data_8R25
# 
_entry.id   8R25 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R25         pdb_00008r25 10.2210/pdb8r25/pdb 
WWPDB D_1292134461 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R25 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'complexed with another inhibitor' 7QB2 unspecified 
PDB 'complexed with another inhibitor' 7QFM unspecified 
PDB 'complexed with another inhibitor' 7Z6U unspecified 
PDB 'complexed with another inhibitor' 8AFR unspecified 
PDB 'complexed with another inhibitor' 8R0H unspecified 
PDB 'complexed with another inhibitor' 8R0Q unspecified 
PDB 'complexed with another inhibitor' 8R0W unspecified 
PDB 'complexed with another inhibitor' 8R0Y unspecified 
PDB 'complexed with another inhibitor' 8R10 unspecified 
PDB 'complexed with another inhibitor' 8R18 unspecified 
PDB 'complexed with another inhibitor' 8R1K unspecified 
PDB 'complexed with another inhibitor' 8R1N unspecified 
PDB 'complexed with another inhibitor' 8R1P unspecified 
PDB 'complexed with another inhibitor' 8R1T unspecified 
PDB 'complexed with another inhibitor' 8R1W unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wibke.diederich@staff.uni-marburg.de 
_pdbx_contact_author.name_first         Wibke 
_pdbx_contact_author.name_last          Diederich 
_pdbx_contact_author.name_mi            E. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5671-6575 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hochban, P.M.M.' 1 0000-0003-3526-7314 
'Heine, A.'       2 0000-0002-5285-4089 
'Diederich, W.E.' 3 0000-0001-5671-6575 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Pim1 in complex with 4-(5-(4-aminophenyl)-1H-pyrazol-1-yl)benzoic acid and Pimtide' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hochban, P.M.M.' 1 0000-0003-3526-7314 
primary 'Heyder, L.'      2 ?                   
primary 'Heine, A.'       3 0000-0002-5285-4089 
primary 'Diederich, W.E.' 4 0000-0001-5671-6575 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Serine/threonine-protein kinase pim-1'             35670.477 1   2.7.11.1 R250G ? ? 
2 polymer     syn Pimtide                                             1592.850  1   ?        ?     ? ? 
3 non-polymer syn GLYCEROL                                            92.094    1   ?        ?     ? ? 
4 non-polymer syn '4-(5-(4-aminophenyl)-1H-pyrazol-1-yl)benzoic acid' 279.293   1   ?        ?     ? ? 
5 water       nat water                                               18.015    102 ?        ?     ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;SMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGE
LPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
IPFEHDEEIIGGQVFFRQRVS(SEP)ECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
;SMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGE
LPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
IPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
A ? 
2 'polypeptide(L)' no no  ARKRRRHPSGPPTA ARKRRRHPSGPPTA B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 GLYCEROL                                            GOL 
4 '4-(5-(4-aminophenyl)-1H-pyrazol-1-yl)benzoic acid' XJL 
5 water                                               HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   MET n 
1 3   LEU n 
1 4   LEU n 
1 5   SER n 
1 6   LYS n 
1 7   ILE n 
1 8   ASN n 
1 9   SER n 
1 10  LEU n 
1 11  ALA n 
1 12  HIS n 
1 13  LEU n 
1 14  ARG n 
1 15  ALA n 
1 16  ALA n 
1 17  PRO n 
1 18  CYS n 
1 19  ASN n 
1 20  ASP n 
1 21  LEU n 
1 22  HIS n 
1 23  ALA n 
1 24  THR n 
1 25  LYS n 
1 26  LEU n 
1 27  ALA n 
1 28  PRO n 
1 29  GLY n 
1 30  LYS n 
1 31  GLU n 
1 32  LYS n 
1 33  GLU n 
1 34  PRO n 
1 35  LEU n 
1 36  GLU n 
1 37  SER n 
1 38  GLN n 
1 39  TYR n 
1 40  GLN n 
1 41  VAL n 
1 42  GLY n 
1 43  PRO n 
1 44  LEU n 
1 45  LEU n 
1 46  GLY n 
1 47  SER n 
1 48  GLY n 
1 49  GLY n 
1 50  PHE n 
1 51  GLY n 
1 52  SER n 
1 53  VAL n 
1 54  TYR n 
1 55  SER n 
1 56  GLY n 
1 57  ILE n 
1 58  ARG n 
1 59  VAL n 
1 60  SER n 
1 61  ASP n 
1 62  ASN n 
1 63  LEU n 
1 64  PRO n 
1 65  VAL n 
1 66  ALA n 
1 67  ILE n 
1 68  LYS n 
1 69  HIS n 
1 70  VAL n 
1 71  GLU n 
1 72  LYS n 
1 73  ASP n 
1 74  ARG n 
1 75  ILE n 
1 76  SER n 
1 77  ASP n 
1 78  TRP n 
1 79  GLY n 
1 80  GLU n 
1 81  LEU n 
1 82  PRO n 
1 83  ASN n 
1 84  GLY n 
1 85  THR n 
1 86  ARG n 
1 87  VAL n 
1 88  PRO n 
1 89  MET n 
1 90  GLU n 
1 91  VAL n 
1 92  VAL n 
1 93  LEU n 
1 94  LEU n 
1 95  LYS n 
1 96  LYS n 
1 97  VAL n 
1 98  SER n 
1 99  SER n 
1 100 GLY n 
1 101 PHE n 
1 102 SER n 
1 103 GLY n 
1 104 VAL n 
1 105 ILE n 
1 106 ARG n 
1 107 LEU n 
1 108 LEU n 
1 109 ASP n 
1 110 TRP n 
1 111 PHE n 
1 112 GLU n 
1 113 ARG n 
1 114 PRO n 
1 115 ASP n 
1 116 SER n 
1 117 PHE n 
1 118 VAL n 
1 119 LEU n 
1 120 ILE n 
1 121 LEU n 
1 122 GLU n 
1 123 ARG n 
1 124 PRO n 
1 125 GLU n 
1 126 PRO n 
1 127 VAL n 
1 128 GLN n 
1 129 ASP n 
1 130 LEU n 
1 131 PHE n 
1 132 ASP n 
1 133 PHE n 
1 134 ILE n 
1 135 THR n 
1 136 GLU n 
1 137 ARG n 
1 138 GLY n 
1 139 ALA n 
1 140 LEU n 
1 141 GLN n 
1 142 GLU n 
1 143 GLU n 
1 144 LEU n 
1 145 ALA n 
1 146 ARG n 
1 147 SER n 
1 148 PHE n 
1 149 PHE n 
1 150 TRP n 
1 151 GLN n 
1 152 VAL n 
1 153 LEU n 
1 154 GLU n 
1 155 ALA n 
1 156 VAL n 
1 157 ARG n 
1 158 HIS n 
1 159 CYS n 
1 160 HIS n 
1 161 ASN n 
1 162 CYS n 
1 163 GLY n 
1 164 VAL n 
1 165 LEU n 
1 166 HIS n 
1 167 ARG n 
1 168 ASP n 
1 169 ILE n 
1 170 LYS n 
1 171 ASP n 
1 172 GLU n 
1 173 ASN n 
1 174 ILE n 
1 175 LEU n 
1 176 ILE n 
1 177 ASP n 
1 178 LEU n 
1 179 ASN n 
1 180 ARG n 
1 181 GLY n 
1 182 GLU n 
1 183 LEU n 
1 184 LYS n 
1 185 LEU n 
1 186 ILE n 
1 187 ASP n 
1 188 PHE n 
1 189 GLY n 
1 190 SER n 
1 191 GLY n 
1 192 ALA n 
1 193 LEU n 
1 194 LEU n 
1 195 LYS n 
1 196 ASP n 
1 197 THR n 
1 198 VAL n 
1 199 TYR n 
1 200 THR n 
1 201 ASP n 
1 202 PHE n 
1 203 ASP n 
1 204 GLY n 
1 205 THR n 
1 206 ARG n 
1 207 VAL n 
1 208 TYR n 
1 209 SER n 
1 210 PRO n 
1 211 PRO n 
1 212 GLU n 
1 213 TRP n 
1 214 ILE n 
1 215 ARG n 
1 216 TYR n 
1 217 HIS n 
1 218 ARG n 
1 219 TYR n 
1 220 HIS n 
1 221 GLY n 
1 222 ARG n 
1 223 SER n 
1 224 ALA n 
1 225 ALA n 
1 226 VAL n 
1 227 TRP n 
1 228 SER n 
1 229 LEU n 
1 230 GLY n 
1 231 ILE n 
1 232 LEU n 
1 233 LEU n 
1 234 TYR n 
1 235 ASP n 
1 236 MET n 
1 237 VAL n 
1 238 CYS n 
1 239 GLY n 
1 240 ASP n 
1 241 ILE n 
1 242 PRO n 
1 243 PHE n 
1 244 GLU n 
1 245 HIS n 
1 246 ASP n 
1 247 GLU n 
1 248 GLU n 
1 249 ILE n 
1 250 ILE n 
1 251 GLY n 
1 252 GLY n 
1 253 GLN n 
1 254 VAL n 
1 255 PHE n 
1 256 PHE n 
1 257 ARG n 
1 258 GLN n 
1 259 ARG n 
1 260 VAL n 
1 261 SER n 
1 262 SEP n 
1 263 GLU n 
1 264 CYS n 
1 265 GLN n 
1 266 HIS n 
1 267 LEU n 
1 268 ILE n 
1 269 ARG n 
1 270 TRP n 
1 271 CYS n 
1 272 LEU n 
1 273 ALA n 
1 274 LEU n 
1 275 ARG n 
1 276 PRO n 
1 277 SER n 
1 278 ASP n 
1 279 ARG n 
1 280 PRO n 
1 281 THR n 
1 282 PHE n 
1 283 GLU n 
1 284 GLU n 
1 285 ILE n 
1 286 GLN n 
1 287 ASN n 
1 288 HIS n 
1 289 PRO n 
1 290 TRP n 
1 291 MET n 
1 292 GLN n 
1 293 ASP n 
1 294 VAL n 
1 295 LEU n 
1 296 LEU n 
1 297 PRO n 
1 298 GLN n 
1 299 GLU n 
1 300 THR n 
1 301 ALA n 
1 302 GLU n 
1 303 ILE n 
1 304 HIS n 
1 305 LEU n 
1 306 HIS n 
1 307 SER n 
1 308 LEU n 
1 309 SER n 
1 310 PRO n 
1 311 GLY n 
1 312 PRO n 
1 313 SER n 
2 1   ALA n 
2 2   ARG n 
2 3   LYS n 
2 4   ARG n 
2 5   ARG n 
2 6   ARG n 
2 7   HIS n 
2 8   PRO n 
2 9   SER n 
2 10  GLY n 
2 11  PRO n 
2 12  PRO n 
2 13  THR n 
2 14  ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   313 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PIM1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          pLIC-SGC 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       14 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                             ?                                               
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                            ?                                               
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                          ?                                               
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                     ?                                               
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                            ?                                               
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                           ?                                               
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                     ?                                               
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                             ?                                               
'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                                            'GLYCERIN; PROPANE-1,2,3-TRIOL'                 
'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                                           ?                                               
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                               ?                                               
'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                          ?                                               
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                             ?                                               
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                              ?                                               
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                          ?                                               
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                       ?                                               
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                             ?                                               
'C5 H9 N O2'     115.130 
SEP 'L-peptide linking' n PHOSPHOSERINE                                       PHOSPHONOSERINE                                 
'C3 H8 N O6 P'   185.072 
SER 'L-peptide linking' y SERINE                                              ?                                               
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                           ?                                               
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                          ?                                               
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                            ?                                               
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                              ?                                               
'C5 H11 N O2'    117.146 
XJL non-polymer         . '4-(5-(4-aminophenyl)-1H-pyrazol-1-yl)benzoic acid' '4-[5-(4-aminophenyl)pyrazol-1-yl]benzoic acid' 
'C16 H13 N3 O2'  279.293 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   0   ?   ?   ?   A . n 
A 1 2   MET 2   1   ?   ?   ?   A . n 
A 1 3   LEU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   SER 5   4   ?   ?   ?   A . n 
A 1 6   LYS 6   5   ?   ?   ?   A . n 
A 1 7   ILE 7   6   ?   ?   ?   A . n 
A 1 8   ASN 8   7   ?   ?   ?   A . n 
A 1 9   SER 9   8   ?   ?   ?   A . n 
A 1 10  LEU 10  9   ?   ?   ?   A . n 
A 1 11  ALA 11  10  ?   ?   ?   A . n 
A 1 12  HIS 12  11  ?   ?   ?   A . n 
A 1 13  LEU 13  12  ?   ?   ?   A . n 
A 1 14  ARG 14  13  ?   ?   ?   A . n 
A 1 15  ALA 15  14  ?   ?   ?   A . n 
A 1 16  ALA 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  CYS 18  17  ?   ?   ?   A . n 
A 1 19  ASN 19  18  ?   ?   ?   A . n 
A 1 20  ASP 20  19  ?   ?   ?   A . n 
A 1 21  LEU 21  20  ?   ?   ?   A . n 
A 1 22  HIS 22  21  ?   ?   ?   A . n 
A 1 23  ALA 23  22  ?   ?   ?   A . n 
A 1 24  THR 24  23  ?   ?   ?   A . n 
A 1 25  LYS 25  24  ?   ?   ?   A . n 
A 1 26  LEU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  PRO 28  27  ?   ?   ?   A . n 
A 1 29  GLY 29  28  ?   ?   ?   A . n 
A 1 30  LYS 30  29  ?   ?   ?   A . n 
A 1 31  GLU 31  30  ?   ?   ?   A . n 
A 1 32  LYS 32  31  ?   ?   ?   A . n 
A 1 33  GLU 33  32  ?   ?   ?   A . n 
A 1 34  PRO 34  33  33  PRO PRO A . n 
A 1 35  LEU 35  34  34  LEU LEU A . n 
A 1 36  GLU 36  35  35  GLU GLU A . n 
A 1 37  SER 37  36  36  SER SER A . n 
A 1 38  GLN 38  37  37  GLN GLN A . n 
A 1 39  TYR 39  38  38  TYR TYR A . n 
A 1 40  GLN 40  39  39  GLN GLN A . n 
A 1 41  VAL 41  40  40  VAL VAL A . n 
A 1 42  GLY 42  41  41  GLY GLY A . n 
A 1 43  PRO 43  42  42  PRO PRO A . n 
A 1 44  LEU 44  43  43  LEU LEU A . n 
A 1 45  LEU 45  44  44  LEU LEU A . n 
A 1 46  GLY 46  45  45  GLY GLY A . n 
A 1 47  SER 47  46  46  SER SER A . n 
A 1 48  GLY 48  47  47  GLY GLY A . n 
A 1 49  GLY 49  48  48  GLY GLY A . n 
A 1 50  PHE 50  49  49  PHE PHE A . n 
A 1 51  GLY 51  50  50  GLY GLY A . n 
A 1 52  SER 52  51  51  SER SER A . n 
A 1 53  VAL 53  52  52  VAL VAL A . n 
A 1 54  TYR 54  53  53  TYR TYR A . n 
A 1 55  SER 55  54  54  SER SER A . n 
A 1 56  GLY 56  55  55  GLY GLY A . n 
A 1 57  ILE 57  56  56  ILE ILE A . n 
A 1 58  ARG 58  57  57  ARG ARG A . n 
A 1 59  VAL 59  58  58  VAL VAL A . n 
A 1 60  SER 60  59  59  SER SER A . n 
A 1 61  ASP 61  60  60  ASP ASP A . n 
A 1 62  ASN 62  61  61  ASN ASN A . n 
A 1 63  LEU 63  62  62  LEU LEU A . n 
A 1 64  PRO 64  63  63  PRO PRO A . n 
A 1 65  VAL 65  64  64  VAL VAL A . n 
A 1 66  ALA 66  65  65  ALA ALA A . n 
A 1 67  ILE 67  66  66  ILE ILE A . n 
A 1 68  LYS 68  67  67  LYS LYS A . n 
A 1 69  HIS 69  68  68  HIS HIS A . n 
A 1 70  VAL 70  69  69  VAL VAL A . n 
A 1 71  GLU 71  70  70  GLU GLU A . n 
A 1 72  LYS 72  71  71  LYS LYS A . n 
A 1 73  ASP 73  72  72  ASP ASP A . n 
A 1 74  ARG 74  73  73  ARG ARG A . n 
A 1 75  ILE 75  74  74  ILE ILE A . n 
A 1 76  SER 76  75  75  SER SER A . n 
A 1 77  ASP 77  76  76  ASP ASP A . n 
A 1 78  TRP 78  77  77  TRP TRP A . n 
A 1 79  GLY 79  78  78  GLY GLY A . n 
A 1 80  GLU 80  79  79  GLU GLU A . n 
A 1 81  LEU 81  80  80  LEU LEU A . n 
A 1 82  PRO 82  81  81  PRO PRO A . n 
A 1 83  ASN 83  82  82  ASN ASN A . n 
A 1 84  GLY 84  83  83  GLY GLY A . n 
A 1 85  THR 85  84  84  THR THR A . n 
A 1 86  ARG 86  85  85  ARG ARG A . n 
A 1 87  VAL 87  86  86  VAL VAL A . n 
A 1 88  PRO 88  87  87  PRO PRO A . n 
A 1 89  MET 89  88  88  MET MET A . n 
A 1 90  GLU 90  89  89  GLU GLU A . n 
A 1 91  VAL 91  90  90  VAL VAL A . n 
A 1 92  VAL 92  91  91  VAL VAL A . n 
A 1 93  LEU 93  92  92  LEU LEU A . n 
A 1 94  LEU 94  93  93  LEU LEU A . n 
A 1 95  LYS 95  94  94  LYS LYS A . n 
A 1 96  LYS 96  95  95  LYS LYS A . n 
A 1 97  VAL 97  96  96  VAL VAL A . n 
A 1 98  SER 98  97  97  SER SER A . n 
A 1 99  SER 99  98  98  SER SER A . n 
A 1 100 GLY 100 99  99  GLY GLY A . n 
A 1 101 PHE 101 100 100 PHE PHE A . n 
A 1 102 SER 102 101 101 SER SER A . n 
A 1 103 GLY 103 102 102 GLY GLY A . n 
A 1 104 VAL 104 103 103 VAL VAL A . n 
A 1 105 ILE 105 104 104 ILE ILE A . n 
A 1 106 ARG 106 105 105 ARG ARG A . n 
A 1 107 LEU 107 106 106 LEU LEU A . n 
A 1 108 LEU 108 107 107 LEU LEU A . n 
A 1 109 ASP 109 108 108 ASP ASP A . n 
A 1 110 TRP 110 109 109 TRP TRP A . n 
A 1 111 PHE 111 110 110 PHE PHE A . n 
A 1 112 GLU 112 111 111 GLU GLU A . n 
A 1 113 ARG 113 112 112 ARG ARG A . n 
A 1 114 PRO 114 113 113 PRO PRO A . n 
A 1 115 ASP 115 114 114 ASP ASP A . n 
A 1 116 SER 116 115 115 SER SER A . n 
A 1 117 PHE 117 116 116 PHE PHE A . n 
A 1 118 VAL 118 117 117 VAL VAL A . n 
A 1 119 LEU 119 118 118 LEU LEU A . n 
A 1 120 ILE 120 119 119 ILE ILE A . n 
A 1 121 LEU 121 120 120 LEU LEU A . n 
A 1 122 GLU 122 121 121 GLU GLU A . n 
A 1 123 ARG 123 122 122 ARG ARG A . n 
A 1 124 PRO 124 123 123 PRO PRO A . n 
A 1 125 GLU 125 124 124 GLU GLU A . n 
A 1 126 PRO 126 125 125 PRO PRO A . n 
A 1 127 VAL 127 126 126 VAL VAL A . n 
A 1 128 GLN 128 127 127 GLN GLN A . n 
A 1 129 ASP 129 128 128 ASP ASP A . n 
A 1 130 LEU 130 129 129 LEU LEU A . n 
A 1 131 PHE 131 130 130 PHE PHE A . n 
A 1 132 ASP 132 131 131 ASP ASP A . n 
A 1 133 PHE 133 132 132 PHE PHE A . n 
A 1 134 ILE 134 133 133 ILE ILE A . n 
A 1 135 THR 135 134 134 THR THR A . n 
A 1 136 GLU 136 135 135 GLU GLU A . n 
A 1 137 ARG 137 136 136 ARG ARG A . n 
A 1 138 GLY 138 137 137 GLY GLY A . n 
A 1 139 ALA 139 138 138 ALA ALA A . n 
A 1 140 LEU 140 139 139 LEU LEU A . n 
A 1 141 GLN 141 140 140 GLN GLN A . n 
A 1 142 GLU 142 141 141 GLU GLU A . n 
A 1 143 GLU 143 142 142 GLU GLU A . n 
A 1 144 LEU 144 143 143 LEU LEU A . n 
A 1 145 ALA 145 144 144 ALA ALA A . n 
A 1 146 ARG 146 145 145 ARG ARG A . n 
A 1 147 SER 147 146 146 SER SER A . n 
A 1 148 PHE 148 147 147 PHE PHE A . n 
A 1 149 PHE 149 148 148 PHE PHE A . n 
A 1 150 TRP 150 149 149 TRP TRP A . n 
A 1 151 GLN 151 150 150 GLN GLN A . n 
A 1 152 VAL 152 151 151 VAL VAL A . n 
A 1 153 LEU 153 152 152 LEU LEU A . n 
A 1 154 GLU 154 153 153 GLU GLU A . n 
A 1 155 ALA 155 154 154 ALA ALA A . n 
A 1 156 VAL 156 155 155 VAL VAL A . n 
A 1 157 ARG 157 156 156 ARG ARG A . n 
A 1 158 HIS 158 157 157 HIS HIS A . n 
A 1 159 CYS 159 158 158 CYS CYS A . n 
A 1 160 HIS 160 159 159 HIS HIS A . n 
A 1 161 ASN 161 160 160 ASN ASN A . n 
A 1 162 CYS 162 161 161 CYS CYS A . n 
A 1 163 GLY 163 162 162 GLY GLY A . n 
A 1 164 VAL 164 163 163 VAL VAL A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 HIS 166 165 165 HIS HIS A . n 
A 1 167 ARG 167 166 166 ARG ARG A . n 
A 1 168 ASP 168 167 167 ASP ASP A . n 
A 1 169 ILE 169 168 168 ILE ILE A . n 
A 1 170 LYS 170 169 169 LYS LYS A . n 
A 1 171 ASP 171 170 170 ASP ASP A . n 
A 1 172 GLU 172 171 171 GLU GLU A . n 
A 1 173 ASN 173 172 172 ASN ASN A . n 
A 1 174 ILE 174 173 173 ILE ILE A . n 
A 1 175 LEU 175 174 174 LEU LEU A . n 
A 1 176 ILE 176 175 175 ILE ILE A . n 
A 1 177 ASP 177 176 176 ASP ASP A . n 
A 1 178 LEU 178 177 177 LEU LEU A . n 
A 1 179 ASN 179 178 178 ASN ASN A . n 
A 1 180 ARG 180 179 179 ARG ARG A . n 
A 1 181 GLY 181 180 180 GLY GLY A . n 
A 1 182 GLU 182 181 181 GLU GLU A . n 
A 1 183 LEU 183 182 182 LEU LEU A . n 
A 1 184 LYS 184 183 183 LYS LYS A . n 
A 1 185 LEU 185 184 184 LEU LEU A . n 
A 1 186 ILE 186 185 185 ILE ILE A . n 
A 1 187 ASP 187 186 186 ASP ASP A . n 
A 1 188 PHE 188 187 187 PHE PHE A . n 
A 1 189 GLY 189 188 188 GLY GLY A . n 
A 1 190 SER 190 189 189 SER SER A . n 
A 1 191 GLY 191 190 190 GLY GLY A . n 
A 1 192 ALA 192 191 191 ALA ALA A . n 
A 1 193 LEU 193 192 192 LEU LEU A . n 
A 1 194 LEU 194 193 193 LEU LEU A . n 
A 1 195 LYS 195 194 194 LYS LYS A . n 
A 1 196 ASP 196 195 195 ASP ASP A . n 
A 1 197 THR 197 196 196 THR THR A . n 
A 1 198 VAL 198 197 197 VAL VAL A . n 
A 1 199 TYR 199 198 198 TYR TYR A . n 
A 1 200 THR 200 199 199 THR THR A . n 
A 1 201 ASP 201 200 200 ASP ASP A . n 
A 1 202 PHE 202 201 201 PHE PHE A . n 
A 1 203 ASP 203 202 202 ASP ASP A . n 
A 1 204 GLY 204 203 203 GLY GLY A . n 
A 1 205 THR 205 204 204 THR THR A . n 
A 1 206 ARG 206 205 205 ARG ARG A . n 
A 1 207 VAL 207 206 206 VAL VAL A . n 
A 1 208 TYR 208 207 207 TYR TYR A . n 
A 1 209 SER 209 208 208 SER SER A . n 
A 1 210 PRO 210 209 209 PRO PRO A . n 
A 1 211 PRO 211 210 210 PRO PRO A . n 
A 1 212 GLU 212 211 211 GLU GLU A . n 
A 1 213 TRP 213 212 212 TRP TRP A . n 
A 1 214 ILE 214 213 213 ILE ILE A . n 
A 1 215 ARG 215 214 214 ARG ARG A . n 
A 1 216 TYR 216 215 215 TYR TYR A . n 
A 1 217 HIS 217 216 216 HIS HIS A . n 
A 1 218 ARG 218 217 217 ARG ARG A . n 
A 1 219 TYR 219 218 218 TYR TYR A . n 
A 1 220 HIS 220 219 219 HIS HIS A . n 
A 1 221 GLY 221 220 220 GLY GLY A . n 
A 1 222 ARG 222 221 221 ARG ARG A . n 
A 1 223 SER 223 222 222 SER SER A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 ALA 225 224 224 ALA ALA A . n 
A 1 226 VAL 226 225 225 VAL VAL A . n 
A 1 227 TRP 227 226 226 TRP TRP A . n 
A 1 228 SER 228 227 227 SER SER A . n 
A 1 229 LEU 229 228 228 LEU LEU A . n 
A 1 230 GLY 230 229 229 GLY GLY A . n 
A 1 231 ILE 231 230 230 ILE ILE A . n 
A 1 232 LEU 232 231 231 LEU LEU A . n 
A 1 233 LEU 233 232 232 LEU LEU A . n 
A 1 234 TYR 234 233 233 TYR TYR A . n 
A 1 235 ASP 235 234 234 ASP ASP A . n 
A 1 236 MET 236 235 235 MET MET A . n 
A 1 237 VAL 237 236 236 VAL VAL A . n 
A 1 238 CYS 238 237 237 CYS CYS A . n 
A 1 239 GLY 239 238 238 GLY GLY A . n 
A 1 240 ASP 240 239 239 ASP ASP A . n 
A 1 241 ILE 241 240 240 ILE ILE A . n 
A 1 242 PRO 242 241 241 PRO PRO A . n 
A 1 243 PHE 243 242 242 PHE PHE A . n 
A 1 244 GLU 244 243 243 GLU GLU A . n 
A 1 245 HIS 245 244 244 HIS HIS A . n 
A 1 246 ASP 246 245 245 ASP ASP A . n 
A 1 247 GLU 247 246 246 GLU GLU A . n 
A 1 248 GLU 248 247 247 GLU GLU A . n 
A 1 249 ILE 249 248 248 ILE ILE A . n 
A 1 250 ILE 250 249 249 ILE ILE A . n 
A 1 251 GLY 251 250 250 GLY GLY A . n 
A 1 252 GLY 252 251 251 GLY GLY A . n 
A 1 253 GLN 253 252 252 GLN GLN A . n 
A 1 254 VAL 254 253 253 VAL VAL A . n 
A 1 255 PHE 255 254 254 PHE PHE A . n 
A 1 256 PHE 256 255 255 PHE PHE A . n 
A 1 257 ARG 257 256 256 ARG ARG A . n 
A 1 258 GLN 258 257 257 GLN GLN A . n 
A 1 259 ARG 259 258 258 ARG ARG A . n 
A 1 260 VAL 260 259 259 VAL VAL A . n 
A 1 261 SER 261 260 260 SER SER A . n 
A 1 262 SEP 262 261 261 SEP SEP A . n 
A 1 263 GLU 263 262 262 GLU GLU A . n 
A 1 264 CYS 264 263 263 CYS CYS A . n 
A 1 265 GLN 265 264 264 GLN GLN A . n 
A 1 266 HIS 266 265 265 HIS HIS A . n 
A 1 267 LEU 267 266 266 LEU LEU A . n 
A 1 268 ILE 268 267 267 ILE ILE A . n 
A 1 269 ARG 269 268 268 ARG ARG A . n 
A 1 270 TRP 270 269 269 TRP TRP A . n 
A 1 271 CYS 271 270 270 CYS CYS A . n 
A 1 272 LEU 272 271 271 LEU LEU A . n 
A 1 273 ALA 273 272 272 ALA ALA A . n 
A 1 274 LEU 274 273 273 LEU LEU A . n 
A 1 275 ARG 275 274 274 ARG ARG A . n 
A 1 276 PRO 276 275 275 PRO PRO A . n 
A 1 277 SER 277 276 276 SER SER A . n 
A 1 278 ASP 278 277 277 ASP ASP A . n 
A 1 279 ARG 279 278 278 ARG ARG A . n 
A 1 280 PRO 280 279 279 PRO PRO A . n 
A 1 281 THR 281 280 280 THR THR A . n 
A 1 282 PHE 282 281 281 PHE PHE A . n 
A 1 283 GLU 283 282 282 GLU GLU A . n 
A 1 284 GLU 284 283 283 GLU GLU A . n 
A 1 285 ILE 285 284 284 ILE ILE A . n 
A 1 286 GLN 286 285 285 GLN GLN A . n 
A 1 287 ASN 287 286 286 ASN ASN A . n 
A 1 288 HIS 288 287 287 HIS HIS A . n 
A 1 289 PRO 289 288 288 PRO PRO A . n 
A 1 290 TRP 290 289 289 TRP TRP A . n 
A 1 291 MET 291 290 290 MET MET A . n 
A 1 292 GLN 292 291 291 GLN GLN A . n 
A 1 293 ASP 293 292 292 ASP ASP A . n 
A 1 294 VAL 294 293 293 VAL VAL A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 LEU 296 295 295 LEU LEU A . n 
A 1 297 PRO 297 296 296 PRO PRO A . n 
A 1 298 GLN 298 297 297 GLN GLN A . n 
A 1 299 GLU 299 298 298 GLU GLU A . n 
A 1 300 THR 300 299 299 THR THR A . n 
A 1 301 ALA 301 300 300 ALA ALA A . n 
A 1 302 GLU 302 301 301 GLU GLU A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 HIS 304 303 303 HIS HIS A . n 
A 1 305 LEU 305 304 304 LEU LEU A . n 
A 1 306 HIS 306 305 305 HIS HIS A . n 
A 1 307 SER 307 306 ?   ?   ?   A . n 
A 1 308 LEU 308 307 ?   ?   ?   A . n 
A 1 309 SER 309 308 ?   ?   ?   A . n 
A 1 310 PRO 310 309 ?   ?   ?   A . n 
A 1 311 GLY 311 310 ?   ?   ?   A . n 
A 1 312 PRO 312 311 ?   ?   ?   A . n 
A 1 313 SER 313 312 ?   ?   ?   A . n 
B 2 1   ALA 1   1   ?   ?   ?   B . n 
B 2 2   ARG 2   2   2   ARG ARG B . n 
B 2 3   LYS 3   3   3   LYS LYS B . n 
B 2 4   ARG 4   4   4   ARG ARG B . n 
B 2 5   ARG 5   5   5   ARG ARG B . n 
B 2 6   ARG 6   6   6   ARG ARG B . n 
B 2 7   HIS 7   7   7   HIS HIS B . n 
B 2 8   PRO 8   8   8   PRO PRO B . n 
B 2 9   SER 9   9   9   SER SER B . n 
B 2 10  GLY 10  10  10  GLY GLY B . n 
B 2 11  PRO 11  11  ?   ?   ?   B . n 
B 2 12  PRO 12  12  ?   ?   ?   B . n 
B 2 13  THR 13  13  ?   ?   ?   B . n 
B 2 14  ALA 14  14  ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XJL 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XJL 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 GOL 1  401 1   GOL GOL A . 
D 4 XJL 1  402 1   XJL 577 A . 
E 5 HOH 1  501 102 HOH HOH A . 
E 5 HOH 2  502 124 HOH HOH A . 
E 5 HOH 3  503 12  HOH HOH A . 
E 5 HOH 4  504 76  HOH HOH A . 
E 5 HOH 5  505 115 HOH HOH A . 
E 5 HOH 6  506 58  HOH HOH A . 
E 5 HOH 7  507 71  HOH HOH A . 
E 5 HOH 8  508 45  HOH HOH A . 
E 5 HOH 9  509 28  HOH HOH A . 
E 5 HOH 10 510 29  HOH HOH A . 
E 5 HOH 11 511 8   HOH HOH A . 
E 5 HOH 12 512 57  HOH HOH A . 
E 5 HOH 13 513 26  HOH HOH A . 
E 5 HOH 14 514 27  HOH HOH A . 
E 5 HOH 15 515 31  HOH HOH A . 
E 5 HOH 16 516 40  HOH HOH A . 
E 5 HOH 17 517 96  HOH HOH A . 
E 5 HOH 18 518 117 HOH HOH A . 
E 5 HOH 19 519 35  HOH HOH A . 
E 5 HOH 20 520 2   HOH HOH A . 
E 5 HOH 21 521 104 HOH HOH A . 
E 5 HOH 22 522 37  HOH HOH A . 
E 5 HOH 23 523 5   HOH HOH A . 
E 5 HOH 24 524 56  HOH HOH A . 
E 5 HOH 25 525 47  HOH HOH A . 
E 5 HOH 26 526 17  HOH HOH A . 
E 5 HOH 27 527 101 HOH HOH A . 
E 5 HOH 28 528 80  HOH HOH A . 
E 5 HOH 29 529 22  HOH HOH A . 
E 5 HOH 30 530 63  HOH HOH A . 
E 5 HOH 31 531 114 HOH HOH A . 
E 5 HOH 32 532 50  HOH HOH A . 
E 5 HOH 33 533 113 HOH HOH A . 
E 5 HOH 34 534 13  HOH HOH A . 
E 5 HOH 35 535 84  HOH HOH A . 
E 5 HOH 36 536 4   HOH HOH A . 
E 5 HOH 37 537 48  HOH HOH A . 
E 5 HOH 38 538 105 HOH HOH A . 
E 5 HOH 39 539 3   HOH HOH A . 
E 5 HOH 40 540 87  HOH HOH A . 
E 5 HOH 41 541 85  HOH HOH A . 
E 5 HOH 42 542 111 HOH HOH A . 
E 5 HOH 43 543 95  HOH HOH A . 
E 5 HOH 44 544 33  HOH HOH A . 
E 5 HOH 45 545 6   HOH HOH A . 
E 5 HOH 46 546 93  HOH HOH A . 
E 5 HOH 47 547 90  HOH HOH A . 
E 5 HOH 48 548 103 HOH HOH A . 
E 5 HOH 49 549 36  HOH HOH A . 
E 5 HOH 50 550 120 HOH HOH A . 
E 5 HOH 51 551 25  HOH HOH A . 
E 5 HOH 52 552 123 HOH HOH A . 
E 5 HOH 53 553 98  HOH HOH A . 
E 5 HOH 54 554 21  HOH HOH A . 
E 5 HOH 55 555 77  HOH HOH A . 
E 5 HOH 56 556 7   HOH HOH A . 
E 5 HOH 57 557 94  HOH HOH A . 
E 5 HOH 58 558 14  HOH HOH A . 
E 5 HOH 59 559 18  HOH HOH A . 
E 5 HOH 60 560 20  HOH HOH A . 
E 5 HOH 61 561 39  HOH HOH A . 
E 5 HOH 62 562 83  HOH HOH A . 
E 5 HOH 63 563 121 HOH HOH A . 
E 5 HOH 64 564 32  HOH HOH A . 
E 5 HOH 65 565 109 HOH HOH A . 
E 5 HOH 66 566 82  HOH HOH A . 
E 5 HOH 67 567 110 HOH HOH A . 
E 5 HOH 68 568 24  HOH HOH A . 
E 5 HOH 69 569 10  HOH HOH A . 
E 5 HOH 70 570 97  HOH HOH A . 
E 5 HOH 71 571 38  HOH HOH A . 
E 5 HOH 72 572 60  HOH HOH A . 
E 5 HOH 73 573 100 HOH HOH A . 
E 5 HOH 74 574 122 HOH HOH A . 
E 5 HOH 75 575 89  HOH HOH A . 
E 5 HOH 76 576 11  HOH HOH A . 
E 5 HOH 77 577 46  HOH HOH A . 
E 5 HOH 78 578 91  HOH HOH A . 
E 5 HOH 79 579 15  HOH HOH A . 
E 5 HOH 80 580 51  HOH HOH A . 
E 5 HOH 81 581 34  HOH HOH A . 
E 5 HOH 82 582 99  HOH HOH A . 
E 5 HOH 83 583 62  HOH HOH A . 
E 5 HOH 84 584 70  HOH HOH A . 
E 5 HOH 85 585 106 HOH HOH A . 
E 5 HOH 86 586 41  HOH HOH A . 
E 5 HOH 87 587 9   HOH HOH A . 
E 5 HOH 88 588 16  HOH HOH A . 
E 5 HOH 89 589 72  HOH HOH A . 
E 5 HOH 90 590 81  HOH HOH A . 
E 5 HOH 91 591 23  HOH HOH A . 
E 5 HOH 92 592 52  HOH HOH A . 
E 5 HOH 93 593 88  HOH HOH A . 
E 5 HOH 94 594 44  HOH HOH A . 
E 5 HOH 95 595 65  HOH HOH A . 
E 5 HOH 96 596 49  HOH HOH A . 
E 5 HOH 97 597 119 HOH HOH A . 
E 5 HOH 98 598 64  HOH HOH A . 
F 5 HOH 1  101 30  HOH HOH B . 
F 5 HOH 2  102 112 HOH HOH B . 
F 5 HOH 3  103 74  HOH HOH B . 
F 5 HOH 4  104 92  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LEU 34  ? CG  ? A LEU 35  CG  
2  1 Y 1 A LEU 34  ? CD1 ? A LEU 35  CD1 
3  1 Y 1 A LEU 34  ? CD2 ? A LEU 35  CD2 
4  1 Y 1 A GLU 35  ? CG  ? A GLU 36  CG  
5  1 Y 1 A GLU 35  ? CD  ? A GLU 36  CD  
6  1 Y 1 A GLU 35  ? OE1 ? A GLU 36  OE1 
7  1 Y 1 A GLU 35  ? OE2 ? A GLU 36  OE2 
8  1 Y 1 A SER 36  ? OG  ? A SER 37  OG  
9  1 Y 1 A GLN 39  ? CD  ? A GLN 40  CD  
10 1 Y 1 A GLN 39  ? OE1 ? A GLN 40  OE1 
11 1 Y 1 A GLN 39  ? NE2 ? A GLN 40  NE2 
12 1 Y 1 A PHE 49  ? CG  ? A PHE 50  CG  
13 1 Y 1 A PHE 49  ? CD1 ? A PHE 50  CD1 
14 1 Y 1 A PHE 49  ? CD2 ? A PHE 50  CD2 
15 1 Y 1 A PHE 49  ? CE1 ? A PHE 50  CE1 
16 1 Y 1 A PHE 49  ? CE2 ? A PHE 50  CE2 
17 1 Y 1 A PHE 49  ? CZ  ? A PHE 50  CZ  
18 1 Y 1 A ILE 56  ? CG2 ? A ILE 57  CG2 
19 1 Y 1 A ILE 56  ? CD1 ? A ILE 57  CD1 
20 1 Y 1 A VAL 58  ? CG1 ? A VAL 59  CG1 
21 1 Y 1 A VAL 58  ? CG2 ? A VAL 59  CG2 
22 1 Y 1 A SER 59  ? OG  ? A SER 60  OG  
23 1 Y 1 A LEU 62  ? CD1 ? A LEU 63  CD1 
24 1 Y 1 A LEU 62  ? CD2 ? A LEU 63  CD2 
25 1 Y 1 A ARG 73  ? CG  ? A ARG 74  CG  
26 1 Y 1 A ARG 73  ? CD  ? A ARG 74  CD  
27 1 Y 1 A ARG 73  ? NE  ? A ARG 74  NE  
28 1 Y 1 A ARG 73  ? CZ  ? A ARG 74  CZ  
29 1 Y 1 A ARG 73  ? NH1 ? A ARG 74  NH1 
30 1 Y 1 A ARG 73  ? NH2 ? A ARG 74  NH2 
31 1 Y 1 A SER 75  ? OG  ? A SER 76  OG  
32 1 Y 1 A ASP 76  ? OD1 ? A ASP 77  OD1 
33 1 Y 1 A ASP 76  ? OD2 ? A ASP 77  OD2 
34 1 Y 1 A GLU 79  ? CG  ? A GLU 80  CG  
35 1 Y 1 A GLU 79  ? CD  ? A GLU 80  CD  
36 1 Y 1 A GLU 79  ? OE1 ? A GLU 80  OE1 
37 1 Y 1 A GLU 79  ? OE2 ? A GLU 80  OE2 
38 1 Y 1 A LEU 80  ? CG  ? A LEU 81  CG  
39 1 Y 1 A LEU 80  ? CD1 ? A LEU 81  CD1 
40 1 Y 1 A LEU 80  ? CD2 ? A LEU 81  CD2 
41 1 Y 1 A ASN 82  ? CG  ? A ASN 83  CG  
42 1 Y 1 A ASN 82  ? OD1 ? A ASN 83  OD1 
43 1 Y 1 A ASN 82  ? ND2 ? A ASN 83  ND2 
44 1 Y 1 A THR 84  ? OG1 ? A THR 85  OG1 
45 1 Y 1 A THR 84  ? CG2 ? A THR 85  CG2 
46 1 Y 1 A ARG 85  ? CG  ? A ARG 86  CG  
47 1 Y 1 A ARG 85  ? CD  ? A ARG 86  CD  
48 1 Y 1 A ARG 85  ? NE  ? A ARG 86  NE  
49 1 Y 1 A ARG 85  ? CZ  ? A ARG 86  CZ  
50 1 Y 1 A ARG 85  ? NH1 ? A ARG 86  NH1 
51 1 Y 1 A ARG 85  ? NH2 ? A ARG 86  NH2 
52 1 Y 1 A LYS 94  ? CE  ? A LYS 95  CE  
53 1 Y 1 A LYS 94  ? NZ  ? A LYS 95  NZ  
54 1 Y 1 A SER 97  ? OG  ? A SER 98  OG  
55 1 Y 1 A SER 98  ? OG  ? A SER 99  OG  
56 1 Y 1 A SER 101 ? OG  ? A SER 102 OG  
57 1 Y 1 A ARG 105 ? CD  ? A ARG 106 CD  
58 1 Y 1 A ARG 105 ? NE  ? A ARG 106 NE  
59 1 Y 1 A ARG 105 ? CZ  ? A ARG 106 CZ  
60 1 Y 1 A ARG 105 ? NH1 ? A ARG 106 NH1 
61 1 Y 1 A ARG 105 ? NH2 ? A ARG 106 NH2 
62 1 Y 1 A GLU 124 ? OE2 ? A GLU 125 OE2 
63 1 Y 1 A ARG 179 ? CZ  ? A ARG 180 CZ  
64 1 Y 1 A ARG 179 ? NH1 ? A ARG 180 NH1 
65 1 Y 1 A ARG 179 ? NH2 ? A ARG 180 NH2 
66 1 Y 1 A ASP 202 ? CG  ? A ASP 203 CG  
67 1 Y 1 A ASP 202 ? OD1 ? A ASP 203 OD1 
68 1 Y 1 A ASP 202 ? OD2 ? A ASP 203 OD2 
69 1 Y 1 A ARG 214 ? NE  ? A ARG 215 NE  
70 1 Y 1 A ARG 214 ? CZ  ? A ARG 215 CZ  
71 1 Y 1 A ARG 214 ? NH1 ? A ARG 215 NH1 
72 1 Y 1 A ARG 214 ? NH2 ? A ARG 215 NH2 
73 1 Y 1 A GLN 252 ? CG  ? A GLN 253 CG  
74 1 Y 1 A GLN 252 ? CD  ? A GLN 253 CD  
75 1 Y 1 A GLN 252 ? OE1 ? A GLN 253 OE1 
76 1 Y 1 A GLN 252 ? NE2 ? A GLN 253 NE2 
77 1 Y 1 A ARG 274 ? CG  ? A ARG 275 CG  
78 1 Y 1 A ARG 274 ? CD  ? A ARG 275 CD  
79 1 Y 1 A ARG 274 ? NE  ? A ARG 275 NE  
80 1 Y 1 A ARG 274 ? CZ  ? A ARG 275 CZ  
81 1 Y 1 A ARG 274 ? NH1 ? A ARG 275 NH1 
82 1 Y 1 A ARG 274 ? NH2 ? A ARG 275 NH2 
83 1 Y 1 A GLN 297 ? CG  ? A GLN 298 CG  
84 1 Y 1 A GLN 297 ? CD  ? A GLN 298 CD  
85 1 Y 1 A GLN 297 ? OE1 ? A GLN 298 OE1 
86 1 Y 1 A GLN 297 ? NE2 ? A GLN 298 NE2 
87 1 Y 1 B LYS 3   ? CD  ? B LYS 3   CD  
88 1 Y 1 B LYS 3   ? CE  ? B LYS 3   CE  
89 1 Y 1 B LYS 3   ? NZ  ? B LYS 3   NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? MxCuBE ? ? ? .           1 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 2 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 3.1.9       3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 3.1.9       4 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           5 
? 'model building'  ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? 0.7.1       6 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R25 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     98.352 
_cell.length_a_esd                 ? 
_cell.length_b                     98.352 
_cell.length_b_esd                 ? 
_cell.length_c                     80.228 
_cell.length_c_esd                 ? 
_cell.volume                       672083.122 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R25 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                170 
_symmetry.space_group_name_Hall            'P 65' 
_symmetry.space_group_name_H-M             'P 65' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R25 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.2 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          61.0 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'100 mM bis-tris-propane (pH 7.0), 10% ethylene glycol, 0.3% DMSO, 20% PEG3350, 200 mM Mg(OAc)2' 
_exptl_crystal_grow.pdbx_pH_range   6.8-7.2 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-05-29 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    'Double crystal' 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9184 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'BESSY BEAMLINE 14.1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9184 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   14.1 
_diffrn_source.pdbx_synchrotron_site       BESSY 
# 
_reflns.B_iso_Wilson_estimate                          41.69 
_reflns.entry_id                                       8R25 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.10 
_reflns.d_resolution_low                               49.18 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     25812 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          21.68 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.10 
_reflns_shell.d_res_low                                     2.11 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4144 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.94 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               49.52 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R25 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.10 
_refine.ls_d_res_low                             36.29 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     25778 
_refine.ls_number_reflns_R_free                  1287 
_refine.ls_number_reflns_R_work                  24491 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.83 
_refine.ls_percent_reflns_R_free                 4.99 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1782 
_refine.ls_R_factor_R_free                       0.2083 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1766 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.1687 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2239 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.10 
_refine_hist.d_res_low                        36.29 
_refine_hist.number_atoms_solvent             102 
_refine_hist.number_atoms_total               2341 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2212 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         27 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0025  ? 2300 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4812  ? 3126 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0428  ? 332  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0049  ? 425  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.3641 ? 836  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.10 2.18  . . 142 2708 99.51  . . . . 0.2302 . . . . . . . . . . . 0.2398 
'X-RAY DIFFRACTION' 2.18 2.28  . . 142 2694 99.75  . . . . 0.2016 . . . . . . . . . . . 0.2255 
'X-RAY DIFFRACTION' 2.28 2.40  . . 141 2692 99.79  . . . . 0.1860 . . . . . . . . . . . 0.2512 
'X-RAY DIFFRACTION' 2.40 2.55  . . 142 2703 99.93  . . . . 0.1886 . . . . . . . . . . . 0.2272 
'X-RAY DIFFRACTION' 2.55 2.75  . . 145 2746 99.90  . . . . 0.1973 . . . . . . . . . . . 0.2317 
'X-RAY DIFFRACTION' 2.75 3.03  . . 143 2721 99.93  . . . . 0.1826 . . . . . . . . . . . 0.2345 
'X-RAY DIFFRACTION' 3.03 3.47  . . 143 2713 100.00 . . . . 0.1813 . . . . . . . . . . . 0.2027 
'X-RAY DIFFRACTION' 3.47 4.37  . . 144 2739 100.00 . . . . 0.1588 . . . . . . . . . . . 0.1897 
'X-RAY DIFFRACTION' 4.37 36.29 . . 145 2775 99.79  . . . . 0.1699 . . . . . . . . . . . 0.1980 
# 
_struct.entry_id                     8R25 
_struct.title                        'Pim1 in complex with 4-(5-(4-aminophenyl)-1H-pyrazol-1-yl)benzoic acid and Pimtide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R25 
_struct_keywords.text            
;SERINE KINASE, KINASE, COMPLEX, PIM1, PIM, PIM-1, INHIBITOR, TUMORIGENISIS, CANCER, PIMTIDE, PROTO ONCOGEN, ATP, PHOSPHORYLATION, APOPTOSIS, CELL CYCLE, TRANSFERASE
;
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP PIM1_HUMAN P11309 P11309-1 1 
;MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL
PNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN
CGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
1 
2 PDB 8R25       8R25   ?        2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R25 A 2 ? 313 ? P11309 1 ? 312 ? 1 312 
2 2 8R25 B 1 ? 14  ? 8R25   1 ? 14  ? 1 14  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R25 SER A 1   ? UNP P11309 ?   ?   'expression tag'      0   1 
1 8R25 GLY A 251 ? UNP P11309 ARG 250 'engineered mutation' 250 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1400  ? 
1 MORE         2     ? 
1 'SSA (A^2)'  12770 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 34  ? GLN A 38  ? PRO A 33  GLN A 37  1 ? 5  
HELX_P HELX_P2  AA2 ASP A 73  ? ILE A 75  ? ASP A 72  ILE A 74  5 ? 3  
HELX_P HELX_P3  AA3 MET A 89  ? SER A 98  ? MET A 88  SER A 97  1 ? 10 
HELX_P HELX_P4  AA4 LEU A 130 ? GLY A 138 ? LEU A 129 GLY A 137 1 ? 9  
HELX_P HELX_P5  AA5 GLN A 141 ? CYS A 162 ? GLN A 140 CYS A 161 1 ? 22 
HELX_P HELX_P6  AA6 LYS A 170 ? GLU A 172 ? LYS A 169 GLU A 171 5 ? 3  
HELX_P HELX_P7  AA7 THR A 205 ? SER A 209 ? THR A 204 SER A 208 5 ? 5  
HELX_P HELX_P8  AA8 PRO A 210 ? HIS A 217 ? PRO A 209 HIS A 216 1 ? 8  
HELX_P HELX_P9  AA9 HIS A 220 ? GLY A 239 ? HIS A 219 GLY A 238 1 ? 20 
HELX_P HELX_P10 AB1 HIS A 245 ? GLY A 252 ? HIS A 244 GLY A 251 1 ? 8  
HELX_P HELX_P11 AB2 SER A 261 ? LEU A 272 ? SER A 260 LEU A 271 1 ? 12 
HELX_P HELX_P12 AB3 ARG A 275 ? ARG A 279 ? ARG A 274 ARG A 278 5 ? 5  
HELX_P HELX_P13 AB4 THR A 281 ? ASN A 287 ? THR A 280 ASN A 286 1 ? 7  
HELX_P HELX_P14 AB5 HIS A 288 ? GLN A 292 ? HIS A 287 GLN A 291 5 ? 5  
HELX_P HELX_P15 AB6 LEU A 296 ? LEU A 305 ? LEU A 295 LEU A 304 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A SER 261 C ? ? ? 1_555 A SEP 262 N ? ? A SER 260 A SEP 261 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale2 covale both ? A SEP 262 C ? ? ? 1_555 A GLU 263 N ? ? A SEP 261 A GLU 262 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      SEP 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       262 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       SEP 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        261 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                SER 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        SEP 
_pdbx_modification_feature.type                               Phosphorylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           125 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            124 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    126 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     125 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -5.83 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 39  ? GLY A 48  ? TYR A 38  GLY A 47  
AA1 2 GLY A 51  ? ARG A 58  ? GLY A 50  ARG A 57  
AA1 3 PRO A 64  ? GLU A 71  ? PRO A 63  GLU A 70  
AA1 4 SER A 116 ? GLU A 122 ? SER A 115 GLU A 121 
AA1 5 LEU A 107 ? ARG A 113 ? LEU A 106 ARG A 112 
AA2 1 TRP A 78  ? GLU A 80  ? TRP A 77  GLU A 79  
AA2 2 ARG A 86  ? PRO A 88  ? ARG A 85  PRO A 87  
AA3 1 VAL A 127 ? ASP A 129 ? VAL A 126 ASP A 128 
AA3 2 ILE A 174 ? ASP A 177 ? ILE A 173 ASP A 176 
AA3 3 GLU A 182 ? LEU A 185 ? GLU A 181 LEU A 184 
AA4 1 VAL A 164 ? LEU A 165 ? VAL A 163 LEU A 164 
AA4 2 ALA A 192 ? LEU A 193 ? ALA A 191 LEU A 192 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 42  ? N GLY A 41  O SER A 55  ? O SER A 54  
AA1 2 3 N TYR A 54  ? N TYR A 53  O ILE A 67  ? O ILE A 66  
AA1 3 4 N LYS A 68  ? N LYS A 67  O LEU A 119 ? O LEU A 118 
AA1 4 5 O ILE A 120 ? O ILE A 119 N LEU A 108 ? N LEU A 107 
AA2 1 2 N GLY A 79  ? N GLY A 78  O VAL A 87  ? O VAL A 86  
AA3 1 2 N GLN A 128 ? N GLN A 127 O ILE A 176 ? O ILE A 175 
AA3 2 3 N ASP A 177 ? N ASP A 176 O GLU A 182 ? O GLU A 181 
AA4 1 2 N LEU A 165 ? N LEU A 164 O ALA A 192 ? O ALA A 191 
# 
_pdbx_entry_details.entry_id                   8R25 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE A 49  ? ? -92.34  32.46 
2 1 ASP A 60  ? ? -152.37 15.39 
3 1 ASP A 167 ? ? -146.19 46.15 
4 1 ASP A 186 ? ? 56.41   81.80 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    SEP 
_pdbx_struct_mod_residue.label_seq_id     262 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     SEP 
_pdbx_struct_mod_residue.auth_seq_id      261 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   SER 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z         
2 x-y,x,z+5/6   
3 y,-x+y,z+1/6  
4 -y,x-y,z+2/3  
5 -x+y,-x,z+1/3 
6 -x,-y,z+1/2   
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -57.0638422477 -121.196886669 11.8872413561    0.634560969375 ? 0.062250864352   ? 0.117094916043 
? 0.498503214116 ? -0.0431059052746 ? 0.515869785757 ? 0.051021408916  ? -0.0553666174724  ? -0.0304871646456 ? 0.169351377939 ? 
-0.102176140454 ? 0.186446160757  ? 0.274691764584  ? -0.609210037058  ? 0.372322500795  ? 0.405218222139    ? -0.328488528278 ? 
-0.176943640172  ? -0.40644057563   ? 0.383450292216  ? -0.00296496542401 ? 
2 'X-RAY DIFFRACTION' ? refined -77.4537436648 -116.681788376 -5.25282658861   0.537924877439 ? 0.167999430412   ? 
-0.00407801980158 ? 0.900217202241 ? -0.053681316668  ? 0.744021958116 ? 0.0326779204973 ? 0.000697984394963 ? -0.0433070200572 ? 
0.231692964603 ? 0.0175121415921 ? 0.0592818765097 ? 0.105752964663  ? -0.143128026285  ? 0.206026753522  ? 0.441880486672    ? 
-0.240072136045 ? 0.555144968875   ? -0.375964293941  ? 0.237581487539  ? -0.00392926521356 ? 
3 'X-RAY DIFFRACTION' ? refined -68.0218387148 -115.242714244 -10.8142170248   0.408177009359 ? 0.0340315536463  ? 0.0417266981662 
? 0.476872520566 ? 0.0190394201744  ? 0.496234799152 ? 0.441562726781  ? -0.349201310321   ? 0.0747997411527  ? 0.378669594464 ? 
0.0145265131211 ? 0.513410958965  ? 0.280493609509  ? 0.0872850888468  ? 0.30355122235   ? -0.346537267101   ? -0.255587209963 ? 
0.11054523607    ? -0.441677665664  ? -0.210514342098 ? 5.08444771997e-05 ? 
4 'X-RAY DIFFRACTION' ? refined -67.6335084636 -124.229951192 -3.91946500102   0.320716984183 ? 0.00883926438008 ? 
-0.0036611964442  ? 0.541129945609 ? 0.01383027229    ? 0.446278280153 ? 0.410268557791  ? -0.219365032382   ? -0.297029521118  ? 
0.650055421996 ? 0.865846792905  ? 1.1522876216    ? 0.120637185917  ? -0.105949033548  ? -0.102625011974 ? -0.00417171472596 ? 
0.0800731333627 ? 0.486131651578   ? -0.0534928170451 ? -0.57999181146  ? 0.000220334365677 ? 
5 'X-RAY DIFFRACTION' ? refined -50.5117890849 -129.908932688 -0.0245475443725 0.303670915365 ? -0.0082027142741 ? 
0.00122378111069  ? 0.384110836414 ? -0.0362341968845 ? 0.340616753138 ? 1.1554963912    ? 0.133074312752    ? -0.35898497125   ? 
1.20894349046  ? -0.505102446365 ? 2.67885916725   ? 0.0422087944876 ? -0.0741420204703 ? 0.0385406457885 ? 0.0772409345621   ? 
0.0483918662758 ? 0.00104430694333 ? 0.0661708691925  ? 0.300011557081  ? -1.6493231428e-05 ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 C 1   B 2   ? C 9   B 10  ? ? 
;chain 'B' and (resid 2 through 10 )
;
2 'X-RAY DIFFRACTION' 2 A 1   A 33  ? A 17  A 49  ? ? 
;chain 'A' and (resid 33 through 49 )
;
3 'X-RAY DIFFRACTION' 3 A 18  A 50  ? A 64  A 96  ? ? 
;chain 'A' and (resid 50 through 96 )
;
4 'X-RAY DIFFRACTION' 4 A 65  A 97  ? A 108 A 140 ? ? 
;chain 'A' and (resid 97 through 140 )
;
5 'X-RAY DIFFRACTION' 5 A 109 A 141 ? A 273 A 305 ? ? 
;chain 'A' and (resid 141 through 305 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER 0   ? A SER 1   
2  1 Y 1 A MET 1   ? A MET 2   
3  1 Y 1 A LEU 2   ? A LEU 3   
4  1 Y 1 A LEU 3   ? A LEU 4   
5  1 Y 1 A SER 4   ? A SER 5   
6  1 Y 1 A LYS 5   ? A LYS 6   
7  1 Y 1 A ILE 6   ? A ILE 7   
8  1 Y 1 A ASN 7   ? A ASN 8   
9  1 Y 1 A SER 8   ? A SER 9   
10 1 Y 1 A LEU 9   ? A LEU 10  
11 1 Y 1 A ALA 10  ? A ALA 11  
12 1 Y 1 A HIS 11  ? A HIS 12  
13 1 Y 1 A LEU 12  ? A LEU 13  
14 1 Y 1 A ARG 13  ? A ARG 14  
15 1 Y 1 A ALA 14  ? A ALA 15  
16 1 Y 1 A ALA 15  ? A ALA 16  
17 1 Y 1 A PRO 16  ? A PRO 17  
18 1 Y 1 A CYS 17  ? A CYS 18  
19 1 Y 1 A ASN 18  ? A ASN 19  
20 1 Y 1 A ASP 19  ? A ASP 20  
21 1 Y 1 A LEU 20  ? A LEU 21  
22 1 Y 1 A HIS 21  ? A HIS 22  
23 1 Y 1 A ALA 22  ? A ALA 23  
24 1 Y 1 A THR 23  ? A THR 24  
25 1 Y 1 A LYS 24  ? A LYS 25  
26 1 Y 1 A LEU 25  ? A LEU 26  
27 1 Y 1 A ALA 26  ? A ALA 27  
28 1 Y 1 A PRO 27  ? A PRO 28  
29 1 Y 1 A GLY 28  ? A GLY 29  
30 1 Y 1 A LYS 29  ? A LYS 30  
31 1 Y 1 A GLU 30  ? A GLU 31  
32 1 Y 1 A LYS 31  ? A LYS 32  
33 1 Y 1 A GLU 32  ? A GLU 33  
34 1 Y 1 A SER 306 ? A SER 307 
35 1 Y 1 A LEU 307 ? A LEU 308 
36 1 Y 1 A SER 308 ? A SER 309 
37 1 Y 1 A PRO 309 ? A PRO 310 
38 1 Y 1 A GLY 310 ? A GLY 311 
39 1 Y 1 A PRO 311 ? A PRO 312 
40 1 Y 1 A SER 312 ? A SER 313 
41 1 Y 1 B ALA 1   ? B ALA 1   
42 1 Y 1 B PRO 11  ? B PRO 11  
43 1 Y 1 B PRO 12  ? B PRO 12  
44 1 Y 1 B THR 13  ? B THR 13  
45 1 Y 1 B ALA 14  ? B ALA 14  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
GOL C1   C N N 137 
GOL O1   O N N 138 
GOL C2   C N N 139 
GOL O2   O N N 140 
GOL C3   C N N 141 
GOL O3   O N N 142 
GOL H11  H N N 143 
GOL H12  H N N 144 
GOL HO1  H N N 145 
GOL H2   H N N 146 
GOL HO2  H N N 147 
GOL H31  H N N 148 
GOL H32  H N N 149 
GOL HO3  H N N 150 
HIS N    N N N 151 
HIS CA   C N S 152 
HIS C    C N N 153 
HIS O    O N N 154 
HIS CB   C N N 155 
HIS CG   C Y N 156 
HIS ND1  N Y N 157 
HIS CD2  C Y N 158 
HIS CE1  C Y N 159 
HIS NE2  N Y N 160 
HIS OXT  O N N 161 
HIS H    H N N 162 
HIS H2   H N N 163 
HIS HA   H N N 164 
HIS HB2  H N N 165 
HIS HB3  H N N 166 
HIS HD1  H N N 167 
HIS HD2  H N N 168 
HIS HE1  H N N 169 
HIS HE2  H N N 170 
HIS HXT  H N N 171 
HOH O    O N N 172 
HOH H1   H N N 173 
HOH H2   H N N 174 
ILE N    N N N 175 
ILE CA   C N S 176 
ILE C    C N N 177 
ILE O    O N N 178 
ILE CB   C N S 179 
ILE CG1  C N N 180 
ILE CG2  C N N 181 
ILE CD1  C N N 182 
ILE OXT  O N N 183 
ILE H    H N N 184 
ILE H2   H N N 185 
ILE HA   H N N 186 
ILE HB   H N N 187 
ILE HG12 H N N 188 
ILE HG13 H N N 189 
ILE HG21 H N N 190 
ILE HG22 H N N 191 
ILE HG23 H N N 192 
ILE HD11 H N N 193 
ILE HD12 H N N 194 
ILE HD13 H N N 195 
ILE HXT  H N N 196 
LEU N    N N N 197 
LEU CA   C N S 198 
LEU C    C N N 199 
LEU O    O N N 200 
LEU CB   C N N 201 
LEU CG   C N N 202 
LEU CD1  C N N 203 
LEU CD2  C N N 204 
LEU OXT  O N N 205 
LEU H    H N N 206 
LEU H2   H N N 207 
LEU HA   H N N 208 
LEU HB2  H N N 209 
LEU HB3  H N N 210 
LEU HG   H N N 211 
LEU HD11 H N N 212 
LEU HD12 H N N 213 
LEU HD13 H N N 214 
LEU HD21 H N N 215 
LEU HD22 H N N 216 
LEU HD23 H N N 217 
LEU HXT  H N N 218 
LYS N    N N N 219 
LYS CA   C N S 220 
LYS C    C N N 221 
LYS O    O N N 222 
LYS CB   C N N 223 
LYS CG   C N N 224 
LYS CD   C N N 225 
LYS CE   C N N 226 
LYS NZ   N N N 227 
LYS OXT  O N N 228 
LYS H    H N N 229 
LYS H2   H N N 230 
LYS HA   H N N 231 
LYS HB2  H N N 232 
LYS HB3  H N N 233 
LYS HG2  H N N 234 
LYS HG3  H N N 235 
LYS HD2  H N N 236 
LYS HD3  H N N 237 
LYS HE2  H N N 238 
LYS HE3  H N N 239 
LYS HZ1  H N N 240 
LYS HZ2  H N N 241 
LYS HZ3  H N N 242 
LYS HXT  H N N 243 
MET N    N N N 244 
MET CA   C N S 245 
MET C    C N N 246 
MET O    O N N 247 
MET CB   C N N 248 
MET CG   C N N 249 
MET SD   S N N 250 
MET CE   C N N 251 
MET OXT  O N N 252 
MET H    H N N 253 
MET H2   H N N 254 
MET HA   H N N 255 
MET HB2  H N N 256 
MET HB3  H N N 257 
MET HG2  H N N 258 
MET HG3  H N N 259 
MET HE1  H N N 260 
MET HE2  H N N 261 
MET HE3  H N N 262 
MET HXT  H N N 263 
PHE N    N N N 264 
PHE CA   C N S 265 
PHE C    C N N 266 
PHE O    O N N 267 
PHE CB   C N N 268 
PHE CG   C Y N 269 
PHE CD1  C Y N 270 
PHE CD2  C Y N 271 
PHE CE1  C Y N 272 
PHE CE2  C Y N 273 
PHE CZ   C Y N 274 
PHE OXT  O N N 275 
PHE H    H N N 276 
PHE H2   H N N 277 
PHE HA   H N N 278 
PHE HB2  H N N 279 
PHE HB3  H N N 280 
PHE HD1  H N N 281 
PHE HD2  H N N 282 
PHE HE1  H N N 283 
PHE HE2  H N N 284 
PHE HZ   H N N 285 
PHE HXT  H N N 286 
PRO N    N N N 287 
PRO CA   C N S 288 
PRO C    C N N 289 
PRO O    O N N 290 
PRO CB   C N N 291 
PRO CG   C N N 292 
PRO CD   C N N 293 
PRO OXT  O N N 294 
PRO H    H N N 295 
PRO HA   H N N 296 
PRO HB2  H N N 297 
PRO HB3  H N N 298 
PRO HG2  H N N 299 
PRO HG3  H N N 300 
PRO HD2  H N N 301 
PRO HD3  H N N 302 
PRO HXT  H N N 303 
SEP N    N N N 304 
SEP CA   C N S 305 
SEP CB   C N N 306 
SEP OG   O N N 307 
SEP C    C N N 308 
SEP O    O N N 309 
SEP OXT  O N N 310 
SEP P    P N N 311 
SEP O1P  O N N 312 
SEP O2P  O N N 313 
SEP O3P  O N N 314 
SEP H    H N N 315 
SEP H2   H N N 316 
SEP HA   H N N 317 
SEP HB2  H N N 318 
SEP HB3  H N N 319 
SEP HXT  H N N 320 
SEP HOP2 H N N 321 
SEP HOP3 H N N 322 
SER N    N N N 323 
SER CA   C N S 324 
SER C    C N N 325 
SER O    O N N 326 
SER CB   C N N 327 
SER OG   O N N 328 
SER OXT  O N N 329 
SER H    H N N 330 
SER H2   H N N 331 
SER HA   H N N 332 
SER HB2  H N N 333 
SER HB3  H N N 334 
SER HG   H N N 335 
SER HXT  H N N 336 
THR N    N N N 337 
THR CA   C N S 338 
THR C    C N N 339 
THR O    O N N 340 
THR CB   C N R 341 
THR OG1  O N N 342 
THR CG2  C N N 343 
THR OXT  O N N 344 
THR H    H N N 345 
THR H2   H N N 346 
THR HA   H N N 347 
THR HB   H N N 348 
THR HG1  H N N 349 
THR HG21 H N N 350 
THR HG22 H N N 351 
THR HG23 H N N 352 
THR HXT  H N N 353 
TRP N    N N N 354 
TRP CA   C N S 355 
TRP C    C N N 356 
TRP O    O N N 357 
TRP CB   C N N 358 
TRP CG   C Y N 359 
TRP CD1  C Y N 360 
TRP CD2  C Y N 361 
TRP NE1  N Y N 362 
TRP CE2  C Y N 363 
TRP CE3  C Y N 364 
TRP CZ2  C Y N 365 
TRP CZ3  C Y N 366 
TRP CH2  C Y N 367 
TRP OXT  O N N 368 
TRP H    H N N 369 
TRP H2   H N N 370 
TRP HA   H N N 371 
TRP HB2  H N N 372 
TRP HB3  H N N 373 
TRP HD1  H N N 374 
TRP HE1  H N N 375 
TRP HE3  H N N 376 
TRP HZ2  H N N 377 
TRP HZ3  H N N 378 
TRP HH2  H N N 379 
TRP HXT  H N N 380 
TYR N    N N N 381 
TYR CA   C N S 382 
TYR C    C N N 383 
TYR O    O N N 384 
TYR CB   C N N 385 
TYR CG   C Y N 386 
TYR CD1  C Y N 387 
TYR CD2  C Y N 388 
TYR CE1  C Y N 389 
TYR CE2  C Y N 390 
TYR CZ   C Y N 391 
TYR OH   O N N 392 
TYR OXT  O N N 393 
TYR H    H N N 394 
TYR H2   H N N 395 
TYR HA   H N N 396 
TYR HB2  H N N 397 
TYR HB3  H N N 398 
TYR HD1  H N N 399 
TYR HD2  H N N 400 
TYR HE1  H N N 401 
TYR HE2  H N N 402 
TYR HH   H N N 403 
TYR HXT  H N N 404 
VAL N    N N N 405 
VAL CA   C N S 406 
VAL C    C N N 407 
VAL O    O N N 408 
VAL CB   C N N 409 
VAL CG1  C N N 410 
VAL CG2  C N N 411 
VAL OXT  O N N 412 
VAL H    H N N 413 
VAL H2   H N N 414 
VAL HA   H N N 415 
VAL HB   H N N 416 
VAL HG11 H N N 417 
VAL HG12 H N N 418 
VAL HG13 H N N 419 
VAL HG21 H N N 420 
VAL HG22 H N N 421 
VAL HG23 H N N 422 
VAL HXT  H N N 423 
XJL N2   N Y N 424 
XJL C2   C Y N 425 
XJL N1   N N N 426 
XJL C4   C Y N 427 
XJL C5   C Y N 428 
XJL C14  C Y N 429 
XJL C7   C Y N 430 
XJL C10  C Y N 431 
XJL C15  C Y N 432 
XJL C8   C Y N 433 
XJL C11  C Y N 434 
XJL C13  C Y N 435 
XJL C1   C Y N 436 
XJL C9   C Y N 437 
XJL C3   C Y N 438 
XJL C12  C Y N 439 
XJL C6   C Y N 440 
XJL O1   O N N 441 
XJL N    N Y N 442 
XJL C    C N N 443 
XJL O    O N N 444 
XJL H1   H N N 445 
XJL H8   H N N 446 
XJL H7   H N N 447 
XJL H3   H N N 448 
XJL H4   H N N 449 
XJL H11  H N N 450 
XJL H6   H N N 451 
XJL H12  H N N 452 
XJL H10  H N N 453 
XJL H5   H N N 454 
XJL H2   H N N 455 
XJL H9   H N N 456 
XJL H    H N N 457 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SEP N   CA   sing N N 290 
SEP N   H    sing N N 291 
SEP N   H2   sing N N 292 
SEP CA  CB   sing N N 293 
SEP CA  C    sing N N 294 
SEP CA  HA   sing N N 295 
SEP CB  OG   sing N N 296 
SEP CB  HB2  sing N N 297 
SEP CB  HB3  sing N N 298 
SEP OG  P    sing N N 299 
SEP C   O    doub N N 300 
SEP C   OXT  sing N N 301 
SEP OXT HXT  sing N N 302 
SEP P   O1P  doub N N 303 
SEP P   O2P  sing N N 304 
SEP P   O3P  sing N N 305 
SEP O2P HOP2 sing N N 306 
SEP O3P HOP3 sing N N 307 
SER N   CA   sing N N 308 
SER N   H    sing N N 309 
SER N   H2   sing N N 310 
SER CA  C    sing N N 311 
SER CA  CB   sing N N 312 
SER CA  HA   sing N N 313 
SER C   O    doub N N 314 
SER C   OXT  sing N N 315 
SER CB  OG   sing N N 316 
SER CB  HB2  sing N N 317 
SER CB  HB3  sing N N 318 
SER OG  HG   sing N N 319 
SER OXT HXT  sing N N 320 
THR N   CA   sing N N 321 
THR N   H    sing N N 322 
THR N   H2   sing N N 323 
THR CA  C    sing N N 324 
THR CA  CB   sing N N 325 
THR CA  HA   sing N N 326 
THR C   O    doub N N 327 
THR C   OXT  sing N N 328 
THR CB  OG1  sing N N 329 
THR CB  CG2  sing N N 330 
THR CB  HB   sing N N 331 
THR OG1 HG1  sing N N 332 
THR CG2 HG21 sing N N 333 
THR CG2 HG22 sing N N 334 
THR CG2 HG23 sing N N 335 
THR OXT HXT  sing N N 336 
TRP N   CA   sing N N 337 
TRP N   H    sing N N 338 
TRP N   H2   sing N N 339 
TRP CA  C    sing N N 340 
TRP CA  CB   sing N N 341 
TRP CA  HA   sing N N 342 
TRP C   O    doub N N 343 
TRP C   OXT  sing N N 344 
TRP CB  CG   sing N N 345 
TRP CB  HB2  sing N N 346 
TRP CB  HB3  sing N N 347 
TRP CG  CD1  doub Y N 348 
TRP CG  CD2  sing Y N 349 
TRP CD1 NE1  sing Y N 350 
TRP CD1 HD1  sing N N 351 
TRP CD2 CE2  doub Y N 352 
TRP CD2 CE3  sing Y N 353 
TRP NE1 CE2  sing Y N 354 
TRP NE1 HE1  sing N N 355 
TRP CE2 CZ2  sing Y N 356 
TRP CE3 CZ3  doub Y N 357 
TRP CE3 HE3  sing N N 358 
TRP CZ2 CH2  doub Y N 359 
TRP CZ2 HZ2  sing N N 360 
TRP CZ3 CH2  sing Y N 361 
TRP CZ3 HZ3  sing N N 362 
TRP CH2 HH2  sing N N 363 
TRP OXT HXT  sing N N 364 
TYR N   CA   sing N N 365 
TYR N   H    sing N N 366 
TYR N   H2   sing N N 367 
TYR CA  C    sing N N 368 
TYR CA  CB   sing N N 369 
TYR CA  HA   sing N N 370 
TYR C   O    doub N N 371 
TYR C   OXT  sing N N 372 
TYR CB  CG   sing N N 373 
TYR CB  HB2  sing N N 374 
TYR CB  HB3  sing N N 375 
TYR CG  CD1  doub Y N 376 
TYR CG  CD2  sing Y N 377 
TYR CD1 CE1  sing Y N 378 
TYR CD1 HD1  sing N N 379 
TYR CD2 CE2  doub Y N 380 
TYR CD2 HD2  sing N N 381 
TYR CE1 CZ   doub Y N 382 
TYR CE1 HE1  sing N N 383 
TYR CE2 CZ   sing Y N 384 
TYR CE2 HE2  sing N N 385 
TYR CZ  OH   sing N N 386 
TYR OH  HH   sing N N 387 
TYR OXT HXT  sing N N 388 
VAL N   CA   sing N N 389 
VAL N   H    sing N N 390 
VAL N   H2   sing N N 391 
VAL CA  C    sing N N 392 
VAL CA  CB   sing N N 393 
VAL CA  HA   sing N N 394 
VAL C   O    doub N N 395 
VAL C   OXT  sing N N 396 
VAL CB  CG1  sing N N 397 
VAL CB  CG2  sing N N 398 
VAL CB  HB   sing N N 399 
VAL CG1 HG11 sing N N 400 
VAL CG1 HG12 sing N N 401 
VAL CG1 HG13 sing N N 402 
VAL CG2 HG21 sing N N 403 
VAL CG2 HG22 sing N N 404 
VAL CG2 HG23 sing N N 405 
VAL OXT HXT  sing N N 406 
XJL C   O    doub N N 407 
XJL O1  C    sing N N 408 
XJL C1  C    sing N N 409 
XJL C1  C2   sing Y N 410 
XJL C2  C3   doub Y N 411 
XJL C4  C1   doub Y N 412 
XJL C5  C4   sing Y N 413 
XJL C6  C5   doub Y N 414 
XJL C3  C6   sing Y N 415 
XJL N   C6   sing N N 416 
XJL N   C7   sing Y N 417 
XJL C8  C7   sing N N 418 
XJL C8  C9   doub Y N 419 
XJL C9  C10  sing Y N 420 
XJL C10 C11  doub Y N 421 
XJL N1  C11  sing N N 422 
XJL C11 C12  sing Y N 423 
XJL C12 C13  doub Y N 424 
XJL C13 C8   sing Y N 425 
XJL C7  C14  doub Y N 426 
XJL C14 C15  sing Y N 427 
XJL C15 N2   doub Y N 428 
XJL N2  N    sing Y N 429 
XJL C2  H1   sing N N 430 
XJL N1  H8   sing N N 431 
XJL N1  H7   sing N N 432 
XJL C4  H3   sing N N 433 
XJL C5  H4   sing N N 434 
XJL C14 H11  sing N N 435 
XJL C10 H6   sing N N 436 
XJL C15 H12  sing N N 437 
XJL C13 H10  sing N N 438 
XJL C9  H5   sing N N 439 
XJL C3  H2   sing N N 440 
XJL C12 H9   sing N N 441 
XJL O1  H    sing N N 442 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5NDT 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 65' 
_space_group.name_Hall        'P 65' 
_space_group.IT_number        170 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8R25 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010168 
_atom_sites.fract_transf_matrix[1][2]   0.005870 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011740 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012464 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . PRO A 1 34  ? -80.63703 -111.16291 -17.33429 1.000 110.40566 ? 33  PRO A N   1 
ATOM   2    C CA  . PRO A 1 34  ? -81.67784 -111.44078 -16.33797 1.000 108.00609 ? 33  PRO A CA  1 
ATOM   3    C C   . PRO A 1 34  ? -81.24165 -112.47397 -15.30158 1.000 101.82425 ? 33  PRO A C   1 
ATOM   4    O O   . PRO A 1 34  ? -81.58644 -113.64973 -15.41868 1.000 99.94225  ? 33  PRO A O   1 
ATOM   5    C CB  . PRO A 1 34  ? -82.83976 -111.97299 -17.18402 1.000 109.28371 ? 33  PRO A CB  1 
ATOM   6    C CG  . PRO A 1 34  ? -82.19597 -112.50692 -18.41892 1.000 108.62150 ? 33  PRO A CG  1 
ATOM   7    C CD  . PRO A 1 34  ? -81.02977 -111.60386 -18.68373 1.000 110.56514 ? 33  PRO A CD  1 
ATOM   8    N N   . LEU A 1 35  ? -80.48670 -112.03081 -14.29445 1.000 99.95101  ? 34  LEU A N   1 
ATOM   9    C CA  . LEU A 1 35  ? -80.03674 -112.94031 -13.24719 1.000 95.10069  ? 34  LEU A CA  1 
ATOM   10   C C   . LEU A 1 35  ? -81.12749 -113.21693 -12.22036 1.000 94.99406  ? 34  LEU A C   1 
ATOM   11   O O   . LEU A 1 35  ? -81.12836 -114.28411 -11.59685 1.000 89.33169  ? 34  LEU A O   1 
ATOM   12   C CB  . LEU A 1 35  ? -78.79780 -112.37241 -12.55244 1.000 91.02659  ? 34  LEU A CB  1 
ATOM   13   N N   . GLU A 1 36  ? -82.05854 -112.27899 -12.03143 1.000 98.14895  ? 35  GLU A N   1 
ATOM   14   C CA  . GLU A 1 36  ? -83.11218 -112.47547 -11.04210 1.000 95.75677  ? 35  GLU A CA  1 
ATOM   15   C C   . GLU A 1 36  ? -84.15856 -113.47337 -11.52177 1.000 95.98787  ? 35  GLU A C   1 
ATOM   16   O O   . GLU A 1 36  ? -84.78882 -114.15035 -10.70091 1.000 96.27242  ? 35  GLU A O   1 
ATOM   17   C CB  . GLU A 1 36  ? -83.76970 -111.13699 -10.70467 1.000 96.84654  ? 35  GLU A CB  1 
ATOM   18   N N   . SER A 1 37  ? -84.35303 -113.58419 -12.83547 1.000 95.12338  ? 36  SER A N   1 
ATOM   19   C CA  . SER A 1 37  ? -85.36498 -114.46663 -13.40056 1.000 94.62332  ? 36  SER A CA  1 
ATOM   20   C C   . SER A 1 37  ? -84.83094 -115.84660 -13.75836 1.000 90.96630  ? 36  SER A C   1 
ATOM   21   O O   . SER A 1 37  ? -85.62985 -116.75990 -13.99143 1.000 93.83677  ? 36  SER A O   1 
ATOM   22   C CB  . SER A 1 37  ? -85.98146 -113.82813 -14.65103 1.000 95.89519  ? 36  SER A CB  1 
ATOM   23   N N   . GLN A 1 38  ? -83.51121 -116.02403 -13.80468 1.000 90.13652  ? 37  GLN A N   1 
ATOM   24   C CA  . GLN A 1 38  ? -82.92286 -117.29028 -14.21810 1.000 83.77387  ? 37  GLN A CA  1 
ATOM   25   C C   . GLN A 1 38  ? -82.55482 -118.19830 -13.05144 1.000 79.80829  ? 37  GLN A C   1 
ATOM   26   O O   . GLN A 1 38  ? -82.40873 -119.40905 -13.25296 1.000 78.32663  ? 37  GLN A O   1 
ATOM   27   C CB  . GLN A 1 38  ? -81.67739 -117.03292 -15.07709 1.000 83.10338  ? 37  GLN A CB  1 
ATOM   28   C CG  . GLN A 1 38  ? -81.22876 -118.21891 -15.91532 1.000 82.60775  ? 37  GLN A CG  1 
ATOM   29   C CD  . GLN A 1 38  ? -80.13168 -117.85253 -16.89727 1.000 82.88636  ? 37  GLN A CD  1 
ATOM   30   O OE1 . GLN A 1 38  ? -79.47356 -118.72432 -17.46622 1.000 82.79626  ? 37  GLN A OE1 1 
ATOM   31   N NE2 . GLN A 1 38  ? -79.93244 -116.55511 -17.10404 1.000 81.53292  ? 37  GLN A NE2 1 
ATOM   32   N N   . TYR A 1 39  ? -82.41256 -117.65610 -11.84419 1.000 81.32616  ? 38  TYR A N   1 
ATOM   33   C CA  . TYR A 1 39  ? -82.03505 -118.44197 -10.67915 1.000 76.51712  ? 38  TYR A CA  1 
ATOM   34   C C   . TYR A 1 39  ? -82.92169 -118.08012 -9.49691  1.000 77.40869  ? 38  TYR A C   1 
ATOM   35   O O   . TYR A 1 39  ? -83.33394 -116.92806 -9.33681  1.000 79.30166  ? 38  TYR A O   1 
ATOM   36   C CB  . TYR A 1 39  ? -80.56099 -118.22581 -10.30446 1.000 72.29096  ? 38  TYR A CB  1 
ATOM   37   C CG  . TYR A 1 39  ? -79.59397 -118.58800 -11.40618 1.000 70.98373  ? 38  TYR A CG  1 
ATOM   38   C CD1 . TYR A 1 39  ? -79.12329 -119.88647 -11.54345 1.000 67.30326  ? 38  TYR A CD1 1 
ATOM   39   C CD2 . TYR A 1 39  ? -79.15284 -117.63187 -12.31101 1.000 73.29973  ? 38  TYR A CD2 1 
ATOM   40   C CE1 . TYR A 1 39  ? -78.24189 -120.22419 -12.55209 1.000 68.18013  ? 38  TYR A CE1 1 
ATOM   41   C CE2 . TYR A 1 39  ? -78.27056 -117.95977 -13.32323 1.000 71.19730  ? 38  TYR A CE2 1 
ATOM   42   C CZ  . TYR A 1 39  ? -77.81819 -119.25744 -13.43903 1.000 69.84686  ? 38  TYR A CZ  1 
ATOM   43   O OH  . TYR A 1 39  ? -76.94043 -119.58909 -14.44602 1.000 71.31457  ? 38  TYR A OH  1 
ATOM   44   N N   . GLN A 1 40  ? -83.21147 -119.08181 -8.66889  1.000 75.11139  ? 39  GLN A N   1 
ATOM   45   C CA  . GLN A 1 40  ? -83.95190 -118.89479 -7.42573  1.000 72.16433  ? 39  GLN A CA  1 
ATOM   46   C C   . GLN A 1 40  ? -82.94021 -118.85148 -6.28616  1.000 71.15764  ? 39  GLN A C   1 
ATOM   47   O O   . GLN A 1 40  ? -82.24912 -119.84089 -6.02344  1.000 71.57938  ? 39  GLN A O   1 
ATOM   48   C CB  . GLN A 1 40  ? -84.97179 -120.01342 -7.22417  1.000 72.11669  ? 39  GLN A CB  1 
ATOM   49   C CG  . GLN A 1 40  ? -85.85449 -119.84601 -5.99862  1.000 71.11827  ? 39  GLN A CG  1 
ATOM   50   N N   . VAL A 1 41  ? -82.84467 -117.70444 -5.62204  1.000 69.94848  ? 40  VAL A N   1 
ATOM   51   C CA  . VAL A 1 41  ? -81.83231 -117.49949 -4.59146  1.000 69.28409  ? 40  VAL A CA  1 
