data_8R0W
# 
_entry.id   8R0W 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R0W         pdb_00008r0w 10.2210/pdb8r0w/pdb 
WWPDB D_1292134412 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R0W 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'complexed with another inhibitor' 7QB2 unspecified 
PDB 'complexed with another inhibitor' 7QFM unspecified 
PDB 'complexed with another inhibitor' 7Z6U unspecified 
PDB 'complexed with another inhibitor' 8AFR unspecified 
PDB 'complexed with another inhibitor' 8R0H unspecified 
PDB 'complexed with another inhibitor' 8R0Q unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wibke.diederich@staff.uni-marburg.de 
_pdbx_contact_author.name_first         Wibke 
_pdbx_contact_author.name_last          Diederich 
_pdbx_contact_author.name_mi            E. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5671-6575 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hochban, P.M.M.' 1 0000-0003-3526-7314 
'Heine, A.'       2 0000-0002-5285-4089 
'Diederich, W.E.' 3 0000-0001-5671-6575 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Pim1 in complex with 5-bromobenzo[d]oxazol-2-amine and Pimtide' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hochban, P.M.M.' 1 0000-0003-3526-7314 
primary 'Daude, M.'       2 ?                   
primary 'Heine, A.'       3 0000-0002-5285-4089 
primary 'Diederich, W.E.' 4 0000-0001-5671-6575 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Serine/threonine-protein kinase pim-1' 35670.477 1   2.7.11.1 R250G ? ? 
2 polymer     syn Pimtide                                 1592.850  1   ?        ?     ? ? 
3 non-polymer syn 1,2-ETHANEDIOL                          62.068    1   ?        ?     ? ? 
4 non-polymer syn GLYCEROL                                92.094    3   ?        ?     ? ? 
5 non-polymer syn '5-bromobenzo[d]oxazol-2-amine'         213.031   1   ?        ?     ? ? 
6 water       nat water                                   18.015    173 ?        ?     ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;SMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGE
LPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
IPFEHDEEIIGGQVFFRQRVS(SEP)ECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
;SMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGE
LPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
IPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
A ? 
2 'polypeptide(L)' no no  ARKRRRHPSGPPTA ARKRRRHPSGPPTA B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 1,2-ETHANEDIOL                  EDO 
4 GLYCEROL                        GOL 
5 '5-bromobenzo[d]oxazol-2-amine' XGF 
6 water                           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   MET n 
1 3   LEU n 
1 4   LEU n 
1 5   SER n 
1 6   LYS n 
1 7   ILE n 
1 8   ASN n 
1 9   SER n 
1 10  LEU n 
1 11  ALA n 
1 12  HIS n 
1 13  LEU n 
1 14  ARG n 
1 15  ALA n 
1 16  ALA n 
1 17  PRO n 
1 18  CYS n 
1 19  ASN n 
1 20  ASP n 
1 21  LEU n 
1 22  HIS n 
1 23  ALA n 
1 24  THR n 
1 25  LYS n 
1 26  LEU n 
1 27  ALA n 
1 28  PRO n 
1 29  GLY n 
1 30  LYS n 
1 31  GLU n 
1 32  LYS n 
1 33  GLU n 
1 34  PRO n 
1 35  LEU n 
1 36  GLU n 
1 37  SER n 
1 38  GLN n 
1 39  TYR n 
1 40  GLN n 
1 41  VAL n 
1 42  GLY n 
1 43  PRO n 
1 44  LEU n 
1 45  LEU n 
1 46  GLY n 
1 47  SER n 
1 48  GLY n 
1 49  GLY n 
1 50  PHE n 
1 51  GLY n 
1 52  SER n 
1 53  VAL n 
1 54  TYR n 
1 55  SER n 
1 56  GLY n 
1 57  ILE n 
1 58  ARG n 
1 59  VAL n 
1 60  SER n 
1 61  ASP n 
1 62  ASN n 
1 63  LEU n 
1 64  PRO n 
1 65  VAL n 
1 66  ALA n 
1 67  ILE n 
1 68  LYS n 
1 69  HIS n 
1 70  VAL n 
1 71  GLU n 
1 72  LYS n 
1 73  ASP n 
1 74  ARG n 
1 75  ILE n 
1 76  SER n 
1 77  ASP n 
1 78  TRP n 
1 79  GLY n 
1 80  GLU n 
1 81  LEU n 
1 82  PRO n 
1 83  ASN n 
1 84  GLY n 
1 85  THR n 
1 86  ARG n 
1 87  VAL n 
1 88  PRO n 
1 89  MET n 
1 90  GLU n 
1 91  VAL n 
1 92  VAL n 
1 93  LEU n 
1 94  LEU n 
1 95  LYS n 
1 96  LYS n 
1 97  VAL n 
1 98  SER n 
1 99  SER n 
1 100 GLY n 
1 101 PHE n 
1 102 SER n 
1 103 GLY n 
1 104 VAL n 
1 105 ILE n 
1 106 ARG n 
1 107 LEU n 
1 108 LEU n 
1 109 ASP n 
1 110 TRP n 
1 111 PHE n 
1 112 GLU n 
1 113 ARG n 
1 114 PRO n 
1 115 ASP n 
1 116 SER n 
1 117 PHE n 
1 118 VAL n 
1 119 LEU n 
1 120 ILE n 
1 121 LEU n 
1 122 GLU n 
1 123 ARG n 
1 124 PRO n 
1 125 GLU n 
1 126 PRO n 
1 127 VAL n 
1 128 GLN n 
1 129 ASP n 
1 130 LEU n 
1 131 PHE n 
1 132 ASP n 
1 133 PHE n 
1 134 ILE n 
1 135 THR n 
1 136 GLU n 
1 137 ARG n 
1 138 GLY n 
1 139 ALA n 
1 140 LEU n 
1 141 GLN n 
1 142 GLU n 
1 143 GLU n 
1 144 LEU n 
1 145 ALA n 
1 146 ARG n 
1 147 SER n 
1 148 PHE n 
1 149 PHE n 
1 150 TRP n 
1 151 GLN n 
1 152 VAL n 
1 153 LEU n 
1 154 GLU n 
1 155 ALA n 
1 156 VAL n 
1 157 ARG n 
1 158 HIS n 
1 159 CYS n 
1 160 HIS n 
1 161 ASN n 
1 162 CYS n 
1 163 GLY n 
1 164 VAL n 
1 165 LEU n 
1 166 HIS n 
1 167 ARG n 
1 168 ASP n 
1 169 ILE n 
1 170 LYS n 
1 171 ASP n 
1 172 GLU n 
1 173 ASN n 
1 174 ILE n 
1 175 LEU n 
1 176 ILE n 
1 177 ASP n 
1 178 LEU n 
1 179 ASN n 
1 180 ARG n 
1 181 GLY n 
1 182 GLU n 
1 183 LEU n 
1 184 LYS n 
1 185 LEU n 
1 186 ILE n 
1 187 ASP n 
1 188 PHE n 
1 189 GLY n 
1 190 SER n 
1 191 GLY n 
1 192 ALA n 
1 193 LEU n 
1 194 LEU n 
1 195 LYS n 
1 196 ASP n 
1 197 THR n 
1 198 VAL n 
1 199 TYR n 
1 200 THR n 
1 201 ASP n 
1 202 PHE n 
1 203 ASP n 
1 204 GLY n 
1 205 THR n 
1 206 ARG n 
1 207 VAL n 
1 208 TYR n 
1 209 SER n 
1 210 PRO n 
1 211 PRO n 
1 212 GLU n 
1 213 TRP n 
1 214 ILE n 
1 215 ARG n 
1 216 TYR n 
1 217 HIS n 
1 218 ARG n 
1 219 TYR n 
1 220 HIS n 
1 221 GLY n 
1 222 ARG n 
1 223 SER n 
1 224 ALA n 
1 225 ALA n 
1 226 VAL n 
1 227 TRP n 
1 228 SER n 
1 229 LEU n 
1 230 GLY n 
1 231 ILE n 
1 232 LEU n 
1 233 LEU n 
1 234 TYR n 
1 235 ASP n 
1 236 MET n 
1 237 VAL n 
1 238 CYS n 
1 239 GLY n 
1 240 ASP n 
1 241 ILE n 
1 242 PRO n 
1 243 PHE n 
1 244 GLU n 
1 245 HIS n 
1 246 ASP n 
1 247 GLU n 
1 248 GLU n 
1 249 ILE n 
1 250 ILE n 
1 251 GLY n 
1 252 GLY n 
1 253 GLN n 
1 254 VAL n 
1 255 PHE n 
1 256 PHE n 
1 257 ARG n 
1 258 GLN n 
1 259 ARG n 
1 260 VAL n 
1 261 SER n 
1 262 SEP n 
1 263 GLU n 
1 264 CYS n 
1 265 GLN n 
1 266 HIS n 
1 267 LEU n 
1 268 ILE n 
1 269 ARG n 
1 270 TRP n 
1 271 CYS n 
1 272 LEU n 
1 273 ALA n 
1 274 LEU n 
1 275 ARG n 
1 276 PRO n 
1 277 SER n 
1 278 ASP n 
1 279 ARG n 
1 280 PRO n 
1 281 THR n 
1 282 PHE n 
1 283 GLU n 
1 284 GLU n 
1 285 ILE n 
1 286 GLN n 
1 287 ASN n 
1 288 HIS n 
1 289 PRO n 
1 290 TRP n 
1 291 MET n 
1 292 GLN n 
1 293 ASP n 
1 294 VAL n 
1 295 LEU n 
1 296 LEU n 
1 297 PRO n 
1 298 GLN n 
1 299 GLU n 
1 300 THR n 
1 301 ALA n 
1 302 GLU n 
1 303 ILE n 
1 304 HIS n 
1 305 LEU n 
1 306 HIS n 
1 307 SER n 
1 308 LEU n 
1 309 SER n 
1 310 PRO n 
1 311 GLY n 
1 312 PRO n 
1 313 SER n 
2 1   ALA n 
2 2   ARG n 
2 3   LYS n 
2 4   ARG n 
2 5   ARG n 
2 6   ARG n 
2 7   HIS n 
2 8   PRO n 
2 9   SER n 
2 10  GLY n 
2 11  PRO n 
2 12  PRO n 
2 13  THR n 
2 14  ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   313 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PIM1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pLIC-SGC 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       14 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   human 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                         ?                                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                        ?                                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                      ?                                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                 ?                                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                        ?                                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL                  'ETHYLENE GLYCOL'                 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE                       ?                                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                 ?                                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                         ?                                 'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                        'GLYCERIN; PROPANE-1,2,3-TRIOL'   'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                       ?                                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                           ?                                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                      ?                                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                         ?                                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                          ?                                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                      ?                                 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                   ?                                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                         ?                                 'C5 H9 N O2'     115.130 
SEP 'L-peptide linking' n PHOSPHOSERINE                   PHOSPHONOSERINE                   'C3 H8 N O6 P'   185.072 
SER 'L-peptide linking' y SERINE                          ?                                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                       ?                                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                      ?                                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                        ?                                 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                          ?                                 'C5 H11 N O2'    117.146 
XGF non-polymer         . '5-bromobenzo[d]oxazol-2-amine' 5-bromanyl-1,3-benzoxazol-2-amine 'C7 H5 Br N2 O'  213.031 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   0   ?   ?   ?   A . n 
A 1 2   MET 2   1   ?   ?   ?   A . n 
A 1 3   LEU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   SER 5   4   ?   ?   ?   A . n 
A 1 6   LYS 6   5   ?   ?   ?   A . n 
A 1 7   ILE 7   6   ?   ?   ?   A . n 
A 1 8   ASN 8   7   ?   ?   ?   A . n 
A 1 9   SER 9   8   ?   ?   ?   A . n 
A 1 10  LEU 10  9   ?   ?   ?   A . n 
A 1 11  ALA 11  10  ?   ?   ?   A . n 
A 1 12  HIS 12  11  ?   ?   ?   A . n 
A 1 13  LEU 13  12  ?   ?   ?   A . n 
A 1 14  ARG 14  13  ?   ?   ?   A . n 
A 1 15  ALA 15  14  ?   ?   ?   A . n 
A 1 16  ALA 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  CYS 18  17  ?   ?   ?   A . n 
A 1 19  ASN 19  18  ?   ?   ?   A . n 
A 1 20  ASP 20  19  ?   ?   ?   A . n 
A 1 21  LEU 21  20  ?   ?   ?   A . n 
A 1 22  HIS 22  21  ?   ?   ?   A . n 
A 1 23  ALA 23  22  ?   ?   ?   A . n 
A 1 24  THR 24  23  ?   ?   ?   A . n 
A 1 25  LYS 25  24  ?   ?   ?   A . n 
A 1 26  LEU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  PRO 28  27  ?   ?   ?   A . n 
A 1 29  GLY 29  28  ?   ?   ?   A . n 
A 1 30  LYS 30  29  ?   ?   ?   A . n 
A 1 31  GLU 31  30  ?   ?   ?   A . n 
A 1 32  LYS 32  31  ?   ?   ?   A . n 
A 1 33  GLU 33  32  ?   ?   ?   A . n 
A 1 34  PRO 34  33  33  PRO PRO A . n 
A 1 35  LEU 35  34  34  LEU LEU A . n 
A 1 36  GLU 36  35  35  GLU GLU A . n 
A 1 37  SER 37  36  36  SER SER A . n 
A 1 38  GLN 38  37  37  GLN GLN A . n 
A 1 39  TYR 39  38  38  TYR TYR A . n 
A 1 40  GLN 40  39  39  GLN GLN A . n 
A 1 41  VAL 41  40  40  VAL VAL A . n 
A 1 42  GLY 42  41  41  GLY GLY A . n 
A 1 43  PRO 43  42  42  PRO PRO A . n 
A 1 44  LEU 44  43  43  LEU LEU A . n 
A 1 45  LEU 45  44  44  LEU LEU A . n 
A 1 46  GLY 46  45  45  GLY GLY A . n 
A 1 47  SER 47  46  46  SER SER A . n 
A 1 48  GLY 48  47  47  GLY GLY A . n 
A 1 49  GLY 49  48  48  GLY GLY A . n 
A 1 50  PHE 50  49  49  PHE PHE A . n 
A 1 51  GLY 51  50  50  GLY GLY A . n 
A 1 52  SER 52  51  51  SER SER A . n 
A 1 53  VAL 53  52  52  VAL VAL A . n 
A 1 54  TYR 54  53  53  TYR TYR A . n 
A 1 55  SER 55  54  54  SER SER A . n 
A 1 56  GLY 56  55  55  GLY GLY A . n 
A 1 57  ILE 57  56  56  ILE ILE A . n 
A 1 58  ARG 58  57  57  ARG ARG A . n 
A 1 59  VAL 59  58  58  VAL VAL A . n 
A 1 60  SER 60  59  59  SER SER A . n 
A 1 61  ASP 61  60  60  ASP ASP A . n 
A 1 62  ASN 62  61  61  ASN ASN A . n 
A 1 63  LEU 63  62  62  LEU LEU A . n 
A 1 64  PRO 64  63  63  PRO PRO A . n 
A 1 65  VAL 65  64  64  VAL VAL A . n 
A 1 66  ALA 66  65  65  ALA ALA A . n 
A 1 67  ILE 67  66  66  ILE ILE A . n 
A 1 68  LYS 68  67  67  LYS LYS A . n 
A 1 69  HIS 69  68  68  HIS HIS A . n 
A 1 70  VAL 70  69  69  VAL VAL A . n 
A 1 71  GLU 71  70  70  GLU GLU A . n 
A 1 72  LYS 72  71  71  LYS LYS A . n 
