data_8R26
# 
_entry.id   8R26 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R26         pdb_00008r26 10.2210/pdb8r26/pdb 
WWPDB D_1292134432 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R26 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              rolf.hilgenfeld@uni-luebeck.de 
_pdbx_contact_author.name_first         Hilgenfeld 
_pdbx_contact_author.name_last          Rolf 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8850-2977 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ibrahim, M.'    1 0000-0002-1431-9755 
'Sun, X.'        2 0000-0002-2761-2862 
'Hilgenfeld, R.' 3 0000-0001-8850-2977 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'SARS-CoV-2 Mpro (Omicron,P132H) in complex with alpha-ketoamide 13b-K at pH 8.5' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ibrahim, M.'    1 0000-0002-1431-9755 
primary 'Hilgenfeld, R.' 2 0000-0001-8850-2977 
primary 'Sun, X.'        3 0000-0002-2761-2862 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '3C-like proteinase nsp5' 33866.578 4   3.4.22.69 ? ? ? 
2 non-polymer syn 
;~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate
;
595.687   4   ?         ? ? ? 
3 non-polymer syn 'CHLORIDE ION' 35.453    3   ?         ? ? ? 
4 water       nat water 18.015    365 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRHNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRHNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_strand_id                 A,B,D,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate
;
O6K 
3 'CHLORIDE ION' CL  
4 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLY n 
1 3   PHE n 
1 4   ARG n 
1 5   LYS n 
1 6   MET n 
1 7   ALA n 
1 8   PHE n 
1 9   PRO n 
1 10  SER n 
1 11  GLY n 
1 12  LYS n 
1 13  VAL n 
1 14  GLU n 
1 15  GLY n 
1 16  CYS n 
1 17  MET n 
1 18  VAL n 
1 19  GLN n 
1 20  VAL n 
1 21  THR n 
1 22  CYS n 
1 23  GLY n 
1 24  THR n 
1 25  THR n 
1 26  THR n 
1 27  LEU n 
1 28  ASN n 
1 29  GLY n 
1 30  LEU n 
1 31  TRP n 
1 32  LEU n 
1 33  ASP n 
1 34  ASP n 
1 35  VAL n 
1 36  VAL n 
1 37  TYR n 
1 38  CYS n 
1 39  PRO n 
1 40  ARG n 
1 41  HIS n 
1 42  VAL n 
1 43  ILE n 
1 44  CYS n 
1 45  THR n 
1 46  SER n 
1 47  GLU n 
1 48  ASP n 
1 49  MET n 
1 50  LEU n 
1 51  ASN n 
1 52  PRO n 
1 53  ASN n 
1 54  TYR n 
1 55  GLU n 
1 56  ASP n 
1 57  LEU n 
1 58  LEU n 
1 59  ILE n 
1 60  ARG n 
1 61  LYS n 
1 62  SER n 
1 63  ASN n 
1 64  HIS n 
1 65  ASN n 
1 66  PHE n 
1 67  LEU n 
1 68  VAL n 
1 69  GLN n 
1 70  ALA n 
1 71  GLY n 
1 72  ASN n 
1 73  VAL n 
1 74  GLN n 
1 75  LEU n 
1 76  ARG n 
1 77  VAL n 
1 78  ILE n 
1 79  GLY n 
1 80  HIS n 
1 81  SER n 
1 82  MET n 
1 83  GLN n 
1 84  ASN n 
1 85  CYS n 
1 86  VAL n 
1 87  LEU n 
1 88  LYS n 
1 89  LEU n 
1 90  LYS n 
1 91  VAL n 
1 92  ASP n 
1 93  THR n 
1 94  ALA n 
1 95  ASN n 
1 96  PRO n 
1 97  LYS n 
1 98  THR n 
1 99  PRO n 
1 100 LYS n 
1 101 TYR n 
1 102 LYS n 
1 103 PHE n 
1 104 VAL n 
1 105 ARG n 
1 106 ILE n 
1 107 GLN n 
1 108 PRO n 
1 109 GLY n 
1 110 GLN n 
1 111 THR n 
1 112 PHE n 
1 113 SER n 
1 114 VAL n 
1 115 LEU n 
1 116 ALA n 
1 117 CYS n 
1 118 TYR n 
1 119 ASN n 
1 120 GLY n 
1 121 SER n 
1 122 PRO n 
1 123 SER n 
1 124 GLY n 
1 125 VAL n 
1 126 TYR n 
1 127 GLN n 
1 128 CYS n 
1 129 ALA n 
1 130 MET n 
1 131 ARG n 
1 132 HIS n 
1 133 ASN n 
1 134 PHE n 
1 135 THR n 
1 136 ILE n 
1 137 LYS n 
1 138 GLY n 
1 139 SER n 
1 140 PHE n 
1 141 LEU n 
1 142 ASN n 
1 143 GLY n 
1 144 SER n 
1 145 CYS n 
1 146 GLY n 
1 147 SER n 
1 148 VAL n 
1 149 GLY n 
1 150 PHE n 
1 151 ASN n 
1 152 ILE n 
1 153 ASP n 
1 154 TYR n 
1 155 ASP n 
1 156 CYS n 
1 157 VAL n 
1 158 SER n 
1 159 PHE n 
1 160 CYS n 
1 161 TYR n 
1 162 MET n 
1 163 HIS n 
1 164 HIS n 
1 165 MET n 
1 166 GLU n 
1 167 LEU n 
1 168 PRO n 
1 169 THR n 
1 170 GLY n 
1 171 VAL n 
1 172 HIS n 
1 173 ALA n 
1 174 GLY n 
1 175 THR n 
1 176 ASP n 
1 177 LEU n 
1 178 GLU n 
1 179 GLY n 
1 180 ASN n 
1 181 PHE n 
1 182 TYR n 
1 183 GLY n 
1 184 PRO n 
1 185 PHE n 
1 186 VAL n 
1 187 ASP n 
1 188 ARG n 
1 189 GLN n 
1 190 THR n 
1 191 ALA n 
1 192 GLN n 
1 193 ALA n 
1 194 ALA n 
1 195 GLY n 
1 196 THR n 
1 197 ASP n 
1 198 THR n 
1 199 THR n 
1 200 ILE n 
1 201 THR n 
1 202 VAL n 
1 203 ASN n 
1 204 VAL n 
1 205 LEU n 
1 206 ALA n 
1 207 TRP n 
1 208 LEU n 
1 209 TYR n 
1 210 ALA n 
1 211 ALA n 
1 212 VAL n 
1 213 ILE n 
1 214 ASN n 
1 215 GLY n 
1 216 ASP n 
1 217 ARG n 
1 218 TRP n 
1 219 PHE n 
1 220 LEU n 
1 221 ASN n 
1 222 ARG n 
1 223 PHE n 
1 224 THR n 
1 225 THR n 
1 226 THR n 
1 227 LEU n 
1 228 ASN n 
1 229 ASP n 
1 230 PHE n 
1 231 ASN n 
1 232 LEU n 
1 233 VAL n 
1 234 ALA n 
1 235 MET n 
1 236 LYS n 
1 237 TYR n 
1 238 ASN n 
1 239 TYR n 
1 240 GLU n 
1 241 PRO n 
1 242 LEU n 
1 243 THR n 
1 244 GLN n 
1 245 ASP n 
1 246 HIS n 
1 247 VAL n 
1 248 ASP n 
1 249 ILE n 
1 250 LEU n 
1 251 GLY n 
1 252 PRO n 
1 253 LEU n 
1 254 SER n 
1 255 ALA n 
1 256 GLN n 
1 257 THR n 
1 258 GLY n 
1 259 ILE n 
1 260 ALA n 
1 261 VAL n 
1 262 LEU n 
1 263 ASP n 
1 264 MET n 
1 265 CYS n 
1 266 ALA n 
1 267 SER n 
1 268 LEU n 
1 269 LYS n 
1 270 GLU n 
1 271 LEU n 
1 272 LEU n 
1 273 GLN n 
1 274 ASN n 
1 275 GLY n 
1 276 MET n 
1 277 ASN n 
1 278 GLY n 
1 279 ARG n 
1 280 THR n 
1 281 ILE n 
1 282 LEU n 
1 283 GLY n 
1 284 SER n 
1 285 ALA n 
1 286 LEU n 
1 287 LEU n 
1 288 GLU n 
1 289 ASP n 
1 290 GLU n 
1 291 PHE n 
1 292 THR n 
1 293 PRO n 
1 294 PHE n 
1 295 ASP n 
1 296 VAL n 
1 297 VAL n 
1 298 ARG n 
1 299 GLN n 
1 300 CYS n 
1 301 SER n 
1 302 GLY n 
1 303 VAL n 
1 304 THR n 
1 305 PHE n 
1 306 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   306 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ?                                                     'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE ?                                                     'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                                                     'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                                     'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION' ?                                                     'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE ?                                                     'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                                                     'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                                     'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE ?                                                     'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE ?                                                     'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER ?                                                     'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                                                     'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE ?                                                     'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE ?                                                     'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE ?                                                     'C5 H11 N O2 S'  149.211 
O6K non-polymer         . 
;~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate
;
'(S,S,S)-13b; 13b-K; ketoamide inhibitor 13b (bound)' 'C31 H41 N5 O7'  595.687 
PHE 'L-peptide linking' y PHENYLALANINE ?                                                     'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE ?                                                     'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE ?                                                     'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE ?                                                     'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                                                     'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE ?                                                     'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE ?                                                     'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1   1   SER SER A . n 
A 1 2   GLY 2   2   2   GLY GLY A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   MET 6   6   6   MET MET A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   PRO 9   9   9   PRO PRO A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  LYS 12  12  12  LYS LYS A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  MET 17  17  17  MET MET A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  GLN 19  19  19  GLN GLN A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  THR 21  21  21  THR THR A . n 
A 1 22  CYS 22  22  22  CYS CYS A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ASN 28  28  28  ASN ASN A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  TRP 31  31  31  TRP TRP A . n 
A 1 32  LEU 32  32  32  LEU LEU A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  VAL 35  35  35  VAL VAL A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  CYS 38  38  38  CYS CYS A . n 
A 1 39  PRO 39  39  39  PRO PRO A . n 
A 1 40  ARG 40  40  40  ARG ARG A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  CYS 44  44  44  CYS CYS A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  GLU 47  47  47  GLU GLU A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  MET 49  49  49  MET MET A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  ASN 51  51  51  ASN ASN A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  TYR 54  54  54  TYR TYR A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  ASP 56  56  56  ASP ASP A . n 
A 1 57  LEU 57  57  57  LEU LEU A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ARG 60  60  60  ARG ARG A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  GLN 69  69  69  GLN GLN A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ASN 72  72  72  ASN ASN A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  GLN 74  74  74  GLN GLN A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  ILE 78  78  78  ILE ILE A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  SER 81  81  81  SER SER A . n 
A 1 82  MET 82  82  82  MET MET A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ASN 84  84  84  ASN ASN A . n 
A 1 85  CYS 85  85  85  CYS CYS A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  LYS 90  90  90  LYS LYS A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  ASN 95  95  95  ASN ASN A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 ARG 105 105 105 ARG ARG A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 GLN 107 107 107 GLN GLN A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 SER 113 113 113 SER SER A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 CYS 117 117 117 CYS CYS A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 ASN 119 119 119 ASN ASN A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 GLN 127 127 127 GLN GLN A . n 
A 1 128 CYS 128 128 128 CYS CYS A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 HIS 132 132 132 HIS HIS A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 PHE 134 134 134 PHE PHE A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 ILE 136 136 136 ILE ILE A . n 
A 1 137 LYS 137 137 137 LYS LYS A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 PHE 140 140 140 PHE PHE A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ASN 142 142 142 ASN ASN A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 CYS 145 145 145 CYS CYS A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 ASN 151 151 151 ASN ASN A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ASP 153 153 153 ASP ASP A . n 
A 1 154 TYR 154 154 154 TYR TYR A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 CYS 160 160 160 CYS CYS A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 MET 162 162 162 MET MET A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 MET 165 165 165 MET MET A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 GLU 178 178 178 GLU GLU A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 ASP 187 187 187 ASP ASP A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 GLN 192 192 192 GLN GLN A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 ASP 197 197 197 ASP ASP A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 ILE 200 200 200 ILE ILE A . n 
A 1 201 THR 201 201 201 THR THR A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 TYR 209 209 209 TYR TYR A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ILE 213 213 213 ILE ILE A . n 
A 1 214 ASN 214 214 214 ASN ASN A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 TRP 218 218 218 TRP TRP A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASN 221 221 221 ASN ASN A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 MET 235 235 235 MET MET A . n 
A 1 236 LYS 236 236 236 LYS LYS A . n 
A 1 237 TYR 237 237 237 TYR TYR A . n 
A 1 238 ASN 238 238 238 ASN ASN A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 GLN 244 244 244 GLN GLN A . n 
A 1 245 ASP 245 245 245 ASP ASP A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 GLN 256 256 256 GLN GLN A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 ASP 263 263 263 ASP ASP A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 CYS 265 265 265 CYS CYS A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 LYS 269 269 269 LYS LYS A . n 
A 1 270 GLU 270 270 270 GLU GLU A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 ASN 274 274 274 ASN ASN A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 MET 276 276 276 MET MET A . n 
A 1 277 ASN 277 277 277 ASN ASN A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 ARG 279 279 279 ARG ARG A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 ILE 281 281 281 ILE ILE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 SER 284 284 284 SER SER A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 ASP 289 289 289 ASP ASP A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 PRO 293 293 293 PRO PRO A . n 
A 1 294 PHE 294 294 294 PHE PHE A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 GLN 299 299 299 GLN GLN A . n 
A 1 300 CYS 300 300 300 CYS CYS A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 GLN 306 306 ?   ?   ?   A . n 
B 1 1   SER 1   1   1   SER SER B . n 
B 1 2   GLY 2   2   2   GLY GLY B . n 
B 1 3   PHE 3   3   3   PHE PHE B . n 
B 1 4   ARG 4   4   4   ARG ARG B . n 
B 1 5   LYS 5   5   5   LYS LYS B . n 
B 1 6   MET 6   6   6   MET MET B . n 
B 1 7   ALA 7   7   7   ALA ALA B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   PRO 9   9   9   PRO PRO B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  GLY 11  11  11  GLY GLY B . n 
B 1 12  LYS 12  12  12  LYS LYS B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  GLU 14  14  14  GLU GLU B . n 
B 1 15  GLY 15  15  15  GLY GLY B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  MET 17  17  17  MET MET B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  GLN 19  19  19  GLN GLN B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  THR 21  21  21  THR THR B . n 
B 1 22  CYS 22  22  22  CYS CYS B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  THR 24  24  24  THR THR B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ASN 28  28  28  ASN ASN B . n 
B 1 29  GLY 29  29  29  GLY GLY B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  TRP 31  31  31  TRP TRP B . n 
B 1 32  LEU 32  32  32  LEU LEU B . n 
B 1 33  ASP 33  33  33  ASP ASP B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  VAL 35  35  35  VAL VAL B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  TYR 37  37  37  TYR TYR B . n 
B 1 38  CYS 38  38  38  CYS CYS B . n 
B 1 39  PRO 39  39  39  PRO PRO B . n 
B 1 40  ARG 40  40  40  ARG ARG B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  CYS 44  44  44  CYS CYS B . n 
B 1 45  THR 45  45  45  THR THR B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  GLU 47  47  47  GLU GLU B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  MET 49  49  49  MET MET B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  ASN 51  51  51  ASN ASN B . n 
B 1 52  PRO 52  52  52  PRO PRO B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  TYR 54  54  54  TYR TYR B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  ASP 56  56  56  ASP ASP B . n 
B 1 57  LEU 57  57  57  LEU LEU B . n 
B 1 58  LEU 58  58  58  LEU LEU B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  ARG 60  60  60  ARG ARG B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  SER 62  62  62  SER SER B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  HIS 64  64  64  HIS HIS B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  LEU 67  67  67  LEU LEU B . n 
B 1 68  VAL 68  68  68  VAL VAL B . n 
B 1 69  GLN 69  69  69  GLN GLN B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  ASN 72  72  72  ASN ASN B . n 
B 1 73  VAL 73  73  73  VAL VAL B . n 
B 1 74  GLN 74  74  74  GLN GLN B . n 
B 1 75  LEU 75  75  75  LEU LEU B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  ILE 78  78  78  ILE ILE B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  SER 81  81  81  SER SER B . n 
B 1 82  MET 82  82  82  MET MET B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ASN 84  84  84  ASN ASN B . n 
B 1 85  CYS 85  85  85  CYS CYS B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  LEU 87  87  87  LEU LEU B . n 
B 1 88  LYS 88  88  88  LYS LYS B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  LYS 90  90  90  LYS LYS B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  ALA 94  94  94  ALA ALA B . n 
B 1 95  ASN 95  95  95  ASN ASN B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  LYS 97  97  97  LYS LYS B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 LYS 100 100 100 LYS LYS B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 ARG 105 105 105 ARG ARG B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 GLN 107 107 107 GLN GLN B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 SER 113 113 113 SER SER B . n 
B 1 114 VAL 114 114 114 VAL VAL B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 ALA 116 116 116 ALA ALA B . n 
B 1 117 CYS 117 117 117 CYS CYS B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 ASN 119 119 119 ASN ASN B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 SER 121 121 121 SER SER B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 GLN 127 127 127 GLN GLN B . n 
B 1 128 CYS 128 128 128 CYS CYS B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 HIS 132 132 132 HIS HIS B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 PHE 134 134 134 PHE PHE B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 ILE 136 136 136 ILE ILE B . n 
B 1 137 LYS 137 137 137 LYS LYS B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 PHE 140 140 140 PHE PHE B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 ASN 142 142 142 ASN ASN B . n 
B 1 143 GLY 143 143 143 GLY GLY B . n 
B 1 144 SER 144 144 144 SER SER B . n 
B 1 145 CYS 145 145 145 CYS CYS B . n 
B 1 146 GLY 146 146 146 GLY GLY B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 ASN 151 151 151 ASN ASN B . n 
B 1 152 ILE 152 152 152 ILE ILE B . n 
B 1 153 ASP 153 153 153 ASP ASP B . n 
B 1 154 TYR 154 154 154 TYR TYR B . n 
B 1 155 ASP 155 155 155 ASP ASP B . n 
B 1 156 CYS 156 156 156 CYS CYS B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 SER 158 158 158 SER SER B . n 
B 1 159 PHE 159 159 159 PHE PHE B . n 
B 1 160 CYS 160 160 160 CYS CYS B . n 
B 1 161 TYR 161 161 161 TYR TYR B . n 
B 1 162 MET 162 162 162 MET MET B . n 
B 1 163 HIS 163 163 163 HIS HIS B . n 
B 1 164 HIS 164 164 164 HIS HIS B . n 
B 1 165 MET 165 165 165 MET MET B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 VAL 171 171 171 VAL VAL B . n 
B 1 172 HIS 172 172 172 HIS HIS B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 GLY 174 174 174 GLY GLY B . n 
B 1 175 THR 175 175 175 THR THR B . n 
B 1 176 ASP 176 176 176 ASP ASP B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 GLU 178 178 178 GLU GLU B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 ASN 180 180 180 ASN ASN B . n 
B 1 181 PHE 181 181 181 PHE PHE B . n 
B 1 182 TYR 182 182 182 TYR TYR B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 PHE 185 185 185 PHE PHE B . n 
B 1 186 VAL 186 186 186 VAL VAL B . n 
B 1 187 ASP 187 187 187 ASP ASP B . n 
B 1 188 ARG 188 188 188 ARG ARG B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 THR 190 190 190 THR THR B . n 
B 1 191 ALA 191 191 191 ALA ALA B . n 
B 1 192 GLN 192 192 192 GLN GLN B . n 
B 1 193 ALA 193 193 193 ALA ALA B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 ASP 197 197 197 ASP ASP B . n 
B 1 198 THR 198 198 198 THR THR B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 ILE 200 200 200 ILE ILE B . n 
B 1 201 THR 201 201 201 THR THR B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 ASN 203 203 203 ASN ASN B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 ALA 206 206 206 ALA ALA B . n 
B 1 207 TRP 207 207 207 TRP TRP B . n 
B 1 208 LEU 208 208 208 LEU LEU B . n 
B 1 209 TYR 209 209 209 TYR TYR B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ILE 213 213 213 ILE ILE B . n 
B 1 214 ASN 214 214 214 ASN ASN B . n 
B 1 215 GLY 215 215 215 GLY GLY B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 TRP 218 218 218 TRP TRP B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASN 221 221 221 ASN ASN B . n 
B 1 222 ARG 222 222 222 ARG ARG B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 ASN 228 228 228 ASN ASN B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 PHE 230 230 230 PHE PHE B . n 
B 1 231 ASN 231 231 231 ASN ASN B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 VAL 233 233 233 VAL VAL B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 MET 235 235 235 MET MET B . n 
B 1 236 LYS 236 236 236 LYS LYS B . n 
B 1 237 TYR 237 237 237 TYR TYR B . n 
B 1 238 ASN 238 238 238 ASN ASN B . n 
B 1 239 TYR 239 239 239 TYR TYR B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 PRO 241 241 241 PRO PRO B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 GLN 244 244 244 GLN GLN B . n 
B 1 245 ASP 245 245 245 ASP ASP B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 ASP 248 248 248 ASP ASP B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 PRO 252 252 252 PRO PRO B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 GLN 256 256 256 GLN GLN B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 ILE 259 259 259 ILE ILE B . n 
B 1 260 ALA 260 260 260 ALA ALA B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 LEU 262 262 262 LEU LEU B . n 
B 1 263 ASP 263 263 263 ASP ASP B . n 
B 1 264 MET 264 264 264 MET MET B . n 
B 1 265 CYS 265 265 265 CYS CYS B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 LYS 269 269 269 LYS LYS B . n 
B 1 270 GLU 270 270 270 GLU GLU B . n 
B 1 271 LEU 271 271 271 LEU LEU B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 GLN 273 273 273 GLN GLN B . n 
B 1 274 ASN 274 274 274 ASN ASN B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 MET 276 276 276 MET MET B . n 
B 1 277 ASN 277 277 277 ASN ASN B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 ARG 279 279 279 ARG ARG B . n 
B 1 280 THR 280 280 280 THR THR B . n 
B 1 281 ILE 281 281 281 ILE ILE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 SER 284 284 284 SER SER B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 LEU 286 286 286 LEU LEU B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 ASP 289 289 289 ASP ASP B . n 
B 1 290 GLU 290 290 290 GLU GLU B . n 
B 1 291 PHE 291 291 291 PHE PHE B . n 
B 1 292 THR 292 292 292 THR THR B . n 
B 1 293 PRO 293 293 293 PRO PRO B . n 
B 1 294 PHE 294 294 294 PHE PHE B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 GLN 299 299 299 GLN GLN B . n 
B 1 300 CYS 300 300 300 CYS CYS B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 GLY 302 302 302 GLY GLY B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 THR 304 304 304 THR THR B . n 
B 1 305 PHE 305 305 305 PHE PHE B . n 
B 1 306 GLN 306 306 ?   ?   ?   B . n 
C 1 1   SER 1   1   1   SER SER D . n 
C 1 2   GLY 2   2   2   GLY GLY D . n 
C 1 3   PHE 3   3   3   PHE PHE D . n 
C 1 4   ARG 4   4   4   ARG ARG D . n 
C 1 5   LYS 5   5   5   LYS LYS D . n 
C 1 6   MET 6   6   6   MET MET D . n 
C 1 7   ALA 7   7   7   ALA ALA D . n 
C 1 8   PHE 8   8   8   PHE PHE D . n 
C 1 9   PRO 9   9   9   PRO PRO D . n 
C 1 10  SER 10  10  10  SER SER D . n 
C 1 11  GLY 11  11  11  GLY GLY D . n 
C 1 12  LYS 12  12  12  LYS LYS D . n 
C 1 13  VAL 13  13  13  VAL VAL D . n 
C 1 14  GLU 14  14  14  GLU GLU D . n 
C 1 15  GLY 15  15  15  GLY GLY D . n 
C 1 16  CYS 16  16  16  CYS CYS D . n 
C 1 17  MET 17  17  17  MET MET D . n 
C 1 18  VAL 18  18  18  VAL VAL D . n 
C 1 19  GLN 19  19  19  GLN GLN D . n 
C 1 20  VAL 20  20  20  VAL VAL D . n 
C 1 21  THR 21  21  21  THR THR D . n 
C 1 22  CYS 22  22  22  CYS CYS D . n 
C 1 23  GLY 23  23  23  GLY GLY D . n 
C 1 24  THR 24  24  24  THR THR D . n 
C 1 25  THR 25  25  25  THR THR D . n 
C 1 26  THR 26  26  26  THR THR D . n 
C 1 27  LEU 27  27  27  LEU LEU D . n 
C 1 28  ASN 28  28  28  ASN ASN D . n 
C 1 29  GLY 29  29  29  GLY GLY D . n 
C 1 30  LEU 30  30  30  LEU LEU D . n 
C 1 31  TRP 31  31  31  TRP TRP D . n 
C 1 32  LEU 32  32  32  LEU LEU D . n 
C 1 33  ASP 33  33  33  ASP ASP D . n 
C 1 34  ASP 34  34  34  ASP ASP D . n 
C 1 35  VAL 35  35  35  VAL VAL D . n 
C 1 36  VAL 36  36  36  VAL VAL D . n 
C 1 37  TYR 37  37  37  TYR TYR D . n 
C 1 38  CYS 38  38  38  CYS CYS D . n 
C 1 39  PRO 39  39  39  PRO PRO D . n 
C 1 40  ARG 40  40  40  ARG ARG D . n 
C 1 41  HIS 41  41  41  HIS HIS D . n 
C 1 42  VAL 42  42  42  VAL VAL D . n 
C 1 43  ILE 43  43  43  ILE ILE D . n 
C 1 44  CYS 44  44  44  CYS CYS D . n 
C 1 45  THR 45  45  45  THR THR D . n 
C 1 46  SER 46  46  46  SER SER D . n 
C 1 47  GLU 47  47  47  GLU GLU D . n 
C 1 48  ASP 48  48  48  ASP ASP D . n 
C 1 49  MET 49  49  49  MET MET D . n 
C 1 50  LEU 50  50  50  LEU LEU D . n 
C 1 51  ASN 51  51  51  ASN ASN D . n 
C 1 52  PRO 52  52  52  PRO PRO D . n 
C 1 53  ASN 53  53  53  ASN ASN D . n 
C 1 54  TYR 54  54  54  TYR TYR D . n 
C 1 55  GLU 55  55  55  GLU GLU D . n 
C 1 56  ASP 56  56  56  ASP ASP D . n 
C 1 57  LEU 57  57  57  LEU LEU D . n 
C 1 58  LEU 58  58  58  LEU LEU D . n 
C 1 59  ILE 59  59  59  ILE ILE D . n 
C 1 60  ARG 60  60  60  ARG ARG D . n 
C 1 61  LYS 61  61  61  LYS LYS D . n 
C 1 62  SER 62  62  62  SER SER D . n 
C 1 63  ASN 63  63  63  ASN ASN D . n 
C 1 64  HIS 64  64  64  HIS HIS D . n 
C 1 65  ASN 65  65  65  ASN ASN D . n 
C 1 66  PHE 66  66  66  PHE PHE D . n 
C 1 67  LEU 67  67  67  LEU LEU D . n 
C 1 68  VAL 68  68  68  VAL VAL D . n 
C 1 69  GLN 69  69  69  GLN GLN D . n 
C 1 70  ALA 70  70  70  ALA ALA D . n 
C 1 71  GLY 71  71  71  GLY GLY D . n 
C 1 72  ASN 72  72  72  ASN ASN D . n 
C 1 73  VAL 73  73  73  VAL VAL D . n 
C 1 74  GLN 74  74  74  GLN GLN D . n 
C 1 75  LEU 75  75  75  LEU LEU D . n 
C 1 76  ARG 76  76  76  ARG ARG D . n 
C 1 77  VAL 77  77  77  VAL VAL D . n 
C 1 78  ILE 78  78  78  ILE ILE D . n 
C 1 79  GLY 79  79  79  GLY GLY D . n 
C 1 80  HIS 80  80  80  HIS HIS D . n 
C 1 81  SER 81  81  81  SER SER D . n 
C 1 82  MET 82  82  82  MET MET D . n 
C 1 83  GLN 83  83  83  GLN GLN D . n 
C 1 84  ASN 84  84  84  ASN ASN D . n 
C 1 85  CYS 85  85  85  CYS CYS D . n 
C 1 86  VAL 86  86  86  VAL VAL D . n 
C 1 87  LEU 87  87  87  LEU LEU D . n 
C 1 88  LYS 88  88  88  LYS LYS D . n 
C 1 89  LEU 89  89  89  LEU LEU D . n 
C 1 90  LYS 90  90  90  LYS LYS D . n 
C 1 91  VAL 91  91  91  VAL VAL D . n 
C 1 92  ASP 92  92  92  ASP ASP D . n 
C 1 93  THR 93  93  93  THR THR D . n 
C 1 94  ALA 94  94  94  ALA ALA D . n 
C 1 95  ASN 95  95  95  ASN ASN D . n 
C 1 96  PRO 96  96  96  PRO PRO D . n 
C 1 97  LYS 97  97  97  LYS LYS D . n 
C 1 98  THR 98  98  98  THR THR D . n 
C 1 99  PRO 99  99  99  PRO PRO D . n 
C 1 100 LYS 100 100 100 LYS LYS D . n 
C 1 101 TYR 101 101 101 TYR TYR D . n 
C 1 102 LYS 102 102 102 LYS LYS D . n 
C 1 103 PHE 103 103 103 PHE PHE D . n 
C 1 104 VAL 104 104 104 VAL VAL D . n 
C 1 105 ARG 105 105 105 ARG ARG D . n 
C 1 106 ILE 106 106 106 ILE ILE D . n 
C 1 107 GLN 107 107 107 GLN GLN D . n 
C 1 108 PRO 108 108 108 PRO PRO D . n 
C 1 109 GLY 109 109 109 GLY GLY D . n 
C 1 110 GLN 110 110 110 GLN GLN D . n 
C 1 111 THR 111 111 111 THR THR D . n 
C 1 112 PHE 112 112 112 PHE PHE D . n 
C 1 113 SER 113 113 113 SER SER D . n 
C 1 114 VAL 114 114 114 VAL VAL D . n 
C 1 115 LEU 115 115 115 LEU LEU D . n 
C 1 116 ALA 116 116 116 ALA ALA D . n 
C 1 117 CYS 117 117 117 CYS CYS D . n 
C 1 118 TYR 118 118 118 TYR TYR D . n 
C 1 119 ASN 119 119 119 ASN ASN D . n 
C 1 120 GLY 120 120 120 GLY GLY D . n 
C 1 121 SER 121 121 121 SER SER D . n 
C 1 122 PRO 122 122 122 PRO PRO D . n 
C 1 123 SER 123 123 123 SER SER D . n 
C 1 124 GLY 124 124 124 GLY GLY D . n 
C 1 125 VAL 125 125 125 VAL VAL D . n 
C 1 126 TYR 126 126 126 TYR TYR D . n 
C 1 127 GLN 127 127 127 GLN GLN D . n 
C 1 128 CYS 128 128 128 CYS CYS D . n 
C 1 129 ALA 129 129 129 ALA ALA D . n 
C 1 130 MET 130 130 130 MET MET D . n 
C 1 131 ARG 131 131 131 ARG ARG D . n 
C 1 132 HIS 132 132 132 HIS HIS D . n 
C 1 133 ASN 133 133 133 ASN ASN D . n 
C 1 134 PHE 134 134 134 PHE PHE D . n 
C 1 135 THR 135 135 135 THR THR D . n 
C 1 136 ILE 136 136 136 ILE ILE D . n 
C 1 137 LYS 137 137 137 LYS LYS D . n 
C 1 138 GLY 138 138 138 GLY GLY D . n 
C 1 139 SER 139 139 139 SER SER D . n 
C 1 140 PHE 140 140 140 PHE PHE D . n 
C 1 141 LEU 141 141 141 LEU LEU D . n 
C 1 142 ASN 142 142 142 ASN ASN D . n 
C 1 143 GLY 143 143 143 GLY GLY D . n 
C 1 144 SER 144 144 144 SER SER D . n 
C 1 145 CYS 145 145 145 CYS CYS D . n 
C 1 146 GLY 146 146 146 GLY GLY D . n 
C 1 147 SER 147 147 147 SER SER D . n 
C 1 148 VAL 148 148 148 VAL VAL D . n 
C 1 149 GLY 149 149 149 GLY GLY D . n 
C 1 150 PHE 150 150 150 PHE PHE D . n 
C 1 151 ASN 151 151 151 ASN ASN D . n 
C 1 152 ILE 152 152 152 ILE ILE D . n 
C 1 153 ASP 153 153 153 ASP ASP D . n 
C 1 154 TYR 154 154 154 TYR TYR D . n 
C 1 155 ASP 155 155 155 ASP ASP D . n 
C 1 156 CYS 156 156 156 CYS CYS D . n 
C 1 157 VAL 157 157 157 VAL VAL D . n 
C 1 158 SER 158 158 158 SER SER D . n 
C 1 159 PHE 159 159 159 PHE PHE D . n 
C 1 160 CYS 160 160 160 CYS CYS D . n 
C 1 161 TYR 161 161 161 TYR TYR D . n 
C 1 162 MET 162 162 162 MET MET D . n 
C 1 163 HIS 163 163 163 HIS HIS D . n 
C 1 164 HIS 164 164 164 HIS HIS D . n 
C 1 165 MET 165 165 165 MET MET D . n 
C 1 166 GLU 166 166 166 GLU GLU D . n 
C 1 167 LEU 167 167 167 LEU LEU D . n 
C 1 168 PRO 168 168 168 PRO PRO D . n 
C 1 169 THR 169 169 169 THR THR D . n 
C 1 170 GLY 170 170 170 GLY GLY D . n 
C 1 171 VAL 171 171 171 VAL VAL D . n 
C 1 172 HIS 172 172 172 HIS HIS D . n 
C 1 173 ALA 173 173 173 ALA ALA D . n 
C 1 174 GLY 174 174 174 GLY GLY D . n 
C 1 175 THR 175 175 175 THR THR D . n 
C 1 176 ASP 176 176 176 ASP ASP D . n 
C 1 177 LEU 177 177 177 LEU LEU D . n 
C 1 178 GLU 178 178 178 GLU GLU D . n 
C 1 179 GLY 179 179 179 GLY GLY D . n 
C 1 180 ASN 180 180 180 ASN ASN D . n 
C 1 181 PHE 181 181 181 PHE PHE D . n 
C 1 182 TYR 182 182 182 TYR TYR D . n 
C 1 183 GLY 183 183 183 GLY GLY D . n 
C 1 184 PRO 184 184 184 PRO PRO D . n 
C 1 185 PHE 185 185 185 PHE PHE D . n 
C 1 186 VAL 186 186 186 VAL VAL D . n 
C 1 187 ASP 187 187 187 ASP ASP D . n 
C 1 188 ARG 188 188 188 ARG ARG D . n 
C 1 189 GLN 189 189 189 GLN GLN D . n 
C 1 190 THR 190 190 190 THR THR D . n 
C 1 191 ALA 191 191 191 ALA ALA D . n 
C 1 192 GLN 192 192 192 GLN GLN D . n 
C 1 193 ALA 193 193 193 ALA ALA D . n 
C 1 194 ALA 194 194 194 ALA ALA D . n 
C 1 195 GLY 195 195 195 GLY GLY D . n 
C 1 196 THR 196 196 196 THR THR D . n 
C 1 197 ASP 197 197 197 ASP ASP D . n 
C 1 198 THR 198 198 198 THR THR D . n 
C 1 199 THR 199 199 199 THR THR D . n 
C 1 200 ILE 200 200 200 ILE ILE D . n 
C 1 201 THR 201 201 201 THR THR D . n 
C 1 202 VAL 202 202 202 VAL VAL D . n 
C 1 203 ASN 203 203 203 ASN ASN D . n 
C 1 204 VAL 204 204 204 VAL VAL D . n 
C 1 205 LEU 205 205 205 LEU LEU D . n 
C 1 206 ALA 206 206 206 ALA ALA D . n 
C 1 207 TRP 207 207 207 TRP TRP D . n 
C 1 208 LEU 208 208 208 LEU LEU D . n 
C 1 209 TYR 209 209 209 TYR TYR D . n 
C 1 210 ALA 210 210 210 ALA ALA D . n 
C 1 211 ALA 211 211 211 ALA ALA D . n 
C 1 212 VAL 212 212 212 VAL VAL D . n 
C 1 213 ILE 213 213 213 ILE ILE D . n 
C 1 214 ASN 214 214 214 ASN ASN D . n 
C 1 215 GLY 215 215 215 GLY GLY D . n 
C 1 216 ASP 216 216 216 ASP ASP D . n 
C 1 217 ARG 217 217 217 ARG ARG D . n 
C 1 218 TRP 218 218 218 TRP TRP D . n 
C 1 219 PHE 219 219 219 PHE PHE D . n 
C 1 220 LEU 220 220 220 LEU LEU D . n 
C 1 221 ASN 221 221 221 ASN ASN D . n 
C 1 222 ARG 222 222 222 ARG ARG D . n 
C 1 223 PHE 223 223 223 PHE PHE D . n 
C 1 224 THR 224 224 224 THR THR D . n 
C 1 225 THR 225 225 225 THR THR D . n 
C 1 226 THR 226 226 226 THR THR D . n 
C 1 227 LEU 227 227 227 LEU LEU D . n 
C 1 228 ASN 228 228 228 ASN ASN D . n 
C 1 229 ASP 229 229 229 ASP ASP D . n 
C 1 230 PHE 230 230 230 PHE PHE D . n 
C 1 231 ASN 231 231 231 ASN ASN D . n 
C 1 232 LEU 232 232 232 LEU LEU D . n 
C 1 233 VAL 233 233 233 VAL VAL D . n 
C 1 234 ALA 234 234 234 ALA ALA D . n 
C 1 235 MET 235 235 235 MET MET D . n 
C 1 236 LYS 236 236 236 LYS LYS D . n 
C 1 237 TYR 237 237 237 TYR TYR D . n 
C 1 238 ASN 238 238 238 ASN ASN D . n 
C 1 239 TYR 239 239 239 TYR TYR D . n 
C 1 240 GLU 240 240 240 GLU GLU D . n 
C 1 241 PRO 241 241 241 PRO PRO D . n 
C 1 242 LEU 242 242 242 LEU LEU D . n 
C 1 243 THR 243 243 243 THR THR D . n 
C 1 244 GLN 244 244 244 GLN GLN D . n 
C 1 245 ASP 245 245 245 ASP ASP D . n 
C 1 246 HIS 246 246 246 HIS HIS D . n 
C 1 247 VAL 247 247 247 VAL VAL D . n 
C 1 248 ASP 248 248 248 ASP ASP D . n 
C 1 249 ILE 249 249 249 ILE ILE D . n 
C 1 250 LEU 250 250 250 LEU LEU D . n 
C 1 251 GLY 251 251 251 GLY GLY D . n 
C 1 252 PRO 252 252 252 PRO PRO D . n 
C 1 253 LEU 253 253 253 LEU LEU D . n 
C 1 254 SER 254 254 254 SER SER D . n 
C 1 255 ALA 255 255 255 ALA ALA D . n 
C 1 256 GLN 256 256 256 GLN GLN D . n 
C 1 257 THR 257 257 257 THR THR D . n 
C 1 258 GLY 258 258 258 GLY GLY D . n 
C 1 259 ILE 259 259 259 ILE ILE D . n 
C 1 260 ALA 260 260 260 ALA ALA D . n 
C 1 261 VAL 261 261 261 VAL VAL D . n 
C 1 262 LEU 262 262 262 LEU LEU D . n 
C 1 263 ASP 263 263 263 ASP ASP D . n 
C 1 264 MET 264 264 264 MET MET D . n 
C 1 265 CYS 265 265 265 CYS CYS D . n 
C 1 266 ALA 266 266 266 ALA ALA D . n 
C 1 267 SER 267 267 267 SER SER D . n 
C 1 268 LEU 268 268 268 LEU LEU D . n 
C 1 269 LYS 269 269 269 LYS LYS D . n 
C 1 270 GLU 270 270 270 GLU GLU D . n 
C 1 271 LEU 271 271 271 LEU LEU D . n 
C 1 272 LEU 272 272 272 LEU LEU D . n 
C 1 273 GLN 273 273 273 GLN GLN D . n 
C 1 274 ASN 274 274 274 ASN ASN D . n 
C 1 275 GLY 275 275 275 GLY GLY D . n 
C 1 276 MET 276 276 276 MET MET D . n 
C 1 277 ASN 277 277 277 ASN ASN D . n 
C 1 278 GLY 278 278 278 GLY GLY D . n 
C 1 279 ARG 279 279 279 ARG ARG D . n 
C 1 280 THR 280 280 280 THR THR D . n 
C 1 281 ILE 281 281 281 ILE ILE D . n 
C 1 282 LEU 282 282 282 LEU LEU D . n 
C 1 283 GLY 283 283 283 GLY GLY D . n 
C 1 284 SER 284 284 284 SER SER D . n 
C 1 285 ALA 285 285 285 ALA ALA D . n 
C 1 286 LEU 286 286 286 LEU LEU D . n 
C 1 287 LEU 287 287 287 LEU LEU D . n 
C 1 288 GLU 288 288 288 GLU GLU D . n 
C 1 289 ASP 289 289 289 ASP ASP D . n 
C 1 290 GLU 290 290 290 GLU GLU D . n 
C 1 291 PHE 291 291 291 PHE PHE D . n 
C 1 292 THR 292 292 292 THR THR D . n 
C 1 293 PRO 293 293 293 PRO PRO D . n 
C 1 294 PHE 294 294 294 PHE PHE D . n 
C 1 295 ASP 295 295 295 ASP ASP D . n 
C 1 296 VAL 296 296 296 VAL VAL D . n 
C 1 297 VAL 297 297 297 VAL VAL D . n 
C 1 298 ARG 298 298 298 ARG ARG D . n 
C 1 299 GLN 299 299 299 GLN GLN D . n 
C 1 300 CYS 300 300 300 CYS CYS D . n 
C 1 301 SER 301 301 301 SER SER D . n 
C 1 302 GLY 302 302 302 GLY GLY D . n 
C 1 303 VAL 303 303 303 VAL VAL D . n 
C 1 304 THR 304 304 304 THR THR D . n 
C 1 305 PHE 305 305 305 PHE PHE D . n 
C 1 306 GLN 306 306 ?   ?   ?   D . n 
D 1 1   SER 1   1   1   SER SER C . n 
D 1 2   GLY 2   2   2   GLY GLY C . n 
D 1 3   PHE 3   3   3   PHE PHE C . n 
D 1 4   ARG 4   4   4   ARG ARG C . n 
D 1 5   LYS 5   5   5   LYS LYS C . n 
D 1 6   MET 6   6   6   MET MET C . n 
D 1 7   ALA 7   7   7   ALA ALA C . n 
D 1 8   PHE 8   8   8   PHE PHE C . n 
D 1 9   PRO 9   9   9   PRO PRO C . n 
D 1 10  SER 10  10  10  SER SER C . n 
D 1 11  GLY 11  11  11  GLY GLY C . n 
D 1 12  LYS 12  12  12  LYS LYS C . n 
D 1 13  VAL 13  13  13  VAL VAL C . n 
D 1 14  GLU 14  14  14  GLU GLU C . n 
D 1 15  GLY 15  15  15  GLY GLY C . n 
D 1 16  CYS 16  16  16  CYS CYS C . n 
D 1 17  MET 17  17  17  MET MET C . n 
D 1 18  VAL 18  18  18  VAL VAL C . n 
D 1 19  GLN 19  19  19  GLN GLN C . n 
D 1 20  VAL 20  20  20  VAL VAL C . n 
D 1 21  THR 21  21  21  THR THR C . n 
D 1 22  CYS 22  22  22  CYS CYS C . n 
D 1 23  GLY 23  23  23  GLY GLY C . n 
D 1 24  THR 24  24  24  THR THR C . n 
D 1 25  THR 25  25  25  THR THR C . n 
D 1 26  THR 26  26  26  THR THR C . n 
D 1 27  LEU 27  27  27  LEU LEU C . n 
D 1 28  ASN 28  28  28  ASN ASN C . n 
D 1 29  GLY 29  29  29  GLY GLY C . n 
D 1 30  LEU 30  30  30  LEU LEU C . n 
D 1 31  TRP 31  31  31  TRP TRP C . n 
D 1 32  LEU 32  32  32  LEU LEU C . n 
D 1 33  ASP 33  33  33  ASP ASP C . n 
D 1 34  ASP 34  34  34  ASP ASP C . n 
D 1 35  VAL 35  35  35  VAL VAL C . n 
D 1 36  VAL 36  36  36  VAL VAL C . n 
D 1 37  TYR 37  37  37  TYR TYR C . n 
D 1 38  CYS 38  38  38  CYS CYS C . n 
D 1 39  PRO 39  39  39  PRO PRO C . n 
D 1 40  ARG 40  40  40  ARG ARG C . n 
D 1 41  HIS 41  41  41  HIS HIS C . n 
D 1 42  VAL 42  42  42  VAL VAL C . n 
D 1 43  ILE 43  43  43  ILE ILE C . n 
D 1 44  CYS 44  44  44  CYS CYS C . n 
D 1 45  THR 45  45  45  THR THR C . n 
D 1 46  SER 46  46  46  SER SER C . n 
D 1 47  GLU 47  47  47  GLU GLU C . n 
D 1 48  ASP 48  48  48  ASP ASP C . n 
D 1 49  MET 49  49  49  MET MET C . n 
D 1 50  LEU 50  50  50  LEU LEU C . n 
D 1 51  ASN 51  51  51  ASN ASN C . n 
D 1 52  PRO 52  52  52  PRO PRO C . n 
D 1 53  ASN 53  53  53  ASN ASN C . n 
D 1 54  TYR 54  54  54  TYR TYR C . n 
D 1 55  GLU 55  55  55  GLU GLU C . n 
D 1 56  ASP 56  56  56  ASP ASP C . n 
D 1 57  LEU 57  57  57  LEU LEU C . n 
D 1 58  LEU 58  58  58  LEU LEU C . n 
D 1 59  ILE 59  59  59  ILE ILE C . n 
D 1 60  ARG 60  60  60  ARG ARG C . n 
D 1 61  LYS 61  61  61  LYS LYS C . n 
D 1 62  SER 62  62  62  SER SER C . n 
D 1 63  ASN 63  63  63  ASN ASN C . n 
D 1 64  HIS 64  64  64  HIS HIS C . n 
D 1 65  ASN 65  65  65  ASN ASN C . n 
D 1 66  PHE 66  66  66  PHE PHE C . n 
D 1 67  LEU 67  67  67  LEU LEU C . n 
D 1 68  VAL 68  68  68  VAL VAL C . n 
D 1 69  GLN 69  69  69  GLN GLN C . n 
D 1 70  ALA 70  70  70  ALA ALA C . n 
D 1 71  GLY 71  71  71  GLY GLY C . n 
D 1 72  ASN 72  72  72  ASN ASN C . n 
D 1 73  VAL 73  73  73  VAL VAL C . n 
D 1 74  GLN 74  74  74  GLN GLN C . n 
D 1 75  LEU 75  75  75  LEU LEU C . n 
D 1 76  ARG 76  76  76  ARG ARG C . n 
D 1 77  VAL 77  77  77  VAL VAL C . n 
D 1 78  ILE 78  78  78  ILE ILE C . n 
D 1 79  GLY 79  79  79  GLY GLY C . n 
D 1 80  HIS 80  80  80  HIS HIS C . n 
D 1 81  SER 81  81  81  SER SER C . n 
D 1 82  MET 82  82  82  MET MET C . n 
D 1 83  GLN 83  83  83  GLN GLN C . n 
D 1 84  ASN 84  84  84  ASN ASN C . n 
D 1 85  CYS 85  85  85  CYS CYS C . n 
D 1 86  VAL 86  86  86  VAL VAL C . n 
D 1 87  LEU 87  87  87  LEU LEU C . n 
D 1 88  LYS 88  88  88  LYS LYS C . n 
D 1 89  LEU 89  89  89  LEU LEU C . n 
D 1 90  LYS 90  90  90  LYS LYS C . n 
D 1 91  VAL 91  91  91  VAL VAL C . n 
D 1 92  ASP 92  92  92  ASP ASP C . n 
D 1 93  THR 93  93  93  THR THR C . n 
D 1 94  ALA 94  94  94  ALA ALA C . n 
D 1 95  ASN 95  95  95  ASN ASN C . n 
D 1 96  PRO 96  96  96  PRO PRO C . n 
D 1 97  LYS 97  97  97  LYS LYS C . n 
D 1 98  THR 98  98  98  THR THR C . n 
D 1 99  PRO 99  99  99  PRO PRO C . n 
D 1 100 LYS 100 100 100 LYS LYS C . n 
D 1 101 TYR 101 101 101 TYR TYR C . n 
D 1 102 LYS 102 102 102 LYS LYS C . n 
D 1 103 PHE 103 103 103 PHE PHE C . n 
D 1 104 VAL 104 104 104 VAL VAL C . n 
D 1 105 ARG 105 105 105 ARG ARG C . n 
D 1 106 ILE 106 106 106 ILE ILE C . n 
D 1 107 GLN 107 107 107 GLN GLN C . n 
D 1 108 PRO 108 108 108 PRO PRO C . n 
D 1 109 GLY 109 109 109 GLY GLY C . n 
D 1 110 GLN 110 110 110 GLN GLN C . n 
D 1 111 THR 111 111 111 THR THR C . n 
D 1 112 PHE 112 112 112 PHE PHE C . n 
D 1 113 SER 113 113 113 SER SER C . n 
D 1 114 VAL 114 114 114 VAL VAL C . n 
D 1 115 LEU 115 115 115 LEU LEU C . n 
D 1 116 ALA 116 116 116 ALA ALA C . n 
D 1 117 CYS 117 117 117 CYS CYS C . n 
D 1 118 TYR 118 118 118 TYR TYR C . n 
D 1 119 ASN 119 119 119 ASN ASN C . n 
D 1 120 GLY 120 120 120 GLY GLY C . n 
D 1 121 SER 121 121 121 SER SER C . n 
D 1 122 PRO 122 122 122 PRO PRO C . n 
D 1 123 SER 123 123 123 SER SER C . n 
D 1 124 GLY 124 124 124 GLY GLY C . n 
D 1 125 VAL 125 125 125 VAL VAL C . n 
D 1 126 TYR 126 126 126 TYR TYR C . n 
D 1 127 GLN 127 127 127 GLN GLN C . n 
D 1 128 CYS 128 128 128 CYS CYS C . n 
D 1 129 ALA 129 129 129 ALA ALA C . n 
D 1 130 MET 130 130 130 MET MET C . n 
D 1 131 ARG 131 131 131 ARG ARG C . n 
D 1 132 HIS 132 132 132 HIS HIS C . n 
D 1 133 ASN 133 133 133 ASN ASN C . n 
D 1 134 PHE 134 134 134 PHE PHE C . n 
D 1 135 THR 135 135 135 THR THR C . n 
D 1 136 ILE 136 136 136 ILE ILE C . n 
D 1 137 LYS 137 137 137 LYS LYS C . n 
D 1 138 GLY 138 138 138 GLY GLY C . n 
D 1 139 SER 139 139 139 SER SER C . n 
D 1 140 PHE 140 140 140 PHE PHE C . n 
D 1 141 LEU 141 141 141 LEU LEU C . n 
D 1 142 ASN 142 142 142 ASN ASN C . n 
D 1 143 GLY 143 143 143 GLY GLY C . n 
D 1 144 SER 144 144 144 SER SER C . n 
D 1 145 CYS 145 145 145 CYS CYS C . n 
D 1 146 GLY 146 146 146 GLY GLY C . n 
D 1 147 SER 147 147 147 SER SER C . n 
D 1 148 VAL 148 148 148 VAL VAL C . n 
D 1 149 GLY 149 149 149 GLY GLY C . n 
D 1 150 PHE 150 150 150 PHE PHE C . n 
D 1 151 ASN 151 151 151 ASN ASN C . n 
D 1 152 ILE 152 152 152 ILE ILE C . n 
D 1 153 ASP 153 153 153 ASP ASP C . n 
D 1 154 TYR 154 154 154 TYR TYR C . n 
D 1 155 ASP 155 155 155 ASP ASP C . n 
D 1 156 CYS 156 156 156 CYS CYS C . n 
D 1 157 VAL 157 157 157 VAL VAL C . n 
D 1 158 SER 158 158 158 SER SER C . n 
D 1 159 PHE 159 159 159 PHE PHE C . n 
D 1 160 CYS 160 160 160 CYS CYS C . n 
D 1 161 TYR 161 161 161 TYR TYR C . n 
D 1 162 MET 162 162 162 MET MET C . n 
D 1 163 HIS 163 163 163 HIS HIS C . n 
D 1 164 HIS 164 164 164 HIS HIS C . n 
D 1 165 MET 165 165 165 MET MET C . n 
D 1 166 GLU 166 166 166 GLU GLU C . n 
D 1 167 LEU 167 167 167 LEU LEU C . n 
D 1 168 PRO 168 168 168 PRO PRO C . n 
D 1 169 THR 169 169 169 THR THR C . n 
D 1 170 GLY 170 170 170 GLY GLY C . n 
D 1 171 VAL 171 171 171 VAL VAL C . n 
D 1 172 HIS 172 172 172 HIS HIS C . n 
D 1 173 ALA 173 173 173 ALA ALA C . n 
D 1 174 GLY 174 174 174 GLY GLY C . n 
D 1 175 THR 175 175 175 THR THR C . n 
D 1 176 ASP 176 176 176 ASP ASP C . n 
D 1 177 LEU 177 177 177 LEU LEU C . n 
D 1 178 GLU 178 178 178 GLU GLU C . n 
D 1 179 GLY 179 179 179 GLY GLY C . n 
D 1 180 ASN 180 180 180 ASN ASN C . n 
D 1 181 PHE 181 181 181 PHE PHE C . n 
D 1 182 TYR 182 182 182 TYR TYR C . n 
D 1 183 GLY 183 183 183 GLY GLY C . n 
D 1 184 PRO 184 184 184 PRO PRO C . n 
D 1 185 PHE 185 185 185 PHE PHE C . n 
D 1 186 VAL 186 186 186 VAL VAL C . n 
D 1 187 ASP 187 187 187 ASP ASP C . n 
D 1 188 ARG 188 188 188 ARG ARG C . n 
D 1 189 GLN 189 189 189 GLN GLN C . n 
D 1 190 THR 190 190 190 THR THR C . n 
D 1 191 ALA 191 191 191 ALA ALA C . n 
D 1 192 GLN 192 192 192 GLN GLN C . n 
D 1 193 ALA 193 193 193 ALA ALA C . n 
D 1 194 ALA 194 194 194 ALA ALA C . n 
D 1 195 GLY 195 195 195 GLY GLY C . n 
D 1 196 THR 196 196 196 THR THR C . n 
D 1 197 ASP 197 197 197 ASP ASP C . n 
D 1 198 THR 198 198 198 THR THR C . n 
D 1 199 THR 199 199 199 THR THR C . n 
D 1 200 ILE 200 200 200 ILE ILE C . n 
D 1 201 THR 201 201 201 THR THR C . n 
D 1 202 VAL 202 202 202 VAL VAL C . n 
D 1 203 ASN 203 203 203 ASN ASN C . n 
D 1 204 VAL 204 204 204 VAL VAL C . n 
D 1 205 LEU 205 205 205 LEU LEU C . n 
D 1 206 ALA 206 206 206 ALA ALA C . n 
D 1 207 TRP 207 207 207 TRP TRP C . n 
D 1 208 LEU 208 208 208 LEU LEU C . n 
D 1 209 TYR 209 209 209 TYR TYR C . n 
D 1 210 ALA 210 210 210 ALA ALA C . n 
D 1 211 ALA 211 211 211 ALA ALA C . n 
D 1 212 VAL 212 212 212 VAL VAL C . n 
D 1 213 ILE 213 213 213 ILE ILE C . n 
D 1 214 ASN 214 214 214 ASN ASN C . n 
D 1 215 GLY 215 215 215 GLY GLY C . n 
D 1 216 ASP 216 216 216 ASP ASP C . n 
D 1 217 ARG 217 217 217 ARG ARG C . n 
D 1 218 TRP 218 218 218 TRP TRP C . n 
D 1 219 PHE 219 219 219 PHE PHE C . n 
D 1 220 LEU 220 220 220 LEU LEU C . n 
D 1 221 ASN 221 221 221 ASN ASN C . n 
D 1 222 ARG 222 222 222 ARG ARG C . n 
D 1 223 PHE 223 223 223 PHE PHE C . n 
D 1 224 THR 224 224 224 THR THR C . n 
D 1 225 THR 225 225 225 THR THR C . n 
D 1 226 THR 226 226 226 THR THR C . n 
D 1 227 LEU 227 227 227 LEU LEU C . n 
D 1 228 ASN 228 228 228 ASN ASN C . n 
D 1 229 ASP 229 229 229 ASP ASP C . n 
D 1 230 PHE 230 230 230 PHE PHE C . n 
D 1 231 ASN 231 231 231 ASN ASN C . n 
D 1 232 LEU 232 232 232 LEU LEU C . n 
D 1 233 VAL 233 233 233 VAL VAL C . n 
D 1 234 ALA 234 234 234 ALA ALA C . n 
D 1 235 MET 235 235 235 MET MET C . n 
D 1 236 LYS 236 236 236 LYS LYS C . n 
D 1 237 TYR 237 237 237 TYR TYR C . n 
D 1 238 ASN 238 238 238 ASN ASN C . n 
D 1 239 TYR 239 239 239 TYR TYR C . n 
D 1 240 GLU 240 240 240 GLU GLU C . n 
D 1 241 PRO 241 241 241 PRO PRO C . n 
D 1 242 LEU 242 242 242 LEU LEU C . n 
D 1 243 THR 243 243 243 THR THR C . n 
D 1 244 GLN 244 244 244 GLN GLN C . n 
D 1 245 ASP 245 245 245 ASP ASP C . n 
D 1 246 HIS 246 246 246 HIS HIS C . n 
D 1 247 VAL 247 247 247 VAL VAL C . n 
D 1 248 ASP 248 248 248 ASP ASP C . n 
D 1 249 ILE 249 249 249 ILE ILE C . n 
D 1 250 LEU 250 250 250 LEU LEU C . n 
D 1 251 GLY 251 251 251 GLY GLY C . n 
D 1 252 PRO 252 252 252 PRO PRO C . n 
D 1 253 LEU 253 253 253 LEU LEU C . n 
D 1 254 SER 254 254 254 SER SER C . n 
D 1 255 ALA 255 255 255 ALA ALA C . n 
D 1 256 GLN 256 256 256 GLN GLN C . n 
D 1 257 THR 257 257 257 THR THR C . n 
D 1 258 GLY 258 258 258 GLY GLY C . n 
D 1 259 ILE 259 259 259 ILE ILE C . n 
D 1 260 ALA 260 260 260 ALA ALA C . n 
D 1 261 VAL 261 261 261 VAL VAL C . n 
D 1 262 LEU 262 262 262 LEU LEU C . n 
D 1 263 ASP 263 263 263 ASP ASP C . n 
D 1 264 MET 264 264 264 MET MET C . n 
D 1 265 CYS 265 265 265 CYS CYS C . n 
D 1 266 ALA 266 266 266 ALA ALA C . n 
D 1 267 SER 267 267 267 SER SER C . n 
D 1 268 LEU 268 268 268 LEU LEU C . n 
D 1 269 LYS 269 269 269 LYS LYS C . n 
D 1 270 GLU 270 270 270 GLU GLU C . n 
D 1 271 LEU 271 271 271 LEU LEU C . n 
D 1 272 LEU 272 272 272 LEU LEU C . n 
D 1 273 GLN 273 273 273 GLN GLN C . n 
D 1 274 ASN 274 274 274 ASN ASN C . n 
D 1 275 GLY 275 275 275 GLY GLY C . n 
D 1 276 MET 276 276 276 MET MET C . n 
D 1 277 ASN 277 277 277 ASN ASN C . n 
D 1 278 GLY 278 278 278 GLY GLY C . n 
D 1 279 ARG 279 279 279 ARG ARG C . n 
D 1 280 THR 280 280 280 THR THR C . n 
D 1 281 ILE 281 281 281 ILE ILE C . n 
D 1 282 LEU 282 282 282 LEU LEU C . n 
D 1 283 GLY 283 283 283 GLY GLY C . n 
D 1 284 SER 284 284 284 SER SER C . n 
D 1 285 ALA 285 285 285 ALA ALA C . n 
D 1 286 LEU 286 286 286 LEU LEU C . n 
D 1 287 LEU 287 287 287 LEU LEU C . n 
D 1 288 GLU 288 288 288 GLU GLU C . n 
D 1 289 ASP 289 289 289 ASP ASP C . n 
D 1 290 GLU 290 290 290 GLU GLU C . n 
D 1 291 PHE 291 291 291 PHE PHE C . n 
D 1 292 THR 292 292 292 THR THR C . n 
D 1 293 PRO 293 293 293 PRO PRO C . n 
D 1 294 PHE 294 294 294 PHE PHE C . n 
D 1 295 ASP 295 295 295 ASP ASP C . n 
D 1 296 VAL 296 296 296 VAL VAL C . n 
D 1 297 VAL 297 297 297 VAL VAL C . n 
D 1 298 ARG 298 298 298 ARG ARG C . n 
D 1 299 GLN 299 299 299 GLN GLN C . n 
D 1 300 CYS 300 300 300 CYS CYS C . n 
D 1 301 SER 301 301 301 SER SER C . n 
D 1 302 GLY 302 302 302 GLY GLY C . n 
D 1 303 VAL 303 303 303 VAL VAL C . n 
D 1 304 THR 304 304 304 THR THR C . n 
D 1 305 PHE 305 305 305 PHE PHE C . n 
D 1 306 GLN 306 306 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        O6K 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   O6K 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 O6K 1   401 402 O6K O6K A . 
F 3 CL  1   402 2   CL  CL  A . 
G 2 O6K 1   401 401 O6K O6K B . 
H 2 O6K 1   401 402 O6K O6K D . 
I 3 CL  1   402 3   CL  CL  D . 
J 2 O6K 1   401 401 O6K O6K C . 
K 3 CL  1   402 1   CL  CL  C . 
L 4 HOH 1   501 342 HOH HOH A . 
L 4 HOH 2   502 243 HOH HOH A . 
L 4 HOH 3   503 271 HOH HOH A . 
L 4 HOH 4   504 233 HOH HOH A . 
L 4 HOH 5   505 301 HOH HOH A . 
L 4 HOH 6   506 338 HOH HOH A . 
L 4 HOH 7   507 269 HOH HOH A . 
L 4 HOH 8   508 270 HOH HOH A . 
L 4 HOH 9   509 229 HOH HOH A . 
L 4 HOH 10  510 336 HOH HOH A . 
L 4 HOH 11  511 248 HOH HOH A . 
L 4 HOH 12  512 41  HOH HOH A . 
L 4 HOH 13  513 145 HOH HOH A . 
L 4 HOH 14  514 21  HOH HOH A . 
L 4 HOH 15  515 209 HOH HOH A . 
L 4 HOH 16  516 194 HOH HOH A . 
L 4 HOH 17  517 17  HOH HOH A . 
L 4 HOH 18  518 239 HOH HOH A . 
L 4 HOH 19  519 114 HOH HOH A . 
L 4 HOH 20  520 153 HOH HOH A . 
L 4 HOH 21  521 242 HOH HOH A . 
L 4 HOH 22  522 321 HOH HOH A . 
L 4 HOH 23  523 250 HOH HOH A . 
L 4 HOH 24  524 65  HOH HOH A . 
L 4 HOH 25  525 107 HOH HOH A . 
L 4 HOH 26  526 93  HOH HOH A . 
L 4 HOH 27  527 6   HOH HOH A . 
L 4 HOH 28  528 331 HOH HOH A . 
L 4 HOH 29  529 85  HOH HOH A . 
L 4 HOH 30  530 68  HOH HOH A . 
L 4 HOH 31  531 56  HOH HOH A . 
L 4 HOH 32  532 111 HOH HOH A . 
L 4 HOH 33  533 244 HOH HOH A . 
L 4 HOH 34  534 149 HOH HOH A . 
L 4 HOH 35  535 134 HOH HOH A . 
L 4 HOH 36  536 185 HOH HOH A . 
L 4 HOH 37  537 15  HOH HOH A . 
L 4 HOH 38  538 255 HOH HOH A . 
L 4 HOH 39  539 353 HOH HOH A . 
L 4 HOH 40  540 47  HOH HOH A . 
L 4 HOH 41  541 124 HOH HOH A . 
L 4 HOH 42  542 155 HOH HOH A . 
L 4 HOH 43  543 292 HOH HOH A . 
L 4 HOH 44  544 189 HOH HOH A . 
L 4 HOH 45  545 322 HOH HOH A . 
L 4 HOH 46  546 46  HOH HOH A . 
L 4 HOH 47  547 182 HOH HOH A . 
L 4 HOH 48  548 307 HOH HOH A . 
L 4 HOH 49  549 278 HOH HOH A . 
L 4 HOH 50  550 96  HOH HOH A . 
L 4 HOH 51  551 112 HOH HOH A . 
L 4 HOH 52  552 196 HOH HOH A . 
L 4 HOH 53  553 201 HOH HOH A . 
L 4 HOH 54  554 123 HOH HOH A . 
L 4 HOH 55  555 290 HOH HOH A . 
L 4 HOH 56  556 295 HOH HOH A . 
L 4 HOH 57  557 36  HOH HOH A . 
L 4 HOH 58  558 88  HOH HOH A . 
L 4 HOH 59  559 174 HOH HOH A . 
L 4 HOH 60  560 81  HOH HOH A . 
L 4 HOH 61  561 4   HOH HOH A . 
L 4 HOH 62  562 148 HOH HOH A . 
L 4 HOH 63  563 1   HOH HOH A . 
L 4 HOH 64  564 99  HOH HOH A . 
L 4 HOH 65  565 197 HOH HOH A . 
L 4 HOH 66  566 71  HOH HOH A . 
L 4 HOH 67  567 212 HOH HOH A . 
L 4 HOH 68  568 53  HOH HOH A . 
L 4 HOH 69  569 252 HOH HOH A . 
L 4 HOH 70  570 39  HOH HOH A . 
L 4 HOH 71  571 340 HOH HOH A . 
L 4 HOH 72  572 9   HOH HOH A . 
L 4 HOH 73  573 216 HOH HOH A . 
L 4 HOH 74  574 167 HOH HOH A . 
L 4 HOH 75  575 205 HOH HOH A . 
L 4 HOH 76  576 94  HOH HOH A . 
L 4 HOH 77  577 186 HOH HOH A . 
L 4 HOH 78  578 241 HOH HOH A . 
L 4 HOH 79  579 253 HOH HOH A . 
L 4 HOH 80  580 116 HOH HOH A . 
L 4 HOH 81  581 144 HOH HOH A . 
L 4 HOH 82  582 230 HOH HOH A . 
L 4 HOH 83  583 328 HOH HOH A . 
L 4 HOH 84  584 191 HOH HOH A . 
L 4 HOH 85  585 138 HOH HOH A . 
L 4 HOH 86  586 135 HOH HOH A . 
L 4 HOH 87  587 161 HOH HOH A . 
L 4 HOH 88  588 227 HOH HOH A . 
L 4 HOH 89  589 273 HOH HOH A . 
L 4 HOH 90  590 359 HOH HOH A . 
L 4 HOH 91  591 163 HOH HOH A . 
L 4 HOH 92  592 62  HOH HOH A . 
L 4 HOH 93  593 343 HOH HOH A . 
L 4 HOH 94  594 348 HOH HOH A . 
L 4 HOH 95  595 329 HOH HOH A . 
L 4 HOH 96  596 245 HOH HOH A . 
L 4 HOH 97  597 176 HOH HOH A . 
L 4 HOH 98  598 183 HOH HOH A . 
L 4 HOH 99  599 192 HOH HOH A . 
L 4 HOH 100 600 352 HOH HOH A . 
L 4 HOH 101 601 291 HOH HOH A . 
L 4 HOH 102 602 95  HOH HOH A . 
L 4 HOH 103 603 276 HOH HOH A . 
L 4 HOH 104 604 311 HOH HOH A . 
M 4 HOH 1   501 281 HOH HOH B . 
M 4 HOH 2   502 265 HOH HOH B . 
M 4 HOH 3   503 264 HOH HOH B . 
M 4 HOH 4   504 261 HOH HOH B . 
M 4 HOH 5   505 288 HOH HOH B . 
M 4 HOH 6   506 240 HOH HOH B . 
M 4 HOH 7   507 284 HOH HOH B . 
M 4 HOH 8   508 254 HOH HOH B . 
M 4 HOH 9   509 349 HOH HOH B . 
M 4 HOH 10  510 298 HOH HOH B . 
M 4 HOH 11  511 235 HOH HOH B . 
M 4 HOH 12  512 195 HOH HOH B . 
M 4 HOH 13  513 42  HOH HOH B . 
M 4 HOH 14  514 102 HOH HOH B . 
M 4 HOH 15  515 150 HOH HOH B . 
M 4 HOH 16  516 34  HOH HOH B . 
M 4 HOH 17  517 104 HOH HOH B . 
M 4 HOH 18  518 126 HOH HOH B . 
M 4 HOH 19  519 108 HOH HOH B . 
M 4 HOH 20  520 158 HOH HOH B . 
M 4 HOH 21  521 79  HOH HOH B . 
M 4 HOH 22  522 103 HOH HOH B . 
M 4 HOH 23  523 139 HOH HOH B . 
M 4 HOH 24  524 159 HOH HOH B . 
M 4 HOH 25  525 234 HOH HOH B . 
M 4 HOH 26  526 180 HOH HOH B . 
M 4 HOH 27  527 156 HOH HOH B . 
M 4 HOH 28  528 315 HOH HOH B . 
M 4 HOH 29  529 55  HOH HOH B . 
M 4 HOH 30  530 217 HOH HOH B . 
M 4 HOH 31  531 64  HOH HOH B . 
M 4 HOH 32  532 75  HOH HOH B . 
M 4 HOH 33  533 18  HOH HOH B . 
M 4 HOH 34  534 10  HOH HOH B . 
M 4 HOH 35  535 105 HOH HOH B . 
M 4 HOH 36  536 59  HOH HOH B . 
M 4 HOH 37  537 190 HOH HOH B . 
M 4 HOH 38  538 171 HOH HOH B . 
M 4 HOH 39  539 129 HOH HOH B . 
M 4 HOH 40  540 57  HOH HOH B . 
M 4 HOH 41  541 187 HOH HOH B . 
M 4 HOH 42  542 101 HOH HOH B . 
M 4 HOH 43  543 35  HOH HOH B . 
M 4 HOH 44  544 303 HOH HOH B . 
M 4 HOH 45  545 325 HOH HOH B . 
M 4 HOH 46  546 172 HOH HOH B . 
M 4 HOH 47  547 40  HOH HOH B . 
M 4 HOH 48  548 256 HOH HOH B . 
M 4 HOH 49  549 146 HOH HOH B . 
M 4 HOH 50  550 296 HOH HOH B . 
M 4 HOH 51  551 122 HOH HOH B . 
M 4 HOH 52  552 175 HOH HOH B . 
M 4 HOH 53  553 203 HOH HOH B . 
M 4 HOH 54  554 37  HOH HOH B . 
M 4 HOH 55  555 12  HOH HOH B . 
M 4 HOH 56  556 23  HOH HOH B . 
M 4 HOH 57  557 11  HOH HOH B . 
M 4 HOH 58  558 266 HOH HOH B . 
M 4 HOH 59  559 160 HOH HOH B . 
M 4 HOH 60  560 32  HOH HOH B . 
M 4 HOH 61  561 27  HOH HOH B . 
M 4 HOH 62  562 136 HOH HOH B . 
M 4 HOH 63  563 238 HOH HOH B . 
M 4 HOH 64  564 16  HOH HOH B . 
M 4 HOH 65  565 25  HOH HOH B . 
M 4 HOH 66  566 299 HOH HOH B . 
M 4 HOH 67  567 106 HOH HOH B . 
M 4 HOH 68  568 87  HOH HOH B . 
M 4 HOH 69  569 312 HOH HOH B . 
M 4 HOH 70  570 282 HOH HOH B . 
M 4 HOH 71  571 128 HOH HOH B . 
M 4 HOH 72  572 74  HOH HOH B . 
M 4 HOH 73  573 117 HOH HOH B . 
M 4 HOH 74  574 20  HOH HOH B . 
M 4 HOH 75  575 345 HOH HOH B . 
M 4 HOH 76  576 356 HOH HOH B . 
M 4 HOH 77  577 305 HOH HOH B . 
M 4 HOH 78  578 33  HOH HOH B . 
M 4 HOH 79  579 294 HOH HOH B . 
M 4 HOH 80  580 61  HOH HOH B . 
M 4 HOH 81  581 309 HOH HOH B . 
M 4 HOH 82  582 198 HOH HOH B . 
M 4 HOH 83  583 358 HOH HOH B . 
M 4 HOH 84  584 210 HOH HOH B . 
M 4 HOH 85  585 357 HOH HOH B . 
M 4 HOH 86  586 222 HOH HOH B . 
M 4 HOH 87  587 354 HOH HOH B . 
M 4 HOH 88  588 287 HOH HOH B . 
M 4 HOH 89  589 225 HOH HOH B . 
M 4 HOH 90  590 320 HOH HOH B . 
M 4 HOH 91  591 90  HOH HOH B . 
M 4 HOH 92  592 211 HOH HOH B . 
M 4 HOH 93  593 360 HOH HOH B . 
N 4 HOH 1   501 351 HOH HOH D . 
N 4 HOH 2   502 272 HOH HOH D . 
N 4 HOH 3   503 263 HOH HOH D . 
N 4 HOH 4   504 78  HOH HOH D . 
N 4 HOH 5   505 286 HOH HOH D . 
N 4 HOH 6   506 236 HOH HOH D . 
N 4 HOH 7   507 355 HOH HOH D . 
N 4 HOH 8   508 208 HOH HOH D . 
N 4 HOH 9   509 302 HOH HOH D . 
N 4 HOH 10  510 308 HOH HOH D . 
N 4 HOH 11  511 109 HOH HOH D . 
N 4 HOH 12  512 199 HOH HOH D . 
N 4 HOH 13  513 26  HOH HOH D . 
N 4 HOH 14  514 3   HOH HOH D . 
N 4 HOH 15  515 8   HOH HOH D . 
N 4 HOH 16  516 127 HOH HOH D . 
N 4 HOH 17  517 324 HOH HOH D . 
N 4 HOH 18  518 179 HOH HOH D . 
N 4 HOH 19  519 19  HOH HOH D . 
N 4 HOH 20  520 121 HOH HOH D . 
N 4 HOH 21  521 279 HOH HOH D . 
N 4 HOH 22  522 262 HOH HOH D . 
N 4 HOH 23  523 67  HOH HOH D . 
N 4 HOH 24  524 339 HOH HOH D . 
N 4 HOH 25  525 72  HOH HOH D . 
N 4 HOH 26  526 60  HOH HOH D . 
N 4 HOH 27  527 38  HOH HOH D . 
N 4 HOH 28  528 130 HOH HOH D . 
N 4 HOH 29  529 214 HOH HOH D . 
N 4 HOH 30  530 58  HOH HOH D . 
N 4 HOH 31  531 193 HOH HOH D . 
N 4 HOH 32  532 346 HOH HOH D . 
N 4 HOH 33  533 178 HOH HOH D . 
N 4 HOH 34  534 91  HOH HOH D . 
N 4 HOH 35  535 337 HOH HOH D . 
N 4 HOH 36  536 125 HOH HOH D . 
N 4 HOH 37  537 184 HOH HOH D . 
N 4 HOH 38  538 251 HOH HOH D . 
N 4 HOH 39  539 28  HOH HOH D . 
N 4 HOH 40  540 89  HOH HOH D . 
N 4 HOH 41  541 86  HOH HOH D . 
N 4 HOH 42  542 231 HOH HOH D . 
N 4 HOH 43  543 98  HOH HOH D . 
N 4 HOH 44  544 277 HOH HOH D . 
N 4 HOH 45  545 215 HOH HOH D . 
N 4 HOH 46  546 100 HOH HOH D . 
N 4 HOH 47  547 49  HOH HOH D . 
N 4 HOH 48  548 77  HOH HOH D . 
N 4 HOH 49  549 341 HOH HOH D . 
N 4 HOH 50  550 220 HOH HOH D . 
N 4 HOH 51  551 147 HOH HOH D . 
N 4 HOH 52  552 285 HOH HOH D . 
N 4 HOH 53  553 228 HOH HOH D . 
N 4 HOH 54  554 54  HOH HOH D . 
N 4 HOH 55  555 51  HOH HOH D . 
N 4 HOH 56  556 113 HOH HOH D . 
N 4 HOH 57  557 213 HOH HOH D . 
N 4 HOH 58  558 362 HOH HOH D . 
N 4 HOH 59  559 133 HOH HOH D . 
N 4 HOH 60  560 141 HOH HOH D . 
N 4 HOH 61  561 283 HOH HOH D . 
N 4 HOH 62  562 164 HOH HOH D . 
N 4 HOH 63  563 83  HOH HOH D . 
N 4 HOH 64  564 70  HOH HOH D . 
N 4 HOH 65  565 119 HOH HOH D . 
N 4 HOH 66  566 313 HOH HOH D . 
N 4 HOH 67  567 110 HOH HOH D . 
N 4 HOH 68  568 257 HOH HOH D . 
N 4 HOH 69  569 204 HOH HOH D . 
N 4 HOH 70  570 327 HOH HOH D . 
N 4 HOH 71  571 365 HOH HOH D . 
N 4 HOH 72  572 333 HOH HOH D . 
N 4 HOH 73  573 247 HOH HOH D . 
N 4 HOH 74  574 45  HOH HOH D . 
N 4 HOH 75  575 304 HOH HOH D . 
N 4 HOH 76  576 162 HOH HOH D . 
N 4 HOH 77  577 249 HOH HOH D . 
N 4 HOH 78  578 300 HOH HOH D . 
N 4 HOH 79  579 306 HOH HOH D . 
N 4 HOH 80  580 363 HOH HOH D . 
N 4 HOH 81  581 140 HOH HOH D . 
N 4 HOH 82  582 143 HOH HOH D . 
N 4 HOH 83  583 335 HOH HOH D . 
N 4 HOH 84  584 151 HOH HOH D . 
N 4 HOH 85  585 316 HOH HOH D . 
N 4 HOH 86  586 221 HOH HOH D . 
N 4 HOH 87  587 280 HOH HOH D . 
N 4 HOH 88  588 168 HOH HOH D . 
N 4 HOH 89  589 334 HOH HOH D . 
O 4 HOH 1   501 310 HOH HOH C . 
O 4 HOH 2   502 267 HOH HOH C . 
O 4 HOH 3   503 293 HOH HOH C . 
O 4 HOH 4   504 258 HOH HOH C . 
O 4 HOH 5   505 332 HOH HOH C . 
O 4 HOH 6   506 268 HOH HOH C . 
O 4 HOH 7   507 44  HOH HOH C . 
O 4 HOH 8   508 92  HOH HOH C . 
O 4 HOH 9   509 218 HOH HOH C . 
O 4 HOH 10  510 76  HOH HOH C . 
O 4 HOH 11  511 181 HOH HOH C . 
O 4 HOH 12  512 275 HOH HOH C . 
O 4 HOH 13  513 97  HOH HOH C . 
O 4 HOH 14  514 237 HOH HOH C . 
O 4 HOH 15  515 22  HOH HOH C . 
O 4 HOH 16  516 232 HOH HOH C . 
O 4 HOH 17  517 137 HOH HOH C . 
O 4 HOH 18  518 132 HOH HOH C . 
O 4 HOH 19  519 30  HOH HOH C . 
O 4 HOH 20  520 361 HOH HOH C . 
O 4 HOH 21  521 350 HOH HOH C . 
O 4 HOH 22  522 344 HOH HOH C . 
O 4 HOH 23  523 48  HOH HOH C . 
O 4 HOH 24  524 166 HOH HOH C . 
O 4 HOH 25  525 202 HOH HOH C . 
O 4 HOH 26  526 29  HOH HOH C . 
O 4 HOH 27  527 188 HOH HOH C . 
O 4 HOH 28  528 173 HOH HOH C . 
O 4 HOH 29  529 260 HOH HOH C . 
O 4 HOH 30  530 157 HOH HOH C . 
O 4 HOH 31  531 120 HOH HOH C . 
O 4 HOH 32  532 115 HOH HOH C . 
O 4 HOH 33  533 63  HOH HOH C . 
O 4 HOH 34  534 289 HOH HOH C . 
O 4 HOH 35  535 7   HOH HOH C . 
O 4 HOH 36  536 207 HOH HOH C . 
O 4 HOH 37  537 2   HOH HOH C . 
O 4 HOH 38  538 66  HOH HOH C . 
O 4 HOH 39  539 326 HOH HOH C . 
O 4 HOH 40  540 169 HOH HOH C . 
O 4 HOH 41  541 224 HOH HOH C . 
O 4 HOH 42  542 323 HOH HOH C . 
O 4 HOH 43  543 165 HOH HOH C . 
O 4 HOH 44  544 52  HOH HOH C . 
O 4 HOH 45  545 69  HOH HOH C . 
O 4 HOH 46  546 13  HOH HOH C . 
O 4 HOH 47  547 317 HOH HOH C . 
O 4 HOH 48  548 24  HOH HOH C . 
O 4 HOH 49  549 297 HOH HOH C . 
O 4 HOH 50  550 5   HOH HOH C . 
O 4 HOH 51  551 259 HOH HOH C . 
O 4 HOH 52  552 50  HOH HOH C . 
O 4 HOH 53  553 219 HOH HOH C . 
O 4 HOH 54  554 43  HOH HOH C . 
O 4 HOH 55  555 246 HOH HOH C . 
O 4 HOH 56  556 31  HOH HOH C . 
O 4 HOH 57  557 177 HOH HOH C . 
O 4 HOH 58  558 200 HOH HOH C . 
O 4 HOH 59  559 80  HOH HOH C . 
O 4 HOH 60  560 152 HOH HOH C . 
O 4 HOH 61  561 131 HOH HOH C . 
O 4 HOH 62  562 206 HOH HOH C . 
O 4 HOH 63  563 347 HOH HOH C . 
O 4 HOH 64  564 84  HOH HOH C . 
O 4 HOH 65  565 73  HOH HOH C . 
O 4 HOH 66  566 318 HOH HOH C . 
O 4 HOH 67  567 226 HOH HOH C . 
O 4 HOH 68  568 319 HOH HOH C . 
O 4 HOH 69  569 142 HOH HOH C . 
O 4 HOH 70  570 82  HOH HOH C . 
O 4 HOH 71  571 14  HOH HOH C . 
O 4 HOH 72  572 223 HOH HOH C . 
O 4 HOH 73  573 330 HOH HOH C . 
O 4 HOH 74  574 274 HOH HOH C . 
O 4 HOH 75  575 154 HOH HOH C . 
O 4 HOH 76  576 118 HOH HOH C . 
O 4 HOH 77  577 314 HOH HOH C . 
O 4 HOH 78  578 364 HOH HOH C . 
O 4 HOH 79  579 170 HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 0 A TYR 154 ? CG  ? A TYR 154 CG  
2  1 Y 0 A TYR 154 ? CD1 ? A TYR 154 CD1 
3  1 Y 0 A TYR 154 ? CD2 ? A TYR 154 CD2 
4  1 Y 0 A TYR 154 ? CE1 ? A TYR 154 CE1 
5  1 Y 0 A TYR 154 ? CE2 ? A TYR 154 CE2 
6  1 Y 0 A TYR 154 ? CZ  ? A TYR 154 CZ  
7  1 Y 0 A TYR 154 ? OH  ? A TYR 154 OH  
8  1 Y 0 B TYR 154 ? CG  ? B TYR 154 CG  
9  1 Y 0 B TYR 154 ? CD1 ? B TYR 154 CD1 
10 1 Y 0 B TYR 154 ? CD2 ? B TYR 154 CD2 
11 1 Y 0 B TYR 154 ? CE1 ? B TYR 154 CE1 
12 1 Y 0 B TYR 154 ? CE2 ? B TYR 154 CE2 
13 1 Y 0 B TYR 154 ? CZ  ? B TYR 154 CZ  
14 1 Y 0 B TYR 154 ? OH  ? B TYR 154 OH  
15 1 Y 0 D TYR 154 ? CG  ? C TYR 154 CG  
16 1 Y 0 D TYR 154 ? CD1 ? C TYR 154 CD1 
17 1 Y 0 D TYR 154 ? CD2 ? C TYR 154 CD2 
18 1 Y 0 D TYR 154 ? CE1 ? C TYR 154 CE1 
19 1 Y 0 D TYR 154 ? CE2 ? C TYR 154 CE2 
20 1 Y 0 D TYR 154 ? CZ  ? C TYR 154 CZ  
21 1 Y 0 D TYR 154 ? OH  ? C TYR 154 OH  
22 1 Y 0 C TYR 154 ? CG  ? D TYR 154 CG  
23 1 Y 0 C TYR 154 ? CD1 ? D TYR 154 CD1 
24 1 Y 0 C TYR 154 ? CD2 ? D TYR 154 CD2 
25 1 Y 0 C TYR 154 ? CE1 ? D TYR 154 CE1 
26 1 Y 0 C TYR 154 ? CE2 ? D TYR 154 CE2 
27 1 Y 0 C TYR 154 ? CZ  ? D TYR 154 CZ  
28 1 Y 0 C TYR 154 ? OH  ? D TYR 154 OH  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5           2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALA  ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           5 
# 
_cell.angle_alpha                  85.61 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   80.43 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  78.65 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R26 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     45.488 
_cell.length_a_esd                 ? 
_cell.length_b                     71.464 
_cell.length_b_esd                 ? 
_cell.length_c                     85.795 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R26 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R26 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.99 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          38.14 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;0.1 BisTris
25% PEG3350
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            296 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-03-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0332 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0332 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8R26 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.3 
_reflns.d_resolution_low                               40.9 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     41704 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           89.79 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          6.96 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.993 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.30 
_reflns_shell.d_res_low                                     2.38 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.94 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4250 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.774 
_reflns_shell.pdbx_CC_star                                  0.934 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          91.20 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R26 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.30 
_refine.ls_d_res_low                             40.9 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     41635 
_refine.ls_number_reflns_R_free                  2020 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    89.80 
_refine.ls_percent_reflns_R_free                 4.85 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1947 
_refine.ls_R_factor_R_free                       0.2446 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1922 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.96 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.56 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.30 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        9444 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         175 
_refine_hist.number_atoms_solvent             365 
_refine_hist.number_atoms_total               9984 
_refine_hist.d_res_high                       2.30 
_refine_hist.d_res_low                        40.9 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.103  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 14.079 ? 3478 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.059  ? 1502 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.008  ? 1735 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.30 2.36 . . 152 2844 91.00 . . . . 0.2556 . . . . . . . . . . . 0.3416 
'X-RAY DIFFRACTION' 2.36 2.42 . . 134 2925 92.00 . . . . 0.2508 . . . . . . . . . . . 0.3186 
'X-RAY DIFFRACTION' 2.42 2.49 . . 152 2839 91.00 . . . . 0.2451 . . . . . . . . . . . 0.3241 
'X-RAY DIFFRACTION' 2.49 2.57 . . 134 2883 91.00 . . . . 0.2347 . . . . . . . . . . . 0.3124 
'X-RAY DIFFRACTION' 2.57 2.66 . . 163 2738 87.00 . . . . 0.2296 . . . . . . . . . . . 0.2725 
'X-RAY DIFFRACTION' 2.66 2.77 . . 131 2660 85.00 . . . . 0.2336 . . . . . . . . . . . 0.3047 
'X-RAY DIFFRACTION' 2.77 2.90 . . 131 2694 86.00 . . . . 0.2265 . . . . . . . . . . . 0.2915 
'X-RAY DIFFRACTION' 2.90 3.05 . . 169 2969 94.00 . . . . 0.2058 . . . . . . . . . . . 0.2374 
'X-RAY DIFFRACTION' 3.05 3.24 . . 150 2928 93.00 . . . . 0.1976 . . . . . . . . . . . 0.2609 
'X-RAY DIFFRACTION' 3.24 3.49 . . 138 2900 92.00 . . . . 0.1879 . . . . . . . . . . . 0.2290 
'X-RAY DIFFRACTION' 3.49 3.84 . . 135 2813 89.00 . . . . 0.1727 . . . . . . . . . . . 0.2150 
'X-RAY DIFFRACTION' 3.84 4.40 . . 147 2685 86.00 . . . . 0.1525 . . . . . . . . . . . 0.1988 
'X-RAY DIFFRACTION' 4.40 5.54 . . 154 2940 93.00 . . . . 0.1507 . . . . . . . . . . . 0.2025 
'X-RAY DIFFRACTION' 5.54 40.9 . . 130 2797 88.00 . . . . 0.1758 . . . . . . . . . . . 0.2132 
# 
_struct.entry_id                     8R26 
_struct.title                        'SARS-CoV-2 Mpro (Omicron,P132H) in complex with alpha-ketoamide 13b-K at pH 8.5' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R26 
_struct_keywords.text            
'SARS-CoV-2; main protease; Omicron; Molecular Dynamics; Pro>His mutant; double mutant, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 2 ? 
H N N 2 ? 
I N N 3 ? 
J N N 2 ? 
K N N 3 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1A_SARS2 
_struct_ref.pdbx_db_accession          P0DTC1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_struct_ref.pdbx_align_begin           3264 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R26 A 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
2 1 8R26 B 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
3 1 8R26 D 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
4 1 8R26 C 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R26 HIS A 132 ? UNP P0DTC1 PRO 3395 variant 132 1 
2 8R26 HIS B 132 ? UNP P0DTC1 PRO 3395 variant 132 2 
3 8R26 HIS D 132 ? UNP P0DTC1 PRO 3395 variant 132 3 
4 8R26 HIS C 132 ? UNP P0DTC1 PRO 3395 variant 132 4 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3260  ? 
1 MORE         -21   ? 
1 'SSA (A^2)'  25080 ? 
2 'ABSA (A^2)' 3370  ? 
2 MORE         -29   ? 
2 'SSA (A^2)'  24880 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,G,L,M   
2 1 C,D,H,I,J,K,N,O 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 15  ? SER A 10  GLY A 15  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 41  ? CYS A 44  ? HIS A 41  CYS A 44  5 ? 4  
HELX_P HELX_P3  AA3 SER A 46  ? LEU A 50  ? SER A 46  LEU A 50  5 ? 5  
HELX_P HELX_P4  AA4 ASN A 53  ? ARG A 60  ? ASN A 53  ARG A 60  1 ? 8  
HELX_P HELX_P5  AA5 SER A 62  ? PHE A 66  ? SER A 62  PHE A 66  5 ? 5  
HELX_P HELX_P6  AA6 ILE A 200 ? ASN A 214 ? ILE A 200 ASN A 214 1 ? 15 
HELX_P HELX_P7  AA7 THR A 226 ? TYR A 237 ? THR A 226 TYR A 237 1 ? 12 
HELX_P HELX_P8  AA8 THR A 243 ? LEU A 250 ? THR A 243 LEU A 250 1 ? 8  
HELX_P HELX_P9  AA9 LEU A 250 ? GLY A 258 ? LEU A 250 GLY A 258 1 ? 9  
HELX_P HELX_P10 AB1 ALA A 260 ? GLY A 275 ? ALA A 260 GLY A 275 1 ? 16 
HELX_P HELX_P11 AB2 THR A 292 ? GLY A 302 ? THR A 292 GLY A 302 1 ? 11 
HELX_P HELX_P12 AB3 SER B 10  ? GLY B 15  ? SER B 10  GLY B 15  1 ? 6  
HELX_P HELX_P13 AB4 HIS B 41  ? CYS B 44  ? HIS B 41  CYS B 44  5 ? 4  
HELX_P HELX_P14 AB5 SER B 46  ? LEU B 50  ? SER B 46  LEU B 50  5 ? 5  
HELX_P HELX_P15 AB6 ASN B 53  ? ARG B 60  ? ASN B 53  ARG B 60  1 ? 8  
HELX_P HELX_P16 AB7 LYS B 61  ? HIS B 64  ? LYS B 61  HIS B 64  5 ? 4  
HELX_P HELX_P17 AB8 ILE B 200 ? ASN B 214 ? ILE B 200 ASN B 214 1 ? 15 
HELX_P HELX_P18 AB9 THR B 226 ? TYR B 237 ? THR B 226 TYR B 237 1 ? 12 
HELX_P HELX_P19 AC1 THR B 243 ? LEU B 250 ? THR B 243 LEU B 250 1 ? 8  
HELX_P HELX_P20 AC2 LEU B 250 ? GLY B 258 ? LEU B 250 GLY B 258 1 ? 9  
HELX_P HELX_P21 AC3 ALA B 260 ? GLY B 275 ? ALA B 260 GLY B 275 1 ? 16 
HELX_P HELX_P22 AC4 THR B 292 ? GLY B 302 ? THR B 292 GLY B 302 1 ? 11 
HELX_P HELX_P23 AC5 SER C 10  ? GLY C 15  ? SER D 10  GLY D 15  1 ? 6  
HELX_P HELX_P24 AC6 HIS C 41  ? CYS C 44  ? HIS D 41  CYS D 44  5 ? 4  
HELX_P HELX_P25 AC7 SER C 46  ? LEU C 50  ? SER D 46  LEU D 50  5 ? 5  
HELX_P HELX_P26 AC8 ASN C 53  ? ARG C 60  ? ASN D 53  ARG D 60  1 ? 8  
HELX_P HELX_P27 AC9 SER C 62  ? PHE C 66  ? SER D 62  PHE D 66  5 ? 5  
HELX_P HELX_P28 AD1 ILE C 200 ? ASN C 214 ? ILE D 200 ASN D 214 1 ? 15 
HELX_P HELX_P29 AD2 THR C 226 ? TYR C 237 ? THR D 226 TYR D 237 1 ? 12 
HELX_P HELX_P30 AD3 THR C 243 ? LEU C 250 ? THR D 243 LEU D 250 1 ? 8  
HELX_P HELX_P31 AD4 LEU C 250 ? GLY C 258 ? LEU D 250 GLY D 258 1 ? 9  
HELX_P HELX_P32 AD5 ALA C 260 ? GLY C 275 ? ALA D 260 GLY D 275 1 ? 16 
HELX_P HELX_P33 AD6 THR C 292 ? GLY C 302 ? THR D 292 GLY D 302 1 ? 11 
HELX_P HELX_P34 AD7 SER D 10  ? GLY D 15  ? SER C 10  GLY C 15  1 ? 6  
HELX_P HELX_P35 AD8 HIS D 41  ? CYS D 44  ? HIS C 41  CYS C 44  5 ? 4  
HELX_P HELX_P36 AD9 SER D 46  ? LEU D 50  ? SER C 46  LEU C 50  5 ? 5  
HELX_P HELX_P37 AE1 ASN D 53  ? ARG D 60  ? ASN C 53  ARG C 60  1 ? 8  
HELX_P HELX_P38 AE2 LYS D 61  ? PHE D 66  ? LYS C 61  PHE C 66  5 ? 6  
HELX_P HELX_P39 AE3 ILE D 200 ? ASN D 214 ? ILE C 200 ASN C 214 1 ? 15 
HELX_P HELX_P40 AE4 THR D 226 ? TYR D 237 ? THR C 226 TYR C 237 1 ? 12 
HELX_P HELX_P41 AE5 THR D 243 ? LEU D 250 ? THR C 243 LEU C 250 1 ? 8  
HELX_P HELX_P42 AE6 LEU D 250 ? GLY D 258 ? LEU C 250 GLY C 258 1 ? 9  
HELX_P HELX_P43 AE7 ALA D 260 ? GLY D 275 ? ALA C 260 GLY C 275 1 ? 16 
HELX_P HELX_P44 AE8 THR D 292 ? GLY D 302 ? THR C 292 GLY C 302 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A CYS 145 SG ? ? ? 1_555 E O6K . C57 ? ? A CYS 145 A O6K 401 1_555 ? ? ? ? ? ? ? 1.765 ? ? 
covale2 covale none ? B CYS 145 SG ? ? ? 1_555 G O6K . C57 ? ? B CYS 145 B O6K 401 1_555 ? ? ? ? ? ? ? 1.768 ? ? 
covale3 covale none ? C CYS 145 SG ? ? ? 1_555 H O6K . C57 ? ? D CYS 145 D O6K 401 1_555 ? ? ? ? ? ? ? 1.767 ? ? 
covale4 covale none ? D CYS 145 SG ? ? ? 1_555 J O6K . C57 ? ? C CYS 145 C O6K 401 1_555 ? ? ? ? ? ? ? 1.769 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 O6K E . ? CYS A 145 ? O6K A 401 ? 1_555 CYS A 145 ? 1_555 C57 SG CYS 1 O6K None 'Covalent chemical modification' 
2 O6K G . ? CYS B 145 ? O6K B 401 ? 1_555 CYS B 145 ? 1_555 C57 SG CYS 1 O6K None 'Covalent chemical modification' 
3 O6K H . ? CYS C 145 ? O6K D 401 ? 1_555 CYS D 145 ? 1_555 C57 SG CYS 1 O6K None 'Covalent chemical modification' 
4 O6K J . ? CYS D 145 ? O6K C 401 ? 1_555 CYS C 145 ? 1_555 C57 SG CYS 1 O6K None 'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
AA7 ? 7 ? 
AA8 ? 5 ? 
AA9 ? 3 ? 
AB1 ? 7 ? 
AB2 ? 5 ? 
AB3 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA7 5 6 ? anti-parallel 
AA7 6 7 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 73  ? LEU A 75  ? VAL A 73  LEU A 75  
AA1 2 LEU A 67  ? ALA A 70  ? LEU A 67  ALA A 70  
AA1 3 MET A 17  ? CYS A 22  ? MET A 17  CYS A 22  
AA1 4 THR A 25  ? LEU A 32  ? THR A 25  LEU A 32  
AA1 5 VAL A 35  ? PRO A 39  ? VAL A 35  PRO A 39  
AA1 6 VAL A 86  ? VAL A 91  ? VAL A 86  VAL A 91  
AA1 7 VAL A 77  ? GLN A 83  ? VAL A 77  GLN A 83  
AA2 1 TYR A 101 ? PHE A 103 ? TYR A 101 PHE A 103 
AA2 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA2 3 VAL A 148 ? ASP A 153 ? VAL A 148 ASP A 153 
AA2 4 THR A 111 ? TYR A 118 ? THR A 111 TYR A 118 
AA2 5 SER A 121 ? ALA A 129 ? SER A 121 ALA A 129 
AA3 1 TYR A 101 ? PHE A 103 ? TYR A 101 PHE A 103 
AA3 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA3 3 VAL A 171 ? THR A 175 ? VAL A 171 THR A 175 
AA4 1 VAL B 73  ? LEU B 75  ? VAL B 73  LEU B 75  
AA4 2 PHE B 66  ? ALA B 70  ? PHE B 66  ALA B 70  
AA4 3 MET B 17  ? CYS B 22  ? MET B 17  CYS B 22  
AA4 4 THR B 25  ? LEU B 32  ? THR B 25  LEU B 32  
AA4 5 VAL B 35  ? PRO B 39  ? VAL B 35  PRO B 39  
AA4 6 VAL B 86  ? VAL B 91  ? VAL B 86  VAL B 91  
AA4 7 VAL B 77  ? GLN B 83  ? VAL B 77  GLN B 83  
AA5 1 TYR B 101 ? PHE B 103 ? TYR B 101 PHE B 103 
AA5 2 CYS B 156 ? LEU B 167 ? CYS B 156 LEU B 167 
AA5 3 VAL B 148 ? ASP B 153 ? VAL B 148 ASP B 153 
AA5 4 THR B 111 ? TYR B 118 ? THR B 111 TYR B 118 
AA5 5 SER B 121 ? ALA B 129 ? SER B 121 ALA B 129 
AA6 1 TYR B 101 ? PHE B 103 ? TYR B 101 PHE B 103 
AA6 2 CYS B 156 ? LEU B 167 ? CYS B 156 LEU B 167 
AA6 3 VAL B 171 ? THR B 175 ? VAL B 171 THR B 175 
AA7 1 VAL C 73  ? LEU C 75  ? VAL D 73  LEU D 75  
AA7 2 LEU C 67  ? ALA C 70  ? LEU D 67  ALA D 70  
AA7 3 MET C 17  ? CYS C 22  ? MET D 17  CYS D 22  
AA7 4 THR C 25  ? LEU C 32  ? THR D 25  LEU D 32  
AA7 5 VAL C 35  ? PRO C 39  ? VAL D 35  PRO D 39  
AA7 6 VAL C 86  ? VAL C 91  ? VAL D 86  VAL D 91  
AA7 7 VAL C 77  ? GLN C 83  ? VAL D 77  GLN D 83  
AA8 1 TYR C 101 ? PHE C 103 ? TYR D 101 PHE D 103 
AA8 2 CYS C 156 ? GLU C 166 ? CYS D 156 GLU D 166 
AA8 3 VAL C 148 ? ASP C 153 ? VAL D 148 ASP D 153 
AA8 4 THR C 111 ? TYR C 118 ? THR D 111 TYR D 118 
AA8 5 SER C 121 ? ALA C 129 ? SER D 121 ALA D 129 
AA9 1 TYR C 101 ? PHE C 103 ? TYR D 101 PHE D 103 
AA9 2 CYS C 156 ? GLU C 166 ? CYS D 156 GLU D 166 
AA9 3 HIS C 172 ? THR C 175 ? HIS D 172 THR D 175 
AB1 1 VAL D 73  ? LEU D 75  ? VAL C 73  LEU C 75  
AB1 2 LEU D 67  ? ALA D 70  ? LEU C 67  ALA C 70  
AB1 3 MET D 17  ? CYS D 22  ? MET C 17  CYS C 22  
AB1 4 THR D 25  ? LEU D 32  ? THR C 25  LEU C 32  
AB1 5 VAL D 35  ? PRO D 39  ? VAL C 35  PRO C 39  
AB1 6 VAL D 86  ? VAL D 91  ? VAL C 86  VAL C 91  
AB1 7 VAL D 77  ? GLN D 83  ? VAL C 77  GLN C 83  
AB2 1 TYR D 101 ? PHE D 103 ? TYR C 101 PHE C 103 
AB2 2 CYS D 156 ? LEU D 167 ? CYS C 156 LEU C 167 
AB2 3 VAL D 148 ? ASP D 153 ? VAL C 148 ASP C 153 
AB2 4 THR D 111 ? TYR D 118 ? THR C 111 TYR C 118 
AB2 5 SER D 121 ? ALA D 129 ? SER C 121 ALA C 129 
AB3 1 TYR D 101 ? PHE D 103 ? TYR C 101 PHE C 103 
AB3 2 CYS D 156 ? LEU D 167 ? CYS C 156 LEU C 167 
AB3 3 VAL D 171 ? THR D 175 ? VAL C 171 THR C 175 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 75  ? O LEU A 75  N VAL A 68  ? N VAL A 68  
AA1 2 3 O LEU A 67  ? O LEU A 67  N THR A 21  ? N THR A 21  
AA1 3 4 N VAL A 20  ? N VAL A 20  O LEU A 27  ? O LEU A 27  
AA1 4 5 N LEU A 30  ? N LEU A 30  O TYR A 37  ? O TYR A 37  
AA1 5 6 N CYS A 38  ? N CYS A 38  O LEU A 87  ? O LEU A 87  
AA1 6 7 O LYS A 90  ? O LYS A 90  N ILE A 78  ? N ILE A 78  
AA2 1 2 N LYS A 102 ? N LYS A 102 O PHE A 159 ? O PHE A 159 
AA2 2 3 O SER A 158 ? O SER A 158 N ASN A 151 ? N ASN A 151 
AA2 3 4 O PHE A 150 ? O PHE A 150 N SER A 113 ? N SER A 113 
AA2 4 5 N VAL A 114 ? N VAL A 114 O TYR A 126 ? O TYR A 126 
AA3 1 2 N LYS A 102 ? N LYS A 102 O PHE A 159 ? O PHE A 159 
AA3 2 3 N LEU A 167 ? N LEU A 167 O VAL A 171 ? O VAL A 171 
AA4 1 2 O LEU B 75  ? O LEU B 75  N VAL B 68  ? N VAL B 68  
AA4 2 3 O LEU B 67  ? O LEU B 67  N THR B 21  ? N THR B 21  
AA4 3 4 N VAL B 20  ? N VAL B 20  O LEU B 27  ? O LEU B 27  
AA4 4 5 N LEU B 32  ? N LEU B 32  O VAL B 35  ? O VAL B 35  
AA4 5 6 N CYS B 38  ? N CYS B 38  O LEU B 87  ? O LEU B 87  
AA4 6 7 O LYS B 88  ? O LYS B 88  N SER B 81  ? N SER B 81  
AA5 1 2 N LYS B 102 ? N LYS B 102 O PHE B 159 ? O PHE B 159 
AA5 2 3 O SER B 158 ? O SER B 158 N ASN B 151 ? N ASN B 151 
AA5 3 4 O PHE B 150 ? O PHE B 150 N SER B 113 ? N SER B 113 
AA5 4 5 N ALA B 116 ? N ALA B 116 O SER B 123 ? O SER B 123 
AA6 1 2 N LYS B 102 ? N LYS B 102 O PHE B 159 ? O PHE B 159 
AA6 2 3 N LEU B 167 ? N LEU B 167 O VAL B 171 ? O VAL B 171 
AA7 1 2 O LEU C 75  ? O LEU D 75  N VAL C 68  ? N VAL D 68  
AA7 2 3 O LEU C 67  ? O LEU D 67  N THR C 21  ? N THR D 21  
AA7 3 4 N VAL C 20  ? N VAL D 20  O LEU C 27  ? O LEU D 27  
AA7 4 5 N LEU C 30  ? N LEU D 30  O TYR C 37  ? O TYR D 37  
AA7 5 6 N CYS C 38  ? N CYS D 38  O LEU C 87  ? O LEU D 87  
AA7 6 7 O LYS C 88  ? O LYS D 88  N SER C 81  ? N SER D 81  
AA8 1 2 N LYS C 102 ? N LYS D 102 O PHE C 159 ? O PHE D 159 
AA8 2 3 O SER C 158 ? O SER D 158 N ASN C 151 ? N ASN D 151 
AA8 3 4 O PHE C 150 ? O PHE D 150 N SER C 113 ? N SER D 113 
AA8 4 5 N VAL C 114 ? N VAL D 114 O TYR C 126 ? O TYR D 126 
AA9 1 2 N LYS C 102 ? N LYS D 102 O PHE C 159 ? O PHE D 159 
AA9 2 3 N MET C 165 ? N MET D 165 O ALA C 173 ? O ALA D 173 
AB1 1 2 O VAL D 73  ? O VAL C 73  N ALA D 70  ? N ALA C 70  
AB1 2 3 O LEU D 67  ? O LEU C 67  N THR D 21  ? N THR C 21  
AB1 3 4 N CYS D 22  ? N CYS C 22  O THR D 25  ? O THR C 25  
AB1 4 5 N LEU D 30  ? N LEU C 30  O TYR D 37  ? O TYR C 37  
AB1 5 6 N CYS D 38  ? N CYS C 38  O LEU D 87  ? O LEU C 87  
AB1 6 7 O LYS D 88  ? O LYS C 88  N SER D 81  ? N SER C 81  
AB2 1 2 N LYS D 102 ? N LYS C 102 O PHE D 159 ? O PHE C 159 
AB2 2 3 O SER D 158 ? O SER C 158 N ASN D 151 ? N ASN C 151 
AB2 3 4 O PHE D 150 ? O PHE C 150 N SER D 113 ? N SER C 113 
AB2 4 5 N ALA D 116 ? N ALA C 116 O SER D 123 ? O SER C 123 
AB3 1 2 N LYS D 102 ? N LYS C 102 O PHE D 159 ? O PHE C 159 
AB3 2 3 N LEU D 167 ? N LEU C 167 O VAL D 171 ? O VAL C 171 
# 
_pdbx_entry_details.entry_id                   8R26 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1 D ASP 155 ? ? O D HOH 501 ? ? 1.81 
2  1 O   D PHE 66  ? ? O D HOH 502 ? ? 1.84 
3  1 O   D HOH 587 ? ? O D HOH 589 ? ? 1.86 
4  1 OD1 B ASP 92  ? ? O B HOH 501 ? ? 1.89 
5  1 SG  A CYS 128 ? ? O A HOH 508 ? ? 1.90 
6  1 OG1 B THR 93  ? ? O B HOH 501 ? ? 1.91 
7  1 OG1 C THR 243 ? ? O C HOH 501 ? ? 1.91 
8  1 C   A CYS 128 ? ? O A HOH 508 ? ? 1.93 
9  1 O   B HOH 508 ? ? O B HOH 585 ? ? 1.93 
10 1 O   B ALA 194 ? ? O B HOH 502 ? ? 1.97 
11 1 OG1 A THR 45  ? ? O A HOH 501 ? ? 1.98 
12 1 O   B HOH 502 ? ? O B HOH 583 ? ? 1.99 
13 1 NH2 C ARG 298 ? ? O C HOH 502 ? ? 1.99 
14 1 OH  C TYR 154 ? ? O C HOH 503 ? ? 2.00 
15 1 OD1 A ASP 197 ? ? O A HOH 502 ? ? 2.00 
16 1 NH2 D ARG 217 ? ? O D HOH 503 ? ? 2.01 
17 1 NZ  C LYS 88  ? ? O C HOH 504 ? ? 2.02 
18 1 OD1 C ASN 277 ? ? O C HOH 505 ? ? 2.02 
19 1 O   D HOH 561 ? ? O D HOH 577 ? ? 2.03 
20 1 O   A HOH 521 ? ? O D HOH 569 ? ? 2.05 
21 1 O   B HOH 553 ? ? O B HOH 588 ? ? 2.05 
22 1 O   B LYS 5   ? ? O B HOH 503 ? ? 2.06 
23 1 O   B CYS 156 ? ? O B HOH 504 ? ? 2.08 
24 1 OE1 A GLU 288 ? ? O A HOH 503 ? ? 2.10 
25 1 OE1 C GLN 69  ? ? O C HOH 506 ? ? 2.10 
26 1 OD1 B ASP 248 ? ? O B HOH 505 ? ? 2.11 
27 1 CA  A CYS 128 ? ? O A HOH 508 ? ? 2.12 
28 1 CB  A CYS 128 ? ? O A HOH 508 ? ? 2.13 
29 1 O   A GLY 23  ? ? O A HOH 504 ? ? 2.13 
30 1 O   C GLN 19  ? ? O C HOH 507 ? ? 2.13 
31 1 O   A VAL 212 ? ? O A HOH 505 ? ? 2.14 
32 1 NE  D ARG 217 ? ? O D HOH 503 ? ? 2.14 
33 1 O   C HOH 567 ? ? O C HOH 578 ? ? 2.14 
34 1 O   A HOH 503 ? ? O A HOH 590 ? ? 2.14 
35 1 O   C LYS 97  ? ? O C HOH 508 ? ? 2.15 
36 1 O   B HOH 589 ? ? O B HOH 593 ? ? 2.16 
37 1 OE2 A GLU 178 ? ? O A HOH 506 ? ? 2.16 
38 1 O   C HOH 536 ? ? O C HOH 562 ? ? 2.19 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    CL 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    CL 
_pdbx_validate_symm_contact.auth_seq_id_1     402 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    D 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     583 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   1_655 
_pdbx_validate_symm_contact.dist              1.84 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 33  ? ? 55.14   -125.95 
2  1 ASP A 48  ? ? -76.18  33.66   
3  1 ASN A 84  ? ? 49.53   -119.22 
4  1 TYR A 154 ? ? 59.00   -93.62  
5  1 ASP B 33  ? ? 56.30   -127.33 
6  1 ASP B 48  ? ? -76.86  31.48   
7  1 ASN B 84  ? ? 48.89   -116.24 
8  1 TYR B 154 ? ? 61.92   -99.79  
9  1 HIS B 164 ? ? -130.21 -40.60  
10 1 ASP D 33  ? ? 55.77   -127.19 
11 1 ASP D 48  ? ? -77.99  30.65   
12 1 ASN D 51  ? ? -150.20 81.30   
13 1 ASN D 84  ? ? 51.26   -117.70 
14 1 TYR D 154 ? ? 60.55   -96.29  
15 1 ASP C 33  ? ? 54.21   -126.21 
16 1 ASP C 48  ? ? -78.41  31.92   
17 1 ASN C 84  ? ? 50.13   -115.91 
18 1 TYR C 154 ? ? 60.41   -95.40  
19 1 HIS C 164 ? ? -131.20 -42.22  
# 
_pdbx_validate_main_chain_plane.id                       1 
_pdbx_validate_main_chain_plane.PDB_model_num            1 
_pdbx_validate_main_chain_plane.auth_comp_id             GLU 
_pdbx_validate_main_chain_plane.auth_asym_id             B 
_pdbx_validate_main_chain_plane.auth_seq_id              240 
_pdbx_validate_main_chain_plane.PDB_ins_code             ? 
_pdbx_validate_main_chain_plane.label_alt_id             B 
_pdbx_validate_main_chain_plane.improper_torsion_angle   10.63 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? B HOH 593 ? 5.95 . 
2 1 O ? D HOH 589 ? 5.92 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLN 306 ? A GLN 306 
2 1 Y 1 B GLN 306 ? B GLN 306 
3 1 Y 1 D GLN 306 ? C GLN 306 
4 1 Y 1 C GLN 306 ? D GLN 306 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
O6K O26  O  N N 251 
O6K C24  C  N N 252 
O6K O25  O  N N 253 
O6K C27  C  N N 254 
O6K C31  C  N N 255 
O6K C32  C  N N 256 
O6K C33  C  N N 257 
O6K N23  N  N N 258 
O6K C19  C  N N 259 
O6K C21  C  N N 260 
O6K O22  O  N N 261 
O6K C18  C  N N 262 
O6K C17  C  N N 263 
O6K C16  C  N N 264 
O6K N15  N  N N 265 
O6K C20  C  N S 266 
O6K C22  C  N N 267 
O6K C29  C  N N 268 
O6K C34  C  N N 269 
O6K C30  C  N N 270 
O6K C36  C  N N 271 
O6K O37  O  N N 272 
O6K N38  N  N N 273 
O6K C40  C  N S 274 
O6K C42  C  N N 275 
O6K C45  C  N S 276 
O6K C47  C  N N 277 
O6K O48  O  N N 278 
O6K N49  N  N N 279 
O6K C51  C  N N 280 
O6K C54  C  N N 281 
O6K C57  C  N R 282 
O6K O40  O  N N 283 
O6K C35  C  N N 284 
O6K O41  O  N N 285 
O6K N36  N  N N 286 
O6K C13  C  N N 287 
O6K C14  C  Y N 288 
O6K C28  C  Y N 289 
O6K C26  C  Y N 290 
O6K C25  C  Y N 291 
O6K C23  C  Y N 292 
O6K C15  C  Y N 293 
O6K H1   H  N N 294 
O6K H2   H  N N 295 
O6K H3   H  N N 296 
O6K H4   H  N N 297 
O6K H5   H  N N 298 
O6K H6   H  N N 299 
O6K H7   H  N N 300 
O6K H8   H  N N 301 
O6K H9   H  N N 302 
O6K H10  H  N N 303 
O6K H11  H  N N 304 
O6K H12  H  N N 305 
O6K H13  H  N N 306 
O6K H14  H  N N 307 
O6K H15  H  N N 308 
O6K H16  H  N N 309 
O6K H17  H  N N 310 
O6K H18  H  N N 311 
O6K H19  H  N N 312 
O6K H20  H  N N 313 
O6K H21  H  N N 314 
O6K H22  H  N N 315 
O6K H23  H  N N 316 
O6K H24  H  N N 317 
O6K H25  H  N N 318 
O6K H26  H  N N 319 
O6K H27  H  N N 320 
O6K H28  H  N N 321 
O6K H29  H  N N 322 
O6K H30  H  N N 323 
O6K H31  H  N N 324 
O6K H34  H  N N 325 
O6K H35  H  N N 326 
O6K H36  H  N N 327 
O6K H37  H  N N 328 
O6K H38  H  N N 329 
O6K H39  H  N N 330 
O6K H40  H  N N 331 
O6K H41  H  N N 332 
O6K H32  H  N N 333 
O6K H33  H  N N 334 
PHE N    N  N N 335 
PHE CA   C  N S 336 
PHE C    C  N N 337 
PHE O    O  N N 338 
PHE CB   C  N N 339 
PHE CG   C  Y N 340 
PHE CD1  C  Y N 341 
PHE CD2  C  Y N 342 
PHE CE1  C  Y N 343 
PHE CE2  C  Y N 344 
PHE CZ   C  Y N 345 
PHE OXT  O  N N 346 
PHE H    H  N N 347 
PHE H2   H  N N 348 
PHE HA   H  N N 349 
PHE HB2  H  N N 350 
PHE HB3  H  N N 351 
PHE HD1  H  N N 352 
PHE HD2  H  N N 353 
PHE HE1  H  N N 354 
PHE HE2  H  N N 355 
PHE HZ   H  N N 356 
PHE HXT  H  N N 357 
PRO N    N  N N 358 
PRO CA   C  N S 359 
PRO C    C  N N 360 
PRO O    O  N N 361 
PRO CB   C  N N 362 
PRO CG   C  N N 363 
PRO CD   C  N N 364 
PRO OXT  O  N N 365 
PRO H    H  N N 366 
PRO HA   H  N N 367 
PRO HB2  H  N N 368 
PRO HB3  H  N N 369 
PRO HG2  H  N N 370 
PRO HG3  H  N N 371 
PRO HD2  H  N N 372 
PRO HD3  H  N N 373 
PRO HXT  H  N N 374 
SER N    N  N N 375 
SER CA   C  N S 376 
SER C    C  N N 377 
SER O    O  N N 378 
SER CB   C  N N 379 
SER OG   O  N N 380 
SER OXT  O  N N 381 
SER H    H  N N 382 
SER H2   H  N N 383 
SER HA   H  N N 384 
SER HB2  H  N N 385 
SER HB3  H  N N 386 
SER HG   H  N N 387 
SER HXT  H  N N 388 
THR N    N  N N 389 
THR CA   C  N S 390 
THR C    C  N N 391 
THR O    O  N N 392 
THR CB   C  N R 393 
THR OG1  O  N N 394 
THR CG2  C  N N 395 
THR OXT  O  N N 396 
THR H    H  N N 397 
THR H2   H  N N 398 
THR HA   H  N N 399 
THR HB   H  N N 400 
THR HG1  H  N N 401 
THR HG21 H  N N 402 
THR HG22 H  N N 403 
THR HG23 H  N N 404 
THR HXT  H  N N 405 
TRP N    N  N N 406 
TRP CA   C  N S 407 
TRP C    C  N N 408 
TRP O    O  N N 409 
TRP CB   C  N N 410 
TRP CG   C  Y N 411 
TRP CD1  C  Y N 412 
TRP CD2  C  Y N 413 
TRP NE1  N  Y N 414 
TRP CE2  C  Y N 415 
TRP CE3  C  Y N 416 
TRP CZ2  C  Y N 417 
TRP CZ3  C  Y N 418 
TRP CH2  C  Y N 419 
TRP OXT  O  N N 420 
TRP H    H  N N 421 
TRP H2   H  N N 422 
TRP HA   H  N N 423 
TRP HB2  H  N N 424 
TRP HB3  H  N N 425 
TRP HD1  H  N N 426 
TRP HE1  H  N N 427 
TRP HE3  H  N N 428 
TRP HZ2  H  N N 429 
TRP HZ3  H  N N 430 
TRP HH2  H  N N 431 
TRP HXT  H  N N 432 
TYR N    N  N N 433 
TYR CA   C  N S 434 
TYR C    C  N N 435 
TYR O    O  N N 436 
TYR CB   C  N N 437 
TYR CG   C  Y N 438 
TYR CD1  C  Y N 439 
TYR CD2  C  Y N 440 
TYR CE1  C  Y N 441 
TYR CE2  C  Y N 442 
TYR CZ   C  Y N 443 
TYR OH   O  N N 444 
TYR OXT  O  N N 445 
TYR H    H  N N 446 
TYR H2   H  N N 447 
TYR HA   H  N N 448 
TYR HB2  H  N N 449 
TYR HB3  H  N N 450 
TYR HD1  H  N N 451 
TYR HD2  H  N N 452 
TYR HE1  H  N N 453 
TYR HE2  H  N N 454 
TYR HH   H  N N 455 
TYR HXT  H  N N 456 
VAL N    N  N N 457 
VAL CA   C  N S 458 
VAL C    C  N N 459 
VAL O    O  N N 460 
VAL CB   C  N N 461 
VAL CG1  C  N N 462 
VAL CG2  C  N N 463 
VAL OXT  O  N N 464 
VAL H    H  N N 465 
VAL H2   H  N N 466 
VAL HA   H  N N 467 
VAL HB   H  N N 468 
VAL HG11 H  N N 469 
VAL HG12 H  N N 470 
VAL HG13 H  N N 471 
VAL HG21 H  N N 472 
VAL HG22 H  N N 473 
VAL HG23 H  N N 474 
VAL HXT  H  N N 475 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
O6K N49 C47  sing N N 237 
O6K N49 C51  sing N N 238 
O6K O48 C47  doub N N 239 
O6K C47 C45  sing N N 240 
O6K C51 C54  sing N N 241 
O6K O41 C35  doub N N 242 
O6K C54 C45  sing N N 243 
O6K C45 C42  sing N N 244 
O6K C42 C40  sing N N 245 
O6K C23 C15  doub Y N 246 
O6K C23 C25  sing Y N 247 
O6K C15 C14  sing Y N 248 
O6K C25 C26  doub Y N 249 
O6K C35 N36  sing N N 250 
O6K C35 C57  sing N N 251 
O6K C14 C13  sing N N 252 
O6K C14 C28  doub Y N 253 
O6K C13 N36  sing N N 254 
O6K C26 C28  sing Y N 255 
O6K C40 C57  sing N N 256 
O6K C40 N38  sing N N 257 
O6K C57 O40  sing N N 258 
O6K C32 C27  sing N N 259 
O6K N38 C36  sing N N 260 
O6K C33 C27  sing N N 261 
O6K C27 O25  sing N N 262 
O6K C27 C31  sing N N 263 
O6K O25 C24  sing N N 264 
O6K O37 C36  doub N N 265 
O6K O22 C21  doub N N 266 
O6K C36 C20  sing N N 267 
O6K N23 C24  sing N N 268 
O6K N23 C19  sing N N 269 
O6K C24 O26  doub N N 270 
O6K C21 C19  sing N N 271 
O6K C21 N15  sing N N 272 
O6K C20 N15  sing N N 273 
O6K C20 C22  sing N N 274 
O6K C19 C18  doub N N 275 
O6K N15 C16  sing N N 276 
O6K C22 C29  sing N N 277 
O6K C18 C17  sing N N 278 
O6K C16 C17  doub N N 279 
O6K C30 C29  sing N N 280 
O6K C30 C34  sing N N 281 
O6K C29 C34  sing N N 282 
O6K C31 H1   sing N N 283 
O6K C31 H2   sing N N 284 
O6K C31 H3   sing N N 285 
O6K C32 H4   sing N N 286 
O6K C32 H5   sing N N 287 
O6K C32 H6   sing N N 288 
O6K C33 H7   sing N N 289 
O6K C33 H8   sing N N 290 
O6K C33 H9   sing N N 291 
O6K N23 H10  sing N N 292 
O6K C18 H11  sing N N 293 
O6K C17 H12  sing N N 294 
O6K C16 H13  sing N N 295 
O6K C20 H14  sing N N 296 
O6K C22 H15  sing N N 297 
O6K C22 H16  sing N N 298 
O6K C29 H17  sing N N 299 
O6K C34 H18  sing N N 300 
O6K C34 H19  sing N N 301 
O6K C30 H20  sing N N 302 
O6K C30 H21  sing N N 303 
O6K N38 H22  sing N N 304 
O6K C40 H23  sing N N 305 
O6K C42 H24  sing N N 306 
O6K C42 H25  sing N N 307 
O6K C45 H26  sing N N 308 
O6K N49 H27  sing N N 309 
O6K C51 H28  sing N N 310 
O6K C51 H29  sing N N 311 
O6K C54 H30  sing N N 312 
O6K C54 H31  sing N N 313 
O6K N36 H34  sing N N 314 
O6K C13 H35  sing N N 315 
O6K C13 H36  sing N N 316 
O6K C28 H37  sing N N 317 
O6K C26 H38  sing N N 318 
O6K C25 H39  sing N N 319 
O6K C23 H40  sing N N 320 
O6K C15 H41  sing N N 321 
O6K C57 H32  sing N N 322 
O6K O40 H33  sing N N 323 
PHE N   CA   sing N N 324 
PHE N   H    sing N N 325 
PHE N   H2   sing N N 326 
PHE CA  C    sing N N 327 
PHE CA  CB   sing N N 328 
PHE CA  HA   sing N N 329 
PHE C   O    doub N N 330 
PHE C   OXT  sing N N 331 
PHE CB  CG   sing N N 332 
PHE CB  HB2  sing N N 333 
PHE CB  HB3  sing N N 334 
PHE CG  CD1  doub Y N 335 
PHE CG  CD2  sing Y N 336 
PHE CD1 CE1  sing Y N 337 
PHE CD1 HD1  sing N N 338 
PHE CD2 CE2  doub Y N 339 
PHE CD2 HD2  sing N N 340 
PHE CE1 CZ   doub Y N 341 
PHE CE1 HE1  sing N N 342 
PHE CE2 CZ   sing Y N 343 
PHE CE2 HE2  sing N N 344 
PHE CZ  HZ   sing N N 345 
PHE OXT HXT  sing N N 346 
PRO N   CA   sing N N 347 
PRO N   CD   sing N N 348 
PRO N   H    sing N N 349 
PRO CA  C    sing N N 350 
PRO CA  CB   sing N N 351 
PRO CA  HA   sing N N 352 
PRO C   O    doub N N 353 
PRO C   OXT  sing N N 354 
PRO CB  CG   sing N N 355 
PRO CB  HB2  sing N N 356 
PRO CB  HB3  sing N N 357 
PRO CG  CD   sing N N 358 
PRO CG  HG2  sing N N 359 
PRO CG  HG3  sing N N 360 
PRO CD  HD2  sing N N 361 
PRO CD  HD3  sing N N 362 
PRO OXT HXT  sing N N 363 
SER N   CA   sing N N 364 
SER N   H    sing N N 365 
SER N   H2   sing N N 366 
SER CA  C    sing N N 367 
SER CA  CB   sing N N 368 
SER CA  HA   sing N N 369 
SER C   O    doub N N 370 
SER C   OXT  sing N N 371 
SER CB  OG   sing N N 372 
SER CB  HB2  sing N N 373 
SER CB  HB3  sing N N 374 
SER OG  HG   sing N N 375 
SER OXT HXT  sing N N 376 
THR N   CA   sing N N 377 
THR N   H    sing N N 378 
THR N   H2   sing N N 379 
THR CA  C    sing N N 380 
THR CA  CB   sing N N 381 
THR CA  HA   sing N N 382 
THR C   O    doub N N 383 
THR C   OXT  sing N N 384 
THR CB  OG1  sing N N 385 
THR CB  CG2  sing N N 386 
THR CB  HB   sing N N 387 
THR OG1 HG1  sing N N 388 
THR CG2 HG21 sing N N 389 
THR CG2 HG22 sing N N 390 
THR CG2 HG23 sing N N 391 
THR OXT HXT  sing N N 392 
TRP N   CA   sing N N 393 
TRP N   H    sing N N 394 
TRP N   H2   sing N N 395 
TRP CA  C    sing N N 396 
TRP CA  CB   sing N N 397 
TRP CA  HA   sing N N 398 
TRP C   O    doub N N 399 
TRP C   OXT  sing N N 400 
TRP CB  CG   sing N N 401 
TRP CB  HB2  sing N N 402 
TRP CB  HB3  sing N N 403 
TRP CG  CD1  doub Y N 404 
TRP CG  CD2  sing Y N 405 
TRP CD1 NE1  sing Y N 406 
TRP CD1 HD1  sing N N 407 
TRP CD2 CE2  doub Y N 408 
TRP CD2 CE3  sing Y N 409 
TRP NE1 CE2  sing Y N 410 
TRP NE1 HE1  sing N N 411 
TRP CE2 CZ2  sing Y N 412 
TRP CE3 CZ3  doub Y N 413 
TRP CE3 HE3  sing N N 414 
TRP CZ2 CH2  doub Y N 415 
TRP CZ2 HZ2  sing N N 416 
TRP CZ3 CH2  sing Y N 417 
TRP CZ3 HZ3  sing N N 418 
TRP CH2 HH2  sing N N 419 
TRP OXT HXT  sing N N 420 
TYR N   CA   sing N N 421 
TYR N   H    sing N N 422 
TYR N   H2   sing N N 423 
TYR CA  C    sing N N 424 
TYR CA  CB   sing N N 425 
TYR CA  HA   sing N N 426 
TYR C   O    doub N N 427 
TYR C   OXT  sing N N 428 
TYR CB  CG   sing N N 429 
TYR CB  HB2  sing N N 430 
TYR CB  HB3  sing N N 431 
TYR CG  CD1  doub Y N 432 
TYR CG  CD2  sing Y N 433 
TYR CD1 CE1  sing Y N 434 
TYR CD1 HD1  sing N N 435 
TYR CD2 CE2  doub Y N 436 
TYR CD2 HD2  sing N N 437 
TYR CE1 CZ   doub Y N 438 
TYR CE1 HE1  sing N N 439 
TYR CE2 CZ   sing Y N 440 
TYR CE2 HE2  sing N N 441 
TYR CZ  OH   sing N N 442 
TYR OH  HH   sing N N 443 
TYR OXT HXT  sing N N 444 
VAL N   CA   sing N N 445 
VAL N   H    sing N N 446 
VAL N   H2   sing N N 447 
VAL CA  C    sing N N 448 
VAL CA  CB   sing N N 449 
VAL CA  HA   sing N N 450 
VAL C   O    doub N N 451 
VAL C   OXT  sing N N 452 
VAL CB  CG1  sing N N 453 
VAL CB  CG2  sing N N 454 
VAL CB  HB   sing N N 455 
VAL CG1 HG11 sing N N 456 
VAL CG1 HG12 sing N N 457 
VAL CG1 HG13 sing N N 458 
VAL CG2 HG21 sing N N 459 
VAL CG2 HG22 sing N N 460 
VAL CG2 HG23 sing N N 461 
VAL OXT HXT  sing N N 462 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6Y2E 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8R26 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021984 
_atom_sites.fract_transf_matrix[1][2]   -0.004413 
_atom_sites.fract_transf_matrix[1][3]   -0.003510 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014272 
_atom_sites.fract_transf_matrix[2][3]   -0.000648 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011832 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . SER A 1 1   ? -36.515 7.362   -21.786 1.00 29.11  ? 1   SER A N   1 
ATOM   2     C  CA  . SER A 1 1   ? -36.044 6.236   -20.982 1.00 35.59  ? 1   SER A CA  1 
ATOM   3     C  C   . SER A 1 1   ? -34.524 6.266   -20.829 1.00 26.83  ? 1   SER A C   1 
ATOM   4     O  O   . SER A 1 1   ? -33.809 6.629   -21.752 1.00 27.03  ? 1   SER A O   1 
ATOM   5     C  CB  . SER A 1 1   ? -36.505 4.915   -21.609 1.00 27.98  ? 1   SER A CB  1 
ATOM   6     O  OG  . SER A 1 1   ? -36.114 4.863   -22.973 1.00 34.72  ? 1   SER A OG  1 
ATOM   7     N  N   . GLY A 1 2   ? -34.047 5.849   -19.666 1.00 24.72  ? 2   GLY A N   1 
ATOM   8     C  CA  . GLY A 1 2   ? -32.641 6.034   -19.376 1.00 22.77  ? 2   GLY A CA  1 
ATOM   9     C  C   . GLY A 1 2   ? -32.382 7.408   -18.792 1.00 27.34  ? 2   GLY A C   1 
ATOM   10    O  O   . GLY A 1 2   ? -33.116 8.370   -19.033 1.00 27.80  ? 2   GLY A O   1 
ATOM   11    N  N   . PHE A 1 3   ? -31.308 7.503   -18.012 1.00 24.49  ? 3   PHE A N   1 
ATOM   12    C  CA  . PHE A 1 3   ? -30.916 8.761   -17.373 1.00 27.97  ? 3   PHE A CA  1 
ATOM   13    C  C   . PHE A 1 3   ? -29.404 8.782   -17.260 1.00 27.37  ? 3   PHE A C   1 
ATOM   14    O  O   . PHE A 1 3   ? -28.826 7.964   -16.531 1.00 27.68  ? 3   PHE A O   1 
ATOM   15    C  CB  . PHE A 1 3   ? -31.556 8.927   -15.993 1.00 25.29  ? 3   PHE A CB  1 
ATOM   16    C  CG  . PHE A 1 3   ? -31.520 10.335  -15.469 1.00 22.11  ? 3   PHE A CG  1 
ATOM   17    C  CD1 . PHE A 1 3   ? -32.440 11.281  -15.895 1.00 27.99  ? 3   PHE A CD1 1 
ATOM   18    C  CD2 . PHE A 1 3   ? -30.576 10.705  -14.531 1.00 23.07  ? 3   PHE A CD2 1 
ATOM   19    C  CE1 . PHE A 1 3   ? -32.406 12.574  -15.411 1.00 24.13  ? 3   PHE A CE1 1 
ATOM   20    C  CE2 . PHE A 1 3   ? -30.540 11.996  -14.036 1.00 28.64  ? 3   PHE A CE2 1 
ATOM   21    C  CZ  . PHE A 1 3   ? -31.458 12.932  -14.479 1.00 27.57  ? 3   PHE A CZ  1 
ATOM   22    N  N   . ARG A 1 4   ? -28.775 9.730   -17.953 1.00 25.12  ? 4   ARG A N   1 
ATOM   23    C  CA  . ARG A 1 4   ? -27.327 9.794   -18.034 1.00 25.12  ? 4   ARG A CA  1 
ATOM   24    C  C   . ARG A 1 4   ? -26.829 11.130  -17.513 1.00 24.53  ? 4   ARG A C   1 
ATOM   25    O  O   . ARG A 1 4   ? -27.580 12.099  -17.416 1.00 28.87  ? 4   ARG A O   1 
ATOM   26    C  CB  . ARG A 1 4   ? -26.832 9.574   -19.476 1.00 21.24  ? 4   ARG A CB  1 
ATOM   27    C  CG  . ARG A 1 4   ? -26.657 8.126   -19.859 1.00 26.01  ? 4   ARG A CG  1 
ATOM   28    C  CD  . ARG A 1 4   ? -25.249 7.643   -19.512 1.00 24.89  ? 4   ARG A CD  1 
ATOM   29    N  NE  . ARG A 1 4   ? -24.956 6.354   -20.129 1.00 34.53  ? 4   ARG A NE  1 
ATOM   30    C  CZ  . ARG A 1 4   ? -23.957 5.555   -19.768 1.00 39.15  ? 4   ARG A CZ  1 
ATOM   31    N  NH1 . ARG A 1 4   ? -23.100 5.899   -18.816 1.00 41.67  ? 4   ARG A NH1 1 
ATOM   32    N  NH2 . ARG A 1 4   ? -23.828 4.367   -20.355 1.00 27.20  ? 4   ARG A NH2 1 
ATOM   33    N  N   . LYS A 1 5   ? -25.573 11.143  -17.090 1.00 20.38  ? 5   LYS A N   1 
ATOM   34    C  CA  . LYS A 1 5   ? -24.880 12.401  -16.847 1.00 28.60  ? 5   LYS A CA  1 
ATOM   35    C  C   . LYS A 1 5   ? -24.618 13.061  -18.203 1.00 25.83  ? 5   LYS A C   1 
ATOM   36    O  O   . LYS A 1 5   ? -23.830 12.569  -19.022 1.00 22.70  ? 5   LYS A O   1 
ATOM   37    C  CB  . LYS A 1 5   ? -23.603 12.175  -16.038 1.00 23.19  ? 5   LYS A CB  1 
ATOM   38    C  CG  . LYS A 1 5   ? -22.920 13.465  -15.574 1.00 27.41  ? 5   LYS A CG  1 
ATOM   39    C  CD  . LYS A 1 5   ? -23.811 14.335  -14.671 1.00 23.09  ? 5   LYS A CD  1 
ATOM   40    C  CE  . LYS A 1 5   ? -23.913 13.790  -13.264 1.00 25.85  ? 5   LYS A CE  1 
ATOM   41    N  NZ  . LYS A 1 5   ? -22.639 13.856  -12.508 1.00 34.00  ? 5   LYS A NZ  1 
ATOM   42    N  N   . MET A 1 6   ? -25.349 14.126  -18.468 1.00 22.34  ? 6   MET A N   1 
ATOM   43    C  CA  . MET A 1 6   ? -25.456 14.700  -19.794 1.00 20.97  ? 6   MET A CA  1 
ATOM   44    C  C   . MET A 1 6   ? -24.883 16.102  -19.794 1.00 23.27  ? 6   MET A C   1 
ATOM   45    O  O   . MET A 1 6   ? -25.252 16.916  -18.947 1.00 22.09  ? 6   MET A O   1 
ATOM   46    C  CB  . MET A 1 6   ? -26.910 14.749  -20.213 1.00 22.26  ? 6   MET A CB  1 
ATOM   47    C  CG  . MET A 1 6   ? -27.090 14.871  -21.656 1.00 23.46  ? 6   MET A CG  1 
ATOM   48    S  SD  . MET A 1 6   ? -28.839 14.991  -21.941 1.00 39.68  ? 6   MET A SD  1 
ATOM   49    C  CE  . MET A 1 6   ? -29.204 13.332  -22.514 1.00 33.01  ? 6   MET A CE  1 
ATOM   50    N  N   . ALA A 1 7   ? -24.000 16.393  -20.743 1.00 24.22  ? 7   ALA A N   1 
ATOM   51    C  CA  . ALA A 1 7   ? -23.492 17.749  -20.909 1.00 21.89  ? 7   ALA A CA  1 
ATOM   52    C  C   . ALA A 1 7   ? -24.278 18.484  -21.995 1.00 21.78  ? 7   ALA A C   1 
ATOM   53    O  O   . ALA A 1 7   ? -24.817 17.870  -22.921 1.00 22.14  ? 7   ALA A O   1 
ATOM   54    C  CB  . ALA A 1 7   ? -22.003 17.736  -21.257 1.00 22.35  ? 7   ALA A CB  1 
ATOM   55    N  N   . PHE A 1 8   ? -24.314 19.814  -21.888 1.00 22.91  ? 8   PHE A N   1 
ATOM   56    C  CA  . PHE A 1 8   ? -24.848 20.641  -22.970 1.00 23.45  ? 8   PHE A CA  1 
ATOM   57    C  C   . PHE A 1 8   ? -24.040 20.412  -24.249 1.00 21.51  ? 8   PHE A C   1 
ATOM   58    O  O   . PHE A 1 8   ? -22.817 20.209  -24.200 1.00 21.21  ? 8   PHE A O   1 
ATOM   59    C  CB  . PHE A 1 8   ? -24.779 22.137  -22.621 1.00 25.09  ? 8   PHE A CB  1 
ATOM   60    C  CG  . PHE A 1 8   ? -25.761 22.581  -21.573 1.00 24.26  ? 8   PHE A CG  1 
ATOM   61    C  CD1 . PHE A 1 8   ? -27.095 22.777  -21.880 1.00 24.93  ? 8   PHE A CD1 1 
ATOM   62    C  CD2 . PHE A 1 8   ? -25.338 22.831  -20.284 1.00 24.51  ? 8   PHE A CD2 1 
ATOM   63    C  CE1 . PHE A 1 8   ? -28.005 23.188  -20.893 1.00 24.84  ? 8   PHE A CE1 1 
ATOM   64    C  CE2 . PHE A 1 8   ? -26.241 23.230  -19.301 1.00 23.44  ? 8   PHE A CE2 1 
ATOM   65    C  CZ  . PHE A 1 8   ? -27.577 23.410  -19.612 1.00 21.93  ? 8   PHE A CZ  1 
ATOM   66    N  N   . PRO A 1 9   ? -24.686 20.475  -25.411 1.00 22.84  ? 9   PRO A N   1 
ATOM   67    C  CA  . PRO A 1 9   ? -23.927 20.455  -26.669 1.00 21.31  ? 9   PRO A CA  1 
ATOM   68    C  C   . PRO A 1 9   ? -22.946 21.623  -26.692 1.00 21.40  ? 9   PRO A C   1 
ATOM   69    O  O   . PRO A 1 9   ? -23.270 22.732  -26.278 1.00 15.99  ? 9   PRO A O   1 
ATOM   70    C  CB  . PRO A 1 9   ? -25.008 20.592  -27.745 1.00 22.17  ? 9   PRO A CB  1 
ATOM   71    C  CG  . PRO A 1 9   ? -26.166 21.248  -27.042 1.00 25.23  ? 9   PRO A CG  1 
ATOM   72    C  CD  . PRO A 1 9   ? -26.112 20.798  -25.614 1.00 24.46  ? 9   PRO A CD  1 
ATOM   73    N  N   . SER A 1 10  ? -21.731 21.356  -27.161 1.00 23.30  ? 10  SER A N   1 
ATOM   74    C  CA  . SER A 1 10  ? -20.621 22.260  -26.940 1.00 22.85  ? 10  SER A CA  1 
ATOM   75    C  C   . SER A 1 10  ? -20.274 23.112  -28.152 1.00 21.68  ? 10  SER A C   1 
ATOM   76    O  O   . SER A 1 10  ? -19.295 23.854  -28.088 1.00 22.98  ? 10  SER A O   1 
ATOM   77    C  CB  . SER A 1 10  ? -19.385 21.475  -26.499 1.00 23.81  ? 10  SER A CB  1 
ATOM   78    O  OG  . SER A 1 10  ? -18.941 20.615  -27.534 1.00 26.20  ? 10  SER A OG  1 
ATOM   79    N  N   . GLY A 1 11  ? -21.048 23.028  -29.239 1.00 23.69  ? 11  GLY A N   1 
ATOM   80    C  CA  . GLY A 1 11  ? -20.685 23.720  -30.475 1.00 24.65  ? 11  GLY A CA  1 
ATOM   81    C  C   . GLY A 1 11  ? -20.497 25.222  -30.315 1.00 25.52  ? 11  GLY A C   1 
ATOM   82    O  O   . GLY A 1 11  ? -19.522 25.797  -30.804 1.00 25.10  ? 11  GLY A O   1 
ATOM   83    N  N   . LYS A 1 12  ? -21.461 25.884  -29.675 1.00 25.83  ? 12  LYS A N   1 
ATOM   84    C  CA  . LYS A 1 12  ? -21.383 27.328  -29.483 1.00 25.03  ? 12  LYS A CA  1 
ATOM   85    C  C   . LYS A 1 12  ? -20.093 27.744  -28.782 1.00 26.16  ? 12  LYS A C   1 
ATOM   86    O  O   . LYS A 1 12  ? -19.560 28.829  -29.042 1.00 26.54  ? 12  LYS A O   1 
ATOM   87    C  CB  . LYS A 1 12  ? -22.584 27.799  -28.666 1.00 24.02  ? 12  LYS A CB  1 
ATOM   88    C  CG  . LYS A 1 12  ? -23.933 27.625  -29.324 1.00 24.01  ? 12  LYS A CG  1 
ATOM   89    C  CD  . LYS A 1 12  ? -25.004 28.247  -28.443 1.00 28.62  ? 12  LYS A CD  1 
ATOM   90    C  CE  . LYS A 1 12  ? -26.399 27.911  -28.921 1.00 33.12  ? 12  LYS A CE  1 
ATOM   91    N  NZ  . LYS A 1 12  ? -26.676 28.463  -30.260 1.00 40.17  ? 12  LYS A NZ  1 
ATOM   92    N  N   . VAL A 1 13  ? -19.572 26.896  -27.901 1.00 24.11  ? 13  VAL A N   1 
ATOM   93    C  CA  . VAL A 1 13  ? -18.392 27.225  -27.116 1.00 20.72  ? 13  VAL A CA  1 
ATOM   94    C  C   . VAL A 1 13  ? -17.116 26.889  -27.871 1.00 26.13  ? 13  VAL A C   1 
ATOM   95    O  O   . VAL A 1 13  ? -16.126 27.622  -27.779 1.00 26.43  ? 13  VAL A O   1 
ATOM   96    C  CB  . VAL A 1 13  ? -18.477 26.474  -25.774 1.00 23.79  ? 13  VAL A CB  1 
ATOM   97    C  CG1 . VAL A 1 13  ? -17.274 26.779  -24.896 1.00 20.93  ? 13  VAL A CG1 1 
ATOM   98    C  CG2 . VAL A 1 13  ? -19.803 26.786  -25.074 1.00 20.56  ? 13  VAL A CG2 1 
ATOM   99    N  N   . GLU A 1 14  ? -17.144 25.798  -28.646 1.00 22.91  ? 14  GLU A N   1 
ATOM   100   C  CA  . GLU A 1 14  ? -15.985 25.398  -29.440 1.00 23.89  ? 14  GLU A CA  1 
ATOM   101   C  C   . GLU A 1 14  ? -15.504 26.536  -30.336 1.00 22.02  ? 14  GLU A C   1 
ATOM   102   O  O   . GLU A 1 14  ? -14.301 26.795  -30.426 1.00 22.03  ? 14  GLU A O   1 
ATOM   103   C  CB  . GLU A 1 14  ? -16.335 24.159  -30.283 1.00 21.15  ? 14  GLU A CB  1 
ATOM   104   C  CG  . GLU A 1 14  ? -16.623 22.892  -29.474 1.00 24.23  ? 14  GLU A CG  1 
ATOM   105   C  CD  . GLU A 1 14  ? -17.240 21.750  -30.302 1.00 24.76  ? 14  GLU A CD  1 
ATOM   106   O  OE1 . GLU A 1 14  ? -16.751 21.404  -31.408 1.00 22.93  ? 14  GLU A OE1 1 
ATOM   107   O  OE2 . GLU A 1 14  ? -18.232 21.178  -29.811 1.00 27.26  ? 14  GLU A OE2 1 
ATOM   108   N  N   . GLY A 1 15  ? -16.429 27.243  -30.984 1.00 20.62  ? 15  GLY A N   1 
ATOM   109   C  CA  . GLY A 1 15  ? -16.048 28.338  -31.846 1.00 23.12  ? 15  GLY A CA  1 
ATOM   110   C  C   . GLY A 1 15  ? -15.407 29.511  -31.130 1.00 25.42  ? 15  GLY A C   1 
ATOM   111   O  O   . GLY A 1 15  ? -14.945 30.438  -31.805 1.00 26.79  ? 15  GLY A O   1 
ATOM   112   N  N   . CYS A 1 16  ? -15.344 29.481  -29.794 1.00 22.89  ? 16  CYS A N   1 
ATOM   113   C  CA  . CYS A 1 16  ? -14.762 30.563  -29.010 1.00 21.54  ? 16  CYS A CA  1 
ATOM   114   C  C   . CYS A 1 16  ? -13.394 30.250  -28.422 1.00 23.73  ? 16  CYS A C   1 
ATOM   115   O  O   . CYS A 1 16  ? -12.786 31.145  -27.825 1.00 22.07  ? 16  CYS A O   1 
ATOM   116   C  CB  . CYS A 1 16  ? -15.710 30.961  -27.879 1.00 18.97  ? 16  CYS A CB  1 
ATOM   117   S  SG  . CYS A 1 16  ? -17.296 31.526  -28.479 1.00 25.83  ? 16  CYS A SG  1 
ATOM   118   N  N   . MET A 1 17  ? -12.883 29.032  -28.576 1.00 19.71  ? 17  MET A N   1 
ATOM   119   C  CA  . MET A 1 17  ? -11.635 28.651  -27.931 1.00 21.15  ? 17  MET A CA  1 
ATOM   120   C  C   . MET A 1 17  ? -10.453 29.026  -28.822 1.00 23.71  ? 17  MET A C   1 
ATOM   121   O  O   . MET A 1 17  ? -10.476 28.778  -30.035 1.00 23.76  ? 17  MET A O   1 
ATOM   122   C  CB  . MET A 1 17  ? -11.617 27.154  -27.602 1.00 20.06  ? 17  MET A CB  1 
ATOM   123   C  CG  . MET A 1 17  ? -12.743 26.738  -26.661 1.00 18.25  ? 17  MET A CG  1 
ATOM   124   S  SD  . MET A 1 17  ? -12.925 27.741  -25.157 1.00 22.26  ? 17  MET A SD  1 
ATOM   125   C  CE  . MET A 1 17  ? -11.292 27.588  -24.450 1.00 21.49  ? 17  MET A CE  1 
ATOM   126   N  N   . VAL A 1 18  ? -9.443  29.667  -28.225 1.00 20.21  ? 18  VAL A N   1 
ATOM   127   C  CA  . VAL A 1 18  ? -8.224  30.049  -28.923 1.00 22.18  ? 18  VAL A CA  1 
ATOM   128   C  C   . VAL A 1 18  ? -7.028  29.657  -28.066 1.00 18.22  ? 18  VAL A C   1 
ATOM   129   O  O   . VAL A 1 18  ? -7.160  29.244  -26.917 1.00 20.52  ? 18  VAL A O   1 
ATOM   130   C  CB  . VAL A 1 18  ? -8.180  31.557  -29.247 1.00 17.51  ? 18  VAL A CB  1 
ATOM   131   C  CG1 . VAL A 1 18  ? -9.366  31.933  -30.081 1.00 18.36  ? 18  VAL A CG1 1 
ATOM   132   C  CG2 . VAL A 1 18  ? -8.147  32.368  -27.971 1.00 16.29  ? 18  VAL A CG2 1 
ATOM   133   N  N   . GLN A 1 19  ? -5.848  29.830  -28.636 1.00 22.75  ? 19  GLN A N   1 
ATOM   134   C  CA  . GLN A 1 19  ? -4.597  29.485  -27.985 1.00 25.45  ? 19  GLN A CA  1 
ATOM   135   C  C   . GLN A 1 19  ? -3.825  30.760  -27.688 1.00 22.57  ? 19  GLN A C   1 
ATOM   136   O  O   . GLN A 1 19  ? -3.566  31.548  -28.597 1.00 26.44  ? 19  GLN A O   1 
ATOM   137   C  CB  . GLN A 1 19  ? -3.780  28.554  -28.873 1.00 24.97  ? 19  GLN A CB  1 
ATOM   138   C  CG  . GLN A 1 19  ? -2.351  28.415  -28.442 1.00 29.13  ? 19  GLN A CG  1 
ATOM   139   C  CD  . GLN A 1 19  ? -1.675  27.228  -29.078 1.00 35.77  ? 19  GLN A CD  1 
ATOM   140   O  OE1 . GLN A 1 19  ? -0.582  26.839  -28.671 1.00 45.16  ? 19  GLN A OE1 1 
ATOM   141   N  NE2 . GLN A 1 19  ? -2.340  26.607  -30.053 1.00 38.19  ? 19  GLN A NE2 1 
ATOM   142   N  N   . VAL A 1 20  ? -3.461  30.958  -26.428 1.00 23.50  ? 20  VAL A N   1 
ATOM   143   C  CA  . VAL A 1 20  ? -2.733  32.141  -25.981 1.00 26.58  ? 20  VAL A CA  1 
ATOM   144   C  C   . VAL A 1 20  ? -1.377  31.703  -25.446 1.00 27.82  ? 20  VAL A C   1 
ATOM   145   O  O   . VAL A 1 20  ? -1.306  30.827  -24.574 1.00 25.53  ? 20  VAL A O   1 
ATOM   146   C  CB  . VAL A 1 20  ? -3.514  32.918  -24.908 1.00 25.96  ? 20  VAL A CB  1 
ATOM   147   C  CG1 . VAL A 1 20  ? -2.725  34.137  -24.476 1.00 23.15  ? 20  VAL A CG1 1 
ATOM   148   C  CG2 . VAL A 1 20  ? -4.864  33.323  -25.449 1.00 26.49  ? 20  VAL A CG2 1 
ATOM   149   N  N   . THR A 1 21  ? -0.310  32.307  -25.973 1.00 27.54  ? 21  THR A N   1 
ATOM   150   C  CA  . THR A 1 21  ? 1.061   32.004  -25.578 1.00 29.22  ? 21  THR A CA  1 
ATOM   151   C  C   . THR A 1 21  ? 1.779   33.264  -25.126 1.00 27.48  ? 21  THR A C   1 
ATOM   152   O  O   . THR A 1 21  ? 1.585   34.339  -25.691 1.00 30.28  ? 21  THR A O   1 
ATOM   153   C  CB  . THR A 1 21  ? 1.838   31.354  -26.725 1.00 26.77  ? 21  THR A CB  1 
ATOM   154   O  OG1 . THR A 1 21  ? 1.172   30.140  -27.089 1.00 34.74  ? 21  THR A OG1 1 
ATOM   155   C  CG2 . THR A 1 21  ? 3.269   31.038  -26.306 1.00 26.47  ? 21  THR A CG2 1 
ATOM   156   N  N   . CYS A 1 22  ? 2.597   33.131  -24.091 1.00 29.39  ? 22  CYS A N   1 
ATOM   157   C  CA  . CYS A 1 22  ? 3.427   34.242  -23.653 1.00 33.80  ? 22  CYS A CA  1 
ATOM   158   C  C   . CYS A 1 22  ? 4.738   33.627  -23.161 1.00 35.36  ? 22  CYS A C   1 
ATOM   159   O  O   . CYS A 1 22  ? 4.779   33.010  -22.088 1.00 27.41  ? 22  CYS A O   1 
ATOM   160   C  CB  . CYS A 1 22  ? 2.718   35.055  -22.584 1.00 33.00  ? 22  CYS A CB  1 
ATOM   161   S  SG  . CYS A 1 22  ? 3.433   36.659  -22.344 1.00 40.51  ? 22  CYS A SG  1 
ATOM   162   N  N   . GLY A 1 23  ? 5.788   33.760  -23.977 1.00 35.08  ? 23  GLY A N   1 
ATOM   163   C  CA  . GLY A 1 23  ? 7.048   33.086  -23.720 1.00 34.94  ? 23  GLY A CA  1 
ATOM   164   C  C   . GLY A 1 23  ? 6.961   31.590  -23.954 1.00 35.58  ? 23  GLY A C   1 
ATOM   165   O  O   . GLY A 1 23  ? 6.671   31.131  -25.065 1.00 37.62  ? 23  GLY A O   1 
ATOM   166   N  N   . THR A 1 24  ? 7.233   30.814  -22.907 1.00 41.27  ? 24  THR A N   1 
ATOM   167   C  CA  . THR A 1 24  ? 7.143   29.361  -22.960 1.00 36.15  ? 24  THR A CA  1 
ATOM   168   C  C   . THR A 1 24  ? 5.844   28.842  -22.363 1.00 32.10  ? 24  THR A C   1 
ATOM   169   O  O   . THR A 1 24  ? 5.663   27.627  -22.262 1.00 36.19  ? 24  THR A O   1 
ATOM   170   C  CB  . THR A 1 24  ? 8.345   28.732  -22.247 1.00 41.17  ? 24  THR A CB  1 
ATOM   171   O  OG1 . THR A 1 24  ? 8.568   29.385  -20.986 1.00 40.62  ? 24  THR A OG1 1 
ATOM   172   C  CG2 . THR A 1 24  ? 9.597   28.823  -23.108 1.00 37.79  ? 24  THR A CG2 1 
ATOM   173   N  N   . THR A 1 25  ? 4.923   29.734  -22.002 1.00 34.14  ? 25  THR A N   1 
ATOM   174   C  CA  . THR A 1 25  ? 3.650   29.347  -21.418 1.00 29.79  ? 25  THR A CA  1 
ATOM   175   C  C   . THR A 1 25  ? 2.542   29.444  -22.454 1.00 26.08  ? 25  THR A C   1 
ATOM   176   O  O   . THR A 1 25  ? 2.340   30.492  -23.068 1.00 31.01  ? 25  THR A O   1 
ATOM   177   C  CB  . THR A 1 25  ? 3.301   30.234  -20.232 1.00 29.74  ? 25  THR A CB  1 
ATOM   178   O  OG1 . THR A 1 25  ? 4.460   30.380  -19.411 1.00 29.62  ? 25  THR A OG1 1 
ATOM   179   C  CG2 . THR A 1 25  ? 2.181   29.572  -19.413 1.00 22.55  ? 25  THR A CG2 1 
ATOM   180   N  N   . THR A 1 26  ? 1.800   28.368  -22.609 1.00 27.08  ? 26  THR A N   1 
ATOM   181   C  CA  . THR A 1 26  ? 0.685   28.345  -23.531 1.00 27.71  ? 26  THR A CA  1 
ATOM   182   C  C   . THR A 1 26  ? -0.515  27.865  -22.741 1.00 26.69  ? 26  THR A C   1 
ATOM   183   O  O   . THR A 1 26  ? -0.406  26.895  -21.975 1.00 21.46  ? 26  THR A O   1 
ATOM   184   C  CB  . THR A 1 26  ? 0.953   27.417  -24.719 1.00 26.68  ? 26  THR A CB  1 
ATOM   185   O  OG1 . THR A 1 26  ? 2.086   27.894  -25.448 1.00 34.88  ? 26  THR A OG1 1 
ATOM   186   C  CG2 . THR A 1 26  ? -0.221  27.439  -25.659 1.00 29.64  ? 26  THR A CG2 1 
ATOM   187   N  N   . LEU A 1 27  ? -1.648  28.544  -22.909 1.00 26.22  ? 27  LEU A N   1 
ATOM   188   C  CA  . LEU A 1 27  ? -2.887  28.038  -22.340 1.00 22.02  ? 27  LEU A CA  1 
ATOM   189   C  C   . LEU A 1 27  ? -4.018  28.494  -23.247 1.00 24.59  ? 27  LEU A C   1 
ATOM   190   O  O   . LEU A 1 27  ? -3.781  29.053  -24.322 1.00 21.85  ? 27  LEU A O   1 
ATOM   191   C  CB  . LEU A 1 27  ? -3.044  28.482  -20.874 1.00 22.62  ? 27  LEU A CB  1 
ATOM   192   C  CG  . LEU A 1 27  ? -2.797  29.944  -20.475 1.00 27.17  ? 27  LEU A CG  1 
ATOM   193   C  CD1 . LEU A 1 27  ? -3.881  30.885  -21.049 1.00 24.50  ? 27  LEU A CD1 1 
ATOM   194   C  CD2 . LEU A 1 27  ? -2.672  30.132  -18.966 1.00 22.94  ? 27  LEU A CD2 1 
ATOM   195   N  N   . ASN A 1 28  ? -5.249  28.281  -22.796 1.00 22.23  ? 28  ASN A N   1 
ATOM   196   C  CA  . ASN A 1 28  ? -6.436  28.510  -23.599 1.00 20.38  ? 28  ASN A CA  1 
ATOM   197   C  C   . ASN A 1 28  ? -7.027  29.878  -23.296 1.00 21.97  ? 28  ASN A C   1 
ATOM   198   O  O   . ASN A 1 28  ? -6.883  30.408  -22.197 1.00 20.97  ? 28  ASN A O   1 
ATOM   199   C  CB  . ASN A 1 28  ? -7.488  27.430  -23.326 1.00 25.46  ? 28  ASN A CB  1 
ATOM   200   C  CG  . ASN A 1 28  ? -6.960  26.019  -23.555 1.00 25.55  ? 28  ASN A CG  1 
ATOM   201   O  OD1 . ASN A 1 28  ? -6.845  25.575  -24.702 1.00 27.46  ? 28  ASN A OD1 1 
ATOM   202   N  ND2 . ASN A 1 28  ? -6.634  25.313  -22.476 1.00 23.19  ? 28  ASN A ND2 1 
ATOM   203   N  N   . GLY A 1 29  ? -7.688  30.455  -24.294 1.00 21.21  ? 29  GLY A N   1 
ATOM   204   C  CA  . GLY A 1 29  ? -8.409  31.687  -24.103 1.00 17.58  ? 29  GLY A CA  1 
ATOM   205   C  C   . GLY A 1 29  ? -9.800  31.574  -24.689 1.00 14.23  ? 29  GLY A C   1 
ATOM   206   O  O   . GLY A 1 29  ? -10.098 30.677  -25.492 1.00 18.48  ? 29  GLY A O   1 
ATOM   207   N  N   . LEU A 1 30  ? -10.649 32.496  -24.266 1.00 13.60  ? 30  LEU A N   1 
ATOM   208   C  CA  . LEU A 1 30  ? -12.037 32.592  -24.707 1.00 16.13  ? 30  LEU A CA  1 
ATOM   209   C  C   . LEU A 1 30  ? -12.212 33.865  -25.519 1.00 16.01  ? 30  LEU A C   1 
ATOM   210   O  O   . LEU A 1 30  ? -12.054 34.971  -24.990 1.00 15.12  ? 30  LEU A O   1 
ATOM   211   C  CB  . LEU A 1 30  ? -12.999 32.614  -23.522 1.00 16.39  ? 30  LEU A CB  1 
ATOM   212   C  CG  . LEU A 1 30  ? -14.459 32.603  -23.930 1.00 14.34  ? 30  LEU A CG  1 
ATOM   213   C  CD1 . LEU A 1 30  ? -14.796 31.236  -24.428 1.00 22.68  ? 30  LEU A CD1 1 
ATOM   214   C  CD2 . LEU A 1 30  ? -15.280 32.968  -22.727 1.00 15.19  ? 30  LEU A CD2 1 
ATOM   215   N  N   . TRP A 1 31  ? -12.553 33.695  -26.789 1.00 20.24  ? 31  TRP A N   1 
ATOM   216   C  CA  . TRP A 1 31  ? -12.633 34.780  -27.765 1.00 20.40  ? 31  TRP A CA  1 
ATOM   217   C  C   . TRP A 1 31  ? -14.095 35.134  -27.998 1.00 21.54  ? 31  TRP A C   1 
ATOM   218   O  O   . TRP A 1 31  ? -14.811 34.384  -28.671 1.00 23.39  ? 31  TRP A O   1 
ATOM   219   C  CB  . TRP A 1 31  ? -11.965 34.351  -29.071 1.00 18.60  ? 31  TRP A CB  1 
ATOM   220   C  CG  . TRP A 1 31  ? -11.887 35.420  -30.118 1.00 26.12  ? 31  TRP A CG  1 
ATOM   221   C  CD1 . TRP A 1 31  ? -12.011 36.785  -29.936 1.00 20.58  ? 31  TRP A CD1 1 
ATOM   222   C  CD2 . TRP A 1 31  ? -11.662 35.220  -31.520 1.00 23.20  ? 31  TRP A CD2 1 
ATOM   223   N  NE1 . TRP A 1 31  ? -11.867 37.433  -31.141 1.00 22.49  ? 31  TRP A NE1 1 
ATOM   224   C  CE2 . TRP A 1 31  ? -11.654 36.497  -32.128 1.00 23.24  ? 31  TRP A CE2 1 
ATOM   225   C  CE3 . TRP A 1 31  ? -11.455 34.085  -32.317 1.00 22.06  ? 31  TRP A CE3 1 
ATOM   226   C  CZ2 . TRP A 1 31  ? -11.463 36.667  -33.498 1.00 20.65  ? 31  TRP A CZ2 1 
ATOM   227   C  CZ3 . TRP A 1 31  ? -11.262 34.250  -33.668 1.00 24.29  ? 31  TRP A CZ3 1 
ATOM   228   C  CH2 . TRP A 1 31  ? -11.269 35.540  -34.253 1.00 24.96  ? 31  TRP A CH2 1 
ATOM   229   N  N   . LEU A 1 32  ? -14.531 36.279  -27.471 1.00 16.11  ? 32  LEU A N   1 
ATOM   230   C  CA  . LEU A 1 32  ? -15.895 36.767  -27.653 1.00 18.04  ? 32  LEU A CA  1 
ATOM   231   C  C   . LEU A 1 32  ? -15.841 38.206  -28.159 1.00 26.87  ? 32  LEU A C   1 
ATOM   232   O  O   . LEU A 1 32  ? -15.233 39.074  -27.515 1.00 29.00  ? 32  LEU A O   1 
ATOM   233   C  CB  . LEU A 1 32  ? -16.690 36.685  -26.350 1.00 19.27  ? 32  LEU A CB  1 
ATOM   234   C  CG  . LEU A 1 32  ? -16.846 35.321  -25.632 1.00 22.51  ? 32  LEU A CG  1 
ATOM   235   C  CD1 . LEU A 1 32  ? -17.236 35.525  -24.174 1.00 15.83  ? 32  LEU A CD1 1 
ATOM   236   C  CD2 . LEU A 1 32  ? -17.868 34.392  -26.329 1.00 16.83  ? 32  LEU A CD2 1 
ATOM   237   N  N   . ASP A 1 33  ? -16.493 38.455  -29.295 1.00 23.88  ? 33  ASP A N   1 
ATOM   238   C  CA  . ASP A 1 33  ? -16.427 39.728  -30.027 1.00 25.39  ? 33  ASP A CA  1 
ATOM   239   C  C   . ASP A 1 33  ? -14.942 40.003  -30.295 1.00 23.66  ? 33  ASP A C   1 
ATOM   240   O  O   . ASP A 1 33  ? -14.242 39.144  -30.853 1.00 23.77  ? 33  ASP A O   1 
ATOM   241   C  CB  . ASP A 1 33  ? -17.205 40.813  -29.278 1.00 28.57  ? 33  ASP A CB  1 
ATOM   242   C  CG  . ASP A 1 33  ? -18.666 40.394  -28.990 1.00 34.99  ? 33  ASP A CG  1 
ATOM   243   O  OD1 . ASP A 1 33  ? -19.319 39.808  -29.884 1.00 33.23  ? 33  ASP A OD1 1 
ATOM   244   O  OD2 . ASP A 1 33  ? -19.178 40.655  -27.878 1.00 40.51  ? 33  ASP A OD2 1 
ATOM   245   N  N   . ASP A 1 34  ? -14.409 41.153  -29.920 1.00 19.00  ? 34  ASP A N   1 
ATOM   246   C  CA  . ASP A 1 34  ? -13.017 41.465  -30.227 1.00 22.57  ? 34  ASP A CA  1 
ATOM   247   C  C   . ASP A 1 34  ? -12.112 41.384  -28.999 1.00 23.16  ? 34  ASP A C   1 
ATOM   248   O  O   . ASP A 1 34  ? -11.096 42.079  -28.932 1.00 23.96  ? 34  ASP A O   1 
ATOM   249   C  CB  . ASP A 1 34  ? -12.937 42.845  -30.866 1.00 22.79  ? 34  ASP A CB  1 
ATOM   250   C  CG  . ASP A 1 34  ? -13.500 43.915  -29.959 1.00 26.78  ? 34  ASP A CG  1 
ATOM   251   O  OD1 . ASP A 1 34  ? -14.403 43.579  -29.166 1.00 26.12  ? 34  ASP A OD1 1 
ATOM   252   O  OD2 . ASP A 1 34  ? -13.021 45.067  -30.009 1.00 36.13  ? 34  ASP A OD2 1 
ATOM   253   N  N   . VAL A 1 35  ? -12.463 40.534  -28.020 1.00 24.32  ? 35  VAL A N   1 
ATOM   254   C  CA  . VAL A 1 35  ? -11.702 40.383  -26.782 1.00 22.66  ? 35  VAL A CA  1 
ATOM   255   C  C   . VAL A 1 35  ? -11.405 38.911  -26.537 1.00 23.62  ? 35  VAL A C   1 
ATOM   256   O  O   . VAL A 1 35  ? -12.279 38.056  -26.719 1.00 24.70  ? 35  VAL A O   1 
ATOM   257   C  CB  . VAL A 1 35  ? -12.470 40.966  -25.578 1.00 22.29  ? 35  VAL A CB  1 
ATOM   258   C  CG1 . VAL A 1 35  ? -11.674 40.770  -24.329 1.00 18.83  ? 35  VAL A CG1 1 
ATOM   259   C  CG2 . VAL A 1 35  ? -12.820 42.427  -25.806 1.00 19.61  ? 35  VAL A CG2 1 
ATOM   260   N  N   . VAL A 1 36  ? -10.186 38.614  -26.094 1.00 22.56  ? 36  VAL A N   1 
ATOM   261   C  CA  . VAL A 1 36  ? -9.794  37.273  -25.666 1.00 19.44  ? 36  VAL A CA  1 
ATOM   262   C  C   . VAL A 1 36  ? -9.581  37.302  -24.159 1.00 20.32  ? 36  VAL A C   1 
ATOM   263   O  O   . VAL A 1 36  ? -8.864  38.173  -23.653 1.00 18.35  ? 36  VAL A O   1 
ATOM   264   C  CB  . VAL A 1 36  ? -8.525  36.794  -26.395 1.00 18.89  ? 36  VAL A CB  1 
ATOM   265   C  CG1 . VAL A 1 36  ? -7.950  35.543  -25.741 1.00 16.18  ? 36  VAL A CG1 1 
ATOM   266   C  CG2 . VAL A 1 36  ? -8.824  36.538  -27.856 1.00 15.41  ? 36  VAL A CG2 1 
ATOM   267   N  N   . TYR A 1 37  ? -10.271 36.407  -23.437 1.00 19.93  ? 37  TYR A N   1 
ATOM   268   C  CA  . TYR A 1 37  ? -10.134 36.245  -21.994 1.00 17.07  ? 37  TYR A CA  1 
ATOM   269   C  C   . TYR A 1 37  ? -9.367  34.968  -21.696 1.00 16.49  ? 37  TYR A C   1 
ATOM   270   O  O   . TYR A 1 37  ? -9.641  33.930  -22.300 1.00 18.05  ? 37  TYR A O   1 
ATOM   271   C  CB  . TYR A 1 37  ? -11.495 36.172  -21.309 1.00 20.40  ? 37  TYR A CB  1 
ATOM   272   C  CG  . TYR A 1 37  ? -12.472 37.279  -21.685 1.00 24.21  ? 37  TYR A CG  1 
ATOM   273   C  CD1 . TYR A 1 37  ? -13.136 37.248  -22.915 1.00 18.68  ? 37  TYR A CD1 1 
ATOM   274   C  CD2 . TYR A 1 37  ? -12.773 38.315  -20.799 1.00 19.02  ? 37  TYR A CD2 1 
ATOM   275   C  CE1 . TYR A 1 37  ? -14.032 38.232  -23.263 1.00 20.34  ? 37  TYR A CE1 1 
ATOM   276   C  CE2 . TYR A 1 37  ? -13.690 39.300  -21.142 1.00 17.66  ? 37  TYR A CE2 1 
ATOM   277   C  CZ  . TYR A 1 37  ? -14.311 39.257  -22.375 1.00 18.75  ? 37  TYR A CZ  1 
ATOM   278   O  OH  . TYR A 1 37  ? -15.228 40.224  -22.751 1.00 20.46  ? 37  TYR A OH  1 
ATOM   279   N  N   . CYS A 1 38  ? -8.415  35.046  -20.771 1.00 17.80  ? 38  CYS A N   1 
ATOM   280   C  CA  . CYS A 1 38  ? -7.602  33.907  -20.362 1.00 16.95  ? 38  CYS A CA  1 
ATOM   281   C  C   . CYS A 1 38  ? -7.061  34.187  -18.972 1.00 20.78  ? 38  CYS A C   1 
ATOM   282   O  O   . CYS A 1 38  ? -7.065  35.343  -18.528 1.00 23.57  ? 38  CYS A O   1 
ATOM   283   C  CB  . CYS A 1 38  ? -6.445  33.657  -21.341 1.00 19.33  ? 38  CYS A CB  1 
ATOM   284   S  SG  . CYS A 1 38  ? -5.134  34.914  -21.308 1.00 20.98  ? 38  CYS A SG  1 
ATOM   285   N  N   . PRO A 1 39  ? -6.554  33.164  -18.272 1.00 22.20  ? 39  PRO A N   1 
ATOM   286   C  CA  . PRO A 1 39  ? -5.987  33.408  -16.948 1.00 20.24  ? 39  PRO A CA  1 
ATOM   287   C  C   . PRO A 1 39  ? -4.766  34.296  -17.041 1.00 18.34  ? 39  PRO A C   1 
ATOM   288   O  O   . PRO A 1 39  ? -3.921  34.135  -17.916 1.00 19.24  ? 39  PRO A O   1 
ATOM   289   C  CB  . PRO A 1 39  ? -5.626  32.002  -16.435 1.00 20.15  ? 39  PRO A CB  1 
ATOM   290   C  CG  . PRO A 1 39  ? -6.475  31.070  -17.225 1.00 21.91  ? 39  PRO A CG  1 
ATOM   291   C  CD  . PRO A 1 39  ? -6.605  31.718  -18.583 1.00 23.58  ? 39  PRO A CD  1 
ATOM   292   N  N   . ARG A 1 40  ? -4.662  35.226  -16.101 1.00 19.32  ? 40  ARG A N   1 
ATOM   293   C  CA  . ARG A 1 40  ? -3.561  36.175  -16.160 1.00 21.01  ? 40  ARG A CA  1 
ATOM   294   C  C   . ARG A 1 40  ? -2.196  35.499  -16.015 1.00 23.96  ? 40  ARG A C   1 
ATOM   295   O  O   . ARG A 1 40  ? -1.193  36.028  -16.523 1.00 23.13  ? 40  ARG A O   1 
ATOM   296   C  CB  . ARG A 1 40  ? -3.757  37.247  -15.098 1.00 18.76  ? 40  ARG A CB  1 
ATOM   297   C  CG  . ARG A 1 40  ? -3.597  36.767  -13.664 1.00 20.31  ? 40  ARG A CG  1 
ATOM   298   C  CD  . ARG A 1 40  ? -3.775  37.958  -12.715 1.00 20.84  ? 40  ARG A CD  1 
ATOM   299   N  NE  . ARG A 1 40  ? -3.753  37.577  -11.309 1.00 21.50  ? 40  ARG A NE  1 
ATOM   300   C  CZ  . ARG A 1 40  ? -3.793  38.444  -10.300 1.00 23.40  ? 40  ARG A CZ  1 
ATOM   301   N  NH1 . ARG A 1 40  ? -3.806  39.754  -10.506 1.00 18.13  ? 40  ARG A NH1 1 
ATOM   302   N  NH2 . ARG A 1 40  ? -3.839  37.987  -9.057  1.00 19.66  ? 40  ARG A NH2 1 
ATOM   303   N  N   . HIS A 1 41  ? -2.128  34.316  -15.354 1.00 20.23  ? 41  HIS A N   1 
ATOM   304   C  CA  . HIS A 1 41  ? -0.814  33.687  -15.142 1.00 20.88  ? 41  HIS A CA  1 
ATOM   305   C  C   . HIS A 1 41  ? -0.223  33.094  -16.406 1.00 22.87  ? 41  HIS A C   1 
ATOM   306   O  O   . HIS A 1 41  ? 0.790   32.386  -16.351 1.00 25.12  ? 41  HIS A O   1 
ATOM   307   C  CB  . HIS A 1 41  ? -0.857  32.626  -14.028 1.00 20.14  ? 41  HIS A CB  1 
ATOM   308   C  CG  . HIS A 1 41  ? -1.681  31.417  -14.349 1.00 20.38  ? 41  HIS A CG  1 
ATOM   309   N  ND1 . HIS A 1 41  ? -2.964  31.240  -13.870 1.00 24.92  ? 41  HIS A ND1 1 
ATOM   310   C  CD2 . HIS A 1 41  ? -1.395  30.305  -15.069 1.00 18.15  ? 41  HIS A CD2 1 
ATOM   311   C  CE1 . HIS A 1 41  ? -3.442  30.082  -14.293 1.00 18.44  ? 41  HIS A CE1 1 
ATOM   312   N  NE2 . HIS A 1 41  ? -2.509  29.492  -15.022 1.00 23.02  ? 41  HIS A NE2 1 
ATOM   313   N  N   . VAL A 1 42  ? -0.822  33.362  -17.567 1.00 25.75  ? 42  VAL A N   1 
ATOM   314   C  CA  . VAL A 1 42  ? -0.134  33.124  -18.823 1.00 27.32  ? 42  VAL A CA  1 
ATOM   315   C  C   . VAL A 1 42  ? 1.149   33.951  -18.897 1.00 26.84  ? 42  VAL A C   1 
ATOM   316   O  O   . VAL A 1 42  ? 2.063   33.606  -19.658 1.00 29.09  ? 42  VAL A O   1 
ATOM   317   C  CB  . VAL A 1 42  ? -1.081  33.419  -20.009 1.00 24.57  ? 42  VAL A CB  1 
ATOM   318   C  CG1 . VAL A 1 42  ? -1.305  34.936  -20.172 1.00 22.18  ? 42  VAL A CG1 1 
ATOM   319   C  CG2 . VAL A 1 42  ? -0.568  32.771  -21.304 1.00 25.13  ? 42  VAL A CG2 1 
ATOM   320   N  N   . ILE A 1 43  ? 1.262   35.030  -18.105 1.00 24.21  ? 43  ILE A N   1 
ATOM   321   C  CA  . ILE A 1 43  ? 2.458   35.873  -18.175 1.00 28.20  ? 43  ILE A CA  1 
ATOM   322   C  C   . ILE A 1 43  ? 3.574   35.427  -17.233 1.00 31.51  ? 43  ILE A C   1 
ATOM   323   O  O   . ILE A 1 43  ? 4.694   35.950  -17.332 1.00 30.49  ? 43  ILE A O   1 
ATOM   324   C  CB  . ILE A 1 43  ? 2.107   37.356  -17.916 1.00 22.04  ? 43  ILE A CB  1 
ATOM   325   C  CG1 . ILE A 1 43  ? 1.876   37.628  -16.432 1.00 23.08  ? 43  ILE A CG1 1 
ATOM   326   C  CG2 . ILE A 1 43  ? 0.887   37.774  -18.745 1.00 23.56  ? 43  ILE A CG2 1 
ATOM   327   C  CD1 . ILE A 1 43  ? 1.353   39.057  -16.139 1.00 19.81  ? 43  ILE A CD1 1 
ATOM   328   N  N   . CYS A 1 44  ? 3.341   34.425  -16.390 1.00 34.45  ? 44  CYS A N   1 
ATOM   329   C  CA  . CYS A 1 44  ? 4.361   33.957  -15.466 1.00 33.90  ? 44  CYS A CA  1 
ATOM   330   C  C   . CYS A 1 44  ? 5.283   32.942  -16.114 1.00 40.73  ? 44  CYS A C   1 
ATOM   331   O  O   . CYS A 1 44  ? 4.891   32.184  -17.008 1.00 35.14  ? 44  CYS A O   1 
ATOM   332   C  CB  . CYS A 1 44  ? 3.735   33.322  -14.229 1.00 37.85  ? 44  CYS A CB  1 
ATOM   333   S  SG  . CYS A 1 44  ? 2.720   34.439  -13.255 1.00 34.79  ? 44  CYS A SG  1 
ATOM   334   N  N   . THR A 1 45  ? 6.519   32.930  -15.637 1.00 49.40  ? 45  THR A N   1 
ATOM   335   C  CA  . THR A 1 45  ? 7.435   31.827  -15.876 1.00 58.35  ? 45  THR A CA  1 
ATOM   336   C  C   . THR A 1 45  ? 7.242   30.776  -14.783 1.00 65.96  ? 45  THR A C   1 
ATOM   337   O  O   . THR A 1 45  ? 6.584   31.014  -13.766 1.00 63.47  ? 45  THR A O   1 
ATOM   338   C  CB  . THR A 1 45  ? 8.877   32.338  -15.908 1.00 61.33  ? 45  THR A CB  1 
ATOM   339   O  OG1 . THR A 1 45  ? 9.309   32.652  -14.577 1.00 65.68  ? 45  THR A OG1 1 
ATOM   340   C  CG2 . THR A 1 45  ? 8.964   33.609  -16.750 1.00 51.76  ? 45  THR A CG2 1 
ATOM   341   N  N   . SER A 1 46  ? 7.821   29.593  -14.994 1.00 71.38  ? 46  SER A N   1 
ATOM   342   C  CA  . SER A 1 46  ? 7.757   28.573  -13.951 1.00 72.83  ? 46  SER A CA  1 
ATOM   343   C  C   . SER A 1 46  ? 8.443   29.042  -12.672 1.00 72.71  ? 46  SER A C   1 
ATOM   344   O  O   . SER A 1 46  ? 8.070   28.612  -11.574 1.00 69.24  ? 46  SER A O   1 
ATOM   345   C  CB  . SER A 1 46  ? 8.378   27.271  -14.449 1.00 68.97  ? 46  SER A CB  1 
ATOM   346   O  OG  . SER A 1 46  ? 7.487   26.605  -15.323 1.00 71.07  ? 46  SER A OG  1 
ATOM   347   N  N   . GLU A 1 47  ? 9.426   29.932  -12.793 1.00 68.47  ? 47  GLU A N   1 
ATOM   348   C  CA  . GLU A 1 47  ? 10.128  30.499  -11.650 1.00 69.57  ? 47  GLU A CA  1 
ATOM   349   C  C   . GLU A 1 47  ? 9.176   31.314  -10.783 1.00 72.21  ? 47  GLU A C   1 
ATOM   350   O  O   . GLU A 1 47  ? 8.882   30.940  -9.643  1.00 76.32  ? 47  GLU A O   1 
ATOM   351   C  CB  . GLU A 1 47  ? 11.297  31.373  -12.124 1.00 77.83  ? 47  GLU A CB  1 
ATOM   352   C  CG  . GLU A 1 47  ? 12.238  30.685  -13.130 1.00 84.17  ? 47  GLU A CG  1 
ATOM   353   C  CD  . GLU A 1 47  ? 12.961  31.651  -14.074 1.00 79.48  ? 47  GLU A CD  1 