ATOM   52   C C   . VAL A 1 41  ? -82.34594 -118.03968 -3.26352  1.000 67.96058  ? 40  VAL A C   1 
ATOM   53   O O   . VAL A 1 41  ? -83.43168 -117.66729 -2.80294  1.000 70.86437  ? 40  VAL A O   1 
ATOM   54   C CB  . VAL A 1 41  ? -81.46070 -116.01189 -4.48089  1.000 65.69639  ? 40  VAL A CB  1 
ATOM   55   C CG1 . VAL A 1 41  ? -80.38619 -115.81084 -3.42299  1.000 63.82653  ? 40  VAL A CG1 1 
ATOM   56   C CG2 . VAL A 1 41  ? -80.99556 -115.48046 -5.82790  1.000 64.71356  ? 40  VAL A CG2 1 
ATOM   57   N N   . GLY A 1 42  ? -81.56107 -118.91617 -2.64186  1.000 66.65187  ? 41  GLY A N   1 
ATOM   58   C CA  . GLY A 1 42  ? -81.91175 -119.48741 -1.36449  1.000 65.58143  ? 41  GLY A CA  1 
ATOM   59   C C   . GLY A 1 42  ? -81.16040 -118.84041 -0.21916  1.000 66.58923  ? 41  GLY A C   1 
ATOM   60   O O   . GLY A 1 42  ? -80.86615 -117.64086 -0.23538  1.000 66.82865  ? 41  GLY A O   1 
ATOM   61   N N   . PRO A 1 43  ? -80.83166 -119.62772 0.79955   1.000 67.07813  ? 42  PRO A N   1 
ATOM   62   C CA  . PRO A 1 43  ? -80.16617 -119.07462 1.98116   1.000 65.55689  ? 42  PRO A CA  1 
ATOM   63   C C   . PRO A 1 43  ? -78.69305 -118.78645 1.72885   1.000 62.41405  ? 42  PRO A C   1 
ATOM   64   O O   . PRO A 1 43  ? -78.07626 -119.29111 0.78924   1.000 60.33911  ? 42  PRO A O   1 
ATOM   65   C CB  . PRO A 1 43  ? -80.33513 -120.18157 3.02688   1.000 63.31980  ? 42  PRO A CB  1 
ATOM   66   C CG  . PRO A 1 43  ? -80.38523 -121.43389 2.22049   1.000 69.62933  ? 42  PRO A CG  1 
ATOM   67   C CD  . PRO A 1 43  ? -81.08540 -121.07371 0.93164   1.000 68.70467  ? 42  PRO A CD  1 
ATOM   68   N N   . LEU A 1 44  ? -78.13498 -117.95563 2.60496   1.000 61.30539  ? 43  LEU A N   1 
ATOM   69   C CA  . LEU A 1 44  ? -76.71837 -117.62242 2.54504   1.000 61.04266  ? 43  LEU A CA  1 
ATOM   70   C C   . LEU A 1 44  ? -75.88911 -118.81489 3.00830   1.000 62.61836  ? 43  LEU A C   1 
ATOM   71   O O   . LEU A 1 44  ? -76.05932 -119.29876 4.13166   1.000 66.08238  ? 43  LEU A O   1 
ATOM   72   C CB  . LEU A 1 44  ? -76.43575 -116.39809 3.41145   1.000 62.11066  ? 43  LEU A CB  1 
ATOM   73   C CG  . LEU A 1 44  ? -75.00693 -115.85676 3.43567   1.000 62.01644  ? 43  LEU A CG  1 
ATOM   74   C CD1 . LEU A 1 44  ? -74.61912 -115.29220 2.07512   1.000 61.43223  ? 43  LEU A CD1 1 
ATOM   75   C CD2 . LEU A 1 44  ? -74.86433 -114.80009 4.51903   1.000 63.16786  ? 43  LEU A CD2 1 
ATOM   76   N N   . LEU A 1 45  ? -74.99522 -119.29494 2.14247   1.000 60.18910  ? 44  LEU A N   1 
ATOM   77   C CA  . LEU A 1 45  ? -74.15546 -120.43247 2.50155   1.000 60.59488  ? 44  LEU A CA  1 
ATOM   78   C C   . LEU A 1 45  ? -72.93249 -120.01331 3.30435   1.000 62.59358  ? 44  LEU A C   1 
ATOM   79   O O   . LEU A 1 45  ? -72.46875 -120.77398 4.16139   1.000 65.82812  ? 44  LEU A O   1 
ATOM   80   C CB  . LEU A 1 45  ? -73.71708 -121.18458 1.24459   1.000 61.17032  ? 44  LEU A CB  1 
ATOM   81   C CG  . LEU A 1 45  ? -74.82722 -121.88097 0.45927   1.000 59.15624  ? 44  LEU A CG  1 
ATOM   82   C CD1 . LEU A 1 45  ? -74.24706 -122.63164 -0.72328  1.000 59.76627  ? 44  LEU A CD1 1 
ATOM   83   C CD2 . LEU A 1 45  ? -75.60945 -122.81799 1.36475   1.000 64.72071  ? 44  LEU A CD2 1 
ATOM   84   N N   . GLY A 1 46  ? -72.40039 -118.82769 3.04382   1.000 68.61288  ? 45  GLY A N   1 
ATOM   85   C CA  . GLY A 1 46  ? -71.23751 -118.35262 3.76590   1.000 63.80682  ? 45  GLY A CA  1 
ATOM   86   C C   . GLY A 1 46  ? -70.75445 -117.04711 3.18178   1.000 67.68228  ? 45  GLY A C   1 
ATOM   87   O O   . GLY A 1 46  ? -71.19085 -116.61073 2.11112   1.000 59.83921  ? 45  GLY A O   1 
ATOM   88   N N   . SER A 1 47  ? -69.83667 -116.42028 3.91407   1.000 66.50895  ? 46  SER A N   1 
ATOM   89   C CA  . SER A 1 47  ? -69.26030 -115.15452 3.48956   1.000 67.85017  ? 46  SER A CA  1 
ATOM   90   C C   . SER A 1 47  ? -67.85535 -115.03406 4.05837   1.000 72.43213  ? 46  SER A C   1 
ATOM   91   O O   . SER A 1 47  ? -67.46170 -115.77194 4.96507   1.000 75.29878  ? 46  SER A O   1 
ATOM   92   C CB  . SER A 1 47  ? -70.12562 -113.96683 3.92392   1.000 66.96007  ? 46  SER A CB  1 
ATOM   93   O OG  . SER A 1 47  ? -70.20594 -113.88510 5.33603   1.000 71.56840  ? 46  SER A OG  1 
ATOM   94   N N   . GLY A 1 48  ? -67.10781 -114.09173 3.51922   1.000 74.10371  ? 47  GLY A N   1 
ATOM   95   C CA  . GLY A 1 48  ? -65.75330 -113.83844 3.96133   1.000 80.35913  ? 47  GLY A CA  1 
ATOM   96   C C   . GLY A 1 48  ? -64.90923 -113.33183 2.79830   1.000 81.16150  ? 47  GLY A C   1 
ATOM   97   O O   . GLY A 1 48  ? -65.39104 -112.56397 1.96393   1.000 79.49885  ? 47  GLY A O   1 
ATOM   98   N N   . GLY A 1 49  ? -63.65229 -113.78198 2.76485   1.000 83.73504  ? 48  GLY A N   1 
ATOM   99   C CA  . GLY A 1 49  ? -62.76435 -113.39726 1.67983   1.000 86.97088  ? 48  GLY A CA  1 
ATOM   100  C C   . GLY A 1 49  ? -63.26767 -113.81733 0.31366   1.000 84.48744  ? 48  GLY A C   1 
ATOM   101  O O   . GLY A 1 49  ? -62.90789 -113.21102 -0.69850  1.000 90.71484  ? 48  GLY A O   1 
ATOM   102  N N   . PHE A 1 50  ? -64.10819 -114.84867 0.26147   1.000 89.91325  ? 49  PHE A N   1 
ATOM   103  C CA  . PHE A 1 50  ? -64.67359 -115.30019 -1.00373  1.000 82.97960  ? 49  PHE A CA  1 
ATOM   104  C C   . PHE A 1 50  ? -66.01393 -114.61093 -1.25428  1.000 87.47784  ? 49  PHE A C   1 
ATOM   105  O O   . PHE A 1 50  ? -66.92129 -115.19147 -1.86427  1.000 89.98847  ? 49  PHE A O   1 
ATOM   106  C CB  . PHE A 1 50  ? -64.83230 -116.81797 -1.01518  1.000 77.09281  ? 49  PHE A CB  1 
ATOM   107  N N   . GLY A 1 51  ? -66.14230 -113.36700 -0.78615  1.000 77.54445  ? 50  GLY A N   1 
ATOM   108  C CA  . GLY A 1 51  ? -67.36822 -112.61599 -0.99697  1.000 68.34490  ? 50  GLY A CA  1 
ATOM   109  C C   . GLY A 1 51  ? -68.51020 -113.16574 -0.16247  1.000 68.73825  ? 50  GLY A C   1 
ATOM   110  O O   . GLY A 1 51  ? -68.34712 -113.53529 1.00641   1.000 63.78386  ? 50  GLY A O   1 
ATOM   111  N N   . SER A 1 52  ? -69.68956 -113.22098 -0.77537  1.000 62.13511  ? 51  SER A N   1 
ATOM   112  C CA  . SER A 1 52  ? -70.88289 -113.77585 -0.15293  1.000 53.54753  ? 51  SER A CA  1 
ATOM   113  C C   . SER A 1 52  ? -71.46180 -114.82114 -1.09075  1.000 53.91418  ? 51  SER A C   1 
ATOM   114  O O   . SER A 1 52  ? -71.67335 -114.54227 -2.27530  1.000 51.74263  ? 51  SER A O   1 
ATOM   115  C CB  . SER A 1 52  ? -71.91507 -112.68213 0.13983   1.000 51.68253  ? 51  SER A CB  1 
ATOM   116  O OG  . SER A 1 52  ? -71.33038 -111.61108 0.86257   1.000 51.04620  ? 51  SER A OG  1 
ATOM   117  N N   . VAL A 1 53  ? -71.70621 -116.02008 -0.56940  1.000 48.54296  ? 52  VAL A N   1 
ATOM   118  C CA  . VAL A 1 53  ? -72.14285 -117.15538 -1.37429  1.000 48.89499  ? 52  VAL A CA  1 
ATOM   119  C C   . VAL A 1 53  ? -73.53003 -117.57119 -0.90881  1.000 52.75670  ? 52  VAL A C   1 
ATOM   120  O O   . VAL A 1 53  ? -73.72881 -117.87773 0.27337   1.000 57.16501  ? 52  VAL A O   1 
ATOM   121  C CB  . VAL A 1 53  ? -71.15835 -118.33193 -1.28420  1.000 53.50768  ? 52  VAL A CB  1 
ATOM   122  C CG1 . VAL A 1 53  ? -71.59622 -119.46118 -2.20400  1.000 48.86214  ? 52  VAL A CG1 1 
ATOM   123  C CG2 . VAL A 1 53  ? -69.74812 -117.86933 -1.62965  1.000 52.28200  ? 52  VAL A CG2 1 
ATOM   124  N N   . TYR A 1 54  ? -74.48173 -117.59046 -1.83833  1.000 50.39799  ? 53  TYR A N   1 
ATOM   125  C CA  . TYR A 1 54  ? -75.85627 -117.98229 -1.56642  1.000 53.55640  ? 53  TYR A CA  1 
ATOM   126  C C   . TYR A 1 54  ? -76.15911 -119.31430 -2.23523  1.000 58.95540  ? 53  TYR A C   1 
ATOM   127  O O   . TYR A 1 54  ? -75.68503 -119.58594 -3.34378  1.000 55.32002  ? 53  TYR A O   1 
ATOM   128  C CB  . TYR A 1 54  ? -76.84881 -116.93170 -2.07551  1.000 52.13405  ? 53  TYR A CB  1 
ATOM   129  C CG  . TYR A 1 54  ? -76.74937 -115.58614 -1.39911  1.000 51.28905  ? 53  TYR A CG  1 
ATOM   130  C CD1 . TYR A 1 54  ? -75.80137 -114.65515 -1.80347  1.000 46.59428  ? 53  TYR A CD1 1 
ATOM   131  C CD2 . TYR A 1 54  ? -77.61285 -115.23985 -0.36567  1.000 52.36403  ? 53  TYR A CD2 1 
ATOM   132  C CE1 . TYR A 1 54  ? -75.70658 -113.42309 -1.19426  1.000 47.78159  ? 53  TYR A CE1 1 
ATOM   133  C CE2 . TYR A 1 54  ? -77.52772 -114.00574 0.25126   1.000 47.67125  ? 53  TYR A CE2 1 
ATOM   134  C CZ  . TYR A 1 54  ? -76.57240 -113.10142 -0.16750  1.000 50.19594  ? 53  TYR A CZ  1 
ATOM   135  O OH  . TYR A 1 54  ? -76.47422 -111.87030 0.43589   1.000 47.78887  ? 53  TYR A OH  1 
ATOM   136  N N   . SER A 1 55  ? -76.95516 -120.13890 -1.56138  1.000 59.43886  ? 54  SER A N   1 
ATOM   137  C CA  . SER A 1 55  ? -77.49415 -121.32618 -2.20336  1.000 61.50891  ? 54  SER A CA  1 
ATOM   138  C C   . SER A 1 55  ? -78.49231 -120.91876 -3.27990  1.000 61.32160  ? 54  SER A C   1 
ATOM   139  O O   . SER A 1 55  ? -79.20552 -119.92102 -3.15079  1.000 65.02476  ? 54  SER A O   1 
ATOM   140  C CB  . SER A 1 55  ? -78.16412 -122.23776 -1.17558  1.000 63.03584  ? 54  SER A CB  1 
ATOM   141  O OG  . SER A 1 55  ? -78.66155 -123.41653 -1.78551  1.000 68.14093  ? 54  SER A OG  1 
ATOM   142  N N   . GLY A 1 56  ? -78.53249 -121.69379 -4.35831  1.000 61.87276  ? 55  GLY A N   1 
ATOM   143  C CA  . GLY A 1 56  ? -79.39431 -121.35451 -5.47351  1.000 60.62778  ? 55  GLY A CA  1 
ATOM   144  C C   . GLY A 1 56  ? -79.81251 -122.57908 -6.25412  1.000 64.44269  ? 55  GLY A C   1 
ATOM   145  O O   . GLY A 1 56  ? -79.22463 -123.65867 -6.13186  1.000 67.90244  ? 55  GLY A O   1 
ATOM   146  N N   . ILE A 1 57  ? -80.85370 -122.39299 -7.05965  1.000 64.92554  ? 56  ILE A N   1 
ATOM   147  C CA  . ILE A 1 57  ? -81.36704 -123.42378 -7.95255  1.000 69.92486  ? 56  ILE A CA  1 
ATOM   148  C C   . ILE A 1 57  ? -81.63861 -122.77703 -9.30146  1.000 72.59773  ? 56  ILE A C   1 
ATOM   149  O O   . ILE A 1 57  ? -82.35757 -121.77561 -9.37989  1.000 77.48514  ? 56  ILE A O   1 
ATOM   150  C CB  . ILE A 1 57  ? -82.64795 -124.08379 -7.40368  1.000 72.55436  ? 56  ILE A CB  1 
ATOM   151  C CG1 . ILE A 1 57  ? -82.35888 -124.81877 -6.09222  1.000 66.95615  ? 56  ILE A CG1 1 
ATOM   152  N N   . ARG A 1 58  ? -81.05597 -123.33522 -10.35850 1.000 73.07139  ? 57  ARG A N   1 
ATOM   153  C CA  . ARG A 1 58  ? -81.30596 -122.83049 -11.70212 1.000 76.04531  ? 57  ARG A CA  1 
ATOM   154  C C   . ARG A 1 58  ? -82.70771 -123.23574 -12.14130 1.000 82.92830  ? 57  ARG A C   1 
ATOM   155  O O   . ARG A 1 58  ? -83.02887 -124.42711 -12.18898 1.000 84.41073  ? 57  ARG A O   1 
ATOM   156  C CB  . ARG A 1 58  ? -80.25488 -123.36286 -12.67228 1.000 76.17773  ? 57  ARG A CB  1 
ATOM   157  C CG  . ARG A 1 58  ? -80.38530 -122.82612 -14.08797 1.000 76.33933  ? 57  ARG A CG  1 
ATOM   158  C CD  . ARG A 1 58  ? -79.16095 -123.17084 -14.92038 1.000 77.28096  ? 57  ARG A CD  1 
ATOM   159  N NE  . ARG A 1 58  ? -78.91835 -124.60756 -14.97115 1.000 78.20438  ? 57  ARG A NE  1 
ATOM   160  C CZ  . ARG A 1 58  ? -77.86987 -125.16965 -15.55659 1.000 76.01605  ? 57  ARG A CZ  1 
ATOM   161  N NH1 . ARG A 1 58  ? -76.93701 -124.44228 -16.14878 1.000 72.07517  ? 57  ARG A NH1 1 
ATOM   162  N NH2 . ARG A 1 58  ? -77.75292 -126.49465 -15.54494 1.000 75.36873  ? 57  ARG A NH2 1 
ATOM   163  N N   . VAL A 1 59  ? -83.54322 -122.24339 -12.46064 1.000 84.32275  ? 58  VAL A N   1 
ATOM   164  C CA  . VAL A 1 59  ? -84.94375 -122.51557 -12.77609 1.000 84.75695  ? 58  VAL A CA  1 
ATOM   165  C C   . VAL A 1 59  ? -85.07167 -123.38063 -14.02277 1.000 90.49279  ? 58  VAL A C   1 
ATOM   166  O O   . VAL A 1 59  ? -86.05831 -124.11015 -14.18227 1.000 93.07511  ? 58  VAL A O   1 
ATOM   167  C CB  . VAL A 1 59  ? -85.71980 -121.19254 -12.92881 1.000 80.90233  ? 58  VAL A CB  1 
ATOM   168  N N   . SER A 1 60  ? -84.08090 -123.32810 -14.91707 1.000 91.25437  ? 59  SER A N   1 
ATOM   169  C CA  . SER A 1 60  ? -84.16839 -124.07573 -16.16752 1.000 87.74870  ? 59  SER A CA  1 
ATOM   170  C C   . SER A 1 60  ? -84.16850 -125.58254 -15.93720 1.000 89.31008  ? 59  SER A C   1 
ATOM   171  O O   . SER A 1 60  ? -84.77553 -126.32352 -16.71851 1.000 92.06162  ? 59  SER A O   1 
ATOM   172  C CB  . SER A 1 60  ? -83.01799 -123.68346 -17.09493 1.000 88.20409  ? 59  SER A CB  1 
ATOM   173  N N   . ASP A 1 61  ? -83.50129 -126.05920 -14.87636 1.000 86.28262  ? 60  ASP A N   1 
ATOM   174  C CA  . ASP A 1 61  ? -83.44239 -127.50037 -14.65062 1.000 85.63341  ? 60  ASP A CA  1 
ATOM   175  C C   . ASP A 1 61  ? -83.27843 -127.88260 -13.18048 1.000 88.16098  ? 60  ASP A C   1 
ATOM   176  O O   . ASP A 1 61  ? -82.92951 -129.03520 -12.89730 1.000 88.33099  ? 60  ASP A O   1 
ATOM   177  C CB  . ASP A 1 61  ? -82.29635 -128.12026 -15.46944 1.000 84.29743  ? 60  ASP A CB  1 
ATOM   178  C CG  . ASP A 1 61  ? -80.97073 -127.41457 -15.24938 1.000 84.45292  ? 60  ASP A CG  1 
ATOM   179  O OD1 . ASP A 1 61  ? -80.90399 -126.52054 -14.37940 1.000 83.40502  ? 60  ASP A OD1 1 
ATOM   180  O OD2 . ASP A 1 61  ? -79.99373 -127.75152 -15.95206 1.000 83.26582  ? 60  ASP A OD2 1 
ATOM   181  N N   . ASN A 1 62  ? -83.51460 -126.95987 -12.24446 1.000 90.46341  ? 61  ASN A N   1 
ATOM   182  C CA  . ASN A 1 62  ? -83.40808 -127.22641 -10.80667 1.000 86.74729  ? 61  ASN A CA  1 
ATOM   183  C C   . ASN A 1 62  ? -82.03090 -127.76040 -10.41991 1.000 83.72481  ? 61  ASN A C   1 
ATOM   184  O O   . ASN A 1 62  ? -81.89868 -128.53813 -9.47153  1.000 86.05738  ? 61  ASN A O   1 
ATOM   185  C CB  . ASN A 1 62  ? -84.50690 -128.18353 -10.33489 1.000 89.00834  ? 61  ASN A CB  1 
ATOM   186  C CG  . ASN A 1 62  ? -85.87211 -127.52695 -10.29993 1.000 92.89037  ? 61  ASN A CG  1 
ATOM   187  O OD1 . ASN A 1 62  ? -86.53219 -127.38544 -11.32905 1.000 95.23516  ? 61  ASN A OD1 1 
ATOM   188  N ND2 . ASN A 1 62  ? -86.30223 -127.11909 -9.11135  1.000 93.03802  ? 61  ASN A ND2 1 
ATOM   189  N N   . LEU A 1 63  ? -80.99780 -127.34716 -11.14353 1.000 80.44509  ? 62  LEU A N   1 
ATOM   190  C CA  . LEU A 1 63  ? -79.64195 -127.76470 -10.80984 1.000 74.85759  ? 62  LEU A CA  1 
ATOM   191  C C   . LEU A 1 63  ? -79.13063 -126.95000 -9.62738  1.000 73.13260  ? 62  LEU A C   1 
ATOM   192  O O   . LEU A 1 63  ? -79.18925 -125.71686 -9.66239  1.000 73.79653  ? 62  LEU A O   1 
ATOM   193  C CB  . LEU A 1 63  ? -78.71268 -127.59144 -12.00736 1.000 75.86240  ? 62  LEU A CB  1 
ATOM   194  C CG  . LEU A 1 63  ? -77.26669 -128.05724 -11.82387 1.000 71.40441  ? 62  LEU A CG  1 
ATOM   195  N N   . PRO A 1 64  ? -78.64366 -127.59381 -8.56851  1.000 66.42155  ? 63  PRO A N   1 
ATOM   196  C CA  . PRO A 1 64  ? -78.12034 -126.83897 -7.42236  1.000 69.05227  ? 63  PRO A CA  1 
ATOM   197  C C   . PRO A 1 64  ? -76.89507 -126.02538 -7.81473  1.000 65.24704  ? 63  PRO A C   1 
ATOM   198  O O   . PRO A 1 64  ? -75.92228 -126.55588 -8.35557  1.000 67.13045  ? 63  PRO A O   1 
ATOM   199  C CB  . PRO A 1 64  ? -77.77354 -127.93381 -6.40518  1.000 68.73140  ? 63  PRO A CB  1 
ATOM   200  C CG  . PRO A 1 64  ? -78.56841 -129.12871 -6.83626  1.000 69.40324  ? 63  PRO A CG  1 
ATOM   201  C CD  . PRO A 1 64  ? -78.63405 -129.04483 -8.32679  1.000 67.68547  ? 63  PRO A CD  1 
ATOM   202  N N   . VAL A 1 65  ? -76.95274 -124.72098 -7.54257  1.000 63.32318  ? 64  VAL A N   1 
ATOM   203  C CA  . VAL A 1 65  ? -75.87160 -123.80493 -7.87387  1.000 59.54271  ? 64  VAL A CA  1 
ATOM   204  C C   . VAL A 1 65  ? -75.50968 -122.99297 -6.63762  1.000 60.96695  ? 64  VAL A C   1 
ATOM   205  O O   . VAL A 1 65  ? -76.29917 -122.85026 -5.70157  1.000 61.08564  ? 64  VAL A O   1 
ATOM   206  C CB  . VAL A 1 65  ? -76.23322 -122.86059 -9.04503  1.000 58.27685  ? 64  VAL A CB  1 
ATOM   207  C CG1 . VAL A 1 65  ? -76.56169 -123.65676 -10.29856 1.000 59.58882  ? 64  VAL A CG1 1 
ATOM   208  C CG2 . VAL A 1 65  ? -77.39340 -121.95065 -8.66363  1.000 61.06311  ? 64  VAL A CG2 1 
ATOM   209  N N   . ALA A 1 66  ? -74.28872 -122.46627 -6.64326  1.000 54.85622  ? 65  ALA A N   1 
ATOM   210  C CA  . ALA A 1 66  ? -73.82612 -121.52416 -5.63432  1.000 53.09868  ? 65  ALA A CA  1 
ATOM   211  C C   . ALA A 1 66  ? -73.63862 -120.16480 -6.29103  1.000 50.18896  ? 65  ALA A C   1 
ATOM   212  O O   . ALA A 1 66  ? -72.93370 -120.05194 -7.29961  1.000 47.38809  ? 65  ALA A O   1 
ATOM   213  C CB  . ALA A 1 66  ? -72.51950 -121.99461 -4.98911  1.000 46.54297  ? 65  ALA A CB  1 
ATOM   214  N N   . ILE A 1 67  ? -74.27222 -119.14327 -5.72619  1.000 47.41754  ? 66  ILE A N   1 
ATOM   215  C CA  . ILE A 1 67  ? -74.26685 -117.80122 -6.29421  1.000 48.76363  ? 66  ILE A CA  1 
ATOM   216  C C   . ILE A 1 67  ? -73.32687 -116.94712 -5.45619  1.000 46.91530  ? 66  ILE A C   1 
ATOM   217  O O   . ILE A 1 67  ? -73.64120 -116.59459 -4.31381  1.000 46.97373  ? 66  ILE A O   1 
ATOM   218  C CB  . ILE A 1 67  ? -75.67876 -117.20601 -6.34181  1.000 49.30712  ? 66  ILE A CB  1 
ATOM   219  C CG1 . ILE A 1 67  ? -76.61079 -118.12290 -7.13464  1.000 46.09372  ? 66  ILE A CG1 1 
ATOM   220  C CG2 . ILE A 1 67  ? -75.64806 -115.82266 -6.95845  1.000 45.30791  ? 66  ILE A CG2 1 
ATOM   221  C CD1 . ILE A 1 67  ? -78.05516 -117.67096 -7.13761  1.000 53.24724  ? 66  ILE A CD1 1 
ATOM   222  N N   . LYS A 1 68  ? -72.17606 -116.60357 -6.02689  1.000 40.50356  ? 67  LYS A N   1 
ATOM   223  C CA  . LYS A 1 68  ? -71.10271 -115.92325 -5.31215  1.000 45.72984  ? 67  LYS A CA  1 
ATOM   224  C C   . LYS A 1 68  ? -71.01292 -114.47844 -5.78608  1.000 49.37996  ? 67  LYS A C   1 
ATOM   225  O O   . LYS A 1 68  ? -70.82209 -114.22242 -6.98095  1.000 44.60404  ? 67  LYS A O   1 
ATOM   226  C CB  . LYS A 1 68  ? -69.77345 -116.64936 -5.52413  1.000 41.28986  ? 67  LYS A CB  1 
ATOM   227  C CG  . LYS A 1 68  ? -68.55657 -115.94895 -4.94120  1.000 49.07102  ? 67  LYS A CG  1 
ATOM   228  C CD  . LYS A 1 68  ? -67.29394 -116.77007 -5.19499  1.000 51.16679  ? 67  LYS A CD  1 
ATOM   229  C CE  . LYS A 1 68  ? -66.03923 -116.03616 -4.75520  1.000 55.67201  ? 67  LYS A CE  1 
ATOM   230  N NZ  . LYS A 1 68  ? -64.83262 -116.91160 -4.79216  1.000 48.56003  ? 67  LYS A NZ  1 
ATOM   231  N N   . HIS A 1 69  ? -71.14836 -113.54323 -4.84961  1.000 46.93900  ? 68  HIS A N   1 
ATOM   232  C CA  . HIS A 1 69  ? -71.05763 -112.11755 -5.12930  1.000 47.00330  ? 68  HIS A CA  1 
ATOM   233  C C   . HIS A 1 69  ? -69.70137 -111.58976 -4.68695  1.000 50.72064  ? 68  HIS A C   1 
ATOM   234  O O   . HIS A 1 69  ? -69.22867 -111.90644 -3.59133  1.000 51.08343  ? 68  HIS A O   1 
ATOM   235  C CB  . HIS A 1 69  ? -72.16705 -111.34486 -4.41173  1.000 45.37574  ? 68  HIS A CB  1 
ATOM   236  C CG  . HIS A 1 69  ? -73.54754 -111.77692 -4.79125  1.000 46.18260  ? 68  HIS A CG  1 
ATOM   237  N ND1 . HIS A 1 69  ? -74.39772 -110.98317 -5.52975  1.000 43.10643  ? 68  HIS A ND1 1 
ATOM   238  C CD2 . HIS A 1 69  ? -74.22574 -112.92123 -4.53759  1.000 46.81496  ? 68  HIS A CD2 1 
ATOM   239  C CE1 . HIS A 1 69  ? -75.54004 -111.61998 -5.71596  1.000 47.31899  ? 68  HIS A CE1 1 
ATOM   240  N NE2 . HIS A 1 69  ? -75.46092 -112.79883 -5.12533  1.000 48.70845  ? 68  HIS A NE2 1 
ATOM   241  N N   . VAL A 1 70  ? -69.08097 -110.78015 -5.54215  1.000 45.26574  ? 69  VAL A N   1 
ATOM   242  C CA  . VAL A 1 70  ? -67.78803 -110.16708 -5.25850  1.000 50.32953  ? 69  VAL A CA  1 
ATOM   243  C C   . VAL A 1 70  ? -67.89322 -108.68021 -5.56644  1.000 54.51859  ? 69  VAL A C   1 
ATOM   244  O O   . VAL A 1 70  ? -68.27626 -108.30185 -6.67921  1.000 52.12935  ? 69  VAL A O   1 
ATOM   245  C CB  . VAL A 1 70  ? -66.65346 -110.80660 -6.07663  1.000 54.75113  ? 69  VAL A CB  1 
ATOM   246  C CG1 . VAL A 1 70  ? -65.33663 -110.10552 -5.79064  1.000 59.71819  ? 69  VAL A CG1 1 
ATOM   247  C CG2 . VAL A 1 70  ? -66.54720 -112.29573 -5.77639  1.000 54.20726  ? 69  VAL A CG2 1 
ATOM   248  N N   . GLU A 1 71  ? -67.55049 -107.84194 -4.59085  1.000 52.60379  ? 70  GLU A N   1 
ATOM   249  C CA  . GLU A 1 71  ? -67.58283 -106.39992 -4.79813  1.000 57.77869  ? 70  GLU A CA  1 
ATOM   250  C C   . GLU A 1 71  ? -66.41724 -105.95634 -5.67330  1.000 58.58277  ? 70  GLU A C   1 
ATOM   251  O O   . GLU A 1 71  ? -65.29112 -106.44033 -5.52951  1.000 59.64693  ? 70  GLU A O   1 
ATOM   252  C CB  . GLU A 1 71  ? -67.54023 -105.66367 -3.45773  1.000 59.59770  ? 70  GLU A CB  1 
ATOM   253  C CG  . GLU A 1 71  ? -68.84023 -105.72126 -2.67389  1.000 58.44656  ? 70  GLU A CG  1 
ATOM   254  C CD  . GLU A 1 71  ? -68.74152 -105.03971 -1.31983  1.000 62.75676  ? 70  GLU A CD  1 
ATOM   255  O OE1 . GLU A 1 71  ? -67.61677 -104.66951 -0.91907  1.000 67.17443  ? 70  GLU A OE1 1 
ATOM   256  O OE2 . GLU A 1 71  ? -69.78905 -104.87520 -0.65621  1.000 56.72727  ? 70  GLU A OE2 1 
ATOM   257  N N   . LYS A 1 72  ? -66.69686 -105.02354 -6.58782  1.000 63.07277  ? 71  LYS A N   1 
ATOM   258  C CA  . LYS A 1 72  ? -65.65795 -104.53641 -7.48989  1.000 64.24182  ? 71  LYS A CA  1 
ATOM   259  C C   . LYS A 1 72  ? -64.55178 -103.81832 -6.72837  1.000 68.60803  ? 71  LYS A C   1 
ATOM   260  O O   . LYS A 1 72  ? -63.36719 -103.97374 -7.04714  1.000 70.66346  ? 71  LYS A O   1 
ATOM   261  C CB  . LYS A 1 72  ? -66.26527 -103.61030 -8.54298  1.000 62.58075  ? 71  LYS A CB  1 
ATOM   262  C CG  . LYS A 1 72  ? -67.10413 -104.31768 -9.59084  1.000 60.63954  ? 71  LYS A CG  1 
ATOM   263  C CD  . LYS A 1 72  ? -67.58240 -103.34057 -10.65024 1.000 65.97749  ? 71  LYS A CD  1 
ATOM   264  C CE  . LYS A 1 72  ? -68.32366 -104.05311 -11.76783 1.000 64.43875  ? 71  LYS A CE  1 
ATOM   265  N NZ  . LYS A 1 72  ? -68.77769 -103.10335 -12.81846 1.000 67.14196  ? 71  LYS A NZ  1 
ATOM   266  N N   . ASP A 1 73  ? -64.91704 -103.03032 -5.71529  1.000 68.88988  ? 72  ASP A N   1 
ATOM   267  C CA  . ASP A 1 73  ? -63.93475 -102.26551 -4.95647  1.000 75.29737  ? 72  ASP A CA  1 
ATOM   268  C C   . ASP A 1 73  ? -63.00998 -103.14234 -4.12138  1.000 74.72472  ? 72  ASP A C   1 
ATOM   269  O O   . ASP A 1 73  ? -62.01175 -102.63367 -3.60038  1.000 78.68028  ? 72  ASP A O   1 
ATOM   270  C CB  . ASP A 1 73  ? -64.64573 -101.25479 -4.05315  1.000 81.58509  ? 72  ASP A CB  1 
ATOM   271  C CG  . ASP A 1 73  ? -65.37332 -100.18003 -4.84029  1.000 87.14438  ? 72  ASP A CG  1 
ATOM   272  O OD1 . ASP A 1 73  ? -65.23222 -100.15155 -6.08136  1.000 88.09980  ? 72  ASP A OD1 1 
ATOM   273  O OD2 . ASP A 1 73  ? -66.08697 -99.36388  -4.21900  1.000 90.65634  ? 72  ASP A OD2 1 
ATOM   274  N N   . ARG A 1 74  ? -63.30696 -104.43560 -3.98427  1.000 72.80971  ? 73  ARG A N   1 
ATOM   275  C CA  . ARG A 1 74  ? -62.48273 -105.35147 -3.20592  1.000 71.96321  ? 73  ARG A CA  1 
ATOM   276  C C   . ARG A 1 74  ? -61.73518 -106.35063 -4.08308  1.000 73.36235  ? 73  ARG A C   1 
ATOM   277  O O   . ARG A 1 74  ? -61.27567 -107.38326 -3.58533  1.000 76.94646  ? 73  ARG A O   1 
ATOM   278  C CB  . ARG A 1 74  ? -63.33928 -106.09057 -2.17718  1.000 69.64522  ? 73  ARG A CB  1 
ATOM   279  N N   . ILE A 1 75  ? -61.60108 -106.06651 -5.37623  1.000 74.31430  ? 74  ILE A N   1 
ATOM   280  C CA  . ILE A 1 75  ? -60.93502 -106.96142 -6.31667  1.000 75.04467  ? 74  ILE A CA  1 
ATOM   281  C C   . ILE A 1 75  ? -59.51130 -106.47161 -6.53245  1.000 76.51583  ? 74  ILE A C   1 
ATOM   282  O O   . ILE A 1 75  ? -59.29518 -105.30514 -6.88959  1.000 75.94002  ? 74  ILE A O   1 
ATOM   283  C CB  . ILE A 1 75  ? -61.69894 -107.03811 -7.64900  1.000 70.85846  ? 74  ILE A CB  1 
ATOM   284  C CG1 . ILE A 1 75  ? -63.06299 -107.69703 -7.44034  1.000 66.84723  ? 74  ILE A CG1 1 
ATOM   285  C CG2 . ILE A 1 75  ? -60.88958 -107.80377 -8.68486  1.000 71.70066  ? 74  ILE A CG2 1 
ATOM   286  C CD1 . ILE A 1 75  ? -63.96136 -107.63022 -8.64894  1.000 64.33143  ? 74  ILE A CD1 1 
ATOM   287  N N   . SER A 1 76  ? -58.53890 -107.36277 -6.32390  1.000 84.89101  ? 75  SER A N   1 
ATOM   288  C CA  . SER A 1 76  ? -57.13831 -106.97453 -6.44786  1.000 82.60927  ? 75  SER A CA  1 
ATOM   289  C C   . SER A 1 76  ? -56.65531 -107.09059 -7.89051  1.000 80.03436  ? 75  SER A C   1 
ATOM   290  O O   . SER A 1 76  ? -56.28691 -106.09289 -8.51714  1.000 83.99011  ? 75  SER A O   1 
ATOM   291  C CB  . SER A 1 76  ? -56.27598 -107.83086 -5.51903  1.000 85.90543  ? 75  SER A CB  1 
ATOM   292  N N   . ASP A 1 77  ? -56.65479 -108.30224 -8.43537  1.000 77.11156  ? 76  ASP A N   1 
ATOM   293  C CA  . ASP A 1 77  ? -56.14301 -108.56263 -9.77541  1.000 77.10751  ? 76  ASP A CA  1 
ATOM   294  C C   . ASP A 1 77  ? -57.29231 -108.60159 -10.77422 1.000 70.37369  ? 76  ASP A C   1 
ATOM   295  O O   . ASP A 1 77  ? -58.31013 -109.26066 -10.53555 1.000 66.82009  ? 76  ASP A O   1 
ATOM   296  C CB  . ASP A 1 77  ? -55.36161 -109.87817 -9.81284  1.000 76.03612  ? 76  ASP A CB  1 
ATOM   297  C CG  . ASP A 1 77  ? -54.21326 -109.89924 -8.82227  1.000 77.44956  ? 76  ASP A CG  1 
ATOM   298  N N   . TRP A 1 78  ? -57.12477 -107.89627 -11.88745 1.000 69.95029  ? 77  TRP A N   1 
ATOM   299  C CA  . TRP A 1 78  ? -58.11057 -107.85646 -12.95510 1.000 67.33023  ? 77  TRP A CA  1 
ATOM   300  C C   . TRP A 1 78  ? -57.55371 -108.51930 -14.20724 1.000 67.06054  ? 77  TRP A C   1 
ATOM   301  O O   . TRP A 1 78  ? -56.34539 -108.49945 -14.45797 1.000 72.49948  ? 77  TRP A O   1 
ATOM   302  C CB  . TRP A 1 78  ? -58.52573 -106.41759 -13.27626 1.000 67.59413  ? 77  TRP A CB  1 
ATOM   303  C CG  . TRP A 1 78  ? -59.45408 -105.81592 -12.26979 1.000 69.03053  ? 77  TRP A CG  1 
ATOM   304  C CD1 . TRP A 1 78  ? -59.11235 -105.21953 -11.09075 1.000 71.79526  ? 77  TRP A CD1 1 
ATOM   305  C CD2 . TRP A 1 78  ? -60.88179 -105.74420 -12.35705 1.000 66.99898  ? 77  TRP A CD2 1 
ATOM   306  N NE1 . TRP A 1 78  ? -60.23982 -104.78464 -10.43600 1.000 73.78964  ? 77  TRP A NE1 1 
ATOM   307  C CE2 . TRP A 1 78  ? -61.33929 -105.09349 -11.19317 1.000 71.74362  ? 77  TRP A CE2 1 
ATOM   308  C CE3 . TRP A 1 78  ? -61.81766 -106.16838 -13.30525 1.000 65.96888  ? 77  TRP A CE3 1 
ATOM   309  C CZ2 . TRP A 1 78  ? -62.69185 -104.85664 -10.95225 1.000 68.40963  ? 77  TRP A CZ2 1 
ATOM   310  C CZ3 . TRP A 1 78  ? -63.15989 -105.93272 -13.06470 1.000 68.12224  ? 77  TRP A CZ3 1 
ATOM   311  C CH2 . TRP A 1 78  ? -63.58422 -105.28213 -11.89756 1.000 65.94873  ? 77  TRP A CH2 1 
ATOM   312  N N   . GLY A 1 79  ? -58.45369 -109.11225 -14.99218 1.000 66.72301  ? 78  GLY A N   1 
ATOM   313  C CA  . GLY A 1 79  ? -58.08820 -109.75764 -16.23459 1.000 66.88541  ? 78  GLY A CA  1 
ATOM   314  C C   . GLY A 1 79  ? -58.99683 -109.31579 -17.36755 1.000 73.21783  ? 78  GLY A C   1 
ATOM   315  O O   . GLY A 1 79  ? -59.89212 -108.48737 -17.18818 1.000 76.21305  ? 78  GLY A O   1 
ATOM   316  N N   . GLU A 1 80  ? -58.74239 -109.89314 -18.53906 1.000 75.93569  ? 79  GLU A N   1 
ATOM   317  C CA  . GLU A 1 80  ? -59.49320 -109.56454 -19.74270 1.000 86.17973  ? 79  GLU A CA  1 
ATOM   318  C C   . GLU A 1 80  ? -59.84572 -110.84543 -20.48061 1.000 88.94883  ? 79  GLU A C   1 
ATOM   319  O O   . GLU A 1 80  ? -58.98127 -111.70059 -20.69425 1.000 89.16183  ? 79  GLU A O   1 
ATOM   320  C CB  . GLU A 1 80  ? -58.69608 -108.62671 -20.65858 1.000 84.81233  ? 79  GLU A CB  1 
ATOM   321  N N   . LEU A 1 81  ? -61.11318 -110.97256 -20.86190 1.000 91.81264  ? 80  LEU A N   1 
ATOM   322  C CA  . LEU A 1 81  ? -61.57223 -112.11050 -21.63799 1.000 99.17000  ? 80  LEU A CA  1 
ATOM   323  C C   . LEU A 1 81  ? -61.18991 -111.93660 -23.10610 1.000 101.84688 ? 80  LEU A C   1 
ATOM   324  O O   . LEU A 1 81  ? -60.80526 -110.84283 -23.53093 1.000 102.25460 ? 80  LEU A O   1 
ATOM   325  C CB  . LEU A 1 81  ? -63.08371 -112.26543 -21.49601 1.000 96.81078  ? 80  LEU A CB  1 
ATOM   326  N N   . PRO A 1 82  ? -61.24836 -113.01695 -23.89570 1.000 103.47667 ? 81  PRO A N   1 
ATOM   327  C CA  . PRO A 1 82  ? -61.02782 -112.87975 -25.34771 1.000 102.82051 ? 81  PRO A CA  1 
ATOM   328  C C   . PRO A 1 82  ? -61.83229 -111.75941 -25.99147 1.000 102.08706 ? 81  PRO A C   1 
ATOM   329  O O   . PRO A 1 82  ? -61.34130 -111.10460 -26.91886 1.000 104.01001 ? 81  PRO A O   1 
ATOM   330  C CB  . PRO A 1 82  ? -61.44750 -114.25366 -25.89049 1.000 101.96960 ? 81  PRO A CB  1 
ATOM   331  C CG  . PRO A 1 82  ? -61.37290 -115.20067 -24.71887 1.000 103.79382 ? 81  PRO A CG  1 
ATOM   332  C CD  . PRO A 1 82  ? -61.15846 -114.41992 -23.45479 1.000 102.64597 ? 81  PRO A CD  1 
ATOM   333  N N   . ASN A 1 83  ? -63.05767 -111.51692 -25.52193 1.000 103.46109 ? 82  ASN A N   1 
ATOM   334  C CA  . ASN A 1 83  ? -63.87495 -110.42814 -26.04611 1.000 101.20762 ? 82  ASN A CA  1 
ATOM   335  C C   . ASN A 1 83  ? -63.38918 -109.05261 -25.60522 1.000 102.58269 ? 82  ASN A C   1 
ATOM   336  O O   . ASN A 1 83  ? -63.97281 -108.04844 -26.02818 1.000 100.70447 ? 82  ASN A O   1 
ATOM   337  C CB  . ASN A 1 83  ? -65.33339 -110.61847 -25.62372 1.000 100.06038 ? 82  ASN A CB  1 
ATOM   338  N N   . GLY A 1 84  ? -62.35055 -108.97689 -24.77216 1.000 103.56425 ? 83  GLY A N   1 
ATOM   339  C CA  . GLY A 1 84  ? -61.81751 -107.71327 -24.31409 1.000 101.62095 ? 83  GLY A CA  1 
ATOM   340  C C   . GLY A 1 84  ? -62.46174 -107.15552 -23.06313 1.000 100.33506 ? 83  GLY A C   1 
ATOM   341  O O   . GLY A 1 84  ? -61.97186 -106.15042 -22.53103 1.000 99.22752  ? 83  GLY A O   1 
ATOM   342  N N   . THR A 1 85  ? -63.53811 -107.76894 -22.57589 1.000 98.69600  ? 84  THR A N   1 
ATOM   343  C CA  . THR A 1 85  ? -64.21195 -107.27074 -21.38422 1.000 94.54420  ? 84  THR A CA  1 
ATOM   344  C C   . THR A 1 85  ? -63.32302 -107.44948 -20.15900 1.000 89.34555  ? 84  THR A C   1 
ATOM   345  O O   . THR A 1 85  ? -62.71487 -108.50721 -19.96815 1.000 86.94977  ? 84  THR A O   1 
ATOM   346  C CB  . THR A 1 85  ? -65.54093 -107.99690 -21.18301 1.000 89.88021  ? 84  THR A CB  1 
ATOM   347  N N   . ARG A 1 86  ? -63.24695 -106.41029 -19.32936 1.000 84.44561  ? 85  ARG A N   1 
ATOM   348  C CA  . ARG A 1 86  ? -62.42635 -106.44211 -18.12254 1.000 79.83600  ? 85  ARG A CA  1 
ATOM   349  C C   . ARG A 1 86  ? -63.19188 -107.16804 -17.02242 1.000 76.51789  ? 85  ARG A C   1 
ATOM   350  O O   . ARG A 1 86  ? -64.17740 -106.64566 -16.49086 1.000 74.50784  ? 85  ARG A O   1 
ATOM   351  C CB  . ARG A 1 86  ? -62.05134 -105.02692 -17.69236 1.000 78.67518  ? 85  ARG A CB  1 
ATOM   352  N N   . VAL A 1 87  ? -62.74086 -108.36690 -16.68085 1.000 73.42543  ? 86  VAL A N   1 
ATOM   353  C CA  . VAL A 1 87  ? -63.39760 -109.19448 -15.67217 1.000 66.06739  ? 86  VAL A CA  1 
ATOM   354  C C   . VAL A 1 87  ? -62.39525 -109.44445 -14.55664 1.000 63.04154  ? 86  VAL A C   1 
ATOM   355  O O   . VAL A 1 87  ? -61.17936 -109.25866 -14.74059 1.000 63.61766  ? 86  VAL A O   1 
ATOM   356  C CB  . VAL A 1 87  ? -63.92706 -110.51771 -16.27364 1.000 63.33029  ? 86  VAL A CB  1 
ATOM   357  C CG1 . VAL A 1 87  ? -64.90097 -110.23658 -17.40758 1.000 65.85869  ? 86  VAL A CG1 1 
ATOM   358  C CG2 . VAL A 1 87  ? -62.77478 -111.37942 -16.75454 1.000 64.02879  ? 86  VAL A CG2 1 
ATOM   359  N N   . PRO A 1 88  ? -62.86383 -109.84482 -13.37319 1.000 58.38788  ? 87  PRO A N   1 
ATOM   360  C CA  . PRO A 1 88  ? -61.92619 -110.24008 -12.31786 1.000 58.95257  ? 87  PRO A CA  1 
ATOM   361  C C   . PRO A 1 88  ? -61.08546 -111.42630 -12.76108 1.000 52.91601  ? 87  PRO A C   1 
ATOM   362  O O   . PRO A 1 88  ? -61.54155 -112.29054 -13.51265 1.000 49.26806  ? 87  PRO A O   1 
ATOM   363  C CB  . PRO A 1 88  ? -62.84087 -110.61053 -11.14436 1.000 57.21209  ? 87  PRO A CB  1 
ATOM   364  C CG  . PRO A 1 88  ? -64.10944 -109.88401 -11.40939 1.000 59.94397  ? 87  PRO A CG  1 
ATOM   365  C CD  . PRO A 1 88  ? -64.25848 -109.84236 -12.89715 1.000 57.26217  ? 87  PRO A CD  1 
ATOM   366  N N   . MET A 1 89  ? -59.83588 -111.45429 -12.28940 1.000 51.71689  ? 88  MET A N   1 
ATOM   367  C CA  . MET A 1 89  ? -58.94741 -112.56160 -12.62786 1.000 54.34563  ? 88  MET A CA  1 
ATOM   368  C C   . MET A 1 89  ? -59.54179 -113.90244 -12.21457 1.000 46.98762  ? 88  MET A C   1 
ATOM   369  O O   . MET A 1 89  ? -59.31357 -114.91383 -12.88745 1.000 44.71337  ? 88  MET A O   1 
ATOM   370  C CB  . MET A 1 89  ? -57.58053 -112.35671 -11.97338 1.000 59.85459  ? 88  MET A CB  1 
ATOM   371  C CG  . MET A 1 89  ? -56.53176 -113.39194 -12.36426 1.000 56.31397  ? 88  MET A CG  1 
ATOM   372  S SD  . MET A 1 89  ? -56.16208 -113.40688 -14.13053 1.000 67.37932  ? 88  MET A SD  1 
ATOM   373  C CE  . MET A 1 89  ? -55.65420 -111.70977 -14.38731 1.000 59.30471  ? 88  MET A CE  1 
ATOM   374  N N   . GLU A 1 90  ? -60.31669 -113.92582 -11.12538 1.000 46.00019  ? 89  GLU A N   1 
ATOM   375  C CA  . GLU A 1 90  ? -60.95319 -115.16411 -10.68575 1.000 45.56468  ? 89  GLU A CA  1 
ATOM   376  C C   . GLU A 1 90  ? -61.82647 -115.75740 -11.78464 1.000 43.96843  ? 89  GLU A C   1 
ATOM   377  O O   . GLU A 1 90  ? -61.84586 -116.97875 -11.98201 1.000 39.02145  ? 89  GLU A O   1 
ATOM   378  C CB  . GLU A 1 90  ? -61.77528 -114.90851 -9.41955  1.000 45.48724  ? 89  GLU A CB  1 
ATOM   379  C CG  . GLU A 1 90  ? -62.51789 -116.13128 -8.89499  1.000 42.46813  ? 89  GLU A CG  1 
ATOM   380  C CD  . GLU A 1 90  ? -63.24762 -115.86943 -7.58799  1.000 44.81536  ? 89  GLU A CD  1 
ATOM   381  O OE1 . GLU A 1 90  ? -63.14862 -114.74342 -7.05797  1.000 43.54657  ? 89  GLU A OE1 1 
ATOM   382  O OE2 . GLU A 1 90  ? -63.92090 -116.79542 -7.08887  1.000 43.01221  ? 89  GLU A OE2 1 
ATOM   383  N N   . VAL A 1 91  ? -62.54899 -114.90765 -12.51723 1.000 43.75845  ? 90  VAL A N   1 
ATOM   384  C CA  . VAL A 1 91  ? -63.36970 -115.39502 -13.62145 1.000 42.49522  ? 90  VAL A CA  1 
ATOM   385  C C   . VAL A 1 91  ? -62.49278 -115.98632 -14.71914 1.000 42.55981  ? 90  VAL A C   1 
ATOM   386  O O   . VAL A 1 91  ? -62.80989 -117.04076 -15.28256 1.000 42.02431  ? 90  VAL A O   1 
ATOM   387  C CB  . VAL A 1 91  ? -64.26959 -114.26465 -14.15491 1.000 50.00606  ? 90  VAL A CB  1 
ATOM   388  C CG1 . VAL A 1 91  ? -65.03933 -114.72438 -15.38477 1.000 50.26804  ? 90  VAL A CG1 1 
ATOM   389  C CG2 . VAL A 1 91  ? -65.22640 -113.79533 -13.07129 1.000 47.56799  ? 90  VAL A CG2 1 
ATOM   390  N N   . VAL A 1 92  ? -61.37252 -115.32797 -15.03103 1.000 43.36324  ? 91  VAL A N   1 
ATOM   391  C CA  . VAL A 1 92  ? -60.46465 -115.83771 -16.05722 1.000 42.47211  ? 91  VAL A CA  1 
ATOM   392  C C   . VAL A 1 92  ? -59.95473 -117.22195 -15.67515 1.000 42.63887  ? 91  VAL A C   1 
ATOM   393  O O   . VAL A 1 92  ? -59.95830 -118.15232 -16.48981 1.000 38.59859  ? 91  VAL A O   1 
ATOM   394  C CB  . VAL A 1 92  ? -59.30346 -114.85208 -16.28505 1.000 46.73456  ? 91  VAL A CB  1 
ATOM   395  C CG1 . VAL A 1 92  ? -58.25738 -115.46214 -17.20839 1.000 45.60502  ? 91  VAL A CG1 1 
ATOM   396  C CG2 . VAL A 1 92  ? -59.82231 -113.54281 -16.85618 1.000 52.04633  ? 91  VAL A CG2 1 
ATOM   397  N N   . LEU A 1 93  ? -59.52212 -117.38155 -14.42202 1.000 41.07899  ? 92  LEU A N   1 
ATOM   398  C CA  . LEU A 1 93  ? -58.96689 -118.65901 -13.98528 1.000 40.18921  ? 92  LEU A CA  1 
ATOM   399  C C   . LEU A 1 93  ? -60.03118 -119.74853 -13.95112 1.000 39.75072  ? 92  LEU A C   1 
ATOM   400  O O   . LEU A 1 93  ? -59.76925 -120.88882 -14.35097 1.000 38.20444  ? 92  LEU A O   1 
ATOM   401  C CB  . LEU A 1 93  ? -58.31728 -118.50346 -12.61068 1.000 38.43335  ? 92  LEU A CB  1 
ATOM   402  C CG  . LEU A 1 93  ? -57.25086 -117.41341 -12.50190 1.000 39.91049  ? 92  LEU A CG  1 
ATOM   403  C CD1 . LEU A 1 93  ? -56.72484 -117.34459 -11.07852 1.000 40.93241  ? 92  LEU A CD1 1 
ATOM   404  C CD2 . LEU A 1 93  ? -56.11473 -117.65853 -13.49064 1.000 37.26182  ? 92  LEU A CD2 1 
ATOM   405  N N   . LEU A 1 94  ? -61.23391 -119.42019 -13.47020 1.000 37.35066  ? 93  LEU A N   1 
ATOM   406  C CA  . LEU A 1 94  ? -62.30470 -120.41087 -13.41448 1.000 41.75522  ? 93  LEU A CA  1 
ATOM   407  C C   . LEU A 1 94  ? -62.67958 -120.90497 -14.80628 1.000 40.84975  ? 93  LEU A C   1 
ATOM   408  O O   . LEU A 1 94  ? -62.93252 -122.09955 -14.99902 1.000 41.20388  ? 93  LEU A O   1 
ATOM   409  C CB  . LEU A 1 94  ? -63.52571 -119.82676 -12.70139 1.000 39.45480  ? 93  LEU A CB  1 
ATOM   410  C CG  . LEU A 1 94  ? -63.44081 -119.75966 -11.17250 1.000 42.05457  ? 93  LEU A CG  1 
ATOM   411  C CD1 . LEU A 1 94  ? -64.59209 -118.94721 -10.59397 1.000 42.13833  ? 93  LEU A CD1 1 
ATOM   412  C CD2 . LEU A 1 94  ? -63.42354 -121.15599 -10.57482 1.000 39.73691  ? 93  LEU A CD2 1 
ATOM   413  N N   . LYS A 1 95  ? -62.71733 -120.00393 -15.79219 1.000 43.29618  ? 94  LYS A N   1 
ATOM   414  C CA  . LYS A 1 95  ? -63.03230 -120.42382 -17.15594 1.000 44.06774  ? 94  LYS A CA  1 
ATOM   415  C C   . LYS A 1 95  ? -61.96641 -121.36146 -17.70671 1.000 43.49118  ? 94  LYS A C   1 
ATOM   416  O O   . LYS A 1 95  ? -62.28247 -122.30928 -18.43576 1.000 47.79239  ? 94  LYS A O   1 
ATOM   417  C CB  . LYS A 1 95  ? -63.19073 -119.20671 -18.06967 1.000 44.13230  ? 94  LYS A CB  1 
ATOM   418  C CG  . LYS A 1 95  ? -64.44264 -118.37903 -17.80645 1.000 50.65639  ? 94  LYS A CG  1 
ATOM   419  C CD  . LYS A 1 95  ? -64.59481 -117.26644 -18.83697 1.000 55.87761  ? 94  LYS A CD  1 
ATOM   420  N N   . LYS A 1 96  ? -60.69939 -121.12043 -17.36510 1.000 42.29872  ? 95  LYS A N   1 
ATOM   421  C CA  . LYS A 1 96  ? -59.63193 -121.95516 -17.90213 1.000 40.90516  ? 95  LYS A CA  1 
ATOM   422  C C   . LYS A 1 96  ? -59.66342 -123.36739 -17.32553 1.000 42.54079  ? 95  LYS A C   1 
ATOM   423  O O   . LYS A 1 96  ? -59.22077 -124.31016 -17.99183 1.000 44.01738  ? 95  LYS A O   1 
ATOM   424  C CB  . LYS A 1 96  ? -58.27774 -121.29115 -17.65397 1.000 41.09450  ? 95  LYS A CB  1 
ATOM   425  C CG  . LYS A 1 96  ? -58.07944 -120.00789 -18.45880 1.000 44.44678  ? 95  LYS A CG  1 
ATOM   426  C CD  . LYS A 1 96  ? -56.83290 -119.25067 -18.02991 1.000 46.86177  ? 95  LYS A CD  1 
ATOM   427  C CE  . LYS A 1 96  ? -55.57133 -120.03065 -18.34825 1.000 46.89667  ? 95  LYS A CE  1 
ATOM   428  N NZ  . LYS A 1 96  ? -55.45674 -120.31564 -19.80847 1.000 54.67403  ? 95  LYS A NZ  1 
ATOM   429  N N   . VAL A 1 97  ? -60.18751 -123.54591 -16.10783 1.000 38.11184  ? 96  VAL A N   1 
ATOM   430  C CA  . VAL A 1 97  ? -60.25032 -124.87159 -15.49729 1.000 37.77690  ? 96  VAL A CA  1 
ATOM   431  C C   . VAL A 1 97  ? -61.62964 -125.50709 -15.60716 1.000 44.33363  ? 96  VAL A C   1 
ATOM   432  O O   . VAL A 1 97  ? -61.79080 -126.67667 -15.23349 1.000 44.40182  ? 96  VAL A O   1 
ATOM   433  C CB  . VAL A 1 97  ? -59.80621 -124.83726 -14.01930 1.000 43.86211  ? 96  VAL A CB  1 
ATOM   434  C CG1 . VAL A 1 97  ? -58.38666 -124.30550 -13.89999 1.000 38.48353  ? 96  VAL A CG1 1 
ATOM   435  C CG2 . VAL A 1 97  ? -60.77853 -124.01398 -13.18124 1.000 38.47259  ? 96  VAL A CG2 1 
ATOM   436  N N   . SER A 1 98  ? -62.62613 -124.78217 -16.11894 1.000 44.24099  ? 97  SER A N   1 
ATOM   437  C CA  . SER A 1 98  ? -63.98768 -125.29827 -16.22990 1.000 51.19527  ? 97  SER A CA  1 
ATOM   438  C C   . SER A 1 98  ? -64.13804 -126.31135 -17.35933 1.000 54.58475  ? 97  SER A C   1 
ATOM   439  O O   . SER A 1 98  ? -65.01591 -126.16362 -18.21395 1.000 71.59924  ? 97  SER A O   1 
ATOM   440  C CB  . SER A 1 98  ? -64.97302 -124.14641 -16.44426 1.000 57.07681  ? 97  SER A CB  1 
ATOM   441  N N   . SER A 1 99  ? -63.30585 -127.34901 -17.36502 1.000 60.40516  ? 98  SER A N   1 
ATOM   442  C CA  . SER A 1 99  ? -63.32055 -128.34833 -18.42479 1.000 65.47599  ? 98  SER A CA  1 
ATOM   443  C C   . SER A 1 99  ? -64.28378 -129.49653 -18.16136 1.000 72.69225  ? 98  SER A C   1 
ATOM   444  O O   . SER A 1 99  ? -64.48460 -130.32983 -19.05131 1.000 80.00342  ? 98  SER A O   1 
ATOM   445  C CB  . SER A 1 99  ? -61.91124 -128.91484 -18.63268 1.000 65.23694  ? 98  SER A CB  1 
ATOM   446  N N   . GLY A 1 100 ? -64.87976 -129.56453 -16.97493 1.000 74.97722  ? 99  GLY A N   1 
ATOM   447  C CA  . GLY A 1 100 ? -65.72246 -130.67747 -16.59576 1.000 75.42759  ? 99  GLY A CA  1 
ATOM   448  C C   . GLY A 1 100 ? -65.07494 -131.65682 -15.64086 1.000 81.77902  ? 99  GLY A C   1 
ATOM   449  O O   . GLY A 1 100 ? -65.77701 -132.51262 -15.08724 1.000 80.35953  ? 99  GLY A O   1 
ATOM   450  N N   . PHE A 1 101 ? -63.75993 -131.56630 -15.44639 1.000 77.13165  ? 100 PHE A N   1 
ATOM   451  C CA  . PHE A 1 101 ? -63.08376 -132.37564 -14.44115 1.000 63.42533  ? 100 PHE A CA  1 
ATOM   452  C C   . PHE A 1 101 ? -63.64590 -132.05190 -13.06627 1.000 62.69842  ? 100 PHE A C   1 
ATOM   453  O O   . PHE A 1 101 ? -63.58983 -130.90255 -12.61966 1.000 68.53469  ? 100 PHE A O   1 
ATOM   454  C CB  . PHE A 1 101 ? -61.57752 -132.11637 -14.48577 1.000 60.95798  ? 100 PHE A CB  1 
ATOM   455  C CG  . PHE A 1 101 ? -60.81140 -132.75506 -13.35927 1.000 57.11616  ? 100 PHE A CG  1 
ATOM   456  C CD1 . PHE A 1 101 ? -60.69292 -134.13374 -13.27537 1.000 58.53757  ? 100 PHE A CD1 1 
ATOM   457  C CD2 . PHE A 1 101 ? -60.19358 -131.97515 -12.39417 1.000 53.28866  ? 100 PHE A CD2 1 
ATOM   458  C CE1 . PHE A 1 101 ? -59.98191 -134.72356 -12.24194 1.000 53.21586  ? 100 PHE A CE1 1 
ATOM   459  C CE2 . PHE A 1 101 ? -59.47982 -132.55906 -11.35951 1.000 48.51581  ? 100 PHE A CE2 1 
ATOM   460  C CZ  . PHE A 1 101 ? -59.37597 -133.93353 -11.28229 1.000 46.60522  ? 100 PHE A CZ  1 
ATOM   461  N N   . SER A 1 102 ? -64.18911 -133.06975 -12.39715 1.000 63.28111  ? 101 SER A N   1 
ATOM   462  C CA  . SER A 1 102 ? -64.93511 -132.86341 -11.16310 1.000 61.05150  ? 101 SER A CA  1 
ATOM   463  C C   . SER A 1 102 ? -64.06432 -132.41043 -9.99607  1.000 53.34790  ? 101 SER A C   1 
ATOM   464  O O   . SER A 1 102 ? -64.61175 -132.06321 -8.94498  1.000 53.38782  ? 101 SER A O   1 
ATOM   465  C CB  . SER A 1 102 ? -65.67076 -134.14950 -10.77971 1.000 60.47980  ? 101 SER A CB  1 
ATOM   466  N N   . GLY A 1 103 ? -62.73876 -132.39728 -10.14305 1.000 51.02964  ? 102 GLY A N   1 
ATOM   467  C CA  . GLY A 1 103 ? -61.88187 -132.04957 -9.02372  1.000 44.07081  ? 102 GLY A CA  1 
ATOM   468  C C   . GLY A 1 103 ? -61.81011 -130.56743 -8.71742  1.000 42.95418  ? 102 GLY A C   1 
ATOM   469  O O   . GLY A 1 103 ? -61.28902 -130.20299 -7.65964  1.000 37.84381  ? 102 GLY A O   1 
ATOM   470  N N   . VAL A 1 104 ? -62.30101 -129.70905 -9.61077  1.000 43.59869  ? 103 VAL A N   1 
ATOM   471  C CA  . VAL A 1 104 ? -62.31350 -128.27131 -9.38004  1.000 42.11201  ? 103 VAL A CA  1 
ATOM   472  C C   . VAL A 1 104 ? -63.74785 -127.77928 -9.48208  1.000 42.51277  ? 103 VAL A C   1 
ATOM   473  O O   . VAL A 1 104 ? -64.57980 -128.36908 -10.18051 1.000 41.13659  ? 103 VAL A O   1 
ATOM   474  C CB  . VAL A 1 104 ? -61.40309 -127.51291 -10.37347 1.000 42.23811  ? 103 VAL A CB  1 
ATOM   475  C CG1 . VAL A 1 104 ? -59.97374 -128.01944 -10.28485 1.000 39.16774  ? 103 VAL A CG1 1 
ATOM   476  C CG2 . VAL A 1 104 ? -61.93683 -127.63922 -11.79560 1.000 41.01789  ? 103 VAL A CG2 1 
ATOM   477  N N   . ILE A 1 105 ? -64.03774 -126.69031 -8.76906  1.000 40.00390  ? 104 ILE A N   1 
ATOM   478  C CA  . ILE A 1 105 ? -65.35949 -126.08485 -8.85739  1.000 41.38693  ? 104 ILE A CA  1 
ATOM   479  C C   . ILE A 1 105 ? -65.58050 -125.56994 -10.27444 1.000 43.67150  ? 104 ILE A C   1 
ATOM   480  O O   . ILE A 1 105 ? -64.66992 -125.01763 -10.90947 1.000 44.42693  ? 104 ILE A O   1 
ATOM   481  C CB  . ILE A 1 105 ? -65.52132 -124.96845 -7.80983  1.000 46.48123  ? 104 ILE A CB  1 
ATOM   482  C CG1 . ILE A 1 105 ? -67.00224 -124.65722 -7.58480  1.000 45.58421  ? 104 ILE A CG1 1 
ATOM   483  C CG2 . ILE A 1 105 ? -64.74120 -123.70902 -8.19877  1.000 40.87973  ? 104 ILE A CG2 1 
ATOM   484  C CD1 . ILE A 1 105 ? -67.72800 -125.73042 -6.79986  1.000 50.67609  ? 104 ILE A CD1 1 
ATOM   485  N N   . ARG A 1 106 ? -66.78464 -125.78296 -10.79483 1.000 42.97982  ? 105 ARG A N   1 
ATOM   486  C CA  . ARG A 1 106 ? -67.10708 -125.45055 -12.17604 1.000 46.51839  ? 105 ARG A CA  1 
ATOM   487  C C   . ARG A 1 106 ? -67.89604 -124.14784 -12.21490 1.000 46.36492  ? 105 ARG A C   1 
ATOM   488  O O   . ARG A 1 106 ? -68.95177 -124.03685 -11.58238 1.000 43.01987  ? 105 ARG A O   1 
ATOM   489  C CB  . ARG A 1 106 ? -67.89907 -126.58012 -12.83463 1.000 42.54003  ? 105 ARG A CB  1 
ATOM   490  C CG  . ARG A 1 106 ? -68.23849 -126.33048 -14.29539 1.000 52.03407  ? 105 ARG A CG  1 
ATOM   491  N N   . LEU A 1 107 ? -67.37963 -123.16798 -12.95185 1.000 44.05465  ? 106 LEU A N   1 
ATOM   492  C CA  . LEU A 1 107 ? -68.10221 -121.92627 -13.19400 1.000 45.45871  ? 106 LEU A CA  1 
ATOM   493  C C   . LEU A 1 107 ? -69.10324 -122.14160 -14.32167 1.000 45.52529  ? 106 LEU A C   1 
ATOM   494  O O   . LEU A 1 107 ? -68.71417 -122.46660 -15.44725 1.000 46.79288  ? 106 LEU A O   1 
ATOM   495  C CB  . LEU A 1 107 ? -67.13190 -120.80175 -13.54609 1.000 44.81945  ? 106 LEU A CB  1 
ATOM   496  C CG  . LEU A 1 107 ? -67.76033 -119.44615 -13.88345 1.000 47.43984  ? 106 LEU A CG  1 
ATOM   497  C CD1 . LEU A 1 107 ? -68.39940 -118.82363 -12.64652 1.000 43.99836  ? 106 LEU A CD1 1 
ATOM   498  C CD2 . LEU A 1 107 ? -66.72633 -118.50831 -14.48751 1.000 47.94136  ? 106 LEU A CD2 1 
ATOM   499  N N   . LEU A 1 108 ? -70.38832 -121.95874 -14.02058 1.000 45.05836  ? 107 LEU A N   1 
ATOM   500  C CA  . LEU A 1 108 ? -71.44650 -122.16290 -15.00171 1.000 48.10710  ? 107 LEU A CA  1 
ATOM   501  C C   . LEU A 1 108 ? -71.79987 -120.89357 -15.76157 1.000 50.76920  ? 107 LEU A C   1 
ATOM   502  O O   . LEU A 1 108 ? -72.16637 -120.96859 -16.94054 1.000 51.30163  ? 107 LEU A O   1 
ATOM   503  C CB  . LEU A 1 108 ? -72.70541 -122.70463 -14.31576 1.000 47.50247  ? 107 LEU A CB  1 
ATOM   504  C CG  . LEU A 1 108 ? -72.53176 -123.98719 -13.50138 1.000 47.32323  ? 107 LEU A CG  1 
ATOM   505  C CD1 . LEU A 1 108 ? -73.80739 -124.32501 -12.74976 1.000 53.61308  ? 107 LEU A CD1 1 
ATOM   506  C CD2 . LEU A 1 108 ? -72.11895 -125.13867 -14.40348 1.000 53.48001  ? 107 LEU A CD2 1 
ATOM   507  N N   . ASP A 1 109 ? -71.70099 -119.73481 -15.11746 1.000 47.28461  ? 108 ASP A N   1 
ATOM   508  C CA  . ASP A 1 109 ? -72.08174 -118.46820 -15.72990 1.000 49.71232  ? 108 ASP A CA  1 
ATOM   509  C C   . ASP A 1 109 ? -71.60051 -117.35628 -14.81036 1.000 51.86860  ? 108 ASP A C   1 
ATOM   510  O O   . ASP A 1 109 ? -71.16705 -117.60502 -13.68188 1.000 47.17840  ? 108 ASP A O   1 
ATOM   511  C CB  . ASP A 1 109 ? -73.59655 -118.38574 -15.95467 1.000 53.63810  ? 108 ASP A CB  1 
ATOM   512  C CG  . ASP A 1 109 ? -73.98626 -117.33859 -16.98915 1.000 58.22701  ? 108 ASP A CG  1 
ATOM   513  O OD1 . ASP A 1 109 ? -73.08546 -116.75344 -17.62815 1.000 53.08973  ? 108 ASP A OD1 1 
ATOM   514  O OD2 . ASP A 1 109 ? -75.20105 -117.10279 -17.15639 1.000 61.25984  ? 108 ASP A OD2 1 
ATOM   515  N N   . TRP A 1 110 ? -71.67999 -116.12445 -15.30623 1.000 48.49345  ? 109 TRP A N   1 
ATOM   516  C CA  . TRP A 1 110 ? -71.33075 -114.96611 -14.49849 1.000 49.83959  ? 109 TRP A CA  1 
ATOM   517  C C   . TRP A 1 110 ? -72.01964 -113.73738 -15.07157 1.000 57.51814  ? 109 TRP A C   1 
ATOM   518  O O   . TRP A 1 110 ? -72.36307 -113.69447 -16.25672 1.000 56.42749  ? 109 TRP A O   1 
ATOM   519  C CB  . TRP A 1 110 ? -69.81363 -114.75611 -14.42974 1.000 49.04747  ? 109 TRP A CB  1 
ATOM   520  C CG  . TRP A 1 110 ? -69.17117 -114.58048 -15.76502 1.000 53.86999  ? 109 TRP A CG  1 
ATOM   521  C CD1 . TRP A 1 110 ? -68.69119 -115.56345 -16.57957 1.000 53.27387  ? 109 TRP A CD1 1 
ATOM   522  C CD2 . TRP A 1 110 ? -68.92922 -113.34295 -16.44217 1.000 55.87604  ? 109 TRP A CD2 1 
ATOM   523  N NE1 . TRP A 1 110 ? -68.16858 -115.01444 -17.72536 1.000 59.21028  ? 109 TRP A NE1 1 
ATOM   524  C CE2 . TRP A 1 110 ? -68.30351 -113.65238 -17.66593 1.000 57.38216  ? 109 TRP A CE2 1 
ATOM   525  C CE3 . TRP A 1 110 ? -69.18539 -112.00309 -16.13453 1.000 57.73825  ? 109 TRP A CE3 1 
ATOM   526  C CZ2 . TRP A 1 110 ? -67.92951 -112.67226 -18.58134 1.000 59.98780  ? 109 TRP A CZ2 1 
ATOM   527  C CZ3 . TRP A 1 110 ? -68.81290 -111.03063 -17.04522 1.000 65.19171  ? 109 TRP A CZ3 1 
ATOM   528  C CH2 . TRP A 1 110 ? -68.19293 -111.37038 -18.25433 1.000 59.08659  ? 109 TRP A CH2 1 
ATOM   529  N N   . PHE A 1 111 ? -72.22033 -112.74434 -14.21056 1.000 52.51046  ? 110 PHE A N   1 
ATOM   530  C CA  . PHE A 1 111 ? -72.88729 -111.50572 -14.57339 1.000 56.46052  ? 110 PHE A CA  1 
ATOM   531  C C   . PHE A 1 111 ? -72.10479 -110.33327 -14.00379 1.000 56.32866  ? 110 PHE A C   1 
ATOM   532  O O   . PHE A 1 111 ? -71.40084 -110.45895 -12.99843 1.000 55.22850  ? 110 PHE A O   1 
ATOM   533  C CB  . PHE A 1 111 ? -74.32983 -111.45772 -14.04668 1.000 56.47717  ? 110 PHE A CB  1 
ATOM   534  C CG  . PHE A 1 111 ? -75.16606 -112.63908 -14.44254 1.000 63.90815  ? 110 PHE A CG  1 
ATOM   535  C CD1 . PHE A 1 111 ? -75.17446 -113.78816 -13.66980 1.000 62.70657  ? 110 PHE A CD1 1 
ATOM   536  C CD2 . PHE A 1 111 ? -75.95469 -112.59617 -15.58088 1.000 73.21409  ? 110 PHE A CD2 1 
ATOM   537  C CE1 . PHE A 1 111 ? -75.94509 -114.87689 -14.02902 1.000 66.33336  ? 110 PHE A CE1 1 
ATOM   538  C CE2 . PHE A 1 111 ? -76.72930 -113.68154 -15.94558 1.000 75.83733  ? 110 PHE A CE2 1 
ATOM   539  C CZ  . PHE A 1 111 ? -76.72434 -114.82344 -15.16825 1.000 75.18452  ? 110 PHE A CZ  1 
ATOM   540  N N   . GLU A 1 112 ? -72.24121 -109.18215 -14.65029 1.000 54.54230  ? 111 GLU A N   1 
ATOM   541  C CA  . GLU A 1 112 ? -71.67553 -107.94217 -14.14454 1.000 59.29198  ? 111 GLU A CA  1 
ATOM   542  C C   . GLU A 1 112 ? -72.79173 -107.03736 -13.64249 1.000 55.81162  ? 111 GLU A C   1 
ATOM   543  O O   . GLU A 1 112 ? -73.83327 -106.89963 -14.29081 1.000 55.99839  ? 111 GLU A O   1 
ATOM   544  C CB  . GLU A 1 112 ? -70.85633 -107.21675 -15.21430 1.000 58.30094  ? 111 GLU A CB  1 
ATOM   545  C CG  . GLU A 1 112 ? -70.13986 -105.98958 -14.67412 1.000 60.47439  ? 111 GLU A CG  1 
ATOM   546  C CD  . GLU A 1 112 ? -69.22412 -105.34226 -15.68875 1.000 67.06877  ? 111 GLU A CD  1 
ATOM   547  O OE1 . GLU A 1 112 ? -69.17309 -105.82334 -16.84037 1.000 67.09996  ? 111 GLU A OE1 1 
ATOM   548  O OE2 . GLU A 1 112 ? -68.55076 -104.35295 -15.32853 1.000 69.74316  ? 111 GLU A OE2 1 
ATOM   549  N N   . ARG A 1 113 ? -72.56815 -106.43584 -12.47911 1.000 58.28710  ? 112 ARG A N   1 
ATOM   550  C CA  . ARG A 1 113 ? -73.48891 -105.48938 -11.86674 1.000 58.87004  ? 112 ARG A CA  1 
ATOM   551  C C   . ARG A 1 113 ? -72.76320 -104.16053 -11.69175 1.000 60.96556  ? 112 ARG A C   1 
ATOM   552  O O   . ARG A 1 113 ? -71.53442 -104.11500 -11.83267 1.000 59.66949  ? 112 ARG A O   1 
ATOM   553  C CB  . ARG A 1 113 ? -74.00268 -106.03133 -10.52995 1.000 59.32645  ? 112 ARG A CB  1 
ATOM   554  C CG  . ARG A 1 113 ? -75.15035 -107.01814 -10.66542 1.000 52.13406  ? 112 ARG A CG  1 
ATOM   555  C CD  . ARG A 1 113 ? -75.58739 -107.54282 -9.30976  1.000 56.39050  ? 112 ARG A CD  1 
ATOM   556  N NE  . ARG A 1 113 ? -76.86738 -108.23571 -9.38569  1.000 58.66322  ? 112 ARG A NE  1 
ATOM   557  C CZ  . ARG A 1 113 ? -77.49021 -108.77476 -8.34683  1.000 56.43004  ? 112 ARG A CZ  1 
ATOM   558  N NH1 . ARG A 1 113 ? -76.96399 -108.74368 -7.13320  1.000 51.67603  ? 112 ARG A NH1 1 
ATOM   559  N NH2 . ARG A 1 113 ? -78.67084 -109.35924 -8.53013  1.000 56.30985  ? 112 ARG A NH2 1 
ATOM   560  N N   . PRO A 1 114 ? -73.47450 -103.06112 -11.40865 1.000 65.38824  ? 113 PRO A N   1 
ATOM   561  C CA  . PRO A 1 114 ? -72.78850 -101.76349 -11.27095 1.000 68.27836  ? 113 PRO A CA  1 
ATOM   562  C C   . PRO A 1 114 ? -71.60010 -101.77089 -10.32136 1.000 68.28101  ? 113 PRO A C   1 
ATOM   563  O O   . PRO A 1 114 ? -70.57728 -101.14469 -10.62369 1.000 69.43136  ? 113 PRO A O   1 
ATOM   564  C CB  . PRO A 1 114 ? -73.90882 -100.84448 -10.76848 1.000 72.48105  ? 113 PRO A CB  1 
ATOM   565  C CG  . PRO A 1 114 ? -75.13684 -101.40952 -11.38560 1.000 69.73088  ? 113 PRO A CG  1 
ATOM   566  C CD  . PRO A 1 114 ? -74.94197 -102.90457 -11.39629 1.000 65.86055  ? 113 PRO A CD  1 
ATOM   567  N N   . ASP A 1 115 ? -71.69263 -102.47093 -9.18760  1.000 67.80562  ? 114 ASP A N   1 
ATOM   568  C CA  . ASP A 1 115 ? -70.63591 -102.42696 -8.18306  1.000 68.35824  ? 114 ASP A CA  1 
ATOM   569  C C   . ASP A 1 115 ? -70.15141 -103.81573 -7.77797  1.000 65.55632  ? 114 ASP A C   1 
ATOM   570  O O   . ASP A 1 115 ? -69.47021 -103.94960 -6.75546  1.000 61.94523  ? 114 ASP A O   1 
ATOM   571  C CB  . ASP A 1 115 ? -71.10751 -101.65585 -6.94707  1.000 76.74818  ? 114 ASP A CB  1 
ATOM   572  C CG  . ASP A 1 115 ? -71.42060 -100.20256 -7.25146  1.000 81.61308  ? 114 ASP A CG  1 
ATOM   573  O OD1 . ASP A 1 115 ? -70.56551 -99.52396  -7.85861  1.000 84.04848  ? 114 ASP A OD1 1 
ATOM   574  O OD2 . ASP A 1 115 ? -72.52491 -99.74247  -6.89270  1.000 80.43407  ? 114 ASP A OD2 1 
ATOM   575  N N   . SER A 1 116 ? -70.46993 -104.84955 -8.55454  1.000 63.12833  ? 115 SER A N   1 
ATOM   576  C CA  . SER A 1 116 ? -70.10575 -106.20284 -8.15974  1.000 57.23150  ? 115 SER A CA  1 
ATOM   577  C C   . SER A 1 116 ? -70.15521 -107.12710 -9.36596  1.000 55.43610  ? 115 SER A C   1 
ATOM   578  O O   . SER A 1 116 ? -70.74327 -106.80461 -10.40050 1.000 53.35475  ? 115 SER A O   1 
ATOM   579  C CB  . SER A 1 116 ? -71.03314 -106.73219 -7.06103  1.000 53.99092  ? 115 SER A CB  1 
ATOM   580  O OG  . SER A 1 116 ? -72.34539 -106.91622 -7.56174  1.000 52.27914  ? 115 SER A OG  1 
ATOM   581  N N   . PHE A 1 117 ? -69.52305 -108.28564 -9.20931  1.000 51.63614  ? 116 PHE A N   1 
ATOM   582  C CA  . PHE A 1 117 ? -69.65075 -109.40067 -10.13399 1.000 50.06168  ? 116 PHE A CA  1 
ATOM   583  C C   . PHE A 1 117 ? -70.33765 -110.55837 -9.42308  1.000 52.11241  ? 116 PHE A C   1 
ATOM   584  O O   . PHE A 1 117 ? -70.09090 -110.80627 -8.23844  1.000 46.76611  ? 116 PHE A O   1 
ATOM   585  C CB  . PHE A 1 117 ? -68.28492 -109.84799 -10.66259 1.000 50.19927  ? 116 PHE A CB  1 
ATOM   586  C CG  . PHE A 1 117 ? -67.74192 -108.97572 -11.75808 1.000 52.29239  ? 116 PHE A CG  1 
ATOM   587  C CD1 . PHE A 1 117 ? -67.00202 -107.84291 -11.46121 1.000 53.80225  ? 116 PHE A CD1 1 
ATOM   588  C CD2 . PHE A 1 117 ? -67.96789 -109.29353 -13.08747 1.000 54.46312  ? 116 PHE A CD2 1 
ATOM   589  C CE1 . PHE A 1 117 ? -66.50066 -107.04172 -12.47057 1.000 60.58628  ? 116 PHE A CE1 1 
ATOM   590  C CE2 . PHE A 1 117 ? -67.46875 -108.49591 -14.10252 1.000 57.11689  ? 116 PHE A CE2 1 
ATOM   591  C CZ  . PHE A 1 117 ? -66.73535 -107.36893 -13.79312 1.000 56.51723  ? 116 PHE A CZ  1 
ATOM   592  N N   . VAL A 1 118 ? -71.20423 -111.25915 -10.14633 1.000 45.32414  ? 117 VAL A N   1 
ATOM   593  C CA  . VAL A 1 118 ? -71.92996 -112.41095 -9.62443  1.000 45.90114  ? 117 VAL A CA  1 
ATOM   594  C C   . VAL A 1 118 ? -71.45623 -113.64728 -10.37388 1.000 50.02736  ? 117 VAL A C   1 
ATOM   595  O O   . VAL A 1 118 ? -71.49181 -113.68155 -11.60978 1.000 47.42539  ? 117 VAL A O   1 
ATOM   596  C CB  . VAL A 1 118 ? -73.45152 -112.22953 -9.76315  1.000 49.25540  ? 117 VAL A CB  1 
ATOM   597  C CG1 . VAL A 1 118 ? -74.17835 -113.44175 -9.21477  1.000 50.17106  ? 117 VAL A CG1 1 
ATOM   598  C CG2 . VAL A 1 118 ? -73.90359 -110.96115 -9.05218  1.000 46.45414  ? 117 VAL A CG2 1 
ATOM   599  N N   . LEU A 1 119 ? -71.01002 -114.65608 -9.63074  1.000 44.42971  ? 118 LEU A N   1 
ATOM   600  C CA  . LEU A 1 119 ? -70.48135 -115.88893 -10.20180 1.000 44.88620  ? 118 LEU A CA  1 
ATOM   601  C C   . LEU A 1 119 ? -71.43308 -117.03924 -9.90670  1.000 47.08488  ? 118 LEU A C   1 
ATOM   602  O O   . LEU A 1 119 ? -71.78699 -117.27598 -8.74639  1.000 44.47179  ? 118 LEU A O   1 
ATOM   603  C CB  . LEU A 1 119 ? -69.09046 -116.20371 -9.64449  1.000 43.39833  ? 118 LEU A CB  1 
ATOM   604  C CG  . LEU A 1 119 ? -67.87316 -115.55779 -10.31148 1.000 48.72976  ? 118 LEU A CG  1 
ATOM   605  C CD1 . LEU A 1 119 ? -67.95767 -114.04124 -10.29701 1.000 46.11811  ? 118 LEU A CD1 1 
ATOM   606  C CD2 . LEU A 1 119 ? -66.59882 -116.02729 -9.62899  1.000 46.48248  ? 118 LEU A CD2 1 
ATOM   607  N N   . ILE A 1 120 ? -71.83721 -117.75221 -10.95190 1.000 43.99725  ? 119 ILE A N   1 
ATOM   608  C CA  . ILE A 1 120 ? -72.72917 -118.89840 -10.82916 1.000 46.79154  ? 119 ILE A CA  1 
ATOM   609  C C   . ILE A 1 120 ? -71.86835 -120.15438 -10.84369 1.000 46.70970  ? 119 ILE A C   1 
ATOM   610  O O   . ILE A 1 120 ? -71.30430 -120.52454 -11.87933 1.000 44.97010  ? 119 ILE A O   1 
ATOM   611  C CB  . ILE A 1 120 ? -73.77768 -118.92845 -11.94821 1.000 51.65587  ? 119 ILE A CB  1 
ATOM   612  C CG1 . ILE A 1 120 ? -74.54665 -117.60522 -12.00356 1.000 53.33603  ? 119 ILE A CG1 1 
ATOM   613  C CG2 . ILE A 1 120 ? -74.72969 -120.09988 -11.74438 1.000 52.51909  ? 119 ILE A CG2 1 
ATOM   614  C CD1 . ILE A 1 120 ? -75.27828 -117.26246 -10.72366 1.000 50.63878  ? 119 ILE A CD1 1 
ATOM   615  N N   . LEU A 1 121 ? -71.77150 -120.81551 -9.69670  1.000 39.85714  ? 120 LEU A N   1 
ATOM   616  C CA  . LEU A 1 121 ? -70.94460 -121.99941 -9.53401  1.000 46.59850  ? 120 LEU A CA  1 
ATOM   617  C C   . LEU A 1 121 ? -71.82327 -123.22485 -9.33014  1.000 50.64479  ? 120 LEU A C   1 
ATOM   618  O O   . LEU A 1 121 ? -72.93662 -123.12840 -8.80814  1.000 50.09364  ? 120 LEU A O   1 
ATOM   619  C CB  . LEU A 1 121 ? -69.99539 -121.84469 -8.34035  1.000 42.23473  ? 120 LEU A CB  1 
ATOM   620  C CG  . LEU A 1 121 ? -69.08614 -120.61571 -8.34137  1.000 43.19705  ? 120 LEU A CG  1 
ATOM   621  C CD1 . LEU A 1 121 ? -68.45859 -120.41566 -6.97393  1.000 45.30530  ? 120 LEU A CD1 1 
ATOM   622  C CD2 . LEU A 1 121 ? -68.01037 -120.75064 -9.40852  1.000 41.69148  ? 120 LEU A CD2 1 
ATOM   623  N N   . GLU A 1 122 ? -71.31392 -124.37992 -9.75085  1.000 51.76180  ? 121 GLU A N   1 
ATOM   624  C CA  . GLU A 1 122 ? -71.97062 -125.63685 -9.42407  1.000 58.84951  ? 121 GLU A CA  1 
ATOM   625  C C   . GLU A 1 122 ? -72.00052 -125.82542 -7.91152  1.000 60.11698  ? 121 GLU A C   1 
ATOM   626  O O   . GLU A 1 122 ? -71.17011 -125.28162 -7.17905  1.000 64.00335  ? 121 GLU A O   1 
ATOM   627  C CB  . GLU A 1 122 ? -71.24352 -126.80959 -10.08215 1.000 59.99365  ? 121 GLU A CB  1 
ATOM   628  C CG  . GLU A 1 122 ? -69.87911 -127.09618 -9.46752  1.000 64.17726  ? 121 GLU A CG  1 
ATOM   629  C CD  . GLU A 1 122 ? -69.20193 -128.31377 -10.06645 1.000 66.95978  ? 121 GLU A CD  1 
ATOM   630  O OE1 . GLU A 1 122 ? -69.89919 -129.13855 -10.69756 1.000 72.22960  ? 121 GLU A OE1 1 
ATOM   631  O OE2 . GLU A 1 122 ? -67.96834 -128.43964 -9.90751  1.000 60.23873  ? 121 GLU A OE2 1 
ATOM   632  N N   . ARG A 1 123 ? -72.97612 -126.59677 -7.43676  1.000 57.47218  ? 122 ARG A N   1 
ATOM   633  C CA  . ARG A 1 123 ? -73.11874 -126.86690 -6.00719  1.000 63.52223  ? 122 ARG A CA  1 
ATOM   634  C C   . ARG A 1 123 ? -73.40506 -128.34702 -5.79749  1.000 62.51454  ? 122 ARG A C   1 
ATOM   635  O O   . ARG A 1 123 ? -74.55580 -128.79198 -5.93976  1.000 59.97517  ? 122 ARG A O   1 
ATOM   636  C CB  . ARG A 1 123 ? -74.21125 -126.00695 -5.37613  1.000 62.09035  ? 122 ARG A CB  1 
ATOM   637  C CG  . ARG A 1 123 ? -74.42562 -126.28078 -3.89295  1.000 60.93257  ? 122 ARG A CG  1 
ATOM   638  C CD  . ARG A 1 123 ? -75.32808 -125.23668 -3.25361  1.000 62.14235  ? 122 ARG A CD  1 
ATOM   639  N NE  . ARG A 1 123 ? -76.63269 -125.16329 -3.89970  1.000 62.38909  ? 122 ARG A NE  1 
ATOM   640  C CZ  . ARG A 1 123 ? -77.70142 -125.84519 -3.51075  1.000 66.62162  ? 122 ARG A CZ  1 
ATOM   641  N NH1 . ARG A 1 123 ? -77.65771 -126.66702 -2.47481  1.000 67.99634  ? 122 ARG A NH1 1 
ATOM   642  N NH2 . ARG A 1 123 ? -78.84279 -125.69810 -4.17740  1.000 65.77802  ? 122 ARG A NH2 1 
ATOM   643  N N   . PRO A 1 124 ? -72.38954 -129.13975 -5.47049  1.000 62.32141  ? 123 PRO A N   1 
ATOM   644  C CA  . PRO A 1 124 ? -72.64369 -130.52424 -5.06653  1.000 60.35103  ? 123 PRO A CA  1 
ATOM   645  C C   . PRO A 1 124 ? -73.34810 -130.57000 -3.72119  1.000 56.46847  ? 123 PRO A C   1 
ATOM   646  O O   . PRO A 1 124 ? -73.21308 -129.66781 -2.89161  1.000 57.77402  ? 123 PRO A O   1 
ATOM   647  C CB  . PRO A 1 124 ? -71.24021 -131.13600 -4.98711  1.000 62.22317  ? 123 PRO A CB  1 
ATOM   648  C CG  . PRO A 1 124 ? -70.33175 -129.96768 -4.76320  1.000 60.21003  ? 123 PRO A CG  1 
ATOM   649  C CD  . PRO A 1 124 ? -70.95219 -128.81973 -5.50227  1.000 60.37606  ? 123 PRO A CD  1 
ATOM   650  N N   . GLU A 1 125 ? -74.12306 -131.63532 -3.51689  1.000 56.34742  ? 124 GLU A N   1 
ATOM   651  C CA  . GLU A 1 125 ? -74.88419 -131.82880 -2.29108  1.000 55.78356  ? 124 GLU A CA  1 
ATOM   652  C C   . GLU A 1 125 ? -74.89311 -133.30976 -1.93970  1.000 58.73780  ? 124 GLU A C   1 
ATOM   653  O O   . GLU A 1 125 ? -75.03879 -134.15734 -2.83319  1.000 60.50695  ? 124 GLU A O   1 
ATOM   654  C CB  . GLU A 1 125 ? -76.33117 -131.32968 -2.42519  1.000 56.59593  ? 124 GLU A CB  1 
ATOM   655  C CG  . GLU A 1 125 ? -76.49203 -129.81889 -2.51996  1.000 61.13290  ? 124 GLU A CG  1 
ATOM   656  C CD  . GLU A 1 125 ? -76.18439 -129.10811 -1.21543  1.000 64.69306  ? 124 GLU A CD  1 
ATOM   657  O OE1 . GLU A 1 125 ? -75.01794 -128.71041 -1.00751  1.000 68.30029  ? 124 GLU A OE1 1 
ATOM   658  N N   . PRO A 1 126 ? -74.72536 -133.65510 -0.65754  1.000 57.70906  ? 125 PRO A N   1 
ATOM   659  C CA  . PRO A 1 126 ? -74.41098 -132.77745 0.47658   1.000 52.62545  ? 125 PRO A CA  1 
ATOM   660  C C   . PRO A 1 126 ? -72.90830 -132.54304 0.56839   1.000 52.64829  ? 125 PRO A C   1 
ATOM   661  O O   . PRO A 1 126 ? -72.13242 -133.39602 0.14664   1.000 49.76537  ? 125 PRO A O   1 
ATOM   662  C CB  . PRO A 1 126 ? -74.95485 -133.56698 1.67013   1.000 55.19978  ? 125 PRO A CB  1 
ATOM   663  C CG  . PRO A 1 126 ? -74.71794 -134.99806 1.27578   1.000 55.19307  ? 125 PRO A CG  1 
ATOM   664  C CD  . PRO A 1 126 ? -74.95522 -135.04396 -0.21936  1.000 56.14638  ? 125 PRO A CD  1 
ATOM   665  N N   . VAL A 1 127 ? -72.45634 -131.40952 1.10731   1.000 50.09761  ? 126 VAL A N   1 
ATOM   666  C CA  . VAL A 1 127 ? -71.03492 -131.10620 1.18710   1.000 48.28997  ? 126 VAL A CA  1 
