU C 1 447 ? 12.004  17.264  -93.216  1.00 24.60  ? 440  LEU C CB  1 
ATOM   10538 C CG  . LEU C 1 447 ? 11.922  17.175  -94.742  1.00 24.79  ? 440  LEU C CG  1 
ATOM   10539 C CD1 . LEU C 1 447 ? 10.483  17.068  -95.226  1.00 25.88  ? 440  LEU C CD1 1 
ATOM   10540 C CD2 . LEU C 1 447 ? 12.619  18.369  -95.395  1.00 24.61  ? 440  LEU C CD2 1 
ATOM   10541 N N   . VAL C 1 448 ? 13.277  16.665  -90.335  1.00 26.16  ? 441  VAL C N   1 
ATOM   10542 C CA  . VAL C 1 448 ? 13.232  16.805  -88.848  1.00 27.40  ? 441  VAL C CA  1 
ATOM   10543 C C   . VAL C 1 448 ? 14.562  17.409  -88.384  1.00 26.53  ? 441  VAL C C   1 
ATOM   10544 O O   . VAL C 1 448 ? 14.551  18.419  -87.670  1.00 25.93  ? 441  VAL C O   1 
ATOM   10545 C CB  . VAL C 1 448 ? 12.923  15.455  -88.170  1.00 28.15  ? 441  VAL C CB  1 
ATOM   10546 C CG1 . VAL C 1 448 ? 13.205  15.476  -86.682  1.00 29.49  ? 441  VAL C CG1 1 
ATOM   10547 C CG2 . VAL C 1 448 ? 11.493  15.016  -88.429  1.00 28.71  ? 441  VAL C CG2 1 
ATOM   10548 N N   . ILE C 1 449 ? 15.672  16.842  -88.838  1.00 27.38  ? 442  ILE C N   1 
ATOM   10549 C CA  . ILE C 1 449 ? 17.041  17.298  -88.478  1.00 26.25  ? 442  ILE C CA  1 
ATOM   10550 C C   . ILE C 1 449 ? 17.225  18.744  -88.944  1.00 26.62  ? 442  ILE C C   1 
ATOM   10551 O O   . ILE C 1 449 ? 17.794  19.530  -88.184  1.00 28.17  ? 442  ILE C O   1 
ATOM   10552 C CB  . ILE C 1 449 ? 18.081  16.329  -89.058  1.00 26.03  ? 442  ILE C CB  1 
ATOM   10553 C CG1 . ILE C 1 449 ? 17.960  14.959  -88.373  1.00 26.06  ? 442  ILE C CG1 1 
ATOM   10554 C CG2 . ILE C 1 449 ? 19.483  16.919  -88.965  1.00 27.27  ? 442  ILE C CG2 1 
ATOM   10555 C CD1 . ILE C 1 449 ? 18.851  13.855  -88.938  1.00 27.08  ? 442  ILE C CD1 1 
ATOM   10556 N N   . LYS C 1 450 ? 16.736  19.094  -90.130  1.00 27.94  ? 443  LYS C N   1 
ATOM   10557 C CA  . LYS C 1 450 ? 16.903  20.466  -90.684  1.00 30.74  ? 443  LYS C CA  1 
ATOM   10558 C C   . LYS C 1 450 ? 16.067  21.440  -89.849  1.00 30.39  ? 443  LYS C C   1 
ATOM   10559 O O   . LYS C 1 450 ? 16.572  22.544  -89.557  1.00 34.01  ? 443  LYS C O   1 
ATOM   10560 C CB  . LYS C 1 450 ? 16.524  20.511  -92.163  1.00 32.43  ? 443  LYS C CB  1 
ATOM   10561 C CG  . LYS C 1 450 ? 17.538  19.842  -93.089  1.00 33.06  ? 443  LYS C CG  1 
ATOM   10562 C CD  . LYS C 1 450 ? 17.019  19.667  -94.504  1.00 34.09  ? 443  LYS C CD  1 
ATOM   10563 C CE  . LYS C 1 450 ? 18.108  19.410  -95.513  1.00 33.39  ? 443  LYS C CE  1 
ATOM   10564 N NZ  . LYS C 1 450 ? 17.529  19.001  -96.816  1.00 34.80  ? 443  LYS C NZ  1 
ATOM   10565 N N   . ALA C 1 451 ? 14.848  21.037  -89.479  1.00 28.26  ? 444  ALA C N   1 
ATOM   10566 C CA  . ALA C 1 451 ? 13.950  21.810  -88.585  1.00 29.34  ? 444  ALA C CA  1 
ATOM   10567 C C   . ALA C 1 451 ? 14.647  22.044  -87.236  1.00 30.58  ? 444  ALA C C   1 
ATOM   10568 O O   . ALA C 1 451 ? 14.619  23.184  -86.737  1.00 29.82  ? 444  ALA C O   1 
ATOM   10569 C CB  . ALA C 1 451 ? 12.643  21.092  -88.397  1.00 28.37  ? 444  ALA C CB  1 
ATOM   10570 N N   . ALA C 1 452 ? 15.256  21.003  -86.669  1.00 29.79  ? 445  ALA C N   1 
ATOM   10571 C CA  . ALA C 1 452 ? 15.976  21.090  -85.384  1.00 33.51  ? 445  ALA C CA  1 
ATOM   10572 C C   . ALA C 1 452 ? 17.094  22.128  -85.525  1.00 36.62  ? 445  ALA C C   1 
ATOM   10573 O O   . ALA C 1 452 ? 17.209  22.994  -84.649  1.00 37.82  ? 445  ALA C O   1 
ATOM   10574 C CB  . ALA C 1 452 ? 16.526  19.744  -84.982  1.00 34.00  ? 445  ALA C CB  1 
ATOM   10575 N N   . ARG C 1 453 ? 17.866  22.052  -86.609  1.00 38.75  ? 446  ARG C N   1 
ATOM   10576 C CA  . ARG C 1 453 ? 18.999  22.976  -86.871  1.00 39.44  ? 446  ARG C CA  1 
ATOM   10577 C C   . ARG C 1 453 ? 18.458  24.412  -86.915  1.00 37.02  ? 446  ARG C C   1 
ATOM   10578 O O   . ARG C 1 453 ? 18.985  25.274  -86.204  1.00 35.44  ? 446  ARG C O   1 
ATOM   10579 C CB  . ARG C 1 453 ? 19.709  22.627  -88.182  1.00 42.08  ? 446  ARG C CB  1 
ATOM   10580 C CG  . ARG C 1 453 ? 20.952  23.476  -88.434  1.00 42.57  ? 446  ARG C CG  1 
ATOM   10581 C CD  . ARG C 1 453 ? 21.747  23.079  -89.663  1.00 42.74  ? 446  ARG C CD  1 
ATOM   10582 N NE  . ARG C 1 453 ? 22.485  21.835  -89.479  1.00 43.24  ? 446  ARG C NE  1 
ATOM   10583 C CZ  . ARG C 1 453 ? 23.581  21.693  -88.724  1.00 47.47  ? 446  ARG C CZ  1 
ATOM   10584 N NH1 . ARG C 1 453 ? 24.065  22.720  -88.033  1.00 47.83  ? 446  ARG C NH1 1 
ATOM   10585 N NH2 . ARG C 1 453 ? 24.177  20.508  -88.649  1.00 45.21  ? 446  ARG C NH2 1 
ATOM   10586 N N   . LYS C 1 454 ? 17.430  24.652  -87.726  1.00 38.22  ? 447  LYS C N   1 
ATOM   10587 C CA  . LYS C 1 454 ? 16.825  25.997  -87.896  1.00 43.04  ? 447  LYS C CA  1 
ATOM   10588 C C   . LYS C 1 454 ? 16.373  26.502  -86.516  1.00 42.85  ? 447  LYS C C   1 
ATOM   10589 O O   . LYS C 1 454 ? 16.607  27.693  -86.202  1.00 48.78  ? 447  LYS C O   1 
ATOM   10590 C CB  . LYS C 1 454 ? 15.705  25.903  -88.937  1.00 48.98  ? 447  LYS C CB  1 
ATOM   10591 C CG  . LYS C 1 454 ? 15.199  27.195  -89.566  1.00 55.29  ? 447  LYS C CG  1 
ATOM   10592 C CD  . LYS C 1 454 ? 14.525  26.988  -90.930  1.00 60.44  ? 447  LYS C CD  1 
ATOM   10593 C CE  . LYS C 1 454 ? 15.361  26.161  -91.893  1.00 63.78  ? 447  LYS C CE  1 
ATOM   10594 N NZ  . LYS C 1 454 ? 15.051  26.466  -93.310  1.00 69.83  ? 447  LYS C NZ  1 
ATOM   10595 N N   . ALA C 1 455 ? 15.794  25.623  -85.700  1.00 39.22  ? 448  ALA C N   1 
ATOM   10596 C CA  . ALA C 1 455 ? 15.264  25.960  -84.363  1.00 38.60  ? 448  ALA C CA  1 
ATOM   10597 C C   . ALA C 1 455 ? 16.399  26.425  -83.439  1.00 38.18  ? 448  ALA C C   1 
ATOM   10598 O O   . ALA C 1 455 ? 16.256  27.485  -82.815  1.00 34.12  ? 448  ALA C O   1 
ATOM   10599 C CB  . ALA C 1 455 ? 14.541  24.768  -83.800  1.00 39.85  ? 448  ALA C CB  1 
ATOM   10600 N N   . LEU C 1 456 ? 17.491  25.663  -83.369  1.00 39.21  ? 449  LEU C N   1 
ATOM   10601 C CA  . LEU C 1 456 ? 18.669  25.940  -82.500  1.00 40.13  ? 449  LEU C CA  1 
ATOM   10602 C C   . LEU C 1 456 ? 19.321  27.261  -82.910  1.00 40.49  ? 449  LEU C C   1 
ATOM   10603 O O   . LEU C 1 456 ? 19.661  28.033  -82.020  1.00 41.33  ? 449  LEU C O   1 
ATOM   10604 C CB  . LEU C 1 456 ? 19.667  24.776  -82.581  1.00 40.72  ? 449  LEU C CB  1 
ATOM   10605 C CG  . LEU C 1 456 ? 19.187  23.471  -81.947  1.00 43.30  ? 449  LEU C CG  1 
ATOM   10606 C CD1 . LEU C 1 456 ? 20.100  22.305  -82.284  1.00 41.94  ? 449  LEU C CD1 1 
ATOM   10607 C CD2 . LEU C 1 456 ? 19.046  23.607  -80.438  1.00 45.86  ? 449  LEU C CD2 1 
ATOM   10608 N N   . ALA C 1 457 ? 19.482  27.511  -84.205  1.00 44.47  ? 450  ALA C N   1 
ATOM   10609 C CA  . ALA C 1 457 ? 20.074  28.756  -84.740  1.00 46.17  ? 450  ALA C CA  1 
ATOM   10610 C C   . ALA C 1 457 ? 19.225  29.965  -84.308  1.00 46.24  ? 450  ALA C C   1 
ATOM   10611 O O   . ALA C 1 457 ? 19.819  30.983  -83.864  1.00 48.27  ? 450  ALA C O   1 
ATOM   10612 C CB  . ALA C 1 457 ? 20.200  28.664  -86.236  1.00 46.29  ? 450  ALA C CB  1 
ATOM   10613 N N   . ALA C 1 458 ? 17.897  29.866  -84.407  1.00 48.20  ? 451  ALA C N   1 
ATOM   10614 C CA  . ALA C 1 458 ? 16.945  30.931  -84.007  1.00 54.26  ? 451  ALA C CA  1 
ATOM   10615 C C   . ALA C 1 458 ? 17.031  31.159  -82.491  1.00 55.90  ? 451  ALA C C   1 
ATOM   10616 O O   . ALA C 1 458 ? 17.041  32.330  -82.051  1.00 56.96  ? 451  ALA C O   1 
ATOM   10617 C CB  . ALA C 1 458 ? 15.537  30.572  -84.427  1.00 57.06  ? 451  ALA C CB  1 
ATOM   10618 N N   . MET C 1 459 ? 17.095  30.071  -81.723  1.00 55.46  ? 452  MET C N   1 
ATOM   10619 C CA  . MET C 1 459 ? 17.236  30.090  -80.244  1.00 54.68  ? 452  MET C CA  1 
ATOM   10620 C C   . MET C 1 459 ? 18.539  30.786  -79.844  1.00 59.14  ? 452  MET C C   1 
ATOM   10621 O O   . MET C 1 459 ? 18.496  31.547  -78.881  1.00 68.60  ? 452  MET C O   1 
ATOM   10622 C CB  . MET C 1 459 ? 17.235  28.666  -79.684  1.00 50.50  ? 452  MET C CB  1 
ATOM   10623 C CG  . MET C 1 459 ? 15.859  28.052  -79.650  1.00 49.74  ? 452  MET C CG  1 
ATOM   10624 S SD  . MET C 1 459 ? 15.979  26.269  -79.543  1.00 49.79  ? 452  MET C SD  1 
ATOM   10625 C CE  . MET C 1 459 ? 16.742  26.042  -77.943  1.00 52.15  ? 452  MET C CE  1 
ATOM   10626 N N   . ARG C 1 460 ? 19.646  30.523  -80.545  1.00 55.52  ? 453  ARG C N   1 
ATOM   10627 C CA  . ARG C 1 460 ? 20.977  31.114  -80.236  1.00 53.55  ? 453  ARG C CA  1 
ATOM   10628 C C   . ARG C 1 460 ? 20.856  32.635  -80.366  1.00 58.25  ? 453  ARG C C   1 
ATOM   10629 O O   . ARG C 1 460 ? 21.298  33.334  -79.420  1.00 67.54  ? 453  ARG C O   1 
ATOM   10630 C CB  . ARG C 1 460 ? 22.062  30.532  -81.142  1.00 51.79  ? 453  ARG C CB  1 
ATOM   10631 C CG  . ARG C 1 460 ? 23.439  31.134  -80.930  1.00 51.64  ? 453  ARG C CG  1 
ATOM   10632 C CD  . ARG C 1 460 ? 24.543  30.438  -81.702  1.00 50.29  ? 453  ARG C CD  1 
ATOM   10633 N NE  . ARG C 1 460 ? 25.004  29.233  -81.022  1.00 48.01  ? 453  ARG C NE  1 
ATOM   10634 C CZ  . ARG C 1 460 ? 25.787  28.294  -81.564  1.00 45.08  ? 453  ARG C CZ  1 
ATOM   10635 N NH1 . ARG C 1 460 ? 26.198  28.402  -82.813  1.00 42.44  ? 453  ARG C NH1 1 
ATOM   10636 N NH2 . ARG C 1 460 ? 26.142  27.232  -80.862  1.00 46.00  ? 453  ARG C NH2 1 
ATOM   10637 N N   . VAL C 1 461 ? 20.233  33.109  -81.454  1.00 61.82  ? 454  VAL C N   1 
ATOM   10638 C CA  . VAL C 1 461 ? 19.994  34.558  -81.722  1.00 67.18  ? 454  VAL C CA  1 
ATOM   10639 C C   . VAL C 1 461 ? 19.215  35.158  -80.537  1.00 70.94  ? 454  VAL C C   1 
ATOM   10640 O O   . VAL C 1 461 ? 19.715  36.143  -79.931  1.00 82.62  ? 454  VAL C O   1 
ATOM   10641 C CB  . VAL C 1 461 ? 19.276  34.784  -83.067  1.00 73.01  ? 454  VAL C CB  1 
ATOM   10642 C CG1 . VAL C 1 461 ? 18.791  36.220  -83.213  1.00 77.02  ? 454  VAL C CG1 1 
ATOM   10643 C CG2 . VAL C 1 461 ? 20.146  34.400  -84.255  1.00 71.22  ? 454  VAL C CG2 1 
ATOM   10644 N N   . SER C 1 462 ? 18.066  34.560  -80.189  1.00 73.82  ? 455  SER C N   1 
ATOM   10645 C CA  . SER C 1 462 ? 17.208  34.970  -79.040  1.00 77.81  ? 455  SER C CA  1 
ATOM   10646 C C   . SER C 1 462 ? 18.087  35.193  -77.808  1.00 81.54  ? 455  SER C C   1 
ATOM   10647 O O   . SER C 1 462 ? 18.051  36.300  -77.251  1.00 89.96  ? 455  SER C O   1 
ATOM   10648 C CB  . SER C 1 462 ? 16.130  33.956  -78.734  1.00 78.40  ? 455  SER C CB  1 
ATOM   10649 O OG  . SER C 1 462 ? 15.445  33.571  -79.911  1.00 85.94  ? 455  SER C OG  1 
ATOM   10650 N N   . VAL C 1 463 ? 18.852  34.164  -77.425  1.00 84.08  ? 456  VAL C N   1 
ATOM   10651 C CA  . VAL C 1 463 ? 19.760  34.178  -76.241  1.00 89.82  ? 456  VAL C CA  1 
ATOM   10652 C C   . VAL C 1 463 ? 20.726  35.355  -76.392  1.00 100.15 ? 456  VAL C C   1 
ATOM   10653 O O   . VAL C 1 463 ? 20.598  36.280  -75.554  1.00 118.66 ? 456  VAL C O   1 
ATOM   10654 C CB  . VAL C 1 463 ? 20.466  32.817  -76.071  1.00 80.11  ? 456  VAL C CB  1 
ATOM   10655 C CG1 . VAL C 1 463 ? 21.664  32.870  -75.140  1.00 75.12  ? 456  VAL C CG1 1 
ATOM   10656 C CG2 . VAL C 1 463 ? 19.468  31.764  -75.603  1.00 75.39  ? 456  VAL C CG2 1 
ATOM   10657 N N   . GLU C 1 464 ? 21.595  35.343  -77.418  1.00 97.49  ? 457  GLU C N   1 
ATOM   10658 C CA  . GLU C 1 464 ? 22.606  36.405  -77.679  1.00 93.04  ? 457  GLU C CA  1 
ATOM   10659 C C   . GLU C 1 464 ? 21.962  37.795  -77.558  1.00 91.49  ? 457  GLU C C   1 
ATOM   10660 O O   . GLU C 1 464 ? 22.552  38.648  -76.814  1.00 103.86 ? 457  GLU C O   1 
ATOM   10661 C CB  . GLU C 1 464 ? 23.256  36.218  -79.050  1.00 99.42  ? 457  GLU C CB  1 
ATOM   10662 C CG  . GLU C 1 464 ? 24.155  34.998  -79.134  1.00 110.00 ? 457  GLU C CG  1 
ATOM   10663 C CD  . GLU C 1 464 ? 24.523  34.552  -80.544  1.00 116.87 ? 457  GLU C CD  1 
ATOM   10664 O OE1 . GLU C 1 464 ? 23.758  34.860  -81.498  1.00 115.16 ? 457  GLU C OE1 1 
ATOM   10665 O OE2 . GLU C 1 464 ? 25.581  33.906  -80.684  1.00 114.88 ? 457  GLU C OE2 1 
ATOM   10666 N N   . GLU C 1 465 ? 20.800  38.007  -78.199  1.00 90.74  ? 458  GLU C N   1 
ATOM   10667 C CA  . GLU C 1 465 ? 20.042  39.297  -78.151  1.00 94.48  ? 458  GLU C CA  1 
ATOM   10668 C C   . GLU C 1 465 ? 19.749  39.705  -76.691  1.00 100.59 ? 458  GLU C C   1 
ATOM   10669 O O   . GLU C 1 465 ? 20.323  40.733  -76.222  1.00 114.31 ? 458  GLU C O   1 
ATOM   10670 C CB  . GLU C 1 465 ? 18.724  39.206  -78.928  1.00 96.07  ? 458  GLU C CB  1 
ATOM   10671 C CG  . GLU C 1 465 ? 18.884  39.177  -80.443  1.00 93.69  ? 458  GLU C CG  1 
ATOM   10672 C CD  . GLU C 1 465 ? 17.567  39.047  -81.189  1.00 94.05  ? 458  GLU C CD  1 
ATOM   10673 O OE1 . GLU C 1 465 ? 16.606  38.484  -80.611  1.00 84.39  ? 458  GLU C OE1 1 
ATOM   10674 O OE2 . GLU C 1 465 ? 17.507  39.496  -82.355  1.00 90.92  ? 458  GLU C OE2 1 
ATOM   10675 N N   . ALA C 1 466 ? 18.872  38.946  -76.012  1.00 101.53 ? 459  ALA C N   1 
ATOM   10676 C CA  . ALA C 1 466 ? 18.529  39.062  -74.571  1.00 103.32 ? 459  ALA C CA  1 
ATOM   10677 C C   . ALA C 1 466 ? 19.768  39.471  -73.772  1.00 109.17 ? 459  ALA C C   1 
ATOM   10678 O O   . ALA C 1 466 ? 19.721  40.542  -73.112  1.00 114.14 ? 459  ALA C O   1 
ATOM   10679 C CB  . ALA C 1 466 ? 17.973  37.753  -74.050  1.00 94.74  ? 459  ALA C CB  1 
ATOM   10680 N N   . LEU C 1 467 ? 20.835  38.656  -73.854  1.00 115.26 ? 460  LEU C N   1 
ATOM   10681 C CA  . LEU C 1 467 ? 22.077  38.786  -73.042  1.00 116.78 ? 460  LEU C CA  1 
ATOM   10682 C C   . LEU C 1 467 ? 22.693  40.183  -73.199  1.00 115.36 ? 460  LEU C C   1 
ATOM   10683 O O   . LEU C 1 467 ? 23.013  40.790  -72.142  1.00 119.79 ? 460  LEU C O   1 
ATOM   10684 C CB  . LEU C 1 467 ? 23.079  37.691  -73.424  1.00 112.81 ? 460  LEU C CB  1 
ATOM   10685 C CG  . LEU C 1 467 ? 22.647  36.234  -73.191  1.00 110.48 ? 460  LEU C CG  1 
ATOM   10686 C CD1 . LEU C 1 467 ? 23.839  35.396  -72.731  1.00 105.23 ? 460  LEU C CD1 1 
ATOM   10687 C CD2 . LEU C 1 467 ? 21.491  36.074  -72.198  1.00 102.28 ? 460  LEU C CD2 1 
ATOM   10688 N N   . GLU C 1 468 ? 22.816  40.698  -74.431  1.00 113.28 ? 461  GLU C N   1 
ATOM   10689 C CA  . GLU C 1 468 ? 23.199  42.115  -74.693  1.00 114.73 ? 461  GLU C CA  1 
ATOM   10690 C C   . GLU C 1 468 ? 22.219  43.039  -73.953  1.00 128.18 ? 461  GLU C C   1 
ATOM   10691 O O   . GLU C 1 468 ? 22.671  43.816  -73.078  1.00 148.53 ? 461  GLU C O   1 
ATOM   10692 C CB  . GLU C 1 468 ? 23.231  42.402  -76.192  1.00 110.23 ? 461  GLU C CB  1 
ATOM   10693 C CG  . GLU C 1 468 ? 24.356  41.662  -76.898  1.00 109.73 ? 461  GLU C CG  1 
ATOM   10694 C CD  . GLU C 1 468 ? 24.260  41.634  -78.414  1.00 109.47 ? 461  GLU C CD  1 
ATOM   10695 O OE1 . GLU C 1 468 ? 23.739  42.612  -78.983  1.00 109.80 ? 461  GLU C OE1 1 
ATOM   10696 O OE2 . GLU C 1 468 ? 24.691  40.625  -79.018  1.00 100.04 ? 461  GLU C OE2 1 
ATOM   10697 N N   . VAL C 1 469 ? 20.921  42.904  -74.241  1.00 130.99 ? 462  VAL C N   1 
ATOM   10698 C CA  . VAL C 1 469 ? 19.832  43.768  -73.678  1.00 123.98 ? 462  VAL C CA  1 
ATOM   10699 C C   . VAL C 1 469 ? 19.780  43.635  -72.138  1.00 128.12 ? 462  VAL C C   1 
ATOM   10700 O O   . VAL C 1 469 ? 18.903  44.286  -71.551  1.00 123.99 ? 462  VAL C O   1 
ATOM   10701 C CB  . VAL C 1 469 ? 18.452  43.477  -74.327  1.00 111.44 ? 462  VAL C CB  1 
ATOM   10702 C CG1 . VAL C 1 469 ? 17.424  44.560  -74.018  1.00 101.88 ? 462  VAL C CG1 1 
ATOM   10703 C CG2 . VAL C 1 469 ? 18.530  43.267  -75.836  1.00 108.69 ? 462  VAL C CG2 1 
ATOM   10704 N N   . SER C 1 470 ? 20.643  42.834  -71.485  1.00 132.38 ? 463  SER C N   1 
ATOM   10705 C CA  . SER C 1 470 ? 20.708  42.658  -70.002  1.00 124.97 ? 463  SER C CA  1 
ATOM   10706 C C   . SER C 1 470 ? 21.991  43.279  -69.421  1.00 133.90 ? 463  SER C C   1 
ATOM   10707 O O   . SER C 1 470 ? 21.861  44.190  -68.556  1.00 139.65 ? 463  SER C O   1 
ATOM   10708 C CB  . SER C 1 470 ? 20.583  41.199  -69.604  1.00 114.94 ? 463  SER C CB  1 
ATOM   10709 O OG  . SER C 1 470 ? 21.851  40.593  -69.398  1.00 110.37 ? 463  SER C OG  1 
ATOM   10710 N N   . ALA C 1 471 ? 23.166  42.823  -69.891  1.00 131.78 ? 464  ALA C N   1 
ATOM   10711 C CA  . ALA C 1 471 ? 24.521  43.233  -69.430  1.00 122.97 ? 464  ALA C CA  1 
ATOM   10712 C C   . ALA C 1 471 ? 24.600  44.760  -69.293  1.00 127.26 ? 464  ALA C C   1 
ATOM   10713 O O   . ALA C 1 471 ? 25.303  45.226  -68.397  1.00 126.79 ? 464  ALA C O   1 
ATOM   10714 C CB  . ALA C 1 471 ? 25.582  42.715  -70.374  1.00 112.72 ? 464  ALA C CB  1 
ATOM   10715 N N   . LYS C 1 472 ? 23.840  45.485  -70.126  1.00 129.46 ? 465  LYS C N   1 
ATOM   10716 C CA  . LYS C 1 472 ? 23.662  46.967  -70.117  1.00 127.51 ? 465  LYS C CA  1 
ATOM   10717 C C   . LYS C 1 472 ? 23.499  47.485  -68.675  1.00 134.37 ? 465  LYS C C   1 
ATOM   10718 O O   . LYS C 1 472 ? 24.211  48.444  -68.313  1.00 142.10 ? 465  LYS C O   1 
ATOM   10719 C CB  . LYS C 1 472 ? 22.451  47.374  -70.972  1.00 118.08 ? 465  LYS C CB  1 
ATOM   10720 C CG  . LYS C 1 472 ? 22.552  47.134  -72.476  1.00 114.50 ? 465  LYS C CG  1 
ATOM   10721 C CD  . LYS C 1 472 ? 23.752  47.771  -73.167  1.00 111.60 ? 465  LYS C CD  1 
ATOM   10722 C CE  . LYS C 1 472 ? 23.743  47.598  -74.675  1.00 109.43 ? 465  LYS C CE  1 
ATOM   10723 N NZ  . LYS C 1 472 ? 23.945  46.187  -75.097  1.00 107.90 ? 465  LYS C NZ  1 
ATOM   10724 N N   . GLU C 1 473 ? 22.632  46.853  -67.875  1.00 130.05 ? 466  GLU C N   1 
ATOM   10725 C CA  . GLU C 1 473 ? 22.433  47.207  -66.446  1.00 124.92 ? 466  GLU C CA  1 
ATOM   10726 C C   . GLU C 1 473 ? 23.792  47.163  -65.733  1.00 124.81 ? 466  GLU C C   1 
ATOM   10727 O O   . GLU C 1 473 ? 24.541  46.185  -65.967  1.00 120.11 ? 466  GLU C O   1 
ATOM   10728 C CB  . GLU C 1 473 ? 21.426  46.270  -65.786  1.00 119.54 ? 466  GLU C CB  1 
ATOM   10729 C CG  . GLU C 1 473 ? 20.880  46.842  -64.493  1.00 115.97 ? 466  GLU C CG  1 
ATOM   10730 C CD  . GLU C 1 473 ? 19.996  45.913  -63.670  1.00 113.40 ? 466  GLU C CD  1 
ATOM   10731 O OE1 . GLU C 1 473 ? 20.393  44.753  -63.473  1.00 115.49 ? 466  GLU C OE1 1 
ATOM   10732 O OE2 . GLU C 1 473 ? 18.910  46.349  -63.211  1.00 105.57 ? 466  GLU C OE2 1 
ATOM   10733 N N   . GLN C 1 474 ? 24.079  48.162  -64.882  1.00 121.34 ? 467  GLN C N   1 
ATOM   10734 C CA  . GLN C 1 474 ? 25.333  48.285  -64.077  1.00 118.55 ? 467  GLN C CA  1 
ATOM   10735 C C   . GLN C 1 474 ? 25.188  49.388  -63.017  1.00 119.24 ? 467  GLN C C   1 
ATOM   10736 O O   . GLN C 1 474 ? 24.064  49.882  -62.863  1.00 112.77 ? 467  GLN C O   1 
ATOM   10737 C CB  . GLN C 1 474 ? 26.514  48.580  -64.991  1.00 112.95 ? 467  GLN C CB  1 
ATOM   10738 C CG  . GLN C 1 474 ? 26.921  47.373  -65.820  1.00 110.71 ? 467  GLN C CG  1 
ATOM   10739 C CD  . GLN C 1 474 ? 28.096  47.675  -66.705  1.00 116.99 ? 467  GLN C CD  1 
ATOM   10740 O OE1 . GLN C 1 474 ? 28.235  48.785  -67.208  1.00 119.82 ? 467  GLN C OE1 1 
ATOM   10741 N NE2 . GLN C 1 474 ? 28.938  46.677  -66.928  1.00 123.31 ? 467  GLN C NE2 1 
ATOM   10742 N N   . GLN C 1 475 ? 26.293  49.759  -62.344  1.00 116.69 ? 468  GLN C N   1 
ATOM   10743 C CA  . GLN C 1 475 ? 26.315  50.609  -61.119  1.00 112.47 ? 468  GLN C CA  1 
ATOM   10744 C C   . GLN C 1 475 ? 25.033  50.325  -60.326  1.00 110.13 ? 468  GLN C C   1 
ATOM   10745 O O   . GLN C 1 475 ? 24.746  49.160  -60.089  1.00 103.52 ? 468  GLN C O   1 
ATOM   10746 C CB  . GLN C 1 475 ? 26.470  52.093  -61.469  1.00 109.20 ? 468  GLN C CB  1 
ATOM   10747 C CG  . GLN C 1 475 ? 26.284  53.039  -60.284  1.00 113.83 ? 468  GLN C CG  1 
ATOM   10748 C CD  . GLN C 1 475 ? 27.297  52.843  -59.176  1.00 116.96 ? 468  GLN C CD  1 
ATOM   10749 O OE1 . GLN C 1 475 ? 28.504  52.885  -59.398  1.00 117.10 ? 468  GLN C OE1 1 
ATOM   10750 N NE2 . GLN C 1 475 ? 26.811  52.636  -57.960  1.00 108.75 ? 468  GLN C NE2 1 
ATOM   10751 N N   . ALA D 1 15  ? 2.463   -21.894 -84.414  1.00 97.92  ? 8    ALA D N   1 
ATOM   10752 C CA  . ALA D 1 15  ? 2.788   -21.062 -85.613  1.00 88.92  ? 8    ALA D CA  1 
ATOM   10753 C C   . ALA D 1 15  ? 3.581   -19.816 -85.182  1.00 72.97  ? 8    ALA D C   1 
ATOM   10754 O O   . ALA D 1 15  ? 3.735   -19.569 -83.966  1.00 61.62  ? 8    ALA D O   1 
ATOM   10755 C CB  . ALA D 1 15  ? 1.507   -20.708 -86.341  1.00 87.23  ? 8    ALA D CB  1 
ATOM   10756 N N   . SER D 1 16  ? 4.083   -19.054 -86.154  1.00 61.40  ? 9    SER D N   1 
ATOM   10757 C CA  . SER D 1 16  ? 4.615   -17.689 -85.927  1.00 49.67  ? 9    SER D CA  1 
ATOM   10758 C C   . SER D 1 16  ? 3.451   -16.778 -85.497  1.00 41.02  ? 9    SER D C   1 
ATOM   10759 O O   . SER D 1 16  ? 2.272   -17.107 -85.754  1.00 33.55  ? 9    SER D O   1 
ATOM   10760 C CB  . SER D 1 16  ? 5.350   -17.175 -87.148  1.00 47.62  ? 9    SER D CB  1 
ATOM   10761 O OG  . SER D 1 16  ? 4.448   -16.774 -88.169  1.00 45.43  ? 9    SER D OG  1 
ATOM   10762 N N   . ALA D 1 17  ? 3.774   -15.673 -84.837  1.00 35.97  ? 10   ALA D N   1 
ATOM   10763 C CA  . ALA D 1 17  ? 2.832   -14.581 -84.527  1.00 34.08  ? 10   ALA D CA  1 
ATOM   10764 C C   . ALA D 1 17  ? 2.235   -14.033 -85.827  1.00 30.78  ? 10   ALA D C   1 
ATOM   10765 O O   . ALA D 1 17  ? 1.029   -13.760 -85.863  1.00 30.36  ? 10   ALA D O   1 
ATOM   10766 C CB  . ALA D 1 17  ? 3.551   -13.510 -83.752  1.00 34.28  ? 10   ALA D CB  1 
ATOM   10767 N N   . LEU D 1 18  ? 3.056   -13.858 -86.857  1.00 28.72  ? 11   LEU D N   1 
ATOM   10768 C CA  . LEU D 1 18  ? 2.603   -13.283 -88.147  1.00 29.01  ? 11   LEU D CA  1 
ATOM   10769 C C   . LEU D 1 18  ? 1.458   -14.128 -88.705  1.00 27.52  ? 11   LEU D C   1 
ATOM   10770 O O   . LEU D 1 18  ? 0.445   -13.556 -89.135  1.00 24.67  ? 11   LEU D O   1 
ATOM   10771 C CB  . LEU D 1 18  ? 3.774   -13.245 -89.133  1.00 30.54  ? 11   LEU D CB  1 
ATOM   10772 C CG  . LEU D 1 18  ? 3.443   -12.582 -90.471  1.00 31.36  ? 11   LEU D CG  1 
ATOM   10773 C CD1 . LEU D 1 18  ? 2.729   -11.252 -90.253  1.00 31.90  ? 11   LEU D CD1 1 
ATOM   10774 C CD2 . LEU D 1 18  ? 4.684   -12.385 -91.322  1.00 29.59  ? 11   LEU D CD2 1 
ATOM   10775 N N   . ALA D 1 19  ? 1.639   -15.449 -88.677  1.00 28.32  ? 12   ALA D N   1 
ATOM   10776 C CA  . ALA D 1 19  ? 0.686   -16.477 -89.163  1.00 28.82  ? 12   ALA D CA  1 
ATOM   10777 C C   . ALA D 1 19  ? -0.644  -16.385 -88.413  1.00 26.90  ? 12   ALA D C   1 
ATOM   10778 O O   . ALA D 1 19  ? -1.689  -16.439 -89.078  1.00 26.17  ? 12   ALA D O   1 
ATOM   10779 C CB  . ALA D 1 19  ? 1.300   -17.851 -89.008  1.00 30.82  ? 12   ALA D CB  1 
ATOM   10780 N N   . CYS D 1 20  ? -0.599  -16.266 -87.086  1.00 27.55  ? 13   CYS D N   1 
ATOM   10781 C CA  . CYS D 1 20  ? -1.799  -16.156 -86.221  1.00 29.79  ? 13   CYS D CA  1 
ATOM   10782 C C   . CYS D 1 20  ? -2.457  -14.788 -86.435  1.00 25.19  ? 13   CYS D C   1 
ATOM   10783 O O   . CYS D 1 20  ? -3.692  -14.767 -86.523  1.00 22.62  ? 13   CYS D O   1 
ATOM   10784 C CB  . CYS D 1 20  ? -1.463  -16.394 -84.753  1.00 35.72  ? 13   CYS D CB  1 
ATOM   10785 S SG  . CYS D 1 20  ? -0.846  -18.069 -84.423  1.00 51.12  ? 13   CYS D SG  1 
ATOM   10786 N N   . SER D 1 21  ? -1.686  -13.699 -86.548  1.00 22.30  ? 14   SER D N   1 
ATOM   10787 C CA  . SER D 1 21  ? -2.249  -12.336 -86.768  1.00 21.84  ? 14   SER D CA  1 
ATOM   10788 C C   . SER D 1 21  ? -2.964  -12.284 -88.129  1.00 23.78  ? 14   SER D C   1 
ATOM   10789 O O   . SER D 1 21  ? -3.999  -11.600 -88.245  1.00 23.74  ? 14   SER D O   1 
ATOM   10790 C CB  . SER D 1 21  ? -1.207  -11.252 -86.620  1.00 20.82  ? 14   SER D CB  1 
ATOM   10791 O OG  . SER D 1 21  ? -0.338  -11.196 -87.719  1.00 17.98  ? 14   SER D OG  1 
ATOM   10792 N N   . ALA D 1 22  ? -2.457  -13.037 -89.108  1.00 24.01  ? 15   ALA D N   1 
ATOM   10793 C CA  . ALA D 1 22  ? -3.028  -13.174 -90.459  1.00 24.93  ? 15   ALA D CA  1 
ATOM   10794 C C   . ALA D 1 22  ? -4.341  -13.965 -90.394  1.00 26.14  ? 15   ALA D C   1 
ATOM   10795 O O   . ALA D 1 22  ? -5.365  -13.465 -90.892  1.00 27.65  ? 15   ALA D O   1 
ATOM   10796 C CB  . ALA D 1 22  ? -2.015  -13.837 -91.366  1.00 25.64  ? 15   ALA D CB  1 
ATOM   10797 N N   . HIS D 1 23  ? -4.308  -15.160 -89.809  1.00 26.83  ? 16   HIS D N   1 
ATOM   10798 C CA  . HIS D 1 23  ? -5.475  -16.071 -89.681  1.00 27.13  ? 16   HIS D CA  1 
ATOM   10799 C C   . HIS D 1 23  ? -6.639  -15.316 -89.018  1.00 25.79  ? 16   HIS D C   1 
ATOM   10800 O O   . HIS D 1 23  ? -7.816  -15.551 -89.380  1.00 23.23  ? 16   HIS D O   1 
ATOM   10801 C CB  . HIS D 1 23  ? -5.050  -17.321 -88.899  1.00 29.67  ? 16   HIS D CB  1 
ATOM   10802 C CG  . HIS D 1 23  ? -6.199  -18.190 -88.545  1.00 31.83  ? 16   HIS D CG  1 
ATOM   10803 N ND1 . HIS D 1 23  ? -6.840  -18.923 -89.493  1.00 37.04  ? 16   HIS D ND1 1 
ATOM   10804 C CD2 . HIS D 1 23  ? -6.844  -18.411 -87.387  1.00 34.44  ? 16   HIS D CD2 1 
ATOM   10805 C CE1 . HIS D 1 23  ? -7.847  -19.567 -88.948  1.00 38.34  ? 16   HIS D CE1 1 
ATOM   10806 N NE2 . HIS D 1 23  ? -7.868  -19.272 -87.658  1.00 35.66  ? 16   HIS D NE2 1 
ATOM   10807 N N   . ALA D 1 24  ? -6.300  -14.424 -88.085  1.00 24.07  ? 17   ALA D N   1 
ATOM   10808 C CA  . ALA D 1 24  ? -7.262  -13.679 -87.252  1.00 23.10  ? 17   ALA D CA  1 
ATOM   10809 C C   . ALA D 1 24  ? -7.832  -12.512 -88.051  1.00 22.42  ? 17   ALA D C   1 
ATOM   10810 O O   . ALA D 1 24  ? -9.022  -12.263 -87.932  1.00 22.78  ? 17   ALA D O   1 
ATOM   10811 C CB  . ALA D 1 24  ? -6.607  -13.194 -85.986  1.00 22.90  ? 17   ALA D CB  1 
ATOM   10812 N N   . LEU D 1 25  ? -7.012  -11.790 -88.806  1.00 22.51  ? 18   LEU D N   1 
ATOM   10813 C CA  . LEU D 1 25  ? -7.546  -10.703 -89.669  1.00 24.23  ? 18   LEU D CA  1 
ATOM   10814 C C   . LEU D 1 25  ? -8.503  -11.277 -90.734  1.00 24.18  ? 18   LEU D C   1 
ATOM   10815 O O   . LEU D 1 25  ? -9.512  -10.609 -91.054  1.00 22.66  ? 18   LEU D O   1 
ATOM   10816 C CB  . LEU D 1 25  ? -6.384  -9.939  -90.296  1.00 23.94  ? 18   LEU D CB  1 
ATOM   10817 C CG  . LEU D 1 25  ? -5.557  -9.114  -89.307  1.00 22.47  ? 18   LEU D CG  1 
ATOM   10818 C CD1 . LEU D 1 25  ? -4.333  -8.554  -89.991  1.00 23.30  ? 18   LEU D CD1 1 
ATOM   10819 C CD2 . LEU D 1 25  ? -6.367  -7.979  -88.735  1.00 22.03  ? 18   LEU D CD2 1 
ATOM   10820 N N   A ASN D 1 26  ? -8.198  -12.479 -91.235  0.45 24.27  ? 19   ASN D N   1 
ATOM   10821 N N   B ASN D 1 26  ? -8.171  -12.442 -91.304  0.55 23.99  ? 19   ASN D N   1 
ATOM   10822 C CA  A ASN D 1 26  ? -9.064  -13.266 -92.155  0.45 24.78  ? 19   ASN D CA  1 
ATOM   10823 C CA  B ASN D 1 26  ? -9.035  -13.167 -92.274  0.55 24.30  ? 19   ASN D CA  1 
ATOM   10824 C C   A ASN D 1 26  ? -10.414 -13.505 -91.469  0.45 24.54  ? 19   ASN D C   1 
ATOM   10825 C C   B ASN D 1 26  ? -10.408 -13.364 -91.633  0.55 23.95  ? 19   ASN D C   1 
ATOM   10826 O O   A ASN D 1 26  ? -11.455 -13.299 -92.126  0.45 23.98  ? 19   ASN D O   1 
ATOM   10827 O O   B ASN D 1 26  ? -11.444 -13.133 -92.303  0.55 23.41  ? 19   ASN D O   1 
ATOM   10828 C CB  A ASN D 1 26  ? -8.428  -14.606 -92.546  0.45 25.28  ? 19   ASN D CB  1 
ATOM   10829 C CB  B ASN D 1 26  ? -8.489  -14.551 -92.644  0.55 24.91  ? 19   ASN D CB  1 
ATOM   10830 C CG  A ASN D 1 26  ? -9.315  -15.454 -93.438  0.45 25.89  ? 19   ASN D CG  1 
ATOM   10831 C CG  B ASN D 1 26  ? -7.614  -14.562 -93.879  0.55 25.49  ? 19   ASN D CG  1 
ATOM   10832 O OD1 A ASN D 1 26  ? -9.553  -15.103 -94.593  0.45 26.11  ? 19   ASN D OD1 1 
ATOM   10833 O OD1 B ASN D 1 26  ? -7.792  -13.746 -94.786  0.55 27.52  ? 19   ASN D OD1 1 
ATOM   10834 N ND2 A ASN D 1 26  ? -9.813  -16.568 -92.920  0.45 26.14  ? 19   ASN D ND2 1 
ATOM   10835 N ND2 B ASN D 1 26  ? -6.675  -15.496 -93.930  0.55 25.11  ? 19   ASN D ND2 1 
ATOM   10836 N N   A LEU D 1 27  ? -10.388 -13.912 -90.195  0.56 24.31  ? 20   LEU D N   1 
ATOM   10837 N N   B LEU D 1 27  ? -10.393 -13.805 -90.369  0.44 23.24  ? 20   LEU D N   1 
ATOM   10838 C CA  A LEU D 1 27  ? -11.616 -14.184 -89.402  0.56 25.97  ? 20   LEU D CA  1 
ATOM   10839 C CA  B LEU D 1 27  ? -11.608 -14.138 -89.572  0.44 24.22  ? 20   LEU D CA  1 
ATOM   10840 C C   A LEU D 1 27  ? -12.419 -12.896 -89.163  0.56 25.25  ? 20   LEU D C   1 
ATOM   10841 C C   B LEU D 1 27  ? -12.421 -12.874 -89.261  0.44 24.38  ? 20   LEU D C   1 
ATOM   10842 O O   A LEU D 1 27  ? -13.649 -12.965 -89.249  0.56 26.16  ? 20   LEU D O   1 
ATOM   10843 O O   B LEU D 1 27  ? -13.661 -12.948 -89.318  0.44 25.15  ? 20   LEU D O   1 
ATOM   10844 C CB  A LEU D 1 27  ? -11.203 -14.883 -88.113  0.56 26.31  ? 20   LEU D CB  1 
ATOM   10845 C CB  B LEU D 1 27  ? -11.204 -14.837 -88.273  0.44 23.38  ? 20   LEU D CB  1 
ATOM   10846 C CG  A LEU D 1 27  ? -11.081 -16.391 -88.312  0.56 27.50  ? 20   LEU D CG  1 
ATOM   10847 C CG  B LEU D 1 27  ? -12.287 -14.846 -87.197  0.44 23.30  ? 20   LEU D CG  1 
ATOM   10848 C CD1 A LEU D 1 27  ? -10.408 -17.060 -87.131  0.56 29.81  ? 20   LEU D CD1 1 
ATOM   10849 C CD1 B LEU D 1 27  ? -13.125 -16.113 -87.278  0.44 23.17  ? 20   LEU D CD1 1 
ATOM   10850 C CD2 A LEU D 1 27  ? -12.450 -17.004 -88.569  0.56 27.21  ? 20   LEU D CD2 1 
ATOM   10851 C CD2 B LEU D 1 27  ? -11.676 -14.697 -85.818  0.44 22.74  ? 20   LEU D CD2 1 
ATOM   10852 N N   . ILE D 1 28  ? -11.755 -11.763 -88.944  1.00 25.19  ? 21   ILE D N   1 
ATOM   10853 C CA  . ILE D 1 28  ? -12.419 -10.444 -88.711  1.00 25.31  ? 21   ILE D CA  1 
ATOM   10854 C C   . ILE D 1 28  ? -13.222 -10.021 -89.948  1.00 27.30  ? 21   ILE D C   1 
ATOM   10855 O O   . ILE D 1 28  ? -14.302 -9.418  -89.745  1.00 23.51  ? 21   ILE D O   1 
ATOM   10856 C CB  . ILE D 1 28  ? -11.381 -9.389  -88.289  1.00 25.45  ? 21   ILE D CB  1 
ATOM   10857 C CG1 . ILE D 1 28  ? -10.854 -9.705  -86.890  1.00 25.16  ? 21   ILE D CG1 1 
ATOM   10858 C CG2 . ILE D 1 28  ? -11.937 -7.977  -88.377  1.00 25.60  ? 21   ILE D CG2 1 
ATOM   10859 C CD1 . ILE D 1 28  ? -9.671  -8.880  -86.481  1.00 25.57  ? 21   ILE D CD1 1 
ATOM   10860 N N   . GLU D 1 29  ? -12.728 -10.321 -91.158  1.00 29.01  ? 22   GLU D N   1 
ATOM   10861 C CA  . GLU D 1 29  ? -13.406 -9.970  -92.442  1.00 31.37  ? 22   GLU D CA  1 
ATOM   10862 C C   . GLU D 1 29  ? -14.659 -10.824 -92.655  1.00 29.10  ? 22   GLU D C   1 
ATOM   10863 O O   . GLU D 1 29  ? -15.643 -10.264 -93.114  1.00 28.81  ? 22   GLU D O   1 
ATOM   10864 C CB  . GLU D 1 29  ? -12.506 -10.208 -93.656  1.00 32.52  ? 22   GLU D CB  1 
ATOM   10865 C CG  . GLU D 1 29  ? -11.237 -9.393  -93.642  1.00 36.49  ? 22   GLU D CG  1 
ATOM   10866 C CD  . GLU D 1 29  ? -10.359 -9.556  -94.874  1.00 38.02  ? 22   GLU D CD  1 
ATOM   10867 O OE1 . GLU D 1 29  ? -10.937 -9.604  -96.019  1.00 33.42  ? 22   GLU D OE1 1 
ATOM   10868 O OE2 . GLU D 1 29  ? -9.105  -9.606  -94.684  1.00 33.70  ? 22   GLU D OE2 1 
ATOM   10869 N N   . LYS D 1 30  ? -14.584 -12.128 -92.370  1.00 30.58  ? 23   LYS D N   1 
ATOM   10870 C CA  . LYS D 1 30  ? -15.674 -13.121 -92.554  1.00 33.37  ? 23   LYS D CA  1 
ATOM   10871 C C   . LYS D 1 30  ? -16.906 -12.634 -91.776  1.00 33.54  ? 23   LYS D C   1 
ATOM   10872 O O   . LYS D 1 30  ? -16.746 -12.132 -90.649  1.00 33.19  ? 23   LYS D O   1 
ATOM   10873 C CB  . LYS D 1 30  ? -15.217 -14.515 -92.098  1.00 37.73  ? 23   LYS D CB  1 
ATOM   10874 C CG  . LYS D 1 30  ? -14.201 -15.184 -93.023  1.00 43.18  ? 23   LYS D CG  1 
ATOM   10875 C CD  . LYS D 1 30  ? -13.638 -16.553 -92.589  1.00 44.70  ? 23   LYS D CD  1 
ATOM   10876 C CE  . LYS D 1 30  ? -14.632 -17.706 -92.633  1.00 48.77  ? 23   LYS D CE  1 
ATOM   10877 N NZ  . LYS D 1 30  ? -15.618 -17.608 -93.748  1.00 52.90  ? 23   LYS D NZ  1 
ATOM   10878 N N   . ARG D 1 31  ? -18.089 -12.702 -92.384  1.00 30.72  ? 24   ARG D N   1 
ATOM   10879 C CA  . ARG D 1 31  ? -19.388 -12.395 -91.737  1.00 29.37  ? 24   ARG D CA  1 
ATOM   10880 C C   . ARG D 1 31  ? -20.161 -13.683 -91.525  1.00 27.31  ? 24   ARG D C   1 
ATOM   10881 O O   . ARG D 1 31  ? -21.122 -13.643 -90.736  1.00 29.34  ? 24   ARG D O   1 
ATOM   10882 C CB  . ARG D 1 31  ? -20.269 -11.492 -92.596  1.00 31.56  ? 24   ARG D CB  1 
ATOM   10883 C CG  . ARG D 1 31  ? -19.721 -10.091 -92.779  1.00 34.46  ? 24   ARG D CG  1 
ATOM   10884 C CD  . ARG D 1 31  ? -19.700 -9.319  -91.488  1.00 38.67  ? 24   ARG D CD  1 
ATOM   10885 N NE  . ARG D 1 31  ? -19.256 -8.001  -91.895  1.00 43.20  ? 24   ARG D NE  1 
ATOM   10886 C CZ  . ARG D 1 31  ? -20.050 -7.029  -92.332  1.00 45.70  ? 24   ARG D CZ  1 
ATOM   10887 N NH1 . ARG D 1 31  ? -21.363 -7.194  -92.383  1.00 45.77  ? 24   ARG D NH1 1 
ATOM   10888 N NH2 . ARG D 1 31  ? -19.511 -5.878  -92.700  1.00 49.06  ? 24   ARG D NH2 1 
ATOM   10889 N N   . THR D 1 32  ? -19.749 -14.782 -92.150  1.00 25.78  ? 25   THR D N   1 
ATOM   10890 C CA  . THR D 1 32  ? -20.465 -16.078 -92.125  1.00 28.00  ? 25   THR D CA  1 
ATOM   10891 C C   . THR D 1 32  ? -19.474 -17.210 -91.894  1.00 29.63  ? 25   THR D C   1 
ATOM   10892 O O   . THR D 1 32  ? -18.295 -17.028 -92.227  1.00 28.83  ? 25   THR D O   1 
ATOM   10893 C CB  . THR D 1 32  ? -21.233 -16.314 -93.430  1.00 30.87  ? 25   THR D CB  1 
ATOM   10894 O OG1 . THR D 1 32  ? -20.338 -16.222 -94.543  1.00 28.02  ? 25   THR D OG1 1 
ATOM   10895 C CG2 . THR D 1 32  ? -22.371 -15.336 -93.617  1.00 32.12  ? 25   THR D CG2 1 
ATOM   10896 N N   . LEU D 1 33  ? -19.974 -18.305 -91.334  1.00 32.16  ? 26   LEU D N   1 
ATOM   10897 C CA  . LEU D 1 33  ? -19.204 -19.536 -91.049  1.00 33.47  ? 26   LEU D CA  1 
ATOM   10898 C C   . LEU D 1 33  ? -20.063 -20.715 -91.480  1.00 34.73  ? 26   LEU D C   1 
ATOM   10899 O O   . LEU D 1 33  ? -21.176 -20.799 -90.999  1.00 40.06  ? 26   LEU D O   1 
ATOM   10900 C CB  . LEU D 1 33  ? -18.913 -19.608 -89.548  1.00 31.12  ? 26   LEU D CB  1 
ATOM   10901 C CG  . LEU D 1 33  ? -18.096 -18.462 -88.970  1.00 30.68  ? 26   LEU D CG  1 
ATOM   10902 C CD1 . LEU D 1 33  ? -18.196 -18.438 -87.469  1.00 31.67  ? 26   LEU D CD1 1 
ATOM   10903 C CD2 . LEU D 1 33  ? -16.638 -18.541 -89.362  1.00 32.46  ? 26   LEU D CD2 1 
ATOM   10904 N N   . ASP D 1 34  ? -19.583 -21.579 -92.364  1.00 36.86  ? 27   ASP D N   1 
ATOM   10905 C CA  . ASP D 1 34  ? -20.275 -22.867 -92.631  1.00 38.20  ? 27   ASP D CA  1 
ATOM   10906 C C   . ASP D 1 34  ? -19.984 -23.763 -91.424  1.00 35.43  ? 27   ASP D C   1 
ATOM   10907 O O   . ASP D 1 34  ? -19.162 -23.369 -90.591  1.00 34.09  ? 27   ASP D O   1 
ATOM   10908 C CB  . ASP D 1 34  ? -19.921 -23.460 -94.007  1.00 39.02  ? 27   ASP D CB  1 
ATOM   10909 C CG  . ASP D 1 34  ? -18.478 -23.916 -94.173  1.00 41.26  ? 27   ASP D CG  1 
ATOM   10910 O OD1 . ASP D 1 34  ? -17.772 -24.078 -93.147  1.00 41.04  ? 27   ASP D OD1 1 
ATOM   10911 O OD2 . ASP D 1 34  ? -18.067 -24.095 -95.342  1.00 42.10  ? 27   ASP D OD2 1 
ATOM   10912 N N   . HIS D 1 35  ? -20.642 -24.914 -91.339  1.00 37.92  ? 28   HIS D N   1 
ATOM   10913 C CA  . HIS D 1 35  ? -20.483 -25.892 -90.232  1.00 43.28  ? 28   HIS D CA  1 
ATOM   10914 C C   . HIS D 1 35  ? -18.993 -26.149 -89.972  1.00 45.17  ? 28   HIS D C   1 
ATOM   10915 O O   . HIS D 1 35  ? -18.619 -26.212 -88.794  1.00 45.60  ? 28   HIS D O   1 
ATOM   10916 C CB  . HIS D 1 35  ? -21.249 -27.178 -90.546  1.00 47.78  ? 28   HIS D CB  1 
ATOM   10917 C CG  . HIS D 1 35  ? -21.339 -28.100 -89.385  1.00 49.86  ? 28   HIS D CG  1 
ATOM   10918 N ND1 . HIS D 1 35  ? -22.198 -27.863 -88.335  1.00 58.53  ? 28   HIS D ND1 1 
ATOM   10919 C CD2 . HIS D 1 35  ? -20.681 -29.243 -89.096  1.00 53.91  ? 28   HIS D CD2 1 
ATOM   10920 C CE1 . HIS D 1 35  ? -22.068 -28.818 -87.433  1.00 60.72  ? 28   HIS D CE1 1 
ATOM   10921 N NE2 . HIS D 1 35  ? -21.139 -29.680 -87.879  1.00 62.37  ? 28   HIS D NE2 1 
ATOM   10922 N N   . GLU D 1 36  ? -18.168 -26.268 -91.018  1.00 45.82  ? 29   GLU D N   1 
ATOM   10923 C CA  . GLU D 1 36  ? -16.731 -26.648 -90.901  1.00 47.71  ? 29   GLU D CA  1 
ATOM   10924 C C   . GLU D 1 36  ? -15.915 -25.477 -90.349  1.00 42.39  ? 29   GLU D C   1 
ATOM   10925 O O   . GLU D 1 36  ? -15.045 -25.731 -89.495  1.00 47.95  ? 29   GLU D O   1 
ATOM   10926 C CB  . GLU D 1 36  ? -16.161 -27.133 -92.241  1.00 57.36  ? 29   GLU D CB  1 
ATOM   10927 C CG  . GLU D 1 36  ? -16.607 -28.541 -92.608  1.00 63.91  ? 29   GLU D CG  1 
ATOM   10928 C CD  . GLU D 1 36  ? -16.617 -29.509 -91.435  1.00 70.49  ? 29   GLU D CD  1 
ATOM   10929 O OE1 . GLU D 1 36  ? -15.527 -29.735 -90.856  1.00 74.42  ? 29   GLU D OE1 1 
ATOM   10930 O OE2 . GLU D 1 36  ? -17.718 -30.004 -91.069  1.00 73.77  ? 29   GLU D OE2 1 
ATOM   10931 N N   . GLU D 1 37  ? -16.170 -24.254 -90.813  1.00 37.10  ? 30   GLU D N   1 
ATOM   10932 C CA  . GLU D 1 37  ? -15.427 -23.054 -90.355  1.00 36.07  ? 30   GLU D CA  1 
ATOM   10933 C C   . GLU D 1 37  ? -15.762 -22.816 -88.883  1.00 35.70  ? 30   GLU D C   1 
ATOM   10934 O O   . GLU D 1 37  ? -14.835 -22.526 -88.121  1.00 36.64  ? 30   GLU D O   1 
ATOM   10935 C CB  . GLU D 1 37  ? -15.777 -21.831 -91.195  1.00 37.59  ? 30   GLU D CB  1 
ATOM   10936 C CG  . GLU D 1 37  ? -15.248 -21.903 -92.615  1.00 39.77  ? 30   GLU D CG  1 
ATOM   10937 C CD  . GLU D 1 37  ? -15.909 -20.948 -93.602  1.00 40.94  ? 30   GLU D CD  1 
ATOM   10938 O OE1 . GLU D 1 37  ? -17.120 -20.720 -93.496  1.00 40.14  ? 30   GLU D OE1 1 
ATOM   10939 O OE2 . GLU D 1 37  ? -15.217 -20.428 -94.477  1.00 46.00  ? 30   GLU D OE2 1 
ATOM   10940 N N   . MET D 1 38  ? -17.043 -22.939 -88.529  1.00 34.42  ? 31   MET D N   1 
ATOM   10941 C CA  . MET D 1 38  ? -17.584 -22.812 -87.153  1.00 36.79  ? 31   MET D CA  1 
ATOM   10942 C C   . MET D 1 38  ? -16.912 -23.845 -86.247  1.00 37.80  ? 31   MET D C   1 
ATOM   10943 O O   . MET D 1 38  ? -16.416 -23.438 -85.188  1.00 41.21  ? 31   MET D O   1 
ATOM   10944 C CB  . MET D 1 38  ? -19.099 -23.040 -87.140  1.00 37.86  ? 31   MET D CB  1 
ATOM   10945 C CG  . MET D 1 38  ? -19.727 -23.029 -85.755  1.00 39.74  ? 31   MET D CG  1 
ATOM   10946 S SD  . MET D 1 38  ? -19.889 -24.674 -84.987  1.00 40.60  ? 31   MET D SD  1 
ATOM   10947 C CE  . MET D 1 38  ? -21.135 -25.396 -86.053  1.00 43.76  ? 31   MET D CE  1 
ATOM   10948 N N   . LYS D 1 39  ? -16.905 -25.123 -86.640  1.00 38.73  ? 32   LYS D N   1 
ATOM   10949 C CA  . LYS D 1 39  ? -16.382 -26.232 -85.797  1.00 38.85  ? 32   LYS D CA  1 
ATOM   10950 C C   . LYS D 1 39  ? -14.905 -25.978 -85.530  1.00 34.96  ? 32   LYS D C   1 
ATOM   10951 O O   . LYS D 1 39  ? -14.478 -26.192 -84.396  1.00 32.10  ? 32   LYS D O   1 
ATOM   10952 C CB  . LYS D 1 39  ? -16.566 -27.608 -86.438  1.00 46.74  ? 32   LYS D CB  1 
ATOM   10953 C CG  . LYS D 1 39  ? -17.563 -28.514 -85.728  1.00 58.36  ? 32   LYS D CG  1 
ATOM   10954 C CD  . LYS D 1 39  ? -18.066 -29.673 -86.567  1.00 68.84  ? 32   LYS D CD  1 
ATOM   10955 C CE  . LYS D 1 39  ? -16.967 -30.576 -87.100  1.00 76.28  ? 32   LYS D CE  1 
ATOM   10956 N NZ  . LYS D 1 39  ? -17.365 -31.160 -88.405  1.00 79.80  ? 32   LYS D NZ  1 
ATOM   10957 N N   . ALA D 1 40  ? -14.179 -25.504 -86.540  1.00 32.72  ? 33   ALA D N   1 
ATOM   10958 C CA  . ALA D 1 40  ? -12.726 -25.246 -86.474  1.00 34.00  ? 33   ALA D CA  1 
ATOM   10959 C C   . ALA D 1 40  ? -12.457 -24.050 -85.552  1.00 32.36  ? 33   ALA D C   1 
ATOM   10960 O O   . ALA D 1 40  ? -11.487 -24.134 -84.765  1.00 31.76  ? 33   ALA D O   1 
ATOM   10961 C CB  . ALA D 1 40  ? -12.170 -25.016 -87.860  1.00 34.41  ? 33   ALA D CB  1 
ATOM   10962 N N   . LEU D 1 41  ? -13.273 -22.995 -85.645  1.00 30.91  ? 34   LEU D N   1 
ATOM   10963 C CA  . LEU D 1 41  ? -13.071 -21.748 -84.862  1.00 33.19  ? 34   LEU D CA  1 
ATOM   10964 C C   . LEU D 1 41  ? -13.439 -21.993 -83.392  1.00 31.41  ? 34   LEU D C   1 
ATOM   10965 O O   . LEU D 1 41  ? -12.682 -21.571 -82.506  1.00 29.80  ? 34   LEU D O   1 
ATOM   10966 C CB  . LEU D 1 41  ? -13.910 -20.609 -85.441  1.00 34.17  ? 34   LEU D CB  1 
ATOM   10967 C CG  . LEU D 1 41  ? -13.940 -19.337 -84.593  1.00 35.23  ? 34   LEU D CG  1 
ATOM   10968 C CD1 . LEU D 1 41  ? -12.567 -18.694 -84.523  1.00 36.55  ? 34   LEU D CD1 1 
ATOM   10969 C CD2 . LEU D 1 41  ? -14.951 -18.354 -85.138  1.00 34.93  ? 34   LEU D CD2 1 
ATOM   10970 N N   . ASN D 1 42  ? -14.569 -22.642 -83.146  1.00 29.94  ? 35   ASN D N   1 
ATOM   10971 C CA  . ASN D 1 42  ? -14.987 -23.004 -81.770  1.00 32.32  ? 35   ASN D CA  1 
ATOM   10972 C C   . ASN D 1 42  ? -13.847 -23.787 -81.108  1.00 32.17  ? 35   ASN D C   1 
ATOM   10973 O O   . ASN D 1 42  ? -13.446 -23.410 -79.995  1.00 31.04  ? 35   ASN D O   1 
ATOM   10974 C CB  . ASN D 1 42  ? -16.330 -23.740 -81.771  1.00 32.44  ? 35   ASN D CB  1 
ATOM   10975 C CG  . ASN D 1 42  ? -17.516 -22.815 -81.924  1.00 32.55  ? 35   ASN D CG  1 
ATOM   10976 O OD1 . ASN D 1 42  ? -17.422 -21.760 -82.529  1.00 28.87  ? 35   ASN D OD1 1 
ATOM   10977 N ND2 . ASN D 1 42  ? -18.643 -23.197 -81.362  1.00 38.03  ? 35   ASN D ND2 1 
ATOM   10978 N N   . ARG D 1 43  ? -13.334 -24.811 -81.788  1.00 33.33  ? 36   ARG D N   1 
ATOM   10979 C CA  . ARG D 1 43  ? -12.279 -25.731 -81.287  1.00 36.91  ? 36   ARG D CA  1 
ATOM   10980 C C   . ARG D 1 43  ? -11.022 -24.905 -80.968  1.00 35.09  ? 36   ARG D C   1 
ATOM   10981 O O   . ARG D 1 43  ? -10.393 -25.158 -79.925  1.00 38.15  ? 36   ARG D O   1 
ATOM   10982 C CB  . ARG D 1 43  ? -12.053 -26.848 -82.318  1.00 45.24  ? 36   ARG D CB  1 
ATOM   10983 C CG  . ARG D 1 43  ? -10.990 -27.878 -81.957  1.00 52.93  ? 36   ARG D CG  1 
ATOM   10984 C CD  . ARG D 1 43  ? -11.092 -29.168 -82.764  1.00 58.79  ? 36   ARG D CD  1 
ATOM   10985 N NE  . ARG D 1 43  ? -11.060 -28.972 -84.218  1.00 68.58  ? 36   ARG D NE  1 
ATOM   10986 C CZ  . ARG D 1 43  ? -12.081 -29.174 -85.073  1.00 71.73  ? 36   ARG D CZ  1 
ATOM   10987 N NH1 . ARG D 1 43  ? -13.272 -29.567 -84.647  1.00 76.35  ? 36   ARG D NH1 1 
ATOM   10988 N NH2 . ARG D 1 43  ? -11.920 -28.954 -86.369  1.00 63.66  ? 36   ARG D NH2 1 
ATOM   10989 N N   . GLU D 1 44  ? -10.689 -23.923 -81.803  1.00 32.77  ? 37   GLU D N   1 
ATOM   10990 C CA  . GLU D 1 44  ? -9.515  -23.033 -81.605  1.00 32.48  ? 37   GLU D CA  1 
ATOM   10991 C C   . GLU D 1 44  ? -9.728  -22.156 -80.374  1.00 30.41  ? 37   GLU D C   1 
ATOM   10992 O O   . GLU D 1 44  ? -8.822  -22.108 -79.529  1.00 31.70  ? 37   GLU D O   1 
ATOM   10993 C CB  . GLU D 1 44  ? -9.283  -22.127 -82.813  1.00 35.61  ? 37   GLU D CB  1 
ATOM   10994 C CG  . GLU D 1 44  ? -8.124  -22.561 -83.688  1.00 37.11  ? 37   GLU D CG  1 
ATOM   10995 C CD  . GLU D 1 44  ? -7.937  -21.689 -84.916  1.00 39.64  ? 37   GLU D CD  1 
ATOM   10996 O OE1 . GLU D 1 44  ? -8.940  -21.483 -85.621  1.00 38.34  ? 37   GLU D OE1 1 
ATOM   10997 O OE2 . GLU D 1 44  ? -6.795  -21.197 -85.146  1.00 44.04  ? 37   GLU D OE2 1 
ATOM   10998 N N   . VAL D 1 45  ? -10.874 -21.479 -80.289  1.00 27.60  ? 38   VAL D N   1 
ATOM   10999 C CA  . VAL D 1 45  ? -11.152 -20.473 -79.225  1.00 27.33  ? 38   VAL D CA  1 
ATOM   11000 C C   . VAL D 1 45  ? -11.084 -21.176 -77.858  1.00 26.94  ? 38   VAL D C   1 
ATOM   11001 O O   . VAL D 1 45  ? -10.522 -20.597 -76.927  1.00 26.67  ? 38   VAL D O   1 
ATOM   11002 C CB  . VAL D 1 45  ? -12.493 -19.741 -79.462  1.00 27.91  ? 38   VAL D CB  1 
ATOM   11003 C CG1 . VAL D 1 45  ? -12.940 -18.938 -78.237  1.00 29.32  ? 38   VAL D CG1 1 
ATOM   11004 C CG2 . VAL D 1 45  ? -12.416 -18.832 -80.676  1.00 27.47  ? 38   VAL D CG2 1 
ATOM   11005 N N   . ILE D 1 46  ? -11.585 -22.405 -77.750  1.00 28.06  ? 39   ILE D N   1 
ATOM   11006 C CA  . ILE D 1 46  ? -11.598 -23.171 -76.476  1.00 29.48  ? 39   ILE D CA  1 
ATOM   11007 C C   . ILE D 1 46  ? -10.164 -23.553 -76.125  1.00 31.90  ? 39   ILE D C   1 
ATOM   11008 O O   . ILE D 1 46  ? -9.788  -23.340 -74.962  1.00 36.03  ? 39   ILE D O   1 
ATOM   11009 C CB  . ILE D 1 46  ? -12.528 -24.393 -76.562  1.00 30.87  ? 39   ILE D CB  1 
ATOM   11010 C CG1 . ILE D 1 46  ? -13.989 -23.953 -76.647  1.00 32.12  ? 39   ILE D CG1 1 
ATOM   11011 C CG2 . ILE D 1 46  ? -12.310 -25.339 -75.392  1.00 31.72  ? 39   ILE D CG2 1 
ATOM   11012 C CD1 . ILE D 1 46  ? -14.939 -25.078 -76.972  1.00 34.69  ? 39   ILE D CD1 1 
ATOM   11013 N N   . GLU D 1 47  ? -9.406  -24.090 -77.080  1.00 32.01  ? 40   GLU D N   1 
ATOM   11014 C CA  . GLU D 1 47  ? -7.975  -24.437 -76.885  1.00 34.63  ? 40   GLU D CA  1 
ATOM   11015 C C   . GLU D 1 47  ? -7.220  -23.180 -76.425  1.00 33.36  ? 40   GLU D C   1 
ATOM   11016 O O   . GLU D 1 47  ? -6.484  -23.282 -75.417  1.00 32.54  ? 40   GLU D O   1 
ATOM   11017 C CB  . GLU D 1 47  ? -7.398  -25.053 -78.162  1.00 39.68  ? 40   GLU D CB  1 
ATOM   11018 C CG  . GLU D 1 47  ? -5.889  -25.272 -78.154  1.00 44.05  ? 40   GLU D CG  1 
ATOM   11019 C CD  . GLU D 1 47  ? -5.333  -26.298 -77.176  1.00 49.98  ? 40   GLU D CD  1 
ATOM   11020 O OE1 . GLU D 1 47  ? -6.133  -26.990 -76.496  1.00 53.96  ? 40   GLU D OE1 1 
ATOM   11021 O OE2 . GLU D 1 47  ? -4.077  -26.407 -77.095  1.00 56.60  ? 40   GLU D OE2 1 
ATOM   11022 N N   . TYR D 1 48  ? -7.416  -22.037 -77.091  1.00 30.59  ? 41   TYR D N   1 
ATOM   11023 C CA  . TYR D 1 48  ? -6.661  -20.789 -76.800  1.00 29.29  ? 41   TYR D CA  1 
ATOM   11024 C C   . TYR D 1 48  ? -7.126  -20.154 -75.471  1.00 29.71  ? 41   TYR D C   1 
ATOM   11025 O O   . TYR D 1 48  ? -6.271  -19.559 -74.786  1.00 28.14  ? 41   TYR D O   1 
ATOM   11026 C CB  . TYR D 1 48  ? -6.715  -19.799 -77.962  1.00 30.83  ? 41   TYR D CB  1 
ATOM   11027 C CG  . TYR D 1 48  ? -6.146  -20.295 -79.271  1.00 36.06  ? 41   TYR D CG  1 
ATOM   11028 C CD1 . TYR D 1 48  ? -5.352  -21.431 -79.344  1.00 40.17  ? 41   TYR D CD1 1 
ATOM   11029 C CD2 . TYR D 1 48  ? -6.385  -19.614 -80.454  1.00 40.11  ? 41   TYR D CD2 1 
ATOM   11030 C CE1 . TYR D 1 48  ? -4.844  -21.896 -80.549  1.00 41.44  ? 41   TYR D CE1 1 
ATOM   11031 C CE2 . TYR D 1 48  ? -5.893  -20.067 -81.674  1.00 42.18  ? 41   TYR D CE2 1 
ATOM   11032 C CZ  . TYR D 1 48  ? -5.128  -21.221 -81.728  1.00 43.32  ? 41   TYR D CZ  1 
ATOM   11033 O OH  . TYR D 1 48  ? -4.631  -21.667 -82.927  1.00 41.85  ? 41   TYR D OH  1 
ATOM   11034 N N   . PHE D 1 49  ? -8.405  -20.240 -75.080  1.00 28.02  ? 42   PHE D N   1 
ATOM   11035 C CA  . PHE D 1 49  ? -8.858  -19.742 -73.748  1.00 26.04  ? 42   PHE D CA  1 
ATOM   11036 C C   . PHE D 1 49  ? -8.111  -20.515 -72.664  1.00 25.93  ? 42   PHE D C   1 
ATOM   11037 O O   . PHE D 1 49  ? -7.581  -19.908 -71.732  1.00 24.65  ? 42   PHE D O   1 
ATOM   11038 C CB  . PHE D 1 49  ? -10.375 -19.851 -73.571  1.00 25.66  ? 42   PHE D CB  1 
ATOM   11039 C CG  . PHE D 1 49  ? -11.080 -18.522 -73.630  1.00 25.87  ? 42   PHE D CG  1 
ATOM   11040 C CD1 . PHE D 1 49  ? -11.487 -17.996 -74.850  1.00 24.76  ? 42   PHE D CD1 1 
ATOM   11041 C CD2 . PHE D 1 49  ? -11.311 -17.780 -72.472  1.00 24.51  ? 42   PHE D CD2 1 
ATOM   11042 C CE1 . PHE D 1 49  ? -12.121 -16.762 -74.916  1.00 24.67  ? 42   PHE D CE1 1 
ATOM   11043 C CE2 . PHE D 1 49  ? -11.933 -16.543 -72.542  1.00 25.04  ? 42   PHE D CE2 1 
ATOM   11044 C CZ  . PHE D 1 49  ? -12.347 -16.040 -73.760  1.00 26.21  ? 42   PHE D CZ  1 
ATOM   11045 N N   . LYS D 1 50  ? -8.050  -21.830 -72.851  1.00 29.56  ? 43   LYS D N   1 
ATOM   11046 C CA  . LYS D 1 50  ? -7.412  -22.825 -71.959  1.00 33.44  ? 43   LYS D CA  1 
ATOM   11047 C C   . LYS D 1 50  ? -5.903  -22.564 -71.875  1.00 33.32  ? 43   LYS D C   1 
ATOM   11048 O O   . LYS D 1 50  ? -5.357  -22.659 -70.757  1.00 35.08  ? 43   LYS D O   1 
ATOM   11049 C CB  . LYS D 1 50  ? -7.740  -24.210 -72.520  1.00 40.72  ? 43   LYS D CB  1 
ATOM   11050 C CG  . LYS D 1 50  ? -7.073  -25.400 -71.858  1.00 48.54  ? 43   LYS D CG  1 
ATOM   11051 C CD  . LYS D 1 50  ? -7.658  -26.705 -72.363  1.00 56.65  ? 43   LYS D CD  1 
ATOM   11052 C CE  . LYS D 1 50  ? -6.762  -27.883 -72.058  1.00 61.23  ? 43   LYS D CE  1 
ATOM   11053 N NZ  . LYS D 1 50  ? -5.659  -27.964 -73.038  1.00 65.27  ? 43   LYS D NZ  1 
ATOM   11054 N N   . GLU D 1 51  ? -5.240  -22.244 -72.992  1.00 30.03  ? 44   GLU D N   1 
ATOM   11055 C CA  . GLU D 1 51  ? -3.759  -22.207 -73.045  1.00 29.58  ? 44   GLU D CA  1 
ATOM   11056 C C   . GLU D 1 51  ? -3.223  -20.781 -72.875  1.00 27.41  ? 44   GLU D C   1 
ATOM   11057 O O   . GLU D 1 51  ? -1.996  -20.678 -72.618  1.00 26.18  ? 44   GLU D O   1 
ATOM   11058 C CB  . GLU D 1 51  ? -3.232  -22.789 -74.359  1.00 33.01  ? 44   GLU D CB  1 
ATOM   11059 C CG  . GLU D 1 51  ? -3.384  -24.289 -74.468  1.00 35.74  ? 44   GLU D CG  1 
ATOM   11060 C CD  . GLU D 1 51  ? -2.716  -25.084 -73.366  1.00 42.38  ? 44   GLU D CD  1 
ATOM   11061 O OE1 . GLU D 1 51  ? -1.543  -24.781 -73.025  1.00 46.52  ? 44   GLU D OE1 1 
ATOM   11062 O OE2 . GLU D 1 51  ? -3.367  -26.002 -72.847  1.00 49.13  ? 44   GLU D OE2 1 
ATOM   11063 N N   . HIS D 1 52  ? -4.036  -19.725 -73.023  1.00 24.02  ? 45   HIS D N   1 
ATOM   11064 C CA  . HIS D 1 52  ? -3.495  -18.339 -73.136  1.00 24.65  ? 45   HIS D CA  1 
ATOM   11065 C C   . HIS D 1 52  ? -4.341  -17.245 -72.472  1.00 23.28  ? 45   HIS D C   1 
ATOM   11066 O O   . HIS D 1 52  ? -3.845  -16.095 -72.402  1.00 22.85  ? 45   HIS D O   1 
ATOM   11067 C CB  . HIS D 1 52  ? -3.275  -18.003 -74.603  1.00 25.89  ? 45   HIS D CB  1 
ATOM   11068 C CG  . HIS D 1 52  ? -2.325  -18.937 -75.270  1.00 27.66  ? 45   HIS D CG  1 
ATOM   11069 N ND1 . HIS D 1 52  ? -1.023  -19.070 -74.858  1.00 27.92  ? 45   HIS D ND1 1 
ATOM   11070 C CD2 . HIS D 1 52  ? -2.489  -19.788 -76.308  1.00 28.34  ? 45   HIS D CD2 1 
ATOM   11071 C CE1 . HIS D 1 52  ? -0.412  -19.951 -75.628  1.00 29.43  ? 45   HIS D CE1 1 
ATOM   11072 N NE2 . HIS D 1 52  ? -1.287  -20.401 -76.535  1.00 28.42  ? 45   HIS D NE2 1 
ATOM   11073 N N   . VAL D 1 53  ? -5.547  -17.549 -71.996  1.00 22.73  ? 46   VAL D N   1 
ATOM   11074 C CA  . VAL D 1 53  ? -6.450  -16.535 -71.370  1.00 22.61  ? 46   VAL D CA  1 
ATOM   11075 C C   . VAL D 1 53  ? -6.719  -16.944 -69.919  1.00 22.32  ? 46   VAL D C   1 
ATOM   11076 O O   . VAL D 1 53  ? -6.254  -16.232 -69.016  1.00 20.61  ? 46   VAL D O   1 
ATOM   11077 C CB  . VAL D 1 53  ? -7.763  -16.360 -72.145  1.00 21.76  ? 46   VAL D CB  1 
ATOM   11078 C CG1 . VAL D 1 53  ? -8.550  -15.182 -71.596  1.00 22.52  ? 46   VAL D CG1 1 
ATOM   11079 C CG2 . VAL D 1 53  ? -7.531  -16.205 -73.637  1.00 23.27  ? 46   VAL D CG2 1 
ATOM   11080 N N   . ASN D 1 54  ? -7.456  -18.038 -69.717  1.00 22.05  ? 47   ASN D N   1 
ATOM   11081 C CA  . ASN D 1 54  ? -7.847  -18.512 -68.369  1.00 22.31  ? 47   ASN D CA  1 
ATOM   11082 C C   . ASN D 1 54  ? -8.670  -19.788 -68.490  1.00 23.64  ? 47   ASN D C   1 
ATOM   11083 O O   . ASN D 1 54  ? -9.848  -19.717 -68.807  1.00 26.96  ? 47   ASN D O   1 
ATOM   11084 C CB  . ASN D 1 54  ? -8.646  -17.442 -67.621  1.00 21.84  ? 47   ASN D CB  1 
ATOM   11085 C CG  . ASN D 1 54  ? -8.649  -17.661 -66.121  1.00 21.51  ? 47   ASN D CG  1 
ATOM   11086 O OD1 . ASN D 1 54  ? -8.741  -18.798 -65.643  1.00 20.64  ? 47   ASN D OD1 1 
ATOM   11087 N ND2 . ASN D 1 54  ? -8.582  -16.575 -65.376  1.00 19.95  ? 47   ASN D ND2 1 
ATOM   11088 N N   . PRO D 1 55  ? -8.129  -20.984 -68.177  1.00 24.56  ? 48   PRO D N   1 
ATOM   11089 C CA  . PRO D 1 55  ? -8.929  -22.209 -68.202  1.00 26.08  ? 48   PRO D CA  1 
ATOM   11090 C C   . PRO D 1 55  ? -10.060 -22.186 -67.167  1.00 28.70  ? 48   PRO D C   1 
ATOM   11091 O O   . PRO D 1 55  ? -10.993 -22.978 -67.304  1.00 33.53  ? 48   PRO D O   1 
ATOM   11092 C CB  . PRO D 1 55  ? -7.918  -23.305 -67.851  1.00 25.66  ? 48   PRO D CB  1 
ATOM   11093 C CG  . PRO D 1 55  ? -6.886  -22.574 -67.040  1.00 25.63  ? 48   PRO D CG  1 
ATOM   11094 C CD  . PRO D 1 55  ? -6.752  -21.237 -67.738  1.00 25.10  ? 48   PRO D CD  1 
ATOM   11095 N N   . GLY D 1 56  ? -9.944  -21.294 -66.174  1.00 28.31  ? 49   GLY D N   1 
ATOM   11096 C CA  . GLY D 1 56  ? -10.971 -21.024 -65.156  1.00 29.65  ? 49   GLY D CA  1 
ATOM   11097 C C   . GLY D 1 56  ? -12.273 -20.523 -65.753  1.00 31.01  ? 49   GLY D C   1 
ATOM   11098 O O   . GLY D 1 56  ? -13.327 -20.947 -65.261  1.00 30.43  ? 49   GLY D O   1 
ATOM   11099 N N   . PHE D 1 57  ? -12.213 -19.645 -66.763  1.00 33.06  ? 50   PHE D N   1 
ATOM   11100 C CA  . PHE D 1 57  ? -13.412 -19.083 -67.421  1.00 33.50  ? 50   PHE D CA  1 
ATOM   11101 C C   . PHE D 1 57  ? -14.192 -20.243 -68.062  1.00 34.74  ? 50   PHE D C   1 
ATOM   11102 O O   . PHE D 1 57  ? -15.413 -20.195 -67.993  1.00 35.00  ? 50   PHE D O   1 
ATOM   11103 C CB  . PHE D 1 57  ? -13.056 -17.891 -68.325  1.00 35.29  ? 50   PHE D CB  1 
ATOM   11104 C CG  . PHE D 1 57  ? -14.254 -17.010 -68.587  1.00 39.55  ? 50   PHE D CG  1 
ATOM   11105 C CD1 . PHE D 1 57  ? -14.840 -16.268 -67.565  1.00 40.64  ? 50   PHE D CD1 1 
ATOM   11106 C CD2 . PHE D 1 57  ? -14.906 -17.042 -69.819  1.00 41.80  ? 50   PHE D CD2 1 
ATOM   11107 C CE1 . PHE D 1 57  ? -16.018 -15.557 -67.788  1.00 44.71  ? 50   PHE D CE1 1 
ATOM   11108 C CE2 . PHE D 1 57  ? -16.067 -16.308 -70.046  1.00 39.97  ? 50   PHE D CE2 1 
ATOM   11109 C CZ  . PHE D 1 57  ? -16.624 -15.565 -69.034  1.00 39.67  ? 50   PHE D CZ  1 
ATOM   11110 N N   . LEU D 1 58  ? -13.536 -21.274 -68.602  1.00 35.80  ? 51   LEU D N   1 
ATOM   11111 C CA  . LEU D 1 58  ? -14.230 -22.446 -69.212  1.00 34.84  ? 51   LEU D CA  1 
ATOM   11112 C C   . LEU D 1 58  ? -14.924 -23.291 -68.132  1.00 38.45  ? 51   LEU D C   1 
ATOM   11113 O O   . LEU D 1 58  ? -15.990 -23.884 -68.428  1.00 36.31  ? 51   LEU D O   1 
ATOM   11114 C CB  . LEU D 1 58  ? -13.226 -23.295 -69.989  1.00 35.00  ? 51   LEU D CB  1 
ATOM   11115 C CG  . LEU D 1 58  ? -12.624 -22.616 -71.213  1.00 36.98  ? 51   LEU D CG  1 
ATOM   11116 C CD1 . LEU D 1 58  ? -11.467 -23.423 -71.770  1.00 38.28  ? 51   LEU D CD1 1 
ATOM   11117 C CD2 . LEU D 1 58  ? -13.679 -22.401 -72.280  1.00 37.19  ? 51   LEU D CD2 1 
ATOM   11118 N N   . GLU D 1 59  ? -14.352 -23.373 -66.930  1.00 40.00  ? 52   GLU D N   1 
ATOM   11119 C CA  . GLU D 1 59  ? -14.957 -24.147 -65.811  1.00 43.24  ? 52   GLU D CA  1 
ATOM   11120 C C   . GLU D 1 59  ? -16.207 -23.411 -65.310  1.00 39.35  ? 52   GLU D C   1 
ATOM   11121 O O   . GLU D 1 59  ? -17.187 -24.096 -65.039  1.00 33.83  ? 52   GLU D O   1 
ATOM   11122 C CB  . GLU D 1 59  ? -13.968 -24.374 -64.661  1.00 50.50  ? 52   GLU D CB  1 
ATOM   11123 C CG  . GLU D 1 59  ? -12.849 -25.347 -64.991  1.00 60.28  ? 52   GLU D CG  1 
ATOM   11124 C CD  . GLU D 1 59  ? -13.298 -26.705 -65.509  1.00 66.77  ? 52   GLU D CD  1 
ATOM   11125 O OE1 . GLU D 1 59  ? -13.968 -27.433 -64.756  1.00 72.21  ? 52   GLU D OE1 1 
ATOM   11126 O OE2 . GLU D 1 59  ? -12.985 -27.015 -66.667  1.00 77.57  ? 52   GLU D OE2 1 
ATOM   11127 N N   . TYR D 1 60  ? -16.150 -22.078 -65.168  1.00 39.36  ? 53   TYR D N   1 
ATOM   11128 C CA  . TYR D 1 60  ? -17.264 -21.220 -64.671  1.00 38.82  ? 53   TYR D CA  1 
ATOM   11129 C C   . TYR D 1 60  ? -18.457 -21.322 -65.619  1.00 33.63  ? 53   TYR D C   1 
ATOM   11130 O O   . TYR D 1 60  ? -19.563 -21.568 -65.145  1.00 32.12  ? 53   TYR D O   1 
ATOM   11131 C CB  . TYR D 1 60  ? -16.888 -19.740 -64.568  1.00 42.35  ? 53   TYR D CB  1 
ATOM   11132 C CG  . TYR D 1 60  ? -18.045 -18.778 -64.744  1.00 52.40  ? 53   TYR D CG  1 
ATOM   11133 C CD1 . TYR D 1 60  ? -18.975 -18.570 -63.729  1.00 59.19  ? 53   TYR D CD1 1 
ATOM   11134 C CD2 . TYR D 1 60  ? -18.226 -18.075 -65.932  1.00 59.06  ? 53   TYR D CD2 1 
ATOM   11135 C CE1 . TYR D 1 60  ? -20.031 -17.680 -63.874  1.00 61.41  ? 53   TYR D CE1 1 
ATOM   11136 C CE2 . TYR D 1 60  ? -19.264 -17.164 -66.088  1.00 63.52  ? 53   TYR D CE2 1 
ATOM   11137 C CZ  . TYR D 1 60  ? -20.164 -16.953 -65.047  1.00 64.04  ? 53   TYR D CZ  1 
ATOM   11138 O OH  . TYR D 1 60  ? -21.204 -16.069 -65.165  1.00 63.22  ? 53   TYR D OH  1 
ATOM   11139 N N   . ARG D 1 61  ? -18.223 -21.102 -66.911  1.00 35.56  ? 54   ARG D N   1 
ATOM   11140 C CA  . ARG D 1 61  ? -19.255 -21.114 -67.974  1.00 41.03  ? 54   ARG D CA  1 
ATOM   11141 C C   . ARG D 1 61  ? -19.966 -22.480 -68.016  1.00 42.94  ? 54   ARG D C   1 
ATOM   11142 O O   . ARG D 1 61  ? -21.151 -22.486 -68.367  1.00 43.25  ? 54   ARG D O   1 
ATOM   11143 C CB  . ARG D 1 61  ? -18.602 -20.721 -69.303  1.00 44.58  ? 54   ARG D CB  1 
ATOM   11144 C CG  . ARG D 1 61  ? -18.418 -19.219 -69.463  1.00 45.79  ? 54   ARG D CG  1 
ATOM   11145 C CD  . ARG D 1 61  ? -19.712 -18.555 -69.838  1.00 49.11  ? 54   ARG D CD  1 
ATOM   11146 N NE  . ARG D 1 61  ? -20.302 -19.255 -70.984  1.00 52.04  ? 54   ARG D NE  1 
ATOM   11147 C CZ  . ARG D 1 61  ? -21.595 -19.450 -71.171  1.00 49.62  ? 54   ARG D CZ  1 
ATOM   11148 N NH1 . ARG D 1 61  ? -22.479 -18.868 -70.382  1.00 47.11  ? 54   ARG D NH1 1 
ATOM   11149 N NH2 . ARG D 1 61  ? -22.010 -20.131 -72.230  1.00 53.74  ? 54   ARG D NH2 1 
ATOM   11150 N N   . LYS D 1 62  ? -19.285 -23.571 -67.626  1.00 44.42  ? 55   LYS D N   1 
ATOM   11151 C CA  . LYS D 1 62  ? -19.852 -24.952 -67.526  1.00 45.15  ? 55   LYS D CA  1 
ATOM   11152 C C   . LYS D 1 62  ? -20.864 -25.045 -66.376  1.00 44.95  ? 55   LYS D C   1 
ATOM   11153 O O   . LYS D 1 62  ? -21.938 -25.658 -66.611  1.00 44.98  ? 55   LYS D O   1 
ATOM   11154 C CB  . LYS D 1 62  ? -18.759 -26.012 -67.324  1.00 46.91  ? 55   LYS D CB  1 
ATOM   11155 C CG  . LYS D 1 62  ? -18.167 -26.595 -68.600  1.00 50.68  ? 55   LYS D CG  1 
ATOM   11156 C CD  . LYS D 1 62  ? -17.494 -27.945 -68.435  1.00 52.53  ? 55   LYS D CD  1 
ATOM   11157 C CE  . LYS D 1 62  ? -16.103 -27.826 -67.855  1.00 53.98  ? 55   LYS D CE  1 
ATOM   11158 N NZ  . LYS D 1 62  ? -15.064 -28.058 -68.882  1.00 53.96  ? 55   LYS D NZ  1 
ATOM   11159 N N   . SER D 1 63  ? -20.521 -24.478 -65.199  1.00 45.74  ? 56   SER D N   1 
ATOM   11160 C CA  . SER D 1 63  ? -21.336 -24.413 -63.947  1.00 42.55  ? 56   SER D CA  1 
ATOM   11161 C C   . SER D 1 63  ? -22.675 -23.698 -64.229  1.00 42.53  ? 56   SER D C   1 
ATOM   11162 O O   . SER D 1 63  ? -23.677 -23.972 -63.539  1.00 42.12  ? 56   SER D O   1 
ATOM   11163 C CB  . SER D 1 63  ? -20.557 -23.753 -62.769  1.00 37.60  ? 56   SER D CB  1 
ATOM   11164 O OG  . SER D 1 63  ? -20.586 -22.314 -62.802  1.00 33.08  ? 56   SER D OG  1 
ATOM   11165 N N   . VAL D 1 64  ? -22.688 -22.835 -65.228  1.00 44.76  ? 57   VAL D N   1 
ATOM   11166 C CA  . VAL D 1 64  ? -23.831 -21.960 -65.580  1.00 50.34  ? 57   VAL D CA  1 
ATOM   11167 C C   . VAL D 1 64  ? -24.349 -22.352 -67.002  1.00 53.48  ? 57   VAL D C   1 
ATOM   11168 O O   . VAL D 1 64  ? -24.912 -21.488 -67.720  1.00 49.88  ? 57   VAL D O   1 
ATOM   11169 C CB  . VAL D 1 64  ? -23.271 -20.537 -65.368  1.00 49.94  ? 57   VAL D CB  1 
ATOM   11170 C CG1 . VAL D 1 64  ? -22.014 -20.338 -66.198  1.00 49.56  ? 57   VAL D CG1 1 
ATOM   11171 C CG2 . VAL D 1 64  ? -24.271 -19.422 -65.569  1.00 52.02  ? 57   VAL D CG2 1 
ATOM   11172 N N   . THR D 1 65  ? -24.228 -23.639 -67.389  1.00 51.38  ? 58   THR D N   1 
ATOM   11173 C CA  . THR D 1 65  ? -24.737 -24.212 -68.675  1.00 55.01  ? 58   THR D CA  1 
ATOM   11174 C C   . THR D 1 65  ? -24.899 -25.743 -68.587  1.00 63.02  ? 58   THR D C   1 
ATOM   11175 O O   . THR D 1 65  ? -24.310 -26.360 -67.651  1.00 56.26  ? 58   THR D O   1 
ATOM   11176 C CB  . THR D 1 65  ? -23.812 -23.902 -69.869  1.00 47.92  ? 58   THR D CB  1 
ATOM   11177 O OG1 . THR D 1 65  ? -22.504 -24.399 -69.597  1.00 42.25  ? 58   THR D OG1 1 
ATOM   11178 C CG2 . THR D 1 65  ? -23.706 -22.434 -70.217  1.00 43.78  ? 58   THR D CG2 1 
ATOM   11179 N N   . ALA D 1 66  ? -25.653 -26.336 -69.531  1.00 66.32  ? 59   ALA D N   1 
ATOM   11180 C CA  . ALA D 1 66  ? -25.622 -27.791 -69.825  1.00 66.15  ? 59   ALA D CA  1 
ATOM   11181 C C   . ALA D 1 66  ? -24.551 -28.023 -70.892  1.00 69.35  ? 59   ALA D C   1 
ATOM   11182 O O   . ALA D 1 66  ? -24.790 -27.619 -72.035  1.00 68.78  ? 59   ALA D O   1 
ATOM   11183 C CB  . ALA D 1 66  ? -26.968 -28.309 -70.263  1.00 64.37  ? 59   ALA D CB  1 
ATOM   11184 N N   . GLY D 1 67  ? -23.402 -28.593 -70.499  1.00 74.34  ? 60   GLY D N   1 
ATOM   11185 C CA  . GLY D 1 67  ? -22.243 -28.955 -71.350  1.00 75.57  ? 60   GLY D CA  1 
ATOM   11186 C C   . GLY D 1 67  ? -22.518 -28.870 -72.839  1.00 74.70  ? 60   GLY D C   1 
ATOM   11187 O O   . GLY D 1 67  ? -23.622 -29.231 -73.256  1.00 72.49  ? 60   GLY D O   1 
ATOM   11188 N N   . GLY D 1 68  ? -21.536 -28.428 -73.629  1.00 79.68  ? 61   GLY D N   1 
ATOM   11189 C CA  . GLY D 1 68  ? -21.714 -28.122 -75.063  1.00 74.39  ? 61   GLY D CA  1 
ATOM   11190 C C   . GLY D 1 68  ? -22.214 -26.707 -75.262  1.00 68.54  ? 61   GLY D C   1 
ATOM   11191 O O   . GLY D 1 68  ? -21.774 -26.080 -76.227  1.00 75.10  ? 61   GLY D O   1 
ATOM   11192 N N   . ASP D 1 69  ? -23.069 -26.221 -74.354  1.00 63.77  ? 62   ASP D N   1 
ATOM   11193 C CA  . ASP D 1 69  ? -23.561 -24.816 -74.308  1.00 65.75  ? 62   ASP D CA  1 
ATOM   11194 C C   . ASP D 1 69  ? -22.479 -23.873 -73.753  1.00 63.07  ? 62   ASP D C   1 
ATOM   11195 O O   . ASP D 1 69  ? -22.482 -22.696 -74.148  1.00 63.02  ? 62   ASP D O   1 
ATOM   11196 C CB  . ASP D 1 69  ? -24.861 -24.686 -73.505  1.00 71.31  ? 62   ASP D CB  1 
ATOM   11197 C CG  . ASP D 1 69  ? -26.121 -24.613 -74.353  1.00 81.89  ? 62   ASP D CG  1 
ATOM   11198 O OD1 . ASP D 1 69  ? -26.039 -24.078 -75.490  1.00 82.87  ? 62   ASP D OD1 1 
ATOM   11199 O OD2 . ASP D 1 69  ? -27.196 -25.003 -73.841  1.00 91.02  ? 62   ASP D OD2 1 
ATOM   11200 N N   . TYR D 1 70  ? -21.591 -24.337 -72.866  1.00 61.52  ? 63   TYR D N   1 
ATOM   11201 C CA  . TYR D 1 70  ? -20.510 -23.500 -72.275  1.00 55.95  ? 63   TYR D CA  1 
ATOM   11202 C C   . TYR D 1 70  ? -19.602 -22.983 -73.393  1.00 58.18  ? 63   TYR D C   1 
ATOM   11203 O O   . TYR D 1 70  ? -19.084 -21.850 -73.266  1.00 56.13  ? 63   TYR D O   1 
ATOM   11204 C CB  . TYR D 1 70  ? -19.693 -24.293 -71.259  1.00 53.06  ? 63   TYR D CB  1 
ATOM   11205 C CG  . TYR D 1 70  ? -18.608 -25.136 -71.875  1.00 53.31  ? 63   TYR D CG  1 
ATOM   11206 C CD1 . TYR D 1 70  ? -18.878 -26.400 -72.370  1.00 56.92  ? 63   TYR D CD1 1 
ATOM   11207 C CD2 . TYR D 1 70  ? -17.309 -24.668 -71.973  1.00 50.87  ? 63   TYR D CD2 1 
ATOM   11208 C CE1 . TYR D 1 70  ? -17.883 -27.186 -72.936  1.00 58.10  ? 63   TYR D CE1 1 
ATOM   11209 C CE2 . TYR D 1 70  ? -16.303 -25.438 -72.537  1.00 56.70  ? 63   TYR D CE2 1 
ATOM   11210 C CZ  . TYR D 1 70  ? -16.587 -26.702 -73.027  1.00 58.18  ? 63   TYR D CZ  1 
ATOM   11211 O OH  . TYR D 1 70  ? -15.584 -27.450 -73.588  1.00 55.43  ? 63   TYR D OH  1 
ATOM   11212 N N   . GLY D 1 71  ? -19.437 -23.809 -74.441  1.00 60.22  ? 64   GLY D N   1 
ATOM   11213 C CA  . GLY D 1 71  ? -18.583 -23.572 -75.628  1.00 60.26  ? 64   GLY D CA  1 
ATOM   11214 C C   . GLY D 1 71  ? -19.318 -22.841 -76.739  1.00 56.23  ? 64   GLY D C   1 
ATOM   11215 O O   . GLY D 1 71  ? -19.122 -23.200 -77.937  1.00 58.91  ? 64   GLY D O   1 
ATOM   11216 N N   . ALA D 1 72  ? -20.163 -21.879 -76.349  1.00 47.50  ? 65   ALA D N   1 
ATOM   11217 C CA  . ALA D 1 72  ? -20.781 -20.875 -77.235  1.00 37.94  ? 65   ALA D CA  1 
ATOM   11218 C C   . ALA D 1 72  ? -19.785 -19.724 -77.391  1.00 35.81  ? 65   ALA D C   1 
ATOM   11219 O O   . ALA D 1 72  ? -19.244 -19.228 -76.357  1.00 28.77  ? 65   ALA D O   1 
ATOM   11220 C CB  . ALA D 1 72  ? -22.091 -20.406 -76.678  1.00 35.49  ? 65   ALA D CB  1 
ATOM   11221 N N   . VAL D 1 73  ? -19.542 -19.345 -78.651  1.00 31.49  ? 66   VAL D N   1 
ATOM   11222 C CA  . VAL D 1 73  ? -18.560 -18.300 -79.043  1.00 31.25  ? 66   VAL D CA  1 
ATOM   11223 C C   . VAL D 1 73  ? -19.329 -17.145 -79.678  1.00 29.17  ? 66   VAL D C   1 
ATOM   11224 O O   . VAL D 1 73  ? -20.012 -17.388 -80.675  1.00 29.52  ? 66   VAL D O   1 
ATOM   11225 C CB  . VAL D 1 73  ? -17.502 -18.881 -79.998  1.00 30.79  ? 66   VAL D CB  1 
ATOM   11226 C CG1 . VAL D 1 73  ? -16.405 -17.881 -80.290  1.00 30.57  ? 66   VAL D CG1 1 
ATOM   11227 C CG2 . VAL D 1 73  ? -16.929 -20.180 -79.458  1.00 31.07  ? 66   VAL D CG2 1 
ATOM   11228 N N   . GLU D 1 74  ? -19.205 -15.945 -79.110  1.00 29.99  ? 67   GLU D N   1 
ATOM   11229 C CA  . GLU D 1 74  ? -19.760 -14.683 -79.659  1.00 32.74  ? 67   GLU D CA  1 
ATOM   11230 C C   . GLU D 1 74  ? -19.305 -14.513 -81.098  1.00 30.47  ? 67   GLU D C   1 
ATOM   11231 O O   . GLU D 1 74  ? -18.153 -14.822 -81.345  1.00 31.16  ? 67   GLU D O   1 
ATOM   11232 C CB  . GLU D 1 74  ? -19.278 -13.461 -78.889  1.00 36.26  ? 67   GLU D CB  1 
ATOM   11233 C CG  . GLU D 1 74  ? -20.386 -12.811 -78.099  1.00 40.70  ? 67   GLU D CG  1 
ATOM   11234 C CD  . GLU D 1 74  ? -19.893 -11.992 -76.933  1.00 49.91  ? 67   GLU D CD  1 
ATOM   11235 O OE1 . GLU D 1 74  ? -18.657 -12.013 -76.653  1.00 56.26  ? 67   GLU D OE1 1 
ATOM   11236 O OE2 . GLU D 1 74  ? -20.751 -11.344 -76.310  1.00 54.97  ? 67   GLU D OE2 1 
ATOM   11237 N N   . TRP D 1 75  ? -20.179 -13.998 -81.968  1.00 28.02  ? 68   TRP D N   1 
ATOM   11238 C CA  . TRP D 1 75  ? -19.862 -13.772 -83.400  1.00 26.65  ? 68   TRP D CA  1 
ATOM   11239 C C   . TRP D 1 75  ? -20.257 -12.350 -83.830  1.00 26.21  ? 68   TRP D C   1 
ATOM   11240 O O   . TRP D 1 75  ? -19.383 -11.609 -84.308  1.00 21.38  ? 68   TRP D O   1 
ATOM   11241 C CB  . TRP D 1 75  ? -20.514 -14.864 -84.250  1.00 25.04  ? 68   TRP D CB  1 
ATOM   11242 C CG  . TRP D 1 75  ? -20.137 -14.781 -85.696  1.00 26.24  ? 68   TRP D CG  1 
ATOM   11243 C CD1 . TRP D 1 75  ? -20.984 -14.645 -86.749  1.00 26.26  ? 68   TRP D CD1 1 
ATOM   11244 C CD2 . TRP D 1 75  ? -18.808 -14.811 -86.255  1.00 27.01  ? 68   TRP D CD2 1 
ATOM   11245 N NE1 . TRP D 1 75  ? -20.280 -14.618 -87.920  1.00 26.62  ? 68   TRP D NE1 1 
ATOM   11246 C CE2 . TRP D 1 75  ? -18.945 -14.699 -87.647  1.00 27.21  ? 68   TRP D CE2 1 
ATOM   11247 C CE3 . TRP D 1 75  ? -17.518 -14.909 -85.719  1.00 27.61  ? 68   TRP D CE3 1 
ATOM   11248 C CZ2 . TRP D 1 75  ? -17.846 -14.695 -88.501  1.00 28.44  ? 68   TRP D CZ2 1 
ATOM   11249 C CZ3 . TRP D 1 75  ? -16.435 -14.886 -86.565  1.00 28.23  ? 68   TRP D CZ3 1 
ATOM   11250 C CH2 . TRP D 1 75  ? -16.599 -14.803 -87.937  1.00 27.54  ? 68   TRP D CH2 1 
ATOM   11251 N N   . GLN D 1 76  ? -21.519 -11.954 -83.648  1.00 29.12  ? 69   GLN D N   1 
ATOM   11252 C CA  . GLN D 1 76  ? -21.951 -10.578 -84.006  1.00 30.72  ? 69   GLN D CA  1 