ATOM   354   O  OE1 . GLU A 1 47  ? 12.479  32.791  -14.269 1.00 76.33  ? 47  GLU A OE1 1 
ATOM   355   O  OE2 . GLU A 1 47  ? 14.021  31.258  -14.621 1.00 73.34  ? 47  GLU A OE2 1 
ATOM   356   N  N   . ASP A 1 48  ? 8.666   32.415  -11.330 1.00 68.81  ? 48  ASP A N   1 
ATOM   357   C  CA  . ASP A 1 48  ? 7.905   33.387  -10.552 1.00 75.56  ? 48  ASP A CA  1 
ATOM   358   C  C   . ASP A 1 48  ? 6.486   32.921  -10.244 1.00 66.36  ? 48  ASP A C   1 
ATOM   359   O  O   . ASP A 1 48  ? 5.563   33.741  -10.212 1.00 62.06  ? 48  ASP A O   1 
ATOM   360   C  CB  . ASP A 1 48  ? 7.845   34.739  -11.282 1.00 79.16  ? 48  ASP A CB  1 
ATOM   361   C  CG  . ASP A 1 48  ? 9.113   35.573  -11.102 1.00 84.04  ? 48  ASP A CG  1 
ATOM   362   O  OD1 . ASP A 1 48  ? 10.111  35.059  -10.545 1.00 87.69  ? 48  ASP A OD1 1 
ATOM   363   O  OD2 . ASP A 1 48  ? 9.096   36.758  -11.505 1.00 77.52  ? 48  ASP A OD2 1 
ATOM   364   N  N   . MET A 1 49  ? 6.283   31.618  -10.049 1.00 59.32  ? 49  MET A N   1 
ATOM   365   C  CA  . MET A 1 49  ? 4.969   31.129  -9.652  1.00 51.54  ? 49  MET A CA  1 
ATOM   366   C  C   . MET A 1 49  ? 4.745   31.148  -8.143  1.00 45.65  ? 49  MET A C   1 
ATOM   367   O  O   . MET A 1 49  ? 3.592   31.065  -7.705  1.00 41.67  ? 49  MET A O   1 
ATOM   368   C  CB  . MET A 1 49  ? 4.752   29.707  -10.174 1.00 55.17  ? 49  MET A CB  1 
ATOM   369   C  CG  . MET A 1 49  ? 4.261   29.606  -11.623 1.00 60.34  ? 49  MET A CG  1 
ATOM   370   S  SD  . MET A 1 49  ? 2.552   30.129  -11.917 1.00 57.66  ? 49  MET A SD  1 
ATOM   371   C  CE  . MET A 1 49  ? 2.313   29.566  -13.604 1.00 41.91  ? 49  MET A CE  1 
ATOM   372   N  N   . LEU A 1 50  ? 5.806   31.261  -7.338  1.00 44.19  ? 50  LEU A N   1 
ATOM   373   C  CA  . LEU A 1 50  ? 5.637   31.205  -5.887  1.00 43.96  ? 50  LEU A CA  1 
ATOM   374   C  C   . LEU A 1 50  ? 4.879   32.421  -5.366  1.00 42.47  ? 50  LEU A C   1 
ATOM   375   O  O   . LEU A 1 50  ? 3.928   32.292  -4.586  1.00 40.73  ? 50  LEU A O   1 
ATOM   376   C  CB  . LEU A 1 50  ? 6.999   31.087  -5.199  1.00 38.06  ? 50  LEU A CB  1 
ATOM   377   C  CG  . LEU A 1 50  ? 7.676   29.712  -5.151  1.00 46.41  ? 50  LEU A CG  1 
ATOM   378   C  CD1 . LEU A 1 50  ? 9.036   29.790  -4.456  1.00 45.31  ? 50  LEU A CD1 1 
ATOM   379   C  CD2 . LEU A 1 50  ? 6.792   28.662  -4.488  1.00 31.56  ? 50  LEU A CD2 1 
ATOM   380   N  N   . ASN A 1 51  ? 5.284   33.611  -5.796  1.00 48.14  ? 51  ASN A N   1 
ATOM   381   C  CA  . ASN A 1 51  ? 4.647   34.859  -5.374  1.00 46.05  ? 51  ASN A CA  1 
ATOM   382   C  C   . ASN A 1 51  ? 4.743   35.863  -6.496  1.00 39.41  ? 51  ASN A C   1 
ATOM   383   O  O   . ASN A 1 51  ? 5.534   36.809  -6.441  1.00 34.60  ? 51  ASN A O   1 
ATOM   384   C  CB  . ASN A 1 51  ? 5.293   35.424  -4.109  1.00 49.54  ? 51  ASN A CB  1 
ATOM   385   C  CG  . ASN A 1 51  ? 4.420   35.253  -2.896  1.00 63.69  ? 51  ASN A CG  1 
ATOM   386   O  OD1 . ASN A 1 51  ? 3.508   36.063  -2.675  1.00 63.49  ? 51  ASN A OD1 1 
ATOM   387   N  ND2 . ASN A 1 51  ? 4.675   34.208  -2.103  1.00 59.94  ? 51  ASN A ND2 1 
ATOM   388   N  N   . PRO A 1 52  ? 3.895   35.731  -7.513  1.00 42.38  ? 52  PRO A N   1 
ATOM   389   C  CA  . PRO A 1 52  ? 4.023   36.600  -8.690  1.00 37.21  ? 52  PRO A CA  1 
ATOM   390   C  C   . PRO A 1 52  ? 3.394   37.957  -8.416  1.00 32.70  ? 52  PRO A C   1 
ATOM   391   O  O   . PRO A 1 52  ? 2.300   38.047  -7.855  1.00 29.08  ? 52  PRO A O   1 
ATOM   392   C  CB  . PRO A 1 52  ? 3.267   35.836  -9.782  1.00 32.84  ? 52  PRO A CB  1 
ATOM   393   C  CG  . PRO A 1 52  ? 2.244   35.014  -9.024  1.00 36.14  ? 52  PRO A CG  1 
ATOM   394   C  CD  . PRO A 1 52  ? 2.834   34.712  -7.663  1.00 38.56  ? 52  PRO A CD  1 
ATOM   395   N  N   . ASN A 1 53  ? 4.129   39.015  -8.753  1.00 31.33  ? 53  ASN A N   1 
ATOM   396   C  CA  . ASN A 1 53  ? 3.593   40.376  -8.728  1.00 34.25  ? 53  ASN A CA  1 
ATOM   397   C  C   . ASN A 1 53  ? 3.085   40.632  -10.133 1.00 29.35  ? 53  ASN A C   1 
ATOM   398   O  O   . ASN A 1 53  ? 3.837   41.027  -11.024 1.00 30.25  ? 53  ASN A O   1 
ATOM   399   C  CB  . ASN A 1 53  ? 4.650   41.394  -8.308  1.00 37.13  ? 53  ASN A CB  1 
ATOM   400   C  CG  . ASN A 1 53  ? 4.070   42.808  -8.111  1.00 38.88  ? 53  ASN A CG  1 
ATOM   401   O  OD1 . ASN A 1 53  ? 3.083   43.194  -8.751  1.00 32.53  ? 53  ASN A OD1 1 
ATOM   402   N  ND2 . ASN A 1 53  ? 4.671   43.567  -7.195  1.00 33.19  ? 53  ASN A ND2 1 
ATOM   403   N  N   . TYR A 1 54  ? 1.795   40.374  -10.337 1.00 30.55  ? 54  TYR A N   1 
ATOM   404   C  CA  . TYR A 1 54  ? 1.244   40.356  -11.694 1.00 29.44  ? 54  TYR A CA  1 
ATOM   405   C  C   . TYR A 1 54  ? 1.287   41.733  -12.353 1.00 26.79  ? 54  TYR A C   1 
ATOM   406   O  O   . TYR A 1 54  ? 1.568   41.834  -13.555 1.00 25.42  ? 54  TYR A O   1 
ATOM   407   C  CB  . TYR A 1 54  ? -0.183  39.811  -11.661 1.00 22.66  ? 54  TYR A CB  1 
ATOM   408   C  CG  . TYR A 1 54  ? -0.260  38.309  -11.536 1.00 27.47  ? 54  TYR A CG  1 
ATOM   409   C  CD1 . TYR A 1 54  ? -0.052  37.497  -12.640 1.00 26.11  ? 54  TYR A CD1 1 
ATOM   410   C  CD2 . TYR A 1 54  ? -0.538  37.697  -10.317 1.00 25.58  ? 54  TYR A CD2 1 
ATOM   411   C  CE1 . TYR A 1 54  ? -0.130  36.131  -12.538 1.00 20.33  ? 54  TYR A CE1 1 
ATOM   412   C  CE2 . TYR A 1 54  ? -0.625  36.330  -10.215 1.00 24.41  ? 54  TYR A CE2 1 
ATOM   413   C  CZ  . TYR A 1 54  ? -0.411  35.558  -11.325 1.00 25.29  ? 54  TYR A CZ  1 
ATOM   414   O  OH  . TYR A 1 54  ? -0.477  34.194  -11.234 1.00 25.92  ? 54  TYR A OH  1 
ATOM   415   N  N   . GLU A 1 55  ? 1.011   42.802  -11.587 1.00 25.21  ? 55  GLU A N   1 
ATOM   416   C  CA  . GLU A 1 55  ? 1.099   44.151  -12.143 1.00 30.51  ? 55  GLU A CA  1 
ATOM   417   C  C   . GLU A 1 55  ? 2.493   44.430  -12.669 1.00 29.14  ? 55  GLU A C   1 
ATOM   418   O  O   . GLU A 1 55  ? 2.659   44.970  -13.771 1.00 27.87  ? 55  GLU A O   1 
ATOM   419   C  CB  . GLU A 1 55  ? 0.752   45.208  -11.095 1.00 25.22  ? 55  GLU A CB  1 
ATOM   420   C  CG  . GLU A 1 55  ? -0.666  45.268  -10.642 1.00 40.59  ? 55  GLU A CG  1 
ATOM   421   C  CD  . GLU A 1 55  ? -0.875  46.418  -9.669  1.00 53.25  ? 55  GLU A CD  1 
ATOM   422   O  OE1 . GLU A 1 55  ? 0.127   46.850  -9.056  1.00 59.51  ? 55  GLU A OE1 1 
ATOM   423   O  OE2 . GLU A 1 55  ? -2.021  46.903  -9.519  1.00 64.13  ? 55  GLU A OE2 1 
ATOM   424   N  N   . ASP A 1 56  ? 3.508   44.057  -11.891 1.00 28.03  ? 56  ASP A N   1 
ATOM   425   C  CA  . ASP A 1 56  ? 4.881   44.262  -12.323 1.00 33.17  ? 56  ASP A CA  1 
ATOM   426   C  C   . ASP A 1 56  ? 5.163   43.439  -13.566 1.00 32.39  ? 56  ASP A C   1 
ATOM   427   O  O   . ASP A 1 56  ? 5.757   43.935  -14.534 1.00 32.51  ? 56  ASP A O   1 
ATOM   428   C  CB  . ASP A 1 56  ? 5.857   43.893  -11.194 1.00 37.47  ? 56  ASP A CB  1 
ATOM   429   C  CG  . ASP A 1 56  ? 5.857   44.913  -10.035 1.00 42.79  ? 56  ASP A CG  1 
ATOM   430   O  OD1 . ASP A 1 56  ? 5.122   45.929  -10.108 1.00 34.31  ? 56  ASP A OD1 1 
ATOM   431   O  OD2 . ASP A 1 56  ? 6.623   44.702  -9.053  1.00 48.95  ? 56  ASP A OD2 1 
ATOM   432   N  N   . LEU A 1 57  ? 4.699   42.191  -13.574 1.00 26.08  ? 57  LEU A N   1 
ATOM   433   C  CA  . LEU A 1 57  ? 4.892   41.339  -14.737 1.00 25.20  ? 57  LEU A CA  1 
ATOM   434   C  C   . LEU A 1 57  ? 4.159   41.886  -15.954 1.00 23.12  ? 57  LEU A C   1 
ATOM   435   O  O   . LEU A 1 57  ? 4.657   41.786  -17.078 1.00 23.39  ? 57  LEU A O   1 
ATOM   436   C  CB  . LEU A 1 57  ? 4.415   39.914  -14.431 1.00 25.66  ? 57  LEU A CB  1 
ATOM   437   C  CG  . LEU A 1 57  ? 5.140   39.100  -13.356 1.00 28.47  ? 57  LEU A CG  1 
ATOM   438   C  CD1 . LEU A 1 57  ? 4.311   37.866  -12.961 1.00 29.64  ? 57  LEU A CD1 1 
ATOM   439   C  CD2 . LEU A 1 57  ? 6.546   38.693  -13.804 1.00 27.13  ? 57  LEU A CD2 1 
ATOM   440   N  N   . LEU A 1 58  ? 2.957   42.439  -15.757 1.00 24.23  ? 58  LEU A N   1 
ATOM   441   C  CA  . LEU A 1 58  ? 2.147   42.840  -16.905 1.00 26.01  ? 58  LEU A CA  1 
ATOM   442   C  C   . LEU A 1 58  ? 2.723   44.071  -17.596 1.00 24.54  ? 58  LEU A C   1 
ATOM   443   O  O   . LEU A 1 58  ? 2.780   44.127  -18.826 1.00 21.28  ? 58  LEU A O   1 
ATOM   444   C  CB  . LEU A 1 58  ? 0.710   43.117  -16.474 1.00 22.88  ? 58  LEU A CB  1 
ATOM   445   C  CG  . LEU A 1 58  ? -0.251  43.303  -17.646 1.00 24.36  ? 58  LEU A CG  1 
ATOM   446   C  CD1 . LEU A 1 58  ? -0.223  42.055  -18.560 1.00 20.03  ? 58  LEU A CD1 1 
ATOM   447   C  CD2 . LEU A 1 58  ? -1.647  43.598  -17.162 1.00 21.39  ? 58  LEU A CD2 1 
ATOM   448   N  N   . ILE A 1 59  ? 3.219   45.033  -16.816 1.00 26.27  ? 59  ILE A N   1 
ATOM   449   C  CA  . ILE A 1 59  ? 3.705   46.293  -17.371 1.00 29.59  ? 59  ILE A CA  1 
ATOM   450   C  C   . ILE A 1 59  ? 4.917   46.071  -18.253 1.00 31.59  ? 59  ILE A C   1 
ATOM   451   O  O   . ILE A 1 59  ? 5.233   46.922  -19.094 1.00 27.04  ? 59  ILE A O   1 
ATOM   452   C  CB  . ILE A 1 59  ? 4.016   47.288  -16.230 1.00 27.02  ? 59  ILE A CB  1 
ATOM   453   C  CG1 . ILE A 1 59  ? 4.066   48.727  -16.739 1.00 27.54  ? 59  ILE A CG1 1 
ATOM   454   C  CG2 . ILE A 1 59  ? 5.315   46.930  -15.525 1.00 26.66  ? 59  ILE A CG2 1 
ATOM   455   C  CD1 . ILE A 1 59  ? 2.827   49.211  -17.458 1.00 28.04  ? 59  ILE A CD1 1 
ATOM   456   N  N   . ARG A 1 60  ? 5.601   44.939  -18.078 1.00 30.78  ? 60  ARG A N   1 
ATOM   457   C  CA  . ARG A 1 60  ? 6.761   44.590  -18.876 1.00 28.81  ? 60  ARG A CA  1 
ATOM   458   C  C   . ARG A 1 60  ? 6.401   43.989  -20.228 1.00 36.66  ? 60  ARG A C   1 
ATOM   459   O  O   . ARG A 1 60  ? 7.308   43.720  -21.031 1.00 41.70  ? 60  ARG A O   1 
ATOM   460   C  CB  . ARG A 1 60  ? 7.633   43.616  -18.086 1.00 35.18  ? 60  ARG A CB  1 
ATOM   461   C  CG  . ARG A 1 60  ? 8.142   44.189  -16.769 1.00 36.86  ? 60  ARG A CG  1 
ATOM   462   C  CD  . ARG A 1 60  ? 9.487   43.594  -16.396 1.00 43.91  ? 60  ARG A CD  1 
ATOM   463   N  NE  . ARG A 1 60  ? 9.370   42.571  -15.362 1.00 55.31  ? 60  ARG A NE  1 
ATOM   464   C  CZ  . ARG A 1 60  ? 9.382   42.818  -14.057 1.00 55.54  ? 60  ARG A CZ  1 
ATOM   465   N  NH1 . ARG A 1 60  ? 9.545   44.045  -13.584 1.00 56.53  ? 60  ARG A NH1 1 
ATOM   466   N  NH2 . ARG A 1 60  ? 9.228   41.808  -13.206 1.00 51.57  ? 60  ARG A NH2 1 
ATOM   467   N  N   . LYS A 1 61  ? 5.117   43.752  -20.497 1.00 33.12  ? 61  LYS A N   1 
ATOM   468   C  CA  . LYS A 1 61  ? 4.686   43.152  -21.749 1.00 28.18  ? 61  LYS A CA  1 
ATOM   469   C  C   . LYS A 1 61  ? 4.070   44.196  -22.665 1.00 26.25  ? 61  LYS A C   1 
ATOM   470   O  O   . LYS A 1 61  ? 3.487   45.184  -22.220 1.00 28.64  ? 61  LYS A O   1 
ATOM   471   C  CB  . LYS A 1 61  ? 3.651   42.035  -21.537 1.00 30.00  ? 61  LYS A CB  1 
ATOM   472   C  CG  . LYS A 1 61  ? 4.013   40.943  -20.548 1.00 32.67  ? 61  LYS A CG  1 
ATOM   473   C  CD  . LYS A 1 61  ? 4.977   39.937  -21.112 1.00 27.85  ? 61  LYS A CD  1 
ATOM   474   C  CE  . LYS A 1 61  ? 5.312   38.907  -20.040 1.00 35.18  ? 61  LYS A CE  1 
ATOM   475   N  NZ  . LYS A 1 61  ? 6.534   38.095  -20.382 1.00 47.13  ? 61  LYS A NZ  1 
ATOM   476   N  N   . SER A 1 62  ? 4.178   43.939  -23.953 1.00 26.25  ? 62  SER A N   1 
ATOM   477   C  CA  . SER A 1 62  ? 3.481   44.691  -24.969 1.00 27.76  ? 62  SER A CA  1 
ATOM   478   C  C   . SER A 1 62  ? 2.540   43.742  -25.691 1.00 25.47  ? 62  SER A C   1 
ATOM   479   O  O   . SER A 1 62  ? 2.623   42.527  -25.538 1.00 24.06  ? 62  SER A O   1 
ATOM   480   C  CB  . SER A 1 62  ? 4.469   45.345  -25.946 1.00 32.20  ? 62  SER A CB  1 
ATOM   481   O  OG  . SER A 1 62  ? 5.331   46.241  -25.266 1.00 28.60  ? 62  SER A OG  1 
ATOM   482   N  N   . ASN A 1 63  ? 1.647   44.323  -26.490 1.00 27.24  ? 63  ASN A N   1 
ATOM   483   C  CA  . ASN A 1 63  ? 0.672   43.558  -27.262 1.00 24.37  ? 63  ASN A CA  1 
ATOM   484   C  C   . ASN A 1 63  ? 1.322   42.468  -28.108 1.00 27.98  ? 63  ASN A C   1 
ATOM   485   O  O   . ASN A 1 63  ? 0.795   41.352  -28.213 1.00 29.65  ? 63  ASN A O   1 
ATOM   486   C  CB  . ASN A 1 63  ? -0.112  44.505  -28.152 1.00 25.37  ? 63  ASN A CB  1 
ATOM   487   C  CG  . ASN A 1 63  ? -0.973  45.460  -27.351 1.00 29.97  ? 63  ASN A CG  1 
ATOM   488   O  OD1 . ASN A 1 63  ? -1.361  45.183  -26.203 1.00 25.33  ? 63  ASN A OD1 1 
ATOM   489   N  ND2 . ASN A 1 63  ? -1.288  46.588  -27.956 1.00 32.95  ? 63  ASN A ND2 1 
ATOM   490   N  N   . HIS A 1 64  ? 2.469   42.762  -28.718 1.00 28.05  ? 64  HIS A N   1 
ATOM   491   C  CA  . HIS A 1 64  ? 3.081   41.767  -29.588 1.00 28.05  ? 64  HIS A CA  1 
ATOM   492   C  C   . HIS A 1 64  ? 3.737   40.624  -28.807 1.00 29.27  ? 64  HIS A C   1 
ATOM   493   O  O   . HIS A 1 64  ? 4.227   39.683  -29.436 1.00 28.78  ? 64  HIS A O   1 
ATOM   494   C  CB  . HIS A 1 64  ? 4.090   42.443  -30.514 1.00 21.57  ? 64  HIS A CB  1 
ATOM   495   C  CG  . HIS A 1 64  ? 5.377   42.830  -29.847 1.00 27.09  ? 64  HIS A CG  1 
ATOM   496   N  ND1 . HIS A 1 64  ? 5.551   44.037  -29.205 1.00 27.40  ? 64  HIS A ND1 1 
ATOM   497   C  CD2 . HIS A 1 64  ? 6.580   42.206  -29.798 1.00 32.58  ? 64  HIS A CD2 1 
ATOM   498   C  CE1 . HIS A 1 64  ? 6.789   44.121  -28.748 1.00 25.53  ? 64  HIS A CE1 1 
ATOM   499   N  NE2 . HIS A 1 64  ? 7.436   43.025  -29.097 1.00 30.00  ? 64  HIS A NE2 1 
ATOM   500   N  N   . ASN A 1 65  ? 3.782   40.687  -27.467 1.00 25.45  ? 65  ASN A N   1 
ATOM   501   C  CA  . ASN A 1 65  ? 4.254   39.548  -26.678 1.00 29.33  ? 65  ASN A CA  1 
ATOM   502   C  C   . ASN A 1 65  ? 3.175   38.487  -26.456 1.00 31.43  ? 65  ASN A C   1 
ATOM   503   O  O   . ASN A 1 65  ? 3.498   37.390  -25.988 1.00 30.90  ? 65  ASN A O   1 
ATOM   504   C  CB  . ASN A 1 65  ? 4.769   39.980  -25.301 1.00 27.41  ? 65  ASN A CB  1 
ATOM   505   C  CG  . ASN A 1 65  ? 5.951   40.922  -25.370 1.00 26.30  ? 65  ASN A CG  1 
ATOM   506   O  OD1 . ASN A 1 65  ? 6.026   41.881  -24.593 1.00 28.70  ? 65  ASN A OD1 1 
ATOM   507   N  ND2 . ASN A 1 65  ? 6.862   40.682  -26.297 1.00 22.99  ? 65  ASN A ND2 1 
ATOM   508   N  N   . PHE A 1 66  ? 1.905   38.797  -26.751 1.00 32.03  ? 66  PHE A N   1 
ATOM   509   C  CA  . PHE A 1 66  ? 0.789   37.867  -26.586 1.00 26.19  ? 66  PHE A CA  1 
ATOM   510   C  C   . PHE A 1 66  ? 0.469   37.210  -27.930 1.00 29.10  ? 66  PHE A C   1 
ATOM   511   O  O   . PHE A 1 66  ? -0.182  37.809  -28.791 1.00 28.84  ? 66  PHE A O   1 
ATOM   512   C  CB  . PHE A 1 66  ? -0.419  38.606  -26.027 1.00 23.55  ? 66  PHE A CB  1 
ATOM   513   C  CG  . PHE A 1 66  ? -0.186  39.195  -24.657 1.00 27.40  ? 66  PHE A CG  1 
ATOM   514   C  CD1 . PHE A 1 66  ? -0.122  38.374  -23.540 1.00 28.40  ? 66  PHE A CD1 1 
ATOM   515   C  CD2 . PHE A 1 66  ? -0.052  40.567  -24.486 1.00 28.36  ? 66  PHE A CD2 1 
ATOM   516   C  CE1 . PHE A 1 66  ? 0.095   38.907  -22.284 1.00 29.97  ? 66  PHE A CE1 1 
ATOM   517   C  CE2 . PHE A 1 66  ? 0.170   41.120  -23.230 1.00 25.82  ? 66  PHE A CE2 1 
ATOM   518   C  CZ  . PHE A 1 66  ? 0.236   40.290  -22.124 1.00 31.40  ? 66  PHE A CZ  1 
ATOM   519   N  N   . LEU A 1 67  ? 0.891   35.961  -28.095 1.00 26.00  ? 67  LEU A N   1 
ATOM   520   C  CA  . LEU A 1 67  ? 0.596   35.198  -29.298 1.00 23.78  ? 67  LEU A CA  1 
ATOM   521   C  C   . LEU A 1 67  ? -0.749  34.527  -29.100 1.00 25.99  ? 67  LEU A C   1 
ATOM   522   O  O   . LEU A 1 67  ? -0.879  33.617  -28.270 1.00 24.67  ? 67  LEU A O   1 
ATOM   523   C  CB  . LEU A 1 67  ? 1.682   34.163  -29.555 1.00 23.10  ? 67  LEU A CB  1 
ATOM   524   C  CG  . LEU A 1 67  ? 3.068   34.747  -29.326 1.00 32.55  ? 67  LEU A CG  1 
ATOM   525   C  CD1 . LEU A 1 67  ? 4.143   33.660  -29.396 1.00 30.86  ? 67  LEU A CD1 1 
ATOM   526   C  CD2 . LEU A 1 67  ? 3.348   35.922  -30.333 1.00 31.48  ? 67  LEU A CD2 1 
ATOM   527   N  N   . VAL A 1 68  ? -1.749  34.971  -29.865 1.00 26.13  ? 68  VAL A N   1 
ATOM   528   C  CA  . VAL A 1 68  ? -3.092  34.411  -29.815 1.00 25.24  ? 68  VAL A CA  1 
ATOM   529   C  C   . VAL A 1 68  ? -3.393  33.758  -31.151 1.00 28.64  ? 68  VAL A C   1 
ATOM   530   O  O   . VAL A 1 68  ? -3.132  34.345  -32.211 1.00 27.13  ? 68  VAL A O   1 
ATOM   531   C  CB  . VAL A 1 68  ? -4.150  35.471  -29.474 1.00 25.91  ? 68  VAL A CB  1 
ATOM   532   C  CG1 . VAL A 1 68  ? -5.545  34.826  -29.463 1.00 22.35  ? 68  VAL A CG1 1 
ATOM   533   C  CG2 . VAL A 1 68  ? -3.833  36.102  -28.142 1.00 23.83  ? 68  VAL A CG2 1 
ATOM   534   N  N   . GLN A 1 69  ? -3.944  32.553  -31.106 1.00 21.21  ? 69  GLN A N   1 
ATOM   535   C  CA  . GLN A 1 69  ? -4.158  31.792  -32.325 1.00 24.51  ? 69  GLN A CA  1 
ATOM   536   C  C   . GLN A 1 69  ? -5.514  31.107  -32.273 1.00 26.08  ? 69  GLN A C   1 
ATOM   537   O  O   . GLN A 1 69  ? -5.746  30.264  -31.403 1.00 24.12  ? 69  GLN A O   1 
ATOM   538   C  CB  . GLN A 1 69  ? -3.045  30.777  -32.496 1.00 29.31  ? 69  GLN A CB  1 
ATOM   539   C  CG  . GLN A 1 69  ? -2.963  30.226  -33.858 1.00 36.47  ? 69  GLN A CG  1 
ATOM   540   C  CD  . GLN A 1 69  ? -1.719  29.442  -33.993 1.00 37.89  ? 69  GLN A CD  1 
ATOM   541   O  OE1 . GLN A 1 69  ? -0.715  29.756  -33.348 1.00 39.09  ? 69  GLN A OE1 1 
ATOM   542   N  NE2 . GLN A 1 69  ? -1.748  28.418  -34.840 1.00 41.36  ? 69  GLN A NE2 1 
ATOM   543   N  N   . ALA A 1 70  ? -6.411  31.478  -33.190 1.00 26.07  ? 70  ALA A N   1 
ATOM   544   C  CA  . ALA A 1 70  ? -7.713  30.838  -33.306 1.00 21.69  ? 70  ALA A CA  1 
ATOM   545   C  C   . ALA A 1 70  ? -7.624  29.746  -34.362 1.00 26.61  ? 70  ALA A C   1 
ATOM   546   O  O   . ALA A 1 70  ? -7.643  30.034  -35.559 1.00 23.99  ? 70  ALA A O   1 
ATOM   547   C  CB  . ALA A 1 70  ? -8.785  31.858  -33.668 1.00 22.15  ? 70  ALA A CB  1 
ATOM   548   N  N   . GLY A 1 71  ? -7.588  28.497  -33.918 1.00 23.68  ? 71  GLY A N   1 
ATOM   549   C  CA  . GLY A 1 71  ? -7.291  27.404  -34.824 1.00 23.71  ? 71  GLY A CA  1 
ATOM   550   C  C   . GLY A 1 71  ? -5.929  27.629  -35.435 1.00 30.43  ? 71  GLY A C   1 
ATOM   551   O  O   . GLY A 1 71  ? -4.914  27.712  -34.732 1.00 36.06  ? 71  GLY A O   1 
ATOM   552   N  N   . ASN A 1 72  ? -5.882  27.808  -36.751 1.00 34.03  ? 72  ASN A N   1 
ATOM   553   C  CA  . ASN A 1 72  ? -4.607  27.988  -37.428 1.00 40.55  ? 72  ASN A CA  1 
ATOM   554   C  C   . ASN A 1 72  ? -4.333  29.432  -37.859 1.00 43.98  ? 72  ASN A C   1 
ATOM   555   O  O   . ASN A 1 72  ? -3.280  29.693  -38.454 1.00 42.63  ? 72  ASN A O   1 
ATOM   556   C  CB  . ASN A 1 72  ? -4.510  27.043  -38.628 1.00 43.48  ? 72  ASN A CB  1 
ATOM   557   C  CG  . ASN A 1 72  ? -3.086  26.603  -38.888 1.00 58.90  ? 72  ASN A CG  1 
ATOM   558   O  OD1 . ASN A 1 72  ? -2.677  25.506  -38.485 1.00 53.59  ? 72  ASN A OD1 1 
ATOM   559   N  ND2 . ASN A 1 72  ? -2.311  27.465  -39.549 1.00 59.61  ? 72  ASN A ND2 1 
ATOM   560   N  N   . VAL A 1 73  ? -5.258  30.365  -37.625 1.00 36.98  ? 73  VAL A N   1 
ATOM   561   C  CA  . VAL A 1 73  ? -5.067  31.758  -38.009 1.00 36.89  ? 73  VAL A CA  1 
ATOM   562   C  C   . VAL A 1 73  ? -4.610  32.553  -36.785 1.00 36.16  ? 73  VAL A C   1 
ATOM   563   O  O   . VAL A 1 73  ? -5.204  32.456  -35.701 1.00 32.26  ? 73  VAL A O   1 
ATOM   564   C  CB  . VAL A 1 73  ? -6.340  32.349  -38.643 1.00 29.97  ? 73  VAL A CB  1 
ATOM   565   C  CG1 . VAL A 1 73  ? -7.541  32.137  -37.757 1.00 35.45  ? 73  VAL A CG1 1 
ATOM   566   C  CG2 . VAL A 1 73  ? -6.140  33.826  -38.920 1.00 33.94  ? 73  VAL A CG2 1 
ATOM   567   N  N   . GLN A 1 74  ? -3.546  33.337  -36.967 1.00 33.67  ? 74  GLN A N   1 
ATOM   568   C  CA  . GLN A 1 74  ? -2.983  34.188  -35.926 1.00 27.38  ? 74  GLN A CA  1 
ATOM   569   C  C   . GLN A 1 74  ? -3.807  35.471  -35.802 1.00 30.90  ? 74  GLN A C   1 
ATOM   570   O  O   . GLN A 1 74  ? -4.126  36.109  -36.812 1.00 30.61  ? 74  GLN A O   1 
ATOM   571   C  CB  . GLN A 1 74  ? -1.539  34.515  -36.289 1.00 25.28  ? 74  GLN A CB  1 
ATOM   572   C  CG  . GLN A 1 74  ? -0.659  35.066  -35.196 1.00 30.14  ? 74  GLN A CG  1 
ATOM   573   C  CD  . GLN A 1 74  ? -0.319  34.023  -34.140 1.00 34.08  ? 74  GLN A CD  1 
ATOM   574   O  OE1 . GLN A 1 74  ? -0.279  32.816  -34.420 1.00 32.86  ? 74  GLN A OE1 1 
ATOM   575   N  NE2 . GLN A 1 74  ? -0.024  34.486  -32.929 1.00 31.48  ? 74  GLN A NE2 1 
ATOM   576   N  N   . LEU A 1 75  ? -4.185  35.828  -34.576 1.00 26.73  ? 75  LEU A N   1 
ATOM   577   C  CA  . LEU A 1 75  ? -4.872  37.087  -34.319 1.00 24.57  ? 75  LEU A CA  1 
ATOM   578   C  C   . LEU A 1 75  ? -3.894  38.200  -33.919 1.00 26.45  ? 75  LEU A C   1 
ATOM   579   O  O   . LEU A 1 75  ? -2.780  37.950  -33.449 1.00 28.95  ? 75  LEU A O   1 
ATOM   580   C  CB  . LEU A 1 75  ? -5.924  36.916  -33.228 1.00 21.27  ? 75  LEU A CB  1 
ATOM   581   C  CG  . LEU A 1 75  ? -6.941  35.790  -33.362 1.00 25.28  ? 75  LEU A CG  1 
ATOM   582   C  CD1 . LEU A 1 75  ? -7.993  35.947  -32.290 1.00 23.33  ? 75  LEU A CD1 1 
ATOM   583   C  CD2 . LEU A 1 75  ? -7.579  35.757  -34.731 1.00 27.37  ? 75  LEU A CD2 1 
ATOM   584   N  N   . ARG A 1 76  ? -4.333  39.444  -34.115 1.00 23.78  ? 76  ARG A N   1 
ATOM   585   C  CA  . ARG A 1 76  ? -3.505  40.626  -33.894 1.00 26.67  ? 76  ARG A CA  1 
ATOM   586   C  C   . ARG A 1 76  ? -3.982  41.355  -32.642 1.00 22.15  ? 76  ARG A C   1 
ATOM   587   O  O   . ARG A 1 76  ? -5.135  41.785  -32.569 1.00 24.04  ? 76  ARG A O   1 
ATOM   588   C  CB  . ARG A 1 76  ? -3.528  41.557  -35.114 1.00 30.11  ? 76  ARG A CB  1 
ATOM   589   C  CG  . ARG A 1 76  ? -2.619  42.792  -34.998 1.00 26.62  ? 76  ARG A CG  1 
ATOM   590   C  CD  . ARG A 1 76  ? -2.665  43.602  -36.286 1.00 35.04  ? 76  ARG A CD  1 
ATOM   591   N  NE  . ARG A 1 76  ? -2.170  42.846  -37.433 1.00 36.68  ? 76  ARG A NE  1 
ATOM   592   C  CZ  . ARG A 1 76  ? -0.907  42.845  -37.842 1.00 30.39  ? 76  ARG A CZ  1 
ATOM   593   N  NH1 . ARG A 1 76  ? 0.019   43.571  -37.238 1.00 20.52  ? 76  ARG A NH1 1 
ATOM   594   N  NH2 . ARG A 1 76  ? -0.564  42.086  -38.875 1.00 33.42  ? 76  ARG A NH2 1 
ATOM   595   N  N   . VAL A 1 77  ? -3.094  41.485  -31.665 1.00 21.61  ? 77  VAL A N   1 
ATOM   596   C  CA  . VAL A 1 77  ? -3.429  42.065  -30.370 1.00 26.00  ? 77  VAL A CA  1 
ATOM   597   C  C   . VAL A 1 77  ? -3.197  43.571  -30.412 1.00 26.88  ? 77  VAL A C   1 
ATOM   598   O  O   . VAL A 1 77  ? -2.074  44.030  -30.663 1.00 25.19  ? 77  VAL A O   1 
ATOM   599   C  CB  . VAL A 1 77  ? -2.598  41.410  -29.262 1.00 28.20  ? 77  VAL A CB  1 
ATOM   600   C  CG1 . VAL A 1 77  ? -2.859  42.099  -27.925 1.00 23.92  ? 77  VAL A CG1 1 
ATOM   601   C  CG2 . VAL A 1 77  ? -2.903  39.916  -29.200 1.00 17.94  ? 77  VAL A CG2 1 
ATOM   602   N  N   . ILE A 1 78  ? -4.251  44.351  -30.168 1.00 29.10  ? 78  ILE A N   1 
ATOM   603   C  CA  . ILE A 1 78  ? -4.129  45.805  -30.221 1.00 29.78  ? 78  ILE A CA  1 
ATOM   604   C  C   . ILE A 1 78  ? -4.325  46.463  -28.869 1.00 30.46  ? 78  ILE A C   1 
ATOM   605   O  O   . ILE A 1 78  ? -4.299  47.696  -28.798 1.00 30.09  ? 78  ILE A O   1 
ATOM   606   C  CB  . ILE A 1 78  ? -5.077  46.438  -31.259 1.00 30.15  ? 78  ILE A CB  1 
ATOM   607   C  CG1 . ILE A 1 78  ? -6.538  46.202  -30.883 1.00 31.82  ? 78  ILE A CG1 1 
ATOM   608   C  CG2 . ILE A 1 78  ? -4.746  45.913  -32.652 1.00 27.62  ? 78  ILE A CG2 1 
ATOM   609   C  CD1 . ILE A 1 78  ? -7.502  46.819  -31.829 1.00 27.80  ? 78  ILE A CD1 1 
ATOM   610   N  N   . GLY A 1 79  ? -4.549  45.693  -27.804 1.00 29.54  ? 79  GLY A N   1 
ATOM   611   C  CA  . GLY A 1 79  ? -4.628  46.249  -26.464 1.00 23.13  ? 79  GLY A CA  1 
ATOM   612   C  C   . GLY A 1 79  ? -4.691  45.133  -25.448 1.00 28.21  ? 79  GLY A C   1 
ATOM   613   O  O   . GLY A 1 79  ? -5.002  43.987  -25.782 1.00 29.76  ? 79  GLY A O   1 
ATOM   614   N  N   . HIS A 1 80  ? -4.361  45.469  -24.202 1.00 26.63  ? 80  HIS A N   1 
ATOM   615   C  CA  . HIS A 1 80  ? -4.454  44.480  -23.140 1.00 26.00  ? 80  HIS A CA  1 
ATOM   616   C  C   . HIS A 1 80  ? -4.689  45.184  -21.816 1.00 29.43  ? 80  HIS A C   1 
ATOM   617   O  O   . HIS A 1 80  ? -4.361  46.365  -21.655 1.00 29.22  ? 80  HIS A O   1 
ATOM   618   C  CB  . HIS A 1 80  ? -3.216  43.569  -23.058 1.00 25.04  ? 80  HIS A CB  1 
ATOM   619   C  CG  . HIS A 1 80  ? -1.964  44.246  -22.585 1.00 28.88  ? 80  HIS A CG  1 
ATOM   620   N  ND1 . HIS A 1 80  ? -1.088  44.884  -23.441 1.00 28.73  ? 80  HIS A ND1 1 
ATOM   621   C  CD2 . HIS A 1 80  ? -1.398  44.307  -21.354 1.00 27.32  ? 80  HIS A CD2 1 
ATOM   622   C  CE1 . HIS A 1 80  ? -0.055  45.339  -22.750 1.00 30.23  ? 80  HIS A CE1 1 
ATOM   623   N  NE2 . HIS A 1 80  ? -0.216  44.999  -21.482 1.00 30.22  ? 80  HIS A NE2 1 
ATOM   624   N  N   . SER A 1 81  ? -5.316  44.458  -20.894 1.00 23.93  ? 81  SER A N   1 
ATOM   625   C  CA  . SER A 1 81  ? -5.537  44.931  -19.535 1.00 26.87  ? 81  SER A CA  1 
ATOM   626   C  C   . SER A 1 81  ? -5.770  43.737  -18.617 1.00 28.92  ? 81  SER A C   1 
ATOM   627   O  O   . SER A 1 81  ? -5.960  42.602  -19.062 1.00 27.16  ? 81  SER A O   1 
ATOM   628   C  CB  . SER A 1 81  ? -6.715  45.897  -19.470 1.00 25.46  ? 81  SER A CB  1 
ATOM   629   O  OG  . SER A 1 81  ? -7.864  45.265  -19.982 1.00 32.63  ? 81  SER A OG  1 
ATOM   630   N  N   . MET A 1 82  ? -5.724  44.007  -17.318 1.00 26.49  ? 82  MET A N   1 
ATOM   631   C  CA  . MET A 1 82  ? -5.936  42.997  -16.297 1.00 23.66  ? 82  MET A CA  1 
ATOM   632   C  C   . MET A 1 82  ? -7.195  43.363  -15.527 1.00 26.27  ? 82  MET A C   1 
ATOM   633   O  O   . MET A 1 82  ? -7.413  44.537  -15.215 1.00 30.38  ? 82  MET A O   1 
ATOM   634   C  CB  . MET A 1 82  ? -4.732  42.903  -15.374 1.00 25.78  ? 82  MET A CB  1 
ATOM   635   C  CG  . MET A 1 82  ? -4.817  41.824  -14.339 1.00 21.28  ? 82  MET A CG  1 
ATOM   636   S  SD  . MET A 1 82  ? -3.163  41.473  -13.694 1.00 31.70  ? 82  MET A SD  1 
ATOM   637   C  CE  . MET A 1 82  ? -2.742  42.973  -12.799 1.00 25.28  ? 82  MET A CE  1 
ATOM   638   N  N   . GLN A 1 83  ? -8.065  42.382  -15.311 1.00 25.13  ? 83  GLN A N   1 
ATOM   639   C  CA  . GLN A 1 83  ? -9.245  42.535  -14.474 1.00 21.67  ? 83  GLN A CA  1 
ATOM   640   C  C   . GLN A 1 83  ? -9.242  41.363  -13.503 1.00 22.81  ? 83  GLN A C   1 
ATOM   641   O  O   . GLN A 1 83  ? -9.546  40.237  -13.902 1.00 26.33  ? 83  GLN A O   1 
ATOM   642   C  CB  . GLN A 1 83  ? -10.513 42.535  -15.313 1.00 23.24  ? 83  GLN A CB  1 
ATOM   643   C  CG  . GLN A 1 83  ? -11.763 42.494  -14.495 1.00 24.38  ? 83  GLN A CG  1 
ATOM   644   C  CD  . GLN A 1 83  ? -13.013 42.557  -15.340 1.00 30.75  ? 83  GLN A CD  1 
ATOM   645   O  OE1 . GLN A 1 83  ? -13.017 42.140  -16.504 1.00 24.96  ? 83  GLN A OE1 1 
ATOM   646   N  NE2 . GLN A 1 83  ? -14.090 43.098  -14.762 1.00 31.50  ? 83  GLN A NE2 1 
ATOM   647   N  N   . ASN A 1 84  ? -8.924  41.623  -12.237 1.00 18.32  ? 84  ASN A N   1 
ATOM   648   C  CA  . ASN A 1 84  ? -8.729  40.575  -11.239 1.00 24.25  ? 84  ASN A CA  1 
ATOM   649   C  C   . ASN A 1 84  ? -7.781  39.495  -11.774 1.00 24.46  ? 84  ASN A C   1 
ATOM   650   O  O   . ASN A 1 84  ? -6.622  39.790  -12.119 1.00 24.31  ? 84  ASN A O   1 
ATOM   651   C  CB  . ASN A 1 84  ? -10.088 39.994  -10.796 1.00 19.18  ? 84  ASN A CB  1 
ATOM   652   C  CG  . ASN A 1 84  ? -11.034 41.080  -10.223 1.00 21.93  ? 84  ASN A CG  1 
ATOM   653   O  OD1 . ASN A 1 84  ? -12.162 41.274  -10.707 1.00 21.20  ? 84  ASN A OD1 1 
ATOM   654   N  ND2 . ASN A 1 84  ? -10.571 41.786  -9.195  1.00 14.38  ? 84  ASN A ND2 1 
ATOM   655   N  N   . CYS A 1 85  ? -8.244  38.250  -11.883 1.00 18.70  ? 85  CYS A N   1 
ATOM   656   C  CA  . CYS A 1 85  ? -7.332  37.191  -12.289 1.00 23.12  ? 85  CYS A CA  1 
ATOM   657   C  C   . CYS A 1 85  ? -7.456  36.813  -13.763 1.00 21.10  ? 85  CYS A C   1 
ATOM   658   O  O   . CYS A 1 85  ? -6.781  35.874  -14.197 1.00 19.48  ? 85  CYS A O   1 
ATOM   659   C  CB  . CYS A 1 85  ? -7.517  35.954  -11.407 1.00 20.11  ? 85  CYS A CB  1 
ATOM   660   S  SG  . CYS A 1 85  ? -7.103  36.237  -9.682  1.00 24.24  ? 85  CYS A SG  1 
ATOM   661   N  N   . VAL A 1 86  ? -8.242  37.546  -14.559 1.00 19.18  ? 86  VAL A N   1 
ATOM   662   C  CA  . VAL A 1 86  ? -8.317  37.264  -15.984 1.00 22.27  ? 86  VAL A CA  1 
ATOM   663   C  C   . VAL A 1 86  ? -7.628  38.373  -16.749 1.00 24.69  ? 86  VAL A C   1 
ATOM   664   O  O   . VAL A 1 86  ? -7.639  39.546  -16.361 1.00 29.91  ? 86  VAL A O   1 
ATOM   665   C  CB  . VAL A 1 86  ? -9.740  37.092  -16.551 1.00 29.61  ? 86  VAL A CB  1 
ATOM   666   C  CG1 . VAL A 1 86  ? -10.431 35.846  -15.954 1.00 28.86  ? 86  VAL A CG1 1 
ATOM   667   C  CG2 . VAL A 1 86  ? -10.527 38.364  -16.393 1.00 24.53  ? 86  VAL A CG2 1 
ATOM   668   N  N   . LEU A 1 87  ? -7.017  37.978  -17.851 1.00 22.68  ? 87  LEU A N   1 
ATOM   669   C  CA  . LEU A 1 87  ? -6.420  38.887  -18.807 1.00 22.43  ? 87  LEU A CA  1 
ATOM   670   C  C   . LEU A 1 87  ? -7.407  39.137  -19.941 1.00 25.37  ? 87  LEU A C   1 
ATOM   671   O  O   . LEU A 1 87  ? -8.050  38.202  -20.435 1.00 25.54  ? 87  LEU A O   1 
ATOM   672   C  CB  . LEU A 1 87  ? -5.141  38.260  -19.337 1.00 27.43  ? 87  LEU A CB  1 
ATOM   673   C  CG  . LEU A 1 87  ? -4.015  39.124  -19.842 1.00 33.39  ? 87  LEU A CG  1 
ATOM   674   C  CD1 . LEU A 1 87  ? -3.473  39.914  -18.647 1.00 34.23  ? 87  LEU A CD1 1 
ATOM   675   C  CD2 . LEU A 1 87  ? -2.961  38.192  -20.449 1.00 25.59  ? 87  LEU A CD2 1 
ATOM   676   N  N   . LYS A 1 88  ? -7.500  40.383  -20.387 1.00 21.37  ? 88  LYS A N   1 
ATOM   677   C  CA  . LYS A 1 88  ? -8.380  40.728  -21.496 1.00 21.89  ? 88  LYS A CA  1 
ATOM   678   C  C   . LYS A 1 88  ? -7.515  41.252  -22.634 1.00 24.20  ? 88  LYS A C   1 
ATOM   679   O  O   . LYS A 1 88  ? -6.914  42.329  -22.527 1.00 22.13  ? 88  LYS A O   1 
ATOM   680   C  CB  . LYS A 1 88  ? -9.438  41.749  -21.079 1.00 19.28  ? 88  LYS A CB  1 
ATOM   681   C  CG  . LYS A 1 88  ? -10.345 41.244  -19.993 1.00 19.35  ? 88  LYS A CG  1 
ATOM   682   C  CD  . LYS A 1 88  ? -11.676 41.991  -19.948 1.00 25.52  ? 88  LYS A CD  1 
ATOM   683   C  CE  . LYS A 1 88  ? -11.606 43.335  -19.217 1.00 23.47  ? 88  LYS A CE  1 
ATOM   684   N  NZ  . LYS A 1 88  ? -12.980 43.830  -18.897 1.00 25.13  ? 88  LYS A NZ  1 
ATOM   685   N  N   . LEU A 1 89  ? -7.442  40.477  -23.717 1.00 19.32  ? 89  LEU A N   1 
ATOM   686   C  CA  . LEU A 1 89  ? -6.633  40.841  -24.869 1.00 25.56  ? 89  LEU A CA  1 
ATOM   687   C  C   . LEU A 1 89  ? -7.573  41.354  -25.960 1.00 22.12  ? 89  LEU A C   1 
ATOM   688   O  O   . LEU A 1 89  ? -8.368  40.591  -26.519 1.00 24.17  ? 89  LEU A O   1 
ATOM   689   C  CB  . LEU A 1 89  ? -5.779  39.665  -25.354 1.00 21.12  ? 89  LEU A CB  1 
ATOM   690   C  CG  . LEU A 1 89  ? -4.856  38.946  -24.341 1.00 25.89  ? 89  LEU A CG  1 
ATOM   691   C  CD1 . LEU A 1 89  ? -4.013  37.878  -25.039 1.00 21.66  ? 89  LEU A CD1 1 
ATOM   692   C  CD2 . LEU A 1 89  ? -3.949  39.892  -23.550 1.00 23.37  ? 89  LEU A CD2 1 
ATOM   693   N  N   . LYS A 1 90  ? -7.492  42.649  -26.252 1.00 22.61  ? 90  LYS A N   1 
ATOM   694   C  CA  . LYS A 1 90  ? -8.253  43.199  -27.365 1.00 23.68  ? 90  LYS A CA  1 
ATOM   695   C  C   . LYS A 1 90  ? -7.561  42.893  -28.687 1.00 23.73  ? 90  LYS A C   1 
ATOM   696   O  O   . LYS A 1 90  ? -6.359  43.120  -28.841 1.00 23.91  ? 90  LYS A O   1 
ATOM   697   C  CB  . LYS A 1 90  ? -8.475  44.694  -27.199 1.00 24.23  ? 90  LYS A CB  1 
ATOM   698   C  CG  . LYS A 1 90  ? -9.437  45.239  -28.245 1.00 28.71  ? 90  LYS A CG  1 
ATOM   699   C  CD  . LYS A 1 90  ? -9.955  46.610  -27.867 1.00 34.12  ? 90  LYS A CD  1 
ATOM   700   C  CE  . LYS A 1 90  ? -10.954 47.136  -28.899 1.00 44.58  ? 90  LYS A CE  1 
ATOM   701   N  NZ  . LYS A 1 90  ? -10.262 47.699  -30.115 1.00 40.83  ? 90  LYS A NZ  1 
ATOM   702   N  N   . VAL A 1 91  ? -8.320  42.333  -29.622 1.00 22.19  ? 91  VAL A N   1 
ATOM   703   C  CA  . VAL A 1 91  ? -7.837  41.998  -30.955 1.00 25.80  ? 91  VAL A CA  1 
ATOM   704   C  C   . VAL A 1 91  ? -8.576  42.832  -32.003 1.00 23.56  ? 91  VAL A C   1 
ATOM   705   O  O   . VAL A 1 91  ? -9.628  43.419  -31.739 1.00 22.32  ? 91  VAL A O   1 
ATOM   706   C  CB  . VAL A 1 91  ? -8.009  40.502  -31.225 1.00 22.78  ? 91  VAL A CB  1 
ATOM   707   C  CG1 . VAL A 1 91  ? -7.082  39.695  -30.304 1.00 19.78  ? 91  VAL A CG1 1 
ATOM   708   C  CG2 . VAL A 1 91  ? -9.464  40.131  -31.010 1.00 19.76  ? 91  VAL A CG2 1 
ATOM   709   N  N   . ASP A 1 92  ? -8.011  42.891  -33.205 1.00 18.72  ? 92  ASP A N   1 
ATOM   710   C  CA  . ASP A 1 92  ? -8.604  43.758  -34.223 1.00 29.40  ? 92  ASP A CA  1 
ATOM   711   C  C   . ASP A 1 92  ? -9.755  43.110  -34.980 1.00 27.10  ? 92  ASP A C   1 
ATOM   712   O  O   . ASP A 1 92  ? -10.348 43.751  -35.850 1.00 28.42  ? 92  ASP A O   1 
ATOM   713   C  CB  . ASP A 1 92  ? -7.539  44.217  -35.230 1.00 35.77  ? 92  ASP A CB  1 
ATOM   714   C  CG  . ASP A 1 92  ? -7.000  43.080  -36.078 1.00 33.41  ? 92  ASP A CG  1 
ATOM   715   O  OD1 . ASP A 1 92  ? -7.357  41.907  -35.818 1.00 45.36  ? 92  ASP A OD1 1 
ATOM   716   O  OD2 . ASP A 1 92  ? -6.234  43.364  -37.020 1.00 36.14  ? 92  ASP A OD2 1 
ATOM   717   N  N   . THR A 1 93  ? -10.087 41.866  -34.673 1.00 27.03  ? 93  THR A N   1 
ATOM   718   C  CA  . THR A 1 93  ? -11.078 41.102  -35.413 1.00 29.24  ? 93  THR A CA  1 
ATOM   719   C  C   . THR A 1 93  ? -12.157 40.609  -34.466 1.00 28.43  ? 93  THR A C   1 
ATOM   720   O  O   . THR A 1 93  ? -11.846 40.039  -33.421 1.00 28.51  ? 93  THR A O   1 
ATOM   721   C  CB  . THR A 1 93  ? -10.403 39.920  -36.107 1.00 36.63  ? 93  THR A CB  1 
ATOM   722   O  OG1 . THR A 1 93  ? -9.355  40.412  -36.957 1.00 37.23  ? 93  THR A OG1 1 
ATOM   723   C  CG2 . THR A 1 93  ? -11.411 39.091  -36.897 1.00 37.67  ? 93  THR A CG2 1 
ATOM   724   N  N   . ALA A 1 94  ? -13.412 40.868  -34.806 1.00 26.35  ? 94  ALA A N   1 
ATOM   725   C  CA  . ALA A 1 94  ? -14.516 40.279  -34.073 1.00 22.70  ? 94  ALA A CA  1 
ATOM   726   C  C   . ALA A 1 94  ? -14.639 38.804  -34.448 1.00 32.50  ? 94  ALA A C   1 
ATOM   727   O  O   . ALA A 1 94  ? -14.496 38.440  -35.621 1.00 28.13  ? 94  ALA A O   1 
ATOM   728   C  CB  . ALA A 1 94  ? -15.817 41.018  -34.373 1.00 20.28  ? 94  ALA A CB  1 
ATOM   729   N  N   . ASN A 1 95  ? -14.832 37.952  -33.437 1.00 23.60  ? 95  ASN A N   1 
ATOM   730   C  CA  . ASN A 1 95  ? -15.016 36.518  -33.642 1.00 24.35  ? 95  ASN A CA  1 
ATOM   731   C  C   . ASN A 1 95  ? -16.319 36.291  -34.392 1.00 24.53  ? 95  ASN A C   1 
ATOM   732   O  O   . ASN A 1 95  ? -17.394 36.487  -33.808 1.00 21.95  ? 95  ASN A O   1 
ATOM   733   C  CB  . ASN A 1 95  ? -15.041 35.775  -32.308 1.00 22.15  ? 95  ASN A CB  1 
ATOM   734   C  CG  . ASN A 1 95  ? -15.176 34.268  -32.485 1.00 26.90  ? 95  ASN A CG  1 
ATOM   735   O  OD1 . ASN A 1 95  ? -15.194 33.770  -33.611 1.00 26.47  ? 95  ASN A OD1 1 
ATOM   736   N  ND2 . ASN A 1 95  ? -15.276 33.536  -31.370 1.00 23.13  ? 95  ASN A ND2 1 
ATOM   737   N  N   . PRO A 1 96  ? -16.282 35.844  -35.650 1.00 25.85  ? 96  PRO A N   1 
ATOM   738   C  CA  . PRO A 1 96  ? -17.535 35.643  -36.397 1.00 27.82  ? 96  PRO A CA  1 
ATOM   739   C  C   . PRO A 1 96  ? -18.441 34.592  -35.798 1.00 25.91  ? 96  PRO A C   1 
ATOM   740   O  O   . PRO A 1 96  ? -19.644 34.610  -36.073 1.00 27.62  ? 96  PRO A O   1 
ATOM   741   C  CB  . PRO A 1 96  ? -17.049 35.225  -37.791 1.00 25.37  ? 96  PRO A CB  1 
ATOM   742   C  CG  . PRO A 1 96  ? -15.696 34.667  -37.574 1.00 24.75  ? 96  PRO A CG  1 
ATOM   743   C  CD  . PRO A 1 96  ? -15.101 35.435  -36.428 1.00 25.29  ? 96  PRO A CD  1 
ATOM   744   N  N   . LYS A 1 97  ? -17.902 33.688  -34.985 1.00 25.06  ? 97  LYS A N   1 
ATOM   745   C  CA  . LYS A 1 97  ? -18.666 32.633  -34.343 1.00 24.34  ? 97  LYS A CA  1 
ATOM   746   C  C   . LYS A 1 97  ? -19.122 33.018  -32.943 1.00 24.88  ? 97  LYS A C   1 
ATOM   747   O  O   . LYS A 1 97  ? -19.481 32.134  -32.159 1.00 26.81  ? 97  LYS A O   1 
ATOM   748   C  CB  . LYS A 1 97  ? -17.848 31.343  -34.284 1.00 25.21  ? 97  LYS A CB  1 
ATOM   749   C  CG  . LYS A 1 97  ? -17.527 30.718  -35.628 1.00 25.49  ? 97  LYS A CG  1 
ATOM   750   C  CD  . LYS A 1 97  ? -16.778 29.412  -35.416 1.00 33.87  ? 97  LYS A CD  1 
ATOM   751   C  CE  . LYS A 1 97  ? -15.941 29.031  -36.624 1.00 43.62  ? 97  LYS A CE  1 
ATOM   752   N  NZ  . LYS A 1 97  ? -14.985 27.903  -36.307 1.00 53.26  ? 97  LYS A NZ  1 
ATOM   753   N  N   . THR A 1 98  ? -19.045 34.298  -32.583 1.00 24.58  ? 98  THR A N   1 
ATOM   754   C  CA  . THR A 1 98  ? -19.472 34.696  -31.251 1.00 25.69  ? 98  THR A CA  1 
ATOM   755   C  C   . THR A 1 98  ? -20.937 34.335  -31.041 1.00 24.40  ? 98  THR A C   1 
ATOM   756   O  O   . THR A 1 98  ? -21.796 34.785  -31.813 1.00 25.63  ? 98  THR A O   1 
ATOM   757   C  CB  . THR A 1 98  ? -19.277 36.184  -31.006 1.00 25.62  ? 98  THR A CB  1 
ATOM   758   O  OG1 . THR A 1 98  ? -17.909 36.510  -31.249 1.00 27.73  ? 98  THR A OG1 1 
ATOM   759   C  CG2 . THR A 1 98  ? -19.603 36.521  -29.536 1.00 21.68  ? 98  THR A CG2 1 
ATOM   760   N  N   . PRO A 1 99  ? -21.263 33.554  -30.020 1.00 23.44  ? 99  PRO A N   1 
ATOM   761   C  CA  . PRO A 1 99  ? -22.660 33.303  -29.685 1.00 17.39  ? 99  PRO A CA  1 
ATOM   762   C  C   . PRO A 1 99  ? -23.219 34.451  -28.866 1.00 19.82  ? 99  PRO A C   1 
ATOM   763   O  O   . PRO A 1 99  ? -22.486 35.247  -28.284 1.00 23.91  ? 99  PRO A O   1 
ATOM   764   C  CB  . PRO A 1 99  ? -22.557 32.050  -28.816 1.00 24.33  ? 99  PRO A CB  1 
ATOM   765   C  CG  . PRO A 1 99  ? -21.278 32.267  -28.078 1.00 22.59  ? 99  PRO A CG  1 
ATOM   766   C  CD  . PRO A 1 99  ? -20.350 32.957  -29.032 1.00 20.68  ? 99  PRO A CD  1 
ATOM   767   N  N   . LYS A 1 100 ? -24.539 34.473  -28.745 1.00 25.52  ? 100 LYS A N   1 
ATOM   768   C  CA  . LYS A 1 100 ? -25.137 35.252  -27.670 1.00 30.62  ? 100 LYS A CA  1 
ATOM   769   C  C   . LYS A 1 100 ? -24.628 34.694  -26.344 1.00 28.45  ? 100 LYS A C   1 
ATOM   770   O  O   . LYS A 1 100 ? -24.562 33.473  -26.171 1.00 27.67  ? 100 LYS A O   1 
ATOM   771   C  CB  . LYS A 1 100 ? -26.658 35.159  -27.726 1.00 30.47  ? 100 LYS A CB  1 
ATOM   772   C  CG  . LYS A 1 100 ? -27.227 35.246  -29.105 1.00 32.19  ? 100 LYS A CG  1 
ATOM   773   C  CD  . LYS A 1 100 ? -28.735 35.215  -29.018 1.00 44.33  ? 100 LYS A CD  1 
ATOM   774   C  CE  . LYS A 1 100 ? -29.383 35.379  -30.385 1.00 48.69  ? 100 LYS A CE  1 
ATOM   775   N  NZ  . LYS A 1 100 ? -30.871 35.466  -30.269 1.00 52.28  ? 100 LYS A NZ  1 
ATOM   776   N  N   . TYR A 1 101 ? -24.224 35.573  -25.424 1.00 21.91  ? 101 TYR A N   1 
ATOM   777   C  CA  . TYR A 1 101 ? -23.577 35.090  -24.212 1.00 26.87  ? 101 TYR A CA  1 
ATOM   778   C  C   . TYR A 1 101 ? -23.786 36.067  -23.061 1.00 26.56  ? 101 TYR A C   1 
ATOM   779   O  O   . TYR A 1 101 ? -24.078 37.248  -23.262 1.00 25.24  ? 101 TYR A O   1 
ATOM   780   C  CB  . TYR A 1 101 ? -22.072 34.835  -24.424 1.00 22.33  ? 101 TYR A CB  1 
ATOM   781   C  CG  . TYR A 1 101 ? -21.261 36.098  -24.525 1.00 25.54  ? 101 TYR A CG  1 
ATOM   782   C  CD1 . TYR A 1 101 ? -21.111 36.742  -25.748 1.00 22.82  ? 101 TYR A CD1 1 
ATOM   783   C  CD2 . TYR A 1 101 ? -20.667 36.672  -23.395 1.00 23.53  ? 101 TYR A CD2 1 
ATOM   784   C  CE1 . TYR A 1 101 ? -20.383 37.905  -25.863 1.00 26.82  ? 101 TYR A CE1 1 
ATOM   785   C  CE2 . TYR A 1 101 ? -19.931 37.855  -23.507 1.00 24.46  ? 101 TYR A CE2 1 
ATOM   786   C  CZ  . TYR A 1 101 ? -19.807 38.452  -24.746 1.00 28.06  ? 101 TYR A CZ  1 
ATOM   787   O  OH  . TYR A 1 101 ? -19.095 39.595  -24.885 1.00 30.34  ? 101 TYR A OH  1 
ATOM   788   N  N   . LYS A 1 102 ? -23.642 35.541  -21.845 1.00 23.32  ? 102 LYS A N   1 
ATOM   789   C  CA  . LYS A 1 102 ? -23.591 36.326  -20.623 1.00 25.20  ? 102 LYS A CA  1 
ATOM   790   C  C   . LYS A 1 102 ? -22.464 35.790  -19.753 1.00 25.99  ? 102 LYS A C   1 
ATOM   791   O  O   . LYS A 1 102 ? -22.046 34.638  -19.888 1.00 24.82  ? 102 LYS A O   1 
ATOM   792   C  CB  . LYS A 1 102 ? -24.877 36.231  -19.801 1.00 30.49  ? 102 LYS A CB  1 
ATOM   793   C  CG  . LYS A 1 102 ? -26.149 36.619  -20.489 1.00 38.28  ? 102 LYS A CG  1 
ATOM   794   C  CD  . LYS A 1 102 ? -27.302 35.708  -20.033 1.00 42.10  ? 102 LYS A CD  1 
ATOM   795   C  CE  . LYS A 1 102 ? -27.140 35.233  -18.578 1.00 43.19  ? 102 LYS A CE  1 
ATOM   796   N  NZ  . LYS A 1 102 ? -28.096 34.134  -18.243 1.00 38.32  ? 102 LYS A NZ  1 
ATOM   797   N  N   . PHE A 1 103 ? -21.995 36.633  -18.834 1.00 25.40  ? 103 PHE A N   1 
ATOM   798   C  CA  . PHE A 1 103 ? -21.134 36.204  -17.738 1.00 23.46  ? 103 PHE A CA  1 
ATOM   799   C  C   . PHE A 1 103 ? -21.992 36.119  -16.489 1.00 25.65  ? 103 PHE A C   1 
ATOM   800   O  O   . PHE A 1 103 ? -22.577 37.122  -16.069 1.00 24.80  ? 103 PHE A O   1 
ATOM   801   C  CB  . PHE A 1 103 ? -19.975 37.179  -17.493 1.00 21.08  ? 103 PHE A CB  1 
ATOM   802   C  CG  . PHE A 1 103 ? -18.960 37.221  -18.604 1.00 21.05  ? 103 PHE A CG  1 
ATOM   803   C  CD1 . PHE A 1 103 ? -18.969 36.267  -19.603 1.00 18.41  ? 103 PHE A CD1 1 
ATOM   804   C  CD2 . PHE A 1 103 ? -17.974 38.201  -18.624 1.00 21.38  ? 103 PHE A CD2 1 
ATOM   805   C  CE1 . PHE A 1 103 ? -18.036 36.301  -20.609 1.00 20.04  ? 103 PHE A CE1 1 
ATOM   806   C  CE2 . PHE A 1 103 ? -17.019 38.228  -19.631 1.00 16.88  ? 103 PHE A CE2 1 
ATOM   807   C  CZ  . PHE A 1 103 ? -17.058 37.287  -20.623 1.00 17.83  ? 103 PHE A CZ  1 
ATOM   808   N  N   . VAL A 1 104 ? -22.040 34.944  -15.874 1.00 24.22  ? 104 VAL A N   1 
ATOM   809   C  CA  . VAL A 1 104 ? -22.782 34.787  -14.635 1.00 21.90  ? 104 VAL A CA  1 
ATOM   810   C  C   . VAL A 1 104 ? -21.872 34.138  -13.610 1.00 22.32  ? 104 VAL A C   1 
ATOM   811   O  O   . VAL A 1 104 ? -20.871 33.493  -13.932 1.00 24.45  ? 104 VAL A O   1 
ATOM   812   C  CB  . VAL A 1 104 ? -24.077 33.977  -14.805 1.00 26.81  ? 104 VAL A CB  1 
ATOM   813   C  CG1 . VAL A 1 104 ? -24.964 34.626  -15.866 1.00 24.21  ? 104 VAL A CG1 1 
ATOM   814   C  CG2 . VAL A 1 104 ? -23.753 32.516  -15.127 1.00 27.71  ? 104 VAL A CG2 1 
ATOM   815   N  N   . ARG A 1 105 ? -22.222 34.346  -12.360 1.00 24.50  ? 105 ARG A N   1 
ATOM   816   C  CA  . ARG A 1 105 ? -21.544 33.733  -11.237 1.00 24.76  ? 105 ARG A CA  1 
ATOM   817   C  C   . ARG A 1 105 ? -22.457 32.644  -10.695 1.00 26.55  ? 105 ARG A C   1 
ATOM   818   O  O   . ARG A 1 105 ? -23.604 32.923  -10.339 1.00 36.79  ? 105 ARG A O   1 
ATOM   819   C  CB  . ARG A 1 105 ? -21.223 34.792  -10.183 1.00 27.00  ? 105 ARG A CB  1 
ATOM   820   C  CG  . ARG A 1 105 ? -20.266 34.331  -9.138  1.00 33.24  ? 105 ARG A CG  1 
ATOM   821   C  CD  . ARG A 1 105 ? -19.456 35.460  -8.576  1.00 32.34  ? 105 ARG A CD  1 
ATOM   822   N  NE  . ARG A 1 105 ? -18.660 34.968  -7.457  1.00 35.52  ? 105 ARG A NE  1 
ATOM   823   C  CZ  . ARG A 1 105 ? -17.366 34.687  -7.511  1.00 30.86  ? 105 ARG A CZ  1 
ATOM   824   N  NH1 . ARG A 1 105 ? -16.658 34.890  -8.608  1.00 27.89  ? 105 ARG A NH1 1 
ATOM   825   N  NH2 . ARG A 1 105 ? -16.769 34.189  -6.435  1.00 29.42  ? 105 ARG A NH2 1 
ATOM   826   N  N   . ILE A 1 106 ? -21.997 31.399  -10.724 1.00 24.06  ? 106 ILE A N   1 
ATOM   827   C  CA  . ILE A 1 106 ? -22.807 30.306  -10.199 1.00 26.08  ? 106 ILE A CA  1 
ATOM   828   C  C   . ILE A 1 106 ? -22.640 30.213  -8.697  1.00 26.91  ? 106 ILE A C   1 
ATOM   829   O  O   . ILE A 1 106 ? -21.605 30.575  -8.135  1.00 26.75  ? 106 ILE A O   1 
ATOM   830   C  CB  . ILE A 1 106 ? -22.429 28.958  -10.826 1.00 28.67  ? 106 ILE A CB  1 
ATOM   831   C  CG1 . ILE A 1 106 ? -20.924 28.806  -10.745 1.00 24.95  ? 106 ILE A CG1 1 
ATOM   832   C  CG2 . ILE A 1 106 ? -23.047 28.768  -12.198 1.00 29.10  ? 106 ILE A CG2 1 
ATOM   833   C  CD1 . ILE A 1 106 ? -20.507 27.452  -10.981 1.00 31.25  ? 106 ILE A CD1 1 
ATOM   834   N  N   . GLN A 1 107 ? -23.642 29.663  -8.064  1.00 31.26  ? 107 GLN A N   1 
ATOM   835   C  CA  . GLN A 1 107 ? -23.747 29.399  -6.650  1.00 25.54  ? 107 GLN A CA  1 
ATOM   836   C  C   . GLN A 1 107 ? -23.452 27.930  -6.387  1.00 31.85  ? 107 GLN A C   1 
ATOM   837   O  O   . GLN A 1 107 ? -23.634 27.089  -7.276  1.00 30.89  ? 107 GLN A O   1 
ATOM   838   C  CB  . GLN A 1 107 ? -25.144 29.780  -6.159  1.00 33.64  ? 107 GLN A CB  1 
ATOM   839   C  CG  . GLN A 1 107 ? -25.386 31.310  -6.287  1.00 43.46  ? 107 GLN A CG  1 
ATOM   840   C  CD  . GLN A 1 107 ? -24.421 32.203  -5.464  1.00 47.36  ? 107 GLN A CD  1 
ATOM   841   O  OE1 . GLN A 1 107 ? -24.357 32.115  -4.231  1.00 50.07  ? 107 GLN A OE1 1 
ATOM   842   N  NE2 . GLN A 1 107 ? -23.638 33.031  -6.163  1.00 41.97  ? 107 GLN A NE2 1 
ATOM   843   N  N   . PRO A 1 108 ? -22.968 27.585  -5.170  1.00 28.67  ? 108 PRO A N   1 
ATOM   844   C  CA  . PRO A 1 108 ? -22.724 26.199  -4.819  1.00 28.80  ? 108 PRO A CA  1 
ATOM   845   C  C   . PRO A 1 108 ? -23.957 25.307  -4.987  1.00 30.24  ? 108 PRO A C   1 
ATOM   846   O  O   . PRO A 1 108 ? -25.020 25.679  -4.561  1.00 22.56  ? 108 PRO A O   1 
ATOM   847   C  CB  . PRO A 1 108 ? -22.310 26.280  -3.354  1.00 30.80  ? 108 PRO A CB  1 
ATOM   848   C  CG  . PRO A 1 108 ? -21.650 27.617  -3.251  1.00 31.64  ? 108 PRO A CG  1 
ATOM   849   C  CD  . PRO A 1 108 ? -22.564 28.488  -4.078  1.00 29.23  ? 108 PRO A CD  1 
ATOM   850   N  N   . GLY A 1 109 ? -23.750 24.140  -5.592  1.00 24.78  ? 109 GLY A N   1 
ATOM   851   C  CA  . GLY A 1 109 ? -24.854 23.244  -5.864  1.00 26.17  ? 109 GLY A CA  1 
ATOM   852   C  C   . GLY A 1 109 ? -25.428 23.338  -7.260  1.00 22.28  ? 109 GLY A C   1 
ATOM   853   O  O   . GLY A 1 109 ? -26.169 22.442  -7.659  1.00 25.65  ? 109 GLY A O   1 
ATOM   854   N  N   . GLN A 1 110 ? -25.113 24.387  -8.014  1.00 25.78  ? 110 GLN A N   1 
ATOM   855   C  CA  . GLN A 1 110 ? -25.496 24.442  -9.415  1.00 23.77  ? 110 GLN A CA  1 
ATOM   856   C  C   . GLN A 1 110 ? -24.513 23.646  -10.262 1.00 21.69  ? 110 GLN A C   1 
ATOM   857   O  O   . GLN A 1 110 ? -23.354 23.452  -9.900  1.00 20.92  ? 110 GLN A O   1 
ATOM   858   C  CB  . GLN A 1 110 ? -25.548 25.884  -9.925  1.00 21.35  ? 110 GLN A CB  1 
ATOM   859   C  CG  . GLN A 1 110 ? -26.438 26.813  -9.134  1.00 28.40  ? 110 GLN A CG  1 
ATOM   860   C  CD  . GLN A 1 110 ? -26.842 28.053  -9.931  1.00 43.36  ? 110 GLN A CD  1 
ATOM   861   O  OE1 . GLN A 1 110 ? -26.343 29.171  -9.691  1.00 41.08  ? 110 GLN A OE1 1 
ATOM   862   N  NE2 . GLN A 1 110 ? -27.754 27.858  -10.899 1.00 45.86  ? 110 GLN A NE2 1 
ATOM   863   N  N   . THR A 1 111 ? -24.985 23.210  -11.421 1.00 20.34  ? 111 THR A N   1 
ATOM   864   C  CA  . THR A 1 111 ? -24.186 22.441  -12.356 1.00 22.99  ? 111 THR A CA  1 
ATOM   865   C  C   . THR A 1 111 ? -23.852 23.270  -13.589 1.00 22.34  ? 111 THR A C   1 
ATOM   866   O  O   . THR A 1 111 ? -24.496 24.283  -13.870 1.00 21.58  ? 111 THR A O   1 
ATOM   867   C  CB  . THR A 1 111 ? -24.943 21.183  -12.784 1.00 20.36  ? 111 THR A CB  1 
ATOM   868   O  OG1 . THR A 1 111 ? -26.232 21.581  -13.263 1.00 21.03  ? 111 THR A OG1 1 
ATOM   869   C  CG2 . THR A 1 111 ? -25.093 20.208  -11.621 1.00 22.57  ? 111 THR A CG2 1 
ATOM   870   N  N   . PHE A 1 112 ? -22.876 22.773  -14.358 1.00 20.46  ? 112 PHE A N   1 
ATOM   871   C  CA  . PHE A 1 112 ? -22.498 23.344  -15.645 1.00 18.31  ? 112 PHE A CA  1 
ATOM   872   C  C   . PHE A 1 112 ? -21.647 22.323  -16.389 1.00 21.69  ? 112 PHE A C   1 
ATOM   873   O  O   . PHE A 1 112 ? -21.124 21.378  -15.794 1.00 21.12  ? 112 PHE A O   1 
ATOM   874   C  CB  . PHE A 1 112 ? -21.749 24.689  -15.493 1.00 18.66  ? 112 PHE A CB  1 
ATOM   875   C  CG  . PHE A 1 112 ? -20.518 24.623  -14.615 1.00 16.63  ? 112 PHE A CG  1 
ATOM   876   C  CD1 . PHE A 1 112 ? -20.604 24.846  -13.246 1.00 23.75  ? 112 PHE A CD1 1 
ATOM   877   C  CD2 . PHE A 1 112 ? -19.283 24.349  -15.148 1.00 16.11  ? 112 PHE A CD2 1 
ATOM   878   C  CE1 . PHE A 1 112 ? -19.473 24.785  -12.439 1.00 21.51  ? 112 PHE A CE1 1 
ATOM   879   C  CE2 . PHE A 1 112 ? -18.169 24.281  -14.353 1.00 17.13  ? 112 PHE A CE2 1 
ATOM   880   C  CZ  . PHE A 1 112 ? -18.264 24.497  -12.989 1.00 22.58  ? 112 PHE A CZ  1 
ATOM   881   N  N   . SER A 1 113 ? -21.518 22.520  -17.704 1.00 20.75  ? 113 SER A N   1 
ATOM   882   C  CA  . SER A 1 113 ? -20.655 21.685  -18.522 1.00 21.62  ? 113 SER A CA  1 
ATOM   883   C  C   . SER A 1 113 ? -19.291 22.325  -18.659 1.00 18.91  ? 113 SER A C   1 
ATOM   884   O  O   . SER A 1 113 ? -19.162 23.547  -18.682 1.00 19.54  ? 113 SER A O   1 
ATOM   885   C  CB  . SER A 1 113 ? -21.225 21.450  -19.921 1.00 23.76  ? 113 SER A CB  1 
ATOM   886   O  OG  . SER A 1 113 ? -22.534 20.970  -19.865 1.00 20.19  ? 113 SER A OG  1 
ATOM   887   N  N   . VAL A 1 114 ? -18.273 21.482  -18.788 1.00 21.16  ? 114 VAL A N   1 
ATOM   888   C  CA  . VAL A 1 114 ? -16.896 21.928  -18.934 1.00 20.51  ? 114 VAL A CA  1 
ATOM   889   C  C   . VAL A 1 114 ? -16.423 21.488  -20.316 1.00 22.69  ? 114 VAL A C   1 
ATOM   890   O  O   . VAL A 1 114 ? -16.495 20.304  -20.661 1.00 24.78  ? 114 VAL A O   1 
ATOM   891   C  CB  . VAL A 1 114 ? -15.995 21.359  -17.824 1.00 18.80  ? 114 VAL A CB  1 
ATOM   892   C  CG1 . VAL A 1 114 ? -14.550 21.752  -18.026 1.00 18.91  ? 114 VAL A CG1 1 
ATOM   893   C  CG2 . VAL A 1 114 ? -16.462 21.804  -16.472 1.00 18.71  ? 114 VAL A CG2 1 
ATOM   894   N  N   . LEU A 1 115 ? -15.949 22.434  -21.110 1.00 24.64  ? 115 LEU A N   1 
ATOM   895   C  CA  . LEU A 1 115 ? -15.285 22.103  -22.365 1.00 23.00  ? 115 LEU A CA  1 
ATOM   896   C  C   . LEU A 1 115 ? -13.787 22.173  -22.100 1.00 23.79  ? 115 LEU A C   1 
ATOM   897   O  O   . LEU A 1 115 ? -13.198 23.255  -22.100 1.00 24.32  ? 115 LEU A O   1 
ATOM   898   C  CB  . LEU A 1 115 ? -15.702 23.044  -23.487 1.00 16.50  ? 115 LEU A CB  1 
ATOM   899   C  CG  . LEU A 1 115 ? -14.992 22.626  -24.766 1.00 22.40  ? 115 LEU A CG  1 
ATOM   900   C  CD1 . LEU A 1 115 ? -15.550 21.259  -25.294 1.00 20.13  ? 115 LEU A CD1 1 
ATOM   901   C  CD2 . LEU A 1 115 ? -15.069 23.732  -25.812 1.00 21.75  ? 115 LEU A CD2 1 
ATOM   902   N  N   . ALA A 1 116 ? -13.174 21.018  -21.826 1.00 22.40  ? 116 ALA A N   1 
ATOM   903   C  CA  . ALA A 1 116 ? -11.750 20.974  -21.524 1.00 21.45  ? 116 ALA A CA  1 
ATOM   904   C  C   . ALA A 1 116 ? -10.933 21.094  -22.816 1.00 27.60  ? 116 ALA A C   1 
ATOM   905   O  O   . ALA A 1 116 ? -11.182 20.362  -23.787 1.00 27.50  ? 116 ALA A O   1 
ATOM   906   C  CB  . ALA A 1 116 ? -11.409 19.692  -20.774 1.00 23.15  ? 116 ALA A CB  1 
ATOM   907   N  N   . CYS A 1 117 ? -9.977  22.032  -22.832 1.00 20.72  ? 117 CYS A N   1 
ATOM   908   C  CA  . CYS A 1 117 ? -9.200  22.353  -24.022 1.00 25.28  ? 117 CYS A CA  1 
ATOM   909   C  C   . CYS A 1 117 ? -7.709  22.302  -23.719 1.00 25.73  ? 117 CYS A C   1 
ATOM   910   O  O   . CYS A 1 117 ? -7.279  22.472  -22.580 1.00 27.11  ? 117 CYS A O   1 
ATOM   911   C  CB  . CYS A 1 117 ? -9.548  23.744  -24.571 1.00 26.02  ? 117 CYS A CB  1 
ATOM   912   S  SG  . CYS A 1 117 ? -11.227 23.908  -25.189 1.00 30.19  ? 117 CYS A SG  1 
ATOM   913   N  N   . TYR A 1 118 ? -6.921  22.051  -24.757 1.00 25.96  ? 118 TYR A N   1 
ATOM   914   C  CA  . TYR A 1 118 ? -5.469  22.076  -24.676 1.00 25.75  ? 118 TYR A CA  1 
ATOM   915   C  C   . TYR A 1 118 ? -4.972  22.668  -25.981 1.00 27.56  ? 118 TYR A C   1 
ATOM   916   O  O   . TYR A 1 118 ? -5.456  22.290  -27.050 1.00 29.42  ? 118 TYR A O   1 
ATOM   917   C  CB  . TYR A 1 118 ? -4.878  20.674  -24.440 1.00 30.89  ? 118 TYR A CB  1 
ATOM   918   C  CG  . TYR A 1 118 ? -5.368  20.010  -23.170 1.00 30.33  ? 118 TYR A CG  1 
ATOM   919   C  CD1 . TYR A 1 118 ? -4.713  20.211  -21.957 1.00 22.70  ? 118 TYR A CD1 1 
ATOM   920   C  CD2 . TYR A 1 118 ? -6.527  19.230  -23.174 1.00 31.49  ? 118 TYR A CD2 1 
ATOM   921   C  CE1 . TYR A 1 118 ? -5.182  19.638  -20.802 1.00 25.81  ? 118 TYR A CE1 1 
ATOM   922   C  CE2 . TYR A 1 118 ? -7.006  18.646  -22.008 1.00 27.65  ? 118 TYR A CE2 1 
ATOM   923   C  CZ  . TYR A 1 118 ? -6.336  18.859  -20.832 1.00 26.49  ? 118 TYR A CZ  1 
ATOM   924   O  OH  . TYR A 1 118 ? -6.817  18.286  -19.682 1.00 29.24  ? 118 TYR A OH  1 
ATOM   925   N  N   . ASN A 1 119 ? -4.081  23.659  -25.886 1.00 28.17  ? 119 ASN A N   1 
ATOM   926   C  CA  . ASN A 1 119 ? -3.529  24.334  -27.063 1.00 28.01  ? 119 ASN A CA  1 
ATOM   927   C  C   . ASN A 1 119 ? -4.640  24.945  -27.920 1.00 24.79  ? 119 ASN A C   1 
ATOM   928   O  O   . ASN A 1 119 ? -4.567  24.965  -29.148 1.00 23.22  ? 119 ASN A O   1 
ATOM   929   C  CB  . ASN A 1 119 ? -2.675  23.373  -27.891 1.00 26.94  ? 119 ASN A CB  1 
ATOM   930   C  CG  . ASN A 1 119 ? -1.758  22.529  -27.032 1.00 33.00  ? 119 ASN A CG  1 
ATOM   931   O  OD1 . ASN A 1 119 ? -1.928  21.322  -26.930 1.00 37.72  ? 119 ASN A OD1 1 
ATOM   932   N  ND2 . ASN A 1 119 ? -0.778  23.164  -26.413 1.00 38.35  ? 119 ASN A ND2 1 
ATOM   933   N  N   . GLY A 1 120 ? -5.670  25.469  -27.267 1.00 23.66  ? 120 GLY A N   1 
ATOM   934   C  CA  . GLY A 1 120 ? -6.791  26.044  -27.990 1.00 24.25  ? 120 GLY A CA  1 
ATOM   935   C  C   . GLY A 1 120 ? -7.698  25.092  -28.763 1.00 27.70  ? 120 GLY A C   1 
ATOM   936   O  O   . GLY A 1 120 ? -8.504  25.567  -29.562 1.00 31.44  ? 120 GLY A O   1 
ATOM   937   N  N   . SER A 1 121 ? -7.635  23.771  -28.564 1.00 26.93  ? 121 SER A N   1 
ATOM   938   C  CA  . SER A 1 121 ? -8.683  23.025  -29.260 1.00 32.87  ? 121 SER A CA  1 
ATOM   939   C  C   . SER A 1 121 ? -9.435  22.089  -28.321 1.00 29.71  ? 121 SER A C   1 
ATOM   940   O  O   . SER A 1 121 ? -8.851  21.486  -27.408 1.00 27.11  ? 121 SER A O   1 
ATOM   941   C  CB  . SER A 1 121 ? -8.136  22.223  -30.450 1.00 35.75  ? 121 SER A CB  1 
ATOM   942   O  OG  . SER A 1 121 ? -6.983  21.503  -30.116 1.00 37.69  ? 121 SER A OG  1 
ATOM   943   N  N   . PRO A 1 122 ? -10.733 21.931  -28.546 1.00 34.68  ? 122 PRO A N   1 
ATOM   944   C  CA  . PRO A 1 122 ? -11.564 21.213  -27.572 1.00 29.04  ? 122 PRO A CA  1 
ATOM   945   C  C   . PRO A 1 122 ? -11.247 19.729  -27.562 1.00 32.66  ? 122 PRO A C   1 
ATOM   946   O  O   . PRO A 1 122 ? -11.018 19.109  -28.601 1.00 45.32  ? 122 PRO A O   1 
ATOM   947   C  CB  . PRO A 1 122 ? -12.990 21.492  -28.058 1.00 29.15  ? 122 PRO A CB  1 
ATOM   948   C  CG  . PRO A 1 122 ? -12.866 22.872  -28.731 1.00 30.66  ? 122 PRO A CG  1 
ATOM   949   C  CD  . PRO A 1 122 ? -11.539 22.780  -29.452 1.00 33.18  ? 122 PRO A CD  1 
ATOM   950   N  N   . SER A 1 123 ? -11.223 19.169  -26.363 1.00 33.14  ? 123 SER A N   1 
ATOM   951   C  CA  . SER A 1 123 ? -10.857 17.781  -26.117 1.00 38.39  ? 123 SER A CA  1 
ATOM   952   C  C   . SER A 1 123 ? -12.022 16.908  -25.659 1.00 35.98  ? 123 SER A C   1 
ATOM   953   O  O   . SER A 1 123 ? -12.131 15.745  -26.074 1.00 33.38  ? 123 SER A O   1 
ATOM   954   C  CB  . SER A 1 123 ? -9.728  17.757  -25.081 1.00 35.92  ? 123 SER A CB  1 
ATOM   955   O  OG  . SER A 1 123 ? -9.287  16.450  -24.806 1.00 52.49  ? 123 SER A OG  1 
ATOM   956   N  N   . GLY A 1 124 ? -12.897 17.431  -24.811 1.00 26.69  ? 124 GLY A N   1 
ATOM   957   C  CA  . GLY A 1 124 ? -14.003 16.651  -24.304 1.00 21.87  ? 124 GLY A CA  1 
ATOM   958   C  C   . GLY A 1 124 ? -14.903 17.525  -23.472 1.00 26.39  ? 124 GLY A C   1 
ATOM   959   O  O   . GLY A 1 124 ? -14.515 18.611  -23.022 1.00 32.77  ? 124 GLY A O   1 
ATOM   960   N  N   . VAL A 1 125 ? -16.102 17.040  -23.253 1.00 24.67  ? 125 VAL A N   1 
ATOM   961   C  CA  . VAL A 1 125 ? -17.098 17.825  -22.545 1.00 24.36  ? 125 VAL A CA  1 
ATOM   962   C  C   . VAL A 1 125 ? -17.714 16.949  -21.451 1.00 26.24  ? 125 VAL A C   1 
ATOM   963   O  O   . VAL A 1 125 ? -17.928 15.746  -21.648 1.00 23.30  ? 125 VAL A O   1 
ATOM   964   C  CB  . VAL A 1 125 ? -18.120 18.401  -23.558 1.00 21.99  ? 125 VAL A CB  1 
ATOM   965   C  CG1 . VAL A 1 125 ? -18.924 17.311  -24.178 1.00 24.75  ? 125 VAL A CG1 1 
ATOM   966   C  CG2 . VAL A 1 125 ? -18.988 19.526  -22.961 1.00 22.82  ? 125 VAL A CG2 1 
ATOM   967   N  N   . TYR A 1 126 ? -17.895 17.526  -20.262 1.00 21.87  ? 126 TYR A N   1 
ATOM   968   C  CA  . TYR A 1 126 ? -18.442 16.777  -19.139 1.00 26.29  ? 126 TYR A CA  1 
ATOM   969   C  C   . TYR A 1 126 ? -19.136 17.748  -18.196 1.00 28.61  ? 126 TYR A C   1 
ATOM   970   O  O   . TYR A 1 126 ? -18.839 18.947  -18.183 1.00 23.52  ? 126 TYR A O   1 
ATOM   971   C  CB  . TYR A 1 126 ? -17.355 15.963  -18.393 1.00 22.75  ? 126 TYR A CB  1 
ATOM   972   C  CG  . TYR A 1 126 ? -16.173 16.775  -17.904 1.00 27.06  ? 126 TYR A CG  1 
ATOM   973   C  CD1 . TYR A 1 126 ? -15.073 17.018  -18.727 1.00 23.57  ? 126 TYR A CD1 1 
ATOM   974   C  CD2 . TYR A 1 126 ? -16.156 17.319  -16.615 1.00 28.47  ? 126 TYR A CD2 1 
ATOM   975   C  CE1 . TYR A 1 126 ? -14.000 17.778  -18.282 1.00 22.39  ? 126 TYR A CE1 1 
ATOM   976   C  CE2 . TYR A 1 126 ? -15.075 18.093  -16.166 1.00 22.25  ? 126 TYR A CE2 1 
ATOM   977   C  CZ  . TYR A 1 126 ? -14.006 18.314  -17.003 1.00 23.29  ? 126 TYR A CZ  1 
ATOM   978   O  OH  . TYR A 1 126 ? -12.927 19.060  -16.562 1.00 20.04  ? 126 TYR A OH  1 
ATOM   979   N  N   . GLN A 1 127 ? -20.067 17.204  -17.404 1.00 28.49  ? 127 GLN A N   1 
ATOM   980   C  CA  . GLN A 1 127 ? -20.771 17.941  -16.365 1.00 25.22  ? 127 GLN A CA  1 
ATOM   981   C  C   . GLN A 1 127 ? -20.043 17.857  -15.043 1.00 27.32  ? 127 GLN A C   1 
ATOM   982   O  O   . GLN A 1 127 ? -19.477 16.825  -14.683 1.00 27.31  ? 127 GLN A O   1 
ATOM   983   C  CB  . GLN A 1 127 ? -22.169 17.390  -16.125 1.00 25.92  ? 127 GLN A CB  1 
ATOM   984   C  CG  . GLN A 1 127 ? -23.179 17.759  -17.127 1.00 31.98  ? 127 GLN A CG  1 
ATOM   985   C  CD  . GLN A 1 127 ? -23.661 19.175  -17.001 1.00 25.36  ? 127 GLN A CD  1 
ATOM   986   O  OE1 . GLN A 1 127 ? -23.327 20.015  -17.822 1.00 27.31  ? 127 GLN A OE1 1 
ATOM   987   N  NE2 . GLN A 1 127 ? -24.461 19.445  -15.987 1.00 24.49  ? 127 GLN A NE2 1 
ATOM   988   N  N   . CYS A 1 128 ? -20.131 18.937  -14.283 1.00 26.66  ? 128 CYS A N   1 
ATOM   989   C  CA  . CYS A 1 128 ? -19.819 18.887  -12.870 1.00 30.15  ? 128 CYS A CA  1 
ATOM   990   C  C   . CYS A 1 128 ? -20.579 20.002  -12.172 1.00 25.41  ? 128 CYS A C   1 
ATOM   991   O  O   . CYS A 1 128 ? -21.363 20.726  -12.792 1.00 24.23  ? 128 CYS A O   1 
ATOM   992   C  CB  . CYS A 1 128 ? -18.308 18.932  -12.623 1.00 35.24  ? 128 CYS A CB  1 
ATOM   993   S  SG  . CYS A 1 128 ? -17.442 20.105  -13.604 1.00 44.91  ? 128 CYS A SG  1 
ATOM   994   N  N   . ALA A 1 129 ? -20.401 20.069  -10.854 1.00 21.89  ? 129 ALA A N   1 
ATOM   995   C  CA  . ALA A 1 129 ? -21.166 20.959  -9.994  1.00 29.32  ? 129 ALA A CA  1 
ATOM   996   C  C   . ALA A 1 129 ? -20.222 21.772  -9.115  1.00 23.79  ? 129 ALA A C   1 
ATOM   997   O  O   . ALA A 1 129 ? -19.152 21.303  -8.723  1.00 22.16  ? 129 ALA A O   1 
ATOM   998   C  CB  . ALA A 1 129 ? -22.169 20.158  -9.138  1.00 20.43  ? 129 ALA A CB  1 
ATOM   999   N  N   . MET A 1 130 ? -20.633 22.991  -8.800  1.00 27.28  ? 130 MET A N   1 
ATOM   1000  C  CA  . MET A 1 130 ? -19.852 23.817  -7.855  1.00 25.40  ? 130 MET A CA  1 
ATOM   1001  C  C   . MET A 1 130 ? -20.111 23.279  -6.452  1.00 23.89  ? 130 MET A C   1 
ATOM   1002  O  O   . MET A 1 130 ? -21.260 23.249  -6.037  1.00 26.70  ? 130 MET A O   1 
ATOM   1003  C  CB  . MET A 1 130 ? -20.253 25.286  -7.931  1.00 25.19  ? 130 MET A CB  1 
ATOM   1004  C  CG  . MET A 1 130 ? -19.558 26.177  -6.921  1.00 27.76  ? 130 MET A CG  1 
ATOM   1005  S  SD  . MET A 1 130 ? -17.785 26.393  -7.201  1.00 29.93  ? 130 MET A SD  1 
ATOM   1006  C  CE  . MET A 1 130 ? -17.780 27.179  -8.809  1.00 23.93  ? 130 MET A CE  1 
ATOM   1007  N  N   . ARG A 1 131 ? -19.057 22.858  -5.780  1.00 22.77  ? 131 ARG A N   1 
ATOM   1008  C  CA  . ARG A 1 131 ? -19.183 22.291  -4.422  1.00 24.10  ? 131 ARG A CA  1 
ATOM   1009  C  C   . ARG A 1 131 ? -19.272 23.425  -3.395  1.00 26.53  ? 131 ARG A C   1 
ATOM   1010  O  O   . ARG A 1 131 ? -18.882 24.540  -3.722  1.00 23.00  ? 131 ARG A O   1 
ATOM   1011  C  CB  . ARG A 1 131 ? -18.040 21.311  -4.142  1.00 27.14  ? 131 ARG A CB  1 
ATOM   1012  C  CG  . ARG A 1 131 ? -17.735 20.331  -5.266  1.00 29.47  ? 131 ARG A CG  1 
ATOM   1013  C  CD  . ARG A 1 131 ? -18.796 19.286  -5.538  1.00 25.22  ? 131 ARG A CD  1 
ATOM   1014  N  NE  . ARG A 1 131 ? -19.353 18.684  -4.338  1.00 25.98  ? 131 ARG A NE  1 
ATOM   1015  C  CZ  . ARG A 1 131 ? -20.308 17.764  -4.336  1.00 29.78  ? 131 ARG A CZ  1 
ATOM   1016  N  NH1 . ARG A 1 131 ? -20.810 17.329  -5.476  1.00 20.14  ? 131 ARG A NH1 1 
ATOM   1017  N  NH2 . ARG A 1 131 ? -20.753 17.276  -3.194  1.00 30.88  ? 131 ARG A NH2 1 
ATOM   1018  N  N   . HIS A 1 132 ? -19.794 23.125  -2.208  1.00 23.02  ? 132 HIS A N   1 
ATOM   1019  C  CA  . HIS A 1 132 ? -19.993 24.146  -1.145  1.00 28.72  ? 132 HIS A CA  1 
ATOM   1020  C  C   . HIS A 1 132 ? -18.635 24.621  -0.607  1.00 28.51  ? 132 HIS A C   1 
ATOM   1021  O  O   . HIS A 1 132 ? -18.628 25.626  0.100   1.00 29.97  ? 132 HIS A O   1 
ATOM   1022  C  CB  . HIS A 1 132 ? -20.978 23.620  -0.091  1.00 27.45  ? 132 HIS A CB  1 
ATOM   1023  C  CG  . HIS A 1 132 ? -22.403 23.604  -0.527  1.00 23.85  ? 132 HIS A CG  1 
ATOM   1024  N  ND1 . HIS A 1 132 ? -22.973 22.513  -1.138  1.00 32.61  ? 132 HIS A ND1 1 
ATOM   1025  C  CD2 . HIS A 1 132 ? -23.373 24.532  -0.436  1.00 18.72  ? 132 HIS A CD2 1 
ATOM   1026  C  CE1 . HIS A 1 132 ? -24.232 22.774  -1.412  1.00 24.36  ? 132 HIS A CE1 1 
ATOM   1027  N  NE2 . HIS A 1 132 ? -24.500 24.001  -0.992  1.00 22.90  ? 132 HIS A NE2 1 
ATOM   1028  N  N   . ASN A 1 133 ? -17.543 23.923  -0.936  1.00 26.04  ? 133 ASN A N   1 
ATOM   1029  C  CA  . ASN A 1 133 ? -16.172 24.381  -0.587  1.00 22.22  ? 133 ASN A CA  1 
ATOM   1030  C  C   . ASN A 1 133 ? -15.612 25.141  -1.798  1.00 27.29  ? 133 ASN A C   1 
ATOM   1031  O  O   . ASN A 1 133 ? -14.395 25.329  -1.851  1.00 26.50  ? 133 ASN A O   1 
ATOM   1032  C  CB  . ASN A 1 133 ? -15.295 23.225  -0.128  1.00 26.06  ? 133 ASN A CB  1 
ATOM   1033  C  CG  . ASN A 1 133 ? -15.086 22.158  -1.180  1.00 23.15  ? 133 ASN A CG  1 
ATOM   1034  O  OD1 . ASN A 1 133 ? -15.587 22.259  -2.293  1.00 17.91  ? 133 ASN A OD1 1 
ATOM   1035  N  ND2 . ASN A 1 133 ? -14.339 21.130  -0.829  1.00 24.62  ? 133 ASN A ND2 1 
ATOM   1036  N  N   . PHE A 1 134 ? -16.475 25.504  -2.749  1.00 27.02  ? 134 PHE A N   1 
ATOM   1037  C  CA  . PHE A 1 134 ? -16.113 26.310  -3.953  1.00 24.92  ? 134 PHE A CA  1 
ATOM   1038  C  C   . PHE A 1 134 ? -15.104 25.594  -4.853  1.00 24.67  ? 134 PHE A C   1 
ATOM   1039  O  O   . PHE A 1 134 ? -14.340 26.279  -5.511  1.00 22.55  ? 134 PHE A O   1 
ATOM   1040  C  CB  . PHE A 1 134 ? -15.726 27.737  -3.550  1.00 26.37  ? 134 PHE A CB  1 
ATOM   1041  C  CG  . PHE A 1 134 ? -16.780 28.464  -2.762  1.00 25.97  ? 134 PHE A CG  1 
ATOM   1042  C  CD1 . PHE A 1 134 ? -17.776 29.176  -3.405  1.00 27.28  ? 134 PHE A CD1 1 
ATOM   1043  C  CD2 . PHE A 1 134 ? -16.780 28.429  -1.379  1.00 28.54  ? 134 PHE A CD2 1 
ATOM   1044  C  CE1 . PHE A 1 134 ? -18.751 29.843  -2.682  1.00 30.29  ? 134 PHE A CE1 1 
ATOM   1045  C  CE2 . PHE A 1 134 ? -17.755 29.097  -0.657  1.00 29.91  ? 134 PHE A CE2 1 
ATOM   1046  C  CZ  . PHE A 1 134 ? -18.738 29.801  -1.310  1.00 30.84  ? 134 PHE A CZ  1 
ATOM   1047  N  N   . THR A 1 135 ? -15.116 24.267  -4.866  1.00 23.31  ? 135 THR A N   1 
ATOM   1048  C  CA  . THR A 1 135 ? -14.294 23.522  -5.800  1.00 22.83  ? 135 THR A CA  1 
ATOM   1049  C  C   . THR A 1 135 ? -15.215 22.799  -6.759  1.00 19.11  ? 135 THR A C   1 
ATOM   1050  O  O   . THR A 1 135 ? -16.430 22.794  -6.593  1.00 22.68  ? 135 THR A O   1 
ATOM   1051  C  CB  . THR A 1 135 ? -13.377 22.523  -5.069  1.00 27.82  ? 135 THR A CB  1 
ATOM   1052  O  OG1 . THR A 1 135 ? -14.167 21.598  -4.303  1.00 26.37  ? 135 THR A OG1 1 
ATOM   1053  C  CG2 . THR A 1 135 ? -12.469 23.252  -4.134  1.00 25.08  ? 135 THR A CG2 1 
ATOM   1054  N  N   . ILE A 1 136 ? -14.625 22.197  -7.778  1.00 24.20  ? 136 ILE A N   1 
ATOM   1055  C  CA  . ILE A 1 136 ? -15.343 21.289  -8.653  1.00 24.64  ? 136 ILE A CA  1 
ATOM   1056  C  C   . ILE A 1 136 ? -14.463 20.068  -8.808  1.00 22.17  ? 136 ILE A C   1 
ATOM   1057  O  O   . ILE A 1 136 ? -13.257 20.112  -8.577  1.00 22.56  ? 136 ILE A O   1 
ATOM   1058  C  CB  . ILE A 1 136 ? -15.677 21.905  -10.025 1.00 26.16  ? 136 ILE A CB  1 
ATOM   1059  C  CG1 . ILE A 1 136 ? -14.396 22.165  -10.822 1.00 28.92  ? 136 ILE A CG1 1 
ATOM   1060  C  CG2 . ILE A 1 136 ? -16.432 23.214  -9.845  1.00 26.75  ? 136 ILE A CG2 1 
ATOM   1061  C  CD1 . ILE A 1 136 ? -14.651 22.473  -12.273 1.00 27.39  ? 136 ILE A CD1 1 
ATOM   1062  N  N   . LYS A 1 137 ? -15.089 18.964  -9.162  1.00 26.24  ? 137 LYS A N   1 
ATOM   1063  C  CA  . LYS A 1 137 ? -14.387 17.708  -9.390  1.00 30.06  ? 137 LYS A CA  1 
ATOM   1064  C  C   . LYS A 1 137 ? -14.366 17.464  -10.897 1.00 24.00  ? 137 LYS A C   1 
ATOM   1065  O  O   . LYS A 1 137 ? -15.267 16.836  -11.454 1.00 28.65  ? 137 LYS A O   1 
ATOM   1066  C  CB  . LYS A 1 137 ? -15.055 16.604  -8.613  1.00 27.08  ? 137 LYS A CB  1 
ATOM   1067  C  CG  . LYS A 1 137 ? -15.101 16.908  -7.121  1.00 27.00  ? 137 LYS A CG  1 
ATOM   1068  C  CD  . LYS A 1 137 ? -15.993 15.898  -6.416  1.00 39.22  ? 137 LYS A CD  1 
ATOM   1069  C  CE  . LYS A 1 137 ? -15.878 15.975  -4.914  1.00 39.54  ? 137 LYS A CE  1 
ATOM   1070  N  NZ  . LYS A 1 137 ? -16.857 15.013  -4.318  1.00 47.53  ? 137 LYS A NZ  1 
ATOM   1071  N  N   . GLY A 1 138 ? -13.336 17.990  -11.557 1.00 20.33  ? 138 GLY A N   1 
ATOM   1072  C  CA  . GLY A 1 138 ? -13.195 17.902  -12.988 1.00 24.10  ? 138 GLY A CA  1 
ATOM   1073  C  C   . GLY A 1 138 ? -12.079 16.963  -13.402 1.00 25.84  ? 138 GLY A C   1 
ATOM   1074  O  O   . GLY A 1 138 ? -11.633 16.104  -12.630 1.00 26.12  ? 138 GLY A O   1 
ATOM   1075  N  N   . SER A 1 139 ? -11.645 17.107  -14.655 1.00 18.89  ? 139 SER A N   1 
ATOM   1076  C  CA  . SER A 1 139 ? -10.539 16.327  -15.218 1.00 23.30  ? 139 SER A CA  1 
ATOM   1077  C  C   . SER A 1 139 ? -9.692  17.283  -16.058 1.00 20.86  ? 139 SER A C   1 
ATOM   1078  O  O   . SER A 1 139 ? -10.040 17.585  -17.203 1.00 25.05  ? 139 SER A O   1 
ATOM   1079  C  CB  . SER A 1 139 ? -11.052 15.153  -16.044 1.00 19.65  ? 139 SER A CB  1 
ATOM   1080  O  OG  . SER A 1 139 ? -10.042 14.634  -16.888 1.00 21.25  ? 139 SER A OG  1 
ATOM   1081  N  N   . PHE A 1 140 ? -8.576  17.740  -15.493 1.00 21.89  ? 140 PHE A N   1 
ATOM   1082  C  CA  . PHE A 1 140 ? -7.804  18.838  -16.058 1.00 25.88  ? 140 PHE A CA  1 
ATOM   1083  C  C   . PHE A 1 140 ? -6.336  18.468  -16.009 1.00 24.91  ? 140 PHE A C   1 
ATOM   1084  O  O   . PHE A 1 140 ? -5.848  18.056  -14.958 1.00 27.83  ? 140 PHE A O   1 
ATOM   1085  C  CB  . PHE A 1 140 ? -8.028  20.133  -15.256 1.00 24.27  ? 140 PHE A CB  1 
ATOM   1086  C  CG  . PHE A 1 140 ? -9.427  20.728  -15.382 1.00 27.74  ? 140 PHE A CG  1 
ATOM   1087  C  CD1 . PHE A 1 140 ? -9.821  21.397  -16.536 1.00 23.97  ? 140 PHE A CD1 1 
ATOM   1088  C  CD2 . PHE A 1 140 ? -10.339 20.624  -14.340 1.00 25.74  ? 140 PHE A CD2 1 
ATOM   1089  C  CE1 . PHE A 1 140 ? -11.076 21.962  -16.641 1.00 22.00  ? 140 PHE A CE1 1 
ATOM   1090  C  CE2 . PHE A 1 140 ? -11.626 21.184  -14.455 1.00 27.15  ? 140 PHE A CE2 1 
ATOM   1091  C  CZ  . PHE A 1 140 ? -11.975 21.858  -15.602 1.00 22.86  ? 140 PHE A CZ  1 
ATOM   1092  N  N   . LEU A 1 141 ? -5.631  18.611  -17.119 1.00 25.40  ? 141 LEU A N   1 
ATOM   1093  C  CA  . LEU A 1 141 ? -4.200  18.334  -17.153 1.00 30.68  ? 141 LEU A CA  1 
ATOM   1094  C  C   . LEU A 1 141 ? -3.430  19.622  -17.414 1.00 29.69  ? 141 LEU A C   1 
ATOM   1095  O  O   . LEU A 1 141 ? -4.012  20.695  -17.604 1.00 27.32  ? 141 LEU A O   1 
ATOM   1096  C  CB  . LEU A 1 141 ? -3.857  17.275  -18.210 1.00 30.24  ? 141 LEU A CB  1 
ATOM   1097  C  CG  . LEU A 1 141 ? -4.456  15.874  -18.053 1.00 30.16  ? 141 LEU A CG  1 
ATOM   1098  C  CD1 . LEU A 1 141 ? -4.230  15.042  -19.308 1.00 30.23  ? 141 LEU A CD1 1 
ATOM   1099  C  CD2 . LEU A 1 141 ? -3.847  15.214  -16.826 1.00 22.92  ? 141 LEU A CD2 1 
ATOM   1100  N  N   . ASN A 1 142 ? -2.102  19.498  -17.438 1.00 32.82  ? 142 ASN A N   1 
ATOM   1101  C  CA  . ASN A 1 142 ? -1.244  20.619  -17.814 1.00 34.37  ? 142 ASN A CA  1 
ATOM   1102  C  C   . ASN A 1 142 ? -1.695  21.184  -19.152 1.00 32.26  ? 142 ASN A C   1 
ATOM   1103  O  O   . ASN A 1 142 ? -1.897  20.445  -20.118 1.00 28.93  ? 142 ASN A O   1 
ATOM   1104  C  CB  . ASN A 1 142 ? 0.220   20.176  -17.913 1.00 34.76  ? 142 ASN A CB  1 
ATOM   1105  C  CG  . ASN A 1 142 ? 0.839   19.863  -16.567 1.00 35.36  ? 142 ASN A CG  1 
ATOM   1106  O  OD1 . ASN A 1 142 ? 0.414   20.390  -15.538 1.00 40.59  ? 142 ASN A OD1 1 
ATOM   1107  N  ND2 . ASN A 1 142 ? 1.889   19.031  -16.572 1.00 45.20  ? 142 ASN A ND2 1 
ATOM   1108  N  N   . GLY A 1 143 ? -1.906  22.489  -19.193 1.00 25.58  ? 143 GLY A N   1 
ATOM   1109  C  CA  . GLY A 1 143 ? -2.355  23.100  -20.419 1.00 27.39  ? 143 GLY A CA  1 
ATOM   1110  C  C   . GLY A 1 143 ? -3.852  23.244  -20.552 1.00 23.42  ? 143 GLY A C   1 
ATOM   1111  O  O   . GLY A 1 143 ? -4.313  23.744  -21.582 1.00 23.05  ? 143 GLY A O   1 
ATOM   1112  N  N   . SER A 1 144 ? -4.630  22.765  -19.578 1.00 18.93  ? 144 SER A N   1 
ATOM   1113  C  CA  . SER A 1 144 ? -6.072  22.937  -19.647 1.00 24.15  ? 144 SER A CA  1 
ATOM   1114  C  C   . SER A 1 144 ? -6.541  24.291  -19.133 1.00 19.59  ? 144 SER A C   1 
ATOM   1115  O  O   . SER A 1 144 ? -7.712  24.618  -19.332 1.00 20.32  ? 144 SER A O   1 
ATOM   1116  C  CB  . SER A 1 144 ? -6.810  21.828  -18.869 1.00 23.99  ? 144 SER A CB  1 
ATOM   1117  O  OG  . SER A 1 144 ? -6.448  21.827  -17.507 1.00 22.48  ? 144 SER A OG  1 
ATOM   1118  N  N   . CYS A 1 145 ? -5.673  25.074  -18.484 1.00 21.79  ? 145 CYS A N   1 
ATOM   1119  C  CA  . CYS A 1 145 ? -6.082  26.388  -17.988 1.00 23.36  ? 145 CYS A CA  1 
ATOM   1120  C  C   . CYS A 1 145 ? -6.636  27.217  -19.125 1.00 20.15  ? 145 CYS A C   1 
ATOM   1121  O  O   . CYS A 1 145 ? -6.181  27.106  -20.263 1.00 20.46  ? 145 CYS A O   1 
ATOM   1122  C  CB  . CYS A 1 145 ? -4.917  27.138  -17.336 1.00 21.85  ? 145 CYS A CB  1 
ATOM   1123  S  SG  . CYS A 1 145 ? -4.442  26.440  -15.769 1.00 23.41  ? 145 CYS A SG  1 
ATOM   1124  N  N   . GLY A 1 146 ? -7.643  28.035  -18.805 1.00 22.04  ? 146 GLY A N   1 
ATOM   1125  C  CA  . GLY A 1 146 ? -8.412  28.762  -19.781 1.00 17.39  ? 146 GLY A CA  1 
ATOM   1126  C  C   . GLY A 1 146 ? -9.639  28.035  -20.286 1.00 24.22  ? 146 GLY A C   1 
ATOM   1127  O  O   . GLY A 1 146 ? -10.458 28.652  -20.986 1.00 23.36  ? 146 GLY A O   1 
ATOM   1128  N  N   . SER A 1 147 ? -9.796  26.745  -19.960 1.00 19.95  ? 147 SER A N   1 
ATOM   1129  C  CA  . SER A 1 147 ? -11.057 26.068  -20.220 1.00 19.13  ? 147 SER A CA  1 
ATOM   1130  C  C   . SER A 1 147 ? -12.197 26.674  -19.407 1.00 16.41  ? 147 SER A C   1 
ATOM   1131  O  O   . SER A 1 147 ? -12.026 27.121  -18.269 1.00 18.77  ? 147 SER A O   1 
ATOM   1132  C  CB  . SER A 1 147 ? -10.926 24.574  -19.947 1.00 21.61  ? 147 SER A CB  1 
ATOM   1133  O  OG  . SER A 1 147 ? -9.925  24.023  -20.798 1.00 21.83  ? 147 SER A OG  1 
ATOM   1134  N  N   . VAL A 1 148 ? -13.373 26.685  -20.005 1.00 15.72  ? 148 VAL A N   1 
ATOM   1135  C  CA  . VAL A 1 148 ? -14.492 27.397  -19.417 1.00 20.08  ? 148 VAL A CA  1 
ATOM   1136  C  C   . VAL A 1 148 ? -15.625 26.429  -19.116 1.00 18.62  ? 148 VAL A C   1 
ATOM   1137  O  O   . VAL A 1 148 ? -15.786 25.399  -19.777 1.00 22.15  ? 148 VAL A O   1 
ATOM   1138  C  CB  . VAL A 1 148 ? -14.986 28.552  -20.327 1.00 15.77  ? 148 VAL A CB  1 
ATOM   1139  C  CG1 . VAL A 1 148 ? -13.875 29.577  -20.525 1.00 15.79  ? 148 VAL A CG1 1 
ATOM   1140  C  CG2 . VAL A 1 148 ? -15.480 28.026  -21.634 1.00 11.73  ? 148 VAL A CG2 1 
ATOM   1141  N  N   . GLY A 1 149 ? -16.441 26.796  -18.130 1.00 18.24  ? 149 GLY A N   1 
ATOM   1142  C  CA  . GLY A 1 149 ? -17.661 26.076  -17.809 1.00 18.33  ? 149 GLY A CA  1 
ATOM   1143  C  C   . GLY A 1 149 ? -18.837 26.929  -18.239 1.00 19.51  ? 149 GLY A C   1 
ATOM   1144  O  O   . GLY A 1 149 ? -18.728 28.162  -18.298 1.00 18.48  ? 149 GLY A O   1 
ATOM   1145  N  N   . PHE A 1 150 ? -19.951 26.270  -18.586 1.00 19.61  ? 150 PHE A N   1 
ATOM   1146  C  CA  . PHE A 1 150 ? -21.047 26.994  -19.221 1.00 22.32  ? 150 PHE A CA  1 
ATOM   1147  C  C   . PHE A 1 150 ? -22.365 26.239  -19.085 1.00 22.65  ? 150 PHE A C   1 
ATOM   1148  O  O   . PHE A 1 150 ? -22.403 25.009  -18.952 1.00 22.89  ? 150 PHE A O   1 
ATOM   1149  C  CB  . PHE A 1 150 ? -20.765 27.257  -20.713 1.00 19.78  ? 150 PHE A CB  1 
ATOM   1150  C  CG  . PHE A 1 150 ? -20.623 26.006  -21.540 1.00 21.56  ? 150 PHE A CG  1 
ATOM   1151  C  CD1 . PHE A 1 150 ? -19.423 25.333  -21.606 1.00 21.48  ? 150 PHE A CD1 1 
ATOM   1152  C  CD2 . PHE A 1 150 ? -21.714 25.491  -22.243 1.00 20.93  ? 150 PHE A CD2 1 
ATOM   1153  C  CE1 . PHE A 1 150 ? -19.302 24.142  -22.381 1.00 22.31  ? 150 PHE A CE1 1 
ATOM   1154  C  CE2 . PHE A 1 150 ? -21.606 24.330  -23.000 1.00 19.96  ? 150 PHE A CE2 1 
ATOM   1155  C  CZ  . PHE A 1 150 ? -20.380 23.653  -23.069 1.00 18.82  ? 150 PHE A CZ  1 
ATOM   1156  N  N   . ASN A 1 151 ? -23.446 27.014  -19.148 1.00 17.66  ? 151 ASN A N   1 
ATOM   1157  C  CA  . ASN A 1 151 ? -24.807 26.536  -19.322 1.00 23.26  ? 151 ASN A CA  1 
ATOM   1158  C  C   . ASN A 1 151 ? -25.387 27.208  -20.560 1.00 27.35  ? 151 ASN A C   1 
ATOM   1159  O  O   . ASN A 1 151 ? -24.940 28.283  -20.984 1.00 25.29  ? 151 ASN A O   1 
ATOM   1160  C  CB  . ASN A 1 151 ? -25.706 26.864  -18.113 1.00 21.75  ? 151 ASN A CB  1 
ATOM   1161  C  CG  . ASN A 1 151 ? -25.413 26.004  -16.894 1.00 24.57  ? 151 ASN A CG  1 
ATOM   1162  O  OD1 . ASN A 1 151 ? -24.617 26.383  -16.028 1.00 23.94  ? 151 ASN A OD1 1 
ATOM   1163  N  ND2 . ASN A 1 151 ? -26.104 24.882  -16.783 1.00 24.69  ? 151 ASN A ND2 1 
ATOM   1164  N  N   . ILE A 1 152 ? -26.413 26.580  -21.126 1.00 26.01  ? 152 ILE A N   1 
ATOM   1165  C  CA  . ILE A 1 152 ? -27.112 27.129  -22.279 1.00 28.69  ? 152 ILE A CA  1 
ATOM   1166  C  C   . ILE A 1 152 ? -28.592 27.234  -21.949 1.00 29.11  ? 152 ILE A C   1 
ATOM   1167  O  O   . ILE A 1 152 ? -29.181 26.292  -21.409 1.00 35.71  ? 152 ILE A O   1 
ATOM   1168  C  CB  . ILE A 1 152 ? -26.891 26.284  -23.544 1.00 26.36  ? 152 ILE A CB  1 
ATOM   1169  C  CG1 . ILE A 1 152 ? -25.408 25.920  -23.681 1.00 25.44  ? 152 ILE A CG1 1 
ATOM   1170  C  CG2 . ILE A 1 152 ? -27.328 27.080  -24.766 1.00 30.81  ? 152 ILE A CG2 1 
ATOM   1171  C  CD1 . ILE A 1 152 ? -25.027 25.307  -25.027 1.00 30.75  ? 152 ILE A CD1 1 
ATOM   1172  N  N   . ASP A 1 153 ? -29.176 28.396  -22.215 1.00 32.58  ? 153 ASP A N   1 
ATOM   1173  C  CA  . ASP A 1 153 ? -30.619 28.573  -22.112 1.00 38.23  ? 153 ASP A CA  1 
ATOM   1174  C  C   . ASP A 1 153 ? -31.141 28.996  -23.475 1.00 40.44  ? 153 ASP A C   1 
ATOM   1175  O  O   . ASP A 1 153 ? -30.892 30.125  -23.916 1.00 39.25  ? 153 ASP A O   1 
ATOM   1176  C  CB  . ASP A 1 153 ? -31.004 29.602  -21.060 1.00 39.86  ? 153 ASP A CB  1 
ATOM   1177  C  CG  . ASP A 1 153 ? -32.512 29.694  -20.892 1.00 51.49  ? 153 ASP A CG  1 
ATOM   1178  O  OD1 . ASP A 1 153 ? -33.120 28.696  -20.420 1.00 55.67  ? 153 ASP A OD1 1 
ATOM   1179  O  OD2 . ASP A 1 153 ? -33.089 30.740  -21.274 1.00 44.71  ? 153 ASP A OD2 1 
ATOM   1180  N  N   . TYR A 1 154 ? -31.860 28.087  -24.135 1.00 34.56  ? 154 TYR A N   1 
ATOM   1181  C  CA  . TYR A 1 154 ? -32.353 28.317  -25.486 1.00 38.01  ? 154 TYR A CA  1 
ATOM   1182  C  C   . TYR A 1 154 ? -31.175 28.584  -26.422 1.00 41.10  ? 154 TYR A C   1 
ATOM   1183  O  O   . TYR A 1 154 ? -30.576 27.645  -26.958 1.00 38.94  ? 154 TYR A O   1 
ATOM   1184  C  CB  . TYR A 1 154 ? -33.374 29.454  -25.533 1.00 36.03  ? 154 TYR A CB  1 
ATOM   1185  C  CG  . TYR A 1 154 ? -34.219 29.424  -26.786 0.00 35.59  ? 154 TYR A CG  1 
ATOM   1186  C  CD1 . TYR A 1 154 ? -34.817 28.242  -27.205 0.00 34.61  ? 154 TYR A CD1 1 
ATOM   1187  C  CD2 . TYR A 1 154 ? -34.420 30.566  -27.549 0.00 35.50  ? 154 TYR A CD2 1 
ATOM   1188  C  CE1 . TYR A 1 154 ? -35.590 28.195  -28.345 0.00 33.77  ? 154 TYR A CE1 1 
ATOM   1189  C  CE2 . TYR A 1 154 ? -35.195 30.528  -28.696 0.00 34.60  ? 154 TYR A CE2 1 
ATOM   1190  C  CZ  . TYR A 1 154 ? -35.777 29.339  -29.088 0.00 33.45  ? 154 TYR A CZ  1 
ATOM   1191  O  OH  . TYR A 1 154 ? -36.549 29.293  -30.226 0.00 32.80  ? 154 TYR A OH  1 
ATOM   1192  N  N   . ASP A 1 155 ? -30.827 29.853  -26.632 1.00 33.93  ? 155 ASP A N   1 
ATOM   1193  C  CA  . ASP A 1 155 ? -29.726 30.198  -27.519 1.00 33.43  ? 155 ASP A CA  1 
ATOM   1194  C  C   . ASP A 1 155 ? -28.581 30.939  -26.838 1.00 36.96  ? 155 ASP A C   1 
ATOM   1195  O  O   . ASP A 1 155 ? -27.593 31.271  -27.511 1.00 31.36  ? 155 ASP A O   1 
ATOM   1196  C  CB  . ASP A 1 155 ? -30.245 31.074  -28.662 1.00 37.40  ? 155 ASP A CB  1 
ATOM   1197  C  CG  . ASP A 1 155 ? -31.043 32.265  -28.150 1.00 43.24  ? 155 ASP A CG  1 
ATOM   1198  O  OD1 . ASP A 1 155 ? -31.533 32.205  -26.994 1.00 43.01  ? 155 ASP A OD1 1 
ATOM   1199  O  OD2 . ASP A 1 155 ? -31.144 33.278  -28.881 1.00 47.41  ? 155 ASP A OD2 1 
ATOM   1200  N  N   . CYS A 1 156 ? -28.708 31.276  -25.556 1.00 34.64  ? 156 CYS A N   1 
ATOM   1201  C  CA  . CYS A 1 156 ? -27.722 32.094  -24.861 1.00 27.21  ? 156 CYS A CA  1 
ATOM   1202  C  C   . CYS A 1 156 ? -26.729 31.239  -24.074 1.00 30.05  ? 156 CYS A C   1 
ATOM   1203  O  O   . CYS A 1 156 ? -27.128 30.351  -23.302 1.00 26.28  ? 156 CYS A O   1 
ATOM   1204  C  CB  . CYS A 1 156 ? -28.407 33.076  -23.920 1.00 29.06  ? 156 CYS A CB  1 
ATOM   1205  S  SG  . CYS A 1 156 ? -27.189 34.170  -23.200 1.00 37.64  ? 156 CYS A SG  1 
ATOM   1206  N  N   . VAL A 1 157 ? -25.437 31.509  -24.258 1.00 23.73  ? 157 VAL A N   1 
ATOM   1207  C  CA  . VAL A 1 157 ? -24.403 30.822  -23.486 1.00 27.50  ? 157 VAL A CA  1 
ATOM   1208  C  C   . VAL A 1 157 ? -24.089 31.639  -22.239 1.00 28.29  ? 157 VAL A C   1 
ATOM   1209  O  O   . VAL A 1 157 ? -23.672 32.796  -22.341 1.00 21.90  ? 157 VAL A O   1 
ATOM   1210  C  CB  . VAL A 1 157 ? -23.135 30.590  -24.322 1.00 22.64  ? 157 VAL A CB  1 
ATOM   1211  C  CG1 . VAL A 1 157 ? -22.086 29.862  -23.468 1.00 18.42  ? 157 VAL A CG1 1 
ATOM   1212  C  CG2 . VAL A 1 157 ? -23.479 29.792  -25.588 1.00 18.36  ? 157 VAL A CG2 1 
ATOM   1213  N  N   . SER A 1 158 ? -24.253 31.020  -21.056 1.00 24.17  ? 158 SER A N   1 
ATOM   1214  C  CA  . SER A 1 158 ? -23.916 31.648  -19.778 1.00 19.78  ? 158 SER A CA  1 
ATOM   1215  C  C   . SER A 1 158 ? -22.567 31.111  -19.319 1.00 24.28  ? 158 SER A C   1 
ATOM   1216  O  O   . SER A 1 158 ? -22.469 29.970  -18.855 1.00 26.89  ? 158 SER A O   1 
ATOM   1217  C  CB  . SER A 1 158 ? -24.994 31.373  -18.741 1.00 23.32  ? 158 SER A CB  1 
ATOM   1218  O  OG  . SER A 1 158 ? -26.162 32.133  -18.998 1.00 28.98  ? 158 SER A OG  1 
ATOM   1219  N  N   . PHE A 1 159 ? -21.520 31.921  -19.467 1.00 21.50  ? 159 PHE A N   1 
ATOM   1220  C  CA  . PHE A 1 159 ? -20.190 31.524  -19.018 1.00 21.85  ? 159 PHE A CA  1 
ATOM   1221  C  C   . PHE A 1 159 ? -20.089 31.732  -17.513 1.00 20.33  ? 159 PHE A C   1 
ATOM   1222  O  O   . PHE A 1 159 ? -20.275 32.847  -17.025 1.00 25.94  ? 159 PHE A O   1 
ATOM   1223  C  CB  . PHE A 1 159 ? -19.100 32.312  -19.756 1.00 21.67  ? 159 PHE A CB  1 
ATOM   1224  C  CG  . PHE A 1 159 ? -19.037 32.011  -21.231 1.00 20.67  ? 159 PHE A CG  1 
ATOM   1225  C  CD1 . PHE A 1 159 ? -18.492 30.827  -21.683 1.00 16.84  ? 159 PHE A CD1 1 
ATOM   1226  C  CD2 . PHE A 1 159 ? -19.526 32.914  -22.164 1.00 21.79  ? 159 PHE A CD2 1 
ATOM   1227  C  CE1 . PHE A 1 159 ? -18.450 30.542  -23.023 1.00 19.75  ? 159 PHE A CE1 1 
ATOM   1228  C  CE2 . PHE A 1 159 ? -19.486 32.621  -23.508 1.00 16.47  ? 159 PHE A CE2 1 
ATOM   1229  C  CZ  . PHE A 1 159 ? -18.952 31.433  -23.934 1.00 16.80  ? 159 PHE A CZ  1 
ATOM   1230  N  N   . CYS A 1 160 ? -19.767 30.667  -16.778 1.00 22.08  ? 160 CYS A N   1 
ATOM   1231  C  CA  . CYS A 1 160 ? -19.702 30.746  -15.329 1.00 19.71  ? 160 CYS A CA  1 
ATOM   1232  C  C   . CYS A 1 160 ? -18.343 30.405  -14.739 1.00 20.14  ? 160 CYS A C   1 
ATOM   1233  O  O   . CYS A 1 160 ? -18.115 30.721  -13.564 1.00 19.80  ? 160 CYS A O   1 
ATOM   1234  C  CB  . CYS A 1 160 ? -20.765 29.836  -14.694 1.00 21.22  ? 160 CYS A CB  1 
ATOM   1235  S  SG  . CYS A 1 160 ? -20.634 28.065  -15.145 1.00 24.86  ? 160 CYS A SG  1 
ATOM   1236  N  N   . TYR A 1 161 ? -17.435 29.788  -15.498 1.00 16.82  ? 161 TYR A N   1 
ATOM   1237  C  CA  . TYR A 1 161 ? -16.207 29.274  -14.899 1.00 19.41  ? 161 TYR A CA  1 
ATOM   1238  C  C   . TYR A 1 161 ? -15.037 29.287  -15.871 1.00 17.53  ? 161 TYR A C   1 
ATOM   1239  O  O   . TYR A 1 161 ? -15.178 28.845  -17.009 1.00 19.71  ? 161 TYR A O   1 
ATOM   1240  C  CB  . TYR A 1 161 ? -16.417 27.843  -14.398 1.00 17.88  ? 161 TYR A CB  1 
ATOM   1241  C  CG  . TYR A 1 161 ? -15.189 27.203  -13.804 1.00 17.11  ? 161 TYR A CG  1 
ATOM   1242  C  CD1 . TYR A 1 161 ? -14.850 27.435  -12.475 1.00 19.20  ? 161 TYR A CD1 1 
ATOM   1243  C  CD2 . TYR A 1 161 ? -14.423 26.296  -14.531 1.00 18.42  ? 161 TYR A CD2 1 
ATOM   1244  C  CE1 . TYR A 1 161 ? -13.743 26.824  -11.887 1.00 19.61  ? 161 TYR A CE1 1 
ATOM   1245  C  CE2 . TYR A 1 161 ? -13.312 25.665  -13.952 1.00 20.09  ? 161 TYR A CE2 1 
ATOM   1246  C  CZ  . TYR A 1 161 ? -12.978 25.939  -12.625 1.00 20.24  ? 161 TYR A CZ  1 
ATOM   1247  O  OH  . TYR A 1 161 ? -11.883 25.348  -12.026 1.00 18.86  ? 161 TYR A OH  1 
ATOM   1248  N  N   . MET A 1 162 ? -13.859 29.685  -15.388 1.00 17.32  ? 162 MET A N   1 
ATOM   1249  C  CA  . MET A 1 162 ? -12.620 29.526  -16.149 1.00 20.63  ? 162 MET A CA  1 
ATOM   1250  C  C   . MET A 1 162 ? -11.580 28.828  -15.287 1.00 20.89  ? 162 MET A C   1 
ATOM   1251  O  O   . MET A 1 162 ? -11.419 29.166  -14.116 1.00 23.14  ? 162 MET A O   1 
ATOM   1252  C  CB  . MET A 1 162 ? -12.078 30.867  -16.654 1.00 17.61  ? 162 MET A CB  1 
ATOM   1253  C  CG  . MET A 1 162 ? -10.717 30.760  -17.320 1.00 18.62  ? 162 MET A CG  1 
ATOM   1254  S  SD  . MET A 1 162 ? -10.166 32.345  -18.033 1.00 26.18  ? 162 MET A SD  1 
ATOM   1255  C  CE  . MET A 1 162 ? -11.055 32.288  -19.603 1.00 19.94  ? 162 MET A CE  1 
ATOM   1256  N  N   . HIS A 1 163 ? -10.916 27.818  -15.838 1.00 22.36  ? 163 HIS A N   1 
ATOM   1257  C  CA  . HIS A 1 163 ? -10.069 26.978  -14.998 1.00 23.51  ? 163 HIS A CA  1 
ATOM   1258  C  C   . HIS A 1 163 ? -8.726  27.626  -14.712 1.00 19.24  ? 163 HIS A C   1 
ATOM   1259  O  O   . HIS A 1 163 ? -8.081  28.176  -15.610 1.00 22.53  ? 163 HIS A O   1 
ATOM   1260  C  CB  . HIS A 1 163 ? -9.821  25.605  -15.626 1.00 18.15  ? 163 HIS A CB  1 
ATOM   1261  C  CG  . HIS A 1 163 ? -9.029  24.699  -14.737 1.00 21.10  ? 163 HIS A CG  1 
ATOM   1262  N  ND1 . HIS A 1 163 ? -9.449  24.357  -13.466 1.00 21.30  ? 163 HIS A ND1 1 
ATOM   1263  C  CD2 . HIS A 1 163 ? -7.835  24.086  -14.916 1.00 19.39  ? 163 HIS A CD2 1 
ATOM   1264  C  CE1 . HIS A 1 163 ? -8.557  23.556  -12.910 1.00 21.16  ? 163 HIS A CE1 1 
ATOM   1265  N  NE2 . HIS A 1 163 ? -7.568  23.375  -13.768 1.00 21.11  ? 163 HIS A NE2 1 
ATOM   1266  N  N   . HIS A 1 164 ? -8.255  27.457  -13.474 1.00 22.16  ? 164 HIS A N   1 
ATOM   1267  C  CA  . HIS A 1 164 ? -6.987  28.033  -13.055 1.00 20.28  ? 164 HIS A CA  1 
ATOM   1268  C  C   . HIS A 1 164 ? -6.023  27.044  -12.414 1.00 22.69  ? 164 HIS A C   1 
ATOM   1269  O  O   . HIS A 1 164 ? -4.821  27.128  -12.678 1.00 25.13  ? 164 HIS A O   1 
ATOM   1270  C  CB  . HIS A 1 164 ? -7.222  29.200  -12.076 1.00 16.26  ? 164 HIS A CB  1 
ATOM   1271  C  CG  . HIS A 1 164 ? -7.553  30.489  -12.755 1.00 21.39  ? 164 HIS A CG  1 
ATOM   1272  N  ND1 . HIS A 1 164 ? -8.796  30.752  -13.298 1.00 23.08  ? 164 HIS A ND1 1 
ATOM   1273  C  CD2 . HIS A 1 164 ? -6.776  31.558  -13.058 1.00 23.24  ? 164 HIS A CD2 1 
ATOM   1274  C  CE1 . HIS A 1 164 ? -8.786  31.954  -13.851 1.00 26.24  ? 164 HIS A CE1 1 
ATOM   1275  N  NE2 . HIS A 1 164 ? -7.571  32.464  -13.722 1.00 25.37  ? 164 HIS A NE2 1 
ATOM   1276  N  N   . MET A 1 165 ? -6.497  26.139  -11.558 1.00 20.20  ? 165 MET A N   1 
ATOM   1277  C  CA  . MET A 1 165 ? -5.567  25.423  -10.695 1.00 20.51  ? 165 MET A CA  1 
ATOM   1278  C  C   . MET A 1 165 ? -6.186  24.145  -10.147 1.00 20.86  ? 165 MET A C   1 
ATOM   1279  O  O   . MET A 1 165 ? -7.407  23.983  -10.099 1.00 17.55  ? 165 MET A O   1 
ATOM   1280  C  CB  . MET A 1 165 ? -5.119  26.295  -9.522  1.00 19.54  ? 165 MET A CB  1 
ATOM   1281  C  CG  . MET A 1 165 ? -6.265  26.792  -8.716  1.00 24.45  ? 165 MET A CG  1 
ATOM   1282  S  SD  . MET A 1 165 ? -5.727  27.832  -7.342  1.00 39.53  ? 165 MET A SD  1 
ATOM   1283  C  CE  . MET A 1 165 ? -4.591  26.717  -6.505  1.00 32.65  ? 165 MET A CE  1 
ATOM   1284  N  N   . GLU A 1 166 ? -5.298  23.253  -9.716  1.00 27.51  ? 166 GLU A N   1 
ATOM   1285  C  CA  . GLU A 1 166 ? -5.624  22.030  -8.993  1.00 28.43  ? 166 GLU A CA  1 
ATOM   1286  C  C   . GLU A 1 166 ? -5.245  22.172  -7.522  1.00 28.40  ? 166 GLU A C   1 
ATOM   1287  O  O   . GLU A 1 166 ? -4.187  22.714  -7.198  1.00 26.96  ? 166 GLU A O   1 
ATOM   1288  C  CB  . GLU A 1 166 ? -4.902  20.837  -9.619  1.00 26.72  ? 166 GLU A CB  1 
ATOM   1289  C  CG  . GLU A 1 166 ? -5.071  19.554  -8.855  1.00 34.45  ? 166 GLU A CG  1 
ATOM   1290  C  CD  . GLU A 1 166 ? -4.799  18.322  -9.687  1.00 39.88  ? 166 GLU A CD  1 
ATOM   1291  O  OE1 . GLU A 1 166 ? -4.793  18.416  -10.942 1.00 33.87  ? 166 GLU A OE1 1 
ATOM   1292  O  OE2 . GLU A 1 166 ? -4.580  17.251  -9.069  1.00 45.37  ? 166 GLU A OE2 1 
ATOM   1293  N  N   . LEU A 1 167 ? -6.096  21.644  -6.648  1.00 30.22  ? 167 LEU A N   1 
ATOM   1294  C  CA  . LEU A 1 167 ? -6.022  21.691  -5.193  1.00 29.45  ? 167 LEU A CA  1 
ATOM   1295  C  C   . LEU A 1 167 ? -5.699  20.306  -4.594  1.00 35.12  ? 167 LEU A C   1 
ATOM   1296  O  O   . LEU A 1 167 ? -5.785  19.283  -5.284  1.00 35.38  ? 167 LEU A O   1 
ATOM   1297  C  CB  . LEU A 1 167 ? -7.346  22.225  -4.635  1.00 25.53  ? 167 LEU A CB  1 
ATOM   1298  C  CG  . LEU A 1 167 ? -7.590  23.715  -4.868  1.00 33.69  ? 167 LEU A CG  1 
ATOM   1299  C  CD1 . LEU A 1 167 ? -9.040  24.056  -4.590  1.00 31.73  ? 167 LEU A CD1 1 
ATOM   1300  C  CD2 . LEU A 1 167 ? -6.672  24.568  -4.004  1.00 27.70  ? 167 LEU A CD2 1 
ATOM   1301  N  N   . PRO A 1 168 ? -5.355  20.241  -3.291  1.00 31.79  ? 168 PRO A N   1 
ATOM   1302  C  CA  . PRO A 1 168 ? -4.793  18.990  -2.727  1.00 39.71  ? 168 PRO A CA  1 
ATOM   1303  C  C   . PRO A 1 168 ? -5.486  17.671  -3.040  1.00 40.32  ? 168 PRO A C   1 
ATOM   1304  O  O   . PRO A 1 168 ? -4.796  16.712  -3.403  1.00 42.91  ? 168 PRO A O   1 
ATOM   1305  C  CB  . PRO A 1 168 ? -4.805  19.279  -1.222  1.00 37.41  ? 168 PRO A CB  1 
ATOM   1306  C  CG  . PRO A 1 168 ? -4.530  20.760  -1.170  1.00 37.00  ? 168 PRO A CG  1 
ATOM   1307  C  CD  . PRO A 1 168 ? -5.270  21.350  -2.319  1.00 35.48  ? 168 PRO A CD  1 
ATOM   1308  N  N   . THR A 1 169 ? -6.800  17.574  -2.919  1.00 37.41  ? 169 THR A N   1 
ATOM   1309  C  CA  . THR A 1 169 ? -7.443  16.273  -3.095  1.00 37.44  ? 169 THR A CA  1 
ATOM   1310  C  C   . THR A 1 169 ? -7.695  15.905  -4.559  1.00 43.13  ? 169 THR A C   1 
ATOM   1311  O  O   . THR A 1 169 ? -8.580  15.081  -4.826  1.00 35.49  ? 169 THR A O   1 
ATOM   1312  C  CB  . THR A 1 169 ? -8.759  16.234  -2.323  1.00 42.81  ? 169 THR A CB  1 
ATOM   1313  O  OG1 . THR A 1 169 ? -9.595  17.306  -2.763  1.00 46.58  ? 169 THR A OG1 1 
ATOM   1314  C  CG2 . THR A 1 169 ? -8.502  16.400  -0.835  1.00 39.80  ? 169 THR A CG2 1 
ATOM   1315  N  N   . GLY A 1 170 ? -6.968  16.496  -5.508  1.00 39.17  ? 170 GLY A N   1 
ATOM   1316  C  CA  . GLY A 1 170 ? -7.258  16.262  -6.904  1.00 29.33  ? 170 GLY A CA  1 
ATOM   1317  C  C   . GLY A 1 170 ? -8.490  16.991  -7.386  1.00 29.72  ? 170 GLY A C   1 
ATOM   1318  O  O   . GLY A 1 170 ? -9.128  16.550  -8.342  1.00 32.11  ? 170 GLY A O   1 
ATOM   1319  N  N   . VAL A 1 171 ? -8.869  18.085  -6.733  1.00 32.73  ? 171 VAL A N   1 
ATOM   1320  C  CA  . VAL A 1 171 ? -10.000 18.887  -7.188  1.00 27.71  ? 171 VAL A CA  1 
ATOM   1321  C  C   . VAL A 1 171 ? -9.513  20.233  -7.708  1.00 26.52  ? 171 VAL A C   1 
ATOM   1322  O  O   . VAL A 1 171 ? -8.320  20.553  -7.644  1.00 23.71  ? 171 VAL A O   1 
ATOM   1323  C  CB  . VAL A 1 171 ? -11.060 19.051  -6.080  1.00 31.19  ? 171 VAL A CB  1 
ATOM   1324  C  CG1 . VAL A 1 171 ? -11.644 17.668  -5.689  1.00 27.00  ? 171 VAL A CG1 1 
ATOM   1325  C  CG2 . VAL A 1 171 ? -10.465 19.761  -4.858  1.00 23.68  ? 171 VAL A CG2 1 
ATOM   1326  N  N   . HIS A 1 172 ? -10.439 21.046  -8.207  1.00 29.80  ? 172 HIS A N   1 
ATOM   1327  C  CA  . HIS A 1 172 ? -10.082 22.136  -9.091  1.00 21.48  ? 172 HIS A CA  1 
ATOM   1328  C  C   . HIS A 1 172 ? -10.758 23.420  -8.656  1.00 25.12  ? 172 HIS A C   1 
ATOM   1329  O  O   . HIS A 1 172 ? -11.846 23.396  -8.077  1.00 23.35  ? 172 HIS A O   1 
ATOM   1330  C  CB  . HIS A 1 172 ? -10.465 21.772  -10.505 1.00 18.81  ? 172 HIS A CB  1 
ATOM   1331  C  CG  . HIS A 1 172 ? -9.795  20.524  -10.983 1.00 28.25  ? 172 HIS A CG  1 
ATOM   1332  N  ND1 . HIS A 1 172 ? -10.442 19.305  -11.049 1.00 23.65  ? 172 HIS A ND1 1 
ATOM   1333  C  CD2 . HIS A 1 172 ? -8.522  20.298  -11.384 1.00 25.11  ? 172 HIS A CD2 1 
ATOM   1334  C  CE1 . HIS A 1 172 ? -9.603  18.392  -11.498 1.00 25.17  ? 172 HIS A CE1 1 
ATOM   1335  N  NE2 . HIS A 1 172 ? -8.432  18.965  -11.706 1.00 26.69  ? 172 HIS A NE2 1 
ATOM   1336  N  N   . ALA A 1 173 ? -10.095 24.539  -8.972  1.00 17.43  ? 173 ALA A N   1 
ATOM   1337  C  CA  . ALA A 1 173 ? -10.501 25.873  -8.557  1.00 19.62  ? 173 ALA A CA  1 
ATOM   1338  C  C   . ALA A 1 173 ? -10.305 26.859  -9.707  1.00 21.66  ? 173 ALA A C   1 
ATOM   1339  O  O   . ALA A 1 173 ? -9.361  26.741  -10.501 1.00 15.69  ? 173 ALA A O   1 
ATOM   1340  C  CB  . ALA A 1 173 ? -9.708  26.334  -7.325  1.00 17.75  ? 173 ALA A CB  1 
ATOM   1341  N  N   . GLY A 1 174 ? -11.217 27.815  -9.799  1.00 18.23  ? 174 GLY A N   1 
ATOM   1342  C  CA  . GLY A 1 174 ? -11.142 28.789  -10.858 1.00 20.97  ? 174 GLY A CA  1 
ATOM   1343  C  C   . GLY A 1 174 ? -11.961 30.016  -10.530 1.00 20.08  ? 174 GLY A C   1 
ATOM   1344  O  O   . GLY A 1 174 ? -12.453 30.177  -9.409  1.00 17.27  ? 174 GLY A O   1 
ATOM   1345  N  N   . THR A 1 175 ? -12.118 30.867  -11.542 1.00 15.43  ? 175 THR A N   1 
ATOM   1346  C  CA  . THR A 1 175 ? -12.796 32.144  -11.419 1.00 18.19  ? 175 THR A CA  1 
ATOM   1347  C  C   . THR A 1 175 ? -14.041 32.172  -12.284 1.00 17.91  ? 175 THR A C   1 
ATOM   1348  O  O   . THR A 1 175 ? -14.228 31.350  -13.194 1.00 18.24  ? 175 THR A O   1 
ATOM   1349  C  CB  . THR A 1 175 ? -11.896 33.316  -11.856 1.00 23.28  ? 175 THR A CB  1 
ATOM   1350  O  OG1 . THR A 1 175 ? -11.624 33.198  -13.264 1.00 19.91  ? 175 THR A OG1 1 
ATOM   1351  C  CG2 . THR A 1 175 ? -10.607 33.342  -11.074 1.00 20.59  ? 175 THR A CG2 1 
ATOM   1352  N  N   . ASP A 1 176 ? -14.874 33.173  -12.017 1.00 16.89  ? 176 ASP A N   1 
ATOM   1353  C  CA  . ASP A 1 176 ? -15.850 33.573  -13.014 1.00 17.74  ? 176 ASP A CA  1 
ATOM   1354  C  C   . ASP A 1 176 ? -15.133 34.314  -14.136 1.00 18.06  ? 176 ASP A C   1 
ATOM   1355  O  O   . ASP A 1 176 ? -13.907 34.450  -14.144 1.00 19.13  ? 176 ASP A O   1 
ATOM   1356  C  CB  . ASP A 1 176 ? -16.952 34.426  -12.393 1.00 22.14  ? 176 ASP A CB  1 
ATOM   1357  C  CG  . ASP A 1 176 ? -16.439 35.731  -11.775 1.00 23.18  ? 176 ASP A CG  1 
ATOM   1358  O  OD1 . ASP A 1 176 ? -15.372 36.279  -12.170 1.00 21.92  ? 176 ASP A OD1 1 
ATOM   1359  O  OD2 . ASP A 1 176 ? -17.153 36.229  -10.886 1.00 28.05  ? 176 ASP A OD2 1 
ATOM   1360  N  N   . LEU A 1 177 ? -15.906 34.810  -15.096 1.00 20.72  ? 177 LEU A N   1 
ATOM   1361  C  CA  . LEU A 1 177 ? -15.313 35.436  -16.266 1.00 19.08  ? 177 LEU A CA  1 
ATOM   1362  C  C   . LEU A 1 177 ? -14.953 36.904  -16.039 1.00 21.75  ? 177 LEU A C   1 
ATOM   1363  O  O   . LEU A 1 177 ? -14.490 37.571  -16.971 1.00 22.08  ? 177 LEU A O   1 
ATOM   1364  C  CB  . LEU A 1 177 ? -16.244 35.268  -17.462 1.00 18.66  ? 177 LEU A CB  1 
ATOM   1365  C  CG  . LEU A 1 177 ? -15.924 34.010  -18.273 1.00 19.26  ? 177 LEU A CG  1 
ATOM   1366  C  CD1 . LEU A 1 177 ? -14.569 34.156  -18.906 1.00 16.46  ? 177 LEU A CD1 1 
ATOM   1367  C  CD2 . LEU A 1 177 ? -16.003 32.716  -17.413 1.00 20.04  ? 177 LEU A CD2 1 
ATOM   1368  N  N   . GLU A 1 178 ? -15.188 37.429  -14.843 1.00 24.58  ? 178 GLU A N   1 
ATOM   1369  C  CA  . GLU A 1 178 ? -14.599 38.694  -14.422 1.00 28.96  ? 178 GLU A CA  1 
ATOM   1370  C  C   . GLU A 1 178 ? -13.290 38.482  -13.676 1.00 24.87  ? 178 GLU A C   1 
ATOM   1371  O  O   . GLU A 1 178 ? -12.719 39.446  -13.160 1.00 25.88  ? 178 GLU A O   1 
ATOM   1372  C  CB  . GLU A 1 178 ? -15.558 39.474  -13.514 1.00 26.60  ? 178 GLU A CB  1 
ATOM   1373  C  CG  . GLU A 1 178 ? -17.046 39.467  -13.848 1.00 32.33  ? 178 GLU A CG  1 
ATOM   1374  C  CD  . GLU A 1 178 ? -17.570 40.818  -14.309 1.00 43.62  ? 178 GLU A CD  1 
ATOM   1375  O  OE1 . GLU A 1 178 ? -16.794 41.603  -14.884 1.00 53.43  ? 178 GLU A OE1 1 
ATOM   1376  O  OE2 . GLU A 1 178 ? -18.749 41.135  -14.038 1.00 48.51  ? 178 GLU A OE2 1 
ATOM   1377  N  N   . GLY A 1 179 ? -12.832 37.240  -13.553 1.00 21.53  ? 179 GLY A N   1 
ATOM   1378  C  CA  . GLY A 1 179 ? -11.575 36.974  -12.889 1.00 23.14  ? 179 GLY A CA  1 
ATOM   1379  C  C   . GLY A 1 179 ? -11.631 36.843  -11.383 1.00 22.52  ? 179 GLY A C   1 
ATOM   1380  O  O   . GLY A 1 179 ? -10.578 36.847  -10.744 1.00 24.74  ? 179 GLY A O   1 
ATOM   1381  N  N   . ASN A 1 180 ? -12.808 36.719  -10.786 1.00 20.89  ? 180 ASN A N   1 
ATOM   1382  C  CA  . ASN A 1 180 ? -12.920 36.582  -9.339  1.00 19.61  ? 180 ASN A CA  1 
ATOM   1383  C  C   . ASN A 1 180 ? -13.003 35.106  -8.974  1.00 19.05  ? 180 ASN A C   1 
ATOM   1384  O  O   . ASN A 1 180 ? -13.922 34.412  -9.411  1.00 16.50  ? 180 ASN A O   1 
ATOM   1385  C  CB  . ASN A 1 180 ? -14.146 37.346  -8.829  1.00 22.19  ? 180 ASN A CB  1 
ATOM   1386  C  CG  . ASN A 1 180 ? -14.106 38.824  -9.219  1.00 22.96  ? 180 ASN A CG  1 
ATOM   1387  O  OD1 . ASN A 1 180 ? -13.255 39.571  -8.745  1.00 19.08  ? 180 ASN A OD1 1 
ATOM   1388  N  ND2 . ASN A 1 180 ? -15.003 39.234  -10.107 1.00 22.39  ? 180 ASN A ND2 1 
ATOM   1389  N  N   . PHE A 1 181 ? -12.052 34.641  -8.158  1.00 22.25  ? 181 PHE A N   1 
ATOM   1390  C  CA  . PHE A 1 181 ? -12.030 33.247  -7.731  1.00 19.58  ? 181 PHE A CA  1 
ATOM   1391  C  C   . PHE A 1 181 ? -13.314 32.863  -7.026  1.00 18.92  ? 181 PHE A C   1 
ATOM   1392  O  O   . PHE A 1 181 ? -13.871 33.631  -6.245  1.00 22.24  ? 181 PHE A O   1 
ATOM   1393  C  CB  . PHE A 1 181 ? -10.841 32.989  -6.814  1.00 16.86  ? 181 PHE A CB  1 
ATOM   1394  C  CG  . PHE A 1 181 ? -9.667  32.411  -7.535  1.00 25.37  ? 181 PHE A CG  1 
ATOM   1395  C  CD1 . PHE A 1 181 ? -9.564  31.039  -7.726  1.00 20.75  ? 181 PHE A CD1 1 
ATOM   1396  C  CD2 . PHE A 1 181 ? -8.701  33.252  -8.114  1.00 23.03  ? 181 PHE A CD2 1 
ATOM   1397  C  CE1 . PHE A 1 181 ? -8.503  30.485  -8.427  1.00 18.97  ? 181 PHE A CE1 1 
ATOM   1398  C  CE2 . PHE A 1 181 ? -7.642  32.705  -8.832  1.00 22.13  ? 181 PHE A CE2 1 
ATOM   1399  C  CZ  . PHE A 1 181 ? -7.547  31.301  -8.977  1.00 24.07  ? 181 PHE A CZ  1 
ATOM   1400  N  N   . TYR A 1 182 ? -13.780 31.658  -7.292  1.00 18.78  ? 182 TYR A N   1 
ATOM   1401  C  CA  . TYR A 1 182 ? -14.747 31.040  -6.402  1.00 20.36  ? 182 TYR A CA  1 
ATOM   1402  C  C   . TYR A 1 182 ? -14.001 30.485  -5.186  1.00 23.89  ? 182 TYR A C   1 
ATOM   1403  O  O   . TYR A 1 182 ? -13.100 29.654  -5.340  1.00 21.75  ? 182 TYR A O   1 
ATOM   1404  C  CB  . TYR A 1 182 ? -15.485 29.933  -7.133  1.00 17.89  ? 182 TYR A CB  1 
ATOM   1405  C  CG  . TYR A 1 182 ? -16.386 30.375  -8.256  1.00 18.03  ? 182 TYR A CG  1 
ATOM   1406  C  CD1 . TYR A 1 182 ? -17.656 30.887  -7.993  1.00 21.95  ? 182 TYR A CD1 1 
ATOM   1407  C  CD2 . TYR A 1 182 ? -15.999 30.226  -9.582  1.00 14.48  ? 182 TYR A CD2 1 
ATOM   1408  C  CE1 . TYR A 1 182 ? -18.513 31.258  -9.035  1.00 21.96  ? 182 TYR A CE1 1 
ATOM   1409  C  CE2 . TYR A 1 182 ? -16.838 30.583  -10.626 1.00 15.92  ? 182 TYR A CE2 1 
ATOM   1410  C  CZ  . TYR A 1 182 ? -18.094 31.105  -10.352 1.00 19.04  ? 182 TYR A CZ  1 
ATOM   1411  O  OH  . TYR A 1 182 ? -18.942 31.467  -11.379 1.00 17.26  ? 182 TYR A OH  1 
ATOM   1412  N  N   . GLY A 1 183 ? -14.328 30.972  -3.983  1.00 22.08  ? 183 GLY A N   1 
ATOM   1413  C  CA  . GLY A 1 183 ? -13.753 30.420  -2.778  1.00 20.74  ? 183 GLY A CA  1 
ATOM   1414  C  C   . GLY A 1 183 ? -12.426 31.026  -2.379  1.00 23.68  ? 183 GLY A C   1 
ATOM   1415  O  O   . GLY A 1 183 ? -11.909 31.940  -3.030  1.00 27.29  ? 183 GLY A O   1 
ATOM   1416  N  N   . PRO A 1 184 ? -11.836 30.521  -1.296  1.00 22.78  ? 184 PRO A N   1 
ATOM   1417  C  CA  . PRO A 1 184 ? -10.641 31.125  -0.705  1.00 27.77  ? 184 PRO A CA  1 
ATOM   1418  C  C   . PRO A 1 184 ? -9.332  30.727  -1.388  1.00 29.40  ? 184 PRO A C   1 
ATOM   1419  O  O   . PRO A 1 184 ? -8.388  30.241  -0.751  1.00 24.21  ? 184 PRO A O   1 
ATOM   1420  C  CB  . PRO A 1 184 ? -10.685 30.592  0.739   1.00 28.49  ? 184 PRO A CB  1 
ATOM   1421  C  CG  . PRO A 1 184 ? -11.263 29.223  0.578   1.00 20.33  ? 184 PRO A CG  1 
ATOM   1422  C  CD  . PRO A 1 184 ? -12.238 29.298  -0.584  1.00 22.03  ? 184 PRO A CD  1 
ATOM   1423  N  N   . PHE A 1 185 ? -9.280  30.926  -2.707  1.00 25.78  ? 185 PHE A N   1 
ATOM   1424  C  CA  . PHE A 1 185 ? -8.138  30.506  -3.500  1.00 23.70  ? 185 PHE A CA  1 
ATOM   1425  C  C   . PHE A 1 185 ? -7.544  31.709  -4.210  1.00 26.32  ? 185 PHE A C   1 
ATOM   1426  O  O   . PHE A 1 185 ? -8.257  32.665  -4.534  1.00 21.96  ? 185 PHE A O   1 
ATOM   1427  C  CB  . PHE A 1 185 ? -8.568  29.422  -4.499  1.00 23.82  ? 185 PHE A CB  1 
ATOM   1428  C  CG  . PHE A 1 185 ? -9.344  28.322  -3.850  1.00 24.43  ? 185 PHE A CG  1 
ATOM   1429  C  CD1 . PHE A 1 185 ? -8.748  27.524  -2.871  1.00 25.78  ? 185 PHE A CD1 1 
ATOM   1430  C  CD2 . PHE A 1 185 ? -10.670 28.114  -4.161  1.00 21.67  ? 185 PHE A CD2 1 
ATOM   1431  C  CE1 . PHE A 1 185 ? -9.466  26.512  -2.222  1.00 27.02  ? 185 PHE A CE1 1 
ATOM   1432  C  CE2 . PHE A 1 185 ? -11.393 27.098  -3.537  1.00 28.69  ? 185 PHE A CE2 1 
ATOM   1433  C  CZ  . PHE A 1 185 ? -10.799 26.295  -2.559  1.00 21.97  ? 185 PHE A CZ  1 
ATOM   1434  N  N   . VAL A 1 186 ? -6.235  31.638  -4.470  1.00 22.05  ? 186 VAL A N   1 
ATOM   1435  C  CA  . VAL A 1 186 ? -5.511  32.683  -5.172  1.00 22.67  ? 186 VAL A CA  1 
ATOM   1436  C  C   . VAL A 1 186 ? -4.651  32.008  -6.227  1.00 26.76  ? 186 VAL A C   1 
ATOM   1437  O  O   . VAL A 1 186 ? -4.330  30.820  -6.130  1.00 26.81  ? 186 VAL A O   1 
ATOM   1438  C  CB  . VAL A 1 186 ? -4.641  33.557  -4.237  1.00 28.52  ? 186 VAL A CB  1 
ATOM   1439  C  CG1 . VAL A 1 186 ? -5.517  34.324  -3.240  1.00 22.80  ? 186 VAL A CG1 1 
ATOM   1440  C  CG2 . VAL A 1 186 ? -3.579  32.726  -3.535  1.00 30.31  ? 186 VAL A CG2 1 
ATOM   1441  N  N   . ASP A 1 187 ? -4.294  32.774  -7.260  1.00 23.13  ? 187 ASP A N   1 
ATOM   1442  C  CA  . ASP A 1 187 ? -3.494  32.226  -8.357  1.00 26.39  ? 187 ASP A CA  1 
ATOM   1443  C  C   . ASP A 1 187 ? -2.003  32.393  -8.045  1.00 31.71  ? 187 ASP A C   1 
ATOM   1444  O  O   . ASP A 1 187 ? -1.252  33.136  -8.682  1.00 22.13  ? 187 ASP A O   1 
ATOM   1445  C  CB  . ASP A 1 187 ? -3.896  32.852  -9.689  1.00 27.29  ? 187 ASP A CB  1 
ATOM   1446  C  CG  . ASP A 1 187 ? -3.915  34.364  -9.653  1.00 21.69  ? 187 ASP A CG  1 
ATOM   1447  O  OD1 . ASP A 1 187 ? -3.687  34.951  -8.573  1.00 28.32  ? 187 ASP A OD1 1 
ATOM   1448  O  OD2 . ASP A 1 187 ? -4.170  34.954  -10.715 1.00 18.89  ? 187 ASP A OD2 1 
ATOM   1449  N  N   . ARG A 1 188 ? -1.589  31.658  -7.015  1.00 33.65  ? 188 ARG A N   1 
ATOM   1450  C  CA  . ARG A 1 188 ? -0.198  31.554  -6.607  1.00 33.81  ? 188 ARG A CA  1 
ATOM   1451  C  C   . ARG A 1 188 ? 0.080   30.079  -6.357  1.00 30.07  ? 188 ARG A C   1 
ATOM   1452  O  O   . ARG A 1 188 ? -0.840  29.294  -6.160  1.00 31.12  ? 188 ARG A O   1 
ATOM   1453  C  CB  . ARG A 1 188 ? 0.096   32.416  -5.352  1.00 28.75  ? 188 ARG A CB  1 
ATOM   1454  C  CG  . ARG A 1 188 ? -0.384  33.871  -5.505  1.00 42.38  ? 188 ARG A CG  1 
ATOM   1455  C  CD  . ARG A 1 188 ? 0.275   34.906  -4.555  1.00 47.84  ? 188 ARG A CD  1 
ATOM   1456  N  NE  . ARG A 1 188 ? -0.239  34.940  -3.187  1.00 62.69  ? 188 ARG A NE  1 
ATOM   1457  C  CZ  . ARG A 1 188 ? -1.167  35.790  -2.759  1.00 54.27  ? 188 ARG A CZ  1 
ATOM   1458  N  NH1 . ARG A 1 188 ? -1.749  36.651  -3.580  1.00 57.48  ? 188 ARG A NH1 1 
ATOM   1459  N  NH2 . ARG A 1 188 ? -1.509  35.788  -1.473  1.00 50.24  ? 188 ARG A NH2 1 
ATOM   1460  N  N   . GLN A 1 189 ? 1.357   29.703  -6.375  1.00 35.12  ? 189 GLN A N   1 
ATOM   1461  C  CA  . GLN A 1 189 ? 1.781   28.328  -6.083  1.00 35.09  ? 189 GLN A CA  1 
ATOM   1462  C  C   . GLN A 1 189 ? 2.127   28.251  -4.598  1.00 33.54  ? 189 GLN A C   1 
ATOM   1463  O  O   . GLN A 1 189 ? 3.289   28.306  -4.191  1.00 37.88  ? 189 GLN A O   1 
ATOM   1464  C  CB  . GLN A 1 189 ? 2.956   27.942  -6.978  1.00 36.33  ? 189 GLN A CB  1 
ATOM   1465  C  CG  . GLN A 1 189 ? 3.491   26.538  -6.813  1.00 33.20  ? 189 GLN A CG  1 
ATOM   1466  C  CD  . GLN A 1 189 ? 4.414   26.140  -7.955  1.00 32.67  ? 189 GLN A CD  1 
ATOM   1467  O  OE1 . GLN A 1 189 ? 4.517   26.850  -8.953  1.00 33.36  ? 189 GLN A OE1 1 
ATOM   1468  N  NE2 . GLN A 1 189 ? 5.120   25.026  -7.795  1.00 30.23  ? 189 GLN A NE2 1 
ATOM   1469  N  N   . THR A 1 190 ? 1.078   28.188  -3.772  1.00 31.78  ? 190 THR A N   1 
ATOM   1470  C  CA  . THR A 1 190 ? 1.206   28.167  -2.321  1.00 34.72  ? 190 THR A CA  1 
ATOM   1471  C  C   . THR A 1 190 ? 0.288   27.114  -1.720  1.00 42.69  ? 190 THR A C   1 
ATOM   1472  O  O   . THR A 1 190 ? -0.603  26.575  -2.386  1.00 44.23  ? 190 THR A O   1 
ATOM   1473  C  CB  . THR A 1 190 ? 0.870   29.527  -1.708  1.00 36.59  ? 190 THR A CB  1 
ATOM   1474  O  OG1 . THR A 1 190 ? -0.504  29.818  -1.982  1.00 39.31  ? 190 THR A OG1 1 
ATOM   1475  C  CG2 . THR A 1 190 ? 1.762   30.635  -2.273  1.00 35.38  ? 190 THR A CG2 1 
ATOM   1476  N  N   . ALA A 1 191 ? 0.517   26.824  -0.436  1.00 42.41  ? 191 ALA A N   1 
ATOM   1477  C  CA  . ALA A 1 191 ? -0.300  25.849  0.279   1.00 41.46  ? 191 ALA A CA  1 
ATOM   1478  C  C   . ALA A 1 191 ? -1.691  26.438  0.490   1.00 36.65  ? 191 ALA A C   1 
ATOM   1479  O  O   . ALA A 1 191 ? -1.858  27.428  1.211   1.00 35.67  ? 191 ALA A O   1 
ATOM   1480  C  CB  . ALA A 1 191 ? 0.352   25.477  1.607   1.00 37.52  ? 191 ALA A CB  1 
ATOM   1481  N  N   . GLN A 1 192 ? -2.678  25.858  -0.180  1.00 30.52  ? 192 GLN A N   1 
ATOM   1482  C  CA  . GLN A 1 192 ? -4.069  26.257  -0.077  1.00 34.74  ? 192 GLN A CA  1 
ATOM   1483  C  C   . GLN A 1 192 ? -4.885  25.001  0.137   1.00 36.15  ? 192 GLN A C   1 
ATOM   1484  O  O   . GLN A 1 192 ? -4.602  23.965  -0.474  1.00 41.30  ? 192 GLN A O   1 
ATOM   1485  C  CB  . GLN A 1 192 ? -4.567  26.980  -1.344  1.00 35.71  ? 192 GLN A CB  1 
ATOM   1486  C  CG  . GLN A 1 192 ? -3.647  28.073  -1.867  1.00 30.07  ? 192 GLN A CG  1 
ATOM   1487  C  CD  . GLN A 1 192 ? -4.224  28.810  -3.062  1.00 31.36  ? 192 GLN A CD  1 
ATOM   1488  O  OE1 . GLN A 1 192 ? -5.329  29.349  -2.996  1.00 31.50  ? 192 GLN A OE1 1 
ATOM   1489  N  NE2 . GLN A 1 192 ? -3.467  28.853  -4.156  1.00 28.86  ? 192 GLN A NE2 1 
ATOM   1490  N  N   . ALA A 1 193 ? -5.876  25.077  1.012   1.00 35.95  ? 193 ALA A N   1 
ATOM   1491  C  CA  . ALA A 1 193 ? -6.735  23.935  1.272   1.00 35.83  ? 193 ALA A CA  1 
ATOM   1492  C  C   . ALA A 1 193 ? -8.157  24.264  0.848   1.00 33.24  ? 193 ALA A C   1 
ATOM   1493  O  O   . ALA A 1 193 ? -8.664  25.353  1.125   1.00 33.06  ? 193 ALA A O   1 
ATOM   1494  C  CB  . ALA A 1 193 ? -6.708  23.536  2.746   1.00 26.48  ? 193 ALA A CB  1 
ATOM   1495  N  N   . ALA A 1 194 ? -8.786  23.305  0.166   1.00 37.55  ? 194 ALA A N   1 
ATOM   1496  C  CA  . ALA A 1 194 ? -10.155 23.473  -0.304  1.00 26.50  ? 194 ALA A CA  1 
ATOM   1497  C  C   . ALA A 1 194 ? -11.090 23.820  0.842   1.00 33.01  ? 194 ALA A C   1 
ATOM   1498  O  O   . ALA A 1 194 ? -11.840 24.799  0.774   1.00 46.64  ? 194 ALA A O   1 
ATOM   1499  C  CB  . ALA A 1 194 ? -10.626 22.201  -1.002  1.00 31.40  ? 194 ALA A CB  1 
ATOM   1500  N  N   . GLY A 1 195 ? -11.092 23.009  1.886   1.00 31.66  ? 195 GLY A N   1 
ATOM   1501  C  CA  . GLY A 1 195 ? -12.134 23.077  2.887   1.00 38.09  ? 195 GLY A CA  1 
ATOM   1502  C  C   . GLY A 1 195 ? -13.035 21.852  2.839   1.00 36.11  ? 195 GLY A C   1 
ATOM   1503  O  O   . GLY A 1 195 ? -13.005 21.043  1.912   1.00 32.47  ? 195 GLY A O   1 
ATOM   1504  N  N   . THR A 1 196 ? -13.838 21.715  3.876   1.00 38.27  ? 196 THR A N   1 
ATOM   1505  C  CA  . THR A 1 196 ? -14.650 20.516  3.979   1.00 41.39  ? 196 THR A CA  1 
ATOM   1506  C  C   . THR A 1 196 ? -15.914 20.672  3.136   1.00 40.77  ? 196 THR A C   1 
ATOM   1507  O  O   . THR A 1 196 ? -16.449 21.772  2.963   1.00 45.23  ? 196 THR A O   1 
ATOM   1508  C  CB  . THR A 1 196 ? -14.973 20.204  5.445   1.00 39.52  ? 196 THR A CB  1 
ATOM   1509  O  OG1 . THR A 1 196 ? -15.601 18.916  5.537   1.00 40.00  ? 196 THR A OG1 1 
ATOM   1510  C  CG2 . THR A 1 196 ? -15.862 21.290  6.065   1.00 38.58  ? 196 THR A CG2 1 
ATOM   1511  N  N   . ASP A 1 197 ? -16.293 19.588  2.474   1.00 35.63  ? 197 ASP A N   1 
ATOM   1512  C  CA  . ASP A 1 197 ? -17.438 19.668  1.535   1.00 45.36  ? 197 ASP A CA  1 
ATOM   1513  C  C   . ASP A 1 197 ? -18.639 18.871  2.060   1.00 41.68  ? 197 ASP A C   1 
ATOM   1514  O  O   . ASP A 1 197 ? -18.446 17.974  2.886   1.00 39.06  ? 197 ASP A O   1 
ATOM   1515  C  CB  . ASP A 1 197 ? -17.006 19.233  0.131   1.00 39.32  ? 197 ASP A CB  1 
ATOM   1516  C  CG  . ASP A 1 197 ? -18.024 19.516  -0.952  1.00 38.11  ? 197 ASP A CG  1 
ATOM   1517  O  OD1 . ASP A 1 197 ? -18.663 20.579  -0.882  1.00 40.97  ? 197 ASP A OD1 1 
ATOM   1518  O  OD2 . ASP A 1 197 ? -18.158 18.673  -1.854  1.00 33.03  ? 197 ASP A OD2 1 
ATOM   1519  N  N   . THR A 1 198 ? -19.829 19.229  1.600   1.00 35.93  ? 198 THR A N   1 
ATOM   1520  C  CA  . THR A 1 198 ? -21.059 18.526  2.013   1.00 34.39  ? 198 THR A CA  1 
ATOM   1521  C  C   . THR A 1 198 ? -21.744 17.902  0.798   1.00 30.84  ? 198 THR A C   1 
ATOM   1522  O  O   . THR A 1 198 ? -21.453 18.322  -0.320  1.00 28.34  ? 198 THR A O   1 
ATOM   1523  C  CB  . THR A 1 198 ? -22.006 19.499  2.723   1.00 36.10  ? 198 THR A CB  1 
ATOM   1524  O  OG1 . THR A 1 198 ? -22.142 20.631  1.868   1.00 40.92  ? 198 THR A OG1 1 
ATOM   1525  C  CG2 . THR A 1 198 ? -21.501 19.943  4.076   1.00 38.26  ? 198 THR A CG2 1 
ATOM   1526  N  N   . THR A 1 199 ? -22.580 16.895  1.026   1.00 26.18  ? 199 THR A N   1 
ATOM   1527  C  CA  . THR A 1 199 ? -23.394 16.342  -0.044  1.00 22.55  ? 199 THR A CA  1 
ATOM   1528  C  C   . THR A 1 199 ? -24.593 17.246  -0.283  1.00 23.20  ? 199 THR A C   1 
ATOM   1529  O  O   . THR A 1 199 ? -25.198 17.756  0.668   1.00 25.35  ? 199 THR A O   1 
ATOM   1530  C  CB  . THR A 1 199 ? -23.833 14.917  0.308   1.00 24.74  ? 199 THR A CB  1 
ATOM   1531  O  OG1 . THR A 1 199 ? -22.668 14.109  0.462   1.00 23.23  ? 199 THR A OG1 1 
ATOM   1532  C  CG2 . THR A 1 199 ? -24.733 14.310  -0.776  1.00 22.52  ? 199 THR A CG2 1 
ATOM   1533  N  N   . ILE A 1 200 ? -24.875 17.513  -1.571  1.00 25.77  ? 200 ILE A N   1 
ATOM   1534  C  CA  . ILE A 1 200 ? -25.961 18.459  -1.982  1.00 17.72  ? 200 ILE A CA  1 
ATOM   1535  C  C   . ILE A 1 200 ? -27.305 17.757  -1.872  1.00 18.12  ? 200 ILE A C   1 
ATOM   1536  O  O   . ILE A 1 200 ? -27.737 17.139  -2.838  1.00 18.72  ? 200 ILE A O   1 
ATOM   1537  C  CB  . ILE A 1 200 ? -25.678 19.059  -3.370  1.00 22.39  ? 200 ILE A CB  1 
ATOM   1538  C  CG1 . ILE A 1 200 ? -24.228 19.536  -3.479  1.00 22.99  ? 200 ILE A CG1 1 
ATOM   1539  C  CG2 . ILE A 1 200 ? -26.671 20.161  -3.701  1.00 15.78  ? 200 ILE A CG2 1 
ATOM   1540  C  CD1 . ILE A 1 200 ? -23.701 19.591  -4.887  1.00 24.07  ? 200 ILE A CD1 1 
ATOM   1541  N  N   . THR A 1 201 ? -27.956 17.945  -0.739  1.00 20.48  ? 201 THR A N   1 
ATOM   1542  C  CA  . THR A 1 201 ? -29.164 17.196  -0.424  1.00 16.34  ? 201 THR A CA  1 
ATOM   1543  C  C   . THR A 1 201 ? -30.256 17.391  -1.470  1.00 16.61  ? 201 THR A C   1 
ATOM   1544  O  O   . THR A 1 201 ? -30.882 16.415  -1.907  1.00 20.68  ? 201 THR A O   1 
ATOM   1545  C  CB  . THR A 1 201 ? -29.663 17.604  0.966   1.00 13.84  ? 201 THR A CB  1 
ATOM   1546  O  OG1 . THR A 1 201 ? -28.552 17.643  1.859   1.00 18.46  ? 201 THR A OG1 1 
ATOM   1547  C  CG2 . THR A 1 201 ? -30.663 16.588  1.517   1.00 20.99  ? 201 THR A CG2 1 
ATOM   1548  N  N   . VAL A 1 202 ? -30.517 18.634  -1.882  1.00 15.03  ? 202 VAL A N   1 
ATOM   1549  C  CA  . VAL A 1 202 ? -31.605 18.856  -2.838  1.00 14.47  ? 202 VAL A CA  1 
ATOM   1550  C  C   . VAL A 1 202 ? -31.327 18.137  -4.161  1.00 20.32  ? 202 VAL A C   1 
ATOM   1551  O  O   . VAL A 1 202 ? -32.257 17.670  -4.841  1.00 14.96  ? 202 VAL A O   1 
ATOM   1552  C  CB  . VAL A 1 202 ? -31.848 20.366  -3.040  1.00 18.57  ? 202 VAL A CB  1 
ATOM   1553  C  CG1 . VAL A 1 202 ? -30.612 21.061  -3.707  1.00 20.15  ? 202 VAL A CG1 1 
ATOM   1554  C  CG2 . VAL A 1 202 ? -33.136 20.608  -3.833  1.00 17.91  ? 202 VAL A CG2 1 
ATOM   1555  N  N   . ASN A 1 203 ? -30.048 18.021  -4.542  1.00 20.59  ? 203 ASN A N   1 
ATOM   1556  C  CA  . ASN A 1 203 ? -29.705 17.305  -5.764  1.00 21.09  ? 203 ASN A CA  1 
ATOM   1557  C  C   . ASN A 1 203 ? -29.889 15.799  -5.604  1.00 16.81  ? 203 ASN A C   1 
ATOM   1558  O  O   . ASN A 1 203 ? -30.286 15.119  -6.552  1.00 15.91  ? 203 ASN A O   1 
ATOM   1559  C  CB  . ASN A 1 203 ? -28.273 17.633  -6.178  1.00 17.79  ? 203 ASN A CB  1 
ATOM   1560  C  CG  . ASN A 1 203 ? -28.147 19.035  -6.733  1.00 22.37  ? 203 ASN A CG  1 
ATOM   1561  O  OD1 . ASN A 1 203 ? -29.159 19.737  -6.850  1.00 19.34  ? 203 ASN A OD1 1 
ATOM   1562  N  ND2 . ASN A 1 203 ? -26.916 19.458  -7.078  1.00 15.32  ? 203 ASN A ND2 1 
ATOM   1563  N  N   . VAL A 1 204 ? -29.582 15.248  -4.432  1.00 19.77  ? 204 VAL A N   1 
ATOM   1564  C  CA  . VAL A 1 204 ? -29.808 13.811  -4.229  1.00 21.09  ? 204 VAL A CA  1 
ATOM   1565  C  C   . VAL A 1 204 ? -31.287 13.502  -4.382  1.00 21.54  ? 204 VAL A C   1 
ATOM   1566  O  O   . VAL A 1 204 ? -31.684 12.568  -5.094  1.00 22.75  ? 204 VAL A O   1 
ATOM   1567  C  CB  . VAL A 1 204 ? -29.263 13.360  -2.862  1.00 17.95  ? 204 VAL A CB  1 
ATOM   1568  C  CG1 . VAL A 1 204 ? -29.623 11.914  -2.604  1.00 25.19  ? 204 VAL A CG1 1 
ATOM   1569  C  CG2 . VAL A 1 204 ? -27.749 13.515  -2.824  1.00 16.48  ? 204 VAL A CG2 1 
ATOM   1570  N  N   . LEU A 1 205 ? -32.127 14.331  -3.762  1.00 18.85  ? 205 LEU A N   1 
ATOM   1571  C  CA  . LEU A 1 205 ? -33.568 14.156  -3.861  1.00 18.44  ? 205 LEU A CA  1 
ATOM   1572  C  C   . LEU A 1 205 ? -34.052 14.260  -5.304  1.00 18.95  ? 205 LEU A C   1 
ATOM   1573  O  O   . LEU A 1 205 ? -34.901 13.460  -5.729  1.00 16.54  ? 205 LEU A O   1 
ATOM   1574  C  CB  . LEU A 1 205 ? -34.261 15.173  -2.957  1.00 16.14  ? 205 LEU A CB  1 
ATOM   1575  C  CG  . LEU A 1 205 ? -34.110 14.916  -1.450  1.00 16.26  ? 205 LEU A CG  1 
ATOM   1576  C  CD1 . LEU A 1 205 ? -34.432 16.183  -0.653  1.00 14.84  ? 205 LEU A CD1 1 
ATOM   1577  C  CD2 . LEU A 1 205 ? -35.049 13.777  -1.051  1.00 14.27  ? 205 LEU A CD2 1 
ATOM   1578  N  N   . ALA A 1 206 ? -33.544 15.252  -6.067  1.00 16.33  ? 206 ALA A N   1 
ATOM   1579  C  CA  . ALA A 1 206 ? -33.903 15.379  -7.484  1.00 16.40  ? 206 ALA A CA  1 
ATOM   1580  C  C   . ALA A 1 206 ? -33.559 14.112  -8.256  1.00 18.44  ? 206 ALA A C   1 
ATOM   1581  O  O   . ALA A 1 206 ? -34.326 13.658  -9.114  1.00 20.15  ? 206 ALA A O   1 
ATOM   1582  C  CB  . ALA A 1 206 ? -33.200 16.586  -8.121  1.00 17.24  ? 206 ALA A CB  1 
ATOM   1583  N  N   . TRP A 1 207 ? -32.408 13.530  -7.965  1.00 17.69  ? 207 TRP A N   1 
ATOM   1584  C  CA  . TRP A 1 207 ? -31.989 12.329  -8.664  1.00 19.61  ? 207 TRP A CA  1 
ATOM   1585  C  C   . TRP A 1 207 ? -32.835 11.130  -8.245  1.00 20.07  ? 207 TRP A C   1 
ATOM   1586  O  O   . TRP A 1 207 ? -33.132 10.257  -9.068  1.00 18.37  ? 207 TRP A O   1 
ATOM   1587  C  CB  . TRP A 1 207 ? -30.512 12.117  -8.372  1.00 19.51  ? 207 TRP A CB  1 
ATOM   1588  C  CG  . TRP A 1 207 ? -29.926 10.815  -8.745  1.00 22.75  ? 207 TRP A CG  1 
ATOM   1589  C  CD1 . TRP A 1 207 ? -29.532 10.421  -9.984  1.00 23.09  ? 207 TRP A CD1 1 
ATOM   1590  C  CD2 . TRP A 1 207 ? -29.564 9.755   -7.851  1.00 23.41  ? 207 TRP A CD2 1 
ATOM   1591  N  NE1 . TRP A 1 207 ? -28.958 9.181   -9.918  1.00 19.82  ? 207 TRP A NE1 1 
ATOM   1592  C  CE2 . TRP A 1 207 ? -28.955 8.752   -8.622  1.00 21.57  ? 207 TRP A CE2 1 
ATOM   1593  C  CE3 . TRP A 1 207 ? -29.686 9.567   -6.474  1.00 22.38  ? 207 TRP A CE3 1 
ATOM   1594  C  CZ2 . TRP A 1 207 ? -28.499 7.548   -8.070  1.00 24.17  ? 207 TRP A CZ2 1 
ATOM   1595  C  CZ3 . TRP A 1 207 ? -29.211 8.373   -5.923  1.00 22.98  ? 207 TRP A CZ3 1 
ATOM   1596  C  CH2 . TRP A 1 207 ? -28.624 7.388   -6.726  1.00 20.95  ? 207 TRP A CH2 1 
ATOM   1597  N  N   . LEU A 1 208 ? -33.254 11.087  -6.980  1.00 21.73  ? 208 LEU A N   1 
ATOM   1598  C  CA  . LEU A 1 208 ? -34.220 10.076  -6.556  1.00 18.96  ? 208 LEU A CA  1 
ATOM   1599  C  C   . LEU A 1 208 ? -35.524 10.213  -7.334  1.00 22.33  ? 208 LEU A C   1 
ATOM   1600  O  O   . LEU A 1 208 ? -36.125 9.204   -7.736  1.00 16.65  ? 208 LEU A O   1 
ATOM   1601  C  CB  . LEU A 1 208 ? -34.460 10.176  -5.049  1.00 18.15  ? 208 LEU A CB  1 
ATOM   1602  C  CG  . LEU A 1 208 ? -33.254 9.731   -4.221  1.00 20.84  ? 208 LEU A CG  1 
ATOM   1603  C  CD1 . LEU A 1 208 ? -33.473 10.034  -2.744  1.00 20.54  ? 208 LEU A CD1 1 
ATOM   1604  C  CD2 . LEU A 1 208 ? -32.966 8.237   -4.448  1.00 19.12  ? 208 LEU A CD2 1 
ATOM   1605  N  N   . TYR A 1 209 ? -35.947 11.453  -7.608  1.00 17.70  ? 209 TYR A N   1 
ATOM   1606  C  CA  . TYR A 1 209 ? -37.121 11.653  -8.456  1.00 18.23  ? 209 TYR A CA  1 
ATOM   1607  C  C   . TYR A 1 209 ? -36.878 11.161  -9.883  1.00 19.71  ? 209 TYR A C   1 
ATOM   1608  O  O   . TYR A 1 209 ? -37.749 10.525  -10.482 1.00 19.17  ? 209 TYR A O   1 
ATOM   1609  C  CB  . TYR A 1 209 ? -37.537 13.128  -8.457  1.00 18.05  ? 209 TYR A CB  1 
ATOM   1610  C  CG  . TYR A 1 209 ? -38.403 13.484  -7.268  1.00 21.01  ? 209 TYR A CG  1 
ATOM   1611  C  CD1 . TYR A 1 209 ? -39.704 12.974  -7.147  1.00 22.58  ? 209 TYR A CD1 1 
ATOM   1612  C  CD2 . TYR A 1 209 ? -37.924 14.305  -6.259  1.00 19.16  ? 209 TYR A CD2 1 
ATOM   1613  C  CE1 . TYR A 1 209 ? -40.508 13.279  -6.049  1.00 24.56  ? 209 TYR A CE1 1 
ATOM   1614  C  CE2 . TYR A 1 209 ? -38.724 14.623  -5.149  1.00 27.94  ? 209 TYR A CE2 1 
ATOM   1615  C  CZ  . TYR A 1 209 ? -40.021 14.106  -5.049  1.00 27.16  ? 209 TYR A CZ  1 
ATOM   1616  O  OH  . TYR A 1 209 ? -40.808 14.422  -3.950  1.00 23.65  ? 209 TYR A OH  1 
ATOM   1617  N  N   . ALA A 1 210 ? -35.717 11.476  -10.463 1.00 23.95  ? 210 ALA A N   1 
ATOM   1618  C  CA  . ALA A 1 210 ? -35.392 10.931  -11.778 1.00 22.47  ? 210 ALA A CA  1 
ATOM   1619  C  C   . ALA A 1 210 ? -35.471 9.409   -11.778 1.00 20.13  ? 210 ALA A C   1 
ATOM   1620  O  O   . ALA A 1 210 ? -35.962 8.807   -12.733 1.00 19.18  ? 210 ALA A O   1 
ATOM   1621  C  CB  . ALA A 1 210 ? -34.008 11.401  -12.220 1.00 21.78  ? 210 ALA A CB  1 
ATOM   1622  N  N   . ALA A 1 211 ? -35.010 8.766   -10.708 1.00 24.50  ? 211 ALA A N   1 
ATOM   1623  C  CA  . ALA A 1 211 ? -35.050 7.303   -10.667 1.00 24.21  ? 211 ALA A CA  1 
ATOM   1624  C  C   . ALA A 1 211 ? -36.483 6.789   -10.776 1.00 21.36  ? 211 ALA A C   1 
ATOM   1625  O  O   . ALA A 1 211 ? -36.785 5.908   -11.589 1.00 22.56  ? 211 ALA A O   1 
ATOM   1626  C  CB  . ALA A 1 211 ? -34.393 6.812   -9.383  1.00 18.24  ? 211 ALA A CB  1 
ATOM   1627  N  N   . VAL A 1 212 ? -37.392 7.375   -10.001 1.00 24.11  ? 212 VAL A N   1 
ATOM   1628  C  CA  . VAL A 1 212 ? -38.794 6.963   -10.044 1.00 27.79  ? 212 VAL A CA  1 
ATOM   1629  C  C   . VAL A 1 212 ? -39.375 7.181   -11.435 1.00 29.97  ? 212 VAL A C   1 
ATOM   1630  O  O   . VAL A 1 212 ? -40.026 6.285   -11.999 1.00 26.35  ? 212 VAL A O   1 
ATOM   1631  C  CB  . VAL A 1 212 ? -39.598 7.703   -8.962  1.00 26.07  ? 212 VAL A CB  1 
ATOM   1632  C  CG1 . VAL A 1 212 ? -41.067 7.449   -9.149  1.00 27.36  ? 212 VAL A CG1 1 
ATOM   1633  C  CG2 . VAL A 1 212 ? -39.170 7.204   -7.598  1.00 21.99  ? 212 VAL A CG2 1 
ATOM   1634  N  N   . ILE A 1 213 ? -39.128 8.367   -12.017 1.00 24.94  ? 213 ILE A N   1 
ATOM   1635  C  CA  . ILE A 1 213 ? -39.571 8.661   -13.381 1.00 21.09  ? 213 ILE A CA  1 
ATOM   1636  C  C   . ILE A 1 213 ? -39.084 7.596   -14.347 1.00 27.20  ? 213 ILE A C   1 
ATOM   1637  O  O   . ILE A 1 213 ? -39.786 7.242   -15.308 1.00 29.67  ? 213 ILE A O   1 
ATOM   1638  C  CB  . ILE A 1 213 ? -39.091 10.069  -13.813 1.00 27.93  ? 213 ILE A CB  1 
ATOM   1639  C  CG1 . ILE A 1 213 ? -39.845 11.185  -13.079 1.00 27.56  ? 213 ILE A CG1 1 
ATOM   1640  C  CG2 . ILE A 1 213 ? -39.188 10.264  -15.316 1.00 28.73  ? 213 ILE A CG2 1 
ATOM   1641  C  CD1 . ILE A 1 213 ? -39.157 12.529  -13.214 1.00 24.21  ? 213 ILE A CD1 1 
ATOM   1642  N  N   . ASN A 1 214 ? -37.893 7.044   -14.100 1.00 23.67  ? 214 ASN A N   1 
ATOM   1643  C  CA  . ASN A 1 214 ? -37.292 6.052   -14.979 1.00 24.46  ? 214 ASN A CA  1 
ATOM   1644  C  C   . ASN A 1 214 ? -37.502 4.609   -14.495 1.00 26.53  ? 214 ASN A C   1 
ATOM   1645  O  O   . ASN A 1 214 ? -36.750 3.718   -14.899 1.00 25.85  ? 214 ASN A O   1 
ATOM   1646  C  CB  . ASN A 1 214 ? -35.810 6.369   -15.169 1.00 23.19  ? 214 ASN A CB  1 
ATOM   1647  C  CG  . ASN A 1 214 ? -35.598 7.559   -16.109 1.00 30.86  ? 214 ASN A CG  1 
ATOM   1648  O  OD1 . ASN A 1 214 ? -35.534 7.404   -17.344 1.00 31.79  ? 214 ASN A OD1 1 
ATOM   1649  N  ND2 . ASN A 1 214 ? -35.540 8.765   -15.530 1.00 25.60  ? 214 ASN A ND2 1 
ATOM   1650  N  N   . GLY A 1 215 ? -38.463 4.372   -13.594 1.00 28.90  ? 215 GLY A N   1 
ATOM   1651  C  CA  . GLY A 1 215 ? -38.839 3.022   -13.201 1.00 25.88  ? 215 GLY A CA  1 
ATOM   1652  C  C   . GLY A 1 215 ? -38.115 2.423   -12.002 1.00 28.75  ? 215 GLY A C   1 
ATOM   1653  O  O   . GLY A 1 215 ? -38.409 1.280   -11.637 1.00 33.82  ? 215 GLY A O   1 
ATOM   1654  N  N   . ASP A 1 216 ? -37.150 3.125   -11.412 1.00 28.41  ? 216 ASP A N   1 
ATOM   1655  C  CA  . ASP A 1 216 ? -36.467 2.678   -10.200 1.00 26.72  ? 216 ASP A CA  1 
ATOM   1656  C  C   . ASP A 1 216 ? -37.251 3.142   -8.973  1.00 29.21  ? 216 ASP A C   1 
ATOM   1657  O  O   . ASP A 1 216 ? -37.344 4.347   -8.708  1.00 29.47  ? 216 ASP A O   1 
ATOM   1658  C  CB  . ASP A 1 216 ? -35.031 3.192   -10.169 1.00 35.18  ? 216 ASP A CB  1 
ATOM   1659  C  CG  . ASP A 1 216 ? -34.068 2.259   -10.893 1.00 33.38  ? 216 ASP A CG  1 
ATOM   1660  O  OD1 . ASP A 1 216 ? -34.513 1.168   -11.296 1.00 37.40  ? 216 ASP A OD1 1 
ATOM   1661  O  OD2 . ASP A 1 216 ? -32.884 2.612   -11.068 1.00 29.76  ? 216 ASP A OD2 1 
ATOM   1662  N  N   . ARG A 1 217 ? -37.836 2.184   -8.235  1.00 25.80  ? 217 ARG A N   1 
ATOM   1663  C  CA  . ARG A 1 217 ? -38.760 2.495   -7.153  1.00 25.14  ? 217 ARG A CA  1 
ATOM   1664  C  C   . ARG A 1 217 ? -38.486 1.762   -5.847  1.00 27.65  ? 217 ARG A C   1 
ATOM   1665  O  O   . ARG A 1 217 ? -39.119 2.105   -4.841  1.00 30.47  ? 217 ARG A O   1 
ATOM   1666  C  CB  . ARG A 1 217 ? -40.208 2.162   -7.548  1.00 29.84  ? 217 ARG A CB  1 
ATOM   1667  C  CG  . ARG A 1 217 ? -40.708 2.826   -8.793  1.00 33.23  ? 217 ARG A CG  1 
ATOM   1668  C  CD  . ARG A 1 217 ? -42.170 2.473   -9.033  1.00 34.86  ? 217 ARG A CD  1 
ATOM   1669  N  NE  . ARG A 1 217 ? -42.717 3.251   -10.141 1.00 36.15  ? 217 ARG A NE  1 
ATOM   1670  C  CZ  . ARG A 1 217 ? -43.185 4.478   -10.009 1.00 37.25  ? 217 ARG A CZ  1 
ATOM   1671  N  NH1 . ARG A 1 217 ? -43.203 5.065   -8.840  1.00 35.98  ? 217 ARG A NH1 1 
ATOM   1672  N  NH2 . ARG A 1 217 ? -43.657 5.121   -11.075 1.00 38.25  ? 217 ARG A NH2 1 
ATOM   1673  N  N   . TRP A 1 218 ? -37.546 0.815   -5.802  1.00 23.31  ? 218 TRP A N   1 
ATOM   1674  C  CA  . TRP A 1 218 ? -37.421 -0.036  -4.616  1.00 26.48  ? 218 TRP A CA  1 
ATOM   1675  C  C   . TRP A 1 218 ? -37.150 0.750   -3.341  1.00 30.91  ? 218 TRP A C   1 
ATOM   1676  O  O   . TRP A 1 218 ? -37.395 0.228   -2.250  1.00 27.07  ? 218 TRP A O   1 
ATOM   1677  C  CB  . TRP A 1 218 ? -36.326 -1.084  -4.814  1.00 23.04  ? 218 TRP A CB  1 
ATOM   1678  C  CG  . TRP A 1 218 ? -34.973 -0.534  -5.163  1.00 25.81  ? 218 TRP A CG  1 
ATOM   1679  C  CD1 . TRP A 1 218 ? -34.448 -0.398  -6.425  1.00 29.79  ? 218 TRP A CD1 1 
ATOM   1680  C  CD2 . TRP A 1 218 ? -33.976 -0.024  -4.261  1.00 29.99  ? 218 TRP A CD2 1 
ATOM   1681  N  NE1 . TRP A 1 218 ? -33.191 0.145   -6.358  1.00 25.89  ? 218 TRP A NE1 1 
ATOM   1682  C  CE2 . TRP A 1 218 ? -32.879 0.389   -5.042  1.00 31.20  ? 218 TRP A CE2 1 
ATOM   1683  C  CE3 . TRP A 1 218 ? -33.901 0.119   -2.870  1.00 28.62  ? 218 TRP A CE3 1 
ATOM   1684  C  CZ2 . TRP A 1 218 ? -31.718 0.922   -4.470  1.00 29.43  ? 218 TRP A CZ2 1 
ATOM   1685  C  CZ3 . TRP A 1 218 ? -32.754 0.642   -2.315  1.00 30.64  ? 218 TRP A CZ3 1 
ATOM   1686  C  CH2 . TRP A 1 218 ? -31.681 1.043   -3.112  1.00 28.30  ? 218 TRP A CH2 1 
ATOM   1687  N  N   . PHE A 1 219 ? -36.633 1.977   -3.449  1.00 24.45  ? 219 PHE A N   1 
ATOM   1688  C  CA  . PHE A 1 219 ? -36.253 2.749   -2.278  1.00 21.05  ? 219 PHE A CA  1 
ATOM   1689  C  C   . PHE A 1 219 ? -37.433 3.509   -1.680  1.00 23.68  ? 219 PHE A C   1 
ATOM   1690  O  O   . PHE A 1 219 ? -37.285 4.126   -0.621  1.00 25.82  ? 219 PHE A O   1 
ATOM   1691  C  CB  . PHE A 1 219 ? -35.128 3.717   -2.652  1.00 22.49  ? 219 PHE A CB  1 
ATOM   1692  C  CG  . PHE A 1 219 ? -35.466 4.594   -3.846  1.00 25.75  ? 219 PHE A CG  1 
ATOM   1693  C  CD1 . PHE A 1 219 ? -36.157 5.797   -3.678  1.00 23.23  ? 219 PHE A CD1 1 
ATOM   1694  C  CD2 . PHE A 1 219 ? -35.136 4.193   -5.136  1.00 24.24  ? 219 PHE A CD2 1 
ATOM   1695  C  CE1 . PHE A 1 219 ? -36.488 6.599   -4.787  1.00 22.61  ? 219 PHE A CE1 1 
ATOM   1696  C  CE2 . PHE A 1 219 ? -35.469 4.982   -6.237  1.00 24.60  ? 219 PHE A CE2 1 
ATOM   1697  C  CZ  . PHE A 1 219 ? -36.144 6.189   -6.059  1.00 19.65  ? 219 PHE A CZ  1 
ATOM   1698  N  N   . LEU A 1 220 ? -38.594 3.498   -2.331  1.00 25.74  ? 220 LEU A N   1 
ATOM   1699  C  CA  . LEU A 1 220 ? -39.764 4.143   -1.744  1.00 29.06  ? 220 LEU A CA  1 
ATOM   1700  C  C   . LEU A 1 220 ? -40.279 3.275   -0.603  1.00 31.22  ? 220 LEU A C   1 
ATOM   1701  O  O   . LEU A 1 220 ? -40.460 2.064   -0.763  1.00 30.66  ? 220 LEU A O   1 
ATOM   1702  C  CB  . LEU A 1 220 ? -40.850 4.341   -2.807  1.00 25.26  ? 220 LEU A CB  1 
ATOM   1703  C  CG  . LEU A 1 220 ? -40.474 5.224   -4.006  1.00 26.26  ? 220 LEU A CG  1 
ATOM   1704  C  CD1 . LEU A 1 220 ? -41.512 5.155   -5.123  1.00 26.56  ? 220 LEU A CD1 1 
ATOM   1705  C  CD2 . LEU A 1 220 ? -40.286 6.670   -3.557  1.00 25.25  ? 220 LEU A CD2 1 
ATOM   1706  N  N   . ASN A 1 221 ? -40.569 3.897   0.533   1.00 32.62  ? 221 ASN A N   1 
ATOM   1707  C  CA  . ASN A 1 221 ? -40.982 3.127   1.700   1.00 31.59  ? 221 ASN A CA  1 
ATOM   1708  C  C   . ASN A 1 221 ? -42.303 3.620   2.278   1.00 35.67  ? 221 ASN A C   1 
ATOM   1709  O  O   . ASN A 1 221 ? -42.995 4.438   1.660   1.00 36.08  ? 221 ASN A O   1 
ATOM   1710  C  CB  . ASN A 1 221 ? -39.876 3.122   2.761   1.00 32.44  ? 221 ASN A CB  1 
ATOM   1711  C  CG  . ASN A 1 221 ? -39.496 4.517   3.238   1.00 34.09  ? 221 ASN A CG  1 
ATOM   1712  O  OD1 . ASN A 1 221 ? -40.312 5.434   3.237   1.00 29.99  ? 221 ASN A OD1 1 
ATOM   1713  N  ND2 . ASN A 1 221 ? -38.248 4.669   3.682   1.00 32.02  ? 221 ASN A ND2 1 
ATOM   1714  N  N   . ARG A 1 222 ? -42.665 3.111   3.453   1.00 40.39  ? 222 ARG A N   1 
ATOM   1715  C  CA  . ARG A 1 222 ? -43.945 3.413   4.079   1.00 46.25  ? 222 ARG A CA  1 
ATOM   1716  C  C   . ARG A 1 222 ? -43.885 4.620   5.009   1.00 43.40  ? 222 ARG A C   1 
ATOM   1717  O  O   . ARG A 1 222 ? -44.853 4.885   5.729   1.00 47.88  ? 222 ARG A O   1 
ATOM   1718  C  CB  . ARG A 1 222 ? -44.401 2.201   4.895   1.00 46.50  ? 222 ARG A CB  1 
ATOM   1719  C  CG  . ARG A 1 222 ? -44.763 0.974   4.088   1.00 56.18  ? 222 ARG A CG  1 
ATOM   1720  C  CD  . ARG A 1 222 ? -45.241 -0.152  4.996   1.00 67.94  ? 222 ARG A CD  1 
ATOM   1721  N  NE  . ARG A 1 222 ? -45.746 -1.282  4.228   1.00 78.12  ? 222 ARG A NE  1 
ATOM   1722  C  CZ  . ARG A 1 222 ? -47.008 -1.421  3.848   1.00 87.36  ? 222 ARG A CZ  1 
ATOM   1723  N  NH1 . ARG A 1 222 ? -47.923 -0.511  4.140   1.00 93.54  ? 222 ARG A NH1 1 
ATOM   1724  N  NH2 . ARG A 1 222 ? -47.357 -2.492  3.140   1.00 80.53  ? 222 ARG A NH2 1 
ATOM   1725  N  N   . PHE A 1 223 ? -42.788 5.358   5.005   1.00 36.70  ? 223 PHE A N   1 
ATOM   1726  C  CA  . PHE A 1 223 ? -42.559 6.384   6.004   1.00 36.58  ? 223 PHE A CA  1 
ATOM   1727  C  C   . PHE A 1 223 ? -42.729 7.782   5.429   1.00 32.54  ? 223 PHE A C   1 
ATOM   1728  O  O   . PHE A 1 223 ? -42.639 8.012   4.218   1.00 31.21  ? 223 PHE A O   1 
ATOM   1729  C  CB  . PHE A 1 223 ? -41.150 6.232   6.583   1.00 35.49  ? 223 PHE A CB  1 
ATOM   1730  C  CG  . PHE A 1 223 ? -40.846 4.836   7.068   1.00 41.91  ? 223 PHE A CG  1 
ATOM   1731  C  CD1 . PHE A 1 223 ? -41.863 3.993   7.502   1.00 43.21  ? 223 PHE A CD1 1 