ATOM   667  C C   . VAL A 1 127 ? -70.68007 -130.63514 2.58979   1.000 47.60418  ? 126 VAL A C   1 
ATOM   668  O O   . VAL A 1 127 ? -71.52532 -130.16264 3.35251   1.000 45.20414  ? 126 VAL A O   1 
ATOM   669  C CB  . VAL A 1 127 ? -70.59754 -130.04271 0.15464   1.000 51.69971  ? 126 VAL A CB  1 
ATOM   670  C CG1 . VAL A 1 127 ? -70.61797 -130.61945 -1.25027  1.000 49.63400  ? 126 VAL A CG1 1 
ATOM   671  C CG2 . VAL A 1 127 ? -71.48726 -128.81230 0.25415   1.000 51.45489  ? 126 VAL A CG2 1 
ATOM   672  N N   . GLN A 1 128 ? -69.40034 -130.78774 2.91808   1.000 44.43743  ? 127 GLN A N   1 
ATOM   673  C CA  . GLN A 1 128 ? -68.77610 -130.15585 4.07057   1.000 41.22979  ? 127 GLN A CA  1 
ATOM   674  C C   . GLN A 1 128 ? -67.35050 -129.83145 3.65855   1.000 42.50744  ? 127 GLN A C   1 
ATOM   675  O O   . GLN A 1 128 ? -66.71104 -130.63369 2.97224   1.000 39.43383  ? 127 GLN A O   1 
ATOM   676  C CB  . GLN A 1 128 ? -68.79462 -131.06683 5.30874   1.000 43.90373  ? 127 GLN A CB  1 
ATOM   677  C CG  . GLN A 1 128 ? -68.26524 -130.41866 6.59160   1.000 39.83443  ? 127 GLN A CG  1 
ATOM   678  C CD  . GLN A 1 128 ? -68.21118 -131.39015 7.76519   1.000 47.29963  ? 127 GLN A CD  1 
ATOM   679  O OE1 . GLN A 1 128 ? -67.88657 -132.56564 7.59798   1.000 45.62657  ? 127 GLN A OE1 1 
ATOM   680  N NE2 . GLN A 1 128 ? -68.53531 -130.90007 8.95878   1.000 45.82751  ? 127 GLN A NE2 1 
ATOM   681  N N   . ASP A 1 129 ? -66.86506 -128.65129 4.03671   1.000 38.25978  ? 128 ASP A N   1 
ATOM   682  C CA  . ASP A 1 129 ? -65.49561 -128.33090 3.67336   1.000 38.00502  ? 128 ASP A CA  1 
ATOM   683  C C   . ASP A 1 129 ? -64.52972 -129.13947 4.53620   1.000 38.31659  ? 128 ASP A C   1 
ATOM   684  O O   . ASP A 1 129 ? -64.87954 -129.63840 5.61102   1.000 39.40481  ? 128 ASP A O   1 
ATOM   685  C CB  . ASP A 1 129 ? -65.22323 -126.82301 3.77865   1.000 41.23025  ? 128 ASP A CB  1 
ATOM   686  C CG  . ASP A 1 129 ? -65.23510 -126.30248 5.20900   1.000 38.00212  ? 128 ASP A CG  1 
ATOM   687  O OD1 . ASP A 1 129 ? -64.44297 -126.78065 6.04681   1.000 44.25178  ? 128 ASP A OD1 1 
ATOM   688  O OD2 . ASP A 1 129 ? -66.01926 -125.37363 5.48498   1.000 50.61296  ? 128 ASP A OD2 1 
ATOM   689  N N   . LEU A 1 130 ? -63.29736 -129.27392 4.04195   1.000 35.97790  ? 129 LEU A N   1 
ATOM   690  C CA  . LEU A 1 130 ? -62.33748 -130.15179 4.69775   1.000 37.00899  ? 129 LEU A CA  1 
ATOM   691  C C   . LEU A 1 130 ? -61.90290 -129.60807 6.05496   1.000 35.10826  ? 129 LEU A C   1 
ATOM   692  O O   . LEU A 1 130 ? -61.51522 -130.38864 6.93247   1.000 37.76936  ? 129 LEU A O   1 
ATOM   693  C CB  . LEU A 1 130 ? -61.13236 -130.37682 3.78431   1.000 33.47220  ? 129 LEU A CB  1 
ATOM   694  C CG  . LEU A 1 130 ? -60.01665 -131.30897 4.26758   1.000 35.65267  ? 129 LEU A CG  1 
ATOM   695  C CD1 . LEU A 1 130 ? -60.56398 -132.67738 4.65656   1.000 32.01329  ? 129 LEU A CD1 1 
ATOM   696  C CD2 . LEU A 1 130 ? -58.94162 -131.44684 3.18590   1.000 34.04467  ? 129 LEU A CD2 1 
ATOM   697  N N   . PHE A 1 131 ? -61.96754 -128.28849 6.25737   1.000 35.85919  ? 130 PHE A N   1 
ATOM   698  C CA  . PHE A 1 131 ? -61.63905 -127.73800 7.57097   1.000 38.39077  ? 130 PHE A CA  1 
ATOM   699  C C   . PHE A 1 131 ? -62.61916 -128.23028 8.63119   1.000 39.52562  ? 130 PHE A C   1 
ATOM   700  O O   . PHE A 1 131 ? -62.20925 -128.74387 9.67848   1.000 40.68511  ? 130 PHE A O   1 
ATOM   701  C CB  . PHE A 1 131 ? -61.61714 -126.20648 7.53402   1.000 36.21141  ? 130 PHE A CB  1 
ATOM   702  C CG  . PHE A 1 131 ? -61.25872 -125.57782 8.86281   1.000 38.15854  ? 130 PHE A CG  1 
ATOM   703  C CD1 . PHE A 1 131 ? -62.23680 -125.31504 9.81228   1.000 39.67896  ? 130 PHE A CD1 1 
ATOM   704  C CD2 . PHE A 1 131 ? -59.94188 -125.26729 9.16554   1.000 39.07825  ? 130 PHE A CD2 1 
ATOM   705  C CE1 . PHE A 1 131 ? -61.90958 -124.75564 11.04119  1.000 43.68686  ? 130 PHE A CE1 1 
ATOM   706  C CE2 . PHE A 1 131 ? -59.60642 -124.70619 10.38899  1.000 43.89262  ? 130 PHE A CE2 1 
ATOM   707  C CZ  . PHE A 1 131 ? -60.59389 -124.44767 11.32565  1.000 40.73495  ? 130 PHE A CZ  1 
ATOM   708  N N   . ASP A 1 132 ? -63.92333 -128.06439 8.38490   1.000 39.86598  ? 131 ASP A N   1 
ATOM   709  C CA  . ASP A 1 132 ? -64.91945 -128.53256 9.34737   1.000 41.85918  ? 131 ASP A CA  1 
ATOM   710  C C   . ASP A 1 132 ? -64.85098 -130.04264 9.51900   1.000 41.15326  ? 131 ASP A C   1 
ATOM   711  O O   . ASP A 1 132 ? -65.06429 -130.56089 10.62151  1.000 44.86622  ? 131 ASP A O   1 
ATOM   712  C CB  . ASP A 1 132 ? -66.32575 -128.12262 8.90844   1.000 42.11059  ? 131 ASP A CB  1 
ATOM   713  C CG  . ASP A 1 132 ? -66.56622 -126.63379 9.02659   1.000 46.34108  ? 131 ASP A CG  1 
ATOM   714  O OD1 . ASP A 1 132 ? -65.87267 -125.97272 9.82855   1.000 46.66286  ? 131 ASP A OD1 1 
ATOM   715  O OD2 . ASP A 1 132 ? -67.45691 -126.12598 8.31649   1.000 51.95573  ? 131 ASP A OD2 1 
ATOM   716  N N   . PHE A 1 133 ? -64.56910 -130.76343 8.43201   1.000 38.79862  ? 132 PHE A N   1 
ATOM   717  C CA  . PHE A 1 133 ? -64.46511 -132.21747 8.49450   1.000 38.45703  ? 132 PHE A CA  1 
ATOM   718  C C   . PHE A 1 133 ? -63.35829 -132.64145 9.45153   1.000 40.24889  ? 132 PHE A C   1 
ATOM   719  O O   . PHE A 1 133 ? -63.55989 -133.50741 10.30888  1.000 39.35753  ? 132 PHE A O   1 
ATOM   720  C CB  . PHE A 1 133 ? -64.21762 -132.77097 7.08646   1.000 39.06700  ? 132 PHE A CB  1 
ATOM   721  C CG  . PHE A 1 133 ? -64.28812 -134.27165 6.98935   1.000 40.53226  ? 132 PHE A CG  1 
ATOM   722  C CD1 . PHE A 1 133 ? -65.50020 -134.90909 6.76688   1.000 42.27006  ? 132 PHE A CD1 1 
ATOM   723  C CD2 . PHE A 1 133 ? -63.13939 -135.04315 7.09359   1.000 40.83969  ? 132 PHE A CD2 1 
ATOM   724  C CE1 . PHE A 1 133 ? -65.56840 -136.28744 6.66420   1.000 40.27844  ? 132 PHE A CE1 1 
ATOM   725  C CE2 . PHE A 1 133 ? -63.20115 -136.42342 6.99448   1.000 44.02156  ? 132 PHE A CE2 1 
ATOM   726  C CZ  . PHE A 1 133 ? -64.41799 -137.04600 6.77874   1.000 43.39284  ? 132 PHE A CZ  1 
ATOM   727  N N   . ILE A 1 134 ? -62.18180 -132.02378 9.33080   1.000 37.63799  ? 133 ILE A N   1 
ATOM   728  C CA  . ILE A 1 134 ? -61.06419 -132.37573 10.20248  1.000 40.76596  ? 133 ILE A CA  1 
ATOM   729  C C   . ILE A 1 134 ? -61.33275 -131.92326 11.63365  1.000 41.72431  ? 133 ILE A C   1 
ATOM   730  O O   . ILE A 1 134 ? -60.97061 -132.61313 12.59569  1.000 43.00804  ? 133 ILE A O   1 
ATOM   731  C CB  . ILE A 1 134 ? -59.75466 -131.78433 9.64702   1.000 35.59777  ? 133 ILE A CB  1 
ATOM   732  C CG1 . ILE A 1 134 ? -59.38111 -132.47920 8.33444   1.000 33.89040  ? 133 ILE A CG1 1 
ATOM   733  C CG2 . ILE A 1 134 ? -58.62699 -131.91497 10.66170  1.000 39.16230  ? 133 ILE A CG2 1 
ATOM   734  C CD1 . ILE A 1 134 ? -58.25074 -131.79937 7.57522   1.000 34.16000  ? 133 ILE A CD1 1 
ATOM   735  N N   . THR A 1 135 ? -61.97618 -130.76541 11.80230  1.000 42.55237  ? 134 THR A N   1 
ATOM   736  C CA  . THR A 1 135 ? -62.31829 -130.31012 13.14672  1.000 41.00611  ? 134 THR A CA  1 
ATOM   737  C C   . THR A 1 135 ? -63.21727 -131.31448 13.85689  1.000 44.33912  ? 134 THR A C   1 
ATOM   738  O O   . THR A 1 135 ? -63.02226 -131.60352 15.04342  1.000 45.22233  ? 134 THR A O   1 
ATOM   739  C CB  . THR A 1 135 ? -62.99501 -128.93903 13.09000  1.000 39.10765  ? 134 THR A CB  1 
ATOM   740  O OG1 . THR A 1 135 ? -62.08258 -127.97434 12.55286  1.000 38.63286  ? 134 THR A OG1 1 
ATOM   741  C CG2 . THR A 1 135 ? -63.42758 -128.49798 14.48564  1.000 46.73191  ? 134 THR A CG2 1 
ATOM   742  N N   . GLU A 1 136 ? -64.19472 -131.87564 13.14351  1.000 43.59320  ? 135 GLU A N   1 
ATOM   743  C CA  . GLU A 1 136 ? -65.15856 -132.75943 13.79216  1.000 48.64823  ? 135 GLU A CA  1 
ATOM   744  C C   . GLU A 1 136 ? -64.61348 -134.17181 13.97146  1.000 46.04912  ? 135 GLU A C   1 
ATOM   745  O O   . GLU A 1 136 ? -64.90050 -134.82308 14.98027  1.000 43.92701  ? 135 GLU A O   1 
ATOM   746  C CB  . GLU A 1 136 ? -66.46431 -132.78872 12.99708  1.000 46.76263  ? 135 GLU A CB  1 
ATOM   747  C CG  . GLU A 1 136 ? -67.21862 -131.46740 13.01780  1.000 55.80042  ? 135 GLU A CG  1 
ATOM   748  C CD  . GLU A 1 136 ? -68.48781 -131.50255 12.19176  1.000 61.72637  ? 135 GLU A CD  1 
ATOM   749  O OE1 . GLU A 1 136 ? -68.85158 -132.59359 11.70248  1.000 63.49832  ? 135 GLU A OE1 1 
ATOM   750  O OE2 . GLU A 1 136 ? -69.12014 -130.43709 12.02805  1.000 67.15424  ? 135 GLU A OE2 1 
ATOM   751  N N   . ARG A 1 137 ? -63.82989 -134.66890 13.01780  1.000 44.65923  ? 136 ARG A N   1 
ATOM   752  C CA  . ARG A 1 137 ? -63.35629 -136.04333 13.09167  1.000 46.34744  ? 136 ARG A CA  1 
ATOM   753  C C   . ARG A 1 137 ? -61.98091 -136.17305 13.73339  1.000 43.39736  ? 136 ARG A C   1 
ATOM   754  O O   . ARG A 1 137 ? -61.59397 -137.28578 14.10733  1.000 45.31542  ? 136 ARG A O   1 
ATOM   755  C CB  . ARG A 1 137 ? -63.33569 -136.66732 11.68970  1.000 47.53934  ? 136 ARG A CB  1 
ATOM   756  C CG  . ARG A 1 137 ? -64.57469 -136.34102 10.85802  1.000 56.26340  ? 136 ARG A CG  1 
ATOM   757  C CD  . ARG A 1 137 ? -65.55127 -137.50271 10.74704  1.000 61.17158  ? 136 ARG A CD  1 
ATOM   758  N NE  . ARG A 1 137 ? -64.94523 -138.65272 10.08804  1.000 62.47663  ? 136 ARG A NE  1 
ATOM   759  C CZ  . ARG A 1 137 ? -65.56618 -139.43332 9.21381   1.000 57.05588  ? 136 ARG A CZ  1 
ATOM   760  N NH1 . ARG A 1 137 ? -66.80994 -139.19147 8.83005   1.000 51.53102  ? 136 ARG A NH1 1 
ATOM   761  N NH2 . ARG A 1 137 ? -64.91894 -140.47735 8.70350   1.000 54.09585  ? 136 ARG A NH2 1 
ATOM   762  N N   . GLY A 1 138 ? -61.24888 -135.07369 13.89425  1.000 44.41369  ? 137 GLY A N   1 
ATOM   763  C CA  . GLY A 1 138 ? -59.88571 -135.15832 14.37585  1.000 44.00525  ? 137 GLY A CA  1 
ATOM   764  C C   . GLY A 1 138 ? -58.94099 -135.57271 13.25990  1.000 44.62225  ? 137 GLY A C   1 
ATOM   765  O O   . GLY A 1 138 ? -59.24587 -135.45110 12.06923  1.000 40.53330  ? 137 GLY A O   1 
ATOM   766  N N   . ALA A 1 139 ? -57.77378 -136.07610 13.66058  1.000 42.74995  ? 138 ALA A N   1 
ATOM   767  C CA  . ALA A 1 139 ? -56.81022 -136.58847 12.69361  1.000 39.75490  ? 138 ALA A CA  1 
ATOM   768  C C   . ALA A 1 139 ? -57.41925 -137.73800 11.89948  1.000 41.21872  ? 138 ALA A C   1 
ATOM   769  O O   . ALA A 1 139 ? -58.05936 -138.62963 12.46415  1.000 40.13242  ? 138 ALA A O   1 
ATOM   770  C CB  . ALA A 1 139 ? -55.53790 -137.04923 13.40561  1.000 38.70236  ? 138 ALA A CB  1 
ATOM   771  N N   . LEU A 1 140 ? -57.22163 -137.71147 10.58413  1.000 34.90747  ? 139 LEU A N   1 
ATOM   772  C CA  . LEU A 1 140 ? -57.82128 -138.70291 9.70292   1.000 37.00252  ? 139 LEU A CA  1 
ATOM   773  C C   . LEU A 1 140 ? -56.94956 -139.94842 9.61538   1.000 36.66727  ? 139 LEU A C   1 
ATOM   774  O O   . LEU A 1 140 ? -55.71913 -139.86401 9.62646   1.000 38.67248  ? 139 LEU A O   1 
ATOM   775  C CB  . LEU A 1 140 ? -58.02473 -138.12035 8.29994   1.000 34.25342  ? 139 LEU A CB  1 
ATOM   776  C CG  . LEU A 1 140 ? -58.75276 -136.77527 8.19050   1.000 36.56458  ? 139 LEU A CG  1 
ATOM   777  C CD1 . LEU A 1 140 ? -58.90486 -136.34539 6.72472   1.000 34.68356  ? 139 LEU A CD1 1 
ATOM   778  C CD2 . LEU A 1 140 ? -60.10853 -136.83712 8.88061   1.000 39.51153  ? 139 LEU A CD2 1 
ATOM   779  N N   . GLN A 1 141 ? -57.59830 -141.10887 9.52875   1.000 36.37884  ? 140 GLN A N   1 
ATOM   780  C CA  . GLN A 1 141 ? -56.88875 -142.33553 9.19169   1.000 41.19761  ? 140 GLN A CA  1 
ATOM   781  C C   . GLN A 1 141 ? -56.11790 -142.14714 7.89162   1.000 37.79791  ? 140 GLN A C   1 
ATOM   782  O O   . GLN A 1 141 ? -56.58790 -141.47893 6.96615   1.000 36.74335  ? 140 GLN A O   1 
ATOM   783  C CB  . GLN A 1 141 ? -57.87065 -143.49943 9.04932   1.000 40.43516  ? 140 GLN A CB  1 
ATOM   784  C CG  . GLN A 1 141 ? -58.74718 -143.71996 10.26357  1.000 53.62866  ? 140 GLN A CG  1 
ATOM   785  C CD  . GLN A 1 141 ? -59.66977 -144.90911 10.10252  1.000 59.93775  ? 140 GLN A CD  1 
ATOM   786  O OE1 . GLN A 1 141 ? -59.60138 -145.63547 9.10747   1.000 57.95170  ? 140 GLN A OE1 1 
ATOM   787  N NE2 . GLN A 1 141 ? -60.54205 -145.11573 11.08351  1.000 63.75881  ? 140 GLN A NE2 1 
ATOM   788  N N   . GLU A 1 142 ? -54.92372 -142.74310 7.82455   1.000 34.36891  ? 141 GLU A N   1 
ATOM   789  C CA  . GLU A 1 142 ? -54.05437 -142.51396 6.67403   1.000 38.24295  ? 141 GLU A CA  1 
ATOM   790  C C   . GLU A 1 142 ? -54.68529 -143.00613 5.37628   1.000 37.03271  ? 141 GLU A C   1 
ATOM   791  O O   . GLU A 1 142 ? -54.43913 -142.42711 4.31371   1.000 38.36006  ? 141 GLU A O   1 
ATOM   792  C CB  . GLU A 1 142 ? -52.69312 -143.17418 6.90280   1.000 38.24469  ? 141 GLU A CB  1 
ATOM   793  C CG  . GLU A 1 142 ? -51.91989 -142.54922 8.05903   1.000 40.25689  ? 141 GLU A CG  1 
ATOM   794  C CD  . GLU A 1 142 ? -50.46589 -142.96811 8.11029   1.000 43.24937  ? 141 GLU A CD  1 
ATOM   795  O OE1 . GLU A 1 142 ? -49.94315 -143.48227 7.09764   1.000 39.03761  ? 141 GLU A OE1 1 
ATOM   796  O OE2 . GLU A 1 142 ? -49.83925 -142.77759 9.17398   1.000 43.40099  ? 141 GLU A OE2 1 
ATOM   797  N N   . GLU A 1 143 ? -55.50143 -144.06142 5.43846   1.000 36.68662  ? 142 GLU A N   1 
ATOM   798  C CA  . GLU A 1 143 ? -56.21467 -144.51326 4.24726   1.000 39.53494  ? 142 GLU A CA  1 
ATOM   799  C C   . GLU A 1 143 ? -57.12841 -143.41889 3.71059   1.000 38.60781  ? 142 GLU A C   1 
ATOM   800  O O   . GLU A 1 143 ? -57.20054 -143.19643 2.49602   1.000 36.59839  ? 142 GLU A O   1 
ATOM   801  C CB  . GLU A 1 143 ? -57.02057 -145.77568 4.56268   1.000 41.56089  ? 142 GLU A CB  1 
ATOM   802  C CG  . GLU A 1 143 ? -57.72946 -146.37526 3.35789   1.000 47.03068  ? 142 GLU A CG  1 
ATOM   803  C CD  . GLU A 1 143 ? -58.63814 -147.53738 3.72348   1.000 47.59504  ? 142 GLU A CD  1 
ATOM   804  O OE1 . GLU A 1 143 ? -59.66489 -147.30815 4.39641   1.000 47.52146  ? 142 GLU A OE1 1 
ATOM   805  O OE2 . GLU A 1 143 ? -58.32316 -148.68081 3.33655   1.000 50.72178  ? 142 GLU A OE2 1 
ATOM   806  N N   . LEU A 1 144 ? -57.83045 -142.72125 4.60622   1.000 37.83613  ? 143 LEU A N   1 
ATOM   807  C CA  . LEU A 1 144 ? -58.70950 -141.63472 4.18811   1.000 37.53555  ? 143 LEU A CA  1 
ATOM   808  C C   . LEU A 1 144 ? -57.90906 -140.41895 3.73723   1.000 38.07349  ? 143 LEU A C   1 
ATOM   809  O O   . LEU A 1 144 ? -58.24193 -139.78896 2.72641   1.000 35.61803  ? 143 LEU A O   1 
ATOM   810  C CB  . LEU A 1 144 ? -59.65387 -141.26428 5.33253   1.000 38.42836  ? 143 LEU A CB  1 
ATOM   811  C CG  . LEU A 1 144 ? -60.62526 -140.11045 5.09096   1.000 41.79741  ? 143 LEU A CG  1 
ATOM   812  C CD1 . LEU A 1 144 ? -61.49252 -140.40679 3.88347   1.000 37.05171  ? 143 LEU A CD1 1 
ATOM   813  C CD2 . LEU A 1 144 ? -61.48918 -139.86416 6.32488   1.000 41.05828  ? 143 LEU A CD2 1 
ATOM   814  N N   . ALA A 1 145 ? -56.85213 -140.07005 4.47602   1.000 36.78617  ? 144 ALA A N   1 
ATOM   815  C CA  . ALA A 1 145 ? -56.00748 -138.95416 4.06480   1.000 35.87433  ? 144 ALA A CA  1 
ATOM   816  C C   . ALA A 1 145 ? -55.33295 -139.22788 2.72660   1.000 37.30402  ? 144 ALA A C   1 
ATOM   817  O O   . ALA A 1 145 ? -55.14142 -138.30128 1.93292   1.000 33.13332  ? 144 ALA A O   1 
ATOM   818  C CB  . ALA A 1 145 ? -54.96129 -138.65522 5.13914   1.000 31.81319  ? 144 ALA A CB  1 
ATOM   819  N N   . ARG A 1 146 ? -54.97210 -140.48671 2.45624   1.000 37.39358  ? 145 ARG A N   1 
ATOM   820  C CA  . ARG A 1 146 ? -54.38140 -140.82957 1.16503   1.000 37.88133  ? 145 ARG A CA  1 
ATOM   821  C C   . ARG A 1 146 ? -55.35568 -140.55500 0.02595   1.000 36.46343  ? 145 ARG A C   1 
ATOM   822  O O   . ARG A 1 146 ? -54.98502 -139.96284 -0.99381  1.000 36.15533  ? 145 ARG A O   1 
ATOM   823  C CB  . ARG A 1 146 ? -53.94149 -142.29598 1.15308   1.000 35.74740  ? 145 ARG A CB  1 
ATOM   824  C CG  . ARG A 1 146 ? -53.46514 -142.79049 -0.21695  1.000 40.35738  ? 145 ARG A CG  1 
ATOM   825  C CD  . ARG A 1 146 ? -53.04530 -144.26172 -0.19403  1.000 39.90434  ? 145 ARG A CD  1 
ATOM   826  N NE  . ARG A 1 146 ? -51.98635 -144.50197 0.77883   1.000 43.80190  ? 145 ARG A NE  1 
ATOM   827  C CZ  . ARG A 1 146 ? -52.15133 -145.14547 1.92726   1.000 45.39550  ? 145 ARG A CZ  1 
ATOM   828  N NH1 . ARG A 1 146 ? -53.30938 -145.70135 2.25002   1.000 40.02390  ? 145 ARG A NH1 1 
ATOM   829  N NH2 . ARG A 1 146 ? -51.12738 -145.23791 2.77131   1.000 39.35972  ? 145 ARG A NH2 1 
ATOM   830  N N   . SER A 1 147 ? -56.61202 -140.97774 0.18548   1.000 37.14121  ? 146 SER A N   1 
ATOM   831  C CA  . SER A 1 147 ? -57.60756 -140.76474 -0.86022  1.000 35.78183  ? 146 SER A CA  1 
ATOM   832  C C   . SER A 1 147 ? -57.86219 -139.27882 -1.07806  1.000 38.76892  ? 146 SER A C   1 
ATOM   833  O O   . SER A 1 147 ? -57.89816 -138.80342 -2.22059  1.000 38.38565  ? 146 SER A O   1 
ATOM   834  C CB  . SER A 1 147 ? -58.90338 -141.49422 -0.50084  1.000 37.69819  ? 146 SER A CB  1 
ATOM   835  O OG  . SER A 1 147 ? -59.95711 -141.12246 -1.37170  1.000 39.03076  ? 146 SER A OG  1 
ATOM   836  N N   . PHE A 1 148 ? -58.03419 -138.52787 0.01427   1.000 31.70578  ? 147 PHE A N   1 
ATOM   837  C CA  . PHE A 1 148 ? -58.23409 -137.08490 -0.08807  1.000 34.63943  ? 147 PHE A CA  1 
ATOM   838  C C   . PHE A 1 148 ? -57.03283 -136.40761 -0.73783  1.000 35.66254  ? 147 PHE A C   1 
ATOM   839  O O   . PHE A 1 148 ? -57.18338 -135.61310 -1.67332  1.000 31.58484  ? 147 PHE A O   1 
ATOM   840  C CB  . PHE A 1 148 ? -58.48550 -136.48334 1.29740   1.000 32.70722  ? 147 PHE A CB  1 
ATOM   841  C CG  . PHE A 1 148 ? -59.87650 -136.70833 1.82973   1.000 37.17794  ? 147 PHE A CG  1 
ATOM   842  C CD1 . PHE A 1 148 ? -60.79284 -137.48083 1.13664   1.000 36.38417  ? 147 PHE A CD1 1 
ATOM   843  C CD2 . PHE A 1 148 ? -60.26659 -136.12916 3.02994   1.000 37.25695  ? 147 PHE A CD2 1 
ATOM   844  C CE1 . PHE A 1 148 ? -62.07216 -137.67664 1.63226   1.000 40.54775  ? 147 PHE A CE1 1 
ATOM   845  C CE2 . PHE A 1 148 ? -61.54114 -136.31811 3.52921   1.000 36.57450  ? 147 PHE A CE2 1 
ATOM   846  C CZ  . PHE A 1 148 ? -62.44564 -137.09501 2.83180   1.000 36.98491  ? 147 PHE A CZ  1 
ATOM   847  N N   . PHE A 1 149 ? -55.82855 -136.69949 -0.23691  1.000 32.27368  ? 148 PHE A N   1 
ATOM   848  C CA  . PHE A 1 149 ? -54.62703 -136.05813 -0.76069  1.000 32.67076  ? 148 PHE A CA  1 
ATOM   849  C C   . PHE A 1 149 ? -54.42773 -136.38212 -2.23563  1.000 33.20370  ? 148 PHE A C   1 
ATOM   850  O O   . PHE A 1 149 ? -54.05437 -135.50699 -3.02463  1.000 34.81997  ? 148 PHE A O   1 
ATOM   851  C CB  . PHE A 1 149 ? -53.40648 -136.48903 0.05522   1.000 32.73221  ? 148 PHE A CB  1 
ATOM   852  C CG  . PHE A 1 149 ? -52.18729 -135.64181 -0.17934  1.000 30.61343  ? 148 PHE A CG  1 
ATOM   853  C CD1 . PHE A 1 149 ? -52.21446 -134.28174 0.08084   1.000 32.87110  ? 148 PHE A CD1 1 
ATOM   854  C CD2 . PHE A 1 149 ? -51.00941 -136.20780 -0.63622  1.000 30.13251  ? 148 PHE A CD2 1 
ATOM   855  C CE1 . PHE A 1 149 ? -51.09290 -133.49646 -0.12487  1.000 32.65975  ? 148 PHE A CE1 1 
ATOM   856  C CE2 . PHE A 1 149 ? -49.88473 -135.43005 -0.84580  1.000 29.74454  ? 148 PHE A CE2 1 
ATOM   857  C CZ  . PHE A 1 149 ? -49.92741 -134.07163 -0.58816  1.000 30.09309  ? 148 PHE A CZ  1 
ATOM   858  N N   . TRP A 1 150 ? -54.68239 -137.63442 -2.62635  1.000 33.62252  ? 149 TRP A N   1 
ATOM   859  C CA  . TRP A 1 150 ? -54.55249 -138.02077 -4.02807  1.000 32.91929  ? 149 TRP A CA  1 
ATOM   860  C C   . TRP A 1 150 ? -55.47196 -137.19308 -4.91597  1.000 35.17187  ? 149 TRP A C   1 
ATOM   861  O O   . TRP A 1 150 ? -55.05355 -136.71064 -5.97540  1.000 31.49706  ? 149 TRP A O   1 
ATOM   862  C CB  . TRP A 1 150 ? -54.85112 -139.51286 -4.18838  1.000 33.88392  ? 149 TRP A CB  1 
ATOM   863  C CG  . TRP A 1 150 ? -54.71440 -140.01898 -5.59341  1.000 39.19332  ? 149 TRP A CG  1 
ATOM   864  C CD1 . TRP A 1 150 ? -55.68452 -140.04523 -6.55653  1.000 36.58104  ? 149 TRP A CD1 1 
ATOM   865  C CD2 . TRP A 1 150 ? -53.53997 -140.57861 -6.19268  1.000 34.26287  ? 149 TRP A CD2 1 
ATOM   866  N NE1 . TRP A 1 150 ? -55.18408 -140.58453 -7.71763  1.000 37.77522  ? 149 TRP A NE1 1 
ATOM   867  C CE2 . TRP A 1 150 ? -53.87020 -140.91885 -7.52145  1.000 39.91598  ? 149 TRP A CE2 1 
ATOM   868  C CE3 . TRP A 1 150 ? -52.24119 -140.82272 -5.73683  1.000 35.91511  ? 149 TRP A CE3 1 
ATOM   869  C CZ2 . TRP A 1 150 ? -52.95080 -141.49414 -8.39602  1.000 35.62108  ? 149 TRP A CZ2 1 
ATOM   870  C CZ3 . TRP A 1 150 ? -51.32815 -141.39298 -6.60805  1.000 38.72133  ? 149 TRP A CZ3 1 
ATOM   871  C CH2 . TRP A 1 150 ? -51.68799 -141.72057 -7.92451  1.000 35.28568  ? 149 TRP A CH2 1 
ATOM   872  N N   . GLN A 1 151 ? -56.72559 -137.00345 -4.49350  1.000 33.24881  ? 150 GLN A N   1 
ATOM   873  C CA  . GLN A 1 151 ? -57.66290 -136.23152 -5.30393  1.000 33.33290  ? 150 GLN A CA  1 
ATOM   874  C C   . GLN A 1 151 ? -57.26033 -134.76370 -5.37481  1.000 35.70377  ? 150 GLN A C   1 
ATOM   875  O O   . GLN A 1 151 ? -57.45091 -134.11515 -6.41040  1.000 35.10941  ? 150 GLN A O   1 
ATOM   876  C CB  . GLN A 1 151 ? -59.08371 -136.37086 -4.75678  1.000 33.86809  ? 150 GLN A CB  1 
ATOM   877  C CG  . GLN A 1 151 ? -59.69342 -137.75471 -4.93246  1.000 35.51732  ? 150 GLN A CG  1 
ATOM   878  C CD  . GLN A 1 151 ? -61.15982 -137.78910 -4.54456  1.000 37.21687  ? 150 GLN A CD  1 
ATOM   879  O OE1 . GLN A 1 151 ? -61.91032 -136.86261 -4.84218  1.000 36.84617  ? 150 GLN A OE1 1 
ATOM   880  N NE2 . GLN A 1 151 ? -61.57052 -138.85261 -3.86423  1.000 41.86135  ? 150 GLN A NE2 1 
ATOM   881  N N   . VAL A 1 152 ? -56.71088 -134.21708 -4.28607  1.000 32.43603  ? 151 VAL A N   1 
ATOM   882  C CA  . VAL A 1 152 ? -56.22391 -132.84017 -4.32819  1.000 31.73979  ? 151 VAL A CA  1 
ATOM   883  C C   . VAL A 1 152 ? -55.07707 -132.71884 -5.32235  1.000 31.00258  ? 151 VAL A C   1 
ATOM   884  O O   . VAL A 1 152 ? -54.99487 -131.74817 -6.08596  1.000 32.90396  ? 151 VAL A O   1 
ATOM   885  C CB  . VAL A 1 152 ? -55.80904 -132.36663 -2.92041  1.000 34.99400  ? 151 VAL A CB  1 
ATOM   886  C CG1 . VAL A 1 152 ? -55.13559 -131.00329 -2.99105  1.000 32.56277  ? 151 VAL A CG1 1 
ATOM   887  C CG2 . VAL A 1 152 ? -57.01972 -132.30656 -1.99943  1.000 31.00990  ? 151 VAL A CG2 1 
ATOM   888  N N   . LEU A 1 153 ? -54.18306 -133.70994 -5.33975  1.000 32.54859  ? 152 LEU A N   1 
ATOM   889  C CA  . LEU A 1 153 ? -53.07938 -133.69803 -6.29472  1.000 33.90556  ? 152 LEU A CA  1 
ATOM   890  C C   . LEU A 1 153 ? -53.58747 -133.73435 -7.73077  1.000 32.95707  ? 152 LEU A C   1 
ATOM   891  O O   . LEU A 1 153 ? -53.08628 -133.00104 -8.59126  1.000 33.64481  ? 152 LEU A O   1 
ATOM   892  C CB  . LEU A 1 153 ? -52.14169 -134.87424 -6.02206  1.000 34.03146  ? 152 LEU A CB  1 
ATOM   893  C CG  . LEU A 1 153 ? -51.35434 -134.77314 -4.71122  1.000 40.75385  ? 152 LEU A CG  1 
ATOM   894  C CD1 . LEU A 1 153 ? -50.90557 -136.14842 -4.25733  1.000 43.32607  ? 152 LEU A CD1 1 
ATOM   895  C CD2 . LEU A 1 153 ? -50.15523 -133.84891 -4.87675  1.000 45.24147  ? 152 LEU A CD2 1 
ATOM   896  N N   . GLU A 1 154 ? -54.58172 -134.58012 -8.01243  1.000 31.23666  ? 153 GLU A N   1 
ATOM   897  C CA  . GLU A 1 154 ? -55.13678 -134.62043 -9.36202  1.000 34.11898  ? 153 GLU A CA  1 
ATOM   898  C C   . GLU A 1 154 ? -55.78820 -133.29044 -9.72045  1.000 37.24089  ? 153 GLU A C   1 
ATOM   899  O O   . GLU A 1 154 ? -55.64193 -132.80413 -10.84883 1.000 31.45836  ? 153 GLU A O   1 
ATOM   900  C CB  . GLU A 1 154 ? -56.13509 -135.77215 -9.49070  1.000 34.37955  ? 153 GLU A CB  1 
ATOM   901  C CG  . GLU A 1 154 ? -55.50339 -137.15546 -9.35870  1.000 36.42811  ? 153 GLU A CG  1 
ATOM   902  C CD  . GLU A 1 154 ? -54.80421 -137.60249 -10.63191 1.000 37.42617  ? 153 GLU A CD  1 
ATOM   903  O OE1 . GLU A 1 154 ? -55.35561 -137.36335 -11.72156 1.000 40.09287  ? 153 GLU A OE1 1 
ATOM   904  O OE2 . GLU A 1 154 ? -53.70739 -138.19084 -10.54213 1.000 37.85235  ? 153 GLU A OE2 1 
ATOM   905  N N   . ALA A 1 155 ? -56.48670 -132.67160 -8.75977  1.000 31.11825  ? 154 ALA A N   1 
ATOM   906  C CA  . ALA A 1 155 ? -57.12091 -131.38260 -9.01911  1.000 32.29735  ? 154 ALA A CA  1 
ATOM   907  C C   . ALA A 1 155 ? -56.08724 -130.30168 -9.31246  1.000 34.94016  ? 154 ALA A C   1 
ATOM   908  O O   . ALA A 1 155 ? -56.26032 -129.50628 -10.24645 1.000 33.69891  ? 154 ALA A O   1 
ATOM   909  C CB  . ALA A 1 155 ? -57.99876 -130.97972 -7.83542  1.000 34.51104  ? 154 ALA A CB  1 
ATOM   910  N N   . VAL A 1 156 ? -55.00648 -130.25845 -8.52871  1.000 30.16548  ? 155 VAL A N   1 
ATOM   911  C CA  . VAL A 1 156 ? -53.97998 -129.24209 -8.73458  1.000 30.82065  ? 155 VAL A CA  1 
ATOM   912  C C   . VAL A 1 156 ? -53.24482 -129.47809 -10.04965 1.000 35.28704  ? 155 VAL A C   1 
ATOM   913  O O   . VAL A 1 156 ? -52.90961 -128.52651 -10.76736 1.000 37.11263  ? 155 VAL A O   1 
ATOM   914  C CB  . VAL A 1 156 ? -53.01418 -129.20934 -7.53674  1.000 33.64723  ? 155 VAL A CB  1 
ATOM   915  C CG1 . VAL A 1 156 ? -51.87401 -128.23778 -7.79426  1.000 33.26761  ? 155 VAL A CG1 1 
ATOM   916  C CG2 . VAL A 1 156 ? -53.76641 -128.81985 -6.26452  1.000 36.59212  ? 155 VAL A CG2 1 
ATOM   917  N N   . ARG A 1 157 ? -52.97799 -130.74357 -10.38695 1.000 33.59752  ? 156 ARG A N   1 
ATOM   918  C CA  . ARG A 1 157 ? -52.40570 -131.04699 -11.69484 1.000 37.09714  ? 156 ARG A CA  1 
ATOM   919  C C   . ARG A 1 157 ? -53.29080 -130.51558 -12.81324 1.000 35.74299  ? 156 ARG A C   1 
ATOM   920  O O   . ARG A 1 157 ? -52.79251 -129.96601 -13.80227 1.000 35.62377  ? 156 ARG A O   1 
ATOM   921  C CB  . ARG A 1 157 ? -52.20268 -132.55353 -11.85386 1.000 36.59703  ? 156 ARG A CB  1 
ATOM   922  C CG  . ARG A 1 157 ? -51.00765 -133.12139 -11.11006 1.000 35.28521  ? 156 ARG A CG  1 
ATOM   923  C CD  . ARG A 1 157 ? -50.90081 -134.61520 -11.36620 1.000 37.55351  ? 156 ARG A CD  1 
ATOM   924  N NE  . ARG A 1 157 ? -50.72450 -134.91051 -12.78459 1.000 36.99614  ? 156 ARG A NE  1 
ATOM   925  C CZ  . ARG A 1 157 ? -50.84385 -136.11749 -13.32079 1.000 38.95258  ? 156 ARG A CZ  1 
ATOM   926  N NH1 . ARG A 1 157 ? -51.16480 -137.17212 -12.58807 1.000 33.49161  ? 156 ARG A NH1 1 
ATOM   927  N NH2 . ARG A 1 157 ? -50.63892 -136.27068 -14.62651 1.000 37.76064  ? 156 ARG A NH2 1 
ATOM   928  N N   . HIS A 1 158 ? -54.60929 -130.66705 -12.67028 1.000 34.77937  ? 157 HIS A N   1 
ATOM   929  C CA  . HIS A 1 158 ? -55.52853 -130.15109 -13.67857 1.000 35.88517  ? 157 HIS A CA  1 
ATOM   930  C C   . HIS A 1 158 ? -55.41119 -128.63730 -13.80734 1.000 37.36195  ? 157 HIS A C   1 
ATOM   931  O O   . HIS A 1 158 ? -55.38245 -128.10465 -14.92350 1.000 35.09225  ? 157 HIS A O   1 
ATOM   932  C CB  . HIS A 1 158 ? -56.96328 -130.55824 -13.33503 1.000 38.57550  ? 157 HIS A CB  1 
ATOM   933  C CG  . HIS A 1 158 ? -57.99924 -129.92349 -14.20921 1.000 43.19172  ? 157 HIS A CG  1 
ATOM   934  N ND1 . HIS A 1 158 ? -58.24890 -130.34576 -15.49814 1.000 41.13965  ? 157 HIS A ND1 1 
ATOM   935  C CD2 . HIS A 1 158 ? -58.85119 -128.89619 -13.97820 1.000 45.10422  ? 157 HIS A CD2 1 
ATOM   936  C CE1 . HIS A 1 158 ? -59.20985 -129.60569 -16.02267 1.000 43.71636  ? 157 HIS A CE1 1 
ATOM   937  N NE2 . HIS A 1 158 ? -59.59256 -128.71866 -15.12138 1.000 43.67123  ? 157 HIS A NE2 1 
ATOM   938  N N   . CYS A 1 159 ? -55.33757 -127.92816 -12.67571 1.000 34.61648  ? 158 CYS A N   1 
ATOM   939  C CA  . CYS A 1 159 ? -55.16356 -126.47757 -12.71327 1.000 32.68949  ? 158 CYS A CA  1 
ATOM   940  C C   . CYS A 1 159 ? -53.89371 -126.09795 -13.46101 1.000 35.82444  ? 158 CYS A C   1 
ATOM   941  O O   . CYS A 1 159 ? -53.91623 -125.24207 -14.35241 1.000 34.47760  ? 158 CYS A O   1 
ATOM   942  C CB  . CYS A 1 159 ? -55.12536 -125.90742 -11.29370 1.000 33.16745  ? 158 CYS A CB  1 
ATOM   943  S SG  . CYS A 1 159 ? -56.67806 -126.01987 -10.37932 1.000 35.45885  ? 158 CYS A SG  1 
ATOM   944  N N   . HIS A 1 160 ? -52.76820 -126.72109 -13.10056 1.000 32.74948  ? 159 HIS A N   1 
ATOM   945  C CA  . HIS A 1 160 ? -51.50496 -126.37478 -13.73926 1.000 37.69698  ? 159 HIS A CA  1 
ATOM   946  C C   . HIS A 1 160 ? -51.52770 -126.71615 -15.22505 1.000 34.64060  ? 159 HIS A C   1 
ATOM   947  O O   . HIS A 1 160 ? -50.99166 -125.96253 -16.04417 1.000 36.86869  ? 159 HIS A O   1 
ATOM   948  C CB  . HIS A 1 160 ? -50.34635 -127.07286 -13.02555 1.000 36.60671  ? 159 HIS A CB  1 
ATOM   949  C CG  . HIS A 1 160 ? -50.09562 -126.55753 -11.63994 1.000 39.34325  ? 159 HIS A CG  1 
ATOM   950  N ND1 . HIS A 1 160 ? -48.88727 -126.70939 -10.99567 1.000 43.38071  ? 159 HIS A ND1 1 
ATOM   951  C CD2 . HIS A 1 160 ? -50.89691 -125.88405 -10.77935 1.000 39.23619  ? 159 HIS A CD2 1 
ATOM   952  C CE1 . HIS A 1 160 ? -48.95567 -126.15694 -9.79696  1.000 41.85624  ? 159 HIS A CE1 1 
ATOM   953  N NE2 . HIS A 1 160 ? -50.16330 -125.64501 -9.64302  1.000 39.39835  ? 159 HIS A NE2 1 
ATOM   954  N N   . ASN A 1 161 ? -52.16981 -127.83033 -15.59543 1.000 35.18620  ? 160 ASN A N   1 
ATOM   955  C CA  . ASN A 1 161 ? -52.30217 -128.17477 -17.00984 1.000 41.12133  ? 160 ASN A CA  1 
ATOM   956  C C   . ASN A 1 161 ? -53.12844 -127.14518 -17.76732 1.000 41.17507  ? 160 ASN A C   1 
ATOM   957  O O   . ASN A 1 161 ? -52.94095 -126.96791 -18.97646 1.000 38.84976  ? 160 ASN A O   1 
ATOM   958  C CB  . ASN A 1 161 ? -52.93356 -129.55822 -17.16962 1.000 42.87993  ? 160 ASN A CB  1 
ATOM   959  C CG  . ASN A 1 161 ? -51.99217 -130.67609 -16.78885 1.000 48.03250  ? 160 ASN A CG  1 
ATOM   960  O OD1 . ASN A 1 161 ? -50.77210 -130.53816 -16.88713 1.000 54.63745  ? 160 ASN A OD1 1 
ATOM   961  N ND2 . ASN A 1 161 ? -52.55441 -131.79755 -16.35624 1.000 48.15194  ? 160 ASN A ND2 1 
ATOM   962  N N   . CYS A 1 162 ? -54.05205 -126.47170 -17.08669 1.000 37.69529  ? 161 CYS A N   1 
ATOM   963  C CA  . CYS A 1 162 ? -54.84852 -125.41908 -17.69763 1.000 38.33446  ? 161 CYS A CA  1 
ATOM   964  C C   . CYS A 1 162 ? -54.19962 -124.04625 -17.57100 1.000 37.47500  ? 161 CYS A C   1 
ATOM   965  O O   . CYS A 1 162 ? -54.81975 -123.04775 -17.94250 1.000 38.58977  ? 161 CYS A O   1 
ATOM   966  C CB  . CYS A 1 162 ? -56.24957 -125.39180 -17.07929 1.000 38.32904  ? 161 CYS A CB  1 
ATOM   967  S SG  . CYS A 1 162 ? -57.19905 -126.91101 -17.30725 1.000 43.16955  ? 161 CYS A SG  1 
ATOM   968  N N   . GLY A 1 163 ? -52.97549 -123.97349 -17.05273 1.000 36.70673  ? 162 GLY A N   1 
ATOM   969  C CA  . GLY A 1 163 ? -52.28686 -122.70333 -16.91770 1.000 35.35351  ? 162 GLY A CA  1 
ATOM   970  C C   . GLY A 1 163 ? -52.68290 -121.88154 -15.71305 1.000 39.58598  ? 162 GLY A C   1 
ATOM   971  O O   . GLY A 1 163 ? -52.48780 -120.66046 -15.71793 1.000 35.02952  ? 162 GLY A O   1 
ATOM   972  N N   . VAL A 1 164 ? -53.21866 -122.51239 -14.66966 1.000 35.21550  ? 163 VAL A N   1 
ATOM   973  C CA  . VAL A 1 164 ? -53.77443 -121.81309 -13.51754 1.000 34.41557  ? 163 VAL A CA  1 
ATOM   974  C C   . VAL A 1 164 ? -53.02740 -122.24406 -12.26283 1.000 36.90369  ? 163 VAL A C   1 
ATOM   975  O O   . VAL A 1 164 ? -52.83824 -123.44248 -12.02381 1.000 31.80243  ? 163 VAL A O   1 
ATOM   976  C CB  . VAL A 1 164 ? -55.28368 -122.08261 -13.37240 1.000 38.07428  ? 163 VAL A CB  1 
ATOM   977  C CG1 . VAL A 1 164 ? -55.80490 -121.50579 -12.06381 1.000 34.62329  ? 163 VAL A CG1 1 
ATOM   978  C CG2 . VAL A 1 164 ? -56.04051 -121.49959 -14.55960 1.000 35.97971  ? 163 VAL A CG2 1 
ATOM   979  N N   . LEU A 1 165 ? -52.61404 -121.26612 -11.46307 1.000 38.44669  ? 164 LEU A N   1 
ATOM   980  C CA  . LEU A 1 165 ? -52.00140 -121.49493 -10.16045 1.000 38.66259  ? 164 LEU A CA  1 
ATOM   981  C C   . LEU A 1 165 ? -52.97690 -121.02430 -9.08905  1.000 35.43739  ? 164 LEU A C   1 
ATOM   982  O O   . LEU A 1 165 ? -53.35116 -119.84759 -9.06542  1.000 36.74092  ? 164 LEU A O   1 
ATOM   983  C CB  . LEU A 1 165 ? -50.67236 -120.74903 -10.05060 1.000 39.36208  ? 164 LEU A CB  1 
ATOM   984  C CG  . LEU A 1 165 ? -49.81658 -121.00330 -8.80975  1.000 40.45543  ? 164 LEU A CG  1 
ATOM   985  C CD1 . LEU A 1 165 ? -49.23139 -122.40550 -8.84590  1.000 38.31095  ? 164 LEU A CD1 1 
ATOM   986  C CD2 . LEU A 1 165 ? -48.71484 -119.95740 -8.72320  1.000 38.64554  ? 164 LEU A CD2 1 
ATOM   987  N N   . HIS A 1 166 ? -53.38467 -121.93820 -8.20492  1.000 36.55328  ? 165 HIS A N   1 
ATOM   988  C CA  . HIS A 1 166 ? -54.43568 -121.61897 -7.23910  1.000 33.84279  ? 165 HIS A CA  1 
ATOM   989  C C   . HIS A 1 166 ? -53.93939 -120.65776 -6.16186  1.000 35.77087  ? 165 HIS A C   1 
ATOM   990  O O   . HIS A 1 166 ? -54.63337 -119.69595 -5.80796  1.000 36.83555  ? 165 HIS A O   1 
ATOM   991  C CB  . HIS A 1 166 ? -54.97215 -122.90446 -6.60686  1.000 36.05385  ? 165 HIS A CB  1 
ATOM   992  C CG  . HIS A 1 166 ? -56.15778 -122.69049 -5.71864  1.000 36.03072  ? 165 HIS A CG  1 
ATOM   993  N ND1 . HIS A 1 166 ? -56.04347 -122.25296 -4.41658  1.000 33.60785  ? 165 HIS A ND1 1 
ATOM   994  C CD2 . HIS A 1 166 ? -57.48297 -122.85100 -5.94631  1.000 37.57560  ? 165 HIS A CD2 1 
ATOM   995  C CE1 . HIS A 1 166 ? -57.24647 -122.15906 -3.87825  1.000 35.54616  ? 165 HIS A CE1 1 
ATOM   996  N NE2 . HIS A 1 166 ? -58.13807 -122.51295 -4.78617  1.000 36.20872  ? 165 HIS A NE2 1 
ATOM   997  N N   . ARG A 1 167 ? -52.76032 -120.92880 -5.60008  1.000 33.68243  ? 166 ARG A N   1 
ATOM   998  C CA  . ARG A 1 167 ? -52.06637 -120.09901 -4.61272  1.000 36.45408  ? 166 ARG A CA  1 
ATOM   999  C C   . ARG A 1 167 ? -52.76063 -120.01366 -3.25628  1.000 39.32656  ? 166 ARG A C   1 
ATOM   1000 O O   . ARG A 1 167 ? -52.32982 -119.22200 -2.40531  1.000 40.25912  ? 166 ARG A O   1 
ATOM   1001 C CB  . ARG A 1 167 ? -51.82599 -118.67463 -5.12754  1.000 35.29280  ? 166 ARG A CB  1 
ATOM   1002 C CG  . ARG A 1 167 ? -50.94969 -118.61790 -6.36214  1.000 37.51697  ? 166 ARG A CG  1 
ATOM   1003 C CD  . ARG A 1 167 ? -50.27997 -117.26433 -6.52344  1.000 41.88237  ? 166 ARG A CD  1 
ATOM   1004 N NE  . ARG A 1 167 ? -51.24058 -116.19274 -6.75418  1.000 40.84936  ? 166 ARG A NE  1 
ATOM   1005 C CZ  . ARG A 1 167 ? -50.90510 -114.93914 -7.02629  1.000 45.51394  ? 166 ARG A CZ  1 
ATOM   1006 N NH1 . ARG A 1 167 ? -49.63797 -114.56523 -7.10590  1.000 46.25706  ? 166 ARG A NH1 1 
ATOM   1007 N NH2 . ARG A 1 167 ? -51.86411 -114.03941 -7.22793  1.000 41.58436  ? 166 ARG A NH2 1 
ATOM   1008 N N   . ASP A 1 168 ? -53.80744 -120.79372 -3.00967  1.000 33.68438  ? 167 ASP A N   1 
ATOM   1009 C CA  . ASP A 1 168 ? -54.42668 -120.80087 -1.68634  1.000 34.27954  ? 167 ASP A CA  1 
ATOM   1010 C C   . ASP A 1 168 ? -54.94914 -122.19975 -1.36417  1.000 31.72510  ? 167 ASP A C   1 
ATOM   1011 O O   . ASP A 1 168 ? -56.07197 -122.37650 -0.88990  1.000 34.41913  ? 167 ASP A O   1 
ATOM   1012 C CB  . ASP A 1 168 ? -55.53440 -119.75066 -1.59186  1.000 35.85625  ? 167 ASP A CB  1 
ATOM   1013 C CG  . ASP A 1 168 ? -55.87927 -119.38544 -0.14985  1.000 42.39089  ? 167 ASP A CG  1 
ATOM   1014 O OD1 . ASP A 1 168 ? -55.11439 -119.75684 0.76932   1.000 38.67861  ? 167 ASP A OD1 1 
ATOM   1015 O OD2 . ASP A 1 168 ? -56.92065 -118.72726 0.06432   1.000 44.61444  ? 167 ASP A OD2 1 
ATOM   1016 N N   . ILE A 1 169 ? -54.12730 -123.21715 -1.61694  1.000 31.82815  ? 168 ILE A N   1 
ATOM   1017 C CA  . ILE A 1 169 ? -54.49498 -124.58518 -1.26772  1.000 30.31796  ? 168 ILE A CA  1 
ATOM   1018 C C   . ILE A 1 169 ? -54.52510 -124.71001 0.25153   1.000 33.51964  ? 168 ILE A C   1 
ATOM   1019 O O   . ILE A 1 169 ? -53.51797 -124.46815 0.92608   1.000 32.75970  ? 168 ILE A O   1 
ATOM   1020 C CB  . ILE A 1 169 ? -53.51881 -125.59366 -1.88881  1.000 32.24189  ? 168 ILE A CB  1 
ATOM   1021 C CG1 . ILE A 1 169 ? -53.48356 -125.45479 -3.41741  1.000 32.33653  ? 168 ILE A CG1 1 
ATOM   1022 C CG2 . ILE A 1 169 ? -53.90160 -127.01785 -1.50282  1.000 30.37229  ? 168 ILE A CG2 1 
ATOM   1023 C CD1 . ILE A 1 169 ? -52.33716 -126.22133 -4.07024  1.000 29.03770  ? 168 ILE A CD1 1 
ATOM   1024 N N   . LYS A 1 170 ? -55.68664 -125.06975 0.79529   1.000 32.60008  ? 169 LYS A N   1 
ATOM   1025 C CA  . LYS A 1 170 ? -55.84191 -125.30812 2.22718   1.000 33.33413  ? 169 LYS A CA  1 
ATOM   1026 C C   . LYS A 1 170 ? -57.15235 -126.05164 2.44632   1.000 33.56256  ? 169 LYS A C   1 
ATOM   1027 O O   . LYS A 1 170 ? -57.98766 -126.14598 1.54276   1.000 33.06304  ? 169 LYS A O   1 
ATOM   1028 C CB  . LYS A 1 170 ? -55.80383 -124.00145 3.02972   1.000 33.20168  ? 169 LYS A CB  1 
ATOM   1029 C CG  . LYS A 1 170 ? -56.85458 -122.97249 2.64100   1.000 35.45627  ? 169 LYS A CG  1 
ATOM   1030 C CD  . LYS A 1 170 ? -56.77540 -121.75812 3.56061   1.000 36.91495  ? 169 LYS A CD  1 
ATOM   1031 C CE  . LYS A 1 170 ? -57.79124 -120.69364 3.17431   1.000 39.91911  ? 169 LYS A CE  1 
ATOM   1032 N NZ  . LYS A 1 170 ? -57.73577 -119.52017 4.09863   1.000 40.33887  ? 169 LYS A NZ  1 
ATOM   1033 N N   . ASP A 1 171 ? -57.32920 -126.58157 3.66589   1.000 31.77377  ? 170 ASP A N   1 
ATOM   1034 C CA  . ASP A 1 171 ? -58.52100 -127.38369 3.93001   1.000 32.63455  ? 170 ASP A CA  1 
ATOM   1035 C C   . ASP A 1 171 ? -59.79157 -126.55093 3.81944   1.000 32.56133  ? 170 ASP A C   1 
ATOM   1036 O O   . ASP A 1 171 ? -60.83735 -127.07191 3.41429   1.000 32.48985  ? 170 ASP A O   1 
ATOM   1037 C CB  . ASP A 1 171 ? -58.42976 -128.07985 5.29820   1.000 31.69590  ? 170 ASP A CB  1 
ATOM   1038 C CG  . ASP A 1 171 ? -58.16002 -127.12174 6.46111   1.000 35.36565  ? 170 ASP A CG  1 
ATOM   1039 O OD1 . ASP A 1 171 ? -58.14005 -125.88957 6.27301   1.000 31.35581  ? 170 ASP A OD1 1 
ATOM   1040 O OD2 . ASP A 1 171 ? -57.95788 -127.62664 7.58613   1.000 36.35084  ? 170 ASP A OD2 1 
ATOM   1041 N N   . GLU A 1 172 ? -59.71163 -125.25305 4.13112   1.000 31.12940  ? 171 GLU A N   1 
ATOM   1042 C CA  . GLU A 1 172 ? -60.87500 -124.38037 4.00096   1.000 37.02303  ? 171 GLU A CA  1 
ATOM   1043 C C   . GLU A 1 172 ? -61.34164 -124.26126 2.55644   1.000 34.64801  ? 171 GLU A C   1 
ATOM   1044 O O   . GLU A 1 172 ? -62.51737 -123.97159 2.30860   1.000 35.21069  ? 171 GLU A O   1 
ATOM   1045 C CB  . GLU A 1 172 ? -60.56057 -122.98792 4.54111   1.000 34.42076  ? 171 GLU A CB  1 
ATOM   1046 C CG  . GLU A 1 172 ? -60.04130 -122.94715 5.96599   1.000 38.09312  ? 171 GLU A CG  1 
ATOM   1047 C CD  . GLU A 1 172 ? -59.83791 -121.52528 6.43583   1.000 39.22973  ? 171 GLU A CD  1 
ATOM   1048 O OE1 . GLU A 1 172 ? -60.83749 -120.78466 6.52280   1.000 43.76957  ? 171 GLU A OE1 1 
ATOM   1049 O OE2 . GLU A 1 172 ? -58.67842 -121.13750 6.67855   1.000 42.35948  ? 171 GLU A OE2 1 
ATOM   1050 N N   . ASN A 1 173 ? -60.44261 -124.45417 1.59186   1.000 34.54922  ? 172 ASN A N   1 
ATOM   1051 C CA  . ASN A 1 173 ? -60.78214 -124.30307 0.18142   1.000 35.39187  ? 172 ASN A CA  1 
ATOM   1052 C C   . ASN A 1 173 ? -60.96767 -125.64267 -0.51757  1.000 34.07374  ? 172 ASN A C   1 
ATOM   1053 O O   . ASN A 1 173 ? -60.72721 -125.75665 -1.72455  1.000 36.38365  ? 172 ASN A O   1 
ATOM   1054 C CB  . ASN A 1 173 ? -59.72744 -123.45590 -0.52722  1.000 32.37561  ? 172 ASN A CB  1 
ATOM   1055 C CG  . ASN A 1 173 ? -59.78640 -122.00224 -0.10362  1.000 35.96056  ? 172 ASN A CG  1 
ATOM   1056 O OD1 . ASN A 1 173 ? -60.83433 -121.52406 0.32629   1.000 37.23918  ? 172 ASN A OD1 1 
ATOM   1057 N ND2 . ASN A 1 173 ? -58.66835 -121.29365 -0.21856  1.000 33.67048  ? 172 ASN A ND2 1 
ATOM   1058 N N   . ILE A 1 174 ? -61.41826 -126.65528 0.21799   1.000 35.01128  ? 173 ILE A N   1 
ATOM   1059 C CA  . ILE A 1 174 ? -61.67346 -127.98250 -0.32554  1.000 35.09579  ? 173 ILE A CA  1 
ATOM   1060 C C   . ILE A 1 174 ? -63.04132 -128.43721 0.16098   1.000 37.55566  ? 173 ILE A C   1 
ATOM   1061 O O   . ILE A 1 174 ? -63.27722 -128.51798 1.37420   1.000 34.18810  ? 173 ILE A O   1 
ATOM   1062 C CB  . ILE A 1 174 ? -60.58671 -128.98902 0.08558   1.000 33.80005  ? 173 ILE A CB  1 
ATOM   1063 C CG1 . ILE A 1 174 ? -59.25537 -128.62192 -0.57715  1.000 35.30226  ? 173 ILE A CG1 1 
ATOM   1064 C CG2 . ILE A 1 174 ? -61.01046 -130.40705 -0.27624  1.000 35.40082  ? 173 ILE A CG2 1 
ATOM   1065 C CD1 . ILE A 1 174 ? -58.05982 -129.35559 -0.00676  1.000 32.96195  ? 173 ILE A CD1 1 
ATOM   1066 N N   . LEU A 1 175 ? -63.93955 -128.72478 -0.77822  1.000 34.66238  ? 174 LEU A N   1 
ATOM   1067 C CA  . LEU A 1 175 ? -65.25785 -129.25497 -0.46554  1.000 38.61958  ? 174 LEU A CA  1 
ATOM   1068 C C   . LEU A 1 175 ? -65.27034 -130.76314 -0.66055  1.000 38.30548  ? 174 LEU A C   1 
ATOM   1069 O O   . LEU A 1 175 ? -64.67893 -131.28197 -1.61086  1.000 40.13886  ? 174 LEU A O   1 
ATOM   1070 C CB  . LEU A 1 175 ? -66.33550 -128.61484 -1.33997  1.000 38.90957  ? 174 LEU A CB  1 
ATOM   1071 C CG  . LEU A 1 175 ? -66.74098 -127.18282 -1.00704  1.000 40.16990  ? 174 LEU A CG  1 
ATOM   1072 C CD1 . LEU A 1 175 ? -67.93864 -126.77692 -1.84757  1.000 41.65551  ? 174 LEU A CD1 1 
ATOM   1073 C CD2 . LEU A 1 175 ? -67.05100 -127.04996 0.48005   1.000 42.05054  ? 174 LEU A CD2 1 
ATOM   1074 N N   . ILE A 1 176 ? -65.95321 -131.46073 0.24075   1.000 36.67180  ? 175 ILE A N   1 
ATOM   1075 C CA  . ILE A 1 176 ? -66.10058 -132.90993 0.18216   1.000 37.99245  ? 175 ILE A CA  1 
ATOM   1076 C C   . ILE A 1 176 ? -67.53482 -133.22211 -0.21883  1.000 44.89942  ? 175 ILE A C   1 
ATOM   1077 O O   . ILE A 1 176 ? -68.47685 -132.86482 0.49907   1.000 45.92689  ? 175 ILE A O   1 
ATOM   1078 C CB  . ILE A 1 176 ? -65.76368 -133.57003 1.52662   1.000 40.34176  ? 175 ILE A CB  1 
ATOM   1079 C CG1 . ILE A 1 176 ? -64.36276 -133.17467 1.99422   1.000 37.72430  ? 175 ILE A CG1 1 
ATOM   1080 C CG2 . ILE A 1 176 ? -65.90364 -135.08328 1.42753   1.000 37.59231  ? 175 ILE A CG2 1 
ATOM   1081 C CD1 . ILE A 1 176 ? -64.13673 -133.44128 3.47665   1.000 38.15673  ? 175 ILE A CD1 1 
ATOM   1082 N N   . ASP A 1 177 ? -67.70443 -133.88477 -1.35977  1.000 40.80055  ? 176 ASP A N   1 
ATOM   1083 C CA  . ASP A 1 177 ? -69.00118 -134.45057 -1.72720  1.000 44.20085  ? 176 ASP A CA  1 
ATOM   1084 C C   . ASP A 1 177 ? -69.17894 -135.71969 -0.90432  1.000 47.61929  ? 176 ASP A C   1 
ATOM   1085 O O   . ASP A 1 177 ? -68.60187 -136.76434 -1.21658  1.000 50.10813  ? 176 ASP A O   1 
ATOM   1086 C CB  . ASP A 1 177 ? -69.07267 -134.72556 -3.22644  1.000 45.82739  ? 176 ASP A CB  1 
ATOM   1087 C CG  . ASP A 1 177 ? -70.46025 -135.17089 -3.68267  1.000 47.46332  ? 176 ASP A CG  1 
ATOM   1088 O OD1 . ASP A 1 177 ? -71.13343 -135.92434 -2.94791  1.000 49.80777  ? 176 ASP A OD1 1 
ATOM   1089 O OD2 . ASP A 1 177 ? -70.87756 -134.76895 -4.78779  1.000 51.78819  ? 176 ASP A OD2 1 
ATOM   1090 N N   . LEU A 1 178 ? -69.99089 -135.62909 0.15253   1.000 46.11617  ? 177 LEU A N   1 
ATOM   1091 C CA  . LEU A 1 178 ? -70.09064 -136.70522 1.13234   1.000 48.58165  ? 177 LEU A CA  1 
ATOM   1092 C C   . LEU A 1 178 ? -70.72377 -137.97239 0.56939   1.000 51.74876  ? 177 LEU A C   1 
ATOM   1093 O O   . LEU A 1 178 ? -70.47443 -139.05825 1.10296   1.000 54.76516  ? 177 LEU A O   1 
ATOM   1094 C CB  . LEU A 1 178 ? -70.88203 -136.22488 2.34996   1.000 50.00487  ? 177 LEU A CB  1 
ATOM   1095 C CG  . LEU A 1 178 ? -70.24613 -135.08430 3.15119   1.000 53.32958  ? 177 LEU A CG  1 
ATOM   1096 C CD1 . LEU A 1 178 ? -71.19958 -134.57596 4.22342   1.000 46.96430  ? 177 LEU A CD1 1 
ATOM   1097 C CD2 . LEU A 1 178 ? -68.93050 -135.53740 3.77692   1.000 45.18904  ? 177 LEU A CD2 1 
ATOM   1098 N N   . ASN A 1 179 ? -71.53510 -137.86736 -0.48266  1.000 50.61165  ? 178 ASN A N   1 
ATOM   1099 C CA  . ASN A 1 179 ? -72.16072 -139.05113 -1.06211  1.000 53.08936  ? 178 ASN A CA  1 
ATOM   1100 C C   . ASN A 1 179 ? -71.28844 -139.71303 -2.12205  1.000 53.45296  ? 178 ASN A C   1 
ATOM   1101 O O   . ASN A 1 179 ? -71.21880 -140.94546 -2.18148  1.000 52.27055  ? 178 ASN A O   1 
ATOM   1102 C CB  . ASN A 1 179 ? -73.52365 -138.69674 -1.66459  1.000 56.38829  ? 178 ASN A CB  1 
ATOM   1103 C CG  . ASN A 1 179 ? -74.61319 -138.57658 -0.61512  1.000 60.62108  ? 178 ASN A CG  1 
ATOM   1104 O OD1 . ASN A 1 179 ? -74.40883 -138.91052 0.55236   1.000 61.53764  ? 178 ASN A OD1 1 
ATOM   1105 N ND2 . ASN A 1 179 ? -75.78398 -138.10924 -1.03088  1.000 65.95432  ? 178 ASN A ND2 1 
ATOM   1106 N N   . ARG A 1 180 ? -70.62291 -138.92486 -2.96423  1.000 46.46227  ? 179 ARG A N   1 
ATOM   1107 C CA  . ARG A 1 180 ? -69.76194 -139.47945 -3.99906  1.000 49.06778  ? 179 ARG A CA  1 
ATOM   1108 C C   . ARG A 1 180 ? -68.32103 -139.66781 -3.54115  1.000 49.59238  ? 179 ARG A C   1 
ATOM   1109 O O   . ARG A 1 180 ? -67.56014 -140.36786 -4.21841  1.000 46.81176  ? 179 ARG A O   1 
ATOM   1110 C CB  . ARG A 1 180 ? -69.79385 -138.58785 -5.24741  1.000 48.24875  ? 179 ARG A CB  1 
ATOM   1111 C CG  . ARG A 1 180 ? -71.18379 -138.43054 -5.85751  1.000 49.15883  ? 179 ARG A CG  1 
ATOM   1112 C CD  . ARG A 1 180 ? -71.17482 -137.49180 -7.05527  1.000 49.33015  ? 179 ARG A CD  1 
ATOM   1113 N NE  . ARG A 1 180 ? -70.40901 -138.02904 -8.17351  1.000 60.32220  ? 179 ARG A NE  1 
ATOM   1114 N N   . GLY A 1 181 ? -67.93048 -139.07780 -2.41378  1.000 45.78503  ? 180 GLY A N   1 
ATOM   1115 C CA  . GLY A 1 181 ? -66.55468 -139.18206 -1.96462  1.000 46.27743  ? 180 GLY A CA  1 
ATOM   1116 C C   . GLY A 1 181 ? -65.56378 -138.42872 -2.82457  1.000 47.82702  ? 180 GLY A C   1 
ATOM   1117 O O   . GLY A 1 181 ? -64.38874 -138.80374 -2.87872  1.000 44.60820  ? 180 GLY A O   1 
ATOM   1118 N N   . GLU A 1 182 ? -66.00699 -137.37246 -3.49943  1.000 43.17273  ? 181 GLU A N   1 
ATOM   1119 C CA  . GLU A 1 182 ? -65.16156 -136.57559 -4.37492  1.000 47.11400  ? 181 GLU A CA  1 
ATOM   1120 C C   . GLU A 1 182 ? -64.85548 -135.23247 -3.72796  1.000 41.46348  ? 181 GLU A C   1 
ATOM   1121 O O   . GLU A 1 182 ? -65.72788 -134.61768 -3.10592  1.000 41.16531  ? 181 GLU A O   1 
ATOM   1122 C CB  . GLU A 1 182 ? -65.83262 -136.35137 -5.73341  1.000 40.82951  ? 181 GLU A CB  1 
ATOM   1123 C CG  . GLU A 1 182 ? -66.17103 -137.63175 -6.47188  1.000 48.54066  ? 181 GLU A CG  1 
ATOM   1124 C CD  . GLU A 1 182 ? -67.03440 -137.39190 -7.69743  1.000 52.01300  ? 181 GLU A CD  1 
ATOM   1125 O OE1 . GLU A 1 182 ? -67.39006 -136.22535 -7.96395  1.000 54.26680  ? 181 GLU A OE1 1 
ATOM   1126 O OE2 . GLU A 1 182 ? -67.35877 -138.37504 -8.39193  1.000 59.92260  ? 181 GLU A OE2 1 
ATOM   1127 N N   . LEU A 1 183 ? -63.61620 -134.78029 -3.88890  1.000 38.73196  ? 182 LEU A N   1 
ATOM   1128 C CA  . LEU A 1 183 ? -63.17012 -133.49505 -3.37638  1.000 36.58296  ? 182 LEU A CA  1 
ATOM   1129 C C   . LEU A 1 183 ? -63.14355 -132.46262 -4.49460  1.000 41.13602  ? 182 LEU A C   1 
ATOM   1130 O O   . LEU A 1 183 ? -62.84870 -132.78050 -5.65016  1.000 39.38882  ? 182 LEU A O   1 
ATOM   1131 C CB  . LEU A 1 183 ? -61.78272 -133.61026 -2.74031  1.000 31.58070  ? 182 LEU A CB  1 
ATOM   1132 C CG  . LEU A 1 183 ? -61.74543 -133.92397 -1.24018  1.000 40.28533  ? 182 LEU A CG  1 
ATOM   1133 C CD1 . LEU A 1 183 ? -62.50400 -135.20299 -0.91853  1.000 41.60809  ? 182 LEU A CD1 1 
ATOM   1134 C CD2 . LEU A 1 183 ? -60.30502 -134.01187 -0.75032  1.000 39.50391  ? 182 LEU A CD2 1 
ATOM   1135 N N   . LYS A 1 184 ? -63.45533 -131.21723 -4.13780  1.000 38.84200  ? 183 LYS A N   1 
ATOM   1136 C CA  . LYS A 1 184 ? -63.48111 -130.11234 -5.08808  1.000 39.88649  ? 183 LYS A CA  1 
ATOM   1137 C C   . LYS A 1 184 ? -62.68789 -128.93830 -4.53662  1.000 36.59036  ? 183 LYS A C   1 
ATOM   1138 O O   . LYS A 1 184 ? -62.93786 -128.48364 -3.41596  1.000 34.81502  ? 183 LYS A O   1 
ATOM   1139 C CB  . LYS A 1 184 ? -64.91522 -129.66653 -5.39909  1.000 42.85124  ? 183 LYS A CB  1 
ATOM   1140 C CG  . LYS A 1 184 ? -65.71926 -130.65739 -6.21843  1.000 50.07489  ? 183 LYS A CG  1 
ATOM   1141 C CD  . LYS A 1 184 ? -66.64824 -129.93534 -7.18093  1.000 54.92377  ? 183 LYS A CD  1 
ATOM   1142 C CE  . LYS A 1 184 ? -67.62084 -130.89751 -7.83696  1.000 63.12771  ? 183 LYS A CE  1 
ATOM   1143 N NZ  . LYS A 1 184 ? -66.92791 -132.03324 -8.50354  1.000 63.02481  ? 183 LYS A NZ  1 
ATOM   1144 N N   . LEU A 1 185 ? -61.74090 -128.44938 -5.32976  1.000 36.23917  ? 184 LEU A N   1 
ATOM   1145 C CA  . LEU A 1 185 ? -60.99190 -127.24849 -4.98962  1.000 35.57763  ? 184 LEU A CA  1 
ATOM   1146 C C   . LEU A 1 185 ? -61.83538 -126.02060 -5.31655  1.000 39.00693  ? 184 LEU A C   1 
ATOM   1147 O O   . LEU A 1 185 ? -62.43517 -125.94368 -6.39385  1.000 37.42545  ? 184 LEU A O   1 
ATOM   1148 C CB  . LEU A 1 185 ? -59.67487 -127.22719 -5.76527  1.000 34.35097  ? 184 LEU A CB  1 
ATOM   1149 C CG  . LEU A 1 185 ? -58.62079 -126.17178 -5.45075  1.000 38.24560  ? 184 LEU A CG  1 
ATOM   1150 C CD1 . LEU A 1 185 ? -58.11844 -126.32124 -4.02120  1.000 37.72659  ? 184 LEU A CD1 1 
ATOM   1151 C CD2 . LEU A 1 185 ? -57.47173 -126.30730 -6.44821  1.000 41.31540  ? 184 LEU A CD2 1 
ATOM   1152 N N   . ILE A 1 186 ? -61.89947 -125.06626 -4.38414  1.000 33.32682  ? 185 ILE A N   1 
ATOM   1153 C CA  . ILE A 1 186 ? -62.75045 -123.89205 -4.53450  1.000 37.56283  ? 185 ILE A CA  1 
ATOM   1154 C C   . ILE A 1 186 ? -61.93984 -122.63160 -4.25531  1.000 36.72775  ? 185 ILE A C   1 
ATOM   1155 O O   . ILE A 1 186 ? -60.77945 -122.68237 -3.84761  1.000 36.49293  ? 185 ILE A O   1 
ATOM   1156 C CB  . ILE A 1 186 ? -63.99182 -123.93581 -3.61520  1.000 38.42261  ? 185 ILE A CB  1 
ATOM   1157 C CG1 . ILE A 1 186 ? -63.56985 -123.91355 -2.14199  1.000 35.72560  ? 185 ILE A CG1 1 
ATOM   1158 C CG2 . ILE A 1 186 ? -64.85061 -125.15921 -3.91917  1.000 38.18945  ? 185 ILE A CG2 1 
ATOM   1159 C CD1 . ILE A 1 186 ? -64.73091 -123.72070 -1.17848  1.000 37.66903  ? 185 ILE A CD1 1 
ATOM   1160 N N   . ASP A 1 187 ? -62.59032 -121.48803 -4.48061  1.000 34.65416  ? 186 ASP A N   1 
ATOM   1161 C CA  . ASP A 1 187 ? -62.04704 -120.15876 -4.22033  1.000 34.46598  ? 186 ASP A CA  1 
ATOM   1162 C C   . ASP A 1 187 ? -60.73106 -119.91227 -4.94730  1.000 41.41988  ? 186 ASP A C   1 
ATOM   1163 O O   . ASP A 1 187 ? -59.65031 -120.02740 -4.35748  1.000 36.90700  ? 186 ASP A O   1 
ATOM   1164 C CB  . ASP A 1 187 ? -61.86541 -119.92446 -2.71831  1.000 41.32597  ? 186 ASP A CB  1 
ATOM   1165 C CG  . ASP A 1 187 ? -61.66189 -118.45736 -2.38597  1.000 46.27762  ? 186 ASP A CG  1 
ATOM   1166 O OD1 . ASP A 1 187 ? -61.73129 -117.62696 -3.31780  1.000 45.44908  ? 186 ASP A OD1 1 
ATOM   1167 O OD2 . ASP A 1 187 ? -61.42716 -118.12988 -1.20393  1.000 51.47310  ? 186 ASP A OD2 1 
ATOM   1168 N N   . PHE A 1 188 ? -60.82158 -119.54864 -6.22579  1.000 33.44507  ? 187 PHE A N   1 
ATOM   1169 C CA  . PHE A 1 188 ? -59.67234 -119.14665 -7.02138  1.000 39.15997  ? 187 PHE A CA  1 
ATOM   1170 C C   . PHE A 1 188 ? -59.40961 -117.64605 -6.94469  1.000 40.03839  ? 187 PHE A C   1 
ATOM   1171 O O   . PHE A 1 188 ? -58.71189 -117.10111 -7.80890  1.000 39.07746  ? 187 PHE A O   1 
ATOM   1172 C CB  . PHE A 1 188 ? -59.86806 -119.58178 -8.47851  1.000 35.74965  ? 187 PHE A CB  1 
ATOM   1173 C CG  . PHE A 1 188 ? -59.70629 -121.06094 -8.69271  1.000 36.54002  ? 187 PHE A CG  1 
ATOM   1174 C CD1 . PHE A 1 188 ? -60.69859 -121.94671 -8.30456  1.000 36.49025  ? 187 PHE A CD1 1 
ATOM   1175 C CD2 . PHE A 1 188 ? -58.55775 -121.56534 -9.27860  1.000 36.06746  ? 187 PHE A CD2 1 
ATOM   1176 C CE1 . PHE A 1 188 ? -60.54602 -123.30813 -8.49150  1.000 37.64295  ? 187 PHE A CE1 1 
ATOM   1177 C CE2 . PHE A 1 188 ? -58.40041 -122.92540 -9.47141  1.000 35.34637  ? 187 PHE A CE2 1 
ATOM   1178 C CZ  . PHE A 1 188 ? -59.39556 -123.79776 -9.07840  1.000 38.34894  ? 187 PHE A CZ  1 
ATOM   1179 N N   . GLY A 1 189 ? -59.94504 -116.97192 -5.92536  1.000 38.47758  ? 188 GLY A N   1 
ATOM   1180 C CA  . GLY A 1 189 ? -59.82999 -115.52769 -5.80539  1.000 42.99153  ? 188 GLY A CA  1 
ATOM   1181 C C   . GLY A 1 189 ? -58.43981 -115.01892 -5.48117  1.000 43.00243  ? 188 GLY A C   1 
ATOM   1182 O O   . GLY A 1 189 ? -58.21854 -113.80524 -5.54302  1.000 44.96411  ? 188 GLY A O   1 
ATOM   1183 N N   . SER A 1 190 ? -57.50768 -115.90274 -5.13188  1.000 39.83098  ? 189 SER A N   1 
ATOM   1184 C CA  . SER A 1 190 ? -56.12536 -115.52047 -4.87030  1.000 41.04679  ? 189 SER A CA  1 
ATOM   1185 C C   . SER A 1 190 ? -55.16856 -116.06845 -5.92047  1.000 40.46335  ? 189 SER A C   1 
ATOM   1186 O O   . SER A 1 190 ? -53.95143 -115.91377 -5.78185  1.000 41.88259  ? 189 SER A O   1 
ATOM   1187 C CB  . SER A 1 190 ? -55.69371 -115.99479 -3.47894  1.000 46.20510  ? 189 SER A CB  1 
ATOM   1188 O OG  . SER A 1 190 ? -56.54000 -115.48040 -2.46349  1.000 51.81477  ? 189 SER A OG  1 
ATOM   1189 N N   . GLY A 1 191 ? -55.68778 -116.70447 -6.96583  1.000 36.78849  ? 190 GLY A N   1 
ATOM   1190 C CA  . GLY A 1 191 ? -54.85389 -117.38166 -7.92977  1.000 40.07912  ? 190 GLY A CA  1 
ATOM   1191 C C   . GLY A 1 191 ? -54.23125 -116.44787 -8.94820  1.000 42.82103  ? 190 GLY A C   1 
ATOM   1192 O O   . GLY A 1 191 ? -54.38298 -115.22692 -8.91069  1.000 43.32411  ? 190 GLY A O   1 
ATOM   1193 N N   . ALA A 1 192 ? -53.51189 -117.05708 -9.88643  1.000 39.91015  ? 191 ALA A N   1 
ATOM   1194 C CA  . ALA A 1 192 ? -52.85711 -116.32231 -10.95910 1.000 41.02910  ? 191 ALA A CA  1 
ATOM   1195 C C   . ALA A 1 192 ? -52.61442 -117.27727 -12.11564 1.000 41.93980  ? 191 ALA A C   1 
ATOM   1196 O O   . ALA A 1 192 ? -52.70832 -118.49930 -11.97028 1.000 39.89359  ? 191 ALA A O   1 
ATOM   1197 C CB  . ALA A 1 192 ? -51.54152 -115.69110 -10.49000 1.000 37.49863  ? 191 ALA A CB  1 
ATOM   1198 N N   . LEU A 1 193 ? -52.31193 -116.70098 -13.27608 1.000 41.95646  ? 192 LEU A N   1 
ATOM   1199 C CA  . LEU A 1 193 ? -51.84211 -117.50904 -14.38940 1.000 39.49951  ? 192 LEU A CA  1 
ATOM   1200 C C   . LEU A 1 193 ? -50.52843 -118.17713 -14.00704 1.000 39.86515  ? 192 LEU A C   1 
ATOM   1201 O O   . LEU A 1 193 ? -49.68052 -117.57903 -13.33986 1.000 40.61073  ? 192 LEU A O   1 
ATOM   1202 C CB  . LEU A 1 193 ? -51.66322 -116.64503 -15.63999 1.000 44.05399  ? 192 LEU A CB  1 
ATOM   1203 C CG  . LEU A 1 193 ? -52.91895 -115.92430 -16.14677 1.000 46.48085  ? 192 LEU A CG  1 
ATOM   1204 C CD1 . LEU A 1 193 ? -52.59000 -115.01728 -17.32804 1.000 49.80879  ? 192 LEU A CD1 1 
ATOM   1205 C CD2 . LEU A 1 193 ? -54.00265 -116.92336 -16.52818 1.000 43.79443  ? 192 LEU A CD2 1 
ATOM   1206 N N   . LEU A 1 194 ? -50.37217 -119.43529 -14.40360 1.000 40.39781  ? 193 LEU A N   1 
ATOM   1207 C CA  . LEU A 1 194 ? -49.14010 -120.15035 -14.10324 1.000 40.28201  ? 193 LEU A CA  1 
ATOM   1208 C C   . LEU A 1 194 ? -48.01439 -119.63455 -14.99141 1.000 42.26706  ? 193 LEU A C   1 
ATOM   1209 O O   . LEU A 1 194 ? -48.18062 -119.50076 -16.20664 1.000 43.42098  ? 193 LEU A O   1 
ATOM   1210 C CB  . LEU A 1 194 ? -49.33223 -121.65284 -14.30307 1.000 43.81390  ? 193 LEU A CB  1 
ATOM   1211 C CG  . LEU A 1 194 ? -48.12196 -122.54523 -14.01339 1.000 45.98934  ? 193 LEU A CG  1 
ATOM   1212 C CD1 . LEU A 1 194 ? -47.67625 -122.40571 -12.56222 1.000 40.52198  ? 193 LEU A CD1 1 
ATOM   1213 C CD2 . LEU A 1 194 ? -48.43793 -123.99991 -14.34235 1.000 46.14739  ? 193 LEU A CD2 1 
ATOM   1214 N N   . LYS A 1 195 ? -46.87297 -119.32726 -14.38042 1.000 40.77315  ? 194 LYS A N   1 
ATOM   1215 C CA  . LYS A 1 195 ? -45.69256 -118.90374 -15.11555 1.000 45.11568  ? 194 LYS A CA  1 
ATOM   1216 C C   . LYS A 1 195 ? -44.47957 -119.62047 -14.54374 1.000 43.89717  ? 194 LYS A C   1 
ATOM   1217 O O   . LYS A 1 195 ? -44.53104 -120.20192 -13.45758 1.000 41.73657  ? 194 LYS A O   1 
ATOM   1218 C CB  . LYS A 1 195 ? -45.49807 -117.38150 -15.05541 1.000 45.56157  ? 194 LYS A CB  1 
ATOM   1219 C CG  . LYS A 1 195 ? -45.24357 -116.84272 -13.65887 1.000 45.13905  ? 194 LYS A CG  1 
ATOM   1220 C CD  . LYS A 1 195 ? -45.15150 -115.32573 -13.66414 1.000 46.45076  ? 194 LYS A CD  1 
ATOM   1221 C CE  . LYS A 1 195 ? -44.83617 -114.79138 -12.27797 1.000 46.99326  ? 194 LYS A CE  1 
ATOM   1222 N NZ  . LYS A 1 195 ? -44.72771 -113.30828 -12.26335 1.000 48.70407  ? 194 LYS A NZ  1 
ATOM   1223 N N   . ASP A 1 196 ? -43.38094 -119.57816 -15.29325 1.000 40.57067  ? 195 ASP A N   1 
ATOM   1224 C CA  . ASP A 1 196 ? -42.14863 -120.23282 -14.88147 1.000 41.87530  ? 195 ASP A CA  1 
ATOM   1225 C C   . ASP A 1 196 ? -41.17295 -119.28366 -14.20360 1.000 45.88065  ? 195 ASP A C   1 
ATOM   1226 O O   . ASP A 1 196 ? -40.14240 -119.73812 -13.69572 1.000 45.94807  ? 195 ASP A O   1 
ATOM   1227 C CB  . ASP A 1 196 ? -41.47074 -120.89459 -16.08914 1.000 45.82692  ? 195 ASP A CB  1 
ATOM   1228 C CG  . ASP A 1 196 ? -42.31933 -121.99267 -16.70265 1.000 49.10403  ? 195 ASP A CG  1 
ATOM   1229 O OD1 . ASP A 1 196 ? -43.00325 -122.71352 -15.94471 1.000 48.19779  ? 195 ASP A OD1 1 
ATOM   1230 O OD2 . ASP A 1 196 ? -42.30957 -122.13211 -17.94479 1.000 52.94226  ? 195 ASP A OD2 1 
ATOM   1231 N N   . THR A 1 197 ? -41.47260 -117.98843 -14.18109 1.000 44.89255  ? 196 THR A N   1 
ATOM   1232 C CA  . THR A 1 197 ? -40.62496 -117.00569 -13.53104 1.000 47.11829  ? 196 THR A CA  1 
ATOM   1233 C C   . THR A 1 197 ? -41.07762 -116.79910 -12.08761 1.000 50.84087  ? 196 THR A C   1 
ATOM   1234 O O   . THR A 1 197 ? -42.06681 -117.37459 -11.62711 1.000 49.07955  ? 196 THR A O   1 
ATOM   1235 C CB  . THR A 1 197 ? -40.64245 -115.69253 -14.30915 1.000 48.35491  ? 196 THR A CB  1 
ATOM   1236 O OG1 . THR A 1 197 ? -41.99915 -115.28282 -14.51856 1.000 47.46329  ? 196 THR A OG1 1 
ATOM   1237 C CG2 . THR A 1 197 ? -39.95801 -115.86867 -15.65772 1.000 49.95035  ? 196 THR A CG2 1 
ATOM   1238 N N   . VAL A 1 198 ? -40.35086 -115.95477 -11.36747 1.000 49.82504  ? 197 VAL A N   1 
ATOM   1239 C CA  . VAL A 1 198 ? -40.57626 -115.77721 -9.93923  1.000 48.08515  ? 197 VAL A CA  1 
ATOM   1240 C C   . VAL A 1 198 ? -41.82618 -114.93621 -9.71387  1.000 48.68553  ? 197 VAL A C   1 
ATOM   1241 O O   . VAL A 1 198 ? -42.11289 -113.99815 -10.46650 1.000 49.09233  ? 197 VAL A O   1 
ATOM   1242 C CB  . VAL A 1 198 ? -39.33639 -115.14399 -9.27968  1.000 54.95359  ? 197 VAL A CB  1 
ATOM   1243 C CG1 . VAL A 1 198 ? -39.07033 -113.75382 -9.84344  1.000 57.11213  ? 197 VAL A CG1 1 
ATOM   1244 C CG2 . VAL A 1 198 ? -39.49418 -115.09828 -7.76469  1.000 52.52752  ? 197 VAL A CG2 1 
ATOM   1245 N N   . TYR A 1 199 ? -42.59510 -115.29618 -8.68902  1.000 46.33262  ? 198 TYR A N   1 
ATOM   1246 C CA  . TYR A 1 199 ? -43.69976 -114.47491 -8.21613  1.000 47.90197  ? 198 TYR A CA  1 
ATOM   1247 C C   . TYR A 1 199 ? -43.21333 -113.57107 -7.09035  1.000 53.00309  ? 198 TYR A C   1 
ATOM   1248 O O   . TYR A 1 199 ? -42.42846 -113.99320 -6.23652  1.000 51.12976  ? 198 TYR A O   1 
ATOM   1249 C CB  . TYR A 1 199 ? -44.85607 -115.34084 -7.70994  1.000 43.80594  ? 198 TYR A CB  1 
ATOM   1250 C CG  . TYR A 1 199 ? -45.60155 -116.11766 -8.77232  1.000 46.49371  ? 198 TYR A CG  1 
ATOM   1251 C CD1 . TYR A 1 199 ? -45.14331 -117.35285 -9.21163  1.000 43.32401  ? 198 TYR A CD1 1 
ATOM   1252 C CD2 . TYR A 1 199 ? -46.77922 -115.62420 -9.31786  1.000 41.33668  ? 198 TYR A CD2 1 
ATOM   1253 C CE1 . TYR A 1 199 ? -45.83235 -118.06749 -10.17589 1.000 38.31925  ? 198 TYR A CE1 1 
ATOM   1254 C CE2 . TYR A 1 199 ? -47.47140 -116.32699 -10.27964 1.000 36.75673  ? 198 TYR A CE2 1 
ATOM   1255 C CZ  . TYR A 1 199 ? -46.99674 -117.55026 -10.70399 1.000 40.87036  ? 198 TYR A CZ  1 
ATOM   1256 O OH  . TYR A 1 199 ? -47.69090 -118.25236 -11.66643 1.000 38.09179  ? 198 TYR A OH  1 
ATOM   1257 N N   . THR A 1 200 ? -43.68272 -112.32330 -7.09334  1.000 54.21863  ? 199 THR A N   1 
ATOM   1258 C CA  . THR A 1 200 ? -43.37382 -111.37927 -6.02841  1.000 55.27410  ? 199 THR A CA  1 
ATOM   1259 C C   . THR A 1 200 ? -44.61269 -110.88786 -5.29538  1.000 55.83978  ? 199 THR A C   1 
ATOM   1260 O O   . THR A 1 200 ? -44.48120 -110.12072 -4.33488  1.000 58.47401  ? 199 THR A O   1 
ATOM   1261 C CB  . THR A 1 200 ? -42.59693 -110.17443 -6.57936  1.000 57.17998  ? 199 THR A CB  1 
ATOM   1262 O OG1 . THR A 1 200 ? -43.34089 -109.56555 -7.64213  1.000 58.99031  ? 199 THR A OG1 1 
ATOM   1263 C CG2 . THR A 1 200 ? -41.23571 -110.61081 -7.09915  1.000 51.49947  ? 199 THR A CG2 1 
ATOM   1264 N N   . ASP A 1 201 ? -45.80412 -111.29667 -5.72144  1.000 58.95672  ? 200 ASP A N   1 
ATOM   1265 C CA  . ASP A 1 201 ? -47.05025 -110.97589 -5.04394  1.000 59.40266  ? 200 ASP A CA  1 
ATOM   1266 C C   . ASP A 1 201 ? -47.66219 -112.24764 -4.47082  1.000 58.25405  ? 200 ASP A C   1 
ATOM   1267 O O   . ASP A 1 201 ? -47.43039 -113.34951 -4.97837  1.000 55.97549  ? 200 ASP A O   1 
ATOM   1268 C CB  . ASP A 1 201 ? -48.04642 -110.30832 -5.99840  1.000 60.82314  ? 200 ASP A CB  1 
ATOM   1269 C CG  . ASP A 1 201 ? -48.46533 -111.22358 -7.13757  1.000 65.27691  ? 200 ASP A CG  1 
ATOM   1270 O OD1 . ASP A 1 201 ? -47.58254 -111.88884 -7.72452  1.000 63.51197  ? 200 ASP A OD1 1 
ATOM   1271 O OD2 . ASP A 1 201 ? -49.67749 -111.28483 -7.44108  1.000 65.78737  ? 200 ASP A OD2 1 
ATOM   1272 N N   . PHE A 1 202 ? -48.45136 -112.08518 -3.40936  1.000 54.92252  ? 201 PHE A N   1 
ATOM   1273 C CA  . PHE A 1 202 ? -49.10249 -113.21825 -2.76335  1.000 53.46854  ? 201 PHE A CA  1 
ATOM   1274 C C   . PHE A 1 202 ? -50.26427 -112.70678 -1.92704  1.000 52.24625  ? 201 PHE A C   1 
ATOM   1275 O O   . PHE A 1 202 ? -50.09079 -111.78525 -1.12482  1.000 55.05311  ? 201 PHE A O   1 
ATOM   1276 C CB  . PHE A 1 202 ? -48.10955 -113.99573 -1.89088  1.000 52.35608  ? 201 PHE A CB  1 
ATOM   1277 C CG  . PHE A 1 202 ? -48.71416 -115.17021 -1.17559  1.000 49.68073  ? 201 PHE A CG  1 
ATOM   1278 C CD1 . PHE A 1 202 ? -48.97541 -116.35081 -1.85242  1.000 50.66483  ? 201 PHE A CD1 1 
ATOM   1279 C CD2 . PHE A 1 202 ? -49.00963 -115.09845 0.17676   1.000 49.16398  ? 201 PHE A CD2 1 
ATOM   1280 C CE1 . PHE A 1 202 ? -49.52738 -117.43679 -1.19579  1.000 49.22813  ? 201 PHE A CE1 1 