A 1 73  ASP 73  72  72  ASP ASP A . n 
A 1 74  ARG 74  73  73  ARG ARG A . n 
A 1 75  ILE 75  74  74  ILE ILE A . n 
A 1 76  SER 76  75  75  SER SER A . n 
A 1 77  ASP 77  76  76  ASP ASP A . n 
A 1 78  TRP 78  77  77  TRP TRP A . n 
A 1 79  GLY 79  78  78  GLY GLY A . n 
A 1 80  GLU 80  79  79  GLU GLU A . n 
A 1 81  LEU 81  80  80  LEU LEU A . n 
A 1 82  PRO 82  81  81  PRO PRO A . n 
A 1 83  ASN 83  82  82  ASN ASN A . n 
A 1 84  GLY 84  83  83  GLY GLY A . n 
A 1 85  THR 85  84  84  THR THR A . n 
A 1 86  ARG 86  85  85  ARG ARG A . n 
A 1 87  VAL 87  86  86  VAL VAL A . n 
A 1 88  PRO 88  87  87  PRO PRO A . n 
A 1 89  MET 89  88  88  MET MET A . n 
A 1 90  GLU 90  89  89  GLU GLU A . n 
A 1 91  VAL 91  90  90  VAL VAL A . n 
A 1 92  VAL 92  91  91  VAL VAL A . n 
A 1 93  LEU 93  92  92  LEU LEU A . n 
A 1 94  LEU 94  93  93  LEU LEU A . n 
A 1 95  LYS 95  94  94  LYS LYS A . n 
A 1 96  LYS 96  95  95  LYS LYS A . n 
A 1 97  VAL 97  96  96  VAL VAL A . n 
A 1 98  SER 98  97  97  SER SER A . n 
A 1 99  SER 99  98  98  SER SER A . n 
A 1 100 GLY 100 99  99  GLY GLY A . n 
A 1 101 PHE 101 100 100 PHE PHE A . n 
A 1 102 SER 102 101 101 SER SER A . n 
A 1 103 GLY 103 102 102 GLY GLY A . n 
A 1 104 VAL 104 103 103 VAL VAL A . n 
A 1 105 ILE 105 104 104 ILE ILE A . n 
A 1 106 ARG 106 105 105 ARG ARG A . n 
A 1 107 LEU 107 106 106 LEU LEU A . n 
A 1 108 LEU 108 107 107 LEU LEU A . n 
A 1 109 ASP 109 108 108 ASP ASP A . n 
A 1 110 TRP 110 109 109 TRP TRP A . n 
A 1 111 PHE 111 110 110 PHE PHE A . n 
A 1 112 GLU 112 111 111 GLU GLU A . n 
A 1 113 ARG 113 112 112 ARG ARG A . n 
A 1 114 PRO 114 113 113 PRO PRO A . n 
A 1 115 ASP 115 114 114 ASP ASP A . n 
A 1 116 SER 116 115 115 SER SER A . n 
A 1 117 PHE 117 116 116 PHE PHE A . n 
A 1 118 VAL 118 117 117 VAL VAL A . n 
A 1 119 LEU 119 118 118 LEU LEU A . n 
A 1 120 ILE 120 119 119 ILE ILE A . n 
A 1 121 LEU 121 120 120 LEU LEU A . n 
A 1 122 GLU 122 121 121 GLU GLU A . n 
A 1 123 ARG 123 122 122 ARG ARG A . n 
A 1 124 PRO 124 123 123 PRO PRO A . n 
A 1 125 GLU 125 124 124 GLU GLU A . n 
A 1 126 PRO 126 125 125 PRO PRO A . n 
A 1 127 VAL 127 126 126 VAL VAL A . n 
A 1 128 GLN 128 127 127 GLN GLN A . n 
A 1 129 ASP 129 128 128 ASP ASP A . n 
A 1 130 LEU 130 129 129 LEU LEU A . n 
A 1 131 PHE 131 130 130 PHE PHE A . n 
A 1 132 ASP 132 131 131 ASP ASP A . n 
A 1 133 PHE 133 132 132 PHE PHE A . n 
A 1 134 ILE 134 133 133 ILE ILE A . n 
A 1 135 THR 135 134 134 THR THR A . n 
A 1 136 GLU 136 135 135 GLU GLU A . n 
A 1 137 ARG 137 136 136 ARG ARG A . n 
A 1 138 GLY 138 137 137 GLY GLY A . n 
A 1 139 ALA 139 138 138 ALA ALA A . n 
A 1 140 LEU 140 139 139 LEU LEU A . n 
A 1 141 GLN 141 140 140 GLN GLN A . n 
A 1 142 GLU 142 141 141 GLU GLU A . n 
A 1 143 GLU 143 142 142 GLU GLU A . n 
A 1 144 LEU 144 143 143 LEU LEU A . n 
A 1 145 ALA 145 144 144 ALA ALA A . n 
A 1 146 ARG 146 145 145 ARG ARG A . n 
A 1 147 SER 147 146 146 SER SER A . n 
A 1 148 PHE 148 147 147 PHE PHE A . n 
A 1 149 PHE 149 148 148 PHE PHE A . n 
A 1 150 TRP 150 149 149 TRP TRP A . n 
A 1 151 GLN 151 150 150 GLN GLN A . n 
A 1 152 VAL 152 151 151 VAL VAL A . n 
A 1 153 LEU 153 152 152 LEU LEU A . n 
A 1 154 GLU 154 153 153 GLU GLU A . n 
A 1 155 ALA 155 154 154 ALA ALA A . n 
A 1 156 VAL 156 155 155 VAL VAL A . n 
A 1 157 ARG 157 156 156 ARG ARG A . n 
A 1 158 HIS 158 157 157 HIS HIS A . n 
A 1 159 CYS 159 158 158 CYS CYS A . n 
A 1 160 HIS 160 159 159 HIS HIS A . n 
A 1 161 ASN 161 160 160 ASN ASN A . n 
A 1 162 CYS 162 161 161 CYS CYS A . n 
A 1 163 GLY 163 162 162 GLY GLY A . n 
A 1 164 VAL 164 163 163 VAL VAL A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 HIS 166 165 165 HIS HIS A . n 
A 1 167 ARG 167 166 166 ARG ARG A . n 
A 1 168 ASP 168 167 167 ASP ASP A . n 
A 1 169 ILE 169 168 168 ILE ILE A . n 
A 1 170 LYS 170 169 169 LYS LYS A . n 
A 1 171 ASP 171 170 170 ASP ASP A . n 
A 1 172 GLU 172 171 171 GLU GLU A . n 
A 1 173 ASN 173 172 172 ASN ASN A . n 
A 1 174 ILE 174 173 173 ILE ILE A . n 
A 1 175 LEU 175 174 174 LEU LEU A . n 
A 1 176 ILE 176 175 175 ILE ILE A . n 
A 1 177 ASP 177 176 176 ASP ASP A . n 
A 1 178 LEU 178 177 177 LEU LEU A . n 
A 1 179 ASN 179 178 178 ASN ASN A . n 
A 1 180 ARG 180 179 179 ARG ARG A . n 
A 1 181 GLY 181 180 180 GLY GLY A . n 
A 1 182 GLU 182 181 181 GLU GLU A . n 
A 1 183 LEU 183 182 182 LEU LEU A . n 
A 1 184 LYS 184 183 183 LYS LYS A . n 
A 1 185 LEU 185 184 184 LEU LEU A . n 
A 1 186 ILE 186 185 185 ILE ILE A . n 
A 1 187 ASP 187 186 186 ASP ASP A . n 
A 1 188 PHE 188 187 187 PHE PHE A . n 
A 1 189 GLY 189 188 188 GLY GLY A . n 
A 1 190 SER 190 189 189 SER SER A . n 
A 1 191 GLY 191 190 190 GLY GLY A . n 
A 1 192 ALA 192 191 191 ALA ALA A . n 
A 1 193 LEU 193 192 192 LEU LEU A . n 
A 1 194 LEU 194 193 193 LEU LEU A . n 
A 1 195 LYS 195 194 194 LYS LYS A . n 
A 1 196 ASP 196 195 195 ASP ASP A . n 
A 1 197 THR 197 196 196 THR THR A . n 
A 1 198 VAL 198 197 197 VAL VAL A . n 
A 1 199 TYR 199 198 198 TYR TYR A . n 
A 1 200 THR 200 199 199 THR THR A . n 
A 1 201 ASP 201 200 200 ASP ASP A . n 
A 1 202 PHE 202 201 201 PHE PHE A . n 
A 1 203 ASP 203 202 202 ASP ASP A . n 
A 1 204 GLY 204 203 203 GLY GLY A . n 
A 1 205 THR 205 204 204 THR THR A . n 
A 1 206 ARG 206 205 205 ARG ARG A . n 
A 1 207 VAL 207 206 206 VAL VAL A . n 
A 1 208 TYR 208 207 207 TYR TYR A . n 
A 1 209 SER 209 208 208 SER SER A . n 
A 1 210 PRO 210 209 209 PRO PRO A . n 
A 1 211 PRO 211 210 210 PRO PRO A . n 
A 1 212 GLU 212 211 211 GLU GLU A . n 
A 1 213 TRP 213 212 212 TRP TRP A . n 
A 1 214 ILE 214 213 213 ILE ILE A . n 
A 1 215 ARG 215 214 214 ARG ARG A . n 
A 1 216 TYR 216 215 215 TYR TYR A . n 
A 1 217 HIS 217 216 216 HIS HIS A . n 
A 1 218 ARG 218 217 217 ARG ARG A . n 
A 1 219 TYR 219 218 218 TYR TYR A . n 
A 1 220 HIS 220 219 219 HIS HIS A . n 
A 1 221 GLY 221 220 220 GLY GLY A . n 
A 1 222 ARG 222 221 221 ARG ARG A . n 
A 1 223 SER 223 222 222 SER SER A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 ALA 225 224 224 ALA ALA A . n 
A 1 226 VAL 226 225 225 VAL VAL A . n 
A 1 227 TRP 227 226 226 TRP TRP A . n 
A 1 228 SER 228 227 227 SER SER A . n 
A 1 229 LEU 229 228 228 LEU LEU A . n 
A 1 230 GLY 230 229 229 GLY GLY A . n 
A 1 231 ILE 231 230 230 ILE ILE A . n 
A 1 232 LEU 232 231 231 LEU LEU A . n 
A 1 233 LEU 233 232 232 LEU LEU A . n 
A 1 234 TYR 234 233 233 TYR TYR A . n 
A 1 235 ASP 235 234 234 ASP ASP A . n 
A 1 236 MET 236 235 235 MET MET A . n 
A 1 237 VAL 237 236 236 VAL VAL A . n 
A 1 238 CYS 238 237 237 CYS CYS A . n 
A 1 239 GLY 239 238 238 GLY GLY A . n 
A 1 240 ASP 240 239 239 ASP ASP A . n 
A 1 241 ILE 241 240 240 ILE ILE A . n 
A 1 242 PRO 242 241 241 PRO PRO A . n 
A 1 243 PHE 243 242 242 PHE PHE A . n 
A 1 244 GLU 244 243 243 GLU GLU A . n 
A 1 245 HIS 245 244 244 HIS HIS A . n 
A 1 246 ASP 246 245 245 ASP ASP A . n 
A 1 247 GLU 247 246 246 GLU GLU A . n 
A 1 248 GLU 248 247 247 GLU GLU A . n 
A 1 249 ILE 249 248 248 ILE ILE A . n 
A 1 250 ILE 250 249 249 ILE ILE A . n 
A 1 251 GLY 251 250 250 GLY GLY A . n 
A 1 252 GLY 252 251 251 GLY GLY A . n 
A 1 253 GLN 253 252 252 GLN GLN A . n 
A 1 254 VAL 254 253 253 VAL VAL A . n 
A 1 255 PHE 255 254 254 PHE PHE A . n 
A 1 256 PHE 256 255 255 PHE PHE A . n 
A 1 257 ARG 257 256 256 ARG ARG A . n 
A 1 258 GLN 258 257 257 GLN GLN A . n 
A 1 259 ARG 259 258 258 ARG ARG A . n 
A 1 260 VAL 260 259 259 VAL VAL A . n 
A 1 261 SER 261 260 260 SER SER A . n 
A 1 262 SEP 262 261 261 SEP SEP A . n 
A 1 263 GLU 263 262 262 GLU GLU A . n 
A 1 264 CYS 264 263 263 CYS CYS A . n 
A 1 265 GLN 265 264 264 GLN GLN A . n 
A 1 266 HIS 266 265 265 HIS HIS A . n 
A 1 267 LEU 267 266 266 LEU LEU A . n 
A 1 268 ILE 268 267 267 ILE ILE A . n 
A 1 269 ARG 269 268 268 ARG ARG A . n 
A 1 270 TRP 270 269 269 TRP TRP A . n 
A 1 271 CYS 271 270 270 CYS CYS A . n 
A 1 272 LEU 272 271 271 LEU LEU A . n 
A 1 273 ALA 273 272 272 ALA ALA A . n 
A 1 274 LEU 274 273 273 LEU LEU A . n 
A 1 275 ARG 275 274 274 ARG ARG A . n 
A 1 276 PRO 276 275 275 PRO PRO A . n 
A 1 277 SER 277 276 276 SER SER A . n 
A 1 278 ASP 278 277 277 ASP ASP A . n 
A 1 279 ARG 279 278 278 ARG ARG A . n 
A 1 280 PRO 280 279 279 PRO PRO A . n 
A 1 281 THR 281 280 280 THR THR A . n 
A 1 282 PHE 282 281 281 PHE PHE A . n 
A 1 283 GLU 283 282 282 GLU GLU A . n 
A 1 284 GLU 284 283 283 GLU GLU A . n 
A 1 285 ILE 285 284 284 ILE ILE A . n 
A 1 286 GLN 286 285 285 GLN GLN A . n 
A 1 287 ASN 287 286 286 ASN ASN A . n 
A 1 288 HIS 288 287 287 HIS HIS A . n 
A 1 289 PRO 289 288 288 PRO PRO A . n 
A 1 290 TRP 290 289 289 TRP TRP A . n 
A 1 291 MET 291 290 290 MET MET A . n 
A 1 292 GLN 292 291 291 GLN GLN A . n 
A 1 293 ASP 293 292 292 ASP ASP A . n 
A 1 294 VAL 294 293 293 VAL VAL A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 LEU 296 295 295 LEU LEU A . n 
A 1 297 PRO 297 296 296 PRO PRO A . n 
A 1 298 GLN 298 297 297 GLN GLN A . n 
A 1 299 GLU 299 298 298 GLU GLU A . n 
A 1 300 THR 300 299 299 THR THR A . n 
A 1 301 ALA 301 300 300 ALA ALA A . n 
A 1 302 GLU 302 301 301 GLU GLU A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 HIS 304 303 303 HIS HIS A . n 
A 1 305 LEU 305 304 304 LEU LEU A . n 
A 1 306 HIS 306 305 305 HIS HIS A . n 
A 1 307 SER 307 306 ?   ?   ?   A . n 
A 1 308 LEU 308 307 ?   ?   ?   A . n 
A 1 309 SER 309 308 ?   ?   ?   A . n 
A 1 310 PRO 310 309 ?   ?   ?   A . n 
A 1 311 GLY 311 310 ?   ?   ?   A . n 
A 1 312 PRO 312 311 ?   ?   ?   A . n 
A 1 313 SER 313 312 ?   ?   ?   A . n 
B 2 1   ALA 1   1   ?   ?   ?   B . n 
B 2 2   ARG 2   2   2   ARG ARG B . n 
B 2 3   LYS 3   3   3   LYS LYS B . n 
B 2 4   ARG 4   4   4   ARG ARG B . n 
B 2 5   ARG 5   5   5   ARG ARG B . n 
B 2 6   ARG 6   6   6   ARG ARG B . n 
B 2 7   HIS 7   7   7   HIS HIS B . n 
B 2 8   PRO 8   8   8   PRO PRO B . n 
B 2 9   SER 9   9   9   SER SER B . n 
B 2 10  GLY 10  10  ?   ?   ?   B . n 
B 2 11  PRO 11  11  ?   ?   ?   B . n 
B 2 12  PRO 12  12  ?   ?   ?   B . n 
B 2 13  THR 13  13  ?   ?   ?   B . n 
B 2 14  ALA 14  14  ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XGF 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XGF 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 EDO 1   401 1   EDO EDO A . 
D 4 GOL 1   402 1   GOL GOL A . 
E 4 GOL 1   403 2   GOL GOL A . 
F 4 GOL 1   404 3   GOL GOL A . 
G 5 XGF 1   405 1   XGF dp5 A . 
H 6 HOH 1   501 187 HOH HOH A . 
H 6 HOH 2   502 41  HOH HOH A . 
H 6 HOH 3   503 90  HOH HOH A . 
H 6 HOH 4   504 21  HOH HOH A . 
H 6 HOH 5   505 179 HOH HOH A . 
H 6 HOH 6   506 153 HOH HOH A . 
H 6 HOH 7   507 48  HOH HOH A . 
H 6 HOH 8   508 88  HOH HOH A . 
H 6 HOH 9   509 86  HOH HOH A . 
H 6 HOH 10  510 78  HOH HOH A . 
H 6 HOH 11  511 82  HOH HOH A . 
H 6 HOH 12  512 166 HOH HOH A . 
H 6 HOH 13  513 137 HOH HOH A . 
H 6 HOH 14  514 133 HOH HOH A . 
H 6 HOH 15  515 117 HOH HOH A . 
H 6 HOH 16  516 105 HOH HOH A . 
H 6 HOH 17  517 155 HOH HOH A . 
H 6 HOH 18  518 60  HOH HOH A . 
H 6 HOH 19  519 134 HOH HOH A . 
H 6 HOH 20  520 3   HOH HOH A . 
H 6 HOH 21  521 67  HOH HOH A . 
H 6 HOH 22  522 39  HOH HOH A . 
H 6 HOH 23  523 30  HOH HOH A . 
H 6 HOH 24  524 6   HOH HOH A . 
H 6 HOH 25  525 122 HOH HOH A . 
H 6 HOH 26  526 17  HOH HOH A . 
H 6 HOH 27  527 74  HOH HOH A . 
H 6 HOH 28  528 42  HOH HOH A . 
H 6 HOH 29  529 38  HOH HOH A . 
H 6 HOH 30  530 149 HOH HOH A . 
H 6 HOH 31  531 99  HOH HOH A . 
H 6 HOH 32  532 91  HOH HOH A . 
H 6 HOH 33  533 80  HOH HOH A . 
H 6 HOH 34  534 125 HOH HOH A . 
H 6 HOH 35  535 4   HOH HOH A . 
H 6 HOH 36  536 44  HOH HOH A . 
H 6 HOH 37  537 22  HOH HOH A . 
H 6 HOH 38  538 20  HOH HOH A . 
H 6 HOH 39  539 156 HOH HOH A . 
H 6 HOH 40  540 142 HOH HOH A . 
H 6 HOH 41  541 46  HOH HOH A . 
H 6 HOH 42  542 131 HOH HOH A . 
H 6 HOH 43  543 108 HOH HOH A . 
H 6 HOH 44  544 31  HOH HOH A . 
H 6 HOH 45  545 52  HOH HOH A . 
H 6 HOH 46  546 53  HOH HOH A . 
H 6 HOH 47  547 61  HOH HOH A . 
H 6 HOH 48  548 71  HOH HOH A . 
H 6 HOH 49  549 55  HOH HOH A . 
H 6 HOH 50  550 171 HOH HOH A . 
H 6 HOH 51  551 92  HOH HOH A . 
H 6 HOH 52  552 13  HOH HOH A . 
H 6 HOH 53  553 161 HOH HOH A . 
H 6 HOH 54  554 168 HOH HOH A . 
H 6 HOH 55  555 102 HOH HOH A . 
H 6 HOH 56  556 70  HOH HOH A . 
H 6 HOH 57  557 124 HOH HOH A . 
H 6 HOH 58  558 2   HOH HOH A . 
H 6 HOH 59  559 154 HOH HOH A . 
H 6 HOH 60  560 129 HOH HOH A . 
H 6 HOH 61  561 40  HOH HOH A . 
H 6 HOH 62  562 62  HOH HOH A . 
H 6 HOH 63  563 28  HOH HOH A . 
H 6 HOH 64  564 37  HOH HOH A . 
H 6 HOH 65  565 147 HOH HOH A . 
H 6 HOH 66  566 25  HOH HOH A . 
H 6 HOH 67  567 176 HOH HOH A . 
H 6 HOH 68  568 12  HOH HOH A . 
H 6 HOH 69  569 114 HOH HOH A . 
H 6 HOH 70  570 65  HOH HOH A . 
H 6 HOH 71  571 120 HOH HOH A . 
H 6 HOH 72  572 116 HOH HOH A . 
H 6 HOH 73  573 158 HOH HOH A . 
H 6 HOH 74  574 50  HOH HOH A . 
H 6 HOH 75  575 32  HOH HOH A . 
H 6 HOH 76  576 29  HOH HOH A . 
H 6 HOH 77  577 14  HOH HOH A . 