ATOM   1732  C  CD2 . PHE A 1 223 ? -39.546 4.346   7.032   1.00 39.55  ? 223 PHE A CD2 1 
ATOM   1733  C  CE1 . PHE A 1 223 ? -41.590 2.701   7.914   1.00 44.78  ? 223 PHE A CE1 1 
ATOM   1734  C  CE2 . PHE A 1 223 ? -39.267 3.060   7.442   1.00 44.94  ? 223 PHE A CE2 1 
ATOM   1735  C  CZ  . PHE A 1 223 ? -40.293 2.234   7.885   1.00 42.62  ? 223 PHE A CZ  1 
ATOM   1736  N  N   . THR A 1 224 ? -42.916 8.728   6.336   1.00 34.00  ? 224 THR A N   1 
ATOM   1737  C  CA  . THR A 1 224 ? -42.776 10.142  6.049   1.00 29.74  ? 224 THR A CA  1 
ATOM   1738  C  C   . THR A 1 224 ? -41.877 10.699  7.140   1.00 31.56  ? 224 THR A C   1 
ATOM   1739  O  O   . THR A 1 224 ? -41.533 9.999   8.095   1.00 31.12  ? 224 THR A O   1 
ATOM   1740  C  CB  . THR A 1 224 ? -44.139 10.859  5.996   1.00 30.62  ? 224 THR A CB  1 
ATOM   1741  O  OG1 . THR A 1 224 ? -44.016 12.098  5.283   1.00 30.66  ? 224 THR A OG1 1 
ATOM   1742  C  CG2 . THR A 1 224 ? -44.653 11.149  7.391   1.00 29.70  ? 224 THR A CG2 1 
ATOM   1743  N  N   . THR A 1 225 ? -41.484 11.960  7.001   1.00 33.96  ? 225 THR A N   1 
ATOM   1744  C  CA  . THR A 1 225 ? -40.624 12.600  7.985   1.00 32.24  ? 225 THR A CA  1 
ATOM   1745  C  C   . THR A 1 225 ? -40.984 14.078  8.019   1.00 30.67  ? 225 THR A C   1 
ATOM   1746  O  O   . THR A 1 225 ? -41.883 14.530  7.310   1.00 32.40  ? 225 THR A O   1 
ATOM   1747  C  CB  . THR A 1 225 ? -39.140 12.397  7.640   1.00 36.56  ? 225 THR A CB  1 
ATOM   1748  O  OG1 . THR A 1 225 ? -38.315 12.743  8.763   1.00 34.16  ? 225 THR A OG1 1 
ATOM   1749  C  CG2 . THR A 1 225 ? -38.753 13.287  6.448   1.00 35.54  ? 225 THR A CG2 1 
ATOM   1750  N  N   . THR A 1 226 ? -40.314 14.824  8.886   1.00 32.68  ? 226 THR A N   1 
ATOM   1751  C  CA  . THR A 1 226 ? -40.389 16.271  8.845   1.00 33.28  ? 226 THR A CA  1 
ATOM   1752  C  C   . THR A 1 226 ? -39.018 16.819  8.480   1.00 31.54  ? 226 THR A C   1 
ATOM   1753  O  O   . THR A 1 226 ? -38.001 16.125  8.600   1.00 26.98  ? 226 THR A O   1 
ATOM   1754  C  CB  . THR A 1 226 ? -40.868 16.873  10.176  1.00 30.10  ? 226 THR A CB  1 
ATOM   1755  O  OG1 . THR A 1 226 ? -39.856 16.724  11.189  1.00 27.31  ? 226 THR A OG1 1 
ATOM   1756  C  CG2 . THR A 1 226 ? -42.175 16.212  10.590  1.00 30.90  ? 226 THR A CG2 1 
ATOM   1757  N  N   . LEU A 1 227 ? -39.005 18.089  8.054   1.00 27.16  ? 227 LEU A N   1 
ATOM   1758  C  CA  . LEU A 1 227 ? -37.742 18.748  7.756   1.00 27.06  ? 227 LEU A CA  1 
ATOM   1759  C  C   . LEU A 1 227 ? -36.802 18.690  8.945   1.00 28.27  ? 227 LEU A C   1 
ATOM   1760  O  O   . LEU A 1 227 ? -35.629 18.331  8.798   1.00 29.45  ? 227 LEU A O   1 
ATOM   1761  C  CB  . LEU A 1 227 ? -38.003 20.202  7.356   1.00 29.36  ? 227 LEU A CB  1 
ATOM   1762  C  CG  . LEU A 1 227 ? -37.244 20.754  6.151   1.00 28.40  ? 227 LEU A CG  1 
ATOM   1763  C  CD1 . LEU A 1 227 ? -37.231 19.750  5.031   1.00 26.41  ? 227 LEU A CD1 1 
ATOM   1764  C  CD2 . LEU A 1 227 ? -37.861 22.054  5.695   1.00 22.88  ? 227 LEU A CD2 1 
ATOM   1765  N  N   . ASN A 1 228 ? -37.326 18.932  10.146  1.00 27.88  ? 228 ASN A N   1 
ATOM   1766  C  CA  . ASN A 1 228 ? -36.480 18.960  11.334  1.00 30.99  ? 228 ASN A CA  1 
ATOM   1767  C  C   . ASN A 1 228 ? -35.877 17.590  11.612  1.00 30.66  ? 228 ASN A C   1 
ATOM   1768  O  O   . ASN A 1 228 ? -34.670 17.466  11.840  1.00 32.54  ? 228 ASN A O   1 
ATOM   1769  C  CB  . ASN A 1 228 ? -37.282 19.442  12.546  1.00 38.17  ? 228 ASN A CB  1 
ATOM   1770  C  CG  . ASN A 1 228 ? -37.499 20.947  12.558  1.00 51.19  ? 228 ASN A CG  1 
ATOM   1771  O  OD1 . ASN A 1 228 ? -37.760 21.531  13.619  1.00 54.28  ? 228 ASN A OD1 1 
ATOM   1772  N  ND2 . ASN A 1 228 ? -37.392 21.587  11.388  1.00 41.76  ? 228 ASN A ND2 1 
ATOM   1773  N  N   . ASP A 1 229 ? -36.702 16.545  11.625  1.00 34.93  ? 229 ASP A N   1 
ATOM   1774  C  CA  . ASP A 1 229 ? -36.142 15.230  11.914  1.00 36.46  ? 229 ASP A CA  1 
ATOM   1775  C  C   . ASP A 1 229 ? -35.203 14.781  10.805  1.00 32.78  ? 229 ASP A C   1 
ATOM   1776  O  O   . ASP A 1 229 ? -34.196 14.121  11.081  1.00 34.93  ? 229 ASP A O   1 
ATOM   1777  C  CB  . ASP A 1 229 ? -37.245 14.196  12.140  1.00 39.72  ? 229 ASP A CB  1 
ATOM   1778  C  CG  . ASP A 1 229 ? -37.642 14.086  13.601  1.00 53.05  ? 229 ASP A CG  1 
ATOM   1779  O  OD1 . ASP A 1 229 ? -37.356 15.034  14.370  1.00 54.16  ? 229 ASP A OD1 1 
ATOM   1780  O  OD2 . ASP A 1 229 ? -38.196 13.033  13.995  1.00 62.75  ? 229 ASP A OD2 1 
ATOM   1781  N  N   . PHE A 1 230 ? -35.508 15.138  9.548   1.00 29.48  ? 230 PHE A N   1 
ATOM   1782  C  CA  . PHE A 1 230 ? -34.613 14.797  8.440   1.00 27.91  ? 230 PHE A CA  1 
ATOM   1783  C  C   . PHE A 1 230 ? -33.270 15.494  8.589   1.00 27.21  ? 230 PHE A C   1 
ATOM   1784  O  O   . PHE A 1 230 ? -32.212 14.881  8.397   1.00 31.98  ? 230 PHE A O   1 
ATOM   1785  C  CB  . PHE A 1 230 ? -35.233 15.165  7.091   1.00 29.73  ? 230 PHE A CB  1 
ATOM   1786  C  CG  . PHE A 1 230 ? -34.327 14.882  5.920   1.00 26.00  ? 230 PHE A CG  1 
ATOM   1787  C  CD1 . PHE A 1 230 ? -34.255 13.612  5.380   1.00 25.59  ? 230 PHE A CD1 1 
ATOM   1788  C  CD2 . PHE A 1 230 ? -33.507 15.872  5.398   1.00 30.42  ? 230 PHE A CD2 1 
ATOM   1789  C  CE1 . PHE A 1 230 ? -33.418 13.336  4.323   1.00 25.37  ? 230 PHE A CE1 1 
ATOM   1790  C  CE2 . PHE A 1 230 ? -32.647 15.603  4.345   1.00 26.47  ? 230 PHE A CE2 1 
ATOM   1791  C  CZ  . PHE A 1 230 ? -32.605 14.341  3.802   1.00 31.64  ? 230 PHE A CZ  1 
ATOM   1792  N  N   . ASN A 1 231 ? -33.291 16.789  8.909   1.00 30.33  ? 231 ASN A N   1 
ATOM   1793  C  CA  . ASN A 1 231 ? -32.037 17.517  9.037   1.00 30.84  ? 231 ASN A CA  1 
ATOM   1794  C  C   . ASN A 1 231 ? -31.210 17.017  10.215  1.00 28.62  ? 231 ASN A C   1 
ATOM   1795  O  O   . ASN A 1 231 ? -29.983 17.140  10.191  1.00 32.35  ? 231 ASN A O   1 
ATOM   1796  C  CB  . ASN A 1 231 ? -32.319 19.018  9.105   1.00 30.29  ? 231 ASN A CB  1 
ATOM   1797  C  CG  . ASN A 1 231 ? -32.538 19.624  7.717   1.00 29.52  ? 231 ASN A CG  1 
ATOM   1798  O  OD1 . ASN A 1 231 ? -31.878 19.237  6.753   1.00 34.29  ? 231 ASN A OD1 1 
ATOM   1799  N  ND2 . ASN A 1 231 ? -33.489 20.534  7.604   1.00 29.70  ? 231 ASN A ND2 1 
ATOM   1800  N  N   . LEU A 1 232 ? -31.846 16.453  11.248  1.00 27.53  ? 232 LEU A N   1 
ATOM   1801  C  CA  . LEU A 1 232 ? -31.083 15.745  12.275  1.00 29.10  ? 232 LEU A CA  1 
ATOM   1802  C  C   . LEU A 1 232 ? -30.238 14.637  11.662  1.00 30.28  ? 232 LEU A C   1 
ATOM   1803  O  O   . LEU A 1 232 ? -29.085 14.426  12.056  1.00 34.57  ? 232 LEU A O   1 
ATOM   1804  C  CB  . LEU A 1 232 ? -32.003 15.151  13.341  1.00 29.25  ? 232 LEU A CB  1 
ATOM   1805  C  CG  . LEU A 1 232 ? -32.199 15.953  14.638  1.00 49.11  ? 232 LEU A CG  1 
ATOM   1806  C  CD1 . LEU A 1 232 ? -32.691 15.039  15.780  1.00 42.65  ? 232 LEU A CD1 1 
ATOM   1807  C  CD2 . LEU A 1 232 ? -30.955 16.757  15.049  1.00 36.93  ? 232 LEU A CD2 1 
ATOM   1808  N  N   . VAL A 1 233 ? -30.807 13.901  10.711  1.00 32.82  ? 233 VAL A N   1 
ATOM   1809  C  CA  . VAL A 1 233 ? -30.108 12.765  10.118  1.00 35.77  ? 233 VAL A CA  1 
ATOM   1810  C  C   . VAL A 1 233 ? -29.058 13.233  9.128   1.00 34.67  ? 233 VAL A C   1 
ATOM   1811  O  O   . VAL A 1 233 ? -27.916 12.764  9.148   1.00 30.28  ? 233 VAL A O   1 
ATOM   1812  C  CB  . VAL A 1 233 ? -31.119 11.814  9.459   1.00 33.57  ? 233 VAL A CB  1 
ATOM   1813  C  CG1 . VAL A 1 233 ? -30.418 10.545  8.995   1.00 30.55  ? 233 VAL A CG1 1 
ATOM   1814  C  CG2 . VAL A 1 233 ? -32.249 11.513  10.437  1.00 29.21  ? 233 VAL A CG2 1 
ATOM   1815  N  N   . ALA A 1 234 ? -29.430 14.175  8.259   1.00 33.87  ? 234 ALA A N   1 
ATOM   1816  C  CA  . ALA A 1 234 ? -28.517 14.665  7.229   1.00 32.39  ? 234 ALA A CA  1 
ATOM   1817  C  C   . ALA A 1 234 ? -27.238 15.256  7.826   1.00 34.50  ? 234 ALA A C   1 
ATOM   1818  O  O   . ALA A 1 234 ? -26.148 15.103  7.255   1.00 34.63  ? 234 ALA A O   1 
ATOM   1819  C  CB  . ALA A 1 234 ? -29.241 15.699  6.371   1.00 37.73  ? 234 ALA A CB  1 
ATOM   1820  N  N   . MET A 1 235 ? -27.355 15.961  8.955   1.00 34.59  ? 235 MET A N   1 
ATOM   1821  C  CA  . MET A 1 235 ? -26.183 16.563  9.587   1.00 33.20  ? 235 MET A CA  1 
ATOM   1822  C  C   . MET A 1 235 ? -25.163 15.508  10.013  1.00 36.53  ? 235 MET A C   1 
ATOM   1823  O  O   . MET A 1 235 ? -23.952 15.717  9.865   1.00 34.24  ? 235 MET A O   1 
ATOM   1824  C  CB  . MET A 1 235 ? -26.631 17.397  10.788  1.00 37.00  ? 235 MET A CB  1 
ATOM   1825  C  CG  . MET A 1 235 ? -25.525 18.149  11.518  1.00 54.33  ? 235 MET A CG  1 
ATOM   1826  S  SD  . MET A 1 235 ? -26.151 19.423  12.663  1.00 73.94  ? 235 MET A SD  1 
ATOM   1827  C  CE  . MET A 1 235 ? -25.401 18.940  14.219  1.00 53.68  ? 235 MET A CE  1 
ATOM   1828  N  N   . LYS A 1 236 ? -25.632 14.369  10.548  1.00 32.61  ? 236 LYS A N   1 
ATOM   1829  C  CA  . LYS A 1 236 ? -24.724 13.291  10.936  1.00 33.24  ? 236 LYS A CA  1 
ATOM   1830  C  C   . LYS A 1 236 ? -23.937 12.771  9.744   1.00 34.24  ? 236 LYS A C   1 
ATOM   1831  O  O   . LYS A 1 236 ? -22.756 12.432  9.870   1.00 39.04  ? 236 LYS A O   1 
ATOM   1832  C  CB  . LYS A 1 236 ? -25.495 12.125  11.572  1.00 39.01  ? 236 LYS A CB  1 
ATOM   1833  C  CG  . LYS A 1 236 ? -26.138 12.398  12.923  1.00 47.31  ? 236 LYS A CG  1 
ATOM   1834  C  CD  . LYS A 1 236 ? -27.167 11.308  13.273  1.00 52.49  ? 236 LYS A CD  1 
ATOM   1835  C  CE  . LYS A 1 236 ? -28.021 11.706  14.482  1.00 52.96  ? 236 LYS A CE  1 
ATOM   1836  N  NZ  . LYS A 1 236 ? -29.305 10.949  14.576  1.00 55.15  ? 236 LYS A NZ  1 
ATOM   1837  N  N   . TYR A 1 237 ? -24.561 12.739  8.568   1.00 33.38  ? 237 TYR A N   1 
ATOM   1838  C  CA  . TYR A 1 237 ? -23.945 12.187  7.372   1.00 34.68  ? 237 TYR A CA  1 
ATOM   1839  C  C   . TYR A 1 237 ? -23.327 13.260  6.482   1.00 31.29  ? 237 TYR A C   1 
ATOM   1840  O  O   . TYR A 1 237 ? -23.025 12.982  5.317   1.00 31.31  ? 237 TYR A O   1 
ATOM   1841  C  CB  . TYR A 1 237 ? -24.967 11.385  6.572   1.00 27.00  ? 237 TYR A CB  1 
ATOM   1842  C  CG  . TYR A 1 237 ? -25.418 10.125  7.262   1.00 33.99  ? 237 TYR A CG  1 
ATOM   1843  C  CD1 . TYR A 1 237 ? -26.440 10.152  8.203   1.00 30.16  ? 237 TYR A CD1 1 
ATOM   1844  C  CD2 . TYR A 1 237 ? -24.830 8.902   6.972   1.00 32.80  ? 237 TYR A CD2 1 
ATOM   1845  C  CE1 . TYR A 1 237 ? -26.860 8.992   8.835   1.00 35.46  ? 237 TYR A CE1 1 
ATOM   1846  C  CE2 . TYR A 1 237 ? -25.243 7.749   7.598   1.00 30.19  ? 237 TYR A CE2 1 
ATOM   1847  C  CZ  . TYR A 1 237 ? -26.252 7.799   8.527   1.00 28.64  ? 237 TYR A CZ  1 
ATOM   1848  O  OH  . TYR A 1 237 ? -26.661 6.652   9.147   1.00 34.48  ? 237 TYR A OH  1 
ATOM   1849  N  N   . ASN A 1 238 ? -23.125 14.468  7.001   1.00 25.07  ? 238 ASN A N   1 
ATOM   1850  C  CA  . ASN A 1 238 ? -22.451 15.525  6.247   1.00 34.25  ? 238 ASN A CA  1 
ATOM   1851  C  C   . ASN A 1 238 ? -23.230 15.894  4.977   1.00 30.81  ? 238 ASN A C   1 
ATOM   1852  O  O   . ASN A 1 238 ? -22.654 16.133  3.913   1.00 30.84  ? 238 ASN A O   1 
ATOM   1853  C  CB  . ASN A 1 238 ? -21.008 15.131  5.914   1.00 38.08  ? 238 ASN A CB  1 
ATOM   1854  C  CG  . ASN A 1 238 ? -20.139 16.325  5.580   1.00 41.37  ? 238 ASN A CG  1 
ATOM   1855  O  OD1 . ASN A 1 238 ? -20.383 17.440  6.043   1.00 42.53  ? 238 ASN A OD1 1 
ATOM   1856  N  ND2 . ASN A 1 238 ? -19.134 16.104  4.737   1.00 44.15  ? 238 ASN A ND2 1 
ATOM   1857  N  N   . TYR A 1 239 ? -24.552 15.907  5.087   1.00 32.94  ? 239 TYR A N   1 
ATOM   1858  C  CA  . TYR A 1 239 ? -25.449 16.434  4.074   1.00 23.23  ? 239 TYR A CA  1 
ATOM   1859  C  C   . TYR A 1 239 ? -25.836 17.875  4.402   1.00 25.39  ? 239 TYR A C   1 
ATOM   1860  O  O   . TYR A 1 239 ? -26.000 18.247  5.566   1.00 23.23  ? 239 TYR A O   1 
ATOM   1861  C  CB  . TYR A 1 239 ? -26.712 15.582  3.971   1.00 25.60  ? 239 TYR A CB  1 
ATOM   1862  C  CG  . TYR A 1 239 ? -26.653 14.412  3.019   1.00 25.61  ? 239 TYR A CG  1 
ATOM   1863  C  CD1 . TYR A 1 239 ? -25.694 13.420  3.143   1.00 29.60  ? 239 TYR A CD1 1 
ATOM   1864  C  CD2 . TYR A 1 239 ? -27.570 14.308  1.986   1.00 24.99  ? 239 TYR A CD2 1 
ATOM   1865  C  CE1 . TYR A 1 239 ? -25.663 12.338  2.254   1.00 28.51  ? 239 TYR A CE1 1 
ATOM   1866  C  CE2 . TYR A 1 239 ? -27.545 13.245  1.099   1.00 25.41  ? 239 TYR A CE2 1 
ATOM   1867  C  CZ  . TYR A 1 239 ? -26.593 12.266  1.233   1.00 25.42  ? 239 TYR A CZ  1 
ATOM   1868  O  OH  . TYR A 1 239 ? -26.604 11.221  0.333   1.00 30.04  ? 239 TYR A OH  1 
ATOM   1869  N  N   . GLU A 1 240 ? -26.029 18.659  3.358   1.00 26.49  ? 240 GLU A N   1 
ATOM   1870  C  CA  . GLU A 1 240 ? -26.440 20.059  3.533   1.00 29.03  ? 240 GLU A CA  1 
ATOM   1871  C  C   . GLU A 1 240 ? -27.846 20.118  4.106   1.00 28.39  ? 240 GLU A C   1 
ATOM   1872  O  O   . GLU A 1 240 ? -28.717 19.392  3.644   1.00 28.78  ? 240 GLU A O   1 
ATOM   1873  C  CB  . GLU A 1 240 ? -26.422 20.782  2.193   1.00 28.08  ? 240 GLU A CB  1 
ATOM   1874  C  CG  . GLU A 1 240 ? -25.040 21.209  1.746   1.00 34.04  ? 240 GLU A CG  1 
ATOM   1875  C  CD  . GLU A 1 240 ? -24.523 22.496  2.365   1.00 40.02  ? 240 GLU A CD  1 
ATOM   1876  O  OE1 . GLU A 1 240 ? -25.275 23.483  2.390   1.00 40.09  ? 240 GLU A OE1 1 
ATOM   1877  O  OE2 . GLU A 1 240 ? -23.366 22.508  2.812   1.00 41.73  ? 240 GLU A OE2 1 
ATOM   1878  N  N   . PRO A 1 241 ? -28.088 20.977  5.099   1.00 23.82  ? 241 PRO A N   1 
ATOM   1879  C  CA  . PRO A 1 241 ? -29.451 21.171  5.609   1.00 29.11  ? 241 PRO A CA  1 
ATOM   1880  C  C   . PRO A 1 241 ? -30.448 21.376  4.479   1.00 26.06  ? 241 PRO A C   1 
ATOM   1881  O  O   . PRO A 1 241 ? -30.174 22.064  3.494   1.00 31.54  ? 241 PRO A O   1 
ATOM   1882  C  CB  . PRO A 1 241 ? -29.325 22.429  6.483   1.00 24.78  ? 241 PRO A CB  1 
ATOM   1883  C  CG  . PRO A 1 241 ? -27.887 22.486  6.860   1.00 24.03  ? 241 PRO A CG  1 
ATOM   1884  C  CD  . PRO A 1 241 ? -27.128 21.917  5.693   1.00 26.66  ? 241 PRO A CD  1 
ATOM   1885  N  N   . LEU A 1 242 ? -31.595 20.728  4.590   1.00 28.79  ? 242 LEU A N   1 
ATOM   1886  C  CA  . LEU A 1 242 ? -32.651 20.935  3.610   1.00 29.67  ? 242 LEU A CA  1 
ATOM   1887  C  C   . LEU A 1 242 ? -33.536 22.079  4.088   1.00 24.96  ? 242 LEU A C   1 
ATOM   1888  O  O   . LEU A 1 242 ? -33.965 22.104  5.246   1.00 27.66  ? 242 LEU A O   1 
ATOM   1889  C  CB  . LEU A 1 242 ? -33.462 19.660  3.387   1.00 21.90  ? 242 LEU A CB  1 
ATOM   1890  C  CG  . LEU A 1 242 ? -34.280 19.589  2.101   1.00 24.26  ? 242 LEU A CG  1 
ATOM   1891  C  CD1 . LEU A 1 242 ? -33.391 19.332  0.911   1.00 24.84  ? 242 LEU A CD1 1 
ATOM   1892  C  CD2 . LEU A 1 242 ? -35.375 18.516  2.199   1.00 24.25  ? 242 LEU A CD2 1 
ATOM   1893  N  N   . THR A 1 243 ? -33.785 23.034  3.214   1.00 28.95  ? 243 THR A N   1 
ATOM   1894  C  CA  . THR A 1 243 ? -34.589 24.188  3.574   1.00 27.53  ? 243 THR A CA  1 
ATOM   1895  C  C   . THR A 1 243 ? -35.957 24.099  2.919   1.00 28.43  ? 243 THR A C   1 
ATOM   1896  O  O   . THR A 1 243 ? -36.211 23.267  2.039   1.00 25.80  ? 243 THR A O   1 
ATOM   1897  C  CB  . THR A 1 243 ? -33.902 25.496  3.168   1.00 31.12  ? 243 THR A CB  1 
ATOM   1898  O  OG1 . THR A 1 243 ? -33.877 25.605  1.741   1.00 27.15  ? 243 THR A OG1 1 
ATOM   1899  C  CG2 . THR A 1 243 ? -32.503 25.539  3.704   1.00 30.03  ? 243 THR A CG2 1 
ATOM   1900  N  N   . GLN A 1 244 ? -36.844 24.985  3.377   1.00 26.86  ? 244 GLN A N   1 
ATOM   1901  C  CA  . GLN A 1 244 ? -38.166 25.084  2.773   1.00 29.53  ? 244 GLN A CA  1 
ATOM   1902  C  C   . GLN A 1 244 ? -38.071 25.537  1.321   1.00 29.39  ? 244 GLN A C   1 
ATOM   1903  O  O   . GLN A 1 244 ? -38.866 25.091  0.484   1.00 29.37  ? 244 GLN A O   1 
ATOM   1904  C  CB  . GLN A 1 244 ? -39.043 26.028  3.602   1.00 31.45  ? 244 GLN A CB  1 
ATOM   1905  C  CG  . GLN A 1 244 ? -40.483 26.124  3.143   1.00 28.86  ? 244 GLN A CG  1 
ATOM   1906  C  CD  . GLN A 1 244 ? -41.183 24.785  3.173   1.00 32.14  ? 244 GLN A CD  1 
ATOM   1907  O  OE1 . GLN A 1 244 ? -40.952 23.975  4.060   1.00 30.35  ? 244 GLN A OE1 1 
ATOM   1908  N  NE2 . GLN A 1 244 ? -42.023 24.536  2.175   1.00 37.87  ? 244 GLN A NE2 1 
ATOM   1909  N  N   . ASP A 1 245 ? -37.092 26.398  0.998   1.00 27.01  ? 245 ASP A N   1 
ATOM   1910  C  CA  . ASP A 1 245 ? -36.815 26.722  -0.402  1.00 28.74  ? 245 ASP A CA  1 
ATOM   1911  C  C   . ASP A 1 245 ? -36.469 25.464  -1.203  1.00 27.12  ? 245 ASP A C   1 
ATOM   1912  O  O   . ASP A 1 245 ? -36.837 25.339  -2.377  1.00 27.36  ? 245 ASP A O   1 
ATOM   1913  C  CB  . ASP A 1 245 ? -35.674 27.738  -0.502  1.00 32.46  ? 245 ASP A CB  1 
ATOM   1914  C  CG  . ASP A 1 245 ? -36.138 29.199  -0.342  1.00 36.13  ? 245 ASP A CG  1 
ATOM   1915  O  OD1 . ASP A 1 245 ? -37.218 29.459  0.221   1.00 36.69  ? 245 ASP A OD1 1 
ATOM   1916  O  OD2 . ASP A 1 245 ? -35.411 30.098  -0.799  1.00 38.34  ? 245 ASP A OD2 1 
ATOM   1917  N  N   . HIS A 1 246 ? -35.724 24.539  -0.597  1.00 25.94  ? 246 HIS A N   1 
ATOM   1918  C  CA  . HIS A 1 246 ? -35.396 23.290  -1.280  1.00 25.94  ? 246 HIS A CA  1 
ATOM   1919  C  C   . HIS A 1 246 ? -36.641 22.458  -1.511  1.00 27.14  ? 246 HIS A C   1 
ATOM   1920  O  O   . HIS A 1 246 ? -36.826 21.902  -2.595  1.00 23.96  ? 246 HIS A O   1 
ATOM   1921  C  CB  . HIS A 1 246 ? -34.394 22.485  -0.466  1.00 30.13  ? 246 HIS A CB  1 
ATOM   1922  C  CG  . HIS A 1 246 ? -33.021 23.063  -0.452  1.00 24.08  ? 246 HIS A CG  1 
ATOM   1923  N  ND1 . HIS A 1 246 ? -32.184 22.938  0.630   1.00 23.91  ? 246 HIS A ND1 1 
ATOM   1924  C  CD2 . HIS A 1 246 ? -32.332 23.753  -1.389  1.00 25.25  ? 246 HIS A CD2 1 
ATOM   1925  C  CE1 . HIS A 1 246 ? -31.036 23.534  0.362   1.00 28.86  ? 246 HIS A CE1 1 
ATOM   1926  N  NE2 . HIS A 1 246 ? -31.098 24.031  -0.860  1.00 23.58  ? 246 HIS A NE2 1 
ATOM   1927  N  N   . VAL A 1 247 ? -37.501 22.360  -0.496  1.00 25.05  ? 247 VAL A N   1 
ATOM   1928  C  CA  . VAL A 1 247 ? -38.762 21.652  -0.665  1.00 27.18  ? 247 VAL A CA  1 
ATOM   1929  C  C   . VAL A 1 247 ? -39.556 22.259  -1.810  1.00 28.98  ? 247 VAL A C   1 
ATOM   1930  O  O   . VAL A 1 247 ? -40.016 21.551  -2.714  1.00 31.21  ? 247 VAL A O   1 
ATOM   1931  C  CB  . VAL A 1 247 ? -39.573 21.674  0.645   1.00 30.74  ? 247 VAL A CB  1 
ATOM   1932  C  CG1 . VAL A 1 247 ? -40.885 20.950  0.458   1.00 25.61  ? 247 VAL A CG1 1 
ATOM   1933  C  CG2 . VAL A 1 247 ? -38.776 21.064  1.777   1.00 31.16  ? 247 VAL A CG2 1 
ATOM   1934  N  N   . ASP A 1 248 ? -39.682 23.584  -1.820  1.00 27.28  ? 248 ASP A N   1 
ATOM   1935  C  CA  . ASP A 1 248 ? -40.478 24.224  -2.860  1.00 27.61  ? 248 ASP A CA  1 
ATOM   1936  C  C   . ASP A 1 248 ? -39.876 23.988  -4.240  1.00 24.25  ? 248 ASP A C   1 
ATOM   1937  O  O   . ASP A 1 248 ? -40.603 23.761  -5.214  1.00 24.12  ? 248 ASP A O   1 
ATOM   1938  C  CB  . ASP A 1 248 ? -40.622 25.715  -2.560  1.00 27.43  ? 248 ASP A CB  1 
ATOM   1939  C  CG  . ASP A 1 248 ? -41.302 25.972  -1.224  1.00 37.70  ? 248 ASP A CG  1 
ATOM   1940  O  OD1 . ASP A 1 248 ? -42.102 25.101  -0.796  1.00 43.07  ? 248 ASP A OD1 1 
ATOM   1941  O  OD2 . ASP A 1 248 ? -41.052 27.038  -0.600  1.00 33.44  ? 248 ASP A OD2 1 
ATOM   1942  N  N   . ILE A 1 249 ? -38.548 24.042  -4.339  1.00 26.42  ? 249 ILE A N   1 
ATOM   1943  C  CA  . ILE A 1 249 ? -37.861 23.836  -5.612  1.00 27.97  ? 249 ILE A CA  1 
ATOM   1944  C  C   . ILE A 1 249 ? -38.121 22.430  -6.149  1.00 23.84  ? 249 ILE A C   1 
ATOM   1945  O  O   . ILE A 1 249 ? -38.344 22.240  -7.349  1.00 25.33  ? 249 ILE A O   1 
ATOM   1946  C  CB  . ILE A 1 249 ? -36.354 24.141  -5.438  1.00 30.66  ? 249 ILE A CB  1 
ATOM   1947  C  CG1 . ILE A 1 249 ? -36.128 25.663  -5.361  1.00 31.46  ? 249 ILE A CG1 1 
ATOM   1948  C  CG2 . ILE A 1 249 ? -35.504 23.503  -6.536  1.00 26.54  ? 249 ILE A CG2 1 
ATOM   1949  C  CD1 . ILE A 1 249 ? -34.790 26.052  -4.802  1.00 33.66  ? 249 ILE A CD1 1 
ATOM   1950  N  N   . LEU A 1 250 ? -38.171 21.435  -5.271  1.00 28.27  ? 250 LEU A N   1 
ATOM   1951  C  CA  . LEU A 1 250 ? -38.480 20.075  -5.700  1.00 24.57  ? 250 LEU A CA  1 
ATOM   1952  C  C   . LEU A 1 250 ? -39.947 19.875  -6.057  1.00 27.00  ? 250 LEU A C   1 
ATOM   1953  O  O   . LEU A 1 250 ? -40.295 18.786  -6.531  1.00 28.48  ? 250 LEU A O   1 
ATOM   1954  C  CB  . LEU A 1 250 ? -38.074 19.090  -4.605  1.00 24.21  ? 250 LEU A CB  1 
ATOM   1955  C  CG  . LEU A 1 250 ? -36.563 18.878  -4.477  1.00 25.00  ? 250 LEU A CG  1 
ATOM   1956  C  CD1 . LEU A 1 250 ? -36.240 18.184  -3.169  1.00 18.37  ? 250 LEU A CD1 1 
ATOM   1957  C  CD2 . LEU A 1 250 ? -36.066 18.053  -5.676  1.00 19.88  ? 250 LEU A CD2 1 
ATOM   1958  N  N   . GLY A 1 251 ? -40.790 20.899  -5.886  1.00 29.74  ? 251 GLY A N   1 
ATOM   1959  C  CA  . GLY A 1 251 ? -42.216 20.826  -6.143  1.00 27.70  ? 251 GLY A CA  1 
ATOM   1960  C  C   . GLY A 1 251 ? -42.655 20.226  -7.468  1.00 27.16  ? 251 GLY A C   1 
ATOM   1961  O  O   . GLY A 1 251 ? -43.418 19.258  -7.494  1.00 29.99  ? 251 GLY A O   1 
ATOM   1962  N  N   . PRO A 1 252 ? -42.202 20.793  -8.592  1.00 29.54  ? 252 PRO A N   1 
ATOM   1963  C  CA  . PRO A 1 252 ? -42.593 20.229  -9.902  1.00 29.61  ? 252 PRO A CA  1 
ATOM   1964  C  C   . PRO A 1 252 ? -42.260 18.748  -10.048 1.00 27.90  ? 252 PRO A C   1 
ATOM   1965  O  O   . PRO A 1 252 ? -43.064 17.977  -10.591 1.00 29.36  ? 252 PRO A O   1 
ATOM   1966  C  CB  . PRO A 1 252 ? -41.805 21.094  -10.900 1.00 25.35  ? 252 PRO A CB  1 
ATOM   1967  C  CG  . PRO A 1 252 ? -41.633 22.395  -10.198 1.00 24.80  ? 252 PRO A CG  1 
ATOM   1968  C  CD  . PRO A 1 252 ? -41.471 22.065  -8.734  1.00 32.69  ? 252 PRO A CD  1 
ATOM   1969  N  N   . LEU A 1 253 ? -41.092 18.326  -9.578  1.00 28.60  ? 253 LEU A N   1 
ATOM   1970  C  CA  . LEU A 1 253 ? -40.770 16.907  -9.622  1.00 27.32  ? 253 LEU A CA  1 
ATOM   1971  C  C   . LEU A 1 253 ? -41.704 16.117  -8.714  1.00 30.23  ? 253 LEU A C   1 
ATOM   1972  O  O   . LEU A 1 253 ? -42.057 14.968  -9.022  1.00 27.37  ? 253 LEU A O   1 
ATOM   1973  C  CB  . LEU A 1 253 ? -39.314 16.685  -9.207  1.00 20.80  ? 253 LEU A CB  1 
ATOM   1974  C  CG  . LEU A 1 253 ? -38.188 17.088  -10.169 1.00 24.96  ? 253 LEU A CG  1 
ATOM   1975  C  CD1 . LEU A 1 253 ? -36.799 16.945  -9.524  1.00 21.55  ? 253 LEU A CD1 1 
ATOM   1976  C  CD2 . LEU A 1 253 ? -38.261 16.276  -11.475 1.00 26.02  ? 253 LEU A CD2 1 
ATOM   1977  N  N   . SER A 1 254 ? -42.129 16.732  -7.606  1.00 30.72  ? 254 SER A N   1 
ATOM   1978  C  CA  . SER A 1 254 ? -43.043 16.076  -6.678  1.00 31.59  ? 254 SER A CA  1 
ATOM   1979  C  C   . SER A 1 254 ? -44.397 15.833  -7.328  1.00 37.38  ? 254 SER A C   1 
ATOM   1980  O  O   . SER A 1 254 ? -44.974 14.741  -7.195  1.00 36.85  ? 254 SER A O   1 
ATOM   1981  C  CB  . SER A 1 254 ? -43.180 16.933  -5.414  1.00 30.19  ? 254 SER A CB  1 
ATOM   1982  O  OG  . SER A 1 254 ? -44.072 16.367  -4.473  1.00 28.63  ? 254 SER A OG  1 
ATOM   1983  N  N   . ALA A 1 255 ? -44.893 16.828  -8.076  1.00 34.79  ? 255 ALA A N   1 
ATOM   1984  C  CA  . ALA A 1 255 ? -46.189 16.724  -8.742  1.00 34.07  ? 255 ALA A CA  1 
ATOM   1985  C  C   . ALA A 1 255 ? -46.143 15.733  -9.902  1.00 35.88  ? 255 ALA A C   1 
ATOM   1986  O  O   . ALA A 1 255 ? -47.113 15.009  -10.151 1.00 34.98  ? 255 ALA A O   1 
ATOM   1987  C  CB  . ALA A 1 255 ? -46.625 18.110  -9.237  1.00 35.54  ? 255 ALA A CB  1 
ATOM   1988  N  N   . GLN A 1 256 ? -45.038 15.716  -10.641 1.00 32.34  ? 256 GLN A N   1 
ATOM   1989  C  CA  . GLN A 1 256 ? -44.897 14.799  -11.762 1.00 31.41  ? 256 GLN A CA  1 
ATOM   1990  C  C   . GLN A 1 256 ? -44.924 13.336  -11.317 1.00 37.93  ? 256 GLN A C   1 
ATOM   1991  O  O   . GLN A 1 256 ? -45.358 12.461  -12.078 1.00 43.55  ? 256 GLN A O   1 
ATOM   1992  C  CB  . GLN A 1 256 ? -43.606 15.130  -12.501 1.00 32.91  ? 256 GLN A CB  1 
ATOM   1993  C  CG  . GLN A 1 256 ? -43.160 14.086  -13.481 1.00 43.23  ? 256 GLN A CG  1 
ATOM   1994  C  CD  . GLN A 1 256 ? -42.061 14.582  -14.392 1.00 49.55  ? 256 GLN A CD  1 
ATOM   1995  O  OE1 . GLN A 1 256 ? -41.633 15.743  -14.311 1.00 51.22  ? 256 GLN A OE1 1 
ATOM   1996  N  NE2 . GLN A 1 256 ? -41.581 13.697  -15.260 1.00 50.77  ? 256 GLN A NE2 1 
ATOM   1997  N  N   . THR A 1 257 ? -44.434 13.036  -10.110 1.00 36.71  ? 257 THR A N   1 
ATOM   1998  C  CA  . THR A 1 257 ? -44.433 11.663  -9.610  1.00 33.23  ? 257 THR A CA  1 
ATOM   1999  C  C   . THR A 1 257 ? -45.578 11.354  -8.641  1.00 32.17  ? 257 THR A C   1 
ATOM   2000  O  O   . THR A 1 257 ? -45.867 10.173  -8.401  1.00 29.04  ? 257 THR A O   1 
ATOM   2001  C  CB  . THR A 1 257 ? -43.086 11.341  -8.939  1.00 29.57  ? 257 THR A CB  1 
ATOM   2002  O  OG1 . THR A 1 257 ? -42.833 12.270  -7.862  1.00 26.85  ? 257 THR A OG1 1 
ATOM   2003  C  CG2 . THR A 1 257 ? -41.974 11.429  -9.969  1.00 24.54  ? 257 THR A CG2 1 
ATOM   2004  N  N   . GLY A 1 258 ? -46.206 12.371  -8.046  1.00 28.43  ? 258 GLY A N   1 
ATOM   2005  C  CA  . GLY A 1 258 ? -47.200 12.082  -7.034  1.00 27.50  ? 258 GLY A CA  1 
ATOM   2006  C  C   . GLY A 1 258 ? -46.619 11.570  -5.734  1.00 33.03  ? 258 GLY A C   1 
ATOM   2007  O  O   . GLY A 1 258 ? -47.326 10.912  -4.964  1.00 30.68  ? 258 GLY A O   1 
ATOM   2008  N  N   . ILE A 1 259 ? -45.341 11.853  -5.476  1.00 30.73  ? 259 ILE A N   1 
ATOM   2009  C  CA  . ILE A 1 259 ? -44.662 11.511  -4.231  1.00 29.54  ? 259 ILE A CA  1 
ATOM   2010  C  C   . ILE A 1 259 ? -44.354 12.815  -3.519  1.00 30.50  ? 259 ILE A C   1 
ATOM   2011  O  O   . ILE A 1 259 ? -43.602 13.648  -4.047  1.00 34.34  ? 259 ILE A O   1 
ATOM   2012  C  CB  . ILE A 1 259 ? -43.360 10.740  -4.488  1.00 27.58  ? 259 ILE A CB  1 
ATOM   2013  C  CG1 . ILE A 1 259 ? -43.630 9.481   -5.294  1.00 25.79  ? 259 ILE A CG1 1 
ATOM   2014  C  CG2 . ILE A 1 259 ? -42.690 10.417  -3.158  1.00 25.52  ? 259 ILE A CG2 1 
ATOM   2015  C  CD1 . ILE A 1 259 ? -42.381 8.895   -5.880  1.00 23.22  ? 259 ILE A CD1 1 
ATOM   2016  N  N   . ALA A 1 260 ? -44.941 13.018  -2.344  1.00 27.70  ? 260 ALA A N   1 
ATOM   2017  C  CA  . ALA A 1 260 ? -44.664 14.248  -1.616  1.00 27.66  ? 260 ALA A CA  1 
ATOM   2018  C  C   . ALA A 1 260 ? -43.181 14.323  -1.252  1.00 25.84  ? 260 ALA A C   1 
ATOM   2019  O  O   . ALA A 1 260 ? -42.511 13.303  -1.061  1.00 27.86  ? 260 ALA A O   1 
ATOM   2020  C  CB  . ALA A 1 260 ? -45.538 14.345  -0.370  1.00 25.35  ? 260 ALA A CB  1 
ATOM   2021  N  N   . VAL A 1 261 ? -42.661 15.556  -1.185  1.00 30.27  ? 261 VAL A N   1 
ATOM   2022  C  CA  . VAL A 1 261 ? -41.229 15.756  -0.966  1.00 21.98  ? 261 VAL A CA  1 
ATOM   2023  C  C   . VAL A 1 261 ? -40.820 15.201  0.393   1.00 23.10  ? 261 VAL A C   1 
ATOM   2024  O  O   . VAL A 1 261 ? -39.764 14.565  0.528   1.00 25.54  ? 261 VAL A O   1 
ATOM   2025  C  CB  . VAL A 1 261 ? -40.849 17.246  -1.135  1.00 23.85  ? 261 VAL A CB  1 
ATOM   2026  C  CG1 . VAL A 1 261 ? -39.432 17.507  -0.646  1.00 21.22  ? 261 VAL A CG1 1 
ATOM   2027  C  CG2 . VAL A 1 261 ? -40.940 17.666  -2.590  1.00 18.26  ? 261 VAL A CG2 1 
ATOM   2028  N  N   . LEU A 1 262 ? -41.656 15.402  1.415   1.00 20.30  ? 262 LEU A N   1 
ATOM   2029  C  CA  . LEU A 1 262 ? -41.332 14.841  2.719   1.00 25.42  ? 262 LEU A CA  1 
ATOM   2030  C  C   . LEU A 1 262 ? -41.379 13.311  2.723   1.00 24.54  ? 262 LEU A C   1 
ATOM   2031  O  O   . LEU A 1 262 ? -40.671 12.676  3.513   1.00 23.52  ? 262 LEU A O   1 
ATOM   2032  C  CB  . LEU A 1 262 ? -42.271 15.409  3.783   1.00 26.83  ? 262 LEU A CB  1 
ATOM   2033  C  CG  . LEU A 1 262 ? -41.966 16.878  4.087   1.00 26.21  ? 262 LEU A CG  1 
ATOM   2034  C  CD1 . LEU A 1 262 ? -42.981 17.448  5.056   1.00 26.55  ? 262 LEU A CD1 1 
ATOM   2035  C  CD2 . LEU A 1 262 ? -40.582 16.962  4.671   1.00 26.45  ? 262 LEU A CD2 1 
ATOM   2036  N  N   . ASP A 1 263 ? -42.181 12.701  1.847   1.00 24.66  ? 263 ASP A N   1 
ATOM   2037  C  CA  . ASP A 1 263 ? -42.123 11.251  1.706   1.00 26.97  ? 263 ASP A CA  1 
ATOM   2038  C  C   . ASP A 1 263 ? -40.817 10.823  1.051   1.00 26.94  ? 263 ASP A C   1 
ATOM   2039  O  O   . ASP A 1 263 ? -40.145 9.899   1.536   1.00 23.99  ? 263 ASP A O   1 
ATOM   2040  C  CB  . ASP A 1 263 ? -43.347 10.748  0.934   1.00 26.73  ? 263 ASP A CB  1 
ATOM   2041  C  CG  . ASP A 1 263 ? -44.635 10.858  1.760   1.00 30.63  ? 263 ASP A CG  1 
ATOM   2042  O  OD1 . ASP A 1 263 ? -44.569 11.366  2.908   1.00 30.18  ? 263 ASP A OD1 1 
ATOM   2043  O  OD2 . ASP A 1 263 ? -45.704 10.429  1.281   1.00 29.71  ? 263 ASP A OD2 1 
ATOM   2044  N  N   . MET A 1 264 ? -40.396 11.531  -0.002  1.00 25.23  ? 264 MET A N   1 
ATOM   2045  C  CA  . MET A 1 264 ? -39.107 11.203  -0.599  1.00 23.74  ? 264 MET A CA  1 
ATOM   2046  C  C   . MET A 1 264 ? -37.980 11.408  0.405   1.00 24.56  ? 264 MET A C   1 
ATOM   2047  O  O   . MET A 1 264 ? -37.019 10.621  0.434   1.00 21.95  ? 264 MET A O   1 
ATOM   2048  C  CB  . MET A 1 264 ? -38.863 12.036  -1.851  1.00 18.04  ? 264 MET A CB  1 
ATOM   2049  C  CG  . MET A 1 264 ? -37.637 11.593  -2.617  1.00 25.38  ? 264 MET A CG  1 
ATOM   2050  S  SD  . MET A 1 264 ? -37.849 9.945   -3.354  1.00 23.74  ? 264 MET A SD  1 
ATOM   2051  C  CE  . MET A 1 264 ? -38.817 10.380  -4.784  1.00 17.73  ? 264 MET A CE  1 
ATOM   2052  N  N   . CYS A 1 265 ? -38.098 12.437  1.264   1.00 17.53  ? 265 CYS A N   1 
ATOM   2053  C  CA  . CYS A 1 265 ? -37.096 12.628  2.310   1.00 20.31  ? 265 CYS A CA  1 
ATOM   2054  C  C   . CYS A 1 265 ? -37.009 11.428  3.242   1.00 21.78  ? 265 CYS A C   1 
ATOM   2055  O  O   . CYS A 1 265 ? -35.915 11.063  3.682   1.00 21.87  ? 265 CYS A O   1 
ATOM   2056  C  CB  . CYS A 1 265 ? -37.387 13.891  3.113   1.00 27.05  ? 265 CYS A CB  1 
ATOM   2057  S  SG  . CYS A 1 265 ? -36.964 15.365  2.212   1.00 23.16  ? 265 CYS A SG  1 
ATOM   2058  N  N   . ALA A 1 266 ? -38.155 10.808  3.566   1.00 22.91  ? 266 ALA A N   1 
ATOM   2059  C  CA  . ALA A 1 266 ? -38.128 9.600   4.384   1.00 21.20  ? 266 ALA A CA  1 
ATOM   2060  C  C   . ALA A 1 266 ? -37.409 8.448   3.673   1.00 22.78  ? 266 ALA A C   1 
ATOM   2061  O  O   . ALA A 1 266 ? -36.758 7.621   4.329   1.00 25.96  ? 266 ALA A O   1 
ATOM   2062  C  CB  . ALA A 1 266 ? -39.551 9.208   4.758   1.00 30.54  ? 266 ALA A CB  1 
ATOM   2063  N  N   . SER A 1 267 ? -37.503 8.380   2.340   1.00 21.73  ? 267 SER A N   1 
ATOM   2064  C  CA  . SER A 1 267 ? -36.747 7.376   1.591   1.00 24.99  ? 267 SER A CA  1 
ATOM   2065  C  C   . SER A 1 267 ? -35.257 7.678   1.614   1.00 22.05  ? 267 SER A C   1 
ATOM   2066  O  O   . SER A 1 267 ? -34.440 6.771   1.791   1.00 22.80  ? 267 SER A O   1 
ATOM   2067  C  CB  . SER A 1 267 ? -37.233 7.305   0.146   1.00 21.56  ? 267 SER A CB  1 
ATOM   2068  O  OG  . SER A 1 267 ? -38.496 6.686   0.082   1.00 25.73  ? 267 SER A OG  1 
ATOM   2069  N  N   . LEU A 1 268 ? -34.875 8.944   1.450   1.00 24.45  ? 268 LEU A N   1 
ATOM   2070  C  CA  . LEU A 1 268 ? -33.455 9.265   1.547   1.00 21.95  ? 268 LEU A CA  1 
ATOM   2071  C  C   . LEU A 1 268 ? -32.926 8.962   2.943   1.00 21.22  ? 268 LEU A C   1 
ATOM   2072  O  O   . LEU A 1 268 ? -31.855 8.364   3.096   1.00 22.44  ? 268 LEU A O   1 
ATOM   2073  C  CB  . LEU A 1 268 ? -33.211 10.739  1.172   1.00 18.39  ? 268 LEU A CB  1 
ATOM   2074  C  CG  . LEU A 1 268 ? -31.796 11.327  1.314   1.00 20.56  ? 268 LEU A CG  1 
ATOM   2075  C  CD1 . LEU A 1 268 ? -30.726 10.495  0.620   1.00 18.79  ? 268 LEU A CD1 1 
ATOM   2076  C  CD2 . LEU A 1 268 ? -31.758 12.747  0.743   1.00 15.75  ? 268 LEU A CD2 1 
ATOM   2077  N  N   . LYS A 1 269 ? -33.689 9.327   3.968   1.00 20.02  ? 269 LYS A N   1 
ATOM   2078  C  CA  . LYS A 1 269 ? -33.317 9.038   5.348   1.00 28.33  ? 269 LYS A CA  1 
ATOM   2079  C  C   . LYS A 1 269 ? -33.032 7.548   5.571   1.00 28.58  ? 269 LYS A C   1 
ATOM   2080  O  O   . LYS A 1 269 ? -31.991 7.186   6.127   1.00 28.49  ? 269 LYS A O   1 
ATOM   2081  C  CB  . LYS A 1 269 ? -34.435 9.547   6.266   1.00 35.13  ? 269 LYS A CB  1 
ATOM   2082  C  CG  . LYS A 1 269 ? -34.323 9.258   7.771   1.00 36.13  ? 269 LYS A CG  1 
ATOM   2083  C  CD  . LYS A 1 269 ? -35.219 10.270  8.481   1.00 32.26  ? 269 LYS A CD  1 
ATOM   2084  C  CE  . LYS A 1 269 ? -35.903 9.715   9.711   1.00 40.36  ? 269 LYS A CE  1 
ATOM   2085  N  NZ  . LYS A 1 269 ? -37.074 10.589  10.083  1.00 41.82  ? 269 LYS A NZ  1 
ATOM   2086  N  N   . GLU A 1 270 ? -33.905 6.660   5.094   1.00 25.65  ? 270 GLU A N   1 
ATOM   2087  C  CA  . GLU A 1 270 ? -33.621 5.241   5.306   1.00 35.84  ? 270 GLU A CA  1 
ATOM   2088  C  C   . GLU A 1 270 ? -32.426 4.780   4.473   1.00 30.32  ? 270 GLU A C   1 
ATOM   2089  O  O   . GLU A 1 270 ? -31.632 3.944   4.919   1.00 29.80  ? 270 GLU A O   1 
ATOM   2090  C  CB  . GLU A 1 270 ? -34.849 4.375   5.005   1.00 34.81  ? 270 GLU A CB  1 
ATOM   2091  C  CG  . GLU A 1 270 ? -36.002 4.499   5.999   1.00 39.25  ? 270 GLU A CG  1 
ATOM   2092  C  CD  . GLU A 1 270 ? -35.616 4.137   7.436   1.00 53.40  ? 270 GLU A CD  1 
ATOM   2093  O  OE1 . GLU A 1 270 ? -34.991 3.069   7.647   1.00 51.35  ? 270 GLU A OE1 1 
ATOM   2094  O  OE2 . GLU A 1 270 ? -35.981 4.908   8.360   1.00 56.66  ? 270 GLU A OE2 1 
ATOM   2095  N  N   . LEU A 1 271 ? -32.286 5.293   3.257   1.00 28.11  ? 271 LEU A N   1 
ATOM   2096  C  CA  . LEU A 1 271 ? -31.083 4.995   2.490   1.00 27.88  ? 271 LEU A CA  1 
ATOM   2097  C  C   . LEU A 1 271 ? -29.829 5.414   3.254   1.00 33.13  ? 271 LEU A C   1 
ATOM   2098  O  O   . LEU A 1 271 ? -28.845 4.666   3.305   1.00 31.59  ? 271 LEU A O   1 
ATOM   2099  C  CB  . LEU A 1 271 ? -31.150 5.694   1.137   1.00 24.58  ? 271 LEU A CB  1 
ATOM   2100  C  CG  . LEU A 1 271 ? -32.067 4.982   0.150   1.00 21.57  ? 271 LEU A CG  1 
ATOM   2101  C  CD1 . LEU A 1 271 ? -32.234 5.832   -1.114  1.00 28.95  ? 271 LEU A CD1 1 
ATOM   2102  C  CD2 . LEU A 1 271 ? -31.535 3.606   -0.191  1.00 26.63  ? 271 LEU A CD2 1 
ATOM   2103  N  N   . LEU A 1 272 ? -29.843 6.610   3.858   1.00 32.97  ? 272 LEU A N   1 
ATOM   2104  C  CA  . LEU A 1 272 ? -28.659 7.078   4.571   1.00 27.19  ? 272 LEU A CA  1 
ATOM   2105  C  C   . LEU A 1 272 ? -28.326 6.175   5.748   1.00 30.24  ? 272 LEU A C   1 
ATOM   2106  O  O   . LEU A 1 272 ? -27.148 5.904   6.022   1.00 29.53  ? 272 LEU A O   1 
ATOM   2107  C  CB  . LEU A 1 272 ? -28.847 8.524   5.030   1.00 25.52  ? 272 LEU A CB  1 
ATOM   2108  C  CG  . LEU A 1 272 ? -28.668 9.529   3.882   1.00 27.79  ? 272 LEU A CG  1 
ATOM   2109  C  CD1 . LEU A 1 272 ? -28.997 10.932  4.324   1.00 27.22  ? 272 LEU A CD1 1 
ATOM   2110  C  CD2 . LEU A 1 272 ? -27.248 9.468   3.297   1.00 30.89  ? 272 LEU A CD2 1 
ATOM   2111  N  N   . GLN A 1 273 ? -29.344 5.708   6.463   1.00 31.50  ? 273 GLN A N   1 
ATOM   2112  C  CA  . GLN A 1 273 ? -29.078 4.976   7.692   1.00 31.14  ? 273 GLN A CA  1 
ATOM   2113  C  C   . GLN A 1 273 ? -28.744 3.517   7.410   1.00 29.68  ? 273 GLN A C   1 
ATOM   2114  O  O   . GLN A 1 273 ? -27.872 2.952   8.072   1.00 31.52  ? 273 GLN A O   1 
ATOM   2115  C  CB  . GLN A 1 273 ? -30.293 5.085   8.622   1.00 35.47  ? 273 GLN A CB  1 
ATOM   2116  C  CG  . GLN A 1 273 ? -30.485 6.488   9.224   1.00 29.46  ? 273 GLN A CG  1 
ATOM   2117  C  CD  . GLN A 1 273 ? -31.776 6.624   10.036  1.00 37.58  ? 273 GLN A CD  1 
ATOM   2118  O  OE1 . GLN A 1 273 ? -32.763 5.925   9.781   1.00 38.41  ? 273 GLN A OE1 1 
ATOM   2119  N  NE2 . GLN A 1 273 ? -31.795 7.577   10.970  1.00 36.56  ? 273 GLN A NE2 1 
ATOM   2120  N  N   . ASN A 1 274 ? -29.360 2.914   6.397   1.00 29.77  ? 274 ASN A N   1 
ATOM   2121  C  CA  . ASN A 1 274 ? -29.177 1.495   6.117   1.00 34.90  ? 274 ASN A CA  1 
ATOM   2122  C  C   . ASN A 1 274 ? -28.450 1.189   4.809   1.00 36.23  ? 274 ASN A C   1 
ATOM   2123  O  O   . ASN A 1 274 ? -28.323 0.012   4.450   1.00 38.77  ? 274 ASN A O   1 
ATOM   2124  C  CB  . ASN A 1 274 ? -30.538 0.789   6.131   1.00 32.10  ? 274 ASN A CB  1 
ATOM   2125  C  CG  . ASN A 1 274 ? -31.333 1.111   7.365   1.00 34.57  ? 274 ASN A CG  1 
ATOM   2126  O  OD1 . ASN A 1 274 ? -32.483 1.513   7.286   1.00 44.24  ? 274 ASN A OD1 1 
ATOM   2127  N  ND2 . ASN A 1 274 ? -30.726 0.916   8.525   1.00 43.36  ? 274 ASN A ND2 1 
ATOM   2128  N  N   . GLY A 1 275 ? -27.976 2.185   4.087   1.00 26.38  ? 275 GLY A N   1 
ATOM   2129  C  CA  . GLY A 1 275 ? -27.314 1.843   2.848   1.00 29.87  ? 275 GLY A CA  1 
ATOM   2130  C  C   . GLY A 1 275 ? -28.264 1.299   1.791   1.00 35.11  ? 275 GLY A C   1 
ATOM   2131  O  O   . GLY A 1 275 ? -29.487 1.399   1.891   1.00 36.69  ? 275 GLY A O   1 
ATOM   2132  N  N   . MET A 1 276 ? -27.666 0.731   0.739   1.00 34.69  ? 276 MET A N   1 
ATOM   2133  C  CA  . MET A 1 276 ? -28.426 0.291   -0.425  1.00 32.67  ? 276 MET A CA  1 
ATOM   2134  C  C   . MET A 1 276 ? -28.551 -1.227  -0.562  1.00 37.50  ? 276 MET A C   1 
ATOM   2135  O  O   . MET A 1 276 ? -29.302 -1.691  -1.429  1.00 37.47  ? 276 MET A O   1 
ATOM   2136  C  CB  . MET A 1 276 ? -27.788 0.892   -1.690  1.00 36.15  ? 276 MET A CB  1 
ATOM   2137  C  CG  . MET A 1 276 ? -28.004 2.406   -1.785  1.00 35.01  ? 276 MET A CG  1 
ATOM   2138  S  SD  . MET A 1 276 ? -27.480 3.202   -3.317  1.00 55.60  ? 276 MET A SD  1 
ATOM   2139  C  CE  . MET A 1 276 ? -28.407 2.316   -4.546  1.00 32.08  ? 276 MET A CE  1 
ATOM   2140  N  N   . ASN A 1 277 ? -27.890 -2.004  0.298   1.00 34.25  ? 277 ASN A N   1 
ATOM   2141  C  CA  . ASN A 1 277 ? -28.051 -3.454  0.336   1.00 43.30  ? 277 ASN A CA  1 
ATOM   2142  C  C   . ASN A 1 277 ? -27.729 -4.077  -1.017  1.00 44.12  ? 277 ASN A C   1 
ATOM   2143  O  O   . ASN A 1 277 ? -28.498 -4.880  -1.558  1.00 43.85  ? 277 ASN A O   1 
ATOM   2144  C  CB  . ASN A 1 277 ? -29.455 -3.857  0.794   1.00 50.45  ? 277 ASN A CB  1 
ATOM   2145  C  CG  . ASN A 1 277 ? -29.695 -3.539  2.242   1.00 53.64  ? 277 ASN A CG  1 
ATOM   2146  O  OD1 . ASN A 1 277 ? -28.810 -3.738  3.082   1.00 57.00  ? 277 ASN A OD1 1 
ATOM   2147  N  ND2 . ASN A 1 277 ? -30.893 -3.045  2.555   1.00 50.37  ? 277 ASN A ND2 1 
ATOM   2148  N  N   . GLY A 1 278 ? -26.602 -3.656  -1.590  1.00 38.24  ? 278 GLY A N   1 
ATOM   2149  C  CA  . GLY A 1 278 ? -26.160 -4.201  -2.853  1.00 34.77  ? 278 GLY A CA  1 
ATOM   2150  C  C   . GLY A 1 278 ? -27.026 -3.885  -4.049  1.00 37.67  ? 278 GLY A C   1 
ATOM   2151  O  O   . GLY A 1 278 ? -26.729 -4.378  -5.141  1.00 39.61  ? 278 GLY A O   1 
ATOM   2152  N  N   . ARG A 1 279 ? -28.084 -3.087  -3.889  1.00 37.63  ? 279 ARG A N   1 
ATOM   2153  C  CA  . ARG A 1 279 ? -28.896 -2.639  -5.009  1.00 32.72  ? 279 ARG A CA  1 
ATOM   2154  C  C   . ARG A 1 279 ? -28.291 -1.356  -5.599  1.00 35.82  ? 279 ARG A C   1 
ATOM   2155  O  O   . ARG A 1 279 ? -27.371 -0.761  -5.037  1.00 29.68  ? 279 ARG A O   1 
ATOM   2156  C  CB  . ARG A 1 279 ? -30.345 -2.412  -4.565  1.00 31.08  ? 279 ARG A CB  1 
ATOM   2157  C  CG  . ARG A 1 279 ? -31.223 -3.640  -4.731  1.00 38.40  ? 279 ARG A CG  1 
ATOM   2158  C  CD  . ARG A 1 279 ? -32.541 -3.513  -3.997  1.00 40.02  ? 279 ARG A CD  1 
ATOM   2159  N  NE  . ARG A 1 279 ? -32.357 -3.210  -2.583  1.00 41.25  ? 279 ARG A NE  1 
ATOM   2160  C  CZ  . ARG A 1 279 ? -33.349 -2.922  -1.751  1.00 36.38  ? 279 ARG A CZ  1 
ATOM   2161  N  NH1 . ARG A 1 279 ? -34.611 -2.952  -2.150  1.00 34.33  ? 279 ARG A NH1 1 
ATOM   2162  N  NH2 . ARG A 1 279 ? -33.065 -2.563  -0.498  1.00 33.89  ? 279 ARG A NH2 1 
ATOM   2163  N  N   . THR A 1 280 ? -28.814 -0.927  -6.748  1.00 32.24  ? 280 THR A N   1 
ATOM   2164  C  CA  . THR A 1 280 ? -28.364 0.304   -7.378  1.00 27.70  ? 280 THR A CA  1 
ATOM   2165  C  C   . THR A 1 280 ? -29.575 1.137   -7.756  1.00 28.96  ? 280 THR A C   1 
ATOM   2166  O  O   . THR A 1 280 ? -30.711 0.661   -7.765  1.00 26.65  ? 280 THR A O   1 
ATOM   2167  C  CB  . THR A 1 280 ? -27.509 0.095   -8.648  1.00 31.18  ? 280 THR A CB  1 
ATOM   2168  O  OG1 . THR A 1 280 ? -28.339 -0.353  -9.736  1.00 30.73  ? 280 THR A OG1 1 
ATOM   2169  C  CG2 . THR A 1 280 ? -26.371 -0.882  -8.404  1.00 26.02  ? 280 THR A CG2 1 
ATOM   2170  N  N   . ILE A 1 281 ? -29.306 2.405   -8.052  1.00 26.68  ? 281 ILE A N   1 
ATOM   2171  C  CA  . ILE A 1 281 ? -30.310 3.365   -8.479  1.00 23.20  ? 281 ILE A CA  1 
ATOM   2172  C  C   . ILE A 1 281 ? -29.741 4.071   -9.687  1.00 24.86  ? 281 ILE A C   1 
ATOM   2173  O  O   . ILE A 1 281 ? -28.701 4.735   -9.582  1.00 26.90  ? 281 ILE A O   1 
ATOM   2174  C  CB  . ILE A 1 281 ? -30.637 4.386   -7.380  1.00 28.04  ? 281 ILE A CB  1 
ATOM   2175  C  CG1 . ILE A 1 281 ? -31.144 3.684   -6.128  1.00 24.15  ? 281 ILE A CG1 1 
ATOM   2176  C  CG2 . ILE A 1 281 ? -31.669 5.391   -7.883  1.00 26.57  ? 281 ILE A CG2 1 
ATOM   2177  C  CD1 . ILE A 1 281 ? -31.339 4.610   -4.951  1.00 28.14  ? 281 ILE A CD1 1 
ATOM   2178  N  N   . LEU A 1 282 ? -30.398 3.913   -10.831 1.00 31.24  ? 282 LEU A N   1 
ATOM   2179  C  CA  . LEU A 1 282 ? -29.904 4.480   -12.081 1.00 28.37  ? 282 LEU A CA  1 
ATOM   2180  C  C   . LEU A 1 282 ? -28.453 4.077   -12.318 1.00 29.32  ? 282 LEU A C   1 
ATOM   2181  O  O   . LEU A 1 282 ? -27.603 4.899   -12.689 1.00 27.33  ? 282 LEU A O   1 
ATOM   2182  C  CB  . LEU A 1 282 ? -30.076 6.002   -12.094 1.00 28.93  ? 282 LEU A CB  1 
ATOM   2183  C  CG  . LEU A 1 282 ? -31.553 6.398   -12.143 1.00 27.71  ? 282 LEU A CG  1 
ATOM   2184  C  CD1 . LEU A 1 282 ? -31.723 7.882   -11.959 1.00 25.71  ? 282 LEU A CD1 1 
ATOM   2185  C  CD2 . LEU A 1 282 ? -32.165 5.923   -13.472 1.00 22.06  ? 282 LEU A CD2 1 
ATOM   2186  N  N   . GLY A 1 283 ? -28.169 2.798   -12.072 1.00 25.80  ? 283 GLY A N   1 
ATOM   2187  C  CA  . GLY A 1 283 ? -26.868 2.238   -12.371 1.00 27.04  ? 283 GLY A CA  1 
ATOM   2188  C  C   . GLY A 1 283 ? -25.761 2.767   -11.503 1.00 28.50  ? 283 GLY A C   1 
ATOM   2189  O  O   . GLY A 1 283 ? -24.579 2.671   -11.865 1.00 32.06  ? 283 GLY A O   1 
ATOM   2190  N  N   . SER A 1 284 ? -26.109 3.324   -10.360 1.00 22.86  ? 284 SER A N   1 
ATOM   2191  C  CA  . SER A 1 284 ? -25.134 3.912   -9.469  1.00 27.44  ? 284 SER A CA  1 
ATOM   2192  C  C   . SER A 1 284 ? -25.299 3.269   -8.110  1.00 28.00  ? 284 SER A C   1 
ATOM   2193  O  O   . SER A 1 284 ? -26.425 3.073   -7.655  1.00 29.45  ? 284 SER A O   1 
ATOM   2194  C  CB  . SER A 1 284 ? -25.328 5.428   -9.370  1.00 24.68  ? 284 SER A CB  1 
ATOM   2195  O  OG  . SER A 1 284 ? -24.408 5.990   -8.464  1.00 37.27  ? 284 SER A OG  1 
ATOM   2196  N  N   . ALA A 1 285 ? -24.181 2.945   -7.469  1.00 23.66  ? 285 ALA A N   1 
ATOM   2197  C  CA  . ALA A 1 285 ? -24.209 2.354   -6.140  1.00 31.97  ? 285 ALA A CA  1 
ATOM   2198  C  C   . ALA A 1 285 ? -24.064 3.391   -5.024  1.00 34.99  ? 285 ALA A C   1 
ATOM   2199  O  O   . ALA A 1 285 ? -24.125 3.032   -3.844  1.00 33.64  ? 285 ALA A O   1 
ATOM   2200  C  CB  . ALA A 1 285 ? -23.121 1.280   -6.016  1.00 32.55  ? 285 ALA A CB  1 
ATOM   2201  N  N   . LEU A 1 286 ? -23.907 4.666   -5.349  1.00 31.05  ? 286 LEU A N   1 
ATOM   2202  C  CA  . LEU A 1 286 ? -23.902 5.686   -4.318  1.00 29.57  ? 286 LEU A CA  1 
ATOM   2203  C  C   . LEU A 1 286 ? -24.939 6.739   -4.672  1.00 25.48  ? 286 LEU A C   1 
ATOM   2204  O  O   . LEU A 1 286 ? -25.551 6.705   -5.740  1.00 31.67  ? 286 LEU A O   1 
ATOM   2205  C  CB  . LEU A 1 286 ? -22.500 6.281   -4.137  1.00 28.79  ? 286 LEU A CB  1 
ATOM   2206  C  CG  . LEU A 1 286 ? -21.680 6.577   -5.393  1.00 29.64  ? 286 LEU A CG  1 
ATOM   2207  C  CD1 . LEU A 1 286 ? -22.146 7.837   -6.121  1.00 35.73  ? 286 LEU A CD1 1 
ATOM   2208  C  CD2 . LEU A 1 286 ? -20.201 6.639   -5.060  1.00 30.75  ? 286 LEU A CD2 1 
ATOM   2209  N  N   . LEU A 1 287 ? -25.171 7.656   -3.751  1.00 27.01  ? 287 LEU A N   1 
ATOM   2210  C  CA  . LEU A 1 287 ? -26.199 8.667   -3.948  1.00 29.13  ? 287 LEU A CA  1 
ATOM   2211  C  C   . LEU A 1 287 ? -25.629 9.850   -4.742  1.00 25.38  ? 287 LEU A C   1 
ATOM   2212  O  O   . LEU A 1 287 ? -24.756 10.571  -4.251  1.00 19.85  ? 287 LEU A O   1 
ATOM   2213  C  CB  . LEU A 1 287 ? -26.764 9.094   -2.592  1.00 22.09  ? 287 LEU A CB  1 
ATOM   2214  C  CG  . LEU A 1 287 ? -27.344 7.909   -1.799  1.00 23.00  ? 287 LEU A CG  1 
ATOM   2215  C  CD1 . LEU A 1 287 ? -27.817 8.321   -0.434  1.00 21.35  ? 287 LEU A CD1 1 
ATOM   2216  C  CD2 . LEU A 1 287 ? -28.467 7.220   -2.549  1.00 25.47  ? 287 LEU A CD2 1 
ATOM   2217  N  N   . GLU A 1 288 ? -26.158 10.065  -5.951  1.00 25.62  ? 288 GLU A N   1 
ATOM   2218  C  CA  . GLU A 1 288 ? -25.672 11.107  -6.859  1.00 28.34  ? 288 GLU A CA  1 
ATOM   2219  C  C   . GLU A 1 288 ? -26.215 12.486  -6.488  1.00 28.41  ? 288 GLU A C   1 
ATOM   2220  O  O   . GLU A 1 288 ? -27.427 12.670  -6.340  1.00 25.76  ? 288 GLU A O   1 
ATOM   2221  C  CB  . GLU A 1 288 ? -26.054 10.764  -8.300  1.00 27.31  ? 288 GLU A CB  1 
ATOM   2222  C  CG  . GLU A 1 288 ? -25.098 9.785   -8.994  1.00 38.85  ? 288 GLU A CG  1 
ATOM   2223  C  CD  . GLU A 1 288 ? -23.804 10.487  -9.467  1.00 45.53  ? 288 GLU A CD  1 
ATOM   2224  O  OE1 . GLU A 1 288 ? -23.812 11.745  -9.603  1.00 35.43  ? 288 GLU A OE1 1 
ATOM   2225  O  OE2 . GLU A 1 288 ? -22.793 9.778   -9.703  1.00 48.64  ? 288 GLU A OE2 1 
ATOM   2226  N  N   . ASP A 1 289 ? -25.318 13.468  -6.371  1.00 26.97  ? 289 ASP A N   1 
ATOM   2227  C  CA  . ASP A 1 289 ? -25.714 14.816  -5.984  1.00 21.41  ? 289 ASP A CA  1 
ATOM   2228  C  C   . ASP A 1 289 ? -25.310 15.867  -7.022  1.00 25.68  ? 289 ASP A C   1 
ATOM   2229  O  O   . ASP A 1 289 ? -25.239 17.068  -6.704  1.00 22.45  ? 289 ASP A O   1 
ATOM   2230  C  CB  . ASP A 1 289 ? -25.158 15.142  -4.595  1.00 21.36  ? 289 ASP A CB  1 
ATOM   2231  C  CG  . ASP A 1 289 ? -23.650 15.415  -4.588  1.00 26.04  ? 289 ASP A CG  1 
ATOM   2232  O  OD1 . ASP A 1 289 ? -22.947 14.989  -5.534  1.00 26.15  ? 289 ASP A OD1 1 
ATOM   2233  O  OD2 . ASP A 1 289 ? -23.163 16.016  -3.589  1.00 27.49  ? 289 ASP A OD2 1 
ATOM   2234  N  N   . GLU A 1 290 ? -25.047 15.457  -8.266  1.00 24.07  ? 290 GLU A N   1 
ATOM   2235  C  CA  . GLU A 1 290 ? -24.676 16.437  -9.285  1.00 24.24  ? 290 GLU A CA  1 
ATOM   2236  C  C   . GLU A 1 290 ? -25.703 16.507  -10.407 1.00 21.76  ? 290 GLU A C   1 
ATOM   2237  O  O   . GLU A 1 290 ? -25.356 16.776  -11.548 1.00 23.10  ? 290 GLU A O   1 
ATOM   2238  C  CB  . GLU A 1 290 ? -23.261 16.193  -9.823  1.00 21.94  ? 290 GLU A CB  1 
ATOM   2239  C  CG  . GLU A 1 290 ? -22.191 16.564  -8.766  1.00 24.39  ? 290 GLU A CG  1 
ATOM   2240  C  CD  . GLU A 1 290 ? -20.776 16.767  -9.325  1.00 30.83  ? 290 GLU A CD  1 
ATOM   2241  O  OE1 . GLU A 1 290 ? -20.567 16.456  -10.522 1.00 31.70  ? 290 GLU A OE1 1 
ATOM   2242  O  OE2 . GLU A 1 290 ? -19.870 17.211  -8.548  1.00 23.90  ? 290 GLU A OE2 1 
ATOM   2243  N  N   . PHE A 1 291 ? -26.971 16.256  -10.087 1.00 22.02  ? 291 PHE A N   1 
ATOM   2244  C  CA  . PHE A 1 291 ? -28.099 16.622  -10.939 1.00 22.35  ? 291 PHE A CA  1 
ATOM   2245  C  C   . PHE A 1 291 ? -28.970 17.585  -10.139 1.00 21.14  ? 291 PHE A C   1 
ATOM   2246  O  O   . PHE A 1 291 ? -29.503 17.211  -9.087  1.00 16.58  ? 291 PHE A O   1 
ATOM   2247  C  CB  . PHE A 1 291 ? -28.943 15.413  -11.379 1.00 24.89  ? 291 PHE A CB  1 
ATOM   2248  C  CG  . PHE A 1 291 ? -28.237 14.433  -12.301 1.00 22.58  ? 291 PHE A CG  1 
ATOM   2249  C  CD1 . PHE A 1 291 ? -28.117 14.688  -13.656 1.00 25.43  ? 291 PHE A CD1 1 
ATOM   2250  C  CD2 . PHE A 1 291 ? -27.781 13.205  -11.812 1.00 28.19  ? 291 PHE A CD2 1 
ATOM   2251  C  CE1 . PHE A 1 291 ? -27.500 13.770  -14.500 1.00 29.65  ? 291 PHE A CE1 1 
ATOM   2252  C  CE2 . PHE A 1 291 ? -27.167 12.281  -12.648 1.00 21.85  ? 291 PHE A CE2 1 
ATOM   2253  C  CZ  . PHE A 1 291 ? -27.034 12.559  -13.986 1.00 24.68  ? 291 PHE A CZ  1 
ATOM   2254  N  N   . THR A 1 292 ? -29.084 18.826  -10.610 1.00 20.57  ? 292 THR A N   1 
ATOM   2255  C  CA  . THR A 1 292 ? -30.014 19.751  -9.989  1.00 21.40  ? 292 THR A CA  1 
ATOM   2256  C  C   . THR A 1 292 ? -31.442 19.349  -10.333 1.00 20.30  ? 292 THR A C   1 
ATOM   2257  O  O   . THR A 1 292 ? -31.681 18.578  -11.267 1.00 19.69  ? 292 THR A O   1 
ATOM   2258  C  CB  . THR A 1 292 ? -29.765 21.193  -10.446 1.00 22.32  ? 292 THR A CB  1 
ATOM   2259  O  OG1 . THR A 1 292 ? -30.201 21.358  -11.807 1.00 21.77  ? 292 THR A OG1 1 
ATOM   2260  C  CG2 . THR A 1 292 ? -28.290 21.538  -10.329 1.00 20.36  ? 292 THR A CG2 1 
ATOM   2261  N  N   . PRO A 1 293 ? -32.417 19.880  -9.606  1.00 23.60  ? 293 PRO A N   1 
ATOM   2262  C  CA  . PRO A 1 293 ? -33.811 19.647  -10.009 1.00 24.85  ? 293 PRO A CA  1 
ATOM   2263  C  C   . PRO A 1 293 ? -34.109 20.108  -11.425 1.00 24.67  ? 293 PRO A C   1 
ATOM   2264  O  O   . PRO A 1 293 ? -34.918 19.465  -12.111 1.00 25.77  ? 293 PRO A O   1 
ATOM   2265  C  CB  . PRO A 1 293 ? -34.608 20.428  -8.953  1.00 23.27  ? 293 PRO A CB  1 
ATOM   2266  C  CG  . PRO A 1 293 ? -33.716 20.412  -7.750  1.00 20.22  ? 293 PRO A CG  1 
ATOM   2267  C  CD  . PRO A 1 293 ? -32.322 20.519  -8.277  1.00 19.08  ? 293 PRO A CD  1 
ATOM   2268  N  N   . PHE A 1 294 ? -33.455 21.179  -11.892 1.00 20.68  ? 294 PHE A N   1 
ATOM   2269  C  CA  . PHE A 1 294 ? -33.622 21.619  -13.270 1.00 21.70  ? 294 PHE A CA  1 
ATOM   2270  C  C   . PHE A 1 294 ? -33.005 20.638  -14.256 1.00 23.27  ? 294 PHE A C   1 
ATOM   2271  O  O   . PHE A 1 294 ? -33.560 20.439  -15.336 1.00 25.10  ? 294 PHE A O   1 
ATOM   2272  C  CB  . PHE A 1 294 ? -33.030 23.019  -13.459 1.00 31.44  ? 294 PHE A CB  1 
ATOM   2273  C  CG  . PHE A 1 294 ? -32.985 23.487  -14.907 1.00 36.79  ? 294 PHE A CG  1 
ATOM   2274  C  CD1 . PHE A 1 294 ? -31.929 23.119  -15.750 1.00 38.67  ? 294 PHE A CD1 1 
ATOM   2275  C  CD2 . PHE A 1 294 ? -33.984 24.313  -15.416 1.00 40.72  ? 294 PHE A CD2 1 
ATOM   2276  C  CE1 . PHE A 1 294 ? -31.886 23.539  -17.075 1.00 41.01  ? 294 PHE A CE1 1 
ATOM   2277  C  CE2 . PHE A 1 294 ? -33.939 24.753  -16.733 1.00 42.03  ? 294 PHE A CE2 1 
ATOM   2278  C  CZ  . PHE A 1 294 ? -32.890 24.363  -17.565 1.00 40.99  ? 294 PHE A CZ  1 
ATOM   2279  N  N   . ASP A 1 295 ? -31.820 20.085  -13.948 1.00 24.36  ? 295 ASP A N   1 
ATOM   2280  C  CA  . ASP A 1 295 ? -31.201 19.092  -14.832 1.00 20.69  ? 295 ASP A CA  1 
ATOM   2281  C  C   . ASP A 1 295 ? -32.142 17.930  -15.079 1.00 25.69  ? 295 ASP A C   1 
ATOM   2282  O  O   . ASP A 1 295 ? -32.297 17.469  -16.220 1.00 24.58  ? 295 ASP A O   1 
ATOM   2283  C  CB  . ASP A 1 295 ? -29.902 18.547  -14.241 1.00 21.24  ? 295 ASP A CB  1 
ATOM   2284  C  CG  . ASP A 1 295 ? -28.827 19.595  -14.090 1.00 26.15  ? 295 ASP A CG  1 
ATOM   2285  O  OD1 . ASP A 1 295 ? -28.991 20.693  -14.653 1.00 28.14  ? 295 ASP A OD1 1 
ATOM   2286  O  OD2 . ASP A 1 295 ? -27.818 19.326  -13.388 1.00 20.81  ? 295 ASP A OD2 1 
ATOM   2287  N  N   . VAL A 1 296 ? -32.766 17.433  -14.000 1.00 26.63  ? 296 VAL A N   1 
ATOM   2288  C  CA  . VAL A 1 296 ? -33.649 16.270  -14.082 1.00 25.35  ? 296 VAL A CA  1 
ATOM   2289  C  C   . VAL A 1 296 ? -34.822 16.554  -15.010 1.00 27.45  ? 296 VAL A C   1 
ATOM   2290  O  O   . VAL A 1 296 ? -35.051 15.829  -15.989 1.00 27.69  ? 296 VAL A O   1 
ATOM   2291  C  CB  . VAL A 1 296 ? -34.140 15.870  -12.679 1.00 21.03  ? 296 VAL A CB  1 
ATOM   2292  C  CG1 . VAL A 1 296 ? -35.132 14.750  -12.795 1.00 22.21  ? 296 VAL A CG1 1 
ATOM   2293  C  CG2 . VAL A 1 296 ? -32.966 15.477  -11.794 1.00 22.84  ? 296 VAL A CG2 1 
ATOM   2294  N  N   . VAL A 1 297 ? -35.574 17.621  -14.717 1.00 23.01  ? 297 VAL A N   1 
ATOM   2295  C  CA  . VAL A 1 297 ? -36.721 17.997  -15.550 1.00 29.83  ? 297 VAL A CA  1 
ATOM   2296  C  C   . VAL A 1 297 ? -36.290 18.154  -17.005 1.00 29.38  ? 297 VAL A C   1 
ATOM   2297  O  O   . VAL A 1 297 ? -36.887 17.566  -17.916 1.00 32.07  ? 297 VAL A O   1 
ATOM   2298  C  CB  . VAL A 1 297 ? -37.374 19.290  -15.011 1.00 28.08  ? 297 VAL A CB  1 
ATOM   2299  C  CG1 . VAL A 1 297 ? -38.391 19.865  -15.994 1.00 25.53  ? 297 VAL A CG1 1 
ATOM   2300  C  CG2 . VAL A 1 297 ? -38.037 19.027  -13.680 1.00 23.73  ? 297 VAL A CG2 1 
ATOM   2301  N  N   . ARG A 1 298 ? -35.206 18.899  -17.226 1.00 25.70  ? 298 ARG A N   1 
ATOM   2302  C  CA  . ARG A 1 298 ? -34.706 19.164  -18.574 1.00 30.33  ? 298 ARG A CA  1 
ATOM   2303  C  C   . ARG A 1 298 ? -34.397 17.871  -19.319 1.00 34.64  ? 298 ARG A C   1 
ATOM   2304  O  O   . ARG A 1 298 ? -34.724 17.725  -20.507 1.00 35.92  ? 298 ARG A O   1 
ATOM   2305  C  CB  . ARG A 1 298 ? -33.463 20.057  -18.502 1.00 34.39  ? 298 ARG A CB  1 
ATOM   2306  C  CG  . ARG A 1 298 ? -32.799 20.361  -19.841 1.00 36.05  ? 298 ARG A CG  1 
ATOM   2307  C  CD  . ARG A 1 298 ? -31.569 21.288  -19.684 1.00 42.04  ? 298 ARG A CD  1 
ATOM   2308  N  NE  . ARG A 1 298 ? -30.440 20.600  -19.059 1.00 49.73  ? 298 ARG A NE  1 
ATOM   2309  C  CZ  . ARG A 1 298 ? -29.451 20.019  -19.732 1.00 53.59  ? 298 ARG A CZ  1 
ATOM   2310  N  NH1 . ARG A 1 298 ? -29.408 20.047  -21.056 1.00 43.31  ? 298 ARG A NH1 1 
ATOM   2311  N  NH2 . ARG A 1 298 ? -28.499 19.361  -19.062 1.00 43.82  ? 298 ARG A NH2 1 
ATOM   2312  N  N   . GLN A 1 299 ? -33.685 16.951  -18.669 1.00 32.78  ? 299 GLN A N   1 
ATOM   2313  C  CA  . GLN A 1 299 ? -33.329 15.730  -19.372 1.00 29.71  ? 299 GLN A CA  1 
ATOM   2314  C  C   . GLN A 1 299 ? -34.547 14.862  -19.602 1.00 32.46  ? 299 GLN A C   1 
ATOM   2315  O  O   . GLN A 1 299 ? -34.673 14.235  -20.657 1.00 31.06  ? 299 GLN A O   1 
ATOM   2316  C  CB  . GLN A 1 299 ? -32.288 14.936  -18.608 1.00 26.02  ? 299 GLN A CB  1 
ATOM   2317  C  CG  . GLN A 1 299 ? -31.850 13.724  -19.395 1.00 23.53  ? 299 GLN A CG  1 
ATOM   2318  C  CD  . GLN A 1 299 ? -30.778 12.946  -18.706 1.00 22.99  ? 299 GLN A CD  1 
ATOM   2319  O  OE1 . GLN A 1 299 ? -30.574 11.783  -19.012 1.00 25.72  ? 299 GLN A OE1 1 
ATOM   2320  N  NE2 . GLN A 1 299 ? -30.072 13.580  -17.770 1.00 22.41  ? 299 GLN A NE2 1 
ATOM   2321  N  N   . CYS A 1 300 ? -35.468 14.828  -18.640 1.00 34.21  ? 300 CYS A N   1 
ATOM   2322  C  CA  . CYS A 1 300 ? -36.611 13.941  -18.773 1.00 30.35  ? 300 CYS A CA  1 
ATOM   2323  C  C   . CYS A 1 300 ? -37.694 14.509  -19.679 1.00 36.03  ? 300 CYS A C   1 
ATOM   2324  O  O   . CYS A 1 300 ? -38.591 13.760  -20.066 1.00 40.98  ? 300 CYS A O   1 
ATOM   2325  C  CB  . CYS A 1 300 ? -37.207 13.624  -17.402 1.00 29.04  ? 300 CYS A CB  1 
ATOM   2326  S  SG  . CYS A 1 300 ? -36.154 12.592  -16.348 1.00 35.21  ? 300 CYS A SG  1 
ATOM   2327  N  N   . SER A 1 301 ? -37.608 15.779  -20.079 1.00 30.80  ? 301 SER A N   1 
ATOM   2328  C  CA  . SER A 1 301 ? -38.619 16.358  -20.957 1.00 32.31  ? 301 SER A CA  1 
ATOM   2329  C  C   . SER A 1 301 ? -38.137 16.566  -22.387 1.00 36.89  ? 301 SER A C   1 
ATOM   2330  O  O   . SER A 1 301 ? -38.969 16.747  -23.282 1.00 32.54  ? 301 SER A O   1 
ATOM   2331  C  CB  . SER A 1 301 ? -39.106 17.710  -20.404 1.00 37.05  ? 301 SER A CB  1 
ATOM   2332  O  OG  . SER A 1 301 ? -38.261 18.780  -20.824 1.00 31.22  ? 301 SER A OG  1 
ATOM   2333  N  N   . GLY A 1 302 ? -36.827 16.571  -22.624 1.00 40.71  ? 302 GLY A N   1 
ATOM   2334  C  CA  . GLY A 1 302 ? -36.319 16.628  -23.976 1.00 32.18  ? 302 GLY A CA  1 
ATOM   2335  C  C   . GLY A 1 302 ? -36.063 18.023  -24.474 1.00 30.81  ? 302 GLY A C   1 
ATOM   2336  O  O   . GLY A 1 302 ? -36.237 18.279  -25.666 1.00 35.66  ? 302 GLY A O   1 
ATOM   2337  N  N   . VAL A 1 303 ? -35.702 18.951  -23.592 1.00 35.55  ? 303 VAL A N   1 
ATOM   2338  C  CA  . VAL A 1 303 ? -35.488 20.334  -24.009 1.00 37.25  ? 303 VAL A CA  1 
ATOM   2339  C  C   . VAL A 1 303 ? -34.269 20.425  -24.919 1.00 34.02  ? 303 VAL A C   1 
ATOM   2340  O  O   . VAL A 1 303 ? -33.210 19.846  -24.638 1.00 28.97  ? 303 VAL A O   1 
ATOM   2341  C  CB  . VAL A 1 303 ? -35.355 21.241  -22.774 1.00 36.62  ? 303 VAL A CB  1 
ATOM   2342  C  CG1 . VAL A 1 303 ? -34.798 22.628  -23.145 1.00 34.15  ? 303 VAL A CG1 1 
ATOM   2343  C  CG2 . VAL A 1 303 ? -36.709 21.354  -22.083 1.00 29.01  ? 303 VAL A CG2 1 
ATOM   2344  N  N   . THR A 1 304 ? -34.398 21.192  -26.000 1.00 36.56  ? 304 THR A N   1 
ATOM   2345  C  CA  . THR A 1 304 ? -33.333 21.303  -26.983 1.00 36.20  ? 304 THR A CA  1 
ATOM   2346  C  C   . THR A 1 304 ? -32.773 22.724  -26.995 1.00 37.75  ? 304 THR A C   1 
ATOM   2347  O  O   . THR A 1 304 ? -33.308 23.642  -26.363 1.00 37.23  ? 304 THR A O   1 
ATOM   2348  C  CB  . THR A 1 304 ? -33.845 20.908  -28.377 1.00 36.66  ? 304 THR A CB  1 
ATOM   2349  O  OG1 . THR A 1 304 ? -34.864 21.819  -28.813 1.00 36.28  ? 304 THR A OG1 1 
ATOM   2350  C  CG2 . THR A 1 304 ? -34.463 19.526  -28.310 1.00 29.06  ? 304 THR A CG2 1 
ATOM   2351  N  N   . PHE A 1 305 ? -31.681 22.895  -27.742 1.00 39.15  ? 305 PHE A N   1 
ATOM   2352  C  CA  . PHE A 1 305 ? -30.978 24.182  -27.845 1.00 47.09  ? 305 PHE A CA  1 
ATOM   2353  C  C   . PHE A 1 305 ? -30.573 24.481  -29.291 1.00 41.02  ? 305 PHE A C   1 
ATOM   2354  O  O   . PHE A 1 305 ? -30.629 25.635  -29.732 1.00 55.84  ? 305 PHE A O   1 
ATOM   2355  C  CB  . PHE A 1 305 ? -29.731 24.206  -26.931 1.00 38.30  ? 305 PHE A CB  1 
ATOM   2356  C  CG  . PHE A 1 305 ? -30.005 23.781  -25.528 1.00 30.77  ? 305 PHE A CG  1 
ATOM   2357  C  CD1 . PHE A 1 305 ? -30.574 24.670  -24.623 1.00 28.77  ? 305 PHE A CD1 1 
ATOM   2358  C  CD2 . PHE A 1 305 ? -29.750 22.478  -25.126 1.00 32.98  ? 305 PHE A CD2 1 
ATOM   2359  C  CE1 . PHE A 1 305 ? -30.851 24.286  -23.320 1.00 33.25  ? 305 PHE A CE1 1 
ATOM   2360  C  CE2 . PHE A 1 305 ? -30.038 22.062  -23.813 1.00 36.53  ? 305 PHE A CE2 1 
ATOM   2361  C  CZ  . PHE A 1 305 ? -30.594 22.969  -22.909 1.00 36.12  ? 305 PHE A CZ  1 
ATOM   2362  N  N   . SER B 1 1   ? -5.044  16.365  -12.869 1.00 35.92  ? 1   SER B N   1 
ATOM   2363  C  CA  . SER B 1 1   ? -5.593  15.042  -12.584 1.00 34.01  ? 1   SER B CA  1 
ATOM   2364  C  C   . SER B 1 1   ? -7.112  15.067  -12.645 1.00 30.28  ? 1   SER B C   1 
ATOM   2365  O  O   . SER B 1 1   ? -7.704  15.980  -13.215 1.00 28.12  ? 1   SER B O   1 
ATOM   2366  C  CB  . SER B 1 1   ? -5.151  14.551  -11.204 1.00 33.58  ? 1   SER B CB  1 
ATOM   2367  O  OG  . SER B 1 1   ? -5.560  15.473  -10.199 1.00 44.17  ? 1   SER B OG  1 
ATOM   2368  N  N   . GLY B 1 2   ? -7.733  14.079  -12.015 1.00 29.41  ? 2   GLY B N   1 
ATOM   2369  C  CA  . GLY B 1 2   ? -9.165  13.881  -12.138 1.00 25.12  ? 2   GLY B CA  1 
ATOM   2370  C  C   . GLY B 1 2   ? -9.490  12.956  -13.289 1.00 26.14  ? 2   GLY B C   1 
ATOM   2371  O  O   . GLY B 1 2   ? -8.713  12.790  -14.227 1.00 26.30  ? 2   GLY B O   1 
ATOM   2372  N  N   . PHE B 1 3   ? -10.646 12.294  -13.192 1.00 29.95  ? 3   PHE B N   1 
ATOM   2373  C  CA  . PHE B 1 3   ? -11.059 11.369  -14.246 1.00 24.09  ? 3   PHE B CA  1 
ATOM   2374  C  C   . PHE B 1 3   ? -12.577 11.396  -14.316 1.00 26.09  ? 3   PHE B C   1 
ATOM   2375  O  O   . PHE B 1 3   ? -13.239 10.960  -13.376 1.00 30.01  ? 3   PHE B O   1 
ATOM   2376  C  CB  . PHE B 1 3   ? -10.547 9.961   -13.973 1.00 23.24  ? 3   PHE B CB  1 
ATOM   2377  C  CG  . PHE B 1 3   ? -10.436 9.101   -15.215 1.00 26.74  ? 3   PHE B CG  1 
ATOM   2378  C  CD1 . PHE B 1 3   ? -9.324  9.222   -16.055 1.00 22.29  ? 3   PHE B CD1 1 
ATOM   2379  C  CD2 . PHE B 1 3   ? -11.436 8.200   -15.548 1.00 19.55  ? 3   PHE B CD2 1 
ATOM   2380  C  CE1 . PHE B 1 3   ? -9.205  8.457   -17.197 1.00 25.12  ? 3   PHE B CE1 1 
ATOM   2381  C  CE2 . PHE B 1 3   ? -11.329 7.427   -16.687 1.00 23.36  ? 3   PHE B CE2 1 
ATOM   2382  C  CZ  . PHE B 1 3   ? -10.208 7.556   -17.520 1.00 26.57  ? 3   PHE B CZ  1 
ATOM   2383  N  N   . ARG B 1 4   ? -13.123 11.885  -15.427 1.00 26.46  ? 4   ARG B N   1 
ATOM   2384  C  CA  . ARG B 1 4   ? -14.556 12.059  -15.601 1.00 23.97  ? 4   ARG B CA  1 
ATOM   2385  C  C   . ARG B 1 4   ? -15.025 11.280  -16.824 1.00 27.60  ? 4   ARG B C   1 
ATOM   2386  O  O   . ARG B 1 4   ? -14.261 11.054  -17.770 1.00 23.01  ? 4   ARG B O   1 
ATOM   2387  C  CB  . ARG B 1 4   ? -14.915 13.546  -15.775 1.00 25.29  ? 4   ARG B CB  1 
ATOM   2388  C  CG  . ARG B 1 4   ? -15.069 14.334  -14.476 1.00 26.37  ? 4   ARG B CG  1 
ATOM   2389  C  CD  . ARG B 1 4   ? -16.503 14.322  -13.987 1.00 27.92  ? 4   ARG B CD  1 
ATOM   2390  N  NE  . ARG B 1 4   ? -16.718 15.268  -12.900 1.00 33.79  ? 4   ARG B NE  1 
ATOM   2391  C  CZ  . ARG B 1 4   ? -17.792 15.268  -12.116 1.00 41.51  ? 4   ARG B CZ  1 
ATOM   2392  N  NH1 . ARG B 1 4   ? -18.784 14.410  -12.303 1.00 44.85  ? 4   ARG B NH1 1 
ATOM   2393  N  NH2 . ARG B 1 4   ? -17.877 16.152  -11.121 1.00 27.59  ? 4   ARG B NH2 1 
ATOM   2394  N  N   . LYS B 1 5   ? -16.298 10.889  -16.811 1.00 27.59  ? 5   LYS B N   1 
ATOM   2395  C  CA  . LYS B 1 5   ? -16.921 10.376  -18.023 1.00 29.04  ? 5   LYS B CA  1 
ATOM   2396  C  C   . LYS B 1 5   ? -17.026 11.532  -19.019 1.00 27.96  ? 5   LYS B C   1 
ATOM   2397  O  O   . LYS B 1 5   ? -17.816 12.468  -18.842 1.00 32.29  ? 5   LYS B O   1 
ATOM   2398  C  CB  . LYS B 1 5   ? -18.282 9.763   -17.714 1.00 27.79  ? 5   LYS B CB  1 
ATOM   2399  C  CG  . LYS B 1 5   ? -18.883 9.025   -18.888 1.00 32.75  ? 5   LYS B CG  1 
ATOM   2400  C  CD  . LYS B 1 5   ? -18.038 7.823   -19.315 1.00 34.75  ? 5   LYS B CD  1 
ATOM   2401  C  CE  . LYS B 1 5   ? -18.250 6.599   -18.433 1.00 33.05  ? 5   LYS B CE  1 
ATOM   2402  N  NZ  . LYS B 1 5   ? -19.597 6.016   -18.641 1.00 42.83  ? 5   LYS B NZ  1 
ATOM   2403  N  N   . MET B 1 6   ? -16.203 11.480  -20.052 1.00 24.75  ? 6   MET B N   1 
ATOM   2404  C  CA  . MET B 1 6   ? -15.947 12.626  -20.907 1.00 30.81  ? 6   MET B CA  1 
ATOM   2405  C  C   . MET B 1 6   ? -16.450 12.294  -22.302 1.00 27.87  ? 6   MET B C   1 
ATOM   2406  O  O   . MET B 1 6   ? -16.089 11.251  -22.858 1.00 27.16  ? 6   MET B O   1 
ATOM   2407  C  CB  . MET B 1 6   ? -14.450 12.934  -20.901 1.00 21.74  ? 6   MET B CB  1 
ATOM   2408  C  CG  . MET B 1 6   ? -14.092 14.338  -21.241 1.00 34.76  ? 6   MET B CG  1 
ATOM   2409  S  SD  . MET B 1 6   ? -12.311 14.567  -21.235 1.00 39.81  ? 6   MET B SD  1 
ATOM   2410  C  CE  . MET B 1 6   ? -12.064 15.341  -19.637 1.00 27.91  ? 6   MET B CE  1 
ATOM   2411  N  N   . ALA B 1 7   ? -17.278 13.176  -22.864 1.00 24.97  ? 7   ALA B N   1 
ATOM   2412  C  CA  . ALA B 1 7   ? -17.803 13.014  -24.213 1.00 24.06  ? 7   ALA B CA  1 
ATOM   2413  C  C   . ALA B 1 7   ? -16.937 13.784  -25.193 1.00 23.54  ? 7   ALA B C   1 
ATOM   2414  O  O   . ALA B 1 7   ? -16.215 14.700  -24.806 1.00 26.05  ? 7   ALA B O   1 
ATOM   2415  C  CB  . ALA B 1 7   ? -19.246 13.509  -24.295 1.00 18.85  ? 7   ALA B CB  1 
ATOM   2416  N  N   . PHE B 1 8   ? -16.938 13.358  -26.449 1.00 20.74  ? 8   PHE B N   1 
ATOM   2417  C  CA  . PHE B 1 8   ? -16.306 14.184  -27.467 1.00 25.69  ? 8   PHE B CA  1 
ATOM   2418  C  C   . PHE B 1 8   ? -17.080 15.486  -27.648 1.00 25.70  ? 8   PHE B C   1 
ATOM   2419  O  O   . PHE B 1 8   ? -18.314 15.499  -27.580 1.00 25.69  ? 8   PHE B O   1 
ATOM   2420  C  CB  . PHE B 1 8   ? -16.200 13.452  -28.805 1.00 23.69  ? 8   PHE B CB  1 
ATOM   2421  C  CG  . PHE B 1 8   ? -15.125 12.406  -28.840 1.00 24.35  ? 8   PHE B CG  1 
ATOM   2422  C  CD1 . PHE B 1 8   ? -13.795 12.767  -28.982 1.00 29.31  ? 8   PHE B CD1 1 
ATOM   2423  C  CD2 . PHE B 1 8   ? -15.435 11.056  -28.744 1.00 30.97  ? 8   PHE B CD2 1 
ATOM   2424  C  CE1 . PHE B 1 8   ? -12.788 11.785  -29.013 1.00 37.37  ? 8   PHE B CE1 1 
ATOM   2425  C  CE2 . PHE B 1 8   ? -14.434 10.074  -28.790 1.00 25.94  ? 8   PHE B CE2 1 
ATOM   2426  C  CZ  . PHE B 1 8   ? -13.113 10.443  -28.915 1.00 27.78  ? 8   PHE B CZ  1 
ATOM   2427  N  N   . PRO B 1 9   ? -16.388 16.583  -27.935 1.00 26.55  ? 9   PRO B N   1 
ATOM   2428  C  CA  . PRO B 1 9   ? -17.097 17.820  -28.307 1.00 25.86  ? 9   PRO B CA  1 
ATOM   2429  C  C   . PRO B 1 9   ? -17.998 17.596  -29.517 1.00 25.09  ? 9   PRO B C   1 
ATOM   2430  O  O   . PRO B 1 9   ? -17.629 16.907  -30.474 1.00 24.10  ? 9   PRO B O   1 
ATOM   2431  C  CB  . PRO B 1 9   ? -15.963 18.815  -28.596 1.00 23.37  ? 9   PRO B CB  1 
ATOM   2432  C  CG  . PRO B 1 9   ? -14.750 17.982  -28.853 1.00 27.64  ? 9   PRO B CG  1 
ATOM   2433  C  CD  . PRO B 1 9   ? -14.922 16.716  -28.037 1.00 28.24  ? 9   PRO B CD  1 
ATOM   2434  N  N   . SER B 1 10  ? -19.204 18.177  -29.460 1.00 19.87  ? 10  SER B N   1 
ATOM   2435  C  CA  . SER B 1 10  ? -20.273 17.793  -30.375 1.00 20.62  ? 10  SER B CA  1 
ATOM   2436  C  C   . SER B 1 10  ? -20.482 18.779  -31.509 1.00 21.74  ? 10  SER B C   1 
ATOM   2437  O  O   . SER B 1 10  ? -21.377 18.571  -32.348 1.00 19.97  ? 10  SER B O   1 
ATOM   2438  C  CB  . SER B 1 10  ? -21.586 17.632  -29.609 1.00 22.96  ? 10  SER B CB  1 
ATOM   2439  O  OG  . SER B 1 10  ? -21.987 18.882  -29.057 1.00 24.69  ? 10  SER B OG  1 
ATOM   2440  N  N   . GLY B 1 11  ? -19.668 19.832  -31.566 1.00 24.79  ? 11  GLY B N   1 
ATOM   2441  C  CA  . GLY B 1 11  ? -19.894 20.871  -32.555 1.00 19.58  ? 11  GLY B CA  1 
ATOM   2442  C  C   . GLY B 1 11  ? -19.909 20.329  -33.968 1.00 18.23  ? 11  GLY B C   1 
ATOM   2443  O  O   . GLY B 1 11  ? -20.860 20.567  -34.719 1.00 23.35  ? 11  GLY B O   1 
ATOM   2444  N  N   . LYS B 1 12  ? -18.875 19.564  -34.344 1.00 17.42  ? 12  LYS B N   1 
ATOM   2445  C  CA  . LYS B 1 12  ? -18.818 19.047  -35.711 1.00 21.15  ? 12  LYS B CA  1 
ATOM   2446  C  C   . LYS B 1 12  ? -20.080 18.287  -36.088 1.00 21.70  ? 12  LYS B C   1 
ATOM   2447  O  O   . LYS B 1 12  ? -20.437 18.235  -37.264 1.00 24.15  ? 12  LYS B O   1 
ATOM   2448  C  CB  . LYS B 1 12  ? -17.603 18.140  -35.918 1.00 23.80  ? 12  LYS B CB  1 
ATOM   2449  C  CG  . LYS B 1 12  ? -16.262 18.809  -35.909 1.00 24.38  ? 12  LYS B CG  1 
ATOM   2450  C  CD  . LYS B 1 12  ? -15.196 17.804  -36.237 1.00 27.80  ? 12  LYS B CD  1 
ATOM   2451  C  CE  . LYS B 1 12  ? -13.816 18.394  -36.088 1.00 36.79  ? 12  LYS B CE  1 
ATOM   2452  N  NZ  . LYS B 1 12  ? -13.651 19.481  -37.095 1.00 39.08  ? 12  LYS B NZ  1 
ATOM   2453  N  N   . VAL B 1 13  ? -20.745 17.669  -35.115 1.00 20.41  ? 13  VAL B N   1 
ATOM   2454  C  CA  . VAL B 1 13  ? -21.939 16.880  -35.386 1.00 20.75  ? 13  VAL B CA  1 
ATOM   2455  C  C   . VAL B 1 13  ? -23.217 17.715  -35.356 1.00 18.07  ? 13  VAL B C   1 
ATOM   2456  O  O   . VAL B 1 13  ? -24.160 17.406  -36.085 1.00 18.92  ? 13  VAL B O   1 
ATOM   2457  C  CB  . VAL B 1 13  ? -22.007 15.712  -34.382 1.00 19.30  ? 13  VAL B CB  1 
ATOM   2458  C  CG1 . VAL B 1 13  ? -23.210 14.817  -34.643 1.00 19.29  ? 13  VAL B CG1 1 
ATOM   2459  C  CG2 . VAL B 1 13  ? -20.737 14.916  -34.453 1.00 22.40  ? 13  VAL B CG2 1 
ATOM   2460  N  N   . GLU B 1 14  ? -23.289 18.732  -34.487 1.00 19.16  ? 14  GLU B N   1 
ATOM   2461  C  CA  . GLU B 1 14  ? -24.480 19.585  -34.414 1.00 15.85  ? 14  GLU B CA  1 
ATOM   2462  C  C   . GLU B 1 14  ? -24.789 20.208  -35.768 1.00 22.08  ? 14  GLU B C   1 
ATOM   2463  O  O   . GLU B 1 14  ? -25.961 20.335  -36.152 1.00 23.66  ? 14  GLU B O   1 
ATOM   2464  C  CB  . GLU B 1 14  ? -24.295 20.688  -33.361 1.00 18.33  ? 14  GLU B CB  1 
ATOM   2465  C  CG  . GLU B 1 14  ? -24.052 20.174  -31.943 1.00 19.17  ? 14  GLU B CG  1 
ATOM   2466  C  CD  . GLU B 1 14  ? -23.670 21.263  -30.934 1.00 20.83  ? 14  GLU B CD  1 
ATOM   2467  O  OE1 . GLU B 1 14  ? -24.400 22.254  -30.791 1.00 24.76  ? 14  GLU B OE1 1 
ATOM   2468  O  OE2 . GLU B 1 14  ? -22.607 21.164  -30.301 1.00 22.42  ? 14  GLU B OE2 1 
ATOM   2469  N  N   . GLY B 1 15  ? -23.744 20.642  -36.493 1.00 22.27  ? 15  GLY B N   1 
ATOM   2470  C  CA  . GLY B 1 15  ? -23.894 21.243  -37.813 1.00 19.73  ? 15  GLY B CA  1 
ATOM   2471  C  C   . GLY B 1 15  ? -24.425 20.292  -38.862 1.00 20.84  ? 15  GLY B C   1 
ATOM   2472  O  O   . GLY B 1 15  ? -24.719 20.730  -39.986 1.00 12.84  ? 15  GLY B O   1 
ATOM   2473  N  N   . CYS B 1 16  ? -24.583 19.009  -38.509 1.00 16.28  ? 16  CYS B N   1 
ATOM   2474  C  CA  . CYS B 1 16  ? -25.121 18.004  -39.425 1.00 20.05  ? 16  CYS B CA  1 
ATOM   2475  C  C   . CYS B 1 16  ? -26.547 17.567  -39.112 1.00 16.15  ? 16  CYS B C   1 
ATOM   2476  O  O   . CYS B 1 16  ? -27.100 16.776  -39.874 1.00 20.56  ? 16  CYS B O   1 
ATOM   2477  C  CB  . CYS B 1 16  ? -24.225 16.766  -39.441 1.00 18.10  ? 16  CYS B CB  1 
ATOM   2478  S  SG  . CYS B 1 16  ? -22.540 17.129  -39.938 1.00 21.96  ? 16  CYS B SG  1 
ATOM   2479  N  N   . MET B 1 17  ? -27.164 18.038  -38.029 1.00 17.13  ? 17  MET B N   1 
ATOM   2480  C  CA  . MET B 1 17  ? -28.480 17.532  -37.635 1.00 16.81  ? 17  MET B CA  1 
ATOM   2481  C  C   . MET B 1 17  ? -29.615 18.290  -38.322 1.00 21.94  ? 17  MET B C   1 
ATOM   2482  O  O   . MET B 1 17  ? -29.667 19.524  -38.292 1.00 24.75  ? 17  MET B O   1 
ATOM   2483  C  CB  . MET B 1 17  ? -28.674 17.606  -36.117 1.00 18.46  ? 17  MET B CB  1 
ATOM   2484  C  CG  . MET B 1 17  ? -27.704 16.781  -35.284 1.00 21.96  ? 17  MET B CG  1 
ATOM   2485  S  SD  . MET B 1 17  ? -27.603 15.079  -35.867 1.00 25.22  ? 17  MET B SD  1 
ATOM   2486  C  CE  . MET B 1 17  ? -29.329 14.593  -35.777 1.00 21.91  ? 17  MET B CE  1 
ATOM   2487  N  N   . VAL B 1 18  ? -30.556 17.552  -38.894 1.00 19.34  ? 18  VAL B N   1 
ATOM   2488  C  CA  . VAL B 1 18  ? -31.740 18.137  -39.490 1.00 19.29  ? 18  VAL B CA  1 
ATOM   2489  C  C   . VAL B 1 18  ? -32.953 17.408  -38.940 1.00 20.47  ? 18  VAL B C   1 
ATOM   2490  O  O   . VAL B 1 18  ? -32.841 16.446  -38.173 1.00 21.84  ? 18  VAL B O   1 
ATOM   2491  C  CB  . VAL B 1 18  ? -31.732 18.095  -41.036 1.00 21.06  ? 18  VAL B CB  1 
ATOM   2492  C  CG1 . VAL B 1 18  ? -30.583 18.904  -41.619 1.00 21.69  ? 18  VAL B CG1 1 
ATOM   2493  C  CG2 . VAL B 1 18  ? -31.694 16.662  -41.535 1.00 17.24  ? 18  VAL B CG2 1 
ATOM   2494  N  N   . GLN B 1 19  ? -34.118 17.894  -39.335 1.00 20.06  ? 19  GLN B N   1 
ATOM   2495  C  CA  . GLN B 1 19  ? -35.409 17.358  -38.942 1.00 22.29  ? 19  GLN B CA  1 
ATOM   2496  C  C   . GLN B 1 19  ? -36.070 16.751  -40.176 1.00 26.90  ? 19  GLN B C   1 
ATOM   2497  O  O   . GLN B 1 19  ? -36.132 17.386  -41.234 1.00 29.25  ? 19  GLN B O   1 
ATOM   2498  C  CB  . GLN B 1 19  ? -36.256 18.475  -38.341 1.00 25.73  ? 19  GLN B CB  1 
ATOM   2499  C  CG  . GLN B 1 19  ? -37.708 18.182  -38.154 1.00 28.33  ? 19  GLN B CG  1 
ATOM   2500  C  CD  . GLN B 1 19  ? -38.351 19.233  -37.265 1.00 35.73  ? 19  GLN B CD  1 
ATOM   2501  O  OE1 . GLN B 1 19  ? -39.228 18.924  -36.457 1.00 31.81  ? 19  GLN B OE1 1 
ATOM   2502  N  NE2 . GLN B 1 19  ? -37.892 20.490  -37.392 1.00 36.90  ? 19  GLN B NE2 1 
ATOM   2503  N  N   . VAL B 1 20  ? -36.508 15.505  -40.073 1.00 24.15  ? 20  VAL B N   1 
ATOM   2504  C  CA  . VAL B 1 20  ? -37.128 14.822  -41.196 1.00 23.02  ? 20  VAL B CA  1 
ATOM   2505  C  C   . VAL B 1 20  ? -38.563 14.502  -40.812 1.00 28.52  ? 20  VAL B C   1 
ATOM   2506  O  O   . VAL B 1 20  ? -38.820 13.885  -39.766 1.00 26.49  ? 20  VAL B O   1 
ATOM   2507  C  CB  . VAL B 1 20  ? -36.346 13.555  -41.597 1.00 21.57  ? 20  VAL B CB  1 
ATOM   2508  C  CG1 . VAL B 1 20  ? -36.986 12.880  -42.797 1.00 20.22  ? 20  VAL B CG1 1 
ATOM   2509  C  CG2 . VAL B 1 20  ? -34.885 13.910  -41.895 1.00 21.67  ? 20  VAL B CG2 1 
ATOM   2510  N  N   . THR B 1 21  ? -39.492 14.920  -41.657 1.00 27.25  ? 21  THR B N   1 
ATOM   2511  C  CA  . THR B 1 21  ? -40.907 14.689  -41.443 1.00 27.15  ? 21  THR B CA  1 
ATOM   2512  C  C   . THR B 1 21  ? -41.459 13.917  -42.633 1.00 28.13  ? 21  THR B C   1 
ATOM   2513  O  O   . THR B 1 21  ? -41.080 14.171  -43.777 1.00 28.14  ? 21  THR B O   1 
ATOM   2514  C  CB  . THR B 1 21  ? -41.644 16.021  -41.280 1.00 30.31  ? 21  THR B CB  1 
ATOM   2515  O  OG1 . THR B 1 21  ? -41.089 16.740  -40.169 1.00 33.30  ? 21  THR B OG1 1 
ATOM   2516  C  CG2 . THR B 1 21  ? -43.124 15.794  -41.050 1.00 27.22  ? 21  THR B CG2 1 
ATOM   2517  N  N   . CYS B 1 22  ? -42.343 12.967  -42.362 1.00 28.64  ? 22  CYS B N   1 
ATOM   2518  C  CA  . CYS B 1 22  ? -43.040 12.244  -43.425 1.00 33.82  ? 22  CYS B CA  1 
ATOM   2519  C  C   . CYS B 1 22  ? -44.457 11.992  -42.928 1.00 31.17  ? 22  CYS B C   1 
ATOM   2520  O  O   . CYS B 1 22  ? -44.684 11.061  -42.153 1.00 34.26  ? 22  CYS B O   1 
ATOM   2521  C  CB  . CYS B 1 22  ? -42.341 10.942  -43.790 1.00 29.89  ? 22  CYS B CB  1 
ATOM   2522  S  SG  . CYS B 1 22  ? -43.002 10.183  -45.276 1.00 40.93  ? 22  CYS B SG  1 
ATOM   2523  N  N   . GLY B 1 23  ? -45.404 12.804  -43.399 1.00 26.43  ? 23  GLY B N   1 
ATOM   2524  C  CA  . GLY B 1 23  ? -46.745 12.749  -42.870 1.00 28.79  ? 23  GLY B CA  1 
ATOM   2525  C  C   . GLY B 1 23  ? -46.763 13.296  -41.462 1.00 33.16  ? 23  GLY B C   1 
ATOM   2526  O  O   . GLY B 1 23  ? -46.370 14.443  -41.251 1.00 28.53  ? 23  GLY B O   1 
ATOM   2527  N  N   . THR B 1 24  ? -47.191 12.494  -40.478 1.00 36.02  ? 24  THR B N   1 
ATOM   2528  C  CA  . THR B 1 24  ? -47.233 12.959  -39.095 1.00 35.82  ? 24  THR B CA  1 
ATOM   2529  C  C   . THR B 1 24  ? -46.065 12.466  -38.240 1.00 37.25  ? 24  THR B C   1 
ATOM   2530  O  O   . THR B 1 24  ? -46.026 12.761  -37.041 1.00 34.81  ? 24  THR B O   1 
ATOM   2531  C  CB  . THR B 1 24  ? -48.564 12.574  -38.449 1.00 40.74  ? 24  THR B CB  1 
ATOM   2532  O  OG1 . THR B 1 24  ? -48.841 11.191  -38.701 1.00 46.72  ? 24  THR B OG1 1 
ATOM   2533  C  CG2 . THR B 1 24  ? -49.682 13.433  -39.017 1.00 35.59  ? 24  THR B CG2 1 
ATOM   2534  N  N   . THR B 1 25  ? -45.085 11.786  -38.828 1.00 32.19  ? 25  THR B N   1 
ATOM   2535  C  CA  . THR B 1 25  ? -43.915 11.326  -38.090 1.00 32.54  ? 25  THR B CA  1 
ATOM   2536  C  C   . THR B 1 25  ? -42.734 12.262  -38.333 1.00 29.20  ? 25  THR B C   1 
ATOM   2537  O  O   . THR B 1 25  ? -42.405 12.589  -39.480 1.00 29.88  ? 25  THR B O   1 
ATOM   2538  C  CB  . THR B 1 25  ? -43.530 9.900   -38.476 1.00 35.73  ? 25  THR B CB  1 
ATOM   2539  O  OG1 . THR B 1 25  ? -44.692 9.058   -38.426 1.00 45.58  ? 25  THR B OG1 1 
ATOM   2540  C  CG2 . THR B 1 25  ? -42.459 9.376   -37.515 1.00 36.57  ? 25  THR B CG2 1 
ATOM   2541  N  N   . THR B 1 26  ? -42.111 12.693  -37.244 1.00 27.93  ? 26  THR B N   1 
ATOM   2542  C  CA  . THR B 1 26  ? -40.946 13.563  -37.269 1.00 29.52  ? 26  THR B CA  1 
ATOM   2543  C  C   . THR B 1 26  ? -39.842 12.896  -36.471 1.00 25.08  ? 26  THR B C   1 
ATOM   2544  O  O   . THR B 1 26  ? -40.082 12.430  -35.354 1.00 30.63  ? 26  THR B O   1 
ATOM   2545  C  CB  . THR B 1 26  ? -41.256 14.946  -36.648 1.00 29.86  ? 26  THR B CB  1 
ATOM   2546  O  OG1 . THR B 1 26  ? -42.209 15.649  -37.452 1.00 34.45  ? 26  THR B OG1 1 
ATOM   2547  C  CG2 . THR B 1 26  ? -39.999 15.775  -36.501 1.00 23.75  ? 26  THR B CG2 1 
ATOM   2548  N  N   . LEU B 1 27  ? -38.640 12.861  -37.026 1.00 22.53  ? 27  LEU B N   1 
ATOM   2549  C  CA  . LEU B 1 27  ? -37.475 12.428  -36.257 1.00 29.39  ? 27  LEU B CA  1 
ATOM   2550  C  C   . LEU B 1 27  ? -36.252 13.138  -36.821 1.00 20.98  ? 27  LEU B C   1 
ATOM   2551  O  O   . LEU B 1 27  ? -36.367 14.087  -37.606 1.00 22.38  ? 27  LEU B O   1 
ATOM   2552  C  CB  . LEU B 1 27  ? -37.350 10.890  -36.237 1.00 23.47  ? 27  LEU B CB  1 
ATOM   2553  C  CG  . LEU B 1 27  ? -37.555 10.032  -37.487 1.00 24.28  ? 27  LEU B CG  1 
ATOM   2554  C  CD1 . LEU B 1 27  ? -36.491 10.290  -38.515 1.00 30.39  ? 27  LEU B CD1 1 
ATOM   2555  C  CD2 . LEU B 1 27  ? -37.584 8.536   -37.133 1.00 23.12  ? 27  LEU B CD2 1 
ATOM   2556  N  N   . ASN B 1 28  ? -35.080 12.700  -36.410 1.00 17.39  ? 28  ASN B N   1 
ATOM   2557  C  CA  . ASN B 1 28  ? -33.873 13.398  -36.801 1.00 17.94  ? 28  ASN B CA  1 
ATOM   2558  C  C   . ASN B 1 28  ? -33.231 12.721  -37.998 1.00 20.35  ? 28  ASN B C   1 
ATOM   2559  O  O   . ASN B 1 28  ? -33.441 11.526  -38.248 1.00 23.03  ? 28  ASN B O   1 
ATOM   2560  C  CB  . ASN B 1 28  ? -32.872 13.462  -35.656 1.00 21.88  ? 28  ASN B CB  1 
ATOM   2561  C  CG  . ASN B 1 28  ? -33.464 14.046  -34.395 1.00 22.08  ? 28  ASN B CG  1 
ATOM   2562  O  OD1 . ASN B 1 28  ? -33.633 15.267  -34.271 1.00 21.61  ? 28  ASN B OD1 1 
ATOM   2563  N  ND2 . ASN B 1 28  ? -33.762 13.176  -33.437 1.00 16.98  ? 28  ASN B ND2 1 
ATOM   2564  N  N   . GLY B 1 29  ? -32.488 13.522  -38.764 1.00 17.01  ? 29  GLY B N   1 
ATOM   2565  C  CA  . GLY B 1 29  ? -31.662 13.012  -39.832 1.00 15.66  ? 29  GLY B CA  1 
ATOM   2566  C  C   . GLY B 1 29  ? -30.265 13.603  -39.760 1.00 19.90  ? 29  GLY B C   1 
ATOM   2567  O  O   . GLY B 1 29  ? -30.013 14.596  -39.065 1.00 20.39  ? 29  GLY B O   1 
ATOM   2568  N  N   . LEU B 1 30  ? -29.350 12.969  -40.492 1.00 22.25  ? 30  LEU B N   1 
ATOM   2569  C  CA  . LEU B 1 30  ? -27.940 13.354  -40.551 1.00 21.82  ? 30  LEU B CA  1 
ATOM   2570  C  C   . LEU B 1 30  ? -27.638 13.833  -41.960 1.00 19.47  ? 30  LEU B C   1 
ATOM   2571  O  O   . LEU B 1 30  ? -27.717 13.046  -42.913 1.00 18.69  ? 30  LEU B O   1 
ATOM   2572  C  CB  . LEU B 1 30  ? -27.034 12.171  -40.207 1.00 19.13  ? 30  LEU B CB  1 
ATOM   2573  C  CG  . LEU B 1 30  ? -25.544 12.444  -40.020 1.00 15.01  ? 30  LEU B CG  1 
ATOM   2574  C  CD1 . LEU B 1 30  ? -25.363 13.157  -38.708 1.00 15.34  ? 30  LEU B CD1 1 
ATOM   2575  C  CD2 . LEU B 1 30  ? -24.787 11.149  -39.989 1.00 15.29  ? 30  LEU B CD2 1 
ATOM   2576  N  N   . TRP B 1 31  ? -27.285 15.106  -42.088 1.00 18.85  ? 31  TRP B N   1 
ATOM   2577  C  CA  . TRP B 1 31  ? -27.085 15.740  -43.387 1.00 18.61  ? 31  TRP B CA  1 
ATOM   2578  C  C   . TRP B 1 31  ? -25.586 15.777  -43.662 1.00 21.97  ? 31  TRP B C   1 
ATOM   2579  O  O   . TRP B 1 31  ? -24.848 16.523  -43.010 1.00 21.18  ? 31  TRP B O   1 
ATOM   2580  C  CB  . TRP B 1 31  ? -27.692 17.142  -43.393 1.00 19.51  ? 31  TRP B CB  1 
ATOM   2581  C  CG  . TRP B 1 31  ? -27.648 17.913  -44.707 1.00 24.77  ? 31  TRP B CG  1 
ATOM   2582  C  CD1 . TRP B 1 31  ? -27.478 17.406  -45.964 1.00 22.78  ? 31  TRP B CD1 1 
ATOM   2583  C  CD2 . TRP B 1 31  ? -27.765 19.344  -44.863 1.00 24.34  ? 31  TRP B CD2 1 
ATOM   2584  N  NE1 . TRP B 1 31  ? -27.494 18.419  -46.885 1.00 27.04  ? 31  TRP B NE1 1 
ATOM   2585  C  CE2 . TRP B 1 31  ? -27.659 19.621  -46.237 1.00 25.53  ? 31  TRP B CE2 1 
ATOM   2586  C  CE3 . TRP B 1 31  ? -27.948 20.408  -43.968 1.00 21.11  ? 31  TRP B CE3 1 
ATOM   2587  C  CZ2 . TRP B 1 31  ? -27.735 20.922  -46.749 1.00 30.88  ? 31  TRP B CZ2 1 
ATOM   2588  C  CZ3 . TRP B 1 31  ? -28.019 21.703  -44.472 1.00 27.05  ? 31  TRP B CZ3 1 
ATOM   2589  C  CH2 . TRP B 1 31  ? -27.918 21.950  -45.853 1.00 27.99  ? 31  TRP B CH2 1 
ATOM   2590  N  N   . LEU B 1 32  ? -25.127 14.953  -44.607 1.00 20.74  ? 32  LEU B N   1 
ATOM   2591  C  CA  . LEU B 1 32  ? -23.716 14.911  -44.973 1.00 22.62  ? 32  LEU B CA  1 
ATOM   2592  C  C   . LEU B 1 32  ? -23.582 15.024  -46.481 1.00 24.20  ? 32  LEU B C   1 
ATOM   2593  O  O   . LEU B 1 32  ? -24.137 14.200  -47.216 1.00 22.14  ? 32  LEU B O   1 
ATOM   2594  C  CB  . LEU B 1 32  ? -23.060 13.621  -44.474 1.00 25.05  ? 32  LEU B CB  1 
ATOM   2595  C  CG  . LEU B 1 32  ? -23.180 13.343  -42.977 1.00 19.63  ? 32  LEU B CG  1 
ATOM   2596  C  CD1 . LEU B 1 32  ? -22.820 11.900  -42.773 1.00 22.28  ? 32  LEU B CD1 1 
ATOM   2597  C  CD2 . LEU B 1 32  ? -22.292 14.267  -42.143 1.00 15.36  ? 32  LEU B CD2 1 
ATOM   2598  N  N   . ASP B 1 33  ? -22.816 16.018  -46.937 1.00 26.52  ? 33  ASP B N   1 
ATOM   2599  C  CA  . ASP B 1 33  ? -22.707 16.341  -48.367 1.00 27.19  ? 33  ASP B CA  1 
ATOM   2600  C  C   . ASP B 1 33  ? -24.135 16.598  -48.839 1.00 23.75  ? 33  ASP B C   1 
ATOM   2601  O  O   . ASP B 1 33  ? -24.853 17.371  -48.188 1.00 23.52  ? 33  ASP B O   1 
ATOM   2602  C  CB  . ASP B 1 33  ? -21.956 15.217  -49.098 1.00 32.59  ? 33  ASP B CB  1 
ATOM   2603  C  CG  . ASP B 1 33  ? -20.582 14.901  -48.468 1.00 41.05  ? 33  ASP B CG  1 
ATOM   2604  O  OD1 . ASP B 1 33  ? -19.824 15.859  -48.174 1.00 43.22  ? 33  ASP B OD1 1 
ATOM   2605  O  OD2 . ASP B 1 33  ? -20.277 13.692  -48.230 1.00 38.48  ? 33  ASP B OD2 1 
ATOM   2606  N  N   . ASP B 1 34  ? -24.605 15.946  -49.897 1.00 22.21  ? 34  ASP B N   1 
ATOM   2607  C  CA  . ASP B 1 34  ? -25.947 16.156  -50.420 1.00 27.18  ? 34  ASP B CA  1 
ATOM   2608  C  C   . ASP B 1 34  ? -26.877 14.979  -50.118 1.00 27.43  ? 34  ASP B C   1 
ATOM   2609  O  O   . ASP B 1 34  ? -27.793 14.700  -50.896 1.00 27.02  ? 34  ASP B O   1 
ATOM   2610  C  CB  . ASP B 1 34  ? -25.894 16.424  -51.926 1.00 25.90  ? 34  ASP B CB  1 
ATOM   2611  C  CG  . ASP B 1 34  ? -25.285 15.268  -52.700 1.00 33.51  ? 34  ASP B CG  1 
ATOM   2612  O  OD1 . ASP B 1 34  ? -24.461 14.515  -52.119 1.00 32.51  ? 34  ASP B OD1 1 
ATOM   2613  O  OD2 . ASP B 1 34  ? -25.618 15.123  -53.892 1.00 32.42  ? 34  ASP B OD2 1 
ATOM   2614  N  N   . VAL B 1 35  ? -26.630 14.255  -49.022 1.00 24.45  ? 35  VAL B N   1 
ATOM   2615  C  CA  . VAL B 1 35  ? -27.461 13.125  -48.609 1.00 26.40  ? 35  VAL B CA  1 
ATOM   2616  C  C   . VAL B 1 35  ? -27.853 13.323  -47.149 1.00 21.23  ? 35  VAL B C   1 
ATOM   2617  O  O   . VAL B 1 35  ? -27.027 13.723  -46.321 1.00 23.16  ? 35  VAL B O   1 
ATOM   2618  C  CB  . VAL B 1 35  ? -26.755 11.763  -48.796 1.00 25.49  ? 35  VAL B CB  1 
ATOM   2619  C  CG1 . VAL B 1 35  ? -27.660 10.628  -48.327 1.00 24.18  ? 35  VAL B CG1 1 
ATOM   2620  C  CG2 . VAL B 1 35  ? -26.376 11.556  -50.248 1.00 22.37  ? 35  VAL B CG2 1 
ATOM   2621  N  N   . VAL B 1 36  ? -29.115 13.043  -46.844 1.00 19.42  ? 36  VAL B N   1 
ATOM   2622  C  CA  . VAL B 1 36  ? -29.653 13.045  -45.483 1.00 24.82  ? 36  VAL B CA  1 
ATOM   2623  C  C   . VAL B 1 36  ? -29.938 11.601  -45.094 1.00 20.79  ? 36  VAL B C   1 
ATOM   2624  O  O   . VAL B 1 36  ? -30.640 10.895  -45.821 1.00 21.27  ? 36  VAL B O   1 
ATOM   2625  C  CB  . VAL B 1 36  ? -30.926 13.905  -45.390 1.00 19.82  ? 36  VAL B CB  1 
ATOM   2626  C  CG1 . VAL B 1 36  ? -31.658 13.673  -44.082 1.00 18.52  ? 36  VAL B CG1 1 
ATOM   2627  C  CG2 . VAL B 1 36  ? -30.557 15.346  -45.554 1.00 19.30  ? 36  VAL B CG2 1 
ATOM   2628  N  N   . TYR B 1 37  ? -29.372 11.153  -43.971 1.00 23.77  ? 37  TYR B N   1 
ATOM   2629  C  CA  . TYR B 1 37  ? -29.611 9.801   -43.455 1.00 26.93  ? 37  TYR B CA  1 
ATOM   2630  C  C   . TYR B 1 37  ? -30.559 9.830   -42.269 1.00 21.72  ? 37  TYR B C   1 
ATOM   2631  O  O   . TYR B 1 37  ? -30.397 10.657  -41.369 1.00 26.83  ? 37  TYR B O   1 
ATOM   2632  C  CB  . TYR B 1 37  ? -28.310 9.125   -43.019 1.00 23.85  ? 37  TYR B CB  1 
ATOM   2633  C  CG  . TYR B 1 37  ? -27.250 9.130   -44.077 1.00 23.86  ? 37  TYR B CG  1 
ATOM   2634  C  CD1 . TYR B 1 37  ? -26.491 10.270  -44.326 1.00 21.04  ? 37  TYR B CD1 1 
ATOM   2635  C  CD2 . TYR B 1 37  ? -27.029 8.003   -44.863 1.00 22.81  ? 37  TYR B CD2 1 
ATOM   2636  C  CE1 . TYR B 1 37  ? -25.515 10.272  -45.298 1.00 23.12  ? 37  TYR B CE1 1 
ATOM   2637  C  CE2 . TYR B 1 37  ? -26.051 8.005   -45.848 1.00 23.08  ? 37  TYR B CE2 1 
ATOM   2638  C  CZ  . TYR B 1 37  ? -25.307 9.142   -46.054 1.00 20.89  ? 37  TYR B CZ  1 
ATOM   2639  O  OH  . TYR B 1 37  ? -24.352 9.160   -47.030 1.00 29.75  ? 37  TYR B OH  1 
ATOM   2640  N  N   . CYS B 1 38  ? -31.530 8.917   -42.252 1.00 21.30  ? 38  CYS B N   1 
ATOM   2641  C  CA  . CYS B 1 38  ? -32.467 8.843   -41.139 1.00 21.35  ? 38  CYS B CA  1 
ATOM   2642  C  C   . CYS B 1 38  ? -33.053 7.431   -41.077 1.00 25.02  ? 38  CYS B C   1 
ATOM   2643  O  O   . CYS B 1 38  ? -32.901 6.645   -42.022 1.00 21.58  ? 38  CYS B O   1 
ATOM   2644  C  CB  . CYS B 1 38  ? -33.572 9.905   -41.269 1.00 18.20  ? 38  CYS B CB  1 
ATOM   2645  S  SG  . CYS B 1 38  ? -34.759 9.675   -42.593 1.00 25.11  ? 38  CYS B SG  1 
ATOM   2646  N  N   . PRO B 1 39  ? -33.685 7.061   -39.959 1.00 24.94  ? 39  PRO B N   1 
ATOM   2647  C  CA  . PRO B 1 39  ? -34.293 5.727   -39.882 1.00 20.23  ? 39  PRO B CA  1 
ATOM   2648  C  C   . PRO B 1 39  ? -35.456 5.620   -40.853 1.00 26.42  ? 39  PRO B C   1 
ATOM   2649  O  O   . PRO B 1 39  ? -36.263 6.551   -40.997 1.00 22.78  ? 39  PRO B O   1 
ATOM   2650  C  CB  . PRO B 1 39  ? -34.765 5.628   -38.427 1.00 23.89  ? 39  PRO B CB  1 
ATOM   2651  C  CG  . PRO B 1 39  ? -33.966 6.683   -37.682 1.00 22.91  ? 39  PRO B CG  1 
ATOM   2652  C  CD  . PRO B 1 39  ? -33.760 7.781   -38.670 1.00 22.12  ? 39  PRO B CD  1 
ATOM   2653  N  N   . ARG B 1 40  ? -35.535 4.466   -41.530 1.00 23.35  ? 40  ARG B N   1 
ATOM   2654  C  CA  . ARG B 1 40  ? -36.571 4.289   -42.531 1.00 20.26  ? 40  ARG B CA  1 
ATOM   2655  C  C   . ARG B 1 40  ? -37.961 4.340   -41.915 1.00 29.41  ? 40  ARG B C   1 
ATOM   2656  O  O   . ARG B 1 40  ? -38.935 4.624   -42.629 1.00 29.35  ? 40  ARG B O   1 
ATOM   2657  C  CB  . ARG B 1 40  ? -36.374 2.972   -43.290 1.00 25.88  ? 40  ARG B CB  1 
ATOM   2658  C  CG  . ARG B 1 40  ? -36.671 1.684   -42.503 1.00 24.18  ? 40  ARG B CG  1 
ATOM   2659  C  CD  . ARG B 1 40  ? -36.439 0.466   -43.379 1.00 24.00  ? 40  ARG B CD  1 
ATOM   2660  N  NE  . ARG B 1 40  ? -36.586 -0.816  -42.685 1.00 28.76  ? 40  ARG B NE  1 
ATOM   2661  C  CZ  . ARG B 1 40  ? -36.485 -2.000  -43.282 1.00 31.36  ? 40  ARG B CZ  1 
ATOM   2662  N  NH1 . ARG B 1 40  ? -36.250 -2.102  -44.584 1.00 26.63  ? 40  ARG B NH1 1 
ATOM   2663  N  NH2 . ARG B 1 40  ? -36.650 -3.113  -42.563 1.00 28.46  ? 40  ARG B NH2 1 
ATOM   2664  N  N   . HIS B 1 41  ? -38.088 4.065   -40.592 1.00 27.97  ? 41  HIS B N   1 
ATOM   2665  C  CA  . HIS B 1 41  ? -39.452 4.099   -40.077 1.00 29.55  ? 41  HIS B CA  1 
ATOM   2666  C  C   . HIS B 1 41  ? -40.028 5.519   -40.004 1.00 25.95  ? 41  HIS B C   1 
ATOM   2667  O  O   . HIS B 1 41  ? -41.130 5.652   -39.526 1.00 28.52  ? 41  HIS B O   1 
ATOM   2668  C  CB  . HIS B 1 41  ? -39.543 3.400   -38.703 1.00 30.43  ? 41  HIS B CB  1 
ATOM   2669  C  CG  . HIS B 1 41  ? -38.825 4.093   -37.581 1.00 23.35  ? 41  HIS B CG  1 
ATOM   2670  N  ND1 . HIS B 1 41  ? -37.583 3.694   -37.134 1.00 22.81  ? 41  HIS B ND1 1 
ATOM   2671  C  CD2 . HIS B 1 41  ? -39.201 5.118   -36.778 1.00 22.18  ? 41  HIS B CD2 1 
ATOM   2672  C  CE1 . HIS B 1 41  ? -37.209 4.465   -36.126 1.00 21.44  ? 41  HIS B CE1 1 
ATOM   2673  N  NE2 . HIS B 1 41  ? -38.178 5.330   -35.883 1.00 20.32  ? 41  HIS B NE2 1 
ATOM   2674  N  N   . VAL B 1 42  ? -39.366 6.562   -40.512 1.00 27.57  ? 42  VAL B N   1 
ATOM   2675  C  CA  . VAL B 1 42  ? -40.025 7.847   -40.724 1.00 29.26  ? 42  VAL B CA  1 
ATOM   2676  C  C   . VAL B 1 42  ? -41.189 7.734   -41.699 1.00 34.09  ? 42  VAL B C   1 
ATOM   2677  O  O   . VAL B 1 42  ? -42.093 8.579   -41.679 1.00 35.13  ? 42  VAL B O   1 
ATOM   2678  C  CB  . VAL B 1 42  ? -39.018 8.918   -41.210 1.00 26.39  ? 42  VAL B CB  1 
ATOM   2679  C  CG1 . VAL B 1 42  ? -38.592 8.664   -42.662 1.00 23.19  ? 42  VAL B CG1 1 
ATOM   2680  C  CG2 . VAL B 1 42  ? -39.610 10.317  -41.042 1.00 30.74  ? 42  VAL B CG2 1 
ATOM   2681  N  N   . ILE B 1 43  ? -41.221 6.697   -42.546 1.00 31.86  ? 43  ILE B N   1 
ATOM   2682  C  CA  . ILE B 1 43  ? -42.302 6.605   -43.518 1.00 36.54  ? 43  ILE B CA  1 
ATOM   2683  C  C   . ILE B 1 43  ? -43.532 5.893   -42.967 1.00 38.17  ? 43  ILE B C   1 
ATOM   2684  O  O   . ILE B 1 43  ? -44.562 5.854   -43.652 1.00 49.26  ? 43  ILE B O   1 
ATOM   2685  C  CB  . ILE B 1 43  ? -41.839 5.921   -44.823 1.00 39.06  ? 43  ILE B CB  1 
ATOM   2686  C  CG1 . ILE B 1 43  ? -41.791 4.408   -44.688 1.00 39.21  ? 43  ILE B CG1 1 
ATOM   2687  C  CG2 . ILE B 1 43  ? -40.471 6.412   -45.215 1.00 32.83  ? 43  ILE B CG2 1 
ATOM   2688  C  CD1 . ILE B 1 43  ? -41.199 3.751   -45.895 1.00 39.22  ? 43  ILE B CD1 1 
ATOM   2689  N  N   . CYS B 1 44  ? -43.480 5.384   -41.735 1.00 46.94  ? 44  CYS B N   1 
ATOM   2690  C  CA  . CYS B 1 44  ? -44.589 4.669   -41.104 1.00 59.27  ? 44  CYS B CA  1 
ATOM   2691  C  C   . CYS B 1 44  ? -45.571 5.596   -40.389 1.00 70.02  ? 44  CYS B C   1 
ATOM   2692  O  O   . CYS B 1 44  ? -45.209 6.675   -39.909 1.00 67.97  ? 44  CYS B O   1 
ATOM   2693  C  CB  . CYS B 1 44  ? -44.071 3.658   -40.079 1.00 55.51  ? 44  CYS B CB  1 
ATOM   2694  S  SG  . CYS B 1 44  ? -43.022 2.361   -40.731 1.00 60.78  ? 44  CYS B SG  1 
ATOM   2695  N  N   . THR B 1 45  ? -46.826 5.150   -40.319 1.00 82.28  ? 45  THR B N   1 
ATOM   2696  C  CA  . THR B 1 45  ? -47.806 5.673   -39.377 1.00 96.14  ? 45  THR B CA  1 
ATOM   2697  C  C   . THR B 1 45  ? -47.740 4.876   -38.072 1.00 100.40 ? 45  THR B C   1 
ATOM   2698  O  O   . THR B 1 45  ? -47.120 3.813   -37.997 1.00 105.33 ? 45  THR B O   1 
ATOM   2699  C  CB  . THR B 1 45  ? -49.222 5.612   -39.961 1.00 103.45 ? 45  THR B CB  1 
ATOM   2700  O  OG1 . THR B 1 45  ? -49.695 4.257   -39.951 1.00 102.89 ? 45  THR B OG1 1 
ATOM   2701  C  CG2 . THR B 1 45  ? -49.237 6.143   -41.396 1.00 94.67  ? 45  THR B CG2 1 
ATOM   2702  N  N   . SER B 1 46  ? -48.391 5.398   -37.028 1.00 105.09 ? 46  SER B N   1 
ATOM   2703  C  CA  . SER B 1 46  ? -48.463 4.657   -35.769 1.00 111.50 ? 46  SER B CA  1 
ATOM   2704  C  C   . SER B 1 46  ? -49.214 3.340   -35.931 1.00 114.32 ? 46  SER B C   1 
ATOM   2705  O  O   . SER B 1 46  ? -48.970 2.388   -35.179 1.00 114.10 ? 46  SER B O   1 
ATOM   2706  C  CB  . SER B 1 46  ? -49.114 5.513   -34.681 1.00 106.75 ? 46  SER B CB  1 
ATOM   2707  O  OG  . SER B 1 46  ? -48.207 6.477   -34.176 1.00 100.53 ? 46  SER B OG  1 
ATOM   2708  N  N   . GLU B 1 47  ? -50.134 3.271   -36.897 1.00 113.22 ? 47  GLU B N   1 
ATOM   2709  C  CA  . GLU B 1 47  ? -50.886 2.045   -37.150 1.00 113.90 ? 47  GLU B CA  1 
ATOM   2710  C  C   . GLU B 1 47  ? -49.972 0.915   -37.615 1.00 116.79 ? 47  GLU B C   1 
ATOM   2711  O  O   . GLU B 1 47  ? -49.830 -0.108  -36.935 1.00 118.73 ? 47  GLU B O   1 
ATOM   2712  C  CB  . GLU B 1 47  ? -51.987 2.322   -38.174 1.00 115.28 ? 47  GLU B CB  1 
ATOM   2713  C  CG  . GLU B 1 47  ? -52.861 3.511   -37.803 1.00 110.98 ? 47  GLU B CG  1 
ATOM   2714  C  CD  . GLU B 1 47  ? -53.464 4.208   -39.007 1.00 110.98 ? 47  GLU B CD  1 
ATOM   2715  O  OE1 . GLU B 1 47  ? -52.920 4.069   -40.124 1.00 112.74 ? 47  GLU B OE1 1 
ATOM   2716  O  OE2 . GLU B 1 47  ? -54.490 4.898   -38.831 1.00 108.22 ? 47  GLU B OE2 1 
ATOM   2717  N  N   . ASP B 1 48  ? -49.354 1.077   -38.784 1.00 118.60 ? 48  ASP B N   1 
ATOM   2718  C  CA  . ASP B 1 48  ? -48.591 0.002   -39.410 1.00 118.11 ? 48  ASP B CA  1 
ATOM   2719  C  C   . ASP B 1 48  ? -47.224 -0.211  -38.768 1.00 112.10 ? 48  ASP B C   1 
ATOM   2720  O  O   . ASP B 1 48  ? -46.281 -0.625  -39.448 1.00 105.95 ? 48  ASP B O   1 
ATOM   2721  C  CB  . ASP B 1 48  ? -48.410 0.288   -40.901 1.00 112.90 ? 48  ASP B CB  1 
ATOM   2722  C  CG  . ASP B 1 48  ? -49.631 -0.065  -41.710 1.00 111.80 ? 48  ASP B CG  1 
ATOM   2723  O  OD1 . ASP B 1 48  ? -50.666 -0.404  -41.095 1.00 111.01 ? 48  ASP B OD1 1 
ATOM   2724  O  OD2 . ASP B 1 48  ? -49.556 -0.000  -42.956 1.00 103.37 ? 48  ASP B OD2 1 
ATOM   2725  N  N   . MET B 1 49  ? -47.102 0.043   -37.464 1.00 114.32 ? 49  MET B N   1 
ATOM   2726  C  CA  . MET B 1 49  ? -45.849 -0.235  -36.773 1.00 111.68 ? 49  MET B CA  1 
ATOM   2727  C  C   . MET B 1 49  ? -45.740 -1.690  -36.338 1.00 107.12 ? 49  MET B C   1 
ATOM   2728  O  O   . MET B 1 49  ? -44.632 -2.155  -36.049 1.00 101.62 ? 49  MET B O   1 
ATOM   2729  C  CB  . MET B 1 49  ? -45.698 0.675   -35.547 1.00 111.30 ? 49  MET B CB  1 
ATOM   2730  C  CG  . MET B 1 49  ? -45.100 2.052   -35.824 1.00 119.44 ? 49  MET B CG  1 
ATOM   2731  S  SD  . MET B 1 49  ? -43.333 2.025   -36.201 1.00 116.67 ? 49  MET B SD  1 
ATOM   2732  C  CE  . MET B 1 49  ? -42.947 3.776   -36.193 1.00 109.92 ? 49  MET B CE  1 
ATOM   2733  N  N   . LEU B 1 50  ? -46.856 -2.421  -36.309 1.00 104.39 ? 50  LEU B N   1 
ATOM   2734  C  CA  . LEU B 1 50  ? -46.817 -3.804  -35.853 1.00 99.76  ? 50  LEU B CA  1 
ATOM   2735  C  C   . LEU B 1 50  ? -46.033 -4.679  -36.823 1.00 93.71  ? 50  LEU B C   1 
ATOM   2736  O  O   . LEU B 1 50  ? -45.156 -5.447  -36.410 1.00 90.00  ? 50  LEU B O   1 
ATOM   2737  C  CB  . LEU B 1 50  ? -48.238 -4.329  -35.657 1.00 107.99 ? 50  LEU B CB  1 
ATOM   2738  C  CG  . LEU B 1 50  ? -48.897 -3.883  -34.347 1.00 110.25 ? 50  LEU B CG  1 
ATOM   2739  C  CD1 . LEU B 1 50  ? -50.328 -4.395  -34.234 1.00 108.63 ? 50  LEU B CD1 1 
ATOM   2740  C  CD2 . LEU B 1 50  ? -48.070 -4.328  -33.149 1.00 101.79 ? 50  LEU B CD2 1 
ATOM   2741  N  N   . ASN B 1 51  ? -46.308 -4.554  -38.120 1.00 91.09  ? 51  ASN B N   1 
ATOM   2742  C  CA  . ASN B 1 51  ? -45.610 -5.337  -39.142 1.00 87.04  ? 51  ASN B CA  1 
ATOM   2743  C  C   . ASN B 1 51  ? -45.528 -4.515  -40.423 1.00 79.46  ? 51  ASN B C   1 
ATOM   2744  O  O   . ASN B 1 51  ? -46.330 -4.681  -41.349 1.00 76.25  ? 51  ASN B O   1 
ATOM   2745  C  CB  . ASN B 1 51  ? -46.305 -6.680  -39.385 1.00 88.58  ? 51  ASN B CB  1 
ATOM   2746  C  CG  . ASN B 1 51  ? -45.627 -7.837  -38.646 1.00 85.62  ? 51  ASN B CG  1 
ATOM   2747  O  OD1 . ASN B 1 51  ? -44.633 -8.394  -39.111 1.00 84.86  ? 51  ASN B OD1 1 
ATOM   2748  N  ND2 . ASN B 1 51  ? -46.169 -8.197  -37.487 1.00 82.29  ? 51  ASN B ND2 1 
ATOM   2749  N  N   . PRO B 1 52  ? -44.569 -3.591  -40.496 1.00 78.95  ? 52  PRO B N   1 
ATOM   2750  C  CA  . PRO B 1 52  ? -44.482 -2.687  -41.654 1.00 69.46  ? 52  PRO B CA  1 
ATOM   2751  C  C   . PRO B 1 52  ? -43.705 -3.318  -42.801 1.00 64.14  ? 52  PRO B C   1 
ATOM   2752  O  O   . PRO B 1 52  ? -42.638 -3.906  -42.599 1.00 62.95  ? 52  PRO B O   1 
ATOM   2753  C  CB  . PRO B 1 52  ? -43.744 -1.466  -41.095 1.00 60.94  ? 52  PRO B CB  1 
ATOM   2754  C  CG  . PRO B 1 52  ? -42.892 -2.028  -40.004 1.00 63.29  ? 52  PRO B CG  1 
ATOM   2755  C  CD  . PRO B 1 52  ? -43.605 -3.234  -39.441 1.00 76.30  ? 52  PRO B CD  1 
ATOM   2756  N  N   . ASN B 1 53  ? -44.258 -3.204  -44.008 1.00 60.54  ? 53  ASN B N   1 
ATOM   2757  C  CA  . ASN B 1 53  ? -43.579 -3.590  -45.245 1.00 52.21  ? 53  ASN B CA  1 
ATOM   2758  C  C   . ASN B 1 53  ? -42.932 -2.329  -45.801 1.00 50.64  ? 53  ASN B C   1 
ATOM   2759  O  O   . ASN B 1 53  ? -43.544 -1.580  -46.559 1.00 49.13  ? 53  ASN B O   1 
ATOM   2760  C  CB  . ASN B 1 53  ? -44.572 -4.198  -46.224 1.00 54.30  ? 53  ASN B CB  1 
ATOM   2761  C  CG  . ASN B 1 53  ? -43.907 -4.792  -47.447 1.00 62.71  ? 53  ASN B CG  1 
ATOM   2762  O  OD1 . ASN B 1 53  ? -42.826 -4.363  -47.859 1.00 64.12  ? 53  ASN B OD1 1 
ATOM   2763  N  ND2 . ASN B 1 53  ? -44.576 -5.760  -48.066 1.00 61.21  ? 53  ASN B ND2 1 
ATOM   2764  N  N   . TYR B 1 54  ? -41.668 -2.101  -45.439 1.00 46.02  ? 54  TYR B N   1 
ATOM   2765  C  CA  . TYR B 1 54  ? -41.056 -0.800  -45.696 1.00 48.68  ? 54  TYR B CA  1 
ATOM   2766  C  C   . TYR B 1 54  ? -40.884 -0.524  -47.184 1.00 50.02  ? 54  TYR B C   1 
ATOM   2767  O  O   . TYR B 1 54  ? -41.114 0.600   -47.640 1.00 46.80  ? 54  TYR B O   1 
ATOM   2768  C  CB  . TYR B 1 54  ? -39.715 -0.708  -44.983 1.00 42.72  ? 54  TYR B CB  1 
ATOM   2769  C  CG  . TYR B 1 54  ? -39.871 -0.520  -43.502 1.00 38.51  ? 54  TYR B CG  1 
ATOM   2770  C  CD1 . TYR B 1 54  ? -40.243 0.696   -42.989 1.00 35.04  ? 54  TYR B CD1 1 
ATOM   2771  C  CD2 . TYR B 1 54  ? -39.630 -1.559  -42.617 1.00 40.20  ? 54  TYR B CD2 1 
ATOM   2772  C  CE1 . TYR B 1 54  ? -40.382 0.873   -41.646 1.00 41.13  ? 54  TYR B CE1 1 
ATOM   2773  C  CE2 . TYR B 1 54  ? -39.760 -1.382  -41.253 1.00 37.23  ? 54  TYR B CE2 1 
ATOM   2774  C  CZ  . TYR B 1 54  ? -40.144 -0.163  -40.776 1.00 39.02  ? 54  TYR B CZ  1 
ATOM   2775  O  OH  . TYR B 1 54  ? -40.290 0.046   -39.419 1.00 44.23  ? 54  TYR B OH  1 
ATOM   2776  N  N   . GLU B 1 55  ? -40.492 -1.538  -47.953 1.00 49.81  ? 55  GLU B N   1 
ATOM   2777  C  CA  . GLU B 1 55  ? -40.346 -1.387  -49.398 1.00 51.45  ? 55  GLU B CA  1 
ATOM   2778  C  C   . GLU B 1 55  ? -41.655 -0.974  -50.052 1.00 58.88  ? 55  GLU B C   1 
ATOM   2779  O  O   . GLU B 1 55  ? -41.672 -0.100  -50.927 1.00 62.98  ? 55  GLU B O   1 
ATOM   2780  C  CB  . GLU B 1 55  ? -39.837 -2.695  -49.999 1.00 46.66  ? 55  GLU B CB  1 
ATOM   2781  C  CG  . GLU B 1 55  ? -38.416 -3.059  -49.596 1.00 49.99  ? 55  GLU B CG  1 
ATOM   2782  C  CD  . GLU B 1 55  ? -38.262 -3.516  -48.145 1.00 52.51  ? 55  GLU B CD  1 
ATOM   2783  O  OE1 . GLU B 1 55  ? -39.280 -3.632  -47.424 1.00 52.16  ? 55  GLU B OE1 1 
ATOM   2784  O  OE2 . GLU B 1 55  ? -37.107 -3.771  -47.721 1.00 46.53  ? 55  GLU B OE2 1 
ATOM   2785  N  N   . ASP B 1 56  ? -42.760 -1.601  -49.641 1.00 56.49  ? 56  ASP B N   1 
ATOM   2786  C  CA  . ASP B 1 56  ? -44.071 -1.259  -50.182 1.00 57.84  ? 56  ASP B CA  1 
ATOM   2787  C  C   . ASP B 1 56  ? -44.474 0.170   -49.821 1.00 60.46  ? 56  ASP B C   1 
ATOM   2788  O  O   . ASP B 1 56  ? -44.996 0.906   -50.669 1.00 62.78  ? 56  ASP B O   1 
ATOM   2789  C  CB  . ASP B 1 56  ? -45.116 -2.263  -49.676 1.00 60.94  ? 56  ASP B CB  1 
ATOM   2790  C  CG  . ASP B 1 56  ? -44.974 -3.645  -50.321 1.00 64.28  ? 56  ASP B CG  1 
ATOM   2791  O  OD1 . ASP B 1 56  ? -44.112 -3.814  -51.215 1.00 62.36  ? 56  ASP B OD1 1 
ATOM   2792  O  OD2 . ASP B 1 56  ? -45.722 -4.567  -49.918 1.00 66.33  ? 56  ASP B OD2 1 
ATOM   2793  N  N   . LEU B 1 57  ? -44.240 0.587   -48.573 1.00 61.59  ? 57  LEU B N   1 
ATOM   2794  C  CA  . LEU B 1 57  ? -44.580 1.953   -48.182 1.00 57.55  ? 57  LEU B CA  1 
ATOM   2795  C  C   . LEU B 1 57  ? -43.757 2.966   -48.968 1.00 54.52  ? 57  LEU B C   1 
ATOM   2796  O  O   . LEU B 1 57  ? -44.270 4.016   -49.373 1.00 54.23  ? 57  LEU B O   1 
ATOM   2797  C  CB  . LEU B 1 57  ? -44.378 2.139   -46.676 1.00 53.32  ? 57  LEU B CB  1 
ATOM   2798  C  CG  . LEU B 1 57  ? -45.275 1.332   -45.728 1.00 50.59  ? 57  LEU B CG  1 
ATOM   2799  C  CD1 . LEU B 1 57  ? -44.715 1.336   -44.316 1.00 48.89  ? 57  LEU B CD1 1 
ATOM   2800  C  CD2 . LEU B 1 57  ? -46.684 1.870   -45.728 1.00 56.82  ? 57  LEU B CD2 1 
ATOM   2801  N  N   . LEU B 1 58  ? -42.486 2.645   -49.230 1.00 57.50  ? 58  LEU B N   1 
ATOM   2802  C  CA  . LEU B 1 58  ? -41.586 3.599   -49.876 1.00 54.93  ? 58  LEU B CA  1 
ATOM   2803  C  C   . LEU B 1 58  ? -41.977 3.835   -51.328 1.00 59.62  ? 58  LEU B C   1 
ATOM   2804  O  O   . LEU B 1 58  ? -41.806 4.944   -51.850 1.00 64.08  ? 58  LEU B O   1 
ATOM   2805  C  CB  . LEU B 1 58  ? -40.139 3.112   -49.780 1.00 49.38  ? 58  LEU B CB  1 
ATOM   2806  C  CG  . LEU B 1 58  ? -39.022 4.051   -50.253 1.00 42.20  ? 58  LEU B CG  1 
ATOM   2807  C  CD1 . LEU B 1 58  ? -39.075 5.394   -49.557 1.00 37.47  ? 58  LEU B CD1 1 
ATOM   2808  C  CD2 . LEU B 1 58  ? -37.656 3.398   -50.051 1.00 35.96  ? 58  LEU B CD2 1 
ATOM   2809  N  N   . ILE B 1 59  ? -42.457 2.796   -52.015 1.00 58.35  ? 59  ILE B N   1 
ATOM   2810  C  CA  . ILE B 1 59  ? -42.804 2.978   -53.416 1.00 59.48  ? 59  ILE B CA  1 
ATOM   2811  C  C   . ILE B 1 59  ? -44.007 3.905   -53.558 1.00 56.91  ? 59  ILE B C   1 
ATOM   2812  O  O   . ILE B 1 59  ? -44.186 4.521   -54.616 1.00 64.54  ? 59  ILE B O   1 
ATOM   2813  C  CB  . ILE B 1 59  ? -43.024 1.611   -54.099 1.00 58.31  ? 59  ILE B CB  1 
ATOM   2814  C  CG1 . ILE B 1 59  ? -42.801 1.748   -55.597 1.00 65.22  ? 59  ILE B CG1 1 
ATOM   2815  C  CG2 . ILE B 1 59  ? -44.423 1.083   -53.848 1.00 56.00  ? 59  ILE B CG2 1 
ATOM   2816  C  CD1 . ILE B 1 59  ? -41.433 2.346   -55.933 1.00 67.45  ? 59  ILE B CD1 1 
ATOM   2817  N  N   . ARG B 1 60  ? -44.827 4.041   -52.508 1.00 62.12  ? 60  ARG B N   1 
ATOM   2818  C  CA  . ARG B 1 60  ? -45.949 4.978   -52.498 1.00 60.16  ? 60  ARG B CA  1 
ATOM   2819  C  C   . ARG B 1 60  ? -45.545 6.416   -52.177 1.00 64.47  ? 60  ARG B C   1 
ATOM   2820  O  O   . ARG B 1 60  ? -46.407 7.299   -52.224 1.00 65.11  ? 60  ARG B O   1 
ATOM   2821  C  CB  . ARG B 1 60  ? -47.040 4.543   -51.505 1.00 68.67  ? 60  ARG B CB  1 
ATOM   2822  C  CG  . ARG B 1 60  ? -47.768 3.222   -51.809 1.00 70.20  ? 60  ARG B CG  1 
ATOM   2823  C  CD  . ARG B 1 60  ? -49.229 3.341   -51.312 1.00 79.32  ? 60  ARG B CD  1 
ATOM   2824  N  NE  . ARG B 1 60  ? -49.535 2.635   -50.072 1.00 78.07  ? 60  ARG B NE  1 
ATOM   2825  C  CZ  . ARG B 1 60  ? -49.962 1.380   -50.005 1.00 84.89  ? 60  ARG B CZ  1 
ATOM   2826  N  NH1 . ARG B 1 60  ? -50.191 0.669   -51.100 1.00 74.75  ? 60  ARG B NH1 1 
ATOM   2827  N  NH2 . ARG B 1 60  ? -50.186 0.831   -48.811 1.00 77.07  ? 60  ARG B NH2 1 
ATOM   2828  N  N   . LYS B 1 61  ? -44.280 6.685   -51.857 1.00 59.34  ? 61  LYS B N   1 
ATOM   2829  C  CA  . LYS B 1 61  ? -43.846 8.029   -51.501 1.00 61.35  ? 61  LYS B CA  1 
ATOM   2830  C  C   . LYS B 1 61  ? -43.112 8.690   -52.665 1.00 56.06  ? 61  LYS B C   1 
ATOM   2831  O  O   . LYS B 1 61  ? -42.510 8.024   -53.510 1.00 52.69  ? 61  LYS B O   1 
ATOM   2832  C  CB  . LYS B 1 61  ? -42.941 8.018   -50.262 1.00 56.35  ? 61  LYS B CB  1 
ATOM   2833  C  CG  . LYS B 1 61  ? -43.516 7.323   -49.026 1.00 55.98  ? 61  LYS B CG  1 
ATOM   2834  C  CD  . LYS B 1 61  ? -44.512 8.205   -48.281 1.00 58.34  ? 61  LYS B CD  1 
ATOM   2835  C  CE  . LYS B 1 61  ? -45.097 7.470   -47.075 1.00 61.05  ? 61  LYS B CE  1 
ATOM   2836  N  NZ  . LYS B 1 61  ? -46.323 8.113   -46.518 1.00 56.31  ? 61  LYS B NZ  1 
ATOM   2837  N  N   . SER B 1 62  ? -43.181 10.017  -52.700 1.00 51.18  ? 62  SER B N   1 
ATOM   2838  C  CA  . SER B 1 62  ? -42.432 10.840  -53.635 1.00 50.39  ? 62  SER B CA  1 
ATOM   2839  C  C   . SER B 1 62  ? -41.450 11.721  -52.870 1.00 44.29  ? 62  SER B C   1 
ATOM   2840  O  O   . SER B 1 62  ? -41.542 11.885  -51.652 1.00 43.67  ? 62  SER B O   1 
ATOM   2841  C  CB  . SER B 1 62  ? -43.372 11.720  -54.474 1.00 49.96  ? 62  SER B CB  1 
ATOM   2842  O  OG  . SER B 1 62  ? -44.281 10.947  -55.241 1.00 59.17  ? 62  SER B OG  1 
ATOM   2843  N  N   . ASN B 1 63  ? -40.520 12.316  -53.620 1.00 45.75  ? 63  ASN B N   1 
ATOM   2844  C  CA  . ASN B 1 63  ? -39.516 13.198  -53.033 1.00 37.98  ? 63  ASN B CA  1 
ATOM   2845  C  C   . ASN B 1 63  ? -40.135 14.316  -52.195 1.00 40.79  ? 63  ASN B C   1 
ATOM   2846  O  O   . ASN B 1 63  ? -39.585 14.685  -51.150 1.00 38.74  ? 63  ASN B O   1 
ATOM   2847  C  CB  . ASN B 1 63  ? -38.618 13.769  -54.131 1.00 36.72  ? 63  ASN B CB  1 
ATOM   2848  C  CG  . ASN B 1 63  ? -37.722 12.706  -54.763 1.00 41.03  ? 63  ASN B CG  1 
ATOM   2849  O  OD1 . ASN B 1 63  ? -37.433 11.673  -54.151 1.00 37.71  ? 63  ASN B OD1 1 
ATOM   2850  N  ND2 . ASN B 1 63  ? -37.250 12.973  -55.974 1.00 35.43  ? 63  ASN B ND2 1 
ATOM   2851  N  N   . HIS B 1 64  ? -41.261 14.892  -52.643 1.00 39.94  ? 64  HIS B N   1 
ATOM   2852  C  CA  . HIS B 1 64  ? -41.858 16.010  -51.911 1.00 43.13  ? 64  HIS B CA  1 
ATOM   2853  C  C   . HIS B 1 64  ? -42.612 15.579  -50.655 1.00 41.17  ? 64  HIS B C   1 
ATOM   2854  O  O   . HIS B 1 64  ? -43.033 16.446  -49.878 1.00 39.74  ? 64  HIS B O   1 
ATOM   2855  C  CB  . HIS B 1 64  ? -42.804 16.830  -52.810 1.00 44.73  ? 64  HIS B CB  1 
ATOM   2856  C  CG  . HIS B 1 64  ? -44.119 16.162  -53.091 1.00 45.60  ? 64  HIS B CG  1 
ATOM   2857  N  ND1 . HIS B 1 64  ? -44.330 15.361  -54.195 1.00 48.42  ? 64  HIS B ND1 1 
ATOM   2858  C  CD2 . HIS B 1 64  ? -45.288 16.169  -52.404 1.00 43.07  ? 64  HIS B CD2 1 
ATOM   2859  C  CE1 . HIS B 1 64  ? -45.572 14.905  -54.175 1.00 43.91  ? 64  HIS B CE1 1 
ATOM   2860  N  NE2 . HIS B 1 64  ? -46.172 15.375  -53.095 1.00 42.34  ? 64  HIS B NE2 1 
ATOM   2861  N  N   . ASN B 1 65  ? -42.771 14.280  -50.417 1.00 37.39  ? 65  ASN B N   1 
ATOM   2862  C  CA  . ASN B 1 65  ? -43.406 13.831  -49.185 1.00 41.19  ? 65  ASN B CA  1 
ATOM   2863  C  C   . ASN B 1 65  ? -42.462 13.858  -47.990 1.00 35.11  ? 65  ASN B C   1 
ATOM   2864  O  O   . ASN B 1 65  ? -42.934 13.838  -46.849 1.00 35.50  ? 65  ASN B O   1 
ATOM   2865  C  CB  . ASN B 1 65  ? -43.953 12.405  -49.363 1.00 43.10  ? 65  ASN B CB  1 
ATOM   2866  C  CG  . ASN B 1 65  ? -45.020 12.319  -50.439 1.00 46.24  ? 65  ASN B CG  1 
ATOM   2867  O  OD1 . ASN B 1 65  ? -45.043 11.384  -51.239 1.00 45.07  ? 65  ASN B OD1 1 
ATOM   2868  N  ND2 . ASN B 1 65  ? -45.900 13.316  -50.475 1.00 50.60  ? 65  ASN B ND2 1 
ATOM   2869  N  N   . PHE B 1 66  ? -41.156 13.946  -48.224 1.00 34.23  ? 66  PHE B N   1 
ATOM   2870  C  CA  . PHE B 1 66  ? -40.151 13.992  -47.168 1.00 31.59  ? 66  PHE B CA  1 
ATOM   2871  C  C   . PHE B 1 66  ? -39.785 15.449  -46.926 1.00 33.24  ? 66  PHE B C   1 
ATOM   2872  O  O   . PHE B 1 66  ? -39.188 16.097  -47.790 1.00 36.75  ? 66  PHE B O   1 
ATOM   2873  C  CB  . PHE B 1 66  ? -38.912 13.179  -47.541 1.00 29.72  ? 66  PHE B CB  1 
ATOM   2874  C  CG  . PHE B 1 66  ? -39.178 11.721  -47.735 1.00 28.14  ? 66  PHE B CG  1 
ATOM   2875  C  CD1 . PHE B 1 66  ? -39.422 10.897  -46.644 1.00 33.10  ? 66  PHE B CD1 1 
ATOM   2876  C  CD2 . PHE B 1 66  ? -39.161 11.159  -49.003 1.00 31.81  ? 66  PHE B CD2 1 
ATOM   2877  C  CE1 . PHE B 1 66  ? -39.685 9.537   -46.820 1.00 32.10  ? 66  PHE B CE1 1 
ATOM   2878  C  CE2 . PHE B 1 66  ? -39.409 9.785   -49.190 1.00 31.57  ? 66  PHE B CE2 1 
ATOM   2879  C  CZ  . PHE B 1 66  ? -39.671 8.978   -48.094 1.00 33.29  ? 66  PHE B CZ  1 
ATOM   2880  N  N   . LEU B 1 67  ? -40.225 15.991  -45.800 1.00 32.33  ? 67  LEU B N   1 
ATOM   2881  C  CA  . LEU B 1 67  ? -39.875 17.354  -45.411 1.00 34.07  ? 67  LEU B CA  1 
ATOM   2882  C  C   . LEU B 1 67  ? -38.576 17.328  -44.617 1.00 34.93  ? 67  LEU B C   1 
ATOM   2883  O  O   . LEU B 1 67  ? -38.524 16.733  -43.530 1.00 34.55  ? 67  LEU B O   1 
ATOM   2884  C  CB  . LEU B 1 67  ? -40.982 18.006  -44.584 1.00 31.30  ? 67  LEU B CB  1 
ATOM   2885  C  CG  . LEU B 1 67  ? -42.430 17.862  -45.035 1.00 40.45  ? 67  LEU B CG  1 
ATOM   2886  C  CD1 . LEU B 1 67  ? -43.373 18.388  -43.960 1.00 45.64  ? 67  LEU B CD1 1 
ATOM   2887  C  CD2 . LEU B 1 67  ? -42.646 18.616  -46.352 1.00 49.47  ? 67  LEU B CD2 1 
ATOM   2888  N  N   . VAL B 1 68  ? -37.533 17.959  -45.153 1.00 26.69  ? 68  VAL B N   1 
ATOM   2889  C  CA  . VAL B 1 68  ? -36.245 18.062  -44.477 1.00 27.56  ? 68  VAL B CA  1 
ATOM   2890  C  C   . VAL B 1 68  ? -36.040 19.512  -44.074 1.00 32.34  ? 68  VAL B C   1 
ATOM   2891  O  O   . VAL B 1 68  ? -36.206 20.424  -44.893 1.00 33.99  ? 68  VAL B O   1 
ATOM   2892  C  CB  . VAL B 1 68  ? -35.090 17.582  -45.367 1.00 27.40  ? 68  VAL B CB  1 
ATOM   2893  C  CG1 . VAL B 1 68  ? -33.759 17.787  -44.664 1.00 21.84  ? 68  VAL B CG1 1 
ATOM   2894  C  CG2 . VAL B 1 68  ? -35.287 16.120  -45.737 1.00 28.78  ? 68  VAL B CG2 1 
ATOM   2895  N  N   . GLN B 1 69  ? -35.649 19.731  -42.828 1.00 27.22  ? 69  GLN B N   1 
ATOM   2896  C  CA  . GLN B 1 69  ? -35.542 21.087  -42.307 1.00 34.27  ? 69  GLN B CA  1 
ATOM   2897  C  C   . GLN B 1 69  ? -34.227 21.238  -41.567 1.00 27.96  ? 69  GLN B C   1 
ATOM   2898  O  O   . GLN B 1 69  ? -34.010 20.586  -40.546 1.00 26.04  ? 69  GLN B O   1 
ATOM   2899  C  CB  . GLN B 1 69  ? -36.707 21.417  -41.385 1.00 35.05  ? 69  GLN B CB  1 
ATOM   2900  C  CG  . GLN B 1 69  ? -36.770 22.877  -41.053 1.00 39.75  ? 69  GLN B CG  1 
ATOM   2901  C  CD  . GLN B 1 69  ? -38.026 23.243  -40.307 1.00 43.99  ? 69  GLN B CD  1 
ATOM   2902  O  OE1 . GLN B 1 69  ? -39.088 22.659  -40.521 1.00 45.66  ? 69  GLN B OE1 1 
ATOM   2903  N  NE2 . GLN B 1 69  ? -37.914 24.220  -39.422 1.00 46.59  ? 69  GLN B NE2 1 
ATOM   2904  N  N   . ALA B 1 70  ? -33.351 22.083  -42.090 1.00 26.65  ? 70  ALA B N   1 
ATOM   2905  C  CA  . ALA B 1 70  ? -32.115 22.439  -41.411 1.00 30.29  ? 70  ALA B CA  1 
ATOM   2906  C  C   . ALA B 1 70  ? -32.355 23.741  -40.654 1.00 30.24  ? 70  ALA B C   1 
ATOM   2907  O  O   . ALA B 1 70  ? -32.441 24.808  -41.257 1.00 29.44  ? 70  ALA B O   1 
ATOM   2908  C  CB  . ALA B 1 70  ? -30.967 22.578  -42.404 1.00 30.29  ? 70  ALA B CB  1 
ATOM   2909  N  N   . GLY B 1 71  ? -32.459 23.659  -39.339 1.00 38.43  ? 71  GLY B N   1 
ATOM   2910  C  CA  . GLY B 1 71  ? -32.873 24.826  -38.592 1.00 38.52  ? 71  GLY B CA  1 
ATOM   2911  C  C   . GLY B 1 71  ? -34.235 25.285  -39.054 1.00 35.81  ? 71  GLY B C   1 
ATOM   2912  O  O   . GLY B 1 71  ? -35.239 24.594  -38.875 1.00 31.84  ? 71  GLY B O   1 
ATOM   2913  N  N   . ASN B 1 72  ? -34.272 26.455  -39.674 1.00 39.73  ? 72  ASN B N   1 
ATOM   2914  C  CA  . ASN B 1 72  ? -35.516 27.037  -40.146 1.00 40.16  ? 72  ASN B CA  1 
ATOM   2915  C  C   . ASN B 1 72  ? -35.681 26.922  -41.656 1.00 40.11  ? 72  ASN B C   1 
ATOM   2916  O  O   . ASN B 1 72  ? -36.769 27.218  -42.162 1.00 40.62  ? 72  ASN B O   1 
ATOM   2917  C  CB  . ASN B 1 72  ? -35.551 28.516  -39.725 1.00 45.80  ? 72  ASN B CB  1 
ATOM   2918  C  CG  . ASN B 1 72  ? -36.946 29.032  -39.457 1.00 48.35  ? 72  ASN B CG  1 
ATOM   2919  O  OD1 . ASN B 1 72  ? -37.597 28.630  -38.489 1.00 50.58  ? 72  ASN B OD1 1 
ATOM   2920  N  ND2 . ASN B 1 72  ? -37.394 29.972  -40.281 1.00 48.92  ? 72  ASN B ND2 1 
ATOM   2921  N  N   . VAL B 1 73  ? -34.662 26.433  -42.377 1.00 34.29  ? 73  VAL B N   1 
ATOM   2922  C  CA  . VAL B 1 73  ? -34.666 26.433  -43.836 1.00 33.05  ? 73  VAL B CA  1 
ATOM   2923  C  C   . VAL B 1 73  ? -35.120 25.076  -44.337 1.00 35.40  ? 73  VAL B C   1 
ATOM   2924  O  O   . VAL B 1 73  ? -34.718 24.033  -43.807 1.00 35.91  ? 73  VAL B O   1 
ATOM   2925  C  CB  . VAL B 1 73  ? -33.291 26.795  -44.440 1.00 36.08  ? 73  VAL B CB  1 
ATOM   2926  C  CG1 . VAL B 1 73  ? -32.202 25.852  -43.985 1.00 37.74  ? 73  VAL B CG1 1 
ATOM   2927  C  CG2 . VAL B 1 73  ? -33.358 26.777  -45.965 1.00 35.71  ? 73  VAL B CG2 1 
ATOM   2928  N  N   . GLN B 1 74  ? -36.001 25.106  -45.329 1.00 36.95  ? 74  GLN B N   1 
ATOM   2929  C  CA  . GLN B 1 74  ? -36.479 23.923  -46.014 1.00 30.43  ? 74  GLN B CA  1 
ATOM   2930  C  C   . GLN B 1 74  ? -35.469 23.457  -47.054 1.00 35.31  ? 74  GLN B C   1 
ATOM   2931  O  O   . GLN B 1 74  ? -35.124 24.212  -47.967 1.00 36.72  ? 74  GLN B O   1 
ATOM   2932  C  CB  . GLN B 1 74  ? -37.810 24.254  -46.679 1.00 37.72  ? 74  GLN B CB  1 
ATOM   2933  C  CG  . GLN B 1 74  ? -38.434 23.056  -47.308 1.00 45.79  ? 74  GLN B CG  1 
ATOM   2934  C  CD  . GLN B 1 74  ? -38.812 22.023  -46.276 1.00 50.06  ? 74  GLN B CD  1 
ATOM   2935  O  OE1 . GLN B 1 74  ? -39.171 22.347  -45.127 1.00 42.05  ? 74  GLN B OE1 1 
ATOM   2936  N  NE2 . GLN B 1 74  ? -38.643 20.760  -46.646 1.00 44.30  ? 74  GLN B NE2 1 
ATOM   2937  N  N   . LEU B 1 75  ? -35.045 22.199  -46.960 1.00 35.37  ? 75  LEU B N   1 
ATOM   2938  C  CA  . LEU B 1 75  ? -34.215 21.617  -48.005 1.00 35.81  ? 75  LEU B CA  1 
ATOM   2939  C  C   . LEU B 1 75  ? -35.103 20.911  -49.013 1.00 34.44  ? 75  LEU B C   1 
ATOM   2940  O  O   . LEU B 1 75  ? -36.225 20.500  -48.708 1.00 46.49  ? 75  LEU B O   1 
ATOM   2941  C  CB  . LEU B 1 75  ? -33.189 20.624  -47.461 1.00 32.08  ? 75  LEU B CB  1 
ATOM   2942  C  CG  . LEU B 1 75  ? -32.286 21.073  -46.329 1.00 31.08  ? 75  LEU B CG  1 
ATOM   2943  C  CD1 . LEU B 1 75  ? -31.235 20.030  -46.143 1.00 28.77  ? 75  LEU B CD1 1 
ATOM   2944  C  CD2 . LEU B 1 75  ? -31.673 22.427  -46.633 1.00 33.83  ? 75  LEU B CD2 1 
ATOM   2945  N  N   . ARG B 1 76  ? -34.587 20.754  -50.219 1.00 32.92  ? 76  ARG B N   1 
ATOM   2946  C  CA  . ARG B 1 76  ? -35.390 20.266  -51.326 1.00 35.60  ? 76  ARG B CA  1 
ATOM   2947  C  C   . ARG B 1 76  ? -34.940 18.845  -51.636 1.00 32.99  ? 76  ARG B C   1 
ATOM   2948  O  O   . ARG B 1 76  ? -33.780 18.621  -51.988 1.00 34.58  ? 76  ARG B O   1 
ATOM   2949  C  CB  . ARG B 1 76  ? -35.233 21.201  -52.528 1.00 37.95  ? 76  ARG B CB  1 
ATOM   2950  C  CG  . ARG B 1 76  ? -36.226 21.013  -53.654 1.00 44.52  ? 76  ARG B CG  1 
ATOM   2951  C  CD  . ARG B 1 76  ? -37.191 22.224  -53.690 1.00 50.97  ? 76  ARG B CD  1 
ATOM   2952  N  NE  . ARG B 1 76  ? -37.944 22.379  -52.446 1.00 49.19  ? 76  ARG B NE  1 
ATOM   2953  C  CZ  . ARG B 1 76  ? -38.653 23.453  -52.113 1.00 52.80  ? 76  ARG B CZ  1 
ATOM   2954  N  NH1 . ARG B 1 76  ? -38.728 24.511  -52.910 1.00 54.32  ? 76  ARG B NH1 1 
ATOM   2955  N  NH2 . ARG B 1 76  ? -39.292 23.472  -50.944 1.00 41.27  ? 76  ARG B NH2 1 
ATOM   2956  N  N   . VAL B 1 77  ? -35.849 17.890  -51.503 1.00 33.25  ? 77  VAL B N   1 
ATOM   2957  C  CA  . VAL B 1 77  ? -35.523 16.481  -51.697 1.00 33.05  ? 77  VAL B CA  1 
ATOM   2958  C  C   . VAL B 1 77  ? -35.679 16.152  -53.177 1.00 35.14  ? 77  VAL B C   1 
ATOM   2959  O  O   . VAL B 1 77  ? -36.750 16.366  -53.761 1.00 33.16  ? 77  VAL B O   1 
ATOM   2960  C  CB  . VAL B 1 77  ? -36.402 15.577  -50.822 1.00 33.54  ? 77  VAL B CB  1 
ATOM   2961  C  CG1 . VAL B 1 77  ? -36.137 14.123  -51.154 1.00 28.14  ? 77  VAL B CG1 1 
ATOM   2962  C  CG2 . VAL B 1 77  ? -36.105 15.846  -49.358 1.00 26.04  ? 77  VAL B CG2 1 
ATOM   2963  N  N   . ILE B 1 78  ? -34.590 15.685  -53.791 1.00 32.30  ? 78  ILE B N   1 
ATOM   2964  C  CA  . ILE B 1 78  ? -34.538 15.388  -55.217 1.00 30.26  ? 78  ILE B CA  1 
ATOM   2965  C  C   . ILE B 1 78  ? -34.324 13.912  -55.505 1.00 36.98  ? 78  ILE B C   1 
ATOM   2966  O  O   . ILE B 1 78  ? -34.317 13.518  -56.675 1.00 34.98  ? 78  ILE B O   1 
ATOM   2967  C  CB  . ILE B 1 78  ? -33.458 16.238  -55.919 1.00 27.94  ? 78  ILE B CB  1 
ATOM   2968  C  CG1 . ILE B 1 78  ? -32.078 15.937  -55.336 1.00 29.38  ? 78  ILE B CG1 1 
ATOM   2969  C  CG2 . ILE B 1 78  ? -33.785 17.720  -55.777 1.00 27.69  ? 78  ILE B CG2 1 
ATOM   2970  C  CD1 . ILE B 1 78  ? -30.942 16.710  -55.981 1.00 27.98  ? 78  ILE B CD1 1 
ATOM   2971  N  N   . GLY B 1 79  ? -34.178 13.084  -54.476 1.00 34.16  ? 79  GLY B N   1 
ATOM   2972  C  CA  . GLY B 1 79  ? -34.099 11.648  -54.646 1.00 31.11  ? 79  GLY B CA  1 
ATOM   2973  C  C   . GLY B 1 79  ? -34.123 10.941  -53.306 1.00 32.08  ? 79  GLY B C   1 
ATOM   2974  O  O   . GLY B 1 79  ? -33.849 11.537  -52.257 1.00 28.36  ? 79  GLY B O   1 
ATOM   2975  N  N   . HIS B 1 80  ? -34.455 9.653   -53.354 1.00 29.61  ? 80  HIS B N   1 
ATOM   2976  C  CA  . HIS B 1 80  ? -34.448 8.863   -52.137 1.00 31.08  ? 80  HIS B CA  1 
ATOM   2977  C  C   . HIS B 1 80  ? -34.170 7.410   -52.471 1.00 27.45  ? 80  HIS B C   1 
ATOM   2978  O  O   . HIS B 1 80  ? -34.475 6.940   -53.565 1.00 26.26  ? 80  HIS B O   1 
ATOM   2979  C  CB  . HIS B 1 80  ? -35.769 9.002   -51.373 1.00 31.15  ? 80  HIS B CB  1 
ATOM   2980  C  CG  . HIS B 1 80  ? -36.939 8.404   -52.080 1.00 35.22  ? 80  HIS B CG  1 
ATOM   2981  N  ND1 . HIS B 1 80  ? -37.702 9.114   -52.980 1.00 38.23  ? 80  HIS B ND1 1 
ATOM   2982  C  CD2 . HIS B 1 80  ? -37.480 7.160   -52.021 1.00 41.60  ? 80  HIS B CD2 1 
ATOM   2983  C  CE1 . HIS B 1 80  ? -38.661 8.334   -53.449 1.00 39.15  ? 80  HIS B CE1 1 
ATOM   2984  N  NE2 . HIS B 1 80  ? -38.551 7.145   -52.880 1.00 38.21  ? 80  HIS B NE2 1 
ATOM   2985  N  N   . SER B 1 81  ? -33.560 6.712   -51.520 1.00 24.79  ? 81  SER B N   1 
ATOM   2986  C  CA  . SER B 1 81  ? -33.385 5.272   -51.631 1.00 30.50  ? 81  SER B CA  1 
ATOM   2987  C  C   . SER B 1 81  ? -33.241 4.722   -50.220 1.00 30.92  ? 81  SER B C   1 
ATOM   2988  O  O   . SER B 1 81  ? -32.980 5.472   -49.270 1.00 28.04  ? 81  SER B O   1 
ATOM   2989  C  CB  . SER B 1 81  ? -32.188 4.892   -52.518 1.00 28.74  ? 81  SER B CB  1 
ATOM   2990  O  OG  . SER B 1 81  ? -30.956 5.427   -52.078 1.00 25.46  ? 81  SER B OG  1 
ATOM   2991  N  N   . MET B 1 82  ? -33.414 3.404   -50.096 1.00 29.89  ? 82  MET B N   1 
ATOM   2992  C  CA  . MET B 1 82  ? -33.387 2.703   -48.814 1.00 25.02  ? 82  MET B CA  1 
ATOM   2993  C  C   . MET B 1 82  ? -32.196 1.758   -48.738 1.00 25.25  ? 82  MET B C   1 
ATOM   2994  O  O   . MET B 1 82  ? -31.988 0.939   -49.636 1.00 29.76  ? 82  MET B O   1 
ATOM   2995  C  CB  . MET B 1 82  ? -34.677 1.913   -48.614 1.00 29.08  ? 82  MET B CB  1 
ATOM   2996  C  CG  . MET B 1 82  ? -34.723 1.130   -47.311 1.00 28.88  ? 82  MET B CG  1 
ATOM   2997  S  SD  . MET B 1 82  ? -36.392 0.602   -46.888 1.00 36.95  ? 82  MET B SD  1 
ATOM   2998  C  CE  . MET B 1 82  ? -36.721 -0.503  -48.227 1.00 32.53  ? 82  MET B CE  1 
ATOM   2999  N  N   . GLN B 1 83  ? -31.458 1.814   -47.636 1.00 22.50  ? 83  GLN B N   1 
ATOM   3000  C  CA  . GLN B 1 83  ? -30.352 0.888   -47.410 1.00 21.82  ? 83  GLN B CA  1 
ATOM   3001  C  C   . GLN B 1 83  ? -30.567 0.212   -46.073 1.00 22.56  ? 83  GLN B C   1 
ATOM   3002  O  O   . GLN B 1 83  ? -30.405 0.848   -45.024 1.00 21.74  ? 83  GLN B O   1 
ATOM   3003  C  CB  . GLN B 1 83  ? -28.999 1.591   -47.441 1.00 26.25  ? 83  GLN B CB  1 
ATOM   3004  C  CG  . GLN B 1 83  ? -27.852 0.681   -47.043 1.00 25.15  ? 83  GLN B CG  1 
ATOM   3005  C  CD  . GLN B 1 83  ? -26.495 1.298   -47.362 1.00 37.92  ? 83  GLN B CD  1 
ATOM   3006  O  OE1 . GLN B 1 83  ? -26.357 2.538   -47.434 1.00 31.57  ? 83  GLN B OE1 1 
ATOM   3007  N  NE2 . GLN B 1 83  ? -25.491 0.438   -47.598 1.00 33.88  ? 83  GLN B NE2 1 
ATOM   3008  N  N   . ASN B 1 84  ? -30.938 -1.075  -46.122 1.00 20.39  ? 84  ASN B N   1 
ATOM   3009  C  CA  . ASN B 1 84  ? -31.323 -1.800  -44.917 1.00 18.13  ? 84  ASN B CA  1 
ATOM   3010  C  C   . ASN B 1 84  ? -32.330 -0.966  -44.138 1.00 20.06  ? 84  ASN B C   1 
ATOM   3011  O  O   . ASN B 1 84  ? -33.405 -0.660  -44.657 1.00 20.51  ? 84  ASN B O   1 
ATOM   3012  C  CB  . ASN B 1 84  ? -30.089 -2.150  -44.100 1.00 17.19  ? 84  ASN B CB  1 
ATOM   3013  C  CG  . ASN B 1 84  ? -29.104 -2.974  -44.905 1.00 23.85  ? 84  ASN B CG  1 
ATOM   3014  O  OD1 . ASN B 1 84  ? -27.939 -2.591  -45.066 1.00 28.22  ? 84  ASN B OD1 1 
ATOM   3015  N  ND2 . ASN B 1 84  ? -29.579 -4.088  -45.463 1.00 17.59  ? 84  ASN B ND2 1 
ATOM   3016  N  N   . CYS B 1 85  ? -31.984 -0.536  -42.930 1.00 19.91  ? 85  CYS B N   1 
ATOM   3017  C  CA  . CYS B 1 85  ? -32.927 0.184   -42.089 1.00 22.76  ? 85  CYS B CA  1 
ATOM   3018  C  C   . CYS B 1 85  ? -32.745 1.706   -42.119 1.00 23.83  ? 85  CYS B C   1 
ATOM   3019  O  O   . CYS B 1 85  ? -33.356 2.402   -41.297 1.00 24.59  ? 85  CYS B O   1 
ATOM   3020  C  CB  . CYS B 1 85  ? -32.854 -0.344  -40.650 1.00 20.05  ? 85  CYS B CB  1 
ATOM   3021  S  SG  . CYS B 1 85  ? -33.358 -2.139  -40.484 1.00 22.86  ? 85  CYS B SG  1 
ATOM   3022  N  N   . VAL B 1 86  ? -31.923 2.260   -43.011 1.00 16.45  ? 86  VAL B N   1 
ATOM   3023  C  CA  . VAL B 1 86  ? -31.854 3.720   -43.075 1.00 24.16  ? 86  VAL B CA  1 
ATOM   3024  C  C   . VAL B 1 86  ? -32.430 4.223   -44.396 1.00 23.68  ? 86  VAL B C   1 
ATOM   3025  O  O   . VAL B 1 86  ? -32.356 3.570   -45.437 1.00 25.92  ? 86  VAL B O   1 
ATOM   3026  C  CB  . VAL B 1 86  ? -30.439 4.317   -42.845 1.00 26.03  ? 86  VAL B CB  1 
ATOM   3027  C  CG1 . VAL B 1 86  ? -29.963 4.058   -41.420 1.00 24.86  ? 86  VAL B CG1 1 
ATOM   3028  C  CG2 . VAL B 1 86  ? -29.439 3.813   -43.861 1.00 28.80  ? 86  VAL B CG2 1 
ATOM   3029  N  N   . LEU B 1 87  ? -33.024 5.402   -44.335 1.00 23.53  ? 87  LEU B N   1 
ATOM   3030  C  CA  . LEU B 1 87  ? -33.454 6.122   -45.523 1.00 25.25  ? 87  LEU B CA  1 
ATOM   3031  C  C   . LEU B 1 87  ? -32.344 7.091   -45.936 1.00 26.99  ? 87  LEU B C   1 
ATOM   3032  O  O   . LEU B 1 87  ? -31.655 7.664   -45.083 1.00 25.44  ? 87  LEU B O   1 
ATOM   3033  C  CB  . LEU B 1 87  ? -34.752 6.876   -45.232 1.00 24.11  ? 87  LEU B CB  1 
ATOM   3034  C  CG  . LEU B 1 87  ? -35.703 7.242   -46.369 1.00 30.20  ? 87  LEU B CG  1 
ATOM   3035  C  CD1 . LEU B 1 87  ? -36.315 6.009   -47.009 1.00 26.96  ? 87  LEU B CD1 1 
ATOM   3036  C  CD2 . LEU B 1 87  ? -36.787 8.140   -45.829 1.00 29.27  ? 87  LEU B CD2 1 
ATOM   3037  N  N   . LYS B 1 88  ? -32.129 7.234   -47.241 1.00 23.85  ? 88  LYS B N   1 
ATOM   3038  C  CA  . LYS B 1 88  ? -31.139 8.177   -47.758 1.00 23.61  ? 88  LYS B CA  1 
ATOM   3039  C  C   . LYS B 1 88  ? -31.839 9.169   -48.675 1.00 24.59  ? 88  LYS B C   1 
ATOM   3040  O  O   . LYS B 1 88  ? -32.315 8.796   -49.753 1.00 29.20  ? 88  LYS B O   1 
ATOM   3041  C  CB  . LYS B 1 88  ? -30.007 7.461   -48.491 1.00 25.30  ? 88  LYS B CB  1 
ATOM   3042  C  CG  . LYS B 1 88  ? -29.249 6.509   -47.591 1.00 27.09  ? 88  LYS B CG  1 
ATOM   3043  C  CD  . LYS B 1 88  ? -27.862 6.222   -48.111 1.00 28.23  ? 88  LYS B CD  1 
ATOM   3044  C  CE  . LYS B 1 88  ? -27.865 5.207   -49.214 1.00 22.95  ? 88  LYS B CE  1 
ATOM   3045  N  NZ  . LYS B 1 88  ? -26.471 4.702   -49.447 1.00 23.89  ? 88  LYS B NZ  1 
ATOM   3046  N  N   . LEU B 1 89  ? -31.893 10.424  -48.256 1.00 23.13  ? 89  LEU B N   1 
ATOM   3047  C  CA  . LEU B 1 89  ? -32.556 11.468  -49.017 1.00 26.58  ? 89  LEU B CA  1 
ATOM   3048  C  C   . LEU B 1 89  ? -31.492 12.330  -49.703 1.00 29.97  ? 89  LEU B C   1 
ATOM   3049  O  O   . LEU B 1 89  ? -30.734 13.067  -49.045 1.00 22.88  ? 89  LEU B O   1 
ATOM   3050  C  CB  . LEU B 1 89  ? -33.463 12.307  -48.119 1.00 24.69  ? 89  LEU B CB  1 
ATOM   3051  C  CG  . LEU B 1 89  ? -34.529 11.600  -47.283 1.00 27.14  ? 89  LEU B CG  1 
ATOM   3052  C  CD1 . LEU B 1 89  ? -35.269 12.636  -46.477 1.00 24.61  ? 89  LEU B CD1 1 
ATOM   3053  C  CD2 . LEU B 1 89  ? -35.506 10.844  -48.162 1.00 25.87  ? 89  LEU B CD2 1 
ATOM   3054  N  N   . LYS B 1 90  ? -31.434 12.238  -51.026 1.00 25.23  ? 90  LYS B N   1 
ATOM   3055  C  CA  . LYS B 1 90  ? -30.577 13.150  -51.753 1.00 28.84  ? 90  LYS B CA  1 
ATOM   3056  C  C   . LYS B 1 90  ? -31.276 14.497  -51.780 1.00 29.28  ? 90  LYS B C   1 
ATOM   3057  O  O   . LYS B 1 90  ? -32.451 14.594  -52.149 1.00 28.58  ? 90  LYS B O   1 
ATOM   3058  C  CB  . LYS B 1 90  ? -30.299 12.658  -53.173 1.00 28.83  ? 90  LYS B CB  1 
ATOM   3059  C  CG  . LYS B 1 90  ? -29.261 13.514  -53.870 1.00 36.58  ? 90  LYS B CG  1 
ATOM   3060  C  CD  . LYS B 1 90  ? -28.721 12.889  -55.132 1.00 39.95  ? 90  LYS B CD  1 
ATOM   3061  C  CE  . LYS B 1 90  ? -27.592 13.743  -55.721 1.00 47.22  ? 90  LYS B CE  1 
ATOM   3062  N  NZ  . LYS B 1 90  ? -28.039 14.968  -56.467 1.00 49.99  ? 90  LYS B NZ  1 
ATOM   3063  N  N   . VAL B 1 91  ? -30.578 15.525  -51.329 1.00 29.51  ? 91  VAL B N   1 
ATOM   3064  C  CA  . VAL B 1 91  ? -31.101 16.876  -51.374 1.00 27.21  ? 91  VAL B CA  1 
ATOM   3065  C  C   . VAL B 1 91  ? -30.225 17.650  -52.342 1.00 30.83  ? 91  VAL B C   1 
ATOM   3066  O  O   . VAL B 1 91  ? -29.118 17.233  -52.685 1.00 28.52  ? 91  VAL B O   1 
ATOM   3067  C  CB  . VAL B 1 91  ? -31.129 17.542  -49.993 1.00 25.47  ? 91  VAL B CB  1 
ATOM   3068  C  CG1 . VAL B 1 91  ? -32.115 16.841  -49.099 1.00 28.96  ? 91  VAL B CG1 1 
ATOM   3069  C  CG2 . VAL B 1 91  ? -29.768 17.485  -49.395 1.00 27.71  ? 91  VAL B CG2 1 
ATOM   3070  N  N   . ASP B 1 92  ? -30.733 18.791  -52.794 1.00 31.04  ? 92  ASP B N   1 
ATOM   3071  C  CA  . ASP B 1 92  ? -30.063 19.567  -53.826 1.00 22.78  ? 92  ASP B CA  1 
ATOM   3072  C  C   . ASP B 1 92  ? -28.951 20.461  -53.292 1.00 30.37  ? 92  ASP B C   1 
ATOM   3073  O  O   . ASP B 1 92  ? -28.295 21.145  -54.089 1.00 31.48  ? 92  ASP B O   1 
ATOM   3074  C  CB  . ASP B 1 92  ? -31.113 20.375  -54.581 1.00 32.39  ? 92  ASP B CB  1 
ATOM   3075  C  CG  . ASP B 1 92  ? -31.842 21.379  -53.689 1.00 43.34  ? 92  ASP B CG  1 
ATOM   3076  O  OD1 . ASP B 1 92  ? -31.609 21.408  -52.447 1.00 43.60  ? 92  ASP B OD1 1 
ATOM   3077  O  OD2 . ASP B 1 92  ? -32.702 22.112  -54.237 1.00 47.66  ? 92  ASP B OD2 1 
ATOM   3078  N  N   . THR B 1 93  ? -28.709 20.463  -51.979 1.00 31.44  ? 93  THR B N   1 
ATOM   3079  C  CA  . THR B 1 93  ? -27.712 21.331  -51.357 1.00 33.04  ? 93  THR B CA  1 
ATOM   3080  C  C   . THR B 1 93  ? -26.745 20.479  -50.544 1.00 32.18  ? 93  THR B C   1 
ATOM   3081  O  O   . THR B 1 93  ? -27.166 19.777  -49.619 1.00 28.80  ? 93  THR B O   1 
ATOM   3082  C  CB  . THR B 1 93  ? -28.381 22.362  -50.438 1.00 32.18  ? 93  THR B CB  1 
ATOM   3083  O  OG1 . THR B 1 93  ? -29.406 23.068  -51.155 1.00 31.68  ? 93  THR B OG1 1 
ATOM   3084  C  CG2 . THR B 1 93  ? -27.345 23.359  -49.931 1.00 28.13  ? 93  THR B CG2 1 
ATOM   3085  N  N   . ALA B 1 94  ? -25.451 20.597  -50.836 1.00 29.61  ? 94  ALA B N   1 
ATOM   3086  C  CA  . ALA B 1 94  ? -24.437 19.977  -49.995 1.00 24.74  ? 94  ALA B CA  1 
ATOM   3087  C  C   . ALA B 1 94  ? -24.316 20.744  -48.690 1.00 28.44  ? 94  ALA B C   1 
ATOM   3088  O  O   . ALA B 1 94  ? -24.345 21.981  -48.674 1.00 26.79  ? 94  ALA B O   1 
ATOM   3089  C  CB  . ALA B 1 94  ? -23.084 19.948  -50.696 1.00 27.28  ? 94  ALA B CB  1 
ATOM   3090  N  N   . ASN B 1 95  ? -24.211 20.005  -47.590 1.00 28.88  ? 95  ASN B N   1 
ATOM   3091  C  CA  . ASN B 1 95  ? -24.105 20.642  -46.287 1.00 26.45  ? 95  ASN B CA  1 
ATOM   3092  C  C   . ASN B 1 95  ? -22.786 21.396  -46.203 1.00 25.17  ? 95  ASN B C   1 
ATOM   3093  O  O   . ASN B 1 95  ? -21.721 20.765  -46.195 1.00 24.50  ? 95  ASN B O   1 
ATOM   3094  C  CB  . ASN B 1 95  ? -24.242 19.614  -45.152 1.00 26.52  ? 95  ASN B CB  1 
ATOM   3095  C  CG  . ASN B 1 95  ? -24.212 20.263  -43.750 1.00 24.31  ? 95  ASN B CG  1 
ATOM   3096  O  OD1 . ASN B 1 95  ? -24.102 21.476  -43.620 1.00 21.89  ? 95  ASN B OD1 1 
ATOM   3097  N  ND2 . ASN B 1 95  ? -24.363 19.451  -42.717 1.00 19.94  ? 95  ASN B ND2 1 
ATOM   3098  N  N   . PRO B 1 96  ? -22.804 22.727  -46.139 1.00 30.35  ? 96  PRO B N   1 
ATOM   3099  C  CA  . PRO B 1 96  ? -21.541 23.478  -46.041 1.00 28.26  ? 96  PRO B CA  1 
ATOM   3100  C  C   . PRO B 1 96  ? -20.777 23.188  -44.770 1.00 27.89  ? 96  PRO B C   1 
ATOM   3101  O  O   . PRO B 1 96  ? -19.573 23.488  -44.693 1.00 25.82  ? 96  PRO B O   1 
ATOM   3102  C  CB  . PRO B 1 96  ? -21.994 24.941  -46.106 1.00 21.94  ? 96  PRO B CB  1 
ATOM   3103  C  CG  . PRO B 1 96  ? -23.412 24.906  -45.619 1.00 27.74  ? 96  PRO B CG  1 
ATOM   3104  C  CD  . PRO B 1 96  ? -23.988 23.603  -46.069 1.00 26.61  ? 96  PRO B CD  1 
ATOM   3105  N  N   . LYS B 1 97  ? -21.440 22.650  -43.754 1.00 24.63  ? 97  LYS B N   1 
ATOM   3106  C  CA  . LYS B 1 97  ? -20.782 22.336  -42.500 1.00 22.82  ? 97  LYS B CA  1 
ATOM   3107  C  C   . LYS B 1 97  ? -20.341 20.884  -42.407 1.00 22.91  ? 97  LYS B C   1 
ATOM   3108  O  O   . LYS B 1 97  ? -19.858 20.480  -41.351 1.00 24.83  ? 97  LYS B O   1 
ATOM   3109  C  CB  . LYS B 1 97  ? -21.713 22.664  -41.332 1.00 23.33  ? 97  LYS B CB  1 
ATOM   3110  C  CG  . LYS B 1 97  ? -22.045 24.147  -41.180 1.00 26.85  ? 97  LYS B CG  1 