ATOM   1281 C CE2 . PHE A 1 202 ? -49.56212 -116.17938 0.83879   1.000 47.75942  ? 201 PHE A CE2 1 
ATOM   1282 C CZ  . PHE A 1 202 ? -49.81724 -117.35182 0.15205   1.000 46.35801  ? 201 PHE A CZ  1 
ATOM   1283 N N   . ASP A 1 203 ? -51.44442 -113.30505 -2.11772  1.000 51.89295  ? 202 ASP A N   1 
ATOM   1284 C CA  . ASP A 1 203 ? -52.62900 -112.95169 -1.34319  1.000 54.09298  ? 202 ASP A CA  1 
ATOM   1285 C C   . ASP A 1 203 ? -53.30582 -114.18168 -0.74501  1.000 51.47820  ? 202 ASP A C   1 
ATOM   1286 O O   . ASP A 1 203 ? -54.47609 -114.10882 -0.35475  1.000 55.72133  ? 202 ASP A O   1 
ATOM   1287 C CB  . ASP A 1 203 ? -53.62519 -112.16558 -2.20052  1.000 53.34514  ? 202 ASP A CB  1 
ATOM   1288 N N   . GLY A 1 204 ? -52.59802 -115.30842 -0.66632  1.000 49.96216  ? 203 GLY A N   1 
ATOM   1289 C CA  . GLY A 1 204 ? -53.13397 -116.52164 -0.07751  1.000 45.82771  ? 203 GLY A CA  1 
ATOM   1290 C C   . GLY A 1 204 ? -53.05068 -116.51970 1.43497   1.000 47.04090  ? 203 GLY A C   1 
ATOM   1291 O O   . GLY A 1 204 ? -53.06749 -115.46768 2.08240   1.000 47.26788  ? 203 GLY A O   1 
ATOM   1292 N N   . THR A 1 205 ? -52.95270 -117.71742 2.00901   1.000 42.52502  ? 204 THR A N   1 
ATOM   1293 C CA  . THR A 1 205 ? -52.95420 -117.90713 3.45522   1.000 43.08817  ? 204 THR A CA  1 
ATOM   1294 C C   . THR A 1 205 ? -51.52134 -118.06566 3.95079   1.000 40.90754  ? 204 THR A C   1 
ATOM   1295 O O   . THR A 1 205 ? -50.80446 -118.97079 3.50997   1.000 38.12367  ? 204 THR A O   1 
ATOM   1296 C CB  . THR A 1 205 ? -53.79367 -119.12355 3.84225   1.000 39.62510  ? 204 THR A CB  1 
ATOM   1297 O OG1 . THR A 1 205 ? -55.13221 -118.94321 3.36420   1.000 39.73228  ? 204 THR A OG1 1 
ATOM   1298 C CG2 . THR A 1 205 ? -53.82239 -119.28642 5.35757   1.000 41.25400  ? 204 THR A CG2 1 
ATOM   1299 N N   . ARG A 1 206 ? -51.12193 -117.20269 4.89071   1.000 40.58946  ? 205 ARG A N   1 
ATOM   1300 C CA  . ARG A 1 206 ? -49.71618 -117.11254 5.27902   1.000 42.80156  ? 205 ARG A CA  1 
ATOM   1301 C C   . ARG A 1 206 ? -49.21174 -118.39952 5.92777   1.000 42.61688  ? 205 ARG A C   1 
ATOM   1302 O O   . ARG A 1 206 ? -48.07204 -118.81349 5.68072   1.000 39.63855  ? 205 ARG A O   1 
ATOM   1303 C CB  . ARG A 1 206 ? -49.50750 -115.92415 6.21708   1.000 41.92881  ? 205 ARG A CB  1 
ATOM   1304 C CG  . ARG A 1 206 ? -48.05024 -115.63961 6.52824   1.000 44.17334  ? 205 ARG A CG  1 
ATOM   1305 C CD  . ARG A 1 206 ? -47.89426 -114.36834 7.34312   1.000 48.04676  ? 205 ARG A CD  1 
ATOM   1306 N NE  . ARG A 1 206 ? -46.49245 -114.01861 7.53506   1.000 50.46514  ? 205 ARG A NE  1 
ATOM   1307 C CZ  . ARG A 1 206 ? -45.78239 -113.28418 6.68956   1.000 53.07525  ? 205 ARG A CZ  1 
ATOM   1308 N NH1 . ARG A 1 206 ? -46.31072 -112.81020 5.57318   1.000 49.02277  ? 205 ARG A NH1 1 
ATOM   1309 N NH2 . ARG A 1 206 ? -44.51011 -113.01999 6.97056   1.000 55.01655  ? 205 ARG A NH2 1 
ATOM   1310 N N   . VAL A 1 207 ? -50.03202 -119.04683 6.76195   1.000 36.38822  ? 206 VAL A N   1 
ATOM   1311 C CA  . VAL A 1 207 ? -49.58151 -120.26371 7.43372   1.000 37.09519  ? 206 VAL A CA  1 
ATOM   1312 C C   . VAL A 1 207 ? -49.43172 -121.43803 6.47931   1.000 38.04628  ? 206 VAL A C   1 
ATOM   1313 O O   . VAL A 1 207 ? -48.87785 -122.47272 6.86877   1.000 38.29811  ? 206 VAL A O   1 
ATOM   1314 C CB  . VAL A 1 207 ? -50.51631 -120.65851 8.59898   1.000 39.91978  ? 206 VAL A CB  1 
ATOM   1315 C CG1 . VAL A 1 207 ? -50.35619 -119.68331 9.77984   1.000 38.37439  ? 206 VAL A CG1 1 
ATOM   1316 C CG2 . VAL A 1 207 ? -51.96273 -120.72870 8.14061   1.000 37.06035  ? 206 VAL A CG2 1 
ATOM   1317 N N   . TYR A 1 208 ? -49.90593 -121.30550 5.24140   1.000 36.89743  ? 207 TYR A N   1 
ATOM   1318 C CA  . TYR A 1 208 ? -49.66519 -122.28409 4.19101   1.000 36.69187  ? 207 TYR A CA  1 
ATOM   1319 C C   . TYR A 1 208 ? -48.59006 -121.84219 3.20877   1.000 36.92695  ? 207 TYR A C   1 
ATOM   1320 O O   . TYR A 1 208 ? -48.30121 -122.57799 2.26188   1.000 32.60658  ? 207 TYR A O   1 
ATOM   1321 C CB  . TYR A 1 208 ? -50.95915 -122.57041 3.41831   1.000 36.42536  ? 207 TYR A CB  1 
ATOM   1322 C CG  . TYR A 1 208 ? -51.93499 -123.49819 4.11307   1.000 35.40928  ? 207 TYR A CG  1 
ATOM   1323 C CD1 . TYR A 1 208 ? -52.75222 -123.04225 5.14351   1.000 32.37620  ? 207 TYR A CD1 1 
ATOM   1324 C CD2 . TYR A 1 208 ? -52.05686 -124.82533 3.71733   1.000 32.27671  ? 207 TYR A CD2 1 
ATOM   1325 C CE1 . TYR A 1 208 ? -53.65250 -123.89127 5.77566   1.000 34.56547  ? 207 TYR A CE1 1 
ATOM   1326 C CE2 . TYR A 1 208 ? -52.94917 -125.67921 4.34052   1.000 32.90929  ? 207 TYR A CE2 1 
ATOM   1327 C CZ  . TYR A 1 208 ? -53.74438 -125.20584 5.36709   1.000 30.99099  ? 207 TYR A CZ  1 
ATOM   1328 O OH  . TYR A 1 208 ? -54.63567 -126.05461 5.97097   1.000 31.92720  ? 207 TYR A OH  1 
ATOM   1329 N N   . SER A 1 209 ? -47.98716 -120.62881 3.40549   1.000 41.69097  ? 208 SER A N   1 
ATOM   1330 C CA  . SER A 1 209 ? -47.03222 -120.09271 2.44396   1.000 40.20766  ? 208 SER A CA  1 
ATOM   1331 C C   . SER A 1 209 ? -45.61878 -120.59132 2.74694   1.000 39.17132  ? 208 SER A C   1 
ATOM   1332 O O   . SER A 1 209 ? -45.28901 -120.88207 3.90143   1.000 40.03439  ? 208 SER A O   1 
ATOM   1333 C CB  . SER A 1 209 ? -47.06330 -118.56320 2.45845   1.000 41.29386  ? 208 SER A CB  1 
ATOM   1334 O OG  . SER A 1 209 ? -46.50807 -118.03965 3.65218   1.000 42.11966  ? 208 SER A OG  1 
ATOM   1335 N N   . PRO A 1 210 ? -44.76700 -120.70024 1.73001   1.000 41.14079  ? 209 PRO A N   1 
ATOM   1336 C CA  . PRO A 1 210 ? -43.46332 -121.34451 1.91239   1.000 40.66688  ? 209 PRO A CA  1 
ATOM   1337 C C   . PRO A 1 210 ? -42.46072 -120.39905 2.54784   1.000 42.38574  ? 209 PRO A C   1 
ATOM   1338 O O   . PRO A 1 210 ? -42.65047 -119.17330 2.52958   1.000 43.23220  ? 209 PRO A O   1 
ATOM   1339 C CB  . PRO A 1 210 ? -43.05863 -121.70323 0.47628   1.000 39.34513  ? 209 PRO A CB  1 
ATOM   1340 C CG  . PRO A 1 210 ? -43.66737 -120.61721 -0.33323  1.000 39.98089  ? 209 PRO A CG  1 
ATOM   1341 C CD  . PRO A 1 210 ? -44.99286 -120.32374 0.32148   1.000 39.59625  ? 209 PRO A CD  1 
ATOM   1342 N N   . PRO A 1 211 ? -41.36786 -120.92966 3.10632   1.000 43.54153  ? 210 PRO A N   1 
ATOM   1343 C CA  . PRO A 1 211 ? -40.39963 -120.05548 3.78903   1.000 43.81948  ? 210 PRO A CA  1 
ATOM   1344 C C   . PRO A 1 211 ? -39.72390 -119.05646 2.87027   1.000 46.91579  ? 210 PRO A C   1 
ATOM   1345 O O   . PRO A 1 211 ? -39.30785 -117.98978 3.33956   1.000 45.55382  ? 210 PRO A O   1 
ATOM   1346 C CB  . PRO A 1 211 ? -39.38896 -121.04815 4.38165   1.000 45.51980  ? 210 PRO A CB  1 
ATOM   1347 C CG  . PRO A 1 211 ? -39.52169 -122.27203 3.54098   1.000 43.20348  ? 210 PRO A CG  1 
ATOM   1348 C CD  . PRO A 1 211 ? -40.97052 -122.34568 3.16928   1.000 43.15218  ? 210 PRO A CD  1 
ATOM   1349 N N   . GLU A 1 212 ? -39.59646 -119.36143 1.57499   1.000 44.09876  ? 211 GLU A N   1 
ATOM   1350 C CA  . GLU A 1 212 ? -38.99340 -118.39468 0.66403   1.000 45.83737  ? 211 GLU A CA  1 
ATOM   1351 C C   . GLU A 1 212 ? -39.87160 -117.16165 0.49999   1.000 47.56506  ? 211 GLU A C   1 
ATOM   1352 O O   . GLU A 1 212 ? -39.36151 -116.07747 0.20041   1.000 50.89987  ? 211 GLU A O   1 
ATOM   1353 C CB  . GLU A 1 212 ? -38.70912 -119.03867 -0.69587  1.000 43.36904  ? 211 GLU A CB  1 
ATOM   1354 C CG  . GLU A 1 212 ? -39.93351 -119.58210 -1.42284  1.000 43.40764  ? 211 GLU A CG  1 
ATOM   1355 C CD  . GLU A 1 212 ? -40.17183 -121.05482 -1.15489  1.000 43.41208  ? 211 GLU A CD  1 
ATOM   1356 O OE1 . GLU A 1 212 ? -39.76104 -121.54500 -0.08039  1.000 42.34956  ? 211 GLU A OE1 1 
ATOM   1357 O OE2 . GLU A 1 212 ? -40.76631 -121.72565 -2.02620  1.000 41.94148  ? 211 GLU A OE2 1 
ATOM   1358 N N   . TRP A 1 213 ? -41.18575 -117.30242 0.68762   1.000 46.84745  ? 212 TRP A N   1 
ATOM   1359 C CA  . TRP A 1 213 ? -42.05367 -116.12997 0.69950   1.000 48.22906  ? 212 TRP A CA  1 
ATOM   1360 C C   . TRP A 1 213 ? -41.90314 -115.34517 1.99679   1.000 51.02729  ? 212 TRP A C   1 
ATOM   1361 O O   . TRP A 1 213 ? -41.83873 -114.11009 1.97360   1.000 52.27205  ? 212 TRP A O   1 
ATOM   1362 C CB  . TRP A 1 213 ? -43.51494 -116.53639 0.49433   1.000 45.85960  ? 212 TRP A CB  1 
ATOM   1363 C CG  . TRP A 1 213 ? -44.47370 -115.44279 0.86442   1.000 47.38268  ? 212 TRP A CG  1 
ATOM   1364 C CD1 . TRP A 1 213 ? -45.28330 -115.39805 1.96171   1.000 49.15118  ? 212 TRP A CD1 1 
ATOM   1365 C CD2 . TRP A 1 213 ? -44.70111 -114.22188 0.14795   1.000 49.29679  ? 212 TRP A CD2 1 
ATOM   1366 N NE1 . TRP A 1 213 ? -46.00850 -114.23013 1.96719   1.000 50.75673  ? 212 TRP A NE1 1 
ATOM   1367 C CE2 . TRP A 1 213 ? -45.66909 -113.49156 0.86374   1.000 50.40471  ? 212 TRP A CE2 1 
ATOM   1368 C CE3 . TRP A 1 213 ? -44.18869 -113.68217 -1.03669  1.000 54.51538  ? 212 TRP A CE3 1 
ATOM   1369 C CZ2 . TRP A 1 213 ? -46.13006 -112.24735 0.43859   1.000 53.37790  ? 212 TRP A CZ2 1 
ATOM   1370 C CZ3 . TRP A 1 213 ? -44.64692 -112.44520 -1.45670  1.000 52.36264  ? 212 TRP A CZ3 1 
ATOM   1371 C CH2 . TRP A 1 213 ? -45.60788 -111.74288 -0.72121  1.000 53.46221  ? 212 TRP A CH2 1 
ATOM   1372 N N   . ILE A 1 214 ? -41.84620 -116.04706 3.13258   1.000 50.27149  ? 213 ILE A N   1 
ATOM   1373 C CA  . ILE A 1 214 ? -41.69371 -115.37906 4.42326   1.000 46.19613  ? 213 ILE A CA  1 
ATOM   1374 C C   . ILE A 1 214 ? -40.39437 -114.58182 4.46616   1.000 51.25774  ? 213 ILE A C   1 
ATOM   1375 O O   . ILE A 1 214 ? -40.36543 -113.43848 4.93709   1.000 54.47812  ? 213 ILE A O   1 
ATOM   1376 C CB  . ILE A 1 214 ? -41.75877 -116.40951 5.56709   1.000 45.58108  ? 213 ILE A CB  1 
ATOM   1377 C CG1 . ILE A 1 214 ? -43.06175 -117.21276 5.51179   1.000 45.77069  ? 213 ILE A CG1 1 
ATOM   1378 C CG2 . ILE A 1 214 ? -41.58944 -115.72174 6.92066   1.000 51.36064  ? 213 ILE A CG2 1 
ATOM   1379 C CD1 . ILE A 1 214 ? -44.31222 -116.40354 5.79067   1.000 47.87356  ? 213 ILE A CD1 1 
ATOM   1380 N N   . ARG A 1 215 ? -39.30239 -115.16374 3.96428   1.000 51.59221  ? 214 ARG A N   1 
ATOM   1381 C CA  . ARG A 1 215 ? -37.99216 -114.53114 4.09331   1.000 54.21433  ? 214 ARG A CA  1 
ATOM   1382 C C   . ARG A 1 215 ? -37.75127 -113.48411 3.01102   1.000 57.18558  ? 214 ARG A C   1 
ATOM   1383 O O   . ARG A 1 215 ? -37.35532 -112.35343 3.31308   1.000 59.32898  ? 214 ARG A O   1 
ATOM   1384 C CB  . ARG A 1 215 ? -36.88512 -115.58861 4.05442   1.000 57.92764  ? 214 ARG A CB  1 
ATOM   1385 C CG  . ARG A 1 215 ? -36.76114 -116.42552 5.31802   1.000 59.20466  ? 214 ARG A CG  1 
ATOM   1386 C CD  . ARG A 1 215 ? -35.53274 -117.32463 5.25848   1.000 58.84560  ? 214 ARG A CD  1 
ATOM   1387 N N   . TYR A 1 216 ? -37.97605 -113.84011 1.74475   1.000 54.03477  ? 215 TYR A N   1 
ATOM   1388 C CA  . TYR A 1 216 ? -37.54486 -113.01066 0.62777   1.000 57.92367  ? 215 TYR A CA  1 
ATOM   1389 C C   . TYR A 1 216 ? -38.68135 -112.43553 -0.20606  1.000 55.50356  ? 215 TYR A C   1 
ATOM   1390 O O   . TYR A 1 216 ? -38.40645 -111.71804 -1.17525  1.000 57.55704  ? 215 TYR A O   1 
ATOM   1391 C CB  . TYR A 1 216 ? -36.61261 -113.81133 -0.29266  1.000 56.87597  ? 215 TYR A CB  1 
ATOM   1392 C CG  . TYR A 1 216 ? -35.57250 -114.62684 0.44228   1.000 63.16644  ? 215 TYR A CG  1 
ATOM   1393 C CD1 . TYR A 1 216 ? -34.55315 -114.00995 1.15696   1.000 65.36416  ? 215 TYR A CD1 1 
ATOM   1394 C CD2 . TYR A 1 216 ? -35.60378 -116.01478 0.41195   1.000 61.95984  ? 215 TYR A CD2 1 
ATOM   1395 C CE1 . TYR A 1 216 ? -33.59837 -114.75396 1.82689   1.000 65.17744  ? 215 TYR A CE1 1 
ATOM   1396 C CE2 . TYR A 1 216 ? -34.65376 -116.76610 1.07790   1.000 64.41394  ? 215 TYR A CE2 1 
ATOM   1397 C CZ  . TYR A 1 216 ? -33.65529 -116.13172 1.78373   1.000 67.84233  ? 215 TYR A CZ  1 
ATOM   1398 O OH  . TYR A 1 216 ? -32.70895 -116.87938 2.44608   1.000 79.00524  ? 215 TYR A OH  1 
ATOM   1399 N N   . HIS A 1 217 ? -39.93920 -112.72515 0.13025   1.000 54.66334  ? 216 HIS A N   1 
ATOM   1400 C CA  . HIS A 1 217 ? -41.08489 -112.28746 -0.67102  1.000 56.10390  ? 216 HIS A CA  1 
ATOM   1401 C C   . HIS A 1 217 ? -40.95602 -112.74116 -2.12522  1.000 53.73603  ? 216 HIS A C   1 
ATOM   1402 O O   . HIS A 1 217 ? -41.33629 -112.02594 -3.05410  1.000 53.08881  ? 216 HIS A O   1 
ATOM   1403 C CB  . HIS A 1 217 ? -41.27922 -110.77011 -0.59143  1.000 55.13006  ? 216 HIS A CB  1 
ATOM   1404 C CG  . HIS A 1 217 ? -42.18500 -110.33492 0.51775   1.000 62.71278  ? 216 HIS A CG  1 
ATOM   1405 N ND1 . HIS A 1 217 ? -42.88175 -109.14588 0.48669   1.000 66.03636  ? 216 HIS A ND1 1 
ATOM   1406 C CD2 . HIS A 1 217 ? -42.51140 -110.93158 1.68903   1.000 63.76942  ? 216 HIS A CD2 1 
ATOM   1407 C CE1 . HIS A 1 217 ? -43.59649 -109.02780 1.59201   1.000 69.54845  ? 216 HIS A CE1 1 
ATOM   1408 N NE2 . HIS A 1 217 ? -43.38887 -110.09752 2.33894   1.000 66.88682  ? 216 HIS A NE2 1 
ATOM   1409 N N   . ARG A 1 218 ? -40.41591 -113.94292 -2.32351  1.000 54.67831  ? 217 ARG A N   1 
ATOM   1410 C CA  . ARG A 1 218 ? -40.24122 -114.52260 -3.64793  1.000 52.44912  ? 217 ARG A CA  1 
ATOM   1411 C C   . ARG A 1 218 ? -40.58341 -116.00217 -3.59754  1.000 47.25860  ? 217 ARG A C   1 
ATOM   1412 O O   . ARG A 1 218 ? -40.30994 -116.67272 -2.59871  1.000 51.13012  ? 217 ARG A O   1 
ATOM   1413 C CB  . ARG A 1 218 ? -38.80417 -114.35143 -4.15619  1.000 52.07686  ? 217 ARG A CB  1 
ATOM   1414 C CG  . ARG A 1 218 ? -38.42691 -112.93353 -4.53411  1.000 59.60348  ? 217 ARG A CG  1 
ATOM   1415 C CD  . ARG A 1 218 ? -36.91906 -112.79734 -4.67152  1.000 62.17899  ? 217 ARG A CD  1 
ATOM   1416 N NE  . ARG A 1 218 ? -36.34964 -113.82455 -5.53586  1.000 68.89647  ? 217 ARG A NE  1 
ATOM   1417 C CZ  . ARG A 1 218 ? -36.05412 -113.64748 -6.81684  1.000 72.80658  ? 217 ARG A CZ  1 
ATOM   1418 N NH1 . ARG A 1 218 ? -36.26523 -112.48929 -7.42196  1.000 72.47669  ? 217 ARG A NH1 1 
ATOM   1419 N NH2 . ARG A 1 218 ? -35.53007 -114.65645 -7.50744  1.000 69.48390  ? 217 ARG A NH2 1 
ATOM   1420 N N   . TYR A 1 219 ? -41.17015 -116.50798 -4.68041  1.000 46.79722  ? 218 TYR A N   1 
ATOM   1421 C CA  . TYR A 1 219 ? -41.45568 -117.93145 -4.79194  1.000 44.51871  ? 218 TYR A CA  1 
ATOM   1422 C C   . TYR A 1 219 ? -41.75444 -118.26416 -6.24501  1.000 46.59242  ? 218 TYR A C   1 
ATOM   1423 O O   . TYR A 1 219 ? -42.16144 -117.40353 -7.02960  1.000 46.82765  ? 218 TYR A O   1 
ATOM   1424 C CB  . TYR A 1 219 ? -42.62951 -118.35104 -3.89376  1.000 41.80284  ? 218 TYR A CB  1 
ATOM   1425 C CG  . TYR A 1 219 ? -43.94800 -117.69695 -4.25003  1.000 45.75111  ? 218 TYR A CG  1 
ATOM   1426 C CD1 . TYR A 1 219 ? -44.29648 -116.46005 -3.72050  1.000 43.15423  ? 218 TYR A CD1 1 
ATOM   1427 C CD2 . TYR A 1 219 ? -44.84558 -118.31752 -5.11410  1.000 40.88037  ? 218 TYR A CD2 1 
ATOM   1428 C CE1 . TYR A 1 219 ? -45.49895 -115.85771 -4.04248  1.000 44.84563  ? 218 TYR A CE1 1 
ATOM   1429 C CE2 . TYR A 1 219 ? -46.05217 -117.72309 -5.44081  1.000 41.72824  ? 218 TYR A CE2 1 
ATOM   1430 C CZ  . TYR A 1 219 ? -46.37204 -116.49299 -4.90274  1.000 45.39178  ? 218 TYR A CZ  1 
ATOM   1431 O OH  . TYR A 1 219 ? -47.56740 -115.89464 -5.22631  1.000 44.86906  ? 218 TYR A OH  1 
ATOM   1432 N N   . HIS A 1 220 ? -41.53974 -119.52779 -6.59195  1.000 45.68770  ? 219 HIS A N   1 
ATOM   1433 C CA  . HIS A 1 220 ? -41.98959 -120.07197 -7.86148  1.000 43.11936  ? 219 HIS A CA  1 
ATOM   1434 C C   . HIS A 1 220 ? -43.25263 -120.89227 -7.63433  1.000 40.06479  ? 219 HIS A C   1 
ATOM   1435 O O   . HIS A 1 220 ? -43.46413 -121.45034 -6.55530  1.000 38.05381  ? 219 HIS A O   1 
ATOM   1436 C CB  . HIS A 1 220 ? -40.89753 -120.91862 -8.51716  1.000 43.36852  ? 219 HIS A CB  1 
ATOM   1437 C CG  . HIS A 1 220 ? -39.72629 -120.11552 -8.98942  1.000 45.73183  ? 219 HIS A CG  1 
ATOM   1438 N ND1 . HIS A 1 220 ? -38.77607 -119.61061 -8.12845  1.000 45.27317  ? 219 HIS A ND1 1 
ATOM   1439 C CD2 . HIS A 1 220 ? -39.36701 -119.70433 -10.22895 1.000 47.33301  ? 219 HIS A CD2 1 
ATOM   1440 C CE1 . HIS A 1 220 ? -37.87271 -118.93650 -8.81817  1.000 47.58803  ? 219 HIS A CE1 1 
ATOM   1441 N NE2 . HIS A 1 220 ? -38.20861 -118.97691 -10.09520 1.000 48.29120  ? 219 HIS A NE2 1 
ATOM   1442 N N   . GLY A 1 221 ? -44.09101 -120.95707 -8.67009  1.000 35.85500  ? 220 GLY A N   1 
ATOM   1443 C CA  . GLY A 1 221 ? -45.45522 -121.42781 -8.48274  1.000 38.02013  ? 220 GLY A CA  1 
ATOM   1444 C C   . GLY A 1 221 ? -45.54093 -122.87416 -8.03445  1.000 39.34852  ? 220 GLY A C   1 
ATOM   1445 O O   . GLY A 1 221 ? -46.23828 -123.19736 -7.07169  1.000 35.58735  ? 220 GLY A O   1 
ATOM   1446 N N   . ARG A 1 222 ? -44.83860 -123.76607 -8.73130  1.000 37.37172  ? 221 ARG A N   1 
ATOM   1447 C CA  . ARG A 1 222 ? -44.99045 -125.19266 -8.46511  1.000 36.51331  ? 221 ARG A CA  1 
ATOM   1448 C C   . ARG A 1 222 ? -44.40671 -125.57302 -7.11062  1.000 36.98822  ? 221 ARG A C   1 
ATOM   1449 O O   . ARG A 1 222 ? -45.02946 -126.31801 -6.34463  1.000 35.75573  ? 221 ARG A O   1 
ATOM   1450 C CB  . ARG A 1 222 ? -44.34029 -126.00061 -9.58616  1.000 38.57047  ? 221 ARG A CB  1 
ATOM   1451 C CG  . ARG A 1 222 ? -44.95795 -125.72459 -10.94445 1.000 42.24071  ? 221 ARG A CG  1 
ATOM   1452 C CD  . ARG A 1 222 ? -44.14211 -126.33377 -12.07178 1.000 48.62583  ? 221 ARG A CD  1 
ATOM   1453 N NE  . ARG A 1 222 ? -44.72761 -126.04475 -13.37651 1.000 50.69712  ? 221 ARG A NE  1 
ATOM   1454 C CZ  . ARG A 1 222 ? -44.44136 -124.97357 -14.10565 1.000 54.69134  ? 221 ARG A CZ  1 
ATOM   1455 N NH1 . ARG A 1 222 ? -43.58728 -124.05350 -13.68094 1.000 52.18765  ? 221 ARG A NH1 1 
ATOM   1456 N NH2 . ARG A 1 222 ? -45.01892 -124.82489 -15.29494 1.000 54.19235  ? 221 ARG A NH2 1 
ATOM   1457 N N   . SER A 1 223 ? -43.20889 -125.07489 -6.79544  1.000 37.04102  ? 222 SER A N   1 
ATOM   1458 C CA  . SER A 1 223 ? -42.59678 -125.42356 -5.51876  1.000 37.78994  ? 222 SER A CA  1 
ATOM   1459 C C   . SER A 1 223 ? -43.36718 -124.82533 -4.34818  1.000 36.62171  ? 222 SER A C   1 
ATOM   1460 O O   . SER A 1 223 ? -43.41367 -125.42512 -3.26787  1.000 38.60109  ? 222 SER A O   1 
ATOM   1461 C CB  . SER A 1 223 ? -41.13300 -124.97736 -5.49482  1.000 39.01852  ? 222 SER A CB  1 
ATOM   1462 O OG  . SER A 1 223 ? -41.00459 -123.60530 -5.81903  1.000 43.90547  ? 222 SER A OG  1 
ATOM   1463 N N   . ALA A 1 224 ? -43.98415 -123.65720 -4.54183  1.000 36.02337  ? 223 ALA A N   1 
ATOM   1464 C CA  . ALA A 1 224 ? -44.82752 -123.08875 -3.49622  1.000 37.86668  ? 223 ALA A CA  1 
ATOM   1465 C C   . ALA A 1 224 ? -46.08903 -123.91810 -3.29801  1.000 37.76087  ? 223 ALA A C   1 
ATOM   1466 O O   . ALA A 1 224 ? -46.54362 -124.10396 -2.16339  1.000 35.62695  ? 223 ALA A O   1 
ATOM   1467 C CB  . ALA A 1 224 ? -45.18710 -121.64221 -3.83325  1.000 39.55698  ? 223 ALA A CB  1 
ATOM   1468 N N   . ALA A 1 225 ? -46.67028 -124.42205 -4.39141  1.000 36.62228  ? 224 ALA A N   1 
ATOM   1469 C CA  . ALA A 1 225 ? -47.84980 -125.27334 -4.27289  1.000 35.31882  ? 224 ALA A CA  1 
ATOM   1470 C C   . ALA A 1 225 ? -47.52646 -126.55386 -3.51496  1.000 35.18852  ? 224 ALA A C   1 
ATOM   1471 O O   . ALA A 1 225 ? -48.31882 -127.00782 -2.68109  1.000 32.84117  ? 224 ALA A O   1 
ATOM   1472 C CB  . ALA A 1 225 ? -48.40979 -125.59521 -5.66013  1.000 33.13589  ? 224 ALA A CB  1 
ATOM   1473 N N   . VAL A 1 226 ? -46.35798 -127.14212 -3.78423  1.000 34.16031  ? 225 VAL A N   1 
ATOM   1474 C CA  . VAL A 1 226 ? -45.96535 -128.37954 -3.11489  1.000 33.84197  ? 225 VAL A CA  1 
ATOM   1475 C C   . VAL A 1 226 ? -45.80495 -128.15217 -1.61481  1.000 35.17801  ? 225 VAL A C   1 
ATOM   1476 O O   . VAL A 1 226 ? -46.18192 -129.00401 -0.79995  1.000 33.19836  ? 225 VAL A O   1 
ATOM   1477 C CB  . VAL A 1 226 ? -44.68042 -128.93897 -3.75635  1.000 36.16346  ? 225 VAL A CB  1 
ATOM   1478 C CG1 . VAL A 1 226 ? -44.10560 -130.07724 -2.92665  1.000 34.01274  ? 225 VAL A CG1 1 
ATOM   1479 C CG2 . VAL A 1 226 ? -44.96963 -129.40780 -5.18288  1.000 37.86953  ? 225 VAL A CG2 1 
ATOM   1480 N N   . TRP A 1 227 ? -45.25643 -126.99852 -1.22364  1.000 32.59529  ? 226 TRP A N   1 
ATOM   1481 C CA  . TRP A 1 227 ? -45.15247 -126.68149 0.19870   1.000 35.18247  ? 226 TRP A CA  1 
ATOM   1482 C C   . TRP A 1 227 ? -46.52796 -126.64780 0.85283   1.000 33.71953  ? 226 TRP A C   1 
ATOM   1483 O O   . TRP A 1 227 ? -46.73393 -127.23488 1.92277   1.000 35.27552  ? 226 TRP A O   1 
ATOM   1484 C CB  . TRP A 1 227 ? -44.43212 -125.34703 0.40556   1.000 34.56484  ? 226 TRP A CB  1 
ATOM   1485 C CG  . TRP A 1 227 ? -44.42206 -124.91333 1.85189   1.000 36.17158  ? 226 TRP A CG  1 
ATOM   1486 C CD1 . TRP A 1 227 ? -45.41826 -124.25510 2.52031   1.000 36.48486  ? 226 TRP A CD1 1 
ATOM   1487 C CD2 . TRP A 1 227 ? -43.37167 -125.12333 2.80720   1.000 36.35123  ? 226 TRP A CD2 1 
ATOM   1488 N NE1 . TRP A 1 227 ? -45.05187 -124.04388 3.82914   1.000 38.37580  ? 226 TRP A NE1 1 
ATOM   1489 C CE2 . TRP A 1 227 ? -43.80024 -124.56439 4.03046   1.000 36.64676  ? 226 TRP A CE2 1 
ATOM   1490 C CE3 . TRP A 1 227 ? -42.10961 -125.72366 2.74549   1.000 37.43211  ? 226 TRP A CE3 1 
ATOM   1491 C CZ2 . TRP A 1 227 ? -43.00990 -124.58660 5.18343   1.000 40.46893  ? 226 TRP A CZ2 1 
ATOM   1492 C CZ3 . TRP A 1 227 ? -41.32508 -125.74456 3.89365   1.000 38.99559  ? 226 TRP A CZ3 1 
ATOM   1493 C CH2 . TRP A 1 227 ? -41.78143 -125.18239 5.09536   1.000 38.54057  ? 226 TRP A CH2 1 
ATOM   1494 N N   . SER A 1 228 ? -47.48540 -125.95661 0.22648   1.000 33.33177  ? 227 SER A N   1 
ATOM   1495 C CA  . SER A 1 228 ? -48.82429 -125.88579 0.80347   1.000 32.72887  ? 227 SER A CA  1 
ATOM   1496 C C   . SER A 1 228 ? -49.46685 -127.26277 0.87335   1.000 32.24277  ? 227 SER A C   1 
ATOM   1497 O O   . SER A 1 228 ? -50.25929 -127.53339 1.78365   1.000 30.46930  ? 227 SER A O   1 
ATOM   1498 C CB  . SER A 1 228 ? -49.70277 -124.92722 -0.00261  1.000 32.69687  ? 227 SER A CB  1 
ATOM   1499 O OG  . SER A 1 228 ? -49.99201 -125.45749 -1.28768  1.000 36.41659  ? 227 SER A OG  1 
ATOM   1500 N N   . LEU A 1 229 ? -49.13169 -128.14362 -0.07487  1.000 29.75999  ? 228 LEU A N   1 
ATOM   1501 C CA  . LEU A 1 229 ? -49.62368 -129.51539 -0.03338  1.000 31.12981  ? 228 LEU A CA  1 
ATOM   1502 C C   . LEU A 1 229 ? -49.02901 -130.28887 1.13622   1.000 30.88871  ? 228 LEU A C   1 
ATOM   1503 O O   . LEU A 1 229 ? -49.70609 -131.14313 1.72061   1.000 32.72718  ? 228 LEU A O   1 
ATOM   1504 C CB  . LEU A 1 229 ? -49.31691 -130.21894 -1.35512  1.000 30.72982  ? 228 LEU A CB  1 
ATOM   1505 C CG  . LEU A 1 229 ? -50.14078 -129.73380 -2.54981  1.000 33.29924  ? 228 LEU A CG  1 
ATOM   1506 C CD1 . LEU A 1 229 ? -49.56193 -130.25322 -3.86569  1.000 36.21046  ? 228 LEU A CD1 1 
ATOM   1507 C CD2 . LEU A 1 229 ? -51.59060 -130.16808 -2.38926  1.000 31.34504  ? 228 LEU A CD2 1 
ATOM   1508 N N   . GLY A 1 230 ? -47.76971 -130.01549 1.48277   1.000 30.35350  ? 229 GLY A N   1 
ATOM   1509 C CA  . GLY A 1 230 ? -47.19483 -130.62277 2.67170   1.000 33.81051  ? 229 GLY A CA  1 
ATOM   1510 C C   . GLY A 1 230 ? -47.88250 -130.16387 3.94425   1.000 31.77291  ? 229 GLY A C   1 
ATOM   1511 O O   . GLY A 1 230 ? -48.15459 -130.97102 4.83860   1.000 30.26401  ? 229 GLY A O   1 
ATOM   1512 N N   . ILE A 1 231 ? -48.18131 -128.86445 4.03719   1.000 30.48916  ? 230 ILE A N   1 
ATOM   1513 C CA  . ILE A 1 231 ? -48.96039 -128.34961 5.16040   1.000 33.53070  ? 230 ILE A CA  1 
ATOM   1514 C C   . ILE A 1 231 ? -50.31919 -129.03049 5.21321   1.000 35.47200  ? 230 ILE A C   1 
ATOM   1515 O O   . ILE A 1 231 ? -50.79039 -129.43338 6.28474   1.000 32.59756  ? 230 ILE A O   1 
ATOM   1516 C CB  . ILE A 1 231 ? -49.10942 -126.81956 5.05480   1.000 32.67555  ? 230 ILE A CB  1 
ATOM   1517 C CG1 . ILE A 1 231 ? -47.73811 -126.13441 5.03335   1.000 36.29626  ? 230 ILE A CG1 1 
ATOM   1518 C CG2 . ILE A 1 231 ? -49.97350 -126.29059 6.19766   1.000 31.82498  ? 230 ILE A CG2 1 
ATOM   1519 C CD1 . ILE A 1 231 ? -46.92212 -126.34026 6.29373   1.000 32.88592  ? 230 ILE A CD1 1 
ATOM   1520 N N   . LEU A 1 232 ? -50.96443 -129.17414 4.05051   1.000 31.06267  ? 231 LEU A N   1 
ATOM   1521 C CA  . LEU A 1 232 ? -52.27905 -129.80138 3.98660   1.000 30.32538  ? 231 LEU A CA  1 
ATOM   1522 C C   . LEU A 1 232 ? -52.22659 -131.25699 4.43205   1.000 30.76051  ? 231 LEU A C   1 
ATOM   1523 O O   . LEU A 1 232 ? -53.12331 -131.72956 5.14028   1.000 31.71197  ? 231 LEU A O   1 
ATOM   1524 C CB  . LEU A 1 232 ? -52.82955 -129.70088 2.56378   1.000 28.41178  ? 231 LEU A CB  1 
ATOM   1525 C CG  . LEU A 1 232 ? -54.15980 -130.40368 2.30157   1.000 31.90426  ? 231 LEU A CG  1 
ATOM   1526 C CD1 . LEU A 1 232 ? -55.25714 -129.79591 3.15380   1.000 27.01324  ? 231 LEU A CD1 1 
ATOM   1527 C CD2 . LEU A 1 232 ? -54.52610 -130.33790 0.81371   1.000 30.12079  ? 231 LEU A CD2 1 
ATOM   1528 N N   . LEU A 1 233 ? -51.18877 -131.98800 4.02002   1.000 32.09246  ? 232 LEU A N   1 
ATOM   1529 C CA  . LEU A 1 233 ? -51.11411 -133.40329 4.36320   1.000 31.18965  ? 232 LEU A CA  1 
ATOM   1530 C C   . LEU A 1 233 ? -50.87172 -133.59758 5.85658   1.000 32.80270  ? 232 LEU A C   1 
ATOM   1531 O O   . LEU A 1 233 ? -51.50666 -134.45257 6.48642   1.000 33.76318  ? 232 LEU A O   1 
ATOM   1532 C CB  . LEU A 1 233 ? -50.02691 -134.08550 3.53237   1.000 30.48709  ? 232 LEU A CB  1 
ATOM   1533 C CG  . LEU A 1 233 ? -49.79776 -135.57419 3.81167   1.000 33.26661  ? 232 LEU A CG  1 
ATOM   1534 C CD1 . LEU A 1 233 ? -51.10333 -136.35842 3.77598   1.000 33.86670  ? 232 LEU A CD1 1 
ATOM   1535 C CD2 . LEU A 1 233 ? -48.79528 -136.14480 2.81884   1.000 30.77881  ? 232 LEU A CD2 1 
ATOM   1536 N N   . TYR A 1 234 ? -49.96118 -132.81437 6.44101   1.000 31.63142  ? 233 TYR A N   1 
ATOM   1537 C CA  . TYR A 1 234 ? -49.79546 -132.83438 7.89156   1.000 31.74852  ? 233 TYR A CA  1 
ATOM   1538 C C   . TYR A 1 234 ? -51.11483 -132.52049 8.58781   1.000 34.01455  ? 233 TYR A C   1 
ATOM   1539 O O   . TYR A 1 234 ? -51.48385 -133.17774 9.56772   1.000 34.34811  ? 233 TYR A O   1 
ATOM   1540 C CB  . TYR A 1 234 ? -48.71337 -131.83286 8.31126   1.000 32.07409  ? 233 TYR A CB  1 
ATOM   1541 C CG  . TYR A 1 234 ? -48.39083 -131.84048 9.79920   1.000 34.26491  ? 233 TYR A CG  1 
ATOM   1542 C CD1 . TYR A 1 234 ? -49.23102 -131.21923 10.71806  1.000 35.59296  ? 233 TYR A CD1 1 
ATOM   1543 C CD2 . TYR A 1 234 ? -47.24190 -132.45991 10.28127  1.000 32.01788  ? 233 TYR A CD2 1 
ATOM   1544 C CE1 . TYR A 1 234 ? -48.95057 -131.22879 12.07391  1.000 35.77538  ? 233 TYR A CE1 1 
ATOM   1545 C CE2 . TYR A 1 234 ? -46.94775 -132.47061 11.64389  1.000 36.42275  ? 233 TYR A CE2 1 
ATOM   1546 C CZ  . TYR A 1 234 ? -47.81092 -131.85434 12.53143  1.000 38.12677  ? 233 TYR A CZ  1 
ATOM   1547 O OH  . TYR A 1 234 ? -47.53975 -131.84872 13.88215  1.000 38.97816  ? 233 TYR A OH  1 
ATOM   1548 N N   . ASP A 1 235 ? -51.83567 -131.51495 8.08536   1.000 33.60362  ? 234 ASP A N   1 
ATOM   1549 C CA  . ASP A 1 235 ? -53.12022 -131.12284 8.65840   1.000 30.93328  ? 234 ASP A CA  1 
ATOM   1550 C C   . ASP A 1 235 ? -54.09410 -132.29671 8.69956   1.000 35.36684  ? 234 ASP A C   1 
ATOM   1551 O O   . ASP A 1 235 ? -54.78547 -132.50702 9.70564   1.000 32.82137  ? 234 ASP A O   1 
ATOM   1552 C CB  . ASP A 1 235 ? -53.67931 -129.94975 7.84367   1.000 32.38293  ? 234 ASP A CB  1 
ATOM   1553 C CG  . ASP A 1 235 ? -55.07236 -129.53516 8.26335   1.000 35.48901  ? 234 ASP A CG  1 
ATOM   1554 O OD1 . ASP A 1 235 ? -55.30852 -129.31031 9.47280   1.000 36.63039  ? 234 ASP A OD1 1 
ATOM   1555 O OD2 . ASP A 1 235 ? -55.93233 -129.40472 7.36458   1.000 32.13358  ? 234 ASP A OD2 1 
ATOM   1556 N N   . MET A 1 236 ? -54.13188 -133.09761 7.63098   1.000 30.62408  ? 235 MET A N   1 
ATOM   1557 C CA  . MET A 1 236 ? -55.06817 -134.21627 7.57330   1.000 33.22080  ? 235 MET A CA  1 
ATOM   1558 C C   . MET A 1 236 ? -54.69454 -135.32829 8.54811   1.000 34.02233  ? 235 MET A C   1 
ATOM   1559 O O   . MET A 1 236 ? -55.56946 -135.88593 9.21852   1.000 34.20420  ? 235 MET A O   1 
ATOM   1560 C CB  . MET A 1 236 ? -55.14241 -134.76762 6.15091   1.000 31.28639  ? 235 MET A CB  1 
ATOM   1561 C CG  . MET A 1 236 ? -55.93480 -133.89450 5.19038   1.000 33.71469  ? 235 MET A CG  1 
ATOM   1562 S SD  . MET A 1 236 ? -56.21536 -134.74744 3.62915   1.000 43.53088  ? 235 MET A SD  1 
ATOM   1563 C CE  . MET A 1 236 ? -54.53437 -135.00196 3.10926   1.000 31.24091  ? 235 MET A CE  1 
ATOM   1564 N N   . VAL A 1 237 ? -53.40963 -135.68968 8.62782   1.000 30.74042  ? 236 VAL A N   1 
ATOM   1565 C CA  . VAL A 1 237 ? -53.02569 -136.84445 9.44077   1.000 35.16717  ? 236 VAL A CA  1 
ATOM   1566 C C   . VAL A 1 237 ? -52.73766 -136.49203 10.89471  1.000 35.71888  ? 236 VAL A C   1 
ATOM   1567 O O   . VAL A 1 237 ? -52.64477 -137.40327 11.73180  1.000 37.96215  ? 236 VAL A O   1 
ATOM   1568 C CB  . VAL A 1 237 ? -51.80816 -137.58288 8.84330   1.000 33.58291  ? 236 VAL A CB  1 
ATOM   1569 C CG1 . VAL A 1 237 ? -52.14822 -138.12844 7.45890   1.000 35.42381  ? 236 VAL A CG1 1 
ATOM   1570 C CG2 . VAL A 1 237 ? -50.58687 -136.67539 8.78451   1.000 36.30212  ? 236 VAL A CG2 1 
ATOM   1571 N N   . CYS A 1 238 ? -52.60330 -135.20854 11.23153  1.000 35.40162  ? 237 CYS A N   1 
ATOM   1572 C CA  . CYS A 1 238 ? -52.38515 -134.80309 12.61423  1.000 38.34649  ? 237 CYS A CA  1 
ATOM   1573 C C   . CYS A 1 238 ? -53.55707 -134.04520 13.22137  1.000 36.50634  ? 237 CYS A C   1 
ATOM   1574 O O   . CYS A 1 238 ? -53.59551 -133.88056 14.44514  1.000 40.19053  ? 237 CYS A O   1 
ATOM   1575 C CB  . CYS A 1 238 ? -51.11754 -133.94500 12.72503  1.000 35.81084  ? 237 CYS A CB  1 
ATOM   1576 S SG  . CYS A 1 238 ? -49.59528 -134.86591 12.44910  1.000 41.09225  ? 237 CYS A SG  1 
ATOM   1577 N N   . GLY A 1 239 ? -54.51008 -133.58404 12.41066  1.000 34.07304  ? 238 GLY A N   1 
ATOM   1578 C CA  . GLY A 1 239 ? -55.66845 -132.87924 12.91264  1.000 36.18730  ? 238 GLY A CA  1 
ATOM   1579 C C   . GLY A 1 239 ? -55.54191 -131.37191 12.95409  1.000 36.22943  ? 238 GLY A C   1 
ATOM   1580 O O   . GLY A 1 239 ? -56.53046 -130.69516 13.26457  1.000 38.49819  ? 238 GLY A O   1 
ATOM   1581 N N   . ASP A 1 240 ? -54.36186 -130.82575 12.67059  1.000 33.69076  ? 239 ASP A N   1 
ATOM   1582 C CA  . ASP A 1 240 ? -54.18191 -129.38440 12.55180  1.000 36.60352  ? 239 ASP A CA  1 
ATOM   1583 C C   . ASP A 1 240 ? -52.86634 -129.12882 11.82763  1.000 38.57817  ? 239 ASP A C   1 
ATOM   1584 O O   . ASP A 1 240 ? -52.03331 -130.02640 11.67877  1.000 37.02271  ? 239 ASP A O   1 
ATOM   1585 C CB  . ASP A 1 240 ? -54.21030 -128.68942 13.91965  1.000 37.45738  ? 239 ASP A CB  1 
ATOM   1586 C CG  . ASP A 1 240 ? -54.56094 -127.21535 13.81250  1.000 42.80918  ? 239 ASP A CG  1 
ATOM   1587 O OD1 . ASP A 1 240 ? -54.88573 -126.76289 12.69199  1.000 42.48417  ? 239 ASP A OD1 1 
ATOM   1588 O OD2 . ASP A 1 240 ? -54.51499 -126.50940 14.84264  1.000 48.51185  ? 239 ASP A OD2 1 
ATOM   1589 N N   . ILE A 1 241 ? -52.69378 -127.89184 11.36898  1.000 37.68579  ? 240 ILE A N   1 
ATOM   1590 C CA  . ILE A 1 241 ? -51.51975 -127.50898 10.58593  1.000 36.77784  ? 240 ILE A CA  1 
ATOM   1591 C C   . ILE A 1 241 ? -50.29387 -127.50361 11.49388  1.000 36.62560  ? 240 ILE A C   1 
ATOM   1592 O O   . ILE A 1 241 ? -50.43232 -127.34483 12.71447  1.000 37.87908  ? 240 ILE A O   1 
ATOM   1593 C CB  . ILE A 1 241 ? -51.72313 -126.14445 9.90536   1.000 38.70018  ? 240 ILE A CB  1 
ATOM   1594 C CG1 . ILE A 1 241 ? -51.96036 -125.04982 10.94624  1.000 39.39402  ? 240 ILE A CG1 1 
ATOM   1595 C CG2 . ILE A 1 241 ? -52.88072 -126.20601 8.91315   1.000 33.22061  ? 240 ILE A CG2 1 
ATOM   1596 C CD1 . ILE A 1 241 ? -52.11844 -123.67333 10.33692  1.000 39.61785  ? 240 ILE A CD1 1 
ATOM   1597 N N   . PRO A 1 242 ? -49.07991 -127.68549 10.95763  1.000 37.15685  ? 241 PRO A N   1 
ATOM   1598 C CA  . PRO A 1 242 ? -47.90240 -127.76619 11.83238  1.000 38.23374  ? 241 PRO A CA  1 
ATOM   1599 C C   . PRO A 1 242 ? -47.41961 -126.41246 12.32754  1.000 41.97323  ? 241 PRO A C   1 
ATOM   1600 O O   . PRO A 1 242 ? -46.93646 -126.30430 13.45826  1.000 41.54973  ? 241 PRO A O   1 
ATOM   1601 C CB  . PRO A 1 242 ? -46.85182 -128.43680 10.93909  1.000 35.49566  ? 241 PRO A CB  1 
ATOM   1602 C CG  . PRO A 1 242 ? -47.23420 -128.01736 9.55707   1.000 37.73692  ? 241 PRO A CG  1 
ATOM   1603 C CD  . PRO A 1 242 ? -48.73889 -127.94811 9.54608   1.000 36.32181  ? 241 PRO A CD  1 
ATOM   1604 N N   . PHE A 1 243 ? -47.54329 -125.37521 11.50167  1.000 40.78496  ? 242 PHE A N   1 
ATOM   1605 C CA  . PHE A 1 243 ? -46.93923 -124.07915 11.77698  1.000 40.48205  ? 242 PHE A CA  1 
ATOM   1606 C C   . PHE A 1 243 ? -48.01391 -123.01490 11.94852  1.000 43.53719  ? 242 PHE A C   1 
ATOM   1607 O O   . PHE A 1 243 ? -48.97199 -122.95310 11.17096  1.000 39.52710  ? 242 PHE A O   1 
ATOM   1608 C CB  . PHE A 1 243 ? -45.98698 -123.66281 10.64904  1.000 39.35880  ? 242 PHE A CB  1 
ATOM   1609 C CG  . PHE A 1 243 ? -44.97171 -124.71148 10.28509  1.000 41.31431  ? 242 PHE A CG  1 
ATOM   1610 C CD1 . PHE A 1 243 ? -44.29719 -125.41958 11.26797  1.000 43.92688  ? 242 PHE A CD1 1 
ATOM   1611 C CD2 . PHE A 1 243 ? -44.69360 -124.98871 8.95422   1.000 39.74532  ? 242 PHE A CD2 1 
ATOM   1612 C CE1 . PHE A 1 243 ? -43.36123 -126.38149 10.93239  1.000 42.52124  ? 242 PHE A CE1 1 
ATOM   1613 C CE2 . PHE A 1 243 ? -43.75942 -125.94989 8.61078   1.000 38.80485  ? 242 PHE A CE2 1 
ATOM   1614 C CZ  . PHE A 1 243 ? -43.09290 -126.64902 9.60187   1.000 42.17956  ? 242 PHE A CZ  1 
ATOM   1615 N N   . GLU A 1 244 ? -47.84378 -122.17361 12.97115  1.000 42.09077  ? 243 GLU A N   1 
ATOM   1616 C CA  . GLU A 1 244 ? -48.68824 -121.00597 13.17524  1.000 45.43063  ? 243 GLU A CA  1 
ATOM   1617 C C   . GLU A 1 244 ? -47.93862 -119.68589 13.08276  1.000 50.34256  ? 243 GLU A C   1 
ATOM   1618 O O   . GLU A 1 244 ? -48.57704 -118.65360 12.84895  1.000 51.90445  ? 243 GLU A O   1 
ATOM   1619 C CB  . GLU A 1 244 ? -49.38756 -121.06952 14.54531  1.000 49.65777  ? 243 GLU A CB  1 
ATOM   1620 C CG  . GLU A 1 244 ? -50.47220 -122.13545 14.66724  1.000 52.62082  ? 243 GLU A CG  1 
ATOM   1621 C CD  . GLU A 1 244 ? -51.77052 -121.75126 13.97352  1.000 50.94454  ? 243 GLU A CD  1 
ATOM   1622 O OE1 . GLU A 1 244 ? -51.88768 -120.60234 13.49570  1.000 49.91388  ? 243 GLU A OE1 1 
ATOM   1623 O OE2 . GLU A 1 244 ? -52.67936 -122.60467 13.90836  1.000 49.80897  ? 243 GLU A OE2 1 
ATOM   1624 N N   . HIS A 1 245 ? -46.61786 -119.68550 13.25166  1.000 49.10709  ? 244 HIS A N   1 
ATOM   1625 C CA  . HIS A 1 245 ? -45.82498 -118.46678 13.30264  1.000 51.53343  ? 244 HIS A CA  1 
ATOM   1626 C C   . HIS A 1 245 ? -44.72938 -118.50628 12.24661  1.000 51.50204  ? 244 HIS A C   1 
ATOM   1627 O O   . HIS A 1 245 ? -44.30765 -119.57688 11.79992  1.000 49.12767  ? 244 HIS A O   1 
ATOM   1628 C CB  . HIS A 1 245 ? -45.20116 -118.27189 14.68973  1.000 58.48234  ? 244 HIS A CB  1 
ATOM   1629 C CG  . HIS A 1 245 ? -46.17650 -118.42468 15.81328  1.000 57.79769  ? 244 HIS A CG  1 
ATOM   1630 N ND1 . HIS A 1 245 ? -46.95904 -117.38473 16.26578  1.000 59.01881  ? 244 HIS A ND1 1 
ATOM   1631 C CD2 . HIS A 1 245 ? -46.50514 -119.49966 16.56817  1.000 61.10701  ? 244 HIS A CD2 1 
ATOM   1632 C CE1 . HIS A 1 245 ? -47.72291 -117.81049 17.25601  1.000 63.62651  ? 244 HIS A CE1 1 
ATOM   1633 N NE2 . HIS A 1 245 ? -47.46693 -119.09043 17.45927  1.000 66.62073  ? 244 HIS A NE2 1 
ATOM   1634 N N   . ASP A 1 246 ? -44.26439 -117.31221 11.86310  1.000 51.08625  ? 245 ASP A N   1 
ATOM   1635 C CA  . ASP A 1 246 ? -43.25102 -117.20263 10.81657  1.000 54.63839  ? 245 ASP A CA  1 
ATOM   1636 C C   . ASP A 1 246 ? -41.99472 -117.98686 11.16844  1.000 52.51702  ? 245 ASP A C   1 
ATOM   1637 O O   . ASP A 1 246 ? -41.39342 -118.63004 10.30098  1.000 51.51832  ? 245 ASP A O   1 
ATOM   1638 C CB  . ASP A 1 246 ? -42.90425 -115.73452 10.57193  1.000 53.22395  ? 245 ASP A CB  1 
ATOM   1639 C CG  . ASP A 1 246 ? -44.01216 -114.98499 9.86555   1.000 56.34998  ? 245 ASP A CG  1 
ATOM   1640 O OD1 . ASP A 1 246 ? -45.01636 -115.62313 9.48443   1.000 50.99357  ? 245 ASP A OD1 1 
ATOM   1641 O OD2 . ASP A 1 246 ? -43.87456 -113.75751 9.68739   1.000 57.07054  ? 245 ASP A OD2 1 
ATOM   1642 N N   . GLU A 1 247 ? -41.58583 -117.94808 12.43846  1.000 53.51182  ? 246 GLU A N   1 
ATOM   1643 C CA  . GLU A 1 247 ? -40.36028 -118.62445 12.84840  1.000 51.86086  ? 246 GLU A CA  1 
ATOM   1644 C C   . GLU A 1 247 ? -40.47034 -120.13194 12.67615  1.000 49.88402  ? 246 GLU A C   1 
ATOM   1645 O O   . GLU A 1 247 ? -39.46793 -120.79762 12.39301  1.000 49.19084  ? 246 GLU A O   1 
ATOM   1646 C CB  . GLU A 1 247 ? -40.02714 -118.27737 14.30333  1.000 59.73508  ? 246 GLU A CB  1 
ATOM   1647 C CG  . GLU A 1 247 ? -40.26622 -116.81765 14.66864  1.000 64.22838  ? 246 GLU A CG  1 
ATOM   1648 C CD  . GLU A 1 247 ? -41.70513 -116.54418 15.07934  1.000 73.28456  ? 246 GLU A CD  1 
ATOM   1649 O OE1 . GLU A 1 247 ? -42.20054 -117.22310 16.00580  1.000 79.37734  ? 246 GLU A OE1 1 
ATOM   1650 O OE2 . GLU A 1 247 ? -42.34350 -115.66107 14.46589  1.000 71.27291  ? 246 GLU A OE2 1 
ATOM   1651 N N   . GLU A 1 248 ? -41.67474 -120.68590 12.84024  1.000 51.12058  ? 247 GLU A N   1 
ATOM   1652 C CA  . GLU A 1 248 ? -41.87202 -122.11429 12.61545  1.000 47.44610  ? 247 GLU A CA  1 
ATOM   1653 C C   . GLU A 1 248 ? -41.81178 -122.45360 11.13142  1.000 48.20359  ? 247 GLU A C   1 
ATOM   1654 O O   . GLU A 1 248 ? -41.28674 -123.50718 10.75157  1.000 48.93514  ? 247 GLU A O   1 
ATOM   1655 C CB  . GLU A 1 248 ? -43.20640 -122.55893 13.21647  1.000 48.95872  ? 247 GLU A CB  1 
ATOM   1656 C CG  . GLU A 1 248 ? -43.27029 -122.44071 14.73505  1.000 47.98311  ? 247 GLU A CG  1 
ATOM   1657 C CD  . GLU A 1 248 ? -44.67033 -122.64417 15.28675  1.000 50.29867  ? 247 GLU A CD  1 
ATOM   1658 O OE1 . GLU A 1 248 ? -45.64786 -122.31394 14.58518  1.000 48.25307  ? 247 GLU A OE1 1 
ATOM   1659 O OE2 . GLU A 1 248 ? -44.79378 -123.13284 16.42834  1.000 60.96725  ? 247 GLU A OE2 1 
ATOM   1660 N N   . ILE A 1 249 ? -42.34049 -121.57418 10.27685  1.000 48.47826  ? 248 ILE A N   1 
ATOM   1661 C CA  . ILE A 1 249 ? -42.33520 -121.83930 8.83896   1.000 45.19191  ? 248 ILE A CA  1 
ATOM   1662 C C   . ILE A 1 249 ? -40.90546 -121.93728 8.32309   1.000 47.01505  ? 248 ILE A C   1 
ATOM   1663 O O   . ILE A 1 249 ? -40.55136 -122.86942 7.59198   1.000 44.94442  ? 248 ILE A O   1 
ATOM   1664 C CB  . ILE A 1 249 ? -43.13366 -120.75884 8.08681   1.000 45.29639  ? 248 ILE A CB  1 
ATOM   1665 C CG1 . ILE A 1 249 ? -44.59377 -120.76172 8.54327   1.000 42.06279  ? 248 ILE A CG1 1 
ATOM   1666 C CG2 . ILE A 1 249 ? -43.04218 -120.97722 6.57772   1.000 42.59340  ? 248 ILE A CG2 1 
ATOM   1667 C CD1 . ILE A 1 249 ? -45.42370 -119.66254 7.93042   1.000 45.56257  ? 248 ILE A CD1 1 
ATOM   1668 N N   . ILE A 1 250 ? -40.05707 -120.97888 8.70321   1.000 45.65575  ? 249 ILE A N   1 
ATOM   1669 C CA  . ILE A 1 250 ? -38.67611 -120.98436 8.22659   1.000 51.46425  ? 249 ILE A CA  1 
ATOM   1670 C C   . ILE A 1 250 ? -37.76504 -121.86142 9.06718   1.000 54.12703  ? 249 ILE A C   1 
ATOM   1671 O O   . ILE A 1 250 ? -36.60708 -122.07119 8.68560   1.000 54.39753  ? 249 ILE A O   1 
ATOM   1672 C CB  . ILE A 1 250 ? -38.10507 -119.55456 8.18613   1.000 52.77042  ? 249 ILE A CB  1 
ATOM   1673 C CG1 . ILE A 1 250 ? -37.87873 -119.02869 9.60426   1.000 51.50043  ? 249 ILE A CG1 1 
ATOM   1674 C CG2 . ILE A 1 250 ? -39.04453 -118.63107 7.42603   1.000 51.72793  ? 249 ILE A CG2 1 
ATOM   1675 C CD1 . ILE A 1 250 ? -37.31976 -117.62683 9.65037   1.000 57.32194  ? 249 ILE A CD1 1 
ATOM   1676 N N   . GLY A 1 251 ? -38.25644 -122.38835 10.19194  1.000 49.48272  ? 250 GLY A N   1 
ATOM   1677 C CA  . GLY A 1 251 ? -37.38932 -123.12889 11.09608  1.000 52.14344  ? 250 GLY A CA  1 
ATOM   1678 C C   . GLY A 1 251 ? -36.86502 -124.42528 10.50477  1.000 55.87064  ? 250 GLY A C   1 
ATOM   1679 O O   . GLY A 1 251 ? -35.70038 -124.78143 10.70490  1.000 60.69053  ? 250 GLY A O   1 
ATOM   1680 N N   . GLY A 1 252 ? -37.71010 -125.15140 9.78017   1.000 51.49200  ? 251 GLY A N   1 
ATOM   1681 C CA  . GLY A 1 252 ? -37.29660 -126.40419 9.17923   1.000 57.42398  ? 251 GLY A CA  1 
ATOM   1682 C C   . GLY A 1 252 ? -37.40911 -127.62403 10.06464  1.000 64.29520  ? 251 GLY A C   1 
ATOM   1683 O O   . GLY A 1 252 ? -36.72957 -128.62371 9.80145   1.000 59.89213  ? 251 GLY A O   1 
ATOM   1684 N N   . GLN A 1 253 ? -38.23660 -127.57939 11.10733  1.000 54.06468  ? 252 GLN A N   1 
ATOM   1685 C CA  . GLN A 1 253 ? -38.45453 -128.71703 11.98927  1.000 47.76060  ? 252 GLN A CA  1 
ATOM   1686 C C   . GLN A 1 253 ? -39.93491 -129.06547 11.99605  1.000 50.00673  ? 252 GLN A C   1 
ATOM   1687 O O   . GLN A 1 253 ? -40.78021 -128.20136 12.25142  1.000 51.09506  ? 252 GLN A O   1 
ATOM   1688 C CB  . GLN A 1 253 ? -37.96899 -128.41964 13.41077  1.000 52.16706  ? 252 GLN A CB  1 
ATOM   1689 N N   . VAL A 1 254 ? -40.24361 -130.32678 11.71766  1.000 44.33431  ? 253 VAL A N   1 
ATOM   1690 C CA  . VAL A 1 254 ? -41.61445 -130.81954 11.69276  1.000 41.42343  ? 253 VAL A CA  1 
ATOM   1691 C C   . VAL A 1 254 ? -41.76639 -131.81702 12.83461  1.000 45.66796  ? 253 VAL A C   1 
ATOM   1692 O O   . VAL A 1 254 ? -41.22349 -132.92749 12.78048  1.000 42.91012  ? 253 VAL A O   1 
ATOM   1693 C CB  . VAL A 1 254 ? -41.96837 -131.45450 10.34095  1.000 43.87138  ? 253 VAL A CB  1 
ATOM   1694 C CG1 . VAL A 1 254 ? -43.42159 -131.91352 10.33069  1.000 41.16769  ? 253 VAL A CG1 1 
ATOM   1695 C CG2 . VAL A 1 254 ? -41.71139 -130.46434 9.20901   1.000 44.12245  ? 253 VAL A CG2 1 
ATOM   1696 N N   . PHE A 1 255 ? -42.49269 -131.41603 13.87562  1.000 39.18656  ? 254 PHE A N   1 
ATOM   1697 C CA  . PHE A 1 255 ? -42.82999 -132.29694 14.98610  1.000 40.26421  ? 254 PHE A CA  1 
ATOM   1698 C C   . PHE A 1 255 ? -44.19190 -132.92059 14.71949  1.000 42.39263  ? 254 PHE A C   1 
ATOM   1699 O O   . PHE A 1 255 ? -45.14159 -132.21759 14.36066  1.000 37.35356  ? 254 PHE A O   1 
ATOM   1700 C CB  . PHE A 1 255 ? -42.84581 -131.52234 16.30739  1.000 40.48226  ? 254 PHE A CB  1 
ATOM   1701 C CG  . PHE A 1 255 ? -43.37219 -132.31446 17.48169  1.000 46.81442  ? 254 PHE A CG  1 
ATOM   1702 C CD1 . PHE A 1 255 ? -42.53177 -133.14509 18.20852  1.000 43.94869  ? 254 PHE A CD1 1 
ATOM   1703 C CD2 . PHE A 1 255 ? -44.70280 -132.21319 17.86921  1.000 44.43663  ? 254 PHE A CD2 1 
ATOM   1704 C CE1 . PHE A 1 255 ? -43.00781 -133.86758 19.29197  1.000 42.94153  ? 254 PHE A CE1 1 
ATOM   1705 C CE2 . PHE A 1 255 ? -45.18585 -132.93518 18.95033  1.000 45.30420  ? 254 PHE A CE2 1 
ATOM   1706 C CZ  . PHE A 1 255 ? -44.33615 -133.76033 19.66368  1.000 43.96584  ? 254 PHE A CZ  1 
ATOM   1707 N N   . PHE A 1 256 ? -44.28743 -134.23425 14.89082  1.000 39.42442  ? 255 PHE A N   1 
ATOM   1708 C CA  . PHE A 1 256 ? -45.53098 -134.95750 14.65263  1.000 43.17804  ? 255 PHE A CA  1 
ATOM   1709 C C   . PHE A 1 256 ? -46.24521 -135.17135 15.98222  1.000 39.66895  ? 255 PHE A C   1 
ATOM   1710 O O   . PHE A 1 256 ? -45.74966 -135.88846 16.85724  1.000 45.43349  ? 255 PHE A O   1 
ATOM   1711 C CB  . PHE A 1 256 ? -45.26035 -136.27112 13.92591  1.000 39.66362  ? 255 PHE A CB  1 
ATOM   1712 C CG  . PHE A 1 256 ? -45.11452 -136.10240 12.44422  1.000 38.83850  ? 255 PHE A CG  1 
ATOM   1713 C CD1 . PHE A 1 256 ? -46.22459 -136.14603 11.62146  1.000 41.01248  ? 255 PHE A CD1 1 
ATOM   1714 C CD2 . PHE A 1 256 ? -43.87567 -135.86321 11.87739  1.000 41.76238  ? 255 PHE A CD2 1 
ATOM   1715 C CE1 . PHE A 1 256 ? -46.10010 -135.97329 10.25275  1.000 40.64588  ? 255 PHE A CE1 1 
ATOM   1716 C CE2 . PHE A 1 256 ? -43.74341 -135.68958 10.50982  1.000 43.37386  ? 255 PHE A CE2 1 
ATOM   1717 C CZ  . PHE A 1 256 ? -44.85701 -135.74571 9.69924   1.000 40.10418  ? 255 PHE A CZ  1 
ATOM   1718 N N   . ARG A 1 257 ? -47.40267 -134.52456 16.13081  1.000 42.69458  ? 256 ARG A N   1 
ATOM   1719 C CA  . ARG A 1 257 ? -48.20202 -134.58272 17.34666  1.000 46.71494  ? 256 ARG A CA  1 
ATOM   1720 C C   . ARG A 1 257 ? -49.11300 -135.79938 17.39235  1.000 42.97177  ? 256 ARG A C   1 
ATOM   1721 O O   . ARG A 1 257 ? -49.76426 -136.03199 18.41459  1.000 44.81594  ? 256 ARG A O   1 
ATOM   1722 C CB  . ARG A 1 257 ? -49.04197 -133.30768 17.47518  1.000 48.31986  ? 256 ARG A CB  1 
ATOM   1723 C CG  . ARG A 1 257 ? -50.07113 -133.12262 16.35432  1.000 46.20663  ? 256 ARG A CG  1 
ATOM   1724 C CD  . ARG A 1 257 ? -50.63100 -131.70359 16.33365  1.000 48.02524  ? 256 ARG A CD  1 
ATOM   1725 N NE  . ARG A 1 257 ? -49.66235 -130.74336 15.81442  1.000 50.24079  ? 256 ARG A NE  1 
ATOM   1726 C CZ  . ARG A 1 257 ? -49.78472 -129.42527 15.90530  1.000 47.42988  ? 256 ARG A CZ  1 
ATOM   1727 N NH1 . ARG A 1 257 ? -50.82641 -128.86570 16.49899  1.000 50.26769  ? 256 ARG A NH1 1 
ATOM   1728 N NH2 . ARG A 1 257 ? -48.83311 -128.64891 15.39513  1.000 44.78356  ? 256 ARG A NH2 1 
ATOM   1729 N N   . GLN A 1 258 ? -49.18202 -136.56812 16.31335  1.000 41.49336  ? 257 GLN A N   1 
ATOM   1730 C CA  . GLN A 1 258 ? -49.98681 -137.77427 16.26138  1.000 42.65717  ? 257 GLN A CA  1 
ATOM   1731 C C   . GLN A 1 258 ? -49.13691 -138.90902 15.71693  1.000 40.36733  ? 257 GLN A C   1 
ATOM   1732 O O   . GLN A 1 258 ? -48.09699 -138.68774 15.08962  1.000 38.98446  ? 257 GLN A O   1 
ATOM   1733 C CB  . GLN A 1 258 ? -51.23764 -137.58128 15.39066  1.000 42.19025  ? 257 GLN A CB  1 
ATOM   1734 C CG  . GLN A 1 258 ? -52.36178 -136.84099 16.09248  1.000 54.90907  ? 257 GLN A CG  1 
ATOM   1735 C CD  . GLN A 1 258 ? -53.20444 -137.75972 16.95180  1.000 53.04696  ? 257 GLN A CD  1 
ATOM   1736 O OE1 . GLN A 1 258 ? -53.72475 -138.77059 16.47294  1.000 52.18341  ? 257 GLN A OE1 1 
ATOM   1737 N NE2 . GLN A 1 258 ? -53.33709 -137.42069 18.23008  1.000 64.26468  ? 257 GLN A NE2 1 
ATOM   1738 N N   . ARG A 1 259 ? -49.58967 -140.13416 15.97358  1.000 37.27780  ? 258 ARG A N   1 
ATOM   1739 C CA  . ARG A 1 259 ? -48.96332 -141.29958 15.37013  1.000 38.27254  ? 258 ARG A CA  1 
ATOM   1740 C C   . ARG A 1 259 ? -49.13813 -141.24221 13.85554  1.000 37.82297  ? 258 ARG A C   1 
ATOM   1741 O O   . ARG A 1 259 ? -50.26593 -141.28861 13.35530  1.000 36.49936  ? 258 ARG A O   1 
ATOM   1742 C CB  . ARG A 1 259 ? -49.55748 -142.58777 15.94039  1.000 38.78733  ? 258 ARG A CB  1 
ATOM   1743 C CG  . ARG A 1 259 ? -49.23400 -143.82269 15.10943  1.000 44.41272  ? 258 ARG A CG  1 
ATOM   1744 C CD  . ARG A 1 259 ? -47.74817 -144.11379 15.11862  1.000 41.58201  ? 258 ARG A CD  1 
ATOM   1745 N NE  . ARG A 1 259 ? -47.35250 -145.00078 14.03042  1.000 41.27159  ? 258 ARG A NE  1 
ATOM   1746 C CZ  . ARG A 1 259 ? -46.20802 -145.67076 13.99535  1.000 46.28684  ? 258 ARG A CZ  1 
ATOM   1747 N NH1 . ARG A 1 259 ? -45.33391 -145.60104 14.98968  1.000 42.36635  ? 258 ARG A NH1 1 
ATOM   1748 N NH2 . ARG A 1 259 ? -45.93795 -146.44051 12.94330  1.000 42.49781  ? 258 ARG A NH2 1 
ATOM   1749 N N   . VAL A 1 260 ? -48.03119 -141.11740 13.12417  1.000 36.24550  ? 259 VAL A N   1 
ATOM   1750 C CA  . VAL A 1 260 ? -48.03102 -141.05398 11.66658  1.000 39.89237  ? 259 VAL A CA  1 
ATOM   1751 C C   . VAL A 1 260 ? -46.97746 -142.02504 11.15454  1.000 40.85664  ? 259 VAL A C   1 
ATOM   1752 O O   . VAL A 1 260 ? -45.84538 -142.03094 11.65103  1.000 41.60001  ? 259 VAL A O   1 
ATOM   1753 C CB  . VAL A 1 260 ? -47.74145 -139.62902 11.15235  1.000 36.12729  ? 259 VAL A CB  1 
ATOM   1754 C CG1 . VAL A 1 260 ? -47.64228 -139.62128 9.63896   1.000 38.86113  ? 259 VAL A CG1 1 
ATOM   1755 C CG2 . VAL A 1 260 ? -48.80969 -138.65034 11.62266  1.000 33.70779  ? 259 VAL A CG2 1 
ATOM   1756 N N   . SER A 1 261 ? -47.34384 -142.83832 10.16506  1.000 40.30094  ? 260 SER A N   1 
ATOM   1757 C CA  . SER A 1 261 ? -46.42528 -143.83292 9.61219   1.000 42.56803  ? 260 SER A CA  1 
ATOM   1758 C C   . SER A 1 261 ? -45.14793 -143.17492 9.09858   1.000 38.47452  ? 260 SER A C   1 
ATOM   1759 O O   . SER A 1 261 ? -45.15757 -142.00829 8.70277   1.000 39.87450  ? 260 SER A O   1 
ATOM   1760 C CB  . SER A 1 261 ? -47.09353 -144.62816 8.48543   1.000 41.83510  ? 260 SER A CB  1 
ATOM   1761 O OG  . SER A 1 261 ? -47.32162 -143.81511 7.34642   1.000 38.77076  ? 260 SER A OG  1 
HETATM 1762 N N   . SEP A 1 262 ? -44.05128 -143.92562 9.12467   1.000 38.89128  ? 261 SEP A N   1 
HETATM 1763 C CA  . SEP A 1 262 ? -42.76129 -143.42515 8.66065   1.000 42.56634  ? 261 SEP A CA  1 
HETATM 1764 C CB  . SEP A 1 262 ? -41.67702 -144.48885 8.86331   1.000 43.11835  ? 261 SEP A CB  1 
HETATM 1765 O OG  . SEP A 1 262 ? -41.46716 -144.73267 10.24788  1.000 51.20629  ? 261 SEP A OG  1 
HETATM 1766 C C   . SEP A 1 262 ? -42.81791 -142.99365 7.19196   1.000 43.94750  ? 261 SEP A C   1 
HETATM 1767 O O   . SEP A 1 262 ? -42.20059 -142.00049 6.80124   1.000 39.85873  ? 261 SEP A O   1 
HETATM 1768 P P   . SEP A 1 262 ? -41.95010 -146.21412 10.67921  0.706 53.87140  ? 261 SEP A P   1 
HETATM 1769 O O1P . SEP A 1 262 ? -41.10511 -147.32879 9.88575   0.706 49.35025  ? 261 SEP A O1P 1 
HETATM 1770 O O2P . SEP A 1 262 ? -41.72224 -146.40914 12.26773  0.706 46.85772  ? 261 SEP A O2P 1 
HETATM 1771 O O3P . SEP A 1 262 ? -43.51226 -146.39509 10.31515  0.706 47.78797  ? 261 SEP A O3P 1 
ATOM   1772 N N   . GLU A 1 263 ? -43.56875 -143.73394 6.38365   1.000 41.73734  ? 262 GLU A N   1 
ATOM   1773 C CA  . GLU A 1 263 ? -43.71090 -143.40548 4.96574   1.000 43.57824  ? 262 GLU A CA  1 
ATOM   1774 C C   . GLU A 1 263 ? -44.41334 -142.05880 4.78484   1.000 41.20781  ? 262 GLU A C   1 
ATOM   1775 O O   . GLU A 1 263 ? -43.97488 -141.22261 3.99482   1.000 38.57929  ? 262 GLU A O   1 
ATOM   1776 C CB  . GLU A 1 263 ? -44.47390 -144.51074 4.22828   1.000 43.83622  ? 262 GLU A CB  1 
ATOM   1777 C CG  . GLU A 1 263 ? -43.70532 -145.82642 4.08836   1.000 50.63112  ? 262 GLU A CG  1 
ATOM   1778 C CD  . GLU A 1 263 ? -43.60140 -146.60717 5.39277   1.000 58.30506  ? 262 GLU A CD  1 
ATOM   1779 O OE1 . GLU A 1 263 ? -44.30142 -146.25391 6.37204   1.000 51.99744  ? 262 GLU A OE1 1 
ATOM   1780 O OE2 . GLU A 1 263 ? -42.81093 -147.57703 5.44269   1.000 66.80809  ? 262 GLU A OE2 1 
ATOM   1781 N N   . CYS A 1 264 ? -45.49774 -141.84687 5.53545   1.000 39.37682  ? 263 CYS A N   1 
ATOM   1782 C CA  . CYS A 1 264 ? -46.21625 -140.57955 5.44352   1.000 38.17250  ? 263 CYS A CA  1 
ATOM   1783 C C   . CYS A 1 264 ? -45.37536 -139.42414 5.97718   1.000 39.38057  ? 263 CYS A C   1 
ATOM   1784 O O   . CYS A 1 264 ? -45.36800 -138.33444 5.38979   1.000 36.32257  ? 263 CYS A O   1 
ATOM   1785 C CB  . CYS A 1 264 ? -47.54466 -140.67398 6.19335   1.000 36.58831  ? 263 CYS A CB  1 
ATOM   1786 S SG  . CYS A 1 264 ? -48.58844 -139.20154 6.05950   1.000 37.39065  ? 263 CYS A SG  1 
ATOM   1787 N N   . GLN A 1 265 ? -44.66457 -139.64367 7.09055   1.000 37.50271  ? 264 GLN A N   1 
ATOM   1788 C CA  . GLN A 1 265 ? -43.78414 -138.61183 7.63461   1.000 40.71162  ? 264 GLN A CA  1 
ATOM   1789 C C   . GLN A 1 265 ? -42.73018 -138.19250 6.61730   1.000 39.63838  ? 264 GLN A C   1 
ATOM   1790 O O   . GLN A 1 265 ? -42.42238 -137.00159 6.48397   1.000 37.34214  ? 264 GLN A O   1 
ATOM   1791 C CB  . GLN A 1 265 ? -43.09807 -139.10702 8.91401   1.000 39.96015  ? 264 GLN A CB  1 
ATOM   1792 C CG  . GLN A 1 265 ? -43.96236 -139.17152 10.17909  1.000 38.46522  ? 264 GLN A CG  1 
ATOM   1793 C CD  . GLN A 1 265 ? -43.11231 -139.22705 11.44373  1.000 42.17081  ? 264 GLN A CD  1 
ATOM   1794 O OE1 . GLN A 1 265 ? -41.90925 -138.98022 11.39653  1.000 44.25340  ? 264 GLN A OE1 1 
ATOM   1795 N NE2 . GLN A 1 265 ? -43.73400 -139.54296 12.57668  1.000 39.46745  ? 264 GLN A NE2 1 
ATOM   1796 N N   . HIS A 1 266 ? -42.15462 -139.16170 5.90223   1.000 36.97438  ? 265 HIS A N   1 
ATOM   1797 C CA  . HIS A 1 266 ? -41.12768 -138.84892 4.91416   1.000 41.37758  ? 265 HIS A CA  1 
ATOM   1798 C C   . HIS A 1 266 ? -41.68983 -137.98651 3.78857   1.000 40.02038  ? 265 HIS A C   1 
ATOM   1799 O O   . HIS A 1 266 ? -41.07379 -136.99203 3.38817   1.000 39.15838  ? 265 HIS A O   1 
ATOM   1800 C CB  . HIS A 1 266 ? -40.52452 -140.13998 4.35775   1.000 43.53514  ? 265 HIS A CB  1 
ATOM   1801 C CG  . HIS A 1 266 ? -39.52930 -139.91699 3.26126   1.000 45.88524  ? 265 HIS A CG  1 
ATOM   1802 N ND1 . HIS A 1 266 ? -39.89343 -139.81261 1.93651   1.000 45.04919  ? 265 HIS A ND1 1 
ATOM   1803 C CD2 . HIS A 1 266 ? -38.18266 -139.77645 3.29302   1.000 47.48659  ? 265 HIS A CD2 1 
ATOM   1804 C CE1 . HIS A 1 266 ? -38.81458 -139.61975 1.19857   1.000 44.68010  ? 265 HIS A CE1 1 
ATOM   1805 N NE2 . HIS A 1 266 ? -37.76346 -139.59205 1.99754   1.000 45.99265  ? 265 HIS A NE2 1 
ATOM   1806 N N   . LEU A 1 267 ? -42.86265 -138.35260 3.26254   1.000 37.79685  ? 266 LEU A N   1 
ATOM   1807 C CA  . LEU A 1 267 ? -43.46499 -137.55715 2.19523   1.000 38.77701  ? 266 LEU A CA  1 
ATOM   1808 C C   . LEU A 1 267 ? -43.73798 -136.13318 2.66199   1.000 38.47589  ? 266 LEU A C   1 
ATOM   1809 O O   . LEU A 1 267 ? -43.44284 -135.16895 1.94534   1.000 35.74791  ? 266 LEU A O   1 
ATOM   1810 C CB  . LEU A 1 267 ? -44.75351 -138.21776 1.70323   1.000 33.80395  ? 266 LEU A CB  1 
ATOM   1811 C CG  . LEU A 1 267 ? -45.52620 -137.45712 0.61860   1.000 40.14875  ? 266 LEU A CG  1 
ATOM   1812 C CD1 . LEU A 1 267 ? -44.67202 -137.24844 -0.63379  1.000 33.58359  ? 266 LEU A CD1 1 
ATOM   1813 C CD2 . LEU A 1 267 ? -46.83216 -138.16951 0.26724   1.000 35.52946  ? 266 LEU A CD2 1 
ATOM   1814 N N   . ILE A 1 268 ? -44.28346 -135.98642 3.87279   1.000 37.61164  ? 267 ILE A N   1 
ATOM   1815 C CA  . ILE A 1 268 ? -44.56323 -134.66485 4.42851   1.000 35.48332  ? 267 ILE A CA  1 
ATOM   1816 C C   . ILE A 1 268 ? -43.28241 -133.84731 4.53777   1.000 34.82502  ? 267 ILE A C   1 
ATOM   1817 O O   . ILE A 1 268 ? -43.22387 -132.69135 4.10279   1.000 35.66376  ? 267 ILE A O   1 
ATOM   1818 C CB  . ILE A 1 268 ? -45.25776 -134.79862 5.79582   1.000 38.86644  ? 267 ILE A CB  1 
ATOM   1819 C CG1 . ILE A 1 268 ? -46.65685 -135.39543 5.63474   1.000 36.89785  ? 267 ILE A CG1 1 
ATOM   1820 C CG2 . ILE A 1 268 ? -45.31048 -133.45084 6.50927   1.000 36.41358  ? 267 ILE A CG2 1 
ATOM   1821 C CD1 . ILE A 1 268 ? -47.33532 -135.72780 6.96223   1.000 33.17964  ? 267 ILE A CD1 1 
ATOM   1822 N N   . ARG A 1 269 ? -42.23967 -134.42888 5.13638   1.000 36.19681  ? 268 ARG A N   1 
ATOM   1823 C CA  . ARG A 1 269 ? -40.99003 -133.69204 5.29933   1.000 35.59494  ? 268 ARG A CA  1 
ATOM   1824 C C   . ARG A 1 269 ? -40.36322 -133.35898 3.95285   1.000 40.23938  ? 268 ARG A C   1 
ATOM   1825 O O   . ARG A 1 269 ? -39.74107 -132.30189 3.79920   1.000 38.87392  ? 268 ARG A O   1 
ATOM   1826 C CB  . ARG A 1 269 ? -40.01266 -134.48831 6.16844   1.000 39.67992  ? 268 ARG A CB  1 
ATOM   1827 C CG  . ARG A 1 269 ? -40.40101 -134.53660 7.64448   1.000 39.76242  ? 268 ARG A CG  1 
ATOM   1828 C CD  . ARG A 1 269 ? -39.25910 -135.05586 8.51474   1.000 45.34694  ? 268 ARG A CD  1 
ATOM   1829 N NE  . ARG A 1 269 ? -39.52768 -134.85930 9.93652   1.000 53.14412  ? 268 ARG A NE  1 
ATOM   1830 C CZ  . ARG A 1 269 ? -40.03581 -135.78451 10.74040  1.000 48.81901  ? 268 ARG A CZ  1 
ATOM   1831 N NH1 . ARG A 1 269 ? -40.30816 -137.00564 10.30612  1.000 49.90036  ? 268 ARG A NH1 1 
ATOM   1832 N NH2 . ARG A 1 269 ? -40.28065 -135.47666 12.01105  1.000 48.20307  ? 268 ARG A NH2 1 
ATOM   1833 N N   . TRP A 1 270 ? -40.52846 -134.23822 2.96623   1.000 36.47435  ? 269 TRP A N   1 
ATOM   1834 C CA  . TRP A 1 270 ? -40.05050 -133.94412 1.62047   1.000 40.20127  ? 269 TRP A CA  1 
ATOM   1835 C C   . TRP A 1 270 ? -40.76471 -132.72612 1.04312   1.000 39.14507  ? 269 TRP A C   1 
ATOM   1836 O O   . TRP A 1 270 ? -40.12484 -131.80960 0.51348   1.000 40.03013  ? 269 TRP A O   1 
ATOM   1837 C CB  . TRP A 1 270 ? -40.24832 -135.17049 0.73178   1.000 39.73480  ? 269 TRP A CB  1 
ATOM   1838 C CG  . TRP A 1 270 ? -39.45976 -135.14334 -0.53493  1.000 43.71314  ? 269 TRP A CG  1 
ATOM   1839 C CD1 . TRP A 1 270 ? -38.52535 -134.21971 -0.90501  1.000 40.77199  ? 269 TRP A CD1 1 
ATOM   1840 C CD2 . TRP A 1 270 ? -39.53346 -136.09196 -1.60131  1.000 41.40525  ? 269 TRP A CD2 1 
ATOM   1841 N NE1 . TRP A 1 270 ? -38.01276 -134.53663 -2.14144  1.000 45.54873  ? 269 TRP A NE1 1 
ATOM   1842 C CE2 . TRP A 1 270 ? -38.61566 -135.68257 -2.58944  1.000 43.69465  ? 269 TRP A CE2 1 
ATOM   1843 C CE3 . TRP A 1 270 ? -40.28599 -137.25033 -1.81674  1.000 44.47739  ? 269 TRP A CE3 1 
ATOM   1844 C CZ2 . TRP A 1 270 ? -38.43314 -136.38744 -3.77552  1.000 42.77372  ? 269 TRP A CZ2 1 
ATOM   1845 C CZ3 . TRP A 1 270 ? -40.10200 -137.95050 -2.99579  1.000 43.17703  ? 269 TRP A CZ3 1 
ATOM   1846 C CH2 . TRP A 1 270 ? -39.18228 -137.51547 -3.96036  1.000 43.30925  ? 269 TRP A CH2 1 
ATOM   1847 N N   . CYS A 1 271 ? -42.09820 -132.69537 1.14954   1.000 37.40719  ? 270 CYS A N   1 
ATOM   1848 C CA  . CYS A 1 271 ? -42.86173 -131.54628 0.66781   1.000 38.47065  ? 270 CYS A CA  1 
ATOM   1849 C C   . CYS A 1 271 ? -42.48914 -130.26866 1.40507   1.000 38.16407  ? 270 CYS A C   1 
ATOM   1850 O O   . CYS A 1 271 ? -42.57681 -129.17411 0.83387   1.000 35.72688  ? 270 CYS A O   1 
ATOM   1851 C CB  . CYS A 1 271 ? -44.36318 -131.80227 0.81603   1.000 37.32571  ? 270 CYS A CB  1 
ATOM   1852 S SG  . CYS A 1 271 ? -45.03370 -133.06952 -0.27539  1.000 36.06577  ? 270 CYS A SG  1 
ATOM   1853 N N   . LEU A 1 272 ? -42.08484 -130.38124 2.67118   1.000 33.85313  ? 271 LEU A N   1 
ATOM   1854 C CA  . LEU A 1 272 ? -41.74491 -129.22358 3.48539   1.000 36.68090  ? 271 LEU A CA  1 
ATOM   1855 C C   . LEU A 1 272 ? -40.24451 -128.95720 3.51519   1.000 36.96023  ? 271 LEU A C   1 
ATOM   1856 O O   . LEU A 1 272 ? -39.74148 -128.35495 4.46633   1.000 38.61182  ? 271 LEU A O   1 
ATOM   1857 C CB  . LEU A 1 272 ? -42.29108 -129.39291 4.90334   1.000 38.27036  ? 271 LEU A CB  1 
ATOM   1858 C CG  . LEU A 1 272 ? -43.81577 -129.52898 4.98039   1.000 38.36812  ? 271 LEU A CG  1 
ATOM   1859 C CD1 . LEU A 1 272 ? -44.29642 -129.60645 6.43263   1.000 34.95260  ? 271 LEU A CD1 1 
ATOM   1860 C CD2 . LEU A 1 272 ? -44.50266 -128.38382 4.23818   1.000 33.31441  ? 271 LEU A CD2 1 
ATOM   1861 N N   . ALA A 1 273 ? -39.51875 -129.38891 2.48743   1.000 41.46025  ? 272 ALA A N   1 
ATOM   1862 C CA  . ALA A 1 273 ? -38.10672 -129.04668 2.38768   1.000 40.97987  ? 272 ALA A CA  1 
ATOM   1863 C C   . ALA A 1 273 ? -37.94412 -127.53450 2.30979   1.000 42.03235  ? 272 ALA A C   1 
ATOM   1864 O O   . ALA A 1 273 ? -38.66486 -126.85362 1.57497   1.000 41.94713  ? 272 ALA A O   1 
ATOM   1865 C CB  . ALA A 1 273 ? -37.47801 -129.71261 1.16145   1.000 41.69892  ? 272 ALA A CB  1 
ATOM   1866 N N   . LEU A 1 274 ? -36.99376 -127.00912 3.08736   1.000 38.96330  ? 273 LEU A N   1 
ATOM   1867 C CA  . LEU A 1 274 ? -36.77106 -125.56581 3.12070   1.000 43.22612  ? 273 LEU A CA  1 
ATOM   1868 C C   . LEU A 1 274 ? -36.32776 -125.03614 1.76141   1.000 43.88907  ? 273 LEU A C   1 
ATOM   1869 O O   . LEU A 1 274 ? -36.80067 -123.98506 1.31275   1.000 45.37488  ? 273 LEU A O   1 
ATOM   1870 C CB  . LEU A 1 274 ? -35.73836 -125.21905 4.19523   1.000 44.17456  ? 273 LEU A CB  1 
ATOM   1871 C CG  . LEU A 1 274 ? -36.19600 -125.41381 5.64226   1.000 46.85705  ? 273 LEU A CG  1 
ATOM   1872 C CD1 . LEU A 1 274 ? -35.06521 -125.12345 6.61625   1.000 47.76219  ? 273 LEU A CD1 1 
ATOM   1873 C CD2 . LEU A 1 274 ? -37.40566 -124.53817 5.94121   1.000 46.33695  ? 273 LEU A CD2 1 
ATOM   1874 N N   . ARG A 1 275 ? -35.42164 -125.74048 1.09481   1.000 45.56385  ? 274 ARG A N   1 
ATOM   1875 C CA  . ARG A 1 275 ? -34.99027 -125.33028 -0.23580  1.000 47.96101  ? 274 ARG A CA  1 
ATOM   1876 C C   . ARG A 1 275 ? -36.04354 -125.74298 -1.25623  1.000 47.42791  ? 274 ARG A C   1 
ATOM   1877 O O   . ARG A 1 275 ? -36.40032 -126.92515 -1.31488  1.000 46.09402  ? 274 ARG A O   1 
ATOM   1878 C CB  . ARG A 1 275 ? -33.64427 -125.95318 -0.58328  1.000 51.05392  ? 274 ARG A CB  1 
ATOM   1879 N N   . PRO A 1 276 ? -36.57361 -124.81318 -2.05909  1.000 45.53602  ? 275 PRO A N   1 
ATOM   1880 C CA  . PRO A 1 276 ? -37.62497 -125.19182 -3.02249  1.000 47.95588  ? 275 PRO A CA  1 
ATOM   1881 C C   . PRO A 1 276 ? -37.21124 -126.29651 -3.98003  1.000 48.21095  ? 275 PRO A C   1 
ATOM   1882 O O   . PRO A 1 276 ? -38.02224 -127.18119 -4.27996  1.000 44.00362  ? 275 PRO A O   1 
ATOM   1883 C CB  . PRO A 1 276 ? -37.90521 -123.87664 -3.76448  1.000 44.75456  ? 275 PRO A CB  1 
ATOM   1884 C CG  . PRO A 1 276 ? -37.50915 -122.80957 -2.79807  1.000 49.14942  ? 275 PRO A CG  1 
ATOM   1885 C CD  . PRO A 1 276 ? -36.33184 -123.36061 -2.03890  1.000 45.37690  ? 275 PRO A CD  1 
ATOM   1886 N N   . SER A 1 277 ? -35.96673 -126.27902 -4.46463  1.000 49.28845  ? 276 SER A N   1 
ATOM   1887 C CA  . SER A 1 277 ? -35.53085 -127.28972 -5.42245  1.000 50.20560  ? 276 SER A CA  1 
ATOM   1888 C C   . SER A 1 277 ? -35.43290 -128.67785 -4.80110  1.000 48.61668  ? 276 SER A C   1 
ATOM   1889 O O   . SER A 1 277 ? -35.40336 -129.66976 -5.53736  1.000 50.51421  ? 276 SER A O   1 
ATOM   1890 C CB  . SER A 1 277 ? -34.18506 -126.89237 -6.03288  1.000 50.72102  ? 276 SER A CB  1 
ATOM   1891 O OG  . SER A 1 277 ? -33.19546 -126.72805 -5.02957  1.000 54.53811  ? 276 SER A OG  1 
ATOM   1892 N N   . ASP A 1 278 ? -35.38037 -128.77228 -3.47118  1.000 48.66951  ? 277 ASP A N   1 
ATOM   1893 C CA  . ASP A 1 278 ? -35.38447 -130.06456 -2.79605  1.000 48.90904  ? 277 ASP A CA  1 
ATOM   1894 C C   . ASP A 1 278 ? -36.77767 -130.66858 -2.66209  1.000 45.59639  ? 277 ASP A C   1 
ATOM   1895 O O   . ASP A 1 278 ? -36.88923 -131.83867 -2.28197  1.000 47.42470  ? 277 ASP A O   1 