H 6 HOH 78  578 173 HOH HOH A . 
H 6 HOH 79  579 170 HOH HOH A . 
H 6 HOH 80  580 45  HOH HOH A . 
H 6 HOH 81  581 24  HOH HOH A . 
H 6 HOH 82  582 5   HOH HOH A . 
H 6 HOH 83  583 81  HOH HOH A . 
H 6 HOH 84  584 148 HOH HOH A . 
H 6 HOH 85  585 107 HOH HOH A . 
H 6 HOH 86  586 185 HOH HOH A . 
H 6 HOH 87  587 18  HOH HOH A . 
H 6 HOH 88  588 85  HOH HOH A . 
H 6 HOH 89  589 97  HOH HOH A . 
H 6 HOH 90  590 58  HOH HOH A . 
H 6 HOH 91  591 51  HOH HOH A . 
H 6 HOH 92  592 19  HOH HOH A . 
H 6 HOH 93  593 109 HOH HOH A . 
H 6 HOH 94  594 1   HOH HOH A . 
H 6 HOH 95  595 146 HOH HOH A . 
H 6 HOH 96  596 36  HOH HOH A . 
H 6 HOH 97  597 174 HOH HOH A . 
H 6 HOH 98  598 104 HOH HOH A . 
H 6 HOH 99  599 113 HOH HOH A . 
H 6 HOH 100 600 110 HOH HOH A . 
H 6 HOH 101 601 123 HOH HOH A . 
H 6 HOH 102 602 72  HOH HOH A . 
H 6 HOH 103 603 139 HOH HOH A . 
H 6 HOH 104 604 100 HOH HOH A . 
H 6 HOH 105 605 26  HOH HOH A . 
H 6 HOH 106 606 126 HOH HOH A . 
H 6 HOH 107 607 106 HOH HOH A . 
H 6 HOH 108 608 57  HOH HOH A . 
H 6 HOH 109 609 101 HOH HOH A . 
H 6 HOH 110 610 95  HOH HOH A . 
H 6 HOH 111 611 59  HOH HOH A . 
H 6 HOH 112 612 141 HOH HOH A . 
H 6 HOH 113 613 84  HOH HOH A . 
H 6 HOH 114 614 87  HOH HOH A . 
H 6 HOH 115 615 79  HOH HOH A . 
H 6 HOH 116 616 10  HOH HOH A . 
H 6 HOH 117 617 33  HOH HOH A . 
H 6 HOH 118 618 23  HOH HOH A . 
H 6 HOH 119 619 8   HOH HOH A . 
H 6 HOH 120 620 121 HOH HOH A . 
H 6 HOH 121 621 143 HOH HOH A . 
H 6 HOH 122 622 172 HOH HOH A . 
H 6 HOH 123 623 83  HOH HOH A . 
H 6 HOH 124 624 138 HOH HOH A . 
H 6 HOH 125 625 64  HOH HOH A . 
H 6 HOH 126 626 7   HOH HOH A . 
H 6 HOH 127 627 69  HOH HOH A . 
H 6 HOH 128 628 16  HOH HOH A . 
H 6 HOH 129 629 96  HOH HOH A . 
H 6 HOH 130 630 49  HOH HOH A . 
H 6 HOH 131 631 127 HOH HOH A . 
H 6 HOH 132 632 27  HOH HOH A . 
H 6 HOH 133 633 115 HOH HOH A . 
H 6 HOH 134 634 130 HOH HOH A . 
H 6 HOH 135 635 15  HOH HOH A . 
H 6 HOH 136 636 98  HOH HOH A . 
H 6 HOH 137 637 112 HOH HOH A . 
H 6 HOH 138 638 181 HOH HOH A . 
H 6 HOH 139 639 68  HOH HOH A . 
H 6 HOH 140 640 135 HOH HOH A . 
H 6 HOH 141 641 167 HOH HOH A . 
H 6 HOH 142 642 9   HOH HOH A . 
H 6 HOH 143 643 162 HOH HOH A . 
H 6 HOH 144 644 75  HOH HOH A . 
H 6 HOH 145 645 183 HOH HOH A . 
H 6 HOH 146 646 157 HOH HOH A . 
H 6 HOH 147 647 63  HOH HOH A . 
H 6 HOH 148 648 128 HOH HOH A . 
H 6 HOH 149 649 186 HOH HOH A . 
H 6 HOH 150 650 151 HOH HOH A . 
H 6 HOH 151 651 178 HOH HOH A . 
H 6 HOH 152 652 184 HOH HOH A . 
H 6 HOH 153 653 188 HOH HOH A . 
H 6 HOH 154 654 35  HOH HOH A . 
H 6 HOH 155 655 164 HOH HOH A . 
H 6 HOH 156 656 119 HOH HOH A . 
H 6 HOH 157 657 160 HOH HOH A . 
H 6 HOH 158 658 182 HOH HOH A . 
H 6 HOH 159 659 34  HOH HOH A . 
H 6 HOH 160 660 73  HOH HOH A . 
H 6 HOH 161 661 165 HOH HOH A . 
H 6 HOH 162 662 94  HOH HOH A . 
H 6 HOH 163 663 111 HOH HOH A . 
H 6 HOH 164 664 66  HOH HOH A . 
H 6 HOH 165 665 152 HOH HOH A . 
I 6 HOH 1   101 77  HOH HOH B . 
I 6 HOH 2   102 76  HOH HOH B . 
I 6 HOH 3   103 43  HOH HOH B . 
I 6 HOH 4   104 136 HOH HOH B . 
I 6 HOH 5   105 54  HOH HOH B . 
I 6 HOH 6   106 118 HOH HOH B . 
I 6 HOH 7   107 169 HOH HOH B . 
I 6 HOH 8   108 93  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LEU 34  ? CG  ? A LEU 35  CG  
2  1 Y 1 A LEU 34  ? CD1 ? A LEU 35  CD1 
3  1 Y 1 A LEU 34  ? CD2 ? A LEU 35  CD2 
4  1 Y 1 A GLU 35  ? CG  ? A GLU 36  CG  
5  1 Y 1 A GLU 35  ? CD  ? A GLU 36  CD  
6  1 Y 1 A GLU 35  ? OE1 ? A GLU 36  OE1 
7  1 Y 1 A GLU 35  ? OE2 ? A GLU 36  OE2 
8  1 Y 1 A SER 36  ? OG  ? A SER 37  OG  
9  1 Y 1 A GLN 39  ? CG  ? A GLN 40  CG  
10 1 Y 1 A GLN 39  ? CD  ? A GLN 40  CD  
11 1 Y 1 A GLN 39  ? OE1 ? A GLN 40  OE1 
12 1 Y 1 A GLN 39  ? NE2 ? A GLN 40  NE2 
13 1 Y 1 A ILE 56  ? CD1 ? A ILE 57  CD1 
14 1 Y 1 A VAL 58  ? CG1 ? A VAL 59  CG1 
15 1 Y 1 A ASN 61  ? OD1 ? A ASN 62  OD1 
16 1 Y 1 A ASN 61  ? ND2 ? A ASN 62  ND2 
17 1 Y 1 A SER 75  ? OG  ? A SER 76  OG  
18 1 Y 1 A ASP 76  ? OD1 ? A ASP 77  OD1 
19 1 Y 1 A ASP 76  ? OD2 ? A ASP 77  OD2 
20 1 Y 1 A GLU 79  ? CG  ? A GLU 80  CG  
21 1 Y 1 A GLU 79  ? CD  ? A GLU 80  CD  
22 1 Y 1 A GLU 79  ? OE1 ? A GLU 80  OE1 
23 1 Y 1 A GLU 79  ? OE2 ? A GLU 80  OE2 
24 1 Y 1 A LEU 80  ? CD1 ? A LEU 81  CD1 
25 1 Y 1 A LEU 80  ? CD2 ? A LEU 81  CD2 
26 1 Y 1 A ARG 85  ? CD  ? A ARG 86  CD  
27 1 Y 1 A ARG 85  ? NE  ? A ARG 86  NE  
28 1 Y 1 A ARG 85  ? CZ  ? A ARG 86  CZ  
29 1 Y 1 A ARG 85  ? NH1 ? A ARG 86  NH1 
30 1 Y 1 A ARG 85  ? NH2 ? A ARG 86  NH2 
31 1 Y 1 A LYS 94  ? CD  ? A LYS 95  CD  
32 1 Y 1 A LYS 94  ? CE  ? A LYS 95  CE  
33 1 Y 1 A LYS 94  ? NZ  ? A LYS 95  NZ  
34 1 Y 1 A SER 98  ? OG  ? A SER 99  OG  
35 1 Y 1 A ASN 178 ? ND2 ? A ASN 179 ND2 
36 1 Y 1 A ASP 202 ? OD1 ? A ASP 203 OD1 
37 1 Y 1 A ASP 202 ? OD2 ? A ASP 203 OD2 
38 1 Y 1 A ARG 214 ? NH1 ? A ARG 215 NH1 
39 1 Y 1 A GLU 246 ? OE1 ? A GLU 247 OE1 
40 1 Y 1 A GLN 252 ? OE1 ? A GLN 253 OE1 
41 1 Y 1 A GLN 252 ? NE2 ? A GLN 253 NE2 
42 1 Y 1 A GLU 262 ? OE1 ? A GLU 263 OE1 
43 1 Y 1 A ARG 274 ? CD  ? A ARG 275 CD  
44 1 Y 1 A ARG 274 ? NE  ? A ARG 275 NE  
45 1 Y 1 A ARG 274 ? CZ  ? A ARG 275 CZ  
46 1 Y 1 A ARG 274 ? NH1 ? A ARG 275 NH1 
47 1 Y 1 A ARG 274 ? NH2 ? A ARG 275 NH2 
48 1 Y 1 A GLN 297 ? CG  ? A GLN 298 CG  
49 1 Y 1 A GLN 297 ? CD  ? A GLN 298 CD  
50 1 Y 1 A GLN 297 ? OE1 ? A GLN 298 OE1 
51 1 Y 1 A GLN 297 ? NE2 ? A GLN 298 NE2 
52 1 Y 1 B LYS 3   ? CG  ? B LYS 3   CG  
53 1 Y 1 B LYS 3   ? CD  ? B LYS 3   CD  
54 1 Y 1 B LYS 3   ? CE  ? B LYS 3   CE  
55 1 Y 1 B LYS 3   ? NZ  ? B LYS 3   NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? MxCuBE ? ? ? 1.20.1_4487 2 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 3.1.9       3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 3.1.9       4 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           5 
? 'model building'  ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? 0.7.1       6 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R0W 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     96.241 
_cell.length_a_esd                 ? 
_cell.length_b                     96.241 
_cell.length_b_esd                 ? 
_cell.length_c                     79.837 
_cell.length_c_esd                 ? 
_cell.volume                       640405.562 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R0W 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                170 
_symmetry.space_group_name_Hall            'P 65' 
_symmetry.space_group_name_H-M             'P 65' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R0W 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.0 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          37.4 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'100 mM bis-tris-propane (pH 7.0), 10% ethylene glycol, 0.3% DMSO, 20% PEG3350, 200 mM Mg(OAc)2' 
_exptl_crystal_grow.pdbx_pH_range   6.8-7.2 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9763 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9763 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P14 (MX2)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          37.44 
_reflns.entry_id                                       8R0W 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.95 
_reflns.d_resolution_low                               48.12 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     30712 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          22.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                6.3 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.95 
_reflns_shell.d_res_low                                     1.96 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4918 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.84 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               42.74 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R0W 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.95 
_refine.ls_d_res_low                             41.67 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     30705 
_refine.ls_number_reflns_R_free                  1536 
_refine.ls_number_reflns_R_work                  29169 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.88 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1674 
_refine.ls_R_factor_R_free                       0.2012 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1656 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.3148 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2211 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.95 
_refine_hist.d_res_low                        41.67 
_refine_hist.number_atoms_solvent             173 
_refine_hist.number_atoms_total               2448 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2242 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         33 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0074  ? 2352 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.8023  ? 3187 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0558  ? 337  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0085  ? 414  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 12.4282 ? 862  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.95 2.01  . . 139 2633 99.25  . . . . 0.2379 . . . . . . . . . . . 0.3101 
'X-RAY DIFFRACTION' 2.01 2.08  . . 139 2654 99.89  . . . . 0.1963 . . . . . . . . . . . 0.2400 
'X-RAY DIFFRACTION' 2.08 2.17  . . 137 2602 99.93  . . . . 0.1810 . . . . . . . . . . . 0.1968 
'X-RAY DIFFRACTION' 2.17 2.27  . . 139 2637 99.75  . . . . 0.1752 . . . . . . . . . . . 0.2260 
'X-RAY DIFFRACTION' 2.27 2.39  . . 140 2646 99.96  . . . . 0.1606 . . . . . . . . . . . 0.1884 
'X-RAY DIFFRACTION' 2.39 2.53  . . 139 2656 100.00 . . . . 0.1661 . . . . . . . . . . . 0.1938 
'X-RAY DIFFRACTION' 2.53 2.73  . . 139 2644 100.00 . . . . 0.1766 . . . . . . . . . . . 0.1906 
'X-RAY DIFFRACTION' 2.73 3.00  . . 140 2655 100.00 . . . . 0.1746 . . . . . . . . . . . 0.2319 
'X-RAY DIFFRACTION' 3.01 3.44  . . 140 2666 100.00 . . . . 0.1696 . . . . . . . . . . . 0.2026 
'X-RAY DIFFRACTION' 3.44 4.33  . . 141 2669 100.00 . . . . 0.1498 . . . . . . . . . . . 0.1861 
'X-RAY DIFFRACTION' 4.33 41.67 . . 143 2707 99.93  . . . . 0.1591 . . . . . . . . . . . 0.1937 
# 
_struct.entry_id                     8R0W 
_struct.title                        'Pim1 in complex with 5-bromobenzo[d]oxazol-2-amine and Pimtide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R0W 
_struct_keywords.text            
;SERINE KINASE, KINASE, COMPLEX, PIM1, PIM, PIM-1, INHIBITOR, TUMORIGENISIS, CANCER, PIMTIDE, PROTO ONCOGEN, ATP, PHOSPHORYLATION, APOPTOSIS, CELL CYCLE, TRANSFERASE
;
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 5 ? 
H N N 6 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP PIM1_HUMAN P11309 P11309-1 1 
;MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL
PNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN
CGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPS
;
1 
2 PDB 8R0W       8R0W   ?        2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R0W A 2 ? 313 ? P11309 1 ? 312 ? 1 312 
2 2 8R0W B 1 ? 14  ? 8R0W   1 ? 14  ? 1 14  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R0W SER A 1   ? UNP P11309 ?   ?   'expression tag'      0   1 
1 8R0W GLY A 251 ? UNP P11309 ARG 250 'engineered mutation' 250 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2030  ? 
1 MORE         7     ? 
1 'SSA (A^2)'  12900 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 34  ? GLN A 38  ? PRO A 33  GLN A 37  1 ? 5  
HELX_P HELX_P2  AA2 GLY A 46  ? GLY A 49  ? GLY A 45  GLY A 48  5 ? 4  
HELX_P HELX_P3  AA3 ASP A 73  ? ILE A 75  ? ASP A 72  ILE A 74  5 ? 3  
HELX_P HELX_P4  AA4 MET A 89  ? SER A 98  ? MET A 88  SER A 97  1 ? 10 
HELX_P HELX_P5  AA5 LEU A 130 ? GLY A 138 ? LEU A 129 GLY A 137 1 ? 9  
HELX_P HELX_P6  AA6 GLN A 141 ? CYS A 162 ? GLN A 140 CYS A 161 1 ? 22 
HELX_P HELX_P7  AA7 LYS A 170 ? GLU A 172 ? LYS A 169 GLU A 171 5 ? 3  
HELX_P HELX_P8  AA8 THR A 205 ? SER A 209 ? THR A 204 SER A 208 5 ? 5  
HELX_P HELX_P9  AA9 PRO A 210 ? HIS A 217 ? PRO A 209 HIS A 216 1 ? 8  
HELX_P HELX_P10 AB1 HIS A 220 ? GLY A 239 ? HIS A 219 GLY A 238 1 ? 20 
HELX_P HELX_P11 AB2 HIS A 245 ? GLY A 252 ? HIS A 244 GLY A 251 1 ? 8  
HELX_P HELX_P12 AB3 SER A 261 ? LEU A 272 ? SER A 260 LEU A 271 1 ? 12 
HELX_P HELX_P13 AB4 ARG A 275 ? ARG A 279 ? ARG A 274 ARG A 278 5 ? 5  
HELX_P HELX_P14 AB5 THR A 281 ? ASN A 287 ? THR A 280 ASN A 286 1 ? 7  
HELX_P HELX_P15 AB6 HIS A 288 ? GLN A 292 ? HIS A 287 GLN A 291 5 ? 5  
HELX_P HELX_P16 AB7 LEU A 296 ? LEU A 305 ? LEU A 295 LEU A 304 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A SER 261 C ? ? ? 1_555 A SEP 262 N ? ? A SER 260 A SEP 261 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale2 covale both ? A SEP 262 C ? ? ? 1_555 A GLU 263 N ? ? A SEP 261 A GLU 262 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      SEP 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       262 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       SEP 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        261 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                SER 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        SEP 
_pdbx_modification_feature.type                               Phosphorylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           125 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            124 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    126 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     125 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -2.65 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 39  ? LEU A 44  ? TYR A 38  LEU A 43  
AA1 2 SER A 52  ? ARG A 58  ? SER A 51  ARG A 57  
AA1 3 PRO A 64  ? GLU A 71  ? PRO A 63  GLU A 70  
AA1 4 SER A 116 ? GLU A 122 ? SER A 115 GLU A 121 
AA1 5 LEU A 107 ? GLU A 112 ? LEU A 106 GLU A 111 
AA2 1 TRP A 78  ? GLU A 80  ? TRP A 77  GLU A 79  
AA2 2 ARG A 86  ? PRO A 88  ? ARG A 85  PRO A 87  
AA3 1 VAL A 127 ? ASP A 129 ? VAL A 126 ASP A 128 
AA3 2 ILE A 174 ? ASP A 177 ? ILE A 173 ASP A 176 
AA3 3 GLU A 182 ? LEU A 185 ? GLU A 181 LEU A 184 
AA4 1 VAL A 164 ? LEU A 165 ? VAL A 163 LEU A 164 
AA4 2 ALA A 192 ? LEU A 193 ? ALA A 191 LEU A 192 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 42  ? N GLY A 41  O SER A 55  ? O SER A 54  
AA1 2 3 N TYR A 54  ? N TYR A 53  O ILE A 67  ? O ILE A 66  
AA1 3 4 N ALA A 66  ? N ALA A 65  O LEU A 121 ? O LEU A 120 
AA1 4 5 O ILE A 120 ? O ILE A 119 N LEU A 108 ? N LEU A 107 
AA2 1 2 N GLY A 79  ? N GLY A 78  O VAL A 87  ? O VAL A 86  
AA3 1 2 N GLN A 128 ? N GLN A 127 O ILE A 176 ? O ILE A 175 
AA3 2 3 N ASP A 177 ? N ASP A 176 O GLU A 182 ? O GLU A 181 
AA4 1 2 N LEU A 165 ? N LEU A 164 O ALA A 192 ? O ALA A 191 
# 
_pdbx_entry_details.entry_id                   8R0W 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 60  ? ? -154.26 10.80 
2 1 ASP A 167 ? ? -148.90 42.83 
3 1 ASP A 186 ? ? 65.97   82.46 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    SEP 
_pdbx_struct_mod_residue.label_seq_id     262 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     SEP 
_pdbx_struct_mod_residue.auth_seq_id      261 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   SER 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z         
2 x-y,x,z+5/6   
3 y,-x+y,z+1/6  
4 -y,x-y,z+2/3  
5 -x+y,-x,z+1/3 
6 -x,-y,z+1/2   
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -76.4921509166 -114.386604524 -3.60389562565 0.62347169832  ? 0.0728005935357  ? 0.0289009273254 ? 