ATOM   11253 C C   . GLN D 1 76  ? -23.270 -10.253 -83.316  1.00 28.79  ? 69   GLN D C   1 
ATOM   11254 O O   . GLN D 1 76  ? -23.931 -11.174 -82.823  1.00 27.24  ? 69   GLN D O   1 
ATOM   11255 C CB  . GLN D 1 76  ? -22.053 -10.400 -85.529  1.00 35.10  ? 69   GLN D CB  1 
ATOM   11256 C CG  . GLN D 1 76  ? -23.132 -11.245 -86.187  1.00 38.53  ? 69   GLN D CG  1 
ATOM   11257 C CD  . GLN D 1 76  ? -23.050 -11.229 -87.702  1.00 44.38  ? 69   GLN D CD  1 
ATOM   11258 O OE1 . GLN D 1 76  ? -22.527 -10.298 -88.333  1.00 48.26  ? 69   GLN D OE1 1 
ATOM   11259 N NE2 . GLN D 1 76  ? -23.608 -12.265 -88.314  1.00 46.71  ? 69   GLN D NE2 1 
ATOM   11260 N N   . ALA D 1 77  ? -23.576 -8.955  -83.258  1.00 29.01  ? 70   ALA D N   1 
ATOM   11261 C CA  . ALA D 1 77  ? -24.891 -8.371  -82.929  1.00 30.35  ? 70   ALA D CA  1 
ATOM   11262 C C   . ALA D 1 77  ? -25.918 -8.856  -83.956  1.00 30.35  ? 70   ALA D C   1 
ATOM   11263 O O   . ALA D 1 77  ? -25.596 -8.818  -85.147  1.00 32.91  ? 70   ALA D O   1 
ATOM   11264 C CB  . ALA D 1 77  ? -24.798 -6.864  -82.940  1.00 29.99  ? 70   ALA D CB  1 
ATOM   11265 N N   . GLY D 1 78  ? -27.095 -9.288  -83.498  1.00 29.93  ? 71   GLY D N   1 
ATOM   11266 C CA  . GLY D 1 78  ? -28.239 -9.662  -84.348  1.00 32.44  ? 71   GLY D CA  1 
ATOM   11267 C C   . GLY D 1 78  ? -29.072 -8.443  -84.701  1.00 33.69  ? 71   GLY D C   1 
ATOM   11268 O O   . GLY D 1 78  ? -28.921 -7.913  -85.798  1.00 45.45  ? 71   GLY D O   1 
ATOM   11269 N N   . SER D 1 79  ? -29.913 -7.998  -83.780  1.00 35.77  ? 72   SER D N   1 
ATOM   11270 C CA  . SER D 1 79  ? -30.662 -6.718  -83.837  1.00 35.31  ? 72   SER D CA  1 
ATOM   11271 C C   . SER D 1 79  ? -30.154 -5.848  -82.687  1.00 35.42  ? 72   SER D C   1 
ATOM   11272 O O   . SER D 1 79  ? -29.145 -6.256  -82.070  1.00 35.97  ? 72   SER D O   1 
ATOM   11273 C CB  . SER D 1 79  ? -32.133 -6.997  -83.730  1.00 36.23  ? 72   SER D CB  1 
ATOM   11274 O OG  . SER D 1 79  ? -32.377 -7.930  -82.683  1.00 35.86  ? 72   SER D OG  1 
ATOM   11275 N N   . LEU D 1 80  ? -30.824 -4.732  -82.374  1.00 33.21  ? 73   LEU D N   1 
ATOM   11276 C CA  . LEU D 1 80  ? -30.445 -3.861  -81.227  1.00 30.35  ? 73   LEU D CA  1 
ATOM   11277 C C   . LEU D 1 80  ? -30.264 -4.694  -79.961  1.00 26.87  ? 73   LEU D C   1 
ATOM   11278 O O   . LEU D 1 80  ? -29.373 -4.348  -79.184  1.00 28.24  ? 73   LEU D O   1 
ATOM   11279 C CB  . LEU D 1 80  ? -31.509 -2.793  -80.977  1.00 31.00  ? 73   LEU D CB  1 
ATOM   11280 C CG  . LEU D 1 80  ? -31.277 -1.454  -81.670  1.00 32.97  ? 73   LEU D CG  1 
ATOM   11281 C CD1 . LEU D 1 80  ? -32.513 -0.574  -81.545  1.00 35.35  ? 73   LEU D CD1 1 
ATOM   11282 C CD2 . LEU D 1 80  ? -30.055 -0.736  -81.115  1.00 31.14  ? 73   LEU D CD2 1 
ATOM   11283 N N   . ASN D 1 81  ? -31.084 -5.724  -79.751  1.00 23.56  ? 74   ASN D N   1 
ATOM   11284 C CA  . ASN D 1 81  ? -31.234 -6.358  -78.418  1.00 23.04  ? 74   ASN D CA  1 
ATOM   11285 C C   . ASN D 1 81  ? -30.834 -7.832  -78.458  1.00 22.62  ? 74   ASN D C   1 
ATOM   11286 O O   . ASN D 1 81  ? -31.099 -8.527  -77.460  1.00 21.65  ? 74   ASN D O   1 
ATOM   11287 C CB  . ASN D 1 81  ? -32.649 -6.174  -77.887  1.00 21.40  ? 74   ASN D CB  1 
ATOM   11288 C CG  . ASN D 1 81  ? -33.094 -4.730  -77.947  1.00 21.91  ? 74   ASN D CG  1 
ATOM   11289 O OD1 . ASN D 1 81  ? -32.364 -3.832  -77.527  1.00 20.07  ? 74   ASN D OD1 1 
ATOM   11290 N ND2 . ASN D 1 81  ? -34.290 -4.499  -78.480  1.00 23.90  ? 74   ASN D ND2 1 
ATOM   11291 N N   . THR D 1 82  ? -30.196 -8.296  -79.536  1.00 22.17  ? 75   THR D N   1 
ATOM   11292 C CA  . THR D 1 82  ? -29.812 -9.727  -79.651  1.00 23.43  ? 75   THR D CA  1 
ATOM   11293 C C   . THR D 1 82  ? -28.338 -9.909  -80.022  1.00 23.06  ? 75   THR D C   1 
ATOM   11294 O O   . THR D 1 82  ? -27.743 -8.997  -80.619  1.00 22.66  ? 75   THR D O   1 
ATOM   11295 C CB  . THR D 1 82  ? -30.721 -10.481 -80.622  1.00 23.13  ? 75   THR D CB  1 
ATOM   11296 O OG1 . THR D 1 82  ? -30.578 -9.898  -81.915  1.00 22.23  ? 75   THR D OG1 1 
ATOM   11297 C CG2 . THR D 1 82  ? -32.170 -10.447 -80.195  1.00 24.44  ? 75   THR D CG2 1 
ATOM   11298 N N   . LEU D 1 83  ? -27.804 -11.063 -79.622  1.00 23.66  ? 76   LEU D N   1 
ATOM   11299 C CA  . LEU D 1 83  ? -26.432 -11.540 -79.906  1.00 26.71  ? 76   LEU D CA  1 
ATOM   11300 C C   . LEU D 1 83  ? -26.528 -12.868 -80.646  1.00 25.45  ? 76   LEU D C   1 
ATOM   11301 O O   . LEU D 1 83  ? -27.411 -13.680 -80.313  1.00 20.92  ? 76   LEU D O   1 
ATOM   11302 C CB  . LEU D 1 83  ? -25.658 -11.718 -78.595  1.00 28.07  ? 76   LEU D CB  1 
ATOM   11303 C CG  . LEU D 1 83  ? -25.274 -10.413 -77.906  1.00 29.29  ? 76   LEU D CG  1 
ATOM   11304 C CD1 . LEU D 1 83  ? -24.472 -10.693 -76.655  1.00 32.34  ? 76   LEU D CD1 1 
ATOM   11305 C CD2 . LEU D 1 83  ? -24.477 -9.519  -78.830  1.00 29.11  ? 76   LEU D CD2 1 
ATOM   11306 N N   . VAL D 1 84  ? -25.609 -13.087 -81.578  1.00 26.29  ? 77   VAL D N   1 
ATOM   11307 C CA  . VAL D 1 84  ? -25.578 -14.311 -82.418  1.00 27.92  ? 77   VAL D CA  1 
ATOM   11308 C C   . VAL D 1 84  ? -24.226 -14.983 -82.196  1.00 28.54  ? 77   VAL D C   1 
ATOM   11309 O O   . VAL D 1 84  ? -23.197 -14.283 -82.332  1.00 28.69  ? 77   VAL D O   1 
ATOM   11310 C CB  . VAL D 1 84  ? -25.821 -13.965 -83.894  1.00 28.05  ? 77   VAL D CB  1 
ATOM   11311 C CG1 . VAL D 1 84  ? -25.873 -15.227 -84.739  1.00 30.51  ? 77   VAL D CG1 1 
ATOM   11312 C CG2 . VAL D 1 84  ? -27.083 -13.123 -84.066  1.00 28.57  ? 77   VAL D CG2 1 
ATOM   11313 N N   . ASP D 1 85  ? -24.247 -16.275 -81.843  1.00 28.20  ? 78   ASP D N   1 
ATOM   11314 C CA  . ASP D 1 85  ? -23.025 -17.107 -81.700  1.00 27.98  ? 78   ASP D CA  1 
ATOM   11315 C C   . ASP D 1 85  ? -22.608 -17.612 -83.086  1.00 27.03  ? 78   ASP D C   1 
ATOM   11316 O O   . ASP D 1 85  ? -23.296 -17.337 -84.076  1.00 24.89  ? 78   ASP D O   1 
ATOM   11317 C CB  . ASP D 1 85  ? -23.181 -18.239 -80.673  1.00 29.04  ? 78   ASP D CB  1 
ATOM   11318 C CG  . ASP D 1 85  ? -24.043 -19.431 -81.088  1.00 31.55  ? 78   ASP D CG  1 
ATOM   11319 O OD1 . ASP D 1 85  ? -24.433 -19.504 -82.274  1.00 33.51  ? 78   ASP D OD1 1 
ATOM   11320 O OD2 . ASP D 1 85  ? -24.333 -20.285 -80.203  1.00 33.14  ? 78   ASP D OD2 1 
ATOM   11321 N N   . THR D 1 86  ? -21.489 -18.329 -83.109  1.00 27.70  ? 79   THR D N   1 
ATOM   11322 C CA  . THR D 1 86  ? -20.829 -18.891 -84.303  1.00 26.31  ? 79   THR D CA  1 
ATOM   11323 C C   . THR D 1 86  ? -21.713 -19.949 -84.970  1.00 27.91  ? 79   THR D C   1 
ATOM   11324 O O   . THR D 1 86  ? -21.449 -20.232 -86.157  1.00 31.74  ? 79   THR D O   1 
ATOM   11325 C CB  . THR D 1 86  ? -19.457 -19.452 -83.919  1.00 25.98  ? 79   THR D CB  1 
ATOM   11326 O OG1 . THR D 1 86  ? -19.652 -20.345 -82.820  1.00 23.79  ? 79   THR D OG1 1 
ATOM   11327 C CG2 . THR D 1 86  ? -18.472 -18.355 -83.573  1.00 25.53  ? 79   THR D CG2 1 
ATOM   11328 N N   . GLN D 1 87  ? -22.706 -20.504 -84.272  1.00 26.74  ? 80   GLN D N   1 
ATOM   11329 C CA  . GLN D 1 87  ? -23.618 -21.547 -84.816  1.00 31.27  ? 80   GLN D CA  1 
ATOM   11330 C C   . GLN D 1 87  ? -24.913 -20.902 -85.335  1.00 32.62  ? 80   GLN D C   1 
ATOM   11331 O O   . GLN D 1 87  ? -25.799 -21.652 -85.792  1.00 31.18  ? 80   GLN D O   1 
ATOM   11332 C CB  . GLN D 1 87  ? -23.946 -22.589 -83.750  1.00 35.83  ? 80   GLN D CB  1 
ATOM   11333 C CG  . GLN D 1 87  ? -22.702 -23.155 -83.086  1.00 42.45  ? 80   GLN D CG  1 
ATOM   11334 C CD  . GLN D 1 87  ? -23.015 -24.268 -82.121  1.00 46.24  ? 80   GLN D CD  1 
ATOM   11335 O OE1 . GLN D 1 87  ? -23.180 -24.051 -80.916  1.00 44.70  ? 80   GLN D OE1 1 
ATOM   11336 N NE2 . GLN D 1 87  ? -23.096 -25.476 -82.661  1.00 47.95  ? 80   GLN D NE2 1 
ATOM   11337 N N   . GLY D 1 88  ? -25.015 -19.570 -85.269  1.00 32.34  ? 81   GLY D N   1 
ATOM   11338 C CA  . GLY D 1 88  ? -26.172 -18.792 -85.748  1.00 32.20  ? 81   GLY D CA  1 
ATOM   11339 C C   . GLY D 1 88  ? -27.307 -18.721 -84.736  1.00 32.21  ? 81   GLY D C   1 
ATOM   11340 O O   . GLY D 1 88  ? -28.382 -18.207 -85.104  1.00 29.22  ? 81   GLY D O   1 
ATOM   11341 N N   . GLN D 1 89  ? -27.096 -19.193 -83.506  1.00 33.46  ? 82   GLN D N   1 
ATOM   11342 C CA  . GLN D 1 89  ? -28.132 -19.128 -82.447  1.00 35.87  ? 82   GLN D CA  1 
ATOM   11343 C C   . GLN D 1 89  ? -28.197 -17.685 -81.927  1.00 35.51  ? 82   GLN D C   1 
ATOM   11344 O O   . GLN D 1 89  ? -27.141 -17.124 -81.573  1.00 35.14  ? 82   GLN D O   1 
ATOM   11345 C CB  . GLN D 1 89  ? -27.876 -20.202 -81.390  1.00 37.78  ? 82   GLN D CB  1 
ATOM   11346 C CG  . GLN D 1 89  ? -28.176 -21.623 -81.876  1.00 42.07  ? 82   GLN D CG  1 
ATOM   11347 C CD  . GLN D 1 89  ? -29.637 -21.958 -82.153  1.00 55.19  ? 82   GLN D CD  1 
ATOM   11348 O OE1 . GLN D 1 89  ? -30.544 -21.728 -81.330  1.00 55.98  ? 82   GLN D OE1 1 
ATOM   11349 N NE2 . GLN D 1 89  ? -29.885 -22.563 -83.315  1.00 58.14  ? 82   GLN D NE2 1 
ATOM   11350 N N   . GLU D 1 90  ? -29.394 -17.080 -81.978  1.00 33.66  ? 83   GLU D N   1 
ATOM   11351 C CA  . GLU D 1 90  ? -29.661 -15.665 -81.600  1.00 32.40  ? 83   GLU D CA  1 
ATOM   11352 C C   . GLU D 1 90  ? -30.138 -15.659 -80.144  1.00 29.78  ? 83   GLU D C   1 
ATOM   11353 O O   . GLU D 1 90  ? -30.969 -16.489 -79.806  1.00 29.33  ? 83   GLU D O   1 
ATOM   11354 C CB  . GLU D 1 90  ? -30.667 -15.031 -82.569  1.00 34.47  ? 83   GLU D CB  1 
ATOM   11355 C CG  . GLU D 1 90  ? -30.782 -13.509 -82.465  1.00 36.63  ? 83   GLU D CG  1 
ATOM   11356 C CD  . GLU D 1 90  ? -31.694 -12.820 -83.479  1.00 38.51  ? 83   GLU D CD  1 
ATOM   11357 O OE1 . GLU D 1 90  ? -32.771 -13.354 -83.742  1.00 41.14  ? 83   GLU D OE1 1 
ATOM   11358 O OE2 . GLU D 1 90  ? -31.337 -11.730 -83.994  1.00 41.58  ? 83   GLU D OE2 1 
ATOM   11359 N N   . PHE D 1 91  ? -29.564 -14.797 -79.310  1.00 27.99  ? 84   PHE D N   1 
ATOM   11360 C CA  . PHE D 1 91  ? -29.883 -14.663 -77.876  1.00 26.34  ? 84   PHE D CA  1 
ATOM   11361 C C   . PHE D 1 91  ? -30.522 -13.302 -77.670  1.00 25.16  ? 84   PHE D C   1 
ATOM   11362 O O   . PHE D 1 91  ? -30.021 -12.332 -78.219  1.00 21.53  ? 84   PHE D O   1 
ATOM   11363 C CB  . PHE D 1 91  ? -28.626 -14.763 -77.012  1.00 28.65  ? 84   PHE D CB  1 
ATOM   11364 C CG  . PHE D 1 91  ? -27.998 -16.130 -77.021  1.00 29.20  ? 84   PHE D CG  1 
ATOM   11365 C CD1 . PHE D 1 91  ? -27.222 -16.532 -78.092  1.00 30.90  ? 84   PHE D CD1 1 
ATOM   11366 C CD2 . PHE D 1 91  ? -28.221 -17.029 -75.993  1.00 28.66  ? 84   PHE D CD2 1 
ATOM   11367 C CE1 . PHE D 1 91  ? -26.655 -17.796 -78.115  1.00 31.63  ? 84   PHE D CE1 1 
ATOM   11368 C CE2 . PHE D 1 91  ? -27.653 -18.290 -76.016  1.00 29.26  ? 84   PHE D CE2 1 
ATOM   11369 C CZ  . PHE D 1 91  ? -26.885 -18.677 -77.084  1.00 31.35  ? 84   PHE D CZ  1 
ATOM   11370 N N   . ILE D 1 92  ? -31.596 -13.250 -76.898  1.00 25.97  ? 85   ILE D N   1 
ATOM   11371 C CA  . ILE D 1 92  ? -32.097 -11.966 -76.341  1.00 27.66  ? 85   ILE D CA  1 
ATOM   11372 C C   . ILE D 1 92  ? -31.147 -11.608 -75.197  1.00 26.91  ? 85   ILE D C   1 
ATOM   11373 O O   . ILE D 1 92  ? -30.823 -12.511 -74.409  1.00 26.07  ? 85   ILE D O   1 
ATOM   11374 C CB  . ILE D 1 92  ? -33.566 -12.075 -75.898  1.00 28.38  ? 85   ILE D CB  1 
ATOM   11375 C CG1 . ILE D 1 92  ? -34.502 -12.317 -77.086  1.00 28.45  ? 85   ILE D CG1 1 
ATOM   11376 C CG2 . ILE D 1 92  ? -33.961 -10.846 -75.108  1.00 28.89  ? 85   ILE D CG2 1 
ATOM   11377 C CD1 . ILE D 1 92  ? -35.847 -12.879 -76.685  1.00 29.88  ? 85   ILE D CD1 1 
ATOM   11378 N N   . ASP D 1 93  ? -30.681 -10.359 -75.155  1.00 27.02  ? 86   ASP D N   1 
ATOM   11379 C CA  . ASP D 1 93  ? -29.625 -9.908  -74.211  1.00 27.64  ? 86   ASP D CA  1 
ATOM   11380 C C   . ASP D 1 93  ? -30.258 -9.246  -72.985  1.00 27.61  ? 86   ASP D C   1 
ATOM   11381 O O   . ASP D 1 93  ? -30.628 -8.070  -73.066  1.00 29.04  ? 86   ASP D O   1 
ATOM   11382 C CB  . ASP D 1 93  ? -28.626 -8.974  -74.893  1.00 27.01  ? 86   ASP D CB  1 
ATOM   11383 C CG  . ASP D 1 93  ? -27.425 -8.676  -74.019  1.00 26.59  ? 86   ASP D CG  1 
ATOM   11384 O OD1 . ASP D 1 93  ? -27.395 -9.186  -72.866  1.00 25.50  ? 86   ASP D OD1 1 
ATOM   11385 O OD2 . ASP D 1 93  ? -26.521 -7.954  -74.494  1.00 25.47  ? 86   ASP D OD2 1 
ATOM   11386 N N   . CYS D 1 94  ? -30.335 -9.983  -71.878  1.00 28.00  ? 87   CYS D N   1 
ATOM   11387 C CA  . CYS D 1 94  ? -30.727 -9.480  -70.535  1.00 28.74  ? 87   CYS D CA  1 
ATOM   11388 C C   . CYS D 1 94  ? -29.520 -9.329  -69.602  1.00 28.88  ? 87   CYS D C   1 
ATOM   11389 O O   . CYS D 1 94  ? -29.733 -9.024  -68.411  1.00 33.05  ? 87   CYS D O   1 
ATOM   11390 C CB  . CYS D 1 94  ? -31.727 -10.437 -69.912  1.00 29.00  ? 87   CYS D CB  1 
ATOM   11391 S SG  . CYS D 1 94  ? -33.326 -10.291 -70.736  1.00 30.61  ? 87   CYS D SG  1 
ATOM   11392 N N   . LEU D 1 95  ? -28.315 -9.579  -70.109  1.00 28.69  ? 88   LEU D N   1 
ATOM   11393 C CA  . LEU D 1 95  ? -27.045 -9.310  -69.399  1.00 29.85  ? 88   LEU D CA  1 
ATOM   11394 C C   . LEU D 1 95  ? -26.634 -7.850  -69.650  1.00 29.86  ? 88   LEU D C   1 
ATOM   11395 O O   . LEU D 1 95  ? -26.173 -7.184  -68.692  1.00 29.01  ? 88   LEU D O   1 
ATOM   11396 C CB  . LEU D 1 95  ? -26.006 -10.310 -69.897  1.00 31.71  ? 88   LEU D CB  1 
ATOM   11397 C CG  . LEU D 1 95  ? -24.644 -10.232 -69.207  1.00 36.32  ? 88   LEU D CG  1 
ATOM   11398 C CD1 . LEU D 1 95  ? -24.791 -10.177 -67.689  1.00 39.53  ? 88   LEU D CD1 1 
ATOM   11399 C CD2 . LEU D 1 95  ? -23.761 -11.401 -69.615  1.00 36.40  ? 88   LEU D CD2 1 
ATOM   11400 N N   . GLY D 1 96  ? -26.816 -7.371  -70.888  1.00 30.92  ? 89   GLY D N   1 
ATOM   11401 C CA  . GLY D 1 96  ? -26.464 -6.006  -71.337  1.00 29.94  ? 89   GLY D CA  1 
ATOM   11402 C C   . GLY D 1 96  ? -24.993 -5.691  -71.126  1.00 30.02  ? 89   GLY D C   1 
ATOM   11403 O O   . GLY D 1 96  ? -24.658 -4.511  -70.885  1.00 29.35  ? 89   GLY D O   1 
ATOM   11404 N N   . GLY D 1 97  ? -24.126 -6.698  -71.238  1.00 31.96  ? 90   GLY D N   1 
ATOM   11405 C CA  . GLY D 1 97  ? -22.696 -6.548  -70.914  1.00 33.72  ? 90   GLY D CA  1 
ATOM   11406 C C   . GLY D 1 97  ? -22.518 -5.908  -69.542  1.00 35.26  ? 90   GLY D C   1 
ATOM   11407 O O   . GLY D 1 97  ? -21.615 -5.079  -69.384  1.00 35.60  ? 90   GLY D O   1 
ATOM   11408 N N   . PHE D 1 98  ? -23.367 -6.247  -68.571  1.00 35.72  ? 91   PHE D N   1 
ATOM   11409 C CA  . PHE D 1 98  ? -23.250 -5.756  -67.175  1.00 35.97  ? 91   PHE D CA  1 
ATOM   11410 C C   . PHE D 1 98  ? -23.505 -4.241  -67.137  1.00 33.50  ? 91   PHE D C   1 
ATOM   11411 O O   . PHE D 1 98  ? -22.941 -3.560  -66.250  1.00 31.98  ? 91   PHE D O   1 
ATOM   11412 C CB  . PHE D 1 98  ? -21.891 -6.177  -66.597  1.00 37.55  ? 91   PHE D CB  1 
ATOM   11413 C CG  . PHE D 1 98  ? -21.690 -7.676  -66.523  1.00 41.72  ? 91   PHE D CG  1 
ATOM   11414 C CD1 . PHE D 1 98  ? -22.123 -8.402  -65.419  1.00 41.82  ? 91   PHE D CD1 1 
ATOM   11415 C CD2 . PHE D 1 98  ? -21.099 -8.377  -67.569  1.00 46.38  ? 91   PHE D CD2 1 
ATOM   11416 C CE1 . PHE D 1 98  ? -21.956 -9.780  -65.346  1.00 43.37  ? 91   PHE D CE1 1 
ATOM   11417 C CE2 . PHE D 1 98  ? -20.934 -9.758  -67.499  1.00 48.13  ? 91   PHE D CE2 1 
ATOM   11418 C CZ  . PHE D 1 98  ? -21.354 -10.456 -66.384  1.00 46.73  ? 91   PHE D CZ  1 
ATOM   11419 N N   . GLY D 1 99  ? -24.368 -3.747  -68.040  1.00 30.43  ? 92   GLY D N   1 
ATOM   11420 C CA  . GLY D 1 99  ? -24.868 -2.357  -68.033  1.00 27.81  ? 92   GLY D CA  1 
ATOM   11421 C C   . GLY D 1 99  ? -24.168 -1.464  -69.037  1.00 25.79  ? 92   GLY D C   1 
ATOM   11422 O O   . GLY D 1 99  ? -24.176 -0.237  -68.850  1.00 22.73  ? 92   GLY D O   1 
ATOM   11423 N N   . ILE D 1 100 ? -23.608 -2.052  -70.087  1.00 25.86  ? 93   ILE D N   1 
ATOM   11424 C CA  . ILE D 1 100 ? -22.907 -1.313  -71.171  1.00 28.61  ? 93   ILE D CA  1 
ATOM   11425 C C   . ILE D 1 100 ? -23.892 -0.936  -72.278  1.00 28.02  ? 93   ILE D C   1 
ATOM   11426 O O   . ILE D 1 100 ? -23.835 0.210   -72.756  1.00 26.85  ? 93   ILE D O   1 
ATOM   11427 C CB  . ILE D 1 100 ? -21.786 -2.186  -71.731  1.00 33.12  ? 93   ILE D CB  1 
ATOM   11428 C CG1 . ILE D 1 100 ? -20.754 -2.514  -70.652  1.00 36.50  ? 93   ILE D CG1 1 
ATOM   11429 C CG2 . ILE D 1 100 ? -21.145 -1.541  -72.942  1.00 33.12  ? 93   ILE D CG2 1 
ATOM   11430 C CD1 . ILE D 1 100 ? -19.814 -3.614  -71.073  1.00 42.76  ? 93   ILE D CD1 1 
ATOM   11431 N N   . PHE D 1 101 ? -24.732 -1.888  -72.685  1.00 27.87  ? 94   PHE D N   1 
ATOM   11432 C CA  . PHE D 1 101 ? -25.532 -1.845  -73.939  1.00 27.50  ? 94   PHE D CA  1 
ATOM   11433 C C   . PHE D 1 101 ? -26.894 -1.188  -73.669  1.00 24.98  ? 94   PHE D C   1 
ATOM   11434 O O   . PHE D 1 101 ? -27.912 -1.763  -74.048  1.00 26.16  ? 94   PHE D O   1 
ATOM   11435 C CB  . PHE D 1 101 ? -25.668 -3.252  -74.533  1.00 27.47  ? 94   PHE D CB  1 
ATOM   11436 C CG  . PHE D 1 101 ? -24.359 -3.909  -74.894  1.00 27.14  ? 94   PHE D CG  1 
ATOM   11437 C CD1 . PHE D 1 101 ? -23.553 -3.376  -75.887  1.00 25.68  ? 94   PHE D CD1 1 
ATOM   11438 C CD2 . PHE D 1 101 ? -23.919 -5.045  -74.229  1.00 28.56  ? 94   PHE D CD2 1 
ATOM   11439 C CE1 . PHE D 1 101 ? -22.352 -3.975  -76.222  1.00 25.57  ? 94   PHE D CE1 1 
ATOM   11440 C CE2 . PHE D 1 101 ? -22.711 -5.635  -74.554  1.00 27.49  ? 94   PHE D CE2 1 
ATOM   11441 C CZ  . PHE D 1 101 ? -21.934 -5.101  -75.560  1.00 26.08  ? 94   PHE D CZ  1 
ATOM   11442 N N   . ASN D 1 102 ? -26.886 0.013   -73.081  1.00 22.22  ? 95   ASN D N   1 
ATOM   11443 C CA  . ASN D 1 102 ? -28.082 0.819   -72.725  1.00 19.79  ? 95   ASN D CA  1 
ATOM   11444 C C   . ASN D 1 102 ? -28.845 1.168   -73.996  1.00 20.23  ? 95   ASN D C   1 
ATOM   11445 O O   . ASN D 1 102 ? -30.104 1.109   -73.961  1.00 22.31  ? 95   ASN D O   1 
ATOM   11446 C CB  . ASN D 1 102 ? -27.714 2.082   -71.949  1.00 18.97  ? 95   ASN D CB  1 
ATOM   11447 C CG  . ASN D 1 102 ? -27.418 1.774   -70.489  1.00 18.76  ? 95   ASN D CG  1 
ATOM   11448 O OD1 . ASN D 1 102 ? -27.084 0.640   -70.147  1.00 18.03  ? 95   ASN D OD1 1 
ATOM   11449 N ND2 . ASN D 1 102 ? -27.555 2.767   -69.623  1.00 18.06  ? 95   ASN D ND2 1 
ATOM   11450 N N   . VAL D 1 103 ? -28.117 1.501   -75.067  1.00 17.70  ? 96   VAL D N   1 
ATOM   11451 C CA  . VAL D 1 103 ? -28.742 1.933   -76.348  1.00 18.63  ? 96   VAL D CA  1 
ATOM   11452 C C   . VAL D 1 103 ? -28.641 0.796   -77.377  1.00 17.10  ? 96   VAL D C   1 
ATOM   11453 O O   . VAL D 1 103 ? -28.759 1.068   -78.555  1.00 14.24  ? 96   VAL D O   1 
ATOM   11454 C CB  . VAL D 1 103 ? -28.149 3.266   -76.844  1.00 19.84  ? 96   VAL D CB  1 
ATOM   11455 C CG1 . VAL D 1 103 ? -28.384 4.388   -75.842  1.00 19.57  ? 96   VAL D CG1 1 
ATOM   11456 C CG2 . VAL D 1 103 ? -26.660 3.149   -77.153  1.00 22.28  ? 96   VAL D CG2 1 
ATOM   11457 N N   . GLY D 1 104 ? -28.469 -0.440  -76.903  1.00 18.20  ? 97   GLY D N   1 
ATOM   11458 C CA  . GLY D 1 104 ? -28.498 -1.656  -77.732  1.00 18.76  ? 97   GLY D CA  1 
ATOM   11459 C C   . GLY D 1 104 ? -27.147 -1.943  -78.376  1.00 20.48  ? 97   GLY D C   1 
ATOM   11460 O O   . GLY D 1 104 ? -26.178 -1.190  -78.134  1.00 17.61  ? 97   GLY D O   1 
ATOM   11461 N N   . HIS D 1 105 ? -27.116 -3.005  -79.191  1.00 23.28  ? 98   HIS D N   1 
ATOM   11462 C CA  . HIS D 1 105 ? -25.940 -3.526  -79.938  1.00 23.75  ? 98   HIS D CA  1 
ATOM   11463 C C   . HIS D 1 105 ? -25.867 -2.799  -81.282  1.00 24.34  ? 98   HIS D C   1 
ATOM   11464 O O   . HIS D 1 105 ? -26.878 -2.785  -82.004  1.00 27.49  ? 98   HIS D O   1 
ATOM   11465 C CB  . HIS D 1 105 ? -26.018 -5.058  -80.084  1.00 23.54  ? 98   HIS D CB  1 
ATOM   11466 C CG  . HIS D 1 105 ? -25.839 -5.789  -78.792  1.00 24.33  ? 98   HIS D CG  1 
ATOM   11467 N ND1 . HIS D 1 105 ? -24.592 -6.049  -78.259  1.00 24.53  ? 98   HIS D ND1 1 
ATOM   11468 C CD2 . HIS D 1 105 ? -26.737 -6.265  -77.893  1.00 23.04  ? 98   HIS D CD2 1 
ATOM   11469 C CE1 . HIS D 1 105 ? -24.733 -6.662  -77.096  1.00 24.28  ? 98   HIS D CE1 1 
ATOM   11470 N NE2 . HIS D 1 105 ? -26.039 -6.814  -76.857  1.00 22.84  ? 98   HIS D NE2 1 
ATOM   11471 N N   . ARG D 1 106 ? -24.707 -2.213  -81.589  1.00 24.43  ? 99   ARG D N   1 
ATOM   11472 C CA  . ARG D 1 106 ? -24.442 -1.469  -82.848  1.00 22.79  ? 99   ARG D CA  1 
ATOM   11473 C C   . ARG D 1 106 ? -25.578 -0.470  -83.047  1.00 21.21  ? 99   ARG D C   1 
ATOM   11474 O O   . ARG D 1 106 ? -26.261 -0.532  -84.073  1.00 19.36  ? 99   ARG D O   1 
ATOM   11475 C CB  . ARG D 1 106 ? -24.336 -2.427  -84.040  1.00 23.54  ? 99   ARG D CB  1 
ATOM   11476 C CG  . ARG D 1 106 ? -23.270 -3.499  -83.911  1.00 24.08  ? 99   ARG D CG  1 
ATOM   11477 C CD  . ARG D 1 106 ? -23.079 -4.239  -85.205  1.00 25.67  ? 99   ARG D CD  1 
ATOM   11478 N NE  . ARG D 1 106 ? -22.507 -3.358  -86.223  1.00 29.32  ? 99   ARG D NE  1 
ATOM   11479 C CZ  . ARG D 1 106 ? -23.155 -2.885  -87.280  1.00 29.13  ? 99   ARG D CZ  1 
ATOM   11480 N NH1 . ARG D 1 106 ? -24.419 -3.206  -87.466  1.00 32.00  ? 99   ARG D NH1 1 
ATOM   11481 N NH2 . ARG D 1 106 ? -22.543 -2.091  -88.145  1.00 29.26  ? 99   ARG D NH2 1 
ATOM   11482 N N   . ASN D 1 107 ? -25.811 0.387   -82.060  1.00 20.43  ? 100  ASN D N   1 
ATOM   11483 C CA  . ASN D 1 107 ? -26.794 1.475   -82.232  1.00 19.83  ? 100  ASN D CA  1 
ATOM   11484 C C   . ASN D 1 107 ? -26.334 2.290   -83.432  1.00 19.06  ? 100  ASN D C   1 
ATOM   11485 O O   . ASN D 1 107 ? -25.222 2.797   -83.468  1.00 19.31  ? 100  ASN D O   1 
ATOM   11486 C CB  . ASN D 1 107 ? -26.960 2.306   -80.968  1.00 20.13  ? 100  ASN D CB  1 
ATOM   11487 C CG  . ASN D 1 107 ? -28.008 3.370   -81.171  1.00 21.08  ? 100  ASN D CG  1 
ATOM   11488 O OD1 . ASN D 1 107 ? -27.831 4.263   -82.001  1.00 23.21  ? 100  ASN D OD1 1 
ATOM   11489 N ND2 . ASN D 1 107 ? -29.132 3.247   -80.487  1.00 21.91  ? 100  ASN D ND2 1 
ATOM   11490 N N   . PRO D 1 108 ? -27.157 2.403   -84.482  1.00 20.55  ? 101  PRO D N   1 
ATOM   11491 C CA  . PRO D 1 108 ? -26.685 2.960   -85.755  1.00 21.29  ? 101  PRO D CA  1 
ATOM   11492 C C   . PRO D 1 108 ? -26.162 4.394   -85.581  1.00 21.19  ? 101  PRO D C   1 
ATOM   11493 O O   . PRO D 1 108 ? -25.270 4.775   -86.323  1.00 19.37  ? 101  PRO D O   1 
ATOM   11494 C CB  . PRO D 1 108 ? -27.918 2.935   -86.682  1.00 19.76  ? 101  PRO D CB  1 
ATOM   11495 C CG  . PRO D 1 108 ? -28.820 1.894   -86.042  1.00 20.95  ? 101  PRO D CG  1 
ATOM   11496 C CD  . PRO D 1 108 ? -28.563 1.983   -84.538  1.00 20.09  ? 101  PRO D CD  1 
ATOM   11497 N N   . VAL D 1 109 ? -26.737 5.158   -84.643  1.00 21.12  ? 102  VAL D N   1 
ATOM   11498 C CA  . VAL D 1 109 ? -26.334 6.574   -84.401  1.00 21.12  ? 102  VAL D CA  1 
ATOM   11499 C C   . VAL D 1 109 ? -24.924 6.586   -83.802  1.00 21.31  ? 102  VAL D C   1 
ATOM   11500 O O   . VAL D 1 109 ? -24.111 7.448   -84.183  1.00 21.57  ? 102  VAL D O   1 
ATOM   11501 C CB  . VAL D 1 109 ? -27.350 7.304   -83.506  1.00 20.83  ? 102  VAL D CB  1 
ATOM   11502 C CG1 . VAL D 1 109 ? -26.819 8.644   -83.028  1.00 20.20  ? 102  VAL D CG1 1 
ATOM   11503 C CG2 . VAL D 1 109 ? -28.691 7.476   -84.216  1.00 21.45  ? 102  VAL D CG2 1 
ATOM   11504 N N   . VAL D 1 110 ? -24.647 5.656   -82.894  1.00 21.94  ? 103  VAL D N   1 
ATOM   11505 C CA  . VAL D 1 110 ? -23.328 5.556   -82.223  1.00 22.46  ? 103  VAL D CA  1 
ATOM   11506 C C   . VAL D 1 110 ? -22.345 5.009   -83.259  1.00 22.44  ? 103  VAL D C   1 
ATOM   11507 O O   . VAL D 1 110 ? -21.270 5.611   -83.443  1.00 23.88  ? 103  VAL D O   1 
ATOM   11508 C CB  . VAL D 1 110 ? -23.370 4.689   -80.947  1.00 24.05  ? 103  VAL D CB  1 
ATOM   11509 C CG1 . VAL D 1 110 ? -22.007 4.626   -80.269  1.00 24.50  ? 103  VAL D CG1 1 
ATOM   11510 C CG2 . VAL D 1 110 ? -24.405 5.177   -79.949  1.00 25.46  ? 103  VAL D CG2 1 
ATOM   11511 N N   . VAL D 1 111 ? -22.699 3.915   -83.925  1.00 20.42  ? 104  VAL D N   1 
ATOM   11512 C CA  . VAL D 1 111 ? -21.798 3.284   -84.921  1.00 19.60  ? 104  VAL D CA  1 
ATOM   11513 C C   . VAL D 1 111 ? -21.415 4.369   -85.917  1.00 19.44  ? 104  VAL D C   1 
ATOM   11514 O O   . VAL D 1 111 ? -20.226 4.515   -86.187  1.00 20.94  ? 104  VAL D O   1 
ATOM   11515 C CB  . VAL D 1 111 ? -22.452 2.057   -85.571  1.00 19.01  ? 104  VAL D CB  1 
ATOM   11516 C CG1 . VAL D 1 111 ? -21.706 1.587   -86.797  1.00 18.67  ? 104  VAL D CG1 1 
ATOM   11517 C CG2 . VAL D 1 111 ? -22.563 0.923   -84.561  1.00 19.93  ? 104  VAL D CG2 1 
ATOM   11518 N N   . SER D 1 112 ? -22.382 5.164   -86.351  1.00 19.42  ? 105  SER D N   1 
ATOM   11519 C CA  . SER D 1 112 ? -22.181 6.244   -87.350  1.00 19.47  ? 105  SER D CA  1 
ATOM   11520 C C   . SER D 1 112 ? -21.152 7.260   -86.854  1.00 17.91  ? 105  SER D C   1 
ATOM   11521 O O   . SER D 1 112 ? -20.284 7.637   -87.600  1.00 16.65  ? 105  SER D O   1 
ATOM   11522 C CB  . SER D 1 112 ? -23.466 6.948   -87.670  1.00 20.88  ? 105  SER D CB  1 
ATOM   11523 O OG  . SER D 1 112 ? -23.206 8.025   -88.569  1.00 21.53  ? 105  SER D OG  1 
ATOM   11524 N N   . ALA D 1 113 ? -21.289 7.727   -85.627  1.00 19.61  ? 106  ALA D N   1 
ATOM   11525 C CA  . ALA D 1 113 ? -20.427 8.788   -85.071  1.00 19.05  ? 106  ALA D CA  1 
ATOM   11526 C C   . ALA D 1 113 ? -18.994 8.269   -84.998  1.00 18.84  ? 106  ALA D C   1 
ATOM   11527 O O   . ALA D 1 113 ? -18.064 9.007   -85.397  1.00 18.95  ? 106  ALA D O   1 
ATOM   11528 C CB  . ALA D 1 113 ? -20.953 9.194   -83.725  1.00 20.51  ? 106  ALA D CB  1 
ATOM   11529 N N   . VAL D 1 114 ? -18.839 7.021   -84.565  1.00 18.85  ? 107  VAL D N   1 
ATOM   11530 C CA  . VAL D 1 114 ? -17.509 6.370   -84.417  1.00 20.33  ? 107  VAL D CA  1 
ATOM   11531 C C   . VAL D 1 114 ? -16.888 6.210   -85.817  1.00 20.98  ? 107  VAL D C   1 
ATOM   11532 O O   . VAL D 1 114 ? -15.739 6.677   -86.025  1.00 20.19  ? 107  VAL D O   1 
ATOM   11533 C CB  . VAL D 1 114 ? -17.653 5.044   -83.647  1.00 20.81  ? 107  VAL D CB  1 
ATOM   11534 C CG1 . VAL D 1 114 ? -16.413 4.169   -83.715  1.00 21.28  ? 107  VAL D CG1 1 
ATOM   11535 C CG2 . VAL D 1 114 ? -18.020 5.303   -82.206  1.00 21.21  ? 107  VAL D CG2 1 
ATOM   11536 N N   A GLN D 1 115 ? -17.619 5.596   -86.753  0.57 21.34  ? 108  GLN D N   1 
ATOM   11537 N N   B GLN D 1 115 ? -17.637 5.591   -86.738  0.43 20.89  ? 108  GLN D N   1 
ATOM   11538 C CA  A GLN D 1 115 ? -17.212 5.441   -88.174  0.57 22.38  ? 108  GLN D CA  1 
ATOM   11539 C CA  B GLN D 1 115 ? -17.258 5.419   -88.166  0.43 21.48  ? 108  GLN D CA  1 
ATOM   11540 C C   A GLN D 1 115 ? -16.726 6.782   -88.726  0.57 22.76  ? 108  GLN D C   1 
ATOM   11541 C C   B GLN D 1 115 ? -16.757 6.762   -88.728  0.43 22.12  ? 108  GLN D C   1 
ATOM   11542 O O   A GLN D 1 115 ? -15.658 6.793   -89.376  0.57 23.89  ? 108  GLN D O   1 
ATOM   11543 O O   B GLN D 1 115 ? -15.677 6.764   -89.358  0.43 22.99  ? 108  GLN D O   1 
ATOM   11544 C CB  A GLN D 1 115 ? -18.378 4.958   -89.030  0.57 23.07  ? 108  GLN D CB  1 
ATOM   11545 C CB  B GLN D 1 115 ? -18.447 4.858   -88.950  0.43 21.53  ? 108  GLN D CB  1 
ATOM   11546 C CG  A GLN D 1 115 ? -18.574 3.453   -89.013  0.57 24.09  ? 108  GLN D CG  1 
ATOM   11547 C CG  B GLN D 1 115 ? -18.103 4.312   -90.332  0.43 21.83  ? 108  GLN D CG  1 
ATOM   11548 C CD  A GLN D 1 115 ? -19.734 3.059   -89.894  0.57 24.97  ? 108  GLN D CD  1 
ATOM   11549 C CD  B GLN D 1 115 ? -17.072 3.206   -90.307  0.43 21.79  ? 108  GLN D CD  1 
ATOM   11550 O OE1 A GLN D 1 115 ? -20.662 3.838   -90.126  0.57 25.84  ? 108  GLN D OE1 1 
ATOM   11551 O OE1 B GLN D 1 115 ? -15.867 3.453   -90.304  0.43 21.78  ? 108  GLN D OE1 1 
ATOM   11552 N NE2 A GLN D 1 115 ? -19.723 1.810   -90.320  0.57 26.08  ? 108  GLN D NE2 1 
ATOM   11553 N NE2 B GLN D 1 115 ? -17.538 1.967   -90.324  0.43 21.71  ? 108  GLN D NE2 1 
ATOM   11554 N N   . ASN D 1 116 ? -17.488 7.856   -88.478  1.00 21.98  ? 109  ASN D N   1 
ATOM   11555 C CA  . ASN D 1 116 ? -17.204 9.215   -89.014  1.00 23.35  ? 109  ASN D CA  1 
ATOM   11556 C C   . ASN D 1 116 ? -15.885 9.740   -88.443  1.00 23.87  ? 109  ASN D C   1 
ATOM   11557 O O   . ASN D 1 116 ? -15.043 10.262  -89.242  1.00 26.78  ? 109  ASN D O   1 
ATOM   11558 C CB  . ASN D 1 116 ? -18.337 10.204  -88.736  1.00 25.32  ? 109  ASN D CB  1 
ATOM   11559 C CG  . ASN D 1 116 ? -19.450 10.152  -89.770  1.00 26.04  ? 109  ASN D CG  1 
ATOM   11560 O OD1 . ASN D 1 116 ? -19.217 10.005  -90.972  1.00 27.83  ? 109  ASN D OD1 1 
ATOM   11561 N ND2 . ASN D 1 116 ? -20.679 10.306  -89.323  1.00 27.37  ? 109  ASN D ND2 1 
ATOM   11562 N N   . GLN D 1 117 ? -15.683 9.587   -87.137  1.00 22.05  ? 110  GLN D N   1 
ATOM   11563 C CA  . GLN D 1 117 ? -14.462 10.089  -86.463  1.00 20.91  ? 110  GLN D CA  1 
ATOM   11564 C C   . GLN D 1 117 ? -13.264 9.208   -86.847  1.00 20.06  ? 110  GLN D C   1 
ATOM   11565 O O   . GLN D 1 117 ? -12.177 9.762   -87.066  1.00 20.16  ? 110  GLN D O   1 
ATOM   11566 C CB  . GLN D 1 117 ? -14.676 10.150  -84.954  1.00 20.85  ? 110  GLN D CB  1 
ATOM   11567 C CG  . GLN D 1 117 ? -13.614 10.973  -84.239  1.00 21.27  ? 110  GLN D CG  1 
ATOM   11568 C CD  . GLN D 1 117 ? -13.447 12.351  -84.839  1.00 21.46  ? 110  GLN D CD  1 
ATOM   11569 O OE1 . GLN D 1 117 ? -14.431 13.022  -85.189  1.00 18.91  ? 110  GLN D OE1 1 
ATOM   11570 N NE2 . GLN D 1 117 ? -12.186 12.774  -84.951  1.00 21.66  ? 110  GLN D NE2 1 
ATOM   11571 N N   . LEU D 1 118 ? -13.457 7.894   -86.963  1.00 18.93  ? 111  LEU D N   1 
ATOM   11572 C CA  . LEU D 1 118 ? -12.404 6.954   -87.427  1.00 18.53  ? 111  LEU D CA  1 
ATOM   11573 C C   . LEU D 1 118 ? -11.845 7.433   -88.775  1.00 19.79  ? 111  LEU D C   1 
ATOM   11574 O O   . LEU D 1 118 ? -10.626 7.295   -88.983  1.00 22.03  ? 111  LEU D O   1 
ATOM   11575 C CB  . LEU D 1 118 ? -13.004 5.548   -87.518  1.00 17.73  ? 111  LEU D CB  1 
ATOM   11576 C CG  . LEU D 1 118 ? -12.055 4.435   -87.964  1.00 17.29  ? 111  LEU D CG  1 
ATOM   11577 C CD1 . LEU D 1 118 ? -10.816 4.386   -87.096  1.00 17.53  ? 111  LEU D CD1 1 
ATOM   11578 C CD2 . LEU D 1 118 ? -12.728 3.077   -87.933  1.00 17.28  ? 111  LEU D CD2 1 
ATOM   11579 N N   . ALA D 1 119 ? -12.677 8.014   -89.645  1.00 20.58  ? 112  ALA D N   1 
ATOM   11580 C CA  . ALA D 1 119 ? -12.257 8.493   -90.979  1.00 21.46  ? 112  ALA D CA  1 
ATOM   11581 C C   . ALA D 1 119 ? -11.377 9.748   -90.866  1.00 23.79  ? 112  ALA D C   1 
ATOM   11582 O O   . ALA D 1 119 ? -10.667 10.025  -91.850  1.00 26.64  ? 112  ALA D O   1 
ATOM   11583 C CB  . ALA D 1 119 ? -13.461 8.751   -91.838  1.00 22.04  ? 112  ALA D CB  1 
ATOM   11584 N N   . LYS D 1 120 ? -11.401 10.476  -89.737  1.00 24.80  ? 113  LYS D N   1 
ATOM   11585 C CA  . LYS D 1 120 ? -10.594 11.715  -89.532  1.00 25.19  ? 113  LYS D CA  1 
ATOM   11586 C C   . LYS D 1 120 ? -9.387  11.471  -88.617  1.00 26.93  ? 113  LYS D C   1 
ATOM   11587 O O   . LYS D 1 120 ? -8.242  11.745  -89.060  1.00 25.20  ? 113  LYS D O   1 
ATOM   11588 C CB  . LYS D 1 120 ? -11.431 12.806  -88.874  1.00 25.35  ? 113  LYS D CB  1 
ATOM   11589 C CG  . LYS D 1 120 ? -12.417 13.480  -89.794  1.00 26.97  ? 113  LYS D CG  1 
ATOM   11590 C CD  . LYS D 1 120 ? -13.045 14.681  -89.154  1.00 28.04  ? 113  LYS D CD  1 
ATOM   11591 C CE  . LYS D 1 120 ? -14.453 14.388  -88.688  1.00 29.20  ? 113  LYS D CE  1 
ATOM   11592 N NZ  . LYS D 1 120 ? -14.952 15.437  -87.767  1.00 30.19  ? 113  LYS D NZ  1 
ATOM   11593 N N   . GLN D 1 121 ? -9.649  11.070  -87.364  1.00 27.09  ? 114  GLN D N   1 
ATOM   11594 C CA  . GLN D 1 121 ? -8.639  10.939  -86.284  1.00 27.78  ? 114  GLN D CA  1 
ATOM   11595 C C   . GLN D 1 121 ? -9.217  10.095  -85.145  1.00 27.02  ? 114  GLN D C   1 
ATOM   11596 O O   . GLN D 1 121 ? -10.016 10.598  -84.347  1.00 24.99  ? 114  GLN D O   1 
ATOM   11597 C CB  . GLN D 1 121 ? -8.235  12.323  -85.776  1.00 30.48  ? 114  GLN D CB  1 
ATOM   11598 C CG  . GLN D 1 121 ? -6.829  12.339  -85.204  1.00 32.32  ? 114  GLN D CG  1 
ATOM   11599 C CD  . GLN D 1 121 ? -6.576  13.469  -84.238  1.00 37.38  ? 114  GLN D CD  1 
ATOM   11600 O OE1 . GLN D 1 121 ? -7.491  14.130  -83.760  1.00 42.11  ? 114  GLN D OE1 1 
ATOM   11601 N NE2 . GLN D 1 121 ? -5.307  13.673  -83.910  1.00 41.81  ? 114  GLN D NE2 1 
ATOM   11602 N N   . PRO D 1 122 ? -8.864  8.789   -85.038  1.00 25.52  ? 115  PRO D N   1 
ATOM   11603 C CA  . PRO D 1 122 ? -9.393  7.933   -83.974  1.00 25.85  ? 115  PRO D CA  1 
ATOM   11604 C C   . PRO D 1 122 ? -8.747  8.176   -82.596  1.00 26.66  ? 115  PRO D C   1 
ATOM   11605 O O   . PRO D 1 122 ? -9.478  8.226   -81.612  1.00 24.84  ? 115  PRO D O   1 
ATOM   11606 C CB  . PRO D 1 122 ? -9.092  6.515   -84.487  1.00 24.48  ? 115  PRO D CB  1 
ATOM   11607 C CG  . PRO D 1 122 ? -7.868  6.671   -85.341  1.00 23.82  ? 115  PRO D CG  1 
ATOM   11608 C CD  . PRO D 1 122 ? -7.960  8.062   -85.935  1.00 24.65  ? 115  PRO D CD  1 
ATOM   11609 N N   . LEU D 1 123 ? -7.417  8.312   -82.546  1.00 26.20  ? 116  LEU D N   1 
ATOM   11610 C CA  . LEU D 1 123 ? -6.667  8.678   -81.308  1.00 27.46  ? 116  LEU D CA  1 
ATOM   11611 C C   . LEU D 1 123 ? -5.951  10.001  -81.541  1.00 27.76  ? 116  LEU D C   1 
ATOM   11612 O O   . LEU D 1 123 ? -5.521  10.270  -82.701  1.00 32.47  ? 116  LEU D O   1 
ATOM   11613 C CB  . LEU D 1 123 ? -5.669  7.586   -80.915  1.00 26.36  ? 116  LEU D CB  1 
ATOM   11614 C CG  . LEU D 1 123 ? -6.285  6.236   -80.564  1.00 27.28  ? 116  LEU D CG  1 
ATOM   11615 C CD1 . LEU D 1 123 ? -5.226  5.300   -79.987  1.00 25.73  ? 116  LEU D CD1 1 
ATOM   11616 C CD2 . LEU D 1 123 ? -7.441  6.386   -79.588  1.00 27.41  ? 116  LEU D CD2 1 
ATOM   11617 N N   . HIS D 1 124 ? -5.819  10.763  -80.464  1.00 26.39  ? 117  HIS D N   1 
ATOM   11618 C CA  . HIS D 1 124 ? -5.288  12.147  -80.439  1.00 29.53  ? 117  HIS D CA  1 
ATOM   11619 C C   . HIS D 1 124 ? -3.789  12.135  -80.079  1.00 30.50  ? 117  HIS D C   1 
ATOM   11620 O O   . HIS D 1 124 ? -3.261  11.072  -79.658  1.00 29.08  ? 117  HIS D O   1 
ATOM   11621 C CB  . HIS D 1 124 ? -6.156  13.022  -79.514  1.00 29.35  ? 117  HIS D CB  1 
ATOM   11622 C CG  . HIS D 1 124 ? -6.132  12.588  -78.091  1.00 28.08  ? 117  HIS D CG  1 
ATOM   11623 N ND1 . HIS D 1 124 ? -6.555  11.334  -77.714  1.00 28.12  ? 117  HIS D ND1 1 
ATOM   11624 C CD2 . HIS D 1 124 ? -5.736  13.219  -76.963  1.00 30.02  ? 117  HIS D CD2 1 
ATOM   11625 C CE1 . HIS D 1 124 ? -6.417  11.196  -76.409  1.00 31.73  ? 117  HIS D CE1 1 
ATOM   11626 N NE2 . HIS D 1 124 ? -5.902  12.341  -75.914  1.00 30.44  ? 117  HIS D NE2 1 
ATOM   11627 N N   . SER D 1 125 ? -3.138  13.287  -80.276  1.00 32.75  ? 118  SER D N   1 
ATOM   11628 C CA  . SER D 1 125 ? -1.682  13.523  -80.081  1.00 34.85  ? 118  SER D CA  1 
ATOM   11629 C C   . SER D 1 125 ? -1.388  13.702  -78.591  1.00 36.70  ? 118  SER D C   1 
ATOM   11630 O O   . SER D 1 125 ? -0.279  13.341  -78.156  1.00 32.75  ? 118  SER D O   1 
ATOM   11631 C CB  . SER D 1 125 ? -1.230  14.743  -80.833  1.00 34.19  ? 118  SER D CB  1 
ATOM   11632 O OG  . SER D 1 125 ? -1.933  15.900  -80.381  1.00 35.78  ? 118  SER D OG  1 
ATOM   11633 N N   . GLN D 1 126 ? -2.356  14.268  -77.865  1.00 39.12  ? 119  GLN D N   1 
ATOM   11634 C CA  . GLN D 1 126 ? -2.246  14.709  -76.453  1.00 43.91  ? 119  GLN D CA  1 
ATOM   11635 C C   . GLN D 1 126 ? -1.424  16.002  -76.358  1.00 44.60  ? 119  GLN D C   1 
ATOM   11636 O O   . GLN D 1 126 ? -1.021  16.344  -75.238  1.00 56.35  ? 119  GLN D O   1 
ATOM   11637 C CB  . GLN D 1 126 ? -1.614  13.619  -75.585  1.00 48.31  ? 119  GLN D CB  1 
ATOM   11638 C CG  . GLN D 1 126 ? -2.522  12.435  -75.317  1.00 48.43  ? 119  GLN D CG  1 
ATOM   11639 C CD  . GLN D 1 126 ? -1.723  11.157  -75.377  1.00 47.46  ? 119  GLN D CD  1 
ATOM   11640 O OE1 . GLN D 1 126 ? -1.803  10.427  -76.352  1.00 49.59  ? 119  GLN D OE1 1 
ATOM   11641 N NE2 . GLN D 1 126 ? -0.899  10.907  -74.374  1.00 46.22  ? 119  GLN D NE2 1 
ATOM   11642 N N   . GLU D 1 127 ? -1.201  16.722  -77.456  1.00 40.07  ? 120  GLU D N   1 
ATOM   11643 C CA  . GLU D 1 127 ? -0.532  18.046  -77.397  1.00 42.09  ? 120  GLU D CA  1 
ATOM   11644 C C   . GLU D 1 127 ? -1.450  19.111  -77.994  1.00 41.06  ? 120  GLU D C   1 
ATOM   11645 O O   . GLU D 1 127 ? -1.618  20.149  -77.369  1.00 44.49  ? 120  GLU D O   1 
ATOM   11646 C CB  . GLU D 1 127 ? 0.817   18.021  -78.119  1.00 45.09  ? 120  GLU D CB  1 
ATOM   11647 C CG  . GLU D 1 127 ? 1.700   19.222  -77.814  1.00 43.92  ? 120  GLU D CG  1 
ATOM   11648 C CD  . GLU D 1 127 ? 2.257   19.287  -76.395  1.00 46.45  ? 120  GLU D CD  1 
ATOM   11649 O OE1 . GLU D 1 127 ? 2.186   18.259  -75.659  1.00 40.71  ? 120  GLU D OE1 1 
ATOM   11650 O OE2 . GLU D 1 127 ? 2.739   20.380  -76.015  1.00 53.02  ? 120  GLU D OE2 1 
ATOM   11651 N N   . LEU D 1 128 ? -1.996  18.890  -79.183  1.00 43.78  ? 121  LEU D N   1 
ATOM   11652 C CA  . LEU D 1 128 ? -3.015  19.807  -79.764  1.00 46.96  ? 121  LEU D CA  1 
ATOM   11653 C C   . LEU D 1 128 ? -4.320  19.647  -78.977  1.00 45.57  ? 121  LEU D C   1 
ATOM   11654 O O   . LEU D 1 128 ? -4.598  18.532  -78.494  1.00 45.81  ? 121  LEU D O   1 
ATOM   11655 C CB  . LEU D 1 128 ? -3.224  19.519  -81.253  1.00 50.06  ? 121  LEU D CB  1 
ATOM   11656 C CG  . LEU D 1 128 ? -2.252  20.246  -82.186  1.00 51.90  ? 121  LEU D CG  1 
ATOM   11657 C CD1 . LEU D 1 128 ? -0.829  19.782  -81.954  1.00 50.74  ? 121  LEU D CD1 1 
ATOM   11658 C CD2 . LEU D 1 128 ? -2.627  20.048  -83.649  1.00 53.78  ? 121  LEU D CD2 1 
ATOM   11659 N N   . LEU D 1 129 ? -5.076  20.738  -78.842  1.00 40.32  ? 122  LEU D N   1 
ATOM   11660 C CA  . LEU D 1 129 ? -6.427  20.732  -78.242  1.00 35.35  ? 122  LEU D CA  1 
ATOM   11661 C C   . LEU D 1 129 ? -7.272  19.766  -79.066  1.00 33.49  ? 122  LEU D C   1 
ATOM   11662 O O   . LEU D 1 129 ? -7.359  19.981  -80.254  1.00 34.75  ? 122  LEU D O   1 
ATOM   11663 C CB  . LEU D 1 129 ? -7.010  22.149  -78.275  1.00 34.67  ? 122  LEU D CB  1 
ATOM   11664 C CG  . LEU D 1 129 ? -6.182  23.254  -77.613  1.00 34.22  ? 122  LEU D CG  1 
ATOM   11665 C CD1 . LEU D 1 129 ? -6.918  24.585  -77.660  1.00 34.41  ? 122  LEU D CD1 1 
ATOM   11666 C CD2 . LEU D 1 129 ? -5.833  22.903  -76.173  1.00 34.97  ? 122  LEU D CD2 1 
ATOM   11667 N N   . ASP D 1 130 ? -7.824  18.715  -78.469  1.00 34.24  ? 123  ASP D N   1 
ATOM   11668 C CA  . ASP D 1 130 ? -8.746  17.792  -79.183  1.00 35.24  ? 123  ASP D CA  1 
ATOM   11669 C C   . ASP D 1 130 ? -10.178 18.275  -78.957  1.00 34.24  ? 123  ASP D C   1 
ATOM   11670 O O   . ASP D 1 130 ? -10.656 18.350  -77.833  1.00 36.06  ? 123  ASP D O   1 
ATOM   11671 C CB  . ASP D 1 130 ? -8.508  16.323  -78.826  1.00 35.76  ? 123  ASP D CB  1 
ATOM   11672 C CG  . ASP D 1 130 ? -8.399  16.025  -77.343  1.00 37.38  ? 123  ASP D CG  1 
ATOM   11673 O OD1 . ASP D 1 130 ? -7.870  16.887  -76.575  1.00 35.34  ? 123  ASP D OD1 1 
ATOM   11674 O OD2 . ASP D 1 130 ? -8.827  14.923  -76.964  1.00 38.03  ? 123  ASP D OD2 1 
ATOM   11675 N N   . PRO D 1 131 ? -10.914 18.594  -80.041  1.00 34.53  ? 124  PRO D N   1 
ATOM   11676 C CA  . PRO D 1 131 ? -12.182 19.308  -79.932  1.00 34.52  ? 124  PRO D CA  1 
ATOM   11677 C C   . PRO D 1 131 ? -13.360 18.484  -79.385  1.00 34.39  ? 124  PRO D C   1 
ATOM   11678 O O   . PRO D 1 131 ? -14.217 19.083  -78.770  1.00 35.04  ? 124  PRO D O   1 
ATOM   11679 C CB  . PRO D 1 131 ? -12.454 19.719  -81.384  1.00 36.29  ? 124  PRO D CB  1 
ATOM   11680 C CG  . PRO D 1 131 ? -11.825 18.608  -82.202  1.00 35.93  ? 124  PRO D CG  1 
ATOM   11681 C CD  . PRO D 1 131 ? -10.572 18.247  -81.430  1.00 36.48  ? 124  PRO D CD  1 
ATOM   11682 N N   . LEU D 1 132 ? -13.391 17.163  -79.601  1.00 32.45  ? 125  LEU D N   1 
ATOM   11683 C CA  . LEU D 1 132 ? -14.488 16.309  -79.066  1.00 31.80  ? 125  LEU D CA  1 
ATOM   11684 C C   . LEU D 1 132 ? -14.410 16.250  -77.533  1.00 32.98  ? 125  LEU D C   1 
ATOM   11685 O O   . LEU D 1 132 ? -15.467 16.114  -76.918  1.00 35.26  ? 125  LEU D O   1 
ATOM   11686 C CB  . LEU D 1 132 ? -14.419 14.901  -79.651  1.00 30.67  ? 125  LEU D CB  1 
ATOM   11687 C CG  . LEU D 1 132 ? -14.613 14.817  -81.160  1.00 33.34  ? 125  LEU D CG  1 
ATOM   11688 C CD1 . LEU D 1 132 ? -14.900 13.389  -81.574  1.00 33.42  ? 125  LEU D CD1 1 
ATOM   11689 C CD2 . LEU D 1 132 ? -15.731 15.729  -81.640  1.00 34.23  ? 125  LEU D CD2 1 
ATOM   11690 N N   . ARG D 1 133 ? -13.207 16.302  -76.949  1.00 31.83  ? 126  ARG D N   1 
ATOM   11691 C CA  . ARG D 1 133 ? -13.011 16.361  -75.483  1.00 31.28  ? 126  ARG D CA  1 
ATOM   11692 C C   . ARG D 1 133 ? -13.788 17.567  -74.952  1.00 30.81  ? 126  ARG D C   1 
ATOM   11693 O O   . ARG D 1 133 ? -14.660 17.374  -74.083  1.00 32.91  ? 126  ARG D O   1 
ATOM   11694 C CB  . ARG D 1 133 ? -11.526 16.462  -75.133  1.00 31.04  ? 126  ARG D CB  1 
ATOM   11695 C CG  . ARG D 1 133 ? -11.246 16.556  -73.635  1.00 31.20  ? 126  ARG D CG  1 
ATOM   11696 C CD  . ARG D 1 133 ? -9.763  16.774  -73.316  1.00 31.90  ? 126  ARG D CD  1 
ATOM   11697 N NE  . ARG D 1 133 ? -8.955  15.796  -74.024  1.00 31.30  ? 126  ARG D NE  1 
ATOM   11698 C CZ  . ARG D 1 133 ? -8.676  14.571  -73.594  1.00 33.16  ? 126  ARG D CZ  1 
ATOM   11699 N NH1 . ARG D 1 133 ? -9.069  14.147  -72.403  1.00 33.74  ? 126  ARG D NH1 1 
ATOM   11700 N NH2 . ARG D 1 133 ? -7.979  13.768  -74.371  1.00 35.48  ? 126  ARG D NH2 1 
ATOM   11701 N N   . ALA D 1 134 ? -13.494 18.749  -75.494  1.00 28.97  ? 127  ALA D N   1 
ATOM   11702 C CA  . ALA D 1 134 ? -14.152 20.035  -75.162  1.00 29.49  ? 127  ALA D CA  1 
ATOM   11703 C C   . ALA D 1 134 ? -15.679 19.925  -75.318  1.00 28.35  ? 127  ALA D C   1 
ATOM   11704 O O   . ALA D 1 134 ? -16.412 20.375  -74.415  1.00 26.28  ? 127  ALA D O   1 
ATOM   11705 C CB  . ALA D 1 134 ? -13.587 21.114  -76.042  1.00 29.67  ? 127  ALA D CB  1 
ATOM   11706 N N   . MET D 1 135 ? -16.138 19.338  -76.421  1.00 29.43  ? 128  MET D N   1 
ATOM   11707 C CA  . MET D 1 135 ? -17.585 19.191  -76.738  1.00 30.91  ? 128  MET D CA  1 
ATOM   11708 C C   . MET D 1 135 ? -18.241 18.233  -75.740  1.00 30.61  ? 128  MET D C   1 
ATOM   11709 O O   . MET D 1 135 ? -19.338 18.570  -75.233  1.00 33.59  ? 128  MET D O   1 
ATOM   11710 C CB  . MET D 1 135 ? -17.798 18.676  -78.165  1.00 35.54  ? 128  MET D CB  1 
ATOM   11711 C CG  . MET D 1 135 ? -17.362 19.678  -79.251  1.00 39.43  ? 128  MET D CG  1 
ATOM   11712 S SD  . MET D 1 135 ? -18.397 21.188  -79.263  1.00 45.83  ? 128  MET D SD  1 
ATOM   11713 C CE  . MET D 1 135 ? -17.275 22.382  -79.993  1.00 47.83  ? 128  MET D CE  1 
ATOM   11714 N N   . LEU D 1 136 ? -17.615 17.094  -75.438  1.00 27.60  ? 129  LEU D N   1 
ATOM   11715 C CA  . LEU D 1 136 ? -18.240 16.094  -74.539  1.00 25.73  ? 129  LEU D CA  1 
ATOM   11716 C C   . LEU D 1 136 ? -18.259 16.654  -73.119  1.00 26.22  ? 129  LEU D C   1 
ATOM   11717 O O   . LEU D 1 136 ? -19.234 16.397  -72.390  1.00 27.06  ? 129  LEU D O   1 
ATOM   11718 C CB  . LEU D 1 136 ? -17.488 14.770  -74.605  1.00 23.23  ? 129  LEU D CB  1 
ATOM   11719 C CG  . LEU D 1 136 ? -17.961 13.725  -73.596  1.00 22.61  ? 129  LEU D CG  1 
ATOM   11720 C CD1 . LEU D 1 136 ? -19.427 13.345  -73.810  1.00 21.76  ? 129  LEU D CD1 1 
ATOM   11721 C CD2 . LEU D 1 136 ? -17.070 12.494  -73.646  1.00 22.22  ? 129  LEU D CD2 1 
ATOM   11722 N N   . ALA D 1 137 ? -17.222 17.395  -72.742  1.00 27.68  ? 130  ALA D N   1 
ATOM   11723 C CA  . ALA D 1 137 ? -17.115 18.015  -71.402  1.00 26.75  ? 130  ALA D CA  1 
ATOM   11724 C C   . ALA D 1 137 ? -18.229 19.052  -71.248  1.00 28.29  ? 130  ALA D C   1 
ATOM   11725 O O   . ALA D 1 137 ? -18.873 19.071  -70.192  1.00 30.51  ? 130  ALA D O   1 
ATOM   11726 C CB  . ALA D 1 137 ? -15.749 18.618  -71.193  1.00 25.42  ? 130  ALA D CB  1 
ATOM   11727 N N   . LYS D 1 138 ? -18.440 19.883  -72.266  1.00 32.19  ? 131  LYS D N   1 
ATOM   11728 C CA  . LYS D 1 138 ? -19.513 20.906  -72.271  1.00 34.99  ? 131  LYS D CA  1 
ATOM   11729 C C   . LYS D 1 138 ? -20.860 20.196  -72.131  1.00 33.06  ? 131  LYS D C   1 
ATOM   11730 O O   . LYS D 1 138 ? -21.694 20.607  -71.296  1.00 34.16  ? 131  LYS D O   1 
ATOM   11731 C CB  . LYS D 1 138 ? -19.461 21.711  -73.572  1.00 39.79  ? 131  LYS D CB  1 
ATOM   11732 C CG  . LYS D 1 138 ? -20.615 22.683  -73.780  1.00 44.63  ? 131  LYS D CG  1 
ATOM   11733 C CD  . LYS D 1 138 ? -20.693 23.758  -72.710  1.00 48.66  ? 131  LYS D CD  1 
ATOM   11734 C CE  . LYS D 1 138 ? -21.848 24.710  -72.900  1.00 52.12  ? 131  LYS D CE  1 
ATOM   11735 N NZ  . LYS D 1 138 ? -22.243 25.290  -71.595  1.00 61.94  ? 131  LYS D NZ  1 
ATOM   11736 N N   . THR D 1 139 ? -21.047 19.160  -72.943  1.00 31.07  ? 132  THR D N   1 
ATOM   11737 C CA  . THR D 1 139 ? -22.269 18.324  -72.969  1.00 29.37  ? 132  THR D CA  1 
ATOM   11738 C C   . THR D 1 139 ? -22.501 17.742  -71.574  1.00 28.70  ? 132  THR D C   1 
ATOM   11739 O O   . THR D 1 139 ? -23.604 17.934  -71.027  1.00 27.95  ? 132  THR D O   1 
ATOM   11740 C CB  . THR D 1 139 ? -22.170 17.266  -74.077  1.00 30.60  ? 132  THR D CB  1 
ATOM   11741 O OG1 . THR D 1 139 ? -21.961 17.957  -75.311  1.00 29.21  ? 132  THR D OG1 1 
ATOM   11742 C CG2 . THR D 1 139 ? -23.396 16.386  -74.202  1.00 31.06  ? 132  THR D CG2 1 
ATOM   11743 N N   . LEU D 1 140 ? -21.497 17.084  -71.001  1.00 27.90  ? 133  LEU D N   1 
ATOM   11744 C CA  . LEU D 1 140 ? -21.665 16.424  -69.681  1.00 28.00  ? 133  LEU D CA  1 
ATOM   11745 C C   . LEU D 1 140 ? -21.950 17.464  -68.590  1.00 27.38  ? 133  LEU D C   1 
ATOM   11746 O O   . LEU D 1 140 ? -22.736 17.144  -67.683  1.00 26.14  ? 133  LEU D O   1 
ATOM   11747 C CB  . LEU D 1 140 ? -20.433 15.576  -69.370  1.00 28.16  ? 133  LEU D CB  1 
ATOM   11748 C CG  . LEU D 1 140 ? -20.436 14.192  -70.014  1.00 28.94  ? 133  LEU D CG  1 
ATOM   11749 C CD1 . LEU D 1 140 ? -19.152 13.449  -69.684  1.00 29.08  ? 133  LEU D CD1 1 
ATOM   11750 C CD2 . LEU D 1 140 ? -21.656 13.389  -69.569  1.00 28.99  ? 133  LEU D CD2 1 
ATOM   11751 N N   . ALA D 1 141 ? -21.390 18.672  -68.689  1.00 26.79  ? 134  ALA D N   1 
ATOM   11752 C CA  . ALA D 1 141 ? -21.668 19.772  -67.733  1.00 26.85  ? 134  ALA D CA  1 
ATOM   11753 C C   . ALA D 1 141 ? -23.158 20.157  -67.785  1.00 27.27  ? 134  ALA D C   1 
ATOM   11754 O O   . ALA D 1 141 ? -23.791 20.261  -66.727  1.00 30.33  ? 134  ALA D O   1 
ATOM   11755 C CB  . ALA D 1 141 ? -20.777 20.949  -68.028  1.00 26.37  ? 134  ALA D CB  1 
ATOM   11756 N N   . ALA D 1 142 ? -23.708 20.334  -68.984  1.00 29.40  ? 135  ALA D N   1 
ATOM   11757 C CA  . ALA D 1 142 ? -25.139 20.649  -69.214  1.00 29.07  ? 135  ALA D CA  1 
ATOM   11758 C C   . ALA D 1 142 ? -26.031 19.490  -68.744  1.00 27.66  ? 135  ALA D C   1 
ATOM   11759 O O   . ALA D 1 142 ? -27.118 19.762  -68.208  1.00 29.94  ? 135  ALA D O   1 
ATOM   11760 C CB  . ALA D 1 142 ? -25.362 20.960  -70.679  1.00 29.03  ? 135  ALA D CB  1 
ATOM   11761 N N   . LEU D 1 143 ? -25.599 18.247  -68.955  1.00 26.22  ? 136  LEU D N   1 
ATOM   11762 C CA  . LEU D 1 143 ? -26.407 17.038  -68.658  1.00 25.68  ? 136  LEU D CA  1 
ATOM   11763 C C   . LEU D 1 143 ? -26.434 16.785  -67.153  1.00 26.32  ? 136  LEU D C   1 
ATOM   11764 O O   . LEU D 1 143 ? -27.422 16.200  -66.681  1.00 25.87  ? 136  LEU D O   1 
ATOM   11765 C CB  . LEU D 1 143 ? -25.800 15.831  -69.371  1.00 26.43  ? 136  LEU D CB  1 
ATOM   11766 C CG  . LEU D 1 143 ? -26.591 14.528  -69.248  1.00 25.89  ? 136  LEU D CG  1 
ATOM   11767 C CD1 . LEU D 1 143 ? -27.958 14.696  -69.866  1.00 25.42  ? 136  LEU D CD1 1 
ATOM   11768 C CD2 . LEU D 1 143 ? -25.842 13.366  -69.896  1.00 26.38  ? 136  LEU D CD2 1 
ATOM   11769 N N   . THR D 1 144 ? -25.384 17.180  -66.428  1.00 28.40  ? 137  THR D N   1 
ATOM   11770 C CA  . THR D 1 144 ? -25.237 16.852  -64.990  1.00 29.77  ? 137  THR D CA  1 
ATOM   11771 C C   . THR D 1 144 ? -25.909 17.901  -64.116  1.00 32.13  ? 137  THR D C   1 
ATOM   11772 O O   . THR D 1 144 ? -26.017 19.071  -64.486  1.00 30.84  ? 137  THR D O   1 
ATOM   11773 C CB  . THR D 1 144 ? -23.780 16.723  -64.544  1.00 28.84  ? 137  THR D CB  1 
ATOM   11774 O OG1 . THR D 1 144 ? -23.094 17.908  -64.951  1.00 28.73  ? 137  THR D OG1 1 
ATOM   11775 C CG2 . THR D 1 144 ? -23.153 15.447  -65.063  1.00 30.17  ? 137  THR D CG2 1 
ATOM   11776 N N   . PRO D 1 145 ? -26.319 17.481  -62.898  1.00 34.71  ? 138  PRO D N   1 
ATOM   11777 C CA  . PRO D 1 145 ? -26.949 18.375  -61.934  1.00 39.31  ? 138  PRO D CA  1 
ATOM   11778 C C   . PRO D 1 145 ? -26.002 19.428  -61.348  1.00 40.18  ? 138  PRO D C   1 
ATOM   11779 O O   . PRO D 1 145 ? -24.833 19.146  -61.173  1.00 38.57  ? 138  PRO D O   1 
ATOM   11780 C CB  . PRO D 1 145 ? -27.449 17.446  -60.810  1.00 38.77  ? 138  PRO D CB  1 
ATOM   11781 C CG  . PRO D 1 145 ? -26.605 16.198  -60.933  1.00 37.80  ? 138  PRO D CG  1 
ATOM   11782 C CD  . PRO D 1 145 ? -26.249 16.097  -62.402  1.00 35.75  ? 138  PRO D CD  1 
ATOM   11783 N N   . GLY D 1 146 ? -26.562 20.616  -61.109  1.00 42.54  ? 139  GLY D N   1 
ATOM   11784 C CA  . GLY D 1 146 ? -26.005 21.691  -60.276  1.00 42.13  ? 139  GLY D CA  1 
ATOM   11785 C C   . GLY D 1 146 ? -24.624 22.112  -60.730  1.00 42.63  ? 139  GLY D C   1 
ATOM   11786 O O   . GLY D 1 146 ? -24.440 22.458  -61.928  1.00 42.60  ? 139  GLY D O   1 
ATOM   11787 N N   . LYS D 1 147 ? -23.682 22.058  -59.792  1.00 41.45  ? 140  LYS D N   1 
ATOM   11788 C CA  . LYS D 1 147 ? -22.367 22.723  -59.892  1.00 42.79  ? 140  LYS D CA  1 
ATOM   11789 C C   . LYS D 1 147 ? -21.324 21.739  -60.436  1.00 37.66  ? 140  LYS D C   1 
ATOM   11790 O O   . LYS D 1 147 ? -20.160 22.148  -60.522  1.00 34.37  ? 140  LYS D O   1 
ATOM   11791 C CB  . LYS D 1 147 ? -22.026 23.323  -58.527  1.00 48.24  ? 140  LYS D CB  1 
ATOM   11792 C CG  . LYS D 1 147 ? -22.974 24.449  -58.122  1.00 54.07  ? 140  LYS D CG  1 
ATOM   11793 C CD  . LYS D 1 147 ? -23.194 24.648  -56.611  1.00 66.19  ? 140  LYS D CD  1 
ATOM   11794 C CE  . LYS D 1 147 ? -22.003 25.172  -55.826  1.00 74.95  ? 140  LYS D CE  1 
ATOM   11795 N NZ  . LYS D 1 147 ? -21.588 26.516  -56.291  1.00 81.22  ? 140  LYS D NZ  1 
ATOM   11796 N N   . LEU D 1 148 ? -21.721 20.513  -60.797  1.00 33.56  ? 141  LEU D N   1 
ATOM   11797 C CA  . LEU D 1 148 ? -20.869 19.585  -61.588  1.00 33.04  ? 141  LEU D CA  1 
ATOM   11798 C C   . LEU D 1 148 ? -20.544 20.229  -62.942  1.00 31.98  ? 141  LEU D C   1 
ATOM   11799 O O   . LEU D 1 148 ? -21.474 20.460  -63.725  1.00 29.72  ? 141  LEU D O   1 
ATOM   11800 C CB  . LEU D 1 148 ? -21.564 18.235  -61.765  1.00 34.47  ? 141  LEU D CB  1 
ATOM   11801 C CG  . LEU D 1 148 ? -21.618 17.374  -60.512  1.00 36.75  ? 141  LEU D CG  1 
ATOM   11802 C CD1 . LEU D 1 148 ? -22.374 16.079  -60.783  1.00 38.78  ? 141  LEU D CD1 1 
ATOM   11803 C CD2 . LEU D 1 148 ? -20.228 17.075  -59.976  1.00 37.26  ? 141  LEU D CD2 1 
ATOM   11804 N N   . LYS D 1 149 ? -19.257 20.506  -63.194  1.00 32.88  ? 142  LYS D N   1 
ATOM   11805 C CA  . LYS D 1 149 ? -18.801 21.440  -64.257  1.00 31.48  ? 142  LYS D CA  1 
ATOM   11806 C C   . LYS D 1 149 ? -17.586 20.899  -65.019  1.00 29.23  ? 142  LYS D C   1 
ATOM   11807 O O   . LYS D 1 149 ? -17.504 21.165  -66.215  1.00 30.26  ? 142  LYS D O   1 
ATOM   11808 C CB  . LYS D 1 149 ? -18.500 22.808  -63.640  1.00 32.66  ? 142  LYS D CB  1 
ATOM   11809 C CG  . LYS D 1 149 ? -18.158 23.904  -64.644  1.00 36.13  ? 142  LYS D CG  1 
ATOM   11810 C CD  . LYS D 1 149 ? -18.251 25.314  -64.104  1.00 39.10  ? 142  LYS D CD  1 
ATOM   11811 C CE  . LYS D 1 149 ? -17.932 26.368  -65.150  1.00 42.03  ? 142  LYS D CE  1 
ATOM   11812 N NZ  . LYS D 1 149 ? -16.477 26.614  -65.263  1.00 41.53  ? 142  LYS D NZ  1 
ATOM   11813 N N   . TYR D 1 150 ? -16.642 20.230  -64.364  1.00 28.36  ? 143  TYR D N   1 
ATOM   11814 C CA  . TYR D 1 150 ? -15.379 19.808  -65.012  1.00 27.51  ? 143  TYR D CA  1 
ATOM   11815 C C   . TYR D 1 150 ? -15.395 18.296  -65.146  1.00 26.17  ? 143  TYR D C   1 
ATOM   11816 O O   . TYR D 1 150 ? -15.900 17.614  -64.262  1.00 26.86  ? 143  TYR D O   1 
ATOM   11817 C CB  . TYR D 1 150 ? -14.158 20.337  -64.266  1.00 28.31  ? 143  TYR D CB  1 
ATOM   11818 C CG  . TYR D 1 150 ? -13.877 21.784  -64.573  1.00 31.04  ? 143  TYR D CG  1 
ATOM   11819 C CD1 . TYR D 1 150 ? -14.488 22.793  -63.857  1.00 32.90  ? 143  TYR D CD1 1 
ATOM   11820 C CD2 . TYR D 1 150 ? -13.012 22.148  -65.589  1.00 31.93  ? 143  TYR D CD2 1 
ATOM   11821 C CE1 . TYR D 1 150 ? -14.258 24.129  -64.139  1.00 35.43  ? 143  TYR D CE1 1 
ATOM   11822 C CE2 . TYR D 1 150 ? -12.776 23.479  -65.895  1.00 33.71  ? 143  TYR D CE2 1 
ATOM   11823 C CZ  . TYR D 1 150 ? -13.399 24.477  -65.165  1.00 35.53  ? 143  TYR D CZ  1 
ATOM   11824 O OH  . TYR D 1 150 ? -13.191 25.800  -65.441  1.00 40.11  ? 143  TYR D OH  1 
ATOM   11825 N N   . SER D 1 151 ? -14.894 17.825  -66.284  1.00 25.47  ? 144  SER D N   1 
ATOM   11826 C CA  . SER D 1 151 ? -14.834 16.396  -66.676  1.00 24.09  ? 144  SER D CA  1 
ATOM   11827 C C   . SER D 1 151 ? -13.382 16.004  -66.960  1.00 23.49  ? 144  SER D C   1 
ATOM   11828 O O   . SER D 1 151 ? -12.649 16.790  -67.576  1.00 24.51  ? 144  SER D O   1 
ATOM   11829 C CB  . SER D 1 151 ? -15.724 16.131  -67.848  1.00 22.68  ? 144  SER D CB  1 
ATOM   11830 O OG  . SER D 1 151 ? -17.048 16.526  -67.553  1.00 22.60  ? 144  SER D OG  1 
ATOM   11831 N N   . PHE D 1 152 ? -12.995 14.849  -66.437  1.00 24.06  ? 145  PHE D N   1 
ATOM   11832 C CA  . PHE D 1 152 ? -11.751 14.121  -66.742  1.00 24.06  ? 145  PHE D CA  1 
ATOM   11833 C C   . PHE D 1 152 ? -12.153 12.776  -67.343  1.00 25.14  ? 145  PHE D C   1 
ATOM   11834 O O   . PHE D 1 152 ? -12.924 12.058  -66.701  1.00 24.36  ? 145  PHE D O   1 
ATOM   11835 C CB  . PHE D 1 152 ? -10.922 13.903  -65.481  1.00 26.49  ? 145  PHE D CB  1 
ATOM   11836 C CG  . PHE D 1 152 ? -9.773  12.963  -65.726  1.00 27.97  ? 145  PHE D CG  1 
ATOM   11837 C CD1 . PHE D 1 152 ? -8.588  13.440  -66.258  1.00 28.34  ? 145  PHE D CD1 1 
ATOM   11838 C CD2 . PHE D 1 152 ? -9.916  11.601  -65.516  1.00 28.06  ? 145  PHE D CD2 1 
ATOM   11839 C CE1 . PHE D 1 152 ? -7.543  12.576  -66.520  1.00 30.27  ? 145  PHE D CE1 1 
ATOM   11840 C CE2 . PHE D 1 152 ? -8.870  10.738  -65.774  1.00 27.37  ? 145  PHE D CE2 1 
ATOM   11841 C CZ  . PHE D 1 152 ? -7.698  11.224  -66.292  1.00 30.14  ? 145  PHE D CZ  1 
ATOM   11842 N N   . PHE D 1 153 ? -11.641 12.456  -68.531  1.00 25.61  ? 146  PHE D N   1 
ATOM   11843 C CA  . PHE D 1 153 ? -11.995 11.240  -69.302  1.00 23.75  ? 146  PHE D CA  1 
ATOM   11844 C C   . PHE D 1 153 ? -10.883 10.206  -69.188  1.00 23.43  ? 146  PHE D C   1 
ATOM   11845 O O   . PHE D 1 153 ? -9.697  10.548  -69.269  1.00 23.85  ? 146  PHE D O   1 
ATOM   11846 C CB  . PHE D 1 153 ? -12.247 11.607  -70.756  1.00 25.67  ? 146  PHE D CB  1 
ATOM   11847 C CG  . PHE D 1 153 ? -13.344 12.621  -70.886  1.00 26.89  ? 146  PHE D CG  1 
ATOM   11848 C CD1 . PHE D 1 153 ? -14.641 12.282  -70.533  1.00 27.46  ? 146  PHE D CD1 1 
ATOM   11849 C CD2 . PHE D 1 153 ? -13.078 13.913  -71.320  1.00 27.56  ? 146  PHE D CD2 1 
ATOM   11850 C CE1 . PHE D 1 153 ? -15.655 13.217  -70.623  1.00 26.15  ? 146  PHE D CE1 1 
ATOM   11851 C CE2 . PHE D 1 153 ? -14.106 14.837  -71.435  1.00 28.99  ? 146  PHE D CE2 1 
ATOM   11852 C CZ  . PHE D 1 153 ? -15.386 14.494  -71.062  1.00 26.61  ? 146  PHE D CZ  1 
ATOM   11853 N N   . CYS D 1 154 ? -11.296 8.969   -68.967  1.00 21.76  ? 147  CYS D N   1 
ATOM   11854 C CA  . CYS D 1 154 ? -10.426 7.786   -68.824  1.00 21.64  ? 147  CYS D CA  1 
ATOM   11855 C C   . CYS D 1 154 ? -11.076 6.670   -69.630  1.00 20.62  ? 147  CYS D C   1 
ATOM   11856 O O   . CYS D 1 154 ? -11.930 7.002   -70.490  1.00 18.86  ? 147  CYS D O   1 
ATOM   11857 C CB  . CYS D 1 154 ? -10.241 7.445   -67.354  1.00 22.85  ? 147  CYS D CB  1 
ATOM   11858 S SG  . CYS D 1 154 ? -11.767 7.483   -66.380  1.00 25.00  ? 147  CYS D SG  1 
ATOM   11859 N N   . ASN D 1 155 ? -10.704 5.418   -69.372  1.00 20.45  ? 148  ASN D N   1 
ATOM   11860 C CA  . ASN D 1 155 ? -11.047 4.283   -70.257  1.00 21.59  ? 148  ASN D CA  1 
ATOM   11861 C C   . ASN D 1 155 ? -11.894 3.230   -69.534  1.00 22.00  ? 148  ASN D C   1 
ATOM   11862 O O   . ASN D 1 155 ? -12.273 2.265   -70.216  1.00 23.36  ? 148  ASN D O   1 
ATOM   11863 C CB  . ASN D 1 155 ? -9.787  3.649   -70.839  1.00 21.87  ? 148  ASN D CB  1 
ATOM   11864 C CG  . ASN D 1 155 ? -8.861  4.663   -71.478  1.00 21.80  ? 148  ASN D CG  1 
ATOM   11865 O OD1 . ASN D 1 155 ? -9.202  5.260   -72.503  1.00 19.71  ? 148  ASN D OD1 1 
ATOM   11866 N ND2 . ASN D 1 155 ? -7.696  4.870   -70.872  1.00 23.35  ? 148  ASN D ND2 1 
ATOM   11867 N N   . SER D 1 156 ? -12.207 3.380   -68.242  1.00 21.13  ? 149  SER D N   1 
ATOM   11868 C CA  . SER D 1 156 ? -12.965 2.339   -67.496  1.00 20.30  ? 149  SER D CA  1 
ATOM   11869 C C   . SER D 1 156 ? -13.626 2.895   -66.225  1.00 20.91  ? 149  SER D C   1 
ATOM   11870 O O   . SER D 1 156 ? -13.273 4.015   -65.797  1.00 21.08  ? 149  SER D O   1 
ATOM   11871 C CB  . SER D 1 156 ? -12.067 1.181   -67.187  1.00 19.07  ? 149  SER D CB  1 
ATOM   11872 O OG  . SER D 1 156 ? -11.036 1.587   -66.338  1.00 17.08  ? 149  SER D OG  1 
ATOM   11873 N N   . GLY D 1 157 ? -14.552 2.134   -65.643  1.00 19.67  ? 150  GLY D N   1 
ATOM   11874 C CA  . GLY D 1 157 ? -15.150 2.483   -64.347  1.00 20.27  ? 150  GLY D CA  1 
ATOM   11875 C C   . GLY D 1 157 ? -14.068 2.608   -63.282  1.00 20.84  ? 150  GLY D C   1 
ATOM   11876 O O   . GLY D 1 157 ? -14.013 3.637   -62.567  1.00 20.13  ? 150  GLY D O   1 
ATOM   11877 N N   . THR D 1 158 ? -13.187 1.616   -63.193  1.00 20.32  ? 151  THR D N   1 
ATOM   11878 C CA  . THR D 1 158 ? -12.126 1.576   -62.161  1.00 19.62  ? 151  THR D CA  1 
ATOM   11879 C C   . THR D 1 158 ? -11.234 2.812   -62.307  1.00 18.44  ? 151  THR D C   1 
ATOM   11880 O O   . THR D 1 158 ? -10.906 3.404   -61.274  1.00 20.24  ? 151  THR D O   1 
ATOM   11881 C CB  . THR D 1 158 ? -11.422 0.223   -62.184  1.00 18.31  ? 151  THR D CB  1 
ATOM   11882 O OG1 . THR D 1 158 ? -10.714 0.116   -60.962  1.00 19.97  ? 151  THR D OG1 1 
ATOM   11883 C CG2 . THR D 1 158 ? -10.478 0.054   -63.328  1.00 18.62  ? 151  THR D CG2 1 
ATOM   11884 N N   . GLU D 1 159 ? -10.934 3.246   -63.522  1.00 19.38  ? 152  GLU D N   1 
ATOM   11885 C CA  . GLU D 1 159 ? -10.101 4.457   -63.759  1.00 21.36  ? 152  GLU D CA  1 
ATOM   11886 C C   . GLU D 1 159 ? -10.880 5.694   -63.291  1.00 20.02  ? 152  GLU D C   1 
ATOM   11887 O O   . GLU D 1 159 ? -10.267 6.594   -62.721  1.00 20.45  ? 152  GLU D O   1 
ATOM   11888 C CB  . GLU D 1 159 ? -9.660  4.619   -65.216  1.00 23.18  ? 152  GLU D CB  1 
ATOM   11889 C CG  . GLU D 1 159 ? -8.409  3.844   -65.604  1.00 27.31  ? 152  GLU D CG  1 
ATOM   11890 C CD  . GLU D 1 159 ? -7.840  4.115   -67.007  1.00 29.86  ? 152  GLU D CD  1 
ATOM   11891 O OE1 . GLU D 1 159 ? -8.621  4.240   -67.945  1.00 29.63  ? 152  GLU D OE1 1 
ATOM   11892 O OE2 . GLU D 1 159 ? -6.596  4.242   -67.161  1.00 37.50  ? 152  GLU D OE2 1 
ATOM   11893 N N   A SER D 1 160 ? -12.186 5.745   -63.547  0.50 19.82  ? 153  SER D N   1 
ATOM   11894 N N   B SER D 1 160 ? -12.199 5.734   -63.496  0.50 20.15  ? 153  SER D N   1 
ATOM   11895 C CA  A SER D 1 160 ? -13.046 6.898   -63.175  0.50 19.73  ? 153  SER D CA  1 
ATOM   11896 C CA  B SER D 1 160 ? -13.049 6.904   -63.141  0.50 20.34  ? 153  SER D CA  1 
ATOM   11897 C C   A SER D 1 160 ? -13.091 7.020   -61.652  0.50 20.09  ? 153  SER D C   1 
ATOM   11898 C C   B SER D 1 160 ? -13.119 7.020   -61.623  0.50 20.41  ? 153  SER D C   1 
ATOM   11899 O O   A SER D 1 160 ? -13.083 8.164   -61.159  0.50 20.70  ? 153  SER D O   1 
ATOM   11900 O O   B SER D 1 160 ? -13.147 8.147   -61.097  0.50 20.87  ? 153  SER D O   1 
ATOM   11901 C CB  A SER D 1 160 ? -14.436 6.803   -63.766  0.50 20.24  ? 153  SER D CB  1 
ATOM   11902 C CB  B SER D 1 160 ? -14.434 6.842   -63.765  0.50 21.38  ? 153  SER D CB  1 
ATOM   11903 O OG  A SER D 1 160 ? -15.260 7.830   -63.237  0.50 19.68  ? 153  SER D OG  1 
ATOM   11904 O OG  B SER D 1 160 ? -15.262 5.867   -63.149  0.50 21.99  ? 153  SER D OG  1 
ATOM   11905 N N   . VAL D 1 161 ? -13.101 5.882   -60.943  1.00 19.89  ? 154  VAL D N   1 
ATOM   11906 C CA  . VAL D 1 161 ? -13.091 5.845   -59.456  1.00 20.34  ? 154  VAL D CA  1 
ATOM   11907 C C   . VAL D 1 161 ? -11.708 6.301   -58.969  1.00 20.54  ? 154  VAL D C   1 
ATOM   11908 O O   . VAL D 1 161 ? -11.648 7.137   -58.031  1.00 19.57  ? 154  VAL D O   1 
ATOM   11909 C CB  . VAL D 1 161 ? -13.501 4.451   -58.935  1.00 20.11  ? 154  VAL D CB  1 
ATOM   11910 C CG1 . VAL D 1 161 ? -13.108 4.225   -57.487  1.00 19.42  ? 154  VAL D CG1 1 
ATOM   11911 C CG2 . VAL D 1 161 ? -14.988 4.226   -59.096  1.00 19.32  ? 154  VAL D CG2 1 
ATOM   11912 N N   . GLU D 1 162 ? -10.631 5.820   -59.592  1.00 22.53  ? 155  GLU D N   1 
ATOM   11913 C CA  . GLU D 1 162 ? -9.249  6.238   -59.215  1.00 22.19  ? 155  GLU D CA  1 
ATOM   11914 C C   . GLU D 1 162 ? -9.161  7.761   -59.299  1.00 19.93  ? 155  GLU D C   1 
ATOM   11915 O O   . GLU D 1 162 ? -8.687  8.380   -58.360  1.00 20.18  ? 155  GLU D O   1 
ATOM   11916 C CB  . GLU D 1 162 ? -8.197  5.629   -60.140  1.00 25.60  ? 155  GLU D CB  1 
ATOM   11917 C CG  . GLU D 1 162 ? -8.087  4.123   -60.030  1.00 27.95  ? 155  GLU D CG  1 
ATOM   11918 C CD  . GLU D 1 162 ? -7.272  3.610   -58.859  1.00 30.76  ? 155  GLU D CD  1 
ATOM   11919 O OE1 . GLU D 1 162 ? -6.513  4.431   -58.238  1.00 33.89  ? 155  GLU D OE1 1 
ATOM   11920 O OE2 . GLU D 1 162 ? -7.407  2.395   -58.557  1.00 32.36  ? 155  GLU D OE2 1 
ATOM   11921 N N   . ALA D 1 163 ? -9.657  8.337   -60.389  1.00 19.27  ? 156  ALA D N   1 
ATOM   11922 C CA  . ALA D 1 163 ? -9.649  9.796   -60.630  1.00 19.25  ? 156  ALA D CA  1 
ATOM   11923 C C   . ALA D 1 163 ? -10.416 10.512  -59.510  1.00 19.12  ? 156  ALA D C   1 
ATOM   11924 O O   . ALA D 1 163 ? -9.946  11.557  -59.036  1.00 17.52  ? 156  ALA D O   1 
ATOM   11925 C CB  . ALA D 1 163 ? -10.218 10.087  -61.996  1.00 18.99  ? 156  ALA D CB  1 
ATOM   11926 N N   . ALA D 1 164 ? -11.558 9.958   -59.097  1.00 20.49  ? 157  ALA D N   1 
ATOM   11927 C CA  . ALA D 1 164 ? -12.413 10.537  -58.043  1.00 20.47  ? 157  ALA D CA  1 
ATOM   11928 C C   . ALA D 1 164 ? -11.638 10.540  -56.721  1.00 22.66  ? 157  ALA D C   1 
ATOM   11929 O O   . ALA D 1 164 ? -11.486 11.613  -56.084  1.00 23.74  ? 157  ALA D O   1 
ATOM   11930 C CB  . ALA D 1 164 ? -13.693 9.745   -57.951  1.00 20.06  ? 157  ALA D CB  1 
ATOM   11931 N N   . LEU D 1 165 ? -11.152 9.366   -56.323  1.00 22.72  ? 158  LEU D N   1 
ATOM   11932 C CA  . LEU D 1 165 ? -10.336 9.198   -55.096  1.00 21.31  ? 158  LEU D CA  1 
ATOM   11933 C C   . LEU D 1 165 ? -9.208  10.223  -55.153  1.00 20.56  ? 158  LEU D C   1 
ATOM   11934 O O   . LEU D 1 165 ? -8.938  10.844  -54.130  1.00 20.71  ? 158  LEU D O   1 
ATOM   11935 C CB  . LEU D 1 165 ? -9.780  7.770   -55.029  1.00 22.57  ? 158  LEU D CB  1 
ATOM   11936 C CG  . LEU D 1 165 ? -10.813 6.661   -54.834  1.00 22.94  ? 158  LEU D CG  1 
ATOM   11937 C CD1 . LEU D 1 165 ? -10.170 5.284   -54.909  1.00 24.02  ? 158  LEU D CD1 1 
ATOM   11938 C CD2 . LEU D 1 165 ? -11.553 6.834   -53.526  1.00 22.93  ? 158  LEU D CD2 1 
ATOM   11939 N N   . LYS D 1 166 ? -8.596  10.415  -56.321  1.00 19.58  ? 159  LYS D N   1 
ATOM   11940 C CA  . LYS D 1 166 ? -7.426  11.316  -56.462  1.00 20.27  ? 159  LYS D CA  1 
ATOM   11941 C C   . LYS D 1 166 ? -7.878  12.770  -56.304  1.00 20.26  ? 159  LYS D C   1 
ATOM   11942 O O   . LYS D 1 166 ? -7.223  13.511  -55.544  1.00 19.04  ? 159  LYS D O   1 
ATOM   11943 C CB  . LYS D 1 166 ? -6.665  11.027  -57.756  1.00 20.51  ? 159  LYS D CB  1 
ATOM   11944 C CG  . LYS D 1 166 ? -5.766  9.792   -57.696  1.00 20.55  ? 159  LYS D CG  1 
ATOM   11945 C CD  . LYS D 1 166 ? -4.864  9.572   -58.904  1.00 21.03  ? 159  LYS D CD  1 
ATOM   11946 C CE  . LYS D 1 166 ? -3.730  10.579  -59.018  1.00 20.58  ? 159  LYS D CE  1 
ATOM   11947 N NZ  . LYS D 1 166 ? -2.910  10.396  -60.252  1.00 19.45  ? 159  LYS D NZ  1 
ATOM   11948 N N   . LEU D 1 167 ? -8.984  13.159  -56.927  1.00 21.50  ? 160  LEU D N   1 
ATOM   11949 C CA  . LEU D 1 167 ? -9.534  14.531  -56.747  1.00 22.97  ? 160  LEU D CA  1 
ATOM   11950 C C   . LEU D 1 167 ? -9.764  14.776  -55.255  1.00 23.43  ? 160  LEU D C   1 
ATOM   11951 O O   . LEU D 1 167 ? -9.298  15.806  -54.735  1.00 25.70  ? 160  LEU D O   1 
ATOM   11952 C CB  . LEU D 1 167 ? -10.823 14.686  -57.556  1.00 24.42  ? 160  LEU D CB  1 
ATOM   11953 C CG  . LEU D 1 167 ? -10.634 14.796  -59.068  1.00 23.76  ? 160  LEU D CG  1 
ATOM   11954 C CD1 . LEU D 1 167 ? -11.966 14.734  -59.761  1.00 25.67  ? 160  LEU D CD1 1 
ATOM   11955 C CD2 . LEU D 1 167 ? -9.919  16.082  -59.442  1.00 23.61  ? 160  LEU D CD2 1 
ATOM   11956 N N   . ALA D 1 168 ? -10.374 13.819  -54.569  1.00 22.39  ? 161  ALA D N   1 
ATOM   11957 C CA  . ALA D 1 168 ? -10.702 13.947  -53.132  1.00 22.89  ? 161  ALA D CA  1 
ATOM   11958 C C   . ALA D 1 168 ? -9.406  14.096  -52.323  1.00 22.67  ? 161  ALA D C   1 
ATOM   11959 O O   . ALA D 1 168 ? -9.321  15.005  -51.453  1.00 21.10  ? 161  ALA D O   1 
ATOM   11960 C CB  . ALA D 1 168 ? -11.496 12.752  -52.680  1.00 24.03  ? 161  ALA D CB  1 
ATOM   11961 N N   . LYS D 1 169 ? -8.418  13.246  -52.611  1.00 20.96  ? 162  LYS D N   1 
ATOM   11962 C CA  . LYS D 1 169 ? -7.141  13.225  -51.878  1.00 19.18  ? 162  LYS D CA  1 
ATOM   11963 C C   . LYS D 1 169 ? -6.497  14.597  -52.028  1.00 19.72  ? 162  LYS D C   1 
ATOM   11964 O O   . LYS D 1 169 ? -6.055  15.141  -51.031  1.00 20.55  ? 162  LYS D O   1 
ATOM   11965 C CB  . LYS D 1 169 ? -6.252  12.093  -52.389  1.00 18.93  ? 162  LYS D CB  1 
ATOM   11966 C CG  . LYS D 1 169 ? -6.591  10.705  -51.867  1.00 18.59  ? 162  LYS D CG  1 
ATOM   11967 C CD  . LYS D 1 169 ? -5.619  9.642   -52.347  1.00 18.49  ? 162  LYS D CD  1 
ATOM   11968 C CE  . LYS D 1 169 ? -5.678  8.371   -51.522  1.00 18.52  ? 162  LYS D CE  1 