ATOM   3111  C  CD  . LYS B 1 97  ? -22.914 24.373  -39.963 1.00 27.45  ? 97  LYS B CD  1 
ATOM   3112  C  CE  . LYS B 1 97  ? -23.719 25.647  -40.091 1.00 33.92  ? 97  LYS B CE  1 
ATOM   3113  N  NZ  . LYS B 1 97  ? -24.771 25.697  -39.042 1.00 34.79  ? 97  LYS B NZ  1 
ATOM   3114  N  N   . THR B 1 98  ? -20.450 20.106  -43.486 1.00 23.10  ? 98  THR B N   1 
ATOM   3115  C  CA  . THR B 1 98  ? -20.070 18.689  -43.452 1.00 27.26  ? 98  THR B CA  1 
ATOM   3116  C  C   . THR B 1 98  ? -18.617 18.525  -43.021 1.00 26.35  ? 98  THR B C   1 
ATOM   3117  O  O   . THR B 1 98  ? -17.723 19.054  -43.693 1.00 27.91  ? 98  THR B O   1 
ATOM   3118  C  CB  . THR B 1 98  ? -20.245 17.993  -44.817 1.00 29.86  ? 98  THR B CB  1 
ATOM   3119  O  OG1 . THR B 1 98  ? -21.604 18.080  -45.263 1.00 28.92  ? 98  THR B OG1 1 
ATOM   3120  C  CG2 . THR B 1 98  ? -19.844 16.521  -44.710 1.00 26.45  ? 98  THR B CG2 1 
ATOM   3121  N  N   . PRO B 1 99  ? -18.338 17.777  -41.955 1.00 27.70  ? 99  PRO B N   1 
ATOM   3122  C  CA  . PRO B 1 99  ? -16.951 17.496  -41.568 1.00 28.08  ? 99  PRO B CA  1 
ATOM   3123  C  C   . PRO B 1 99  ? -16.370 16.352  -42.387 1.00 22.56  ? 99  PRO B C   1 
ATOM   3124  O  O   . PRO B 1 99  ? -17.061 15.696  -43.154 1.00 24.47  ? 99  PRO B O   1 
ATOM   3125  C  CB  . PRO B 1 99  ? -17.083 17.106  -40.091 1.00 26.08  ? 99  PRO B CB  1 
ATOM   3126  C  CG  . PRO B 1 99  ? -18.424 16.391  -40.046 1.00 25.71  ? 99  PRO B CG  1 
ATOM   3127  C  CD  . PRO B 1 99  ? -19.307 17.102  -41.059 1.00 26.99  ? 99  PRO B CD  1 
ATOM   3128  N  N   . LYS B 1 100 ? -15.059 16.155  -42.246 1.00 32.92  ? 100 LYS B N   1 
ATOM   3129  C  CA  . LYS B 1 100 ? -14.461 14.880  -42.638 1.00 32.22  ? 100 LYS B CA  1 
ATOM   3130  C  C   . LYS B 1 100 ? -15.070 13.765  -41.801 1.00 28.57  ? 100 LYS B C   1 
ATOM   3131  O  O   . LYS B 1 100 ? -15.188 13.884  -40.578 1.00 30.49  ? 100 LYS B O   1 
ATOM   3132  C  CB  . LYS B 1 100 ? -12.931 14.903  -42.487 1.00 29.60  ? 100 LYS B CB  1 
ATOM   3133  C  CG  . LYS B 1 100 ? -12.273 16.160  -43.052 1.00 44.86  ? 100 LYS B CG  1 
ATOM   3134  C  CD  . LYS B 1 100 ? -10.720 16.122  -43.104 1.00 50.03  ? 100 LYS B CD  1 
ATOM   3135  C  CE  . LYS B 1 100 ? -10.174 17.377  -43.860 1.00 61.91  ? 100 LYS B CE  1 
ATOM   3136  N  NZ  . LYS B 1 100 ? -8.687  17.420  -44.164 1.00 56.82  ? 100 LYS B NZ  1 
ATOM   3137  N  N   . TYR B 1 101 ? -15.476 12.687  -42.460 1.00 24.28  ? 101 TYR B N   1 
ATOM   3138  C  CA  . TYR B 1 101 ? -16.265 11.688  -41.767 1.00 24.92  ? 101 TYR B CA  1 
ATOM   3139  C  C   . TYR B 1 101 ? -16.084 10.321  -42.405 1.00 28.42  ? 101 TYR B C   1 
ATOM   3140  O  O   . TYR B 1 101 ? -15.743 10.198  -43.589 1.00 24.25  ? 101 TYR B O   1 
ATOM   3141  C  CB  . TYR B 1 101 ? -17.756 12.069  -41.748 1.00 30.75  ? 101 TYR B CB  1 
ATOM   3142  C  CG  . TYR B 1 101 ? -18.452 11.929  -43.091 1.00 29.93  ? 101 TYR B CG  1 
ATOM   3143  C  CD1 . TYR B 1 101 ? -18.454 12.979  -43.994 1.00 26.40  ? 101 TYR B CD1 1 
ATOM   3144  C  CD2 . TYR B 1 101 ? -19.097 10.750  -43.455 1.00 26.62  ? 101 TYR B CD2 1 
ATOM   3145  C  CE1 . TYR B 1 101 ? -19.073 12.869  -45.218 1.00 26.37  ? 101 TYR B CE1 1 
ATOM   3146  C  CE2 . TYR B 1 101 ? -19.718 10.636  -44.685 1.00 27.46  ? 101 TYR B CE2 1 
ATOM   3147  C  CZ  . TYR B 1 101 ? -19.697 11.707  -45.562 1.00 27.67  ? 101 TYR B CZ  1 
ATOM   3148  O  OH  . TYR B 1 101 ? -20.313 11.630  -46.794 1.00 31.82  ? 101 TYR B OH  1 
ATOM   3149  N  N   . LYS B 1 102 ? -16.344 9.297   -41.585 1.00 22.15  ? 102 LYS B N   1 
ATOM   3150  C  CA  . LYS B 1 102 ? -16.456 7.911   -42.007 1.00 25.27  ? 102 LYS B CA  1 
ATOM   3151  C  C   . LYS B 1 102 ? -17.674 7.310   -41.324 1.00 26.01  ? 102 LYS B C   1 
ATOM   3152  O  O   . LYS B 1 102 ? -18.095 7.773   -40.260 1.00 22.92  ? 102 LYS B O   1 
ATOM   3153  C  CB  . LYS B 1 102 ? -15.237 7.068   -41.608 1.00 24.78  ? 102 LYS B CB  1 
ATOM   3154  C  CG  . LYS B 1 102 ? -13.903 7.544   -42.108 1.00 36.48  ? 102 LYS B CG  1 
ATOM   3155  C  CD  . LYS B 1 102 ? -12.825 7.311   -41.049 1.00 33.84  ? 102 LYS B CD  1 
ATOM   3156  C  CE  . LYS B 1 102 ? -13.143 6.089   -40.227 1.00 40.35  ? 102 LYS B CE  1 
ATOM   3157  N  NZ  . LYS B 1 102 ? -12.311 5.972   -38.997 1.00 55.23  ? 102 LYS B NZ  1 
ATOM   3158  N  N   . PHE B 1 103 ? -18.211 6.256   -41.938 1.00 19.57  ? 103 PHE B N   1 
ATOM   3159  C  CA  . PHE B 1 103 ? -19.192 5.366   -41.321 1.00 22.32  ? 103 PHE B CA  1 
ATOM   3160  C  C   . PHE B 1 103 ? -18.447 4.109   -40.903 1.00 22.18  ? 103 PHE B C   1 
ATOM   3161  O  O   . PHE B 1 103 ? -17.873 3.431   -41.756 1.00 30.60  ? 103 PHE B O   1 
ATOM   3162  C  CB  . PHE B 1 103 ? -20.305 5.003   -42.305 1.00 19.36  ? 103 PHE B CB  1 
ATOM   3163  C  CG  . PHE B 1 103 ? -21.214 6.152   -42.672 1.00 24.35  ? 103 PHE B CG  1 
ATOM   3164  C  CD1 . PHE B 1 103 ? -21.205 7.336   -41.939 1.00 24.52  ? 103 PHE B CD1 1 
ATOM   3165  C  CD2 . PHE B 1 103 ? -22.083 6.041   -43.732 1.00 18.23  ? 103 PHE B CD2 1 
ATOM   3166  C  CE1 . PHE B 1 103 ? -22.048 8.370   -42.255 1.00 18.62  ? 103 PHE B CE1 1 
ATOM   3167  C  CE2 . PHE B 1 103 ? -22.916 7.065   -44.056 1.00 21.21  ? 103 PHE B CE2 1 
ATOM   3168  C  CZ  . PHE B 1 103 ? -22.907 8.233   -43.310 1.00 22.77  ? 103 PHE B CZ  1 
ATOM   3169  N  N   . VAL B 1 104 ? -18.463 3.779   -39.611 1.00 23.30  ? 104 VAL B N   1 
ATOM   3170  C  CA  . VAL B 1 104 ? -17.777 2.586   -39.128 1.00 23.14  ? 104 VAL B CA  1 
ATOM   3171  C  C   . VAL B 1 104 ? -18.733 1.784   -38.270 1.00 27.50  ? 104 VAL B C   1 
ATOM   3172  O  O   . VAL B 1 104 ? -19.718 2.306   -37.739 1.00 26.09  ? 104 VAL B O   1 
ATOM   3173  C  CB  . VAL B 1 104 ? -16.494 2.894   -38.321 1.00 23.42  ? 104 VAL B CB  1 
ATOM   3174  C  CG1 . VAL B 1 104 ? -15.541 3.727   -39.139 1.00 26.48  ? 104 VAL B CG1 1 
ATOM   3175  C  CG2 . VAL B 1 104 ? -16.848 3.594   -37.036 1.00 28.28  ? 104 VAL B CG2 1 
ATOM   3176  N  N   . ARG B 1 105 ? -18.434 0.489   -38.156 1.00 25.63  ? 105 ARG B N   1 
ATOM   3177  C  CA  . ARG B 1 105 ? -19.155 -0.423  -37.278 1.00 20.85  ? 105 ARG B CA  1 
ATOM   3178  C  C   . ARG B 1 105 ? -18.265 -0.776  -36.091 1.00 25.59  ? 105 ARG B C   1 
ATOM   3179  O  O   . ARG B 1 105 ? -17.281 -1.506  -36.242 1.00 28.60  ? 105 ARG B O   1 
ATOM   3180  C  CB  . ARG B 1 105 ? -19.564 -1.684  -38.030 1.00 23.93  ? 105 ARG B CB  1 
ATOM   3181  C  CG  . ARG B 1 105 ? -20.533 -2.546  -37.250 1.00 22.83  ? 105 ARG B CG  1 
ATOM   3182  C  CD  . ARG B 1 105 ? -21.392 -3.345  -38.166 1.00 23.60  ? 105 ARG B CD  1 
ATOM   3183  N  NE  . ARG B 1 105 ? -22.233 -4.279  -37.431 1.00 24.88  ? 105 ARG B NE  1 
ATOM   3184  C  CZ  . ARG B 1 105 ? -23.523 -4.107  -37.193 1.00 24.88  ? 105 ARG B CZ  1 
ATOM   3185  N  NH1 . ARG B 1 105 ? -24.175 -3.048  -37.646 1.00 25.95  ? 105 ARG B NH1 1 
ATOM   3186  N  NH2 . ARG B 1 105 ? -24.186 -5.038  -36.517 1.00 27.44  ? 105 ARG B NH2 1 
ATOM   3187  N  N   . ILE B 1 106 ? -18.650 -0.337  -34.903 1.00 23.77  ? 106 ILE B N   1 
ATOM   3188  C  CA  . ILE B 1 106 ? -17.842 -0.622  -33.731 1.00 24.43  ? 106 ILE B CA  1 
ATOM   3189  C  C   . ILE B 1 106 ? -18.143 -2.032  -33.227 1.00 28.65  ? 106 ILE B C   1 
ATOM   3190  O  O   . ILE B 1 106 ? -19.170 -2.639  -33.543 1.00 21.00  ? 106 ILE B O   1 
ATOM   3191  C  CB  . ILE B 1 106 ? -18.073 0.401   -32.614 1.00 22.49  ? 106 ILE B CB  1 
ATOM   3192  C  CG1 . ILE B 1 106 ? -19.552 0.453   -32.290 1.00 25.55  ? 106 ILE B CG1 1 
ATOM   3193  C  CG2 . ILE B 1 106 ? -17.556 1.745   -33.025 1.00 29.47  ? 106 ILE B CG2 1 
ATOM   3194  C  CD1 . ILE B 1 106 ? -19.818 1.119   -31.005 1.00 34.52  ? 106 ILE B CD1 1 
ATOM   3195  N  N   . GLN B 1 107 ? -17.216 -2.551  -32.422 1.00 27.98  ? 107 GLN B N   1 
ATOM   3196  C  CA  . GLN B 1 107 ? -17.257 -3.841  -31.768 1.00 30.42  ? 107 GLN B CA  1 
ATOM   3197  C  C   . GLN B 1 107 ? -17.766 -3.675  -30.341 1.00 28.35  ? 107 GLN B C   1 
ATOM   3198  O  O   . GLN B 1 107 ? -17.689 -2.581  -29.771 1.00 28.16  ? 107 GLN B O   1 
ATOM   3199  C  CB  . GLN B 1 107 ? -15.868 -4.487  -31.739 1.00 32.29  ? 107 GLN B CB  1 
ATOM   3200  C  CG  . GLN B 1 107 ? -15.292 -4.732  -33.131 1.00 33.92  ? 107 GLN B CG  1 
ATOM   3201  C  CD  . GLN B 1 107 ? -16.213 -5.537  -34.022 1.00 42.00  ? 107 GLN B CD  1 
ATOM   3202  O  OE1 . GLN B 1 107 ? -16.630 -6.650  -33.680 1.00 48.35  ? 107 GLN B OE1 1 
ATOM   3203  N  NE2 . GLN B 1 107 ? -16.559 -4.961  -35.173 1.00 36.91  ? 107 GLN B NE2 1 
ATOM   3204  N  N   . PRO B 1 108 ? -18.366 -4.733  -29.756 1.00 27.40  ? 108 PRO B N   1 
ATOM   3205  C  CA  . PRO B 1 108 ? -18.780 -4.670  -28.365 1.00 21.48  ? 108 PRO B CA  1 
ATOM   3206  C  C   . PRO B 1 108 ? -17.610 -4.282  -27.450 1.00 20.44  ? 108 PRO B C   1 
ATOM   3207  O  O   . PRO B 1 108 ? -16.528 -4.711  -27.682 1.00 19.66  ? 108 PRO B O   1 
ATOM   3208  C  CB  . PRO B 1 108 ? -19.358 -6.071  -28.123 1.00 25.61  ? 108 PRO B CB  1 
ATOM   3209  C  CG  . PRO B 1 108 ? -19.847 -6.497  -29.468 1.00 27.71  ? 108 PRO B CG  1 
ATOM   3210  C  CD  . PRO B 1 108 ? -18.762 -5.999  -30.389 1.00 26.55  ? 108 PRO B CD  1 
ATOM   3211  N  N   . GLY B 1 109 ? -17.885 -3.445  -26.449 1.00 21.57  ? 109 GLY B N   1 
ATOM   3212  C  CA  . GLY B 1 109 ? -16.844 -2.958  -25.584 1.00 17.55  ? 109 GLY B CA  1 
ATOM   3213  C  C   . GLY B 1 109 ? -16.265 -1.625  -25.995 1.00 27.08  ? 109 GLY B C   1 
ATOM   3214  O  O   . GLY B 1 109 ? -15.564 -0.998  -25.190 1.00 27.01  ? 109 GLY B O   1 
ATOM   3215  N  N   . GLN B 1 110 ? -16.522 -1.173  -27.223 1.00 27.12  ? 110 GLN B N   1 
ATOM   3216  C  CA  . GLN B 1 110 ? -16.069 0.136   -27.662 1.00 25.55  ? 110 GLN B CA  1 
ATOM   3217  C  C   . GLN B 1 110 ? -17.036 1.227   -27.200 1.00 29.11  ? 110 GLN B C   1 
ATOM   3218  O  O   . GLN B 1 110 ? -18.235 0.991   -26.986 1.00 25.20  ? 110 GLN B O   1 
ATOM   3219  C  CB  . GLN B 1 110 ? -15.927 0.173   -29.182 1.00 23.37  ? 110 GLN B CB  1 
ATOM   3220  C  CG  . GLN B 1 110 ? -14.799 -0.692  -29.742 1.00 27.83  ? 110 GLN B CG  1 
ATOM   3221  C  CD  . GLN B 1 110 ? -13.468 -0.500  -29.001 1.00 32.87  ? 110 GLN B CD  1 
ATOM   3222  O  OE1 . GLN B 1 110 ? -12.874 0.590   -29.023 1.00 29.54  ? 110 GLN B OE1 1 
ATOM   3223  N  NE2 . GLN B 1 110 ? -12.989 -1.571  -28.345 1.00 29.12  ? 110 GLN B NE2 1 
ATOM   3224  N  N   . THR B 1 111 ? -16.506 2.429   -27.041 1.00 25.71  ? 111 THR B N   1 
ATOM   3225  C  CA  . THR B 1 111 ? -17.323 3.555   -26.633 1.00 25.91  ? 111 THR B CA  1 
ATOM   3226  C  C   . THR B 1 111 ? -17.509 4.552   -27.779 1.00 23.77  ? 111 THR B C   1 
ATOM   3227  O  O   . THR B 1 111 ? -16.844 4.506   -28.824 1.00 20.97  ? 111 THR B O   1 
ATOM   3228  C  CB  . THR B 1 111 ? -16.725 4.245   -25.397 1.00 23.64  ? 111 THR B CB  1 
ATOM   3229  O  OG1 . THR B 1 111 ? -15.360 4.591   -25.645 1.00 23.30  ? 111 THR B OG1 1 
ATOM   3230  C  CG2 . THR B 1 111 ? -16.830 3.332   -24.172 1.00 22.78  ? 111 THR B CG2 1 
ATOM   3231  N  N   . PHE B 1 112 ? -18.466 5.447   -27.563 1.00 23.39  ? 112 PHE B N   1 
ATOM   3232  C  CA  . PHE B 1 112 ? -18.726 6.538   -28.478 1.00 22.63  ? 112 PHE B CA  1 
ATOM   3233  C  C   . PHE B 1 112 ? -19.580 7.554   -27.740 1.00 23.95  ? 112 PHE B C   1 
ATOM   3234  O  O   . PHE B 1 112 ? -20.142 7.260   -26.676 1.00 21.97  ? 112 PHE B O   1 
ATOM   3235  C  CB  . PHE B 1 112 ? -19.398 6.043   -29.754 1.00 19.36  ? 112 PHE B CB  1 
ATOM   3236  C  CG  . PHE B 1 112 ? -20.679 5.302   -29.521 1.00 21.92  ? 112 PHE B CG  1 
ATOM   3237  C  CD1 . PHE B 1 112 ? -20.673 3.939   -29.289 1.00 25.01  ? 112 PHE B CD1 1 
ATOM   3238  C  CD2 . PHE B 1 112 ? -21.898 5.966   -29.570 1.00 20.02  ? 112 PHE B CD2 1 
ATOM   3239  C  CE1 . PHE B 1 112 ? -21.858 3.250   -29.093 1.00 23.33  ? 112 PHE B CE1 1 
ATOM   3240  C  CE2 . PHE B 1 112 ? -23.076 5.298   -29.376 1.00 21.28  ? 112 PHE B CE2 1 
ATOM   3241  C  CZ  . PHE B 1 112 ? -23.065 3.932   -29.142 1.00 22.95  ? 112 PHE B CZ  1 
ATOM   3242  N  N   . SER B 1 113 ? -19.644 8.762   -28.308 1.00 23.24  ? 113 SER B N   1 
ATOM   3243  C  CA  . SER B 1 113 ? -20.464 9.859   -27.803 1.00 21.63  ? 113 SER B CA  1 
ATOM   3244  C  C   . SER B 1 113 ? -21.801 9.887   -28.527 1.00 20.91  ? 113 SER B C   1 
ATOM   3245  O  O   . SER B 1 113 ? -21.892 9.547   -29.708 1.00 19.37  ? 113 SER B O   1 
ATOM   3246  C  CB  . SER B 1 113 ? -19.772 11.214  -27.999 1.00 20.13  ? 113 SER B CB  1 
ATOM   3247  O  OG  . SER B 1 113 ? -18.448 11.220  -27.497 1.00 19.73  ? 113 SER B OG  1 
ATOM   3248  N  N   . VAL B 1 114 ? -22.841 10.294  -27.805 1.00 20.72  ? 114 VAL B N   1 
ATOM   3249  C  CA  . VAL B 1 114 ? -24.183 10.431  -28.352 1.00 17.51  ? 114 VAL B CA  1 
ATOM   3250  C  C   . VAL B 1 114 ? -24.601 11.890  -28.230 1.00 18.97  ? 114 VAL B C   1 
ATOM   3251  O  O   . VAL B 1 114 ? -24.508 12.475  -27.150 1.00 20.62  ? 114 VAL B O   1 
ATOM   3252  C  CB  . VAL B 1 114 ? -25.198 9.511   -27.647 1.00 22.15  ? 114 VAL B CB  1 
ATOM   3253  C  CG1 . VAL B 1 114 ? -26.606 9.792   -28.173 1.00 17.48  ? 114 VAL B CG1 1 
ATOM   3254  C  CG2 . VAL B 1 114 ? -24.825 7.998   -27.842 1.00 17.03  ? 114 VAL B CG2 1 
ATOM   3255  N  N   . LEU B 1 115 ? -25.025 12.482  -29.336 1.00 17.01  ? 115 LEU B N   1 
ATOM   3256  C  CA  . LEU B 1 115 ? -25.668 13.795  -29.329 1.00 19.74  ? 115 LEU B CA  1 
ATOM   3257  C  C   . LEU B 1 115 ? -27.172 13.579  -29.433 1.00 22.14  ? 115 LEU B C   1 
ATOM   3258  O  O   . LEU B 1 115 ? -27.701 13.309  -30.515 1.00 22.66  ? 115 LEU B O   1 
ATOM   3259  C  CB  . LEU B 1 115 ? -25.140 14.669  -30.458 1.00 16.49  ? 115 LEU B CB  1 
ATOM   3260  C  CG  . LEU B 1 115 ? -25.828 16.026  -30.574 1.00 18.77  ? 115 LEU B CG  1 
ATOM   3261  C  CD1 . LEU B 1 115 ? -25.493 16.925  -29.386 1.00 16.10  ? 115 LEU B CD1 1 
ATOM   3262  C  CD2 . LEU B 1 115 ? -25.421 16.656  -31.909 1.00 15.75  ? 115 LEU B CD2 1 
ATOM   3263  N  N   . ALA B 1 116 ? -27.860 13.658  -28.299 1.00 21.09  ? 116 ALA B N   1 
ATOM   3264  C  CA  . ALA B 1 116 ? -29.295 13.422  -28.276 1.00 18.82  ? 116 ALA B CA  1 
ATOM   3265  C  C   . ALA B 1 116 ? -30.013 14.637  -28.843 1.00 21.86  ? 116 ALA B C   1 
ATOM   3266  O  O   . ALA B 1 116 ? -29.841 15.761  -28.356 1.00 20.50  ? 116 ALA B O   1 
ATOM   3267  C  CB  . ALA B 1 116 ? -29.778 13.123  -26.857 1.00 17.48  ? 116 ALA B CB  1 
ATOM   3268  N  N   . CYS B 1 117 ? -30.856 14.395  -29.849 1.00 23.94  ? 117 CYS B N   1 
ATOM   3269  C  CA  . CYS B 1 117 ? -31.505 15.451  -30.599 1.00 22.02  ? 117 CYS B CA  1 
ATOM   3270  C  C   . CYS B 1 117 ? -33.010 15.250  -30.607 1.00 24.50  ? 117 CYS B C   1 
ATOM   3271  O  O   . CYS B 1 117 ? -33.505 14.126  -30.468 1.00 21.69  ? 117 CYS B O   1 
ATOM   3272  C  CB  . CYS B 1 117 ? -30.996 15.505  -32.041 1.00 24.91  ? 117 CYS B CB  1 
ATOM   3273  S  SG  . CYS B 1 117 ? -29.309 16.045  -32.208 1.00 23.50  ? 117 CYS B SG  1 
ATOM   3274  N  N   . TYR B 1 118 ? -33.732 16.368  -30.751 1.00 24.21  ? 118 TYR B N   1 
ATOM   3275  C  CA  . TYR B 1 118 ? -35.178 16.363  -30.932 1.00 22.01  ? 118 TYR B CA  1 
ATOM   3276  C  C   . TYR B 1 118 ? -35.526 17.466  -31.907 1.00 23.99  ? 118 TYR B C   1 
ATOM   3277  O  O   . TYR B 1 118 ? -35.139 18.621  -31.693 1.00 28.57  ? 118 TYR B O   1 
ATOM   3278  C  CB  . TYR B 1 118 ? -35.925 16.549  -29.605 1.00 20.07  ? 118 TYR B CB  1 
ATOM   3279  C  CG  . TYR B 1 118 ? -35.560 15.460  -28.615 1.00 25.71  ? 118 TYR B CG  1 
ATOM   3280  C  CD1 . TYR B 1 118 ? -36.209 14.236  -28.637 1.00 20.45  ? 118 TYR B CD1 1 
ATOM   3281  C  CD2 . TYR B 1 118 ? -34.536 15.648  -27.698 1.00 21.33  ? 118 TYR B CD2 1 
ATOM   3282  C  CE1 . TYR B 1 118 ? -35.854 13.223  -27.759 1.00 24.66  ? 118 TYR B CE1 1 
ATOM   3283  C  CE2 . TYR B 1 118 ? -34.174 14.668  -26.824 1.00 19.05  ? 118 TYR B CE2 1 
ATOM   3284  C  CZ  . TYR B 1 118 ? -34.841 13.447  -26.849 1.00 26.06  ? 118 TYR B CZ  1 
ATOM   3285  O  OH  . TYR B 1 118 ? -34.480 12.459  -25.964 1.00 26.74  ? 118 TYR B OH  1 
ATOM   3286  N  N   . ASN B 1 119 ? -36.246 17.108  -32.973 1.00 22.08  ? 119 ASN B N   1 
ATOM   3287  C  CA  . ASN B 1 119 ? -36.620 18.065  -34.013 1.00 24.94  ? 119 ASN B CA  1 
ATOM   3288  C  C   . ASN B 1 119 ? -35.389 18.695  -34.661 1.00 24.60  ? 119 ASN B C   1 
ATOM   3289  O  O   . ASN B 1 119 ? -35.353 19.901  -34.907 1.00 25.52  ? 119 ASN B O   1 
ATOM   3290  C  CB  . ASN B 1 119 ? -37.536 19.160  -33.458 1.00 29.90  ? 119 ASN B CB  1 
ATOM   3291  C  CG  . ASN B 1 119 ? -38.626 18.613  -32.608 1.00 28.11  ? 119 ASN B CG  1 
ATOM   3292  O  OD1 . ASN B 1 119 ? -39.537 17.948  -33.109 1.00 29.60  ? 119 ASN B OD1 1 
ATOM   3293  N  ND2 . ASN B 1 119 ? -38.537 18.861  -31.304 1.00 28.13  ? 119 ASN B ND2 1 
ATOM   3294  N  N   . GLY B 1 120 ? -34.364 17.882  -34.899 1.00 21.90  ? 120 GLY B N   1 
ATOM   3295  C  CA  . GLY B 1 120 ? -33.154 18.336  -35.541 1.00 18.05  ? 120 GLY B CA  1 
ATOM   3296  C  C   . GLY B 1 120 ? -32.305 19.288  -34.741 1.00 20.53  ? 120 GLY B C   1 
ATOM   3297  O  O   . GLY B 1 120 ? -31.423 19.918  -35.313 1.00 24.98  ? 120 GLY B O   1 
ATOM   3298  N  N   . SER B 1 121 ? -32.528 19.425  -33.440 1.00 25.58  ? 121 SER B N   1 
ATOM   3299  C  CA  . SER B 1 121 ? -31.653 20.279  -32.651 1.00 23.51  ? 121 SER B CA  1 
ATOM   3300  C  C   . SER B 1 121 ? -31.123 19.535  -31.433 1.00 20.41  ? 121 SER B C   1 
ATOM   3301  O  O   . SER B 1 121 ? -31.786 18.645  -30.896 1.00 21.69  ? 121 SER B O   1 
ATOM   3302  C  CB  . SER B 1 121 ? -32.375 21.558  -32.196 1.00 30.28  ? 121 SER B CB  1 
ATOM   3303  O  OG  . SER B 1 121 ? -33.642 21.240  -31.653 1.00 34.01  ? 121 SER B OG  1 
ATOM   3304  N  N   . PRO B 1 122 ? -29.903 19.856  -31.014 1.00 25.90  ? 122 PRO B N   1 
ATOM   3305  C  CA  . PRO B 1 122 ? -29.238 19.076  -29.965 1.00 24.49  ? 122 PRO B CA  1 
ATOM   3306  C  C   . PRO B 1 122 ? -29.751 19.372  -28.570 1.00 26.61  ? 122 PRO B C   1 
ATOM   3307  O  O   . PRO B 1 122 ? -29.960 20.530  -28.198 1.00 23.67  ? 122 PRO B O   1 
ATOM   3308  C  CB  . PRO B 1 122 ? -27.777 19.513  -30.093 1.00 29.85  ? 122 PRO B CB  1 
ATOM   3309  C  CG  . PRO B 1 122 ? -27.877 20.943  -30.570 1.00 27.53  ? 122 PRO B CG  1 
ATOM   3310  C  CD  . PRO B 1 122 ? -29.037 20.932  -31.540 1.00 25.85  ? 122 PRO B CD  1 
ATOM   3311  N  N   . SER B 1 123 ? -29.865 18.307  -27.770 1.00 31.40  ? 123 SER B N   1 
ATOM   3312  C  CA  . SER B 1 123 ? -30.285 18.392  -26.370 1.00 28.57  ? 123 SER B CA  1 
ATOM   3313  C  C   . SER B 1 123 ? -29.153 18.146  -25.380 1.00 21.97  ? 123 SER B C   1 
ATOM   3314  O  O   . SER B 1 123 ? -29.043 18.863  -24.379 1.00 22.33  ? 123 SER B O   1 
ATOM   3315  C  CB  . SER B 1 123 ? -31.414 17.391  -26.084 1.00 27.47  ? 123 SER B CB  1 
ATOM   3316  O  OG  . SER B 1 123 ? -31.799 17.462  -24.713 1.00 28.51  ? 123 SER B OG  1 
ATOM   3317  N  N   . GLY B 1 124 ? -28.281 17.186  -25.650 1.00 20.21  ? 124 GLY B N   1 
ATOM   3318  C  CA  . GLY B 1 124 ? -27.231 16.867  -24.702 1.00 18.83  ? 124 GLY B CA  1 
ATOM   3319  C  C   . GLY B 1 124 ? -26.272 15.884  -25.328 1.00 17.20  ? 124 GLY B C   1 
ATOM   3320  O  O   . GLY B 1 124 ? -26.539 15.299  -26.380 1.00 17.34  ? 124 GLY B O   1 
ATOM   3321  N  N   . VAL B 1 125 ? -25.120 15.750  -24.695 1.00 16.80  ? 125 VAL B N   1 
ATOM   3322  C  CA  . VAL B 1 125 ? -24.070 14.874  -25.185 1.00 19.24  ? 125 VAL B CA  1 
ATOM   3323  C  C   . VAL B 1 125 ? -23.620 14.001  -24.017 1.00 19.82  ? 125 VAL B C   1 
ATOM   3324  O  O   . VAL B 1 125 ? -23.556 14.465  -22.873 1.00 18.71  ? 125 VAL B O   1 
ATOM   3325  C  CB  . VAL B 1 125 ? -22.911 15.687  -25.809 1.00 18.09  ? 125 VAL B CB  1 
ATOM   3326  C  CG1 . VAL B 1 125 ? -22.193 16.507  -24.769 1.00 20.93  ? 125 VAL B CG1 1 
ATOM   3327  C  CG2 . VAL B 1 125 ? -21.946 14.794  -26.581 1.00 16.05  ? 125 VAL B CG2 1 
ATOM   3328  N  N   . TYR B 1 126 ? -23.409 12.716  -24.282 1.00 21.19  ? 126 TYR B N   1 
ATOM   3329  C  CA  . TYR B 1 126 ? -22.976 11.799  -23.233 1.00 20.59  ? 126 TYR B CA  1 
ATOM   3330  C  C   . TYR B 1 126 ? -22.236 10.630  -23.864 1.00 18.80  ? 126 TYR B C   1 
ATOM   3331  O  O   . TYR B 1 126 ? -22.371 10.371  -25.059 1.00 23.80  ? 126 TYR B O   1 
ATOM   3332  C  CB  . TYR B 1 126 ? -24.153 11.302  -22.381 1.00 20.69  ? 126 TYR B CB  1 
ATOM   3333  C  CG  . TYR B 1 126 ? -25.304 10.651  -23.122 1.00 20.29  ? 126 TYR B CG  1 
ATOM   3334  C  CD1 . TYR B 1 126 ? -25.264 9.318   -23.502 1.00 24.47  ? 126 TYR B CD1 1 
ATOM   3335  C  CD2 . TYR B 1 126 ? -26.453 11.361  -23.395 1.00 23.62  ? 126 TYR B CD2 1 
ATOM   3336  C  CE1 . TYR B 1 126 ? -26.335 8.735   -24.172 1.00 22.62  ? 126 TYR B CE1 1 
ATOM   3337  C  CE2 . TYR B 1 126 ? -27.515 10.791  -24.042 1.00 19.80  ? 126 TYR B CE2 1 
ATOM   3338  C  CZ  . TYR B 1 126 ? -27.456 9.492   -24.431 1.00 23.29  ? 126 TYR B CZ  1 
ATOM   3339  O  OH  . TYR B 1 126 ? -28.543 8.971   -25.081 1.00 23.60  ? 126 TYR B OH  1 
ATOM   3340  N  N   . GLN B 1 127 ? -21.425 9.956   -23.055 1.00 22.34  ? 127 GLN B N   1 
ATOM   3341  C  CA  . GLN B 1 127 ? -20.757 8.727   -23.461 1.00 25.92  ? 127 GLN B CA  1 
ATOM   3342  C  C   . GLN B 1 127 ? -21.604 7.508   -23.134 1.00 29.40  ? 127 GLN B C   1 
ATOM   3343  O  O   . GLN B 1 127 ? -22.325 7.467   -22.133 1.00 33.58  ? 127 GLN B O   1 
ATOM   3344  C  CB  . GLN B 1 127 ? -19.409 8.551   -22.761 1.00 25.63  ? 127 GLN B CB  1 
ATOM   3345  C  CG  . GLN B 1 127 ? -18.324 9.398   -23.307 1.00 26.90  ? 127 GLN B CG  1 
ATOM   3346  C  CD  . GLN B 1 127 ? -17.790 8.918   -24.629 1.00 26.82  ? 127 GLN B CD  1 
ATOM   3347  O  OE1 . GLN B 1 127 ? -18.071 9.515   -25.668 1.00 29.23  ? 127 GLN B OE1 1 
ATOM   3348  N  NE2 . GLN B 1 127 ? -16.969 7.880   -24.602 1.00 25.57  ? 127 GLN B NE2 1 
ATOM   3349  N  N   . CYS B 1 128 ? -21.487 6.494   -23.977 1.00 31.19  ? 128 CYS B N   1 
ATOM   3350  C  CA  . CYS B 1 128 ? -21.921 5.165   -23.590 1.00 26.16  ? 128 CYS B CA  1 
ATOM   3351  C  C   . CYS B 1 128 ? -21.128 4.152   -24.391 1.00 23.39  ? 128 CYS B C   1 
ATOM   3352  O  O   . CYS B 1 128 ? -20.320 4.502   -25.253 1.00 24.82  ? 128 CYS B O   1 
ATOM   3353  C  CB  . CYS B 1 128 ? -23.436 4.998   -23.735 1.00 31.20  ? 128 CYS B CB  1 
ATOM   3354  S  SG  . CYS B 1 128 ? -24.192 5.635   -25.223 1.00 38.05  ? 128 CYS B SG  1 
ATOM   3355  N  N   . ALA B 1 129 ? -21.371 2.880   -24.105 1.00 29.26  ? 129 ALA B N   1 
ATOM   3356  C  CA  . ALA B 1 129 ? -20.570 1.797   -24.653 1.00 25.02  ? 129 ALA B CA  1 
ATOM   3357  C  C   . ALA B 1 129 ? -21.470 0.812   -25.369 1.00 24.71  ? 129 ALA B C   1 
ATOM   3358  O  O   . ALA B 1 129 ? -22.585 0.533   -24.918 1.00 28.17  ? 129 ALA B O   1 
ATOM   3359  C  CB  . ALA B 1 129 ? -19.793 1.071   -23.537 1.00 26.13  ? 129 ALA B CB  1 
ATOM   3360  N  N   . MET B 1 130 ? -20.962 0.281   -26.467 1.00 26.52  ? 130 MET B N   1 
ATOM   3361  C  CA  . MET B 1 130 ? -21.681 -0.816  -27.135 1.00 22.99  ? 130 MET B CA  1 
ATOM   3362  C  C   . MET B 1 130 ? -21.484 -2.044  -26.254 1.00 24.32  ? 130 MET B C   1 
ATOM   3363  O  O   . MET B 1 130 ? -20.350 -2.439  -26.031 1.00 28.86  ? 130 MET B O   1 
ATOM   3364  C  CB  . MET B 1 130 ? -21.126 -1.090  -28.532 1.00 30.09  ? 130 MET B CB  1 
ATOM   3365  C  CG  . MET B 1 130 ? -21.812 -2.234  -29.248 1.00 29.31  ? 130 MET B CG  1 
ATOM   3366  S  SD  . MET B 1 130 ? -23.579 -1.939  -29.439 1.00 32.42  ? 130 MET B SD  1 
ATOM   3367  C  CE  . MET B 1 130 ? -23.558 -0.493  -30.493 1.00 27.68  ? 130 MET B CE  1 
ATOM   3368  N  N   . ARG B 1 131 ? -22.575 -2.594  -25.763 1.00 25.99  ? 131 ARG B N   1 
ATOM   3369  C  CA  . ARG B 1 131 ? -22.499 -3.754  -24.853 1.00 24.81  ? 131 ARG B CA  1 
ATOM   3370  C  C   . ARG B 1 131 ? -22.409 -5.062  -25.647 1.00 25.74  ? 131 ARG B C   1 
ATOM   3371  O  O   . ARG B 1 131 ? -22.645 -5.032  -26.857 1.00 21.18  ? 131 ARG B O   1 
ATOM   3372  C  CB  . ARG B 1 131 ? -23.680 -3.701  -23.887 1.00 24.17  ? 131 ARG B CB  1 
ATOM   3373  C  CG  . ARG B 1 131 ? -24.047 -2.309  -23.397 1.00 21.79  ? 131 ARG B CG  1 
ATOM   3374  C  CD  . ARG B 1 131 ? -23.249 -1.854  -22.197 1.00 27.36  ? 131 ARG B CD  1 
ATOM   3375  N  NE  . ARG B 1 131 ? -22.820 -2.942  -21.336 1.00 31.72  ? 131 ARG B NE  1 
ATOM   3376  C  CZ  . ARG B 1 131 ? -21.887 -2.828  -20.403 1.00 32.74  ? 131 ARG B CZ  1 
ATOM   3377  N  NH1 . ARG B 1 131 ? -21.283 -1.670  -20.210 1.00 27.22  ? 131 ARG B NH1 1 
ATOM   3378  N  NH2 . ARG B 1 131 ? -21.560 -3.870  -19.664 1.00 29.33  ? 131 ARG B NH2 1 
ATOM   3379  N  N   . HIS B 1 132 ? -22.070 -6.155  -24.966 1.00 26.60  ? 132 HIS B N   1 
ATOM   3380  C  CA  . HIS B 1 132 ? -21.879 -7.480  -25.608 1.00 29.08  ? 132 HIS B CA  1 
ATOM   3381  C  C   . HIS B 1 132 ? -23.220 -8.049  -26.087 1.00 27.81  ? 132 HIS B C   1 
ATOM   3382  O  O   . HIS B 1 132 ? -23.184 -8.924  -26.939 1.00 29.46  ? 132 HIS B O   1 
ATOM   3383  C  CB  . HIS B 1 132 ? -21.063 -8.376  -24.663 1.00 25.41  ? 132 HIS B CB  1 
ATOM   3384  C  CG  . HIS B 1 132 ? -19.613 -8.040  -24.639 1.00 23.70  ? 132 HIS B CG  1 
ATOM   3385  N  ND1 . HIS B 1 132 ? -19.057 -7.260  -23.656 1.00 30.76  ? 132 HIS B ND1 1 
ATOM   3386  C  CD2 . HIS B 1 132 ? -18.610 -8.362  -25.479 1.00 23.44  ? 132 HIS B CD2 1 
ATOM   3387  C  CE1 . HIS B 1 132 ? -17.771 -7.115  -23.888 1.00 29.41  ? 132 HIS B CE1 1 
ATOM   3388  N  NE2 . HIS B 1 132 ? -17.474 -7.779  -25.000 1.00 30.05  ? 132 HIS B NE2 1 
ATOM   3389  N  N   . ASN B 1 133 ? -24.341 -7.522  -25.591 1.00 26.16  ? 133 ASN B N   1 
ATOM   3390  C  CA  . ASN B 1 133 ? -25.684 -7.939  -26.068 1.00 26.43  ? 133 ASN B CA  1 
ATOM   3391  C  C   . ASN B 1 133 ? -26.148 -6.954  -27.144 1.00 28.65  ? 133 ASN B C   1 
ATOM   3392  O  O   . ASN B 1 133 ? -27.319 -7.005  -27.510 1.00 34.08  ? 133 ASN B O   1 
ATOM   3393  C  CB  . ASN B 1 133 ? -26.668 -8.080  -24.906 1.00 32.05  ? 133 ASN B CB  1 
ATOM   3394  C  CG  . ASN B 1 133 ? -26.938 -6.778  -24.178 1.00 31.66  ? 133 ASN B CG  1 
ATOM   3395  O  OD1 . ASN B 1 133 ? -26.309 -5.759  -24.441 1.00 21.49  ? 133 ASN B OD1 1 
ATOM   3396  N  ND2 . ASN B 1 133 ? -27.883 -6.806  -23.258 1.00 28.58  ? 133 ASN B ND2 1 
ATOM   3397  N  N   . PHE B 1 134 ? -25.268 -6.061  -27.579 1.00 28.60  ? 134 PHE B N   1 
ATOM   3398  C  CA  . PHE B 1 134 ? -25.559 -5.122  -28.696 1.00 23.45  ? 134 PHE B CA  1 
ATOM   3399  C  C   . PHE B 1 134 ? -26.590 -4.059  -28.329 1.00 25.45  ? 134 PHE B C   1 
ATOM   3400  O  O   . PHE B 1 134 ? -27.300 -3.621  -29.212 1.00 30.07  ? 134 PHE B O   1 
ATOM   3401  C  CB  . PHE B 1 134 ? -25.867 -5.908  -29.969 1.00 24.02  ? 134 PHE B CB  1 
ATOM   3402  C  CG  . PHE B 1 134 ? -24.717 -6.767  -30.417 1.00 26.95  ? 134 PHE B CG  1 
ATOM   3403  C  CD1 . PHE B 1 134 ? -23.656 -6.218  -31.114 1.00 32.45  ? 134 PHE B CD1 1 
ATOM   3404  C  CD2 . PHE B 1 134 ? -24.677 -8.114  -30.106 1.00 28.41  ? 134 PHE B CD2 1 
ATOM   3405  C  CE1 . PHE B 1 134 ? -22.589 -7.006  -31.514 1.00 35.48  ? 134 PHE B CE1 1 
ATOM   3406  C  CE2 . PHE B 1 134 ? -23.608 -8.898  -30.504 1.00 31.99  ? 134 PHE B CE2 1 
ATOM   3407  C  CZ  . PHE B 1 134 ? -22.566 -8.343  -31.205 1.00 27.22  ? 134 PHE B CZ  1 
ATOM   3408  N  N   . THR B 1 135 ? -26.659 -3.681  -27.066 1.00 22.43  ? 135 THR B N   1 
ATOM   3409  C  CA  . THR B 1 135 ? -27.506 -2.564  -26.692 1.00 23.17  ? 135 THR B CA  1 
ATOM   3410  C  C   . THR B 1 135 ? -26.609 -1.447  -26.172 1.00 23.25  ? 135 THR B C   1 
ATOM   3411  O  O   . THR B 1 135 ? -25.386 -1.589  -26.082 1.00 27.67  ? 135 THR B O   1 
ATOM   3412  C  CB  . THR B 1 135 ? -28.537 -2.976  -25.635 1.00 20.96  ? 135 THR B CB  1 
ATOM   3413  O  OG1 . THR B 1 135 ? -27.841 -3.450  -24.482 1.00 25.55  ? 135 THR B OG1 1 
ATOM   3414  C  CG2 . THR B 1 135 ? -29.435 -4.105  -26.165 1.00 23.27  ? 135 THR B CG2 1 
ATOM   3415  N  N   . ILE B 1 136 ? -27.204 -0.306  -25.867 1.00 19.62  ? 136 ILE B N   1 
ATOM   3416  C  CA  . ILE B 1 136 ? -26.478 0.737   -25.171 1.00 20.16  ? 136 ILE B CA  1 
ATOM   3417  C  C   . ILE B 1 136 ? -27.379 1.256   -24.066 1.00 20.20  ? 136 ILE B C   1 
ATOM   3418  O  O   . ILE B 1 136 ? -28.600 1.108   -24.109 1.00 23.08  ? 136 ILE B O   1 
ATOM   3419  C  CB  . ILE B 1 136 ? -26.014 1.871   -26.124 1.00 18.16  ? 136 ILE B CB  1 
ATOM   3420  C  CG1 . ILE B 1 136 ? -27.196 2.633   -26.707 1.00 15.96  ? 136 ILE B CG1 1 
ATOM   3421  C  CG2 . ILE B 1 136 ? -25.159 1.309   -27.270 1.00 20.51  ? 136 ILE B CG2 1 
ATOM   3422  C  CD1 . ILE B 1 136 ? -26.787 3.925   -27.399 1.00 18.97  ? 136 ILE B CD1 1 
ATOM   3423  N  N   . LYS B 1 137 ? -26.761 1.853   -23.058 1.00 21.28  ? 137 LYS B N   1 
ATOM   3424  C  CA  . LYS B 1 137 ? -27.486 2.465   -21.948 1.00 21.92  ? 137 LYS B CA  1 
ATOM   3425  C  C   . LYS B 1 137 ? -27.456 3.971   -22.190 1.00 27.06  ? 137 LYS B C   1 
ATOM   3426  O  O   . LYS B 1 137 ? -26.548 4.679   -21.762 1.00 32.17  ? 137 LYS B O   1 
ATOM   3427  C  CB  . LYS B 1 137 ? -26.895 2.047   -20.603 1.00 22.98  ? 137 LYS B CB  1 
ATOM   3428  C  CG  . LYS B 1 137 ? -26.989 0.524   -20.400 1.00 32.60  ? 137 LYS B CG  1 
ATOM   3429  C  CD  . LYS B 1 137 ? -26.288 -0.045  -19.169 1.00 38.33  ? 137 LYS B CD  1 
ATOM   3430  C  CE  . LYS B 1 137 ? -26.799 -1.503  -18.950 1.00 45.03  ? 137 LYS B CE  1 
ATOM   3431  N  NZ  . LYS B 1 137 ? -26.193 -2.290  -17.822 1.00 44.75  ? 137 LYS B NZ  1 
ATOM   3432  N  N   . GLY B 1 138 ? -28.441 4.452   -22.942 1.00 26.42  ? 138 GLY B N   1 
ATOM   3433  C  CA  . GLY B 1 138 ? -28.552 5.850   -23.267 1.00 25.63  ? 138 GLY B CA  1 
ATOM   3434  C  C   . GLY B 1 138 ? -29.710 6.516   -22.550 1.00 28.62  ? 138 GLY B C   1 
ATOM   3435  O  O   . GLY B 1 138 ? -30.299 5.976   -21.610 1.00 27.72  ? 138 GLY B O   1 
ATOM   3436  N  N   . SER B 1 139 ? -30.049 7.707   -23.038 1.00 22.84  ? 139 SER B N   1 
ATOM   3437  C  CA  . SER B 1 139 ? -31.148 8.510   -22.499 1.00 23.68  ? 139 SER B CA  1 
ATOM   3438  C  C   . SER B 1 139 ? -31.855 9.085   -23.722 1.00 25.21  ? 139 SER B C   1 
ATOM   3439  O  O   . SER B 1 139 ? -31.361 10.031  -24.349 1.00 26.80  ? 139 SER B O   1 
ATOM   3440  C  CB  . SER B 1 139 ? -30.618 9.585   -21.542 1.00 24.79  ? 139 SER B CB  1 
ATOM   3441  O  OG  . SER B 1 139 ? -31.555 10.599  -21.265 1.00 23.97  ? 139 SER B OG  1 
ATOM   3442  N  N   . PHE B 1 140 ? -32.970 8.460   -24.098 1.00 25.61  ? 140 PHE B N   1 
ATOM   3443  C  CA  . PHE B 1 140 ? -33.648 8.702   -25.365 1.00 22.75  ? 140 PHE B CA  1 
ATOM   3444  C  C   . PHE B 1 140 ? -35.144 8.784   -25.109 1.00 26.99  ? 140 PHE B C   1 
ATOM   3445  O  O   . PHE B 1 140 ? -35.707 7.905   -24.453 1.00 24.27  ? 140 PHE B O   1 
ATOM   3446  C  CB  . PHE B 1 140 ? -33.376 7.579   -26.382 1.00 24.74  ? 140 PHE B CB  1 
ATOM   3447  C  CG  . PHE B 1 140 ? -31.961 7.532   -26.892 1.00 25.24  ? 140 PHE B CG  1 
ATOM   3448  C  CD1 . PHE B 1 140 ? -31.494 8.501   -27.778 1.00 22.10  ? 140 PHE B CD1 1 
ATOM   3449  C  CD2 . PHE B 1 140 ? -31.106 6.513   -26.510 1.00 20.47  ? 140 PHE B CD2 1 
ATOM   3450  C  CE1 . PHE B 1 140 ? -30.203 8.456   -28.250 1.00 23.25  ? 140 PHE B CE1 1 
ATOM   3451  C  CE2 . PHE B 1 140 ? -29.803 6.463   -26.994 1.00 22.15  ? 140 PHE B CE2 1 
ATOM   3452  C  CZ  . PHE B 1 140 ? -29.351 7.436   -27.857 1.00 19.12  ? 140 PHE B CZ  1 
ATOM   3453  N  N   . LEU B 1 141 ? -35.777 9.824   -25.629 1.00 22.76  ? 141 LEU B N   1 
ATOM   3454  C  CA  . LEU B 1 141 ? -37.211 10.051  -25.510 1.00 29.31  ? 141 LEU B CA  1 
ATOM   3455  C  C   . LEU B 1 141 ? -37.856 9.992   -26.894 1.00 23.93  ? 141 LEU B C   1 
ATOM   3456  O  O   . LEU B 1 141 ? -37.184 9.775   -27.908 1.00 24.77  ? 141 LEU B O   1 
ATOM   3457  C  CB  . LEU B 1 141 ? -37.489 11.406  -24.855 1.00 24.84  ? 141 LEU B CB  1 
ATOM   3458  C  CG  . LEU B 1 141 ? -36.896 11.680  -23.473 1.00 31.22  ? 141 LEU B CG  1 
ATOM   3459  C  CD1 . LEU B 1 141 ? -37.048 13.180  -23.103 1.00 31.88  ? 141 LEU B CD1 1 
ATOM   3460  C  CD2 . LEU B 1 141 ? -37.524 10.805  -22.422 1.00 26.51  ? 141 LEU B CD2 1 
ATOM   3461  N  N   . ASN B 1 142 ? -39.177 10.171  -26.925 1.00 23.91  ? 142 ASN B N   1 
ATOM   3462  C  CA  . ASN B 1 142 ? -39.894 10.296  -28.189 1.00 25.29  ? 142 ASN B CA  1 
ATOM   3463  C  C   . ASN B 1 142 ? -39.290 11.405  -29.029 1.00 30.52  ? 142 ASN B C   1 
ATOM   3464  O  O   . ASN B 1 142 ? -39.121 12.538  -28.554 1.00 23.00  ? 142 ASN B O   1 
ATOM   3465  C  CB  . ASN B 1 142 ? -41.365 10.622  -27.960 1.00 30.17  ? 142 ASN B CB  1 
ATOM   3466  C  CG  . ASN B 1 142 ? -42.130 9.472   -27.367 1.00 32.75  ? 142 ASN B CG  1 
ATOM   3467  O  OD1 . ASN B 1 142 ? -41.764 8.303   -27.546 1.00 29.87  ? 142 ASN B OD1 1 
ATOM   3468  N  ND2 . ASN B 1 142 ? -43.223 9.791   -26.675 1.00 31.73  ? 142 ASN B ND2 1 
ATOM   3469  N  N   . GLY B 1 143 ? -38.986 11.077  -30.288 1.00 28.15  ? 143 GLY B N   1 
ATOM   3470  C  CA  . GLY B 1 143 ? -38.396 12.034  -31.193 1.00 23.71  ? 143 GLY B CA  1 
ATOM   3471  C  C   . GLY B 1 143 ? -36.893 11.987  -31.248 1.00 24.51  ? 143 GLY B C   1 
ATOM   3472  O  O   . GLY B 1 143 ? -36.300 12.724  -32.047 1.00 26.22  ? 143 GLY B O   1 
ATOM   3473  N  N   . SER B 1 144 ? -36.258 11.137  -30.432 1.00 22.25  ? 144 SER B N   1 
ATOM   3474  C  CA  . SER B 1 144 ? -34.810 11.010  -30.426 1.00 17.05  ? 144 SER B CA  1 
ATOM   3475  C  C   . SER B 1 144 ? -34.271 10.150  -31.563 1.00 21.03  ? 144 SER B C   1 
ATOM   3476  O  O   . SER B 1 144 ? -33.063 10.185  -31.810 1.00 23.45  ? 144 SER B O   1 
ATOM   3477  C  CB  . SER B 1 144 ? -34.344 10.431  -29.074 1.00 25.47  ? 144 SER B CB  1 
ATOM   3478  O  OG  . SER B 1 144 ? -34.938 9.166   -28.771 1.00 21.30  ? 144 SER B OG  1 
ATOM   3479  N  N   . CYS B 1 145 ? -35.116 9.408   -32.274 1.00 21.87  ? 145 CYS B N   1 
ATOM   3480  C  CA  . CYS B 1 145 ? -34.628 8.565   -33.358 1.00 19.78  ? 145 CYS B CA  1 
ATOM   3481  C  C   . CYS B 1 145 ? -33.908 9.388   -34.431 1.00 25.59  ? 145 CYS B C   1 
ATOM   3482  O  O   . CYS B 1 145 ? -34.286 10.531  -34.739 1.00 24.43  ? 145 CYS B O   1 
ATOM   3483  C  CB  . CYS B 1 145 ? -35.789 7.789   -33.954 1.00 22.47  ? 145 CYS B CB  1 
ATOM   3484  S  SG  . CYS B 1 145 ? -36.421 6.526   -32.777 1.00 29.15  ? 145 CYS B SG  1 
ATOM   3485  N  N   . GLY B 1 146 ? -32.834 8.819   -34.979 1.00 19.94  ? 146 GLY B N   1 
ATOM   3486  C  CA  . GLY B 1 146 ? -31.978 9.552   -35.879 1.00 23.62  ? 146 GLY B CA  1 
ATOM   3487  C  C   . GLY B 1 146 ? -30.841 10.301  -35.220 1.00 22.65  ? 146 GLY B C   1 
ATOM   3488  O  O   . GLY B 1 146 ? -29.957 10.787  -35.931 1.00 21.26  ? 146 GLY B O   1 
ATOM   3489  N  N   . SER B 1 147 ? -30.838 10.423  -33.892 1.00 22.17  ? 147 SER B N   1 
ATOM   3490  C  CA  . SER B 1 147 ? -29.647 10.881  -33.189 1.00 19.90  ? 147 SER B CA  1 
ATOM   3491  C  C   . SER B 1 147 ? -28.528 9.861   -33.409 1.00 22.50  ? 147 SER B C   1 
ATOM   3492  O  O   . SER B 1 147 ? -28.779 8.661   -33.603 1.00 21.42  ? 147 SER B O   1 
ATOM   3493  C  CB  . SER B 1 147 ? -29.930 11.053  -31.690 1.00 20.03  ? 147 SER B CB  1 
ATOM   3494  O  OG  . SER B 1 147 ? -31.040 11.917  -31.442 1.00 18.94  ? 147 SER B OG  1 
ATOM   3495  N  N   . VAL B 1 148 ? -27.289 10.346  -33.427 1.00 15.91  ? 148 VAL B N   1 
ATOM   3496  C  CA  . VAL B 1 148 ? -26.146 9.540   -33.820 1.00 14.56  ? 148 VAL B CA  1 
ATOM   3497  C  C   . VAL B 1 148 ? -25.110 9.464   -32.707 1.00 16.46  ? 148 VAL B C   1 
ATOM   3498  O  O   . VAL B 1 148 ? -25.034 10.324  -31.818 1.00 20.24  ? 148 VAL B O   1 
ATOM   3499  C  CB  . VAL B 1 148 ? -25.503 10.075  -35.115 1.00 19.96  ? 148 VAL B CB  1 
ATOM   3500  C  CG1 . VAL B 1 148 ? -26.471 9.939   -36.274 1.00 12.44  ? 148 VAL B CG1 1 
ATOM   3501  C  CG2 . VAL B 1 148 ? -25.120 11.520  -34.920 1.00 16.43  ? 148 VAL B CG2 1 
ATOM   3502  N  N   . GLY B 1 149 ? -24.325 8.392   -32.759 1.00 14.18  ? 149 GLY B N   1 
ATOM   3503  C  CA  . GLY B 1 149 ? -23.148 8.222   -31.930 1.00 14.93  ? 149 GLY B CA  1 
ATOM   3504  C  C   . GLY B 1 149 ? -21.895 8.281   -32.789 1.00 20.09  ? 149 GLY B C   1 
ATOM   3505  O  O   . GLY B 1 149 ? -21.908 7.890   -33.960 1.00 18.47  ? 149 GLY B O   1 
ATOM   3506  N  N   . PHE B 1 150 ? -20.785 8.723   -32.200 1.00 20.79  ? 150 PHE B N   1 
ATOM   3507  C  CA  . PHE B 1 150 ? -19.620 9.047   -33.018 1.00 21.03  ? 150 PHE B CA  1 
ATOM   3508  C  C   . PHE B 1 150 ? -18.366 9.088   -32.159 1.00 20.55  ? 150 PHE B C   1 
ATOM   3509  O  O   . PHE B 1 150 ? -18.429 9.255   -30.940 1.00 20.97  ? 150 PHE B O   1 
ATOM   3510  C  CB  . PHE B 1 150 ? -19.827 10.389  -33.735 1.00 18.51  ? 150 PHE B CB  1 
ATOM   3511  C  CG  . PHE B 1 150 ? -20.030 11.531  -32.790 1.00 20.88  ? 150 PHE B CG  1 
ATOM   3512  C  CD1 . PHE B 1 150 ? -21.281 11.750  -32.210 1.00 20.19  ? 150 PHE B CD1 1 
ATOM   3513  C  CD2 . PHE B 1 150 ? -18.985 12.375  -32.468 1.00 17.89  ? 150 PHE B CD2 1 
ATOM   3514  C  CE1 . PHE B 1 150 ? -21.469 12.797  -31.320 1.00 23.47  ? 150 PHE B CE1 1 
ATOM   3515  C  CE2 . PHE B 1 150 ? -19.164 13.428  -31.599 1.00 15.22  ? 150 PHE B CE2 1 
ATOM   3516  C  CZ  . PHE B 1 150 ? -20.393 13.653  -31.023 1.00 19.03  ? 150 PHE B CZ  1 
ATOM   3517  N  N   . ASN B 1 151 ? -17.223 8.935   -32.819 1.00 18.62  ? 151 ASN B N   1 
ATOM   3518  C  CA  . ASN B 1 151 ? -15.924 9.221   -32.237 1.00 21.62  ? 151 ASN B CA  1 
ATOM   3519  C  C   . ASN B 1 151 ? -15.249 10.283  -33.104 1.00 24.41  ? 151 ASN B C   1 
ATOM   3520  O  O   . ASN B 1 151 ? -15.623 10.495  -34.261 1.00 23.81  ? 151 ASN B O   1 
ATOM   3521  C  CB  . ASN B 1 151 ? -15.048 7.959   -32.148 1.00 18.77  ? 151 ASN B CB  1 
ATOM   3522  C  CG  . ASN B 1 151 ? -15.508 6.988   -31.037 1.00 25.39  ? 151 ASN B CG  1 
ATOM   3523  O  OD1 . ASN B 1 151 ? -15.223 7.197   -29.850 1.00 27.28  ? 151 ASN B OD1 1 
ATOM   3524  N  ND2 . ASN B 1 151 ? -16.222 5.927   -31.426 1.00 22.20  ? 151 ASN B ND2 1 
ATOM   3525  N  N   . ILE B 1 152 ? -14.274 10.990  -32.542 1.00 21.58  ? 152 ILE B N   1 
ATOM   3526  C  CA  . ILE B 1 152 ? -13.531 11.967  -33.321 1.00 29.84  ? 152 ILE B CA  1 
ATOM   3527  C  C   . ILE B 1 152 ? -12.055 11.647  -33.221 1.00 29.24  ? 152 ILE B C   1 
ATOM   3528  O  O   . ILE B 1 152 ? -11.506 11.553  -32.124 1.00 34.98  ? 152 ILE B O   1 
ATOM   3529  C  CB  . ILE B 1 152 ? -13.801 13.408  -32.865 1.00 30.62  ? 152 ILE B CB  1 
ATOM   3530  C  CG1 . ILE B 1 152 ? -15.298 13.619  -32.681 1.00 24.86  ? 152 ILE B CG1 1 
ATOM   3531  C  CG2 . ILE B 1 152 ? -13.182 14.373  -33.869 1.00 28.35  ? 152 ILE B CG2 1 
ATOM   3532  C  CD1 . ILE B 1 152 ? -15.718 15.074  -32.478 1.00 30.12  ? 152 ILE B CD1 1 
ATOM   3533  N  N   . ASP B 1 153 ? -11.411 11.510  -34.363 1.00 36.36  ? 153 ASP B N   1 
ATOM   3534  C  CA  . ASP B 1 153 ? -9.979  11.272  -34.423 1.00 40.62  ? 153 ASP B CA  1 
ATOM   3535  C  C   . ASP B 1 153 ? -9.386  12.424  -35.225 1.00 42.87  ? 153 ASP B C   1 
ATOM   3536  O  O   . ASP B 1 153 ? -9.611  12.528  -36.437 1.00 43.22  ? 153 ASP B O   1 
ATOM   3537  C  CB  . ASP B 1 153 ? -9.692  9.908   -35.044 1.00 34.20  ? 153 ASP B CB  1 
ATOM   3538  C  CG  . ASP B 1 153 ? -8.228  9.527   -34.968 1.00 54.82  ? 153 ASP B CG  1 
ATOM   3539  O  OD1 . ASP B 1 153 ? -7.728  9.331   -33.828 1.00 55.43  ? 153 ASP B OD1 1 
ATOM   3540  O  OD2 . ASP B 1 153 ? -7.583  9.398   -36.040 1.00 50.68  ? 153 ASP B OD2 1 
ATOM   3541  N  N   . TYR B 1 154 ? -8.657  13.296  -34.536 1.00 45.39  ? 154 TYR B N   1 
ATOM   3542  C  CA  . TYR B 1 154 ? -8.117  14.513  -35.119 1.00 45.73  ? 154 TYR B CA  1 
ATOM   3543  C  C   . TYR B 1 154 ? -9.292  15.366  -35.575 1.00 46.01  ? 154 TYR B C   1 
ATOM   3544  O  O   . TYR B 1 154 ? -9.945  16.006  -34.748 1.00 51.87  ? 154 TYR B O   1 
ATOM   3545  C  CB  . TYR B 1 154 ? -7.142  14.172  -36.253 1.00 38.98  ? 154 TYR B CB  1 
ATOM   3546  C  CG  . TYR B 1 154 ? -6.057  13.219  -35.801 0.00 42.06  ? 154 TYR B CG  1 
ATOM   3547  C  CD1 . TYR B 1 154 ? -5.110  13.604  -34.860 0.00 40.93  ? 154 TYR B CD1 1 
ATOM   3548  C  CD2 . TYR B 1 154 ? -5.993  11.926  -36.300 0.00 42.29  ? 154 TYR B CD2 1 
ATOM   3549  C  CE1 . TYR B 1 154 ? -4.125  12.727  -34.437 0.00 40.73  ? 154 TYR B CE1 1 
ATOM   3550  C  CE2 . TYR B 1 154 ? -5.013  11.044  -35.884 0.00 41.95  ? 154 TYR B CE2 1 
ATOM   3551  C  CZ  . TYR B 1 154 ? -4.082  11.449  -34.954 0.00 41.35  ? 154 TYR B CZ  1 
ATOM   3552  O  OH  . TYR B 1 154 ? -3.106  10.570  -34.541 0.00 42.30  ? 154 TYR B OH  1 
ATOM   3553  N  N   . ASP B 1 155 ? -9.624  15.353  -36.858 1.00 42.11  ? 155 ASP B N   1 
ATOM   3554  C  CA  . ASP B 1 155 ? -10.791 16.095  -37.319 1.00 42.11  ? 155 ASP B CA  1 
ATOM   3555  C  C   . ASP B 1 155 ? -11.848 15.197  -37.948 1.00 37.34  ? 155 ASP B C   1 
ATOM   3556  O  O   . ASP B 1 155 ? -12.924 15.687  -38.310 1.00 33.91  ? 155 ASP B O   1 
ATOM   3557  C  CB  . ASP B 1 155 ? -10.381 17.212  -38.298 1.00 42.04  ? 155 ASP B CB  1 
ATOM   3558  C  CG  . ASP B 1 155 ? -9.462  16.715  -39.406 1.00 57.67  ? 155 ASP B CG  1 
ATOM   3559  O  OD1 . ASP B 1 155 ? -8.841  15.630  -39.232 1.00 59.12  ? 155 ASP B OD1 1 
ATOM   3560  O  OD2 . ASP B 1 155 ? -9.363  17.410  -40.447 1.00 52.31  ? 155 ASP B OD2 1 
ATOM   3561  N  N   . CYS B 1 156 ? -11.596 13.896  -38.051 1.00 36.77  ? 156 CYS B N   1 
ATOM   3562  C  CA  . CYS B 1 156 ? -12.502 13.003  -38.744 1.00 29.65  ? 156 CYS B CA  1 
ATOM   3563  C  C   . CYS B 1 156 ? -13.503 12.448  -37.737 1.00 32.06  ? 156 CYS B C   1 
ATOM   3564  O  O   . CYS B 1 156 ? -13.124 11.900  -36.696 1.00 30.04  ? 156 CYS B O   1 
ATOM   3565  C  CB  . CYS B 1 156 ? -11.720 11.874  -39.411 1.00 28.00  ? 156 CYS B CB  1 
ATOM   3566  S  SG  . CYS B 1 156 ? -12.659 10.816  -40.529 1.00 30.32  ? 156 CYS B SG  1 
ATOM   3567  N  N   . VAL B 1 157 ? -14.778 12.598  -38.053 1.00 27.07  ? 157 VAL B N   1 
ATOM   3568  C  CA  . VAL B 1 157 ? -15.855 12.060  -37.242 1.00 26.49  ? 157 VAL B CA  1 
ATOM   3569  C  C   . VAL B 1 157 ? -16.158 10.666  -37.761 1.00 29.41  ? 157 VAL B C   1 
ATOM   3570  O  O   . VAL B 1 157 ? -16.451 10.499  -38.947 1.00 31.40  ? 157 VAL B O   1 
ATOM   3571  C  CB  . VAL B 1 157 ? -17.103 12.946  -37.320 1.00 26.17  ? 157 VAL B CB  1 
ATOM   3572  C  CG1 . VAL B 1 157 ? -18.214 12.349  -36.445 1.00 18.93  ? 157 VAL B CG1 1 
ATOM   3573  C  CG2 . VAL B 1 157 ? -16.760 14.407  -36.942 1.00 23.54  ? 157 VAL B CG2 1 
ATOM   3574  N  N   . SER B 1 158 ? -16.079 9.662   -36.886 1.00 25.02  ? 158 SER B N   1 
ATOM   3575  C  CA  . SER B 1 158 ? -16.453 8.296   -37.251 1.00 26.52  ? 158 SER B CA  1 
ATOM   3576  C  C   . SER B 1 158 ? -17.851 8.032   -36.719 1.00 17.94  ? 158 SER B C   1 
ATOM   3577  O  O   . SER B 1 158 ? -18.030 7.765   -35.533 1.00 22.11  ? 158 SER B O   1 
ATOM   3578  C  CB  . SER B 1 158 ? -15.453 7.292   -36.698 1.00 25.28  ? 158 SER B CB  1 
ATOM   3579  O  OG  . SER B 1 158 ? -14.252 7.354   -37.445 1.00 30.46  ? 158 SER B OG  1 
ATOM   3580  N  N   . PHE B 1 159 ? -18.838 8.090   -37.603 1.00 20.01  ? 159 PHE B N   1 
ATOM   3581  C  CA  . PHE B 1 159 ? -20.217 7.814   -37.222 1.00 21.32  ? 159 PHE B CA  1 
ATOM   3582  C  C   . PHE B 1 159 ? -20.399 6.309   -37.089 1.00 21.17  ? 159 PHE B C   1 
ATOM   3583  O  O   . PHE B 1 159 ? -20.085 5.556   -38.012 1.00 23.39  ? 159 PHE B O   1 
ATOM   3584  C  CB  . PHE B 1 159 ? -21.212 8.374   -38.255 1.00 17.03  ? 159 PHE B CB  1 
ATOM   3585  C  CG  . PHE B 1 159 ? -21.272 9.893   -38.315 1.00 20.33  ? 159 PHE B CG  1 
ATOM   3586  C  CD1 . PHE B 1 159 ? -21.970 10.615  -37.349 1.00 18.08  ? 159 PHE B CD1 1 
ATOM   3587  C  CD2 . PHE B 1 159 ? -20.643 10.595  -39.342 1.00 20.09  ? 159 PHE B CD2 1 
ATOM   3588  C  CE1 . PHE B 1 159 ? -22.036 12.000  -37.399 1.00 17.46  ? 159 PHE B CE1 1 
ATOM   3589  C  CE2 . PHE B 1 159 ? -20.710 11.979  -39.395 1.00 19.27  ? 159 PHE B CE2 1 
ATOM   3590  C  CZ  . PHE B 1 159 ? -21.409 12.683  -38.414 1.00 13.83  ? 159 PHE B CZ  1 
ATOM   3591  N  N   . CYS B 1 160 ? -20.882 5.871   -35.932 1.00 21.11  ? 160 CYS B N   1 
ATOM   3592  C  CA  . CYS B 1 160 ? -21.068 4.452   -35.687 1.00 25.57  ? 160 CYS B CA  1 
ATOM   3593  C  C   . CYS B 1 160 ? -22.490 4.043   -35.342 1.00 24.91  ? 160 CYS B C   1 
ATOM   3594  O  O   . CYS B 1 160 ? -22.806 2.859   -35.484 1.00 23.54  ? 160 CYS B O   1 
ATOM   3595  C  CB  . CYS B 1 160 ? -20.133 3.976   -34.564 1.00 23.03  ? 160 CYS B CB  1 
ATOM   3596  S  SG  . CYS B 1 160 ? -20.339 4.850   -33.008 1.00 27.25  ? 160 CYS B SG  1 
ATOM   3597  N  N   . TYR B 1 161 ? -23.374 4.979   -34.976 1.00 23.35  ? 161 TYR B N   1 
ATOM   3598  C  CA  . TYR B 1 161 ? -24.644 4.586   -34.367 1.00 23.87  ? 161 TYR B CA  1 
ATOM   3599  C  C   . TYR B 1 161 ? -25.731 5.577   -34.757 1.00 25.23  ? 161 TYR B C   1 
ATOM   3600  O  O   . TYR B 1 161 ? -25.484 6.788   -34.836 1.00 20.01  ? 161 TYR B O   1 
ATOM   3601  C  CB  . TYR B 1 161 ? -24.513 4.493   -32.830 1.00 20.55  ? 161 TYR B CB  1 
ATOM   3602  C  CG  . TYR B 1 161 ? -25.801 4.137   -32.100 1.00 20.84  ? 161 TYR B CG  1 
ATOM   3603  C  CD1 . TYR B 1 161 ? -26.165 2.820   -31.884 1.00 19.63  ? 161 TYR B CD1 1 
ATOM   3604  C  CD2 . TYR B 1 161 ? -26.665 5.134   -31.644 1.00 21.12  ? 161 TYR B CD2 1 
ATOM   3605  C  CE1 . TYR B 1 161 ? -27.361 2.505   -31.223 1.00 21.80  ? 161 TYR B CE1 1 
ATOM   3606  C  CE2 . TYR B 1 161 ? -27.844 4.832   -30.979 1.00 21.07  ? 161 TYR B CE2 1 
ATOM   3607  C  CZ  . TYR B 1 161 ? -28.197 3.520   -30.772 1.00 21.35  ? 161 TYR B CZ  1 
ATOM   3608  O  OH  . TYR B 1 161 ? -29.389 3.222   -30.121 1.00 19.92  ? 161 TYR B OH  1 
ATOM   3609  N  N   . MET B 1 162 ? -26.921 5.052   -35.058 1.00 23.57  ? 162 MET B N   1 
ATOM   3610  C  CA  . MET B 1 162 ? -28.102 5.885   -35.233 1.00 20.99  ? 162 MET B CA  1 
ATOM   3611  C  C   . MET B 1 162 ? -29.224 5.256   -34.440 1.00 20.86  ? 162 MET B C   1 
ATOM   3612  O  O   . MET B 1 162 ? -29.508 4.066   -34.616 1.00 22.41  ? 162 MET B O   1 
ATOM   3613  C  CB  . MET B 1 162 ? -28.509 5.999   -36.701 1.00 23.85  ? 162 MET B CB  1 
ATOM   3614  C  CG  . MET B 1 162 ? -29.789 6.812   -36.935 1.00 22.24  ? 162 MET B CG  1 
ATOM   3615  S  SD  . MET B 1 162 ? -30.176 6.959   -38.687 1.00 24.67  ? 162 MET B SD  1 
ATOM   3616  C  CE  . MET B 1 162 ? -29.053 8.303   -39.172 1.00 18.87  ? 162 MET B CE  1 
ATOM   3617  N  N   . HIS B 1 163 ? -29.893 6.054   -33.611 1.00 20.25  ? 163 HIS B N   1 
ATOM   3618  C  CA  . HIS B 1 163 ? -30.831 5.498   -32.639 1.00 21.80  ? 163 HIS B CA  1 
ATOM   3619  C  C   . HIS B 1 163 ? -32.140 5.094   -33.300 1.00 19.97  ? 163 HIS B C   1 
ATOM   3620  O  O   . HIS B 1 163 ? -32.659 5.793   -34.181 1.00 18.71  ? 163 HIS B O   1 
ATOM   3621  C  CB  . HIS B 1 163 ? -31.113 6.499   -31.512 1.00 21.54  ? 163 HIS B CB  1 
ATOM   3622  C  CG  . HIS B 1 163 ? -32.013 5.948   -30.448 1.00 20.00  ? 163 HIS B CG  1 
ATOM   3623  N  ND1 . HIS B 1 163 ? -31.690 4.825   -29.709 1.00 19.66  ? 163 HIS B ND1 1 
ATOM   3624  C  CD2 . HIS B 1 163 ? -33.250 6.318   -30.045 1.00 21.55  ? 163 HIS B CD2 1 
ATOM   3625  C  CE1 . HIS B 1 163 ? -32.678 4.548   -28.874 1.00 19.81  ? 163 HIS B CE1 1 
ATOM   3626  N  NE2 . HIS B 1 163 ? -33.640 5.432   -29.063 1.00 20.85  ? 163 HIS B NE2 1 
ATOM   3627  N  N   . HIS B 1 164 ? -32.684 3.976   -32.855 1.00 20.82  ? 164 HIS B N   1 
ATOM   3628  C  CA  . HIS B 1 164 ? -33.929 3.427   -33.399 1.00 21.33  ? 164 HIS B CA  1 
ATOM   3629  C  C   . HIS B 1 164 ? -34.970 3.058   -32.345 1.00 23.80  ? 164 HIS B C   1 
ATOM   3630  O  O   . HIS B 1 164 ? -36.163 3.283   -32.574 1.00 20.53  ? 164 HIS B O   1 
ATOM   3631  C  CB  . HIS B 1 164 ? -33.630 2.183   -34.266 1.00 20.61  ? 164 HIS B CB  1 
ATOM   3632  C  CG  . HIS B 1 164 ? -33.251 2.492   -35.678 1.00 19.29  ? 164 HIS B CG  1 
ATOM   3633  N  ND1 . HIS B 1 164 ? -32.049 3.077   -36.018 1.00 23.24  ? 164 HIS B ND1 1 
ATOM   3634  C  CD2 . HIS B 1 164 ? -33.897 2.259   -36.844 1.00 23.90  ? 164 HIS B CD2 1 
ATOM   3635  C  CE1 . HIS B 1 164 ? -31.986 3.221   -37.331 1.00 24.21  ? 164 HIS B CE1 1 
ATOM   3636  N  NE2 . HIS B 1 164 ? -33.096 2.736   -37.856 1.00 26.63  ? 164 HIS B NE2 1 
ATOM   3637  N  N   . MET B 1 165 ? -34.569 2.469   -31.218 1.00 22.08  ? 165 MET B N   1 
ATOM   3638  C  CA  . MET B 1 165 ? -35.566 1.837   -30.355 1.00 27.88  ? 165 MET B CA  1 
ATOM   3639  C  C   . MET B 1 165 ? -35.073 1.670   -28.924 1.00 23.86  ? 165 MET B C   1 
ATOM   3640  O  O   . MET B 1 165 ? -33.873 1.618   -28.644 1.00 21.27  ? 165 MET B O   1 
ATOM   3641  C  CB  . MET B 1 165 ? -35.993 0.462   -30.904 1.00 28.20  ? 165 MET B CB  1 
ATOM   3642  C  CG  . MET B 1 165 ? -34.853 -0.504  -31.146 1.00 25.73  ? 165 MET B CG  1 
ATOM   3643  S  SD  . MET B 1 165 ? -35.381 -2.101  -31.845 1.00 34.14  ? 165 MET B SD  1 
ATOM   3644  C  CE  . MET B 1 165 ? -36.494 -2.697  -30.570 1.00 38.33  ? 165 MET B CE  1 
ATOM   3645  N  N   . GLU B 1 166 ? -36.046 1.565   -28.029 1.00 27.31  ? 166 GLU B N   1 
ATOM   3646  C  CA  . GLU B 1 166 ? -35.855 1.251   -26.623 1.00 30.23  ? 166 GLU B CA  1 
ATOM   3647  C  C   . GLU B 1 166 ? -36.347 -0.170  -26.385 1.00 30.96  ? 166 GLU B C   1 
ATOM   3648  O  O   . GLU B 1 166 ? -37.255 -0.645  -27.070 1.00 26.18  ? 166 GLU B O   1 
ATOM   3649  C  CB  . GLU B 1 166 ? -36.615 2.222   -25.723 1.00 26.20  ? 166 GLU B CB  1 
ATOM   3650  C  CG  . GLU B 1 166 ? -38.111 2.116   -25.928 1.00 35.99  ? 166 GLU B CG  1 
ATOM   3651  C  CD  . GLU B 1 166 ? -38.907 3.119   -25.123 1.00 41.58  ? 166 GLU B CD  1 
ATOM   3652  O  OE1 . GLU B 1 166 ? -38.317 3.778   -24.237 1.00 38.73  ? 166 GLU B OE1 1 
ATOM   3653  O  OE2 . GLU B 1 166 ? -40.131 3.237   -25.380 1.00 45.30  ? 166 GLU B OE2 1 
ATOM   3654  N  N   . LEU B 1 167 ? -35.679 -0.872  -25.474 1.00 31.91  ? 167 LEU B N   1 
ATOM   3655  C  CA  . LEU B 1 167 ? -35.981 -2.253  -25.136 1.00 31.43  ? 167 LEU B CA  1 
ATOM   3656  C  C   . LEU B 1 167 ? -36.508 -2.348  -23.698 1.00 35.64  ? 167 LEU B C   1 
ATOM   3657  O  O   . LEU B 1 167 ? -36.339 -1.410  -22.906 1.00 26.65  ? 167 LEU B O   1 
ATOM   3658  C  CB  . LEU B 1 167 ? -34.711 -3.099  -25.333 1.00 23.23  ? 167 LEU B CB  1 
ATOM   3659  C  CG  . LEU B 1 167 ? -34.356 -3.268  -26.817 1.00 28.51  ? 167 LEU B CG  1 
ATOM   3660  C  CD1 . LEU B 1 167 ? -32.920 -3.741  -27.044 1.00 26.30  ? 167 LEU B CD1 1 
ATOM   3661  C  CD2 . LEU B 1 167 ? -35.329 -4.224  -27.516 1.00 29.88  ? 167 LEU B CD2 1 
ATOM   3662  N  N   . PRO B 1 168 ? -37.124 -3.486  -23.315 1.00 33.66  ? 168 PRO B N   1 
ATOM   3663  C  CA  . PRO B 1 168 ? -37.820 -3.556  -22.011 1.00 33.40  ? 168 PRO B CA  1 
ATOM   3664  C  C   . PRO B 1 168 ? -37.020 -3.114  -20.799 1.00 37.05  ? 168 PRO B C   1 
ATOM   3665  O  O   . PRO B 1 168 ? -37.593 -2.499  -19.891 1.00 45.96  ? 168 PRO B O   1 
ATOM   3666  C  CB  . PRO B 1 168 ? -38.183 -5.037  -21.904 1.00 34.69  ? 168 PRO B CB  1 
ATOM   3667  C  CG  . PRO B 1 168 ? -38.366 -5.465  -23.299 1.00 34.35  ? 168 PRO B CG  1 
ATOM   3668  C  CD  . PRO B 1 168 ? -37.316 -4.726  -24.084 1.00 34.06  ? 168 PRO B CD  1 
ATOM   3669  N  N   . THR B 1 169 ? -35.729 -3.414  -20.733 1.00 37.04  ? 169 THR B N   1 
ATOM   3670  C  CA  . THR B 1 169 ? -34.962 -3.094  -19.535 1.00 38.92  ? 169 THR B CA  1 
ATOM   3671  C  C   . THR B 1 169 ? -34.463 -1.638  -19.493 1.00 39.11  ? 169 THR B C   1 
ATOM   3672  O  O   . THR B 1 169 ? -33.562 -1.317  -18.706 1.00 38.61  ? 169 THR B O   1 
ATOM   3673  C  CB  . THR B 1 169 ? -33.797 -4.077  -19.398 1.00 46.22  ? 169 THR B CB  1 
ATOM   3674  O  OG1 . THR B 1 169 ? -33.025 -4.082  -20.608 1.00 37.13  ? 169 THR B OG1 1 
ATOM   3675  C  CG2 . THR B 1 169 ? -34.320 -5.493  -19.113 1.00 39.87  ? 169 THR B CG2 1 
ATOM   3676  N  N   . GLY B 1 170 ? -35.043 -0.741  -20.281 1.00 38.70  ? 170 GLY B N   1 
ATOM   3677  C  CA  . GLY B 1 170 ? -34.568 0.629   -20.277 1.00 36.77  ? 170 GLY B CA  1 
ATOM   3678  C  C   . GLY B 1 170 ? -33.249 0.840   -20.984 1.00 28.93  ? 170 GLY B C   1 
ATOM   3679  O  O   . GLY B 1 170 ? -32.530 1.780   -20.663 1.00 33.23  ? 170 GLY B O   1 
ATOM   3680  N  N   . VAL B 1 171 ? -32.894 -0.037  -21.915 1.00 29.29  ? 171 VAL B N   1 
ATOM   3681  C  CA  . VAL B 1 171 ? -31.693 0.107   -22.720 1.00 24.77  ? 171 VAL B CA  1 
ATOM   3682  C  C   . VAL B 1 171 ? -32.154 0.364   -24.148 1.00 25.87  ? 171 VAL B C   1 
ATOM   3683  O  O   . VAL B 1 171 ? -33.360 0.367   -24.434 1.00 24.72  ? 171 VAL B O   1 
ATOM   3684  C  CB  . VAL B 1 171 ? -30.789 -1.145  -22.629 1.00 25.87  ? 171 VAL B CB  1 
ATOM   3685  C  CG1 . VAL B 1 171 ? -30.422 -1.448  -21.152 1.00 25.18  ? 171 VAL B CG1 1 
ATOM   3686  C  CG2 . VAL B 1 171 ? -31.433 -2.334  -23.292 1.00 18.09  ? 171 VAL B CG2 1 
ATOM   3687  N  N   . HIS B 1 172 ? -31.202 0.573   -25.057 1.00 22.43  ? 172 HIS B N   1 
ATOM   3688  C  CA  . HIS B 1 172 ? -31.505 1.121   -26.364 1.00 22.69  ? 172 HIS B CA  1 
ATOM   3689  C  C   . HIS B 1 172 ? -30.775 0.332   -27.442 1.00 21.26  ? 172 HIS B C   1 
ATOM   3690  O  O   . HIS B 1 172 ? -29.730 -0.276  -27.192 1.00 20.61  ? 172 HIS B O   1 
ATOM   3691  C  CB  . HIS B 1 172 ? -31.146 2.616   -26.395 1.00 22.08  ? 172 HIS B CB  1 
ATOM   3692  C  CG  . HIS B 1 172 ? -31.902 3.420   -25.380 1.00 25.54  ? 172 HIS B CG  1 
ATOM   3693  N  ND1 . HIS B 1 172 ? -31.342 3.857   -24.198 1.00 26.83  ? 172 HIS B ND1 1 
ATOM   3694  C  CD2 . HIS B 1 172 ? -33.189 3.844   -25.363 1.00 23.67  ? 172 HIS B CD2 1 
ATOM   3695  C  CE1 . HIS B 1 172 ? -32.246 4.530   -23.505 1.00 26.65  ? 172 HIS B CE1 1 
ATOM   3696  N  NE2 . HIS B 1 172 ? -33.376 4.534   -24.188 1.00 22.88  ? 172 HIS B NE2 1 
ATOM   3697  N  N   . ALA B 1 173 ? -31.334 0.358   -28.649 1.00 19.45  ? 173 ALA B N   1 
ATOM   3698  C  CA  . ALA B 1 173 ? -30.798 -0.386  -29.783 1.00 25.39  ? 173 ALA B CA  1 
ATOM   3699  C  C   . ALA B 1 173 ? -30.843 0.480   -31.045 1.00 22.99  ? 173 ALA B C   1 
ATOM   3700  O  O   . ALA B 1 173 ? -31.745 1.304   -31.222 1.00 20.12  ? 173 ALA B O   1 
ATOM   3701  C  CB  . ALA B 1 173 ? -31.574 -1.697  -30.002 1.00 23.48  ? 173 ALA B CB  1 
ATOM   3702  N  N   . GLY B 1 174 ? -29.858 0.292   -31.917 1.00 18.83  ? 174 GLY B N   1 
ATOM   3703  C  CA  . GLY B 1 174 ? -29.836 1.024   -33.159 1.00 19.04  ? 174 GLY B CA  1 
ATOM   3704  C  C   . GLY B 1 174 ? -29.005 0.312   -34.206 1.00 22.59  ? 174 GLY B C   1 
ATOM   3705  O  O   . GLY B 1 174 ? -28.603 -0.837  -34.024 1.00 22.26  ? 174 GLY B O   1 
ATOM   3706  N  N   . THR B 1 175 ? -28.735 1.032   -35.300 1.00 20.82  ? 175 THR B N   1 
ATOM   3707  C  CA  . THR B 1 175 ? -28.023 0.554   -36.480 1.00 21.25  ? 175 THR B CA  1 
ATOM   3708  C  C   . THR B 1 175 ? -26.698 1.289   -36.651 1.00 25.92  ? 175 THR B C   1 
ATOM   3709  O  O   . THR B 1 175 ? -26.448 2.346   -36.049 1.00 23.47  ? 175 THR B O   1 
ATOM   3710  C  CB  . THR B 1 175 ? -28.853 0.766   -37.760 1.00 28.23  ? 175 THR B CB  1 
ATOM   3711  O  OG1 . THR B 1 175 ? -29.017 2.186   -38.017 1.00 23.27  ? 175 THR B OG1 1 
ATOM   3712  C  CG2 . THR B 1 175 ? -30.219 0.047   -37.686 1.00 25.32  ? 175 THR B CG2 1 
ATOM   3713  N  N   . ASP B 1 176 ? -25.843 0.742   -37.512 1.00 21.08  ? 176 ASP B N   1 
ATOM   3714  C  CA  . ASP B 1 176 ? -24.775 1.592   -38.027 1.00 24.58  ? 176 ASP B CA  1 
ATOM   3715  C  C   . ASP B 1 176 ? -25.364 2.561   -39.062 1.00 25.07  ? 176 ASP B C   1 
ATOM   3716  O  O   . ASP B 1 176 ? -26.570 2.569   -39.329 1.00 26.72  ? 176 ASP B O   1 
ATOM   3717  C  CB  . ASP B 1 176 ? -23.622 0.735   -38.574 1.00 24.42  ? 176 ASP B CB  1 
ATOM   3718  C  CG  . ASP B 1 176 ? -24.052 -0.223  -39.704 1.00 26.69  ? 176 ASP B CG  1 
ATOM   3719  O  OD1 . ASP B 1 176 ? -25.061 0.042   -40.420 1.00 23.49  ? 176 ASP B OD1 1 
ATOM   3720  O  OD2 . ASP B 1 176 ? -23.366 -1.271  -39.860 1.00 25.62  ? 176 ASP B OD2 1 
ATOM   3721  N  N   . LEU B 1 177 ? -24.509 3.370   -39.687 1.00 25.03  ? 177 LEU B N   1 
ATOM   3722  C  CA  . LEU B 1 177 ? -24.998 4.327   -40.669 1.00 20.89  ? 177 LEU B CA  1 
ATOM   3723  C  C   . LEU B 1 177 ? -25.235 3.691   -42.030 1.00 27.80  ? 177 LEU B C   1 
ATOM   3724  O  O   . LEU B 1 177 ? -25.688 4.384   -42.951 1.00 30.46  ? 177 LEU B O   1 
ATOM   3725  C  CB  . LEU B 1 177 ? -24.017 5.496   -40.809 1.00 22.40  ? 177 LEU B CB  1 
ATOM   3726  C  CG  . LEU B 1 177 ? -24.258 6.749   -39.951 1.00 21.58  ? 177 LEU B CG  1 
ATOM   3727  C  CD1 . LEU B 1 177 ? -25.531 7.417   -40.399 1.00 12.42  ? 177 LEU B CD1 1 
ATOM   3728  C  CD2 . LEU B 1 177 ? -24.297 6.434   -38.458 1.00 15.70  ? 177 LEU B CD2 1 
ATOM   3729  N  N   . GLU B 1 178 ? -24.966 2.392   -42.174 1.00 26.88  ? 178 GLU B N   1 
ATOM   3730  C  CA  . GLU B 1 178 ? -25.444 1.619   -43.313 1.00 29.20  ? 178 GLU B CA  1 
ATOM   3731  C  C   . GLU B 1 178 ? -26.802 0.982   -43.060 1.00 28.63  ? 178 GLU B C   1 
ATOM   3732  O  O   . GLU B 1 178 ? -27.233 0.149   -43.874 1.00 27.86  ? 178 GLU B O   1 
ATOM   3733  C  CB  . GLU B 1 178 ? -24.461 0.505   -43.662 1.00 27.23  ? 178 GLU B CB  1 
ATOM   3734  C  CG  . GLU B 1 178 ? -23.014 0.898   -43.586 1.00 36.44  ? 178 GLU B CG  1 
ATOM   3735  C  CD  . GLU B 1 178 ? -22.387 0.933   -44.955 1.00 40.35  ? 178 GLU B CD  1 
ATOM   3736  O  OE1 . GLU B 1 178 ? -23.137 1.143   -45.922 1.00 37.97  ? 178 GLU B OE1 1 
ATOM   3737  O  OE2 . GLU B 1 178 ? -21.161 0.695   -45.066 1.00 52.08  ? 178 GLU B OE2 1 
ATOM   3738  N  N   . GLY B 1 179 ? -27.424 1.257   -41.909 1.00 21.90  ? 179 GLY B N   1 
ATOM   3739  C  CA  . GLY B 1 179 ? -28.751 0.751   -41.617 1.00 21.29  ? 179 GLY B CA  1 
ATOM   3740  C  C   . GLY B 1 179 ? -28.816 -0.648  -41.051 1.00 23.80  ? 179 GLY B C   1 
ATOM   3741  O  O   . GLY B 1 179 ? -29.900 -1.234  -41.029 1.00 23.61  ? 179 GLY B O   1 
ATOM   3742  N  N   . ASN B 1 180 ? -27.694 -1.223  -40.630 1.00 24.60  ? 180 ASN B N   1 
ATOM   3743  C  CA  . ASN B 1 180 ? -27.666 -2.567  -40.077 1.00 21.97  ? 180 ASN B CA  1 
ATOM   3744  C  C   . ASN B 1 180 ? -27.694 -2.516  -38.560 1.00 23.94  ? 180 ASN B C   1 
ATOM   3745  O  O   . ASN B 1 180 ? -26.810 -1.924  -37.937 1.00 24.98  ? 180 ASN B O   1 
ATOM   3746  C  CB  . ASN B 1 180 ? -26.434 -3.314  -40.558 1.00 25.69  ? 180 ASN B CB  1 
ATOM   3747  C  CG  . ASN B 1 180 ? -26.372 -3.386  -42.057 1.00 26.07  ? 180 ASN B CG  1 
ATOM   3748  O  OD1 . ASN B 1 180 ? -27.183 -4.053  -42.686 1.00 24.51  ? 180 ASN B OD1 1 
ATOM   3749  N  ND2 . ASN B 1 180 ? -25.425 -2.682  -42.638 1.00 26.56  ? 180 ASN B ND2 1 
ATOM   3750  N  N   . PHE B 1 181 ? -28.701 -3.147  -37.979 1.00 22.91  ? 181 PHE B N   1 
ATOM   3751  C  CA  . PHE B 1 181 ? -28.825 -3.206  -36.538 1.00 20.89  ? 181 PHE B CA  1 
ATOM   3752  C  C   . PHE B 1 181 ? -27.589 -3.839  -35.915 1.00 25.00  ? 181 PHE B C   1 
ATOM   3753  O  O   . PHE B 1 181 ? -26.963 -4.742  -36.487 1.00 18.31  ? 181 PHE B O   1 
ATOM   3754  C  CB  . PHE B 1 181 ? -30.077 -4.002  -36.153 1.00 22.36  ? 181 PHE B CB  1 
ATOM   3755  C  CG  . PHE B 1 181 ? -31.269 -3.144  -35.874 1.00 21.73  ? 181 PHE B CG  1 
ATOM   3756  C  CD1 . PHE B 1 181 ? -31.448 -2.562  -34.622 1.00 26.06  ? 181 PHE B CD1 1 
ATOM   3757  C  CD2 . PHE B 1 181 ? -32.203 -2.900  -36.851 1.00 22.40  ? 181 PHE B CD2 1 
ATOM   3758  C  CE1 . PHE B 1 181 ? -32.550 -1.745  -34.360 1.00 23.38  ? 181 PHE B CE1 1 
ATOM   3759  C  CE2 . PHE B 1 181 ? -33.306 -2.086  -36.590 1.00 25.63  ? 181 PHE B CE2 1 
ATOM   3760  C  CZ  . PHE B 1 181 ? -33.474 -1.513  -35.347 1.00 20.49  ? 181 PHE B CZ  1 
ATOM   3761  N  N   . TYR B 1 182 ? -27.209 -3.313  -34.757 1.00 21.48  ? 182 TYR B N   1 
ATOM   3762  C  CA  . TYR B 1 182 ? -26.348 -4.038  -33.846 1.00 23.04  ? 182 TYR B CA  1 
ATOM   3763  C  C   . TYR B 1 182 ? -27.223 -5.042  -33.108 1.00 27.86  ? 182 TYR B C   1 
ATOM   3764  O  O   . TYR B 1 182 ? -28.218 -4.662  -32.480 1.00 26.67  ? 182 TYR B O   1 
ATOM   3765  C  CB  . TYR B 1 182 ? -25.655 -3.075  -32.882 1.00 21.66  ? 182 TYR B CB  1 
ATOM   3766  C  CG  . TYR B 1 182 ? -24.634 -2.158  -33.542 1.00 22.09  ? 182 TYR B CG  1 
ATOM   3767  C  CD1 . TYR B 1 182 ? -23.353 -2.611  -33.846 1.00 21.41  ? 182 TYR B CD1 1 
ATOM   3768  C  CD2 . TYR B 1 182 ? -24.953 -0.850  -33.867 1.00 20.18  ? 182 TYR B CD2 1 
ATOM   3769  C  CE1 . TYR B 1 182 ? -22.407 -1.781  -34.448 1.00 21.67  ? 182 TYR B CE1 1 
ATOM   3770  C  CE2 . TYR B 1 182 ? -24.023 -0.005  -34.473 1.00 21.72  ? 182 TYR B CE2 1 
ATOM   3771  C  CZ  . TYR B 1 182 ? -22.751 -0.473  -34.761 1.00 23.20  ? 182 TYR B CZ  1 
ATOM   3772  O  OH  . TYR B 1 182 ? -21.830 0.359   -35.357 1.00 18.08  ? 182 TYR B OH  1 
ATOM   3773  N  N   . GLY B 1 183 ? -26.901 -6.319  -33.234 1.00 29.00  ? 183 GLY B N   1 
ATOM   3774  C  CA  . GLY B 1 183 ? -27.603 -7.350  -32.503 1.00 27.80  ? 183 GLY B CA  1 
ATOM   3775  C  C   . GLY B 1 183 ? -28.837 -7.840  -33.217 1.00 25.72  ? 183 GLY B C   1 
ATOM   3776  O  O   . GLY B 1 183 ? -29.168 -7.391  -34.318 1.00 32.57  ? 183 GLY B O   1 
ATOM   3777  N  N   . PRO B 1 184 ? -29.544 -8.774  -32.598 1.00 30.26  ? 184 PRO B N   1 
ATOM   3778  C  CA  . PRO B 1 184 ? -30.688 -9.444  -33.242 1.00 31.45  ? 184 PRO B CA  1 
ATOM   3779  C  C   . PRO B 1 184 ? -31.978 -8.637  -33.134 1.00 32.19  ? 184 PRO B C   1 
ATOM   3780  O  O   . PRO B 1 184 ? -32.994 -9.105  -32.615 1.00 40.56  ? 184 PRO B O   1 
ATOM   3781  C  CB  . PRO B 1 184 ? -30.762 -10.768 -32.471 1.00 23.21  ? 184 PRO B CB  1 
ATOM   3782  C  CG  . PRO B 1 184 ? -30.336 -10.404 -31.103 1.00 26.97  ? 184 PRO B CG  1 
ATOM   3783  C  CD  . PRO B 1 184 ? -29.306 -9.294  -31.240 1.00 30.06  ? 184 PRO B CD  1 
ATOM   3784  N  N   . PHE B 1 185 ? -31.937 -7.401  -33.603 1.00 29.51  ? 185 PHE B N   1 
ATOM   3785  C  CA  . PHE B 1 185 ? -33.074 -6.510  -33.487 1.00 30.82  ? 185 PHE B CA  1 
ATOM   3786  C  C   . PHE B 1 185 ? -33.574 -6.143  -34.873 1.00 29.49  ? 185 PHE B C   1 
ATOM   3787  O  O   . PHE B 1 185 ? -32.860 -6.288  -35.867 1.00 35.98  ? 185 PHE B O   1 
ATOM   3788  C  CB  . PHE B 1 185 ? -32.709 -5.253  -32.660 1.00 34.96  ? 185 PHE B CB  1 
ATOM   3789  C  CG  . PHE B 1 185 ? -32.146 -5.583  -31.307 1.00 35.60  ? 185 PHE B CG  1 
ATOM   3790  C  CD1 . PHE B 1 185 ? -32.933 -6.223  -30.358 1.00 32.90  ? 185 PHE B CD1 1 
ATOM   3791  C  CD2 . PHE B 1 185 ? -30.824 -5.316  -30.998 1.00 35.64  ? 185 PHE B CD2 1 
ATOM   3792  C  CE1 . PHE B 1 185 ? -32.411 -6.564  -29.121 1.00 32.43  ? 185 PHE B CE1 1 
ATOM   3793  C  CE2 . PHE B 1 185 ? -30.296 -5.662  -29.757 1.00 27.94  ? 185 PHE B CE2 1 
ATOM   3794  C  CZ  . PHE B 1 185 ? -31.086 -6.285  -28.827 1.00 27.48  ? 185 PHE B CZ  1 
ATOM   3795  N  N   . VAL B 1 186 ? -34.853 -5.788  -34.940 1.00 28.46  ? 186 VAL B N   1 
ATOM   3796  C  CA  . VAL B 1 186 ? -35.495 -5.336  -36.162 1.00 30.97  ? 186 VAL B CA  1 
ATOM   3797  C  C   . VAL B 1 186 ? -36.342 -4.124  -35.815 1.00 30.04  ? 186 VAL B C   1 
ATOM   3798  O  O   . VAL B 1 186 ? -36.761 -3.947  -34.670 1.00 27.34  ? 186 VAL B O   1 
ATOM   3799  C  CB  . VAL B 1 186 ? -36.356 -6.435  -36.820 1.00 36.94  ? 186 VAL B CB  1 
ATOM   3800  C  CG1 . VAL B 1 186 ? -35.465 -7.568  -37.319 1.00 29.68  ? 186 VAL B CG1 1 
ATOM   3801  C  CG2 . VAL B 1 186 ? -37.430 -6.939  -35.837 1.00 29.01  ? 186 VAL B CG2 1 
ATOM   3802  N  N   . ASP B 1 187 ? -36.588 -3.283  -36.827 1.00 28.84  ? 187 ASP B N   1 
ATOM   3803  C  CA  . ASP B 1 187 ? -37.361 -2.049  -36.648 1.00 26.85  ? 187 ASP B CA  1 
ATOM   3804  C  C   . ASP B 1 187 ? -38.847 -2.317  -36.886 1.00 33.16  ? 187 ASP B C   1 
ATOM   3805  O  O   . ASP B 1 187 ? -39.470 -1.841  -37.834 1.00 34.91  ? 187 ASP B O   1 
ATOM   3806  C  CB  . ASP B 1 187 ? -36.842 -0.929  -37.546 1.00 29.73  ? 187 ASP B CB  1 
ATOM   3807  C  CG  . ASP B 1 187 ? -36.751 -1.317  -39.007 1.00 31.88  ? 187 ASP B CG  1 
ATOM   3808  O  OD1 . ASP B 1 187 ? -36.994 -2.505  -39.363 1.00 36.33  ? 187 ASP B OD1 1 
ATOM   3809  O  OD2 . ASP B 1 187 ? -36.458 -0.402  -39.809 1.00 27.67  ? 187 ASP B OD2 1 
ATOM   3810  N  N   . ARG B 1 188 ? -39.413 -3.102  -35.982 1.00 38.90  ? 188 ARG B N   1 
ATOM   3811  C  CA  . ARG B 1 188 ? -40.838 -3.375  -35.963 1.00 47.14  ? 188 ARG B CA  1 
ATOM   3812  C  C   . ARG B 1 188 ? -41.328 -3.210  -34.537 1.00 50.93  ? 188 ARG B C   1 
ATOM   3813  O  O   . ARG B 1 188 ? -40.534 -3.178  -33.596 1.00 54.72  ? 188 ARG B O   1 
ATOM   3814  C  CB  . ARG B 1 188 ? -41.162 -4.780  -36.488 1.00 47.34  ? 188 ARG B CB  1 
ATOM   3815  C  CG  . ARG B 1 188 ? -40.554 -5.085  -37.851 1.00 47.50  ? 188 ARG B CG  1 
ATOM   3816  C  CD  . ARG B 1 188 ? -41.235 -6.282  -38.502 1.00 53.10  ? 188 ARG B CD  1 
ATOM   3817  N  NE  . ARG B 1 188 ? -40.784 -7.537  -37.916 1.00 51.66  ? 188 ARG B NE  1 
ATOM   3818  C  CZ  . ARG B 1 188 ? -39.820 -8.301  -38.419 1.00 55.55  ? 188 ARG B CZ  1 
ATOM   3819  N  NH1 . ARG B 1 188 ? -39.159 -7.954  -39.512 1.00 53.67  ? 188 ARG B NH1 1 
ATOM   3820  N  NH2 . ARG B 1 188 ? -39.486 -9.423  -37.789 1.00 47.31  ? 188 ARG B NH2 1 
ATOM   3821  N  N   . GLN B 1 189 ? -42.645 -3.069  -34.376 1.00 65.97  ? 189 GLN B N   1 
ATOM   3822  C  CA  . GLN B 1 189 ? -43.226 -3.003  -33.035 1.00 60.98  ? 189 GLN B CA  1 
ATOM   3823  C  C   . GLN B 1 189 ? -43.634 -4.419  -32.646 1.00 60.60  ? 189 GLN B C   1 
ATOM   3824  O  O   . GLN B 1 189 ? -44.800 -4.806  -32.684 1.00 74.67  ? 189 GLN B O   1 
ATOM   3825  C  CB  . GLN B 1 189 ? -44.400 -2.031  -32.980 1.00 69.47  ? 189 GLN B CB  1 
ATOM   3826  C  CG  . GLN B 1 189 ? -44.986 -1.818  -31.573 1.00 65.49  ? 189 GLN B CG  1 
ATOM   3827  C  CD  . GLN B 1 189 ? -45.921 -0.598  -31.492 1.00 78.10  ? 189 GLN B CD  1 
ATOM   3828  O  OE1 . GLN B 1 189 ? -46.063 0.164   -32.458 1.00 75.58  ? 189 GLN B OE1 1 
ATOM   3829  N  NE2 . GLN B 1 189 ? -46.525 -0.389  -30.318 1.00 74.95  ? 189 GLN B NE2 1 
ATOM   3830  N  N   . THR B 1 190 ? -42.632 -5.212  -32.288 1.00 59.04  ? 190 THR B N   1 
ATOM   3831  C  CA  . THR B 1 190 ? -42.854 -6.549  -31.774 1.00 52.28  ? 190 THR B CA  1 
ATOM   3832  C  C   . THR B 1 190 ? -42.036 -6.656  -30.501 1.00 52.12  ? 190 THR B C   1 
ATOM   3833  O  O   . THR B 1 190 ? -41.119 -5.865  -30.263 1.00 54.93  ? 190 THR B O   1 
ATOM   3834  C  CB  . THR B 1 190 ? -42.459 -7.669  -32.769 1.00 54.98  ? 190 THR B CB  1 
ATOM   3835  O  OG1 . THR B 1 190 ? -41.037 -7.698  -32.965 1.00 55.57  ? 190 THR B OG1 1 
ATOM   3836  C  CG2 . THR B 1 190 ? -43.133 -7.441  -34.113 1.00 61.00  ? 190 THR B CG2 1 
ATOM   3837  N  N   . ALA B 1 191 ? -42.370 -7.652  -29.693 1.00 51.71  ? 191 ALA B N   1 
ATOM   3838  C  CA  . ALA B 1 191 ? -41.696 -7.849  -28.422 1.00 45.99  ? 191 ALA B CA  1 
ATOM   3839  C  C   . ALA B 1 191 ? -40.275 -8.334  -28.671 1.00 50.56  ? 191 ALA B C   1 
ATOM   3840  O  O   . ALA B 1 191 ? -40.071 -9.427  -29.216 1.00 49.87  ? 191 ALA B O   1 
ATOM   3841  C  CB  . ALA B 1 191 ? -42.473 -8.844  -27.566 1.00 48.23  ? 191 ALA B CB  1 
ATOM   3842  N  N   . GLN B 1 192 ? -39.291 -7.524  -28.279 1.00 38.96  ? 192 GLN B N   1 
ATOM   3843  C  CA  . GLN B 1 192 ? -37.888 -7.882  -28.432 1.00 40.02  ? 192 GLN B CA  1 
ATOM   3844  C  C   . GLN B 1 192 ? -37.201 -7.731  -27.085 1.00 37.65  ? 192 GLN B C   1 
ATOM   3845  O  O   . GLN B 1 192 ? -37.446 -6.766  -26.363 1.00 40.60  ? 192 GLN B O   1 
ATOM   3846  C  CB  . GLN B 1 192 ? -37.202 -7.006  -29.485 1.00 36.68  ? 192 GLN B CB  1 
ATOM   3847  C  CG  . GLN B 1 192 ? -38.006 -6.885  -30.769 1.00 34.98  ? 192 GLN B CG  1 
ATOM   3848  C  CD  . GLN B 1 192 ? -37.310 -6.089  -31.855 1.00 35.32  ? 192 GLN B CD  1 
ATOM   3849  O  OE1 . GLN B 1 192 ? -36.185 -6.400  -32.245 1.00 33.58  ? 192 GLN B OE1 1 
ATOM   3850  N  NE2 . GLN B 1 192 ? -37.987 -5.069  -32.363 1.00 30.11  ? 192 GLN B NE2 1 
ATOM   3851  N  N   . ALA B 1 193 ? -36.359 -8.694  -26.741 1.00 39.83  ? 193 ALA B N   1 
ATOM   3852  C  CA  . ALA B 1 193 ? -35.655 -8.695  -25.469 1.00 38.48  ? 193 ALA B CA  1 
ATOM   3853  C  C   . ALA B 1 193 ? -34.166 -8.572  -25.748 1.00 39.00  ? 193 ALA B C   1 
ATOM   3854  O  O   . ALA B 1 193 ? -33.655 -9.173  -26.700 1.00 37.82  ? 193 ALA B O   1 
ATOM   3855  C  CB  . ALA B 1 193 ? -35.955 -9.966  -24.655 1.00 27.72  ? 193 ALA B CB  1 
ATOM   3856  N  N   . ALA B 1 194 ? -33.481 -7.772  -24.930 1.00 29.03  ? 194 ALA B N   1 
ATOM   3857  C  CA  . ALA B 1 194 ? -32.070 -7.503  -25.173 1.00 34.21  ? 194 ALA B CA  1 
ATOM   3858  C  C   . ALA B 1 194 ? -31.254 -8.790  -25.258 1.00 42.64  ? 194 ALA B C   1 
ATOM   3859  O  O   . ALA B 1 194 ? -30.633 -9.089  -26.286 1.00 49.45  ? 194 ALA B O   1 
ATOM   3860  C  CB  . ALA B 1 194 ? -31.521 -6.596  -24.071 1.00 36.95  ? 194 ALA B CB  1 
ATOM   3861  N  N   . GLY B 1 195 ? -31.272 -9.579  -24.205 1.00 29.96  ? 195 GLY B N   1 
ATOM   3862  C  CA  . GLY B 1 195 ? -30.293 -10.634 -24.071 1.00 38.61  ? 195 GLY B CA  1 
ATOM   3863  C  C   . GLY B 1 195 ? -29.329 -10.351 -22.930 1.00 38.63  ? 195 GLY B C   1 
ATOM   3864  O  O   . GLY B 1 195 ? -29.199 -9.223  -22.441 1.00 34.71  ? 195 GLY B O   1 
ATOM   3865  N  N   . THR B 1 196 ? -28.613 -11.392 -22.529 1.00 39.11  ? 196 THR B N   1 
ATOM   3866  C  CA  . THR B 1 196 ? -27.805 -11.306 -21.325 1.00 34.50  ? 196 THR B CA  1 
ATOM   3867  C  C   . THR B 1 196 ? -26.461 -10.651 -21.608 1.00 30.01  ? 196 THR B C   1 
ATOM   3868  O  O   . THR B 1 196 ? -25.842 -10.883 -22.646 1.00 31.65  ? 196 THR B O   1 
ATOM   3869  C  CB  . THR B 1 196 ? -27.611 -12.696 -20.719 1.00 30.74  ? 196 THR B CB  1 
ATOM   3870  O  OG1 . THR B 1 196 ? -27.004 -12.562 -19.430 1.00 36.77  ? 196 THR B OG1 1 
ATOM   3871  C  CG2 . THR B 1 196 ? -26.735 -13.551 -21.606 1.00 28.28  ? 196 THR B CG2 1 
ATOM   3872  N  N   . ASP B 1 197 ? -26.050 -9.795  -20.682 1.00 35.39  ? 197 ASP B N   1 
ATOM   3873  C  CA  . ASP B 1 197 ? -24.815 -8.999  -20.875 1.00 33.48  ? 197 ASP B CA  1 
ATOM   3874  C  C   . ASP B 1 197 ? -23.731 -9.353  -19.855 1.00 30.92  ? 197 ASP B C   1 
ATOM   3875  O  O   . ASP B 1 197 ? -24.045 -9.919  -18.813 1.00 32.57  ? 197 ASP B O   1 
ATOM   3876  C  CB  . ASP B 1 197 ? -25.137 -7.506  -20.789 1.00 30.85  ? 197 ASP B CB  1 
ATOM   3877  C  CG  . ASP B 1 197 ? -24.100 -6.573  -21.384 1.00 30.76  ? 197 ASP B CG  1 
ATOM   3878  O  OD1 . ASP B 1 197 ? -23.444 -6.961  -22.360 1.00 30.49  ? 197 ASP B OD1 1 
ATOM   3879  O  OD2 . ASP B 1 197 ? -23.978 -5.457  -20.866 1.00 36.21  ? 197 ASP B OD2 1 
ATOM   3880  N  N   . THR B 1 198 ? -22.502 -8.985  -20.165 1.00 32.44  ? 198 THR B N   1 
ATOM   3881  C  CA  . THR B 1 198 ? -21.354 -9.275  -19.299 1.00 28.12  ? 198 THR B CA  1 
ATOM   3882  C  C   . THR B 1 198 ? -20.616 -7.984  -19.001 1.00 25.27  ? 198 THR B C   1 
ATOM   3883  O  O   . THR B 1 198 ? -20.723 -7.056  -19.792 1.00 26.31  ? 198 THR B O   1 
ATOM   3884  C  CB  . THR B 1 198 ? -20.358 -10.190 -20.016 1.00 27.96  ? 198 THR B CB  1 
ATOM   3885  O  OG1 . THR B 1 198 ? -20.248 -9.773  -21.374 1.00 27.08  ? 198 THR B OG1 1 
ATOM   3886  C  CG2 . THR B 1 198 ? -20.755 -11.647 -19.952 1.00 30.84  ? 198 THR B CG2 1 
ATOM   3887  N  N   . THR B 1 199 ? -19.895 -7.958  -17.895 1.00 23.16  ? 199 THR B N   1 
ATOM   3888  C  CA  . THR B 1 199 ? -19.048 -6.811  -17.619 1.00 29.04  ? 199 THR B CA  1 
ATOM   3889  C  C   . THR B 1 199 ? -17.807 -6.849  -18.508 1.00 27.02  ? 199 THR B C   1 
ATOM   3890  O  O   . THR B 1 199 ? -17.190 -7.905  -18.711 1.00 26.53  ? 199 THR B O   1 
ATOM   3891  C  CB  . THR B 1 199 ? -18.663 -6.787  -16.139 1.00 26.58  ? 199 THR B CB  1 
ATOM   3892  O  OG1 . THR B 1 199 ? -19.853 -6.678  -15.366 1.00 29.77  ? 199 THR B OG1 1 
ATOM   3893  C  CG2 . THR B 1 199 ? -17.788 -5.598  -15.811 1.00 25.33  ? 199 THR B CG2 1 
ATOM   3894  N  N   . ILE B 1 200 ? -17.506 -5.705  -19.124 1.00 26.70  ? 200 ILE B N   1 
ATOM   3895  C  CA  . ILE B 1 200 ? -16.333 -5.581  -20.033 1.00 23.05  ? 200 ILE B CA  1 
ATOM   3896  C  C   . ILE B 1 200 ? -15.074 -5.540  -19.165 1.00 26.36  ? 200 ILE B C   1 
ATOM   3897  O  O   . ILE B 1 200 ? -14.691 -4.452  -18.732 1.00 23.19  ? 200 ILE B O   1 
ATOM   3898  C  CB  . ILE B 1 200 ? -16.528 -4.368  -20.961 1.00 18.04  ? 200 ILE B CB  1 
ATOM   3899  C  CG1 . ILE B 1 200 ? -17.986 -4.267  -21.421 1.00 24.12  ? 200 ILE B CG1 1 
ATOM   3900  C  CG2 . ILE B 1 200 ? -15.557 -4.402  -22.129 1.00 17.33  ? 200 ILE B CG2 1 
ATOM   3901  C  CD1 . ILE B 1 200 ? -18.391 -2.913  -21.956 1.00 19.61  ? 200 ILE B CD1 1 
ATOM   3902  N  N   . THR B 1 201 ? -14.454 -6.698  -18.962 1.00 23.10  ? 201 THR B N   1 
ATOM   3903  C  CA  . THR B 1 201 ? -13.320 -6.821  -18.045 1.00 17.71  ? 201 THR B CA  1 
ATOM   3904  C  C   . THR B 1 201 ? -12.154 -5.941  -18.469 1.00 19.83  ? 201 THR B C   1 
ATOM   3905  O  O   . THR B 1 201 ? -11.499 -5.306  -17.628 1.00 18.71  ? 201 THR B O   1 
ATOM   3906  C  CB  . THR B 1 201 ? -12.855 -8.269  -17.970 1.00 21.65  ? 201 THR B CB  1 
ATOM   3907  O  OG1 . THR B 1 201 ? -13.991 -9.143  -17.921 1.00 22.10  ? 201 THR B OG1 1 
ATOM   3908  C  CG2 . THR B 1 201 ? -12.019 -8.456  -16.725 1.00 18.24  ? 201 THR B CG2 1 
ATOM   3909  N  N   . VAL B 1 202 ? -11.837 -5.926  -19.764 1.00 18.63  ? 202 VAL B N   1 
ATOM   3910  C  CA  . VAL B 1 202 ? -10.709 -5.106  -20.196 1.00 20.68  ? 202 VAL B CA  1 
ATOM   3911  C  C   . VAL B 1 202 ? -10.943 -3.626  -19.858 1.00 17.61  ? 202 VAL B C   1 
ATOM   3912  O  O   . VAL B 1 202 ? -10.007 -2.922  -19.469 1.00 20.13  ? 202 VAL B O   1 
ATOM   3913  C  CB  . VAL B 1 202 ? -10.429 -5.347  -21.692 1.00 20.60  ? 202 VAL B CB  1 
ATOM   3914  C  CG1 . VAL B 1 202 ? -11.633 -4.959  -22.536 1.00 21.90  ? 202 VAL B CG1 1 
ATOM   3915  C  CG2 . VAL B 1 202 ? -9.176  -4.542  -22.123 1.00 18.66  ? 202 VAL B CG2 1 
ATOM   3916  N  N   . ASN B 1 203 ? -12.193 -3.153  -19.898 1.00 18.90  ? 203 ASN B N   1 
ATOM   3917  C  CA  . ASN B 1 203 ? -12.441 -1.760  -19.520 1.00 19.28  ? 203 ASN B CA  1 
ATOM   3918  C  C   . ASN B 1 203 ? -12.321 -1.551  -18.006 1.00 19.76  ? 203 ASN B C   1 
ATOM   3919  O  O   . ASN B 1 203 ? -11.790 -0.527  -17.558 1.00 21.16  ? 203 ASN B O   1 
ATOM   3920  C  CB  . ASN B 1 203 ? -13.817 -1.313  -20.005 1.00 17.77  ? 203 ASN B CB  1 
ATOM   3921  C  CG  . ASN B 1 203 ? -13.893 -1.155  -21.514 1.00 20.02  ? 203 ASN B CG  1 
ATOM   3922  O  OD1 . ASN B 1 203 ? -12.917 -1.335  -22.221 1.00 21.60  ? 203 ASN B OD1 1 
ATOM   3923  N  ND2 . ASN B 1 203 ? -15.068 -0.816  -22.008 1.00 22.65  ? 203 ASN B ND2 1 
ATOM   3924  N  N   . VAL B 1 204 ? -12.784 -2.509  -17.197 1.00 19.15  ? 204 VAL B N   1 
ATOM   3925  C  CA  . VAL B 1 204 ? -12.630 -2.376  -15.750 1.00 20.14  ? 204 VAL B CA  1 
ATOM   3926  C  C   . VAL B 1 204 ? -11.155 -2.252  -15.393 1.00 19.15  ? 204 VAL B C   1 
ATOM   3927  O  O   . VAL B 1 204 ? -10.759 -1.397  -14.589 1.00 17.05  ? 204 VAL B O   1 
ATOM   3928  C  CB  . VAL B 1 204 ? -13.264 -3.575  -15.019 1.00 22.31  ? 204 VAL B CB  1 
ATOM   3929  C  CG1 . VAL B 1 204 ? -12.973 -3.479  -13.519 1.00 16.27  ? 204 VAL B CG1 1 
ATOM   3930  C  CG2 . VAL B 1 204 ? -14.769 -3.661  -15.295 1.00 21.55  ? 204 VAL B CG2 1 
ATOM   3931  N  N   . LEU B 1 205 ? -10.324 -3.114  -15.993 1.00 16.25  ? 205 LEU B N   1 
ATOM   3932  C  CA  . LEU B 1 205 ? -8.893  -3.067  -15.759 1.00 17.48  ? 205 LEU B CA  1 
ATOM   3933  C  C   . LEU B 1 205 ? -8.303  -1.720  -16.167 1.00 16.29  ? 205 LEU B C   1 
ATOM   3934  O  O   . LEU B 1 205 ? -7.489  -1.147  -15.435 1.00 15.14  ? 205 LEU B O   1 
ATOM   3935  C  CB  . LEU B 1 205 ? -8.214  -4.217  -16.506 1.00 15.70  ? 205 LEU B CB  1 
ATOM   3936  C  CG  . LEU B 1 205 ? -8.524  -5.592  -15.855 1.00 22.16  ? 205 LEU B CG  1 
ATOM   3937  C  CD1 . LEU B 1 205 ? -8.194  -6.756  -16.781 1.00 14.63  ? 205 LEU B CD1 1 
ATOM   3938  C  CD2 . LEU B 1 205 ? -7.820  -5.747  -14.495 1.00 13.88  ? 205 LEU B CD2 1 
ATOM   3939  N  N   . ALA B 1 206 ? -8.697  -1.203  -17.335 1.00 16.83  ? 206 ALA B N   1 
ATOM   3940  C  CA  . ALA B 1 206 ? -8.238  0.115   -17.766 1.00 16.11  ? 206 ALA B CA  1 
ATOM   3941  C  C   . ALA B 1 206 ? -8.588  1.176   -16.736 1.00 20.75  ? 206 ALA B C   1 
ATOM   3942  O  O   . ALA B 1 206 ? -7.784  2.084   -16.453 1.00 16.29  ? 206 ALA B O   1 
ATOM   3943  C  CB  . ALA B 1 206 ? -8.866  0.473   -19.114 1.00 17.64  ? 206 ALA B CB  1 
ATOM   3944  N  N   . TRP B 1 207 ? -9.783  1.073   -16.157 1.00 17.15  ? 207 TRP B N   1 
ATOM   3945  C  CA  . TRP B 1 207 ? -10.243 2.116   -15.250 1.00 18.10  ? 207 TRP B CA  1 
ATOM   3946  C  C   . TRP B 1 207 ? -9.504  2.048   -13.923 1.00 22.89  ? 207 TRP B C   1 
ATOM   3947  O  O   . TRP B 1 207 ? -9.165  3.094   -13.342 1.00 21.96  ? 207 TRP B O   1 
ATOM   3948  C  CB  . TRP B 1 207 ? -11.755 1.994   -15.091 1.00 20.28  ? 207 TRP B CB  1 
ATOM   3949  C  CG  . TRP B 1 207 ? -12.380 2.789   -13.998 1.00 25.44  ? 207 TRP B CG  1 
ATOM   3950  C  CD1 . TRP B 1 207 ? -12.711 4.117   -14.020 1.00 23.46  ? 207 TRP B CD1 1 
ATOM   3951  C  CD2 . TRP B 1 207 ? -12.804 2.292   -12.731 1.00 24.38  ? 207 TRP B CD2 1 
ATOM   3952  N  NE1 . TRP B 1 207 ? -13.313 4.474   -12.832 1.00 24.51  ? 207 TRP B NE1 1 
ATOM   3953  C  CE2 . TRP B 1 207 ? -13.376 3.371   -12.025 1.00 25.55  ? 207 TRP B CE2 1 
ATOM   3954  C  CE3 . TRP B 1 207 ? -12.751 1.036   -12.118 1.00 24.82  ? 207 TRP B CE3 1 
ATOM   3955  C  CZ2 . TRP B 1 207 ? -13.878 3.234   -10.744 1.00 24.14  ? 207 TRP B CZ2 1 
ATOM   3956  C  CZ3 . TRP B 1 207 ? -13.261 0.903   -10.856 1.00 21.96  ? 207 TRP B CZ3 1 
ATOM   3957  C  CH2 . TRP B 1 207 ? -13.809 2.001   -10.175 1.00 23.06  ? 207 TRP B CH2 1 
ATOM   3958  N  N   . LEU B 1 208 ? -9.180  0.829   -13.461 1.00 19.76  ? 208 LEU B N   1 
ATOM   3959  C  CA  . LEU B 1 208 ? -8.305  0.692   -12.298 1.00 18.17  ? 208 LEU B CA  1 
ATOM   3960  C  C   . LEU B 1 208 ? -6.938  1.337   -12.556 1.00 19.11  ? 208 LEU B C   1 
ATOM   3961  O  O   . LEU B 1 208 ? -6.365  1.989   -11.666 1.00 17.32  ? 208 LEU B O   1 
ATOM   3962  C  CB  . LEU B 1 208 ? -8.162  -0.795  -11.929 1.00 16.33  ? 208 LEU B CB  1 
ATOM   3963  C  CG  . LEU B 1 208 ? -9.456  -1.404  -11.367 1.00 16.77  ? 208 LEU B CG  1 
ATOM   3964  C  CD1 . LEU B 1 208 ? -9.406  -2.925  -11.250 1.00 14.96  ? 208 LEU B CD1 1 
ATOM   3965  C  CD2 . LEU B 1 208 ? -9.777  -0.784  -10.008 1.00 12.92  ? 208 LEU B CD2 1 
ATOM   3966  N  N   . TYR B 1 209 ? -6.409  1.184   -13.772 1.00 15.76  ? 209 TYR B N   1 
ATOM   3967  C  CA  . TYR B 1 209 ? -5.151  1.842   -14.097 1.00 18.37  ? 209 TYR B CA  1 
ATOM   3968  C  C   . TYR B 1 209 ? -5.318  3.357   -14.044 1.00 19.57  ? 209 TYR B C   1 
ATOM   3969  O  O   . TYR B 1 209 ? -4.478  4.058   -13.468 1.00 19.53  ? 209 TYR B O   1 
ATOM   3970  C  CB  . TYR B 1 209 ? -4.653  1.400   -15.476 1.00 17.83  ? 209 TYR B CB  1 
ATOM   3971  C  CG  . TYR B 1 209 ? -3.939  0.074   -15.488 1.00 22.82  ? 209 TYR B CG  1 
ATOM   3972  C  CD1 . TYR B 1 209 ? -2.712  -0.077  -14.852 1.00 25.58  ? 209 TYR B CD1 1 
ATOM   3973  C  CD2 . TYR B 1 209 ? -4.479  -1.043  -16.145 1.00 23.67  ? 209 TYR B CD2 1 
ATOM   3974  C  CE1 . TYR B 1 209 ? -2.057  -1.287  -14.847 1.00 22.37  ? 209 TYR B CE1 1 
ATOM   3975  C  CE2 . TYR B 1 209 ? -3.818  -2.265  -16.149 1.00 18.44  ? 209 TYR B CE2 1 
ATOM   3976  C  CZ  . TYR B 1 209 ? -2.610  -2.371  -15.504 1.00 23.50  ? 209 TYR B CZ  1 
ATOM   3977  O  OH  . TYR B 1 209 ? -1.911  -3.558  -15.477 1.00 25.84  ? 209 TYR B OH  1 
ATOM   3978  N  N   . ALA B 1 210 ? -6.412  3.878   -14.619 1.00 15.96  ? 210 ALA B N   1 
ATOM   3979  C  CA  . ALA B 1 210 ? -6.705  5.301   -14.478 1.00 18.32  ? 210 ALA B CA  1 
ATOM   3980  C  C   . ALA B 1 210 ? -6.717  5.708   -13.009 1.00 20.61  ? 210 ALA B C   1 
ATOM   3981  O  O   . ALA B 1 210 ? -6.201  6.767   -12.650 1.00 22.50  ? 210 ALA B O   1 
ATOM   3982  C  CB  . ALA B 1 210 ? -8.048  5.646   -15.138 1.00 16.22  ? 210 ALA B CB  1 
ATOM   3983  N  N   . ALA B 1 211 ? -7.281  4.864   -12.141 1.00 18.91  ? 211 ALA B N   1 
ATOM   3984  C  CA  . ALA B 1 211 ? -7.320  5.176   -10.719 1.00 16.78  ? 211 ALA B CA  1 
ATOM   3985  C  C   . ALA B 1 211 ? -5.922  5.283   -10.150 1.00 20.93  ? 211 ALA B C   1 
ATOM   3986  O  O   . ALA B 1 211 ? -5.648  6.153   -9.314  1.00 19.72  ? 211 ALA B O   1 
ATOM   3987  C  CB  . ALA B 1 211 ? -8.122  4.118   -9.960  1.00 18.29  ? 211 ALA B CB  1 
ATOM   3988  N  N   . VAL B 1 212 ? -5.049  4.347   -10.522 1.00 20.96  ? 212 VAL B N   1 
ATOM   3989  C  CA  . VAL B 1 212 ? -3.662  4.400   -10.066 1.00 22.28  ? 212 VAL B CA  1 
ATOM   3990  C  C   . VAL B 1 212 ? -2.990  5.675   -10.567 1.00 20.90  ? 212 VAL B C   1 
ATOM   3991  O  O   . VAL B 1 212 ? -2.302  6.376   -9.814  1.00 21.82  ? 212 VAL B O   1 
ATOM   3992  C  CB  . VAL B 1 212 ? -2.896  3.146   -10.531 1.00 18.78  ? 212 VAL B CB  1 
ATOM   3993  C  CG1 . VAL B 1 212 ? -1.438  3.280   -10.206 1.00 16.56  ? 212 VAL B CG1 1 
ATOM   3994  C  CG2 . VAL B 1 212 ? -3.487  1.887   -9.901  1.00 21.77  ? 212 VAL B CG2 1 
ATOM   3995  N  N   . ILE B 1 213 ? -3.178  5.989   -11.852 1.00 18.99  ? 213 ILE B N   1 
ATOM   3996  C  CA  . ILE B 1 213 ? -2.609  7.205   -12.421 1.00 18.64  ? 213 ILE B CA  1 
ATOM   3997  C  C   . ILE B 1 213 ? -3.015  8.414   -11.596 1.00 25.28  ? 213 ILE B C   1 
ATOM   3998  O  O   . ILE B 1 213 ? -2.215  9.336   -11.414 1.00 26.85  ? 213 ILE B O   1 
ATOM   3999  C  CB  . ILE B 1 213 ? -3.016  7.362   -13.902 1.00 26.15  ? 213 ILE B CB  1 
ATOM   4000  C  CG1 . ILE B 1 213 ? -2.327  6.320   -14.783 1.00 23.97  ? 213 ILE B CG1 1 
ATOM   4001  C  CG2 . ILE B 1 213 ? -2.698  8.773   -14.443 1.00 25.06  ? 213 ILE B CG2 1 
ATOM   4002  C  CD1 . ILE B 1 213 ? -2.931  6.241   -16.198 1.00 21.79  ? 213 ILE B CD1 1 
ATOM   4003  N  N   . ASN B 1 214 ? -4.220  8.404   -11.016 1.00 25.22  ? 214 ASN B N   1 
ATOM   4004  C  CA  . ASN B 1 214 ? -4.713  9.539   -10.251 1.00 22.98  ? 214 ASN B CA  1 
ATOM   4005  C  C   . ASN B 1 214 ? -4.471  9.427   -8.753  1.00 26.97  ? 214 ASN B C   1 
ATOM   4006  O  O   . ASN B 1 214 ? -4.956  10.282  -8.000  1.00 29.77  ? 214 ASN B O   1 
ATOM   4007  C  CB  . ASN B 1 214 ? -6.212  9.728   -10.493 1.00 24.99  ? 214 ASN B CB  1 
ATOM   4008  C  CG  . ASN B 1 214 ? -6.506  10.457  -11.774 1.00 29.06  ? 214 ASN B CG  1 
ATOM   4009  O  OD1 . ASN B 1 214 ? -6.539  11.691  -11.780 1.00 34.44  ? 214 ASN B OD1 1 
ATOM   4010  N  ND2 . ASN B 1 214 ? -6.715  9.719   -12.869 1.00 21.46  ? 214 ASN B ND2 1 
ATOM   4011  N  N   . GLY B 1 215 ? -3.682  8.454   -8.300  1.00 25.25  ? 215 GLY B N   1 
ATOM   4012  C  CA  . GLY B 1 215 ? -3.371  8.375   -6.892  1.00 20.45  ? 215 GLY B CA  1 
ATOM   4013  C  C   . GLY B 1 215 ? -4.342  7.548   -6.064  1.00 29.24  ? 215 GLY B C   1 
ATOM   4014  O  O   . GLY B 1 215 ? -4.115  7.388   -4.859  1.00 28.90  ? 215 GLY B O   1 
ATOM   4015  N  N   . ASP B 1 216 ? -5.434  7.054   -6.631  1.00 21.06  ? 216 ASP B N   1 
ATOM   4016  C  CA  . ASP B 1 216 ? -6.341  6.138   -5.891  1.00 30.74  ? 216 ASP B CA  1 
ATOM   4017  C  C   . ASP B 1 216 ? -5.716  4.734   -5.955  1.00 29.09  ? 216 ASP B C   1 
ATOM   4018  O  O   . ASP B 1 216 ? -5.873  4.097   -6.992  1.00 28.61  ? 216 ASP B O   1 
ATOM   4019  C  CB  . ASP B 1 216 ? -7.762  6.236   -6.458  1.00 28.60  ? 216 ASP B CB  1 
ATOM   4020  C  CG  . ASP B 1 216 ? -8.880  6.434   -5.454  1.00 33.20  ? 216 ASP B CG  1 
ATOM   4021  O  OD1 . ASP B 1 216 ? -8.770  5.917   -4.335  1.00 36.28  ? 216 ASP B OD1 1 
ATOM   4022  O  OD2 . ASP B 1 216 ? -9.869  7.083   -5.823  1.00 33.85  ? 216 ASP B OD2 1 
ATOM   4023  N  N   . ARG B 1 217 ? -5.046  4.270   -4.890  1.00 26.75  ? 217 ARG B N   1 
ATOM   4024  C  CA  . ARG B 1 217 ? -4.289  2.988   -4.945  1.00 29.31  ? 217 ARG B CA  1 
ATOM   4025  C  C   . ARG B 1 217 ? -4.533  2.037   -3.756  1.00 31.30  ? 217 ARG B C   1 
ATOM   4026  O  O   . ARG B 1 217 ? -3.749  1.092   -3.618  1.00 32.05  ? 217 ARG B O   1 
ATOM   4027  C  CB  . ARG B 1 217 ? -2.801  3.314   -5.060  1.00 30.21  ? 217 ARG B CB  1 
ATOM   4028  C  CG  . ARG B 1 217 ? -2.330  4.469   -4.191  1.00 45.38  ? 217 ARG B CG  1 
ATOM   4029  C  CD  . ARG B 1 217 ? -0.839  4.712   -4.321  1.00 46.82  ? 217 ARG B CD  1 
ATOM   4030  N  NE  . ARG B 1 217 ? -0.181  4.735   -3.021  1.00 47.78  ? 217 ARG B NE  1 
ATOM   4031  C  CZ  . ARG B 1 217 ? 0.299   3.669   -2.388  1.00 44.40  ? 217 ARG B CZ  1 
ATOM   4032  N  NH1 . ARG B 1 217 ? 0.210   2.468   -2.934  1.00 49.21  ? 217 ARG B NH1 1 
ATOM   4033  N  NH2 . ARG B 1 217 ? 0.867   3.807   -1.206  1.00 36.92  ? 217 ARG B NH2 1 
ATOM   4034  N  N   . TRP B 1 218 ? -5.589  2.240   -2.970  1.00 30.92  ? 218 TRP B N   1 
ATOM   4035  C  CA  . TRP B 1 218 ? -5.897  1.382   -1.789  1.00 32.65  ? 218 TRP B CA  1 
ATOM   4036  C  C   . TRP B 1 218 ? -6.165  -0.076  -2.193  1.00 26.95  ? 218 TRP B C   1 
ATOM   4037  O  O   . TRP B 1 218 ? -5.923  -0.947  -1.369  1.00 25.52  ? 218 TRP B O   1 
ATOM   4038  C  CB  . TRP B 1 218 ? -7.079  1.958   -0.997  1.00 26.21  ? 218 TRP B CB  1 
ATOM   4039  C  CG  . TRP B 1 218 ? -8.383  2.040   -1.727  1.00 28.35  ? 218 TRP B CG  1 
ATOM   4040  C  CD1 . TRP B 1 218 ? -8.878  3.126   -2.383  1.00 25.23  ? 218 TRP B CD1 1 
ATOM   4041  C  CD2 . TRP B 1 218 ? -9.380  1.011   -1.852  1.00 27.82  ? 218 TRP B CD2 1 
ATOM   4042  N  NE1 . TRP B 1 218 ? -10.102 2.841   -2.913  1.00 22.57  ? 218 TRP B NE1 1 
ATOM   4043  C  CE2 . TRP B 1 218 ? -10.436 1.552   -2.608  1.00 25.79  ? 218 TRP B CE2 1 
ATOM   4044  C  CE3 . TRP B 1 218 ? -9.479  -0.317  -1.425  1.00 33.84  ? 218 TRP B CE3 1 
ATOM   4045  C  CZ2 . TRP B 1 218 ? -11.575 0.816   -2.926  1.00 27.58  ? 218 TRP B CZ2 1 
ATOM   4046  C  CZ3 . TRP B 1 218 ? -10.599 -1.046  -1.748  1.00 25.05  ? 218 TRP B CZ3 1 
ATOM   4047  C  CH2 . TRP B 1 218 ? -11.636 -0.484  -2.488  1.00 25.59  ? 218 TRP B CH2 1 
ATOM   4048  N  N   . PHE B 1 219 ? -6.625  -0.312  -3.414  1.00 24.34  ? 219 PHE B N   1 
ATOM   4049  C  CA  . PHE B 1 219 ? -7.037  -1.629  -3.879  1.00 28.56  ? 219 PHE B CA  1 
ATOM   4050  C  C   . PHE B 1 219 ? -5.887  -2.488  -4.398  1.00 30.14  ? 219 PHE B C   1 
ATOM   4051  O  O   . PHE B 1 219 ? -6.118  -3.654  -4.735  1.00 28.95  ? 219 PHE B O   1 
ATOM   4052  C  CB  . PHE B 1 219 ? -8.090  -1.479  -4.978  1.00 21.99  ? 219 PHE B CB  1 
ATOM   4053  C  CG  . PHE B 1 219 ? -7.664  -0.570  -6.094  1.00 22.79  ? 219 PHE B CG  1 
ATOM   4054  C  CD1 . PHE B 1 219 ? -6.910  -1.055  -7.155  1.00 21.17  ? 219 PHE B CD1 1 
ATOM   4055  C  CD2 . PHE B 1 219 ? -8.027  0.779   -6.088  1.00 23.53  ? 219 PHE B CD2 1 
ATOM   4056  C  CE1 . PHE B 1 219 ? -6.513  -0.211  -8.197  1.00 22.94  ? 219 PHE B CE1 1 
ATOM   4057  C  CE2 . PHE B 1 219 ? -7.643  1.619   -7.119  1.00 21.30  ? 219 PHE B CE2 1 
ATOM   4058  C  CZ  . PHE B 1 219 ? -6.872  1.123   -8.171  1.00 22.26  ? 219 PHE B CZ  1 
ATOM   4059  N  N   . LEU B 1 220 ? -4.682  -1.942  -4.509  1.00 29.02  ? 220 LEU B N   1 
ATOM   4060  C  CA  . LEU B 1 220 ? -3.528  -2.722  -4.941  1.00 29.26  ? 220 LEU B CA  1 
ATOM   4061  C  C   . LEU B 1 220 ? -3.048  -3.625  -3.809  1.00 25.79  ? 220 LEU B C   1 
ATOM   4062  O  O   . LEU B 1 220 ? -3.143  -3.265  -2.629  1.00 22.70  ? 220 LEU B O   1 
ATOM   4063  C  CB  . LEU B 1 220 ? -2.387  -1.799  -5.403  1.00 22.53  ? 220 LEU B CB  1 
ATOM   4064  C  CG  . LEU B 1 220 ? -2.691  -0.862  -6.588  1.00 27.94  ? 220 LEU B CG  1 
ATOM   4065  C  CD1 . LEU B 1 220 ? -1.569  0.163   -6.838  1.00 22.94  ? 220 LEU B CD1 1 
ATOM   4066  C  CD2 . LEU B 1 220 ? -3.002  -1.634  -7.873  1.00 22.30  ? 220 LEU B CD2 1 
ATOM   4067  N  N   . ASN B 1 221 ? -2.607  -4.834  -4.168  1.00 25.95  ? 221 ASN B N   1 
ATOM   4068  C  CA  . ASN B 1 221 ? -2.044  -5.767  -3.193  1.00 28.86  ? 221 ASN B CA  1 
ATOM   4069  C  C   . ASN B 1 221 ? -0.688  -6.277  -3.700  1.00 25.97  ? 221 ASN B C   1 
ATOM   4070  O  O   . ASN B 1 221 ? -0.203  -5.878  -4.759  1.00 29.45  ? 221 ASN B O   1 
ATOM   4071  C  CB  . ASN B 1 221 ? -3.035  -6.903  -2.875  1.00 25.74  ? 221 ASN B CB  1 
ATOM   4072  C  CG  . ASN B 1 221 ? -3.409  -7.749  -4.096  1.00 30.42  ? 221 ASN B CG  1 
ATOM   4073  O  OD1 . ASN B 1 221 ? -2.608  -7.943  -5.006  1.00 28.81  ? 221 ASN B OD1 1 
ATOM   4074  N  ND2 . ASN B 1 221 ? -4.647  -8.249  -4.116  1.00 28.37  ? 221 ASN B ND2 1 
ATOM   4075  N  N   . ARG B 1 222 ? -0.062  -7.167  -2.942  1.00 28.86  ? 222 ARG B N   1 
ATOM   4076  C  CA  . ARG B 1 222 ? 1.237   -7.698  -3.334  1.00 36.41  ? 222 ARG B CA  1 
ATOM   4077  C  C   . ARG B 1 222 ? 1.158   -9.015  -4.102  1.00 35.60  ? 222 ARG B C   1 
ATOM   4078  O  O   . ARG B 1 222 ? 2.180   -9.688  -4.255  1.00 39.78  ? 222 ARG B O   1 
ATOM   4079  C  CB  . ARG B 1 222 ? 2.155   -7.869  -2.118  1.00 40.36  ? 222 ARG B CB  1 
ATOM   4080  C  CG  . ARG B 1 222 ? 2.705   -6.555  -1.611  1.00 53.12  ? 222 ARG B CG  1 
ATOM   4081  C  CD  . ARG B 1 222 ? 3.771   -6.743  -0.518  1.00 60.35  ? 222 ARG B CD  1 
ATOM   4082  N  NE  . ARG B 1 222 ? 4.412   -5.460  -0.232  1.00 64.03  ? 222 ARG B NE  1 
ATOM   4083  C  CZ  . ARG B 1 222 ? 5.476   -4.989  -0.872  1.00 60.30  ? 222 ARG B CZ  1 
ATOM   4084  N  NH1 . ARG B 1 222 ? 6.051   -5.668  -1.854  1.00 49.86  ? 222 ARG B NH1 1 
ATOM   4085  N  NH2 . ARG B 1 222 ? 5.955   -3.789  -0.541  1.00 64.56  ? 222 ARG B NH2 1 
ATOM   4086  N  N   . PHE B 1 223 ? -0.016  -9.396  -4.587  1.00 35.28  ? 223 PHE B N   1 
ATOM   4087  C  CA  . PHE B 1 223 ? -0.220  -10.704 -5.188  1.00 32.39  ? 223 PHE B CA  1 
ATOM   4088  C  C   . PHE B 1 223 ? -0.201  -10.598 -6.697  1.00 27.48  ? 223 PHE B C   1 
ATOM   4089  O  O   . PHE B 1 223 ? -0.351  -9.519  -7.276  1.00 35.27  ? 223 PHE B O   1 
ATOM   4090  C  CB  . PHE B 1 223 ? -1.553  -11.308 -4.752  1.00 27.42  ? 223 PHE B CB  1 
ATOM   4091  C  CG  . PHE B 1 223 ? -1.721  -11.391 -3.277  1.00 35.17  ? 223 PHE B CG  1 
ATOM   4092  C  CD1 . PHE B 1 223 ? -0.616  -11.469 -2.438  1.00 41.06  ? 223 PHE B CD1 1 
ATOM   4093  C  CD2 . PHE B 1 223 ? -2.989  -11.386 -2.720  1.00 43.99  ? 223 PHE B CD2 1 
ATOM   4094  C  CE1 . PHE B 1 223 ? -0.773  -11.549 -1.061  1.00 47.69  ? 223 PHE B CE1 1 
ATOM   4095  C  CE2 . PHE B 1 223 ? -3.161  -11.471 -1.345  1.00 49.55  ? 223 PHE B CE2 1 
ATOM   4096  C  CZ  . PHE B 1 223 ? -2.048  -11.553 -0.513  1.00 51.71  ? 223 PHE B CZ  1 
ATOM   4097  N  N   . THR B 1 224 ? -0.059  -11.742 -7.330  1.00 21.30  ? 224 THR B N   1 
ATOM   4098  C  CA  . THR B 1 224 ? -0.282  -11.857 -8.752  1.00 19.97  ? 224 THR B CA  1 
ATOM   4099  C  C   . THR B 1 224 ? -1.232  -13.020 -8.983  1.00 24.55  ? 224 THR B C   1 
ATOM   4100  O  O   . THR B 1 224 ? -1.684  -13.671 -8.039  1.00 21.42  ? 224 THR B O   1 
ATOM   4101  C  CB  . THR B 1 224 ? 1.037   -12.033 -9.506  1.00 25.53  ? 224 THR B CB  1 
ATOM   4102  O  OG1 . THR B 1 224 ? 0.833   -11.741 -10.899 1.00 28.54  ? 224 THR B OG1 1 
ATOM   4103  C  CG2 . THR B 1 224 ? 1.586   -13.440 -9.322  1.00 22.09  ? 224 THR B CG2 1 
ATOM   4104  N  N   . THR B 1 225 ? -1.621  -13.218 -10.235 1.00 24.24  ? 225 THR B N   1 
ATOM   4105  C  CA  . THR B 1 225 ? -2.520  -14.306 -10.582 1.00 22.51  ? 225 THR B CA  1 
ATOM   4106  C  C   . THR B 1 225 ? -2.176  -14.751 -12.001 1.00 24.19  ? 225 THR B C   1 
ATOM   4107  O  O   . THR B 1 225 ? -1.236  -14.238 -12.623 1.00 20.07  ? 225 THR B O   1 
ATOM   4108  C  CB  . THR B 1 225 ? -3.992  -13.883 -10.404 1.00 25.70  ? 225 THR B CB  1 
ATOM   4109  O  OG1 . THR B 1 225 ? -4.840  -15.038 -10.438 1.00 25.07  ? 225 THR B OG1 1 
ATOM   4110  C  CG2 . THR B 1 225 ? -4.448  -12.883 -11.502 1.00 19.99  ? 225 THR B CG2 1 
ATOM   4111  N  N   . THR B 1 226 ? -2.915  -15.743 -12.496 1.00 21.03  ? 226 THR B N   1 
ATOM   4112  C  CA  . THR B 1 226 ? -2.841  -16.152 -13.893 1.00 20.55  ? 226 THR B CA  1 
ATOM   4113  C  C   . THR B 1 226 ? -4.148  -15.812 -14.595 1.00 20.10  ? 226 THR B C   1 
ATOM   4114  O  O   . THR B 1 226 ? -5.160  -15.527 -13.959 1.00 21.53  ? 226 THR B O   1 
ATOM   4115  C  CB  . THR B 1 226 ? -2.563  -17.659 -14.023 1.00 25.89  ? 226 THR B CB  1 
ATOM   4116  O  OG1 . THR B 1 226 ? -3.711  -18.402 -13.565 1.00 25.32  ? 226 THR B OG1 1 
ATOM   4117  C  CG2 . THR B 1 226 ? -1.316  -18.065 -13.215 1.00 19.47  ? 226 THR B CG2 1 
ATOM   4118  N  N   . LEU B 1 227 ? -4.108  -15.827 -15.924 1.00 21.64  ? 227 LEU B N   1 
ATOM   4119  C  CA  . LEU B 1 227 ? -5.324  -15.658 -16.713 1.00 23.22  ? 227 LEU B CA  1 
ATOM   4120  C  C   . LEU B 1 227 ? -6.372  -16.713 -16.348 1.00 28.27  ? 227 LEU B C   1 
ATOM   4121  O  O   . LEU B 1 227 ? -7.573  -16.411 -16.255 1.00 28.46  ? 227 LEU B O   1 
ATOM   4122  C  CB  . LEU B 1 227 ? -4.963  -15.714 -18.199 1.00 25.92  ? 227 LEU B CB  1 
ATOM   4123  C  CG  . LEU B 1 227 ? -5.518  -14.657 -19.151 1.00 31.34  ? 227 LEU B CG  1 
ATOM   4124  C  CD1 . LEU B 1 227 ? -5.433  -13.282 -18.530 1.00 26.23  ? 227 LEU B CD1 1 
ATOM   4125  C  CD2 . LEU B 1 227 ? -4.713  -14.678 -20.428 1.00 28.85  ? 227 LEU B CD2 1 
ATOM   4126  N  N   . ASN B 1 228 ? -5.933  -17.956 -16.109 1.00 24.59  ? 228 ASN B N   1 
ATOM   4127  C  CA  . ASN B 1 228 ? -6.860  -19.024 -15.739 1.00 25.04  ? 228 ASN B CA  1 
ATOM   4128  C  C   . ASN B 1 228 ? -7.490  -18.795 -14.369 1.00 23.49  ? 228 ASN B C   1 
ATOM   4129  O  O   . ASN B 1 228 ? -8.711  -18.901 -14.211 1.00 27.33  ? 228 ASN B O   1 
ATOM   4130  C  CB  . ASN B 1 228 ? -6.142  -20.370 -15.774 1.00 26.70  ? 228 ASN B CB  1 
ATOM   4131  C  CG  . ASN B 1 228 ? -6.000  -20.916 -17.183 1.00 29.95  ? 228 ASN B CG  1 
ATOM   4132  O  OD1 . ASN B 1 228 ? -6.458  -20.302 -18.152 1.00 30.29  ? 228 ASN B OD1 1 
ATOM   4133  N  ND2 . ASN B 1 228 ? -5.306  -22.043 -17.310 1.00 29.58  ? 228 ASN B ND2 1 
ATOM   4134  N  N   . ASP B 1 229 ? -6.679  -18.516 -13.354 1.00 25.31  ? 229 ASP B N   1 
ATOM   4135  C  CA  . ASP B 1 229 ? -7.248  -18.356 -12.020 1.00 24.42  ? 229 ASP B CA  1 
ATOM   4136  C  C   . ASP B 1 229 ? -8.145  -17.131 -11.953 1.00 25.55  ? 229 ASP B C   1 
ATOM   4137  O  O   . ASP B 1 229 ? -9.203  -17.168 -11.314 1.00 27.66  ? 229 ASP B O   1 
ATOM   4138  C  CB  . ASP B 1 229 ? -6.127  -18.301 -10.980 1.00 27.72  ? 229 ASP B CB  1 
ATOM   4139  C  CG  . ASP B 1 229 ? -5.751  -19.702 -10.466 1.00 33.62  ? 229 ASP B CG  1 
ATOM   4140  O  OD1 . ASP B 1 229 ? -6.148  -20.692 -11.133 1.00 41.95  ? 229 ASP B OD1 1 
ATOM   4141  O  OD2 . ASP B 1 229 ? -5.026  -19.828 -9.449  1.00 35.59  ? 229 ASP B OD2 1 
ATOM   4142  N  N   . PHE B 1 230 ? -7.772  -16.060 -12.664 1.00 25.59  ? 230 PHE B N   1 
ATOM   4143  C  CA  . PHE B 1 230 ? -8.633  -14.883 -12.759 1.00 25.73  ? 230 PHE B CA  1 
ATOM   4144  C  C   . PHE B 1 230 ? -9.942  -15.179 -13.474 1.00 22.89  ? 230 PHE B C   1 
ATOM   4145  O  O   . PHE B 1 230 ? -11.013 -14.738 -13.041 1.00 20.17  ? 230 PHE B O   1 
ATOM   4146  C  CB  . PHE B 1 230 ? -7.936  -13.744 -13.497 1.00 18.33  ? 230 PHE B CB  1 
ATOM   4147  C  CG  . PHE B 1 230 ? -8.855  -12.606 -13.758 1.00 21.75  ? 230 PHE B CG  1 
ATOM   4148  C  CD1 . PHE B 1 230 ? -9.137  -11.684 -12.754 1.00 23.20  ? 230 PHE B CD1 1 
ATOM   4149  C  CD2 . PHE B 1 230 ? -9.499  -12.484 -14.979 1.00 20.87  ? 230 PHE B CD2 1 
ATOM   4150  C  CE1 . PHE B 1 230 ? -10.035 -10.648 -12.975 1.00 22.47  ? 230 PHE B CE1 1 
ATOM   4151  C  CE2 . PHE B 1 230 ? -10.401 -11.455 -15.203 1.00 23.91  ? 230 PHE B CE2 1 
ATOM   4152  C  CZ  . PHE B 1 230 ? -10.664 -10.533 -14.196 1.00 23.45  ? 230 PHE B CZ  1 
ATOM   4153  N  N   . ASN B 1 231 ? -9.872  -15.860 -14.617 1.00 22.64  ? 231 ASN B N   1 
ATOM   4154  C  CA  . ASN B 1 231 ? -11.099 -16.087 -15.361 1.00 23.64  ? 231 ASN B CA  1 
ATOM   4155  C  C   . ASN B 1 231 ? -12.036 -17.010 -14.605 1.00 25.61  ? 231 ASN B C   1 
ATOM   4156  O  O   . ASN B 1 231 ? -13.254 -16.939 -14.801 1.00 26.28  ? 231 ASN B O   1 
ATOM   4157  C  CB  . ASN B 1 231 ? -10.798 -16.644 -16.752 1.00 23.33  ? 231 ASN B CB  1 
ATOM   4158  C  CG  . ASN B 1 231 ? -10.340 -15.564 -17.727 1.00 25.43  ? 231 ASN B CG  1 
ATOM   4159  O  OD1 . ASN B 1 231 ? -10.776 -14.409 -17.657 1.00 25.79  ? 231 ASN B OD1 1 
ATOM   4160  N  ND2 . ASN B 1 231 ? -9.494  -15.951 -18.672 1.00 22.29  ? 231 ASN B ND2 1 
ATOM   4161  N  N   . LEU B 1 232 ? -11.498 -17.883 -13.746 1.00 23.59  ? 232 LEU B N   1 
ATOM   4162  C  CA  . LEU B 1 232 ? -12.359 -18.671 -12.868 1.00 29.82  ? 232 LEU B CA  1 
ATOM   4163  C  C   . LEU B 1 232 ? -13.236 -17.767 -12.023 1.00 31.07  ? 232 LEU B C   1 
ATOM   4164  O  O   . LEU B 1 232 ? -14.453 -17.965 -11.944 1.00 30.82  ? 232 LEU B O   1 
ATOM   4165  C  CB  . LEU B 1 232 ? -11.520 -19.577 -11.969 1.00 34.01  ? 232 LEU B CB  1 
ATOM   4166  C  CG  . LEU B 1 232 ? -11.341 -20.998 -12.490 1.00 36.55  ? 232 LEU B CG  1 
ATOM   4167  C  CD1 . LEU B 1 232 ? -10.911 -21.923 -11.358 1.00 37.38  ? 232 LEU B CD1 1 
ATOM   4168  C  CD2 . LEU B 1 232 ? -12.623 -21.488 -13.172 1.00 35.71  ? 232 LEU B CD2 1 
ATOM   4169  N  N   . VAL B 1 233 ? -12.637 -16.721 -11.434 1.00 32.64  ? 233 VAL B N   1 
ATOM   4170  C  CA  . VAL B 1 233 ? -13.392 -15.800 -10.591 1.00 30.43  ? 233 VAL B CA  1 
ATOM   4171  C  C   . VAL B 1 233 ? -14.270 -14.908 -11.455 1.00 28.08  ? 233 VAL B C   1 
ATOM   4172  O  O   . VAL B 1 233 ? -15.451 -14.693 -11.156 1.00 26.77  ? 233 VAL B O   1 
ATOM   4173  C  CB  . VAL B 1 233 ? -12.436 -14.973 -9.715  1.00 34.15  ? 233 VAL B CB  1 
ATOM   4174  C  CG1 . VAL B 1 233 ? -13.213 -14.113 -8.724  1.00 29.66  ? 233 VAL B CG1 1 
ATOM   4175  C  CG2 . VAL B 1 233 ? -11.431 -15.881 -9.010  1.00 30.57  ? 233 VAL B CG2 1 
ATOM   4176  N  N   . ALA B 1 234 ? -13.708 -14.391 -12.551 1.00 27.59  ? 234 ALA B N   1 
ATOM   4177  C  CA  . ALA B 1 234 ? -14.448 -13.492 -13.430 1.00 29.69  ? 234 ALA B CA  1 
ATOM   4178  C  C   . ALA B 1 234 ? -15.716 -14.147 -13.967 1.00 30.02  ? 234 ALA B C   1 
ATOM   4179  O  O   . ALA B 1 234 ? -16.769 -13.508 -14.044 1.00 32.76  ? 234 ALA B O   1 
ATOM   4180  C  CB  . ALA B 1 234 ? -13.548 -13.053 -14.584 1.00 26.07  ? 234 ALA B CB  1 
ATOM   4181  N  N   . MET B 1 235 ? -15.642 -15.423 -14.337 1.00 29.82  ? 235 MET B N   1 
ATOM   4182  C  CA  . MET B 1 235 ? -16.822 -16.097 -14.866 1.00 32.25  ? 235 MET B CA  1 
ATOM   4183  C  C   . MET B 1 235 ? -17.945 -16.158 -13.833 1.00 31.58  ? 235 MET B C   1 
ATOM   4184  O  O   . MET B 1 235 ? -19.114 -15.938 -14.171 1.00 33.21  ? 235 MET B O   1 
ATOM   4185  C  CB  . MET B 1 235 ? -16.435 -17.496 -15.344 1.00 38.43  ? 235 MET B CB  1 
ATOM   4186  C  CG  . MET B 1 235 ? -17.593 -18.346 -15.833 1.00 51.72  ? 235 MET B CG  1 
ATOM   4187  S  SD  . MET B 1 235 ? -17.046 -19.964 -16.435 1.00 82.95  ? 235 MET B SD  1 
ATOM   4188  C  CE  . MET B 1 235 ? -16.639 -20.787 -14.891 1.00 56.91  ? 235 MET B CE  1 
ATOM   4189  N  N   . LYS B 1 236 ? -17.604 -16.412 -12.562 1.00 32.28  ? 236 LYS B N   1 
ATOM   4190  C  CA  . LYS B 1 236 ? -18.601 -16.439 -11.490 1.00 29.73  ? 236 LYS B CA  1 
ATOM   4191  C  C   . LYS B 1 236 ? -19.358 -15.126 -11.381 1.00 31.89  ? 236 LYS B C   1 
ATOM   4192  O  O   . LYS B 1 236 ? -20.498 -15.104 -10.902 1.00 35.07  ? 236 LYS B O   1 
ATOM   4193  C  CB  . LYS B 1 236 ? -17.940 -16.734 -10.149 1.00 24.47  ? 236 LYS B CB  1 
ATOM   4194  C  CG  . LYS B 1 236 ? -17.358 -18.111 -10.032 1.00 38.25  ? 236 LYS B CG  1 
ATOM   4195  C  CD  . LYS B 1 236 ? -16.430 -18.197 -8.828  1.00 40.65  ? 236 LYS B CD  1 
ATOM   4196  C  CE  . LYS B 1 236 ? -15.613 -19.483 -8.817  1.00 41.33  ? 236 LYS B CE  1 
ATOM   4197  N  NZ  . LYS B 1 236 ? -14.440 -19.257 -7.935  1.00 36.73  ? 236 LYS B NZ  1 
ATOM   4198  N  N   . TYR B 1 237 ? -18.710 -14.015 -11.728 1.00 32.41  ? 237 TYR B N   1 
ATOM   4199  C  CA  . TYR B 1 237 ? -19.277 -12.679 -11.627 1.00 28.92  ? 237 TYR B CA  1 
ATOM   4200  C  C   . TYR B 1 237 ? -19.749 -12.136 -12.962 1.00 30.42  ? 237 TYR B C   1 
ATOM   4201  O  O   . TYR B 1 237 ? -19.946 -10.921 -13.089 1.00 33.69  ? 237 TYR B O   1 
ATOM   4202  C  CB  . TYR B 1 237 ? -18.256 -11.724 -11.010 1.00 30.16  ? 237 TYR B CB  1 
ATOM   4203  C  CG  . TYR B 1 237 ? -18.004 -12.029 -9.570  1.00 28.18  ? 237 TYR B CG  1 
ATOM   4204  C  CD1 . TYR B 1 237 ? -17.084 -12.999 -9.201  1.00 24.46  ? 237 TYR B CD1 1 
ATOM   4205  C  CD2 . TYR B 1 237 ? -18.704 -11.366 -8.569  1.00 30.94  ? 237 TYR B CD2 1 
ATOM   4206  C  CE1 . TYR B 1 237 ? -16.856 -13.288 -7.882  1.00 26.85  ? 237 TYR B CE1 1 
ATOM   4207  C  CE2 . TYR B 1 237 ? -18.483 -11.658 -7.237  1.00 32.58  ? 237 TYR B CE2 1 
ATOM   4208  C  CZ  . TYR B 1 237 ? -17.561 -12.624 -6.900  1.00 27.97  ? 237 TYR B CZ  1 
ATOM   4209  O  OH  . TYR B 1 237 ? -17.329 -12.931 -5.572  1.00 31.05  ? 237 TYR B OH  1 
ATOM   4210  N  N   . ASN B 1 238 ? -19.891 -12.995 -13.968 1.00 29.00  ? 238 ASN B N   1 
ATOM   4211  C  CA  . ASN B 1 238 ? -20.444 -12.594 -15.263 1.00 30.24  ? 238 ASN B CA  1 
ATOM   4212  C  C   . ASN B 1 238 ? -19.583 -11.513 -15.922 1.00 26.40  ? 238 ASN B C   1 
ATOM   4213  O  O   . ASN B 1 238 ? -20.085 -10.619 -16.600 1.00 27.54  ? 238 ASN B O   1 
ATOM   4214  C  CB  . ASN B 1 238 ? -21.902 -12.134 -15.114 1.00 29.37  ? 238 ASN B CB  1 
ATOM   4215  C  CG  . ASN B 1 238 ? -22.688 -12.222 -16.416 1.00 33.93  ? 238 ASN B CG  1 
ATOM   4216  O  OD1 . ASN B 1 238 ? -22.385 -13.043 -17.285 1.00 39.07  ? 238 ASN B OD1 1 
ATOM   4217  N  ND2 . ASN B 1 238 ? -23.711 -11.381 -16.550 1.00 30.98  ? 238 ASN B ND2 1 
ATOM   4218  N  N   . TYR B 1 239 ? -18.270 -11.623 -15.742 1.00 28.28  ? 239 TYR B N   1 
ATOM   4219  C  CA  . TYR B 1 239 ? -17.288 -10.814 -16.442 1.00 22.12  ? 239 TYR B CA  1 
ATOM   4220  C  C   . TYR B 1 239 ? -16.818 -11.531 -17.697 1.00 26.92  ? 239 TYR B C   1 
ATOM   4221  O  O   . TYR B 1 239 ? -16.686 -12.757 -17.711 1.00 28.15  ? 239 TYR B O   1 
ATOM   4222  C  CB  . TYR B 1 239 ? -16.088 -10.536 -15.540 1.00 22.23  ? 239 TYR B CB  1 
ATOM   4223  C  CG  . TYR B 1 239 ? -16.193 -9.294  -14.669 1.00 23.70  ? 239 TYR B CG  1 
ATOM   4224  C  CD1 . TYR B 1 239 ? -17.270 -9.105  -13.817 1.00 22.08  ? 239 TYR B CD1 1 
ATOM   4225  C  CD2 . TYR B 1 239 ? -15.181 -8.323  -14.678 1.00 22.69  ? 239 TYR B CD2 1 
ATOM   4226  C  CE1 . TYR B 1 239 ? -17.357 -7.961  -13.003 1.00 27.18  ? 239 TYR B CE1 1 
ATOM   4227  C  CE2 . TYR B 1 239 ? -15.256 -7.195  -13.878 1.00 24.54  ? 239 TYR B CE2 1 
ATOM   4228  C  CZ  . TYR B 1 239 ? -16.346 -7.010  -13.046 1.00 25.02  ? 239 TYR B CZ  1 
ATOM   4229  O  OH  . TYR B 1 239 ? -16.423 -5.881  -12.261 1.00 23.30  ? 239 TYR B OH  1 
ATOM   4230  N  N   A GLU B 1 240 ? -16.608 -10.759 -18.767 0.52 30.30  ? 240 GLU B N   1 
ATOM   4231  N  N   B GLU B 1 240 ? -16.589 -10.759 -18.762 0.48 30.25  ? 240 GLU B N   1 
ATOM   4232  C  CA  A GLU B 1 240 ? -16.118 -11.341 -20.041 0.52 30.30  ? 240 GLU B CA  1 
ATOM   4233  C  CA  B GLU B 1 240 ? -16.121 -11.340 -20.045 0.48 30.34  ? 240 GLU B CA  1 
ATOM   4234  C  C   A GLU B 1 240 ? -14.734 -11.938 -19.822 0.52 28.20  ? 240 GLU B C   1 
ATOM   4235  C  C   B GLU B 1 240 ? -14.714 -11.912 -19.878 0.48 28.06  ? 240 GLU B C   1 
ATOM   4236  O  O   A GLU B 1 240 ? -13.953 -11.383 -19.046 0.52 25.80  ? 240 GLU B O   1 
ATOM   4237  O  O   B GLU B 1 240 ? -13.960 -11.374 -19.063 0.48 24.81  ? 240 GLU B O   1 
ATOM   4238  C  CB  A GLU B 1 240 ? -16.009 -10.265 -21.124 0.52 29.83  ? 240 GLU B CB  1 
ATOM   4239  C  CB  B GLU B 1 240 ? -16.121 -10.252 -21.122 0.48 29.80  ? 240 GLU B CB  1 
ATOM   4240  C  CG  A GLU B 1 240 ? -17.285 -10.046 -21.908 0.52 30.90  ? 240 GLU B CG  1 
ATOM   4241  C  CG  B GLU B 1 240 ? -15.993 -10.786 -22.532 0.48 30.50  ? 240 GLU B CG  1 
ATOM   4242  C  CD  A GLU B 1 240 ? -17.695 -11.205 -22.797 0.52 33.57  ? 240 GLU B CD  1 
ATOM   4243  C  CD  B GLU B 1 240 ? -17.245 -11.476 -23.042 0.48 33.28  ? 240 GLU B CD  1 
ATOM   4244  O  OE1 A GLU B 1 240 ? -16.799 -11.869 -23.350 0.52 33.69  ? 240 GLU B OE1 1 
ATOM   4245  O  OE1 B GLU B 1 240 ? -18.350 -10.982 -22.752 0.48 34.19  ? 240 GLU B OE1 1 
ATOM   4246  O  OE2 A GLU B 1 240 ? -18.909 -11.438 -22.934 0.52 32.30  ? 240 GLU B OE2 1 
ATOM   4247  O  OE2 B GLU B 1 240 ? -17.109 -12.505 -23.726 0.48 33.04  ? 240 GLU B OE2 1 
ATOM   4248  N  N   . PRO B 1 241 ? -14.490 -13.172 -20.304 1.00 29.26  ? 241 PRO B N   1 
ATOM   4249  C  CA  . PRO B 1 241 ? -13.169 -13.802 -20.161 1.00 26.42  ? 241 PRO B CA  1 
ATOM   4250  C  C   . PRO B 1 241 ? -12.093 -12.894 -20.717 1.00 27.36  ? 241 PRO B C   1 
ATOM   4251  O  O   . PRO B 1 241 ? -12.257 -12.278 -21.777 1.00 29.11  ? 241 PRO B O   1 
ATOM   4252  C  CB  . PRO B 1 241 ? -13.307 -15.086 -20.991 1.00 24.94  ? 241 PRO B CB  1 
ATOM   4253  C  CG  . PRO B 1 241 ? -14.780 -15.329 -21.064 1.00 28.68  ? 241 PRO B CG  1 
ATOM   4254  C  CD  . PRO B 1 241 ? -15.425 -13.992 -21.077 1.00 29.19  ? 241 PRO B CD  1 
ATOM   4255  N  N   . LEU B 1 242 ? -10.999 -12.788 -19.969 1.00 26.70  ? 242 LEU B N   1 
ATOM   4256  C  CA  . LEU B 1 242 ? -9.858  -11.977 -20.373 1.00 29.66  ? 242 LEU B CA  1 
ATOM   4257  C  C   . LEU B 1 242 ? -8.907  -12.807 -21.232 1.00 26.05  ? 242 LEU B C   1 
ATOM   4258  O  O   . LEU B 1 242 ? -8.474  -13.886 -20.823 1.00 31.44  ? 242 LEU B O   1 
ATOM   4259  C  CB  . LEU B 1 242 ? -9.120  -11.437 -19.145 1.00 23.98  ? 242 LEU B CB  1 
ATOM   4260  C  CG  . LEU B 1 242 ? -8.189  -10.253 -19.414 1.00 24.29  ? 242 LEU B CG  1 
ATOM   4261  C  CD1 . LEU B 1 242 ? -8.992  -8.979  -19.616 1.00 24.49  ? 242 LEU B CD1 1 
ATOM   4262  C  CD2 . LEU B 1 242 ? -7.158  -10.090 -18.319 1.00 27.67  ? 242 LEU B CD2 1 
ATOM   4263  N  N   . THR B 1 243 ? -8.563  -12.289 -22.397 1.00 23.92  ? 243 THR B N   1 
ATOM   4264  C  CA  . THR B 1 243 ? -7.692  -12.980 -23.330 1.00 23.56  ? 243 THR B CA  1 
ATOM   4265  C  C   . THR B 1 243 ? -6.326  -12.310 -23.329 1.00 27.61  ? 243 THR B C   1 
ATOM   4266  O  O   . THR B 1 243 ? -6.133  -11.247 -22.726 1.00 30.97  ? 243 THR B O   1 
ATOM   4267  C  CB  . THR B 1 243 ? -8.286  -12.964 -24.732 1.00 27.56  ? 243 THR B CB  1 
ATOM   4268  O  OG1 . THR B 1 243 ? -8.189  -11.643 -25.265 1.00 25.38  ? 243 THR B OG1 1 
ATOM   4269  C  CG2 . THR B 1 243 ? -9.764  -13.349 -24.665 1.00 21.74  ? 243 THR B CG2 1 
ATOM   4270  N  N   . GLN B 1 244 ? -5.359  -12.972 -23.968 1.00 22.13  ? 244 GLN B N   1 
ATOM   4271  C  CA  . GLN B 1 244 ? -4.030  -12.383 -24.107 1.00 31.34  ? 244 GLN B CA  1 
ATOM   4272  C  C   . GLN B 1 244 ? -4.073  -11.126 -24.974 1.00 29.53  ? 244 GLN B C   1 
ATOM   4273  O  O   . GLN B 1 244 ? -3.290  -10.200 -24.753 1.00 27.57  ? 244 GLN B O   1 
ATOM   4274  C  CB  . GLN B 1 244 ? -3.037  -13.425 -24.663 1.00 30.78  ? 244 GLN B CB  1 
ATOM   4275  C  CG  . GLN B 1 244 ? -1.549  -12.967 -24.772 1.00 32.18  ? 244 GLN B CG  1 
ATOM   4276  C  CD  . GLN B 1 244 ? -0.904  -12.553 -23.440 1.00 30.08  ? 244 GLN B CD  1 
ATOM   4277  O  OE1 . GLN B 1 244 ? -1.160  -13.141 -22.385 1.00 31.10  ? 244 GLN B OE1 1 
ATOM   4278  N  NE2 . GLN B 1 244 ? -0.060  -11.536 -23.495 1.00 28.93  ? 244 GLN B NE2 1 
ATOM   4279  N  N   . ASP B 1 245 ? -4.971  -11.079 -25.962 1.00 27.63  ? 245 ASP B N   1 
ATOM   4280  C  CA  . ASP B 1 245 ? -5.187  -9.839  -26.708 1.00 33.18  ? 245 ASP B CA  1 
ATOM   4281  C  C   . ASP B 1 245 ? -5.602  -8.703  -25.786 1.00 29.83  ? 245 ASP B C   1 
ATOM   4282  O  O   . ASP B 1 245 ? -5.176  -7.555  -25.974 1.00 29.69  ? 245 ASP B O   1 
ATOM   4283  C  CB  . ASP B 1 245 ? -6.224  -10.054 -27.809 1.00 30.76  ? 245 ASP B CB  1 
ATOM   4284  C  CG  . ASP B 1 245 ? -5.592  -10.527 -29.109 1.00 46.00  ? 245 ASP B CG  1 
ATOM   4285  O  OD1 . ASP B 1 245 ? -4.415  -10.974 -29.088 1.00 50.34  ? 245 ASP B OD1 1 
ATOM   4286  O  OD2 . ASP B 1 245 ? -6.285  -10.487 -30.148 1.00 57.02  ? 245 ASP B OD2 1 
ATOM   4287  N  N   . HIS B 1 246 ? -6.430  -9.005  -24.782 1.00 25.01  ? 246 HIS B N   1 
ATOM   4288  C  CA  . HIS B 1 246 ? -6.806  -7.994  -23.799 1.00 26.62  ? 246 HIS B CA  1 
ATOM   4289  C  C   . HIS B 1 246 ? -5.602  -7.545  -22.978 1.00 28.95  ? 246 HIS B C   1 
ATOM   4290  O  O   . HIS B 1 246 ? -5.407  -6.338  -22.767 1.00 27.91  ? 246 HIS B O   1 
ATOM   4291  C  CB  . HIS B 1 246 ? -7.908  -8.533  -22.898 1.00 26.71  ? 246 HIS B CB  1 
ATOM   4292  C  CG  . HIS B 1 246 ? -9.239  -8.625  -23.572 1.00 27.58  ? 246 HIS B CG  1 
ATOM   4293  N  ND1 . HIS B 1 246 ? -10.178 -9.582  -23.246 1.00 30.04  ? 246 HIS B ND1 1 
ATOM   4294  C  CD2 . HIS B 1 246 ? -9.785  -7.877  -24.559 1.00 27.06  ? 246 HIS B CD2 1 
ATOM   4295  C  CE1 . HIS B 1 246 ? -11.251 -9.412  -23.998 1.00 28.96  ? 246 HIS B CE1 1 
ATOM   4296  N  NE2 . HIS B 1 246 ? -11.036 -8.387  -24.806 1.00 31.77  ? 246 HIS B NE2 1 
ATOM   4297  N  N   . VAL B 1 247 ? -4.780  -8.502  -22.522 1.00 27.90  ? 247 VAL B N   1 
ATOM   4298  C  CA  . VAL B 1 247 ? -3.524  -8.188  -21.837 1.00 26.88  ? 247 VAL B CA  1 
ATOM   4299  C  C   . VAL B 1 247 ? -2.633  -7.323  -22.721 1.00 28.28  ? 247 VAL B C   1 
ATOM   4300  O  O   . VAL B 1 247 ? -2.016  -6.358  -22.250 1.00 29.59  ? 247 VAL B O   1 
ATOM   4301  C  CB  . VAL B 1 247 ? -2.791  -9.478  -21.407 1.00 28.59  ? 247 VAL B CB  1 
ATOM   4302  C  CG1 . VAL B 1 247 ? -1.478  -9.142  -20.707 1.00 24.94  ? 247 VAL B CG1 1 
ATOM   4303  C  CG2 . VAL B 1 247 ? -3.672  -10.350 -20.524 1.00 25.49  ? 247 VAL B CG2 1 
ATOM   4304  N  N   . ASP B 1 248 ? -2.514  -7.670  -24.003 1.00 26.60  ? 248 ASP B N   1 
ATOM   4305  C  CA  . ASP B 1 248 ? -1.682  -6.856  -24.890 1.00 31.01  ? 248 ASP B CA  1 
ATOM   4306  C  C   . ASP B 1 248 ? -2.237  -5.437  -25.025 1.00 24.01  ? 248 ASP B C   1 
ATOM   4307  O  O   . ASP B 1 248 ? -1.478  -4.463  -24.992 1.00 25.79  ? 248 ASP B O   1 
ATOM   4308  C  CB  . ASP B 1 248 ? -1.543  -7.518  -26.263 1.00 29.44  ? 248 ASP B CB  1 
ATOM   4309  C  CG  . ASP B 1 248 ? -0.867  -8.902  -26.199 1.00 33.22  ? 248 ASP B CG  1 
ATOM   4310  O  OD1 . ASP B 1 248 ? -0.031  -9.161  -25.290 1.00 27.47  ? 248 ASP B OD1 1 
ATOM   4311  O  OD2 . ASP B 1 248 ? -1.175  -9.735  -27.083 1.00 36.79  ? 248 ASP B OD2 1 
ATOM   4312  N  N   . ILE B 1 249 ? -3.563  -5.304  -25.140 1.00 27.61  ? 249 ILE B N   1 
ATOM   4313  C  CA  . ILE B 1 249 ? -4.200  -3.993  -25.288 1.00 28.12  ? 249 ILE B CA  1 
ATOM   4314  C  C   . ILE B 1 249 ? -3.927  -3.126  -24.065 1.00 25.38  ? 249 ILE B C   1 
ATOM   4315  O  O   . ILE B 1 249 ? -3.712  -1.909  -24.178 1.00 28.49  ? 249 ILE B O   1 
ATOM   4316  C  CB  . ILE B 1 249 ? -5.712  -4.184  -25.565 1.00 30.23  ? 249 ILE B CB  1 
ATOM   4317  C  CG1 . ILE B 1 249 ? -5.916  -4.636  -27.020 1.00 25.93  ? 249 ILE B CG1 1 
ATOM   4318  C  CG2 . ILE B 1 249 ? -6.539  -2.946  -25.251 1.00 24.04  ? 249 ILE B CG2 1 
ATOM   4319  C  CD1 . ILE B 1 249 ? -7.247  -5.269  -27.282 1.00 28.46  ? 249 ILE B CD1 1 
ATOM   4320  N  N   . LEU B 1 250 ? -3.890  -3.743  -22.883 1.00 28.66  ? 250 LEU B N   1 
ATOM   4321  C  CA  . LEU B 1 250 ? -3.581  -3.061  -21.627 1.00 28.69  ? 250 LEU B CA  1 
ATOM   4322  C  C   . LEU B 1 250 ? -2.105  -2.739  -21.449 1.00 23.32  ? 250 LEU B C   1 
ATOM   4323  O  O   . LEU B 1 250 ? -1.759  -2.112  -20.450 1.00 28.10  ? 250 LEU B O   1 
ATOM   4324  C  CB  . LEU B 1 250 ? -4.047  -3.917  -20.451 1.00 23.63  ? 250 LEU B CB  1 
ATOM   4325  C  CG  . LEU B 1 250 ? -5.562  -3.948  -20.285 1.00 21.49  ? 250 LEU B CG  1 
ATOM   4326  C  CD1 . LEU B 1 250 ? -5.952  -5.099  -19.378 1.00 17.65  ? 250 LEU B CD1 1 
ATOM   4327  C  CD2 . LEU B 1 250 ? -6.047  -2.630  -19.729 1.00 20.85  ? 250 LEU B CD2 1 
ATOM   4328  N  N   . GLY B 1 251 ? -1.238  -3.161  -22.368 1.00 25.23  ? 251 GLY B N   1 
ATOM   4329  C  CA  . GLY B 1 251 ? 0.186   -2.909  -22.299 1.00 27.10  ? 251 GLY B CA  1 
ATOM   4330  C  C   . GLY B 1 251 ? 0.606   -1.463  -22.029 1.00 27.49  ? 251 GLY B C   1 
ATOM   4331  O  O   . GLY B 1 251 ? 1.378   -1.193  -21.097 1.00 24.91  ? 251 GLY B O   1 
ATOM   4332  N  N   . PRO B 1 252 ? 0.143   -0.511  -22.856 1.00 24.79  ? 252 PRO B N   1 
ATOM   4333  C  CA  . PRO B 1 252 ? 0.550   0.886   -22.634 1.00 23.20  ? 252 PRO B CA  1 
ATOM   4334  C  C   . PRO B 1 252 ? 0.223   1.391   -21.243 1.00 26.30  ? 252 PRO B C   1 
ATOM   4335  O  O   . PRO B 1 252 ? 1.035   2.109   -20.646 1.00 25.09  ? 252 PRO B O   1 
ATOM   4336  C  CB  . PRO B 1 252 ? -0.223  1.650   -23.711 1.00 19.29  ? 252 PRO B CB  1 
ATOM   4337  C  CG  . PRO B 1 252 ? -0.450  0.669   -24.791 1.00 18.47  ? 252 PRO B CG  1 
ATOM   4338  C  CD  . PRO B 1 252 ? -0.657  -0.654  -24.085 1.00 22.76  ? 252 PRO B CD  1 
ATOM   4339  N  N   . LEU B 1 253 ? -0.958  1.052   -20.716 1.00 24.52  ? 253 LEU B N   1 
ATOM   4340  C  CA  . LEU B 1 253 ? -1.320  1.477   -19.367 1.00 23.77  ? 253 LEU B CA  1 
ATOM   4341  C  C   . LEU B 1 253 ? -0.506  0.747   -18.310 1.00 25.95  ? 253 LEU B C   1 
ATOM   4342  O  O   . LEU B 1 253 ? -0.226  1.311   -17.241 1.00 22.92  ? 253 LEU B O   1 
ATOM   4343  C  CB  . LEU B 1 253 ? -2.819  1.284   -19.130 1.00 20.95  ? 253 LEU B CB  1 
ATOM   4344  C  CG  . LEU B 1 253 ? -3.760  2.278   -19.807 1.00 21.98  ? 253 LEU B CG  1 
ATOM   4345  C  CD1 . LEU B 1 253 ? -5.234  1.882   -19.609 1.00 21.21  ? 253 LEU B CD1 1 
ATOM   4346  C  CD2 . LEU B 1 253 ? -3.516  3.678   -19.243 1.00 18.86  ? 253 LEU B CD2 1 
ATOM   4347  N  N   . SER B 1 254 ? -0.146  -0.510  -18.581 1.00 23.92  ? 254 SER B N   1 
ATOM   4348  C  CA  . SER B 1 254 ? 0.694   -1.266  -17.658 1.00 25.06  ? 254 SER B CA  1 
ATOM   4349  C  C   . SER B 1 254 ? 2.083   -0.655  -17.518 1.00 28.89  ? 254 SER B C   1 
ATOM   4350  O  O   . SER B 1 254 ? 2.647   -0.630  -16.416 1.00 23.43  ? 254 SER B O   1 
ATOM   4351  C  CB  . SER B 1 254 ? 0.836   -2.706  -18.132 1.00 24.62  ? 254 SER B CB  1 
ATOM   4352  O  OG  . SER B 1 254 ? 1.801   -3.364  -17.332 1.00 26.51  ? 254 SER B OG  1 
ATOM   4353  N  N   . ALA B 1 255 ? 2.676   -0.218  -18.636 1.00 24.31  ? 255 ALA B N   1 
ATOM   4354  C  CA  . ALA B 1 255 ? 4.022   0.335   -18.587 1.00 22.04  ? 255 ALA B CA  1 
ATOM   4355  C  C   . ALA B 1 255 ? 4.029   1.707   -17.918 1.00 24.43  ? 255 ALA B C   1 
ATOM   4356  O  O   . ALA B 1 255 ? 4.916   2.013   -17.111 1.00 28.16  ? 255 ALA B O   1 
ATOM   4357  C  CB  . ALA B 1 255 ? 4.601   0.387   -19.998 1.00 20.81  ? 255 ALA B CB  1 
ATOM   4358  N  N   . GLN B 1 256 ? 3.010   2.518   -18.179 1.00 26.23  ? 256 GLN B N   1 
ATOM   4359  C  CA  . GLN B 1 256 ? 2.964   3.846   -17.584 1.00 27.40  ? 256 GLN B CA  1 
ATOM   4360  C  C   . GLN B 1 256 ? 2.917   3.797   -16.061 1.00 31.20  ? 256 GLN B C   1 
ATOM   4361  O  O   . GLN B 1 256 ? 3.524   4.644   -15.395 1.00 28.97  ? 256 GLN B O   1 
ATOM   4362  C  CB  . GLN B 1 256 ? 1.762   4.597   -18.135 1.00 30.23  ? 256 GLN B CB  1 
ATOM   4363  C  CG  . GLN B 1 256 ? 1.419   5.856   -17.383 1.00 32.49  ? 256 GLN B CG  1 
ATOM   4364  C  CD  . GLN B 1 256 ? 0.430   6.697   -18.154 1.00 32.34  ? 256 GLN B CD  1 
ATOM   4365  O  OE1 . GLN B 1 256 ? 0.030   6.333   -19.270 1.00 29.40  ? 256 GLN B OE1 1 
ATOM   4366  N  NE2 . GLN B 1 256 ? 0.012   7.822   -17.562 1.00 31.13  ? 256 GLN B NE2 1 
ATOM   4367  N  N   . THR B 1 257 ? 2.251   2.795   -15.484 1.00 26.42  ? 257 THR B N   1 
ATOM   4368  C  CA  . THR B 1 257 ? 2.187   2.674   -14.034 1.00 22.75  ? 257 THR B CA  1 
ATOM   4369  C  C   . THR B 1 257 ? 3.233   1.716   -13.461 1.00 26.13  ? 257 THR B C   1 
ATOM   4370  O  O   . THR B 1 257 ? 3.562   1.822   -12.275 1.00 26.21  ? 257 THR B O   1 
ATOM   4371  C  CB  . THR B 1 257 ? 0.773   2.218   -13.588 1.00 28.57  ? 257 THR B CB  1 
ATOM   4372  O  OG1 . THR B 1 257 ? 0.420   0.961   -14.191 1.00 19.53  ? 257 THR B OG1 1 
ATOM   4373  C  CG2 . THR B 1 257 ? -0.282  3.265   -13.974 1.00 25.75  ? 257 THR B CG2 1 
ATOM   4374  N  N   . GLY B 1 258 ? 3.789   0.804   -14.258 1.00 21.75  ? 258 GLY B N   1 
ATOM   4375  C  CA  . GLY B 1 258 ? 4.666   -0.189  -13.674 1.00 20.11  ? 258 GLY B CA  1 
ATOM   4376  C  C   . GLY B 1 258 ? 3.968   -1.274  -12.880 1.00 28.45  ? 258 GLY B C   1 
ATOM   4377  O  O   . GLY B 1 258 ? 4.583   -1.884  -11.994 1.00 33.04  ? 258 GLY B O   1 
ATOM   4378  N  N   . ILE B 1 259 ? 2.686   -1.523  -13.143 1.00 32.42  ? 259 ILE B N   1 
ATOM   4379  C  CA  . ILE B 1 259 ? 1.960   -2.638  -12.535 1.00 24.45  ? 259 ILE B CA  1 
ATOM   4380  C  C   . ILE B 1 259 ? 1.618   -3.633  -13.639 1.00 24.56  ? 259 ILE B C   1 
ATOM   4381  O  O   . ILE B 1 259 ? 0.834   -3.325  -14.547 1.00 27.91  ? 259 ILE B O   1 
ATOM   4382  C  CB  . ILE B 1 259 ? 0.701   -2.164  -11.802 1.00 22.04  ? 259 ILE B CB  1 
ATOM   4383  C  CG1 . ILE B 1 259 ? 1.096   -1.202  -10.682 1.00 18.85  ? 259 ILE B CG1 1 
ATOM   4384  C  CG2 . ILE B 1 259 ? -0.119  -3.385  -11.293 1.00 24.98  ? 259 ILE B CG2 1 
ATOM   4385  C  CD1 . ILE B 1 259 ? -0.041  -0.452  -10.125 1.00 21.48  ? 259 ILE B CD1 1 
ATOM   4386  N  N   . ALA B 1 260 ? 2.185   -4.834  -13.560 1.00 25.11  ? 260 ALA B N   1 
ATOM   4387  C  CA  . ALA B 1 260 ? 1.900   -5.845  -14.567 1.00 24.24  ? 260 ALA B CA  1 
ATOM   4388  C  C   . ALA B 1 260 ? 0.404   -6.140  -14.582 1.00 22.48  ? 260 ALA B C   1 
ATOM   4389  O  O   . ALA B 1 260 ? -0.292  -5.966  -13.579 1.00 21.07  ? 260 ALA B O   1 
ATOM   4390  C  CB  . ALA B 1 260 ? 2.699   -7.125  -14.288 1.00 20.33  ? 260 ALA B CB  1 
ATOM   4391  N  N   . VAL B 1 261 ? -0.089  -6.530  -15.759 1.00 23.08  ? 261 VAL B N   1 
ATOM   4392  C  CA  . VAL B 1 261 ? -1.521  -6.722  -15.974 1.00 23.04  ? 261 VAL B CA  1 
ATOM   4393  C  C   . VAL B 1 261 ? -2.051  -7.831  -15.070 1.00 24.35  ? 261 VAL B C   1 
ATOM   4394  O  O   . VAL B 1 261 ? -3.136  -7.718  -14.496 1.00 26.33  ? 261 VAL B O   1 
ATOM   4395  C  CB  . VAL B 1 261 ? -1.791  -6.997  -17.472 1.00 24.56  ? 261 VAL B CB  1 
ATOM   4396  C  CG1 . VAL B 1 261 ? -3.231  -7.439  -17.744 1.00 22.63  ? 261 VAL B CG1 1 
ATOM   4397  C  CG2 . VAL B 1 261 ? -1.428  -5.765  -18.316 1.00 19.21  ? 261 VAL B CG2 1 
ATOM   4398  N  N   . LEU B 1 262 ? -1.293  -8.911  -14.917 1.00 22.24  ? 262 LEU B N   1 
ATOM   4399  C  CA  . LEU B 1 262 ? -1.729  -9.994  -14.040 1.00 26.60  ? 262 LEU B CA  1 
ATOM   4400  C  C   . LEU B 1 262 ? -1.673  -9.598  -12.568 1.00 28.70  ? 262 LEU B C   1 
ATOM   4401  O  O   . LEU B 1 262 ? -2.413  -10.165 -11.742 1.00 24.29  ? 262 LEU B O   1 
ATOM   4402  C  CB  . LEU B 1 262 ? -0.886  -11.239 -14.305 1.00 23.61  ? 262 LEU B CB  1 
ATOM   4403  C  CG  . LEU B 1 262 ? -1.177  -11.828 -15.682 1.00 22.83  ? 262 LEU B CG  1 
ATOM   4404  C  CD1 . LEU B 1 262 ? -0.252  -13.012 -15.980 1.00 21.35  ? 262 LEU B CD1 1 
ATOM   4405  C  CD2 . LEU B 1 262 ? -2.644  -12.221 -15.793 1.00 24.10  ? 262 LEU B CD2 1 
ATOM   4406  N  N   . ASP B 1 263 ? -0.807  -8.640  -12.216 1.00 22.39  ? 263 ASP B N   1 
ATOM   4407  C  CA  . ASP B 1 263 ? -0.840  -8.085  -10.865 1.00 21.85  ? 263 ASP B CA  1 
ATOM   4408  C  C   . ASP B 1 263 ? -2.133  -7.298  -10.635 1.00 22.83  ? 263 ASP B C   1 
ATOM   4409  O  O   . ASP B 1 263 ? -2.781  -7.448  -9.589  1.00 21.80  ? 263 ASP B O   1 
ATOM   4410  C  CB  . ASP B 1 263 ? 0.382   -7.187  -10.633 1.00 24.48  ? 263 ASP B CB  1 
ATOM   4411  C  CG  . ASP B 1 263 ? 1.714   -7.965  -10.592 1.00 30.96  ? 263 ASP B CG  1 
ATOM   4412  O  OD1 . ASP B 1 263 ? 1.738   -9.205  -10.795 1.00 30.05  ? 263 ASP B OD1 1 
ATOM   4413  O  OD2 . ASP B 1 263 ? 2.756   -7.324  -10.334 1.00 25.72  ? 263 ASP B OD2 1 
ATOM   4414  N  N   . MET B 1 264 ? -2.530  -6.469  -11.620 1.00 21.46  ? 264 MET B N   1 
ATOM   4415  C  CA  . MET B 1 264 ? -3.795  -5.742  -11.548 1.00 19.15  ? 264 MET B CA  1 
ATOM   4416  C  C   . MET B 1 264 ? -4.988  -6.686  -11.564 1.00 18.71  ? 264 MET B C   1 
ATOM   4417  O  O   . MET B 1 264 ? -6.033  -6.393  -10.960 1.00 18.23  ? 264 MET B O   1 
ATOM   4418  C  CB  . MET B 1 264 ? -3.907  -4.750  -12.711 1.00 18.02  ? 264 MET B CB  1 
ATOM   4419  C  CG  . MET B 1 264 ? -5.122  -3.826  -12.609 1.00 15.83  ? 264 MET B CG  1 
ATOM   4420  S  SD  . MET B 1 264 ? -5.035  -2.697  -11.171 1.00 25.42  ? 264 MET B SD  1 
ATOM   4421  C  CE  . MET B 1 264 ? -3.893  -1.431  -11.788 1.00 21.34  ? 264 MET B CE  1 
ATOM   4422  N  N   . CYS B 1 265 ? -4.884  -7.784  -12.324 1.00 16.18  ? 265 CYS B N   1 
ATOM   4423  C  CA  . CYS B 1 265 ? -5.926  -8.802  -12.286 1.00 21.26  ? 265 CYS B CA  1 
ATOM   4424  C  C   . CYS B 1 265 ? -6.087  -9.357  -10.871 1.00 19.76  ? 265 CYS B C   1 
ATOM   4425  O  O   . CYS B 1 265 ? -7.211  -9.610  -10.415 1.00 20.80  ? 265 CYS B O   1 
ATOM   4426  C  CB  . CYS B 1 265 ? -5.600  -9.931  -13.272 1.00 18.48  ? 265 CYS B CB  1 
ATOM   4427  S  SG  . CYS B 1 265 ? -5.824  -9.490  -14.997 1.00 20.09  ? 265 CYS B SG  1 
ATOM   4428  N  N   . ALA B 1 266 ? -4.976  -9.532  -10.152 1.00 17.18  ? 266 ALA B N   1 
ATOM   4429  C  CA  . ALA B 1 266 ? -5.077  -10.005 -8.776  1.00 23.06  ? 266 ALA B CA  1 
ATOM   4430  C  C   . ALA B 1 266 ? -5.800  -8.994  -7.894  1.00 23.30  ? 266 ALA B C   1 
ATOM   4431  O  O   . ALA B 1 266 ? -6.518  -9.390  -6.964  1.00 23.63  ? 266 ALA B O   1 
ATOM   4432  C  CB  . ALA B 1 266 ? -3.692  -10.339 -8.210  1.00 15.70  ? 266 ALA B CB  1 
ATOM   4433  N  N   . SER B 1 267 ? -5.644  -7.692  -8.166  1.00 19.47  ? 267 SER B N   1 
ATOM   4434  C  CA  . SER B 1 267 ? -6.405  -6.722  -7.392  1.00 19.77  ? 267 SER B CA  1 
ATOM   4435  C  C   . SER B 1 267 ? -7.870  -6.763  -7.758  1.00 21.63  ? 267 SER B C   1 
ATOM   4436  O  O   . SER B 1 267 ? -8.736  -6.652  -6.883  1.00 22.87  ? 267 SER B O   1 
ATOM   4437  C  CB  . SER B 1 267 ? -5.852  -5.315  -7.576  1.00 26.26  ? 267 SER B CB  1 
ATOM   4438  O  OG  . SER B 1 267 ? -4.664  -5.173  -6.825  1.00 29.42  ? 267 SER B OG  1 
ATOM   4439  N  N   . LEU B 1 268 ? -8.174  -6.904  -9.050  1.00 21.38  ? 268 LEU B N   1 
ATOM   4440  C  CA  . LEU B 1 268 ? -9.572  -6.991  -9.456  1.00 20.66  ? 268 LEU B CA  1 
ATOM   4441  C  C   . LEU B 1 268 ? -10.238 -8.244  -8.884  1.00 21.93  ? 268 LEU B C   1 
ATOM   4442  O  O   . LEU B 1 268 ? -11.388 -8.198  -8.416  1.00 22.59  ? 268 LEU B O   1 
ATOM   4443  C  CB  . LEU B 1 268 ? -9.662  -6.968  -10.976 1.00 18.16  ? 268 LEU B CB  1 
ATOM   4444  C  CG  . LEU B 1 268 ? -11.067 -7.105  -11.537 1.00 15.60  ? 268 LEU B CG  1 
ATOM   4445  C  CD1 . LEU B 1 268 ? -11.958 -6.029  -10.946 1.00 12.72  ? 268 LEU B CD1 1 
ATOM   4446  C  CD2 . LEU B 1 268 ? -11.002 -7.032  -13.049 1.00 18.21  ? 268 LEU B CD2 1 
ATOM   4447  N  N   . LYS B 1 269 ? -9.528  -9.371  -8.923  1.00 20.40  ? 269 LYS B N   1 
ATOM   4448  C  CA  . LYS B 1 269 ? -10.016 -10.613 -8.320  1.00 25.00  ? 269 LYS B CA  1 
ATOM   4449  C  C   . LYS B 1 269 ? -10.399 -10.409 -6.854  1.00 26.30  ? 269 LYS B C   1 
ATOM   4450  O  O   . LYS B 1 269 ? -11.445 -10.888 -6.398  1.00 27.13  ? 269 LYS B O   1 
ATOM   4451  C  CB  . LYS B 1 269 ? -8.943  -11.692 -8.468  1.00 27.56  ? 269 LYS B CB  1 
ATOM   4452  C  CG  . LYS B 1 269 ? -9.241  -13.006 -7.820  1.00 41.04  ? 269 LYS B CG  1 
ATOM   4453  C  CD  . LYS B 1 269 ? -8.382  -14.119 -8.428  1.00 36.35  ? 269 LYS B CD  1 
ATOM   4454  C  CE  . LYS B 1 269 ? -8.056  -15.188 -7.371  1.00 45.33  ? 269 LYS B CE  1 
ATOM   4455  N  NZ  . LYS B 1 269 ? -6.899  -16.085 -7.753  1.00 49.25  ? 269 LYS B NZ  1 
ATOM   4456  N  N   . GLU B 1 270 ? -9.566  -9.693  -6.097  1.00 24.26  ? 270 GLU B N   1 
ATOM   4457  C  CA  . GLU B 1 270 ? -9.889  -9.452  -4.696  1.00 30.09  ? 270 GLU B CA  1 
ATOM   4458  C  C   . GLU B 1 270 ? -11.048 -8.476  -4.549  1.00 27.72  ? 270 GLU B C   1 
ATOM   4459  O  O   . GLU B 1 270 ? -11.919 -8.676  -3.698  1.00 25.33  ? 270 GLU B O   1 
ATOM   4460  C  CB  . GLU B 1 270 ? -8.652  -8.960  -3.944  1.00 31.65  ? 270 GLU B CB  1 
ATOM   4461  C  CG  . GLU B 1 270 ? -7.616  -10.061 -3.820  1.00 37.73  ? 270 GLU B CG  1 
ATOM   4462  C  CD  . GLU B 1 270 ? -8.164  -11.283 -3.086  1.00 44.33  ? 270 GLU B CD  1 
ATOM   4463  O  OE1 . GLU B 1 270 ? -8.672  -11.118 -1.952  1.00 50.28  ? 270 GLU B OE1 1 
ATOM   4464  O  OE2 . GLU B 1 270 ? -8.148  -12.392 -3.673  1.00 43.54  ? 270 GLU B OE2 1 
ATOM   4465  N  N   . LEU B 1 271 ? -11.099 -7.436  -5.388  1.00 25.01  ? 271 LEU B N   1 
ATOM   4466  C  CA  . LEU B 1 271 ? -12.249 -6.534  -5.370  1.00 25.76  ? 271 LEU B CA  1 
ATOM   4467  C  C   . LEU B 1 271 ? -13.550 -7.281  -5.649  1.00 25.55  ? 271 LEU B C   1 
ATOM   4468  O  O   . LEU B 1 271 ? -14.546 -7.096  -4.939  1.00 18.78  ? 271 LEU B O   1 
ATOM   4469  C  CB  . LEU B 1 271 ? -12.054 -5.413  -6.388  1.00 19.32  ? 271 LEU B CB  1 
ATOM   4470  C  CG  . LEU B 1 271 ? -11.131 -4.280  -5.943  1.00 21.82  ? 271 LEU B CG  1 
ATOM   4471  C  CD1 . LEU B 1 271 ? -10.907 -3.341  -7.136  1.00 18.31  ? 271 LEU B CD1 1 
ATOM   4472  C  CD2 . LEU B 1 271 ? -11.696 -3.538  -4.717  1.00 17.46  ? 271 LEU B CD2 1 
ATOM   4473  N  N   . LEU B 1 272 ? -13.551 -8.137  -6.680  1.00 18.55  ? 272 LEU B N   1 
ATOM   4474  C  CA  . LEU B 1 272 ? -14.748 -8.894  -7.018  1.00 23.74  ? 272 LEU B CA  1 
ATOM   4475  C  C   . LEU B 1 272 ? -15.182 -9.805  -5.868  1.00 24.98  ? 272 LEU B C   1 
ATOM   4476  O  O   . LEU B 1 272 ? -16.381 -9.978  -5.628  1.00 27.37  ? 272 LEU B O   1 
ATOM   4477  C  CB  . LEU B 1 272 ? -14.511 -9.708  -8.294  1.00 27.89  ? 272 LEU B CB  1 
ATOM   4478  C  CG  . LEU B 1 272 ? -14.585 -8.861  -9.567  1.00 27.58  ? 272 LEU B CG  1 
ATOM   4479  C  CD1 . LEU B 1 272 ? -14.185 -9.655  -10.780 1.00 21.46  ? 272 LEU B CD1 1 
ATOM   4480  C  CD2 . LEU B 1 272 ? -15.973 -8.228  -9.734  1.00 26.61  ? 272 LEU B CD2 1 
ATOM   4481  N  N   . GLN B 1 273 ? -14.223 -10.417 -5.167  1.00 30.16  ? 273 GLN B N   1 
ATOM   4482  C  CA  . GLN B 1 273 ? -14.557 -11.402 -4.139  1.00 33.76  ? 273 GLN B CA  1 
ATOM   4483  C  C   . GLN B 1 273 ? -14.903 -10.767 -2.799  1.00 33.36  ? 273 GLN B C   1 
ATOM   4484  O  O   . GLN B 1 273 ? -15.758 -11.296 -2.082  1.00 30.36  ? 273 GLN B O   1 
ATOM   4485  C  CB  . GLN B 1 273 ? -13.426 -12.415 -3.973  1.00 25.63  ? 273 GLN B CB  1 
ATOM   4486  C  CG  . GLN B 1 273 ? -13.424 -13.446 -5.083  1.00 35.96  ? 273 GLN B CG  1 
ATOM   4487  C  CD  . GLN B 1 273 ? -12.248 -14.422 -5.011  1.00 38.53  ? 273 GLN B CD  1 
ATOM   4488  O  OE1 . GLN B 1 273 ? -11.142 -14.066 -4.593  1.00 39.89  ? 273 GLN B OE1 1 