0.665496917527 ? -0.110703329614  ? 0.714862045298 ? 0.0174906609224 ? -0.0132289400588 ? -0.016403210356  ? 0.0338716228601 ? 
0.0429884850944 ? 0.0526882809157 ? -0.100589197787 ? -0.182287825756  ? 0.214327717291   ? 0.434510852619  ? -0.170651933446  ? 
0.248061328785   ? 0.265236612894  ? 0.245701821535   ? 0.000147776523616  ? 
2 'X-RAY DIFFRACTION' ? refined -67.6280859925 -113.512637896 -11.3443934321 0.431175518452 ? 0.0609888676181  ? 0.0388167548696 ? 
0.495737939376 ? 0.0309758090433  ? 0.430744362435 ? 0.386098550502  ? 0.0752303741789  ? 0.0601563388742  ? 0.574700031761  ? 
0.065740283743  ? 0.424834095033  ? 0.380908081696  ? 0.187264813982   ? 0.109785625661   ? -0.328329474134 ? -0.471209600288  ? 
0.164299057849   ? -0.194781615566 ? -0.188648664021  ? -0.000235415120645 ? 
3 'X-RAY DIFFRACTION' ? refined -51.7413868947 -126.682979483 0.724650011348 0.26408746714  ? -0.0143580648431 ? 0.0206505660077 ? 
0.26267528793  ? 0.00345699292997 ? 0.253238230032 ? 1.23996444589   ? -0.76841689674   ? 0.152929730736   ? 1.09000548939   ? 
-0.144024734651 ? 1.48703556232   ? 0.0248942926131 ? -0.0286572950005 ? 0.0525061267383  ? 0.0765481521668 ? 0.0430735118427  ? 
-0.0590032494777 ? 0.068051570189  ? -0.0110109611837 ? 9.73745292004e-05  ? 
4 'X-RAY DIFFRACTION' ? refined -56.0409626629 -118.645954493 12.774445574   0.592918550936 ? 0.112452159458   ? 0.0411306955753 ? 
0.454527745166 ? -0.0339577792879 ? 0.454431973671 ? 0.0142489425365 ? -0.0280739347993 ? -0.0175711620149 ? 0.0554196903124 ? 
0.0359802160781 ? 0.0243505607424 ? 0.188651597506  ? -0.315132538893  ? -0.0394140947305 ? 0.260328287745  ? -0.0415194851566 ? 
-0.134866209137  ? -0.306448257305 ? 0.100860529225   ? 0.000811199120129  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1  A 33  ? A 18  A 50  ? ? 
;chain 'A' and (resid 33 through 50 )
;
2 'X-RAY DIFFRACTION' 2 A 19 A 51  ? A 82  A 114 ? ? 
;chain 'A' and (resid 51 through 114 )
;
3 'X-RAY DIFFRACTION' 3 A 83 A 115 ? A 273 A 305 ? ? 
;chain 'A' and (resid 115 through 305 )
;
4 'X-RAY DIFFRACTION' 4 C 1  B 2   ? C 8   B 9   ? ? 
;chain 'B' and (resid 2 through 9 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER 0   ? A SER 1   
2  1 Y 1 A MET 1   ? A MET 2   
3  1 Y 1 A LEU 2   ? A LEU 3   
4  1 Y 1 A LEU 3   ? A LEU 4   
5  1 Y 1 A SER 4   ? A SER 5   
6  1 Y 1 A LYS 5   ? A LYS 6   
7  1 Y 1 A ILE 6   ? A ILE 7   
8  1 Y 1 A ASN 7   ? A ASN 8   
9  1 Y 1 A SER 8   ? A SER 9   
10 1 Y 1 A LEU 9   ? A LEU 10  
11 1 Y 1 A ALA 10  ? A ALA 11  
12 1 Y 1 A HIS 11  ? A HIS 12  
13 1 Y 1 A LEU 12  ? A LEU 13  
14 1 Y 1 A ARG 13  ? A ARG 14  
15 1 Y 1 A ALA 14  ? A ALA 15  
16 1 Y 1 A ALA 15  ? A ALA 16  
17 1 Y 1 A PRO 16  ? A PRO 17  
18 1 Y 1 A CYS 17  ? A CYS 18  
19 1 Y 1 A ASN 18  ? A ASN 19  
20 1 Y 1 A ASP 19  ? A ASP 20  
21 1 Y 1 A LEU 20  ? A LEU 21  
22 1 Y 1 A HIS 21  ? A HIS 22  
23 1 Y 1 A ALA 22  ? A ALA 23  
24 1 Y 1 A THR 23  ? A THR 24  
25 1 Y 1 A LYS 24  ? A LYS 25  
26 1 Y 1 A LEU 25  ? A LEU 26  
27 1 Y 1 A ALA 26  ? A ALA 27  
28 1 Y 1 A PRO 27  ? A PRO 28  
29 1 Y 1 A GLY 28  ? A GLY 29  
30 1 Y 1 A LYS 29  ? A LYS 30  
31 1 Y 1 A GLU 30  ? A GLU 31  
32 1 Y 1 A LYS 31  ? A LYS 32  
33 1 Y 1 A GLU 32  ? A GLU 33  
34 1 Y 1 A SER 306 ? A SER 307 
35 1 Y 1 A LEU 307 ? A LEU 308 
36 1 Y 1 A SER 308 ? A SER 309 
37 1 Y 1 A PRO 309 ? A PRO 310 
38 1 Y 1 A GLY 310 ? A GLY 311 
39 1 Y 1 A PRO 311 ? A PRO 312 
40 1 Y 1 A SER 312 ? A SER 313 
41 1 Y 1 B ALA 1   ? B ALA 1   
42 1 Y 1 B GLY 10  ? B GLY 10  
43 1 Y 1 B PRO 11  ? B PRO 11  
44 1 Y 1 B PRO 12  ? B PRO 12  
45 1 Y 1 B THR 13  ? B THR 13  
46 1 Y 1 B ALA 14  ? B ALA 14  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
EDO C1   C  N N 88  
EDO O1   O  N N 89  
EDO C2   C  N N 90  
EDO O2   O  N N 91  
EDO H11  H  N N 92  
EDO H12  H  N N 93  
EDO HO1  H  N N 94  
EDO H21  H  N N 95  
EDO H22  H  N N 96  
EDO HO2  H  N N 97  
GLN N    N  N N 98  
GLN CA   C  N S 99  
GLN C    C  N N 100 
GLN O    O  N N 101 
GLN CB   C  N N 102 
GLN CG   C  N N 103 
GLN CD   C  N N 104 
GLN OE1  O  N N 105 
GLN NE2  N  N N 106 
GLN OXT  O  N N 107 
GLN H    H  N N 108 
GLN H2   H  N N 109 
GLN HA   H  N N 110 
GLN HB2  H  N N 111 
GLN HB3  H  N N 112 
GLN HG2  H  N N 113 
GLN HG3  H  N N 114 
GLN HE21 H  N N 115 
GLN HE22 H  N N 116 
GLN HXT  H  N N 117 
GLU N    N  N N 118 
GLU CA   C  N S 119 
GLU C    C  N N 120 
GLU O    O  N N 121 
GLU CB   C  N N 122 
GLU CG   C  N N 123 
GLU CD   C  N N 124 
GLU OE1  O  N N 125 
GLU OE2  O  N N 126 
GLU OXT  O  N N 127 
GLU H    H  N N 128 
GLU H2   H  N N 129 
GLU HA   H  N N 130 
GLU HB2  H  N N 131 
GLU HB3  H  N N 132 
GLU HG2  H  N N 133 
GLU HG3  H  N N 134 
GLU HE2  H  N N 135 
GLU HXT  H  N N 136 
GLY N    N  N N 137 
GLY CA   C  N N 138 
GLY C    C  N N 139 
GLY O    O  N N 140 
GLY OXT  O  N N 141 
GLY H    H  N N 142 
GLY H2   H  N N 143 
GLY HA2  H  N N 144 
GLY HA3  H  N N 145 
GLY HXT  H  N N 146 
GOL C1   C  N N 147 
GOL O1   O  N N 148 
GOL C2   C  N N 149 
GOL O2   O  N N 150 
GOL C3   C  N N 151 
GOL O3   O  N N 152 
GOL H11  H  N N 153 
GOL H12  H  N N 154 
GOL HO1  H  N N 155 
GOL H2   H  N N 156 
GOL HO2  H  N N 157 
GOL H31  H  N N 158 
GOL H32  H  N N 159 
GOL HO3  H  N N 160 
HIS N    N  N N 161 
HIS CA   C  N S 162 
HIS C    C  N N 163 
HIS O    O  N N 164 
HIS CB   C  N N 165 
HIS CG   C  Y N 166 
HIS ND1  N  Y N 167 
HIS CD2  C  Y N 168 
HIS CE1  C  Y N 169 
HIS NE2  N  Y N 170 
HIS OXT  O  N N 171 
HIS H    H  N N 172 
HIS H2   H  N N 173 
HIS HA   H  N N 174 
HIS HB2  H  N N 175 
HIS HB3  H  N N 176 
HIS HD1  H  N N 177 
HIS HD2  H  N N 178 
HIS HE1  H  N N 179 
HIS HE2  H  N N 180 
HIS HXT  H  N N 181 
HOH O    O  N N 182 
HOH H1   H  N N 183 
HOH H2   H  N N 184 
ILE N    N  N N 185 
ILE CA   C  N S 186 
ILE C    C  N N 187 
ILE O    O  N N 188 
ILE CB   C  N S 189 
ILE CG1  C  N N 190 
ILE CG2  C  N N 191 
ILE CD1  C  N N 192 
ILE OXT  O  N N 193 
ILE H    H  N N 194 
ILE H2   H  N N 195 
ILE HA   H  N N 196 
ILE HB   H  N N 197 
ILE HG12 H  N N 198 
ILE HG13 H  N N 199 
ILE HG21 H  N N 200 
ILE HG22 H  N N 201 
ILE HG23 H  N N 202 
ILE HD11 H  N N 203 
ILE HD12 H  N N 204 
ILE HD13 H  N N 205 
ILE HXT  H  N N 206 
LEU N    N  N N 207 
LEU CA   C  N S 208 
LEU C    C  N N 209 
LEU O    O  N N 210 
LEU CB   C  N N 211 
LEU CG   C  N N 212 
LEU CD1  C  N N 213 
LEU CD2  C  N N 214 
LEU OXT  O  N N 215 
LEU H    H  N N 216 
LEU H2   H  N N 217 
LEU HA   H  N N 218 
LEU HB2  H  N N 219 
LEU HB3  H  N N 220 
LEU HG   H  N N 221 
LEU HD11 H  N N 222 
LEU HD12 H  N N 223 
LEU HD13 H  N N 224 
LEU HD21 H  N N 225 
LEU HD22 H  N N 226 
LEU HD23 H  N N 227 
LEU HXT  H  N N 228 
LYS N    N  N N 229 
LYS CA   C  N S 230 
LYS C    C  N N 231 
LYS O    O  N N 232 
LYS CB   C  N N 233 
LYS CG   C  N N 234 
LYS CD   C  N N 235 
LYS CE   C  N N 236 
LYS NZ   N  N N 237 
LYS OXT  O  N N 238 
LYS H    H  N N 239 
LYS H2   H  N N 240 
LYS HA   H  N N 241 
LYS HB2  H  N N 242 
LYS HB3  H  N N 243 
LYS HG2  H  N N 244 
LYS HG3  H  N N 245 
LYS HD2  H  N N 246 
LYS HD3  H  N N 247 
LYS HE2  H  N N 248 
LYS HE3  H  N N 249 
LYS HZ1  H  N N 250 
LYS HZ2  H  N N 251 
LYS HZ3  H  N N 252 
LYS HXT  H  N N 253 
MET N    N  N N 254 
MET CA   C  N S 255 
MET C    C  N N 256 
MET O    O  N N 257 
MET CB   C  N N 258 
MET CG   C  N N 259 
MET SD   S  N N 260 
MET CE   C  N N 261 
MET OXT  O  N N 262 
MET H    H  N N 263 
MET H2   H  N N 264 
MET HA   H  N N 265 
MET HB2  H  N N 266 
MET HB3  H  N N 267 
MET HG2  H  N N 268 
MET HG3  H  N N 269 
MET HE1  H  N N 270 
MET HE2  H  N N 271 
MET HE3  H  N N 272 
MET HXT  H  N N 273 
PHE N    N  N N 274 
PHE CA   C  N S 275 
PHE C    C  N N 276 
PHE O    O  N N 277 
PHE CB   C  N N 278 
PHE CG   C  Y N 279 
PHE CD1  C  Y N 280 
PHE CD2  C  Y N 281 
PHE CE1  C  Y N 282 
PHE CE2  C  Y N 283 
PHE CZ   C  Y N 284 
PHE OXT  O  N N 285 
PHE H    H  N N 286 
PHE H2   H  N N 287 
PHE HA   H  N N 288 
PHE HB2  H  N N 289 
PHE HB3  H  N N 290 
PHE HD1  H  N N 291 
PHE HD2  H  N N 292 
PHE HE1  H  N N 293 
PHE HE2  H  N N 294 
PHE HZ   H  N N 295 
PHE HXT  H  N N 296 
PRO N    N  N N 297 
PRO CA   C  N S 298 
PRO C    C  N N 299 
PRO O    O  N N 300 
PRO CB   C  N N 301 
PRO CG   C  N N 302 
PRO CD   C  N N 303 
PRO OXT  O  N N 304 
PRO H    H  N N 305 
PRO HA   H  N N 306 
PRO HB2  H  N N 307 
PRO HB3  H  N N 308 
PRO HG2  H  N N 309 
PRO HG3  H  N N 310 
PRO HD2  H  N N 311 
PRO HD3  H  N N 312 
PRO HXT  H  N N 313 
SEP N    N  N N 314 
SEP CA   C  N S 315 
SEP CB   C  N N 316 
SEP OG   O  N N 317 
SEP C    C  N N 318 
SEP O    O  N N 319 
SEP OXT  O  N N 320 
SEP P    P  N N 321 
SEP O1P  O  N N 322 
SEP O2P  O  N N 323 
SEP O3P  O  N N 324 
SEP H    H  N N 325 
SEP H2   H  N N 326 
SEP HA   H  N N 327 
SEP HB2  H  N N 328 
SEP HB3  H  N N 329 
SEP HXT  H  N N 330 
SEP HOP2 H  N N 331 
SEP HOP3 H  N N 332 
SER N    N  N N 333 
SER CA   C  N S 334 
SER C    C  N N 335 
SER O    O  N N 336 
SER CB   C  N N 337 
SER OG   O  N N 338 
SER OXT  O  N N 339 
SER H    H  N N 340 
SER H2   H  N N 341 
SER HA   H  N N 342 
SER HB2  H  N N 343 
SER HB3  H  N N 344 
SER HG   H  N N 345 
SER HXT  H  N N 346 
THR N    N  N N 347 
THR CA   C  N S 348 
THR C    C  N N 349 
THR O    O  N N 350 
THR CB   C  N R 351 
THR OG1  O  N N 352 
THR CG2  C  N N 353 
THR OXT  O  N N 354 
THR H    H  N N 355 
THR H2   H  N N 356 
THR HA   H  N N 357 
THR HB   H  N N 358 
THR HG1  H  N N 359 
THR HG21 H  N N 360 
THR HG22 H  N N 361 
THR HG23 H  N N 362 
THR HXT  H  N N 363 
TRP N    N  N N 364 
TRP CA   C  N S 365 
TRP C    C  N N 366 
TRP O    O  N N 367 
TRP CB   C  N N 368 
TRP CG   C  Y N 369 
TRP CD1  C  Y N 370 
TRP CD2  C  Y N 371 
TRP NE1  N  Y N 372 
TRP CE2  C  Y N 373 
TRP CE3  C  Y N 374 
TRP CZ2  C  Y N 375 
TRP CZ3  C  Y N 376 
TRP CH2  C  Y N 377 
TRP OXT  O  N N 378 
TRP H    H  N N 379 
TRP H2   H  N N 380 
TRP HA   H  N N 381 
TRP HB2  H  N N 382 
TRP HB3  H  N N 383 
TRP HD1  H  N N 384 
TRP HE1  H  N N 385 
TRP HE3  H  N N 386 
TRP HZ2  H  N N 387 
TRP HZ3  H  N N 388 
TRP HH2  H  N N 389 
TRP HXT  H  N N 390 
TYR N    N  N N 391 
TYR CA   C  N S 392 
TYR C    C  N N 393 
TYR O    O  N N 394 
TYR CB   C  N N 395 
TYR CG   C  Y N 396 
TYR CD1  C  Y N 397 
TYR CD2  C  Y N 398 
TYR CE1  C  Y N 399 
TYR CE2  C  Y N 400 
TYR CZ   C  Y N 401 
TYR OH   O  N N 402 
TYR OXT  O  N N 403 
TYR H    H  N N 404 
TYR H2   H  N N 405 
TYR HA   H  N N 406 
TYR HB2  H  N N 407 
TYR HB3  H  N N 408 
TYR HD1  H  N N 409 
TYR HD2  H  N N 410 
TYR HE1  H  N N 411 
TYR HE2  H  N N 412 
TYR HH   H  N N 413 
TYR HXT  H  N N 414 
VAL N    N  N N 415 
VAL CA   C  N S 416 
VAL C    C  N N 417 
VAL O    O  N N 418 
VAL CB   C  N N 419 
VAL CG1  C  N N 420 
VAL CG2  C  N N 421 
VAL OXT  O  N N 422 
VAL H    H  N N 423 
VAL H2   H  N N 424 
VAL HA   H  N N 425 
VAL HB   H  N N 426 
VAL HG11 H  N N 427 
VAL HG12 H  N N 428 
VAL HG13 H  N N 429 
VAL HG21 H  N N 430 
VAL HG22 H  N N 431 
VAL HG23 H  N N 432 
VAL HXT  H  N N 433 
XGF C10  C  Y N 434 
XGF C2   C  Y N 435 
XGF C4   C  Y N 436 
XGF C5   C  Y N 437 
XGF C6   C  Y N 438 
XGF C8   C  Y N 439 
XGF C9   C  Y N 440 
XGF N1   N  N N 441 
XGF N3   N  Y N 442 
XGF O11  O  Y N 443 
XGF BR7  BR N N 444 
XGF H5   H  N N 445 
XGF H8   H  N N 446 
XGF H9   H  N N 447 
XGF H1A  H  N N 448 
XGF H1B  H  N N 449 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
GOL C1  O1   sing N N 138 
GOL C1  C2   sing N N 139 
GOL C1  H11  sing N N 140 
GOL C1  H12  sing N N 141 