ATOM   11969 N NZ  . LYS D 1 169 ? -4.727  8.400   -50.390  1.00 18.45  ? 162  LYS D NZ  1 
ATOM   11970 N N   . ALA D 1 170 ? -6.467  15.147  -53.232  1.00 22.83  ? 163  ALA D N   1 
ATOM   11971 C CA  . ALA D 1 170 ? -5.749  16.407  -53.536  1.00 24.76  ? 163  ALA D CA  1 
ATOM   11972 C C   . ALA D 1 170 ? -6.498  17.562  -52.865  1.00 25.13  ? 163  ALA D C   1 
ATOM   11973 O O   . ALA D 1 170 ? -5.837  18.520  -52.403  1.00 24.98  ? 163  ALA D O   1 
ATOM   11974 C CB  . ALA D 1 170 ? -5.631  16.604  -55.040  1.00 24.76  ? 163  ALA D CB  1 
ATOM   11975 N N   . TYR D 1 171 ? -7.828  17.487  -52.819  1.00 25.01  ? 164  TYR D N   1 
ATOM   11976 C CA  . TYR D 1 171 ? -8.653  18.550  -52.204  1.00 26.26  ? 164  TYR D CA  1 
ATOM   11977 C C   . TYR D 1 171 ? -8.461  18.534  -50.688  1.00 25.41  ? 164  TYR D C   1 
ATOM   11978 O O   . TYR D 1 171 ? -8.314  19.609  -50.098  1.00 25.04  ? 164  TYR D O   1 
ATOM   11979 C CB  . TYR D 1 171 ? -10.133 18.369  -52.540  1.00 28.57  ? 164  TYR D CB  1 
ATOM   11980 C CG  . TYR D 1 171 ? -10.978 19.546  -52.133  1.00 29.89  ? 164  TYR D CG  1 
ATOM   11981 C CD1 . TYR D 1 171 ? -10.958 20.714  -52.874  1.00 30.42  ? 164  TYR D CD1 1 
ATOM   11982 C CD2 . TYR D 1 171 ? -11.764 19.516  -50.992  1.00 30.38  ? 164  TYR D CD2 1 
ATOM   11983 C CE1 . TYR D 1 171 ? -11.731 21.810  -52.515  1.00 32.83  ? 164  TYR D CE1 1 
ATOM   11984 C CE2 . TYR D 1 171 ? -12.537 20.605  -50.615  1.00 31.86  ? 164  TYR D CE2 1 
ATOM   11985 C CZ  . TYR D 1 171 ? -12.531 21.756  -51.384  1.00 32.23  ? 164  TYR D CZ  1 
ATOM   11986 O OH  . TYR D 1 171 ? -13.289 22.843  -51.042  1.00 30.02  ? 164  TYR D OH  1 
ATOM   11987 N N   . GLN D 1 172 ? -8.428  17.339  -50.095  1.00 24.55  ? 165  GLN D N   1 
ATOM   11988 C CA  . GLN D 1 172 ? -8.657  17.140  -48.642  1.00 25.25  ? 165  GLN D CA  1 
ATOM   11989 C C   . GLN D 1 172 ? -7.352  16.996  -47.841  1.00 24.97  ? 165  GLN D C   1 
ATOM   11990 O O   . GLN D 1 172 ? -7.388  17.338  -46.644  1.00 23.98  ? 165  GLN D O   1 
ATOM   11991 C CB  . GLN D 1 172 ? -9.579  15.938  -48.431  1.00 25.71  ? 165  GLN D CB  1 
ATOM   11992 C CG  . GLN D 1 172 ? -11.020 16.180  -48.869  1.00 25.85  ? 165  GLN D CG  1 
ATOM   11993 C CD  . GLN D 1 172 ? -11.803 17.112  -47.982  1.00 23.99  ? 165  GLN D CD  1 
ATOM   11994 O OE1 . GLN D 1 172 ? -11.420 18.251  -47.755  1.00 24.03  ? 165  GLN D OE1 1 
ATOM   11995 N NE2 . GLN D 1 172 ? -12.934 16.645  -47.492  1.00 23.06  ? 165  GLN D NE2 1 
ATOM   11996 N N   . SER D 1 173 ? -6.246  16.527  -48.429  1.00 27.29  ? 166  SER D N   1 
ATOM   11997 C CA  . SER D 1 173 ? -4.961  16.325  -47.704  1.00 27.58  ? 166  SER D CA  1 
ATOM   11998 C C   . SER D 1 173 ? -4.429  17.666  -47.201  1.00 26.22  ? 166  SER D C   1 
ATOM   11999 O O   . SER D 1 173 ? -4.076  17.768  -46.035  1.00 31.02  ? 166  SER D O   1 
ATOM   12000 C CB  . SER D 1 173 ? -3.960  15.550  -48.517  1.00 30.46  ? 166  SER D CB  1 
ATOM   12001 O OG  . SER D 1 173 ? -3.245  16.373  -49.422  1.00 38.59  ? 166  SER D OG  1 
ATOM   12002 N N   . PRO D 1 174 ? -4.481  18.769  -47.979  1.00 24.95  ? 167  PRO D N   1 
ATOM   12003 C CA  . PRO D 1 174 ? -4.101  20.082  -47.468  1.00 24.64  ? 167  PRO D CA  1 
ATOM   12004 C C   . PRO D 1 174 ? -5.083  20.582  -46.401  1.00 26.86  ? 167  PRO D C   1 
ATOM   12005 O O   . PRO D 1 174 ? -4.752  21.515  -45.708  1.00 28.63  ? 167  PRO D O   1 
ATOM   12006 C CB  . PRO D 1 174 ? -4.181  21.047  -48.660  1.00 25.41  ? 167  PRO D CB  1 
ATOM   12007 C CG  . PRO D 1 174 ? -4.523  20.192  -49.873  1.00 25.08  ? 167  PRO D CG  1 
ATOM   12008 C CD  . PRO D 1 174 ? -5.014  18.855  -49.347  1.00 25.94  ? 167  PRO D CD  1 
ATOM   12009 N N   . ARG D 1 175 ? -6.276  19.990  -46.329  1.00 27.92  ? 168  ARG D N   1 
ATOM   12010 C CA  . ARG D 1 175 ? -7.272  20.267  -45.267  1.00 29.71  ? 168  ARG D CA  1 
ATOM   12011 C C   . ARG D 1 175 ? -7.106  19.258  -44.113  1.00 30.65  ? 168  ARG D C   1 
ATOM   12012 O O   . ARG D 1 175 ? -7.904  19.333  -43.165  1.00 27.29  ? 168  ARG D O   1 
ATOM   12013 C CB  . ARG D 1 175 ? -8.676  20.278  -45.872  1.00 31.40  ? 168  ARG D CB  1 
ATOM   12014 C CG  . ARG D 1 175 ? -8.881  21.428  -46.846  1.00 34.16  ? 168  ARG D CG  1 
ATOM   12015 C CD  . ARG D 1 175 ? -10.181 21.327  -47.626  1.00 35.48  ? 168  ARG D CD  1 
ATOM   12016 N NE  . ARG D 1 175 ? -10.492 22.575  -48.299  1.00 35.50  ? 168  ARG D NE  1 
ATOM   12017 C CZ  . ARG D 1 175 ? -9.964  22.968  -49.442  1.00 39.12  ? 168  ARG D CZ  1 
ATOM   12018 N NH1 . ARG D 1 175 ? -9.088  22.209  -50.081  1.00 41.83  ? 168  ARG D NH1 1 
ATOM   12019 N NH2 . ARG D 1 175 ? -10.318 24.129  -49.956  1.00 43.81  ? 168  ARG D NH2 1 
ATOM   12020 N N   . GLY D 1 176 ? -6.108  18.365  -44.176  1.00 28.30  ? 169  GLY D N   1 
ATOM   12021 C CA  . GLY D 1 176 ? -5.785  17.429  -43.086  1.00 27.18  ? 169  GLY D CA  1 
ATOM   12022 C C   . GLY D 1 176 ? -6.738  16.249  -42.994  1.00 26.94  ? 169  GLY D C   1 
ATOM   12023 O O   . GLY D 1 176 ? -6.819  15.658  -41.910  1.00 27.56  ? 169  GLY D O   1 
ATOM   12024 N N   . LYS D 1 177 ? -7.415  15.878  -44.078  1.00 26.91  ? 170  LYS D N   1 
ATOM   12025 C CA  . LYS D 1 177 ? -8.368  14.735  -44.082  1.00 27.58  ? 170  LYS D CA  1 
ATOM   12026 C C   . LYS D 1 177 ? -7.887  13.675  -45.077  1.00 26.09  ? 170  LYS D C   1 
ATOM   12027 O O   . LYS D 1 177 ? -7.582  14.020  -46.231  1.00 24.53  ? 170  LYS D O   1 
ATOM   12028 C CB  . LYS D 1 177 ? -9.789  15.197  -44.414  1.00 26.91  ? 170  LYS D CB  1 
ATOM   12029 C CG  . LYS D 1 177 ? -10.353 16.262  -43.495  1.00 26.97  ? 170  LYS D CG  1 
ATOM   12030 C CD  . LYS D 1 177 ? -11.724 16.762  -43.900  1.00 25.60  ? 170  LYS D CD  1 
ATOM   12031 C CE  . LYS D 1 177 ? -12.206 17.906  -43.038  1.00 27.02  ? 170  LYS D CE  1 
ATOM   12032 N NZ  . LYS D 1 177 ? -13.657 18.151  -43.250  1.00 29.48  ? 170  LYS D NZ  1 
ATOM   12033 N N   . PHE D 1 178 ? -7.842  12.421  -44.635  1.00 26.92  ? 171  PHE D N   1 
ATOM   12034 C CA  . PHE D 1 178 ? -7.208  11.302  -45.377  1.00 28.19  ? 171  PHE D CA  1 
ATOM   12035 C C   . PHE D 1 178 ? -8.066  10.034  -45.336  1.00 29.08  ? 171  PHE D C   1 
ATOM   12036 O O   . PHE D 1 178 ? -7.791  9.129   -46.150  1.00 30.80  ? 171  PHE D O   1 
ATOM   12037 C CB  . PHE D 1 178 ? -5.817  11.014  -44.816  1.00 29.60  ? 171  PHE D CB  1 
ATOM   12038 C CG  . PHE D 1 178 ? -4.887  12.205  -44.817  1.00 30.75  ? 171  PHE D CG  1 
ATOM   12039 C CD1 . PHE D 1 178 ? -4.826  13.070  -43.730  1.00 32.21  ? 171  PHE D CD1 1 
ATOM   12040 C CD2 . PHE D 1 178 ? -4.086  12.469  -45.911  1.00 28.77  ? 171  PHE D CD2 1 
ATOM   12041 C CE1 . PHE D 1 178 ? -3.992  14.176  -43.746  1.00 30.72  ? 171  PHE D CE1 1 
ATOM   12042 C CE2 . PHE D 1 178 ? -3.222  13.549  -45.907  1.00 28.57  ? 171  PHE D CE2 1 
ATOM   12043 C CZ  . PHE D 1 178 ? -3.183  14.404  -44.831  1.00 28.97  ? 171  PHE D CZ  1 
ATOM   12044 N N   . THR D 1 179 ? -9.059  9.963   -44.449  1.00 27.69  ? 172  THR D N   1 
ATOM   12045 C CA  . THR D 1 179 ? -9.899  8.755   -44.309  1.00 26.75  ? 172  THR D CA  1 
ATOM   12046 C C   . THR D 1 179 ? -10.983 8.773   -45.409  1.00 24.97  ? 172  THR D C   1 
ATOM   12047 O O   . THR D 1 179 ? -11.498 9.856   -45.762  1.00 26.05  ? 172  THR D O   1 
ATOM   12048 C CB  . THR D 1 179 ? -10.415 8.627   -42.867  1.00 26.70  ? 172  THR D CB  1 
ATOM   12049 O OG1 . THR D 1 179 ? -9.297  8.440   -42.005  1.00 25.34  ? 172  THR D OG1 1 
ATOM   12050 C CG2 . THR D 1 179 ? -11.357 7.462   -42.675  1.00 27.34  ? 172  THR D CG2 1 
ATOM   12051 N N   . PHE D 1 180 ? -11.318 7.599   -45.940  1.00 21.79  ? 173  PHE D N   1 
ATOM   12052 C CA  . PHE D 1 180 ? -12.408 7.393   -46.925  1.00 21.08  ? 173  PHE D CA  1 
ATOM   12053 C C   . PHE D 1 180 ? -13.364 6.358   -46.359  1.00 20.15  ? 173  PHE D C   1 
ATOM   12054 O O   . PHE D 1 180 ? -12.874 5.362   -45.787  1.00 19.40  ? 173  PHE D O   1 
ATOM   12055 C CB  . PHE D 1 180 ? -11.859 6.889   -48.265  1.00 20.73  ? 173  PHE D CB  1 
ATOM   12056 C CG  . PHE D 1 180 ? -11.148 7.944   -49.057  1.00 19.75  ? 173  PHE D CG  1 
ATOM   12057 C CD1 . PHE D 1 180 ? -9.860  8.316   -48.744  1.00 20.62  ? 173  PHE D CD1 1 
ATOM   12058 C CD2 . PHE D 1 180 ? -11.790 8.587   -50.102  1.00 21.77  ? 173  PHE D CD2 1 
ATOM   12059 C CE1 . PHE D 1 180 ? -9.220  9.305   -49.476  1.00 22.20  ? 173  PHE D CE1 1 
ATOM   12060 C CE2 . PHE D 1 180 ? -11.146 9.560   -50.854  1.00 21.04  ? 173  PHE D CE2 1 
ATOM   12061 C CZ  . PHE D 1 180 ? -9.867  9.924   -50.535  1.00 22.00  ? 173  PHE D CZ  1 
ATOM   12062 N N   . ILE D 1 181 ? -14.669 6.595   -46.526  1.00 19.51  ? 174  ILE D N   1 
ATOM   12063 C CA  . ILE D 1 181 ? -15.735 5.639   -46.125  1.00 19.02  ? 174  ILE D CA  1 
ATOM   12064 C C   . ILE D 1 181 ? -16.384 5.095   -47.391  1.00 18.36  ? 174  ILE D C   1 
ATOM   12065 O O   . ILE D 1 181 ? -16.814 5.913   -48.252  1.00 18.55  ? 174  ILE D O   1 
ATOM   12066 C CB  . ILE D 1 181 ? -16.785 6.304   -45.215  1.00 20.70  ? 174  ILE D CB  1 
ATOM   12067 C CG1 . ILE D 1 181 ? -16.151 6.994   -44.015  1.00 23.03  ? 174  ILE D CG1 1 
ATOM   12068 C CG2 . ILE D 1 181 ? -17.852 5.309   -44.792  1.00 19.50  ? 174  ILE D CG2 1 
ATOM   12069 C CD1 . ILE D 1 181 ? -15.217 6.118   -43.214  1.00 25.58  ? 174  ILE D CD1 1 
ATOM   12070 N N   . ALA D 1 182 ? -16.476 3.768   -47.472  1.00 17.58  ? 175  ALA D N   1 
ATOM   12071 C CA  . ALA D 1 182 ? -17.277 3.053   -48.481  1.00 18.15  ? 175  ALA D CA  1 
ATOM   12072 C C   . ALA D 1 182 ? -18.298 2.201   -47.741  1.00 17.14  ? 175  ALA D C   1 
ATOM   12073 O O   . ALA D 1 182 ? -18.354 2.304   -46.501  1.00 19.18  ? 175  ALA D O   1 
ATOM   12074 C CB  . ALA D 1 182 ? -16.346 2.246   -49.353  1.00 18.55  ? 175  ALA D CB  1 
ATOM   12075 N N   . THR D 1 183 ? -19.079 1.411   -48.462  1.00 16.19  ? 176  THR D N   1 
ATOM   12076 C CA  . THR D 1 183 ? -20.139 0.562   -47.865  1.00 16.90  ? 176  THR D CA  1 
ATOM   12077 C C   . THR D 1 183 ? -19.817 -0.899  -48.167  1.00 17.10  ? 176  THR D C   1 
ATOM   12078 O O   . THR D 1 183 ? -19.245 -1.152  -49.193  1.00 15.78  ? 176  THR D O   1 
ATOM   12079 C CB  . THR D 1 183 ? -21.513 1.019   -48.369  1.00 16.94  ? 176  THR D CB  1 
ATOM   12080 O OG1 . THR D 1 183 ? -21.677 0.766   -49.768  1.00 16.20  ? 176  THR D OG1 1 
ATOM   12081 C CG2 . THR D 1 183 ? -21.708 2.502   -48.142  1.00 17.47  ? 176  THR D CG2 1 
ATOM   12082 N N   . SER D 1 184 ? -20.160 -1.816  -47.275  1.00 18.77  ? 177  SER D N   1 
ATOM   12083 C CA  . SER D 1 184 ? -20.070 -3.278  -47.517  1.00 19.58  ? 177  SER D CA  1 
ATOM   12084 C C   . SER D 1 184 ? -21.028 -3.626  -48.647  1.00 21.38  ? 177  SER D C   1 
ATOM   12085 O O   . SER D 1 184 ? -22.047 -2.902  -48.800  1.00 22.78  ? 177  SER D O   1 
ATOM   12086 C CB  . SER D 1 184 ? -20.399 -4.079  -46.280  1.00 20.46  ? 177  SER D CB  1 
ATOM   12087 O OG  . SER D 1 184 ? -21.607 -3.641  -45.679  1.00 17.24  ? 177  SER D OG  1 
ATOM   12088 N N   . GLY D 1 185 ? -20.689 -4.667  -49.417  1.00 22.80  ? 178  GLY D N   1 
ATOM   12089 C CA  . GLY D 1 185 ? -21.373 -5.050  -50.672  1.00 21.99  ? 178  GLY D CA  1 
ATOM   12090 C C   . GLY D 1 185 ? -20.988 -4.159  -51.848  1.00 20.49  ? 178  GLY D C   1 
ATOM   12091 O O   . GLY D 1 185 ? -21.370 -4.509  -52.970  1.00 19.40  ? 178  GLY D O   1 
ATOM   12092 N N   . ALA D 1 186 ? -20.256 -3.059  -51.608  1.00 19.50  ? 179  ALA D N   1 
ATOM   12093 C CA  . ALA D 1 186 ? -19.935 -2.020  -52.618  1.00 18.52  ? 179  ALA D CA  1 
ATOM   12094 C C   . ALA D 1 186 ? -18.923 -2.576  -53.636  1.00 17.89  ? 179  ALA D C   1 
ATOM   12095 O O   . ALA D 1 186 ? -18.064 -3.393  -53.266  1.00 17.57  ? 179  ALA D O   1 
ATOM   12096 C CB  . ALA D 1 186 ? -19.418 -0.758  -51.969  1.00 17.48  ? 179  ALA D CB  1 
ATOM   12097 N N   . PHE D 1 187 ? -19.079 -2.191  -54.898  1.00 16.57  ? 180  PHE D N   1 
ATOM   12098 C CA  . PHE D 1 187 ? -18.167 -2.566  -55.987  1.00 16.89  ? 180  PHE D CA  1 
ATOM   12099 C C   . PHE D 1 187 ? -17.800 -1.291  -56.739  1.00 16.90  ? 180  PHE D C   1 
ATOM   12100 O O   . PHE D 1 187 ? -18.708 -0.685  -57.315  1.00 16.42  ? 180  PHE D O   1 
ATOM   12101 C CB  . PHE D 1 187 ? -18.791 -3.616  -56.903  1.00 16.49  ? 180  PHE D CB  1 
ATOM   12102 C CG  . PHE D 1 187 ? -17.774 -4.122  -57.880  1.00 16.55  ? 180  PHE D CG  1 
ATOM   12103 C CD1 . PHE D 1 187 ? -16.820 -5.043  -57.478  1.00 17.62  ? 180  PHE D CD1 1 
ATOM   12104 C CD2 . PHE D 1 187 ? -17.661 -3.564  -59.142  1.00 16.63  ? 180  PHE D CD2 1 
ATOM   12105 C CE1 . PHE D 1 187 ? -15.827 -5.459  -58.362  1.00 18.34  ? 180  PHE D CE1 1 
ATOM   12106 C CE2 . PHE D 1 187 ? -16.660 -3.975  -60.022  1.00 17.03  ? 180  PHE D CE2 1 
ATOM   12107 C CZ  . PHE D 1 187 ? -15.754 -4.927  -59.636  1.00 16.99  ? 180  PHE D CZ  1 
ATOM   12108 N N   . HIS D 1 188 ? -16.520 -0.899  -56.698  1.00 16.27  ? 181  HIS D N   1 
ATOM   12109 C CA  . HIS D 1 188 ? -16.021 0.366   -57.304  1.00 15.67  ? 181  HIS D CA  1 
ATOM   12110 C C   . HIS D 1 188 ? -14.888 0.095   -58.306  1.00 14.79  ? 181  HIS D C   1 
ATOM   12111 O O   . HIS D 1 188 ? -14.248 1.073   -58.768  1.00 13.42  ? 181  HIS D O   1 
ATOM   12112 C CB  . HIS D 1 188 ? -15.624 1.336   -56.185  1.00 15.70  ? 181  HIS D CB  1 
ATOM   12113 C CG  . HIS D 1 188 ? -16.734 1.641   -55.257  1.00 15.89  ? 181  HIS D CG  1 
ATOM   12114 N ND1 . HIS D 1 188 ? -17.862 2.337   -55.673  1.00 17.04  ? 181  HIS D ND1 1 
ATOM   12115 C CD2 . HIS D 1 188 ? -16.907 1.344   -53.950  1.00 15.96  ? 181  HIS D CD2 1 
ATOM   12116 C CE1 . HIS D 1 188 ? -18.683 2.469   -54.646  1.00 16.09  ? 181  HIS D CE1 1 
ATOM   12117 N NE2 . HIS D 1 188 ? -18.127 1.848   -53.573  1.00 16.32  ? 181  HIS D NE2 1 
ATOM   12118 N N   . GLY D 1 189 ? -14.657 -1.177  -58.630  1.00 14.96  ? 182  GLY D N   1 
ATOM   12119 C CA  . GLY D 1 189 ? -13.558 -1.582  -59.523  1.00 16.74  ? 182  GLY D CA  1 
ATOM   12120 C C   . GLY D 1 189 ? -12.481 -2.400  -58.843  1.00 16.92  ? 182  GLY D C   1 
ATOM   12121 O O   . GLY D 1 189 ? -12.561 -2.630  -57.621  1.00 16.70  ? 182  GLY D O   1 
ATOM   12122 N N   . LYS D 1 190 ? -11.463 -2.757  -59.626  1.00 18.83  ? 183  LYS D N   1 
ATOM   12123 C CA  . LYS D 1 190 ? -10.464 -3.799  -59.288  1.00 19.42  ? 183  LYS D CA  1 
ATOM   12124 C C   . LYS D 1 190 ? -9.032  -3.269  -59.395  1.00 18.62  ? 183  LYS D C   1 
ATOM   12125 O O   . LYS D 1 190 ? -8.132  -3.987  -58.976  1.00 17.56  ? 183  LYS D O   1 
ATOM   12126 C CB  . LYS D 1 190 ? -10.736 -5.003  -60.190  1.00 20.76  ? 183  LYS D CB  1 
ATOM   12127 C CG  . LYS D 1 190 ? -12.081 -5.672  -59.944  1.00 21.97  ? 183  LYS D CG  1 
ATOM   12128 C CD  . LYS D 1 190 ? -11.887 -7.132  -59.590  1.00 23.44  ? 183  LYS D CD  1 
ATOM   12129 C CE  . LYS D 1 190 ? -13.167 -7.864  -59.247  1.00 25.31  ? 183  LYS D CE  1 
ATOM   12130 N NZ  . LYS D 1 190 ? -13.633 -8.757  -60.341  1.00 25.02  ? 183  LYS D NZ  1 
ATOM   12131 N N   . SER D 1 191 ? -8.823  -2.060  -59.910  1.00 20.05  ? 184  SER D N   1 
ATOM   12132 C CA  . SER D 1 191 ? -7.517  -1.369  -59.790  1.00 21.78  ? 184  SER D CA  1 
ATOM   12133 C C   . SER D 1 191 ? -7.305  -1.083  -58.310  1.00 20.50  ? 184  SER D C   1 
ATOM   12134 O O   . SER D 1 191 ? -8.305  -0.935  -57.606  1.00 21.46  ? 184  SER D O   1 
ATOM   12135 C CB  . SER D 1 191 ? -7.456  -0.120  -60.616  1.00 23.71  ? 184  SER D CB  1 
ATOM   12136 O OG  . SER D 1 191 ? -8.462  0.792   -60.222  1.00 23.59  ? 184  SER D OG  1 
ATOM   12137 N N   . LEU D 1 192 ? -6.064  -1.049  -57.854  1.00 19.61  ? 185  LEU D N   1 
ATOM   12138 C CA  . LEU D 1 192 ? -5.753  -1.131  -56.408  1.00 21.06  ? 185  LEU D CA  1 
ATOM   12139 C C   . LEU D 1 192 ? -6.310  0.077   -55.633  1.00 18.68  ? 185  LEU D C   1 
ATOM   12140 O O   . LEU D 1 192 ? -6.604  -0.094  -54.446  1.00 18.21  ? 185  LEU D O   1 
ATOM   12141 C CB  . LEU D 1 192 ? -4.239  -1.295  -56.233  1.00 23.37  ? 185  LEU D CB  1 
ATOM   12142 C CG  . LEU D 1 192 ? -3.708  -2.660  -56.682  1.00 24.57  ? 185  LEU D CG  1 
ATOM   12143 C CD1 . LEU D 1 192 ? -2.213  -2.633  -56.960  1.00 25.58  ? 185  LEU D CD1 1 
ATOM   12144 C CD2 . LEU D 1 192 ? -4.032  -3.729  -55.643  1.00 24.35  ? 185  LEU D CD2 1 
ATOM   12145 N N   . GLY D 1 193 ? -6.453  1.251   -56.244  1.00 16.67  ? 186  GLY D N   1 
ATOM   12146 C CA  . GLY D 1 193 ? -7.083  2.399   -55.568  1.00 15.85  ? 186  GLY D CA  1 
ATOM   12147 C C   . GLY D 1 193 ? -8.577  2.165   -55.410  1.00 15.48  ? 186  GLY D C   1 
ATOM   12148 O O   . GLY D 1 193 ? -9.130  2.319   -54.282  1.00 14.55  ? 186  GLY D O   1 
ATOM   12149 N N   . ALA D 1 194 ? -9.213  1.779   -56.505  1.00 14.84  ? 187  ALA D N   1 
ATOM   12150 C CA  . ALA D 1 194 ? -10.641 1.435   -56.567  1.00 15.13  ? 187  ALA D CA  1 
ATOM   12151 C C   . ALA D 1 194 ? -10.932 0.265   -55.630  1.00 14.32  ? 187  ALA D C   1 
ATOM   12152 O O   . ALA D 1 194 ? -11.948 0.330   -54.943  1.00 15.43  ? 187  ALA D O   1 
ATOM   12153 C CB  . ALA D 1 194 ? -11.031 1.122   -57.998  1.00 15.98  ? 187  ALA D CB  1 
ATOM   12154 N N   . LEU D 1 195 ? -10.076 -0.755  -55.599  1.00 13.05  ? 188  LEU D N   1 
ATOM   12155 C CA  . LEU D 1 195 ? -10.340 -2.014  -54.861  1.00 12.64  ? 188  LEU D CA  1 
ATOM   12156 C C   . LEU D 1 195 ? -10.277 -1.743  -53.356  1.00 13.25  ? 188  LEU D C   1 
ATOM   12157 O O   . LEU D 1 195 ? -10.857 -2.529  -52.589  1.00 12.38  ? 188  LEU D O   1 
ATOM   12158 C CB  . LEU D 1 195 ? -9.331  -3.069  -55.294  1.00 12.49  ? 188  LEU D CB  1 
ATOM   12159 C CG  . LEU D 1 195 ? -9.438  -4.418  -54.605  1.00 12.46  ? 188  LEU D CG  1 
ATOM   12160 C CD1 . LEU D 1 195 ? -10.749 -5.072  -54.946  1.00 12.39  ? 188  LEU D CD1 1 
ATOM   12161 C CD2 . LEU D 1 195 ? -8.282  -5.326  -55.012  1.00 12.18  ? 188  LEU D CD2 1 
ATOM   12162 N N   . SER D 1 196 ? -9.610  -0.663  -52.943  1.00 14.68  ? 189  SER D N   1 
ATOM   12163 C CA  . SER D 1 196 ? -9.581  -0.184  -51.529  1.00 15.47  ? 189  SER D CA  1 
ATOM   12164 C C   . SER D 1 196 ? -10.992 0.211   -51.069  1.00 14.87  ? 189  SER D C   1 
ATOM   12165 O O   . SER D 1 196 ? -11.265 0.102   -49.851  1.00 15.12  ? 189  SER D O   1 
ATOM   12166 C CB  . SER D 1 196 ? -8.609  0.945   -51.335  1.00 14.93  ? 189  SER D CB  1 
ATOM   12167 O OG  . SER D 1 196 ? -7.323  0.552   -51.774  1.00 15.71  ? 189  SER D OG  1 
ATOM   12168 N N   . ALA D 1 197 ? -11.842 0.652   -51.998  1.00 14.86  ? 190  ALA D N   1 
ATOM   12169 C CA  . ALA D 1 197 ? -13.262 1.008   -51.740  1.00 14.76  ? 190  ALA D CA  1 
ATOM   12170 C C   . ALA D 1 197 ? -14.173 -0.210  -51.982  1.00 14.54  ? 190  ALA D C   1 
ATOM   12171 O O   . ALA D 1 197 ? -15.104 -0.433  -51.179  1.00 15.34  ? 190  ALA D O   1 
ATOM   12172 C CB  . ALA D 1 197 ? -13.653 2.195   -52.586  1.00 14.36  ? 190  ALA D CB  1 
ATOM   12173 N N   . THR D 1 198 ? -13.918 -1.002  -53.020  1.00 14.64  ? 191  THR D N   1 
ATOM   12174 C CA  . THR D 1 198 ? -14.612 -2.293  -53.252  1.00 16.21  ? 191  THR D CA  1 
ATOM   12175 C C   . THR D 1 198 ? -14.602 -3.070  -51.932  1.00 17.09  ? 191  THR D C   1 
ATOM   12176 O O   . THR D 1 198 ? -13.631 -2.952  -51.188  1.00 18.98  ? 191  THR D O   1 
ATOM   12177 C CB  . THR D 1 198 ? -14.002 -3.027  -54.454  1.00 17.08  ? 191  THR D CB  1 
ATOM   12178 O OG1 . THR D 1 198 ? -14.284 -2.240  -55.614  1.00 17.55  ? 191  THR D OG1 1 
ATOM   12179 C CG2 . THR D 1 198 ? -14.530 -4.434  -54.636  1.00 17.63  ? 191  THR D CG2 1 
ATOM   12180 N N   . ALA D 1 199 ? -15.668 -3.795  -51.614  1.00 17.83  ? 192  ALA D N   1 
ATOM   12181 C CA  . ALA D 1 199 ? -15.895 -4.296  -50.251  1.00 18.76  ? 192  ALA D CA  1 
ATOM   12182 C C   . ALA D 1 199 ? -15.857 -5.820  -50.194  1.00 20.38  ? 192  ALA D C   1 
ATOM   12183 O O   . ALA D 1 199 ? -15.880 -6.326  -49.084  1.00 24.19  ? 192  ALA D O   1 
ATOM   12184 C CB  . ALA D 1 199 ? -17.200 -3.772  -49.718  1.00 20.05  ? 192  ALA D CB  1 
ATOM   12185 N N   . LYS D 1 200 ? -15.854 -6.552  -51.294  1.00 22.78  ? 193  LYS D N   1 
ATOM   12186 C CA  . LYS D 1 200 ? -15.951 -8.027  -51.170  1.00 25.77  ? 193  LYS D CA  1 
ATOM   12187 C C   . LYS D 1 200 ? -14.581 -8.557  -50.750  1.00 22.88  ? 193  LYS D C   1 
ATOM   12188 O O   . LYS D 1 200 ? -13.580 -8.178  -51.378  1.00 18.94  ? 193  LYS D O   1 
ATOM   12189 C CB  . LYS D 1 200 ? -16.484 -8.682  -52.450  1.00 33.34  ? 193  LYS D CB  1 
ATOM   12190 C CG  . LYS D 1 200 ? -16.302 -10.202 -52.552  1.00 41.05  ? 193  LYS D CG  1 
ATOM   12191 C CD  . LYS D 1 200 ? -17.543 -11.083 -52.384  1.00 45.94  ? 193  LYS D CD  1 
ATOM   12192 C CE  . LYS D 1 200 ? -17.837 -11.931 -53.604  1.00 51.07  ? 193  LYS D CE  1 
ATOM   12193 N NZ  . LYS D 1 200 ? -17.624 -11.187 -54.868  1.00 58.45  ? 193  LYS D NZ  1 
ATOM   12194 N N   . SER D 1 201 ? -14.574 -9.407  -49.719  1.00 23.91  ? 194  SER D N   1 
ATOM   12195 C CA  . SER D 1 201 ? -13.372 -10.012 -49.087  1.00 23.75  ? 194  SER D CA  1 
ATOM   12196 C C   . SER D 1 201 ? -12.511 -10.718 -50.134  1.00 24.00  ? 194  SER D C   1 
ATOM   12197 O O   . SER D 1 201 ? -11.309 -10.427 -50.218  1.00 24.09  ? 194  SER D O   1 
ATOM   12198 C CB  . SER D 1 201 ? -13.751 -10.981 -48.021  1.00 23.06  ? 194  SER D CB  1 
ATOM   12199 O OG  . SER D 1 201 ? -12.589 -11.610 -47.504  1.00 27.25  ? 194  SER D OG  1 
ATOM   12200 N N   . THR D 1 202 ? -13.116 -11.645 -50.872  1.00 24.66  ? 195  THR D N   1 
ATOM   12201 C CA  . THR D 1 202 ? -12.439 -12.545 -51.848  1.00 24.93  ? 195  THR D CA  1 
ATOM   12202 C C   . THR D 1 202 ? -11.744 -11.721 -52.939  1.00 22.68  ? 195  THR D C   1 
ATOM   12203 O O   . THR D 1 202 ? -10.797 -12.223 -53.524  1.00 21.74  ? 195  THR D O   1 
ATOM   12204 C CB  . THR D 1 202 ? -13.421 -13.545 -52.474  1.00 27.51  ? 195  THR D CB  1 
ATOM   12205 O OG1 . THR D 1 202 ? -14.309 -12.846 -53.351  1.00 31.54  ? 195  THR D OG1 1 
ATOM   12206 C CG2 . THR D 1 202 ? -14.246 -14.292 -51.443  1.00 29.06  ? 195  THR D CG2 1 
ATOM   12207 N N   . PHE D 1 203 ? -12.179 -10.489 -53.185  1.00 20.84  ? 196  PHE D N   1 
ATOM   12208 C CA  . PHE D 1 203 ? -11.586 -9.588  -54.199  1.00 20.21  ? 196  PHE D CA  1 
ATOM   12209 C C   . PHE D 1 203 ? -10.418 -8.792  -53.616  1.00 18.79  ? 196  PHE D C   1 
ATOM   12210 O O   . PHE D 1 203 ? -9.618  -8.291  -54.411  1.00 18.38  ? 196  PHE D O   1 
ATOM   12211 C CB  . PHE D 1 203 ? -12.657 -8.660  -54.773  1.00 20.43  ? 196  PHE D CB  1 
ATOM   12212 C CG  . PHE D 1 203 ? -13.651 -9.331  -55.688  1.00 22.52  ? 196  PHE D CG  1 
ATOM   12213 C CD1 . PHE D 1 203 ? -13.419 -10.598 -56.207  1.00 24.15  ? 196  PHE D CD1 1 
ATOM   12214 C CD2 . PHE D 1 203 ? -14.795 -8.672  -56.081  1.00 23.27  ? 196  PHE D CD2 1 
ATOM   12215 C CE1 . PHE D 1 203 ? -14.315 -11.198 -57.077  1.00 24.49  ? 196  PHE D CE1 1 
ATOM   12216 C CE2 . PHE D 1 203 ? -15.702 -9.278  -56.939  1.00 25.31  ? 196  PHE D CE2 1 
ATOM   12217 C CZ  . PHE D 1 203 ? -15.461 -10.539 -57.437  1.00 25.85  ? 196  PHE D CZ  1 
ATOM   12218 N N   . ARG D 1 204 ? -10.305 -8.697  -52.292  1.00 19.62  ? 197  ARG D N   1 
ATOM   12219 C CA  . ARG D 1 204 ? -9.368  -7.756  -51.613  1.00 20.95  ? 197  ARG D CA  1 
ATOM   12220 C C   . ARG D 1 204 ? -8.205  -8.499  -50.938  1.00 22.53  ? 197  ARG D C   1 
ATOM   12221 O O   . ARG D 1 204 ? -7.075  -7.986  -51.005  1.00 23.75  ? 197  ARG D O   1 
ATOM   12222 C CB  . ARG D 1 204 ? -10.111 -6.915  -50.578  1.00 20.29  ? 197  ARG D CB  1 
ATOM   12223 C CG  . ARG D 1 204 ? -11.107 -5.929  -51.163  1.00 20.21  ? 197  ARG D CG  1 
ATOM   12224 C CD  . ARG D 1 204 ? -12.154 -5.528  -50.130  1.00 20.70  ? 197  ARG D CD  1 
ATOM   12225 N NE  . ARG D 1 204 ? -11.552 -5.059  -48.875  1.00 21.47  ? 197  ARG D NE  1 
ATOM   12226 C CZ  . ARG D 1 204 ? -11.077 -3.823  -48.644  1.00 20.97  ? 197  ARG D CZ  1 
ATOM   12227 N NH1 . ARG D 1 204 ? -11.162 -2.873  -49.566  1.00 22.17  ? 197  ARG D NH1 1 
ATOM   12228 N NH2 . ARG D 1 204 ? -10.536 -3.537  -47.472  1.00 18.30  ? 197  ARG D NH2 1 
ATOM   12229 N N   . LYS D 1 205 ? -8.478  -9.636  -50.293  1.00 25.55  ? 198  LYS D N   1 
ATOM   12230 C CA  . LYS D 1 205 ? -7.543  -10.295 -49.329  1.00 27.59  ? 198  LYS D CA  1 
ATOM   12231 C C   . LYS D 1 205 ? -6.210  -10.591 -50.014  1.00 25.20  ? 198  LYS D C   1 
ATOM   12232 O O   . LYS D 1 205 ? -5.167  -10.259 -49.472  1.00 25.92  ? 198  LYS D O   1 
ATOM   12233 C CB  . LYS D 1 205 ? -8.154  -11.555 -48.698  1.00 29.71  ? 198  LYS D CB  1 
ATOM   12234 C CG  . LYS D 1 205 ? -8.818  -11.308 -47.349  1.00 34.22  ? 198  LYS D CG  1 
ATOM   12235 C CD  . LYS D 1 205 ? -9.443  -12.524 -46.703  1.00 37.92  ? 198  LYS D CD  1 
ATOM   12236 C CE  . LYS D 1 205 ? -8.419  -13.371 -45.978  1.00 39.65  ? 198  LYS D CE  1 
ATOM   12237 N NZ  . LYS D 1 205 ? -8.789  -13.539 -44.558  1.00 43.85  ? 198  LYS D NZ  1 
ATOM   12238 N N   . PRO D 1 206 ? -6.183  -11.206 -51.218  1.00 22.73  ? 199  PRO D N   1 
ATOM   12239 C CA  . PRO D 1 206 ? -4.910  -11.533 -51.873  1.00 21.70  ? 199  PRO D CA  1 
ATOM   12240 C C   . PRO D 1 206 ? -3.986  -10.323 -52.110  1.00 20.14  ? 199  PRO D C   1 
ATOM   12241 O O   . PRO D 1 206 ? -2.782  -10.513 -52.188  1.00 18.59  ? 199  PRO D O   1 
ATOM   12242 C CB  . PRO D 1 206 ? -5.348  -12.161 -53.203  1.00 21.56  ? 199  PRO D CB  1 
ATOM   12243 C CG  . PRO D 1 206 ? -6.758  -12.666 -52.936  1.00 22.06  ? 199  PRO D CG  1 
ATOM   12244 C CD  . PRO D 1 206 ? -7.354  -11.647 -51.995  1.00 22.01  ? 199  PRO D CD  1 
ATOM   12245 N N   . PHE D 1 207 ? -4.566  -9.122  -52.177  1.00 19.15  ? 200  PHE D N   1 
ATOM   12246 C CA  . PHE D 1 207 ? -3.925  -7.885  -52.692  1.00 18.13  ? 200  PHE D CA  1 
ATOM   12247 C C   . PHE D 1 207 ? -3.652  -6.906  -51.548  1.00 17.71  ? 200  PHE D C   1 
ATOM   12248 O O   . PHE D 1 207 ? -3.078  -5.828  -51.766  1.00 17.30  ? 200  PHE D O   1 
ATOM   12249 C CB  . PHE D 1 207 ? -4.805  -7.314  -53.807  1.00 17.69  ? 200  PHE D CB  1 
ATOM   12250 C CG  . PHE D 1 207 ? -5.174  -8.361  -54.831  1.00 17.53  ? 200  PHE D CG  1 
ATOM   12251 C CD1 . PHE D 1 207 ? -4.217  -8.885  -55.686  1.00 17.08  ? 200  PHE D CD1 1 
ATOM   12252 C CD2 . PHE D 1 207 ? -6.466  -8.861  -54.907  1.00 18.28  ? 200  PHE D CD2 1 
ATOM   12253 C CE1 . PHE D 1 207 ? -4.537  -9.882  -56.593  1.00 17.41  ? 200  PHE D CE1 1 
ATOM   12254 C CE2 . PHE D 1 207 ? -6.796  -9.846  -55.823  1.00 17.86  ? 200  PHE D CE2 1 
ATOM   12255 C CZ  . PHE D 1 207 ? -5.828  -10.356 -56.660  1.00 18.74  ? 200  PHE D CZ  1 
ATOM   12256 N N   . MET D 1 208 ? -4.017  -7.272  -50.332  1.00 17.87  ? 201  MET D N   1 
ATOM   12257 C CA  . MET D 1 208 ? -3.682  -6.438  -49.155  1.00 19.37  ? 201  MET D CA  1 
ATOM   12258 C C   . MET D 1 208 ? -2.183  -6.538  -48.904  1.00 21.16  ? 201  MET D C   1 
ATOM   12259 O O   . MET D 1 208 ? -1.541  -7.521  -49.284  1.00 24.21  ? 201  MET D O   1 
ATOM   12260 C CB  . MET D 1 208 ? -4.447  -6.911  -47.928  1.00 19.31  ? 201  MET D CB  1 
ATOM   12261 C CG  . MET D 1 208 ? -5.923  -6.690  -48.055  1.00 19.39  ? 201  MET D CG  1 
ATOM   12262 S SD  . MET D 1 208 ? -6.782  -7.444  -46.670  1.00 20.12  ? 201  MET D SD  1 
ATOM   12263 C CE  . MET D 1 208 ? -8.470  -7.097  -47.172  1.00 22.66  ? 201  MET D CE  1 
ATOM   12264 N N   . PRO D 1 209 ? -1.556  -5.499  -48.317  1.00 21.36  ? 202  PRO D N   1 
ATOM   12265 C CA  . PRO D 1 209 ? -2.245  -4.277  -47.906  1.00 19.96  ? 202  PRO D CA  1 
ATOM   12266 C C   . PRO D 1 209 ? -2.637  -3.316  -49.029  1.00 19.79  ? 202  PRO D C   1 
ATOM   12267 O O   . PRO D 1 209 ? -1.824  -3.031  -49.895  1.00 18.85  ? 202  PRO D O   1 
ATOM   12268 C CB  . PRO D 1 209 ? -1.202  -3.554  -47.064  1.00 21.66  ? 202  PRO D CB  1 
ATOM   12269 C CG  . PRO D 1 209 ? 0.133   -4.021  -47.639  1.00 23.23  ? 202  PRO D CG  1 
ATOM   12270 C CD  . PRO D 1 209 ? -0.106  -5.459  -48.047  1.00 23.34  ? 202  PRO D CD  1 
ATOM   12271 N N   . LEU D 1 210 ? -3.879  -2.828  -48.960  1.00 19.40  ? 203  LEU D N   1 
ATOM   12272 C CA  . LEU D 1 210 ? -4.457  -1.865  -49.924  1.00 18.48  ? 203  LEU D CA  1 
ATOM   12273 C C   . LEU D 1 210 ? -4.186  -0.445  -49.440  1.00 18.34  ? 203  LEU D C   1 
ATOM   12274 O O   . LEU D 1 210 ? -3.334  -0.289  -48.557  1.00 19.93  ? 203  LEU D O   1 
ATOM   12275 C CB  . LEU D 1 210 ? -5.940  -2.185  -50.061  1.00 18.92  ? 203  LEU D CB  1 
ATOM   12276 C CG  . LEU D 1 210 ? -6.228  -3.551  -50.685  1.00 19.08  ? 203  LEU D CG  1 
ATOM   12277 C CD1 . LEU D 1 210 ? -7.716  -3.814  -50.767  1.00 18.67  ? 203  LEU D CD1 1 
ATOM   12278 C CD2 . LEU D 1 210 ? -5.614  -3.661  -52.084  1.00 19.21  ? 203  LEU D CD2 1 
ATOM   12279 N N   . LEU D 1 211 ? -4.798  0.561   -50.057  1.00 17.92  ? 204  LEU D N   1 
ATOM   12280 C CA  . LEU D 1 211 ? -4.600  1.957   -49.608  1.00 19.05  ? 204  LEU D CA  1 
ATOM   12281 C C   . LEU D 1 211 ? -4.983  2.011   -48.143  1.00 20.09  ? 204  LEU D C   1 
ATOM   12282 O O   . LEU D 1 211 ? -6.019  1.475   -47.752  1.00 21.00  ? 204  LEU D O   1 
ATOM   12283 C CB  . LEU D 1 211 ? -5.470  2.937   -50.391  1.00 18.12  ? 204  LEU D CB  1 
ATOM   12284 C CG  . LEU D 1 211 ? -5.037  3.207   -51.819  1.00 18.90  ? 204  LEU D CG  1 
ATOM   12285 C CD1 . LEU D 1 211 ? -6.005  4.186   -52.450  1.00 20.33  ? 204  LEU D CD1 1 
ATOM   12286 C CD2 . LEU D 1 211 ? -3.603  3.735   -51.901  1.00 19.28  ? 204  LEU D CD2 1 
ATOM   12287 N N   . PRO D 1 212 ? -4.183  2.688   -47.301  1.00 21.27  ? 205  PRO D N   1 
ATOM   12288 C CA  . PRO D 1 212 ? -4.579  2.904   -45.918  1.00 22.25  ? 205  PRO D CA  1 
ATOM   12289 C C   . PRO D 1 212 ? -5.729  3.926   -45.840  1.00 22.11  ? 205  PRO D C   1 
ATOM   12290 O O   . PRO D 1 212 ? -5.936  4.699   -46.764  1.00 21.18  ? 205  PRO D O   1 
ATOM   12291 C CB  . PRO D 1 212 ? -3.273  3.332   -45.230  1.00 22.87  ? 205  PRO D CB  1 
ATOM   12292 C CG  . PRO D 1 212 ? -2.384  3.872   -46.319  1.00 23.06  ? 205  PRO D CG  1 
ATOM   12293 C CD  . PRO D 1 212 ? -2.880  3.279   -47.630  1.00 23.42  ? 205  PRO D CD  1 
ATOM   12294 N N   . GLY D 1 213 ? -6.476  3.881   -44.747  1.00 21.87  ? 206  GLY D N   1 
ATOM   12295 C CA  . GLY D 1 213 ? -7.447  4.930   -44.392  1.00 23.14  ? 206  GLY D CA  1 
ATOM   12296 C C   . GLY D 1 213 ? -8.815  4.679   -44.995  1.00 23.16  ? 206  GLY D C   1 
ATOM   12297 O O   . GLY D 1 213 ? -9.590  5.644   -45.064  1.00 22.58  ? 206  GLY D O   1 
ATOM   12298 N N   . PHE D 1 214 ? -9.099  3.440   -45.421  1.00 23.89  ? 207  PHE D N   1 
ATOM   12299 C CA  . PHE D 1 214 ? -10.390 3.026   -46.034  1.00 23.97  ? 207  PHE D CA  1 
ATOM   12300 C C   . PHE D 1 214 ? -11.160 2.192   -45.009  1.00 24.33  ? 207  PHE D C   1 
ATOM   12301 O O   . PHE D 1 214 ? -10.622 1.166   -44.511  1.00 22.73  ? 207  PHE D O   1 
ATOM   12302 C CB  . PHE D 1 214 ? -10.184 2.304   -47.370  1.00 24.14  ? 207  PHE D CB  1 
ATOM   12303 C CG  . PHE D 1 214 ? -9.973  3.245   -48.537  1.00 25.13  ? 207  PHE D CG  1 
ATOM   12304 C CD1 . PHE D 1 214 ? -8.780  3.950   -48.675  1.00 25.07  ? 207  PHE D CD1 1 
ATOM   12305 C CD2 . PHE D 1 214 ? -10.969 3.447   -49.486  1.00 25.29  ? 207  PHE D CD2 1 
ATOM   12306 C CE1 . PHE D 1 214 ? -8.586  4.822   -49.734  1.00 25.37  ? 207  PHE D CE1 1 
ATOM   12307 C CE2 . PHE D 1 214 ? -10.766 4.322   -50.543  1.00 24.75  ? 207  PHE D CE2 1 
ATOM   12308 C CZ  . PHE D 1 214 ? -9.581  5.005   -50.668  1.00 23.97  ? 207  PHE D CZ  1 
ATOM   12309 N N   A ARG D 1 215 ? -12.378 2.646   -44.691  0.43 23.67  ? 208  ARG D N   1 
ATOM   12310 N N   B ARG D 1 215 ? -12.392 2.628   -44.709  0.57 24.12  ? 208  ARG D N   1 
ATOM   12311 C CA  A ARG D 1 215 ? -13.297 1.999   -43.725  0.43 23.13  ? 208  ARG D CA  1 
ATOM   12312 C CA  B ARG D 1 215 ? -13.304 2.016   -43.716  0.57 23.69  ? 208  ARG D CA  1 
ATOM   12313 C C   A ARG D 1 215 ? -14.660 1.795   -44.391  0.43 22.84  ? 208  ARG D C   1 
ATOM   12314 C C   B ARG D 1 215 ? -14.673 1.808   -44.368  0.57 23.11  ? 208  ARG D C   1 
ATOM   12315 O O   A ARG D 1 215 ? -15.023 2.599   -45.281  0.43 22.22  ? 208  ARG D O   1 
ATOM   12316 O O   B ARG D 1 215 ? -15.076 2.642   -45.206  0.57 22.21  ? 208  ARG D O   1 
ATOM   12317 C CB  A ARG D 1 215 ? -13.395 2.856   -42.461  0.43 23.90  ? 208  ARG D CB  1 
ATOM   12318 C CB  B ARG D 1 215 ? -13.428 2.932   -42.495  0.57 25.29  ? 208  ARG D CB  1 
ATOM   12319 C CG  A ARG D 1 215 ? -12.063 3.090   -41.761  0.43 23.83  ? 208  ARG D CG  1 
ATOM   12320 C CG  B ARG D 1 215 ? -12.142 3.172   -41.707  0.57 25.63  ? 208  ARG D CG  1 
ATOM   12321 C CD  A ARG D 1 215 ? -11.555 1.855   -41.041  0.43 23.86  ? 208  ARG D CD  1 
ATOM   12322 C CD  B ARG D 1 215 ? -12.337 4.350   -40.757  0.57 26.72  ? 208  ARG D CD  1 
ATOM   12323 N NE  A ARG D 1 215 ? -10.353 2.182   -40.294  0.43 24.79  ? 208  ARG D NE  1 
ATOM   12324 N NE  B ARG D 1 215 ? -11.626 4.358   -39.467  0.57 26.24  ? 208  ARG D NE  1 
ATOM   12325 C CZ  A ARG D 1 215 ? -9.126  2.147   -40.800  0.43 24.57  ? 208  ARG D CZ  1 
ATOM   12326 C CZ  B ARG D 1 215 ? -10.381 4.795   -39.305  0.57 26.51  ? 208  ARG D CZ  1 
ATOM   12327 N NH1 A ARG D 1 215 ? -8.931  1.772   -42.054  0.43 24.44  ? 208  ARG D NH1 1 
ATOM   12328 N NH1 B ARG D 1 215 ? -9.835  4.806   -38.103  0.57 26.46  ? 208  ARG D NH1 1 
ATOM   12329 N NH2 A ARG D 1 215 ? -8.097  2.472   -40.040  0.43 24.18  ? 208  ARG D NH2 1 
ATOM   12330 N NH2 B ARG D 1 215 ? -9.669  5.191   -40.352  0.57 26.82  ? 208  ARG D NH2 1 
ATOM   12331 N N   . HIS D 1 216 ? -15.379 0.754   -43.966  1.00 22.92  ? 209  HIS D N   1 
ATOM   12332 C CA  . HIS D 1 216 ? -16.671 0.339   -44.562  1.00 22.74  ? 209  HIS D CA  1 
ATOM   12333 C C   . HIS D 1 216 ? -17.781 0.367   -43.502  1.00 21.98  ? 209  HIS D C   1 
ATOM   12334 O O   . HIS D 1 216 ? -17.568 -0.131  -42.378  1.00 20.89  ? 209  HIS D O   1 
ATOM   12335 C CB  . HIS D 1 216 ? -16.484 -1.020  -45.250  1.00 23.33  ? 209  HIS D CB  1 
ATOM   12336 C CG  . HIS D 1 216 ? -15.674 -0.942  -46.504  1.00 24.47  ? 209  HIS D CG  1 
ATOM   12337 N ND1 . HIS D 1 216 ? -14.292 -1.017  -46.490  1.00 23.95  ? 209  HIS D ND1 1 
ATOM   12338 C CD2 . HIS D 1 216 ? -16.032 -0.790  -47.797  1.00 23.58  ? 209  HIS D CD2 1 
ATOM   12339 C CE1 . HIS D 1 216 ? -13.839 -0.920  -47.724  1.00 24.10  ? 209  HIS D CE1 1 
ATOM   12340 N NE2 . HIS D 1 216 ? -14.880 -0.774  -48.540  1.00 24.24  ? 209  HIS D NE2 1 
ATOM   12341 N N   . VAL D 1 217 ? -18.932 0.927   -43.874  1.00 21.45  ? 210  VAL D N   1 
ATOM   12342 C CA  . VAL D 1 217 ? -20.190 0.935   -43.069  1.00 19.36  ? 210  VAL D CA  1 
ATOM   12343 C C   . VAL D 1 217 ? -21.233 0.149   -43.857  1.00 19.54  ? 210  VAL D C   1 
ATOM   12344 O O   . VAL D 1 217 ? -21.031 -0.106  -45.043  1.00 19.21  ? 210  VAL D O   1 
ATOM   12345 C CB  . VAL D 1 217 ? -20.625 2.379   -42.739  1.00 18.16  ? 210  VAL D CB  1 
ATOM   12346 C CG1 . VAL D 1 217 ? -19.576 3.078   -41.897  1.00 18.48  ? 210  VAL D CG1 1 
ATOM   12347 C CG2 . VAL D 1 217 ? -20.928 3.216   -43.973  1.00 17.54  ? 210  VAL D CG2 1 
ATOM   12348 N N   . PRO D 1 218 ? -22.331 -0.328  -43.221  1.00 21.19  ? 211  PRO D N   1 
ATOM   12349 C CA  . PRO D 1 218 ? -23.449 -0.939  -43.935  1.00 20.46  ? 211  PRO D CA  1 
ATOM   12350 C C   . PRO D 1 218 ? -24.097 0.067   -44.889  1.00 20.59  ? 211  PRO D C   1 
ATOM   12351 O O   . PRO D 1 218 ? -24.212 1.234   -44.543  1.00 20.79  ? 211  PRO D O   1 
ATOM   12352 C CB  . PRO D 1 218 ? -24.450 -1.351  -42.848  1.00 20.06  ? 211  PRO D CB  1 
ATOM   12353 C CG  . PRO D 1 218 ? -23.650 -1.401  -41.586  1.00 21.21  ? 211  PRO D CG  1 
ATOM   12354 C CD  . PRO D 1 218 ? -22.541 -0.379  -41.765  1.00 22.14  ? 211  PRO D CD  1 
ATOM   12355 N N   . PHE D 1 219 ? -24.478 -0.421  -46.066  1.00 20.96  ? 212  PHE D N   1 
ATOM   12356 C CA  . PHE D 1 219 ? -25.192 0.347   -47.110  1.00 21.31  ? 212  PHE D CA  1 
ATOM   12357 C C   . PHE D 1 219 ? -26.627 0.569   -46.636  1.00 21.33  ? 212  PHE D C   1 
ATOM   12358 O O   . PHE D 1 219 ? -27.239 -0.397  -46.145  1.00 21.81  ? 212  PHE D O   1 
ATOM   12359 C CB  . PHE D 1 219 ? -25.150 -0.413  -48.438  1.00 21.75  ? 212  PHE D CB  1 
ATOM   12360 C CG  . PHE D 1 219 ? -25.773 0.339   -49.582  1.00 21.38  ? 212  PHE D CG  1 
ATOM   12361 C CD1 . PHE D 1 219 ? -25.190 1.494   -50.061  1.00 21.65  ? 212  PHE D CD1 1 
ATOM   12362 C CD2 . PHE D 1 219 ? -26.962 -0.079  -50.138  1.00 21.73  ? 212  PHE D CD2 1 
ATOM   12363 C CE1 . PHE D 1 219 ? -25.780 2.218   -51.077  1.00 23.82  ? 212  PHE D CE1 1 
ATOM   12364 C CE2 . PHE D 1 219 ? -27.538 0.628   -51.178  1.00 23.83  ? 212  PHE D CE2 1 
ATOM   12365 C CZ  . PHE D 1 219 ? -26.943 1.774   -51.654  1.00 24.26  ? 212  PHE D CZ  1 
ATOM   12366 N N   . GLY D 1 220 ? -27.128 1.799   -46.778  1.00 22.33  ? 213  GLY D N   1 
ATOM   12367 C CA  . GLY D 1 220 ? -28.535 2.166   -46.514  1.00 22.67  ? 213  GLY D CA  1 
ATOM   12368 C C   . GLY D 1 220 ? -28.793 2.378   -45.030  1.00 23.86  ? 213  GLY D C   1 
ATOM   12369 O O   . GLY D 1 220 ? -29.985 2.368   -44.637  1.00 26.48  ? 213  GLY D O   1 
ATOM   12370 N N   . ASN D 1 221 ? -27.722 2.577   -44.234  1.00 23.53  ? 214  ASN D N   1 
ATOM   12371 C CA  . ASN D 1 221 ? -27.750 2.776   -42.759  1.00 21.54  ? 214  ASN D CA  1 
ATOM   12372 C C   . ASN D 1 221 ? -27.089 4.107   -42.415  1.00 20.16  ? 214  ASN D C   1 
ATOM   12373 O O   . ASN D 1 221 ? -25.910 4.100   -42.138  1.00 18.19  ? 214  ASN D O   1 
ATOM   12374 C CB  . ASN D 1 221 ? -27.065 1.613   -42.049  1.00 21.38  ? 214  ASN D CB  1 
ATOM   12375 C CG  . ASN D 1 221 ? -27.146 1.673   -40.543  1.00 21.18  ? 214  ASN D CG  1 
ATOM   12376 O OD1 . ASN D 1 221 ? -27.337 2.730   -39.949  1.00 22.31  ? 214  ASN D OD1 1 
ATOM   12377 N ND2 . ASN D 1 221 ? -26.960 0.530   -39.912  1.00 21.48  ? 214  ASN D ND2 1 
ATOM   12378 N N   . ILE D 1 222 ? -27.854 5.195   -42.427  1.00 21.13  ? 215  ILE D N   1 
ATOM   12379 C CA  . ILE D 1 222 ? -27.347 6.577   -42.197  1.00 22.80  ? 215  ILE D CA  1 
ATOM   12380 C C   . ILE D 1 222 ? -26.750 6.679   -40.795  1.00 25.71  ? 215  ILE D C   1 
ATOM   12381 O O   . ILE D 1 222 ? -25.782 7.441   -40.623  1.00 26.50  ? 215  ILE D O   1 
ATOM   12382 C CB  . ILE D 1 222 ? -28.442 7.642   -42.426  1.00 22.25  ? 215  ILE D CB  1 
ATOM   12383 C CG1 . ILE D 1 222 ? -27.846 9.052   -42.509  1.00 23.05  ? 215  ILE D CG1 1 
ATOM   12384 C CG2 . ILE D 1 222 ? -29.532 7.556   -41.385  1.00 21.29  ? 215  ILE D CG2 1 
ATOM   12385 C CD1 . ILE D 1 222 ? -26.920 9.275   -43.727  1.00 23.54  ? 215  ILE D CD1 1 
ATOM   12386 N N   . GLU D 1 223 ? -27.279 5.950   -39.823  1.00 27.63  ? 216  GLU D N   1 
ATOM   12387 C CA  . GLU D 1 223 ? -26.803 6.106   -38.425  1.00 31.68  ? 216  GLU D CA  1 
ATOM   12388 C C   . GLU D 1 223 ? -25.402 5.505   -38.293  1.00 28.68  ? 216  GLU D C   1 
ATOM   12389 O O   . GLU D 1 223 ? -24.542 6.180   -37.676  1.00 24.13  ? 216  GLU D O   1 
ATOM   12390 C CB  . GLU D 1 223 ? -27.856 5.601   -37.441  1.00 38.07  ? 216  GLU D CB  1 
ATOM   12391 C CG  . GLU D 1 223 ? -28.994 6.608   -37.270  1.00 44.05  ? 216  GLU D CG  1 
ATOM   12392 C CD  . GLU D 1 223 ? -28.540 8.051   -37.020  1.00 52.64  ? 216  GLU D CD  1 
ATOM   12393 O OE1 . GLU D 1 223 ? -27.561 8.245   -36.263  1.00 50.41  ? 216  GLU D OE1 1 
ATOM   12394 O OE2 . GLU D 1 223 ? -29.144 8.992   -37.600  1.00 62.29  ? 216  GLU D OE2 1 
ATOM   12395 N N   . ALA D 1 224 ? -25.169 4.335   -38.896  1.00 27.55  ? 217  ALA D N   1 
ATOM   12396 C CA  . ALA D 1 224 ? -23.851 3.653   -38.935  1.00 26.36  ? 217  ALA D CA  1 
ATOM   12397 C C   . ALA D 1 224 ? -22.810 4.584   -39.565  1.00 26.59  ? 217  ALA D C   1 
ATOM   12398 O O   . ALA D 1 224 ? -21.672 4.649   -39.073  1.00 25.93  ? 217  ALA D O   1 
ATOM   12399 C CB  . ALA D 1 224 ? -23.954 2.373   -39.717  1.00 25.88  ? 217  ALA D CB  1 
ATOM   12400 N N   . MET D 1 225 ? -23.207 5.291   -40.618  1.00 25.12  ? 218  MET D N   1 
ATOM   12401 C CA  . MET D 1 225 ? -22.316 6.218   -41.347  1.00 24.84  ? 218  MET D CA  1 
ATOM   12402 C C   . MET D 1 225 ? -22.035 7.442   -40.471  1.00 23.77  ? 218  MET D C   1 
ATOM   12403 O O   . MET D 1 225 ? -20.892 7.856   -40.424  1.00 24.26  ? 218  MET D O   1 
ATOM   12404 C CB  . MET D 1 225 ? -22.918 6.655   -42.687  1.00 26.32  ? 218  MET D CB  1 
ATOM   12405 C CG  . MET D 1 225 ? -21.889 7.274   -43.613  1.00 28.35  ? 218  MET D CG  1 
ATOM   12406 S SD  . MET D 1 225 ? -22.581 7.845   -45.147  1.00 32.56  ? 218  MET D SD  1 
ATOM   12407 C CE  . MET D 1 225 ? -22.321 6.395   -46.169  1.00 34.24  ? 218  MET D CE  1 
ATOM   12408 N N   . ARG D 1 226 ? -23.043 8.030   -39.840  1.00 25.04  ? 219  ARG D N   1 
ATOM   12409 C CA  . ARG D 1 226 ? -22.860 9.179   -38.909  1.00 26.22  ? 219  ARG D CA  1 
ATOM   12410 C C   . ARG D 1 226 ? -21.816 8.800   -37.859  1.00 24.52  ? 219  ARG D C   1 
ATOM   12411 O O   . ARG D 1 226 ? -20.860 9.576   -37.643  1.00 23.98  ? 219  ARG D O   1 
ATOM   12412 C CB  . ARG D 1 226 ? -24.176 9.544   -38.210  1.00 28.18  ? 219  ARG D CB  1 
ATOM   12413 C CG  . ARG D 1 226 ? -24.014 10.596  -37.121  1.00 31.52  ? 219  ARG D CG  1 
ATOM   12414 C CD  . ARG D 1 226 ? -25.296 11.284  -36.693  1.00 32.80  ? 219  ARG D CD  1 
ATOM   12415 N NE  . ARG D 1 226 ? -25.752 12.229  -37.696  1.00 34.68  ? 219  ARG D NE  1 
ATOM   12416 C CZ  . ARG D 1 226 ? -25.289 13.470  -37.870  1.00 37.88  ? 219  ARG D CZ  1 
ATOM   12417 N NH1 . ARG D 1 226 ? -24.331 13.970  -37.108  1.00 41.01  ? 219  ARG D NH1 1 
ATOM   12418 N NH2 . ARG D 1 226 ? -25.785 14.203  -38.849  1.00 43.32  ? 219  ARG D NH2 1 
ATOM   12419 N N   . THR D 1 227 ? -22.009 7.638   -37.239  1.00 23.42  ? 220  THR D N   1 
ATOM   12420 C CA  . THR D 1 227 ? -21.117 7.079   -36.201  1.00 24.13  ? 220  THR D CA  1 
ATOM   12421 C C   . THR D 1 227 ? -19.681 7.092   -36.741  1.00 25.12  ? 220  THR D C   1 
ATOM   12422 O O   . THR D 1 227 ? -18.783 7.591   -36.042  1.00 26.82  ? 220  THR D O   1 
ATOM   12423 C CB  . THR D 1 227 ? -21.579 5.677   -35.784  1.00 24.07  ? 220  THR D CB  1 
ATOM   12424 O OG1 . THR D 1 227 ? -22.806 5.805   -35.066  1.00 23.75  ? 220  THR D OG1 1 
ATOM   12425 C CG2 . THR D 1 227 ? -20.569 4.961   -34.916  1.00 23.53  ? 220  THR D CG2 1 
ATOM   12426 N N   . ALA D 1 228 ? -19.474 6.547   -37.933  1.00 22.97  ? 221  ALA D N   1 
ATOM   12427 C CA  . ALA D 1 228 ? -18.138 6.348   -38.527  1.00 23.11  ? 221  ALA D CA  1 
ATOM   12428 C C   . ALA D 1 228 ? -17.474 7.713   -38.717  1.00 24.29  ? 221  ALA D C   1 
ATOM   12429 O O   . ALA D 1 228 ? -16.271 7.836   -38.360  1.00 21.44  ? 221  ALA D O   1 
ATOM   12430 C CB  . ALA D 1 228 ? -18.232 5.573   -39.808  1.00 22.06  ? 221  ALA D CB  1 
ATOM   12431 N N   . LEU D 1 229 ? -18.228 8.702   -39.218  1.00 24.35  ? 222  LEU D N   1 
ATOM   12432 C CA  . LEU D 1 229 ? -17.705 10.074  -39.471  1.00 25.50  ? 222  LEU D CA  1 
ATOM   12433 C C   . LEU D 1 229 ? -17.361 10.732  -38.137  1.00 25.56  ? 222  LEU D C   1 
ATOM   12434 O O   . LEU D 1 229 ? -16.316 11.399  -38.042  1.00 22.75  ? 222  LEU D O   1 
ATOM   12435 C CB  . LEU D 1 229 ? -18.745 10.904  -40.226  1.00 26.23  ? 222  LEU D CB  1 
ATOM   12436 C CG  . LEU D 1 229 ? -18.517 11.013  -41.732  1.00 28.03  ? 222  LEU D CG  1 
ATOM   12437 C CD1 . LEU D 1 229 ? -18.579 9.649   -42.410  1.00 27.30  ? 222  LEU D CD1 1 
ATOM   12438 C CD2 . LEU D 1 229 ? -19.520 11.960  -42.357  1.00 30.36  ? 222  LEU D CD2 1 
ATOM   12439 N N   . ASN D 1 230 ? -18.243 10.537  -37.165  1.00 24.50  ? 223  ASN D N   1 
ATOM   12440 C CA  . ASN D 1 230 ? -18.124 11.162  -35.832  1.00 27.50  ? 223  ASN D CA  1 
ATOM   12441 C C   . ASN D 1 230 ? -16.908 10.592  -35.094  1.00 26.09  ? 223  ASN D C   1 
ATOM   12442 O O   . ASN D 1 230 ? -16.147 11.399  -34.534  1.00 24.09  ? 223  ASN D O   1 
ATOM   12443 C CB  . ASN D 1 230 ? -19.411 10.988  -35.033  1.00 28.79  ? 223  ASN D CB  1 
ATOM   12444 C CG  . ASN D 1 230 ? -19.497 12.030  -33.954  1.00 32.21  ? 223  ASN D CG  1 
ATOM   12445 O OD1 . ASN D 1 230 ? -19.263 13.207  -34.219  1.00 34.31  ? 223  ASN D OD1 1 
ATOM   12446 N ND2 . ASN D 1 230 ? -19.773 11.597  -32.738  1.00 35.50  ? 223  ASN D ND2 1 
ATOM   12447 N N   . GLU D 1 231 ? -16.759 9.258   -35.087  1.00 26.85  ? 224  GLU D N   1 
ATOM   12448 C CA  . GLU D 1 231 ? -15.657 8.523   -34.406  1.00 27.40  ? 224  GLU D CA  1 
ATOM   12449 C C   . GLU D 1 231 ? -14.338 8.909   -35.075  1.00 27.05  ? 224  GLU D C   1 
ATOM   12450 O O   . GLU D 1 231 ? -13.367 9.123   -34.338  1.00 25.68  ? 224  GLU D O   1 
ATOM   12451 C CB  . GLU D 1 231 ? -15.869 7.008   -34.449  1.00 29.71  ? 224  GLU D CB  1 
ATOM   12452 C CG  . GLU D 1 231 ? -17.062 6.543   -33.631  1.00 32.75  ? 224  GLU D CG  1 
ATOM   12453 C CD  . GLU D 1 231 ? -16.983 6.665   -32.113  1.00 36.51  ? 224  GLU D CD  1 
ATOM   12454 O OE1 . GLU D 1 231 ? -16.053 6.063   -31.530  1.00 37.46  ? 224  GLU D OE1 1 
ATOM   12455 O OE2 . GLU D 1 231 ? -17.903 7.282   -31.499  1.00 40.69  ? 224  GLU D OE2 1 
ATOM   12456 N N   . CYS D 1 232 ? -14.313 9.016   -36.409  1.00 24.66  ? 225  CYS D N   1 
ATOM   12457 C CA  . CYS D 1 232 ? -13.119 9.451   -37.170  1.00 24.63  ? 225  CYS D CA  1 
ATOM   12458 C C   . CYS D 1 232 ? -12.730 10.882  -36.773  1.00 24.48  ? 225  CYS D C   1 
ATOM   12459 O O   . CYS D 1 232 ? -11.517 11.145  -36.633  1.00 24.78  ? 225  CYS D O   1 
ATOM   12460 C CB  . CYS D 1 232 ? -13.338 9.294   -38.669  1.00 25.75  ? 225  CYS D CB  1 
ATOM   12461 S SG  . CYS D 1 232 ? -13.129 7.575   -39.212  1.00 26.35  ? 225  CYS D SG  1 
ATOM   12462 N N   . LYS D 1 233 ? -13.711 11.756  -36.559  1.00 25.39  ? 226  LYS D N   1 
ATOM   12463 C CA  . LYS D 1 233 ? -13.492 13.159  -36.111  1.00 27.38  ? 226  LYS D CA  1 
ATOM   12464 C C   . LYS D 1 233 ? -12.894 13.177  -34.693  1.00 26.20  ? 226  LYS D C   1 
ATOM   12465 O O   . LYS D 1 233 ? -11.897 13.913  -34.456  1.00 23.84  ? 226  LYS D O   1 
ATOM   12466 C CB  . LYS D 1 233 ? -14.816 13.919  -36.145  1.00 29.92  ? 226  LYS D CB  1 
ATOM   12467 C CG  . LYS D 1 233 ? -14.737 15.348  -35.648  1.00 33.21  ? 226  LYS D CG  1 
ATOM   12468 C CD  . LYS D 1 233 ? -16.037 16.111  -35.834  1.00 37.99  ? 226  LYS D CD  1 
ATOM   12469 C CE  . LYS D 1 233 ? -15.820 17.576  -36.192  1.00 43.22  ? 226  LYS D CE  1 
ATOM   12470 N NZ  . LYS D 1 233 ? -15.363 18.417  -35.055  1.00 46.64  ? 226  LYS D NZ  1 
ATOM   12471 N N   . LYS D 1 234 ? -13.474 12.391  -33.785  1.00 24.79  ? 227  LYS D N   1 
ATOM   12472 C CA  . LYS D 1 234 ? -12.999 12.284  -32.376  1.00 25.78  ? 227  LYS D CA  1 
ATOM   12473 C C   . LYS D 1 234 ? -11.520 11.855  -32.322  1.00 24.02  ? 227  LYS D C   1 
ATOM   12474 O O   . LYS D 1 234 ? -10.801 12.408  -31.493  1.00 23.29  ? 227  LYS D O   1 
ATOM   12475 C CB  . LYS D 1 234 ? -13.862 11.307  -31.577  1.00 28.06  ? 227  LYS D CB  1 
ATOM   12476 C CG  . LYS D 1 234 ? -15.307 11.743  -31.359  1.00 30.61  ? 227  LYS D CG  1 
ATOM   12477 C CD  . LYS D 1 234 ? -15.981 10.996  -30.219  1.00 34.55  ? 227  LYS D CD  1 
ATOM   12478 C CE  . LYS D 1 234 ? -17.348 10.429  -30.580  1.00 37.72  ? 227  LYS D CE  1 
ATOM   12479 N NZ  . LYS D 1 234 ? -17.992 9.723   -29.447  1.00 39.87  ? 227  LYS D NZ  1 
ATOM   12480 N N   . THR D 1 235 ? -11.087 10.907  -33.159  1.00 23.34  ? 228  THR D N   1 
ATOM   12481 C CA  . THR D 1 235 ? -9.754  10.247  -33.082  1.00 22.64  ? 228  THR D CA  1 
ATOM   12482 C C   . THR D 1 235 ? -8.744  10.973  -33.965  1.00 21.41  ? 228  THR D C   1 
ATOM   12483 O O   . THR D 1 235 ? -7.588  10.509  -34.018  1.00 22.14  ? 228  THR D O   1 
ATOM   12484 C CB  . THR D 1 235 ? -9.840  8.764   -33.459  1.00 23.54  ? 228  THR D CB  1 
ATOM   12485 O OG1 . THR D 1 235 ? -10.305 8.660   -34.809  1.00 24.70  ? 228  THR D OG1 1 
ATOM   12486 C CG2 . THR D 1 235 ? -10.752 7.994   -32.525  1.00 23.02  ? 228  THR D CG2 1 
ATOM   12487 N N   . GLY D 1 236 ? -9.150  12.061  -34.621  1.00 20.35  ? 229  GLY D N   1 
ATOM   12488 C CA  . GLY D 1 236 ? -8.260  12.851  -35.493  1.00 21.08  ? 229  GLY D CA  1 
ATOM   12489 C C   . GLY D 1 236 ? -7.995  12.203  -36.861  1.00 20.95  ? 229  GLY D C   1 
ATOM   12490 O O   . GLY D 1 236 ? -7.034  12.649  -37.519  1.00 18.61  ? 229  GLY D O   1 
ATOM   12491 N N   . ASP D 1 237 ? -8.837  11.241  -37.286  1.00 21.39  ? 230  ASP D N   1 
ATOM   12492 C CA  . ASP D 1 237 ? -8.753  10.506  -38.580  1.00 21.43  ? 230  ASP D CA  1 
ATOM   12493 C C   . ASP D 1 237 ? -9.923  10.943  -39.463  1.00 20.42  ? 230  ASP D C   1 
ATOM   12494 O O   . ASP D 1 237 ? -10.629 10.078  -40.005  1.00 17.47  ? 230  ASP D O   1 
ATOM   12495 C CB  . ASP D 1 237 ? -8.810  8.987   -38.383  1.00 22.73  ? 230  ASP D CB  1 
ATOM   12496 C CG  . ASP D 1 237 ? -7.807  8.424   -37.400  1.00 23.93  ? 230  ASP D CG  1 
ATOM   12497 O OD1 . ASP D 1 237 ? -6.606  8.353   -37.758  1.00 27.38  ? 230  ASP D OD1 1 
ATOM   12498 O OD2 . ASP D 1 237 ? -8.235  8.059   -36.286  1.00 24.33  ? 230  ASP D OD2 1 
ATOM   12499 N N   . ASP D 1 238 ? -10.092 12.254  -39.612  1.00 21.14  ? 231  ASP D N   1 
ATOM   12500 C CA  . ASP D 1 238 ? -11.270 12.901  -40.247  1.00 21.55  ? 231  ASP D CA  1 
ATOM   12501 C C   . ASP D 1 238 ? -11.458 12.375  -41.669  1.00 20.13  ? 231  ASP D C   1 
ATOM   12502 O O   . ASP D 1 238 ? -10.482 12.085  -42.367  1.00 21.25  ? 231  ASP D O   1 
ATOM   12503 C CB  . ASP D 1 238 ? -11.152 14.427  -40.243  1.00 23.81  ? 231  ASP D CB  1 
ATOM   12504 C CG  . ASP D 1 238 ? -10.928 15.002  -38.848  1.00 28.30  ? 231  ASP D CG  1 
ATOM   12505 O OD1 . ASP D 1 238 ? -9.774  14.925  -38.358  1.00 30.68  ? 231  ASP D OD1 1 
ATOM   12506 O OD2 . ASP D 1 238 ? -11.912 15.481  -38.228  1.00 31.66  ? 231  ASP D OD2 1 
ATOM   12507 N N   . VAL D 1 239 ? -12.708 12.284  -42.090  1.00 20.82  ? 232  VAL D N   1 
ATOM   12508 C CA  . VAL D 1 239 ? -13.106 11.621  -43.364  1.00 21.43  ? 232  VAL D CA  1 
ATOM   12509 C C   . VAL D 1 239 ? -12.976 12.648  -44.496  1.00 20.88  ? 232  VAL D C   1 
ATOM   12510 O O   . VAL D 1 239 ? -13.565 13.746  -44.386  1.00 20.75  ? 232  VAL D O   1 
ATOM   12511 C CB  . VAL D 1 239 ? -14.521 11.030  -43.223  1.00 20.33  ? 232  VAL D CB  1 
ATOM   12512 C CG1 . VAL D 1 239 ? -15.100 10.568  -44.545  1.00 20.85  ? 232  VAL D CG1 1 
ATOM   12513 C CG2 . VAL D 1 239 ? -14.513 9.896   -42.207  1.00 20.34  ? 232  VAL D CG2 1 
ATOM   12514 N N   . ALA D 1 240 ? -12.195 12.301  -45.517  1.00 21.55  ? 233  ALA D N   1 
ATOM   12515 C CA  . ALA D 1 240 ? -11.993 13.105  -46.748  1.00 20.66  ? 233  ALA D CA  1 
ATOM   12516 C C   . ALA D 1 240 ? -13.239 12.989  -47.624  1.00 20.33  ? 233  ALA D C   1 
ATOM   12517 O O   . ALA D 1 240 ? -13.711 14.026  -48.136  1.00 21.27  ? 233  ALA D O   1 
ATOM   12518 C CB  . ALA D 1 240 ? -10.755 12.645  -47.479  1.00 20.32  ? 233  ALA D CB  1 
ATOM   12519 N N   . ALA D 1 241 ? -13.756 11.770  -47.789  1.00 19.35  ? 234  ALA D N   1 
ATOM   12520 C CA  . ALA D 1 241 ? -14.867 11.504  -48.720  1.00 17.47  ? 234  ALA D CA  1 
ATOM   12521 C C   . ALA D 1 241 ? -15.637 10.267  -48.293  1.00 17.27  ? 234  ALA D C   1 
ATOM   12522 O O   . ALA D 1 241 ? -15.053 9.338   -47.724  1.00 15.55  ? 234  ALA D O   1 
ATOM   12523 C CB  . ALA D 1 241 ? -14.326 11.338  -50.120  1.00 17.68  ? 234  ALA D CB  1 
ATOM   12524 N N   . VAL D 1 242 ? -16.919 10.288  -48.621  1.00 19.48  ? 235  VAL D N   1 
ATOM   12525 C CA  . VAL D 1 242 ? -17.777 9.081   -48.716  1.00 19.69  ? 235  VAL D CA  1 
ATOM   12526 C C   . VAL D 1 242 ? -17.940 8.736   -50.191  1.00 18.95  ? 235  VAL D C   1 
ATOM   12527 O O   . VAL D 1 242 ? -18.265 9.644   -50.986  1.00 18.92  ? 235  VAL D O   1 
ATOM   12528 C CB  . VAL D 1 242 ? -19.138 9.322   -48.055  1.00 20.03  ? 235  VAL D CB  1 
ATOM   12529 C CG1 . VAL D 1 242 ? -20.015 8.084   -48.106  1.00 19.80  ? 235  VAL D CG1 1 
ATOM   12530 C CG2 . VAL D 1 242 ? -18.960 9.786   -46.618  1.00 21.65  ? 235  VAL D CG2 1 
ATOM   12531 N N   . ILE D 1 243 ? -17.729 7.468   -50.524  1.00 19.06  ? 236  ILE D N   1 
ATOM   12532 C CA  . ILE D 1 243 ? -18.009 6.940   -51.883  1.00 20.04  ? 236  ILE D CA  1 
ATOM   12533 C C   . ILE D 1 243 ? -19.068 5.853   -51.741  1.00 20.70  ? 236  ILE D C   1 
ATOM   12534 O O   . ILE D 1 243 ? -18.895 4.974   -50.880  1.00 20.05  ? 236  ILE D O   1 
ATOM   12535 C CB  . ILE D 1 243 ? -16.740 6.410   -52.572  1.00 20.11  ? 236  ILE D CB  1 
ATOM   12536 C CG1 . ILE D 1 243 ? -17.041 5.943   -54.000  1.00 20.31  ? 236  ILE D CG1 1 
ATOM   12537 C CG2 . ILE D 1 243 ? -16.087 5.307   -51.750  1.00 20.13  ? 236  ILE D CG2 1 
ATOM   12538 C CD1 . ILE D 1 243 ? -15.790 5.560   -54.792  1.00 20.10  ? 236  ILE D CD1 1 
ATOM   12539 N N   . LEU D 1 244 ? -20.087 5.886   -52.603  1.00 23.45  ? 237  LEU D N   1 
ATOM   12540 C CA  . LEU D 1 244 ? -21.146 4.847   -52.633  1.00 23.49  ? 237  LEU D CA  1 
ATOM   12541 C C   . LEU D 1 244 ? -21.790 4.809   -54.009  1.00 21.74  ? 237  LEU D C   1 
ATOM   12542 O O   . LEU D 1 244 ? -21.774 5.840   -54.728  1.00 21.98  ? 237  LEU D O   1 
ATOM   12543 C CB  . LEU D 1 244 ? -22.166 5.104   -51.513  1.00 26.55  ? 237  LEU D CB  1 
ATOM   12544 C CG  . LEU D 1 244 ? -23.055 6.351   -51.625  1.00 27.38  ? 237  LEU D CG  1 
ATOM   12545 C CD1 . LEU D 1 244 ? -24.080 6.358   -50.505  1.00 26.96  ? 237  LEU D CD1 1 
ATOM   12546 C CD2 . LEU D 1 244 ? -22.247 7.646   -51.588  1.00 27.57  ? 237  LEU D CD2 1 
ATOM   12547 N N   . GLU D 1 245 ? -22.302 3.634   -54.361  1.00 20.79  ? 238  GLU D N   1 
ATOM   12548 C CA  . GLU D 1 245 ? -23.240 3.478   -55.495  1.00 20.79  ? 238  GLU D CA  1 
ATOM   12549 C C   . GLU D 1 245 ? -24.613 3.908   -54.994  1.00 19.27  ? 238  GLU D C   1 
ATOM   12550 O O   . GLU D 1 245 ? -24.981 3.550   -53.880  1.00 19.92  ? 238  GLU D O   1 
ATOM   12551 C CB  . GLU D 1 245 ? -23.311 2.018   -55.950  1.00 21.94  ? 238  GLU D CB  1 
ATOM   12552 C CG  . GLU D 1 245 ? -21.987 1.374   -56.313  1.00 21.13  ? 238  GLU D CG  1 
ATOM   12553 C CD  . GLU D 1 245 ? -22.006 -0.147  -56.231  1.00 20.52  ? 238  GLU D CD  1 
ATOM   12554 O OE1 . GLU D 1 245 ? -22.444 -0.799  -57.229  1.00 19.83  ? 238  GLU D OE1 1 
ATOM   12555 O OE2 . GLU D 1 245 ? -21.624 -0.679  -55.158  1.00 18.44  ? 238  GLU D OE2 1 
ATOM   12556 N N   . PRO D 1 246 ? -25.419 4.649   -55.776  1.00 17.99  ? 239  PRO D N   1 
ATOM   12557 C CA  . PRO D 1 246 ? -26.785 4.976   -55.368  1.00 18.93  ? 239  PRO D CA  1 
ATOM   12558 C C   . PRO D 1 246 ? -27.635 3.718   -55.149  1.00 18.44  ? 239  PRO D C   1 
ATOM   12559 O O   . PRO D 1 246 ? -28.552 3.761   -54.354  1.00 18.43  ? 239  PRO D O   1 
ATOM   12560 C CB  . PRO D 1 246 ? -27.370 5.758   -56.558  1.00 19.18  ? 239  PRO D CB  1 
ATOM   12561 C CG  . PRO D 1 246 ? -26.155 6.215   -57.353  1.00 18.67  ? 239  PRO D CG  1 
ATOM   12562 C CD  . PRO D 1 246 ? -25.079 5.178   -57.101  1.00 18.55  ? 239  PRO D CD  1 
ATOM   12563 N N   . ILE D 1 247 ? -27.334 2.671   -55.925  1.00 19.31  ? 240  ILE D N   1 
ATOM   12564 C CA  . ILE D 1 247 ? -27.913 1.298   -55.841  1.00 20.21  ? 240  ILE D CA  1 
ATOM   12565 C C   . ILE D 1 247 ? -26.754 0.351   -56.099  1.00 20.22  ? 240  ILE D C   1 
ATOM   12566 O O   . ILE D 1 247 ? -26.030 0.589   -57.066  1.00 21.40  ? 240  ILE D O   1 
ATOM   12567 C CB  . ILE D 1 247 ? -29.050 1.094   -56.869  1.00 20.39  ? 240  ILE D CB  1 
ATOM   12568 C CG1 . ILE D 1 247 ? -30.196 2.071   -56.609  1.00 20.92  ? 240  ILE D CG1 1 
ATOM   12569 C CG2 . ILE D 1 247 ? -29.554 -0.352  -56.898  1.00 20.50  ? 240  ILE D CG2 1 
ATOM   12570 C CD1 . ILE D 1 247 ? -31.097 2.287   -57.802  1.00 21.44  ? 240  ILE D CD1 1 
ATOM   12571 N N   . GLN D 1 248 ? -26.567 -0.656  -55.263  1.00 20.57  ? 241  GLN D N   1 
ATOM   12572 C CA  . GLN D 1 248 ? -25.416 -1.569  -55.412  1.00 20.72  ? 241  GLN D CA  1 
ATOM   12573 C C   . GLN D 1 248 ? -25.775 -2.570  -56.497  1.00 21.63  ? 241  GLN D C   1 
ATOM   12574 O O   . GLN D 1 248 ? -26.810 -3.234  -56.341  1.00 22.48  ? 241  GLN D O   1 
ATOM   12575 C CB  . GLN D 1 248 ? -25.080 -2.210  -54.071  1.00 21.80  ? 241  GLN D CB  1 
ATOM   12576 C CG  . GLN D 1 248 ? -24.589 -1.184  -53.065  1.00 21.36  ? 241  GLN D CG  1 
ATOM   12577 C CD  . GLN D 1 248 ? -24.074 -1.816  -51.805  1.00 21.43  ? 241  GLN D CD  1 
ATOM   12578 O OE1 . GLN D 1 248 ? -24.534 -2.877  -51.382  1.00 22.24  ? 241  GLN D OE1 1 
ATOM   12579 N NE2 . GLN D 1 248 ? -23.107 -1.147  -51.204  1.00 21.74  ? 241  GLN D NE2 1 
ATOM   12580 N N   . GLY D 1 249 ? -25.011 -2.570  -57.587  1.00 21.89  ? 242  GLY D N   1 
ATOM   12581 C CA  . GLY D 1 249 ? -25.148 -3.541  -58.678  1.00 23.68  ? 242  GLY D CA  1 
ATOM   12582 C C   . GLY D 1 249 ? -24.611 -4.898  -58.268  1.00 26.74  ? 242  GLY D C   1 
ATOM   12583 O O   . GLY D 1 249 ? -25.402 -5.827  -58.106  1.00 26.38  ? 242  GLY D O   1 
ATOM   12584 N N   . GLU D 1 250 ? -23.298 -5.014  -58.081  1.00 32.09  ? 243  GLU D N   1 
ATOM   12585 C CA  . GLU D 1 250 ? -22.630 -6.325  -57.860  1.00 34.37  ? 243  GLU D CA  1 
ATOM   12586 C C   . GLU D 1 250 ? -23.087 -6.878  -56.508  1.00 32.11  ? 243  GLU D C   1 
ATOM   12587 O O   . GLU D 1 250 ? -23.095 -8.117  -56.351  1.00 29.45  ? 243  GLU D O   1 
ATOM   12588 C CB  . GLU D 1 250 ? -21.114 -6.176  -57.988  1.00 38.80  ? 243  GLU D CB  1 
ATOM   12589 C CG  . GLU D 1 250 ? -20.664 -5.602  -59.334  1.00 43.65  ? 243  GLU D CG  1 
ATOM   12590 C CD  . GLU D 1 250 ? -21.202 -6.221  -60.622  1.00 46.51  ? 243  GLU D CD  1 
ATOM   12591 O OE1 . GLU D 1 250 ? -21.403 -7.458  -60.656  1.00 46.34  ? 243  GLU D OE1 1 
ATOM   12592 O OE2 . GLU D 1 250 ? -21.423 -5.456  -61.608  1.00 53.77  ? 243  GLU D OE2 1 
ATOM   12593 N N   . GLY D 1 251 ? -23.502 -5.979  -55.606  1.00 33.89  ? 244  GLY D N   1 
ATOM   12594 C CA  . GLY D 1 251 ? -24.138 -6.298  -54.311  1.00 34.35  ? 244  GLY D CA  1 
ATOM   12595 C C   . GLY D 1 251 ? -25.425 -7.101  -54.473  1.00 34.77  ? 244  GLY D C   1 
ATOM   12596 O O   . GLY D 1 251 ? -25.838 -7.703  -53.473  1.00 39.24  ? 244  GLY D O   1 
ATOM   12597 N N   . GLY D 1 252 ? -26.049 -7.081  -55.662  1.00 34.34  ? 245  GLY D N   1 
ATOM   12598 C CA  . GLY D 1 252 ? -27.260 -7.851  -56.022  1.00 34.62  ? 245  GLY D CA  1 
ATOM   12599 C C   . GLY D 1 252 ? -28.497 -6.966  -56.197  1.00 33.84  ? 245  GLY D C   1 
ATOM   12600 O O   . GLY D 1 252 ? -29.607 -7.447  -55.889  1.00 33.41  ? 245  GLY D O   1 
ATOM   12601 N N   . VAL D 1 253 ? -28.330 -5.736  -56.702  1.00 32.80  ? 246  VAL D N   1 
ATOM   12602 C CA  . VAL D 1 253 ? -29.399 -4.697  -56.854  1.00 32.61  ? 246  VAL D CA  1 
ATOM   12603 C C   . VAL D 1 253 ? -29.987 -4.391  -55.480  1.00 29.07  ? 246  VAL D C   1 
ATOM   12604 O O   . VAL D 1 253 ? -31.107 -4.794  -55.178  1.00 24.98  ? 246  VAL D O   1 
ATOM   12605 C CB  . VAL D 1 253 ? -30.482 -5.103  -57.867  1.00 34.72  ? 246  VAL D CB  1 
ATOM   12606 C CG1 . VAL D 1 253 ? -31.504 -3.993  -58.059  1.00 35.53  ? 246  VAL D CG1 1 
ATOM   12607 C CG2 . VAL D 1 253 ? -29.848 -5.481  -59.199  1.00 38.30  ? 246  VAL D CG2 1 
ATOM   12608 N N   . ILE D 1 254 ? -29.183 -3.728  -54.666  1.00 27.98  ? 247  ILE D N   1 
ATOM   12609 C CA  . ILE D 1 254 ? -29.537 -3.386  -53.269  1.00 26.33  ? 247  ILE D CA  1 
ATOM   12610 C C   . ILE D 1 254 ? -29.988 -1.944  -53.297  1.00 24.06  ? 247  ILE D C   1 
ATOM   12611 O O   . ILE D 1 254 ? -29.168 -1.061  -53.584  1.00 23.77  ? 247  ILE D O   1 
ATOM   12612 C CB  . ILE D 1 254 ? -28.340 -3.586  -52.323  1.00 29.49  ? 247  ILE D CB  1 
ATOM   12613 C CG1 . ILE D 1 254 ? -27.739 -4.993  -52.421  1.00 30.50  ? 247  ILE D CG1 1 
ATOM   12614 C CG2 . ILE D 1 254 ? -28.744 -3.248  -50.906  1.00 28.76  ? 247  ILE D CG2 1 
ATOM   12615 C CD1 . ILE D 1 254 ? -28.771 -6.112  -52.330  1.00 30.50  ? 247  ILE D CD1 1 
ATOM   12616 N N   . LEU D 1 255 ? -31.270 -1.747  -53.059  1.00 23.97  ? 248  LEU D N   1 
ATOM   12617 C CA  . LEU D 1 255 ? -31.890 -0.407  -53.036  1.00 24.77  ? 248  LEU D CA  1 
ATOM   12618 C C   . LEU D 1 255 ? -31.786 0.131   -51.619  1.00 26.76  ? 248  LEU D C   1 
ATOM   12619 O O   . LEU D 1 255 ? -32.194 -0.526  -50.660  1.00 27.12  ? 248  LEU D O   1 
ATOM   12620 C CB  . LEU D 1 255 ? -33.349 -0.512  -53.486  1.00 24.27  ? 248  LEU D CB  1 
ATOM   12621 C CG  . LEU D 1 255 ? -33.602 -0.419  -54.982  1.00 23.24  ? 248  LEU D CG  1 
ATOM   12622 C CD1 . LEU D 1 255 ? -32.864 -1.493  -55.752  1.00 22.41  ? 248  LEU D CD1 1 
ATOM   12623 C CD2 . LEU D 1 255 ? -35.091 -0.516  -55.233  1.00 25.07  ? 248  LEU D CD2 1 
ATOM   12624 N N   . PRO D 1 256 ? -31.274 1.364   -51.457  1.00 28.55  ? 249  PRO D N   1 
ATOM   12625 C CA  . PRO D 1 256 ? -31.232 1.997   -50.140  1.00 28.33  ? 249  PRO D CA  1 
ATOM   12626 C C   . PRO D 1 256 ? -32.643 2.416   -49.734  1.00 28.22  ? 249  PRO D C   1 
ATOM   12627 O O   . PRO D 1 256 ? -33.518 2.526   -50.584  1.00 26.56  ? 249  PRO D O   1 
ATOM   12628 C CB  . PRO D 1 256 ? -30.353 3.220   -50.388  1.00 28.68  ? 249  PRO D CB  1 
ATOM   12629 C CG  . PRO D 1 256 ? -30.622 3.566   -51.831  1.00 30.44  ? 249  PRO D CG  1 
ATOM   12630 C CD  . PRO D 1 256 ? -30.818 2.245   -52.549  1.00 29.95  ? 249  PRO D CD  1 
ATOM   12631 N N   . PRO D 1 257 ? -32.920 2.707   -48.444  1.00 28.81  ? 250  PRO D N   1 
ATOM   12632 C CA  . PRO D 1 257 ? -34.236 3.227   -48.076  1.00 26.28  ? 250  PRO D CA  1 
ATOM   12633 C C   . PRO D 1 257 ? -34.360 4.597   -48.728  1.00 25.07  ? 250  PRO D C   1 
ATOM   12634 O O   . PRO D 1 257 ? -33.374 5.297   -48.966  1.00 23.64  ? 250  PRO D O   1 
ATOM   12635 C CB  . PRO D 1 257 ? -34.243 3.305   -46.545  1.00 26.05  ? 250  PRO D CB  1 
ATOM   12636 C CG  . PRO D 1 257 ? -32.895 2.663   -46.090  1.00 27.21  ? 250  PRO D CG  1 
ATOM   12637 C CD  . PRO D 1 257 ? -31.983 2.638   -47.301  1.00 28.04  ? 250  PRO D CD  1 
ATOM   12638 N N   . PRO D 1 258 ? -35.579 5.016   -49.086  1.00 26.41  ? 251  PRO D N   1 
ATOM   12639 C CA  . PRO D 1 258 ? -35.757 6.310   -49.739  1.00 27.93  ? 251  PRO D CA  1 
ATOM   12640 C C   . PRO D 1 258 ? -35.282 7.443   -48.808  1.00 27.43  ? 251  PRO D C   1 
ATOM   12641 O O   . PRO D 1 258 ? -35.434 7.333   -47.636  1.00 25.58  ? 251  PRO D O   1 
ATOM   12642 C CB  . PRO D 1 258 ? -37.255 6.333   -50.094  1.00 28.09  ? 251  PRO D CB  1 
ATOM   12643 C CG  . PRO D 1 258 ? -37.874 5.318   -49.152  1.00 28.90  ? 251  PRO D CG  1 
ATOM   12644 C CD  . PRO D 1 258 ? -36.819 4.254   -48.938  1.00 28.33  ? 251  PRO D CD  1 
ATOM   12645 N N   . GLY D 1 259 ? -34.682 8.488   -49.379  1.00 28.79  ? 252  GLY D N   1 
ATOM   12646 C CA  . GLY D 1 259 ? -34.106 9.646   -48.658  1.00 28.27  ? 252  GLY D CA  1 
ATOM   12647 C C   . GLY D 1 259 ? -32.671 9.425   -48.182  1.00 26.46  ? 252  GLY D C   1 
ATOM   12648 O O   . GLY D 1 259 ? -32.045 10.424  -47.758  1.00 28.22  ? 252  GLY D O   1 
ATOM   12649 N N   . TYR D 1 260 ? -32.162 8.184   -48.216  1.00 24.02  ? 253  TYR D N   1 
ATOM   12650 C CA  . TYR D 1 260 ? -30.786 7.797   -47.782  1.00 22.44  ? 253  TYR D CA  1 
ATOM   12651 C C   . TYR D 1 260 ? -29.712 8.678   -48.438  1.00 21.35  ? 253  TYR D C   1 
ATOM   12652 O O   . TYR D 1 260 ? -28.843 9.246   -47.784  1.00 20.43  ? 253  TYR D O   1 
ATOM   12653 C CB  . TYR D 1 260 ? -30.495 6.351   -48.173  1.00 22.44  ? 253  TYR D CB  1 
ATOM   12654 C CG  . TYR D 1 260 ? -29.084 5.898   -47.885  1.00 22.73  ? 253  TYR D CG  1 
ATOM   12655 C CD1 . TYR D 1 260 ? -28.602 5.846   -46.589  1.00 22.30  ? 253  TYR D CD1 1 
ATOM   12656 C CD2 . TYR D 1 260 ? -28.244 5.487   -48.903  1.00 23.43  ? 253  TYR D CD2 1 
ATOM   12657 C CE1 . TYR D 1 260 ? -27.314 5.412   -46.311  1.00 22.28  ? 253  TYR D CE1 1 
ATOM   12658 C CE2 . TYR D 1 260 ? -26.953 5.049   -48.648  1.00 23.52  ? 253  TYR D CE2 1 
ATOM   12659 C CZ  . TYR D 1 260 ? -26.483 5.014   -47.345  1.00 22.35  ? 253  TYR D CZ  1 
ATOM   12660 O OH  . TYR D 1 260 ? -25.229 4.557   -47.085  1.00 18.49  ? 253  TYR D OH  1 
ATOM   12661 N N   . LEU D 1 261 ? -29.752 8.751   -49.752  1.00 21.34  ? 254  LEU D N   1 
ATOM   12662 C CA  . LEU D 1 261 ? -28.778 9.530   -50.549  1.00 20.67  ? 254  LEU D CA  1 
ATOM   12663 C C   . LEU D 1 261 ? -28.801 11.001  -50.106  1.00 20.19  ? 254  LEU D C   1 
ATOM   12664 O O   . LEU D 1 261 ? -27.733 11.600  -49.932  1.00 19.36  ? 254  LEU D O   1 
ATOM   12665 C CB  . LEU D 1 261 ? -29.151 9.358   -52.020  1.00 20.58  ? 254  LEU D CB  1 
ATOM   12666 C CG  . LEU D 1 261 ? -28.032 8.971   -52.971  1.00 22.22  ? 254  LEU D CG  1 
ATOM   12667 C CD1 . LEU D 1 261 ? -27.184 7.832   -52.408  1.00 23.41  ? 254  LEU D CD1 1 
ATOM   12668 C CD2 . LEU D 1 261 ? -28.598 8.596   -54.329  1.00 21.32  ? 254  LEU D CD2 1 
ATOM   12669 N N   . THR D 1 262 ? -29.985 11.556  -49.902  1.00 20.69  ? 255  THR D N   1 
ATOM   12670 C CA  . THR D 1 262 ? -30.189 12.964  -49.499  1.00 21.05  ? 255  THR D CA  1 
ATOM   12671 C C   . THR D 1 262 ? -29.530 13.170  -48.145  1.00 22.40  ? 255  THR D C   1 
ATOM   12672 O O   . THR D 1 262 ? -28.902 14.226  -47.953  1.00 23.77  ? 255  THR D O   1 
ATOM   12673 C CB  . THR D 1 262 ? -31.684 13.296  -49.426  1.00 20.93  ? 255  THR D CB  1 
ATOM   12674 O OG1 . THR D 1 262 ? -32.184 13.256  -50.760  1.00 21.00  ? 255  THR D OG1 1 
ATOM   12675 C CG2 . THR D 1 262 ? -31.944 14.645  -48.796  1.00 20.58  ? 255  THR D CG2 1 
ATOM   12676 N N   . ALA D 1 263 ? -29.703 12.192  -47.245  1.00 23.10  ? 256  ALA D N   1 
ATOM   12677 C CA  . ALA D 1 263 ? -29.188 12.217  -45.857  1.00 22.38  ? 256  ALA D CA  1 
ATOM   12678 C C   . ALA D 1 263 ? -27.648 12.143  -45.888  1.00 22.43  ? 256  ALA D C   1 
ATOM   12679 O O   . ALA D 1 263 ? -26.996 12.917  -45.159  1.00 20.29  ? 256  ALA D O   1 
ATOM   12680 C CB  . ALA D 1 263 ? -29.801 11.094  -45.060  1.00 21.67  ? 256  ALA D CB  1 
ATOM   12681 N N   . VAL D 1 264 ? -27.095 11.261  -46.729  1.00 21.99  ? 257  VAL D N   1 
ATOM   12682 C CA  . VAL D 1 264 ? -25.621 11.105  -46.905  1.00 21.08  ? 257  VAL D CA  1 
ATOM   12683 C C   . VAL D 1 264 ? -25.041 12.452  -47.358  1.00 21.01  ? 257  VAL D C   1 