ATOM   4489  N  NE2 . GLN B 1 273 ? -12.512 -15.679 -5.352  1.00 36.73  ? 273 GLN B NE2 1 
ATOM   4490  N  N   . ASN B 1 274 ? -14.310 -9.623  -2.466  1.00 35.41  ? 274 ASN B N   1 
ATOM   4491  C  CA  . ASN B 1 274 ? -14.514 -9.009  -1.160  1.00 30.48  ? 274 ASN B CA  1 
ATOM   4492  C  C   . ASN B 1 274 ? -15.367 -7.756  -1.214  1.00 25.46  ? 274 ASN B C   1 
ATOM   4493  O  O   . ASN B 1 274 ? -15.593 -7.133  -0.173  1.00 33.37  ? 274 ASN B O   1 
ATOM   4494  C  CB  . ASN B 1 274 ? -13.167 -8.658  -0.513  1.00 34.51  ? 274 ASN B CB  1 
ATOM   4495  C  CG  . ASN B 1 274 ? -12.181 -9.810  -0.557  1.00 44.27  ? 274 ASN B CG  1 
ATOM   4496  O  OD1 . ASN B 1 274 ? -11.023 -9.642  -0.949  1.00 45.43  ? 274 ASN B OD1 1 
ATOM   4497  N  ND2 . ASN B 1 274 ? -12.649 -10.998 -0.185  1.00 45.10  ? 274 ASN B ND2 1 
ATOM   4498  N  N   . GLY B 1 275 ? -15.868 -7.388  -2.377  1.00 27.20  ? 275 GLY B N   1 
ATOM   4499  C  CA  . GLY B 1 275 ? -16.629 -6.164  -2.486  1.00 31.48  ? 275 GLY B CA  1 
ATOM   4500  C  C   . GLY B 1 275 ? -15.751 -4.945  -2.222  1.00 32.95  ? 275 GLY B C   1 
ATOM   4501  O  O   . GLY B 1 275 ? -14.532 -5.018  -2.039  1.00 30.63  ? 275 GLY B O   1 
ATOM   4502  N  N   . MET B 1 276 ? -16.403 -3.807  -2.138  1.00 33.51  ? 276 MET B N   1 
ATOM   4503  C  CA  . MET B 1 276 ? -15.635 -2.589  -1.977  1.00 36.57  ? 276 MET B CA  1 
ATOM   4504  C  C   . MET B 1 276 ? -15.690 -2.056  -0.571  1.00 35.02  ? 276 MET B C   1 
ATOM   4505  O  O   . MET B 1 276 ? -15.046 -1.043  -0.294  1.00 39.07  ? 276 MET B O   1 
ATOM   4506  C  CB  . MET B 1 276 ? -16.075 -1.532  -2.984  1.00 41.98  ? 276 MET B CB  1 
ATOM   4507  C  CG  . MET B 1 276 ? -15.564 -1.907  -4.355  1.00 36.70  ? 276 MET B CG  1 
ATOM   4508  S  SD  . MET B 1 276 ? -15.738 -0.610  -5.533  1.00 50.55  ? 276 MET B SD  1 
ATOM   4509  C  CE  . MET B 1 276 ? -14.841 0.685   -4.682  1.00 37.19  ? 276 MET B CE  1 
ATOM   4510  N  N   . ASN B 1 277 ? -16.429 -2.727  0.316   1.00 31.69  ? 277 ASN B N   1 
ATOM   4511  C  CA  . ASN B 1 277 ? -16.412 -2.435  1.748   1.00 38.04  ? 277 ASN B CA  1 
ATOM   4512  C  C   . ASN B 1 277 ? -16.760 -0.973  1.997   1.00 32.84  ? 277 ASN B C   1 
ATOM   4513  O  O   . ASN B 1 277 ? -16.120 -0.289  2.799   1.00 28.73  ? 277 ASN B O   1 
ATOM   4514  C  CB  . ASN B 1 277 ? -15.059 -2.785  2.375   1.00 37.61  ? 277 ASN B CB  1 
ATOM   4515  C  CG  . ASN B 1 277 ? -14.800 -4.291  2.434   1.00 38.38  ? 277 ASN B CG  1 
ATOM   4516  O  OD1 . ASN B 1 277 ? -13.702 -4.760  2.119   1.00 37.28  ? 277 ASN B OD1 1 
ATOM   4517  N  ND2 . ASN B 1 277 ? -15.808 -5.047  2.848   1.00 36.19  ? 277 ASN B ND2 1 
ATOM   4518  N  N   . GLY B 1 278 ? -17.772 -0.496  1.280   1.00 31.57  ? 278 GLY B N   1 
ATOM   4519  C  CA  . GLY B 1 278 ? -18.236 0.867   1.391   1.00 31.93  ? 278 GLY B CA  1 
ATOM   4520  C  C   . GLY B 1 278 ? -17.278 1.929   0.904   1.00 29.78  ? 278 GLY B C   1 
ATOM   4521  O  O   . GLY B 1 278 ? -17.572 3.113   1.077   1.00 26.60  ? 278 GLY B O   1 
ATOM   4522  N  N   . ARG B 1 279 ? -16.144 1.545   0.317   1.00 30.30  ? 279 ARG B N   1 
ATOM   4523  C  CA  . ARG B 1 279 ? -15.144 2.463   -0.212  1.00 31.16  ? 279 ARG B CA  1 
ATOM   4524  C  C   . ARG B 1 279 ? -15.478 2.855   -1.645  1.00 30.07  ? 279 ARG B C   1 
ATOM   4525  O  O   . ARG B 1 279 ? -16.429 2.346   -2.241  1.00 32.20  ? 279 ARG B O   1 
ATOM   4526  C  CB  . ARG B 1 279 ? -13.757 1.827   -0.134  1.00 32.92  ? 279 ARG B CB  1 
ATOM   4527  C  CG  . ARG B 1 279 ? -12.981 2.213   1.108   1.00 36.52  ? 279 ARG B CG  1 
ATOM   4528  C  CD  . ARG B 1 279 ? -11.821 1.269   1.365   1.00 37.26  ? 279 ARG B CD  1 
ATOM   4529  N  NE  . ARG B 1 279 ? -12.297 -0.094  1.555   1.00 42.32  ? 279 ARG B NE  1 
ATOM   4530  C  CZ  . ARG B 1 279 ? -11.512 -1.159  1.650   1.00 43.26  ? 279 ARG B CZ  1 
ATOM   4531  N  NH1 . ARG B 1 279 ? -10.200 -1.051  1.597   1.00 45.66  ? 279 ARG B NH1 1 
ATOM   4532  N  NH2 . ARG B 1 279 ? -12.059 -2.362  1.791   1.00 42.07  ? 279 ARG B NH2 1 
ATOM   4533  N  N   . THR B 1 280 ? -14.712 3.809   -2.190  1.00 25.91  ? 280 THR B N   1 
ATOM   4534  C  CA  . THR B 1 280 ? -14.885 4.208   -3.585  1.00 28.21  ? 280 THR B CA  1 
ATOM   4535  C  C   . THR B 1 280 ? -13.546 4.269   -4.305  1.00 27.51  ? 280 THR B C   1 
ATOM   4536  O  O   . THR B 1 280 ? -12.479 4.269   -3.687  1.00 25.28  ? 280 THR B O   1 
ATOM   4537  C  CB  . THR B 1 280 ? -15.597 5.566   -3.746  1.00 30.06  ? 280 THR B CB  1 
ATOM   4538  O  OG1 . THR B 1 280 ? -14.733 6.619   -3.311  1.00 30.37  ? 280 THR B OG1 1 
ATOM   4539  C  CG2 . THR B 1 280 ? -16.923 5.595   -2.963  1.00 26.51  ? 280 THR B CG2 1 
ATOM   4540  N  N   . ILE B 1 281 ? -13.638 4.264   -5.640  1.00 27.76  ? 281 ILE B N   1 
ATOM   4541  C  CA  . ILE B 1 281 ? -12.505 4.368   -6.558  1.00 25.85  ? 281 ILE B CA  1 
ATOM   4542  C  C   . ILE B 1 281 ? -12.880 5.378   -7.636  1.00 25.06  ? 281 ILE B C   1 
ATOM   4543  O  O   . ILE B 1 281 ? -13.817 5.143   -8.414  1.00 22.91  ? 281 ILE B O   1 
ATOM   4544  C  CB  . ILE B 1 281 ? -12.140 3.011   -7.201  1.00 28.10  ? 281 ILE B CB  1 
ATOM   4545  C  CG1 . ILE B 1 281 ? -11.744 1.951   -6.158  1.00 22.66  ? 281 ILE B CG1 1 
ATOM   4546  C  CG2 . ILE B 1 281 ? -11.025 3.171   -8.250  1.00 23.70  ? 281 ILE B CG2 1 
ATOM   4547  C  CD1 . ILE B 1 281 ? -11.426 0.557   -6.788  1.00 19.33  ? 281 ILE B CD1 1 
ATOM   4548  N  N   . LEU B 1 282 ? -12.143 6.485   -7.707  1.00 27.94  ? 282 LEU B N   1 
ATOM   4549  C  CA  . LEU B 1 282 ? -12.496 7.552   -8.640  1.00 26.50  ? 282 LEU B CA  1 
ATOM   4550  C  C   . LEU B 1 282 ? -13.954 7.981   -8.453  1.00 23.58  ? 282 LEU B C   1 
ATOM   4551  O  O   . LEU B 1 282 ? -14.715 8.141   -9.412  1.00 21.28  ? 282 LEU B O   1 
ATOM   4552  C  CB  . LEU B 1 282 ? -12.221 7.115   -10.078 1.00 23.49  ? 282 LEU B CB  1 
ATOM   4553  C  CG  . LEU B 1 282 ? -10.743 6.927   -10.400 1.00 21.52  ? 282 LEU B CG  1 
ATOM   4554  C  CD1 . LEU B 1 282 ? -10.596 6.281   -11.759 1.00 15.54  ? 282 LEU B CD1 1 
ATOM   4555  C  CD2 . LEU B 1 282 ? -10.027 8.308   -10.339 1.00 20.79  ? 282 LEU B CD2 1 
ATOM   4556  N  N   . GLY B 1 283 ? -14.348 8.135   -7.189  1.00 25.95  ? 283 GLY B N   1 
ATOM   4557  C  CA  . GLY B 1 283 ? -15.656 8.656   -6.842  1.00 28.22  ? 283 GLY B CA  1 
ATOM   4558  C  C   . GLY B 1 283 ? -16.807 7.744   -7.185  1.00 31.67  ? 283 GLY B C   1 
ATOM   4559  O  O   . GLY B 1 283 ? -17.951 8.207   -7.285  1.00 37.67  ? 283 GLY B O   1 
ATOM   4560  N  N   . SER B 1 284 ? -16.545 6.454   -7.372  1.00 30.08  ? 284 SER B N   1 
ATOM   4561  C  CA  . SER B 1 284 ? -17.583 5.523   -7.776  1.00 27.38  ? 284 SER B CA  1 
ATOM   4562  C  C   . SER B 1 284 ? -17.602 4.362   -6.788  1.00 28.40  ? 284 SER B C   1 
ATOM   4563  O  O   . SER B 1 284 ? -16.549 3.895   -6.342  1.00 23.12  ? 284 SER B O   1 
ATOM   4564  C  CB  . SER B 1 284 ? -17.341 5.065   -9.209  1.00 23.28  ? 284 SER B CB  1 
ATOM   4565  O  OG  . SER B 1 284 ? -18.367 4.203   -9.637  1.00 33.28  ? 284 SER B OG  1 
ATOM   4566  N  N   . ALA B 1 285 ? -18.803 3.918   -6.427  1.00 27.07  ? 285 ALA B N   1 
ATOM   4567  C  CA  . ALA B 1 285 ? -18.967 2.818   -5.491  1.00 30.98  ? 285 ALA B CA  1 
ATOM   4568  C  C   . ALA B 1 285 ? -19.064 1.479   -6.190  1.00 28.81  ? 285 ALA B C   1 
ATOM   4569  O  O   . ALA B 1 285 ? -19.121 0.446   -5.518  1.00 33.45  ? 285 ALA B O   1 
ATOM   4570  C  CB  . ALA B 1 285 ? -20.217 3.030   -4.627  1.00 27.01  ? 285 ALA B CB  1 
ATOM   4571  N  N   . LEU B 1 286 ? -19.064 1.461   -7.513  1.00 28.78  ? 286 LEU B N   1 
ATOM   4572  C  CA  . LEU B 1 286 ? -18.989 0.207   -8.239  1.00 31.85  ? 286 LEU B CA  1 
ATOM   4573  C  C   . LEU B 1 286 ? -17.859 0.298   -9.254  1.00 32.58  ? 286 LEU B C   1 
ATOM   4574  O  O   . LEU B 1 286 ? -17.281 1.365   -9.484  1.00 29.66  ? 286 LEU B O   1 
ATOM   4575  C  CB  . LEU B 1 286 ? -20.317 -0.145  -8.930  1.00 29.69  ? 286 LEU B CB  1 
ATOM   4576  C  CG  . LEU B 1 286 ? -21.107 0.927   -9.683  1.00 35.59  ? 286 LEU B CG  1 
ATOM   4577  C  CD1 . LEU B 1 286 ? -20.453 1.299   -11.023 1.00 32.37  ? 286 LEU B CD1 1 
ATOM   4578  C  CD2 . LEU B 1 286 ? -22.545 0.458   -9.888  1.00 31.20  ? 286 LEU B CD2 1 
ATOM   4579  N  N   . LEU B 1 287 ? -17.570 -0.852  -9.863  1.00 31.73  ? 287 LEU B N   1 
ATOM   4580  C  CA  . LEU B 1 287 ? -16.493 -1.001  -10.827 1.00 25.56  ? 287 LEU B CA  1 
ATOM   4581  C  C   . LEU B 1 287 ? -17.013 -0.577  -12.194 1.00 27.36  ? 287 LEU B C   1 
ATOM   4582  O  O   . LEU B 1 287 ? -17.992 -1.140  -12.694 1.00 22.85  ? 287 LEU B O   1 
ATOM   4583  C  CB  . LEU B 1 287 ? -15.994 -2.446  -10.845 1.00 20.86  ? 287 LEU B CB  1 
ATOM   4584  C  CG  . LEU B 1 287 ? -15.515 -3.008  -9.495  1.00 23.51  ? 287 LEU B CG  1 
ATOM   4585  C  CD1 . LEU B 1 287 ? -15.187 -4.468  -9.588  1.00 21.95  ? 287 LEU B CD1 1 
ATOM   4586  C  CD2 . LEU B 1 287 ? -14.302 -2.265  -8.938  1.00 27.86  ? 287 LEU B CD2 1 
ATOM   4587  N  N   . GLU B 1 288 ? -16.393 0.456   -12.759 1.00 24.01  ? 288 GLU B N   1 
ATOM   4588  C  CA  . GLU B 1 288 ? -16.794 1.044   -14.032 1.00 23.79  ? 288 GLU B CA  1 
ATOM   4589  C  C   . GLU B 1 288 ? -16.241 0.258   -15.227 1.00 22.29  ? 288 GLU B C   1 
ATOM   4590  O  O   . GLU B 1 288 ? -15.046 -0.041  -15.278 1.00 21.71  ? 288 GLU B O   1 
ATOM   4591  C  CB  . GLU B 1 288 ? -16.293 2.482   -14.062 1.00 22.27  ? 288 GLU B CB  1 
ATOM   4592  C  CG  . GLU B 1 288 ? -17.145 3.404   -13.248 1.00 25.49  ? 288 GLU B CG  1 
ATOM   4593  C  CD  . GLU B 1 288 ? -18.412 3.716   -13.986 1.00 31.35  ? 288 GLU B CD  1 
ATOM   4594  O  OE1 . GLU B 1 288 ? -18.408 3.548   -15.237 1.00 33.23  ? 288 GLU B OE1 1 
ATOM   4595  O  OE2 . GLU B 1 288 ? -19.408 4.080   -13.328 1.00 36.93  ? 288 GLU B OE2 1 
ATOM   4596  N  N   . ASP B 1 289 ? -17.093 -0.066  -16.205 1.00 21.29  ? 289 ASP B N   1 
ATOM   4597  C  CA  . ASP B 1 289 ? -16.631 -0.806  -17.378 1.00 23.32  ? 289 ASP B CA  1 
ATOM   4598  C  C   . ASP B 1 289 ? -16.886 -0.077  -18.695 1.00 27.89  ? 289 ASP B C   1 
ATOM   4599  O  O   . ASP B 1 289 ? -16.824 -0.697  -19.766 1.00 24.97  ? 289 ASP B O   1 
ATOM   4600  C  CB  . ASP B 1 289 ? -17.248 -2.212  -17.429 1.00 26.38  ? 289 ASP B CB  1 
ATOM   4601  C  CG  . ASP B 1 289 ? -18.740 -2.206  -17.795 1.00 30.37  ? 289 ASP B CG  1 
ATOM   4602  O  OD1 . ASP B 1 289 ? -19.411 -1.168  -17.572 1.00 27.49  ? 289 ASP B OD1 1 
ATOM   4603  O  OD2 . ASP B 1 289 ? -19.241 -3.240  -18.324 1.00 30.06  ? 289 ASP B OD2 1 
ATOM   4604  N  N   . GLU B 1 290 ? -17.127 1.232   -18.669 1.00 25.53  ? 290 GLU B N   1 
ATOM   4605  C  CA  . GLU B 1 290 ? -17.360 1.937   -19.924 1.00 23.55  ? 290 GLU B CA  1 
ATOM   4606  C  C   . GLU B 1 290 ? -16.259 2.944   -20.226 1.00 28.99  ? 290 GLU B C   1 
ATOM   4607  O  O   . GLU B 1 290 ? -16.513 3.968   -20.865 1.00 33.62  ? 290 GLU B O   1 
ATOM   4608  C  CB  . GLU B 1 290 ? -18.719 2.623   -19.925 1.00 26.20  ? 290 GLU B CB  1 
ATOM   4609  C  CG  . GLU B 1 290 ? -19.872 1.633   -19.957 1.00 30.64  ? 290 GLU B CG  1 
ATOM   4610  C  CD  . GLU B 1 290 ? -21.183 2.254   -20.392 1.00 34.31  ? 290 GLU B CD  1 
ATOM   4611  O  OE1 . GLU B 1 290 ? -21.243 3.497   -20.536 1.00 36.73  ? 290 GLU B OE1 1 
ATOM   4612  O  OE2 . GLU B 1 290 ? -22.160 1.491   -20.564 1.00 36.95  ? 290 GLU B OE2 1 
ATOM   4613  N  N   . PHE B 1 291 ? -15.033 2.659   -19.786 1.00 21.45  ? 291 PHE B N   1 
ATOM   4614  C  CA  . PHE B 1 291 ? -13.838 3.363   -20.241 1.00 23.49  ? 291 PHE B CA  1 
ATOM   4615  C  C   . PHE B 1 291 ? -12.942 2.347   -20.948 1.00 23.88  ? 291 PHE B C   1 
ATOM   4616  O  O   . PHE B 1 291 ? -12.430 1.421   -20.311 1.00 18.77  ? 291 PHE B O   1 
ATOM   4617  C  CB  . PHE B 1 291 ? -13.083 4.020   -19.075 1.00 22.44  ? 291 PHE B CB  1 
ATOM   4618  C  CG  . PHE B 1 291 ? -13.814 5.171   -18.405 1.00 23.70  ? 291 PHE B CG  1 
ATOM   4619  C  CD1 . PHE B 1 291 ? -13.747 6.468   -18.925 1.00 25.64  ? 291 PHE B CD1 1 
ATOM   4620  C  CD2 . PHE B 1 291 ? -14.542 4.963   -17.238 1.00 24.60  ? 291 PHE B CD2 1 
ATOM   4621  C  CE1 . PHE B 1 291 ? -14.406 7.545   -18.304 1.00 25.61  ? 291 PHE B CE1 1 
ATOM   4622  C  CE2 . PHE B 1 291 ? -15.208 6.021   -16.607 1.00 28.21  ? 291 PHE B CE2 1 
ATOM   4623  C  CZ  . PHE B 1 291 ? -15.137 7.325   -17.147 1.00 27.63  ? 291 PHE B CZ  1 
ATOM   4624  N  N   . THR B 1 292 ? -12.737 2.532   -22.255 1.00 23.92  ? 292 THR B N   1 
ATOM   4625  C  CA  . THR B 1 292 ? -11.794 1.698   -22.980 1.00 20.77  ? 292 THR B CA  1 
ATOM   4626  C  C   . THR B 1 292 ? -10.372 2.025   -22.543 1.00 22.84  ? 292 THR B C   1 
ATOM   4627  O  O   . THR B 1 292 ? -10.122 3.066   -21.917 1.00 22.72  ? 292 THR B O   1 
ATOM   4628  C  CB  . THR B 1 292 ? -11.895 1.903   -24.498 1.00 25.73  ? 292 THR B CB  1 
ATOM   4629  O  OG1 . THR B 1 292 ? -11.394 3.204   -24.860 1.00 25.35  ? 292 THR B OG1 1 
ATOM   4630  C  CG2 . THR B 1 292 ? -13.310 1.687   -25.023 1.00 24.34  ? 292 THR B CG2 1 
ATOM   4631  N  N   . PRO B 1 293 ? -9.416  1.144   -22.859 1.00 19.93  ? 293 PRO B N   1 
ATOM   4632  C  CA  . PRO B 1 293 ? -8.018  1.490   -22.603 1.00 23.02  ? 293 PRO B CA  1 
ATOM   4633  C  C   . PRO B 1 293 ? -7.593  2.708   -23.377 1.00 23.41  ? 293 PRO B C   1 
ATOM   4634  O  O   . PRO B 1 293 ? -6.796  3.498   -22.864 1.00 21.83  ? 293 PRO B O   1 
ATOM   4635  C  CB  . PRO B 1 293 ? -7.255  0.232   -23.029 1.00 25.33  ? 293 PRO B CB  1 
ATOM   4636  C  CG  . PRO B 1 293 ? -8.251  -0.869  -22.893 1.00 23.58  ? 293 PRO B CG  1 
ATOM   4637  C  CD  . PRO B 1 293 ? -9.559  -0.250  -23.303 1.00 22.33  ? 293 PRO B CD  1 
ATOM   4638  N  N   . PHE B 1 294 ? -8.138  2.902   -24.587 1.00 28.89  ? 294 PHE B N   1 
ATOM   4639  C  CA  . PHE B 1 294 ? -7.870  4.129   -25.335 1.00 27.88  ? 294 PHE B CA  1 
ATOM   4640  C  C   . PHE B 1 294 ? -8.478  5.337   -24.638 1.00 26.75  ? 294 PHE B C   1 
ATOM   4641  O  O   . PHE B 1 294 ? -7.853  6.390   -24.574 1.00 28.08  ? 294 PHE B O   1 
ATOM   4642  C  CB  . PHE B 1 294 ? -8.402  4.005   -26.765 1.00 25.52  ? 294 PHE B CB  1 
ATOM   4643  C  CG  . PHE B 1 294 ? -8.340  5.291   -27.567 1.00 42.47  ? 294 PHE B CG  1 
ATOM   4644  C  CD1 . PHE B 1 294 ? -9.341  6.262   -27.456 1.00 47.83  ? 294 PHE B CD1 1 
ATOM   4645  C  CD2 . PHE B 1 294 ? -7.301  5.518   -28.462 1.00 43.65  ? 294 PHE B CD2 1 
ATOM   4646  C  CE1 . PHE B 1 294 ? -9.282  7.437   -28.199 1.00 43.83  ? 294 PHE B CE1 1 
ATOM   4647  C  CE2 . PHE B 1 294 ? -7.246  6.680   -29.207 1.00 34.07  ? 294 PHE B CE2 1 
ATOM   4648  C  CZ  . PHE B 1 294 ? -8.234  7.638   -29.075 1.00 41.77  ? 294 PHE B CZ  1 
ATOM   4649  N  N   . ASP B 1 295 ? -9.699  5.208   -24.112 1.00 30.95  ? 295 ASP B N   1 
ATOM   4650  C  CA  . ASP B 1 295 ? -10.317 6.321   -23.392 1.00 30.75  ? 295 ASP B CA  1 
ATOM   4651  C  C   . ASP B 1 295 ? -9.407  6.829   -22.280 1.00 29.17  ? 295 ASP B C   1 
ATOM   4652  O  O   . ASP B 1 295 ? -9.192  8.038   -22.136 1.00 29.17  ? 295 ASP B O   1 
ATOM   4653  C  CB  . ASP B 1 295 ? -11.671 5.890   -22.800 1.00 29.29  ? 295 ASP B CB  1 
ATOM   4654  C  CG  . ASP B 1 295 ? -12.690 5.538   -23.864 1.00 32.19  ? 295 ASP B CG  1 
ATOM   4655  O  OD1 . ASP B 1 295 ? -12.405 5.858   -25.041 1.00 34.53  ? 295 ASP B OD1 1 
ATOM   4656  O  OD2 . ASP B 1 295 ? -13.752 4.943   -23.538 1.00 26.56  ? 295 ASP B OD2 1 
ATOM   4657  N  N   . VAL B 1 296 ? -8.861  5.899   -21.492 1.00 29.10  ? 296 VAL B N   1 
ATOM   4658  C  CA  . VAL B 1 296 ? -8.014  6.243   -20.358 1.00 24.09  ? 296 VAL B CA  1 
ATOM   4659  C  C   . VAL B 1 296 ? -6.791  7.003   -20.828 1.00 29.54  ? 296 VAL B C   1 
ATOM   4660  O  O   . VAL B 1 296 ? -6.468  8.077   -20.305 1.00 33.22  ? 296 VAL B O   1 
ATOM   4661  C  CB  . VAL B 1 296 ? -7.610  4.974   -19.585 1.00 21.81  ? 296 VAL B CB  1 
ATOM   4662  C  CG1 . VAL B 1 296 ? -6.621  5.325   -18.470 1.00 22.34  ? 296 VAL B CG1 1 
ATOM   4663  C  CG2 . VAL B 1 296 ? -8.835  4.250   -19.038 1.00 20.70  ? 296 VAL B CG2 1 
ATOM   4664  N  N   . VAL B 1 297 ? -6.056  6.423   -21.779 1.00 27.22  ? 297 VAL B N   1 
ATOM   4665  C  CA  . VAL B 1 297 ? -4.859  7.072   -22.307 1.00 28.33  ? 297 VAL B CA  1 
ATOM   4666  C  C   . VAL B 1 297 ? -5.202  8.466   -22.847 1.00 31.81  ? 297 VAL B C   1 
ATOM   4667  O  O   . VAL B 1 297 ? -4.502  9.444   -22.571 1.00 34.43  ? 297 VAL B O   1 
ATOM   4668  C  CB  . VAL B 1 297 ? -4.199  6.171   -23.368 1.00 27.69  ? 297 VAL B CB  1 
ATOM   4669  C  CG1 . VAL B 1 297 ? -3.066  6.896   -24.065 1.00 27.72  ? 297 VAL B CG1 1 
ATOM   4670  C  CG2 . VAL B 1 297 ? -3.702  4.865   -22.727 1.00 28.82  ? 297 VAL B CG2 1 
ATOM   4671  N  N   . ARG B 1 298 ? -6.286  8.573   -23.624 1.00 27.18  ? 298 ARG B N   1 
ATOM   4672  C  CA  . ARG B 1 298 ? -6.707  9.863   -24.167 1.00 31.90  ? 298 ARG B CA  1 
ATOM   4673  C  C   . ARG B 1 298 ? -6.922  10.886  -23.053 1.00 35.54  ? 298 ARG B C   1 
ATOM   4674  O  O   . ARG B 1 298 ? -6.360  11.988  -23.081 1.00 36.78  ? 298 ARG B O   1 
ATOM   4675  C  CB  . ARG B 1 298 ? -7.987  9.679   -25.000 1.00 31.89  ? 298 ARG B CB  1 
ATOM   4676  C  CG  . ARG B 1 298 ? -8.681  10.981  -25.472 1.00 41.45  ? 298 ARG B CG  1 
ATOM   4677  C  CD  . ARG B 1 298 ? -9.903  10.717  -26.381 1.00 46.00  ? 298 ARG B CD  1 
ATOM   4678  N  NE  . ARG B 1 298 ? -11.103 10.156  -25.743 1.00 49.03  ? 298 ARG B NE  1 
ATOM   4679  C  CZ  . ARG B 1 298 ? -12.170 10.853  -25.354 1.00 46.91  ? 298 ARG B CZ  1 
ATOM   4680  N  NH1 . ARG B 1 298 ? -12.240 12.167  -25.509 1.00 44.25  ? 298 ARG B NH1 1 
ATOM   4681  N  NH2 . ARG B 1 298 ? -13.226 10.209  -24.863 1.00 38.43  ? 298 ARG B NH2 1 
ATOM   4682  N  N   . GLN B 1 299 ? -7.724  10.533  -22.048 1.00 33.25  ? 299 GLN B N   1 
ATOM   4683  C  CA  . GLN B 1 299 ? -8.014  11.482  -20.984 1.00 26.93  ? 299 GLN B CA  1 
ATOM   4684  C  C   . GLN B 1 299 ? -6.818  11.701  -20.069 1.00 30.11  ? 299 GLN B C   1 
ATOM   4685  O  O   . GLN B 1 299 ? -6.674  12.790  -19.509 1.00 34.27  ? 299 GLN B O   1 
ATOM   4686  C  CB  . GLN B 1 299 ? -9.242  11.042  -20.189 1.00 23.70  ? 299 GLN B CB  1 
ATOM   4687  C  CG  . GLN B 1 299 ? -9.618  12.043  -19.148 1.00 23.46  ? 299 GLN B CG  1 
ATOM   4688  C  CD  . GLN B 1 299 ? -10.873 11.732  -18.421 1.00 17.03  ? 299 GLN B CD  1 
ATOM   4689  O  OE1 . GLN B 1 299 ? -11.078 12.236  -17.338 1.00 20.60  ? 299 GLN B OE1 1 
ATOM   4690  N  NE2 . GLN B 1 299 ? -11.751 10.949  -19.026 1.00 20.76  ? 299 GLN B NE2 1 
ATOM   4691  N  N   . CYS B 1 300 ? -5.992  10.678  -19.835 1.00 31.28  ? 300 CYS B N   1 
ATOM   4692  C  CA  . CYS B 1 300 ? -4.869  10.874  -18.922 1.00 34.23  ? 300 CYS B CA  1 
ATOM   4693  C  C   . CYS B 1 300 ? -3.644  11.519  -19.576 1.00 35.77  ? 300 CYS B C   1 
ATOM   4694  O  O   . CYS B 1 300 ? -2.734  11.921  -18.844 1.00 33.64  ? 300 CYS B O   1 
ATOM   4695  C  CB  . CYS B 1 300 ? -4.457  9.550   -18.258 1.00 34.44  ? 300 CYS B CB  1 
ATOM   4696  S  SG  . CYS B 1 300 ? -5.602  8.908   -16.991 1.00 41.29  ? 300 CYS B SG  1 
ATOM   4697  N  N   . SER B 1 301 ? -3.596  11.658  -20.914 1.00 39.68  ? 301 SER B N   1 
ATOM   4698  C  CA  . SER B 1 301 ? -2.447  12.267  -21.582 1.00 43.47  ? 301 SER B CA  1 
ATOM   4699  C  C   . SER B 1 301 ? -2.707  13.618  -22.240 1.00 44.97  ? 301 SER B C   1 
ATOM   4700  O  O   . SER B 1 301 ? -1.741  14.339  -22.504 1.00 49.82  ? 301 SER B O   1 
ATOM   4701  C  CB  . SER B 1 301 ? -1.892  11.332  -22.665 1.00 46.58  ? 301 SER B CB  1 
ATOM   4702  O  OG  . SER B 1 301 ? -2.558  11.556  -23.898 1.00 49.99  ? 301 SER B OG  1 
ATOM   4703  N  N   . GLY B 1 302 ? -3.958  13.976  -22.528 1.00 56.49  ? 302 GLY B N   1 
ATOM   4704  C  CA  . GLY B 1 302 ? -4.302  15.289  -23.056 1.00 53.08  ? 302 GLY B CA  1 
ATOM   4705  C  C   . GLY B 1 302 ? -4.466  15.452  -24.562 1.00 63.47  ? 302 GLY B C   1 
ATOM   4706  O  O   . GLY B 1 302 ? -4.190  16.544  -25.080 1.00 56.08  ? 302 GLY B O   1 
ATOM   4707  N  N   . VAL B 1 303 ? -4.907  14.410  -25.278 1.00 70.69  ? 303 VAL B N   1 
ATOM   4708  C  CA  . VAL B 1 303 ? -5.092  14.490  -26.728 1.00 84.53  ? 303 VAL B CA  1 
ATOM   4709  C  C   . VAL B 1 303 ? -6.251  15.426  -27.064 1.00 90.57  ? 303 VAL B C   1 
ATOM   4710  O  O   . VAL B 1 303 ? -7.309  15.394  -26.417 1.00 86.61  ? 303 VAL B O   1 
ATOM   4711  C  CB  . VAL B 1 303 ? -5.330  13.086  -27.317 1.00 75.63  ? 303 VAL B CB  1 
ATOM   4712  C  CG1 . VAL B 1 303 ? -5.859  13.176  -28.744 1.00 82.34  ? 303 VAL B CG1 1 
ATOM   4713  C  CG2 . VAL B 1 303 ? -4.054  12.257  -27.276 1.00 74.30  ? 303 VAL B CG2 1 
ATOM   4714  N  N   . THR B 1 304 ? -6.061  16.268  -28.080 1.00 84.72  ? 304 THR B N   1 
ATOM   4715  C  CA  . THR B 1 304 ? -7.059  17.239  -28.512 1.00 81.63  ? 304 THR B CA  1 
ATOM   4716  C  C   . THR B 1 304 ? -7.501  16.984  -29.949 1.00 90.69  ? 304 THR B C   1 
ATOM   4717  O  O   . THR B 1 304 ? -6.984  16.103  -30.643 1.00 90.82  ? 304 THR B O   1 
ATOM   4718  C  CB  . THR B 1 304 ? -6.532  18.667  -28.372 1.00 80.94  ? 304 THR B CB  1 
ATOM   4719  O  OG1 . THR B 1 304 ? -5.329  18.813  -29.140 1.00 82.22  ? 304 THR B OG1 1 
ATOM   4720  C  CG2 . THR B 1 304 ? -6.255  18.959  -26.936 1.00 83.39  ? 304 THR B CG2 1 
ATOM   4721  N  N   . PHE B 1 305 ? -8.492  17.768  -30.380 1.00 87.73  ? 305 PHE B N   1 
ATOM   4722  C  CA  . PHE B 1 305 ? -9.067  17.648  -31.720 1.00 90.59  ? 305 PHE B CA  1 
ATOM   4723  C  C   . PHE B 1 305 ? -9.344  19.013  -32.351 1.00 89.60  ? 305 PHE B C   1 
ATOM   4724  O  O   . PHE B 1 305 ? -9.716  19.103  -33.523 1.00 92.63  ? 305 PHE B O   1 
ATOM   4725  C  CB  . PHE B 1 305 ? -10.353 16.819  -31.659 1.00 87.35  ? 305 PHE B CB  1 
ATOM   4726  C  CG  . PHE B 1 305 ? -10.206 15.558  -30.861 1.00 86.77  ? 305 PHE B CG  1 
ATOM   4727  C  CD1 . PHE B 1 305 ? -9.561  14.453  -31.399 1.00 83.13  ? 305 PHE B CD1 1 
ATOM   4728  C  CD2 . PHE B 1 305 ? -10.681 15.489  -29.560 1.00 86.29  ? 305 PHE B CD2 1 
ATOM   4729  C  CE1 . PHE B 1 305 ? -9.408  13.302  -30.663 1.00 80.41  ? 305 PHE B CE1 1 
ATOM   4730  C  CE2 . PHE B 1 305 ? -10.530 14.339  -28.818 1.00 84.84  ? 305 PHE B CE2 1 
ATOM   4731  C  CZ  . PHE B 1 305 ? -9.891  13.244  -29.370 1.00 84.75  ? 305 PHE B CZ  1 
ATOM   4732  N  N   . SER C 1 1   ? -35.975 38.468  -63.560 1.00 29.08  ? 1   SER D N   1 
ATOM   4733  C  CA  . SER C 1 1   ? -35.478 38.737  -62.220 1.00 27.87  ? 1   SER D CA  1 
ATOM   4734  C  C   . SER C 1 1   ? -33.956 38.745  -62.194 1.00 26.18  ? 1   SER D C   1 
ATOM   4735  O  O   . SER C 1 1   ? -33.304 38.905  -63.216 1.00 28.02  ? 1   SER D O   1 
ATOM   4736  C  CB  . SER C 1 1   ? -36.007 37.691  -61.238 1.00 33.54  ? 1   SER D CB  1 
ATOM   4737  O  OG  . SER C 1 1   ? -35.660 36.389  -61.672 1.00 30.90  ? 1   SER D OG  1 
ATOM   4738  N  N   . GLY C 1 2   ? -33.387 38.660  -61.010 1.00 26.99  ? 2   GLY D N   1 
ATOM   4739  C  CA  . GLY C 1 2   ? -31.936 38.813  -60.900 1.00 28.73  ? 2   GLY D CA  1 
ATOM   4740  C  C   . GLY C 1 2   ? -31.562 40.148  -60.301 1.00 27.12  ? 2   GLY D C   1 
ATOM   4741  O  O   . GLY C 1 2   ? -32.296 41.117  -60.493 1.00 31.66  ? 2   GLY D O   1 
ATOM   4742  N  N   . PHE C 1 3   ? -30.466 40.164  -59.567 1.00 27.23  ? 3   PHE D N   1 
ATOM   4743  C  CA  . PHE C 1 3   ? -29.979 41.405  -58.933 1.00 27.47  ? 3   PHE D CA  1 
ATOM   4744  C  C   . PHE C 1 3   ? -28.455 41.420  -59.050 1.00 30.74  ? 3   PHE D C   1 
ATOM   4745  O  O   . PHE C 1 3   ? -27.794 40.543  -58.493 1.00 25.53  ? 3   PHE D O   1 
ATOM   4746  C  CB  . PHE C 1 3   ? -30.480 41.514  -57.499 1.00 25.13  ? 3   PHE D CB  1 
ATOM   4747  C  CG  . PHE C 1 3   ? -30.567 42.922  -56.981 1.00 27.25  ? 3   PHE D CG  1 
ATOM   4748  C  CD1 . PHE C 1 3   ? -31.582 43.766  -57.394 1.00 29.42  ? 3   PHE D CD1 1 
ATOM   4749  C  CD2 . PHE C 1 3   ? -29.630 43.400  -56.086 1.00 25.10  ? 3   PHE D CD2 1 
ATOM   4750  C  CE1 . PHE C 1 3   ? -31.659 45.064  -56.920 1.00 24.95  ? 3   PHE D CE1 1 
ATOM   4751  C  CE2 . PHE C 1 3   ? -29.719 44.692  -55.602 1.00 22.79  ? 3   PHE D CE2 1 
ATOM   4752  C  CZ  . PHE C 1 3   ? -30.723 45.525  -56.028 1.00 25.11  ? 3   PHE D CZ  1 
ATOM   4753  N  N   . ARG C 1 4   ? -27.937 42.401  -59.783 1.00 23.10  ? 4   ARG D N   1 
ATOM   4754  C  CA  . ARG C 1 4   ? -26.481 42.487  -59.993 1.00 28.52  ? 4   ARG D CA  1 
ATOM   4755  C  C   . ARG C 1 4   ? -25.936 43.852  -59.575 1.00 27.69  ? 4   ARG D C   1 
ATOM   4756  O  O   . ARG C 1 4   ? -26.682 44.819  -59.672 1.00 26.36  ? 4   ARG D O   1 
ATOM   4757  C  CB  . ARG C 1 4   ? -26.155 42.220  -61.468 1.00 27.03  ? 4   ARG D CB  1 
ATOM   4758  C  CG  . ARG C 1 4   ? -26.647 40.889  -62.012 1.00 29.80  ? 4   ARG D CG  1 
ATOM   4759  C  CD  . ARG C 1 4   ? -25.735 39.729  -61.684 1.00 32.48  ? 4   ARG D CD  1 
ATOM   4760  N  NE  . ARG C 1 4   ? -24.360 40.132  -61.453 1.00 29.40  ? 4   ARG D NE  1 
ATOM   4761  C  CZ  . ARG C 1 4   ? -23.295 39.397  -61.726 1.00 47.66  ? 4   ARG D CZ  1 
ATOM   4762  N  NH1 . ARG C 1 4   ? -23.426 38.196  -62.264 1.00 39.14  ? 4   ARG D NH1 1 
ATOM   4763  N  NH2 . ARG C 1 4   ? -22.093 39.870  -61.451 1.00 61.63  ? 4   ARG D NH2 1 
ATOM   4764  N  N   . LYS C 1 5   ? -24.684 43.903  -59.106 1.00 25.57  ? 5   LYS D N   1 
ATOM   4765  C  CA  . LYS C 1 5   ? -24.032 45.222  -58.867 1.00 31.77  ? 5   LYS D CA  1 
ATOM   4766  C  C   . LYS C 1 5   ? -24.013 45.873  -60.251 1.00 25.47  ? 5   LYS D C   1 
ATOM   4767  O  O   . LYS C 1 5   ? -23.263 45.417  -61.111 1.00 33.91  ? 5   LYS D O   1 
ATOM   4768  C  CB  . LYS C 1 5   ? -22.684 45.117  -58.155 1.00 26.02  ? 5   LYS D CB  1 
ATOM   4769  C  CG  . LYS C 1 5   ? -22.099 46.435  -57.671 1.00 36.97  ? 5   LYS D CG  1 
ATOM   4770  C  CD  . LYS C 1 5   ? -22.848 47.048  -56.504 1.00 34.57  ? 5   LYS D CD  1 
ATOM   4771  C  CE  . LYS C 1 5   ? -22.498 46.413  -55.176 1.00 31.79  ? 5   LYS D CE  1 
ATOM   4772  N  NZ  . LYS C 1 5   ? -21.226 46.939  -54.632 1.00 39.85  ? 5   LYS D NZ  1 
ATOM   4773  N  N   . MET C 1 6   ? -24.855 46.861  -60.447 1.00 25.75  ? 6   MET D N   1 
ATOM   4774  C  CA  . MET C 1 6   ? -25.080 47.440  -61.766 1.00 27.29  ? 6   MET D CA  1 
ATOM   4775  C  C   . MET C 1 6   ? -24.598 48.881  -61.764 1.00 26.71  ? 6   MET D C   1 
ATOM   4776  O  O   . MET C 1 6   ? -24.975 49.654  -60.877 1.00 26.59  ? 6   MET D O   1 
ATOM   4777  C  CB  . MET C 1 6   ? -26.566 47.388  -62.115 1.00 23.89  ? 6   MET D CB  1 
ATOM   4778  C  CG  . MET C 1 6   ? -26.904 47.459  -63.571 1.00 26.89  ? 6   MET D CG  1 
ATOM   4779  S  SD  . MET C 1 6   ? -28.709 47.417  -63.757 1.00 39.92  ? 6   MET D SD  1 
ATOM   4780  C  CE  . MET C 1 6   ? -28.994 45.714  -64.214 1.00 32.66  ? 6   MET D CE  1 
ATOM   4781  N  N   . ALA C 1 7   ? -23.775 49.239  -62.749 1.00 23.49  ? 7   ALA D N   1 
ATOM   4782  C  CA  . ALA C 1 7   ? -23.318 50.614  -62.933 1.00 24.88  ? 7   ALA D CA  1 
ATOM   4783  C  C   . ALA C 1 7   ? -24.158 51.339  -63.977 1.00 19.29  ? 7   ALA D C   1 
ATOM   4784  O  O   . ALA C 1 7   ? -24.702 50.731  -64.899 1.00 19.42  ? 7   ALA D O   1 
ATOM   4785  C  CB  . ALA C 1 7   ? -21.847 50.666  -63.348 1.00 21.74  ? 7   ALA D CB  1 
ATOM   4786  N  N   . PHE C 1 8   ? -24.226 52.660  -63.840 1.00 24.48  ? 8   PHE D N   1 
ATOM   4787  C  CA  . PHE C 1 8   ? -24.846 53.475  -64.870 1.00 26.85  ? 8   PHE D CA  1 
ATOM   4788  C  C   . PHE C 1 8   ? -24.086 53.300  -66.179 1.00 25.80  ? 8   PHE D C   1 
ATOM   4789  O  O   . PHE C 1 8   ? -22.860 53.145  -66.180 1.00 26.05  ? 8   PHE D O   1 
ATOM   4790  C  CB  . PHE C 1 8   ? -24.844 54.953  -64.469 1.00 24.10  ? 8   PHE D CB  1 
ATOM   4791  C  CG  . PHE C 1 8   ? -25.817 55.274  -63.372 1.00 30.00  ? 8   PHE D CG  1 
ATOM   4792  C  CD1 . PHE C 1 8   ? -27.171 55.418  -63.636 1.00 35.43  ? 8   PHE D CD1 1 
ATOM   4793  C  CD2 . PHE C 1 8   ? -25.386 55.393  -62.060 1.00 30.10  ? 8   PHE D CD2 1 
ATOM   4794  C  CE1 . PHE C 1 8   ? -28.078 55.695  -62.588 1.00 38.80  ? 8   PHE D CE1 1 
ATOM   4795  C  CE2 . PHE C 1 8   ? -26.288 55.672  -61.025 1.00 28.61  ? 8   PHE D CE2 1 
ATOM   4796  C  CZ  . PHE C 1 8   ? -27.627 55.817  -61.286 1.00 28.83  ? 8   PHE D CZ  1 
ATOM   4797  N  N   . PRO C 1 9   ? -24.787 53.318  -67.308 1.00 26.68  ? 9   PRO D N   1 
ATOM   4798  C  CA  . PRO C 1 9   ? -24.084 53.368  -68.598 1.00 25.91  ? 9   PRO D CA  1 
ATOM   4799  C  C   . PRO C 1 9   ? -23.162 54.583  -68.648 1.00 24.03  ? 9   PRO D C   1 
ATOM   4800  O  O   . PRO C 1 9   ? -23.487 55.652  -68.139 1.00 22.99  ? 9   PRO D O   1 
ATOM   4801  C  CB  . PRO C 1 9   ? -25.222 53.454  -69.624 1.00 27.02  ? 9   PRO D CB  1 
ATOM   4802  C  CG  . PRO C 1 9   ? -26.438 53.929  -68.829 1.00 29.67  ? 9   PRO D CG  1 
ATOM   4803  C  CD  . PRO C 1 9   ? -26.256 53.418  -67.444 1.00 27.58  ? 9   PRO D CD  1 
ATOM   4804  N  N   . SER C 1 10  ? -21.974 54.382  -69.208 1.00 21.43  ? 10  SER D N   1 
ATOM   4805  C  CA  . SER C 1 10  ? -20.891 55.339  -69.097 1.00 25.56  ? 10  SER D CA  1 
ATOM   4806  C  C   . SER C 1 10  ? -20.707 56.196  -70.352 1.00 26.88  ? 10  SER D C   1 
ATOM   4807  O  O   . SER C 1 10  ? -19.804 57.041  -70.372 1.00 22.41  ? 10  SER D O   1 
ATOM   4808  C  CB  . SER C 1 10  ? -19.581 54.610  -68.795 1.00 20.24  ? 10  SER D CB  1 
ATOM   4809  O  OG  . SER C 1 10  ? -19.235 53.764  -69.870 1.00 19.57  ? 10  SER D OG  1 
ATOM   4810  N  N   . GLY C 1 11  ? -21.556 56.024  -71.373 1.00 24.60  ? 11  GLY D N   1 
ATOM   4811  C  CA  . GLY C 1 11  ? -21.339 56.724  -72.632 1.00 25.55  ? 11  GLY D CA  1 
ATOM   4812  C  C   . GLY C 1 11  ? -21.259 58.232  -72.464 1.00 28.94  ? 11  GLY D C   1 
ATOM   4813  O  O   . GLY C 1 11  ? -20.284 58.865  -72.895 1.00 31.62  ? 11  GLY D O   1 
ATOM   4814  N  N   . LYS C 1 12  ? -22.253 58.822  -71.783 1.00 23.87  ? 12  LYS D N   1 
ATOM   4815  C  CA  . LYS C 1 12  ? -22.277 60.273  -71.614 1.00 27.22  ? 12  LYS D CA  1 
ATOM   4816  C  C   . LYS C 1 12  ? -20.991 60.795  -70.991 1.00 29.60  ? 12  LYS D C   1 
ATOM   4817  O  O   . LYS C 1 12  ? -20.546 61.908  -71.308 1.00 27.35  ? 12  LYS D O   1 
ATOM   4818  C  CB  . LYS C 1 12  ? -23.461 60.692  -70.743 1.00 27.54  ? 12  LYS D CB  1 
ATOM   4819  C  CG  . LYS C 1 12  ? -24.819 60.445  -71.338 1.00 32.62  ? 12  LYS D CG  1 
ATOM   4820  C  CD  . LYS C 1 12  ? -25.882 60.994  -70.407 1.00 44.39  ? 12  LYS D CD  1 
ATOM   4821  C  CE  . LYS C 1 12  ? -27.285 60.587  -70.837 1.00 49.31  ? 12  LYS D CE  1 
ATOM   4822  N  NZ  . LYS C 1 12  ? -27.627 61.159  -72.149 1.00 44.20  ? 12  LYS D NZ  1 
ATOM   4823  N  N   . VAL C 1 13  ? -20.371 60.005  -70.123 1.00 27.06  ? 13  VAL D N   1 
ATOM   4824  C  CA  . VAL C 1 13  ? -19.173 60.459  -69.432 1.00 24.20  ? 13  VAL D CA  1 
ATOM   4825  C  C   . VAL C 1 13  ? -17.914 60.198  -70.256 1.00 26.71  ? 13  VAL D C   1 
ATOM   4826  O  O   . VAL C 1 13  ? -16.979 61.011  -70.214 1.00 21.05  ? 13  VAL D O   1 
ATOM   4827  C  CB  . VAL C 1 13  ? -19.109 59.802  -68.048 1.00 21.90  ? 13  VAL D CB  1 
ATOM   4828  C  CG1 . VAL C 1 13  ? -17.885 60.277  -67.282 1.00 25.48  ? 13  VAL D CG1 1 
ATOM   4829  C  CG2 . VAL C 1 13  ? -20.383 60.121  -67.292 1.00 18.79  ? 13  VAL D CG2 1 
ATOM   4830  N  N   . GLU C 1 14  ? -17.897 59.104  -71.040 1.00 21.20  ? 14  GLU D N   1 
ATOM   4831  C  CA  . GLU C 1 14  ? -16.751 58.802  -71.903 1.00 22.96  ? 14  GLU D CA  1 
ATOM   4832  C  C   . GLU C 1 14  ? -16.416 59.989  -72.826 1.00 22.25  ? 14  GLU D C   1 
ATOM   4833  O  O   . GLU C 1 14  ? -15.242 60.313  -73.037 1.00 24.63  ? 14  GLU D O   1 
ATOM   4834  C  CB  . GLU C 1 14  ? -17.040 57.527  -72.730 1.00 20.13  ? 14  GLU D CB  1 
ATOM   4835  C  CG  . GLU C 1 14  ? -17.231 56.226  -71.911 1.00 25.75  ? 14  GLU D CG  1 
ATOM   4836  C  CD  . GLU C 1 14  ? -17.762 55.017  -72.727 1.00 25.63  ? 14  GLU D CD  1 
ATOM   4837  O  OE1 . GLU C 1 14  ? -17.235 54.697  -73.806 1.00 25.90  ? 14  GLU D OE1 1 
ATOM   4838  O  OE2 . GLU C 1 14  ? -18.717 54.363  -72.273 1.00 28.11  ? 14  GLU D OE2 1 
ATOM   4839  N  N   . GLY C 1 15  ? -17.439 60.633  -73.399 1.00 25.07  ? 15  GLY D N   1 
ATOM   4840  C  CA  . GLY C 1 15  ? -17.297 61.791  -74.263 1.00 22.69  ? 15  GLY D CA  1 
ATOM   4841  C  C   . GLY C 1 15  ? -16.777 63.041  -73.583 1.00 24.98  ? 15  GLY D C   1 
ATOM   4842  O  O   . GLY C 1 15  ? -16.586 64.065  -74.251 1.00 26.49  ? 15  GLY D O   1 
ATOM   4843  N  N   . CYS C 1 16  ? -16.588 63.005  -72.265 1.00 25.54  ? 16  CYS D N   1 
ATOM   4844  C  CA  . CYS C 1 16  ? -16.059 64.144  -71.530 1.00 21.04  ? 16  CYS D CA  1 
ATOM   4845  C  C   . CYS C 1 16  ? -14.628 63.933  -71.067 1.00 22.11  ? 16  CYS D C   1 
ATOM   4846  O  O   . CYS C 1 16  ? -14.016 64.869  -70.545 1.00 25.25  ? 16  CYS D O   1 
ATOM   4847  C  CB  . CYS C 1 16  ? -16.948 64.453  -70.324 1.00 21.83  ? 16  CYS D CB  1 
ATOM   4848  S  SG  . CYS C 1 16  ? -18.634 64.802  -70.780 1.00 24.75  ? 16  CYS D SG  1 
ATOM   4849  N  N   . MET C 1 17  ? -14.058 62.760  -71.278 1.00 18.53  ? 17  MET D N   1 
ATOM   4850  C  CA  . MET C 1 17  ? -12.755 62.465  -70.708 1.00 23.88  ? 17  MET D CA  1 
ATOM   4851  C  C   . MET C 1 17  ? -11.631 62.967  -71.617 1.00 22.13  ? 17  MET D C   1 
ATOM   4852  O  O   . MET C 1 17  ? -11.665 62.762  -72.838 1.00 23.11  ? 17  MET D O   1 
ATOM   4853  C  CB  . MET C 1 17  ? -12.624 60.958  -70.445 1.00 21.58  ? 17  MET D CB  1 
ATOM   4854  C  CG  . MET C 1 17  ? -13.644 60.409  -69.436 1.00 15.67  ? 17  MET D CG  1 
ATOM   4855  S  SD  . MET C 1 17  ? -13.722 61.374  -67.898 1.00 21.70  ? 17  MET D SD  1 
ATOM   4856  C  CE  . MET C 1 17  ? -12.016 61.343  -67.346 1.00 22.75  ? 17  MET D CE  1 
ATOM   4857  N  N   . VAL C 1 18  ? -10.650 63.655  -71.020 1.00 22.59  ? 18  VAL D N   1 
ATOM   4858  C  CA  . VAL C 1 18  ? -9.474  64.129  -71.740 1.00 21.13  ? 18  VAL D CA  1 
ATOM   4859  C  C   . VAL C 1 18  ? -8.229  63.771  -70.941 1.00 22.70  ? 18  VAL D C   1 
ATOM   4860  O  O   . VAL C 1 18  ? -8.297  63.296  -69.810 1.00 21.51  ? 18  VAL D O   1 
ATOM   4861  C  CB  . VAL C 1 18  ? -9.497  65.654  -72.014 1.00 20.64  ? 18  VAL D CB  1 
ATOM   4862  C  CG1 . VAL C 1 18  ? -10.731 66.059  -72.847 1.00 18.39  ? 18  VAL D CG1 1 
ATOM   4863  C  CG2 . VAL C 1 18  ? -9.392  66.446  -70.715 1.00 17.77  ? 18  VAL D CG2 1 
ATOM   4864  N  N   . GLN C 1 19  ? -7.083  64.029  -71.552 1.00 26.17  ? 19  GLN D N   1 
ATOM   4865  C  CA  . GLN C 1 19  ? -5.781  63.779  -70.962 1.00 23.99  ? 19  GLN D CA  1 
ATOM   4866  C  C   . GLN C 1 19  ? -5.073  65.101  -70.723 1.00 23.33  ? 19  GLN D C   1 
ATOM   4867  O  O   . GLN C 1 19  ? -4.897  65.892  -71.653 1.00 27.81  ? 19  GLN D O   1 
ATOM   4868  C  CB  . GLN C 1 19  ? -4.950  62.895  -71.882 1.00 24.10  ? 19  GLN D CB  1 
ATOM   4869  C  CG  . GLN C 1 19  ? -3.492  62.805  -71.537 1.00 30.76  ? 19  GLN D CG  1 
ATOM   4870  C  CD  . GLN C 1 19  ? -2.844  61.658  -72.281 1.00 37.51  ? 19  GLN D CD  1 
ATOM   4871  O  OE1 . GLN C 1 19  ? -3.461  61.058  -73.168 1.00 41.03  ? 19  GLN D OE1 1 
ATOM   4872  N  NE2 . GLN C 1 19  ? -1.614  61.328  -71.921 1.00 41.13  ? 19  GLN D NE2 1 
ATOM   4873  N  N   . VAL C 1 20  ? -4.647  65.328  -69.490 1.00 23.15  ? 20  VAL D N   1 
ATOM   4874  C  CA  . VAL C 1 20  ? -3.961  66.552  -69.108 1.00 22.60  ? 20  VAL D CA  1 
ATOM   4875  C  C   . VAL C 1 20  ? -2.543  66.185  -68.707 1.00 26.06  ? 20  VAL D C   1 
ATOM   4876  O  O   . VAL C 1 20  ? -2.336  65.284  -67.885 1.00 26.54  ? 20  VAL D O   1 
ATOM   4877  C  CB  . VAL C 1 20  ? -4.664  67.288  -67.948 1.00 20.81  ? 20  VAL D CB  1 
ATOM   4878  C  CG1 . VAL C 1 20  ? -3.930  68.564  -67.628 1.00 21.53  ? 20  VAL D CG1 1 
ATOM   4879  C  CG2 . VAL C 1 20  ? -6.091  67.595  -68.287 1.00 21.46  ? 20  VAL D CG2 1 
ATOM   4880  N  N   . THR C 1 21  ? -1.572  66.861  -69.304 1.00 28.32  ? 21  THR D N   1 
ATOM   4881  C  CA  . THR C 1 21  ? -0.172  66.686  -68.967 1.00 30.45  ? 21  THR D CA  1 
ATOM   4882  C  C   . THR C 1 21  ? 0.391   68.027  -68.526 1.00 31.38  ? 21  THR D C   1 
ATOM   4883  O  O   . THR C 1 21  ? 0.069   69.070  -69.105 1.00 31.12  ? 21  THR D O   1 
ATOM   4884  C  CB  . THR C 1 21  ? 0.646   66.146  -70.151 1.00 31.47  ? 21  THR D CB  1 
ATOM   4885  O  OG1 . THR C 1 21  ? 0.161   64.858  -70.527 1.00 31.89  ? 21  THR D OG1 1 
ATOM   4886  C  CG2 . THR C 1 21  ? 2.134   66.051  -69.796 1.00 31.12  ? 21  THR D CG2 1 
ATOM   4887  N  N   . CYS C 1 22  ? 1.233   67.998  -67.498 1.00 34.74  ? 22  CYS D N   1 
ATOM   4888  C  CA  . CYS C 1 22  ? 1.931   69.201  -67.055 1.00 33.72  ? 22  CYS D CA  1 
ATOM   4889  C  C   . CYS C 1 22  ? 3.324   68.768  -66.609 1.00 38.09  ? 22  CYS D C   1 
ATOM   4890  O  O   . CYS C 1 22  ? 3.502   68.259  -65.498 1.00 37.76  ? 22  CYS D O   1 
ATOM   4891  C  CB  . CYS C 1 22  ? 1.160   69.905  -65.948 1.00 32.96  ? 22  CYS D CB  1 
ATOM   4892  S  SG  . CYS C 1 22  ? 1.762   71.558  -65.600 1.00 35.80  ? 22  CYS D SG  1 
ATOM   4893  N  N   . GLY C 1 23  ? 4.315   69.001  -67.468 1.00 32.42  ? 23  GLY D N   1 
ATOM   4894  C  CA  . GLY C 1 23  ? 5.640   68.481  -67.222 1.00 33.80  ? 23  GLY D CA  1 
ATOM   4895  C  C   . GLY C 1 23  ? 5.688   66.984  -67.427 1.00 38.18  ? 23  GLY D C   1 
ATOM   4896  O  O   . GLY C 1 23  ? 5.313   66.494  -68.494 1.00 40.99  ? 23  GLY D O   1 
ATOM   4897  N  N   . THR C 1 24  ? 6.103   66.235  -66.410 1.00 38.15  ? 24  THR D N   1 
ATOM   4898  C  CA  . THR C 1 24  ? 6.179   64.784  -66.520 1.00 44.83  ? 24  THR D CA  1 
ATOM   4899  C  C   . THR C 1 24  ? 4.981   64.085  -65.887 1.00 43.38  ? 24  THR D C   1 
ATOM   4900  O  O   . THR C 1 24  ? 5.002   62.858  -65.728 1.00 34.36  ? 24  THR D O   1 
ATOM   4901  C  CB  . THR C 1 24  ? 7.476   64.263  -65.894 1.00 45.45  ? 24  THR D CB  1 
ATOM   4902  O  OG1 . THR C 1 24  ? 7.641   64.810  -64.575 1.00 39.33  ? 24  THR D OG1 1 
ATOM   4903  C  CG2 . THR C 1 24  ? 8.666   64.649  -66.770 1.00 39.58  ? 24  THR D CG2 1 
ATOM   4904  N  N   . THR C 1 25  ? 3.959   64.843  -65.494 1.00 40.25  ? 25  THR D N   1 
ATOM   4905  C  CA  . THR C 1 25  ? 2.760   64.291  -64.884 1.00 34.78  ? 25  THR D CA  1 
ATOM   4906  C  C   . THR C 1 25  ? 1.606   64.272  -65.875 1.00 29.36  ? 25  THR D C   1 
ATOM   4907  O  O   . THR C 1 25  ? 1.262   65.294  -66.473 1.00 32.29  ? 25  THR D O   1 
ATOM   4908  C  CB  . THR C 1 25  ? 2.376   65.093  -63.650 1.00 37.73  ? 25  THR D CB  1 
ATOM   4909  O  OG1 . THR C 1 25  ? 3.549   65.298  -62.847 1.00 40.94  ? 25  THR D OG1 1 
ATOM   4910  C  CG2 . THR C 1 25  ? 1.316   64.327  -62.848 1.00 29.76  ? 25  THR D CG2 1 
ATOM   4911  N  N   . THR C 1 26  ? 0.987   63.115  -66.003 1.00 35.44  ? 26  THR D N   1 
ATOM   4912  C  CA  . THR C 1 26  ? -0.151  62.893  -66.881 1.00 32.52  ? 26  THR D CA  1 
ATOM   4913  C  C   . THR C 1 26  ? -1.282  62.297  -66.059 1.00 31.04  ? 26  THR D C   1 
ATOM   4914  O  O   . THR C 1 26  ? -1.057  61.361  -65.281 1.00 28.82  ? 26  THR D O   1 
ATOM   4915  C  CB  . THR C 1 26  ? 0.258   61.945  -68.017 1.00 29.69  ? 26  THR D CB  1 
ATOM   4916  O  OG1 . THR C 1 26  ? 1.199   62.609  -68.858 1.00 29.56  ? 26  THR D OG1 1 
ATOM   4917  C  CG2 . THR C 1 26  ? -0.931  61.431  -68.802 1.00 29.27  ? 26  THR D CG2 1 
ATOM   4918  N  N   . LEU C 1 27  ? -2.484  62.836  -66.224 1.00 23.88  ? 27  LEU D N   1 
ATOM   4919  C  CA  . LEU C 1 27  ? -3.669  62.258  -65.601 1.00 25.71  ? 27  LEU D CA  1 
ATOM   4920  C  C   . LEU C 1 27  ? -4.887  62.617  -66.443 1.00 25.03  ? 27  LEU D C   1 
ATOM   4921  O  O   . LEU C 1 27  ? -4.760  63.159  -67.546 1.00 22.18  ? 27  LEU D O   1 
ATOM   4922  C  CB  . LEU C 1 27  ? -3.767  62.727  -64.143 1.00 26.32  ? 27  LEU D CB  1 
ATOM   4923  C  CG  . LEU C 1 27  ? -3.414  64.200  -63.903 1.00 30.04  ? 27  LEU D CG  1 
ATOM   4924  C  CD1 . LEU C 1 27  ? -4.387  65.160  -64.597 1.00 26.86  ? 27  LEU D CD1 1 
ATOM   4925  C  CD2 . LEU C 1 27  ? -3.368  64.469  -62.402 1.00 25.43  ? 27  LEU D CD2 1 
ATOM   4926  N  N   . ASN C 1 28  ? -6.070  62.356  -65.902 1.00 17.52  ? 28  ASN D N   1 
ATOM   4927  C  CA  . ASN C 1 28  ? -7.309  62.546  -66.638 1.00 20.59  ? 28  ASN D CA  1 
ATOM   4928  C  C   . ASN C 1 28  ? -7.946  63.877  -66.270 1.00 20.82  ? 28  ASN D C   1 
ATOM   4929  O  O   . ASN C 1 28  ? -7.868  64.325  -65.124 1.00 22.61  ? 28  ASN D O   1 
ATOM   4930  C  CB  . ASN C 1 28  ? -8.304  61.425  -66.320 1.00 19.46  ? 28  ASN D CB  1 
ATOM   4931  C  CG  . ASN C 1 28  ? -7.734  60.054  -66.549 1.00 22.17  ? 28  ASN D CG  1 
ATOM   4932  O  OD1 . ASN C 1 28  ? -7.695  59.570  -67.675 1.00 23.43  ? 28  ASN D OD1 1 
ATOM   4933  N  ND2 . ASN C 1 28  ? -7.228  59.436  -65.479 1.00 18.69  ? 28  ASN D ND2 1 
ATOM   4934  N  N   . GLY C 1 29  ? -8.657  64.464  -67.231 1.00 20.44  ? 29  GLY D N   1 
ATOM   4935  C  CA  . GLY C 1 29  ? -9.440  65.654  -66.974 1.00 20.13  ? 29  GLY D CA  1 
ATOM   4936  C  C   . GLY C 1 29  ? -10.855 65.487  -67.494 1.00 17.88  ? 29  GLY D C   1 
ATOM   4937  O  O   . GLY C 1 29  ? -11.141 64.623  -68.333 1.00 23.27  ? 29  GLY D O   1 
ATOM   4938  N  N   . LEU C 1 30  ? -11.744 66.328  -66.994 1.00 19.21  ? 30  LEU D N   1 
ATOM   4939  C  CA  . LEU C 1 30  ? -13.152 66.253  -67.367 1.00 20.36  ? 30  LEU D CA  1 
ATOM   4940  C  C   . LEU C 1 30  ? -13.521 67.501  -68.150 1.00 20.67  ? 30  LEU D C   1 
ATOM   4941  O  O   . LEU C 1 30  ? -13.538 68.605  -67.594 1.00 19.30  ? 30  LEU D O   1 
ATOM   4942  C  CB  . LEU C 1 30  ? -14.038 66.091  -66.130 1.00 16.16  ? 30  LEU D CB  1 
ATOM   4943  C  CG  . LEU C 1 30  ? -15.532 65.872  -66.351 1.00 16.15  ? 30  LEU D CG  1 
ATOM   4944  C  CD1 . LEU C 1 30  ? -15.783 64.498  -66.928 1.00 18.33  ? 30  LEU D CD1 1 
ATOM   4945  C  CD2 . LEU C 1 30  ? -16.254 66.032  -65.031 1.00 16.09  ? 30  LEU D CD2 1 
ATOM   4946  N  N   . TRP C 1 31  ? -13.873 67.308  -69.416 1.00 21.18  ? 31  TRP D N   1 
ATOM   4947  C  CA  . TRP C 1 31  ? -14.099 68.395  -70.359 1.00 21.17  ? 31  TRP D CA  1 
ATOM   4948  C  C   . TRP C 1 31  ? -15.600 68.649  -70.454 1.00 22.83  ? 31  TRP D C   1 
ATOM   4949  O  O   . TRP C 1 31  ? -16.344 67.818  -70.989 1.00 25.12  ? 31  TRP D O   1 
ATOM   4950  C  CB  . TRP C 1 31  ? -13.501 68.031  -71.715 1.00 23.30  ? 31  TRP D CB  1 
ATOM   4951  C  CG  . TRP C 1 31  ? -13.567 69.097  -72.784 1.00 27.71  ? 31  TRP D CG  1 
ATOM   4952  C  CD1 . TRP C 1 31  ? -13.777 70.434  -72.609 1.00 22.84  ? 31  TRP D CD1 1 
ATOM   4953  C  CD2 . TRP C 1 31  ? -13.415 68.897  -74.198 1.00 24.48  ? 31  TRP D CD2 1 
ATOM   4954  N  NE1 . TRP C 1 31  ? -13.765 71.076  -73.826 1.00 29.76  ? 31  TRP D NE1 1 
ATOM   4955  C  CE2 . TRP C 1 31  ? -13.544 70.153  -74.816 1.00 29.17  ? 31  TRP D CE2 1 
ATOM   4956  C  CE3 . TRP C 1 31  ? -13.172 67.777  -74.998 1.00 22.46  ? 31  TRP D CE3 1 
ATOM   4957  C  CZ2 . TRP C 1 31  ? -13.431 70.319  -76.202 1.00 29.79  ? 31  TRP D CZ2 1 
ATOM   4958  C  CZ3 . TRP C 1 31  ? -13.069 67.940  -76.366 1.00 22.42  ? 31  TRP D CZ3 1 
ATOM   4959  C  CH2 . TRP C 1 31  ? -13.194 69.193  -76.957 1.00 24.32  ? 31  TRP D CH2 1 
ATOM   4960  N  N   . LEU C 1 32  ? -16.046 69.774  -69.886 1.00 21.68  ? 32  LEU D N   1 
ATOM   4961  C  CA  . LEU C 1 32  ? -17.448 70.186  -69.892 1.00 21.27  ? 32  LEU D CA  1 
ATOM   4962  C  C   . LEU C 1 32  ? -17.544 71.639  -70.338 1.00 24.22  ? 32  LEU D C   1 
ATOM   4963  O  O   . LEU C 1 32  ? -16.906 72.516  -69.736 1.00 22.34  ? 32  LEU D O   1 
ATOM   4964  C  CB  . LEU C 1 32  ? -18.063 70.025  -68.498 1.00 22.78  ? 32  LEU D CB  1 
ATOM   4965  C  CG  . LEU C 1 32  ? -17.913 68.631  -67.871 1.00 18.70  ? 32  LEU D CG  1 
ATOM   4966  C  CD1 . LEU C 1 32  ? -18.177 68.725  -66.396 1.00 16.24  ? 32  LEU D CD1 1 
ATOM   4967  C  CD2 . LEU C 1 32  ? -18.799 67.568  -68.540 1.00 14.56  ? 32  LEU D CD2 1 
ATOM   4968  N  N   . ASP C 1 33  ? -18.345 71.897  -71.370 1.00 21.99  ? 33  ASP D N   1 
ATOM   4969  C  CA  . ASP C 1 33  ? -18.432 73.232  -72.008 1.00 32.40  ? 33  ASP D CA  1 
ATOM   4970  C  C   . ASP C 1 33  ? -17.012 73.616  -72.434 1.00 24.27  ? 33  ASP D C   1 
ATOM   4971  O  O   . ASP C 1 33  ? -16.343 72.827  -73.121 1.00 25.52  ? 33  ASP D O   1 
ATOM   4972  C  CB  . ASP C 1 33  ? -19.152 74.224  -71.076 1.00 27.47  ? 33  ASP D CB  1 
ATOM   4973  C  CG  . ASP C 1 33  ? -20.553 73.725  -70.621 1.00 39.40  ? 33  ASP D CG  1 
ATOM   4974  O  OD1 . ASP C 1 33  ? -21.324 73.223  -71.481 1.00 41.17  ? 33  ASP D OD1 1 
ATOM   4975  O  OD2 . ASP C 1 33  ? -20.880 73.812  -69.400 1.00 37.53  ? 33  ASP D OD2 1 
ATOM   4976  N  N   . ASP C 1 34  ? -16.492 74.781  -72.062 1.00 21.35  ? 34  ASP D N   1 
ATOM   4977  C  CA  . ASP C 1 34  ? -15.158 75.164  -72.516 1.00 27.76  ? 34  ASP D CA  1 
ATOM   4978  C  C   . ASP C 1 34  ? -14.126 75.108  -71.389 1.00 26.22  ? 34  ASP D C   1 
ATOM   4979  O  O   . ASP C 1 34  ? -13.112 75.819  -71.429 1.00 33.51  ? 34  ASP D O   1 
ATOM   4980  C  CB  . ASP C 1 34  ? -15.168 76.554  -73.156 1.00 26.00  ? 34  ASP D CB  1 
ATOM   4981  C  CG  . ASP C 1 34  ? -15.554 77.644  -72.175 1.00 28.89  ? 34  ASP D CG  1 
ATOM   4982  O  OD1 . ASP C 1 34  ? -16.309 77.372  -71.215 1.00 28.09  ? 34  ASP D OD1 1 
ATOM   4983  O  OD2 . ASP C 1 34  ? -15.047 78.770  -72.335 1.00 30.43  ? 34  ASP D OD2 1 
ATOM   4984  N  N   . VAL C 1 35  ? -14.356 74.251  -70.396 1.00 26.22  ? 35  VAL D N   1 
ATOM   4985  C  CA  . VAL C 1 35  ? -13.488 74.109  -69.235 1.00 22.26  ? 35  VAL D CA  1 
ATOM   4986  C  C   . VAL C 1 35  ? -13.117 72.645  -69.047 1.00 23.96  ? 35  VAL D C   1 
ATOM   4987  O  O   . VAL C 1 35  ? -13.976 71.762  -69.122 1.00 26.69  ? 35  VAL D O   1 
ATOM   4988  C  CB  . VAL C 1 35  ? -14.170 74.636  -67.957 1.00 21.31  ? 35  VAL D CB  1 
ATOM   4989  C  CG1 . VAL C 1 35  ? -13.285 74.412  -66.753 1.00 18.87  ? 35  VAL D CG1 1 
ATOM   4990  C  CG2 . VAL C 1 35  ? -14.529 76.113  -68.118 1.00 29.52  ? 35  VAL D CG2 1 
ATOM   4991  N  N   . VAL C 1 36  ? -11.853 72.394  -68.737 1.00 22.21  ? 36  VAL D N   1 
ATOM   4992  C  CA  . VAL C 1 36  ? -11.376 71.072  -68.362 1.00 20.67  ? 36  VAL D CA  1 
ATOM   4993  C  C   . VAL C 1 36  ? -11.020 71.101  -66.887 1.00 22.07  ? 36  VAL D C   1 
ATOM   4994  O  O   . VAL C 1 36  ? -10.244 71.959  -66.445 1.00 19.51  ? 36  VAL D O   1 
ATOM   4995  C  CB  . VAL C 1 36  ? -10.177 70.638  -69.220 1.00 20.85  ? 36  VAL D CB  1 
ATOM   4996  C  CG1 . VAL C 1 36  ? -9.513  69.406  -68.636 1.00 16.05  ? 36  VAL D CG1 1 
ATOM   4997  C  CG2 . VAL C 1 36  ? -10.638 70.412  -70.649 1.00 15.53  ? 36  VAL D CG2 1 
ATOM   4998  N  N   . TYR C 1 37  ? -11.615 70.175  -66.130 1.00 21.84  ? 37  TYR D N   1 
ATOM   4999  C  CA  . TYR C 1 37  ? -11.372 70.002  -64.708 1.00 22.14  ? 37  TYR D CA  1 
ATOM   5000  C  C   . TYR C 1 37  ? -10.451 68.812  -64.508 1.00 22.98  ? 37  TYR D C   1 
ATOM   5001  O  O   . TYR C 1 37  ? -10.655 67.756  -65.104 1.00 26.87  ? 37  TYR D O   1 
ATOM   5002  C  CB  . TYR C 1 37  ? -12.675 69.752  -63.940 1.00 22.09  ? 37  TYR D CB  1 
ATOM   5003  C  CG  . TYR C 1 37  ? -13.748 70.783  -64.181 1.00 27.50  ? 37  TYR D CG  1 
ATOM   5004  C  CD1 . TYR C 1 37  ? -14.502 70.771  -65.348 1.00 24.78  ? 37  TYR D CD1 1 
ATOM   5005  C  CD2 . TYR C 1 37  ? -14.013 71.773  -63.239 1.00 27.21  ? 37  TYR D CD2 1 
ATOM   5006  C  CE1 . TYR C 1 37  ? -15.476 71.714  -65.574 1.00 24.20  ? 37  TYR D CE1 1 
ATOM   5007  C  CE2 . TYR C 1 37  ? -14.986 72.726  -63.464 1.00 23.90  ? 37  TYR D CE2 1 
ATOM   5008  C  CZ  . TYR C 1 37  ? -15.707 72.692  -64.631 1.00 25.60  ? 37  TYR D CZ  1 
ATOM   5009  O  OH  . TYR C 1 37  ? -16.687 73.622  -64.859 1.00 27.67  ? 37  TYR D OH  1 
ATOM   5010  N  N   . CYS C 1 38  ? -9.470  68.975  -63.636 1.00 18.14  ? 38  CYS D N   1 
ATOM   5011  C  CA  . CYS C 1 38  ? -8.515  67.928  -63.321 1.00 22.38  ? 38  CYS D CA  1 
ATOM   5012  C  C   . CYS C 1 38  ? -7.987  68.201  -61.920 1.00 23.96  ? 38  CYS D C   1 
ATOM   5013  O  O   . CYS C 1 38  ? -8.209  69.289  -61.376 1.00 24.68  ? 38  CYS D O   1 
ATOM   5014  C  CB  . CYS C 1 38  ? -7.372  67.879  -64.348 1.00 23.34  ? 38  CYS D CB  1 
ATOM   5015  S  SG  . CYS C 1 38  ? -6.222  69.307  -64.383 1.00 27.60  ? 38  CYS D SG  1 
ATOM   5016  N  N   . PRO C 1 39  ? -7.337  67.214  -61.300 1.00 18.27  ? 39  PRO D N   1 
ATOM   5017  C  CA  . PRO C 1 39  ? -6.749  67.456  -59.976 1.00 19.94  ? 39  PRO D CA  1 
ATOM   5018  C  C   . PRO C 1 39  ? -5.585  68.426  -60.076 1.00 21.23  ? 39  PRO D C   1 
ATOM   5019  O  O   . PRO C 1 39  ? -4.785  68.372  -61.016 1.00 17.30  ? 39  PRO D O   1 
ATOM   5020  C  CB  . PRO C 1 39  ? -6.283  66.061  -59.525 1.00 18.27  ? 39  PRO D CB  1 
ATOM   5021  C  CG  . PRO C 1 39  ? -7.045  65.109  -60.354 1.00 21.76  ? 39  PRO D CG  1 
ATOM   5022  C  CD  . PRO C 1 39  ? -7.237  65.804  -61.684 1.00 22.17  ? 39  PRO D CD  1 
ATOM   5023  N  N   . ARG C 1 40  ? -5.504  69.331  -59.095 1.00 21.62  ? 40  ARG D N   1 
ATOM   5024  C  CA  . ARG C 1 40  ? -4.465  70.355  -59.139 1.00 22.61  ? 40  ARG D CA  1 
ATOM   5025  C  C   . ARG C 1 40  ? -3.064  69.764  -59.014 1.00 25.35  ? 40  ARG D C   1 
ATOM   5026  O  O   . ARG C 1 40  ? -2.101  70.363  -59.513 1.00 24.31  ? 40  ARG D O   1 
ATOM   5027  C  CB  . ARG C 1 40  ? -4.698  71.400  -58.045 1.00 22.83  ? 40  ARG D CB  1 
ATOM   5028  C  CG  . ARG C 1 40  ? -4.470  70.899  -56.621 1.00 21.81  ? 40  ARG D CG  1 
ATOM   5029  C  CD  . ARG C 1 40  ? -4.662  72.027  -55.624 1.00 25.86  ? 40  ARG D CD  1 
ATOM   5030  N  NE  . ARG C 1 40  ? -4.605  71.593  -54.230 1.00 32.46  ? 40  ARG D NE  1 
ATOM   5031  C  CZ  . ARG C 1 40  ? -4.672  72.420  -53.189 1.00 34.66  ? 40  ARG D CZ  1 
ATOM   5032  N  NH1 . ARG C 1 40  ? -4.760  73.739  -53.345 1.00 32.50  ? 40  ARG D NH1 1 
ATOM   5033  N  NH2 . ARG C 1 40  ? -4.643  71.919  -51.963 1.00 35.00  ? 40  ARG D NH2 1 
ATOM   5034  N  N   . HIS C 1 41  ? -2.914  68.582  -58.355 1.00 26.41  ? 41  HIS D N   1 
ATOM   5035  C  CA  . HIS C 1 41  ? -1.537  68.059  -58.243 1.00 21.63  ? 41  HIS D CA  1 
ATOM   5036  C  C   . HIS C 1 41  ? -0.996  67.528  -59.573 1.00 22.41  ? 41  HIS D C   1 
ATOM   5037  O  O   . HIS C 1 41  ? 0.063   66.916  -59.589 1.00 22.86  ? 41  HIS D O   1 
ATOM   5038  C  CB  . HIS C 1 41  ? -1.436  66.983  -57.160 1.00 26.44  ? 41  HIS D CB  1 
ATOM   5039  C  CG  . HIS C 1 41  ? -2.183  65.728  -57.478 1.00 25.62  ? 41  HIS D CG  1 
ATOM   5040  N  ND1 . HIS C 1 41  ? -3.442  65.472  -56.982 1.00 27.28  ? 41  HIS D ND1 1 
ATOM   5041  C  CD2 . HIS C 1 41  ? -1.839  64.644  -58.217 1.00 25.99  ? 41  HIS D CD2 1 
ATOM   5042  C  CE1 . HIS C 1 41  ? -3.852  64.289  -57.418 1.00 28.02  ? 41  HIS D CE1 1 
ATOM   5043  N  NE2 . HIS C 1 41  ? -2.895  63.765  -58.167 1.00 25.53  ? 41  HIS D NE2 1 
ATOM   5044  N  N   . VAL C 1 42  ? -1.675  67.739  -60.704 1.00 24.12  ? 42  VAL D N   1 
ATOM   5045  C  CA  . VAL C 1 42  ? -1.010  67.584  -61.997 1.00 28.95  ? 42  VAL D CA  1 
ATOM   5046  C  C   . VAL C 1 42  ? 0.183   68.527  -62.122 1.00 31.05  ? 42  VAL D C   1 
ATOM   5047  O  O   . VAL C 1 42  ? 1.086   68.276  -62.928 1.00 31.52  ? 42  VAL D O   1 
ATOM   5048  C  CB  . VAL C 1 42  ? -1.993  67.824  -63.162 1.00 26.76  ? 42  VAL D CB  1 
ATOM   5049  C  CG1 . VAL C 1 42  ? -2.342  69.298  -63.265 1.00 24.90  ? 42  VAL D CG1 1 
ATOM   5050  C  CG2 . VAL C 1 42  ? -1.406  67.316  -64.479 1.00 24.61  ? 42  VAL D CG2 1 
ATOM   5051  N  N   . ILE C 1 43  ? 0.215   69.617  -61.343 1.00 28.27  ? 43  ILE D N   1 
ATOM   5052  C  CA  . ILE C 1 43  ? 1.305   70.584  -61.445 1.00 35.25  ? 43  ILE D CA  1 
ATOM   5053  C  C   . ILE C 1 43  ? 2.462   70.246  -60.520 1.00 35.76  ? 43  ILE D C   1 
ATOM   5054  O  O   . ILE C 1 43  ? 3.457   70.980  -60.495 1.00 42.69  ? 43  ILE D O   1 
ATOM   5055  C  CB  . ILE C 1 43  ? 0.821   72.037  -61.220 1.00 31.93  ? 43  ILE D CB  1 
ATOM   5056  C  CG1 . ILE C 1 43  ? 0.548   72.324  -59.740 1.00 33.83  ? 43  ILE D CG1 1 
ATOM   5057  C  CG2 . ILE C 1 43  ? -0.392  72.330  -62.089 1.00 34.31  ? 43  ILE D CG2 1 
ATOM   5058  C  CD1 . ILE C 1 43  ? -0.077  73.692  -59.474 1.00 32.42  ? 43  ILE D CD1 1 
ATOM   5059  N  N   . CYS C 1 44  ? 2.355   69.174  -59.744 1.00 41.01  ? 44  CYS D N   1 
ATOM   5060  C  CA  . CYS C 1 44  ? 3.435   68.741  -58.875 1.00 40.97  ? 44  CYS D CA  1 
ATOM   5061  C  C   . CYS C 1 44  ? 4.405   67.835  -59.619 1.00 47.88  ? 44  CYS D C   1 
ATOM   5062  O  O   . CYS C 1 44  ? 4.031   67.103  -60.541 1.00 42.31  ? 44  CYS D O   1 
ATOM   5063  C  CB  . CYS C 1 44  ? 2.883   67.994  -57.665 1.00 44.91  ? 44  CYS D CB  1 
ATOM   5064  S  SG  . CYS C 1 44  ? 1.803   68.992  -56.654 1.00 47.99  ? 44  CYS D SG  1 
ATOM   5065  N  N   . THR C 1 45  ? 5.659   67.880  -59.193 1.00 61.40  ? 45  THR D N   1 
ATOM   5066  C  CA  . THR C 1 45  ? 6.615   66.845  -59.534 1.00 66.77  ? 45  THR D CA  1 
ATOM   5067  C  C   . THR C 1 45  ? 6.531   65.741  -58.487 1.00 76.98  ? 45  THR D C   1 
ATOM   5068  O  O   . THR C 1 45  ? 5.921   65.903  -57.429 1.00 79.53  ? 45  THR D O   1 
ATOM   5069  C  CB  . THR C 1 45  ? 8.030   67.421  -59.597 1.00 73.01  ? 45  THR D CB  1 
ATOM   5070  O  OG1 . THR C 1 45  ? 8.505   67.669  -58.266 1.00 80.47  ? 45  THR D OG1 1 
ATOM   5071  C  CG2 . THR C 1 45  ? 8.030   68.740  -60.372 1.00 69.29  ? 45  THR D CG2 1 
ATOM   5072  N  N   . SER C 1 46  ? 7.143   64.595  -58.793 1.00 89.73  ? 46  SER D N   1 
ATOM   5073  C  CA  . SER C 1 46  ? 7.212   63.533  -57.792 1.00 93.46  ? 46  SER D CA  1 
ATOM   5074  C  C   . SER C 1 46  ? 8.017   63.977  -56.575 1.00 89.82  ? 46  SER D C   1 
ATOM   5075  O  O   . SER C 1 46  ? 7.765   63.515  -55.457 1.00 89.86  ? 46  SER D O   1 
ATOM   5076  C  CB  . SER C 1 46  ? 7.807   62.259  -58.402 1.00 92.47  ? 46  SER D CB  1 
ATOM   5077  O  OG  . SER C 1 46  ? 6.854   61.573  -59.203 1.00 88.86  ? 46  SER D OG  1 
ATOM   5078  N  N   . GLU C 1 47  ? 8.969   64.887  -56.769 1.00 86.55  ? 47  GLU D N   1 
ATOM   5079  C  CA  . GLU C 1 47  ? 9.768   65.412  -55.673 1.00 87.69  ? 47  GLU D CA  1 
ATOM   5080  C  C   . GLU C 1 47  ? 8.903   66.180  -54.686 1.00 95.14  ? 47  GLU D C   1 
ATOM   5081  O  O   . GLU C 1 47  ? 8.726   65.753  -53.540 1.00 95.71  ? 47  GLU D O   1 
ATOM   5082  C  CB  . GLU C 1 47  ? 10.865  66.328  -56.211 1.00 90.10  ? 47  GLU D CB  1 
ATOM   5083  C  CG  . GLU C 1 47  ? 11.684  65.719  -57.323 1.00 91.07  ? 47  GLU D CG  1 
ATOM   5084  C  CD  . GLU C 1 47  ? 12.237  66.770  -58.265 1.00 88.85  ? 47  GLU D CD  1 
ATOM   5085  O  OE1 . GLU C 1 47  ? 11.678  67.892  -58.313 1.00 83.92  ? 47  GLU D OE1 1 
ATOM   5086  O  OE2 . GLU C 1 47  ? 13.226  66.471  -58.963 1.00 86.08  ? 47  GLU D OE2 1 
ATOM   5087  N  N   . ASP C 1 48  ? 8.351   67.310  -55.133 1.00 93.87  ? 48  ASP D N   1 
ATOM   5088  C  CA  . ASP C 1 48  ? 7.680   68.256  -54.249 1.00 88.22  ? 48  ASP D CA  1 
ATOM   5089  C  C   . ASP C 1 48  ? 6.271   67.839  -53.838 1.00 88.64  ? 48  ASP D C   1 
ATOM   5090  O  O   . ASP C 1 48  ? 5.423   68.694  -53.564 1.00 77.93  ? 48  ASP D O   1 
ATOM   5091  C  CB  . ASP C 1 48  ? 7.638   69.623  -54.923 1.00 96.64  ? 48  ASP D CB  1 
ATOM   5092  C  CG  . ASP C 1 48  ? 8.959   70.341  -54.826 1.00 99.99  ? 48  ASP D CG  1 
ATOM   5093  O  OD1 . ASP C 1 48  ? 9.932   69.699  -54.369 1.00 93.99  ? 48  ASP D OD1 1 
ATOM   5094  O  OD2 . ASP C 1 48  ? 9.023   71.534  -55.194 1.00 94.66  ? 48  ASP D OD2 1 
ATOM   5095  N  N   . MET C 1 49  ? 6.018   66.535  -53.746 1.00 93.38  ? 49  MET D N   1 
ATOM   5096  C  CA  . MET C 1 49  ? 4.737   66.050  -53.249 1.00 88.22  ? 49  MET D CA  1 
ATOM   5097  C  C   . MET C 1 49  ? 4.689   66.011  -51.730 1.00 84.96  ? 49  MET D C   1 
ATOM   5098  O  O   . MET C 1 49  ? 3.602   65.863  -51.161 1.00 83.65  ? 49  MET D O   1 
ATOM   5099  C  CB  . MET C 1 49  ? 4.433   64.656  -53.805 1.00 89.76  ? 49  MET D CB  1 
ATOM   5100  C  CG  . MET C 1 49  ? 3.764   64.646  -55.173 1.00 90.63  ? 49  MET D CG  1 
ATOM   5101  S  SD  . MET C 1 49  ? 2.050   65.211  -55.107 1.00 86.07  ? 49  MET D SD  1 
ATOM   5102  C  CE  . MET C 1 49  ? 1.502   64.792  -56.761 1.00 78.14  ? 49  MET D CE  1 
ATOM   5103  N  N   . LEU C 1 50  ? 5.842   66.139  -51.072 1.00 85.61  ? 50  LEU D N   1 
ATOM   5104  C  CA  . LEU C 1 50  ? 5.898   66.042  -49.618 1.00 84.38  ? 50  LEU D CA  1 
ATOM   5105  C  C   . LEU C 1 50  ? 5.161   67.203  -48.957 1.00 83.44  ? 50  LEU D C   1 
ATOM   5106  O  O   . LEU C 1 50  ? 4.387   67.000  -48.015 1.00 85.06  ? 50  LEU D O   1 
ATOM   5107  C  CB  . LEU C 1 50  ? 7.360   65.973  -49.170 1.00 89.74  ? 50  LEU D CB  1 
ATOM   5108  C  CG  . LEU C 1 50  ? 7.989   64.584  -49.370 1.00 90.52  ? 50  LEU D CG  1 
ATOM   5109  C  CD1 . LEU C 1 50  ? 9.462   64.561  -48.979 1.00 89.29  ? 50  LEU D CD1 1 
ATOM   5110  C  CD2 . LEU C 1 50  ? 7.207   63.500  -48.620 1.00 81.22  ? 50  LEU D CD2 1 
ATOM   5111  N  N   . ASN C 1 51  ? 5.391   68.426  -49.430 1.00 80.21  ? 51  ASN D N   1 
ATOM   5112  C  CA  . ASN C 1 51  ? 4.708   69.605  -48.894 1.00 75.15  ? 51  ASN D CA  1 
ATOM   5113  C  C   . ASN C 1 51  ? 4.566   70.647  -49.993 1.00 74.49  ? 51  ASN D C   1 
ATOM   5114  O  O   . ASN C 1 51  ? 5.355   71.591  -50.089 1.00 73.76  ? 51  ASN D O   1 
ATOM   5115  C  CB  . ASN C 1 51  ? 5.450   70.171  -47.686 1.00 82.02  ? 51  ASN D CB  1 
ATOM   5116  C  CG  . ASN C 1 51  ? 4.810   69.751  -46.377 1.00 92.83  ? 51  ASN D CG  1 
ATOM   5117  O  OD1 . ASN C 1 51  ? 3.835   70.358  -45.927 1.00 88.92  ? 51  ASN D OD1 1 
ATOM   5118  N  ND2 . ASN C 1 51  ? 5.337   68.686  -45.773 1.00 95.58  ? 51  ASN D ND2 1 
ATOM   5119  N  N   . PRO C 1 52  ? 3.556   70.495  -50.855 1.00 72.61  ? 52  PRO D N   1 
ATOM   5120  C  CA  . PRO C 1 52  ? 3.437   71.380  -52.026 1.00 62.86  ? 52  PRO D CA  1 
ATOM   5121  C  C   . PRO C 1 52  ? 2.715   72.682  -51.701 1.00 53.04  ? 52  PRO D C   1 
ATOM   5122  O  O   . PRO C 1 52  ? 1.656   72.685  -51.074 1.00 55.82  ? 52  PRO D O   1 
ATOM   5123  C  CB  . PRO C 1 52  ? 2.630   70.537  -53.021 1.00 57.11  ? 52  PRO D CB  1 
ATOM   5124  C  CG  . PRO C 1 52  ? 1.787   69.653  -52.149 1.00 57.76  ? 52  PRO D CG  1 
ATOM   5125  C  CD  . PRO C 1 52  ? 2.556   69.414  -50.872 1.00 66.16  ? 52  PRO D CD  1 
ATOM   5126  N  N   . ASN C 1 53  ? 3.292   73.791  -52.146 1.00 58.01  ? 53  ASN D N   1 
ATOM   5127  C  CA  . ASN C 1 53  ? 2.638   75.102  -52.096 1.00 55.99  ? 53  ASN D CA  1 
ATOM   5128  C  C   . ASN C 1 53  ? 1.987   75.321  -53.461 1.00 50.70  ? 53  ASN D C   1 
ATOM   5129  O  O   . ASN C 1 53  ? 2.611   75.830  -54.392 1.00 49.51  ? 53  ASN D O   1 
ATOM   5130  C  CB  . ASN C 1 53  ? 3.642   76.199  -51.772 1.00 52.95  ? 53  ASN D CB  1 
ATOM   5131  C  CG  . ASN C 1 53  ? 2.981   77.533  -51.499 1.00 53.42  ? 53  ASN D CG  1 
ATOM   5132  O  OD1 . ASN C 1 53  ? 1.891   77.820  -51.991 1.00 54.52  ? 53  ASN D OD1 1 
ATOM   5133  N  ND2 . ASN C 1 53  ? 3.665   78.376  -50.738 1.00 59.30  ? 53  ASN D ND2 1 
ATOM   5134  N  N   . TYR C 1 54  ? 0.711   74.951  -53.573 1.00 48.52  ? 54  TYR D N   1 
ATOM   5135  C  CA  . TYR C 1 54  ? 0.073   74.876  -54.885 1.00 42.84  ? 54  TYR D CA  1 
ATOM   5136  C  C   . TYR C 1 54  ? -0.043  76.245  -55.543 1.00 47.40  ? 54  TYR D C   1 
ATOM   5137  O  O   . TYR C 1 54  ? 0.086   76.361  -56.771 1.00 42.16  ? 54  TYR D O   1 
ATOM   5138  C  CB  . TYR C 1 54  ? -1.294  74.218  -54.752 1.00 38.55  ? 54  TYR D CB  1 
ATOM   5139  C  CG  . TYR C 1 54  ? -1.218  72.717  -54.564 1.00 39.22  ? 54  TYR D CG  1 
ATOM   5140  C  CD1 . TYR C 1 54  ? -0.962  71.875  -55.642 1.00 31.43  ? 54  TYR D CD1 1 
ATOM   5141  C  CD2 . TYR C 1 54  ? -1.394  72.139  -53.307 1.00 39.20  ? 54  TYR D CD2 1 
ATOM   5142  C  CE1 . TYR C 1 54  ? -0.895  70.520  -55.478 1.00 28.62  ? 54  TYR D CE1 1 
ATOM   5143  C  CE2 . TYR C 1 54  ? -1.334  70.773  -53.137 1.00 36.38  ? 54  TYR D CE2 1 
ATOM   5144  C  CZ  . TYR C 1 54  ? -1.082  69.972  -54.227 1.00 36.38  ? 54  TYR D CZ  1 
ATOM   5145  O  OH  . TYR C 1 54  ? -1.008  68.612  -54.078 1.00 38.88  ? 54  TYR D OH  1 
ATOM   5146  N  N   . GLU C 1 55  ? -0.314  77.285  -54.744 1.00 53.32  ? 55  GLU D N   1 
ATOM   5147  C  CA  . GLU C 1 55  ? -0.394  78.639  -55.283 1.00 50.95  ? 55  GLU D CA  1 
ATOM   5148  C  C   . GLU C 1 55  ? 0.927   79.031  -55.930 1.00 46.97  ? 55  GLU D C   1 
ATOM   5149  O  O   . GLU C 1 55  ? 0.948   79.576  -57.039 1.00 42.32  ? 55  GLU D O   1 
ATOM   5150  C  CB  . GLU C 1 55  ? -0.756  79.626  -54.174 1.00 52.04  ? 55  GLU D CB  1 
ATOM   5151  C  CG  . GLU C 1 55  ? -2.110  79.344  -53.503 1.00 57.87  ? 55  GLU D CG  1 
ATOM   5152  C  CD  . GLU C 1 55  ? -2.035  78.149  -52.540 1.00 65.78  ? 55  GLU D CD  1 
ATOM   5153  O  OE1 . GLU C 1 55  ? -0.909  77.656  -52.299 1.00 58.79  ? 55  GLU D OE1 1 
ATOM   5154  O  OE2 . GLU C 1 55  ? -3.092  77.665  -52.065 1.00 67.47  ? 55  GLU D OE2 1 
ATOM   5155  N  N   . ASP C 1 56  ? 2.044   78.727  -55.259 1.00 49.91  ? 56  ASP D N   1 
ATOM   5156  C  CA  . ASP C 1 56  ? 3.360   79.034  -55.806 1.00 48.61  ? 56  ASP D CA  1 
ATOM   5157  C  C   . ASP C 1 56  ? 3.638   78.222  -57.059 1.00 48.12  ? 56  ASP D C   1 
ATOM   5158  O  O   . ASP C 1 56  ? 4.168   78.751  -58.048 1.00 49.19  ? 56  ASP D O   1 
ATOM   5159  C  CB  . ASP C 1 56  ? 4.454   78.770  -54.767 1.00 54.82  ? 56  ASP D CB  1 
ATOM   5160  C  CG  . ASP C 1 56  ? 4.471   79.798  -53.631 1.00 64.38  ? 56  ASP D CG  1 
ATOM   5161  O  OD1 . ASP C 1 56  ? 3.651   80.746  -53.641 1.00 61.57  ? 56  ASP D OD1 1 
ATOM   5162  O  OD2 . ASP C 1 56  ? 5.323   79.657  -52.721 1.00 68.77  ? 56  ASP D OD2 1 
ATOM   5163  N  N   . LEU C 1 57  ? 3.298   76.929  -57.027 1.00 46.63  ? 57  LEU D N   1 
ATOM   5164  C  CA  . LEU C 1 57  ? 3.494   76.076  -58.194 1.00 42.05  ? 57  LEU D CA  1 
ATOM   5165  C  C   . LEU C 1 57  ? 2.660   76.569  -59.368 1.00 34.59  ? 57  LEU D C   1 
ATOM   5166  O  O   . LEU C 1 57  ? 3.115   76.564  -60.516 1.00 37.20  ? 57  LEU D O   1 
ATOM   5167  C  CB  . LEU C 1 57  ? 3.137   74.634  -57.834 1.00 39.03  ? 57  LEU D CB  1 
ATOM   5168  C  CG  . LEU C 1 57  ? 4.054   74.002  -56.781 1.00 42.95  ? 57  LEU D CG  1 
ATOM   5169  C  CD1 . LEU C 1 57  ? 3.457   72.749  -56.147 1.00 41.27  ? 57  LEU D CD1 1 
ATOM   5170  C  CD2 . LEU C 1 57  ? 5.396   73.680  -57.424 1.00 45.59  ? 57  LEU D CD2 1 
ATOM   5171  N  N   . LEU C 1 58  ? 1.457   77.055  -59.089 1.00 32.80  ? 58  LEU D N   1 
ATOM   5172  C  CA  . LEU C 1 58  ? 0.557   77.411  -60.173 1.00 33.16  ? 58  LEU D CA  1 
ATOM   5173  C  C   . LEU C 1 58  ? 1.048   78.647  -60.914 1.00 39.37  ? 58  LEU D C   1 
ATOM   5174  O  O   . LEU C 1 58  ? 0.970   78.704  -62.146 1.00 38.31  ? 58  LEU D O   1 
ATOM   5175  C  CB  . LEU C 1 58  ? -0.848  77.620  -59.621 1.00 30.66  ? 58  LEU D CB  1 
ATOM   5176  C  CG  . LEU C 1 58  ? -1.923  77.767  -60.682 1.00 30.53  ? 58  LEU D CG  1 
ATOM   5177  C  CD1 . LEU C 1 58  ? -1.888  76.559  -61.606 1.00 33.21  ? 58  LEU D CD1 1 
ATOM   5178  C  CD2 . LEU C 1 58  ? -3.282  77.920  -60.027 1.00 31.27  ? 58  LEU D CD2 1 
ATOM   5179  N  N   . ILE C 1 59  ? 1.578   79.641  -60.189 1.00 40.48  ? 59  ILE D N   1 
ATOM   5180  C  CA  . ILE C 1 59  ? 2.027   80.859  -60.851 1.00 39.83  ? 59  ILE D CA  1 
ATOM   5181  C  C   . ILE C 1 59  ? 3.255   80.626  -61.724 1.00 37.13  ? 59  ILE D C   1 
ATOM   5182  O  O   . ILE C 1 59  ? 3.478   81.381  -62.671 1.00 44.82  ? 59  ILE D O   1 
ATOM   5183  C  CB  . ILE C 1 59  ? 2.308   81.994  -59.851 1.00 45.69  ? 59  ILE D CB  1 
ATOM   5184  C  CG1 . ILE C 1 59  ? 2.224   83.307  -60.595 1.00 46.08  ? 59  ILE D CG1 1 
ATOM   5185  C  CG2 . ILE C 1 59  ? 3.731   81.936  -59.364 1.00 46.06  ? 59  ILE D CG2 1 
ATOM   5186  C  CD1 . ILE C 1 59  ? 0.919   83.441  -61.369 1.00 58.38  ? 59  ILE D CD1 1 
ATOM   5187  N  N   . ARG C 1 60  ? 4.034   79.582  -61.481 1.00 37.58  ? 60  ARG D N   1 
ATOM   5188  C  CA  . ARG C 1 60  ? 5.169   79.345  -62.357 1.00 38.23  ? 60  ARG D CA  1 
ATOM   5189  C  C   . ARG C 1 60  ? 4.763   78.724  -63.687 1.00 43.64  ? 60  ARG D C   1 
ATOM   5190  O  O   . ARG C 1 60  ? 5.614   78.594  -64.575 1.00 44.49  ? 60  ARG D O   1 
ATOM   5191  C  CB  . ARG C 1 60  ? 6.193   78.445  -61.667 1.00 38.45  ? 60  ARG D CB  1 
ATOM   5192  C  CG  . ARG C 1 60  ? 6.745   79.052  -60.399 1.00 48.79  ? 60  ARG D CG  1 
ATOM   5193  C  CD  . ARG C 1 60  ? 8.170   78.601  -60.129 1.00 55.07  ? 60  ARG D CD  1 
ATOM   5194  N  NE  . ARG C 1 60  ? 8.184   77.557  -59.113 1.00 67.99  ? 60  ARG D NE  1 
ATOM   5195  C  CZ  . ARG C 1 60  ? 8.196   77.780  -57.804 1.00 69.42  ? 60  ARG D CZ  1 
ATOM   5196  N  NH1 . ARG C 1 60  ? 8.231   79.011  -57.309 1.00 63.28  ? 60  ARG D NH1 1 
ATOM   5197  N  NH2 . ARG C 1 60  ? 8.168   76.742  -56.972 1.00 67.60  ? 60  ARG D NH2 1 
ATOM   5198  N  N   . LYS C 1 61  ? 3.488   78.382  -63.864 1.00 39.31  ? 61  LYS D N   1 
ATOM   5199  C  CA  . LYS C 1 61  ? 3.013   77.757  -65.089 1.00 38.91  ? 61  LYS D CA  1 
ATOM   5200  C  C   . LYS C 1 61  ? 2.271   78.784  -65.933 1.00 37.68  ? 61  LYS D C   1 
ATOM   5201  O  O   . LYS C 1 61  ? 1.626   79.697  -65.413 1.00 35.10  ? 61  LYS D O   1 
ATOM   5202  C  CB  . LYS C 1 61  ? 2.056   76.591  -64.791 1.00 37.73  ? 61  LYS D CB  1 
ATOM   5203  C  CG  . LYS C 1 61  ? 2.551   75.573  -63.767 1.00 34.61  ? 61  LYS D CG  1 
ATOM   5204  C  CD  . LYS C 1 61  ? 3.571   74.595  -64.319 1.00 35.51  ? 61  LYS D CD  1 
ATOM   5205  C  CE  . LYS C 1 61  ? 4.059   73.679  -63.198 1.00 33.59  ? 61  LYS D CE  1 
ATOM   5206  N  NZ  . LYS C 1 61  ? 5.315   72.965  -63.506 1.00 30.59  ? 61  LYS D NZ  1 
ATOM   5207  N  N   . SER C 1 62  ? 2.316   78.593  -67.241 1.00 37.53  ? 62  SER D N   1 
ATOM   5208  C  CA  . SER C 1 62  ? 1.477   79.355  -68.152 1.00 36.43  ? 62  SER D CA  1 
ATOM   5209  C  C   . SER C 1 62  ? 0.505   78.397  -68.836 1.00 34.13  ? 62  SER D C   1 
ATOM   5210  O  O   . SER C 1 62  ? 0.604   77.172  -68.701 1.00 30.48  ? 62  SER D O   1 
ATOM   5211  C  CB  . SER C 1 62  ? 2.315   80.134  -69.181 1.00 36.92  ? 62  SER D CB  1 
ATOM   5212  O  OG  . SER C 1 62  ? 3.144   81.112  -68.561 1.00 37.68  ? 62  SER D OG  1 
ATOM   5213  N  N   . ASN C 1 63  ? -0.463  78.979  -69.545 1.00 30.99  ? 63  ASN D N   1 
ATOM   5214  C  CA  . ASN C 1 63  ? -1.450  78.187  -70.270 1.00 29.61  ? 63  ASN D CA  1 
ATOM   5215  C  C   . ASN C 1 63  ? -0.798  77.132  -71.165 1.00 31.49  ? 63  ASN D C   1 
ATOM   5216  O  O   . ASN C 1 63  ? -1.305  76.002  -71.281 1.00 31.93  ? 63  ASN D O   1 
ATOM   5217  C  CB  . ASN C 1 63  ? -2.352  79.106  -71.097 1.00 31.77  ? 63  ASN D CB  1 
ATOM   5218  C  CG  . ASN C 1 63  ? -3.314  79.933  -70.247 1.00 30.09  ? 63  ASN D CG  1 
ATOM   5219  O  OD1 . ASN C 1 63  ? -3.705  79.550  -69.134 1.00 29.04  ? 63  ASN D OD1 1 
ATOM   5220  N  ND2 . ASN C 1 63  ? -3.704  81.075  -70.780 1.00 31.10  ? 63  ASN D ND2 1 
ATOM   5221  N  N   . HIS C 1 64  ? 0.324   77.473  -71.809 1.00 27.73  ? 64  HIS D N   1 
ATOM   5222  C  CA  . HIS C 1 64  ? 0.940   76.542  -72.750 1.00 30.53  ? 64  HIS D CA  1 
ATOM   5223  C  C   . HIS C 1 64  ? 1.669   75.391  -72.058 1.00 33.08  ? 64  HIS D C   1 
ATOM   5224  O  O   . HIS C 1 64  ? 2.123   74.469  -72.744 1.00 35.48  ? 64  HIS D O   1 
ATOM   5225  C  CB  . HIS C 1 64  ? 1.879   77.296  -73.707 1.00 31.23  ? 64  HIS D CB  1 
ATOM   5226  C  CG  . HIS C 1 64  ? 3.151   77.779  -73.075 1.00 37.05  ? 64  HIS D CG  1 
ATOM   5227  N  ND1 . HIS C 1 64  ? 3.268   79.027  -72.498 1.00 35.65  ? 64  HIS D ND1 1 
ATOM   5228  C  CD2 . HIS C 1 64  ? 4.362   77.185  -72.937 1.00 33.68  ? 64  HIS D CD2 1 
ATOM   5229  C  CE1 . HIS C 1 64  ? 4.490   79.171  -72.015 1.00 38.13  ? 64  HIS D CE1 1 
ATOM   5230  N  NE2 . HIS C 1 64  ? 5.173   78.067  -72.267 1.00 35.77  ? 64  HIS D NE2 1 
ATOM   5231  N  N   . ASN C 1 65  ? 1.770   75.414  -70.721 1.00 32.67  ? 65  ASN D N   1 
ATOM   5232  C  CA  . ASN C 1 65  ? 2.318   74.319  -69.928 1.00 28.78  ? 65  ASN D CA  1 
ATOM   5233  C  C   . ASN C 1 65  ? 1.307   73.202  -69.666 1.00 30.06  ? 65  ASN D C   1 
ATOM   5234  O  O   . ASN C 1 65  ? 1.692   72.123  -69.198 1.00 28.62  ? 65  ASN D O   1 
ATOM   5235  C  CB  . ASN C 1 65  ? 2.852   74.876  -68.601 1.00 30.56  ? 65  ASN D CB  1 
ATOM   5236  C  CG  . ASN C 1 65  ? 4.028   75.836  -68.791 1.00 40.62  ? 65  ASN D CG  1 
ATOM   5237  O  OD1 . ASN C 1 65  ? 4.083   76.900  -68.167 1.00 44.34  ? 65  ASN D OD1 1 
ATOM   5238  N  ND2 . ASN C 1 65  ? 4.995   75.444  -69.624 1.00 40.51  ? 65  ASN D ND2 1 
ATOM   5239  N  N   . PHE C 1 66  ? 0.025   73.441  -69.908 1.00 29.05  ? 66  PHE D N   1 
ATOM   5240  C  CA  . PHE C 1 66  ? -1.017  72.435  -69.724 1.00 27.43  ? 66  PHE D CA  1 
ATOM   5241  C  C   . PHE C 1 66  ? -1.342  71.860  -71.094 1.00 27.10  ? 66  PHE D C   1 
ATOM   5242  O  O   . PHE C 1 66  ? -2.017  72.498  -71.904 1.00 28.95  ? 66  PHE D O   1 
ATOM   5243  C  CB  . PHE C 1 66  ? -2.248  73.041  -69.060 1.00 28.90  ? 66  PHE D CB  1 
ATOM   5244  C  CG  . PHE C 1 66  ? -1.986  73.585  -67.687 1.00 26.24  ? 66  PHE D CG  1 
ATOM   5245  C  CD1 . PHE C 1 66  ? -1.830  72.736  -66.616 1.00 21.16  ? 66  PHE D CD1 1 
ATOM   5246  C  CD2 . PHE C 1 66  ? -1.876  74.944  -67.479 1.00 28.39  ? 66  PHE D CD2 1 
ATOM   5247  C  CE1 . PHE C 1 66  ? -1.577  73.234  -65.366 1.00 26.25  ? 66  PHE D CE1 1 
ATOM   5248  C  CE2 . PHE C 1 66  ? -1.630  75.449  -66.218 1.00 26.63  ? 66  PHE D CE2 1 
ATOM   5249  C  CZ  . PHE C 1 66  ? -1.482  74.602  -65.166 1.00 25.87  ? 66  PHE D CZ  1 
ATOM   5250  N  N   . LEU C 1 67  ? -0.856  70.652  -71.350 1.00 31.08  ? 67  LEU D N   1 
ATOM   5251  C  CA  . LEU C 1 67  ? -1.124  69.952  -72.601 1.00 32.39  ? 67  LEU D CA  1 
ATOM   5252  C  C   . LEU C 1 67  ? -2.434  69.209  -72.418 1.00 27.62  ? 67  LEU D C   1 
ATOM   5253  O  O   . LEU C 1 67  ? -2.521  68.318  -71.574 1.00 31.48  ? 67  LEU D O   1 
ATOM   5254  C  CB  . LEU C 1 67  ? 0.010   68.984  -72.917 1.00 28.79  ? 67  LEU D CB  1 
ATOM   5255  C  CG  . LEU C 1 67  ? 1.413   69.513  -72.656 1.00 32.17  ? 67  LEU D CG  1 
ATOM   5256  C  CD1 . LEU C 1 67  ? 2.416   68.401  -72.831 1.00 35.72  ? 67  LEU D CD1 1 
ATOM   5257  C  CD2 . LEU C 1 67  ? 1.751   70.687  -73.578 1.00 37.13  ? 67  LEU D CD2 1 
ATOM   5258  N  N   . VAL C 1 68  ? -3.467  69.599  -73.154 1.00 29.28  ? 68  VAL D N   1 
ATOM   5259  C  CA  . VAL C 1 68  ? -4.761  68.931  -73.075 1.00 29.60  ? 68  VAL D CA  1 
ATOM   5260  C  C   . VAL C 1 68  ? -5.025  68.246  -74.407 1.00 29.23  ? 68  VAL D C   1 
ATOM   5261  O  O   . VAL C 1 68  ? -4.838  68.847  -75.470 1.00 24.16  ? 68  VAL D O   1 
ATOM   5262  C  CB  . VAL C 1 68  ? -5.892  69.905  -72.706 1.00 23.43  ? 68  VAL D CB  1 
ATOM   5263  C  CG1 . VAL C 1 68  ? -7.219  69.172  -72.642 1.00 15.28  ? 68  VAL D CG1 1 
ATOM   5264  C  CG2 . VAL C 1 68  ? -5.589  70.572  -71.377 1.00 22.96  ? 68  VAL D CG2 1 
ATOM   5265  N  N   . GLN C 1 69  ? -5.450  66.979  -74.342 1.00 31.31  ? 69  GLN D N   1 
ATOM   5266  C  CA  . GLN C 1 69  ? -5.630  66.141  -75.524 1.00 30.16  ? 69  GLN D CA  1 
ATOM   5267  C  C   . GLN C 1 69  ? -6.919  65.341  -75.402 1.00 27.10  ? 69  GLN D C   1 
ATOM   5268  O  O   . GLN C 1 69  ? -7.051  64.499  -74.508 1.00 27.37  ? 69  GLN D O   1 
ATOM   5269  C  CB  . GLN C 1 69  ? -4.436  65.202  -75.701 1.00 32.12  ? 69  GLN D CB  1 
ATOM   5270  C  CG  . GLN C 1 69  ? -4.373  64.513  -77.047 1.00 34.95  ? 69  GLN D CG  1 
ATOM   5271  C  CD  . GLN C 1 69  ? -3.097  63.724  -77.225 1.00 41.13  ? 69  GLN D CD  1 
ATOM   5272  O  OE1 . GLN C 1 69  ? -2.042  64.096  -76.703 1.00 41.89  ? 69  GLN D OE1 1 
ATOM   5273  N  NE2 . GLN C 1 69  ? -3.187  62.610  -77.956 1.00 42.36  ? 69  GLN D NE2 1 
ATOM   5274  N  N   . ALA C 1 70  ? -7.869  65.609  -76.289 1.00 27.21  ? 70  ALA D N   1 
ATOM   5275  C  CA  . ALA C 1 70  ? -9.098  64.829  -76.411 1.00 26.21  ? 70  ALA D CA  1 
ATOM   5276  C  C   . ALA C 1 70  ? -8.893  63.804  -77.526 1.00 28.87  ? 70  ALA D C   1 
ATOM   5277  O  O   . ALA C 1 70  ? -8.747  64.172  -78.695 1.00 23.46  ? 70  ALA D O   1 
ATOM   5278  C  CB  . ALA C 1 70  ? -10.299 65.729  -76.692 1.00 25.97  ? 70  ALA D CB  1 
ATOM   5279  N  N   . GLY C 1 71  ? -8.808  62.529  -77.155 1.00 28.73  ? 71  GLY D N   1 
ATOM   5280  C  CA  . GLY C 1 71  ? -8.415  61.512  -78.103 1.00 29.64  ? 71  GLY D CA  1 
ATOM   5281  C  C   . GLY C 1 71  ? -7.057  61.844  -78.690 1.00 34.78  ? 71  GLY D C   1 
ATOM   5282  O  O   . GLY C 1 71  ? -6.052  61.904  -77.975 1.00 28.64  ? 71  GLY D O   1 
ATOM   5283  N  N   . ASN C 1 72  ? -7.022  62.119  -79.990 1.00 35.85  ? 72  ASN D N   1 
ATOM   5284  C  CA  . ASN C 1 72  ? -5.777  62.428  -80.671 1.00 35.74  ? 72  ASN D CA  1 
ATOM   5285  C  C   . ASN C 1 72  ? -5.612  63.916  -80.966 1.00 38.34  ? 72  ASN D C   1 
ATOM   5286  O  O   . ASN C 1 72  ? -4.543  64.306  -81.429 1.00 44.14  ? 72  ASN D O   1 
ATOM   5287  C  CB  . ASN C 1 72  ? -5.689  61.619  -81.975 1.00 33.55  ? 72  ASN D CB  1 
ATOM   5288  C  CG  . ASN C 1 72  ? -4.252  61.304  -82.385 1.00 43.47  ? 72  ASN D CG  1 
ATOM   5289  O  OD1 . ASN C 1 72  ? -3.838  61.599  -83.508 1.00 41.70  ? 72  ASN D OD1 1 
ATOM   5290  N  ND2 . ASN C 1 72  ? -3.485  60.701  -81.473 1.00 44.08  ? 72  ASN D ND2 1 
ATOM   5291  N  N   . VAL C 1 73  ? -6.616  64.761  -80.674 1.00 35.80  ? 73  VAL D N   1 
ATOM   5292  C  CA  . VAL C 1 73  ? -6.583  66.181  -81.027 1.00 35.89  ? 73  VAL D CA  1 
ATOM   5293  C  C   . VAL C 1 73  ? -6.149  67.008  -79.820 1.00 33.87  ? 73  VAL D C   1 
ATOM   5294  O  O   . VAL C 1 73  ? -6.666  66.838  -78.708 1.00 33.48  ? 73  VAL D O   1 
ATOM   5295  C  CB  . VAL C 1 73  ? -7.947  66.671  -81.561 1.00 37.87  ? 73  VAL D CB  1 
ATOM   5296  C  CG1 . VAL C 1 73  ? -9.052  66.421  -80.561 1.00 36.53  ? 73  VAL D CG1 1 
ATOM   5297  C  CG2 . VAL C 1 73  ? -7.908  68.179  -81.917 1.00 27.16  ? 73  VAL D CG2 1 
ATOM   5298  N  N   . GLN C 1 74  ? -5.230  67.935  -80.049 1.00 36.61  ? 74  GLN D N   1 
ATOM   5299  C  CA  . GLN C 1 74  ? -4.751  68.830  -79.006 1.00 34.76  ? 74  GLN D CA  1 
ATOM   5300  C  C   . GLN C 1 74  ? -5.724  69.993  -78.811 1.00 32.82  ? 74  GLN D C   1 
ATOM   5301  O  O   . GLN C 1 74  ? -6.117  70.644  -79.780 1.00 42.94  ? 74  GLN D O   1 
ATOM   5302  C  CB  . GLN C 1 74  ? -3.378  69.351  -79.405 1.00 37.71  ? 74  GLN D CB  1 
ATOM   5303  C  CG  . GLN C 1 74  ? -2.557  69.946  -78.285 1.00 45.65  ? 74  GLN D CG  1 
ATOM   5304  C  CD  . GLN C 1 74  ? -2.079  68.882  -77.302 1.00 38.03  ? 74  GLN D CD  1 
ATOM   5305  O  OE1 . GLN C 1 74  ? -1.913  67.715  -77.664 1.00 32.05  ? 74  GLN D OE1 1 
ATOM   5306  N  NE2 . GLN C 1 74  ? -1.784  69.301  -76.079 1.00 35.79  ? 74  GLN D NE2 1 
ATOM   5307  N  N   . LEU C 1 75  ? -6.120  70.257  -77.570 1.00 34.02  ? 75  LEU D N   1 
ATOM   5308  C  CA  . LEU C 1 75  ? -6.928  71.432  -77.270 1.00 30.10  ? 75  LEU D CA  1 
ATOM   5309  C  C   . LEU C 1 75  ? -6.028  72.592  -76.872 1.00 33.39  ? 75  LEU D C   1 
ATOM   5310  O  O   . LEU C 1 75  ? -4.934  72.402  -76.331 1.00 37.61  ? 75  LEU D O   1 
ATOM   5311  C  CB  . LEU C 1 75  ? -7.900  71.172  -76.117 1.00 26.30  ? 75  LEU D CB  1 
ATOM   5312  C  CG  . LEU C 1 75  ? -8.826  69.966  -76.068 1.00 26.57  ? 75  LEU D CG  1 
ATOM   5313  C  CD1 . LEU C 1 75  ? -9.769  70.162  -74.900 1.00 27.82  ? 75  LEU D CD1 1 
ATOM   5314  C  CD2 . LEU C 1 75  ? -9.591  69.806  -77.359 1.00 30.86  ? 75  LEU D CD2 1 
ATOM   5315  N  N   . ARG C 1 76  ? -6.532  73.805  -77.068 1.00 29.32  ? 76  ARG D N   1 
ATOM   5316  C  CA  . ARG C 1 76  ? -5.750  75.012  -76.840 1.00 33.04  ? 76  ARG D CA  1 
ATOM   5317  C  C   . ARG C 1 76  ? -6.257  75.682  -75.567 1.00 30.22  ? 76  ARG D C   1 
ATOM   5318  O  O   . ARG C 1 76  ? -7.436  76.035  -75.480 1.00 28.14  ? 76  ARG D O   1 
ATOM   5319  C  CB  . ARG C 1 76  ? -5.834  75.964  -78.040 1.00 39.18  ? 76  ARG D CB  1 
ATOM   5320  C  CG  . ARG C 1 76  ? -4.896  77.160  -77.952 1.00 38.05  ? 76  ARG D CG  1 
ATOM   5321  C  CD  . ARG C 1 76  ? -4.965  78.065  -79.188 1.00 45.52  ? 76  ARG D CD  1 
ATOM   5322  N  NE  . ARG C 1 76  ? -4.613  77.396  -80.438 1.00 47.57  ? 76  ARG D NE  1 
ATOM   5323  C  CZ  . ARG C 1 76  ? -3.384  77.310  -80.937 1.00 39.68  ? 76  ARG D CZ  1 
ATOM   5324  N  NH1 . ARG C 1 76  ? -2.347  77.837  -80.311 1.00 37.08  ? 76  ARG D NH1 1 
ATOM   5325  N  NH2 . ARG C 1 76  ? -3.196  76.694  -82.105 1.00 36.41  ? 76  ARG D NH2 1 
ATOM   5326  N  N   . VAL C 1 77  ? -5.367  75.836  -74.587 1.00 27.94  ? 77  VAL D N   1 
ATOM   5327  C  CA  . VAL C 1 77  ? -5.699  76.378  -73.269 1.00 31.15  ? 77  VAL D CA  1 
ATOM   5328  C  C   . VAL C 1 77  ? -5.550  77.900  -73.284 1.00 30.73  ? 77  VAL D C   1 
ATOM   5329  O  O   . VAL C 1 77  ? -4.470  78.421  -73.571 1.00 31.74  ? 77  VAL D O   1 
ATOM   5330  C  CB  . VAL C 1 77  ? -4.815  75.752  -72.178 1.00 29.80  ? 77  VAL D CB  1 
ATOM   5331  C  CG1 . VAL C 1 77  ? -5.063  76.425  -70.830 1.00 23.73  ? 77  VAL D CG1 1 
ATOM   5332  C  CG2 . VAL C 1 77  ? -5.073  74.241  -72.082 1.00 24.98  ? 77  VAL D CG2 1 
ATOM   5333  N  N   . ILE C 1 78  ? -6.624  78.617  -72.952 1.00 27.75  ? 78  ILE D N   1 
ATOM   5334  C  CA  . ILE C 1 78  ? -6.620  80.076  -72.995 1.00 32.03  ? 78  ILE D CA  1 
ATOM   5335  C  C   . ILE C 1 78  ? -6.722  80.701  -71.613 1.00 36.25  ? 78  ILE D C   1 
ATOM   5336  O  O   . ILE C 1 78  ? -6.724  81.936  -71.497 1.00 31.37  ? 78  ILE D O   1 
ATOM   5337  C  CB  . ILE C 1 78  ? -7.750  80.605  -73.895 1.00 30.52  ? 78  ILE D CB  1 
ATOM   5338  C  CG1 . ILE C 1 78  ? -9.112  80.196  -73.327 1.00 34.37  ? 78  ILE D CG1 1 
ATOM   5339  C  CG2 . ILE C 1 78  ? -7.596  80.090  -75.313 1.00 31.45  ? 78  ILE D CG2 1 
ATOM   5340  C  CD1 . ILE C 1 78  ? -10.295 80.725  -74.140 1.00 33.91  ? 78  ILE D CD1 1 
ATOM   5341  N  N   . GLY C 1 79  ? -6.828  79.895  -70.565 1.00 34.46  ? 79  GLY D N   1 
ATOM   5342  C  CA  . GLY C 1 79  ? -6.812  80.409  -69.215 1.00 26.13  ? 79  GLY D CA  1 
ATOM   5343  C  C   . GLY C 1 79  ? -6.790  79.262  -68.237 1.00 28.92  ? 79  GLY D C   1 
ATOM   5344  O  O   . GLY C 1 79  ? -7.178  78.135  -68.563 1.00 28.53  ? 79  GLY D O   1 
ATOM   5345  N  N   . HIS C 1 80  ? -6.367  79.568  -67.017 1.00 28.84  ? 80  HIS D N   1 
ATOM   5346  C  CA  . HIS C 1 80  ? -6.323  78.542  -65.990 1.00 31.94  ? 80  HIS D CA  1 
ATOM   5347  C  C   . HIS C 1 80  ? -6.549  79.193  -64.640 1.00 28.03  ? 80  HIS D C   1 
ATOM   5348  O  O   . HIS C 1 80  ? -6.217  80.360  -64.432 1.00 26.43  ? 80  HIS D O   1 
ATOM   5349  C  CB  . HIS C 1 80  ? -4.990  77.771  -66.011 1.00 23.46  ? 80  HIS D CB  1 
ATOM   5350  C  CG  . HIS C 1 80  ? -3.801  78.584  -65.599 1.00 26.03  ? 80  HIS D CG  1 
ATOM   5351  N  ND1 . HIS C 1 80  ? -3.054  79.326  -66.495 1.00 30.41  ? 80  HIS D ND1 1 
ATOM   5352  C  CD2 . HIS C 1 80  ? -3.212  78.754  -64.390 1.00 27.94  ? 80  HIS D CD2 1 
ATOM   5353  C  CE1 . HIS C 1 80  ? -2.064  79.923  -65.854 1.00 24.14  ? 80  HIS D CE1 1 
ATOM   5354  N  NE2 . HIS C 1 80  ? -2.132  79.588  -64.577 1.00 30.95  ? 80  HIS D NE2 1 
ATOM   5355  N  N   . SER C 1 81  ? -7.135  78.423  -63.733 1.00 25.58  ? 81  SER D N   1 
ATOM   5356  C  CA  . SER C 1 81  ? -7.328  78.862  -62.362 1.00 30.59  ? 81  SER D CA  1 
ATOM   5357  C  C   . SER C 1 81  ? -7.493  77.644  -61.469 1.00 37.61  ? 81  SER D C   1 
ATOM   5358  O  O   . SER C 1 81  ? -7.766  76.531  -61.932 1.00 30.29  ? 81  SER D O   1 
ATOM   5359  C  CB  . SER C 1 81  ? -8.549  79.757  -62.217 1.00 26.99  ? 81  SER D CB  1 
ATOM   5360  O  OG  . SER C 1 81  ? -9.698  79.066  -62.647 1.00 34.21  ? 81  SER D OG  1 
ATOM   5361  N  N   . MET C 1 82  ? -7.365  77.890  -60.171 1.00 36.70  ? 82  MET D N   1 
ATOM   5362  C  CA  . MET C 1 82  ? -7.449  76.859  -59.157 1.00 32.76  ? 82  MET D CA  1 
ATOM   5363  C  C   . MET C 1 82  ? -8.666  77.113  -58.283 1.00 34.22  ? 82  MET D C   1 
ATOM   5364  O  O   . MET C 1 82  ? -8.906  78.246  -57.859 1.00 35.71  ? 82  MET D O   1 
ATOM   5365  C  CB  . MET C 1 82  ? -6.176  76.841  -58.323 1.00 33.19  ? 82  MET D CB  1 
ATOM   5366  C  CG  . MET C 1 82  ? -6.167  75.791  -57.266 1.00 33.27  ? 82  MET D CG  1 
ATOM   5367  S  SD  . MET C 1 82  ? -4.498  75.531  -56.707 1.00 37.49  ? 82  MET D SD  1 
ATOM   5368  C  CE  . MET C 1 82  ? -4.116  77.102  -55.934 1.00 39.36  ? 82  MET D CE  1 
ATOM   5369  N  N   . GLN C 1 83  ? -9.450  76.071  -58.052 1.00 36.59  ? 83  GLN D N   1 
ATOM   5370  C  CA  . GLN C 1 83  ? -10.574 76.108  -57.124 1.00 38.63  ? 83  GLN D CA  1 
ATOM   5371  C  C   . GLN C 1 83  ? -10.424 74.927  -56.184 1.00 33.17  ? 83  GLN D C   1 
ATOM   5372  O  O   . GLN C 1 83  ? -10.609 73.781  -56.602 1.00 32.26  ? 83  GLN D O   1 
ATOM   5373  C  CB  . GLN C 1 83  ? -11.917 76.055  -57.844 1.00 40.80  ? 83  GLN D CB  1 
ATOM   5374  C  CG  . GLN C 1 83  ? -13.084 75.808  -56.892 1.00 37.19  ? 83  GLN D CG  1 
ATOM   5375  C  CD  . GLN C 1 83  ? -14.436 75.995  -57.563 1.00 43.33  ? 83  GLN D CD  1 
ATOM   5376  O  OE1 . GLN C 1 83  ? -14.546 75.896  -58.782 1.00 46.68  ? 83  GLN D OE1 1 
ATOM   5377  N  NE2 . GLN C 1 83  ? -15.480 76.235  -56.761 1.00 45.69  ? 83  GLN D NE2 1 
ATOM   5378  N  N   . ASN C 1 84  ? -10.079 75.213  -54.926 1.00 33.73  ? 84  ASN D N   1 
ATOM   5379  C  CA  . ASN C 1 84  ? -9.783  74.195  -53.922 1.00 29.91  ? 84  ASN D CA  1 
ATOM   5380  C  C   . ASN C 1 84  ? -8.760  73.202  -54.457 1.00 32.18  ? 84  ASN D C   1 
ATOM   5381  O  O   . ASN C 1 84  ? -7.634  73.592  -54.787 1.00 25.81  ? 84  ASN D O   1 
ATOM   5382  C  CB  . ASN C 1 84  ? -11.080 73.519  -53.501 1.00 20.74  ? 84  ASN D CB  1 
ATOM   5383  C  CG  . ASN C 1 84  ? -12.080 74.523  -52.973 1.00 31.14  ? 84  ASN D CG  1 
ATOM   5384  O  OD1 . ASN C 1 84  ? -11.733 75.327  -52.106 1.00 32.69  ? 84  ASN D OD1 1 
ATOM   5385  N  ND2 . ASN C 1 84  ? -13.305 74.527  -53.518 1.00 24.51  ? 84  ASN D ND2 1 
ATOM   5386  N  N   . CYS C 1 85  ? -9.125  71.932  -54.578 1.00 24.07  ? 85  CYS D N   1 
ATOM   5387  C  CA  . CYS C 1 85  ? -8.143  70.955  -55.008 1.00 27.38  ? 85  CYS D CA  1 
ATOM   5388  C  C   . CYS C 1 85  ? -8.261  70.599  -56.481 1.00 27.26  ? 85  CYS D C   1 
ATOM   5389  O  O   . CYS C 1 85  ? -7.561  69.686  -56.936 1.00 25.78  ? 85  CYS D O   1 
ATOM   5390  C  CB  . CYS C 1 85  ? -8.219  69.699  -54.142 1.00 27.97  ? 85  CYS D CB  1 
ATOM   5391  S  SG  . CYS C 1 85  ? -7.782  70.041  -52.434 1.00 28.41  ? 85  CYS D SG  1 
ATOM   5392  N  N   . VAL C 1 86  ? -9.097  71.306  -57.248 1.00 26.42  ? 86  VAL D N   1 
ATOM   5393  C  CA  . VAL C 1 86  ? -9.196  71.028  -58.673 1.00 24.30  ? 86  VAL D CA  1 
ATOM   5394  C  C   . VAL C 1 86  ? -8.660  72.203  -59.464 1.00 31.81  ? 86  VAL D C   1 
ATOM   5395  O  O   . VAL C 1 86  ? -8.812  73.373  -59.095 1.00 31.96  ? 86  VAL D O   1 
ATOM   5396  C  CB  . VAL C 1 86  ? -10.624 70.659  -59.135 1.00 28.63  ? 86  VAL D CB  1 
ATOM   5397  C  CG1 . VAL C 1 86  ? -11.066 69.284  -58.519 1.00 26.66  ? 86  VAL D CG1 1 
ATOM   5398  C  CG2 . VAL C 1 86  ? -11.590 71.760  -58.788 1.00 29.89  ? 86  VAL D CG2 1 
ATOM   5399  N  N   . LEU C 1 87  ? -8.056  71.868  -60.595 1.00 28.26  ? 87  LEU D N   1 
ATOM   5400  C  CA  . LEU C 1 87  ? -7.583  72.838  -61.556 1.00 26.78  ? 87  LEU D CA  1 
ATOM   5401  C  C   . LEU C 1 87  ? -8.685  73.040  -62.582 1.00 26.28  ? 87  LEU D C   1 
ATOM   5402  O  O   . LEU C 1 87  ? -9.418  72.099  -62.898 1.00 29.35  ? 87  LEU D O   1 
ATOM   5403  C  CB  . LEU C 1 87  ? -6.322  72.313  -62.234 1.00 28.25  ? 87  LEU D CB  1 
ATOM   5404  C  CG  . LEU C 1 87  ? -5.257  73.253  -62.750 1.00 26.07  ? 87  LEU D CG  1 
ATOM   5405  C  CD1 . LEU C 1 87  ? -4.594  73.888  -61.565 1.00 27.62  ? 87  LEU D CD1 1 
ATOM   5406  C  CD2 . LEU C 1 87  ? -4.273  72.442  -63.531 1.00 30.92  ? 87  LEU D CD2 1 
ATOM   5407  N  N   . LYS C 1 88  ? -8.857  74.277  -63.042 1.00 20.76  ? 88  LYS D N   1 
ATOM   5408  C  CA  . LYS C 1 88  ? -9.827  74.585  -64.089 1.00 26.33  ? 88  LYS D CA  1 
ATOM   5409  C  C   . LYS C 1 88  ? -9.081  75.195  -65.268 1.00 28.23  ? 88  LYS D C   1 
ATOM   5410  O  O   . LYS C 1 88  ? -8.479  76.271  -65.144 1.00 30.59  ? 88  LYS D O   1 
ATOM   5411  C  CB  . LYS C 1 88  ? -10.956 75.492  -63.594 1.00 28.91  ? 88  LYS D CB  1 
ATOM   5412  C  CG  . LYS C 1 88  ? -11.794 74.833  -62.507 1.00 33.38  ? 88  LYS D CG  1 
ATOM   5413  C  CD  . LYS C 1 88  ? -13.193 75.425  -62.394 1.00 35.99  ? 88  LYS D CD  1 
ATOM   5414  C  CE  . LYS C 1 88  ? -13.248 76.710  -61.599 1.00 39.55  ? 88  LYS D CE  1 
ATOM   5415  N  NZ  . LYS C 1 88  ? -14.679 77.003  -61.271 1.00 42.84  ? 88  LYS D NZ  1 
ATOM   5416  N  N   . LEU C 1 89  ? -9.071  74.468  -66.388 1.00 22.75  ? 89  LEU D N   1 
ATOM   5417  C  CA  . LEU C 1 89  ? -8.378  74.869  -67.601 1.00 25.38  ? 89  LEU D CA  1 
ATOM   5418  C  C   . LEU C 1 89  ? -9.409  75.329  -68.627 1.00 27.89  ? 89  LEU D C   1 
ATOM   5419  O  O   . LEU C 1 89  ? -10.176 74.509  -69.160 1.00 24.80  ? 89  LEU D O   1 
ATOM   5420  C  CB  . LEU C 1 89  ? -7.528  73.719  -68.143 1.00 20.83  ? 89  LEU D CB  1 
ATOM   5421  C  CG  . LEU C 1 89  ? -6.530  73.037  -67.204 1.00 18.79  ? 89  LEU D CG  1 
ATOM   5422  C  CD1 . LEU C 1 89  ? -5.771  71.985  -67.971 1.00 20.79  ? 89  LEU D CD1 1 
ATOM   5423  C  CD2 . LEU C 1 89  ? -5.560  73.999  -66.599 1.00 18.44  ? 89  LEU D CD2 1 
ATOM   5424  N  N   . LYS C 1 90  ? -9.421  76.635  -68.914 1.00 28.63  ? 90  LYS D N   1 
ATOM   5425  C  CA  . LYS C 1 90  ? -10.275 77.152  -69.976 1.00 28.15  ? 90  LYS D CA  1 
ATOM   5426  C  C   . LYS C 1 90  ? -9.610  76.903  -71.324 1.00 29.62  ? 90  LYS D C   1 
ATOM   5427  O  O   . LYS C 1 90  ? -8.473  77.321  -71.555 1.00 30.49  ? 90  LYS D O   1 
ATOM   5428  C  CB  . LYS C 1 90  ? -10.568 78.633  -69.773 1.00 27.65  ? 90  LYS D CB  1 
ATOM   5429  C  CG  . LYS C 1 90  ? -11.607 79.206  -70.736 1.00 31.75  ? 90  LYS D CG  1 
ATOM   5430  C  CD  . LYS C 1 90  ? -12.091 80.575  -70.265 1.00 38.80  ? 90  LYS D CD  1 
ATOM   5431  C  CE  . LYS C 1 90  ? -13.217 81.162  -71.149 1.00 43.24  ? 90  LYS D CE  1 
ATOM   5432  N  NZ  . LYS C 1 90  ? -12.791 81.808  -72.448 1.00 37.46  ? 90  LYS D NZ  1 
ATOM   5433  N  N   . VAL C 1 91  ? -10.326 76.232  -72.214 1.00 28.51  ? 91  VAL D N   1 
ATOM   5434  C  CA  . VAL C 1 91  ? -9.846  75.961  -73.553 1.00 25.62  ? 91  VAL D CA  1 
ATOM   5435  C  C   . VAL C 1 91  ? -10.754 76.706  -74.517 1.00 30.47  ? 91  VAL D C   1 
ATOM   5436  O  O   . VAL C 1 91  ? -11.866 77.113  -74.171 1.00 32.03  ? 91  VAL D O   1 
ATOM   5437  C  CB  . VAL C 1 91  ? -9.824  74.457  -73.858 1.00 29.38  ? 91  VAL D CB  1 
ATOM   5438  C  CG1 . VAL C 1 91  ? -8.790  73.767  -72.999 1.00 26.16  ? 91  VAL D CG1 1 
ATOM   5439  C  CG2 . VAL C 1 91  ? -11.188 73.870  -73.579 1.00 27.39  ? 91  VAL D CG2 1 
ATOM   5440  N  N   . ASP C 1 92  ? -10.278 76.880  -75.745 1.00 31.47  ? 92  ASP D N   1 
ATOM   5441  C  CA  . ASP C 1 92  ? -11.007 77.737  -76.671 1.00 34.56  ? 92  ASP D CA  1 
ATOM   5442  C  C   . ASP C 1 92  ? -12.178 77.036  -77.334 1.00 31.83  ? 92  ASP D C   1 
ATOM   5443  O  O   . ASP C 1 92  ? -12.892 77.668  -78.121 1.00 37.52  ? 92  ASP D O   1 
ATOM   5444  C  CB  . ASP C 1 92  ? -10.066 78.262  -77.750 1.00 34.02  ? 92  ASP D CB  1 
ATOM   5445  C  CG  . ASP C 1 92  ? -9.537  77.156  -78.644 1.00 39.07  ? 92  ASP D CG  1 
ATOM   5446  O  OD1 . ASP C 1 92  ? -9.807  75.945  -78.368 1.00 40.17  ? 92  ASP D OD1 1 
ATOM   5447  O  OD2 . ASP C 1 92  ? -8.846  77.507  -79.626 1.00 39.63  ? 92  ASP D OD2 1 
ATOM   5448  N  N   . THR C 1 93  ? -12.397 75.765  -77.035 1.00 29.01  ? 93  THR D N   1 
ATOM   5449  C  CA  . THR C 1 93  ? -13.441 74.982  -77.678 1.00 33.45  ? 93  THR D CA  1 
ATOM   5450  C  C   . THR C 1 93  ? -14.372 74.386  -76.633 1.00 33.28  ? 93  THR D C   1 
ATOM   5451  O  O   . THR C 1 93  ? -13.916 73.709  -75.707 1.00 27.10  ? 93  THR D O   1 
ATOM   5452  C  CB  . THR C 1 93  ? -12.839 73.861  -78.520 1.00 34.27  ? 93  THR D CB  1 
ATOM   5453  O  OG1 . THR C 1 93  ? -11.888 74.413  -79.442 1.00 33.21  ? 93  THR D OG1 1 
ATOM   5454  C  CG2 . THR C 1 93  ? -13.935 73.152  -79.278 1.00 28.71  ? 93  THR D CG2 1 
ATOM   5455  N  N   . ALA C 1 94  ? -15.672 74.634  -76.794 1.00 32.58  ? 94  ALA D N   1 
ATOM   5456  C  CA  . ALA C 1 94  ? -16.681 73.955  -75.995 1.00 27.62  ? 94  ALA D CA  1 
ATOM   5457  C  C   . ALA C 1 94  ? -16.826 72.508  -76.464 1.00 28.22  ? 94  ALA D C   1 
ATOM   5458  O  O   . ALA C 1 94  ? -16.907 72.243  -77.668 1.00 23.29  ? 94  ALA D O   1 
ATOM   5459  C  CB  . ALA C 1 94  ? -18.021 74.688  -76.099 1.00 29.94  ? 94  ALA D CB  1 
ATOM   5460  N  N   . ASN C 1 95  ? -16.883 71.574  -75.505 1.00 29.17  ? 95  ASN D N   1 
ATOM   5461  C  CA  . ASN C 1 95  ? -17.000 70.148  -75.808 1.00 24.65  ? 95  ASN D CA  1 
ATOM   5462  C  C   . ASN C 1 95  ? -18.315 69.895  -76.521 1.00 25.48  ? 95  ASN D C   1 
ATOM   5463  O  O   . ASN C 1 95  ? -19.380 70.159  -75.949 1.00 26.94  ? 95  ASN D O   1 
ATOM   5464  C  CB  . ASN C 1 95  ? -16.916 69.289  -74.531 1.00 25.67  ? 95  ASN D CB  1 
ATOM   5465  C  CG  . ASN C 1 95  ? -16.984 67.771  -74.803 1.00 23.29  ? 95  ASN D CG  1 
ATOM   5466  O  OD1 . ASN C 1 95  ? -17.069 67.318  -75.951 1.00 19.41  ? 95  ASN D OD1 1 
ATOM   5467  N  ND2 . ASN C 1 95  ? -16.920 66.980  -73.724 1.00 25.88  ? 95  ASN D ND2 1 
ATOM   5468  N  N   . PRO C 1 96  ? -18.291 69.457  -77.778 1.00 26.01  ? 96  PRO D N   1 
ATOM   5469  C  CA  . PRO C 1 96  ? -19.555 69.162  -78.466 1.00 25.04  ? 96  PRO D CA  1 
ATOM   5470  C  C   . PRO C 1 96  ? -20.331 68.025  -77.827 1.00 24.55  ? 96  PRO D C   1 
ATOM   5471  O  O   . PRO C 1 96  ? -21.550 67.936  -78.022 1.00 25.05  ? 96  PRO D O   1 
ATOM   5472  C  CB  . PRO C 1 96  ? -19.103 68.816  -79.895 1.00 26.28  ? 96  PRO D CB  1 
ATOM   5473  C  CG  . PRO C 1 96  ? -17.646 68.373  -79.749 1.00 21.93  ? 96  PRO D CG  1 
ATOM   5474  C  CD  . PRO C 1 96  ? -17.104 69.185  -78.617 1.00 21.70  ? 96  PRO D CD  1 
ATOM   5475  N  N   . LYS C 1 97  ? -19.676 67.165  -77.059 1.00 21.89  ? 97  LYS D N   1 
ATOM   5476  C  CA  . LYS C 1 97  ? -20.351 66.041  -76.434 1.00 25.96  ? 97  LYS D CA  1 
ATOM   5477  C  C   . LYS C 1 97  ? -20.796 66.333  -75.010 1.00 23.65  ? 97  LYS D C   1 
ATOM   5478  O  O   . LYS C 1 97  ? -21.254 65.417  -74.326 1.00 24.53  ? 97  LYS D O   1 
ATOM   5479  C  CB  . LYS C 1 97  ? -19.441 64.806  -76.450 1.00 25.74  ? 97  LYS D CB  1 
ATOM   5480  C  CG  . LYS C 1 97  ? -19.128 64.257  -77.851 1.00 25.73  ? 97  LYS D CG  1 
ATOM   5481  C  CD  . LYS C 1 97  ? -18.314 62.998  -77.733 1.00 23.10  ? 97  LYS D CD  1 
ATOM   5482  C  CE  . LYS C 1 97  ? -17.520 62.675  -78.978 1.00 24.71  ? 97  LYS D CE  1 
ATOM   5483  N  NZ  . LYS C 1 97  ? -16.553 61.551  -78.653 1.00 27.86  ? 97  LYS D NZ  1 
ATOM   5484  N  N   . THR C 1 98  ? -20.707 67.580  -74.558 1.00 25.94  ? 98  THR D N   1 
ATOM   5485  C  CA  . THR C 1 98  ? -21.094 67.904  -73.188 1.00 24.88  ? 98  THR D CA  1 
ATOM   5486  C  C   . THR C 1 98  ? -22.532 67.481  -72.909 1.00 26.22  ? 98  THR D C   1 
ATOM   5487  O  O   . THR C 1 98  ? -23.448 67.951  -73.601 1.00 26.44  ? 98  THR D O   1 
ATOM   5488  C  CB  . THR C 1 98  ? -20.978 69.399  -72.919 1.00 25.98  ? 98  THR D CB  1 
ATOM   5489  O  OG1 . THR C 1 98  ? -19.642 69.832  -73.175 1.00 30.14  ? 98  THR D OG1 1 
ATOM   5490  C  CG2 . THR C 1 98  ? -21.312 69.675  -71.481 1.00 24.67  ? 98  THR D CG2 1 
ATOM   5491  N  N   . PRO C 1 99  ? -22.780 66.634  -71.906 1.00 25.48  ? 99  PRO D N   1 
ATOM   5492  C  CA  . PRO C 1 99  ? -24.159 66.311  -71.516 1.00 22.28  ? 99  PRO D CA  1 
ATOM   5493  C  C   . PRO C 1 99  ? -24.733 67.389  -70.613 1.00 20.93  ? 99  PRO D C   1 
ATOM   5494  O  O   . PRO C 1 99  ? -24.012 68.244  -70.104 1.00 27.43  ? 99  PRO D O   1 
ATOM   5495  C  CB  . PRO C 1 99  ? -23.999 64.992  -70.752 1.00 25.91  ? 99  PRO D CB  1 
ATOM   5496  C  CG  . PRO C 1 99  ? -22.650 65.146  -70.072 1.00 24.02  ? 99  PRO D CG  1 
ATOM   5497  C  CD  . PRO C 1 99  ? -21.789 65.952  -71.051 1.00 21.72  ? 99  PRO D CD  1 
ATOM   5498  N  N   . LYS C 1 100 ? -26.054 67.336  -70.417 1.00 31.04  ? 100 LYS D N   1 
ATOM   5499  C  CA  . LYS C 1 100 ? -26.652 68.045  -69.286 1.00 33.02  ? 100 LYS D CA  1 
ATOM   5500  C  C   . LYS C 1 100 ? -26.077 67.470  -67.999 1.00 32.39  ? 100 LYS D C   1 
ATOM   5501  O  O   . LYS C 1 100 ? -26.017 66.245  -67.828 1.00 29.48  ? 100 LYS D O   1 
ATOM   5502  C  CB  . LYS C 1 100 ? -28.183 67.940  -69.294 1.00 34.22  ? 100 LYS D CB  1 
ATOM   5503  C  CG  . LYS C 1 100 ? -28.794 68.163  -70.660 1.00 42.20  ? 100 LYS D CG  1 
ATOM   5504  C  CD  . LYS C 1 100 ? -30.328 68.252  -70.668 1.00 57.10  ? 100 LYS D CD  1 
ATOM   5505  C  CE  . LYS C 1 100 ? -30.837 68.650  -72.094 1.00 56.21  ? 100 LYS D CE  1 
ATOM   5506  N  NZ  . LYS C 1 100 ? -32.310 68.938  -72.183 1.00 42.50  ? 100 LYS D NZ  1 
ATOM   5507  N  N   . TYR C 1 101 ? -25.651 68.352  -67.093 1.00 27.45  ? 101 TYR D N   1 
ATOM   5508  C  CA  . TYR C 1 101 ? -24.870 67.880  -65.966 1.00 27.05  ? 101 TYR D CA  1 
ATOM   5509  C  C   . TYR C 1 101 ? -25.030 68.789  -64.758 1.00 30.49  ? 101 TYR D C   1 
ATOM   5510  O  O   . TYR C 1 101 ? -25.411 69.955  -64.870 1.00 29.46  ? 101 TYR D O   1 
ATOM   5511  C  CB  . TYR C 1 101 ? -23.391 67.770  -66.333 1.00 27.42  ? 101 TYR D CB  1 
ATOM   5512  C  CG  . TYR C 1 101 ? -22.655 69.087  -66.442 1.00 25.54  ? 101 TYR D CG  1 
ATOM   5513  C  CD1 . TYR C 1 101 ? -22.039 69.642  -65.334 1.00 22.71  ? 101 TYR D CD1 1 
ATOM   5514  C  CD2 . TYR C 1 101 ? -22.551 69.759  -67.659 1.00 25.73  ? 101 TYR D CD2 1 
ATOM   5515  C  CE1 . TYR C 1 101 ? -21.350 70.835  -65.421 1.00 25.22  ? 101 TYR D CE1 1 
ATOM   5516  C  CE2 . TYR C 1 101 ? -21.856 70.965  -67.759 1.00 20.84  ? 101 TYR D CE2 1 
ATOM   5517  C  CZ  . TYR C 1 101 ? -21.258 71.491  -66.633 1.00 25.19  ? 101 TYR D CZ  1 
ATOM   5518  O  OH  . TYR C 1 101 ? -20.551 72.678  -66.686 1.00 35.20  ? 101 TYR D OH  1 
ATOM   5519  N  N   . LYS C 1 102 ? -24.739 68.211  -63.590 1.00 29.79  ? 102 LYS D N   1 
ATOM   5520  C  CA  . LYS C 1 102 ? -24.617 68.933  -62.337 1.00 26.81  ? 102 LYS D CA  1 
ATOM   5521  C  C   . LYS C 1 102 ? -23.390 68.443  -61.592 1.00 25.82  ? 102 LYS D C   1 
ATOM   5522  O  O   . LYS C 1 102 ? -22.883 67.346  -61.831 1.00 22.65  ? 102 LYS D O   1 
ATOM   5523  C  CB  . LYS C 1 102 ? -25.845 68.749  -61.435 1.00 24.55  ? 102 LYS D CB  1 
ATOM   5524  C  CG  . LYS C 1 102 ? -27.114 69.221  -62.048 1.00 33.65  ? 102 LYS D CG  1 
ATOM   5525  C  CD  . LYS C 1 102 ? -28.264 68.321  -61.707 1.00 38.03  ? 102 LYS D CD  1 
ATOM   5526  C  CE  . LYS C 1 102 ? -28.052 67.690  -60.363 1.00 41.81  ? 102 LYS D CE  1 
ATOM   5527  N  NZ  . LYS C 1 102 ? -29.016 66.607  -60.116 1.00 48.75  ? 102 LYS D NZ  1 
ATOM   5528  N  N   . PHE C 1 103 ? -22.921 69.291  -60.686 1.00 23.62  ? 103 PHE D N   1 
ATOM   5529  C  CA  . PHE C 1 103 ? -21.958 68.930  -59.659 1.00 23.00  ? 103 PHE D CA  1 
ATOM   5530  C  C   . PHE C 1 103 ? -22.731 68.744  -58.370 1.00 21.43  ? 103 PHE D C   1 
ATOM   5531  O  O   . PHE C 1 103 ? -23.521 69.611  -57.989 1.00 21.37  ? 103 PHE D O   1 
ATOM   5532  C  CB  . PHE C 1 103 ? -20.884 70.006  -59.461 1.00 21.29  ? 103 PHE D CB  1 
ATOM   5533  C  CG  . PHE C 1 103 ? -19.960 70.163  -60.629 1.00 21.90  ? 103 PHE D CG  1 
ATOM   5534  C  CD1 . PHE C 1 103 ? -19.920 69.194  -61.630 1.00 18.92  ? 103 PHE D CD1 1 
ATOM   5535  C  CD2 . PHE C 1 103 ? -19.166 71.291  -60.747 1.00 15.52  ? 103 PHE D CD2 1 
ATOM   5536  C  CE1 . PHE C 1 103 ? -19.098 69.325  -62.697 1.00 15.46  ? 103 PHE D CE1 1 
ATOM   5537  C  CE2 . PHE C 1 103 ? -18.324 71.435  -61.818 1.00 19.18  ? 103 PHE D CE2 1 
ATOM   5538  C  CZ  . PHE C 1 103 ? -18.291 70.456  -62.802 1.00 24.05  ? 103 PHE D CZ  1 
ATOM   5539  N  N   . VAL C 1 104 ? -22.560 67.593  -57.740 1.00 24.24  ? 104 VAL D N   1 
ATOM   5540  C  CA  . VAL C 1 104 ? -23.200 67.344  -56.464 1.00 20.30  ? 104 VAL D CA  1 
ATOM   5541  C  C   . VAL C 1 104 ? -22.160 66.821  -55.486 1.00 23.64  ? 104 VAL D C   1 
ATOM   5542  O  O   . VAL C 1 104 ? -21.166 66.195  -55.864 1.00 21.86  ? 104 VAL D O   1 
ATOM   5543  C  CB  . VAL C 1 104 ? -24.377 66.350  -56.595 1.00 27.63  ? 104 VAL D CB  1 
ATOM   5544  C  CG1 . VAL C 1 104 ? -25.410 66.844  -57.630 1.00 21.13  ? 104 VAL D CG1 1 
ATOM   5545  C  CG2 . VAL C 1 104 ? -23.848 64.966  -56.919 1.00 25.17  ? 104 VAL D CG2 1 
ATOM   5546  N  N   . ARG C 1 105 ? -22.422 67.066  -54.213 1.00 24.79  ? 105 ARG D N   1 
ATOM   5547  C  CA  . ARG C 1 105 ? -21.668 66.512  -53.108 1.00 22.72  ? 105 ARG D CA  1 
ATOM   5548  C  C   . ARG C 1 105 ? -22.540 65.429  -52.501 1.00 26.29  ? 105 ARG D C   1 
ATOM   5549  O  O   . ARG C 1 105 ? -23.659 65.718  -52.087 1.00 31.03  ? 105 ARG D O   1 
ATOM   5550  C  CB  . ARG C 1 105 ? -21.341 67.591  -52.078 1.00 24.02  ? 105 ARG D CB  1 
ATOM   5551  C  CG  . ARG C 1 105 ? -20.387 67.125  -51.001 1.00 23.26  ? 105 ARG D CG  1 
ATOM   5552  C  CD  . ARG C 1 105 ? -19.583 68.278  -50.506 1.00 30.34  ? 105 ARG D CD  1 
ATOM   5553  N  NE  . ARG C 1 105 ? -18.723 67.875  -49.403 1.00 29.34  ? 105 ARG D NE  1 
ATOM   5554  C  CZ  . ARG C 1 105 ? -17.442 67.580  -49.551 1.00 24.16  ? 105 ARG D CZ  1 
ATOM   5555  N  NH1 . ARG C 1 105 ? -16.851 67.665  -50.733 1.00 23.55  ? 105 ARG D NH1 1 
ATOM   5556  N  NH2 . ARG C 1 105 ? -16.744 67.176  -48.496 1.00 18.03  ? 105 ARG D NH2 1 
ATOM   5557  N  N   . ILE C 1 106 ? -22.094 64.180  -52.554 1.00 25.47  ? 106 ILE D N   1 
ATOM   5558  C  CA  . ILE C 1 106 ? -22.880 63.099  -51.975 1.00 26.69  ? 106 ILE D CA  1 
ATOM   5559  C  C   . ILE C 1 106 ? -22.568 62.968  -50.494 1.00 26.12  ? 106 ILE D C   1 
ATOM   5560  O  O   . ILE C 1 106 ? -21.510 63.374  -50.006 1.00 27.20  ? 106 ILE D O   1 
ATOM   5561  C  CB  . ILE C 1 106 ? -22.665 61.745  -52.666 1.00 29.50  ? 106 ILE D CB  1 
ATOM   5562  C  CG1 . ILE C 1 106 ? -21.182 61.441  -52.765 1.00 23.59  ? 106 ILE D CG1 1 
ATOM   5563  C  CG2 . ILE C 1 106 ? -23.421 61.665  -53.990 1.00 28.26  ? 106 ILE D CG2 1 
ATOM   5564  C  CD1 . ILE C 1 106 ? -20.945 60.041  -53.094 1.00 33.81  ? 106 ILE D CD1 1 
ATOM   5565  N  N   . GLN C 1 107 ? -23.478 62.370  -49.799 1.00 33.55  ? 107 GLN D N   1 
ATOM   5566  C  CA  . GLN C 1 107 ? -23.476 61.996  -48.397 1.00 33.67  ? 107 GLN D CA  1 
ATOM   5567  C  C   . GLN C 1 107 ? -23.018 60.552  -48.273 1.00 31.78  ? 107 GLN D C   1 
ATOM   5568  O  O   . GLN C 1 107 ? -23.296 59.734  -49.157 1.00 28.09  ? 107 GLN D O   1 
ATOM   5569  C  CB  . GLN C 1 107 ? -24.882 62.128  -47.797 1.00 31.46  ? 107 GLN D CB  1 
ATOM   5570  C  CG  . GLN C 1 107 ? -25.245 63.471  -47.139 1.00 48.15  ? 107 GLN D CG  1 
ATOM   5571  C  CD  . GLN C 1 107 ? -24.418 63.812  -45.874 1.00 58.91  ? 107 GLN D CD  1 
ATOM   5572  O  OE1 . GLN C 1 107 ? -24.389 63.029  -44.913 1.00 57.92  ? 107 GLN D OE1 1 
ATOM   5573  N  NE2 . GLN C 1 107 ? -23.791 64.999  -45.853 1.00 49.01  ? 107 GLN D NE2 1 
ATOM   5574  N  N   . PRO C 1 108 ? -22.270 60.217  -47.198 1.00 30.87  ? 108 PRO D N   1 
ATOM   5575  C  CA  . PRO C 1 108 ? -21.877 58.847  -46.961 1.00 26.26  ? 108 PRO D CA  1 
ATOM   5576  C  C   . PRO C 1 108 ? -23.112 57.945  -46.999 1.00 28.79  ? 108 PRO D C   1 
ATOM   5577  O  O   . PRO C 1 108 ? -24.130 58.327  -46.474 1.00 27.22  ? 108 PRO D O   1 
ATOM   5578  C  CB  . PRO C 1 108 ? -21.250 58.908  -45.567 1.00 27.32  ? 108 PRO D CB  1 
ATOM   5579  C  CG  . PRO C 1 108 ? -20.683 60.287  -45.484 1.00 27.74  ? 108 PRO D CG  1 
ATOM   5580  C  CD  . PRO C 1 108 ? -21.735 61.124  -46.167 1.00 28.83  ? 108 PRO D CD  1 
ATOM   5581  N  N   . GLY C 1 109 ? -22.976 56.775  -47.613 1.00 24.67  ? 109 GLY D N   1 
ATOM   5582  C  CA  . GLY C 1 109 ? -24.127 55.880  -47.785 1.00 23.61  ? 109 GLY D CA  1 
ATOM   5583  C  C   . GLY C 1 109 ? -24.688 55.953  -49.189 1.00 28.53  ? 109 GLY D C   1 
ATOM   5584  O  O   . GLY C 1 109 ? -25.434 55.029  -49.520 1.00 24.65  ? 109 GLY D O   1 
ATOM   5585  N  N   A GLN C 1 110 ? -24.411 56.907  -49.865 0.40 29.78  ? 110 GLN D N   1 
ATOM   5586  N  N   B GLN C 1 110 ? -24.384 56.892  -49.879 0.60 28.73  ? 110 GLN D N   1 
ATOM   5587  C  CA  A GLN C 1 110 ? -24.906 56.962  -51.230 0.40 24.97  ? 110 GLN D CA  1 
ATOM   5588  C  CA  B GLN C 1 110 ? -24.892 56.978  -51.239 0.60 24.37  ? 110 GLN D CA  1 
ATOM   5589  C  C   A GLN C 1 110 ? -23.944 56.229  -52.161 0.40 24.00  ? 110 GLN D C   1 
ATOM   5590  C  C   B GLN C 1 110 ? -23.909 56.332  -52.211 0.60 25.06  ? 110 GLN D C   1 
ATOM   5591  O  O   A GLN C 1 110 ? -22.798 55.944  -51.812 0.40 23.83  ? 110 GLN D O   1 
ATOM   5592  O  O   B GLN C 1 110 ? -22.718 56.205  -51.936 0.60 23.46  ? 110 GLN D O   1 
ATOM   5593  C  CB  A GLN C 1 110 ? -25.084 58.409  -51.693 0.40 27.08  ? 110 GLN D CB  1 
ATOM   5594  C  CB  B GLN C 1 110 ? -25.148 58.429  -51.635 0.60 26.30  ? 110 GLN D CB  1 
ATOM   5595  C  CG  A GLN C 1 110 ? -26.074 59.221  -50.883 0.40 28.28  ? 110 GLN D CG  1 
ATOM   5596  C  CG  B GLN C 1 110 ? -26.284 59.069  -50.886 0.60 26.60  ? 110 GLN D CG  1 
ATOM   5597  C  CD  A GLN C 1 110 ? -26.417 60.546  -51.548 0.40 29.76  ? 110 GLN D CD  1 
ATOM   5598  C  CD  B GLN C 1 110 ? -27.501 58.186  -50.832 0.60 23.85  ? 110 GLN D CD  1 
ATOM   5599  O  OE1 A GLN C 1 110 ? -26.080 61.621  -51.039 0.40 25.37  ? 110 GLN D OE1 1 
ATOM   5600  O  OE1 B GLN C 1 110 ? -27.699 57.447  -49.870 0.60 23.72  ? 110 GLN D OE1 1 
ATOM   5601  N  NE2 A GLN C 1 110 ? -27.107 60.473  -52.688 0.40 27.59  ? 110 GLN D NE2 1 
ATOM   5602  N  NE2 B GLN C 1 110 ? -28.326 58.252  -51.863 0.60 24.32  ? 110 GLN D NE2 1 
ATOM   5603  N  N   . THR C 1 111 ? -24.429 55.912  -53.355 1.00 20.99  ? 111 THR D N   1 
ATOM   5604  C  CA  . THR C 1 111 ? -23.656 55.179  -54.342 1.00 25.15  ? 111 THR D CA  1 
ATOM   5605  C  C   . THR C 1 111 ? -23.468 56.017  -55.593 1.00 22.15  ? 111 THR D C   1 
ATOM   5606  O  O   . THR C 1 111 ? -24.159 57.016  -55.804 1.00 20.47  ? 111 THR D O   1 
ATOM   5607  C  CB  . THR C 1 111 ? -24.359 53.873  -54.717 1.00 22.41  ? 111 THR D CB  1 
ATOM   5608  O  OG1 . THR C 1 111 ? -25.699 54.199  -55.125 1.00 21.73  ? 111 THR D OG1 1 
ATOM   5609  C  CG2 . THR C 1 111 ? -24.365 52.919  -53.547 1.00 19.84  ? 111 THR D CG2 1 
ATOM   5610  N  N   . PHE C 1 112 ? -22.539 55.569  -56.434 1.00 19.32  ? 112 PHE D N   1 
ATOM   5611  C  CA  . PHE C 1 112 ? -22.309 56.206  -57.724 1.00 22.93  ? 112 PHE D CA  1 
ATOM   5612  C  C   . PHE C 1 112 ? -21.466 55.265  -58.569 1.00 20.98  ? 112 PHE D C   1 
ATOM   5613  O  O   . PHE C 1 112 ? -20.839 54.347  -58.047 1.00 22.55  ? 112 PHE D O   1 
ATOM   5614  C  CB  . PHE C 1 112 ? -21.631 57.588  -57.575 1.00 19.84  ? 112 PHE D CB  1 
ATOM   5615  C  CG  . PHE C 1 112 ? -20.291 57.574  -56.847 1.00 25.55  ? 112 PHE D CG  1 
ATOM   5616  C  CD1 . PHE C 1 112 ? -19.108 57.305  -57.528 1.00 22.36  ? 112 PHE D CD1 1 
ATOM   5617  C  CD2 . PHE C 1 112 ? -20.207 57.879  -55.495 1.00 28.25  ? 112 PHE D CD2 1 
ATOM   5618  C  CE1 . PHE C 1 112 ? -17.886 57.302  -56.870 1.00 19.34  ? 112 PHE D CE1 1 
ATOM   5619  C  CE2 . PHE C 1 112 ? -18.965 57.892  -54.826 1.00 26.77  ? 112 PHE D CE2 1 
ATOM   5620  C  CZ  . PHE C 1 112 ? -17.818 57.606  -55.507 1.00 24.68  ? 112 PHE D CZ  1 
ATOM   5621  N  N   . SER C 1 113 ? -21.446 55.515  -59.877 1.00 22.38  ? 113 SER D N   1 
ATOM   5622  C  CA  . SER C 1 113 ? -20.623 54.743  -60.805 1.00 21.33  ? 113 SER D CA  1 
ATOM   5623  C  C   . SER C 1 113 ? -19.286 55.436  -61.042 1.00 25.29  ? 113 SER D C   1 
ATOM   5624  O  O   . SER C 1 113 ? -19.185 56.665  -61.013 1.00 22.66  ? 113 SER D O   1 
ATOM   5625  C  CB  . SER C 1 113 ? -21.346 54.555  -62.136 1.00 21.83  ? 113 SER D CB  1 
ATOM   5626  O  OG  . SER C 1 113 ? -22.667 54.071  -61.927 1.00 20.78  ? 113 SER D OG  1 
ATOM   5627  N  N   . VAL C 1 114 ? -18.248 54.632  -61.261 1.00 26.22  ? 114 VAL D N   1 
ATOM   5628  C  CA  . VAL C 1 114 ? -16.900 55.131  -61.519 1.00 22.55  ? 114 VAL D CA  1 
ATOM   5629  C  C   . VAL C 1 114 ? -16.484 54.691  -62.917 1.00 22.47  ? 114 VAL D C   1 
ATOM   5630  O  O   . VAL C 1 114 ? -16.522 53.498  -63.232 1.00 21.27  ? 114 VAL D O   1 
ATOM   5631  C  CB  . VAL C 1 114 ? -15.890 54.629  -60.466 1.00 20.94  ? 114 VAL D CB  1 
ATOM   5632  C  CG1 . VAL C 1 114 ? -14.466 55.073  -60.803 1.00 17.97  ? 114 VAL D CG1 1 
ATOM   5633  C  CG2 . VAL C 1 114 ? -16.267 55.132  -59.089 1.00 22.46  ? 114 VAL D CG2 1 
ATOM   5634  N  N   . LEU C 1 115 ? -16.088 55.648  -63.751 1.00 22.11  ? 115 LEU D N   1 
ATOM   5635  C  CA  . LEU C 1 115 ? -15.456 55.353  -65.031 1.00 21.85  ? 115 LEU D CA  1 
ATOM   5636  C  C   . LEU C 1 115 ? -13.959 55.529  -64.812 1.00 21.70  ? 115 LEU D C   1 
ATOM   5637  O  O   . LEU C 1 115 ? -13.447 56.649  -64.814 1.00 25.82  ? 115 LEU D O   1 
ATOM   5638  C  CB  . LEU C 1 115 ? -15.989 56.262  -66.133 1.00 19.85  ? 115 LEU D CB  1 
ATOM   5639  C  CG  . LEU C 1 115 ? -15.434 56.087  -67.557 1.00 26.92  ? 115 LEU D CG  1 
ATOM   5640  C  CD1 . LEU C 1 115 ? -15.925 54.773  -68.191 1.00 24.28  ? 115 LEU D CD1 1 
ATOM   5641  C  CD2 . LEU C 1 115 ? -15.741 57.321  -68.473 1.00 23.76  ? 115 LEU D CD2 1 
ATOM   5642  N  N   . ALA C 1 116 ? -13.262 54.431  -64.570 1.00 22.77  ? 116 ALA D N   1 
ATOM   5643  C  CA  . ALA C 1 116 ? -11.828 54.494  -64.328 1.00 25.09  ? 116 ALA D CA  1 
ATOM   5644  C  C   . ALA C 1 116 ? -11.096 54.693  -65.653 1.00 23.15  ? 116 ALA D C   1 
ATOM   5645  O  O   . ALA C 1 116 ? -11.331 53.959  -66.619 1.00 23.20  ? 116 ALA D O   1 
ATOM   5646  C  CB  . ALA C 1 116 ? -11.349 53.230  -63.618 1.00 23.73  ? 116 ALA D CB  1 
ATOM   5647  N  N   . CYS C 1 117 ? -10.229 55.703  -65.708 1.00 23.49  ? 117 CYS D N   1 
ATOM   5648  C  CA  . CYS C 1 117 ? -9.590  56.106  -66.957 1.00 24.56  ? 117 CYS D CA  1 
ATOM   5649  C  C   . CYS C 1 117 ? -8.081  56.206  -66.802 1.00 24.60  ? 117 CYS D C   1 
ATOM   5650  O  O   . CYS C 1 117 ? -7.568  56.443  -65.709 1.00 23.83  ? 117 CYS D O   1 
ATOM   5651  C  CB  . CYS C 1 117 ? -10.124 57.451  -67.439 1.00 22.55  ? 117 CYS D CB  1 
ATOM   5652  S  SG  . CYS C 1 117 ? -11.818 57.402  -67.912 1.00 25.88  ? 117 CYS D SG  1 
ATOM   5653  N  N   . TYR C 1 118 ? -7.376  56.051  -67.928 1.00 27.10  ? 118 TYR D N   1 
ATOM   5654  C  CA  . TYR C 1 118 ? -5.931  56.250  -67.988 1.00 26.52  ? 118 TYR D CA  1 
ATOM   5655  C  C   . TYR C 1 118 ? -5.567  56.914  -69.310 1.00 27.04  ? 118 TYR D C   1 
ATOM   5656  O  O   . TYR C 1 118 ? -5.901  56.403  -70.383 1.00 27.13  ? 118 TYR D O   1 
ATOM   5657  C  CB  . TYR C 1 118 ? -5.183  54.919  -67.826 1.00 23.91  ? 118 TYR D CB  1 
ATOM   5658  C  CG  . TYR C 1 118 ? -5.527  54.221  -66.524 1.00 28.37  ? 118 TYR D CG  1 
ATOM   5659  C  CD1 . TYR C 1 118 ? -4.853  54.533  -65.344 1.00 25.79  ? 118 TYR D CD1 1 
ATOM   5660  C  CD2 . TYR C 1 118 ? -6.549  53.271  -66.465 1.00 27.22  ? 118 TYR D CD2 1 
ATOM   5661  C  CE1 . TYR C 1 118 ? -5.179  53.920  -64.162 1.00 25.09  ? 118 TYR D CE1 1 
ATOM   5662  C  CE2 . TYR C 1 118 ? -6.883  52.651  -65.271 1.00 25.91  ? 118 TYR D CE2 1 
ATOM   5663  C  CZ  . TYR C 1 118 ? -6.193  52.984  -64.133 1.00 25.83  ? 118 TYR D CZ  1 
ATOM   5664  O  OH  . TYR C 1 118 ? -6.515  52.371  -62.955 1.00 30.04  ? 118 TYR D OH  1 
ATOM   5665  N  N   . ASN C 1 119 ? -4.850  58.036  -69.233 1.00 27.62  ? 119 ASN D N   1 
ATOM   5666  C  CA  . ASN C 1 119 ? -4.492  58.807  -70.426 1.00 28.28  ? 119 ASN D CA  1 
ATOM   5667  C  C   . ASN C 1 119 ? -5.735  59.282  -71.174 1.00 23.99  ? 119 ASN D C   1 
ATOM   5668  O  O   . ASN C 1 119 ? -5.814  59.191  -72.399 1.00 28.42  ? 119 ASN D O   1 
ATOM   5669  C  CB  . ASN C 1 119 ? -3.580  58.006  -71.354 1.00 28.22  ? 119 ASN D CB  1 
ATOM   5670  C  CG  . ASN C 1 119 ? -2.457  57.348  -70.617 1.00 28.83  ? 119 ASN D CG  1 
ATOM   5671  O  OD1 . ASN C 1 119 ? -1.570  58.029  -70.124 1.00 35.86  ? 119 ASN D OD1 1 
ATOM   5672  N  ND2 . ASN C 1 119 ? -2.488  56.022  -70.522 1.00 29.52  ? 119 ASN D ND2 1 
ATOM   5673  N  N   . GLY C 1 120 ? -6.741  59.730  -70.429 1.00 23.63  ? 120 GLY D N   1 
ATOM   5674  C  CA  . GLY C 1 120 ? -7.950  60.240  -71.038 1.00 20.93  ? 120 GLY D CA  1 
ATOM   5675  C  C   . GLY C 1 120 ? -8.809  59.225  -71.762 1.00 27.43  ? 120 GLY D C   1 
ATOM   5676  O  O   . GLY C 1 120 ? -9.680  59.628  -72.540 1.00 29.81  ? 120 GLY D O   1 
ATOM   5677  N  N   . SER C 1 121 ? -8.597  57.925  -71.571 1.00 26.90  ? 121 SER D N   1 
ATOM   5678  C  CA  . SER C 1 121 ? -9.548  57.021  -72.199 1.00 31.31  ? 121 SER D CA  1 
ATOM   5679  C  C   . SER C 1 121 ? -10.070 55.975  -71.216 1.00 21.86  ? 121 SER D C   1 
ATOM   5680  O  O   . SER C 1 121 ? -9.382  55.593  -70.270 1.00 22.83  ? 121 SER D O   1 
ATOM   5681  C  CB  . SER C 1 121 ? -8.935  56.370  -73.453 1.00 27.64  ? 121 SER D CB  1 
ATOM   5682  O  OG  . SER C 1 121 ? -7.633  55.938  -73.195 1.00 32.92  ? 121 SER D OG  1 
ATOM   5683  N  N   . PRO C 1 122 ? -11.311 55.542  -71.395 1.00 28.67  ? 122 PRO D N   1 
ATOM   5684  C  CA  . PRO C 1 122 ? -11.968 54.708  -70.375 1.00 28.80  ? 122 PRO D CA  1 
ATOM   5685  C  C   . PRO C 1 122 ? -11.444 53.278  -70.315 1.00 26.59  ? 122 PRO D C   1 
ATOM   5686  O  O   . PRO C 1 122 ? -11.127 52.662  -71.334 1.00 29.24  ? 122 PRO D O   1 
ATOM   5687  C  CB  . PRO C 1 122 ? -13.432 54.722  -70.822 1.00 29.76  ? 122 PRO D CB  1 
ATOM   5688  C  CG  . PRO C 1 122 ? -13.343 54.839  -72.306 1.00 30.26  ? 122 PRO D CG  1 
ATOM   5689  C  CD  . PRO C 1 122 ? -12.196 55.797  -72.548 1.00 29.88  ? 122 PRO D CD  1 
ATOM   5690  N  N   . SER C 1 123 ? -11.371 52.745  -69.098 1.00 29.49  ? 123 SER D N   1 
ATOM   5691  C  CA  . SER C 1 123 ? -10.926 51.372  -68.862 1.00 30.39  ? 123 SER D CA  1 
ATOM   5692  C  C   . SER C 1 123 ? -12.050 50.435  -68.430 1.00 32.03  ? 123 SER D C   1 
ATOM   5693  O  O   . SER C 1 123 ? -12.129 49.290  -68.916 1.00 31.34  ? 123 SER D O   1 
ATOM   5694  C  CB  . SER C 1 123 ? -9.823  51.361  -67.797 1.00 31.58  ? 123 SER D CB  1 
ATOM   5695  O  OG  . SER C 1 123 ? -9.356  50.052  -67.562 1.00 33.86  ? 123 SER D OG  1 
ATOM   5696  N  N   . GLY C 1 124 ? -12.928 50.899  -67.549 1.00 22.82  ? 124 GLY D N   1 
ATOM   5697  C  CA  . GLY C 1 124 ? -14.006 50.074  -67.046 1.00 21.92  ? 124 GLY D CA  1 
ATOM   5698  C  C   . GLY C 1 124 ? -14.894 50.908  -66.147 1.00 24.71  ? 124 GLY D C   1 
ATOM   5699  O  O   . GLY C 1 124 ? -14.512 51.993  -65.685 1.00 24.00  ? 124 GLY D O   1 
ATOM   5700  N  N   . VAL C 1 125 ? -16.075 50.367  -65.874 1.00 19.99  ? 125 VAL D N   1 
ATOM   5701  C  CA  . VAL C 1 125 ? -17.073 51.055  -65.070 1.00 21.63  ? 125 VAL D CA  1 
ATOM   5702  C  C   . VAL C 1 125 ? -17.547 50.117  -63.958 1.00 21.47  ? 125 VAL D C   1 
ATOM   5703  O  O   . VAL C 1 125 ? -17.696 48.907  -64.167 1.00 24.75  ? 125 VAL D O   1 
ATOM   5704  C  CB  . VAL C 1 125 ? -18.237 51.557  -65.958 1.00 24.39  ? 125 VAL D CB  1 
ATOM   5705  C  CG1 . VAL C 1 125 ? -18.996 50.396  -66.536 1.00 27.59  ? 125 VAL D CG1 1 
ATOM   5706  C  CG2 . VAL C 1 125 ? -19.161 52.515  -65.218 1.00 24.05  ? 125 VAL D CG2 1 
ATOM   5707  N  N   . TYR C 1 126 ? -17.705 50.666  -62.754 1.00 21.17  ? 126 TYR D N   1 
ATOM   5708  C  CA  . TYR C 1 126 ? -18.143 49.906  -61.594 1.00 23.02  ? 126 TYR D CA  1 
ATOM   5709  C  C   . TYR C 1 126 ? -18.838 50.830  -60.606 1.00 27.56  ? 126 TYR D C   1 
ATOM   5710  O  O   . TYR C 1 126 ? -18.653 52.056  -60.622 1.00 27.01  ? 126 TYR D O   1 
ATOM   5711  C  CB  . TYR C 1 126 ? -16.975 49.178  -60.907 1.00 26.53  ? 126 TYR D CB  1 
ATOM   5712  C  CG  . TYR C 1 126 ? -15.792 50.037  -60.508 1.00 25.42  ? 126 TYR D CG  1 
ATOM   5713  C  CD1 . TYR C 1 126 ? -15.805 50.792  -59.334 1.00 27.58  ? 126 TYR D CD1 1 
ATOM   5714  C  CD2 . TYR C 1 126 ? -14.641 50.074  -61.293 1.00 27.12  ? 126 TYR D CD2 1 
ATOM   5715  C  CE1 . TYR C 1 126 ? -14.714 51.583  -58.977 1.00 26.15  ? 126 TYR D CE1 1 
ATOM   5716  C  CE2 . TYR C 1 126 ? -13.556 50.857  -60.941 1.00 23.43  ? 126 TYR D CE2 1 
ATOM   5717  C  CZ  . TYR C 1 126 ? -13.595 51.606  -59.786 1.00 23.46  ? 126 TYR D CZ  1 
ATOM   5718  O  OH  . TYR C 1 126 ? -12.498 52.376  -59.442 1.00 27.07  ? 126 TYR D OH  1 
ATOM   5719  N  N   . GLN C 1 127 ? -19.657 50.216  -59.755 1.00 28.02  ? 127 GLN D N   1 
ATOM   5720  C  CA  . GLN C 1 127 ? -20.326 50.882  -58.644 1.00 28.28  ? 127 GLN D CA  1 
ATOM   5721  C  C   . GLN C 1 127 ? -19.477 50.848  -57.385 1.00 29.10  ? 127 GLN D C   1 
ATOM   5722  O  O   . GLN C 1 127 ? -18.742 49.893  -57.129 1.00 32.65  ? 127 GLN D O   1 
ATOM   5723  C  CB  . GLN C 1 127 ? -21.653 50.211  -58.305 1.00 22.93  ? 127 GLN D CB  1 
ATOM   5724  C  CG  . GLN C 1 127 ? -22.764 50.551  -59.210 1.00 27.31  ? 127 GLN D CG  1 
ATOM   5725  C  CD  . GLN C 1 127 ? -23.341 51.913  -58.961 1.00 22.91  ? 127 GLN D CD  1 
ATOM   5726  O  OE1 . GLN C 1 127 ? -23.121 52.828  -59.741 1.00 28.64  ? 127 GLN D OE1 1 
ATOM   5727  N  NE2 . GLN C 1 127 ? -24.132 52.045  -57.914 1.00 24.01  ? 127 GLN D NE2 1 
ATOM   5728  N  N   . CYS C 1 128 ? -19.604 51.893  -56.585 1.00 25.36  ? 128 CYS D N   1 
ATOM   5729  C  CA  . CYS C 1 128 ? -19.172 51.822  -55.201 1.00 26.96  ? 128 CYS D CA  1 
ATOM   5730  C  C   . CYS C 1 128 ? -19.964 52.857  -54.424 1.00 20.51  ? 128 CYS D C   1 
ATOM   5731  O  O   . CYS C 1 128 ? -20.870 53.499  -54.952 1.00 26.41  ? 128 CYS D O   1 
ATOM   5732  C  CB  . CYS C 1 128 ? -17.660 51.999  -55.067 1.00 34.38  ? 128 CYS D CB  1 
ATOM   5733  S  SG  . CYS C 1 128 ? -16.969 53.336  -56.019 1.00 40.93  ? 128 CYS D SG  1 
ATOM   5734  N  N   . ALA C 1 129 ? -19.685 52.950  -53.145 1.00 22.17  ? 129 ALA D N   1 
ATOM   5735  C  CA  . ALA C 1 129 ? -20.448 53.812  -52.262 1.00 25.62  ? 129 ALA D CA  1 
ATOM   5736  C  C   . ALA C 1 129 ? -19.502 54.707  -51.482 1.00 24.49  ? 129 ALA D C   1 
ATOM   5737  O  O   . ALA C 1 129 ? -18.354 54.345  -51.203 1.00 22.70  ? 129 ALA D O   1 
ATOM   5738  C  CB  . ALA C 1 129 ? -21.328 52.999  -51.286 1.00 23.47  ? 129 ALA D CB  1 
ATOM   5739  N  N   . MET C 1 130 ? -20.000 55.877  -51.128 1.00 24.78  ? 130 MET D N   1 
ATOM   5740  C  CA  . MET C 1 130 ? -19.236 56.747  -50.215 1.00 26.80  ? 130 MET D CA  1 
ATOM   5741  C  C   . MET C 1 130 ? -19.437 56.170  -48.814 1.00 27.63  ? 130 MET D C   1 
ATOM   5742  O  O   . MET C 1 130 ? -20.580 56.110  -48.367 1.00 24.44  ? 130 MET D O   1 
ATOM   5743  C  CB  . MET C 1 130 ? -19.738 58.189  -50.241 1.00 28.53  ? 130 MET D CB  1 
ATOM   5744  C  CG  . MET C 1 130 ? -19.030 59.084  -49.254 1.00 26.69  ? 130 MET D CG  1 
ATOM   5745  S  SD  . MET C 1 130 ? -17.298 59.261  -49.701 1.00 38.90  ? 130 MET D SD  1 
ATOM   5746  C  CE  . MET C 1 130 ? -17.457 60.105  -51.272 1.00 32.77  ? 130 MET D CE  1 
ATOM   5747  N  N   . ARG C 1 131 ? -18.353 55.764  -48.175 1.00 24.44  ? 131 ARG D N   1 
ATOM   5748  C  CA  . ARG C 1 131 ? -18.412 55.159  -46.831 1.00 23.30  ? 131 ARG D CA  1 
ATOM   5749  C  C   . ARG C 1 131 ? -18.437 56.265  -45.773 1.00 26.98  ? 131 ARG D C   1 
ATOM   5750  O  O   . ARG C 1 131 ? -18.106 57.405  -46.110 1.00 27.85  ? 131 ARG D O   1 
ATOM   5751  C  CB  . ARG C 1 131 ? -17.249 54.180  -46.670 1.00 23.87  ? 131 ARG D CB  1 
ATOM   5752  C  CG  . ARG C 1 131 ? -16.992 53.273  -47.863 1.00 25.24  ? 131 ARG D CG  1 
ATOM   5753  C  CD  . ARG C 1 131 ? -17.904 52.070  -47.998 1.00 25.33  ? 131 ARG D CD  1 
ATOM   5754  N  NE  . ARG C 1 131 ? -18.294 51.438  -46.747 1.00 30.96  ? 131 ARG D NE  1 
ATOM   5755  C  CZ  . ARG C 1 131 ? -19.174 50.450  -46.654 1.00 24.56  ? 131 ARG D CZ  1 
ATOM   5756  N  NH1 . ARG C 1 131 ? -19.744 49.969  -47.743 1.00 17.78  ? 131 ARG D NH1 1 
ATOM   5757  N  NH2 . ARG C 1 131 ? -19.473 49.937  -45.477 1.00 25.49  ? 131 ARG D NH2 1 
ATOM   5758  N  N   . HIS C 1 132 ? -18.813 55.920  -44.548 1.00 24.76  ? 132 HIS D N   1 
ATOM   5759  C  CA  . HIS C 1 132 ? -18.945 56.895  -43.437 1.00 29.60  ? 132 HIS D CA  1 
ATOM   5760  C  C   . HIS C 1 132 ? -17.569 57.406  -42.996 1.00 28.43  ? 132 HIS D C   1 
ATOM   5761  O  O   . HIS C 1 132 ? -17.547 58.340  -42.210 1.00 30.30  ? 132 HIS D O   1 
ATOM   5762  C  CB  . HIS C 1 132 ? -19.802 56.255  -42.341 1.00 32.08  ? 132 HIS D CB  1 
ATOM   5763  C  CG  . HIS C 1 132 ? -21.250 56.180  -42.680 1.00 30.31  ? 132 HIS D CG  1 
ATOM   5764  N  ND1 . HIS C 1 132 ? -21.779 55.153  -43.425 1.00 29.33  ? 132 HIS D ND1 1 
ATOM   5765  C  CD2 . HIS C 1 132 ? -22.276 57.003  -42.388 1.00 28.36  ? 132 HIS D CD2 1 
ATOM   5766  C  CE1 . HIS C 1 132 ? -23.068 55.347  -43.582 1.00 31.05  ? 132 HIS D CE1 1 
ATOM   5767  N  NE2 . HIS C 1 132 ? -23.397 56.471  -42.955 1.00 31.29  ? 132 HIS D NE2 1 
ATOM   5768  N  N   . ASN C 1 133 ? -16.482 56.804  -43.482 1.00 26.77  ? 133 ASN D N   1 
ATOM   5769  C  CA  . ASN C 1 133 ? -15.118 57.335  -43.235 1.00 25.02  ? 133 ASN D CA  1 
ATOM   5770  C  C   . ASN C 1 133 ? -14.684 58.150  -44.462 1.00 23.68  ? 133 ASN D C   1 
ATOM   5771  O  O   . ASN C 1 133 ? -13.499 58.446  -44.545 1.00 28.89  ? 133 ASN D O   1 
ATOM   5772  C  CB  . ASN C 1 133 ? -14.116 56.238  -42.862 1.00 25.93  ? 133 ASN D CB  1 
ATOM   5773  C  CG  . ASN C 1 133 ? -13.902 55.187  -43.930 1.00 26.07  ? 133 ASN D CG  1 
ATOM   5774  O  OD1 . ASN C 1 133 ? -14.567 55.178  -44.961 1.00 23.21  ? 133 ASN D OD1 1 
ATOM   5775  N  ND2 . ASN C 1 133 ? -12.965 54.291  -43.684 1.00 29.72  ? 133 ASN D ND2 1 
ATOM   5776  N  N   . PHE C 1 134 ? -15.603 58.447  -45.386 1.00 25.35  ? 134 PHE D N   1 
ATOM   5777  C  CA  . PHE C 1 134 ? -15.348 59.317  -46.570 1.00 26.32  ? 134 PHE D CA  1 
ATOM   5778  C  C   . PHE C 1 134 ? -14.378 58.701  -47.581 1.00 29.79  ? 134 PHE D C   1 
ATOM   5779  O  O   . PHE C 1 134 ? -13.786 59.457  -48.334 1.00 32.71  ? 134 PHE D O   1 
ATOM   5780  C  CB  . PHE C 1 134 ? -14.937 60.710  -46.105 1.00 21.68  ? 134 PHE D CB  1 
ATOM   5781  C  CG  . PHE C 1 134 ? -15.966 61.321  -45.195 1.00 28.97  ? 134 PHE D CG  1 
ATOM   5782  C  CD1 . PHE C 1 134 ? -17.070 61.969  -45.719 1.00 22.58  ? 134 PHE D CD1 1 
ATOM   5783  C  CD2 . PHE C 1 134 ? -15.867 61.192  -43.821 1.00 24.72  ? 134 PHE D CD2 1 
ATOM   5784  C  CE1 . PHE C 1 134 ? -18.035 62.509  -44.886 1.00 22.27  ? 134 PHE D CE1 1 
ATOM   5785  C  CE2 . PHE C 1 134 ? -16.835 61.729  -42.992 1.00 25.96  ? 134 PHE D CE2 1 
ATOM   5786  C  CZ  . PHE C 1 134 ? -17.914 62.389  -43.525 1.00 23.57  ? 134 PHE D CZ  1 
ATOM   5787  N  N   . THR C 1 135 ? -14.250 57.381  -47.601 1.00 24.65  ? 135 THR D N   1 
ATOM   5788  C  CA  . THR C 1 135 ? -13.440 56.722  -48.608 1.00 23.14  ? 135 THR D CA  1 
ATOM   5789  C  C   . THR C 1 135 ? -14.356 55.912  -49.501 1.00 21.03  ? 135 THR D C   1 
ATOM   5790  O  O   . THR C 1 135 ? -15.532 55.708  -49.196 1.00 27.43  ? 135 THR D O   1 
ATOM   5791  C  CB  . THR C 1 135 ? -12.400 55.797  -47.961 1.00 25.53  ? 135 THR D CB  1 
ATOM   5792  O  OG1 . THR C 1 135 ? -13.079 54.817  -47.156 1.00 28.32  ? 135 THR D OG1 1 
ATOM   5793  C  CG2 . THR C 1 135 ? -11.465 56.597  -47.063 1.00 30.97  ? 135 THR D CG2 1 
ATOM   5794  N  N   . ILE C 1 136 ? -13.799 55.389  -50.580 1.00 24.47  ? 136 ILE D N   1 
ATOM   5795  C  CA  . ILE C 1 136 ? -14.527 54.433  -51.399 1.00 24.92  ? 136 ILE D CA  1 
ATOM   5796  C  C   . ILE C 1 136 ? -13.614 53.249  -51.639 1.00 25.36  ? 136 ILE D C   1 
ATOM   5797  O  O   . ILE C 1 136 ? -12.393 53.324  -51.470 1.00 23.10  ? 136 ILE D O   1 
ATOM   5798  C  CB  . ILE C 1 136 ? -15.020 55.008  -52.747 1.00 25.61  ? 136 ILE D CB  1 
ATOM   5799  C  CG1 . ILE C 1 136 ? -13.829 55.366  -53.632 1.00 23.32  ? 136 ILE D CG1 1 
ATOM   5800  C  CG2 . ILE C 1 136 ? -15.958 56.197  -52.538 1.00 23.68  ? 136 ILE D CG2 1 
ATOM   5801  C  CD1 . ILE C 1 136 ? -14.241 55.568  -55.039 1.00 23.27  ? 136 ILE D CD1 1 
ATOM   5802  N  N   . LYS C 1 137 ? -14.239 52.136  -51.992 1.00 25.04  ? 137 LYS D N   1 
ATOM   5803  C  CA  . LYS C 1 137 ? -13.552 50.887  -52.294 1.00 26.78  ? 137 LYS D CA  1 
ATOM   5804  C  C   . LYS C 1 137 ? -13.569 50.737  -53.809 1.00 29.70  ? 137 LYS D C   1 
ATOM   5805  O  O   . LYS C 1 137 ? -14.439 50.083  -54.380 1.00 28.10  ? 137 LYS D O   1 
ATOM   5806  C  CB  . LYS C 1 137 ? -14.234 49.719  -51.579 1.00 28.90  ? 137 LYS D CB  1 
ATOM   5807  C  CG  . LYS C 1 137 ? -14.238 49.923  -50.062 1.00 29.37  ? 137 LYS D CG  1 
ATOM   5808  C  CD  . LYS C 1 137 ? -15.044 48.898  -49.284 1.00 31.87  ? 137 LYS D CD  1 
ATOM   5809  C  CE  . LYS C 1 137 ? -14.692 49.022  -47.777 1.00 37.40  ? 137 LYS D CE  1 
ATOM   5810  N  NZ  . LYS C 1 137 ? -15.501 48.119  -46.884 1.00 38.77  ? 137 LYS D NZ  1 
ATOM   5811  N  N   . GLY C 1 138 ? -12.586 51.341  -54.470 1.00 23.13  ? 138 GLY D N   1 
ATOM   5812  C  CA  . GLY C 1 138 ? -12.508 51.307  -55.898 1.00 27.12  ? 138 GLY D CA  1 
ATOM   5813  C  C   . GLY C 1 138 ? -11.377 50.438  -56.407 1.00 24.08  ? 138 GLY D C   1 
ATOM   5814  O  O   . GLY C 1 138 ? -10.817 49.602  -55.686 1.00 26.72  ? 138 GLY D O   1 
ATOM   5815  N  N   . SER C 1 139 ? -11.049 50.632  -57.679 1.00 22.85  ? 139 SER D N   1 
ATOM   5816  C  CA  . SER C 1 139 ? -9.961  49.937  -58.370 1.00 28.28  ? 139 SER D CA  1 
ATOM   5817  C  C   . SER C 1 139 ? -9.244  50.994  -59.222 1.00 22.00  ? 139 SER D C   1 
ATOM   5818  O  O   . SER C 1 139 ? -9.746  51.389  -60.277 1.00 22.64  ? 139 SER D O   1 
ATOM   5819  C  CB  . SER C 1 139 ? -10.528 48.783  -59.196 1.00 20.57  ? 139 SER D CB  1 
ATOM   5820  O  OG  . SER C 1 139 ? -9.634  48.324  -60.177 1.00 20.28  ? 139 SER D OG  1 
ATOM   5821  N  N   . PHE C 1 140 ? -8.113  51.502  -58.727 1.00 23.06  ? 140 PHE D N   1 
ATOM   5822  C  CA  . PHE C 1 140 ? -7.430  52.663  -59.308 1.00 24.77  ? 140 PHE D CA  1 
ATOM   5823  C  C   . PHE C 1 140 ? -5.934  52.403  -59.314 1.00 28.07  ? 140 PHE D C   1 
ATOM   5824  O  O   . PHE C 1 140 ? -5.377  52.002  -58.292 1.00 30.67  ? 140 PHE D O   1 
ATOM   5825  C  CB  . PHE C 1 140 ? -7.674  53.958  -58.529 1.00 25.92  ? 140 PHE D CB  1 
ATOM   5826  C  CG  . PHE C 1 140 ? -9.074  54.484  -58.596 1.00 23.56  ? 140 PHE D CG  1 
ATOM   5827  C  CD1 . PHE C 1 140 ? -9.570  55.034  -59.759 1.00 25.76  ? 140 PHE D CD1 1 
ATOM   5828  C  CD2 . PHE C 1 140 ? -9.869  54.506  -57.460 1.00 26.11  ? 140 PHE D CD2 1 
ATOM   5829  C  CE1 . PHE C 1 140 ? -10.858 55.557  -59.801 1.00 27.53  ? 140 PHE D CE1 1 
ATOM   5830  C  CE2 . PHE C 1 140 ? -11.154 55.021  -57.492 1.00 27.80  ? 140 PHE D CE2 1 
ATOM   5831  C  CZ  . PHE C 1 140 ? -11.649 55.552  -58.654 1.00 24.14  ? 140 PHE D CZ  1 
ATOM   5832  N  N   . LEU C 1 141 ? -5.290  52.624  -60.449 1.00 28.58  ? 141 LEU D N   1 
ATOM   5833  C  CA  . LEU C 1 141 ? -3.855  52.442  -60.628 1.00 28.30  ? 141 LEU D CA  1 
ATOM   5834  C  C   . LEU C 1 141 ? -3.223  53.801  -60.921 1.00 26.78  ? 141 LEU D C   1 
ATOM   5835  O  O   . LEU C 1 141 ? -3.912  54.822  -60.991 1.00 26.91  ? 141 LEU D O   1 
ATOM   5836  C  CB  . LEU C 1 141 ? -3.573  51.460  -61.769 1.00 24.07  ? 141 LEU D CB  1 
ATOM   5837  C  CG  . LEU C 1 141 ? -4.164  50.054  -61.677 1.00 28.86  ? 141 LEU D CG  1 
ATOM   5838  C  CD1 . LEU C 1 141 ? -3.999  49.324  -63.011 1.00 33.02  ? 141 LEU D CD1 1 
ATOM   5839  C  CD2 . LEU C 1 141 ? -3.509  49.263  -60.575 1.00 31.43  ? 141 LEU D CD2 1 
ATOM   5840  N  N   . ASN C 1 142 ? -1.900  53.810  -61.097 1.00 28.67  ? 142 ASN D N   1 
ATOM   5841  C  CA  . ASN C 1 142 ? -1.220  55.017  -61.555 1.00 26.15  ? 142 ASN D CA  1 
ATOM   5842  C  C   . ASN C 1 142 ? -1.841  55.524  -62.847 1.00 24.81  ? 142 ASN D C   1 
ATOM   5843  O  O   . ASN C 1 142 ? -1.999  54.776  -63.812 1.00 31.27  ? 142 ASN D O   1 
ATOM   5844  C  CB  . ASN C 1 142 ? 0.267   54.760  -61.770 1.00 25.05  ? 142 ASN D CB  1 
ATOM   5845  C  CG  . ASN C 1 142 ? 1.027   54.610  -60.475 1.00 30.49  ? 142 ASN D CG  1 
ATOM   5846  O  OD1 . ASN C 1 142 ? 0.626   55.150  -59.439 1.00 29.86  ? 142 ASN D OD1 1 
ATOM   5847  N  ND2 . ASN C 1 142 ? 2.166   53.919  -60.533 1.00 27.83  ? 142 ASN D ND2 1 
ATOM   5848  N  N   . GLY C 1 143 ? -2.176  56.804  -62.863 1.00 27.26  ? 143 GLY D N   1 
ATOM   5849  C  CA  . GLY C 1 143 ? -2.798  57.439  -64.003 1.00 26.28  ? 143 GLY D CA  1 
ATOM   5850  C  C   . GLY C 1 143 ? -4.299  57.540  -63.916 1.00 26.79  ? 143 GLY D C   1 
ATOM   5851  O  O   . GLY C 1 143 ? -4.918  58.126  -64.808 1.00 23.46  ? 143 GLY D O   1 
ATOM   5852  N  N   . SER C 1 144 ? -4.906  56.997  -62.866 1.00 23.89  ? 144 SER D N   1 
ATOM   5853  C  CA  . SER C 1 144 ? -6.342  57.080  -62.721 1.00 24.24  ? 144 SER D CA  1 
ATOM   5854  C  C   . SER C 1 144 ? -6.805  58.403  -62.121 1.00 20.04  ? 144 SER D C   1 
ATOM   5855  O  O   . SER C 1 144 ? -8.004  58.690  -62.160 1.00 20.08  ? 144 SER D O   1 
ATOM   5856  C  CB  . SER C 1 144 ? -6.844  55.870  -61.892 1.00 27.08  ? 144 SER D CB  1 
ATOM   5857  O  OG  . SER C 1 144 ? -6.221  55.798  -60.620 1.00 19.30  ? 144 SER D OG  1 
ATOM   5858  N  N   . CYS C 1 145 ? -5.911  59.229  -61.597 1.00 17.26  ? 145 CYS D N   1 
ATOM   5859  C  CA  . CYS C 1 145 ? -6.371  60.479  -61.018 1.00 19.45  ? 145 CYS D CA  1 
ATOM   5860  C  C   . CYS C 1 145 ? -7.104  61.303  -62.072 1.00 23.59  ? 145 CYS D C   1 
ATOM   5861  O  O   . CYS C 1 145 ? -6.753  61.284  -63.258 1.00 22.51  ? 145 CYS D O   1 
ATOM   5862  C  CB  . CYS C 1 145 ? -5.203  61.258  -60.421 1.00 23.52  ? 145 CYS D CB  1 
ATOM   5863  S  SG  . CYS C 1 145 ? -4.561  60.415  -58.941 1.00 28.04  ? 145 CYS D SG  1 
ATOM   5864  N  N   . GLY C 1 146 ? -8.175  61.969  -61.638 1.00 16.69  ? 146 GLY D N   1 
ATOM   5865  C  CA  . GLY C 1 146 ? -9.076  62.661  -62.526 1.00 17.84  ? 146 GLY D CA  1 
ATOM   5866  C  C   . GLY C 1 146 ? -10.221 61.828  -63.064 1.00 21.11  ? 146 GLY D C   1 
ATOM   5867  O  O   . GLY C 1 146 ? -11.150 62.390  -63.666 1.00 20.56  ? 146 GLY D O   1 