GOL O1  HO1  sing N N 142 
GOL C2  O2   sing N N 143 
GOL C2  C3   sing N N 144 
GOL C2  H2   sing N N 145 
GOL O2  HO2  sing N N 146 
GOL C3  O3   sing N N 147 
GOL C3  H31  sing N N 148 
GOL C3  H32  sing N N 149 
GOL O3  HO3  sing N N 150 
HIS N   CA   sing N N 151 
HIS N   H    sing N N 152 
HIS N   H2   sing N N 153 
HIS CA  C    sing N N 154 
HIS CA  CB   sing N N 155 
HIS CA  HA   sing N N 156 
HIS C   O    doub N N 157 
HIS C   OXT  sing N N 158 
HIS CB  CG   sing N N 159 
HIS CB  HB2  sing N N 160 
HIS CB  HB3  sing N N 161 
HIS CG  ND1  sing Y N 162 
HIS CG  CD2  doub Y N 163 
HIS ND1 CE1  doub Y N 164 
HIS ND1 HD1  sing N N 165 
HIS CD2 NE2  sing Y N 166 
HIS CD2 HD2  sing N N 167 
HIS CE1 NE2  sing Y N 168 
HIS CE1 HE1  sing N N 169 
HIS NE2 HE2  sing N N 170 
HIS OXT HXT  sing N N 171 
HOH O   H1   sing N N 172 
HOH O   H2   sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MET N   CA   sing N N 240 
MET N   H    sing N N 241 
MET N   H2   sing N N 242 
MET CA  C    sing N N 243 
MET CA  CB   sing N N 244 
MET CA  HA   sing N N 245 
MET C   O    doub N N 246 
MET C   OXT  sing N N 247 
MET CB  CG   sing N N 248 
MET CB  HB2  sing N N 249 
MET CB  HB3  sing N N 250 
MET CG  SD   sing N N 251 
MET CG  HG2  sing N N 252 
MET CG  HG3  sing N N 253 
MET SD  CE   sing N N 254 
MET CE  HE1  sing N N 255 
MET CE  HE2  sing N N 256 
MET CE  HE3  sing N N 257 
MET OXT HXT  sing N N 258 
PHE N   CA   sing N N 259 
PHE N   H    sing N N 260 
PHE N   H2   sing N N 261 
PHE CA  C    sing N N 262 
PHE CA  CB   sing N N 263 
PHE CA  HA   sing N N 264 
PHE C   O    doub N N 265 
PHE C   OXT  sing N N 266 
PHE CB  CG   sing N N 267 
PHE CB  HB2  sing N N 268 
PHE CB  HB3  sing N N 269 
PHE CG  CD1  doub Y N 270 
PHE CG  CD2  sing Y N 271 
PHE CD1 CE1  sing Y N 272 
PHE CD1 HD1  sing N N 273 
PHE CD2 CE2  doub Y N 274 
PHE CD2 HD2  sing N N 275 
PHE CE1 CZ   doub Y N 276 
PHE CE1 HE1  sing N N 277 
PHE CE2 CZ   sing Y N 278 
PHE CE2 HE2  sing N N 279 
PHE CZ  HZ   sing N N 280 
PHE OXT HXT  sing N N 281 
PRO N   CA   sing N N 282 
PRO N   CD   sing N N 283 
PRO N   H    sing N N 284 
PRO CA  C    sing N N 285 
PRO CA  CB   sing N N 286 
PRO CA  HA   sing N N 287 
PRO C   O    doub N N 288 
PRO C   OXT  sing N N 289 
PRO CB  CG   sing N N 290 
PRO CB  HB2  sing N N 291 
PRO CB  HB3  sing N N 292 
PRO CG  CD   sing N N 293 
PRO CG  HG2  sing N N 294 
PRO CG  HG3  sing N N 295 
PRO CD  HD2  sing N N 296 
PRO CD  HD3  sing N N 297 
PRO OXT HXT  sing N N 298 
SEP N   CA   sing N N 299 
SEP N   H    sing N N 300 
SEP N   H2   sing N N 301 
SEP CA  CB   sing N N 302 
SEP CA  C    sing N N 303 
SEP CA  HA   sing N N 304 
SEP CB  OG   sing N N 305 
SEP CB  HB2  sing N N 306 
SEP CB  HB3  sing N N 307 
SEP OG  P    sing N N 308 
SEP C   O    doub N N 309 
SEP C   OXT  sing N N 310 
SEP OXT HXT  sing N N 311 
SEP P   O1P  doub N N 312 
SEP P   O2P  sing N N 313 
SEP P   O3P  sing N N 314 
SEP O2P HOP2 sing N N 315 
SEP O3P HOP3 sing N N 316 
SER N   CA   sing N N 317 
SER N   H    sing N N 318 
SER N   H2   sing N N 319 
SER CA  C    sing N N 320 
SER CA  CB   sing N N 321 
SER CA  HA   sing N N 322 
SER C   O    doub N N 323 
SER C   OXT  sing N N 324 
SER CB  OG   sing N N 325 
SER CB  HB2  sing N N 326 
SER CB  HB3  sing N N 327 
SER OG  HG   sing N N 328 
SER OXT HXT  sing N N 329 
THR N   CA   sing N N 330 
THR N   H    sing N N 331 
THR N   H2   sing N N 332 
THR CA  C    sing N N 333 
THR CA  CB   sing N N 334 
THR CA  HA   sing N N 335 
THR C   O    doub N N 336 
THR C   OXT  sing N N 337 
THR CB  OG1  sing N N 338 
THR CB  CG2  sing N N 339 
THR CB  HB   sing N N 340 
THR OG1 HG1  sing N N 341 
THR CG2 HG21 sing N N 342 
THR CG2 HG22 sing N N 343 
THR CG2 HG23 sing N N 344 
THR OXT HXT  sing N N 345 
TRP N   CA   sing N N 346 
TRP N   H    sing N N 347 
TRP N   H2   sing N N 348 
TRP CA  C    sing N N 349 
TRP CA  CB   sing N N 350 
TRP CA  HA   sing N N 351 
TRP C   O    doub N N 352 
TRP C   OXT  sing N N 353 
TRP CB  CG   sing N N 354 
TRP CB  HB2  sing N N 355 
TRP CB  HB3  sing N N 356 
TRP CG  CD1  doub Y N 357 
TRP CG  CD2  sing Y N 358 
TRP CD1 NE1  sing Y N 359 
TRP CD1 HD1  sing N N 360 
TRP CD2 CE2  doub Y N 361 
TRP CD2 CE3  sing Y N 362 
TRP NE1 CE2  sing Y N 363 
TRP NE1 HE1  sing N N 364 
TRP CE2 CZ2  sing Y N 365 
TRP CE3 CZ3  doub Y N 366 
TRP CE3 HE3  sing N N 367 
TRP CZ2 CH2  doub Y N 368 
TRP CZ2 HZ2  sing N N 369 
TRP CZ3 CH2  sing Y N 370 
TRP CZ3 HZ3  sing N N 371 
TRP CH2 HH2  sing N N 372 
TRP OXT HXT  sing N N 373 
TYR N   CA   sing N N 374 
TYR N   H    sing N N 375 
TYR N   H2   sing N N 376 
TYR CA  C    sing N N 377 
TYR CA  CB   sing N N 378 
TYR CA  HA   sing N N 379 
TYR C   O    doub N N 380 
TYR C   OXT  sing N N 381 
TYR CB  CG   sing N N 382 
TYR CB  HB2  sing N N 383 
TYR CB  HB3  sing N N 384 
TYR CG  CD1  doub Y N 385 
TYR CG  CD2  sing Y N 386 
TYR CD1 CE1  sing Y N 387 
TYR CD1 HD1  sing N N 388 
TYR CD2 CE2  doub Y N 389 
TYR CD2 HD2  sing N N 390 
TYR CE1 CZ   doub Y N 391 
TYR CE1 HE1  sing N N 392 
TYR CE2 CZ   sing Y N 393 
TYR CE2 HE2  sing N N 394 
TYR CZ  OH   sing N N 395 
TYR OH  HH   sing N N 396 
TYR OXT HXT  sing N N 397 
VAL N   CA   sing N N 398 
VAL N   H    sing N N 399 
VAL N   H2   sing N N 400 
VAL CA  C    sing N N 401 
VAL CA  CB   sing N N 402 
VAL CA  HA   sing N N 403 
VAL C   O    doub N N 404 
VAL C   OXT  sing N N 405 
VAL CB  CG1  sing N N 406 
VAL CB  CG2  sing N N 407 
VAL CB  HB   sing N N 408 
VAL CG1 HG11 sing N N 409 
VAL CG1 HG12 sing N N 410 
VAL CG1 HG13 sing N N 411 
VAL CG2 HG21 sing N N 412 
VAL CG2 HG22 sing N N 413 
VAL CG2 HG23 sing N N 414 
VAL OXT HXT  sing N N 415 
XGF N1  C2   sing N N 416 
XGF C2  N3   doub Y N 417 
XGF N3  C4   sing Y N 418 
XGF C4  C5   doub Y N 419 
XGF C5  C6   sing Y N 420 
XGF C6  BR7  sing N N 421 
XGF C6  C8   doub Y N 422 
XGF C8  C9   sing Y N 423 
XGF C9  C10  doub Y N 424 
XGF C10 O11  sing Y N 425 
XGF O11 C2   sing Y N 426 
XGF C10 C4   sing Y N 427 
XGF C5  H5   sing N N 428 
XGF C8  H8   sing N N 429 
XGF C9  H9   sing N N 430 
XGF N1  H1A  sing N N 431 
XGF N1  H1B  sing N N 432 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5NDT 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 65' 
_space_group.name_Hall        'P 65' 
_space_group.IT_number        170 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8R0W 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010391 
_atom_sites.fract_transf_matrix[1][2]   0.005999 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011998 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012526 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
BR ? ? 25.79822 9.11301 ? ? 1.35700  25.34896 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135  5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . PRO A 1 34  ? -79.99915 -109.44817 -16.89605 1.000 101.18237 ? 33  PRO A N   1 
ATOM   2    C  CA  . PRO A 1 34  ? -80.42108 -108.85126 -15.62276 1.000 102.90978 ? 33  PRO A CA  1 
ATOM   3    C  C   . PRO A 1 34  ? -80.25971 -109.81473 -14.44674 1.000 97.99647  ? 33  PRO A C   1 
ATOM   4    O  O   . PRO A 1 34  ? -80.72858 -110.95117 -14.51634 1.000 95.75236  ? 33  PRO A O   1 
ATOM   5    C  CB  . PRO A 1 34  ? -81.89522 -108.51932 -15.86683 1.000 98.04761  ? 33  PRO A CB  1 
ATOM   6    C  CG  . PRO A 1 34  ? -81.97746 -108.29170 -17.33997 1.000 96.44966  ? 33  PRO A CG  1 
ATOM   7    C  CD  . PRO A 1 34  ? -81.00373 -109.25943 -17.95725 1.000 96.50387  ? 33  PRO A CD  1 
ATOM   8    N  N   . LEU A 1 35  ? -79.60831 -109.35406 -13.37792 1.000 97.47775  ? 34  LEU A N   1 
ATOM   9    C  CA  . LEU A 1 35  ? -79.28062 -110.21024 -12.24251 1.000 96.08184  ? 34  LEU A CA  1 
ATOM   10   C  C   . LEU A 1 35  ? -80.52482 -110.67990 -11.49450 1.000 93.33298  ? 34  LEU A C   1 
ATOM   11   O  O   . LEU A 1 35  ? -80.81674 -111.88001 -11.47061 1.000 82.66340  ? 34  LEU A O   1 
ATOM   12   C  CB  . LEU A 1 35  ? -78.33363 -109.48410 -11.28193 1.000 89.28916  ? 34  LEU A CB  1 
ATOM   13   N  N   . GLU A 1 36  ? -81.26219 -109.74918 -10.87864 1.000 96.62128  ? 35  GLU A N   1 
ATOM   14   C  CA  . GLU A 1 36  ? -82.40624 -110.13074 -10.05444 1.000 91.24488  ? 35  GLU A CA  1 
ATOM   15   C  C   . GLU A 1 36  ? -83.48080 -110.86257 -10.84970 1.000 90.43923  ? 35  GLU A C   1 
ATOM   16   O  O   . GLU A 1 36  ? -84.27484 -111.60436 -10.25943 1.000 85.28044  ? 35  GLU A O   1 
ATOM   17   C  CB  . GLU A 1 36  ? -83.00742 -108.89452 -9.38107  1.000 88.20142  ? 35  GLU A CB  1 
ATOM   18   N  N   . SER A 1 37  ? -83.51616 -110.68249 -12.17153 1.000 91.94535  ? 36  SER A N   1 
ATOM   19   C  CA  . SER A 1 37  ? -84.51269 -111.31874 -13.02394 1.000 91.00863  ? 36  SER A CA  1 
ATOM   20   C  C   . SER A 1 37  ? -84.07464 -112.67946 -13.54582 1.000 88.39848  ? 36  SER A C   1 
ATOM   21   O  O   . SER A 1 37  ? -84.89324 -113.39387 -14.13348 1.000 86.20133  ? 36  SER A O   1 
ATOM   22   C  CB  . SER A 1 37  ? -84.85178 -110.41057 -14.21053 1.000 91.61427  ? 36  SER A CB  1 
ATOM   23   N  N   . GLN A 1 38  ? -82.81045 -113.05218 -13.35143 1.000 82.29590  ? 37  GLN A N   1 
ATOM   24   C  CA  . GLN A 1 38  ? -82.30239 -114.34153 -13.79233 1.000 73.48779  ? 37  GLN A CA  1 
ATOM   25   C  C   . GLN A 1 38  ? -81.97288 -115.28392 -12.64254 1.000 68.20395  ? 37  GLN A C   1 
ATOM   26   O  O   . GLN A 1 38  ? -81.83463 -116.49076 -12.87268 1.000 63.77067  ? 37  GLN A O   1 
ATOM   27   C  CB  . GLN A 1 38  ? -81.05052 -114.13809 -14.65921 1.000 73.31646  ? 37  GLN A CB  1 
ATOM   28   C  CG  . GLN A 1 38  ? -80.69697 -115.29870 -15.56301 1.000 73.88052  ? 37  GLN A CG  1 
ATOM   29   C  CD  . GLN A 1 38  ? -79.53764 -114.97256 -16.48678 1.000 74.81147  ? 37  GLN A CD  1 
ATOM   30   O  OE1 . GLN A 1 38  ? -79.27096 -113.80642 -16.77937 1.000 77.76153  ? 37  GLN A OE1 1 
ATOM   31   N  NE2 . GLN A 1 38  ? -78.84189 -116.00212 -16.94843 1.000 64.99256  ? 37  GLN A NE2 1 
ATOM   32   N  N   . TYR A 1 39  ? -81.85240 -114.76553 -11.42006 1.000 64.68558  ? 38  TYR A N   1 
ATOM   33   C  CA  . TYR A 1 39  ? -81.54729 -115.55501 -10.23698 1.000 56.81604  ? 38  TYR A CA  1 
ATOM   34   C  C   . TYR A 1 39  ? -82.48187 -115.15741 -9.10916  1.000 61.36905  ? 38  TYR A C   1 
ATOM   35   O  O   . TYR A 1 39  ? -82.76028 -113.97001 -8.90975  1.000 61.61193  ? 38  TYR A O   1 
ATOM   36   C  CB  . TYR A 1 39  ? -80.08657 -115.35768 -9.78274  1.000 57.48059  ? 38  TYR A CB  1 
ATOM   37   C  CG  . TYR A 1 39  ? -79.09016 -115.82918 -10.80928 1.000 50.39999  ? 38  TYR A CG  1 
ATOM   38   C  CD1 . TYR A 1 39  ? -78.67053 -114.98932 -11.83021 1.000 53.92245  ? 38  TYR A CD1 1 
ATOM   39   C  CD2 . TYR A 1 39  ? -78.59662 -117.12079 -10.77735 1.000 49.37523  ? 38  TYR A CD2 1 
ATOM   40   C  CE1 . TYR A 1 39  ? -77.78109 -115.41864 -12.78795 1.000 51.50458  ? 38  TYR A CE1 1 
ATOM   41   C  CE2 . TYR A 1 39  ? -77.70716 -117.56397 -11.73485 1.000 49.57334  ? 38  TYR A CE2 1 
ATOM   42   C  CZ  . TYR A 1 39  ? -77.30179 -116.70684 -12.73801 1.000 54.51306  ? 38  TYR A CZ  1 
ATOM   43   O  OH  . TYR A 1 39  ? -76.41229 -117.13850 -13.69141 1.000 52.21596  ? 38  TYR A OH  1 
ATOM   44   N  N   . GLN A 1 40  ? -82.97931 -116.15588 -8.38787  1.000 57.40918  ? 39  GLN A N   1 
ATOM   45   C  CA  . GLN A 1 40  ? -83.54608 -115.91252 -7.07101  1.000 59.08102  ? 39  GLN A CA  1 
ATOM   46   C  C   . GLN A 1 40  ? -82.38237 -115.77507 -6.09985  1.000 54.94761  ? 39  GLN A C   1 
ATOM   47   O  O   . GLN A 1 40  ? -81.51440 -116.65276 -6.03792  1.000 53.34523  ? 39  GLN A O   1 