ATOM   12684 O O   . VAL D 1 264 ? -23.968 12.821  -46.859  1.00 23.78  ? 257  VAL D O   1 
ATOM   12685 C CB  . VAL D 1 264 ? -25.277 9.974   -47.890  1.00 19.96  ? 257  VAL D CB  1 
ATOM   12686 C CG1 . VAL D 1 264 ? -23.806 9.999   -48.282  1.00 20.45  ? 257  VAL D CG1 1 
ATOM   12687 C CG2 . VAL D 1 264 ? -25.677 8.603   -47.355  1.00 19.04  ? 257  VAL D CG2 1 
ATOM   12688 N N   . ARG D 1 265 ? -25.742 13.166  -48.232  1.00 21.82  ? 258  ARG D N   1 
ATOM   12689 C CA  . ARG D 1 265 ? -25.321 14.487  -48.759  1.00 22.40  ? 258  ARG D CA  1 
ATOM   12690 C C   . ARG D 1 265 ? -25.289 15.500  -47.619  1.00 23.27  ? 258  ARG D C   1 
ATOM   12691 O O   . ARG D 1 265 ? -24.285 16.207  -47.498  1.00 21.74  ? 258  ARG D O   1 
ATOM   12692 C CB  . ARG D 1 265 ? -26.229 14.942  -49.907  1.00 21.84  ? 258  ARG D CB  1 
ATOM   12693 C CG  . ARG D 1 265 ? -26.103 16.418  -50.272  1.00 22.13  ? 258  ARG D CG  1 
ATOM   12694 C CD  . ARG D 1 265 ? -24.898 16.798  -51.116  1.00 22.21  ? 258  ARG D CD  1 
ATOM   12695 N NE  . ARG D 1 265 ? -23.630 16.901  -50.407  1.00 20.95  ? 258  ARG D NE  1 
ATOM   12696 C CZ  . ARG D 1 265 ? -22.448 17.010  -50.991  1.00 22.33  ? 258  ARG D CZ  1 
ATOM   12697 N NH1 . ARG D 1 265 ? -22.349 17.028  -52.313  1.00 24.73  ? 258  ARG D NH1 1 
ATOM   12698 N NH2 . ARG D 1 265 ? -21.354 17.072  -50.260  1.00 22.44  ? 258  ARG D NH2 1 
ATOM   12699 N N   . LYS D 1 266 ? -26.348 15.594  -46.819  1.00 29.64  ? 259  LYS D N   1 
ATOM   12700 C CA  . LYS D 1 266 ? -26.372 16.526  -45.657  1.00 33.87  ? 259  LYS D CA  1 
ATOM   12701 C C   . LYS D 1 266 ? -25.270 16.138  -44.662  1.00 30.03  ? 259  LYS D C   1 
ATOM   12702 O O   . LYS D 1 266 ? -24.634 17.046  -44.100  1.00 29.89  ? 259  LYS D O   1 
ATOM   12703 C CB  . LYS D 1 266 ? -27.742 16.526  -44.984  1.00 40.99  ? 259  LYS D CB  1 
ATOM   12704 C CG  . LYS D 1 266 ? -28.658 17.652  -45.456  1.00 50.91  ? 259  LYS D CG  1 
ATOM   12705 C CD  . LYS D 1 266 ? -30.115 17.476  -45.082  1.00 58.42  ? 259  LYS D CD  1 
ATOM   12706 C CE  . LYS D 1 266 ? -30.349 17.292  -43.588  1.00 62.61  ? 259  LYS D CE  1 
ATOM   12707 N NZ  . LYS D 1 266 ? -29.627 18.290  -42.759  1.00 60.98  ? 259  LYS D NZ  1 
ATOM   12708 N N   . LEU D 1 267 ? -25.091 14.838  -44.433  1.00 28.36  ? 260  LEU D N   1 
ATOM   12709 C CA  . LEU D 1 267 ? -24.085 14.281  -43.490  1.00 28.05  ? 260  LEU D CA  1 
ATOM   12710 C C   . LEU D 1 267 ? -22.677 14.665  -43.969  1.00 28.05  ? 260  LEU D C   1 
ATOM   12711 O O   . LEU D 1 267 ? -21.920 15.199  -43.180  1.00 28.32  ? 260  LEU D O   1 
ATOM   12712 C CB  . LEU D 1 267 ? -24.278 12.766  -43.444  1.00 29.16  ? 260  LEU D CB  1 
ATOM   12713 C CG  . LEU D 1 267 ? -23.494 12.032  -42.370  1.00 31.82  ? 260  LEU D CG  1 
ATOM   12714 C CD1 . LEU D 1 267 ? -24.166 12.233  -41.023  1.00 35.58  ? 260  LEU D CD1 1 
ATOM   12715 C CD2 . LEU D 1 267 ? -23.385 10.552  -42.703  1.00 31.81  ? 260  LEU D CD2 1 
ATOM   12716 N N   . CYS D 1 268 ? -22.363 14.443  -45.247  1.00 27.83  ? 261  CYS D N   1 
ATOM   12717 C CA  . CYS D 1 268 ? -21.102 14.900  -45.883  1.00 28.74  ? 261  CYS D CA  1 
ATOM   12718 C C   . CYS D 1 268 ? -20.972 16.427  -45.741  1.00 28.47  ? 261  CYS D C   1 
ATOM   12719 O O   . CYS D 1 268 ? -19.891 16.891  -45.383  1.00 28.38  ? 261  CYS D O   1 
ATOM   12720 C CB  . CYS D 1 268 ? -21.033 14.482  -47.350  1.00 30.49  ? 261  CYS D CB  1 
ATOM   12721 S SG  . CYS D 1 268 ? -20.729 12.714  -47.625  1.00 29.25  ? 261  CYS D SG  1 
ATOM   12722 N N   . ASP D 1 269 ? -22.028 17.194  -46.011  1.00 28.45  ? 262  ASP D N   1 
ATOM   12723 C CA  . ASP D 1 269 ? -21.993 18.674  -45.890  1.00 30.54  ? 262  ASP D CA  1 
ATOM   12724 C C   . ASP D 1 269 ? -21.630 19.079  -44.459  1.00 32.90  ? 262  ASP D C   1 
ATOM   12725 O O   . ASP D 1 269 ? -20.883 20.056  -44.299  1.00 40.92  ? 262  ASP D O   1 
ATOM   12726 C CB  . ASP D 1 269 ? -23.335 19.297  -46.254  1.00 31.23  ? 262  ASP D CB  1 
ATOM   12727 C CG  . ASP D 1 269 ? -23.566 19.362  -47.741  1.00 34.90  ? 262  ASP D CG  1 
ATOM   12728 O OD1 . ASP D 1 269 ? -22.558 19.361  -48.477  1.00 36.43  ? 262  ASP D OD1 1 
ATOM   12729 O OD2 . ASP D 1 269 ? -24.753 19.413  -48.148  1.00 38.62  ? 262  ASP D OD2 1 
ATOM   12730 N N   . GLU D 1 270 ? -22.160 18.370  -43.468  1.00 30.59  ? 263  GLU D N   1 
ATOM   12731 C CA  . GLU D 1 270 ? -22.020 18.717  -42.032  1.00 32.95  ? 263  GLU D CA  1 
ATOM   12732 C C   . GLU D 1 270 ? -20.566 18.503  -41.596  1.00 31.54  ? 263  GLU D C   1 
ATOM   12733 O O   . GLU D 1 270 ? -20.034 19.397  -40.919  1.00 36.86  ? 263  GLU D O   1 
ATOM   12734 C CB  . GLU D 1 270 ? -23.001 17.885  -41.196  1.00 35.30  ? 263  GLU D CB  1 
ATOM   12735 C CG  . GLU D 1 270 ? -22.774 17.988  -39.697  1.00 39.93  ? 263  GLU D CG  1 
ATOM   12736 C CD  . GLU D 1 270 ? -23.797 17.248  -38.843  1.00 43.17  ? 263  GLU D CD  1 
ATOM   12737 O OE1 . GLU D 1 270 ? -24.946 17.080  -39.311  1.00 46.43  ? 263  GLU D OE1 1 
ATOM   12738 O OE2 . GLU D 1 270 ? -23.448 16.830  -37.718  1.00 46.72  ? 263  GLU D OE2 1 
ATOM   12739 N N   . PHE D 1 271 ? -19.957 17.372  -41.967  1.00 28.64  ? 264  PHE D N   1 
ATOM   12740 C CA  . PHE D 1 271 ? -18.595 16.948  -41.544  1.00 27.63  ? 264  PHE D CA  1 
ATOM   12741 C C   . PHE D 1 271 ? -17.508 17.525  -42.466  1.00 26.62  ? 264  PHE D C   1 
ATOM   12742 O O   . PHE D 1 271 ? -16.341 17.334  -42.158  1.00 24.87  ? 264  PHE D O   1 
ATOM   12743 C CB  . PHE D 1 271 ? -18.520 15.420  -41.477  1.00 27.88  ? 264  PHE D CB  1 
ATOM   12744 C CG  . PHE D 1 271 ? -19.135 14.857  -40.224  1.00 28.26  ? 264  PHE D CG  1 
ATOM   12745 C CD1 . PHE D 1 271 ? -20.492 14.613  -40.150  1.00 30.38  ? 264  PHE D CD1 1 
ATOM   12746 C CD2 . PHE D 1 271 ? -18.364 14.606  -39.101  1.00 29.66  ? 264  PHE D CD2 1 
ATOM   12747 C CE1 . PHE D 1 271 ? -21.065 14.134  -38.976  1.00 31.62  ? 264  PHE D CE1 1 
ATOM   12748 C CE2 . PHE D 1 271 ? -18.935 14.119  -37.934  1.00 29.80  ? 264  PHE D CE2 1 
ATOM   12749 C CZ  . PHE D 1 271 ? -20.289 13.886  -37.875  1.00 28.43  ? 264  PHE D CZ  1 
ATOM   12750 N N   . GLY D 1 272 ? -17.885 18.212  -43.550  1.00 27.62  ? 265  GLY D N   1 
ATOM   12751 C CA  . GLY D 1 272 ? -16.956 18.751  -44.569  1.00 27.53  ? 265  GLY D CA  1 
ATOM   12752 C C   . GLY D 1 272 ? -16.257 17.656  -45.369  1.00 27.07  ? 265  GLY D C   1 
ATOM   12753 O O   . GLY D 1 272 ? -15.112 17.881  -45.791  1.00 29.59  ? 265  GLY D O   1 
ATOM   12754 N N   . ALA D 1 273 ? -16.907 16.504  -45.568  1.00 25.68  ? 266  ALA D N   1 
ATOM   12755 C CA  . ALA D 1 273 ? -16.431 15.378  -46.412  1.00 25.28  ? 266  ALA D CA  1 
ATOM   12756 C C   . ALA D 1 273 ? -16.990 15.533  -47.829  1.00 25.25  ? 266  ALA D C   1 
ATOM   12757 O O   . ALA D 1 273 ? -18.126 16.049  -47.969  1.00 26.79  ? 266  ALA D O   1 
ATOM   12758 C CB  . ALA D 1 273 ? -16.846 14.053  -45.821  1.00 24.17  ? 266  ALA D CB  1 
ATOM   12759 N N   . LEU D 1 274 ? -16.233 15.099  -48.842  1.00 24.68  ? 267  LEU D N   1 
ATOM   12760 C CA  . LEU D 1 274 ? -16.714 15.122  -50.248  1.00 23.89  ? 267  LEU D CA  1 
ATOM   12761 C C   . LEU D 1 274 ? -17.585 13.893  -50.493  1.00 23.59  ? 267  LEU D C   1 
ATOM   12762 O O   . LEU D 1 274 ? -17.290 12.796  -49.977  1.00 23.06  ? 267  LEU D O   1 
ATOM   12763 C CB  . LEU D 1 274 ? -15.543 15.171  -51.226  1.00 23.97  ? 267  LEU D CB  1 
ATOM   12764 C CG  . LEU D 1 274 ? -14.648 16.406  -51.124  1.00 25.03  ? 267  LEU D CG  1 
ATOM   12765 C CD1 . LEU D 1 274 ? -13.514 16.320  -52.143  1.00 26.18  ? 267  LEU D CD1 1 
ATOM   12766 C CD2 . LEU D 1 274 ? -15.446 17.695  -51.273  1.00 24.43  ? 267  LEU D CD2 1 
ATOM   12767 N N   . MET D 1 275 ? -18.656 14.102  -51.249  1.00 24.07  ? 268  MET D N   1 
ATOM   12768 C CA  . MET D 1 275 ? -19.571 13.016  -51.655  1.00 24.20  ? 268  MET D CA  1 
ATOM   12769 C C   . MET D 1 275 ? -19.182 12.541  -53.064  1.00 22.47  ? 268  MET D C   1 
ATOM   12770 O O   . MET D 1 275 ? -19.249 13.333  -54.016  1.00 19.82  ? 268  MET D O   1 
ATOM   12771 C CB  . MET D 1 275 ? -21.021 13.489  -51.622  1.00 24.08  ? 268  MET D CB  1 
ATOM   12772 C CG  . MET D 1 275 ? -21.979 12.397  -51.987  1.00 25.12  ? 268  MET D CG  1 
ATOM   12773 S SD  . MET D 1 275 ? -23.693 12.805  -51.573  1.00 24.05  ? 268  MET D SD  1 
ATOM   12774 C CE  . MET D 1 275 ? -24.485 11.268  -52.032  1.00 25.32  ? 268  MET D CE  1 
ATOM   12775 N N   . ILE D 1 276 ? -18.768 11.284  -53.160  1.00 21.55  ? 269  ILE D N   1 
ATOM   12776 C CA  . ILE D 1 276 ? -18.460 10.618  -54.448  1.00 20.98  ? 269  ILE D CA  1 
ATOM   12777 C C   . ILE D 1 276 ? -19.584 9.635   -54.749  1.00 21.27  ? 269  ILE D C   1 
ATOM   12778 O O   . ILE D 1 276 ? -19.749 8.672   -53.969  1.00 21.01  ? 269  ILE D O   1 
ATOM   12779 C CB  . ILE D 1 276 ? -17.104 9.901   -54.392  1.00 20.68  ? 269  ILE D CB  1 
ATOM   12780 C CG1 . ILE D 1 276 ? -15.983 10.872  -54.035  1.00 20.28  ? 269  ILE D CG1 1 
ATOM   12781 C CG2 . ILE D 1 276 ? -16.832 9.194   -55.710  1.00 20.68  ? 269  ILE D CG2 1 
ATOM   12782 C CD1 . ILE D 1 276 ? -14.626 10.206  -53.941  1.00 20.95  ? 269  ILE D CD1 1 
ATOM   12783 N N   . LEU D 1 277 ? -20.278 9.841   -55.871  1.00 21.77  ? 270  LEU D N   1 
ATOM   12784 C CA  . LEU D 1 277 ? -21.280 8.883   -56.380  1.00 22.07  ? 270  LEU D CA  1 
ATOM   12785 C C   . LEU D 1 277 ? -20.692 8.091   -57.541  1.00 20.75  ? 270  LEU D C   1 
ATOM   12786 O O   . LEU D 1 277 ? -20.359 8.708   -58.554  1.00 18.32  ? 270  LEU D O   1 
ATOM   12787 C CB  . LEU D 1 277 ? -22.530 9.648   -56.814  1.00 25.33  ? 270  LEU D CB  1 
ATOM   12788 C CG  . LEU D 1 277 ? -23.646 9.674   -55.786  1.00 27.88  ? 270  LEU D CG  1 
ATOM   12789 C CD1 . LEU D 1 277 ? -24.927 10.091  -56.477  1.00 29.45  ? 270  LEU D CD1 1 
ATOM   12790 C CD2 . LEU D 1 277 ? -23.831 8.311   -55.116  1.00 28.02  ? 270  LEU D CD2 1 
ATOM   12791 N N   . ASP D 1 278 ? -20.636 6.773   -57.374  1.00 21.36  ? 271  ASP D N   1 
ATOM   12792 C CA  . ASP D 1 278 ? -20.239 5.784   -58.409  1.00 23.21  ? 271  ASP D CA  1 
ATOM   12793 C C   . ASP D 1 278 ? -21.478 5.382   -59.221  1.00 23.36  ? 271  ASP D C   1 
ATOM   12794 O O   . ASP D 1 278 ? -22.161 4.396   -58.846  1.00 23.27  ? 271  ASP D O   1 
ATOM   12795 C CB  . ASP D 1 278 ? -19.567 4.581   -57.742  1.00 25.37  ? 271  ASP D CB  1 
ATOM   12796 C CG  . ASP D 1 278 ? -19.073 3.529   -58.716  1.00 26.25  ? 271  ASP D CG  1 
ATOM   12797 O OD1 . ASP D 1 278 ? -19.397 3.653   -59.898  1.00 25.08  ? 271  ASP D OD1 1 
ATOM   12798 O OD2 . ASP D 1 278 ? -18.355 2.600   -58.263  1.00 29.76  ? 271  ASP D OD2 1 
ATOM   12799 N N   . GLU D 1 279 ? -21.753 6.111   -60.305  1.00 25.15  ? 272  GLU D N   1 
ATOM   12800 C CA  . GLU D 1 279 ? -22.884 5.831   -61.233  1.00 24.53  ? 272  GLU D CA  1 
ATOM   12801 C C   . GLU D 1 279 ? -22.366 5.123   -62.481  1.00 22.41  ? 272  GLU D C   1 
ATOM   12802 O O   . GLU D 1 279 ? -23.018 5.191   -63.526  1.00 19.66  ? 272  GLU D O   1 
ATOM   12803 C CB  . GLU D 1 279 ? -23.614 7.123   -61.588  1.00 25.70  ? 272  GLU D CB  1 
ATOM   12804 C CG  . GLU D 1 279 ? -24.442 7.614   -60.432  1.00 27.21  ? 272  GLU D CG  1 
ATOM   12805 C CD  . GLU D 1 279 ? -25.909 7.843   -60.732  1.00 28.73  ? 272  GLU D CD  1 
ATOM   12806 O OE1 . GLU D 1 279 ? -26.468 7.159   -61.641  1.00 30.90  ? 272  GLU D OE1 1 
ATOM   12807 O OE2 . GLU D 1 279 ? -26.492 8.706   -60.040  1.00 30.65  ? 272  GLU D OE2 1 
ATOM   12808 N N   . VAL D 1 280 ? -21.220 4.466   -62.367  1.00 22.02  ? 273  VAL D N   1 
ATOM   12809 C CA  . VAL D 1 280 ? -20.670 3.617   -63.449  1.00 22.29  ? 273  VAL D CA  1 
ATOM   12810 C C   . VAL D 1 280 ? -21.777 2.674   -63.929  1.00 23.12  ? 273  VAL D C   1 
ATOM   12811 O O   . VAL D 1 280 ? -21.896 2.499   -65.165  1.00 22.31  ? 273  VAL D O   1 
ATOM   12812 C CB  . VAL D 1 280 ? -19.431 2.859   -62.966  1.00 21.28  ? 273  VAL D CB  1 
ATOM   12813 C CG1 . VAL D 1 280 ? -19.093 1.702   -63.880  1.00 21.36  ? 273  VAL D CG1 1 
ATOM   12814 C CG2 . VAL D 1 280 ? -18.259 3.804   -62.812  1.00 21.97  ? 273  VAL D CG2 1 
ATOM   12815 N N   . GLN D 1 281 ? -22.541 2.078   -63.019  1.00 24.98  ? 274  GLN D N   1 
ATOM   12816 C CA  . GLN D 1 281 ? -23.515 1.038   -63.425  1.00 28.26  ? 274  GLN D CA  1 
ATOM   12817 C C   . GLN D 1 281 ? -24.965 1.541   -63.404  1.00 26.92  ? 274  GLN D C   1 
ATOM   12818 O O   . GLN D 1 281 ? -25.767 0.978   -64.178  1.00 25.64  ? 274  GLN D O   1 
ATOM   12819 C CB  . GLN D 1 281 ? -23.380 -0.216  -62.590  1.00 32.55  ? 274  GLN D CB  1 
ATOM   12820 C CG  . GLN D 1 281 ? -24.109 -1.364  -63.253  1.00 34.76  ? 274  GLN D CG  1 
ATOM   12821 C CD  . GLN D 1 281 ? -23.772 -2.690  -62.627  1.00 39.82  ? 274  GLN D CD  1 
ATOM   12822 O OE1 . GLN D 1 281 ? -24.495 -3.663  -62.806  1.00 42.81  ? 274  GLN D OE1 1 
ATOM   12823 N NE2 . GLN D 1 281 ? -22.685 -2.737  -61.870  1.00 39.01  ? 274  GLN D NE2 1 
ATOM   12824 N N   . THR D 1 282 ? -25.274 2.601   -62.661  1.00 25.36  ? 275  THR D N   1 
ATOM   12825 C CA  . THR D 1 282 ? -26.643 3.181   -62.588  1.00 25.59  ? 275  THR D CA  1 
ATOM   12826 C C   . THR D 1 282 ? -26.815 4.374   -63.539  1.00 25.19  ? 275  THR D C   1 
ATOM   12827 O O   . THR D 1 282 ? -27.913 4.927   -63.588  1.00 26.57  ? 275  THR D O   1 
ATOM   12828 C CB  . THR D 1 282 ? -26.950 3.620   -61.160  1.00 26.65  ? 275  THR D CB  1 
ATOM   12829 O OG1 . THR D 1 282 ? -26.021 4.648   -60.818  1.00 27.24  ? 275  THR D OG1 1 
ATOM   12830 C CG2 . THR D 1 282 ? -26.822 2.482   -60.175  1.00 28.52  ? 275  THR D CG2 1 
ATOM   12831 N N   . GLY D 1 283 ? -25.786 4.762   -64.276  1.00 23.64  ? 276  GLY D N   1 
ATOM   12832 C CA  . GLY D 1 283 ? -25.810 5.978   -65.110  1.00 24.36  ? 276  GLY D CA  1 
ATOM   12833 C C   . GLY D 1 283 ? -26.323 5.722   -66.524  1.00 24.98  ? 276  GLY D C   1 
ATOM   12834 O O   . GLY D 1 283 ? -26.580 4.541   -66.906  1.00 25.56  ? 276  GLY D O   1 
ATOM   12835 N N   . MET D 1 284 ? -26.484 6.804   -67.283  1.00 23.14  ? 277  MET D N   1 
ATOM   12836 C CA  . MET D 1 284 ? -26.946 6.773   -68.691  1.00 22.65  ? 277  MET D CA  1 
ATOM   12837 C C   . MET D 1 284 ? -28.330 6.096   -68.786  1.00 23.07  ? 277  MET D C   1 
ATOM   12838 O O   . MET D 1 284 ? -28.515 5.234   -69.676  1.00 22.33  ? 277  MET D O   1 
ATOM   12839 C CB  . MET D 1 284 ? -25.911 6.055   -69.560  1.00 22.64  ? 277  MET D CB  1 
ATOM   12840 C CG  . MET D 1 284 ? -24.478 6.573   -69.366  1.00 22.95  ? 277  MET D CG  1 
ATOM   12841 S SD  . MET D 1 284 ? -24.280 8.357   -68.996  1.00 21.81  ? 277  MET D SD  1 
ATOM   12842 C CE  . MET D 1 284 ? -24.878 9.110   -70.508  1.00 21.93  ? 277  MET D CE  1 
ATOM   12843 N N   . GLY D 1 285 ? -29.264 6.476   -67.901  1.00 21.28  ? 278  GLY D N   1 
ATOM   12844 C CA  . GLY D 1 285 ? -30.704 6.212   -68.049  1.00 20.49  ? 278  GLY D CA  1 
ATOM   12845 C C   . GLY D 1 285 ? -31.160 4.883   -67.464  1.00 20.96  ? 278  GLY D C   1 
ATOM   12846 O O   . GLY D 1 285 ? -32.389 4.650   -67.452  1.00 20.10  ? 278  GLY D O   1 
ATOM   12847 N N   . ARG D 1 286 ? -30.250 4.020   -66.995  1.00 21.94  ? 279  ARG D N   1 
ATOM   12848 C CA  . ARG D 1 286 ? -30.596 2.599   -66.669  1.00 22.21  ? 279  ARG D CA  1 
ATOM   12849 C C   . ARG D 1 286 ? -31.685 2.483   -65.571  1.00 21.26  ? 279  ARG D C   1 
ATOM   12850 O O   . ARG D 1 286 ? -32.440 1.494   -65.607  1.00 18.24  ? 279  ARG D O   1 
ATOM   12851 C CB  . ARG D 1 286 ? -29.357 1.784   -66.279  1.00 22.51  ? 279  ARG D CB  1 
ATOM   12852 C CG  . ARG D 1 286 ? -29.746 0.401   -65.781  1.00 22.93  ? 279  ARG D CG  1 
ATOM   12853 C CD  . ARG D 1 286 ? -28.732 -0.672  -66.057  1.00 23.19  ? 279  ARG D CD  1 
ATOM   12854 N NE  . ARG D 1 286 ? -28.435 -0.824  -67.471  1.00 23.24  ? 279  ARG D NE  1 
ATOM   12855 C CZ  . ARG D 1 286 ? -29.101 -1.602  -68.316  1.00 22.82  ? 279  ARG D CZ  1 
ATOM   12856 N NH1 . ARG D 1 286 ? -30.161 -2.295  -67.912  1.00 21.62  ? 279  ARG D NH1 1 
ATOM   12857 N NH2 . ARG D 1 286 ? -28.694 -1.664  -69.572  1.00 21.80  ? 279  ARG D NH2 1 
ATOM   12858 N N   . THR D 1 287 ? -31.766 3.408   -64.610  1.00 22.29  ? 280  THR D N   1 
ATOM   12859 C CA  . THR D 1 287 ? -32.687 3.284   -63.448  1.00 24.15  ? 280  THR D CA  1 
ATOM   12860 C C   . THR D 1 287 ? -33.990 4.034   -63.701  1.00 24.81  ? 280  THR D C   1 
ATOM   12861 O O   . THR D 1 287 ? -34.834 4.049   -62.789  1.00 23.31  ? 280  THR D O   1 
ATOM   12862 C CB  . THR D 1 287 ? -32.072 3.815   -62.152  1.00 25.53  ? 280  THR D CB  1 
ATOM   12863 O OG1 . THR D 1 287 ? -31.864 5.224   -62.266  1.00 26.92  ? 280  THR D OG1 1 
ATOM   12864 C CG2 . THR D 1 287 ? -30.793 3.093   -61.813  1.00 25.40  ? 280  THR D CG2 1 
ATOM   12865 N N   . GLY D 1 288 ? -34.143 4.642   -64.877  1.00 25.02  ? 281  GLY D N   1 
ATOM   12866 C CA  . GLY D 1 288 ? -35.354 5.409   -65.213  1.00 25.25  ? 281  GLY D CA  1 
ATOM   12867 C C   . GLY D 1 288 ? -35.079 6.897   -65.240  1.00 25.40  ? 281  GLY D C   1 
ATOM   12868 O O   . GLY D 1 288 ? -35.961 7.641   -65.659  1.00 26.45  ? 281  GLY D O   1 
ATOM   12869 N N   . LYS D 1 289 ? -33.896 7.325   -64.820  1.00 27.20  ? 282  LYS D N   1 
ATOM   12870 C CA  . LYS D 1 289 ? -33.417 8.710   -65.053  1.00 28.56  ? 282  LYS D CA  1 
ATOM   12871 C C   . LYS D 1 289 ? -32.007 8.613   -65.631  1.00 27.86  ? 282  LYS D C   1 
ATOM   12872 O O   . LYS D 1 289 ? -31.406 7.517   -65.564  1.00 26.39  ? 282  LYS D O   1 
ATOM   12873 C CB  . LYS D 1 289 ? -33.390 9.536   -63.769  1.00 33.64  ? 282  LYS D CB  1 
ATOM   12874 C CG  . LYS D 1 289 ? -34.680 9.564   -62.965  1.00 37.95  ? 282  LYS D CG  1 
ATOM   12875 C CD  . LYS D 1 289 ? -35.596 10.738  -63.257  1.00 40.85  ? 282  LYS D CD  1 
ATOM   12876 C CE  . LYS D 1 289 ? -36.951 10.596  -62.583  1.00 43.35  ? 282  LYS D CE  1 
ATOM   12877 N NZ  . LYS D 1 289 ? -38.102 10.598  -63.541  1.00 44.09  ? 282  LYS D NZ  1 
ATOM   12878 N N   . MET D 1 290 ? -31.502 9.717   -66.175  1.00 25.62  ? 283  MET D N   1 
ATOM   12879 C CA  . MET D 1 290 ? -30.158 9.768   -66.786  1.00 25.64  ? 283  MET D CA  1 
ATOM   12880 C C   . MET D 1 290 ? -29.139 9.326   -65.719  1.00 25.26  ? 283  MET D C   1 
ATOM   12881 O O   . MET D 1 290 ? -28.260 8.519   -66.055  1.00 24.68  ? 283  MET D O   1 
ATOM   12882 C CB  . MET D 1 290 ? -29.847 11.174  -67.312  1.00 25.98  ? 283  MET D CB  1 
ATOM   12883 C CG  . MET D 1 290 ? -28.546 11.270  -68.089  1.00 24.80  ? 283  MET D CG  1 
ATOM   12884 S SD  . MET D 1 290 ? -28.518 10.069  -69.426  1.00 25.52  ? 283  MET D SD  1 
ATOM   12885 C CE  . MET D 1 290 ? -29.579 10.852  -70.641  1.00 24.93  ? 283  MET D CE  1 
ATOM   12886 N N   . PHE D 1 291 ? -29.294 9.782   -64.474  1.00 23.20  ? 284  PHE D N   1 
ATOM   12887 C CA  . PHE D 1 291 ? -28.493 9.330   -63.307  1.00 23.04  ? 284  PHE D CA  1 
ATOM   12888 C C   . PHE D 1 291 ? -29.429 9.004   -62.133  1.00 21.96  ? 284  PHE D C   1 
ATOM   12889 O O   . PHE D 1 291 ? -30.423 9.710   -61.923  1.00 24.22  ? 284  PHE D O   1 
ATOM   12890 C CB  . PHE D 1 291 ? -27.496 10.415  -62.901  1.00 23.36  ? 284  PHE D CB  1 
ATOM   12891 C CG  . PHE D 1 291 ? -26.772 11.059  -64.050  1.00 23.91  ? 284  PHE D CG  1 
ATOM   12892 C CD1 . PHE D 1 291 ? -25.880 10.328  -64.821  1.00 23.25  ? 284  PHE D CD1 1 
ATOM   12893 C CD2 . PHE D 1 291 ? -26.987 12.395  -64.361  1.00 24.97  ? 284  PHE D CD2 1 
ATOM   12894 C CE1 . PHE D 1 291 ? -25.232 10.924  -65.887  1.00 23.19  ? 284  PHE D CE1 1 
ATOM   12895 C CE2 . PHE D 1 291 ? -26.319 12.994  -65.421  1.00 24.48  ? 284  PHE D CE2 1 
ATOM   12896 C CZ  . PHE D 1 291 ? -25.443 12.254  -66.174  1.00 23.71  ? 284  PHE D CZ  1 
ATOM   12897 N N   . ALA D 1 292 ? -29.124 7.960   -61.378  1.00 20.27  ? 285  ALA D N   1 
ATOM   12898 C CA  . ALA D 1 292 ? -29.920 7.555   -60.202  1.00 20.59  ? 285  ALA D CA  1 
ATOM   12899 C C   . ALA D 1 292 ? -29.935 8.666   -59.143  1.00 20.30  ? 285  ALA D C   1 
ATOM   12900 O O   . ALA D 1 292 ? -30.867 8.673   -58.369  1.00 20.22  ? 285  ALA D O   1 
ATOM   12901 C CB  . ALA D 1 292 ? -29.410 6.257   -59.644  1.00 20.01  ? 285  ALA D CB  1 
ATOM   12902 N N   . CYS D 1 293 ? -28.976 9.592   -59.126  1.00 23.61  ? 286  CYS D N   1 
ATOM   12903 C CA  . CYS D 1 293 ? -28.940 10.722  -58.153  1.00 25.83  ? 286  CYS D CA  1 
ATOM   12904 C C   . CYS D 1 293 ? -30.060 11.719  -58.468  1.00 27.68  ? 286  CYS D C   1 
ATOM   12905 O O   . CYS D 1 293 ? -30.374 12.543  -57.607  1.00 27.05  ? 286  CYS D O   1 
ATOM   12906 C CB  . CYS D 1 293 ? -27.585 11.420  -58.105  1.00 26.77  ? 286  CYS D CB  1 
ATOM   12907 S SG  . CYS D 1 293 ? -27.094 12.331  -59.597  1.00 32.95  ? 286  CYS D SG  1 
ATOM   12908 N N   . GLU D 1 294 ? -30.686 11.623  -59.637  1.00 32.57  ? 287  GLU D N   1 
ATOM   12909 C CA  . GLU D 1 294 ? -31.794 12.531  -60.044  1.00 35.60  ? 287  GLU D CA  1 
ATOM   12910 C C   . GLU D 1 294 ? -33.114 12.121  -59.376  1.00 32.81  ? 287  GLU D C   1 
ATOM   12911 O O   . GLU D 1 294 ? -33.955 13.018  -59.227  1.00 33.87  ? 287  GLU D O   1 
ATOM   12912 C CB  . GLU D 1 294 ? -31.926 12.581  -61.563  1.00 38.19  ? 287  GLU D CB  1 
ATOM   12913 C CG  . GLU D 1 294 ? -30.728 13.238  -62.223  1.00 40.83  ? 287  GLU D CG  1 
ATOM   12914 C CD  . GLU D 1 294 ? -30.783 13.311  -63.741  1.00 43.04  ? 287  GLU D CD  1 
ATOM   12915 O OE1 . GLU D 1 294 ? -31.512 12.511  -64.367  1.00 44.76  ? 287  GLU D OE1 1 
ATOM   12916 O OE2 . GLU D 1 294 ? -30.068 14.163  -64.296  1.00 48.73  ? 287  GLU D OE2 1 
ATOM   12917 N N   . HIS D 1 295 ? -33.286 10.857  -58.970  1.00 29.38  ? 288  HIS D N   1 
ATOM   12918 C CA  . HIS D 1 295 ? -34.493 10.380  -58.241  1.00 31.22  ? 288  HIS D CA  1 
ATOM   12919 C C   . HIS D 1 295 ? -34.744 11.278  -57.022  1.00 33.89  ? 288  HIS D C   1 
ATOM   12920 O O   . HIS D 1 295 ? -35.905 11.648  -56.791  1.00 30.04  ? 288  HIS D O   1 
ATOM   12921 C CB  . HIS D 1 295 ? -34.382 8.904   -57.832  1.00 31.00  ? 288  HIS D CB  1 
ATOM   12922 C CG  . HIS D 1 295 ? -34.405 7.972   -58.991  1.00 31.81  ? 288  HIS D CG  1 
ATOM   12923 N ND1 . HIS D 1 295 ? -35.514 7.848   -59.814  1.00 32.72  ? 288  HIS D ND1 1 
ATOM   12924 C CD2 . HIS D 1 295 ? -33.465 7.141   -59.491  1.00 31.85  ? 288  HIS D CD2 1 
ATOM   12925 C CE1 . HIS D 1 295 ? -35.261 6.970   -60.761  1.00 32.85  ? 288  HIS D CE1 1 
ATOM   12926 N NE2 . HIS D 1 295 ? -33.999 6.525   -60.590  1.00 32.55  ? 288  HIS D NE2 1 
ATOM   12927 N N   . GLU D 1 296 ? -33.684 11.633  -56.283  1.00 34.17  ? 289  GLU D N   1 
ATOM   12928 C CA  . GLU D 1 296 ? -33.778 12.442  -55.045  1.00 36.18  ? 289  GLU D CA  1 
ATOM   12929 C C   . GLU D 1 296 ? -33.254 13.867  -55.272  1.00 35.62  ? 289  GLU D C   1 
ATOM   12930 O O   . GLU D 1 296 ? -33.232 14.648  -54.302  1.00 37.92  ? 289  GLU D O   1 
ATOM   12931 C CB  . GLU D 1 296 ? -33.001 11.740  -53.933  1.00 39.26  ? 289  GLU D CB  1 
ATOM   12932 C CG  . GLU D 1 296 ? -33.720 10.534  -53.339  1.00 41.78  ? 289  GLU D CG  1 
ATOM   12933 C CD  . GLU D 1 296 ? -33.070 9.963   -52.091  1.00 45.92  ? 289  GLU D CD  1 
ATOM   12934 O OE1 . GLU D 1 296 ? -32.331 10.698  -51.388  1.00 40.44  ? 289  GLU D OE1 1 
ATOM   12935 O OE2 . GLU D 1 296 ? -33.309 8.781   -51.809  1.00 54.57  ? 289  GLU D OE2 1 
ATOM   12936 N N   . ASN D 1 297 ? -32.858 14.209  -56.491  1.00 35.54  ? 290  ASN D N   1 
ATOM   12937 C CA  . ASN D 1 297 ? -32.202 15.503  -56.816  1.00 41.28  ? 290  ASN D CA  1 
ATOM   12938 C C   . ASN D 1 297 ? -30.999 15.726  -55.880  1.00 38.07  ? 290  ASN D C   1 
ATOM   12939 O O   . ASN D 1 297 ? -30.893 16.810  -55.253  1.00 37.73  ? 290  ASN D O   1 
ATOM   12940 C CB  . ASN D 1 297 ? -33.201 16.661  -56.762  1.00 47.56  ? 290  ASN D CB  1 
ATOM   12941 C CG  . ASN D 1 297 ? -32.731 17.857  -57.573  1.00 56.17  ? 290  ASN D CG  1 
ATOM   12942 O OD1 . ASN D 1 297 ? -31.893 17.721  -58.473  1.00 58.64  ? 290  ASN D OD1 1 
ATOM   12943 N ND2 . ASN D 1 297 ? -33.249 19.036  -57.256  1.00 61.50  ? 290  ASN D ND2 1 
ATOM   12944 N N   . VAL D 1 298 ? -30.128 14.724  -55.778  1.00 33.40  ? 291  VAL D N   1 
ATOM   12945 C CA  . VAL D 1 298 ? -28.851 14.772  -54.995  1.00 31.23  ? 291  VAL D CA  1 
ATOM   12946 C C   . VAL D 1 298 ? -27.707 15.169  -55.937  1.00 29.00  ? 291  VAL D C   1 
ATOM   12947 O O   . VAL D 1 298 ? -27.533 14.522  -56.978  1.00 25.08  ? 291  VAL D O   1 
ATOM   12948 C CB  . VAL D 1 298 ? -28.576 13.427  -54.298  1.00 30.84  ? 291  VAL D CB  1 
ATOM   12949 C CG1 . VAL D 1 298 ? -27.153 13.327  -53.786  1.00 34.34  ? 291  VAL D CG1 1 
ATOM   12950 C CG2 . VAL D 1 298 ? -29.553 13.179  -53.167  1.00 32.38  ? 291  VAL D CG2 1 
ATOM   12951 N N   . GLN D 1 299 ? -26.978 16.223  -55.587  1.00 29.23  ? 292  GLN D N   1 
ATOM   12952 C CA  . GLN D 1 299 ? -25.735 16.646  -56.271  1.00 32.46  ? 292  GLN D CA  1 
ATOM   12953 C C   . GLN D 1 299 ? -24.525 16.167  -55.461  1.00 28.91  ? 292  GLN D C   1 
ATOM   12954 O O   . GLN D 1 299 ? -24.222 16.719  -54.406  1.00 25.78  ? 292  GLN D O   1 
ATOM   12955 C CB  . GLN D 1 299 ? -25.757 18.165  -56.442  1.00 38.22  ? 292  GLN D CB  1 
ATOM   12956 C CG  . GLN D 1 299 ? -24.712 18.672  -57.428  1.00 41.93  ? 292  GLN D CG  1 
ATOM   12957 C CD  . GLN D 1 299 ? -23.916 19.845  -56.908  1.00 48.45  ? 292  GLN D CD  1 
ATOM   12958 O OE1 . GLN D 1 299 ? -24.396 20.979  -56.892  1.00 59.20  ? 292  GLN D OE1 1 
ATOM   12959 N NE2 . GLN D 1 299 ? -22.681 19.583  -56.499  1.00 50.55  ? 292  GLN D NE2 1 
ATOM   12960 N N   . PRO D 1 300 ? -23.777 15.138  -55.925  1.00 28.29  ? 293  PRO D N   1 
ATOM   12961 C CA  . PRO D 1 300 ? -22.506 14.773  -55.306  1.00 26.83  ? 293  PRO D CA  1 
ATOM   12962 C C   . PRO D 1 300 ? -21.446 15.809  -55.701  1.00 26.67  ? 293  PRO D C   1 
ATOM   12963 O O   . PRO D 1 300 ? -21.691 16.609  -56.569  1.00 27.35  ? 293  PRO D O   1 
ATOM   12964 C CB  . PRO D 1 300 ? -22.207 13.390  -55.888  1.00 25.12  ? 293  PRO D CB  1 
ATOM   12965 C CG  . PRO D 1 300 ? -22.776 13.490  -57.269  1.00 25.60  ? 293  PRO D CG  1 
ATOM   12966 C CD  . PRO D 1 300 ? -24.049 14.313  -57.114  1.00 27.66  ? 293  PRO D CD  1 
ATOM   12967 N N   . ASP D 1 301 ? -20.307 15.794  -55.019  1.00 27.78  ? 294  ASP D N   1 
ATOM   12968 C CA  . ASP D 1 301 ? -19.140 16.666  -55.327  1.00 26.88  ? 294  ASP D CA  1 
ATOM   12969 C C   . ASP D 1 301 ? -18.457 16.119  -56.571  1.00 25.58  ? 294  ASP D C   1 
ATOM   12970 O O   . ASP D 1 301 ? -17.959 16.919  -57.369  1.00 26.00  ? 294  ASP D O   1 
ATOM   12971 C CB  . ASP D 1 301 ? -18.181 16.730  -54.144  1.00 27.33  ? 294  ASP D CB  1 
ATOM   12972 C CG  . ASP D 1 301 ? -18.842 17.412  -52.961  1.00 29.87  ? 294  ASP D CG  1 
ATOM   12973 O OD1 . ASP D 1 301 ? -19.202 18.610  -53.116  1.00 32.45  ? 294  ASP D OD1 1 
ATOM   12974 O OD2 . ASP D 1 301 ? -19.093 16.718  -51.945  1.00 29.28  ? 294  ASP D OD2 1 
ATOM   12975 N N   . ILE D 1 302 ? -18.449 14.791  -56.689  1.00 23.46  ? 295  ILE D N   1 
ATOM   12976 C CA  . ILE D 1 302 ? -17.750 14.027  -57.751  1.00 22.02  ? 295  ILE D CA  1 
ATOM   12977 C C   . ILE D 1 302 ? -18.673 12.892  -58.191  1.00 21.55  ? 295  ILE D C   1 
ATOM   12978 O O   . ILE D 1 302 ? -19.172 12.157  -57.314  1.00 21.22  ? 295  ILE D O   1 
ATOM   12979 C CB  . ILE D 1 302 ? -16.395 13.479  -57.265  1.00 20.62  ? 295  ILE D CB  1 
ATOM   12980 C CG1 . ILE D 1 302 ? -15.511 14.561  -56.640  1.00 19.89  ? 295  ILE D CG1 1 
ATOM   12981 C CG2 . ILE D 1 302 ? -15.698 12.757  -58.406  1.00 20.81  ? 295  ILE D CG2 1 
ATOM   12982 C CD1 . ILE D 1 302 ? -14.293 14.016  -55.926  1.00 18.80  ? 295  ILE D CD1 1 
ATOM   12983 N N   . LEU D 1 303 ? -18.840 12.752  -59.504  1.00 21.41  ? 296  LEU D N   1 
ATOM   12984 C CA  . LEU D 1 303 ? -19.674 11.726  -60.162  1.00 22.68  ? 296  LEU D CA  1 
ATOM   12985 C C   . LEU D 1 303 ? -18.795 10.878  -61.091  1.00 24.10  ? 296  LEU D C   1 
ATOM   12986 O O   . LEU D 1 303 ? -18.000 11.447  -61.891  1.00 23.92  ? 296  LEU D O   1 
ATOM   12987 C CB  . LEU D 1 303 ? -20.769 12.448  -60.944  1.00 23.17  ? 296  LEU D CB  1 
ATOM   12988 C CG  . LEU D 1 303 ? -21.695 11.542  -61.750  1.00 23.37  ? 296  LEU D CG  1 
ATOM   12989 C CD1 . LEU D 1 303 ? -22.457 10.581  -60.846  1.00 22.81  ? 296  LEU D CD1 1 
ATOM   12990 C CD2 . LEU D 1 303 ? -22.650 12.378  -62.587  1.00 23.86  ? 296  LEU D CD2 1 
ATOM   12991 N N   . CYS D 1 304 ? -18.938 9.558   -60.989  1.00 23.77  ? 297  CYS D N   1 
ATOM   12992 C CA  . CYS D 1 304 ? -18.190 8.571   -61.799  1.00 22.54  ? 297  CYS D CA  1 
ATOM   12993 C C   . CYS D 1 304 ? -19.134 7.906   -62.800  1.00 23.44  ? 297  CYS D C   1 
ATOM   12994 O O   . CYS D 1 304 ? -20.234 7.433   -62.394  1.00 19.34  ? 297  CYS D O   1 
ATOM   12995 C CB  . CYS D 1 304 ? -17.535 7.529   -60.911  1.00 22.99  ? 297  CYS D CB  1 
ATOM   12996 S SG  . CYS D 1 304 ? -16.379 8.276   -59.735  1.00 20.63  ? 297  CYS D SG  1 
ATOM   12997 N N   . LEU D 1 305 ? -18.684 7.871   -64.061  1.00 21.23  ? 298  LEU D N   1 
ATOM   12998 C CA  . LEU D 1 305 ? -19.417 7.269   -65.186  1.00 21.68  ? 298  LEU D CA  1 
ATOM   12999 C C   . LEU D 1 305 ? -18.476 6.380   -65.986  1.00 21.07  ? 298  LEU D C   1 
ATOM   13000 O O   . LEU D 1 305 ? -17.306 6.740   -66.143  1.00 22.26  ? 298  LEU D O   1 
ATOM   13001 C CB  . LEU D 1 305 ? -19.946 8.389   -66.076  1.00 22.50  ? 298  LEU D CB  1 
ATOM   13002 C CG  . LEU D 1 305 ? -20.942 9.345   -65.422  1.00 22.59  ? 298  LEU D CG  1 
ATOM   13003 C CD1 . LEU D 1 305 ? -21.391 10.400  -66.420  1.00 23.45  ? 298  LEU D CD1 1 
ATOM   13004 C CD2 . LEU D 1 305 ? -22.152 8.591   -64.886  1.00 22.33  ? 298  LEU D CD2 1 
ATOM   13005 N N   . ALA D 1 306 ? -19.017 5.285   -66.503  1.00 20.73  ? 299  ALA D N   1 
ATOM   13006 C CA  . ALA D 1 306 ? -18.404 4.418   -67.527  1.00 21.14  ? 299  ALA D CA  1 
ATOM   13007 C C   . ALA D 1 306 ? -19.509 3.547   -68.135  1.00 20.49  ? 299  ALA D C   1 
ATOM   13008 O O   . ALA D 1 306 ? -20.625 4.052   -68.257  1.00 21.46  ? 299  ALA D O   1 
ATOM   13009 C CB  . ALA D 1 306 ? -17.274 3.630   -66.912  1.00 21.43  ? 299  ALA D CB  1 
ATOM   13010 N N   . LYS D 1 307 ? -19.206 2.289   -68.457  1.00 20.57  ? 300  LYS D N   1 
ATOM   13011 C CA  . LYS D 1 307 ? -20.092 1.299   -69.124  1.00 20.59  ? 300  LYS D CA  1 
ATOM   13012 C C   . LYS D 1 307 ? -20.882 1.969   -70.263  1.00 20.57  ? 300  LYS D C   1 
ATOM   13013 O O   . LYS D 1 307 ? -20.294 2.217   -71.323  1.00 18.55  ? 300  LYS D O   1 
ATOM   13014 C CB  . LYS D 1 307 ? -20.942 0.614   -68.059  1.00 20.86  ? 300  LYS D CB  1 
ATOM   13015 C CG  . LYS D 1 307 ? -20.123 -0.066  -66.981  1.00 22.63  ? 300  LYS D CG  1 
ATOM   13016 C CD  . LYS D 1 307 ? -20.857 -1.096  -66.150  1.00 23.37  ? 300  LYS D CD  1 
ATOM   13017 C CE  . LYS D 1 307 ? -19.935 -2.252  -65.858  1.00 23.90  ? 300  LYS D CE  1 
ATOM   13018 N NZ  . LYS D 1 307 ? -20.454 -3.163  -64.822  1.00 27.15  ? 300  LYS D NZ  1 
ATOM   13019 N N   . ALA D 1 308 ? -22.156 2.295   -70.034  1.00 20.19  ? 301  ALA D N   1 
ATOM   13020 C CA  . ALA D 1 308 ? -23.100 2.720   -71.083  1.00 20.60  ? 301  ALA D CA  1 
ATOM   13021 C C   . ALA D 1 308 ? -22.660 4.050   -71.702  1.00 19.26  ? 301  ALA D C   1 
ATOM   13022 O O   . ALA D 1 308 ? -23.099 4.321   -72.816  1.00 17.72  ? 301  ALA D O   1 
ATOM   13023 C CB  . ALA D 1 308 ? -24.502 2.801   -70.521  1.00 20.72  ? 301  ALA D CB  1 
ATOM   13024 N N   . LEU D 1 309 ? -21.837 4.857   -71.033  1.00 18.04  ? 302  LEU D N   1 
ATOM   13025 C CA  . LEU D 1 309 ? -21.428 6.171   -71.594  1.00 18.66  ? 302  LEU D CA  1 
ATOM   13026 C C   . LEU D 1 309 ? -20.773 5.991   -72.977  1.00 20.01  ? 302  LEU D C   1 
ATOM   13027 O O   . LEU D 1 309 ? -20.792 6.952   -73.757  1.00 20.74  ? 302  LEU D O   1 
ATOM   13028 C CB  . LEU D 1 309 ? -20.473 6.849   -70.612  1.00 18.76  ? 302  LEU D CB  1 
ATOM   13029 C CG  . LEU D 1 309 ? -19.991 8.237   -71.022  1.00 18.55  ? 302  LEU D CG  1 
ATOM   13030 C CD1 . LEU D 1 309 ? -21.159 9.179   -71.127  1.00 18.52  ? 302  LEU D CD1 1 
ATOM   13031 C CD2 . LEU D 1 309 ? -18.953 8.762   -70.058  1.00 19.38  ? 302  LEU D CD2 1 
ATOM   13032 N N   . GLY D 1 310 ? -20.191 4.822   -73.276  1.00 19.90  ? 303  GLY D N   1 
ATOM   13033 C CA  . GLY D 1 310 ? -19.505 4.548   -74.556  1.00 20.01  ? 303  GLY D CA  1 
ATOM   13034 C C   . GLY D 1 310 ? -20.436 3.993   -75.620  1.00 20.06  ? 303  GLY D C   1 
ATOM   13035 O O   . GLY D 1 310 ? -19.985 3.763   -76.759  1.00 19.12  ? 303  GLY D O   1 
ATOM   13036 N N   . GLY D 1 311 ? -21.698 3.759   -75.272  1.00 20.34  ? 304  GLY D N   1 
ATOM   13037 C CA  . GLY D 1 311 ? -22.742 3.404   -76.253  1.00 20.97  ? 304  GLY D CA  1 
ATOM   13038 C C   . GLY D 1 311 ? -22.688 1.940   -76.659  1.00 20.97  ? 304  GLY D C   1 
ATOM   13039 O O   . GLY D 1 311 ? -23.360 1.603   -77.645  1.00 22.01  ? 304  GLY D O   1 
ATOM   13040 N N   . GLY D 1 312 ? -21.940 1.097   -75.929  1.00 20.01  ? 305  GLY D N   1 
ATOM   13041 C CA  . GLY D 1 312 ? -21.712 -0.317  -76.282  1.00 19.01  ? 305  GLY D CA  1 
ATOM   13042 C C   . GLY D 1 312 ? -20.871 -0.440  -77.544  1.00 17.48  ? 305  GLY D C   1 
ATOM   13043 O O   . GLY D 1 312 ? -20.920 -1.481  -78.244  1.00 15.27  ? 305  GLY D O   1 
ATOM   13044 N N   . VAL D 1 313 ? -20.113 0.602   -77.835  1.00 18.43  ? 306  VAL D N   1 
ATOM   13045 C CA  . VAL D 1 313 ? -19.157 0.611   -78.984  1.00 21.02  ? 306  VAL D CA  1 
ATOM   13046 C C   . VAL D 1 313 ? -17.737 0.863   -78.467  1.00 19.86  ? 306  VAL D C   1 
ATOM   13047 O O   . VAL D 1 313 ? -16.874 0.037   -78.779  1.00 22.18  ? 306  VAL D O   1 
ATOM   13048 C CB  . VAL D 1 313 ? -19.598 1.621   -80.056  1.00 21.07  ? 306  VAL D CB  1 
ATOM   13049 C CG1 . VAL D 1 313 ? -18.690 1.584   -81.262  1.00 21.56  ? 306  VAL D CG1 1 
ATOM   13050 C CG2 . VAL D 1 313 ? -21.043 1.375   -80.464  1.00 21.11  ? 306  VAL D CG2 1 
ATOM   13051 N N   . MET D 1 314 ? -17.533 1.913   -77.661  1.00 21.19  ? 307  MET D N   1 
ATOM   13052 C CA  . MET D 1 314 ? -16.195 2.328   -77.141  1.00 22.80  ? 307  MET D CA  1 
ATOM   13053 C C   . MET D 1 314 ? -16.083 2.150   -75.625  1.00 23.76  ? 307  MET D C   1 
ATOM   13054 O O   . MET D 1 314 ? -17.049 2.380   -74.879  1.00 22.21  ? 307  MET D O   1 
ATOM   13055 C CB  . MET D 1 314 ? -15.916 3.797   -77.481  1.00 23.84  ? 307  MET D CB  1 
ATOM   13056 C CG  . MET D 1 314 ? -15.542 4.016   -78.941  1.00 23.83  ? 307  MET D CG  1 
ATOM   13057 S SD  . MET D 1 314 ? -14.083 3.055   -79.419  1.00 25.63  ? 307  MET D SD  1 
ATOM   13058 C CE  . MET D 1 314 ? -12.784 3.998   -78.623  1.00 23.38  ? 307  MET D CE  1 
ATOM   13059 N N   . PRO D 1 315 ? -14.883 1.757   -75.128  1.00 23.27  ? 308  PRO D N   1 
ATOM   13060 C CA  . PRO D 1 315 ? -14.548 1.873   -73.716  1.00 22.86  ? 308  PRO D CA  1 
ATOM   13061 C C   . PRO D 1 315 ? -14.303 3.350   -73.409  1.00 22.70  ? 308  PRO D C   1 
ATOM   13062 O O   . PRO D 1 315 ? -13.543 3.976   -74.132  1.00 23.35  ? 308  PRO D O   1 
ATOM   13063 C CB  . PRO D 1 315 ? -13.255 1.073   -73.571  1.00 23.74  ? 308  PRO D CB  1 
ATOM   13064 C CG  . PRO D 1 315 ? -12.607 1.218   -74.913  1.00 23.32  ? 308  PRO D CG  1 
ATOM   13065 C CD  . PRO D 1 315 ? -13.770 1.184   -75.891  1.00 23.97  ? 308  PRO D CD  1 
ATOM   13066 N N   . ILE D 1 316 ? -14.989 3.866   -72.392  1.00 22.87  ? 309  ILE D N   1 
ATOM   13067 C CA  . ILE D 1 316 ? -14.768 5.240   -71.855  1.00 23.65  ? 309  ILE D CA  1 
ATOM   13068 C C   . ILE D 1 316 ? -15.156 5.265   -70.374  1.00 21.52  ? 309  ILE D C   1 
ATOM   13069 O O   . ILE D 1 316 ? -16.024 4.491   -69.982  1.00 21.35  ? 309  ILE D O   1 
ATOM   13070 C CB  . ILE D 1 316 ? -15.552 6.285   -72.673  1.00 25.57  ? 309  ILE D CB  1 
ATOM   13071 C CG1 . ILE D 1 316 ? -15.259 7.721   -72.221  1.00 26.69  ? 309  ILE D CG1 1 
ATOM   13072 C CG2 . ILE D 1 316 ? -17.038 5.991   -72.617  1.00 26.67  ? 309  ILE D CG2 1 
ATOM   13073 C CD1 . ILE D 1 316 ? -15.845 8.773   -73.152  1.00 26.77  ? 309  ILE D CD1 1 
ATOM   13074 N N   . GLY D 1 317 ? -14.489 6.114   -69.599  1.00 19.57  ? 310  GLY D N   1 
ATOM   13075 C CA  . GLY D 1 317 ? -14.921 6.542   -68.260  1.00 19.89  ? 310  GLY D CA  1 
ATOM   13076 C C   . GLY D 1 317 ? -14.909 8.051   -68.176  1.00 19.32  ? 310  GLY D C   1 
ATOM   13077 O O   . GLY D 1 317 ? -14.188 8.679   -68.933  1.00 17.16  ? 310  GLY D O   1 
ATOM   13078 N N   . ALA D 1 318 ? -15.713 8.618   -67.292  1.00 20.87  ? 311  ALA D N   1 
ATOM   13079 C CA  . ALA D 1 318 ? -15.724 10.067  -67.017  1.00 22.81  ? 311  ALA D CA  1 
ATOM   13080 C C   . ALA D 1 318 ? -15.819 10.282  -65.511  1.00 24.75  ? 311  ALA D C   1 
ATOM   13081 O O   . ALA D 1 318 ? -16.611 9.592   -64.848  1.00 28.65  ? 311  ALA D O   1 
ATOM   13082 C CB  . ALA D 1 318 ? -16.862 10.728  -67.731  1.00 23.08  ? 311  ALA D CB  1 
ATOM   13083 N N   . THR D 1 319 ? -15.023 11.212  -65.012  1.00 26.49  ? 312  THR D N   1 
ATOM   13084 C CA  . THR D 1 319 ? -15.096 11.715  -63.632  1.00 26.96  ? 312  THR D CA  1 
ATOM   13085 C C   . THR D 1 319 ? -15.450 13.190  -63.736  1.00 27.25  ? 312  THR D C   1 
ATOM   13086 O O   . THR D 1 319 ? -14.657 13.935  -64.317  1.00 27.57  ? 312  THR D O   1 
ATOM   13087 C CB  . THR D 1 319 ? -13.781 11.449  -62.903  1.00 29.43  ? 312  THR D CB  1 
ATOM   13088 O OG1 . THR D 1 319 ? -13.467 10.064  -63.092  1.00 29.67  ? 312  THR D OG1 1 
ATOM   13089 C CG2 . THR D 1 319 ? -13.862 11.799  -61.430  1.00 29.46  ? 312  THR D CG2 1 
ATOM   13090 N N   . ILE D 1 320 ? -16.624 13.569  -63.243  1.00 27.34  ? 313  ILE D N   1 
ATOM   13091 C CA  . ILE D 1 320 ? -17.101 14.979  -63.283  1.00 27.75  ? 313  ILE D CA  1 
ATOM   13092 C C   . ILE D 1 320 ? -17.158 15.469  -61.840  1.00 25.03  ? 313  ILE D C   1 
ATOM   13093 O O   . ILE D 1 320 ? -17.554 14.682  -60.983  1.00 22.98  ? 313  ILE D O   1 
ATOM   13094 C CB  . ILE D 1 320 ? -18.467 15.087  -63.983  1.00 29.27  ? 313  ILE D CB  1 
ATOM   13095 C CG1 . ILE D 1 320 ? -18.473 14.286  -65.290  1.00 32.38  ? 313  ILE D CG1 1 
ATOM   13096 C CG2 . ILE D 1 320 ? -18.864 16.547  -64.204  1.00 28.69  ? 313  ILE D CG2 1 
ATOM   13097 C CD1 . ILE D 1 320 ? -19.595 13.272  -65.390  1.00 34.14  ? 313  ILE D CD1 1 
ATOM   13098 N N   . ALA D 1 321 ? -16.798 16.728  -61.620  1.00 23.48  ? 314  ALA D N   1 
ATOM   13099 C CA  . ALA D 1 321 ? -16.710 17.342  -60.284  1.00 24.04  ? 314  ALA D CA  1 
ATOM   13100 C C   . ALA D 1 321 ? -17.002 18.833  -60.370  1.00 23.74  ? 314  ALA D C   1 
ATOM   13101 O O   . ALA D 1 321 ? -16.981 19.378  -61.466  1.00 25.61  ? 314  ALA D O   1 
ATOM   13102 C CB  . ALA D 1 321 ? -15.339 17.099  -59.723  1.00 23.46  ? 314  ALA D CB  1 
ATOM   13103 N N   . THR D 1 322 ? -17.257 19.448  -59.227  1.00 24.44  ? 315  THR D N   1 
ATOM   13104 C CA  . THR D 1 322 ? -17.404 20.909  -59.041  1.00 26.05  ? 315  THR D CA  1 
ATOM   13105 C C   . THR D 1 322 ? -16.099 21.601  -59.441  1.00 26.07  ? 315  THR D C   1 
ATOM   13106 O O   . THR D 1 322 ? -15.045 20.953  -59.367  1.00 23.73  ? 315  THR D O   1 
ATOM   13107 C CB  . THR D 1 322 ? -17.741 21.220  -57.574  1.00 27.44  ? 315  THR D CB  1 
ATOM   13108 O OG1 . THR D 1 322 ? -16.744 20.597  -56.765  1.00 27.28  ? 315  THR D OG1 1 
ATOM   13109 C CG2 . THR D 1 322 ? -19.101 20.719  -57.145  1.00 28.91  ? 315  THR D CG2 1 
ATOM   13110 N N   . GLU D 1 323 ? -16.173 22.876  -59.818  1.00 28.14  ? 316  GLU D N   1 
ATOM   13111 C CA  . GLU D 1 323 ? -14.982 23.736  -60.039  1.00 31.75  ? 316  GLU D CA  1 
ATOM   13112 C C   . GLU D 1 323 ? -14.171 23.770  -58.745  1.00 30.05  ? 316  GLU D C   1 
ATOM   13113 O O   . GLU D 1 323 ? -12.933 23.736  -58.833  1.00 27.95  ? 316  GLU D O   1 
ATOM   13114 C CB  . GLU D 1 323 ? -15.387 25.140  -60.494  1.00 35.63  ? 316  GLU D CB  1 
ATOM   13115 C CG  . GLU D 1 323 ? -14.207 26.083  -60.689  1.00 39.11  ? 316  GLU D CG  1 
ATOM   13116 C CD  . GLU D 1 323 ? -14.380 27.147  -61.758  1.00 45.28  ? 316  GLU D CD  1 
ATOM   13117 O OE1 . GLU D 1 323 ? -15.465 27.173  -62.399  1.00 47.99  ? 316  GLU D OE1 1 
ATOM   13118 O OE2 . GLU D 1 323 ? -13.415 27.929  -61.972  1.00 53.36  ? 316  GLU D OE2 1 
ATOM   13119 N N   . GLU D 1 324 ? -14.864 23.820  -57.598  1.00 32.17  ? 317  GLU D N   1 
ATOM   13120 C CA  . GLU D 1 324 ? -14.268 23.912  -56.237  1.00 35.00  ? 317  GLU D CA  1 
ATOM   13121 C C   . GLU D 1 324 ? -13.257 22.766  -56.057  1.00 33.75  ? 317  GLU D C   1 
ATOM   13122 O O   . GLU D 1 324 ? -12.118 23.058  -55.661  1.00 33.61  ? 317  GLU D O   1 
ATOM   13123 C CB  . GLU D 1 324 ? -15.385 23.928  -55.179  1.00 39.91  ? 317  GLU D CB  1 
ATOM   13124 C CG  . GLU D 1 324 ? -14.914 24.042  -53.729  1.00 43.44  ? 317  GLU D CG  1 
ATOM   13125 C CD  . GLU D 1 324 ? -13.993 25.214  -53.411  1.00 48.26  ? 317  GLU D CD  1 
ATOM   13126 O OE1 . GLU D 1 324 ? -14.064 26.261  -54.111  1.00 57.39  ? 317  GLU D OE1 1 
ATOM   13127 O OE2 . GLU D 1 324 ? -13.194 25.081  -52.469  1.00 49.05  ? 317  GLU D OE2 1 
ATOM   13128 N N   . VAL D 1 325 ? -13.649 21.531  -56.390  1.00 31.41  ? 318  VAL D N   1 
ATOM   13129 C CA  . VAL D 1 325 ? -12.839 20.287  -56.212  1.00 29.34  ? 318  VAL D CA  1 
ATOM   13130 C C   . VAL D 1 325 ? -11.843 20.130  -57.364  1.00 28.07  ? 318  VAL D C   1 
ATOM   13131 O O   . VAL D 1 325 ? -10.661 19.845  -57.103  1.00 29.10  ? 318  VAL D O   1 
ATOM   13132 C CB  . VAL D 1 325 ? -13.753 19.054  -56.111  1.00 28.84  ? 318  VAL D CB  1 
ATOM   13133 C CG1 . VAL D 1 325 ? -12.969 17.760  -56.191  1.00 28.69  ? 318  VAL D CG1 1 
ATOM   13134 C CG2 . VAL D 1 325 ? -14.588 19.093  -54.846  1.00 29.17  ? 318  VAL D CG2 1 
ATOM   13135 N N   . PHE D 1 326 ? -12.309 20.247  -58.602  1.00 27.95  ? 319  PHE D N   1 
ATOM   13136 C CA  . PHE D 1 326 ? -11.503 19.936  -59.807  1.00 27.90  ? 319  PHE D CA  1 
ATOM   13137 C C   . PHE D 1 326 ? -10.345 20.935  -59.915  1.00 28.53  ? 319  PHE D C   1 
ATOM   13138 O O   . PHE D 1 326 ? -9.291  20.545  -60.421  1.00 28.95  ? 319  PHE D O   1 
ATOM   13139 C CB  . PHE D 1 326 ? -12.398 19.938  -61.044  1.00 28.46  ? 319  PHE D CB  1 
ATOM   13140 C CG  . PHE D 1 326 ? -11.949 19.037  -62.165  1.00 30.50  ? 319  PHE D CG  1 
ATOM   13141 C CD1 . PHE D 1 326 ? -10.977 19.457  -63.059  1.00 31.02  ? 319  PHE D CD1 1 
ATOM   13142 C CD2 . PHE D 1 326 ? -12.532 17.787  -62.357  1.00 31.42  ? 319  PHE D CD2 1 
ATOM   13143 C CE1 . PHE D 1 326 ? -10.576 18.627  -64.097  1.00 32.96  ? 319  PHE D CE1 1 
ATOM   13144 C CE2 . PHE D 1 326 ? -12.132 16.964  -63.402  1.00 30.66  ? 319  PHE D CE2 1 
ATOM   13145 C CZ  . PHE D 1 326 ? -11.151 17.382  -64.268  1.00 32.08  ? 319  PHE D CZ  1 
ATOM   13146 N N   . SER D 1 327 ? -10.516 22.163  -59.408  1.00 30.33  ? 320  SER D N   1 
ATOM   13147 C CA  . SER D 1 327 ? -9.527  23.274  -59.518  1.00 31.58  ? 320  SER D CA  1 
ATOM   13148 C C   . SER D 1 327 ? -8.172  22.861  -58.932  1.00 33.67  ? 320  SER D C   1 
ATOM   13149 O O   . SER D 1 327 ? -7.177  23.608  -59.141  1.00 34.99  ? 320  SER D O   1 
ATOM   13150 C CB  . SER D 1 327 ? -10.025 24.550  -58.889  1.00 32.09  ? 320  SER D CB  1 
ATOM   13151 O OG  . SER D 1 327 ? -10.243 24.378  -57.509  1.00 32.86  ? 320  SER D OG  1 
ATOM   13152 N N   . VAL D 1 328 ? -8.115  21.715  -58.244  1.00 33.85  ? 321  VAL D N   1 
ATOM   13153 C CA  . VAL D 1 328 ? -6.836  21.134  -57.730  1.00 33.06  ? 321  VAL D CA  1 
ATOM   13154 C C   . VAL D 1 328 ? -5.914  20.779  -58.904  1.00 31.62  ? 321  VAL D C   1 
ATOM   13155 O O   . VAL D 1 328 ? -4.690  20.668  -58.644  1.00 32.25  ? 321  VAL D O   1 
ATOM   13156 C CB  . VAL D 1 328 ? -7.052  19.917  -56.805  1.00 33.61  ? 321  VAL D CB  1 
ATOM   13157 C CG1 . VAL D 1 328 ? -7.807  20.303  -55.536  1.00 33.17  ? 321  VAL D CG1 1 
ATOM   13158 C CG2 . VAL D 1 328 ? -7.727  18.747  -57.507  1.00 33.71  ? 321  VAL D CG2 1 
ATOM   13159 N N   . LEU D 1 329 ? -6.460  20.613  -60.122  1.00 28.65  ? 322  LEU D N   1 
ATOM   13160 C CA  . LEU D 1 329 ? -5.699  20.171  -61.327  1.00 29.69  ? 322  LEU D CA  1 
ATOM   13161 C C   . LEU D 1 329 ? -5.301  21.355  -62.223  1.00 30.57  ? 322  LEU D C   1 
ATOM   13162 O O   . LEU D 1 329 ? -4.620  21.107  -63.225  1.00 28.77  ? 322  LEU D O   1 
ATOM   13163 C CB  . LEU D 1 329 ? -6.537  19.167  -62.121  1.00 27.52  ? 322  LEU D CB  1 
ATOM   13164 C CG  . LEU D 1 329 ? -6.963  17.897  -61.382  1.00 26.98  ? 322  LEU D CG  1 
ATOM   13165 C CD1 . LEU D 1 329 ? -7.601  16.909  -62.341  1.00 27.68  ? 322  LEU D CD1 1 
ATOM   13166 C CD2 . LEU D 1 329 ? -5.810  17.224  -60.676  1.00 27.20  ? 322  LEU D CD2 1 
ATOM   13167 N N   . PHE D 1 330 ? -5.648  22.588  -61.849  1.00 34.56  ? 323  PHE D N   1 
ATOM   13168 C CA  . PHE D 1 330 ? -5.511  23.798  -62.704  1.00 37.49  ? 323  PHE D CA  1 
ATOM   13169 C C   . PHE D 1 330 ? -4.066  24.314  -62.748  1.00 42.01  ? 323  PHE D C   1 
ATOM   13170 O O   . PHE D 1 330 ? -3.654  24.784  -63.825  1.00 46.46  ? 323  PHE D O   1 
ATOM   13171 C CB  . PHE D 1 330 ? -6.452  24.908  -62.227  1.00 37.07  ? 323  PHE D CB  1 
ATOM   13172 C CG  . PHE D 1 330 ? -7.919  24.663  -62.482  1.00 35.76  ? 323  PHE D CG  1 
ATOM   13173 C CD1 . PHE D 1 330 ? -8.368  23.474  -63.046  1.00 36.64  ? 323  PHE D CD1 1 
ATOM   13174 C CD2 . PHE D 1 330 ? -8.861  25.618  -62.125  1.00 35.73  ? 323  PHE D CD2 1 
ATOM   13175 C CE1 . PHE D 1 330 ? -9.718  23.254  -63.266  1.00 37.15  ? 323  PHE D CE1 1 
ATOM   13176 C CE2 . PHE D 1 330 ? -10.212 25.403  -62.355  1.00 35.79  ? 323  PHE D CE2 1 
ATOM   13177 C CZ  . PHE D 1 330 ? -10.635 24.220  -62.924  1.00 36.21  ? 323  PHE D CZ  1 
ATOM   13178 N N   . ASP D 1 331 ? -3.344  24.307  -61.623  1.00 45.62  ? 324  ASP D N   1 
ATOM   13179 C CA  . ASP D 1 331 ? -1.975  24.889  -61.534  1.00 53.14  ? 324  ASP D CA  1 
ATOM   13180 C C   . ASP D 1 331 ? -0.976  23.943  -62.193  1.00 49.84  ? 324  ASP D C   1 
ATOM   13181 O O   . ASP D 1 331 ? -0.022  24.456  -62.788  1.00 50.39  ? 324  ASP D O   1 
ATOM   13182 C CB  . ASP D 1 331 ? -1.533  25.186  -60.100  1.00 60.67  ? 324  ASP D CB  1 
ATOM   13183 C CG  . ASP D 1 331 ? -2.144  26.464  -59.542  1.00 73.01  ? 324  ASP D CG  1 
ATOM   13184 O OD1 . ASP D 1 331 ? -2.928  27.113  -60.266  1.00 81.42  ? 324  ASP D OD1 1 
ATOM   13185 O OD2 . ASP D 1 331 ? -1.846  26.800  -58.379  1.00 89.42  ? 324  ASP D OD2 1 
ATOM   13186 N N   . ASN D 1 332 ? -1.166  22.631  -62.031  1.00 45.04  ? 325  ASN D N   1 
ATOM   13187 C CA  . ASN D 1 332 ? -0.384  21.578  -62.731  1.00 39.09  ? 325  ASN D CA  1 
ATOM   13188 C C   . ASN D 1 332 ? -1.356  20.626  -63.417  1.00 35.72  ? 325  ASN D C   1 
ATOM   13189 O O   . ASN D 1 332 ? -1.817  19.652  -62.834  1.00 31.85  ? 325  ASN D O   1 
ATOM   13190 C CB  . ASN D 1 332 ? 0.574   20.812  -61.824  1.00 35.93  ? 325  ASN D CB  1 
ATOM   13191 C CG  . ASN D 1 332 ? 1.446   19.851  -62.609  1.00 37.13  ? 325  ASN D CG  1 
ATOM   13192 O OD1 . ASN D 1 332 ? 1.449   19.865  -63.844  1.00 37.29  ? 325  ASN D OD1 1 
ATOM   13193 N ND2 . ASN D 1 332 ? 2.193   19.008  -61.918  1.00 36.51  ? 325  ASN D ND2 1 
ATOM   13194 N N   . PRO D 1 333 ? -1.667  20.875  -64.701  1.00 33.94  ? 326  PRO D N   1 
ATOM   13195 C CA  . PRO D 1 333 ? -2.607  20.032  -65.434  1.00 33.38  ? 326  PRO D CA  1 
ATOM   13196 C C   . PRO D 1 333 ? -2.073  18.628  -65.768  1.00 32.47  ? 326  PRO D C   1 
ATOM   13197 O O   . PRO D 1 333 ? -2.812  17.849  -66.323  1.00 32.02  ? 326  PRO D O   1 
ATOM   13198 C CB  . PRO D 1 333 ? -2.867  20.867  -66.692  1.00 33.85  ? 326  PRO D CB  1 
ATOM   13199 C CG  . PRO D 1 333 ? -1.580  21.638  -66.898  1.00 35.63  ? 326  PRO D CG  1 
ATOM   13200 C CD  . PRO D 1 333 ? -1.131  21.985  -65.501  1.00 34.60  ? 326  PRO D CD  1 
ATOM   13201 N N   . PHE D 1 334 ? -0.836  18.309  -65.396  1.00 32.59  ? 327  PHE D N   1 
ATOM   13202 C CA  . PHE D 1 334 ? -0.256  16.956  -65.596  1.00 35.69  ? 327  PHE D CA  1 
ATOM   13203 C C   . PHE D 1 334 ? -0.341  16.160  -64.300  1.00 34.02  ? 327  PHE D C   1 
ATOM   13204 O O   . PHE D 1 334 ? 0.142   15.030  -64.265  1.00 34.04  ? 327  PHE D O   1 
ATOM   13205 C CB  . PHE D 1 334 ? 1.174   17.058  -66.127  1.00 42.16  ? 327  PHE D CB  1 
ATOM   13206 C CG  . PHE D 1 334 ? 1.206   17.814  -67.426  1.00 46.34  ? 327  PHE D CG  1 
ATOM   13207 C CD1 . PHE D 1 334 ? 0.655   17.252  -68.566  1.00 48.53  ? 327  PHE D CD1 1 
ATOM   13208 C CD2 . PHE D 1 334 ? 1.671   19.120  -67.481  1.00 48.61  ? 327  PHE D CD2 1 
ATOM   13209 C CE1 . PHE D 1 334 ? 0.636   17.954  -69.760  1.00 51.43  ? 327  PHE D CE1 1 
ATOM   13210 C CE2 . PHE D 1 334 ? 1.634   19.828  -68.671  1.00 51.35  ? 327  PHE D CE2 1 
ATOM   13211 C CZ  . PHE D 1 334 ? 1.122   19.241  -69.808  1.00 53.09  ? 327  PHE D CZ  1 
ATOM   13212 N N   . LEU D 1 335 ? -0.964  16.723  -63.277  1.00 31.94  ? 328  LEU D N   1 
ATOM   13213 C CA  . LEU D 1 335 ? -1.022  16.070  -61.954  1.00 30.90  ? 328  LEU D CA  1 
ATOM   13214 C C   . LEU D 1 335 ? -1.741  14.725  -62.080  1.00 29.60  ? 328  LEU D C   1 
ATOM   13215 O O   . LEU D 1 335 ? -1.315  13.749  -61.444  1.00 28.43  ? 328  LEU D O   1 
ATOM   13216 C CB  . LEU D 1 335 ? -1.742  17.027  -61.010  1.00 31.44  ? 328  LEU D CB  1 
ATOM   13217 C CG  . LEU D 1 335 ? -1.398  16.875  -59.541  1.00 30.66  ? 328  LEU D CG  1 
ATOM   13218 C CD1 . LEU D 1 335 ? 0.104   16.712  -59.350  1.00 29.44  ? 328  LEU D CD1 1 
ATOM   13219 C CD2 . LEU D 1 335 ? -1.948  18.069  -58.754  1.00 32.14  ? 328  LEU D CD2 1 
ATOM   13220 N N   . HIS D 1 336 ? -2.811  14.687  -62.868  1.00 29.76  ? 329  HIS D N   1 
ATOM   13221 C CA  . HIS D 1 336 ? -3.520  13.448  -63.285  1.00 29.94  ? 329  HIS D CA  1 
ATOM   13222 C C   . HIS D 1 336 ? -3.708  13.491  -64.803  1.00 30.22  ? 329  HIS D C   1 
ATOM   13223 O O   . HIS D 1 336 ? -4.269  14.500  -65.314  1.00 30.27  ? 329  HIS D O   1 
ATOM   13224 C CB  . HIS D 1 336 ? -4.859  13.272  -62.546  1.00 28.84  ? 329  HIS D CB  1 
ATOM   13225 C CG  . HIS D 1 336 ? -5.439  11.902  -62.723  1.00 28.82  ? 329  HIS D CG  1 
ATOM   13226 N ND1 . HIS D 1 336 ? -4.736  10.750  -62.379  1.00 27.96  ? 329  HIS D ND1 1 
ATOM   13227 C CD2 . HIS D 1 336 ? -6.628  11.485  -63.219  1.00 26.64  ? 329  HIS D CD2 1 
ATOM   13228 C CE1 . HIS D 1 336 ? -5.471  9.689   -62.645  1.00 28.23  ? 329  HIS D CE1 1 
ATOM   13229 N NE2 . HIS D 1 336 ? -6.648  10.113  -63.155  1.00 26.54  ? 329  HIS D NE2 1 
ATOM   13230 N N   . THR D 1 337 ? -3.262  12.435  -65.481  1.00 31.10  ? 330  THR D N   1 
ATOM   13231 C CA  . THR D 1 337 ? -3.355  12.264  -66.951  1.00 31.39  ? 330  THR D CA  1 
ATOM   13232 C C   . THR D 1 337 ? -3.544  10.786  -67.282  1.00 32.90  ? 330  THR D C   1 
ATOM   13233 O O   . THR D 1 337 ? -3.371  9.939   -66.382  1.00 30.58  ? 330  THR D O   1 
ATOM   13234 C CB  . THR D 1 337 ? -2.103  12.815  -67.641  1.00 34.21  ? 330  THR D CB  1 
ATOM   13235 O OG1 . THR D 1 337 ? -0.929  12.106  -67.226  1.00 30.36  ? 330  THR D OG1 1 
ATOM   13236 C CG2 . THR D 1 337 ? -1.929  14.287  -67.360  1.00 35.39  ? 330  THR D CG2 1 
ATOM   13237 N N   . THR D 1 338 ? -3.927  10.507  -68.528  1.00 36.83  ? 331  THR D N   1 
ATOM   13238 C CA  . THR D 1 338 ? -3.957  9.147   -69.122  1.00 37.74  ? 331  THR D CA  1 
ATOM   13239 C C   . THR D 1 338 ? -3.641  9.363   -70.598  1.00 36.03  ? 331  THR D C   1 
ATOM   13240 O O   . THR D 1 338 ? -3.824  10.494  -71.096  1.00 33.38  ? 331  THR D O   1 
ATOM   13241 C CB  . THR D 1 338 ? -5.268  8.412   -68.782  1.00 38.56  ? 331  THR D CB  1 
ATOM   13242 O OG1 . THR D 1 338 ? -5.145  6.997   -68.950  1.00 44.60  ? 331  THR D OG1 1 
ATOM   13243 C CG2 . THR D 1 338 ? -6.419  8.897   -69.614  1.00 33.73  ? 331  THR D CG2 1 
ATOM   13244 N N   A THR D 1 339 ? -3.124  8.337   -71.272  0.50 36.77  ? 332  THR D N   1 
ATOM   13245 N N   B THR D 1 339 ? -3.195  8.298   -71.263  0.50 34.57  ? 332  THR D N   1 
ATOM   13246 C CA  A THR D 1 339 ? -2.686  8.403   -72.687  0.50 38.65  ? 332  THR D CA  1 
ATOM   13247 C CA  B THR D 1 339 ? -2.671  8.334   -72.652  0.50 35.09  ? 332  THR D CA  1 
ATOM   13248 C C   A THR D 1 339 ? -3.926  8.383   -73.591  0.50 34.41  ? 332  THR D C   1 
ATOM   13249 C C   B THR D 1 339 ? -3.865  8.307   -73.623  0.50 32.64  ? 332  THR D C   1 
ATOM   13250 O O   A THR D 1 339 ? -4.060  9.280   -74.440  0.50 32.73  ? 332  THR D O   1 
ATOM   13251 O O   B THR D 1 339 ? -3.907  9.134   -74.543  0.50 31.41  ? 332  THR D O   1 
ATOM   13252 C CB  A THR D 1 339 ? -1.650  7.301   -72.940  0.50 41.88  ? 332  THR D CB  1 
ATOM   13253 C CB  B THR D 1 339 ? -1.625  7.222   -72.835  0.50 35.45  ? 332  THR D CB  1 
ATOM   13254 O OG1 A THR D 1 339 ? -2.191  6.068   -72.460  0.50 46.12  ? 332  THR D OG1 1 
ATOM   13255 O OG1 B THR D 1 339 ? -0.444  7.604   -72.119  0.50 35.70  ? 332  THR D OG1 1 
ATOM   13256 C CG2 A THR D 1 339 ? -0.355  7.603   -72.227  0.50 41.83  ? 332  THR D CG2 1 
ATOM   13257 C CG2 B THR D 1 339 ? -1.298  6.943   -74.287  0.50 33.78  ? 332  THR D CG2 1 
ATOM   13258 N N   . PHE D 1 340 ? -4.824  7.417   -73.381  1.00 31.63  ? 333  PHE D N   1 
ATOM   13259 C CA  . PHE D 1 340 ? -5.983  7.169   -74.272  1.00 29.27  ? 333  PHE D CA  1 
ATOM   13260 C C   . PHE D 1 340 ? -7.231  7.970   -73.869  1.00 26.77  ? 333  PHE D C   1 
ATOM   13261 O O   . PHE D 1 340 ? -8.168  8.019   -74.658  1.00 29.44  ? 333  PHE D O   1 
ATOM   13262 C CB  . PHE D 1 340 ? -6.304  5.680   -74.243  1.00 28.06  ? 333  PHE D CB  1 
ATOM   13263 C CG  . PHE D 1 340 ? -5.219  4.753   -74.735  1.00 26.98  ? 333  PHE D CG  1 
ATOM   13264 C CD1 . PHE D 1 340 ? -4.639  4.940   -75.985  1.00 25.27  ? 333  PHE D CD1 1 
ATOM   13265 C CD2 . PHE D 1 340 ? -4.854  3.646   -73.988  1.00 24.56  ? 333  PHE D CD2 1 
ATOM   13266 C CE1 . PHE D 1 340 ? -3.707  4.043   -76.475  1.00 24.32  ? 333  PHE D CE1 1 
ATOM   13267 C CE2 . PHE D 1 340 ? -3.913  2.756   -74.473  1.00 25.12  ? 333  PHE D CE2 1 
ATOM   13268 C CZ  . PHE D 1 340 ? -3.342  2.955   -75.717  1.00 25.52  ? 333  PHE D CZ  1 
ATOM   13269 N N   . GLY D 1 341 ? -7.269  8.557   -72.677  1.00 24.83  ? 334  GLY D N   1 
ATOM   13270 C CA  . GLY D 1 341 ? -8.505  9.105   -72.080  1.00 24.47  ? 334  GLY D CA  1 
ATOM   13271 C C   . GLY D 1 341 ? -9.001  10.315  -72.838  1.00 24.01  ? 334  GLY D C   1 
ATOM   13272 O O   . GLY D 1 341 ? -8.181  11.186  -73.141  1.00 23.57  ? 334  GLY D O   1 
ATOM   13273 N N   . GLY D 1 342 ? -10.296 10.364  -73.144  1.00 22.35  ? 335  GLY D N   1 
ATOM   13274 C CA  . GLY D 1 342 ? -10.896 11.476  -73.894  1.00 22.46  ? 335  GLY D CA  1 
ATOM   13275 C C   . GLY D 1 342 ? -10.492 11.433  -75.359  1.00 23.90  ? 335  GLY D C   1 
ATOM   13276 O O   . GLY D 1 342 ? -10.580 12.488  -76.022  1.00 28.18  ? 335  GLY D O   1 
ATOM   13277 N N   . ASN D 1 343 ? -10.108 10.259  -75.875  1.00 20.86  ? 336  ASN D N   1 
ATOM   13278 C CA  . ASN D 1 343 ? -9.803  10.083  -77.315  1.00 19.23  ? 336  ASN D CA  1 
ATOM   13279 C C   . ASN D 1 343 ? -11.059 10.377  -78.138  1.00 18.81  ? 336  ASN D C   1 
ATOM   13280 O O   . ASN D 1 343 ? -12.189 10.226  -77.686  1.00 16.66  ? 336  ASN D O   1 
ATOM   13281 C CB  . ASN D 1 343 ? -9.180  8.724   -77.641  1.00 19.05  ? 336  ASN D CB  1 
ATOM   13282 C CG  . ASN D 1 343 ? -10.131 7.556   -77.519  1.00 18.45  ? 336  ASN D CG  1 
ATOM   13283 O OD1 . ASN D 1 343 ? -10.939 7.304   -78.410  1.00 18.81  ? 336  ASN D OD1 1 
ATOM   13284 N ND2 . ASN D 1 343 ? -10.008 6.820   -76.430  1.00 18.60  ? 336  ASN D ND2 1 
ATOM   13285 N N   . PRO D 1 344 ? -10.862 10.878  -79.373  1.00 19.57  ? 337  PRO D N   1 
ATOM   13286 C CA  . PRO D 1 344 ? -11.971 11.209  -80.269  1.00 19.07  ? 337  PRO D CA  1 
ATOM   13287 C C   . PRO D 1 344 ? -12.994 10.103  -80.582  1.00 19.62  ? 337  PRO D C   1 
ATOM   13288 O O   . PRO D 1 344 ? -14.167 10.439  -80.630  1.00 19.47  ? 337  PRO D O   1 
ATOM   13289 C CB  . PRO D 1 344 ? -11.234 11.611  -81.545  1.00 18.93  ? 337  PRO D CB  1 
ATOM   13290 C CG  . PRO D 1 344 ? -9.918  12.168  -81.058  1.00 18.76  ? 337  PRO D CG  1 
ATOM   13291 C CD  . PRO D 1 344 ? -9.543  11.258  -79.914  1.00 18.58  ? 337  PRO D CD  1 
ATOM   13292 N N   . LEU D 1 345 ? -12.583 8.849   -80.810  1.00 19.17  ? 338  LEU D N   1 
ATOM   13293 C CA  . LEU D 1 345 ? -13.551 7.726   -80.986  1.00 20.29  ? 338  LEU D CA  1 
ATOM   13294 C C   . LEU D 1 345 ? -14.459 7.636   -79.755  1.00 20.42  ? 338  LEU D C   1 
ATOM   13295 O O   . LEU D 1 345 ? -15.691 7.593   -79.893  1.00 17.87  ? 338  LEU D O   1 
ATOM   13296 C CB  . LEU D 1 345 ? -12.829 6.387   -81.136  1.00 21.21  ? 338  LEU D CB  1 
ATOM   13297 C CG  . LEU D 1 345 ? -12.163 6.098   -82.472  1.00 23.75  ? 338  LEU D CG  1 
ATOM   13298 C CD1 . LEU D 1 345 ? -11.892 4.606   -82.617  1.00 24.84  ? 338  LEU D CD1 1 
ATOM   13299 C CD2 . LEU D 1 345 ? -12.995 6.615   -83.643  1.00 24.45  ? 338  LEU D CD2 1 
ATOM   13300 N N   . ALA D 1 346 ? -13.847 7.550   -78.579  1.00 20.81  ? 339  ALA D N   1 
ATOM   13301 C CA  . ALA D 1 346 ? -14.608 7.397   -77.326  1.00 21.65  ? 339  ALA D CA  1 
ATOM   13302 C C   . ALA D 1 346 ? -15.562 8.588   -77.190  1.00 21.53  ? 339  ALA D C   1 
ATOM   13303 O O   . ALA D 1 346 ? -16.738 8.321   -76.888  1.00 20.95  ? 339  ALA D O   1 
ATOM   13304 C CB  . ALA D 1 346 ? -13.684 7.245   -76.147  1.00 22.37  ? 339  ALA D CB  1 
ATOM   13305 N N   . CYS D 1 347 ? -15.087 9.829   -77.409  1.00 20.85  ? 340  CYS D N   1 
ATOM   13306 C CA  . CYS D 1 347 ? -15.894 11.077  -77.252  1.00 20.54  ? 340  CYS D CA  1 
ATOM   13307 C C   . CYS D 1 347 ? -17.078 11.050  -78.231  1.00 20.68  ? 340  CYS D C   1 
ATOM   13308 O O   . CYS D 1 347 ? -18.236 11.295  -77.805  1.00 21.47  ? 340  CYS D O   1 
ATOM   13309 C CB  . CYS D 1 347 ? -15.071 12.339  -77.477  1.00 20.14  ? 340  CYS D CB  1 
ATOM   13310 S SG  . CYS D 1 347 ? -13.917 12.717  -76.138  1.00 20.96  ? 340  CYS D SG  1 
ATOM   13311 N N   . ALA D 1 348 ? -16.796 10.740  -79.498  1.00 20.46  ? 341  ALA D N   1 
ATOM   13312 C CA  . ALA D 1 348 ? -17.814 10.550  -80.544  1.00 20.04  ? 341  ALA D CA  1 
ATOM   13313 C C   . ALA D 1 348 ? -18.876 9.574   -80.037  1.00 19.83  ? 341  ALA D C   1 
ATOM   13314 O O   . ALA D 1 348 ? -20.070 9.909   -80.153  1.00 18.79  ? 341  ALA D O   1 
ATOM   13315 C CB  . ALA D 1 348 ? -17.170 10.066  -81.815  1.00 21.27  ? 341  ALA D CB  1 
ATOM   13316 N N   . ALA D 1 349 ? -18.459 8.427   -79.490  1.00 19.52  ? 342  ALA D N   1 
ATOM   13317 C CA  . ALA D 1 349 ? -19.371 7.346   -79.033  1.00 19.37  ? 342  ALA D CA  1 
ATOM   13318 C C   . ALA D 1 349 ? -20.257 7.867   -77.898  1.00 18.82  ? 342  ALA D C   1 
ATOM   13319 O O   . ALA D 1 349 ? -21.484 7.612   -77.915  1.00 19.13  ? 342  ALA D O   1 
ATOM   13320 C CB  . ALA D 1 349 ? -18.584 6.125   -78.610  1.00 19.85  ? 342  ALA D CB  1 
ATOM   13321 N N   . ALA D 1 350 ? -19.666 8.592   -76.958  1.00 17.84  ? 343  ALA D N   1 
ATOM   13322 C CA  . ALA D 1 350 ? -20.378 9.138   -75.787  1.00 18.80  ? 343  ALA D CA  1 
ATOM   13323 C C   . ALA D 1 350 ? -21.351 10.219  -76.267  1.00 19.44  ? 343  ALA D C   1 
ATOM   13324 O O   . ALA D 1 350 ? -22.498 10.225  -75.759  1.00 19.12  ? 343  ALA D O   1 
ATOM   13325 C CB  . ALA D 1 350 ? -19.423 9.660   -74.739  1.00 18.15  ? 343  ALA D CB  1 
ATOM   13326 N N   . LEU D 1 351 ? -20.915 11.091  -77.181  1.00 18.57  ? 344  LEU D N   1 
ATOM   13327 C CA  . LEU D 1 351 ? -21.736 12.243  -77.634  1.00 19.78  ? 344  LEU D CA  1 
ATOM   13328 C C   . LEU D 1 351 ? -22.982 11.688  -78.325  1.00 19.14  ? 344  LEU D C   1 
ATOM   13329 O O   . LEU D 1 351 ? -24.106 12.211  -78.097  1.00 19.65  ? 344  LEU D O   1 
ATOM   13330 C CB  . LEU D 1 351 ? -20.902 13.116  -78.573  1.00 20.82  ? 344  LEU D CB  1 
ATOM   13331 C CG  . LEU D 1 351 ? -19.902 14.020  -77.854  1.00 22.62  ? 344  LEU D CG  1 
ATOM   13332 C CD1 . LEU D 1 351 ? -18.760 14.448  -78.770  1.00 23.28  ? 344  LEU D CD1 1 
ATOM   13333 C CD2 . LEU D 1 351 ? -20.600 15.233  -77.272  1.00 22.70  ? 344  LEU D CD2 1 
ATOM   13334 N N   . ALA D 1 352 ? -22.780 10.636  -79.116  1.00 19.89  ? 345  ALA D N   1 
ATOM   13335 C CA  . ALA D 1 352 ? -23.855 9.909   -79.820  1.00 21.27  ? 345  ALA D CA  1 
ATOM   13336 C C   . ALA D 1 352 ? -24.798 9.319   -78.782  1.00 21.94  ? 345  ALA D C   1 
ATOM   13337 O O   . ALA D 1 352 ? -25.998 9.496   -78.918  1.00 23.47  ? 345  ALA D O   1 
ATOM   13338 C CB  . ALA D 1 352 ? -23.286 8.838   -80.726  1.00 21.92  ? 345  ALA D CB  1 
ATOM   13339 N N   . THR D 1 353 ? -24.252 8.642   -77.777  1.00 24.08  ? 346  THR D N   1 
ATOM   13340 C CA  . THR D 1 353 ? -25.027 7.923   -76.734  1.00 22.61  ? 346  THR D CA  1 
ATOM   13341 C C   . THR D 1 353 ? -25.954 8.902   -76.024  1.00 21.72  ? 346  THR D C   1 
ATOM   13342 O O   . THR D 1 353 ? -27.134 8.583   -75.918  1.00 18.74  ? 346  THR D O   1 
ATOM   13343 C CB  . THR D 1 353 ? -24.099 7.219   -75.743  1.00 22.61  ? 346  THR D CB  1 
ATOM   13344 O OG1 . THR D 1 353 ? -23.220 6.391   -76.512  1.00 23.19  ? 346  THR D OG1 1 
ATOM   13345 C CG2 . THR D 1 353 ? -24.877 6.403   -74.735  1.00 23.30  ? 346  THR D CG2 1 
ATOM   13346 N N   . ILE D 1 354 ? -25.429 10.043  -75.577  1.00 22.28  ? 347  ILE D N   1 
ATOM   13347 C CA  . ILE D 1 354 ? -26.240 11.117  -74.930  1.00 22.71  ? 347  ILE D CA  1 
ATOM   13348 C C   . ILE D 1 354 ? -27.321 11.581  -75.899  1.00 23.45  ? 347  ILE D C   1 
ATOM   13349 O O   . ILE D 1 354 ? -28.483 11.702  -75.482  1.00 24.65  ? 347  ILE D O   1 
ATOM   13350 C CB  . ILE D 1 354 ? -25.366 12.303  -74.502  1.00 22.60  ? 347  ILE D CB  1 
ATOM   13351 C CG1 . ILE D 1 354 ? -24.470 11.915  -73.334  1.00 23.37  ? 347  ILE D CG1 1 
ATOM   13352 C CG2 . ILE D 1 354 ? -26.222 13.523  -74.172  1.00 22.76  ? 347  ILE D CG2 1 
ATOM   13353 C CD1 . ILE D 1 354 ? -23.222 12.763  -73.239  1.00 25.69  ? 347  ILE D CD1 1 
ATOM   13354 N N   . ASN D 1 355 ? -26.948 11.856  -77.151  1.00 24.67  ? 348  ASN D N   1 
ATOM   13355 C CA  . ASN D 1 355 ? -27.935 12.304  -78.163  1.00 21.96  ? 348  ASN D CA  1 
ATOM   13356 C C   . ASN D 1 355 ? -29.065 11.277  -78.255  1.00 21.24  ? 348  ASN D C   1 
ATOM   13357 O O   . ASN D 1 355 ? -30.232 11.701  -78.268  1.00 20.21  ? 348  ASN D O   1 
ATOM   13358 C CB  . ASN D 1 355 ? -27.320 12.526  -79.535  1.00 23.15  ? 348  ASN D CB  1 
ATOM   13359 C CG  . ASN D 1 355 ? -28.302 13.213  -80.455  1.00 23.48  ? 348  ASN D CG  1 
ATOM   13360 O OD1 . ASN D 1 355 ? -28.953 12.567  -81.267  1.00 25.13  ? 348  ASN D OD1 1 
ATOM   13361 N ND2 . ASN D 1 355 ? -28.488 14.507  -80.274  1.00 23.89  ? 348  ASN D ND2 1 
ATOM   13362 N N   . VAL D 1 356 ? -28.733 9.983   -78.325  1.00 20.84  ? 349  VAL D N   1 
ATOM   13363 C CA  . VAL D 1 356 ? -29.712 8.870   -78.510  1.00 22.72  ? 349  VAL D CA  1 
ATOM   13364 C C   . VAL D 1 356 ? -30.628 8.810   -77.289  1.00 22.78  ? 349  VAL D C   1 
ATOM   13365 O O   . VAL D 1 356 ? -31.849 8.774   -77.480  1.00 21.93  ? 349  VAL D O   1 
ATOM   13366 C CB  . VAL D 1 356 ? -29.008 7.523   -78.760  1.00 23.04  ? 349  VAL D CB  1 
ATOM   13367 C CG1 . VAL D 1 356 ? -29.917 6.319   -78.552  1.00 24.11  ? 349  VAL D CG1 1 
ATOM   13368 C CG2 . VAL D 1 356 ? -28.431 7.489   -80.159  1.00 23.25  ? 349  VAL D CG2 1 
ATOM   13369 N N   . LEU D 1 357 ? -30.059 8.793   -76.080  1.00 25.06  ? 350  LEU D N   1 
ATOM   13370 C CA  . LEU D 1 357 ? -30.833 8.629   -74.820  1.00 23.59  ? 350  LEU D CA  1 
ATOM   13371 C C   . LEU D 1 357 ? -31.867 9.756   -74.703  1.00 22.41  ? 350  LEU D C   1 
ATOM   13372 O O   . LEU D 1 357 ? -33.004 9.451   -74.320  1.00 21.20  ? 350  LEU D O   1 
ATOM   13373 C CB  . LEU D 1 357 ? -29.869 8.610   -73.626  1.00 23.83  ? 350  LEU D CB  1 
ATOM   13374 C CG  . LEU D 1 357 ? -29.018 7.349   -73.476  1.00 23.32  ? 350  LEU D CG  1 
ATOM   13375 C CD1 . LEU D 1 357 ? -27.895 7.591   -72.479  1.00 23.94  ? 350  LEU D CD1 1 
ATOM   13376 C CD2 . LEU D 1 357 ? -29.849 6.141   -73.054  1.00 23.74  ? 350  LEU D CD2 1 
ATOM   13377 N N   . LEU D 1 358 ? -31.476 10.991  -75.028  1.00 22.25  ? 351  LEU D N   1 
ATOM   13378 C CA  . LEU D 1 358 ? -32.340 12.191  -74.894  1.00 23.45  ? 351  LEU D CA  1 
ATOM   13379 C C   . LEU D 1 358 ? -33.390 12.208  -76.012  1.00 23.96  ? 351  LEU D C   1 
ATOM   13380 O O   . LEU D 1 358 ? -34.585 12.324  -75.679  1.00 21.51  ? 351  LEU D O   1 
ATOM   13381 C CB  . LEU D 1 358 ? -31.471 13.451  -74.909  1.00 23.38  ? 351  LEU D CB  1 
ATOM   13382 C CG  . LEU D 1 358 ? -30.569 13.616  -73.694  1.00 25.33  ? 351  LEU D CG  1 
ATOM   13383 C CD1 . LEU D 1 358 ? -29.800 14.934  -73.751  1.00 25.88  ? 351  LEU D CD1 1 
ATOM   13384 C CD2 . LEU D 1 358 ? -31.379 13.508  -72.401  1.00 25.62  ? 351  LEU D CD2 1 
ATOM   13385 N N   . GLU D 1 359 ? -32.967 12.072  -77.272  1.00 27.19  ? 352  GLU D N   1 
ATOM   13386 C CA  . GLU D 1 359 ? -33.860 12.090  -78.464  1.00 30.60  ? 352  GLU D CA  1 
ATOM   13387 C C   . GLU D 1 359 ? -34.996 11.091  -78.303  1.00 30.28  ? 352  GLU D C   1 
ATOM   13388 O O   . GLU D 1 359 ? -36.128 11.481  -78.612  1.00 34.28  ? 352  GLU D O   1 
ATOM   13389 C CB  . GLU D 1 359 ? -33.170 11.698  -79.768  1.00 36.14  ? 352  GLU D CB  1 
ATOM   13390 C CG  . GLU D 1 359 ? -32.454 12.844  -80.461  1.00 44.00  ? 352  GLU D CG  1 
ATOM   13391 C CD  . GLU D 1 359 ? -33.269 13.879  -81.230  1.00 48.30  ? 352  GLU D CD  1 
ATOM   13392 O OE1 . GLU D 1 359 ? -34.491 14.067  -80.957  1.00 50.06  ? 352  GLU D OE1 1 
ATOM   13393 O OE2 . GLU D 1 359 ? -32.656 14.510  -82.091  1.00 52.05  ? 352  GLU D OE2 1 
ATOM   13394 N N   . GLN D 1 360 ? -34.697 9.862   -77.868  1.00 29.07  ? 353  GLN D N   1 
ATOM   13395 C CA  . GLN D 1 360 ? -35.670 8.740   -77.807  1.00 29.31  ? 353  GLN D CA  1 
ATOM   13396 C C   . GLN D 1 360 ? -36.246 8.538   -76.408  1.00 28.66  ? 353  GLN D C   1 
ATOM   13397 O O   . GLN D 1 360 ? -36.989 7.570   -76.246  1.00 27.63  ? 353  GLN D O   1 
ATOM   13398 C CB  . GLN D 1 360 ? -35.013 7.433   -78.217  1.00 29.43  ? 353  GLN D CB  1 
ATOM   13399 C CG  . GLN D 1 360 ? -34.438 7.468   -79.618  1.00 32.29  ? 353  GLN D CG  1 