ATOM   1896 C CB  . ASP A 1 278 ? -34.76175 -129.94191 -1.40368  1.000 46.43890  ? 277 ASP A CB  1 
ATOM   1897 C CG  . ASP A 1 278 ? -33.25807 -129.75471 -1.44768  1.000 54.04186  ? 277 ASP A CG  1 
ATOM   1898 O OD1 . ASP A 1 278 ? -32.64383 -130.09040 -2.48172  1.000 54.25055  ? 277 ASP A OD1 1 
ATOM   1899 O OD2 . ASP A 1 278 ? -32.69258 -129.28359 -0.43833  1.000 52.80811  ? 277 ASP A OD2 1 
ATOM   1900 N N   . ARG A 1 279 ? -37.83435 -129.90865 -2.95125  1.000 44.22089  ? 278 ARG A N   1 
ATOM   1901 C CA  . ARG A 1 279 ? -39.18653 -130.42766 -2.82629  1.000 38.93333  ? 278 ARG A CA  1 
ATOM   1902 C C   . ARG A 1 279 ? -39.52667 -131.32897 -4.01175  1.000 44.00484  ? 278 ARG A C   1 
ATOM   1903 O O   . ARG A 1 279 ? -38.99683 -131.14751 -5.11318  1.000 45.25121  ? 278 ARG A O   1 
ATOM   1904 C CB  . ARG A 1 279 ? -40.19038 -129.28041 -2.73454  1.000 39.02227  ? 278 ARG A CB  1 
ATOM   1905 C CG  . ARG A 1 279 ? -40.05831 -128.46557 -1.45306  1.000 38.68140  ? 278 ARG A CG  1 
ATOM   1906 C CD  . ARG A 1 279 ? -40.85204 -127.16713 -1.49681  1.000 38.35261  ? 278 ARG A CD  1 
ATOM   1907 N NE  . ARG A 1 279 ? -40.32973 -126.21632 -0.52183  1.000 40.65137  ? 278 ARG A NE  1 
ATOM   1908 C CZ  . ARG A 1 279 ? -40.51521 -124.90434 -0.57090  1.000 41.81082  ? 278 ARG A CZ  1 
ATOM   1909 N NH1 . ARG A 1 279 ? -41.25708 -124.34430 -1.51375  1.000 37.65328  ? 278 ARG A NH1 1 
ATOM   1910 N NH2 . ARG A 1 279 ? -39.92692 -124.13283 0.33932   1.000 41.36170  ? 278 ARG A NH2 1 
ATOM   1911 N N   . PRO A 1 280 ? -40.40251 -132.30854 -3.81123  1.000 42.29492  ? 279 PRO A N   1 
ATOM   1912 C CA  . PRO A 1 280 ? -40.75583 -133.22071 -4.90114  1.000 37.99489  ? 279 PRO A CA  1 
ATOM   1913 C C   . PRO A 1 280 ? -41.66318 -132.55847 -5.92611  1.000 41.20747  ? 279 PRO A C   1 
ATOM   1914 O O   . PRO A 1 280 ? -42.38073 -131.59855 -5.63956  1.000 40.18787  ? 279 PRO A O   1 
ATOM   1915 C CB  . PRO A 1 280 ? -41.49012 -134.35593 -4.18169  1.000 38.11191  ? 279 PRO A CB  1 
ATOM   1916 C CG  . PRO A 1 280 ? -42.11896 -133.67835 -3.00649  1.000 42.26812  ? 279 PRO A CG  1 
ATOM   1917 C CD  . PRO A 1 280 ? -41.13093 -132.62644 -2.56873  1.000 40.71416  ? 279 PRO A CD  1 
ATOM   1918 N N   . THR A 1 281 ? -41.61207 -133.09496 -7.14495  1.000 39.61266  ? 280 THR A N   1 
ATOM   1919 C CA  . THR A 1 281 ? -42.58993 -132.75381 -8.16486  1.000 40.07944  ? 280 THR A CA  1 
ATOM   1920 C C   . THR A 1 281 ? -43.89403 -133.49943 -7.89670  1.000 40.81613  ? 280 THR A C   1 
ATOM   1921 O O   . THR A 1 281 ? -43.95899 -134.40760 -7.06296  1.000 41.59732  ? 280 THR A O   1 
ATOM   1922 C CB  . THR A 1 281 ? -42.07376 -133.10762 -9.56016  1.000 40.56498  ? 280 THR A CB  1 
ATOM   1923 O OG1 . THR A 1 281 ? -41.96537 -134.53254 -9.68013  1.000 38.55266  ? 280 THR A OG1 1 
ATOM   1924 C CG2 . THR A 1 281 ? -40.70967 -132.47663 -9.81284  1.000 42.70895  ? 280 THR A CG2 1 
ATOM   1925 N N   . PHE A 1 282 ? -44.94525 -133.11308 -8.62611  1.000 39.38699  ? 281 PHE A N   1 
ATOM   1926 C CA  . PHE A 1 282 ? -46.21780 -133.81679 -8.49965  1.000 41.20869  ? 281 PHE A CA  1 
ATOM   1927 C C   . PHE A 1 282 ? -46.06057 -135.29544 -8.83154  1.000 40.38001  ? 281 PHE A C   1 
ATOM   1928 O O   . PHE A 1 282 ? -46.64273 -136.15430 -8.15859  1.000 36.84219  ? 281 PHE A O   1 
ATOM   1929 C CB  . PHE A 1 282 ? -47.27047 -133.16980 -9.39949  1.000 40.36293  ? 281 PHE A CB  1 
ATOM   1930 C CG  . PHE A 1 282 ? -47.64854 -131.77491 -8.98591  1.000 41.72554  ? 281 PHE A CG  1 
ATOM   1931 C CD1 . PHE A 1 282 ? -47.75556 -131.43896 -7.64947  1.000 48.72552  ? 281 PHE A CD1 1 
ATOM   1932 C CD2 . PHE A 1 282 ? -47.89505 -130.79873 -9.93670  1.000 51.24575  ? 281 PHE A CD2 1 
ATOM   1933 C CE1 . PHE A 1 282 ? -48.10475 -130.15316 -7.26392  1.000 45.59077  ? 281 PHE A CE1 1 
ATOM   1934 C CE2 . PHE A 1 282 ? -48.24265 -129.51295 -9.55768  1.000 49.11154  ? 281 PHE A CE2 1 
ATOM   1935 C CZ  . PHE A 1 282 ? -48.34330 -129.19134 -8.21836  1.000 45.03508  ? 281 PHE A CZ  1 
ATOM   1936 N N   . GLU A 1 283 ? -45.26168 -135.61026 -9.85781  1.000 39.09312  ? 282 GLU A N   1 
ATOM   1937 C CA  . GLU A 1 283 ? -45.01675 -137.00421 -10.21796 1.000 39.76044  ? 282 GLU A CA  1 
ATOM   1938 C C   . GLU A 1 283 ? -44.32868 -137.75435 -9.08563  1.000 36.86130  ? 282 GLU A C   1 
ATOM   1939 O O   . GLU A 1 283 ? -44.70055 -138.88926 -8.76635  1.000 39.52692  ? 282 GLU A O   1 
ATOM   1940 C CB  . GLU A 1 283 ? -44.17554 -137.07891 -11.49580 1.000 38.61602  ? 282 GLU A CB  1 
ATOM   1941 C CG  . GLU A 1 283 ? -43.77529 -138.49682 -11.89472 1.000 39.22605  ? 282 GLU A CG  1 
ATOM   1942 C CD  . GLU A 1 283 ? -42.92501 -138.54812 -13.16004 1.000 53.91179  ? 282 GLU A CD  1 
ATOM   1943 O OE1 . GLU A 1 283 ? -42.35459 -137.50540 -13.54911 1.000 49.91928  ? 282 GLU A OE1 1 
ATOM   1944 O OE2 . GLU A 1 283 ? -42.82590 -139.63839 -13.76428 1.000 51.83927  ? 282 GLU A OE2 1 
ATOM   1945 N N   . GLU A 1 284 ? -43.32304 -137.13427 -8.46450  1.000 38.66471  ? 283 GLU A N   1 
ATOM   1946 C CA  . GLU A 1 284 ? -42.62227 -137.78275 -7.36171  1.000 41.59130  ? 283 GLU A CA  1 
ATOM   1947 C C   . GLU A 1 284 ? -43.53279 -137.99470 -6.15822  1.000 39.33215  ? 283 GLU A C   1 
ATOM   1948 O O   . GLU A 1 284 ? -43.39030 -138.99673 -5.44904  1.000 40.33499  ? 283 GLU A O   1 
ATOM   1949 C CB  . GLU A 1 284 ? -41.39186 -136.96511 -6.96814  1.000 40.77519  ? 283 GLU A CB  1 
ATOM   1950 C CG  . GLU A 1 284 ? -40.25586 -137.04505 -7.98308  1.000 44.97403  ? 283 GLU A CG  1 
ATOM   1951 C CD  . GLU A 1 284 ? -39.09985 -136.13034 -7.63672  1.000 41.46044  ? 283 GLU A CD  1 
ATOM   1952 O OE1 . GLU A 1 284 ? -39.34185 -134.93285 -7.38623  1.000 45.23960  ? 283 GLU A OE1 1 
ATOM   1953 O OE2 . GLU A 1 284 ? -37.95190 -136.61298 -7.60238  1.000 47.29073  ? 283 GLU A OE2 1 
ATOM   1954 N N   . ILE A 1 285 ? -44.47221 -137.07891 -5.91412  1.000 37.75993  ? 284 ILE A N   1 
ATOM   1955 C CA  . ILE A 1 285 ? -45.41160 -137.26579 -4.81107  1.000 40.07931  ? 284 ILE A CA  1 
ATOM   1956 C C   . ILE A 1 285 ? -46.30625 -138.47028 -5.07523  1.000 38.19854  ? 284 ILE A C   1 
ATOM   1957 O O   . ILE A 1 285 ? -46.47213 -139.34273 -4.21575  1.000 37.38434  ? 284 ILE A O   1 
ATOM   1958 C CB  . ILE A 1 285 ? -46.24171 -135.98982 -4.58092  1.000 41.64790  ? 284 ILE A CB  1 
ATOM   1959 C CG1 . ILE A 1 285 ? -45.34761 -134.84668 -4.10083  1.000 35.41535  ? 284 ILE A CG1 1 
ATOM   1960 C CG2 . ILE A 1 285 ? -47.35404 -136.25426 -3.57197  1.000 34.44230  ? 284 ILE A CG2 1 
ATOM   1961 C CD1 . ILE A 1 285 ? -46.07140 -133.52080 -3.98070  1.000 36.76850  ? 284 ILE A CD1 1 
ATOM   1962 N N   . GLN A 1 286 ? -46.88125 -138.54725 -6.27640  1.000 38.74808  ? 285 GLN A N   1 
ATOM   1963 C CA  . GLN A 1 286 ? -47.81110 -139.62675 -6.58214  1.000 38.31448  ? 285 GLN A CA  1 
ATOM   1964 C C   . GLN A 1 286 ? -47.11212 -140.96665 -6.77450  1.000 36.23484  ? 285 GLN A C   1 
ATOM   1965 O O   . GLN A 1 286 ? -47.77107 -142.00781 -6.68987  1.000 40.87797  ? 285 GLN A O   1 
ATOM   1966 C CB  . GLN A 1 286 ? -48.63963 -139.26059 -7.81484  1.000 35.66663  ? 285 GLN A CB  1 
ATOM   1967 C CG  . GLN A 1 286 ? -49.52539 -138.04295 -7.57980  1.000 37.91839  ? 285 GLN A CG  1 
ATOM   1968 C CD  . GLN A 1 286 ? -50.51302 -137.80172 -8.69938  1.000 37.63290  ? 285 GLN A CD  1 
ATOM   1969 O OE1 . GLN A 1 286 ? -50.14079 -137.37081 -9.79011  1.000 36.06028  ? 285 GLN A OE1 1 
ATOM   1970 N NE2 . GLN A 1 286 ? -51.78365 -138.08086 -8.43487  1.000 36.91131  ? 285 GLN A NE2 1 
ATOM   1971 N N   . ASN A 1 287 ? -45.80298 -140.97031 -7.01879  1.000 36.95185  ? 286 ASN A N   1 
ATOM   1972 C CA  . ASN A 1 287 ? -45.02449 -142.20300 -7.05086  1.000 36.85417  ? 286 ASN A CA  1 
ATOM   1973 C C   . ASN A 1 287 ? -44.46100 -142.58461 -5.68640  1.000 42.18974  ? 286 ASN A C   1 
ATOM   1974 O O   . ASN A 1 287 ? -43.79782 -143.62139 -5.57640  1.000 41.14302  ? 286 ASN A O   1 
ATOM   1975 C CB  . ASN A 1 287 ? -43.87162 -142.08518 -8.05640  1.000 38.97029  ? 286 ASN A CB  1 
ATOM   1976 C CG  . ASN A 1 287 ? -44.33919 -142.17385 -9.49778  1.000 45.19593  ? 286 ASN A CG  1 
ATOM   1977 O OD1 . ASN A 1 287 ? -45.33211 -142.83445 -9.80332  1.000 44.50878  ? 286 ASN A OD1 1 
ATOM   1978 N ND2 . ASN A 1 287 ? -43.61982 -141.50913 -10.39230 1.000 43.61378  ? 286 ASN A ND2 1 
ATOM   1979 N N   . HIS A 1 288 ? -44.69821 -141.77532 -4.65647  1.000 40.63159  ? 287 HIS A N   1 
ATOM   1980 C CA  . HIS A 1 288 ? -44.16870 -142.07456 -3.33393  1.000 40.27116  ? 287 HIS A CA  1 
ATOM   1981 C C   . HIS A 1 288 ? -44.82765 -143.33723 -2.78115  1.000 41.16933  ? 287 HIS A C   1 
ATOM   1982 O O   . HIS A 1 288 ? -46.02902 -143.54647 -2.97794  1.000 41.27222  ? 287 HIS A O   1 
ATOM   1983 C CB  . HIS A 1 288 ? -44.40514 -140.89636 -2.38547  1.000 39.68137  ? 287 HIS A CB  1 
ATOM   1984 C CG  . HIS A 1 288 ? -43.68307 -141.00895 -1.07570  1.000 40.58215  ? 287 HIS A CG  1 
ATOM   1985 N ND1 . HIS A 1 288 ? -44.17971 -141.72831 -0.00969  1.000 36.56449  ? 287 HIS A ND1 1 
ATOM   1986 C CD2 . HIS A 1 288 ? -42.50666 -140.48365 -0.65811  1.000 38.39956  ? 287 HIS A CD2 1 
ATOM   1987 C CE1 . HIS A 1 288 ? -43.33891 -141.64490 1.00674   1.000 40.55755  ? 287 HIS A CE1 1 
ATOM   1988 N NE2 . HIS A 1 288 ? -42.31484 -140.89583 0.63958   1.000 40.52577  ? 287 HIS A NE2 1 
ATOM   1989 N N   . PRO A 1 289 ? -44.06870 -144.19627 -2.09518  1.000 41.81428  ? 288 PRO A N   1 
ATOM   1990 C CA  . PRO A 1 289 ? -44.65454 -145.43152 -1.54451  1.000 45.43967  ? 288 PRO A CA  1 
ATOM   1991 C C   . PRO A 1 289 ? -45.91135 -145.21565 -0.71524  1.000 41.88433  ? 288 PRO A C   1 
ATOM   1992 O O   . PRO A 1 289 ? -46.81580 -146.05942 -0.75457  1.000 42.44235  ? 288 PRO A O   1 
ATOM   1993 C CB  . PRO A 1 289 ? -43.51070 -145.99993 -0.69345  1.000 43.85111  ? 288 PRO A CB  1 
ATOM   1994 C CG  . PRO A 1 289 ? -42.27549 -145.50511 -1.37146  1.000 47.38280  ? 288 PRO A CG  1 
ATOM   1995 C CD  . PRO A 1 289 ? -42.61263 -144.12912 -1.88336  1.000 44.43387  ? 288 PRO A CD  1 
ATOM   1996 N N   . TRP A 1 290 ? -46.01148 -144.10732 0.02142   1.000 36.76594  ? 289 TRP A N   1 
ATOM   1997 C CA  . TRP A 1 290 ? -47.19672 -143.88399 0.84318   1.000 40.15003  ? 289 TRP A CA  1 
ATOM   1998 C C   . TRP A 1 290 ? -48.44992 -143.63163 0.01214   1.000 40.45494  ? 289 TRP A C   1 
ATOM   1999 O O   . TRP A 1 290 ? -49.56138 -143.80220 0.52429   1.000 41.48999  ? 289 TRP A O   1 
ATOM   2000 C CB  . TRP A 1 290 ? -46.97165 -142.71387 1.80703   1.000 38.18066  ? 289 TRP A CB  1 
ATOM   2001 C CG  . TRP A 1 290 ? -48.14279 -142.48543 2.71806   1.000 40.25569  ? 289 TRP A CG  1 
ATOM   2002 C CD1 . TRP A 1 290 ? -48.45305 -143.18971 3.84470   1.000 37.96505  ? 289 TRP A CD1 1 
ATOM   2003 C CD2 . TRP A 1 290 ? -49.17097 -141.49866 2.56568   1.000 37.35021  ? 289 TRP A CD2 1 
ATOM   2004 N NE1 . TRP A 1 290 ? -49.60847 -142.70203 4.40365   1.000 38.90642  ? 289 TRP A NE1 1 
ATOM   2005 C CE2 . TRP A 1 290 ? -50.06781 -141.66156 3.63920   1.000 39.94513  ? 289 TRP A CE2 1 
ATOM   2006 C CE3 . TRP A 1 290 ? -49.41836 -140.49204 1.62669   1.000 37.51056  ? 289 TRP A CE3 1 
ATOM   2007 C CZ2 . TRP A 1 290 ? -51.19434 -140.85497 3.80090   1.000 38.10361  ? 289 TRP A CZ2 1 
ATOM   2008 C CZ3 . TRP A 1 290 ? -50.53566 -139.69083 1.78942   1.000 33.97763  ? 289 TRP A CZ3 1 
ATOM   2009 C CH2 . TRP A 1 290 ? -51.40805 -139.87580 2.86865   1.000 37.19587  ? 289 TRP A CH2 1 
ATOM   2010 N N   . MET A 1 291 ? -48.30375 -143.24951 -1.25372  1.000 38.84606  ? 290 MET A N   1 
ATOM   2011 C CA  . MET A 1 291 ? -49.43725 -142.87789 -2.08904  1.000 40.32789  ? 290 MET A CA  1 
ATOM   2012 C C   . MET A 1 291 ? -49.98572 -144.03235 -2.91436  1.000 41.92771  ? 290 MET A C   1 
ATOM   2013 O O   . MET A 1 291 ? -50.88674 -143.81670 -3.73112  1.000 43.97024  ? 290 MET A O   1 
ATOM   2014 C CB  . MET A 1 291 ? -49.04572 -141.72606 -3.01572  1.000 39.71446  ? 290 MET A CB  1 
ATOM   2015 C CG  . MET A 1 291 ? -48.78674 -140.42127 -2.27946  1.000 40.12073  ? 290 MET A CG  1 
ATOM   2016 S SD  . MET A 1 291 ? -50.08955 -139.20730 -2.54580  1.000 45.05617  ? 290 MET A SD  1 
ATOM   2017 C CE  . MET A 1 291 ? -51.49476 -139.99366 -1.77047  1.000 34.54209  ? 290 MET A CE  1 
ATOM   2018 N N   . GLN A 1 292 ? -49.47691 -145.24195 -2.72437  1.000 42.34895  ? 291 GLN A N   1 
ATOM   2019 C CA  . GLN A 1 292 ? -49.89167 -146.37052 -3.54295  1.000 47.44392  ? 291 GLN A CA  1 
ATOM   2020 C C   . GLN A 1 292 ? -51.17296 -147.00208 -3.00090  1.000 49.18699  ? 291 GLN A C   1 
ATOM   2021 O O   . GLN A 1 292 ? -51.50921 -146.87271 -1.82000  1.000 44.38691  ? 291 GLN A O   1 
ATOM   2022 C CB  . GLN A 1 292 ? -48.77129 -147.40725 -3.61802  1.000 46.51857  ? 291 GLN A CB  1 
ATOM   2023 C CG  . GLN A 1 292 ? -47.47948 -146.83693 -4.18219  1.000 47.53512  ? 291 GLN A CG  1 
ATOM   2024 C CD  . GLN A 1 292 ? -47.71276 -146.00810 -5.43818  1.000 56.73780  ? 291 GLN A CD  1 
ATOM   2025 O OE1 . GLN A 1 292 ? -48.14228 -146.52869 -6.47023  1.000 56.12994  ? 291 GLN A OE1 1 
ATOM   2026 N NE2 . GLN A 1 292 ? -47.43757 -144.70792 -5.35123  1.000 47.57027  ? 291 GLN A NE2 1 
ATOM   2027 N N   . ASP A 1 293 ? -51.90024 -147.67391 -3.90052  1.000 44.80800  ? 292 ASP A N   1 
ATOM   2028 C CA  . ASP A 1 293 ? -53.13792 -148.38395 -3.56221  1.000 51.05060  ? 292 ASP A CA  1 
ATOM   2029 C C   . ASP A 1 293 ? -54.20478 -147.43660 -3.01525  1.000 44.96419  ? 292 ASP A C   1 
ATOM   2030 O O   . ASP A 1 293 ? -54.89346 -147.74570 -2.04196  1.000 50.35586  ? 292 ASP A O   1 
ATOM   2031 C CB  . ASP A 1 293 ? -52.87286 -149.52308 -2.57389  1.000 54.51488  ? 292 ASP A CB  1 
ATOM   2032 C CG  . ASP A 1 293 ? -51.82382 -150.48988 -3.07232  1.000 60.13772  ? 292 ASP A CG  1 
ATOM   2033 O OD1 . ASP A 1 293 ? -51.84975 -150.82532 -4.27402  1.000 64.87818  ? 292 ASP A OD1 1 
ATOM   2034 O OD2 . ASP A 1 293 ? -50.96642 -150.90382 -2.26526  1.000 68.85214  ? 292 ASP A OD2 1 
ATOM   2035 N N   . VAL A 1 294 ? -54.35522 -146.27706 -3.65510  1.000 42.06725  ? 293 VAL A N   1 
ATOM   2036 C CA  . VAL A 1 294 ? -55.35170 -145.30802 -3.21750  1.000 41.44553  ? 293 VAL A CA  1 
ATOM   2037 C C   . VAL A 1 294 ? -56.75273 -145.85952 -3.45884  1.000 46.21783  ? 293 VAL A C   1 
ATOM   2038 O O   . VAL A 1 294 ? -57.00017 -146.58478 -4.43383  1.000 45.56760  ? 293 VAL A O   1 
ATOM   2039 C CB  . VAL A 1 294 ? -55.14154 -143.96489 -3.93921  1.000 42.95550  ? 293 VAL A CB  1 
ATOM   2040 C CG1 . VAL A 1 294 ? -55.32187 -144.12881 -5.44969  1.000 43.88943  ? 293 VAL A CG1 1 
ATOM   2041 C CG2 . VAL A 1 294 ? -56.09013 -142.90412 -3.39530  1.000 38.12374  ? 293 VAL A CG2 1 
ATOM   2042 N N   . LEU A 1 295 ? -57.67628 -145.53139 -2.55746  1.000 40.76400  ? 294 LEU A N   1 
ATOM   2043 C CA  . LEU A 1 295 ? -59.07053 -145.91416 -2.73229  1.000 43.58707  ? 294 LEU A CA  1 
ATOM   2044 C C   . LEU A 1 295 ? -59.73051 -145.08185 -3.82621  1.000 42.77737  ? 294 LEU A C   1 
ATOM   2045 O O   . LEU A 1 295 ? -59.37737 -143.92192 -4.05712  1.000 41.39501  ? 294 LEU A O   1 
ATOM   2046 C CB  . LEU A 1 295 ? -59.85203 -145.73152 -1.42990  1.000 40.98648  ? 294 LEU A CB  1 
ATOM   2047 C CG  . LEU A 1 295 ? -59.55085 -146.60275 -0.20944  1.000 39.75268  ? 294 LEU A CG  1 
ATOM   2048 C CD1 . LEU A 1 295 ? -60.40869 -146.14095 0.96434   1.000 47.28307  ? 294 LEU A CD1 1 
ATOM   2049 C CD2 . LEU A 1 295 ? -59.80522 -148.06928 -0.50363  1.000 45.03429  ? 294 LEU A CD2 1 
ATOM   2050 N N   . LEU A 1 296 ? -60.71132 -145.68639 -4.49280  1.000 43.04017  ? 295 LEU A N   1 
ATOM   2051 C CA  . LEU A 1 296 ? -61.55677 -144.95367 -5.41836  1.000 44.49852  ? 295 LEU A CA  1 
ATOM   2052 C C   . LEU A 1 296 ? -62.46585 -144.00231 -4.64214  1.000 45.72857  ? 295 LEU A C   1 
ATOM   2053 O O   . LEU A 1 296 ? -62.71670 -144.20564 -3.45159  1.000 42.69694  ? 295 LEU A O   1 
ATOM   2054 C CB  . LEU A 1 296 ? -62.39424 -145.92083 -6.25354  1.000 45.46766  ? 295 LEU A CB  1 
ATOM   2055 C CG  . LEU A 1 296 ? -61.64342 -147.00321 -7.03471  1.000 51.56260  ? 295 LEU A CG  1 
ATOM   2056 C CD1 . LEU A 1 296 ? -62.60514 -147.82724 -7.88283  1.000 52.10718  ? 295 LEU A CD1 1 
ATOM   2057 C CD2 . LEU A 1 296 ? -60.55244 -146.39014 -7.89929  1.000 49.60848  ? 295 LEU A CD2 1 
ATOM   2058 N N   . PRO A 1 297 ? -62.96037 -142.94232 -5.29204  1.000 44.39506  ? 296 PRO A N   1 
ATOM   2059 C CA  . PRO A 1 297 ? -63.87094 -142.02362 -4.58325  1.000 44.05904  ? 296 PRO A CA  1 
ATOM   2060 C C   . PRO A 1 297 ? -65.09949 -142.71389 -4.01490  1.000 49.47933  ? 296 PRO A C   1 
ATOM   2061 O O   . PRO A 1 297 ? -65.46870 -142.45560 -2.86114  1.000 45.81301  ? 296 PRO A O   1 
ATOM   2062 C CB  . PRO A 1 297 ? -64.24001 -140.99831 -5.66348  1.000 46.10529  ? 296 PRO A CB  1 
ATOM   2063 C CG  . PRO A 1 297 ? -63.08503 -141.02908 -6.61913  1.000 45.53609  ? 296 PRO A CG  1 
ATOM   2064 C CD  . PRO A 1 297 ? -62.62581 -142.45933 -6.64418  1.000 46.27043  ? 296 PRO A CD  1 
ATOM   2065 N N   . GLN A 1 298 ? -65.73728 -143.59681 -4.79138  1.000 45.57282  ? 297 GLN A N   1 
ATOM   2066 C CA  . GLN A 1 298 ? -66.90940 -144.31310 -4.29384  1.000 48.45427  ? 297 GLN A CA  1 
ATOM   2067 C C   . GLN A 1 298 ? -66.55901 -145.19233 -3.09763  1.000 50.42700  ? 297 GLN A C   1 
ATOM   2068 O O   . GLN A 1 298 ? -67.32935 -145.27672 -2.13354  1.000 49.66687  ? 297 GLN A O   1 
ATOM   2069 C CB  . GLN A 1 298 ? -67.52603 -145.15234 -5.41297  1.000 52.03282  ? 297 GLN A CB  1 
ATOM   2070 N N   . GLU A 1 299 ? -65.40505 -145.86399 -3.14583  1.000 47.34652  ? 298 GLU A N   1 
ATOM   2071 C CA  . GLU A 1 299 ? -64.95861 -146.64882 -1.99932  1.000 49.47195  ? 298 GLU A CA  1 
ATOM   2072 C C   . GLU A 1 299 ? -64.71046 -145.75841 -0.78997  1.000 47.93700  ? 298 GLU A C   1 
ATOM   2073 O O   . GLU A 1 299 ? -64.98518 -146.15301 0.35008   1.000 48.80826  ? 298 GLU A O   1 
ATOM   2074 C CB  . GLU A 1 299 ? -63.68829 -147.42290 -2.35012  1.000 48.07306  ? 298 GLU A CB  1 
ATOM   2075 C CG  . GLU A 1 299 ? -63.85540 -148.45786 -3.44315  1.000 50.96509  ? 298 GLU A CG  1 
ATOM   2076 C CD  . GLU A 1 299 ? -62.53180 -149.07314 -3.85979  1.000 55.86848  ? 298 GLU A CD  1 
ATOM   2077 O OE1 . GLU A 1 299 ? -61.47707 -148.45197 -3.59822  1.000 49.38945  ? 298 GLU A OE1 1 
ATOM   2078 O OE2 . GLU A 1 299 ? -62.54667 -150.17663 -4.44803  1.000 63.33034  ? 298 GLU A OE2 1 
ATOM   2079 N N   . THR A 1 300 ? -64.18086 -144.55494 -1.02100  1.000 45.20254  ? 299 THR A N   1 
ATOM   2080 C CA  . THR A 1 300 ? -63.91693 -143.63392 0.07867   1.000 46.84472  ? 299 THR A CA  1 
ATOM   2081 C C   . THR A 1 300 ? -65.20731 -143.22989 0.77833   1.000 51.01283  ? 299 THR A C   1 
ATOM   2082 O O   . THR A 1 300 ? -65.26999 -143.19607 2.01431   1.000 47.76885  ? 299 THR A O   1 
ATOM   2083 C CB  . THR A 1 300 ? -63.18098 -142.39831 -0.43823  1.000 45.46034  ? 299 THR A CB  1 
ATOM   2084 O OG1 . THR A 1 300 ? -61.98516 -142.80230 -1.11804  1.000 40.11608  ? 299 THR A OG1 1 
ATOM   2085 C CG2 . THR A 1 300 ? -62.81682 -141.47698 0.71826   1.000 38.72967  ? 299 THR A CG2 1 
ATOM   2086 N N   . ALA A 1 301 ? -66.25033 -142.92751 0.00151   1.000 46.32199  ? 300 ALA A N   1 
ATOM   2087 C CA  . ALA A 1 301 ? -67.52277 -142.52817 0.58964   1.000 52.27823  ? 300 ALA A CA  1 
ATOM   2088 C C   . ALA A 1 301 ? -68.15769 -143.67337 1.36769   1.000 57.02007  ? 300 ALA A C   1 
ATOM   2089 O O   . ALA A 1 301 ? -68.67429 -143.46820 2.47146   1.000 54.76057  ? 300 ALA A O   1 
ATOM   2090 C CB  . ALA A 1 301 ? -68.46952 -142.02982 -0.50130  1.000 53.23816  ? 300 ALA A CB  1 
ATOM   2091 N N   . GLU A 1 302 ? -68.11814 -144.88873 0.81632   1.000 53.32379  ? 301 GLU A N   1 
ATOM   2092 C CA  . GLU A 1 302 ? -68.78430 -146.01387 1.46563   1.000 57.70719  ? 301 GLU A CA  1 
ATOM   2093 C C   . GLU A 1 302 ? -68.06532 -146.43224 2.74279   1.000 55.04239  ? 301 GLU A C   1 
ATOM   2094 O O   . GLU A 1 302 ? -68.70957 -146.82799 3.72043   1.000 52.82729  ? 301 GLU A O   1 
ATOM   2095 C CB  . GLU A 1 302 ? -68.88762 -147.19245 0.49812   1.000 55.08288  ? 301 GLU A CB  1 
ATOM   2096 C CG  . GLU A 1 302 ? -69.82747 -146.95250 -0.66840  1.000 59.30123  ? 301 GLU A CG  1 
ATOM   2097 C CD  . GLU A 1 302 ? -69.87144 -148.12338 -1.63010  1.000 69.96870  ? 301 GLU A CD  1 
ATOM   2098 O OE1 . GLU A 1 302 ? -68.97910 -148.99547 -1.54792  1.000 71.02922  ? 301 GLU A OE1 1 
ATOM   2099 O OE2 . GLU A 1 302 ? -70.80036 -148.17309 -2.46530  1.000 66.72471  ? 301 GLU A OE2 1 
ATOM   2100 N N   . ILE A 1 303 ? -66.73497 -146.35033 2.75839   1.000 52.92543  ? 302 ILE A N   1 
ATOM   2101 C CA  . ILE A 1 303 ? -65.98254 -146.82300 3.91618   1.000 49.31004  ? 302 ILE A CA  1 
ATOM   2102 C C   . ILE A 1 303 ? -65.89851 -145.74894 4.99310   1.000 50.55843  ? 302 ILE A C   1 
ATOM   2103 O O   . ILE A 1 303 ? -66.02359 -146.04316 6.18811   1.000 50.86674  ? 302 ILE A O   1 
ATOM   2104 C CB  . ILE A 1 303 ? -64.58375 -147.29799 3.48283   1.000 49.13104  ? 302 ILE A CB  1 
ATOM   2105 C CG1 . ILE A 1 303 ? -64.69333 -148.51765 2.56682   1.000 50.24427  ? 302 ILE A CG1 1 
ATOM   2106 C CG2 . ILE A 1 303 ? -63.72222 -147.61957 4.69957   1.000 50.07735  ? 302 ILE A CG2 1 
ATOM   2107 C CD1 . ILE A 1 303 ? -63.35613 -149.01330 2.05756   1.000 52.05318  ? 302 ILE A CD1 1 
ATOM   2108 N N   . HIS A 1 304 ? -65.69845 -144.49073 4.59818   1.000 48.69452  ? 303 HIS A N   1 
ATOM   2109 C CA  . HIS A 1 304 ? -65.37501 -143.43613 5.54763   1.000 50.99897  ? 303 HIS A CA  1 
ATOM   2110 C C   . HIS A 1 304 ? -66.42369 -142.34146 5.67572   1.000 51.10620  ? 303 HIS A C   1 
ATOM   2111 O O   . HIS A 1 304 ? -66.38916 -141.60286 6.66606   1.000 52.45039  ? 303 HIS A O   1 
ATOM   2112 C CB  . HIS A 1 304 ? -64.03502 -142.77917 5.17789   1.000 46.89175  ? 303 HIS A CB  1 
ATOM   2113 C CG  . HIS A 1 304 ? -62.86505 -143.71122 5.24686   1.000 46.66788  ? 303 HIS A CG  1 
ATOM   2114 N ND1 . HIS A 1 304 ? -62.22076 -144.01094 6.42785   1.000 46.83704  ? 303 HIS A ND1 1 
ATOM   2115 C CD2 . HIS A 1 304 ? -62.22192 -144.40877 4.28067   1.000 44.75175  ? 303 HIS A CD2 1 
ATOM   2116 C CE1 . HIS A 1 304 ? -61.23247 -144.85409 6.18723   1.000 45.42304  ? 303 HIS A CE1 1 
ATOM   2117 N NE2 . HIS A 1 304 ? -61.21132 -145.11143 4.89175   1.000 49.74583  ? 303 HIS A NE2 1 
ATOM   2118 N N   . LEU A 1 305 ? -67.34484 -142.20941 4.72566   1.000 52.87613  ? 304 LEU A N   1 
ATOM   2119 C CA  . LEU A 1 305 ? -68.28436 -141.09620 4.72990   1.000 56.88792  ? 304 LEU A CA  1 
ATOM   2120 C C   . LEU A 1 305 ? -69.74024 -141.50333 4.90672   1.000 62.24096  ? 304 LEU A C   1 
ATOM   2121 O O   . LEU A 1 305 ? -70.51811 -140.71624 5.44964   1.000 68.05658  ? 304 LEU A O   1 
ATOM   2122 C CB  . LEU A 1 305 ? -68.15022 -140.28329 3.43188   1.000 51.72006  ? 304 LEU A CB  1 
ATOM   2123 C CG  . LEU A 1 305 ? -66.73350 -139.81285 3.09063   1.000 51.36668  ? 304 LEU A CG  1 
ATOM   2124 C CD1 . LEU A 1 305 ? -66.71853 -138.97463 1.81548   1.000 43.12642  ? 304 LEU A CD1 1 
ATOM   2125 C CD2 . LEU A 1 305 ? -66.12403 -139.04072 4.25134   1.000 46.30276  ? 304 LEU A CD2 1 
ATOM   2126 N N   . HIS A 1 306 ? -70.13396 -142.69397 4.46825   1.000 63.30544  ? 305 HIS A N   1 
ATOM   2127 C CA  . HIS A 1 306 ? -71.52439 -143.11925 4.59872   1.000 69.28707  ? 305 HIS A CA  1 
ATOM   2128 C C   . HIS A 1 306 ? -71.80045 -143.66337 5.99510   1.000 70.63887  ? 305 HIS A C   1 
ATOM   2129 O O   . HIS A 1 306 ? -72.37462 -142.97186 6.83593   1.000 82.00624  ? 305 HIS A O   1 
ATOM   2130 C CB  . HIS A 1 306 ? -71.87243 -144.17359 3.54498   1.000 73.33182  ? 305 HIS A CB  1 
ATOM   2131 C CG  . HIS A 1 306 ? -71.90598 -143.64354 2.14474   1.000 72.02962  ? 305 HIS A CG  1 
ATOM   2132 N ND1 . HIS A 1 306 ? -72.04181 -144.46115 1.04325   1.000 74.46796  ? 305 HIS A ND1 1 
ATOM   2133 C CD2 . HIS A 1 306 ? -71.82262 -142.37928 1.66619   1.000 66.50945  ? 305 HIS A CD2 1 
ATOM   2134 C CE1 . HIS A 1 306 ? -72.03990 -143.72405 -0.05313  1.000 69.66289  ? 305 HIS A CE1 1 
ATOM   2135 N NE2 . HIS A 1 306 ? -71.90878 -142.45720 0.29710   1.000 64.68131  ? 305 HIS A NE2 1 
ATOM   2136 N N   . ARG B 2 2   ? -55.77869 -127.94584 22.26356  1.000 78.38567  ? 2   ARG B N   1 
ATOM   2137 C CA  . ARG B 2 2   ? -55.08301 -126.96434 21.43853  1.000 80.81957  ? 2   ARG B CA  1 
ATOM   2138 C C   . ARG B 2 2   ? -56.06034 -126.29677 20.47200  1.000 78.27540  ? 2   ARG B C   1 
ATOM   2139 O O   . ARG B 2 2   ? -56.90036 -126.96422 19.86472  1.000 79.56764  ? 2   ARG B O   1 
ATOM   2140 C CB  . ARG B 2 2   ? -53.93311 -127.62608 20.67423  1.000 79.46777  ? 2   ARG B CB  1 
ATOM   2141 C CG  . ARG B 2 2   ? -52.94680 -126.65061 20.04909  1.000 75.04661  ? 2   ARG B CG  1 
ATOM   2142 C CD  . ARG B 2 2   ? -51.73907 -127.37513 19.45980  1.000 70.69458  ? 2   ARG B CD  1 
ATOM   2143 N NE  . ARG B 2 2   ? -50.96854 -128.08937 20.47273  1.000 68.01641  ? 2   ARG B NE  1 
ATOM   2144 C CZ  . ARG B 2 2   ? -51.04760 -129.39505 20.69759  1.000 65.59034  ? 2   ARG B CZ  1 
ATOM   2145 N NH1 . ARG B 2 2   ? -51.84763 -130.17364 19.98517  1.000 59.42604  ? 2   ARG B NH1 1 
ATOM   2146 N NH2 . ARG B 2 2   ? -50.30596 -129.93338 21.66193  1.000 57.60636  ? 2   ARG B NH2 1 
ATOM   2147 N N   . LYS B 2 3   ? -55.94103 -124.97846 20.32428  1.000 71.07061  ? 3   LYS B N   1 
ATOM   2148 C CA  . LYS B 2 3   ? -56.92172 -124.19762 19.57639  1.000 66.06742  ? 3   LYS B CA  1 
ATOM   2149 C C   . LYS B 2 3   ? -56.65536 -124.32270 18.08053  1.000 60.77253  ? 3   LYS B C   1 
ATOM   2150 O O   . LYS B 2 3   ? -55.63210 -123.84826 17.57676  1.000 63.04875  ? 3   LYS B O   1 
ATOM   2151 C CB  . LYS B 2 3   ? -56.88953 -122.73650 20.01161  1.000 66.38923  ? 3   LYS B CB  1 
ATOM   2152 C CG  . LYS B 2 3   ? -58.02370 -121.90300 19.43632  1.000 65.73317  ? 3   LYS B CG  1 
ATOM   2153 N N   . ARG B 2 4   ? -57.58283 -124.95122 17.37041  1.000 53.53734  ? 4   ARG B N   1 
ATOM   2154 C CA  . ARG B 2 4   ? -57.56122 -125.01622 15.91596  1.000 52.06331  ? 4   ARG B CA  1 
ATOM   2155 C C   . ARG B 2 4   ? -58.44679 -123.90741 15.36367  1.000 47.51164  ? 4   ARG B C   1 
ATOM   2156 O O   . ARG B 2 4   ? -59.57296 -123.71740 15.83390  1.000 49.20607  ? 4   ARG B O   1 
ATOM   2157 C CB  . ARG B 2 4   ? -58.04272 -126.38488 15.43663  1.000 50.65772  ? 4   ARG B CB  1 
ATOM   2158 C CG  . ARG B 2 4   ? -58.34822 -126.47684 13.95640  1.000 42.16742  ? 4   ARG B CG  1 
ATOM   2159 C CD  . ARG B 2 4   ? -58.77517 -127.89056 13.61080  1.000 41.76102  ? 4   ARG B CD  1 
ATOM   2160 N NE  . ARG B 2 4   ? -59.35348 -127.98348 12.27633  1.000 41.21684  ? 4   ARG B NE  1 
ATOM   2161 C CZ  . ARG B 2 4   ? -58.64787 -128.11556 11.16288  1.000 40.63698  ? 4   ARG B CZ  1 
ATOM   2162 N NH1 . ARG B 2 4   ? -57.32549 -128.14447 11.18307  1.000 41.07810  ? 4   ARG B NH1 1 
ATOM   2163 N NH2 . ARG B 2 4   ? -59.28546 -128.22318 9.99992   1.000 38.48262  ? 4   ARG B NH2 1 
ATOM   2164 N N   . ARG B 2 5   ? -57.93912 -123.17117 14.37812  1.000 45.15141  ? 5   ARG B N   1 
ATOM   2165 C CA  . ARG B 2 5   ? -58.65535 -122.01278 13.86981  1.000 46.66392  ? 5   ARG B CA  1 
ATOM   2166 C C   . ARG B 2 5   ? -58.46575 -121.89059 12.36476  1.000 45.20574  ? 5   ARG B C   1 
ATOM   2167 O O   . ARG B 2 5   ? -57.50473 -122.40496 11.78835  1.000 44.95291  ? 5   ARG B O   1 
ATOM   2168 C CB  . ARG B 2 5   ? -58.19340 -120.72126 14.56152  1.000 51.57386  ? 5   ARG B CB  1 
ATOM   2169 C CG  . ARG B 2 5   ? -56.79916 -120.25068 14.15817  1.000 54.51244  ? 5   ARG B CG  1 
ATOM   2170 C CD  . ARG B 2 5   ? -56.42001 -118.97189 14.89511  1.000 60.88226  ? 5   ARG B CD  1 
ATOM   2171 N NE  . ARG B 2 5   ? -55.42470 -118.19037 14.16976  1.000 64.97177  ? 5   ARG B NE  1 
ATOM   2172 C CZ  . ARG B 2 5   ? -55.71445 -117.29767 13.23123  1.000 65.43711  ? 5   ARG B CZ  1 
ATOM   2173 N NH1 . ARG B 2 5   ? -56.96440 -117.05610 12.86732  1.000 64.62178  ? 5   ARG B NH1 1 
ATOM   2174 N NH2 . ARG B 2 5   ? -54.72615 -116.62871 12.64357  1.000 65.82273  ? 5   ARG B NH2 1 
ATOM   2175 N N   . ARG B 2 6   ? -59.41153 -121.20163 11.73553  1.000 46.05865  ? 6   ARG B N   1 
ATOM   2176 C CA  . ARG B 2 6   ? -59.27883 -120.79488 10.34872  1.000 46.92541  ? 6   ARG B CA  1 
ATOM   2177 C C   . ARG B 2 6   ? -58.28934 -119.63862 10.23777  1.000 48.25189  ? 6   ARG B C   1 
ATOM   2178 O O   . ARG B 2 6   ? -57.98894 -118.94750 11.21390  1.000 44.99480  ? 6   ARG B O   1 
ATOM   2179 C CB  . ARG B 2 6   ? -60.63855 -120.37975 9.77718   1.000 48.91085  ? 6   ARG B CB  1 
ATOM   2180 C CG  . ARG B 2 6   ? -61.65748 -121.50761 9.68464   1.000 46.13828  ? 6   ARG B CG  1 
ATOM   2181 C CD  . ARG B 2 6   ? -63.01300 -120.99826 9.20461   1.000 47.59652  ? 6   ARG B CD  1 
ATOM   2182 N NE  . ARG B 2 6   ? -63.94852 -122.09159 8.96512   1.000 43.47291  ? 6   ARG B NE  1 
ATOM   2183 C CZ  . ARG B 2 6   ? -64.10199 -122.70359 7.79809   1.000 44.63994  ? 6   ARG B CZ  1 
ATOM   2184 N NH1 . ARG B 2 6   ? -63.40644 -122.34304 6.73107   1.000 42.81956  ? 6   ARG B NH1 1 
ATOM   2185 N NH2 . ARG B 2 6   ? -64.97388 -123.70371 7.69885   1.000 43.15718  ? 6   ARG B NH2 1 
ATOM   2186 N N   . HIS B 2 7   ? -57.78262 -119.43107 9.02882   1.000 42.75222  ? 7   HIS B N   1 
ATOM   2187 C CA  . HIS B 2 7   ? -56.84626 -118.34323 8.74905   1.000 48.77669  ? 7   HIS B CA  1 
ATOM   2188 C C   . HIS B 2 7   ? -57.30181 -117.61263 7.49446   1.000 50.08641  ? 7   HIS B C   1 
ATOM   2189 O O   . HIS B 2 7   ? -57.17431 -118.16594 6.38276   1.000 48.82474  ? 7   HIS B O   1 
ATOM   2190 C CB  . HIS B 2 7   ? -55.42257 -118.86863 8.58398   1.000 42.92351  ? 7   HIS B CB  1 
ATOM   2191 C CG  . HIS B 2 7   ? -54.92659 -119.65286 9.75888   1.000 45.22484  ? 7   HIS B CG  1 
ATOM   2192 N ND1 . HIS B 2 7   ? -55.23913 -120.98118 9.95234   1.000 42.70292  ? 7   HIS B ND1 1 
ATOM   2193 C CD2 . HIS B 2 7   ? -54.13772 -119.29649 10.80046  1.000 45.28495  ? 7   HIS B CD2 1 
ATOM   2194 C CE1 . HIS B 2 7   ? -54.66600 -121.40913 11.06341  1.000 45.15694  ? 7   HIS B CE1 1 
ATOM   2195 N NE2 . HIS B 2 7   ? -53.99082 -120.40680 11.59644  1.000 45.61993  ? 7   HIS B NE2 1 
ATOM   2196 N N   . PRO B 2 8   ? -57.82956 -116.39454 7.61462   1.000 53.00288  ? 8   PRO B N   1 
ATOM   2197 C CA  . PRO B 2 8   ? -58.29552 -115.67079 6.42588   1.000 56.18651  ? 8   PRO B CA  1 
ATOM   2198 C C   . PRO B 2 8   ? -57.17126 -115.44012 5.42665   1.000 60.23063  ? 8   PRO B C   1 
ATOM   2199 O O   . PRO B 2 8   ? -55.99562 -115.34204 5.78623   1.000 57.79320  ? 8   PRO B O   1 
ATOM   2200 C CB  . PRO B 2 8   ? -58.81523 -114.34579 6.99699   1.000 60.30929  ? 8   PRO B CB  1 
ATOM   2201 C CG  . PRO B 2 8   ? -59.13848 -114.64916 8.42705   1.000 59.69929  ? 8   PRO B CG  1 
ATOM   2202 C CD  . PRO B 2 8   ? -58.11439 -115.66128 8.85950   1.000 58.20335  ? 8   PRO B CD  1 
ATOM   2203 N N   . SER B 2 9   ? -57.55155 -115.35848 4.15436   1.000 62.33599  ? 9   SER B N   1 
ATOM   2204 C CA  . SER B 2 9   ? -56.59026 -115.16551 3.07857   1.000 59.18472  ? 9   SER B CA  1 
ATOM   2205 C C   . SER B 2 9   ? -56.23861 -113.69084 2.93140   1.000 67.12381  ? 9   SER B C   1 
ATOM   2206 O O   . SER B 2 9   ? -57.09839 -112.81571 3.06589   1.000 74.30042  ? 9   SER B O   1 
ATOM   2207 C CB  . SER B 2 9   ? -57.15329 -115.70330 1.76247   1.000 58.83623  ? 9   SER B CB  1 
ATOM   2208 O OG  . SER B 2 9   ? -57.54636 -117.06100 1.89274   1.000 56.20762  ? 9   SER B OG  1 
ATOM   2209 N N   . GLY B 2 10  ? -54.96647 -113.42087 2.65186   1.000 65.30963  ? 10  GLY B N   1 
ATOM   2210 C CA  . GLY B 2 10  ? -54.49259 -112.05888 2.48192   1.000 67.37296  ? 10  GLY B CA  1 
ATOM   2211 C C   . GLY B 2 10  ? -53.94345 -111.43829 3.75280   1.000 71.64064  ? 10  GLY B C   1 
ATOM   2212 O O   . GLY B 2 10  ? -53.06052 -112.00096 4.40204   1.000 71.59761  ? 10  GLY B O   1 
HETATM 2213 C C1  . GOL C 3 .   ? -45.46898 -128.16675 15.54237  0.749 48.98205  ? 401 GOL A C1  1 
HETATM 2214 O O1  . GOL C 3 .   ? -45.91079 -129.41663 15.10249  0.749 45.11526  ? 401 GOL A O1  1 
HETATM 2215 C C2  . GOL C 3 .   ? -43.97108 -128.05999 15.16107  0.749 53.80464  ? 401 GOL A C2  1 
HETATM 2216 O O2  . GOL C 3 .   ? -43.66552 -128.82225 14.04671  0.749 42.43125  ? 401 GOL A O2  1 
HETATM 2217 C C3  . GOL C 3 .   ? -43.71794 -126.55048 14.92811  0.749 50.24606  ? 401 GOL A C3  1 
HETATM 2218 O O3  . GOL C 3 .   ? -42.35530 -126.40622 14.67538  0.749 52.15723  ? 401 GOL A O3  1 
HETATM 2219 N N2  . XJL D 4 .   ? -70.68481 -124.02245 -2.52079  0.916 55.39404  ? 402 XJL A N2  1 
HETATM 2220 C C2  . XJL D 4 .   ? -67.32125 -120.68320 -2.52553  0.916 46.15458  ? 402 XJL A C2  1 
HETATM 2221 N N1  . XJL D 4 .   ? -66.79878 -121.68524 3.88656   0.916 55.35596  ? 402 XJL A N1  1 
HETATM 2222 C C4  . XJL D 4 .   ? -67.15315 -122.38617 -4.20314  0.916 44.09334  ? 402 XJL A C4  1 
HETATM 2223 C C5  . XJL D 4 .   ? -68.13680 -123.11866 -3.56186  0.916 43.09009  ? 402 XJL A C5  1 
HETATM 2224 C C14 . XJL D 4 .   ? -71.07573 -124.41792 -0.32681  0.916 53.52030  ? 402 XJL A C14 1 
HETATM 2225 C C7  . XJL D 4 .   ? -69.95831 -123.60815 -0.40906  0.916 47.25454  ? 402 XJL A C7  1 
HETATM 2226 C C10 . XJL D 4 .   ? -67.00778 -122.95722 1.84345   0.916 48.44983  ? 402 XJL A C10 1 
HETATM 2227 C C15 . XJL D 4 .   ? -71.46869 -124.63464 -1.64350  0.916 53.57235  ? 402 XJL A C15 1 
HETATM 2228 C C8  . XJL D 4 .   ? -69.12875 -123.08708 0.69867   0.916 53.01244  ? 402 XJL A C8  1 
HETATM 2229 C C11 . XJL D 4 .   ? -67.56374 -122.13914 2.83213   0.916 56.67863  ? 402 XJL A C11 1 
HETATM 2230 C C13 . XJL D 4 .   ? -69.68473 -122.26727 1.67677   0.916 56.18287  ? 402 XJL A C13 1 
HETATM 2231 C C1  . XJL D 4 .   ? -66.73119 -121.16100 -3.69294  0.916 42.89739  ? 402 XJL A C1  1 
HETATM 2232 C C9  . XJL D 4 .   ? -67.78137 -123.42372 0.79486   0.916 49.34371  ? 402 XJL A C9  1 
HETATM 2233 C C3  . XJL D 4 .   ? -68.30737 -121.41041 -1.88209  0.916 44.97065  ? 402 XJL A C3  1 
HETATM 2234 C C12 . XJL D 4 .   ? -68.91684 -121.80020 2.72974   0.916 58.32866  ? 402 XJL A C12 1 
HETATM 2235 C C6  . XJL D 4 .   ? -68.71927 -122.63361 -2.39734  0.916 43.96625  ? 402 XJL A C6  1 
HETATM 2236 O O1  . XJL D 4 .   ? -65.21036 -120.91754 -5.47996  0.916 40.99646  ? 402 XJL A O1  1 
HETATM 2237 N N   . XJL D 4 .   ? -69.74419 -123.38471 -1.74277  0.916 49.60128  ? 402 XJL A N   1 
HETATM 2238 C C   . XJL D 4 .   ? -65.66089 -120.38317 -4.37372  0.916 41.85775  ? 402 XJL A C   1 
HETATM 2239 O O   . XJL D 4 .   ? -65.24472 -119.32718 -3.91389  0.916 45.30487  ? 402 XJL A O   1 
HETATM 2240 O O   . HOH E 5 .   ? -44.05033 -141.75581 -13.36384 1.000 51.92976  ? 501 HOH A O   1 
HETATM 2241 O O   . HOH E 5 .   ? -39.39337 -147.21294 12.74585  1.000 45.09171  ? 502 HOH A O   1 
HETATM 2242 O O   . HOH E 5 .   ? -40.62266 -121.43514 -4.54077  1.000 37.70637  ? 503 HOH A O   1 
HETATM 2243 O O   . HOH E 5 .   ? -67.20993 -110.98980 2.79413   1.000 62.67005  ? 504 HOH A O   1 
HETATM 2244 O O   . HOH E 5 .   ? -48.85737 -130.41410 -18.56257 1.000 64.90115  ? 505 HOH A O   1 
HETATM 2245 O O   . HOH E 5 .   ? -46.94573 -127.31482 -13.59779 1.000 56.59141  ? 506 HOH A O   1 
HETATM 2246 O O   . HOH E 5 .   ? -43.38815 -147.30150 14.00885  1.000 44.22574  ? 507 HOH A O   1 
HETATM 2247 O O   . HOH E 5 .   ? -69.32502 -109.98615 0.83954   1.000 52.69840  ? 508 HOH A O   1 
HETATM 2248 O O   . HOH E 5 .   ? -60.78567 -118.20648 6.73033   1.000 50.61540  ? 509 HOH A O   1 
HETATM 2249 O O   . HOH E 5 .   ? -59.34846 -138.79773 14.71449  1.000 46.66929  ? 510 HOH A O   1 
HETATM 2250 O O   . HOH E 5 .   ? -48.85502 -124.44041 9.03787   1.000 33.25250  ? 511 HOH A O   1 
HETATM 2251 O O   . HOH E 5 .   ? -62.13389 -112.33991 -7.27261  1.000 51.80522  ? 512 HOH A O   1 
HETATM 2252 O O   . HOH E 5 .   ? -74.27406 -108.46778 -6.25752  1.000 45.53085  ? 513 HOH A O   1 
HETATM 2253 O O   . HOH E 5 .   ? -54.99502 -123.84245 13.74000  1.000 43.49161  ? 514 HOH A O   1 
HETATM 2254 O O   . HOH E 5 .   ? -58.81937 -131.57646 14.22069  1.000 39.84678  ? 515 HOH A O   1 
HETATM 2255 O O   . HOH E 5 .   ? -55.59584 -146.86591 0.34592   1.000 44.74713  ? 516 HOH A O   1 
HETATM 2256 O O   . HOH E 5 .   ? -39.58707 -127.82176 7.05473   1.000 49.54236  ? 517 HOH A O   1 
HETATM 2257 O O   . HOH E 5 .   ? -59.82779 -117.91803 3.84146   1.000 53.58845  ? 518 HOH A O   1 
HETATM 2258 O O   . HOH E 5 .   ? -56.58213 -122.32647 7.79644   1.000 37.78965  ? 519 HOH A O   1 
HETATM 2259 O O   . HOH E 5 .   ? -42.96045 -119.84022 -11.18312 1.000 42.66275  ? 520 HOH A O   1 
HETATM 2260 O O   . HOH E 5 .   ? -41.37031 -140.73872 -5.45983  1.000 45.96396  ? 521 HOH A O   1 
HETATM 2261 O O   . HOH E 5 .   ? -52.14636 -144.88576 -5.83214  1.000 44.70551  ? 522 HOH A O   1 
HETATM 2262 O O   . HOH E 5 .   ? -53.43378 -121.71104 1.49133   1.000 36.91698  ? 523 HOH A O   1 
HETATM 2263 O O   . HOH E 5 .   ? -54.32562 -127.84224 17.16203  1.000 55.09678  ? 524 HOH A O   1 
HETATM 2264 O O   . HOH E 5 .   ? -61.92550 -134.97053 -6.91104  1.000 39.93768  ? 525 HOH A O   1 
HETATM 2265 O O   . HOH E 5 .   ? -59.84158 -141.24658 -4.06579  1.000 39.62706  ? 526 HOH A O   1 
HETATM 2266 O O   . HOH E 5 .   ? -40.51238 -135.70020 -11.64582 1.000 47.87239  ? 527 HOH A O   1 
HETATM 2267 O O   . HOH E 5 .   ? -64.51874 -123.58742 -13.38042 1.000 46.81886  ? 528 HOH A O   1 
HETATM 2268 O O   . HOH E 5 .   ? -64.32575 -123.05812 4.11007   1.000 41.42795  ? 529 HOH A O   1 
HETATM 2269 O O   . HOH E 5 .   ? -59.97414 -150.83606 3.22982   1.000 63.95214  ? 530 HOH A O   1 
HETATM 2270 O O   . HOH E 5 .   ? -50.27005 -147.72715 0.44848   1.000 56.61386  ? 531 HOH A O   1 
HETATM 2271 O O   . HOH E 5 .   ? -48.68916 -145.85700 11.80989  1.000 48.99047  ? 532 HOH A O   1 
HETATM 2272 O O   . HOH E 5 .   ? -64.89907 -126.29713 12.35789  1.000 49.26526  ? 533 HOH A O   1 
HETATM 2273 O O   . HOH E 5 .   ? -63.41494 -119.52865 -7.10168  1.000 36.98653  ? 534 HOH A O   1 
HETATM 2274 O O   . HOH E 5 .   ? -45.79014 -140.04941 14.47535  1.000 34.30212  ? 535 HOH A O   1 
HETATM 2275 O O   . HOH E 5 .   ? -57.09446 -118.87863 -4.87846  1.000 39.12439  ? 536 HOH A O   1 
HETATM 2276 O O   . HOH E 5 .   ? -39.04543 -128.59622 -6.41569  1.000 47.78082  ? 537 HOH A O   1 
HETATM 2277 O O   . HOH E 5 .   ? -52.88952 -115.38085 5.97903   1.000 53.59114  ? 538 HOH A O   1 
HETATM 2278 O O   . HOH E 5 .   ? -46.27282 -122.61210 5.96007   1.000 34.09227  ? 539 HOH A O   1 
HETATM 2279 O O   . HOH E 5 .   ? -43.44613 -118.22228 -17.70129 1.000 45.57275  ? 540 HOH A O   1 
HETATM 2280 O O   . HOH E 5 .   ? -56.36499 -131.62165 -17.07119 1.000 53.86992  ? 541 HOH A O   1 
HETATM 2281 O O   . HOH E 5 .   ? -72.35509 -129.35219 -11.95535 1.000 74.81886  ? 542 HOH A O   1 
HETATM 2282 O O   . HOH E 5 .   ? -40.23387 -125.46833 8.67476   1.000 49.24904  ? 543 HOH A O   1 
HETATM 2283 O O   . HOH E 5 .   ? -43.11740 -123.01279 -11.14744 1.000 44.62165  ? 544 HOH A O   1 
HETATM 2284 O O   . HOH E 5 .   ? -51.79147 -124.54929 -7.66653  1.000 35.09221  ? 545 HOH A O   1 
HETATM 2285 O O   . HOH E 5 .   ? -38.26315 -120.37132 -5.47937  1.000 46.16689  ? 546 HOH A O   1 
HETATM 2286 O O   . HOH E 5 .   ? -45.26974 -111.71933 -9.33145  1.000 60.18626  ? 547 HOH A O   1 
HETATM 2287 O O   . HOH E 5 .   ? -37.24718 -133.22644 -6.57270  1.000 58.01500  ? 548 HOH A O   1 
HETATM 2288 O O   . HOH E 5 .   ? -34.12186 -128.38030 1.82200   1.000 50.94545  ? 549 HOH A O   1 
HETATM 2289 O O   . HOH E 5 .   ? -60.16854 -115.79447 -0.23698  1.000 62.56765  ? 550 HOH A O   1 
HETATM 2290 O O   . HOH E 5 .   ? -59.56885 -134.78546 -8.16904  1.000 37.81521  ? 551 HOH A O   1 
HETATM 2291 O O   . HOH E 5 .   ? -51.04102 -143.84689 11.50831  1.000 53.86508  ? 552 HOH A O   1 
HETATM 2292 O O   . HOH E 5 .   ? -54.36889 -132.17797 16.57926  1.000 53.52376  ? 553 HOH A O   1 
HETATM 2293 O O   . HOH E 5 .   ? -65.27552 -144.10090 -7.54630  1.000 46.15491  ? 554 HOH A O   1 
HETATM 2294 O O   . HOH E 5 .   ? -58.59382 -117.34305 -1.84756  1.000 51.45790  ? 555 HOH A O   1 
HETATM 2295 O O   . HOH E 5 .   ? -56.11859 -125.00545 8.16327   1.000 34.61622  ? 556 HOH A O   1 
HETATM 2296 O O   . HOH E 5 .   ? -45.94957 -115.14531 12.62141  1.000 58.34807  ? 557 HOH A O   1 
HETATM 2297 O O   . HOH E 5 .   ? -56.63814 -144.60608 0.06962   1.000 39.75117  ? 558 HOH A O   1 
HETATM 2298 O O   . HOH E 5 .   ? -41.73890 -128.86539 -6.22286  1.000 41.69924  ? 559 HOH A O   1 
HETATM 2299 O O   . HOH E 5 .   ? -50.80240 -123.05320 -5.44820  1.000 38.52423  ? 560 HOH A O   1 
HETATM 2300 O O   . HOH E 5 .   ? -57.03743 -136.04835 16.47258  1.000 49.08260  ? 561 HOH A O   1 
HETATM 2301 O O   . HOH E 5 .   ? -62.71512 -142.37688 8.84967   1.000 50.18689  ? 562 HOH A O   1 
HETATM 2302 O O   . HOH E 5 .   ? -60.68586 -115.02165 -2.52730  1.000 61.28790  ? 563 HOH A O   1 
HETATM 2303 O O   . HOH E 5 .   ? -55.58671 -148.22660 -6.41028  1.000 55.72030  ? 564 HOH A O   1 
HETATM 2304 O O   . HOH E 5 .   ? -65.92257 -103.29640 -14.53552 1.000 71.72574  ? 565 HOH A O   1 
HETATM 2305 O O   . HOH E 5 .   ? -69.71243 -128.18867 8.90218   1.000 55.99391  ? 566 HOH A O   1 
HETATM 2306 O O   . HOH E 5 .   ? -62.97261 -114.30513 -4.13667  1.000 60.13781  ? 567 HOH A O   1 
HETATM 2307 O O   . HOH E 5 .   ? -58.061   -138.565   -11.462   1.000 45.25602  ? 568 HOH A O   1 
HETATM 2308 O O   . HOH E 5 .   ? -51.30921 -123.11901 -2.59426  1.000 36.64539  ? 569 HOH A O   1 
HETATM 2309 O O   . HOH E 5 .   ? -38.18946 -132.33576 10.88776  1.000 57.24502  ? 570 HOH A O   1 
HETATM 2310 O O   . HOH E 5 .   ? -55.45158 -146.27934 7.45595   1.000 46.03343  ? 571 HOH A O   1 
HETATM 2311 O O   . HOH E 5 .   ? -43.596   -124.527   -19.211   1.000 63.00236  ? 572 HOH A O   1 
HETATM 2312 O O   . HOH E 5 .   ? -34.15825 -123.85597 -4.83736  1.000 57.32273  ? 573 HOH A O   1 
HETATM 2313 O O   . HOH E 5 .   ? -48.15766 -117.03657 -18.00086 1.000 58.03582  ? 574 HOH A O   1 
HETATM 2314 O O   . HOH E 5 .   ? -52.03665 -113.66534 -13.19630 1.000 49.71016  ? 575 HOH A O   1 
HETATM 2315 O O   . HOH E 5 .   ? -41.04036 -124.30624 -8.80088  1.000 44.65453  ? 576 HOH A O   1 
HETATM 2316 O O   . HOH E 5 .   ? -51.63932 -120.10748 0.63612   1.000 43.23268  ? 577 HOH A O   1 
HETATM 2317 O O   . HOH E 5 .   ? -48.48337 -113.22898 3.46188   1.000 46.63287  ? 578 HOH A O   1 
HETATM 2318 O O   . HOH E 5 .   ? -52.35650 -117.40683 7.89135   1.000 41.25331  ? 579 HOH A O   1 
HETATM 2319 O O   . HOH E 5 .   ? -53.83479 -144.20342 10.28764  1.000 42.81328  ? 580 HOH A O   1 
HETATM 2320 O O   . HOH E 5 .   ? -60.17834 -111.75586 -8.95994  1.000 50.70295  ? 581 HOH A O   1 
HETATM 2321 O O   . HOH E 5 .   ? -38.99820 -138.56131 7.98755   1.000 53.84152  ? 582 HOH A O   1 
HETATM 2322 O O   . HOH E 5 .   ? -60.67932 -141.11254 9.74080   1.000 42.97142  ? 583 HOH A O   1 
HETATM 2323 O O   . HOH E 5 .   ? -47.73131 -123.42323 17.39186  1.000 61.68040  ? 584 HOH A O   1 
HETATM 2324 O O   . HOH E 5 .   ? -71.79054 -113.46502 -19.30013 1.000 63.96203  ? 585 HOH A O   1 
HETATM 2325 O O   . HOH E 5 .   ? -73.76635 -104.14510 -7.51593  1.000 62.07044  ? 586 HOH A O   1 
HETATM 2326 O O   . HOH E 5 .   ? -48.49229 -121.59804 -5.61316  1.000 37.22412  ? 587 HOH A O   1 
HETATM 2327 O O   . HOH E 5 .   ? -44.74913 -133.36464 -11.99107 1.000 40.67225  ? 588 HOH A O   1 
HETATM 2328 O O   . HOH E 5 .   ? -37.96945 -136.58469 3.65260   1.000 51.92113  ? 589 HOH A O   1 
HETATM 2329 O O   . HOH E 5 .   ? -74.71051 -129.35769 2.12372   1.000 61.55358  ? 590 HOH A O   1 
HETATM 2330 O O   . HOH E 5 .   ? -44.38136 -130.82076 -10.84266 1.000 45.34888  ? 591 HOH A O   1 
HETATM 2331 O O   . HOH E 5 .   ? -49.71237 -121.10636 -1.43394  1.000 45.16078  ? 592 HOH A O   1 
HETATM 2332 O O   . HOH E 5 .   ? -43.40611 -115.54713 -17.58569 1.000 57.40997  ? 593 HOH A O   1 
HETATM 2333 O O   . HOH E 5 .   ? -67.69795 -109.21980 -1.41085  1.000 54.03324  ? 594 HOH A O   1 
HETATM 2334 O O   . HOH E 5 .   ? -39.164   -132.989   16.072    1.000 52.70327  ? 595 HOH A O   1 
HETATM 2335 O O   . HOH E 5 .   ? -48.58555 -120.02855 -3.46590  1.000 45.86526  ? 596 HOH A O   1 
HETATM 2336 O O   . HOH E 5 .   ? -73.574   -115.183   8.150     1.000 56.75233  ? 597 HOH A O   1 
HETATM 2337 O O   . HOH E 5 .   ? -59.49334 -137.45129 -9.30572  1.000 47.70136  ? 598 HOH A O   1 
HETATM 2338 O O   . HOH F 5 .   ? -55.98910 -124.60563 10.76375  1.000 40.57778  ? 101 HOH B O   1 
HETATM 2339 O O   . HOH F 5 .   ? -65.76174 -123.07433 11.08435  1.000 56.85332  ? 102 HOH B O   1 
HETATM 2340 O O   . HOH F 5 .   ? -61.89533 -120.40637 13.40099  1.000 46.71427  ? 103 HOH B O   1 
HETATM 2341 O O   . HOH F 5 .   ? -52.11419 -116.38578 10.56448  1.000 49.01403  ? 104 HOH B O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . PRO A 34  ? 1.13450 1.51505 1.54536 0.24030  -0.10176 -0.04398 33  PRO A N   
2    C CA  . PRO A 34  ? 1.10569 1.47276 1.52529 0.24228  -0.08459 -0.05373 33  PRO A CA  
3    C C   . PRO A 34  ? 1.03040 1.40522 1.43324 0.23709  -0.07687 -0.05225 33  PRO A C   
4    O O   . PRO A 34  ? 0.99665 1.38554 1.41516 0.24474  -0.07513 -0.05132 33  PRO A O   
5    C CB  . PRO A 34  ? 1.10721 1.48006 1.56501 0.25734  -0.08488 -0.05698 33  PRO A CB  
6    C CG  . PRO A 34  ? 1.08869 1.48481 1.55363 0.26265  -0.10145 -0.04705 33  PRO A CG  
7    C CD  . PRO A 34  ? 1.12195 1.51738 1.56163 0.25292  -0.11232 -0.04058 33  PRO A CD  
8    N N   . LEU A 35  ? 1.02040 1.38588 1.39140 0.22413  -0.07235 -0.05204 34  LEU A N   
9    C CA  . LEU A 35  ? 0.96308 1.33444 1.31588 0.21835  -0.06481 -0.05077 34  LEU A CA  
10   C C   . LEU A 35  ? 0.96381 1.32033 1.32520 0.22047  -0.04670 -0.06095 34  LEU A C   
11   O O   . LEU A 35  ? 0.89023 1.25489 1.24907 0.22094  -0.04002 -0.06067 34  LEU A O   
12   C CB  . LEU A 35  ? 0.92548 1.29258 1.24053 0.20357  -0.06707 -0.04660 34  LEU A CB  
13   N N   . GLU A 36  ? 1.00763 1.34240 1.37919 0.22179  -0.03850 -0.06994 35  GLU A N   
14   C CA  . GLU A 36  ? 0.97979 1.29915 1.35938 0.22355  -0.02084 -0.07995 35  GLU A CA  
15   C C   . GLU A 36  ? 0.96807 1.29716 1.38187 0.23740  -0.01766 -0.08271 35  GLU A C   
16   O O   . GLU A 36  ? 0.97138 1.29639 1.39014 0.23924  -0.00439 -0.08824 35  GLU A O   
17   C CB  . GLU A 36  ? 1.00231 1.29526 1.38216 0.22057  -0.01317 -0.08864 35  GLU A CB  
18   N N   . SER A 37  ? 0.94502 1.28685 1.38238 0.24716  -0.02957 -0.07896 36  SER A N   
19   C CA  . SER A 37  ? 0.92423 1.27534 1.39568 0.26079  -0.02770 -0.08152 36  SER A CA  
20   C C   . SER A 37  ? 0.86845 1.24546 1.34240 0.26481  -0.03446 -0.07351 36  SER A C   
21   O O   . SER A 37  ? 0.89371 1.27882 1.39283 0.27506  -0.03069 -0.07585 36  SER A O   
22   C CB  . SER A 37  ? 0.93196 1.28173 1.42990 0.27005  -0.03648 -0.08252 36  SER A CB  
23   N N   . GLN A 38  ? 0.86193 1.25206 1.31078 0.25704  -0.04422 -0.06423 37  GLN A N   
24   C CA  . GLN A 38  ? 0.77238 1.18781 1.22284 0.26063  -0.05190 -0.05591 37  GLN A CA  
25   C C   . GLN A 38  ? 0.72711 1.14625 1.15899 0.25473  -0.04228 -0.05553 37  GLN A C   
26   O O   . GLN A 38  ? 0.69962 1.13775 1.13869 0.25978  -0.04464 -0.05100 37  GLN A O   
27   C CB  . GLN A 38  ? 0.76386 1.19379 1.19990 0.25660  -0.06944 -0.04522 37  GLN A CB  
28   C CG  . GLN A 38  ? 0.74878 1.19946 1.19048 0.25963  -0.07893 -0.03497 37  GLN A CG  
29   C CD  . GLN A 38  ? 0.75603 1.21102 1.18226 0.25199  -0.09444 -0.02358 37  GLN A CD  
30   O OE1 . GLN A 38  ? 0.75836 1.21438 1.17314 0.24309  -0.09955 -0.01222 37  GLN A OE1 
31   N NE2 . GLN A 38  ? 0.73894 1.19396 1.16497 0.25483  -0.10168 -0.02737 37  GLN A NE2 
32   N N   . TYR A 39  ? 0.76008 1.16150 1.16845 0.24436  -0.03148 -0.06020 38  TYR A N   
33   C CA  . TYR A 39  ? 0.70518 1.10846 1.09367 0.23797  -0.02211 -0.06002 38  TYR A CA  
34   C C   . TYR A 39  ? 0.72495 1.10459 1.11164 0.23520  -0.00390 -0.07097 38  TYR A C   
35   O O   . TYR A 39  ? 0.75591 1.11551 1.14168 0.23234  0.00014  -0.07701 38  TYR A O   
36   C CB  . TYR A 39  ? 0.66195 1.07050 1.01428 0.22517  -0.02934 -0.05215 38  TYR A CB  
37   C CG  . TYR A 39  ? 0.63787 1.06979 0.98940 0.22692  -0.04710 -0.04097 38  TYR A CG  
38   C CD1 . TYR A 39  ? 0.58371 1.03777 0.93573 0.22990  -0.05113 -0.03425 38  TYR A CD1 
39   C CD2 . TYR A 39  ? 0.66770 1.09938 1.01798 0.22563  -0.05971 -0.03713 38  TYR A CD2 
40   C CE1 . TYR A 39  ? 0.58792 1.06327 0.93935 0.23154  -0.06718 -0.02403 38  TYR A CE1 
41   C CE2 . TYR A 39  ? 0.63429 1.08706 0.98382 0.22724  -0.07577 -0.02692 38  TYR A CE2 
42   C CZ  . TYR A 39  ? 0.60971 1.08428 0.95987 0.23019  -0.07941 -0.02041 38  TYR A CZ  
43   O OH  . TYR A 39  ? 0.62157 1.11703 0.97103 0.23181  -0.09522 -0.01026 38  TYR A OH  
44   N N   . GLN A 40  ? 0.69523 1.07728 1.08138 0.23610  0.00719  -0.07346 39  GLN A N   
45   C CA  . GLN A 40  ? 0.66656 1.02748 1.04788 0.23268  0.02523  -0.08326 39  GLN A CA  
46   C C   . GLN A 40  ? 0.66793 1.02454 1.01119 0.21902  0.02903  -0.08073 39  GLN A C   
47   O O   . GLN A 40  ? 0.67206 1.04440 1.00323 0.21693  0.02697  -0.07470 39  GLN A O   
48   C CB  . GLN A 40  ? 0.65640 1.02167 1.06204 0.24258  0.03570  -0.08809 39  GLN A CB  
49   C CG  . GLN A 40  ? 0.65165 0.99483 1.05569 0.24027  0.05489  -0.09874 39  GLN A CG  
50   N N   . VAL A 41  ? 0.66598 1.00139 0.99034 0.20975  0.03433  -0.08526 40  VAL A N   
51   C CA  . VAL A 41  ? 0.67185 1.00188 0.95875 0.19606  0.03674  -0.08277 40  VAL A CA  
52   C C   . VAL A 41  ? 0.66130 0.97997 0.94093 0.19359  0.05435  -0.08960 40  VAL A C   
53   O O   . VAL A 41  ? 0.70017 1.00012 0.99223 0.19637  0.06733  -0.09934 40  VAL A O   
54   C CB  . VAL A 41  ? 0.63827 0.95066 0.90723 0.18688  0.03418  -0.08437 40  VAL A CB  
55   C CG1 . VAL A 41  ? 0.62931 0.93658 0.85922 0.17258  0.03621  -0.08163 40  VAL A CG1 
56   C CG2 . VAL A 41  ? 0.61937 0.94275 0.89669 0.18983  0.01692  -0.07776 40  VAL A CG2 
57   N N   . GLY A 42  ? 0.64780 0.97758 0.90708 0.18831  0.05488  -0.08448 41  GLY A N   
58   C CA  . GLY A 42  ? 0.64072 0.96104 0.89003 0.18524  0.07077  -0.08995 41  GLY A CA  
59   C C   . GLY A 42  ? 0.67086 0.97626 0.88297 0.17078  0.07578  -0.09068 41  GLY A C   
60   O O   . GLY A 42  ? 0.68242 0.97484 0.88193 0.16399  0.07257  -0.09169 41  GLY A O   
61   N N   . PRO A 43  ? 0.68270 0.98963 0.87633 0.16579  0.08369  -0.09018 42  PRO A N   
62   C CA  . PRO A 43  ? 0.68036 0.97228 0.83823 0.15205  0.08962  -0.09140 42  PRO A CA  
63   C C   . PRO A 43  ? 0.64554 0.94898 0.77693 0.14281  0.07486  -0.08153 42  PRO A C   
64   O O   . PRO A 43  ? 0.60972 0.93549 0.74739 0.14659  0.06093  -0.07282 42  PRO A O   
65   C CB  . PRO A 43  ? 0.65424 0.94706 0.80456 0.15150  0.10200  -0.09343 42  PRO A CB  
66   C CG  . PRO A 43  ? 0.71862 1.03644 0.89054 0.16192  0.09522  -0.08772 42  PRO A CG  
67   C CD  . PRO A 43  ? 0.69452 1.01652 0.89943 0.17266  0.08796  -0.08869 42  PRO A CD  
68   N N   . LEU A 44  ? 0.64691 0.93431 0.74811 0.13040  0.07835  -0.08312 43  LEU A N   
69   C CA  . LEU A 44  ? 0.65025 0.94604 0.72306 0.12014  0.06588  -0.07449 43  LEU A CA  
70   C C   . LEU A 44  ? 0.66999 0.98308 0.72613 0.11706  0.06409  -0.06763 43  LEU A C   
71   O O   . LEU A 44  ? 0.72079 1.02579 0.76425 0.11350  0.07654  -0.07149 43  LEU A O   
72   C CB  . LEU A 44  ? 0.68056 0.95295 0.72641 0.10784  0.07126  -0.07893 43  LEU A CB  
73   C CG  . LEU A 44  ? 0.68803 0.96534 0.70297 0.09605  0.05934  -0.07112 43  LEU A CG  
74   C CD1 . LEU A 44  ? 0.67291 0.96157 0.69967 0.09930  0.04295  -0.06517 43  LEU A CD1 
75   C CD2 . LEU A 44  ? 0.71995 0.97225 0.70788 0.08401  0.06798  -0.07688 43  LEU A CD2 
76   N N   . LEU A 45  ? 0.63131 0.96810 0.68750 0.11852  0.04869  -0.05743 44  LEU A N   
77   C CA  . LEU A 45  ? 0.63558 0.99024 0.67651 0.11584  0.04580  -0.05024 44  LEU A CA  
78   C C   . LEU A 45  ? 0.67514 1.02585 0.67728 0.10134  0.04295  -0.04620 44  LEU A C   
79   O O   . LEU A 45  ? 0.72096 1.07572 0.70448 0.09654  0.04752  -0.04421 44  LEU A O   
80   C CB  . LEU A 45  ? 0.62807 1.01034 0.68578 0.12374  0.03076  -0.04094 44  LEU A CB  
81   C CG  . LEU A 45  ? 0.58720 0.97768 0.68279 0.13856  0.03282  -0.04363 44  LEU A CG  
82   C CD1 . LEU A 45  ? 0.58154 0.99967 0.68964 0.14506  0.01738  -0.03368 44  LEU A CD1 
83   C CD2 . LEU A 45  ? 0.65742 1.04314 0.75852 0.14220  0.04844  -0.04956 44  LEU A CD2 
84   N N   . GLY A 46  ? 0.75812 1.10108 0.74777 0.09430  0.03545  -0.04494 45  GLY A N   
85   C CA  . GLY A 46  ? 0.71079 1.04954 0.66404 0.08037  0.03222  -0.04123 45  GLY A CA  
86   C C   . GLY A 46  ? 0.76417 1.09681 0.71063 0.07502  0.02216  -0.03949 45  GLY A C   
87   O O   . GLY A 46  ? 0.65627 0.99141 0.62594 0.08238  0.01568  -0.03962 45  GLY A O   
88   N N   . SER A 47  ? 0.76302 1.08727 0.67675 0.06189  0.02095  -0.03787 46  SER A N   
89   C CA  . SER A 47  ? 0.78584 1.10344 0.68872 0.05510  0.01172  -0.03603 46  SER A CA  
90   C C   . SER A 47  ? 0.85427 1.17632 0.72149 0.04195  0.00511  -0.02939 46  SER A C   
91   O O   . SER A 47  ? 0.89562 1.22053 0.74485 0.03722  0.01026  -0.02813 46  SER A O   
92   C CB  . SER A 47  ? 0.78340 1.07290 0.68788 0.05292  0.02243  -0.04636 46  SER A CB  
93   O OG  . SER A 47  ? 0.85529 1.12692 0.73706 0.04456  0.03603  -0.05221 46  SER A OG  
94   N N   . GLY A 48  ? 0.87865 1.20106 0.73589 0.03611  -0.00634 -0.02522 47  GLY A N   
95   C CA  . GLY A 48  ? 0.96760 1.29383 0.79185 0.02343  -0.01377 -0.01887 47  GLY A CA  
96   C C   . GLY A 48  ? 0.97268 1.31274 0.79834 0.02261  -0.03124 -0.01067 47  GLY A C   
97   O O   . GLY A 48  ? 0.94748 1.28229 0.79083 0.02738  -0.03489 -0.01280 47  GLY A O   
98   N N   . GLY A 49  ? 1.00569 1.36333 0.81254 0.01657  -0.04176 -0.00132 48  GLY A N   
99   C CA  . GLY A 49  ? 1.04169 1.41412 0.84869 0.01551  -0.05862 0.00718  48  GLY A CA  
100  C C   . GLY A 49  ? 0.99384 1.38200 0.83429 0.02891  -0.06622 0.01009  48  GLY A C   
101  O O   . GLY A 49  ? 1.06857 1.46271 0.91547 0.02990  -0.07811 0.01438  48  GLY A O   
102  N N   . PHE A 50  ? 1.05316 1.44793 0.91521 0.03936  -0.05950 0.00776  49  PHE A N   
103  C CA  . PHE A 50  ? 0.94957 1.35872 0.84456 0.05265  -0.06587 0.00995  49  PHE A CA  
104  C C   . PHE A 50  ? 1.00475 1.39565 0.92336 0.05992  -0.05764 0.00044  49  PHE A C   
105  O O   . PHE A 50  ? 1.02474 1.42174 0.97267 0.07209  -0.05562 -0.00161 49  PHE A O   
106  C CB  . PHE A 50  ? 0.86483 1.29258 0.77176 0.06049  -0.06407 0.01308  49  PHE A CB  
107  N N   . GLY A 51  ? 0.88189 0.99984 1.06460 -0.05673 0.07820  -0.02813 50  GLY A N   
108  C CA  . GLY A 51  ? 0.76760 0.88060 0.94860 -0.04261 0.07499  -0.03045 50  GLY A CA  
109  C C   . GLY A 51  ? 0.75917 0.89780 0.95477 -0.04153 0.06854  -0.03864 50  GLY A C   
110  O O   . GLY A 51  ? 0.68707 0.84140 0.89503 -0.05239 0.06989  -0.04461 50  GLY A O   
111  N N   . SER A 52  ? 0.67444 0.81773 0.86868 -0.02798 0.06145  -0.03882 51  SER A N   
112  C CA  . SER A 52  ? 0.55277 0.72100 0.76079 -0.02531 0.05460  -0.04572 51  SER A CA  
113  C C   . SER A 52  ? 0.55358 0.73424 0.76068 -0.01865 0.04534  -0.04276 51  SER A C   
114  O O   . SER A 52  ? 0.53481 0.70169 0.72949 -0.00699 0.04279  -0.03744 51  SER A O   
115  C CB  . SER A 52  ? 0.53059 0.69338 0.73972 -0.01427 0.05470  -0.05030 51  SER A CB  
116  O OG  . SER A 52  ? 0.52827 0.67536 0.73590 -0.01919 0.06319  -0.05253 51  SER A OG  
117  N N   . VAL A 53  ? 0.47277 0.67893 0.69271 -0.02591 0.04027  -0.04616 52  VAL A N   
118  C CA  . VAL A 53  ? 0.47267 0.69197 0.69315 -0.02189 0.03118  -0.04381 52  VAL A CA  
119  C C   . VAL A 53  ? 0.50893 0.75170 0.74388 -0.01708 0.02379  -0.05010 52  VAL A C   
120  O O   . VAL A 53  ? 0.55405 0.81464 0.80332 -0.02562 0.02487  -0.05583 52  VAL A O   
121  C CB  . VAL A 53  ? 0.52732 0.75582 0.74991 -0.03496 0.03108  -0.04147 52  VAL A CB  
122  C CG1 . VAL A 53  ? 0.46505 0.70468 0.68681 -0.02991 0.02131  -0.03895 52  VAL A CG1 
123  C CG2 . VAL A 53  ? 0.52342 0.72993 0.73312 -0.04060 0.03926  -0.03555 52  VAL A CG2 
124  N N   . TYR A 54  ? 0.48011 0.72336 0.71143 -0.00332 0.01633  -0.04894 53  TYR A N   
125  C CA  . TYR A 54  ? 0.50827 0.77360 0.75303 0.00268  0.00856  -0.05434 53  TYR A CA  
126  C C   . TYR A 54  ? 0.57023 0.85118 0.81862 0.00307  -0.00110 -0.05279 53  TYR A C   
127  O O   . TYR A 54  ? 0.53235 0.80155 0.76800 0.00699  -0.00359 -0.04706 53  TYR A O   
128  C CB  . TYR A 54  ? 0.49549 0.75075 0.73461 0.01922  0.00667  -0.05518 53  TYR A CB  
129  C CG  . TYR A 54  ? 0.49056 0.73119 0.72700 0.02048  0.01511  -0.05760 53  TYR A CG  
130  C CD1 . TYR A 54  ? 0.44563 0.65819 0.66655 0.02101  0.02269  -0.05275 53  TYR A CD1 
131  C CD2 . TYR A 54  ? 0.49514 0.74987 0.74459 0.02139  0.01545  -0.06468 53  TYR A CD2 
132  C CE1 . TYR A 54  ? 0.46625 0.66443 0.68480 0.02205  0.03004  -0.05517 53  TYR A CE1 
133  C CE2 . TYR A 54  ? 0.44134 0.68210 0.68785 0.02303  0.02277  -0.06729 53  TYR A CE2 
134  C CZ  . TYR A 54  ? 0.48801 0.70011 0.71909 0.02324  0.02986  -0.06265 53  TYR A CZ  
135  O OH  . TYR A 54  ? 0.46350 0.66061 0.69166 0.02468  0.03683  -0.06541 53  TYR A OH  
136  N N   . SER A 55  ? 0.56178 0.86908 0.82755 -0.00080 -0.00655 -0.05788 54  SER A N   
137  C CA  . SER A 55  ? 0.58108 0.90402 0.85196 0.00145  -0.01698 -0.05735 54  SER A CA  
138  C C   . SER A 55  ? 0.58253 0.90027 0.84715 0.01882  -0.02414 -0.05667 54  SER A C   
139  O O   . SER A 55  ? 0.63099 0.94420 0.89545 0.02822  -0.02263 -0.05914 54  SER A O   
140  C CB  . SER A 55  ? 0.58354 0.93591 0.87563 -0.00685 -0.02066 -0.06289 54  SER A CB  
141  O OG  . SER A 55  ? 0.64137 1.00852 0.93915 -0.00549 -0.03098 -0.06246 54  SER A OG  
142  N N   . GLY A 56  ? 0.59129 0.90940 0.85019 0.02353  -0.03216 -0.05343 55  GLY A N   
143  C CA  . GLY A 56  ? 0.58001 0.89224 0.83133 0.04042  -0.03939 -0.05249 55  GLY A CA  
144  C C   . GLY A 56  ? 0.62276 0.94835 0.87742 0.04299  -0.05098 -0.05219 55  GLY A C   
145  O O   . GLY A 56  ? 0.66241 0.99656 0.92102 0.03212  -0.05281 -0.05122 55  GLY A O   
146  N N   . ILE A 57  ? 0.62890 0.95609 0.88189 0.05787  -0.05910 -0.05331 56  ILE A N   
147  C CA  . ILE A 57  ? 0.68806 1.02593 0.94283 0.06317  -0.07122 -0.05340 56  ILE A CA  
148  C C   . ILE A 57  ? 0.73398 1.05359 0.97081 0.08101  -0.07512 -0.05003 56  ILE A C   
149  O O   . ILE A 57  ? 0.79846 1.11256 1.03306 0.09239  -0.07422 -0.05156 56  ILE A O   
150  C CB  . ILE A 57  ? 0.70423 1.07103 0.98147 0.06249  -0.07953 -0.06002 56  ILE A CB  
151  C CG1 . ILE A 57  ? 0.62136 1.00670 0.91597 0.04476  -0.07578 -0.06279 56  ILE A CG1 
152  N N   . ARG A 58  ? 0.74767 1.05761 0.97110 0.08393  -0.07931 -0.04540 57  ARG A N   
153  C CA  . ARG A 58  ? 0.79677 1.09016 1.00244 0.10139  -0.08372 -0.04194 57  ARG A CA  
154  C C   . ARG A 58  ? 0.87484 1.18566 1.09040 0.11245  -0.09657 -0.04701 57  ARG A C   
155  O O   . ARG A 58  ? 0.88363 1.21300 1.11060 0.10786  -0.10568 -0.04984 57  ARG A O   
156  C CB  . ARG A 58  ? 0.80885 1.08807 0.99748 0.10116  -0.08442 -0.03558 57  ARG A CB  
157  C CG  . ARG A 58  ? 0.82406 1.08439 0.99209 0.11933  -0.08799 -0.03113 57  ARG A CG  
158  C CD  . ARG A 58  ? 0.84765 1.09137 0.99731 0.11812  -0.08561 -0.02391 57  ARG A CD  
159  N NE  . ARG A 58  ? 0.85187 1.11086 1.00868 0.10948  -0.09303 -0.02533 57  ARG A NE  
160  C CZ  . ARG A 58  ? 0.83146 1.08113 0.97567 0.10623  -0.09211 -0.02011 57  ARG A CZ  
161  N NH1 . ARG A 58  ? 0.79618 1.02196 0.92039 0.11040  -0.08379 -0.01275 57  ARG A NH1 
162  N NH2 . ARG A 58  ? 0.81567 1.08035 0.96764 0.09864  -0.09960 -0.02220 57  ARG A NH2 
163  N N   . VAL A 59  ? 0.89589 1.20068 1.10731 0.12703  -0.09745 -0.04825 58  VAL A N   
164  C CA  . VAL A 59  ? 0.89178 1.21439 1.11421 0.13775  -0.10918 -0.05369 58  VAL A CA  
165  C C   . VAL A 59  ? 0.96665 1.29010 1.18157 0.14582  -0.12094 -0.05246 58  VAL A C   
166  O O   . VAL A 59  ? 0.98807 1.33183 1.21653 0.14914  -0.13239 -0.05752 58  VAL A O   
167  C CB  . VAL A 59  ? 0.84794 1.16122 1.06475 0.15284  -0.10710 -0.05474 58  VAL A CB  
168  N N   . SER A 60  ? 0.99054 1.29249 1.18421 0.14904  -0.11846 -0.04585 59  SER A N   
169  C CA  . SER A 60  ? 0.94978 1.25047 1.13380 0.15834  -0.12949 -0.04452 59  SER A CA  
170  C C   . SER A 60  ? 0.95759 1.27925 1.15653 0.14670  -0.13780 -0.04785 59  SER A C   
171  O O   . SER A 60  ? 0.98894 1.31959 1.18939 0.15431  -0.15040 -0.05035 59  SER A O   
172  C CB  . SER A 60  ? 0.97344 1.24659 1.13132 0.16341  -0.12365 -0.03618 59  SER A CB  
173  N N   . ASP A 61  ? 0.91297 1.24243 1.12295 0.12847  -0.13124 -0.04808 60  ASP A N   
174  C CA  . ASP A 61  ? 0.89413 1.24210 1.11746 0.11710  -0.13869 -0.05076 60  ASP A CA  
175  C C   . ASP A 61  ? 0.91402 1.27843 1.15727 0.09862  -0.13262 -0.05360 60  ASP A C   
176  O O   . ASP A 61  ? 0.90945 1.28542 1.16131 0.08686  -0.13604 -0.05442 60  ASP A O   
177  C CB  . ASP A 61  ? 0.88771 1.22156 1.09364 0.11553  -0.13924 -0.04523 60  ASP A CB  
178  C CG  . ASP A 61  ? 0.90175 1.21442 1.09266 0.10955  -0.12507 -0.03866 60  ASP A CG  
179  O OD1 . ASP A 61  ? 0.88810 1.19764 1.08327 0.10501  -0.11501 -0.03884 60  ASP A OD1 
180  O OD2 . ASP A 61  ? 0.89652 1.19577 1.07143 0.10956  -0.12410 -0.03341 60  ASP A OD2 
181  N N   . ASN A 62  ? 0.94049 1.30598 1.19073 0.09610  -0.12386 -0.05515 61  ASN A N   
182  C CA  . ASN A 62  ? 0.88205 1.26321 1.15074 0.07970  -0.11763 -0.05803 61  ASN A CA  
183  C C   . ASN A 62  ? 0.84762 1.22222 1.11132 0.06480  -0.11060 -0.05414 61  ASN A C   
184  O O   . ASN A 62  ? 0.86654 1.25753 1.14572 0.05044  -0.10964 -0.05646 61  ASN A O   
185  C CB  . ASN A 62  ? 0.89292 1.30323 1.18577 0.07556  -0.12733 -0.06425 61  ASN A CB  