ATOM   5868  N  N   . SER C 1 147 ? -10.194 60.511  -62.884 1.00 19.24  ? 147 SER D N   1 
ATOM   5869  C  CA  . SER C 1 147 ? -11.385 59.731  -63.173 1.00 18.26  ? 147 SER D CA  1 
ATOM   5870  C  C   . SER C 1 147 ? -12.506 60.195  -62.267 1.00 14.87  ? 147 SER D C   1 
ATOM   5871  O  O   . SER C 1 147 ? -12.271 60.596  -61.128 1.00 20.41  ? 147 SER D O   1 
ATOM   5872  C  CB  . SER C 1 147 ? -11.114 58.247  -62.951 1.00 18.95  ? 147 SER D CB  1 
ATOM   5873  O  OG  . SER C 1 147 ? -10.034 57.829  -63.756 1.00 20.24  ? 147 SER D OG  1 
ATOM   5874  N  N   . VAL C 1 148 ? -13.735 60.156  -62.769 1.00 17.63  ? 148 VAL D N   1 
ATOM   5875  C  CA  . VAL C 1 148 ? -14.840 60.740  -62.019 1.00 18.28  ? 148 VAL D CA  1 
ATOM   5876  C  C   . VAL C 1 148 ? -15.880 59.675  -61.660 1.00 21.58  ? 148 VAL D C   1 
ATOM   5877  O  O   . VAL C 1 148 ? -15.980 58.621  -62.288 1.00 18.08  ? 148 VAL D O   1 
ATOM   5878  C  CB  . VAL C 1 148 ? -15.521 61.884  -62.781 1.00 19.02  ? 148 VAL D CB  1 
ATOM   5879  C  CG1 . VAL C 1 148 ? -14.521 62.999  -63.080 1.00 19.23  ? 148 VAL D CG1 1 
ATOM   5880  C  CG2 . VAL C 1 148 ? -16.234 61.347  -64.026 1.00 17.04  ? 148 VAL D CG2 1 
ATOM   5881  N  N   . GLY C 1 149 ? -16.652 59.977  -60.619 1.00 17.22  ? 149 GLY D N   1 
ATOM   5882  C  CA  . GLY C 1 149 ? -17.821 59.204  -60.246 1.00 17.67  ? 149 GLY D CA  1 
ATOM   5883  C  C   . GLY C 1 149 ? -19.075 60.009  -60.538 1.00 22.30  ? 149 GLY D C   1 
ATOM   5884  O  O   . GLY C 1 149 ? -19.059 61.244  -60.506 1.00 26.41  ? 149 GLY D O   1 
ATOM   5885  N  N   . PHE C 1 150 ? -20.171 59.317  -60.834 1.00 20.33  ? 150 PHE D N   1 
ATOM   5886  C  CA  . PHE C 1 150 ? -21.334 60.014  -61.368 1.00 21.80  ? 150 PHE D CA  1 
ATOM   5887  C  C   . PHE C 1 150 ? -22.583 59.172  -61.151 1.00 22.43  ? 150 PHE D C   1 
ATOM   5888  O  O   . PHE C 1 150 ? -22.519 57.952  -60.997 1.00 20.08  ? 150 PHE D O   1 
ATOM   5889  C  CB  . PHE C 1 150 ? -21.157 60.330  -62.861 1.00 20.08  ? 150 PHE D CB  1 
ATOM   5890  C  CG  . PHE C 1 150 ? -20.988 59.108  -63.736 1.00 17.58  ? 150 PHE D CG  1 
ATOM   5891  C  CD1 . PHE C 1 150 ? -19.756 58.477  -63.850 1.00 19.21  ? 150 PHE D CD1 1 
ATOM   5892  C  CD2 . PHE C 1 150 ? -22.054 58.602  -64.464 1.00 19.06  ? 150 PHE D CD2 1 
ATOM   5893  C  CE1 . PHE C 1 150 ? -19.605 57.337  -64.666 1.00 19.01  ? 150 PHE D CE1 1 
ATOM   5894  C  CE2 . PHE C 1 150 ? -21.916 57.475  -65.280 1.00 16.92  ? 150 PHE D CE2 1 
ATOM   5895  C  CZ  . PHE C 1 150 ? -20.695 56.839  -65.373 1.00 18.53  ? 150 PHE D CZ  1 
ATOM   5896  N  N   . ASN C 1 151 ? -23.715 59.860  -61.138 1.00 19.87  ? 151 ASN D N   1 
ATOM   5897  C  CA  . ASN C 1 151 ? -25.047 59.293  -61.212 1.00 25.81  ? 151 ASN D CA  1 
ATOM   5898  C  C   . ASN C 1 151 ? -25.766 59.870  -62.427 1.00 31.99  ? 151 ASN D C   1 
ATOM   5899  O  O   . ASN C 1 151 ? -25.414 60.941  -62.946 1.00 26.26  ? 151 ASN D O   1 
ATOM   5900  C  CB  . ASN C 1 151 ? -25.862 59.578  -59.922 1.00 27.11  ? 151 ASN D CB  1 
ATOM   5901  C  CG  . ASN C 1 151 ? -25.467 58.656  -58.745 1.00 26.53  ? 151 ASN D CG  1 
ATOM   5902  O  OD1 . ASN C 1 151 ? -24.657 59.001  -57.880 1.00 30.07  ? 151 ASN D OD1 1 
ATOM   5903  N  ND2 . ASN C 1 151 ? -26.044 57.485  -58.729 1.00 20.55  ? 151 ASN D ND2 1 
ATOM   5904  N  N   . ILE C 1 152 ? -26.785 59.153  -62.897 1.00 28.85  ? 152 ILE D N   1 
ATOM   5905  C  CA  . ILE C 1 152 ? -27.593 59.628  -64.012 1.00 34.99  ? 152 ILE D CA  1 
ATOM   5906  C  C   . ILE C 1 152 ? -29.044 59.654  -63.574 1.00 41.91  ? 152 ILE D C   1 
ATOM   5907  O  O   . ILE C 1 152 ? -29.548 58.669  -63.026 1.00 47.40  ? 152 ILE D O   1 
ATOM   5908  C  CB  . ILE C 1 152 ? -27.428 58.754  -65.261 1.00 34.83  ? 152 ILE D CB  1 
ATOM   5909  C  CG1 . ILE C 1 152 ? -25.954 58.409  -65.471 1.00 27.62  ? 152 ILE D CG1 1 
ATOM   5910  C  CG2 . ILE C 1 152 ? -27.988 59.504  -66.469 1.00 33.28  ? 152 ILE D CG2 1 
ATOM   5911  C  CD1 . ILE C 1 152 ? -25.649 57.736  -66.808 1.00 34.15  ? 152 ILE D CD1 1 
ATOM   5912  N  N   . ASP C 1 153 ? -29.700 60.789  -63.777 1.00 42.25  ? 153 ASP D N   1 
ATOM   5913  C  CA  . ASP C 1 153 ? -31.129 60.928  -63.529 1.00 49.09  ? 153 ASP D CA  1 
ATOM   5914  C  C   . ASP C 1 153 ? -31.775 61.433  -64.818 1.00 50.46  ? 153 ASP D C   1 
ATOM   5915  O  O   . ASP C 1 153 ? -31.510 62.565  -65.247 1.00 46.17  ? 153 ASP D O   1 
ATOM   5916  C  CB  . ASP C 1 153 ? -31.389 61.864  -62.352 1.00 45.83  ? 153 ASP D CB  1 
ATOM   5917  C  CG  . ASP C 1 153 ? -32.837 61.869  -61.926 1.00 54.99  ? 153 ASP D CG  1 
ATOM   5918  O  OD1 . ASP C 1 153 ? -33.294 60.818  -61.421 1.00 57.03  ? 153 ASP D OD1 1 
ATOM   5919  O  OD2 . ASP C 1 153 ? -33.516 62.906  -62.097 1.00 54.63  ? 153 ASP D OD2 1 
ATOM   5920  N  N   . TYR C 1 154 ? -32.588 60.577  -65.447 1.00 48.92  ? 154 TYR D N   1 
ATOM   5921  C  CA  . TYR C 1 154 ? -33.220 60.851  -66.735 1.00 46.77  ? 154 TYR D CA  1 
ATOM   5922  C  C   . TYR C 1 154 ? -32.158 61.080  -67.796 1.00 55.45  ? 154 TYR D C   1 
ATOM   5923  O  O   . TYR C 1 154 ? -31.637 60.122  -68.369 1.00 62.26  ? 154 TYR D O   1 
ATOM   5924  C  CB  . TYR C 1 154 ? -34.189 62.029  -66.636 1.00 43.84  ? 154 TYR D CB  1 
ATOM   5925  C  CG  . TYR C 1 154 ? -35.281 61.797  -65.618 0.00 45.21  ? 154 TYR D CG  1 
ATOM   5926  C  CD1 . TYR C 1 154 ? -36.250 60.825  -65.828 0.00 42.85  ? 154 TYR D CD1 1 
ATOM   5927  C  CD2 . TYR C 1 154 ? -35.328 62.526  -64.441 0.00 45.02  ? 154 TYR D CD2 1 
ATOM   5928  C  CE1 . TYR C 1 154 ? -37.249 60.601  -64.902 0.00 42.07  ? 154 TYR D CE1 1 
ATOM   5929  C  CE2 . TYR C 1 154 ? -36.322 62.307  -63.505 0.00 44.72  ? 154 TYR D CE2 1 
ATOM   5930  C  CZ  . TYR C 1 154 ? -37.280 61.344  -63.742 0.00 43.68  ? 154 TYR D CZ  1 
ATOM   5931  O  OH  . TYR C 1 154 ? -38.272 61.122  -62.815 0.00 44.11  ? 154 TYR D OH  1 
ATOM   5932  N  N   . ASP C 1 155 ? -31.821 62.330  -68.071 1.00 52.09  ? 155 ASP D N   1 
ATOM   5933  C  CA  . ASP C 1 155 ? -30.768 62.612  -69.029 1.00 47.68  ? 155 ASP D CA  1 
ATOM   5934  C  C   . ASP C 1 155 ? -29.582 63.324  -68.404 1.00 42.43  ? 155 ASP D C   1 
ATOM   5935  O  O   . ASP C 1 155 ? -28.548 63.455  -69.061 1.00 41.85  ? 155 ASP D O   1 
ATOM   5936  C  CB  . ASP C 1 155 ? -31.318 63.465  -70.185 1.00 58.92  ? 155 ASP D CB  1 
ATOM   5937  C  CG  . ASP C 1 155 ? -32.091 64.699  -69.695 1.00 65.95  ? 155 ASP D CG  1 
ATOM   5938  O  OD1 . ASP C 1 155 ? -32.543 64.714  -68.525 1.00 61.70  ? 155 ASP D OD1 1 
ATOM   5939  O  OD2 . ASP C 1 155 ? -32.224 65.669  -70.477 1.00 62.48  ? 155 ASP D OD2 1 
ATOM   5940  N  N   . CYS C 1 156 ? -29.678 63.710  -67.134 1.00 46.90  ? 156 CYS D N   1 
ATOM   5941  C  CA  . CYS C 1 156 ? -28.695 64.555  -66.469 1.00 34.62  ? 156 CYS D CA  1 
ATOM   5942  C  C   . CYS C 1 156 ? -27.664 63.747  -65.689 1.00 37.47  ? 156 CYS D C   1 
ATOM   5943  O  O   . CYS C 1 156 ? -28.022 62.873  -64.887 1.00 32.43  ? 156 CYS D O   1 
ATOM   5944  C  CB  . CYS C 1 156 ? -29.405 65.507  -65.526 1.00 31.40  ? 156 CYS D CB  1 
ATOM   5945  S  SG  . CYS C 1 156 ? -28.309 66.680  -64.799 1.00 34.33  ? 156 CYS D SG  1 
ATOM   5946  N  N   . VAL C 1 157 ? -26.387 64.056  -65.925 1.00 34.41  ? 157 VAL D N   1 
ATOM   5947  C  CA  . VAL C 1 157 ? -25.271 63.448  -65.208 1.00 27.81  ? 157 VAL D CA  1 
ATOM   5948  C  C   . VAL C 1 157 ? -24.942 64.317  -64.004 1.00 28.84  ? 157 VAL D C   1 
ATOM   5949  O  O   . VAL C 1 157 ? -24.674 65.512  -64.152 1.00 32.60  ? 157 VAL D O   1 
ATOM   5950  C  CB  . VAL C 1 157 ? -24.041 63.293  -66.116 1.00 25.54  ? 157 VAL D CB  1 
ATOM   5951  C  CG1 . VAL C 1 157 ? -22.893 62.650  -65.342 1.00 24.10  ? 157 VAL D CG1 1 
ATOM   5952  C  CG2 . VAL C 1 157 ? -24.378 62.482  -67.369 1.00 23.41  ? 157 VAL D CG2 1 
ATOM   5953  N  N   . SER C 1 158 ? -24.974 63.727  -62.814 1.00 28.73  ? 158 SER D N   1 
ATOM   5954  C  CA  . SER C 1 158 ? -24.573 64.399  -61.580 1.00 21.50  ? 158 SER D CA  1 
ATOM   5955  C  C   . SER C 1 158 ? -23.180 63.905  -61.224 1.00 24.25  ? 158 SER D C   1 
ATOM   5956  O  O   . SER C 1 158 ? -23.007 62.772  -60.768 1.00 25.87  ? 158 SER D O   1 
ATOM   5957  C  CB  . SER C 1 158 ? -25.558 64.121  -60.455 1.00 27.26  ? 158 SER D CB  1 
ATOM   5958  O  OG  . SER C 1 158 ? -26.754 64.837  -60.674 1.00 36.64  ? 158 SER D OG  1 
ATOM   5959  N  N   . PHE C 1 159 ? -22.187 64.747  -61.456 1.00 23.72  ? 159 PHE D N   1 
ATOM   5960  C  CA  . PHE C 1 159 ? -20.810 64.429  -61.109 1.00 25.10  ? 159 PHE D CA  1 
ATOM   5961  C  C   . PHE C 1 159 ? -20.628 64.642  -59.614 1.00 20.88  ? 159 PHE D C   1 
ATOM   5962  O  O   . PHE C 1 159 ? -20.885 65.741  -59.111 1.00 20.38  ? 159 PHE D O   1 
ATOM   5963  C  CB  . PHE C 1 159 ? -19.828 65.302  -61.911 1.00 22.17  ? 159 PHE D CB  1 
ATOM   5964  C  CG  . PHE C 1 159 ? -19.845 65.021  -63.399 1.00 20.18  ? 159 PHE D CG  1 
ATOM   5965  C  CD1 . PHE C 1 159 ? -19.205 63.902  -63.909 1.00 16.03  ? 159 PHE D CD1 1 
ATOM   5966  C  CD2 . PHE C 1 159 ? -20.534 65.864  -64.278 1.00 21.36  ? 159 PHE D CD2 1 
ATOM   5967  C  CE1 . PHE C 1 159 ? -19.231 63.636  -65.264 1.00 19.22  ? 159 PHE D CE1 1 
ATOM   5968  C  CE2 . PHE C 1 159 ? -20.570 65.614  -65.632 1.00 17.82  ? 159 PHE D CE2 1 
ATOM   5969  C  CZ  . PHE C 1 159 ? -19.915 64.491  -66.134 1.00 22.04  ? 159 PHE D CZ  1 
ATOM   5970  N  N   . CYS C 1 160 ? -20.168 63.602  -58.909 1.00 19.31  ? 160 CYS D N   1 
ATOM   5971  C  CA  . CYS C 1 160 ? -19.996 63.697  -57.473 1.00 22.05  ? 160 CYS D CA  1 
ATOM   5972  C  C   . CYS C 1 160 ? -18.570 63.457  -56.992 1.00 23.40  ? 160 CYS D C   1 
ATOM   5973  O  O   . CYS C 1 160 ? -18.277 63.751  -55.824 1.00 26.05  ? 160 CYS D O   1 
ATOM   5974  C  CB  . CYS C 1 160 ? -20.940 62.717  -56.752 1.00 25.99  ? 160 CYS D CB  1 
ATOM   5975  S  SG  . CYS C 1 160 ? -20.725 60.955  -57.124 1.00 30.48  ? 160 CYS D SG  1 
ATOM   5976  N  N   . TYR C 1 161 ? -17.681 62.928  -57.830 1.00 18.77  ? 161 TYR D N   1 
ATOM   5977  C  CA  . TYR C 1 161 ? -16.397 62.453  -57.337 1.00 19.82  ? 161 TYR D CA  1 
ATOM   5978  C  C   . TYR C 1 161 ? -15.347 62.598  -58.416 1.00 21.55  ? 161 TYR D C   1 
ATOM   5979  O  O   . TYR C 1 161 ? -15.619 62.315  -59.583 1.00 24.95  ? 161 TYR D O   1 
ATOM   5980  C  CB  . TYR C 1 161 ? -16.463 60.977  -56.908 1.00 16.31  ? 161 TYR D CB  1 
ATOM   5981  C  CG  . TYR C 1 161 ? -15.149 60.393  -56.428 1.00 17.14  ? 161 TYR D CG  1 
ATOM   5982  C  CD1 . TYR C 1 161 ? -14.751 60.542  -55.105 1.00 17.15  ? 161 TYR D CD1 1 
ATOM   5983  C  CD2 . TYR C 1 161 ? -14.329 59.652  -57.280 1.00 20.65  ? 161 TYR D CD2 1 
ATOM   5984  C  CE1 . TYR C 1 161 ? -13.566 60.007  -54.637 1.00 17.63  ? 161 TYR D CE1 1 
ATOM   5985  C  CE2 . TYR C 1 161 ? -13.136 59.081  -56.815 1.00 19.53  ? 161 TYR D CE2 1 
ATOM   5986  C  CZ  . TYR C 1 161 ? -12.756 59.268  -55.479 1.00 21.99  ? 161 TYR D CZ  1 
ATOM   5987  O  OH  . TYR C 1 161 ? -11.573 58.738  -54.975 1.00 16.98  ? 161 TYR D OH  1 
ATOM   5988  N  N   . MET C 1 162 ? -14.151 63.025  -58.019 1.00 19.49  ? 162 MET D N   1 
ATOM   5989  C  CA  . MET C 1 162 ? -12.980 62.977  -58.882 1.00 20.10  ? 162 MET D CA  1 
ATOM   5990  C  C   . MET C 1 162 ? -11.856 62.351  -58.088 1.00 21.17  ? 162 MET D C   1 
ATOM   5991  O  O   . MET C 1 162 ? -11.635 62.730  -56.940 1.00 23.70  ? 162 MET D O   1 
ATOM   5992  C  CB  . MET C 1 162 ? -12.573 64.361  -59.378 1.00 18.67  ? 162 MET D CB  1 
ATOM   5993  C  CG  . MET C 1 162 ? -11.273 64.341  -60.134 1.00 21.46  ? 162 MET D CG  1 
ATOM   5994  S  SD  . MET C 1 162 ? -10.893 65.978  -60.749 1.00 28.99  ? 162 MET D SD  1 
ATOM   5995  C  CE  . MET C 1 162 ? -11.894 65.960  -62.242 1.00 21.29  ? 162 MET D CE  1 
ATOM   5996  N  N   . HIS C 1 163 ? -11.164 61.385  -58.684 1.00 20.04  ? 163 HIS D N   1 
ATOM   5997  C  CA  . HIS C 1 163 ? -10.235 60.556  -57.924 1.00 20.25  ? 163 HIS D CA  1 
ATOM   5998  C  C   . HIS C 1 163 ? -8.912  61.258  -57.649 1.00 22.70  ? 163 HIS D C   1 
ATOM   5999  O  O   . HIS C 1 163 ? -8.340  61.914  -58.533 1.00 19.42  ? 163 HIS D O   1 
ATOM   6000  C  CB  . HIS C 1 163 ? -9.958  59.253  -58.669 1.00 22.80  ? 163 HIS D CB  1 
ATOM   6001  C  CG  . HIS C 1 163 ? -9.066  58.323  -57.908 1.00 22.88  ? 163 HIS D CG  1 
ATOM   6002  N  ND1 . HIS C 1 163 ? -9.381  57.860  -56.649 1.00 22.90  ? 163 HIS D ND1 1 
ATOM   6003  C  CD2 . HIS C 1 163 ? -7.860  57.792  -58.215 1.00 19.74  ? 163 HIS D CD2 1 
ATOM   6004  C  CE1 . HIS C 1 163 ? -8.407  57.077  -56.218 1.00 27.33  ? 163 HIS D CE1 1 
ATOM   6005  N  NE2 . HIS C 1 163 ? -7.473  57.020  -57.149 1.00 20.43  ? 163 HIS D NE2 1 
ATOM   6006  N  N   . HIS C 1 164 ? -8.387  61.062  -56.424 1.00 20.27  ? 164 HIS D N   1 
ATOM   6007  C  CA  . HIS C 1 164 ? -7.124  61.726  -56.079 1.00 26.08  ? 164 HIS D CA  1 
ATOM   6008  C  C   . HIS C 1 164 ? -6.043  60.814  -55.503 1.00 25.89  ? 164 HIS D C   1 
ATOM   6009  O  O   . HIS C 1 164 ? -4.861  61.035  -55.803 1.00 22.71  ? 164 HIS D O   1 
ATOM   6010  C  CB  . HIS C 1 164 ? -7.364  62.878  -55.089 1.00 26.28  ? 164 HIS D CB  1 
ATOM   6011  C  CG  . HIS C 1 164 ? -7.782  64.151  -55.744 1.00 21.56  ? 164 HIS D CG  1 
ATOM   6012  N  ND1 . HIS C 1 164 ? -9.026  64.316  -56.312 1.00 21.73  ? 164 HIS D ND1 1 
ATOM   6013  C  CD2 . HIS C 1 164 ? -7.133  65.325  -55.904 1.00 23.05  ? 164 HIS D CD2 1 
ATOM   6014  C  CE1 . HIS C 1 164 ? -9.120  65.539  -56.809 1.00 23.15  ? 164 HIS D CE1 1 
ATOM   6015  N  NE2 . HIS C 1 164 ? -7.988  66.174  -56.570 1.00 23.64  ? 164 HIS D NE2 1 
ATOM   6016  N  N   . MET C 1 165 ? -6.437  59.964  -54.564 1.00 18.54  ? 165 MET D N   1 
ATOM   6017  C  CA  . MET C 1 165 ? -5.385  59.253  -53.823 1.00 25.10  ? 165 MET D CA  1 
ATOM   6018  C  C   . MET C 1 165 ? -5.734  57.853  -53.349 1.00 25.24  ? 165 MET D C   1 
ATOM   6019  O  O   . MET C 1 165 ? -6.902  57.476  -53.355 1.00 27.54  ? 165 MET D O   1 
ATOM   6020  C  CB  . MET C 1 165 ? -4.999  60.072  -52.587 1.00 27.79  ? 165 MET D CB  1 
ATOM   6021  C  CG  . MET C 1 165 ? -6.147  60.641  -51.807 1.00 27.62  ? 165 MET D CG  1 
ATOM   6022  S  SD  . MET C 1 165 ? -5.546  61.537  -50.372 1.00 33.36  ? 165 MET D SD  1 
ATOM   6023  C  CE  . MET C 1 165 ? -4.503  60.294  -49.618 1.00 36.52  ? 165 MET D CE  1 
ATOM   6024  N  N   . GLU C 1 166 ? -4.697  57.164  -52.904 1.00 28.29  ? 166 GLU D N   1 
ATOM   6025  C  CA  . GLU C 1 166 ? -4.830  55.795  -52.392 1.00 28.95  ? 166 GLU D CA  1 
ATOM   6026  C  C   . GLU C 1 166 ? -4.422  55.834  -50.926 1.00 28.88  ? 166 GLU D C   1 
ATOM   6027  O  O   . GLU C 1 166 ? -3.479  56.542  -50.591 1.00 31.05  ? 166 GLU D O   1 
ATOM   6028  C  CB  . GLU C 1 166 ? -3.960  54.894  -53.258 1.00 30.86  ? 166 GLU D CB  1 
ATOM   6029  C  CG  . GLU C 1 166 ? -4.019  53.424  -52.919 1.00 39.48  ? 166 GLU D CG  1 
ATOM   6030  C  CD  . GLU C 1 166 ? -2.981  52.671  -53.728 1.00 53.48  ? 166 GLU D CD  1 
ATOM   6031  O  OE1 . GLU C 1 166 ? -3.298  52.284  -54.856 1.00 52.19  ? 166 GLU D OE1 1 
ATOM   6032  O  OE2 . GLU C 1 166 ? -1.847  52.517  -53.245 1.00 56.19  ? 166 GLU D OE2 1 
ATOM   6033  N  N   . LEU C 1 167 ? -5.155  55.116  -50.096 1.00 32.49  ? 167 LEU D N   1 
ATOM   6034  C  CA  . LEU C 1 167 ? -4.904  55.104  -48.643 1.00 29.58  ? 167 LEU D CA  1 
ATOM   6035  C  C   . LEU C 1 167 ? -4.373  53.734  -48.196 1.00 36.07  ? 167 LEU D C   1 
ATOM   6036  O  O   . LEU C 1 167 ? -4.496  52.772  -48.967 1.00 28.25  ? 167 LEU D O   1 
ATOM   6037  C  CB  . LEU C 1 167 ? -6.229  55.466  -47.988 1.00 25.85  ? 167 LEU D CB  1 
ATOM   6038  C  CG  . LEU C 1 167 ? -6.558  56.951  -48.021 1.00 33.93  ? 167 LEU D CG  1 
ATOM   6039  C  CD1 . LEU C 1 167 ? -8.057  57.155  -48.034 1.00 29.67  ? 167 LEU D CD1 1 
ATOM   6040  C  CD2 . LEU C 1 167 ? -5.926  57.661  -46.841 1.00 32.91  ? 167 LEU D CD2 1 
ATOM   6041  N  N   . PRO C 1 168 ? -3.773  53.609  -46.990 1.00 32.95  ? 168 PRO D N   1 
ATOM   6042  C  CA  . PRO C 1 168 ? -3.136  52.358  -46.556 1.00 37.45  ? 168 PRO D CA  1 
ATOM   6043  C  C   . PRO C 1 168 ? -3.920  51.047  -46.687 1.00 34.75  ? 168 PRO D C   1 
ATOM   6044  O  O   . PRO C 1 168 ? -3.282  50.073  -46.943 1.00 38.51  ? 168 PRO D O   1 
ATOM   6045  C  CB  . PRO C 1 168 ? -2.840  52.650  -45.083 1.00 35.04  ? 168 PRO D CB  1 
ATOM   6046  C  CG  . PRO C 1 168 ? -2.551  54.112  -45.067 1.00 35.87  ? 168 PRO D CG  1 
ATOM   6047  C  CD  . PRO C 1 168 ? -3.609  54.661  -45.991 1.00 34.63  ? 168 PRO D CD  1 
ATOM   6048  N  N   . THR C 1 169 ? -5.244  51.050  -46.551 1.00 32.23  ? 169 THR D N   1 
ATOM   6049  C  CA  . THR C 1 169 ? -5.936  49.761  -46.580 1.00 42.17  ? 169 THR D CA  1 
ATOM   6050  C  C   . THR C 1 169 ? -6.443  49.381  -47.972 1.00 43.85  ? 169 THR D C   1 
ATOM   6051  O  O   . THR C 1 169 ? -7.251  48.452  -48.099 1.00 40.56  ? 169 THR D O   1 
ATOM   6052  C  CB  . THR C 1 169 ? -7.102  49.743  -45.582 1.00 40.19  ? 169 THR D CB  1 
ATOM   6053  O  OG1 . THR C 1 169 ? -8.003  50.827  -45.861 1.00 48.39  ? 169 THR D OG1 1 
ATOM   6054  C  CG2 . THR C 1 169 ? -6.585  49.845  -44.122 1.00 40.13  ? 169 THR D CG2 1 
ATOM   6055  N  N   . GLY C 1 170 ? -5.929  50.016  -49.017 1.00 38.33  ? 170 GLY D N   1 
ATOM   6056  C  CA  . GLY C 1 170 ? -6.427  49.758  -50.349 1.00 29.73  ? 170 GLY D CA  1 
ATOM   6057  C  C   . GLY C 1 170 ? -7.749  50.419  -50.652 1.00 33.70  ? 170 GLY D C   1 
ATOM   6058  O  O   . GLY C 1 170 ? -8.491  49.935  -51.517 1.00 34.84  ? 170 GLY D O   1 
ATOM   6059  N  N   . VAL C 1 171 ? -8.090  51.499  -49.951 1.00 27.00  ? 171 VAL D N   1 
ATOM   6060  C  CA  . VAL C 1 171 ? -9.294  52.240  -50.286 1.00 19.61  ? 171 VAL D CA  1 
ATOM   6061  C  C   . VAL C 1 171 ? -8.853  53.593  -50.830 1.00 29.33  ? 171 VAL D C   1 
ATOM   6062  O  O   . VAL C 1 171 ? -7.649  53.883  -50.897 1.00 24.93  ? 171 VAL D O   1 
ATOM   6063  C  CB  . VAL C 1 171 ? -10.240 52.355  -49.081 1.00 28.72  ? 171 VAL D CB  1 
ATOM   6064  C  CG1 . VAL C 1 171 ? -10.639 50.926  -48.607 1.00 29.66  ? 171 VAL D CG1 1 
ATOM   6065  C  CG2 . VAL C 1 171 ? -9.608  53.179  -47.955 1.00 22.63  ? 171 VAL D CG2 1 
ATOM   6066  N  N   . HIS C 1 172 ? -9.810  54.419  -51.261 1.00 24.61  ? 172 HIS D N   1 
ATOM   6067  C  CA  . HIS C 1 172 ? -9.477  55.531  -52.131 1.00 23.27  ? 172 HIS D CA  1 
ATOM   6068  C  C   . HIS C 1 172 ? -10.187 56.797  -51.666 1.00 28.33  ? 172 HIS D C   1 
ATOM   6069  O  O   . HIS C 1 172 ? -11.247 56.736  -51.032 1.00 25.37  ? 172 HIS D O   1 
ATOM   6070  C  CB  . HIS C 1 172 ? -9.823  55.174  -53.575 1.00 26.98  ? 172 HIS D CB  1 
ATOM   6071  C  CG  . HIS C 1 172 ? -9.134  53.934  -54.068 1.00 28.63  ? 172 HIS D CG  1 
ATOM   6072  N  ND1 . HIS C 1 172 ? -9.786  52.727  -54.210 1.00 26.41  ? 172 HIS D ND1 1 
ATOM   6073  C  CD2 . HIS C 1 172 ? -7.845  53.707  -54.419 1.00 28.01  ? 172 HIS D CD2 1 
ATOM   6074  C  CE1 . HIS C 1 172 ? -8.934  51.818  -54.654 1.00 26.05  ? 172 HIS D CE1 1 
ATOM   6075  N  NE2 . HIS C 1 172 ? -7.745  52.379  -54.769 1.00 27.50  ? 172 HIS D NE2 1 
ATOM   6076  N  N   . ALA C 1 173 ? -9.599  57.951  -51.998 1.00 23.46  ? 173 ALA D N   1 
ATOM   6077  C  CA  . ALA C 1 173 ? -10.096 59.233  -51.511 1.00 22.28  ? 173 ALA D CA  1 
ATOM   6078  C  C   . ALA C 1 173 ? -10.079 60.269  -52.636 1.00 26.23  ? 173 ALA D C   1 
ATOM   6079  O  O   . ALA C 1 173 ? -9.221  60.238  -53.526 1.00 23.61  ? 173 ALA D O   1 
ATOM   6080  C  CB  . ALA C 1 173 ? -9.280  59.714  -50.300 1.00 21.51  ? 173 ALA D CB  1 
ATOM   6081  N  N   . GLY C 1 174 ? -11.057 61.168  -52.617 1.00 20.70  ? 174 GLY D N   1 
ATOM   6082  C  CA  . GLY C 1 174 ? -11.113 62.164  -53.657 1.00 20.66  ? 174 GLY D CA  1 
ATOM   6083  C  C   . GLY C 1 174 ? -11.935 63.370  -53.263 1.00 22.77  ? 174 GLY D C   1 
ATOM   6084  O  O   . GLY C 1 174 ? -12.271 63.568  -52.093 1.00 20.58  ? 174 GLY D O   1 
ATOM   6085  N  N   . THR C 1 175 ? -12.231 64.196  -54.263 1.00 19.19  ? 175 THR D N   1 
ATOM   6086  C  CA  . THR C 1 175 ? -12.976 65.420  -54.059 1.00 19.32  ? 175 THR D CA  1 
ATOM   6087  C  C   . THR C 1 175 ? -14.274 65.388  -54.843 1.00 20.36  ? 175 THR D C   1 
ATOM   6088  O  O   . THR C 1 175 ? -14.431 64.640  -55.816 1.00 20.82  ? 175 THR D O   1 
ATOM   6089  C  CB  . THR C 1 175 ? -12.171 66.650  -54.513 1.00 20.78  ? 175 THR D CB  1 
ATOM   6090  O  OG1 . THR C 1 175 ? -12.018 66.622  -55.948 1.00 20.60  ? 175 THR D OG1 1 
ATOM   6091  C  CG2 . THR C 1 175 ? -10.812 66.632  -53.882 1.00 18.78  ? 175 THR D CG2 1 
ATOM   6092  N  N   . ASP C 1 176 ? -15.163 66.297  -54.477 1.00 18.85  ? 176 ASP D N   1 
ATOM   6093  C  CA  . ASP C 1 176 ? -16.254 66.637  -55.364 1.00 20.63  ? 176 ASP D CA  1 
ATOM   6094  C  C   . ASP C 1 176 ? -15.713 67.459  -56.535 1.00 21.23  ? 176 ASP D C   1 
ATOM   6095  O  O   . ASP C 1 176 ? -14.506 67.653  -56.698 1.00 20.76  ? 176 ASP D O   1 
ATOM   6096  C  CB  . ASP C 1 176 ? -17.346 67.389  -54.601 1.00 23.35  ? 176 ASP D CB  1 
ATOM   6097  C  CG  . ASP C 1 176 ? -16.857 68.716  -53.991 1.00 24.67  ? 176 ASP D CG  1 
ATOM   6098  O  OD1 . ASP C 1 176 ? -15.869 69.330  -54.469 1.00 23.38  ? 176 ASP D OD1 1 
ATOM   6099  O  OD2 . ASP C 1 176 ? -17.508 69.171  -53.029 1.00 27.05  ? 176 ASP D OD2 1 
ATOM   6100  N  N   . LEU C 1 177 ? -16.617 67.936  -57.385 1.00 23.33  ? 177 LEU D N   1 
ATOM   6101  C  CA  . LEU C 1 177 ? -16.165 68.656  -58.561 1.00 19.24  ? 177 LEU D CA  1 
ATOM   6102  C  C   . LEU C 1 177 ? -15.902 70.119  -58.290 1.00 23.01  ? 177 LEU D C   1 
ATOM   6103  O  O   . LEU C 1 177 ? -15.487 70.820  -59.210 1.00 27.63  ? 177 LEU D O   1 
ATOM   6104  C  CB  . LEU C 1 177 ? -17.156 68.490  -59.712 1.00 19.72  ? 177 LEU D CB  1 
ATOM   6105  C  CG  . LEU C 1 177 ? -16.793 67.356  -60.670 1.00 20.88  ? 177 LEU D CG  1 
ATOM   6106  C  CD1 . LEU C 1 177 ? -15.504 67.722  -61.382 1.00 19.26  ? 177 LEU D CD1 1 
ATOM   6107  C  CD2 . LEU C 1 177 ? -16.617 66.026  -59.922 1.00 22.71  ? 177 LEU D CD2 1 
ATOM   6108  N  N   . GLU C 1 178 ? -16.116 70.595  -57.067 1.00 23.07  ? 178 GLU D N   1 
ATOM   6109  C  CA  . GLU C 1 178 ? -15.597 71.893  -56.650 1.00 25.98  ? 178 GLU D CA  1 
ATOM   6110  C  C   . GLU C 1 178 ? -14.245 71.799  -55.980 1.00 27.56  ? 178 GLU D C   1 
ATOM   6111  O  O   . GLU C 1 178 ? -13.751 72.820  -55.492 1.00 27.92  ? 178 GLU D O   1 
ATOM   6112  C  CB  . GLU C 1 178 ? -16.582 72.591  -55.718 1.00 25.46  ? 178 GLU D CB  1 
ATOM   6113  C  CG  . GLU C 1 178 ? -17.956 72.363  -56.243 1.00 33.16  ? 178 GLU D CG  1 
ATOM   6114  C  CD  . GLU C 1 178 ? -18.545 73.584  -56.887 1.00 34.04  ? 178 GLU D CD  1 
ATOM   6115  O  OE1 . GLU C 1 178 ? -17.775 74.500  -57.272 1.00 39.21  ? 178 GLU D OE1 1 
ATOM   6116  O  OE2 . GLU C 1 178 ? -19.771 73.567  -57.113 1.00 37.26  ? 178 GLU D OE2 1 
ATOM   6117  N  N   . GLY C 1 179 ? -13.669 70.598  -55.901 1.00 24.89  ? 179 GLY D N   1 
ATOM   6118  C  CA  . GLY C 1 179 ? -12.338 70.397  -55.379 1.00 23.66  ? 179 GLY D CA  1 
ATOM   6119  C  C   . GLY C 1 179 ? -12.216 70.227  -53.889 1.00 20.21  ? 179 GLY D C   1 
ATOM   6120  O  O   . GLY C 1 179 ? -11.093 70.155  -53.388 1.00 20.21  ? 179 GLY D O   1 
ATOM   6121  N  N   . ASN C 1 180 ? -13.317 70.071  -53.170 1.00 25.26  ? 180 ASN D N   1 
ATOM   6122  C  CA  . ASN C 1 180 ? -13.252 69.829  -51.731 1.00 21.62  ? 180 ASN D CA  1 
ATOM   6123  C  C   . ASN C 1 180 ? -13.244 68.322  -51.468 1.00 20.06  ? 180 ASN D C   1 
ATOM   6124  O  O   . ASN C 1 180 ? -14.162 67.598  -51.877 1.00 20.29  ? 180 ASN D O   1 
ATOM   6125  C  CB  . ASN C 1 180 ? -14.417 70.503  -51.011 1.00 23.38  ? 180 ASN D CB  1 
ATOM   6126  C  CG  . ASN C 1 180 ? -14.466 71.991  -51.277 1.00 21.87  ? 180 ASN D CG  1 
ATOM   6127  O  OD1 . ASN C 1 180 ? -13.542 72.711  -50.921 1.00 23.88  ? 180 ASN D OD1 1 
ATOM   6128  N  ND2 . ASN C 1 180 ? -15.556 72.462  -51.850 1.00 21.04  ? 180 ASN D ND2 1 
ATOM   6129  N  N   . PHE C 1 181 ? -12.199 67.857  -50.800 1.00 21.05  ? 181 PHE D N   1 
ATOM   6130  C  CA  . PHE C 1 181 ? -12.075 66.446  -50.465 1.00 20.12  ? 181 PHE D CA  1 
ATOM   6131  C  C   . PHE C 1 181 ? -13.276 65.951  -49.683 1.00 22.06  ? 181 PHE D C   1 
ATOM   6132  O  O   . PHE C 1 181 ? -13.819 66.663  -48.836 1.00 22.30  ? 181 PHE D O   1 
ATOM   6133  C  CB  . PHE C 1 181 ? -10.828 66.223  -49.622 1.00 20.05  ? 181 PHE D CB  1 
ATOM   6134  C  CG  . PHE C 1 181 ? -9.652  65.768  -50.396 1.00 21.44  ? 181 PHE D CG  1 
ATOM   6135  C  CD1 . PHE C 1 181 ? -9.481  64.428  -50.677 1.00 22.61  ? 181 PHE D CD1 1 
ATOM   6136  C  CD2 . PHE C 1 181 ? -8.718  66.676  -50.863 1.00 22.72  ? 181 PHE D CD2 1 
ATOM   6137  C  CE1 . PHE C 1 181 ? -8.395  63.985  -51.392 1.00 22.09  ? 181 PHE D CE1 1 
ATOM   6138  C  CE2 . PHE C 1 181 ? -7.632  66.234  -51.589 1.00 25.57  ? 181 PHE D CE2 1 
ATOM   6139  C  CZ  . PHE C 1 181 ? -7.479  64.870  -51.846 1.00 21.23  ? 181 PHE D CZ  1 
ATOM   6140  N  N   . TYR C 1 182 ? -13.680 64.714  -49.955 1.00 19.91  ? 182 TYR D N   1 
ATOM   6141  C  CA  . TYR C 1 182 ? -14.518 63.999  -49.010 1.00 21.53  ? 182 TYR D CA  1 
ATOM   6142  C  C   . TYR C 1 182 ? -13.619 63.521  -47.873 1.00 23.69  ? 182 TYR D C   1 
ATOM   6143  O  O   . TYR C 1 182 ? -12.668 62.767  -48.102 1.00 20.77  ? 182 TYR D O   1 
ATOM   6144  C  CB  . TYR C 1 182 ? -15.227 62.817  -49.677 1.00 18.74  ? 182 TYR D CB  1 
ATOM   6145  C  CG  . TYR C 1 182 ? -16.245 63.228  -50.714 1.00 22.94  ? 182 TYR D CG  1 
ATOM   6146  C  CD1 . TYR C 1 182 ? -17.502 63.708  -50.334 1.00 21.63  ? 182 TYR D CD1 1 
ATOM   6147  C  CD2 . TYR C 1 182 ? -15.960 63.137  -52.078 1.00 23.43  ? 182 TYR D CD2 1 
ATOM   6148  C  CE1 . TYR C 1 182 ? -18.438 64.079  -51.280 1.00 25.08  ? 182 TYR D CE1 1 
ATOM   6149  C  CE2 . TYR C 1 182 ? -16.897 63.505  -53.034 1.00 17.85  ? 182 TYR D CE2 1 
ATOM   6150  C  CZ  . TYR C 1 182 ? -18.134 63.976  -52.630 1.00 23.33  ? 182 TYR D CZ  1 
ATOM   6151  O  OH  . TYR C 1 182 ? -19.089 64.341  -53.567 1.00 21.56  ? 182 TYR D OH  1 
ATOM   6152  N  N   . GLY C 1 183 ? -13.887 63.997  -46.661 1.00 21.96  ? 183 GLY D N   1 
ATOM   6153  C  CA  . GLY C 1 183 ? -13.179 63.532  -45.491 1.00 22.56  ? 183 GLY D CA  1 
ATOM   6154  C  C   . GLY C 1 183 ? -11.895 64.264  -45.158 1.00 27.38  ? 183 GLY D C   1 
ATOM   6155  O  O   . GLY C 1 183 ? -11.483 65.220  -45.832 1.00 22.95  ? 183 GLY D O   1 
ATOM   6156  N  N   . PRO C 1 184 ? -11.202 63.779  -44.079 1.00 31.41  ? 184 PRO D N   1 
ATOM   6157  C  CA  . PRO C 1 184 ? -10.008 64.431  -43.528 1.00 26.45  ? 184 PRO D CA  1 
ATOM   6158  C  C   . PRO C 1 184 ? -8.737  64.103  -44.307 1.00 28.98  ? 184 PRO D C   1 
ATOM   6159  O  O   . PRO C 1 184 ? -7.738  63.642  -43.746 1.00 29.91  ? 184 PRO D O   1 
ATOM   6160  C  CB  . PRO C 1 184 ? -9.937  63.855  -42.109 1.00 25.49  ? 184 PRO D CB  1 
ATOM   6161  C  CG  . PRO C 1 184 ? -10.440 62.455  -42.304 1.00 25.91  ? 184 PRO D CG  1 
ATOM   6162  C  CD  . PRO C 1 184 ? -11.481 62.495  -43.413 1.00 27.60  ? 184 PRO D CD  1 
ATOM   6163  N  N   . PHE C 1 185 ? -8.777  64.326  -45.612 1.00 26.96  ? 185 PHE D N   1 
ATOM   6164  C  CA  . PHE C 1 185 ? -7.654  63.997  -46.472 1.00 28.11  ? 185 PHE D CA  1 
ATOM   6165  C  C   . PHE C 1 185 ? -7.139  65.266  -47.134 1.00 26.10  ? 185 PHE D C   1 
ATOM   6166  O  O   . PHE C 1 185 ? -7.858  66.261  -47.261 1.00 30.00  ? 185 PHE D O   1 
ATOM   6167  C  CB  . PHE C 1 185 ? -8.059  62.922  -47.485 1.00 25.65  ? 185 PHE D CB  1 
ATOM   6168  C  CG  . PHE C 1 185 ? -8.675  61.687  -46.830 1.00 25.54  ? 185 PHE D CG  1 
ATOM   6169  C  CD1 . PHE C 1 185 ? -7.924  60.896  -45.981 1.00 25.38  ? 185 PHE D CD1 1 
ATOM   6170  C  CD2 . PHE C 1 185 ? -9.995  61.350  -47.039 1.00 22.10  ? 185 PHE D CD2 1 
ATOM   6171  C  CE1 . PHE C 1 185 ? -8.481  59.777  -45.372 1.00 28.70  ? 185 PHE D CE1 1 
ATOM   6172  C  CE2 . PHE C 1 185 ? -10.550 60.242  -46.441 1.00 23.18  ? 185 PHE D CE2 1 
ATOM   6173  C  CZ  . PHE C 1 185 ? -9.800  59.451  -45.610 1.00 24.05  ? 185 PHE D CZ  1 
ATOM   6174  N  N   . VAL C 1 186 ? -5.861  65.251  -47.479 1.00 27.98  ? 186 VAL D N   1 
ATOM   6175  C  CA  . VAL C 1 186 ? -5.213  66.380  -48.126 1.00 34.19  ? 186 VAL D CA  1 
ATOM   6176  C  C   . VAL C 1 186 ? -4.421  65.843  -49.300 1.00 33.77  ? 186 VAL D C   1 
ATOM   6177  O  O   . VAL C 1 186 ? -3.999  64.682  -49.294 1.00 24.91  ? 186 VAL D O   1 
ATOM   6178  C  CB  . VAL C 1 186 ? -4.285  67.150  -47.162 1.00 35.74  ? 186 VAL D CB  1 
ATOM   6179  C  CG1 . VAL C 1 186 ? -5.089  67.827  -46.078 1.00 33.67  ? 186 VAL D CG1 1 
ATOM   6180  C  CG2 . VAL C 1 186 ? -3.286  66.187  -46.545 1.00 37.32  ? 186 VAL D CG2 1 
ATOM   6181  N  N   . ASP C 1 187 ? -4.221  66.692  -50.317 1.00 28.39  ? 187 ASP D N   1 
ATOM   6182  C  CA  . ASP C 1 187 ? -3.463  66.255  -51.488 1.00 27.94  ? 187 ASP D CA  1 
ATOM   6183  C  C   . ASP C 1 187 ? -1.982  66.558  -51.279 1.00 32.16  ? 187 ASP D C   1 
ATOM   6184  O  O   . ASP C 1 187 ? -1.354  67.352  -51.963 1.00 35.20  ? 187 ASP D O   1 
ATOM   6185  C  CB  . ASP C 1 187 ? -4.020  66.847  -52.787 1.00 29.66  ? 187 ASP D CB  1 
ATOM   6186  C  CG  . ASP C 1 187 ? -4.198  68.361  -52.768 1.00 31.15  ? 187 ASP D CG  1 
ATOM   6187  O  OD1 . ASP C 1 187 ? -3.966  69.024  -51.733 1.00 34.54  ? 187 ASP D OD1 1 
ATOM   6188  O  OD2 . ASP C 1 187 ? -4.618  68.887  -53.825 1.00 26.54  ? 187 ASP D OD2 1 
ATOM   6189  N  N   . ARG C 1 188 ? -1.442  65.868  -50.283 1.00 36.08  ? 188 ARG D N   1 
ATOM   6190  C  CA  . ARG C 1 188 ? -0.033  65.873  -49.941 1.00 45.45  ? 188 ARG D CA  1 
ATOM   6191  C  C   . ARG C 1 188 ? 0.401   64.433  -49.714 1.00 51.67  ? 188 ARG D C   1 
ATOM   6192  O  O   . ARG C 1 188 ? -0.426  63.549  -49.469 1.00 48.03  ? 188 ARG D O   1 
ATOM   6193  C  CB  . ARG C 1 188 ? 0.226   66.711  -48.685 1.00 49.12  ? 188 ARG D CB  1 
ATOM   6194  C  CG  . ARG C 1 188 ? -0.362  68.103  -48.766 1.00 43.18  ? 188 ARG D CG  1 
ATOM   6195  C  CD  . ARG C 1 188 ? 0.206   69.042  -47.711 1.00 56.06  ? 188 ARG D CD  1 
ATOM   6196  N  NE  . ARG C 1 188 ? -0.371  68.829  -46.384 1.00 47.99  ? 188 ARG D NE  1 
ATOM   6197  C  CZ  . ARG C 1 188 ? -1.407  69.512  -45.901 1.00 47.72  ? 188 ARG D CZ  1 
ATOM   6198  N  NH1 . ARG C 1 188 ? -2.049  70.413  -46.633 1.00 37.11  ? 188 ARG D NH1 1 
ATOM   6199  N  NH2 . ARG C 1 188 ? -1.813  69.283  -44.653 1.00 47.57  ? 188 ARG D NH2 1 
ATOM   6200  N  N   . GLN C 1 189 ? 1.710   64.196  -49.785 1.00 61.00  ? 189 GLN D N   1 
ATOM   6201  C  CA  . GLN C 1 189 ? 2.249   62.866  -49.507 1.00 63.29  ? 189 GLN D CA  1 
ATOM   6202  C  C   . GLN C 1 189 ? 2.667   62.811  -48.040 1.00 63.33  ? 189 GLN D C   1 
ATOM   6203  O  O   . GLN C 1 189 ? 3.834   62.980  -47.678 1.00 70.37  ? 189 GLN D O   1 
ATOM   6204  C  CB  . GLN C 1 189 ? 3.402   62.523  -50.441 1.00 69.13  ? 189 GLN D CB  1 
ATOM   6205  C  CG  . GLN C 1 189 ? 3.905   61.086  -50.254 1.00 66.57  ? 189 GLN D CG  1 
ATOM   6206  C  CD  . GLN C 1 189 ? 4.809   60.626  -51.384 1.00 72.65  ? 189 GLN D CD  1 
ATOM   6207  O  OE1 . GLN C 1 189 ? 4.985   61.330  -52.385 1.00 76.77  ? 189 GLN D OE1 1 
ATOM   6208  N  NE2 . GLN C 1 189 ? 5.368   59.427  -51.242 1.00 66.90  ? 189 GLN D NE2 1 
ATOM   6209  N  N   . THR C 1 190 ? 1.671   62.616  -47.179 1.00 58.88  ? 190 THR D N   1 
ATOM   6210  C  CA  . THR C 1 190 ? 1.878   62.469  -45.746 1.00 61.22  ? 190 THR D CA  1 
ATOM   6211  C  C   . THR C 1 190 ? 1.114   61.238  -45.277 1.00 55.67  ? 190 THR D C   1 
ATOM   6212  O  O   . THR C 1 190 ? 0.286   60.680  -46.002 1.00 55.06  ? 190 THR D O   1 
ATOM   6213  C  CB  . THR C 1 190 ? 1.423   63.710  -44.957 1.00 57.01  ? 190 THR D CB  1 
ATOM   6214  O  OG1 . THR C 1 190 ? -0.001  63.855  -45.055 1.00 55.99  ? 190 THR D OG1 1 
ATOM   6215  C  CG2 . THR C 1 190 ? 2.104   64.967  -45.485 1.00 60.10  ? 190 THR D CG2 1 
ATOM   6216  N  N   . ALA C 1 191 ? 1.421   60.802  -44.057 1.00 54.90  ? 191 ALA D N   1 
ATOM   6217  C  CA  . ALA C 1 191 ? 0.772   59.629  -43.485 1.00 51.87  ? 191 ALA D CA  1 
ATOM   6218  C  C   . ALA C 1 191 ? -0.674  59.978  -43.172 1.00 54.03  ? 191 ALA D C   1 
ATOM   6219  O  O   . ALA C 1 191 ? -0.947  60.817  -42.305 1.00 56.69  ? 191 ALA D O   1 
ATOM   6220  C  CB  . ALA C 1 191 ? 1.508   59.159  -42.233 1.00 52.96  ? 191 ALA D CB  1 
ATOM   6221  N  N   . GLN C 1 192 ? -1.598  59.355  -43.895 1.00 49.76  ? 192 GLN D N   1 
ATOM   6222  C  CA  . GLN C 1 192 ? -3.024  59.567  -43.700 1.00 46.74  ? 192 GLN D CA  1 
ATOM   6223  C  C   . GLN C 1 192 ? -3.687  58.209  -43.587 1.00 35.44  ? 192 GLN D C   1 
ATOM   6224  O  O   . GLN C 1 192 ? -3.364  57.296  -44.349 1.00 44.89  ? 192 GLN D O   1 
ATOM   6225  C  CB  . GLN C 1 192 ? -3.641  60.357  -44.871 1.00 39.04  ? 192 GLN D CB  1 
ATOM   6226  C  CG  . GLN C 1 192 ? -2.861  61.580  -45.276 1.00 36.49  ? 192 GLN D CG  1 
ATOM   6227  C  CD  . GLN C 1 192 ? -3.537  62.367  -46.372 1.00 36.86  ? 192 GLN D CD  1 
ATOM   6228  O  OE1 . GLN C 1 192 ? -4.694  62.762  -46.243 1.00 32.13  ? 192 GLN D OE1 1 
ATOM   6229  N  NE2 . GLN C 1 192 ? -2.805  62.623  -47.457 1.00 36.57  ? 192 GLN D NE2 1 
ATOM   6230  N  N   . ALA C 1 193 ? -4.586  58.072  -42.623 1.00 32.69  ? 193 ALA D N   1 
ATOM   6231  C  CA  . ALA C 1 193 ? -5.315  56.835  -42.386 1.00 30.90  ? 193 ALA D CA  1 
ATOM   6232  C  C   . ALA C 1 193 ? -6.808  57.102  -42.525 1.00 34.62  ? 193 ALA D C   1 
ATOM   6233  O  O   . ALA C 1 193 ? -7.302  58.148  -42.086 1.00 33.59  ? 193 ALA D O   1 
ATOM   6234  C  CB  . ALA C 1 193 ? -4.982  56.260  -41.009 1.00 29.83  ? 193 ALA D CB  1 
ATOM   6235  N  N   . ALA C 1 194 ? -7.525  56.147  -43.123 1.00 33.76  ? 194 ALA D N   1 
ATOM   6236  C  CA  . ALA C 1 194 ? -8.948  56.328  -43.417 1.00 32.01  ? 194 ALA D CA  1 
ATOM   6237  C  C   . ALA C 1 194 ? -9.772  56.741  -42.188 1.00 43.13  ? 194 ALA D C   1 
ATOM   6238  O  O   . ALA C 1 194 ? -10.438 57.789  -42.197 1.00 41.59  ? 194 ALA D O   1 
ATOM   6239  C  CB  . ALA C 1 194 ? -9.509  55.045  -44.034 1.00 36.11  ? 194 ALA D CB  1 
ATOM   6240  N  N   . GLY C 1 195 ? -9.740  55.949  -41.121 1.00 33.23  ? 195 GLY D N   1 
ATOM   6241  C  CA  . GLY C 1 195 ? -10.701 56.108  -40.045 1.00 29.70  ? 195 GLY D CA  1 
ATOM   6242  C  C   . GLY C 1 195 ? -11.652 54.920  -39.934 1.00 34.70  ? 195 GLY D C   1 
ATOM   6243  O  O   . GLY C 1 195 ? -11.721 54.039  -40.792 1.00 34.91  ? 195 GLY D O   1 
ATOM   6244  N  N   . THR C 1 196 ? -12.410 54.912  -38.848 1.00 40.62  ? 196 THR D N   1 
ATOM   6245  C  CA  . THR C 1 196 ? -13.239 53.755  -38.559 1.00 41.80  ? 196 THR D CA  1 
ATOM   6246  C  C   . THR C 1 196 ? -14.505 53.781  -39.406 1.00 38.79  ? 196 THR D C   1 
ATOM   6247  O  O   . THR C 1 196 ? -15.045 54.848  -39.719 1.00 34.88  ? 196 THR D O   1 
ATOM   6248  C  CB  . THR C 1 196 ? -13.587 53.711  -37.073 1.00 41.33  ? 196 THR D CB  1 
ATOM   6249  O  OG1 . THR C 1 196 ? -14.207 52.455  -36.772 1.00 56.81  ? 196 THR D OG1 1 
ATOM   6250  C  CG2 . THR C 1 196 ? -14.528 54.844  -36.706 1.00 41.70  ? 196 THR D CG2 1 
ATOM   6251  N  N   . ASP C 1 197 ? -14.901 52.596  -39.854 1.00 36.16  ? 197 ASP D N   1 
ATOM   6252  C  CA  . ASP C 1 197 ? -16.052 52.527  -40.788 1.00 42.53  ? 197 ASP D CA  1 
ATOM   6253  C  C   . ASP C 1 197 ? -17.195 51.697  -40.213 1.00 36.06  ? 197 ASP D C   1 
ATOM   6254  O  O   . ASP C 1 197 ? -16.969 50.913  -39.294 1.00 32.20  ? 197 ASP D O   1 
ATOM   6255  C  CB  . ASP C 1 197 ? -15.641 51.990  -42.162 1.00 40.63  ? 197 ASP D CB  1 
ATOM   6256  C  CG  . ASP C 1 197 ? -16.592 52.373  -43.282 1.00 36.36  ? 197 ASP D CG  1 
ATOM   6257  O  OD1 . ASP C 1 197 ? -17.243 53.421  -43.161 1.00 33.96  ? 197 ASP D OD1 1 
ATOM   6258  O  OD2 . ASP C 1 197 ? -16.670 51.615  -44.264 1.00 39.63  ? 197 ASP D OD2 1 
ATOM   6259  N  N   . THR C 1 198 ? -18.376 51.890  -40.779 1.00 35.16  ? 198 THR D N   1 
ATOM   6260  C  CA  . THR C 1 198 ? -19.577 51.201  -40.288 1.00 31.93  ? 198 THR D CA  1 
ATOM   6261  C  C   . THR C 1 198 ? -20.306 50.553  -41.456 1.00 29.43  ? 198 THR D C   1 
ATOM   6262  O  O   . THR C 1 198 ? -20.177 51.046  -42.571 1.00 24.16  ? 198 THR D O   1 
ATOM   6263  C  CB  . THR C 1 198 ? -20.482 52.202  -39.552 1.00 28.52  ? 198 THR D CB  1 
ATOM   6264  O  OG1 . THR C 1 198 ? -20.598 53.385  -40.339 1.00 36.08  ? 198 THR D OG1 1 
ATOM   6265  C  CG2 . THR C 1 198 ? -19.968 52.558  -38.176 1.00 34.86  ? 198 THR D CG2 1 
ATOM   6266  N  N   . THR C 1 199 ? -21.027 49.473  -41.185 1.00 27.78  ? 199 THR D N   1 
ATOM   6267  C  CA  . THR C 1 199 ? -21.878 48.883  -42.208 1.00 22.36  ? 199 THR D CA  1 
ATOM   6268  C  C   . THR C 1 199 ? -23.120 49.738  -42.407 1.00 26.54  ? 199 THR D C   1 
ATOM   6269  O  O   . THR C 1 199 ? -23.726 50.210  -41.439 1.00 28.33  ? 199 THR D O   1 
ATOM   6270  C  CB  . THR C 1 199 ? -22.295 47.477  -41.799 1.00 21.89  ? 199 THR D CB  1 
ATOM   6271  O  OG1 . THR C 1 199 ? -21.128 46.687  -41.606 1.00 32.16  ? 199 THR D OG1 1 
ATOM   6272  C  CG2 . THR C 1 199 ? -23.137 46.837  -42.888 1.00 26.82  ? 199 THR D CG2 1 
ATOM   6273  N  N   . ILE C 1 200 ? -23.468 49.985  -43.672 1.00 27.17  ? 200 ILE D N   1 
ATOM   6274  C  CA  . ILE C 1 200 ? -24.631 50.866  -43.992 1.00 25.63  ? 200 ILE D CA  1 
ATOM   6275  C  C   . ILE C 1 200 ? -25.905 50.060  -43.773 1.00 25.11  ? 200 ILE D C   1 
ATOM   6276  O  O   . ILE C 1 200 ? -26.302 49.325  -44.673 1.00 27.52  ? 200 ILE D O   1 
ATOM   6277  C  CB  . ILE C 1 200 ? -24.495 51.501  -45.388 1.00 20.45  ? 200 ILE D CB  1 
ATOM   6278  C  CG1 . ILE C 1 200 ? -23.090 52.076  -45.581 1.00 20.39  ? 200 ILE D CG1 1 
ATOM   6279  C  CG2 . ILE C 1 200 ? -25.574 52.543  -45.617 1.00 16.87  ? 200 ILE D CG2 1 
ATOM   6280  C  CD1 . ILE C 1 200 ? -22.664 52.224  -47.017 1.00 23.19  ? 200 ILE D CD1 1 
ATOM   6281  N  N   . THR C 1 201 ? -26.512 50.240  -42.608 1.00 25.90  ? 201 THR D N   1 
ATOM   6282  C  CA  . THR C 1 201 ? -27.656 49.421  -42.211 1.00 20.82  ? 201 THR D CA  1 
ATOM   6283  C  C   . THR C 1 201 ? -28.822 49.582  -43.172 1.00 19.10  ? 201 THR D C   1 
ATOM   6284  O  O   . THR C 1 201 ? -29.436 48.589  -43.582 1.00 20.07  ? 201 THR D O   1 
ATOM   6285  C  CB  . THR C 1 201 ? -28.066 49.778  -40.776 1.00 23.33  ? 201 THR D CB  1 
ATOM   6286  O  OG1 . THR C 1 201 ? -26.891 49.842  -39.962 1.00 22.78  ? 201 THR D OG1 1 
ATOM   6287  C  CG2 . THR C 1 201 ? -29.029 48.748  -40.173 1.00 24.88  ? 201 THR D CG2 1 
ATOM   6288  N  N   . VAL C 1 202 ? -29.151 50.827  -43.548 1.00 19.45  ? 202 VAL D N   1 
ATOM   6289  C  CA  . VAL C 1 202 ? -30.289 51.033  -44.444 1.00 18.35  ? 202 VAL D CA  1 
ATOM   6290  C  C   . VAL C 1 202 ? -30.042 50.361  -45.789 1.00 21.02  ? 202 VAL D C   1 
ATOM   6291  O  O   . VAL C 1 202 ? -30.973 49.827  -46.409 1.00 20.39  ? 202 VAL D O   1 
ATOM   6292  C  CB  . VAL C 1 202 ? -30.612 52.524  -44.584 1.00 22.24  ? 202 VAL D CB  1 
ATOM   6293  C  CG1 . VAL C 1 202 ? -29.450 53.259  -45.213 1.00 25.64  ? 202 VAL D CG1 1 
ATOM   6294  C  CG2 . VAL C 1 202 ? -31.892 52.713  -45.403 1.00 21.01  ? 202 VAL D CG2 1 
ATOM   6295  N  N   . ASN C 1 203 ? -28.782 50.310  -46.229 1.00 19.50  ? 203 ASN D N   1 
ATOM   6296  C  CA  . ASN C 1 203 ? -28.464 49.603  -47.466 1.00 19.65  ? 203 ASN D CA  1 
ATOM   6297  C  C   . ASN C 1 203 ? -28.565 48.077  -47.290 1.00 20.37  ? 203 ASN D C   1 
ATOM   6298  O  O   . ASN C 1 203 ? -28.977 47.370  -48.212 1.00 19.05  ? 203 ASN D O   1 
ATOM   6299  C  CB  . ASN C 1 203 ? -27.071 50.011  -47.933 1.00 16.00  ? 203 ASN D CB  1 
ATOM   6300  C  CG  . ASN C 1 203 ? -27.017 51.435  -48.469 1.00 23.27  ? 203 ASN D CG  1 
ATOM   6301  O  OD1 . ASN C 1 203 ? -28.041 52.136  -48.576 1.00 18.75  ? 203 ASN D OD1 1 
ATOM   6302  N  ND2 . ASN C 1 203 ? -25.802 51.887  -48.783 1.00 21.50  ? 203 ASN D ND2 1 
ATOM   6303  N  N   . VAL C 1 204 ? -28.169 47.539  -46.134 1.00 20.29  ? 204 VAL D N   1 
ATOM   6304  C  CA  . VAL C 1 204 ? -28.329 46.097  -45.919 1.00 24.05  ? 204 VAL D CA  1 
ATOM   6305  C  C   . VAL C 1 204 ? -29.799 45.699  -45.998 1.00 19.68  ? 204 VAL D C   1 
ATOM   6306  O  O   . VAL C 1 204 ? -30.162 44.726  -46.669 1.00 18.61  ? 204 VAL D O   1 
ATOM   6307  C  CB  . VAL C 1 204 ? -27.714 45.670  -44.579 1.00 18.83  ? 204 VAL D CB  1 
ATOM   6308  C  CG1 . VAL C 1 204 ? -28.046 44.195  -44.309 1.00 21.49  ? 204 VAL D CG1 1 
ATOM   6309  C  CG2 . VAL C 1 204 ? -26.226 45.888  -44.599 1.00 19.17  ? 204 VAL D CG2 1 
ATOM   6310  N  N   . LEU C 1 205 ? -30.665 46.463  -45.324 1.00 18.60  ? 205 LEU D N   1 
ATOM   6311  C  CA  . LEU C 1 205 ? -32.098 46.182  -45.334 1.00 20.32  ? 205 LEU D CA  1 
ATOM   6312  C  C   . LEU C 1 205 ? -32.666 46.247  -46.745 1.00 24.07  ? 205 LEU D C   1 
ATOM   6313  O  O   . LEU C 1 205 ? -33.410 45.346  -47.166 1.00 18.50  ? 205 LEU D O   1 
ATOM   6314  C  CB  . LEU C 1 205 ? -32.816 47.174  -44.421 1.00 22.98  ? 205 LEU D CB  1 
ATOM   6315  C  CG  . LEU C 1 205 ? -32.433 46.922  -42.948 1.00 25.23  ? 205 LEU D CG  1 
ATOM   6316  C  CD1 . LEU C 1 205 ? -32.757 48.159  -42.078 1.00 27.64  ? 205 LEU D CD1 1 
ATOM   6317  C  CD2 . LEU C 1 205 ? -33.099 45.656  -42.412 1.00 18.21  ? 205 LEU D CD2 1 
ATOM   6318  N  N   . ALA C 1 206 ? -32.289 47.293  -47.504 1.00 17.23  ? 206 ALA D N   1 
ATOM   6319  C  CA  . ALA C 1 206 ? -32.733 47.420  -48.884 1.00 15.61  ? 206 ALA D CA  1 
ATOM   6320  C  C   . ALA C 1 206 ? -32.372 46.183  -49.704 1.00 19.63  ? 206 ALA D C   1 
ATOM   6321  O  O   . ALA C 1 206 ? -33.158 45.715  -50.538 1.00 18.08  ? 206 ALA D O   1 
ATOM   6322  C  CB  . ALA C 1 206 ? -32.105 48.674  -49.499 1.00 19.19  ? 206 ALA D CB  1 
ATOM   6323  N  N   . TRP C 1 207 ? -31.178 45.655  -49.489 1.00 20.13  ? 207 TRP D N   1 
ATOM   6324  C  CA  . TRP C 1 207 ? -30.721 44.505  -50.238 1.00 21.02  ? 207 TRP D CA  1 
ATOM   6325  C  C   . TRP C 1 207 ? -31.447 43.241  -49.799 1.00 23.33  ? 207 TRP D C   1 
ATOM   6326  O  O   . TRP C 1 207 ? -31.655 42.339  -50.616 1.00 21.89  ? 207 TRP D O   1 
ATOM   6327  C  CB  . TRP C 1 207 ? -29.209 44.400  -50.069 1.00 22.07  ? 207 TRP D CB  1 
ATOM   6328  C  CG  . TRP C 1 207 ? -28.554 43.140  -50.518 1.00 23.69  ? 207 TRP D CG  1 
ATOM   6329  C  CD1 . TRP C 1 207 ? -28.183 42.799  -51.789 1.00 23.96  ? 207 TRP D CD1 1 
ATOM   6330  C  CD2 . TRP C 1 207 ? -28.145 42.063  -49.673 1.00 24.89  ? 207 TRP D CD2 1 
ATOM   6331  N  NE1 . TRP C 1 207 ? -27.568 41.562  -51.786 1.00 25.41  ? 207 TRP D NE1 1 
ATOM   6332  C  CE2 . TRP C 1 207 ? -27.537 41.087  -50.501 1.00 24.73  ? 207 TRP D CE2 1 
ATOM   6333  C  CE3 . TRP C 1 207 ? -28.234 41.826  -48.293 1.00 25.19  ? 207 TRP D CE3 1 
ATOM   6334  C  CZ2 . TRP C 1 207 ? -27.041 39.887  -49.999 1.00 24.61  ? 207 TRP D CZ2 1 
ATOM   6335  C  CZ3 . TRP C 1 207 ? -27.723 40.633  -47.789 1.00 26.74  ? 207 TRP D CZ3 1 
ATOM   6336  C  CH2 . TRP C 1 207 ? -27.134 39.679  -48.644 1.00 27.02  ? 207 TRP D CH2 1 
ATOM   6337  N  N   . LEU C 1 208 ? -31.814 43.131  -48.518 1.00 19.01  ? 208 LEU D N   1 
ATOM   6338  C  CA  . LEU C 1 208 ? -32.692 42.024  -48.135 1.00 22.16  ? 208 LEU D CA  1 
ATOM   6339  C  C   . LEU C 1 208 ? -34.029 42.115  -48.856 1.00 21.97  ? 208 LEU D C   1 
ATOM   6340  O  O   . LEU C 1 208 ? -34.608 41.086  -49.242 1.00 21.59  ? 208 LEU D O   1 
ATOM   6341  C  CB  . LEU C 1 208 ? -32.892 41.969  -46.624 1.00 16.61  ? 208 LEU D CB  1 
ATOM   6342  C  CG  . LEU C 1 208 ? -31.621 41.531  -45.903 1.00 19.78  ? 208 LEU D CG  1 
ATOM   6343  C  CD1 . LEU C 1 208 ? -31.785 41.657  -44.379 1.00 19.57  ? 208 LEU D CD1 1 
ATOM   6344  C  CD2 . LEU C 1 208 ? -31.177 40.130  -46.310 1.00 17.17  ? 208 LEU D CD2 1 
ATOM   6345  N  N   . TYR C 1 209 ? -34.536 43.339  -49.053 1.00 18.88  ? 209 TYR D N   1 
ATOM   6346  C  CA  . TYR C 1 209 ? -35.783 43.498  -49.792 1.00 19.56  ? 209 TYR D CA  1 
ATOM   6347  C  C   . TYR C 1 209 ? -35.634 43.063  -51.238 1.00 22.66  ? 209 TYR D C   1 
ATOM   6348  O  O   . TYR C 1 209 ? -36.542 42.428  -51.793 1.00 22.47  ? 209 TYR D O   1 
ATOM   6349  C  CB  . TYR C 1 209 ? -36.284 44.934  -49.717 1.00 20.83  ? 209 TYR D CB  1 
ATOM   6350  C  CG  . TYR C 1 209 ? -37.059 45.224  -48.446 1.00 23.24  ? 209 TYR D CG  1 
ATOM   6351  C  CD1 . TYR C 1 209 ? -38.295 44.631  -48.210 1.00 25.98  ? 209 TYR D CD1 1 
ATOM   6352  C  CD2 . TYR C 1 209 ? -36.560 46.103  -47.490 1.00 22.39  ? 209 TYR D CD2 1 
ATOM   6353  C  CE1 . TYR C 1 209 ? -39.008 44.899  -47.045 1.00 25.94  ? 209 TYR D CE1 1 
ATOM   6354  C  CE2 . TYR C 1 209 ? -37.261 46.376  -46.329 1.00 23.35  ? 209 TYR D CE2 1 
ATOM   6355  C  CZ  . TYR C 1 209 ? -38.481 45.773  -46.114 1.00 23.25  ? 209 TYR D CZ  1 
ATOM   6356  O  OH  . TYR C 1 209 ? -39.170 46.042  -44.964 1.00 23.85  ? 209 TYR D OH  1 
ATOM   6357  N  N   . ALA C 1 210 ? -34.520 43.432  -51.884 1.00 19.32  ? 210 ALA D N   1 
ATOM   6358  C  CA  . ALA C 1 210 ? -34.254 42.924  -53.225 1.00 21.15  ? 210 ALA D CA  1 
ATOM   6359  C  C   . ALA C 1 210 ? -34.303 41.398  -53.244 1.00 23.29  ? 210 ALA D C   1 
ATOM   6360  O  O   . ALA C 1 210 ? -34.888 40.803  -54.153 1.00 25.02  ? 210 ALA D O   1 
ATOM   6361  C  CB  . ALA C 1 210 ? -32.893 43.420  -53.730 1.00 18.11  ? 210 ALA D CB  1 
ATOM   6362  N  N   . ALA C 1 211 ? -33.738 40.754  -52.219 1.00 22.01  ? 211 ALA D N   1 
ATOM   6363  C  CA  . ALA C 1 211 ? -33.727 39.296  -52.163 1.00 26.72  ? 211 ALA D CA  1 
ATOM   6364  C  C   . ALA C 1 211 ? -35.144 38.750  -52.139 1.00 24.86  ? 211 ALA D C   1 
ATOM   6365  O  O   . ALA C 1 211 ? -35.473 37.813  -52.873 1.00 27.43  ? 211 ALA D O   1 
ATOM   6366  C  CB  . ALA C 1 211 ? -32.944 38.813  -50.938 1.00 23.01  ? 211 ALA D CB  1 
ATOM   6367  N  N   . VAL C 1 212 ? -36.001 39.344  -51.315 1.00 19.08  ? 212 VAL D N   1 
ATOM   6368  C  CA  . VAL C 1 212 ? -37.396 38.923  -51.255 1.00 21.77  ? 212 VAL D CA  1 
ATOM   6369  C  C   . VAL C 1 212 ? -38.075 39.101  -52.611 1.00 24.61  ? 212 VAL D C   1 
ATOM   6370  O  O   . VAL C 1 212 ? -38.746 38.190  -53.111 1.00 23.50  ? 212 VAL D O   1 
ATOM   6371  C  CB  . VAL C 1 212 ? -38.136 39.719  -50.169 1.00 17.74  ? 212 VAL D CB  1 
ATOM   6372  C  CG1 . VAL C 1 212 ? -39.625 39.385  -50.201 1.00 21.66  ? 212 VAL D CG1 1 
ATOM   6373  C  CG2 . VAL C 1 212 ? -37.492 39.470  -48.807 1.00 25.33  ? 212 VAL D CG2 1 
ATOM   6374  N  N   . ILE C 1 213 ? -37.912 40.286  -53.221 1.00 23.04  ? 213 ILE D N   1 
ATOM   6375  C  CA  . ILE C 1 213 ? -38.473 40.567  -54.538 1.00 19.35  ? 213 ILE D CA  1 
ATOM   6376  C  C   . ILE C 1 213 ? -38.029 39.527  -55.558 1.00 21.57  ? 213 ILE D C   1 
ATOM   6377  O  O   . ILE C 1 213 ? -38.814 39.106  -56.419 1.00 26.07  ? 213 ILE D O   1 
ATOM   6378  C  CB  . ILE C 1 213 ? -38.086 41.996  -54.969 1.00 24.32  ? 213 ILE D CB  1 
ATOM   6379  C  CG1 . ILE C 1 213 ? -38.845 43.037  -54.117 1.00 25.05  ? 213 ILE D CG1 1 
ATOM   6380  C  CG2 . ILE C 1 213 ? -38.313 42.213  -56.465 1.00 20.17  ? 213 ILE D CG2 1 
ATOM   6381  C  CD1 . ILE C 1 213 ? -38.233 44.433  -54.167 1.00 22.68  ? 213 ILE D CD1 1 
ATOM   6382  N  N   . ASN C 1 214 ? -36.800 39.034  -55.437 1.00 21.64  ? 214 ASN D N   1 
ATOM   6383  C  CA  . ASN C 1 214 ? -36.282 38.077  -56.412 1.00 27.62  ? 214 ASN D CA  1 
ATOM   6384  C  C   . ASN C 1 214 ? -36.459 36.623  -55.986 1.00 27.02  ? 214 ASN D C   1 
ATOM   6385  O  O   . ASN C 1 214 ? -35.917 35.742  -56.651 1.00 35.76  ? 214 ASN D O   1 
ATOM   6386  C  CB  . ASN C 1 214 ? -34.798 38.332  -56.685 1.00 24.20  ? 214 ASN D CB  1 
ATOM   6387  C  CG  . ASN C 1 214 ? -34.567 39.536  -57.590 1.00 33.78  ? 214 ASN D CG  1 
ATOM   6388  O  OD1 . ASN C 1 214 ? -34.581 39.417  -58.817 1.00 36.30  ? 214 ASN D OD1 1 
ATOM   6389  N  ND2 . ASN C 1 214 ? -34.366 40.703  -56.985 1.00 28.80  ? 214 ASN D ND2 1 
ATOM   6390  N  N   . GLY C 1 215 ? -37.255 36.346  -54.955 1.00 24.88  ? 215 GLY D N   1 
ATOM   6391  C  CA  . GLY C 1 215 ? -37.569 34.977  -54.572 1.00 28.67  ? 215 GLY D CA  1 
ATOM   6392  C  C   . GLY C 1 215 ? -36.700 34.349  -53.497 1.00 30.15  ? 215 GLY D C   1 
ATOM   6393  O  O   . GLY C 1 215 ? -36.996 33.219  -53.074 1.00 37.64  ? 215 GLY D O   1 
ATOM   6394  N  N   . ASP C 1 216 ? -35.666 35.047  -53.013 1.00 31.09  ? 216 ASP D N   1 
ATOM   6395  C  CA  . ASP C 1 216 ? -34.826 34.569  -51.911 1.00 35.46  ? 216 ASP D CA  1 
ATOM   6396  C  C   . ASP C 1 216 ? -35.480 34.909  -50.566 1.00 41.16  ? 216 ASP D C   1 
ATOM   6397  O  O   . ASP C 1 216 ? -35.429 36.066  -50.123 1.00 38.59  ? 216 ASP D O   1 
ATOM   6398  C  CB  . ASP C 1 216 ? -33.444 35.208  -52.004 1.00 34.46  ? 216 ASP D CB  1 
ATOM   6399  C  CG  . ASP C 1 216 ? -32.491 34.416  -52.860 1.00 42.55  ? 216 ASP D CG  1 
ATOM   6400  O  OD1 . ASP C 1 216 ? -32.895 33.321  -53.297 1.00 50.39  ? 216 ASP D OD1 1 
ATOM   6401  O  OD2 . ASP C 1 216 ? -31.324 34.859  -53.079 1.00 38.70  ? 216 ASP D OD2 1 
ATOM   6402  N  N   . ARG C 1 217 ? -35.990 33.882  -49.857 1.00 35.04  ? 217 ARG D N   1 
ATOM   6403  C  CA  . ARG C 1 217 ? -36.881 34.077  -48.708 1.00 33.12  ? 217 ARG D CA  1 
ATOM   6404  C  C   . ARG C 1 217 ? -36.475 33.320  -47.443 1.00 35.10  ? 217 ARG D C   1 
ATOM   6405  O  O   . ARG C 1 217 ? -37.125 33.505  -46.405 1.00 36.54  ? 217 ARG D O   1 
ATOM   6406  C  CB  . ARG C 1 217 ? -38.317 33.607  -49.047 1.00 46.93  ? 217 ARG D CB  1 
ATOM   6407  C  CG  . ARG C 1 217 ? -39.080 34.250  -50.220 1.00 47.63  ? 217 ARG D CG  1 
ATOM   6408  C  CD  . ARG C 1 217 ? -40.463 33.552  -50.432 1.00 54.95  ? 217 ARG D CD  1 
ATOM   6409  N  NE  . ARG C 1 217 ? -40.972 33.044  -49.164 1.00 59.93  ? 217 ARG D NE  1 
ATOM   6410  C  CZ  . ARG C 1 217 ? -41.797 33.707  -48.364 1.00 61.94  ? 217 ARG D CZ  1 
ATOM   6411  N  NH1 . ARG C 1 217 ? -42.167 34.959  -48.638 1.00 48.69  ? 217 ARG D NH1 1 
ATOM   6412  N  NH2 . ARG C 1 217 ? -42.193 33.128  -47.227 1.00 54.99  ? 217 ARG D NH2 1 
ATOM   6413  N  N   . TRP C 1 218 ? -35.438 32.469  -47.490 1.00 33.76  ? 218 TRP D N   1 
ATOM   6414  C  CA  . TRP C 1 218 ? -35.166 31.558  -46.375 1.00 30.19  ? 218 TRP D CA  1 
ATOM   6415  C  C   . TRP C 1 218 ? -34.867 32.280  -45.064 1.00 30.23  ? 218 TRP D C   1 
ATOM   6416  O  O   . TRP C 1 218 ? -35.011 31.683  -43.992 1.00 27.83  ? 218 TRP D O   1 
ATOM   6417  C  CB  . TRP C 1 218 ? -33.992 30.613  -46.711 1.00 30.51  ? 218 TRP D CB  1 
ATOM   6418  C  CG  . TRP C 1 218 ? -32.658 31.315  -46.969 1.00 27.33  ? 218 TRP D CG  1 
ATOM   6419  C  CD1 . TRP C 1 218 ? -32.156 31.694  -48.175 1.00 29.86  ? 218 TRP D CD1 1 
ATOM   6420  C  CD2 . TRP C 1 218 ? -31.664 31.681  -45.992 1.00 24.73  ? 218 TRP D CD2 1 
ATOM   6421  N  NE1 . TRP C 1 218 ? -30.931 32.294  -48.011 1.00 29.06  ? 218 TRP D NE1 1 
ATOM   6422  C  CE2 . TRP C 1 218 ? -30.607 32.293  -46.682 1.00 26.18  ? 218 TRP D CE2 1 
ATOM   6423  C  CE3 . TRP C 1 218 ? -31.575 31.559  -44.596 1.00 32.78  ? 218 TRP D CE3 1 
ATOM   6424  C  CZ2 . TRP C 1 218 ? -29.478 32.795  -46.033 1.00 29.10  ? 218 TRP D CZ2 1 
ATOM   6425  C  CZ3 . TRP C 1 218 ? -30.446 32.047  -43.954 1.00 31.87  ? 218 TRP D CZ3 1 
ATOM   6426  C  CH2 . TRP C 1 218 ? -29.417 32.670  -44.674 1.00 31.54  ? 218 TRP D CH2 1 
ATOM   6427  N  N   . PHE C 1 219 ? -34.411 33.527  -45.123 1.00 27.49  ? 219 PHE D N   1 
ATOM   6428  C  CA  . PHE C 1 219 ? -33.984 34.258  -43.943 1.00 24.29  ? 219 PHE D CA  1 
ATOM   6429  C  C   . PHE C 1 219 ? -35.132 35.000  -43.257 1.00 27.10  ? 219 PHE D C   1 
ATOM   6430  O  O   . PHE C 1 219 ? -34.932 35.572  -42.184 1.00 29.75  ? 219 PHE D O   1 
ATOM   6431  C  CB  . PHE C 1 219 ? -32.880 35.236  -44.347 1.00 25.92  ? 219 PHE D CB  1 
ATOM   6432  C  CG  . PHE C 1 219 ? -33.282 36.119  -45.491 1.00 25.47  ? 219 PHE D CG  1 
ATOM   6433  C  CD1 . PHE C 1 219 ? -33.980 37.292  -45.259 1.00 25.34  ? 219 PHE D CD1 1 
ATOM   6434  C  CD2 . PHE C 1 219 ? -33.029 35.737  -46.801 1.00 30.32  ? 219 PHE D CD2 1 
ATOM   6435  C  CE1 . PHE C 1 219 ? -34.382 38.106  -46.315 1.00 26.23  ? 219 PHE D CE1 1 
ATOM   6436  C  CE2 . PHE C 1 219 ? -33.429 36.537  -47.864 1.00 32.29  ? 219 PHE D CE2 1 
ATOM   6437  C  CZ  . PHE C 1 219 ? -34.112 37.727  -47.617 1.00 28.98  ? 219 PHE D CZ  1 
ATOM   6438  N  N   . LEU C 1 220 ? -36.319 35.033  -43.847 1.00 27.00  ? 220 LEU D N   1 
ATOM   6439  C  CA  . LEU C 1 220 ? -37.444 35.687  -43.192 1.00 27.64  ? 220 LEU D CA  1 
ATOM   6440  C  C   . LEU C 1 220 ? -37.942 34.830  -42.034 1.00 32.23  ? 220 LEU D C   1 
ATOM   6441  O  O   . LEU C 1 220 ? -37.992 33.601  -42.122 1.00 32.83  ? 220 LEU D O   1 
ATOM   6442  C  CB  . LEU C 1 220 ? -38.588 35.919  -44.183 1.00 24.63  ? 220 LEU D CB  1 
ATOM   6443  C  CG  . LEU C 1 220 ? -38.296 36.791  -45.403 1.00 30.13  ? 220 LEU D CG  1 
ATOM   6444  C  CD1 . LEU C 1 220 ? -39.447 36.734  -46.406 1.00 29.36  ? 220 LEU D CD1 1 
ATOM   6445  C  CD2 . LEU C 1 220 ? -37.987 38.230  -44.981 1.00 21.28  ? 220 LEU D CD2 1 
ATOM   6446  N  N   . ASN C 1 221 ? -38.289 35.477  -40.932 1.00 29.94  ? 221 ASN D N   1 
ATOM   6447  C  CA  . ASN C 1 221 ? -38.813 34.766  -39.785 1.00 30.02  ? 221 ASN D CA  1 
ATOM   6448  C  C   . ASN C 1 221 ? -40.156 35.387  -39.418 1.00 27.68  ? 221 ASN D C   1 
ATOM   6449  O  O   . ASN C 1 221 ? -40.666 36.274  -40.107 1.00 32.07  ? 221 ASN D O   1 
ATOM   6450  C  CB  . ASN C 1 221 ? -37.818 34.768  -38.611 1.00 26.84  ? 221 ASN D CB  1 
ATOM   6451  C  CG  . ASN C 1 221 ? -37.475 36.161  -38.102 1.00 31.79  ? 221 ASN D CG  1 
ATOM   6452  O  OD1 . ASN C 1 221 ? -38.277 37.092  -38.175 1.00 31.58  ? 221 ASN D OD1 1 
ATOM   6453  N  ND2 . ASN C 1 221 ? -36.292 36.290  -37.523 1.00 30.47  ? 221 ASN D ND2 1 
ATOM   6454  N  N   . ARG C 1 222 ? -40.769 34.881  -38.360 1.00 30.18  ? 222 ARG D N   1 
ATOM   6455  C  CA  . ARG C 1 222 ? -42.074 35.369  -37.941 1.00 36.34  ? 222 ARG D CA  1 
ATOM   6456  C  C   . ARG C 1 222 ? -42.001 36.383  -36.793 1.00 33.31  ? 222 ARG D C   1 
ATOM   6457  O  O   . ARG C 1 222 ? -43.010 36.633  -36.128 1.00 35.73  ? 222 ARG D O   1 
ATOM   6458  C  CB  . ARG C 1 222 ? -42.988 34.195  -37.603 1.00 34.40  ? 222 ARG D CB  1 
ATOM   6459  C  CG  . ARG C 1 222 ? -42.483 33.336  -36.503 1.00 38.54  ? 222 ARG D CG  1 
ATOM   6460  C  CD  . ARG C 1 222 ? -43.520 32.271  -36.230 1.00 52.46  ? 222 ARG D CD  1 
ATOM   6461  N  NE  . ARG C 1 222 ? -43.870 31.502  -37.418 1.00 54.56  ? 222 ARG D NE  1 
ATOM   6462  C  CZ  . ARG C 1 222 ? -44.872 30.636  -37.465 1.00 53.71  ? 222 ARG D CZ  1 
ATOM   6463  N  NH1 . ARG C 1 222 ? -45.633 30.405  -36.407 1.00 51.57  ? 222 ARG D NH1 1 
ATOM   6464  N  NH2 . ARG C 1 222 ? -45.107 29.974  -38.596 1.00 57.60  ? 222 ARG D NH2 1 
ATOM   6465  N  N   . PHE C 1 223 ? -40.831 36.941  -36.529 1.00 29.29  ? 223 PHE D N   1 
ATOM   6466  C  CA  . PHE C 1 223 ? -40.636 37.840  -35.400 1.00 29.86  ? 223 PHE D CA  1 
ATOM   6467  C  C   . PHE C 1 223 ? -40.707 39.292  -35.853 1.00 27.01  ? 223 PHE D C   1 
ATOM   6468  O  O   . PHE C 1 223 ? -40.668 39.610  -37.044 1.00 28.72  ? 223 PHE D O   1 
ATOM   6469  C  CB  . PHE C 1 223 ? -39.279 37.616  -34.734 1.00 33.68  ? 223 PHE D CB  1 
ATOM   6470  C  CG  . PHE C 1 223 ? -39.044 36.228  -34.246 1.00 29.39  ? 223 PHE D CG  1 
ATOM   6471  C  CD1 . PHE C 1 223 ? -40.097 35.420  -33.850 1.00 34.43  ? 223 PHE D CD1 1 
ATOM   6472  C  CD2 . PHE C 1 223 ? -37.751 35.727  -34.196 1.00 35.09  ? 223 PHE D CD2 1 
ATOM   6473  C  CE1 . PHE C 1 223 ? -39.868 34.126  -33.390 1.00 38.68  ? 223 PHE D CE1 1 
ATOM   6474  C  CE2 . PHE C 1 223 ? -37.504 34.445  -33.744 1.00 44.56  ? 223 PHE D CE2 1 
ATOM   6475  C  CZ  . PHE C 1 223 ? -38.569 33.637  -33.336 1.00 41.55  ? 223 PHE D CZ  1 
ATOM   6476  N  N   . THR C 1 224 ? -40.853 40.177  -34.883 1.00 24.37  ? 224 THR D N   1 
ATOM   6477  C  CA  . THR C 1 224 ? -40.620 41.587  -35.128 1.00 25.37  ? 224 THR D CA  1 
ATOM   6478  C  C   . THR C 1 224 ? -39.741 42.118  -34.002 1.00 24.99  ? 224 THR D C   1 
ATOM   6479  O  O   . THR C 1 224 ? -39.462 41.427  -33.018 1.00 27.76  ? 224 THR D O   1 
ATOM   6480  C  CB  . THR C 1 224 ? -41.938 42.364  -35.259 1.00 26.88  ? 224 THR D CB  1 
ATOM   6481  O  OG1 . THR C 1 224 ? -41.696 43.597  -35.955 1.00 22.64  ? 224 THR D OG1 1 
ATOM   6482  C  CG2 . THR C 1 224 ? -42.568 42.637  -33.888 1.00 21.23  ? 224 THR D CG2 1 
ATOM   6483  N  N   . THR C 1 225 ? -39.312 43.362  -34.141 1.00 26.24  ? 225 THR D N   1 
ATOM   6484  C  CA  . THR C 1 225 ? -38.427 43.967  -33.165 1.00 27.71  ? 225 THR D CA  1 
ATOM   6485  C  C   . THR C 1 225 ? -38.760 45.451  -33.100 1.00 22.43  ? 225 THR D C   1 
ATOM   6486  O  O   . THR C 1 225 ? -39.683 45.919  -33.762 1.00 22.50  ? 225 THR D O   1 
ATOM   6487  C  CB  . THR C 1 225 ? -36.953 43.682  -33.520 1.00 29.90  ? 225 THR D CB  1 
ATOM   6488  O  OG1 . THR C 1 225 ? -36.114 44.040  -32.418 1.00 27.40  ? 225 THR D OG1 1 
ATOM   6489  C  CG2 . THR C 1 225 ? -36.502 44.449  -34.787 1.00 24.33  ? 225 THR D CG2 1 
ATOM   6490  N  N   . THR C 1 226 ? -38.049 46.180  -32.246 1.00 25.78  ? 226 THR D N   1 
ATOM   6491  C  CA  . THR C 1 226 ? -38.143 47.632  -32.209 1.00 27.31  ? 226 THR D CA  1 
ATOM   6492  C  C   . THR C 1 226 ? -36.827 48.235  -32.670 1.00 27.63  ? 226 THR D C   1 
ATOM   6493  O  O   . THR C 1 226 ? -35.799 47.551  -32.772 1.00 25.91  ? 226 THR D O   1 
ATOM   6494  C  CB  . THR C 1 226 ? -38.491 48.176  -30.806 1.00 27.69  ? 226 THR D CB  1 
ATOM   6495  O  OG1 . THR C 1 226 ? -37.393 47.953  -29.910 1.00 26.92  ? 226 THR D OG1 1 
ATOM   6496  C  CG2 . THR C 1 226 ? -39.757 47.525  -30.236 1.00 21.43  ? 226 THR D CG2 1 
ATOM   6497  N  N   . LEU C 1 227 ? -36.895 49.528  -32.986 1.00 23.63  ? 227 LEU D N   1 
ATOM   6498  C  CA  . LEU C 1 227 ? -35.695 50.274  -33.331 1.00 25.74  ? 227 LEU D CA  1 
ATOM   6499  C  C   . LEU C 1 227 ? -34.672 50.203  -32.201 1.00 26.42  ? 227 LEU D C   1 
ATOM   6500  O  O   . LEU C 1 227 ? -33.473 50.022  -32.448 1.00 27.26  ? 227 LEU D O   1 
ATOM   6501  C  CB  . LEU C 1 227 ? -36.083 51.720  -33.658 1.00 24.75  ? 227 LEU D CB  1 
ATOM   6502  C  CG  . LEU C 1 227 ? -35.551 52.301  -34.968 1.00 26.35  ? 227 LEU D CG  1 
ATOM   6503  C  CD1 . LEU C 1 227 ? -35.703 51.282  -36.092 1.00 24.35  ? 227 LEU D CD1 1 
ATOM   6504  C  CD2 . LEU C 1 227 ? -36.283 53.588  -35.340 1.00 29.13  ? 227 LEU D CD2 1 
ATOM   6505  N  N   . ASN C 1 228 ? -35.132 50.281  -30.948 1.00 26.25  ? 228 ASN D N   1 
ATOM   6506  C  CA  . ASN C 1 228 ? -34.213 50.259  -29.810 1.00 28.37  ? 228 ASN D CA  1 
ATOM   6507  C  C   . ASN C 1 228 ? -33.519 48.909  -29.669 1.00 31.29  ? 228 ASN D C   1 
ATOM   6508  O  O   . ASN C 1 228 ? -32.296 48.841  -29.515 1.00 31.81  ? 228 ASN D O   1 
ATOM   6509  C  CB  . ASN C 1 228 ? -34.959 50.590  -28.516 1.00 31.18  ? 228 ASN D CB  1 
ATOM   6510  C  CG  . ASN C 1 228 ? -35.281 52.064  -28.378 1.00 37.37  ? 228 ASN D CG  1 
ATOM   6511  O  OD1 . ASN C 1 228 ? -35.005 52.877  -29.273 1.00 36.42  ? 228 ASN D OD1 1 
ATOM   6512  N  ND2 . ASN C 1 228 ? -35.851 52.426  -27.234 1.00 40.38  ? 228 ASN D ND2 1 
ATOM   6513  N  N   . ASP C 1 229 ? -34.289 47.821  -29.682 1.00 30.65  ? 229 ASP D N   1 
ATOM   6514  C  CA  . ASP C 1 229 ? -33.692 46.500  -29.518 1.00 30.98  ? 229 ASP D CA  1 
ATOM   6515  C  C   . ASP C 1 229 ? -32.802 46.149  -30.702 1.00 30.24  ? 229 ASP D C   1 
ATOM   6516  O  O   . ASP C 1 229 ? -31.770 45.493  -30.536 1.00 30.18  ? 229 ASP D O   1 
ATOM   6517  C  CB  . ASP C 1 229 ? -34.786 45.442  -29.348 1.00 37.41  ? 229 ASP D CB  1 
ATOM   6518  C  CG  . ASP C 1 229 ? -35.190 45.242  -27.892 1.00 47.52  ? 229 ASP D CG  1 
ATOM   6519  O  OD1 . ASP C 1 229 ? -34.907 46.138  -27.052 1.00 42.42  ? 229 ASP D OD1 1 
ATOM   6520  O  OD2 . ASP C 1 229 ? -35.787 44.178  -27.589 1.00 53.78  ? 229 ASP D OD2 1 
ATOM   6521  N  N   . PHE C 1 230 ? -33.185 46.580  -31.909 1.00 28.01  ? 230 PHE D N   1 
ATOM   6522  C  CA  . PHE C 1 230 ? -32.332 46.359  -33.070 1.00 30.11  ? 230 PHE D CA  1 
ATOM   6523  C  C   . PHE C 1 230 ? -31.009 47.107  -32.940 1.00 30.05  ? 230 PHE D C   1 
ATOM   6524  O  O   . PHE C 1 230 ? -29.939 46.563  -33.245 1.00 28.96  ? 230 PHE D O   1 
ATOM   6525  C  CB  . PHE C 1 230 ? -33.036 46.771  -34.364 1.00 26.99  ? 230 PHE D CB  1 
ATOM   6526  C  CG  . PHE C 1 230 ? -32.158 46.629  -35.560 1.00 25.53  ? 230 PHE D CG  1 
ATOM   6527  C  CD1 . PHE C 1 230 ? -31.975 45.384  -36.141 1.00 23.72  ? 230 PHE D CD1 1 
ATOM   6528  C  CD2 . PHE C 1 230 ? -31.468 47.732  -36.085 1.00 28.87  ? 230 PHE D CD2 1 
ATOM   6529  C  CE1 . PHE C 1 230 ? -31.142 45.234  -37.227 1.00 24.51  ? 230 PHE D CE1 1 
ATOM   6530  C  CE2 . PHE C 1 230 ? -30.637 47.595  -37.163 1.00 21.89  ? 230 PHE D CE2 1 
ATOM   6531  C  CZ  . PHE C 1 230 ? -30.469 46.348  -37.742 1.00 27.59  ? 230 PHE D CZ  1 
ATOM   6532  N  N   . ASN C 1 231 ? -31.061 48.370  -32.521 1.00 27.87  ? 231 ASN D N   1 
ATOM   6533  C  CA  . ASN C 1 231 ? -29.823 49.136  -32.445 1.00 27.20  ? 231 ASN D CA  1 
ATOM   6534  C  C   . ASN C 1 231 ? -28.899 48.604  -31.360 1.00 33.75  ? 231 ASN D C   1 
ATOM   6535  O  O   . ASN C 1 231 ? -27.668 48.668  -31.510 1.00 30.60  ? 231 ASN D O   1 
ATOM   6536  C  CB  . ASN C 1 231 ? -30.148 50.613  -32.236 1.00 25.27  ? 231 ASN D CB  1 
ATOM   6537  C  CG  . ASN C 1 231 ? -30.536 51.294  -33.526 1.00 26.70  ? 231 ASN D CG  1 
ATOM   6538  O  OD1 . ASN C 1 231 ? -29.965 51.001  -34.574 1.00 31.35  ? 231 ASN D OD1 1 
ATOM   6539  N  ND2 . ASN C 1 231 ? -31.545 52.150  -33.474 1.00 21.40  ? 231 ASN D ND2 1 
ATOM   6540  N  N   . LEU C 1 232 ? -29.470 48.022  -30.299 1.00 26.91  ? 232 LEU D N   1 
ATOM   6541  C  CA  . LEU C 1 232 ? -28.654 47.340  -29.307 1.00 26.40  ? 232 LEU D CA  1 
ATOM   6542  C  C   . LEU C 1 232 ? -27.799 46.269  -29.955 1.00 31.89  ? 232 LEU D C   1 
ATOM   6543  O  O   . LEU C 1 232 ? -26.629 46.101  -29.602 1.00 37.81  ? 232 LEU D O   1 
ATOM   6544  C  CB  . LEU C 1 232 ? -29.534 46.728  -28.225 1.00 32.17  ? 232 LEU D CB  1 
ATOM   6545  C  CG  . LEU C 1 232 ? -29.654 47.597  -26.982 1.00 34.50  ? 232 LEU D CG  1 
ATOM   6546  C  CD1 . LEU C 1 232 ? -30.110 46.767  -25.800 1.00 30.63  ? 232 LEU D CD1 1 
ATOM   6547  C  CD2 . LEU C 1 232 ? -28.337 48.318  -26.707 1.00 25.78  ? 232 LEU D CD2 1 
ATOM   6548  N  N   . VAL C 1 233 ? -28.383 45.511  -30.880 1.00 34.03  ? 233 VAL D N   1 
ATOM   6549  C  CA  . VAL C 1 233 ? -27.659 44.444  -31.559 1.00 36.55  ? 233 VAL D CA  1 
ATOM   6550  C  C   . VAL C 1 233 ? -26.766 45.006  -32.658 1.00 34.85  ? 233 VAL D C   1 
ATOM   6551  O  O   . VAL C 1 233 ? -25.590 44.646  -32.771 1.00 36.96  ? 233 VAL D O   1 
ATOM   6552  C  CB  . VAL C 1 233 ? -28.659 43.413  -32.112 1.00 37.40  ? 233 VAL D CB  1 
ATOM   6553  C  CG1 . VAL C 1 233 ? -27.930 42.205  -32.695 1.00 29.98  ? 233 VAL D CG1 1 
ATOM   6554  C  CG2 . VAL C 1 233 ? -29.647 43.007  -31.016 1.00 35.82  ? 233 VAL D CG2 1 
ATOM   6555  N  N   . ALA C 1 234 ? -27.312 45.900  -33.482 1.00 33.56  ? 234 ALA D N   1 
ATOM   6556  C  CA  . ALA C 1 234 ? -26.554 46.443  -34.602 1.00 35.38  ? 234 ALA D CA  1 
ATOM   6557  C  C   . ALA C 1 234 ? -25.266 47.120  -34.135 1.00 38.46  ? 234 ALA D C   1 
ATOM   6558  O  O   . ALA C 1 234 ? -24.235 47.041  -34.812 1.00 34.98  ? 234 ALA D O   1 
ATOM   6559  C  CB  . ALA C 1 234 ? -27.427 47.427  -35.380 1.00 39.36  ? 234 ALA D CB  1 
ATOM   6560  N  N   . MET C 1 235 ? -25.310 47.818  -32.997 1.00 35.68  ? 235 MET D N   1 
ATOM   6561  C  CA  . MET C 1 235 ? -24.115 48.506  -32.514 1.00 34.50  ? 235 MET D CA  1 
ATOM   6562  C  C   . MET C 1 235 ? -22.989 47.520  -32.191 1.00 38.73  ? 235 MET D C   1 
ATOM   6563  O  O   . MET C 1 235 ? -21.806 47.832  -32.387 1.00 37.45  ? 235 MET D O   1 
ATOM   6564  C  CB  . MET C 1 235 ? -24.466 49.365  -31.304 1.00 33.15  ? 235 MET D CB  1 
ATOM   6565  C  CG  . MET C 1 235 ? -23.291 50.168  -30.789 1.00 50.39  ? 235 MET D CG  1 
ATOM   6566  S  SD  . MET C 1 235 ? -23.686 51.275  -29.440 1.00 78.84  ? 235 MET D SD  1 
ATOM   6567  C  CE  . MET C 1 235 ? -24.468 52.618  -30.351 1.00 61.72  ? 235 MET D CE  1 
ATOM   6568  N  N   . LYS C 1 236 ? -23.332 46.343  -31.652 1.00 36.15  ? 236 LYS D N   1 
ATOM   6569  C  CA  . LYS C 1 236 ? -22.326 45.311  -31.407 1.00 37.77  ? 236 LYS D CA  1 
ATOM   6570  C  C   . LYS C 1 236 ? -21.630 44.874  -32.690 1.00 35.46  ? 236 LYS D C   1 
ATOM   6571  O  O   . LYS C 1 236 ? -20.443 44.531  -32.667 1.00 35.77  ? 236 LYS D O   1 
ATOM   6572  C  CB  . LYS C 1 236 ? -22.961 44.088  -30.740 1.00 37.34  ? 236 LYS D CB  1 
ATOM   6573  C  CG  . LYS C 1 236 ? -23.449 44.308  -29.322 1.00 45.64  ? 236 LYS D CG  1 
ATOM   6574  C  CD  . LYS C 1 236 ? -24.395 43.188  -28.865 1.00 46.60  ? 236 LYS D CD  1 
ATOM   6575  C  CE  . LYS C 1 236 ? -25.088 43.559  -27.559 1.00 50.50  ? 236 LYS D CE  1 
ATOM   6576  N  NZ  . LYS C 1 236 ? -26.340 42.782  -27.340 1.00 54.58  ? 236 LYS D NZ  1 
ATOM   6577  N  N   . TYR C 1 237 ? -22.342 44.863  -33.812 1.00 34.35  ? 237 TYR D N   1 
ATOM   6578  C  CA  . TYR C 1 237 ? -21.778 44.416  -35.080 1.00 31.05  ? 237 TYR D CA  1 
ATOM   6579  C  C   . TYR C 1 237 ? -21.325 45.576  -35.938 1.00 32.69  ? 237 TYR D C   1 
ATOM   6580  O  O   . TYR C 1 237 ? -21.137 45.407  -37.144 1.00 35.72  ? 237 TYR D O   1 
ATOM   6581  C  CB  . TYR C 1 237 ? -22.775 43.560  -35.861 1.00 27.86  ? 237 TYR D CB  1 
ATOM   6582  C  CG  . TYR C 1 237 ? -23.040 42.228  -35.199 1.00 39.88  ? 237 TYR D CG  1 
ATOM   6583  C  CD1 . TYR C 1 237 ? -24.025 42.093  -34.229 1.00 37.34  ? 237 TYR D CD1 1 
ATOM   6584  C  CD2 . TYR C 1 237 ? -22.251 41.118  -35.494 1.00 31.72  ? 237 TYR D CD2 1 
ATOM   6585  C  CE1 . TYR C 1 237 ? -24.251 40.878  -33.620 1.00 40.68  ? 237 TYR D CE1 1 
ATOM   6586  C  CE2 . TYR C 1 237 ? -22.465 39.925  -34.892 1.00 29.28  ? 237 TYR D CE2 1 
ATOM   6587  C  CZ  . TYR C 1 237 ? -23.461 39.797  -33.954 1.00 38.22  ? 237 TYR D CZ  1 
ATOM   6588  O  OH  . TYR C 1 237 ? -23.663 38.578  -33.338 1.00 36.58  ? 237 TYR D OH  1 
ATOM   6589  N  N   . ASN C 1 238 ? -21.176 46.755  -35.345 1.00 33.24  ? 238 ASN D N   1 
ATOM   6590  C  CA  . ASN C 1 238 ? -20.642 47.917  -36.045 1.00 34.95  ? 238 ASN D CA  1 
ATOM   6591  C  C   . ASN C 1 238 ? -21.540 48.292  -37.233 1.00 28.64  ? 238 ASN D C   1 
ATOM   6592  O  O   . ASN C 1 238 ? -21.077 48.691  -38.300 1.00 28.67  ? 238 ASN D O   1 
ATOM   6593  C  CB  . ASN C 1 238 ? -19.185 47.666  -36.457 1.00 34.19  ? 238 ASN D CB  1 
ATOM   6594  C  CG  . ASN C 1 238 ? -18.405 48.956  -36.677 1.00 40.62  ? 238 ASN D CG  1 
ATOM   6595  O  OD1 . ASN C 1 238 ? -18.743 50.003  -36.109 1.00 41.10  ? 238 ASN D OD1 1 
ATOM   6596  N  ND2 . ASN C 1 238 ? -17.336 48.882  -37.480 1.00 36.89  ? 238 ASN D ND2 1 
ATOM   6597  N  N   . TYR C 1 239 ? -22.847 48.169  -37.035 1.00 29.42  ? 239 TYR D N   1 
ATOM   6598  C  CA  . TYR C 1 239 ? -23.825 48.663  -37.985 1.00 25.95  ? 239 TYR D CA  1 
ATOM   6599  C  C   . TYR C 1 239 ? -24.215 50.073  -37.583 1.00 32.09  ? 239 TYR D C   1 
ATOM   6600  O  O   . TYR C 1 239 ? -24.258 50.396  -36.391 1.00 28.79  ? 239 TYR D O   1 
ATOM   6601  C  CB  . TYR C 1 239 ? -25.065 47.764  -38.035 1.00 25.28  ? 239 TYR D CB  1 
ATOM   6602  C  CG  . TYR C 1 239 ? -24.962 46.630  -39.046 1.00 26.81  ? 239 TYR D CG  1 
ATOM   6603  C  CD1 . TYR C 1 239 ? -23.919 45.718  -38.992 1.00 25.16  ? 239 TYR D CD1 1 
ATOM   6604  C  CD2 . TYR C 1 239 ? -25.893 46.501  -40.071 1.00 28.32  ? 239 TYR D CD2 1 
ATOM   6605  C  CE1 . TYR C 1 239 ? -23.813 44.687  -39.918 1.00 26.48  ? 239 TYR D CE1 1 
ATOM   6606  C  CE2 . TYR C 1 239 ? -25.794 45.486  -41.007 1.00 25.50  ? 239 TYR D CE2 1 
ATOM   6607  C  CZ  . TYR C 1 239 ? -24.747 44.579  -40.923 1.00 25.24  ? 239 TYR D CZ  1 
ATOM   6608  O  OH  . TYR C 1 239 ? -24.637 43.569  -41.848 1.00 24.11  ? 239 TYR D OH  1 
ATOM   6609  N  N   . GLU C 1 240 ? -24.434 50.909  -38.587 1.00 32.88  ? 240 GLU D N   1 
ATOM   6610  C  CA  . GLU C 1 240 ? -24.913 52.278  -38.312 1.00 32.01  ? 240 GLU D CA  1 
ATOM   6611  C  C   . GLU C 1 240 ? -26.269 52.181  -37.627 1.00 27.32  ? 240 GLU D C   1 
ATOM   6612  O  O   . GLU C 1 240 ? -27.106 51.375  -38.037 1.00 19.73  ? 240 GLU D O   1 
ATOM   6613  C  CB  . GLU C 1 240 ? -25.037 53.104  -39.591 1.00 33.77  ? 240 GLU D CB  1 
ATOM   6614  C  CG  . GLU C 1 240 ? -23.720 53.664  -40.084 1.00 43.78  ? 240 GLU D CG  1 
ATOM   6615  C  CD  . GLU C 1 240 ? -23.309 54.988  -39.465 1.00 51.18  ? 240 GLU D CD  1 
ATOM   6616  O  OE1 . GLU C 1 240 ? -24.199 55.796  -39.158 1.00 54.42  ? 240 GLU D OE1 1 
ATOM   6617  O  OE2 . GLU C 1 240 ? -22.099 55.205  -39.295 1.00 49.40  ? 240 GLU D OE2 1 
ATOM   6618  N  N   . PRO C 1 241 ? -26.512 53.007  -36.604 1.00 28.56  ? 241 PRO D N   1 
ATOM   6619  C  CA  . PRO C 1 241 ? -27.820 53.027  -35.948 1.00 23.78  ? 241 PRO D CA  1 
ATOM   6620  C  C   . PRO C 1 241 ? -28.905 53.303  -36.969 1.00 27.73  ? 241 PRO D C   1 
ATOM   6621  O  O   . PRO C 1 241 ? -28.733 54.127  -37.878 1.00 27.46  ? 241 PRO D O   1 
ATOM   6622  C  CB  . PRO C 1 241 ? -27.696 54.169  -34.938 1.00 30.17  ? 241 PRO D CB  1 
ATOM   6623  C  CG  . PRO C 1 241 ? -26.220 54.353  -34.741 1.00 24.02  ? 241 PRO D CG  1 
ATOM   6624  C  CD  . PRO C 1 241 ? -25.602 54.028  -36.068 1.00 23.11  ? 241 PRO D CD  1 
ATOM   6625  N  N   . LEU C 1 242 ? -30.010 52.569  -36.841 1.00 22.73  ? 242 LEU D N   1 
ATOM   6626  C  CA  . LEU C 1 242 ? -31.161 52.769  -37.704 1.00 27.48  ? 242 LEU D CA  1 
ATOM   6627  C  C   . LEU C 1 242 ? -32.078 53.830  -37.104 1.00 22.59  ? 242 LEU D C   1 
ATOM   6628  O  O   . LEU C 1 242 ? -32.455 53.738  -35.935 1.00 25.83  ? 242 LEU D O   1 
ATOM   6629  C  CB  . LEU C 1 242 ? -31.924 51.460  -37.907 1.00 27.45  ? 242 LEU D CB  1 
ATOM   6630  C  CG  . LEU C 1 242 ? -32.774 51.486  -39.171 1.00 27.17  ? 242 LEU D CG  1 
ATOM   6631  C  CD1 . LEU C 1 242 ? -31.813 51.361  -40.332 1.00 30.87  ? 242 LEU D CD1 1 
ATOM   6632  C  CD2 . LEU C 1 242 ? -33.799 50.369  -39.203 1.00 28.35  ? 242 LEU D CD2 1 
ATOM   6633  N  N   . THR C 1 243 ? -32.438 54.826  -37.907 1.00 22.89  ? 243 THR D N   1 
ATOM   6634  C  CA  . THR C 1 243 ? -33.284 55.934  -37.476 1.00 27.91  ? 243 THR D CA  1 
ATOM   6635  C  C   . THR C 1 243 ? -34.668 55.803  -38.094 1.00 26.69  ? 243 THR D C   1 
ATOM   6636  O  O   . THR C 1 243 ? -34.894 55.023  -39.024 1.00 26.05  ? 243 THR D O   1 
ATOM   6637  C  CB  . THR C 1 243 ? -32.703 57.296  -37.891 1.00 24.32  ? 243 THR D CB  1 
ATOM   6638  O  OG1 . THR C 1 243 ? -32.853 57.464  -39.305 1.00 22.80  ? 243 THR D OG1 1 
ATOM   6639  C  CG2 . THR C 1 243 ? -31.227 57.380  -37.555 1.00 31.07  ? 243 THR D CG2 1 
ATOM   6640  N  N   . GLN C 1 244 ? -35.592 56.631  -37.604 1.00 27.05  ? 244 GLN D N   1 
ATOM   6641  C  CA  . GLN C 1 244 ? -36.912 56.678  -38.222 1.00 24.53  ? 244 GLN D CA  1 
ATOM   6642  C  C   . GLN C 1 244 ? -36.834 57.173  -39.664 1.00 23.64  ? 244 GLN D C   1 
ATOM   6643  O  O   . GLN C 1 244 ? -37.560 56.670  -40.529 1.00 25.12  ? 244 GLN D O   1 
ATOM   6644  C  CB  . GLN C 1 244 ? -37.855 57.543  -37.368 1.00 28.26  ? 244 GLN D CB  1 
ATOM   6645  C  CG  . GLN C 1 244 ? -39.322 57.632  -37.870 1.00 26.05  ? 244 GLN D CG  1 
ATOM   6646  C  CD  . GLN C 1 244 ? -40.014 56.280  -37.984 1.00 27.44  ? 244 GLN D CD  1 
ATOM   6647  O  OE1 . GLN C 1 244 ? -39.819 55.397  -37.165 1.00 26.34  ? 244 GLN D OE1 1 
ATOM   6648  N  NE2 . GLN C 1 244 ? -40.785 56.107  -39.042 1.00 28.83  ? 244 GLN D NE2 1 
ATOM   6649  N  N   . ASP C 1 245 ? -35.912 58.090  -39.967 1.00 23.89  ? 245 ASP D N   1 
ATOM   6650  C  CA  . ASP C 1 245 ? -35.713 58.482  -41.363 1.00 31.81  ? 245 ASP D CA  1 
ATOM   6651  C  C   . ASP C 1 245 ? -35.373 57.286  -42.242 1.00 30.09  ? 245 ASP D C   1 
ATOM   6652  O  O   . ASP C 1 245 ? -35.864 57.180  -43.371 1.00 30.76  ? 245 ASP D O   1 
ATOM   6653  C  CB  . ASP C 1 245 ? -34.617 59.542  -41.494 1.00 39.30  ? 245 ASP D CB  1 
ATOM   6654  C  CG  . ASP C 1 245 ? -35.154 60.950  -41.343 1.00 52.86  ? 245 ASP D CG  1 
ATOM   6655  O  OD1 . ASP C 1 245 ? -36.251 61.095  -40.760 1.00 61.12  ? 245 ASP D OD1 1 
ATOM   6656  O  OD2 . ASP C 1 245 ? -34.525 61.905  -41.858 1.00 63.01  ? 245 ASP D OD2 1 
ATOM   6657  N  N   . HIS C 1 246 ? -34.543 56.373  -41.743 1.00 27.41  ? 246 HIS D N   1 
ATOM   6658  C  CA  . HIS C 1 246 ? -34.210 55.190  -42.527 1.00 26.41  ? 246 HIS D CA  1 
ATOM   6659  C  C   . HIS C 1 246 ? -35.435 54.315  -42.750 1.00 26.59  ? 246 HIS D C   1 
ATOM   6660  O  O   . HIS C 1 246 ? -35.675 53.838  -43.867 1.00 26.36  ? 246 HIS D O   1 
ATOM   6661  C  CB  . HIS C 1 246 ? -33.098 54.417  -41.823 1.00 29.27  ? 246 HIS D CB  1 
ATOM   6662  C  CG  . HIS C 1 246 ? -31.770 55.098  -41.902 1.00 29.65  ? 246 HIS D CG  1 
ATOM   6663  N  ND1 . HIS C 1 246 ? -30.819 54.999  -40.911 1.00 33.61  ? 246 HIS D ND1 1 
ATOM   6664  C  CD2 . HIS C 1 246 ? -31.249 55.914  -42.848 1.00 28.87  ? 246 HIS D CD2 1 
ATOM   6665  C  CE1 . HIS C 1 246 ? -29.758 55.708  -41.254 1.00 30.05  ? 246 HIS D CE1 1 
ATOM   6666  N  NE2 . HIS C 1 246 ? -29.994 56.273  -42.425 1.00 32.92  ? 246 HIS D NE2 1 
ATOM   6667  N  N   . VAL C 1 247 ? -36.230 54.103  -41.698 1.00 27.01  ? 247 VAL D N   1 
ATOM   6668  C  CA  . VAL C 1 247 ? -37.474 53.353  -41.842 1.00 28.20  ? 247 VAL D CA  1 
ATOM   6669  C  C   . VAL C 1 247 ? -38.363 54.002  -42.899 1.00 28.71  ? 247 VAL D C   1 
ATOM   6670  O  O   . VAL C 1 247 ? -38.921 53.322  -43.771 1.00 29.37  ? 247 VAL D O   1 
ATOM   6671  C  CB  . VAL C 1 247 ? -38.187 53.236  -40.481 1.00 27.61  ? 247 VAL D CB  1 
ATOM   6672  C  CG1 . VAL C 1 247 ? -39.483 52.486  -40.624 1.00 29.00  ? 247 VAL D CG1 1 
ATOM   6673  C  CG2 . VAL C 1 247 ? -37.291 52.546  -39.482 1.00 27.13  ? 247 VAL D CG2 1 
ATOM   6674  N  N   . ASP C 1 248 ? -38.495 55.330  -42.851 1.00 29.72  ? 248 ASP D N   1 
ATOM   6675  C  CA  . ASP C 1 248 ? -39.322 56.021  -43.840 1.00 25.28  ? 248 ASP D CA  1 
ATOM   6676  C  C   . ASP C 1 248 ? -38.779 55.801  -45.248 1.00 27.39  ? 248 ASP D C   1 
ATOM   6677  O  O   . ASP C 1 248 ? -39.542 55.562  -46.193 1.00 31.59  ? 248 ASP D O   1 
ATOM   6678  C  CB  . ASP C 1 248 ? -39.373 57.521  -43.524 1.00 27.83  ? 248 ASP D CB  1 
ATOM   6679  C  CG  . ASP C 1 248 ? -40.024 57.827  -42.180 1.00 30.97  ? 248 ASP D CG  1 
ATOM   6680  O  OD1 . ASP C 1 248 ? -40.932 57.072  -41.781 1.00 31.28  ? 248 ASP D OD1 1 
ATOM   6681  O  OD2 . ASP C 1 248 ? -39.609 58.805  -41.501 1.00 33.42  ? 248 ASP D OD2 1 
ATOM   6682  N  N   . ILE C 1 249 ? -37.459 55.861  -45.401 1.00 22.53  ? 249 ILE D N   1 
ATOM   6683  C  CA  . ILE C 1 249 ? -36.844 55.689  -46.711 1.00 27.02  ? 249 ILE D CA  1 
ATOM   6684  C  C   . ILE C 1 249 ? -37.140 54.295  -47.266 1.00 27.00  ? 249 ILE D C   1 
ATOM   6685  O  O   . ILE C 1 249 ? -37.423 54.130  -48.460 1.00 26.01  ? 249 ILE D O   1 
ATOM   6686  C  CB  . ILE C 1 249 ? -35.328 55.972  -46.606 1.00 25.25  ? 249 ILE D CB  1 
ATOM   6687  C  CG1 . ILE C 1 249 ? -35.081 57.481  -46.455 1.00 26.73  ? 249 ILE D CG1 1 
ATOM   6688  C  CG2 . ILE C 1 249 ? -34.584 55.456  -47.827 1.00 29.75  ? 249 ILE D CG2 1 
ATOM   6689  C  CD1 . ILE C 1 249 ? -33.707 57.846  -45.936 1.00 24.64  ? 249 ILE D CD1 1 
ATOM   6690  N  N   . LEU C 1 250 ? -37.145 53.279  -46.396 1.00 28.52  ? 250 LEU D N   1 
ATOM   6691  C  CA  . LEU C 1 250 ? -37.445 51.912  -46.822 1.00 29.04  ? 250 LEU D CA  1 
ATOM   6692  C  C   . LEU C 1 250 ? -38.932 51.679  -47.129 1.00 29.40  ? 250 LEU D C   1 
ATOM   6693  O  O   . LEU C 1 250 ? -39.287 50.569  -47.528 1.00 33.23  ? 250 LEU D O   1 
ATOM   6694  C  CB  . LEU C 1 250 ? -36.969 50.920  -45.757 1.00 26.21  ? 250 LEU D CB  1 
ATOM   6695  C  CG  . LEU C 1 250 ? -35.455 50.707  -45.580 1.00 25.28  ? 250 LEU D CG  1 
ATOM   6696  C  CD1 . LEU C 1 250 ? -35.157 49.930  -44.286 1.00 22.66  ? 250 LEU D CD1 1 
ATOM   6697  C  CD2 . LEU C 1 250 ? -34.774 50.050  -46.777 1.00 23.76  ? 250 LEU D CD2 1 
ATOM   6698  N  N   . GLY C 1 251 ? -39.802 52.674  -46.962 1.00 31.52  ? 251 GLY D N   1 
ATOM   6699  C  CA  . GLY C 1 251 ? -41.220 52.533  -47.220 1.00 26.07  ? 251 GLY D CA  1 
ATOM   6700  C  C   . GLY C 1 251 ? -41.608 51.870  -48.543 1.00 31.95  ? 251 GLY D C   1 
ATOM   6701  O  O   . GLY C 1 251 ? -42.418 50.930  -48.576 1.00 32.82  ? 251 GLY D O   1 
ATOM   6702  N  N   . PRO C 1 252 ? -41.111 52.391  -49.667 1.00 24.61  ? 252 PRO D N   1 
ATOM   6703  C  CA  . PRO C 1 252 ? -41.477 51.772  -50.956 1.00 24.12  ? 252 PRO D CA  1 
ATOM   6704  C  C   . PRO C 1 252 ? -41.145 50.287  -51.055 1.00 25.54  ? 252 PRO D C   1 
ATOM   6705  O  O   . PRO C 1 252 ? -41.969 49.510  -51.560 1.00 25.90  ? 252 PRO D O   1 
ATOM   6706  C  CB  . PRO C 1 252 ? -40.682 52.600  -51.972 1.00 19.27  ? 252 PRO D CB  1 
ATOM   6707  C  CG  . PRO C 1 252 ? -40.534 53.930  -51.314 1.00 19.01  ? 252 PRO D CG  1 
ATOM   6708  C  CD  . PRO C 1 252 ? -40.394 53.664  -49.843 1.00 24.49  ? 252 PRO D CD  1 
ATOM   6709  N  N   . LEU C 1 253 ? -39.962 49.865  -50.591 1.00 25.09  ? 253 LEU D N   1 
ATOM   6710  C  CA  . LEU C 1 253 ? -39.604 48.446  -50.642 1.00 24.33  ? 253 LEU D CA  1 
ATOM   6711  C  C   . LEU C 1 253 ? -40.447 47.625  -49.668 1.00 27.01  ? 253 LEU D C   1 
ATOM   6712  O  O   . LEU C 1 253 ? -40.789 46.469  -49.952 1.00 27.69  ? 253 LEU D O   1 
ATOM   6713  C  CB  . LEU C 1 253 ? -38.107 48.281  -50.340 1.00 22.69  ? 253 LEU D CB  1 
ATOM   6714  C  CG  . LEU C 1 253 ? -37.146 48.772  -51.439 1.00 28.90  ? 253 LEU D CG  1 
ATOM   6715  C  CD1 . LEU C 1 253 ? -35.654 48.726  -50.997 1.00 21.86  ? 253 LEU D CD1 1 
ATOM   6716  C  CD2 . LEU C 1 253 ? -37.378 47.981  -52.739 1.00 24.94  ? 253 LEU D CD2 1 
ATOM   6717  N  N   . SER C 1 254 ? -40.784 48.212  -48.522 1.00 26.01  ? 254 SER D N   1 
ATOM   6718  C  CA  . SER C 1 254 ? -41.640 47.557  -47.549 1.00 26.28  ? 254 SER D CA  1 
ATOM   6719  C  C   . SER C 1 254 ? -43.043 47.349  -48.107 1.00 29.50  ? 254 SER D C   1 
ATOM   6720  O  O   . SER C 1 254 ? -43.670 46.311  -47.856 1.00 25.81  ? 254 SER D O   1 
ATOM   6721  C  CB  . SER C 1 254 ? -41.673 48.384  -46.265 1.00 26.22  ? 254 SER D CB  1 
ATOM   6722  O  OG  . SER C 1 254 ? -42.550 47.790  -45.322 1.00 31.15  ? 254 SER D OG  1 
ATOM   6723  N  N   . ALA C 1 255 ? -43.565 48.342  -48.846 1.00 29.61  ? 255 ALA D N   1 
ATOM   6724  C  CA  . ALA C 1 255 ? -44.896 48.213  -49.437 1.00 29.02  ? 255 ALA D CA  1 
ATOM   6725  C  C   . ALA C 1 255 ? -44.900 47.215  -50.598 1.00 32.43  ? 255 ALA D C   1 
ATOM   6726  O  O   . ALA C 1 255 ? -45.806 46.376  -50.707 1.00 35.49  ? 255 ALA D O   1 
ATOM   6727  C  CB  . ALA C 1 255 ? -45.390 49.583  -49.899 1.00 25.87  ? 255 ALA D CB  1 
ATOM   6728  N  N   . GLN C 1 256 ? -43.866 47.242  -51.439 1.00 29.48  ? 256 GLN D N   1 
ATOM   6729  C  CA  . GLN C 1 256 ? -43.832 46.337  -52.576 1.00 29.64  ? 256 GLN D CA  1 
ATOM   6730  C  C   . GLN C 1 256 ? -43.841 44.882  -52.128 1.00 30.11  ? 256 GLN D C   1 
ATOM   6731  O  O   . GLN C 1 256 ? -44.485 44.045  -52.768 1.00 28.41  ? 256 GLN D O   1 
ATOM   6732  C  CB  . GLN C 1 256 ? -42.607 46.644  -53.439 1.00 32.47  ? 256 GLN D CB  1 
ATOM   6733  C  CG  . GLN C 1 256 ? -42.262 45.586  -54.495 1.00 34.45  ? 256 GLN D CG  1 
ATOM   6734  C  CD  . GLN C 1 256 ? -41.242 46.111  -55.498 1.00 42.22  ? 256 GLN D CD  1 
ATOM   6735  O  OE1 . GLN C 1 256 ? -40.808 47.269  -55.413 1.00 39.57  ? 256 GLN D OE1 1 
ATOM   6736  N  NE2 . GLN C 1 256 ? -40.854 45.266  -56.454 1.00 41.92  ? 256 GLN D NE2 1 
ATOM   6737  N  N   . THR C 1 257 ? -43.215 44.579  -50.985 1.00 30.74  ? 257 THR D N   1 
ATOM   6738  C  CA  . THR C 1 257 ? -43.185 43.216  -50.463 1.00 29.81  ? 257 THR D CA  1 
ATOM   6739  C  C   . THR C 1 257 ? -44.266 42.937  -49.428 1.00 30.77  ? 257 THR D C   1 
ATOM   6740  O  O   . THR C 1 257 ? -44.674 41.785  -49.287 1.00 33.15  ? 257 THR D O   1 
ATOM   6741  C  CB  . THR C 1 257 ? -41.829 42.913  -49.808 1.00 28.91  ? 257 THR D CB  1 
ATOM   6742  O  OG1 . THR C 1 257 ? -41.583 43.843  -48.741 1.00 24.58  ? 257 THR D OG1 1 
ATOM   6743  C  CG2 . THR C 1 257 ? -40.706 42.995  -50.831 1.00 24.41  ? 257 THR D CG2 1 
ATOM   6744  N  N   . GLY C 1 258 ? -44.794 43.953  -48.757 1.00 28.07  ? 258 GLY D N   1 
ATOM   6745  C  CA  . GLY C 1 258 ? -45.700 43.689  -47.663 1.00 28.74  ? 258 GLY D CA  1 
ATOM   6746  C  C   . GLY C 1 258 ? -45.022 43.162  -46.423 1.00 29.43  ? 258 GLY D C   1 
ATOM   6747  O  O   . GLY C 1 258 ? -45.681 42.544  -45.586 1.00 36.27  ? 258 GLY D O   1 
ATOM   6748  N  N   . ILE C 1 259 ? -43.721 43.402  -46.271 1.00 29.89  ? 259 ILE D N   1 
ATOM   6749  C  CA  . ILE C 1 259 ? -42.972 43.034  -45.076 1.00 27.09  ? 259 ILE D CA  1 
ATOM   6750  C  C   . ILE C 1 259 ? -42.611 44.332  -44.375 1.00 28.80  ? 259 ILE D C   1 
ATOM   6751  O  O   . ILE C 1 259 ? -41.837 45.136  -44.911 1.00 31.04  ? 259 ILE D O   1 
ATOM   6752  C  CB  . ILE C 1 259 ? -41.713 42.223  -45.419 1.00 27.79  ? 259 ILE D CB  1 
ATOM   6753  C  CG1 . ILE C 1 259 ? -42.086 40.937  -46.144 1.00 24.02  ? 259 ILE D CG1 1 
ATOM   6754  C  CG2 . ILE C 1 259 ? -40.857 41.974  -44.181 1.00 23.50  ? 259 ILE D CG2 1 
ATOM   6755  C  CD1 . ILE C 1 259 ? -40.931 40.269  -46.780 1.00 24.65  ? 259 ILE D CD1 1 
ATOM   6756  N  N   . ALA C 1 260 ? -43.157 44.543  -43.180 1.00 26.12  ? 260 ALA D N   1 
ATOM   6757  C  CA  . ALA C 1 260 ? -42.858 45.768  -42.454 1.00 23.40  ? 260 ALA D CA  1 
ATOM   6758  C  C   . ALA C 1 260 ? -41.363 45.841  -42.163 1.00 27.04  ? 260 ALA D C   1 
ATOM   6759  O  O   . ALA C 1 260 ? -40.694 44.818  -41.964 1.00 27.23  ? 260 ALA D O   1 
ATOM   6760  C  CB  . ALA C 1 260 ? -43.654 45.840  -41.155 1.00 15.33  ? 260 ALA D CB  1 
ATOM   6761  N  N   . VAL C 1 261 ? -40.851 47.075  -42.112 1.00 23.11  ? 261 VAL D N   1 
ATOM   6762  C  CA  . VAL C 1 261 ? -39.416 47.287  -41.979 1.00 20.13  ? 261 VAL D CA  1 
ATOM   6763  C  C   . VAL C 1 261 ? -38.905 46.679  -40.678 1.00 24.02  ? 261 VAL D C   1 
ATOM   6764  O  O   . VAL C 1 261 ? -37.869 46.000  -40.661 1.00 21.90  ? 261 VAL D O   1 
ATOM   6765  C  CB  . VAL C 1 261 ? -39.097 48.797  -42.074 1.00 21.38  ? 261 VAL D CB  1 
ATOM   6766  C  CG1 . VAL C 1 261 ? -37.645 49.084  -41.703 1.00 18.46  ? 261 VAL D CG1 1 
ATOM   6767  C  CG2 . VAL C 1 261 ? -39.409 49.317  -43.462 1.00 23.07  ? 261 VAL D CG2 1 
ATOM   6768  N  N   . LEU C 1 262 ? -39.632 46.874  -39.574 1.00 18.72  ? 262 LEU D N   1 
ATOM   6769  C  CA  . LEU C 1 262 ? -39.210 46.256  -38.324 1.00 21.66  ? 262 LEU D CA  1 
ATOM   6770  C  C   . LEU C 1 262 ? -39.331 44.734  -38.374 1.00 23.42  ? 262 LEU D C   1 
ATOM   6771  O  O   . LEU C 1 262 ? -38.626 44.037  -37.629 1.00 21.51  ? 262 LEU D O   1 
ATOM   6772  C  CB  . LEU C 1 262 ? -40.005 46.827  -37.140 1.00 20.71  ? 262 LEU D CB  1 
ATOM   6773  C  CG  . LEU C 1 262 ? -39.672 48.281  -36.764 1.00 23.86  ? 262 LEU D CG  1 
ATOM   6774  C  CD1 . LEU C 1 262 ? -40.593 48.813  -35.669 1.00 23.15  ? 262 LEU D CD1 1 
ATOM   6775  C  CD2 . LEU C 1 262 ? -38.226 48.396  -36.314 1.00 23.71  ? 262 LEU D CD2 1 
ATOM   6776  N  N   . ASP C 1 263 ? -40.201 44.190  -39.228 1.00 23.19  ? 263 ASP D N   1 
ATOM   6777  C  CA  . ASP C 1 263 ? -40.161 42.742  -39.411 1.00 26.11  ? 263 ASP D CA  1 
ATOM   6778  C  C   . ASP C 1 263 ? -38.872 42.331  -40.126 1.00 25.50  ? 263 ASP D C   1 
ATOM   6779  O  O   . ASP C 1 263 ? -38.242 41.330  -39.757 1.00 24.76  ? 263 ASP D O   1 
ATOM   6780  C  CB  . ASP C 1 263 ? -41.397 42.252  -40.168 1.00 25.42  ? 263 ASP D CB  1 
ATOM   6781  C  CG  . ASP C 1 263 ? -42.673 42.382  -39.360 1.00 23.81  ? 263 ASP D CG  1 
ATOM   6782  O  OD1 . ASP C 1 263 ? -42.617 42.904  -38.233 1.00 27.27  ? 263 ASP D OD1 1 
ATOM   6783  O  OD2 . ASP C 1 263 ? -43.738 41.949  -39.846 1.00 24.54  ? 263 ASP D OD2 1 
ATOM   6784  N  N   . MET C 1 264 ? -38.468 43.092  -41.153 1.00 22.06  ? 264 MET D N   1 
ATOM   6785  C  CA  . MET C 1 264 ? -37.209 42.813  -41.840 1.00 21.05  ? 264 MET D CA  1 
ATOM   6786  C  C   . MET C 1 264 ? -36.009 43.014  -40.925 1.00 19.45  ? 264 MET D C   1 
ATOM   6787  O  O   . MET C 1 264 ? -35.006 42.295  -41.053 1.00 20.72  ? 264 MET D O   1 
ATOM   6788  C  CB  . MET C 1 264 ? -37.085 43.673  -43.106 1.00 15.96  ? 264 MET D CB  1 
ATOM   6789  C  CG  . MET C 1 264 ? -35.880 43.297  -43.973 1.00 25.54  ? 264 MET D CG  1 
ATOM   6790  S  SD  . MET C 1 264 ? -35.963 41.614  -44.705 1.00 22.85  ? 264 MET D SD  1 
ATOM   6791  C  CE  . MET C 1 264 ? -37.033 41.927  -46.118 1.00 21.98  ? 264 MET D CE  1 
ATOM   6792  N  N   . CYS C 1 265 ? -36.083 44.000  -40.013 1.00 21.12  ? 265 CYS D N   1 
ATOM   6793  C  CA  . CYS C 1 265 ? -35.024 44.208  -39.026 1.00 15.85  ? 265 CYS D CA  1 
ATOM   6794  C  C   . CYS C 1 265 ? -34.845 42.972  -38.148 1.00 23.46  ? 265 CYS D C   1 
ATOM   6795  O  O   . CYS C 1 265 ? -33.715 42.614  -37.780 1.00 20.85  ? 265 CYS D O   1 
ATOM   6796  C  CB  . CYS C 1 265 ? -35.333 45.427  -38.160 1.00 17.18  ? 265 CYS D CB  1 
ATOM   6797  S  SG  . CYS C 1 265 ? -35.148 47.061  -38.931 1.00 24.16  ? 265 CYS D SG  1 
ATOM   6798  N  N   . ALA C 1 266 ? -35.952 42.301  -37.808 1.00 19.43  ? 266 ALA D N   1 
ATOM   6799  C  CA  . ALA C 1 266 ? -35.850 41.084  -37.019 1.00 21.78  ? 266 ALA D CA  1 
ATOM   6800  C  C   . ALA C 1 266 ? -35.097 39.979  -37.765 1.00 27.40  ? 266 ALA D C   1 
ATOM   6801  O  O   . ALA C 1 266 ? -34.370 39.206  -37.137 1.00 26.34  ? 266 ALA D O   1 
ATOM   6802  C  CB  . ALA C 1 266 ? -37.242 40.612  -36.617 1.00 23.37  ? 266 ALA D CB  1 
ATOM   6803  N  N   . SER C 1 267 ? -35.226 39.900  -39.098 1.00 27.19  ? 267 SER D N   1 
ATOM   6804  C  CA  . SER C 1 267 ? -34.449 38.900  -39.838 1.00 27.40  ? 267 SER D CA  1 
ATOM   6805  C  C   . SER C 1 267 ? -32.972 39.247  -39.846 1.00 26.01  ? 267 SER D C   1 
ATOM   6806  O  O   . SER C 1 267 ? -32.117 38.353  -39.754 1.00 25.45  ? 267 SER D O   1 
ATOM   6807  C  CB  . SER C 1 267 ? -34.955 38.762  -41.274 1.00 28.69  ? 267 SER D CB  1 
ATOM   6808  O  OG  . SER C 1 267 ? -36.166 38.039  -41.318 1.00 31.87  ? 267 SER D OG  1 
ATOM   6809  N  N   . LEU C 1 268 ? -32.655 40.537  -40.001 1.00 23.03  ? 268 LEU D N   1 
ATOM   6810  C  CA  . LEU C 1 268 ? -31.263 40.975  -39.961 1.00 21.36  ? 268 LEU D CA  1 
ATOM   6811  C  C   . LEU C 1 268 ? -30.659 40.734  -38.588 1.00 24.10  ? 268 LEU D C   1 
ATOM   6812  O  O   . LEU C 1 268 ? -29.496 40.317  -38.471 1.00 24.66  ? 268 LEU D O   1 
ATOM   6813  C  CB  . LEU C 1 268 ? -31.174 42.453  -40.345 1.00 20.78  ? 268 LEU D CB  1 
ATOM   6814  C  CG  . LEU C 1 268 ? -29.817 43.148  -40.378 1.00 22.77  ? 268 LEU D CG  1 
ATOM   6815  C  CD1 . LEU C 1 268 ? -28.862 42.388  -41.263 1.00 17.35  ? 268 LEU D CD1 1 
ATOM   6816  C  CD2 . LEU C 1 268 ? -30.011 44.552  -40.922 1.00 21.86  ? 268 LEU D CD2 1 
ATOM   6817  N  N   . LYS C 1 269 ? -31.435 41.007  -37.536 1.00 24.87  ? 269 LYS D N   1 
ATOM   6818  C  CA  . LYS C 1 269 ? -31.003 40.721  -36.170 1.00 29.22  ? 269 LYS D CA  1 
ATOM   6819  C  C   . LYS C 1 269 ? -30.599 39.260  -36.015 1.00 27.32  ? 269 LYS D C   1 
ATOM   6820  O  O   . LYS C 1 269 ? -29.529 38.950  -35.484 1.00 27.88  ? 269 LYS D O   1 
ATOM   6821  C  CB  . LYS C 1 269 ? -32.132 41.088  -35.206 1.00 31.17  ? 269 LYS D CB  1 
ATOM   6822  C  CG  . LYS C 1 269 ? -31.913 40.777  -33.752 1.00 32.72  ? 269 LYS D CG  1 
ATOM   6823  C  CD  . LYS C 1 269 ? -32.838 41.703  -32.955 1.00 36.90  ? 269 LYS D CD  1 
ATOM   6824  C  CE  . LYS C 1 269 ? -33.369 41.090  -31.674 1.00 43.90  ? 269 LYS D CE  1 
ATOM   6825  N  NZ  . LYS C 1 269 ? -34.573 41.864  -31.189 1.00 34.16  ? 269 LYS D NZ  1 
ATOM   6826  N  N   . GLU C 1 270 ? -31.435 38.350  -36.504 1.00 25.86  ? 270 GLU D N   1 
ATOM   6827  C  CA  . GLU C 1 270 ? -31.108 36.932  -36.413 1.00 32.03  ? 270 GLU D CA  1 
ATOM   6828  C  C   . GLU C 1 270 ? -30.005 36.545  -37.393 1.00 29.47  ? 270 GLU D C   1 
ATOM   6829  O  O   . GLU C 1 270 ? -29.131 35.735  -37.057 1.00 27.21  ? 270 GLU D O   1 
ATOM   6830  C  CB  . GLU C 1 270 ? -32.375 36.094  -36.600 1.00 31.37  ? 270 GLU D CB  1 
ATOM   6831  C  CG  . GLU C 1 270 ? -33.304 36.226  -35.385 1.00 32.50  ? 270 GLU D CG  1 
ATOM   6832  C  CD  . GLU C 1 270 ? -32.640 35.731  -34.098 1.00 47.90  ? 270 GLU D CD  1 
ATOM   6833  O  OE1 . GLU C 1 270 ? -32.153 34.573  -34.087 1.00 46.17  ? 270 GLU D OE1 1 
ATOM   6834  O  OE2 . GLU C 1 270 ? -32.554 36.509  -33.115 1.00 47.91  ? 270 GLU D OE2 1 
ATOM   6835  N  N   . LEU C 1 271 ? -30.007 37.120  -38.600 1.00 28.89  ? 271 LEU D N   1 
ATOM   6836  C  CA  . LEU C 1 271 ? -28.880 36.880  -39.501 1.00 31.06  ? 271 LEU D CA  1 
ATOM   6837  C  C   . LEU C 1 271 ? -27.569 37.311  -38.859 1.00 28.86  ? 271 LEU D C   1 
ATOM   6838  O  O   . LEU C 1 271 ? -26.581 36.568  -38.894 1.00 28.85  ? 271 LEU D O   1 
ATOM   6839  C  CB  . LEU C 1 271 ? -29.083 37.581  -40.844 1.00 28.79  ? 271 LEU D CB  1 
ATOM   6840  C  CG  . LEU C 1 271 ? -29.966 36.834  -41.836 1.00 25.36  ? 271 LEU D CG  1 
ATOM   6841  C  CD1 . LEU C 1 271 ? -30.191 37.737  -43.054 1.00 29.68  ? 271 LEU D CD1 1 
ATOM   6842  C  CD2 . LEU C 1 271 ? -29.275 35.563  -42.250 1.00 20.26  ? 271 LEU D CD2 1 
ATOM   6843  N  N   . LEU C 1 272 ? -27.550 38.505  -38.247 1.00 28.33  ? 272 LEU D N   1 
ATOM   6844  C  CA  . LEU C 1 272 ? -26.342 38.978  -37.571 1.00 27.18  ? 272 LEU D CA  1 
ATOM   6845  C  C   . LEU C 1 272 ? -25.951 38.065  -36.404 1.00 28.30  ? 272 LEU D C   1 
ATOM   6846  O  O   . LEU C 1 272 ? -24.774 37.741  -36.222 1.00 29.97  ? 272 LEU D O   1 
ATOM   6847  C  CB  . LEU C 1 272 ? -26.551 40.411  -37.087 1.00 27.10  ? 272 LEU D CB  1 
ATOM   6848  C  CG  . LEU C 1 272 ? -26.456 41.460  -38.203 1.00 30.97  ? 272 LEU D CG  1 
ATOM   6849  C  CD1 . LEU C 1 272 ? -26.825 42.896  -37.740 1.00 22.31  ? 272 LEU D CD1 1 
ATOM   6850  C  CD2 . LEU C 1 272 ? -25.071 41.421  -38.842 1.00 28.28  ? 272 LEU D CD2 1 
ATOM   6851  N  N   . GLN C 1 273 ? -26.927 37.592  -35.635 1.00 30.60  ? 273 GLN D N   1 
ATOM   6852  C  CA  . GLN C 1 273 ? -26.602 36.884  -34.401 1.00 33.02  ? 273 GLN D CA  1 
ATOM   6853  C  C   . GLN C 1 273 ? -26.192 35.438  -34.649 1.00 30.29  ? 273 GLN D C   1 
ATOM   6854  O  O   . GLN C 1 273 ? -25.427 34.881  -33.861 1.00 25.16  ? 273 GLN D O   1 
ATOM   6855  C  CB  . GLN C 1 273 ? -27.772 36.975  -33.421 1.00 29.42  ? 273 GLN D CB  1 
ATOM   6856  C  CG  . GLN C 1 273 ? -27.845 38.371  -32.816 1.00 36.44  ? 273 GLN D CG  1 
ATOM   6857  C  CD  . GLN C 1 273 ? -29.019 38.593  -31.894 1.00 35.01  ? 273 GLN D CD  1 
ATOM   6858  O  OE1 . GLN C 1 273 ? -30.085 38.001  -32.054 1.00 40.76  ? 273 GLN D OE1 1 
ATOM   6859  N  NE2 . GLN C 1 273 ? -28.819 39.449  -30.908 1.00 35.25  ? 273 GLN D NE2 1 
ATOM   6860  N  N   . ASN C 1 274 ? -26.699 34.820  -35.710 1.00 33.15  ? 274 ASN D N   1 
ATOM   6861  C  CA  . ASN C 1 274 ? -26.418 33.426  -36.022 1.00 27.22  ? 274 ASN D CA  1 
ATOM   6862  C  C   . ASN C 1 274 ? -25.626 33.236  -37.312 1.00 31.67  ? 274 ASN D C   1 
ATOM   6863  O  O   . ASN C 1 274 ? -25.385 32.094  -37.712 1.00 30.51  ? 274 ASN D O   1 
ATOM   6864  C  CB  . ASN C 1 274 ? -27.737 32.660  -36.107 1.00 31.39  ? 274 ASN D CB  1 
ATOM   6865  C  CG  . ASN C 1 274 ? -28.650 32.983  -34.952 1.00 36.55  ? 274 ASN D CG  1 
ATOM   6866  O  OD1 . ASN C 1 274 ? -29.829 33.303  -35.150 1.00 40.86  ? 274 ASN D OD1 1 
ATOM   6867  N  ND2 . ASN C 1 274 ? -28.105 32.956  -33.737 1.00 35.11  ? 274 ASN D ND2 1 
ATOM   6868  N  N   . GLY C 1 275 ? -25.220 34.316  -37.979 1.00 35.93  ? 275 GLY D N   1 
ATOM   6869  C  CA  . GLY C 1 275 ? -24.521 34.170  -39.231 1.00 30.27  ? 275 GLY D CA  1 
ATOM   6870  C  C   . GLY C 1 275 ? -25.429 33.612  -40.312 1.00 29.18  ? 275 GLY D C   1 
ATOM   6871  O  O   . GLY C 1 275 ? -26.650 33.536  -40.183 1.00 31.89  ? 275 GLY D O   1 
ATOM   6872  N  N   . MET C 1 276 ? -24.796 33.231  -41.412 1.00 32.21  ? 276 MET D N   1 
ATOM   6873  C  CA  . MET C 1 276 ? -25.522 32.737  -42.569 1.00 38.87  ? 276 MET D CA  1 
ATOM   6874  C  C   . MET C 1 276 ? -25.395 31.234  -42.759 1.00 28.94  ? 276 MET D C   1 
ATOM   6875  O  O   . MET C 1 276 ? -26.006 30.698  -43.684 1.00 32.03  ? 276 MET D O   1 
ATOM   6876  C  CB  . MET C 1 276 ? -25.096 33.478  -43.846 1.00 36.02  ? 276 MET D CB  1 
ATOM   6877  C  CG  . MET C 1 276 ? -25.641 34.904  -43.927 1.00 31.40  ? 276 MET D CG  1 
ATOM   6878  S  SD  . MET C 1 276 ? -25.395 35.643  -45.556 1.00 45.70  ? 276 MET D SD  1 
ATOM   6879  C  CE  . MET C 1 276 ? -26.260 34.475  -46.574 1.00 38.45  ? 276 MET D CE  1 
ATOM   6880  N  N   . ASN C 1 277 ? -24.624 30.548  -41.917 1.00 35.00  ? 277 ASN D N   1 
ATOM   6881  C  CA  . ASN C 1 277 ? -24.632 29.080  -41.868 1.00 35.30  ? 277 ASN D CA  1 
ATOM   6882  C  C   . ASN C 1 277 ? -24.314 28.477  -43.230 1.00 37.33  ? 277 ASN D C   1 
ATOM   6883  O  O   . ASN C 1 277 ? -24.979 27.544  -43.684 1.00 34.44  ? 277 ASN D O   1 
ATOM   6884  C  CB  . ASN C 1 277 ? -25.982 28.554  -41.375 1.00 35.56  ? 277 ASN D CB  1 
ATOM   6885  C  CG  . ASN C 1 277 ? -26.234 28.853  -39.920 1.00 39.32  ? 277 ASN D CG  1 
ATOM   6886  O  OD1 . ASN C 1 277 ? -27.326 29.286  -39.536 1.00 42.96  ? 277 ASN D OD1 1 
ATOM   6887  N  ND2 . ASN C 1 277 ? -25.238 28.605  -39.093 1.00 35.97  ? 277 ASN D ND2 1 
ATOM   6888  N  N   . GLY C 1 278 ? -23.310 29.035  -43.901 1.00 36.85  ? 278 GLY D N   1 
ATOM   6889  C  CA  . GLY C 1 278 ? -22.918 28.556  -45.204 1.00 32.35  ? 278 GLY D CA  1 
ATOM   6890  C  C   . GLY C 1 278 ? -23.914 28.793  -46.315 1.00 31.61  ? 278 GLY D C   1 
ATOM   6891  O  O   . GLY C 1 278 ? -23.660 28.367  -47.442 1.00 36.66  ? 278 GLY D O   1 
ATOM   6892  N  N   . ARG C 1 279 ? -25.014 29.480  -46.054 1.00 34.75  ? 279 ARG D N   1 
ATOM   6893  C  CA  . ARG C 1 279 ? -25.985 29.791  -47.087 1.00 31.12  ? 279 ARG D CA  1 
ATOM   6894  C  C   . ARG C 1 279 ? -25.605 31.105  -47.785 1.00 33.21  ? 279 ARG D C   1 
ATOM   6895  O  O   . ARG C 1 279 ? -24.649 31.777  -47.401 1.00 30.62  ? 279 ARG D O   1 
ATOM   6896  C  CB  . ARG C 1 279 ? -27.376 29.821  -46.456 1.00 34.27  ? 279 ARG D CB  1 
ATOM   6897  C  CG  . ARG C 1 279 ? -28.087 28.452  -46.532 1.00 42.34  ? 279 ARG D CG  1 
ATOM   6898  C  CD  . ARG C 1 279 ? -29.258 28.318  -45.549 1.00 43.20  ? 279 ARG D CD  1 
ATOM   6899  N  NE  . ARG C 1 279 ? -28.807 28.471  -44.168 1.00 48.41  ? 279 ARG D NE  1 
ATOM   6900  C  CZ  . ARG C 1 279 ? -29.602 28.549  -43.108 1.00 44.50  ? 279 ARG D CZ  1 
ATOM   6901  N  NH1 . ARG C 1 279 ? -30.913 28.476  -43.217 1.00 49.88  ? 279 ARG D NH1 1 
ATOM   6902  N  NH2 . ARG C 1 279 ? -29.067 28.707  -41.904 1.00 48.58  ? 279 ARG D NH2 1 
ATOM   6903  N  N   . THR C 1 280 ? -26.322 31.440  -48.866 1.00 30.97  ? 280 THR D N   1 
ATOM   6904  C  CA  . THR C 1 280 ? -26.108 32.696  -49.581 1.00 28.25  ? 280 THR D CA  1 
ATOM   6905  C  C   . THR C 1 280 ? -27.439 33.407  -49.864 1.00 29.73  ? 280 THR D C   1 
ATOM   6906  O  O   . THR C 1 280 ? -28.529 32.829  -49.774 1.00 26.65  ? 280 THR D O   1 
ATOM   6907  C  CB  . THR C 1 280 ? -25.297 32.481  -50.887 1.00 31.92  ? 280 THR D CB  1 
ATOM   6908  O  OG1 . THR C 1 280 ? -26.078 31.762  -51.855 1.00 34.15  ? 280 THR D OG1 1 
ATOM   6909  C  CG2 . THR C 1 280 ? -23.987 31.715  -50.607 1.00 33.42  ? 280 THR D CG2 1 
ATOM   6910  N  N   . ILE C 1 281 ? -27.332 34.698  -50.154 1.00 23.66  ? 281 ILE D N   1 
ATOM   6911  C  CA  . ILE C 1 281 ? -28.463 35.567  -50.459 1.00 24.91  ? 281 ILE D CA  1 
ATOM   6912  C  C   . ILE C 1 281 ? -28.067 36.378  -51.685 1.00 28.53  ? 281 ILE D C   1 
ATOM   6913  O  O   . ILE C 1 281 ? -27.108 37.158  -51.625 1.00 27.96  ? 281 ILE D O   1 
ATOM   6914  C  CB  . ILE C 1 281 ? -28.797 36.508  -49.284 1.00 23.98  ? 281 ILE D CB  1 
ATOM   6915  C  CG1 . ILE C 1 281 ? -29.121 35.717  -48.006 1.00 26.26  ? 281 ILE D CG1 1 
ATOM   6916  C  CG2 . ILE C 1 281 ? -29.940 37.445  -49.663 1.00 26.17  ? 281 ILE D CG2 1 
ATOM   6917  C  CD1 . ILE C 1 281 ? -29.325 36.591  -46.745 1.00 20.52  ? 281 ILE D CD1 1 
ATOM   6918  N  N   . LEU C 1 282 ? -28.794 36.201  -52.792 1.00 31.35  ? 282 LEU D N   1 
ATOM   6919  C  CA  . LEU C 1 282 ? -28.434 36.840  -54.056 1.00 28.66  ? 282 LEU D CA  1 
ATOM   6920  C  C   . LEU C 1 282 ? -26.978 36.535  -54.412 1.00 30.80  ? 282 LEU D C   1 
ATOM   6921  O  O   . LEU C 1 282 ? -26.203 37.414  -54.812 1.00 30.58  ? 282 LEU D O   1 
ATOM   6922  C  CB  . LEU C 1 282 ? -28.696 38.347  -53.988 1.00 24.71  ? 282 LEU D CB  1 
ATOM   6923  C  CG  . LEU C 1 282 ? -30.194 38.657  -53.830 1.00 23.73  ? 282 LEU D CG  1 
ATOM   6924  C  CD1 . LEU C 1 282 ? -30.404 40.133  -53.534 1.00 17.59  ? 282 LEU D CD1 1 
ATOM   6925  C  CD2 . LEU C 1 282 ? -31.033 38.195  -55.023 1.00 16.40  ? 282 LEU D CD2 1 
ATOM   6926  N  N   . GLY C 1 283 ? -26.597 35.270  -54.236 1.00 31.74  ? 283 GLY D N   1 
ATOM   6927  C  CA  . GLY C 1 283 ? -25.273 34.822  -54.627 1.00 32.14  ? 283 GLY D CA  1 
ATOM   6928  C  C   . GLY C 1 283 ? -24.149 35.381  -53.788 1.00 34.57  ? 283 GLY D C   1 
ATOM   6929  O  O   . GLY C 1 283 ? -23.014 35.480  -54.269 1.00 38.76  ? 283 GLY D O   1 
ATOM   6930  N  N   . SER C 1 284 ? -24.432 35.811  -52.565 1.00 30.53  ? 284 SER D N   1 
ATOM   6931  C  CA  . SER C 1 284 ? -23.405 36.426  -51.736 1.00 30.88  ? 284 SER D CA  1 
ATOM   6932  C  C   . SER C 1 284 ? -23.335 35.723  -50.391 1.00 24.29  ? 284 SER D C   1 
ATOM   6933  O  O   . SER C 1 284 ? -24.364 35.361  -49.827 1.00 26.34  ? 284 SER D O   1 
ATOM   6934  C  CB  . SER C 1 284 ? -23.665 37.925  -51.535 1.00 24.83  ? 284 SER D CB  1 
ATOM   6935  O  OG  . SER C 1 284 ? -22.664 38.467  -50.701 1.00 26.47  ? 284 SER D OG  1 
ATOM   6936  N  N   . ALA C 1 285 ? -22.124 35.541  -49.880 1.00 25.18  ? 285 ALA D N   1 
ATOM   6937  C  CA  . ALA C 1 285 ? -21.917 34.912  -48.579 1.00 34.43  ? 285 ALA D CA  1 
ATOM   6938  C  C   . ALA C 1 285 ? -21.815 35.913  -47.428 1.00 29.72  ? 285 ALA D C   1 
ATOM   6939  O  O   . ALA C 1 285 ? -21.700 35.505  -46.274 1.00 33.83  ? 285 ALA D O   1 
ATOM   6940  C  CB  . ALA C 1 285 ? -20.659 34.032  -48.623 1.00 33.94  ? 285 ALA D CB  1 
ATOM   6941  N  N   . LEU C 1 286 ? -21.861 37.205  -47.698 1.00 33.82  ? 286 LEU D N   1 
ATOM   6942  C  CA  . LEU C 1 286 ? -21.954 38.205  -46.648 1.00 31.10  ? 286 LEU D CA  1 
ATOM   6943  C  C   . LEU C 1 286 ? -23.118 39.135  -46.972 1.00 32.12  ? 286 LEU D C   1 
ATOM   6944  O  O   . LEU C 1 286 ? -23.741 39.035  -48.031 1.00 32.42  ? 286 LEU D O   1 
ATOM   6945  C  CB  . LEU C 1 286 ? -20.642 38.983  -46.489 1.00 27.54  ? 286 LEU D CB  1 
ATOM   6946  C  CG  . LEU C 1 286 ? -19.902 39.428  -47.744 1.00 33.38  ? 286 LEU D CG  1 
ATOM   6947  C  CD1 . LEU C 1 286 ? -20.586 40.600  -48.444 1.00 35.02  ? 286 LEU D CD1 1 
ATOM   6948  C  CD2 . LEU C 1 286 ? -18.473 39.779  -47.393 1.00 33.82  ? 286 LEU D CD2 1 
ATOM   6949  N  N   . LEU C 1 287 ? -23.422 40.025  -46.029 1.00 27.55  ? 287 LEU D N   1 
ATOM   6950  C  CA  . LEU C 1 287 ? -24.527 40.957  -46.150 1.00 27.26  ? 287 LEU D CA  1 
ATOM   6951  C  C   . LEU C 1 287 ? -24.047 42.191  -46.917 1.00 31.30  ? 287 LEU D C   1 
ATOM   6952  O  O   . LEU C 1 287 ? -23.103 42.867  -46.495 1.00 28.40  ? 287 LEU D O   1 
ATOM   6953  C  CB  . LEU C 1 287 ? -25.066 41.316  -44.764 1.00 24.80  ? 287 LEU D CB  1 
ATOM   6954  C  CG  . LEU C 1 287 ? -25.552 40.122  -43.907 1.00 32.01  ? 287 LEU D CG  1 
ATOM   6955  C  CD1 . LEU C 1 287 ? -25.949 40.521  -42.482 1.00 24.41  ? 287 LEU D CD1 1 
ATOM   6956  C  CD2 . LEU C 1 287 ? -26.700 39.294  -44.557 1.00 27.56  ? 287 LEU D CD2 1 
ATOM   6957  N  N   . GLU C 1 288 ? -24.671 42.456  -48.058 1.00 25.45  ? 288 GLU D N   1 
ATOM   6958  C  CA  . GLU C 1 288 ? -24.270 43.546  -48.938 1.00 24.84  ? 288 GLU D CA  1 
ATOM   6959  C  C   . GLU C 1 288 ? -24.834 44.888  -48.477 1.00 26.95  ? 288 GLU D C   1 
ATOM   6960  O  O   . GLU C 1 288 ? -26.053 45.027  -48.306 1.00 26.75  ? 288 GLU D O   1 
ATOM   6961  C  CB  . GLU C 1 288 ? -24.758 43.231  -50.345 1.00 26.95  ? 288 GLU D CB  1 
ATOM   6962  C  CG  . GLU C 1 288 ? -23.887 42.230  -51.027 1.00 28.83  ? 288 GLU D CG  1 
ATOM   6963  C  CD  . GLU C 1 288 ? -22.623 42.882  -51.489 1.00 46.83  ? 288 GLU D CD  1 
ATOM   6964  O  OE1 . GLU C 1 288 ? -22.627 44.135  -51.650 1.00 44.75  ? 288 GLU D OE1 1 
ATOM   6965  O  OE2 . GLU C 1 288 ? -21.620 42.153  -51.640 1.00 58.52  ? 288 GLU D OE2 1 
ATOM   6966  N  N   . ASP C 1 289 ? -23.961 45.905  -48.355 1.00 23.25  ? 289 ASP D N   1 
ATOM   6967  C  CA  . ASP C 1 289 ? -24.390 47.226  -47.901 1.00 21.75  ? 289 ASP D CA  1 
ATOM   6968  C  C   . ASP C 1 289 ? -24.098 48.330  -48.920 1.00 23.88  ? 289 ASP D C   1 
ATOM   6969  O  O   . ASP C 1 289 ? -24.042 49.507  -48.544 1.00 20.84  ? 289 ASP D O   1 
ATOM   6970  C  CB  . ASP C 1 289 ? -23.751 47.579  -46.547 1.00 20.47  ? 289 ASP D CB  1 
ATOM   6971  C  CG  . ASP C 1 289 ? -22.265 48.035  -46.657 1.00 27.26  ? 289 ASP D CG  1 
ATOM   6972  O  OD1 . ASP C 1 289 ? -21.577 47.728  -47.662 1.00 19.71  ? 289 ASP D OD1 1 
ATOM   6973  O  OD2 . ASP C 1 289 ? -21.787 48.712  -45.704 1.00 20.76  ? 289 ASP D OD2 1 
ATOM   6974  N  N   . GLU C 1 290 ? -23.893 47.998  -50.202 1.00 22.09  ? 290 GLU D N   1 
ATOM   6975  C  CA  . GLU C 1 290 ? -23.637 49.037  -51.205 1.00 27.69  ? 290 GLU D CA  1 
ATOM   6976  C  C   . GLU C 1 290 ? -24.741 49.105  -52.258 1.00 28.79  ? 290 GLU D C   1 
ATOM   6977  O  O   . GLU C 1 290 ? -24.493 49.456  -53.415 1.00 27.62  ? 290 GLU D O   1 
ATOM   6978  C  CB  . GLU C 1 290 ? -22.256 48.862  -51.845 1.00 20.23  ? 290 GLU D CB  1 
ATOM   6979  C  CG  . GLU C 1 290 ? -21.148 49.292  -50.889 1.00 25.20  ? 290 GLU D CG  1 
ATOM   6980  C  CD  . GLU C 1 290 ? -19.786 49.495  -51.543 1.00 32.87  ? 290 GLU D CD  1 
ATOM   6981  O  OE1 . GLU C 1 290 ? -19.608 49.059  -52.709 1.00 35.59  ? 290 GLU D OE1 1 
ATOM   6982  O  OE2 . GLU C 1 290 ? -18.907 50.130  -50.898 1.00 27.70  ? 290 GLU D OE2 1 
ATOM   6983  N  N   . PHE C 1 291 ? -25.968 48.773  -51.863 1.00 22.36  ? 291 PHE D N   1 
ATOM   6984  C  CA  . PHE C 1 291 ? -27.160 49.058  -52.646 1.00 22.08  ? 291 PHE D CA  1 
ATOM   6985  C  C   . PHE C 1 291 ? -28.041 49.984  -51.825 1.00 24.23  ? 291 PHE D C   1 
ATOM   6986  O  O   . PHE C 1 291 ? -28.533 49.583  -50.767 1.00 23.84  ? 291 PHE D O   1 
ATOM   6987  C  CB  . PHE C 1 291 ? -27.922 47.775  -52.989 1.00 24.71  ? 291 PHE D CB  1 
ATOM   6988  C  CG  . PHE C 1 291 ? -27.212 46.863  -53.951 1.00 20.68  ? 291 PHE D CG  1 
ATOM   6989  C  CD1 . PHE C 1 291 ? -27.318 47.057  -55.323 1.00 26.36  ? 291 PHE D CD1 1 
ATOM   6990  C  CD2 . PHE C 1 291 ? -26.444 45.806  -53.485 1.00 22.89  ? 291 PHE D CD2 1 
ATOM   6991  C  CE1 . PHE C 1 291 ? -26.669 46.197  -56.218 1.00 25.47  ? 291 PHE D CE1 1 
ATOM   6992  C  CE2 . PHE C 1 291 ? -25.795 44.939  -54.371 1.00 23.89  ? 291 PHE D CE2 1 
ATOM   6993  C  CZ  . PHE C 1 291 ? -25.905 45.141  -55.732 1.00 24.36  ? 291 PHE D CZ  1 
ATOM   6994  N  N   . THR C 1 292 ? -28.241 51.212  -52.305 1.00 21.17  ? 292 THR D N   1 
ATOM   6995  C  CA  . THR C 1 292 ? -29.161 52.115  -51.648 1.00 25.33  ? 292 THR D CA  1 
ATOM   6996  C  C   . THR C 1 292 ? -30.576 51.602  -51.864 1.00 20.52  ? 292 THR D C   1 
ATOM   6997  O  O   . THR C 1 292 ? -30.810 50.751  -52.719 1.00 21.80  ? 292 THR D O   1 
ATOM   6998  C  CB  . THR C 1 292 ? -29.049 53.547  -52.200 1.00 25.80  ? 292 THR D CB  1 
ATOM   6999  O  OG1 . THR C 1 292 ? -29.619 53.593  -53.517 1.00 29.92  ? 292 THR D OG1 1 
ATOM   7000  C  CG2 . THR C 1 292 ? -27.616 54.023  -52.249 1.00 23.56  ? 292 THR D CG2 1 
ATOM   7001  N  N   . PRO C 1 293 ? -31.544 52.110  -51.096 1.00 20.87  ? 293 PRO D N   1 
ATOM   7002  C  CA  . PRO C 1 293 ? -32.946 51.777  -51.377 1.00 20.24  ? 293 PRO D CA  1 
ATOM   7003  C  C   . PRO C 1 293 ? -33.379 52.197  -52.762 1.00 26.17  ? 293 PRO D C   1 
ATOM   7004  O  O   . PRO C 1 293 ? -34.177 51.484  -53.396 1.00 26.76  ? 293 PRO D O   1 
ATOM   7005  C  CB  . PRO C 1 293 ? -33.708 52.551  -50.291 1.00 26.00  ? 293 PRO D CB  1 
ATOM   7006  C  CG  . PRO C 1 293 ? -32.747 52.671  -49.190 1.00 22.58  ? 293 PRO D CG  1 
ATOM   7007  C  CD  . PRO C 1 293 ? -31.406 52.857  -49.838 1.00 20.35  ? 293 PRO D CD  1 
ATOM   7008  N  N   . PHE C 1 294 ? -32.839 53.323  -53.261 1.00 28.05  ? 294 PHE D N   1 
ATOM   7009  C  CA  . PHE C 1 294 ? -33.110 53.754  -54.627 1.00 25.78  ? 294 PHE D CA  1 
ATOM   7010  C  C   . PHE C 1 294 ? -32.507 52.789  -55.642 1.00 26.61  ? 294 PHE D C   1 
ATOM   7011  O  O   . PHE C 1 294 ? -33.159 52.460  -56.637 1.00 28.77  ? 294 PHE D O   1 
ATOM   7012  C  CB  . PHE C 1 294 ? -32.562 55.162  -54.846 1.00 30.65  ? 294 PHE D CB  1 
ATOM   7013  C  CG  . PHE C 1 294 ? -32.620 55.633  -56.286 1.00 38.15  ? 294 PHE D CG  1 
ATOM   7014  C  CD1 . PHE C 1 294 ? -31.640 55.258  -57.204 1.00 39.09  ? 294 PHE D CD1 1 
ATOM   7015  C  CD2 . PHE C 1 294 ? -33.624 56.501  -56.706 1.00 42.44  ? 294 PHE D CD2 1 
ATOM   7016  C  CE1 . PHE C 1 294 ? -31.697 55.696  -58.521 1.00 47.09  ? 294 PHE D CE1 1 
ATOM   7017  C  CE2 . PHE C 1 294 ? -33.678 56.955  -58.023 1.00 37.31  ? 294 PHE D CE2 1 
ATOM   7018  C  CZ  . PHE C 1 294 ? -32.721 56.552  -58.925 1.00 42.10  ? 294 PHE D CZ  1 
ATOM   7019  N  N   . ASP C 1 295 ? -31.271 52.323  -55.410 1.00 24.61  ? 295 ASP D N   1 
ATOM   7020  C  CA  . ASP C 1 295 ? -30.659 51.353  -56.323 1.00 24.32  ? 295 ASP D CA  1 
ATOM   7021  C  C   . ASP C 1 295 ? -31.570 50.165  -56.529 1.00 24.81  ? 295 ASP D C   1 
ATOM   7022  O  O   . ASP C 1 295 ? -31.785 49.722  -57.662 1.00 26.79  ? 295 ASP D O   1 
ATOM   7023  C  CB  . ASP C 1 295 ? -29.313 50.852  -55.790 1.00 25.90  ? 295 ASP D CB  1 
ATOM   7024  C  CG  . ASP C 1 295 ? -28.274 51.938  -55.711 1.00 29.79  ? 295 ASP D CG  1 
ATOM   7025  O  OD1 . ASP C 1 295 ? -28.531 53.006  -56.299 1.00 32.56  ? 295 ASP D OD1 1 
ATOM   7026  O  OD2 . ASP C 1 295 ? -27.218 51.740  -55.061 1.00 23.32  ? 295 ASP D OD2 1 
ATOM   7027  N  N   . VAL C 1 296 ? -32.115 49.632  -55.428 1.00 27.56  ? 296 VAL D N   1 
ATOM   7028  C  CA  . VAL C 1 296 ? -32.966 48.448  -55.510 1.00 26.79  ? 296 VAL D CA  1 
ATOM   7029  C  C   . VAL C 1 296 ? -34.189 48.738  -56.365 1.00 25.43  ? 296 VAL D C   1 
ATOM   7030  O  O   . VAL C 1 296 ? -34.456 48.038  -57.348 1.00 32.21  ? 296 VAL D O   1 
ATOM   7031  C  CB  . VAL C 1 296 ? -33.374 47.969  -54.102 1.00 26.73  ? 296 VAL D CB  1 
ATOM   7032  C  CG1 . VAL C 1 296 ? -34.355 46.792  -54.214 1.00 24.24  ? 296 VAL D CG1 1 
ATOM   7033  C  CG2 . VAL C 1 296 ? -32.158 47.604  -53.286 1.00 21.74  ? 296 VAL D CG2 1 
ATOM   7034  N  N   . VAL C 1 297 ? -34.946 49.779  -56.000 1.00 23.25  ? 297 VAL D N   1 
ATOM   7035  C  CA  . VAL C 1 297 ? -36.143 50.145  -56.759 1.00 29.02  ? 297 VAL D CA  1 
ATOM   7036  C  C   . VAL C 1 297 ? -35.797 50.376  -58.227 1.00 32.69  ? 297 VAL D C   1 
ATOM   7037  O  O   . VAL C 1 297 ? -36.501 49.909  -59.130 1.00 35.16  ? 297 VAL D O   1 
ATOM   7038  C  CB  . VAL C 1 297 ? -36.825 51.380  -56.140 1.00 30.43  ? 297 VAL D CB  1 
ATOM   7039  C  CG1 . VAL C 1 297 ? -37.901 51.890  -57.056 1.00 26.47  ? 297 VAL D CG1 1 
ATOM   7040  C  CG2 . VAL C 1 297 ? -37.424 51.039  -54.802 1.00 25.18  ? 297 VAL D CG2 1 
ATOM   7041  N  N   . ARG C 1 298 ? -34.718 51.119  -58.485 1.00 29.28  ? 298 ARG D N   1 
ATOM   7042  C  CA  . ARG C 1 298 ? -34.303 51.387  -59.859 1.00 32.46  ? 298 ARG D CA  1 
ATOM   7043  C  C   . ARG C 1 298 ? -34.104 50.089  -60.629 1.00 40.67  ? 298 ARG D C   1 
ATOM   7044  O  O   . ARG C 1 298 ? -34.678 49.890  -61.706 1.00 42.39  ? 298 ARG D O   1 
ATOM   7045  C  CB  . ARG C 1 298 ? -33.008 52.210  -59.844 1.00 37.97  ? 298 ARG D CB  1 
ATOM   7046  C  CG  . ARG C 1 298 ? -32.316 52.416  -61.186 1.00 48.07  ? 298 ARG D CG  1 
ATOM   7047  C  CD  . ARG C 1 298 ? -31.081 53.346  -61.058 1.00 51.90  ? 298 ARG D CD  1 
ATOM   7048  N  NE  . ARG C 1 298 ? -29.928 52.772  -60.355 1.00 53.95  ? 298 ARG D NE  1 
ATOM   7049  C  CZ  . ARG C 1 298 ? -28.886 52.184  -60.944 1.00 51.64  ? 298 ARG D CZ  1 
ATOM   7050  N  NH1 . ARG C 1 298 ? -28.811 52.055  -62.261 1.00 51.13  ? 298 ARG D NH1 1 
ATOM   7051  N  NH2 . ARG C 1 298 ? -27.878 51.741  -60.197 1.00 40.12  ? 298 ARG D NH2 1 
ATOM   7052  N  N   . GLN C 1 299 ? -33.311 49.178  -60.070 1.00 36.42  ? 299 GLN D N   1 
ATOM   7053  C  CA  . GLN C 1 299 ? -33.010 47.953  -60.786 1.00 32.31  ? 299 GLN D CA  1 
ATOM   7054  C  C   . GLN C 1 299 ? -34.231 47.054  -60.860 1.00 38.12  ? 299 GLN D C   1 
ATOM   7055  O  O   . GLN C 1 299 ? -34.436 46.367  -61.865 1.00 42.68  ? 299 GLN D O   1 
ATOM   7056  C  CB  . GLN C 1 299 ? -31.840 47.225  -60.129 1.00 28.55  ? 299 GLN D CB  1 
ATOM   7057  C  CG  . GLN C 1 299 ? -31.424 46.010  -60.918 1.00 32.10  ? 299 GLN D CG  1 
ATOM   7058  C  CD  . GLN C 1 299 ? -30.203 45.294  -60.374 1.00 28.04  ? 299 GLN D CD  1 
ATOM   7059  O  OE1 . GLN C 1 299 ? -29.989 44.146  -60.698 1.00 26.46  ? 299 GLN D OE1 1 
ATOM   7060  N  NE2 . GLN C 1 299 ? -29.395 45.977  -59.560 1.00 26.59  ? 299 GLN D NE2 1 
ATOM   7061  N  N   . CYS C 1 300 ? -35.055 47.040  -59.814 1.00 36.14  ? 300 CYS D N   1 
ATOM   7062  C  CA  . CYS C 1 300 ? -36.194 46.129  -59.807 1.00 39.23  ? 300 CYS D CA  1 
ATOM   7063  C  C   . CYS C 1 300 ? -37.406 46.667  -60.560 1.00 38.52  ? 300 CYS D C   1 
ATOM   7064  O  O   . CYS C 1 300 ? -38.377 45.927  -60.720 1.00 47.86  ? 300 CYS D O   1 
ATOM   7065  C  CB  . CYS C 1 300 ? -36.583 45.775  -58.370 1.00 35.93  ? 300 CYS D CB  1 
ATOM   7066  S  SG  . CYS C 1 300 ? -35.351 44.733  -57.527 1.00 42.58  ? 300 CYS D SG  1 
ATOM   7067  N  N   . SER C 1 301 ? -37.399 47.930  -60.995 1.00 40.08  ? 301 SER D N   1 
ATOM   7068  C  CA  . SER C 1 301 ? -38.520 48.492  -61.739 1.00 41.35  ? 301 SER D CA  1 
ATOM   7069  C  C   . SER C 1 301 ? -38.218 48.800  -63.202 1.00 48.45  ? 301 SER D C   1 
ATOM   7070  O  O   . SER C 1 301 ? -39.160 48.980  -63.982 1.00 54.50  ? 301 SER D O   1 
ATOM   7071  C  CB  . SER C 1 301 ? -39.025 49.775  -61.059 1.00 51.17  ? 301 SER D CB  1 
ATOM   7072  O  OG  . SER C 1 301 ? -38.302 50.913  -61.500 1.00 51.07  ? 301 SER D OG  1 
ATOM   7073  N  N   . GLY C 1 302 ? -36.948 48.895  -63.591 1.00 51.87  ? 302 GLY D N   1 
ATOM   7074  C  CA  . GLY C 1 302 ? -36.594 49.064  -64.990 1.00 52.53  ? 302 GLY D CA  1 
ATOM   7075  C  C   . GLY C 1 302 ? -36.395 50.491  -65.455 1.00 60.77  ? 302 GLY D C   1 
ATOM   7076  O  O   . GLY C 1 302 ? -36.620 50.781  -66.637 1.00 54.77  ? 302 GLY D O   1 
ATOM   7077  N  N   . VAL C 1 303 ? -35.959 51.390  -64.569 1.00 57.36  ? 303 VAL D N   1 
ATOM   7078  C  CA  . VAL C 1 303 ? -35.787 52.792  -64.929 1.00 68.48  ? 303 VAL D CA  1 
ATOM   7079  C  C   . VAL C 1 303 ? -34.671 52.932  -65.957 1.00 78.70  ? 303 VAL D C   1 
ATOM   7080  O  O   . VAL C 1 303 ? -33.593 52.336  -65.822 1.00 75.42  ? 303 VAL D O   1 
ATOM   7081  C  CB  . VAL C 1 303 ? -35.502 53.629  -63.668 1.00 66.01  ? 303 VAL D CB  1 
ATOM   7082  C  CG1 . VAL C 1 303 ? -34.933 54.999  -64.032 1.00 75.73  ? 303 VAL D CG1 1 
ATOM   7083  C  CG2 . VAL C 1 303 ? -36.775 53.793  -62.848 1.00 58.79  ? 303 VAL D CG2 1 
ATOM   7084  N  N   . THR C 1 304 ? -34.925 53.733  -66.990 1.00 85.17  ? 304 THR D N   1 
ATOM   7085  C  CA  . THR C 1 304 ? -33.992 53.941  -68.086 1.00 75.13  ? 304 THR D CA  1 
ATOM   7086  C  C   . THR C 1 304 ? -33.560 55.399  -68.135 1.00 85.87  ? 304 THR D C   1 
ATOM   7087  O  O   . THR C 1 304 ? -34.084 56.257  -67.417 1.00 81.30  ? 304 THR D O   1 
ATOM   7088  C  CB  . THR C 1 304 ? -34.609 53.532  -69.430 1.00 73.48  ? 304 THR D CB  1 
ATOM   7089  O  OG1 . THR C 1 304 ? -35.793 54.305  -69.676 1.00 80.49  ? 304 THR D OG1 1 
ATOM   7090  C  CG2 . THR C 1 304 ? -34.960 52.062  -69.424 1.00 74.74  ? 304 THR D CG2 1 
ATOM   7091  N  N   . PHE C 1 305 ? -32.598 55.664  -69.016 1.00 90.44  ? 305 PHE D N   1 
ATOM   7092  C  CA  . PHE C 1 305 ? -32.028 56.996  -69.176 1.00 91.71  ? 305 PHE D CA  1 
ATOM   7093  C  C   . PHE C 1 305 ? -31.835 57.329  -70.653 1.00 91.40  ? 305 PHE D C   1 
ATOM   7094  O  O   . PHE C 1 305 ? -32.623 58.072  -71.241 1.00 90.82  ? 305 PHE D O   1 
ATOM   7095  C  CB  . PHE C 1 305 ? -30.693 57.102  -68.426 1.00 87.50  ? 305 PHE D CB  1 
ATOM   7096  C  CG  . PHE C 1 305 ? -30.743 56.560  -67.025 1.00 86.53  ? 305 PHE D CG  1 
ATOM   7097  C  CD1 . PHE C 1 305 ? -31.347 57.287  -66.008 1.00 85.84  ? 305 PHE D CD1 1 
ATOM   7098  C  CD2 . PHE C 1 305 ? -30.182 55.329  -66.724 1.00 89.30  ? 305 PHE D CD2 1 
ATOM   7099  C  CE1 . PHE C 1 305 ? -31.403 56.792  -64.720 1.00 87.62  ? 305 PHE D CE1 1 
ATOM   7100  C  CE2 . PHE C 1 305 ? -30.230 54.826  -65.435 1.00 88.95  ? 305 PHE D CE2 1 
ATOM   7101  C  CZ  . PHE C 1 305 ? -30.843 55.560  -64.431 1.00 91.42  ? 305 PHE D CZ  1 
ATOM   7102  N  N   . SER D 1 1   ? -4.488  49.540  -54.611 1.00 42.07  ? 1   SER C N   1 
ATOM   7103  C  CA  . SER D 1 1   ? -5.021  49.827  -55.966 1.00 37.74  ? 1   SER C CA  1 
ATOM   7104  C  C   . SER D 1 1   ? -6.441  49.267  -56.127 1.00 33.32  ? 1   SER C C   1 
ATOM   7105  O  O   . SER D 1 1   ? -7.234  49.929  -56.755 1.00 28.44  ? 1   SER C O   1 
ATOM   7106  C  CB  . SER D 1 1   ? -4.062  49.356  -56.989 1.00 41.88  ? 1   SER C CB  1 
ATOM   7107  O  OG  . SER D 1 1   ? -3.018  50.306  -57.145 1.00 45.60  ? 1   SER C OG  1 
ATOM   7108  N  N   . GLY D 1 2   ? -6.742  48.100  -55.559 1.00 34.23  ? 2   GLY C N   1 
ATOM   7109  C  CA  . GLY D 1 2   ? -8.124  47.581  -55.545 1.00 29.72  ? 2   GLY C CA  1 
ATOM   7110  C  C   . GLY D 1 2   ? -8.524  46.623  -56.650 1.00 29.50  ? 2   GLY C C   1 
ATOM   7111  O  O   . GLY D 1 2   ? -7.859  46.608  -57.694 1.00 34.34  ? 2   GLY C O   1 
ATOM   7112  N  N   . PHE D 1 3   ? -9.599  45.866  -56.414 1.00 27.78  ? 3   PHE C N   1 
ATOM   7113  C  CA  . PHE D 1 3   ? -10.126 44.895  -57.408 1.00 24.20  ? 3   PHE C CA  1 
ATOM   7114  C  C   . PHE D 1 3   ? -11.653 44.842  -57.336 1.00 26.58  ? 3   PHE C C   1 
ATOM   7115  O  O   . PHE D 1 3   ? -12.209 44.378  -56.338 1.00 30.74  ? 3   PHE C O   1 
ATOM   7116  C  CB  . PHE D 1 3   ? -9.511  43.514  -57.236 1.00 24.29  ? 3   PHE C CB  1 
ATOM   7117  C  CG  . PHE D 1 3   ? -9.505  42.689  -58.495 1.00 27.26  ? 3   PHE C CG  1 
ATOM   7118  C  CD1 . PHE D 1 3   ? -8.628  42.977  -59.525 1.00 21.92  ? 3   PHE C CD1 1 
ATOM   7119  C  CD2 . PHE D 1 3   ? -10.379 41.627  -58.652 1.00 26.79  ? 3   PHE C CD2 1 
ATOM   7120  C  CE1 . PHE D 1 3   ? -8.622  42.218  -60.682 1.00 26.98  ? 3   PHE C CE1 1 
ATOM   7121  C  CE2 . PHE D 1 3   ? -10.367 40.868  -59.809 1.00 24.57  ? 3   PHE C CE2 1 
ATOM   7122  C  CZ  . PHE D 1 3   ? -9.495  41.168  -60.825 1.00 28.02  ? 3   PHE C CZ  1 
ATOM   7123  N  N   . ARG D 1 4   ? -12.295 45.257  -58.412 1.00 22.96  ? 4   ARG C N   1 
ATOM   7124  C  CA  . ARG D 1 4   ? -13.735 45.302  -58.499 1.00 26.38  ? 4   ARG C CA  1 
ATOM   7125  C  C   . ARG D 1 4   ? -14.190 44.464  -59.682 1.00 25.13  ? 4   ARG C C   1 
ATOM   7126  O  O   . ARG D 1 4   ? -13.432 44.215  -60.627 1.00 22.86  ? 4   ARG C O   1 
ATOM   7127  C  CB  . ARG D 1 4   ? -14.234 46.749  -58.655 1.00 29.12  ? 4   ARG C CB  1 
ATOM   7128  C  CG  . ARG D 1 4   ? -14.426 47.502  -57.349 1.00 31.22  ? 4   ARG C CG  1 
ATOM   7129  C  CD  . ARG D 1 4   ? -15.853 47.339  -56.832 1.00 30.65  ? 4   ARG C CD  1 
ATOM   7130  N  NE  . ARG D 1 4   ? -16.114 48.276  -55.747 1.00 36.18  ? 4   ARG C NE  1 
ATOM   7131  C  CZ  . ARG D 1 4   ? -17.140 48.198  -54.905 1.00 44.42  ? 4   ARG C CZ  1 
ATOM   7132  N  NH1 . ARG D 1 4   ? -18.065 47.255  -55.019 1.00 41.12  ? 4   ARG C NH1 1 
ATOM   7133  N  NH2 . ARG D 1 4   ? -17.226 49.072  -53.903 1.00 32.93  ? 4   ARG C NH2 1 
ATOM   7134  N  N   . LYS D 1 5   ? -15.433 43.997  -59.586 1.00 24.73  ? 5   LYS C N   1 
ATOM   7135  C  CA  . LYS D 1 5   ? -16.133 43.452  -60.742 1.00 32.95  ? 5   LYS C CA  1 
ATOM   7136  C  C   . LYS D 1 5   ? -16.401 44.617  -61.696 1.00 29.20  ? 5   LYS C C   1 
ATOM   7137  O  O   . LYS D 1 5   ? -17.187 45.520  -61.387 1.00 32.48  ? 5   LYS C O   1 
ATOM   7138  C  CB  . LYS D 1 5   ? -17.417 42.751  -60.303 1.00 23.97  ? 5   LYS C CB  1 
ATOM   7139  C  CG  . LYS D 1 5   ? -18.149 41.965  -61.382 1.00 34.83  ? 5   LYS C CG  1 
ATOM   7140  C  CD  . LYS D 1 5   ? -17.335 40.802  -61.961 1.00 33.48  ? 5   LYS C CD  1 
ATOM   7141  C  CE  . LYS D 1 5   ? -17.272 39.625  -60.981 1.00 31.87  ? 5   LYS C CE  1 
ATOM   7142  N  NZ  . LYS D 1 5   ? -18.588 39.001  -60.748 1.00 43.89  ? 5   LYS C NZ  1 
ATOM   7143  N  N   . MET D 1 6   ? -15.688 44.630  -62.815 1.00 26.96  ? 6   MET C N   1 
ATOM   7144  C  CA  . MET D 1 6   ? -15.571 45.786  -63.690 1.00 29.46  ? 6   MET C CA  1 
ATOM   7145  C  C   . MET D 1 6   ? -16.151 45.479  -65.063 1.00 27.90  ? 6   MET C C   1 
ATOM   7146  O  O   . MET D 1 6   ? -15.780 44.477  -65.676 1.00 31.98  ? 6   MET C O   1 
ATOM   7147  C  CB  . MET D 1 6   ? -14.111 46.191  -63.828 1.00 26.65  ? 6   MET C CB  1 
ATOM   7148  C  CG  . MET D 1 6   ? -13.933 47.582  -64.341 1.00 31.64  ? 6   MET C CG  1 
ATOM   7149  S  SD  . MET D 1 6   ? -12.187 47.904  -64.551 1.00 39.02  ? 6   MET C SD  1 
ATOM   7150  C  CE  . MET D 1 6   ? -11.819 48.943  -63.144 1.00 30.43  ? 6   MET C CE  1 
ATOM   7151  N  N   . ALA D 1 7   ? -17.023 46.353  -65.556 1.00 22.78  ? 7   ALA C N   1 
ATOM   7152  C  CA  . ALA D 1 7   ? -17.600 46.220  -66.883 1.00 22.34  ? 7   ALA C CA  1 
ATOM   7153  C  C   . ALA D 1 7   ? -16.845 47.065  -67.899 1.00 23.42  ? 7   ALA C C   1 
ATOM   7154  O  O   . ALA D 1 7   ? -16.243 48.085  -67.557 1.00 23.83  ? 7   ALA C O   1 
ATOM   7155  C  CB  . ALA D 1 7   ? -19.071 46.636  -66.868 1.00 23.06  ? 7   ALA C CB  1 
ATOM   7156  N  N   . PHE D 1 8   ? -16.885 46.639  -69.163 1.00 24.23  ? 8   PHE C N   1 
ATOM   7157  C  CA  . PHE D 1 8   ? -16.383 47.495  -70.228 1.00 26.41  ? 8   PHE C CA  1 
ATOM   7158  C  C   . PHE D 1 8   ? -17.197 48.788  -70.292 1.00 27.16  ? 8   PHE C C   1 
ATOM   7159  O  O   . PHE D 1 8   ? -18.400 48.795  -69.998 1.00 24.98  ? 8   PHE C O   1 
ATOM   7160  C  CB  . PHE D 1 8   ? -16.446 46.786  -71.583 1.00 28.63  ? 8   PHE C CB  1 
ATOM   7161  C  CG  . PHE D 1 8   ? -15.387 45.739  -71.773 1.00 28.69  ? 8   PHE C CG  1 
ATOM   7162  C  CD1 . PHE D 1 8   ? -14.089 46.098  -72.093 1.00 31.31  ? 8   PHE C CD1 1 
ATOM   7163  C  CD2 . PHE D 1 8   ? -15.685 44.398  -71.614 1.00 31.64  ? 8   PHE C CD2 1 
ATOM   7164  C  CE1 . PHE D 1 8   ? -13.113 45.130  -72.262 1.00 32.93  ? 8   PHE C CE1 1 
ATOM   7165  C  CE2 . PHE D 1 8   ? -14.710 43.429  -71.769 1.00 31.55  ? 8   PHE C CE2 1 
ATOM   7166  C  CZ  . PHE D 1 8   ? -13.423 43.798  -72.104 1.00 35.88  ? 8   PHE C CZ  1 
ATOM   7167  N  N   . PRO D 1 9   ? -16.563 49.905  -70.649 1.00 27.48  ? 9   PRO C N   1 
ATOM   7168  C  CA  . PRO D 1 9   ? -17.338 51.122  -70.928 1.00 25.82  ? 9   PRO C CA  1 
ATOM   7169  C  C   . PRO D 1 9   ? -18.307 50.847  -72.066 1.00 26.01  ? 9   PRO C C   1 
ATOM   7170  O  O   . PRO D 1 9   ? -17.962 50.193  -73.057 1.00 28.24  ? 9   PRO C O   1 
ATOM   7171  C  CB  . PRO D 1 9   ? -16.271 52.158  -71.307 1.00 27.56  ? 9   PRO C CB  1 
ATOM   7172  C  CG  . PRO D 1 9   ? -15.083 51.376  -71.722 1.00 31.90  ? 9   PRO C CG  1 
ATOM   7173  C  CD  . PRO D 1 9   ? -15.126 50.076  -70.931 1.00 32.66  ? 9   PRO C CD  1 
ATOM   7174  N  N   . SER D 1 10  ? -19.536 51.329  -71.910 1.00 20.98  ? 10  SER C N   1 
ATOM   7175  C  CA  . SER D 1 10  ? -20.622 50.885  -72.767 1.00 20.80  ? 10  SER C CA  1 
ATOM   7176  C  C   . SER D 1 10  ? -20.983 51.876  -73.860 1.00 22.56  ? 10  SER C C   1 
ATOM   7177  O  O   . SER D 1 10  ? -21.915 51.605  -74.621 1.00 23.24  ? 10  SER C O   1 
ATOM   7178  C  CB  . SER D 1 10  ? -21.860 50.539  -71.920 1.00 21.80  ? 10  SER C CB  1 
ATOM   7179  O  OG  . SER D 1 10  ? -22.372 51.660  -71.207 1.00 26.10  ? 10  SER C OG  1 
ATOM   7180  N  N   . GLY D 1 11  ? -20.236 52.981  -73.997 1.00 24.18  ? 11  GLY C N   1 
ATOM   7181  C  CA  . GLY D 1 11  ? -20.619 54.028  -74.937 1.00 20.58  ? 11  GLY C CA  1 
ATOM   7182  C  C   . GLY D 1 11  ? -20.771 53.549  -76.370 1.00 21.31  ? 11  GLY C C   1 
ATOM   7183  O  O   . GLY D 1 11  ? -21.774 53.842  -77.028 1.00 20.26  ? 11  GLY C O   1 
ATOM   7184  N  N   . LYS D 1 12  ? -19.765 52.830  -76.886 1.00 23.61  ? 12  LYS C N   1 
ATOM   7185  C  CA  . LYS D 1 12  ? -19.836 52.353  -78.270 1.00 25.62  ? 12  LYS C CA  1 
ATOM   7186  C  C   . LYS D 1 12  ? -21.097 51.539  -78.517 1.00 24.22  ? 12  LYS C C   1 
ATOM   7187  O  O   . LYS D 1 12  ? -21.622 51.526  -79.633 1.00 29.02  ? 12  LYS C O   1 
ATOM   7188  C  CB  . LYS D 1 12  ? -18.621 51.489  -78.617 1.00 27.92  ? 12  LYS C CB  1 
ATOM   7189  C  CG  . LYS D 1 12  ? -17.287 52.196  -78.624 1.00 21.17  ? 12  LYS C CG  1 
ATOM   7190  C  CD  . LYS D 1 12  ? -16.233 51.243  -79.103 1.00 17.86  ? 12  LYS C CD  1 
ATOM   7191  C  CE  . LYS D 1 12  ? -14.866 51.837  -78.964 1.00 24.97  ? 12  LYS C CE  1 
ATOM   7192  N  NZ  . LYS D 1 12  ? -14.778 53.017  -79.844 1.00 24.83  ? 12  LYS C NZ  1 
ATOM   7193  N  N   . VAL D 1 13  ? -21.584 50.848  -77.492 1.00 23.63  ? 13  VAL C N   1 
ATOM   7194  C  CA  . VAL D 1 13  ? -22.760 50.009  -77.633 1.00 21.98  ? 13  VAL C CA  1 
ATOM   7195  C  C   . VAL D 1 13  ? -24.045 50.808  -77.432 1.00 18.51  ? 13  VAL C C   1 
ATOM   7196  O  O   . VAL D 1 13  ? -25.057 50.505  -78.059 1.00 21.98  ? 13  VAL C O   1 
ATOM   7197  C  CB  . VAL D 1 13  ? -22.659 48.839  -76.629 1.00 19.82  ? 13  VAL C CB  1 
ATOM   7198  C  CG1 . VAL D 1 13  ? -23.812 47.881  -76.765 1.00 22.20  ? 13  VAL C CG1 1 
ATOM   7199  C  CG2 . VAL D 1 13  ? -21.326 48.117  -76.783 1.00 22.90  ? 13  VAL C CG2 1 
ATOM   7200  N  N   . GLU D 1 14  ? -24.035 51.808  -76.545 1.00 18.50  ? 14  GLU C N   1 
ATOM   7201  C  CA  . GLU D 1 14  ? -25.226 52.622  -76.303 1.00 18.89  ? 14  GLU C CA  1 
ATOM   7202  C  C   . GLU D 1 14  ? -25.737 53.265  -77.583 1.00 23.71  ? 14  GLU C C   1 
ATOM   7203  O  O   . GLU D 1 14  ? -26.948 53.281  -77.837 1.00 24.13  ? 14  GLU C O   1 
ATOM   7204  C  CB  . GLU D 1 14  ? -24.928 53.698  -75.265 1.00 22.72  ? 14  GLU C CB  1 
ATOM   7205  C  CG  . GLU D 1 14  ? -24.607 53.139  -73.902 1.00 22.74  ? 14  GLU C CG  1 
ATOM   7206  C  CD  . GLU D 1 14  ? -24.125 54.212  -72.965 1.00 23.19  ? 14  GLU C CD  1 
ATOM   7207  O  OE1 . GLU D 1 14  ? -24.777 55.276  -72.923 1.00 32.31  ? 14  GLU C OE1 1 
ATOM   7208  O  OE2 . GLU D 1 14  ? -23.122 53.996  -72.254 1.00 23.57  ? 14  GLU C OE2 1 
ATOM   7209  N  N   . GLY D 1 15  ? -24.827 53.792  -78.411 1.00 22.01  ? 15  GLY C N   1 
ATOM   7210  C  CA  . GLY D 1 15  ? -25.214 54.386  -79.666 1.00 23.26  ? 15  GLY C CA  1 
ATOM   7211  C  C   . GLY D 1 15  ? -25.817 53.412  -80.661 1.00 24.50  ? 15  GLY C C   1 
ATOM   7212  O  O   . GLY D 1 15  ? -26.262 53.850  -81.732 1.00 21.96  ? 15  GLY C O   1 
ATOM   7213  N  N   . CYS D 1 16  ? -25.860 52.113  -80.319 1.00 18.31  ? 16  CYS C N   1 
ATOM   7214  C  CA  . CYS D 1 16  ? -26.444 51.078  -81.166 1.00 22.20  ? 16  CYS C CA  1 
ATOM   7215  C  C   . CYS D 1 16  ? -27.806 50.580  -80.695 1.00 21.18  ? 16  CYS C C   1 
ATOM   7216  O  O   . CYS D 1 16  ? -28.398 49.722  -81.358 1.00 20.48  ? 16  CYS C O   1 
ATOM   7217  C  CB  . CYS D 1 16  ? -25.506 49.871  -81.254 1.00 23.65  ? 16  CYS C CB  1 
ATOM   7218  S  SG  . CYS D 1 16  ? -23.891 50.224  -81.912 1.00 25.29  ? 16  CYS C SG  1 
ATOM   7219  N  N   . MET D 1 17  ? -28.302 51.039  -79.559 1.00 21.28  ? 17  MET C N   1 
ATOM   7220  C  CA  . MET D 1 17  ? -29.530 50.474  -79.021 1.00 23.96  ? 17  MET C CA  1 
ATOM   7221  C  C   . MET D 1 17  ? -30.737 51.218  -79.584 1.00 27.13  ? 17  MET C C   1 
ATOM   7222  O  O   . MET D 1 17  ? -30.791 52.451  -79.549 1.00 19.91  ? 17  MET C O   1 
ATOM   7223  C  CB  . MET D 1 17  ? -29.515 50.505  -77.490 1.00 19.22  ? 17  MET C CB  1 
ATOM   7224  C  CG  . MET D 1 17  ? -28.361 49.679  -76.896 1.00 21.24  ? 17  MET C CG  1 
ATOM   7225  S  SD  . MET D 1 17  ? -28.263 47.986  -77.565 1.00 25.57  ? 17  MET C SD  1 
ATOM   7226  C  CE  . MET D 1 17  ? -29.895 47.374  -77.151 1.00 27.63  ? 17  MET C CE  1 
ATOM   7227  N  N   . VAL D 1 18  ? -31.716 50.454  -80.078 1.00 24.17  ? 18  VAL C N   1 
ATOM   7228  C  CA  . VAL D 1 18  ? -32.961 50.994  -80.601 1.00 20.26  ? 18  VAL C CA  1 
ATOM   7229  C  C   . VAL D 1 18  ? -34.114 50.236  -79.962 1.00 21.86  ? 18  VAL C C   1 
ATOM   7230  O  O   . VAL D 1 18  ? -33.925 49.258  -79.237 1.00 19.24  ? 18  VAL C O   1 
ATOM   7231  C  CB  . VAL D 1 18  ? -33.049 50.905  -82.136 1.00 18.08  ? 18  VAL C CB  1 
ATOM   7232  C  CG1 . VAL D 1 18  ? -31.934 51.701  -82.787 1.00 20.18  ? 18  VAL C CG1 1 
ATOM   7233  C  CG2 . VAL D 1 18  ? -32.997 49.452  -82.594 1.00 22.24  ? 18  VAL C CG2 1 
ATOM   7234  N  N   . GLN D 1 19  ? -35.318 50.710  -80.248 1.00 22.81  ? 19  GLN C N   1 
ATOM   7235  C  CA  . GLN D 1 19  ? -36.565 50.146  -79.752 1.00 24.44  ? 19  GLN C CA  1 
ATOM   7236  C  C   . GLN D 1 19  ? -37.338 49.562  -80.923 1.00 22.82  ? 19  GLN C C   1 
ATOM   7237  O  O   . GLN D 1 19  ? -37.634 50.284  -81.883 1.00 24.21  ? 19  GLN C O   1 
ATOM   7238  C  CB  . GLN D 1 19  ? -37.389 51.236  -79.077 1.00 27.96  ? 19  GLN C CB  1 
ATOM   7239  C  CG  . GLN D 1 19  ? -38.823 50.864  -78.823 1.00 30.20  ? 19  GLN C CG  1 
ATOM   7240  C  CD  . GLN D 1 19  ? -39.492 51.854  -77.919 1.00 33.79  ? 19  GLN C CD  1 
ATOM   7241  O  OE1 . GLN D 1 19  ? -38.864 52.809  -77.458 1.00 35.22  ? 19  GLN C OE1 1 
ATOM   7242  N  NE2 . GLN D 1 19  ? -40.770 51.650  -77.662 1.00 41.48  ? 19  GLN C NE2 1 
ATOM   7243  N  N   . VAL D 1 20  ? -37.701 48.285  -80.833 1.00 23.25  ? 20  VAL C N   1 
ATOM   7244  C  CA  . VAL D 1 20  ? -38.412 47.583  -81.905 1.00 21.53  ? 20  VAL C CA  1 
ATOM   7245  C  C   . VAL D 1 20  ? -39.783 47.143  -81.389 1.00 26.20  ? 20  VAL C C   1 