ATOM   13400 C CD  . GLN D 1 360 ? -33.965 6.083   -79.985  1.00 35.41  ? 353  GLN D CD  1 
ATOM   13401 O OE1 . GLN D 1 360 ? -34.572 5.085   -79.580  1.00 34.50  ? 353  GLN D OE1 1 
ATOM   13402 N NE2 . GLN D 1 360 ? -32.845 6.015   -80.702  1.00 36.55  ? 353  GLN D NE2 1 
ATOM   13403 N N   . ASN D 1 361 ? -35.933 9.405   -75.446  1.00 31.08  ? 354  ASN D N   1 
ATOM   13404 C CA  . ASN D 1 361 ? -36.472 9.345   -74.056  1.00 33.30  ? 354  ASN D CA  1 
ATOM   13405 C C   . ASN D 1 361 ? -36.303 7.927   -73.498  1.00 29.95  ? 354  ASN D C   1 
ATOM   13406 O O   . ASN D 1 361 ? -37.244 7.430   -72.875  1.00 29.19  ? 354  ASN D O   1 
ATOM   13407 C CB  . ASN D 1 361 ? -37.963 9.724   -73.990  1.00 41.66  ? 354  ASN D CB  1 
ATOM   13408 C CG  . ASN D 1 361 ? -38.269 11.183  -74.254  1.00 47.99  ? 354  ASN D CG  1 
ATOM   13409 O OD1 . ASN D 1 361 ? -38.418 11.962  -73.301  1.00 54.45  ? 354  ASN D OD1 1 
ATOM   13410 N ND2 . ASN D 1 361 ? -38.515 11.522  -75.516  1.00 46.63  ? 354  ASN D ND2 1 
ATOM   13411 N N   . LEU D 1 362 ? -35.136 7.303   -73.683  1.00 28.28  ? 355  LEU D N   1 
ATOM   13412 C CA  . LEU D 1 362 ? -34.881 5.914   -73.216  1.00 27.02  ? 355  LEU D CA  1 
ATOM   13413 C C   . LEU D 1 362 ? -34.886 5.815   -71.685  1.00 27.77  ? 355  LEU D C   1 
ATOM   13414 O O   . LEU D 1 362 ? -35.205 4.753   -71.151  1.00 26.18  ? 355  LEU D O   1 
ATOM   13415 C CB  . LEU D 1 362 ? -33.564 5.425   -73.814  1.00 27.10  ? 355  LEU D CB  1 
ATOM   13416 C CG  . LEU D 1 362 ? -33.699 4.825   -75.211  1.00 25.95  ? 355  LEU D CG  1 
ATOM   13417 C CD1 . LEU D 1 362 ? -32.340 4.764   -75.918  1.00 29.85  ? 355  LEU D CD1 1 
ATOM   13418 C CD2 . LEU D 1 362 ? -34.311 3.439   -75.135  1.00 23.96  ? 355  LEU D CD2 1 
ATOM   13419 N N   . PRO D 1 363 ? -34.536 6.874   -70.905  1.00 26.78  ? 356  PRO D N   1 
ATOM   13420 C CA  . PRO D 1 363 ? -34.759 6.851   -69.462  1.00 25.66  ? 356  PRO D CA  1 
ATOM   13421 C C   . PRO D 1 363 ? -36.220 6.526   -69.135  1.00 25.73  ? 356  PRO D C   1 
ATOM   13422 O O   . PRO D 1 363 ? -36.483 5.607   -68.381  1.00 25.34  ? 356  PRO D O   1 
ATOM   13423 C CB  . PRO D 1 363 ? -34.333 8.259   -69.012  1.00 26.32  ? 356  PRO D CB  1 
ATOM   13424 C CG  . PRO D 1 363 ? -33.285 8.645   -70.017  1.00 25.83  ? 356  PRO D CG  1 
ATOM   13425 C CD  . PRO D 1 363 ? -33.828 8.097   -71.323  1.00 27.46  ? 356  PRO D CD  1 
ATOM   13426 N N   . ALA D 1 364 ? -37.150 7.252   -69.740  1.00 25.91  ? 357  ALA D N   1 
ATOM   13427 C CA  . ALA D 1 364 ? -38.591 7.002   -69.556  1.00 24.59  ? 357  ALA D CA  1 
ATOM   13428 C C   . ALA D 1 364 ? -38.915 5.554   -69.959  1.00 24.47  ? 357  ALA D C   1 
ATOM   13429 O O   . ALA D 1 364 ? -39.703 4.920   -69.245  1.00 26.86  ? 357  ALA D O   1 
ATOM   13430 C CB  . ALA D 1 364 ? -39.374 8.015   -70.339  1.00 24.19  ? 357  ALA D CB  1 
ATOM   13431 N N   . GLN D 1 365 ? -38.320 5.028   -71.035  1.00 23.36  ? 358  GLN D N   1 
ATOM   13432 C CA  . GLN D 1 365 ? -38.612 3.646   -71.499  1.00 24.33  ? 358  GLN D CA  1 
ATOM   13433 C C   . GLN D 1 365 ? -38.130 2.649   -70.445  1.00 24.34  ? 358  GLN D C   1 
ATOM   13434 O O   . GLN D 1 365 ? -38.825 1.656   -70.198  1.00 23.38  ? 358  GLN D O   1 
ATOM   13435 C CB  . GLN D 1 365 ? -37.960 3.345   -72.849  1.00 25.69  ? 358  GLN D CB  1 
ATOM   13436 C CG  . GLN D 1 365 ? -38.568 4.121   -73.997  1.00 27.50  ? 358  GLN D CG  1 
ATOM   13437 C CD  . GLN D 1 365 ? -38.013 3.696   -75.338  1.00 29.36  ? 358  GLN D CD  1 
ATOM   13438 O OE1 . GLN D 1 365 ? -37.930 2.518   -75.696  1.00 29.78  ? 358  GLN D OE1 1 
ATOM   13439 N NE2 . GLN D 1 365 ? -37.642 4.683   -76.127  1.00 29.83  ? 358  GLN D NE2 1 
ATOM   13440 N N   . ALA D 1 366 ? -36.967 2.898   -69.861  1.00 25.32  ? 359  ALA D N   1 
ATOM   13441 C CA  . ALA D 1 366 ? -36.348 2.009   -68.855  1.00 26.69  ? 359  ALA D CA  1 
ATOM   13442 C C   . ALA D 1 366 ? -37.298 1.891   -67.670  1.00 28.30  ? 359  ALA D C   1 
ATOM   13443 O O   . ALA D 1 366 ? -37.528 0.759   -67.194  1.00 28.11  ? 359  ALA D O   1 
ATOM   13444 C CB  . ALA D 1 366 ? -35.000 2.536   -68.438  1.00 26.00  ? 359  ALA D CB  1 
ATOM   13445 N N   . GLU D 1 367 ? -37.857 3.021   -67.239  1.00 31.92  ? 360  GLU D N   1 
ATOM   13446 C CA  . GLU D 1 367 ? -38.869 3.078   -66.151  1.00 33.45  ? 360  GLU D CA  1 
ATOM   13447 C C   . GLU D 1 367 ? -40.037 2.145   -66.491  1.00 29.45  ? 360  GLU D C   1 
ATOM   13448 O O   . GLU D 1 367 ? -40.347 1.262   -65.665  1.00 26.05  ? 360  GLU D O   1 
ATOM   13449 C CB  . GLU D 1 367 ? -39.370 4.508   -65.945  1.00 36.90  ? 360  GLU D CB  1 
ATOM   13450 C CG  . GLU D 1 367 ? -40.209 4.659   -64.688  1.00 38.13  ? 360  GLU D CG  1 
ATOM   13451 C CD  . GLU D 1 367 ? -40.886 6.000   -64.514  1.00 44.28  ? 360  GLU D CD  1 
ATOM   13452 O OE1 . GLU D 1 367 ? -40.534 6.944   -65.261  1.00 51.35  ? 360  GLU D OE1 1 
ATOM   13453 O OE2 . GLU D 1 367 ? -41.770 6.093   -63.626  1.00 51.91  ? 360  GLU D OE2 1 
ATOM   13454 N N   . GLN D 1 368 ? -40.649 2.330   -67.662  1.00 29.10  ? 361  GLN D N   1 
ATOM   13455 C CA  . GLN D 1 368 ? -41.883 1.608   -68.065  1.00 31.39  ? 361  GLN D CA  1 
ATOM   13456 C C   . GLN D 1 368 ? -41.557 0.121   -68.175  1.00 27.65  ? 361  GLN D C   1 
ATOM   13457 O O   . GLN D 1 368 ? -42.289 -0.692  -67.612  1.00 24.99  ? 361  GLN D O   1 
ATOM   13458 C CB  . GLN D 1 368 ? -42.444 2.120   -69.388  1.00 37.40  ? 361  GLN D CB  1 
ATOM   13459 C CG  . GLN D 1 368 ? -43.901 1.737   -69.559  1.00 48.04  ? 361  GLN D CG  1 
ATOM   13460 C CD  . GLN D 1 368 ? -44.323 1.546   -70.994  1.00 60.52  ? 361  GLN D CD  1 
ATOM   13461 O OE1 . GLN D 1 368 ? -43.584 1.029   -71.842  1.00 69.02  ? 361  GLN D OE1 1 
ATOM   13462 N NE2 . GLN D 1 368 ? -45.558 1.938   -71.268  1.00 67.19  ? 361  GLN D NE2 1 
ATOM   13463 N N   . LYS D 1 369 ? -40.472 -0.208  -68.860  1.00 26.75  ? 362  LYS D N   1 
ATOM   13464 C CA  . LYS D 1 369 ? -40.125 -1.606  -69.207  1.00 26.66  ? 362  LYS D CA  1 
ATOM   13465 C C   . LYS D 1 369 ? -39.624 -2.324  -67.961  1.00 24.61  ? 362  LYS D C   1 
ATOM   13466 O O   . LYS D 1 369 ? -39.933 -3.512  -67.811  1.00 23.79  ? 362  LYS D O   1 
ATOM   13467 C CB  . LYS D 1 369 ? -39.111 -1.629  -70.349  1.00 26.79  ? 362  LYS D CB  1 
ATOM   13468 C CG  . LYS D 1 369 ? -39.667 -1.152  -71.688  1.00 27.15  ? 362  LYS D CG  1 
ATOM   13469 C CD  . LYS D 1 369 ? -38.593 -0.896  -72.709  1.00 28.17  ? 362  LYS D CD  1 
ATOM   13470 C CE  . LYS D 1 369 ? -39.105 -0.356  -74.020  1.00 29.48  ? 362  LYS D CE  1 
ATOM   13471 N NZ  . LYS D 1 369 ? -38.038 -0.310  -75.052  1.00 30.95  ? 362  LYS D NZ  1 
ATOM   13472 N N   . GLY D 1 370 ? -38.881 -1.620  -67.112  1.00 23.74  ? 363  GLY D N   1 
ATOM   13473 C CA  . GLY D 1 370 ? -38.423 -2.134  -65.808  1.00 24.36  ? 363  GLY D CA  1 
ATOM   13474 C C   . GLY D 1 370 ? -39.589 -2.442  -64.897  1.00 24.06  ? 363  GLY D C   1 
ATOM   13475 O O   . GLY D 1 370 ? -39.612 -3.521  -64.293  1.00 23.74  ? 363  GLY D O   1 
ATOM   13476 N N   . ASP D 1 371 ? -40.537 -1.520  -64.803  1.00 24.83  ? 364  ASP D N   1 
ATOM   13477 C CA  . ASP D 1 371 ? -41.779 -1.726  -64.022  1.00 26.55  ? 364  ASP D CA  1 
ATOM   13478 C C   . ASP D 1 371 ? -42.475 -2.995  -64.521  1.00 23.66  ? 364  ASP D C   1 
ATOM   13479 O O   . ASP D 1 371 ? -42.905 -3.826  -63.690  1.00 24.61  ? 364  ASP D O   1 
ATOM   13480 C CB  . ASP D 1 371 ? -42.689 -0.497  -64.090  1.00 29.33  ? 364  ASP D CB  1 
ATOM   13481 C CG  . ASP D 1 371 ? -42.193 0.684   -63.257  1.00 31.59  ? 364  ASP D CG  1 
ATOM   13482 O OD1 . ASP D 1 371 ? -41.152 0.534   -62.550  1.00 31.41  ? 364  ASP D OD1 1 
ATOM   13483 O OD2 . ASP D 1 371 ? -42.833 1.764   -63.344  1.00 30.54  ? 364  ASP D OD2 1 
ATOM   13484 N N   A MET D 1 372 ? -42.578 -3.137  -65.838  0.51 23.45  ? 365  MET D N   1 
ATOM   13485 N N   B MET D 1 372 ? -42.601 -3.152  -65.833  0.49 21.86  ? 365  MET D N   1 
ATOM   13486 C CA  A MET D 1 372 ? -43.248 -4.279  -66.507  0.51 24.85  ? 365  MET D CA  1 
ATOM   13487 C CA  B MET D 1 372 ? -43.294 -4.330  -66.396  0.49 22.05  ? 365  MET D CA  1 
ATOM   13488 C C   A MET D 1 372 ? -42.494 -5.567  -66.165  0.51 22.81  ? 365  MET D C   1 
ATOM   13489 C C   B MET D 1 372 ? -42.471 -5.572  -66.046  0.49 21.08  ? 365  MET D C   1 
ATOM   13490 O O   A MET D 1 372 ? -43.123 -6.505  -65.687  0.51 21.75  ? 365  MET D O   1 
ATOM   13491 O O   B MET D 1 372 ? -43.010 -6.468  -65.391  0.49 19.51  ? 365  MET D O   1 
ATOM   13492 C CB  A MET D 1 372 ? -43.283 -4.060  -68.022  0.51 27.83  ? 365  MET D CB  1 
ATOM   13493 C CB  B MET D 1 372 ? -43.496 -4.201  -67.908  0.49 22.63  ? 365  MET D CB  1 
ATOM   13494 C CG  A MET D 1 372 ? -43.961 -5.169  -68.799  0.51 29.63  ? 365  MET D CG  1 
ATOM   13495 C CG  B MET D 1 372 ? -44.255 -5.364  -68.519  0.49 22.53  ? 365  MET D CG  1 
ATOM   13496 S SD  A MET D 1 372 ? -44.244 -4.742  -70.535  0.51 33.84  ? 365  MET D SD  1 
ATOM   13497 S SD  B MET D 1 372 ? -43.110 -6.620  -69.157  0.49 22.71  ? 365  MET D SD  1 
ATOM   13498 C CE  A MET D 1 372 ? -42.769 -3.823  -70.961  0.51 33.25  ? 365  MET D CE  1 
ATOM   13499 C CE  B MET D 1 372 ? -44.226 -7.617  -70.139  0.49 23.14  ? 365  MET D CE  1 
ATOM   13500 N N   . LEU D 1 373 ? -41.185 -5.584  -66.390  1.00 22.57  ? 366  LEU D N   1 
ATOM   13501 C CA  . LEU D 1 373 ? -40.311 -6.769  -66.157  1.00 22.49  ? 366  LEU D CA  1 
ATOM   13502 C C   . LEU D 1 373 ? -40.272 -7.146  -64.674  1.00 23.26  ? 366  LEU D C   1 
ATOM   13503 O O   . LEU D 1 373 ? -40.359 -8.353  -64.374  1.00 24.08  ? 366  LEU D O   1 
ATOM   13504 C CB  . LEU D 1 373 ? -38.904 -6.460  -66.655  1.00 22.44  ? 366  LEU D CB  1 
ATOM   13505 C CG  . LEU D 1 373 ? -38.708 -6.584  -68.161  1.00 21.80  ? 366  LEU D CG  1 
ATOM   13506 C CD1 . LEU D 1 373 ? -37.276 -6.204  -68.502  1.00 21.68  ? 366  LEU D CD1 1 
ATOM   13507 C CD2 . LEU D 1 373 ? -39.041 -7.994  -68.655  1.00 21.35  ? 366  LEU D CD2 1 
ATOM   13508 N N   . LEU D 1 374 ? -40.132 -6.166  -63.781  1.00 22.85  ? 367  LEU D N   1 
ATOM   13509 C CA  . LEU D 1 374 ? -40.065 -6.411  -62.322  1.00 23.11  ? 367  LEU D CA  1 
ATOM   13510 C C   . LEU D 1 374 ? -41.392 -7.032  -61.860  1.00 23.26  ? 367  LEU D C   1 
ATOM   13511 O O   . LEU D 1 374 ? -41.332 -8.018  -61.086  1.00 22.67  ? 367  LEU D O   1 
ATOM   13512 C CB  . LEU D 1 374 ? -39.761 -5.094  -61.608  1.00 23.61  ? 367  LEU D CB  1 
ATOM   13513 C CG  . LEU D 1 374 ? -39.573 -5.193  -60.100  1.00 25.54  ? 367  LEU D CG  1 
ATOM   13514 C CD1 . LEU D 1 374 ? -38.541 -6.255  -59.736  1.00 26.11  ? 367  LEU D CD1 1 
ATOM   13515 C CD2 . LEU D 1 374 ? -39.188 -3.835  -59.535  1.00 26.47  ? 367  LEU D CD2 1 
ATOM   13516 N N   . ASP D 1 375 ? -42.529 -6.500  -62.332  1.00 23.45  ? 368  ASP D N   1 
ATOM   13517 C CA  . ASP D 1 375 ? -43.876 -7.047  -62.027  1.00 26.20  ? 368  ASP D CA  1 
ATOM   13518 C C   . ASP D 1 375 ? -43.876 -8.510  -62.452  1.00 25.44  ? 368  ASP D C   1 
ATOM   13519 O O   . ASP D 1 375 ? -44.250 -9.361  -61.654  1.00 26.18  ? 368  ASP D O   1 
ATOM   13520 C CB  . ASP D 1 375 ? -45.025 -6.288  -62.710  1.00 29.23  ? 368  ASP D CB  1 
ATOM   13521 C CG  . ASP D 1 375 ? -46.449 -6.821  -62.412  1.00 31.60  ? 368  ASP D CG  1 
ATOM   13522 O OD1 . ASP D 1 375 ? -46.859 -6.775  -61.226  1.00 31.42  ? 368  ASP D OD1 1 
ATOM   13523 O OD2 . ASP D 1 375 ? -47.179 -7.270  -63.372  1.00 28.89  ? 368  ASP D OD2 1 
ATOM   13524 N N   . GLY D 1 376 ? -43.439 -8.781  -63.673  1.00 25.94  ? 369  GLY D N   1 
ATOM   13525 C CA  . GLY D 1 376 ? -43.335 -10.157 -64.193  1.00 26.93  ? 369  GLY D CA  1 
ATOM   13526 C C   . GLY D 1 376 ? -42.549 -11.051 -63.253  1.00 26.39  ? 369  GLY D C   1 
ATOM   13527 O O   . GLY D 1 376 ? -43.039 -12.142 -62.939  1.00 28.40  ? 369  GLY D O   1 
ATOM   13528 N N   . PHE D 1 377 ? -41.383 -10.596 -62.805  1.00 24.50  ? 370  PHE D N   1 
ATOM   13529 C CA  . PHE D 1 377 ? -40.457 -11.403 -61.980  1.00 24.02  ? 370  PHE D CA  1 
ATOM   13530 C C   . PHE D 1 377 ? -41.046 -11.603 -60.588  1.00 23.54  ? 370  PHE D C   1 
ATOM   13531 O O   . PHE D 1 377 ? -41.020 -12.751 -60.099  1.00 24.51  ? 370  PHE D O   1 
ATOM   13532 C CB  . PHE D 1 377 ? -39.080 -10.749 -61.906  1.00 24.42  ? 370  PHE D CB  1 
ATOM   13533 C CG  . PHE D 1 377 ? -38.348 -10.735 -63.219  1.00 24.23  ? 370  PHE D CG  1 
ATOM   13534 C CD1 . PHE D 1 377 ? -38.347 -11.857 -64.039  1.00 23.72  ? 370  PHE D CD1 1 
ATOM   13535 C CD2 . PHE D 1 377 ? -37.647 -9.611  -63.632  1.00 24.99  ? 370  PHE D CD2 1 
ATOM   13536 C CE1 . PHE D 1 377 ? -37.675 -11.850 -65.251  1.00 22.72  ? 370  PHE D CE1 1 
ATOM   13537 C CE2 . PHE D 1 377 ? -36.999 -9.605  -64.859  1.00 24.06  ? 370  PHE D CE2 1 
ATOM   13538 C CZ  . PHE D 1 377 ? -37.017 -10.721 -65.663  1.00 22.91  ? 370  PHE D CZ  1 
ATOM   13539 N N   A ARG D 1 378 ? -41.545 -10.526 -59.972  0.48 23.06  ? 371  ARG D N   1 
ATOM   13540 N N   B ARG D 1 378 ? -41.570 -10.533 -59.977  0.52 22.48  ? 371  ARG D N   1 
ATOM   13541 C CA  A ARG D 1 378 ? -42.210 -10.578 -58.644  0.48 23.14  ? 371  ARG D CA  1 
ATOM   13542 C CA  B ARG D 1 378 ? -42.219 -10.586 -58.636  0.52 22.21  ? 371  ARG D CA  1 
ATOM   13543 C C   A ARG D 1 378 ? -43.325 -11.633 -58.679  0.48 21.99  ? 371  ARG D C   1 
ATOM   13544 C C   B ARG D 1 378 ? -43.354 -11.616 -58.667  0.52 21.43  ? 371  ARG D C   1 
ATOM   13545 O O   A ARG D 1 378 ? -43.470 -12.373 -57.693  0.48 20.60  ? 371  ARG D O   1 
ATOM   13546 O O   B ARG D 1 378 ? -43.529 -12.331 -57.675  0.52 20.10  ? 371  ARG D O   1 
ATOM   13547 C CB  A ARG D 1 378 ? -42.742 -9.192  -58.257  0.48 23.88  ? 371  ARG D CB  1 
ATOM   13548 C CB  B ARG D 1 378 ? -42.654 -9.184  -58.183  0.52 22.28  ? 371  ARG D CB  1 
ATOM   13549 C CG  A ARG D 1 378 ? -41.701 -8.228  -57.707  0.48 24.71  ? 371  ARG D CG  1 
ATOM   13550 C CG  B ARG D 1 378 ? -41.476 -8.308  -57.767  0.52 22.36  ? 371  ARG D CG  1 
ATOM   13551 C CD  A ARG D 1 378 ? -42.358 -7.152  -56.860  0.48 24.56  ? 371  ARG D CD  1 
ATOM   13552 C CD  B ARG D 1 378 ? -41.785 -7.006  -57.050  0.52 21.41  ? 371  ARG D CD  1 
ATOM   13553 N NE  A ARG D 1 378 ? -41.456 -6.070  -56.467  0.48 24.56  ? 371  ARG D NE  1 
ATOM   13554 N NE  B ARG D 1 378 ? -42.533 -7.187  -55.816  0.52 20.87  ? 371  ARG D NE  1 
ATOM   13555 C CZ  A ARG D 1 378 ? -41.551 -4.797  -56.858  0.48 24.89  ? 371  ARG D CZ  1 
ATOM   13556 C CZ  B ARG D 1 378 ? -42.032 -7.521  -54.631  0.52 19.41  ? 371  ARG D CZ  1 
ATOM   13557 N NH1 A ARG D 1 378 ? -42.525 -4.408  -57.666  0.48 25.17  ? 371  ARG D NH1 1 
ATOM   13558 N NH1 B ARG D 1 378 ? -40.737 -7.738  -54.470  0.52 20.61  ? 371  ARG D NH1 1 
ATOM   13559 N NH2 A ARG D 1 378 ? -40.674 -3.914  -56.413  0.48 24.90  ? 371  ARG D NH2 1 
ATOM   13560 N NH2 B ARG D 1 378 ? -42.846 -7.646  -53.605  0.52 18.00  ? 371  ARG D NH2 1 
ATOM   13561 N N   . GLN D 1 379 ? -44.068 -11.714 -59.786  1.00 22.79  ? 372  GLN D N   1 
ATOM   13562 C CA  . GLN D 1 379 ? -45.181 -12.683 -59.953  1.00 24.92  ? 372  GLN D CA  1 
ATOM   13563 C C   . GLN D 1 379 ? -44.609 -14.101 -60.010  1.00 26.34  ? 372  GLN D C   1 
ATOM   13564 O O   . GLN D 1 379 ? -45.130 -14.971 -59.321  1.00 30.38  ? 372  GLN D O   1 
ATOM   13565 C CB  . GLN D 1 379 ? -46.012 -12.353 -61.191  1.00 25.46  ? 372  GLN D CB  1 
ATOM   13566 C CG  . GLN D 1 379 ? -47.225 -13.253 -61.377  1.00 26.67  ? 372  GLN D CG  1 
ATOM   13567 C CD  . GLN D 1 379 ? -48.103 -13.379 -60.152  1.00 27.44  ? 372  GLN D CD  1 
ATOM   13568 O OE1 . GLN D 1 379 ? -48.248 -12.446 -59.364  1.00 28.11  ? 372  GLN D OE1 1 
ATOM   13569 N NE2 . GLN D 1 379 ? -48.701 -14.551 -59.985  1.00 27.83  ? 372  GLN D NE2 1 
ATOM   13570 N N   . LEU D 1 380 ? -43.552 -14.320 -60.776  1.00 27.55  ? 373  LEU D N   1 
ATOM   13571 C CA  . LEU D 1 380 ? -42.856 -15.640 -60.850  1.00 28.60  ? 373  LEU D CA  1 
ATOM   13572 C C   . LEU D 1 380 ? -42.273 -16.010 -59.485  1.00 28.60  ? 373  LEU D C   1 
ATOM   13573 O O   . LEU D 1 380 ? -42.212 -17.224 -59.177  1.00 30.45  ? 373  LEU D O   1 
ATOM   13574 C CB  . LEU D 1 380 ? -41.772 -15.584 -61.926  1.00 28.07  ? 373  LEU D CB  1 
ATOM   13575 C CG  . LEU D 1 380 ? -42.299 -15.544 -63.360  1.00 28.74  ? 373  LEU D CG  1 
ATOM   13576 C CD1 . LEU D 1 380 ? -41.148 -15.413 -64.359  1.00 28.97  ? 373  LEU D CD1 1 
ATOM   13577 C CD2 . LEU D 1 380 ? -43.159 -16.769 -63.648  1.00 27.66  ? 373  LEU D CD2 1 
ATOM   13578 N N   . ALA D 1 381 ? -41.900 -15.010 -58.685  1.00 27.89  ? 374  ALA D N   1 
ATOM   13579 C CA  . ALA D 1 381 ? -41.384 -15.214 -57.317  1.00 28.00  ? 374  ALA D CA  1 
ATOM   13580 C C   . ALA D 1 381 ? -42.517 -15.755 -56.449  1.00 29.13  ? 374  ALA D C   1 
ATOM   13581 O O   . ALA D 1 381 ? -42.276 -16.732 -55.717  1.00 28.07  ? 374  ALA D O   1 
ATOM   13582 C CB  . ALA D 1 381 ? -40.819 -13.927 -56.765  1.00 28.37  ? 374  ALA D CB  1 
ATOM   13583 N N   . ARG D 1 382 ? -43.700 -15.129 -56.540  1.00 29.81  ? 375  ARG D N   1 
ATOM   13584 C CA  . ARG D 1 382 ? -44.934 -15.582 -55.844  1.00 28.61  ? 375  ARG D CA  1 
ATOM   13585 C C   . ARG D 1 382 ? -45.213 -17.033 -56.221  1.00 27.75  ? 375  ARG D C   1 
ATOM   13586 O O   . ARG D 1 382 ? -45.569 -17.811 -55.343  1.00 28.54  ? 375  ARG D O   1 
ATOM   13587 C CB  . ARG D 1 382 ? -46.133 -14.685 -56.163  1.00 29.82  ? 375  ARG D CB  1 
ATOM   13588 C CG  . ARG D 1 382 ? -46.269 -13.564 -55.155  1.00 31.69  ? 375  ARG D CG  1 
ATOM   13589 C CD  . ARG D 1 382 ? -47.453 -12.652 -55.332  1.00 33.79  ? 375  ARG D CD  1 
ATOM   13590 N NE  . ARG D 1 382 ? -46.917 -11.295 -55.290  1.00 37.11  ? 375  ARG D NE  1 
ATOM   13591 C CZ  . ARG D 1 382 ? -46.721 -10.511 -56.359  1.00 37.32  ? 375  ARG D CZ  1 
ATOM   13592 N NH1 . ARG D 1 382 ? -47.056 -10.940 -57.574  1.00 38.20  ? 375  ARG D NH1 1 
ATOM   13593 N NH2 . ARG D 1 382 ? -46.209 -9.295  -56.197  1.00 34.91  ? 375  ARG D NH2 1 
ATOM   13594 N N   . GLU D 1 383 ? -45.011 -17.385 -57.483  1.00 28.61  ? 376  GLU D N   1 
ATOM   13595 C CA  . GLU D 1 383 ? -45.392 -18.712 -58.028  1.00 32.04  ? 376  GLU D CA  1 
ATOM   13596 C C   . GLU D 1 383 ? -44.345 -19.762 -57.653  1.00 33.63  ? 376  GLU D C   1 
ATOM   13597 O O   . GLU D 1 383 ? -44.730 -20.938 -57.515  1.00 33.24  ? 376  GLU D O   1 
ATOM   13598 C CB  . GLU D 1 383 ? -45.616 -18.583 -59.530  1.00 33.35  ? 376  GLU D CB  1 
ATOM   13599 C CG  . GLU D 1 383 ? -46.732 -17.600 -59.838  1.00 35.79  ? 376  GLU D CG  1 
ATOM   13600 C CD  . GLU D 1 383 ? -47.266 -17.626 -61.248  1.00 38.58  ? 376  GLU D CD  1 
ATOM   13601 O OE1 . GLU D 1 383 ? -47.173 -18.691 -61.863  1.00 42.91  ? 376  GLU D OE1 1 
ATOM   13602 O OE2 . GLU D 1 383 ? -47.755 -16.579 -61.721  1.00 43.82  ? 376  GLU D OE2 1 
ATOM   13603 N N   . TYR D 1 384 ? -43.075 -19.364 -57.489  1.00 34.67  ? 377  TYR D N   1 
ATOM   13604 C CA  . TYR D 1 384 ? -41.945 -20.302 -57.280  1.00 30.46  ? 377  TYR D CA  1 
ATOM   13605 C C   . TYR D 1 384 ? -41.137 -19.862 -56.073  1.00 31.65  ? 377  TYR D C   1 
ATOM   13606 O O   . TYR D 1 384 ? -39.964 -19.511 -56.183  1.00 32.72  ? 377  TYR D O   1 
ATOM   13607 C CB  . TYR D 1 384 ? -41.107 -20.390 -58.550  1.00 31.79  ? 377  TYR D CB  1 
ATOM   13608 C CG  . TYR D 1 384 ? -41.820 -20.995 -59.737  1.00 30.19  ? 377  TYR D CG  1 
ATOM   13609 C CD1 . TYR D 1 384 ? -41.839 -22.368 -59.932  1.00 29.96  ? 377  TYR D CD1 1 
ATOM   13610 C CD2 . TYR D 1 384 ? -42.464 -20.197 -60.669  1.00 29.41  ? 377  TYR D CD2 1 
ATOM   13611 C CE1 . TYR D 1 384 ? -42.470 -22.934 -61.024  1.00 30.30  ? 377  TYR D CE1 1 
ATOM   13612 C CE2 . TYR D 1 384 ? -43.104 -20.750 -61.763  1.00 31.09  ? 377  TYR D CE2 1 
ATOM   13613 C CZ  . TYR D 1 384 ? -43.117 -22.122 -61.931  1.00 31.40  ? 377  TYR D CZ  1 
ATOM   13614 O OH  . TYR D 1 384 ? -43.753 -22.691 -62.993  1.00 33.63  ? 377  TYR D OH  1 
ATOM   13615 N N   . PRO D 1 385 ? -41.753 -19.872 -54.873  1.00 30.95  ? 378  PRO D N   1 
ATOM   13616 C CA  . PRO D 1 385 ? -41.038 -19.557 -53.635  1.00 31.76  ? 378  PRO D CA  1 
ATOM   13617 C C   . PRO D 1 385 ? -40.076 -20.665 -53.187  1.00 31.95  ? 378  PRO D C   1 
ATOM   13618 O O   . PRO D 1 385 ? -39.227 -20.405 -52.360  1.00 36.85  ? 378  PRO D O   1 
ATOM   13619 C CB  . PRO D 1 385 ? -42.176 -19.435 -52.621  1.00 32.15  ? 378  PRO D CB  1 
ATOM   13620 C CG  . PRO D 1 385 ? -43.232 -20.383 -53.158  1.00 31.37  ? 378  PRO D CG  1 
ATOM   13621 C CD  . PRO D 1 385 ? -43.165 -20.203 -54.654  1.00 31.06  ? 378  PRO D CD  1 
ATOM   13622 N N   . ASP D 1 386 ? -40.252 -21.869 -53.731  1.00 30.92  ? 379  ASP D N   1 
ATOM   13623 C CA  . ASP D 1 386 ? -39.358 -23.044 -53.536  1.00 31.64  ? 379  ASP D CA  1 
ATOM   13624 C C   . ASP D 1 386 ? -37.990 -22.794 -54.210  1.00 31.79  ? 379  ASP D C   1 
ATOM   13625 O O   . ASP D 1 386 ? -36.999 -23.439 -53.824  1.00 25.15  ? 379  ASP D O   1 
ATOM   13626 C CB  . ASP D 1 386 ? -40.034 -24.302 -54.086  1.00 32.90  ? 379  ASP D CB  1 
ATOM   13627 C CG  . ASP D 1 386 ? -40.566 -24.153 -55.507  1.00 34.24  ? 379  ASP D CG  1 
ATOM   13628 O OD1 . ASP D 1 386 ? -41.144 -23.083 -55.827  1.00 34.61  ? 379  ASP D OD1 1 
ATOM   13629 O OD2 . ASP D 1 386 ? -40.413 -25.113 -56.286  1.00 37.90  ? 379  ASP D OD2 1 
ATOM   13630 N N   . LEU D 1 387 ? -37.949 -21.898 -55.200  1.00 35.30  ? 380  LEU D N   1 
ATOM   13631 C CA  . LEU D 1 387 ? -36.761 -21.613 -56.043  1.00 34.60  ? 380  LEU D CA  1 
ATOM   13632 C C   . LEU D 1 387 ? -36.299 -20.170 -55.860  1.00 34.04  ? 380  LEU D C   1 
ATOM   13633 O O   . LEU D 1 387 ? -35.078 -19.944 -55.805  1.00 34.05  ? 380  LEU D O   1 
ATOM   13634 C CB  . LEU D 1 387 ? -37.161 -21.876 -57.492  1.00 36.04  ? 380  LEU D CB  1 
ATOM   13635 C CG  . LEU D 1 387 ? -37.529 -23.326 -57.795  1.00 37.94  ? 380  LEU D CG  1 
ATOM   13636 C CD1 . LEU D 1 387 ? -37.885 -23.490 -59.271  1.00 38.11  ? 380  LEU D CD1 1 
ATOM   13637 C CD2 . LEU D 1 387 ? -36.391 -24.261 -57.385  1.00 37.50  ? 380  LEU D CD2 1 
ATOM   13638 N N   . VAL D 1 388 ? -37.236 -19.230 -55.772  1.00 33.00  ? 381  VAL D N   1 
ATOM   13639 C CA  . VAL D 1 388 ? -36.922 -17.776 -55.763  1.00 32.79  ? 381  VAL D CA  1 
ATOM   13640 C C   . VAL D 1 388 ? -37.169 -17.192 -54.380  1.00 30.89  ? 381  VAL D C   1 
ATOM   13641 O O   . VAL D 1 388 ? -38.262 -17.378 -53.864  1.00 28.93  ? 381  VAL D O   1 
ATOM   13642 C CB  . VAL D 1 388 ? -37.762 -17.045 -56.813  1.00 33.15  ? 381  VAL D CB  1 
ATOM   13643 C CG1 . VAL D 1 388 ? -37.509 -15.542 -56.786  1.00 33.44  ? 381  VAL D CG1 1 
ATOM   13644 C CG2 . VAL D 1 388 ? -37.511 -17.629 -58.193  1.00 35.64  ? 381  VAL D CG2 1 
ATOM   13645 N N   . GLN D 1 389 ? -36.172 -16.497 -53.830  1.00 33.38  ? 382  GLN D N   1 
ATOM   13646 C CA  . GLN D 1 389 ? -36.308 -15.749 -52.557  1.00 35.32  ? 382  GLN D CA  1 
ATOM   13647 C C   . GLN D 1 389 ? -37.073 -14.465 -52.876  1.00 31.89  ? 382  GLN D C   1 
ATOM   13648 O O   . GLN D 1 389 ? -38.146 -14.280 -52.289  1.00 34.76  ? 382  GLN D O   1 
ATOM   13649 C CB  . GLN D 1 389 ? -34.929 -15.536 -51.918  1.00 41.15  ? 382  GLN D CB  1 
ATOM   13650 C CG  . GLN D 1 389 ? -34.870 -14.702 -50.637  1.00 46.64  ? 382  GLN D CG  1 
ATOM   13651 C CD  . GLN D 1 389 ? -35.522 -15.361 -49.457  1.00 52.14  ? 382  GLN D CD  1 
ATOM   13652 O OE1 . GLN D 1 389 ? -35.294 -16.533 -49.167  1.00 61.30  ? 382  GLN D OE1 1 
ATOM   13653 N NE2 . GLN D 1 389 ? -36.367 -14.593 -48.792  1.00 54.45  ? 382  GLN D NE2 1 
ATOM   13654 N N   . GLU D 1 390 ? -36.582 -13.653 -53.810  1.00 28.76  ? 383  GLU D N   1 
ATOM   13655 C CA  . GLU D 1 390 ? -37.204 -12.340 -54.112  1.00 27.78  ? 383  GLU D CA  1 
ATOM   13656 C C   . GLU D 1 390 ? -36.668 -11.798 -55.447  1.00 25.65  ? 383  GLU D C   1 
ATOM   13657 O O   . GLU D 1 390 ? -35.619 -12.254 -55.897  1.00 24.47  ? 383  GLU D O   1 
ATOM   13658 C CB  . GLU D 1 390 ? -37.005 -11.414 -52.901  1.00 27.54  ? 383  GLU D CB  1 
ATOM   13659 C CG  . GLU D 1 390 ? -36.228 -10.138 -53.185  1.00 30.06  ? 383  GLU D CG  1 
ATOM   13660 C CD  . GLU D 1 390 ? -36.182 -9.143  -52.041  1.00 30.42  ? 383  GLU D CD  1 
ATOM   13661 O OE1 . GLU D 1 390 ? -37.257 -8.709  -51.636  1.00 32.99  ? 383  GLU D OE1 1 
ATOM   13662 O OE2 . GLU D 1 390 ? -35.090 -8.786  -51.573  1.00 29.16  ? 383  GLU D OE2 1 
ATOM   13663 N N   . ALA D 1 391 ? -37.402 -10.878 -56.066  1.00 25.57  ? 384  ALA D N   1 
ATOM   13664 C CA  . ALA D 1 391 ? -36.965 -10.074 -57.225  1.00 26.88  ? 384  ALA D CA  1 
ATOM   13665 C C   . ALA D 1 391 ? -37.047 -8.594  -56.845  1.00 26.93  ? 384  ALA D C   1 
ATOM   13666 O O   . ALA D 1 391 ? -38.052 -8.187  -56.234  1.00 25.95  ? 384  ALA D O   1 
ATOM   13667 C CB  . ALA D 1 391 ? -37.811 -10.390 -58.439  1.00 27.88  ? 384  ALA D CB  1 
ATOM   13668 N N   . ARG D 1 392 ? -36.012 -7.831  -57.192  1.00 27.83  ? 385  ARG D N   1 
ATOM   13669 C CA  . ARG D 1 392 ? -35.872 -6.382  -56.882  1.00 27.79  ? 385  ARG D CA  1 
ATOM   13670 C C   . ARG D 1 392 ? -35.470 -5.664  -58.165  1.00 25.22  ? 385  ARG D C   1 
ATOM   13671 O O   . ARG D 1 392 ? -34.931 -6.343  -59.075  1.00 23.80  ? 385  ARG D O   1 
ATOM   13672 C CB  . ARG D 1 392 ? -34.729 -6.050  -55.906  1.00 30.37  ? 385  ARG D CB  1 
ATOM   13673 C CG  . ARG D 1 392 ? -34.347 -7.147  -54.927  1.00 31.53  ? 385  ARG D CG  1 
ATOM   13674 C CD  . ARG D 1 392 ? -33.230 -6.701  -53.985  1.00 30.31  ? 385  ARG D CD  1 
ATOM   13675 N NE  . ARG D 1 392 ? -32.000 -7.440  -54.215  1.00 29.49  ? 385  ARG D NE  1 
ATOM   13676 C CZ  . ARG D 1 392 ? -31.801 -8.712  -53.867  1.00 30.28  ? 385  ARG D CZ  1 
ATOM   13677 N NH1 . ARG D 1 392 ? -32.757 -9.406  -53.261  1.00 29.04  ? 385  ARG D NH1 1 
ATOM   13678 N NH2 . ARG D 1 392 ? -30.633 -9.285  -54.119  1.00 32.75  ? 385  ARG D NH2 1 
ATOM   13679 N N   . GLY D 1 393 ? -35.603 -4.335  -58.163  1.00 23.04  ? 386  GLY D N   1 
ATOM   13680 C CA  . GLY D 1 393 ? -35.060 -3.490  -59.239  1.00 22.29  ? 386  GLY D CA  1 
ATOM   13681 C C   . GLY D 1 393 ? -35.466 -2.039  -59.119  1.00 21.16  ? 386  GLY D C   1 
ATOM   13682 O O   . GLY D 1 393 ? -36.241 -1.690  -58.239  1.00 20.72  ? 386  GLY D O   1 
ATOM   13683 N N   . LYS D 1 394 ? -34.902 -1.231  -59.995  1.00 21.33  ? 387  LYS D N   1 
ATOM   13684 C CA  . LYS D 1 394 ? -35.288 0.164   -60.263  1.00 21.95  ? 387  LYS D CA  1 
ATOM   13685 C C   . LYS D 1 394 ? -34.955 0.421   -61.736  1.00 21.57  ? 387  LYS D C   1 
ATOM   13686 O O   . LYS D 1 394 ? -33.799 0.218   -62.139  1.00 22.32  ? 387  LYS D O   1 
ATOM   13687 C CB  . LYS D 1 394 ? -34.549 1.069   -59.284  1.00 22.48  ? 387  LYS D CB  1 
ATOM   13688 C CG  . LYS D 1 394 ? -34.626 2.560   -59.566  1.00 24.87  ? 387  LYS D CG  1 
ATOM   13689 C CD  . LYS D 1 394 ? -35.919 3.183   -59.139  1.00 28.45  ? 387  LYS D CD  1 
ATOM   13690 C CE  . LYS D 1 394 ? -35.769 4.445   -58.322  1.00 32.95  ? 387  LYS D CE  1 
ATOM   13691 N NZ  . LYS D 1 394 ? -37.105 4.851   -57.805  1.00 37.13  ? 387  LYS D NZ  1 
ATOM   13692 N N   . GLY D 1 395 ? -35.942 0.799   -62.531  1.00 20.05  ? 388  GLY D N   1 
ATOM   13693 C CA  . GLY D 1 395 ? -35.773 0.847   -63.992  1.00 20.43  ? 388  GLY D CA  1 
ATOM   13694 C C   . GLY D 1 395 ? -35.303 -0.499  -64.495  1.00 19.78  ? 388  GLY D C   1 
ATOM   13695 O O   . GLY D 1 395 ? -35.829 -1.526  -64.045  1.00 20.23  ? 388  GLY D O   1 
ATOM   13696 N N   . MET D 1 396 ? -34.300 -0.504  -65.362  1.00 22.23  ? 389  MET D N   1 
ATOM   13697 C CA  . MET D 1 396 ? -33.816 -1.726  -66.052  1.00 22.99  ? 389  MET D CA  1 
ATOM   13698 C C   . MET D 1 396 ? -32.613 -2.305  -65.306  1.00 23.14  ? 389  MET D C   1 
ATOM   13699 O O   . MET D 1 396 ? -31.883 -3.113  -65.890  1.00 22.98  ? 389  MET D O   1 
ATOM   13700 C CB  . MET D 1 396 ? -33.445 -1.401  -67.491  1.00 23.10  ? 389  MET D CB  1 
ATOM   13701 C CG  . MET D 1 396 ? -34.657 -1.065  -68.322  1.00 23.73  ? 389  MET D CG  1 
ATOM   13702 S SD  . MET D 1 396 ? -35.668 -2.536  -68.645  1.00 23.12  ? 389  MET D SD  1 
ATOM   13703 C CE  . MET D 1 396 ? -35.203 -2.925  -70.324  1.00 21.66  ? 389  MET D CE  1 
ATOM   13704 N N   . LEU D 1 397 ? -32.446 -1.913  -64.045  1.00 23.08  ? 390  LEU D N   1 
ATOM   13705 C CA  . LEU D 1 397 ? -31.475 -2.538  -63.126  1.00 22.53  ? 390  LEU D CA  1 
ATOM   13706 C C   . LEU D 1 397 ? -32.253 -3.451  -62.193  1.00 21.98  ? 390  LEU D C   1 
ATOM   13707 O O   . LEU D 1 397 ? -32.918 -2.940  -61.287  1.00 20.55  ? 390  LEU D O   1 
ATOM   13708 C CB  . LEU D 1 397 ? -30.726 -1.444  -62.371  1.00 22.39  ? 390  LEU D CB  1 
ATOM   13709 C CG  . LEU D 1 397 ? -29.588 -1.936  -61.480  1.00 23.83  ? 390  LEU D CG  1 
ATOM   13710 C CD1 . LEU D 1 397 ? -28.555 -2.766  -62.268  1.00 24.74  ? 390  LEU D CD1 1 
ATOM   13711 C CD2 . LEU D 1 397 ? -28.931 -0.734  -60.798  1.00 23.65  ? 390  LEU D CD2 1 
ATOM   13712 N N   . MET D 1 398 ? -32.174 -4.755  -62.438  1.00 22.37  ? 391  MET D N   1 
ATOM   13713 C CA  . MET D 1 398 ? -33.003 -5.762  -61.744  1.00 23.82  ? 391  MET D CA  1 
ATOM   13714 C C   . MET D 1 398 ? -32.164 -6.984  -61.393  1.00 24.85  ? 391  MET D C   1 
ATOM   13715 O O   . MET D 1 398 ? -31.117 -7.200  -62.030  1.00 25.47  ? 391  MET D O   1 
ATOM   13716 C CB  . MET D 1 398 ? -34.161 -6.203  -62.632  1.00 25.32  ? 391  MET D CB  1 
ATOM   13717 C CG  . MET D 1 398 ? -35.261 -5.168  -62.739  1.00 26.06  ? 391  MET D CG  1 
ATOM   13718 S SD  . MET D 1 398 ? -36.381 -5.526  -64.103  1.00 25.47  ? 391  MET D SD  1 
ATOM   13719 C CE  . MET D 1 398 ? -35.248 -5.371  -65.476  1.00 23.67  ? 391  MET D CE  1 
ATOM   13720 N N   . ALA D 1 399 ? -32.629 -7.728  -60.391  1.00 26.93  ? 392  ALA D N   1 
ATOM   13721 C CA  . ALA D 1 399 ? -32.026 -8.984  -59.906  1.00 25.76  ? 392  ALA D CA  1 
ATOM   13722 C C   . ALA D 1 399 ? -33.126 -9.912  -59.404  1.00 26.69  ? 392  ALA D C   1 
ATOM   13723 O O   . ALA D 1 399 ? -34.160 -9.420  -58.865  1.00 24.79  ? 392  ALA D O   1 
ATOM   13724 C CB  . ALA D 1 399 ? -31.050 -8.707  -58.801  1.00 25.91  ? 392  ALA D CB  1 
ATOM   13725 N N   . ILE D 1 400 ? -32.894 -11.208 -59.607  1.00 26.46  ? 393  ILE D N   1 
ATOM   13726 C CA  . ILE D 1 400 ? -33.651 -12.313 -58.967  1.00 28.63  ? 393  ILE D CA  1 
ATOM   13727 C C   . ILE D 1 400 ? -32.707 -13.023 -58.012  1.00 28.60  ? 393  ILE D C   1 
ATOM   13728 O O   . ILE D 1 400 ? -31.712 -13.589 -58.506  1.00 29.73  ? 393  ILE D O   1 
ATOM   13729 C CB  . ILE D 1 400 ? -34.190 -13.278 -60.032  1.00 29.89  ? 393  ILE D CB  1 
ATOM   13730 C CG1 . ILE D 1 400 ? -35.042 -12.539 -61.067  1.00 29.56  ? 393  ILE D CG1 1 
ATOM   13731 C CG2 . ILE D 1 400 ? -34.948 -14.435 -59.379  1.00 29.40  ? 393  ILE D CG2 1 
ATOM   13732 C CD1 . ILE D 1 400 ? -35.245 -13.318 -62.331  1.00 30.02  ? 393  ILE D CD1 1 
ATOM   13733 N N   . GLU D 1 401 ? -33.015 -12.984 -56.713  1.00 28.80  ? 394  GLU D N   1 
ATOM   13734 C CA  . GLU D 1 401 ? -32.313 -13.775 -55.668  1.00 29.43  ? 394  GLU D CA  1 
ATOM   13735 C C   . GLU D 1 401 ? -32.975 -15.149 -55.568  1.00 28.77  ? 394  GLU D C   1 
ATOM   13736 O O   . GLU D 1 401 ? -34.188 -15.200 -55.295  1.00 33.29  ? 394  GLU D O   1 
ATOM   13737 C CB  . GLU D 1 401 ? -32.350 -13.030 -54.339  1.00 29.51  ? 394  GLU D CB  1 
ATOM   13738 C CG  . GLU D 1 401 ? -31.499 -13.682 -53.286  1.00 33.65  ? 394  GLU D CG  1 
ATOM   13739 C CD  . GLU D 1 401 ? -31.490 -12.988 -51.940  1.00 37.41  ? 394  GLU D CD  1 
ATOM   13740 O OE1 . GLU D 1 401 ? -32.133 -11.944 -51.799  1.00 41.33  ? 394  GLU D OE1 1 
ATOM   13741 O OE2 . GLU D 1 401 ? -30.883 -13.546 -51.014  1.00 44.28  ? 394  GLU D OE2 1 
ATOM   13742 N N   . PHE D 1 402 ? -32.222 -16.222 -55.793  1.00 27.94  ? 395  PHE D N   1 
ATOM   13743 C CA  . PHE D 1 402 ? -32.716 -17.613 -55.641  1.00 29.06  ? 395  PHE D CA  1 
ATOM   13744 C C   . PHE D 1 402 ? -32.435 -18.086 -54.218  1.00 32.50  ? 395  PHE D C   1 
ATOM   13745 O O   . PHE D 1 402 ? -31.739 -17.381 -53.451  1.00 30.78  ? 395  PHE D O   1 
ATOM   13746 C CB  . PHE D 1 402 ? -32.119 -18.514 -56.716  1.00 28.48  ? 395  PHE D CB  1 
ATOM   13747 C CG  . PHE D 1 402 ? -32.548 -18.063 -58.081  1.00 29.08  ? 395  PHE D CG  1 
ATOM   13748 C CD1 . PHE D 1 402 ? -31.920 -16.992 -58.697  1.00 29.45  ? 395  PHE D CD1 1 
ATOM   13749 C CD2 . PHE D 1 402 ? -33.650 -18.632 -58.694  1.00 30.52  ? 395  PHE D CD2 1 
ATOM   13750 C CE1 . PHE D 1 402 ? -32.349 -16.530 -59.926  1.00 30.19  ? 395  PHE D CE1 1 
ATOM   13751 C CE2 . PHE D 1 402 ? -34.082 -18.172 -59.929  1.00 33.22  ? 395  PHE D CE2 1 
ATOM   13752 C CZ  . PHE D 1 402 ? -33.419 -17.130 -60.548  1.00 32.87  ? 395  PHE D CZ  1 
ATOM   13753 N N   . VAL D 1 403 ? -33.017 -19.232 -53.869  1.00 36.15  ? 396  VAL D N   1 
ATOM   13754 C CA  . VAL D 1 403 ? -32.977 -19.795 -52.495  1.00 39.22  ? 396  VAL D CA  1 
ATOM   13755 C C   . VAL D 1 403 ? -31.525 -20.147 -52.158  1.00 41.25  ? 396  VAL D C   1 
ATOM   13756 O O   . VAL D 1 403 ? -31.114 -19.861 -51.029  1.00 37.54  ? 396  VAL D O   1 
ATOM   13757 C CB  . VAL D 1 403 ? -33.931 -20.997 -52.396  1.00 39.22  ? 396  VAL D CB  1 
ATOM   13758 C CG1 . VAL D 1 403 ? -33.617 -21.895 -51.207  1.00 41.32  ? 396  VAL D CG1 1 
ATOM   13759 C CG2 . VAL D 1 403 ? -35.380 -20.531 -52.388  1.00 36.99  ? 396  VAL D CG2 1 
ATOM   13760 N N   . ASP D 1 404 ? -30.783 -20.726 -53.108  1.00 49.58  ? 397  ASP D N   1 
ATOM   13761 C CA  . ASP D 1 404 ? -29.352 -21.101 -52.933  1.00 55.19  ? 397  ASP D CA  1 
ATOM   13762 C C   . ASP D 1 404 ? -28.600 -20.887 -54.253  1.00 56.50  ? 397  ASP D C   1 
ATOM   13763 O O   . ASP D 1 404 ? -29.261 -20.673 -55.287  1.00 52.88  ? 397  ASP D O   1 
ATOM   13764 C CB  . ASP D 1 404 ? -29.220 -22.530 -52.390  1.00 61.02  ? 397  ASP D CB  1 
ATOM   13765 C CG  . ASP D 1 404 ? -29.571 -23.630 -53.379  1.00 65.03  ? 397  ASP D CG  1 
ATOM   13766 O OD1 . ASP D 1 404 ? -29.152 -23.532 -54.560  1.00 73.30  ? 397  ASP D OD1 1 
ATOM   13767 O OD2 . ASP D 1 404 ? -30.251 -24.588 -52.958  1.00 69.81  ? 397  ASP D OD2 1 
ATOM   13768 N N   . ASN D 1 405 ? -27.267 -20.963 -54.209  1.00 59.67  ? 398  ASN D N   1 
ATOM   13769 C CA  . ASN D 1 405 ? -26.378 -20.592 -55.340  1.00 57.65  ? 398  ASN D CA  1 
ATOM   13770 C C   . ASN D 1 405 ? -26.632 -21.526 -56.523  1.00 50.41  ? 398  ASN D C   1 
ATOM   13771 O O   . ASN D 1 405 ? -26.747 -21.004 -57.642  1.00 44.80  ? 398  ASN D O   1 
ATOM   13772 C CB  . ASN D 1 405 ? -24.896 -20.573 -54.956  1.00 65.74  ? 398  ASN D CB  1 
ATOM   13773 C CG  . ASN D 1 405 ? -24.115 -19.516 -55.714  1.00 81.08  ? 398  ASN D CG  1 
ATOM   13774 O OD1 . ASN D 1 405 ? -24.627 -18.850 -56.617  1.00 96.16  ? 398  ASN D OD1 1 
ATOM   13775 N ND2 . ASN D 1 405 ? -22.857 -19.344 -55.347  1.00 92.49  ? 398  ASN D ND2 1 
ATOM   13776 N N   . GLU D 1 406 ? -26.730 -22.834 -56.282  1.00 46.67  ? 399  GLU D N   1 
ATOM   13777 C CA  . GLU D 1 406 ? -26.818 -23.866 -57.347  1.00 48.45  ? 399  GLU D CA  1 
ATOM   13778 C C   . GLU D 1 406 ? -28.111 -23.694 -58.143  1.00 47.92  ? 399  GLU D C   1 
ATOM   13779 O O   . GLU D 1 406 ? -28.087 -23.988 -59.351  1.00 54.85  ? 399  GLU D O   1 
ATOM   13780 C CB  . GLU D 1 406 ? -26.762 -25.284 -56.786  1.00 56.37  ? 399  GLU D CB  1 
ATOM   13781 C CG  . GLU D 1 406 ? -26.668 -26.324 -57.895  1.00 67.40  ? 399  GLU D CG  1 
ATOM   13782 C CD  . GLU D 1 406 ? -27.288 -27.673 -57.571  1.00 82.14  ? 399  GLU D CD  1 
ATOM   13783 O OE1 . GLU D 1 406 ? -27.166 -28.113 -56.396  1.00 83.62  ? 399  GLU D OE1 1 
ATOM   13784 O OE2 . GLU D 1 406 ? -27.903 -28.278 -58.491  1.00 88.72  ? 399  GLU D OE2 1 
ATOM   13785 N N   . ILE D 1 407 ? -29.188 -23.236 -57.501  1.00 41.93  ? 400  ILE D N   1 
ATOM   13786 C CA  . ILE D 1 407 ? -30.495 -22.927 -58.158  1.00 38.99  ? 400  ILE D CA  1 
ATOM   13787 C C   . ILE D 1 407 ? -30.316 -21.731 -59.109  1.00 37.03  ? 400  ILE D C   1 
ATOM   13788 O O   . ILE D 1 407 ? -30.801 -21.827 -60.243  1.00 33.11  ? 400  ILE D O   1 
ATOM   13789 C CB  . ILE D 1 407 ? -31.597 -22.686 -57.097  1.00 38.00  ? 400  ILE D CB  1 
ATOM   13790 C CG1 . ILE D 1 407 ? -31.975 -23.974 -56.358  1.00 34.81  ? 400  ILE D CG1 1 
ATOM   13791 C CG2 . ILE D 1 407 ? -32.813 -22.025 -57.724  1.00 38.08  ? 400  ILE D CG2 1 
ATOM   13792 C CD1 . ILE D 1 407 ? -32.812 -23.760 -55.129  1.00 35.02  ? 400  ILE D CD1 1 
ATOM   13793 N N   . GLY D 1 408 ? -29.640 -20.661 -58.666  1.00 36.99  ? 401  GLY D N   1 
ATOM   13794 C CA  . GLY D 1 408 ? -29.277 -19.481 -59.485  1.00 38.42  ? 401  GLY D CA  1 
ATOM   13795 C C   . GLY D 1 408 ? -28.565 -19.883 -60.766  1.00 39.37  ? 401  GLY D C   1 
ATOM   13796 O O   . GLY D 1 408 ? -28.894 -19.348 -61.831  1.00 36.01  ? 401  GLY D O   1 
ATOM   13797 N N   . TYR D 1 409 ? -27.642 -20.836 -60.671  1.00 44.30  ? 402  TYR D N   1 
ATOM   13798 C CA  . TYR D 1 409 ? -26.836 -21.352 -61.805  1.00 47.35  ? 402  TYR D CA  1 
ATOM   13799 C C   . TYR D 1 409 ? -27.753 -22.165 -62.711  1.00 44.53  ? 402  TYR D C   1 
ATOM   13800 O O   . TYR D 1 409 ? -27.597 -22.071 -63.924  1.00 43.63  ? 402  TYR D O   1 
ATOM   13801 C CB  . TYR D 1 409 ? -25.650 -22.208 -61.343  1.00 57.10  ? 402  TYR D CB  1 
ATOM   13802 C CG  . TYR D 1 409 ? -24.689 -21.559 -60.372  1.00 68.68  ? 402  TYR D CG  1 
ATOM   13803 C CD1 . TYR D 1 409 ? -24.412 -20.198 -60.424  1.00 77.37  ? 402  TYR D CD1 1 
ATOM   13804 C CD2 . TYR D 1 409 ? -24.030 -22.316 -59.411  1.00 71.56  ? 402  TYR D CD2 1 
ATOM   13805 C CE1 . TYR D 1 409 ? -23.526 -19.604 -59.537  1.00 81.71  ? 402  TYR D CE1 1 
ATOM   13806 C CE2 . TYR D 1 409 ? -23.145 -21.736 -58.513  1.00 75.40  ? 402  TYR D CE2 1 
ATOM   13807 C CZ  . TYR D 1 409 ? -22.885 -20.376 -58.581  1.00 81.00  ? 402  TYR D CZ  1 
ATOM   13808 O OH  . TYR D 1 409 ? -22.004 -19.781 -57.724  1.00 78.19  ? 402  TYR D OH  1 
ATOM   13809 N N   . ASN D 1 410 ? -28.677 -22.940 -62.149  1.00 41.84  ? 403  ASN D N   1 
ATOM   13810 C CA  . ASN D 1 410 ? -29.617 -23.767 -62.949  1.00 43.94  ? 403  ASN D CA  1 
ATOM   13811 C C   . ASN D 1 410 ? -30.514 -22.858 -63.777  1.00 39.50  ? 403  ASN D C   1 
ATOM   13812 O O   . ASN D 1 410 ? -30.826 -23.241 -64.922  1.00 39.84  ? 403  ASN D O   1 
ATOM   13813 C CB  . ASN D 1 410 ? -30.433 -24.713 -62.074  1.00 47.49  ? 403  ASN D CB  1 
ATOM   13814 C CG  . ASN D 1 410 ? -29.576 -25.856 -61.585  1.00 55.23  ? 403  ASN D CG  1 
ATOM   13815 O OD1 . ASN D 1 410 ? -28.731 -26.362 -62.323  1.00 67.82  ? 403  ASN D OD1 1 
ATOM   13816 N ND2 . ASN D 1 410 ? -29.743 -26.232 -60.332  1.00 61.82  ? 403  ASN D ND2 1 
ATOM   13817 N N   . PHE D 1 411 ? -30.874 -21.696 -63.229  1.00 33.95  ? 404  PHE D N   1 
ATOM   13818 C CA  . PHE D 1 411 ? -31.726 -20.687 -63.901  1.00 32.26  ? 404  PHE D CA  1 
ATOM   13819 C C   . PHE D 1 411 ? -30.965 -20.061 -65.069  1.00 30.04  ? 404  PHE D C   1 
ATOM   13820 O O   . PHE D 1 411 ? -31.498 -20.023 -66.164  1.00 30.15  ? 404  PHE D O   1 
ATOM   13821 C CB  . PHE D 1 411 ? -32.153 -19.605 -62.917  1.00 29.76  ? 404  PHE D CB  1 
ATOM   13822 C CG  . PHE D 1 411 ? -33.023 -18.542 -63.524  1.00 29.40  ? 404  PHE D CG  1 
ATOM   13823 C CD1 . PHE D 1 411 ? -34.378 -18.771 -63.724  1.00 29.51  ? 404  PHE D CD1 1 
ATOM   13824 C CD2 . PHE D 1 411 ? -32.488 -17.312 -63.879  1.00 28.33  ? 404  PHE D CD2 1 
ATOM   13825 C CE1 . PHE D 1 411 ? -35.182 -17.788 -64.271  1.00 29.53  ? 404  PHE D CE1 1 
ATOM   13826 C CE2 . PHE D 1 411 ? -33.295 -16.329 -64.418  1.00 28.13  ? 404  PHE D CE2 1 
ATOM   13827 C CZ  . PHE D 1 411 ? -34.639 -16.567 -64.608  1.00 29.18  ? 404  PHE D CZ  1 
ATOM   13828 N N   . ALA D 1 412 ? -29.751 -19.573 -64.824  1.00 30.59  ? 405  ALA D N   1 
ATOM   13829 C CA  . ALA D 1 412 ? -28.871 -19.007 -65.873  1.00 28.48  ? 405  ALA D CA  1 
ATOM   13830 C C   . ALA D 1 412 ? -28.781 -19.992 -67.039  1.00 28.48  ? 405  ALA D C   1 
ATOM   13831 O O   . ALA D 1 412 ? -28.898 -19.517 -68.175  1.00 28.93  ? 405  ALA D O   1 
ATOM   13832 C CB  . ALA D 1 412 ? -27.511 -18.681 -65.306  1.00 28.41  ? 405  ALA D CB  1 
ATOM   13833 N N   . SER D 1 413 ? -28.611 -21.300 -66.767  1.00 30.69  ? 406  SER D N   1 
ATOM   13834 C CA  . SER D 1 413 ? -28.442 -22.380 -67.787  1.00 32.74  ? 406  SER D CA  1 
ATOM   13835 C C   . SER D 1 413 ? -29.744 -22.560 -68.541  1.00 32.86  ? 406  SER D C   1 
ATOM   13836 O O   . SER D 1 413 ? -29.683 -22.598 -69.763  1.00 36.29  ? 406  SER D O   1 
ATOM   13837 C CB  . SER D 1 413 ? -28.057 -23.709 -67.222  1.00 33.67  ? 406  SER D CB  1 
ATOM   13838 O OG  . SER D 1 413 ? -27.127 -23.542 -66.176  1.00 44.66  ? 406  SER D OG  1 
ATOM   13839 N N   . GLU D 1 414 ? -30.853 -22.713 -67.817  1.00 32.18  ? 407  GLU D N   1 
ATOM   13840 C CA  . GLU D 1 414 ? -32.198 -22.907 -68.408  1.00 34.31  ? 407  GLU D CA  1 
ATOM   13841 C C   . GLU D 1 414 ? -32.496 -21.733 -69.343  1.00 32.65  ? 407  GLU D C   1 
ATOM   13842 O O   . GLU D 1 414 ? -32.914 -22.003 -70.481  1.00 35.33  ? 407  GLU D O   1 
ATOM   13843 C CB  . GLU D 1 414 ? -33.248 -23.076 -67.308  1.00 39.80  ? 407  GLU D CB  1 
ATOM   13844 C CG  . GLU D 1 414 ? -33.400 -24.513 -66.857  1.00 45.18  ? 407  GLU D CG  1 
ATOM   13845 C CD  . GLU D 1 414 ? -33.703 -25.478 -67.996  1.00 54.33  ? 407  GLU D CD  1 
ATOM   13846 O OE1 . GLU D 1 414 ? -34.446 -25.117 -68.948  1.00 57.80  ? 407  GLU D OE1 1 
ATOM   13847 O OE2 . GLU D 1 414 ? -33.196 -26.601 -67.930  1.00 66.54  ? 407  GLU D OE2 1 
ATOM   13848 N N   . MET D 1 415 ? -32.242 -20.498 -68.900  1.00 30.43  ? 408  MET D N   1 
ATOM   13849 C CA  . MET D 1 415 ? -32.443 -19.269 -69.718  1.00 30.47  ? 408  MET D CA  1 
ATOM   13850 C C   . MET D 1 415 ? -31.576 -19.312 -70.980  1.00 30.84  ? 408  MET D C   1 
ATOM   13851 O O   . MET D 1 415 ? -32.070 -18.987 -72.067  1.00 31.60  ? 408  MET D O   1 
ATOM   13852 C CB  . MET D 1 415 ? -32.104 -18.016 -68.910  1.00 29.50  ? 408  MET D CB  1 
ATOM   13853 C CG  . MET D 1 415 ? -33.144 -17.732 -67.861  1.00 29.82  ? 408  MET D CG  1 
ATOM   13854 S SD  . MET D 1 415 ? -34.774 -17.377 -68.548  1.00 29.78  ? 408  MET D SD  1 
ATOM   13855 C CE  . MET D 1 415 ? -34.693 -15.587 -68.642  1.00 29.55  ? 408  MET D CE  1 
ATOM   13856 N N   . PHE D 1 416 ? -30.317 -19.700 -70.841  1.00 32.68  ? 409  PHE D N   1 
ATOM   13857 C CA  . PHE D 1 416 ? -29.359 -19.816 -71.964  1.00 33.40  ? 409  PHE D CA  1 
ATOM   13858 C C   . PHE D 1 416 ? -29.852 -20.892 -72.935  1.00 36.28  ? 409  PHE D C   1 
ATOM   13859 O O   . PHE D 1 416 ? -29.753 -20.678 -74.155  1.00 38.43  ? 409  PHE D O   1 
ATOM   13860 C CB  . PHE D 1 416 ? -27.967 -20.125 -71.411  1.00 33.90  ? 409  PHE D CB  1 
ATOM   13861 C CG  . PHE D 1 416 ? -26.853 -19.989 -72.401  1.00 32.83  ? 409  PHE D CG  1 
ATOM   13862 C CD1 . PHE D 1 416 ? -26.227 -18.771 -72.581  1.00 34.22  ? 409  PHE D CD1 1 
ATOM   13863 C CD2 . PHE D 1 416 ? -26.443 -21.081 -73.143  1.00 33.71  ? 409  PHE D CD2 1 
ATOM   13864 C CE1 . PHE D 1 416 ? -25.203 -18.647 -73.501  1.00 35.38  ? 409  PHE D CE1 1 
ATOM   13865 C CE2 . PHE D 1 416 ? -25.426 -20.951 -74.069  1.00 36.24  ? 409  PHE D CE2 1 
ATOM   13866 C CZ  . PHE D 1 416 ? -24.810 -19.734 -74.246  1.00 36.28  ? 409  PHE D CZ  1 
ATOM   13867 N N   . ARG D 1 417 ? -30.386 -22.000 -72.416  1.00 42.23  ? 410  ARG D N   1 
ATOM   13868 C CA  . ARG D 1 417 ? -30.933 -23.101 -73.255  1.00 53.35  ? 410  ARG D CA  1 
ATOM   13869 C C   . ARG D 1 417 ? -32.033 -22.516 -74.142  1.00 47.33  ? 410  ARG D C   1 
ATOM   13870 O O   . ARG D 1 417 ? -32.161 -22.963 -75.292  1.00 45.94  ? 410  ARG D O   1 
ATOM   13871 C CB  . ARG D 1 417 ? -31.414 -24.299 -72.425  1.00 61.93  ? 410  ARG D CB  1 
ATOM   13872 C CG  . ARG D 1 417 ? -30.629 -25.560 -72.781  1.00 75.57  ? 410  ARG D CG  1 
ATOM   13873 C CD  . ARG D 1 417 ? -30.983 -26.851 -72.061  1.00 87.35  ? 410  ARG D CD  1 
ATOM   13874 N NE  . ARG D 1 417 ? -31.050 -26.774 -70.607  1.00 100.98 ? 410  ARG D NE  1 
ATOM   13875 C CZ  . ARG D 1 417 ? -30.049 -26.449 -69.770  1.00 117.28 ? 410  ARG D CZ  1 
ATOM   13876 N NH1 . ARG D 1 417 ? -28.844 -26.128 -70.215  1.00 126.62 ? 410  ARG D NH1 1 
ATOM   13877 N NH2 . ARG D 1 417 ? -30.259 -26.428 -68.465  1.00 114.64 ? 410  ARG D NH2 1 
ATOM   13878 N N   . GLN D 1 418 ? -32.741 -21.510 -73.633  1.00 42.23  ? 411  GLN D N   1 
ATOM   13879 C CA  . GLN D 1 418 ? -33.879 -20.871 -74.328  1.00 44.52  ? 411  GLN D CA  1 
ATOM   13880 C C   . GLN D 1 418 ? -33.446 -19.572 -75.000  1.00 43.68  ? 411  GLN D C   1 
ATOM   13881 O O   . GLN D 1 418 ? -34.342 -18.770 -75.367  1.00 47.01  ? 411  GLN D O   1 
ATOM   13882 C CB  . GLN D 1 418 ? -34.986 -20.639 -73.318  1.00 46.57  ? 411  GLN D CB  1 
ATOM   13883 C CG  . GLN D 1 418 ? -35.511 -21.943 -72.740  1.00 49.14  ? 411  GLN D CG  1 
ATOM   13884 C CD  . GLN D 1 418 ? -36.570 -21.621 -71.735  1.00 50.97  ? 411  GLN D CD  1 
ATOM   13885 O OE1 . GLN D 1 418 ? -37.635 -21.127 -72.099  1.00 53.23  ? 411  GLN D OE1 1 
ATOM   13886 N NE2 . GLN D 1 418 ? -36.241 -21.825 -70.469  1.00 54.56  ? 411  GLN D NE2 1 
ATOM   13887 N N   . ARG D 1 419 ? -32.138 -19.379 -75.175  1.00 40.01  ? 412  ARG D N   1 
ATOM   13888 C CA  . ARG D 1 419 ? -31.570 -18.264 -75.975  1.00 41.67  ? 412  ARG D CA  1 
ATOM   13889 C C   . ARG D 1 419 ? -31.945 -16.923 -75.328  1.00 34.65  ? 412  ARG D C   1 
ATOM   13890 O O   . ARG D 1 419 ? -32.220 -15.963 -76.064  1.00 30.89  ? 412  ARG D O   1 
ATOM   13891 C CB  . ARG D 1 419 ? -32.012 -18.368 -77.445  1.00 47.56  ? 412  ARG D CB  1 
ATOM   13892 C CG  . ARG D 1 419 ? -31.549 -19.626 -78.179  1.00 52.38  ? 412  ARG D CG  1 
ATOM   13893 C CD  . ARG D 1 419 ? -30.269 -20.202 -77.606  1.00 56.09  ? 412  ARG D CD  1 
ATOM   13894 N NE  . ARG D 1 419 ? -29.881 -21.485 -78.182  1.00 60.42  ? 412  ARG D NE  1 
ATOM   13895 C CZ  . ARG D 1 419 ? -29.047 -22.353 -77.596  1.00 66.59  ? 412  ARG D CZ  1 
ATOM   13896 N NH1 . ARG D 1 419 ? -28.555 -22.098 -76.389  1.00 70.63  ? 412  ARG D NH1 1 
ATOM   13897 N NH2 . ARG D 1 419 ? -28.724 -23.481 -78.204  1.00 67.47  ? 412  ARG D NH2 1 
ATOM   13898 N N   . VAL D 1 420 ? -31.908 -16.857 -73.996  1.00 31.70  ? 413  VAL D N   1 
ATOM   13899 C CA  . VAL D 1 420 ? -31.957 -15.577 -73.240  1.00 32.46  ? 413  VAL D CA  1 
ATOM   13900 C C   . VAL D 1 420 ? -30.727 -15.499 -72.345  1.00 34.08  ? 413  VAL D C   1 
ATOM   13901 O O   . VAL D 1 420 ? -30.490 -16.426 -71.550  1.00 34.55  ? 413  VAL D O   1 
ATOM   13902 C CB  . VAL D 1 420 ? -33.242 -15.416 -72.420  1.00 34.36  ? 413  VAL D CB  1 
ATOM   13903 C CG1 . VAL D 1 420 ? -33.243 -14.101 -71.658  1.00 34.46  ? 413  VAL D CG1 1 
ATOM   13904 C CG2 . VAL D 1 420 ? -34.474 -15.523 -73.301  1.00 33.27  ? 413  VAL D CG2 1 
ATOM   13905 N N   . LEU D 1 421 ? -30.003 -14.395 -72.479  1.00 35.11  ? 414  LEU D N   1 
ATOM   13906 C CA  . LEU D 1 421 ? -28.675 -14.188 -71.876  1.00 35.47  ? 414  LEU D CA  1 
ATOM   13907 C C   . LEU D 1 421 ? -28.843 -13.408 -70.573  1.00 33.03  ? 414  LEU D C   1 
ATOM   13908 O O   . LEU D 1 421 ? -29.243 -12.242 -70.619  1.00 32.05  ? 414  LEU D O   1 
ATOM   13909 C CB  . LEU D 1 421 ? -27.812 -13.433 -72.889  1.00 38.54  ? 414  LEU D CB  1 
ATOM   13910 C CG  . LEU D 1 421 ? -26.330 -13.334 -72.535  1.00 42.88  ? 414  LEU D CG  1 
ATOM   13911 C CD1 . LEU D 1 421 ? -25.747 -14.705 -72.208  1.00 46.32  ? 414  LEU D CD1 1 
ATOM   13912 C CD2 . LEU D 1 421 ? -25.555 -12.673 -73.655  1.00 42.42  ? 414  LEU D CD2 1 
ATOM   13913 N N   . VAL D 1 422 ? -28.554 -14.067 -69.455  1.00 33.46  ? 415  VAL D N   1 
ATOM   13914 C CA  . VAL D 1 422 ? -28.424 -13.469 -68.096  1.00 34.41  ? 415  VAL D CA  1 
ATOM   13915 C C   . VAL D 1 422 ? -27.100 -13.967 -67.500  1.00 36.82  ? 415  VAL D C   1 
ATOM   13916 O O   . VAL D 1 422 ? -26.504 -14.894 -68.084  1.00 33.60  ? 415  VAL D O   1 
ATOM   13917 C CB  . VAL D 1 422 ? -29.615 -13.896 -67.231  1.00 33.96  ? 415  VAL D CB  1 
ATOM   13918 C CG1 . VAL D 1 422 ? -30.920 -13.392 -67.816  1.00 36.35  ? 415  VAL D CG1 1 
ATOM   13919 C CG2 . VAL D 1 422 ? -29.651 -15.409 -67.044  1.00 33.63  ? 415  VAL D CG2 1 
ATOM   13920 N N   . ALA D 1 423 ? -26.677 -13.438 -66.356  1.00 36.80  ? 416  ALA D N   1 
ATOM   13921 C CA  . ALA D 1 423 ? -25.519 -13.993 -65.626  1.00 40.93  ? 416  ALA D CA  1 
ATOM   13922 C C   . ALA D 1 423 ? -25.585 -13.532 -64.187  1.00 40.04  ? 416  ALA D C   1 
ATOM   13923 O O   . ALA D 1 423 ? -26.415 -12.685 -63.909  1.00 42.62  ? 416  ALA D O   1 
ATOM   13924 C CB  . ALA D 1 423 ? -24.225 -13.556 -66.270  1.00 40.95  ? 416  ALA D CB  1 
ATOM   13925 N N   . GLY D 1 424 ? -24.694 -14.061 -63.349  1.00 47.78  ? 417  GLY D N   1 
ATOM   13926 C CA  . GLY D 1 424 ? -24.581 -13.730 -61.915  1.00 48.07  ? 417  GLY D CA  1 
ATOM   13927 C C   . GLY D 1 424 ? -24.008 -12.341 -61.660  1.00 50.48  ? 417  GLY D C   1 
ATOM   13928 O O   . GLY D 1 424 ? -23.410 -11.731 -62.588  1.00 50.54  ? 417  GLY D O   1 
ATOM   13929 N N   . THR D 1 425 ? -24.198 -11.856 -60.425  1.00 57.46  ? 418  THR D N   1 
ATOM   13930 C CA  . THR D 1 425 ? -23.587 -10.622 -59.848  1.00 58.57  ? 418  THR D CA  1 
ATOM   13931 C C   . THR D 1 425 ? -22.247 -10.986 -59.172  1.00 56.65  ? 418  THR D C   1 
ATOM   13932 O O   . THR D 1 425 ? -22.049 -12.185 -58.834  1.00 51.37  ? 418  THR D O   1 
ATOM   13933 C CB  . THR D 1 425 ? -24.562 -9.911  -58.892  1.00 53.31  ? 418  THR D CB  1 
ATOM   13934 O OG1 . THR D 1 425 ? -25.052 -10.860 -57.946  1.00 51.50  ? 418  THR D OG1 1 
ATOM   13935 C CG2 . THR D 1 425 ? -25.736 -9.266  -59.603  1.00 54.85  ? 418  THR D CG2 1 
ATOM   13936 N N   . LEU D 1 426 ? -21.358 -9.997  -59.000  1.00 59.04  ? 419  LEU D N   1 
ATOM   13937 C CA  . LEU D 1 426 ? -20.002 -10.178 -58.410  1.00 62.51  ? 419  LEU D CA  1 
ATOM   13938 C C   . LEU D 1 426 ? -20.120 -10.280 -56.873  1.00 66.57  ? 419  LEU D C   1 
ATOM   13939 O O   . LEU D 1 426 ? -19.913 -11.397 -56.352  1.00 73.70  ? 419  LEU D O   1 
ATOM   13940 C CB  . LEU D 1 426 ? -19.071 -9.048  -58.882  1.00 62.98  ? 419  LEU D CB  1 
ATOM   13941 C CG  . LEU D 1 426 ? -18.496 -9.172  -60.306  1.00 63.07  ? 419  LEU D CG  1 
ATOM   13942 C CD1 . LEU D 1 426 ? -17.709 -7.922  -60.699  1.00 61.99  ? 419  LEU D CD1 1 
ATOM   13943 C CD2 . LEU D 1 426 ? -17.606 -10.401 -60.463  1.00 58.88  ? 419  LEU D CD2 1 
ATOM   13944 N N   . ASN D 1 427 ? -20.512 -9.214  -56.164  1.00 68.75  ? 420  ASN D N   1 
ATOM   13945 C CA  . ASN D 1 427 ? -20.504 -9.169  -54.667  1.00 70.76  ? 420  ASN D CA  1 
ATOM   13946 C C   . ASN D 1 427 ? -21.781 -9.804  -54.099  1.00 71.44  ? 420  ASN D C   1 
ATOM   13947 O O   . ASN D 1 427 ? -22.276 -9.297  -53.067  1.00 74.85  ? 420  ASN D O   1 
ATOM   13948 C CB  . ASN D 1 427 ? -20.333 -7.742  -54.126  1.00 71.23  ? 420  ASN D CB  1 
ATOM   13949 C CG  . ASN D 1 427 ? -19.128 -7.036  -54.710  1.00 73.99  ? 420  ASN D CG  1 
ATOM   13950 O OD1 . ASN D 1 427 ? -18.569 -7.503  -55.701  1.00 86.40  ? 420  ASN D OD1 1 
ATOM   13951 N ND2 . ASN D 1 427 ? -18.716 -5.926  -54.110  1.00 65.42  ? 420  ASN D ND2 1 
ATOM   13952 N N   . ASN D 1 428 ? -22.289 -10.871 -54.729  1.00 70.28  ? 421  ASN D N   1 
ATOM   13953 C CA  . ASN D 1 428 ? -23.564 -11.546 -54.355  1.00 69.15  ? 421  ASN D CA  1 
ATOM   13954 C C   . ASN D 1 428 ? -23.738 -12.828 -55.186  1.00 71.62  ? 421  ASN D C   1 
ATOM   13955 O O   . ASN D 1 428 ? -24.043 -12.727 -56.393  1.00 83.96  ? 421  ASN D O   1 
ATOM   13956 C CB  . ASN D 1 428 ? -24.778 -10.619 -54.520  1.00 66.35  ? 421  ASN D CB  1 
ATOM   13957 C CG  . ASN D 1 428 ? -26.023 -11.108 -53.798  1.00 66.10  ? 421  ASN D CG  1 
ATOM   13958 O OD1 . ASN D 1 428 ? -26.122 -12.272 -53.402  1.00 56.81  ? 421  ASN D OD1 1 
ATOM   13959 N ND2 . ASN D 1 428 ? -26.990 -10.222 -53.611  1.00 69.45  ? 421  ASN D ND2 1 
ATOM   13960 N N   . ALA D 1 429 ? -23.574 -13.993 -54.553  1.00 68.69  ? 422  ALA D N   1 
ATOM   13961 C CA  . ALA D 1 429 ? -23.834 -15.332 -55.138  1.00 65.65  ? 422  ALA D CA  1 
ATOM   13962 C C   . ALA D 1 429 ? -25.352 -15.552 -55.257  1.00 69.96  ? 422  ALA D C   1 
ATOM   13963 O O   . ALA D 1 429 ? -26.108 -14.764 -54.635  1.00 79.04  ? 422  ALA D O   1 
ATOM   13964 C CB  . ALA D 1 429 ? -23.183 -16.379 -54.267  1.00 62.92  ? 422  ALA D CB  1 
ATOM   13965 N N   . LYS D 1 430 ? -25.801 -16.555 -56.033  1.00 66.49  ? 423  LYS D N   1 
ATOM   13966 C CA  . LYS D 1 430 ? -27.226 -17.026 -56.088  1.00 52.21  ? 423  LYS D CA  1 
ATOM   13967 C C   . LYS D 1 430 ? -28.189 -15.922 -56.544  1.00 44.59  ? 423  LYS D C   1 
ATOM   13968 O O   . LYS D 1 430 ? -29.420 -16.130 -56.444  1.00 48.20  ? 423  LYS D O   1 
ATOM   13969 C CB  . LYS D 1 430 ? -27.679 -17.568 -54.729  1.00 49.64  ? 423  LYS D CB  1 
ATOM   13970 C CG  . LYS D 1 430 ? -28.115 -16.600 -53.645  1.00 49.55  ? 423  LYS D CG  1 
ATOM   13971 C CD  . LYS D 1 430 ? -28.237 -17.334 -52.321  1.00 49.40  ? 423  LYS D CD  1 
ATOM   13972 C CE  . LYS D 1 430 ? -27.959 -16.462 -51.111  1.00 57.20  ? 423  LYS D CE  1 
ATOM   13973 N NZ  . LYS D 1 430 ? -29.037 -15.464 -50.897  1.00 61.23  ? 423  LYS D NZ  1 
ATOM   13974 N N   . THR D 1 431 ? -27.652 -14.810 -57.052  1.00 36.37  ? 424  THR D N   1 
ATOM   13975 C CA  . THR D 1 431 ? -28.397 -13.615 -57.529  1.00 33.58  ? 424  THR D CA  1 
ATOM   13976 C C   . THR D 1 431 ? -28.084 -13.417 -59.010  1.00 29.52  ? 424  THR D C   1 
ATOM   13977 O O   . THR D 1 431 ? -26.895 -13.341 -59.363  1.00 29.76  ? 424  THR D O   1 
ATOM   13978 C CB  . THR D 1 431 ? -28.099 -12.387 -56.656  1.00 33.51  ? 424  THR D CB  1 
ATOM   13979 O OG1 . THR D 1 431 ? -28.539 -12.755 -55.350  1.00 34.25  ? 424  THR D OG1 1 
ATOM   13980 C CG2 . THR D 1 431 ? -28.810 -11.118 -57.074  1.00 34.81  ? 424  THR D CG2 1 
ATOM   13981 N N   . ILE D 1 432 ? -29.124 -13.382 -59.843  1.00 26.32  ? 425  ILE D N   1 
ATOM   13982 C CA  . ILE D 1 432 ? -29.008 -13.216 -61.316  1.00 24.57  ? 425  ILE D CA  1 
ATOM   13983 C C   . ILE D 1 432 ? -29.432 -11.796 -61.661  1.00 23.61  ? 425  ILE D C   1 
ATOM   13984 O O   . ILE D 1 432 ? -30.529 -11.416 -61.288  1.00 21.75  ? 425  ILE D O   1 
ATOM   13985 C CB  . ILE D 1 432 ? -29.851 -14.286 -62.014  1.00 25.33  ? 425  ILE D CB  1 
ATOM   13986 C CG1 . ILE D 1 432 ? -29.365 -15.690 -61.648  1.00 24.90  ? 425  ILE D CG1 1 
ATOM   13987 C CG2 . ILE D 1 432 ? -29.877 -14.067 -63.522  1.00 27.22  ? 425  ILE D CG2 1 
ATOM   13988 C CD1 . ILE D 1 432 ? -28.072 -16.073 -62.304  1.00 23.82  ? 425  ILE D CD1 1 
ATOM   13989 N N   . ARG D 1 433 ? -28.552 -11.035 -62.305  1.00 27.28  ? 426  ARG D N   1 
ATOM   13990 C CA  . ARG D 1 433 ? -28.837 -9.655  -62.783  1.00 31.79  ? 426  ARG D CA  1 
ATOM   13991 C C   . ARG D 1 433 ? -29.682 -9.744  -64.055  1.00 30.55  ? 426  ARG D C   1 
ATOM   13992 O O   . ARG D 1 433 ? -29.422 -10.623 -64.910  1.00 35.16  ? 426  ARG D O   1 
ATOM   13993 C CB  . ARG D 1 433 ? -27.550 -8.863  -63.042  1.00 38.21  ? 426  ARG D CB  1 
ATOM   13994 C CG  . ARG D 1 433 ? -26.738 -9.325  -64.255  1.00 44.69  ? 426  ARG D CG  1 
ATOM   13995 C CD  . ARG D 1 433 ? -25.365 -8.679  -64.405  1.00 48.27  ? 426  ARG D CD  1 
ATOM   13996 N NE  . ARG D 1 433 ? -24.743 -8.438  -63.101  1.00 54.77  ? 426  ARG D NE  1 
ATOM   13997 C CZ  . ARG D 1 433 ? -24.105 -7.325  -62.733  1.00 58.91  ? 426  ARG D CZ  1 
ATOM   13998 N NH1 . ARG D 1 433 ? -23.950 -6.307  -63.567  1.00 60.68  ? 426  ARG D NH1 1 
ATOM   13999 N NH2 . ARG D 1 433 ? -23.625 -7.232  -61.507  1.00 62.67  ? 426  ARG D NH2 1 
ATOM   14000 N N   . ILE D 1 434 ? -30.683 -8.883  -64.160  1.00 26.17  ? 427  ILE D N   1 
ATOM   14001 C CA  . ILE D 1 434 ? -31.409 -8.636  -65.426  1.00 25.68  ? 427  ILE D CA  1 
ATOM   14002 C C   . ILE D 1 434 ? -31.145 -7.182  -65.779  1.00 25.33  ? 427  ILE D C   1 
ATOM   14003 O O   . ILE D 1 434 ? -31.680 -6.292  -65.095  1.00 25.00  ? 427  ILE D O   1 
ATOM   14004 C CB  . ILE D 1 434 ? -32.900 -8.951  -65.277  1.00 26.72  ? 427  ILE D CB  1 
ATOM   14005 C CG1 . ILE D 1 434 ? -33.124 -10.347 -64.688  1.00 28.37  ? 427  ILE D CG1 1 
ATOM   14006 C CG2 . ILE D 1 434 ? -33.608 -8.771  -66.598  1.00 25.35  ? 427  ILE D CG2 1 
ATOM   14007 C CD1 . ILE D 1 434 ? -32.788 -11.472 -65.631  1.00 29.65  ? 427  ILE D CD1 1 
ATOM   14008 N N   . GLU D 1 435 ? -30.295 -6.977  -66.782  1.00 25.02  ? 428  GLU D N   1 
ATOM   14009 C CA  . GLU D 1 435 ? -29.794 -5.648  -67.212  1.00 24.60  ? 428  GLU D CA  1 
ATOM   14010 C C   . GLU D 1 435 ? -29.893 -5.559  -68.732  1.00 23.18  ? 428  GLU D C   1 
ATOM   14011 O O   . GLU D 1 435 ? -28.879 -5.451  -69.415  1.00 21.81  ? 428  GLU D O   1 
ATOM   14012 C CB  . GLU D 1 435 ? -28.348 -5.468  -66.752  1.00 24.54  ? 428  GLU D CB  1 
ATOM   14013 C CG  . GLU D 1 435 ? -28.217 -4.766  -65.413  1.00 25.93  ? 428  GLU D CG  1 
ATOM   14014 C CD  . GLU D 1 435 ? -26.783 -4.421  -65.035  1.00 25.99  ? 428  GLU D CD  1 
ATOM   14015 O OE1 . GLU D 1 435 ? -26.277 -3.388  -65.507  1.00 25.82  ? 428  GLU D OE1 1 
ATOM   14016 O OE2 . GLU D 1 435 ? -26.167 -5.209  -64.296  1.00 26.67  ? 428  GLU D OE2 1 
ATOM   14017 N N   . PRO D 1 436 ? -31.107 -5.606  -69.312  1.00 21.32  ? 429  PRO D N   1 
ATOM   14018 C CA  . PRO D 1 436 ? -31.248 -5.587  -70.760  1.00 21.10  ? 429  PRO D CA  1 
ATOM   14019 C C   . PRO D 1 436 ? -30.993 -4.183  -71.300  1.00 20.33  ? 429  PRO D C   1 
ATOM   14020 O O   . PRO D 1 436 ? -31.038 -3.196  -70.571  1.00 18.87  ? 429  PRO D O   1 
ATOM   14021 C CB  . PRO D 1 436 ? -32.710 -5.995  -71.024  1.00 21.13  ? 429  PRO D CB  1 
ATOM   14022 C CG  . PRO D 1 436 ? -33.296 -6.330  -69.673  1.00 20.86  ? 429  PRO D CG  1 
ATOM   14023 C CD  . PRO D 1 436 ? -32.411 -5.646  -68.645  1.00 21.50  ? 429  PRO D CD  1 
ATOM   14024 N N   . PRO D 1 437 ? -30.724 -4.056  -72.611  1.00 20.67  ? 430  PRO D N   1 
ATOM   14025 C CA  . PRO D 1 437 ? -30.731 -2.751  -73.257  1.00 19.89  ? 430  PRO D CA  1 
ATOM   14026 C C   . PRO D 1 437 ? -32.036 -2.007  -72.956  1.00 18.85  ? 430  PRO D C   1 
ATOM   14027 O O   . PRO D 1 437 ? -33.047 -2.647  -72.921  1.00 17.86  ? 430  PRO D O   1 
ATOM   14028 C CB  . PRO D 1 437 ? -30.661 -3.111  -74.741  1.00 21.70  ? 430  PRO D CB  1 
ATOM   14029 C CG  . PRO D 1 437 ? -29.931 -4.435  -74.766  1.00 22.35  ? 430  PRO D CG  1 
ATOM   14030 C CD  . PRO D 1 437 ? -30.394 -5.157  -73.523  1.00 21.97  ? 430  PRO D CD  1 
ATOM   14031 N N   . LEU D 1 438 ? -31.977 -0.688  -72.778  1.00 18.03  ? 431  LEU D N   1 
ATOM   14032 C CA  . LEU D 1 438 ? -33.173 0.162   -72.559  1.00 17.72  ? 431  LEU D CA  1 
ATOM   14033 C C   . LEU D 1 438 ? -34.073 0.038   -73.799  1.00 19.55  ? 431  LEU D C   1 
ATOM   14034 O O   . LEU D 1 438 ? -35.272 0.302   -73.691  1.00 17.78  ? 431  LEU D O   1 
ATOM   14035 C CB  . LEU D 1 438 ? -32.746 1.610   -72.306  1.00 17.70  ? 431  LEU D CB  1 
ATOM   14036 C CG  . LEU D 1 438 ? -31.669 1.805   -71.230  1.00 19.77  ? 431  LEU D CG  1 
ATOM   14037 C CD1 . LEU D 1 438 ? -31.614 3.250   -70.744  1.00 19.48  ? 431  LEU D CD1 1 
ATOM   14038 C CD2 . LEU D 1 438 ? -31.868 0.855   -70.050  1.00 20.07  ? 431  LEU D CD2 1 
ATOM   14039 N N   . THR D 1 439 ? -33.495 -0.395  -74.925  1.00 20.69  ? 432  THR D N   1 
ATOM   14040 C CA  . THR D 1 439 ? -34.139 -0.544  -76.251  1.00 20.95  ? 432  THR D CA  1 
ATOM   14041 C C   . THR D 1 439 ? -34.869 -1.885  -76.370  1.00 20.86  ? 432  THR D C   1 
ATOM   14042 O O   . THR D 1 439 ? -35.505 -2.103  -77.429  1.00 22.43  ? 432  THR D O   1 
ATOM   14043 C CB  . THR D 1 439 ? -33.087 -0.385  -77.348  1.00 20.36  ? 432  THR D CB  1 
ATOM   14044 O OG1 . THR D 1 439 ? -32.057 -1.334  -77.074  1.00 21.59  ? 432  THR D OG1 1 
ATOM   14045 C CG2 . THR D 1 439 ? -32.523 1.017   -77.397  1.00 20.48  ? 432  THR D CG2 1 
ATOM   14046 N N   . LEU D 1 440 ? -34.815 -2.743  -75.355  1.00 19.38  ? 433  LEU D N   1 
ATOM   14047 C CA  . LEU D 1 440 ? -35.565 -4.022  -75.380  1.00 21.13  ? 433  LEU D CA  1 
ATOM   14048 C C   . LEU D 1 440 ? -37.030 -3.729  -75.742  1.00 21.99  ? 433  LEU D C   1 
ATOM   14049 O O   . LEU D 1 440 ? -37.624 -2.847  -75.123  1.00 22.30  ? 433  LEU D O   1 
ATOM   14050 C CB  . LEU D 1 440 ? -35.465 -4.712  -74.021  1.00 21.60  ? 433  LEU D CB  1 
ATOM   14051 C CG  . LEU D 1 440 ? -35.928 -6.164  -74.020  1.00 21.99  ? 433  LEU D CG  1 
ATOM   14052 C CD1 . LEU D 1 440 ? -34.965 -7.036  -74.796  1.00 22.78  ? 433  LEU D CD1 1 
ATOM   14053 C CD2 . LEU D 1 440 ? -36.088 -6.680  -72.598  1.00 22.80  ? 433  LEU D CD2 1 
ATOM   14054 N N   . THR D 1 441 ? -37.592 -4.422  -76.722  1.00 21.76  ? 434  THR D N   1 
ATOM   14055 C CA  . THR D 1 441 ? -38.968 -4.147  -77.197  1.00 24.07  ? 434  THR D CA  1 
ATOM   14056 C C   . THR D 1 441 ? -39.964 -4.751  -76.210  1.00 27.40  ? 434  THR D C   1 
ATOM   14057 O O   . THR D 1 441 ? -39.588 -5.691  -75.479  1.00 28.58  ? 434  THR D O   1 
ATOM   14058 C CB  . THR D 1 441 ? -39.249 -4.696  -78.600  1.00 23.72  ? 434  THR D CB  1 
ATOM   14059 O OG1 . THR D 1 441 ? -39.341 -6.120  -78.517  1.00 24.77  ? 434  THR D OG1 1 
ATOM   14060 C CG2 . THR D 1 441 ? -38.207 -4.289  -79.614  1.00 23.55  ? 434  THR D CG2 1 
ATOM   14061 N N   . ILE D 1 442 ? -41.198 -4.254  -76.223  1.00 30.24  ? 435  ILE D N   1 
ATOM   14062 C CA  . ILE D 1 442 ? -42.264 -4.765  -75.324  1.00 31.06  ? 435  ILE D CA  1 
ATOM   14063 C C   . ILE D 1 442 ? -42.437 -6.252  -75.601  1.00 28.61  ? 435  ILE D C   1 
ATOM   14064 O O   . ILE D 1 442 ? -42.567 -7.000  -74.653  1.00 25.07  ? 435  ILE D O   1 
ATOM   14065 C CB  . ILE D 1 442 ? -43.576 -3.996  -75.508  1.00 35.39  ? 435  ILE D CB  1 
ATOM   14066 C CG1 . ILE D 1 442 ? -43.363 -2.485  -75.366  1.00 39.03  ? 435  ILE D CG1 1 
ATOM   14067 C CG2 . ILE D 1 442 ? -44.614 -4.521  -74.524  1.00 35.81  ? 435  ILE D CG2 1 
ATOM   14068 C CD1 . ILE D 1 442 ? -42.908 -2.037  -73.980  1.00 37.30  ? 435  ILE D CD1 1 
ATOM   14069 N N   . GLU D 1 443 ? -42.417 -6.656  -76.864  1.00 30.15  ? 436  GLU D N   1 
ATOM   14070 C CA  . GLU D 1 443 ? -42.556 -8.090  -77.210  1.00 34.76  ? 436  GLU D CA  1 
ATOM   14071 C C   . GLU D 1 443 ? -41.392 -8.866  -76.596  1.00 32.07  ? 436  GLU D C   1 
ATOM   14072 O O   . GLU D 1 443 ? -41.661 -9.913  -76.029  1.00 35.87  ? 436  GLU D O   1 
ATOM   14073 C CB  . GLU D 1 443 ? -42.627 -8.355  -78.710  1.00 44.98  ? 436  GLU D CB  1 
ATOM   14074 C CG  . GLU D 1 443 ? -43.404 -9.640  -79.005  1.00 53.74  ? 436  GLU D CG  1 
ATOM   14075 C CD  . GLU D 1 443 ? -42.909 -10.490 -80.171  1.00 61.28  ? 436  GLU D CD  1 
ATOM   14076 O OE1 . GLU D 1 443 ? -42.404 -9.901  -81.162  1.00 62.44  ? 436  GLU D OE1 1 
ATOM   14077 O OE2 . GLU D 1 443 ? -43.039 -11.752 -80.094  1.00 67.32  ? 436  GLU D OE2 1 
ATOM   14078 N N   . GLN D 1 444 ? -40.156 -8.378  -76.693  1.00 26.70  ? 437  GLN D N   1 
ATOM   14079 C CA  . GLN D 1 444 ? -38.997 -9.084  -76.094  1.00 27.44  ? 437  GLN D CA  1 
ATOM   14080 C C   . GLN D 1 444 ? -39.199 -9.163  -74.579  1.00 25.33  ? 437  GLN D C   1 
ATOM   14081 O O   . GLN D 1 444 ? -39.042 -10.269 -74.034  1.00 21.84  ? 437  GLN D O   1 
ATOM   14082 C CB  . GLN D 1 444 ? -37.671 -8.436  -76.495  1.00 29.60  ? 437  GLN D CB  1 
ATOM   14083 C CG  . GLN D 1 444 ? -37.302 -8.783  -77.933  1.00 30.91  ? 437  GLN D CG  1 
ATOM   14084 C CD  . GLN D 1 444 ? -36.300 -7.848  -78.561  1.00 31.26  ? 437  GLN D CD  1 
ATOM   14085 O OE1 . GLN D 1 444 ? -36.207 -6.662  -78.234  1.00 29.33  ? 437  GLN D OE1 1 
ATOM   14086 N NE2 . GLN D 1 444 ? -35.533 -8.394  -79.487  1.00 33.09  ? 437  GLN D NE2 1 
ATOM   14087 N N   . CYS D 1 445 ? -39.582 -8.059  -73.931  1.00 25.99  ? 438  CYS D N   1 
ATOM   14088 C CA  . CYS D 1 445 ? -39.917 -8.034  -72.477  1.00 27.76  ? 438  CYS D CA  1 
ATOM   14089 C C   . CYS D 1 445 ? -40.813 -9.237  -72.152  1.00 27.67  ? 438  CYS D C   1 
ATOM   14090 O O   . CYS D 1 445 ? -40.449 -10.008 -71.275  1.00 27.68  ? 438  CYS D O   1 
ATOM   14091 C CB  . CYS D 1 445 ? -40.613 -6.746  -72.044  1.00 26.99  ? 438  CYS D CB  1 
ATOM   14092 S SG  . CYS D 1 445 ? -39.557 -5.269  -72.082  1.00 26.41  ? 438  CYS D SG  1 
ATOM   14093 N N   . GLU D 1 446 ? -41.907 -9.414  -72.891  1.00 28.66  ? 439  GLU D N   1 
ATOM   14094 C CA  . GLU D 1 446 ? -42.881 -10.520 -72.695  1.00 30.92  ? 439  GLU D CA  1 
ATOM   14095 C C   . GLU D 1 446 ? -42.187 -11.867 -72.912  1.00 29.62  ? 439  GLU D C   1 
ATOM   14096 O O   . GLU D 1 446 ? -42.422 -12.770 -72.109  1.00 32.50  ? 439  GLU D O   1 
ATOM   14097 C CB  . GLU D 1 446 ? -44.083 -10.365 -73.633  1.00 33.00  ? 439  GLU D CB  1 
ATOM   14098 C CG  . GLU D 1 446 ? -44.979 -9.186  -73.266  1.00 35.60  ? 439  GLU D CG  1 
ATOM   14099 C CD  . GLU D 1 446 ? -46.176 -8.926  -74.178  1.00 38.52  ? 439  GLU D CD  1 
ATOM   14100 O OE1 . GLU D 1 446 ? -46.210 -9.465  -75.309  1.00 38.13  ? 439  GLU D OE1 1 
ATOM   14101 O OE2 . GLU D 1 446 ? -47.096 -8.191  -73.751  1.00 39.63  ? 439  GLU D OE2 1 
ATOM   14102 N N   . LEU D 1 447 ? -41.371 -12.001 -73.954  1.00 27.99  ? 440  LEU D N   1 
ATOM   14103 C CA  . LEU D 1 447 ? -40.636 -13.261 -74.267  1.00 29.14  ? 440  LEU D CA  1 
ATOM   14104 C C   . LEU D 1 447 ? -39.700 -13.599 -73.107  1.00 28.18  ? 440  LEU D C   1 
ATOM   14105 O O   . LEU D 1 447 ? -39.567 -14.792 -72.790  1.00 28.37  ? 440  LEU D O   1 
ATOM   14106 C CB  . LEU D 1 447 ? -39.839 -13.107 -75.567  1.00 30.44  ? 440  LEU D CB  1 
ATOM   14107 C CG  . LEU D 1 447 ? -40.682 -12.966 -76.832  1.00 32.22  ? 440  LEU D CG  1 
ATOM   14108 C CD1 . LEU D 1 447 ? -39.800 -12.808 -78.061  1.00 33.79  ? 440  LEU D CD1 1 
ATOM   14109 C CD2 . LEU D 1 447 ? -41.621 -14.153 -76.988  1.00 32.59  ? 440  LEU D CD2 1 
ATOM   14110 N N   . VAL D 1 448 ? -39.081 -12.582 -72.506  1.00 26.28  ? 441  VAL D N   1 
ATOM   14111 C CA  . VAL D 1 448 ? -38.142 -12.751 -71.362  1.00 28.30  ? 441  VAL D CA  1 
ATOM   14112 C C   . VAL D 1 448 ? -38.909 -13.383 -70.189  1.00 26.71  ? 441  VAL D C   1 
ATOM   14113 O O   . VAL D 1 448 ? -38.458 -14.406 -69.647  1.00 22.95  ? 441  VAL D O   1 
ATOM   14114 C CB  . VAL D 1 448 ? -37.481 -11.408 -70.988  1.00 29.30  ? 441  VAL D CB  1 
ATOM   14115 C CG1 . VAL D 1 448 ? -36.792 -11.458 -69.638  1.00 29.80  ? 441  VAL D CG1 1 