ATOM   48   C  CB  . GLN A 1 40  ? -84.48362 -117.04577 -6.66034  1.000 59.64823  ? 39  GLN A CB  1 
ATOM   49   N  N   . VAL A 1 41  ? -82.33432 -114.66375 -5.37603  1.000 62.28723  ? 40  VAL A N   1 
ATOM   50   C  CA  . VAL A 1 41  ? -81.24363 -114.38918 -4.45048  1.000 57.58472  ? 40  VAL A CA  1 
ATOM   51   C  C   . VAL A 1 41  ? -81.71700 -114.68007 -3.03488  1.000 61.28760  ? 40  VAL A C   1 
ATOM   52   O  O   . VAL A 1 41  ? -82.79131 -114.22291 -2.61575  1.000 53.33071  ? 40  VAL A O   1 
ATOM   53   C  CB  . VAL A 1 41  ? -80.73942 -112.94224 -4.58081  1.000 61.41633  ? 40  VAL A CB  1 
ATOM   54   C  CG1 . VAL A 1 41  ? -79.51690 -112.74715 -3.69225  1.000 62.24494  ? 40  VAL A CG1 1 
ATOM   55   C  CG2 . VAL A 1 41  ? -80.40018 -112.62319 -6.02936  1.000 62.44289  ? 40  VAL A CG2 1 
ATOM   56   N  N   . GLY A 1 42  ? -80.92404 -115.45232 -2.30450  1.000 53.54995  ? 41  GLY A N   1 
ATOM   57   C  CA  . GLY A 1 42  ? -81.23305 -115.77562 -0.93897  1.000 54.34436  ? 41  GLY A CA  1 
ATOM   58   C  C   . GLY A 1 42  ? -80.32976 -115.02880 0.01605   1.000 56.51449  ? 41  GLY A C   1 
ATOM   59   O  O   . GLY A 1 42  ? -79.73880 -113.99877 -0.32561  1.000 54.59323  ? 41  GLY A O   1 
ATOM   60   N  N   . PRO A 1 43  ? -80.18669 -115.55132 1.22839   1.000 56.92784  ? 42  PRO A N   1 
ATOM   61   C  CA  . PRO A 1 43  ? -79.45866 -114.82858 2.27271   1.000 57.39806  ? 42  PRO A CA  1 
ATOM   62   C  C   . PRO A 1 43  ? -77.94643 -114.94697 2.10745   1.000 56.01979  ? 42  PRO A C   1 
ATOM   63   O  O   . PRO A 1 43  ? -77.42596 -115.72458 1.30521   1.000 55.60029  ? 42  PRO A O   1 
ATOM   64   C  CB  . PRO A 1 43  ? -79.92914 -115.51888 3.55429   1.000 56.88538  ? 42  PRO A CB  1 
ATOM   65   C  CG  . PRO A 1 43  ? -80.15322 -116.93571 3.12363   1.000 60.04329  ? 42  PRO A CG  1 
ATOM   66   C  CD  . PRO A 1 43  ? -80.68619 -116.85394 1.70676   1.000 61.64763  ? 42  PRO A CD  1 
ATOM   67   N  N   . LEU A 1 44  ? -77.25226 -114.13753 2.90433   1.000 56.43213  ? 43  LEU A N   1 
ATOM   68   C  CA  . LEU A 1 44  ? -75.79946 -114.16913 2.99382   1.000 56.48428  ? 43  LEU A CA  1 
ATOM   69   C  C   . LEU A 1 44  ? -75.30360 -115.56534 3.35329   1.000 56.76289  ? 43  LEU A C   1 
ATOM   70   O  O   . LEU A 1 44  ? -75.86709 -116.23189 4.22511   1.000 57.29852  ? 43  LEU A O   1 
ATOM   71   C  CB  . LEU A 1 44  ? -75.35432 -113.14938 4.04853   1.000 57.03668  ? 43  LEU A CB  1 
ATOM   72   C  CG  . LEU A 1 44  ? -73.91544 -112.70843 4.28352   1.000 57.15311  ? 43  LEU A CG  1 
ATOM   73   C  CD1 . LEU A 1 44  ? -73.28128 -112.14334 3.00878   1.000 56.39890  ? 43  LEU A CD1 1 
ATOM   74   C  CD2 . LEU A 1 44  ? -73.89251 -111.67360 5.42329   1.000 57.75475  ? 43  LEU A CD2 1 
ATOM   75   N  N   . LEU A 1 45  ? -74.24582 -116.00809 2.66486   1.000 56.39308  ? 44  LEU A N   1 
ATOM   76   C  CA  . LEU A 1 45  ? -73.54399 -117.24610 2.99108   1.000 56.64808  ? 44  LEU A CA  1 
ATOM   77   C  C   . LEU A 1 45  ? -72.42667 -116.96219 3.98287   1.000 57.20778  ? 44  LEU A C   1 
ATOM   78   O  O   . LEU A 1 45  ? -71.70265 -115.97527 3.84534   1.000 58.68177  ? 44  LEU A O   1 
ATOM   79   C  CB  . LEU A 1 45  ? -72.93029 -117.89761 1.74503   1.000 55.96910  ? 44  LEU A CB  1 
ATOM   80   C  CG  . LEU A 1 45  ? -73.74114 -118.78098 0.79938   1.000 55.47155  ? 44  LEU A CG  1 
ATOM   81   C  CD1 . LEU A 1 45  ? -72.84594 -119.34245 -0.30277  1.000 54.87142  ? 44  LEU A CD1 1 
ATOM   82   C  CD2 . LEU A 1 45  ? -74.42780 -119.91333 1.54821   1.000 56.63120  ? 44  LEU A CD2 1 
ATOM   83   N  N   . GLY A 1 46  ? -72.28349 -117.83787 4.97555   1.000 57.82881  ? 45  GLY A N   1 
ATOM   84   C  CA  . GLY A 1 46  ? -71.15922 -117.76061 5.89659   1.000 58.36345  ? 45  GLY A CA  1 
ATOM   85   C  C   . GLY A 1 46  ? -71.03614 -116.47558 6.69434   1.000 58.75419  ? 45  GLY A C   1 
ATOM   86   O  O   . GLY A 1 46  ? -69.95448 -116.18591 7.21429   1.000 59.04816  ? 45  GLY A O   1 
ATOM   87   N  N   . SER A 1 47  ? -72.10929 -115.68464 6.78382   1.000 58.75503  ? 46  SER A N   1 
ATOM   88   C  CA  . SER A 1 47  ? -72.13245 -114.42247 7.52973   1.000 59.11719  ? 46  SER A CA  1 
ATOM   89   C  C   . SER A 1 47  ? -71.03095 -113.44694 7.10588   1.000 58.82972  ? 46  SER A C   1 
ATOM   90   O  O   . SER A 1 47  ? -70.53749 -112.66685 7.92990   1.000 59.26875  ? 46  SER A O   1 
ATOM   91   C  CB  . SER A 1 47  ? -72.05809 -114.67485 9.03878   1.000 60.00320  ? 46  SER A CB  1 
ATOM   92   O  OG  . SER A 1 47  ? -73.23291 -115.31542 9.48579   1.000 60.28988  ? 46  SER A OG  1 
ATOM   93   N  N   . GLY A 1 48  ? -70.65523 -113.45019 5.82110   1.000 58.09333  ? 47  GLY A N   1 
ATOM   94   C  CA  . GLY A 1 48  ? -69.63283 -112.55641 5.31585   1.000 57.76755  ? 47  GLY A CA  1 
ATOM   95   C  C   . GLY A 1 48  ? -68.22445 -113.12072 5.30551   1.000 57.80507  ? 47  GLY A C   1 
ATOM   96   O  O   . GLY A 1 48  ? -67.31400 -112.46697 4.76864   1.000 57.47573  ? 47  GLY A O   1 
ATOM   97   N  N   . GLY A 1 49  ? -68.01783 -114.31428 5.87044   1.000 58.19330  ? 48  GLY A N   1 
ATOM   98   C  CA  . GLY A 1 49  ? -66.68630 -114.88447 5.98886   1.000 58.30836  ? 48  GLY A CA  1 
ATOM   99   C  C   . GLY A 1 49  ? -66.04122 -115.23424 4.66191   1.000 57.56965  ? 48  GLY A C   1 
ATOM   100  O  O   . GLY A 1 49  ? -64.81690 -115.39049 4.60906   1.000 57.56570  ? 48  GLY A O   1 
ATOM   101  N  N   . PHE A 1 50  ? -66.84035 -115.37037 3.59740   1.000 56.95223  ? 49  PHE A N   1 
ATOM   102  C  CA  . PHE A 1 50  ? -66.34961 -115.58513 2.24009   1.000 56.18849  ? 49  PHE A CA  1 
ATOM   103  C  C   . PHE A 1 50  ? -66.24548 -114.29172 1.43783   1.000 55.66586  ? 49  PHE A C   1 
ATOM   104  O  O   . PHE A 1 50  ? -65.81848 -114.32558 0.27718   1.000 55.00817  ? 49  PHE A O   1 
ATOM   105  C  CB  . PHE A 1 50  ? -67.26748 -116.55720 1.48950   1.000 55.79463  ? 49  PHE A CB  1 
ATOM   106  C  CG  . PHE A 1 50  ? -67.33883 -117.93057 2.08941   1.000 56.21014  ? 49  PHE A CG  1 
ATOM   107  C  CD1 . PHE A 1 50  ? -66.20983 -118.74243 2.13842   1.000 56.29503  ? 49  PHE A CD1 1 
ATOM   108  C  CD2 . PHE A 1 50  ? -68.54481 -118.42725 2.56463   1.000 56.49792  ? 49  PHE A CD2 1 
ATOM   109  C  CE1 . PHE A 1 50  ? -66.27820 -120.02293 2.67504   1.000 57.32936  ? 49  PHE A CE1 1 
ATOM   110  C  CE2 . PHE A 1 50  ? -68.62621 -119.70389 3.09921   1.000 56.87570  ? 49  PHE A CE2 1 
ATOM   111  C  CZ  . PHE A 1 50  ? -67.49226 -120.50479 3.15815   1.000 56.96612  ? 49  PHE A CZ  1 
ATOM   112  N  N   . GLY A 1 51  ? -66.60237 -113.16187 2.03182   1.000 55.94785  ? 50  GLY A N   1 
ATOM   113  C  CA  . GLY A 1 51  ? -66.88798 -111.95788 1.29037   1.000 55.46405  ? 50  GLY A CA  1 
ATOM   114  C  C   . GLY A 1 51  ? -68.38484 -111.75743 1.18417   1.000 55.37643  ? 50  GLY A C   1 
ATOM   115  O  O   . GLY A 1 51  ? -69.17974 -112.34343 1.92311   1.000 55.81734  ? 50  GLY A O   1 
ATOM   116  N  N   . SER A 1 52  ? -68.77677 -110.91833 0.23645   1.000 39.51641  ? 51  SER A N   1 
ATOM   117  C  CA  . SER A 1 52  ? -70.19898 -110.65835 0.05272   1.000 41.71109  ? 51  SER A CA  1 
ATOM   118  C  C   . SER A 1 52  ? -70.72561 -111.73576 -0.88664  1.000 40.92184  ? 51  SER A C   1 
ATOM   119  O  O   . SER A 1 52  ? -70.89010 -111.53637 -2.09366  1.000 39.96103  ? 51  SER A O   1 
ATOM   120  C  CB  . SER A 1 52  ? -70.42863 -109.24685 -0.46739  1.000 37.22121  ? 51  SER A CB  1 
ATOM   121  O  OG  . SER A 1 52  ? -69.71910 -108.32143 0.33418   1.000 42.19426  ? 51  SER A OG  1 
ATOM   122  N  N   . VAL A 1 53  ? -70.98069 -112.90892 -0.30394  1.000 38.86382  ? 52  VAL A N   1 
ATOM   123  C  CA  . VAL A 1 53  ? -71.39765 -114.09659 -1.04035  1.000 40.90677  ? 52  VAL A CA  1 
ATOM   124  C  C   . VAL A 1 53  ? -72.76364 -114.51422 -0.52517  1.000 40.82677  ? 52  VAL A C   1 
ATOM   125  O  O   . VAL A 1 53  ? -72.92769 -114.75182 0.67683   1.000 44.05019  ? 52  VAL A O   1 
ATOM   126  C  CB  . VAL A 1 53  ? -70.38877 -115.24535 -0.89131  1.000 37.39260  ? 52  VAL A CB  1 
ATOM   127  C  CG1 . VAL A 1 53  ? -70.88738 -116.46991 -1.64188  1.000 40.24927  ? 52  VAL A CG1 1 
ATOM   128  C  CG2 . VAL A 1 53  ? -69.00457 -114.81054 -1.37830  1.000 35.73370  ? 52  VAL A CG2 1 
ATOM   129  N  N   . TYR A 1 54  ? -73.73506 -114.62203 -1.43457  1.000 37.69911  ? 53  TYR A N   1 
ATOM   130  C  CA  . TYR A 1 54  ? -75.11679 -114.92306 -1.09484  1.000 39.18367  ? 53  TYR A CA  1 
ATOM   131  C  C   . TYR A 1 54  ? -75.54485 -116.21455 -1.76821  1.000 45.46284  ? 53  TYR A C   1 
ATOM   132  O  O   . TYR A 1 54  ? -75.08062 -116.54430 -2.86429  1.000 40.93409  ? 53  TYR A O   1 
ATOM   133  C  CB  . TYR A 1 54  ? -76.06679 -113.80645 -1.54006  1.000 42.29007  ? 53  TYR A CB  1 
ATOM   134  C  CG  . TYR A 1 54  ? -75.78074 -112.46120 -0.91854  1.000 46.40485  ? 53  TYR A CG  1 
ATOM   135  C  CD1 . TYR A 1 54  ? -74.77345 -111.64699 -1.41521  1.000 38.47426  ? 53  TYR A CD1 1 
ATOM   136  C  CD2 . TYR A 1 54  ? -76.52679 -112.00046 0.16627   1.000 46.29104  ? 53  TYR A CD2 1 
ATOM   137  C  CE1 . TYR A 1 54  ? -74.50567 -110.41873 -0.85201  1.000 41.35993  ? 53  TYR A CE1 1 
ATOM   138  C  CE2 . TYR A 1 54  ? -76.26732 -110.76524 0.73423   1.000 43.68169  ? 53  TYR A CE2 1 
ATOM   139  C  CZ  . TYR A 1 54  ? -75.26260 -109.97203 0.21639   1.000 40.17525  ? 53  TYR A CZ  1 
ATOM   140  O  OH  . TYR A 1 54  ? -74.98948 -108.74175 0.77857   1.000 35.94108  ? 53  TYR A OH  1 
ATOM   141  N  N   . SER A 1 55  ? -76.45373 -116.93358 -1.11459  1.000 40.41721  ? 54  SER A N   1 
ATOM   142  C  CA  . SER A 1 55  ? -77.03398 -118.11275 -1.73076  1.000 43.86146  ? 54  SER A CA  1 
ATOM   143  C  C   . SER A 1 55  ? -78.00035 -117.68672 -2.82782  1.000 54.86991  ? 54  SER A C   1 
ATOM   144  O  O   . SER A 1 55  ? -78.65390 -116.63983 -2.73963  1.000 45.06961  ? 54  SER A O   1 
ATOM   145  C  CB  . SER A 1 55  ? -77.75268 -118.96379 -0.68333  1.000 52.01167  ? 54  SER A CB  1 
ATOM   146  O  OG  . SER A 1 55  ? -78.44817 -120.03708 -1.29363  1.000 56.62325  ? 54  SER A OG  1 
ATOM   147  N  N   . GLY A 1 56  ? -78.07997 -118.50304 -3.87878  1.000 43.95818  ? 55  GLY A N   1 
ATOM   148  C  CA  . GLY A 1 56  ? -78.94168 -118.18579 -4.99595  1.000 45.99288  ? 55  GLY A CA  1 
ATOM   149  C  C   . GLY A 1 56  ? -79.39466 -119.43875 -5.70980  1.000 48.65922  ? 55  GLY A C   1 
ATOM   150  O  O   . GLY A 1 56  ? -78.91471 -120.54324 -5.44943  1.000 50.16051  ? 55  GLY A O   1 
ATOM   151  N  N   . ILE A 1 57  ? -80.33730 -119.24341 -6.62617  1.000 48.31839  ? 56  ILE A N   1 
ATOM   152  C  CA  . ILE A 1 57  ? -80.85879 -120.31326 -7.46473  1.000 44.13633  ? 56  ILE A CA  1 
ATOM   153  C  C   . ILE A 1 57  ? -81.03536 -119.75591 -8.86368  1.000 54.07237  ? 56  ILE A C   1 
ATOM   154  O  O   . ILE A 1 57  ? -81.69159 -118.72530 -9.04683  1.000 54.18064  ? 56  ILE A O   1 
ATOM   155  C  CB  . ILE A 1 57  ? -82.19385 -120.86830 -6.92379  1.000 53.63386  ? 56  ILE A CB  1 
ATOM   156  C  CG1 . ILE A 1 57  ? -81.95177 -121.73135 -5.68208  1.000 53.07399  ? 56  ILE A CG1 1 
ATOM   157  C  CG2 . ILE A 1 57  ? -82.93509 -121.63898 -8.00344  1.000 60.21572  ? 56  ILE A CG2 1 
ATOM   158  N  N   . ARG A 1 58  ? -80.43627 -120.41583 -9.84831  1.000 50.15707  ? 57  ARG A N   1 
ATOM   159  C  CA  . ARG A 1 58  ? -80.66140 -120.02165 -11.22952 1.000 55.44021  ? 57  ARG A CA  1 
ATOM   160  C  C   . ARG A 1 58  ? -82.09454 -120.36744 -11.61460 1.000 63.28469  ? 57  ARG A C   1 