ATOM   7246  O  O   . VAL D 1 20  ? -39.884 46.411  -80.389 1.00 25.20  ? 20  VAL C O   1 
ATOM   7247  C  CB  . VAL D 1 20  ? -37.600 46.382  -82.418 1.00 22.42  ? 20  VAL C CB  1 
ATOM   7248  C  CG1 . VAL D 1 20  ? -38.338 45.650  -83.544 1.00 22.96  ? 20  VAL C CG1 1 
ATOM   7249  C  CG2 . VAL D 1 20  ? -36.230 46.842  -82.886 1.00 22.01  ? 20  VAL C CG2 1 
ATOM   7250  N  N   . THR D 1 21  ? -40.835 47.539  -82.101 1.00 25.29  ? 21  THR C N   1 
ATOM   7251  C  CA  . THR D 1 21  ? -42.197 47.219  -81.702 1.00 30.13  ? 21  THR C CA  1 
ATOM   7252  C  C   . THR D 1 21  ? -42.924 46.481  -82.816 1.00 25.72  ? 21  THR C C   1 
ATOM   7253  O  O   . THR D 1 21  ? -42.817 46.842  -83.985 1.00 23.92  ? 21  THR C O   1 
ATOM   7254  C  CB  . THR D 1 21  ? -42.968 48.492  -81.329 1.00 25.93  ? 21  THR C CB  1 
ATOM   7255  O  OG1 . THR D 1 21  ? -42.292 49.153  -80.256 1.00 28.63  ? 21  THR C OG1 1 
ATOM   7256  C  CG2 . THR D 1 21  ? -44.384 48.148  -80.889 1.00 26.10  ? 21  THR C CG2 1 
ATOM   7257  N  N   . CYS D 1 22  ? -43.708 45.479  -82.445 1.00 27.27  ? 22  CYS C N   1 
ATOM   7258  C  CA  . CYS D 1 22  ? -44.509 44.747  -83.421 1.00 29.62  ? 22  CYS C CA  1 
ATOM   7259  C  C   . CYS D 1 22  ? -45.829 44.395  -82.740 1.00 31.09  ? 22  CYS C C   1 
ATOM   7260  O  O   . CYS D 1 22  ? -45.869 43.545  -81.845 1.00 32.57  ? 22  CYS C O   1 
ATOM   7261  C  CB  . CYS D 1 22  ? -43.752 43.522  -83.917 1.00 29.33  ? 22  CYS C CB  1 
ATOM   7262  S  SG  . CYS D 1 22  ? -44.422 42.813  -85.403 1.00 42.86  ? 22  CYS C SG  1 
ATOM   7263  N  N   . GLY D 1 23  ? -46.889 45.115  -83.104 1.00 30.64  ? 23  GLY C N   1 
ATOM   7264  C  CA  . GLY D 1 23  ? -48.156 44.973  -82.417 1.00 28.34  ? 23  GLY C CA  1 
ATOM   7265  C  C   . GLY D 1 23  ? -48.081 45.544  -81.019 1.00 35.60  ? 23  GLY C C   1 
ATOM   7266  O  O   . GLY D 1 23  ? -47.796 46.733  -80.835 1.00 36.67  ? 23  GLY C O   1 
ATOM   7267  N  N   . THR D 1 24  ? -48.331 44.698  -80.018 1.00 44.18  ? 24  THR C N   1 
ATOM   7268  C  CA  . THR D 1 24  ? -48.255 45.084  -78.615 1.00 39.37  ? 24  THR C CA  1 
ATOM   7269  C  C   . THR D 1 24  ? -46.948 44.647  -77.970 1.00 39.44  ? 24  THR C C   1 
ATOM   7270  O  O   . THR D 1 24  ? -46.789 44.795  -76.754 1.00 40.15  ? 24  THR C O   1 
ATOM   7271  C  CB  . THR D 1 24  ? -49.427 44.493  -77.824 1.00 42.25  ? 24  THR C CB  1 
ATOM   7272  O  OG1 . THR D 1 24  ? -49.527 43.095  -78.107 1.00 40.27  ? 24  THR C OG1 1 
ATOM   7273  C  CG2 . THR D 1 24  ? -50.743 45.175  -78.190 1.00 41.12  ? 24  THR C CG2 1 
ATOM   7274  N  N   . THR D 1 25  ? -46.013 44.115  -78.747 1.00 34.34  ? 25  THR C N   1 
ATOM   7275  C  CA  . THR D 1 25  ? -44.724 43.690  -78.224 1.00 35.08  ? 25  THR C CA  1 
ATOM   7276  C  C   . THR D 1 25  ? -43.660 44.731  -78.542 1.00 33.34  ? 25  THR C C   1 
ATOM   7277  O  O   . THR D 1 25  ? -43.510 45.155  -79.694 1.00 30.73  ? 25  THR C O   1 
ATOM   7278  C  CB  . THR D 1 25  ? -44.296 42.339  -78.799 1.00 35.63  ? 25  THR C CB  1 
ATOM   7279  O  OG1 . THR D 1 25  ? -45.361 41.389  -78.667 1.00 34.51  ? 25  THR C OG1 1 
ATOM   7280  C  CG2 . THR D 1 25  ? -43.060 41.841  -78.087 1.00 33.68  ? 25  THR C CG2 1 
ATOM   7281  N  N   . THR D 1 26  ? -42.928 45.135  -77.520 1.00 32.04  ? 26  THR C N   1 
ATOM   7282  C  CA  . THR D 1 26  ? -41.811 46.052  -77.664 1.00 28.85  ? 26  THR C CA  1 
ATOM   7283  C  C   . THR D 1 26  ? -40.612 45.393  -77.019 1.00 29.19  ? 26  THR C C   1 
ATOM   7284  O  O   . THR D 1 26  ? -40.742 44.806  -75.945 1.00 30.94  ? 26  THR C O   1 
ATOM   7285  C  CB  . THR D 1 26  ? -42.103 47.396  -77.004 1.00 27.62  ? 26  THR C CB  1 
ATOM   7286  O  OG1 . THR D 1 26  ? -43.150 48.047  -77.724 1.00 39.65  ? 26  THR C OG1 1 
ATOM   7287  C  CG2 . THR D 1 26  ? -40.858 48.285  -76.963 1.00 30.42  ? 26  THR C CG2 1 
ATOM   7288  N  N   . LEU D 1 27  ? -39.468 45.444  -77.685 1.00 27.48  ? 27  LEU C N   1 
ATOM   7289  C  CA  . LEU D 1 27  ? -38.232 45.008  -77.058 1.00 25.86  ? 27  LEU C CA  1 
ATOM   7290  C  C   . LEU D 1 27  ? -37.104 45.810  -77.688 1.00 26.52  ? 27  LEU C C   1 
ATOM   7291  O  O   . LEU D 1 27  ? -37.345 46.807  -78.382 1.00 26.45  ? 27  LEU C O   1 
ATOM   7292  C  CB  . LEU D 1 27  ? -38.032 43.487  -77.186 1.00 25.62  ? 27  LEU C CB  1 
ATOM   7293  C  CG  . LEU D 1 27  ? -38.254 42.815  -78.542 1.00 29.04  ? 27  LEU C CG  1 
ATOM   7294  C  CD1 . LEU D 1 27  ? -37.216 43.273  -79.562 1.00 21.73  ? 27  LEU C CD1 1 
ATOM   7295  C  CD2 . LEU D 1 27  ? -38.195 41.305  -78.401 1.00 26.44  ? 27  LEU C CD2 1 
ATOM   7296  N  N   . ASN D 1 28  ? -35.868 45.379  -77.434 1.00 23.84  ? 28  ASN C N   1 
ATOM   7297  C  CA  . ASN D 1 28  ? -34.691 46.108  -77.875 1.00 21.82  ? 28  ASN C CA  1 
ATOM   7298  C  C   . ASN D 1 28  ? -34.111 45.497  -79.141 1.00 19.57  ? 28  ASN C C   1 
ATOM   7299  O  O   . ASN D 1 28  ? -34.228 44.301  -79.379 1.00 25.87  ? 28  ASN C O   1 
ATOM   7300  C  CB  . ASN D 1 28  ? -33.626 46.138  -76.784 1.00 20.90  ? 28  ASN C CB  1 
ATOM   7301  C  CG  . ASN D 1 28  ? -34.156 46.675  -75.473 1.00 27.10  ? 28  ASN C CG  1 
ATOM   7302  O  OD1 . ASN D 1 28  ? -34.416 47.886  -75.337 1.00 22.02  ? 28  ASN C OD1 1 
ATOM   7303  N  ND2 . ASN D 1 28  ? -34.232 45.804  -74.470 1.00 27.48  ? 28  ASN C ND2 1 
ATOM   7304  N  N   . GLY D 1 29  ? -33.473 46.333  -79.955 1.00 22.02  ? 29  GLY C N   1 
ATOM   7305  C  CA  . GLY D 1 29  ? -32.758 45.854  -81.113 1.00 20.15  ? 29  GLY C CA  1 
ATOM   7306  C  C   . GLY D 1 29  ? -31.365 46.446  -81.158 1.00 18.30  ? 29  GLY C C   1 
ATOM   7307  O  O   . GLY D 1 29  ? -31.062 47.438  -80.488 1.00 20.04  ? 29  GLY C O   1 
ATOM   7308  N  N   . LEU D 1 30  ? -30.519 45.828  -81.976 1.00 16.90  ? 30  LEU C N   1 
ATOM   7309  C  CA  . LEU D 1 30  ? -29.141 46.271  -82.166 1.00 20.81  ? 30  LEU C CA  1 
ATOM   7310  C  C   . LEU D 1 30  ? -28.963 46.776  -83.593 1.00 19.81  ? 30  LEU C C   1 
ATOM   7311  O  O   . LEU D 1 30  ? -29.119 46.005  -84.554 1.00 18.25  ? 30  LEU C O   1 
ATOM   7312  C  CB  . LEU D 1 30  ? -28.149 45.149  -81.866 1.00 19.62  ? 30  LEU C CB  1 
ATOM   7313  C  CG  . LEU D 1 30  ? -26.686 45.563  -81.889 1.00 17.87  ? 30  LEU C CG  1 
ATOM   7314  C  CD1 . LEU D 1 30  ? -26.374 46.403  -80.665 1.00 16.70  ? 30  LEU C CD1 1 
ATOM   7315  C  CD2 . LEU D 1 30  ? -25.809 44.324  -81.922 1.00 17.23  ? 30  LEU C CD2 1 
ATOM   7316  N  N   . TRP D 1 31  ? -28.635 48.072  -83.719 1.00 20.36  ? 31  TRP C N   1 
ATOM   7317  C  CA  . TRP D 1 31  ? -28.551 48.782  -85.001 1.00 20.89  ? 31  TRP C CA  1 
ATOM   7318  C  C   . TRP D 1 31  ? -27.087 48.928  -85.412 1.00 20.31  ? 31  TRP C C   1 
ATOM   7319  O  O   . TRP D 1 31  ? -26.370 49.774  -84.876 1.00 18.31  ? 31  TRP C O   1 
ATOM   7320  C  CB  . TRP D 1 31  ? -29.214 50.158  -84.883 1.00 20.16  ? 31  TRP C CB  1 
ATOM   7321  C  CG  . TRP D 1 31  ? -29.342 50.992  -86.174 1.00 23.71  ? 31  TRP C CG  1 
ATOM   7322  C  CD1 . TRP D 1 31  ? -29.270 50.544  -87.473 1.00 23.33  ? 31  TRP C CD1 1 
ATOM   7323  C  CD2 . TRP D 1 31  ? -29.608 52.410  -86.259 1.00 22.59  ? 31  TRP C CD2 1 
ATOM   7324  N  NE1 . TRP D 1 31  ? -29.466 51.595  -88.353 1.00 21.67  ? 31  TRP C NE1 1 
ATOM   7325  C  CE2 . TRP D 1 31  ? -29.662 52.749  -87.638 1.00 24.01  ? 31  TRP C CE2 1 
ATOM   7326  C  CE3 . TRP D 1 31  ? -29.773 53.424  -85.305 1.00 17.95  ? 31  TRP C CE3 1 
ATOM   7327  C  CZ2 . TRP D 1 31  ? -29.900 54.068  -88.088 1.00 22.20  ? 31  TRP C CZ2 1 
ATOM   7328  C  CZ3 . TRP D 1 31  ? -30.002 54.739  -85.753 1.00 22.76  ? 31  TRP C CZ3 1 
ATOM   7329  C  CH2 . TRP D 1 31  ? -30.066 55.043  -87.138 1.00 19.70  ? 31  TRP C CH2 1 
ATOM   7330  N  N   . LEU D 1 32  ? -26.664 48.150  -86.402 1.00 20.66  ? 32  LEU C N   1 
ATOM   7331  C  CA  . LEU D 1 32  ? -25.311 48.195  -86.940 1.00 19.89  ? 32  LEU C CA  1 
ATOM   7332  C  C   . LEU D 1 32  ? -25.410 48.359  -88.445 1.00 24.94  ? 32  LEU C C   1 
ATOM   7333  O  O   . LEU D 1 32  ? -26.086 47.571  -89.115 1.00 24.25  ? 32  LEU C O   1 
ATOM   7334  C  CB  . LEU D 1 32  ? -24.525 46.926  -86.610 1.00 20.55  ? 32  LEU C CB  1 
ATOM   7335  C  CG  . LEU D 1 32  ? -24.394 46.587  -85.129 1.00 20.92  ? 32  LEU C CG  1 
ATOM   7336  C  CD1 . LEU D 1 32  ? -23.997 45.103  -84.915 1.00 21.48  ? 32  LEU C CD1 1 
ATOM   7337  C  CD2 . LEU D 1 32  ? -23.366 47.522  -84.530 1.00 21.82  ? 32  LEU C CD2 1 
ATOM   7338  N  N   . ASP D 1 33  ? -24.748 49.389  -88.970 1.00 23.71  ? 33  ASP C N   1 
ATOM   7339  C  CA  . ASP D 1 33  ? -24.843 49.762  -90.389 1.00 26.16  ? 33  ASP C CA  1 
ATOM   7340  C  C   . ASP D 1 33  ? -26.333 49.940  -90.696 1.00 21.60  ? 33  ASP C C   1 
ATOM   7341  O  O   . ASP D 1 33  ? -27.018 50.662  -89.962 1.00 22.92  ? 33  ASP C O   1 
ATOM   7342  C  CB  . ASP D 1 33  ? -24.091 48.743  -91.242 1.00 28.08  ? 33  ASP C CB  1 
ATOM   7343  C  CG  . ASP D 1 33  ? -22.658 48.534  -90.763 1.00 37.31  ? 33  ASP C CG  1 
ATOM   7344  O  OD1 . ASP D 1 33  ? -21.981 49.532  -90.415 1.00 37.13  ? 33  ASP C OD1 1 
ATOM   7345  O  OD2 . ASP D 1 33  ? -22.193 47.367  -90.747 1.00 43.57  ? 33  ASP C OD2 1 
ATOM   7346  N  N   . ASP D 1 34  ? -26.888 49.276  -91.706 1.00 19.70  ? 34  ASP C N   1 
ATOM   7347  C  CA  . ASP D 1 34  ? -28.292 49.446  -92.057 1.00 21.12  ? 34  ASP C CA  1 
ATOM   7348  C  C   . ASP D 1 34  ? -29.160 48.255  -91.628 1.00 23.40  ? 34  ASP C C   1 
ATOM   7349  O  O   . ASP D 1 34  ? -30.229 48.025  -92.198 1.00 25.93  ? 34  ASP C O   1 
ATOM   7350  C  CB  . ASP D 1 34  ? -28.410 49.698  -93.558 1.00 23.98  ? 34  ASP C CB  1 
ATOM   7351  C  CG  . ASP D 1 34  ? -27.829 48.557  -94.378 1.00 27.76  ? 34  ASP C CG  1 
ATOM   7352  O  OD1 . ASP D 1 34  ? -26.928 47.862  -93.849 1.00 23.90  ? 34  ASP C OD1 1 
ATOM   7353  O  OD2 . ASP D 1 34  ? -28.233 48.381  -95.546 1.00 26.41  ? 34  ASP C OD2 1 
ATOM   7354  N  N   . VAL D 1 35  ? -28.761 47.538  -90.575 1.00 21.67  ? 35  VAL C N   1 
ATOM   7355  C  CA  . VAL D 1 35  ? -29.500 46.375  -90.094 1.00 23.80  ? 35  VAL C CA  1 
ATOM   7356  C  C   . VAL D 1 35  ? -29.806 46.549  -88.612 1.00 22.11  ? 35  VAL C C   1 
ATOM   7357  O  O   . VAL D 1 35  ? -28.960 47.016  -87.841 1.00 22.78  ? 35  VAL C O   1 
ATOM   7358  C  CB  . VAL D 1 35  ? -28.724 45.058  -90.318 1.00 20.73  ? 35  VAL C CB  1 
ATOM   7359  C  CG1 . VAL D 1 35  ? -29.535 43.908  -89.793 1.00 22.11  ? 35  VAL C CG1 1 
ATOM   7360  C  CG2 . VAL D 1 35  ? -28.427 44.841  -91.774 1.00 12.87  ? 35  VAL C CG2 1 
ATOM   7361  N  N   . VAL D 1 36  ? -31.022 46.187  -88.219 1.00 18.50  ? 36  VAL C N   1 
ATOM   7362  C  CA  . VAL D 1 36  ? -31.423 46.109  -86.821 1.00 18.26  ? 36  VAL C CA  1 
ATOM   7363  C  C   . VAL D 1 36  ? -31.594 44.632  -86.478 1.00 19.65  ? 36  VAL C C   1 
ATOM   7364  O  O   . VAL D 1 36  ? -32.390 43.931  -87.118 1.00 24.22  ? 36  VAL C O   1 
ATOM   7365  C  CB  . VAL D 1 36  ? -32.729 46.881  -86.568 1.00 19.25  ? 36  VAL C CB  1 
ATOM   7366  C  CG1 . VAL D 1 36  ? -33.299 46.547  -85.202 1.00 16.03  ? 36  VAL C CG1 1 
ATOM   7367  C  CG2 . VAL D 1 36  ? -32.507 48.347  -86.704 1.00 16.48  ? 36  VAL C CG2 1 
ATOM   7368  N  N   . TYR D 1 37  ? -30.867 44.161  -85.468 1.00 21.66  ? 37  TYR C N   1 
ATOM   7369  C  CA  . TYR D 1 37  ? -30.982 42.785  -84.986 1.00 23.85  ? 37  TYR C CA  1 
ATOM   7370  C  C   . TYR D 1 37  ? -31.767 42.776  -83.685 1.00 24.32  ? 37  TYR C C   1 
ATOM   7371  O  O   . TYR D 1 37  ? -31.528 43.619  -82.815 1.00 24.08  ? 37  TYR C O   1 
ATOM   7372  C  CB  . TYR D 1 37  ? -29.616 42.143  -84.744 1.00 16.79  ? 37  TYR C CB  1 
ATOM   7373  C  CG  . TYR D 1 37  ? -28.667 42.218  -85.907 1.00 24.62  ? 37  TYR C CG  1 
ATOM   7374  C  CD1 . TYR D 1 37  ? -27.998 43.424  -86.211 1.00 20.96  ? 37  TYR C CD1 1 
ATOM   7375  C  CD2 . TYR D 1 37  ? -28.412 41.093  -86.696 1.00 18.17  ? 37  TYR C CD2 1 
ATOM   7376  C  CE1 . TYR D 1 37  ? -27.121 43.504  -87.274 1.00 20.38  ? 37  TYR C CE1 1 
ATOM   7377  C  CE2 . TYR D 1 37  ? -27.525 41.165  -87.763 1.00 20.94  ? 37  TYR C CE2 1 
ATOM   7378  C  CZ  . TYR D 1 37  ? -26.887 42.375  -88.046 1.00 22.27  ? 37  TYR C CZ  1 
ATOM   7379  O  OH  . TYR D 1 37  ? -26.010 42.456  -89.098 1.00 31.44  ? 37  TYR C OH  1 
ATOM   7380  N  N   . CYS D 1 38  ? -32.698 41.828  -83.563 1.00 18.82  ? 38  CYS C N   1 
ATOM   7381  C  CA  . CYS D 1 38  ? -33.516 41.699  -82.364 1.00 24.21  ? 38  CYS C CA  1 
ATOM   7382  C  C   . CYS D 1 38  ? -34.046 40.269  -82.285 1.00 25.48  ? 38  CYS C C   1 
ATOM   7383  O  O   . CYS D 1 38  ? -33.997 39.514  -83.274 1.00 21.70  ? 38  CYS C O   1 
ATOM   7384  C  CB  . CYS D 1 38  ? -34.671 42.709  -82.367 1.00 19.55  ? 38  CYS C CB  1 
ATOM   7385  S  SG  . CYS D 1 38  ? -35.936 42.373  -83.550 1.00 23.67  ? 38  CYS C SG  1 
ATOM   7386  N  N   . PRO D 1 39  ? -34.569 39.860  -81.127 1.00 25.90  ? 39  PRO C N   1 
ATOM   7387  C  CA  . PRO D 1 39  ? -35.121 38.500  -81.037 1.00 30.50  ? 39  PRO C CA  1 
ATOM   7388  C  C   . PRO D 1 39  ? -36.355 38.384  -81.916 1.00 27.81  ? 39  PRO C C   1 
ATOM   7389  O  O   . PRO D 1 39  ? -37.158 39.311  -82.004 1.00 21.53  ? 39  PRO C O   1 
ATOM   7390  C  CB  . PRO D 1 39  ? -35.454 38.332  -79.546 1.00 24.88  ? 39  PRO C CB  1 
ATOM   7391  C  CG  . PRO D 1 39  ? -34.624 39.396  -78.844 1.00 25.23  ? 39  PRO C CG  1 
ATOM   7392  C  CD  . PRO D 1 39  ? -34.564 40.542  -79.821 1.00 23.56  ? 39  PRO C CD  1 
ATOM   7393  N  N   . ARG D 1 40  ? -36.481 37.239  -82.598 1.00 27.18  ? 40  ARG C N   1 
ATOM   7394  C  CA  . ARG D 1 40  ? -37.606 37.029  -83.503 1.00 25.64  ? 40  ARG C CA  1 
ATOM   7395  C  C   . ARG D 1 40  ? -38.944 37.005  -82.774 1.00 26.34  ? 40  ARG C C   1 
ATOM   7396  O  O   . ARG D 1 40  ? -39.970 37.297  -83.396 1.00 26.21  ? 40  ARG C O   1 
ATOM   7397  C  CB  . ARG D 1 40  ? -37.429 35.730  -84.290 1.00 28.70  ? 40  ARG C CB  1 
ATOM   7398  C  CG  . ARG D 1 40  ? -37.626 34.431  -83.495 1.00 30.84  ? 40  ARG C CG  1 
ATOM   7399  C  CD  . ARG D 1 40  ? -37.403 33.256  -84.434 1.00 28.38  ? 40  ARG C CD  1 
ATOM   7400  N  NE  . ARG D 1 40  ? -37.461 31.967  -83.764 1.00 26.70  ? 40  ARG C NE  1 
ATOM   7401  C  CZ  . ARG D 1 40  ? -37.336 30.805  -84.394 1.00 33.62  ? 40  ARG C CZ  1 
ATOM   7402  N  NH1 . ARG D 1 40  ? -37.151 30.752  -85.706 1.00 28.45  ? 40  ARG C NH1 1 
ATOM   7403  N  NH2 . ARG D 1 40  ? -37.421 29.669  -83.696 1.00 26.73  ? 40  ARG C NH2 1 
ATOM   7404  N  N   . HIS D 1 41  ? -38.965 36.669  -81.447 1.00 27.24  ? 41  HIS C N   1 
ATOM   7405  C  CA  . HIS D 1 41  ? -40.271 36.614  -80.761 1.00 28.59  ? 41  HIS C CA  1 
ATOM   7406  C  C   . HIS D 1 41  ? -40.885 38.010  -80.536 1.00 28.66  ? 41  HIS C C   1 
ATOM   7407  O  O   . HIS D 1 41  ? -41.914 38.070  -79.821 1.00 28.51  ? 41  HIS C O   1 
ATOM   7408  C  CB  . HIS D 1 41  ? -40.199 35.844  -79.427 1.00 26.88  ? 41  HIS C CB  1 
ATOM   7409  C  CG  . HIS D 1 41  ? -39.390 36.511  -78.353 1.00 26.20  ? 41  HIS C CG  1 
ATOM   7410  N  ND1 . HIS D 1 41  ? -38.088 36.155  -78.075 1.00 23.11  ? 41  HIS C ND1 1 
ATOM   7411  C  CD2 . HIS D 1 41  ? -39.718 37.467  -77.448 1.00 28.57  ? 41  HIS C CD2 1 
ATOM   7412  C  CE1 . HIS D 1 41  ? -37.634 36.896  -77.077 1.00 29.70  ? 41  HIS C CE1 1 
ATOM   7413  N  NE2 . HIS D 1 41  ? -38.603 37.703  -76.680 1.00 25.79  ? 41  HIS C NE2 1 
ATOM   7414  N  N   . VAL D 1 42  ? -40.292 39.058  -81.122 1.00 26.38  ? 42  VAL C N   1 
ATOM   7415  C  CA  . VAL D 1 42  ? -40.965 40.348  -81.248 1.00 26.65  ? 42  VAL C CA  1 
ATOM   7416  C  C   . VAL D 1 42  ? -42.255 40.236  -82.067 1.00 28.96  ? 42  VAL C C   1 
ATOM   7417  O  O   . VAL D 1 42  ? -43.165 41.057  -81.900 1.00 30.13  ? 42  VAL C O   1 
ATOM   7418  C  CB  . VAL D 1 42  ? -39.987 41.412  -81.839 1.00 30.81  ? 42  VAL C CB  1 
ATOM   7419  C  CG1 . VAL D 1 42  ? -39.681 41.178  -83.319 1.00 24.73  ? 42  VAL C CG1 1 
ATOM   7420  C  CG2 . VAL D 1 42  ? -40.511 42.868  -81.625 1.00 33.31  ? 42  VAL C CG2 1 
ATOM   7421  N  N   . ILE D 1 43  ? -42.385 39.211  -82.920 1.00 28.43  ? 43  ILE C N   1 
ATOM   7422  C  CA  . ILE D 1 43  ? -43.580 39.085  -83.757 1.00 32.99  ? 43  ILE C CA  1 
ATOM   7423  C  C   . ILE D 1 43  ? -44.704 38.273  -83.102 1.00 33.59  ? 43  ILE C C   1 
ATOM   7424  O  O   . ILE D 1 43  ? -45.805 38.193  -83.664 1.00 34.79  ? 43  ILE C O   1 
ATOM   7425  C  CB  . ILE D 1 43  ? -43.212 38.509  -85.143 1.00 31.73  ? 43  ILE C CB  1 
ATOM   7426  C  CG1 . ILE D 1 43  ? -42.961 37.003  -85.086 1.00 27.70  ? 43  ILE C CG1 1 
ATOM   7427  C  CG2 . ILE D 1 43  ? -41.983 39.229  -85.715 1.00 31.54  ? 43  ILE C CG2 1 
ATOM   7428  C  CD1 . ILE D 1 43  ? -42.438 36.411  -86.425 1.00 23.79  ? 43  ILE C CD1 1 
ATOM   7429  N  N   . CYS D 1 44  ? -44.482 37.708  -81.921 1.00 36.22  ? 44  CYS C N   1 
ATOM   7430  C  CA  . CYS D 1 44  ? -45.501 36.942  -81.211 1.00 39.93  ? 44  CYS C CA  1 
ATOM   7431  C  C   . CYS D 1 44  ? -46.379 37.853  -80.359 1.00 39.27  ? 44  CYS C C   1 
ATOM   7432  O  O   . CYS D 1 44  ? -45.953 38.911  -79.895 1.00 41.87  ? 44  CYS C O   1 
ATOM   7433  C  CB  . CYS D 1 44  ? -44.868 35.888  -80.291 1.00 35.48  ? 44  CYS C CB  1 
ATOM   7434  S  SG  . CYS D 1 44  ? -43.844 34.604  -81.057 1.00 39.67  ? 44  CYS C SG  1 
ATOM   7435  N  N   . THR D 1 45  ? -47.618 37.428  -80.163 1.00 53.94  ? 45  THR C N   1 
ATOM   7436  C  CA  . THR D 1 45  ? -48.472 37.941  -79.101 1.00 59.03  ? 45  THR C CA  1 
ATOM   7437  C  C   . THR D 1 45  ? -48.279 37.097  -77.835 1.00 65.08  ? 45  THR C C   1 
ATOM   7438  O  O   . THR D 1 45  ? -47.652 36.034  -77.859 1.00 61.07  ? 45  THR C O   1 
ATOM   7439  C  CB  . THR D 1 45  ? -49.936 37.935  -79.548 1.00 65.76  ? 45  THR C CB  1 
ATOM   7440  O  OG1 . THR D 1 45  ? -50.422 36.586  -79.566 1.00 70.48  ? 45  THR C OG1 1 
ATOM   7441  C  CG2 . THR D 1 45  ? -50.073 38.541  -80.954 1.00 55.09  ? 45  THR C CG2 1 
ATOM   7442  N  N   . SER D 1 46  ? -48.829 37.578  -76.712 1.00 61.12  ? 46  SER C N   1 
ATOM   7443  C  CA  . SER D 1 46  ? -48.783 36.781  -75.488 1.00 66.99  ? 46  SER C CA  1 
ATOM   7444  C  C   . SER D 1 46  ? -49.497 35.447  -75.662 1.00 74.70  ? 46  SER C C   1 
ATOM   7445  O  O   . SER D 1 46  ? -49.175 34.477  -74.967 1.00 71.97  ? 46  SER C O   1 
ATOM   7446  C  CB  . SER D 1 46  ? -49.395 37.546  -74.316 1.00 63.09  ? 46  SER C CB  1 
ATOM   7447  O  OG  . SER D 1 46  ? -48.495 38.511  -73.805 1.00 71.79  ? 46  SER C OG  1 
ATOM   7448  N  N   . GLU D 1 47  ? -50.463 35.382  -76.580 1.00 76.34  ? 47  GLU C N   1 
ATOM   7449  C  CA  . GLU D 1 47  ? -51.207 34.162  -76.864 1.00 74.27  ? 47  GLU C CA  1 
ATOM   7450  C  C   . GLU D 1 47  ? -50.297 33.073  -77.413 1.00 76.33  ? 47  GLU C C   1 
ATOM   7451  O  O   . GLU D 1 47  ? -50.058 32.056  -76.753 1.00 77.94  ? 47  GLU C O   1 
ATOM   7452  C  CB  . GLU D 1 47  ? -52.319 34.437  -77.885 1.00 80.07  ? 47  GLU C CB  1 
ATOM   7453  C  CG  . GLU D 1 47  ? -53.197 35.651  -77.582 1.00 89.30  ? 47  GLU C CG  1 
ATOM   7454  C  CD  . GLU D 1 47  ? -53.802 36.263  -78.844 1.00 86.48  ? 47  GLU C CD  1 
ATOM   7455  O  OE1 . GLU D 1 47  ? -53.264 36.012  -79.945 1.00 81.60  ? 47  GLU C OE1 1 
ATOM   7456  O  OE2 . GLU D 1 47  ? -54.800 37.009  -78.732 1.00 86.11  ? 47  GLU C OE2 1 
ATOM   7457  N  N   . ASP D 1 48  ? -49.779 33.285  -78.623 1.00 75.28  ? 48  ASP C N   1 
ATOM   7458  C  CA  . ASP D 1 48  ? -49.069 32.232  -79.340 1.00 78.97  ? 48  ASP C CA  1 
ATOM   7459  C  C   . ASP D 1 48  ? -47.646 32.044  -78.828 1.00 69.29  ? 48  ASP C C   1 
ATOM   7460  O  O   . ASP D 1 48  ? -46.751 31.687  -79.600 1.00 68.32  ? 48  ASP C O   1 
ATOM   7461  C  CB  . ASP D 1 48  ? -49.051 32.532  -80.841 1.00 78.19  ? 48  ASP C CB  1 
ATOM   7462  C  CG  . ASP D 1 48  ? -50.375 32.212  -81.519 1.00 83.18  ? 48  ASP C CG  1 
ATOM   7463  O  OD1 . ASP D 1 48  ? -51.356 31.901  -80.806 1.00 80.14  ? 48  ASP C OD1 1 
ATOM   7464  O  OD2 . ASP D 1 48  ? -50.435 32.282  -82.767 1.00 90.11  ? 48  ASP C OD2 1 
ATOM   7465  N  N   . MET D 1 49  ? -47.418 32.279  -77.536 1.00 72.12  ? 49  MET C N   1 
ATOM   7466  C  CA  . MET D 1 49  ? -46.102 32.026  -76.967 1.00 65.83  ? 49  MET C CA  1 
ATOM   7467  C  C   . MET D 1 49  ? -45.904 30.579  -76.542 1.00 55.43  ? 49  MET C C   1 
ATOM   7468  O  O   . MET D 1 49  ? -44.756 30.163  -76.363 1.00 54.73  ? 49  MET C O   1 
ATOM   7469  C  CB  . MET D 1 49  ? -45.852 32.955  -75.780 1.00 63.11  ? 49  MET C CB  1 
ATOM   7470  C  CG  . MET D 1 49  ? -45.285 34.304  -76.168 1.00 64.35  ? 49  MET C CG  1 
ATOM   7471  S  SD  . MET D 1 49  ? -43.569 34.140  -76.700 1.00 61.06  ? 49  MET C SD  1 
ATOM   7472  C  CE  . MET D 1 49  ? -43.081 35.856  -76.844 1.00 51.15  ? 49  MET C CE  1 
ATOM   7473  N  N   . LEU D 1 50  ? -46.981 29.803  -76.392 1.00 61.52  ? 50  LEU C N   1 
ATOM   7474  C  CA  . LEU D 1 50  ? -46.826 28.411  -75.981 1.00 60.17  ? 50  LEU C CA  1 
ATOM   7475  C  C   . LEU D 1 50  ? -46.128 27.602  -77.059 1.00 60.21  ? 50  LEU C C   1 
ATOM   7476  O  O   . LEU D 1 50  ? -45.201 26.837  -76.773 1.00 58.96  ? 50  LEU C O   1 
ATOM   7477  C  CB  . LEU D 1 50  ? -48.179 27.780  -75.656 1.00 66.49  ? 50  LEU C CB  1 
ATOM   7478  C  CG  . LEU D 1 50  ? -48.799 28.014  -74.283 1.00 71.35  ? 50  LEU C CG  1 
ATOM   7479  C  CD1 . LEU D 1 50  ? -50.157 27.329  -74.192 1.00 75.08  ? 50  LEU C CD1 1 
ATOM   7480  C  CD2 . LEU D 1 50  ? -47.860 27.479  -73.219 1.00 68.88  ? 50  LEU C CD2 1 
ATOM   7481  N  N   . ASN D 1 51  ? -46.564 27.754  -78.308 1.00 64.35  ? 51  ASN C N   1 
ATOM   7482  C  CA  . ASN D 1 51  ? -45.971 27.027  -79.430 1.00 63.99  ? 51  ASN C CA  1 
ATOM   7483  C  C   . ASN D 1 51  ? -46.089 27.866  -80.690 1.00 61.42  ? 51  ASN C C   1 
ATOM   7484  O  O   . ASN D 1 51  ? -46.982 27.664  -81.521 1.00 58.69  ? 51  ASN C O   1 
ATOM   7485  C  CB  . ASN D 1 51  ? -46.622 25.657  -79.600 1.00 60.67  ? 51  ASN C CB  1 
ATOM   7486  C  CG  . ASN D 1 51  ? -45.795 24.562  -78.965 1.00 64.91  ? 51  ASN C CG  1 
ATOM   7487  O  OD1 . ASN D 1 51  ? -44.837 24.073  -79.562 1.00 68.34  ? 51  ASN C OD1 1 
ATOM   7488  N  ND2 . ASN D 1 51  ? -46.133 24.203  -77.728 1.00 52.57  ? 51  ASN C ND2 1 
ATOM   7489  N  N   . PRO D 1 52  ? -45.188 28.831  -80.867 1.00 59.30  ? 52  PRO C N   1 
ATOM   7490  C  CA  . PRO D 1 52  ? -45.298 29.756  -82.001 1.00 51.01  ? 52  PRO C CA  1 
ATOM   7491  C  C   . PRO D 1 52  ? -44.696 29.169  -83.269 1.00 42.85  ? 52  PRO C C   1 
ATOM   7492  O  O   . PRO D 1 52  ? -43.584 28.640  -83.268 1.00 40.59  ? 52  PRO C O   1 
ATOM   7493  C  CB  . PRO D 1 52  ? -44.513 30.984  -81.531 1.00 41.58  ? 52  PRO C CB  1 
ATOM   7494  C  CG  . PRO D 1 52  ? -43.500 30.426  -80.583 1.00 47.26  ? 52  PRO C CG  1 
ATOM   7495  C  CD  . PRO D 1 52  ? -44.098 29.200  -79.945 1.00 52.50  ? 52  PRO C CD  1 
ATOM   7496  N  N   . ASN D 1 53  ? -45.437 29.286  -84.360 1.00 40.61  ? 53  ASN C N   1 
ATOM   7497  C  CA  . ASN D 1 53  ? -44.936 28.948  -85.686 1.00 41.67  ? 53  ASN C CA  1 
ATOM   7498  C  C   . ASN D 1 53  ? -44.376 30.238  -86.280 1.00 37.57  ? 53  ASN C C   1 
ATOM   7499  O  O   . ASN D 1 53  ? -45.097 31.049  -86.857 1.00 35.20  ? 53  ASN C O   1 
ATOM   7500  C  CB  . ASN D 1 53  ? -46.052 28.320  -86.520 1.00 43.70  ? 53  ASN C CB  1 
ATOM   7501  C  CG  . ASN D 1 53  ? -45.571 27.781  -87.863 1.00 47.24  ? 53  ASN C CG  1 
ATOM   7502  O  OD1 . ASN D 1 53  ? -44.621 28.297  -88.467 1.00 46.14  ? 53  ASN C OD1 1 
ATOM   7503  N  ND2 . ASN D 1 53  ? -46.217 26.713  -88.323 1.00 52.31  ? 53  ASN C ND2 1 
ATOM   7504  N  N   . TYR D 1 54  ? -43.066 30.436  -86.107 1.00 39.80  ? 54  TYR C N   1 
ATOM   7505  C  CA  . TYR D 1 54  ? -42.445 31.717  -86.438 1.00 38.31  ? 54  TYR C CA  1 
ATOM   7506  C  C   . TYR D 1 54  ? -42.491 32.007  -87.931 1.00 36.22  ? 54  TYR C C   1 
ATOM   7507  O  O   . TYR D 1 54  ? -42.662 33.161  -88.336 1.00 39.07  ? 54  TYR C O   1 
ATOM   7508  C  CB  . TYR D 1 54  ? -41.005 31.755  -85.927 1.00 34.77  ? 54  TYR C CB  1 
ATOM   7509  C  CG  . TYR D 1 54  ? -40.898 32.011  -84.433 1.00 40.78  ? 54  TYR C CG  1 
ATOM   7510  C  CD1 . TYR D 1 54  ? -41.060 33.300  -83.916 1.00 30.89  ? 54  TYR C CD1 1 
ATOM   7511  C  CD2 . TYR D 1 54  ? -40.643 30.966  -83.537 1.00 34.63  ? 54  TYR C CD2 1 
ATOM   7512  C  CE1 . TYR D 1 54  ? -40.963 33.539  -82.569 1.00 28.80  ? 54  TYR C CE1 1 
ATOM   7513  C  CE2 . TYR D 1 54  ? -40.535 31.197  -82.179 1.00 29.30  ? 54  TYR C CE2 1 
ATOM   7514  C  CZ  . TYR D 1 54  ? -40.700 32.483  -81.698 1.00 36.52  ? 54  TYR C CZ  1 
ATOM   7515  O  OH  . TYR D 1 54  ? -40.594 32.719  -80.341 1.00 32.11  ? 54  TYR C OH  1 
ATOM   7516  N  N   . GLU D 1 55  ? -42.297 30.985  -88.764 1.00 44.93  ? 55  GLU C N   1 
ATOM   7517  C  CA  . GLU D 1 55  ? -42.424 31.163  -90.208 1.00 44.24  ? 55  GLU C CA  1 
ATOM   7518  C  C   . GLU D 1 55  ? -43.824 31.630  -90.583 1.00 44.97  ? 55  GLU C C   1 
ATOM   7519  O  O   . GLU D 1 55  ? -43.987 32.505  -91.441 1.00 42.36  ? 55  GLU C O   1 
ATOM   7520  C  CB  . GLU D 1 55  ? -42.100 29.853  -90.930 1.00 45.62  ? 55  GLU C CB  1 
ATOM   7521  C  CG  . GLU D 1 55  ? -42.544 29.806  -92.386 1.00 55.53  ? 55  GLU C CG  1 
ATOM   7522  C  CD  . GLU D 1 55  ? -42.738 28.386  -92.898 1.00 62.95  ? 55  GLU C CD  1 
ATOM   7523  O  OE1 . GLU D 1 55  ? -42.835 27.463  -92.061 1.00 60.87  ? 55  GLU C OE1 1 
ATOM   7524  O  OE2 . GLU D 1 55  ? -42.796 28.196  -94.135 1.00 67.43  ? 55  GLU C OE2 1 
ATOM   7525  N  N   . ASP D 1 56  ? -44.851 31.029  -89.977 1.00 44.25  ? 56  ASP C N   1 
ATOM   7526  C  CA  . ASP D 1 56  ? -46.221 31.438  -90.267 1.00 49.21  ? 56  ASP C CA  1 
ATOM   7527  C  C   . ASP D 1 56  ? -46.499 32.852  -89.758 1.00 42.95  ? 56  ASP C C   1 
ATOM   7528  O  O   . ASP D 1 56  ? -47.151 33.641  -90.449 1.00 47.92  ? 56  ASP C O   1 
ATOM   7529  C  CB  . ASP D 1 56  ? -47.213 30.419  -89.693 1.00 50.86  ? 56  ASP C CB  1 
ATOM   7530  C  CG  . ASP D 1 56  ? -47.232 29.080  -90.485 1.00 65.13  ? 56  ASP C CG  1 
ATOM   7531  O  OD1 . ASP D 1 56  ? -46.516 28.941  -91.511 1.00 60.54  ? 56  ASP C OD1 1 
ATOM   7532  O  OD2 . ASP D 1 56  ? -47.974 28.156  -90.076 1.00 62.85  ? 56  ASP C OD2 1 
ATOM   7533  N  N   . LEU D 1 57  ? -46.023 33.191  -88.554 1.00 35.87  ? 57  LEU C N   1 
ATOM   7534  C  CA  . LEU D 1 57  ? -46.223 34.546  -88.035 1.00 40.17  ? 57  LEU C CA  1 
ATOM   7535  C  C   . LEU D 1 57  ? -45.497 35.577  -88.895 1.00 39.57  ? 57  LEU C C   1 
ATOM   7536  O  O   . LEU D 1 57  ? -46.015 36.672  -89.133 1.00 38.19  ? 57  LEU C O   1 
ATOM   7537  C  CB  . LEU D 1 57  ? -45.771 34.641  -86.569 1.00 32.97  ? 57  LEU C CB  1 
ATOM   7538  C  CG  . LEU D 1 57  ? -46.519 33.842  -85.476 1.00 35.08  ? 57  LEU C CG  1 
ATOM   7539  C  CD1 . LEU D 1 57  ? -45.708 33.746  -84.178 1.00 28.20  ? 57  LEU C CD1 1 
ATOM   7540  C  CD2 . LEU D 1 57  ? -47.897 34.400  -85.181 1.00 30.92  ? 57  LEU C CD2 1 
ATOM   7541  N  N   . LEU D 1 58  ? -44.306 35.236  -89.393 1.00 42.14  ? 58  LEU C N   1 
ATOM   7542  C  CA  . LEU D 1 58  ? -43.498 36.208  -90.126 1.00 40.43  ? 58  LEU C CA  1 
ATOM   7543  C  C   . LEU D 1 58  ? -44.094 36.531  -91.492 1.00 43.23  ? 58  LEU C C   1 
ATOM   7544  O  O   . LEU D 1 58  ? -44.046 37.683  -91.943 1.00 39.85  ? 58  LEU C O   1 
ATOM   7545  C  CB  . LEU D 1 58  ? -42.068 35.700  -90.268 1.00 35.57  ? 58  LEU C CB  1 
ATOM   7546  C  CG  . LEU D 1 58  ? -41.143 36.746  -90.877 1.00 39.80  ? 58  LEU C CG  1 
ATOM   7547  C  CD1 . LEU D 1 58  ? -41.227 38.034  -90.077 1.00 31.64  ? 58  LEU C CD1 1 
ATOM   7548  C  CD2 . LEU D 1 58  ? -39.719 36.220  -90.894 1.00 37.76  ? 58  LEU C CD2 1 
ATOM   7549  N  N   . ILE D 1 59  ? -44.662 35.529  -92.168 1.00 44.51  ? 59  ILE C N   1 
ATOM   7550  C  CA  . ILE D 1 59  ? -45.195 35.744  -93.510 1.00 47.97  ? 59  ILE C CA  1 
ATOM   7551  C  C   . ILE D 1 59  ? -46.398 36.687  -93.501 1.00 48.07  ? 59  ILE C C   1 
ATOM   7552  O  O   . ILE D 1 59  ? -46.724 37.282  -94.535 1.00 48.52  ? 59  ILE C O   1 
ATOM   7553  C  CB  . ILE D 1 59  ? -45.547 34.383  -94.144 1.00 50.08  ? 59  ILE C CB  1 
ATOM   7554  C  CG1 . ILE D 1 59  ? -45.572 34.491  -95.668 1.00 53.43  ? 59  ILE C CG1 1 
ATOM   7555  C  CG2 . ILE D 1 59  ? -46.876 33.853  -93.606 1.00 53.20  ? 59  ILE C CG2 1 
ATOM   7556  C  CD1 . ILE D 1 59  ? -44.274 35.030  -96.252 1.00 54.16  ? 59  ILE C CD1 1 
ATOM   7557  N  N   . ARG D 1 60  ? -47.071 36.829  -92.356 1.00 47.40  ? 60  ARG C N   1 
ATOM   7558  C  CA  . ARG D 1 60  ? -48.205 37.727  -92.168 1.00 42.54  ? 60  ARG C CA  1 
ATOM   7559  C  C   . ARG D 1 60  ? -47.804 39.172  -91.894 1.00 45.80  ? 60  ARG C C   1 
ATOM   7560  O  O   . ARG D 1 60  ? -48.693 40.016  -91.756 1.00 50.01  ? 60  ARG C O   1 
ATOM   7561  C  CB  . ARG D 1 60  ? -49.086 37.204  -91.026 1.00 45.58  ? 60  ARG C CB  1 
ATOM   7562  C  CG  . ARG D 1 60  ? -49.658 35.812  -91.317 1.00 54.87  ? 60  ARG C CG  1 
ATOM   7563  C  CD  . ARG D 1 60  ? -50.995 35.522  -90.644 1.00 54.33  ? 60  ARG C CD  1 
ATOM   7564  N  NE  . ARG D 1 60  ? -50.799 34.654  -89.491 1.00 52.91  ? 60  ARG C NE  1 
ATOM   7565  C  CZ  . ARG D 1 60  ? -50.741 33.331  -89.560 1.00 59.26  ? 60  ARG C CZ  1 
ATOM   7566  N  NH1 . ARG D 1 60  ? -50.894 32.692  -90.711 1.00 57.37  ? 60  ARG C NH1 1 
ATOM   7567  N  NH2 . ARG D 1 60  ? -50.515 32.631  -88.449 1.00 54.06  ? 60  ARG C NH2 1 
ATOM   7568  N  N   . LYS D 1 61  ? -46.507 39.474  -91.772 1.00 48.85  ? 61  LYS C N   1 
ATOM   7569  C  CA  . LYS D 1 61  ? -46.013 40.817  -91.474 1.00 42.07  ? 61  LYS C CA  1 
ATOM   7570  C  C   . LYS D 1 61  ? -45.426 41.480  -92.714 1.00 36.43  ? 61  LYS C C   1 
ATOM   7571  O  O   . LYS D 1 61  ? -44.932 40.816  -93.628 1.00 41.47  ? 61  LYS C O   1 
ATOM   7572  C  CB  . LYS D 1 61  ? -44.940 40.802  -90.376 1.00 36.48  ? 61  LYS C CB  1 
ATOM   7573  C  CG  . LYS D 1 61  ? -45.312 40.151  -89.058 1.00 38.40  ? 61  LYS C CG  1 
ATOM   7574  C  CD  . LYS D 1 61  ? -46.132 41.085  -88.192 1.00 40.68  ? 61  LYS C CD  1 
ATOM   7575  C  CE  . LYS D 1 61  ? -46.529 40.425  -86.879 1.00 38.27  ? 61  LYS C CE  1 
ATOM   7576  N  NZ  . LYS D 1 61  ? -47.616 41.171  -86.170 1.00 41.84  ? 61  LYS C NZ  1 
ATOM   7577  N  N   . SER D 1 62  ? -45.470 42.804  -92.723 1.00 35.28  ? 62  SER C N   1 
ATOM   7578  C  CA  . SER D 1 62  ? -44.823 43.617  -93.741 1.00 30.61  ? 62  SER C CA  1 
ATOM   7579  C  C   . SER D 1 62  ? -43.753 44.491  -93.105 1.00 25.83  ? 62  SER C C   1 
ATOM   7580  O  O   . SER D 1 62  ? -43.705 44.672  -91.887 1.00 22.16  ? 62  SER C O   1 
ATOM   7581  C  CB  . SER D 1 62  ? -45.842 44.508  -94.460 1.00 31.24  ? 62  SER C CB  1 
ATOM   7582  O  OG  . SER D 1 62  ? -46.821 43.733  -95.115 1.00 35.01  ? 62  SER C OG  1 
ATOM   7583  N  N   . ASN D 1 63  ? -42.920 45.080  -93.965 1.00 28.31  ? 63  ASN C N   1 
ATOM   7584  C  CA  . ASN D 1 63  ? -41.897 46.005  -93.489 1.00 25.52  ? 63  ASN C CA  1 
ATOM   7585  C  C   . ASN D 1 63  ? -42.485 47.085  -92.583 1.00 22.76  ? 63  ASN C C   1 
ATOM   7586  O  O   . ASN D 1 63  ? -41.923 47.369  -91.525 1.00 26.42  ? 63  ASN C O   1 
ATOM   7587  C  CB  . ASN D 1 63  ? -41.168 46.648  -94.679 1.00 28.08  ? 63  ASN C CB  1 
ATOM   7588  C  CG  . ASN D 1 63  ? -40.234 45.674  -95.408 1.00 27.78  ? 63  ASN C CG  1 
ATOM   7589  O  OD1 . ASN D 1 63  ? -39.722 44.710  -94.822 1.00 24.61  ? 63  ASN C OD1 1 
ATOM   7590  N  ND2 . ASN D 1 63  ? -40.010 45.928  -96.692 1.00 24.65  ? 63  ASN C ND2 1 
ATOM   7591  N  N   . HIS D 1 64  ? -43.644 47.655  -92.941 1.00 24.17  ? 64  HIS C N   1 
ATOM   7592  C  CA  . HIS D 1 64  ? -44.182 48.760  -92.147 1.00 22.12  ? 64  HIS C CA  1 
ATOM   7593  C  C   . HIS D 1 64  ? -44.829 48.317  -90.839 1.00 28.56  ? 64  HIS C C   1 
ATOM   7594  O  O   . HIS D 1 64  ? -45.152 49.181  -90.018 1.00 25.25  ? 64  HIS C O   1 
ATOM   7595  C  CB  . HIS D 1 64  ? -45.182 49.607  -92.958 1.00 25.74  ? 64  HIS C CB  1 
ATOM   7596  C  CG  . HIS D 1 64  ? -46.511 48.957  -93.196 1.00 28.07  ? 64  HIS C CG  1 
ATOM   7597  N  ND1 . HIS D 1 64  ? -46.783 48.209  -94.321 1.00 30.28  ? 64  HIS C ND1 1 
ATOM   7598  C  CD2 . HIS D 1 64  ? -47.650 48.948  -92.459 1.00 27.26  ? 64  HIS C CD2 1 
ATOM   7599  C  CE1 . HIS D 1 64  ? -48.023 47.752  -94.261 1.00 24.40  ? 64  HIS C CE1 1 
ATOM   7600  N  NE2 . HIS D 1 64  ? -48.571 48.185  -93.141 1.00 25.17  ? 64  HIS C NE2 1 
ATOM   7601  N  N   . ASN D 1 65  ? -44.987 47.007  -90.598 1.00 29.01  ? 65  ASN C N   1 
ATOM   7602  C  CA  . ASN D 1 65  ? -45.430 46.526  -89.291 1.00 28.90  ? 65  ASN C CA  1 
ATOM   7603  C  C   . ASN D 1 65  ? -44.307 46.497  -88.252 1.00 27.33  ? 65  ASN C C   1 
ATOM   7604  O  O   . ASN D 1 65  ? -44.603 46.321  -87.065 1.00 28.36  ? 65  ASN C O   1 
ATOM   7605  C  CB  . ASN D 1 65  ? -46.047 45.118  -89.381 1.00 27.50  ? 65  ASN C CB  1 
ATOM   7606  C  CG  . ASN D 1 65  ? -47.329 45.072  -90.208 1.00 31.53  ? 65  ASN C CG  1 
ATOM   7607  O  OD1 . ASN D 1 65  ? -47.547 44.142  -90.981 1.00 36.71  ? 65  ASN C OD1 1 
ATOM   7608  N  ND2 . ASN D 1 65  ? -48.179 46.075  -90.045 1.00 32.54  ? 65  ASN C ND2 1 
ATOM   7609  N  N   . PHE D 1 66  ? -43.032 46.645  -88.652 1.00 21.76  ? 66  PHE C N   1 
ATOM   7610  C  CA  . PHE D 1 66  ? -41.917 46.661  -87.701 1.00 21.17  ? 66  PHE C CA  1 
ATOM   7611  C  C   . PHE D 1 66  ? -41.599 48.128  -87.414 1.00 29.25  ? 66  PHE C C   1 
ATOM   7612  O  O   . PHE D 1 66  ? -40.950 48.804  -88.218 1.00 22.77  ? 66  PHE C O   1 
ATOM   7613  C  CB  . PHE D 1 66  ? -40.699 45.919  -88.252 1.00 24.28  ? 66  PHE C CB  1 
ATOM   7614  C  CG  . PHE D 1 66  ? -40.952 44.454  -88.549 1.00 25.47  ? 66  PHE C CG  1 
ATOM   7615  C  CD1 . PHE D 1 66  ? -41.075 43.528  -87.519 1.00 25.06  ? 66  PHE C CD1 1 
ATOM   7616  C  CD2 . PHE D 1 66  ? -41.074 44.011  -89.852 1.00 25.16  ? 66  PHE C CD2 1 
ATOM   7617  C  CE1 . PHE D 1 66  ? -41.326 42.192  -87.783 1.00 29.25  ? 66  PHE C CE1 1 
ATOM   7618  C  CE2 . PHE D 1 66  ? -41.330 42.671  -90.133 1.00 26.47  ? 66  PHE C CE2 1 
ATOM   7619  C  CZ  . PHE D 1 66  ? -41.454 41.759  -89.093 1.00 29.80  ? 66  PHE C CZ  1 
ATOM   7620  N  N   . LEU D 1 67  ? -42.057 48.612  -86.255 1.00 22.37  ? 67  LEU C N   1 
ATOM   7621  C  CA  . LEU D 1 67  ? -41.808 49.977  -85.800 1.00 24.67  ? 67  LEU C CA  1 
ATOM   7622  C  C   . LEU D 1 67  ? -40.481 49.999  -85.059 1.00 23.61  ? 67  LEU C C   1 
ATOM   7623  O  O   . LEU D 1 67  ? -40.350 49.379  -84.000 1.00 28.26  ? 67  LEU C O   1 
ATOM   7624  C  CB  . LEU D 1 67  ? -42.929 50.454  -84.882 1.00 24.68  ? 67  LEU C CB  1 
ATOM   7625  C  CG  . LEU D 1 67  ? -44.350 50.113  -85.312 1.00 26.67  ? 67  LEU C CG  1 
ATOM   7626  C  CD1 . LEU D 1 67  ? -45.325 50.501  -84.216 1.00 27.57  ? 67  LEU C CD1 1 
ATOM   7627  C  CD2 . LEU D 1 67  ? -44.685 50.819  -86.638 1.00 29.90  ? 67  LEU C CD2 1 
ATOM   7628  N  N   . VAL D 1 68  ? -39.488 50.675  -85.625 1.00 24.22  ? 68  VAL C N   1 
ATOM   7629  C  CA  . VAL D 1 68  ? -38.166 50.785  -85.016 1.00 27.04  ? 68  VAL C CA  1 
ATOM   7630  C  C   . VAL D 1 68  ? -37.897 52.240  -84.677 1.00 22.98  ? 68  VAL C C   1 
ATOM   7631  O  O   . VAL D 1 68  ? -38.120 53.130  -85.506 1.00 26.47  ? 68  VAL C O   1 
ATOM   7632  C  CB  . VAL D 1 68  ? -37.062 50.207  -85.918 1.00 24.45  ? 68  VAL C CB  1 
ATOM   7633  C  CG1 . VAL D 1 68  ? -35.693 50.435  -85.293 1.00 18.92  ? 68  VAL C CG1 1 
ATOM   7634  C  CG2 . VAL D 1 68  ? -37.301 48.713  -86.117 1.00 22.89  ? 68  VAL C CG2 1 
ATOM   7635  N  N   . GLN D 1 69  ? -37.381 52.472  -83.481 1.00 23.08  ? 69  GLN C N   1 
ATOM   7636  C  CA  . GLN D 1 69  ? -37.207 53.816  -82.955 1.00 29.17  ? 69  GLN C CA  1 
ATOM   7637  C  C   . GLN D 1 69  ? -35.824 53.912  -82.335 1.00 22.11  ? 69  GLN C C   1 
ATOM   7638  O  O   . GLN D 1 69  ? -35.531 53.215  -81.362 1.00 23.33  ? 69  GLN C O   1 
ATOM   7639  C  CB  . GLN D 1 69  ? -38.319 54.107  -81.950 1.00 32.67  ? 69  GLN C CB  1 
ATOM   7640  C  CG  . GLN D 1 69  ? -38.494 55.527  -81.523 1.00 35.79  ? 69  GLN C CG  1 
ATOM   7641  C  CD  . GLN D 1 69  ? -39.808 55.696  -80.791 1.00 39.61  ? 69  GLN C CD  1 
ATOM   7642  O  OE1 . GLN D 1 69  ? -40.803 55.031  -81.116 1.00 40.53  ? 69  GLN C OE1 1 
ATOM   7643  N  NE2 . GLN D 1 69  ? -39.818 56.553  -79.781 1.00 45.07  ? 69  GLN C NE2 1 
ATOM   7644  N  N   . ALA D 1 70  ? -34.961 54.739  -82.923 1.00 22.25  ? 70  ALA C N   1 
ATOM   7645  C  CA  . ALA D 1 70  ? -33.641 55.026  -82.368 1.00 25.38  ? 70  ALA C CA  1 
ATOM   7646  C  C   . ALA D 1 70  ? -33.740 56.322  -81.569 1.00 28.77  ? 70  ALA C C   1 
ATOM   7647  O  O   . ALA D 1 70  ? -33.817 57.410  -82.148 1.00 30.70  ? 70  ALA C O   1 
ATOM   7648  C  CB  . ALA D 1 70  ? -32.590 55.149  -83.469 1.00 23.66  ? 70  ALA C CB  1 
ATOM   7649  N  N   . GLY D 1 71  ? -33.716 56.212  -80.247 1.00 24.08  ? 71  GLY C N   1 
ATOM   7650  C  CA  . GLY D 1 71  ? -34.035 57.372  -79.446 1.00 31.99  ? 71  GLY C CA  1 
ATOM   7651  C  C   . GLY D 1 71  ? -35.421 57.866  -79.816 1.00 37.40  ? 71  GLY C C   1 
ATOM   7652  O  O   . GLY D 1 71  ? -36.417 57.168  -79.596 1.00 37.81  ? 71  GLY C O   1 
ATOM   7653  N  N   . ASN D 1 72  ? -35.485 59.062  -80.400 1.00 42.83  ? 72  ASN C N   1 
ATOM   7654  C  CA  . ASN D 1 72  ? -36.732 59.694  -80.813 1.00 40.55  ? 72  ASN C CA  1 
ATOM   7655  C  C   . ASN D 1 72  ? -36.964 59.685  -82.323 1.00 49.68  ? 72  ASN C C   1 
ATOM   7656  O  O   . ASN D 1 72  ? -37.996 60.202  -82.772 1.00 53.04  ? 72  ASN C O   1 
ATOM   7657  C  CB  . ASN D 1 72  ? -36.792 61.137  -80.304 1.00 45.15  ? 72  ASN C CB  1 
ATOM   7658  C  CG  . ASN D 1 72  ? -38.221 61.613  -80.072 1.00 61.07  ? 72  ASN C CG  1 
ATOM   7659  O  OD1 . ASN D 1 72  ? -38.838 61.298  -79.041 1.00 59.21  ? 72  ASN C OD1 1 
ATOM   7660  N  ND2 . ASN D 1 72  ? -38.758 62.384  -81.031 1.00 53.78  ? 72  ASN C ND2 1 
ATOM   7661  N  N   . VAL D 1 73  ? -36.032 59.166  -83.128 1.00 42.53  ? 73  VAL C N   1 
ATOM   7662  C  CA  . VAL D 1 73  ? -36.187 59.164  -84.581 1.00 42.13  ? 73  VAL C CA  1 
ATOM   7663  C  C   . VAL D 1 73  ? -36.702 57.799  -85.042 1.00 40.13  ? 73  VAL C C   1 
ATOM   7664  O  O   . VAL D 1 73  ? -36.192 56.745  -84.625 1.00 34.28  ? 73  VAL C O   1 
ATOM   7665  C  CB  . VAL D 1 73  ? -34.880 59.571  -85.292 1.00 38.52  ? 73  VAL C CB  1 
ATOM   7666  C  CG1 . VAL D 1 73  ? -33.730 58.763  -84.812 1.00 48.36  ? 73  VAL C CG1 1 
ATOM   7667  C  CG2 . VAL D 1 73  ? -35.015 59.385  -86.790 1.00 38.03  ? 73  VAL C CG2 1 
ATOM   7668  N  N   . GLN D 1 74  ? -37.743 57.827  -85.876 1.00 37.84  ? 74  GLN C N   1 
ATOM   7669  C  CA  . GLN D 1 74  ? -38.338 56.626  -86.451 1.00 33.07  ? 74  GLN C CA  1 
ATOM   7670  C  C   . GLN D 1 74  ? -37.493 56.183  -87.642 1.00 32.04  ? 74  GLN C C   1 
ATOM   7671  O  O   . GLN D 1 74  ? -37.181 56.990  -88.521 1.00 28.13  ? 74  GLN C O   1 
ATOM   7672  C  CB  . GLN D 1 74  ? -39.768 56.929  -86.903 1.00 33.26  ? 74  GLN C CB  1 
ATOM   7673  C  CG  . GLN D 1 74  ? -40.655 55.730  -87.153 1.00 37.20  ? 74  GLN C CG  1 
ATOM   7674  C  CD  . GLN D 1 74  ? -41.039 55.047  -85.858 1.00 36.29  ? 74  GLN C CD  1 
ATOM   7675  O  OE1 . GLN D 1 74  ? -41.165 55.697  -84.819 1.00 35.72  ? 74  GLN C OE1 1 
ATOM   7676  N  NE2 . GLN D 1 74  ? -41.198 53.732  -85.904 1.00 31.29  ? 74  GLN C NE2 1 
ATOM   7677  N  N   . LEU D 1 75  ? -37.099 54.918  -87.670 1.00 29.37  ? 75  LEU C N   1 
ATOM   7678  C  CA  . LEU D 1 75  ? -36.385 54.440  -88.845 1.00 26.70  ? 75  LEU C CA  1 
ATOM   7679  C  C   . LEU D 1 75  ? -37.350 53.791  -89.836 1.00 27.04  ? 75  LEU C C   1 
ATOM   7680  O  O   . LEU D 1 75  ? -38.442 53.331  -89.482 1.00 27.05  ? 75  LEU C O   1 
ATOM   7681  C  CB  . LEU D 1 75  ? -35.285 53.457  -88.460 1.00 23.90  ? 75  LEU C CB  1 
ATOM   7682  C  CG  . LEU D 1 75  ? -34.303 53.880  -87.373 1.00 24.90  ? 75  LEU C CG  1 
ATOM   7683  C  CD1 . LEU D 1 75  ? -33.166 52.870  -87.246 1.00 18.86  ? 75  LEU C CD1 1 
ATOM   7684  C  CD2 . LEU D 1 75  ? -33.778 55.282  -87.632 1.00 26.68  ? 75  LEU C CD2 1 
ATOM   7685  N  N   . ARG D 1 76  ? -36.919 53.739  -91.090 1.00 27.21  ? 76  ARG C N   1 
ATOM   7686  C  CA  . ARG D 1 76  ? -37.752 53.254  -92.183 1.00 29.56  ? 76  ARG C CA  1 
ATOM   7687  C  C   . ARG D 1 76  ? -37.263 51.868  -92.557 1.00 26.15  ? 76  ARG C C   1 
ATOM   7688  O  O   . ARG D 1 76  ? -36.128 51.712  -93.020 1.00 25.49  ? 76  ARG C O   1 
ATOM   7689  C  CB  . ARG D 1 76  ? -37.701 54.195  -93.397 1.00 26.50  ? 76  ARG C CB  1 
ATOM   7690  C  CG  . ARG D 1 76  ? -38.607 53.792  -94.564 1.00 21.89  ? 76  ARG C CG  1 
ATOM   7691  C  CD  . ARG D 1 76  ? -38.562 54.832  -95.685 1.00 30.33  ? 76  ARG C CD  1 
ATOM   7692  N  NE  . ARG D 1 76  ? -39.015 56.124  -95.177 1.00 26.35  ? 76  ARG C NE  1 
ATOM   7693  C  CZ  . ARG D 1 76  ? -40.272 56.543  -95.185 1.00 28.47  ? 76  ARG C CZ  1 
ATOM   7694  N  NH1 . ARG D 1 76  ? -41.246 55.818  -95.717 1.00 23.85  ? 76  ARG C NH1 1 
ATOM   7695  N  NH2 . ARG D 1 76  ? -40.570 57.698  -94.600 1.00 33.45  ? 76  ARG C NH2 1 
ATOM   7696  N  N   . VAL D 1 77  ? -38.133 50.879  -92.386 1.00 25.84  ? 77  VAL C N   1 
ATOM   7697  C  CA  . VAL D 1 77  ? -37.795 49.478  -92.595 1.00 23.51  ? 77  VAL C CA  1 
ATOM   7698  C  C   . VAL D 1 77  ? -38.061 49.144  -94.057 1.00 25.54  ? 77  VAL C C   1 
ATOM   7699  O  O   . VAL D 1 77  ? -39.195 49.268  -94.538 1.00 26.75  ? 77  VAL C O   1 
ATOM   7700  C  CB  . VAL D 1 77  ? -38.611 48.584  -91.653 1.00 29.24  ? 77  VAL C CB  1 
ATOM   7701  C  CG1 . VAL D 1 77  ? -38.341 47.084  -91.911 1.00 23.06  ? 77  VAL C CG1 1 
ATOM   7702  C  CG2 . VAL D 1 77  ? -38.346 48.976  -90.204 1.00 20.64  ? 77  VAL C CG2 1 
ATOM   7703  N  N   . ILE D 1 78  ? -37.015 48.726  -94.770 1.00 24.04  ? 78  ILE C N   1 
ATOM   7704  C  CA  . ILE D 1 78  ? -37.122 48.449  -96.192 1.00 20.41  ? 78  ILE C CA  1 
ATOM   7705  C  C   . ILE D 1 78  ? -36.931 46.983  -96.513 1.00 24.97  ? 78  ILE C C   1 
ATOM   7706  O  O   . ILE D 1 78  ? -37.031 46.611  -97.688 1.00 27.32  ? 78  ILE C O   1 
ATOM   7707  C  CB  . ILE D 1 78  ? -36.156 49.321  -97.019 1.00 23.14  ? 78  ILE C CB  1 
ATOM   7708  C  CG1 . ILE D 1 78  ? -34.700 49.037  -96.700 1.00 29.00  ? 78  ILE C CG1 1 
ATOM   7709  C  CG2 . ILE D 1 78  ? -36.386 50.806  -96.743 1.00 24.54  ? 78  ILE C CG2 1 
ATOM   7710  C  CD1 . ILE D 1 78  ? -33.750 49.901  -97.534 1.00 23.71  ? 78  ILE C CD1 1 
ATOM   7711  N  N   . GLY D 1 79  ? -36.707 46.129  -95.509 1.00 27.55  ? 79  GLY C N   1 
ATOM   7712  C  CA  . GLY D 1 79  ? -36.628 44.684  -95.706 1.00 19.78  ? 79  GLY C CA  1 
ATOM   7713  C  C   . GLY D 1 79  ? -36.600 43.964  -94.374 1.00 25.72  ? 79  GLY C C   1 
ATOM   7714  O  O   . GLY D 1 79  ? -36.336 44.564  -93.327 1.00 24.00  ? 79  GLY C O   1 
ATOM   7715  N  N   . HIS D 1 80  ? -36.913 42.667  -94.412 1.00 24.28  ? 80  HIS C N   1 
ATOM   7716  C  CA  . HIS D 1 80  ? -36.826 41.870  -93.189 1.00 27.55  ? 80  HIS C CA  1 
ATOM   7717  C  C   . HIS D 1 80  ? -36.543 40.418  -93.532 1.00 25.14  ? 80  HIS C C   1 
ATOM   7718  O  O   . HIS D 1 80  ? -36.915 39.933  -94.602 1.00 26.82  ? 80  HIS C O   1 
ATOM   7719  C  CB  . HIS D 1 80  ? -38.100 41.969  -92.330 1.00 28.40  ? 80  HIS C CB  1 
ATOM   7720  C  CG  . HIS D 1 80  ? -39.304 41.335  -92.954 1.00 32.66  ? 80  HIS C CG  1 
ATOM   7721  N  ND1 . HIS D 1 80  ? -40.176 42.029  -93.768 1.00 33.91  ? 80  HIS C ND1 1 
ATOM   7722  C  CD2 . HIS D 1 80  ? -39.765 40.061  -92.908 1.00 31.27  ? 80  HIS C CD2 1 
ATOM   7723  C  CE1 . HIS D 1 80  ? -41.135 41.215  -94.177 1.00 32.67  ? 80  HIS C CE1 1 
ATOM   7724  N  NE2 . HIS D 1 80  ? -40.907 40.014  -93.672 1.00 33.62  ? 80  HIS C NE2 1 
ATOM   7725  N  N   . SER D 1 81  ? -35.874 39.730  -92.611 1.00 29.66  ? 81  SER C N   1 
ATOM   7726  C  CA  . SER D 1 81  ? -35.628 38.297  -92.742 1.00 27.55  ? 81  SER C CA  1 
ATOM   7727  C  C   . SER D 1 81  ? -35.337 37.709  -91.365 1.00 34.47  ? 81  SER C C   1 
ATOM   7728  O  O   . SER D 1 81  ? -35.067 38.429  -90.395 1.00 28.25  ? 81  SER C O   1 
ATOM   7729  C  CB  . SER D 1 81  ? -34.479 38.004  -93.704 1.00 26.12  ? 81  SER C CB  1 
ATOM   7730  O  OG  . SER D 1 81  ? -33.304 38.663  -93.272 1.00 35.25  ? 81  SER C OG  1 
ATOM   7731  N  N   . MET D 1 82  ? -35.397 36.377  -91.301 1.00 34.11  ? 82  MET C N   1 
ATOM   7732  C  CA  . MET D 1 82  ? -35.194 35.611  -90.079 1.00 32.55  ? 82  MET C CA  1 
ATOM   7733  C  C   . MET D 1 82  ? -33.960 34.732  -90.235 1.00 32.32  ? 82  MET C C   1 
ATOM   7734  O  O   . MET D 1 82  ? -33.797 34.069  -91.260 1.00 39.77  ? 82  MET C O   1 
ATOM   7735  C  CB  . MET D 1 82  ? -36.432 34.769  -89.784 1.00 34.41  ? 82  MET C CB  1 
ATOM   7736  C  CG  . MET D 1 82  ? -36.355 33.961  -88.531 1.00 39.21  ? 82  MET C CG  1 
ATOM   7737  S  SD  . MET D 1 82  ? -37.994 33.401  -88.005 1.00 50.87  ? 82  MET C SD  1 
ATOM   7738  C  CE  . MET D 1 82  ? -38.444 32.298  -89.354 1.00 46.39  ? 82  MET C CE  1 
ATOM   7739  N  N   . GLN D 1 83  ? -33.080 34.748  -89.237 1.00 27.78  ? 83  GLN C N   1 
ATOM   7740  C  CA  . GLN D 1 83  ? -31.914 33.867  -89.184 1.00 32.37  ? 83  GLN C CA  1 
ATOM   7741  C  C   . GLN D 1 83  ? -31.901 33.187  -87.826 1.00 29.89  ? 83  GLN C C   1 
ATOM   7742  O  O   . GLN D 1 83  ? -31.607 33.829  -86.814 1.00 25.94  ? 83  GLN C O   1 
ATOM   7743  C  CB  . GLN D 1 83  ? -30.608 34.625  -89.410 1.00 30.02  ? 83  GLN C CB  1 
ATOM   7744  C  CG  . GLN D 1 83  ? -29.370 33.784  -89.122 1.00 29.30  ? 83  GLN C CG  1 
ATOM   7745  C  CD  . GLN D 1 83  ? -28.060 34.463  -89.534 1.00 35.02  ? 83  GLN C CD  1 
ATOM   7746  O  OE1 . GLN D 1 83  ? -27.981 35.697  -89.619 1.00 36.25  ? 83  GLN C OE1 1 
ATOM   7747  N  NE2 . GLN D 1 83  ? -27.015 33.652  -89.782 1.00 33.81  ? 83  GLN C NE2 1 
ATOM   7748  N  N   . ASN D 1 84  ? -32.208 31.890  -87.813 1.00 29.94  ? 84  ASN C N   1 
ATOM   7749  C  CA  . ASN D 1 84  ? -32.378 31.114  -86.588 1.00 24.92  ? 84  ASN C CA  1 
ATOM   7750  C  C   . ASN D 1 84  ? -33.331 31.869  -85.664 1.00 27.62  ? 84  ASN C C   1 
ATOM   7751  O  O   . ASN D 1 84  ? -34.500 32.066  -86.017 1.00 35.35  ? 84  ASN C O   1 
ATOM   7752  C  CB  . ASN D 1 84  ? -31.017 30.835  -85.957 1.00 18.57  ? 84  ASN C CB  1 
ATOM   7753  C  CG  . ASN D 1 84  ? -30.059 30.180  -86.945 1.00 22.24  ? 84  ASN C CG  1 
ATOM   7754  O  OD1 . ASN D 1 84  ? -28.957 30.681  -87.193 1.00 24.90  ? 84  ASN C OD1 1 
ATOM   7755  N  ND2 . ASN D 1 84  ? -30.502 29.094  -87.564 1.00 22.59  ? 84  ASN C ND2 1 
ATOM   7756  N  N   . CYS D 1 85  ? -32.870 32.315  -84.501 1.00 25.30  ? 85  CYS C N   1 
ATOM   7757  C  CA  . CYS D 1 85  ? -33.766 32.961  -83.557 1.00 30.11  ? 85  CYS C CA  1 
ATOM   7758  C  C   . CYS D 1 85  ? -33.694 34.488  -83.574 1.00 29.30  ? 85  CYS C C   1 
ATOM   7759  O  O   . CYS D 1 85  ? -34.325 35.118  -82.724 1.00 27.12  ? 85  CYS C O   1 
ATOM   7760  C  CB  . CYS D 1 85  ? -33.513 32.447  -82.141 1.00 27.33  ? 85  CYS C CB  1 
ATOM   7761  S  SG  . CYS D 1 85  ? -33.905 30.698  -81.923 1.00 28.40  ? 85  CYS C SG  1 
ATOM   7762  N  N   . VAL D 1 86  ? -32.980 35.108  -84.520 1.00 27.99  ? 86  VAL C N   1 
ATOM   7763  C  CA  . VAL D 1 86  ? -32.960 36.567  -84.584 1.00 27.05  ? 86  VAL C CA  1 
ATOM   7764  C  C   . VAL D 1 86  ? -33.671 37.051  -85.831 1.00 28.23  ? 86  VAL C C   1 
ATOM   7765  O  O   . VAL D 1 86  ? -33.650 36.414  -86.888 1.00 27.76  ? 86  VAL C O   1 
ATOM   7766  C  CB  . VAL D 1 86  ? -31.551 37.201  -84.547 1.00 33.24  ? 86  VAL C CB  1 
ATOM   7767  C  CG1 . VAL D 1 86  ? -30.867 36.938  -83.210 1.00 33.31  ? 86  VAL C CG1 1 
ATOM   7768  C  CG2 . VAL D 1 86  ? -30.718 36.772  -85.746 1.00 33.47  ? 86  VAL C CG2 1 
ATOM   7769  N  N   . LEU D 1 87  ? -34.306 38.205  -85.687 1.00 28.32  ? 87  LEU C N   1 
ATOM   7770  C  CA  . LEU D 1 87  ? -34.867 38.961  -86.794 1.00 26.51  ? 87  LEU C CA  1 
ATOM   7771  C  C   . LEU D 1 87  ? -33.864 40.020  -87.238 1.00 23.46  ? 87  LEU C C   1 
ATOM   7772  O  O   . LEU D 1 87  ? -33.211 40.652  -86.404 1.00 21.35  ? 87  LEU C O   1 
ATOM   7773  C  CB  . LEU D 1 87  ? -36.186 39.603  -86.370 1.00 26.61  ? 87  LEU C CB  1 
ATOM   7774  C  CG  . LEU D 1 87  ? -37.159 40.030  -87.463 1.00 29.96  ? 87  LEU C CG  1 
ATOM   7775  C  CD1 . LEU D 1 87  ? -37.652 38.837  -88.257 1.00 37.81  ? 87  LEU C CD1 1 
ATOM   7776  C  CD2 . LEU D 1 87  ? -38.319 40.708  -86.791 1.00 28.07  ? 87  LEU C CD2 1 
ATOM   7777  N  N   . LYS D 1 88  ? -33.736 40.203  -88.555 1.00 25.10  ? 88  LYS C N   1 
ATOM   7778  C  CA  . LYS D 1 88  ? -32.851 41.211  -89.151 1.00 26.16  ? 88  LYS C CA  1 
ATOM   7779  C  C   . LYS D 1 88  ? -33.696 42.171  -89.984 1.00 26.13  ? 88  LYS C C   1 
ATOM   7780  O  O   . LYS D 1 88  ? -34.255 41.781  -91.014 1.00 25.89  ? 88  LYS C O   1 
ATOM   7781  C  CB  . LYS D 1 88  ? -31.760 40.554  -89.994 1.00 22.18  ? 88  LYS C CB  1 
ATOM   7782  C  CG  . LYS D 1 88  ? -30.819 39.666  -89.179 1.00 29.20  ? 88  LYS C CG  1 
ATOM   7783  C  CD  . LYS D 1 88  ? -29.530 39.385  -89.925 1.00 25.55  ? 88  LYS C CD  1 
ATOM   7784  C  CE  . LYS D 1 88  ? -29.690 38.263  -90.939 1.00 24.04  ? 88  LYS C CE  1 
ATOM   7785  N  NZ  . LYS D 1 88  ? -28.362 37.803  -91.461 1.00 22.83  ? 88  LYS C NZ  1 
ATOM   7786  N  N   . LEU D 1 89  ? -33.795 43.420  -89.533 1.00 22.40  ? 89  LEU C N   1 
ATOM   7787  C  CA  . LEU D 1 89  ? -34.618 44.435  -90.180 1.00 20.21  ? 89  LEU C CA  1 
ATOM   7788  C  C   . LEU D 1 89  ? -33.671 45.386  -90.907 1.00 19.81  ? 89  LEU C C   1 
ATOM   7789  O  O   . LEU D 1 89  ? -32.916 46.124  -90.265 1.00 22.38  ? 89  LEU C O   1 
ATOM   7790  C  CB  . LEU D 1 89  ? -35.472 45.161  -89.139 1.00 18.63  ? 89  LEU C CB  1 
ATOM   7791  C  CG  . LEU D 1 89  ? -36.293 44.223  -88.225 1.00 26.46  ? 89  LEU C CG  1 
ATOM   7792  C  CD1 . LEU D 1 89  ? -37.095 44.964  -87.167 1.00 16.74  ? 89  LEU C CD1 1 
ATOM   7793  C  CD2 . LEU D 1 89  ? -37.231 43.320  -89.033 1.00 23.36  ? 89  LEU C CD2 1 
ATOM   7794  N  N   . LYS D 1 90  ? -33.698 45.366  -92.235 1.00 20.99  ? 90  LYS C N   1 
ATOM   7795  C  CA  . LYS D 1 90  ? -32.931 46.331  -93.015 1.00 22.04  ? 90  LYS C CA  1 
ATOM   7796  C  C   . LYS D 1 90  ? -33.637 47.685  -93.006 1.00 21.74  ? 90  LYS C C   1 
ATOM   7797  O  O   . LYS D 1 90  ? -34.836 47.766  -93.287 1.00 22.15  ? 90  LYS C O   1 
ATOM   7798  C  CB  . LYS D 1 90  ? -32.744 45.846  -94.447 1.00 23.44  ? 90  LYS C CB  1 
ATOM   7799  C  CG  . LYS D 1 90  ? -31.780 46.704  -95.242 1.00 28.42  ? 90  LYS C CG  1 
ATOM   7800  C  CD  . LYS D 1 90  ? -31.367 46.007  -96.531 1.00 39.44  ? 90  LYS C CD  1 
ATOM   7801  C  CE  . LYS D 1 90  ? -30.303 46.792  -97.284 1.00 34.46  ? 90  LYS C CE  1 
ATOM   7802  N  NZ  . LYS D 1 90  ? -30.899 47.929  -98.025 1.00 49.24  ? 90  LYS C NZ  1 
ATOM   7803  N  N   . VAL D 1 91  ? -32.899 48.736  -92.653 1.00 20.77  ? 91  VAL C N   1 
ATOM   7804  C  CA  . VAL D 1 91  ? -33.415 50.106  -92.621 1.00 28.80  ? 91  VAL C CA  1 
ATOM   7805  C  C   . VAL D 1 91  ? -32.701 50.926  -93.694 1.00 25.00  ? 91  VAL C C   1 
ATOM   7806  O  O   . VAL D 1 91  ? -31.629 50.560  -94.174 1.00 29.85  ? 91  VAL C O   1 
ATOM   7807  C  CB  . VAL D 1 91  ? -33.242 50.753  -91.226 1.00 22.23  ? 91  VAL C CB  1 
ATOM   7808  C  CG1 . VAL D 1 91  ? -34.104 50.053  -90.197 1.00 22.66  ? 91  VAL C CG1 1 
ATOM   7809  C  CG2 . VAL D 1 91  ? -31.801 50.697  -90.798 1.00 24.02  ? 91  VAL C CG2 1 
ATOM   7810  N  N   . ASP D 1 92  ? -33.297 52.050  -94.088 1.00 25.17  ? 92  ASP C N   1 
ATOM   7811  C  CA  . ASP D 1 92  ? -32.667 52.746  -95.215 1.00 35.64  ? 92  ASP C CA  1 
ATOM   7812  C  C   . ASP D 1 92  ? -31.507 53.652  -94.803 1.00 31.00  ? 92  ASP C C   1 
ATOM   7813  O  O   . ASP D 1 92  ? -30.863 54.236  -95.676 1.00 31.90  ? 92  ASP C O   1 
ATOM   7814  C  CB  . ASP D 1 92  ? -33.681 53.563  -96.028 1.00 29.70  ? 92  ASP C CB  1 
ATOM   7815  C  CG  . ASP D 1 92  ? -34.275 54.701  -95.247 1.00 34.91  ? 92  ASP C CG  1 
ATOM   7816  O  OD1 . ASP D 1 92  ? -34.040 54.741  -94.020 1.00 40.91  ? 92  ASP C OD1 1 
ATOM   7817  O  OD2 . ASP D 1 92  ? -34.918 55.590  -95.860 1.00 36.37  ? 92  ASP C OD2 1 
ATOM   7818  N  N   . THR D 1 93  ? -31.187 53.749  -93.519 1.00 31.45  ? 93  THR C N   1 
ATOM   7819  C  CA  . THR D 1 93  ? -30.161 54.659  -93.026 1.00 33.74  ? 93  THR C CA  1 
ATOM   7820  C  C   . THR D 1 93  ? -29.101 53.855  -92.294 1.00 31.13  ? 93  THR C C   1 
ATOM   7821  O  O   . THR D 1 93  ? -29.430 53.011  -91.453 1.00 28.65  ? 93  THR C O   1 
ATOM   7822  C  CB  . THR D 1 93  ? -30.760 55.724  -92.093 1.00 33.26  ? 93  THR C CB  1 
ATOM   7823  O  OG1 . THR D 1 93  ? -31.782 56.452  -92.783 1.00 35.15  ? 93  THR C OG1 1 
ATOM   7824  C  CG2 . THR D 1 93  ? -29.694 56.672  -91.591 1.00 33.49  ? 93  THR C CG2 1 
ATOM   7825  N  N   . ALA D 1 94  ? -27.837 54.080  -92.651 1.00 28.67  ? 94  ALA C N   1 
ATOM   7826  C  CA  . ALA D 1 94  ? -26.740 53.490  -91.897 1.00 29.08  ? 94  ALA C CA  1 
ATOM   7827  C  C   . ALA D 1 94  ? -26.603 54.207  -90.558 1.00 28.90  ? 94  ALA C C   1 
ATOM   7828  O  O   . ALA D 1 94  ? -26.655 55.439  -90.501 1.00 20.65  ? 94  ALA C O   1 
ATOM   7829  C  CB  . ALA D 1 94  ? -25.434 53.583  -92.682 1.00 22.36  ? 94  ALA C CB  1 
ATOM   7830  N  N   . ASN D 1 95  ? -26.459 53.429  -89.482 1.00 25.25  ? 95  ASN C N   1 
ATOM   7831  C  CA  . ASN D 1 95  ? -26.295 53.991  -88.156 1.00 24.40  ? 95  ASN C CA  1 
ATOM   7832  C  C   . ASN D 1 95  ? -24.972 54.739  -88.089 1.00 27.19  ? 95  ASN C C   1 
ATOM   7833  O  O   . ASN D 1 95  ? -23.916 54.093  -88.100 1.00 28.36  ? 95  ASN C O   1 
ATOM   7834  C  CB  . ASN D 1 95  ? -26.331 52.899  -87.096 1.00 24.49  ? 95  ASN C CB  1 
ATOM   7835  C  CG  . ASN D 1 95  ? -26.189 53.456  -85.697 1.00 25.96  ? 95  ASN C CG  1 
ATOM   7836  O  OD1 . ASN D 1 95  ? -26.149 54.665  -85.526 1.00 26.36  ? 95  ASN C OD1 1 
ATOM   7837  N  ND2 . ASN D 1 95  ? -26.060 52.582  -84.696 1.00 22.25  ? 95  ASN C ND2 1 
ATOM   7838  N  N   . PRO D 1 96  ? -24.967 56.072  -87.970 1.00 32.84  ? 96  PRO C N   1 
ATOM   7839  C  CA  . PRO D 1 96  ? -23.680 56.794  -87.946 1.00 29.20  ? 96  PRO C CA  1 
ATOM   7840  C  C   . PRO D 1 96  ? -22.811 56.449  -86.750 1.00 27.59  ? 96  PRO C C   1 
ATOM   7841  O  O   . PRO D 1 96  ? -21.584 56.595  -86.834 1.00 30.54  ? 96  PRO C O   1 
ATOM   7842  C  CB  . PRO D 1 96  ? -24.101 58.271  -87.935 1.00 23.12  ? 96  PRO C CB  1 
ATOM   7843  C  CG  . PRO D 1 96  ? -25.459 58.278  -87.366 1.00 27.01  ? 96  PRO C CG  1 
ATOM   7844  C  CD  . PRO D 1 96  ? -26.115 56.983  -87.799 1.00 29.14  ? 96  PRO C CD  1 
ATOM   7845  N  N   . LYS D 1 97  ? -23.387 55.933  -85.668 1.00 26.09  ? 97  LYS C N   1 
ATOM   7846  C  CA  . LYS D 1 97  ? -22.612 55.614  -84.482 1.00 25.09  ? 97  LYS C CA  1 
ATOM   7847  C  C   . LYS D 1 97  ? -22.111 54.183  -84.478 1.00 25.47  ? 97  LYS C C   1 
ATOM   7848  O  O   . LYS D 1 97  ? -21.670 53.701  -83.431 1.00 25.78  ? 97  LYS C O   1 
ATOM   7849  C  CB  . LYS D 1 97  ? -23.422 55.882  -83.211 1.00 33.83  ? 97  LYS C CB  1 
ATOM   7850  C  CG  . LYS D 1 97  ? -23.746 57.346  -82.924 1.00 33.42  ? 97  LYS C CG  1 
ATOM   7851  C  CD  . LYS D 1 97  ? -24.441 57.449  -81.574 1.00 36.15  ? 97  LYS C CD  1 
ATOM   7852  C  CE  . LYS D 1 97  ? -25.260 58.715  -81.442 1.00 42.21  ? 97  LYS C CE  1 
ATOM   7853  N  NZ  . LYS D 1 97  ? -26.137 58.654  -80.228 1.00 43.79  ? 97  LYS C NZ  1 
ATOM   7854  N  N   . THR D 1 98  ? -22.189 53.492  -85.616 1.00 26.92  ? 98  THR C N   1 
ATOM   7855  C  CA  . THR D 1 98  ? -21.713 52.123  -85.717 1.00 31.19  ? 98  THR C CA  1 
ATOM   7856  C  C   . THR D 1 98  ? -20.232 52.027  -85.370 1.00 25.94  ? 98  THR C C   1 
ATOM   7857  O  O   . THR D 1 98  ? -19.406 52.692  -86.019 1.00 32.69  ? 98  THR C O   1 
ATOM   7858  C  CB  . THR D 1 98  ? -21.933 51.559  -87.120 1.00 30.54  ? 98  THR C CB  1 
ATOM   7859  O  OG1 . THR D 1 98  ? -23.321 51.626  -87.445 1.00 23.65  ? 98  THR C OG1 1 
ATOM   7860  C  CG2 . THR D 1 98  ? -21.468 50.099  -87.155 1.00 25.39  ? 98  THR C CG2 1 
ATOM   7861  N  N   . PRO D 1 99  ? -19.854 51.222  -84.383 1.00 24.46  ? 99  PRO C N   1 
ATOM   7862  C  CA  . PRO D 1 99  ? -18.436 50.987  -84.104 1.00 22.19  ? 99  PRO C CA  1 
ATOM   7863  C  C   . PRO D 1 99  ? -17.880 49.913  -85.025 1.00 24.63  ? 99  PRO C C   1 
ATOM   7864  O  O   . PRO D 1 99  ? -18.622 49.203  -85.709 1.00 29.27  ? 99  PRO C O   1 
ATOM   7865  C  CB  . PRO D 1 99  ? -18.454 50.502  -82.653 1.00 26.56  ? 99  PRO C CB  1 
ATOM   7866  C  CG  . PRO D 1 99  ? -19.749 49.710  -82.573 1.00 25.37  ? 99  PRO C CG  1 
ATOM   7867  C  CD  . PRO D 1 99  ? -20.732 50.452  -83.484 1.00 25.48  ? 99  PRO C CD  1 
ATOM   7868  N  N   . LYS D 1 100 ? -16.553 49.781  -85.021 1.00 23.48  ? 100 LYS C N   1 
ATOM   7869  C  CA  . LYS D 1 100 ? -15.956 48.552  -85.530 1.00 27.03  ? 100 LYS C CA  1 
ATOM   7870  C  C   . LYS D 1 100 ? -16.472 47.393  -84.682 1.00 25.15  ? 100 LYS C C   1 
ATOM   7871  O  O   . LYS D 1 100 ? -16.521 47.491  -83.454 1.00 25.56  ? 100 LYS C O   1 
ATOM   7872  C  CB  . LYS D 1 100 ? -14.437 48.599  -85.443 1.00 31.38  ? 100 LYS C CB  1 
ATOM   7873  C  CG  . LYS D 1 100 ? -13.786 49.889  -85.832 1.00 39.88  ? 100 LYS C CG  1 
ATOM   7874  C  CD  . LYS D 1 100 ? -12.279 49.691  -85.737 1.00 42.45  ? 100 LYS C CD  1 
ATOM   7875  C  CE  . LYS D 1 100 ? -11.498 50.881  -86.205 1.00 50.27  ? 100 LYS C CE  1 
ATOM   7876  N  NZ  . LYS D 1 100 ? -10.043 50.517  -86.190 1.00 58.20  ? 100 LYS C NZ  1 
ATOM   7877  N  N   . TYR D 1 101 ? -16.896 46.314  -85.324 1.00 22.05  ? 101 TYR C N   1 
ATOM   7878  C  CA  . TYR D 1 101 ? -17.569 45.280  -84.554 1.00 27.89  ? 101 TYR C CA  1 
ATOM   7879  C  C   . TYR D 1 101 ? -17.413 43.931  -85.227 1.00 25.13  ? 101 TYR C C   1 
ATOM   7880  O  O   . TYR D 1 101 ? -17.166 43.837  -86.433 1.00 25.97  ? 101 TYR C O   1 
ATOM   7881  C  CB  . TYR D 1 101 ? -19.062 45.581  -84.363 1.00 24.66  ? 101 TYR C CB  1 
ATOM   7882  C  CG  . TYR D 1 101 ? -19.922 45.376  -85.603 1.00 27.61  ? 101 TYR C CG  1 
ATOM   7883  C  CD1 . TYR D 1 101 ? -20.511 44.132  -85.886 1.00 24.29  ? 101 TYR C CD1 1 
ATOM   7884  C  CD2 . TYR D 1 101 ? -20.167 46.431  -86.474 1.00 23.23  ? 101 TYR C CD2 1 
ATOM   7885  C  CE1 . TYR D 1 101 ? -21.303 43.956  -87.013 1.00 23.68  ? 101 TYR C CE1 1 
ATOM   7886  C  CE2 . TYR D 1 101 ? -20.960 46.268  -87.594 1.00 25.06  ? 101 TYR C CE2 1 
ATOM   7887  C  CZ  . TYR D 1 101 ? -21.521 45.032  -87.861 1.00 32.67  ? 101 TYR C CZ  1 
ATOM   7888  O  OH  . TYR D 1 101 ? -22.305 44.902  -88.986 1.00 37.76  ? 101 TYR C OH  1 
ATOM   7889  N  N   . LYS D 1 102 ? -17.556 42.887  -84.411 1.00 26.11  ? 102 LYS C N   1 
ATOM   7890  C  CA  . LYS D 1 102 ? -17.659 41.512  -84.866 1.00 27.20  ? 102 LYS C CA  1 
ATOM   7891  C  C   . LYS D 1 102 ? -18.745 40.806  -84.073 1.00 29.75  ? 102 LYS C C   1 
ATOM   7892  O  O   . LYS D 1 102 ? -19.141 41.241  -82.987 1.00 30.26  ? 102 LYS C O   1 
ATOM   7893  C  CB  . LYS D 1 102 ? -16.358 40.718  -84.704 1.00 32.90  ? 102 LYS C CB  1 
ATOM   7894  C  CG  . LYS D 1 102 ? -15.160 41.266  -85.415 1.00 41.01  ? 102 LYS C CG  1 
ATOM   7895  C  CD  . LYS D 1 102 ? -13.896 41.034  -84.587 1.00 50.72  ? 102 LYS C CD  1 
ATOM   7896  C  CE  . LYS D 1 102 ? -13.980 39.751  -83.760 1.00 45.80  ? 102 LYS C CE  1 
ATOM   7897  N  NZ  . LYS D 1 102 ? -12.883 39.674  -82.744 1.00 43.96  ? 102 LYS C NZ  1 
ATOM   7898  N  N   . PHE D 1 103 ? -19.223 39.709  -84.646 1.00 31.39  ? 103 PHE C N   1 
ATOM   7899  C  CA  . PHE D 1 103 ? -20.047 38.722  -83.954 1.00 31.25  ? 103 PHE C CA  1 
ATOM   7900  C  C   . PHE D 1 103 ? -19.153 37.539  -83.614 1.00 26.43  ? 103 PHE C C   1 
ATOM   7901  O  O   . PHE D 1 103 ? -18.456 37.025  -84.494 1.00 24.01  ? 103 PHE C O   1 
ATOM   7902  C  CB  . PHE D 1 103 ? -21.214 38.255  -84.827 1.00 24.13  ? 103 PHE C CB  1 
ATOM   7903  C  CG  . PHE D 1 103 ? -22.214 39.329  -85.127 1.00 24.45  ? 103 PHE C CG  1 
ATOM   7904  C  CD1 . PHE D 1 103 ? -22.183 40.542  -84.453 1.00 24.43  ? 103 PHE C CD1 1 
ATOM   7905  C  CD2 . PHE D 1 103 ? -23.195 39.130  -86.073 1.00 23.00  ? 103 PHE C CD2 1 
ATOM   7906  C  CE1 . PHE D 1 103 ? -23.101 41.521  -84.734 1.00 20.83  ? 103 PHE C CE1 1 
ATOM   7907  C  CE2 . PHE D 1 103 ? -24.125 40.116  -86.341 1.00 19.55  ? 103 PHE C CE2 1 
ATOM   7908  C  CZ  . PHE D 1 103 ? -24.076 41.296  -85.673 1.00 19.49  ? 103 PHE C CZ  1 
ATOM   7909  N  N   . VAL D 1 104 ? -19.120 37.158  -82.335 1.00 24.96  ? 104 VAL C N   1 
ATOM   7910  C  CA  . VAL D 1 104 ? -18.367 35.994  -81.881 1.00 29.30  ? 104 VAL C CA  1 
ATOM   7911  C  C   . VAL D 1 104 ? -19.270 35.105  -81.039 1.00 23.85  ? 104 VAL C C   1 
ATOM   7912  O  O   . VAL D 1 104 ? -20.267 35.549  -80.470 1.00 26.74  ? 104 VAL C O   1 
ATOM   7913  C  CB  . VAL D 1 104 ? -17.118 36.366  -81.066 1.00 28.24  ? 104 VAL C CB  1 
ATOM   7914  C  CG1 . VAL D 1 104 ? -16.163 37.210  -81.887 1.00 34.68  ? 104 VAL C CG1 1 
ATOM   7915  C  CG2 . VAL D 1 104 ? -17.559 37.128  -79.843 1.00 35.81  ? 104 VAL C CG2 1 
ATOM   7916  N  N   . ARG D 1 105 ? -18.916 33.830  -80.979 1.00 21.46  ? 105 ARG C N   1 
ATOM   7917  C  CA  . ARG D 1 105 ? -19.581 32.881  -80.094 1.00 27.96  ? 105 ARG C CA  1 
ATOM   7918  C  C   . ARG D 1 105 ? -18.615 32.568  -78.959 1.00 28.91  ? 105 ARG C C   1 
ATOM   7919  O  O   . ARG D 1 105 ? -17.549 31.991  -79.195 1.00 31.22  ? 105 ARG C O   1 
ATOM   7920  C  CB  . ARG D 1 105 ? -19.994 31.619  -80.845 1.00 25.18  ? 105 ARG C CB  1 
ATOM   7921  C  CG  . ARG D 1 105 ? -20.922 30.754  -80.058 1.00 26.22  ? 105 ARG C CG  1 
ATOM   7922  C  CD  . ARG D 1 105 ? -21.842 29.961  -80.935 1.00 24.87  ? 105 ARG C CD  1 
ATOM   7923  N  NE  . ARG D 1 105 ? -22.627 29.042  -80.123 1.00 32.89  ? 105 ARG C NE  1 
ATOM   7924  C  CZ  . ARG D 1 105 ? -23.886 29.249  -79.752 1.00 32.80  ? 105 ARG C CZ  1 
ATOM   7925  N  NH1 . ARG D 1 105 ? -24.554 30.328  -80.138 1.00 28.69  ? 105 ARG C NH1 1 
ATOM   7926  N  NH2 . ARG D 1 105 ? -24.489 28.349  -78.974 1.00 29.03  ? 105 ARG C NH2 1 
ATOM   7927  N  N   . ILE D 1 106 ? -18.977 32.960  -77.733 1.00 22.97  ? 106 ILE C N   1 
ATOM   7928  C  CA  . ILE D 1 106 ? -18.106 32.723  -76.594 1.00 25.26  ? 106 ILE C CA  1 
ATOM   7929  C  C   . ILE D 1 106 ? -18.272 31.295  -76.110 1.00 30.79  ? 106 ILE C C   1 
ATOM   7930  O  O   . ILE D 1 106 ? -19.316 30.667  -76.280 1.00 29.62  ? 106 ILE C O   1 
ATOM   7931  C  CB  . ILE D 1 106 ? -18.380 33.698  -75.441 1.00 27.77  ? 106 ILE C CB  1 
ATOM   7932  C  CG1 . ILE D 1 106 ? -19.867 33.731  -75.151 1.00 24.70  ? 106 ILE C CG1 1 
ATOM   7933  C  CG2 . ILE D 1 106 ? -17.775 35.060  -75.677 1.00 32.75  ? 106 ILE C CG2 1 
ATOM   7934  C  CD1 . ILE D 1 106 ? -20.130 34.359  -73.889 1.00 30.37  ? 106 ILE C CD1 1 
ATOM   7935  N  N   . GLN D 1 107 ? -17.299 30.844  -75.454 1.00 34.74  ? 107 GLN C N   1 
ATOM   7936  C  CA  . GLN D 1 107 ? -17.098 29.558  -74.833 1.00 33.48  ? 107 GLN C CA  1 
ATOM   7937  C  C   . GLN D 1 107 ? -17.450 29.639  -73.354 1.00 35.37  ? 107 GLN C C   1 
ATOM   7938  O  O   . GLN D 1 107 ? -17.270 30.694  -72.732 1.00 29.54  ? 107 GLN C O   1 
ATOM   7939  C  CB  . GLN D 1 107 ? -15.631 29.149  -74.988 1.00 32.84  ? 107 GLN C CB  1 
ATOM   7940  C  CG  . GLN D 1 107 ? -15.218 28.974  -76.451 1.00 40.28  ? 107 GLN C CG  1 
ATOM   7941  C  CD  . GLN D 1 107 ? -16.031 27.913  -77.184 1.00 46.11  ? 107 GLN C CD  1 
ATOM   7942  O  OE1 . GLN D 1 107 ? -16.077 26.741  -76.779 1.00 54.28  ? 107 GLN C OE1 1 
ATOM   7943  N  NE2 . GLN D 1 107 ? -16.700 28.328  -78.258 1.00 52.21  ? 107 GLN C NE2 1 
ATOM   7944  N  N   . PRO D 1 108 ? -17.949 28.529  -72.758 1.00 35.67  ? 108 PRO C N   1 
ATOM   7945  C  CA  . PRO D 1 108 ? -18.221 28.493  -71.324 1.00 30.20  ? 108 PRO C CA  1 
ATOM   7946  C  C   . PRO D 1 108 ? -17.000 28.894  -70.482 1.00 28.69  ? 108 PRO C C   1 
ATOM   7947  O  O   . PRO D 1 108 ? -15.925 28.481  -70.793 1.00 27.56  ? 108 PRO C O   1 
ATOM   7948  C  CB  . PRO D 1 108 ? -18.651 27.038  -71.099 1.00 29.55  ? 108 PRO C CB  1 
ATOM   7949  C  CG  . PRO D 1 108 ? -19.262 26.637  -72.404 1.00 29.83  ? 108 PRO C CG  1 
ATOM   7950  C  CD  . PRO D 1 108 ? -18.327 27.262  -73.410 1.00 24.66  ? 108 PRO C CD  1 
ATOM   7951  N  N   . GLY D 1 109 ? -17.219 29.710  -69.452 1.00 26.67  ? 109 GLY C N   1 
ATOM   7952  C  CA  . GLY D 1 109 ? -16.128 30.200  -68.636 1.00 27.58  ? 109 GLY C CA  1 
ATOM   7953  C  C   . GLY D 1 109 ? -15.570 31.559  -69.030 1.00 26.98  ? 109 GLY C C   1 
ATOM   7954  O  O   . GLY D 1 109 ? -14.792 32.136  -68.256 1.00 23.82  ? 109 GLY C O   1 
ATOM   7955  N  N   . GLN D 1 110 ? -15.935 32.078  -70.205 1.00 27.71  ? 110 GLN C N   1 
ATOM   7956  C  CA  . GLN D 1 110 ? -15.554 33.412  -70.653 1.00 30.22  ? 110 GLN C CA  1 
ATOM   7957  C  C   . GLN D 1 110 ? -16.561 34.443  -70.140 1.00 31.49  ? 110 GLN C C   1 
ATOM   7958  O  O   . GLN D 1 110 ? -17.700 34.119  -69.791 1.00 29.17  ? 110 GLN C O   1 
ATOM   7959  C  CB  . GLN D 1 110 ? -15.472 33.487  -72.179 1.00 25.11  ? 110 GLN C CB  1 
ATOM   7960  C  CG  . GLN D 1 110 ? -14.423 32.615  -72.835 1.00 27.72  ? 110 GLN C CG  1 
ATOM   7961  C  CD  . GLN D 1 110 ? -14.347 32.853  -74.349 1.00 46.82  ? 110 GLN C CD  1 
ATOM   7962  O  OE1 . GLN D 1 110 ? -14.955 32.124  -75.145 1.00 40.50  ? 110 GLN C OE1 1 
ATOM   7963  N  NE2 . GLN D 1 110 ? -13.604 33.896  -74.752 1.00 43.92  ? 110 GLN C NE2 1 
ATOM   7964  N  N   . THR D 1 111 ? -16.123 35.697  -70.086 1.00 27.58  ? 111 THR C N   1 
ATOM   7965  C  CA  . THR D 1 111 ? -16.927 36.761  -69.510 1.00 27.45  ? 111 THR C CA  1 
ATOM   7966  C  C   . THR D 1 111 ? -17.233 37.815  -70.566 1.00 30.30  ? 111 THR C C   1 
ATOM   7967  O  O   . THR D 1 111 ? -16.610 37.870  -71.640 1.00 26.76  ? 111 THR C O   1 
ATOM   7968  C  CB  . THR D 1 111 ? -16.216 37.415  -68.320 1.00 29.25  ? 111 THR C CB  1 
ATOM   7969  O  OG1 . THR D 1 111 ? -14.940 37.931  -68.743 1.00 30.14  ? 111 THR C OG1 1 
ATOM   7970  C  CG2 . THR D 1 111 ? -16.018 36.380  -67.196 1.00 26.73  ? 111 THR C CG2 1 
ATOM   7971  N  N   . PHE D 1 112 ? -18.199 38.667  -70.227 1.00 22.36  ? 112 PHE C N   1 
ATOM   7972  C  CA  . PHE D 1 112 ? -18.604 39.774  -71.069 1.00 21.48  ? 112 PHE C CA  1 
ATOM   7973  C  C   . PHE D 1 112 ? -19.470 40.716  -70.245 1.00 23.84  ? 112 PHE C C   1 
ATOM   7974  O  O   . PHE D 1 112 ? -19.992 40.344  -69.191 1.00 21.68  ? 112 PHE C O   1 
ATOM   7975  C  CB  . PHE D 1 112 ? -19.361 39.282  -72.304 1.00 20.75  ? 112 PHE C CB  1 
ATOM   7976  C  CG  . PHE D 1 112 ? -20.578 38.439  -71.982 1.00 24.89  ? 112 PHE C CG  1 
ATOM   7977  C  CD1 . PHE D 1 112 ? -21.819 39.026  -71.789 1.00 23.58  ? 112 PHE C CD1 1 
ATOM   7978  C  CD2 . PHE D 1 112 ? -20.484 37.063  -71.898 1.00 23.91  ? 112 PHE C CD2 1 
ATOM   7979  C  CE1 . PHE D 1 112 ? -22.924 38.266  -71.515 1.00 22.74  ? 112 PHE C CE1 1 
ATOM   7980  C  CE2 . PHE D 1 112 ? -21.596 36.289  -71.625 1.00 27.58  ? 112 PHE C CE2 1 
ATOM   7981  C  CZ  . PHE D 1 112 ? -22.809 36.881  -71.426 1.00 26.14  ? 112 PHE C CZ  1 
ATOM   7982  N  N   . SER D 1 113 ? -19.633 41.937  -70.760 1.00 23.15  ? 113 SER C N   1 
ATOM   7983  C  CA  . SER D 1 113 ? -20.501 42.939  -70.156 1.00 25.16  ? 113 SER C CA  1 
ATOM   7984  C  C   . SER D 1 113 ? -21.868 42.898  -70.808 1.00 20.60  ? 113 SER C C   1 
ATOM   7985  O  O   . SER D 1 113 ? -22.000 42.581  -71.993 1.00 18.79  ? 113 SER C O   1 
ATOM   7986  C  CB  . SER D 1 113 ? -19.934 44.351  -70.311 1.00 20.07  ? 113 SER C CB  1 
ATOM   7987  O  OG  . SER D 1 113 ? -18.602 44.402  -69.882 1.00 20.11  ? 113 SER C OG  1 
ATOM   7988  N  N   . VAL D 1 114 ? -22.881 43.220  -70.011 1.00 20.05  ? 114 VAL C N   1 
ATOM   7989  C  CA  . VAL D 1 114 ? -24.263 43.294  -70.452 1.00 17.25  ? 114 VAL C CA  1 
ATOM   7990  C  C   . VAL D 1 114 ? -24.702 44.733  -70.256 1.00 20.50  ? 114 VAL C C   1 
ATOM   7991  O  O   . VAL D 1 114 ? -24.582 45.280  -69.151 1.00 20.44  ? 114 VAL C O   1 
ATOM   7992  C  CB  . VAL D 1 114 ? -25.176 42.330  -69.670 1.00 21.91  ? 114 VAL C CB  1 
ATOM   7993  C  CG1 . VAL D 1 114 ? -26.632 42.486  -70.099 1.00 19.47  ? 114 VAL C CG1 1 
ATOM   7994  C  CG2 . VAL D 1 114 ? -24.724 40.887  -69.822 1.00 20.82  ? 114 VAL C CG2 1 
ATOM   7995  N  N   . LEU D 1 115 ? -25.193 45.346  -71.326 1.00 21.35  ? 115 LEU C N   1 
ATOM   7996  C  CA  . LEU D 1 115 ? -25.849 46.650  -71.281 1.00 17.21  ? 115 LEU C CA  1 
ATOM   7997  C  C   . LEU D 1 115 ? -27.340 46.378  -71.256 1.00 19.81  ? 115 LEU C C   1 
ATOM   7998  O  O   . LEU D 1 115 ? -27.949 46.107  -72.295 1.00 21.35  ? 115 LEU C O   1 
ATOM   7999  C  CB  . LEU D 1 115 ? -25.467 47.509  -72.477 1.00 15.90  ? 115 LEU C CB  1 
ATOM   8000  C  CG  . LEU D 1 115 ? -26.221 48.831  -72.474 1.00 21.25  ? 115 LEU C CG  1 
ATOM   8001  C  CD1 . LEU D 1 115 ? -25.731 49.698  -71.329 1.00 19.68  ? 115 LEU C CD1 1 
ATOM   8002  C  CD2 . LEU D 1 115 ? -26.082 49.554  -73.831 1.00 22.32  ? 115 LEU C CD2 1 
ATOM   8003  N  N   . ALA D 1 116 ? -27.918 46.424  -70.058 1.00 23.93  ? 116 ALA C N   1 
ATOM   8004  C  CA  . ALA D 1 116 ? -29.323 46.094  -69.868 1.00 23.19  ? 116 ALA C CA  1 
ATOM   8005  C  C   . ALA D 1 116 ? -30.193 47.231  -70.367 1.00 20.50  ? 116 ALA C C   1 
ATOM   8006  O  O   . ALA D 1 116 ? -30.006 48.381  -69.964 1.00 25.76  ? 116 ALA C O   1 
ATOM   8007  C  CB  . ALA D 1 116 ? -29.598 45.826  -68.395 1.00 21.42  ? 116 ALA C CB  1 
ATOM   8008  N  N   . CYS D 1 117 ? -31.140 46.916  -71.245 1.00 21.48  ? 117 CYS C N   1 
ATOM   8009  C  CA  . CYS D 1 117 ? -31.944 47.940  -71.886 1.00 26.69  ? 117 CYS C CA  1 
ATOM   8010  C  C   . CYS D 1 117 ? -33.433 47.674  -71.737 1.00 27.52  ? 117 CYS C C   1 
ATOM   8011  O  O   . CYS D 1 117 ? -33.875 46.535  -71.562 1.00 27.89  ? 117 CYS C O   1 
ATOM   8012  C  CB  . CYS D 1 117 ? -31.602 48.071  -73.367 1.00 33.99  ? 117 CYS C CB  1 
ATOM   8013  S  SG  . CYS D 1 117 ? -29.980 48.752  -73.732 1.00 30.96  ? 117 CYS C SG  1 
ATOM   8014  N  N   . TYR D 1 118 ? -34.200 48.764  -71.790 1.00 28.64  ? 118 TYR C N   1 
ATOM   8015  C  CA  . TYR D 1 118 ? -35.659 48.736  -71.807 1.00 27.37  ? 118 TYR C CA  1 
ATOM   8016  C  C   . TYR D 1 118 ? -36.117 49.847  -72.744 1.00 28.81  ? 118 TYR C C   1 
ATOM   8017  O  O   . TYR D 1 118 ? -35.647 50.985  -72.628 1.00 27.61  ? 118 TYR C O   1 
ATOM   8018  C  CB  . TYR D 1 118 ? -36.241 48.917  -70.391 1.00 24.38  ? 118 TYR C CB  1 
ATOM   8019  C  CG  . TYR D 1 118 ? -35.727 47.854  -69.451 1.00 33.82  ? 118 TYR C CG  1 
ATOM   8020  C  CD1 . TYR D 1 118 ? -36.350 46.611  -69.355 1.00 27.63  ? 118 TYR C CD1 1 
ATOM   8021  C  CD2 . TYR D 1 118 ? -34.576 48.065  -68.706 1.00 32.77  ? 118 TYR C CD2 1 
ATOM   8022  C  CE1 . TYR D 1 118 ? -35.845 45.627  -68.526 1.00 28.12  ? 118 TYR C CE1 1 
ATOM   8023  C  CE2 . TYR D 1 118 ? -34.072 47.095  -67.874 1.00 24.36  ? 118 TYR C CE2 1 
ATOM   8024  C  CZ  . TYR D 1 118 ? -34.701 45.880  -67.787 1.00 28.20  ? 118 TYR C CZ  1 
ATOM   8025  O  OH  . TYR D 1 118 ? -34.172 44.915  -66.957 1.00 21.76  ? 118 TYR C OH  1 
ATOM   8026  N  N   . ASN D 1 119 ? -36.978 49.489  -73.706 1.00 28.24  ? 119 ASN C N   1 
ATOM   8027  C  CA  . ASN D 1 119 ? -37.540 50.426  -74.687 1.00 34.22  ? 119 ASN C CA  1 
ATOM   8028  C  C   . ASN D 1 119 ? -36.453 51.129  -75.493 1.00 28.51  ? 119 ASN C C   1 
ATOM   8029  O  O   . ASN D 1 119 ? -36.560 52.310  -75.806 1.00 33.28  ? 119 ASN C O   1 
ATOM   8030  C  CB  . ASN D 1 119 ? -38.450 51.455  -74.009 1.00 31.30  ? 119 ASN C CB  1 
ATOM   8031  C  CG  . ASN D 1 119 ? -39.377 50.820  -73.001 1.00 33.97  ? 119 ASN C CG  1 
ATOM   8032  O  OD1 . ASN D 1 119 ? -40.277 50.062  -73.361 1.00 35.04  ? 119 ASN C OD1 1 
ATOM   8033  N  ND2 . ASN D 1 119 ? -39.166 51.125  -71.730 1.00 33.84  ? 119 ASN C ND2 1 
ATOM   8034  N  N   . GLY D 1 120 ? -35.403 50.400  -75.846 1.00 29.12  ? 120 GLY C N   1 
ATOM   8035  C  CA  . GLY D 1 120 ? -34.330 50.996  -76.611 1.00 21.86  ? 120 GLY C CA  1 
ATOM   8036  C  C   . GLY D 1 120 ? -33.468 52.003  -75.887 1.00 24.11  ? 120 GLY C C   1 
ATOM   8037  O  O   . GLY D 1 120 ? -32.727 52.729  -76.550 1.00 30.21  ? 120 GLY C O   1 
ATOM   8038  N  N   . SER D 1 121 ? -33.535 52.096  -74.554 1.00 27.52  ? 121 SER C N   1 
ATOM   8039  C  CA  . SER D 1 121 ? -32.539 52.942  -73.901 1.00 29.87  ? 121 SER C CA  1 
ATOM   8040  C  C   . SER D 1 121 ? -31.845 52.214  -72.756 1.00 32.52  ? 121 SER C C   1 
ATOM   8041  O  O   . SER D 1 121 ? -32.457 51.406  -72.038 1.00 27.34  ? 121 SER C O   1 
ATOM   8042  C  CB  . SER D 1 121 ? -33.126 54.273  -73.390 1.00 30.70  ? 121 SER C CB  1 
ATOM   8043  O  OG  . SER D 1 121 ? -34.324 54.117  -72.688 1.00 29.52  ? 121 SER C OG  1 
ATOM   8044  N  N   . PRO D 1 122 ? -30.557 52.488  -72.565 1.00 32.78  ? 122 PRO C N   1 
ATOM   8045  C  CA  . PRO D 1 122 ? -29.765 51.691  -71.623 1.00 29.83  ? 122 PRO C CA  1 
ATOM   8046  C  C   . PRO D 1 122 ? -30.093 52.011  -70.176 1.00 36.46  ? 122 PRO C C   1 
ATOM   8047  O  O   . PRO D 1 122 ? -30.304 53.166  -69.797 1.00 37.03  ? 122 PRO C O   1 
ATOM   8048  C  CB  . PRO D 1 122 ? -28.325 52.077  -71.970 1.00 28.61  ? 122 PRO C CB  1 
ATOM   8049  C  CG  . PRO D 1 122 ? -28.402 52.465  -73.448 1.00 29.93  ? 122 PRO C CG  1 
ATOM   8050  C  CD  . PRO D 1 122 ? -29.702 53.225  -73.517 1.00 33.73  ? 122 PRO C CD  1 
ATOM   8051  N  N   . SER D 1 123 ? -30.096 50.963  -69.361 1.00 36.84  ? 123 SER C N   1 
ATOM   8052  C  CA  . SER D 1 123 ? -30.398 51.047  -67.943 1.00 35.51  ? 123 SER C CA  1 
ATOM   8053  C  C   . SER D 1 123 ? -29.178 50.870  -67.058 1.00 34.19  ? 123 SER C C   1 
ATOM   8054  O  O   . SER D 1 123 ? -29.060 51.547  -66.037 1.00 30.70  ? 123 SER C O   1 
ATOM   8055  C  CB  . SER D 1 123 ? -31.439 49.992  -67.577 1.00 32.40  ? 123 SER C CB  1 
ATOM   8056  O  OG  . SER D 1 123 ? -31.726 50.060  -66.199 1.00 44.54  ? 123 SER C OG  1 
ATOM   8057  N  N   . GLY D 1 124 ? -28.276 49.968  -67.423 1.00 24.56  ? 124 GLY C N   1 
ATOM   8058  C  CA  . GLY D 1 124 ? -27.117 49.691  -66.603 1.00 22.25  ? 124 GLY C CA  1 
ATOM   8059  C  C   . GLY D 1 124 ? -26.204 48.732  -67.322 1.00 23.83  ? 124 GLY C C   1 
ATOM   8060  O  O   . GLY D 1 124 ? -26.556 48.146  -68.352 1.00 20.21  ? 124 GLY C O   1 
ATOM   8061  N  N   . VAL D 1 125 ? -24.998 48.624  -66.793 1.00 18.39  ? 125 VAL C N   1 
ATOM   8062  C  CA  . VAL D 1 125 ? -23.973 47.767  -67.355 1.00 19.51  ? 125 VAL C CA  1 
ATOM   8063  C  C   . VAL D 1 125 ? -23.376 46.948  -66.209 1.00 24.08  ? 125 VAL C C   1 
ATOM   8064  O  O   . VAL D 1 125 ? -23.132 47.470  -65.114 1.00 20.28  ? 125 VAL C O   1 
ATOM   8065  C  CB  . VAL D 1 125 ? -22.923 48.620  -68.127 1.00 25.56  ? 125 VAL C CB  1 
ATOM   8066  C  CG1 . VAL D 1 125 ? -22.157 49.515  -67.195 1.00 27.90  ? 125 VAL C CG1 1 
ATOM   8067  C  CG2 . VAL D 1 125 ? -21.985 47.782  -68.991 1.00 24.24  ? 125 VAL C CG2 1 
ATOM   8068  N  N   . TYR D 1 126 ? -23.196 45.650  -66.444 1.00 25.20  ? 126 TYR C N   1 
ATOM   8069  C  CA  . TYR D 1 126 ? -22.622 44.760  -65.444 1.00 26.16  ? 126 TYR C CA  1 
ATOM   8070  C  C   . TYR D 1 126 ? -21.919 43.616  -66.166 1.00 22.23  ? 126 TYR C C   1 
ATOM   8071  O  O   . TYR D 1 126 ? -22.214 43.306  -67.321 1.00 20.32  ? 126 TYR C O   1 
ATOM   8072  C  CB  . TYR D 1 126 ? -23.689 44.223  -64.460 1.00 25.50  ? 126 TYR C CB  1 
ATOM   8073  C  CG  . TYR D 1 126 ? -24.861 43.509  -65.126 1.00 28.02  ? 126 TYR C CG  1 
ATOM   8074  C  CD1 . TYR D 1 126 ? -25.975 44.221  -65.591 1.00 26.73  ? 126 TYR C CD1 1 
ATOM   8075  C  CD2 . TYR D 1 126 ? -24.852 42.121  -65.295 1.00 25.18  ? 126 TYR C CD2 1 
ATOM   8076  C  CE1 . TYR D 1 126 ? -27.039 43.563  -66.208 1.00 25.97  ? 126 TYR C CE1 1 
ATOM   8077  C  CE2 . TYR D 1 126 ? -25.903 41.465  -65.905 1.00 22.87  ? 126 TYR C CE2 1 
ATOM   8078  C  CZ  . TYR D 1 126 ? -26.987 42.182  -66.363 1.00 26.43  ? 126 TYR C CZ  1 
ATOM   8079  O  OH  . TYR D 1 126 ? -28.028 41.512  -66.967 1.00 27.13  ? 126 TYR C OH  1 
ATOM   8080  N  N   . GLN D 1 127 ? -20.976 43.002  -65.470 1.00 22.37  ? 127 GLN C N   1 
ATOM   8081  C  CA  . GLN D 1 127 ? -20.284 41.822  -65.955 1.00 24.24  ? 127 GLN C CA  1 
ATOM   8082  C  C   . GLN D 1 127 ? -21.008 40.552  -65.544 1.00 30.54  ? 127 GLN C C   1 
ATOM   8083  O  O   . GLN D 1 127 ? -21.530 40.457  -64.431 1.00 27.74  ? 127 GLN C O   1 
ATOM   8084  C  CB  . GLN D 1 127 ? -18.876 41.777  -65.383 1.00 24.18  ? 127 GLN C CB  1 
ATOM   8085  C  CG  . GLN D 1 127 ? -17.924 42.658  -66.068 1.00 26.16  ? 127 GLN C CG  1 
ATOM   8086  C  CD  . GLN D 1 127 ? -17.461 42.089  -67.396 1.00 27.81  ? 127 GLN C CD  1 
ATOM   8087  O  OE1 . GLN D 1 127 ? -17.860 42.569  -68.450 1.00 27.58  ? 127 GLN C OE1 1 
ATOM   8088  N  NE2 . GLN D 1 127 ? -16.615 41.069  -67.349 1.00 27.53  ? 127 GLN C NE2 1 
ATOM   8089  N  N   . CYS D 1 128 ? -20.974 39.555  -66.425 1.00 29.68  ? 128 CYS C N   1 
ATOM   8090  C  CA  . CYS D 1 128 ? -21.290 38.187  -66.037 1.00 37.11  ? 128 CYS C CA  1 
ATOM   8091  C  C   . CYS D 1 128 ? -20.544 37.235  -66.970 1.00 32.78  ? 128 CYS C C   1 
ATOM   8092  O  O   . CYS D 1 128 ? -19.852 37.655  -67.905 1.00 29.07  ? 128 CYS C O   1 
ATOM   8093  C  CB  . CYS D 1 128 ? -22.792 37.896  -66.076 1.00 30.37  ? 128 CYS C CB  1 
ATOM   8094  S  SG  . CYS D 1 128 ? -23.573 38.377  -67.602 1.00 42.65  ? 128 CYS C SG  1 
ATOM   8095  N  N   . ALA D 1 129 ? -20.684 35.943  -66.701 1.00 26.34  ? 129 ALA C N   1 
ATOM   8096  C  CA  . ALA D 1 129 ? -19.926 34.923  -67.402 1.00 26.84  ? 129 ALA C CA  1 
ATOM   8097  C  C   . ALA D 1 129 ? -20.880 33.876  -67.949 1.00 22.56  ? 129 ALA C C   1 
ATOM   8098  O  O   . ALA D 1 129 ? -21.931 33.609  -67.366 1.00 24.72  ? 129 ALA C O   1 
ATOM   8099  C  CB  . ALA D 1 129 ? -18.888 34.279  -66.487 1.00 27.08  ? 129 ALA C CB  1 
ATOM   8100  N  N   . MET D 1 130 ? -20.485 33.264  -69.060 1.00 25.49  ? 130 MET C N   1 
ATOM   8101  C  CA  . MET D 1 130 ? -21.269 32.138  -69.609 1.00 24.24  ? 130 MET C CA  1 
ATOM   8102  C  C   . MET D 1 130 ? -20.965 30.912  -68.749 1.00 22.58  ? 130 MET C C   1 
ATOM   8103  O  O   . MET D 1 130 ? -19.803 30.579  -68.605 1.00 24.45  ? 130 MET C O   1 
ATOM   8104  C  CB  . MET D 1 130 ? -20.914 31.850  -71.066 1.00 25.47  ? 130 MET C CB  1 
ATOM   8105  C  CG  . MET D 1 130 ? -21.621 30.645  -71.633 1.00 25.70  ? 130 MET C CG  1 
ATOM   8106  S  SD  . MET D 1 130 ? -23.344 30.986  -72.024 1.00 29.05  ? 130 MET C SD  1 
ATOM   8107  C  CE  . MET D 1 130 ? -23.184 32.504  -72.959 1.00 23.75  ? 130 MET C CE  1 
ATOM   8108  N  N   . ARG D 1 131 ? -22.000 30.310  -68.186 1.00 19.09  ? 131 ARG C N   1 
ATOM   8109  C  CA  . ARG D 1 131 ? -21.817 29.142  -67.303 1.00 25.87  ? 131 ARG C CA  1 
ATOM   8110  C  C   . ARG D 1 131 ? -21.695 27.864  -68.145 1.00 26.53  ? 131 ARG C C   1 
ATOM   8111  O  O   . ARG D 1 131 ? -22.085 27.888  -69.313 1.00 23.35  ? 131 ARG C O   1 
ATOM   8112  C  CB  . ARG D 1 131 ? -22.914 29.104  -66.238 1.00 24.28  ? 131 ARG C CB  1 
ATOM   8113  C  CG  . ARG D 1 131 ? -23.236 30.449  -65.606 1.00 28.34  ? 131 ARG C CG  1 
ATOM   8114  C  CD  . ARG D 1 131 ? -22.215 30.941  -64.603 1.00 26.84  ? 131 ARG C CD  1 
ATOM   8115  N  NE  . ARG D 1 131 ? -21.668 29.897  -63.753 1.00 30.38  ? 131 ARG C NE  1 
ATOM   8116  C  CZ  . ARG D 1 131 ? -20.669 30.080  -62.899 1.00 31.84  ? 131 ARG C CZ  1 
ATOM   8117  N  NH1 . ARG D 1 131 ? -20.111 31.270  -62.783 1.00 26.44  ? 131 ARG C NH1 1 
ATOM   8118  N  NH2 . ARG D 1 131 ? -20.228 29.078  -62.163 1.00 29.24  ? 131 ARG C NH2 1 
ATOM   8119  N  N   . HIS D 1 132 ? -21.136 26.814  -67.549 1.00 33.15  ? 132 HIS C N   1 
ATOM   8120  C  CA  . HIS D 1 132 ? -20.922 25.519  -68.247 1.00 32.34  ? 132 HIS C CA  1 
ATOM   8121  C  C   . HIS D 1 132 ? -22.276 24.916  -68.635 1.00 28.68  ? 132 HIS C C   1 
ATOM   8122  O  O   . HIS D 1 132 ? -22.284 24.134  -69.577 1.00 30.04  ? 132 HIS C O   1 
ATOM   8123  C  CB  . HIS D 1 132 ? -19.963 24.645  -67.417 1.00 26.01  ? 132 HIS C CB  1 
ATOM   8124  C  CG  . HIS D 1 132 ? -18.543 25.090  -67.460 1.00 26.45  ? 132 HIS C CG  1 
ATOM   8125  N  ND1 . HIS D 1 132 ? -17.983 25.855  -66.465 1.00 34.65  ? 132 HIS C ND1 1 
ATOM   8126  C  CD2 . HIS D 1 132 ? -17.569 24.878  -68.368 1.00 29.26  ? 132 HIS C CD2 1 
ATOM   8127  C  CE1 . HIS D 1 132 ? -16.726 26.102  -66.760 1.00 33.18  ? 132 HIS C CE1 1 
ATOM   8128  N  NE2 . HIS D 1 132 ? -16.449 25.514  -67.921 1.00 30.92  ? 132 HIS C NE2 1 
ATOM   8129  N  N   . ASN D 1 133 ? -23.361 25.291  -67.960 1.00 28.02  ? 133 ASN C N   1 
ATOM   8130  C  CA  . ASN D 1 133 ? -24.738 24.873  -68.352 1.00 25.82  ? 133 ASN C CA  1 
ATOM   8131  C  C   . ASN D 1 133 ? -25.288 25.834  -69.416 1.00 26.95  ? 133 ASN C C   1 
ATOM   8132  O  O   . ASN D 1 133 ? -26.488 25.781  -69.673 1.00 25.97  ? 133 ASN C O   1 
ATOM   8133  C  CB  . ASN D 1 133 ? -25.659 24.761  -67.136 1.00 29.53  ? 133 ASN C CB  1 
ATOM   8134  C  CG  . ASN D 1 133 ? -25.831 26.059  -66.381 1.00 30.14  ? 133 ASN C CG  1 
ATOM   8135  O  OD1 . ASN D 1 133 ? -25.269 27.085  -66.749 1.00 26.24  ? 133 ASN C OD1 1 
ATOM   8136  N  ND2 . ASN D 1 133 ? -26.614 26.017  -65.321 1.00 30.26  ? 133 ASN C ND2 1 
ATOM   8137  N  N   . PHE D 1 134 ? -24.446 26.704  -69.971 1.00 24.88  ? 134 PHE C N   1 
ATOM   8138  C  CA  . PHE D 1 134 ? -24.830 27.639  -71.068 1.00 24.47  ? 134 PHE C CA  1 
ATOM   8139  C  C   . PHE D 1 134 ? -25.861 28.685  -70.620 1.00 26.47  ? 134 PHE C C   1 
ATOM   8140  O  O   . PHE D 1 134 ? -26.628 29.143  -71.458 1.00 26.85  ? 134 PHE C O   1 
ATOM   8141  C  CB  . PHE D 1 134 ? -25.219 26.861  -72.324 1.00 23.20  ? 134 PHE C CB  1 
ATOM   8142  C  CG  . PHE D 1 134 ? -24.083 26.075  -72.915 1.00 31.74  ? 134 PHE C CG  1 
ATOM   8143  C  CD1 . PHE D 1 134 ? -23.090 26.709  -73.639 1.00 29.75  ? 134 PHE C CD1 1 
ATOM   8144  C  CD2 . PHE D 1 134 ? -23.993 24.709  -72.719 1.00 28.54  ? 134 PHE C CD2 1 
ATOM   8145  C  CE1 . PHE D 1 134 ? -22.037 25.988  -74.174 1.00 31.62  ? 134 PHE C CE1 1 
ATOM   8146  C  CE2 . PHE D 1 134 ? -22.937 23.991  -73.254 1.00 29.63  ? 134 PHE C CE2 1 
ATOM   8147  C  CZ  . PHE D 1 134 ? -21.962 24.632  -73.978 1.00 31.49  ? 134 PHE C CZ  1 
ATOM   8148  N  N   . THR D 1 135 ? -25.864 29.047  -69.345 1.00 22.35  ? 135 THR C N   1 
ATOM   8149  C  CA  . THR D 1 135 ? -26.703 30.116  -68.855 1.00 25.67  ? 135 THR C CA  1 
ATOM   8150  C  C   . THR D 1 135 ? -25.820 31.241  -68.334 1.00 25.09  ? 135 THR C C   1 
ATOM   8151  O  O   . THR D 1 135 ? -24.598 31.118  -68.245 1.00 23.92  ? 135 THR C O   1 
ATOM   8152  C  CB  . THR D 1 135 ? -27.628 29.613  -67.756 1.00 22.99  ? 135 THR C CB  1 
ATOM   8153  O  OG1 . THR D 1 135 ? -26.817 29.049  -66.726 1.00 32.23  ? 135 THR C OG1 1 
ATOM   8154  C  CG2 . THR D 1 135 ? -28.569 28.556  -68.291 1.00 27.45  ? 135 THR C CG2 1 
ATOM   8155  N  N   . ILE D 1 136 ? -26.461 32.346  -67.967 1.00 21.39  ? 136 ILE C N   1 
ATOM   8156  C  CA  . ILE D 1 136 ? -25.780 33.429  -67.291 1.00 20.88  ? 136 ILE C CA  1 
ATOM   8157  C  C   . ILE D 1 136 ? -26.645 33.837  -66.109 1.00 22.26  ? 136 ILE C C   1 
ATOM   8158  O  O   . ILE D 1 136 ? -27.851 33.597  -66.078 1.00 25.05  ? 136 ILE C O   1 
ATOM   8159  C  CB  . ILE D 1 136 ? -25.501 34.624  -68.244 1.00 23.45  ? 136 ILE C CB  1 
ATOM   8160  C  CG1 . ILE D 1 136 ? -26.794 35.303  -68.684 1.00 25.80  ? 136 ILE C CG1 1 
ATOM   8161  C  CG2 . ILE D 1 136 ? -24.825 34.171  -69.524 1.00 19.19  ? 136 ILE C CG2 1 
ATOM   8162  C  CD1 . ILE D 1 136 ? -26.556 36.625  -69.365 1.00 17.36  ? 136 ILE C CD1 1 
ATOM   8163  N  N   . LYS D 1 137 ? -26.008 34.445  -65.122 1.00 26.01  ? 137 LYS C N   1 
ATOM   8164  C  CA  . LYS D 1 137 ? -26.679 34.954  -63.928 1.00 26.91  ? 137 LYS C CA  1 
ATOM   8165  C  C   . LYS D 1 137 ? -26.752 36.460  -64.116 1.00 24.16  ? 137 LYS C C   1 
ATOM   8166  O  O   . LYS D 1 137 ? -25.873 37.195  -63.690 1.00 29.22  ? 137 LYS C O   1 
ATOM   8167  C  CB  . LYS D 1 137 ? -25.909 34.574  -62.667 1.00 25.69  ? 137 LYS C CB  1 
ATOM   8168  C  CG  . LYS D 1 137 ? -25.735 33.057  -62.488 1.00 32.33  ? 137 LYS C CG  1 
ATOM   8169  C  CD  . LYS D 1 137 ? -24.726 32.723  -61.376 1.00 38.01  ? 137 LYS C CD  1 
ATOM   8170  C  CE  . LYS D 1 137 ? -24.767 31.237  -60.984 1.00 42.46  ? 137 LYS C CE  1 
ATOM   8171  N  NZ  . LYS D 1 137 ? -23.694 30.864  -59.993 1.00 45.29  ? 137 LYS C NZ  1 
ATOM   8172  N  N   . GLY D 1 138 ? -27.805 36.930  -64.780 1.00 24.40  ? 138 GLY C N   1 
ATOM   8173  C  CA  . GLY D 1 138 ? -27.958 38.329  -65.075 1.00 23.85  ? 138 GLY C CA  1 
ATOM   8174  C  C   . GLY D 1 138 ? -29.046 38.999  -64.261 1.00 24.66  ? 138 GLY C C   1 
ATOM   8175  O  O   . GLY D 1 138 ? -29.569 38.465  -63.283 1.00 27.06  ? 138 GLY C O   1 
ATOM   8176  N  N   . SER D 1 139 ? -29.414 40.184  -64.715 1.00 27.33  ? 139 SER C N   1 
ATOM   8177  C  CA  . SER D 1 139 ? -30.473 40.959  -64.073 1.00 28.34  ? 139 SER C CA  1 
ATOM   8178  C  C   . SER D 1 139 ? -31.291 41.493  -65.232 1.00 21.30  ? 139 SER C C   1 
ATOM   8179  O  O   . SER D 1 139 ? -30.874 42.432  -65.910 1.00 27.82  ? 139 SER C O   1 
ATOM   8180  C  CB  . SER D 1 139 ? -29.934 42.073  -63.184 1.00 24.85  ? 139 SER C CB  1 
ATOM   8181  O  OG  . SER D 1 139 ? -30.948 43.011  -62.859 1.00 33.19  ? 139 SER C OG  1 
ATOM   8182  N  N   . PHE D 1 140 ? -32.411 40.837  -65.492 1.00 24.12  ? 140 PHE C N   1 
ATOM   8183  C  CA  . PHE D 1 140 ? -33.189 41.076  -66.691 1.00 25.50  ? 140 PHE C CA  1 
ATOM   8184  C  C   . PHE D 1 140 ? -34.647 41.102  -66.285 1.00 29.56  ? 140 PHE C C   1 
ATOM   8185  O  O   . PHE D 1 140 ? -35.124 40.163  -65.634 1.00 24.66  ? 140 PHE C O   1 
ATOM   8186  C  CB  . PHE D 1 140 ? -32.965 39.977  -67.745 1.00 23.25  ? 140 PHE C CB  1 
ATOM   8187  C  CG  . PHE D 1 140 ? -31.591 39.985  -68.381 1.00 26.21  ? 140 PHE C CG  1 
ATOM   8188  C  CD1 . PHE D 1 140 ? -31.241 40.957  -69.300 1.00 22.22  ? 140 PHE C CD1 1 
ATOM   8189  C  CD2 . PHE D 1 140 ? -30.664 38.981  -68.099 1.00 25.01  ? 140 PHE C CD2 1 
ATOM   8190  C  CE1 . PHE D 1 140 ? -29.995 40.941  -69.911 1.00 22.50  ? 140 PHE C CE1 1 
ATOM   8191  C  CE2 . PHE D 1 140 ? -29.398 38.983  -68.705 1.00 22.69  ? 140 PHE C CE2 1 
ATOM   8192  C  CZ  . PHE D 1 140 ? -29.072 39.954  -69.603 1.00 18.92  ? 140 PHE C CZ  1 
ATOM   8193  N  N   . LEU D 1 141 ? -35.357 42.141  -66.696 1.00 22.07  ? 141 LEU C N   1 
ATOM   8194  C  CA  . LEU D 1 141 ? -36.777 42.251  -66.418 1.00 28.71  ? 141 LEU C CA  1 
ATOM   8195  C  C   . LEU D 1 141 ? -37.541 42.155  -67.727 1.00 28.96  ? 141 LEU C C   1 
ATOM   8196  O  O   . LEU D 1 141 ? -36.954 42.067  -68.809 1.00 27.67  ? 141 LEU C O   1 
ATOM   8197  C  CB  . LEU D 1 141 ? -37.108 43.564  -65.688 1.00 26.80  ? 141 LEU C CB  1 
ATOM   8198  C  CG  . LEU D 1 141 ? -36.481 43.810  -64.315 1.00 33.03  ? 141 LEU C CG  1 
ATOM   8199  C  CD1 . LEU D 1 141 ? -36.722 45.241  -63.833 1.00 30.14  ? 141 LEU C CD1 1 
ATOM   8200  C  CD2 . LEU D 1 141 ? -37.019 42.775  -63.293 1.00 25.97  ? 141 LEU C CD2 1 
ATOM   8201  N  N   . ASN D 1 142 ? -38.867 42.176  -67.616 1.00 33.67  ? 142 ASN C N   1 
ATOM   8202  C  CA  . ASN D 1 142 ? -39.721 42.269  -68.793 1.00 35.08  ? 142 ASN C CA  1 
ATOM   8203  C  C   . ASN D 1 142 ? -39.306 43.469  -69.636 1.00 29.18  ? 142 ASN C C   1 
ATOM   8204  O  O   . ASN D 1 142 ? -39.163 44.581  -69.129 1.00 22.70  ? 142 ASN C O   1 
ATOM   8205  C  CB  . ASN D 1 142 ? -41.183 42.383  -68.356 1.00 31.72  ? 142 ASN C CB  1 
ATOM   8206  C  CG  . ASN D 1 142 ? -41.719 41.074  -67.796 1.00 40.00  ? 142 ASN C CG  1 
ATOM   8207  O  OD1 . ASN D 1 142 ? -42.593 41.095  -66.938 1.00 34.45  ? 142 ASN C OD1 1 
ATOM   8208  N  ND2 . ASN D 1 142 ? -41.234 39.934  -68.306 1.00 46.48  ? 142 ASN C ND2 1 
ATOM   8209  N  N   . GLY D 1 143 ? -39.088 43.232  -70.917 1.00 28.77  ? 143 GLY C N   1 
ATOM   8210  C  CA  . GLY D 1 143 ? -38.649 44.279  -71.803 1.00 27.85  ? 143 GLY C CA  1 
ATOM   8211  C  C   . GLY D 1 143 ? -37.155 44.344  -71.982 1.00 25.71  ? 143 GLY C C   1 
ATOM   8212  O  O   . GLY D 1 143 ? -36.681 45.138  -72.804 1.00 27.19  ? 143 GLY C O   1 
ATOM   8213  N  N   . SER D 1 144 ? -36.398 43.509  -71.274 1.00 22.89  ? 144 SER C N   1 
ATOM   8214  C  CA  . SER D 1 144 ? -34.952 43.496  -71.427 1.00 20.69  ? 144 SER C CA  1 
ATOM   8215  C  C   . SER D 1 144 ? -34.504 42.728  -72.659 1.00 23.83  ? 144 SER C C   1 
ATOM   8216  O  O   . SER D 1 144 ? -33.311 42.747  -72.965 1.00 22.45  ? 144 SER C O   1 
ATOM   8217  C  CB  . SER D 1 144 ? -34.275 42.902  -70.177 1.00 23.06  ? 144 SER C CB  1 
ATOM   8218  O  OG  . SER D 1 144 ? -34.685 41.551  -69.907 1.00 24.23  ? 144 SER C OG  1 
ATOM   8219  N  N   . CYS D 1 145 ? -35.411 42.028  -73.348 1.00 24.51  ? 145 CYS C N   1 
ATOM   8220  C  CA  . CYS D 1 145 ? -35.018 41.244  -74.517 1.00 24.67  ? 145 CYS C CA  1 
ATOM   8221  C  C   . CYS D 1 145 ? -34.396 42.121  -75.593 1.00 23.44  ? 145 CYS C C   1 
ATOM   8222  O  O   . CYS D 1 145 ? -34.852 43.238  -75.842 1.00 24.34  ? 145 CYS C O   1 
ATOM   8223  C  CB  . CYS D 1 145 ? -36.214 40.476  -75.083 1.00 22.88  ? 145 CYS C CB  1 
ATOM   8224  S  SG  . CYS D 1 145 ? -36.724 39.069  -74.029 1.00 29.50  ? 145 CYS C SG  1 
ATOM   8225  N  N   . GLY D 1 146 ? -33.352 41.596  -76.249 1.00 23.29  ? 146 GLY C N   1 
ATOM   8226  C  CA  . GLY D 1 146 ? -32.584 42.377  -77.189 1.00 21.21  ? 146 GLY C CA  1 
ATOM   8227  C  C   . GLY D 1 146 ? -31.416 43.141  -76.593 1.00 19.18  ? 146 GLY C C   1 
ATOM   8228  O  O   . GLY D 1 146 ? -30.678 43.785  -77.343 1.00 25.63  ? 146 GLY C O   1 
ATOM   8229  N  N   . SER D 1 147 ? -31.280 43.180  -75.267 1.00 21.86  ? 147 SER C N   1 
ATOM   8230  C  CA  . SER D 1 147 ? -30.046 43.657  -74.662 1.00 20.65  ? 147 SER C CA  1 
ATOM   8231  C  C   . SER D 1 147 ? -28.902 42.727  -75.043 1.00 22.57  ? 147 SER C C   1 
ATOM   8232  O  O   . SER D 1 147 ? -29.094 41.509  -75.203 1.00 17.92  ? 147 SER C O   1 
ATOM   8233  C  CB  . SER D 1 147 ? -30.187 43.727  -73.146 1.00 21.24  ? 147 SER C CB  1 
ATOM   8234  O  OG  . SER D 1 147 ? -31.282 44.558  -72.796 1.00 18.15  ? 147 SER C OG  1 
ATOM   8235  N  N   . VAL D 1 148 ? -27.703 43.301  -75.195 1.00 15.15  ? 148 VAL C N   1 
ATOM   8236  C  CA  . VAL D 1 148 ? -26.598 42.533  -75.741 1.00 18.44  ? 148 VAL C CA  1 
ATOM   8237  C  C   . VAL D 1 148 ? -25.447 42.439  -74.743 1.00 18.28  ? 148 VAL C C   1 
ATOM   8238  O  O   . VAL D 1 148 ? -25.307 43.240  -73.811 1.00 20.71  ? 148 VAL C O   1 
ATOM   8239  C  CB  . VAL D 1 148 ? -26.124 43.081  -77.110 1.00 19.06  ? 148 VAL C CB  1 
ATOM   8240  C  CG1 . VAL D 1 148 ? -27.258 43.006  -78.072 1.00 18.47  ? 148 VAL C CG1 1 
ATOM   8241  C  CG2 . VAL D 1 148 ? -25.586 44.485  -77.010 1.00 17.28  ? 148 VAL C CG2 1 
ATOM   8242  N  N   . GLY D 1 149 ? -24.657 41.388  -74.916 1.00 14.38  ? 149 GLY C N   1 
ATOM   8243  C  CA  . GLY D 1 149 ? -23.438 41.188  -74.160 1.00 17.64  ? 149 GLY C CA  1 
ATOM   8244  C  C   . GLY D 1 149 ? -22.255 41.351  -75.091 1.00 22.13  ? 149 GLY C C   1 
ATOM   8245  O  O   . GLY D 1 149 ? -22.349 41.066  -76.287 1.00 22.57  ? 149 GLY C O   1 
ATOM   8246  N  N   . PHE D 1 150 ? -21.139 41.815  -74.553 1.00 20.45  ? 150 PHE C N   1 
ATOM   8247  C  CA  . PHE D 1 150 ? -20.080 42.225  -75.460 1.00 24.64  ? 150 PHE C CA  1 
ATOM   8248  C  C   . PHE D 1 150 ? -18.756 42.299  -74.722 1.00 21.44  ? 150 PHE C C   1 
ATOM   8249  O  O   . PHE D 1 150 ? -18.702 42.429  -73.496 1.00 22.24  ? 150 PHE C O   1 
ATOM   8250  C  CB  . PHE D 1 150 ? -20.387 43.584  -76.125 1.00 20.59  ? 150 PHE C CB  1 
ATOM   8251  C  CG  . PHE D 1 150 ? -20.527 44.716  -75.144 1.00 23.80  ? 150 PHE C CG  1 
ATOM   8252  C  CD1 . PHE D 1 150 ? -21.733 44.963  -74.507 1.00 23.31  ? 150 PHE C CD1 1 
ATOM   8253  C  CD2 . PHE D 1 150 ? -19.437 45.506  -74.812 1.00 20.55  ? 150 PHE C CD2 1 
ATOM   8254  C  CE1 . PHE D 1 150 ? -21.844 46.009  -73.588 1.00 23.38  ? 150 PHE C CE1 1 
ATOM   8255  C  CE2 . PHE D 1 150 ? -19.553 46.544  -73.891 1.00 18.05  ? 150 PHE C CE2 1 
ATOM   8256  C  CZ  . PHE D 1 150 ? -20.746 46.792  -73.285 1.00 17.06  ? 150 PHE C CZ  1 
ATOM   8257  N  N   . ASN D 1 151 ? -17.688 42.200  -75.503 1.00 21.49  ? 151 ASN C N   1 
ATOM   8258  C  CA  . ASN D 1 151 ? -16.347 42.528  -75.063 1.00 23.82  ? 151 ASN C CA  1 
ATOM   8259  C  C   . ASN D 1 151 ? -15.814 43.579  -76.012 1.00 26.88  ? 151 ASN C C   1 
ATOM   8260  O  O   . ASN D 1 151 ? -16.278 43.705  -77.148 1.00 28.23  ? 151 ASN C O   1 
ATOM   8261  C  CB  . ASN D 1 151 ? -15.415 41.300  -75.049 1.00 24.59  ? 151 ASN C CB  1 
ATOM   8262  C  CG  . ASN D 1 151 ? -15.700 40.353  -73.879 1.00 27.69  ? 151 ASN C CG  1 
ATOM   8263  O  OD1 . ASN D 1 151 ? -16.466 39.387  -74.012 1.00 27.44  ? 151 ASN C OD1 1 
ATOM   8264  N  ND2 . ASN D 1 151 ? -15.065 40.616  -72.734 1.00 27.61  ? 151 ASN C ND2 1 
ATOM   8265  N  N   . ILE D 1 152 ? -14.833 44.330  -75.531 1.00 30.00  ? 152 ILE C N   1 
ATOM   8266  C  CA  . ILE D 1 152 ? -14.147 45.343  -76.317 1.00 35.53  ? 152 ILE C CA  1 
ATOM   8267  C  C   . ILE D 1 152 ? -12.668 45.016  -76.298 1.00 35.69  ? 152 ILE C C   1 
ATOM   8268  O  O   . ILE D 1 152 ? -12.074 44.876  -75.226 1.00 38.53  ? 152 ILE C O   1 
ATOM   8269  C  CB  . ILE D 1 152 ? -14.377 46.766  -75.772 1.00 33.52  ? 152 ILE C CB  1 
ATOM   8270  C  CG1 . ILE D 1 152 ? -15.860 47.002  -75.467 1.00 32.23  ? 152 ILE C CG1 1 
ATOM   8271  C  CG2 . ILE D 1 152 ? -13.823 47.804  -76.746 1.00 29.95  ? 152 ILE C CG2 1 
ATOM   8272  C  CD1 . ILE D 1 152 ? -16.194 48.453  -75.164 1.00 32.10  ? 152 ILE C CD1 1 
ATOM   8273  N  N   . ASP D 1 153 ? -12.072 44.919  -77.471 1.00 41.83  ? 153 ASP C N   1 
ATOM   8274  C  CA  . ASP D 1 153 ? -10.633 44.749  -77.586 1.00 48.05  ? 153 ASP C CA  1 
ATOM   8275  C  C   . ASP D 1 153 ? -10.089 45.923  -78.384 1.00 46.66  ? 153 ASP C C   1 
ATOM   8276  O  O   . ASP D 1 153 ? -10.341 46.023  -79.591 1.00 42.58  ? 153 ASP C O   1 
ATOM   8277  C  CB  . ASP D 1 153 ? -10.279 43.429  -78.253 1.00 51.20  ? 153 ASP C CB  1 
ATOM   8278  C  CG  . ASP D 1 153 ? -8.802  43.192  -78.260 1.00 59.74  ? 153 ASP C CG  1 
ATOM   8279  O  OD1 . ASP D 1 153 ? -8.240  43.009  -77.158 1.00 70.02  ? 153 ASP C OD1 1 
ATOM   8280  O  OD2 . ASP D 1 153 ? -8.198  43.239  -79.350 1.00 59.25  ? 153 ASP C OD2 1 
ATOM   8281  N  N   . TYR D 1 154 ? -9.351  46.805  -77.704 1.00 49.06  ? 154 TYR C N   1 
ATOM   8282  C  CA  . TYR D 1 154 ? -8.852  48.041  -78.296 1.00 49.49  ? 154 TYR C CA  1 
ATOM   8283  C  C   . TYR D 1 154 ? -10.023 48.904  -78.762 1.00 48.82  ? 154 TYR C C   1 
ATOM   8284  O  O   . TYR D 1 154 ? -10.600 49.663  -77.975 1.00 50.31  ? 154 TYR C O   1 
ATOM   8285  C  CB  . TYR D 1 154 ? -7.861  47.760  -79.438 1.00 44.91  ? 154 TYR C CB  1 
ATOM   8286  C  CG  . TYR D 1 154 ? -7.067  48.984  -79.848 0.00 44.20  ? 154 TYR C CG  1 
ATOM   8287  C  CD1 . TYR D 1 154 ? -6.459  49.793  -78.897 0.00 42.57  ? 154 TYR C CD1 1 
ATOM   8288  C  CD2 . TYR D 1 154 ? -6.931  49.330  -81.185 0.00 44.35  ? 154 TYR C CD2 1 
ATOM   8289  C  CE1 . TYR D 1 154 ? -5.739  50.915  -79.270 0.00 40.52  ? 154 TYR C CE1 1 
ATOM   8290  C  CE2 . TYR D 1 154 ? -6.215  50.447  -81.567 0.00 42.70  ? 154 TYR C CE2 1 
ATOM   8291  C  CZ  . TYR D 1 154 ? -5.620  51.236  -80.606 0.00 40.06  ? 154 TYR C CZ  1 
ATOM   8292  O  OH  . TYR D 1 154 ? -4.905  52.348  -80.986 0.00 38.90  ? 154 TYR C OH  1 
ATOM   8293  N  N   . ASP D 1 155 ? -10.385 48.810  -80.033 1.00 44.64  ? 155 ASP C N   1 
ATOM   8294  C  CA  . ASP D 1 155 ? -11.504 49.580  -80.546 1.00 46.70  ? 155 ASP C CA  1 
ATOM   8295  C  C   . ASP D 1 155 ? -12.646 48.725  -81.096 1.00 43.58  ? 155 ASP C C   1 
ATOM   8296  O  O   . ASP D 1 155 ? -13.681 49.284  -81.485 1.00 41.93  ? 155 ASP C O   1 
ATOM   8297  C  CB  . ASP D 1 155 ? -10.996 50.564  -81.613 1.00 48.36  ? 155 ASP C CB  1 
ATOM   8298  C  CG  . ASP D 1 155 ? -10.111 49.893  -82.663 1.00 56.28  ? 155 ASP C CG  1 
ATOM   8299  O  OD1 . ASP D 1 155 ? -9.604  48.775  -82.409 1.00 54.48  ? 155 ASP C OD1 1 
ATOM   8300  O  OD2 . ASP D 1 155 ? -9.889  50.508  -83.729 1.00 57.47  ? 155 ASP C OD2 1 
ATOM   8301  N  N   . CYS D 1 156 ? -12.502 47.398  -81.122 1.00 37.33  ? 156 CYS C N   1 
ATOM   8302  C  CA  . CYS D 1 156 ? -13.476 46.509  -81.744 1.00 36.03  ? 156 CYS C CA  1 
ATOM   8303  C  C   . CYS D 1 156 ? -14.455 45.949  -80.720 1.00 34.90  ? 156 CYS C C   1 
ATOM   8304  O  O   . CYS D 1 156 ? -14.055 45.392  -79.690 1.00 33.83  ? 156 CYS C O   1 
ATOM   8305  C  CB  . CYS D 1 156 ? -12.782 45.359  -82.472 1.00 37.42  ? 156 CYS C CB  1 
ATOM   8306  S  SG  . CYS D 1 156 ? -13.942 44.317  -83.418 1.00 38.70  ? 156 CYS C SG  1 
ATOM   8307  N  N   . VAL D 1 157 ? -15.736 46.061  -81.022 1.00 30.32  ? 157 VAL C N   1 
ATOM   8308  C  CA  . VAL D 1 157 ? -16.765 45.491  -80.166 1.00 29.63  ? 157 VAL C CA  1 
ATOM   8309  C  C   . VAL D 1 157 ? -17.072 44.087  -80.668 1.00 29.69  ? 157 VAL C C   1 
ATOM   8310  O  O   . VAL D 1 157 ? -17.451 43.904  -81.830 1.00 22.37  ? 157 VAL C O   1 
ATOM   8311  C  CB  . VAL D 1 157 ? -18.028 46.361  -80.168 1.00 26.64  ? 157 VAL C CB  1 
ATOM   8312  C  CG1 . VAL D 1 157 ? -19.044 45.798  -79.190 1.00 23.13  ? 157 VAL C CG1 1 
ATOM   8313  C  CG2 . VAL D 1 157 ? -17.669 47.811  -79.886 1.00 23.76  ? 157 VAL C CG2 1 
ATOM   8314  N  N   . SER D 1 158 ? -16.903 43.090  -79.802 1.00 25.11  ? 158 SER C N   1 
ATOM   8315  C  CA  . SER D 1 158 ? -17.288 41.722  -80.125 1.00 22.93  ? 158 SER C CA  1 
ATOM   8316  C  C   . SER D 1 158 ? -18.605 41.435  -79.416 1.00 22.68  ? 158 SER C C   1 
ATOM   8317  O  O   . SER D 1 158 ? -18.637 41.234  -78.200 1.00 25.49  ? 158 SER C O   1 
ATOM   8318  C  CB  . SER D 1 158 ? -16.207 40.739  -79.721 1.00 24.44  ? 158 SER C CB  1 
ATOM   8319  O  OG  . SER D 1 158 ? -15.145 40.812  -80.632 1.00 31.35  ? 158 SER C OG  1 
ATOM   8320  N  N   . PHE D 1 159 ? -19.691 41.451  -80.173 1.00 21.40  ? 159 PHE C N   1 
ATOM   8321  C  CA  . PHE D 1 159 ? -21.004 41.151  -79.629 1.00 25.66  ? 159 PHE C CA  1 
ATOM   8322  C  C   . PHE D 1 159 ? -21.120 39.637  -79.530 1.00 23.26  ? 159 PHE C C   1 
ATOM   8323  O  O   . PHE D 1 159 ? -20.971 38.937  -80.537 1.00 23.75  ? 159 PHE C O   1 
ATOM   8324  C  CB  . PHE D 1 159 ? -22.106 41.716  -80.530 1.00 21.93  ? 159 PHE C CB  1 
ATOM   8325  C  CG  . PHE D 1 159 ? -22.129 43.229  -80.629 1.00 24.42  ? 159 PHE C CG  1 
ATOM   8326  C  CD1 . PHE D 1 159 ? -22.647 44.006  -79.606 1.00 24.12  ? 159 PHE C CD1 1 
ATOM   8327  C  CD2 . PHE D 1 159 ? -21.673 43.865  -81.768 1.00 22.01  ? 159 PHE C CD2 1 
ATOM   8328  C  CE1 . PHE D 1 159 ? -22.694 45.374  -79.717 1.00 19.36  ? 159 PHE C CE1 1 
ATOM   8329  C  CE2 . PHE D 1 159 ? -21.716 45.231  -81.869 1.00 20.46  ? 159 PHE C CE2 1 
ATOM   8330  C  CZ  . PHE D 1 159 ? -22.227 45.983  -80.843 1.00 18.66  ? 159 PHE C CZ  1 
ATOM   8331  N  N   . CYS D 1 160 ? -21.407 39.131  -78.339 1.00 22.64  ? 160 CYS C N   1 
ATOM   8332  C  CA  . CYS D 1 160 ? -21.482 37.691  -78.132 1.00 28.50  ? 160 CYS C CA  1 
ATOM   8333  C  C   . CYS D 1 160 ? -22.839 37.198  -77.657 1.00 28.46  ? 160 CYS C C   1 
ATOM   8334  O  O   . CYS D 1 160 ? -23.082 35.982  -77.718 1.00 27.98  ? 160 CYS C O   1 
ATOM   8335  C  CB  . CYS D 1 160 ? -20.414 37.224  -77.123 1.00 24.29  ? 160 CYS C CB  1 
ATOM   8336  S  SG  . CYS D 1 160 ? -20.545 37.995  -75.458 1.00 26.62  ? 160 CYS C SG  1 
ATOM   8337  N  N   . TYR D 1 161 ? -23.726 38.077  -77.186 1.00 21.32  ? 161 TYR C N   1 
ATOM   8338  C  CA  . TYR D 1 161 ? -24.919 37.580  -76.509 1.00 22.18  ? 161 TYR C CA  1 
ATOM   8339  C  C   . TYR D 1 161 ? -26.073 38.540  -76.723 1.00 21.09  ? 161 TYR C C   1 
ATOM   8340  O  O   . TYR D 1 161 ? -25.911 39.753  -76.576 1.00 19.93  ? 161 TYR C O   1 
ATOM   8341  C  CB  . TYR D 1 161 ? -24.669 37.405  -75.008 1.00 16.59  ? 161 TYR C CB  1 
ATOM   8342  C  CG  . TYR D 1 161 ? -25.865 36.947  -74.206 1.00 16.49  ? 161 TYR C CG  1 
ATOM   8343  C  CD1 . TYR D 1 161 ? -26.118 35.607  -74.016 1.00 19.80  ? 161 TYR C CD1 1 
ATOM   8344  C  CD2 . TYR D 1 161 ? -26.727 37.860  -73.622 1.00 17.32  ? 161 TYR C CD2 1 
ATOM   8345  C  CE1 . TYR D 1 161 ? -27.210 35.175  -73.249 1.00 23.18  ? 161 TYR C CE1 1 
ATOM   8346  C  CE2 . TYR D 1 161 ? -27.810 37.458  -72.869 1.00 18.92  ? 161 TYR C CE2 1 
ATOM   8347  C  CZ  . TYR D 1 161 ? -28.058 36.111  -72.696 1.00 21.33  ? 161 TYR C CZ  1 
ATOM   8348  O  OH  . TYR D 1 161 ? -29.124 35.689  -71.970 1.00 17.90  ? 161 TYR C OH  1 
ATOM   8349  N  N   . MET D 1 162 ? -27.248 37.991  -77.020 1.00 22.67  ? 162 MET C N   1 
ATOM   8350  C  CA  . MET D 1 162 ? -28.472 38.782  -77.066 1.00 21.25  ? 162 MET C CA  1 
ATOM   8351  C  C   . MET D 1 162 ? -29.543 38.087  -76.245 1.00 22.52  ? 162 MET C C   1 
ATOM   8352  O  O   . MET D 1 162 ? -29.791 36.892  -76.429 1.00 25.41  ? 162 MET C O   1 
ATOM   8353  C  CB  . MET D 1 162 ? -28.939 38.999  -78.496 1.00 18.53  ? 162 MET C CB  1 
ATOM   8354  C  CG  . MET D 1 162 ? -30.290 39.655  -78.543 1.00 21.86  ? 162 MET C CG  1 
ATOM   8355  S  SD  . MET D 1 162 ? -30.856 40.007  -80.202 1.00 28.80  ? 162 MET C SD  1 
ATOM   8356  C  CE  . MET D 1 162 ? -30.002 41.575  -80.509 1.00 19.99  ? 162 MET C CE  1 
ATOM   8357  N  N   . HIS D 1 163 ? -30.185 38.834  -75.350 1.00 23.19  ? 163 HIS C N   1 
ATOM   8358  C  CA  . HIS D 1 163 ? -31.020 38.219  -74.325 1.00 22.60  ? 163 HIS C CA  1 
ATOM   8359  C  C   . HIS D 1 163 ? -32.366 37.766  -74.869 1.00 20.93  ? 163 HIS C C   1 
ATOM   8360  O  O   . HIS D 1 163 ? -32.972 38.427  -75.716 1.00 22.45  ? 163 HIS C O   1 
ATOM   8361  C  CB  . HIS D 1 163 ? -31.245 39.170  -73.151 1.00 19.43  ? 163 HIS C CB  1 
ATOM   8362  C  CG  . HIS D 1 163 ? -32.036 38.547  -72.049 1.00 22.79  ? 163 HIS C CG  1 
ATOM   8363  N  ND1 . HIS D 1 163 ? -31.623 37.405  -71.391 1.00 23.54  ? 163 HIS C ND1 1 
ATOM   8364  C  CD2 . HIS D 1 163 ? -33.251 38.854  -71.539 1.00 23.22  ? 163 HIS C CD2 1 
ATOM   8365  C  CE1 . HIS D 1 163 ? -32.533 37.058  -70.499 1.00 23.23  ? 163 HIS C CE1 1 
ATOM   8366  N  NE2 . HIS D 1 163 ? -33.538 37.914  -70.577 1.00 21.13  ? 163 HIS C NE2 1 
ATOM   8367  N  N   . HIS D 1 164 ? -32.824 36.627  -74.386 1.00 23.82  ? 164 HIS C N   1 
ATOM   8368  C  CA  . HIS D 1 164 ? -34.102 36.074  -74.834 1.00 24.58  ? 164 HIS C CA  1 
ATOM   8369  C  C   . HIS D 1 164 ? -35.017 35.649  -73.700 1.00 22.84  ? 164 HIS C C   1 
ATOM   8370  O  O   . HIS D 1 164 ? -36.225 35.886  -73.772 1.00 22.29  ? 164 HIS C O   1 
ATOM   8371  C  CB  . HIS D 1 164 ? -33.879 34.851  -75.752 1.00 22.07  ? 164 HIS C CB  1 
ATOM   8372  C  CG  . HIS D 1 164 ? -33.591 35.195  -77.174 1.00 24.06  ? 164 HIS C CG  1 
ATOM   8373  N  ND1 . HIS D 1 164 ? -32.402 35.765  -77.575 1.00 24.87  ? 164 HIS C ND1 1 
ATOM   8374  C  CD2 . HIS D 1 164 ? -34.315 35.001  -78.301 1.00 28.05  ? 164 HIS C CD2 1 
ATOM   8375  C  CE1 . HIS D 1 164 ? -32.417 35.934  -78.886 1.00 23.16  ? 164 HIS C CE1 1 
ATOM   8376  N  NE2 . HIS D 1 164 ? -33.566 35.477  -79.352 1.00 23.99  ? 164 HIS C NE2 1 
ATOM   8377  N  N   . MET D 1 165 ? -34.487 35.002  -72.663 1.00 23.45  ? 165 MET C N   1 
ATOM   8378  C  CA  . MET D 1 165 ? -35.412 34.316  -71.782 1.00 22.20  ? 165 MET C CA  1 
ATOM   8379  C  C   . MET D 1 165 ? -34.806 34.043  -70.419 1.00 26.89  ? 165 MET C C   1 
ATOM   8380  O  O   . MET D 1 165 ? -33.586 34.016  -70.233 1.00 24.58  ? 165 MET C O   1 
ATOM   8381  C  CB  . MET D 1 165 ? -35.889 33.014  -72.430 1.00 23.87  ? 165 MET C CB  1 
ATOM   8382  C  CG  . MET D 1 165 ? -34.775 32.097  -72.857 1.00 30.48  ? 165 MET C CG  1 
ATOM   8383  S  SD  . MET D 1 165 ? -35.408 30.588  -73.621 1.00 41.86  ? 165 MET C SD  1 
ATOM   8384  C  CE  . MET D 1 165 ? -36.471 29.975  -72.308 1.00 28.52  ? 165 MET C CE  1 
ATOM   8385  N  N   . GLU D 1 166 ? -35.702 33.831  -69.467 1.00 28.21  ? 166 GLU C N   1 
ATOM   8386  C  CA  . GLU D 1 166 ? -35.351 33.415  -68.127 1.00 25.68  ? 166 GLU C CA  1 
ATOM   8387  C  C   . GLU D 1 166 ? -35.729 31.950  -67.961 1.00 27.63  ? 166 GLU C C   1 
ATOM   8388  O  O   . GLU D 1 166 ? -36.773 31.511  -68.448 1.00 31.13  ? 166 GLU C O   1 
ATOM   8389  C  CB  . GLU D 1 166 ? -36.061 34.290  -67.102 1.00 23.79  ? 166 GLU C CB  1 
ATOM   8390  C  CG  . GLU D 1 166 ? -35.835 33.898  -65.670 1.00 28.29  ? 166 GLU C CG  1 
ATOM   8391  C  CD  . GLU D 1 166 ? -36.157 35.039  -64.707 1.00 37.24  ? 166 GLU C CD  1 
ATOM   8392  O  OE1 . GLU D 1 166 ? -36.228 36.211  -65.158 1.00 32.07  ? 166 GLU C OE1 1 
ATOM   8393  O  OE2 . GLU D 1 166 ? -36.380 34.750  -63.507 1.00 36.40  ? 166 GLU C OE2 1 
ATOM   8394  N  N   . LEU D 1 167 ? -34.880 31.210  -67.269 1.00 29.25  ? 167 LEU C N   1 
ATOM   8395  C  CA  . LEU D 1 167 ? -35.004 29.787  -67.018 1.00 25.75  ? 167 LEU C CA  1 
ATOM   8396  C  C   . LEU D 1 167 ? -35.279 29.520  -65.539 1.00 31.95  ? 167 LEU C C   1 
ATOM   8397  O  O   . LEU D 1 167 ? -35.142 30.420  -64.701 1.00 33.44  ? 167 LEU C O   1 
ATOM   8398  C  CB  . LEU D 1 167 ? -33.707 29.092  -67.446 1.00 26.97  ? 167 LEU C CB  1 
ATOM   8399  C  CG  . LEU D 1 167 ? -33.473 29.050  -68.958 1.00 31.00  ? 167 LEU C CG  1 
ATOM   8400  C  CD1 . LEU D 1 167 ? -32.046 28.634  -69.247 1.00 30.76  ? 167 LEU C CD1 1 
ATOM   8401  C  CD2 . LEU D 1 167 ? -34.455 28.088  -69.599 1.00 33.90  ? 167 LEU C CD2 1 
ATOM   8402  N  N   . PRO D 1 168 ? -35.702 28.299  -65.181 1.00 28.32  ? 168 PRO C N   1 
ATOM   8403  C  CA  . PRO D 1 168 ? -36.006 28.013  -63.776 1.00 32.77  ? 168 PRO C CA  1 
ATOM   8404  C  C   . PRO D 1 168 ? -34.838 28.392  -62.880 1.00 34.58  ? 168 PRO C C   1 
ATOM   8405  O  O   . PRO D 1 168 ? -33.674 28.224  -63.253 1.00 37.50  ? 168 PRO C O   1 
ATOM   8406  C  CB  . PRO D 1 168 ? -36.239 26.500  -63.771 1.00 31.59  ? 168 PRO C CB  1 
ATOM   8407  C  CG  . PRO D 1 168 ? -36.757 26.216  -65.109 1.00 26.88  ? 168 PRO C CG  1 
ATOM   8408  C  CD  . PRO D 1 168 ? -36.017 27.138  -66.030 1.00 32.46  ? 168 PRO C CD  1 
ATOM   8409  N  N   . THR D 1 169 ? -35.167 28.932  -61.704 1.00 35.69  ? 169 THR C N   1 
ATOM   8410  C  CA  . THR D 1 169 ? -34.248 29.393  -60.656 1.00 35.21  ? 169 THR C CA  1 
ATOM   8411  C  C   . THR D 1 169 ? -33.634 30.768  -60.909 1.00 32.42  ? 169 THR C C   1 
ATOM   8412  O  O   . THR D 1 169 ? -32.582 31.083  -60.327 1.00 31.27  ? 169 THR C O   1 
ATOM   8413  C  CB  . THR D 1 169 ? -33.118 28.395  -60.378 1.00 41.38  ? 169 THR C CB  1 
ATOM   8414  O  OG1 . THR D 1 169 ? -32.345 28.179  -61.565 1.00 46.14  ? 169 THR C OG1 1 
ATOM   8415  C  CG2 . THR D 1 169 ? -33.710 27.066  -59.936 1.00 45.47  ? 169 THR C CG2 1 
ATOM   8416  N  N   . GLY D 1 170 ? -34.231 31.588  -61.773 1.00 39.46  ? 170 GLY C N   1 
ATOM   8417  C  CA  . GLY D 1 170 ? -33.747 32.948  -61.988 1.00 29.28  ? 170 GLY C CA  1 
ATOM   8418  C  C   . GLY D 1 170 ? -32.473 33.144  -62.787 1.00 29.86  ? 170 GLY C C   1 
ATOM   8419  O  O   . GLY D 1 170 ? -31.785 34.151  -62.583 1.00 29.90  ? 170 GLY C O   1 
ATOM   8420  N  N   . VAL D 1 171 ? -32.121 32.218  -63.679 1.00 27.09  ? 171 VAL C N   1 
ATOM   8421  C  CA  . VAL D 1 171 ? -30.959 32.435  -64.541 1.00 28.72  ? 171 VAL C CA  1 
ATOM   8422  C  C   . VAL D 1 171 ? -31.449 32.674  -65.961 1.00 25.59  ? 171 VAL C C   1 
ATOM   8423  O  O   . VAL D 1 171 ? -32.647 32.561  -66.251 1.00 26.88  ? 171 VAL C O   1 
ATOM   8424  C  CB  . VAL D 1 171 ? -29.945 31.269  -64.495 1.00 32.85  ? 171 VAL C CB  1 
ATOM   8425  C  CG1 . VAL D 1 171 ? -29.425 31.050  -63.061 1.00 29.10  ? 171 VAL C CG1 1 
ATOM   8426  C  CG2 . VAL D 1 171 ? -30.532 29.988  -65.113 1.00 23.90  ? 171 VAL C CG2 1 
ATOM   8427  N  N   . HIS D 1 172 ? -30.524 32.973  -66.864 1.00 26.41  ? 172 HIS C N   1 
ATOM   8428  C  CA  . HIS D 1 172 ? -30.878 33.611  -68.122 1.00 21.42  ? 172 HIS C CA  1 
ATOM   8429  C  C   . HIS D 1 172 ? -30.212 32.917  -69.294 1.00 21.24  ? 172 HIS C C   1 
ATOM   8430  O  O   . HIS D 1 172 ? -29.125 32.355  -69.177 1.00 23.17  ? 172 HIS C O   1 
ATOM   8431  C  CB  . HIS D 1 172 ? -30.493 35.067  -68.074 1.00 17.59  ? 172 HIS C CB  1 
ATOM   8432  C  CG  . HIS D 1 172 ? -31.172 35.808  -66.971 1.00 23.93  ? 172 HIS C CG  1 
ATOM   8433  N  ND1 . HIS D 1 172 ? -30.536 36.154  -65.798 1.00 22.44  ? 172 HIS C ND1 1 
ATOM   8434  C  CD2 . HIS D 1 172 ? -32.451 36.236  -66.847 1.00 23.14  ? 172 HIS C CD2 1 
ATOM   8435  C  CE1 . HIS D 1 172 ? -31.387 36.789  -65.011 1.00 25.06  ? 172 HIS C CE1 1 
ATOM   8436  N  NE2 . HIS D 1 172 ? -32.557 36.851  -65.624 1.00 23.12  ? 172 HIS C NE2 1 
ATOM   8437  N  N   . ALA D 1 173 ? -30.884 32.986  -70.432 1.00 21.79  ? 173 ALA C N   1 
ATOM   8438  C  CA  . ALA D 1 173 ? -30.467 32.295  -71.635 1.00 24.92  ? 173 ALA C CA  1 
ATOM   8439  C  C   . ALA D 1 173 ? -30.725 33.176  -72.846 1.00 21.95  ? 173 ALA C C   1 
ATOM   8440  O  O   . ALA D 1 173 ? -31.749 33.864  -72.922 1.00 22.08  ? 173 ALA C O   1 
ATOM   8441  C  CB  . ALA D 1 173 ? -31.215 30.962  -71.795 1.00 22.50  ? 173 ALA C CB  1 
ATOM   8442  N  N   . GLY D 1 174 ? -29.825 33.091  -73.814 1.00 17.04  ? 174 GLY C N   1 
ATOM   8443  C  CA  . GLY D 1 174 ? -29.958 33.848  -75.029 1.00 23.42  ? 174 GLY C CA  1 
ATOM   8444  C  C   . GLY D 1 174 ? -29.145 33.225  -76.141 1.00 27.47  ? 174 GLY C C   1 
ATOM   8445  O  O   . GLY D 1 174 ? -28.662 32.089  -76.032 1.00 21.75  ? 174 GLY C O   1 
ATOM   8446  N  N   . THR D 1 175 ? -28.994 34.001  -77.214 1.00 24.08  ? 175 THR C N   1 
ATOM   8447  C  CA  . THR D 1 175 ? -28.359 33.550  -78.438 1.00 25.45  ? 175 THR C CA  1 
ATOM   8448  C  C   . THR D 1 175 ? -27.109 34.368  -78.705 1.00 25.73  ? 175 THR C C   1 
ATOM   8449  O  O   . THR D 1 175 ? -26.886 35.416  -78.091 1.00 25.86  ? 175 THR C O   1 
ATOM   8450  C  CB  . THR D 1 175 ? -29.318 33.685  -79.628 1.00 27.37  ? 175 THR C CB  1 
ATOM   8451  O  OG1 . THR D 1 175 ? -29.537 35.084  -79.908 1.00 27.05  ? 175 THR C OG1 1 
ATOM   8452  C  CG2 . THR D 1 175 ? -30.669 32.973  -79.325 1.00 22.01  ? 175 THR C CG2 1 
ATOM   8453  N  N   . ASP D 1 176 ? -26.287 33.882  -79.639 1.00 24.88  ? 176 ASP C N   1 
ATOM   8454  C  CA  . ASP D 1 176 ? -25.329 34.766  -80.272 1.00 21.39  ? 176 ASP C CA  1 
ATOM   8455  C  C   . ASP D 1 176 ? -26.077 35.666  -81.252 1.00 27.32  ? 176 ASP C C   1 
ATOM   8456  O  O   . ASP D 1 176 ? -27.315 35.646  -81.332 1.00 20.07  ? 176 ASP C O   1 
ATOM   8457  C  CB  . ASP D 1 176 ? -24.207 33.976  -80.944 1.00 26.50  ? 176 ASP C CB  1 
ATOM   8458  C  CG  . ASP D 1 176 ? -24.695 33.024  -82.043 1.00 25.52  ? 176 ASP C CG  1 
ATOM   8459  O  OD1 . ASP D 1 176 ? -25.769 33.226  -82.652 1.00 23.44  ? 176 ASP C OD1 1 
ATOM   8460  O  OD2 . ASP D 1 176 ? -23.962 32.048  -82.311 1.00 29.47  ? 176 ASP C OD2 1 
ATOM   8461  N  N   . LEU D 1 177 ? -25.316 36.491  -82.002 1.00 27.22  ? 177 LEU C N   1 
ATOM   8462  C  CA  . LEU D 1 177 ? -25.947 37.424  -82.929 1.00 24.68  ? 177 LEU C CA  1 
ATOM   8463  C  C   . LEU D 1 177 ? -26.291 36.776  -84.276 1.00 28.57  ? 177 LEU C C   1 
ATOM   8464  O  O   . LEU D 1 177 ? -26.875 37.438  -85.140 1.00 28.44  ? 177 LEU C O   1 
ATOM   8465  C  CB  . LEU D 1 177 ? -25.051 38.657  -83.119 1.00 24.46  ? 177 LEU C CB  1 
ATOM   8466  C  CG  . LEU D 1 177 ? -25.290 39.836  -82.145 1.00 23.49  ? 177 LEU C CG  1 
ATOM   8467  C  CD1 . LEU D 1 177 ? -26.659 40.460  -82.364 1.00 24.62  ? 177 LEU C CD1 1 
ATOM   8468  C  CD2 . LEU D 1 177 ? -25.144 39.405  -80.684 1.00 20.05  ? 177 LEU C CD2 1 
ATOM   8469  N  N   . GLU D 1 178 ? -25.984 35.496  -84.470 1.00 27.61  ? 178 GLU C N   1 
ATOM   8470  C  CA  . GLU D 1 178 ? -26.531 34.754  -85.599 1.00 33.22  ? 178 GLU C CA  1 
ATOM   8471  C  C   . GLU D 1 178 ? -27.852 34.088  -85.249 1.00 29.84  ? 178 GLU C C   1 
ATOM   8472  O  O   . GLU D 1 178 ? -28.417 33.370  -86.086 1.00 26.89  ? 178 GLU C O   1 
ATOM   8473  C  CB  . GLU D 1 178 ? -25.549 33.679  -86.061 1.00 29.60  ? 178 GLU C CB  1 
ATOM   8474  C  CG  . GLU D 1 178 ? -24.089 34.082  -86.022 1.00 37.41  ? 178 GLU C CG  1 
ATOM   8475  C  CD  . GLU D 1 178 ? -23.512 34.243  -87.405 1.00 44.62  ? 178 GLU C CD  1 
ATOM   8476  O  OE1 . GLU D 1 178 ? -24.305 34.528  -88.322 1.00 50.67  ? 178 GLU C OE1 1 
ATOM   8477  O  OE2 . GLU D 1 178 ? -22.285 34.054  -87.584 1.00 45.11  ? 178 GLU C OE2 1 
ATOM   8478  N  N   . GLY D 1 179 ? -28.343 34.295  -84.031 1.00 26.14  ? 179 GLY C N   1 
ATOM   8479  C  CA  . GLY D 1 179 ? -29.610 33.742  -83.617 1.00 28.38  ? 179 GLY C CA  1 
ATOM   8480  C  C   . GLY D 1 179 ? -29.567 32.328  -83.082 1.00 26.77  ? 179 GLY C C   1 
ATOM   8481  O  O   . GLY D 1 179 ? -30.628 31.711  -82.944 1.00 27.85  ? 179 GLY C O   1 
ATOM   8482  N  N   . ASN D 1 180 ? -28.389 31.786  -82.798 1.00 24.83  ? 180 ASN C N   1 
ATOM   8483  C  CA  . ASN D 1 180 ? -28.254 30.430  -82.281 1.00 23.44  ? 180 ASN C CA  1 
ATOM   8484  C  C   . ASN D 1 180 ? -28.133 30.474  -80.771 1.00 20.91  ? 180 ASN C C   1 
ATOM   8485  O  O   . ASN D 1 180 ? -27.199 31.081  -80.241 1.00 22.84  ? 180 ASN C O   1 
ATOM   8486  C  CB  . ASN D 1 180 ? -27.035 29.752  -82.892 1.00 24.96  ? 180 ASN C CB  1 
ATOM   8487  C  CG  . ASN D 1 180 ? -27.097 29.748  -84.387 1.00 26.92  ? 180 ASN C CG  1 
ATOM   8488  O  OD1 . ASN D 1 180 ? -27.947 29.068  -84.980 1.00 23.56  ? 180 ASN C OD1 1 
ATOM   8489  N  ND2 . ASN D 1 180 ? -26.241 30.554  -85.017 1.00 22.67  ? 180 ASN C ND2 1 
ATOM   8490  N  N   . PHE D 1 181 ? -29.061 29.819  -80.085 1.00 20.35  ? 181 PHE C N   1 
ATOM   8491  C  CA  . PHE D 1 181 ? -29.023 29.792  -78.629 1.00 22.73  ? 181 PHE C CA  1 
ATOM   8492  C  C   . PHE D 1 181 ? -27.700 29.233  -78.134 1.00 19.46  ? 181 PHE C C   1 
ATOM   8493  O  O   . PHE D 1 181 ? -27.093 28.375  -78.769 1.00 22.30  ? 181 PHE C O   1 
ATOM   8494  C  CB  . PHE D 1 181 ? -30.174 28.942  -78.061 1.00 24.04  ? 181 PHE C CB  1 
ATOM   8495  C  CG  . PHE D 1 181 ? -31.365 29.743  -77.618 1.00 22.26  ? 181 PHE C CG  1 
ATOM   8496  C  CD1 . PHE D 1 181 ? -31.385 30.339  -76.373 1.00 23.00  ? 181 PHE C CD1 1 
ATOM   8497  C  CD2 . PHE D 1 181 ? -32.465 29.897  -78.439 1.00 23.45  ? 181 PHE C CD2 1 
ATOM   8498  C  CE1 . PHE D 1 181 ? -32.481 31.088  -75.958 1.00 23.97  ? 181 PHE C CE1 1 
ATOM   8499  C  CE2 . PHE D 1 181 ? -33.567 30.626  -78.018 1.00 24.30  ? 181 PHE C CE2 1 
ATOM   8500  C  CZ  . PHE D 1 181 ? -33.566 31.234  -76.784 1.00 24.51  ? 181 PHE C CZ  1 
ATOM   8501  N  N   . TYR D 1 182 ? -27.227 29.763  -77.010 1.00 19.76  ? 182 TYR C N   1 
ATOM   8502  C  CA  . TYR D 1 182 ? -26.255 29.042  -76.198 1.00 22.32  ? 182 TYR C CA  1 
ATOM   8503  C  C   . TYR D 1 182 ? -26.992 27.969  -75.406 1.00 24.35  ? 182 TYR C C   1 
ATOM   8504  O  O   . TYR D 1 182 ? -27.967 28.259  -74.710 1.00 23.38  ? 182 TYR C O   1 
ATOM   8505  C  CB  . TYR D 1 182 ? -25.509 29.983  -75.266 1.00 25.47  ? 182 TYR C CB  1 
ATOM   8506  C  CG  . TYR D 1 182 ? -24.569 30.920  -75.976 1.00 22.42  ? 182 TYR C CG  1 
ATOM   8507  C  CD1 . TYR D 1 182 ? -23.304 30.501  -76.378 1.00 23.40  ? 182 TYR C CD1 1 
ATOM   8508  C  CD2 . TYR D 1 182 ? -24.943 32.214  -76.244 1.00 22.97  ? 182 TYR C CD2 1 
ATOM   8509  C  CE1 . TYR D 1 182 ? -22.447 31.357  -77.027 1.00 24.35  ? 182 TYR C CE1 1 
ATOM   8510  C  CE2 . TYR D 1 182 ? -24.093 33.088  -76.884 1.00 22.65  ? 182 TYR C CE2 1 
ATOM   8511  C  CZ  . TYR D 1 182 ? -22.853 32.661  -77.280 1.00 23.45  ? 182 TYR C CZ  1 
ATOM   8512  O  OH  . TYR D 1 182 ? -22.040 33.555  -77.921 1.00 23.15  ? 182 TYR C OH  1 
ATOM   8513  N  N   . GLY D 1 183 ? -26.594 26.721  -75.582 1.00 30.61  ? 183 GLY C N   1 
ATOM   8514  C  CA  . GLY D 1 183 ? -27.154 25.632  -74.812 1.00 27.19  ? 183 GLY C CA  1 
ATOM   8515  C  C   . GLY D 1 183 ? -28.410 25.093  -75.447 1.00 30.41  ? 183 GLY C C   1 
ATOM   8516  O  O   . GLY D 1 183 ? -28.873 25.593  -76.476 1.00 34.87  ? 183 GLY C O   1 
ATOM   8517  N  N   . PRO D 1 184 ? -29.000 24.079  -74.825 1.00 33.18  ? 184 PRO C N   1 
ATOM   8518  C  CA  . PRO D 1 184 ? -30.139 23.358  -75.421 1.00 31.99  ? 184 PRO C CA  1 
ATOM   8519  C  C   . PRO D 1 184 ? -31.490 24.025  -75.181 1.00 33.58  ? 184 PRO C C   1 
ATOM   8520  O  O   . PRO D 1 184 ? -32.425 23.421  -74.654 1.00 39.96  ? 184 PRO C O   1 
ATOM   8521  C  CB  . PRO D 1 184 ? -30.050 21.987  -74.729 1.00 31.95  ? 184 PRO C CB  1 
ATOM   8522  C  CG  . PRO D 1 184 ? -29.537 22.317  -73.357 1.00 31.90  ? 184 PRO C CG  1 
ATOM   8523  C  CD  . PRO D 1 184 ? -28.614 23.525  -73.518 1.00 31.88  ? 184 PRO C CD  1 
ATOM   8524  N  N   . PHE D 1 185 ? -31.599 25.288  -75.568 1.00 30.67  ? 185 PHE C N   1 
ATOM   8525  C  CA  . PHE D 1 185 ? -32.803 26.050  -75.296 1.00 32.97  ? 185 PHE C CA  1 
ATOM   8526  C  C   . PHE D 1 185 ? -33.447 26.485  -76.606 1.00 34.95  ? 185 PHE C C   1 
ATOM   8527  O  O   . PHE D 1 185 ? -32.774 26.629  -77.636 1.00 34.72  ? 185 PHE C O   1 
ATOM   8528  C  CB  . PHE D 1 185 ? -32.488 27.269  -74.398 1.00 31.97  ? 185 PHE C CB  1 
ATOM   8529  C  CG  . PHE D 1 185 ? -31.679 26.911  -73.181 1.00 34.07  ? 185 PHE C CG  1 
ATOM   8530  C  CD1 . PHE D 1 185 ? -32.187 26.030  -72.229 1.00 33.52  ? 185 PHE C CD1 1 
ATOM   8531  C  CD2 . PHE D 1 185 ? -30.403 27.431  -73.003 1.00 31.27  ? 185 PHE C CD2 1 
ATOM   8532  C  CE1 . PHE D 1 185 ? -31.439 25.677  -71.112 1.00 32.81  ? 185 PHE C CE1 1 
ATOM   8533  C  CE2 . PHE D 1 185 ? -29.646 27.089  -71.893 1.00 30.83  ? 185 PHE C CE2 1 
ATOM   8534  C  CZ  . PHE D 1 185 ? -30.166 26.208  -70.944 1.00 31.62  ? 185 PHE C CZ  1 
ATOM   8535  N  N   . VAL D 1 186 ? -34.761 26.704  -76.547 1.00 34.93  ? 186 VAL C N   1 
ATOM   8536  C  CA  . VAL D 1 186 ? -35.560 27.163  -77.674 1.00 29.66  ? 186 VAL C CA  1 
ATOM   8537  C  C   . VAL D 1 186 ? -36.382 28.348  -77.201 1.00 31.51  ? 186 VAL C C   1 
ATOM   8538  O  O   . VAL D 1 186 ? -36.678 28.489  -76.012 1.00 28.50  ? 186 VAL C O   1 
ATOM   8539  C  CB  . VAL D 1 186 ? -36.484 26.059  -78.240 1.00 34.62  ? 186 VAL C CB  1 
ATOM   8540  C  CG1 . VAL D 1 186 ? -35.675 24.953  -78.889 1.00 28.11  ? 186 VAL C CG1 1 
ATOM   8541  C  CG2 . VAL D 1 186 ? -37.386 25.494  -77.129 1.00 33.63  ? 186 VAL C CG2 1 
ATOM   8542  N  N   . ASP D 1 187 ? -36.751 29.209  -78.142 1.00 34.79  ? 187 ASP C N   1 
ATOM   8543  C  CA  . ASP D 1 187 ? -37.495 30.420  -77.801 1.00 34.43  ? 187 ASP C CA  1 
ATOM   8544  C  C   . ASP D 1 187 ? -38.994 30.125  -77.841 1.00 34.25  ? 187 ASP C C   1 
ATOM   8545  O  O   . ASP D 1 187 ? -39.751 30.594  -78.695 1.00 30.83  ? 187 ASP C O   1 
ATOM   8546  C  CB  . ASP D 1 187 ? -37.100 31.568  -78.719 1.00 33.83  ? 187 ASP C CB  1 
ATOM   8547  C  CG  . ASP D 1 187 ? -37.187 31.202  -80.168 1.00 32.37  ? 187 ASP C CG  1 
ATOM   8548  O  OD1 . ASP D 1 187 ? -37.474 30.020  -80.460 1.00 34.74  ? 187 ASP C OD1 1 
ATOM   8549  O  OD2 . ASP D 1 187 ? -36.982 32.103  -81.008 1.00 36.89  ? 187 ASP C OD2 1 
ATOM   8550  N  N   . ARG D 1 188 ? -39.406 29.290  -76.891 1.00 34.30  ? 188 ARG C N   1 
ATOM   8551  C  CA  . ARG D 1 188 ? -40.807 28.978  -76.681 1.00 39.73  ? 188 ARG C CA  1 
ATOM   8552  C  C   . ARG D 1 188 ? -41.103 29.060  -75.197 1.00 43.00  ? 188 ARG C C   1 
ATOM   8553  O  O   . ARG D 1 188 ? -40.205 28.991  -74.357 1.00 40.85  ? 188 ARG C O   1 
ATOM   8554  C  CB  . ARG D 1 188 ? -41.184 27.582  -77.188 1.00 41.55  ? 188 ARG C CB  1 
ATOM   8555  C  CG  . ARG D 1 188 ? -40.760 27.309  -78.605 1.00 48.24  ? 188 ARG C CG  1 
ATOM   8556  C  CD  . ARG D 1 188 ? -41.518 26.143  -79.186 1.00 51.08  ? 188 ARG C CD  1 
ATOM   8557  N  NE  . ARG D 1 188 ? -41.025 24.865  -78.692 1.00 62.33  ? 188 ARG C NE  1 
ATOM   8558  C  CZ  . ARG D 1 188 ? -40.142 24.107  -79.326 1.00 57.87  ? 188 ARG C CZ  1 
ATOM   8559  N  NH1 . ARG D 1 188 ? -39.594 24.496  -80.469 1.00 52.73  ? 188 ARG C NH1 1 
ATOM   8560  N  NH2 . ARG D 1 188 ? -39.802 22.930  -78.803 1.00 49.66  ? 188 ARG C NH2 1 
ATOM   8561  N  N   . GLN D 1 189 ? -42.387 29.192  -74.886 1.00 48.58  ? 189 GLN C N   1 
ATOM   8562  C  CA  . GLN D 1 189 ? -42.854 29.184  -73.503 1.00 46.86  ? 189 GLN C CA  1 
ATOM   8563  C  C   . GLN D 1 189 ? -43.262 27.752  -73.148 1.00 43.36  ? 189 GLN C C   1 
ATOM   8564  O  O   . GLN D 1 189 ? -44.441 27.395  -73.087 1.00 49.12  ? 189 GLN C O   1 
ATOM   8565  C  CB  . GLN D 1 189 ? -43.998 30.184  -73.340 1.00 44.32  ? 189 GLN C CB  1 
ATOM   8566  C  CG  . GLN D 1 189 ? -44.559 30.370  -71.946 1.00 40.09  ? 189 GLN C CG  1 
ATOM   8567  C  CD  . GLN D 1 189 ? -45.459 31.597  -71.864 1.00 43.42  ? 189 GLN C CD  1 
ATOM   8568  O  OE1 . GLN D 1 189 ? -45.539 32.381  -72.811 1.00 46.63  ? 189 GLN C OE1 1 
ATOM   8569  N  NE2 . GLN D 1 189 ? -46.156 31.756  -70.743 1.00 35.55  ? 189 GLN C NE2 1 
ATOM   8570  N  N   . THR D 1 190 ? -42.235 26.920  -72.942 1.00 44.29  ? 190 THR C N   1 
ATOM   8571  C  CA  . THR D 1 190 ? -42.351 25.519  -72.541 1.00 39.68  ? 190 THR C CA  1 
ATOM   8572  C  C   . THR D 1 190 ? -41.376 25.248  -71.400 1.00 36.13  ? 190 THR C C   1 
ATOM   8573  O  O   . THR D 1 190 ? -40.475 26.041  -71.130 1.00 34.83  ? 190 THR C O   1 
ATOM   8574  C  CB  . THR D 1 190 ? -42.068 24.554  -73.711 1.00 35.27  ? 190 THR C CB  1 
ATOM   8575  O  OG1 . THR D 1 190 ? -40.706 24.711  -74.138 1.00 35.66  ? 190 THR C OG1 1 
ATOM   8576  C  CG2 . THR D 1 190 ? -43.021 24.792  -74.893 1.00 36.47  ? 190 THR C CG2 1 
ATOM   8577  N  N   . ALA D 1 191 ? -41.553 24.103  -70.734 1.00 33.97  ? 191 ALA C N   1 
ATOM   8578  C  CA  . ALA D 1 191 ? -40.702 23.705  -69.612 1.00 35.61  ? 191 ALA C CA  1 
ATOM   8579  C  C   . ALA D 1 191 ? -39.306 23.341  -70.107 1.00 37.34  ? 191 ALA C C   1 
ATOM   8580  O  O   . ALA D 1 191 ? -39.130 22.356  -70.828 1.00 45.79  ? 191 ALA C O   1 
ATOM   8581  C  CB  . ALA D 1 191 ? -41.331 22.530  -68.862 1.00 35.14  ? 191 ALA C CB  1 
ATOM   8582  N  N   . GLN D 1 192 ? -38.310 24.131  -69.721 1.00 37.11  ? 192 GLN C N   1 
ATOM   8583  C  CA  . GLN D 1 192 ? -36.914 23.906  -70.077 1.00 37.42  ? 192 GLN C CA  1 
ATOM   8584  C  C   . GLN D 1 192 ? -36.084 24.003  -68.812 1.00 44.89  ? 192 GLN C C   1 
ATOM   8585  O  O   . GLN D 1 192 ? -36.352 24.853  -67.961 1.00 45.23  ? 192 GLN C O   1 
ATOM   8586  C  CB  . GLN D 1 192 ? -36.403 24.929  -71.106 1.00 37.87  ? 192 GLN C CB  1 
ATOM   8587  C  CG  . GLN D 1 192 ? -37.308 25.131  -72.290 1.00 33.34  ? 192 GLN C CG  1 
ATOM   8588  C  CD  . GLN D 1 192 ? -36.722 26.076  -73.290 1.00 36.74  ? 192 GLN C CD  1 
ATOM   8589  O  OE1 . GLN D 1 192 ? -35.609 25.874  -73.763 1.00 34.71  ? 192 GLN C OE1 1 
ATOM   8590  N  NE2 . GLN D 1 192 ? -37.464 27.131  -73.620 1.00 38.06  ? 192 GLN C NE2 1 
ATOM   8591  N  N   . ALA D 1 193 ? -35.085 23.134  -68.679 1.00 39.75  ? 193 ALA C N   1 
ATOM   8592  C  CA  . ALA D 1 193 ? -34.241 23.120  -67.495 1.00 37.43  ? 193 ALA C CA  1 
ATOM   8593  C  C   . ALA D 1 193 ? -32.808 23.481  -67.858 1.00 41.07  ? 193 ALA C C   1 
ATOM   8594  O  O   . ALA D 1 193 ? -32.274 23.025  -68.873 1.00 37.70  ? 193 ALA C O   1 
ATOM   8595  C  CB  . ALA D 1 193 ? -34.270 21.757  -66.806 1.00 36.88  ? 193 ALA C CB  1 
ATOM   8596  N  N   . ALA D 1 194 ? -32.200 24.308  -67.008 1.00 39.04  ? 194 ALA C N   1 
ATOM   8597  C  CA  . ALA D 1 194 ? -30.841 24.776  -67.240 1.00 31.81  ? 194 ALA C CA  1 
ATOM   8598  C  C   . ALA D 1 194 ? -29.875 23.618  -67.431 1.00 45.32  ? 194 ALA C C   1 
ATOM   8599  O  O   . ALA D 1 194 ? -29.143 23.558  -68.426 1.00 55.94  ? 194 ALA C O   1 
ATOM   8600  C  CB  . ALA D 1 194 ? -30.390 25.644  -66.069 1.00 36.62  ? 194 ALA C CB  1 
ATOM   8601  N  N   . GLY D 1 195 ? -29.836 22.705  -66.474 1.00 41.44  ? 195 GLY C N   1 
ATOM   8602  C  CA  . GLY D 1 195 ? -28.757 21.747  -66.370 1.00 39.69  ? 195 GLY C CA  1 
ATOM   8603  C  C   . GLY D 1 195 ? -27.891 22.042  -65.159 1.00 42.15  ? 195 GLY C C   1 
ATOM   8604  O  O   . GLY D 1 195 ? -28.021 23.066  -64.492 1.00 43.89  ? 195 GLY C O   1 
ATOM   8605  N  N   . THR D 1 196 ? -27.023 21.095  -64.839 1.00 43.23  ? 196 THR C N   1 
ATOM   8606  C  CA  . THR D 1 196 ? -26.200 21.251  -63.651 1.00 45.45  ? 196 THR C CA  1 
ATOM   8607  C  C   . THR D 1 196 ? -24.967 22.100  -63.958 1.00 37.46  ? 196 THR C C   1 
ATOM   8608  O  O   . THR D 1 196 ? -24.415 22.062  -65.062 1.00 44.35  ? 196 THR C O   1 
ATOM   8609  C  CB  . THR D 1 196 ? -25.807 19.888  -63.085 1.00 51.80  ? 196 THR C CB  1 
ATOM   8610  O  OG1 . THR D 1 196 ? -25.156 20.076  -61.820 1.00 48.34  ? 196 THR C OG1 1 
ATOM   8611  C  CG2 . THR D 1 196 ? -24.902 19.125  -64.062 1.00 43.95  ? 196 THR C CG2 1 
ATOM   8612  N  N   . ASP D 1 197 ? -24.597 22.935  -63.008 1.00 37.78  ? 197 ASP C N   1 
ATOM   8613  C  CA  . ASP D 1 197 ? -23.500 23.891  -63.296 1.00 38.30  ? 197 ASP C CA  1 
ATOM   8614  C  C   . ASP D 1 197 ? -22.267 23.580  -62.456 1.00 40.14  ? 197 ASP C C   1 
ATOM   8615  O  O   . ASP D 1 197 ? -22.358 22.796  -61.506 1.00 43.51  ? 197 ASP C O   1 
ATOM   8616  C  CB  . ASP D 1 197 ? -23.965 25.340  -63.123 1.00 33.90  ? 197 ASP C CB  1 
ATOM   8617  C  CG  . ASP D 1 197 ? -23.000 26.385  -63.655 1.00 38.28  ? 197 ASP C CG  1 
ATOM   8618  O  OD1 . ASP D 1 197 ? -22.275 26.084  -64.624 1.00 33.35  ? 197 ASP C OD1 1 
ATOM   8619  O  OD2 . ASP D 1 197 ? -22.987 27.494  -63.092 1.00 32.93  ? 197 ASP C OD2 1 
ATOM   8620  N  N   . THR D 1 198 ? -21.155 24.171  -62.842 1.00 35.41  ? 198 THR C N   1 
ATOM   8621  C  CA  . THR D 1 198 ? -19.882 23.924  -62.159 1.00 32.31  ? 198 THR C CA  1 
ATOM   8622  C  C   . THR D 1 198 ? -19.218 25.245  -61.838 1.00 28.90  ? 198 THR C C   1 
ATOM   8623  O  O   . THR D 1 198 ? -19.512 26.229  -62.505 1.00 30.17  ? 198 THR C O   1 
ATOM   8624  C  CB  . THR D 1 198 ? -18.914 23.165  -63.071 1.00 32.92  ? 198 THR C CB  1 