186  C CG  . ASN A 62  ? 0.93684 1.35490 1.23767 0.08666  -0.13073 -0.06824 61  ASN A CG  
187  O OD1 . ASN A 62  ? 0.97020 1.38429 1.26401 0.10108  -0.13899 -0.06868 61  ASN A OD1 
188  N ND2 . ASN A 62  ? 0.93133 1.35858 1.24511 0.07990  -0.12377 -0.07071 61  ASN A ND2 
189  N N   . LEU A 63  ? 0.82115 1.17209 1.06331 0.06822  -0.10547 -0.04806 62  LEU A N   
190  C CA  . LEU A 63  ? 0.75468 1.09846 0.99111 0.05480  -0.09821 -0.04411 62  LEU A CA  
191  C C   . LEU A 63  ? 0.73281 1.07274 0.97315 0.04498  -0.08512 -0.04412 62  LEU A C   
192  O O   . LEU A 63  ? 0.74874 1.07426 0.98093 0.05237  -0.07864 -0.04288 62  LEU A O   
193  C CB  . LEU A 63  ? 0.78322 1.10367 0.99554 0.06213  -0.09699 -0.03733 62  LEU A CB  
194  C CG  . LEU A 63  ? 0.73194 1.04439 0.93671 0.04958  -0.09011 -0.03277 62  LEU A CG  
195  N N   . PRO A 64  ? 0.63966 0.99188 0.89218 0.02880  -0.08121 -0.04568 63  PRO A N   
196  C CA  . PRO A 64  ? 0.67297 1.02170 0.92900 0.01940  -0.06903 -0.04610 63  PRO A CA  
197  C C   . PRO A 64  ? 0.64015 0.96266 0.87628 0.01989  -0.05934 -0.03999 63  PRO A C   
198  O O   . PRO A 64  ? 0.67048 0.98440 0.89578 0.01631  -0.05894 -0.03546 63  PRO A O   
199  C CB  . PRO A 64  ? 0.65760 1.02504 0.92885 0.00257  -0.06860 -0.04842 63  PRO A CB  
200  C CG  . PRO A 64  ? 0.65683 1.04207 0.93811 0.00443  -0.08143 -0.05091 63  PRO A CG  
201  C CD  . PRO A 64  ? 0.64544 1.01626 0.91005 0.01871  -0.08822 -0.04763 63  PRO A CD  
202  N N   . VAL A 65  ? 0.62157 0.93132 0.85310 0.02451  -0.05150 -0.03984 64  VAL A N   
203  C CA  . VAL A 65  ? 0.58814 0.87230 0.80192 0.02531  -0.04175 -0.03409 64  VAL A CA  
204  C C   . VAL A 65  ? 0.60486 0.88671 0.82490 0.01610  -0.03088 -0.03629 64  VAL A C   
205  O O   . VAL A 65  ? 0.59632 0.89314 0.83151 0.01391  -0.03104 -0.04210 64  VAL A O   
206  C CB  . VAL A 65  ? 0.58416 0.84873 0.78137 0.04297  -0.04307 -0.03051 64  VAL A CB  
207  C CG1 . VAL A 65  ? 0.60262 0.86896 0.79252 0.05280  -0.05410 -0.02853 64  VAL A CG1 
208  C CG2 . VAL A 65  ? 0.61589 0.88391 0.82032 0.05175  -0.04345 -0.03518 64  VAL A CG2 
209  N N   . ALA A 66  ? 0.53764 0.80074 0.74591 0.01074  -0.02140 -0.03160 65  ALA A N   
210  C CA  . ALA A 66  ? 0.51698 0.77275 0.72778 0.00351  -0.01068 -0.03309 65  ALA A CA  
211  C C   . ALA A 66  ? 0.49435 0.72364 0.68896 0.01416  -0.00488 -0.02885 65  ALA A C   
212  O O   . ALA A 66  ? 0.47011 0.68188 0.64855 0.01850  -0.00347 -0.02214 65  ALA A O   
213  C CB  . ALA A 66  ? 0.43346 0.68954 0.64542 -0.01276 -0.00393 -0.03154 65  ALA A CB  
214  N N   . ILE A 67  ? 0.45887 0.68518 0.65760 0.01863  -0.00151 -0.03259 66  ILE A N   
215  C CA  . ILE A 67  ? 0.48892 0.69050 0.67338 0.02977  0.00345  -0.02920 66  ILE A CA  
216  C C   . ILE A 67  ? 0.47038 0.65854 0.65365 0.01984  0.01512  -0.02897 66  ILE A C   
217  O O   . ILE A 67  ? 0.46431 0.66101 0.65947 0.01451  0.01822  -0.03498 66  ILE A O   
218  C CB  . ILE A 67  ? 0.49288 0.69902 0.68154 0.04342  -0.00156 -0.03357 66  ILE A CB  
219  C CG1 . ILE A 67  ? 0.44615 0.66751 0.63769 0.05242  -0.01378 -0.03440 66  ILE A CG1 
220  C CG2 . ILE A 67  ? 0.45648 0.63570 0.62931 0.05532  0.00359  -0.02970 66  ILE A CG2 
221  C CD1 . ILE A 67  ? 0.53178 0.76160 0.72977 0.06532  -0.01963 -0.03930 66  ILE A CD1 
222  N N   . LYS A 68  ? 0.40091 0.56813 0.56992 0.01758  0.02155  -0.02208 67  LYS A N   
223  C CA  . LYS A 68  ? 0.47180 0.62615 0.63958 0.00653  0.03243  -0.02124 67  LYS A CA  
224  C C   . LYS A 68  ? 0.53164 0.65855 0.68603 0.01592  0.03871  -0.01749 67  LYS A C   
225  O O   . LYS A 68  ? 0.48191 0.59201 0.62083 0.02555  0.03841  -0.01047 67  LYS A O   
226  C CB  . LYS A 68  ? 0.41784 0.57003 0.58097 -0.00475 0.03567  -0.01615 67  LYS A CB  
227  C CG  . LYS A 68  ? 0.52214 0.65954 0.68280 -0.01589 0.04685  -0.01441 67  LYS A CG  
228  C CD  . LYS A 68  ? 0.54989 0.68769 0.70653 -0.02641 0.04921  -0.00944 67  LYS A CD  
229  C CE  . LYS A 68  ? 0.61337 0.73519 0.76672 -0.03676 0.06028  -0.00697 67  LYS A CE  
230  N NZ  . LYS A 68  ? 0.52211 0.64848 0.67446 -0.04848 0.06251  -0.00342 67  LYS A NZ  
231  N N   . HIS A 69  ? 0.50044 0.62259 0.66044 0.01333  0.04437  -0.02210 68  HIS A N   
232  C CA  . HIS A 69  ? 0.51381 0.60956 0.66254 0.02098  0.05083  -0.01935 68  HIS A CA  
233  C C   . HIS A 69  ? 0.56720 0.64711 0.71284 0.00849  0.06134  -0.01669 68  HIS A C   
234  O O   . HIS A 69  ? 0.56403 0.65562 0.72129 -0.00530 0.06432  -0.02142 68  HIS A O   
235  C CB  . HIS A 69  ? 0.48938 0.58891 0.64579 0.02774  0.04977  -0.02661 68  HIS A CB  
236  C CG  . HIS A 69  ? 0.49278 0.60845 0.65350 0.04019  0.03966  -0.02968 68  HIS A CG  
237  N ND1 . HIS A 69  ? 0.46094 0.56443 0.61248 0.05697  0.03702  -0.02838 68  HIS A ND1 
238  C CD2 . HIS A 69  ? 0.48735 0.63048 0.66092 0.03826  0.03144  -0.03397 68  HIS A CD2 
239  C CE1 . HIS A 69  ? 0.50520 0.62862 0.66408 0.06487  0.02744  -0.03200 68  HIS A CE1 
240  N NE2 . HIS A 69  ? 0.51019 0.65775 0.68276 0.05354  0.02392  -0.03536 68  HIS A NE2 
241  N N   . VAL A 70  ? 0.51212 0.56556 0.64221 0.01347  0.06695  -0.00904 69  VAL A N   
242  C CA  . VAL A 70  ? 0.58342 0.61918 0.70969 0.00264  0.07718  -0.00563 69  VAL A CA  
243  C C   . VAL A 70  ? 0.64919 0.65732 0.76495 0.01164  0.08289  -0.00293 69  VAL A C   
244  O O   . VAL A 70  ? 0.62805 0.62213 0.73050 0.02555  0.08113  0.00289  69  VAL A O   
245  C CB  . VAL A 70  ? 0.64409 0.67474 0.76146 -0.00260 0.07938  0.00282  69  VAL A CB  
246  C CG1 . VAL A 70  ? 0.71417 0.72649 0.82837 -0.01362 0.09020  0.00644  69  VAL A CG1 
247  C CG2 . VAL A 70  ? 0.62502 0.68230 0.75231 -0.01125 0.07346  0.00008  69  VAL A CG2 
248  N N   . GLU A 71  ? 0.62581 0.62574 0.74715 0.00400  0.08956  -0.00719 70  GLU A N   
249  C CA  . GLU A 71  ? 0.70366 0.67608 0.81559 0.01132  0.09540  -0.00494 70  GLU A CA  
250  C C   . GLU A 71  ? 0.72664 0.67436 0.82487 0.00929  0.10292  0.00544  70  GLU A C   
251  O O   . GLU A 71  ? 0.73859 0.68867 0.83906 -0.00379 0.10709  0.00817  70  GLU A O   
252  C CB  . GLU A 71  ? 0.72361 0.69484 0.84599 0.00334  0.09992  -0.01315 70  GLU A CB  
253  C CG  . GLU A 71  ? 0.69923 0.68899 0.83248 0.00916  0.09366  -0.02277 70  GLU A CG  
254  C CD  . GLU A 71  ? 0.75067 0.73997 0.89384 0.00115  0.09816  -0.03109 70  GLU A CD  
255  O OE1 . GLU A 71  ? 0.81053 0.78794 0.95385 -0.01068 0.10551  -0.03005 70  GLU A OE1 
256  O OE2 . GLU A 71  ? 0.66777 0.66894 0.81867 0.00687  0.09424  -0.03879 70  GLU A OE2 
257  N N   . LYS A 72  ? 0.79617 0.72023 0.88008 0.02261  0.10481  0.01145  71  LYS A N   
258  C CA  . LYS A 72  ? 0.82378 0.72324 0.89387 0.02211  0.11231  0.02218  71  LYS A CA  
259  C C   . LYS A 72  ? 0.88225 0.76784 0.95671 0.00773  0.12209  0.02183  71  LYS A C   
260  O O   . LYS A 72  ? 0.91191 0.79013 0.98286 -0.00134 0.12801  0.02851  71  LYS A O   
261  C CB  . LYS A 72  ? 0.81576 0.69223 0.86980 0.03995  0.11247  0.02827  71  LYS A CB  
262  C CG  . LYS A 72  ? 0.79056 0.67671 0.83676 0.05455  0.10364  0.03120  71  LYS A CG  
263  C CD  . LYS A 72  ? 0.87217 0.73350 0.90117 0.07207  0.10472  0.03792  71  LYS A CD  
264  C CE  . LYS A 72  ? 0.85273 0.72284 0.87282 0.08678  0.09594  0.04125  71  LYS A CE  
265  N NZ  . LYS A 72  ? 0.90096 0.74675 0.90337 0.10453  0.09701  0.04801  71  LYS A NZ  
266  N N   . ASP A 73  ? 0.88430 0.76655 0.96664 0.00558  0.12376  0.01389  72  ASP A N   
267  C CA  . ASP A 73  ? 0.96868 0.83679 1.05549 -0.00741 0.13247  0.01259  72  ASP A CA  
268  C C   . ASP A 73  ? 0.95092 0.83787 1.05040 -0.02549 0.13390  0.00900  72  ASP A C   
269  O O   . ASP A 73  ? 1.00351 0.87953 1.10645 -0.03752 0.14124  0.00895  72  ASP A O   
270  C CB  . ASP A 73  ? 1.04886 0.91013 1.14087 -0.00413 0.13281  0.00400  72  ASP A CB  
271  C CG  . ASP A 73  ? 1.13172 0.96916 1.21021 0.01274  0.13317  0.00809  72  ASP A CG  
272  O OD1 . ASP A 73  ? 1.15276 0.97718 1.21746 0.02118  0.13405  0.01810  72  ASP A OD1 
273  O OD2 . ASP A 73  ? 1.17723 1.00891 1.25839 0.01801  0.13257  0.00132  72  ASP A OD2 
274  N N   . ARG A 74  ? 0.91514 0.82967 1.02163 -0.02769 0.12702  0.00601  73  ARG A N   
275  C CA  . ARG A 74  ? 0.89417 0.82787 1.01224 -0.04402 0.12778  0.00261  73  ARG A CA  
276  C C   . ARG A 74  ? 0.91182 0.85142 1.02419 -0.04711 0.12733  0.01078  73  ARG A C   
277  O O   . ARG A 74  ? 0.94743 0.90753 1.06865 -0.05796 0.12553  0.00805  73  ARG A O   
278  C CB  . ARG A 74  ? 0.85066 0.81262 0.98291 -0.04604 0.12070  -0.00798 73  ARG A CB  
279  N N   . ILE A 75  ? 0.93479 0.85673 1.03208 -0.03741 0.12897  0.02079  74  ILE A N   
280  C CA  . ILE A 75  ? 0.94512 0.87116 1.03508 -0.03829 0.12847  0.02907  74  ILE A CA  
281  C C   . ILE A 75  ? 0.97126 0.87925 1.05675 -0.04812 0.13859  0.03643  74  ILE A C   
282  O O   . ILE A 75  ? 0.97512 0.85754 1.05271 -0.04433 0.14508  0.04127  74  ILE A O   
283  C CB  . ILE A 75  ? 0.89901 0.81863 0.97465 -0.02055 0.12343  0.03561  74  ILE A CB  
284  C CG1 . ILE A 75  ? 0.83900 0.78007 0.92082 -0.01203 0.11268  0.02816  74  ILE A CG1 
285  C CG2 . ILE A 75  ? 0.91287 0.83257 0.97886 -0.02093 0.12416  0.04504  74  ILE A CG2 
286  C CD1 . ILE A 75  ? 0.81372 0.74816 0.88242 0.00652  0.10709  0.03299  74  ILE A CD1 
287  N N   . SER A 76  ? 1.07117 0.99244 1.16186 -0.06068 0.13999  0.03745  75  SER A N   
288  C CA  . SER A 76  ? 1.04774 0.95485 1.13618 -0.07135 0.14957  0.04394  75  SER A CA  
289  C C   . SER A 76  ? 1.02456 0.91918 1.09720 -0.06389 0.15209  0.05653  75  SER A C   
290  O O   . SER A 76  ? 1.08621 0.95590 1.14913 -0.05994 0.15913  0.06420  75  SER A O   
291  C CB  . SER A 76  ? 1.07852 1.00558 1.17991 -0.08829 0.15028  0.03905  75  SER A CB  
292  N N   . ASP A 77  ? 0.98296 0.89434 1.05259 -0.06159 0.14644  0.05890  76  ASP A N   
293  C CA  . ASP A 77  ? 0.99087 0.89330 1.04557 -0.05480 0.14836  0.07048  76  ASP A CA  
294  C C   . ASP A 77  ? 0.91079 0.80970 0.95338 -0.03579 0.14133  0.07318  76  ASP A C   
295  O O   . ASP A 77  ? 0.85821 0.77488 0.90578 -0.03049 0.13184  0.06617  76  ASP A O   
296  C CB  . ASP A 77  ? 0.96975 0.89183 1.02745 -0.06356 0.14644  0.07165  76  ASP A CB  
297  C CG  . ASP A 77  ? 0.98193 0.90907 1.05174 -0.08217 0.15294  0.06870  76  ASP A CG  
298  N N   . TRP A 78  ? 0.91819 0.79445 0.94514 -0.02557 0.14603  0.08339  77  TRP A N   
299  C CA  . TRP A 78  ? 0.89151 0.76187 0.90486 -0.00662 0.14012  0.08716  77  TRP A CA  
300  C C   . TRP A 78  ? 0.89319 0.76231 0.89249 -0.00067 0.14014  0.09737  77  TRP A C   
301  O O   . TRP A 78  ? 0.96545 0.82760 0.96160 -0.00876 0.14810  0.10465  77  TRP A O   
302  C CB  . TRP A 78  ? 0.90669 0.75017 0.91141 0.00323  0.14506  0.09068  77  TRP A CB  
303  C CG  . TRP A 78  ? 0.92076 0.76605 0.93603 0.00347  0.14222  0.08029  77  TRP A CG  
304  C CD1 . TRP A 78  ? 0.95233 0.79531 0.98026 -0.00927 0.14719  0.07396  77  TRP A CD1 
305  C CD2 . TRP A 78  ? 0.89386 0.74396 0.90783 0.01759  0.13364  0.07489  77  TRP A CD2 
306  N NE1 . TRP A 78  ? 0.97453 0.82050 1.00864 -0.00368 0.14238  0.06504  77  TRP A NE1 
307  C CE2 . TRP A 78  ? 0.94975 0.80040 0.97578 0.01266  0.13417  0.06555  77  TRP A CE2 
308  C CE3 . TRP A 78  ? 0.88272 0.73714 0.88665 0.03412  0.12537  0.07684  77  TRP A CE3 
309  C CZ2 . TRP A 78  ? 0.90503 0.76078 0.93345 0.02370  0.12708  0.05846  77  TRP A CZ2 
310  C CZ3 . TRP A 78  ? 0.90728 0.76690 0.91416 0.04475  0.11813  0.06963  77  TRP A CZ3 
311  C CH2 . TRP A 78  ? 0.87542 0.73584 0.89449 0.03950  0.11921  0.06070  77  TRP A CH2 
312  N N   . GLY A 79  ? 0.88924 0.76567 0.88026 0.01381  0.13095  0.09766  78  GLY A N   
313  C CA  . GLY A 79  ? 0.89647 0.77203 0.87284 0.02201  0.12952  0.10664  78  GLY A CA  
314  C C   . GLY A 79  ? 0.98658 0.84869 0.94667 0.04261  0.12565  0.11150  78  GLY A C   
315  O O   . GLY A 79  ? 1.02747 0.88055 0.98773 0.05034  0.12437  0.10809  78  GLY A O   
316  N N   . GLU A 80  ? 1.02614 0.88730 0.97177 0.05176  0.12369  0.11941  79  GLU A N   
317  C CA  . GLU A 80  ? 1.16592 1.01448 1.09403 0.07210  0.12001  0.12503  79  GLU A CA  
318  C C   . GLU A 80  ? 1.19723 1.06302 1.11939 0.08060  0.10932  0.12452  79  GLU A C   
319  O O   . GLU A 80  ? 1.19736 1.07205 1.11834 0.07398  0.11011  0.12775  79  GLU A O   
320  C CB  . GLU A 80  ? 1.16322 0.98451 1.07475 0.07733  0.13120  0.13837  79  GLU A CB  
321  N N   . LEU A 81  ? 1.23311 1.10361 1.15174 0.09531  0.09917  0.12021  80  LEU A N   
322  C CA  . LEU A 81  ? 1.32355 1.20870 1.23576 0.10531  0.08807  0.11938  80  LEU A CA  
323  C C   . LEU A 81  ? 1.37075 1.23899 1.25998 0.11976  0.09081  0.13141  80  LEU A C   
324  O O   . LEU A 81  ? 1.38740 1.23205 1.26576 0.12410  0.10053  0.13995  80  LEU A O   
325  C CB  . LEU A 81  ? 1.28802 1.18459 1.20576 0.11573  0.07618  0.11016  80  LEU A CB  
326  N N   . PRO A 82  ? 1.39020 1.26989 1.27155 0.12718  0.08259  0.13249  81  PRO A N   
327  C CA  . PRO A 82  ? 1.39466 1.25916 1.25290 0.14343  0.08391  0.14339  81  PRO A CA  
328  C C   . PRO A 82  ? 1.39629 1.24077 1.24178 0.16063  0.08473  0.14710  81  PRO A C   
329  O O   . PRO A 82  ? 1.43353 1.25718 1.26120 0.16969  0.09235  0.15840  81  PRO A O   
330  C CB  . PRO A 82  ? 1.37826 1.26231 1.23381 0.15043  0.07070  0.13939  81  PRO A CB  
331  C CG  . PRO A 82  ? 1.38622 1.29440 1.26307 0.13313  0.06607  0.12926  81  PRO A CG  
332  C CD  . PRO A 82  ? 1.36730 1.27267 1.26010 0.11791  0.07436  0.12544  81  PRO A CD  
333  N N   . ASN A 83  ? 1.40888 1.25923 1.26294 0.16561  0.07725  0.13807  82  ASN A N   
334  C CA  . ASN A 83  ? 1.39021 1.22210 1.23312 0.18188  0.07773  0.14073  82  ASN A CA  
335  C C   . ASN A 83  ? 1.41511 1.22434 1.25822 0.17585  0.09110  0.14565  82  ASN A C   
336  O O   . ASN A 83  ? 1.40074 1.19183 1.23374 0.18890  0.09291  0.14877  82  ASN A O   
337  C CB  . ASN A 83  ? 1.36722 1.21404 1.22057 0.18851  0.06551  0.12907  82  ASN A CB  
338  N N   . GLY A 84  ? 1.42371 1.23327 1.27799 0.15675  0.10019  0.14622  83  GLY A N   
339  C CA  . GLY A 84  ? 1.40566 1.19408 1.26139 0.14957  0.11273  0.15049  83  GLY A CA  
340  C C   . GLY A 84  ? 1.38243 1.17445 1.25539 0.14186  0.11193  0.14010  83  GLY A C   
341  O O   . GLY A 84  ? 1.37266 1.14840 1.24914 0.13369  0.12204  0.14229  83  GLY A O   
342  N N   . THR A 85  ? 1.35110 1.16386 1.23504 0.14421  0.10030  0.12890  84  THR A N   
343  C CA  . THR A 85  ? 1.29146 1.10916 1.19163 0.13789  0.09916  0.11877  84  THR A CA  
344  C C   . THR A 85  ? 1.21690 1.04333 1.13450 0.11558  0.10525  0.11454  84  THR A C   
345  O O   . THR A 85  ? 1.17869 1.02229 1.10271 0.10522  0.10335  0.11331  84  THR A O   
346  C CB  . THR A 85  ? 1.22212 1.06236 1.13056 0.14534  0.08519  0.10822  84  THR A CB  
347  N N   . ARG A 86  ? 1.15644 0.97076 1.08135 0.10857  0.11236  0.11213  85  ARG A N   
348  C CA  . ARG A 86  ? 1.09042 0.91128 1.03171 0.08795  0.11839  0.10768  85  ARG A CA  
349  C C   . ARG A 86  ? 1.03321 0.88085 0.99327 0.08128  0.10948  0.09440  85  ARG A C   
350  O O   . ARG A 86  ? 1.00547 0.85394 0.97155 0.08615  0.10602  0.08726  85  ARG A O   
351  C CB  . ARG A 86  ? 1.08384 0.88033 1.02513 0.08361  0.12912  0.11013  85  ARG A CB  
352  N N   . VAL A 87  ? 0.98374 0.85321 0.95288 0.07040  0.10595  0.09128  86  VAL A N   
353  C CA  . VAL A 87  ? 0.87566 0.77201 0.86259 0.06343  0.09757  0.07949  86  VAL A CA  
354  C C   . VAL A 87  ? 0.82977 0.73459 0.83094 0.04278  0.10356  0.07612  86  VAL A C   
355  O O   . VAL A 87  ? 0.84229 0.73595 0.83894 0.03459  0.11240  0.08325  86  VAL A O   
356  C CB  . VAL A 87  ? 0.83470 0.75154 0.82003 0.07036  0.08604  0.07786  86  VAL A CB  
357  C CG1 . VAL A 87  ? 0.87454 0.78254 0.84525 0.09139  0.07995  0.08110  86  VAL A CG1 
358  C CG2 . VAL A 87  ? 0.84397 0.76465 0.82418 0.06328  0.08838  0.08426  86  VAL A CG2 
359  N N   . PRO A 88  ? 0.75840 0.68302 0.77705 0.03401  0.09921  0.06537  87  PRO A N   
360  C CA  . PRO A 88  ? 0.75745 0.69291 0.78957 0.01475  0.10378  0.06169  87  PRO A CA  
361  C C   . PRO A 88  ? 0.67791 0.62505 0.70761 0.00883  0.10240  0.06592  87  PRO A C   
362  O O   . PRO A 88  ? 0.63025 0.58747 0.65424 0.01769  0.09420  0.06711  87  PRO A O   
363  C CB  . PRO A 88  ? 0.72241 0.67954 0.77185 0.01042  0.09709  0.04952  87  PRO A CB  
364  C CG  . PRO A 88  ? 0.76074 0.71067 0.80619 0.02581  0.09285  0.04719  87  PRO A CG  
365  C CD  . PRO A 88  ? 0.73725 0.67418 0.76427 0.04134  0.09078  0.05620  87  PRO A CD  
366  N N   . MET A 89  ? 0.66179 0.60735 0.69586 -0.00615 0.11038  0.06803  88  MET A N   
367  C CA  . MET A 89  ? 0.69194 0.64873 0.72421 -0.01274 0.10976  0.07186  88  MET A CA  
368  C C   . MET A 89  ? 0.58613 0.57070 0.62849 -0.01498 0.09904  0.06410  88  MET A C   
369  O O   . MET A 89  ? 0.55622 0.54983 0.59286 -0.01258 0.09431  0.06733  88  MET A O   
370  C CB  . MET A 89  ? 0.76082 0.71410 0.79927 -0.02971 0.11972  0.07356  88  MET A CB  
371  C CG  . MET A 89  ? 0.71387 0.67651 0.74929 -0.03645 0.12047  0.07851  88  MET A CG  
372  S SD  . MET A 89  ? 0.86689 0.81354 0.87968 -0.02217 0.12205  0.09203  88  MET A SD  
373  C CE  . MET A 89  ? 0.77767 0.69280 0.78283 -0.02085 0.13482  0.09986  88  MET A CE  
374  N N   . GLU A 90  ? 0.56418 0.56226 0.62135 -0.01921 0.09507  0.05399  89  GLU A N   
375  C CA  . GLU A 90  ? 0.54631 0.57079 0.61415 -0.02145 0.08504  0.04663  89  GLU A CA  
376  C C   . GLU A 90  ? 0.52783 0.55641 0.58636 -0.00595 0.07520  0.04867  89  GLU A C   
377  O O   . GLU A 90  ? 0.45896 0.50434 0.51934 -0.00719 0.06807  0.04753  89  GLU A O   
378  C CB  . GLU A 90  ? 0.53613 0.57212 0.62006 -0.02601 0.08293  0.03619  89  GLU A CB  
379  C CG  . GLU A 90  ? 0.48459 0.54810 0.58091 -0.02845 0.07291  0.02854  89  GLU A CG  
380  C CD  . GLU A 90  ? 0.50496 0.58041 0.61741 -0.03366 0.07190  0.01868  89  GLU A CD  
381  O OE1 . GLU A 90  ? 0.49278 0.55509 0.60670 -0.03560 0.07880  0.01727  89  GLU A OE1 
382  O OE2 . GLU A 90  ? 0.47087 0.56886 0.59454 -0.03573 0.06421  0.01238  89  GLU A OE2 
383  N N   . VAL A 91  ? 0.53378 0.54683 0.58201 0.00898  0.07447  0.05158  90  VAL A N   
384  C CA  . VAL A 91  ? 0.52024 0.53582 0.55856 0.02478  0.06509  0.05363  90  VAL A CA  
385  C C   . VAL A 91  ? 0.52764 0.53783 0.55162 0.02745  0.06582  0.06253  90  VAL A C   
386  O O   . VAL A 91  ? 0.51746 0.54040 0.53887 0.03272  0.05676  0.06202  90  VAL A O   
387  C CB  . VAL A 91  ? 0.62395 0.62257 0.65347 0.04044  0.06498  0.05513  90  VAL A CB  
388  C CG1 . VAL A 91  ? 0.63083 0.63061 0.64851 0.05757  0.05554  0.05782  90  VAL A CG1 
389  C CG2 . VAL A 91  ? 0.58554 0.59220 0.62963 0.03872  0.06304  0.04563  90  VAL A CG2 
390  N N   . VAL A 92  ? 0.54712 0.53864 0.56185 0.02378  0.07655  0.07075  91  VAL A N   
391  C CA  . VAL A 92  ? 0.54227 0.52839 0.54309 0.02617  0.07836  0.07978  91  VAL A CA  
392  C C   . VAL A 92  ? 0.53440 0.54223 0.54345 0.01511  0.07393  0.07648  91  VAL A C   
393  O O   . VAL A 92  ? 0.48362 0.49825 0.48469 0.02155  0.06726  0.07897  91  VAL A O   
394  C CB  . VAL A 92  ? 0.60655 0.57024 0.59892 0.02184  0.09172  0.08882  91  VAL A CB  
395  C CG1 . VAL A 92  ? 0.59728 0.55829 0.57721 0.02222  0.09432  0.09788  91  VAL A CG1 
396  C CG2 . VAL A 92  ? 0.68518 0.62567 0.66667 0.03485  0.09553  0.09332  91  VAL A CG2 
397  N N   . LEU A 93  ? 0.50570 0.52456 0.53056 -0.00133 0.07731  0.07061  92  LEU A N   
398  C CA  . LEU A 93  ? 0.48516 0.52389 0.51795 -0.01263 0.07392  0.06762  92  LEU A CA  
399  C C   . LEU A 93  ? 0.47059 0.52991 0.50984 -0.00788 0.06075  0.06063  92  LEU A C   
400  O O   . LEU A 93  ? 0.44815 0.51866 0.48478 -0.00830 0.05503  0.06146  92  LEU A O   
401  C CB  . LEU A 93  ? 0.45558 0.50095 0.50376 -0.03060 0.08058  0.06259  92  LEU A CB  
402  C CG  . LEU A 93  ? 0.48193 0.50800 0.52649 -0.03722 0.09354  0.06843  92  LEU A CG  
403  C CD1 . LEU A 93  ? 0.48639 0.52149 0.54736 -0.05458 0.09842  0.06186  92  LEU A CD1 
404  C CD2 . LEU A 93  ? 0.45598 0.47311 0.48670 -0.03632 0.09843  0.07872  92  LEU A CD2 
405  N N   . LEU A 94  ? 0.43546 0.50018 0.48352 -0.00343 0.05577  0.05365  93  LEU A N   
406  C CA  . LEU A 94  ? 0.48204 0.56673 0.53774 0.00088  0.04329  0.04692  93  LEU A CA  
407  C C   . LEU A 94  ? 0.47653 0.55807 0.51750 0.01624  0.03535  0.05148  93  LEU A C   
408  O O   . LEU A 94  ? 0.47484 0.57224 0.51847 0.01664  0.02606  0.04875  93  LEU A O   
409  C CB  . LEU A 94  ? 0.44744 0.53710 0.51457 0.00395  0.04033  0.03934  93  LEU A CB  
410  C CG  . LEU A 94  ? 0.47029 0.57190 0.55569 -0.01125 0.04413  0.03189  93  LEU A CG  
411  C CD1 . LEU A 94  ? 0.46837 0.57063 0.56206 -0.00610 0.04278  0.02573  93  LEU A CD1 
412  C CD2 . LEU A 94  ? 0.42874 0.55475 0.52633 -0.02115 0.03759  0.02664  93  LEU A CD2 
413  N N   . LYS A 95  ? 0.51973 0.58054 0.54479 0.02923  0.03872  0.05844  94  LYS A N   
414  C CA  . LYS A 95  ? 0.53605 0.59277 0.54556 0.04480  0.03148  0.06308  94  LYS A CA  
415  C C   . LYS A 95  ? 0.53067 0.58989 0.53191 0.04098  0.03175  0.06837  94  LYS A C   
416  O O   . LYS A 95  ? 0.58428 0.65170 0.57992 0.04869  0.02207  0.06810  94  LYS A O   
417  C CB  . LYS A 95  ? 0.55030 0.58300 0.54352 0.05921  0.03636  0.07021  94  LYS A CB  
418  C CG  . LYS A 95  ? 0.63210 0.66230 0.63031 0.06768  0.03345  0.06512  94  LYS A CG  
419  C CD  . LYS A 95  ? 0.71237 0.71830 0.69242 0.08342  0.03751  0.07279  94  LYS A CD  
420  N N   . LYS A 96  ? 0.51801 0.57057 0.51858 0.02924  0.04251  0.07298  95  LYS A N   
421  C CA  . LYS A 96  ? 0.50256 0.55700 0.49465 0.02598  0.04354  0.07848  95  LYS A CA  
422  C C   . LYS A 96  ? 0.51147 0.58945 0.51543 0.01676  0.03526  0.07163  95  LYS A C   
423  O O   . LYS A 96  ? 0.53137 0.61393 0.52715 0.01919  0.03091  0.07449  95  LYS A O   
424  C CB  . LYS A 96  ? 0.51002 0.55190 0.49949 0.01553  0.05742  0.08505  95  LYS A CB  
425  C CG  . LYS A 96  ? 0.56581 0.58255 0.54042 0.02553  0.06588  0.09398  95  LYS A CG  
426  C CD  . LYS A 96  ? 0.59995 0.60492 0.57567 0.01342  0.07979  0.09933  95  LYS A CD  
427  C CE  . LYS A 96  ? 0.60075 0.60993 0.57118 0.00672  0.08317  0.10487  95  LYS A CE  
428  N NZ  . LYS A 96  ? 0.70867 0.70962 0.65907 0.02180  0.08064  0.11328  95  LYS A NZ  
429  N N   . VAL A 97  ? 0.44416 0.53703 0.46688 0.00663  0.03289  0.06272  96  VAL A N   
430  C CA  . VAL A 97  ? 0.42851 0.54359 0.46324 -0.00254 0.02533  0.05630  96  VAL A CA  
431  C C   . VAL A 97  ? 0.50485 0.63364 0.54599 0.00558  0.01204  0.04950  96  VAL A C   
432  O O   . VAL A 97  ? 0.49661 0.64351 0.54695 -0.00041 0.00445  0.04446  96  VAL A O   
433  C CB  . VAL A 97  ? 0.49652 0.62159 0.54845 -0.02056 0.03141  0.05105  96  VAL A CB  
434  C CG1 . VAL A 97  ? 0.43411 0.54726 0.48084 -0.02949 0.04394  0.05737  96  VAL A CG1 
435  C CG2 . VAL A 97  ? 0.42370 0.55023 0.48786 -0.02096 0.03195  0.04473  96  VAL A CG2 
436  N N   . SER A 98  ? 0.53234 0.59584 0.55278 0.00141  -0.09896 -0.03466 97  SER A N   
437  C CA  . SER A 98  ? 0.60180 0.69508 0.64830 0.00180  -0.10675 -0.02591 97  SER A CA  
438  C C   . SER A 98  ? 0.64040 0.73809 0.69548 -0.00628 -0.12321 -0.02644 97  SER A C   
439  O O   . SER A 98  ? 0.84894 0.95900 0.91250 0.00000  -0.13103 -0.02333 97  SER A O   
440  C CB  . SER A 98  ? 0.67267 0.77536 0.72062 0.01778  -0.10254 -0.02133 97  SER A CB  
441  N N   . SER A 99  ? 0.71781 0.80630 0.77101 -0.01958 -0.12888 -0.03076 98  SER A N   
442  C CA  . SER A 99  ? 0.77911 0.86954 0.83914 -0.02822 -0.14427 -0.03226 98  SER A CA  
443  C C   . SER A 99  ? 0.85188 0.96988 0.94022 -0.03714 -0.15150 -0.02591 98  SER A C   
444  O O   . SER A 99  ? 0.93954 1.06319 1.03704 -0.04401 -0.16446 -0.02665 98  SER A O   
445  C CB  . SER A 99  ? 0.78986 0.85571 0.83314 -0.03808 -0.14737 -0.04110 98  SER A CB  
446  N N   . GLY A 100 ? 0.87060 1.00550 0.97270 -0.03773 -0.14298 -0.02016 99  GLY A N   
447  C CA  . GLY A 100 ? 0.85993 1.01865 0.98733 -0.04796 -0.14739 -0.01476 99  GLY A CA  
448  C C   . GLY A 100 ? 0.94350 1.09432 1.06941 -0.06037 -0.14448 -0.01485 99  GLY A C   
449  O O   . GLY A 100 ? 0.91336 1.08179 1.05815 -0.06894 -0.14466 -0.00965 99  GLY A O   
450  N N   . PHE A 101 ? 0.90088 1.02546 1.00432 -0.06146 -0.14176 -0.02120 100 PHE A N   
451  C CA  . PHE A 101 ? 0.73191 0.84741 0.83056 -0.07039 -0.13831 -0.02187 100 PHE A CA  
452  C C   . PHE A 101 ? 0.71616 0.84442 0.82167 -0.06714 -0.12510 -0.01551 100 PHE A C   
453  O O   . PHE A 101 ? 0.79345 0.91986 0.89070 -0.05632 -0.11461 -0.01601 100 PHE A O   
454  C CB  . PHE A 101 ? 0.71868 0.80586 0.79158 -0.06936 -0.13697 -0.03168 100 PHE A CB  
455  C CG  . PHE A 101 ? 0.67614 0.75318 0.74084 -0.07504 -0.13246 -0.03351 100 PHE A CG  
456  C CD1 . PHE A 101 ? 0.69280 0.76844 0.76292 -0.08680 -0.14067 -0.03235 100 PHE A CD1 
457  C CD2 . PHE A 101 ? 0.63544 0.70346 0.68583 -0.06805 -0.12013 -0.03686 100 PHE A CD2 
458  C CE1 . PHE A 101 ? 0.63248 0.69697 0.69250 -0.09052 -0.13701 -0.03401 100 PHE A CE1 
459  C CE2 . PHE A 101 ? 0.58093 0.63988 0.62257 -0.07189 -0.11667 -0.03913 100 PHE A CE2 
460  C CZ  . PHE A 101 ? 0.55614 0.61280 0.60185 -0.08264 -0.12530 -0.03748 100 PHE A CZ  
461  N N   . SER A 102 ? 0.71470 0.85503 0.83467 -0.07685 -0.12510 -0.00968 101 SER A N   
462  C CA  . SER A 102 ? 0.67792 0.83399 0.80777 -0.07508 -0.11305 -0.00273 101 SER A CA  
463  C C   . SER A 102 ? 0.59174 0.73240 0.70284 -0.07050 -0.10151 -0.00490 101 SER A C   
464  O O   . SER A 102 ? 0.58644 0.73883 0.70322 -0.06729 -0.09033 0.00033  101 SER A O   
465  C CB  . SER A 102 ? 0.66016 0.82983 0.80797 -0.08828 -0.11547 0.00341  101 SER A CB  
466  N N   . GLY A 103 ? 0.57774 0.69385 0.66731 -0.07001 -0.10379 -0.01322 102 GLY A N   
467  C CA  . GLY A 103 ? 0.49970 0.60264 0.57215 -0.06590 -0.09359 -0.01672 102 GLY A CA  
468  C C   . GLY A 103 ? 0.48809 0.59111 0.55286 -0.05298 -0.08209 -0.01912 102 GLY A C   
469  O O   . GLY A 103 ? 0.42910 0.52592 0.48287 -0.04894 -0.07199 -0.02131 102 GLY A O   
470  N N   . VAL A 104 ? 0.49288 0.60172 0.56196 -0.04598 -0.08336 -0.01909 103 VAL A N   
471  C CA  . VAL A 104 ? 0.47703 0.58471 0.53832 -0.03329 -0.07219 -0.02088 103 VAL A CA  
472  C C   . VAL A 104 ? 0.46748 0.59959 0.54822 -0.02736 -0.07002 -0.01237 103 VAL A C   
473  O O   . VAL A 104 ? 0.43952 0.58638 0.53710 -0.03181 -0.07951 -0.00797 103 VAL A O   
474  C CB  . VAL A 104 ? 0.49211 0.57841 0.53434 -0.02820 -0.07425 -0.03054 103 VAL A CB  
475  C CG1 . VAL A 104 ? 0.46642 0.53086 0.49092 -0.03431 -0.07668 -0.04071 103 VAL A CG1 
476  C CG2 . VAL A 104 ? 0.47303 0.56303 0.52244 -0.02872 -0.08617 -0.02905 103 VAL A CG2 
477  N N   . ILE A 105 ? 0.43456 0.57196 0.51345 -0.01699 -0.05748 -0.01086 104 ILE A N   
478  C CA  . ILE A 105 ? 0.43866 0.59914 0.53471 -0.00925 -0.05499 -0.00410 104 ILE A CA  
479  C C   . ILE A 105 ? 0.46957 0.62652 0.56323 -0.00269 -0.06350 -0.00619 104 ILE A C   
480  O O   . ILE A 105 ? 0.49383 0.62730 0.56689 0.00117  -0.06400 -0.01317 104 ILE A O   
481  C CB  . ILE A 105 ? 0.50315 0.66752 0.59540 0.00128  -0.03958 -0.00297 104 ILE A CB  
482  C CG1 . ILE A 105 ? 0.47445 0.66829 0.58926 0.00676  -0.03681 0.00484  104 ILE A CG1 
483  C CG2 . ILE A 105 ? 0.44690 0.58942 0.51692 0.01207  -0.03382 -0.01021 104 ILE A CG2 
484  C CD1 . ILE A 105 ? 0.52513 0.74012 0.66020 -0.00404 -0.03662 0.01134  104 ILE A CD1 
485  N N   . ARG A 106 ? 0.44617 0.62639 0.56048 -0.00169 -0.07033 -0.00079 105 ARG A N   
486  C CA  . ARG A 106 ? 0.49151 0.67093 0.60504 0.00456  -0.08037 -0.00227 105 ARG A CA  
487  C C   . ARG A 106 ? 0.48618 0.67490 0.60057 0.02103  -0.07399 0.00003  105 ARG A C   
488  O O   . ARG A 106 ? 0.42875 0.64339 0.56241 0.02426  -0.06966 0.00528  105 ARG A O   
489  C CB  . ARG A 106 ? 0.42697 0.62664 0.56271 -0.00457 -0.09371 0.00066  105 ARG A CB  
490  C CG  . ARG A 106 ? 0.54727 0.74732 0.68246 0.00192  -0.10549 -0.00126 105 ARG A CG  
491  N N   . LEU A 107 ? 0.47146 0.63822 0.56419 0.03137  -0.07305 -0.00425 106 LEU A N   
492  C CA  . LEU A 107 ? 0.48861 0.66000 0.57861 0.04837  -0.06870 -0.00233 106 LEU A CA  
493  C C   . LEU A 107 ? 0.47903 0.66794 0.58278 0.05302  -0.08230 -0.00006 106 LEU A C   
494  O O   . LEU A 107 ? 0.50241 0.67824 0.59726 0.05053  -0.09299 -0.00321 106 LEU A O   
495  C CB  . LEU A 107 ? 0.50211 0.63988 0.56094 0.05719  -0.06140 -0.00798 106 LEU A CB  
496  C CG  . LEU A 107 ? 0.53894 0.67449 0.58907 0.07593  -0.05653 -0.00632 106 LEU A CG  
497  C CD1 . LEU A 107 ? 0.48598 0.63896 0.54679 0.08303  -0.04406 -0.00238 106 LEU A CD1 
498  C CD2 . LEU A 107 ? 0.56897 0.66672 0.58586 0.08198  -0.05090 -0.01261 106 LEU A CD2 
499  N N   . LEU A 108 ? 0.45564 0.67509 0.58129 0.05998  -0.08199 0.00461  107 LEU A N   
500  C CA  . LEU A 108 ? 0.48155 0.72290 0.62340 0.06536  -0.09490 0.00576  107 LEU A CA  
501  C C   . LEU A 108 ? 0.52305 0.75609 0.64986 0.08572  -0.09552 0.00519  107 LEU A C   
502  O O   . LEU A 108 ? 0.52910 0.76451 0.65562 0.09123  -0.10796 0.00397  107 LEU A O   
503  C CB  . LEU A 108 ? 0.44918 0.73096 0.62474 0.06166  -0.09490 0.00962  107 LEU A CB  
504  C CG  . LEU A 108 ? 0.43856 0.72982 0.62969 0.04180  -0.09340 0.01116  107 LEU A CG  
505  C CD1 . LEU A 108 ? 0.49508 0.82471 0.71727 0.03920  -0.09026 0.01459  107 LEU A CD1 
506  C CD2 . LEU A 108 ? 0.51813 0.80303 0.71083 0.02871  -0.10684 0.00871  107 LEU A CD2 
507  N N   . ASP A 109 ? 0.48690 0.70947 0.60024 0.09743  -0.08241 0.00593  108 ASP A N   
508  C CA  . ASP A 109 ? 0.52614 0.73917 0.62354 0.11801  -0.08149 0.00591  108 ASP A CA  
509  C C   . ASP A 109 ? 0.56550 0.76013 0.64515 0.12550  -0.06427 0.00584  108 ASP A C   
510  O O   . ASP A 109 ? 0.50398 0.70017 0.58841 0.11565  -0.05430 0.00601  108 ASP A O   
511  C CB  . ASP A 109 ? 0.55541 0.80517 0.67743 0.12929  -0.08904 0.00846  108 ASP A CB  
512  C CG  . ASP A 109 ? 0.62331 0.86176 0.72729 0.15061  -0.09404 0.00783  108 ASP A CG  
513  O OD1 . ASP A 109 ? 0.58154 0.78222 0.65340 0.15517  -0.09208 0.00583  108 ASP A OD1 
514  O OD2 . ASP A 109 ? 0.64631 0.91358 0.76771 0.16302  -0.09971 0.00890  108 ASP A OD2 
515  N N   . TRP A 110 ? 0.53606 0.71236 0.59411 0.14341  -0.06077 0.00538  109 TRP A N   
516  C CA  . TRP A 110 ? 0.56445 0.72363 0.60560 0.15224  -0.04420 0.00500  109 TRP A CA  
517  C C   . TRP A 110 ? 0.66831 0.82121 0.69591 0.17500  -0.04380 0.00639  109 TRP A C   
518  O O   . TRP A 110 ? 0.65819 0.80703 0.67877 0.18345  -0.05556 0.00638  109 TRP A O   
519  C CB  . TRP A 110 ? 0.57684 0.69701 0.58973 0.14390  -0.03507 -0.00030 109 TRP A CB  
520  C CG  . TRP A 110 ? 0.65707 0.74596 0.64378 0.14607  -0.04162 -0.00391 109 TRP A CG  
521  C CD1 . TRP A 110 ? 0.65116 0.73501 0.63800 0.13391  -0.05349 -0.00634 109 TRP A CD1 
522  C CD2 . TRP A 110 ? 0.70374 0.76047 0.65882 0.16117  -0.03604 -0.00559 109 TRP A CD2 
523  N NE1 . TRP A 110 ? 0.74680 0.79836 0.70456 0.14033  -0.05573 -0.00954 109 TRP A NE1 
524  C CE2 . TRP A 110 ? 0.73660 0.77004 0.67362 0.15697  -0.04487 -0.00899 109 TRP A CE2 
525  C CE3 . TRP A 110 ? 0.73677 0.78094 0.67608 0.17785  -0.02409 -0.00457 109 TRP A CE3 
526  C CZ2 . TRP A 110 ? 0.79303 0.79033 0.69590 0.16853  -0.04161 -0.01118 109 TRP A CZ2 
527  C CZ3 . TRP A 110 ? 0.85487 0.86222 0.75991 0.18958  -0.02091 -0.00665 109 TRP A CZ3 
528  C CH2 . TRP A 110 ? 0.79148 0.77537 0.67816 0.18474  -0.02941 -0.00981 109 TRP A CH2 
529  N N   . PHE A 111 ? 0.60669 0.75849 0.62998 0.18539  -0.03030 0.00747  110 PHE A N   
530  C CA  . PHE A 111 ? 0.66341 0.80866 0.67318 0.20817  -0.02808 0.00894  110 PHE A CA  
531  C C   . PHE A 111 ? 0.68193 0.79419 0.66411 0.21400  -0.01009 0.00683  110 PHE A C   
532  O O   . PHE A 111 ? 0.66862 0.77733 0.65248 0.20224  0.00133  0.00486  110 PHE A O   
533  C CB  . PHE A 111 ? 0.63916 0.82740 0.67931 0.21801  -0.03102 0.01243  110 PHE A CB  
534  C CG  . PHE A 111 ? 0.71037 0.93586 0.78199 0.21064  -0.04690 0.01334  110 PHE A CG  
535  C CD1 . PHE A 111 ? 0.67778 0.92823 0.77655 0.19108  -0.04703 0.01395  110 PHE A CD1 
536  C CD2 . PHE A 111 ? 0.82442 1.05961 0.89777 0.22357  -0.06140 0.01318  110 PHE A CD2 
537  C CE1 . PHE A 111 ? 0.70301 0.98678 0.83057 0.18327  -0.06049 0.01417  110 PHE A CE1 
538  C CE2 . PHE A 111 ? 0.83567 1.10661 0.93920 0.21630  -0.07562 0.01276  110 PHE A CE2 
539  C CZ  . PHE A 111 ? 0.81021 1.10526 0.94120 0.19553  -0.07473 0.01317  110 PHE A CZ  
540  N N   . GLU A 112 ? 0.67624 0.76392 0.63220 0.23275  -0.00745 0.00691  111 GLU A N   
541  C CA  . GLU A 112 ? 0.75529 0.81242 0.68511 0.24079  0.01022  0.00491  111 GLU A CA  
542  C C   . GLU A 112 ? 0.70265 0.77760 0.64034 0.26037  0.01449  0.00845  111 GLU A C   
543  O O   . GLU A 112 ? 0.69763 0.78837 0.64169 0.27552  0.00320  0.01134  111 GLU A O   
544  C CB  . GLU A 112 ? 0.77273 0.78115 0.66129 0.24682  0.01305  0.00174  111 GLU A CB  
545  C CG  . GLU A 112 ? 0.82098 0.79511 0.68166 0.25207  0.03303  -0.00168 111 GLU A CG  
546  C CD  . GLU A 112 ? 0.93515 0.85894 0.75422 0.25470  0.03780  -0.00580 111 GLU A CD  
547  O OE1 . GLU A 112 ? 0.94100 0.85641 0.75209 0.25362  0.02497  -0.00547 111 GLU A OE1 
548  O OE2 . GLU A 112 ? 0.98779 0.88018 0.78196 0.25736  0.05497  -0.00980 111 GLU A OE2 
549  N N   . ARG A 113 ? 0.73445 0.80799 0.67220 0.26027  0.03046  0.00751  112 ARG A N   
550  C CA  . ARG A 113 ? 0.73536 0.82277 0.67866 0.27813  0.03716  0.01003  112 ARG A CA  
551  C C   . ARG A 113 ? 0.78762 0.83291 0.69589 0.28709  0.05440  0.00714  112 ARG A C   
552  O O   . ARG A 113 ? 0.78990 0.80168 0.67559 0.27597  0.06217  0.00249  112 ARG A O   
553  C CB  . ARG A 113 ? 0.71538 0.84430 0.69445 0.26928  0.04095  0.01156  112 ARG A CB  
554  C CG  . ARG A 113 ? 0.59696 0.77193 0.61197 0.26720  0.02549  0.01468  112 ARG A CG  
555  C CD  . ARG A 113 ? 0.62764 0.83985 0.67509 0.25698  0.03133  0.01600  112 ARG A CD  
556  N NE  . ARG A 113 ? 0.62997 0.88742 0.71155 0.25830  0.01903  0.01814  112 ARG A NE  
557  C CZ  . ARG A 113 ? 0.57883 0.87355 0.69170 0.25011  0.02210  0.01942  112 ARG A CZ  
558  N NH1 . ARG A 113 ? 0.51872 0.81156 0.63317 0.24041  0.03622  0.01949  112 ARG A NH1 
559  N NH2 . ARG A 113 ? 0.55385 0.88885 0.69682 0.25160  0.01104  0.02005  112 ARG A NH2 
560  N N   . PRO A 114 ? 0.84560 0.89082 0.74803 0.30691  0.06096  0.00898  113 PRO A N   
561  C CA  . PRO A 114 ? 0.90811 0.91063 0.77552 0.31548  0.07825  0.00596  113 PRO A CA  
562  C C   . PRO A 114 ? 0.91439 0.90280 0.77718 0.29814  0.09442  0.00045  113 PRO A C   
563  O O   . PRO A 114 ? 0.95398 0.89974 0.78435 0.29609  0.10545  -0.00455 113 PRO A O   
564  C CB  . PRO A 114 ? 0.95345 0.97264 0.82786 0.33675  0.08190  0.00911  113 PRO A CB  
565  C CG  . PRO A 114 ? 0.89940 0.95357 0.79648 0.34616  0.06269  0.01322  113 PRO A CG  
566  C CD  . PRO A 114 ? 0.83257 0.91320 0.75663 0.32411  0.05185  0.01311  113 PRO A CD  
567  N N   . ASP A 115 ? 0.88668 0.90937 0.78026 0.28549  0.09635  0.00059  114 ASP A N   
568  C CA  . ASP A 115 ? 0.89831 0.91066 0.78833 0.27135  0.11165  -0.00510 114 ASP A CA  
569  C C   . ASP A 115 ? 0.84839 0.88189 0.76056 0.24930  0.10540  -0.00632 114 ASP A C   
570  O O   . ASP A 115 ? 0.80046 0.83612 0.71705 0.23805  0.11609  -0.01043 114 ASP A O   
571  C CB  . ASP A 115 ? 0.99622 1.02373 0.89613 0.27984  0.12491  -0.00456 114 ASP A CB  
572  C CG  . ASP A 115 ? 1.07524 1.07629 0.94940 0.30121  0.13364  -0.00440 114 ASP A CG  
573  O OD1 . ASP A 115 ? 1.13227 1.08916 0.97202 0.30277  0.14161  -0.00886 114 ASP A OD1 
574  O OD2 . ASP A 115 ? 1.04821 1.07200 0.93593 0.31645  0.13274  -0.00015 114 ASP A OD2 
575  N N   . SER A 116 ? 0.80841 0.85665 0.73352 0.24328  0.08839  -0.00321 115 SER A N   
576  C CA  . SER A 116 ? 0.71971 0.78855 0.66628 0.22316  0.08197  -0.00371 115 SER A CA  
577  C C   . SER A 116 ? 0.69609 0.76542 0.64481 0.21735  0.06446  -0.00224 115 SER A C   
578  O O   . SER A 116 ? 0.67431 0.73805 0.61488 0.23009  0.05559  0.00036  115 SER A O   
579  C CB  . SER A 116 ? 0.65216 0.76546 0.63379 0.22069  0.08115  0.00100  115 SER A CB  
580  O OG  . SER A 116 ? 0.61499 0.75591 0.61547 0.23083  0.06862  0.00664  115 SER A OG  
581  N N   . PHE A 117 ? 0.64231 0.71817 0.60146 0.19846  0.05946  -0.00421 116 PHE A N   
582  C CA  . PHE A 117 ? 0.61615 0.70090 0.58507 0.18996  0.04232  -0.00252 116 PHE A CA  
583  C C   . PHE A 117 ? 0.61637 0.74259 0.62108 0.17939  0.03537  0.00177  116 PHE A C   
584  O O   . PHE A 117 ? 0.54143 0.67877 0.55669 0.17095  0.04418  0.00124  116 PHE A O   
585  C CB  . PHE A 117 ? 0.63449 0.68918 0.58367 0.17607  0.04160  -0.00909 116 PHE A CB  
586  C CG  . PHE A 117 ? 0.68563 0.70054 0.60070 0.18463  0.04382  -0.01285 116 PHE A CG  
587  C CD1 . PHE A 117 ? 0.72392 0.70764 0.61268 0.18957  0.06053  -0.01835 116 PHE A CD1 
588  C CD2 . PHE A 117 ? 0.71761 0.72557 0.62616 0.18741  0.02971  -0.01124 116 PHE A CD2 
589  C CE1 . PHE A 117 ? 0.83396 0.77860 0.68945 0.19662  0.06388  -0.02191 116 PHE A CE1 
590  C CE2 . PHE A 117 ? 0.77534 0.74462 0.65023 0.19524  0.03232  -0.01442 116 PHE A CE2 
591  C CZ  . PHE A 117 ? 0.78762 0.72436 0.63542 0.19959  0.04979  -0.01962 116 PHE A CZ  
592  N N   . VAL A 118 ? 0.51699 0.66555 0.53958 0.17990  0.02000  0.00563  117 VAL A N   
593  C CA  . VAL A 118 ? 0.50006 0.68740 0.55657 0.16910  0.01281  0.00933  117 VAL A CA  
594  C C   . VAL A 118 ? 0.55222 0.73666 0.61193 0.15378  -0.00021 0.00813  117 VAL A C   
595  O O   . VAL A 118 ? 0.52599 0.69969 0.57627 0.15807  -0.01115 0.00737  117 VAL A O   
596  C CB  . VAL A 118 ? 0.52368 0.74501 0.60279 0.18199  0.00621  0.01357  117 VAL A CB  
597  C CG1 . VAL A 118 ? 0.51049 0.77118 0.62460 0.16887  0.00030  0.01638  117 VAL A CG1 
598  C CG2 . VAL A 118 ? 0.48920 0.71202 0.56383 0.19826  0.01892  0.01435  117 VAL A CG2 
599  N N   . LEU A 119 ? 0.47444 0.66747 0.54621 0.13651  0.00093  0.00791  118 LEU A N   
600  C CA  . LEU A 119 ? 0.48041 0.66989 0.55517 0.12082  -0.01040 0.00647  118 LEU A CA  
601  C C   . LEU A 119 ? 0.48491 0.71151 0.59260 0.11130  -0.01856 0.01095  118 LEU A C   
602  O O   . LEU A 119 ? 0.43990 0.68617 0.56365 0.10655  -0.01089 0.01360  118 LEU A O   
603  C CB  . LEU A 119 ? 0.47458 0.64050 0.53386 0.10815  -0.00316 0.00156  118 LEU A CB  
604  C CG  . LEU A 119 ? 0.56616 0.69234 0.59301 0.11025  0.00038  -0.00548 118 LEU A CG  
605  C CD1 . LEU A 119 ? 0.54457 0.65474 0.55297 0.12710  0.01180  -0.00659 118 LEU A CD1 
606  C CD2 . LEU A 119 ? 0.54596 0.65676 0.56341 0.09683  0.00660  -0.01144 118 LEU A CD2 
607  N N   . ILE A 120 ? 0.43967 0.67524 0.55679 0.10810  -0.03350 0.01138  119 ILE A N   
608  C CA  . ILE A 120 ? 0.45335 0.72300 0.60152 0.09780  -0.04186 0.01443  119 ILE A CA  
609  C C   . ILE A 120 ? 0.45605 0.71535 0.60336 0.07850  -0.04683 0.01304  119 ILE A C   
610  O O   . ILE A 120 ? 0.44343 0.68566 0.57957 0.07479  -0.05684 0.01012  119 ILE A O   
611  C CB  . ILE A 120 ? 0.50406 0.79325 0.66537 0.10653  -0.05547 0.01477  119 ILE A CB  
612  C CG1 . ILE A 120 ? 0.52444 0.81983 0.68226 0.12811  -0.05120 0.01548  119 ILE A CG1 
613  C CG2 . ILE A 120 ? 0.49121 0.81771 0.68657 0.09476  -0.06243 0.01665  119 ILE A CG2 
614  C CD1 . ILE A 120 ? 0.47596 0.79648 0.65160 0.13112  -0.03966 0.01808  119 ILE A CD1 
615  N N   . LEU A 121 ? 0.36240 0.63141 0.52058 0.06664  -0.03992 0.01508  120 LEU A N   
616  C CA  . LEU A 121 ? 0.45210 0.71035 0.60808 0.04922  -0.04337 0.01398  120 LEU A CA  
617  C C   . LEU A 121 ? 0.48413 0.77160 0.66854 0.03666  -0.04938 0.01773  120 LEU A C   
618  O O   . LEU A 121 ? 0.46036 0.77684 0.66613 0.03937  -0.04555 0.02108  120 LEU A O   
619  C CB  . LEU A 121 ? 0.40715 0.64879 0.54878 0.04531  -0.03030 0.01273  120 LEU A CB  
620  C CG  . LEU A 121 ? 0.43781 0.65134 0.55214 0.05620  -0.02142 0.00783  120 LEU A CG  
621  C CD1 . LEU A 121 ? 0.46921 0.67622 0.57597 0.05383  -0.00748 0.00674  120 LEU A CD1 
622  C CD2 . LEU A 121 ? 0.43549 0.61984 0.52876 0.05304  -0.02913 0.00174  120 LEU A CD2 
623  N N   . GLU A 122 ? 0.50095 0.78035 0.68541 0.02255  -0.05841 0.01653  121 GLU A N   
624  C CA  . GLU A 122 ? 0.57534 0.87713 0.78354 0.00802  -0.06203 0.01975  121 GLU A CA  
625  C C   . GLU A 122 ? 0.58815 0.89576 0.80026 0.00223  -0.04861 0.02341  121 GLU A C   
626  O O   . GLU A 122 ? 0.65000 0.93857 0.84326 0.00594  -0.03890 0.02243  121 GLU A O   
627  C CB  . GLU A 122 ? 0.59660 0.88311 0.79977 -0.00584 -0.07309 0.01750  121 GLU A CB  
628  C CG  . GLU A 122 ? 0.66683 0.92401 0.84760 -0.01251 -0.06806 0.01547  121 GLU A CG  
629  C CD  . GLU A 122 ? 0.70797 0.95137 0.88484 -0.02614 -0.07922 0.01305  121 GLU A CD  
630  O OE1 . GLU A 122 ? 0.76313 1.02285 0.95841 -0.03373 -0.08902 0.01433  121 GLU A OE1 
631  O OE2 . GLU A 122 ? 0.63873 0.85562 0.79444 -0.02907 -0.07821 0.00909  121 GLU A OE2 
632  N N   . ARG A 123 ? 0.53755 0.87196 0.77417 -0.00705 -0.04760 0.02712  122 ARG A N   
633  C CA  . ARG A 123 ? 0.61045 0.95159 0.85152 -0.01352 -0.03476 0.03115  122 ARG A CA  
634  C C   . ARG A 123 ? 0.59034 0.93960 0.84533 -0.03206 -0.03797 0.03374  122 ARG A C   
635  O O   . ARG A 123 ? 0.54007 0.91799 0.82072 -0.03741 -0.04007 0.03499  122 ARG A O   
636  C CB  . ARG A 123 ? 0.57794 0.94626 0.83495 -0.00364 -0.02517 0.03331  122 ARG A CB  
637  C CG  . ARG A 123 ? 0.55888 0.93539 0.82089 -0.01053 -0.01134 0.03755  122 ARG A CG  
638  C CD  . ARG A 123 ? 0.56253 0.96227 0.83633 0.00138  -0.00102 0.03870  122 ARG A CD  
639  N NE  . ARG A 123 ? 0.54590 0.97840 0.84621 0.00479  -0.00705 0.03759  122 ARG A NE  
640  C CZ  . ARG A 123 ? 0.58080 1.04318 0.90734 -0.00512 -0.00460 0.03904  122 ARG A CZ  
641  N NH1 . ARG A 123 ? 0.59761 1.05963 0.92631 -0.01943 0.00428  0.04274  122 ARG A NH1 
642  N NH2 . ARG A 123 ? 0.55186 1.04503 0.90238 -0.00042 -0.01096 0.03615  122 ARG A NH2 
643  N N   . PRO A 124 ? 0.60163 0.92619 0.84012 -0.04210 -0.03833 0.03392  123 PRO A N   
644  C CA  . PRO A 124 ? 0.57191 0.90076 0.82040 -0.05951 -0.03878 0.03721  123 PRO A CA  
645  C C   . PRO A 124 ? 0.51390 0.85909 0.77256 -0.06304 -0.02445 0.04226  123 PRO A C   
646  O O   . PRO A 124 ? 0.53359 0.87756 0.78400 -0.05331 -0.01366 0.04320  123 PRO A O   
647  C CB  . PRO A 124 ? 0.61554 0.91009 0.83857 -0.06526 -0.04209 0.03550  123 PRO A CB  
648  C CG  . PRO A 124 ? 0.60344 0.87986 0.80441 -0.05135 -0.03691 0.03207  123 PRO A CG  
649  C CD  . PRO A 124 ? 0.59780 0.88896 0.80725 -0.03785 -0.03868 0.03020  123 PRO A CD  
650  N N   . GLU A 125 ? 0.50115 0.86179 0.77801 -0.07763 -0.02390 0.04514  124 GLU A N   
651  C CA  . GLU A 125 ? 0.48487 0.86186 0.77279 -0.08362 -0.01007 0.04982  124 GLU A CA  
652  C C   . GLU A 125 ? 0.52458 0.89373 0.81346 -0.10274 -0.00942 0.05309  124 GLU A C   
653  O O   . GLU A 125 ? 0.54352 0.91399 0.84148 -0.11238 -0.02004 0.05119  124 GLU A O   
654  C CB  . GLU A 125 ? 0.47209 0.88834 0.78995 -0.07996 -0.00731 0.04891  124 GLU A CB  
655  C CG  . GLU A 125 ? 0.52667 0.95231 0.84379 -0.06027 -0.00492 0.04671  124 GLU A CG  
656  C CD  . GLU A 125 ? 0.57849 0.99716 0.88240 -0.05353 0.00991  0.04973  124 GLU A CD  
657  O OE1 . GLU A 125 ? 0.64236 1.03254 0.92020 -0.04722 0.01105  0.04921  124 GLU A OE1 
658  N N   . PRO A 126 ? 0.51834 0.87776 0.79657 -0.10833 0.00294  0.05793  125 PRO A N   
659  C CA  . PRO A 126 ? 0.46024 0.81458 0.72471 -0.09797 0.01551  0.06005  125 PRO A CA  
660  C C   . PRO A 126 ? 0.48241 0.80246 0.71552 -0.09048 0.01241  0.05803  125 PRO A C   
661  O O   . PRO A 126 ? 0.45771 0.75539 0.67775 -0.09745 0.00369  0.05692  125 PRO A O   
662  C CB  . PRO A 126 ? 0.49032 0.84888 0.75814 -0.11078 0.02837  0.06592  125 PRO A CB  
663  C CG  . PRO A 126 ? 0.49670 0.83939 0.76099 -0.12685 0.02115  0.06708  125 PRO A CG  
664  C CD  . PRO A 126 ? 0.49976 0.85358 0.77998 -0.12681 0.00605  0.06184  125 PRO A CD  
665  N N   . VAL A 127 ? 0.45570 0.77128 0.67650 -0.07649 0.01938  0.05661  126 VAL A N   
666  C CA  . VAL A 127 ? 0.45221 0.73785 0.64475 -0.06908 0.01709  0.05274  126 VAL A CA  
667  C C   . VAL A 127 ? 0.45053 0.72978 0.62843 -0.06324 0.03099  0.05459  126 VAL A C   
668  O O   . VAL A 127 ? 0.40940 0.70886 0.59929 -0.06086 0.04224  0.05810  126 VAL A O   
669  C CB  . VAL A 127 ? 0.49778 0.78005 0.68653 -0.05610 0.00966  0.04629  126 VAL A CB  
670  C CG1 . VAL A 127 ? 0.46964 0.75050 0.66573 -0.06172 -0.00563 0.04364  126 VAL A CG1 
671  C CG2 . VAL A 127 ? 0.48163 0.78824 0.68518 -0.04445 0.01679  0.04661  126 VAL A CG2 
672  N N   . GLN A 128 ? 0.42838 0.67984 0.58019 -0.06081 0.02978  0.05140  127 GLN A N   
673  C CA  . GLN A 128 ? 0.39679 0.63895 0.53080 -0.05197 0.04075  0.05027  127 GLN A CA  
674  C C   . GLN A 128 ? 0.42889 0.64598 0.54022 -0.04469 0.03407  0.04166  127 GLN A C   
675  O O   . GLN A 128 ? 0.39819 0.59869 0.50143 -0.05081 0.02281  0.03890  127 GLN A O   
676  C CB  . GLN A 128 ? 0.43629 0.67108 0.56078 -0.06003 0.04887  0.05622  127 GLN A CB  
677  C CG  . GLN A 128 ? 0.39265 0.62093 0.49994 -0.05051 0.06092  0.05531  127 GLN A CG  
678  C CD  . GLN A 128 ? 0.49535 0.71253 0.58929 -0.05791 0.06793  0.06128  127 GLN A CD  
679  O OE1 . GLN A 128 ? 0.48294 0.68309 0.56758 -0.06742 0.06113  0.06310  127 GLN A OE1 
680  N NE2 . GLN A 128 ? 0.47454 0.70031 0.56638 -0.05328 0.08178  0.06440  127 GLN A NE2 
681  N N   . ASP A 129 ? 0.37893 0.59390 0.48086 -0.03205 0.04111  0.03663  128 ASP A N   
682  C CA  . ASP A 129 ? 0.39040 0.58238 0.47123 -0.02602 0.03599  0.02693  128 ASP A CA  
683  C C   . ASP A 129 ? 0.40827 0.58007 0.46752 -0.02894 0.03651  0.02512  128 ASP A C   
684  O O   . ASP A 129 ? 0.42169 0.59640 0.47911 -0.03234 0.04403  0.03144  128 ASP A O   
685  C CB  . ASP A 129 ? 0.43196 0.62619 0.50841 -0.01226 0.04391  0.02089  128 ASP A CB  
686  C CG  . ASP A 129 ? 0.39139 0.59061 0.46190 -0.00604 0.05835  0.02209  128 ASP A CG  
687  O OD1 . ASP A 129 ? 0.48098 0.66625 0.53413 -0.00683 0.06067  0.01987  128 ASP A OD1 
688  O OD2 . ASP A 129 ? 0.54114 0.75823 0.62370 0.00063  0.06718  0.02469  128 ASP A OD2 
689  N N   . LEU A 130 ? 0.39143 0.54219 0.43338 -0.02725 0.02830  0.01590  129 LEU A N   
690  C CA  . LEU A 130 ? 0.41811 0.54893 0.43914 -0.02953 0.02590  0.01303  129 LEU A CA  
691  C C   . LEU A 130 ? 0.39937 0.52830 0.40629 -0.02062 0.03798  0.01057  129 LEU A C   
692  O O   . LEU A 130 ? 0.44174 0.55948 0.43385 -0.02224 0.03913  0.01212  129 LEU A O   
693  C CB  . LEU A 130 ? 0.38432 0.49553 0.39194 -0.02942 0.01383  0.00218  129 LEU A CB  
694  C CG  . LEU A 130 ? 0.42665 0.51614 0.41184 -0.03063 0.00849  -0.00309 129 LEU A CG  
695  C CD1 . LEU A 130 ? 0.38152 0.46743 0.36741 -0.04092 0.00578  0.00739  129 LEU A CD1 
696  C CD2 . LEU A 130 ? 0.41448 0.48839 0.39067 -0.03104 -0.00385 -0.01466 129 LEU A CD2 
697  N N   . PHE A 131 ? 0.40441 0.54338 0.41469 -0.01080 0.04710  0.00672  130 PHE A N   
698  C CA  . PHE A 131 ? 0.44010 0.57972 0.43885 -0.00239 0.05921  0.00438  130 PHE A CA  
699  C C   . PHE A 131 ? 0.44849 0.59971 0.45360 -0.00651 0.06781  0.01639  130 PHE A C   
700  O O   . PHE A 131 ? 0.47162 0.61355 0.46067 -0.00559 0.07167  0.01715  130 PHE A O   
701  C CB  . PHE A 131 ? 0.40819 0.55680 0.41088 0.00827  0.06795  -0.00173 130 PHE A CB  
702  C CG  . PHE A 131 ? 0.43595 0.58631 0.42759 0.01718  0.08061  -0.00526 130 PHE A CG  
703  C CD1 . PHE A 131 ? 0.44622 0.61377 0.44763 0.01864  0.09204  0.00374  130 PHE A CD1 
704  C CD2 . PHE A 131 ? 0.45900 0.59486 0.43094 0.02391  0.08107  -0.01842 130 PHE A CD2 
705  C CE1 . PHE A 131 ? 0.49982 0.66924 0.49085 0.02689  0.10354  0.00044  130 PHE A CE1 
706  C CE2 . PHE A 131 ? 0.52236 0.66092 0.48444 0.03233  0.09238  -0.02247 130 PHE A CE2 
707  C CZ  . PHE A 131 ? 0.47381 0.62878 0.44515 0.03394  0.10355  -0.01265 130 PHE A CZ  
708  N N   . ASP A 132 ? 0.43835 0.61009 0.46628 -0.01073 0.07119  0.02528  131 ASP A N   
709  C CA  . ASP A 132 ? 0.45690 0.64103 0.49253 -0.01612 0.08025  0.03609  131 ASP A CA  
710  C C   . ASP A 132 ? 0.45569 0.62551 0.48244 -0.02744 0.07457  0.04170  131 ASP A C   
711  O O   . ASP A 132 ? 0.50646 0.67357 0.52468 -0.02992 0.08248  0.04773  131 ASP A O   
712  C CB  . ASP A 132 ? 0.44193 0.65240 0.50569 -0.01914 0.08348  0.04273  131 ASP A CB  
713  C CG  . ASP A 132 ? 0.48802 0.71329 0.55943 -0.00710 0.09197  0.03913  131 ASP A CG  
714  O OD1 . ASP A 132 ? 0.49917 0.71800 0.55581 0.00208  0.09961  0.03389  131 ASP A OD1 
715  O OD2 . ASP A 132 ? 0.54625 0.78963 0.63820 -0.00639 0.09089  0.04116  131 ASP A OD2 
716  N N   . PHE A 133 ? 0.42898 0.58848 0.45670 -0.03440 0.06119  0.03991  132 PHE A N   
717  C CA  . PHE A 133 ? 0.43304 0.57662 0.45153 -0.04524 0.05503  0.04471  132 PHE A CA  
718  C C   . PHE A 133 ? 0.47329 0.59380 0.46218 -0.03994 0.05603  0.04105  132 PHE A C   
719  O O   . PHE A 133 ? 0.46855 0.58019 0.44667 -0.04493 0.06049  0.04817  132 PHE A O   
720  C CB  . PHE A 133 ? 0.44130 0.57767 0.46540 -0.05184 0.03981  0.04140  132 PHE A CB  
721  C CG  . PHE A 133 ? 0.46644 0.58847 0.48513 -0.06438 0.03318  0.04688  132 PHE A CG  
722  C CD1 . PHE A 133 ? 0.47743 0.61283 0.51581 -0.07685 0.03469  0.05586  132 PHE A CD1 
723  C CD2 . PHE A 133 ? 0.48746 0.58274 0.48153 -0.06362 0.02538  0.04217  132 PHE A CD2 
724  C CE1 . PHE A 133 ? 0.45892 0.57964 0.49184 -0.08910 0.02945  0.06058  132 PHE A CE1 
725  C CE2 . PHE A 133 ? 0.53500 0.61496 0.52266 -0.07473 0.01939  0.04731  132 PHE A CE2 
726  C CZ  . PHE A 133 ? 0.51668 0.60856 0.52350 -0.08788 0.02181  0.05677  132 PHE A CZ  
727  N N   . ILE A 134 ? 0.44832 0.55873 0.42301 -0.02948 0.05233  0.02934  133 ILE A N   
728  C CA  . ILE A 134 ? 0.50395 0.59426 0.45071 -0.02276 0.05216  0.02363  133 ILE A CA  
729  C C   . ILE A 134 ? 0.51614 0.61324 0.45595 -0.01608 0.06677  0.02736  133 ILE A C   
730  O O   . ILE A 134 ? 0.54420 0.62673 0.46318 -0.01455 0.06902  0.02956  133 ILE A O   
731  C CB  . ILE A 134 ? 0.44529 0.52604 0.38123 -0.01394 0.04480  0.00817  133 ILE A CB  
732  C CG1 . ILE A 134 ? 0.42653 0.49640 0.36474 -0.02130 0.02957  0.00466  133 ILE A CG1 
733  C CG2 . ILE A 134 ? 0.50456 0.56989 0.41354 -0.00441 0.04618  0.00012  133 ILE A CG2 
734  C CD1 . ILE A 134 ? 0.43407 0.49760 0.36626 -0.01461 0.02301  -0.01069 133 ILE A CD1 
735  N N   . THR A 135 ? 0.51405 0.63264 0.47011 -0.01148 0.07686  0.02815  134 THR A N   
736  C CA  . THR A 135 ? 0.49315 0.62025 0.44464 -0.00563 0.09122  0.03197  134 THR A CA  
737  C C   . THR A 135 ? 0.53568 0.66217 0.48683 -0.01539 0.09691  0.04531  134 THR A C   
738  O O   . THR A 135 ? 0.55589 0.67379 0.48856 -0.01185 0.10419  0.04793  134 THR A O   
739  C CB  . THR A 135 ? 0.45427 0.60561 0.42604 -0.00015 0.10056  0.03131  134 THR A CB  
740  O OG1 . THR A 135 ? 0.45046 0.59889 0.41852 0.00922  0.09731  0.01841  134 THR A OG1 
741  C CG2 . THR A 135 ? 0.54846 0.71008 0.51706 0.00514  0.11570  0.03568  134 THR A CG2 
742  N N   . GLU A 136 ? 0.51700 0.65183 0.48751 -0.02788 0.09393  0.05332  135 GLU A N   
743  C CA  . GLU A 136 ? 0.57980 0.71605 0.55256 -0.03875 0.10139  0.06544  135 GLU A CA  
744  C C   . GLU A 136 ? 0.56421 0.67190 0.51355 -0.04501 0.09481  0.06839  135 GLU A C   
745  O O   . GLU A 136 ? 0.54502 0.64341 0.48059 -0.04856 0.10315  0.07610  135 GLU A O   
746  C CB  . GLU A 136 ? 0.53793 0.69675 0.54209 -0.04992 0.10170  0.07154  135 GLU A CB  
747  C CG  . GLU A 136 ? 0.63515 0.82311 0.66190 -0.04363 0.11023  0.07059  135 GLU A CG  
748  C CD  . GLU A 136 ? 0.69194 0.90359 0.74979 -0.05325 0.10916  0.07513  135 GLU A CD  
749  O OE1 . GLU A 136 ? 0.71448 0.92100 0.77716 -0.06621 0.10340  0.07953  135 GLU A OE1 
750  O OE2 . GLU A 136 ? 0.74622 0.98179 0.82354 -0.04744 0.11395  0.07370  135 GLU A OE2 
751  N N   . ARG A 137 ? 0.55378 0.64605 0.49701 -0.04628 0.08022  0.06240  136 ARG A N   
752  C CA  . ARG A 137 ? 0.59147 0.65620 0.51332 -0.05234 0.07305  0.06518  136 ARG A CA  
753  C C   . ARG A 137 ? 0.57270 0.61406 0.46214 -0.03992 0.06897  0.05719  136 ARG A C   
754  O O   . ARG A 137 ? 0.61289 0.62949 0.47940 -0.04232 0.06530  0.06032  136 ARG A O   
755  C CB  . ARG A 137 ? 0.60398 0.66473 0.53756 -0.06182 0.05892  0.06347  136 ARG A CB  
756  C CG  . ARG A 137 ? 0.69411 0.78163 0.66201 -0.07137 0.06053  0.06793  136 ARG A CG  
757  C CD  . ARG A 137 ? 0.75375 0.83998 0.73051 -0.08810 0.06210  0.07808  136 ARG A CD  
758  N NE  . ARG A 137 ? 0.78241 0.84461 0.74680 -0.09465 0.04913  0.07675  136 ARG A NE  
759  C CZ  . ARG A 137 ? 0.70764 0.77242 0.68780 -0.10850 0.04324  0.08019  136 ARG A CZ  
760  N NH1 . ARG A 137 ? 0.61871 0.71047 0.62877 -0.11719 0.04833  0.08437  136 ARG A NH1 
761  N NH2 . ARG A 137 ? 0.68291 0.72353 0.64895 -0.11338 0.03168  0.07857  136 ARG A NH2 
762  N N   . GLY A 138 ? 0.58423 0.63265 0.47064 -0.02652 0.06989  0.04655  137 GLY A N   
763  C CA  . GLY A 138 ? 0.59490 0.62407 0.45303 -0.01441 0.06460  0.03618  137 GLY A CA  
764  C C   . GLY A 138 ? 0.60864 0.62432 0.46248 -0.01491 0.04820  0.02634  137 GLY A C   
765  O O   . GLY A 138 ? 0.54709 0.57156 0.42143 -0.02218 0.04167  0.02553  137 GLY A O   
766  N N   . ALA A 139 ? 0.60126 0.59555 0.42749 -0.00652 0.04126  0.01828  138 ALA A N   
767  C CA  . ALA A 139 ? 0.57040 0.55020 0.38990 -0.00673 0.02542  0.00825  138 ALA A CA  
768  C C   . ALA A 139 ? 0.58960 0.56007 0.41646 -0.02153 0.01794  0.01796  138 ALA A C   
769  O O   . ALA A 139 ? 0.58182 0.54199 0.40103 -0.02842 0.02239  0.03018  138 ALA A O   
770  C CB  . ALA A 139 ? 0.57491 0.53349 0.36211 0.00536  0.01964  -0.00151 138 ALA A CB  
771  N N   . LEU A 140 ? 0.50381 0.47742 0.34509 -0.02677 0.00713  0.01217  139 LEU A N   
772  C CA  . LEU A 140 ? 0.52866 0.49671 0.38056 -0.04113 -0.00034 0.02007  139 LEU A CA  
773  C C   . LEU A 140 ? 0.54203 0.48142 0.36974 -0.04126 -0.01256 0.01679  139 LEU A C   
774  O O   . LEU A 140 ? 0.57677 0.50536 0.38725 -0.03076 -0.02037 0.00371  139 LEU A O   
775  C CB  . LEU A 140 ? 0.47983 0.46410 0.35754 -0.04624 -0.00684 0.01540  139 LEU A CB  
776  C CG  . LEU A 140 ? 0.49223 0.50387 0.39319 -0.04400 0.00308  0.01628  139 LEU A CG  
777  C CD1 . LEU A 140 ? 0.45751 0.48047 0.37984 -0.04862 -0.00506 0.01190  139 LEU A CD1 
778  C CD2 . LEU A 140 ? 0.52085 0.54608 0.43433 -0.05061 0.01585  0.03057  139 LEU A CD2 
779  N N   . GLN A 141 ? 0.54280 0.47007 0.36936 -0.05324 -0.01395 0.02807  140 GLN A N   
780  C CA  . GLN A 141 ? 0.61925 0.51951 0.42656 -0.05535 -0.02687 0.02554  140 GLN A CA  
781  C C   . GLN A 141 ? 0.57233 0.47511 0.38871 -0.05488 -0.04126 0.01274  140 GLN A C   
782  O O   . GLN A 141 ? 0.54338 0.46667 0.38603 -0.06029 -0.04183 0.01159  140 GLN A O   
783  C CB  . GLN A 141 ? 0.61146 0.50197 0.42292 -0.07124 -0.02538 0.03950  140 GLN A CB  
784  C CG  . GLN A 141 ? 0.78184 0.66994 0.58587 -0.07430 -0.00978 0.05269  140 GLN A CG  
785  C CD  . GLN A 141 ? 0.86449 0.74123 0.67164 -0.09122 -0.00757 0.06511  140 GLN A CD  
786  O OE1 . GLN A 141 ? 0.83982 0.70892 0.65316 -0.10005 -0.01858 0.06378  140 GLN A OE1 
787  N NE2 . GLN A 141 ? 0.91468 0.79025 0.71761 -0.09638 0.00729  0.07676  140 GLN A NE2 
788  N N   . GLU A 142 ? 0.49825 0.40588 0.40173 0.02239  -0.00447 0.01665  141 GLU A N   
789  C CA  . GLU A 142 ? 0.54308 0.45723 0.45275 0.02906  -0.00728 0.00997  141 GLU A CA  
790  C C   . GLU A 142 ? 0.53417 0.43066 0.44224 0.02156  -0.00763 0.00789  141 GLU A C   
791  O O   . GLU A 142 ? 0.54393 0.45125 0.46233 0.02096  -0.00877 0.00200  141 GLU A O   
792  C CB  . GLU A 142 ? 0.54807 0.45876 0.44629 0.04630  -0.00983 0.01086  141 GLU A CB  
793  C CG  . GLU A 142 ? 0.56444 0.49918 0.46596 0.05298  -0.01125 0.01196  141 GLU A CG  
794  C CD  . GLU A 142 ? 0.60145 0.54386 0.49796 0.07047  -0.01466 0.01256  141 GLU A CD  
795  O OE1 . GLU A 142 ? 0.55161 0.48561 0.44604 0.07849  -0.01495 0.01024  141 GLU A OE1 
796  O OE2 . GLU A 142 ? 0.59876 0.55716 0.49313 0.07657  -0.01698 0.01553  141 GLU A OE2 
797  N N   . GLU A 143 ? 0.54361 0.41273 0.43758 0.01454  -0.00681 0.01273  142 GLU A N   
798  C CA  . GLU A 143 ? 0.58619 0.43878 0.47718 0.00401  -0.00791 0.01049  142 GLU A CA  
799  C C   . GLU A 143 ? 0.55947 0.43569 0.47177 -0.00889 -0.00784 0.00851  142 GLU A C   
800  O O   . GLU A 143 ? 0.53169 0.41006 0.44882 -0.01261 -0.01003 0.00376  142 GLU A O   
801  C CB  . GLU A 143 ? 0.62915 0.44894 0.50103 -0.00472 -0.00701 0.01664  142 GLU A CB  
802  C CG  . GLU A 143 ? 0.70769 0.50701 0.57225 -0.01755 -0.00906 0.01394  142 GLU A CG  
803  C CD  . GLU A 143 ? 0.73136 0.49931 0.57772 -0.03044 -0.00814 0.02029  142 GLU A CD  
804  O OE1 . GLU A 143 ? 0.72338 0.50313 0.57908 -0.04330 -0.00630 0.02642  142 GLU A OE1 
805  O OE2 . GLU A 143 ? 0.79156 0.52220 0.61343 -0.02774 -0.00861 0.01924  142 GLU A OE2 
806  N N   . LEU A 144 ? 0.53981 0.43377 0.46402 -0.01475 -0.00492 0.01248  143 LEU A N   
807  C CA  . LEU A 144 ? 0.52143 0.43848 0.46627 -0.02426 -0.00387 0.01181  143 LEU A CA  
808  C C   . LEU A 144 ? 0.51659 0.45524 0.47479 -0.01672 -0.00434 0.00549  143 LEU A C   
809  O O   . LEU A 144 ? 0.47816 0.42722 0.44795 -0.02149 -0.00555 0.00300  143 LEU A O   
810  C CB  . LEU A 144 ? 0.52656 0.45497 0.47857 -0.03041 0.00102  0.01797  143 LEU A CB  
811  C CG  . LEU A 144 ? 0.55373 0.50699 0.52739 -0.03750 0.00375  0.01879  143 LEU A CG  
812  C CD1 . LEU A 144 ? 0.49207 0.44430 0.47143 -0.04909 0.00022  0.02001  143 LEU A CD1 
813  C CD2 . LEU A 144 ? 0.53975 0.50256 0.51772 -0.04124 0.01019  0.02502  143 LEU A CD2 
814  N N   . ALA A 145 ? 0.49846 0.44460 0.45465 -0.00584 -0.00367 0.00335  144 ALA A N   
815  C CA  . ALA A 145 ? 0.47667 0.44230 0.44408 -0.00049 -0.00418 -0.00263 144 ALA A CA  
816  C C   . ALA A 145 ? 0.49698 0.45807 0.46234 0.00320  -0.00740 -0.00718 144 ALA A C   
817  O O   . ALA A 145 ? 0.43555 0.41094 0.41242 0.00194  -0.00756 -0.01100 144 ALA A O   
818  C CB  . ALA A 145 ? 0.42319 0.39844 0.38712 0.00865  -0.00395 -0.00384 144 ALA A CB  
819  N N   . ARG A 146 ? 0.51071 0.45022 0.45985 0.00812  -0.00925 -0.00671 145 ARG A N   
820  C CA  . ARG A 146 ? 0.52090 0.45333 0.46509 0.01223  -0.01114 -0.01145 145 ARG A CA  
821  C C   . ARG A 146 ? 0.50115 0.43304 0.45125 -0.00003 -0.01239 -0.01259 145 ARG A C   
822  O O   . ARG A 146 ? 0.49168 0.43393 0.44813 0.00070  -0.01314 -0.01681 145 ARG A O   
823  C CB  . ARG A 146 ? 0.51073 0.41449 0.43302 0.02032  -0.01171 -0.01054 145 ARG A CB  
824  C CG  . ARG A 146 ? 0.57657 0.46742 0.48941 0.02441  -0.01247 -0.01594 145 ARG A CG  
825  C CD  . ARG A 146 ? 0.59028 0.44753 0.47837 0.03400  -0.01176 -0.01523 145 ARG A CD  
826  N NE  . ARG A 146 ? 0.63888 0.50142 0.52398 0.05047  -0.01066 -0.01225 145 ARG A NE  
827  C CZ  . ARG A 146 ? 0.66693 0.51593 0.54196 0.05310  -0.01033 -0.00583 145 ARG A CZ  
828  N NH1 . ARG A 146 ? 0.60932 0.43618 0.47523 0.04015  -0.01021 -0.00178 145 ARG A NH1 
829  N NH2 . ARG A 146 ? 0.58730 0.44683 0.46135 0.06859  -0.01029 -0.00274 145 ARG A NH2 
830  N N   . SER A 147 ? 0.51373 0.43552 0.46195 -0.01192 -0.01282 -0.00815 146 SER A N   
831  C CA  . SER A 147 ? 0.49355 0.41811 0.44789 -0.02444 -0.01517 -0.00804 146 SER A CA  
832  C C   . SER A 147 ? 0.51470 0.46772 0.49063 -0.02626 -0.01405 -0.00795 146 SER A C   
833  O O   . SER A 147 ? 0.50579 0.46600 0.48669 -0.02884 -0.01611 -0.01034 146 SER A O   
834  C CB  . SER A 147 ? 0.52307 0.43604 0.47325 -0.03784 -0.01586 -0.00214 146 SER A CB  
835  O OG  . SER A 147 ? 0.53280 0.45686 0.49333 -0.05065 -0.01868 -0.00056 146 SER A OG  
836  N N   . PHE A 148 ? 0.41683 0.38418 0.40366 -0.02458 -0.01037 -0.00514 147 PHE A N   
837  C CA  . PHE A 148 ? 0.44064 0.43025 0.44524 -0.02490 -0.00806 -0.00520 147 PHE A CA  
838  C C   . PHE A 148 ? 0.45054 0.44757 0.45690 -0.01761 -0.00849 -0.01106 147 PHE A C   
839  O O   . PHE A 148 ? 0.39272 0.39954 0.40782 -0.02010 -0.00900 -0.01174 147 PHE A O   
840  C CB  . PHE A 148 ? 0.41113 0.40969 0.42191 -0.02312 -0.00305 -0.00259 147 PHE A CB  
841  C CG  . PHE A 148 ? 0.46551 0.46584 0.48124 -0.03126 -0.00074 0.00430  147 PHE A CG  
842  C CD1 . PHE A 148 ? 0.45767 0.45237 0.47240 -0.04108 -0.00411 0.00808  147 PHE A CD1 
843  C CD2 . PHE A 148 ? 0.46195 0.47079 0.48286 -0.02980 0.00511  0.00691  147 PHE A CD2 
844  C CE1 . PHE A 148 ? 0.50615 0.50694 0.52754 -0.04974 -0.00185 0.01524  147 PHE A CE1 
845  C CE2 . PHE A 148 ? 0.44975 0.46347 0.47645 -0.03667 0.00843  0.01384  147 PHE A CE2 
846  C CZ  . PHE A 148 ? 0.45521 0.46657 0.48347 -0.04687 0.00488  0.01847  147 PHE A CZ  
847  N N   . PHE A 149 ? 0.41113 0.40547 0.40965 -0.00860 -0.00822 -0.01447 148 PHE A N   
848  C CA  . PHE A 149 ? 0.41142 0.41686 0.41307 -0.00247 -0.00819 -0.01943 148 PHE A CA  
849  C C   . PHE A 149 ? 0.42127 0.42172 0.41860 -0.00285 -0.01047 -0.02197 148 PHE A C   
850  O O   . PHE A 149 ? 0.43530 0.44771 0.43999 -0.00333 -0.00989 -0.02410 148 PHE A O   
851  C CB  . PHE A 149 ? 0.41425 0.42078 0.40864 0.00747  -0.00826 -0.02137 148 PHE A CB  
852  C CG  . PHE A 149 ? 0.37902 0.40394 0.38021 0.01189  -0.00775 -0.02557 148 PHE A CG  
853  C CD1 . PHE A 149 ? 0.39904 0.43840 0.41151 0.00674  -0.00562 -0.02673 148 PHE A CD1 
854  C CD2 . PHE A 149 ? 0.37392 0.40137 0.36961 0.02110  -0.00882 -0.02811 148 PHE A CD2 
855  C CE1 . PHE A 149 ? 0.38906 0.44481 0.40705 0.00815  -0.00523 -0.03041 148 PHE A CE1 
856  C CE2 . PHE A 149 ? 0.35943 0.40770 0.36302 0.02372  -0.00819 -0.03124 148 PHE A CE2 
857  C CZ  . PHE A 149 ? 0.35546 0.41781 0.37013 0.01597  -0.00674 -0.03241 148 PHE A CZ  
858  N N   . TRP A 150 ? 0.43781 0.41858 0.42111 -0.00328 -0.01272 -0.02185 149 TRP A N   
859  C CA  . TRP A 150 ? 0.43430 0.40703 0.40946 -0.00426 -0.01469 -0.02509 149 TRP A CA  
860  C C   . TRP A 150 ? 0.45600 0.43894 0.44143 -0.01440 -0.01631 -0.02321 149 TRP A C   
861  O O   . TRP A 150 ? 0.40685 0.39662 0.39327 -0.01370 -0.01653 -0.02577 149 TRP A O   