ATOM   161  O  O   . ARG A 1 58  ? -82.48529 -121.53809 -11.58488 1.000 65.32244  ? 57  ARG A O   1 
ATOM   162  C  CB  . ARG A 1 58  ? -79.66510 -120.71079 -12.15364 1.000 53.40418  ? 57  ARG A CB  1 
ATOM   163  C  CG  . ARG A 1 58  ? -79.75843 -120.24025 -13.59321 1.000 61.81606  ? 57  ARG A CG  1 
ATOM   164  C  CD  . ARG A 1 58  ? -78.47908 -120.54790 -14.34299 1.000 56.25364  ? 57  ARG A CD  1 
ATOM   165  N  NE  . ARG A 1 58  ? -78.22965 -121.98106 -14.43616 1.000 60.84677  ? 57  ARG A NE  1 
ATOM   166  C  CZ  . ARG A 1 58  ? -77.10180 -122.51461 -14.88667 1.000 57.26296  ? 57  ARG A CZ  1 
ATOM   167  N  NH1 . ARG A 1 58  ? -76.07462 -121.76046 -15.24325 1.000 54.00180  ? 57  ARG A NH1 1 
ATOM   168  N  NH2 . ARG A 1 58  ? -77.00214 -123.83651 -14.98085 1.000 58.03522  ? 57  ARG A NH2 1 
ATOM   169  N  N   . VAL A 1 59  ? -82.88173 -119.34636 -11.96065 1.000 66.03816  ? 58  VAL A N   1 
ATOM   170  C  CA  . VAL A 1 59  ? -84.30517 -119.56009 -12.20837 1.000 71.01739  ? 58  VAL A CA  1 
ATOM   171  C  C   . VAL A 1 59  ? -84.51138 -120.47242 -13.41319 1.000 77.60315  ? 58  VAL A C   1 
ATOM   172  O  O   . VAL A 1 59  ? -85.43588 -121.29462 -13.43855 1.000 75.66684  ? 58  VAL A O   1 
ATOM   173  C  CB  . VAL A 1 59  ? -85.02211 -118.20872 -12.38731 1.000 67.96461  ? 58  VAL A CB  1 
ATOM   174  C  CG2 . VAL A 1 59  ? -85.01466 -117.43037 -11.08149 1.000 64.64788  ? 58  VAL A CG2 1 
ATOM   175  N  N   . SER A 1 60  ? -83.64134 -120.36240 -14.41870 1.000 75.70793  ? 59  SER A N   1 
ATOM   176  C  CA  . SER A 1 60  ? -83.84879 -121.09640 -15.66080 1.000 82.72286  ? 59  SER A CA  1 
ATOM   177  C  C   . SER A 1 60  ? -83.77505 -122.60784 -15.48156 1.000 82.50371  ? 59  SER A C   1 
ATOM   178  O  O   . SER A 1 60  ? -84.25603 -123.33936 -16.35338 1.000 85.26743  ? 59  SER A O   1 
ATOM   179  C  CB  . SER A 1 60  ? -82.82887 -120.65507 -16.70995 1.000 84.35540  ? 59  SER A CB  1 
ATOM   180  O  OG  . SER A 1 60  ? -81.50553 -120.88286 -16.26018 1.000 80.38224  ? 59  SER A OG  1 
ATOM   181  N  N   . ASP A 1 61  ? -83.19335 -123.09938 -14.38535 1.000 75.87265  ? 60  ASP A N   1 
ATOM   182  C  CA  . ASP A 1 61  ? -83.07293 -124.54407 -14.21560 1.000 72.18341  ? 60  ASP A CA  1 
ATOM   183  C  C   . ASP A 1 61  ? -82.98959 -124.96401 -12.75088 1.000 66.94901  ? 60  ASP A C   1 
ATOM   184  O  O   . ASP A 1 61  ? -82.69008 -126.12526 -12.45527 1.000 68.24783  ? 60  ASP A O   1 
ATOM   185  C  CB  . ASP A 1 61  ? -81.85334 -125.06445 -14.98779 1.000 73.05133  ? 60  ASP A CB  1 
ATOM   186  C  CG  . ASP A 1 61  ? -80.52776 -124.69452 -14.32819 1.000 71.86584  ? 60  ASP A CG  1 
ATOM   187  O  OD1 . ASP A 1 61  ? -80.45143 -123.64160 -13.65676 1.000 63.94836  ? 60  ASP A OD1 1 
ATOM   188  O  OD2 . ASP A 1 61  ? -79.55503 -125.46199 -14.49239 1.000 64.94940  ? 60  ASP A OD2 1 
ATOM   189  N  N   . ASN A 1 62  ? -83.25523 -124.03285 -11.83244 1.000 65.99956  ? 61  ASN A N   1 
ATOM   190  C  CA  . ASN A 1 62  ? -83.20557 -124.26555 -10.38733 1.000 68.57862  ? 61  ASN A CA  1 
ATOM   191  C  C   . ASN A 1 62  ? -81.82765 -124.72573 -9.89883  1.000 64.97368  ? 61  ASN A C   1 
ATOM   192  O  O   . ASN A 1 62  ? -81.71180 -125.29246 -8.80537  1.000 64.04304  ? 61  ASN A O   1 
ATOM   193  C  CB  . ASN A 1 62  ? -84.29031 -125.25320 -9.94395  1.000 67.98177  ? 61  ASN A CB  1 
ATOM   194  C  CG  . ASN A 1 62  ? -85.66146 -124.60349 -9.84116  1.000 68.86023  ? 61  ASN A CG  1 
ATOM   195  N  N   . LEU A 1 63  ? -80.77080 -124.46420 -10.66376 1.000 59.00587  ? 62  LEU A N   1 
ATOM   196  C  CA  . LEU A 1 63  ? -79.42195 -124.81888 -10.21340 1.000 57.33802  ? 62  LEU A CA  1 
ATOM   197  C  C   . LEU A 1 63  ? -79.01489 -123.96215 -9.01852  1.000 50.30524  ? 62  LEU A C   1 
ATOM   198  O  O   . LEU A 1 63  ? -79.18678 -122.73927 -9.04985  1.000 51.77214  ? 62  LEU A O   1 
ATOM   199  C  CB  . LEU A 1 63  ? -78.40644 -124.63794 -11.33404 1.000 54.76873  ? 62  LEU A CB  1 
ATOM   200  C  CG  . LEU A 1 63  ? -76.96163 -124.97328 -10.95221 1.000 52.46041  ? 62  LEU A CG  1 
ATOM   201  C  CD1 . LEU A 1 63  ? -76.70213 -126.47733 -11.03231 1.000 46.37262  ? 62  LEU A CD1 1 
ATOM   202  C  CD2 . LEU A 1 63  ? -75.98617 -124.20507 -11.83062 1.000 48.68390  ? 62  LEU A CD2 1 
ATOM   203  N  N   . PRO A 1 64  ? -78.48035 -124.55778 -7.95585  1.000 51.23652  ? 63  PRO A N   1 
ATOM   204  C  CA  . PRO A 1 64  ? -77.95327 -123.75642 -6.84222  1.000 47.66113  ? 63  PRO A CA  1 
ATOM   205  C  C   . PRO A 1 64  ? -76.65369 -123.05201 -7.22427  1.000 47.89844  ? 63  PRO A C   1 
ATOM   206  O  O   . PRO A 1 64  ? -75.74096 -123.66251 -7.78665  1.000 44.97794  ? 63  PRO A O   1 
ATOM   207  C  CB  . PRO A 1 64  ? -77.72813 -124.79619 -5.73727  1.000 55.07987  ? 63  PRO A CB  1 
ATOM   208  C  CG  . PRO A 1 64  ? -77.58380 -126.10336 -6.47800  1.000 53.77135  ? 63  PRO A CG  1 
ATOM   209  C  CD  . PRO A 1 64  ? -78.46685 -126.00312 -7.67228  1.000 53.29383  ? 63  PRO A CD  1 
ATOM   210  N  N   . VAL A 1 65  ? -76.56755 -121.75837 -6.89318  1.000 42.78043  ? 64  VAL A N   1 
ATOM   211  C  CA  . VAL A 1 65  ? -75.39620 -120.94374 -7.19081  1.000 40.20999  ? 64  VAL A CA  1 
ATOM   212  C  C   . VAL A 1 65  ? -75.01072 -120.14251 -5.95489  1.000 42.90732  ? 64  VAL A C   1 
ATOM   213  O  O   . VAL A 1 65  ? -75.82156 -119.91294 -5.05522  1.000 43.84828  ? 64  VAL A O   1 
ATOM   214  C  CB  . VAL A 1 65  ? -75.63577 -119.97748 -8.36822  1.000 42.87810  ? 64  VAL A CB  1 
ATOM   215  C  CG1 . VAL A 1 65  ? -75.97047 -120.73511 -9.65878  1.000 37.63284  ? 64  VAL A CG1 1 
ATOM   216  C  CG2 . VAL A 1 65  ? -76.73731 -118.97861 -8.00519  1.000 40.28749  ? 64  VAL A CG2 1 
ATOM   217  N  N   . ALA A 1 66  ? -73.75801 -119.69210 -5.93462  1.000 36.61856  ? 65  ALA A N   1 
ATOM   218  C  CA  . ALA A 1 66  ? -73.28922 -118.69621 -4.98015  1.000 35.45231  ? 65  ALA A CA  1 
ATOM   219  C  C   . ALA A 1 66  ? -73.05706 -117.40002 -5.73911  1.000 39.03360  ? 65  ALA A C   1 
ATOM   220  O  O   . ALA A 1 66  ? -72.47935 -117.41308 -6.83286  1.000 37.63232  ? 65  ALA A O   1 
ATOM   221  C  CB  . ALA A 1 66  ? -72.00601 -119.14648 -4.27361  1.000 35.82030  ? 65  ALA A CB  1 
ATOM   222  N  N   . ILE A 1 67  ? -73.51242 -116.29026 -5.17021  1.000 34.59312  ? 66  ILE A N   1 
ATOM   223  C  CA  . ILE A 1 67  ? -73.48808 -114.99532 -5.83837  1.000 36.89741  ? 66  ILE A CA  1 
ATOM   224  C  C   . ILE A 1 67  ? -72.54534 -114.08793 -5.05602  1.000 37.29928  ? 66  ILE A C   1 
ATOM   225  O  O   . ILE A 1 67  ? -72.85550 -113.67399 -3.93099  1.000 39.49682  ? 66  ILE A O   1 
ATOM   226  C  CB  . ILE A 1 67  ? -74.89872 -114.39893 -5.95015  1.000 41.44921  ? 66  ILE A CB  1 
ATOM   227  C  CG1 . ILE A 1 67  ? -75.83237 -115.40053 -6.64091  1.000 38.86732  ? 66  ILE A CG1 1 
ATOM   228  C  CG2 . ILE A 1 67  ? -74.86599 -113.08799 -6.71649  1.000 38.87234  ? 66  ILE A CG2 1 
ATOM   229  C  CD1 . ILE A 1 67  ? -77.28940 -114.96155 -6.70500  1.000 49.23244  ? 66  ILE A CD1 1 
ATOM   230  N  N   . LYS A 1 68  ? -71.39149 -113.77581 -5.64218  1.000 35.41165  ? 67  LYS A N   1 
ATOM   231  C  CA  . LYS A 1 68  ? -70.34954 -113.00471 -4.97069  1.000 34.62147  ? 67  LYS A CA  1 
ATOM   232  C  C   . LYS A 1 68  ? -70.27009 -111.60288 -5.56322  1.000 37.30998  ? 67  LYS A C   1 
ATOM   233  O  O   . LYS A 1 68  ? -70.19204 -111.44435 -6.78455  1.000 35.82233  ? 67  LYS A O   1 
ATOM   234  C  CB  . LYS A 1 68  ? -68.98891 -113.69070 -5.08427  1.000 35.57037  ? 67  LYS A CB  1 
ATOM   235  C  CG  . LYS A 1 68  ? -67.83365 -112.86894 -4.49666  1.000 35.09369  ? 67  LYS A CG  1 
ATOM   236  C  CD  . LYS A 1 68  ? -66.53578 -113.65647 -4.53093  1.000 37.81581  ? 67  LYS A CD  1 
ATOM   237  C  CE  . LYS A 1 68  ? -65.42021 -112.97268 -3.73307  1.000 44.85130  ? 67  LYS A CE  1 
ATOM   238  N  NZ  . LYS A 1 68  ? -64.13289 -113.73973 -3.83432  1.000 38.44761  ? 67  LYS A NZ  1 
ATOM   239  N  N   . HIS A 1 69  ? -70.25800 -110.60001 -4.68891  1.000 36.06287  ? 68  HIS A N   1 
ATOM   240  C  CA  . HIS A 1 69  ? -70.21002 -109.19687 -5.06469  1.000 35.28121  ? 68  HIS A CA  1 
ATOM   241  C  C   . HIS A 1 69  ? -68.86308 -108.61978 -4.66356  1.000 34.82961  ? 68  HIS A C   1 
ATOM   242  O  O   . HIS A 1 69  ? -68.40698 -108.82455 -3.53457  1.000 39.63508  ? 68  HIS A O   1 
ATOM   243  C  CB  . HIS A 1 69  ? -71.33640 -108.40216 -4.38145  1.000 35.99699  ? 68  HIS A CB  1 
ATOM   244  C  CG  . HIS A 1 69  ? -72.70801 -108.89829 -4.70159  1.000 36.23761  ? 68  HIS A CG  1 
ATOM   245  N  ND1 . HIS A 1 69  ? -73.56924 -108.21594 -5.53361  1.000 38.54239  ? 68  HIS A ND1 1 
ATOM   246  C  CD2 . HIS A 1 69  ? -73.36845 -110.01246 -4.30595  1.000 36.00150  ? 68  HIS A CD2 1 
ATOM   247  C  CE1 . HIS A 1 69  ? -74.70706 -108.88386 -5.62856  1.000 41.53815  ? 68  HIS A CE1 1 
ATOM   248  N  NE2 . HIS A 1 69  ? -74.60635 -109.98351 -4.90139  1.000 40.96409  ? 68  HIS A NE2 1 
ATOM   249  N  N   . VAL A 1 70  ? -68.23721 -107.88273 -5.57671  1.000 35.21156  ? 69  VAL A N   1 
ATOM   250  C  CA  . VAL A 1 70  ? -66.97094 -107.22422 -5.30260  1.000 37.44915  ? 69  VAL A CA  1 
ATOM   251  C  C   . VAL A 1 70  ? -67.10508 -105.76493 -5.70402  1.000 37.22062  ? 69  VAL A C   1 
ATOM   252  O  O   . VAL A 1 70  ? -67.61659 -105.45399 -6.78606  1.000 40.99056  ? 69  VAL A O   1 
ATOM   253  C  CB  . VAL A 1 70  ? -65.80318 -107.90751 -6.03952  1.000 48.46685  ? 69  VAL A CB  1 
ATOM   254  C  CG1 . VAL A 1 70  ? -64.53475 -107.11747 -5.85491  1.000 53.48612  ? 69  VAL A CG1 1 
ATOM   255  C  CG2 . VAL A 1 70  ? -65.61797 -109.31447 -5.49330  1.000 40.55708  ? 69  VAL A CG2 1 
ATOM   256  N  N   . GLU A 1 71  ? -66.66295 -104.87631 -4.82659  1.000 43.57392  ? 70  GLU A N   1 
ATOM   257  C  CA  . GLU A 1 71  ? -66.84672 -103.44262 -4.99834  1.000 49.84057  ? 70  GLU A CA  1 
ATOM   258  C  C   . GLU A 1 71  ? -65.71139 -102.88209 -5.84500  1.000 51.12262  ? 70  GLU A C   1 
ATOM   259  O  O   . GLU A 1 71  ? -64.54020 -103.09081 -5.51874  1.000 47.11649  ? 70  GLU A O   1 
ATOM   260  C  CB  . GLU A 1 71  ? -66.88574 -102.77346 -3.62181  1.000 55.57863  ? 70  GLU A CB  1 
ATOM   261  C  CG  . GLU A 1 71  ? -67.51071 -101.39413 -3.57270  1.000 59.52161  ? 70  GLU A CG  1 
ATOM   262  C  CD  . GLU A 1 71  ? -67.73212 -100.92071 -2.14258  1.000 62.54493  ? 70  GLU A CD  1 
ATOM   263  O  OE1 . GLU A 1 71  ? -68.18423 -101.73466 -1.30099  1.000 57.98893  ? 70  GLU A OE1 1 
ATOM   264  O  OE2 . GLU A 1 71  ? -67.44377 -99.73964  -1.85597  1.000 68.10726  ? 70  GLU A OE2 1 
ATOM   265  N  N   . LYS A 1 72  ? -66.06130 -102.17105 -6.92940  1.000 51.62427  ? 71  LYS A N   1 
ATOM   266  C  CA  . LYS A 1 72  ? -65.04615 -101.61759 -7.82816  1.000 55.32746  ? 71  LYS A CA  1 
ATOM   267  C  C   . LYS A 1 72  ? -64.02973 -100.76533 -7.07900  1.000 60.22732  ? 71  LYS A C   1 
ATOM   268  O  O   . LYS A 1 72  ? -62.82144 -100.86924 -7.32609  1.000 60.29002  ? 71  LYS A O   1 
ATOM   269  C  CB  . LYS A 1 72  ? -65.69390 -100.77832 -8.93460  1.000 55.05950  ? 71  LYS A CB  1 
ATOM   270  C  CG  . LYS A 1 72  ? -66.59153 -101.53646 -9.88954  1.000 51.63777  ? 71  LYS A CG  1 
ATOM   271  C  CD  . LYS A 1 72  ? -67.09158 -100.61471 -11.00396 1.000 52.42276  ? 71  LYS A CD  1 
ATOM   272  C  CE  . LYS A 1 72  ? -67.85555 -101.38459 -12.05841 1.000 51.37060  ? 71  LYS A CE  1 
ATOM   273  N  NZ  . LYS A 1 72  ? -68.49332 -100.48315 -13.06220 1.000 52.72962  ? 71  LYS A NZ  1 
ATOM   274  N  N   . ASP A 1 73  ? -64.50584 -99.90612  -6.16875  1.000 65.20549  ? 72  ASP A N   1 