ATOM   14116 C CG2 . VAL D 1 448 ? -36.512 -10.945 -72.058  1.00 27.34  ? 441  VAL D CG2 1 
ATOM   14117 N N   . ILE D 1 449 ? -40.065 -12.822 -69.855  1.00 29.30  ? 442  ILE D N   1 
ATOM   14118 C CA  . ILE D 1 449 ? -40.934 -13.313 -68.751  1.00 28.69  ? 442  ILE D CA  1 
ATOM   14119 C C   . ILE D 1 449 ? -41.357 -14.757 -69.043  1.00 28.58  ? 442  ILE D C   1 
ATOM   14120 O O   . ILE D 1 449 ? -41.319 -15.567 -68.109  1.00 27.87  ? 442  ILE D O   1 
ATOM   14121 C CB  . ILE D 1 449 ? -42.135 -12.375 -68.559  1.00 29.35  ? 442  ILE D CB  1 
ATOM   14122 C CG1 . ILE D 1 449 ? -41.714 -10.955 -68.167  1.00 29.02  ? 442  ILE D CG1 1 
ATOM   14123 C CG2 . ILE D 1 449 ? -43.104 -12.974 -67.554  1.00 30.29  ? 442  ILE D CG2 1 
ATOM   14124 C CD1 . ILE D 1 449 ? -40.872 -10.875 -66.924  1.00 29.19  ? 442  ILE D CD1 1 
ATOM   14125 N N   . LYS D 1 450 ? -41.706 -15.075 -70.291  1.00 31.67  ? 443  LYS D N   1 
ATOM   14126 C CA  . LYS D 1 450 ? -42.148 -16.440 -70.679  1.00 35.73  ? 443  LYS D CA  1 
ATOM   14127 C C   . LYS D 1 450 ? -40.968 -17.403 -70.538  1.00 34.54  ? 443  LYS D C   1 
ATOM   14128 O O   . LYS D 1 450 ? -41.181 -18.516 -70.016  1.00 36.13  ? 443  LYS D O   1 
ATOM   14129 C CB  . LYS D 1 450 ? -42.661 -16.486 -72.120  1.00 39.55  ? 443  LYS D CB  1 
ATOM   14130 C CG  . LYS D 1 450 ? -43.985 -15.785 -72.421  1.00 48.03  ? 443  LYS D CG  1 
ATOM   14131 C CD  . LYS D 1 450 ? -44.015 -15.011 -73.783  1.00 56.02  ? 443  LYS D CD  1 
ATOM   14132 C CE  . LYS D 1 450 ? -45.151 -15.322 -74.751  1.00 61.04  ? 443  LYS D CE  1 
ATOM   14133 N NZ  . LYS D 1 450 ? -46.453 -14.772 -74.300  1.00 66.83  ? 443  LYS D NZ  1 
ATOM   14134 N N   . ALA D 1 451 ? -39.775 -16.989 -70.974  1.00 31.40  ? 444  ALA D N   1 
ATOM   14135 C CA  . ALA D 1 451 ? -38.522 -17.768 -70.833  1.00 30.86  ? 444  ALA D CA  1 
ATOM   14136 C C   . ALA D 1 451 ? -38.242 -18.040 -69.354  1.00 29.43  ? 444  ALA D C   1 
ATOM   14137 O O   . ALA D 1 451 ? -37.919 -19.195 -69.007  1.00 30.18  ? 444  ALA D O   1 
ATOM   14138 C CB  . ALA D 1 451 ? -37.376 -17.038 -71.469  1.00 30.55  ? 444  ALA D CB  1 
ATOM   14139 N N   . ALA D 1 452 ? -38.373 -17.020 -68.508  1.00 28.04  ? 445  ALA D N   1 
ATOM   14140 C CA  . ALA D 1 452 ? -38.142 -17.153 -67.053  1.00 29.26  ? 445  ALA D CA  1 
ATOM   14141 C C   . ALA D 1 452 ? -39.111 -18.199 -66.508  1.00 30.14  ? 445  ALA D C   1 
ATOM   14142 O O   . ALA D 1 452 ? -38.667 -19.091 -65.762  1.00 30.95  ? 445  ALA D O   1 
ATOM   14143 C CB  . ALA D 1 452 ? -38.296 -15.824 -66.366  1.00 29.66  ? 445  ALA D CB  1 
ATOM   14144 N N   A ARG D 1 453 ? -40.392 -18.098 -66.882  0.50 29.02  ? 446  ARG D N   1 
ATOM   14145 N N   B ARG D 1 453 ? -40.392 -18.077 -66.875  0.50 29.30  ? 446  ARG D N   1 
ATOM   14146 C CA  A ARG D 1 453 ? -41.459 -19.017 -66.414  0.50 27.55  ? 446  ARG D CA  1 
ATOM   14147 C CA  B ARG D 1 453 ? -41.482 -18.980 -66.432  0.50 27.97  ? 446  ARG D CA  1 
ATOM   14148 C C   A ARG D 1 453 ? -41.086 -20.443 -66.812  0.50 27.86  ? 446  ARG D C   1 
ATOM   14149 C C   B ARG D 1 453 ? -41.099 -20.418 -66.810  0.50 28.12  ? 446  ARG D C   1 
ATOM   14150 O O   A ARG D 1 453 ? -41.073 -21.320 -65.943  0.50 27.14  ? 446  ARG D O   1 
ATOM   14151 O O   B ARG D 1 453 ? -41.057 -21.275 -65.906  0.50 27.41  ? 446  ARG D O   1 
ATOM   14152 C CB  A ARG D 1 453 ? -42.806 -18.607 -67.016  0.50 27.01  ? 446  ARG D CB  1 
ATOM   14153 C CB  B ARG D 1 453 ? -42.797 -18.506 -67.059  0.50 27.72  ? 446  ARG D CB  1 
ATOM   14154 C CG  A ARG D 1 453 ? -43.998 -19.410 -66.530  0.50 26.04  ? 446  ARG D CG  1 
ATOM   14155 C CG  B ARG D 1 453 ? -44.050 -19.071 -66.407  0.50 27.03  ? 446  ARG D CG  1 
ATOM   14156 C CD  A ARG D 1 453 ? -45.311 -18.797 -67.025  0.50 24.84  ? 446  ARG D CD  1 
ATOM   14157 C CD  B ARG D 1 453 ? -45.351 -18.498 -66.957  0.50 25.97  ? 446  ARG D CD  1 
ATOM   14158 N NE  A ARG D 1 453 ? -45.723 -17.569 -66.336  0.50 23.02  ? 446  ARG D NE  1 
ATOM   14159 N NE  B ARG D 1 453 ? -45.563 -17.064 -66.772  0.50 24.44  ? 446  ARG D NE  1 
ATOM   14160 C CZ  A ARG D 1 453 ? -46.165 -17.515 -65.083  0.50 21.76  ? 446  ARG D CZ  1 
ATOM   14161 C CZ  B ARG D 1 453 ? -45.769 -16.201 -67.769  0.50 23.14  ? 446  ARG D CZ  1 
ATOM   14162 N NH1 A ARG D 1 453 ? -46.241 -18.617 -64.366  0.50 21.57  ? 446  ARG D NH1 1 
ATOM   14163 N NH1 B ARG D 1 453 ? -45.773 -16.614 -69.026  0.50 21.90  ? 446  ARG D NH1 1 
ATOM   14164 N NH2 A ARG D 1 453 ? -46.519 -16.367 -64.534  0.50 21.31  ? 446  ARG D NH2 1 
ATOM   14165 N NH2 B ARG D 1 453 ? -45.968 -14.925 -67.502  0.50 22.46  ? 446  ARG D NH2 1 
ATOM   14166 N N   . LYS D 1 454 ? -40.775 -20.649 -68.087  1.00 28.86  ? 447  LYS D N   1 
ATOM   14167 C CA  . LYS D 1 454 ? -40.409 -21.983 -68.626  1.00 34.46  ? 447  LYS D CA  1 
ATOM   14168 C C   . LYS D 1 454 ? -39.210 -22.523 -67.842  1.00 36.34  ? 447  LYS D C   1 
ATOM   14169 O O   . LYS D 1 454 ? -39.209 -23.718 -67.509  1.00 37.68  ? 447  LYS D O   1 
ATOM   14170 C CB  . LYS D 1 454 ? -40.182 -21.883 -70.141  1.00 38.54  ? 447  LYS D CB  1 
ATOM   14171 C CG  . LYS D 1 454 ? -41.468 -21.967 -70.951  1.00 45.56  ? 447  LYS D CG  1 
ATOM   14172 C CD  . LYS D 1 454 ? -41.287 -21.864 -72.444  1.00 54.45  ? 447  LYS D CD  1 
ATOM   14173 C CE  . LYS D 1 454 ? -40.947 -20.455 -72.878  1.00 58.54  ? 447  LYS D CE  1 
ATOM   14174 N NZ  . LYS D 1 454 ? -40.995 -20.293 -74.349  1.00 56.10  ? 447  LYS D NZ  1 
ATOM   14175 N N   . ALA D 1 455 ? -38.243 -21.665 -67.523  1.00 36.78  ? 448  ALA D N   1 
ATOM   14176 C CA  . ALA D 1 455 ? -37.000 -22.042 -66.814  1.00 40.51  ? 448  ALA D CA  1 
ATOM   14177 C C   . ALA D 1 455 ? -37.336 -22.559 -65.409  1.00 42.88  ? 448  ALA D C   1 
ATOM   14178 O O   . ALA D 1 455 ? -36.857 -23.645 -65.042  1.00 42.28  ? 448  ALA D O   1 
ATOM   14179 C CB  . ALA D 1 455 ? -36.067 -20.860 -66.766  1.00 43.60  ? 448  ALA D CB  1 
ATOM   14180 N N   . LEU D 1 456 ? -38.147 -21.812 -64.657  1.00 44.62  ? 449  LEU D N   1 
ATOM   14181 C CA  . LEU D 1 456 ? -38.533 -22.143 -63.260  1.00 42.25  ? 449  LEU D CA  1 
ATOM   14182 C C   . LEU D 1 456 ? -39.333 -23.449 -63.229  1.00 42.52  ? 449  LEU D C   1 
ATOM   14183 O O   . LEU D 1 456 ? -39.064 -24.270 -62.342  1.00 43.32  ? 449  LEU D O   1 
ATOM   14184 C CB  . LEU D 1 456 ? -39.337 -20.980 -62.679  1.00 42.25  ? 449  LEU D CB  1 
ATOM   14185 C CG  . LEU D 1 456 ? -38.523 -19.707 -62.430  1.00 43.74  ? 449  LEU D CG  1 
ATOM   14186 C CD1 . LEU D 1 456 ? -39.417 -18.530 -62.109  1.00 44.74  ? 449  LEU D CD1 1 
ATOM   14187 C CD2 . LEU D 1 456 ? -37.514 -19.903 -61.306  1.00 48.20  ? 449  LEU D CD2 1 
ATOM   14188 N N   . ALA D 1 457 ? -40.259 -23.642 -64.169  1.00 44.38  ? 450  ALA D N   1 
ATOM   14189 C CA  . ALA D 1 457 ? -41.075 -24.871 -64.287  1.00 47.11  ? 450  ALA D CA  1 
ATOM   14190 C C   . ALA D 1 457 ? -40.167 -26.087 -64.509  1.00 51.02  ? 450  ALA D C   1 
ATOM   14191 O O   . ALA D 1 457 ? -40.385 -27.123 -63.839  1.00 61.99  ? 450  ALA D O   1 
ATOM   14192 C CB  . ALA D 1 457 ? -42.087 -24.722 -65.388  1.00 46.46  ? 450  ALA D CB  1 
ATOM   14193 N N   . ALA D 1 458 ? -39.174 -25.970 -65.396  1.00 51.05  ? 451  ALA D N   1 
ATOM   14194 C CA  . ALA D 1 458 ? -38.195 -27.043 -65.700  1.00 50.48  ? 451  ALA D CA  1 
ATOM   14195 C C   . ALA D 1 458 ? -37.337 -27.331 -64.464  1.00 51.19  ? 451  ALA D C   1 
ATOM   14196 O O   . ALA D 1 458 ? -37.088 -28.507 -64.179  1.00 55.83  ? 451  ALA D O   1 
ATOM   14197 C CB  . ALA D 1 458 ? -37.349 -26.654 -66.880  1.00 50.75  ? 451  ALA D CB  1 
ATOM   14198 N N   . MET D 1 459 ? -36.906 -26.284 -63.760  1.00 49.60  ? 452  MET D N   1 
ATOM   14199 C CA  . MET D 1 459 ? -36.101 -26.373 -62.513  1.00 49.42  ? 452  MET D CA  1 
ATOM   14200 C C   . MET D 1 459 ? -36.887 -27.127 -61.433  1.00 49.91  ? 452  MET D C   1 
ATOM   14201 O O   . MET D 1 459 ? -36.279 -27.971 -60.722  1.00 49.78  ? 452  MET D O   1 
ATOM   14202 C CB  . MET D 1 459 ? -35.733 -24.975 -62.011  1.00 48.57  ? 452  MET D CB  1 
ATOM   14203 C CG  . MET D 1 459 ? -34.616 -24.326 -62.807  1.00 46.43  ? 452  MET D CG  1 
ATOM   14204 S SD  . MET D 1 459 ? -34.580 -22.529 -62.608  1.00 43.22  ? 452  MET D SD  1 
ATOM   14205 C CE  . MET D 1 459 ? -34.186 -22.387 -60.867  1.00 36.19  ? 452  MET D CE  1 
ATOM   14206 N N   . ARG D 1 460 ? -38.184 -26.839 -61.300  1.00 53.94  ? 453  ARG D N   1 
ATOM   14207 C CA  . ARG D 1 460 ? -39.055 -27.490 -60.285  1.00 57.09  ? 453  ARG D CA  1 
ATOM   14208 C C   . ARG D 1 460 ? -39.074 -28.999 -60.552  1.00 60.01  ? 453  ARG D C   1 
ATOM   14209 O O   . ARG D 1 460 ? -38.852 -29.758 -59.592  1.00 62.62  ? 453  ARG D O   1 
ATOM   14210 C CB  . ARG D 1 460 ? -40.460 -26.879 -60.289  1.00 55.69  ? 453  ARG D CB  1 
ATOM   14211 C CG  . ARG D 1 460 ? -41.396 -27.499 -59.263  1.00 54.93  ? 453  ARG D CG  1 
ATOM   14212 C CD  . ARG D 1 460 ? -42.718 -26.757 -59.170  1.00 50.41  ? 453  ARG D CD  1 
ATOM   14213 N NE  . ARG D 1 460 ? -42.636 -25.592 -58.302  1.00 47.94  ? 453  ARG D NE  1 
ATOM   14214 C CZ  . ARG D 1 460 ? -43.558 -24.639 -58.221  1.00 42.47  ? 453  ARG D CZ  1 
ATOM   14215 N NH1 . ARG D 1 460 ? -44.642 -24.699 -58.969  1.00 41.51  ? 453  ARG D NH1 1 
ATOM   14216 N NH2 . ARG D 1 460 ? -43.386 -23.610 -57.408  1.00 42.05  ? 453  ARG D NH2 1 
ATOM   14217 N N   . VAL D 1 461 ? -39.272 -29.391 -61.815  1.00 65.41  ? 454  VAL D N   1 
ATOM   14218 C CA  . VAL D 1 461 ? -39.278 -30.812 -62.278  1.00 76.70  ? 454  VAL D CA  1 
ATOM   14219 C C   . VAL D 1 461 ? -37.953 -31.463 -61.866  1.00 83.58  ? 454  VAL D C   1 
ATOM   14220 O O   . VAL D 1 461 ? -38.009 -32.503 -61.186  1.00 99.71  ? 454  VAL D O   1 
ATOM   14221 C CB  . VAL D 1 461 ? -39.538 -30.929 -63.797  1.00 83.98  ? 454  VAL D CB  1 
ATOM   14222 C CG1 . VAL D 1 461 ? -39.233 -32.330 -64.332  1.00 83.03  ? 454  VAL D CG1 1 
ATOM   14223 C CG2 . VAL D 1 461 ? -40.961 -30.516 -64.161  1.00 85.92  ? 454  VAL D CG2 1 
ATOM   14224 N N   . SER D 1 462 ? -36.812 -30.870 -62.236  1.00 87.95  ? 455  SER D N   1 
ATOM   14225 C CA  . SER D 1 462 ? -35.446 -31.349 -61.884  1.00 95.52  ? 455  SER D CA  1 
ATOM   14226 C C   . SER D 1 462 ? -35.401 -31.700 -60.396  1.00 101.21 ? 455  SER D C   1 
ATOM   14227 O O   . SER D 1 462 ? -35.044 -32.844 -60.065  1.00 108.99 ? 455  SER D O   1 
ATOM   14228 C CB  . SER D 1 462 ? -34.385 -30.330 -62.215  1.00 98.60  ? 455  SER D CB  1 
ATOM   14229 O OG  . SER D 1 462 ? -34.537 -29.840 -63.535  1.00 100.08 ? 455  SER D OG  1 
ATOM   14230 N N   . VAL D 1 463 ? -35.761 -30.745 -59.534  1.00 97.00  ? 456  VAL D N   1 
ATOM   14231 C CA  . VAL D 1 463 ? -35.782 -30.931 -58.052  1.00 93.97  ? 456  VAL D CA  1 
ATOM   14232 C C   . VAL D 1 463 ? -36.717 -32.114 -57.723  1.00 108.28 ? 456  VAL D C   1 
ATOM   14233 O O   . VAL D 1 463 ? -36.226 -33.176 -57.309  1.00 125.49 ? 456  VAL D O   1 
ATOM   14234 C CB  . VAL D 1 463 ? -36.186 -29.631 -57.338  1.00 85.34  ? 456  VAL D CB  1 
ATOM   14235 C CG1 . VAL D 1 463 ? -36.440 -29.881 -55.859  1.00 88.63  ? 456  VAL D CG1 1 
ATOM   14236 C CG2 . VAL D 1 463 ? -35.147 -28.538 -57.531  1.00 76.66  ? 456  VAL D CG2 1 
ATOM   14237 N N   . GLU D 1 464 ? -38.015 -31.973 -58.005  1.00 117.17 ? 457  GLU D N   1 
ATOM   14238 C CA  . GLU D 1 464 ? -39.075 -33.004 -57.772  1.00 123.43 ? 457  GLU D CA  1 
ATOM   14239 C C   . GLU D 1 464 ? -38.740 -34.371 -58.405  1.00 134.82 ? 457  GLU D C   1 
ATOM   14240 O O   . GLU D 1 464 ? -39.522 -35.295 -58.127  1.00 133.21 ? 457  GLU D O   1 
ATOM   14241 C CB  . GLU D 1 464 ? -40.415 -32.542 -58.355  1.00 118.34 ? 457  GLU D CB  1 
ATOM   14242 C CG  . GLU D 1 464 ? -41.016 -31.325 -57.654  1.00 116.19 ? 457  GLU D CG  1 
ATOM   14243 C CD  . GLU D 1 464 ? -42.215 -30.714 -58.353  1.00 113.70 ? 457  GLU D CD  1 
ATOM   14244 O OE1 . GLU D 1 464 ? -42.280 -30.775 -59.595  1.00 114.47 ? 457  GLU D OE1 1 
ATOM   14245 O OE2 . GLU D 1 464 ? -43.089 -30.160 -57.649  1.00 106.01 ? 457  GLU D OE2 1 
ATOM   14246 N N   . GLU D 1 465 ? -37.767 -34.498 -59.320  1.00 143.78 ? 458  GLU D N   1 
ATOM   14247 C CA  . GLU D 1 465 ? -37.245 -35.798 -59.829  1.00 139.60 ? 458  GLU D CA  1 
ATOM   14248 C C   . GLU D 1 465 ? -36.875 -36.690 -58.625  1.00 147.34 ? 458  GLU D C   1 
ATOM   14249 O O   . GLU D 1 465 ? -35.665 -36.819 -58.314  1.00 151.78 ? 458  GLU D O   1 
ATOM   14250 C CB  . GLU D 1 465 ? -36.031 -35.634 -60.754  1.00 131.31 ? 458  GLU D CB  1 
ATOM   14251 C CG  . GLU D 1 465 ? -36.298 -34.980 -62.101  1.00 120.87 ? 458  GLU D CG  1 
ATOM   14252 C CD  . GLU D 1 465 ? -37.590 -35.327 -62.827  1.00 117.71 ? 458  GLU D CD  1 
ATOM   14253 O OE1 . GLU D 1 465 ? -37.495 -36.022 -63.838  1.00 113.36 ? 458  GLU D OE1 1 
ATOM   14254 O OE2 . GLU D 1 465 ? -38.682 -34.904 -62.381  1.00 109.11 ? 458  GLU D OE2 1 
ATOM   14255 N N   . ALA D 1 466 ? -37.885 -37.335 -58.016  1.00 141.62 ? 459  ALA D N   1 
ATOM   14256 C CA  . ALA D 1 466 ? -37.829 -38.118 -56.752  1.00 128.08 ? 459  ALA D CA  1 
ATOM   14257 C C   . ALA D 1 466 ? -36.756 -37.534 -55.821  1.00 140.27 ? 459  ALA D C   1 
ATOM   14258 O O   . ALA D 1 466 ? -35.809 -38.267 -55.477  1.00 140.05 ? 459  ALA D O   1 
ATOM   14259 C CB  . ALA D 1 466 ? -37.614 -39.590 -57.033  1.00 114.46 ? 459  ALA D CB  1 
ATOM   14260 N N   . LEU D 1 467 ? -36.911 -36.262 -55.433  1.00 151.15 ? 460  LEU D N   1 
ATOM   14261 C CA  . LEU D 1 467 ? -36.076 -35.547 -54.422  1.00 150.10 ? 460  LEU D CA  1 
ATOM   14262 C C   . LEU D 1 467 ? -36.665 -34.143 -54.196  1.00 151.21 ? 460  LEU D C   1 
ATOM   14263 O O   . LEU D 1 467 ? -37.427 -33.681 -55.056  1.00 153.23 ? 460  LEU D O   1 
ATOM   14264 C CB  . LEU D 1 467 ? -34.612 -35.483 -54.888  1.00 145.56 ? 460  LEU D CB  1 
ATOM   14265 C CG  . LEU D 1 467 ? -34.352 -34.814 -56.241  1.00 138.77 ? 460  LEU D CG  1 
ATOM   14266 C CD1 . LEU D 1 467 ? -34.115 -33.316 -56.072  1.00 138.61 ? 460  LEU D CD1 1 
ATOM   14267 C CD2 . LEU D 1 467 ? -33.163 -35.448 -56.951  1.00 124.37 ? 460  LEU D CD2 1 
ATOM   14268 N N   . GLU D 1 468 ? -36.336 -33.507 -53.068  1.00 145.63 ? 461  GLU D N   1 
ATOM   14269 C CA  . GLU D 1 468 ? -36.778 -32.128 -52.691  1.00 136.40 ? 461  GLU D CA  1 
ATOM   14270 C C   . GLU D 1 468 ? -36.670 -31.958 -51.167  1.00 134.36 ? 461  GLU D C   1 
ATOM   14271 O O   . GLU D 1 468 ? -35.751 -31.225 -50.729  1.00 124.79 ? 461  GLU D O   1 
ATOM   14272 C CB  . GLU D 1 468 ? -38.200 -31.825 -53.174  1.00 124.42 ? 461  GLU D CB  1 
ATOM   14273 N N   . VAL D 1 469 ? -37.537 -32.631 -50.391  1.00 136.84 ? 462  VAL D N   1 
ATOM   14274 C CA  . VAL D 1 469 ? -37.517 -32.602 -48.895  1.00 134.08 ? 462  VAL D CA  1 
ATOM   14275 C C   . VAL D 1 469 ? -36.137 -33.116 -48.432  1.00 141.95 ? 462  VAL D C   1 
ATOM   14276 O O   . VAL D 1 469 ? -35.464 -33.862 -49.182  1.00 145.70 ? 462  VAL D O   1 
ATOM   14277 C CB  . VAL D 1 469 ? -38.704 -33.365 -48.257  1.00 120.22 ? 462  VAL D CB  1 
ATOM   14278 C CG1 . VAL D 1 469 ? -38.789 -33.166 -46.744  1.00 107.07 ? 462  VAL D CG1 1 
ATOM   14279 C CG2 . VAL D 1 469 ? -40.029 -32.989 -48.914  1.00 115.47 ? 462  VAL D CG2 1 
ATOM   14280 N N   . SER D 1 470 ? -35.690 -32.642 -47.272  1.00 138.22 ? 463  SER D N   1 
ATOM   14281 C CA  . SER D 1 470 ? -34.336 -32.858 -46.695  1.00 125.87 ? 463  SER D CA  1 
ATOM   14282 C C   . SER D 1 470 ? -34.259 -32.118 -45.356  1.00 131.68 ? 463  SER D C   1 
ATOM   14283 O O   . SER D 1 470 ? -33.165 -32.087 -44.786  1.00 159.53 ? 463  SER D O   1 
ATOM   14284 C CB  . SER D 1 470 ? -33.247 -32.417 -47.659  1.00 115.37 ? 463  SER D CB  1 
ATOM   14285 O OG  . SER D 1 470 ? -33.615 -31.242 -48.363  1.00 101.91 ? 463  SER D OG  1 
ATOM   14286 N N   . ALA D 1 471 ? -35.398 -31.606 -44.858  1.00 125.91 ? 464  ALA D N   1 
ATOM   14287 C CA  . ALA D 1 471 ? -35.535 -30.752 -43.652  1.00 123.48 ? 464  ALA D CA  1 
ATOM   14288 C C   . ALA D 1 471 ? -34.769 -31.378 -42.473  1.00 126.54 ? 464  ALA D C   1 
ATOM   14289 O O   . ALA D 1 471 ? -33.640 -30.905 -42.196  1.00 138.24 ? 464  ALA D O   1 
ATOM   14290 C CB  . ALA D 1 471 ? -37.001 -30.524 -43.347  1.00 117.55 ? 464  ALA D CB  1 
ATOM   14291 N N   . LYS D 1 472 ? -35.308 -32.441 -41.855  1.00 129.88 ? 465  LYS D N   1 
ATOM   14292 C CA  . LYS D 1 472 ? -34.687 -33.144 -40.691  1.00 126.30 ? 465  LYS D CA  1 
ATOM   14293 C C   . LYS D 1 472 ? -33.252 -33.564 -41.053  1.00 133.14 ? 465  LYS D C   1 
ATOM   14294 O O   . LYS D 1 472 ? -32.340 -33.337 -40.242  1.00 145.06 ? 465  LYS D O   1 
ATOM   14295 C CB  . LYS D 1 472 ? -35.549 -34.326 -40.232  1.00 116.41 ? 465  LYS D CB  1 
ATOM   14296 C CG  . LYS D 1 472 ? -36.724 -33.956 -39.326  1.00 108.30 ? 465  LYS D CG  1 
ATOM   14297 C CD  . LYS D 1 472 ? -38.104 -34.201 -39.922  1.00 107.85 ? 465  LYS D CD  1 
ATOM   14298 C CE  . LYS D 1 472 ? -38.406 -33.369 -41.151  1.00 107.00 ? 465  LYS D CE  1 
ATOM   14299 N NZ  . LYS D 1 472 ? -39.861 -33.270 -41.412  1.00 105.20 ? 465  LYS D NZ  1 
ATOM   14300 N N   . GLU D 1 473 ? -33.057 -34.095 -42.259  1.00 135.69 ? 466  GLU D N   1 
ATOM   14301 C CA  . GLU D 1 473 ? -31.720 -34.357 -42.873  1.00 130.91 ? 466  GLU D CA  1 
ATOM   14302 C C   . GLU D 1 473 ? -30.768 -33.176 -42.586  1.00 129.42 ? 466  GLU D C   1 
ATOM   14303 O O   . GLU D 1 473 ? -29.627 -33.453 -42.211  1.00 119.37 ? 466  GLU D O   1 
ATOM   14304 C CB  . GLU D 1 473 ? -31.923 -34.752 -44.343  1.00 131.51 ? 466  GLU D CB  1 
ATOM   14305 C CG  . GLU D 1 473 ? -30.937 -34.164 -45.328  1.00 126.29 ? 466  GLU D CG  1 
ATOM   14306 C CD  . GLU D 1 473 ? -31.145 -34.691 -46.736  1.00 124.81 ? 466  GLU D CD  1 
ATOM   14307 O OE1 . GLU D 1 473 ? -31.993 -35.595 -46.940  1.00 124.17 ? 466  GLU D OE1 1 
ATOM   14308 O OE2 . GLU D 1 473 ? -30.468 -34.188 -47.634  1.00 118.64 ? 466  GLU D OE2 1 
ATOM   14309 N N   . GLN D 1 474 ? -31.258 -31.931 -42.636  1.00 130.48 ? 467  GLN D N   1 
ATOM   14310 C CA  . GLN D 1 474 ? -30.511 -30.668 -42.354  1.00 123.01 ? 467  GLN D CA  1 
ATOM   14311 C C   . GLN D 1 474 ? -30.461 -30.372 -40.842  1.00 114.00 ? 467  GLN D C   1 
ATOM   14312 O O   . GLN D 1 474 ? -29.349 -30.177 -40.313  1.00 120.82 ? 467  GLN D O   1 
ATOM   14313 C CB  . GLN D 1 474 ? -31.154 -29.524 -43.159  1.00 127.28 ? 467  GLN D CB  1 
ATOM   14314 C CG  . GLN D 1 474 ? -30.909 -29.640 -44.657  1.00 134.16 ? 467  GLN D CG  1 
ATOM   14315 C CD  . GLN D 1 474 ? -32.122 -29.405 -45.529  1.00 131.58 ? 467  GLN D CD  1 
ATOM   14316 O OE1 . GLN D 1 474 ? -33.190 -29.021 -45.060  1.00 137.03 ? 467  GLN D OE1 1 
ATOM   14317 N NE2 . GLN D 1 474 ? -31.961 -29.658 -46.815  1.00 122.92 ? 467  GLN D NE2 1 
ATOM   14318 N N   . GLN D 1 475 ? -31.622 -30.312 -40.183  1.00 104.36 ? 468  GLN D N   1 
ATOM   14319 C CA  . GLN D 1 475 ? -31.800 -30.106 -38.713  1.00 96.09  ? 468  GLN D CA  1 
ATOM   14320 C C   . GLN D 1 475 ? -30.852 -31.018 -37.914  1.00 92.51  ? 468  GLN D C   1 
ATOM   14321 O O   . GLN D 1 475 ? -30.286 -30.544 -36.914  1.00 87.23  ? 468  GLN D O   1 
ATOM   14322 C CB  . GLN D 1 475 ? -33.267 -30.366 -38.355  1.00 95.25  ? 468  GLN D CB  1 
ATOM   14323 C CG  . GLN D 1 475 ? -33.535 -30.678 -36.888  1.00 90.55  ? 468  GLN D CG  1 
ATOM   14324 C CD  . GLN D 1 475 ? -35.008 -30.847 -36.610  1.00 84.94  ? 468  GLN D CD  1 
ATOM   14325 O OE1 . GLN D 1 475 ? -35.740 -31.516 -37.344  1.00 73.77  ? 468  GLN D OE1 1 
ATOM   14326 N NE2 . GLN D 1 475 ? -35.456 -30.245 -35.520  1.00 84.41  ? 468  GLN D NE2 1 
ATOM   14327 N N   . ASN D 1 476 ? -30.713 -32.285 -38.324  1.00 93.60  ? 469  ASN D N   1 
ATOM   14328 C CA  . ASN D 1 476 ? -29.773 -33.289 -37.751  1.00 95.20  ? 469  ASN D CA  1 
ATOM   14329 C C   . ASN D 1 476 ? -28.352 -32.710 -37.767  1.00 101.28 ? 469  ASN D C   1 
ATOM   14330 O O   . ASN D 1 476 ? -27.670 -32.780 -36.722  1.00 107.25 ? 469  ASN D O   1 
ATOM   14331 C CB  . ASN D 1 476 ? -29.858 -34.619 -38.511  1.00 92.14  ? 469  ASN D CB  1 
ATOM   14332 C CG  . ASN D 1 476 ? -28.694 -35.555 -38.260  1.00 95.16  ? 469  ASN D CG  1 
ATOM   14333 O OD1 . ASN D 1 476 ? -28.359 -35.839 -37.114  1.00 105.92 ? 469  ASN D OD1 1 
ATOM   14334 N ND2 . ASN D 1 476 ? -28.068 -36.043 -39.319  1.00 95.45  ? 469  ASN D ND2 1 
ATOM   14335 N N   . ALA D 1 477 ? -27.934 -32.153 -38.908  1.00 100.96 ? 470  ALA D N   1 
ATOM   14336 C CA  . ALA D 1 477 ? -26.585 -31.582 -39.128  1.00 101.40 ? 470  ALA D CA  1 
ATOM   14337 C C   . ALA D 1 477 ? -26.373 -30.362 -38.217  1.00 102.40 ? 470  ALA D C   1 
ATOM   14338 O O   . ALA D 1 477 ? -25.277 -30.274 -37.627  1.00 106.03 ? 470  ALA D O   1 
ATOM   14339 C CB  . ALA D 1 477 ? -26.389 -31.244 -40.586  1.00 102.78 ? 470  ALA D CB  1 
ATOM   14340 N N   . PHE D 1 478 ? -27.374 -29.476 -38.085  1.00 99.21  ? 471  PHE D N   1 
ATOM   14341 C CA  . PHE D 1 478 ? -27.342 -28.268 -37.209  1.00 98.14  ? 471  PHE D CA  1 
ATOM   14342 C C   . PHE D 1 478 ? -26.934 -28.683 -35.786  1.00 92.54  ? 471  PHE D C   1 
ATOM   14343 O O   . PHE D 1 478 ? -26.010 -28.055 -35.223  1.00 87.09  ? 471  PHE D O   1 
ATOM   14344 C CB  . PHE D 1 478 ? -28.689 -27.528 -37.223  1.00 98.66  ? 471  PHE D CB  1 
ATOM   14345 C CG  . PHE D 1 478 ? -28.798 -26.330 -36.303  1.00 95.25  ? 471  PHE D CG  1 
ATOM   14346 C CD1 . PHE D 1 478 ? -29.132 -26.483 -34.961  1.00 87.62  ? 471  PHE D CD1 1 
ATOM   14347 C CD2 . PHE D 1 478 ? -28.597 -25.044 -36.783  1.00 92.54  ? 471  PHE D CD2 1 
ATOM   14348 C CE1 . PHE D 1 478 ? -29.233 -25.387 -34.117  1.00 77.84  ? 471  PHE D CE1 1 
ATOM   14349 C CE2 . PHE D 1 478 ? -28.699 -23.950 -35.938  1.00 88.33  ? 471  PHE D CE2 1 
ATOM   14350 C CZ  . PHE D 1 478 ? -29.018 -24.123 -34.609  1.00 81.64  ? 471  PHE D CZ  1 
ATOM   14351 N N   . TYR D 1 479 ? -27.582 -29.721 -35.239  1.00 87.84  ? 472  TYR D N   1 
ATOM   14352 C CA  . TYR D 1 479 ? -27.452 -30.149 -33.819  1.00 93.37  ? 472  TYR D CA  1 
ATOM   14353 C C   . TYR D 1 479 ? -26.160 -30.954 -33.629  1.00 88.64  ? 472  TYR D C   1 
ATOM   14354 O O   . TYR D 1 479 ? -25.473 -30.710 -32.630  1.00 96.38  ? 472  TYR D O   1 
ATOM   14355 C CB  . TYR D 1 479 ? -28.713 -30.882 -33.338  1.00 97.36  ? 472  TYR D CB  1 
ATOM   14356 C CG  . TYR D 1 479 ? -29.909 -29.987 -33.097  1.00 96.66  ? 472  TYR D CG  1 
ATOM   14357 C CD1 . TYR D 1 479 ? -29.833 -28.892 -32.244  1.00 92.35  ? 472  TYR D CD1 1 
ATOM   14358 C CD2 . TYR D 1 479 ? -31.123 -30.224 -33.728  1.00 95.11  ? 472  TYR D CD2 1 
ATOM   14359 C CE1 . TYR D 1 479 ? -30.921 -28.057 -32.029  1.00 89.37  ? 472  TYR D CE1 1 
ATOM   14360 C CE2 . TYR D 1 479 ? -32.221 -29.401 -33.520  1.00 93.55  ? 472  TYR D CE2 1 
ATOM   14361 C CZ  . TYR D 1 479 ? -32.123 -28.313 -32.667  1.00 90.16  ? 472  TYR D CZ  1 
ATOM   14362 O OH  . TYR D 1 479 ? -33.206 -27.503 -32.462  1.00 83.53  ? 472  TYR D OH  1 
ATOM   14363 N N   . GLU D 1 480 ? -25.826 -31.856 -34.554  1.00 90.30  ? 473  GLU D N   1 
ATOM   14364 C CA  . GLU D 1 480 ? -24.565 -32.654 -34.522  1.00 91.81  ? 473  GLU D CA  1 
ATOM   14365 C C   . GLU D 1 480 ? -23.353 -31.700 -34.518  1.00 91.92  ? 473  GLU D C   1 
ATOM   14366 O O   . GLU D 1 480 ? -22.452 -31.892 -33.649  1.00 81.11  ? 473  GLU D O   1 
ATOM   14367 C CB  . GLU D 1 480 ? -24.546 -33.627 -35.706  1.00 95.33  ? 473  GLU D CB  1 
ATOM   14368 C CG  . GLU D 1 480 ? -23.537 -34.756 -35.567  1.00 99.86  ? 473  GLU D CG  1 
ATOM   14369 C CD  . GLU D 1 480 ? -23.412 -35.624 -36.810  1.00 102.40 ? 473  GLU D CD  1 
ATOM   14370 O OE1 . GLU D 1 480 ? -24.462 -35.906 -37.435  1.00 99.46  ? 473  GLU D OE1 1 
ATOM   14371 O OE2 . GLU D 1 480 ? -22.263 -35.992 -37.167  1.00 105.65 ? 473  GLU D OE2 1 
ATOM   14372 N N   . ILE D 1 481 ? -23.355 -30.708 -35.432  1.00 86.86  ? 474  ILE D N   1 
ATOM   14373 C CA  . ILE D 1 481 ? -22.314 -29.641 -35.613  1.00 82.40  ? 474  ILE D CA  1 
ATOM   14374 C C   . ILE D 1 481 ? -22.139 -28.852 -34.312  1.00 83.91  ? 474  ILE D C   1 
ATOM   14375 O O   . ILE D 1 481 ? -20.995 -28.486 -33.995  1.00 98.47  ? 474  ILE D O   1 
ATOM   14376 C CB  . ILE D 1 481 ? -22.673 -28.694 -36.782  1.00 79.71  ? 474  ILE D CB  1 
ATOM   14377 C CG1 . ILE D 1 481 ? -22.354 -29.332 -38.139  1.00 79.54  ? 474  ILE D CG1 1 
ATOM   14378 C CG2 . ILE D 1 481 ? -21.989 -27.338 -36.628  1.00 76.47  ? 474  ILE D CG2 1 
ATOM   14379 C CD1 . ILE D 1 481 ? -22.986 -28.636 -39.327  1.00 78.87  ? 474  ILE D CD1 1 
ATOM   14380 N N   . LEU D 1 482 ? -23.243 -28.588 -33.613  1.00 87.02  ? 475  LEU D N   1 
ATOM   14381 C CA  . LEU D 1 482 ? -23.323 -27.734 -32.395  1.00 84.68  ? 475  LEU D CA  1 
ATOM   14382 C C   . LEU D 1 482 ? -22.746 -28.475 -31.168  1.00 83.31  ? 475  LEU D C   1 
ATOM   14383 O O   . LEU D 1 482 ? -22.342 -27.782 -30.205  1.00 74.56  ? 475  LEU D O   1 
ATOM   14384 C CB  . LEU D 1 482 ? -24.801 -27.354 -32.221  1.00 82.03  ? 475  LEU D CB  1 
ATOM   14385 C CG  . LEU D 1 482 ? -25.138 -26.284 -31.184  1.00 78.19  ? 475  LEU D CG  1 
ATOM   14386 C CD1 . LEU D 1 482 ? -24.727 -24.897 -31.655  1.00 73.97  ? 475  LEU D CD1 1 
ATOM   14387 C CD2 . LEU D 1 482 ? -26.628 -26.320 -30.876  1.00 80.05  ? 475  LEU D CD2 1 
ATOM   14388 N N   . HIS D 1 483 ? -22.664 -29.817 -31.217  1.00 84.25  ? 476  HIS D N   1 
ATOM   14389 C CA  . HIS D 1 483 ? -22.302 -30.720 -30.085  1.00 84.43  ? 476  HIS D CA  1 
ATOM   14390 C C   . HIS D 1 483 ? -20.851 -31.207 -30.174  1.00 85.32  ? 476  HIS D C   1 
ATOM   14391 O O   . HIS D 1 483 ? -20.313 -31.576 -29.110  1.00 87.08  ? 476  HIS D O   1 
ATOM   14392 C CB  . HIS D 1 483 ? -23.256 -31.919 -30.028  1.00 82.07  ? 476  HIS D CB  1 
ATOM   14393 C CG  . HIS D 1 483 ? -24.499 -31.629 -29.263  1.00 84.89  ? 476  HIS D CG  1 
ATOM   14394 N ND1 . HIS D 1 483 ? -25.422 -30.695 -29.693  1.00 81.99  ? 476  HIS D ND1 1 
ATOM   14395 C CD2 . HIS D 1 483 ? -24.963 -32.123 -28.096  1.00 85.05  ? 476  HIS D CD2 1 
ATOM   14396 C CE1 . HIS D 1 483 ? -26.413 -30.633 -28.831  1.00 85.04  ? 476  HIS D CE1 1 
ATOM   14397 N NE2 . HIS D 1 483 ? -26.154 -31.501 -27.842  1.00 88.98  ? 476  HIS D NE2 1 
ATOM   14398 N N   . LEU D 1 484 ? -20.270 -31.260 -31.382  1.00 91.48  ? 477  LEU D N   1 
ATOM   14399 C CA  . LEU D 1 484 ? -18.848 -31.644 -31.620  1.00 96.78  ? 477  LEU D CA  1 
ATOM   14400 C C   . LEU D 1 484 ? -17.972 -30.873 -30.631  1.00 106.74 ? 477  LEU D C   1 
ATOM   14401 O O   . LEU D 1 484 ? -17.873 -29.649 -30.726  1.00 101.39 ? 477  LEU D O   1 
ATOM   14402 C CB  . LEU D 1 484 ? -18.465 -31.336 -33.074  1.00 93.18  ? 477  LEU D CB  1 
ATOM   14403 C CG  . LEU D 1 484 ? -19.002 -32.299 -34.139  1.00 90.07  ? 477  LEU D CG  1 
ATOM   14404 C CD1 . LEU D 1 484 ? -18.834 -31.716 -35.536  1.00 81.82  ? 477  LEU D CD1 1 
ATOM   14405 C CD2 . LEU D 1 484 ? -18.319 -33.657 -34.052  1.00 91.59  ? 477  LEU D CD2 1 
ATOM   14406 N N   . PRO D 1 485 ? -17.327 -31.550 -29.646  1.00 122.06 ? 478  PRO D N   1 
ATOM   14407 C CA  . PRO D 1 485 ? -16.775 -30.864 -28.472  1.00 124.27 ? 478  PRO D CA  1 
ATOM   14408 C C   . PRO D 1 485 ? -15.465 -30.070 -28.655  1.00 130.30 ? 478  PRO D C   1 
ATOM   14409 O O   . PRO D 1 485 ? -15.151 -29.331 -27.731  1.00 132.87 ? 478  PRO D O   1 
ATOM   14410 C CB  . PRO D 1 485 ? -16.542 -32.026 -27.488  1.00 120.62 ? 478  PRO D CB  1 
ATOM   14411 C CG  . PRO D 1 485 ? -16.212 -33.198 -28.387  1.00 122.85 ? 478  PRO D CG  1 
ATOM   14412 C CD  . PRO D 1 485 ? -17.102 -33.006 -29.600  1.00 123.38 ? 478  PRO D CD  1 
ATOM   14413 N N   . ASN D 1 486 ? -14.760 -30.197 -29.796  1.00 130.79 ? 479  ASN D N   1 
ATOM   14414 C CA  . ASN D 1 486 ? -13.385 -29.644 -29.999  1.00 125.78 ? 479  ASN D CA  1 
ATOM   14415 C C   . ASN D 1 486 ? -13.353 -28.434 -30.954  1.00 120.13 ? 479  ASN D C   1 
ATOM   14416 O O   . ASN D 1 486 ? -12.225 -27.975 -31.234  1.00 118.74 ? 479  ASN D O   1 
ATOM   14417 C CB  . ASN D 1 486 ? -12.399 -30.696 -30.521  1.00 121.94 ? 479  ASN D CB  1 
ATOM   14418 C CG  . ASN D 1 486 ? -12.278 -31.911 -29.625  1.00 124.02 ? 479  ASN D CG  1 
ATOM   14419 O OD1 . ASN D 1 486 ? -12.269 -31.794 -28.399  1.00 119.06 ? 479  ASN D OD1 1 
ATOM   14420 N ND2 . ASN D 1 486 ? -12.180 -33.082 -30.234  1.00 124.65 ? 479  ASN D ND2 1 
ATOM   14421 N N   . LEU D 1 487 ? -14.497 -27.921 -31.437  1.00 109.77 ? 480  LEU D N   1 
ATOM   14422 C CA  . LEU D 1 487 ? -14.567 -26.652 -32.228  1.00 97.79  ? 480  LEU D CA  1 
ATOM   14423 C C   . LEU D 1 487 ? -14.606 -25.452 -31.260  1.00 94.30  ? 480  LEU D C   1 
ATOM   14424 O O   . LEU D 1 487 ? -15.191 -25.596 -30.169  1.00 86.20  ? 480  LEU D O   1 
ATOM   14425 C CB  . LEU D 1 487 ? -15.806 -26.647 -33.138  1.00 89.23  ? 480  LEU D CB  1 
ATOM   14426 C CG  . LEU D 1 487 ? -15.960 -27.805 -34.128  1.00 83.93  ? 480  LEU D CG  1 
ATOM   14427 C CD1 . LEU D 1 487 ? -17.339 -27.780 -34.773  1.00 78.98  ? 480  LEU D CD1 1 
ATOM   14428 C CD2 . LEU D 1 487 ? -14.885 -27.774 -35.203  1.00 88.04  ? 480  LEU D CD2 1 
ATOM   14429 N N   . ASN D 1 488 ? -13.985 -24.323 -31.635  1.00 92.28  ? 481  ASN D N   1 
ATOM   14430 C CA  . ASN D 1 488 ? -14.149 -22.983 -30.994  1.00 87.82  ? 481  ASN D CA  1 
ATOM   14431 C C   . ASN D 1 488 ? -15.465 -22.354 -31.485  1.00 77.25  ? 481  ASN D C   1 
ATOM   14432 O O   . ASN D 1 488 ? -16.075 -22.939 -32.396  1.00 64.74  ? 481  ASN D O   1 
ATOM   14433 C CB  . ASN D 1 488 ? -12.944 -22.072 -31.265  1.00 87.04  ? 481  ASN D CB  1 
ATOM   14434 C CG  . ASN D 1 488 ? -12.809 -21.671 -32.722  1.00 89.29  ? 481  ASN D CG  1 
ATOM   14435 O OD1 . ASN D 1 488 ? -13.638 -20.936 -33.254  1.00 90.19  ? 481  ASN D OD1 1 
ATOM   14436 N ND2 . ASN D 1 488 ? -11.754 -22.126 -33.374  1.00 88.69  ? 481  ASN D ND2 1 
ATOM   14437 N N   . GLU D 1 489 ? -15.871 -21.199 -30.934  1.00 74.60  ? 482  GLU D N   1 
ATOM   14438 C CA  . GLU D 1 489 ? -17.220 -20.610 -31.168  1.00 82.64  ? 482  GLU D CA  1 
ATOM   14439 C C   . GLU D 1 489 ? -17.266 -19.871 -32.514  1.00 83.47  ? 482  GLU D C   1 
ATOM   14440 O O   . GLU D 1 489 ? -18.362 -19.834 -33.111  1.00 84.83  ? 482  GLU D O   1 
ATOM   14441 C CB  . GLU D 1 489 ? -17.685 -19.734 -29.996  1.00 87.53  ? 482  GLU D CB  1 
ATOM   14442 C CG  . GLU D 1 489 ? -18.665 -20.448 -29.059  1.00 92.57  ? 482  GLU D CG  1 
ATOM   14443 C CD  . GLU D 1 489 ? -19.884 -21.103 -29.716  1.00 94.34  ? 482  GLU D CD  1 
ATOM   14444 O OE1 . GLU D 1 489 ? -20.704 -20.372 -30.319  1.00 87.84  ? 482  GLU D OE1 1 
ATOM   14445 O OE2 . GLU D 1 489 ? -20.019 -22.355 -29.634  1.00 89.63  ? 482  GLU D OE2 1 
ATOM   14446 N N   . GLU D 1 490 ? -16.144 -19.337 -33.006  1.00 83.97  ? 483  GLU D N   1 
ATOM   14447 C CA  . GLU D 1 490 ? -16.070 -18.732 -34.371  1.00 83.88  ? 483  GLU D CA  1 
ATOM   14448 C C   . GLU D 1 490 ? -16.300 -19.814 -35.447  1.00 82.01  ? 483  GLU D C   1 
ATOM   14449 O O   . GLU D 1 490 ? -16.990 -19.512 -36.449  1.00 66.88  ? 483  GLU D O   1 
ATOM   14450 C CB  . GLU D 1 490 ? -14.734 -18.012 -34.583  1.00 78.69  ? 483  GLU D CB  1 
ATOM   14451 C CG  . GLU D 1 490 ? -14.743 -17.071 -35.781  1.00 77.36  ? 483  GLU D CG  1 
ATOM   14452 C CD  . GLU D 1 490 ? -13.397 -16.837 -36.454  1.00 76.34  ? 483  GLU D CD  1 
ATOM   14453 O OE1 . GLU D 1 490 ? -12.568 -17.773 -36.468  1.00 79.09  ? 483  GLU D OE1 1 
ATOM   14454 O OE2 . GLU D 1 490 ? -13.180 -15.722 -36.978  1.00 65.29  ? 483  GLU D OE2 1 
ATOM   14455 N N   . GLN D 1 491 ? -15.750 -21.023 -35.241  1.00 88.77  ? 484  GLN D N   1 
ATOM   14456 C CA  . GLN D 1 491 ? -15.757 -22.170 -36.202  1.00 89.03  ? 484  GLN D CA  1 
ATOM   14457 C C   . GLN D 1 491 ? -17.155 -22.798 -36.294  1.00 86.69  ? 484  GLN D C   1 
ATOM   14458 O O   . GLN D 1 491 ? -17.624 -23.022 -37.426  1.00 84.57  ? 484  GLN D O   1 
ATOM   14459 C CB  . GLN D 1 491 ? -14.769 -23.262 -35.776  1.00 91.87  ? 484  GLN D CB  1 
ATOM   14460 C CG  . GLN D 1 491 ? -13.319 -23.005 -36.173  1.00 91.90  ? 484  GLN D CG  1 
ATOM   14461 C CD  . GLN D 1 491 ? -12.434 -24.197 -35.893  1.00 90.82  ? 484  GLN D CD  1 
ATOM   14462 O OE1 . GLN D 1 491 ? -11.645 -24.617 -36.734  1.00 87.18  ? 484  GLN D OE1 1 
ATOM   14463 N NE2 . GLN D 1 491 ? -12.576 -24.776 -34.709  1.00 90.82  ? 484  GLN D NE2 1 
ATOM   14464 N N   . ARG D 1 492 ? -17.748 -23.131 -35.142  1.00 88.87  ? 485  ARG D N   1 
ATOM   14465 C CA  . ARG D 1 492 ? -19.139 -23.651 -34.995  1.00 90.03  ? 485  ARG D CA  1 
ATOM   14466 C C   . ARG D 1 492 ? -20.108 -22.657 -35.652  1.00 85.14  ? 485  ARG D C   1 
ATOM   14467 O O   . ARG D 1 492 ? -20.981 -23.104 -36.431  1.00 79.59  ? 485  ARG D O   1 
ATOM   14468 C CB  . ARG D 1 492 ? -19.454 -23.847 -33.505  1.00 95.35  ? 485  ARG D CB  1 
ATOM   14469 C CG  . ARG D 1 492 ? -20.729 -24.624 -33.199  1.00 95.82  ? 485  ARG D CG  1 
ATOM   14470 C CD  . ARG D 1 492 ? -21.008 -24.727 -31.704  1.00 97.60  ? 485  ARG D CD  1 
ATOM   14471 N NE  . ARG D 1 492 ? -19.835 -25.037 -30.892  1.00 97.60  ? 485  ARG D NE  1 
ATOM   14472 C CZ  . ARG D 1 492 ? -19.209 -26.217 -30.856  1.00 101.50 ? 485  ARG D CZ  1 
ATOM   14473 N NH1 . ARG D 1 492 ? -19.623 -27.236 -31.596  1.00 104.91 ? 485  ARG D NH1 1 
ATOM   14474 N NH2 . ARG D 1 492 ? -18.155 -26.376 -30.073  1.00 97.96  ? 485  ARG D NH2 1 
ATOM   14475 N N   . ASN D 1 493 ? -19.915 -21.362 -35.364  1.00 83.27  ? 486  ASN D N   1 
ATOM   14476 C CA  . ASN D 1 493 ? -20.712 -20.210 -35.871  1.00 84.93  ? 486  ASN D CA  1 
ATOM   14477 C C   . ASN D 1 493 ? -20.549 -20.097 -37.403  1.00 88.35  ? 486  ASN D C   1 
ATOM   14478 O O   . ASN D 1 493 ? -21.565 -19.881 -38.079  1.00 92.39  ? 486  ASN D O   1 
ATOM   14479 C CB  . ASN D 1 493 ? -20.342 -18.949 -35.079  1.00 84.73  ? 486  ASN D CB  1 
ATOM   14480 C CG  . ASN D 1 493 ? -21.251 -17.766 -35.331  1.00 91.29  ? 486  ASN D CG  1 
ATOM   14481 O OD1 . ASN D 1 493 ? -22.429 -17.772 -34.968  1.00 82.10  ? 486  ASN D OD1 1 
ATOM   14482 N ND2 . ASN D 1 493 ? -20.693 -16.727 -35.927  1.00 98.01  ? 486  ASN D ND2 1 
ATOM   14483 N N   . ALA D 1 494 ? -19.337 -20.282 -37.943  1.00 93.42  ? 487  ALA D N   1 
ATOM   14484 C CA  . ALA D 1 494 ? -19.038 -20.258 -39.399  1.00 88.76  ? 487  ALA D CA  1 
ATOM   14485 C C   . ALA D 1 494 ? -19.740 -21.417 -40.133  1.00 91.59  ? 487  ALA D C   1 
ATOM   14486 O O   . ALA D 1 494 ? -20.181 -21.189 -41.278  1.00 90.05  ? 487  ALA D O   1 
ATOM   14487 C CB  . ALA D 1 494 ? -17.545 -20.292 -39.622  1.00 85.23  ? 487  ALA D CB  1 
ATOM   14488 N N   . PHE D 1 495 ? -19.834 -22.610 -39.519  1.00 93.37  ? 488  PHE D N   1 
ATOM   14489 C CA  . PHE D 1 495 ? -20.430 -23.849 -40.108  1.00 91.65  ? 488  PHE D CA  1 
ATOM   14490 C C   . PHE D 1 495 ? -21.966 -23.798 -40.067  1.00 91.24  ? 488  PHE D C   1 
ATOM   14491 O O   . PHE D 1 495 ? -22.615 -24.346 -40.994  1.00 87.71  ? 488  PHE D O   1 
ATOM   14492 C CB  . PHE D 1 495 ? -19.957 -25.112 -39.374  1.00 92.03  ? 488  PHE D CB  1 
ATOM   14493 C CG  . PHE D 1 495 ? -18.625 -25.663 -39.822  1.00 92.45  ? 488  PHE D CG  1 
ATOM   14494 C CD1 . PHE D 1 495 ? -18.393 -25.957 -41.159  1.00 87.58  ? 488  PHE D CD1 1 
ATOM   14495 C CD2 . PHE D 1 495 ? -17.611 -25.906 -38.904  1.00 86.44  ? 488  PHE D CD2 1 
ATOM   14496 C CE1 . PHE D 1 495 ? -17.174 -26.472 -41.569  1.00 85.47  ? 488  PHE D CE1 1 
ATOM   14497 C CE2 . PHE D 1 495 ? -16.392 -26.419 -39.318  1.00 83.75  ? 488  PHE D CE2 1 
ATOM   14498 C CZ  . PHE D 1 495 ? -16.176 -26.699 -40.649  1.00 86.81  ? 488  PHE D CZ  1 
ATOM   14499 N N   . ILE D 1 496 ? -22.532 -23.192 -39.015  1.00 86.60  ? 489  ILE D N   1 
ATOM   14500 C CA  . ILE D 1 496 ? -24.005 -23.027 -38.834  1.00 80.84  ? 489  ILE D CA  1 
ATOM   14501 C C   . ILE D 1 496 ? -24.523 -21.883 -39.731  1.00 83.69  ? 489  ILE D C   1 
ATOM   14502 O O   . ILE D 1 496 ? -25.655 -22.034 -40.230  1.00 83.21  ? 489  ILE D O   1 
ATOM   14503 C CB  . ILE D 1 496 ? -24.361 -22.866 -37.340  1.00 74.23  ? 489  ILE D CB  1 
ATOM   14504 C CG1 . ILE D 1 496 ? -24.113 -24.174 -36.579  1.00 72.97  ? 489  ILE D CG1 1 
ATOM   14505 C CG2 . ILE D 1 496 ? -25.797 -22.394 -37.169  1.00 78.58  ? 489  ILE D CG2 1 
ATOM   14506 C CD1 . ILE D 1 496 ? -24.261 -24.073 -35.073  1.00 70.52  ? 489  ILE D CD1 1 
ATOM   14507 N N   . GLN D 1 497 ? -23.745 -20.806 -39.961  1.00 90.66  ? 490  GLN D N   1 
ATOM   14508 C CA  . GLN D 1 497 ? -24.077 -19.705 -40.926  1.00 91.43  ? 490  GLN D CA  1 
ATOM   14509 C C   . GLN D 1 497 ? -24.092 -20.261 -42.360  1.00 92.83  ? 490  GLN D C   1 
ATOM   14510 O O   . GLN D 1 497 ? -25.000 -19.881 -43.116  1.00 102.47 ? 490  GLN D O   1 
ATOM   14511 C CB  . GLN D 1 497 ? -23.092 -18.524 -40.909  1.00 93.64  ? 490  GLN D CB  1 
ATOM   14512 C CG  . GLN D 1 497 ? -23.022 -17.698 -39.623  1.00 94.45  ? 490  GLN D CG  1 
ATOM   14513 C CD  . GLN D 1 497 ? -24.326 -17.496 -38.888  1.00 93.13  ? 490  GLN D CD  1 
ATOM   14514 O OE1 . GLN D 1 497 ? -25.400 -17.348 -39.473  1.00 89.39  ? 490  GLN D OE1 1 
ATOM   14515 N NE2 . GLN D 1 497 ? -24.233 -17.482 -37.570  1.00 89.42  ? 490  GLN D NE2 1 
ATOM   14516 N N   . SER D 1 498 ? -23.109 -21.102 -42.717  1.00 95.55  ? 491  SER D N   1 
ATOM   14517 C CA  . SER D 1 498 ? -23.030 -21.882 -43.987  1.00 98.16  ? 491  SER D CA  1 
ATOM   14518 C C   . SER D 1 498 ? -24.297 -22.733 -44.176  1.00 105.29 ? 491  SER D C   1 
ATOM   14519 O O   . SER D 1 498 ? -24.874 -22.690 -45.274  1.00 117.66 ? 491  SER D O   1 
ATOM   14520 C CB  . SER D 1 498 ? -21.788 -22.762 -44.032  1.00 94.32  ? 491  SER D CB  1 
ATOM   14521 O OG  . SER D 1 498 ? -20.643 -22.038 -44.453  1.00 85.27  ? 491  SER D OG  1 
ATOM   14522 N N   . LEU D 1 499 ? -24.704 -23.471 -43.138  1.00 114.35 ? 492  LEU D N   1 
ATOM   14523 C CA  . LEU D 1 499 ? -25.812 -24.466 -43.163  1.00 119.57 ? 492  LEU D CA  1 
ATOM   14524 C C   . LEU D 1 499 ? -27.178 -23.787 -43.384  1.00 126.72 ? 492  LEU D C   1 
ATOM   14525 O O   . LEU D 1 499 ? -27.945 -24.310 -44.215  1.00 140.14 ? 492  LEU D O   1 
ATOM   14526 C CB  . LEU D 1 499 ? -25.788 -25.241 -41.842  1.00 126.87 ? 492  LEU D CB  1 
ATOM   14527 C CG  . LEU D 1 499 ? -26.864 -26.313 -41.696  1.00 133.89 ? 492  LEU D CG  1 
ATOM   14528 C CD1 . LEU D 1 499 ? -26.517 -27.530 -42.537  1.00 139.59 ? 492  LEU D CD1 1 
ATOM   14529 C CD2 . LEU D 1 499 ? -27.050 -26.693 -40.239  1.00 135.44 ? 492  LEU D CD2 1 
ATOM   14530 N N   . LYS D 1 500 ? -27.498 -22.703 -42.655  1.00 126.97 ? 493  LYS D N   1 
ATOM   14531 C CA  . LYS D 1 500 ? -28.802 -21.973 -42.749  1.00 117.87 ? 493  LYS D CA  1 
ATOM   14532 C C   . LYS D 1 500 ? -28.825 -21.131 -44.037  1.00 117.58 ? 493  LYS D C   1 
ATOM   14533 O O   . LYS D 1 500 ? -29.894 -21.045 -44.683  1.00 109.47 ? 493  LYS D O   1 
ATOM   14534 C CB  . LYS D 1 500 ? -29.046 -21.097 -41.512  1.00 112.10 ? 493  LYS D CB  1 
ATOM   14535 C CG  . LYS D 1 500 ? -29.338 -21.846 -40.211  1.00 112.79 ? 493  LYS D CG  1 
ATOM   14536 C CD  . LYS D 1 500 ? -29.400 -20.963 -38.967  1.00 107.03 ? 493  LYS D CD  1 
ATOM   14537 C CE  . LYS D 1 500 ? -28.304 -19.912 -38.931  1.00 108.89 ? 493  LYS D CE  1 
ATOM   14538 N NZ  . LYS D 1 500 ? -28.053 -19.377 -37.572  1.00 102.19 ? 493  LYS D NZ  1 
ATOM   14539 N N   . ASP D 1 501 ? -27.679 -20.552 -44.402  1.00 122.74 ? 494  ASP D N   1 
ATOM   14540 C CA  . ASP D 1 501 ? -27.468 -19.755 -45.643  1.00 127.81 ? 494  ASP D CA  1 
ATOM   14541 C C   . ASP D 1 501 ? -27.649 -20.635 -46.898  1.00 131.36 ? 494  ASP D C   1 
ATOM   14542 O O   . ASP D 1 501 ? -28.118 -20.098 -47.923  1.00 123.60 ? 494  ASP D O   1 
ATOM   14543 C CB  . ASP D 1 501 ? -26.088 -19.091 -45.599  1.00 126.07 ? 494  ASP D CB  1 
ATOM   14544 C CG  . ASP D 1 501 ? -25.741 -18.284 -46.832  1.00 123.56 ? 494  ASP D CG  1 
ATOM   14545 O OD1 . ASP D 1 501 ? -26.192 -17.131 -46.918  1.00 133.05 ? 494  ASP D OD1 1 
ATOM   14546 O OD2 . ASP D 1 501 ? -25.028 -18.824 -47.692  1.00 114.89 ? 494  ASP D OD2 1 
ATOM   14547 N N   . ASP D 1 502 ? -27.297 -21.929 -46.828  1.00 134.99 ? 495  ASP D N   1 
ATOM   14548 C CA  . ASP D 1 502 ? -27.401 -22.905 -47.953  1.00 128.34 ? 495  ASP D CA  1 
ATOM   14549 C C   . ASP D 1 502 ? -27.666 -24.324 -47.431  1.00 135.78 ? 495  ASP D C   1 
ATOM   14550 O O   . ASP D 1 502 ? -26.733 -25.131 -47.344  1.00 129.02 ? 495  ASP D O   1 
ATOM   14551 C CB  . ASP D 1 502 ? -26.127 -22.860 -48.798  1.00 122.90 ? 495  ASP D CB  1 
ATOM   14552 C CG  . ASP D 1 502 ? -26.181 -23.721 -50.045  1.00 128.00 ? 495  ASP D CG  1 
ATOM   14553 O OD1 . ASP D 1 502 ? -27.214 -24.394 -50.261  1.00 146.82 ? 495  ASP D OD1 1 
ATOM   14554 O OD2 . ASP D 1 502 ? -25.193 -23.702 -50.795  1.00 129.96 ? 495  ASP D OD2 1 
ATOM   14555 N N   . PRO D 1 503 ? -28.939 -24.696 -47.119  1.00 138.46 ? 496  PRO D N   1 
ATOM   14556 C CA  . PRO D 1 503 ? -29.247 -25.987 -46.485  1.00 134.55 ? 496  PRO D CA  1 
ATOM   14557 C C   . PRO D 1 503 ? -28.903 -27.231 -47.326  1.00 128.12 ? 496  PRO D C   1 
ATOM   14558 O O   . PRO D 1 503 ? -28.830 -28.310 -46.755  1.00 118.69 ? 496  PRO D O   1 
ATOM   14559 C CB  . PRO D 1 503 ? -30.768 -25.937 -46.224  1.00 129.31 ? 496  PRO D CB  1 
ATOM   14560 C CG  . PRO D 1 503 ? -31.120 -24.461 -46.305  1.00 124.23 ? 496  PRO D CG  1 
ATOM   14561 C CD  . PRO D 1 503 ? -30.154 -23.886 -47.323  1.00 128.05 ? 496  PRO D CD  1 
ATOM   14562 N N   . SER D 1 504 ? -28.663 -27.049 -48.631  1.00 126.60 ? 497  SER D N   1 
ATOM   14563 C CA  . SER D 1 504 ? -28.426 -28.130 -49.628  1.00 125.37 ? 497  SER D CA  1 
ATOM   14564 C C   . SER D 1 504 ? -26.980 -28.654 -49.570  1.00 125.50 ? 497  SER D C   1 
ATOM   14565 O O   . SER D 1 504 ? -26.646 -29.525 -50.397  1.00 122.86 ? 497  SER D O   1 
ATOM   14566 C CB  . SER D 1 504 ? -28.782 -27.652 -51.016  1.00 118.23 ? 497  SER D CB  1 
ATOM   14567 O OG  . SER D 1 504 ? -27.858 -26.672 -51.466  1.00 121.90 ? 497  SER D OG  1 
ATOM   14568 N N   . GLN D 1 505 ? -26.150 -28.170 -48.638  1.00 128.30 ? 498  GLN D N   1 
ATOM   14569 C CA  . GLN D 1 505 ? -24.736 -28.612 -48.483  1.00 129.14 ? 498  GLN D CA  1 
ATOM   14570 C C   . GLN D 1 505 ? -24.493 -29.204 -47.091  1.00 127.68 ? 498  GLN D C   1 
ATOM   14571 O O   . GLN D 1 505 ? -23.329 -29.205 -46.656  1.00 128.30 ? 498  GLN D O   1 
ATOM   14572 C CB  . GLN D 1 505 ? -23.799 -27.431 -48.715  1.00 131.12 ? 498  GLN D CB  1 
ATOM   14573 C CG  . GLN D 1 505 ? -24.022 -26.766 -50.060  1.00 128.57 ? 498  GLN D CG  1 
ATOM   14574 C CD  . GLN D 1 505 ? -22.725 -26.302 -50.670  1.00 129.41 ? 498  GLN D CD  1 
ATOM   14575 O OE1 . GLN D 1 505 ? -21.745 -27.039 -50.729  1.00 124.28 ? 498  GLN D OE1 1 
ATOM   14576 N NE2 . GLN D 1 505 ? -22.713 -25.062 -51.129  1.00 133.21 ? 498  GLN D NE2 1 
ATOM   14577 N N   . SER D 1 506 ? -25.539 -29.721 -46.441  1.00 125.60 ? 499  SER D N   1 
ATOM   14578 C CA  . SER D 1 506 ? -25.515 -30.198 -45.032  1.00 118.69 ? 499  SER D CA  1 
ATOM   14579 C C   . SER D 1 506 ? -24.612 -31.437 -44.887  1.00 114.83 ? 499  SER D C   1 
ATOM   14580 O O   . SER D 1 506 ? -23.882 -31.511 -43.880  1.00 112.35 ? 499  SER D O   1 
ATOM   14581 C CB  . SER D 1 506 ? -26.919 -30.443 -44.525  1.00 118.04 ? 499  SER D CB  1 
ATOM   14582 O OG  . SER D 1 506 ? -27.562 -31.473 -45.257  1.00 118.30 ? 499  SER D OG  1 
ATOM   14583 N N   . ALA D 1 507 ? -24.643 -32.359 -45.856  1.00 115.07 ? 500  ALA D N   1 
ATOM   14584 C CA  . ALA D 1 507 ? -23.795 -33.577 -45.910  1.00 118.02 ? 500  ALA D CA  1 
ATOM   14585 C C   . ALA D 1 507 ? -22.308 -33.185 -45.960  1.00 127.67 ? 500  ALA D C   1 
ATOM   14586 O O   . ALA D 1 507 ? -21.497 -33.757 -45.181  1.00 118.54 ? 500  ALA D O   1 
ATOM   14587 C CB  . ALA D 1 507 ? -24.190 -34.407 -47.110  1.00 113.73 ? 500  ALA D CB  1 
ATOM   14588 N N   . ASN D 1 508 ? -21.978 -32.224 -46.833  1.00 139.97 ? 501  ASN D N   1 
ATOM   14589 C CA  . ASN D 1 508 ? -20.601 -31.734 -47.129  1.00 135.51 ? 501  ASN D CA  1 
ATOM   14590 C C   . ASN D 1 508 ? -20.026 -31.004 -45.907  1.00 130.09 ? 501  ASN D C   1 
ATOM   14591 O O   . ASN D 1 508 ? -18.890 -31.346 -45.512  1.00 114.06 ? 501  ASN D O   1 
ATOM   14592 C CB  . ASN D 1 508 ? -20.587 -30.816 -48.357  1.00 133.33 ? 501  ASN D CB  1 
ATOM   14593 C CG  . ASN D 1 508 ? -21.283 -31.431 -49.552  1.00 126.00 ? 501  ASN D CG  1 
ATOM   14594 O OD1 . ASN D 1 508 ? -21.001 -32.570 -49.910  1.00 123.10 ? 501  ASN D OD1 1 
ATOM   14595 N ND2 . ASN D 1 508 ? -22.208 -30.705 -50.158  1.00 117.07 ? 501  ASN D ND2 1 
ATOM   14596 N N   . LEU D 1 509 ? -20.785 -30.039 -45.361  1.00 134.07 ? 502  LEU D N   1 
ATOM   14597 C CA  . LEU D 1 509 ? -20.425 -29.172 -44.196  1.00 126.57 ? 502  LEU D CA  1 
ATOM   14598 C C   . LEU D 1 509 ? -20.265 -30.023 -42.925  1.00 124.22 ? 502  LEU D C   1 
ATOM   14599 O O   . LEU D 1 509 ? -19.370 -29.702 -42.107  1.00 111.85 ? 502  LEU D O   1 
ATOM   14600 C CB  . LEU D 1 509 ? -21.508 -28.103 -43.988  1.00 120.77 ? 502  LEU D CB  1 
ATOM   14601 C CG  . LEU D 1 509 ? -21.624 -27.019 -45.062  1.00 112.56 ? 502  LEU D CG  1 
ATOM   14602 C CD1 . LEU D 1 509 ? -22.884 -26.190 -44.845  1.00 110.59 ? 502  LEU D CD1 1 
ATOM   14603 C CD2 . LEU D 1 509 ? -20.391 -26.125 -45.089  1.00 106.75 ? 502  LEU D CD2 1 
ATOM   14604 N N   . LEU D 1 510 ? -21.108 -31.050 -42.755  1.00 125.94 ? 503  LEU D N   1 
ATOM   14605 C CA  . LEU D 1 510 ? -21.050 -32.003 -41.612  1.00 131.70 ? 503  LEU D CA  1 
ATOM   14606 C C   . LEU D 1 510 ? -19.713 -32.760 -41.653  1.00 136.23 ? 503  LEU D C   1 
ATOM   14607 O O   . LEU D 1 510 ? -18.992 -32.742 -40.624  1.00 143.43 ? 503  LEU D O   1 
ATOM   14608 C CB  . LEU D 1 510 ? -22.253 -32.952 -41.686  1.00 129.51 ? 503  LEU D CB  1 
ATOM   14609 C CG  . LEU D 1 510 ? -22.419 -33.929 -40.520  1.00 124.76 ? 503  LEU D CG  1 
ATOM   14610 C CD1 . LEU D 1 510 ? -22.134 -33.250 -39.185  1.00 118.08 ? 503  LEU D CD1 1 
ATOM   14611 C CD2 . LEU D 1 510 ? -23.814 -34.542 -40.527  1.00 118.96 ? 503  LEU D CD2 1 
ATOM   14612 N N   . ALA D 1 511 ? -19.388 -33.364 -42.805  1.00 134.76 ? 504  ALA D N   1 
ATOM   14613 C CA  . ALA D 1 511 ? -18.124 -34.091 -43.085  1.00 125.28 ? 504  ALA D CA  1 
ATOM   14614 C C   . ALA D 1 511 ? -16.914 -33.224 -42.687  1.00 125.13 ? 504  ALA D C   1 
ATOM   14615 O O   . ALA D 1 511 ? -16.022 -33.722 -41.944  1.00 121.69 ? 504  ALA D O   1 
ATOM   14616 C CB  . ALA D 1 511 ? -18.084 -34.485 -44.545  1.00 115.73 ? 504  ALA D CB  1 
ATOM   14617 N N   . GLU D 1 512 ? -16.905 -31.965 -43.144  1.00 121.69 ? 505  GLU D N   1 
ATOM   14618 C CA  . GLU D 1 512 ? -15.818 -30.962 -42.952  1.00 119.35 ? 505  GLU D CA  1 
ATOM   14619 C C   . GLU D 1 512 ? -15.608 -30.686 -41.457  1.00 117.26 ? 505  GLU D C   1 
ATOM   14620 O O   . GLU D 1 512 ? -14.436 -30.659 -41.018  1.00 114.60 ? 505  GLU D O   1 
ATOM   14621 C CB  . GLU D 1 512 ? -16.179 -29.667 -43.690  1.00 121.51 ? 505  GLU D CB  1 
ATOM   14622 C CG  . GLU D 1 512 ? -15.046 -28.656 -43.792  1.00 121.47 ? 505  GLU D CG  1 
ATOM   14623 C CD  . GLU D 1 512 ? -15.337 -27.439 -44.662  1.00 117.10 ? 505  GLU D CD  1 
ATOM   14624 O OE1 . GLU D 1 512 ? -14.396 -26.663 -44.910  1.00 109.05 ? 505  GLU D OE1 1 
ATOM   14625 O OE2 . GLU D 1 512 ? -16.501 -27.264 -45.096  1.00 109.08 ? 505  GLU D OE2 1 
ATOM   14626 N N   . ALA D 1 513 ? -16.702 -30.475 -40.719  1.00 115.36 ? 506  ALA D N   1 
ATOM   14627 C CA  . ALA D 1 513 ? -16.715 -30.102 -39.285  1.00 113.02 ? 506  ALA D CA  1 
ATOM   14628 C C   . ALA D 1 513 ? -16.214 -31.272 -38.428  1.00 112.93 ? 506  ALA D C   1 
ATOM   14629 O O   . ALA D 1 513 ? -15.498 -31.008 -37.430  1.00 102.65 ? 506  ALA D O   1 
ATOM   14630 C CB  . ALA D 1 513 ? -18.107 -29.673 -38.888  1.00 116.41 ? 506  ALA D CB  1 
ATOM   14631 N N   . LYS D 1 514 ? -16.585 -32.505 -38.799  1.00 117.42 ? 507  LYS D N   1 
ATOM   14632 C CA  . LYS D 1 514 ? -16.160 -33.765 -38.127  1.00 122.14 ? 507  LYS D CA  1 
ATOM   14633 C C   . LYS D 1 514 ? -14.632 -33.890 -38.221  1.00 123.13 ? 507  LYS D C   1 
ATOM   14634 O O   . LYS D 1 514 ? -14.012 -34.253 -37.199  1.00 123.06 ? 507  LYS D O   1 
ATOM   14635 C CB  . LYS D 1 514 ? -16.882 -34.972 -38.741  1.00 127.03 ? 507  LYS D CB  1 
ATOM   14636 C CG  . LYS D 1 514 ? -18.372 -35.072 -38.425  1.00 127.71 ? 507  LYS D CG  1 
ATOM   14637 C CD  . LYS D 1 514 ? -19.174 -35.860 -39.450  1.00 131.60 ? 507  LYS D CD  1 
ATOM   14638 C CE  . LYS D 1 514 ? -18.748 -37.307 -39.577  1.00 131.02 ? 507  LYS D CE  1 
ATOM   14639 N NZ  . LYS D 1 514 ? -19.019 -38.050 -38.324  1.00 133.11 ? 507  LYS D NZ  1 
ATOM   14640 N N   . LYS D 1 515 ? -14.056 -33.565 -39.387  1.00 123.28 ? 508  LYS D N   1 
ATOM   14641 C CA  . LYS D 1 515 ? -12.587 -33.568 -39.664  1.00 124.00 ? 508  LYS D CA  1 
ATOM   14642 C C   . LYS D 1 515 ? -11.822 -32.630 -38.714  1.00 127.40 ? 508  LYS D C   1 
ATOM   14643 O O   . LYS D 1 515 ? -10.809 -33.083 -38.135  1.00 137.73 ? 508  LYS D O   1 
ATOM   14644 C CB  . LYS D 1 515 ? -12.304 -33.142 -41.108  1.00 114.73 ? 508  LYS D CB  1 
ATOM   14645 C CG  . LYS D 1 515 ? -12.041 -34.278 -42.083  1.00 110.94 ? 508  LYS D CG  1 
ATOM   14646 C CD  . LYS D 1 515 ? -11.447 -33.797 -43.382  1.00 110.61 ? 508  LYS D CD  1 
ATOM   14647 C CE  . LYS D 1 515 ? -12.324 -32.774 -44.074  1.00 110.37 ? 508  LYS D CE  1 
ATOM   14648 N NZ  . LYS D 1 515 ? -11.711 -32.299 -45.335  1.00 106.26 ? 508  LYS D NZ  1 
ATOM   14649 N N   . LEU D 1 516 ? -12.255 -31.368 -38.592  1.00 125.45 ? 509  LEU D N   1 
ATOM   14650 C CA  . LEU D 1 516 ? -11.560 -30.302 -37.810  1.00 113.50 ? 509  LEU D CA  1 
ATOM   14651 C C   . LEU D 1 516 ? -11.762 -30.520 -36.305  1.00 108.90 ? 509  LEU D C   1 
ATOM   14652 O O   . LEU D 1 516 ? -10.867 -30.106 -35.536  1.00 96.88  ? 509  LEU D O   1 
ATOM   14653 C CB  . LEU D 1 516 ? -12.076 -28.929 -38.251  1.00 111.28 ? 509  LEU D CB  1 
ATOM   14654 C CG  . LEU D 1 516 ? -11.670 -28.519 -39.666  1.00 112.25 ? 509  LEU D CG  1 
ATOM   14655 C CD1 . LEU D 1 516 ? -12.423 -27.273 -40.115  1.00 109.93 ? 509  LEU D CD1 1 
ATOM   14656 C CD2 . LEU D 1 516 ? -10.161 -28.312 -39.759  1.00 107.37 ? 509  LEU D CD2 1 
ATOM   14657 N N   . ASN D 1 517 ? -12.875 -31.157 -35.910  1.00 113.16 ? 510  ASN D N   1 
ATOM   14658 C CA  . ASN D 1 517 ? -13.166 -31.579 -34.508  1.00 116.67 ? 510  ASN D CA  1 
ATOM   14659 C C   . ASN D 1 517 ? -12.171 -32.671 -34.078  1.00 122.42 ? 510  ASN D C   1 
ATOM   14660 O O   . ASN D 1 517 ? -11.564 -32.509 -32.994  1.00 132.19 ? 510  ASN D O   1 
ATOM   14661 C CB  . ASN D 1 517 ? -14.620 -32.033 -34.333  1.00 110.73 ? 510  ASN D CB  1 
ATOM   14662 C CG  . ASN D 1 517 ? -14.892 -32.633 -32.969  1.00 107.78 ? 510  ASN D CG  1 
ATOM   14663 O OD1 . ASN D 1 517 ? -14.990 -31.925 -31.966  1.00 97.22  ? 510  ASN D OD1 1 
ATOM   14664 N ND2 . ASN D 1 517 ? -15.013 -33.949 -32.925  1.00 112.14 ? 510  ASN D ND2 1 
ATOM   14665 N N   . ASP D 1 518 ? -12.004 -33.730 -34.888  1.00 122.18 ? 511  ASP D N   1 
ATOM   14666 C CA  . ASP D 1 518 ? -10.992 -34.810 -34.683  1.00 114.49 ? 511  ASP D CA  1 
ATOM   14667 C C   . ASP D 1 518 ? -9.596  -34.190 -34.507  1.00 113.49 ? 511  ASP D C   1 
ATOM   14668 O O   . ASP D 1 518 ? -8.842  -34.689 -33.642  1.00 112.91 ? 511  ASP D O   1 
ATOM   14669 C CB  . ASP D 1 518 ? -10.928 -35.803 -35.852  1.00 106.49 ? 511  ASP D CB  1 
ATOM   14670 C CG  . ASP D 1 518 ? -12.226 -36.522 -36.176  1.00 101.94 ? 511  ASP D CG  1 
ATOM   14671 O OD1 . ASP D 1 518 ? -13.143 -36.504 -35.334  1.00 99.63  ? 511  ASP D OD1 1 
ATOM   14672 O OD2 . ASP D 1 518 ? -12.309 -37.086 -37.278  1.00 98.52  ? 511  ASP D OD2 1 
ATOM   14673 N N   . ALA D 1 519 ? -9.294  -33.134 -35.281  1.00 106.62 ? 512  ALA D N   1 
ATOM   14674 C CA  . ALA D 1 519 ? -7.954  -32.526 -35.476  1.00 100.93 ? 512  ALA D CA  1 
ATOM   14675 C C   . ALA D 1 519 ? -7.522  -31.644 -34.286  1.00 100.23 ? 512  ALA D C   1 
ATOM   14676 O O   . ALA D 1 519 ? -6.333  -31.285 -34.258  1.00 89.90  ? 512  ALA D O   1 
ATOM   14677 C CB  . ALA D 1 519 ? -7.936  -31.750 -36.777  1.00 95.53  ? 512  ALA D CB  1 
ATOM   14678 N N   . GLN D 1 520 ? -8.410  -31.314 -33.334  1.00 105.22 ? 513  GLN D N   1 
ATOM   14679 C CA  . GLN D 1 520 ? -8.101  -30.417 -32.173  1.00 101.80 ? 513  GLN D CA  1 
ATOM   14680 C C   . GLN D 1 520 ? -8.355  -31.141 -30.836  1.00 101.22 ? 513  GLN D C   1 
ATOM   14681 O O   . GLN D 1 520 ? -8.541  -30.435 -29.818  1.00 98.30  ? 513  GLN D O   1 
ATOM   14682 C CB  . GLN D 1 520 ? -8.928  -29.127 -32.279  1.00 100.28 ? 513  GLN D CB  1 
ATOM   14683 C CG  . GLN D 1 520 ? -8.515  -28.224 -33.441  1.00 101.13 ? 513  GLN D CG  1 
ATOM   14684 C CD  . GLN D 1 520 ? -9.664  -27.504 -34.109  1.00 99.63  ? 513  GLN D CD  1 
ATOM   14685 O OE1 . GLN D 1 520 ? -10.785 -27.480 -33.610  1.00 112.16 ? 513  GLN D OE1 1 
ATOM   14686 N NE2 . GLN D 1 520 ? -9.399  -26.908 -35.262  1.00 89.82  ? 513  GLN D NE2 1 
ATOM   14687 N N   . ALA D 1 521 ? -8.304  -32.483 -30.822  1.00 98.56  ? 514  ALA D N   1 
ATOM   14688 C CA  . ALA D 1 521 ? -8.745  -33.361 -29.706  1.00 93.64  ? 514  ALA D CA  1 
ATOM   14689 C C   . ALA D 1 521 ? -8.013  -32.996 -28.402  1.00 88.36  ? 514  ALA D C   1 
ATOM   14690 O O   . ALA D 1 521 ? -6.902  -33.416 -28.088  1.00 76.39  ? 514  ALA D O   1 
ATOM   14691 C CB  . ALA D 1 521 ? -8.544  -34.812 -30.084  1.00 88.49  ? 514  ALA D CB  1 
HETATM 14692 N N1  . PLP E 2 .   ? -3.961  3.065   -19.827  0.78 31.26  ? 601  PLP A N1  1 
HETATM 14693 C C2  . PLP E 2 .   ? -4.819  3.687   -19.015  0.78 32.38  ? 601  PLP A C2  1 
HETATM 14694 C C2A . PLP E 2 .   ? -6.235  3.207   -18.932  0.78 31.74  ? 601  PLP A C2A 1 
HETATM 14695 C C3  . PLP E 2 .   ? -4.392  4.753   -18.204  0.78 32.95  ? 601  PLP A C3  1 
HETATM 14696 O O3  . PLP E 2 .   ? -5.319  5.332   -17.381  0.78 30.69  ? 601  PLP A O3  1 
HETATM 14697 C C4  . PLP E 2 .   ? -3.040  5.175   -18.274  0.78 32.39  ? 601  PLP A C4  1 
HETATM 14698 C C4A . PLP E 2 .   ? -2.593  6.304   -17.451  0.78 33.46  ? 601  PLP A C4A 1 
HETATM 14699 O O4A . PLP E 2 .   ? -3.292  7.189   -16.985  0.78 32.94  ? 601  PLP A O4A 1 
HETATM 14700 C C5  . PLP E 2 .   ? -2.155  4.494   -19.147  0.78 32.19  ? 601  PLP A C5  1 
HETATM 14701 C C6  . PLP E 2 .   ? -2.666  3.462   -19.895  0.78 32.89  ? 601  PLP A C6  1 
HETATM 14702 C C5A . PLP E 2 .   ? -0.709  4.894   -19.322  0.78 29.63  ? 601  PLP A C5A 1 
HETATM 14703 O O4P . PLP E 2 .   ? 0.168   4.543   -18.201  0.78 27.14  ? 601  PLP A O4P 1 
HETATM 14704 P P   . PLP E 2 .   ? 1.670   5.107   -18.191  0.78 26.91  ? 601  PLP A P   1 
HETATM 14705 O O1P . PLP E 2 .   ? 2.320   4.692   -19.472  0.78 27.34  ? 601  PLP A O1P 1 
HETATM 14706 O O2P . PLP E 2 .   ? 2.387   4.517   -17.013  0.78 24.95  ? 601  PLP A O2P 1 
HETATM 14707 O O3P . PLP E 2 .   ? 1.479   6.596   -18.102  0.78 28.35  ? 601  PLP A O3P 1 
HETATM 14708 N N1  . PLP F 2 .   ? 18.138  0.502   -27.324  0.75 32.85  ? 601  PLP B N1  1 
HETATM 14709 C C2  . PLP F 2 .   ? 19.262  -0.189  -27.085  0.75 31.90  ? 601  PLP B C2  1 
HETATM 14710 C C2A . PLP F 2 .   ? 20.526  0.211   -27.775  0.75 29.30  ? 601  PLP B C2A 1 
HETATM 14711 C C3  . PLP F 2 .   ? 19.248  -1.288  -26.200  0.75 32.58  ? 601  PLP B C3  1 
HETATM 14712 O O3  . PLP F 2 .   ? 20.403  -1.965  -26.007  0.75 32.78  ? 601  PLP B O3  1 
HETATM 14713 C C4  . PLP F 2 .   ? 18.037  -1.654  -25.559  0.75 33.19  ? 601  PLP B C4  1 
HETATM 14714 C C4A . PLP F 2 .   ? 18.001  -2.811  -24.650  0.75 33.45  ? 601  PLP B C4A 1 
HETATM 14715 O O4A . PLP F 2 .   ? 18.723  -3.791  -24.692  0.75 33.70  ? 601  PLP B O4A 1 
HETATM 14716 C C5  . PLP F 2 .   ? 16.877  -0.894  -25.831  0.75 31.20  ? 601  PLP B C5  1 
HETATM 14717 C C6  . PLP F 2 .   ? 16.982  0.165   -26.700  0.75 31.42  ? 601  PLP B C6  1 
HETATM 14718 C C5A . PLP F 2 .   ? 15.556  -1.210  -25.185  0.75 30.82  ? 601  PLP B C5A 1 
HETATM 14719 O O4P . PLP F 2 .   ? 15.565  -0.789  -23.781  0.75 28.27  ? 601  PLP B O4P 1 
HETATM 14720 P P   . PLP F 2 .   ? 14.622  -1.449  -22.689  0.75 25.77  ? 601  PLP B P   1 
HETATM 14721 O O1P . PLP F 2 .   ? 13.179  -1.275  -23.179  0.75 25.72  ? 601  PLP B O1P 1 
HETATM 14722 O O2P . PLP F 2 .   ? 14.923  -0.664  -21.438  0.75 25.66  ? 601  PLP B O2P 1 
HETATM 14723 O O3P . PLP F 2 .   ? 15.048  -2.895  -22.614  0.75 25.19  ? 601  PLP B O3P 1 
HETATM 14724 N N1  . PLP G 2 .   ? 4.085   3.209   -68.024  0.75 25.68  ? 601  PLP C N1  1 
HETATM 14725 C C2  . PLP G 2 .   ? 4.882   3.912   -68.836  0.75 27.47  ? 601  PLP C C2  1 
HETATM 14726 C C2A . PLP G 2 .   ? 6.324   3.536   -68.972  0.75 26.22  ? 601  PLP C C2A 1 
HETATM 14727 C C3  . PLP G 2 .   ? 4.371   4.981   -69.592  0.75 27.82  ? 601  PLP C C3  1 
HETATM 14728 O O3  . PLP G 2 .   ? 5.230   5.651   -70.406  0.75 25.88  ? 601  PLP C O3  1 
HETATM 14729 C C4  . PLP G 2 .   ? 3.002   5.321   -69.478  0.75 28.31  ? 601  PLP C C4  1 
HETATM 14730 C C4A . PLP G 2 .   ? 2.493   6.461   -70.254  0.75 29.59  ? 601  PLP C C4A 1 
HETATM 14731 O O4A . PLP G 2 .   ? 3.093   7.501   -70.489  0.75 29.12  ? 601  PLP C O4A 1 
HETATM 14732 C C5  . PLP G 2 .   ? 2.179   4.549   -68.615  0.75 26.39  ? 601  PLP C C5  1 
HETATM 14733 C C6  . PLP G 2 .   ? 2.765   3.513   -67.928  0.75 26.48  ? 601  PLP C C6  1 
HETATM 14734 C C5A . PLP G 2 .   ? 0.709   4.834   -68.421  0.75 24.30  ? 601  PLP C C5A 1 
HETATM 14735 O O4P . PLP G 2 .   ? -0.124  4.426   -69.556  0.75 22.58  ? 601  PLP C O4P 1 
HETATM 14736 P P   . PLP G 2 .   ? -1.638  4.946   -69.609  0.75 23.07  ? 601  PLP C P   1 
HETATM 14737 O O1P . PLP G 2 .   ? -2.304  4.352   -70.811  0.75 22.30  ? 601  PLP C O1P 1 
HETATM 14738 O O2P . PLP G 2 .   ? -1.491  6.448   -69.667  0.75 23.79  ? 601  PLP C O2P 1 
HETATM 14739 O O3P . PLP G 2 .   ? -2.307  4.470   -68.378  0.75 23.51  ? 601  PLP C O3P 1 
HETATM 14740 N N1  . PLP H 2 .   ? -18.014 0.596   -60.505  0.78 41.11  ? 601  PLP D N1  1 
HETATM 14741 C C2  . PLP H 2 .   ? -19.166 -0.073  -60.622  0.78 41.20  ? 601  PLP D C2  1 
HETATM 14742 C C2A . PLP H 2 .   ? -20.360 0.414   -59.859  0.78 38.42  ? 601  PLP D C2A 1 
HETATM 14743 C C3  . PLP H 2 .   ? -19.250 -1.205  -61.478  0.78 39.88  ? 601  PLP D C3  1 
HETATM 14744 O O3  . PLP H 2 .   ? -20.440 -1.842  -61.576  0.78 38.24  ? 601  PLP D O3  1 
HETATM 14745 C C4  . PLP H 2 .   ? -18.095 -1.647  -62.175  0.78 39.14  ? 601  PLP D C4  1 
HETATM 14746 C C4A . PLP H 2 .   ? -18.142 -2.832  -63.055  0.78 39.35  ? 601  PLP D C4A 1 
HETATM 14747 O O4A . PLP H 2 .   ? -18.960 -3.738  -63.045  0.78 36.06  ? 601  PLP D O4A 1 
HETATM 14748 C C5  . PLP H 2 .   ? -16.899 -0.911  -62.015  0.78 36.76  ? 601  PLP D C5  1 
HETATM 14749 C C6  . PLP H 2 .   ? -16.913 0.181   -61.181  0.78 38.63  ? 601  PLP D C6  1 
HETATM 14750 C C5A . PLP H 2 .   ? -15.627 -1.290  -62.725  0.78 34.81  ? 601  PLP D C5A 1 
HETATM 14751 O O4P . PLP H 2 .   ? -15.566 -0.721  -64.072  0.78 31.54  ? 601  PLP D O4P 1 
HETATM 14752 P P   . PLP H 2 .   ? -14.505 -1.286  -65.126  0.78 28.72  ? 601  PLP D P   1 
HETATM 14753 O O1P . PLP H 2 .   ? -14.772 -0.505  -66.387  0.78 27.86  ? 601  PLP D O1P 1 
HETATM 14754 O O2P . PLP H 2 .   ? -14.875 -2.752  -65.222  0.78 28.38  ? 601  PLP D O2P 1 
HETATM 14755 O O3P . PLP H 2 .   ? -13.092 -1.059  -64.585  0.78 27.39  ? 601  PLP D O3P 1 
HETATM 14756 O O   . HOH I 3 .   ? -10.659 -1.708  -43.954  1.00 48.51  ? 701  HOH A O   1 
HETATM 14757 O O   . HOH I 3 .   ? -2.322  17.243  -30.890  1.00 22.30  ? 702  HOH A O   1 
HETATM 14758 O O   . HOH I 3 .   ? 5.624   28.733  -18.375  1.00 48.58  ? 703  HOH A O   1 
HETATM 14759 O O   . HOH I 3 .   ? -6.697  0.188   6.064    1.00 25.26  ? 704  HOH A O   1 
HETATM 14760 O O   . HOH I 3 .   ? -27.429 25.441  -3.992   1.00 55.11  ? 705  HOH A O   1 
HETATM 14761 O O   . HOH I 3 .   ? -21.253 -13.424 -35.859  1.00 38.49  ? 706  HOH A O   1 
HETATM 14762 O O   . HOH I 3 .   ? -11.148 -2.484  -9.073   1.00 10.71  ? 707  HOH A O   1 
HETATM 14763 O O   . HOH I 3 .   ? 17.880  -0.921  2.307    1.00 16.67  ? 708  HOH A O   1 
HETATM 14764 O O   . HOH I 3 .   ? 10.391  -4.119  -24.320  1.00 41.88  ? 709  HOH A O   1 
HETATM 14765 O O   . HOH I 3 .   ? -14.473 -12.970 -11.383  1.00 41.20  ? 710  HOH A O   1 
HETATM 14766 O O   . HOH I 3 .   ? 10.813  1.573   6.261    1.00 27.52  ? 711  HOH A O   1 
HETATM 14767 O O   . HOH I 3 .   ? -4.796  6.940   -6.106   1.00 54.01  ? 712  HOH A O   1 
HETATM 14768 O O   . HOH I 3 .   ? 17.038  -10.568 -4.111   1.00 26.86  ? 713  HOH A O   1 
HETATM 14769 O O   . HOH I 3 .   ? 16.538  8.729   5.653    1.00 20.96  ? 714  HOH A O   1 
HETATM 14770 O O   . HOH I 3 .   ? 26.246  15.919  -0.034   1.00 37.46  ? 715  HOH A O   1 
HETATM 14771 O O   . HOH I 3 .   ? -18.815 0.032   -28.039  1.00 13.76  ? 716  HOH A O   1 
HETATM 14772 O O   . HOH I 3 .   ? -1.469  3.953   -39.846  1.00 22.88  ? 717  HOH A O   1 
HETATM 14773 O O   . HOH I 3 .   ? -27.946 -5.036  -28.632  1.00 47.96  ? 718  HOH A O   1 
HETATM 14774 O O   . HOH I 3 .   ? -17.127 -6.523  -14.328  1.00 30.05  ? 719  HOH A O   1 
HETATM 14775 O O   . HOH I 3 .   ? -12.830 20.492  4.738    1.00 24.73  ? 720  HOH A O   1 
HETATM 14776 O O   . HOH I 3 .   ? -5.875  -16.678 -12.555  1.00 6.70   ? 721  HOH A O   1 
HETATM 14777 O O   . HOH I 3 .   ? 1.965   25.788  -2.010   1.00 44.49  ? 722  HOH A O   1 
HETATM 14778 O O   . HOH I 3 .   ? 12.564  31.054  -10.573  1.00 54.85  ? 723  HOH A O   1 
HETATM 14779 O O   . HOH I 3 .   ? 1.104   -15.489 -13.688  1.00 19.87  ? 724  HOH A O   1 
HETATM 14780 O O   . HOH I 3 .   ? -6.366  5.103   6.398    1.00 21.46  ? 725  HOH A O   1 
HETATM 14781 O O   . HOH I 3 .   ? -19.662 -11.483 -17.352  1.00 41.36  ? 726  HOH A O   1 
HETATM 14782 O O   . HOH I 3 .   ? -17.122 7.440   -26.994  1.00 19.17  ? 727  HOH A O   1 
HETATM 14783 O O   . HOH I 3 .   ? 4.721   15.857  -9.226   1.00 23.84  ? 728  HOH A O   1 
HETATM 14784 O O   . HOH I 3 .   ? -2.125  29.728  -17.504  1.00 45.90  ? 729  HOH A O   1 
HETATM 14785 O O   . HOH I 3 .   ? -9.094  -9.332  1.684    1.00 30.57  ? 730  HOH A O   1 
HETATM 14786 O O   . HOH I 3 .   ? -25.663 -4.066  -21.554  1.00 27.62  ? 731  HOH A O   1 
HETATM 14787 O O   . HOH I 3 .   ? -20.310 -3.474  -18.301  1.00 23.34  ? 732  HOH A O   1 
HETATM 14788 O O   . HOH I 3 .   ? 28.226  19.560  -1.503   1.00 42.92  ? 733  HOH A O   1 
HETATM 14789 O O   . HOH I 3 .   ? -5.041  4.620   -34.255  1.00 30.69  ? 734  HOH A O   1 
HETATM 14790 O O   . HOH I 3 .   ? -3.139  31.796  -12.238  1.00 39.04  ? 735  HOH A O   1 
HETATM 14791 O O   . HOH I 3 .   ? -24.712 2.473   -25.823  1.00 37.23  ? 736  HOH A O   1 
HETATM 14792 O O   . HOH I 3 .   ? 2.378   23.716  -8.497   1.00 59.20  ? 737  HOH A O   1 
HETATM 14793 O O   . HOH I 3 .   ? -24.143 10.109  -10.816  1.00 36.11  ? 738  HOH A O   1 
HETATM 14794 O O   . HOH I 3 .   ? 6.841   -13.205 -18.526  1.00 13.72  ? 739  HOH A O   1 
HETATM 14795 O O   . HOH I 3 .   ? -1.332  30.615  -10.671  1.00 59.84  ? 740  HOH A O   1 
HETATM 14796 O O   . HOH I 3 .   ? -10.470 -7.213  -0.344   1.00 28.32  ? 741  HOH A O   1 
HETATM 14797 O O   . HOH I 3 .   ? 9.812   -8.211  -30.613  1.00 22.31  ? 742  HOH A O   1 
HETATM 14798 O O   . HOH I 3 .   ? -21.278 5.451   -26.615  1.00 32.87  ? 743  HOH A O   1 
HETATM 14799 O O   . HOH I 3 .   ? -17.512 -10.177 -48.293  1.00 34.84  ? 744  HOH A O   1 
HETATM 14800 O O   . HOH I 3 .   ? -21.797 31.272  -2.724   1.00 41.76  ? 745  HOH A O   1 
HETATM 14801 O O   . HOH I 3 .   ? -19.515 0.708   -35.733  1.00 38.66  ? 746  HOH A O   1 
HETATM 14802 O O   . HOH I 3 .   ? -1.021  14.567  8.578    1.00 54.31  ? 747  HOH A O   1 
HETATM 14803 O O   . HOH I 3 .   ? -22.512 -4.895  -40.368  1.00 17.52  ? 748  HOH A O   1 
HETATM 14804 O O   . HOH I 3 .   ? 17.174  -0.092  -20.366  1.00 31.14  ? 749  HOH A O   1 
HETATM 14805 O O   . HOH I 3 .   ? -20.817 4.795   2.110    1.00 16.64  ? 750  HOH A O   1 
HETATM 14806 O O   . HOH I 3 .   ? -17.939 6.481   -6.081   1.00 9.60   ? 751  HOH A O   1 
HETATM 14807 O O   . HOH I 3 .   ? 1.808   -17.201 -32.723  1.00 53.54  ? 752  HOH A O   1 
HETATM 14808 O O   . HOH I 3 .   ? 5.516   -21.002 -28.538  1.00 30.62  ? 753  HOH A O   1 
HETATM 14809 O O   . HOH I 3 .   ? -17.593 -0.523  -5.857   1.00 26.84  ? 754  HOH A O   1 
HETATM 14810 O O   . HOH I 3 .   ? 14.822  -12.671 -15.388  1.00 20.71  ? 755  HOH A O   1 
HETATM 14811 O O   . HOH I 3 .   ? -24.632 -8.483  -21.117  1.00 18.09  ? 756  HOH A O   1 
HETATM 14812 O O   . HOH I 3 .   ? -23.445 28.964  -2.609   1.00 34.10  ? 757  HOH A O   1 
HETATM 14813 O O   . HOH I 3 .   ? 6.029   4.441   5.676    1.00 44.60  ? 758  HOH A O   1 
HETATM 14814 O O   . HOH I 3 .   ? -23.557 3.717   -18.541  1.00 57.82  ? 759  HOH A O   1 
HETATM 14815 O O   . HOH I 3 .   ? 2.843   2.399   -8.011   1.00 18.49  ? 760  HOH A O   1 
HETATM 14816 O O   . HOH I 3 .   ? -7.167  17.363  -32.238  1.00 72.00  ? 761  HOH A O   1 
HETATM 14817 O O   . HOH I 3 .   ? -15.245 1.166   4.955    1.00 24.11  ? 762  HOH A O   1 
HETATM 14818 O O   . HOH I 3 .   ? -7.110  -9.761  -43.280  1.00 31.42  ? 763  HOH A O   1 
HETATM 14819 O O   . HOH I 3 .   ? 4.470   28.087  -3.875   1.00 64.02  ? 764  HOH A O   1 
HETATM 14820 O O   . HOH I 3 .   ? -7.312  15.189  -38.986  1.00 30.71  ? 765  HOH A O   1 
HETATM 14821 O O   . HOH I 3 .   ? -20.901 21.148  3.627    1.00 22.45  ? 766  HOH A O   1 
HETATM 14822 O O   . HOH I 3 .   ? -13.784 -0.368  -41.273  1.00 42.46  ? 767  HOH A O   1 
HETATM 14823 O O   . HOH I 3 .   ? -3.150  16.367  8.804    1.00 42.33  ? 768  HOH A O   1 
HETATM 14824 O O   . HOH I 3 .   ? 2.515   -25.505 -19.535  1.00 31.35  ? 769  HOH A O   1 
HETATM 14825 O O   . HOH I 3 .   ? 8.432   -10.689 -16.910  1.00 18.32  ? 770  HOH A O   1 
HETATM 14826 O O   . HOH I 3 .   ? 6.254   24.843  -2.499   1.00 28.79  ? 771  HOH A O   1 
HETATM 14827 O O   . HOH I 3 .   ? 18.528  25.546  -3.577   1.00 34.92  ? 772  HOH A O   1 
HETATM 14828 O O   . HOH I 3 .   ? -21.795 -0.914  -3.604   1.00 24.02  ? 773  HOH A O   1 
HETATM 14829 O O   . HOH I 3 .   ? 25.034  16.939  1.966    1.00 40.19  ? 774  HOH A O   1 
HETATM 14830 O O   . HOH I 3 .   ? -22.470 -9.940  -27.197  1.00 11.32  ? 775  HOH A O   1 
HETATM 14831 O O   . HOH I 3 .   ? -0.219  22.799  5.873    1.00 36.12  ? 776  HOH A O   1 