862  C CB  . TRP A 150 ? 0.46247 0.40720 0.41776 -0.00524 -0.01662 -0.02548 149 TRP A CB  
863  C CG  . TRP A 150 ? 0.53838 0.47036 0.48043 -0.00641 -0.01834 -0.03001 149 TRP A CG  
864  C CD1 . TRP A 150 ? 0.50750 0.43538 0.44704 -0.01876 -0.02201 -0.02973 149 TRP A CD1 
865  C CD2 . TRP A 150 ? 0.48364 0.40619 0.41200 0.00552  -0.01627 -0.03546 149 TRP A CD2 
866  N NE1 . TRP A 150 ? 0.53276 0.44688 0.45564 -0.01614 -0.02248 -0.03546 149 TRP A NE1 
867  C CE2 . TRP A 150 ? 0.56355 0.47368 0.47940 -0.00059 -0.01827 -0.03914 149 TRP A CE2 
868  C CE3 . TRP A 150 ? 0.50452 0.42995 0.43014 0.02127  -0.01284 -0.03722 149 TRP A CE3 
869  C CZ2 . TRP A 150 ? 0.51879 0.41664 0.41801 0.00909  -0.01575 -0.04518 149 TRP A CZ2 
870  C CZ3 . TRP A 150 ? 0.54774 0.46394 0.45955 0.03177  -0.01035 -0.04228 149 TRP A CZ3 
871  C CH2 . TRP A 150 ? 0.51379 0.41506 0.41185 0.02593  -0.01123 -0.04656 149 TRP A CH2 
872  N N   . GLN A 151 ? 0.42798 0.41387 0.42145 -0.02324 -0.01715 -0.01789 150 GLN A N   
873  C CA  . GLN A 151 ? 0.42131 0.41947 0.42572 -0.03141 -0.01902 -0.01445 150 GLN A CA  
874  C C   . GLN A 151 ? 0.44052 0.45702 0.45904 -0.02744 -0.01574 -0.01424 150 GLN A C   
875  O O   . GLN A 151 ? 0.42891 0.45327 0.45182 -0.03011 -0.01707 -0.01310 150 GLN A O   
876  C CB  . GLN A 151 ? 0.42455 0.42579 0.43649 -0.04047 -0.01994 -0.00777 150 GLN A CB  
877  C CG  . GLN A 151 ? 0.45629 0.43916 0.45405 -0.04916 -0.02406 -0.00714 150 GLN A CG  
878  C CD  . GLN A 151 ? 0.47113 0.46343 0.47950 -0.06033 -0.02517 0.00052  150 GLN A CD  
879  O OE1 . GLN A 151 ? 0.45384 0.46725 0.47890 -0.06321 -0.02539 0.00541  150 GLN A OE1 
880  N NE2 . GLN A 151 ? 0.53808 0.51547 0.53699 -0.06615 -0.02538 0.00238  150 GLN A NE2 
881  N N   . VAL A 152 ? 0.39546 0.41754 0.41942 -0.02187 -0.01155 -0.01515 151 VAL A N   
882  C CA  . VAL A 152 ? 0.37894 0.41407 0.41296 -0.01949 -0.00813 -0.01594 151 VAL A CA  
883  C C   . VAL A 152 ? 0.37042 0.40795 0.39960 -0.01629 -0.00865 -0.02042 151 VAL A C   
884  O O   . VAL A 152 ? 0.38994 0.43539 0.42487 -0.01802 -0.00756 -0.01953 151 VAL A O   
885  C CB  . VAL A 152 ? 0.41795 0.45655 0.45511 -0.01587 -0.00409 -0.01724 151 VAL A CB  
886  C CG1 . VAL A 152 ? 0.38177 0.42991 0.42555 -0.01508 -0.00070 -0.01946 151 VAL A CG1 
887  C CG2 . VAL A 152 ? 0.36587 0.40399 0.40838 -0.01876 -0.00191 -0.01235 151 VAL A CG2 
888  N N   . LEU A 153 ? 0.39603 0.42662 0.41405 -0.01086 -0.00967 -0.02461 152 LEU A N   
889  C CA  . LEU A 153 ? 0.41342 0.44813 0.42670 -0.00661 -0.00910 -0.02864 152 LEU A CA  
890  C C   . LEU A 153 ? 0.40414 0.43529 0.41279 -0.01143 -0.01138 -0.02789 152 LEU A C   
891  O O   . LEU A 153 ? 0.40900 0.44934 0.42001 -0.01167 -0.00986 -0.02851 152 LEU A O   
892  C CB  . LEU A 153 ? 0.42152 0.44851 0.42302 0.00244  -0.00914 -0.03238 152 LEU A CB  
893  C CG  . LEU A 153 ? 0.50238 0.53803 0.50806 0.00845  -0.00757 -0.03295 152 LEU A CG  
894  C CD1 . LEU A 153 ? 0.54363 0.56630 0.53627 0.01768  -0.00845 -0.03383 152 LEU A CD1 
895  C CD2 . LEU A 153 ? 0.54952 0.60591 0.56354 0.01068  -0.00515 -0.03536 152 LEU A CD2 
896  N N   . GLU A 154 ? 0.38922 0.40741 0.39023 -0.01649 -0.01526 -0.02629 153 GLU A N   
897  C CA  . GLU A 154 ? 0.42839 0.44435 0.42362 -0.02265 -0.01868 -0.02546 153 GLU A CA  
898  C C   . GLU A 154 ? 0.45797 0.48934 0.46768 -0.02746 -0.01868 -0.01967 153 GLU A C   
899  O O   . GLU A 154 ? 0.38377 0.42020 0.39131 -0.02898 -0.01932 -0.01912 153 GLU A O   
900  C CB  . GLU A 154 ? 0.44073 0.44062 0.42492 -0.02981 -0.02363 -0.02476 153 GLU A CB  
901  C CG  . GLU A 154 ? 0.48048 0.45836 0.44526 -0.02465 -0.02325 -0.03051 153 GLU A CG  
902  C CD  . GLU A 154 ? 0.50191 0.47052 0.44959 -0.02146 -0.02308 -0.03639 153 GLU A CD  
903  O OE1 . GLU A 154 ? 0.53611 0.50700 0.48023 -0.02929 -0.02655 -0.03570 153 GLU A OE1 
904  O OE2 . GLU A 154 ? 0.51358 0.47367 0.45097 -0.01044 -0.01928 -0.04131 153 GLU A OE2 
905  N N   . ALA A 155 ? 0.37364 0.41172 0.39700 -0.02881 -0.01723 -0.01498 154 ALA A N   
906  C CA  . ALA A 155 ? 0.38014 0.43041 0.41660 -0.03091 -0.01606 -0.00884 154 ALA A CA  
907  C C   . ALA A 155 ? 0.41077 0.46696 0.44984 -0.02724 -0.01158 -0.01059 154 ALA A C   
908  O O   . ALA A 155 ? 0.39254 0.45407 0.43380 -0.02899 -0.01171 -0.00677 154 ALA A O   
909  C CB  . ALA A 155 ? 0.40268 0.45712 0.45147 -0.03101 -0.01361 -0.00426 154 ALA A CB  
910  N N   . VAL A 156 ? 0.35052 0.40665 0.38898 -0.02290 -0.00787 -0.01572 155 VAL A N   
911  C CA  . VAL A 156 ? 0.35553 0.41874 0.39678 -0.02184 -0.00367 -0.01745 155 VAL A CA  
912  C C   . VAL A 156 ? 0.41416 0.47969 0.44689 -0.02155 -0.00434 -0.01951 155 VAL A C   
913  O O   . VAL A 156 ? 0.43478 0.50592 0.46940 -0.02368 -0.00190 -0.01746 155 VAL A O   
914  C CB  . VAL A 156 ? 0.38978 0.45597 0.43269 -0.01874 -0.00073 -0.02225 155 VAL A CB  
915  C CG1 . VAL A 156 ? 0.38106 0.45650 0.42645 -0.02016 0.00302  -0.02433 155 VAL A CG1 
916  C CG2 . VAL A 156 ? 0.42598 0.48911 0.47524 -0.01941 0.00094  -0.02032 155 VAL A CG2 
917  N N   . ARG A 157 ? 0.39857 0.45795 0.42004 -0.01871 -0.00688 -0.02350 156 ARG A N   
918  C CA  . ARG A 157 ? 0.44642 0.50606 0.45704 -0.01782 -0.00686 -0.02578 156 ARG A CA  
919  C C   . ARG A 157 ? 0.42960 0.48964 0.43883 -0.02394 -0.00966 -0.02039 156 ARG A C   
920  O O   . ARG A 157 ? 0.42737 0.49307 0.43310 -0.02475 -0.00764 -0.01958 156 ARG A O   
921  C CB  . ARG A 157 ? 0.44933 0.49633 0.44485 -0.01340 -0.00886 -0.03100 156 ARG A CB  
922  C CG  . ARG A 157 ? 0.43252 0.48157 0.42659 -0.00417 -0.00545 -0.03587 156 ARG A CG  
923  C CD  . ARG A 157 ? 0.47316 0.50438 0.44933 0.00154  -0.00669 -0.04036 156 ARG A CD  
924  N NE  . ARG A 157 ? 0.47264 0.49861 0.43444 0.00150  -0.00616 -0.04313 156 ARG A NE  
925  C CZ  . ARG A 157 ? 0.51102 0.51640 0.45261 0.00393  -0.00734 -0.04754 156 ARG A CZ  
926  N NH1 . ARG A 157 ? 0.45084 0.43747 0.38422 0.00621  -0.00924 -0.04904 156 ARG A NH1 
927  N NH2 . ARG A 157 ? 0.50209 0.50342 0.42921 0.00364  -0.00623 -0.05058 156 ARG A NH2 
928  N N   . HIS A 158 ? 0.41769 0.47384 0.42993 -0.02837 -0.01435 -0.01584 157 HIS A N   
929  C CA  . HIS A 158 ? 0.43024 0.49047 0.44276 -0.03365 -0.01810 -0.00921 157 HIS A CA  
930  C C   . HIS A 158 ? 0.44257 0.51147 0.46554 -0.03310 -0.01392 -0.00344 157 HIS A C   
931  O O   . HIS A 158 ? 0.41418 0.48663 0.43254 -0.03494 -0.01441 0.00028  157 HIS A O   
932  C CB  . HIS A 158 ? 0.46281 0.52249 0.48040 -0.03845 -0.02370 -0.00441 157 HIS A CB  
933  C CG  . HIS A 158 ? 0.51668 0.58584 0.53857 -0.04291 -0.02810 0.00434  157 HIS A CG  
934  N ND1 . HIS A 158 ? 0.49512 0.56410 0.50390 -0.04814 -0.03395 0.00482  157 HIS A ND1 
935  C CD2 . HIS A 158 ? 0.53241 0.61190 0.56945 -0.04200 -0.02746 0.01339  157 HIS A CD2 
936  C CE1 . HIS A 158 ? 0.52101 0.60222 0.53779 -0.05066 -0.03766 0.01451  157 HIS A CE1 
937  N NE2 . HIS A 158 ? 0.51238 0.60004 0.54689 -0.04610 -0.03345 0.02016  157 HIS A NE2 
938  N N   . CYS A 159 ? 0.40346 0.47357 0.43824 -0.03085 -0.00951 -0.00266 158 CYS A N   
939  C CA  . CYS A 159 ? 0.37584 0.44860 0.41761 -0.03073 -0.00454 0.00194  158 CYS A CA  
940  C C   . CYS A 159 ? 0.41688 0.49239 0.45189 -0.03171 -0.00087 -0.00089 158 CYS A C   
941  O O   . CYS A 159 ? 0.40003 0.47674 0.43322 -0.03367 0.00052  0.00466  158 CYS A O   
942  C CB  . CYS A 159 ? 0.37967 0.44974 0.43081 -0.02885 0.00013  0.00063  158 CYS A CB  
943  S SG  . CYS A 159 ? 0.40562 0.47489 0.46676 -0.02700 -0.00144 0.00589  158 CYS A SG  
944  N N   . HIS A 160 ? 0.37828 0.45623 0.40982 -0.02995 0.00108  -0.00865 159 HIS A N   
945  C CA  . HIS A 160 ? 0.43994 0.52507 0.46731 -0.03089 0.00543  -0.01102 159 HIS A CA  
946  C C   . HIS A 160 ? 0.40497 0.49086 0.42036 -0.03152 0.00368  -0.00945 159 HIS A C   
947  O O   . HIS A 160 ? 0.43253 0.52323 0.44507 -0.03428 0.00733  -0.00659 159 HIS A O   
948  C CB  . HIS A 160 ? 0.42383 0.51554 0.45152 -0.02714 0.00744  -0.01872 159 HIS A CB  
949  C CG  . HIS A 160 ? 0.45461 0.54811 0.49214 -0.02813 0.00944  -0.02039 159 HIS A CG  
950  N ND1 . HIS A 160 ? 0.50102 0.60579 0.54146 -0.02680 0.01171  -0.02546 159 HIS A ND1 
951  C CD2 . HIS A 160 ? 0.45354 0.53965 0.49760 -0.03021 0.00961  -0.01768 159 HIS A CD2 
952  C CE1 . HIS A 160 ? 0.48001 0.58337 0.52697 -0.02939 0.01240  -0.02627 159 HIS A CE1 
953  N NE2 . HIS A 160 ? 0.45262 0.54324 0.50110 -0.03113 0.01179  -0.02197 159 HIS A NE2 
954  N N   . ASN A 161 ? 0.41681 0.49675 0.42336 -0.03013 -0.00182 -0.01119 160 ASN A N   
955  C CA  . ASN A 161 ? 0.49724 0.57595 0.48924 -0.03180 -0.00424 -0.01028 160 ASN A CA  
956  C C   . ASN A 161 ? 0.49665 0.57746 0.49035 -0.03625 -0.00630 -0.00054 160 ASN A C   
957  O O   . ASN A 161 ? 0.47021 0.55319 0.45271 -0.03817 -0.00620 0.00178  160 ASN A O   
958  C CB  . ASN A 161 ? 0.52679 0.59536 0.50710 -0.03164 -0.01040 -0.01449 160 ASN A CB  
959  C CG  . ASN A 161 ? 0.59648 0.65967 0.56887 -0.02525 -0.00759 -0.02368 160 ASN A CG  
960  O OD1 . ASN A 161 ? 0.67771 0.74859 0.64968 -0.02052 -0.00136 -0.02701 160 ASN A OD1 
961  N ND2 . ASN A 161 ? 0.60438 0.65479 0.57038 -0.02490 -0.01194 -0.02713 160 ASN A ND2 
962  N N   . CYS A 162 ? 0.44846 0.52872 0.45507 -0.03688 -0.00781 0.00573  161 CYS A N   
963  C CA  . CYS A 162 ? 0.45484 0.53714 0.46455 -0.03852 -0.00909 0.01642  161 CYS A CA  
964  C C   . CYS A 162 ? 0.44262 0.52373 0.45753 -0.03860 -0.00145 0.02022  161 CYS A C   
965  O O   . CYS A 162 ? 0.45648 0.53580 0.47395 -0.03837 -0.00111 0.02988  161 CYS A O   
966  C CB  . CYS A 162 ? 0.45070 0.53392 0.47170 -0.03760 -0.01382 0.02229  161 CYS A CB  
967  S SG  . CYS A 162 ? 0.51364 0.59836 0.52825 -0.04135 -0.02372 0.01973  161 CYS A SG  
968  N N   . GLY A 163 ? 0.43223 0.51419 0.44827 -0.03919 0.00455  0.01332  162 GLY A N   
969  C CA  . GLY A 163 ? 0.41467 0.49457 0.43403 -0.04224 0.01168  0.01606  162 GLY A CA  
970  C C   . GLY A 163 ? 0.46755 0.53895 0.49758 -0.04166 0.01455  0.01754  162 GLY A C   
971  O O   . GLY A 163 ? 0.41233 0.47596 0.44266 -0.04458 0.01990  0.02209  162 GLY A O   
972  N N   . VAL A 164 ? 0.41019 0.48080 0.44704 -0.03825 0.01182  0.01366  163 VAL A N   
973  C CA  . VAL A 164 ? 0.40016 0.46207 0.44541 -0.03647 0.01473  0.01504  163 VAL A CA  
974  C C   . VAL A 164 ? 0.43009 0.49360 0.47848 -0.03738 0.01641  0.00553  163 VAL A C   
975  O O   . VAL A 164 ? 0.36347 0.43372 0.41116 -0.03541 0.01259  0.00003  163 VAL A O   
976  C CB  . VAL A 164 ? 0.44455 0.50631 0.49579 -0.03126 0.01031  0.02113  163 VAL A CB  
977  C CG1 . VAL A 164 ? 0.40088 0.45455 0.46010 -0.02794 0.01461  0.02120  163 VAL A CG1 
978  C CG2 . VAL A 164 ? 0.41848 0.48100 0.46758 -0.02981 0.00824  0.03214  163 VAL A CG2 
979  N N   . LEU A 165 ? 0.45161 0.50744 0.50174 -0.04049 0.02198  0.00382  164 LEU A N   
980  C CA  . LEU A 165 ? 0.45308 0.51037 0.50556 -0.04201 0.02320  -0.00435 164 LEU A CA  
981  C C   . LEU A 165 ? 0.41520 0.46020 0.47106 -0.03864 0.02548  -0.00307 164 LEU A C   
982  O O   . LEU A 165 ? 0.43681 0.46798 0.49121 -0.03914 0.03053  0.00114  164 LEU A O   
983  C CB  . LEU A 165 ? 0.46205 0.52158 0.51195 -0.05051 0.02758  -0.00840 164 LEU A CB  
984  C CG  . LEU A 165 ? 0.47301 0.53941 0.52470 -0.05367 0.02757  -0.01685 164 LEU A CG  
985  C CD1 . LEU A 165 ? 0.43932 0.52348 0.49284 -0.04898 0.02288  -0.02107 164 LEU A CD1 
986  C CD2 . LEU A 165 ? 0.45070 0.51769 0.49996 -0.06496 0.03204  -0.01924 164 LEU A CD2 
987  N N   . HIS A 166 ? 0.42704 0.47570 0.48612 -0.03465 0.02260  -0.00640 165 HIS A N   
988  C CA  . HIS A 166 ? 0.39462 0.43413 0.45712 -0.03030 0.02527  -0.00446 165 HIS A CA  
989  C C   . HIS A 166 ? 0.42438 0.45216 0.48259 -0.03394 0.03137  -0.00965 165 HIS A C   
990  O O   . HIS A 166 ? 0.44312 0.45620 0.50026 -0.03128 0.03706  -0.00659 165 HIS A O   
991  C CB  . HIS A 166 ? 0.41913 0.46585 0.48491 -0.02648 0.02084  -0.00615 165 HIS A CB  
992  C CG  . HIS A 166 ? 0.41910 0.46035 0.48956 -0.02164 0.02393  -0.00292 165 HIS A CG  
993  N ND1 . HIS A 166 ? 0.39202 0.42518 0.45974 -0.02144 0.02896  -0.00761 165 HIS A ND1 
994  C CD2 . HIS A 166 ? 0.43511 0.47981 0.51279 -0.01690 0.02299  0.00477  165 HIS A CD2 
995  C CE1 . HIS A 166 ? 0.41568 0.44654 0.48837 -0.01571 0.03203  -0.00308 165 HIS A CE1 
996  N NE2 . HIS A 166 ? 0.41872 0.45813 0.49891 -0.01288 0.02842  0.00488  165 HIS A NE2 
997  N N   . ARG A 167 ? 0.39689 0.43109 0.45181 -0.03966 0.03025  -0.01753 166 ARG A N   
998  C CA  . ARG A 167 ? 0.43682 0.46265 0.48562 -0.04644 0.03439  -0.02390 166 ARG A CA  
999  C C   . ARG A 167 ? 0.47751 0.49309 0.52364 -0.04285 0.03729  -0.02665 166 ARG A C   
1000 O O   . ARG A 167 ? 0.49570 0.50023 0.53373 -0.04878 0.04126  -0.03229 166 ARG A O   
1001 C CB  . ARG A 167 ? 0.42918 0.43946 0.47232 -0.05287 0.04022  -0.02182 166 ARG A CB  
1002 C CG  . ARG A 167 ? 0.45363 0.47435 0.49749 -0.05871 0.03865  -0.01965 166 ARG A CG  
1003 C CD  . ARG A 167 ? 0.51624 0.52286 0.55224 -0.06973 0.04436  -0.02024 166 ARG A CD  
1004 N NE  . ARG A 167 ? 0.51351 0.49438 0.54419 -0.06593 0.05044  -0.01382 166 ARG A NE  
1005 C CZ  . ARG A 167 ? 0.58235 0.54332 0.60365 -0.07394 0.05647  -0.01227 166 ARG A CZ  
1006 N NH1 . ARG A 167 ? 0.59166 0.55723 0.60866 -0.08844 0.05704  -0.01680 166 ARG A NH1 
1007 N NH2 . ARG A 167 ? 0.54261 0.47876 0.55865 -0.06723 0.06232  -0.00538 166 ARG A NH2 
1008 N N   . ASP A 168 ? 0.40323 0.42198 0.45464 -0.03445 0.03572  -0.02309 167 ASP A N   
1009 C CA  . ASP A 168 ? 0.41414 0.42565 0.46268 -0.03096 0.03913  -0.02556 167 ASP A CA  
1010 C C   . ASP A 168 ? 0.37587 0.39981 0.42973 -0.02578 0.03421  -0.02390 167 ASP A C   
1011 O O   . ASP A 168 ? 0.40963 0.43131 0.46683 -0.02004 0.03678  -0.02008 167 ASP A O   
1012 C CB  . ASP A 168 ? 0.43997 0.43441 0.48799 -0.02530 0.04710  -0.02076 167 ASP A CB  
1013 C CG  . ASP A 168 ? 0.52942 0.51167 0.56957 -0.02339 0.05335  -0.02565 167 ASP A CG  
1014 O OD1 . ASP A 168 ? 0.48366 0.46916 0.51679 -0.02881 0.05111  -0.03336 167 ASP A OD1 
1015 O OD2 . ASP A 168 ? 0.56151 0.53171 0.60193 -0.01569 0.06073  -0.02143 167 ASP A OD2 
1016 N N   . ILE A 169 ? 0.37278 0.40960 0.42695 -0.02767 0.02765  -0.02641 168 ILE A N   
1017 C CA  . ILE A 169 ? 0.35070 0.39477 0.40648 -0.02361 0.02318  -0.02533 168 ILE A CA  
1018 C C   . ILE A 169 ? 0.39428 0.43507 0.44424 -0.02299 0.02532  -0.02920 168 ILE A C   
1019 O O   . ILE A 169 ? 0.38631 0.42872 0.42968 -0.02688 0.02492  -0.03538 168 ILE A O   
1020 C CB  . ILE A 169 ? 0.37177 0.42672 0.42656 -0.02401 0.01689  -0.02740 168 ILE A CB  
1021 C CG1 . ILE A 169 ? 0.37099 0.42865 0.42900 -0.02489 0.01537  -0.02397 168 ILE A CG1 
1022 C CG2 . ILE A 169 ? 0.34801 0.40472 0.40129 -0.01981 0.01287  -0.02621 168 ILE A CG2 
1023 C CD1 . ILE A 169 ? 0.32668 0.39452 0.38210 -0.02473 0.01136  -0.02706 168 ILE A CD1 
1024 N N   . LYS A 170 ? 0.38286 0.42077 0.43502 -0.01880 0.02757  -0.02520 169 LYS A N   
1025 C CA  . LYS A 170 ? 0.39536 0.43037 0.44081 -0.01769 0.03004  -0.02785 169 LYS A CA  
1026 C C   . LYS A 170 ? 0.39587 0.43263 0.44672 -0.01367 0.03116  -0.02121 169 LYS A C   
1027 O O   . LYS A 170 ? 0.38521 0.42551 0.44553 -0.01236 0.03048  -0.01490 169 LYS A O   
1028 C CB  . LYS A 170 ? 0.39996 0.42343 0.43812 -0.01927 0.03742  -0.03237 169 LYS A CB  
1029 C CG  . LYS A 170 ? 0.43009 0.44390 0.47318 -0.01537 0.04491  -0.02781 169 LYS A CG  
1030 C CD  . LYS A 170 ? 0.45810 0.45507 0.48943 -0.01633 0.05320  -0.03358 169 LYS A CD  
1031 C CE  . LYS A 170 ? 0.49900 0.48376 0.53398 -0.00983 0.06183  -0.02848 169 LYS A CE  
1032 N NZ  . LYS A 170 ? 0.51666 0.47954 0.53650 -0.01005 0.07117  -0.03497 169 LYS A NZ  
1033 N N   . ASP A 171 ? 0.37570 0.41142 0.42013 -0.01261 0.03266  -0.02219 170 ASP A N   
1034 C CA  . ASP A 171 ? 0.38394 0.42280 0.43322 -0.01060 0.03382  -0.01545 170 ASP A CA  
1035 C C   . ASP A 171 ? 0.37958 0.41923 0.43837 -0.00718 0.04128  -0.00999 170 ASP A C   
1036 O O   . ASP A 171 ? 0.37251 0.42047 0.44148 -0.00679 0.04064  -0.00244 170 ASP A O   
1037 C CB  . ASP A 171 ? 0.37618 0.41310 0.41502 -0.01026 0.03474  -0.01688 170 ASP A CB  
1038 C CG  . ASP A 171 ? 0.42827 0.45865 0.45681 -0.00958 0.04124  -0.02269 170 ASP A CG  
1039 O OD1 . ASP A 171 ? 0.37930 0.40382 0.40826 -0.00934 0.04614  -0.02572 170 ASP A OD1 
1040 O OD2 . ASP A 171 ? 0.44473 0.47396 0.46248 -0.00959 0.04145  -0.02427 170 ASP A OD2 
1041 N N   . GLU A 172 ? 0.36541 0.39659 0.42077 -0.00474 0.04832  -0.01339 171 GLU A N   
1042 C CA  . GLU A 172 ? 0.43738 0.46808 0.50125 0.00140  0.05651  -0.00769 171 GLU A CA  
1043 C C   . GLU A 172 ? 0.40009 0.43885 0.47752 0.00234  0.05275  -0.00054 171 GLU A C   
1044 O O   . GLU A 172 ? 0.40076 0.44730 0.48978 0.00784  0.05691  0.00760  171 GLU A O   
1045 C CB  . GLU A 172 ? 0.41347 0.42739 0.46697 0.00396  0.06501  -0.01372 171 GLU A CB  
1046 C CG  . GLU A 172 ? 0.46859 0.47332 0.50546 0.00189  0.06854  -0.02192 171 GLU A CG  
1047 C CD  . GLU A 172 ? 0.49393 0.47846 0.51816 0.00328  0.07745  -0.02838 171 GLU A CD  
1048 O OE1 . GLU A 172 ? 0.55268 0.53056 0.57980 0.01182  0.08733  -0.02446 171 GLU A OE1 
1049 O OE2 . GLU A 172 ? 0.54097 0.51627 0.55223 -0.00421 0.07467  -0.03710 171 GLU A OE2 
1050 N N   . ASN A 173 ? 0.39927 0.43806 0.47538 -0.00246 0.04514  -0.00295 172 ASN A N   
1051 C CA  . ASN A 173 ? 0.40450 0.44992 0.49031 -0.00222 0.04119  0.00332  172 ASN A CA  
1052 C C   . ASN A 173 ? 0.38248 0.43946 0.47271 -0.00684 0.03207  0.00659  172 ASN A C   
1053 O O   . ASN A 173 ? 0.41004 0.47028 0.50209 -0.00933 0.02632  0.00820  172 ASN A O   
1054 C CB  . ASN A 173 ? 0.37133 0.40755 0.45124 -0.00453 0.04046  -0.00099 172 ASN A CB  
1055 C CG  . ASN A 173 ? 0.42334 0.44446 0.49854 -0.00053 0.04988  -0.00241 172 ASN A CG  
1056 O OD1 . ASN A 173 ? 0.43855 0.45810 0.51826 0.00687  0.05704  0.00240  172 ASN A OD1 
1057 N ND2 . ASN A 173 ? 0.40143 0.41095 0.46694 -0.00547 0.05046  -0.00889 172 ASN A ND2 
1058 N N   . ILE A 174 ? 0.39295 0.45427 0.48304 -0.00853 0.03110  0.00765  173 ILE A N   
1059 C CA  . ILE A 174 ? 0.39155 0.45913 0.48280 -0.01412 0.02318  0.01041  173 ILE A CA  
1060 C C   . ILE A 174 ? 0.41603 0.49439 0.51652 -0.01499 0.02547  0.01811  173 ILE A C   
1061 O O   . ILE A 174 ? 0.37479 0.45146 0.47274 -0.01313 0.03128  0.01760  173 ILE A O   
1062 C CB  . ILE A 174 ? 0.38242 0.44133 0.46050 -0.01692 0.01887  0.00349  173 ILE A CB  
1063 C CG1 . ILE A 174 ? 0.40508 0.45929 0.47695 -0.01659 0.01609  -0.00288 173 ILE A CG1 
1064 C CG2 . ILE A 174 ? 0.40308 0.46273 0.47926 -0.02244 0.01247  0.00650  173 ILE A CG2 
1065 C CD1 . ILE A 174 ? 0.38105 0.42993 0.44142 -0.01639 0.01341  -0.00944 173 ILE A CD1 
1066 N N   . LEU A 175 ? 0.37167 0.46277 0.48257 -0.01850 0.02089  0.02552  174 LEU A N   
1067 C CA  . LEU A 175 ? 0.41315 0.51932 0.53489 -0.02181 0.02173  0.03386  174 LEU A CA  
1068 C C   . LEU A 175 ? 0.41261 0.51561 0.52722 -0.03265 0.01383  0.03343  174 LEU A C   
1069 O O   . LEU A 175 ? 0.44099 0.53652 0.54758 -0.03722 0.00614  0.02988  174 LEU A O   
1070 C CB  . LEU A 175 ? 0.40458 0.53045 0.54336 -0.01977 0.02113  0.04357  174 LEU A CB  
1071 C CG  . LEU A 175 ? 0.41616 0.54620 0.56391 -0.00742 0.03104  0.04722  174 LEU A CG  
1072 C CD1 . LEU A 175 ? 0.42090 0.57474 0.58709 -0.00478 0.02948  0.05921  174 LEU A CD1 
1073 C CD2 . LEU A 175 ? 0.44093 0.56899 0.58781 -0.00252 0.04146  0.04626  174 LEU A CD2 
1074 N N   . ILE A 176 ? 0.39015 0.49710 0.50612 -0.03676 0.01652  0.03710  175 ILE A N   
1075 C CA  . ILE A 176 ? 0.41173 0.51240 0.51941 -0.04808 0.01024  0.03769  175 ILE A CA  
1076 C C   . ILE A 176 ? 0.48686 0.60943 0.60968 -0.05714 0.00782  0.04781  175 ILE A C   
1077 O O   . ILE A 176 ? 0.48956 0.62963 0.62582 -0.05514 0.01479  0.05483  175 ILE A O   
1078 C CB  . ILE A 176 ? 0.44986 0.53737 0.54558 -0.04788 0.01468  0.03518  175 ILE A CB  
1079 C CG1 . ILE A 176 ? 0.42646 0.49779 0.50910 -0.03894 0.01660  0.02599  175 ILE A CG1 
1080 C CG2 . ILE A 176 ? 0.42258 0.49859 0.50716 -0.05954 0.00861  0.03630  175 ILE A CG2 
1081 C CD1 . ILE A 176 ? 0.43768 0.50137 0.51073 -0.03614 0.02249  0.02475  175 ILE A CD1 
1082 N N   . ASP A 177 ? 0.43563 0.55865 0.55596 -0.06735 -0.00187 0.04858  176 ASP A N   
1083 C CA  . ASP A 177 ? 0.46822 0.61132 0.59990 -0.08029 -0.00635 0.05761  176 ASP A CA  
1084 C C   . ASP A 177 ? 0.51937 0.64980 0.64014 -0.09106 -0.00593 0.05778  176 ASP A C   
1085 O O   . ASP A 177 ? 0.56545 0.67161 0.66682 -0.09880 -0.01185 0.05211  176 ASP A O   
1086 C CB  . ASP A 177 ? 0.48889 0.63446 0.61788 -0.08896 -0.01746 0.05739  176 ASP A CB  
1087 C CG  . ASP A 177 ? 0.49634 0.66807 0.63898 -0.10362 -0.02336 0.06736  176 ASP A CG  
1088 O OD1 . ASP A 177 ? 0.52388 0.69991 0.66867 -0.11361 -0.02159 0.07166  176 ASP A OD1 
1089 O OD2 . ASP A 177 ? 0.54244 0.73180 0.69348 -0.10593 -0.03011 0.07144  176 ASP A OD2 
1090 N N   . LEU A 178 ? 0.49147 0.63717 0.62356 -0.09101 0.00189  0.06472  177 LEU A N   
1091 C CA  . LEU A 178 ? 0.53106 0.66320 0.65163 -0.09940 0.00449  0.06556  177 LEU A CA  
1092 C C   . LEU A 178 ? 0.57399 0.70322 0.68900 -0.11990 -0.00395 0.06907  177 LEU A C   
1093 O O   . LEU A 178 ? 0.62619 0.73144 0.72320 -0.12773 -0.00413 0.06734  177 LEU A O   
1094 C CB  . LEU A 178 ? 0.53769 0.68996 0.67230 -0.09453 0.01586  0.07285  177 LEU A CB  
1095 C CG  . LEU A 178 ? 0.58115 0.72975 0.71539 -0.07586 0.02552  0.06820  177 LEU A CG  
1096 C CD1 . LEU A 178 ? 0.48850 0.65911 0.63682 -0.07103 0.03746  0.07584  177 LEU A CD1 
1097 C CD2 . LEU A 178 ? 0.49698 0.61314 0.60686 -0.07166 0.02551  0.05873  177 LEU A CD2 
1098 N N   . ASN A 179 ? 0.54755 0.69945 0.67601 -0.12928 -0.01111 0.07419  178 ASN A N   
1099 C CA  . ASN A 179 ? 0.58221 0.73116 0.70378 -0.15149 -0.02000 0.07685  178 ASN A CA  
1100 C C   . ASN A 179 ? 0.60538 0.72277 0.70281 -0.15644 -0.02958 0.06694  178 ASN A C   
1101 O O   . ASN A 179 ? 0.60595 0.69715 0.68294 -0.17071 -0.03381 0.06414  178 ASN A O   
1102 C CB  . ASN A 179 ? 0.60095 0.79316 0.74839 -0.16145 -0.02414 0.08789  178 ASN A CB  
1103 C CG  . ASN A 179 ? 0.63762 0.85994 0.80577 -0.16395 -0.01535 0.09915  178 ASN A CG  
1104 O OD1 . ASN A 179 ? 0.65675 0.86454 0.81685 -0.16147 -0.00679 0.09861  178 ASN A OD1 
1105 N ND2 . ASN A 179 ? 0.68160 0.94787 0.87650 -0.16853 -0.01730 0.11010  178 ASN A ND2 
1106 N N   . ARG A 180 ? 0.51661 0.63429 0.61445 -0.14484 -0.03232 0.06167  179 ARG A N   
1107 C CA  . ARG A 180 ? 0.56663 0.65621 0.64151 -0.14766 -0.04005 0.05211  179 ARG A CA  
1108 C C   . ARG A 180 ? 0.59122 0.64703 0.64603 -0.13377 -0.03545 0.04222  179 ARG A C   
1109 O O   . ARG A 180 ? 0.57273 0.60069 0.60522 -0.13559 -0.04014 0.03416  179 ARG A O   
1110 C CB  . ARG A 180 ? 0.54674 0.65534 0.63116 -0.14371 -0.04576 0.05232  179 ARG A CB  
1111 C CG  . ARG A 180 ? 0.53970 0.68458 0.64354 -0.15720 -0.05232 0.06274  179 ARG A CG  
1112 C CD  . ARG A 180 ? 0.53293 0.69628 0.64511 -0.15117 -0.05778 0.06412  179 ARG A CD  
1113 N NE  . ARG A 180 ? 0.68908 0.82656 0.77633 -0.15626 -0.06560 0.05455  179 ARG A NE  
1114 N N   . GLY A 181 ? 0.53994 0.59830 0.60138 -0.11993 -0.02641 0.04269  180 GLY A N   
1115 C CA  . GLY A 181 ? 0.56043 0.59271 0.60519 -0.10669 -0.02290 0.03425  180 GLY A CA  
1116 C C   . GLY A 181 ? 0.58112 0.61195 0.62415 -0.09534 -0.02463 0.02734  180 GLY A C   
1117 O O   . GLY A 181 ? 0.55357 0.56175 0.57959 -0.08789 -0.02464 0.01966  180 GLY A O   
1118 N N   . GLU A 182 ? 0.50821 0.56358 0.56858 -0.09338 -0.02573 0.03070  181 GLU A N   
1119 C CA  . GLU A 182 ? 0.55834 0.61400 0.61778 -0.08413 -0.02702 0.02557  181 GLU A CA  
1120 C C   . GLU A 182 ? 0.47790 0.54632 0.55120 -0.07049 -0.01926 0.02646  181 GLU A C   
1121 O O   . GLU A 182 ? 0.46242 0.54945 0.55223 -0.06911 -0.01451 0.03343  181 GLU A O   
1122 C CB  . GLU A 182 ? 0.47181 0.54250 0.53702 -0.09212 -0.03453 0.02903  181 GLU A CB  
1123 C CG  . GLU A 182 ? 0.57955 0.63637 0.62841 -0.10789 -0.04293 0.02715  181 GLU A CG  
1124 C CD  . GLU A 182 ? 0.61435 0.69149 0.67042 -0.11799 -0.05125 0.03211  181 GLU A CD  
1125 O OE1 . GLU A 182 ? 0.62806 0.73078 0.70305 -0.11113 -0.05016 0.03818  181 GLU A OE1 
1126 O OE2 . GLU A 182 ? 0.72304 0.78941 0.76433 -0.13289 -0.05899 0.03007  181 GLU A OE2 
1127 N N   . LEU A 183 ? 0.44922 0.50740 0.51502 -0.06079 -0.01759 0.01933  182 LEU A N   
1128 C CA  . LEU A 183 ? 0.41650 0.48212 0.49136 -0.04975 -0.01080 0.01855  182 LEU A CA  
1129 C C   . LEU A 183 ? 0.46816 0.54429 0.55053 -0.04697 -0.01233 0.02001  182 LEU A C   
1130 O O   . LEU A 183 ? 0.44981 0.52219 0.52460 -0.05066 -0.01836 0.01786  182 LEU A O   
1131 C CB  . LEU A 183 ? 0.36247 0.41259 0.42486 -0.04228 -0.00800 0.01041  182 LEU A CB  
1132 C CG  . LEU A 183 ? 0.47549 0.52043 0.53474 -0.03978 -0.00297 0.01035  182 LEU A CG  
1133 C CD1 . LEU A 183 ? 0.49645 0.53453 0.54995 -0.04844 -0.00536 0.01426  182 LEU A CD1 
1134 C CD2 . LEU A 183 ? 0.47331 0.50695 0.52071 -0.03234 -0.00194 0.00292  182 LEU A CD2 
1135 N N   . LYS A 184 ? 0.43104 0.51838 0.52641 -0.04003 -0.00624 0.02381  183 LYS A N   
1136 C CA  . LYS A 184 ? 0.43923 0.53478 0.54150 -0.03607 -0.00640 0.02679  183 LYS A CA  
1137 C C   . LYS A 184 ? 0.39976 0.48867 0.50184 -0.02699 0.00132  0.02295  183 LYS A C   
1138 O O   . LYS A 184 ? 0.37587 0.46470 0.48223 -0.02235 0.00845  0.02345  183 LYS A O   
1139 C CB  . LYS A 184 ? 0.46401 0.58086 0.58328 -0.03678 -0.00691 0.03791  183 LYS A CB  
1140 C CG  . LYS A 184 ? 0.55193 0.67886 0.67182 -0.04836 -0.01631 0.04232  183 LYS A CG  
1141 C CD  . LYS A 184 ? 0.60139 0.75040 0.73506 -0.04768 -0.01980 0.05239  183 LYS A CD  
1142 C CE  . LYS A 184 ? 0.69955 0.86332 0.83569 -0.06132 -0.02955 0.05769  183 LYS A CE  
1143 N NZ  . LYS A 184 ? 0.71174 0.85623 0.82668 -0.07171 -0.03713 0.04900  183 LYS A NZ  
1144 N N   . LEU A 185 ? 0.39941 0.48231 0.49520 -0.02547 0.00015  0.01902  184 LEU A N   
1145 C CA  . LEU A 185 ? 0.39356 0.46982 0.48841 -0.01958 0.00679  0.01579  184 LEU A CA  
1146 C C   . LEU A 185 ? 0.43126 0.51394 0.53689 -0.01439 0.01093  0.02398  184 LEU A C   
1147 O O   . LEU A 185 ? 0.40630 0.49862 0.51707 -0.01541 0.00638  0.03086  184 LEU A O   
1148 C CB  . LEU A 185 ? 0.38360 0.45325 0.46833 -0.02114 0.00426  0.00954  184 LEU A CB  
1149 C CG  . LEU A 185 ? 0.43655 0.49894 0.51767 -0.01874 0.00988  0.00460  184 LEU A CG  
1150 C CD1 . LEU A 185 ? 0.43308 0.49009 0.51027 -0.01769 0.01355  -0.00157 184 LEU A CD1 
1151 C CD2 . LEU A 185 ? 0.47820 0.53994 0.55166 -0.02136 0.00671  0.00046  184 LEU A CD2 
1152 N N   . ILE A 186 ? 0.36068 0.43725 0.46834 -0.00828 0.01963  0.02348  185 ILE A N   
1153 C CA  . ILE A 186 ? 0.41035 0.48978 0.52708 -0.00059 0.02545  0.03159  185 ILE A CA  
1154 C C   . ILE A 186 ? 0.40861 0.46975 0.51712 0.00310  0.03296  0.02690  185 ILE A C   
1155 O O   . ILE A 186 ? 0.41284 0.46312 0.51061 -0.00137 0.03330  0.01754  185 ILE A O   
1156 C CB  . ILE A 186 ? 0.41420 0.50380 0.54189 0.00465  0.03077  0.03743  185 ILE A CB  
1157 C CG1 . ILE A 186 ? 0.38673 0.46419 0.50649 0.00593  0.03797  0.02950  185 ILE A CG1 
1158 C CG2 . ILE A 186 ? 0.40204 0.51074 0.53825 -0.00166 0.02312  0.04288  185 ILE A CG2 
1159 C CD1 . ILE A 186 ? 0.40569 0.49114 0.53441 0.01285  0.04611  0.03494  185 ILE A CD1 
1160 N N   . ASP A 187 ? 0.38172 0.43978 0.49520 0.01129  0.03901  0.03413  186 ASP A N   
1161 C CA  . ASP A 187 ? 0.38954 0.42604 0.49397 0.01506  0.04752  0.03109  186 ASP A CA  
1162 C C   . ASP A 187 ? 0.48453 0.51099 0.57825 0.00714  0.04421  0.02553  186 ASP A C   
1163 O O   . ASP A 187 ? 0.43339 0.45142 0.51749 0.00055  0.04462  0.01546  186 ASP A O   
1164 C CB  . ASP A 187 ? 0.48316 0.50675 0.58029 0.01656  0.05561  0.02314  186 ASP A CB  
1165 C CG  . ASP A 187 ? 0.55747 0.55628 0.64459 0.02158  0.06595  0.02126  186 ASP A CG  
1166 O OD1 . ASP A 187 ? 0.54937 0.54101 0.63648 0.02492  0.06721  0.02748  186 ASP A OD1 
1167 O OD2 . ASP A 187 ? 0.63132 0.61585 0.70857 0.02179  0.07287  0.01360  186 ASP A OD2 
1168 N N   . PHE A 188 ? 0.38197 0.41131 0.47748 0.00776  0.04105  0.03278  187 PHE A N   
1169 C CA  . PHE A 188 ? 0.46055 0.48103 0.54632 0.00095  0.03957  0.02956  187 PHE A CA  
1170 C C   . PHE A 188 ? 0.48227 0.47929 0.55972 0.00347  0.04863  0.03062  187 PHE A C   
1171 O O   . PHE A 188 ? 0.47485 0.46450 0.54542 -0.00125 0.04837  0.03183  187 PHE A O   
1172 C CB  . PHE A 188 ? 0.41158 0.44621 0.50053 -0.00067 0.03148  0.03676  187 PHE A CB  
1173 C CG  . PHE A 188 ? 0.41586 0.46630 0.50619 -0.00662 0.02259  0.03258  187 PHE A CG  
1174 C CD1 . PHE A 188 ? 0.40790 0.47151 0.50706 -0.00491 0.01894  0.03520  187 PHE A CD1 
1175 C CD2 . PHE A 188 ? 0.41246 0.46359 0.49435 -0.01388 0.01863  0.02621  187 PHE A CD2 
1176 C CE1 . PHE A 188 ? 0.42008 0.49282 0.51737 -0.01109 0.01130  0.03111  187 PHE A CE1 
1177 C CE2 . PHE A 188 ? 0.40049 0.46160 0.48091 -0.01781 0.01156  0.02206  187 PHE A CE2 
1178 C CZ  . PHE A 188 ? 0.43346 0.50317 0.52045 -0.01678 0.00777  0.02431  187 PHE A CZ  
1179 N N   . GLY A 189 ? 0.46750 0.45081 0.54366 0.01048  0.05731  0.03004  188 GLY A N   
1180 C CA  . GLY A 189 ? 0.53743 0.49304 0.60301 0.01391  0.06704  0.03111  188 GLY A CA  
1181 C C   . GLY A 189 ? 0.54897 0.48571 0.59921 0.00144  0.06951  0.02033  188 GLY A C   
1182 O O   . GLY A 189 ? 0.58640 0.49693 0.62510 0.00119  0.07703  0.02105  188 GLY A O   
1183 N N   . SER A 190 ? 0.50485 0.45419 0.55436 -0.00895 0.06350  0.01092  189 SER A N   
1184 C CA  . SER A 190 ? 0.52756 0.46677 0.56526 -0.02215 0.06428  0.00135  189 SER A CA  
1185 C C   . SER A 190 ? 0.51366 0.46987 0.55389 -0.03080 0.05692  0.00134  189 SER A C   
1186 O O   . SER A 190 ? 0.53395 0.48973 0.56766 -0.04238 0.05646  -0.00588 189 SER A O   
1187 C CB  . SER A 190 ? 0.59362 0.53474 0.62722 -0.02656 0.06412  -0.00969 189 SER A CB  
1188 O OG  . SER A 190 ? 0.67172 0.59634 0.70067 -0.01866 0.07206  -0.01056 189 SER A OG  
1189 N N   . GLY A 191 ? 0.45879 0.43114 0.50787 -0.02576 0.05132  0.00922  190 GLY A N   
1190 C CA  . GLY A 191 ? 0.49453 0.48357 0.54472 -0.03226 0.04485  0.00850  190 GLY A CA  
1191 C C   . GLY A 191 ? 0.53468 0.51458 0.57774 -0.03829 0.04770  0.01260  190 GLY A C   
1192 O O   . GLY A 191 ? 0.55092 0.50840 0.58680 -0.03836 0.05467  0.01597  190 GLY A O   
1193 N N   . ALA A 192 ? 0.49219 0.48842 0.53579 -0.04320 0.04284  0.01246  191 ALA A N   
1194 C CA  . ALA A 192 ? 0.51015 0.50182 0.54695 -0.04978 0.04530  0.01689  191 ALA A CA  
1195 C C   . ALA A 192 ? 0.51411 0.52660 0.55281 -0.04954 0.03910  0.01903  191 ALA A C   
1196 O O   . ALA A 192 ? 0.48130 0.50945 0.52503 -0.04624 0.03332  0.01489  191 ALA A O   
1197 C CB  . ALA A 192 ? 0.46949 0.45539 0.49989 -0.06285 0.04974  0.00948  191 ALA A CB  
1198 N N   . LEU A 193 ? 0.51725 0.52728 0.54962 -0.05312 0.04088  0.02563  192 LEU A N   
1199 C CA  . LEU A 193 ? 0.48066 0.50897 0.51117 -0.05458 0.03659  0.02616  192 LEU A CA  
1200 C C   . LEU A 193 ? 0.47954 0.52345 0.51170 -0.06102 0.03653  0.01580  192 LEU A C   
1201 O O   . LEU A 193 ? 0.49008 0.53087 0.52207 -0.06914 0.04091  0.01108  192 LEU A O   
1202 C CB  . LEU A 193 ? 0.54344 0.56537 0.56504 -0.05821 0.03981  0.03541  192 LEU A CB  
1203 C CG  . LEU A 193 ? 0.57954 0.58759 0.59893 -0.05033 0.03973  0.04786  192 LEU A CG  
1204 C CD1 . LEU A 193 ? 0.62813 0.62792 0.63646 -0.05468 0.04355  0.05738  192 LEU A CD1 
1205 C CD2 . LEU A 193 ? 0.53909 0.56121 0.56369 -0.04149 0.03124  0.05113  192 LEU A CD2 
1206 N N   . LEU A 194 ? 0.48036 0.54104 0.51353 -0.05723 0.03146  0.01232  193 LEU A N   
1207 C CA  . LEU A 194 ? 0.47260 0.55012 0.50782 -0.06020 0.03163  0.00368  193 LEU A CA  
1208 C C   . LEU A 194 ? 0.49625 0.58264 0.52707 -0.06818 0.03653  0.00524  193 LEU A C   
1209 O O   . LEU A 194 ? 0.51337 0.59936 0.53706 -0.06795 0.03709  0.01146  193 LEU A O   
1210 C CB  . LEU A 194 ? 0.51389 0.60208 0.54876 -0.05234 0.02589  -0.00021 193 LEU A CB  
1211 C CG  . LEU A 194 ? 0.53505 0.64065 0.57169 -0.05139 0.02617  -0.00829 193 LEU A CG  
1212 C CD1 . LEU A 194 ? 0.46245 0.57051 0.50669 -0.05355 0.02673  -0.01381 193 LEU A CD1 
1213 C CD2 . LEU A 194 ? 0.53760 0.64618 0.56961 -0.04278 0.02130  -0.01138 193 LEU A CD2 
1214 N N   . LYS A 195 ? 0.47280 0.56874 0.50765 -0.07608 0.03998  0.00008  194 LYS A N   
1215 C CA  . LYS A 195 ? 0.52388 0.63345 0.55685 -0.08505 0.04510  0.00127  194 LYS A CA  
1216 C C   . LYS A 195 ? 0.49706 0.63271 0.53812 -0.08605 0.04490  -0.00657 194 LYS A C   
1217 O O   . LYS A 195 ? 0.46670 0.60556 0.51354 -0.08164 0.04109  -0.01247 194 LYS A O   
1218 C CB  . LYS A 195 ? 0.53608 0.62982 0.56524 -0.09786 0.05085  0.00573  194 LYS A CB  
1219 C CG  . LYS A 195 ? 0.53178 0.61846 0.56483 -0.10518 0.05147  -0.00021 194 LYS A CG  
1220 C CD  . LYS A 195 ? 0.55867 0.62250 0.58375 -0.11817 0.05764  0.00399  194 LYS A CD  
1221 C CE  . LYS A 195 ? 0.56822 0.62349 0.59382 -0.12727 0.05828  -0.00337 194 LYS A CE  
1222 N NZ  . LYS A 195 ? 0.60280 0.63050 0.61723 -0.14108 0.06488  -0.00022 194 LYS A NZ  
1223 N N   . ASP A 196 ? 0.44800 0.60397 0.48953 -0.09127 0.04932  -0.00575 195 ASP A N   
1224 C CA  . ASP A 196 ? 0.45139 0.63752 0.50216 -0.09096 0.04982  -0.01157 195 ASP A CA  
1225 C C   . ASP A 196 ? 0.49603 0.69352 0.55371 -0.10686 0.05274  -0.01287 195 ASP A C   
1226 O O   . ASP A 196 ? 0.48405 0.71012 0.55165 -0.10758 0.05223  -0.01715 195 ASP A O   
1227 C CB  . ASP A 196 ? 0.49545 0.70212 0.54364 -0.08548 0.05360  -0.01028 195 ASP A CB  
1228 C CG  . ASP A 196 ? 0.54348 0.73965 0.58260 -0.07073 0.05007  -0.01097 195 ASP A CG  
1229 O OD1 . ASP A 196 ? 0.53499 0.72114 0.57516 -0.06237 0.04422  -0.01481 195 ASP A OD1 
1230 O OD2 . ASP A 196 ? 0.59491 0.79220 0.62446 -0.06860 0.05315  -0.00767 195 ASP A OD2 
1231 N N   . THR A 197 ? 0.49275 0.66832 0.54465 -0.11962 0.05565  -0.00907 196 THR A N   
1232 C CA  . THR A 197 ? 0.51822 0.69882 0.57323 -0.13770 0.05825  -0.01081 196 THR A CA  
1233 C C   . THR A 197 ? 0.57066 0.73528 0.62578 -0.13928 0.05394  -0.01675 196 THR A C   
1234 O O   . THR A 197 ? 0.55363 0.70384 0.60732 -0.12619 0.04976  -0.01852 196 THR A O   
1235 C CB  . THR A 197 ? 0.54369 0.70477 0.58881 -0.15165 0.06481  -0.00356 196 THR A CB  
1236 O OG1 . THR A 197 ? 0.54823 0.67256 0.58260 -0.14447 0.06447  0.00109  196 THR A OG1 
1237 C CG2 . THR A 197 ? 0.55673 0.73932 0.60183 -0.15265 0.06988  0.00202  196 THR A CG2 
1238 N N   . VAL A 198 ? 0.55680 0.72387 0.61246 -0.15663 0.05517  -0.01989 197 VAL A N   
1239 C CA  . VAL A 198 ? 0.53902 0.69479 0.59321 -0.15988 0.05124  -0.02680 197 VAL A CA  
1240 C C   . VAL A 198 ? 0.56624 0.67660 0.60699 -0.15873 0.05366  -0.02512 197 VAL A C   
1241 O O   . VAL A 198 ? 0.58209 0.66952 0.61368 -0.16475 0.05928  -0.01901 197 VAL A O   
1242 C CB  . VAL A 198 ? 0.61865 0.79328 0.67606 -0.18087 0.05122  -0.03115 197 VAL A CB  
1243 C CG1 . VAL A 198 ? 0.65579 0.81095 0.70326 -0.20075 0.05811  -0.02708 197 VAL A CG1 
1244 C CG2 . VAL A 198 ? 0.59160 0.75817 0.64604 -0.18379 0.04620  -0.03919 197 VAL A CG2 
1245 N N   . TYR A 199 ? 0.54113 0.63880 0.58049 -0.14956 0.04994  -0.02974 198 TYR A N   
1246 C CA  . TYR A 199 ? 0.57841 0.63582 0.60583 -0.14814 0.05296  -0.02934 198 TYR A CA  
1247 C C   . TYR A 199 ? 0.65025 0.69471 0.66892 -0.16485 0.05428  -0.03663 198 TYR A C   
1248 O O   . TYR A 199 ? 0.61696 0.68491 0.64083 -0.17089 0.04949  -0.04351 198 TYR A O   
1249 C CB  . TYR A 199 ? 0.52778 0.57883 0.55781 -0.12948 0.04923  -0.03008 198 TYR A CB  
1250 C CG  . TYR A 199 ? 0.55870 0.61432 0.59353 -0.11425 0.04772  -0.02308 198 TYR A CG  
1251 C CD1 . TYR A 199 ? 0.50581 0.59067 0.54963 -0.10696 0.04328  -0.02366 198 TYR A CD1 
1252 C CD2 . TYR A 199 ? 0.50371 0.53395 0.53295 -0.10685 0.05064  -0.01589 198 TYR A CD2 
1253 C CE1 . TYR A 199 ? 0.44157 0.52784 0.48655 -0.09484 0.04161  -0.01839 198 TYR A CE1 
1254 C CE2 . TYR A 199 ? 0.44259 0.47869 0.47531 -0.09485 0.04808  -0.00962 198 TYR A CE2 
1255 C CZ  . TYR A 199 ? 0.48346 0.54641 0.52301 -0.08987 0.04343  -0.01148 198 TYR A CZ  
1256 O OH  . TYR A 199 ? 0.44709 0.51324 0.48699 -0.07967 0.04062  -0.00627 198 TYR A OH  
1257 N N   . THR A 200 ? 0.68344 0.68936 0.68726 -0.17216 0.06073  -0.03496 199 THR A N   
1258 C CA  . THR A 200 ? 0.70853 0.69284 0.69880 -0.18826 0.06291  -0.04269 199 THR A CA  
1259 C C   . THR A 200 ? 0.73375 0.67723 0.71067 -0.17850 0.06695  -0.04450 199 THR A C   
1260 O O   . THR A 200 ? 0.77983 0.70000 0.74192 -0.19012 0.06946  -0.05206 199 THR A O   
1261 C CB  . THR A 200 ? 0.74058 0.71128 0.72071 -0.21018 0.06859  -0.04058 199 THR A CB  
1262 O OG1 . THR A 200 ? 0.77534 0.71773 0.74830 -0.20331 0.07522  -0.03054 199 THR A OG1 
1263 C CG2 . THR A 200 ? 0.64884 0.66492 0.64299 -0.22238 0.06514  -0.03989 199 THR A CG2 
1264 N N   . ASP A 201 ? 0.77465 0.70963 0.75580 -0.15793 0.06789  -0.03784 200 ASP A N   
1265 C CA  . ASP A 201 ? 0.79383 0.69709 0.76611 -0.14532 0.07201  -0.03833 200 ASP A CA  
1266 C C   . ASP A 201 ? 0.76808 0.69280 0.75251 -0.12920 0.06609  -0.04014 200 ASP A C   
1267 O O   . ASP A 201 ? 0.72360 0.68058 0.72263 -0.12320 0.05979  -0.03767 200 ASP A O   
1268 C CB  . ASP A 201 ? 0.82253 0.69840 0.79007 -0.13444 0.07848  -0.02729 200 ASP A CB  
1269 C CG  . ASP A 201 ? 0.86533 0.76653 0.84837 -0.12093 0.07392  -0.01794 200 ASP A CG  
1270 O OD1 . ASP A 201 ? 0.82942 0.76181 0.82194 -0.12684 0.06897  -0.01801 200 ASP A OD1 
1271 O OD2 . ASP A 201 ? 0.87452 0.76530 0.85980 -0.10441 0.07535  -0.01059 200 ASP A OD2 
1272 N N   . PHE A 202 ? 0.73517 0.63980 0.71183 -0.12228 0.06891  -0.04443 201 PHE A N   
1273 C CA  . PHE A 202 ? 0.70799 0.62943 0.69413 -0.10817 0.06438  -0.04574 201 PHE A CA  
1274 C C   . PHE A 202 ? 0.70587 0.59733 0.68191 -0.09817 0.07128  -0.04677 201 PHE A C   
1275 O O   . PHE A 202 ? 0.75599 0.62094 0.71484 -0.10676 0.07675  -0.05377 201 PHE A O   
1276 C CB  . PHE A 202 ? 0.68371 0.63244 0.67314 -0.11635 0.05709  -0.05442 201 PHE A CB  
1277 C CG  . PHE A 202 ? 0.64242 0.60597 0.63925 -0.10293 0.05270  -0.05541 201 PHE A CG  
1278 C CD1 . PHE A 202 ? 0.64215 0.62908 0.65380 -0.09161 0.04747  -0.04958 201 PHE A CD1 
1279 C CD2 . PHE A 202 ? 0.64296 0.59531 0.62974 -0.10253 0.05411  -0.06230 201 PHE A CD2 
1280 C CE1 . PHE A 202 ? 0.61862 0.61638 0.63544 -0.08080 0.04374  -0.05007 201 PHE A CE1 
1281 C CE2 . PHE A 202 ? 0.61885 0.58429 0.61150 -0.09100 0.05057  -0.06231 201 PHE A CE2 
1282 C CZ  . PHE A 202 ? 0.58856 0.57632 0.59651 -0.08051 0.04534  -0.05594 201 PHE A CZ  
1283 N N   . ASP A 203 ? 0.69654 0.59258 0.68258 -0.08049 0.07133  -0.03991 202 ASP A N   
1284 C CA  . ASP A 203 ? 0.73377 0.60782 0.71370 -0.06834 0.07839  -0.03955 202 ASP A CA  
1285 C C   . ASP A 203 ? 0.68949 0.58552 0.68092 -0.05709 0.07404  -0.03925 202 ASP A C   
1286 O O   . ASP A 203 ? 0.74613 0.63258 0.73845 -0.04407 0.07943  -0.03568 202 ASP A O   
1287 C CB  . ASP A 203 ? 0.73122 0.58456 0.71109 -0.05687 0.08538  -0.02878 202 ASP A CB  
1288 N N   . GLY A 204 ? 0.65773 0.58288 0.65773 -0.06147 0.06499  -0.04228 203 GLY A N   
1289 C CA  . GLY A 204 ? 0.59639 0.53991 0.60494 -0.05263 0.06071  -0.04201 203 GLY A CA  
1290 C C   . GLY A 204 ? 0.61781 0.55454 0.61499 -0.05500 0.06270  -0.05070 203 GLY A C   
1291 O O   . GLY A 204 ? 0.63429 0.54563 0.61605 -0.05911 0.06988  -0.05603 203 GLY A O   
1292 N N   . THR A 205 ? 0.55185 0.50946 0.55445 -0.05247 0.05648  -0.05221 204 THR A N   
1293 C CA  . THR A 205 ? 0.56353 0.51815 0.55547 -0.05332 0.05748  -0.05910 204 THR A CA  
1294 C C   . THR A 205 ? 0.53375 0.50130 0.51925 -0.06637 0.05067  -0.06705 204 THR A C   
1295 O O   . THR A 205 ? 0.48683 0.47919 0.48251 -0.06740 0.04256  -0.06534 204 THR A O   
1296 C CB  . THR A 205 ? 0.51214 0.48072 0.51272 -0.04238 0.05525  -0.05450 204 THR A CB  
1297 O OG1 . THR A 205 ? 0.51327 0.47454 0.52184 -0.03137 0.06115  -0.04638 204 THR A OG1 
1298 C CG2 . THR A 205 ? 0.53840 0.50302 0.52604 -0.04305 0.05704  -0.06088 204 THR A CG2 
1299 N N   . ARG A 206 ? 0.54106 0.49221 0.50895 -0.07593 0.05407  -0.07570 205 ARG A N   
1300 C CA  . ARG A 206 ? 0.56682 0.53105 0.52839 -0.09123 0.04745  -0.08302 205 ARG A CA  
1301 C C   . ARG A 206 ? 0.55307 0.54638 0.51980 -0.08865 0.03837  -0.08346 205 ARG A C   
1302 O O   . ARG A 206 ? 0.50474 0.52317 0.47817 -0.09534 0.03049  -0.08411 205 ARG A O   
1303 C CB  . ARG A 206 ? 0.57232 0.51001 0.51078 -0.10315 0.05286  -0.09282 205 ARG A CB  
1304 C CG  . ARG A 206 ? 0.59847 0.54979 0.53013 -0.12248 0.04581  -0.10024 205 ARG A CG  
1305 C CD  . ARG A 206 ? 0.66676 0.58632 0.57248 -0.13664 0.05154  -0.11056 205 ARG A CD  
1306 N NE  . ARG A 206 ? 0.69435 0.62865 0.59444 -0.15820 0.04424  -0.11718 205 ARG A NE  
1307 C CZ  . ARG A 206 ? 0.72743 0.65965 0.62953 -0.17215 0.04446  -0.11689 205 ARG A CZ  
1308 N NH1 . ARG A 206 ? 0.68004 0.59436 0.58825 -0.16625 0.05143  -0.11019 205 ARG A NH1 
1309 N NH2 . ARG A 206 ? 0.74742 0.69763 0.64533 -0.19303 0.03733  -0.12278 205 ARG A NH2 
1310 N N   . VAL A 207 ? 0.47599 0.46700 0.43959 -0.07847 0.03977  -0.08237 206 VAL A N   
1311 C CA  . VAL A 207 ? 0.47622 0.49114 0.44208 -0.07534 0.03162  -0.08188 206 VAL A CA  
1312 C C   . VAL A 207 ? 0.47483 0.51173 0.45902 -0.06689 0.02561  -0.07412 206 VAL A C   
1313 O O   . VAL A 207 ? 0.47055 0.52750 0.45710 -0.06369 0.01849  -0.07296 206 VAL A O   
1314 C CB  . VAL A 207 ? 0.51856 0.52379 0.47442 -0.06741 0.03544  -0.08207 206 VAL A CB  
1315 C CG1 . VAL A 207 ? 0.51261 0.49985 0.44560 -0.07690 0.03959  -0.09184 206 VAL A CG1 
1316 C CG2 . VAL A 207 ? 0.48423 0.47600 0.44790 -0.05527 0.04327  -0.07517 206 VAL A CG2 
1317 N N   . TYR A 208 ? 0.45809 0.49038 0.45347 -0.06281 0.02840  -0.06871 207 TYR A N   
1318 C CA  . TYR A 208 ? 0.44472 0.49493 0.45447 -0.05675 0.02319  -0.06276 207 TYR A CA  
1319 C C   . TYR A 208 ? 0.44182 0.50374 0.45749 -0.06476 0.02089  -0.06357 207 TYR A C   
1320 O O   . TYR A 208 ? 0.37889 0.45516 0.40485 -0.05984 0.01748  -0.05934 207 TYR A O   
1321 C CB  . TYR A 208 ? 0.44201 0.48226 0.45973 -0.04710 0.02689  -0.05553 207 TYR A CB  
1322 C CG  . TYR A 208 ? 0.42996 0.46825 0.44718 -0.03821 0.02722  -0.05213 207 TYR A CG  
1323 C CD1 . TYR A 208 ? 0.39916 0.42317 0.40781 -0.03682 0.03348  -0.05367 207 TYR A CD1 
1324 C CD2 . TYR A 208 ? 0.38442 0.43353 0.40842 -0.03155 0.02209  -0.04729 207 TYR A CD2 
1325 C CE1 . TYR A 208 ? 0.42688 0.45093 0.43553 -0.02967 0.03450  -0.04974 207 TYR A CE1 
1326 C CE2 . TYR A 208 ? 0.39384 0.43998 0.41659 -0.02544 0.02260  -0.04362 207 TYR A CE2 
1327 C CZ  . TYR A 208 ? 0.37541 0.41067 0.39144 -0.02484 0.02879  -0.04447 207 TYR A CZ  
1328 O OH  . TYR A 208 ? 0.38787 0.42203 0.40320 -0.01971 0.02994  -0.04003 207 TYR A OH  
1329 N N   . SER A 209 ? 0.50714 0.56191 0.51502 -0.07792 0.02331  -0.06911 208 SER A N   
1330 C CA  . SER A 209 ? 0.48318 0.54804 0.49650 -0.08741 0.02243  -0.06909 208 SER A CA  
1331 C C   . SER A 209 ? 0.45814 0.55463 0.47555 -0.09347 0.01481  -0.07187 208 SER A C   
1332 O O   . SER A 209 ? 0.46849 0.57315 0.47949 -0.09514 0.01072  -0.07583 208 SER A O   
1333 C CB  . SER A 209 ? 0.50886 0.54912 0.51099 -0.09994 0.02896  -0.07297 208 SER A CB  
1334 O OG  . SER A 209 ? 0.52491 0.56199 0.51345 -0.11170 0.02785  -0.08127 208 SER A OG  
1335 N N   . PRO A 210 ? 0.47283 0.58943 0.50090 -0.09621 0.01293  -0.06925 209 PRO A N   
1336 C CA  . PRO A 210 ? 0.45239 0.60472 0.48804 -0.09803 0.00599  -0.06996 209 PRO A CA  
1337 C C   . PRO A 210 ? 0.47261 0.63504 0.50282 -0.11703 0.00393  -0.07597 209 PRO A C   
1338 O O   . PRO A 210 ? 0.49417 0.63368 0.51477 -0.13028 0.00889  -0.07947 209 PRO A O   
1339 C CB  . PRO A 210 ? 0.42647 0.59379 0.47468 -0.09345 0.00695  -0.06471 209 PRO A CB  
1340 C CG  . PRO A 210 ? 0.44430 0.58611 0.48868 -0.10025 0.01385  -0.06348 209 PRO A CG  
1341 C CD  . PRO A 210 ? 0.45360 0.56321 0.48767 -0.09581 0.01735  -0.06445 209 PRO A CD  
1342 N N   . PRO A 211 ? 0.47415 0.67063 0.50960 -0.11920 -0.00345 -0.07699 210 PRO A N   
1343 C CA  . PRO A 211 ? 0.47516 0.68470 0.50508 -0.13965 -0.00689 -0.08291 210 PRO A CA  
1344 C C   . PRO A 211 ? 0.51139 0.72544 0.54576 -0.15637 -0.00347 -0.08308 210 PRO A C   
1345 O O   . PRO A 211 ? 0.49989 0.70705 0.52389 -0.17693 -0.00346 -0.08897 210 PRO A O   
1346 C CB  . PRO A 211 ? 0.47945 0.73163 0.51847 -0.13430 -0.01620 -0.08114 210 PRO A CB  
1347 C CG  . PRO A 211 ? 0.44180 0.70554 0.49420 -0.11313 -0.01569 -0.07377 210 PRO A CG  
1348 C CD  . PRO A 211 ? 0.45662 0.68078 0.50219 -0.10307 -0.00914 -0.07247 210 PRO A CD  
1349 N N   . GLU A 212 ? 0.46800 0.69197 0.51558 -0.14924 -0.00031 -0.07693 211 GLU A N   
1350 C CA  . GLU A 212 ? 0.48798 0.71493 0.53870 -0.16545 0.00389  -0.07610 211 GLU A CA  
1351 C C   . GLU A 212 ? 0.53073 0.71093 0.56560 -0.17489 0.01155  -0.07843 211 GLU A C   
1352 O O   . GLU A 212 ? 0.57663 0.75069 0.60665 -0.19430 0.01465  -0.08006 211 GLU A O   
1353 C CB  . GLU A 212 ? 0.44488 0.69186 0.51108 -0.15426 0.00630  -0.06883 211 GLU A CB  
1354 C CG  . GLU A 212 ? 0.45465 0.67534 0.51931 -0.13558 0.01059  -0.06456 211 GLU A CG  
1355 C CD  . GLU A 212 ? 0.44874 0.68182 0.51890 -0.11461 0.00617  -0.06253 211 GLU A CD  
1356 O OE1 . GLU A 212 ? 0.42976 0.67935 0.49999 -0.11282 0.00013  -0.06501 211 GLU A OE1 
1357 O OE2 . GLU A 212 ? 0.43184 0.65702 0.50473 -0.10046 0.00859  -0.05825 211 GLU A OE2 
1358 N N   . TRP A 213 ? 0.53544 0.68255 0.56200 -0.16133 0.01509  -0.07802 212 TRP A N   
1359 C CA  . TRP A 213 ? 0.57314 0.67562 0.58372 -0.16766 0.02275  -0.08007 212 TRP A CA  
1360 C C   . TRP A 213 ? 0.62005 0.70614 0.61261 -0.18267 0.02210  -0.08929 212 TRP A C   
1361 O O   . TRP A 213 ? 0.64943 0.70868 0.62800 -0.19879 0.02730  -0.09288 212 TRP A O   
1362 C CB  . TRP A 213 ? 0.55195 0.62917 0.56134 -0.14777 0.02690  -0.07586 212 TRP A CB  
1363 C CG  . TRP A 213 ? 0.59165 0.62483 0.58384 -0.15042 0.03462  -0.07845 212 TRP A CG  
1364 C CD1 . TRP A 213 ? 0.62496 0.63728 0.60528 -0.14475 0.03654  -0.08285 212 TRP A CD1 
1365 C CD2 . TRP A 213 ? 0.62860 0.63224 0.61222 -0.15845 0.04238  -0.07643 212 TRP A CD2 
1366 N NE1 . TRP A 213 ? 0.66379 0.63563 0.62911 -0.14746 0.04551  -0.08402 212 TRP A NE1 
1367 C CE2 . TRP A 213 ? 0.66127 0.62588 0.62799 -0.15564 0.04901  -0.07987 212 TRP A CE2 
1368 C CE3 . TRP A 213 ? 0.69268 0.69833 0.68033 -0.16696 0.04499  -0.07144 212 TRP A CE3 
1369 C CZ2 . TRP A 213 ? 0.71615 0.64227 0.66970 -0.15994 0.05805  -0.07834 212 TRP A CZ2 
1370 C CZ3 . TRP A 213 ? 0.68265 0.65003 0.65686 -0.17266 0.05344  -0.06954 212 TRP A CZ3 
1371 C CH2 . TRP A 213 ? 0.71559 0.64289 0.67284 -0.16854 0.05983  -0.07289 212 TRP A CH2 
1372 N N   . ILE A 214 ? 0.60667 0.70636 0.59706 -0.17786 0.01596  -0.09319 213 ILE A N   
1373 C CA  . ILE A 214 ? 0.56633 0.65174 0.53718 -0.19208 0.01465  -0.10262 213 ILE A CA  
1374 C C   . ILE A 214 ? 0.62600 0.72757 0.59399 -0.21817 0.01108  -0.10723 213 ILE A C   
1375 O O   . ILE A 214 ? 0.68332 0.75562 0.63098 -0.23624 0.01454  -0.11466 213 ILE A O   
1376 C CB  . ILE A 214 ? 0.55273 0.65619 0.52295 -0.18165 0.00760  -0.10442 213 ILE A CB  
1377 C CG1 . ILE A 214 ? 0.55935 0.64718 0.53255 -0.15794 0.01144  -0.09933 213 ILE A CG1 
1378 C CG2 . ILE A 214 ? 0.63836 0.72742 0.58568 -0.19700 0.00591  -0.11467 213 ILE A CG2 
1379 C CD1 . ILE A 214 ? 0.60695 0.64857 0.56346 -0.15496 0.02125  -0.10209 213 ILE A CD1 
1380 N N   . ARG A 215 ? 0.60819 0.75618 0.59589 -0.22087 0.00463  -0.10282 214 ARG A N   
1381 C CA  . ARG A 215 ? 0.63286 0.80593 0.62110 -0.24647 -0.00012 -0.10641 214 ARG A CA  
1382 C C   . ARG A 215 ? 0.67601 0.83340 0.66339 -0.26196 0.00716  -0.10433 214 ARG A C   
1383 O O   . ARG A 215 ? 0.71439 0.85394 0.68590 -0.28666 0.00861  -0.11058 214 ARG A O   
1384 C CB  . ARG A 215 ? 0.65201 0.88588 0.66310 -0.24186 -0.00958 -0.10164 214 ARG A CB  
1385 C CG  . ARG A 215 ? 0.66208 0.91646 0.67096 -0.23398 -0.01874 -0.10419 214 ARG A CG  
1386 C CD  . ARG A 215 ? 0.62951 0.94557 0.66078 -0.23063 -0.02784 -0.09869 214 ARG A CD  
1387 N N   . TYR A 216 ? 0.62953 0.79175 0.63180 -0.24870 0.01183  -0.09558 215 TYR A N   
1388 C CA  . TYR A 216 ? 0.67947 0.83731 0.68405 -0.26297 0.01777  -0.09162 215 TYR A CA  
1389 C C   . TYR A 216 ? 0.66789 0.77817 0.66283 -0.25407 0.02802  -0.08746 215 TYR A C   
1390 O O   . TYR A 216 ? 0.69667 0.79895 0.69128 -0.26491 0.03363  -0.08310 215 TYR A O   
1391 C CB  . TYR A 216 ? 0.64035 0.85026 0.67041 -0.25801 0.01490  -0.08398 215 TYR A CB  
1392 C CG  . TYR A 216 ? 0.69766 0.96068 0.74170 -0.25908 0.00465  -0.08542 215 TYR A CG  
1393 C CD1 . TYR A 216 ? 0.71953 1.00356 0.76045 -0.28495 -0.00099 -0.09072 215 TYR A CD1 
1394 C CD2 . TYR A 216 ? 0.66755 0.95954 0.72710 -0.23439 0.00043  -0.08100 215 TYR A CD2 
1395 C CE1 . TYR A 216 ? 0.69503 1.03157 0.74985 -0.28502 -0.01113 -0.09074 215 TYR A CE1 
1396 C CE2 . TYR A 216 ? 0.67833 1.01868 0.75042 -0.23299 -0.00870 -0.08094 215 TYR A CE2 
1397 C CZ  . TYR A 216 ? 0.71417 1.07869 0.78484 -0.25774 -0.01472 -0.08538 215 TYR A CZ  
1398 O OH  . TYR A 216 ? 0.83373 1.25014 0.91797 -0.25542 -0.02455 -0.08409 215 TYR A OH  
1399 N N   . HIS A 217 ? 0.66960 0.75023 0.65713 -0.23475 0.03065  -0.08776 216 HIS A N   
1400 C CA  . HIS A 217 ? 0.70306 0.74429 0.68434 -0.22304 0.03953  -0.08220 216 HIS A CA  
1401 C C   . HIS A 217 ? 0.66088 0.72192 0.65893 -0.21430 0.04102  -0.07223 216 HIS A C   
1402 O O   . HIS A 217 ? 0.66269 0.69903 0.65542 -0.21564 0.04802  -0.06664 216 HIS A O   
1403 C CB  . HIS A 217 ? 0.71402 0.70825 0.67242 -0.24003 0.04749  -0.08562 216 HIS A CB  
1404 C CG  . HIS A 217 ? 0.83016 0.78460 0.76804 -0.23589 0.05097  -0.09284 216 HIS A CG  
1405 N ND1 . HIS A 217 ? 0.89706 0.79860 0.81342 -0.23910 0.06084  -0.09390 216 HIS A ND1 
1406 C CD2 . HIS A 217 ? 0.84311 0.80227 0.77756 -0.22783 0.04675  -0.09900 216 HIS A CD2 
1407 C CE1 . HIS A 217 ? 0.95517 0.83131 0.85604 -0.23273 0.06305  -0.10098 216 HIS A CE1 
1408 N NE2 . HIS A 217 ? 0.90640 0.81723 0.81777 -0.22655 0.05449  -0.10416 216 HIS A NE2 
1409 N N   . ARG A 218 ? 0.65209 0.75668 0.66875 -0.20456 0.03471  -0.06980 217 ARG A N   
1410 C CA  . ARG A 218 ? 0.61204 0.73767 0.64312 -0.19496 0.03600  -0.06156 217 ARG A CA  
1411 C C   . ARG A 218 ? 0.53525 0.68211 0.57825 -0.17224 0.03096  -0.05979 217 ARG A C   
1412 O O   . ARG A 218 ? 0.57732 0.74205 0.62334 -0.16870 0.02478  -0.06420 217 ARG A O   
1413 C CB  . ARG A 218 ? 0.59153 0.75422 0.63294 -0.21144 0.03508  -0.06015 217 ARG A CB  
1414 C CG  . ARG A 218 ? 0.69747 0.83950 0.72768 -0.23509 0.04111  -0.05971 217 ARG A CG  
1415 C CD  . ARG A 218 ? 0.71207 0.89702 0.75342 -0.25487 0.03875  -0.05980 217 ARG A CD  
1416 N NE  . ARG A 218 ? 0.77582 1.00459 0.83734 -0.24207 0.03771  -0.05371 217 ARG A NE  
1417 C CZ  . ARG A 218 ? 0.82109 1.05777 0.88746 -0.24392 0.04373  -0.04643 217 ARG A CZ  
1418 N NH1 . ARG A 218 ? 0.83201 1.03640 0.88537 -0.25819 0.05085  -0.04318 217 ARG A NH1 
1419 N NH2 . ARG A 218 ? 0.76023 1.03661 0.84323 -0.23058 0.04318  -0.04211 217 ARG A NH2 
1420 N N   . TYR A 219 ? 0.52878 0.67251 0.57679 -0.15761 0.03347  -0.05317 218 TYR A N   
1421 C CA  . TYR A 219 ? 0.49105 0.65212 0.54834 -0.13752 0.02927  -0.05139 218 TYR A CA  
1422 C C   . TYR A 219 ? 0.51595 0.67735 0.57700 -0.12822 0.03256  -0.04443 218 TYR A C   
1423 O O   . TYR A 219 ? 0.52810 0.66828 0.58286 -0.13342 0.03785  -0.04019 218 TYR A O   
1424 C CB  . TYR A 219 ? 0.46620 0.60484 0.51729 -0.12540 0.02733  -0.05361 218 TYR A CB  
1425 C CG  . TYR A 219 ? 0.53177 0.63259 0.57397 -0.12125 0.03270  -0.05022 218 TYR A CG  
1426 C CD1 . TYR A 219 ? 0.51302 0.58399 0.54265 -0.13164 0.03731  -0.05286 218 TYR A CD1 
1427 C CD2 . TYR A 219 ? 0.47086 0.56595 0.51646 -0.10666 0.03318  -0.04420 218 TYR A CD2 
1428 C CE1 . TYR A 219 ? 0.54790 0.58582 0.57021 -0.12528 0.04284  -0.04866 218 TYR A CE1 
1429 C CE2 . TYR A 219 ? 0.49352 0.55900 0.53296 -0.10205 0.03746  -0.03981 218 TYR A CE2 
1430 C CZ  . TYR A 219 ? 0.55276 0.59051 0.58141 -0.11022 0.04257  -0.04158 218 TYR A CZ  
1431 O OH  . TYR A 219 ? 0.55730 0.56696 0.58056 -0.10319 0.04746  -0.03615 218 TYR A OH  
1432 N N   . HIS A 220 ? 0.49408 0.67831 0.56353 -0.11414 0.02946  -0.04321 219 HIS A N   
1433 C CA  . HIS A 220 ? 0.46226 0.64394 0.53214 -0.10291 0.03155  -0.03793 219 HIS A CA  
1434 C C   . HIS A 220 ? 0.43103 0.59389 0.49735 -0.08761 0.02858  -0.03753 219 HIS A C   
1435 O O   . HIS A 220 ? 0.40541 0.56829 0.47217 -0.08231 0.02457  -0.04118 219 HIS A O   
1436 C CB  . HIS A 220 ? 0.45075 0.66749 0.52956 -0.09764 0.03146  -0.03714 219 HIS A CB  
1437 C CG  . HIS A 220 ? 0.47190 0.71010 0.55561 -0.11297 0.03551  -0.03571 219 HIS A CG  
1438 N ND1 . HIS A 220 ? 0.45777 0.71543 0.54698 -0.12697 0.03377  -0.03908 219 HIS A ND1 
1439 C CD2 . HIS A 220 ? 0.49050 0.73419 0.57375 -0.11801 0.04122  -0.03089 219 HIS A CD2 
1440 C CE1 . HIS A 220 ? 0.47985 0.75519 0.57309 -0.14066 0.03830  -0.03631 219 HIS A CE1 
1441 N NE2 . HIS A 220 ? 0.49286 0.75961 0.58238 -0.13509 0.04333  -0.03114 219 HIS A NE2 
1442 N N   . GLY A 221 ? 0.38399 0.53199 0.44635 -0.08152 0.03039  -0.03253 220 GLY A N   
1443 C CA  . GLY A 221 ? 0.41937 0.54699 0.47823 -0.07116 0.02802  -0.03103 220 GLY A CA  
1444 C C   . GLY A 221 ? 0.43233 0.56931 0.49342 -0.05901 0.02309  -0.03381 220 GLY A C   
1445 O O   . GLY A 221 ? 0.38844 0.51520 0.44852 -0.05478 0.02058  -0.03545 220 GLY A O   
1446 N N   . ARG A 222 ? 0.40078 0.55566 0.46351 -0.05282 0.02244  -0.03412 221 ARG A N   
1447 C CA  . ARG A 222 ? 0.38937 0.54706 0.45091 -0.04005 0.01853  -0.03609 221 ARG A CA  
1448 C C   . ARG A 222 ? 0.39016 0.55957 0.45566 -0.03824 0.01558  -0.03999 221 ARG A C   
1449 O O   . ARG A 222 ? 0.37876 0.53835 0.44144 -0.03123 0.01226  -0.04087 221 ARG A O   
1450 C CB  . ARG A 222 ? 0.41168 0.58254 0.47128 -0.03279 0.01996  -0.03585 221 ARG A CB  
1451 C CG  . ARG A 222 ? 0.46426 0.62345 0.51724 -0.03435 0.02206  -0.03195 221 ARG A CG  
1452 C CD  . ARG A 222 ? 0.54161 0.71510 0.59084 -0.02882 0.02511  -0.03241 221 ARG A CD  
1453 N NE  . ARG A 222 ? 0.57434 0.73692 0.61500 -0.03114 0.02668  -0.02855 221 ARG A NE  
1454 C CZ  . ARG A 222 ? 0.62350 0.79009 0.66443 -0.04029 0.03094  -0.02449 221 ARG A CZ  
1455 N NH1 . ARG A 222 ? 0.58453 0.76453 0.63383 -0.04969 0.03431  -0.02417 221 ARG A NH1 
1456 N NH2 . ARG A 222 ? 0.62369 0.78032 0.65506 -0.04097 0.03160  -0.02035 221 ARG A NH2 
1457 N N   . SER A 223 ? 0.38129 0.57307 0.45302 -0.04529 0.01647  -0.04179 222 SER A N   
1458 C CA  . SER A 223 ? 0.38470 0.59127 0.45988 -0.04395 0.01260  -0.04488 222 SER A CA  
1459 C C   . SER A 223 ? 0.37768 0.56542 0.44835 -0.05028 0.01102  -0.04687 222 SER A C   
1460 O O   . SER A 223 ? 0.40271 0.59217 0.47178 -0.04510 0.00718  -0.04862 222 SER A O   
1461 C CB  . SER A 223 ? 0.38645 0.62561 0.47046 -0.05190 0.01325  -0.04580 222 SER A CB  
1462 O OG  . SER A 223 ? 0.44964 0.68481 0.53376 -0.06865 0.01684  -0.04558 222 SER A OG  
1463 N N   . ALA A 224 ? 0.37768 0.54620 0.44484 -0.06039 0.01454  -0.04628 223 ALA A N   
1464 C CA  . ALA A 224 ? 0.41015 0.55742 0.47119 -0.06422 0.01474  -0.04825 223 ALA A CA  
1465 C C   . ALA A 224 ? 0.41548 0.54579 0.47347 -0.05250 0.01347  -0.04609 223 ALA A C   
1466 O O   . ALA A 224 ? 0.39219 0.51507 0.44641 -0.05057 0.01205  -0.04800 223 ALA A O   
1467 C CB  . ALA A 224 ? 0.43938 0.56748 0.49613 -0.07569 0.02003  -0.04748 223 ALA A CB  
1468 N N   . ALA A 225 ? 0.40268 0.52737 0.46143 -0.04574 0.01394  -0.04200 224 ALA A N   
1469 C CA  . ALA A 225 ? 0.39154 0.50257 0.44784 -0.03677 0.01212  -0.03962 224 ALA A CA  
1470 C C   . ALA A 225 ? 0.38769 0.50674 0.44257 -0.02848 0.00797  -0.04149 224 ALA A C   
1471 O O   . ALA A 225 ? 0.36254 0.47098 0.41430 -0.02489 0.00672  -0.04100 224 ALA A O   
1472 C CB  . ALA A 225 ? 0.36577 0.47159 0.42165 -0.03318 0.01230  -0.03536 224 ALA A CB  
1473 N N   . VAL A 226 ? 0.36763 0.50576 0.42454 -0.02471 0.00637  -0.04294 225 VAL A N   
1474 C CA  . VAL A 226 ? 0.36204 0.50715 0.41665 -0.01468 0.00275  -0.04365 225 VAL A CA  
1475 C C   . VAL A 226 ? 0.37814 0.52685 0.43161 -0.01753 0.00063  -0.04567 225 VAL A C   
1476 O O   . VAL A 226 ? 0.35698 0.49904 0.40537 -0.01065 -0.00184 -0.04482 225 VAL A O   
1477 C CB  . VAL A 226 ? 0.38294 0.55021 0.44090 -0.00839 0.00264  -0.04412 225 VAL A CB  
1478 C CG1 . VAL A 226 ? 0.35330 0.52987 0.40916 0.00311  -0.00082 -0.04410 225 VAL A CG1 
1479 C CG2 . VAL A 226 ? 0.40842 0.56758 0.46287 -0.00365 0.00484  -0.04268 225 VAL A CG2 
1480 N N   . TRP A 227 ? 0.34156 0.49918 0.39773 -0.02869 0.00162  -0.04839 226 TRP A N   
1481 C CA  . TRP A 227 ? 0.37525 0.53422 0.42730 -0.03327 -0.00045 -0.05124 226 TRP A CA  
1482 C C   . TRP A 227 ? 0.36747 0.50121 0.41251 -0.03207 0.00142  -0.05055 226 TRP A C   
1483 O O   . TRP A 227 ? 0.38971 0.52144 0.42916 -0.02773 -0.00091 -0.05061 226 TRP A O   
1484 C CB  . TRP A 227 ? 0.36410 0.53184 0.41737 -0.04828 0.00073  -0.05511 226 TRP A CB  
1485 C CG  . TRP A 227 ? 0.38800 0.55300 0.43335 -0.05488 -0.00115 -0.05919 226 TRP A CG  
1486 C CD1 . TRP A 227 ? 0.40339 0.54334 0.43953 -0.05898 0.00238  -0.06131 226 TRP A CD1 
1487 C CD2 . TRP A 227 ? 0.38246 0.57146 0.42726 -0.05751 -0.00691 -0.06150 226 TRP A CD2 
1488 N NE1 . TRP A 227 ? 0.42864 0.57305 0.45642 -0.06463 -0.00047 -0.06568 226 TRP A NE1 
1489 C CE2 . TRP A 227 ? 0.39477 0.56987 0.42777 -0.06449 -0.00690 -0.06568 226 TRP A CE2 
1490 C CE3 . TRP A 227 ? 0.38221 0.60473 0.43531 -0.05397 -0.01195 -0.06002 226 TRP A CE3 
1491 C CZ2 . TRP A 227 ? 0.43887 0.63199 0.46678 -0.06957 -0.01277 -0.06870 226 TRP A CZ2 
1492 C CZ3 . TRP A 227 ? 0.39599 0.63915 0.44651 -0.05814 -0.01802 -0.06203 226 TRP A CZ3 
1493 C CH2 . TRP A 227 ? 0.39964 0.62774 0.43699 -0.06658 -0.01888 -0.06646 226 TRP A CH2 
1494 N N   . SER A 228 ? 0.36840 0.48422 0.41383 -0.03536 0.00594  -0.04908 227 SER A N   
1495 C CA  . SER A 228 ? 0.36893 0.46463 0.40999 -0.03338 0.00864  -0.04751 227 SER A CA  
1496 C C   . SER A 228 ? 0.36433 0.45636 0.40439 -0.02345 0.00606  -0.04373 227 SER A C   
1497 O O   . SER A 228 ? 0.34652 0.42907 0.38210 -0.02132 0.00695  -0.04269 227 SER A O   
1498 C CB  . SER A 228 ? 0.37274 0.45341 0.41617 -0.03665 0.01377  -0.04504 227 SER A CB  
1499 O OG  . SER A 228 ? 0.41776 0.49968 0.46623 -0.03228 0.01264  -0.04066 227 SER A OG  
1500 N N   . LEU A 229 ? 0.33006 0.42806 0.37263 -0.01783 0.00344  -0.04178 228 LEU A N   
1501 C CA  . LEU A 229 ? 0.35102 0.44219 0.38959 -0.00952 0.00090  -0.03881 228 LEU A CA  
1502 C C   . LEU A 229 ? 0.34790 0.44503 0.38070 -0.00419 -0.00218 -0.03950 228 LEU A C   
1503 O O   . LEU A 229 ? 0.37686 0.46291 0.40372 0.00009  -0.00298 -0.03674 228 LEU A O   
1504 C CB  . LEU A 229 ? 0.34518 0.43814 0.38427 -0.00491 -0.00046 -0.03779 228 LEU A CB  
1505 C CG  . LEU A 229 ? 0.37937 0.46428 0.42157 -0.00908 0.00140  -0.03553 228 LEU A CG  
1506 C CD1 . LEU A 229 ? 0.41539 0.50459 0.45586 -0.00563 0.00054  -0.03595 228 LEU A CD1 
1507 C CD2 . LEU A 229 ? 0.36015 0.43012 0.40069 -0.00926 0.00108  -0.03165 228 LEU A CD2 
1508 N N   . GLY A 230 ? 0.33437 0.45016 0.36876 -0.00479 -0.00417 -0.04235 229 GLY A N   
1509 C CA  . GLY A 230 ? 0.37718 0.50141 0.40605 0.00013  -0.00780 -0.04218 229 GLY A CA  
1510 C C   . GLY A 230 ? 0.35668 0.47156 0.37898 -0.00499 -0.00661 -0.04304 229 GLY A C   
1511 O O   . GLY A 230 ? 0.34198 0.45146 0.35646 0.00049  -0.00825 -0.04044 229 GLY A O   
1512 N N   . ILE A 231 ? 0.34132 0.45217 0.36496 -0.01512 -0.00299 -0.04651 230 ILE A N   
1513 C CA  . ILE A 231 ? 0.38656 0.48510 0.40235 -0.01920 0.00010  -0.04792 230 ILE A CA  
1514 C C   . ILE A 231 ? 0.41732 0.49899 0.43147 -0.01392 0.00297  -0.04295 230 ILE A C   
1515 O O   . ILE A 231 ? 0.38555 0.46142 0.39159 -0.01190 0.00363  -0.04152 230 ILE A O   
1516 C CB  . ILE A 231 ? 0.37786 0.46970 0.39397 -0.02960 0.00498  -0.05246 230 ILE A CB  
1517 C CG1 . ILE A 231 ? 0.41764 0.52673 0.43472 -0.03804 0.00188  -0.05736 230 ILE A CG1 
1518 C CG2 . ILE A 231 ? 0.37555 0.45204 0.38161 -0.03199 0.00981  -0.05436 230 ILE A CG2 
1519 C CD1 . ILE A 231 ? 0.37248 0.49557 0.38146 -0.04009 -0.00325 -0.06025 230 ILE A CD1 
1520 N N   . LEU A 232 ? 0.36123 0.43631 0.38270 -0.01258 0.00452  -0.03989 231 LEU A N   
1521 C CA  . LEU A 232 ? 0.35606 0.41841 0.37776 -0.00983 0.00659  -0.03472 231 LEU A CA  
1522 C C   . LEU A 232 ? 0.36482 0.42447 0.37947 -0.00350 0.00291  -0.03132 231 LEU A C   
1523 O O   . LEU A 232 ? 0.38136 0.43206 0.39148 -0.00299 0.00484  -0.02772 231 LEU A O   
1524 C CB  . LEU A 232 ? 0.33007 0.38920 0.36025 -0.01070 0.00719  -0.03218 231 LEU A CB  
1525 C CG  . LEU A 232 ? 0.37677 0.42668 0.40877 -0.00983 0.00786  -0.02640 231 LEU A CG  
1526 C CD1 . LEU A 232 ? 0.31582 0.36128 0.34928 -0.01162 0.01359  -0.02422 231 LEU A CD1 
1527 C CD2 . LEU A 232 ? 0.35198 0.40166 0.39081 -0.01138 0.00664  -0.02422 231 LEU A CD2 
1528 N N   . LEU A 233 ? 0.37987 0.44655 0.39295 0.00187  -0.00169 -0.03186 232 LEU A N   
1529 C CA  . LEU A 233 ? 0.37368 0.43342 0.37797 0.00946  -0.00462 -0.02809 232 LEU A CA  
1530 C C   . LEU A 233 ? 0.39633 0.45850 0.39152 0.01154  -0.00555 -0.02712 232 LEU A C   
1531 O O   . LEU A 233 ? 0.41545 0.46523 0.40218 0.01397  -0.00510 -0.02251 232 LEU A O   
1532 C CB  . LEU A 233 ? 0.36268 0.42887 0.36682 0.01711  -0.00806 -0.02884 232 LEU A CB  
1533 C CG  . LEU A 233 ? 0.40518 0.46087 0.39794 0.02736  -0.01056 -0.02493 232 LEU A CG  
1534 C CD1 . LEU A 233 ? 0.42293 0.45503 0.40882 0.02462  -0.00906 -0.02084 232 LEU A CD1 
1535 C CD2 . LEU A 233 ? 0.37196 0.43273 0.36477 0.03633  -0.01211 -0.02618 232 LEU A CD2 
1536 N N   . TYR A 234 ? 0.37608 0.45411 0.37166 0.00946  -0.00704 -0.03118 233 TYR A N   