ATOM   8625  O  OG1 . THR D 1 198 ? -19.383 23.233  -64.416 1.00 41.45  ? 198 THR C OG1 1 
ATOM   8626  C  CG2 . THR D 1 198 ? -18.746 21.717  -62.666 1.00 33.55  ? 198 THR C CG2 1 
ATOM   8627  N  N   . THR D 1 199 ? -18.380 25.248  -60.820 1.00 26.68  ? 199 THR C N   1 
ATOM   8628  C  CA  . THR D 1 199 ? -17.571 26.424  -60.574 1.00 30.36  ? 199 THR C CA  1 
ATOM   8629  C  C   . THR D 1 199 ? -16.393 26.459  -61.546 1.00 31.14  ? 199 THR C C   1 
ATOM   8630  O  O   . THR D 1 199 ? -15.714 25.448  -61.761 1.00 31.86  ? 199 THR C O   1 
ATOM   8631  C  CB  . THR D 1 199 ? -17.075 26.427  -59.126 1.00 28.36  ? 199 THR C CB  1 
ATOM   8632  O  OG1 . THR D 1 199 ? -18.199 26.461  -58.236 1.00 22.64  ? 199 THR C OG1 1 
ATOM   8633  C  CG2 . THR D 1 199 ? -16.156 27.623  -58.878 1.00 27.08  ? 199 THR C CG2 1 
ATOM   8634  N  N   . ILE D 1 200 ? -16.207 27.607  -62.192 1.00 28.69  ? 200 ILE C N   1 
ATOM   8635  C  CA  . ILE D 1 200 ? -15.103 27.762  -63.177 1.00 23.80  ? 200 ILE C CA  1 
ATOM   8636  C  C   . ILE D 1 200 ? -13.802 27.807  -62.384 1.00 29.39  ? 200 ILE C C   1 
ATOM   8637  O  O   . ILE D 1 200 ? -13.429 28.890  -61.909 1.00 27.55  ? 200 ILE C O   1 
ATOM   8638  C  CB  . ILE D 1 200 ? -15.353 28.983  -64.085 1.00 27.71  ? 200 ILE C CB  1 
ATOM   8639  C  CG1 . ILE D 1 200 ? -16.796 29.019  -64.593 1.00 24.93  ? 200 ILE C CG1 1 
ATOM   8640  C  CG2 . ILE D 1 200 ? -14.348 29.036  -65.225 1.00 30.18  ? 200 ILE C CG2 1 
ATOM   8641  C  CD1 . ILE D 1 200 ? -17.331 30.406  -64.832 1.00 20.39  ? 200 ILE C CD1 1 
ATOM   8642  N  N   . THR D 1 201 ? -13.140 26.660  -62.262 1.00 27.91  ? 201 THR C N   1 
ATOM   8643  C  CA  . THR D 1 201 ? -11.943 26.553  -61.429 1.00 20.77  ? 201 THR C CA  1 
ATOM   8644  C  C   . THR D 1 201 ? -10.845 27.499  -61.896 1.00 22.41  ? 201 THR C C   1 
ATOM   8645  O  O   . THR D 1 201 ? -10.217 28.182  -61.075 1.00 25.15  ? 201 THR C O   1 
ATOM   8646  C  CB  . THR D 1 201 ? -11.406 25.119  -61.426 1.00 25.02  ? 201 THR C CB  1 
ATOM   8647  O  OG1 . THR D 1 201 ? -12.484 24.180  -61.272 1.00 25.29  ? 201 THR C OG1 1 
ATOM   8648  C  CG2 . THR D 1 201 ? -10.388 24.954  -60.279 1.00 26.05  ? 201 THR C CG2 1 
ATOM   8649  N  N   . VAL D 1 202 ? -10.601 27.563  -63.209 1.00 24.39  ? 202 VAL C N   1 
ATOM   8650  C  CA  . VAL D 1 202 ? -9.519  28.416  -63.705 1.00 24.47  ? 202 VAL C CA  1 
ATOM   8651  C  C   . VAL D 1 202 ? -9.756  29.871  -63.321 1.00 23.70  ? 202 VAL C C   1 
ATOM   8652  O  O   . VAL D 1 202 ? -8.796  30.616  -63.093 1.00 25.64  ? 202 VAL C O   1 
ATOM   8653  C  CB  . VAL D 1 202 ? -9.362  28.289  -65.235 1.00 22.61  ? 202 VAL C CB  1 
ATOM   8654  C  CG1 . VAL D 1 202 ? -10.599 28.875  -65.968 1.00 19.39  ? 202 VAL C CG1 1 
ATOM   8655  C  CG2 . VAL D 1 202 ? -8.060  28.933  -65.699 1.00 19.48  ? 202 VAL C CG2 1 
ATOM   8656  N  N   . ASN D 1 203 ? -11.028 30.301  -63.252 1.00 23.25  ? 203 ASN C N   1 
ATOM   8657  C  CA  . ASN D 1 203 ? -11.343 31.677  -62.866 1.00 21.59  ? 203 ASN C CA  1 
ATOM   8658  C  C   . ASN D 1 203 ? -11.112 31.924  -61.376 1.00 21.33  ? 203 ASN C C   1 
ATOM   8659  O  O   . ASN D 1 203 ? -10.740 33.041  -60.976 1.00 22.09  ? 203 ASN C O   1 
ATOM   8660  C  CB  . ASN D 1 203 ? -12.784 32.022  -63.254 1.00 21.13  ? 203 ASN C CB  1 
ATOM   8661  C  CG  . ASN D 1 203 ? -12.951 32.278  -64.742 1.00 26.00  ? 203 ASN C CG  1 
ATOM   8662  O  OD1 . ASN D 1 203 ? -11.977 32.248  -65.504 1.00 27.10  ? 203 ASN C OD1 1 
ATOM   8663  N  ND2 . ASN D 1 203 ? -14.185 32.581  -65.165 1.00 27.16  ? 203 ASN C ND2 1 
ATOM   8664  N  N   . VAL D 1 204 ? -11.382 30.923  -60.533 1.00 21.97  ? 204 VAL C N   1 
ATOM   8665  C  CA  . VAL D 1 204 ? -11.121 31.057  -59.101 1.00 18.06  ? 204 VAL C CA  1 
ATOM   8666  C  C   . VAL D 1 204 ? -9.641  31.290  -58.861 1.00 20.72  ? 204 VAL C C   1 
ATOM   8667  O  O   . VAL D 1 204 ? -9.244  32.153  -58.062 1.00 20.75  ? 204 VAL C O   1 
ATOM   8668  C  CB  . VAL D 1 204 ? -11.611 29.815  -58.337 1.00 18.75  ? 204 VAL C CB  1 
ATOM   8669  C  CG1 . VAL D 1 204 ? -11.200 29.913  -56.886 1.00 21.91  ? 204 VAL C CG1 1 
ATOM   8670  C  CG2 . VAL D 1 204 ? -13.105 29.690  -58.431 1.00 18.75  ? 204 VAL C CG2 1 
ATOM   8671  N  N   . LEU D 1 205 ? -8.805  30.493  -59.531 1.00 22.96  ? 205 LEU C N   1 
ATOM   8672  C  CA  . LEU D 1 205 ? -7.359  30.608  -59.391 1.00 20.09  ? 205 LEU C CA  1 
ATOM   8673  C  C   . LEU D 1 205 ? -6.872  31.980  -59.839 1.00 18.99  ? 205 LEU C C   1 
ATOM   8674  O  O   . LEU D 1 205 ? -6.019  32.585  -59.182 1.00 17.32  ? 205 LEU C O   1 
ATOM   8675  C  CB  . LEU D 1 205 ? -6.686  29.493  -60.187 1.00 18.35  ? 205 LEU C CB  1 
ATOM   8676  C  CG  . LEU D 1 205 ? -6.911  28.096  -59.599 1.00 20.63  ? 205 LEU C CG  1 
ATOM   8677  C  CD1 . LEU D 1 205 ? -6.594  27.051  -60.627 1.00 20.04  ? 205 LEU C CD1 1 
ATOM   8678  C  CD2 . LEU D 1 205 ? -6.065  27.899  -58.363 1.00 17.72  ? 205 LEU C CD2 1 
ATOM   8679  N  N   . ALA D 1 206 ? -7.396  32.474  -60.969 1.00 18.37  ? 206 ALA C N   1 
ATOM   8680  C  CA  . ALA D 1 206 ? -7.065  33.820  -61.422 1.00 21.25  ? 206 ALA C CA  1 
ATOM   8681  C  C   . ALA D 1 206 ? -7.412  34.849  -60.364 1.00 19.85  ? 206 ALA C C   1 
ATOM   8682  O  O   . ALA D 1 206 ? -6.632  35.772  -60.102 1.00 28.97  ? 206 ALA C O   1 
ATOM   8683  C  CB  . ALA D 1 206 ? -7.800  34.129  -62.722 1.00 23.29  ? 206 ALA C CB  1 
ATOM   8684  N  N   . TRP D 1 207 ? -8.555  34.680  -59.706 1.00 22.39  ? 207 TRP C N   1 
ATOM   8685  C  CA  . TRP D 1 207 ? -8.997  35.680  -58.740 1.00 21.53  ? 207 TRP C CA  1 
ATOM   8686  C  C   . TRP D 1 207 ? -8.141  35.636  -57.492 1.00 20.62  ? 207 TRP C C   1 
ATOM   8687  O  O   . TRP D 1 207 ? -7.816  36.681  -56.915 1.00 21.29  ? 207 TRP C O   1 
ATOM   8688  C  CB  . TRP D 1 207 ? -10.469 35.442  -58.422 1.00 24.01  ? 207 TRP C CB  1 
ATOM   8689  C  CG  . TRP D 1 207 ? -11.038 36.183  -57.296 1.00 21.75  ? 207 TRP C CG  1 
ATOM   8690  C  CD1 . TRP D 1 207 ? -11.439 37.488  -57.300 1.00 28.28  ? 207 TRP C CD1 1 
ATOM   8691  C  CD2 . TRP D 1 207 ? -11.391 35.655  -56.021 1.00 20.56  ? 207 TRP C CD2 1 
ATOM   8692  N  NE1 . TRP D 1 207 ? -11.982 37.815  -56.082 1.00 27.65  ? 207 TRP C NE1 1 
ATOM   8693  C  CE2 . TRP D 1 207 ? -11.965 36.705  -55.280 1.00 21.13  ? 207 TRP C CE2 1 
ATOM   8694  C  CE3 . TRP D 1 207 ? -11.254 34.396  -55.418 1.00 25.54  ? 207 TRP C CE3 1 
ATOM   8695  C  CZ2 . TRP D 1 207 ? -12.398 36.545  -53.967 1.00 26.77  ? 207 TRP C CZ2 1 
ATOM   8696  C  CZ3 . TRP D 1 207 ? -11.690 34.229  -54.120 1.00 25.51  ? 207 TRP C CZ3 1 
ATOM   8697  C  CH2 . TRP D 1 207 ? -12.259 35.299  -53.401 1.00 28.38  ? 207 TRP C CH2 1 
ATOM   8698  N  N   . LEU D 1 208 ? -7.714  34.432  -57.097 1.00 25.51  ? 208 LEU C N   1 
ATOM   8699  C  CA  . LEU D 1 208 ? -6.741  34.313  -56.016 1.00 23.57  ? 208 LEU C CA  1 
ATOM   8700  C  C   . LEU D 1 208 ? -5.452  35.055  -56.372 1.00 27.12  ? 208 LEU C C   1 
ATOM   8701  O  O   . LEU D 1 208 ? -4.895  35.769  -55.531 1.00 25.95  ? 208 LEU C O   1 
ATOM   8702  C  CB  . LEU D 1 208 ? -6.462  32.833  -55.729 1.00 25.56  ? 208 LEU C CB  1 
ATOM   8703  C  CG  . LEU D 1 208 ? -7.643  32.067  -55.118 1.00 23.20  ? 208 LEU C CG  1 
ATOM   8704  C  CD1 . LEU D 1 208 ? -7.334  30.595  -55.099 1.00 19.95  ? 208 LEU C CD1 1 
ATOM   8705  C  CD2 . LEU D 1 208 ? -7.984  32.579  -53.703 1.00 18.86  ? 208 LEU C CD2 1 
ATOM   8706  N  N   . TYR D 1 209 ? -5.015  34.968  -57.642 1.00 22.43  ? 209 TYR C N   1 
ATOM   8707  C  CA  . TYR D 1 209 ? -3.843  35.725  -58.083 1.00 23.23  ? 209 TYR C CA  1 
ATOM   8708  C  C   . TYR D 1 209 ? -4.094  37.230  -58.006 1.00 28.05  ? 209 TYR C C   1 
ATOM   8709  O  O   . TYR D 1 209 ? -3.233  37.988  -57.542 1.00 24.19  ? 209 TYR C O   1 
ATOM   8710  C  CB  . TYR D 1 209 ? -3.450  35.310  -59.505 1.00 22.55  ? 209 TYR C CB  1 
ATOM   8711  C  CG  . TYR D 1 209 ? -2.549  34.095  -59.564 1.00 26.31  ? 209 TYR C CG  1 
ATOM   8712  C  CD1 . TYR D 1 209 ? -1.240  34.165  -59.109 1.00 26.62  ? 209 TYR C CD1 1 
ATOM   8713  C  CD2 . TYR D 1 209 ? -3.007  32.878  -60.059 1.00 27.60  ? 209 TYR C CD2 1 
ATOM   8714  C  CE1 . TYR D 1 209 ? -0.407  33.064  -59.147 1.00 30.77  ? 209 TYR C CE1 1 
ATOM   8715  C  CE2 . TYR D 1 209 ? -2.179  31.771  -60.101 1.00 27.74  ? 209 TYR C CE2 1 
ATOM   8716  C  CZ  . TYR D 1 209 ? -0.875  31.872  -59.643 1.00 31.45  ? 209 TYR C CZ  1 
ATOM   8717  O  OH  . TYR D 1 209 ? -0.031  30.776  -59.662 1.00 33.38  ? 209 TYR C OH  1 
ATOM   8718  N  N   . ALA D 1 210 ? -5.269  37.679  -58.461 1.00 27.38  ? 210 ALA C N   1 
ATOM   8719  C  CA  . ALA D 1 210 ? -5.667  39.068  -58.256 1.00 25.66  ? 210 ALA C CA  1 
ATOM   8720  C  C   . ALA D 1 210 ? -5.590  39.453  -56.785 1.00 25.99  ? 210 ALA C C   1 
ATOM   8721  O  O   . ALA D 1 210 ? -5.220  40.580  -56.459 1.00 28.69  ? 210 ALA C O   1 
ATOM   8722  C  CB  . ALA D 1 210 ? -7.074  39.312  -58.801 1.00 21.88  ? 210 ALA C CB  1 
ATOM   8723  N  N   . ALA D 1 211 ? -5.953  38.541  -55.877 1.00 29.96  ? 211 ALA C N   1 
ATOM   8724  C  CA  . ALA D 1 211 ? -5.882  38.870  -54.451 1.00 30.67  ? 211 ALA C CA  1 
ATOM   8725  C  C   . ALA D 1 211 ? -4.446  39.151  -54.013 1.00 30.83  ? 211 ALA C C   1 
ATOM   8726  O  O   . ALA D 1 211 ? -4.167  40.173  -53.370 1.00 28.07  ? 211 ALA C O   1 
ATOM   8727  C  CB  . ALA D 1 211 ? -6.484  37.743  -53.614 1.00 25.01  ? 211 ALA C CB  1 
ATOM   8728  N  N   . VAL D 1 212 ? -3.516  38.259  -54.378 1.00 28.00  ? 212 VAL C N   1 
ATOM   8729  C  CA  . VAL D 1 212 ? -2.104  38.438  -54.030 1.00 30.38  ? 212 VAL C CA  1 
ATOM   8730  C  C   . VAL D 1 212 ? -1.552  39.719  -54.645 1.00 26.61  ? 212 VAL C C   1 
ATOM   8731  O  O   . VAL D 1 212 ? -0.830  40.478  -53.989 1.00 29.21  ? 212 VAL C O   1 
ATOM   8732  C  CB  . VAL D 1 212 ? -1.291  37.197  -54.445 1.00 27.30  ? 212 VAL C CB  1 
ATOM   8733  C  CG1 . VAL D 1 212 ? 0.191   37.471  -54.336 1.00 24.59  ? 212 VAL C CG1 1 
ATOM   8734  C  CG2 . VAL D 1 212 ? -1.647  36.058  -53.552 1.00 30.59  ? 212 VAL C CG2 1 
ATOM   8735  N  N   . ILE D 1 213 ? -1.858  39.969  -55.915 1.00 24.36  ? 213 ILE C N   1 
ATOM   8736  C  CA  . ILE D 1 213 ? -1.444  41.227  -56.538 1.00 30.75  ? 213 ILE C CA  1 
ATOM   8737  C  C   . ILE D 1 213 ? -1.914  42.413  -55.699 1.00 30.33  ? 213 ILE C C   1 
ATOM   8738  O  O   . ILE D 1 213 ? -1.217  43.430  -55.604 1.00 34.23  ? 213 ILE C O   1 
ATOM   8739  C  CB  . ILE D 1 213 ? -1.981  41.301  -57.992 1.00 28.80  ? 213 ILE C CB  1 
ATOM   8740  C  CG1 . ILE D 1 213 ? -1.295  40.262  -58.884 1.00 27.16  ? 213 ILE C CG1 1 
ATOM   8741  C  CG2 . ILE D 1 213 ? -1.758  42.685  -58.597 1.00 30.79  ? 213 ILE C CG2 1 
ATOM   8742  C  CD1 . ILE D 1 213 ? -2.034  40.006  -60.171 1.00 26.01  ? 213 ILE C CD1 1 
ATOM   8743  N  N   . ASN D 1 214 ? -3.079  42.292  -55.048 1.00 29.79  ? 214 ASN C N   1 
ATOM   8744  C  CA  . ASN D 1 214 ? -3.678  43.362  -54.250 1.00 31.32  ? 214 ASN C CA  1 
ATOM   8745  C  C   . ASN D 1 214 ? -3.440  43.230  -52.740 1.00 33.14  ? 214 ASN C C   1 
ATOM   8746  O  O   . ASN D 1 214 ? -4.204  43.801  -51.956 1.00 35.45  ? 214 ASN C O   1 
ATOM   8747  C  CB  . ASN D 1 214 ? -5.176  43.476  -54.544 1.00 28.21  ? 214 ASN C CB  1 
ATOM   8748  C  CG  . ASN D 1 214 ? -5.450  44.195  -55.847 1.00 37.19  ? 214 ASN C CG  1 
ATOM   8749  O  OD1 . ASN D 1 214 ? -5.586  43.556  -56.908 1.00 34.24  ? 214 ASN C OD1 1 
ATOM   8750  N  ND2 . ASN D 1 214 ? -5.585  45.524  -55.779 1.00 36.64  ? 214 ASN C ND2 1 
ATOM   8751  N  N   . GLY D 1 215 ? -2.464  42.431  -52.305 1.00 34.28  ? 215 GLY C N   1 
ATOM   8752  C  CA  . GLY D 1 215 ? -2.076  42.443  -50.909 1.00 28.37  ? 215 GLY C CA  1 
ATOM   8753  C  C   . GLY D 1 215 ? -2.794  41.474  -49.987 1.00 38.77  ? 215 GLY C C   1 
ATOM   8754  O  O   . GLY D 1 215 ? -2.477  41.458  -48.789 1.00 40.96  ? 215 GLY C O   1 
ATOM   8755  N  N   . ASP D 1 216 ? -3.785  40.718  -50.491 1.00 40.12  ? 216 ASP C N   1 
ATOM   8756  C  CA  . ASP D 1 216 ? -4.468  39.646  -49.756 1.00 34.55  ? 216 ASP C CA  1 
ATOM   8757  C  C   . ASP D 1 216 ? -3.693  38.342  -49.912 1.00 37.37  ? 216 ASP C C   1 
ATOM   8758  O  O   . ASP D 1 216 ? -3.717  37.727  -50.983 1.00 37.43  ? 216 ASP C O   1 
ATOM   8759  C  CB  . ASP D 1 216 ? -5.896  39.458  -50.266 1.00 42.77  ? 216 ASP C CB  1 
ATOM   8760  C  CG  . ASP D 1 216 ? -6.926  40.250  -49.490 1.00 36.43  ? 216 ASP C CG  1 
ATOM   8761  O  OD1 . ASP D 1 216 ? -6.605  40.830  -48.437 1.00 43.52  ? 216 ASP C OD1 1 
ATOM   8762  O  OD2 . ASP D 1 216 ? -8.082  40.287  -49.954 1.00 38.64  ? 216 ASP C OD2 1 
ATOM   8763  N  N   . ARG D 1 217 ? -3.060  37.893  -48.824 1.00 40.02  ? 217 ARG C N   1 
ATOM   8764  C  CA  . ARG D 1 217 ? -2.139  36.761  -48.828 1.00 37.67  ? 217 ARG C CA  1 
ATOM   8765  C  C   . ARG D 1 217 ? -2.424  35.741  -47.727 1.00 38.70  ? 217 ARG C C   1 
ATOM   8766  O  O   . ARG D 1 217 ? -1.696  34.745  -47.640 1.00 43.20  ? 217 ARG C O   1 
ATOM   8767  C  CB  . ARG D 1 217 ? -0.682  37.232  -48.667 1.00 40.06  ? 217 ARG C CB  1 
ATOM   8768  C  CG  . ARG D 1 217 ? -0.193  38.167  -49.742 1.00 43.67  ? 217 ARG C CG  1 
ATOM   8769  C  CD  . ARG D 1 217 ? 1.249   38.634  -49.501 1.00 41.73  ? 217 ARG C CD  1 
ATOM   8770  N  NE  . ARG D 1 217 ? 1.712   39.349  -50.687 1.00 44.22  ? 217 ARG C NE  1 
ATOM   8771  C  CZ  . ARG D 1 217 ? 2.346   38.810  -51.721 1.00 39.19  ? 217 ARG C CZ  1 
ATOM   8772  N  NH1 . ARG D 1 217 ? 2.722   37.543  -51.723 1.00 38.24  ? 217 ARG C NH1 1 
ATOM   8773  N  NH2 . ARG D 1 217 ? 2.554   39.549  -52.806 1.00 43.32  ? 217 ARG C NH2 1 
ATOM   8774  N  N   . TRP D 1 218 ? -3.414  35.968  -46.852 1.00 26.40  ? 218 TRP C N   1 
ATOM   8775  C  CA  . TRP D 1 218 ? -3.553  35.074  -45.703 1.00 34.24  ? 218 TRP C CA  1 
ATOM   8776  C  C   . TRP D 1 218 ? -3.767  33.622  -46.113 1.00 37.28  ? 218 TRP C C   1 
ATOM   8777  O  O   . TRP D 1 218 ? -3.452  32.714  -45.337 1.00 41.12  ? 218 TRP C O   1 
ATOM   8778  C  CB  . TRP D 1 218 ? -4.714  35.497  -44.786 1.00 34.81  ? 218 TRP C CB  1 
ATOM   8779  C  CG  . TRP D 1 218 ? -6.059  35.534  -45.440 1.00 39.26  ? 218 TRP C CG  1 
ATOM   8780  C  CD1 . TRP D 1 218 ? -6.673  36.636  -45.977 1.00 38.88  ? 218 TRP C CD1 1 
ATOM   8781  C  CD2 . TRP D 1 218 ? -6.972  34.432  -45.634 1.00 36.08  ? 218 TRP C CD2 1 
ATOM   8782  N  NE1 . TRP D 1 218 ? -7.903  36.291  -46.486 1.00 36.57  ? 218 TRP C NE1 1 
ATOM   8783  C  CE2 . TRP D 1 218 ? -8.112  34.951  -46.289 1.00 33.62  ? 218 TRP C CE2 1 
ATOM   8784  C  CE3 . TRP D 1 218 ? -6.936  33.061  -45.324 1.00 34.18  ? 218 TRP C CE3 1 
ATOM   8785  C  CZ2 . TRP D 1 218 ? -9.208  34.153  -46.634 1.00 37.54  ? 218 TRP C CZ2 1 
ATOM   8786  C  CZ3 . TRP D 1 218 ? -8.037  32.267  -45.662 1.00 33.97  ? 218 TRP C CZ3 1 
ATOM   8787  C  CH2 . TRP D 1 218 ? -9.155  32.818  -46.315 1.00 34.85  ? 218 TRP C CH2 1 
ATOM   8788  N  N   . PHE D 1 219 ? -4.269  33.388  -47.321 1.00 37.78  ? 219 PHE C N   1 
ATOM   8789  C  CA  . PHE D 1 219 ? -4.646  32.066  -47.790 1.00 31.68  ? 219 PHE C CA  1 
ATOM   8790  C  C   . PHE D 1 219 ? -3.484  31.307  -48.417 1.00 31.51  ? 219 PHE C C   1 
ATOM   8791  O  O   . PHE D 1 219 ? -3.635  30.125  -48.740 1.00 32.84  ? 219 PHE C O   1 
ATOM   8792  C  CB  . PHE D 1 219 ? -5.808  32.194  -48.794 1.00 32.11  ? 219 PHE C CB  1 
ATOM   8793  C  CG  . PHE D 1 219 ? -5.513  33.120  -49.946 1.00 28.93  ? 219 PHE C CG  1 
ATOM   8794  C  CD1 . PHE D 1 219 ? -4.877  32.643  -51.086 1.00 22.53  ? 219 PHE C CD1 1 
ATOM   8795  C  CD2 . PHE D 1 219 ? -5.831  34.476  -49.874 1.00 33.96  ? 219 PHE C CD2 1 
ATOM   8796  C  CE1 . PHE D 1 219 ? -4.575  33.481  -52.140 1.00 27.67  ? 219 PHE C CE1 1 
ATOM   8797  C  CE2 . PHE D 1 219 ? -5.523  35.336  -50.930 1.00 32.57  ? 219 PHE C CE2 1 
ATOM   8798  C  CZ  . PHE D 1 219 ? -4.894  34.835  -52.066 1.00 28.77  ? 219 PHE C CZ  1 
ATOM   8799  N  N   . LEU D 1 220 ? -2.340  31.943  -48.623 1.00 30.93  ? 220 LEU C N   1 
ATOM   8800  C  CA  . LEU D 1 220 ? -1.185  31.217  -49.146 1.00 37.26  ? 220 LEU C CA  1 
ATOM   8801  C  C   . LEU D 1 220 ? -0.543  30.381  -48.044 1.00 35.65  ? 220 LEU C C   1 
ATOM   8802  O  O   . LEU D 1 220 ? -0.398  30.832  -46.904 1.00 42.52  ? 220 LEU C O   1 
ATOM   8803  C  CB  . LEU D 1 220 ? -0.167  32.190  -49.740 1.00 38.47  ? 220 LEU C CB  1 
ATOM   8804  C  CG  . LEU D 1 220 ? -0.647  33.028  -50.923 1.00 32.87  ? 220 LEU C CG  1 
ATOM   8805  C  CD1 . LEU D 1 220 ? 0.346   34.148  -51.217 1.00 43.16  ? 220 LEU C CD1 1 
ATOM   8806  C  CD2 . LEU D 1 220 ? -0.798  32.142  -52.158 1.00 32.11  ? 220 LEU C CD2 1 
ATOM   8807  N  N   . ASN D 1 221 ? -0.157  29.161  -48.386 1.00 39.07  ? 221 ASN C N   1 
ATOM   8808  C  CA  . ASN D 1 221 ? 0.461   28.244  -47.439 1.00 39.28  ? 221 ASN C CA  1 
ATOM   8809  C  C   . ASN D 1 221 ? 1.782   27.749  -48.008 1.00 46.56  ? 221 ASN C C   1 
ATOM   8810  O  O   . ASN D 1 221 ? 2.208   28.141  -49.100 1.00 51.23  ? 221 ASN C O   1 
ATOM   8811  C  CB  . ASN D 1 221 ? -0.492  27.088  -47.092 1.00 31.62  ? 221 ASN C CB  1 
ATOM   8812  C  CG  . ASN D 1 221 ? -0.922  26.299  -48.309 1.00 37.17  ? 221 ASN C CG  1 
ATOM   8813  O  OD1 . ASN D 1 221 ? -0.176  26.166  -49.286 1.00 35.60  ? 221 ASN C OD1 1 
ATOM   8814  N  ND2 . ASN D 1 221 ? -2.155  25.808  -48.279 1.00 32.96  ? 221 ASN C ND2 1 
ATOM   8815  N  N   . ARG D 1 222 ? 2.411   26.847  -47.271 1.00 52.80  ? 222 ARG C N   1 
ATOM   8816  C  CA  . ARG D 1 222 ? 3.725   26.336  -47.613 1.00 53.38  ? 222 ARG C CA  1 
ATOM   8817  C  C   . ARG D 1 222 ? 3.646   25.062  -48.437 1.00 52.96  ? 222 ARG C C   1 
ATOM   8818  O  O   . ARG D 1 222 ? 4.683   24.479  -48.764 1.00 57.84  ? 222 ARG C O   1 
ATOM   8819  C  CB  . ARG D 1 222 ? 4.483   26.066  -46.313 1.00 60.36  ? 222 ARG C CB  1 
ATOM   8820  C  CG  . ARG D 1 222 ? 3.840   24.920  -45.503 1.00 62.69  ? 222 ARG C CG  1 
ATOM   8821  C  CD  . ARG D 1 222 ? 4.495   24.707  -44.141 1.00 63.82  ? 222 ARG C CD  1 
ATOM   8822  N  NE  . ARG D 1 222 ? 4.354   25.901  -43.313 1.00 52.78  ? 222 ARG C NE  1 
ATOM   8823  C  CZ  . ARG D 1 222 ? 4.940   26.094  -42.138 1.00 56.79  ? 222 ARG C CZ  1 
ATOM   8824  N  NH1 . ARG D 1 222 ? 5.762   25.202  -41.615 1.00 55.81  ? 222 ARG C NH1 1 
ATOM   8825  N  NH2 . ARG D 1 222 ? 4.726   27.232  -41.487 1.00 63.15  ? 222 ARG C NH2 1 
ATOM   8826  N  N   . PHE D 1 223 ? 2.454   24.683  -48.872 1.00 53.81  ? 223 PHE C N   1 
ATOM   8827  C  CA  . PHE D 1 223 ? 2.241   23.403  -49.520 1.00 46.41  ? 223 PHE C CA  1 
ATOM   8828  C  C   . PHE D 1 223 ? 2.241   23.540  -51.031 1.00 42.88  ? 223 PHE C C   1 
ATOM   8829  O  O   . PHE D 1 223 ? 2.200   24.637  -51.606 1.00 40.24  ? 223 PHE C O   1 
ATOM   8830  C  CB  . PHE D 1 223 ? 0.936   22.753  -49.072 1.00 45.35  ? 223 PHE C CB  1 
ATOM   8831  C  CG  . PHE D 1 223 ? 0.866   22.478  -47.604 1.00 60.71  ? 223 PHE C CG  1 
ATOM   8832  C  CD1 . PHE D 1 223 ? 2.024   22.333  -46.857 1.00 61.32  ? 223 PHE C CD1 1 
ATOM   8833  C  CD2 . PHE D 1 223 ? -0.360  22.280  -46.985 1.00 64.61  ? 223 PHE C CD2 1 
ATOM   8834  C  CE1 . PHE D 1 223 ? 1.961   22.053  -45.508 1.00 65.92  ? 223 PHE C CE1 1 
ATOM   8835  C  CE2 . PHE D 1 223 ? -0.430  21.993  -45.637 1.00 68.40  ? 223 PHE C CE2 1 
ATOM   8836  C  CZ  . PHE D 1 223 ? 0.732   21.881  -44.897 1.00 72.13  ? 223 PHE C CZ  1 
ATOM   8837  N  N   . THR D 1 224 ? 2.352   22.381  -51.666 1.00 42.03  ? 224 THR C N   1 
ATOM   8838  C  CA  . THR D 1 224 ? 2.133   22.209  -53.085 1.00 35.97  ? 224 THR C CA  1 
ATOM   8839  C  C   . THR D 1 224 ? 1.220   21.006  -53.280 1.00 37.46  ? 224 THR C C   1 
ATOM   8840  O  O   . THR D 1 224 ? 0.890   20.282  -52.340 1.00 40.42  ? 224 THR C O   1 
ATOM   8841  C  CB  . THR D 1 224 ? 3.468   22.027  -53.828 1.00 43.32  ? 224 THR C CB  1 
ATOM   8842  O  OG1 . THR D 1 224 ? 3.301   22.309  -55.224 1.00 44.58  ? 224 THR C OG1 1 
ATOM   8843  C  CG2 . THR D 1 224 ? 3.992   20.600  -53.661 1.00 45.38  ? 224 THR C CG2 1 
ATOM   8844  N  N   . THR D 1 225 ? 0.793   20.809  -54.516 1.00 38.70  ? 225 THR C N   1 
ATOM   8845  C  CA  . THR D 1 225 ? -0.048  19.680  -54.873 1.00 40.35  ? 225 THR C CA  1 
ATOM   8846  C  C   . THR D 1 225 ? 0.262   19.306  -56.312 1.00 39.99  ? 225 THR C C   1 
ATOM   8847  O  O   . THR D 1 225 ? 1.104   19.923  -56.970 1.00 39.72  ? 225 THR C O   1 
ATOM   8848  C  CB  . THR D 1 225 ? -1.534  19.990  -54.686 1.00 42.16  ? 225 THR C CB  1 
ATOM   8849  O  OG1 . THR D 1 225 ? -2.294  18.782  -54.816 1.00 39.92  ? 225 THR C OG1 1 
ATOM   8850  C  CG2 . THR D 1 225 ? -2.006  21.029  -55.712 1.00 43.04  ? 225 THR C CG2 1 
ATOM   8851  N  N   . THR D 1 226 ? -0.412  18.274  -56.794 1.00 38.99  ? 226 THR C N   1 
ATOM   8852  C  CA  . THR D 1 226 ? -0.355  17.910  -58.196 1.00 39.90  ? 226 THR C CA  1 
ATOM   8853  C  C   . THR D 1 226 ? -1.721  18.137  -58.823 1.00 37.90  ? 226 THR C C   1 
ATOM   8854  O  O   . THR D 1 226 ? -2.733  18.271  -58.127 1.00 35.23  ? 226 THR C O   1 
ATOM   8855  C  CB  . THR D 1 226 ? 0.063   16.448  -58.377 1.00 32.68  ? 226 THR C CB  1 
ATOM   8856  O  OG1 . THR D 1 226 ? -1.000  15.597  -57.932 1.00 38.86  ? 226 THR C OG1 1 
ATOM   8857  C  CG2 . THR D 1 226 ? 1.295   16.164  -57.564 1.00 32.81  ? 226 THR C CG2 1 
ATOM   8858  N  N   . LEU D 1 227 ? -1.732  18.165  -60.158 1.00 36.11  ? 227 LEU C N   1 
ATOM   8859  C  CA  . LEU D 1 227 ? -2.992  18.256  -60.884 1.00 35.64  ? 227 LEU C CA  1 
ATOM   8860  C  C   . LEU D 1 227 ? -3.944  17.141  -60.483 1.00 36.58  ? 227 LEU C C   1 
ATOM   8861  O  O   . LEU D 1 227 ? -5.156  17.355  -60.392 1.00 41.13  ? 227 LEU C O   1 
ATOM   8862  C  CB  . LEU D 1 227 ? -2.731  18.243  -62.389 1.00 35.23  ? 227 LEU C CB  1 
ATOM   8863  C  CG  . LEU D 1 227 ? -3.567  19.198  -63.245 1.00 33.57  ? 227 LEU C CG  1 
ATOM   8864  C  CD1 . LEU D 1 227 ? -3.702  20.565  -62.607 1.00 31.75  ? 227 LEU C CD1 1 
ATOM   8865  C  CD2 . LEU D 1 227 ? -2.957  19.286  -64.624 1.00 31.47  ? 227 LEU C CD2 1 
ATOM   8866  N  N   . ASN D 1 228 ? -3.421  15.942  -60.245 1.00 39.80  ? 228 ASN C N   1 
ATOM   8867  C  CA  . ASN D 1 228 ? -4.296  14.830  -59.889 1.00 42.89  ? 228 ASN C CA  1 
ATOM   8868  C  C   . ASN D 1 228 ? -4.938  15.037  -58.519 1.00 40.73  ? 228 ASN C C   1 
ATOM   8869  O  O   . ASN D 1 228 ? -6.161  14.916  -58.378 1.00 45.08  ? 228 ASN C O   1 
ATOM   8870  C  CB  . ASN D 1 228 ? -3.516  13.511  -59.935 1.00 53.49  ? 228 ASN C CB  1 
ATOM   8871  C  CG  . ASN D 1 228 ? -3.257  13.025  -61.364 1.00 59.10  ? 228 ASN C CG  1 
ATOM   8872  O  OD1 . ASN D 1 228 ? -3.623  13.690  -62.344 1.00 53.38  ? 228 ASN C OD1 1 
ATOM   8873  N  ND2 . ASN D 1 228 ? -2.615  11.860  -61.483 1.00 46.80  ? 228 ASN C ND2 1 
ATOM   8874  N  N   . ASP D 1 229 ? -4.133  15.336  -57.488 1.00 43.60  ? 229 ASP C N   1 
ATOM   8875  C  CA  . ASP D 1 229 ? -4.700  15.502  -56.145 1.00 40.21  ? 229 ASP C CA  1 
ATOM   8876  C  C   . ASP D 1 229 ? -5.582  16.730  -56.031 1.00 34.51  ? 229 ASP C C   1 
ATOM   8877  O  O   . ASP D 1 229 ? -6.558  16.711  -55.274 1.00 33.55  ? 229 ASP C O   1 
ATOM   8878  C  CB  . ASP D 1 229 ? -3.616  15.553  -55.070 1.00 42.51  ? 229 ASP C CB  1 
ATOM   8879  C  CG  . ASP D 1 229 ? -3.373  14.193  -54.417 1.00 58.82  ? 229 ASP C CG  1 
ATOM   8880  O  OD1 . ASP D 1 229 ? -3.766  13.152  -55.010 1.00 53.42  ? 229 ASP C OD1 1 
ATOM   8881  O  OD2 . ASP D 1 229 ? -2.830  14.175  -53.281 1.00 59.69  ? 229 ASP C OD2 1 
ATOM   8882  N  N   . PHE D 1 230 ? -5.258  17.810  -56.741 1.00 38.23  ? 230 PHE C N   1 
ATOM   8883  C  CA  . PHE D 1 230 ? -6.138  18.974  -56.704 1.00 36.80  ? 230 PHE C CA  1 
ATOM   8884  C  C   . PHE D 1 230 ? -7.504  18.635  -57.274 1.00 37.69  ? 230 PHE C C   1 
ATOM   8885  O  O   . PHE D 1 230 ? -8.539  19.006  -56.704 1.00 35.24  ? 230 PHE C O   1 
ATOM   8886  C  CB  . PHE D 1 230 ? -5.548  20.148  -57.472 1.00 39.59  ? 230 PHE C CB  1 
ATOM   8887  C  CG  . PHE D 1 230 ? -6.476  21.327  -57.528 1.00 39.89  ? 230 PHE C CG  1 
ATOM   8888  C  CD1 . PHE D 1 230 ? -6.564  22.201  -56.454 1.00 36.45  ? 230 PHE C CD1 1 
ATOM   8889  C  CD2 . PHE D 1 230 ? -7.298  21.527  -58.621 1.00 36.40  ? 230 PHE C CD2 1 
ATOM   8890  C  CE1 . PHE D 1 230 ? -7.435  23.273  -56.481 1.00 34.72  ? 230 PHE C CE1 1 
ATOM   8891  C  CE2 . PHE D 1 230 ? -8.170  22.594  -58.652 1.00 37.14  ? 230 PHE C CE2 1 
ATOM   8892  C  CZ  . PHE D 1 230 ? -8.236  23.470  -57.580 1.00 34.62  ? 230 PHE C CZ  1 
ATOM   8893  N  N   . ASN D 1 231 ? -7.526  17.948  -58.421 1.00 36.36  ? 231 ASN C N   1 
ATOM   8894  C  CA  . ASN D 1 231 ? -8.805  17.575  -59.007 1.00 37.08  ? 231 ASN C CA  1 
ATOM   8895  C  C   . ASN D 1 231 ? -9.529  16.566  -58.135 1.00 35.30  ? 231 ASN C C   1 
ATOM   8896  O  O   . ASN D 1 231 ? -10.756 16.552  -58.115 1.00 36.74  ? 231 ASN C O   1 
ATOM   8897  C  CB  . ASN D 1 231 ? -8.611  17.046  -60.425 1.00 33.91  ? 231 ASN C CB  1 
ATOM   8898  C  CG  . ASN D 1 231 ? -8.455  18.167  -61.439 1.00 39.41  ? 231 ASN C CG  1 
ATOM   8899  O  OD1 . ASN D 1 231 ? -9.079  19.229  -61.314 1.00 36.06  ? 231 ASN C OD1 1 
ATOM   8900  N  ND2 . ASN D 1 231 ? -7.619  17.943  -62.447 1.00 35.66  ? 231 ASN C ND2 1 
ATOM   8901  N  N   . LEU D 1 232 ? -8.789  15.772  -57.358 1.00 35.98  ? 232 LEU C N   1 
ATOM   8902  C  CA  . LEU D 1 232 ? -9.409  14.899  -56.363 1.00 40.84  ? 232 LEU C CA  1 
ATOM   8903  C  C   . LEU D 1 232 ? -10.339 15.671  -55.444 1.00 43.34  ? 232 LEU C C   1 
ATOM   8904  O  O   . LEU D 1 232 ? -11.449 15.217  -55.143 1.00 40.84  ? 232 LEU C O   1 
ATOM   8905  C  CB  . LEU D 1 232 ? -8.330  14.229  -55.515 1.00 41.22  ? 232 LEU C CB  1 
ATOM   8906  C  CG  . LEU D 1 232 ? -7.923  12.824  -55.885 1.00 48.81  ? 232 LEU C CG  1 
ATOM   8907  C  CD1 . LEU D 1 232 ? -7.175  12.155  -54.744 1.00 49.26  ? 232 LEU C CD1 1 
ATOM   8908  C  CD2 . LEU D 1 232 ? -9.203  12.110  -56.157 1.00 55.40  ? 232 LEU C CD2 1 
ATOM   8909  N  N   . VAL D 1 233 ? -9.894  16.831  -54.970 1.00 40.71  ? 233 VAL C N   1 
ATOM   8910  C  CA  . VAL D 1 233 ? -10.707 17.611  -54.050 1.00 35.78  ? 233 VAL C CA  1 
ATOM   8911  C  C   . VAL D 1 233 ? -11.779 18.384  -54.800 1.00 37.08  ? 233 VAL C C   1 
ATOM   8912  O  O   . VAL D 1 233 ? -12.951 18.382  -54.410 1.00 39.39  ? 233 VAL C O   1 
ATOM   8913  C  CB  . VAL D 1 233 ? -9.809  18.547  -53.223 1.00 42.17  ? 233 VAL C CB  1 
ATOM   8914  C  CG1 . VAL D 1 233 ? -10.618 19.238  -52.141 1.00 39.04  ? 233 VAL C CG1 1 
ATOM   8915  C  CG2 . VAL D 1 233 ? -8.644  17.767  -52.631 1.00 42.76  ? 233 VAL C CG2 1 
ATOM   8916  N  N   . ALA D 1 234 ? -11.390 19.036  -55.902 1.00 35.76  ? 234 ALA C N   1 
ATOM   8917  C  CA  . ALA D 1 234 ? -12.290 19.954  -56.593 1.00 37.63  ? 234 ALA C CA  1 
ATOM   8918  C  C   . ALA D 1 234 ? -13.573 19.276  -57.068 1.00 35.40  ? 234 ALA C C   1 
ATOM   8919  O  O   . ALA D 1 234 ? -14.662 19.837  -56.912 1.00 32.63  ? 234 ALA C O   1 
ATOM   8920  C  CB  . ALA D 1 234 ? -11.551 20.617  -57.762 1.00 37.39  ? 234 ALA C CB  1 
ATOM   8921  N  N   . MET D 1 235 ? -13.480 18.060  -57.617 1.00 38.57  ? 235 MET C N   1 
ATOM   8922  C  CA  . MET D 1 235 ? -14.689 17.387  -58.100 1.00 42.53  ? 235 MET C CA  1 
ATOM   8923  C  C   . MET D 1 235 ? -15.677 17.146  -56.973 1.00 38.54  ? 235 MET C C   1 
ATOM   8924  O  O   . MET D 1 235 ? -16.896 17.224  -57.179 1.00 38.74  ? 235 MET C O   1 
ATOM   8925  C  CB  . MET D 1 235 ? -14.349 16.063  -58.765 1.00 36.66  ? 235 MET C CB  1 
ATOM   8926  C  CG  . MET D 1 235 ? -13.157 16.154  -59.612 1.00 43.03  ? 235 MET C CG  1 
ATOM   8927  S  SD  . MET D 1 235 ? -13.295 17.205  -61.049 1.00 68.22  ? 235 MET C SD  1 
ATOM   8928  C  CE  . MET D 1 235 ? -11.952 18.316  -60.659 1.00 44.75  ? 235 MET C CE  1 
ATOM   8929  N  N   . LYS D 1 236 ? -15.171 16.824  -55.780 1.00 34.53  ? 236 LYS C N   1 
ATOM   8930  C  CA  . LYS D 1 236 ? -16.055 16.660  -54.634 1.00 36.62  ? 236 LYS C CA  1 
ATOM   8931  C  C   . LYS D 1 236 ? -16.867 17.925  -54.398 1.00 37.46  ? 236 LYS C C   1 
ATOM   8932  O  O   . LYS D 1 236 ? -18.009 17.852  -53.937 1.00 36.87  ? 236 LYS C O   1 
ATOM   8933  C  CB  . LYS D 1 236 ? -15.240 16.294  -53.394 1.00 37.65  ? 236 LYS C CB  1 
ATOM   8934  C  CG  . LYS D 1 236 ? -14.582 14.928  -53.476 1.00 48.59  ? 236 LYS C CG  1 
ATOM   8935  C  CD  . LYS D 1 236 ? -13.485 14.777  -52.420 1.00 51.17  ? 236 LYS C CD  1 
ATOM   8936  C  CE  . LYS D 1 236 ? -12.619 13.549  -52.677 1.00 53.17  ? 236 LYS C CE  1 
ATOM   8937  N  NZ  . LYS D 1 236 ? -11.293 13.653  -51.986 1.00 58.90  ? 236 LYS C NZ  1 
ATOM   8938  N  N   . TYR D 1 237 ? -16.301 19.089  -54.726 1.00 38.77  ? 237 TYR C N   1 
ATOM   8939  C  CA  . TYR D 1 237 ? -16.945 20.379  -54.519 1.00 32.80  ? 237 TYR C CA  1 
ATOM   8940  C  C   . TYR D 1 237 ? -17.581 20.944  -55.789 1.00 31.19  ? 237 TYR C C   1 
ATOM   8941  O  O   . TYR D 1 237 ? -17.905 22.138  -55.822 1.00 31.12  ? 237 TYR C O   1 
ATOM   8942  C  CB  . TYR D 1 237 ? -15.936 21.367  -53.938 1.00 30.59  ? 237 TYR C CB  1 
ATOM   8943  C  CG  . TYR D 1 237 ? -15.541 21.010  -52.531 1.00 35.29  ? 237 TYR C CG  1 
ATOM   8944  C  CD1 . TYR D 1 237 ? -14.545 20.060  -52.277 1.00 37.45  ? 237 TYR C CD1 1 
ATOM   8945  C  CD2 . TYR D 1 237 ? -16.162 21.612  -51.449 1.00 36.36  ? 237 TYR C CD2 1 
ATOM   8946  C  CE1 . TYR D 1 237 ? -14.187 19.723  -50.975 1.00 34.86  ? 237 TYR C CE1 1 
ATOM   8947  C  CE2 . TYR D 1 237 ? -15.814 21.279  -50.145 1.00 40.76  ? 237 TYR C CE2 1 
ATOM   8948  C  CZ  . TYR D 1 237 ? -14.830 20.337  -49.914 1.00 33.88  ? 237 TYR C CZ  1 
ATOM   8949  O  OH  . TYR D 1 237 ? -14.498 20.026  -48.615 1.00 39.68  ? 237 TYR C OH  1 
ATOM   8950  N  N   . ASN D 1 238 ? -17.774 20.121  -56.825 1.00 24.53  ? 238 ASN C N   1 
ATOM   8951  C  CA  . ASN D 1 238 ? -18.474 20.547  -58.043 1.00 26.90  ? 238 ASN C CA  1 
ATOM   8952  C  C   . ASN D 1 238 ? -17.729 21.679  -58.770 1.00 32.76  ? 238 ASN C C   1 
ATOM   8953  O  O   . ASN D 1 238 ? -18.329 22.611  -59.317 1.00 30.82  ? 238 ASN C O   1 
ATOM   8954  C  CB  . ASN D 1 238 ? -19.913 20.955  -57.713 1.00 34.02  ? 238 ASN C CB  1 
ATOM   8955  C  CG  . ASN D 1 238 ? -20.834 20.900  -58.914 1.00 48.54  ? 238 ASN C CG  1 
ATOM   8956  O  OD1 . ASN D 1 238 ? -20.602 20.136  -59.864 1.00 57.11  ? 238 ASN C OD1 1 
ATOM   8957  N  ND2 . ASN D 1 238 ? -21.896 21.705  -58.880 1.00 37.85  ? 238 ASN C ND2 1 
ATOM   8958  N  N   . TYR D 1 239 ? -16.408 21.594  -58.776 1.00 28.00  ? 239 TYR C N   1 
ATOM   8959  C  CA  . TYR D 1 239 ? -15.556 22.461  -59.571 1.00 26.93  ? 239 TYR C CA  1 
ATOM   8960  C  C   . TYR D 1 239 ? -15.215 21.784  -60.903 1.00 31.18  ? 239 TYR C C   1 
ATOM   8961  O  O   . TYR D 1 239 ? -15.204 20.555  -61.013 1.00 28.42  ? 239 TYR C O   1 
ATOM   8962  C  CB  . TYR D 1 239 ? -14.288 22.771  -58.775 1.00 30.56  ? 239 TYR C CB  1 
ATOM   8963  C  CG  . TYR D 1 239 ? -14.358 23.983  -57.867 1.00 26.19  ? 239 TYR C CG  1 
ATOM   8964  C  CD1 . TYR D 1 239 ? -15.380 24.134  -56.944 1.00 23.67  ? 239 TYR C CD1 1 
ATOM   8965  C  CD2 . TYR D 1 239 ? -13.351 24.936  -57.883 1.00 22.88  ? 239 TYR C CD2 1 
ATOM   8966  C  CE1 . TYR D 1 239 ? -15.436 25.239  -56.105 1.00 22.79  ? 239 TYR C CE1 1 
ATOM   8967  C  CE2 . TYR D 1 239 ? -13.390 26.036  -57.037 1.00 22.42  ? 239 TYR C CE2 1 
ATOM   8968  C  CZ  . TYR D 1 239 ? -14.431 26.187  -56.158 1.00 25.11  ? 239 TYR C CZ  1 
ATOM   8969  O  OH  . TYR D 1 239 ? -14.455 27.282  -55.327 1.00 24.14  ? 239 TYR C OH  1 
ATOM   8970  N  N   . GLU D 1 240 ? -14.983 22.585  -61.927 1.00 31.06  ? 240 GLU C N   1 
ATOM   8971  C  CA  . GLU D 1 240 ? -14.602 22.048  -63.248 1.00 28.96  ? 240 GLU C CA  1 
ATOM   8972  C  C   . GLU D 1 240 ? -13.212 21.432  -63.132 1.00 32.53  ? 240 GLU C C   1 
ATOM   8973  O  O   . GLU D 1 240 ? -12.372 21.980  -62.430 1.00 32.62  ? 240 GLU C O   1 
ATOM   8974  C  CB  . GLU D 1 240 ? -14.630 23.143  -64.307 1.00 27.58  ? 240 GLU C CB  1 
ATOM   8975  C  CG  . GLU D 1 240 ? -16.007 23.413  -64.862 1.00 35.50  ? 240 GLU C CG  1 
ATOM   8976  C  CD  . GLU D 1 240 ? -16.460 22.400  -65.892 1.00 41.24  ? 240 GLU C CD  1 
ATOM   8977  O  OE1 . GLU D 1 240 ? -15.606 21.918  -66.658 1.00 41.37  ? 240 GLU C OE1 1 
ATOM   8978  O  OE2 . GLU D 1 240 ? -17.663 22.100  -65.924 1.00 40.51  ? 240 GLU C OE2 1 
ATOM   8979  N  N   . PRO D 1 241 ? -12.958 20.293  -63.789 1.00 31.06  ? 241 PRO C N   1 
ATOM   8980  C  CA  . PRO D 1 241 ? -11.628 19.677  -63.764 1.00 36.06  ? 241 PRO C CA  1 
ATOM   8981  C  C   . PRO D 1 241 ? -10.579 20.661  -64.249 1.00 32.46  ? 241 PRO C C   1 
ATOM   8982  O  O   . PRO D 1 241 ? -10.764 21.346  -65.255 1.00 32.75  ? 241 PRO C O   1 
ATOM   8983  C  CB  . PRO D 1 241 ? -11.766 18.477  -64.712 1.00 33.67  ? 241 PRO C CB  1 
ATOM   8984  C  CG  . PRO D 1 241 ? -13.226 18.190  -64.758 1.00 38.13  ? 241 PRO C CG  1 
ATOM   8985  C  CD  . PRO D 1 241 ? -13.910 19.537  -64.612 1.00 33.29  ? 241 PRO C CD  1 
ATOM   8986  N  N   . LEU D 1 242 ? -9.467  20.727  -63.530 1.00 33.37  ? 242 LEU C N   1 
ATOM   8987  C  CA  . LEU D 1 242 ? -8.382  21.600  -63.940 1.00 33.23  ? 242 LEU C CA  1 
ATOM   8988  C  C   . LEU D 1 242 ? -7.527  20.840  -64.941 1.00 32.74  ? 242 LEU C C   1 
ATOM   8989  O  O   . LEU D 1 242 ? -7.169  19.686  -64.709 1.00 32.34  ? 242 LEU C O   1 
ATOM   8990  C  CB  . LEU D 1 242 ? -7.544  22.072  -62.750 1.00 27.52  ? 242 LEU C CB  1 
ATOM   8991  C  CG  . LEU D 1 242 ? -6.690  23.300  -63.066 1.00 29.54  ? 242 LEU C CG  1 
ATOM   8992  C  CD1 . LEU D 1 242 ? -7.590  24.521  -63.174 1.00 31.64  ? 242 LEU C CD1 1 
ATOM   8993  C  CD2 . LEU D 1 242 ? -5.690  23.519  -61.980 1.00 31.06  ? 242 LEU C CD2 1 
ATOM   8994  N  N   . THR D 1 243 ? -7.263  21.465  -66.077 1.00 33.43  ? 243 THR C N   1 
ATOM   8995  C  CA  . THR D 1 243 ? -6.505  20.839  -67.144 1.00 30.23  ? 243 THR C CA  1 
ATOM   8996  C  C   . THR D 1 243 ? -5.124  21.471  -67.204 1.00 31.03  ? 243 THR C C   1 
ATOM   8997  O  O   . THR D 1 243 ? -4.854  22.487  -66.562 1.00 30.43  ? 243 THR C O   1 
ATOM   8998  C  CB  . THR D 1 243 ? -7.260  20.951  -68.489 1.00 31.33  ? 243 THR C CB  1 
ATOM   8999  O  OG1 . THR D 1 243 ? -7.357  22.325  -68.906 1.00 28.20  ? 243 THR C OG1 1 
ATOM   9000  C  CG2 . THR D 1 243 ? -8.670  20.348  -68.383 1.00 31.73  ? 243 THR C CG2 1 
ATOM   9001  N  N   . GLN D 1 244 ? -4.227  20.822  -67.947 1.00 30.75  ? 244 GLN C N   1 
ATOM   9002  C  CA  . GLN D 1 244 ? -2.914  21.408  -68.176 1.00 31.80  ? 244 GLN C CA  1 
ATOM   9003  C  C   . GLN D 1 244 ? -3.031  22.685  -69.004 1.00 30.99  ? 244 GLN C C   1 
ATOM   9004  O  O   . GLN D 1 244 ? -2.269  23.634  -68.800 1.00 29.26  ? 244 GLN C O   1 
ATOM   9005  C  CB  . GLN D 1 244 ? -2.004  20.386  -68.857 1.00 35.32  ? 244 GLN C CB  1 
ATOM   9006  C  CG  . GLN D 1 244 ? -0.560  20.816  -68.996 1.00 36.21  ? 244 GLN C CG  1 
ATOM   9007  C  CD  . GLN D 1 244 ? 0.074   21.097  -67.641 1.00 40.11  ? 244 GLN C CD  1 
ATOM   9008  O  OE1 . GLN D 1 244 ? -0.238  20.431  -66.643 1.00 34.31  ? 244 GLN C OE1 1 
ATOM   9009  N  NE2 . GLN D 1 244 ? 0.985   22.074  -67.601 1.00 30.74  ? 244 GLN C NE2 1 
ATOM   9010  N  N   . ASP D 1 245 ? -4.001  22.730  -69.915 1.00 31.57  ? 245 ASP C N   1 
ATOM   9011  C  CA  . ASP D 1 245 ? -4.306  23.961  -70.622 1.00 27.50  ? 245 ASP C CA  1 
ATOM   9012  C  C   . ASP D 1 245 ? -4.614  25.082  -69.638 1.00 31.19  ? 245 ASP C C   1 
ATOM   9013  O  O   . ASP D 1 245 ? -4.214  26.236  -69.840 1.00 31.49  ? 245 ASP C O   1 
ATOM   9014  C  CB  . ASP D 1 245 ? -5.506  23.735  -71.534 1.00 35.09  ? 245 ASP C CB  1 
ATOM   9015  C  CG  . ASP D 1 245 ? -5.132  23.133  -72.878 1.00 38.06  ? 245 ASP C CG  1 
ATOM   9016  O  OD1 . ASP D 1 245 ? -4.044  22.541  -73.015 1.00 35.45  ? 245 ASP C OD1 1 
ATOM   9017  O  OD2 . ASP D 1 245 ? -5.955  23.256  -73.811 1.00 45.12  ? 245 ASP C OD2 1 
ATOM   9018  N  N   . HIS D 1 246 ? -5.335  24.757  -68.569 1.00 25.03  ? 246 HIS C N   1 
ATOM   9019  C  CA  . HIS D 1 246 ? -5.657  25.747  -67.552 1.00 28.23  ? 246 HIS C CA  1 
ATOM   9020  C  C   . HIS D 1 246 ? -4.412  26.191  -66.786 1.00 26.88  ? 246 HIS C C   1 
ATOM   9021  O  O   . HIS D 1 246 ? -4.233  27.387  -66.521 1.00 23.32  ? 246 HIS C O   1 
ATOM   9022  C  CB  . HIS D 1 246 ? -6.717  25.176  -66.611 1.00 29.87  ? 246 HIS C CB  1 
ATOM   9023  C  CG  . HIS D 1 246 ? -8.087  25.091  -67.207 1.00 26.91  ? 246 HIS C CG  1 
ATOM   9024  N  ND1 . HIS D 1 246 ? -8.980  24.099  -66.866 1.00 27.18  ? 246 HIS C ND1 1 
ATOM   9025  C  CD2 . HIS D 1 246 ? -8.740  25.900  -68.077 1.00 31.56  ? 246 HIS C CD2 1 
ATOM   9026  C  CE1 . HIS D 1 246 ? -10.122 24.293  -67.507 1.00 29.03  ? 246 HIS C CE1 1 
ATOM   9027  N  NE2 . HIS D 1 246 ? -10.003 25.377  -68.253 1.00 26.73  ? 246 HIS C NE2 1 
ATOM   9028  N  N   . VAL D 1 247 ? -3.558  25.236  -66.403 1.00 24.16  ? 247 VAL C N   1 
ATOM   9029  C  CA  . VAL D 1 247 ? -2.297  25.567  -65.746 1.00 28.59  ? 247 VAL C CA  1 
ATOM   9030  C  C   . VAL D 1 247 ? -1.472  26.497  -66.628 1.00 31.28  ? 247 VAL C C   1 
ATOM   9031  O  O   . VAL D 1 247 ? -0.918  27.501  -66.160 1.00 28.37  ? 247 VAL C O   1 
ATOM   9032  C  CB  . VAL D 1 247 ? -1.530  24.277  -65.394 1.00 30.38  ? 247 VAL C CB  1 
ATOM   9033  C  CG1 . VAL D 1 247 ? -0.206  24.585  -64.715 1.00 23.98  ? 247 VAL C CG1 1 
ATOM   9034  C  CG2 . VAL D 1 247 ? -2.398  23.359  -64.531 1.00 31.84  ? 247 VAL C CG2 1 
ATOM   9035  N  N   . ASP D 1 248 ? -1.387  26.183  -67.922 1.00 31.29  ? 248 ASP C N   1 
ATOM   9036  C  CA  . ASP D 1 248 ? -0.609  27.007  -68.839 1.00 30.98  ? 248 ASP C CA  1 
ATOM   9037  C  C   . ASP D 1 248 ? -1.194  28.412  -68.964 1.00 30.30  ? 248 ASP C C   1 
ATOM   9038  O  O   . ASP D 1 248 ? -0.454  29.402  -68.917 1.00 29.34  ? 248 ASP C O   1 
ATOM   9039  C  CB  . ASP D 1 248 ? -0.535  26.324  -70.201 1.00 33.65  ? 248 ASP C CB  1 
ATOM   9040  C  CG  . ASP D 1 248 ? 0.141   24.962  -70.141 1.00 35.01  ? 248 ASP C CG  1 
ATOM   9041  O  OD1 . ASP D 1 248 ? 0.997   24.755  -69.244 1.00 37.22  ? 248 ASP C OD1 1 
ATOM   9042  O  OD2 . ASP D 1 248 ? -0.169  24.113  -71.014 1.00 34.84  ? 248 ASP C OD2 1 
ATOM   9043  N  N   . ILE D 1 249 ? -2.524  28.512  -69.063 1.00 31.07  ? 249 ILE C N   1 
ATOM   9044  C  CA  . ILE D 1 249 ? -3.206  29.802  -69.196 1.00 36.89  ? 249 ILE C CA  1 
ATOM   9045  C  C   . ILE D 1 249 ? -2.953  30.690  -67.972 1.00 30.35  ? 249 ILE C C   1 
ATOM   9046  O  O   . ILE D 1 249 ? -2.823  31.913  -68.096 1.00 33.48  ? 249 ILE C O   1 
ATOM   9047  C  CB  . ILE D 1 249 ? -4.714  29.587  -69.476 1.00 34.47  ? 249 ILE C CB  1 
ATOM   9048  C  CG1 . ILE D 1 249 ? -4.921  29.146  -70.934 1.00 33.63  ? 249 ILE C CG1 1 
ATOM   9049  C  CG2 . ILE D 1 249 ? -5.522  30.861  -69.236 1.00 32.73  ? 249 ILE C CG2 1 
ATOM   9050  C  CD1 . ILE D 1 249 ? -6.278  28.571  -71.223 1.00 35.98  ? 249 ILE C CD1 1 
ATOM   9051  N  N   . LEU D 1 250 ? -2.857  30.093  -66.781 1.00 28.87  ? 250 LEU C N   1 
ATOM   9052  C  CA  . LEU D 1 250 ? -2.504  30.831  -65.567 1.00 31.42  ? 250 LEU C CA  1 
ATOM   9053  C  C   . LEU D 1 250 ? -1.025  31.232  -65.494 1.00 27.11  ? 250 LEU C C   1 
ATOM   9054  O  O   . LEU D 1 250 ? -0.633  31.876  -64.514 1.00 28.06  ? 250 LEU C O   1 
ATOM   9055  C  CB  . LEU D 1 250 ? -2.886  30.013  -64.327 1.00 22.24  ? 250 LEU C CB  1 
ATOM   9056  C  CG  . LEU D 1 250 ? -4.393  30.028  -64.062 1.00 23.93  ? 250 LEU C CG  1 
ATOM   9057  C  CD1 . LEU D 1 250 ? -4.815  28.964  -63.079 1.00 23.53  ? 250 LEU C CD1 1 
ATOM   9058  C  CD2 . LEU D 1 250 ? -4.787  31.400  -63.534 1.00 21.81  ? 250 LEU C CD2 1 
ATOM   9059  N  N   . GLY D 1 251 ? -0.206  30.867  -66.480 1.00 28.51  ? 251 GLY C N   1 
ATOM   9060  C  CA  . GLY D 1 251 ? 1.211   31.172  -66.504 1.00 31.22  ? 251 GLY C CA  1 
ATOM   9061  C  C   . GLY D 1 251 ? 1.622   32.617  -66.256 1.00 29.27  ? 251 GLY C C   1 
ATOM   9062  O  O   . GLY D 1 251 ? 2.400   32.902  -65.344 1.00 28.93  ? 251 GLY C O   1 
ATOM   9063  N  N   . PRO D 1 252 ? 1.129   33.553  -67.073 1.00 30.98  ? 252 PRO C N   1 
ATOM   9064  C  CA  . PRO D 1 252 ? 1.507   34.968  -66.865 1.00 29.55  ? 252 PRO C CA  1 
ATOM   9065  C  C   . PRO D 1 252 ? 1.198   35.478  -65.470 1.00 28.49  ? 252 PRO C C   1 
ATOM   9066  O  O   . PRO D 1 252 ? 2.036   36.165  -64.872 1.00 27.62  ? 252 PRO C O   1 
ATOM   9067  C  CB  . PRO D 1 252 ? 0.697   35.711  -67.936 1.00 22.21  ? 252 PRO C CB  1 
ATOM   9068  C  CG  . PRO D 1 252 ? 0.514   34.676  -69.026 1.00 30.45  ? 252 PRO C CG  1 
ATOM   9069  C  CD  . PRO D 1 252 ? 0.369   33.355  -68.319 1.00 27.59  ? 252 PRO C CD  1 
ATOM   9070  N  N   . LEU D 1 253 ? 0.032   35.142  -64.915 1.00 26.06  ? 253 LEU C N   1 
ATOM   9071  C  CA  . LEU D 1 253 ? -0.250  35.576  -63.551 1.00 27.53  ? 253 LEU C CA  1 
ATOM   9072  C  C   . LEU D 1 253 ? 0.685   34.894  -62.563 1.00 28.30  ? 253 LEU C C   1 
ATOM   9073  O  O   . LEU D 1 253 ? 1.094   35.504  -61.563 1.00 33.92  ? 253 LEU C O   1 
ATOM   9074  C  CB  . LEU D 1 253 ? -1.711  35.296  -63.194 1.00 29.75  ? 253 LEU C CB  1 
ATOM   9075  C  CG  . LEU D 1 253 ? -2.765  36.183  -63.859 1.00 30.19  ? 253 LEU C CG  1 
ATOM   9076  C  CD1 . LEU D 1 253 ? -4.185  35.693  -63.565 1.00 23.37  ? 253 LEU C CD1 1 
ATOM   9077  C  CD2 . LEU D 1 253 ? -2.587  37.634  -63.411 1.00 29.26  ? 253 LEU C CD2 1 
ATOM   9078  N  N   . SER D 1 254 ? 1.063   33.650  -62.848 1.00 27.03  ? 254 SER C N   1 
ATOM   9079  C  CA  . SER D 1 254 ? 2.022   32.945  -62.007 1.00 28.83  ? 254 SER C CA  1 
ATOM   9080  C  C   . SER D 1 254 ? 3.387   33.623  -62.055 1.00 30.00  ? 254 SER C C   1 
ATOM   9081  O  O   . SER D 1 254 ? 4.055   33.772  -61.027 1.00 28.73  ? 254 SER C O   1 
ATOM   9082  C  CB  . SER D 1 254 ? 2.107   31.490  -62.462 1.00 32.10  ? 254 SER C CB  1 
ATOM   9083  O  OG  . SER D 1 254 ? 3.081   30.763  -61.740 1.00 34.84  ? 254 SER C OG  1 
ATOM   9084  N  N   . ALA D 1 255 ? 3.800   34.065  -63.243 1.00 33.69  ? 255 ALA C N   1 
ATOM   9085  C  CA  . ALA D 1 255 ? 5.088   34.737  -63.395 1.00 38.48  ? 255 ALA C CA  1 
ATOM   9086  C  C   . ALA D 1 255 ? 5.076   36.108  -62.724 1.00 34.68  ? 255 ALA C C   1 
ATOM   9087  O  O   . ALA D 1 255 ? 6.091   36.550  -62.178 1.00 35.82  ? 255 ALA C O   1 
ATOM   9088  C  CB  . ALA D 1 255 ? 5.444   34.858  -64.880 1.00 30.66  ? 255 ALA C CB  1 
ATOM   9089  N  N   . GLN D 1 256 ? 3.944   36.805  -62.784 1.00 34.42  ? 256 GLN C N   1 
ATOM   9090  C  CA  . GLN D 1 256 ? 3.854   38.117  -62.163 1.00 33.40  ? 256 GLN C CA  1 
ATOM   9091  C  C   . GLN D 1 256 ? 4.001   38.051  -60.648 1.00 30.51  ? 256 GLN C C   1 
ATOM   9092  O  O   . GLN D 1 256 ? 4.539   38.981  -60.045 1.00 38.79  ? 256 GLN C O   1 
ATOM   9093  C  CB  . GLN D 1 256 ? 2.542   38.786  -62.571 1.00 35.15  ? 256 GLN C CB  1 
ATOM   9094  C  CG  . GLN D 1 256 ? 2.173   39.999  -61.750 1.00 38.08  ? 256 GLN C CG  1 
ATOM   9095  C  CD  . GLN D 1 256 ? 1.102   40.860  -62.417 1.00 49.67  ? 256 GLN C CD  1 
ATOM   9096  O  OE1 . GLN D 1 256 ? 0.639   40.562  -63.530 1.00 42.73  ? 256 GLN C OE1 1 
ATOM   9097  N  NE2 . GLN D 1 256 ? 0.727   41.955  -61.750 1.00 47.84  ? 256 GLN C NE2 1 
ATOM   9098  N  N   . THR D 1 257 ? 3.533   36.977  -60.012 1.00 38.15  ? 257 THR C N   1 
ATOM   9099  C  CA  . THR D 1 257 ? 3.604   36.849  -58.557 1.00 33.79  ? 257 THR C CA  1 
ATOM   9100  C  C   . THR D 1 257 ? 4.759   35.994  -58.045 1.00 35.12  ? 257 THR C C   1 
ATOM   9101  O  O   . THR D 1 257 ? 5.095   36.084  -56.862 1.00 36.19  ? 257 THR C O   1 
ATOM   9102  C  CB  . THR D 1 257 ? 2.291   36.274  -58.000 1.00 35.74  ? 257 THR C CB  1 
ATOM   9103  O  OG1 . THR D 1 257 ? 1.993   35.022  -58.639 1.00 32.49  ? 257 THR C OG1 1 
ATOM   9104  C  CG2 . THR D 1 257 ? 1.152   37.249  -58.213 1.00 35.93  ? 257 THR C CG2 1 
ATOM   9105  N  N   . GLY D 1 258 ? 5.349   35.142  -58.871 1.00 36.41  ? 258 GLY C N   1 
ATOM   9106  C  CA  . GLY D 1 258 ? 6.321   34.224  -58.323 1.00 30.01  ? 258 GLY C CA  1 
ATOM   9107  C  C   . GLY D 1 258 ? 5.701   33.134  -57.486 1.00 34.50  ? 258 GLY C C   1 
ATOM   9108  O  O   . GLY D 1 258 ? 6.391   32.518  -56.675 1.00 40.71  ? 258 GLY C O   1 
ATOM   9109  N  N   . ILE D 1 259 ? 4.411   32.862  -57.678 1.00 39.11  ? 259 ILE C N   1 
ATOM   9110  C  CA  . ILE D 1 259 ? 3.694   31.782  -56.999 1.00 36.29  ? 259 ILE C CA  1 
ATOM   9111  C  C   . ILE D 1 259 ? 3.335   30.725  -58.039 1.00 33.80  ? 259 ILE C C   1 
ATOM   9112  O  O   . ILE D 1 259 ? 2.585   31.003  -58.985 1.00 37.45  ? 259 ILE C O   1 
ATOM   9113  C  CB  . ILE D 1 259 ? 2.437   32.308  -56.290 1.00 30.95  ? 259 ILE C CB  1 
ATOM   9114  C  CG1 . ILE D 1 259 ? 2.819   33.365  -55.266 1.00 29.85  ? 259 ILE C CG1 1 
ATOM   9115  C  CG2 . ILE D 1 259 ? 1.656   31.177  -55.641 1.00 27.65  ? 259 ILE C CG2 1 
ATOM   9116  C  CD1 . ILE D 1 259 ? 1.638   34.145  -54.776 1.00 30.40  ? 259 ILE C CD1 1 
ATOM   9117  N  N   . ALA D 1 260 ? 3.874   29.522  -57.882 1.00 26.75  ? 260 ALA C N   1 
ATOM   9118  C  CA  . ALA D 1 260 ? 3.594   28.482  -58.855 1.00 25.25  ? 260 ALA C CA  1 
ATOM   9119  C  C   . ALA D 1 260 ? 2.103   28.170  -58.880 1.00 31.35  ? 260 ALA C C   1 
ATOM   9120  O  O   . ALA D 1 260 ? 1.384   28.393  -57.902 1.00 33.91  ? 260 ALA C O   1 
ATOM   9121  C  CB  . ALA D 1 260 ? 4.411   27.231  -58.547 1.00 27.20  ? 260 ALA C CB  1 
ATOM   9122  N  N   . VAL D 1 261 ? 1.624   27.725  -60.048 1.00 32.16  ? 261 VAL C N   1 
ATOM   9123  C  CA  . VAL D 1 261 ? 0.199   27.444  -60.222 1.00 27.78  ? 261 VAL C CA  1 
ATOM   9124  C  C   . VAL D 1 261 ? -0.227  26.290  -59.317 1.00 29.84  ? 261 VAL C C   1 
ATOM   9125  O  O   . VAL D 1 261 ? -1.222  26.380  -58.585 1.00 29.62  ? 261 VAL C O   1 
ATOM   9126  C  CB  . VAL D 1 261 ? -0.094  27.188  -61.714 1.00 29.11  ? 261 VAL C CB  1 
ATOM   9127  C  CG1 . VAL D 1 261 ? -1.450  26.575  -61.916 1.00 32.11  ? 261 VAL C CG1 1 
ATOM   9128  C  CG2 . VAL D 1 261 ? -0.048  28.507  -62.462 1.00 29.36  ? 261 VAL C CG2 1 
ATOM   9129  N  N   . LEU D 1 262 ? 0.571   25.229  -59.276 1.00 31.51  ? 262 LEU C N   1 
ATOM   9130  C  CA  . LEU D 1 262 ? 0.296   24.129  -58.365 1.00 29.64  ? 262 LEU C CA  1 
ATOM   9131  C  C   . LEU D 1 262 ? 0.460   24.537  -56.904 1.00 31.41  ? 262 LEU C C   1 
ATOM   9132  O  O   . LEU D 1 262 ? -0.124  23.892  -56.025 1.00 32.00  ? 262 LEU C O   1 
ATOM   9133  C  CB  . LEU D 1 262 ? 1.213   22.957  -58.697 1.00 30.98  ? 262 LEU C CB  1 
ATOM   9134  C  CG  . LEU D 1 262 ? 0.846   22.292  -60.022 1.00 34.07  ? 262 LEU C CG  1 
ATOM   9135  C  CD1 . LEU D 1 262 ? 1.879   21.263  -60.382 1.00 27.32  ? 262 LEU C CD1 1 
ATOM   9136  C  CD2 . LEU D 1 262 ? -0.533  21.652  -59.907 1.00 31.39  ? 262 LEU C CD2 1 
ATOM   9137  N  N   . ASP D 1 263 ? 1.262   25.567  -56.612 1.00 32.13  ? 263 ASP C N   1 
ATOM   9138  C  CA  . ASP D 1 263 ? 1.274   26.090  -55.248 1.00 36.02  ? 263 ASP C CA  1 
ATOM   9139  C  C   . ASP D 1 263 ? -0.047  26.788  -54.919 1.00 32.65  ? 263 ASP C C   1 
ATOM   9140  O  O   . ASP D 1 263 ? -0.648  26.533  -53.860 1.00 27.35  ? 263 ASP C O   1 
ATOM   9141  C  CB  . ASP D 1 263 ? 2.472   27.026  -55.053 1.00 38.98  ? 263 ASP C CB  1 
ATOM   9142  C  CG  . ASP D 1 263 ? 3.805   26.272  -55.029 1.00 42.10  ? 263 ASP C CG  1 
ATOM   9143  O  OD1 . ASP D 1 263 ? 3.797   25.032  -55.213 1.00 42.90  ? 263 ASP C OD1 1 
ATOM   9144  O  OD2 . ASP D 1 263 ? 4.854   26.909  -54.796 1.00 43.88  ? 263 ASP C OD2 1 
ATOM   9145  N  N   . MET D 1 264 ? -0.545  27.619  -55.849 1.00 32.68  ? 264 MET C N   1 
ATOM   9146  C  CA  . MET D 1 264 ? -1.848  28.261  -55.670 1.00 29.08  ? 264 MET C CA  1 
ATOM   9147  C  C   . MET D 1 264 ? -2.971  27.228  -55.606 1.00 27.46  ? 264 MET C C   1 
ATOM   9148  O  O   . MET D 1 264 ? -3.938  27.398  -54.853 1.00 27.66  ? 264 MET C O   1 
ATOM   9149  C  CB  . MET D 1 264 ? -2.109  29.251  -56.807 1.00 25.44  ? 264 MET C CB  1 
ATOM   9150  C  CG  . MET D 1 264 ? -3.343  30.119  -56.613 1.00 23.45  ? 264 MET C CG  1 
ATOM   9151  S  SD  . MET D 1 264 ? -3.135  31.257  -55.217 1.00 26.39  ? 264 MET C SD  1 
ATOM   9152  C  CE  . MET D 1 264 ? -2.122  32.497  -56.011 1.00 23.66  ? 264 MET C CE  1 
ATOM   9153  N  N   . CYS D 1 265 ? -2.861  26.149  -56.391 1.00 25.47  ? 265 CYS C N   1 
ATOM   9154  C  CA  . CYS D 1 265 ? -3.848  25.080  -56.306 1.00 28.73  ? 265 CYS C CA  1 
ATOM   9155  C  C   . CYS D 1 265 ? -3.894  24.484  -54.908 1.00 26.25  ? 265 CYS C C   1 
ATOM   9156  O  O   . CYS D 1 265 ? -4.967  24.124  -54.425 1.00 28.46  ? 265 CYS C O   1 
ATOM   9157  C  CB  . CYS D 1 265 ? -3.545  23.995  -57.332 1.00 34.80  ? 265 CYS C CB  1 
ATOM   9158  S  SG  . CYS D 1 265 ? -3.906  24.513  -59.000 1.00 30.64  ? 265 CYS C SG  1 
ATOM   9159  N  N   . ALA D 1 266 ? -2.736  24.372  -54.246 1.00 29.36  ? 266 ALA C N   1 
ATOM   9160  C  CA  . ALA D 1 266 ? -2.683  23.877  -52.873 1.00 33.27  ? 266 ALA C CA  1 
ATOM   9161  C  C   . ALA D 1 266 ? -3.392  24.812  -51.901 1.00 33.09  ? 266 ALA C C   1 
ATOM   9162  O  O   . ALA D 1 266 ? -4.017  24.347  -50.937 1.00 33.73  ? 266 ALA C O   1 
ATOM   9163  C  CB  . ALA D 1 266 ? -1.232  23.675  -52.437 1.00 32.52  ? 266 ALA C CB  1 
ATOM   9164  N  N   . SER D 1 267 ? -3.328  26.121  -52.142 1.00 27.57  ? 267 SER C N   1 
ATOM   9165  C  CA  . SER D 1 267 ? -4.071  27.046  -51.296 1.00 30.70  ? 267 SER C CA  1 
ATOM   9166  C  C   . SER D 1 267 ? -5.565  26.932  -51.550 1.00 29.72  ? 267 SER C C   1 
ATOM   9167  O  O   . SER D 1 267 ? -6.361  26.938  -50.605 1.00 34.42  ? 267 SER C O   1 
ATOM   9168  C  CB  . SER D 1 267 ? -3.591  28.477  -51.528 1.00 29.94  ? 267 SER C CB  1 
ATOM   9169  O  OG  . SER D 1 267 ? -2.318  28.675  -50.933 1.00 34.12  ? 267 SER C OG  1 
ATOM   9170  N  N   . LEU D 1 268 ? -5.965  26.810  -52.818 1.00 27.66  ? 268 LEU C N   1 
ATOM   9171  C  CA  . LEU D 1 268 ? -7.385  26.670  -53.120 1.00 28.21  ? 268 LEU C CA  1 
ATOM   9172  C  C   . LEU D 1 268 ? -7.920  25.372  -52.544 1.00 27.61  ? 268 LEU C C   1 
ATOM   9173  O  O   . LEU D 1 268 ? -9.027  25.330  -52.003 1.00 27.99  ? 268 LEU C O   1 
ATOM   9174  C  CB  . LEU D 1 268 ? -7.612  26.735  -54.630 1.00 22.43  ? 268 LEU C CB  1 
ATOM   9175  C  CG  . LEU D 1 268 ? -9.042  26.529  -55.133 1.00 23.22  ? 268 LEU C CG  1 
ATOM   9176  C  CD1 . LEU D 1 268 ? -9.997  27.501  -54.485 1.00 21.07  ? 268 LEU C CD1 1 
ATOM   9177  C  CD2 . LEU D 1 268 ? -9.112  26.617  -56.634 1.00 21.91  ? 268 LEU C CD2 1 
ATOM   9178  N  N   . LYS D 1 269 ? -7.131  24.308  -52.652 1.00 30.56  ? 269 LYS C N   1 
ATOM   9179  C  CA  . LYS D 1 269 ? -7.458  23.019  -52.049 1.00 33.46  ? 269 LYS C CA  1 
ATOM   9180  C  C   . LYS D 1 269 ? -7.767  23.160  -50.559 1.00 33.93  ? 269 LYS C C   1 
ATOM   9181  O  O   . LYS D 1 269 ? -8.771  22.625  -50.067 1.00 30.16  ? 269 LYS C O   1 
ATOM   9182  C  CB  . LYS D 1 269 ? -6.286  22.063  -52.295 1.00 33.89  ? 269 LYS C CB  1 
ATOM   9183  C  CG  . LYS D 1 269 ? -6.375  20.675  -51.668 1.00 43.86  ? 269 LYS C CG  1 
ATOM   9184  C  CD  . LYS D 1 269 ? -5.462  19.721  -52.455 1.00 43.07  ? 269 LYS C CD  1 
ATOM   9185  C  CE  . LYS D 1 269 ? -4.839  18.647  -51.582 1.00 47.22  ? 269 LYS C CE  1 
ATOM   9186  N  NZ  . LYS D 1 269 ? -3.657  18.005  -52.254 1.00 45.48  ? 269 LYS C NZ  1 
ATOM   9187  N  N   . GLU D 1 270 ? -6.929  23.910  -49.825 1.00 32.27  ? 270 GLU C N   1 
ATOM   9188  C  CA  . GLU D 1 270 ? -7.185  24.092  -48.395 1.00 36.93  ? 270 GLU C CA  1 
ATOM   9189  C  C   . GLU D 1 270 ? -8.387  24.996  -48.163 1.00 33.72  ? 270 GLU C C   1 
ATOM   9190  O  O   . GLU D 1 270 ? -9.191  24.745  -47.260 1.00 37.68  ? 270 GLU C O   1 
ATOM   9191  C  CB  . GLU D 1 270 ? -5.957  24.652  -47.674 1.00 37.54  ? 270 GLU C CB  1 
ATOM   9192  C  CG  . GLU D 1 270 ? -4.763  23.686  -47.592 1.00 45.30  ? 270 GLU C CG  1 
ATOM   9193  C  CD  . GLU D 1 270 ? -5.087  22.361  -46.884 1.00 53.48  ? 270 GLU C CD  1 
ATOM   9194  O  OE1 . GLU D 1 270 ? -5.651  22.392  -45.764 1.00 61.24  ? 270 GLU C OE1 1 
ATOM   9195  O  OE2 . GLU D 1 270 ? -4.762  21.285  -47.445 1.00 48.54  ? 270 GLU C OE2 1 
ATOM   9196  N  N   . LEU D 1 271 ? -8.545  26.034  -48.982 1.00 31.08  ? 271 LEU C N   1 
ATOM   9197  C  CA  . LEU D 1 271 ? -9.743  26.864  -48.886 1.00 31.94  ? 271 LEU C CA  1 
ATOM   9198  C  C   . LEU D 1 271 ? -11.009 26.028  -49.060 1.00 33.93  ? 271 LEU C C   1 
ATOM   9199  O  O   . LEU D 1 271 ? -11.966 26.169  -48.292 1.00 30.09  ? 271 LEU C O   1 
ATOM   9200  C  CB  . LEU D 1 271 ? -9.686  27.974  -49.930 1.00 25.54  ? 271 LEU C CB  1 
ATOM   9201  C  CG  . LEU D 1 271 ? -8.743  29.119  -49.559 1.00 27.27  ? 271 LEU C CG  1 
ATOM   9202  C  CD1 . LEU D 1 271 ? -8.570  30.166  -50.697 1.00 26.18  ? 271 LEU C CD1 1 
ATOM   9203  C  CD2 . LEU D 1 271 ? -9.211  29.788  -48.277 1.00 37.87  ? 271 LEU C CD2 1 
ATOM   9204  N  N   . LEU D 1 272 ? -11.023 25.132  -50.052 1.00 33.62  ? 272 LEU C N   1 
ATOM   9205  C  CA  . LEU D 1 272 ? -12.211 24.319  -50.294 1.00 31.04  ? 272 LEU C CA  1 
ATOM   9206  C  C   . LEU D 1 272 ? -12.547 23.456  -49.088 1.00 36.76  ? 272 LEU C C   1 
ATOM   9207  O  O   . LEU D 1 272 ? -13.710 23.388  -48.671 1.00 35.89  ? 272 LEU C O   1 
ATOM   9208  C  CB  . LEU D 1 272 ? -11.998 23.463  -51.545 1.00 25.72  ? 272 LEU C CB  1 
ATOM   9209  C  CG  . LEU D 1 272 ? -12.211 24.244  -52.842 1.00 28.43  ? 272 LEU C CG  1 
ATOM   9210  C  CD1 . LEU D 1 272 ? -11.769 23.469  -54.050 1.00 27.72  ? 272 LEU C CD1 1 
ATOM   9211  C  CD2 . LEU D 1 272 ? -13.700 24.541  -52.967 1.00 27.22  ? 272 LEU C CD2 1 
ATOM   9212  N  N   . GLN D 1 273 ? -11.527 22.862  -48.460 1.00 40.21  ? 273 GLN C N   1 
ATOM   9213  C  CA  . GLN D 1 273 ? -11.752 21.880  -47.406 1.00 35.11  ? 273 GLN C CA  1 
ATOM   9214  C  C   . GLN D 1 273 ? -12.027 22.517  -46.054 1.00 41.58  ? 273 GLN C C   1 
ATOM   9215  O  O   . GLN D 1 273 ? -12.806 21.962  -45.268 1.00 42.02  ? 273 GLN C O   1 
ATOM   9216  C  CB  . GLN D 1 273 ? -10.543 20.958  -47.292 1.00 35.73  ? 273 GLN C CB  1 
ATOM   9217  C  CG  . GLN D 1 273 ? -10.460 19.939  -48.407 1.00 42.71  ? 273 GLN C CG  1 
ATOM   9218  C  CD  . GLN D 1 273 ? -9.188  19.123  -48.343 1.00 48.33  ? 273 GLN C CD  1 
ATOM   9219  O  OE1 . GLN D 1 273 ? -8.146  19.615  -47.888 1.00 42.54  ? 273 GLN C OE1 1 
ATOM   9220  N  NE2 . GLN D 1 273 ? -9.263  17.860  -48.794 1.00 40.71  ? 273 GLN C NE2 1 
ATOM   9221  N  N   . ASN D 1 274 ? -11.419 23.667  -45.756 1.00 34.80  ? 274 ASN C N   1 
ATOM   9222  C  CA  . ASN D 1 274 ? -11.572 24.271  -44.439 1.00 42.20  ? 274 ASN C CA  1 
ATOM   9223  C  C   . ASN D 1 274 ? -12.373 25.564  -44.445 1.00 36.93  ? 274 ASN C C   1 
ATOM   9224  O  O   . ASN D 1 274 ? -12.510 26.187  -43.389 1.00 41.01  ? 274 ASN C O   1 
ATOM   9225  C  CB  . ASN D 1 274 ? -10.202 24.545  -43.795 1.00 48.54  ? 274 ASN C CB  1 
ATOM   9226  C  CG  . ASN D 1 274 ? -9.272  23.348  -43.836 1.00 38.31  ? 274 ASN C CG  1 
ATOM   9227  O  OD1 . ASN D 1 274 ? -9.702  22.217  -43.996 1.00 45.05  ? 274 ASN C OD1 1 
ATOM   9228  N  ND2 . ASN D 1 274 ? -7.983  23.601  -43.674 1.00 46.77  ? 274 ASN C ND2 1 
ATOM   9229  N  N   . GLY D 1 275 ? -12.907 25.985  -45.585 1.00 38.48  ? 275 GLY C N   1 
ATOM   9230  C  CA  . GLY D 1 275 ? -13.613 27.252  -45.611 1.00 34.43  ? 275 GLY C CA  1 
ATOM   9231  C  C   . GLY D 1 275 ? -12.676 28.430  -45.391 1.00 35.78  ? 275 GLY C C   1 
ATOM   9232  O  O   . GLY D 1 275 ? -11.447 28.316  -45.435 1.00 35.00  ? 275 GLY C O   1 
ATOM   9233  N  N   . MET D 1 276 ? -13.286 29.591  -45.143 1.00 42.77  ? 276 MET C N   1 
ATOM   9234  C  CA  . MET D 1 276 ? -12.534 30.835  -45.016 1.00 41.16  ? 276 MET C CA  1 
ATOM   9235  C  C   . MET D 1 276 ? -12.408 31.331  -43.582 1.00 41.19  ? 276 MET C C   1 
ATOM   9236  O  O   . MET D 1 276 ? -11.704 32.321  -43.348 1.00 47.40  ? 276 MET C O   1 
ATOM   9237  C  CB  . MET D 1 276 ? -13.166 31.930  -45.893 1.00 42.29  ? 276 MET C CB  1 
ATOM   9238  C  CG  . MET D 1 276 ? -12.940 31.702  -47.376 1.00 39.14  ? 276 MET C CG  1 
ATOM   9239  S  SD  . MET D 1 276 ? -13.408 33.077  -48.449 1.00 50.24  ? 276 MET C SD  1 
ATOM   9240  C  CE  . MET D 1 276 ? -12.423 34.396  -47.802 1.00 36.56  ? 276 MET C CE  1 
ATOM   9241  N  N   . ASN D 1 277 ? -13.038 30.664  -42.614 1.00 45.13  ? 277 ASN C N   1 
ATOM   9242  C  CA  . ASN D 1 277 ? -12.841 30.969  -41.194 1.00 47.85  ? 277 ASN C CA  1 
ATOM   9243  C  C   . ASN D 1 277 ? -13.168 32.426  -40.892 1.00 45.51  ? 277 ASN C C   1 
ATOM   9244  O  O   . ASN D 1 277 ? -12.415 33.128  -40.212 1.00 42.14  ? 277 ASN C O   1 
ATOM   9245  C  CB  . ASN D 1 277 ? -11.417 30.638  -40.745 1.00 48.74  ? 277 ASN C CB  1 
ATOM   9246  C  CG  . ASN D 1 277 ? -11.155 29.161  -40.720 1.00 49.37  ? 277 ASN C CG  1 
ATOM   9247  O  OD1 . ASN D 1 277 ? -12.005 28.378  -40.291 1.00 51.74  ? 277 ASN C OD1 1 
ATOM   9248  N  ND2 . ASN D 1 277 ? -9.974  28.764  -41.167 1.00 50.97  ? 277 ASN C ND2 1 
ATOM   9249  N  N   . GLY D 1 278 ? -14.298 32.882  -41.429 1.00 51.25  ? 278 GLY C N   1 
ATOM   9250  C  CA  . GLY D 1 278 ? -14.757 34.239  -41.239 1.00 37.46  ? 278 GLY C CA  1 
ATOM   9251  C  C   . GLY D 1 278 ? -13.918 35.312  -41.888 1.00 42.33  ? 278 GLY C C   1 
ATOM   9252  O  O   . GLY D 1 278 ? -14.221 36.492  -41.697 1.00 52.46  ? 278 GLY C O   1 
ATOM   9253  N  N   . ARG D 1 279 ? -12.877 34.959  -42.649 1.00 46.41  ? 279 ARG C N   1 
ATOM   9254  C  CA  . ARG D 1 279 ? -12.072 35.959  -43.342 1.00 45.58  ? 279 ARG C CA  1 
ATOM   9255  C  C   . ARG D 1 279 ? -12.668 36.267  -44.720 1.00 40.96  ? 279 ARG C C   1 
ATOM   9256  O  O   . ARG D 1 279 ? -13.622 35.631  -45.166 1.00 40.60  ? 279 ARG C O   1 
ATOM   9257  C  CB  . ARG D 1 279 ? -10.616 35.500  -43.464 1.00 39.78  ? 279 ARG C CB  1 
ATOM   9258  C  CG  . ARG D 1 279 ? -9.774  35.958  -42.275 1.00 38.45  ? 279 ARG C CG  1 
ATOM   9259  C  CD  . ARG D 1 279 ? -8.426  35.288  -42.205 1.00 37.18  ? 279 ARG C CD  1 
ATOM   9260  N  NE  . ARG D 1 279 ? -8.539  33.838  -42.214 1.00 39.58  ? 279 ARG C NE  1 
ATOM   9261  C  CZ  . ARG D 1 279 ? -7.508  33.009  -42.286 1.00 39.34  ? 279 ARG C CZ  1 
ATOM   9262  N  NH1 . ARG D 1 279 ? -6.261  33.454  -42.296 1.00 37.33  ? 279 ARG C NH1 1 
ATOM   9263  N  NH2 . ARG D 1 279 ? -7.735  31.700  -42.389 1.00 47.27  ? 279 ARG C NH2 1 
ATOM   9264  N  N   . THR D 1 280 ? -12.115 37.276  -45.389 1.00 36.90  ? 280 THR C N   1 
ATOM   9265  C  CA  . THR D 1 280 ? -12.559 37.605  -46.736 1.00 36.28  ? 280 THR C CA  1 
ATOM   9266  C  C   . THR D 1 280 ? -11.358 37.739  -47.664 1.00 32.66  ? 280 THR C C   1 
ATOM   9267  O  O   . THR D 1 280 ? -10.222 37.965  -47.235 1.00 34.52  ? 280 THR C O   1 
ATOM   9268  C  CB  . THR D 1 280 ? -13.396 38.910  -46.806 1.00 34.95  ? 280 THR C CB  1 
ATOM   9269  O  OG1 . THR D 1 280 ? -12.551 40.055  -46.607 1.00 33.50  ? 280 THR C OG1 1 
ATOM   9270  C  CG2 . THR D 1 280 ? -14.515 38.894  -45.767 1.00 31.59  ? 280 THR C CG2 1 
ATOM   9271  N  N   . ILE D 1 281 ? -11.643 37.643  -48.957 1.00 27.48  ? 281 ILE C N   1 
ATOM   9272  C  CA  . ILE D 1 281 ? -10.647 37.795  -50.005 1.00 30.17  ? 281 ILE C CA  1 
ATOM   9273  C  C   . ILE D 1 281 ? -11.219 38.784  -50.992 1.00 29.13  ? 281 ILE C C   1 
ATOM   9274  O  O   . ILE D 1 281 ? -12.286 38.535  -51.566 1.00 27.94  ? 281 ILE C O   1 
ATOM   9275  C  CB  . ILE D 1 281 ? -10.314 36.485  -50.729 1.00 25.43  ? 281 ILE C CB  1 
ATOM   9276  C  CG1 . ILE D 1 281 ? -9.769  35.430  -49.780 1.00 27.76  ? 281 ILE C CG1 1 
ATOM   9277  C  CG2 . ILE D 1 281 ? -9.299  36.759  -51.813 1.00 26.64  ? 281 ILE C CG2 1 
ATOM   9278  C  CD1 . ILE D 1 281 ? -9.529  34.107  -50.472 1.00 27.81  ? 281 ILE C CD1 1 
ATOM   9279  N  N   . LEU D 1 282 ? -10.536 39.913  -51.161 1.00 28.45  ? 282 LEU C N   1 
ATOM   9280  C  CA  . LEU D 1 282 ? -11.029 40.991  -52.009 1.00 29.22  ? 282 LEU C CA  1 
ATOM   9281  C  C   . LEU D 1 282 ? -12.468 41.339  -51.640 1.00 24.40  ? 282 LEU C C   1 
ATOM   9282  O  O   . LEU D 1 282 ? -13.334 41.508  -52.497 1.00 25.34  ? 282 LEU C O   1 
ATOM   9283  C  CB  . LEU D 1 282 ? -10.893 40.632  -53.487 1.00 27.51  ? 282 LEU C CB  1 
ATOM   9284  C  CG  . LEU D 1 282 ? -9.422  40.548  -53.882 1.00 29.06  ? 282 LEU C CG  1 
ATOM   9285  C  CD1 . LEU D 1 282 ? -9.236  40.027  -55.290 1.00 24.37  ? 282 LEU C CD1 1 
ATOM   9286  C  CD2 . LEU D 1 282 ? -8.777  41.924  -53.700 1.00 27.01  ? 282 LEU C CD2 1 
ATOM   9287  N  N   . GLY D 1 283 ? -12.727 41.415  -50.341 1.00 30.83  ? 283 GLY C N   1 
ATOM   9288  C  CA  . GLY D 1 283 ? -14.029 41.825  -49.858 1.00 32.84  ? 283 GLY C CA  1 
ATOM   9289  C  C   . GLY D 1 283 ? -15.134 40.830  -50.111 1.00 32.61  ? 283 GLY C C   1 
ATOM   9290  O  O   . GLY D 1 283 ? -16.309 41.209  -50.104 1.00 37.01  ? 283 GLY C O   1 
ATOM   9291  N  N   . SER D 1 284 ? -14.798 39.568  -50.334 1.00 29.20  ? 284 SER C N   1 
ATOM   9292  C  CA  . SER D 1 284 ? -15.793 38.559  -50.645 1.00 30.17  ? 284 SER C CA  1 
ATOM   9293  C  C   . SER D 1 284 ? -15.645 37.393  -49.674 1.00 30.62  ? 284 SER C C   1 
ATOM   9294  O  O   . SER D 1 284 ? -14.528 37.029  -49.305 1.00 29.45  ? 284 SER C O   1 
ATOM   9295  C  CB  . SER D 1 284 ? -15.642 38.093  -52.096 1.00 28.47  ? 284 SER C CB  1 
ATOM   9296  O  OG  . SER D 1 284 ? -16.610 37.115  -52.420 1.00 40.16  ? 284 SER C OG  1 
ATOM   9297  N  N   . ALA D 1 285 ? -16.772 36.842  -49.226 1.00 26.00  ? 285 ALA C N   1 
ATOM   9298  C  CA  . ALA D 1 285 ? -16.772 35.685  -48.339 1.00 30.62  ? 285 ALA C CA  1 
ATOM   9299  C  C   . ALA D 1 285 ? -16.910 34.356  -49.083 1.00 37.61  ? 285 ALA C C   1 
ATOM   9300  O  O   . ALA D 1 285 ? -16.904 33.295  -48.444 1.00 34.11  ? 285 ALA C O   1 
ATOM   9301  C  CB  . ALA D 1 285 ? -17.883 35.816  -47.299 1.00 34.26  ? 285 ALA C CB  1 
ATOM   9302  N  N   . LEU D 1 286 ? -17.044 34.378  -50.407 1.00 32.59  ? 286 LEU C N   1 
ATOM   9303  C  CA  . LEU D 1 286 ? -17.024 33.156  -51.193 1.00 33.06  ? 286 LEU C CA  1 
ATOM   9304  C  C   . LEU D 1 286 ? -16.018 33.294  -52.331 1.00 32.99  ? 286 LEU C C   1 
ATOM   9305  O  O   . LEU D 1 286 ? -15.482 34.374  -52.595 1.00 33.42  ? 286 LEU C O   1 
ATOM   9306  C  CB  . LEU D 1 286 ? -18.420 32.796  -51.720 1.00 29.31  ? 286 LEU C CB  1 
ATOM   9307  C  CG  . LEU D 1 286 ? -19.371 33.851  -52.276 1.00 34.15  ? 286 LEU C CG  1 
ATOM   9308  C  CD1 . LEU D 1 286 ? -18.967 34.364  -53.663 1.00 38.01  ? 286 LEU C CD1 1 
ATOM   9309  C  CD2 . LEU D 1 286 ? -20.768 33.249  -52.301 1.00 38.92  ? 286 LEU C CD2 1 
ATOM   9310  N  N   . LEU D 1 287 ? -15.774 32.180  -53.017 1.00 31.40  ? 287 LEU C N   1 
ATOM   9311  C  CA  . LEU D 1 287 ? -14.769 32.119  -54.068 1.00 29.23  ? 287 LEU C CA  1 
ATOM   9312  C  C   . LEU D 1 287 ? -15.364 32.582  -55.394 1.00 28.64  ? 287 LEU C C   1 
ATOM   9313  O  O   . LEU D 1 287 ? -16.265 31.933  -55.931 1.00 28.45  ? 287 LEU C O   1 
ATOM   9314  C  CB  . LEU D 1 287 ? -14.215 30.700  -54.168 1.00 29.53  ? 287 LEU C CB  1 
ATOM   9315  C  CG  . LEU D 1 287 ? -13.590 30.237  -52.842 1.00 29.87  ? 287 LEU C CG  1 
ATOM   9316  C  CD1 . LEU D 1 287 ? -13.154 28.783  -52.863 1.00 21.71  ? 287 LEU C CD1 1 
ATOM   9317  C  CD2 . LEU D 1 287 ? -12.412 31.159  -52.499 1.00 33.07  ? 287 LEU C CD2 1 
ATOM   9318  N  N   . GLU D 1 288 ? -14.844 33.698  -55.924 1.00 29.43  ? 288 GLU C N   1 
ATOM   9319  C  CA  . GLU D 1 288 ? -15.361 34.305  -57.148 1.00 25.65  ? 288 GLU C CA  1 
ATOM   9320  C  C   . GLU D 1 288 ? -14.813 33.602  -58.385 1.00 21.34  ? 288 GLU C C   1 
ATOM   9321  O  O   . GLU D 1 288 ? -13.606 33.378  -58.509 1.00 24.49  ? 288 GLU C O   1 
ATOM   9322  C  CB  . GLU D 1 288 ? -15.013 35.791  -57.200 1.00 30.55  ? 288 GLU C CB  1 
ATOM   9323  C  CG  . GLU D 1 288 ? -15.916 36.677  -56.366 1.00 38.93  ? 288 GLU C CG  1 
ATOM   9324  C  CD  . GLU D 1 288 ? -17.279 36.886  -57.018 1.00 46.56  ? 288 GLU C CD  1 
ATOM   9325  O  OE1 . GLU D 1 288 ? -17.403 36.644  -58.248 1.00 37.36  ? 288 GLU C OE1 1 
ATOM   9326  O  OE2 . GLU D 1 288 ? -18.214 37.313  -56.301 1.00 52.91  ? 288 GLU C OE2 1 
ATOM   9327  N  N   . ASP D 1 289 ? -15.699 33.249  -59.304 1.00 22.58  ? 289 ASP C N   1 
ATOM   9328  C  CA  . ASP D 1 289 ? -15.270 32.557  -60.513 1.00 26.18  ? 289 ASP C CA  1 
ATOM   9329  C  C   . ASP D 1 289 ? -15.696 33.275  -61.795 1.00 26.41  ? 289 ASP C C   1 
ATOM   9330  O  O   . ASP D 1 289 ? -15.725 32.658  -62.867 1.00 27.74  ? 289 ASP C O   1 
ATOM   9331  C  CB  . ASP D 1 289 ? -15.766 31.108  -60.498 1.00 21.88  ? 289 ASP C CB  1 
ATOM   9332  C  CG  . ASP D 1 289 ? -17.238 30.983  -60.793 1.00 26.06  ? 289 ASP C CG  1 
ATOM   9333  O  OD1 . ASP D 1 289 ? -17.987 31.967  -60.617 1.00 26.91  ? 289 ASP C OD1 1 
ATOM   9334  O  OD2 . ASP D 1 289 ? -17.658 29.869  -61.193 1.00 37.51  ? 289 ASP C OD2 1 
ATOM   9335  N  N   . GLU D 1 290 ? -16.021 34.565  -61.734 1.00 21.72  ? 290 GLU C N   1 
ATOM   9336  C  CA  . GLU D 1 290 ? -16.406 35.271  -62.952 1.00 26.01  ? 290 GLU C CA  1 
ATOM   9337  C  C   . GLU D 1 290 ? -15.379 36.338  -63.326 1.00 27.35  ? 290 GLU C C   1 
ATOM   9338  O  O   . GLU D 1 290 ? -15.728 37.374  -63.899 1.00 18.67  ? 290 GLU C O   1 
ATOM   9339  C  CB  . GLU D 1 290 ? -17.815 35.853  -62.837 1.00 23.91  ? 290 GLU C CB  1 
ATOM   9340  C  CG  . GLU D 1 290 ? -18.846 34.727  -62.823 1.00 33.05  ? 290 GLU C CG  1 
ATOM   9341  C  CD  . GLU D 1 290 ? -20.282 35.133  -63.137 1.00 37.94  ? 290 GLU C CD  1 
ATOM   9342  O  OE1 . GLU D 1 290 ? -20.589 36.351  -63.223 1.00 33.64  ? 290 GLU C OE1 1 
ATOM   9343  O  OE2 . GLU D 1 290 ? -21.109 34.188  -63.293 1.00 36.24  ? 290 GLU C OE2 1 
ATOM   9344  N  N   . PHE D 1 291 ? -14.109 36.064  -63.010 1.00 23.35  ? 291 PHE C N   1 
ATOM   9345  C  CA  . PHE D 1 291 ? -12.944 36.785  -63.517 1.00 23.12  ? 291 PHE C CA  1 
ATOM   9346  C  C   . PHE D 1 291 ? -12.070 35.809  -64.290 1.00 26.11  ? 291 PHE C C   1 
ATOM   9347  O  O   . PHE D 1 291 ? -11.506 34.875  -63.707 1.00 23.33  ? 291 PHE C O   1 
ATOM   9348  C  CB  . PHE D 1 291 ? -12.133 37.413  -62.388 1.00 26.64  ? 291 PHE C CB  1 
ATOM   9349  C  CG  . PHE D 1 291 ? -12.837 38.539  -61.664 1.00 28.46  ? 291 PHE C CG  1 
ATOM   9350  C  CD1 . PHE D 1 291 ? -12.877 39.824  -62.216 1.00 25.07  ? 291 PHE C CD1 1 
ATOM   9351  C  CD2 . PHE D 1 291 ? -13.379 38.341  -60.403 1.00 26.94  ? 291 PHE C CD2 1 
ATOM   9352  C  CE1 . PHE D 1 291 ? -13.506 40.888  -61.537 1.00 25.54  ? 291 PHE C CE1 1 
ATOM   9353  C  CE2 . PHE D 1 291 ? -14.001 39.389  -59.717 1.00 27.90  ? 291 PHE C CE2 1 
ATOM   9354  C  CZ  . PHE D 1 291 ? -14.053 40.674  -60.290 1.00 23.62  ? 291 PHE C CZ  1 
ATOM   9355  N  N   . THR D 1 292 ? -11.937 36.025  -65.592 1.00 28.47  ? 292 THR C N   1 
ATOM   9356  C  CA  . THR D 1 292 ? -11.007 35.228  -66.372 1.00 28.44  ? 292 THR C CA  1 
ATOM   9357  C  C   . THR D 1 292 ? -9.580  35.649  -66.041 1.00 26.46  ? 292 THR C C   1 
ATOM   9358  O  O   . THR D 1 292 ? -9.355  36.674  -65.391 1.00 25.48  ? 292 THR C O   1 
ATOM   9359  C  CB  . THR D 1 292 ? -11.309 35.351  -67.872 1.00 28.52  ? 292 THR C CB  1 
ATOM   9360  O  OG1 . THR D 1 292 ? -10.974 36.667  -68.354 1.00 26.83  ? 292 THR C OG1 1 
ATOM   9361  C  CG2 . THR D 1 292 ? -12.786 35.021  -68.152 1.00 24.82  ? 292 THR C CG2 1 
ATOM   9362  N  N   . PRO D 1 293 ? -8.592  34.834  -66.422 1.00 29.57  ? 293 PRO C N   1 
ATOM   9363  C  CA  . PRO D 1 293 ? -7.197  35.270  -66.276 1.00 27.22  ? 293 PRO C CA  1 
ATOM   9364  C  C   . PRO D 1 293 ? -6.877  36.534  -67.060 1.00 30.60  ? 293 PRO C C   1 
ATOM   9365  O  O   . PRO D 1 293 ? -6.068  37.346  -66.596 1.00 30.10  ? 293 PRO C O   1 
ATOM   9366  C  CB  . PRO D 1 293 ? -6.411  34.058  -66.792 1.00 29.19  ? 293 PRO C CB  1 
ATOM   9367  C  CG  . PRO D 1 293 ? -7.329  32.890  -66.561 1.00 25.71  ? 293 PRO C CG  1 
ATOM   9368  C  CD  . PRO D 1 293 ? -8.695  33.413  -66.825 1.00 26.55  ? 293 PRO C CD  1 
ATOM   9369  N  N   . PHE D 1 294 ? -7.495  36.728  -68.228 1.00 28.15  ? 294 PHE C N   1 
ATOM   9370  C  CA  . PHE D 1 294 ? -7.333  37.974  -68.969 1.00 30.19  ? 294 PHE C CA  1 
ATOM   9371  C  C   . PHE D 1 294 ? -7.969  39.141  -68.225 1.00 34.73  ? 294 PHE C C   1 
ATOM   9372  O  O   . PHE D 1 294 ? -7.434  40.257  -68.247 1.00 35.10  ? 294 PHE C O   1 
ATOM   9373  C  CB  . PHE D 1 294 ? -7.935  37.835  -70.370 1.00 34.61  ? 294 PHE C CB  1 
ATOM   9374  C  CG  . PHE D 1 294 ? -8.014  39.142  -71.155 1.00 45.17  ? 294 PHE C CG  1 
ATOM   9375  C  CD1 . PHE D 1 294 ? -9.083  40.030  -70.974 1.00 50.68  ? 294 PHE C CD1 1 
ATOM   9376  C  CD2 . PHE D 1 294 ? -7.041  39.468  -72.087 1.00 44.71  ? 294 PHE C CD2 1 
ATOM   9377  C  CE1 . PHE D 1 294 ? -9.158  41.224  -71.687 1.00 50.53  ? 294 PHE C CE1 1 
ATOM   9378  C  CE2 . PHE D 1 294 ? -7.117  40.650  -72.813 1.00 50.34  ? 294 PHE C CE2 1 
ATOM   9379  C  CZ  . PHE D 1 294 ? -8.177  41.527  -72.612 1.00 55.90  ? 294 PHE C CZ  1 
ATOM   9380  N  N   . ASP D 1 295 ? -9.143  38.921  -67.619 1.00 29.24  ? 295 ASP C N   1 
ATOM   9381  C  CA  . ASP D 1 295 ? -9.779  39.972  -66.828 1.00 31.19  ? 295 ASP C CA  1 
ATOM   9382  C  C   . ASP D 1 295 ? -8.835  40.472  -65.743 1.00 31.17  ? 295 ASP C C   1 
ATOM   9383  O  O   . ASP D 1 295 ? -8.706  41.681  -65.531 1.00 31.92  ? 295 ASP C O   1 
ATOM   9384  C  CB  . ASP D 1 295 ? -11.082 39.474  -66.199 1.00 29.75  ? 295 ASP C CB  1 
ATOM   9385  C  CG  . ASP D 1 295 ? -12.111 39.064  -67.226 1.00 35.93  ? 295 ASP C CG  1 
ATOM   9386  O  OD1 . ASP D 1 295 ? -11.884 39.350  -68.426 1.00 35.85  ? 295 ASP C OD1 1 
ATOM   9387  O  OD2 . ASP D 1 295 ? -13.145 38.456  -66.835 1.00 30.43  ? 295 ASP C OD2 1 
ATOM   9388  N  N   . VAL D 1 296 ? -8.179  39.547  -65.032 1.00 32.67  ? 296 VAL C N   1 
ATOM   9389  C  CA  . VAL D 1 296 ? -7.258  39.941  -63.968 1.00 29.78  ? 296 VAL C CA  1 
ATOM   9390  C  C   . VAL D 1 296 ? -6.127  40.777  -64.542 1.00 32.12  ? 296 VAL C C   1 
ATOM   9391  O  O   . VAL D 1 296 ? -5.847  41.881  -64.063 1.00 31.34  ? 296 VAL C O   1 
ATOM   9392  C  CB  . VAL D 1 296 ? -6.709  38.713  -63.223 1.00 27.72  ? 296 VAL C CB  1 
ATOM   9393  C  CG1 . VAL D 1 296 ? -5.664  39.158  -62.213 1.00 21.54  ? 296 VAL C CG1 1 
ATOM   9394  C  CG2 . VAL D 1 296 ? -7.830  37.949  -62.535 1.00 25.18  ? 296 VAL C CG2 1 
ATOM   9395  N  N   . VAL D 1 297 ? -5.445  40.249  -65.561 1.00 30.41  ? 297 VAL C N   1 
ATOM   9396  C  CA  . VAL D 1 297 ? -4.350  40.984  -66.185 1.00 31.41  ? 297 VAL C CA  1 
ATOM   9397  C  C   . VAL D 1 297 ? -4.830  42.352  -66.653 1.00 27.68  ? 297 VAL C C   1 
ATOM   9398  O  O   . VAL D 1 297 ? -4.223  43.372  -66.324 1.00 33.44  ? 297 VAL C O   1 
ATOM   9399  C  CB  . VAL D 1 297 ? -3.733  40.172  -67.344 1.00 27.81  ? 297 VAL C CB  1 
ATOM   9400  C  CG1 . VAL D 1 297 ? -2.797  41.053  -68.164 1.00 27.26  ? 297 VAL C CG1 1 
ATOM   9401  C  CG2 . VAL D 1 297 ? -2.949  38.979  -66.812 1.00 25.97  ? 297 VAL C CG2 1 
ATOM   9402  N  N   . ARG D 1 298 ? -5.961  42.394  -67.370 1.00 31.50  ? 298 ARG C N   1 
ATOM   9403  C  CA  . ARG D 1 298 ? -6.482  43.653  -67.911 1.00 33.38  ? 298 ARG C CA  1 
ATOM   9404  C  C   . ARG D 1 298 ? -6.712  44.687  -66.813 1.00 37.51  ? 298 ARG C C   1 
ATOM   9405  O  O   . ARG D 1 298 ? -6.207  45.819  -66.883 1.00 28.86  ? 298 ARG C O   1 
ATOM   9406  C  CB  . ARG D 1 298 ? -7.792  43.405  -68.672 1.00 36.07  ? 298 ARG C CB  1 
ATOM   9407  C  CG  . ARG D 1 298 ? -8.502  44.690  -69.153 1.00 37.81  ? 298 ARG C CG  1 
ATOM   9408  C  CD  . ARG D 1 298 ? -9.803  44.432  -69.938 1.00 43.35  ? 298 ARG C CD  1 
ATOM   9409  N  NE  . ARG D 1 298 ? -10.910 43.938  -69.111 1.00 55.64  ? 298 ARG C NE  1 
ATOM   9410  C  CZ  . ARG D 1 298 ? -11.860 44.698  -68.565 1.00 52.97  ? 298 ARG C CZ  1 
ATOM   9411  N  NH1 . ARG D 1 298 ? -11.874 46.013  -68.724 1.00 48.37  ? 298 ARG C NH1 1 
ATOM   9412  N  NH2 . ARG D 1 298 ? -12.833 44.122  -67.853 1.00 41.95  ? 298 ARG C NH2 1 
ATOM   9413  N  N   . GLN D 1 299 ? -7.450  44.306  -65.769 1.00 33.86  ? 299 GLN C N   1 
ATOM   9414  C  CA  . GLN D 1 299 ? -7.780  45.286  -64.745 1.00 28.87  ? 299 GLN C CA  1 
ATOM   9415  C  C   . GLN D 1 299 ? -6.551  45.705  -63.956 1.00 32.89  ? 299 GLN C C   1 
ATOM   9416  O  O   . GLN D 1 299 ? -6.409  46.881  -63.608 1.00 34.73  ? 299 GLN C O   1 
ATOM   9417  C  CB  . GLN D 1 299 ? -8.831  44.739  -63.792 1.00 26.85  ? 299 GLN C CB  1 
ATOM   9418  C  CG  . GLN D 1 299 ? -9.206  45.780  -62.783 1.00 25.38  ? 299 GLN C CG  1 
ATOM   9419  C  CD  . GLN D 1 299 ? -10.266 45.336  -61.844 1.00 26.63  ? 299 GLN C CD  1 
ATOM   9420  O  OE1 . GLN D 1 299 ? -10.423 45.919  -60.774 1.00 27.84  ? 299 GLN C OE1 1 
ATOM   9421  N  NE2 . GLN D 1 299 ? -11.004 44.300  -62.216 1.00 22.16  ? 299 GLN C NE2 1 
ATOM   9422  N  N   . CYS D 1 300 ? -5.641  44.766  -63.683 1.00 35.82  ? 300 CYS C N   1 
ATOM   9423  C  CA  . CYS D 1 300 ? -4.491  45.050  -62.840 1.00 35.23  ? 300 CYS C CA  1 
ATOM   9424  C  C   . CYS D 1 300 ? -3.365  45.753  -63.583 1.00 35.34  ? 300 CYS C C   1 
ATOM   9425  O  O   . CYS D 1 300 ? -2.438  46.243  -62.936 1.00 37.68  ? 300 CYS C O   1 
ATOM   9426  C  CB  . CYS D 1 300 ? -3.974  43.751  -62.213 1.00 36.53  ? 300 CYS C CB  1 
ATOM   9427  S  SG  . CYS D 1 300 ? -5.085  43.045  -60.951 1.00 39.06  ? 300 CYS C SG  1 
ATOM   9428  N  N   . SER D 1 301 ? -3.437  45.851  -64.911 1.00 32.92  ? 301 SER C N   1 
ATOM   9429  C  CA  . SER D 1 301 ? -2.404  46.518  -65.691 1.00 36.45  ? 301 SER C CA  1 
ATOM   9430  C  C   . SER D 1 301 ? -2.845  47.852  -66.279 1.00 37.65  ? 301 SER C C   1 
ATOM   9431  O  O   . SER D 1 301 ? -1.984  48.638  -66.680 1.00 44.65  ? 301 SER C O   1 
ATOM   9432  C  CB  . SER D 1 301 ? -1.903  45.601  -66.824 1.00 33.69  ? 301 SER C CB  1 
ATOM   9433  O  OG  . SER D 1 301 ? -2.704  45.699  -67.990 1.00 35.25  ? 301 SER C OG  1 
ATOM   9434  N  N   . GLY D 1 302 ? -4.148  48.126  -66.350 1.00 38.78  ? 302 GLY C N   1 
ATOM   9435  C  CA  . GLY D 1 302 ? -4.624  49.430  -66.775 1.00 38.41  ? 302 GLY C CA  1 
ATOM   9436  C  C   . GLY D 1 302 ? -4.960  49.574  -68.242 1.00 35.16  ? 302 GLY C C   1 
ATOM   9437  O  O   . GLY D 1 302 ? -4.851  50.679  -68.785 1.00 32.85  ? 302 GLY C O   1 
ATOM   9438  N  N   . VAL D 1 303 ? -5.400  48.500  -68.896 1.00 34.84  ? 303 VAL C N   1 
ATOM   9439  C  CA  . VAL D 1 303 ? -5.698  48.541  -70.323 1.00 36.38  ? 303 VAL C CA  1 
ATOM   9440  C  C   . VAL D 1 303 ? -6.889  49.461  -70.589 1.00 39.79  ? 303 VAL C C   1 
ATOM   9441  O  O   . VAL D 1 303 ? -7.876  49.470  -69.839 1.00 37.58  ? 303 VAL C O   1 
ATOM   9442  C  CB  . VAL D 1 303 ? -5.929  47.107  -70.836 1.00 28.88  ? 303 VAL C CB  1 
ATOM   9443  C  CG1 . VAL D 1 303 ? -6.580  47.095  -72.206 1.00 29.16  ? 303 VAL C CG1 1 
ATOM   9444  C  CG2 . VAL D 1 303 ? -4.605  46.376  -70.869 1.00 28.68  ? 303 VAL C CG2 1 
ATOM   9445  N  N   . THR D 1 304 ? -6.785  50.270  -71.645 1.00 34.41  ? 304 THR C N   1 
ATOM   9446  C  CA  . THR D 1 304 ? -7.795  51.259  -72.007 1.00 34.93  ? 304 THR C CA  1 
ATOM   9447  C  C   . THR D 1 304 ? -8.381  50.948  -73.387 1.00 41.26  ? 304 THR C C   1 
ATOM   9448  O  O   . THR D 1 304 ? -7.971  50.002  -74.064 1.00 41.45  ? 304 THR C O   1 
ATOM   9449  C  CB  . THR D 1 304 ? -7.200  52.671  -71.952 1.00 40.92  ? 304 THR C CB  1 
ATOM   9450  O  OG1 . THR D 1 304 ? -6.098  52.775  -72.866 1.00 44.14  ? 304 THR C OG1 1 
ATOM   9451  C  CG2 . THR D 1 304 ? -6.697  52.971  -70.548 1.00 33.15  ? 304 THR C CG2 1 
ATOM   9452  N  N   . PHE D 1 305 ? -9.387  51.736  -73.782 1.00 47.65  ? 305 PHE C N   1 
ATOM   9453  C  CA  . PHE D 1 305 ? -10.054 51.564  -75.087 1.00 48.30  ? 305 PHE C CA  1 
ATOM   9454  C  C   . PHE D 1 305 ? -10.344 52.906  -75.767 1.00 42.61  ? 305 PHE C C   1 
ATOM   9455  O  O   . PHE D 1 305 ? -10.344 53.003  -76.996 1.00 46.90  ? 305 PHE C O   1 
ATOM   9456  C  CB  . PHE D 1 305 ? -11.352 50.769  -74.921 1.00 45.77  ? 305 PHE C CB  1 
ATOM   9457  C  CG  . PHE D 1 305 ? -11.190 49.558  -74.063 1.00 43.21  ? 305 PHE C CG  1 
ATOM   9458  C  CD1 . PHE D 1 305 ? -10.580 48.418  -74.562 1.00 40.72  ? 305 PHE C CD1 1 
ATOM   9459  C  CD2 . PHE D 1 305 ? -11.609 49.575  -72.744 1.00 35.87  ? 305 PHE C CD2 1 
ATOM   9460  C  CE1 . PHE D 1 305 ? -10.401 47.315  -73.767 1.00 41.33  ? 305 PHE C CE1 1 
ATOM   9461  C  CE2 . PHE D 1 305 ? -11.434 48.471  -71.942 1.00 42.85  ? 305 PHE C CE2 1 
ATOM   9462  C  CZ  . PHE D 1 305 ? -10.822 47.342  -72.452 1.00 45.55  ? 305 PHE C CZ  1 
HETATM 9463  O  O26 . O6K E 2 .   ? 0.334   22.035  -6.703  1.00 35.31  ? 401 O6K A O26 1 
HETATM 9464  C  C24 . O6K E 2 .   ? -0.794  21.976  -7.052  1.00 27.84  ? 401 O6K A C24 1 
HETATM 9465  O  O25 . O6K E 2 .   ? -1.654  20.918  -6.697  1.00 29.83  ? 401 O6K A O25 1 
HETATM 9466  C  C27 . O6K E 2 .   ? -1.510  20.264  -5.440  1.00 32.97  ? 401 O6K A C27 1 
HETATM 9467  C  C31 . O6K E 2 .   ? -0.196  19.465  -5.426  1.00 31.36  ? 401 O6K A C31 1 
HETATM 9468  C  C32 . O6K E 2 .   ? -2.639  19.219  -5.353  1.00 34.22  ? 401 O6K A C32 1 
HETATM 9469  C  C33 . O6K E 2 .   ? -1.564  21.217  -4.220  1.00 31.17  ? 401 O6K A C33 1 
HETATM 9470  N  N23 . O6K E 2 .   ? -1.351  23.039  -7.874  1.00 32.26  ? 401 O6K A N23 1 
HETATM 9471  C  C19 . O6K E 2 .   ? -0.539  23.979  -8.658  1.00 26.35  ? 401 O6K A C19 1 
HETATM 9472  C  C21 . O6K E 2 .   ? -1.299  24.722  -9.685  1.00 24.07  ? 401 O6K A C21 1 
HETATM 9473  O  O22 . O6K E 2 .   ? -2.663  24.459  -9.822  1.00 22.59  ? 401 O6K A O22 1 
HETATM 9474  C  C18 . O6K E 2 .   ? 0.843   24.210  -8.484  1.00 24.51  ? 401 O6K A C18 1 
HETATM 9475  C  C17 . O6K E 2 .   ? 1.515   25.181  -9.330  1.00 24.84  ? 401 O6K A C17 1 
HETATM 9476  C  C16 . O6K E 2 .   ? 0.785   25.918  -10.337 1.00 24.46  ? 401 O6K A C16 1 
HETATM 9477  N  N15 . O6K E 2 .   ? -0.647  25.663  -10.496 1.00 25.95  ? 401 O6K A N15 1 
HETATM 9478  C  C20 . O6K E 2 .   ? -1.469  26.336  -11.477 1.00 24.38  ? 401 O6K A C20 1 
HETATM 9479  C  C22 . O6K E 2 .   ? -0.968  27.752  -11.784 1.00 21.55  ? 401 O6K A C22 1 
HETATM 9480  C  C29 . O6K E 2 .   ? -1.250  28.620  -10.514 1.00 27.43  ? 401 O6K A C29 1 
HETATM 9481  C  C34 . O6K E 2 .   ? -2.659  29.226  -10.382 1.00 21.07  ? 401 O6K A C34 1 
HETATM 9482  C  C30 . O6K E 2 .   ? -1.466  30.124  -10.765 1.00 28.07  ? 401 O6K A C30 1 
HETATM 9483  C  C36 . O6K E 2 .   ? -1.468  25.458  -12.716 1.00 23.40  ? 401 O6K A C36 1 
HETATM 9484  O  O37 . O6K E 2 .   ? -0.538  24.788  -13.017 1.00 27.00  ? 401 O6K A O37 1 
HETATM 9485  N  N38 . O6K E 2 .   ? -2.682  25.427  -13.526 1.00 20.66  ? 401 O6K A N38 1 
HETATM 9486  C  C40 . O6K E 2 .   ? -2.673  24.613  -14.714 1.00 26.92  ? 401 O6K A C40 1 
HETATM 9487  C  C42 . O6K E 2 .   ? -3.817  23.566  -14.626 1.00 24.74  ? 401 O6K A C42 1 
HETATM 9488  C  C45 . O6K E 2 .   ? -3.486  22.456  -13.539 1.00 25.69  ? 401 O6K A C45 1 
HETATM 9489  C  C47 . O6K E 2 .   ? -4.579  21.428  -13.372 1.00 27.25  ? 401 O6K A C47 1 
HETATM 9490  O  O48 . O6K E 2 .   ? -5.731  21.636  -13.097 1.00 22.00  ? 401 O6K A O48 1 
HETATM 9491  N  N49 . O6K E 2 .   ? -3.993  20.089  -13.573 1.00 27.75  ? 401 O6K A N49 1 
HETATM 9492  C  C51 . O6K E 2 .   ? -2.495  20.216  -13.895 1.00 29.82  ? 401 O6K A C51 1 
HETATM 9493  C  C54 . O6K E 2 .   ? -2.202  21.771  -13.943 1.00 27.41  ? 401 O6K A C54 1 
HETATM 9494  C  C57 . O6K E 2 .   ? -2.834  25.712  -15.782 1.00 28.93  ? 401 O6K A C57 1 
HETATM 9495  O  O40 . O6K E 2 .   ? -1.948  26.805  -15.562 1.00 33.96  ? 401 O6K A O40 1 
HETATM 9496  C  C35 . O6K E 2 .   ? -2.729  25.136  -17.204 1.00 28.17  ? 401 O6K A C35 1 
HETATM 9497  O  O41 . O6K E 2 .   ? -3.632  24.465  -17.579 1.00 32.04  ? 401 O6K A O41 1 
HETATM 9498  N  N36 . O6K E 2 .   ? -1.617  25.351  -18.150 1.00 30.33  ? 401 O6K A N36 1 
HETATM 9499  C  C13 . O6K E 2 .   ? -0.376  26.090  -17.950 1.00 34.99  ? 401 O6K A C13 1 
HETATM 9500  C  C14 . O6K E 2 .   ? 0.676   25.000  -18.253 1.00 42.26  ? 401 O6K A C14 1 
HETATM 9501  C  C28 . O6K E 2 .   ? 1.083   24.789  -19.502 1.00 43.57  ? 401 O6K A C28 1 
HETATM 9502  C  C26 . O6K E 2 .   ? 2.121   23.686  -19.777 1.00 43.68  ? 401 O6K A C26 1 
HETATM 9503  C  C25 . O6K E 2 .   ? 2.578   22.930  -18.781 1.00 43.32  ? 401 O6K A C25 1 
HETATM 9504  C  C23 . O6K E 2 .   ? 2.085   23.154  -17.340 1.00 42.09  ? 401 O6K A C23 1 
HETATM 9505  C  C15 . O6K E 2 .   ? 1.193   24.111  -17.098 1.00 42.03  ? 401 O6K A C15 1 
HETATM 9506  CL CL  . CL  F 3 .   ? 0.344   39.980  -35.692 1.00 33.32  ? 402 CL  A CL  1 
HETATM 9507  O  O26 . O6K G 2 .   ? -42.086 -0.493  -26.666 1.00 37.12  ? 401 O6K B O26 1 
HETATM 9508  C  C24 . O6K G 2 .   ? -40.913 -0.334  -26.611 1.00 33.99  ? 401 O6K B C24 1 
HETATM 9509  O  O25 . O6K G 2 .   ? -40.205 -0.153  -25.401 1.00 44.32  ? 401 O6K B O25 1 
HETATM 9510  C  C27 . O6K G 2 .   ? -40.555 -0.900  -24.246 1.00 40.64  ? 401 O6K B C27 1 
HETATM 9511  C  C31 . O6K G 2 .   ? -41.935 -0.465  -23.708 1.00 35.89  ? 401 O6K B C31 1 
HETATM 9512  C  C32 . O6K G 2 .   ? -39.482 -0.582  -23.181 1.00 38.74  ? 401 O6K B C32 1 
HETATM 9513  C  C33 . O6K G 2 .   ? -40.535 -2.410  -24.574 1.00 37.82  ? 401 O6K B C33 1 
HETATM 9514  N  N23 . O6K G 2 .   ? -40.112 -0.265  -27.821 1.00 27.47  ? 401 O6K B N23 1 
HETATM 9515  C  C19 . O6K G 2 .   ? -40.666 0.236   -29.073 1.00 29.33  ? 401 O6K B C19 1 
HETATM 9516  C  C21 . O6K G 2 .   ? -39.820 1.115   -29.927 1.00 28.96  ? 401 O6K B C21 1 
HETATM 9517  O  O22 . O6K G 2 .   ? -38.525 1.492   -29.539 1.00 27.17  ? 401 O6K B O22 1 
HETATM 9518  C  C18 . O6K G 2 .   ? -41.961 -0.120  -29.493 1.00 35.46  ? 401 O6K B C18 1 
HETATM 9519  C  C17 . O6K G 2 .   ? -42.480 0.382   -30.754 1.00 34.76  ? 401 O6K B C17 1 
HETATM 9520  C  C16 . O6K G 2 .   ? -41.671 1.237   -31.580 1.00 30.57  ? 401 O6K B C16 1 
HETATM 9521  N  N15 . O6K G 2 .   ? -40.328 1.586   -31.139 1.00 28.80  ? 401 O6K B N15 1 
HETATM 9522  C  C20 . O6K G 2 .   ? -39.444 2.414   -31.921 1.00 26.44  ? 401 O6K B C20 1 
HETATM 9523  C  C22 . O6K G 2 .   ? -39.783 2.344   -33.411 1.00 23.88  ? 401 O6K B C22 1 
HETATM 9524  C  C29 . O6K G 2 .   ? -39.450 0.935   -33.978 1.00 27.14  ? 401 O6K B C29 1 
HETATM 9525  C  C34 . O6K G 2 .   ? -38.007 0.734   -34.441 1.00 26.17  ? 401 O6K B C34 1 
HETATM 9526  C  C30 . O6K G 2 .   ? -39.135 0.903   -35.477 1.00 30.48  ? 401 O6K B C30 1 
HETATM 9527  C  C36 . O6K G 2 .   ? -39.585 3.848   -31.470 1.00 27.75  ? 401 O6K B C36 1 
HETATM 9528  O  O37 . O6K G 2 .   ? -40.634 4.272   -31.140 1.00 34.53  ? 401 O6K B O37 1 
HETATM 9529  N  N38 . O6K G 2 .   ? -38.386 4.690   -31.474 1.00 26.83  ? 401 O6K B N38 1 
HETATM 9530  C  C40 . O6K G 2 .   ? -38.534 6.074   -31.083 1.00 28.28  ? 401 O6K B C40 1 
HETATM 9531  C  C42 . O6K G 2 .   ? -37.561 6.350   -29.944 1.00 28.80  ? 401 O6K B C42 1 
HETATM 9532  C  C45 . O6K G 2 .   ? -37.995 5.523   -28.692 1.00 30.71  ? 401 O6K B C45 1 
HETATM 9533  C  C47 . O6K G 2 .   ? -36.883 5.579   -27.718 1.00 28.66  ? 401 O6K B C47 1 
HETATM 9534  O  O48 . O6K G 2 .   ? -35.762 5.243   -27.930 1.00 28.25  ? 401 O6K B O48 1 
HETATM 9535  N  N49 . O6K G 2 .   ? -37.408 6.110   -26.457 1.00 32.40  ? 401 O6K B N49 1 
HETATM 9536  C  C51 . O6K G 2 .   ? -38.900 6.444   -26.584 1.00 25.36  ? 401 O6K B C51 1 
HETATM 9537  C  C54 . O6K G 2 .   ? -39.246 6.131   -28.094 1.00 32.42  ? 401 O6K B C54 1 
HETATM 9538  C  C57 . O6K G 2 .   ? -38.113 6.806   -32.348 1.00 30.89  ? 401 O6K B C57 1 
HETATM 9539  O  O40 . O6K G 2 .   ? -38.858 6.309   -33.426 1.00 33.75  ? 401 O6K B O40 1 
HETATM 9540  C  C35 . O6K G 2 .   ? -38.185 8.344   -32.180 1.00 30.79  ? 401 O6K B C35 1 
HETATM 9541  O  O41 . O6K G 2 .   ? -37.337 8.874   -31.532 1.00 35.45  ? 401 O6K B O41 1 
HETATM 9542  N  N36 . O6K G 2 .   ? -39.169 9.262   -32.765 1.00 30.49  ? 401 O6K B N36 1 
HETATM 9543  C  C13 . O6K G 2 .   ? -40.336 8.989   -33.582 1.00 34.25  ? 401 O6K B C13 1 
HETATM 9544  C  C14 . O6K G 2 .   ? -41.447 9.675   -32.750 1.00 33.85  ? 401 O6K B C14 1 
HETATM 9545  C  C28 . O6K G 2 .   ? -41.685 10.971  -32.892 1.00 36.35  ? 401 O6K B C28 1 
HETATM 9546  C  C26 . O6K G 2 .   ? -42.783 11.651  -32.054 1.00 36.85  ? 401 O6K B C26 1 
HETATM 9547  C  C25 . O6K G 2 .   ? -43.495 10.949  -31.184 1.00 30.79  ? 401 O6K B C25 1 
HETATM 9548  C  C23 . O6K G 2 .   ? -43.212 9.449   -31.019 1.00 35.90  ? 401 O6K B C23 1 
HETATM 9549  C  C15 . O6K G 2 .   ? -42.262 8.863   -31.737 1.00 30.09  ? 401 O6K B C15 1 
HETATM 9550  O  O26 . O6K H 2 .   ? 1.320   56.339  -50.467 1.00 35.42  ? 401 O6K D O26 1 
HETATM 9551  C  C24 . O6K H 2 .   ? 0.226   56.114  -50.872 1.00 34.50  ? 401 O6K D C24 1 
HETATM 9552  O  O25 . O6K H 2 .   ? -0.416  54.855  -50.789 1.00 40.77  ? 401 O6K D O25 1 
HETATM 9553  C  C27 . O6K H 2 .   ? -0.304  54.137  -49.561 1.00 35.61  ? 401 O6K D C27 1 
HETATM 9554  C  C31 . O6K H 2 .   ? 1.132   53.649  -49.275 1.00 30.72  ? 401 O6K D C31 1 
HETATM 9555  C  C32 . O6K H 2 .   ? -1.222  52.908  -49.692 1.00 36.32  ? 401 O6K D C32 1 
HETATM 9556  C  C33 . O6K H 2 .   ? -0.833  55.013  -48.392 1.00 35.12  ? 401 O6K D C33 1 
HETATM 9557  N  N23 . O6K H 2 .   ? -0.549  57.138  -51.545 1.00 33.41  ? 401 O6K D N23 1 
HETATM 9558  C  C19 . O6K H 2 .   ? -0.001  58.285  -52.261 1.00 29.02  ? 401 O6K D C19 1 
HETATM 9559  C  C21 . O6K H 2 .   ? -0.914  58.931  -53.223 1.00 24.76  ? 401 O6K D C21 1 
HETATM 9560  O  O22 . O6K H 2 .   ? -2.204  58.454  -53.421 1.00 26.46  ? 401 O6K D O22 1 
HETATM 9561  C  C18 . O6K H 2 .   ? 1.298   58.782  -52.077 1.00 36.97  ? 401 O6K D C18 1 
HETATM 9562  C  C17 . O6K H 2 .   ? 1.739   59.940  -52.841 1.00 36.29  ? 401 O6K D C17 1 
HETATM 9563  C  C16 . O6K H 2 .   ? 0.841   60.567  -53.777 1.00 29.23  ? 401 O6K D C16 1 
HETATM 9564  N  N15 . O6K H 2 .   ? -0.499  60.036  -53.939 1.00 23.74  ? 401 O6K D N15 1 
HETATM 9565  C  C20 . O6K H 2 .   ? -1.488  60.573  -54.842 1.00 26.97  ? 401 O6K D C20 1 
HETATM 9566  C  C22 . O6K H 2 .   ? -1.234  62.054  -55.140 1.00 24.61  ? 401 O6K D C22 1 
HETATM 9567  C  C29 . O6K H 2 .   ? -1.510  62.872  -53.844 1.00 27.61  ? 401 O6K D C29 1 
HETATM 9568  C  C34 . O6K H 2 .   ? -2.960  63.325  -53.599 1.00 25.12  ? 401 O6K D C34 1 
HETATM 9569  C  C30 . O6K H 2 .   ? -1.884  64.344  -54.044 1.00 33.88  ? 401 O6K D C30 1 
HETATM 9570  C  C36 . O6K H 2 .   ? -1.431  59.686  -56.086 1.00 26.73  ? 401 O6K D C36 1 
HETATM 9571  O  O37 . O6K H 2 .   ? -0.503  58.998  -56.326 1.00 24.14  ? 401 O6K D O37 1 
HETATM 9572  N  N38 . O6K H 2 .   ? -2.598  59.680  -56.962 1.00 24.99  ? 401 O6K D N38 1 
HETATM 9573  C  C40 . O6K H 2 .   ? -2.585  58.866  -58.149 1.00 27.14  ? 401 O6K D C40 1 
HETATM 9574  C  C42 . O6K H 2 .   ? -3.667  57.780  -58.018 1.00 22.97  ? 401 O6K D C42 1 
HETATM 9575  C  C45 . O6K H 2 .   ? -3.157  56.683  -57.001 1.00 27.79  ? 401 O6K D C45 1 
HETATM 9576  C  C47 . O6K H 2 .   ? -4.120  55.553  -56.891 1.00 28.20  ? 401 O6K D C47 1 
HETATM 9577  O  O48 . O6K H 2 .   ? -5.278  55.645  -56.648 1.00 30.58  ? 401 O6K D O48 1 
HETATM 9578  N  N49 . O6K H 2 .   ? -3.404  54.298  -57.115 1.00 28.56  ? 401 O6K D N49 1 
HETATM 9579  C  C51 . O6K H 2 .   ? -1.930  54.583  -57.400 1.00 28.52  ? 401 O6K D C51 1 
HETATM 9580  C  C54 . O6K H 2 .   ? -1.798  56.155  -57.414 1.00 28.39  ? 401 O6K D C54 1 
HETATM 9581  C  C57 . O6K H 2 .   ? -2.888  59.920  -59.221 1.00 29.98  ? 401 O6K D C57 1 
HETATM 9582  O  O40 . O6K H 2 .   ? -2.064  61.053  -58.990 1.00 31.91  ? 401 O6K D O40 1 
HETATM 9583  C  C35 . O6K H 2 .   ? -2.823  59.345  -60.660 1.00 24.23  ? 401 O6K D C35 1 
HETATM 9584  O  O41 . O6K H 2 .   ? -3.741  58.717  -61.065 1.00 31.67  ? 401 O6K D O41 1 
HETATM 9585  N  N36 . O6K H 2 .   ? -1.745  59.536  -61.638 1.00 30.37  ? 401 O6K D N36 1 
HETATM 9586  C  C13 . O6K H 2 .   ? -0.502  60.242  -61.404 1.00 28.96  ? 401 O6K D C13 1 
HETATM 9587  C  C14 . O6K H 2 .   ? 0.623   59.266  -61.799 1.00 25.04  ? 401 O6K D C14 1 
HETATM 9588  C  C28 . O6K H 2 .   ? 0.984   59.207  -63.068 1.00 29.40  ? 401 O6K D C28 1 
HETATM 9589  C  C26 . O6K H 2 .   ? 2.098   58.263  -63.510 1.00 27.47  ? 401 O6K D C26 1 
HETATM 9590  C  C25 . O6K H 2 .   ? 2.702   57.510  -62.607 1.00 36.65  ? 401 O6K D C25 1 
HETATM 9591  C  C23 . O6K H 2 .   ? 2.286   57.575  -61.125 1.00 35.28  ? 401 O6K D C23 1 
HETATM 9592  C  C15 . O6K H 2 .   ? 1.317   58.398  -60.748 1.00 34.31  ? 401 O6K D C15 1 
HETATM 9593  CL CL  . CL  I 3 .   ? -1.890  74.369  -79.254 0.81 35.98  ? 402 CL  D CL  1 
HETATM 9594  O  O26 . O6K J 2 .   ? -41.173 31.079  -67.598 1.00 40.98  ? 401 O6K C O26 1 
HETATM 9595  C  C24 . O6K J 2 .   ? -40.106 31.590  -67.523 1.00 35.39  ? 401 O6K C C24 1 
HETATM 9596  O  O25 . O6K J 2 .   ? -39.302 31.540  -66.352 1.00 41.25  ? 401 O6K C O25 1 
HETATM 9597  C  C27 . O6K J 2 .   ? -39.446 30.482  -65.413 1.00 34.93  ? 401 O6K C C27 1 
HETATM 9598  C  C31 . O6K J 2 .   ? -40.795 30.646  -64.680 1.00 34.42  ? 401 O6K C C31 1 
HETATM 9599  C  C32 . O6K J 2 .   ? -38.345 30.666  -64.351 1.00 40.01  ? 401 O6K C C32 1 
HETATM 9600  C  C33 . O6K J 2 .   ? -39.356 29.083  -66.075 1.00 32.54  ? 401 O6K C C33 1 
HETATM 9601  N  N23 . O6K J 2 .   ? -39.548 32.253  -68.697 1.00 31.13  ? 401 O6K C N23 1 
HETATM 9602  C  C19 . O6K J 2 .   ? -40.377 32.784  -69.788 1.00 28.10  ? 401 O6K C C19 1 
HETATM 9603  C  C21 . O6K J 2 .   ? -39.638 33.515  -70.834 1.00 33.04  ? 401 O6K C C21 1 
HETATM 9604  O  O22 . O6K J 2 .   ? -38.259 33.654  -70.685 1.00 31.22  ? 401 O6K C O22 1 
HETATM 9605  C  C18 . O6K J 2 .   ? -41.770 32.641  -69.903 1.00 30.00  ? 401 O6K C C18 1 
HETATM 9606  C  C17 . O6K J 2 .   ? -42.464 33.214  -71.043 1.00 32.12  ? 401 O6K C C17 1 
HETATM 9607  C  C16 . O6K J 2 .   ? -41.740 33.928  -72.065 1.00 25.67  ? 401 O6K C C16 1 
HETATM 9608  N  N15 . O6K J 2 .   ? -40.299 34.052  -71.942 1.00 30.24  ? 401 O6K C N15 1 
HETATM 9609  C  C20 . O6K J 2 .   ? -39.481 34.769  -72.895 1.00 30.51  ? 401 O6K C C20 1 
HETATM 9610  C  C22 . O6K J 2 .   ? -40.012 34.719  -74.335 1.00 30.03  ? 401 O6K C C22 1 
HETATM 9611  C  C29 . O6K J 2 .   ? -39.611 33.394  -75.040 1.00 32.79  ? 401 O6K C C29 1 
HETATM 9612  C  C34 . O6K J 2 .   ? -38.217 33.355  -75.697 1.00 34.67  ? 401 O6K C C34 1 
HETATM 9613  C  C30 . O6K J 2 .   ? -39.475 33.470  -76.576 1.00 34.76  ? 401 O6K C C30 1 
HETATM 9614  C  C36 . O6K J 2 .   ? -39.556 36.210  -72.413 1.00 29.25  ? 401 O6K C C36 1 
HETATM 9615  O  O37 . O6K J 2 .   ? -40.596 36.684  -72.090 1.00 33.30  ? 401 O6K C O37 1 
HETATM 9616  N  N38 . O6K J 2 .   ? -38.328 37.005  -72.333 1.00 27.72  ? 401 O6K C N38 1 
HETATM 9617  C  C40 . O6K J 2 .   ? -38.456 38.392  -71.904 1.00 32.60  ? 401 O6K C C40 1 
HETATM 9618  C  C42 . O6K J 2 .   ? -37.377 38.682  -70.847 1.00 29.06  ? 401 O6K C C42 1 
HETATM 9619  C  C45 . O6K J 2 .   ? -37.665 37.749  -69.613 1.00 31.84  ? 401 O6K C C45 1 
HETATM 9620  C  C47 . O6K J 2 .   ? -36.530 37.733  -68.658 1.00 31.05  ? 401 O6K C C47 1 
HETATM 9621  O  O48 . O6K J 2 .   ? -35.409 37.438  -68.919 1.00 30.45  ? 401 O6K C O48 1 
HETATM 9622  N  N49 . O6K J 2 .   ? -37.030 38.128  -67.332 1.00 33.30  ? 401 O6K C N49 1 
HETATM 9623  C  C51 . O6K J 2 .   ? -38.531 38.419  -67.403 1.00 30.34  ? 401 O6K C C51 1 
HETATM 9624  C  C54 . O6K J 2 .   ? -38.913 38.245  -68.924 1.00 32.79  ? 401 O6K C C54 1 
HETATM 9625  C  C57 . O6K J 2 .   ? -38.288 39.194  -73.211 1.00 36.80  ? 401 O6K C C57 1 
HETATM 9626  O  O40 . O6K J 2 .   ? -39.173 38.700  -74.190 1.00 35.57  ? 401 O6K C O40 1 
HETATM 9627  C  C35 . O6K J 2 .   ? -38.488 40.708  -72.984 1.00 35.02  ? 401 O6K C C35 1 
HETATM 9628  O  O41 . O6K J 2 .   ? -37.630 41.280  -72.402 1.00 34.57  ? 401 O6K C O41 1 
HETATM 9629  N  N36 . O6K J 2 .   ? -39.626 41.531  -73.455 1.00 41.97  ? 401 O6K C N36 1 
HETATM 9630  C  C13 . O6K J 2 .   ? -40.854 41.158  -74.168 1.00 45.62  ? 401 O6K C C13 1 
HETATM 9631  C  C14 . O6K J 2 .   ? -41.895 41.743  -73.189 1.00 57.53  ? 401 O6K C C14 1 
HETATM 9632  C  C28 . O6K J 2 .   ? -42.230 43.025  -73.280 1.00 60.37  ? 401 O6K C C28 1 
HETATM 9633  C  C26 . O6K J 2 .   ? -43.243 43.625  -72.292 1.00 62.51  ? 401 O6K C C26 1 
HETATM 9634  C  C25 . O6K J 2 .   ? -43.778 42.863  -71.346 1.00 60.59  ? 401 O6K C C25 1 
HETATM 9635  C  C23 . O6K J 2 .   ? -43.385 41.380  -71.231 1.00 60.17  ? 401 O6K C C23 1 
HETATM 9636  C  C15 . O6K J 2 .   ? -42.506 40.861  -72.082 1.00 61.82  ? 401 O6K C C15 1 
HETATM 9637  CL CL  . CL  K 3 .   ? -41.116 55.603  -91.554 1.00 35.96  ? 402 CL  C CL  1 
HETATM 9638  O  O   . HOH L 4 .   ? 9.034   34.343  -13.577 1.00 61.94  ? 501 HOH A O   1 
HETATM 9639  O  O   . HOH L 4 .   ? -20.482 20.509  -1.722  1.00 26.45  ? 502 HOH A O   1 
HETATM 9640  O  O   . HOH L 4 .   ? -22.895 13.136  -8.322  1.00 38.83  ? 503 HOH A O   1 
HETATM 9641  O  O   . HOH L 4 .   ? 6.694   29.457  -26.384 1.00 35.16  ? 504 HOH A O   1 
HETATM 9642  O  O   . HOH L 4 .   ? -41.888 6.055   -13.022 1.00 40.88  ? 505 HOH A O   1 
HETATM 9643  O  O   . HOH L 4 .   ? -17.696 41.226  -12.149 1.00 40.58  ? 506 HOH A O   1 
HETATM 9644  O  O   . HOH L 4 .   ? 5.260   33.582  -19.988 1.00 35.62  ? 507 HOH A O   1 
HETATM 9645  O  O   . HOH L 4 .   ? -19.089 20.868  -13.033 1.00 44.45  ? 508 HOH A O   1 
HETATM 9646  O  O   . HOH L 4 .   ? -33.611 26.570  -21.295 1.00 38.03  ? 509 HOH A O   1 
HETATM 9647  O  O   . HOH L 4 .   ? -35.065 9.104   -20.157 1.00 33.14  ? 510 HOH A O   1 
HETATM 9648  O  O   . HOH L 4 .   ? -33.401 2.710   9.390   1.00 37.91  ? 511 HOH A O   1 
HETATM 9649  O  O   . HOH L 4 .   ? -13.347 25.554  -22.869 1.00 20.75  ? 512 HOH A O   1 
HETATM 9650  O  O   . HOH L 4 .   ? -44.244 15.131  7.466   1.00 28.16  ? 513 HOH A O   1 
HETATM 9651  O  O   . HOH L 4 .   ? -18.929 39.787  -32.300 1.00 22.52  ? 514 HOH A O   1 
HETATM 9652  O  O   . HOH L 4 .   ? -39.651 8.590   8.860   1.00 33.05  ? 515 HOH A O   1 
HETATM 9653  O  O   . HOH L 4 .   ? 0.581   39.323  -30.604 1.00 30.93  ? 516 HOH A O   1 
HETATM 9654  O  O   . HOH L 4 .   ? -30.007 0.664   -11.280 1.00 23.57  ? 517 HOH A O   1 
HETATM 9655  O  O   . HOH L 4 .   ? -8.794  16.789  -19.437 1.00 25.88  ? 518 HOH A O   1 
HETATM 9656  O  O   . HOH L 4 .   ? -49.642 11.147  -4.061  1.00 33.18  ? 519 HOH A O   1 
HETATM 9657  O  O   . HOH L 4 .   ? 11.698  34.482  -12.391 1.00 56.13  ? 520 HOH A O   1 
HETATM 9658  O  O   . HOH L 4 .   ? -21.940 36.696  -33.443 1.00 30.57  ? 521 HOH A O   1 
HETATM 9659  O  O   . HOH L 4 .   ? -7.606  14.985  -17.620 1.00 44.47  ? 522 HOH A O   1 
HETATM 9660  O  O   . HOH L 4 .   ? -26.328 17.626  -14.607 1.00 31.45  ? 523 HOH A O   1 
HETATM 9661  O  O   . HOH L 4 .   ? -28.051 14.708  -8.342  1.00 18.12  ? 524 HOH A O   1 
HETATM 9662  O  O   . HOH L 4 .   ? -26.734 25.119  -12.919 1.00 27.79  ? 525 HOH A O   1 
HETATM 9663  O  O   . HOH L 4 .   ? -38.282 23.914  -9.321  1.00 27.04  ? 526 HOH A O   1 
HETATM 9664  O  O   . HOH L 4 .   ? 3.450   45.540  -29.021 1.00 24.68  ? 527 HOH A O   1 
HETATM 9665  O  O   . HOH L 4 .   ? -38.634 20.467  -9.229  1.00 36.79  ? 528 HOH A O   1 
HETATM 9666  O  O   . HOH L 4 .   ? -36.317 21.919  15.767  1.00 20.74  ? 529 HOH A O   1 
HETATM 9667  O  O   . HOH L 4 .   ? -17.753 19.173  -9.323  1.00 28.10  ? 530 HOH A O   1 
HETATM 9668  O  O   . HOH L 4 .   ? -0.687  31.363  -29.588 1.00 28.33  ? 531 HOH A O   1 
HETATM 9669  O  O   . HOH L 4 .   ? -14.163 40.073  -17.678 1.00 27.19  ? 532 HOH A O   1 
HETATM 9670  O  O   . HOH L 4 .   ? -16.162 40.089  -25.245 1.00 27.05  ? 533 HOH A O   1 
HETATM 9671  O  O   . HOH L 4 .   ? -0.836  36.926  -31.952 1.00 25.76  ? 534 HOH A O   1 
HETATM 9672  O  O   . HOH L 4 .   ? -39.083 23.771  12.975  1.00 44.26  ? 535 HOH A O   1 
HETATM 9673  O  O   . HOH L 4 .   ? -13.113 27.790  -7.373  1.00 22.23  ? 536 HOH A O   1 
HETATM 9674  O  O   . HOH L 4 .   ? -43.814 7.760   8.688   1.00 35.95  ? 537 HOH A O   1 
HETATM 9675  O  O   . HOH L 4 .   ? -46.530 11.071  -1.340  1.00 34.24  ? 538 HOH A O   1 
HETATM 9676  O  O   . HOH L 4 .   ? -42.091 21.546  4.422   1.00 36.96  ? 539 HOH A O   1 
HETATM 9677  O  O   . HOH L 4 .   ? -2.812  24.881  -23.531 1.00 22.90  ? 540 HOH A O   1 
HETATM 9678  O  O   . HOH L 4 .   ? 6.681   24.321  -16.570 1.00 38.13  ? 541 HOH A O   1 
HETATM 9679  O  O   . HOH L 4 .   ? 4.892   25.704  -11.405 1.00 36.31  ? 542 HOH A O   1 
HETATM 9680  O  O   . HOH L 4 .   ? -4.832  46.334  -16.181 1.00 32.86  ? 543 HOH A O   1 
HETATM 9681  O  O   . HOH L 4 .   ? -42.025 7.008   1.593   1.00 33.14  ? 544 HOH A O   1 
HETATM 9682  O  O   . HOH L 4 .   ? 1.407   21.690  -13.315 1.00 38.77  ? 545 HOH A O   1 
HETATM 9683  O  O   . HOH L 4 .   ? 2.431   28.000  1.219   1.00 37.10  ? 546 HOH A O   1 
HETATM 9684  O  O   . HOH L 4 .   ? -30.038 33.245  -20.056 1.00 38.63  ? 547 HOH A O   1 
HETATM 9685  O  O   . HOH L 4 .   ? -45.600 6.276   8.044   1.00 51.09  ? 548 HOH A O   1 
HETATM 9686  O  O   . HOH L 4 .   ? -36.380 26.545  5.660   1.00 33.82  ? 549 HOH A O   1 
HETATM 9687  O  O   . HOH L 4 .   ? -29.309 23.386  -13.530 1.00 34.03  ? 550 HOH A O   1 
HETATM 9688  O  O   . HOH L 4 .   ? -38.838 11.277  -18.778 1.00 32.63  ? 551 HOH A O   1 
HETATM 9689  O  O   . HOH L 4 .   ? -16.847 22.567  -33.971 1.00 31.43  ? 552 HOH A O   1 
HETATM 9690  O  O   . HOH L 4 .   ? -28.877 25.117  -17.229 1.00 30.34  ? 553 HOH A O   1 
HETATM 9691  O  O   . HOH L 4 .   ? 6.698   38.688  -9.888  1.00 33.21  ? 554 HOH A O   1 
HETATM 9692  O  O   . HOH L 4 .   ? -1.331  48.789  -26.180 1.00 36.60  ? 555 HOH A O   1 
HETATM 9693  O  O   . HOH L 4 .   ? -37.727 7.198   6.971   1.00 37.25  ? 556 HOH A O   1 
HETATM 9694  O  O   . HOH L 4 .   ? -24.230 0.694   -13.895 1.00 32.21  ? 557 HOH A O   1 
HETATM 9695  O  O   . HOH L 4 .   ? -24.070 36.514  -12.044 1.00 33.13  ? 558 HOH A O   1 
HETATM 9696  O  O   . HOH L 4 .   ? 3.249   46.431  -7.983  1.00 36.87  ? 559 HOH A O   1 
HETATM 9697  O  O   . HOH L 4 .   ? -24.875 1.421   0.579   1.00 29.01  ? 560 HOH A O   1 
HETATM 9698  O  O   . HOH L 4 .   ? -41.373 19.693  7.658   1.00 25.84  ? 561 HOH A O   1 
HETATM 9699  O  O   . HOH L 4 .   ? -24.287 38.684  -25.760 1.00 28.11  ? 562 HOH A O   1 
HETATM 9700  O  O   . HOH L 4 .   ? -4.536  33.587  -13.234 1.00 18.01  ? 563 HOH A O   1 
HETATM 9701  O  O   . HOH L 4 .   ? -28.922 22.611  -6.550  1.00 28.55  ? 564 HOH A O   1 
HETATM 9702  O  O   . HOH L 4 .   ? -30.422 26.619  -18.809 1.00 32.38  ? 565 HOH A O   1 
HETATM 9703  O  O   . HOH L 4 .   ? -23.100 38.031  -28.822 1.00 23.90  ? 566 HOH A O   1 
HETATM 9704  O  O   . HOH L 4 .   ? -33.918 26.024  -24.211 1.00 30.96  ? 567 HOH A O   1 
HETATM 9705  O  O   . HOH L 4 .   ? -4.127  49.699  -30.912 1.00 29.21  ? 568 HOH A O   1 
HETATM 9706  O  O   . HOH L 4 .   ? 1.414   47.137  -25.679 1.00 31.56  ? 569 HOH A O   1 
HETATM 9707  O  O   . HOH L 4 .   ? -33.109 33.099  -31.110 1.00 34.43  ? 570 HOH A O   1 
HETATM 9708  O  O   . HOH L 4 .   ? -1.882  48.014  -21.979 1.00 31.26  ? 571 HOH A O   1 
HETATM 9709  O  O   . HOH L 4 .   ? -45.769 14.512  5.552   1.00 23.16  ? 572 HOH A O   1 
HETATM 9710  O  O   . HOH L 4 .   ? -29.626 16.558  -17.228 1.00 28.68  ? 573 HOH A O   1 
HETATM 9711  O  O   . HOH L 4 .   ? -21.302 14.788  -18.703 1.00 26.26  ? 574 HOH A O   1 
HETATM 9712  O  O   . HOH L 4 .   ? -0.266  40.497  -8.129  1.00 31.07  ? 575 HOH A O   1 
HETATM 9713  O  O   . HOH L 4 .   ? -44.261 17.037  0.915   1.00 28.91  ? 576 HOH A O   1 
HETATM 9714  O  O   . HOH L 4 .   ? -36.972 22.766  -26.302 1.00 34.44  ? 577 HOH A O   1 
HETATM 9715  O  O   . HOH L 4 .   ? -5.973  35.602  -6.666  1.00 26.10  ? 578 HOH A O   1 
HETATM 9716  O  O   . HOH L 4 .   ? -26.845 16.407  -16.380 1.00 27.42  ? 579 HOH A O   1 
HETATM 9717  O  O   . HOH L 4 .   ? -36.110 28.468  3.068   1.00 31.22  ? 580 HOH A O   1 
HETATM 9718  O  O   . HOH L 4 .   ? -20.725 13.519  -3.962  1.00 38.80  ? 581 HOH A O   1 
HETATM 9719  O  O   . HOH L 4 .   ? -18.620 38.947  -10.577 1.00 41.90  ? 582 HOH A O   1 
HETATM 9720  O  O   . HOH L 4 .   ? -5.102  41.341  -39.091 1.00 39.12  ? 583 HOH A O   1 
HETATM 9721  O  O   . HOH L 4 .   ? -6.040  42.523  -10.710 1.00 27.36  ? 584 HOH A O   1 
HETATM 9722  O  O   . HOH L 4 .   ? -0.236  40.724  -32.723 1.00 25.44  ? 585 HOH A O   1 
HETATM 9723  O  O   . HOH L 4 .   ? -24.381 6.219   4.543   1.00 42.63  ? 586 HOH A O   1 
HETATM 9724  O  O   . HOH L 4 .   ? -47.724 13.427  -13.955 1.00 33.90  ? 587 HOH A O   1 
HETATM 9725  O  O   . HOH L 4 .   ? 5.231   48.345  -7.961  1.00 37.89  ? 588 HOH A O   1 
HETATM 9726  O  O   . HOH L 4 .   ? -43.275 21.168  -2.561  1.00 34.05  ? 589 HOH A O   1 
HETATM 9727  O  O   . HOH L 4 .   ? -21.838 12.107  -6.765  1.00 45.97  ? 590 HOH A O   1 
HETATM 9728  O  O   . HOH L 4 .   ? -0.175  45.392  -34.326 1.00 26.26  ? 591 HOH A O   1 
HETATM 9729  O  O   . HOH L 4 .   ? 1.651   31.382  -31.430 1.00 37.23  ? 592 HOH A O   1 
HETATM 9730  O  O   . HOH L 4 .   ? -22.521 32.734  -35.266 1.00 45.41  ? 593 HOH A O   1 
HETATM 9731  O  O   . HOH L 4 .   ? -19.007 13.972  -1.617  1.00 46.29  ? 594 HOH A O   1 
HETATM 9732  O  O   . HOH L 4 .   ? -16.903 42.857  -25.991 1.00 35.73  ? 595 HOH A O   1 
HETATM 9733  O  O   . HOH L 4 .   ? 2.174   45.375  -31.339 1.00 24.91  ? 596 HOH A O   1 
HETATM 9734  O  O   . HOH L 4 .   ? -23.004 38.681  -12.667 1.00 36.25  ? 597 HOH A O   1 
HETATM 9735  O  O   . HOH L 4 .   ? -49.072 12.801  -1.594  1.00 33.65  ? 598 HOH A O   1 
HETATM 9736  O  O   . HOH L 4 .   ? -39.154 20.978  -27.308 1.00 40.03  ? 599 HOH A O   1 
HETATM 9737  O  O   . HOH L 4 .   ? -14.170 23.632  -34.237 1.00 40.81  ? 600 HOH A O   1 
HETATM 9738  O  O   . HOH L 4 .   ? -18.731 11.496  5.584   1.00 42.92  ? 601 HOH A O   1 
HETATM 9739  O  O   . HOH L 4 .   ? 3.768   30.665  -33.369 1.00 36.48  ? 602 HOH A O   1 
HETATM 9740  O  O   . HOH L 4 .   ? -1.907  47.550  -33.773 1.00 33.72  ? 603 HOH A O   1 
HETATM 9741  O  O   . HOH L 4 .   ? -22.955 8.499   3.356   1.00 43.70  ? 604 HOH A O   1 
HETATM 9742  O  O   . HOH M 4 .   ? -31.144 22.339  -50.873 1.00 40.51  ? 501 HOH B O   1 
HETATM 9743  O  O   . HOH M 4 .   ? -29.008 -9.117  -27.396 1.00 37.10  ? 502 HOH B O   1 
HETATM 9744  O  O   . HOH M 4 .   ? -19.256 13.298  -17.622 1.00 30.44  ? 503 HOH B O   1 
HETATM 9745  O  O   . HOH M 4 .   ? -12.497 9.982   -36.199 1.00 33.50  ? 504 HOH B O   1 
HETATM 9746  O  O   . HOH M 4 .   ? 1.276   -8.473  -23.781 1.00 31.86  ? 505 HOH B O   1 
HETATM 9747  O  O   . HOH M 4 .   ? -28.002 -2.069  -30.643 1.00 25.00  ? 506 HOH B O   1 
HETATM 9748  O  O   . HOH M 4 .   ? -28.732 -5.664  -42.513 1.00 40.56  ? 507 HOH B O   1 
HETATM 9749  O  O   . HOH M 4 .   ? -18.425 -7.968  -34.173 1.00 43.42  ? 508 HOH B O   1 
HETATM 9750  O  O   . HOH M 4 .   ? -17.721 15.427  -47.401 1.00 36.57  ? 509 HOH B O   1 
HETATM 9751  O  O   . HOH M 4 .   ? 0.258   -6.309  -21.917 1.00 36.48  ? 510 HOH B O   1 
HETATM 9752  O  O   . HOH M 4 .   ? -27.394 13.125  -32.829 1.00 18.62  ? 511 HOH B O   1 
HETATM 9753  O  O   . HOH M 4 .   ? -22.101 14.665  -52.362 1.00 34.61  ? 512 HOH B O   1 
HETATM 9754  O  O   . HOH M 4 .   ? -18.822 -11.953 -3.999  1.00 35.28  ? 513 HOH B O   1 
HETATM 9755  O  O   . HOH M 4 .   ? -3.223  19.637  -28.348 1.00 35.51  ? 514 HOH B O   1 
HETATM 9756  O  O   . HOH M 4 .   ? -21.363 -5.776  -22.173 1.00 29.38  ? 515 HOH B O   1 
HETATM 9757  O  O   . HOH M 4 .   ? -17.016 19.139  -32.874 1.00 17.29  ? 516 HOH B O   1 
HETATM 9758  O  O   . HOH M 4 .   ? -25.748 4.539   -45.356 1.00 28.57  ? 517 HOH B O   1 
HETATM 9759  O  O   . HOH M 4 .   ? 0.972   -14.893 -13.488 1.00 20.22  ? 518 HOH B O   1 
HETATM 9760  O  O   . HOH M 4 .   ? -3.563  -13.879 -6.414  1.00 28.09  ? 519 HOH B O   1 
HETATM 9761  O  O   . HOH M 4 .   ? -32.667 16.708  -22.487 1.00 35.21  ? 520 HOH B O   1 
HETATM 9762  O  O   . HOH M 4 .   ? -15.012 7.007   -27.344 1.00 25.35  ? 521 HOH B O   1 
HETATM 9763  O  O   . HOH M 4 .   ? 3.640   -5.069  -11.070 1.00 22.54  ? 522 HOH B O   1 
HETATM 9764  O  O   . HOH M 4 .   ? -12.867 4.752   -0.696  1.00 37.31  ? 523 HOH B O   1 
HETATM 9765  O  O   . HOH M 4 .   ? -2.280  -6.049  -7.122  1.00 31.70  ? 524 HOH B O   1 
HETATM 9766  O  O   . HOH M 4 .   ? -36.052 2.560   -38.842 1.00 24.13  ? 525 HOH B O   1 
HETATM 9767  O  O   . HOH M 4 .   ? -14.925 9.164   -21.773 1.00 24.74  ? 526 HOH B O   1 
HETATM 9768  O  O   . HOH M 4 .   ? -12.621 -3.735  -0.762  1.00 34.28  ? 527 HOH B O   1 
HETATM 9769  O  O   . HOH M 4 .   ? -20.361 20.567  -38.506 1.00 25.78  ? 528 HOH B O   1 
HETATM 9770  O  O   . HOH M 4 .   ? -38.824 18.420  -41.512 1.00 42.93  ? 529 HOH B O   1 
HETATM 9771  O  O   . HOH M 4 .   ? -13.138 17.644  -40.109 1.00 33.15  ? 530 HOH B O   1 
HETATM 9772  O  O   . HOH M 4 .   ? -23.971 1.384   -22.786 1.00 25.64  ? 531 HOH B O   1 
HETATM 9773  O  O   . HOH M 4 .   ? -3.502  0.118   -22.398 1.00 24.68  ? 532 HOH B O   1 
HETATM 9774  O  O   . HOH M 4 .   ? -13.440 -13.199 -24.036 1.00 27.65  ? 533 HOH B O   1 
HETATM 9775  O  O   . HOH M 4 .   ? -13.848 1.273   -17.563 1.00 16.52  ? 534 HOH B O   1 
HETATM 9776  O  O   . HOH M 4 .   ? -19.355 18.354  -49.193 1.00 33.82  ? 535 HOH B O   1 
HETATM 9777  O  O   . HOH M 4 .   ? -8.428  -18.571 -18.953 1.00 25.08  ? 536 HOH B O   1 
HETATM 9778  O  O   . HOH M 4 .   ? 1.771   -10.698 -21.630 1.00 30.89  ? 537 HOH B O   1 
HETATM 9779  O  O   . HOH M 4 .   ? -17.319 20.820  -40.343 1.00 27.90  ? 538 HOH B O   1 
HETATM 9780  O  O   . HOH M 4 .   ? -8.582  0.791   -26.302 1.00 23.86  ? 539 HOH B O   1 
HETATM 9781  O  O   . HOH M 4 .   ? 3.565   -2.856  -20.829 1.00 36.65  ? 540 HOH B O   1 
HETATM 9782  O  O   . HOH M 4 .   ? -18.894 -3.268  -3.204  1.00 38.31  ? 541 HOH B O   1 
HETATM 9783  O  O   . HOH M 4 .   ? 2.198   -12.970 -12.963 1.00 26.45  ? 542 HOH B O   1 
HETATM 9784  O  O   . HOH M 4 .   ? -31.796 21.239  -37.846 1.00 28.43  ? 543 HOH B O   1 
HETATM 9785  O  O   . HOH M 4 .   ? -12.625 7.569   -4.837  1.00 36.40  ? 544 HOH B O   1 
HETATM 9786  O  O   . HOH M 4 .   ? -3.457  -0.708  -0.085  1.00 39.83  ? 545 HOH B O   1 
HETATM 9787  O  O   . HOH M 4 .   ? -37.703 14.807  -33.632 1.00 24.84  ? 546 HOH B O   1 
HETATM 9788  O  O   . HOH M 4 .   ? -12.907 -2.303  -24.855 1.00 23.29  ? 547 HOH B O   1 
HETATM 9789  O  O   . HOH M 4 .   ? -29.540 7.813   -52.824 1.00 33.01  ? 548 HOH B O   1 
HETATM 9790  O  O   . HOH M 4 .   ? 0.988   -9.284  -16.636 1.00 25.28  ? 549 HOH B O   1 
HETATM 9791  O  O   . HOH M 4 .   ? -4.350  10.964  -31.973 1.00 45.00  ? 550 HOH B O   1 
HETATM 9792  O  O   . HOH M 4 .   ? -21.642 3.106   -39.787 1.00 25.69  ? 551 HOH B O   1 
HETATM 9793  O  O   . HOH M 4 .   ? -12.822 -8.043  -21.495 1.00 27.31  ? 552 HOH B O   1 
HETATM 9794  O  O   . HOH M 4 .   ? -19.038 -5.779  -10.908 1.00 30.63  ? 553 HOH B O   1 
HETATM 9795  O  O   . HOH M 4 .   ? -25.809 23.641  -42.580 1.00 32.40  ? 554 HOH B O   1 
HETATM 9796  O  O   . HOH M 4 .   ? -10.374 -10.641 -26.980 1.00 23.44  ? 555 HOH B O   1 
HETATM 9797  O  O   . HOH M 4 .   ? -11.778 9.575   -21.656 1.00 27.60  ? 556 HOH B O   1 
HETATM 9798  O  O   . HOH M 4 .   ? -1.645  -16.312 -17.514 1.00 21.26  ? 557 HOH B O   1 
HETATM 9799  O  O   . HOH M 4 .   ? -20.081 0.897   -15.542 1.00 32.55  ? 558 HOH B O   1 
HETATM 9800  O  O   . HOH M 4 .   ? 3.421   3.647   -21.540 1.00 29.55  ? 559 HOH B O   1 
HETATM 9801  O  O   . HOH M 4 .   ? -39.139 17.989  -50.112 1.00 36.88  ? 560 HOH B O   1 
HETATM 9802  O  O   . HOH M 4 .   ? -6.715  12.678  -8.405  1.00 31.01  ? 561 HOH B O   1 
HETATM 9803  O  O   . HOH M 4 .   ? -15.325 6.535   -11.889 1.00 29.29  ? 562 HOH B O   1 
HETATM 9804  O  O   . HOH M 4 .   ? -34.468 -5.986  -22.447 1.00 31.71  ? 563 HOH B O   1 
HETATM 9805  O  O   . HOH M 4 .   ? -30.522 -8.240  -36.875 1.00 35.37  ? 564 HOH B O   1 
HETATM 9806  O  O   . HOH M 4 .   ? -15.341 8.045   -45.666 1.00 32.38  ? 565 HOH B O   1 
HETATM 9807  O  O   . HOH M 4 .   ? -42.198 -6.114  -50.746 1.00 43.57  ? 566 HOH B O   1 
HETATM 9808  O  O   . HOH M 4 .   ? -20.944 11.366  -20.412 1.00 27.74  ? 567 HOH B O   1 
HETATM 9809  O  O   . HOH M 4 .   ? -5.491  5.681   -2.220  1.00 30.54  ? 568 HOH B O   1 
HETATM 9810  O  O   . HOH M 4 .   ? -48.419 16.719  -41.291 1.00 42.68  ? 569 HOH B O   1 
HETATM 9811  O  O   . HOH M 4 .   ? 1.945   -5.836  -7.755  1.00 42.49  ? 570 HOH B O   1 
HETATM 9812  O  O   . HOH M 4 .   ? 3.390   -12.522 -4.590  1.00 35.16  ? 571 HOH B O   1 
HETATM 9813  O  O   . HOH M 4 .   ? 1.893   -6.823  -18.151 1.00 26.84  ? 572 HOH B O   1 
HETATM 9814  O  O   . HOH M 4 .   ? -21.406 4.308   -8.158  1.00 13.58  ? 573 HOH B O   1 
HETATM 9815  O  O   . HOH M 4 .   ? -24.783 -7.855  -35.012 1.00 31.52  ? 574 HOH B O   1 
HETATM 9816  O  O   . HOH M 4 .   ? -40.439 14.718  -33.192 1.00 33.02  ? 575 HOH B O   1 
HETATM 9817  O  O   . HOH M 4 .   ? -19.268 12.273  -14.595 1.00 33.05  ? 576 HOH B O   1 
HETATM 9818  O  O   . HOH M 4 .   ? 0.719   -2.890  -5.321  1.00 37.93  ? 577 HOH B O   1 
HETATM 9819  O  O   . HOH M 4 .   ? -3.056  -18.719 -17.230 1.00 26.46  ? 578 HOH B O   1 
HETATM 9820  O  O   . HOH M 4 .   ? -20.885 -8.771  -10.933 1.00 33.93  ? 579 HOH B O   1 
HETATM 9821  O  O   . HOH M 4 .   ? -33.614 -3.978  -43.263 1.00 29.55  ? 580 HOH B O   1 
HETATM 9822  O  O   . HOH M 4 .   ? -43.662 -6.342  -53.184 1.00 47.91  ? 581 HOH B O   1 
HETATM 9823  O  O   . HOH M 4 .   ? -10.125 4.443   0.120   1.00 35.82  ? 582 HOH B O   1 
HETATM 9824  O  O   . HOH M 4 .   ? -27.857 -10.642 -27.945 1.00 42.00  ? 583 HOH B O   1 
HETATM 9825  O  O   . HOH M 4 .   ? 0.186   -3.848  -7.739  1.00 28.00  ? 584 HOH B O   1 
HETATM 9826  O  O   . HOH M 4 .   ? -20.049 -8.206  -33.158 1.00 56.47  ? 585 HOH B O   1 
HETATM 9827  O  O   . HOH M 4 .   ? -11.454 6.381   -31.022 1.00 32.95  ? 586 HOH B O   1 
HETATM 9828  O  O   . HOH M 4 .   ? -22.962 -10.766 -10.127 1.00 34.09  ? 587 HOH B O   1 
HETATM 9829  O  O   . HOH M 4 .   ? -19.594 -7.191  -9.523  1.00 32.46  ? 588 HOH B O   1 
HETATM 9830  O  O   . HOH M 4 .   ? 1.129   -16.307 -15.851 1.00 28.51  ? 589 HOH B O   1 
HETATM 9831  O  O   . HOH M 4 .   ? -27.889 -8.034  -40.688 1.00 35.08  ? 590 HOH B O   1 
HETATM 9832  O  O   . HOH M 4 .   ? 1.977   -8.278  -20.192 1.00 30.85  ? 591 HOH B O   1 
HETATM 9833  O  O   . HOH M 4 .   ? -10.575 5.046   -32.530 1.00 39.57  ? 592 HOH B O   1 
HETATM 9834  O  O   . HOH M 4 .   ? 2.751   -15.341 -16.903 1.00 49.55  ? 593 HOH B O   1 
HETATM 9835  O  O   . HOH N 4 .   ? -31.795 65.374  -67.014 1.00 49.89  ? 501 HOH D O   1 
HETATM 9836  O  O   . HOH N 4 .   ? -1.548  73.449  -73.403 1.00 43.03  ? 502 HOH D O   1 
HETATM 9837  O  O   . HOH N 4 .   ? -41.864 31.377  -48.166 1.00 40.62  ? 503 HOH D O   1 
HETATM 9838  O  O   . HOH N 4 .   ? -18.778 67.657  -57.903 1.00 25.18  ? 504 HOH D O   1 
HETATM 9839  O  O   . HOH N 4 .   ? -23.807 30.911  -38.809 1.00 34.59  ? 505 HOH D O   1 
HETATM 9840  O  O   . HOH N 4 .   ? -3.156  71.589  -75.186 1.00 29.97  ? 506 HOH D O   1 
HETATM 9841  O  O   . HOH N 4 .   ? -28.387 63.216  -62.665 1.00 38.49  ? 507 HOH D O   1 
HETATM 9842  O  O   . HOH N 4 .   ? -16.130 46.431  -45.487 1.00 40.92  ? 508 HOH D O   1 
HETATM 9843  O  O   . HOH N 4 .   ? 9.568   64.429  -51.773 1.00 58.57  ? 509 HOH D O   1 
HETATM 9844  O  O   . HOH N 4 .   ? -15.782 79.464  -70.175 1.00 36.77  ? 510 HOH D O   1 
HETATM 9845  O  O   . HOH N 4 .   ? -14.126 80.054  -74.149 1.00 32.47  ? 511 HOH D O   1 
HETATM 9846  O  O   . HOH N 4 .   ? -35.229 34.944  -58.826 1.00 31.48  ? 512 HOH D O   1 
HETATM 9847  O  O   . HOH N 4 .   ? -39.124 31.925  -53.347 1.00 33.11  ? 513 HOH D O   1 
HETATM 9848  O  O   . HOH N 4 .   ? -5.003  67.370  -56.365 1.00 26.41  ? 514 HOH D O   1 
HETATM 9849  O  O   . HOH N 4 .   ? -25.782 50.234  -56.525 1.00 29.30  ? 515 HOH D O   1 
HETATM 9850  O  O   . HOH N 4 .   ? -19.483 53.028  -44.356 1.00 21.46  ? 516 HOH D O   1 
HETATM 9851  O  O   . HOH N 4 .   ? -13.927 58.985  -65.780 1.00 27.10  ? 517 HOH D O   1 
HETATM 9852  O  O   . HOH N 4 .   ? -8.478  68.651  -47.996 1.00 32.12  ? 518 HOH D O   1 
HETATM 9853  O  O   . HOH N 4 .   ? -27.704 70.944  -65.610 1.00 37.60  ? 519 HOH D O   1 
HETATM 9854  O  O   . HOH N 4 .   ? -24.207 57.312  -70.928 1.00 25.50  ? 520 HOH D O   1 
HETATM 9855  O  O   . HOH N 4 .   ? -1.281  65.929  -75.000 1.00 37.60  ? 521 HOH D O   1 
HETATM 9856  O  O   . HOH N 4 .   ? -39.626 52.814  -36.663 1.00 35.00  ? 522 HOH D O   1 
HETATM 9857  O  O   . HOH N 4 .   ? -17.089 52.050  -51.536 1.00 19.21  ? 523 HOH D O   1 
HETATM 9858  O  O   . HOH N 4 .   ? -8.479  73.904  -79.466 1.00 40.56  ? 524 HOH D O   1 
HETATM 9859  O  O   . HOH N 4 .   ? -12.577 60.875  -50.259 1.00 21.87  ? 525 HOH D O   1 
HETATM 9860  O  O   . HOH N 4 .   ? -21.506 64.867  -44.457 1.00 37.04  ? 526 HOH D O   1 
HETATM 9861  O  O   . HOH N 4 .   ? -27.081 46.967  -50.222 1.00 15.42  ? 527 HOH D O   1 
HETATM 9862  O  O   . HOH N 4 .   ? -41.845 38.603  -39.487 1.00 24.24  ? 528 HOH D O   1 
HETATM 9863  O  O   . HOH N 4 .   ? -17.283 73.995  -67.497 1.00 29.09  ? 529 HOH D O   1 
HETATM 9864  O  O   . HOH N 4 .   ? -21.041 27.963  -48.086 1.00 30.53  ? 530 HOH D O   1 
HETATM 9865  O  O   . HOH N 4 .   ? 1.842   55.204  -56.981 1.00 31.02  ? 531 HOH D O   1 
HETATM 9866  O  O   . HOH N 4 .   ? -4.873  64.153  -43.870 1.00 43.44  ? 532 HOH D O   1 
HETATM 9867  O  O   . HOH N 4 .   ? -9.313  61.658  -74.585 1.00 28.23  ? 533 HOH D O   1 
HETATM 9868  O  O   . HOH N 4 .   ? 0.832   80.304  -72.188 1.00 32.04  ? 534 HOH D O   1 
HETATM 9869  O  O   . HOH N 4 .   ? -3.674  59.504  -67.179 1.00 37.69  ? 535 HOH D O   1 
HETATM 9870  O  O   . HOH N 4 .   ? -44.416 51.041  -46.618 1.00 29.56  ? 536 HOH D O   1 
HETATM 9871  O  O   . HOH N 4 .   ? -12.815 52.040  -45.367 1.00 28.46  ? 537 HOH D O   1 
HETATM 9872  O  O   . HOH N 4 .   ? -1.986  78.177  -74.883 1.00 33.89  ? 538 HOH D O   1 
HETATM 9873  O  O   . HOH N 4 .   ? -41.432 38.906  -32.430 1.00 29.86  ? 539 HOH D O   1 
HETATM 9874  O  O   . HOH N 4 .   ? -20.093 67.719  -46.923 1.00 30.14  ? 540 HOH D O   1 
HETATM 9875  O  O   . HOH N 4 .   ? -27.892 54.981  -48.094 1.00 20.07  ? 541 HOH D O   1 
HETATM 9876  O  O   . HOH N 4 .   ? -30.426 58.886  -60.319 1.00 41.32  ? 542 HOH D O   1 
HETATM 9877  O  O   . HOH N 4 .   ? -19.114 42.494  -34.171 1.00 28.96  ? 543 HOH D O   1 
HETATM 9878  O  O   . HOH N 4 .   ? -18.811 71.653  -52.461 1.00 31.64  ? 544 HOH D O   1 
HETATM 9879  O  O   . HOH N 4 .   ? -21.998 42.479  -41.574 1.00 31.05  ? 545 HOH D O   1 
HETATM 9880  O  O   . HOH N 4 .   ? -37.707 51.884  -50.223 1.00 27.09  ? 546 HOH D O   1 
HETATM 9881  O  O   . HOH N 4 .   ? -0.142  81.374  -63.504 1.00 32.68  ? 547 HOH D O   1 
HETATM 9882  O  O   . HOH N 4 .   ? -26.317 48.666  -58.523 1.00 23.69  ? 548 HOH D O   1 
HETATM 9883  O  O   . HOH N 4 .   ? -4.676  74.259  -50.235 1.00 37.28  ? 549 HOH D O   1 
HETATM 9884  O  O   . HOH N 4 .   ? -12.650 78.087  -51.862 1.00 32.76  ? 550 HOH D O   1 
HETATM 9885  O  O   . HOH N 4 .   ? -5.258  82.344  -66.356 1.00 26.18  ? 551 HOH D O   1 
HETATM 9886  O  O   . HOH N 4 .   ? -35.377 57.740  -34.904 1.00 41.28  ? 552 HOH D O   1 
HETATM 9887  O  O   . HOH N 4 .   ? -27.910 37.774  -57.547 1.00 35.39  ? 553 HOH D O   1 
HETATM 9888  O  O   . HOH N 4 .   ? -29.125 48.849  -59.044 1.00 29.14  ? 554 HOH D O   1 
HETATM 9889  O  O   . HOH N 4 .   ? -39.102 38.922  -41.221 1.00 38.91  ? 555 HOH D O   1 
HETATM 9890  O  O   . HOH N 4 .   ? -28.780 31.619  -40.894 1.00 35.65  ? 556 HOH D O   1 
HETATM 9891  O  O   . HOH N 4 .   ? -39.275 51.305  -33.250 1.00 24.76  ? 557 HOH D O   1 
HETATM 9892  O  O   . HOH N 4 .   ? -7.342  59.837  -74.883 1.00 46.96  ? 558 HOH D O   1 
HETATM 9893  O  O   . HOH N 4 .   ? -25.655 70.975  -68.552 1.00 30.86  ? 559 HOH D O   1 
HETATM 9894  O  O   . HOH N 4 .   ? -6.014  68.972  -49.527 1.00 30.59  ? 560 HOH D O   1 
HETATM 9895  O  O   . HOH N 4 .   ? -28.721 29.710  -49.441 1.00 39.37  ? 561 HOH D O   1 
HETATM 9896  O  O   . HOH N 4 .   ? -41.994 48.767  -39.511 1.00 22.95  ? 562 HOH D O   1 
HETATM 9897  O  O   . HOH N 4 .   ? -9.367  61.402  -81.794 1.00 30.39  ? 563 HOH D O   1 
HETATM 9898  O  O   . HOH N 4 .   ? -23.816 40.985  -58.581 1.00 31.63  ? 564 HOH D O   1 
HETATM 9899  O  O   . HOH N 4 .   ? -19.661 37.216  -50.554 1.00 21.93  ? 565 HOH D O   1 
HETATM 9900  O  O   . HOH N 4 .   ? -4.123  68.044  -82.941 1.00 36.19  ? 566 HOH D O   1 
HETATM 9901  O  O   . HOH N 4 .   ? -6.650  80.807  -59.358 1.00 27.38  ? 567 HOH D O   1 
HETATM 9902  O  O   . HOH N 4 .   ? -27.476 58.131  -42.295 1.00 34.51  ? 568 HOH D O   1 
HETATM 9903  O  O   . HOH N 4 .   ? -22.626 35.634  -35.057 1.00 31.00  ? 569 HOH D O   1 
HETATM 9904  O  O   . HOH N 4 .   ? 5.598   82.179  -50.853 1.00 46.94  ? 570 HOH D O   1 
HETATM 9905  O  O   . HOH N 4 .   ? -2.624  82.163  -73.540 1.00 40.77  ? 571 HOH D O   1 
HETATM 9906  O  O   . HOH N 4 .   ? -19.563 40.733  -53.585 1.00 41.78  ? 572 HOH D O   1 
HETATM 9907  O  O   . HOH N 4 .   ? -22.743 39.258  -38.121 1.00 35.54  ? 573 HOH D O   1 
HETATM 9908  O  O   . HOH N 4 .   ? -23.517 38.762  -55.882 1.00 41.58  ? 574 HOH D O   1 
HETATM 9909  O  O   . HOH N 4 .   ? -13.720 82.147  -75.481 1.00 43.97  ? 575 HOH D O   1 
HETATM 9910  O  O   . HOH N 4 .   ? -12.409 61.061  -75.735 1.00 35.18  ? 576 HOH D O   1 
HETATM 9911  O  O   . HOH N 4 .   ? -30.242 28.881  -48.390 1.00 35.43  ? 577 HOH D O   1 
HETATM 9912  O  O   . HOH N 4 .   ? -19.260 46.262  -45.468 1.00 30.43  ? 578 HOH D O   1 
HETATM 9913  O  O   . HOH N 4 .   ? -16.673 76.487  -79.623 1.00 38.72  ? 579 HOH D O   1 
HETATM 9914  O  O   . HOH N 4 .   ? -28.652 61.764  -59.966 1.00 42.84  ? 580 HOH D O   1 
HETATM 9915  O  O   . HOH N 4 .   ? -28.960 56.661  -46.075 1.00 30.12  ? 581 HOH D O   1 
HETATM 9916  O  O   . HOH N 4 .   ? -26.876 55.740  -44.641 1.00 29.65  ? 582 HOH D O   1 
HETATM 9917  O  O   . HOH N 4 .   ? -46.192 38.781  -36.610 1.00 38.64  ? 583 HOH D O   1 
HETATM 9918  O  O   . HOH N 4 .   ? -13.478 63.290  -76.598 1.00 25.80  ? 584 HOH D O   1 
HETATM 9919  O  O   . HOH N 4 .   ? -27.036 57.205  -69.637 1.00 40.45  ? 585 HOH D O   1 
HETATM 9920  O  O   . HOH N 4 .   ? -26.919 25.312  -47.034 1.00 26.12  ? 586 HOH D O   1 
HETATM 9921  O  O   . HOH N 4 .   ? -42.195 49.662  -32.871 1.00 36.06  ? 587 HOH D O   1 
HETATM 9922  O  O   . HOH N 4 .   ? -42.571 51.278  -38.009 1.00 32.94  ? 588 HOH D O   1 
HETATM 9923  O  O   . HOH N 4 .   ? -43.063 50.762  -34.096 1.00 32.64  ? 589 HOH D O   1 
HETATM 9924  O  O   . HOH O 4 .   ? -8.909  22.517  -70.007 1.00 47.60  ? 501 HOH C O   1 
HETATM 9925  O  O   . HOH O 4 .   ? -12.588 42.275  -68.550 1.00 38.40  ? 502 HOH C O   1 
HETATM 9926  O  O   . HOH O 4 .   ? -4.046  54.067  -81.534 1.00 42.25  ? 503 HOH C O   1 
HETATM 9927  O  O   . HOH O 4 .   ? -26.589 38.418  -92.197 1.00 30.88  ? 504 HOH C O   1 
HETATM 9928  O  O   . HOH O 4 .   ? -13.215 28.848  -38.742 1.00 46.12  ? 505 HOH C O   1 
HETATM 9929  O  O   . HOH O 4 .   ? -42.078 54.273  -82.607 1.00 39.84  ? 506 HOH C O   1 
HETATM 9930  O  O   . HOH O 4 .   ? -39.657 50.920  -81.649 1.00 27.76  ? 507 HOH C O   1 
HETATM 9931  O  O   . HOH O 4 .   ? -21.673 54.048  -81.305 1.00 30.32  ? 508 HOH C O   1 
HETATM 9932  O  O   . HOH O 4 .   ? 3.264   19.795  -57.534 1.00 38.10  ? 509 HOH C O   1 
HETATM 9933  O  O   . HOH O 4 .   ? -2.990  22.520  -50.049 1.00 42.74  ? 510 HOH C O   1 
HETATM 9934  O  O   . HOH O 4 .   ? -0.063  28.441  -51.211 1.00 36.58  ? 511 HOH C O   1 
HETATM 9935  O  O   . HOH O 4 .   ? -11.420 42.698  -74.733 1.00 41.77  ? 512 HOH C O   1 
HETATM 9936  O  O   . HOH O 4 .   ? -22.107 36.493  -81.621 1.00 25.64  ? 513 HOH C O   1 
HETATM 9937  O  O   . HOH O 4 .   ? -34.514 55.135  -91.700 1.00 26.55  ? 514 HOH C O   1 
HETATM 9938  O  O   . HOH O 4 .   ? -17.994 52.289  -75.344 1.00 22.35  ? 515 HOH C O   1 
HETATM 9939  O  O   . HOH O 4 .   ? -32.157 44.960  -65.632 1.00 29.81  ? 516 HOH C O   1 
HETATM 9940  O  O   . HOH O 4 .   ? -39.947 52.195  -87.960 1.00 20.92  ? 517 HOH C O   1 
HETATM 9941  O  O   . HOH O 4 .   ? -27.783 46.166  -74.727 1.00 24.14  ? 518 HOH C O   1 
HETATM 9942  O  O   . HOH O 4 .   ? -14.617 40.145  -70.371 1.00 28.68  ? 519 HOH C O   1 
HETATM 9943  O  O   . HOH O 4 .   ? -23.627 22.245  -70.393 1.00 36.26  ? 520 HOH C O   1 
HETATM 9944  O  O   . HOH O 4 .   ? -8.158  52.265  -84.148 1.00 44.22  ? 521 HOH C O   1 
HETATM 9945  O  O   . HOH O 4 .   ? -28.338 30.387  -72.860 1.00 40.60  ? 522 HOH C O   1 
HETATM 9946  O  O   . HOH O 4 .   ? -35.239 55.587  -98.412 1.00 35.69  ? 523 HOH C O   1 
HETATM 9947  O  O   . HOH O 4 .   ? -22.010 51.997  -91.215 1.00 27.08  ? 524 HOH C O   1 
HETATM 9948  O  O   . HOH O 4 .   ? -14.026 26.279  -67.376 1.00 44.15  ? 525 HOH C O   1 
HETATM 9949  O  O   . HOH O 4 .   ? -20.366 38.792  -56.278 1.00 41.51  ? 526 HOH C O   1 
HETATM 9950  O  O   . HOH O 4 .   ? 0.421   18.071  -61.660 1.00 33.12  ? 527 HOH C O   1 
HETATM 9951  O  O   . HOH O 4 .   ? -2.994  33.612  -70.104 1.00 34.10  ? 528 HOH C O   1 
HETATM 9952  O  O   . HOH O 4 .   ? -4.060  54.017  -71.724 1.00 37.96  ? 529 HOH C O   1 
HETATM 9953  O  O   . HOH O 4 .   ? -17.215 43.104  -48.480 1.00 39.33  ? 530 HOH C O   1 
HETATM 9954  O  O   . HOH O 4 .   ? -18.204 49.109  -88.403 1.00 28.14  ? 531 HOH C O   1 
HETATM 9955  O  O   . HOH O 4 .   ? -43.500 22.251  -71.234 1.00 38.36  ? 532 HOH C O   1 
HETATM 9956  O  O   . HOH O 4 .   ? -15.008 39.819  -65.365 1.00 25.23  ? 533 HOH C O   1 
HETATM 9957  O  O   . HOH O 4 .   ? -13.130 42.325  -79.557 1.00 41.43  ? 534 HOH C O   1 
HETATM 9958  O  O   . HOH O 4 .   ? -12.928 34.694  -60.828 1.00 21.98  ? 535 HOH C O   1 
HETATM 9959  O  O   . HOH O 4 .   ? -13.986 42.562  -64.822 1.00 26.72  ? 536 HOH C O   1 
HETATM 9960  O  O   . HOH O 4 .   ? -36.566 35.011  -80.101 1.00 24.26  ? 537 HOH C O   1 
HETATM 9961  O  O   . HOH O 4 .   ? -23.151 34.777  -65.094 1.00 29.86  ? 538 HOH C O   1 
HETATM 9962  O  O   . HOH O 4 .   ? -48.666 35.278  -81.603 1.00 54.68  ? 539 HOH C O   1 
HETATM 9963  O  O   . HOH O 4 .   ? -4.252  50.816  -73.616 1.00 34.78  ? 540 HOH C O   1 
HETATM 9964  O  O   . HOH O 4 .   ? -38.233 47.056  -74.328 1.00 27.31  ? 541 HOH C O   1 
HETATM 9965  O  O   . HOH O 4 .   ? -30.000 50.568  -96.462 1.00 40.52  ? 542 HOH C O   1 
HETATM 9966  O  O   . HOH O 4 .   ? -42.097 50.481  -90.159 1.00 27.63  ? 543 HOH C O   1 
HETATM 9967  O  O   . HOH O 4 .   ? -10.576 41.380  -48.527 1.00 36.11  ? 544 HOH C O   1 
HETATM 9968  O  O   . HOH O 4 .   ? -26.957 56.088  -94.473 1.00 26.34  ? 545 HOH C O   1 
HETATM 9969  O  O   . HOH O 4 .   ? -17.484 38.978  -76.892 1.00 25.15  ? 546 HOH C O   1 
HETATM 9970  O  O   . HOH O 4 .   ? -12.550 37.894  -70.794 1.00 38.03  ? 547 HOH C O   1 
HETATM 9971  O  O   . HOH O 4 .   ? -12.269 20.515  -67.566 1.00 37.43  ? 548 HOH C O   1 
HETATM 9972  O  O   . HOH O 4 .   ? 6.167   31.833  -60.751 1.00 39.09  ? 549 HOH C O   1 
HETATM 9973  O  O   . HOH O 4 .   ? -44.501 47.097  -95.695 1.00 27.51  ? 550 HOH C O   1 
HETATM 9974  O  O   . HOH O 4 .   ? -20.289 44.399  -63.027 1.00 27.58  ? 551 HOH C O   1 
HETATM 9975  O  O   . HOH O 4 .   ? -11.969 31.217  -68.216 1.00 23.83  ? 552 HOH C O   1 
HETATM 9976  O  O   . HOH O 4 .   ? 1.485   43.447  -56.672 1.00 33.01  ? 553 HOH C O   1 
HETATM 9977  O  O   . HOH O 4 .   ? -16.668 46.392  -88.241 1.00 27.76  ? 554 HOH C O   1 
HETATM 9978  O  O   . HOH O 4 .   ? -11.406 25.524  -65.151 1.00 28.01  ? 555 HOH C O   1 
HETATM 9979  O  O   . HOH O 4 .   ? -12.266 33.187  -37.265 1.00 38.03  ? 556 HOH C O   1 
HETATM 9980  O  O   . HOH O 4 .   ? -40.817 52.130  -92.202 1.00 21.77  ? 557 HOH C O   1 
HETATM 9981  O  O   . HOH O 4 .   ? 2.915   25.045  -61.111 1.00 34.43  ? 558 HOH C O   1 
HETATM 9982  O  O   . HOH O 4 .   ? -22.083 46.439  -93.602 1.00 33.11  ? 559 HOH C O   1 
HETATM 9983  O  O   . HOH O 4 .   ? -20.643 58.348  -89.088 1.00 36.35  ? 560 HOH C O   1 
HETATM 9984  O  O   . HOH O 4 .   ? -44.966 52.183  -90.017 1.00 30.31  ? 561 HOH C O   1 
HETATM 9985  O  O   . HOH O 4 .   ? -11.807 42.752  -64.681 1.00 25.79  ? 562 HOH C O   1 
HETATM 9986  O  O   . HOH O 4 .   ? -13.943 36.359  -72.119 1.00 29.72  ? 563 HOH C O   1 
HETATM 9987  O  O   . HOH O 4 .   ? -3.951  38.754  -45.712 1.00 32.96  ? 564 HOH C O   1 
HETATM 9988  O  O   . HOH O 4 .   ? -16.458 33.203  -82.703 1.00 25.29  ? 565 HOH C O   1 
HETATM 9989  O  O   . HOH O 4 .   ? -50.091 40.680  -87.956 1.00 30.43  ? 566 HOH C O   1 
HETATM 9990  O  O   . HOH O 4 .   ? -36.956 34.824  -93.482 1.00 27.21  ? 567 HOH C O   1 
HETATM 9991  O  O   . HOH O 4 .   ? -18.605 15.034  -52.780 1.00 38.29  ? 568 HOH C O   1 
HETATM 9992  O  O   . HOH O 4 .   ? 3.764   27.435  -51.695 1.00 42.84  ? 569 HOH C O   1 
HETATM 9993  O  O   . HOH O 4 .   ? -17.189 29.523  -52.119 1.00 25.36  ? 570 HOH C O   1 
HETATM 9994  O  O   . HOH O 4 .   ? -24.321 57.540  -75.054 1.00 29.04  ? 571 HOH C O   1 
HETATM 9995  O  O   . HOH O 4 .   ? -38.794 64.253  -77.950 1.00 47.45  ? 572 HOH C O   1 
HETATM 9996  O  O   . HOH O 4 .   ? 2.214   28.025  -66.199 1.00 39.52  ? 573 HOH C O   1 
HETATM 9997  O  O   . HOH O 4 .   ? -24.368 25.203  -77.272 1.00 25.38  ? 574 HOH C O   1 
HETATM 9998  O  O   . HOH O 4 .   ? -12.755 28.553  -69.029 1.00 28.39  ? 575 HOH C O   1 
HETATM 9999  O  O   . HOH O 4 .   ? -42.629 55.422  -99.306 1.00 25.60  ? 576 HOH C O   1 
HETATM 10000 O  O   . HOH O 4 .   ? -26.224 21.275  -70.731 1.00 35.58  ? 577 HOH C O   1 
HETATM 10001 O  O   . HOH O 4 .   ? -39.041 34.868  -93.980 1.00 50.83  ? 578 HOH C O   1 
HETATM 10002 O  O   . HOH O 4 .   ? -21.831 56.982  -91.640 1.00 39.77  ? 579 HOH C O   1 
# 