HETATM 14832 O O   . HOH I 3 .   ? 0.124   8.194   7.778    1.00 41.53  ? 777  HOH A O   1 
HETATM 14833 O O   . HOH I 3 .   ? 11.390  31.704  -4.370   1.00 40.93  ? 778  HOH A O   1 
HETATM 14834 O O   . HOH I 3 .   ? 13.051  -9.956  -9.852   1.00 23.72  ? 779  HOH A O   1 
HETATM 14835 O O   . HOH I 3 .   ? -12.258 -11.516 -35.860  1.00 23.27  ? 780  HOH A O   1 
HETATM 14836 O O   . HOH I 3 .   ? 7.210   -5.217  3.907    1.00 41.15  ? 781  HOH A O   1 
HETATM 14837 O O   . HOH I 3 .   ? -24.879 -4.107  -34.716  1.00 39.08  ? 782  HOH A O   1 
HETATM 14838 O O   . HOH I 3 .   ? 8.172   -18.053 -29.254  1.00 35.72  ? 783  HOH A O   1 
HETATM 14839 O O   . HOH I 3 .   ? -21.476 -11.636 -37.884  1.00 40.10  ? 784  HOH A O   1 
HETATM 14840 O O   . HOH I 3 .   ? -5.623  20.242  3.695    1.00 46.34  ? 785  HOH A O   1 
HETATM 14841 O O   . HOH I 3 .   ? 2.936   7.849   5.106    1.00 8.90   ? 786  HOH A O   1 
HETATM 14842 O O   . HOH I 3 .   ? 10.164  17.472  -20.263  1.00 20.00  ? 787  HOH A O   1 
HETATM 14843 O O   . HOH I 3 .   ? 3.019   4.367   -0.800   1.00 3.83   ? 788  HOH A O   1 
HETATM 14844 O O   . HOH I 3 .   ? -22.878 -15.526 -30.290  1.00 27.82  ? 789  HOH A O   1 
HETATM 14845 O O   . HOH I 3 .   ? 9.349   -12.442 -22.290  1.00 39.38  ? 790  HOH A O   1 
HETATM 14846 O O   . HOH I 3 .   ? -4.649  -20.332 -19.348  1.00 21.81  ? 791  HOH A O   1 
HETATM 14847 O O   . HOH I 3 .   ? -9.497  3.462   -17.036  1.00 16.09  ? 792  HOH A O   1 
HETATM 14848 O O   . HOH I 3 .   ? -0.847  1.802   -4.753   1.00 10.97  ? 793  HOH A O   1 
HETATM 14849 O O   . HOH I 3 .   ? -7.348  -16.944 -24.344  1.00 23.59  ? 794  HOH A O   1 
HETATM 14850 O O   . HOH I 3 .   ? -10.615 1.162   -25.906  1.00 15.96  ? 795  HOH A O   1 
HETATM 14851 O O   . HOH I 3 .   ? 17.468  -12.049 -13.686  1.00 38.40  ? 796  HOH A O   1 
HETATM 14852 O O   . HOH I 3 .   ? -11.472 21.212  -16.687  1.00 38.31  ? 797  HOH A O   1 
HETATM 14853 O O   . HOH I 3 .   ? -10.382 7.216   -20.684  1.00 14.37  ? 798  HOH A O   1 
HETATM 14854 O O   . HOH I 3 .   ? 7.988   20.561  3.741    1.00 50.51  ? 799  HOH A O   1 
HETATM 14855 O O   . HOH I 3 .   ? -13.278 -2.580  -44.453  1.00 27.66  ? 800  HOH A O   1 
HETATM 14856 O O   . HOH I 3 .   ? -2.441  6.566   -38.410  1.00 24.23  ? 801  HOH A O   1 
HETATM 14857 O O   . HOH I 3 .   ? -21.251 1.403   0.775    1.00 29.32  ? 802  HOH A O   1 
HETATM 14858 O O   . HOH I 3 .   ? -17.670 -1.320  2.118    1.00 21.94  ? 803  HOH A O   1 
HETATM 14859 O O   . HOH I 3 .   ? -11.989 7.198   10.238   1.00 29.85  ? 804  HOH A O   1 
HETATM 14860 O O   . HOH I 3 .   ? -4.338  23.073  -8.913   1.00 45.47  ? 805  HOH A O   1 
HETATM 14861 O O   . HOH I 3 .   ? 22.463  17.607  2.862    1.00 47.16  ? 806  HOH A O   1 
HETATM 14862 O O   . HOH I 3 .   ? -24.103 -4.202  -38.255  1.00 28.23  ? 807  HOH A O   1 
HETATM 14863 O O   . HOH I 3 .   ? -7.662  6.273   -18.495  1.00 28.25  ? 808  HOH A O   1 
HETATM 14864 O O   . HOH I 3 .   ? -0.497  -21.987 -28.453  1.00 33.71  ? 809  HOH A O   1 
HETATM 14865 O O   . HOH I 3 .   ? -0.821  -2.756  -36.678  1.00 18.84  ? 810  HOH A O   1 
HETATM 14866 O O   . HOH I 3 .   ? -25.757 -0.434  -28.610  1.00 28.71  ? 811  HOH A O   1 
HETATM 14867 O O   . HOH I 3 .   ? 1.888   32.937  -17.576  1.00 65.29  ? 812  HOH A O   1 
HETATM 14868 O O   . HOH I 3 .   ? -11.716 2.073   -23.282  1.00 12.90  ? 813  HOH A O   1 
HETATM 14869 O O   . HOH I 3 .   ? 3.108   -14.970 -34.538  1.00 42.36  ? 814  HOH A O   1 
HETATM 14870 O O   . HOH I 3 .   ? 1.917   6.451   -21.431  1.00 15.85  ? 815  HOH A O   1 
HETATM 14871 O O   . HOH I 3 .   ? -7.834  1.342   -16.578  1.00 13.16  ? 816  HOH A O   1 
HETATM 14872 O O   . HOH I 3 .   ? -13.698 -13.903 -42.358  1.00 45.35  ? 817  HOH A O   1 
HETATM 14873 O O   . HOH I 3 .   ? -20.326 -10.681 -41.962  1.00 51.70  ? 818  HOH A O   1 
HETATM 14874 O O   . HOH I 3 .   ? 4.063   12.580  -38.123  1.00 16.43  ? 819  HOH A O   1 
HETATM 14875 O O   . HOH I 3 .   ? -1.352  12.956  -5.950   1.00 40.46  ? 820  HOH A O   1 
HETATM 14876 O O   . HOH I 3 .   ? 10.123  -1.634  -12.958  1.00 13.97  ? 821  HOH A O   1 
HETATM 14877 O O   . HOH I 3 .   ? -3.179  -3.744  -38.419  1.00 16.04  ? 822  HOH A O   1 
HETATM 14878 O O   . HOH I 3 .   ? 6.128   -4.099  -23.090  1.00 22.52  ? 823  HOH A O   1 
HETATM 14879 O O   . HOH I 3 .   ? -0.919  -14.697 -41.912  1.00 24.78  ? 824  HOH A O   1 
HETATM 14880 O O   . HOH I 3 .   ? -2.654  22.215  5.376    1.00 45.55  ? 825  HOH A O   1 
HETATM 14881 O O   . HOH I 3 .   ? 16.794  -11.150 -6.801   1.00 25.62  ? 826  HOH A O   1 
HETATM 14882 O O   . HOH I 3 .   ? -12.229 -8.065  -5.330   1.00 35.22  ? 827  HOH A O   1 
HETATM 14883 O O   . HOH I 3 .   ? 9.887   -8.737  -18.029  1.00 38.12  ? 828  HOH A O   1 
HETATM 14884 O O   . HOH I 3 .   ? 5.209   -17.874 -31.498  1.00 27.18  ? 829  HOH A O   1 
HETATM 14885 O O   . HOH I 3 .   ? -26.660 12.690  -2.774   1.00 25.41  ? 830  HOH A O   1 
HETATM 14886 O O   . HOH I 3 .   ? -14.459 27.552  -20.307  1.00 64.08  ? 831  HOH A O   1 
HETATM 14887 O O   . HOH I 3 .   ? -7.378  -1.674  -41.989  1.00 41.45  ? 832  HOH A O   1 
HETATM 14888 O O   . HOH I 3 .   ? 0.743   7.969   -20.314  1.00 18.78  ? 833  HOH A O   1 
HETATM 14889 O O   . HOH I 3 .   ? -8.083  3.121   5.546    1.00 25.53  ? 834  HOH A O   1 
HETATM 14890 O O   . HOH I 3 .   ? 24.629  -17.366 -20.331  1.00 22.00  ? 835  HOH A O   1 
HETATM 14891 O O   . HOH I 3 .   ? -22.257 11.156  1.973    1.00 39.47  ? 836  HOH A O   1 
HETATM 14892 O O   . HOH I 3 .   ? -2.623  -22.707 -29.811  1.00 23.43  ? 837  HOH A O   1 
HETATM 14893 O O   . HOH I 3 .   ? 13.943  -7.516  -17.292  1.00 33.32  ? 838  HOH A O   1 
HETATM 14894 O O   . HOH I 3 .   ? -17.830 30.541  -0.632   1.00 37.33  ? 839  HOH A O   1 
HETATM 14895 O O   . HOH I 3 .   ? 8.950   -4.000  -13.587  1.00 13.76  ? 840  HOH A O   1 
HETATM 14896 O O   . HOH I 3 .   ? 7.207   29.634  -5.339   1.00 52.05  ? 841  HOH A O   1 
HETATM 14897 O O   . HOH I 3 .   ? -9.005  -16.068 -34.653  1.00 32.40  ? 842  HOH A O   1 
HETATM 14898 O O   . HOH I 3 .   ? -22.183 18.995  2.023    1.00 23.77  ? 843  HOH A O   1 
HETATM 14899 O O   . HOH I 3 .   ? -16.061 -13.710 -18.871  1.00 10.19  ? 844  HOH A O   1 
HETATM 14900 O O   . HOH I 3 .   ? -22.969 31.081  -10.343  1.00 30.46  ? 845  HOH A O   1 
HETATM 14901 O O   . HOH I 3 .   ? -16.433 7.740   -24.354  1.00 25.10  ? 846  HOH A O   1 
HETATM 14902 O O   . HOH I 3 .   ? -18.569 2.397   -4.682   1.00 21.55  ? 847  HOH A O   1 
HETATM 14903 O O   . HOH I 3 .   ? 20.060  26.610  -16.881  1.00 45.42  ? 848  HOH A O   1 
HETATM 14904 O O   . HOH I 3 .   ? -3.565  -1.182  -12.242  1.00 18.28  ? 849  HOH A O   1 
HETATM 14905 O O   . HOH I 3 .   ? -5.235  21.035  -10.127  1.00 30.83  ? 850  HOH A O   1 
HETATM 14906 O O   . HOH I 3 .   ? 0.304   -0.942  5.552    1.00 45.75  ? 851  HOH A O   1 
HETATM 14907 O O   . HOH I 3 .   ? -4.134  0.941   -10.807  1.00 15.29  ? 852  HOH A O   1 
HETATM 14908 O O   . HOH I 3 .   ? -1.577  8.938   -18.300  1.00 48.20  ? 853  HOH A O   1 
HETATM 14909 O O   . HOH I 3 .   ? -16.968 3.710   -35.767  1.00 55.81  ? 854  HOH A O   1 
HETATM 14910 O O   . HOH I 3 .   ? -10.206 3.905   6.838    1.00 13.00  ? 855  HOH A O   1 
HETATM 14911 O O   . HOH I 3 .   ? 1.305   3.445   -14.664  1.00 36.92  ? 856  HOH A O   1 
HETATM 14912 O O   . HOH I 3 .   ? 27.027  21.663  -3.418   1.00 31.31  ? 857  HOH A O   1 
HETATM 14913 O O   . HOH I 3 .   ? -26.337 19.452  -11.775  1.00 37.19  ? 858  HOH A O   1 
HETATM 14914 O O   . HOH I 3 .   ? 22.977  -4.546  2.532    1.00 13.32  ? 859  HOH A O   1 
HETATM 14915 O O   . HOH I 3 .   ? 14.432  -12.322 -2.156   1.00 24.53  ? 860  HOH A O   1 
HETATM 14916 O O   . HOH I 3 .   ? -11.794 -15.253 -28.766  1.00 33.61  ? 861  HOH A O   1 
HETATM 14917 O O   . HOH I 3 .   ? -7.753  11.622  9.318    1.00 27.47  ? 862  HOH A O   1 
HETATM 14918 O O   . HOH I 3 .   ? -7.314  -9.090  -40.656  1.00 17.41  ? 863  HOH A O   1 
HETATM 14919 O O   . HOH I 3 .   ? -13.853 -9.232  -37.812  1.00 6.47   ? 864  HOH A O   1 
HETATM 14920 O O   . HOH I 3 .   ? -14.968 20.178  9.715    1.00 31.95  ? 865  HOH A O   1 
HETATM 14921 O O   . HOH I 3 .   ? -6.327  21.223  -6.294   1.00 29.71  ? 866  HOH A O   1 
HETATM 14922 O O   . HOH I 3 .   ? -0.113  3.675   -2.967   1.00 20.89  ? 867  HOH A O   1 
HETATM 14923 O O   . HOH I 3 .   ? 23.815  -7.190  -0.067   1.00 18.16  ? 868  HOH A O   1 
HETATM 14924 O O   . HOH I 3 .   ? 9.711   22.845  4.532    1.00 61.11  ? 869  HOH A O   1 
HETATM 14925 O O   . HOH I 3 .   ? -2.124  -9.216  -35.979  1.00 7.91   ? 870  HOH A O   1 
HETATM 14926 O O   . HOH I 3 .   ? -17.190 16.802  -21.556  1.00 58.88  ? 871  HOH A O   1 
HETATM 14927 O O   . HOH I 3 .   ? -6.060  2.951   -9.379   1.00 12.89  ? 872  HOH A O   1 
HETATM 14928 O O   . HOH I 3 .   ? -19.798 -16.205 -28.704  1.00 37.93  ? 873  HOH A O   1 
HETATM 14929 O O   . HOH I 3 .   ? 4.518   7.386   -1.789   1.00 8.48   ? 874  HOH A O   1 
HETATM 14930 O O   . HOH I 3 .   ? -15.670 -15.274 -16.587  1.00 38.41  ? 875  HOH A O   1 
HETATM 14931 O O   . HOH I 3 .   ? -11.707 -12.381 -10.545  1.00 45.13  ? 876  HOH A O   1 
HETATM 14932 O O   . HOH I 3 .   ? -26.650 21.459  -14.330  1.00 31.77  ? 877  HOH A O   1 
HETATM 14933 O O   . HOH I 3 .   ? -8.720  -10.443 -6.925   1.00 30.46  ? 878  HOH A O   1 
HETATM 14934 O O   . HOH I 3 .   ? -20.735 7.461   -16.941  1.00 16.31  ? 879  HOH A O   1 
HETATM 14935 O O   . HOH I 3 .   ? 27.524  22.407  -5.818   1.00 33.30  ? 880  HOH A O   1 
HETATM 14936 O O   . HOH I 3 .   ? -24.456 2.178   -16.454  1.00 28.01  ? 881  HOH A O   1 
HETATM 14937 O O   . HOH I 3 .   ? -25.677 1.192   -32.178  1.00 27.03  ? 882  HOH A O   1 
HETATM 14938 O O   . HOH I 3 .   ? -5.884  -13.183 -43.671  1.00 42.28  ? 883  HOH A O   1 
HETATM 14939 O O   . HOH I 3 .   ? -1.860  -6.776  -36.672  1.00 24.35  ? 884  HOH A O   1 
HETATM 14940 O O   . HOH I 3 .   ? -7.771  -3.113  -46.591  1.00 23.08  ? 885  HOH A O   1 
HETATM 14941 O O   . HOH I 3 .   ? 14.714  -0.399  6.959    1.00 61.06  ? 886  HOH A O   1 
HETATM 14942 O O   . HOH I 3 .   ? 12.064  4.789   4.411    1.00 17.50  ? 887  HOH A O   1 
HETATM 14943 O O   . HOH I 3 .   ? -2.513  15.481  -38.070  1.00 39.60  ? 888  HOH A O   1 
HETATM 14944 O O   . HOH I 3 .   ? -5.064  2.873   -40.465  1.00 28.20  ? 889  HOH A O   1 
HETATM 14945 O O   . HOH I 3 .   ? 15.782  33.621  -0.823   1.00 56.43  ? 890  HOH A O   1 
HETATM 14946 O O   . HOH I 3 .   ? -17.603 -3.971  0.331    1.00 43.89  ? 891  HOH A O   1 
HETATM 14947 O O   . HOH I 3 .   ? -5.090  2.917   -37.745  1.00 22.02  ? 892  HOH A O   1 
HETATM 14948 O O   . HOH I 3 .   ? 9.090   -13.853 -25.464  1.00 59.22  ? 893  HOH A O   1 
HETATM 14949 O O   . HOH I 3 .   ? -24.306 0.408   -36.346  1.00 34.62  ? 894  HOH A O   1 
HETATM 14950 O O   . HOH I 3 .   ? -6.469  20.568  -13.202  1.00 36.73  ? 895  HOH A O   1 
HETATM 14951 O O   . HOH I 3 .   ? -10.769 -15.920 -26.746  1.00 33.75  ? 896  HOH A O   1 
HETATM 14952 O O   . HOH I 3 .   ? -3.857  10.542  5.916    1.00 17.74  ? 897  HOH A O   1 
HETATM 14953 O O   . HOH I 3 .   ? -10.967 6.247   8.387    1.00 22.81  ? 898  HOH A O   1 
HETATM 14954 O O   . HOH I 3 .   ? -22.327 -10.253 -15.458  1.00 40.53  ? 899  HOH A O   1 
HETATM 14955 O O   . HOH I 3 .   ? 13.858  -11.123 -7.539   1.00 24.11  ? 900  HOH A O   1 
HETATM 14956 O O   . HOH I 3 .   ? -12.265 10.553  -28.314  1.00 34.30  ? 901  HOH A O   1 
HETATM 14957 O O   . HOH I 3 .   ? -13.461 -18.015 -30.486  1.00 33.59  ? 902  HOH A O   1 
HETATM 14958 O O   . HOH I 3 .   ? -24.444 -7.268  -30.075  1.00 22.40  ? 903  HOH A O   1 
HETATM 14959 O O   . HOH I 3 .   ? 11.182  -15.807 -32.959  1.00 31.55  ? 904  HOH A O   1 
HETATM 14960 O O   . HOH I 3 .   ? 29.413  19.893  -17.430  1.00 40.58  ? 905  HOH A O   1 
HETATM 14961 O O   . HOH I 3 .   ? -13.499 -11.798 -13.550  1.00 22.51  ? 906  HOH A O   1 
HETATM 14962 O O   . HOH I 3 .   ? -24.307 -1.569  -25.185  1.00 29.65  ? 907  HOH A O   1 
HETATM 14963 O O   . HOH I 3 .   ? 8.594   1.204   6.570    1.00 23.82  ? 908  HOH A O   1 
HETATM 14964 O O   . HOH I 3 .   ? -22.007 7.485   -11.457  1.00 30.46  ? 909  HOH A O   1 
HETATM 14965 O O   . HOH I 3 .   ? 11.651  -8.705  -19.648  1.00 34.87  ? 910  HOH A O   1 
HETATM 14966 O O   . HOH I 3 .   ? -5.225  -21.285 -21.805  1.00 16.11  ? 911  HOH A O   1 
HETATM 14967 O O   . HOH I 3 .   ? -17.783 -4.604  -5.014   1.00 32.50  ? 912  HOH A O   1 
HETATM 14968 O O   . HOH I 3 .   ? 7.956   11.600  4.570    1.00 16.14  ? 913  HOH A O   1 
HETATM 14969 O O   . HOH I 3 .   ? 16.368  -15.479 -29.559  1.00 59.29  ? 914  HOH A O   1 
HETATM 14970 O O   . HOH I 3 .   ? -23.065 17.330  0.234    1.00 35.96  ? 915  HOH A O   1 
HETATM 14971 O O   . HOH I 3 .   ? -3.696  19.406  7.515    1.00 24.85  ? 916  HOH A O   1 
HETATM 14972 O O   . HOH I 3 .   ? -23.068 5.677   -28.877  1.00 18.42  ? 917  HOH A O   1 
HETATM 14973 O O   . HOH I 3 .   ? -0.269  -11.437 5.326    1.00 30.17  ? 918  HOH A O   1 
HETATM 14974 O O   . HOH I 3 .   ? 9.517   -7.443  3.686    1.00 24.65  ? 919  HOH A O   1 
HETATM 14975 O O   . HOH I 3 .   ? -5.130  -19.999 -14.625  1.00 50.10  ? 920  HOH A O   1 
HETATM 14976 O O   . HOH I 3 .   ? -6.177  23.560  -17.681  1.00 38.63  ? 921  HOH A O   1 
HETATM 14977 O O   . HOH I 3 .   ? 27.002  16.251  -2.284   1.00 29.33  ? 922  HOH A O   1 
HETATM 14978 O O   . HOH I 3 .   ? 31.274  18.366  -14.727  1.00 33.73  ? 923  HOH A O   1 
HETATM 14979 O O   . HOH I 3 .   ? -21.652 4.625   -21.558  1.00 42.21  ? 924  HOH A O   1 
HETATM 14980 O O   . HOH I 3 .   ? -8.410  17.978  -26.706  1.00 61.79  ? 925  HOH A O   1 
HETATM 14981 O O   . HOH I 3 .   ? -14.843 4.697   -37.068  1.00 42.39  ? 926  HOH A O   1 
HETATM 14982 O O   . HOH I 3 .   ? -15.241 -1.643  -39.490  1.00 34.17  ? 927  HOH A O   1 
HETATM 14983 O O   . HOH I 3 .   ? 17.801  19.170  6.715    1.00 35.38  ? 928  HOH A O   1 
HETATM 14984 O O   . HOH I 3 .   ? 17.315  -4.864  -14.301  1.00 60.21  ? 929  HOH A O   1 
HETATM 14985 O O   . HOH I 3 .   ? 11.401  8.885   7.228    1.00 39.72  ? 930  HOH A O   1 
HETATM 14986 O O   . HOH I 3 .   ? -1.764  9.780   -16.072  1.00 43.26  ? 931  HOH A O   1 
HETATM 14987 O O   . HOH I 3 .   ? -24.929 13.626  -10.163  1.00 22.09  ? 932  HOH A O   1 
HETATM 14988 O O   . HOH I 3 .   ? -2.545  1.342   5.101    1.00 26.39  ? 933  HOH A O   1 
HETATM 14989 O O   . HOH I 3 .   ? -9.275  15.698  -29.425  1.00 30.88  ? 934  HOH A O   1 
HETATM 14990 O O   . HOH I 3 .   ? -18.311 -4.969  -15.892  1.00 35.84  ? 935  HOH A O   1 
HETATM 14991 O O   . HOH I 3 .   ? -19.029 15.579  5.019    1.00 30.32  ? 936  HOH A O   1 
HETATM 14992 O O   . HOH I 3 .   ? 6.530   -20.156 -32.047  1.00 34.90  ? 937  HOH A O   1 
HETATM 14993 O O   . HOH I 3 .   ? -24.626 -15.036 -35.043  1.00 29.76  ? 938  HOH A O   1 
HETATM 14994 O O   . HOH I 3 .   ? -19.583 4.415   -6.250   1.00 23.77  ? 939  HOH A O   1 
HETATM 14995 O O   . HOH I 3 .   ? -14.114 -11.545 -37.902  1.00 31.04  ? 940  HOH A O   1 
HETATM 14996 O O   . HOH I 3 .   ? 5.263   9.904   5.107    1.00 29.41  ? 941  HOH A O   1 
HETATM 14997 O O   . HOH I 3 .   ? -6.881  -7.075  -43.031  1.00 16.37  ? 942  HOH A O   1 
HETATM 14998 O O   . HOH I 3 .   ? -14.350 0.076   -38.613  1.00 30.15  ? 943  HOH A O   1 
HETATM 14999 O O   . HOH I 3 .   ? 13.946  -10.155 -17.724  1.00 55.47  ? 944  HOH A O   1 
HETATM 15000 O O   . HOH I 3 .   ? -10.611 -16.654 -30.661  1.00 56.05  ? 945  HOH A O   1 
HETATM 15001 O O   . HOH I 3 .   ? 18.324  24.949  -1.098   1.00 28.43  ? 946  HOH A O   1 
HETATM 15002 O O   . HOH I 3 .   ? -20.474 -6.873  -8.213   1.00 17.65  ? 947  HOH A O   1 
HETATM 15003 O O   . HOH I 3 .   ? -15.590 24.129  6.928    1.00 48.72  ? 948  HOH A O   1 
HETATM 15004 O O   . HOH I 3 .   ? -7.536  14.724  8.011    1.00 54.00  ? 949  HOH A O   1 
HETATM 15005 O O   . HOH I 3 .   ? -22.465 26.758  1.055    1.00 49.19  ? 950  HOH A O   1 
HETATM 15006 O O   . HOH I 3 .   ? -1.318  17.440  -36.247  1.00 39.54  ? 951  HOH A O   1 
HETATM 15007 O O   . HOH I 3 .   ? -23.929 -7.768  -16.236  1.00 34.90  ? 952  HOH A O   1 
HETATM 15008 O O   . HOH I 3 .   ? -23.713 -16.384 -32.182  1.00 33.64  ? 953  HOH A O   1 
HETATM 15009 O O   . HOH I 3 .   ? -15.552 25.889  -22.475  1.00 42.10  ? 954  HOH A O   1 
HETATM 15010 O O   . HOH I 3 .   ? 15.826  -11.886 -4.452   1.00 75.73  ? 955  HOH A O   1 
HETATM 15011 O O   . HOH I 3 .   ? -14.227 -2.178  -42.435  1.00 44.08  ? 956  HOH A O   1 
HETATM 15012 O O   . HOH I 3 .   ? -20.850 -12.939 -40.649  1.00 49.04  ? 957  HOH A O   1 
HETATM 15013 O O   . HOH I 3 .   ? -19.471 6.952   -23.642  1.00 25.78  ? 958  HOH A O   1 
HETATM 15014 O O   . HOH I 3 .   ? -5.135  7.439   7.680    1.00 9.26   ? 959  HOH A O   1 
HETATM 15015 O O   . HOH I 3 .   ? 8.385   7.070   8.497    1.00 33.08  ? 960  HOH A O   1 
HETATM 15016 O O   . HOH I 3 .   ? -1.157  -4.745  5.910    1.00 13.45  ? 961  HOH A O   1 
HETATM 15017 O O   . HOH I 3 .   ? -13.309 -17.471 -12.699  1.00 38.48  ? 962  HOH A O   1 
HETATM 15018 O O   . HOH I 3 .   ? 2.561   9.374   8.710    1.00 39.19  ? 963  HOH A O   1 
HETATM 15019 O O   . HOH I 3 .   ? 7.946   -2.681  -23.790  1.00 53.64  ? 964  HOH A O   1 
HETATM 15020 O O   . HOH I 3 .   ? -23.801 -9.851  -43.014  1.00 33.39  ? 965  HOH A O   1 
HETATM 15021 O O   . HOH I 3 .   ? -4.499  5.169   -36.762  1.00 38.34  ? 966  HOH A O   1 
HETATM 15022 O O   . HOH I 3 .   ? -29.478 -3.783  -33.558  1.00 31.90  ? 967  HOH A O   1 
HETATM 15023 O O   . HOH I 3 .   ? 9.182   -12.157 -18.189  1.00 16.81  ? 968  HOH A O   1 
HETATM 15024 O O   . HOH I 3 .   ? -1.030  -19.870 -30.054  1.00 48.13  ? 969  HOH A O   1 
HETATM 15025 O O   . HOH I 3 .   ? -4.943  1.986   -42.081  1.00 4.64   ? 970  HOH A O   1 
HETATM 15026 O O   . HOH I 3 .   ? -19.504 -14.292 -21.633  1.00 25.87  ? 971  HOH A O   1 
HETATM 15027 O O   . HOH I 3 .   ? 9.604   30.506  -2.526   1.00 67.18  ? 972  HOH A O   1 
HETATM 15028 O O   . HOH I 3 .   ? -23.576 -8.692  -36.977  1.00 37.88  ? 973  HOH A O   1 
HETATM 15029 O O   . HOH I 3 .   ? 3.364   -15.638 -37.179  1.00 38.01  ? 974  HOH A O   1 
HETATM 15030 O O   . HOH I 3 .   ? -8.095  -19.734 -35.754  1.00 34.57  ? 975  HOH A O   1 
HETATM 15031 O O   . HOH I 3 .   ? 0.982   33.477  -11.130  1.00 45.32  ? 976  HOH A O   1 
HETATM 15032 O O   . HOH I 3 .   ? -18.886 24.533  3.722    1.00 43.30  ? 977  HOH A O   1 
HETATM 15033 O O   . HOH I 3 .   ? -20.127 -16.252 -26.036  1.00 44.80  ? 978  HOH A O   1 
HETATM 15034 O O   . HOH I 3 .   ? -13.561 2.761   6.553    1.00 42.27  ? 979  HOH A O   1 
HETATM 15035 O O   . HOH I 3 .   ? 7.538   17.042  -21.266  1.00 39.00  ? 980  HOH A O   1 
HETATM 15036 O O   . HOH I 3 .   ? 0.384   20.673  7.887    1.00 40.13  ? 981  HOH A O   1 
HETATM 15037 O O   . HOH I 3 .   ? -6.497  -19.499 -38.593  1.00 43.24  ? 982  HOH A O   1 
HETATM 15038 O O   . HOH I 3 .   ? 3.197   6.279   7.133    1.00 26.53  ? 983  HOH A O   1 
HETATM 15039 O O   . HOH I 3 .   ? -13.844 -15.813 -15.171  1.00 52.03  ? 984  HOH A O   1 
HETATM 15040 O O   . HOH I 3 .   ? -4.733  2.668   6.601    1.00 44.86  ? 985  HOH A O   1 
HETATM 15041 O O   . HOH I 3 .   ? -5.624  16.059  7.193    1.00 37.73  ? 986  HOH A O   1 
HETATM 15042 O O   . HOH I 3 .   ? -14.028 21.994  7.174    1.00 28.59  ? 987  HOH A O   1 
HETATM 15043 O O   . HOH I 3 .   ? 8.007   3.925   7.154    1.00 40.44  ? 988  HOH A O   1 
HETATM 15044 O O   . HOH I 3 .   ? -10.985 12.149  -26.435  1.00 25.41  ? 989  HOH A O   1 
HETATM 15045 O O   . HOH I 3 .   ? 10.013  27.619  4.801    1.00 39.79  ? 990  HOH A O   1 
HETATM 15046 O O   . HOH I 3 .   ? -4.767  17.593  -32.860  1.00 38.57  ? 991  HOH A O   1 
HETATM 15047 O O   . HOH I 3 .   ? -4.475  18.398  5.489    1.00 56.20  ? 992  HOH A O   1 
HETATM 15048 O O   . HOH I 3 .   ? -8.777  13.341  9.742    1.00 28.54  ? 993  HOH A O   1 
HETATM 15049 O O   . HOH I 3 .   ? -18.774 -11.927 -44.214  1.00 30.44  ? 994  HOH A O   1 
HETATM 15050 O O   . HOH I 3 .   ? -15.912 1.671   -37.104  1.00 60.29  ? 995  HOH A O   1 
HETATM 15051 O O   . HOH I 3 .   ? -2.132  8.973   -40.989  1.00 32.34  ? 996  HOH A O   1 
HETATM 15052 O O   . HOH I 3 .   ? -25.148 -8.975  -18.752  1.00 44.61  ? 997  HOH A O   1 
HETATM 15053 O O   . HOH I 3 .   ? -3.371  8.933   7.817    1.00 21.05  ? 998  HOH A O   1 
HETATM 15054 O O   . HOH I 3 .   ? -19.163 -1.895  -6.165   1.00 39.23  ? 999  HOH A O   1 
HETATM 15055 O O   . HOH I 3 .   ? -24.330 -11.189 -17.643  1.00 48.93  ? 1000 HOH A O   1 
HETATM 15056 O O   . HOH I 3 .   ? 19.855  30.077  3.115    1.00 69.69  ? 1001 HOH A O   1 
HETATM 15057 O O   . HOH I 3 .   ? -3.232  -24.061 -23.312  1.00 45.38  ? 1002 HOH A O   1 
HETATM 15058 O O   . HOH I 3 .   ? -4.866  17.801  -17.929  1.00 42.85  ? 1003 HOH A O   1 
HETATM 15059 O O   . HOH I 3 .   ? 19.885  28.239  0.139    1.00 31.01  ? 1004 HOH A O   1 
HETATM 15060 O O   . HOH I 3 .   ? -3.544  -3.958  -40.649  1.00 22.72  ? 1005 HOH A O   1 
HETATM 15061 O O   . HOH I 3 .   ? -18.493 -13.149 -19.267  1.00 38.35  ? 1006 HOH A O   1 
HETATM 15062 O O   . HOH I 3 .   ? 18.854  -1.509  4.966    1.00 41.04  ? 1007 HOH A O   1 
HETATM 15063 O O   . HOH I 3 .   ? -4.960  -22.220 -17.254  1.00 37.20  ? 1008 HOH A O   1 
HETATM 15064 O O   . HOH I 3 .   ? 5.364   -2.750  8.205    1.00 24.07  ? 1009 HOH A O   1 
HETATM 15065 O O   . HOH I 3 .   ? -22.272 1.552   -36.104  1.00 16.42  ? 1010 HOH A O   1 
HETATM 15066 O O   . HOH I 3 .   ? -2.880  -19.935 -11.800  1.00 41.09  ? 1011 HOH A O   1 
HETATM 15067 O O   . HOH I 3 .   ? -17.255 -1.307  4.402    1.00 28.53  ? 1012 HOH A O   1 
HETATM 15068 O O   . HOH I 3 .   ? -15.415 -15.830 -20.240  1.00 34.32  ? 1013 HOH A O   1 
HETATM 15069 O O   . HOH I 3 .   ? -24.950 -2.699  -23.164  1.00 59.58  ? 1014 HOH A O   1 
HETATM 15070 O O   . HOH I 3 .   ? 31.451  18.135  -16.842  1.00 45.21  ? 1015 HOH A O   1 
HETATM 15071 O O   . HOH I 3 .   ? 5.275   -15.345 -32.762  1.00 53.47  ? 1016 HOH A O   1 
HETATM 15072 O O   . HOH I 3 .   ? -2.705  -14.020 -43.355  1.00 15.28  ? 1017 HOH A O   1 
HETATM 15073 O O   . HOH I 3 .   ? -9.355  -17.554 -28.527  1.00 53.40  ? 1018 HOH A O   1 
HETATM 15074 O O   . HOH I 3 .   ? 8.596   -18.177 -32.033  1.00 22.31  ? 1019 HOH A O   1 
HETATM 15075 O O   . HOH I 3 .   ? -26.697 -12.309 -21.643  1.00 30.76  ? 1020 HOH A O   1 
HETATM 15076 O O   . HOH I 3 .   ? 11.179  -11.188 -20.137  1.00 63.01  ? 1021 HOH A O   1 
HETATM 15077 O O   . HOH I 3 .   ? -5.077  11.052  9.746    1.00 27.11  ? 1022 HOH A O   1 
HETATM 15078 O O   . HOH I 3 .   ? 21.687  24.457  -21.320  1.00 29.08  ? 1023 HOH A O   1 
HETATM 15079 O O   . HOH I 3 .   ? -0.933  1.526   7.321    1.00 34.62  ? 1024 HOH A O   1 
HETATM 15080 O O   . HOH I 3 .   ? 19.985  29.621  -6.917   1.00 40.31  ? 1025 HOH A O   1 
HETATM 15081 O O   . HOH I 3 .   ? -4.810  -10.224 -44.523  1.00 29.38  ? 1026 HOH A O   1 
HETATM 15082 O O   . HOH I 3 .   ? -10.112 -8.599  -3.432   1.00 20.65  ? 1027 HOH A O   1 
HETATM 15083 O O   . HOH I 3 .   ? -17.494 30.757  -14.628  1.00 41.52  ? 1028 HOH A O   1 
HETATM 15084 O O   . HOH I 3 .   ? -8.131  -20.064 -22.860  1.00 34.01  ? 1029 HOH A O   1 
HETATM 15085 O O   . HOH I 3 .   ? -10.889 14.344  11.916   1.00 40.82  ? 1030 HOH A O   1 
HETATM 15086 O O   . HOH I 3 .   ? -21.662 7.149   -14.248  1.00 41.35  ? 1031 HOH A O   1 
HETATM 15087 O O   . HOH I 3 .   ? -9.152  20.590  5.354    1.00 35.48  ? 1032 HOH A O   1 
HETATM 15088 O O   . HOH I 3 .   ? -8.913  12.796  13.182   1.00 26.16  ? 1033 HOH A O   1 
HETATM 15089 O O   . HOH I 3 .   ? -1.280  5.869   8.715    1.00 22.43  ? 1034 HOH A O   1 
HETATM 15090 O O   . HOH I 3 .   ? -2.016  4.972   -42.189  1.00 43.04  ? 1035 HOH A O   1 
HETATM 15091 O O   . HOH I 3 .   ? -9.002  -10.911 -4.418   1.00 25.27  ? 1036 HOH A O   1 
HETATM 15092 O O   . HOH I 3 .   ? -3.265  -22.164 -13.119  1.00 38.32  ? 1037 HOH A O   1 
HETATM 15093 O O   . HOH I 3 .   ? 0.743   3.968   7.990    1.00 17.00  ? 1038 HOH A O   1 
HETATM 15094 O O   . HOH I 3 .   ? -4.626  21.298  -19.951  1.00 50.86  ? 1039 HOH A O   1 
HETATM 15095 O O   . HOH I 3 .   ? 1.301   -11.742 -42.424  1.00 33.01  ? 1040 HOH A O   1 
HETATM 15096 O O   . HOH I 3 .   ? 2.634   -3.363  9.163    1.00 35.09  ? 1041 HOH A O   1 
HETATM 15097 O O   . HOH I 3 .   ? -3.738  4.785   9.041    1.00 27.38  ? 1042 HOH A O   1 
HETATM 15098 O O   . HOH I 3 .   ? -10.627 17.465  11.207   1.00 15.26  ? 1043 HOH A O   1 
HETATM 15099 O O   . HOH I 3 .   ? 0.964   6.935   12.202   1.00 40.81  ? 1044 HOH A O   1 
HETATM 15100 O O   . HOH I 3 .   ? -8.608  19.337  10.337   1.00 35.25  ? 1045 HOH A O   1 
HETATM 15101 O O   . HOH I 3 .   ? -1.048  4.298   12.105   1.00 37.57  ? 1046 HOH A O   1 
HETATM 15102 O O   . HOH J 3 .   ? 12.005  15.290  -54.593  1.00 62.52  ? 701  HOH B O   1 
HETATM 15103 O O   . HOH J 3 .   ? 27.658  -1.381  -43.484  1.00 30.70  ? 702  HOH B O   1 
HETATM 15104 O O   . HOH J 3 .   ? 9.790   -13.984 -34.698  1.00 30.36  ? 703  HOH B O   1 
HETATM 15105 O O   . HOH J 3 .   ? 46.638  -21.534 -29.275  1.00 50.49  ? 704  HOH B O   1 
HETATM 15106 O O   . HOH J 3 .   ? 34.151  7.827   -41.981  1.00 33.69  ? 705  HOH B O   1 
HETATM 15107 O O   . HOH J 3 .   ? 24.143  9.018   -2.182   1.00 32.36  ? 706  HOH B O   1 
HETATM 15108 O O   . HOH J 3 .   ? 24.009  20.179  -23.187  1.00 23.71  ? 707  HOH B O   1 
HETATM 15109 O O   . HOH J 3 .   ? 11.040  -26.713 -9.266   1.00 30.24  ? 708  HOH B O   1 
HETATM 15110 O O   . HOH J 3 .   ? 14.415  4.927   3.545    1.00 29.63  ? 709  HOH B O   1 
HETATM 15111 O O   . HOH J 3 .   ? 29.908  10.698  -5.530   1.00 44.76  ? 710  HOH B O   1 
HETATM 15112 O O   . HOH J 3 .   ? 20.159  -19.899 -14.626  1.00 24.46  ? 711  HOH B O   1 
HETATM 15113 O O   . HOH J 3 .   ? 7.414   -0.086  -41.017  1.00 40.30  ? 712  HOH B O   1 
HETATM 15114 O O   . HOH J 3 .   ? 6.231   12.223  -48.206  1.00 33.92  ? 713  HOH B O   1 
HETATM 15115 O O   . HOH J 3 .   ? 45.624  -15.639 -20.564  1.00 26.39  ? 714  HOH B O   1 
HETATM 15116 O O   . HOH J 3 .   ? 20.693  -18.137 -29.680  1.00 32.07  ? 715  HOH B O   1 
HETATM 15117 O O   . HOH J 3 .   ? 36.653  -25.837 -33.465  1.00 37.52  ? 716  HOH B O   1 
HETATM 15118 O O   . HOH J 3 .   ? 19.015  23.858  -28.092  1.00 26.80  ? 717  HOH B O   1 
HETATM 15119 O O   . HOH J 3 .   ? 22.097  -2.397  -28.866  1.00 25.68  ? 718  HOH B O   1 
HETATM 15120 O O   . HOH J 3 .   ? 17.839  19.892  -33.426  1.00 20.33  ? 719  HOH B O   1 
HETATM 15121 O O   . HOH J 3 .   ? 14.737  19.273  -46.304  1.00 40.82  ? 720  HOH B O   1 
HETATM 15122 O O   . HOH J 3 .   ? 15.663  -27.223 -5.138   1.00 9.35   ? 721  HOH B O   1 
HETATM 15123 O O   . HOH J 3 .   ? 41.028  -16.333 -34.002  1.00 39.51  ? 722  HOH B O   1 
HETATM 15124 O O   . HOH J 3 .   ? 25.301  7.899   -52.097  1.00 25.38  ? 723  HOH B O   1 
HETATM 15125 O O   . HOH J 3 .   ? 30.128  6.003   -23.563  1.00 39.55  ? 724  HOH B O   1 
HETATM 15126 O O   . HOH J 3 .   ? 4.958   24.154  -28.743  1.00 14.90  ? 725  HOH B O   1 
HETATM 15127 O O   . HOH J 3 .   ? 5.576   3.033   -47.380  1.00 20.19  ? 726  HOH B O   1 
HETATM 15128 O O   . HOH J 3 .   ? 27.348  -1.594  -46.767  1.00 17.95  ? 727  HOH B O   1 
HETATM 15129 O O   . HOH J 3 .   ? 2.586   -9.531  -39.421  1.00 33.83  ? 728  HOH B O   1 
HETATM 15130 O O   . HOH J 3 .   ? 39.011  -15.937 -37.121  1.00 37.16  ? 729  HOH B O   1 
HETATM 15131 O O   . HOH J 3 .   ? 17.689  18.816  -20.001  1.00 33.36  ? 730  HOH B O   1 
HETATM 15132 O O   . HOH J 3 .   ? 3.333   -0.143  -41.542  1.00 27.09  ? 731  HOH B O   1 
HETATM 15133 O O   . HOH J 3 .   ? 22.546  -2.548  -7.951   1.00 15.80  ? 732  HOH B O   1 
HETATM 15134 O O   . HOH J 3 .   ? 11.067  -25.305 -19.673  1.00 37.22  ? 733  HOH B O   1 
HETATM 15135 O O   . HOH J 3 .   ? 26.734  -24.949 -16.692  1.00 75.48  ? 734  HOH B O   1 
HETATM 15136 O O   . HOH J 3 .   ? 40.720  -25.415 -18.977  1.00 41.88  ? 735  HOH B O   1 
HETATM 15137 O O   . HOH J 3 .   ? 38.225  -20.358 -13.350  1.00 62.63  ? 736  HOH B O   1 
HETATM 15138 O O   . HOH J 3 .   ? 31.981  6.693   -36.344  1.00 27.72  ? 737  HOH B O   1 
HETATM 15139 O O   . HOH J 3 .   ? 46.461  -6.635  -21.933  1.00 5.31   ? 738  HOH B O   1 
HETATM 15140 O O   . HOH J 3 .   ? 11.509  -13.703 7.114    1.00 22.24  ? 739  HOH B O   1 
HETATM 15141 O O   . HOH J 3 .   ? 7.503   -11.095 6.448    1.00 54.88  ? 740  HOH B O   1 
HETATM 15142 O O   . HOH J 3 .   ? 4.570   -15.448 7.174    1.00 54.98  ? 741  HOH B O   1 
HETATM 15143 O O   . HOH J 3 .   ? 24.326  3.631   -43.401  1.00 12.99  ? 742  HOH B O   1 
HETATM 15144 O O   . HOH J 3 .   ? 25.647  0.305   -11.463  1.00 14.35  ? 743  HOH B O   1 
HETATM 15145 O O   . HOH J 3 .   ? 39.473  -5.759  -32.659  1.00 30.37  ? 744  HOH B O   1 
HETATM 15146 O O   . HOH J 3 .   ? 2.636   21.667  -27.578  1.00 25.45  ? 745  HOH B O   1 
HETATM 15147 O O   . HOH J 3 .   ? 22.609  2.171   2.205    1.00 29.39  ? 746  HOH B O   1 
HETATM 15148 O O   . HOH J 3 .   ? 36.794  9.276   -16.805  1.00 30.57  ? 747  HOH B O   1 
HETATM 15149 O O   . HOH J 3 .   ? 21.644  -26.808 -18.383  1.00 51.11  ? 748  HOH B O   1 
HETATM 15150 O O   . HOH J 3 .   ? 9.929   5.703   -51.975  1.00 15.35  ? 749  HOH B O   1 
HETATM 15151 O O   . HOH J 3 .   ? 44.209  -29.433 -26.160  1.00 68.43  ? 750  HOH B O   1 
HETATM 15152 O O   . HOH J 3 .   ? 20.614  -0.974  1.523    1.00 22.81  ? 751  HOH B O   1 
HETATM 15153 O O   . HOH J 3 .   ? 20.144  8.286   -55.292  1.00 23.58  ? 752  HOH B O   1 
HETATM 15154 O O   . HOH J 3 .   ? 24.124  -2.940  -41.264  1.00 14.66  ? 753  HOH B O   1 
HETATM 15155 O O   . HOH J 3 .   ? 43.091  -27.271 -24.406  1.00 39.77  ? 754  HOH B O   1 
HETATM 15156 O O   . HOH J 3 .   ? 33.041  12.071  -41.623  1.00 20.80  ? 755  HOH B O   1 
HETATM 15157 O O   . HOH J 3 .   ? 31.584  9.458   -31.681  1.00 25.98  ? 756  HOH B O   1 
HETATM 15158 O O   . HOH J 3 .   ? 6.887   7.896   -46.036  1.00 28.43  ? 757  HOH B O   1 
HETATM 15159 O O   . HOH J 3 .   ? 45.857  -21.812 -23.344  1.00 52.30  ? 758  HOH B O   1 
HETATM 15160 O O   . HOH J 3 .   ? 8.075   16.307  -48.206  1.00 49.46  ? 759  HOH B O   1 
HETATM 15161 O O   . HOH J 3 .   ? 37.320  3.410   -25.575  1.00 33.40  ? 760  HOH B O   1 
HETATM 15162 O O   . HOH J 3 .   ? 27.967  13.137  -44.992  1.00 31.52  ? 761  HOH B O   1 
HETATM 15163 O O   . HOH J 3 .   ? 33.078  -3.637  -35.129  1.00 39.43  ? 762  HOH B O   1 
HETATM 15164 O O   . HOH J 3 .   ? 33.898  15.511  -28.313  1.00 54.89  ? 763  HOH B O   1 
HETATM 15165 O O   . HOH J 3 .   ? 7.500   6.020   -48.296  1.00 48.03  ? 764  HOH B O   1 
HETATM 15166 O O   . HOH J 3 .   ? 22.299  -18.121 2.610    1.00 43.75  ? 765  HOH B O   1 
HETATM 15167 O O   . HOH J 3 .   ? 3.380   18.326  -35.341  1.00 53.52  ? 766  HOH B O   1 
HETATM 15168 O O   . HOH J 3 .   ? 41.760  1.611   -14.688  1.00 36.35  ? 767  HOH B O   1 
HETATM 15169 O O   . HOH J 3 .   ? 13.039  -13.995 -39.297  1.00 57.60  ? 768  HOH B O   1 
HETATM 15170 O O   . HOH J 3 .   ? 11.443  -16.518 7.780    1.00 59.79  ? 769  HOH B O   1 
HETATM 15171 O O   . HOH J 3 .   ? 20.926  -20.878 -7.112   1.00 16.09  ? 770  HOH B O   1 
HETATM 15172 O O   . HOH J 3 .   ? 21.374  20.463  -33.117  1.00 35.17  ? 771  HOH B O   1 
HETATM 15173 O O   . HOH J 3 .   ? 39.441  -16.755 -13.140  1.00 35.02  ? 772  HOH B O   1 
HETATM 15174 O O   . HOH J 3 .   ? 6.058   11.694  -18.157  1.00 31.09  ? 773  HOH B O   1 
HETATM 15175 O O   . HOH J 3 .   ? 35.208  13.539  -14.297  1.00 25.49  ? 774  HOH B O   1 
HETATM 15176 O O   . HOH J 3 .   ? 20.666  -21.483 -27.415  1.00 36.94  ? 775  HOH B O   1 
HETATM 15177 O O   . HOH J 3 .   ? 24.601  -8.868  -14.809  1.00 43.96  ? 776  HOH B O   1 
HETATM 15178 O O   . HOH J 3 .   ? 4.804   5.462   -16.691  1.00 28.04  ? 777  HOH B O   1 
HETATM 15179 O O   . HOH J 3 .   ? 4.645   10.295  -2.564   1.00 26.60  ? 778  HOH B O   1 
HETATM 15180 O O   . HOH J 3 .   ? 21.990  10.337  -0.775   1.00 42.53  ? 779  HOH B O   1 
HETATM 15181 O O   . HOH J 3 .   ? 29.782  14.398  -20.910  1.00 30.10  ? 780  HOH B O   1 
HETATM 15182 O O   . HOH J 3 .   ? 32.169  15.434  -35.808  1.00 31.98  ? 781  HOH B O   1 
HETATM 15183 O O   . HOH J 3 .   ? 48.623  -8.469  -27.693  1.00 28.13  ? 782  HOH B O   1 
HETATM 15184 O O   . HOH J 3 .   ? 7.992   11.902  -45.993  1.00 11.08  ? 783  HOH B O   1 
HETATM 15185 O O   . HOH J 3 .   ? 24.280  -0.120  -8.233   1.00 15.22  ? 784  HOH B O   1 
HETATM 15186 O O   . HOH J 3 .   ? 8.586   12.739  -17.771  1.00 34.14  ? 785  HOH B O   1 
HETATM 15187 O O   . HOH J 3 .   ? 45.742  -8.037  -33.822  1.00 14.92  ? 786  HOH B O   1 
HETATM 15188 O O   . HOH J 3 .   ? 23.369  -15.114 3.079    1.00 13.76  ? 787  HOH B O   1 
HETATM 15189 O O   . HOH J 3 .   ? 13.098  28.892  -23.489  1.00 39.62  ? 788  HOH B O   1 
HETATM 15190 O O   . HOH J 3 .   ? 16.430  -8.377  3.112    1.00 39.25  ? 789  HOH B O   1 
HETATM 15191 O O   . HOH J 3 .   ? 0.549   11.591  -27.520  1.00 12.30  ? 790  HOH B O   1 
HETATM 15192 O O   . HOH J 3 .   ? 5.102   6.266   -39.150  1.00 19.89  ? 791  HOH B O   1 
HETATM 15193 O O   . HOH J 3 .   ? 23.378  2.504   -27.459  1.00 20.89  ? 792  HOH B O   1 
HETATM 15194 O O   . HOH J 3 .   ? 5.632   11.402  -14.476  1.00 30.21  ? 793  HOH B O   1 
HETATM 15195 O O   . HOH J 3 .   ? 0.533   -8.839  -36.421  1.00 20.28  ? 794  HOH B O   1 
HETATM 15196 O O   . HOH J 3 .   ? 4.989   -11.164 -40.774  1.00 19.47  ? 795  HOH B O   1 
HETATM 15197 O O   . HOH J 3 .   ? 14.536  15.294  -45.272  1.00 22.92  ? 796  HOH B O   1 
HETATM 15198 O O   . HOH J 3 .   ? 18.214  -25.460 -8.723   1.00 24.02  ? 797  HOH B O   1 
HETATM 15199 O O   . HOH J 3 .   ? 13.011  19.381  -41.830  1.00 32.36  ? 798  HOH B O   1 
HETATM 15200 O O   . HOH J 3 .   ? 11.256  15.172  -2.672   1.00 24.29  ? 799  HOH B O   1 
HETATM 15201 O O   . HOH J 3 .   ? 33.586  11.329  -21.374  1.00 30.74  ? 800  HOH B O   1 
HETATM 15202 O O   . HOH J 3 .   ? 20.492  2.519   -49.757  1.00 31.52  ? 801  HOH B O   1 
HETATM 15203 O O   . HOH J 3 .   ? 42.266  5.029   -19.374  1.00 38.17  ? 802  HOH B O   1 
HETATM 15204 O O   . HOH J 3 .   ? 29.785  3.791   -48.135  1.00 24.72  ? 803  HOH B O   1 
HETATM 15205 O O   . HOH J 3 .   ? 3.772   21.889  -31.310  1.00 34.91  ? 804  HOH B O   1 
HETATM 15206 O O   . HOH J 3 .   ? 24.168  -25.467 -2.962   1.00 57.67  ? 805  HOH B O   1 
HETATM 15207 O O   . HOH J 3 .   ? 28.181  17.414  -34.281  1.00 38.13  ? 806  HOH B O   1 
HETATM 15208 O O   . HOH J 3 .   ? 13.635  -28.139 1.939    1.00 41.15  ? 807  HOH B O   1 
HETATM 15209 O O   . HOH J 3 .   ? 25.064  2.287   -14.001  1.00 12.84  ? 808  HOH B O   1 
HETATM 15210 O O   . HOH J 3 .   ? 11.707  8.034   -14.843  1.00 16.81  ? 809  HOH B O   1 
HETATM 15211 O O   . HOH J 3 .   ? 19.059  -6.551  -39.309  1.00 20.62  ? 810  HOH B O   1 
HETATM 15212 O O   . HOH J 3 .   ? 23.492  20.503  -37.067  1.00 33.80  ? 811  HOH B O   1 
HETATM 15213 O O   . HOH J 3 .   ? 5.660   16.255  -12.401  1.00 16.00  ? 812  HOH B O   1 
HETATM 15214 O O   . HOH J 3 .   ? 16.177  10.084  -60.363  1.00 32.99  ? 813  HOH B O   1 
HETATM 15215 O O   . HOH J 3 .   ? 5.312   -3.612  -40.892  1.00 25.22  ? 814  HOH B O   1 
HETATM 15216 O O   . HOH J 3 .   ? 46.145  -8.378  -28.503  1.00 26.31  ? 815  HOH B O   1 
HETATM 15217 O O   . HOH J 3 .   ? 13.352  -1.553  -19.463  1.00 26.35  ? 816  HOH B O   1 
HETATM 15218 O O   . HOH J 3 .   ? 41.218  -27.280 -20.773  1.00 65.41  ? 817  HOH B O   1 
HETATM 15219 O O   . HOH J 3 .   ? 24.025  -16.743 -23.552  1.00 27.81  ? 818  HOH B O   1 
HETATM 15220 O O   . HOH J 3 .   ? 10.985  13.761  -9.422   1.00 23.70  ? 819  HOH B O   1 
HETATM 15221 O O   . HOH J 3 .   ? 9.997   -0.946  -40.035  1.00 35.34  ? 820  HOH B O   1 
HETATM 15222 O O   . HOH J 3 .   ? 28.503  -16.881 -17.877  1.00 13.40  ? 821  HOH B O   1 
HETATM 15223 O O   . HOH J 3 .   ? 16.710  -16.244 8.051    1.00 36.06  ? 822  HOH B O   1 
HETATM 15224 O O   . HOH J 3 .   ? 19.711  -23.409 9.487    1.00 39.92  ? 823  HOH B O   1 
HETATM 15225 O O   . HOH J 3 .   ? 20.953  -14.171 -24.368  1.00 43.83  ? 824  HOH B O   1 
HETATM 15226 O O   . HOH J 3 .   ? 4.121   7.476   -22.138  1.00 27.90  ? 825  HOH B O   1 
HETATM 15227 O O   . HOH J 3 .   ? 13.986  15.807  -2.556   1.00 24.26  ? 826  HOH B O   1 
HETATM 15228 O O   . HOH J 3 .   ? 22.406  -3.616  -32.038  1.00 19.24  ? 827  HOH B O   1 
HETATM 15229 O O   . HOH J 3 .   ? 4.101   16.953  -23.995  1.00 35.70  ? 828  HOH B O   1 
HETATM 15230 O O   . HOH J 3 .   ? 38.943  1.914   -25.233  1.00 22.09  ? 829  HOH B O   1 
HETATM 15231 O O   . HOH J 3 .   ? 11.172  13.634  -58.607  1.00 30.42  ? 830  HOH B O   1 
HETATM 15232 O O   . HOH J 3 .   ? 25.248  -3.432  -38.820  1.00 27.65  ? 831  HOH B O   1 
HETATM 15233 O O   . HOH J 3 .   ? 6.706   12.734  -39.345  1.00 20.69  ? 832  HOH B O   1 
HETATM 15234 O O   . HOH J 3 .   ? 11.317  5.529   -13.531  1.00 16.99  ? 833  HOH B O   1 
HETATM 15235 O O   . HOH J 3 .   ? 8.092   7.619   -23.881  1.00 27.36  ? 834  HOH B O   1 
HETATM 15236 O O   . HOH J 3 .   ? 50.729  -11.636 -29.133  1.00 11.04  ? 835  HOH B O   1 
HETATM 15237 O O   . HOH J 3 .   ? 26.842  17.202  -46.559  1.00 25.76  ? 836  HOH B O   1 
HETATM 15238 O O   . HOH J 3 .   ? 9.813   15.552  -4.575   1.00 31.77  ? 837  HOH B O   1 
HETATM 15239 O O   . HOH J 3 .   ? 23.600  -16.998 -0.917   1.00 23.43  ? 838  HOH B O   1 
HETATM 15240 O O   . HOH J 3 .   ? 36.607  -0.974  -8.107   1.00 20.40  ? 839  HOH B O   1 
HETATM 15241 O O   . HOH J 3 .   ? 18.846  19.627  -37.112  1.00 47.01  ? 840  HOH B O   1 
HETATM 15242 O O   . HOH J 3 .   ? 24.162  0.623   -28.772  1.00 11.22  ? 841  HOH B O   1 
HETATM 15243 O O   . HOH J 3 .   ? 12.644  -2.998  -25.224  1.00 17.87  ? 842  HOH B O   1 
HETATM 15244 O O   . HOH J 3 .   ? 21.955  1.528   -35.161  1.00 13.40  ? 843  HOH B O   1 
HETATM 15245 O O   . HOH J 3 .   ? 5.734   7.367   -41.366  1.00 18.76  ? 844  HOH B O   1 
HETATM 15246 O O   . HOH J 3 .   ? 37.357  -2.984  -25.554  1.00 12.33  ? 845  HOH B O   1 
HETATM 15247 O O   . HOH J 3 .   ? 39.384  -8.113  -7.247   1.00 30.10  ? 846  HOH B O   1 
HETATM 15248 O O   . HOH J 3 .   ? 4.953   -12.380 5.862    1.00 29.91  ? 847  HOH B O   1 
HETATM 15249 O O   . HOH J 3 .   ? 17.224  -28.484 -12.214  1.00 50.12  ? 848  HOH B O   1 
HETATM 15250 O O   . HOH J 3 .   ? 33.905  -28.138 -26.864  1.00 32.52  ? 849  HOH B O   1 
HETATM 15251 O O   . HOH J 3 .   ? 42.778  -3.100  -26.692  1.00 20.25  ? 850  HOH B O   1 
HETATM 15252 O O   . HOH J 3 .   ? 8.144   24.305  -31.888  1.00 38.61  ? 851  HOH B O   1 
HETATM 15253 O O   . HOH J 3 .   ? 10.703  -21.062 -0.050   1.00 28.79  ? 852  HOH B O   1 
HETATM 15254 O O   . HOH J 3 .   ? 33.828  -6.300  -6.773   1.00 7.58   ? 853  HOH B O   1 
HETATM 15255 O O   . HOH J 3 .   ? 24.999  -18.632 -18.888  1.00 50.45  ? 854  HOH B O   1 
HETATM 15256 O O   . HOH J 3 .   ? 36.951  -18.600 -11.380  1.00 58.56  ? 855  HOH B O   1 
HETATM 15257 O O   . HOH J 3 .   ? 12.115  5.069   -51.261  1.00 23.90  ? 856  HOH B O   1 
HETATM 15258 O O   . HOH J 3 .   ? 18.050  -0.485  -48.159  1.00 16.09  ? 857  HOH B O   1 
HETATM 15259 O O   . HOH J 3 .   ? 24.488  -14.873 0.254    1.00 39.01  ? 858  HOH B O   1 
HETATM 15260 O O   . HOH J 3 .   ? 24.708  -8.404  -36.788  1.00 22.38  ? 859  HOH B O   1 
HETATM 15261 O O   . HOH J 3 .   ? 10.824  26.428  -32.098  1.00 52.47  ? 860  HOH B O   1 
HETATM 15262 O O   . HOH J 3 .   ? 15.398  -13.582 -31.897  1.00 60.90  ? 861  HOH B O   1 
HETATM 15263 O O   . HOH J 3 .   ? 47.513  -11.101 -15.196  1.00 26.75  ? 862  HOH B O   1 
HETATM 15264 O O   . HOH J 3 .   ? 2.144   -18.007 3.604    1.00 21.34  ? 863  HOH B O   1 
HETATM 15265 O O   . HOH J 3 .   ? 45.075  -0.480  -20.800  1.00 21.81  ? 864  HOH B O   1 
HETATM 15266 O O   . HOH J 3 .   ? 23.573  3.236   -20.437  1.00 19.83  ? 865  HOH B O   1 
HETATM 15267 O O   . HOH J 3 .   ? 22.092  -5.620  -8.362   1.00 25.28  ? 866  HOH B O   1 
HETATM 15268 O O   . HOH J 3 .   ? 22.010  5.507   -21.468  1.00 18.04  ? 867  HOH B O   1 
HETATM 15269 O O   . HOH J 3 .   ? 19.642  2.022   -36.610  1.00 6.95   ? 868  HOH B O   1 
HETATM 15270 O O   . HOH J 3 .   ? 28.939  12.575  -3.670   1.00 31.62  ? 869  HOH B O   1 
HETATM 15271 O O   . HOH J 3 .   ? 27.705  -5.504  -3.424   1.00 41.53  ? 870  HOH B O   1 
HETATM 15272 O O   . HOH J 3 .   ? 28.981  -16.728 -0.236   1.00 27.46  ? 871  HOH B O   1 
HETATM 15273 O O   . HOH J 3 .   ? 24.524  -24.286 -32.446  1.00 42.25  ? 872  HOH B O   1 
HETATM 15274 O O   . HOH J 3 .   ? 17.626  24.822  -30.113  1.00 36.15  ? 873  HOH B O   1 
HETATM 15275 O O   . HOH J 3 .   ? 30.378  15.120  -5.303   1.00 30.27  ? 874  HOH B O   1 
HETATM 15276 O O   . HOH J 3 .   ? 44.907  -8.389  -20.644  1.00 35.09  ? 875  HOH B O   1 
HETATM 15277 O O   . HOH J 3 .   ? 45.030  -13.426 -23.077  1.00 28.19  ? 876  HOH B O   1 
HETATM 15278 O O   . HOH J 3 .   ? 41.546  -2.139  -9.705   1.00 19.23  ? 877  HOH B O   1 
HETATM 15279 O O   . HOH J 3 .   ? 9.740   15.790  -52.143  1.00 27.22  ? 878  HOH B O   1 
HETATM 15280 O O   . HOH J 3 .   ? 26.271  -10.104 -0.037   1.00 21.59  ? 879  HOH B O   1 
HETATM 15281 O O   . HOH J 3 .   ? 33.754  -28.449 -22.238  1.00 44.46  ? 880  HOH B O   1 
HETATM 15282 O O   . HOH J 3 .   ? 17.453  20.311  -46.240  1.00 42.85  ? 881  HOH B O   1 
HETATM 15283 O O   . HOH J 3 .   ? 39.978  -0.376  -10.484  1.00 24.91  ? 882  HOH B O   1 
HETATM 15284 O O   . HOH J 3 .   ? 43.190  -11.393 -32.757  1.00 24.38  ? 883  HOH B O   1 
HETATM 15285 O O   . HOH J 3 .   ? 30.221  -11.202 -1.178   1.00 49.14  ? 884  HOH B O   1 
HETATM 15286 O O   . HOH J 3 .   ? 25.968  -20.552 -36.006  1.00 35.49  ? 885  HOH B O   1 
HETATM 15287 O O   . HOH J 3 .   ? 28.548  -2.432  -3.287   1.00 18.53  ? 886  HOH B O   1 
HETATM 15288 O O   . HOH J 3 .   ? 19.763  1.384   -13.707  1.00 13.33  ? 887  HOH B O   1 
HETATM 15289 O O   . HOH J 3 .   ? 7.332   0.800   -43.301  1.00 30.56  ? 888  HOH B O   1 
HETATM 15290 O O   . HOH J 3 .   ? 24.657  2.999   0.812    1.00 16.18  ? 889  HOH B O   1 
HETATM 15291 O O   . HOH J 3 .   ? 30.748  17.534  -48.058  1.00 35.91  ? 890  HOH B O   1 
HETATM 15292 O O   . HOH J 3 .   ? -4.765  18.210  -24.969  1.00 49.61  ? 891  HOH B O   1 
HETATM 15293 O O   . HOH J 3 .   ? 30.706  4.847   -44.500  1.00 16.55  ? 892  HOH B O   1 
HETATM 15294 O O   . HOH J 3 .   ? 26.247  1.112   -20.530  1.00 16.33  ? 893  HOH B O   1 
HETATM 15295 O O   . HOH J 3 .   ? -6.350  -16.414 -4.084   1.00 28.76  ? 894  HOH B O   1 
HETATM 15296 O O   . HOH J 3 .   ? 17.780  15.092  -55.293  1.00 31.03  ? 895  HOH B O   1 
HETATM 15297 O O   . HOH J 3 .   ? 17.315  -27.008 -23.251  1.00 46.97  ? 896  HOH B O   1 
HETATM 15298 O O   . HOH J 3 .   ? 38.772  -0.734  -26.494  1.00 27.51  ? 897  HOH B O   1 
HETATM 15299 O O   . HOH J 3 .   ? 23.969  -25.955 -0.697   1.00 39.11  ? 898  HOH B O   1 
HETATM 15300 O O   . HOH J 3 .   ? 25.534  -6.111  -1.586   1.00 32.81  ? 899  HOH B O   1 
HETATM 15301 O O   . HOH J 3 .   ? 14.676  -4.988  -24.662  1.00 22.93  ? 900  HOH B O   1 
HETATM 15302 O O   . HOH J 3 .   ? 42.801  -5.008  -8.495   1.00 17.42  ? 901  HOH B O   1 
HETATM 15303 O O   . HOH J 3 .   ? 16.307  17.846  -48.493  1.00 40.90  ? 902  HOH B O   1 
HETATM 15304 O O   . HOH J 3 .   ? 6.359   -18.330 4.644    1.00 50.00  ? 903  HOH B O   1 
HETATM 15305 O O   . HOH J 3 .   ? 9.680   21.641  -45.413  1.00 32.75  ? 904  HOH B O   1 
HETATM 15306 O O   . HOH J 3 .   ? 23.438  -22.622 3.902    1.00 56.93  ? 905  HOH B O   1 
HETATM 15307 O O   . HOH J 3 .   ? 34.851  -16.437 -10.369  1.00 35.96  ? 906  HOH B O   1 
HETATM 15308 O O   . HOH J 3 .   ? 4.710   9.006   -9.666   1.00 55.25  ? 907  HOH B O   1 
HETATM 15309 O O   . HOH J 3 .   ? 14.715  12.988  -47.816  1.00 24.69  ? 908  HOH B O   1 
HETATM 15310 O O   . HOH J 3 .   ? 20.760  10.891  -58.314  1.00 42.05  ? 909  HOH B O   1 
HETATM 15311 O O   . HOH J 3 .   ? 32.656  -26.534 -28.535  1.00 40.94  ? 910  HOH B O   1 
HETATM 15312 O O   . HOH J 3 .   ? 43.798  -19.974 -16.957  1.00 40.59  ? 911  HOH B O   1 
HETATM 15313 O O   . HOH J 3 .   ? 27.472  6.264   -0.071   1.00 46.86  ? 912  HOH B O   1 
HETATM 15314 O O   . HOH J 3 .   ? 18.948  20.892  -41.402  1.00 44.84  ? 913  HOH B O   1 
HETATM 15315 O O   . HOH J 3 .   ? 2.776   -27.200 -17.727  1.00 39.33  ? 914  HOH B O   1 
HETATM 15316 O O   . HOH J 3 .   ? 34.050  -10.364 -3.893   1.00 26.92  ? 915  HOH B O   1 
HETATM 15317 O O   . HOH J 3 .   ? 5.242   4.871   -45.576  1.00 37.78  ? 916  HOH B O   1 
HETATM 15318 O O   . HOH J 3 .   ? 48.732  -4.809  -23.803  1.00 30.13  ? 917  HOH B O   1 
HETATM 15319 O O   . HOH J 3 .   ? 21.708  -15.230 -29.337  1.00 18.96  ? 918  HOH B O   1 
HETATM 15320 O O   . HOH J 3 .   ? 40.960  2.535   -11.626  1.00 54.69  ? 919  HOH B O   1 
HETATM 15321 O O   . HOH J 3 .   ? 26.350  -22.886 -7.603   1.00 45.30  ? 920  HOH B O   1 
HETATM 15322 O O   . HOH J 3 .   ? 6.020   10.267  -39.308  1.00 23.64  ? 921  HOH B O   1 
HETATM 15323 O O   . HOH J 3 .   ? 14.933  5.269   -50.241  1.00 35.57  ? 922  HOH B O   1 
HETATM 15324 O O   . HOH J 3 .   ? 12.637  -20.704 1.438    1.00 18.75  ? 923  HOH B O   1 
HETATM 15325 O O   . HOH J 3 .   ? 26.069  -22.280 1.031    1.00 54.57  ? 924  HOH B O   1 
HETATM 15326 O O   . HOH J 3 .   ? 46.743  -12.486 -35.288  1.00 25.49  ? 925  HOH B O   1 
HETATM 15327 O O   . HOH J 3 .   ? 26.870  1.388   -50.841  1.00 17.54  ? 926  HOH B O   1 
HETATM 15328 O O   . HOH J 3 .   ? 23.012  -25.035 1.264    1.00 46.24  ? 927  HOH B O   1 
HETATM 15329 O O   . HOH J 3 .   ? 30.977  4.540   -5.157   1.00 28.96  ? 928  HOH B O   1 
HETATM 15330 O O   . HOH J 3 .   ? 12.514  -13.053 -42.977  1.00 31.42  ? 929  HOH B O   1 
HETATM 15331 O O   . HOH J 3 .   ? 26.353  21.800  -21.922  1.00 54.41  ? 930  HOH B O   1 
HETATM 15332 O O   . HOH J 3 .   ? 45.232  -6.047  -35.544  1.00 46.38  ? 931  HOH B O   1 
HETATM 15333 O O   . HOH J 3 .   ? 44.645  -25.447 -25.554  1.00 47.69  ? 932  HOH B O   1 
HETATM 15334 O O   . HOH J 3 .   ? 11.472  15.034  -7.107   1.00 28.40  ? 933  HOH B O   1 
HETATM 15335 O O   . HOH J 3 .   ? 24.043  -18.792 -35.208  1.00 46.90  ? 934  HOH B O   1 
HETATM 15336 O O   . HOH J 3 .   ? 25.691  19.906  -44.058  1.00 36.53  ? 935  HOH B O   1 
HETATM 15337 O O   . HOH J 3 .   ? 24.667  -22.637 -9.901   1.00 42.19  ? 936  HOH B O   1 
HETATM 15338 O O   . HOH J 3 .   ? 37.425  -4.057  -32.096  1.00 20.51  ? 937  HOH B O   1 
HETATM 15339 O O   . HOH J 3 .   ? 23.812  -6.809  5.864    1.00 49.35  ? 938  HOH B O   1 
HETATM 15340 O O   . HOH J 3 .   ? 6.663   7.117   -21.514  1.00 67.92  ? 939  HOH B O   1 
HETATM 15341 O O   . HOH J 3 .   ? 29.961  -25.211 -12.001  1.00 49.77  ? 940  HOH B O   1 
HETATM 15342 O O   . HOH J 3 .   ? 23.250  23.827  -19.494  1.00 20.83  ? 941  HOH B O   1 
HETATM 15343 O O   . HOH J 3 .   ? 45.410  -12.790 -16.629  1.00 35.14  ? 942  HOH B O   1 
HETATM 15344 O O   . HOH J 3 .   ? 8.673   -1.087  -42.436  1.00 55.66  ? 943  HOH B O   1 
HETATM 15345 O O   . HOH J 3 .   ? 22.707  10.570  3.952    1.00 25.17  ? 944  HOH B O   1 
HETATM 15346 O O   . HOH J 3 .   ? 48.236  -9.991  -25.349  1.00 14.11  ? 945  HOH B O   1 
HETATM 15347 O O   . HOH J 3 .   ? 22.590  -22.371 0.499    1.00 36.34  ? 946  HOH B O   1 
HETATM 15348 O O   . HOH J 3 .   ? 20.562  22.388  -46.236  1.00 52.19  ? 947  HOH B O   1 
HETATM 15349 O O   . HOH J 3 .   ? 36.419  2.050   -9.371   1.00 29.13  ? 948  HOH B O   1 
HETATM 15350 O O   . HOH J 3 .   ? 8.931   -25.121 -1.338   1.00 46.45  ? 949  HOH B O   1 
HETATM 15351 O O   . HOH J 3 .   ? 32.360  2.816   -7.168   1.00 26.22  ? 950  HOH B O   1 
HETATM 15352 O O   . HOH J 3 .   ? 14.819  15.551  -48.052  1.00 19.25  ? 951  HOH B O   1 
HETATM 15353 O O   . HOH J 3 .   ? 33.576  -14.727 -7.740   1.00 55.18  ? 952  HOH B O   1 
HETATM 15354 O O   . HOH J 3 .   ? 25.347  18.802  -51.169  1.00 38.05  ? 953  HOH B O   1 
HETATM 15355 O O   . HOH J 3 .   ? 32.445  -4.205  -2.719   1.00 34.59  ? 954  HOH B O   1 
HETATM 15356 O O   . HOH J 3 .   ? 40.554  -10.712 -32.604  1.00 23.82  ? 955  HOH B O   1 
HETATM 15357 O O   . HOH J 3 .   ? 5.621   9.810   -47.319  1.00 20.45  ? 956  HOH B O   1 
HETATM 15358 O O   . HOH J 3 .   ? 30.654  -1.197  -39.782  1.00 41.57  ? 957  HOH B O   1 
HETATM 15359 O O   . HOH J 3 .   ? 10.735  15.237  -18.033  1.00 40.02  ? 958  HOH B O   1 
HETATM 15360 O O   . HOH J 3 .   ? 31.548  8.584   -5.758   1.00 23.54  ? 959  HOH B O   1 
HETATM 15361 O O   . HOH J 3 .   ? -2.034  19.493  -29.064  1.00 40.17  ? 960  HOH B O   1 
HETATM 15362 O O   . HOH J 3 .   ? 27.978  -27.637 -21.126  1.00 42.31  ? 961  HOH B O   1 
HETATM 15363 O O   . HOH J 3 .   ? 26.402  -17.334 -28.663  1.00 31.19  ? 962  HOH B O   1 
HETATM 15364 O O   . HOH J 3 .   ? 22.323  -26.007 6.118    1.00 42.64  ? 963  HOH B O   1 
HETATM 15365 O O   . HOH J 3 .   ? 16.861  -9.260  8.185    1.00 27.82  ? 964  HOH B O   1 
HETATM 15366 O O   . HOH J 3 .   ? 28.857  11.230  -52.511  1.00 30.43  ? 965  HOH B O   1 
HETATM 15367 O O   . HOH J 3 .   ? 13.777  -29.788 -6.280   1.00 59.56  ? 966  HOH B O   1 
HETATM 15368 O O   . HOH J 3 .   ? 12.010  20.778  -43.640  1.00 53.76  ? 967  HOH B O   1 
HETATM 15369 O O   . HOH J 3 .   ? 9.425   -23.870 -23.472  1.00 52.21  ? 968  HOH B O   1 
HETATM 15370 O O   . HOH J 3 .   ? 15.396  -26.588 -7.771   1.00 31.60  ? 969  HOH B O   1 
HETATM 15371 O O   . HOH J 3 .   ? 26.610  -25.893 -33.801  1.00 38.67  ? 970  HOH B O   1 
HETATM 15372 O O   . HOH J 3 .   ? 19.631  8.791   -61.000  1.00 25.52  ? 971  HOH B O   1 
HETATM 15373 O O   . HOH J 3 .   ? 9.680   24.263  -33.739  1.00 52.16  ? 972  HOH B O   1 
HETATM 15374 O O   . HOH J 3 .   ? 23.648  -19.900 0.861    1.00 39.63  ? 973  HOH B O   1 
HETATM 15375 O O   . HOH J 3 .   ? 31.317  -19.272 -4.125   1.00 33.27  ? 974  HOH B O   1 
HETATM 15376 O O   . HOH J 3 .   ? 37.861  6.625   -24.822  1.00 21.25  ? 975  HOH B O   1 
HETATM 15377 O O   . HOH J 3 .   ? 17.191  2.453   6.125    1.00 23.11  ? 976  HOH B O   1 
HETATM 15378 O O   . HOH J 3 .   ? 11.814  -19.177 4.986    1.00 59.01  ? 977  HOH B O   1 
HETATM 15379 O O   . HOH J 3 .   ? 38.243  0.238   -9.438   1.00 28.17  ? 978  HOH B O   1 
HETATM 15380 O O   . HOH J 3 .   ? 8.178   -13.697 -20.791  1.00 43.04  ? 979  HOH B O   1 
HETATM 15381 O O   . HOH J 3 .   ? 45.872  -2.820  -22.902  1.00 21.16  ? 980  HOH B O   1 
HETATM 15382 O O   . HOH J 3 .   ? 10.851  -18.669 2.798    1.00 54.54  ? 981  HOH B O   1 
HETATM 15383 O O   . HOH J 3 .   ? 46.614  2.823   -19.544  1.00 53.83  ? 982  HOH B O   1 
HETATM 15384 O O   . HOH J 3 .   ? 1.888   -23.284 -9.473   1.00 30.29  ? 983  HOH B O   1 
HETATM 15385 O O   . HOH J 3 .   ? 38.564  9.613   -23.355  1.00 31.36  ? 984  HOH B O   1 
HETATM 15386 O O   . HOH J 3 .   ? 8.503   15.848  -18.172  1.00 30.53  ? 985  HOH B O   1 
HETATM 15387 O O   . HOH J 3 .   ? 23.539  2.464   -52.427  1.00 36.24  ? 986  HOH B O   1 
HETATM 15388 O O   . HOH J 3 .   ? 27.326  -3.590  -40.262  1.00 29.09  ? 987  HOH B O   1 
HETATM 15389 O O   . HOH J 3 .   ? 37.744  7.878   -31.278  1.00 36.33  ? 988  HOH B O   1 
HETATM 15390 O O   . HOH J 3 .   ? 22.263  8.574   -54.563  1.00 31.65  ? 989  HOH B O   1 
HETATM 15391 O O   . HOH J 3 .   ? 27.996  -19.365 -37.638  1.00 35.05  ? 990  HOH B O   1 
HETATM 15392 O O   . HOH J 3 .   ? 17.191  19.549  -39.828  1.00 37.02  ? 991  HOH B O   1 
HETATM 15393 O O   . HOH J 3 .   ? 18.969  -13.225 -27.936  1.00 48.26  ? 992  HOH B O   1 
HETATM 15394 O O   . HOH J 3 .   ? -6.429  -14.412 -1.114   1.00 22.09  ? 993  HOH B O   1 
HETATM 15395 O O   . HOH J 3 .   ? 18.546  19.088  -49.927  1.00 28.15  ? 994  HOH B O   1 
HETATM 15396 O O   . HOH J 3 .   ? 38.238  9.739   -29.123  1.00 22.39  ? 995  HOH B O   1 
HETATM 15397 O O   . HOH J 3 .   ? 40.704  7.482   -14.558  1.00 26.13  ? 996  HOH B O   1 
HETATM 15398 O O   . HOH J 3 .   ? 36.169  -11.624 -7.112   1.00 14.18  ? 997  HOH B O   1 
HETATM 15399 O O   . HOH J 3 .   ? 30.283  1.216   -46.661  1.00 43.52  ? 998  HOH B O   1 
HETATM 15400 O O   . HOH J 3 .   ? 25.819  -26.415 -27.370  1.00 40.34  ? 999  HOH B O   1 
HETATM 15401 O O   . HOH J 3 .   ? 40.607  11.486  -26.315  1.00 30.75  ? 1000 HOH B O   1 
HETATM 15402 O O   . HOH J 3 .   ? 15.709  -1.117  -48.158  1.00 23.11  ? 1001 HOH B O   1 
HETATM 15403 O O   . HOH J 3 .   ? 22.004  -2.523  3.785    1.00 53.06  ? 1002 HOH B O   1 
HETATM 15404 O O   . HOH J 3 .   ? 29.446  15.405  -36.547  1.00 56.79  ? 1003 HOH B O   1 
HETATM 15405 O O   . HOH J 3 .   ? 24.606  -5.723  -38.581  1.00 42.77  ? 1004 HOH B O   1 
HETATM 15406 O O   . HOH J 3 .   ? 24.062  -16.345 -28.783  1.00 24.78  ? 1005 HOH B O   1 
HETATM 15407 O O   . HOH J 3 .   ? 19.077  -27.329 6.582    1.00 40.97  ? 1006 HOH B O   1 
HETATM 15408 O O   . HOH J 3 .   ? 40.513  -19.044 -13.894  1.00 41.81  ? 1007 HOH B O   1 
HETATM 15409 O O   . HOH J 3 .   ? 14.188  1.849   -48.440  1.00 15.58  ? 1008 HOH B O   1 
HETATM 15410 O O   . HOH J 3 .   ? 16.612  -12.362 -37.951  1.00 22.87  ? 1009 HOH B O   1 
HETATM 15411 O O   . HOH J 3 .   ? 12.978  -25.454 4.695    1.00 58.27  ? 1010 HOH B O   1 
HETATM 15412 O O   . HOH J 3 .   ? 23.901  -19.242 4.936    1.00 17.48  ? 1011 HOH B O   1 
HETATM 15413 O O   . HOH J 3 .   ? 30.210  -14.127 -1.320   1.00 52.95  ? 1012 HOH B O   1 
HETATM 15414 O O   . HOH J 3 .   ? 31.338  6.889   -33.640  1.00 30.55  ? 1013 HOH B O   1 
HETATM 15415 O O   . HOH J 3 .   ? 21.694  -19.076 -25.754  1.00 38.08  ? 1014 HOH B O   1 
HETATM 15416 O O   . HOH J 3 .   ? 21.921  24.962  -25.324  1.00 38.82  ? 1015 HOH B O   1 
HETATM 15417 O O   . HOH J 3 .   ? 4.735   2.121   -45.835  1.00 11.72  ? 1016 HOH B O   1 
HETATM 15418 O O   . HOH J 3 .   ? 19.654  -7.951  -36.995  1.00 36.09  ? 1017 HOH B O   1 
HETATM 15419 O O   . HOH J 3 .   ? 6.158   6.027   -23.698  1.00 64.85  ? 1018 HOH B O   1 
HETATM 15420 O O   . HOH J 3 .   ? 48.535  -10.462 -22.984  1.00 28.07  ? 1019 HOH B O   1 
HETATM 15421 O O   . HOH J 3 .   ? 15.335  14.810  -56.028  1.00 41.05  ? 1020 HOH B O   1 
HETATM 15422 O O   . HOH J 3 .   ? 33.240  19.348  -44.204  1.00 35.29  ? 1021 HOH B O   1 
HETATM 15423 O O   . HOH J 3 .   ? 20.129  -28.243 -8.944   1.00 25.44  ? 1022 HOH B O   1 
HETATM 15424 O O   . HOH J 3 .   ? 26.385  19.428  -34.706  1.00 49.53  ? 1023 HOH B O   1 
HETATM 15425 O O   . HOH J 3 .   ? 44.227  -21.856 -18.283  1.00 42.24  ? 1024 HOH B O   1 
HETATM 15426 O O   . HOH J 3 .   ? 6.850   -14.616 -38.162  1.00 29.11  ? 1025 HOH B O   1 
HETATM 15427 O O   . HOH J 3 .   ? 0.466   21.350  -29.253  1.00 22.77  ? 1026 HOH B O   1 
HETATM 15428 O O   . HOH J 3 .   ? 32.099  14.082  -42.884  1.00 27.71  ? 1027 HOH B O   1 
HETATM 15429 O O   . HOH J 3 .   ? 17.957  6.340   4.894    1.00 28.62  ? 1028 HOH B O   1 
HETATM 15430 O O   . HOH J 3 .   ? 4.902   7.606   -43.738  1.00 44.98  ? 1029 HOH B O   1 
HETATM 15431 O O   . HOH J 3 .   ? 2.821   18.665  -31.855  1.00 32.09  ? 1030 HOH B O   1 
HETATM 15432 O O   . HOH J 3 .   ? 19.034  25.879  -26.741  1.00 50.09  ? 1031 HOH B O   1 
HETATM 15433 O O   . HOH J 3 .   ? 32.440  -27.074 -23.989  1.00 40.80  ? 1032 HOH B O   1 
HETATM 15434 O O   . HOH J 3 .   ? 46.321  -2.077  -24.776  1.00 29.20  ? 1033 HOH B O   1 
HETATM 15435 O O   . HOH J 3 .   ? -1.470  -14.851 4.943    1.00 51.67  ? 1034 HOH B O   1 
HETATM 15436 O O   . HOH J 3 .   ? 45.630  -15.431 -18.259  1.00 29.50  ? 1035 HOH B O   1 
HETATM 15437 O O   . HOH J 3 .   ? 42.806  7.200   -17.646  1.00 24.67  ? 1036 HOH B O   1 
HETATM 15438 O O   . HOH J 3 .   ? 32.359  6.795   -49.459  1.00 18.04  ? 1037 HOH B O   1 
HETATM 15439 O O   . HOH J 3 .   ? 32.458  4.590   -32.950  1.00 60.62  ? 1038 HOH B O   1 
HETATM 15440 O O   . HOH J 3 .   ? 19.709  -15.218 -26.185  1.00 29.87  ? 1039 HOH B O   1 
HETATM 15441 O O   . HOH J 3 .   ? 4.386   14.587  -14.608  1.00 31.19  ? 1040 HOH B O   1 
HETATM 15442 O O   . HOH J 3 .   ? 31.279  7.327   -43.389  1.00 22.56  ? 1041 HOH B O   1 
HETATM 15443 O O   . HOH J 3 .   ? 44.519  3.524   -21.415  1.00 39.21  ? 1042 HOH B O   1 
HETATM 15444 O O   . HOH J 3 .   ? 5.390   17.313  -14.396  1.00 31.65  ? 1043 HOH B O   1 
HETATM 15445 O O   . HOH J 3 .   ? 1.919   -7.673  -42.805  1.00 30.84  ? 1044 HOH B O   1 
HETATM 15446 O O   . HOH J 3 .   ? 17.248  21.976  -34.975  1.00 36.66  ? 1045 HOH B O   1 
HETATM 15447 O O   . HOH J 3 .   ? 45.444  -3.039  -27.087  1.00 41.86  ? 1046 HOH B O   1 
HETATM 15448 O O   . HOH J 3 .   ? 27.367  -13.440 0.044    1.00 25.91  ? 1047 HOH B O   1 
HETATM 15449 O O   . HOH J 3 .   ? 18.581  12.637  -61.269  1.00 33.29  ? 1048 HOH B O   1 
HETATM 15450 O O   . HOH J 3 .   ? 22.074  1.703   -51.506  1.00 23.49  ? 1049 HOH B O   1 
HETATM 15451 O O   . HOH J 3 .   ? 16.779  -28.031 7.780    1.00 33.75  ? 1050 HOH B O   1 
HETATM 15452 O O   . HOH J 3 .   ? 39.115  1.367   -29.073  1.00 27.06  ? 1051 HOH B O   1 
HETATM 15453 O O   . HOH J 3 .   ? 4.632   -14.030 -39.805  1.00 42.85  ? 1052 HOH B O   1 
HETATM 15454 O O   . HOH J 3 .   ? 4.723   -1.815  -42.645  1.00 51.49  ? 1053 HOH B O   1 
HETATM 15455 O O   . HOH J 3 .   ? 35.327  -5.080  -5.369   1.00 26.53  ? 1054 HOH B O   1 
HETATM 15456 O O   . HOH J 3 .   ? 35.240  1.013   -7.696   1.00 44.05  ? 1055 HOH B O   1 
HETATM 15457 O O   . HOH J 3 .   ? 34.491  10.490  -43.404  1.00 17.51  ? 1056 HOH B O   1 
HETATM 15458 O O   . HOH J 3 .   ? 44.993  -22.453 -20.645  1.00 58.67  ? 1057 HOH B O   1 
HETATM 15459 O O   . HOH J 3 .   ? 9.790   -14.285 -38.057  1.00 39.41  ? 1058 HOH B O   1 
HETATM 15460 O O   . HOH J 3 .   ? 34.186  -2.905  -3.741   1.00 27.43  ? 1059 HOH B O   1 
HETATM 15461 O O   . HOH J 3 .   ? 3.679   13.494  -47.420  1.00 50.84  ? 1060 HOH B O   1 
HETATM 15462 O O   . HOH J 3 .   ? -0.075  -17.118 5.041    1.00 33.99  ? 1061 HOH B O   1 
HETATM 15463 O O   . HOH J 3 .   ? 12.193  -22.334 3.649    1.00 25.04  ? 1062 HOH B O   1 
HETATM 15464 O O   . HOH J 3 .   ? 34.610  12.076  -16.542  1.00 31.70  ? 1063 HOH B O   1 
HETATM 15465 O O   . HOH J 3 .   ? 5.046   -10.255 -42.727  1.00 46.88  ? 1064 HOH B O   1 
HETATM 15466 O O   . HOH J 3 .   ? -8.050  -18.402 -2.991   1.00 34.50  ? 1065 HOH B O   1 
HETATM 15467 O O   . HOH J 3 .   ? 22.057  -30.034 -9.880   1.00 30.67  ? 1066 HOH B O   1 
HETATM 15468 O O   . HOH J 3 .   ? 19.220  23.289  -33.233  1.00 32.41  ? 1067 HOH B O   1 
HETATM 15469 O O   . HOH J 3 .   ? 32.898  3.568   -46.055  1.00 31.96  ? 1068 HOH B O   1 
HETATM 15470 O O   . HOH J 3 .   ? 35.987  -2.383  -5.957   1.00 21.32  ? 1069 HOH B O   1 
HETATM 15471 O O   . HOH J 3 .   ? 39.580  -29.739 -19.828  1.00 41.62  ? 1070 HOH B O   1 
HETATM 15472 O O   . HOH J 3 .   ? 43.240  -24.807 -18.514  1.00 44.22  ? 1071 HOH B O   1 
HETATM 15473 O O   . HOH J 3 .   ? -7.741  -13.804 -3.098   1.00 29.70  ? 1072 HOH B O   1 
HETATM 15474 O O   . HOH J 3 .   ? 30.573  -1.525  -2.458   1.00 23.49  ? 1073 HOH B O   1 
HETATM 15475 O O   . HOH J 3 .   ? 30.500  14.532  -44.976  1.00 36.17  ? 1074 HOH B O   1 
HETATM 15476 O O   . HOH J 3 .   ? 35.264  13.785  -40.207  1.00 21.27  ? 1075 HOH B O   1 
HETATM 15477 O O   . HOH J 3 .   ? 13.280  -28.114 -9.471   1.00 25.34  ? 1076 HOH B O   1 
HETATM 15478 O O   . HOH J 3 .   ? 24.126  10.686  -53.811  1.00 25.97  ? 1077 HOH B O   1 
HETATM 15479 O O   . HOH J 3 .   ? 20.686  -13.303 -36.443  1.00 35.69  ? 1078 HOH B O   1 
HETATM 15480 O O   . HOH J 3 .   ? 33.051  12.617  -18.660  1.00 30.83  ? 1079 HOH B O   1 
HETATM 15481 O O   . HOH J 3 .   ? 10.824  -25.898 3.268    1.00 42.60  ? 1080 HOH B O   1 
HETATM 15482 O O   . HOH J 3 .   ? 4.160   -4.886  -43.019  1.00 38.53  ? 1081 HOH B O   1 
HETATM 15483 O O   . HOH J 3 .   ? 35.864  -4.027  -34.078  1.00 47.32  ? 1082 HOH B O   1 
HETATM 15484 O O   . HOH J 3 .   ? 33.084  7.700   -52.069  1.00 42.29  ? 1083 HOH B O   1 
HETATM 15485 O O   . HOH J 3 .   ? 32.047  17.113  -41.965  1.00 36.92  ? 1084 HOH B O   1 
HETATM 15486 O O   . HOH J 3 .   ? 31.616  4.995   -2.760   1.00 21.91  ? 1085 HOH B O   1 
HETATM 15487 O O   . HOH J 3 .   ? 37.867  -16.349 -10.713  1.00 40.21  ? 1086 HOH B O   1 
HETATM 15488 O O   . HOH J 3 .   ? 32.590  2.244   -4.187   1.00 26.93  ? 1087 HOH B O   1 
HETATM 15489 O O   . HOH J 3 .   ? 37.891  -5.701  -4.717   1.00 44.33  ? 1088 HOH B O   1 
HETATM 15490 O O   . HOH J 3 .   ? 34.124  -27.360 -33.200  1.00 35.01  ? 1089 HOH B O   1 
HETATM 15491 O O   . HOH J 3 .   ? 30.477  7.162   -0.649   1.00 28.99  ? 1090 HOH B O   1 
HETATM 15492 O O   . HOH J 3 .   ? 7.325   -15.694 -33.682  1.00 26.37  ? 1091 HOH B O   1 
HETATM 15493 O O   . HOH J 3 .   ? 45.562  -10.032 -18.201  1.00 31.30  ? 1092 HOH B O   1 
HETATM 15494 O O   . HOH J 3 .   ? 40.324  7.027   -40.721  1.00 41.99  ? 1093 HOH B O   1 
HETATM 15495 O O   . HOH J 3 .   ? 32.441  9.516   -45.072  1.00 19.07  ? 1094 HOH B O   1 
HETATM 15496 O O   . HOH J 3 .   ? 44.741  -13.885 -36.316  1.00 60.06  ? 1095 HOH B O   1 
HETATM 15497 O O   . HOH J 3 .   ? 30.793  11.579  -45.917  1.00 20.38  ? 1096 HOH B O   1 
HETATM 15498 O O   . HOH J 3 .   ? 4.084   -8.023  -43.323  1.00 22.96  ? 1097 HOH B O   1 
HETATM 15499 O O   . HOH J 3 .   ? 40.848  5.033   -38.970  1.00 20.93  ? 1098 HOH B O   1 
HETATM 15500 O O   . HOH J 3 .   ? 0.818   -3.091  -44.035  1.00 30.43  ? 1099 HOH B O   1 
HETATM 15501 O O   . HOH J 3 .   ? 25.063  17.405  -55.000  1.00 40.78  ? 1100 HOH B O   1 
HETATM 15502 O O   . HOH J 3 .   ? 32.245  -0.208  -2.806   1.00 23.25  ? 1101 HOH B O   1 
HETATM 15503 O O   . HOH J 3 .   ? -1.815  -3.202  -43.176  1.00 39.17  ? 1102 HOH B O   1 
HETATM 15504 O O   . HOH J 3 .   ? 1.043   -9.532  -43.745  1.00 21.63  ? 1103 HOH B O   1 
HETATM 15505 O O   . HOH J 3 .   ? 35.640  0.860   -4.523   1.00 44.81  ? 1104 HOH B O   1 
HETATM 15506 O O   . HOH J 3 .   ? -0.842  -9.140  -43.439  1.00 23.15  ? 1105 HOH B O   1 
HETATM 15507 O O   . HOH J 3 .   ? 7.473   -17.891 -36.156  1.00 30.20  ? 1106 HOH B O   1 
HETATM 15508 O O   . HOH K 3 .   ? 11.027  -1.372  -43.666  1.00 55.94  ? 701  HOH C O   1 
HETATM 15509 O O   . HOH K 3 .   ? 5.613   -16.423 -75.029  1.00 8.90   ? 702  HOH C O   1 
HETATM 15510 O O   . HOH K 3 .   ? -11.139 1.805   -94.300  1.00 19.60  ? 703  HOH C O   1 
HETATM 15511 O O   . HOH K 3 .   ? 13.689  -12.143 -44.504  1.00 44.01  ? 704  HOH C O   1 
HETATM 15512 O O   . HOH K 3 .   ? -6.947  29.083  -82.249  1.00 50.88  ? 705  HOH C O   1 
HETATM 15513 O O   . HOH K 3 .   ? 25.663  -3.875  -66.412  1.00 29.41  ? 706  HOH C O   1 
HETATM 15514 O O   . HOH K 3 .   ? 2.074   17.505  -56.690  1.00 19.02  ? 707  HOH C O   1 
HETATM 15515 O O   . HOH K 3 .   ? 11.071  -2.532  -78.583  1.00 14.65  ? 708  HOH C O   1 
HETATM 15516 O O   . HOH K 3 .   ? -1.345  3.474   -72.655  1.00 44.41  ? 709  HOH C O   1 
HETATM 15517 O O   . HOH K 3 .   ? -9.543  -8.387  -57.186  1.00 19.53  ? 710  HOH C O   1 
HETATM 15518 O O   . HOH K 3 .   ? 23.608  9.238   -76.998  1.00 20.25  ? 711  HOH C O   1 
HETATM 15519 O O   . HOH K 3 .   ? -13.064 -1.327  -93.921  1.00 33.05  ? 712  HOH C O   1 
HETATM 15520 O O   . HOH K 3 .   ? 14.274  9.736   -101.132 1.00 56.94  ? 713  HOH C O   1 
HETATM 15521 O O   . HOH K 3 .   ? 12.088  -14.665 -59.071  1.00 24.61  ? 714  HOH C O   1 
HETATM 15522 O O   . HOH K 3 .   ? -18.140 25.440  -83.818  1.00 54.14  ? 715  HOH C O   1 
HETATM 15523 O O   . HOH K 3 .   ? 22.392  -4.760  -47.395  1.00 22.87  ? 716  HOH C O   1 
HETATM 15524 O O   . HOH K 3 .   ? 20.929  5.585   -61.229  1.00 38.94  ? 717  HOH C O   1 
HETATM 15525 O O   . HOH K 3 .   ? -12.006 -13.886 -65.892  1.00 63.44  ? 718  HOH C O   1 
HETATM 15526 O O   . HOH K 3 .   ? -16.972 -12.450 -73.660  1.00 32.46  ? 719  HOH C O   1 
HETATM 15527 O O   . HOH K 3 .   ? 20.722  -11.024 -46.261  1.00 24.79  ? 720  HOH C O   1 
HETATM 15528 O O   . HOH K 3 .   ? 21.938  31.406  -84.841  1.00 42.70  ? 721  HOH C O   1 
HETATM 15529 O O   . HOH K 3 .   ? 17.055  29.394  -87.796  1.00 40.89  ? 722  HOH C O   1 
HETATM 15530 O O   . HOH K 3 .   ? 0.740   1.998   -82.879  1.00 7.00   ? 723  HOH C O   1 
HETATM 15531 O O   . HOH K 3 .   ? 6.993   0.541   -93.685  1.00 28.09  ? 724  HOH C O   1 
HETATM 15532 O O   . HOH K 3 .   ? 1.622   30.554  -76.991  1.00 48.50  ? 725  HOH C O   1 
HETATM 15533 O O   . HOH K 3 .   ? 27.236  25.741  -83.871  1.00 55.94  ? 726  HOH C O   1 
HETATM 15534 O O   . HOH K 3 .   ? 20.625  -15.331 -59.377  1.00 29.38  ? 727  HOH C O   1 
HETATM 15535 O O   . HOH K 3 .   ? 1.250   3.958   -47.617  1.00 21.15  ? 728  HOH C O   1 
HETATM 15536 O O   . HOH K 3 .   ? -6.813  -13.232 -69.372  1.00 16.09  ? 729  HOH C O   1 
HETATM 15537 O O   . HOH K 3 .   ? 8.056   -17.470 -49.333  1.00 45.49  ? 730  HOH C O   1 
HETATM 15538 O O   . HOH K 3 .   ? 17.186  7.150   -60.867  1.00 26.04  ? 731  HOH C O   1 
HETATM 15539 O O   . HOH K 3 .   ? 24.724  -4.070  -53.085  1.00 18.76  ? 732  HOH C O   1 
HETATM 15540 O O   . HOH K 3 .   ? -10.257 -3.855  -63.634  1.00 36.68  ? 733  HOH C O   1 
HETATM 15541 O O   . HOH K 3 .   ? 20.733  4.263   -89.941  1.00 24.88  ? 734  HOH C O   1 
HETATM 15542 O O   . HOH K 3 .   ? -0.314  -6.146  -92.459  1.00 55.84  ? 735  HOH C O   1 
HETATM 15543 O O   . HOH K 3 .   ? 9.182   -8.579  -89.165  1.00 10.99  ? 736  HOH C O   1 
HETATM 15544 O O   . HOH K 3 .   ? 4.541   -20.283 -68.063  1.00 31.86  ? 737  HOH C O   1 
HETATM 15545 O O   . HOH K 3 .   ? 3.687   11.067  -93.859  1.00 28.36  ? 738  HOH C O   1 
HETATM 15546 O O   . HOH K 3 .   ? 21.056  -13.909 -51.526  1.00 30.78  ? 739  HOH C O   1 