1537 C CA  . TYR A 234 ? 0.37996 0.46107 0.36528 0.00963  -0.00815 -0.03082 233 TYR A CA  
1538 C C   . TYR A 234 ? 0.41509 0.48156 0.39574 0.00467  -0.00236 -0.02960 233 TYR A C   
1539 O O   . TYR A 234 ? 0.42506 0.48489 0.39512 0.00737  -0.00203 -0.02564 233 TYR A O   
1540 C CB  . TYR A 234 ? 0.37719 0.47782 0.36366 0.00430  -0.01074 -0.03659 233 TYR A CB  
1541 C CG  . TYR A 234 ? 0.40715 0.51373 0.38103 0.00372  -0.01334 -0.03682 233 TYR A CG  
1542 C CD1 . TYR A 234 ? 0.43080 0.52586 0.39572 -0.00259 -0.00854 -0.03892 233 TYR A CD1 
1543 C CD2 . TYR A 234 ? 0.37381 0.49863 0.34409 0.01023  -0.02039 -0.03462 233 TYR A CD2 
1544 C CE1 . TYR A 234 ? 0.43631 0.53597 0.38702 -0.00360 -0.01082 -0.03947 233 TYR A CE1 
1545 C CE2 . TYR A 234 ? 0.43160 0.56327 0.38902 0.00939  -0.02371 -0.03425 233 TYR A CE2 
1546 C CZ  . TYR A 234 ? 0.46128 0.57938 0.40798 0.00181  -0.01895 -0.03705 233 TYR A CZ  
1547 O OH  . TYR A 234 ? 0.47526 0.59917 0.40657 0.00034  -0.02204 -0.03713 233 TYR A OH  
1548 N N   . ASP A 235 ? 0.40885 0.47076 0.39717 -0.00177 0.00281  -0.03221 234 ASP A N   
1549 C CA  . ASP A 235 ? 0.37943 0.43022 0.36567 -0.00492 0.00967  -0.03068 234 ASP A CA  
1550 C C   . ASP A 235 ? 0.43952 0.48014 0.42412 -0.00187 0.01065  -0.02322 234 ASP A C   
1551 O O   . ASP A 235 ? 0.41164 0.44681 0.38862 -0.00222 0.01446  -0.02024 234 ASP A O   
1552 C CB  . ASP A 235 ? 0.39519 0.44334 0.39187 -0.00954 0.01469  -0.03316 234 ASP A CB  
1553 C CG  . ASP A 235 ? 0.43721 0.47638 0.43483 -0.01045 0.02271  -0.03047 234 ASP A CG  
1554 O OD1 . ASP A 235 ? 0.45622 0.49208 0.44349 -0.01078 0.02674  -0.03175 234 ASP A OD1 
1555 O OD2 . ASP A 235 ? 0.39173 0.42874 0.40046 -0.01053 0.02518  -0.02682 234 ASP A OD2 
1556 N N   . MET A 236 ? 0.37882 0.41605 0.36870 0.00028  0.00740  -0.02025 235 MET A N   
1557 C CA  . MET A 236 ? 0.41660 0.44191 0.40373 0.00046  0.00795  -0.01355 235 MET A CA  
1558 C C   . MET A 236 ? 0.43385 0.45261 0.40623 0.00539  0.00550  -0.00973 235 MET A C   
1559 O O   . MET A 236 ? 0.44118 0.45095 0.40747 0.00335  0.00859  -0.00427 235 MET A O   
1560 C CB  . MET A 236 ? 0.39169 0.41234 0.38471 0.00033  0.00475  -0.01263 235 MET A CB  
1561 C CG  . MET A 236 ? 0.41657 0.44126 0.42318 -0.00515 0.00737  -0.01310 235 MET A CG  
1562 S SD  . MET A 236 ? 0.54257 0.55982 0.55159 -0.00698 0.00304  -0.01123 235 MET A SD  
1563 C CE  . MET A 236 ? 0.38773 0.40797 0.39131 0.00073  -0.00142 -0.01664 235 MET A CE  
1564 N N   . VAL A 237 ? 0.39243 0.41650 0.35907 0.01228  0.00017  -0.01150 236 VAL A N   
1565 C CA  . VAL A 237 ? 0.45590 0.47242 0.40787 0.01921  -0.00261 -0.00632 236 VAL A CA  
1566 C C   . VAL A 237 ? 0.46354 0.48782 0.40580 0.01968  -0.00231 -0.00618 236 VAL A C   
1567 O O   . VAL A 237 ? 0.49905 0.51583 0.42751 0.02469  -0.00371 -0.00032 236 VAL A O   
1568 C CB  . VAL A 237 ? 0.43595 0.45459 0.38545 0.02934  -0.00827 -0.00647 236 VAL A CB  
1569 C CG1 . VAL A 237 ? 0.46214 0.46804 0.41577 0.02912  -0.00815 -0.00657 236 VAL A CG1 
1570 C CG2 . VAL A 237 ? 0.45991 0.50256 0.41685 0.03115  -0.01144 -0.01232 236 VAL A CG2 
1571 N N   . CYS A 238 ? 0.45385 0.49072 0.40053 0.01431  -0.00042 -0.01237 237 CYS A N   
1572 C CA  . CYS A 238 ? 0.49319 0.53592 0.42788 0.01307  0.00006  -0.01351 237 CYS A CA  
1573 C C   . CYS A 238 ? 0.47260 0.50895 0.40553 0.00617  0.00855  -0.01471 237 CYS A C   
1574 O O   . CYS A 238 ? 0.52365 0.56046 0.44295 0.00526  0.01038  -0.01480 237 CYS A O   
1575 C CB  . CYS A 238 ? 0.45419 0.51609 0.39038 0.01184  -0.00492 -0.02053 237 CYS A CB  
1576 S SG  . CYS A 238 ? 0.51609 0.59296 0.45226 0.02256  -0.01461 -0.01758 237 CYS A SG  
1577 N N   . GLY A 239 ? 0.43917 0.47060 0.38485 0.00215  0.01400  -0.01522 238 GLY A N   
1578 C CA  . GLY A 239 ? 0.46724 0.49443 0.41328 -0.00203 0.02314  -0.01535 238 GLY A CA  
1579 C C   . GLY A 239 ? 0.46584 0.49654 0.41417 -0.00566 0.02722  -0.02374 238 GLY A C   
1580 O O   . GLY A 239 ? 0.49580 0.52185 0.44511 -0.00717 0.03613  -0.02406 238 GLY A O   
1581 N N   . ASP A 240 ? 0.43109 0.46940 0.37961 -0.00710 0.02160  -0.03024 239 ASP A N   
1582 C CA  . ASP A 240 ? 0.46768 0.50560 0.41748 -0.01229 0.02521  -0.03838 239 ASP A CA  
1583 C C   . ASP A 240 ? 0.48715 0.53624 0.44241 -0.01464 0.01742  -0.04284 239 ASP A C   
1584 O O   . ASP A 240 ? 0.46391 0.52305 0.41974 -0.01089 0.00969  -0.04016 239 ASP A O   
1585 C CB  . ASP A 240 ? 0.48604 0.51932 0.41785 -0.01548 0.02983  -0.04370 239 ASP A CB  
1586 C CG  . ASP A 240 ? 0.55732 0.58070 0.48853 -0.01981 0.03779  -0.05088 239 ASP A CG  
1587 O OD1 . ASP A 240 ? 0.54908 0.57003 0.49510 -0.01950 0.03995  -0.05014 239 ASP A OD1 
1588 O OD2 . ASP A 240 ? 0.63762 0.65386 0.55175 -0.02325 0.04210  -0.05717 239 ASP A OD2 
1589 N N   . ILE A 241 ? 0.47530 0.52226 0.43433 -0.02041 0.02026  -0.04910 240 ILE A N   
1590 C CA  . ILE A 241 ? 0.45775 0.51615 0.42350 -0.02452 0.01431  -0.05301 240 ILE A CA  
1591 C C   . ILE A 241 ? 0.45494 0.52715 0.40952 -0.02852 0.00747  -0.05732 240 ILE A C   
1592 O O   . ILE A 241 ? 0.47739 0.54537 0.41647 -0.03063 0.00893  -0.05979 240 ILE A O   
1593 C CB  . ILE A 241 ? 0.48356 0.53282 0.45405 -0.03075 0.01996  -0.05777 240 ILE A CB  
1594 C CG1 . ILE A 241 ? 0.50201 0.53793 0.45685 -0.03665 0.02632  -0.06470 240 ILE A CG1 
1595 C CG2 . ILE A 241 ? 0.41282 0.45331 0.39610 -0.02580 0.02515  -0.05198 240 ILE A CG2 
1596 C CD1 . ILE A 241 ? 0.50904 0.53105 0.46520 -0.04227 0.03258  -0.06930 240 ILE A CD1 
1597 N N   . PRO A 242 ? 0.45304 0.54402 0.41472 -0.02958 -0.00010 -0.05796 241 PRO A N   
1598 C CA  . PRO A 242 ? 0.46325 0.57316 0.41630 -0.03293 -0.00783 -0.06056 241 PRO A CA  
1599 C C   . PRO A 242 ? 0.51367 0.62364 0.45748 -0.04721 -0.00726 -0.06993 241 PRO A C   
1600 O O   . PRO A 242 ? 0.51071 0.62791 0.44008 -0.05211 -0.01134 -0.07324 241 PRO A O   
1601 C CB  . PRO A 242 ? 0.41659 0.54859 0.38349 -0.02771 -0.01481 -0.05698 241 PRO A CB  
1602 C CG  . PRO A 242 ? 0.44326 0.56700 0.42357 -0.02888 -0.01003 -0.05721 241 PRO A CG  
1603 C CD  . PRO A 242 ? 0.43462 0.53299 0.41245 -0.02660 -0.00205 -0.05532 241 PRO A CD  
1604 N N   . PHE A 243 ? 0.49976 0.60017 0.44971 -0.05462 -0.00236 -0.07418 242 PHE A N   
1605 C CA  . PHE A 243 ? 0.49952 0.59802 0.44060 -0.06998 -0.00209 -0.08320 242 PHE A CA  
1606 C C   . PHE A 243 ? 0.55248 0.61882 0.48291 -0.07362 0.00893  -0.08803 242 PHE A C   
1607 O O   . PHE A 243 ? 0.50355 0.55519 0.44311 -0.06663 0.01593  -0.08402 242 PHE A O   
1608 C CB  . PHE A 243 ? 0.47526 0.58942 0.43077 -0.07693 -0.00537 -0.08392 242 PHE A CB  
1609 C CG  . PHE A 243 ? 0.48480 0.63142 0.45354 -0.07036 -0.01435 -0.07831 242 PHE A CG  
1610 C CD1 . PHE A 243 ? 0.51296 0.68037 0.47569 -0.06759 -0.02242 -0.07682 242 PHE A CD1 
1611 C CD2 . PHE A 243 ? 0.45595 0.61210 0.44209 -0.06577 -0.01426 -0.07411 242 PHE A CD2 
1612 C CE1 . PHE A 243 ? 0.48118 0.67832 0.45612 -0.05896 -0.02985 -0.07083 242 PHE A CE1 
1613 C CE2 . PHE A 243 ? 0.43078 0.61558 0.42804 -0.05775 -0.02103 -0.06912 242 PHE A CE2 
1614 C CZ  . PHE A 243 ? 0.46836 0.67368 0.46059 -0.05358 -0.02863 -0.06725 242 PHE A CZ  
1615 N N   . GLU A 244 ? 0.54447 0.60019 0.45460 -0.08424 0.01047  -0.09660 243 GLU A N   
1616 C CA  . GLU A 244 ? 0.60219 0.62516 0.49882 -0.08816 0.02171  -0.10271 243 GLU A CA  
1617 C C   . GLU A 244 ? 0.67119 0.68423 0.55737 -0.10562 0.02208  -0.11218 243 GLU A C   
1618 O O   . GLU A 244 ? 0.70349 0.68664 0.58200 -0.10768 0.03214  -0.11595 243 GLU A O   
1619 C CB  . GLU A 244 ? 0.66747 0.67629 0.54300 -0.08494 0.02667  -0.10576 243 GLU A CB  
1620 C CG  . GLU A 244 ? 0.70231 0.71169 0.58535 -0.06885 0.03043  -0.09648 243 GLU A CG  
1621 C CD  . GLU A 244 ? 0.68466 0.67405 0.57696 -0.06020 0.04206  -0.09269 243 GLU A CD  
1622 O OE1 . GLU A 244 ? 0.67842 0.64959 0.56849 -0.06492 0.04829  -0.09739 243 GLU A OE1 
1623 O OE2 . GLU A 244 ? 0.66620 0.65852 0.56780 -0.04888 0.04485  -0.08439 243 GLU A OE2 
1624 N N   . HIS A 245 ? 0.64771 0.68486 0.53327 -0.11823 0.01168  -0.11554 244 HIS A N   
1625 C CA  . HIS A 245 ? 0.68509 0.71453 0.55841 -0.13851 0.01092  -0.12500 244 HIS A CA  
1626 C C   . HIS A 245 ? 0.66873 0.72593 0.56218 -0.14603 0.00370  -0.12171 244 HIS A C   
1627 O O   . HIS A 245 ? 0.62173 0.71020 0.53469 -0.13649 -0.00323 -0.11372 244 HIS A O   
1628 C CB  . HIS A 245 ? 0.77921 0.81393 0.62893 -0.15137 0.00477  -0.13360 244 HIS A CB  
1629 C CG  . HIS A 245 ? 0.78444 0.79777 0.61384 -0.14287 0.01114  -0.13606 244 HIS A CG  
1630 N ND1 . HIS A 245 ? 0.82112 0.79379 0.62753 -0.14620 0.02303  -0.14441 244 HIS A ND1 
1631 C CD2 . HIS A 245 ? 0.82258 0.84881 0.65040 -0.13060 0.00820  -0.13077 244 HIS A CD2 
1632 C CE1 . HIS A 245 ? 0.88706 0.85103 0.67943 -0.13638 0.02736  -0.14441 244 HIS A CE1 
1633 N NE2 . HIS A 245 ? 0.91015 0.90609 0.71504 -0.12759 0.01831  -0.13598 244 HIS A NE2 
1634 N N   . ASP A 246 ? 0.67007 0.71397 0.55701 -0.16341 0.00618  -0.12798 245 ASP A N   
1635 C CA  . ASP A 246 ? 0.70064 0.76948 0.60588 -0.17240 0.00114  -0.12485 245 ASP A CA  
1636 C C   . ASP A 246 ? 0.65438 0.77129 0.56974 -0.17678 -0.01220 -0.12290 245 ASP A C   
1637 O O   . ASP A 246 ? 0.62380 0.77172 0.56194 -0.17108 -0.01660 -0.11552 245 ASP A O   
1638 C CB  . ASP A 246 ? 0.69534 0.73991 0.58702 -0.19387 0.00580  -0.13265 245 ASP A CB  
1639 C CG  . ASP A 246 ? 0.75062 0.75230 0.63811 -0.18692 0.01898  -0.13142 245 ASP A CG  
1640 O OD1 . ASP A 246 ? 0.68101 0.67723 0.57929 -0.16626 0.02360  -0.12408 245 ASP A OD1 
1641 O OD2 . ASP A 246 ? 0.77394 0.74751 0.64697 -0.20243 0.02454  -0.13731 245 ASP A OD2 
1642 N N   . GLU A 247 ? 0.67028 0.79468 0.56824 -0.18601 -0.01856 -0.12912 246 GLU A N   
1643 C CA  . GLU A 247 ? 0.63024 0.80303 0.53720 -0.19037 -0.03201 -0.12663 246 GLU A CA  
1644 C C   . GLU A 247 ? 0.59065 0.78879 0.51592 -0.16628 -0.03600 -0.11555 246 GLU A C   
1645 O O   . GLU A 247 ? 0.56193 0.80218 0.50493 -0.16365 -0.04464 -0.10967 246 GLU A O   
1646 C CB  . GLU A 247 ? 0.73840 0.91148 0.61978 -0.20463 -0.03822 -0.13535 246 GLU A CB  
1647 C CG  . GLU A 247 ? 0.81787 0.95028 0.67224 -0.22573 -0.03151 -0.14803 246 GLU A CG  
1648 C CD  . GLU A 247 ? 0.95568 1.03837 0.79043 -0.21422 -0.01877 -0.15165 246 GLU A CD  
1649 O OE1 . GLU A 247 ? 1.03624 1.11871 0.86103 -0.20249 -0.01973 -0.15067 246 GLU A OE1 
1650 O OE2 . GLU A 247 ? 0.94442 0.98947 0.77415 -0.21608 -0.00743 -0.15457 246 GLU A OE2 
1651 N N   . GLU A 248 ? 0.61621 0.78907 0.53707 -0.14859 -0.02937 -0.11231 247 GLU A N   
1652 C CA  . GLU A 248 ? 0.55905 0.74891 0.49477 -0.12668 -0.03207 -0.10191 247 GLU A CA  
1653 C C   . GLU A 248 ? 0.55825 0.75583 0.51744 -0.11799 -0.02929 -0.09528 247 GLU A C   
1654 O O   . GLU A 248 ? 0.55317 0.77847 0.52767 -0.10565 -0.03460 -0.08776 247 GLU A O   
1655 C CB  . GLU A 248 ? 0.59211 0.75242 0.51567 -0.11327 -0.02538 -0.10037 247 GLU A CB  
1656 C CG  . GLU A 248 ? 0.58965 0.74476 0.48873 -0.11881 -0.02807 -0.10570 247 GLU A CG  
1657 C CD  . GLU A 248 ? 0.63400 0.75704 0.52008 -0.10790 -0.01872 -0.10502 247 GLU A CD  
1658 O OE1 . GLU A 248 ? 0.61485 0.71235 0.50619 -0.10264 -0.00851 -0.10426 247 GLU A OE1 
1659 O OE2 . GLU A 248 ? 0.77349 0.89876 0.64423 -0.10456 -0.02154 -0.10458 247 GLU A OE2 
1660 N N   . ILE A 249 ? 0.56969 0.74190 0.53036 -0.12351 -0.02069 -0.09775 248 ILE A N   
1661 C CA  . ILE A 249 ? 0.51967 0.69740 0.50002 -0.11606 -0.01775 -0.09164 248 ILE A CA  
1662 C C   . ILE A 249 ? 0.52435 0.74228 0.51973 -0.12288 -0.02476 -0.08982 248 ILE A C   
1663 O O   . ILE A 249 ? 0.48535 0.72521 0.49712 -0.10984 -0.02688 -0.08283 248 ILE A O   
1664 C CB  . ILE A 249 ? 0.53364 0.67688 0.51054 -0.12180 -0.00763 -0.09413 248 ILE A CB  
1665 C CG1 . ILE A 249 ? 0.50797 0.61666 0.47356 -0.11186 -0.00007 -0.09425 248 ILE A CG1 
1666 C CG2 . ILE A 249 ? 0.49066 0.64160 0.48610 -0.11588 -0.00533 -0.08782 248 ILE A CG2 
1667 C CD1 . ILE A 249 ? 0.56516 0.63988 0.52613 -0.11537 0.01012  -0.09595 248 ILE A CD1 
1668 N N   . ILE A 250 ? 0.50565 0.73410 0.49496 -0.14378 -0.02810 -0.09615 249 ILE A N   
1669 C CA  . ILE A 250 ? 0.55972 0.83074 0.56494 -0.15241 -0.03442 -0.09400 249 ILE A CA  
1670 C C   . ILE A 250 ? 0.57798 0.89073 0.58787 -0.14753 -0.04555 -0.09096 249 ILE A C   
1671 O O   . ILE A 250 ? 0.56175 0.91685 0.58826 -0.15035 -0.05108 -0.08726 249 ILE A O   
1672 C CB  . ILE A 250 ? 0.58026 0.84679 0.57799 -0.17974 -0.03346 -0.10141 249 ILE A CB  
1673 C CG1 . ILE A 250 ? 0.57229 0.83560 0.54889 -0.19564 -0.03916 -0.10986 249 ILE A CG1 
1674 C CG2 . ILE A 250 ? 0.58464 0.80586 0.57492 -0.18333 -0.02201 -0.10368 249 ILE A CG2 
1675 C CD1 . ILE A 250 ? 0.65271 0.90736 0.61790 -0.22488 -0.03853 -0.11823 249 ILE A CD1 
1676 N N   . GLY A 251 ? 0.52689 0.83039 0.52284 -0.13943 -0.04867 -0.09151 250 GLY A N   
1677 C CA  . GLY A 251 ? 0.54726 0.88929 0.54466 -0.13566 -0.05990 -0.08818 250 GLY A CA  
1678 C C   . GLY A 251 ? 0.57686 0.95103 0.59493 -0.11400 -0.06307 -0.07755 250 GLY A C   
1679 O O   . GLY A 251 ? 0.61896 1.03871 0.64829 -0.11390 -0.07177 -0.07349 250 GLY A O   
1680 N N   . GLY A 252 ? 0.52755 0.87878 0.55014 -0.09528 -0.05606 -0.07282 251 GLY A N   
1681 C CA  . GLY A 252 ? 0.58998 0.96370 0.62817 -0.07377 -0.05757 -0.06364 251 GLY A CA  
1682 C C   . GLY A 252 ? 0.67789 1.05573 0.70930 -0.05536 -0.06274 -0.05738 251 GLY A C   
1683 O O   . GLY A 252 ? 0.60939 1.01389 0.65235 -0.03854 -0.06610 -0.04961 251 GLY A O   
1684 N N   . GLN A 253 ? 0.56353 0.91511 0.57557 -0.05724 -0.06280 -0.06005 252 GLN A N   
1685 C CA  . GLN A 253 ? 0.48717 0.83773 0.48979 -0.04065 -0.06687 -0.05348 252 GLN A CA  
1686 C C   . GLN A 253 ? 0.53470 0.83959 0.52574 -0.03292 -0.05857 -0.05325 252 GLN A C   
1687 O O   . GLN A 253 ? 0.56144 0.83854 0.54140 -0.04492 -0.05310 -0.06009 252 GLN A O   
1688 C CB  . GLN A 253 ? 0.54184 0.90995 0.53031 -0.05074 -0.07587 -0.05567 252 GLN A CB  
1689 N N   . VAL A 254 ? 0.46467 0.76194 0.45789 -0.01299 -0.05730 -0.04520 253 VAL A N   
1690 C CA  . VAL A 254 ? 0.44401 0.70203 0.42786 -0.00572 -0.05016 -0.04347 253 VAL A CA  
1691 C C   . VAL A 254 ? 0.50353 0.75865 0.47299 0.00557  -0.05420 -0.03684 253 VAL A C   
1692 O O   . VAL A 254 ? 0.46349 0.73104 0.43586 0.02187  -0.05812 -0.02871 253 VAL A O   
1693 C CB  . VAL A 254 ? 0.47543 0.72081 0.47067 0.00542  -0.04466 -0.04003 253 VAL A CB  
1694 C CG1 . VAL A 254 ? 0.45689 0.66427 0.44303 0.00982  -0.03805 -0.03823 253 VAL A CG1 
1695 C CG2 . VAL A 254 ? 0.47219 0.72342 0.48084 -0.00554 -0.04111 -0.04553 253 VAL A CG2 
1696 N N   . PHE A 255 ? 0.43287 0.67060 0.38544 -0.00238 -0.05262 -0.03998 254 PHE A N   
1697 C CA  . PHE A 255 ? 0.45465 0.68447 0.39074 0.00681  -0.05487 -0.03350 254 PHE A CA  
1698 C C   . PHE A 255 ? 0.49512 0.68889 0.42672 0.01370  -0.04620 -0.02995 254 PHE A C   
1699 O O   . PHE A 255 ? 0.43795 0.61067 0.37064 0.00511  -0.03841 -0.03534 254 PHE A O   
1700 C CB  . PHE A 255 ? 0.46263 0.69483 0.38068 -0.00624 -0.05754 -0.03898 254 PHE A CB  
1701 C CG  . PHE A 255 ? 0.55351 0.77345 0.45178 0.00149  -0.05812 -0.03261 254 PHE A CG  
1702 C CD1 . PHE A 255 ? 0.51174 0.75429 0.40382 0.01159  -0.06756 -0.02438 254 PHE A CD1 
1703 C CD2 . PHE A 255 ? 0.53836 0.72579 0.42425 -0.00104 -0.04893 -0.03400 254 PHE A CD2 
1704 C CE1 . PHE A 255 ? 0.50979 0.73990 0.38190 0.01845  -0.06791 -0.01761 254 PHE A CE1 
1705 C CE2 . PHE A 255 ? 0.55916 0.73592 0.42627 0.00513  -0.04869 -0.02757 254 PHE A CE2 
1706 C CZ  . PHE A 255 ? 0.53818 0.73490 0.39742 0.01450  -0.05824 -0.01939 254 PHE A CZ  
1707 N N   . PHE A 256 ? 0.46155 0.64846 0.38794 0.02897  -0.04754 -0.02039 255 PHE A N   
1708 C CA  . PHE A 256 ? 0.52164 0.67572 0.44320 0.03421  -0.04020 -0.01604 255 PHE A CA  
1709 C C   . PHE A 256 ? 0.48848 0.62865 0.39011 0.03265  -0.03852 -0.01287 255 PHE A C   
1710 O O   . PHE A 256 ? 0.56289 0.71090 0.45247 0.04078  -0.04416 -0.00601 255 PHE A O   
1711 C CB  . PHE A 256 ? 0.47752 0.62639 0.40313 0.05049  -0.04136 -0.00802 255 PHE A CB  
1712 C CG  . PHE A 256 ? 0.46111 0.61083 0.40375 0.05087  -0.03876 -0.01165 255 PHE A CG  
1713 C CD1 . PHE A 256 ? 0.49614 0.62013 0.44202 0.04725  -0.03176 -0.01305 255 PHE A CD1 
1714 C CD2 . PHE A 256 ? 0.48421 0.66289 0.43967 0.05402  -0.04331 -0.01339 255 PHE A CD2 
1715 C CE1 . PHE A 256 ? 0.48671 0.61148 0.44617 0.04715  -0.02968 -0.01631 255 PHE A CE1 
1716 C CE2 . PHE A 256 ? 0.49965 0.67912 0.46923 0.05414  -0.04016 -0.01661 255 PHE A CE2 
1717 C CZ  . PHE A 256 ? 0.46731 0.61868 0.43779 0.05079  -0.03350 -0.01820 255 PHE A CZ  
1718 N N   . ARG A 257 ? 0.53445 0.65523 0.43252 0.02286  -0.03035 -0.01733 256 ARG A N   
1719 C CA  . ARG A 257 ? 0.59604 0.70337 0.47554 0.02009  -0.02642 -0.01527 256 ARG A CA  
1720 C C   . ARG A 257 ? 0.55811 0.64295 0.43166 0.02803  -0.02207 -0.00542 256 ARG A C   
1721 O O   . ARG A 257 ? 0.59035 0.66457 0.44788 0.02689  -0.01849 -0.00164 256 ARG A O   
1722 C CB  . ARG A 257 ? 0.61997 0.71734 0.49862 0.00739  -0.01817 -0.02432 256 ARG A CB  
1723 C CG  . ARG A 257 ? 0.59361 0.67461 0.48743 0.00583  -0.00997 -0.02516 256 ARG A CG  
1724 C CD  . ARG A 257 ? 0.61819 0.69310 0.51346 -0.00469 -0.00263 -0.03439 256 ARG A CD  
1725 N NE  . ARG A 257 ? 0.63915 0.72779 0.54199 -0.01136 -0.00687 -0.04248 256 ARG A NE  
1726 C CZ  . ARG A 257 ? 0.60614 0.68986 0.50612 -0.02137 -0.00233 -0.05154 256 ARG A CZ  
1727 N NH1 . ARG A 257 ? 0.65131 0.71739 0.54124 -0.02413 0.00715  -0.05416 256 ARG A NH1 
1728 N NH2 . ARG A 257 ? 0.56633 0.66241 0.47283 -0.02867 -0.00673 -0.05790 256 ARG A NH2 
1729 N N   . GLN A 258 ? 0.53857 0.61493 0.42305 0.03493  -0.02191 -0.00142 257 GLN A N   
1730 C CA  . GLN A 258 ? 0.56344 0.61616 0.44118 0.04066  -0.01836 0.00764  257 GLN A CA  
1731 C C   . GLN A 258 ? 0.53456 0.58665 0.41257 0.05443  -0.02416 0.01388  257 GLN A C   
1732 O O   . GLN A 258 ? 0.50721 0.57799 0.39604 0.05912  -0.02924 0.01050  257 GLN A O   
1733 C CB  . GLN A 258 ? 0.55948 0.59540 0.44816 0.03327  -0.01039 0.00573  257 GLN A CB  
1734 C CG  . GLN A 258 ? 0.72364 0.75416 0.60850 0.02351  -0.00232 0.00362  257 GLN A CG  
1735 C CD  . GLN A 258 ? 0.71051 0.72472 0.58032 0.02430  0.00188  0.01290  257 GLN A CD  
1736 O OE1 . GLN A 258 ? 0.70496 0.70281 0.57496 0.02614  0.00312  0.01971  257 GLN A OE1 
1737 N NE2 . GLN A 258 ? 0.85646 0.87395 0.71135 0.02194  0.00429  0.01314  257 GLN A NE2 
1738 N N   . ARG A 259 ? 0.50727 0.53679 0.37232 0.06107  -0.02261 0.02334  258 ARG A N   
1739 C CA  . ARG A 259 ? 0.52386 0.54393 0.38639 0.07518  -0.02597 0.02938  258 ARG A CA  
1740 C C   . ARG A 259 ? 0.51531 0.52862 0.39317 0.07339  -0.02360 0.02390  258 ARG A C   
1741 O O   . ARG A 259 ? 0.50405 0.49836 0.38440 0.06428  -0.01803 0.02294  258 ARG A O   
1742 C CB  . ARG A 259 ? 0.54687 0.53733 0.38954 0.08034  -0.02354 0.04045  258 ARG A CB  
1743 C CG  . ARG A 259 ? 0.62696 0.59566 0.46486 0.09304  -0.02423 0.04559  258 ARG A CG  
1744 C CD  . ARG A 259 ? 0.58453 0.57266 0.42274 0.11082  -0.03118 0.04814  258 ARG A CD  
1745 N NE  . ARG A 259 ? 0.58626 0.55746 0.42441 0.12325  -0.03047 0.04939  258 ARG A NE  
1746 C CZ  . ARG A 259 ? 0.64890 0.62687 0.48293 0.14308  -0.03443 0.05479  258 ARG A CZ  
1747 N NH1 . ARG A 259 ? 0.59185 0.59542 0.42245 0.15253  -0.04061 0.06050  258 ARG A NH1 
1748 N NH2 . ARG A 259 ? 0.60776 0.56677 0.44020 0.15424  -0.03204 0.05469  258 ARG A NH2 
1749 N N   . VAL A 260 ? 0.48585 0.51713 0.37419 0.08155  -0.02783 0.02059  259 VAL A N   
1750 C CA  . VAL A 260 ? 0.52907 0.55636 0.43030 0.08109  -0.02587 0.01531  259 VAL A CA  
1751 C C   . VAL A 260 ? 0.54247 0.56942 0.44047 0.09914  -0.02882 0.01923  259 VAL A C   
1752 O O   . VAL A 260 ? 0.54357 0.59472 0.44232 0.10965  -0.03398 0.02184  259 VAL A O   
1753 C CB  . VAL A 260 ? 0.46659 0.51972 0.38637 0.07113  -0.02617 0.00573  259 VAL A CB  
1754 C CG1 . VAL A 260 ? 0.49836 0.54854 0.42965 0.07196  -0.02439 0.00135  259 VAL A CG1 
1755 C CG2 . VAL A 260 ? 0.43625 0.48653 0.35796 0.05552  -0.02190 0.00183  259 VAL A CG2 
1756 N N   . SER A 261 ? 0.54569 0.54603 0.43954 0.10291  -0.02548 0.01966  260 SER A N   
1757 C CA  . SER A 261 ? 0.57858 0.57242 0.46639 0.12175  -0.02637 0.02301  260 SER A CA  
1758 C C   . SER A 261 ? 0.50849 0.53993 0.41344 0.12884  -0.02933 0.01857  260 SER A C   
1759 O O   . SER A 261 ? 0.51357 0.56659 0.43489 0.11641  -0.02939 0.01112  260 SER A O   
1760 C CB  . SER A 261 ? 0.58399 0.54177 0.46378 0.12108  -0.02170 0.02136  260 SER A CB  
1761 O OG  . SER A 261 ? 0.53687 0.50410 0.43214 0.11068  -0.02002 0.01251  260 SER A OG  
1762 N N   . SEP A 262 ? 0.51240 0.55190 0.41339 0.14907  -0.03136 0.02394  261 SEP A N   
1763 C CA  . SEP A 262 ? 0.54010 0.61910 0.45813 0.15737  -0.03385 0.02136  261 SEP A CA  
1764 C CB  . SEP A 262 ? 0.54776 0.63208 0.45846 0.18330  -0.03543 0.03011  261 SEP A CB  
1765 O OG  . SEP A 262 ? 0.65038 0.74309 0.55214 0.18846  -0.04087 0.03871  261 SEP A OG  
1766 C C   . SEP A 262 ? 0.55369 0.63265 0.48347 0.15180  -0.02941 0.01278  261 SEP A C   
1767 O O   . SEP A 262 ? 0.48450 0.59742 0.43253 0.14586  -0.03067 0.00763  261 SEP A O   
1768 P P   . SEP A 262 ? 0.70873 0.75477 0.58337 0.20248  -0.03819 0.04859  261 SEP A P   
1769 O O1P . SEP A 262 ? 0.65757 0.69171 0.52580 0.22921  -0.03459 0.05290  261 SEP A O1P 
1770 O O2P . SEP A 262 ? 0.61969 0.67719 0.48350 0.20745  -0.04457 0.05904  261 SEP A O2P 
1771 O O3P . SEP A 262 ? 0.65118 0.65045 0.51409 0.18466  -0.03232 0.04425  261 SEP A O3P 
1772 N N   . GLU A 263 ? 0.54258 0.58280 0.46045 0.15240  -0.02437 0.01140  262 GLU A N   
1773 C CA  . GLU A 263 ? 0.56452 0.60131 0.48994 0.14690  -0.02032 0.00361  262 GLU A CA  
1774 C C   . GLU A 263 ? 0.52536 0.57498 0.46537 0.12438  -0.02070 -0.00296 262 GLU A C   
1775 O O   . GLU A 263 ? 0.47957 0.55180 0.43447 0.11965  -0.01988 -0.00842 262 GLU A O   
1776 C CB  . GLU A 263 ? 0.58998 0.57965 0.49595 0.14974  -0.01578 0.00330  262 GLU A CB  
1777 C CG  . GLU A 263 ? 0.68753 0.65908 0.57714 0.17402  -0.01336 0.00824  262 GLU A CG  
1778 C CD  . GLU A 263 ? 0.79302 0.75365 0.66865 0.18490  -0.01591 0.01829  262 GLU A CD  
1779 O OE1 . GLU A 263 ? 0.71323 0.67392 0.58852 0.17174  -0.01895 0.02099  262 GLU A OE1 
1780 O OE2 . GLU A 263 ? 0.90751 0.85930 0.77159 0.20770  -0.01436 0.02398  262 GLU A OE2 
1781 N N   . CYS A 264 ? 0.50866 0.54367 0.44381 0.11126  -0.02127 -0.00178 263 CYS A N   
1782 C CA  . CYS A 264 ? 0.48593 0.53086 0.43359 0.09218  -0.02071 -0.00718 263 CYS A CA  
1783 C C   . CYS A 264 ? 0.48384 0.56682 0.44561 0.08812  -0.02389 -0.00966 263 CYS A C   
1784 O O   . CYS A 264 ? 0.43587 0.53344 0.41079 0.07732  -0.02282 -0.01546 263 CYS A O   
1785 C CB  . CYS A 264 ? 0.47615 0.49875 0.41529 0.08124  -0.01954 -0.00453 263 CYS A CB  
1786 S SG  . CYS A 264 ? 0.47910 0.50947 0.43211 0.06080  -0.01721 -0.01007 263 CYS A SG  
1787 N N   . GLN A 265 ? 0.45616 0.55474 0.41403 0.09586  -0.02810 -0.00506 264 GLN A N   
1788 C CA  . GLN A 265 ? 0.48051 0.61643 0.44992 0.09072  -0.03227 -0.00753 264 GLN A CA  
1789 C C   . GLN A 265 ? 0.45274 0.61575 0.43758 0.09375  -0.03219 -0.01103 264 GLN A C   
1790 O O   . GLN A 265 ? 0.41206 0.59751 0.40925 0.08103  -0.03293 -0.01633 264 GLN A O   
1791 C CB  . GLN A 265 ? 0.46893 0.61910 0.43027 0.10069  -0.03792 -0.00079 264 GLN A CB  
1792 C CG  . GLN A 265 ? 0.46033 0.59386 0.40732 0.09430  -0.03862 0.00221  264 GLN A CG  
1793 C CD  . GLN A 265 ? 0.50080 0.65909 0.44241 0.09993  -0.04562 0.00718  264 GLN A CD  
1794 O OE1 . GLN A 265 ? 0.51223 0.70505 0.46415 0.10507  -0.05057 0.00732  264 GLN A OE1 
1795 N NE2 . GLN A 265 ? 0.47702 0.62002 0.40255 0.09841  -0.04619 0.01172  264 GLN A NE2 
1796 N N   . HIS A 266 ? 0.42053 0.58075 0.40358 0.11059  -0.03059 -0.00801 265 HIS A N   
1797 C CA  . HIS A 266 ? 0.46243 0.64993 0.45979 0.11515  -0.02927 -0.01061 265 HIS A CA  
1798 C C   . HIS A 266 ? 0.44496 0.62558 0.45006 0.10045  -0.02486 -0.01778 265 HIS A C   
1799 O O   . HIS A 266 ? 0.41988 0.62847 0.43949 0.09192  -0.02493 -0.02143 265 HIS A O   
1800 C CB  . HIS A 266 ? 0.49455 0.67451 0.48509 0.13815  -0.02664 -0.00609 265 HIS A CB  
1801 C CG  . HIS A 266 ? 0.51094 0.71745 0.51504 0.14454  -0.02348 -0.00852 265 HIS A CG  
1802 N ND1 . HIS A 266 ? 0.50550 0.69649 0.50967 0.14071  -0.01756 -0.01397 265 HIS A ND1 
1803 C CD2 . HIS A 266 ? 0.51209 0.76192 0.53026 0.15418  -0.02523 -0.00573 265 HIS A CD2 
1804 C CE1 . HIS A 266 ? 0.48638 0.70821 0.50305 0.14801  -0.01499 -0.01463 265 HIS A CE1 
1805 N NE2 . HIS A 266 ? 0.48731 0.74638 0.51382 0.15618  -0.01941 -0.00955 265 HIS A NE2 
1806 N N   . LEU A 267 ? 0.43226 0.57638 0.42747 0.09663  -0.02125 -0.01922 266 LEU A N   
1807 C CA  . LEU A 267 ? 0.44466 0.58235 0.44634 0.08345  -0.01772 -0.02478 266 LEU A CA  
1808 C C   . LEU A 267 ? 0.43294 0.58449 0.44447 0.06564  -0.01894 -0.02813 266 LEU A C   
1809 O O   . LEU A 267 ? 0.38976 0.55624 0.41225 0.05689  -0.01726 -0.03193 266 LEU A O   
1810 C CB  . LEU A 267 ? 0.39890 0.49753 0.38797 0.08110  -0.01510 -0.02482 266 LEU A CB  
1811 C CG  . LEU A 267 ? 0.47993 0.57106 0.47448 0.06788  -0.01234 -0.02922 266 LEU A CG  
1812 C CD1 . LEU A 267 ? 0.38951 0.49593 0.39058 0.07193  -0.00970 -0.03228 266 LEU A CD1 
1813 C CD2 . LEU A 267 ? 0.43714 0.49335 0.41947 0.06423  -0.01123 -0.02837 266 LEU A CD2 
1814 N N   . ILE A 268 ? 0.42603 0.57110 0.43194 0.06036  -0.02123 -0.02667 267 ILE A N   
1815 C CA  . ILE A 268 ? 0.39438 0.54806 0.40577 0.04457  -0.02153 -0.03044 267 ILE A CA  
1816 C C   . ILE A 268 ? 0.37068 0.55963 0.39288 0.04054  -0.02437 -0.03293 267 ILE A C   
1817 O O   . ILE A 268 ? 0.37602 0.57277 0.40627 0.02771  -0.02255 -0.03744 267 ILE A O   
1818 C CB  . ILE A 268 ? 0.44489 0.58634 0.44552 0.04209  -0.02294 -0.02825 267 ILE A CB  
1819 C CG1 . ILE A 268 ? 0.43353 0.54242 0.42600 0.04159  -0.01933 -0.02588 267 ILE A CG1 
1820 C CG2 . ILE A 268 ? 0.40953 0.56125 0.41276 0.02766  -0.02313 -0.03296 267 ILE A CG2 
1821 C CD1 . ILE A 268 ? 0.39441 0.49109 0.37517 0.04082  -0.01969 -0.02233 267 ILE A CD1 
1822 N N   . ARG A 269 ? 0.38056 0.59187 0.40288 0.05099  -0.02899 -0.02937 268 ARG A N   
1823 C CA  . ARG A 269 ? 0.35621 0.60618 0.39005 0.04583  -0.03266 -0.03099 268 ARG A CA  
1824 C C   . ARG A 269 ? 0.40553 0.67097 0.45241 0.04523  -0.02911 -0.03292 268 ARG A C   
1825 O O   . ARG A 269 ? 0.37703 0.66590 0.43411 0.03228  -0.02972 -0.03628 268 ARG A O   
1826 C CB  . ARG A 269 ? 0.40029 0.67459 0.43278 0.05935  -0.03884 -0.02511 268 ARG A CB  
1827 C CG  . ARG A 269 ? 0.40779 0.67546 0.42754 0.05628  -0.04345 -0.02345 268 ARG A CG  
1828 C CD  . ARG A 269 ? 0.46735 0.76788 0.48775 0.06699  -0.05108 -0.01743 268 ARG A CD  
1829 N NE  . ARG A 269 ? 0.57088 0.86978 0.57857 0.06039  -0.05612 -0.01687 268 ARG A NE  
1830 C CZ  . ARG A 269 ? 0.52787 0.80691 0.52011 0.07092  -0.05717 -0.01083 268 ARG A CZ  
1831 N NH1 . ARG A 269 ? 0.55053 0.80805 0.53741 0.08842  -0.05394 -0.00474 268 ARG A NH1 
1832 N NH2 . ARG A 269 ? 0.52431 0.80305 0.50414 0.06306  -0.06116 -0.01103 268 ARG A NH2 
1833 N N   . TRP A 270 ? 0.36330 0.61437 0.40819 0.05805  -0.02504 -0.03103 269 TRP A N   
1834 C CA  . TRP A 270 ? 0.40353 0.66581 0.45813 0.05760  -0.02053 -0.03301 269 TRP A CA  
1835 C C   . TRP A 270 ? 0.39325 0.64338 0.45070 0.03901  -0.01729 -0.03785 269 TRP A C   
1836 O O   . TRP A 270 ? 0.39385 0.66524 0.46188 0.02915  -0.01584 -0.03999 269 TRP A O   
1837 C CB  . TRP A 270 ? 0.40704 0.64901 0.45368 0.07457  -0.01648 -0.03100 269 TRP A CB  
1838 C CG  . TRP A 270 ? 0.44889 0.70829 0.50372 0.07969  -0.01174 -0.03198 269 TRP A CG  
1839 C CD1 . TRP A 270 ? 0.39477 0.68946 0.46492 0.07146  -0.01092 -0.03315 269 TRP A CD1 
1840 C CD2 . TRP A 270 ? 0.42839 0.67001 0.47481 0.09357  -0.00654 -0.03197 269 TRP A CD2 
1841 N NE1 . TRP A 270 ? 0.45191 0.75392 0.52481 0.08025  -0.00501 -0.03330 269 TRP A NE1 
1842 C CE2 . TRP A 270 ? 0.44458 0.71348 0.50214 0.09435  -0.00219 -0.03306 269 TRP A CE2 
1843 C CE3 . TRP A 270 ? 0.48567 0.68967 0.51459 0.10437  -0.00488 -0.03141 269 TRP A CE3 
1844 C CZ2 . TRP A 270 ? 0.43826 0.69782 0.48913 0.10686  0.00415  -0.03401 269 TRP A CZ2 
1845 C CZ3 . TRP A 270 ? 0.47556 0.66815 0.49682 0.11570  0.00081  -0.03292 269 TRP A CZ3 
1846 C CH2 . TRP A 270 ? 0.46449 0.68474 0.49632 0.11757  0.00547  -0.03440 269 TRP A CH2 
1847 N N   . CYS A 271 ? 0.38553 0.60209 0.43368 0.03414  -0.01587 -0.03882 270 CYS A N   
1848 C CA  . CYS A 271 ? 0.40254 0.60631 0.45286 0.01879  -0.01265 -0.04215 270 CYS A CA  
1849 C C   . CYS A 271 ? 0.39226 0.61078 0.44702 0.00366  -0.01419 -0.04533 270 CYS A C   
1850 O O   . CYS A 271 ? 0.36036 0.57772 0.41938 -0.00870 -0.01108 -0.04791 270 CYS A O   
1851 C CB  . CYS A 271 ? 0.40245 0.57235 0.44341 0.01775  -0.01122 -0.04141 270 CYS A CB  
1852 S SG  . CYS A 271 ? 0.39686 0.54319 0.43028 0.02890  -0.00920 -0.03909 270 CYS A SG  
1853 N N   . LEU A 272 ? 0.33474 0.56506 0.38647 0.00389  -0.01896 -0.04515 271 LEU A N   
1854 C CA  . LEU A 272 ? 0.36671 0.60829 0.41870 -0.01169 -0.02105 -0.04918 271 LEU A CA  
1855 C C   . LEU A 272 ? 0.35336 0.63513 0.41583 -0.01539 -0.02500 -0.04932 271 LEU A C   
1856 O O   . LEU A 272 ? 0.36972 0.66684 0.43051 -0.02610 -0.02945 -0.05187 271 LEU A O   
1857 C CB  . LEU A 272 ? 0.39479 0.62459 0.43473 -0.01184 -0.02401 -0.04948 271 LEU A CB  
1858 C CG  . LEU A 272 ? 0.41103 0.60473 0.44205 -0.01037 -0.01947 -0.04903 271 LEU A CG  
1859 C CD1 . LEU A 272 ? 0.37502 0.55950 0.39351 -0.01152 -0.02132 -0.04937 271 LEU A CD1 
1860 C CD2 . LEU A 272 ? 0.35163 0.52894 0.38522 -0.02166 -0.01359 -0.05235 271 LEU A CD2 
1861 N N   . ALA A 273 ? 0.40067 0.70109 0.47353 -0.00727 -0.02331 -0.04664 272 ALA A N   
1862 C CA  . ALA A 273 ? 0.37612 0.71898 0.46194 -0.01193 -0.02596 -0.04608 272 ALA A CA  
1863 C C   . ALA A 273 ? 0.38752 0.73371 0.47581 -0.03556 -0.02473 -0.05109 272 ALA A C   
1864 O O   . ALA A 273 ? 0.39585 0.71675 0.48119 -0.04344 -0.01896 -0.05332 272 ALA A O   
1865 C CB  . ALA A 273 ? 0.37650 0.73564 0.47223 0.00140  -0.02194 -0.04250 272 ALA A CB  
1866 N N   . LEU A 274 ? 0.33700 0.71389 0.42954 -0.04728 -0.03046 -0.05251 273 LEU A N   
1867 C CA  . LEU A 274 ? 0.39089 0.76869 0.48282 -0.07198 -0.02966 -0.05783 273 LEU A CA  
1868 C C   . LEU A 274 ? 0.39230 0.77995 0.49534 -0.07852 -0.02358 -0.05679 273 LEU A C   
1869 O O   . LEU A 274 ? 0.42080 0.78468 0.51856 -0.09328 -0.01860 -0.06006 273 LEU A O   
1870 C CB  . LEU A 274 ? 0.39047 0.80341 0.48455 -0.08426 -0.03816 -0.05941 273 LEU A CB  
1871 C CG  . LEU A 274 ? 0.43377 0.83403 0.51256 -0.08368 -0.04409 -0.06177 273 LEU A CG  
1872 C CD1 . LEU A 274 ? 0.43102 0.87151 0.51222 -0.09607 -0.05374 -0.06276 273 LEU A CD1 
1873 C CD2 . LEU A 274 ? 0.44888 0.80162 0.51009 -0.09496 -0.03906 -0.06837 273 LEU A CD2 
1874 N N   . ARG A 275 ? 0.39732 0.81917 0.51473 -0.06697 -0.02325 -0.05179 274 ARG A N   
1875 C CA  . ARG A 275 ? 0.42082 0.85347 0.54801 -0.07166 -0.01657 -0.05017 274 ARG A CA  
1876 C C   . ARG A 275 ? 0.42863 0.82465 0.54876 -0.05938 -0.00967 -0.04919 274 ARG A C   
1877 O O   . ARG A 275 ? 0.41551 0.80317 0.53269 -0.03887 -0.00986 -0.04681 274 ARG A O   
1878 C CB  . ARG A 275 ? 0.43685 0.92115 0.58182 -0.06226 -0.01753 -0.04502 274 ARG A CB  
1879 N N   . PRO A 276 ? 0.41385 0.78651 0.52980 -0.07164 -0.00386 -0.05065 275 PRO A N   
1880 C CA  . PRO A 276 ? 0.45788 0.79761 0.56662 -0.06082 0.00146  -0.04927 275 PRO A CA  
1881 C C   . PRO A 276 ? 0.45426 0.80911 0.56842 -0.04237 0.00442  -0.04565 275 PRO A C   
1882 O O   . PRO A 276 ? 0.41167 0.74254 0.51773 -0.02761 0.00531  -0.04499 275 PRO A O   
1883 C CB  . PRO A 276 ? 0.42380 0.74699 0.52968 -0.07853 0.00687  -0.04994 275 PRO A CB  
1884 C CG  . PRO A 276 ? 0.47825 0.80644 0.58276 -0.09860 0.00389  -0.05371 275 PRO A CG  
1885 C CD  . PRO A 276 ? 0.41267 0.78379 0.52765 -0.09643 -0.00236 -0.05348 275 PRO A CD  
1886 N N   . SER A 277 ? 0.45061 0.84464 0.57748 -0.04307 0.00640  -0.04340 276 SER A N   
1887 C CA  . SER A 277 ? 0.45649 0.86418 0.58692 -0.02441 0.01092  -0.04040 276 SER A CA  
1888 C C   . SER A 277 ? 0.43560 0.84730 0.56431 -0.00210 0.00726  -0.03909 276 SER A C   
1889 O O   . SER A 277 ? 0.46216 0.86989 0.58725 0.01618  0.01138  -0.03767 276 SER A O   
1890 C CB  . SER A 277 ? 0.44290 0.89557 0.58871 -0.03037 0.01490  -0.03767 276 SER A CB  
1891 O OG  . SER A 277 ? 0.47406 0.96570 0.63244 -0.03629 0.00906  -0.03679 276 SER A OG  
1892 N N   . ASP A 278 ? 0.43431 0.85160 0.56331 -0.00311 -0.00006 -0.03948 277 ASP A N   
1893 C CA  . ASP A 278 ? 0.43915 0.85524 0.56394 0.01780  -0.00376 -0.03725 277 ASP A CA  
1894 C C   . ASP A 278 ? 0.41907 0.78667 0.52671 0.02494  -0.00401 -0.03880 277 ASP A C   
1895 O O   . ASP A 278 ? 0.44726 0.80639 0.54827 0.04289  -0.00570 -0.03662 277 ASP A O   
1896 C CB  . ASP A 278 ? 0.39691 0.83999 0.52756 0.01369  -0.01203 -0.03614 277 ASP A CB  
1897 C CG  . ASP A 278 ? 0.46823 0.96744 0.61767 0.01231  -0.01308 -0.03274 277 ASP A CG  
1898 O OD1 . ASP A 278 ? 0.46183 0.97990 0.61955 0.02223  -0.00664 -0.03015 277 ASP A OD1 
1899 O OD2 . ASP A 278 ? 0.44170 0.96750 0.59727 0.00112  -0.02032 -0.03256 277 ASP A OD2 
1900 N N   . ARG A 279 ? 0.41446 0.75087 0.51486 0.01148  -0.00226 -0.04180 278 ARG A N   
1901 C CA  . ARG A 279 ? 0.36592 0.66100 0.45236 0.01649  -0.00262 -0.04257 278 ARG A CA  
1902 C C   . ARG A 279 ? 0.43828 0.71615 0.51755 0.02969  0.00203  -0.04186 278 ARG A C   
1903 O O   . ARG A 279 ? 0.44844 0.73893 0.53196 0.02995  0.00693  -0.04178 278 ARG A O   
1904 C CB  . ARG A 279 ? 0.37633 0.64750 0.45884 -0.00097 -0.00201 -0.04512 278 ARG A CB  
1905 C CG  . ARG A 279 ? 0.36929 0.64750 0.45292 -0.01371 -0.00623 -0.04722 278 ARG A CG  
1906 C CD  . ARG A 279 ? 0.37376 0.62996 0.45351 -0.03063 -0.00365 -0.04992 278 ARG A CD  
1907 N NE  . ARG A 279 ? 0.39843 0.66701 0.47912 -0.04554 -0.00646 -0.05310 278 ARG A NE  
1908 C CZ  . ARG A 279 ? 0.41764 0.67514 0.49584 -0.06262 -0.00372 -0.05595 278 ARG A CZ  
1909 N NH1 . ARG A 279 ? 0.37349 0.60798 0.44918 -0.06590 0.00182  -0.05498 278 ARG A NH1 
1910 N NH2 . ARG A 279 ? 0.40858 0.67757 0.48540 -0.07690 -0.00674 -0.05966 278 ARG A NH2 
1911 N N   . PRO A 280 ? 0.43056 0.67903 0.49743 0.03974  0.00079  -0.04148 279 PRO A N   
1912 C CA  . PRO A 280 ? 0.38623 0.61468 0.44272 0.05083  0.00465  -0.04177 279 PRO A CA  
1913 C C   . PRO A 280 ? 0.43467 0.64366 0.48736 0.03930  0.00729  -0.04331 279 PRO A C   
1914 O O   . PRO A 280 ? 0.42375 0.62425 0.47897 0.02535  0.00587  -0.04351 279 PRO A O   
1915 C CB  . PRO A 280 ? 0.40110 0.60231 0.44467 0.06084  0.00157  -0.04069 279 PRO A CB  
1916 C CG  . PRO A 280 ? 0.45439 0.65114 0.50047 0.04898  -0.00279 -0.04038 279 PRO A CG  
1917 C CD  . PRO A 280 ? 0.41863 0.64964 0.47869 0.04004  -0.00397 -0.04084 279 PRO A CD  
1918 N N   . THR A 281 ? 0.41936 0.62110 0.46464 0.04634  0.01144  -0.04418 280 THR A N   
1919 C CA  . THR A 281 ? 0.43499 0.61500 0.47285 0.03806  0.01284  -0.04494 280 THR A CA  
1920 C C   . THR A 281 ? 0.45968 0.60610 0.48504 0.03919  0.00923  -0.04507 280 THR A C   
1921 O O   . THR A 281 ? 0.47437 0.61170 0.49444 0.04784  0.00685  -0.04476 280 THR A O   
1922 C CB  . THR A 281 ? 0.44203 0.62577 0.47348 0.04465  0.01840  -0.04624 280 THR A CB  
1923 O OG1 . THR A 281 ? 0.42593 0.59509 0.44381 0.06112  0.01943  -0.04799 280 THR A OG1 
1924 C CG2 . THR A 281 ? 0.45228 0.67325 0.49722 0.04418  0.02283  -0.04531 280 THR A CG2 
1925 N N   . PHE A 282 ? 0.44897 0.57799 0.46956 0.02998  0.00875  -0.04473 281 PHE A N   
1926 C CA  . PHE A 282 ? 0.48513 0.58570 0.49491 0.02906  0.00522  -0.04435 281 PHE A CA  
1927 C C   . PHE A 282 ? 0.48573 0.56935 0.47918 0.04146  0.00580  -0.04675 281 PHE A C   
1928 O O   . PHE A 282 ? 0.45012 0.51432 0.43540 0.04441  0.00302  -0.04628 281 PHE A O   
1929 C CB  . PHE A 282 ? 0.47838 0.56865 0.48658 0.01800  0.00434  -0.04279 281 PHE A CB  
1930 C CG  . PHE A 282 ? 0.48840 0.58727 0.50970 0.00713  0.00421  -0.03982 281 PHE A CG  
1931 C CD1 . PHE A 282 ? 0.57358 0.67533 0.60244 0.00521  0.00294  -0.03914 281 PHE A CD1 
1932 C CD2 . PHE A 282 ? 0.60717 0.70899 0.63094 -0.00065 0.00581  -0.03761 281 PHE A CD2 
1933 C CE1 . PHE A 282 ? 0.52970 0.63504 0.56750 -0.00408 0.00387  -0.03726 281 PHE A CE1 
1934 C CE2 . PHE A 282 ? 0.57579 0.68097 0.60925 -0.00936 0.00660  -0.03469 281 PHE A CE2 
1935 C CZ  . PHE A 282 ? 0.52172 0.62766 0.56175 -0.01095 0.00594  -0.03501 281 PHE A CZ  
1936 N N   . GLU A 283 ? 0.46971 0.55888 0.45677 0.04897  0.01020  -0.04929 282 GLU A N   
1937 C CA  . GLU A 283 ? 0.49065 0.56071 0.45935 0.06251  0.01225  -0.05234 282 GLU A CA  
1938 C C   . GLU A 283 ? 0.45240 0.52595 0.42221 0.07614  0.01225  -0.05109 282 GLU A C   
1939 O O   . GLU A 283 ? 0.50023 0.54696 0.45465 0.08331  0.01115  -0.05162 282 GLU A O   
1940 C CB  . GLU A 283 ? 0.47534 0.55428 0.43762 0.06935  0.01857  -0.05536 282 GLU A CB  
1941 C CG  . GLU A 283 ? 0.49702 0.55515 0.43825 0.08592  0.02257  -0.05929 282 GLU A CG  
1942 C CD  . GLU A 283 ? 0.68219 0.75009 0.61612 0.09379  0.03028  -0.06258 282 GLU A CD  
1943 O OE1 . GLU A 283 ? 0.61644 0.71471 0.56556 0.08843  0.03301  -0.06072 282 GLU A OE1 
1944 O OE2 . GLU A 283 ? 0.67156 0.71515 0.58294 0.10514  0.03423  -0.06711 282 GLU A OE2 
1945 N N   . GLU A 284 ? 0.45857 0.56489 0.44562 0.07919  0.01315  -0.04894 283 GLU A N   
1946 C CA  . GLU A 284 ? 0.49216 0.60671 0.48141 0.09244  0.01220  -0.04656 283 GLU A CA  
1947 C C   . GLU A 284 ? 0.47035 0.56702 0.45708 0.08722  0.00657  -0.04410 283 GLU A C   
1948 O O   . GLU A 284 ? 0.49012 0.57462 0.46780 0.09919  0.00567  -0.04214 283 GLU A O   
1949 C CB  . GLU A 284 ? 0.46063 0.61856 0.47008 0.09347  0.01310  -0.04453 283 GLU A CB  
1950 C CG  . GLU A 284 ? 0.50550 0.68564 0.51768 0.10365  0.01990  -0.04564 283 GLU A CG  
1951 C CD  . GLU A 284 ? 0.43819 0.66477 0.47235 0.10051  0.02035  -0.04314 283 GLU A CD  
1952 O OE1 . GLU A 284 ? 0.47862 0.71619 0.52409 0.08241  0.01756  -0.04290 283 GLU A OE1 
1953 O OE2 . GLU A 284 ? 0.50172 0.75369 0.54142 0.11606  0.02359  -0.04119 283 GLU A OE2 
1954 N N   . ILE A 285 ? 0.44892 0.54316 0.44263 0.07047  0.00345  -0.04360 284 ILE A N   
1955 C CA  . ILE A 285 ? 0.48465 0.56253 0.47565 0.06529  -0.00068 -0.04115 284 ILE A CA  
1956 C C   . ILE A 285 ? 0.47934 0.52085 0.45118 0.06782  -0.00125 -0.04138 284 ILE A C   
1957 O O   . ILE A 285 ? 0.47724 0.50318 0.44002 0.07408  -0.00273 -0.03893 284 ILE A O   
1958 C CB  . ILE A 285 ? 0.49897 0.58216 0.50131 0.04839  -0.00238 -0.04056 284 ILE A CB  
1959 C CG1 . ILE A 285 ? 0.40444 0.51879 0.42240 0.04435  -0.00210 -0.04068 284 ILE A CG1 
1960 C CG2 . ILE A 285 ? 0.41515 0.48009 0.41341 0.04339  -0.00528 -0.03795 284 ILE A CG2 
1961 C CD1 . ILE A 285 ? 0.41815 0.53413 0.44475 0.02900  -0.00226 -0.04063 284 ILE A CD1 
1962 N N   . GLN A 286 ? 0.49386 0.52068 0.45771 0.06214  -0.00027 -0.04413 285 GLN A N   
1963 C CA  . GLN A 286 ? 0.50651 0.49820 0.45106 0.06052  -0.00159 -0.04496 285 GLN A CA  
1964 C C   . GLN A 286 ? 0.49306 0.46522 0.41848 0.07709  0.00152  -0.04694 285 GLN A C   
1965 O O   . GLN A 286 ? 0.56906 0.50812 0.47600 0.07685  0.00047  -0.04709 285 GLN A O   
1966 C CB  . GLN A 286 ? 0.47664 0.46083 0.41770 0.04819  -0.00254 -0.04721 285 GLN A CB  
1967 C CG  . GLN A 286 ? 0.49489 0.49302 0.45281 0.03337  -0.00539 -0.04393 285 GLN A CG  
1968 C CD  . GLN A 286 ? 0.49536 0.48537 0.44915 0.02164  -0.00765 -0.04428 285 GLN A CD  
1969 O OE1 . GLN A 286 ? 0.47306 0.47112 0.42595 0.02123  -0.00595 -0.04638 285 GLN A OE1 
1970 N NE2 . GLN A 286 ? 0.49169 0.46771 0.44306 0.01170  -0.01161 -0.04156 285 GLN A NE2 
1971 N N   . ASN A 287 ? 0.49454 0.48594 0.42353 0.09153  0.00577  -0.04810 286 ASN A N   
1972 C CA  . ASN A 287 ? 0.50407 0.47975 0.41648 0.11129  0.00981  -0.04887 286 ASN A CA  
1973 C C   . ASN A 287 ? 0.56743 0.55124 0.48435 0.12326  0.00848  -0.04333 286 ASN A C   
1974 O O   . ASN A 287 ? 0.56291 0.53385 0.46649 0.14204  0.01183  -0.04235 286 ASN A O   
1975 C CB  . ASN A 287 ? 0.52393 0.51884 0.43793 0.12323  0.01616  -0.05214 286 ASN A CB  
1976 C CG  . ASN A 287 ? 0.61404 0.59016 0.51304 0.11656  0.01864  -0.05809 286 ASN A CG  
1977 O OD1 . ASN A 287 ? 0.62389 0.56381 0.50344 0.10913  0.01645  -0.06059 286 ASN A OD1 
1978 N ND2 . ASN A 287 ? 0.58281 0.58432 0.48999 0.11810  0.02306  -0.06015 286 ASN A ND2 
1979 N N   . HIS A 288 ? 0.53538 0.53932 0.46911 0.11370  0.00395  -0.03956 287 HIS A N   
1980 C CA  . HIS A 288 ? 0.52632 0.54034 0.46346 0.12382  0.00183  -0.03405 287 HIS A CA  
1981 C C   . HIS A 288 ? 0.55847 0.53200 0.47378 0.12872  0.00112  -0.03114 287 HIS A C   
1982 O O   . HIS A 288 ? 0.57247 0.51787 0.47781 0.11523  -0.00023 -0.03241 287 HIS A O   
1983 C CB  . HIS A 288 ? 0.50390 0.54386 0.45995 0.11004  -0.00263 -0.03188 287 HIS A CB  
1984 C CG  . HIS A 288 ? 0.50736 0.56612 0.46846 0.11933  -0.00548 -0.02666 287 HIS A CG  
1985 N ND1 . HIS A 288 ? 0.46717 0.50541 0.41670 0.12208  -0.00796 -0.02189 287 HIS A ND1 
1986 C CD2 . HIS A 288 ? 0.46172 0.55950 0.43779 0.12545  -0.00670 -0.02499 287 HIS A CD2 
1987 C CE1 . HIS A 288 ? 0.50718 0.57044 0.46338 0.13048  -0.01083 -0.01746 287 HIS A CE1 
1988 N NE2 . HIS A 288 ? 0.48880 0.58938 0.46161 0.13230  -0.01053 -0.01937 287 HIS A NE2 
1989 N N   . PRO A 289 ? 0.57033 0.54068 0.47775 0.14759  0.00198  -0.02648 288 PRO A N   
1990 C CA  . PRO A 289 ? 0.63804 0.56625 0.52221 0.15257  0.00189  -0.02278 288 PRO A CA  
1991 C C   . PRO A 289 ? 0.59730 0.51276 0.48135 0.13396  -0.00242 -0.02002 288 PRO A C   
1992 O O   . PRO A 289 ? 0.62396 0.49995 0.48871 0.12837  -0.00203 -0.01944 288 PRO A O   
1993 C CB  . PRO A 289 ? 0.61396 0.55499 0.49719 0.17552  0.00228  -0.01606 288 PRO A CB  
1994 C CG  . PRO A 289 ? 0.64097 0.61973 0.53963 0.18699  0.00524  -0.01849 288 PRO A CG  
1995 C CD  . PRO A 289 ? 0.58824 0.59326 0.50678 0.16607  0.00345  -0.02376 288 PRO A CD  
1996 N N   . TRP A 290 ? 0.51528 0.46232 0.41934 0.12353  -0.00598 -0.01847 289 TRP A N   
1997 C CA  . TRP A 290 ? 0.56159 0.49831 0.46562 0.10755  -0.00869 -0.01563 289 TRP A CA  
1998 C C   . TRP A 290 ? 0.57119 0.49149 0.47443 0.08917  -0.00847 -0.01957 289 TRP A C   
1999 O O   . TRP A 290 ? 0.59126 0.49519 0.48998 0.07722  -0.00961 -0.01664 289 TRP A O   
2000 C CB  . TRP A 290 ? 0.51823 0.49097 0.44149 0.10156  -0.01163 -0.01408 289 TRP A CB  
2001 C CG  . TRP A 290 ? 0.54793 0.51125 0.47035 0.08746  -0.01298 -0.01103 289 TRP A CG  
2002 C CD1 . TRP A 290 ? 0.52821 0.47595 0.43833 0.09023  -0.01379 -0.00459 289 TRP A CD1 
2003 C CD2 . TRP A 290 ? 0.50535 0.47453 0.43926 0.06947  -0.01282 -0.01355 289 TRP A CD2 
2004 N NE1 . TRP A 290 ? 0.53986 0.48483 0.45358 0.07452  -0.01366 -0.00336 289 TRP A NE1 
2005 C CE2 . TRP A 290 ? 0.54352 0.50190 0.47232 0.06242  -0.01299 -0.00874 289 TRP A CE2 
2006 C CE3 . TRP A 290 ? 0.49837 0.48094 0.44592 0.05962  -0.01210 -0.01863 289 TRP A CE3 
2007 C CZ2 . TRP A 290 ? 0.51579 0.47807 0.45390 0.04703  -0.01194 -0.00910 289 TRP A CZ2 
2008 C CZ3 . TRP A 290 ? 0.45005 0.43477 0.40618 0.04481  -0.01166 -0.01852 289 TRP A CZ3 
2009 C CH2 . TRP A 290 ? 0.49526 0.47074 0.44727 0.03919  -0.01134 -0.01392 289 TRP A CH2 
2010 N N   . MET A 291 ? 0.54753 0.47350 0.45494 0.08667  -0.00704 -0.02541 290 MET A N   
2011 C CA  . MET A 291 ? 0.56888 0.48574 0.47765 0.06934  -0.00789 -0.02848 290 MET A CA  
2012 C C   . MET A 291 ? 0.60980 0.48786 0.49540 0.06754  -0.00711 -0.03086 290 MET A C   
2013 O O   . MET A 291 ? 0.63811 0.50939 0.52317 0.05312  -0.00865 -0.03347 290 MET A O   
2014 C CB  . MET A 291 ? 0.54645 0.49109 0.47143 0.06563  -0.00721 -0.03288 290 MET A CB  
2015 C CG  . MET A 291 ? 0.53309 0.51158 0.47974 0.06119  -0.00824 -0.03136 290 MET A CG  
2016 S SD  . MET A 291 ? 0.58859 0.57429 0.54904 0.04125  -0.00954 -0.03137 290 MET A SD  
2017 C CE  . MET A 291 ? 0.46735 0.42710 0.41800 0.03288  -0.01118 -0.02669 290 MET A CE  
2018 N N   . GLN A 292 ? 0.63068 0.48239 0.49599 0.08154  -0.00490 -0.02987 291 GLN A N   
2019 C CA  . GLN A 292 ? 0.71787 0.52784 0.55695 0.08016  -0.00348 -0.03337 291 GLN A CA  
2020 C C   . GLN A 292 ? 0.75357 0.53449 0.58083 0.06477  -0.00601 -0.02951 291 GLN A C   
2021 O O   . GLN A 292 ? 0.68794 0.47590 0.52266 0.06173  -0.00735 -0.02300 291 GLN A O   
2022 C CB  . GLN A 292 ? 0.71906 0.50938 0.53906 0.10346  0.00127  -0.03399 291 GLN A CB  
2023 C CG  . GLN A 292 ? 0.71696 0.53947 0.54968 0.11892  0.00455  -0.03714 291 GLN A CG  
2024 C CD  . GLN A 292 ? 0.82570 0.66313 0.66695 0.10713  0.00442  -0.04371 291 GLN A CD  
2025 O OE1 . GLN A 292 ? 0.83354 0.64330 0.65585 0.10195  0.00562  -0.04930 291 GLN A OE1 
2026 N NE2 . GLN A 292 ? 0.68660 0.56632 0.55453 0.10214  0.00285  -0.04294 291 GLN A NE2 
2027 N N   . ASP A 293 ? 0.71513 0.46419 0.52318 0.05370  -0.00663 -0.03369 292 ASP A N   
2028 C CA  . ASP A 293 ? 0.80856 0.52802 0.60311 0.03645  -0.00904 -0.03045 292 ASP A CA  
2029 C C   . ASP A 293 ? 0.71380 0.46197 0.53266 0.01837  -0.01279 -0.02557 292 ASP A C   
2030 O O   . ASP A 293 ? 0.78500 0.52541 0.60288 0.01068  -0.01328 -0.01907 292 ASP A O   
2031 C CB  . ASP A 293 ? 0.87000 0.55712 0.64420 0.04705  -0.00635 -0.02497 292 ASP A CB  
2032 C CG  . ASP A 293 ? 0.95971 0.61638 0.70886 0.06783  -0.00153 -0.02897 292 ASP A CG  
2033 O OD1 . ASP A 293 ? 1.03169 0.66832 0.76506 0.06515  -0.00049 -0.03690 292 ASP A OD1 
2034 O OD2 . ASP A 293 ? 1.07260 0.72617 0.81730 0.08767  0.00139  -0.02399 292 ASP A OD2 
2035 N N   . VAL A 294 ? 0.65923 0.43998 0.49915 0.01216  -0.01471 -0.02825 293 VAL A N   
2036 C CA  . VAL A 294 ? 0.63447 0.44269 0.49758 -0.00249 -0.01724 -0.02364 293 VAL A CA  
2037 C C   . VAL A 294 ? 0.70350 0.49392 0.55864 -0.02326 -0.02057 -0.02145 293 VAL A C   
2038 O O   . VAL A 294 ? 0.71005 0.47524 0.54607 -0.03038 -0.02256 -0.02602 293 VAL A O   
2039 C CB  . VAL A 294 ? 0.63483 0.47780 0.51949 -0.00290 -0.01804 -0.02663 293 VAL A CB  
2040 C CG1 . VAL A 294 ? 0.65336 0.48654 0.52770 -0.00934 -0.02025 -0.03253 293 VAL A CG1 
2041 C CG2 . VAL A 294 ? 0.55661 0.42701 0.46490 -0.01426 -0.01928 -0.02141 293 VAL A CG2 
2042 N N   . LEU A 295 ? 0.62529 0.42930 0.49426 -0.03366 -0.02099 -0.01447 294 LEU A N   
2043 C CA  . LEU A 295 ? 0.66420 0.46069 0.53122 -0.05496 -0.02423 -0.01096 294 LEU A CA  
2044 C C   . LEU A 295 ? 0.64093 0.46136 0.52306 -0.06624 -0.02850 -0.01278 294 LEU A C   
2045 O O   . LEU A 295 ? 0.60726 0.45700 0.50856 -0.05922 -0.02790 -0.01381 294 LEU A O   
2046 C CB  . LEU A 295 ? 0.62285 0.43197 0.50249 -0.06142 -0.02218 -0.00219 294 LEU A CB  
2047 C CG  . LEU A 295 ? 0.62006 0.40597 0.48439 -0.05498 -0.01852 0.00247  294 LEU A CG  
2048 C CD1 . LEU A 295 ? 0.70299 0.50989 0.58366 -0.06240 -0.01599 0.01087  294 LEU A CD1 
2049 C CD2 . LEU A 295 ? 0.71190 0.45277 0.54642 -0.06326 -0.01954 0.00208  294 LEU A CD2 
2050 N N   . LEU A 296 ? 0.65185 0.45923 0.52425 -0.08470 -0.03314 -0.01263 295 LEU A N   
2051 C CA  . LEU A 296 ? 0.65669 0.48973 0.54433 -0.09758 -0.03832 -0.01189 295 LEU A CA  
2052 C C   . LEU A 296 ? 0.65027 0.51970 0.56751 -0.10266 -0.03730 -0.00300 295 LEU A C   
2053 O O   . LEU A 296 ? 0.61095 0.47956 0.53178 -0.10247 -0.03344 0.00247  295 LEU A O   
2054 C CB  . LEU A 296 ? 0.68291 0.49347 0.55118 -0.11788 -0.04444 -0.01369 295 LEU A CB  
2055 C CG  . LEU A 296 ? 0.78618 0.55337 0.61959 -0.11469 -0.04472 -0.02315 295 LEU A CG  
2056 C CD1 . LEU A 296 ? 0.80616 0.55321 0.62047 -0.13854 -0.05167 -0.02533 295 LEU A CD1 
2057 C CD2 . LEU A 296 ? 0.75889 0.53392 0.59208 -0.09826 -0.04320 -0.03031 295 LEU A CD2 
2058 N N   . PRO A 297 ? 0.61599 0.51713 0.55369 -0.10602 -0.04005 -0.00103 296 PRO A N   
2059 C CA  . PRO A 297 ? 0.59128 0.52619 0.55657 -0.10901 -0.03797 0.00771  296 PRO A CA  
2060 C C   . PRO A 297 ? 0.65929 0.59442 0.62628 -0.12605 -0.03904 0.01510  296 PRO A C   
2061 O O   . PRO A 297 ? 0.60459 0.55202 0.58408 -0.12397 -0.03359 0.02129  296 PRO A O   
2062 C CB  . PRO A 297 ? 0.60278 0.56506 0.58394 -0.11087 -0.04203 0.00869  296 PRO A CB  
2063 C CG  . PRO A 297 ? 0.60599 0.55274 0.57144 -0.10184 -0.04327 -0.00032 296 PRO A CG  
2064 C CD  . PRO A 297 ? 0.63800 0.54578 0.57428 -0.10446 -0.04399 -0.00619 296 PRO A CD  
2065 N N   . GLN A 298 ? 0.61885 0.54045 0.57226 -0.14392 -0.04573 0.01447  297 GLN A N   
2066 C CA  . GLN A 298 ? 0.65486 0.57696 0.60922 -0.16315 -0.04708 0.02179  297 GLN A CA  
2067 C C   . GLN A 298 ? 0.69476 0.58789 0.63334 -0.16028 -0.04107 0.02281  297 GLN A C   
2068 O O   . GLN A 298 ? 0.67773 0.58257 0.62681 -0.16747 -0.03745 0.03115  297 GLN A O   
2069 C CB  . GLN A 298 ? 0.71010 0.61865 0.64826 -0.18452 -0.05620 0.01937  297 GLN A CB  
2070 N N   . GLU A 299 ? 0.67669 0.53260 0.58966 -0.14910 -0.03956 0.01514  298 GLU A N   
2071 C CA  . GLU A 299 ? 0.71805 0.54639 0.61527 -0.14296 -0.03387 0.01699  298 GLU A CA  
2072 C C   . GLU A 299 ? 0.68365 0.53702 0.60072 -0.12836 -0.02705 0.02182  298 GLU A C   
2073 O O   . GLU A 299 ? 0.69745 0.54505 0.61199 -0.13018 -0.02248 0.02809  298 GLU A O   
2074 C CB  . GLU A 299 ? 0.72360 0.51130 0.59165 -0.12967 -0.03325 0.00834  298 GLU A CB  
2075 C CG  . GLU A 299 ? 0.78084 0.53387 0.62172 -0.14326 -0.03853 0.00230  298 GLU A CG  
2076 C CD  . GLU A 299 ? 0.86429 0.58042 0.67803 -0.12585 -0.03634 -0.00666 298 GLU A CD  
2077 O OE1 . GLU A 299 ? 0.77519 0.50385 0.59753 -0.10387 -0.03247 -0.00871 298 GLU A OE1 
2078 O OE2 . GLU A 299 ? 0.98270 0.65749 0.76608 -0.13429 -0.03819 -0.01162 298 GLU A OE2 
2079 N N   . THR A 300 ? 0.63441 0.51388 0.56919 -0.11451 -0.02609 0.01882  299 THR A N   
2080 C CA  . THR A 300 ? 0.64241 0.54380 0.59368 -0.10158 -0.01977 0.02195  299 THR A CA  
2081 C C   . THR A 300 ? 0.67982 0.60763 0.65081 -0.11212 -0.01663 0.03122  299 THR A C   
2082 O O   . THR A 300 ? 0.63735 0.56768 0.60996 -0.10805 -0.01053 0.03577  299 THR A O   
2083 C CB  . THR A 300 ? 0.61332 0.53553 0.57844 -0.08798 -0.01966 0.01673  299 THR A CB  
2084 O OG1 . THR A 300 ? 0.55857 0.45934 0.50632 -0.07830 -0.02185 0.00864  299 THR A OG1 
2085 C CG2 . THR A 300 ? 0.51804 0.45781 0.49571 -0.07560 -0.01324 0.01847  299 THR A CG2 
2086 N N   . ALA A 301 ? 0.60824 0.55762 0.59416 -0.12531 -0.02059 0.03458  300 ALA A N   
2087 C CA  . ALA A 301 ? 0.66656 0.64592 0.67386 -0.13444 -0.01717 0.04430  300 ALA A CA  
2088 C C   . ALA A 301 ? 0.73568 0.69937 0.73145 -0.14876 -0.01525 0.05055  300 ALA A C   
2089 O O   . ALA A 301 ? 0.69894 0.67714 0.70457 -0.14845 -0.00814 0.05759  300 ALA A O   
2090 C CB  . ALA A 301 ? 0.66312 0.67091 0.68878 -0.14510 -0.02301 0.04746  300 ALA A CB  
2091 N N   . GLU A 302 ? 0.70713 0.63897 0.67996 -0.16160 -0.02085 0.04798  301 GLU A N   
2092 C CA  . GLU A 302 ? 0.77288 0.68681 0.73292 -0.17823 -0.01931 0.05447  301 GLU A CA  
2093 C C   . GLU A 302 ? 0.75233 0.64245 0.69658 -0.16618 -0.01210 0.05569  301 GLU A C   
2094 O O   . GLU A 302 ? 0.72388 0.61527 0.66804 -0.17462 -0.00693 0.06411  301 GLU A O   
2095 C CB  . GLU A 302 ? 0.75891 0.63939 0.69460 -0.19558 -0.02709 0.05037  301 GLU A CB  
2096 C CG  . GLU A 302 ? 0.79936 0.70498 0.74884 -0.21311 -0.03528 0.05116  301 GLU A CG  
2097 C CD  . GLU A 302 ? 0.95629 0.82497 0.87723 -0.23120 -0.04316 0.04545  301 GLU A CD  
2098 O OE1 . GLU A 302 ? 0.99578 0.81709 0.88591 -0.22499 -0.04173 0.03912  301 GLU A OE1 
2099 O OE2 . GLU A 302 ? 0.90671 0.79346 0.83506 -0.25138 -0.05077 0.04739  301 GLU A OE2 
2100 N N   . ILE A 303 ? 0.73646 0.60699 0.66748 -0.14657 -0.01167 0.04813  302 ILE A N   
2101 C CA  . ILE A 303 ? 0.70394 0.55165 0.61797 -0.13457 -0.00628 0.04973  302 ILE A CA  
2102 C C   . ILE A 303 ? 0.70365 0.58143 0.63591 -0.12183 0.00049  0.05284  302 ILE A C   
2103 O O   . ILE A 303 ? 0.71121 0.58434 0.63716 -0.12097 0.00623  0.05912  302 ILE A O   
2104 C CB  . ILE A 303 ? 0.72005 0.53520 0.61150 -0.11894 -0.00893 0.04122  302 ILE A CB  
2105 C CG1 . ILE A 303 ? 0.75512 0.53201 0.62192 -0.13156 -0.01390 0.03808  302 ILE A CG1 
2106 C CG2 . ILE A 303 ? 0.74221 0.54107 0.61944 -0.10329 -0.00404 0.04374  302 ILE A CG2 
2107 C CD1 . ILE A 303 ? 0.79633 0.54102 0.64044 -0.11473 -0.01531 0.02971  302 ILE A CD1 
2108 N N   . HIS A 304 ? 0.66343 0.57038 0.61635 -0.11229 0.00028  0.04852  303 HIS A N   
2109 C CA  . HIS A 304 ? 0.68145 0.60991 0.64637 -0.09828 0.00653  0.04876  303 HIS A CA  
2110 C C   . HIS A 304 ? 0.66113 0.62752 0.65316 -0.10191 0.01095  0.05321  303 HIS A C   
2111 O O   . HIS A 304 ? 0.67118 0.65185 0.66984 -0.09301 0.01798  0.05463  303 HIS A O   
2112 C CB  . HIS A 304 ? 0.63031 0.55768 0.59369 -0.08085 0.00425  0.03955  303 HIS A CB  
2113 C CG  . HIS A 304 ? 0.64630 0.54169 0.58517 -0.07192 0.00161  0.03585  303 HIS A CG  
2114 N ND1 . HIS A 304 ? 0.65624 0.54119 0.58216 -0.06204 0.00491  0.03808  303 HIS A ND1 
2115 C CD2 . HIS A 304 ? 0.63466 0.50672 0.55898 -0.07006 -0.00362 0.03050  303 HIS A CD2 
2116 C CE1 . HIS A 304 ? 0.65400 0.51187 0.56000 -0.05357 0.00168  0.03507  303 HIS A CE1 
2117 N NE2 . HIS A 304 ? 0.71237 0.56104 0.61671 -0.05787 -0.00291 0.03009  303 HIS A NE2 
2118 N N   . LEU A 305 ? 0.67304 0.65616 0.67986 -0.11391 0.00726  0.05560  304 LEU A N   
2119 C CA  . LEU A 305 ? 0.70211 0.72321 0.73616 -0.11398 0.01139  0.06031  304 LEU A CA  
2120 C C   . LEU A 305 ? 0.75944 0.79967 0.80576 -0.13124 0.01336  0.07089  304 LEU A C   
2121 O O   . LEU A 305 ? 0.81638 0.88682 0.88263 -0.12846 0.02068  0.07693  304 LEU A O   
2122 C CB  . LEU A 305 ? 0.62780 0.66275 0.67458 -0.11038 0.00563  0.05566  304 LEU A CB  
2123 C CG  . LEU A 305 ? 0.63139 0.65171 0.66861 -0.09509 0.00356  0.04557  304 LEU A CG  
2124 C CD1 . LEU A 305 ? 0.51773 0.55314 0.56774 -0.09287 -0.00122 0.04258  304 LEU A CD1 
2125 C CD2 . LEU A 305 ? 0.56618 0.58954 0.60358 -0.08050 0.01137  0.04353  304 LEU A CD2 
2126 N N   . HIS A 306 ? 0.78228 0.80609 0.81694 -0.14912 0.00754  0.07334  305 HIS A N   
2127 C CA  . HIS A 306 ? 0.84704 0.89151 0.89404 -0.16856 0.00869  0.08386  305 HIS A CA  
2128 C C   . HIS A 306 ? 0.86928 0.90667 0.90800 -0.17176 0.01762  0.09082  305 HIS A C   
2129 O O   . HIS A 306 ? 0.99835 1.06373 1.05378 -0.16639 0.02686  0.09687  305 HIS A O   
2130 C CB  . HIS A 306 ? 0.90732 0.93580 0.94316 -0.18966 -0.00160 0.08336  305 HIS A CB  
2131 C CG  . HIS A 306 ? 0.88251 0.92546 0.92882 -0.19033 -0.01043 0.07888  305 HIS A CG  
2132 N ND1 . HIS A 306 ? 0.92332 0.94975 0.95638 -0.20723 -0.02068 0.07571  305 HIS A ND1 
2133 C CD2 . HIS A 306 ? 0.79665 0.86719 0.86321 -0.17646 -0.01039 0.07724  305 HIS A CD2 
2134 C CE1 . HIS A 306 ? 0.85205 0.89759 0.89723 -0.20357 -0.02688 0.07256  305 HIS A CE1 
2135 N NE2 . HIS A 306 ? 0.77315 0.84534 0.83911 -0.18478 -0.02073 0.07392  305 HIS A NE2 
2136 N N   . ARG B 2   ? 1.06068 1.10970 0.80792 -0.00839 0.05113  -0.02920 2   ARG B N   
2137 C CA  . ARG B 2   ? 1.08973 1.12884 0.85220 -0.01164 0.05197  -0.02987 2   ARG B CA  
2138 C C   . ARG B 2   ? 1.06485 1.07452 0.83473 0.00056  0.06452  -0.03736 2   ARG B C   
2139 O O   . ARG B 2   ? 1.08174 1.08520 0.85626 0.01722  0.07011  -0.03183 2   ARG B O   
2140 C CB  . ARG B 2   ? 1.05955 1.11864 0.84122 -0.00732 0.04357  -0.01005 2   ARG B CB  
2141 C CG  . ARG B 2   ? 1.00020 1.05501 0.79621 -0.01461 0.04174  -0.00983 2   ARG B CG  
2142 C CD  . ARG B 2   ? 0.93169 1.00952 0.74487 -0.01188 0.03232  0.01014  2   ARG B CD  
2143 N NE  . ARG B 2   ? 0.89144 0.99730 0.69558 -0.02269 0.02095  0.01664  2   ARG B NE  
2144 C CZ  . ARG B 2   ? 0.85539 0.97982 0.65692 -0.01518 0.01637  0.02877  2   ARG B CZ  
2145 N NH1 . ARG B 2   ? 0.77730 0.89600 0.58462 0.00320  0.02184  0.03622  2   ARG B NH1 
2146 N NH2 . ARG B 2   ? 0.74889 0.89820 0.54169 -0.02642 0.00601  0.03354  2   ARG B NH2 
2147 N N   . LYS B 3   ? 0.97925 0.97081 0.75030 -0.00778 0.06883  -0.04982 3   LYS B N   
2148 C CA  . LYS B 3   ? 0.92443 0.88641 0.69943 0.00158  0.08120  -0.05987 3   LYS B CA  
2149 C C   . LYS B 3   ? 0.85105 0.80823 0.64979 0.01589  0.08335  -0.04711 3   LYS B C   
2150 O O   . LYS B 3   ? 0.87430 0.83518 0.68609 0.01059  0.07919  -0.04214 3   LYS B O   
2151 C CB  . LYS B 3   ? 0.93722 0.88148 0.70379 -0.01301 0.08500  -0.07819 3   LYS B CB  
2152 C CG  . LYS B 3   ? 0.93921 0.85225 0.70610 -0.00449 0.09829  -0.09083 3   LYS B CG  
2153 N N   . ARG B 4   ? 0.76042 0.70909 0.56467 0.03401  0.08992  -0.04192 4   ARG B N   
2154 C CA  . ARG B 4   ? 0.73770 0.67738 0.56309 0.04930  0.09389  -0.03173 4   ARG B CA  
2155 C C   . ARG B 4   ? 0.69004 0.59844 0.51675 0.05383  0.10605  -0.04585 4   ARG B C   
2156 O O   . ARG B 4   ? 0.72081 0.61490 0.53389 0.05567  0.11348  -0.05823 4   ARG B O   
2157 C CB  . ARG B 4   ? 0.71502 0.66389 0.54586 0.06675  0.09364  -0.01721 4   ARG B CB  
2158 C CG  . ARG B 4   ? 0.60559 0.54097 0.45561 0.08479  0.09980  -0.00878 4   ARG B CG  
2159 C CD  . ARG B 4   ? 0.59556 0.54202 0.44915 0.10064  0.09848  0.00566  4   ARG B CD  
2160 N NE  . ARG B 4   ? 0.58903 0.51920 0.45782 0.11899  0.10596  0.01132  4   ARG B NE  
2161 C CZ  . ARG B 4   ? 0.57432 0.50718 0.46252 0.12672  0.10382  0.02448  4   ARG B CZ  
2162 N NH1 . ARG B 4   ? 0.57139 0.52233 0.46706 0.11787  0.09463  0.03350  4   ARG B NH1 
2163 N NH2 . ARG B 4   ? 0.54824 0.46529 0.44863 0.14382  0.11108  0.02878  4   ARG B NH2 
2164 N N   . ARG B 5   ? 0.65826 0.55609 0.50120 0.05557  0.10816  -0.04402 5   ARG B N   
2165 C CA  . ARG B 5   ? 0.68674 0.55508 0.53119 0.05824  0.11924  -0.05779 5   ARG B CA  
2166 C C   . ARG B 5   ? 0.66409 0.52259 0.53093 0.07178  0.12287  -0.04812 5   ARG B C   
2167 O O   . ARG B 5   ? 0.65074 0.52514 0.53212 0.07447  0.11585  -0.03256 5   ARG B O   
2168 C CB  . ARG B 5   ? 0.75442 0.61520 0.58995 0.03916  0.11881  -0.07300 5   ARG B CB  
2169 C CG  . ARG B 5   ? 0.78403 0.65390 0.63330 0.03017  0.11179  -0.06620 5   ARG B CG  
2170 C CD  . ARG B 5   ? 0.87091 0.73236 0.70998 0.01108  0.11162  -0.08215 5   ARG B CD  
2171 N NE  . ARG B 5   ? 0.91842 0.77699 0.77322 0.00610  0.10967  -0.07910 5   ARG B NE  
2172 C CZ  . ARG B 5   ? 0.92865 0.76379 0.79387 0.01206  0.11823  -0.08440 5   ARG B CZ  
2173 N NH1 . ARG B 5   ? 0.92698 0.73923 0.78912 0.02347  0.12940  -0.09291 5   ARG B NH1 
2174 N NH2 . ARG B 5   ? 0.92903 0.76376 0.80818 0.00645  0.11555  -0.08101 5   ARG B NH2 
2175 N N   . ARG B 6   ? 0.68298 0.51481 0.55223 0.08052  0.13413  -0.05757 6   ARG B N   
2176 C CA  . ARG B 6   ? 0.69200 0.50992 0.58104 0.09146  0.13893  -0.05205 6   ARG B CA  
2177 C C   . ARG B 6   ? 0.70816 0.52189 0.60330 0.07800  0.13688  -0.05706 6   ARG B C   
2178 O O   . ARG B 6   ? 0.67087 0.48558 0.55315 0.06097  0.13449  -0.06876 6   ARG B O   
2179 C CB  . ARG B 6   ? 0.72654 0.51679 0.61505 0.10438  0.15178  -0.06161 6   ARG B CB  
2180 C CG  . ARG B 6   ? 0.69180 0.48414 0.57710 0.11978  0.15461  -0.05568 6   ARG B CG  
2181 C CD  . ARG B 6   ? 0.72009 0.48456 0.60381 0.13106  0.16744  -0.06663 6   ARG B CD  
2182 N NE  . ARG B 6   ? 0.66745 0.43368 0.55065 0.14698  0.17009  -0.05950 6   ARG B NE  
2183 C CZ  . ARG B 6   ? 0.67704 0.44248 0.57659 0.16318  0.17090  -0.04635 6   ARG B CZ  
2184 N NH1 . ARG B 6   ? 0.64738 0.41330 0.56627 0.16400  0.16729  -0.03814 6   ARG B NH1 
2185 N NH2 . ARG B 6   ? 0.65191 0.43297 0.55490 0.16584  0.16285  -0.03803 6   ARG B NH2 
2186 N N   . HIS B 7   ? 0.63354 0.44236 0.54849 0.08582  0.13786  -0.04803 7   HIS B N   
2187 C CA  . HIS B 7   ? 0.70872 0.51247 0.63210 0.07488  0.13649  -0.05146 7   HIS B CA  
2188 C C   . HIS B 7   ? 0.72924 0.50744 0.66637 0.08668  0.14652  -0.05402 7   HIS B C   
2189 O O   . HIS B 7   ? 0.70715 0.48685 0.66111 0.10136  0.14691  -0.04005 7   HIS B O   
2190 C CB  . HIS B 7   ? 0.62212 0.45130 0.55748 0.07001  0.12501  -0.03519 7   HIS B CB  
2191 C CG  . HIS B 7   ? 0.64659 0.50216 0.56959 0.05922  0.11471  -0.03119 7   HIS B CG  
2192 N ND1 . HIS B 7   ? 0.61042 0.48196 0.53013 0.06839  0.11117  -0.02049 7   HIS B ND1 
2193 C CD2 . HIS B 7   ? 0.64629 0.51500 0.55933 0.04004  0.10714  -0.03643 7   HIS B CD2 
2194 C CE1 . HIS B 7   ? 0.63802 0.53146 0.54628 0.05543  0.10198  -0.01928 7   HIS B CE1 
2195 N NE2 . HIS B 7   ? 0.64568 0.53797 0.54970 0.03812  0.09929  -0.02882 7   HIS B NE2 
2196 N N   . PRO B 8   ? 0.77625 0.53079 0.70683 0.08113  0.15473  -0.07120 8   PRO B N   
2197 C CA  . PRO B 8   ? 0.82070 0.55014 0.76399 0.09246  0.16463  -0.07413 8   PRO B CA  
2198 C C   . PRO B 8   ? 0.86359 0.59736 0.82754 0.09356  0.16092  -0.06248 8   PRO B C   
2199 O O   . PRO B 8   ? 0.82629 0.57690 0.79268 0.08053  0.15202  -0.05794 8   PRO B O   
2200 C CB  . PRO B 8   ? 0.88465 0.59201 0.81482 0.08144  0.17193  -0.09528 8   PRO B CB  
2201 C CG  . PRO B 8   ? 0.88077 0.59833 0.78920 0.07053  0.16853  -0.10359 8   PRO B CG  
2202 C CD  . PRO B 8   ? 0.85079 0.59967 0.76101 0.06507  0.15580  -0.08900 8   PRO B CD  
2203 N N   . SER B 9   ? 0.89040 0.60872 0.86936 0.10952  0.16791  -0.05752 9   SER B N   
2204 C CA  . SER B 9   ? 0.84294 0.56331 0.84250 0.11303  0.16556  -0.04596 9   SER B CA  
2205 C C   . SER B 9   ? 0.94852 0.65124 0.95063 0.10230  0.16970  -0.05808 9   SER B C   
2206 O O   . SER B 9   ? 1.04998 0.72955 1.04355 0.10128  0.17879  -0.07398 9   SER B O   
2207 C CB  . SER B 9   ? 0.83680 0.54758 0.85114 0.13495  0.17136  -0.03547 9   SER B CB  
2208 O OG  . SER B 9   ? 0.79949 0.52523 0.81092 0.14524  0.16799  -0.02477 9   SER B OG  
2209 N N   . GLY B 10  ? 0.91790 0.63168 0.93189 0.09434  0.16303  -0.05035 10  GLY B N   
2210 C CA  . GLY B 10  ? 0.94765 0.64674 0.96547 0.08358  0.16593  -0.06026 10  GLY B CA  
2211 C C   . GLY B 10  ? 1.00410 0.71067 1.00725 0.06136  0.16036  -0.07150 10  GLY B C   
2212 O O   . GLY B 10  ? 0.99596 0.72753 0.99689 0.05154  0.14970  -0.06380 10  GLY B O   
# 