HETATM 15547 O O   . HOH K 3 .   ? 17.745  -9.522  -39.244  1.00 30.93  ? 740  HOH C O   1 
HETATM 15548 O O   . HOH K 3 .   ? -6.223  25.084  -85.357  1.00 33.75  ? 741  HOH C O   1 
HETATM 15549 O O   . HOH K 3 .   ? 18.953  -0.191  -59.714  1.00 11.28  ? 742  HOH C O   1 
HETATM 15550 O O   . HOH K 3 .   ? -1.170  -15.405 -74.106  1.00 18.38  ? 743  HOH C O   1 
HETATM 15551 O O   . HOH K 3 .   ? -18.015 -0.940  -89.723  1.00 13.91  ? 744  HOH C O   1 
HETATM 15552 O O   . HOH K 3 .   ? -8.227  -18.145 -58.495  1.00 25.64  ? 745  HOH C O   1 
HETATM 15553 O O   . HOH K 3 .   ? -7.290  -5.078  -91.504  1.00 29.97  ? 746  HOH C O   1 
HETATM 15554 O O   . HOH K 3 .   ? -0.646  7.636   -67.625  1.00 14.86  ? 747  HOH C O   1 
HETATM 15555 O O   . HOH K 3 .   ? 3.176   21.909  -92.977  1.00 53.97  ? 748  HOH C O   1 
HETATM 15556 O O   . HOH K 3 .   ? 15.905  2.434   -93.348  1.00 67.96  ? 749  HOH C O   1 
HETATM 15557 O O   . HOH K 3 .   ? 24.573  -8.689  -66.777  1.00 8.53   ? 750  HOH C O   1 
HETATM 15558 O O   . HOH K 3 .   ? 21.915  -1.346  -84.386  1.00 20.81  ? 751  HOH C O   1 
HETATM 15559 O O   . HOH K 3 .   ? 15.311  0.008   -92.640  1.00 21.12  ? 752  HOH C O   1 
HETATM 15560 O O   . HOH K 3 .   ? -22.607 18.132  -90.326  1.00 47.53  ? 753  HOH C O   1 
HETATM 15561 O O   . HOH K 3 .   ? 4.622   7.069   -82.100  1.00 77.40  ? 754  HOH C O   1 
HETATM 15562 O O   . HOH K 3 .   ? 0.415   -14.789 -46.276  1.00 38.49  ? 755  HOH C O   1 
HETATM 15563 O O   . HOH K 3 .   ? -7.901  21.104  -91.545  1.00 44.87  ? 756  HOH C O   1 
HETATM 15564 O O   . HOH K 3 .   ? 7.050   -17.659 -76.218  1.00 34.00  ? 757  HOH C O   1 
HETATM 15565 O O   . HOH K 3 .   ? 6.523   -4.329  -46.674  1.00 24.60  ? 758  HOH C O   1 
HETATM 15566 O O   . HOH K 3 .   ? 20.478  -3.177  -69.547  1.00 27.80  ? 759  HOH C O   1 
HETATM 15567 O O   . HOH K 3 .   ? 7.369   -16.905 -63.540  1.00 25.91  ? 760  HOH C O   1 
HETATM 15568 O O   . HOH K 3 .   ? 12.342  20.491  -92.431  1.00 24.48  ? 761  HOH C O   1 
HETATM 15569 O O   . HOH K 3 .   ? 8.724   -12.881 -45.628  1.00 33.77  ? 762  HOH C O   1 
HETATM 15570 O O   . HOH K 3 .   ? -2.895  4.243   -86.952  1.00 7.77   ? 763  HOH C O   1 
HETATM 15571 O O   . HOH K 3 .   ? 21.128  -4.970  -86.138  1.00 50.32  ? 764  HOH C O   1 
HETATM 15572 O O   . HOH K 3 .   ? 18.684  2.854   -82.879  1.00 28.58  ? 765  HOH C O   1 
HETATM 15573 O O   . HOH K 3 .   ? -11.932 32.462  -83.617  1.00 52.82  ? 766  HOH C O   1 
HETATM 15574 O O   . HOH K 3 .   ? -14.837 -13.354 -72.339  1.00 17.86  ? 767  HOH C O   1 
HETATM 15575 O O   . HOH K 3 .   ? 3.183   -3.933  -49.395  1.00 15.88  ? 768  HOH C O   1 
HETATM 15576 O O   . HOH K 3 .   ? 26.642  12.912  -84.905  1.00 27.15  ? 769  HOH C O   1 
HETATM 15577 O O   . HOH K 3 .   ? 10.766  1.099   -61.943  1.00 7.57   ? 770  HOH C O   1 
HETATM 15578 O O   . HOH K 3 .   ? 6.569   20.235  -74.199  1.00 21.88  ? 771  HOH C O   1 
HETATM 15579 O O   . HOH K 3 .   ? 6.288   24.172  -70.125  1.00 39.70  ? 772  HOH C O   1 
HETATM 15580 O O   . HOH K 3 .   ? 15.167  19.883  -97.389  1.00 40.94  ? 773  HOH C O   1 
HETATM 15581 O O   . HOH K 3 .   ? 8.583   -16.138 -54.098  1.00 33.91  ? 774  HOH C O   1 
HETATM 15582 O O   . HOH K 3 .   ? 15.945  -11.622 -77.463  1.00 61.13  ? 775  HOH C O   1 
HETATM 15583 O O   . HOH K 3 .   ? 7.149   -9.349  -44.713  1.00 17.84  ? 776  HOH C O   1 
HETATM 15584 O O   . HOH K 3 .   ? -16.238 32.431  -87.335  1.00 60.08  ? 777  HOH C O   1 
HETATM 15585 O O   . HOH K 3 .   ? -3.931  12.457  -49.712  1.00 23.53  ? 778  HOH C O   1 
HETATM 15586 O O   . HOH K 3 .   ? 2.062   30.099  -70.489  1.00 44.66  ? 779  HOH C O   1 
HETATM 15587 O O   . HOH K 3 .   ? -5.623  -20.939 -59.162  1.00 16.87  ? 780  HOH C O   1 
HETATM 15588 O O   . HOH K 3 .   ? 5.528   4.535   -53.062  1.00 50.53  ? 781  HOH C O   1 
HETATM 15589 O O   . HOH K 3 .   ? 15.853  -13.669 -68.860  1.00 17.02  ? 782  HOH C O   1 
HETATM 15590 O O   . HOH K 3 .   ? 7.831   1.323   -71.370  1.00 16.28  ? 783  HOH C O   1 
HETATM 15591 O O   . HOH K 3 .   ? 7.816   -3.534  -41.293  1.00 35.04  ? 784  HOH C O   1 
HETATM 15592 O O   . HOH K 3 .   ? 20.115  -11.959 -70.580  1.00 35.02  ? 785  HOH C O   1 
HETATM 15593 O O   . HOH K 3 .   ? -8.546  -10.476 -70.525  1.00 21.74  ? 786  HOH C O   1 
HETATM 15594 O O   . HOH K 3 .   ? -12.972 -9.469  -77.911  1.00 19.60  ? 787  HOH C O   1 
HETATM 15595 O O   . HOH K 3 .   ? 17.792  -2.137  -89.582  1.00 31.40  ? 788  HOH C O   1 
HETATM 15596 O O   . HOH K 3 .   ? -16.753 -11.442 -80.887  1.00 21.11  ? 789  HOH C O   1 
HETATM 15597 O O   . HOH K 3 .   ? 10.378  -7.105  -87.242  1.00 29.11  ? 790  HOH C O   1 
HETATM 15598 O O   . HOH K 3 .   ? 6.316   5.308   -94.526  1.00 26.98  ? 791  HOH C O   1 
HETATM 15599 O O   . HOH K 3 .   ? 24.423  -0.021  -51.628  1.00 21.58  ? 792  HOH C O   1 
HETATM 15600 O O   . HOH K 3 .   ? 12.125  9.631   -59.070  1.00 32.44  ? 793  HOH C O   1 
HETATM 15601 O O   . HOH K 3 .   ? 5.999   0.560   -44.998  1.00 16.37  ? 794  HOH C O   1 
HETATM 15602 O O   . HOH K 3 .   ? -8.921  -3.923  -74.045  1.00 8.83   ? 795  HOH C O   1 
HETATM 15603 O O   . HOH K 3 .   ? 10.264  7.233   -66.978  1.00 18.23  ? 796  HOH C O   1 
HETATM 15604 O O   . HOH K 3 .   ? 19.611  1.058   -52.212  1.00 27.10  ? 797  HOH C O   1 
HETATM 15605 O O   . HOH K 3 .   ? 22.551  -9.981  -60.538  1.00 13.57  ? 798  HOH C O   1 
HETATM 15606 O O   . HOH K 3 .   ? -9.393  -12.143 -65.752  1.00 51.70  ? 799  HOH C O   1 
HETATM 15607 O O   . HOH K 3 .   ? -7.958  18.539  -66.686  1.00 65.94  ? 800  HOH C O   1 
HETATM 15608 O O   . HOH K 3 .   ? -3.109  2.227   -79.709  1.00 11.22  ? 801  HOH C O   1 
HETATM 15609 O O   . HOH K 3 .   ? 22.166  19.104  -89.699  1.00 28.04  ? 802  HOH C O   1 
HETATM 15610 O O   . HOH K 3 .   ? 12.313  -11.560 -51.793  1.00 13.58  ? 803  HOH C O   1 
HETATM 15611 O O   . HOH K 3 .   ? 9.480   3.431   -70.846  1.00 11.57  ? 804  HOH C O   1 
HETATM 15612 O O   . HOH K 3 .   ? -14.558 -12.165 -85.487  1.00 22.09  ? 805  HOH C O   1 
HETATM 15613 O O   . HOH K 3 .   ? -10.135 -1.426  -74.751  1.00 10.13  ? 806  HOH C O   1 
HETATM 15614 O O   . HOH K 3 .   ? 24.581  13.810  -77.297  1.00 24.81  ? 807  HOH C O   1 
HETATM 15615 O O   . HOH K 3 .   ? 1.831   -6.297  -51.150  1.00 27.63  ? 808  HOH C O   1 
HETATM 15616 O O   . HOH K 3 .   ? 7.790   6.364   -69.431  1.00 27.21  ? 809  HOH C O   1 
HETATM 15617 O O   . HOH K 3 .   ? -13.681 -7.368  -70.327  1.00 23.51  ? 810  HOH C O   1 
HETATM 15618 O O   . HOH K 3 .   ? 22.768  -15.320 -57.932  1.00 23.16  ? 811  HOH C O   1 
HETATM 15619 O O   . HOH K 3 .   ? 11.347  6.431   -96.151  1.00 16.19  ? 812  HOH C O   1 
HETATM 15620 O O   . HOH K 3 .   ? 1.462   13.266  -81.884  1.00 35.14  ? 813  HOH C O   1 
HETATM 15621 O O   . HOH K 3 .   ? 11.629  2.169   -64.499  1.00 15.56  ? 814  HOH C O   1 
HETATM 15622 O O   . HOH K 3 .   ? -23.092 -4.851  -90.299  1.00 23.82  ? 815  HOH C O   1 
HETATM 15623 O O   . HOH K 3 .   ? -9.965  -8.666  -69.638  1.00 32.59  ? 816  HOH C O   1 
HETATM 15624 O O   . HOH K 3 .   ? 2.402   6.834   -49.020  1.00 18.80  ? 817  HOH C O   1 
HETATM 15625 O O   . HOH K 3 .   ? -18.166 26.197  -86.692  1.00 36.60  ? 818  HOH C O   1 
HETATM 15626 O O   . HOH K 3 .   ? 7.820   -2.208  -45.299  1.00 42.87  ? 819  HOH C O   1 
HETATM 15627 O O   . HOH K 3 .   ? -0.302  11.266  -60.253  1.00 12.91  ? 820  HOH C O   1 
HETATM 15628 O O   . HOH K 3 .   ? -27.539 22.544  -81.631  1.00 34.53  ? 821  HOH C O   1 
HETATM 15629 O O   . HOH K 3 .   ? -2.342  26.307  -85.322  1.00 65.62  ? 822  HOH C O   1 
HETATM 15630 O O   . HOH K 3 .   ? 3.227   19.350  -95.208  1.00 45.00  ? 823  HOH C O   1 
HETATM 15631 O O   . HOH K 3 .   ? 19.424  -5.683  -80.243  1.00 57.12  ? 824  HOH C O   1 
HETATM 15632 O O   . HOH K 3 .   ? -27.173 16.781  -85.406  1.00 60.73  ? 825  HOH C O   1 
HETATM 15633 O O   . HOH K 3 .   ? 13.584  -2.616  -43.928  1.00 29.82  ? 826  HOH C O   1 
HETATM 15634 O O   . HOH K 3 .   ? 0.997   -20.557 -58.833  1.00 32.34  ? 827  HOH C O   1 
HETATM 15635 O O   . HOH K 3 .   ? -4.654  7.097   -86.123  1.00 10.14  ? 828  HOH C O   1 
HETATM 15636 O O   . HOH K 3 .   ? 23.595  -15.989 -56.012  1.00 26.05  ? 829  HOH C O   1 
HETATM 15637 O O   . HOH K 3 .   ? 12.434  21.917  -71.433  1.00 28.38  ? 830  HOH C O   1 
HETATM 15638 O O   . HOH K 3 .   ? 14.205  -14.339 -47.033  1.00 57.52  ? 831  HOH C O   1 
HETATM 15639 O O   . HOH K 3 .   ? -5.910  -4.350  -65.134  1.00 16.00  ? 832  HOH C O   1 
HETATM 15640 O O   . HOH K 3 .   ? 8.262   11.851  -97.249  1.00 22.53  ? 833  HOH C O   1 
HETATM 15641 O O   . HOH K 3 .   ? 8.923   -10.318 -80.733  1.00 35.44  ? 834  HOH C O   1 
HETATM 15642 O O   . HOH K 3 .   ? 3.579   -1.341  -75.228  1.00 14.72  ? 835  HOH C O   1 
HETATM 15643 O O   . HOH K 3 .   ? 0.113   3.724   -84.826  1.00 26.64  ? 836  HOH C O   1 
HETATM 15644 O O   . HOH K 3 .   ? 4.024   0.799   -76.957  1.00 10.81  ? 837  HOH C O   1 
HETATM 15645 O O   . HOH K 3 .   ? 2.905   -22.342 -57.425  1.00 42.15  ? 838  HOH C O   1 
HETATM 15646 O O   . HOH K 3 .   ? -29.839 20.078  -70.835  1.00 59.04  ? 839  HOH C O   1 
HETATM 15647 O O   . HOH K 3 .   ? 28.064  -4.657  -59.607  1.00 41.13  ? 840  HOH C O   1 
HETATM 15648 O O   . HOH K 3 .   ? 23.947  -4.657  -49.684  1.00 29.14  ? 841  HOH C O   1 
HETATM 15649 O O   . HOH K 3 .   ? 18.749  16.140  -92.892  1.00 25.88  ? 842  HOH C O   1 
HETATM 15650 O O   . HOH K 3 .   ? 5.584   -12.667 -44.136  1.00 22.09  ? 843  HOH C O   1 
HETATM 15651 O O   . HOH K 3 .   ? -0.088  22.207  -94.297  1.00 35.87  ? 844  HOH C O   1 
HETATM 15652 O O   . HOH K 3 .   ? 17.434  -5.806  -73.182  1.00 40.01  ? 845  HOH C O   1 
HETATM 15653 O O   . HOH K 3 .   ? 13.345  -17.188 -57.945  1.00 36.66  ? 846  HOH C O   1 
HETATM 15654 O O   . HOH K 3 .   ? 21.936  11.440  -89.967  1.00 34.84  ? 847  HOH C O   1 
HETATM 15655 O O   . HOH K 3 .   ? 25.971  -0.407  -59.374  1.00 17.57  ? 848  HOH C O   1 
HETATM 15656 O O   . HOH K 3 .   ? 20.799  20.506  -91.289  1.00 23.90  ? 849  HOH C O   1 
HETATM 15657 O O   . HOH K 3 .   ? 12.017  -8.196  -82.496  1.00 37.54  ? 850  HOH C O   1 
HETATM 15658 O O   . HOH K 3 .   ? 20.659  7.461   -70.926  1.00 22.48  ? 851  HOH C O   1 
HETATM 15659 O O   . HOH K 3 .   ? -11.974 5.090   -92.374  1.00 6.67   ? 852  HOH C O   1 
HETATM 15660 O O   . HOH K 3 .   ? 18.041  -0.374  -81.868  1.00 21.62  ? 853  HOH C O   1 
HETATM 15661 O O   . HOH K 3 .   ? 23.476  29.261  -84.918  1.00 38.18  ? 854  HOH C O   1 
HETATM 15662 O O   . HOH K 3 .   ? 13.831  -9.151  -50.012  1.00 14.55  ? 855  HOH C O   1 
HETATM 15663 O O   . HOH K 3 .   ? -8.870  0.723   -94.031  1.00 25.78  ? 856  HOH C O   1 
HETATM 15664 O O   . HOH K 3 .   ? 1.701   25.351  -91.520  1.00 38.47  ? 857  HOH C O   1 
HETATM 15665 O O   . HOH K 3 .   ? 18.200  6.705   -81.615  1.00 6.80   ? 858  HOH C O   1 
HETATM 15666 O O   . HOH K 3 .   ? 0.895   9.099   -69.678  1.00 34.03  ? 859  HOH C O   1 
HETATM 15667 O O   . HOH K 3 .   ? -7.746  11.655  -92.398  1.00 23.63  ? 860  HOH C O   1 
HETATM 15668 O O   . HOH K 3 .   ? 5.091   2.874   -50.123  1.00 30.69  ? 861  HOH C O   1 
HETATM 15669 O O   . HOH K 3 .   ? -9.075  -13.643 -62.475  1.00 52.68  ? 862  HOH C O   1 
HETATM 15670 O O   . HOH K 3 .   ? -5.703  4.392   -94.061  1.00 49.42  ? 863  HOH C O   1 
HETATM 15671 O O   . HOH K 3 .   ? -11.641 31.119  -77.319  1.00 53.73  ? 864  HOH C O   1 
HETATM 15672 O O   . HOH K 3 .   ? -0.662  32.943  -70.380  1.00 49.59  ? 865  HOH C O   1 
HETATM 15673 O O   . HOH K 3 .   ? 18.676  31.522  -86.623  1.00 62.60  ? 866  HOH C O   1 
HETATM 15674 O O   . HOH K 3 .   ? 2.568   1.310   -93.030  1.00 34.05  ? 867  HOH C O   1 
HETATM 15675 O O   . HOH K 3 .   ? 24.551  -7.142  -57.508  1.00 17.53  ? 868  HOH C O   1 
HETATM 15676 O O   . HOH K 3 .   ? -1.902  6.564   -66.416  1.00 16.16  ? 869  HOH C O   1 
HETATM 15677 O O   . HOH K 3 .   ? 4.360   17.447  -72.104  1.00 32.06  ? 870  HOH C O   1 
HETATM 15678 O O   . HOH K 3 .   ? 16.724  7.613   -63.401  1.00 23.52  ? 871  HOH C O   1 
HETATM 15679 O O   . HOH K 3 .   ? 6.503   21.089  -81.421  1.00 21.10  ? 872  HOH C O   1 
HETATM 15680 O O   . HOH K 3 .   ? 20.301  4.439   -81.562  1.00 26.28  ? 873  HOH C O   1 
HETATM 15681 O O   . HOH K 3 .   ? 15.052  10.359  -64.675  1.00 41.62  ? 874  HOH C O   1 
HETATM 15682 O O   . HOH K 3 .   ? -11.549 -8.339  -68.048  1.00 29.54  ? 875  HOH C O   1 
HETATM 15683 O O   . HOH K 3 .   ? 7.205   -8.388  -47.076  1.00 11.40  ? 876  HOH C O   1 
HETATM 15684 O O   . HOH K 3 .   ? 9.016   15.528  -58.334  1.00 49.70  ? 877  HOH C O   1 
HETATM 15685 O O   . HOH K 3 .   ? -18.497 29.836  -82.249  1.00 45.64  ? 878  HOH C O   1 
HETATM 15686 O O   . HOH K 3 .   ? 19.078  -17.074 -58.431  1.00 42.88  ? 879  HOH C O   1 
HETATM 15687 O O   . HOH K 3 .   ? 23.077  17.226  -87.897  1.00 28.82  ? 880  HOH C O   1 
HETATM 15688 O O   . HOH K 3 .   ? -3.246  -25.212 -67.841  1.00 35.93  ? 881  HOH C O   1 
HETATM 15689 O O   . HOH K 3 .   ? 2.058   -9.054  -51.767  1.00 11.17  ? 882  HOH C O   1 
HETATM 15690 O O   . HOH K 3 .   ? 17.190  -4.720  -84.614  1.00 23.50  ? 883  HOH C O   1 
HETATM 15691 O O   . HOH K 3 .   ? 5.376   -21.173 -65.763  1.00 18.94  ? 884  HOH C O   1 
HETATM 15692 O O   . HOH K 3 .   ? -0.124  -0.098  -93.540  1.00 44.43  ? 885  HOH C O   1 
HETATM 15693 O O   . HOH K 3 .   ? 20.215  -8.573  -79.264  1.00 19.66  ? 886  HOH C O   1 
HETATM 15694 O O   . HOH K 3 .   ? 6.086   2.708   -78.577  1.00 13.33  ? 887  HOH C O   1 
HETATM 15695 O O   . HOH K 3 .   ? 14.111  -0.782  -46.122  1.00 25.97  ? 888  HOH C O   1 
HETATM 15696 O O   . HOH K 3 .   ? 13.829  -11.895 -74.699  1.00 52.47  ? 889  HOH C O   1 
HETATM 15697 O O   . HOH K 3 .   ? 0.072   -11.214 -93.078  1.00 27.88  ? 890  HOH C O   1 
HETATM 15698 O O   . HOH K 3 .   ? 0.835   -19.259 -56.423  1.00 40.80  ? 891  HOH C O   1 
HETATM 15699 O O   . HOH K 3 .   ? -17.292 -6.219  -64.909  1.00 38.35  ? 892  HOH C O   1 
HETATM 15700 O O   . HOH K 3 .   ? -14.705 -18.921 -58.838  1.00 36.73  ? 893  HOH C O   1 
HETATM 15701 O O   . HOH K 3 .   ? 20.494  -12.717 -48.653  1.00 43.30  ? 894  HOH C O   1 
HETATM 15702 O O   . HOH K 3 .   ? 15.123  -5.846  -85.548  1.00 20.61  ? 895  HOH C O   1 
HETATM 15703 O O   . HOH K 3 .   ? 15.564  -14.450 -50.573  1.00 33.87  ? 896  HOH C O   1 
HETATM 15704 O O   . HOH K 3 .   ? 21.994  7.273   -76.256  1.00 17.46  ? 897  HOH C O   1 
HETATM 15705 O O   . HOH K 3 .   ? 13.997  -11.744 -49.654  1.00 25.78  ? 898  HOH C O   1 
HETATM 15706 O O   . HOH K 3 .   ? -2.967  8.844   -92.700  1.00 12.35  ? 899  HOH C O   1 
HETATM 15707 O O   . HOH K 3 .   ? 23.256  -9.448  -50.981  1.00 47.29  ? 900  HOH C O   1 
HETATM 15708 O O   . HOH K 3 .   ? 10.183  -18.055 -66.362  1.00 44.04  ? 901  HOH C O   1 
HETATM 15709 O O   . HOH K 3 .   ? -0.422  27.493  -85.161  1.00 63.26  ? 902  HOH C O   1 
HETATM 15710 O O   . HOH K 3 .   ? 25.578  1.747   -55.452  1.00 24.23  ? 903  HOH C O   1 
HETATM 15711 O O   . HOH K 3 .   ? 21.252  -0.005  -88.092  1.00 35.12  ? 904  HOH C O   1 
HETATM 15712 O O   . HOH K 3 .   ? 5.883   20.137  -91.855  1.00 41.14  ? 905  HOH C O   1 
HETATM 15713 O O   . HOH K 3 .   ? -1.748  -23.250 -78.051  1.00 40.24  ? 906  HOH C O   1 
HETATM 15714 O O   . HOH K 3 .   ? 8.149   3.828   -93.753  1.00 38.20  ? 907  HOH C O   1 
HETATM 15715 O O   . HOH K 3 .   ? -4.957  -18.208 -56.074  1.00 31.02  ? 908  HOH C O   1 
HETATM 15716 O O   . HOH K 3 .   ? -5.591  9.978   -93.180  1.00 24.70  ? 909  HOH C O   1 
HETATM 15717 O O   . HOH K 3 .   ? 24.079  -15.627 -53.493  1.00 29.86  ? 910  HOH C O   1 
HETATM 15718 O O   . HOH K 3 .   ? 7.070   15.260  -94.999  1.00 55.80  ? 911  HOH C O   1 
HETATM 15719 O O   . HOH K 3 .   ? -8.430  -3.261  -66.344  1.00 51.38  ? 912  HOH C O   1 
HETATM 15720 O O   . HOH K 3 .   ? -17.530 -5.046  -73.243  1.00 34.12  ? 913  HOH C O   1 
HETATM 15721 O O   . HOH K 3 .   ? 26.092  -6.770  -70.906  1.00 31.90  ? 914  HOH C O   1 
HETATM 15722 O O   . HOH K 3 .   ? -3.264  -15.615 -52.831  1.00 31.27  ? 915  HOH C O   1 
HETATM 15723 O O   . HOH K 3 .   ? 26.514  3.625   -58.429  1.00 28.98  ? 916  HOH C O   1 
HETATM 15724 O O   . HOH K 3 .   ? -13.938 -10.989 -80.020  1.00 11.68  ? 917  HOH C O   1 
HETATM 15725 O O   . HOH K 3 .   ? 10.027  4.374   -94.982  1.00 26.08  ? 918  HOH C O   1 
HETATM 15726 O O   . HOH K 3 .   ? -1.519  -20.559 -58.428  1.00 41.64  ? 919  HOH C O   1 
HETATM 15727 O O   . HOH K 3 .   ? -1.966  -17.810 -54.937  1.00 38.59  ? 920  HOH C O   1 
HETATM 15728 O O   . HOH K 3 .   ? -9.676  -7.403  -91.173  1.00 27.54  ? 921  HOH C O   1 
HETATM 15729 O O   . HOH K 3 .   ? 25.547  11.552  -76.830  1.00 53.80  ? 922  HOH C O   1 
HETATM 15730 O O   . HOH K 3 .   ? -10.064 22.296  -92.094  1.00 40.45  ? 923  HOH C O   1 
HETATM 15731 O O   . HOH K 3 .   ? 10.768  -15.829 -57.640  1.00 46.59  ? 924  HOH C O   1 
HETATM 15732 O O   . HOH K 3 .   ? -11.111 -16.546 -54.835  1.00 16.87  ? 925  HOH C O   1 
HETATM 15733 O O   . HOH K 3 .   ? 24.280  -2.237  -62.814  1.00 25.08  ? 926  HOH C O   1 
HETATM 15734 O O   . HOH K 3 .   ? -2.247  -7.236  -93.935  1.00 26.93  ? 927  HOH C O   1 
HETATM 15735 O O   . HOH K 3 .   ? 7.556   -17.810 -78.346  1.00 38.41  ? 928  HOH C O   1 
HETATM 15736 O O   . HOH K 3 .   ? 0.773   7.884   -96.037  1.00 28.47  ? 929  HOH C O   1 
HETATM 15737 O O   . HOH K 3 .   ? -2.991  6.717   -93.892  1.00 23.12  ? 930  HOH C O   1 
HETATM 15738 O O   . HOH K 3 .   ? 4.308   9.203   -95.124  1.00 34.13  ? 931  HOH C O   1 
HETATM 15739 O O   . HOH K 3 .   ? 23.359  8.727   -89.647  1.00 45.35  ? 932  HOH C O   1 
HETATM 15740 O O   . HOH K 3 .   ? 9.109   11.222  -99.595  1.00 35.47  ? 933  HOH C O   1 
HETATM 15741 O O   . HOH K 3 .   ? 19.625  -18.130 -53.668  1.00 44.84  ? 934  HOH C O   1 
HETATM 15742 O O   . HOH K 3 .   ? -8.740  25.407  -92.979  1.00 43.60  ? 935  HOH C O   1 
HETATM 15743 O O   . HOH K 3 .   ? -16.142 -14.661 -57.478  1.00 35.10  ? 936  HOH C O   1 
HETATM 15744 O O   . HOH K 3 .   ? -15.816 -2.766  -93.391  1.00 25.25  ? 937  HOH C O   1 
HETATM 15745 O O   . HOH K 3 .   ? -31.252 18.470  -72.884  1.00 16.78  ? 938  HOH C O   1 
HETATM 15746 O O   . HOH K 3 .   ? 4.798   22.159  -78.329  1.00 24.96  ? 939  HOH C O   1 
HETATM 15747 O O   . HOH K 3 .   ? -9.697  30.370  -81.389  1.00 44.05  ? 940  HOH C O   1 
HETATM 15748 O O   . HOH K 3 .   ? 23.088  6.006   -58.429  1.00 20.81  ? 941  HOH C O   1 
HETATM 15749 O O   . HOH K 3 .   ? 10.537  20.737  -71.271  1.00 23.98  ? 942  HOH C O   1 
HETATM 15750 O O   . HOH K 3 .   ? 19.801  -13.718 -66.363  1.00 33.39  ? 943  HOH C O   1 
HETATM 15751 O O   . HOH K 3 .   ? 19.726  -16.690 -61.838  1.00 48.27  ? 944  HOH C O   1 
HETATM 15752 O O   . HOH K 3 .   ? -6.027  10.970  -95.438  1.00 24.07  ? 945  HOH C O   1 
HETATM 15753 O O   . HOH K 3 .   ? -6.989  -3.054  -63.310  1.00 59.50  ? 946  HOH C O   1 
HETATM 15754 O O   . HOH K 3 .   ? 14.567  -1.427  -49.363  1.00 32.65  ? 947  HOH C O   1 
HETATM 15755 O O   . HOH K 3 .   ? 2.882   -24.092 -63.463  1.00 37.99  ? 948  HOH C O   1 
HETATM 15756 O O   . HOH K 3 .   ? -3.336  -15.306 -50.234  1.00 29.79  ? 949  HOH C O   1 
HETATM 15757 O O   . HOH K 3 .   ? 9.156   -4.758  -95.705  1.00 44.40  ? 950  HOH C O   1 
HETATM 15758 O O   . HOH K 3 .   ? 17.995  -3.465  -82.549  1.00 31.36  ? 951  HOH C O   1 
HETATM 15759 O O   . HOH K 3 .   ? 0.611   -18.092 -45.748  1.00 37.49  ? 952  HOH C O   1 
HETATM 15760 O O   . HOH K 3 .   ? -12.742 28.568  -96.686  1.00 41.76  ? 953  HOH C O   1 
HETATM 15761 O O   . HOH K 3 .   ? 5.776   17.721  -54.877  1.00 51.91  ? 954  HOH C O   1 
HETATM 15762 O O   . HOH K 3 .   ? 5.899   18.490  -62.862  1.00 43.85  ? 955  HOH C O   1 
HETATM 15763 O O   . HOH K 3 .   ? 5.362   -20.888 -72.123  1.00 42.46  ? 956  HOH C O   1 
HETATM 15764 O O   . HOH K 3 .   ? -5.483  31.847  -83.124  1.00 55.78  ? 957  HOH C O   1 
HETATM 15765 O O   . HOH K 3 .   ? 6.249   -6.649  -44.836  1.00 25.58  ? 958  HOH C O   1 
HETATM 15766 O O   . HOH K 3 .   ? 0.078   -24.129 -63.681  1.00 48.56  ? 959  HOH C O   1 
HETATM 15767 O O   . HOH K 3 .   ? 13.667  31.012  -78.255  1.00 36.14  ? 960  HOH C O   1 
HETATM 15768 O O   . HOH K 3 .   ? 13.892  22.936  -92.308  1.00 46.48  ? 961  HOH C O   1 
HETATM 15769 O O   . HOH K 3 .   ? 24.596  -4.026  -64.423  1.00 28.02  ? 962  HOH C O   1 
HETATM 15770 O O   . HOH K 3 .   ? 12.655  -15.574 -76.380  1.00 41.37  ? 963  HOH C O   1 
HETATM 15771 O O   . HOH K 3 .   ? -9.319  -12.399 -69.585  1.00 16.65  ? 964  HOH C O   1 
HETATM 15772 O O   . HOH K 3 .   ? 2.422   -26.026 -66.283  1.00 56.56  ? 965  HOH C O   1 
HETATM 15773 O O   . HOH K 3 .   ? 9.788   -14.750 -79.994  1.00 46.26  ? 966  HOH C O   1 
HETATM 15774 O O   . HOH K 3 .   ? 15.488  -10.245 -80.317  1.00 38.04  ? 967  HOH C O   1 
HETATM 15775 O O   . HOH K 3 .   ? 24.268  -10.608 -64.929  1.00 20.86  ? 968  HOH C O   1 
HETATM 15776 O O   . HOH K 3 .   ? 15.052  -16.313 -49.197  1.00 64.25  ? 969  HOH C O   1 
HETATM 15777 O O   . HOH K 3 .   ? 18.268  -14.306 -50.913  1.00 35.79  ? 970  HOH C O   1 
HETATM 15778 O O   . HOH K 3 .   ? 25.991  -4.509  -42.582  1.00 28.09  ? 971  HOH C O   1 
HETATM 15779 O O   . HOH K 3 .   ? 5.026   -1.600  -45.233  1.00 46.04  ? 972  HOH C O   1 
HETATM 15780 O O   . HOH K 3 .   ? -9.728  28.246  -92.461  1.00 36.90  ? 973  HOH C O   1 
HETATM 15781 O O   . HOH K 3 .   ? 14.913  -18.071 -52.495  1.00 25.33  ? 974  HOH C O   1 
HETATM 15782 O O   . HOH K 3 .   ? 16.984  -1.784  -73.563  1.00 66.37  ? 975  HOH C O   1 
HETATM 15783 O O   . HOH K 3 .   ? 28.940  -2.423  -54.143  1.00 28.72  ? 976  HOH C O   1 
HETATM 15784 O O   . HOH K 3 .   ? -2.770  33.484  -83.997  1.00 52.58  ? 977  HOH C O   1 
HETATM 15785 O O   . HOH K 3 .   ? 5.270   17.959  -69.976  1.00 41.30  ? 978  HOH C O   1 
HETATM 15786 O O   . HOH K 3 .   ? -0.989  33.520  -76.402  1.00 60.61  ? 979  HOH C O   1 
HETATM 15787 O O   . HOH K 3 .   ? -12.537 6.935   -94.850  1.00 31.85  ? 980  HOH C O   1 
HETATM 15788 O O   . HOH K 3 .   ? -17.943 -1.727  -92.546  1.00 28.62  ? 981  HOH C O   1 
HETATM 15789 O O   . HOH K 3 .   ? 19.107  24.644  -91.433  1.00 33.83  ? 982  HOH C O   1 
HETATM 15790 O O   . HOH K 3 .   ? 13.540  3.341   -94.149  1.00 58.89  ? 983  HOH C O   1 
HETATM 15791 O O   . HOH K 3 .   ? 4.400   15.787  -95.666  1.00 40.79  ? 984  HOH C O   1 
HETATM 15792 O O   . HOH K 3 .   ? 23.326  -11.691 -45.954  1.00 33.69  ? 985  HOH C O   1 
HETATM 15793 O O   . HOH K 3 .   ? 1.172   -4.855  -93.733  1.00 6.82   ? 986  HOH C O   1 
HETATM 15794 O O   . HOH K 3 .   ? -8.837  -17.946 -56.015  1.00 26.23  ? 987  HOH C O   1 
HETATM 15795 O O   . HOH K 3 .   ? 18.119  -3.268  -71.701  1.00 47.27  ? 988  HOH C O   1 
HETATM 15796 O O   . HOH K 3 .   ? 4.950   -22.130 -69.734  1.00 35.44  ? 989  HOH C O   1 
HETATM 15797 O O   . HOH K 3 .   ? -13.958 -12.748 -70.421  1.00 29.22  ? 990  HOH C O   1 
HETATM 15798 O O   . HOH K 3 .   ? -19.877 28.798  -87.644  1.00 33.02  ? 991  HOH C O   1 
HETATM 15799 O O   . HOH K 3 .   ? 18.536  -12.647 -68.215  1.00 47.78  ? 992  HOH C O   1 
HETATM 15800 O O   . HOH K 3 .   ? 22.624  27.106  -89.361  1.00 28.62  ? 993  HOH C O   1 
HETATM 15801 O O   . HOH K 3 .   ? 15.390  -15.732 -67.320  1.00 33.50  ? 994  HOH C O   1 
HETATM 15802 O O   . HOH K 3 .   ? 4.095   -23.755 -65.521  1.00 46.94  ? 995  HOH C O   1 
HETATM 15803 O O   . HOH K 3 .   ? 5.108   3.288   -93.934  1.00 38.96  ? 996  HOH C O   1 
HETATM 15804 O O   . HOH K 3 .   ? 1.144   1.493   -95.125  1.00 42.51  ? 997  HOH C O   1 
HETATM 15805 O O   . HOH K 3 .   ? 24.923  -9.581  -69.192  1.00 33.96  ? 998  HOH C O   1 
HETATM 15806 O O   . HOH K 3 .   ? 8.752   -18.731 -51.969  1.00 26.90  ? 999  HOH C O   1 
HETATM 15807 O O   . HOH K 3 .   ? 19.436  0.329   -73.304  1.00 38.86  ? 1000 HOH C O   1 
HETATM 15808 O O   . HOH K 3 .   ? 4.643   17.914  -93.371  1.00 47.97  ? 1001 HOH C O   1 
HETATM 15809 O O   . HOH K 3 .   ? 10.495  -15.382 -47.609  1.00 29.68  ? 1002 HOH C O   1 
HETATM 15810 O O   . HOH K 3 .   ? 3.735   -3.938  -46.981  1.00 17.67  ? 1003 HOH C O   1 
HETATM 15811 O O   . HOH K 3 .   ? 9.921   -16.592 -59.541  1.00 43.01  ? 1004 HOH C O   1 
HETATM 15812 O O   . HOH K 3 .   ? -10.798 -11.294 -67.604  1.00 49.66  ? 1005 HOH C O   1 
HETATM 15813 O O   . HOH K 3 .   ? 16.512  33.331  -86.246  1.00 51.58  ? 1006 HOH C O   1 
HETATM 15814 O O   . HOH K 3 .   ? -12.655 -19.068 -55.122  1.00 52.76  ? 1007 HOH C O   1 
HETATM 15815 O O   . HOH K 3 .   ? 9.123   14.025  -97.526  1.00 39.07  ? 1008 HOH C O   1 
HETATM 15816 O O   . HOH K 3 .   ? 8.086   -19.805 -65.046  1.00 38.67  ? 1009 HOH C O   1 
HETATM 15817 O O   . HOH K 3 .   ? 4.630   6.946   -95.932  1.00 15.18  ? 1010 HOH C O   1 
HETATM 15818 O O   . HOH K 3 .   ? -4.980  -15.271 -54.912  1.00 51.19  ? 1011 HOH C O   1 
HETATM 15819 O O   . HOH K 3 .   ? 24.690  -6.396  -51.069  1.00 27.22  ? 1012 HOH C O   1 
HETATM 15820 O O   . HOH K 3 .   ? 19.348  -12.222 -43.802  1.00 37.26  ? 1013 HOH C O   1 
HETATM 15821 O O   . HOH K 3 .   ? -7.936  3.269   -94.740  1.00 27.92  ? 1014 HOH C O   1 
HETATM 15822 O O   . HOH K 3 .   ? 5.067   10.761  -97.361  1.00 38.56  ? 1015 HOH C O   1 
HETATM 15823 O O   . HOH K 3 .   ? 24.001  -10.489 -44.138  1.00 50.50  ? 1016 HOH C O   1 
HETATM 15824 O O   . HOH K 3 .   ? 32.510  18.248  -83.343  1.00 45.28  ? 1017 HOH C O   1 
HETATM 15825 O O   . HOH K 3 .   ? -1.733  5.871   -95.376  1.00 26.79  ? 1018 HOH C O   1 
HETATM 15826 O O   . HOH K 3 .   ? 32.707  18.240  -80.580  1.00 52.95  ? 1019 HOH C O   1 
HETATM 15827 O O   . HOH K 3 .   ? 3.266   18.328  -53.947  1.00 39.87  ? 1020 HOH C O   1 
HETATM 15828 O O   . HOH K 3 .   ? 22.903  15.234  -89.789  1.00 43.60  ? 1021 HOH C O   1 
HETATM 15829 O O   . HOH K 3 .   ? 5.307   34.825  -82.168  1.00 76.01  ? 1022 HOH C O   1 
HETATM 15830 O O   . HOH K 3 .   ? 20.459  18.419  -92.571  1.00 39.01  ? 1023 HOH C O   1 
HETATM 15831 O O   . HOH K 3 .   ? 11.258  14.776  -99.582  1.00 30.12  ? 1024 HOH C O   1 
HETATM 15832 O O   . HOH K 3 .   ? 3.051   8.786   -47.150  1.00 30.13  ? 1025 HOH C O   1 
HETATM 15833 O O   . HOH K 3 .   ? 10.019  -8.811  -84.495  1.00 25.03  ? 1026 HOH C O   1 
HETATM 15834 O O   . HOH K 3 .   ? 21.985  7.012   -73.567  1.00 36.31  ? 1027 HOH C O   1 
HETATM 15835 O O   . HOH K 3 .   ? 8.917   -10.898 -83.262  1.00 23.04  ? 1028 HOH C O   1 
HETATM 15836 O O   . HOH K 3 .   ? 14.377  22.246  -95.168  1.00 37.86  ? 1029 HOH C O   1 
HETATM 15837 O O   . HOH K 3 .   ? 1.458   11.054  -45.024  1.00 29.12  ? 1030 HOH C O   1 
HETATM 15838 O O   . HOH K 3 .   ? 9.562   20.451  -93.197  1.00 26.60  ? 1031 HOH C O   1 
HETATM 15839 O O   . HOH K 3 .   ? -30.913 16.787  -70.676  1.00 34.07  ? 1032 HOH C O   1 
HETATM 15840 O O   . HOH K 3 .   ? -17.837 -17.230 -57.190  1.00 64.94  ? 1033 HOH C O   1 
HETATM 15841 O O   . HOH K 3 .   ? 2.931   -2.115  -44.575  1.00 68.39  ? 1034 HOH C O   1 
HETATM 15842 O O   . HOH K 3 .   ? 17.642  1.385   -50.003  1.00 16.93  ? 1035 HOH C O   1 
HETATM 15843 O O   . HOH K 3 .   ? 21.057  -18.262 -56.340  1.00 35.82  ? 1036 HOH C O   1 
HETATM 15844 O O   . HOH K 3 .   ? -14.868 -24.527 -58.985  1.00 49.27  ? 1037 HOH C O   1 
HETATM 15845 O O   . HOH K 3 .   ? 1.381   3.722   -44.995  1.00 41.53  ? 1038 HOH C O   1 
HETATM 15846 O O   . HOH K 3 .   ? -0.186  19.457  -56.306  1.00 34.35  ? 1039 HOH C O   1 
HETATM 15847 O O   . HOH K 3 .   ? -2.155  9.833   -43.318  1.00 26.95  ? 1040 HOH C O   1 
HETATM 15848 O O   . HOH K 3 .   ? 20.472  13.916  -92.008  1.00 22.30  ? 1041 HOH C O   1 
HETATM 15849 O O   . HOH K 3 .   ? 19.466  8.785   -64.350  1.00 28.21  ? 1042 HOH C O   1 
HETATM 15850 O O   . HOH K 3 .   ? -1.071  -11.525 -44.743  1.00 28.23  ? 1043 HOH C O   1 
HETATM 15851 O O   . HOH K 3 .   ? -0.045  0.263   -43.938  1.00 25.49  ? 1044 HOH C O   1 
HETATM 15852 O O   . HOH K 3 .   ? -0.094  4.076   -96.018  1.00 27.26  ? 1045 HOH C O   1 
HETATM 15853 O O   . HOH K 3 .   ? 2.263   5.182   -96.656  1.00 48.68  ? 1046 HOH C O   1 
HETATM 15854 O O   . HOH K 3 .   ? 29.237  34.103  -76.512  1.00 49.59  ? 1047 HOH C O   1 
HETATM 15855 O O   . HOH K 3 .   ? 10.458  17.034  -98.892  1.00 20.64  ? 1048 HOH C O   1 
HETATM 15856 O O   . HOH L 3 .   ? -9.938  -13.827 -53.010  1.00 19.68  ? 701  HOH D O   1 
HETATM 15857 O O   . HOH L 3 .   ? -46.157 -21.671 -58.541  1.00 39.31  ? 702  HOH D O   1 
HETATM 15858 O O   . HOH L 3 .   ? -22.610 3.892   -90.211  1.00 32.32  ? 703  HOH D O   1 
HETATM 15859 O O   . HOH L 3 .   ? -46.000 -20.582 -64.129  1.00 27.22  ? 704  HOH D O   1 
HETATM 15860 O O   . HOH L 3 .   ? -11.614 -15.094 -94.848  1.00 21.04  ? 705  HOH D O   1 
HETATM 15861 O O   . HOH L 3 .   ? -24.283 20.322  -64.425  1.00 26.76  ? 706  HOH D O   1 
HETATM 15862 O O   . HOH L 3 .   ? -21.552 -19.198 -31.943  1.00 47.89  ? 707  HOH D O   1 
HETATM 15863 O O   . HOH L 3 .   ? -10.880 -26.829 -78.596  1.00 22.80  ? 708  HOH D O   1 
HETATM 15864 O O   . HOH L 3 .   ? -38.152 -20.513 -74.151  1.00 40.80  ? 709  HOH D O   1 
HETATM 15865 O O   . HOH L 3 .   ? -25.633 -23.617 -54.532  1.00 51.89  ? 710  HOH D O   1 
HETATM 15866 O O   . HOH L 3 .   ? -5.010  -14.036 -93.722  1.00 51.59  ? 711  HOH D O   1 
HETATM 15867 O O   . HOH L 3 .   ? -11.282 -25.156 -67.876  1.00 53.97  ? 712  HOH D O   1 
HETATM 15868 O O   . HOH L 3 .   ? -24.383 3.502   -44.482  1.00 14.20  ? 713  HOH D O   1 
HETATM 15869 O O   . HOH L 3 .   ? -42.250 -2.287  -56.098  1.00 64.46  ? 714  HOH D O   1 
HETATM 15870 O O   . HOH L 3 .   ? -36.888 9.303   -70.756  1.00 41.68  ? 715  HOH D O   1 
HETATM 15871 O O   . HOH L 3 .   ? -33.874 7.258   -45.929  1.00 58.03  ? 716  HOH D O   1 
HETATM 15872 O O   . HOH L 3 .   ? -30.158 6.079   -64.228  1.00 28.96  ? 717  HOH D O   1 
HETATM 15873 O O   . HOH L 3 .   ? -15.432 -26.643 -82.312  1.00 32.49  ? 718  HOH D O   1 
HETATM 15874 O O   . HOH L 3 .   ? -7.188  -10.816 -94.108  1.00 36.51  ? 719  HOH D O   1 
HETATM 15875 O O   . HOH L 3 .   ? -20.820 -21.564 -60.586  1.00 34.93  ? 720  HOH D O   1 
HETATM 15876 O O   . HOH L 3 .   ? -46.894 -13.993 -65.503  1.00 63.35  ? 721  HOH D O   1 
HETATM 15877 O O   . HOH L 3 .   ? -10.766 -17.828 -91.118  1.00 59.71  ? 722  HOH D O   1 
HETATM 15878 O O   . HOH L 3 .   ? -30.140 10.704  -82.200  1.00 24.90  ? 723  HOH D O   1 
HETATM 15879 O O   . HOH L 3 .   ? -24.263 9.304   -85.696  1.00 33.35  ? 724  HOH D O   1 
HETATM 15880 O O   . HOH L 3 .   ? -19.815 -19.360 -73.358  1.00 23.15  ? 725  HOH D O   1 
HETATM 15881 O O   . HOH L 3 .   ? -10.302 17.422  -67.656  1.00 19.68  ? 726  HOH D O   1 
HETATM 15882 O O   . HOH L 3 .   ? -46.726 -6.329  -65.581  1.00 14.03  ? 727  HOH D O   1 
HETATM 15883 O O   . HOH L 3 .   ? -39.883 -24.765 -69.619  1.00 39.17  ? 728  HOH D O   1 
HETATM 15884 O O   . HOH L 3 .   ? -14.148 5.013   -91.096  1.00 17.66  ? 729  HOH D O   1 
HETATM 15885 O O   . HOH L 3 .   ? -16.905 0.449   -67.138  1.00 49.60  ? 730  HOH D O   1 
HETATM 15886 O O   . HOH L 3 .   ? -5.798  16.941  -75.251  1.00 15.01  ? 731  HOH D O   1 
HETATM 15887 O O   . HOH L 3 .   ? -24.743 -19.311 -68.855  1.00 47.52  ? 732  HOH D O   1 
HETATM 15888 O O   . HOH L 3 .   ? -20.747 -20.707 -80.618  1.00 15.44  ? 733  HOH D O   1 
HETATM 15889 O O   . HOH L 3 .   ? -33.076 12.152  -46.295  1.00 38.87  ? 734  HOH D O   1 
HETATM 15890 O O   . HOH L 3 .   ? -3.466  -0.303  -46.068  1.00 21.11  ? 735  HOH D O   1 
HETATM 15891 O O   . HOH L 3 .   ? -18.497 18.516  -48.051  1.00 30.03  ? 736  HOH D O   1 
HETATM 15892 O O   . HOH L 3 .   ? -37.109 -1.205  -79.120  1.00 46.53  ? 737  HOH D O   1 
HETATM 15893 O O   . HOH L 3 .   ? -13.870 -27.931 -89.321  1.00 37.31  ? 738  HOH D O   1 
HETATM 15894 O O   . HOH L 3 .   ? -24.505 -14.571 -87.942  1.00 27.76  ? 739  HOH D O   1 
HETATM 15895 O O   . HOH L 3 .   ? -17.506 -26.321 -63.928  1.00 27.81  ? 740  HOH D O   1 
HETATM 15896 O O   . HOH L 3 .   ? -22.319 -17.880 -90.553  1.00 49.94  ? 741  HOH D O   1 
HETATM 15897 O O   . HOH L 3 .   ? -23.246 21.999  -64.610  1.00 40.40  ? 742  HOH D O   1 
HETATM 15898 O O   . HOH L 3 .   ? -33.306 11.458  -66.315  1.00 44.11  ? 743  HOH D O   1 
HETATM 15899 O O   . HOH L 3 .   ? -14.407 15.147  -42.479  1.00 30.21  ? 744  HOH D O   1 
HETATM 15900 O O   . HOH L 3 .   ? -0.567  -8.731  -51.258  1.00 16.98  ? 745  HOH D O   1 
HETATM 15901 O O   . HOH L 3 .   ? -11.374 13.465  -29.285  1.00 25.51  ? 746  HOH D O   1 
HETATM 15902 O O   . HOH L 3 .   ? -18.579 23.871  -59.586  1.00 41.49  ? 747  HOH D O   1 
HETATM 15903 O O   . HOH L 3 .   ? -39.675 -16.764 -74.356  1.00 19.35  ? 748  HOH D O   1 
HETATM 15904 O O   . HOH L 3 .   ? -40.404 -10.192 -54.966  1.00 19.20  ? 749  HOH D O   1 
HETATM 15905 O O   . HOH L 3 .   ? -22.324 -2.693  -79.964  1.00 27.28  ? 750  HOH D O   1 
HETATM 15906 O O   . HOH L 3 .   ? -10.219 5.634   -35.729  1.00 24.04  ? 751  HOH D O   1 
HETATM 15907 O O   . HOH L 3 .   ? -38.814 1.559   -62.521  1.00 36.00  ? 752  HOH D O   1 
HETATM 15908 O O   . HOH L 3 .   ? -20.576 2.569   -38.077  1.00 32.28  ? 753  HOH D O   1 
HETATM 15909 O O   . HOH L 3 .   ? -17.691 19.244  -67.901  1.00 25.21  ? 754  HOH D O   1 
HETATM 15910 O O   . HOH L 3 .   ? -7.868  12.216  -69.952  1.00 25.54  ? 755  HOH D O   1 
HETATM 15911 O O   . HOH L 3 .   ? -7.991  12.016  -41.738  1.00 37.13  ? 756  HOH D O   1 
HETATM 15912 O O   . HOH L 3 .   ? -24.357 -0.049  -79.551  1.00 14.47  ? 757  HOH D O   1 
HETATM 15913 O O   . HOH L 3 .   ? -5.079  -2.975  -46.683  1.00 15.22  ? 758  HOH D O   1 
HETATM 15914 O O   . HOH L 3 .   ? -23.483 -16.735 -64.155  1.00 26.91  ? 759  HOH D O   1 
HETATM 15915 O O   . HOH L 3 .   ? -21.811 -2.388  -59.170  1.00 25.56  ? 760  HOH D O   1 
HETATM 15916 O O   . HOH L 3 .   ? -29.400 14.542  -66.873  1.00 25.46  ? 761  HOH D O   1 
HETATM 15917 O O   . HOH L 3 .   ? -45.043 -14.231 -64.571  1.00 32.25  ? 762  HOH D O   1 
HETATM 15918 O O   . HOH L 3 .   ? -44.828 -0.688  -67.043  1.00 14.04  ? 763  HOH D O   1 
HETATM 15919 O O   . HOH L 3 .   ? -40.790 -15.963 -53.716  1.00 39.40  ? 764  HOH D O   1 
HETATM 15920 O O   . HOH L 3 .   ? -50.705 -11.852 -58.718  1.00 26.27  ? 765  HOH D O   1 
HETATM 15921 O O   . HOH L 3 .   ? -15.476 -24.372 -95.497  1.00 41.67  ? 766  HOH D O   1 
HETATM 15922 O O   . HOH L 3 .   ? -21.866 -21.517 -88.398  1.00 34.18  ? 767  HOH D O   1 
HETATM 15923 O O   . HOH L 3 .   ? -9.729  15.456  -83.468  1.00 28.32  ? 768  HOH D O   1 
HETATM 15924 O O   . HOH L 3 .   ? -9.878  14.040  -69.644  1.00 46.06  ? 769  HOH D O   1 
HETATM 15925 O O   . HOH L 3 .   ? -21.570 -26.841 -69.400  1.00 56.26  ? 770  HOH D O   1 
HETATM 15926 O O   . HOH L 3 .   ? -24.052 -3.002  -46.385  1.00 6.38   ? 771  HOH D O   1 
HETATM 15927 O O   . HOH L 3 .   ? -31.491 9.899   -56.134  1.00 30.07  ? 772  HOH D O   1 
HETATM 15928 O O   . HOH L 3 .   ? -32.715 -3.512  -51.754  1.00 34.74  ? 773  HOH D O   1 
HETATM 15929 O O   . HOH L 3 .   ? -4.646  9.863   -85.146  1.00 24.25  ? 774  HOH D O   1 
HETATM 15930 O O   . HOH L 3 .   ? -33.539 -16.202 -79.333  1.00 47.94  ? 775  HOH D O   1 
HETATM 15931 O O   . HOH L 3 .   ? -37.405 4.278   -62.283  1.00 20.56  ? 776  HOH D O   1 
HETATM 15932 O O   . HOH L 3 .   ? -2.614  21.522  -60.135  1.00 30.50  ? 777  HOH D O   1 
HETATM 15933 O O   . HOH L 3 .   ? -25.108 7.980   -35.342  1.00 25.16  ? 778  HOH D O   1 
HETATM 15934 O O   . HOH L 3 .   ? -24.009 0.556   -58.861  1.00 11.15  ? 779  HOH D O   1 
HETATM 15935 O O   . HOH L 3 .   ? -24.454 -8.970  -73.210  1.00 26.66  ? 780  HOH D O   1 
HETATM 15936 O O   . HOH L 3 .   ? -46.123 -8.281  -59.189  1.00 44.32  ? 781  HOH D O   1 
HETATM 15937 O O   . HOH L 3 .   ? -11.352 15.266  -85.185  1.00 27.33  ? 782  HOH D O   1 
HETATM 15938 O O   . HOH L 3 .   ? -25.280 18.209  -36.410  1.00 48.77  ? 783  HOH D O   1 
HETATM 15939 O O   . HOH L 3 .   ? 0.387   -2.362  -51.173  1.00 22.22  ? 784  HOH D O   1 
HETATM 15940 O O   . HOH L 3 .   ? -31.026 16.550  -81.678  1.00 38.08  ? 785  HOH D O   1 
HETATM 15941 O O   . HOH L 3 .   ? -9.958  15.434  -35.768  1.00 39.42  ? 786  HOH D O   1 
HETATM 15942 O O   . HOH L 3 .   ? -27.488 17.471  -53.310  1.00 28.52  ? 787  HOH D O   1 
HETATM 15943 O O   . HOH L 3 .   ? -8.686  -12.978 -41.972  1.00 30.60  ? 788  HOH D O   1 
HETATM 15944 O O   . HOH L 3 .   ? -4.777  15.893  -78.695  1.00 39.23  ? 789  HOH D O   1 
HETATM 15945 O O   . HOH L 3 .   ? -35.428 12.236  -73.165  1.00 39.40  ? 790  HOH D O   1 
HETATM 15946 O O   . HOH L 3 .   ? -33.640 -27.756 -60.543  1.00 46.29  ? 791  HOH D O   1 
HETATM 15947 O O   . HOH L 3 .   ? -12.713 23.796  -47.504  1.00 47.55  ? 792  HOH D O   1 
HETATM 15948 O O   . HOH L 3 .   ? -2.240  -9.987  -48.586  1.00 21.24  ? 793  HOH D O   1 
HETATM 15949 O O   . HOH L 3 .   ? -5.786  7.399   -46.388  1.00 24.62  ? 794  HOH D O   1 
HETATM 15950 O O   . HOH L 3 .   ? -18.784 -22.632 -97.443  1.00 50.55  ? 795  HOH D O   1 
HETATM 15951 O O   . HOH L 3 .   ? -9.284  24.126  -55.035  1.00 52.53  ? 796  HOH D O   1 
HETATM 15952 O O   . HOH L 3 .   ? -16.056 18.355  -39.712  1.00 35.50  ? 797  HOH D O   1 
HETATM 15953 O O   . HOH L 3 .   ? -20.632 -0.716  -89.399  1.00 24.64  ? 798  HOH D O   1 
HETATM 15954 O O   . HOH L 3 .   ? -25.355 0.428   -76.164  1.00 28.49  ? 799  HOH D O   1 
HETATM 15955 O O   . HOH L 3 .   ? -30.912 -13.013 -86.307  1.00 46.53  ? 800  HOH D O   1 
HETATM 15956 O O   . HOH L 3 .   ? 1.405   9.537   -71.948  1.00 37.50  ? 801  HOH D O   1 
HETATM 15957 O O   . HOH L 3 .   ? -16.228 -8.108  -91.073  1.00 22.56  ? 802  HOH D O   1 
HETATM 15958 O O   . HOH L 3 .   ? -6.720  12.876  -48.499  1.00 16.35  ? 803  HOH D O   1 
HETATM 15959 O O   . HOH L 3 .   ? -24.693 -7.264  -51.086  1.00 33.23  ? 804  HOH D O   1 
HETATM 15960 O O   . HOH L 3 .   ? -23.052 2.347   -60.395  1.00 23.46  ? 805  HOH D O   1 
HETATM 15961 O O   . HOH L 3 .   ? -48.540 -8.595  -60.182  1.00 32.73  ? 806  HOH D O   1 
HETATM 15962 O O   . HOH L 3 .   ? -42.859 -11.032 -55.417  1.00 32.97  ? 807  HOH D O   1 
HETATM 15963 O O   . HOH L 3 .   ? -4.650  24.438  -58.736  1.00 24.32  ? 808  HOH D O   1 
HETATM 15964 O O   . HOH L 3 .   ? -38.089 8.406   -59.268  1.00 45.70  ? 809  HOH D O   1 
HETATM 15965 O O   . HOH L 3 .   ? -13.189 -1.602  -68.267  1.00 11.41  ? 810  HOH D O   1 
HETATM 15966 O O   . HOH L 3 .   ? -1.074  17.403  -50.654  1.00 63.59  ? 811  HOH D O   1 
HETATM 15967 O O   . HOH L 3 .   ? -12.829 19.341  -45.722  1.00 36.20  ? 812  HOH D O   1 
HETATM 15968 O O   . HOH L 3 .   ? -11.666 8.034   -73.091  1.00 14.97  ? 813  HOH D O   1 
HETATM 15969 O O   . HOH L 3 .   ? -5.043  6.124   -48.889  1.00 28.32  ? 814  HOH D O   1 
HETATM 15970 O O   . HOH L 3 .   ? -4.205  7.494   -65.552  1.00 27.90  ? 815  HOH D O   1 
HETATM 15971 O O   . HOH L 3 .   ? -36.629 -25.884 -54.941  1.00 45.84  ? 816  HOH D O   1 
HETATM 15972 O O   . HOH L 3 .   ? -22.263 -3.564  -55.607  1.00 20.10  ? 817  HOH D O   1 
HETATM 15973 O O   . HOH L 3 .   ? -23.380 -16.766 -86.729  1.00 28.02  ? 818  HOH D O   1 
HETATM 15974 O O   . HOH L 3 .   ? -3.689  21.822  -56.398  1.00 32.22  ? 819  HOH D O   1 
HETATM 15975 O O   . HOH L 3 .   ? -20.177 8.284   -32.598  1.00 28.29  ? 820  HOH D O   1 
HETATM 15976 O O   . HOH L 3 .   ? -28.458 -16.915 -69.805  1.00 15.16  ? 821  HOH D O   1 
HETATM 15977 O O   . HOH L 3 .   ? -11.257 5.442   -74.379  1.00 23.97  ? 822  HOH D O   1 
HETATM 15978 O O   . HOH L 3 .   ? -33.744 -6.408  -80.879  1.00 24.12  ? 823  HOH D O   1 
HETATM 15979 O O   . HOH L 3 .   ? -24.639 3.560   -88.685  1.00 13.66  ? 824  HOH D O   1 
HETATM 15980 O O   . HOH L 3 .   ? -42.320 4.770   -68.479  1.00 48.30  ? 825  HOH D O   1 
HETATM 15981 O O   . HOH L 3 .   ? -38.489 8.504   -66.236  1.00 55.87  ? 826  HOH D O   1 
HETATM 15982 O O   . HOH L 3 .   ? -21.690 1.386   -52.431  1.00 11.32  ? 827  HOH D O   1 
HETATM 15983 O O   . HOH L 3 .   ? -25.957 -20.602 -51.826  1.00 34.42  ? 828  HOH D O   1 
HETATM 15984 O O   . HOH L 3 .   ? -19.571 2.318   -51.096  1.00 3.93   ? 829  HOH D O   1 
HETATM 15985 O O   . HOH L 3 .   ? -19.659 1.884   -74.167  1.00 11.71  ? 830  HOH D O   1 
HETATM 15986 O O   . HOH L 3 .   ? -12.488 -3.004  -62.733  1.00 23.12  ? 831  HOH D O   1 
HETATM 15987 O O   . HOH L 3 .   ? -36.741 -19.723 -76.340  1.00 36.95  ? 832  HOH D O   1 
HETATM 15988 O O   . HOH L 3 .   ? -24.909 -17.107 -67.664  1.00 25.59  ? 833  HOH D O   1 
HETATM 15989 O O   . HOH L 3 .   ? -10.887 13.841  -78.451  1.00 18.32  ? 834  HOH D O   1 
HETATM 15990 O O   . HOH L 3 .   ? -31.872 6.483   -51.275  1.00 38.27  ? 835  HOH D O   1 
HETATM 15991 O O   . HOH L 3 .   ? -16.932 -16.526 -95.926  1.00 37.79  ? 836  HOH D O   1 
HETATM 15992 O O   . HOH L 3 .   ? -25.062 2.641   -73.806  1.00 24.97  ? 837  HOH D O   1 
HETATM 15993 O O   . HOH L 3 .   ? -23.561 3.015   -67.331  1.00 7.92   ? 838  HOH D O   1 
HETATM 15994 O O   . HOH L 3 .   ? -28.095 -4.102  -84.136  1.00 13.45  ? 839  HOH D O   1 
HETATM 15995 O O   . HOH L 3 .   ? -17.183 -28.182 -75.752  1.00 34.71  ? 840  HOH D O   1 
HETATM 15996 O O   . HOH L 3 .   ? -22.044 5.499   -66.335  1.00 12.13  ? 841  HOH D O   1 
HETATM 15997 O O   . HOH L 3 .   ? -10.721 -21.151 -87.759  1.00 39.39  ? 842  HOH D O   1 
HETATM 15998 O O   . HOH L 3 .   ? 1.766   19.283  -59.161  1.00 60.71  ? 843  HOH D O   1 
HETATM 15999 O O   . HOH L 3 .   ? -26.525 20.697  -46.392  1.00 29.54  ? 844  HOH D O   1 
HETATM 16000 O O   . HOH L 3 .   ? -26.816 16.493  -41.320  1.00 32.76  ? 845  HOH D O   1 
HETATM 16001 O O   . HOH L 3 .   ? -20.761 -14.686 -62.760  1.00 28.68  ? 846  HOH D O   1 
HETATM 16002 O O   . HOH L 3 .   ? -17.638 20.777  -54.107  1.00 22.74  ? 847  HOH D O   1 
HETATM 16003 O O   . HOH L 3 .   ? -14.368 4.135   -38.888  1.00 49.90  ? 848  HOH D O   1 
HETATM 16004 O O   . HOH L 3 .   ? -24.546 -4.847  -49.376  1.00 22.69  ? 849  HOH D O   1 
HETATM 16005 O O   . HOH L 3 .   ? -12.622 -14.181 -48.644  1.00 47.40  ? 850  HOH D O   1 
HETATM 16006 O O   . HOH L 3 .   ? -22.061 -5.551  -79.385  1.00 18.76  ? 851  HOH D O   1 
HETATM 16007 O O   . HOH L 3 .   ? -45.573 -7.218  -54.157  1.00 36.31  ? 852  HOH D O   1 
HETATM 16008 O O   . HOH L 3 .   ? -5.469  11.938  -73.068  1.00 34.95  ? 853  HOH D O   1 
HETATM 16009 O O   . HOH L 3 .   ? 2.533   23.862  -63.811  1.00 49.65  ? 854  HOH D O   1 
HETATM 16010 O O   . HOH L 3 .   ? -17.950 -0.407  -39.601  1.00 32.98  ? 855  HOH D O   1 
HETATM 16011 O O   . HOH L 3 .   ? -9.575  -0.854  -46.173  1.00 35.70  ? 856  HOH D O   1 
HETATM 16012 O O   . HOH L 3 .   ? -8.120  7.626   -64.226  1.00 29.83  ? 857  HOH D O   1 
HETATM 16013 O O   . HOH L 3 .   ? -40.664 -26.827 -67.638  1.00 51.43  ? 858  HOH D O   1 
HETATM 16014 O O   . HOH L 3 .   ? -16.724 -11.263 -83.409  1.00 17.04  ? 859  HOH D O   1 
HETATM 16015 O O   . HOH L 3 .   ? -32.113 -25.659 -58.886  1.00 47.04  ? 860  HOH D O   1 
HETATM 16016 O O   . HOH L 3 .   ? -42.662 -5.219  -79.299  1.00 14.39  ? 861  HOH D O   1 
HETATM 16017 O O   . HOH L 3 .   ? -11.513 15.198  -80.443  1.00 23.50  ? 862  HOH D O   1 
HETATM 16018 O O   . HOH L 3 .   ? -26.392 -2.832  -44.930  1.00 52.86  ? 863  HOH D O   1 
HETATM 16019 O O   . HOH L 3 .   ? -42.706 -3.558  -60.859  1.00 43.65  ? 864  HOH D O   1 
HETATM 16020 O O   . HOH L 3 .   ? -5.799  11.871  -39.973  1.00 11.24  ? 865  HOH D O   1 
HETATM 16021 O O   . HOH L 3 .   ? -5.203  -10.918 -46.685  1.00 59.81  ? 866  HOH D O   1 
HETATM 16022 O O   . HOH L 3 .   ? -41.922 -2.143  -78.026  1.00 22.94  ? 867  HOH D O   1 
HETATM 16023 O O   . HOH L 3 .   ? -4.072  17.105  -63.779  1.00 50.17  ? 868  HOH D O   1 
HETATM 16024 O O   . HOH L 3 .   ? -37.476 -3.153  -62.339  1.00 22.47  ? 869  HOH D O   1 
HETATM 16025 O O   . HOH L 3 .   ? -16.892 28.852  -60.551  1.00 42.82  ? 870  HOH D O   1 
HETATM 16026 O O   . HOH L 3 .   ? -14.484 12.669  -39.859  1.00 25.90  ? 871  HOH D O   1 
HETATM 16027 O O   . HOH L 3 .   ? -14.473 20.365  -41.600  1.00 36.04  ? 872  HOH D O   1 
HETATM 16028 O O   . HOH L 3 .   ? -12.374 -18.436 -32.588  1.00 52.21  ? 873  HOH D O   1 
HETATM 16029 O O   . HOH L 3 .   ? -27.719 -1.321  -41.986  1.00 37.51  ? 874  HOH D O   1 
HETATM 16030 O O   . HOH L 3 .   ? -29.503 14.830  -59.131  1.00 40.48  ? 875  HOH D O   1 
HETATM 16031 O O   . HOH L 3 .   ? -17.635 24.540  -57.224  1.00 32.03  ? 876  HOH D O   1 
HETATM 16032 O O   . HOH L 3 .   ? -34.221 15.888  -59.407  1.00 41.16  ? 877  HOH D O   1 
HETATM 16033 O O   . HOH L 3 .   ? -31.698 15.825  -51.994  1.00 32.36  ? 878  HOH D O   1 
HETATM 16034 O O   . HOH L 3 .   ? -27.998 13.880  -42.622  1.00 26.28  ? 879  HOH D O   1 
HETATM 16035 O O   . HOH L 3 .   ? -20.490 6.629   -90.937  1.00 30.26  ? 880  HOH D O   1 
HETATM 16036 O O   . HOH L 3 .   ? -2.482  -17.737 -91.563  1.00 30.99  ? 881  HOH D O   1 
HETATM 16037 O O   . HOH L 3 .   ? -40.516 -8.980  -51.839  1.00 38.48  ? 882  HOH D O   1 
HETATM 16038 O O   . HOH L 3 .   ? -12.470 -12.533 -44.736  1.00 30.58  ? 883  HOH D O   1 
HETATM 16039 O O   . HOH L 3 .   ? -38.695 -17.775 -51.000  1.00 25.37  ? 884  HOH D O   1 
HETATM 16040 O O   . HOH L 3 .   ? -30.015 3.889   -39.761  1.00 17.67  ? 885  HOH D O   1 
HETATM 16041 O O   . HOH L 3 .   ? -7.820  0.627   -45.154  1.00 20.86  ? 886  HOH D O   1 
HETATM 16042 O O   . HOH L 3 .   ? -32.488 3.115   -80.900  1.00 35.65  ? 887  HOH D O   1 
HETATM 16043 O O   . HOH L 3 .   ? -46.934 -12.519 -72.491  1.00 29.82  ? 888  HOH D O   1 
HETATM 16044 O O   . HOH L 3 .   ? -25.948 1.327   -67.083  1.00 16.93  ? 889  HOH D O   1 
HETATM 16045 O O   . HOH L 3 .   ? -38.157 -0.696  -61.290  1.00 33.79  ? 890  HOH D O   1 
HETATM 16046 O O   . HOH L 3 .   ? -14.109 16.391  -85.106  1.00 33.64  ? 891  HOH D O   1 
HETATM 16047 O O   . HOH L 3 .   ? -45.033 -13.194 -70.800  1.00 28.90  ? 892  HOH D O   1 
HETATM 16048 O O   . HOH L 3 .   ? -10.633 8.796   -94.537  1.00 24.43  ? 893  HOH D O   1 
HETATM 16049 O O   . HOH L 3 .   ? -7.923  -14.085 -66.827  1.00 41.36  ? 894  HOH D O   1 
HETATM 16050 O O   . HOH L 3 .   ? 5.611   20.795  -76.587  1.00 59.69  ? 895  HOH D O   1 
HETATM 16051 O O   . HOH L 3 .   ? -22.236 10.750  -86.843  1.00 48.17  ? 896  HOH D O   1 
HETATM 16052 O O   . HOH L 3 .   ? -35.313 -16.797 -77.358  1.00 43.82  ? 897  HOH D O   1 
HETATM 16053 O O   . HOH L 3 .   ? -22.891 21.770  -50.182  1.00 30.54  ? 898  HOH D O   1 
HETATM 16054 O O   . HOH L 3 .   ? -5.912  10.162  -48.208  1.00 34.36  ? 899  HOH D O   1 
HETATM 16055 O O   . HOH L 3 .   ? -14.368 -4.742  -63.066  1.00 28.35  ? 900  HOH D O   1 
HETATM 16056 O O   . HOH L 3 .   ? -39.340 -7.922  -80.889  1.00 14.84  ? 901  HOH D O   1 
HETATM 16057 O O   . HOH L 3 .   ? -30.659 5.168   -43.436  1.00 12.16  ? 902  HOH D O   1 
HETATM 16058 O O   . HOH L 3 .   ? -26.954 0.702   -36.929  1.00 23.45  ? 903  HOH D O   1 
HETATM 16059 O O   . HOH L 3 .   ? -11.349 -14.872 -45.340  1.00 69.45  ? 904  HOH D O   1 
HETATM 16060 O O   . HOH L 3 .   ? -33.958 -10.298 -83.831  1.00 36.28  ? 905  HOH D O   1 
HETATM 16061 O O   . HOH L 3 .   ? -27.690 -17.339 -35.407  1.00 38.21  ? 906  HOH D O   1 
HETATM 16062 O O   . HOH L 3 .   ? -37.782 11.063  -59.063  1.00 63.37  ? 907  HOH D O   1 
HETATM 16063 O O   . HOH L 3 .   ? -8.570  17.391  -40.183  1.00 34.64  ? 908  HOH D O   1 
HETATM 16064 O O   . HOH L 3 .   ? -30.716 4.581   -82.810  1.00 21.33  ? 909  HOH D O   1 
HETATM 16065 O O   . HOH L 3 .   ? -26.471 19.403  -43.657  1.00 37.12  ? 910  HOH D O   1 
HETATM 16066 O O   . HOH L 3 .   ? -10.248 25.601  -52.896  1.00 40.97  ? 911  HOH D O   1 
HETATM 16067 O O   . HOH L 3 .   ? -12.388 5.112   -36.515  1.00 13.02  ? 912  HOH D O   1 
HETATM 16068 O O   . HOH L 3 .   ? -29.850 -25.415 -76.162  1.00 65.62  ? 913  HOH D O   1 
HETATM 16069 O O   . HOH L 3 .   ? -48.149 -9.977  -62.411  1.00 22.52  ? 914  HOH D O   1 
HETATM 16070 O O   . HOH L 3 .   ? -23.083 -24.962 -88.382  1.00 22.51  ? 915  HOH D O   1 
HETATM 16071 O O   . HOH L 3 .   ? -22.310 9.154   -91.607  1.00 26.38  ? 916  HOH D O   1 
HETATM 16072 O O   . HOH L 3 .   ? -35.910 14.702  -52.866  1.00 37.56  ? 917  HOH D O   1 
HETATM 16073 O O   . HOH L 3 .   ? -16.216 -11.969 -49.784  1.00 38.25  ? 918  HOH D O   1 
HETATM 16074 O O   . HOH L 3 .   ? -44.133 -19.235 -70.236  1.00 28.80  ? 919  HOH D O   1 
HETATM 16075 O O   . HOH L 3 .   ? -26.422 -23.189 -80.179  1.00 41.66  ? 920  HOH D O   1 
HETATM 16076 O O   . HOH L 3 .   ? -31.319 4.987   -54.742  1.00 56.30  ? 921  HOH D O   1 
HETATM 16077 O O   . HOH L 3 .   ? -40.075 -0.303  -77.332  1.00 25.97  ? 922  HOH D O   1 
HETATM 16078 O O   . HOH L 3 .   ? -24.244 -6.844  -87.062  1.00 24.37  ? 923  HOH D O   1 
HETATM 16079 O O   . HOH L 3 .   ? 6.494   -16.671 -83.831  1.00 47.10  ? 924  HOH D O   1 
HETATM 16080 O O   . HOH L 3 .   ? -18.959 20.294  -46.679  1.00 48.86  ? 925  HOH D O   1 
HETATM 16081 O O   . HOH L 3 .   ? -28.924 17.231  -48.600  1.00 41.01  ? 926  HOH D O   1 
HETATM 16082 O O   . HOH L 3 .   ? -0.062  -24.401 -75.693  1.00 39.92  ? 927  HOH D O   1 
HETATM 16083 O O   . HOH L 3 .   ? -18.940 -7.138  -48.838  1.00 32.68  ? 928  HOH D O   1 
HETATM 16084 O O   . HOH L 3 .   ? -23.639 -22.382 -91.971  1.00 53.22  ? 929  HOH D O   1 
HETATM 16085 O O   . HOH L 3 .   ? -4.857  8.651   -77.441  1.00 44.80  ? 930  HOH D O   1 
HETATM 16086 O O   . HOH L 3 .   ? -23.964 -24.063 -56.942  1.00 53.40  ? 931  HOH D O   1 
HETATM 16087 O O   . HOH L 3 .   ? -35.859 2.614   -78.217  1.00 26.79  ? 932  HOH D O   1 
HETATM 16088 O O   . HOH L 3 .   ? -30.394 1.741   -41.622  1.00 46.65  ? 933  HOH D O   1 
HETATM 16089 O O   . HOH L 3 .   ? -23.447 -15.708 -90.727  1.00 28.69  ? 934  HOH D O   1 
HETATM 16090 O O   . HOH L 3 .   ? -38.450 6.622   -62.972  1.00 31.17  ? 935  HOH D O   1 
HETATM 16091 O O   . HOH L 3 .   ? -6.189  0.719   -43.097  1.00 25.43  ? 936  HOH D O   1 
HETATM 16092 O O   . HOH L 3 .   ? -20.009 -8.684  -50.991  1.00 32.76  ? 937  HOH D O   1 
HETATM 16093 O O   . HOH L 3 .   ? -24.739 -22.520 -78.038  1.00 43.23  ? 938  HOH D O   1 
HETATM 16094 O O   . HOH L 3 .   ? -25.841 -3.560  -48.601  1.00 35.77  ? 939  HOH D O   1 
HETATM 16095 O O   . HOH L 3 .   ? -9.205  -27.263 -75.851  1.00 40.34  ? 940  HOH D O   1 
HETATM 16096 O O   . HOH L 3 .   ? -18.070 -15.278 -36.905  1.00 28.11  ? 941  HOH D O   1 
HETATM 16097 O O   . HOH L 3 .   ? -19.039 19.446  -50.079  1.00 31.70  ? 942  HOH D O   1 
HETATM 16098 O O   . HOH L 3 .   ? -31.910 7.509   -37.933  1.00 31.95  ? 943  HOH D O   1 
HETATM 16099 O O   . HOH L 3 .   ? -50.284 -18.430 -62.327  1.00 25.60  ? 944  HOH D O   1 
HETATM 16100 O O   . HOH L 3 .   ? -26.252 -5.814  -85.873  1.00 30.23  ? 945  HOH D O   1 
HETATM 16101 O O   . HOH L 3 .   ? -15.997 -29.202 -83.083  1.00 38.12  ? 946  HOH D O   1 
HETATM 16102 O O   . HOH L 3 .   ? -43.109 -25.948 -62.722  1.00 54.71  ? 947  HOH D O   1 
HETATM 16103 O O   . HOH L 3 .   ? -14.702 15.427  -39.736  1.00 21.12  ? 948  HOH D O   1 
HETATM 16104 O O   . HOH L 3 .   ? -38.188 0.784   -78.344  1.00 29.13  ? 949  HOH D O   1 
HETATM 16105 O O   . HOH L 3 .   ? -37.578 -3.747  -55.665  1.00 20.67  ? 950  HOH D O   1 
HETATM 16106 O O   . HOH L 3 .   ? -46.310 0.651   -74.095  1.00 28.83  ? 951  HOH D O   1 
HETATM 16107 O O   . HOH L 3 .   ? -41.879 3.524   -72.929  1.00 31.49  ? 952  HOH D O   1 
HETATM 16108 O O   . HOH L 3 .   ? -31.321 -18.803 -83.889  1.00 34.81  ? 953  HOH D O   1 
HETATM 16109 O O   . HOH L 3 .   ? -32.551 -3.724  -84.898  1.00 21.94  ? 954  HOH D O   1 
HETATM 16110 O O   . HOH L 3 .   ? -23.498 -19.426 -88.510  1.00 25.22  ? 955  HOH D O   1 
HETATM 16111 O O   . HOH L 3 .   ? -6.292  6.854   -65.298  1.00 30.81  ? 956  HOH D O   1 
HETATM 16112 O O   . HOH L 3 .   ? -4.055  -19.515 -85.501  1.00 42.56  ? 957  HOH D O   1 
HETATM 16113 O O   . HOH L 3 .   ? -22.456 -28.867 -77.744  1.00 48.27  ? 958  HOH D O   1 
HETATM 16114 O O   . HOH L 3 .   ? -12.631 -20.493 -89.365  1.00 23.13  ? 959  HOH D O   1 
HETATM 16115 O O   . HOH L 3 .   ? -37.868 7.747   -56.547  1.00 36.44  ? 960  HOH D O   1 
HETATM 16116 O O   . HOH L 3 .   ? -24.337 19.741  -51.833  1.00 59.02  ? 961  HOH D O   1 
HETATM 16117 O O   . HOH L 3 .   ? -22.193 -2.814  -91.300  1.00 30.56  ? 962  HOH D O   1 
HETATM 16118 O O   . HOH L 3 .   ? -27.104 7.218   -87.459  1.00 51.71  ? 963  HOH D O   1 
HETATM 16119 O O   . HOH L 3 .   ? -23.909 -25.753 -85.818  1.00 39.47  ? 964  HOH D O   1 
HETATM 16120 O O   . HOH L 3 .   ? -23.791 2.689   -34.856  1.00 38.92  ? 965  HOH D O   1 
HETATM 16121 O O   . HOH L 3 .   ? -22.583 12.324  -34.878  1.00 33.30  ? 966  HOH D O   1 
HETATM 16122 O O   . HOH L 3 .   ? -21.604 15.776  -35.220  1.00 46.55  ? 967  HOH D O   1 
HETATM 16123 O O   . HOH L 3 .   ? -13.629 -16.240 -95.973  1.00 43.58  ? 968  HOH D O   1 
HETATM 16124 O O   . HOH L 3 .   ? -22.596 8.559   -33.283  1.00 28.86  ? 969  HOH D O   1 
HETATM 16125 O O   . HOH L 3 .   ? -36.575 10.321  -67.477  1.00 43.91  ? 970  HOH D O   1 
HETATM 16126 O O   . HOH L 3 .   ? -11.690 28.892  -64.617  1.00 35.66  ? 971  HOH D O   1 
HETATM 16127 O O   . HOH L 3 .   ? -35.896 16.772  -79.688  1.00 35.48  ? 972  HOH D O   1 
HETATM 16128 O O   . HOH L 3 .   ? -32.156 -16.527 -50.281  1.00 33.27  ? 973  HOH D O   1 
HETATM 16129 O O   . HOH L 3 .   ? -15.890 -13.901 -37.537  1.00 51.24  ? 974  HOH D O   1 
HETATM 16130 O O   . HOH L 3 .   ? -26.146 -17.522 -59.248  1.00 29.95  ? 975  HOH D O   1 
HETATM 16131 O O   . HOH L 3 .   ? -34.574 -13.861 -81.002  1.00 26.38  ? 976  HOH D O   1 
HETATM 16132 O O   . HOH L 3 .   ? -26.751 -10.696 -87.632  1.00 29.41  ? 977  HOH D O   1 
HETATM 16133 O O   . HOH L 3 .   ? -31.266 7.243   -53.933  1.00 50.39  ? 978  HOH D O   1 
HETATM 16134 O O   . HOH L 3 .   ? -9.170  -26.313 -85.796  1.00 37.72  ? 979  HOH D O   1 
HETATM 16135 O O   . HOH L 3 .   ? -28.656 11.396  -35.299  1.00 29.70  ? 980  HOH D O   1 
HETATM 16136 O O   . HOH L 3 .   ? -23.383 -22.231 -29.483  1.00 36.49  ? 981  HOH D O   1 
HETATM 16137 O O   . HOH L 3 .   ? -29.046 -15.556 -87.079  1.00 25.42  ? 982  HOH D O   1 
HETATM 16138 O O   . HOH L 3 .   ? -31.810 9.071   -81.811  1.00 29.89  ? 983  HOH D O   1 
HETATM 16139 O O   . HOH L 3 .   ? -12.255 -25.678 -91.458  1.00 43.50  ? 984  HOH D O   1 
HETATM 16140 O O   . HOH L 3 .   ? -24.574 20.716  -42.910  1.00 52.02  ? 985  HOH D O   1 
HETATM 16141 O O   . HOH L 3 .   ? -26.429 -22.112 -89.127  1.00 39.39  ? 986  HOH D O   1 
HETATM 16142 O O   . HOH L 3 .   ? -22.991 0.763   -90.385  1.00 37.26  ? 987  HOH D O   1 
HETATM 16143 O O   . HOH L 3 .   ? -36.296 -11.609 -80.428  1.00 28.41  ? 988  HOH D O   1 
HETATM 16144 O O   . HOH L 3 .   ? -45.885 -2.258  -65.344  1.00 25.19  ? 989  HOH D O   1 
HETATM 16145 O O   . HOH L 3 .   ? -9.293  22.477  -42.854  1.00 37.57  ? 990  HOH D O   1 
HETATM 16146 O O   . HOH L 3 .   ? 6.496   -14.340 -86.821  1.00 12.79  ? 991  HOH D O   1 
HETATM 16147 O O   . HOH L 3 .   ? -8.979  16.243  -69.645  1.00 33.56  ? 992  HOH D O   1 
HETATM 16148 O O   . HOH L 3 .   ? -19.362 7.997   -26.762  1.00 21.58  ? 993  HOH D O   1 
HETATM 16149 O O   . HOH L 3 .   ? -2.332  -21.096 -85.469  1.00 30.41  ? 994  HOH D O   1 
HETATM 16150 O O   . HOH L 3 .   ? -44.712 3.123   -65.943  1.00 46.51  ? 995  HOH D O   1 
HETATM 16151 O O   . HOH L 3 .   ? -21.636 24.502  -62.632  1.00 46.27  ? 996  HOH D O   1 
HETATM 16152 O O   . HOH L 3 .   ? -23.886 -19.316 -92.638  1.00 19.89  ? 997  HOH D O   1 
HETATM 16153 O O   . HOH L 3 .   ? -30.190 -8.490  -50.721  1.00 42.84  ? 998  HOH D O   1 
HETATM 16154 O O   . HOH L 3 .   ? -32.102 -27.023 -63.106  1.00 59.22  ? 999  HOH D O   1 
HETATM 16155 O O   . HOH L 3 .   ? -42.863 -13.705 -53.424  1.00 41.00  ? 1000 HOH D O   1 
HETATM 16156 O O   . HOH L 3 .   ? -36.420 14.856  -77.620  1.00 31.31  ? 1001 HOH D O   1 
HETATM 16157 O O   . HOH L 3 .   ? -14.744 21.164  -47.035  1.00 53.07  ? 1002 HOH D O   1 
HETATM 16158 O O   . HOH L 3 .   ? -43.998 -22.085 -68.196  1.00 39.85  ? 1003 HOH D O   1 
HETATM 16159 O O   . HOH L 3 .   ? -33.951 9.854   -44.835  1.00 26.93  ? 1004 HOH D O   1 
HETATM 16160 O O   . HOH L 3 .   ? -47.004 -13.383 -52.423  1.00 34.31  ? 1005 HOH D O   1 
HETATM 16161 O O   . HOH L 3 .   ? -16.348 2.104   -39.898  1.00 67.58  ? 1006 HOH D O   1 
HETATM 16162 O O   . HOH L 3 .   ? -46.011 -21.581 -54.253  1.00 48.60  ? 1007 HOH D O   1 
HETATM 16163 O O   . HOH L 3 .   ? -44.963 -2.232  -61.227  1.00 50.88  ? 1008 HOH D O   1 
HETATM 16164 O O   . HOH L 3 .   ? -23.811 -16.456 -59.162  1.00 23.38  ? 1009 HOH D O   1 
HETATM 16165 O O   . HOH L 3 .   ? -2.454  -19.674 -87.723  1.00 29.60  ? 1010 HOH D O   1 
HETATM 16166 O O   . HOH L 3 .   ? -21.318 22.263  -54.511  1.00 34.87  ? 1011 HOH D O   1 
HETATM 16167 O O   . HOH L 3 .   ? -19.353 -27.873 -94.034  1.00 40.20  ? 1012 HOH D O   1 
HETATM 16168 O O   . HOH L 3 .   ? -19.702 -13.997 -60.930  1.00 43.51  ? 1013 HOH D O   1 
HETATM 16169 O O   . HOH L 3 .   ? -26.916 -3.046  -40.574  1.00 26.54  ? 1014 HOH D O   1 
HETATM 16170 O O   . HOH L 3 .   ? -35.781 0.590   -79.910  1.00 33.38  ? 1015 HOH D O   1 
HETATM 16171 O O   . HOH L 3 .   ? -21.512 -15.838 -58.552  1.00 22.92  ? 1016 HOH D O   1 
HETATM 16172 O O   . HOH L 3 .   ? -28.445 -2.950  -85.861  1.00 33.38  ? 1017 HOH D O   1 
HETATM 16173 O O   . HOH L 3 .   ? -6.681  5.598   -62.967  1.00 57.21  ? 1018 HOH D O   1 
HETATM 16174 O O   . HOH L 3 .   ? -41.403 -5.860  -81.626  1.00 33.98  ? 1019 HOH D O   1 
HETATM 16175 O O   . HOH L 3 .   ? -14.594 15.206  -31.584  1.00 38.82  ? 1020 HOH D O   1 
HETATM 16176 O O   . HOH L 3 .   ? -2.313  -9.324  -46.066  1.00 36.11  ? 1021 HOH D O   1 
HETATM 16177 O O   . HOH L 3 .   ? -41.562 0.966   -75.470  1.00 57.52  ? 1022 HOH D O   1 
HETATM 16178 O O   . HOH L 3 .   ? -46.524 -2.901  -63.149  1.00 40.05  ? 1023 HOH D O   1 
HETATM 16179 O O   . HOH L 3 .   ? -17.098 16.413  -32.339  1.00 29.47  ? 1024 HOH D O   1 
HETATM 16180 O O   . HOH L 3 .   ? -4.625  8.194   -44.273  1.00 27.39  ? 1025 HOH D O   1 
HETATM 16181 O O   . HOH L 3 .   ? -3.866  13.832  -40.349  1.00 27.20  ? 1026 HOH D O   1 
HETATM 16182 O O   . HOH L 3 .   ? -3.767  -17.526 -83.878  1.00 31.16  ? 1027 HOH D O   1 
HETATM 16183 O O   . HOH L 3 .   ? -15.580 -27.028 -79.610  1.00 31.20  ? 1028 HOH D O   1 
HETATM 16184 O O   . HOH L 3 .   ? -18.546 17.496  -37.929  1.00 39.17  ? 1029 HOH D O   1 
HETATM 16185 O O   . HOH L 3 .   ? -35.154 12.787  -48.360  1.00 30.44  ? 1030 HOH D O   1 
HETATM 16186 O O   . HOH L 3 .   ? -18.945 25.802  -60.665  1.00 28.17  ? 1031 HOH D O   1 
HETATM 16187 O O   . HOH L 3 .   ? -34.962 -5.059  -82.286  1.00 27.08  ? 1032 HOH D O   1 
HETATM 16188 O O   . HOH L 3 .   ? -17.614 25.909  -52.569  1.00 47.84  ? 1033 HOH D O   1 
HETATM 16189 O O   . HOH L 3 .   ? -31.439 7.131   -44.538  1.00 28.81  ? 1034 HOH D O   1 
HETATM 16190 O O   . HOH L 3 .   ? -0.360  21.466  -58.400  1.00 27.51  ? 1035 HOH D O   1 
HETATM 16191 O O   . HOH L 3 .   ? -42.891 6.035   -71.235  1.00 46.64  ? 1036 HOH D O   1 
HETATM 16192 O O   . HOH L 3 .   ? -18.199 -13.010 -59.500  1.00 67.53  ? 1037 HOH D O   1 
HETATM 16193 O O   . HOH L 3 .   ? -19.660 -29.893 -70.354  1.00 58.13  ? 1038 HOH D O   1 
HETATM 16194 O O   . HOH L 3 .   ? -11.544 22.014  -44.488  1.00 48.66  ? 1039 HOH D O   1 
HETATM 16195 O O   . HOH L 3 .   ? -0.953  20.494  -48.705  1.00 47.82  ? 1040 HOH D O   1 
HETATM 16196 O O   . HOH L 3 .   ? -4.392  15.082  -73.183  1.00 33.49  ? 1041 HOH D O   1 
HETATM 16197 O O   . HOH L 3 .   ? -17.140 -27.986 -95.518  1.00 35.65  ? 1042 HOH D O   1 
HETATM 16198 O O   . HOH L 3 .   ? -41.305 9.198   -72.882  1.00 26.74  ? 1043 HOH D O   1 
HETATM 16199 O O   . HOH L 3 .   ? -32.506 12.480  -68.928  1.00 39.81  ? 1044 HOH D O   1 
HETATM 16200 O O   . HOH L 3 .   ? -6.450  -14.869 -49.533  1.00 27.45  ? 1045 HOH D O   1 
HETATM 16201 O O   . HOH L 3 .   ? -2.577  19.093  -55.578  1.00 31.65  ? 1046 HOH D O   1 
HETATM 16202 O O   . HOH L 3 .   ? -45.801 -22.383 -66.479  1.00 30.43  ? 1047 HOH D O   1 
HETATM 16203 O O   . HOH L 3 .   ? 7.474   -13.998 -84.814  1.00 36.71  ? 1048 HOH D O   1 
HETATM 16204 O O   . HOH L 3 .   ? -27.346 -13.899 -88.432  1.00 28.22  ? 1049 HOH D O   1 
HETATM 16205 O O   . HOH L 3 .   ? -1.836  19.268  -52.103  1.00 37.25  ? 1050 HOH D O   1 
HETATM 16206 O O   . HOH L 3 .   ? -12.100 -21.279 -91.979  1.00 45.44  ? 1051 HOH D O   1 
HETATM 16207 O O   . HOH L 3 .   ? -24.369 -17.773 -51.880  1.00 39.48  ? 1052 HOH D O   1 
HETATM 16208 O O   . HOH L 3 .   ? -33.708 3.044   -54.650  1.00 40.32  ? 1053 HOH D O   1 
HETATM 16209 O O   . HOH L 3 .   ? -26.375 20.962  -53.295  1.00 37.23  ? 1054 HOH D O   1 
HETATM 16210 O O   . HOH L 3 .   ? -3.914  -5.199  -44.950  1.00 12.13  ? 1055 HOH D O   1 
HETATM 16211 O O   . HOH L 3 .   ? -34.884 -3.751  -53.195  1.00 57.05  ? 1056 HOH D O   1 
HETATM 16212 O O   . HOH L 3 .   ? 2.860   -20.088 -75.865  1.00 37.40  ? 1057 HOH D O   1 
HETATM 16213 O O   . HOH L 3 .   ? -4.695  -13.991 -47.739  1.00 44.79  ? 1058 HOH D O   1 
HETATM 16214 O O   . HOH L 3 .   ? -19.037 23.356  -54.644  1.00 30.97  ? 1059 HOH D O   1 
HETATM 16215 O O   . HOH L 3 .   ? -10.134 -14.438 -50.049  1.00 44.05  ? 1060 HOH D O   1 
HETATM 16216 O O   . HOH L 3 .   ? -37.353 -6.912  -82.955  1.00 39.85  ? 1061 HOH D O   1 
HETATM 16217 O O   . HOH L 3 .   ? -36.218 -2.829  -81.811  1.00 26.50  ? 1062 HOH D O   1 
HETATM 16218 O O   . HOH L 3 .   ? -25.982 1.106   -88.312  1.00 55.70  ? 1063 HOH D O   1 
HETATM 16219 O O   . HOH L 3 .   ? -30.673 13.873  -43.321  1.00 43.69  ? 1064 HOH D O   1 
HETATM 16220 O O   . HOH L 3 .   ? -14.482 20.547  -38.593  1.00 54.39  ? 1065 HOH D O   1 
HETATM 16221 O O   . HOH L 3 .   ? -25.183 -27.625 -79.670  1.00 47.94  ? 1066 HOH D O   1 
HETATM 16222 O O   . HOH L 3 .   ? -32.117 4.348   -41.507  1.00 39.26  ? 1067 HOH D O   1 
HETATM 16223 O O   . HOH L 3 .   ? -2.312  -7.645  -44.664  1.00 20.78  ? 1068 HOH D O   1 
HETATM 16224 O O   . HOH L 3 .   ? -32.249 15.023  -45.225  1.00 29.39  ? 1069 HOH D O   1 
HETATM 16225 O O   . HOH L 3 .   ? 2.421   22.832  -66.829  1.00 44.27  ? 1070 HOH D O   1 
HETATM 16226 O O   . HOH L 3 .   ? -32.153 2.183   -83.401  1.00 24.29  ? 1071 HOH D O   1 
HETATM 16227 O O   . HOH L 3 .   ? -24.209 10.788  -33.885  1.00 24.14  ? 1072 HOH D O   1 
HETATM 16228 O O   . HOH L 3 .   ? -44.686 -15.343 -51.790  1.00 38.67  ? 1073 HOH D O   1 
HETATM 16229 O O   . HOH L 3 .   ? -44.011 -23.977 -52.574  1.00 47.76  ? 1074 HOH D O   1 
HETATM 16230 O O   . HOH L 3 .   ? -4.852  -9.312  -93.472  1.00 29.58  ? 1075 HOH D O   1 
HETATM 16231 O O   . HOH L 3 .   ? -34.348 11.660  -70.710  1.00 30.99  ? 1076 HOH D O   1 
HETATM 16232 O O   . HOH L 3 .   ? -22.273 8.433   -29.502  1.00 36.55  ? 1077 HOH D O   1 
HETATM 16233 O O   . HOH L 3 .   ? 0.220   -7.590  -44.779  1.00 21.24  ? 1078 HOH D O   1 
HETATM 16234 O O   . HOH L 3 .   ? -30.472 -1.362  -85.381  1.00 14.18  ? 1079 HOH D O   1 
HETATM 16235 O O   . HOH L 3 .   ? -31.165 4.759   -85.330  1.00 33.46  ? 1080 HOH D O   1 
HETATM 16236 O O   . HOH L 3 .   ? -9.418  -26.398 -69.804  1.00 54.29  ? 1081 HOH D O   1 
HETATM 16237 O O   . HOH L 3 .   ? -7.532  -15.358 -53.997  1.00 36.36  ? 1082 HOH D O   1 
HETATM 16238 O O   . HOH L 3 .   ? -3.372  -0.920  -44.043  1.00 74.39  ? 1083 HOH D O   1 
HETATM 16239 O O   . HOH L 3 .   ? -34.720 -27.341 -54.540  1.00 36.61  ? 1084 HOH D O   1 
HETATM 16240 O O   . HOH L 3 .   ? -13.272 -28.447 -78.489  1.00 31.83  ? 1085 HOH D O   1 
HETATM 16241 O O   . HOH L 3 .   ? -28.302 -4.634  -47.747  1.00 17.39  ? 1086 HOH D O   1 
HETATM 16242 O O   . HOH L 3 .   ? -45.954 -19.751 -51.073  1.00 43.74  ? 1087 HOH D O   1 
HETATM 16243 O O   . HOH L 3 .   ? -43.363 -24.210 -69.787  1.00 45.14  ? 1088 HOH D O   1 
HETATM 16244 O O   . HOH L 3 .   ? -37.975 -16.531 -77.415  1.00 22.09  ? 1089 HOH D O   1 
HETATM 16245 O O   . HOH L 3 .   ? -45.446 -10.132 -69.559  1.00 31.41  ? 1090 HOH D O   1 
HETATM 16246 O O   . HOH L 3 .   ? -40.159 7.069   -47.017  1.00 35.33  ? 1091 HOH D O   1 
HETATM 16247 O O   . HOH L 3 .   ? -17.780 1.961   -37.938  1.00 37.51  ? 1092 HOH D O   1 
HETATM 16248 O O   . HOH L 3 .   ? -11.620 -14.439 -68.575  1.00 30.49  ? 1093 HOH D O   1 
HETATM 16249 O O   . HOH L 3 .   ? -48.139 -3.549  -74.932  1.00 29.99  ? 1094 HOH D O   1 
HETATM 16250 O O   . HOH L 3 .   ? -32.959 6.772   -35.445  1.00 22.56  ? 1095 HOH D O   1 
HETATM 16251 O O   . HOH L 3 .   ? -30.748 11.164  -41.761  1.00 15.90  ? 1096 HOH D O   1 
HETATM 16252 O O   . HOH L 3 .   ? 2.256   -5.649  -44.979  1.00 20.14  ? 1097 HOH D O   1 
HETATM 16253 O O   . HOH L 3 .   ? -35.187 15.828  -47.434  1.00 25.19  ? 1098 HOH D O   1 
HETATM 16254 O O   . HOH L 3 .   ? -32.309 9.085   -42.737  1.00 16.91  ? 1099 HOH D O   1 
HETATM 16255 O O   . HOH L 3 .   ? -3.660  26.617  -46.668  1.00 53.11  ? 1100 HOH D O   1 
HETATM 16256 O O   . HOH L 3 .   ? -39.487 -2.379  -82.368  1.00 29.59  ? 1101 HOH D O   1 
HETATM 16257 O O   . HOH L 3 .   ? -31.986 0.076   -84.835  1.00 26.75  ? 1102 HOH D O   1 
HETATM 16258 O O   . HOH L 3 .   ? -5.970  -16.778 -51.445  1.00 57.31  ? 1103 HOH D O   1 
HETATM 16259 O O   . HOH L 3 .   ? -45.123 -17.625 -49.601  1.00 39.08  ? 1104 HOH D O   1 
HETATM 16260 O O   . HOH L 3 .   ? -32.296 3.152   -36.806  1.00 24.24  ? 1105 HOH D O   1 
HETATM 16261 O O   . HOH L 3 .   ? -27.015 -33.459 -75.862  1.00 53.89  ? 1106 HOH D O   1 
HETATM 16262 O O   . HOH L 3 .   ? -47.157 -1.128  -76.315  1.00 45.55  ? 1107 HOH D O   1 
# 