ATOM   275  C  CA  . ASP A 1 73  ? -63.62330 -99.04598  -5.38425  1.000 70.79198  ? 72  ASP A CA  1 
ATOM   276  C  C   . ASP A 1 73  ? -62.58279 -99.83529  -4.60663  1.000 68.09626  ? 72  ASP A C   1 
ATOM   277  O  O   . ASP A 1 73  ? -61.51646 -99.29570  -4.29737  1.000 66.99991  ? 72  ASP A O   1 
ATOM   278  C  CB  . ASP A 1 73  ? -64.43489 -98.19474  -4.40101  1.000 71.76804  ? 72  ASP A CB  1 
ATOM   279  C  CG  . ASP A 1 73  ? -65.19807 -97.07061  -5.07923  1.000 81.13839  ? 72  ASP A CG  1 
ATOM   280  O  OD1 . ASP A 1 73  ? -65.00388 -96.85449  -6.29564  1.000 81.30432  ? 72  ASP A OD1 1 
ATOM   281  O  OD2 . ASP A 1 73  ? -65.99589 -96.40137  -4.38660  1.000 81.16459  ? 72  ASP A OD2 1 
ATOM   282  N  N   . ARG A 1 74  ? -62.86521 -101.09351 -4.28369  1.000 63.65603  ? 73  ARG A N   1 
ATOM   283  C  CA  . ARG A 1 74  ? -61.99178 -101.89348 -3.44014  1.000 67.60261  ? 73  ARG A CA  1 
ATOM   284  C  C   . ARG A 1 74  ? -61.04926 -102.79576 -4.22388  1.000 61.82373  ? 73  ARG A C   1 
ATOM   285  O  O   . ARG A 1 74  ? -60.29915 -103.55674 -3.60925  1.000 68.68137  ? 73  ARG A O   1 
ATOM   286  C  CB  . ARG A 1 74  ? -62.82869 -102.74745 -2.47991  1.000 60.48926  ? 73  ARG A CB  1 
ATOM   287  C  CG  . ARG A 1 74  ? -63.67889 -101.94708 -1.50961  1.000 63.10019  ? 73  ARG A CG  1 
ATOM   288  C  CD  . ARG A 1 74  ? -64.20534 -102.83402 -0.39582  1.000 64.04635  ? 73  ARG A CD  1 
ATOM   289  N  NE  . ARG A 1 74  ? -64.76040 -102.05127 0.70111   1.000 71.33408  ? 73  ARG A NE  1 
ATOM   290  C  CZ  . ARG A 1 74  ? -66.01476 -102.13247 1.12225   1.000 68.88137  ? 73  ARG A CZ  1 
ATOM   291  N  NH1 . ARG A 1 74  ? -66.87340 -102.98014 0.57581   1.000 63.59558  ? 73  ARG A NH1 1 
ATOM   292  N  NH2 . ARG A 1 74  ? -66.41471 -101.35310 2.12646   1.000 60.57630  ? 73  ARG A NH2 1 
ATOM   293  N  N   . ILE A 1 75  ? -61.05761 -102.73157 -5.55031  1.000 65.22171  ? 74  ILE A N   1 
ATOM   294  C  CA  . ILE A 1 75  ? -60.30359 -103.67139 -6.37359  1.000 61.22868  ? 74  ILE A CA  1 
ATOM   295  C  C   . ILE A 1 75  ? -58.92956 -103.08909 -6.66766  1.000 70.05219  ? 74  ILE A C   1 
ATOM   296  O  O   . ILE A 1 75  ? -58.81487 -102.01810 -7.27201  1.000 72.64710  ? 74  ILE A O   1 
ATOM   297  C  CB  . ILE A 1 75  ? -61.05510 -103.99878 -7.67044  1.000 62.74767  ? 74  ILE A CB  1 
ATOM   298  C  CG1 . ILE A 1 75  ? -62.25447 -104.89359 -7.35716  1.000 61.53328  ? 74  ILE A CG1 1 
ATOM   299  C  CG2 . ILE A 1 75  ? -60.11953 -104.66321 -8.69383  1.000 59.72548  ? 74  ILE A CG2 1 
ATOM   300  C  CD1 . ILE A 1 75  ? -63.31418 -104.85542 -8.41405  1.000 58.72837  ? 74  ILE A CD1 1 
ATOM   301  N  N   . SER A 1 76  ? -57.88611 -103.80559 -6.25322  1.000 75.53138  ? 75  SER A N   1 
ATOM   302  C  CA  . SER A 1 76  ? -56.51730 -103.34334 -6.43951  1.000 81.54882  ? 75  SER A CA  1 
ATOM   303  C  C   . SER A 1 76  ? -55.93439 -103.73802 -7.78853  1.000 72.44234  ? 75  SER A C   1 
ATOM   304  O  O   . SER A 1 76  ? -55.11574 -102.99267 -8.33851  1.000 75.69581  ? 75  SER A O   1 
ATOM   305  C  CB  . SER A 1 76  ? -55.62062 -103.88901 -5.32209  1.000 81.20869  ? 75  SER A CB  1 
ATOM   306  N  N   . ASP A 1 77  ? -56.33236 -104.88439 -8.33909  1.000 62.02480  ? 76  ASP A N   1 
ATOM   307  C  CA  . ASP A 1 77  ? -55.68928 -105.43642 -9.52516  1.000 63.42664  ? 76  ASP A CA  1 
ATOM   308  C  C   . ASP A 1 77  ? -56.72746 -105.69067 -10.60777 1.000 59.37105  ? 76  ASP A C   1 
ATOM   309  O  O   . ASP A 1 77  ? -57.72199 -106.38804 -10.37516 1.000 56.85437  ? 76  ASP A O   1 
ATOM   310  C  CB  . ASP A 1 77  ? -54.93294 -106.73232 -9.19098  1.000 67.51897  ? 76  ASP A CB  1 
ATOM   311  C  CG  . ASP A 1 77  ? -53.83157 -107.03716 -10.19363 1.000 64.31283  ? 76  ASP A CG  1 
ATOM   312  N  N   . TRP A 1 78  ? -56.48345 -105.13375 -11.78839 1.000 62.43256  ? 77  TRP A N   1 
ATOM   313  C  CA  . TRP A 1 78  ? -57.38482 -105.22380 -12.92312 1.000 59.05932  ? 77  TRP A CA  1 
ATOM   314  C  C   . TRP A 1 78  ? -56.71774 -105.98821 -14.05426 1.000 59.27971  ? 77  TRP A C   1 
ATOM   315  O  O   . TRP A 1 78  ? -55.49003 -106.06060 -14.14447 1.000 67.71447  ? 77  TRP A O   1 
ATOM   316  C  CB  . TRP A 1 78  ? -57.80249 -103.82738 -13.41272 1.000 60.86507  ? 77  TRP A CB  1 
ATOM   317  C  CG  . TRP A 1 78  ? -58.63176 -103.09659 -12.41783 1.000 62.05220  ? 77  TRP A CG  1 
ATOM   318  C  CD1 . TRP A 1 78  ? -58.18668 -102.41424 -11.32329 1.000 59.77876  ? 77  TRP A CD1 1 
ATOM   319  C  CD2 . TRP A 1 78  ? -60.05858 -102.98547 -12.40985 1.000 52.79239  ? 77  TRP A CD2 1 
ATOM   320  N  NE1 . TRP A 1 78  ? -59.24776 -101.88354 -10.63546 1.000 60.57992  ? 77  TRP A NE1 1 
ATOM   321  C  CE2 . TRP A 1 78  ? -60.40978 -102.22082 -11.27912 1.000 61.59412  ? 77  TRP A CE2 1 
ATOM   322  C  CE3 . TRP A 1 78  ? -61.07254 -103.46213 -13.24607 1.000 56.32707  ? 77  TRP A CE3 1 
ATOM   323  C  CZ2 . TRP A 1 78  ? -61.73618 -101.91915 -10.96088 1.000 59.88538  ? 77  TRP A CZ2 1 
ATOM   324  C  CZ3 . TRP A 1 78  ? -62.38769 -103.16039 -12.93420 1.000 61.34855  ? 77  TRP A CZ3 1 
ATOM   325  C  CH2 . TRP A 1 78  ? -62.70806 -102.39660 -11.79790 1.000 59.85723  ? 77  TRP A CH2 1 
ATOM   326  N  N   . GLY A 1 79  ? -57.54920 -106.55117 -14.92798 1.000 58.84660  ? 78  GLY A N   1 
ATOM   327  C  CA  . GLY A 1 79  ? -57.07324 -107.27592 -16.08502 1.000 53.73260  ? 78  GLY A CA  1 
ATOM   328  C  C   . GLY A 1 79  ? -58.02621 -107.09302 -17.24546 1.000 64.61955  ? 78  GLY A C   1 
ATOM   329  O  O   . GLY A 1 79  ? -59.04050 -106.39809 -17.14360 1.000 64.82849  ? 78  GLY A O   1 
ATOM   330  N  N   . GLU A 1 80  ? -57.68389 -107.72626 -18.36477 1.000 64.49734  ? 79  GLU A N   1 
ATOM   331  C  CA  . GLU A 1 80  ? -58.49527 -107.68111 -19.57226 1.000 70.50072  ? 79  GLU A CA  1 
ATOM   332  C  C   . GLU A 1 80  ? -58.98667 -109.08359 -19.89580 1.000 70.26532  ? 79  GLU A C   1 
ATOM   333  O  O   . GLU A 1 80  ? -58.21576 -110.04914 -19.83124 1.000 66.49744  ? 79  GLU A O   1 
ATOM   334  C  CB  . GLU A 1 80  ? -57.70590 -107.10029 -20.75287 1.000 73.06141  ? 79  GLU A CB  1 
ATOM   335  N  N   . LEU A 1 81  ? -60.27320 -109.19236 -20.22409 1.000 73.40662  ? 80  LEU A N   1 
ATOM   336  C  CA  . LEU A 1 81  ? -60.84538 -110.45032 -20.66418 1.000 74.09422  ? 80  LEU A CA  1 
ATOM   337  C  C   . LEU A 1 81  ? -60.26027 -110.82237 -22.02493 1.000 87.09986  ? 80  LEU A C   1 
ATOM   338  O  O   . LEU A 1 81  ? -59.62506 -109.99449 -22.68436 1.000 82.18961  ? 80  LEU A O   1 
ATOM   339  C  CB  . LEU A 1 81  ? -62.37012 -110.34211 -20.72266 1.000 77.82355  ? 80  LEU A CB  1 
ATOM   340  C  CG  . LEU A 1 81  ? -63.12191 -110.55843 -19.40683 1.000 65.83998  ? 80  LEU A CG  1 
ATOM   341  N  N   . PRO A 1 82  ? -60.44876 -112.08281 -22.47289 1.000 91.71076  ? 81  PRO A N   1 
ATOM   342  C  CA  . PRO A 1 82  ? -59.95670 -112.47597 -23.80154 1.000 97.87842  ? 81  PRO A CA  1 
ATOM   343  C  C   . PRO A 1 82  ? -60.37298 -111.53407 -24.92431 1.000 97.55039  ? 81  PRO A C   1 
ATOM   344  O  O   . PRO A 1 82  ? -59.72266 -111.50049 -25.97268 1.000 103.46388 ? 81  PRO A O   1 
ATOM   345  C  CB  . PRO A 1 82  ? -60.56393 -113.87112 -23.98872 1.000 97.26039  ? 81  PRO A CB  1 
ATOM   346  C  CG  . PRO A 1 82  ? -60.62135 -114.42028 -22.61507 1.000 85.89322  ? 81  PRO A CG  1 
ATOM   347  C  CD  . PRO A 1 82  ? -60.94534 -113.24848 -21.71485 1.000 94.03654  ? 81  PRO A CD  1 
ATOM   348  N  N   . ASN A 1 83  ? -61.43699 -110.75474 -24.71718 1.000 93.33087  ? 82  ASN A N   1 
ATOM   349  C  CA  . ASN A 1 83  ? -61.91938 -109.79944 -25.70888 1.000 91.20592  ? 82  ASN A CA  1 
ATOM   350  C  C   . ASN A 1 83  ? -61.62139 -108.35018 -25.32579 1.000 88.87707  ? 82  ASN A C   1 
ATOM   351  O  O   . ASN A 1 83  ? -62.24439 -107.43059 -25.86521 1.000 88.36640  ? 82  ASN A O   1 
ATOM   352  C  CB  . ASN A 1 83  ? -63.41867 -109.99320 -25.93923 1.000 91.40970  ? 82  ASN A CB  1 
ATOM   353  C  CG  . ASN A 1 83  ? -64.22029 -109.91860 -24.65350 1.000 91.22247  ? 82  ASN A CG  1 
ATOM   354  O  OD1 . ASN A 1 83  ? -64.81912 -108.88833 -24.34275 1.000 90.04075  ? 82  ASN A OD1 1 
ATOM   355  N  ND2 . ASN A 1 83  ? -64.23245 -111.01326 -23.89548 1.000 89.92362  ? 82  ASN A ND2 1 
ATOM   356  N  N   . GLY A 1 84  ? -60.68958 -108.12714 -24.39672 1.000 92.77119  ? 83  GLY A N   1 
ATOM   357  C  CA  . GLY A 1 84  ? -60.22036 -106.79594 -24.07341 1.000 89.18503  ? 83  GLY A CA  1 
ATOM   358  C  C   . GLY A 1 84  ? -61.00900 -106.04547 -23.01814 1.000 89.18158  ? 83  GLY A C   1 
ATOM   359  O  O   . GLY A 1 84  ? -60.58863 -104.94900 -22.62685 1.000 95.66182  ? 83  GLY A O   1 
ATOM   360  N  N   . THR A 1 85  ? -62.13049 -106.58748 -22.54514 1.000 86.79498  ? 84  THR A N   1 
ATOM   361  C  CA  . THR A 1 85  ? -62.93867 -105.88709 -21.55195 1.000 88.08743  ? 84  THR A CA  1 
ATOM   362  C  C   . THR A 1 85  ? -62.18878 -105.76916 -20.22984 1.000 79.85451  ? 84  THR A C   1 
ATOM   363  O  O   . THR A 1 85  ? -61.55244 -106.72223 -19.77215 1.000 78.73390  ? 84  THR A O   1 
ATOM   364  C  CB  . THR A 1 85  ? -64.26477 -106.61315 -21.32212 1.000 84.18508  ? 84  THR A CB  1 
ATOM   365  O  OG1 . THR A 1 85  ? -64.87086 -106.92226 -22.58155 1.000 90.97358  ? 84  THR A OG1 1 
ATOM   366  C  CG2 . THR A 1 85  ? -65.21573 -105.74030 -20.51080 1.000 79.94485  ? 84  THR A CG2 1 
ATOM   367  N  N   . ARG A 1 86  ? -62.26855 -104.58930 -19.61503 1.000 77.76362  ? 85  ARG A N   1 
ATOM   368  C  CA  . ARG A 1 86  ? -61.57613 -104.32386 -18.35778 1.000 71.02332  ? 85  ARG A CA  1 
ATOM   369  C  C   . ARG A 1 86  ? -62.41445 -104.87444 -17.21211 1.000 71.32759  ? 85  ARG A C   1 
ATOM   370  O  O   . ARG A 1 86  ? -63.52796 -104.39757 -16.96410 1.000 70.89868  ? 85  ARG A O   1 
ATOM   371  C  CB  . ARG A 1 86  ? -61.32324 -102.82944 -18.18567 1.000 74.96729  ? 85  ARG A CB  1 
ATOM   372  C  CG  . ARG A 1 86  ? -60.61266 -102.46323 -16.88383 1.000 69.24143  ? 85  ARG A CG  1 
ATOM   373  N  N   . VAL A 1 87  ? -61.88927 -105.88632 -16.52403 1.000 64.83523  ? 86  VAL A N   1 
ATOM   374  C  CA  . VAL A 1 87  ? -62.59778 -106.53765 -15.42253 1.000 53.30401  ? 86  VAL A CA  1 
ATOM   375  C  C   . VAL A 1 87  ? -61.61410 -106.76060 -14.28130 1.000 56.54886  ? 86  VAL A C   1 
ATOM   376  O  O   . VAL A 1 87  ? -60.39239 -106.65926 -14.46741 1.000 57.58844  ? 86  VAL A O   1 
ATOM   377  C  CB  . VAL A 1 87  ? -63.23575 -107.87769 -15.86376 1.000 56.70214  ? 86  VAL A CB  1 
ATOM   378  C  CG1 . VAL A 1 87  ? -64.19222 -107.67055 -17.04367 1.000 54.77654  ? 86  VAL A CG1 1 
ATOM   379  C  CG2 . VAL A 1 87  ? -62.15911 -108.90086 -16.19436 1.000 50.27153  ? 86  VAL A CG2 1 
ATOM   380  N  N   . PRO A 1 88  ? -62.11532 -107.04903 -13.07836 1.000 49.66119  ? 87  PRO A N   1 
ATOM   381  C  CA  . PRO A 1 88  ? -61.21717 -107.44144 -11.98809 1.000 48.21238  ? 87  PRO A CA  1 
ATOM   382  C  C   . PRO A 1 88  ? -60.37985 -108.64816 -12.38353 1.000 47.26168  ? 87  PRO A C   1 
ATOM   383  O  O   . PRO A 1 88  ? -60.83175 -109.53352 -13.11573 1.000 44.29183  ? 87  PRO A O   1 
ATOM   384  C  CB  . PRO A 1 88  ? -62.17734 -107.77887 -10.84145 1.000 47.67201  ? 87  PRO A CB  1 
ATOM   385  C  CG  . PRO A 1 88  ? -63.41383 -106.99959 -11.16314 1.000 54.65168  ? 87  PRO A CG  1 
ATOM   386  C  CD  . PRO A 1 88  ? -63.51936 -107.02096 -12.63934 1.000 46.83420  ? 87  PRO A CD  1 
ATOM   387  N  N   . MET A 1 89  ? -59.13090 -108.65688 -11.90798 1.000 49.15819  ? 88  MET A N   1 
ATOM   388  C  CA  . MET A 1 89  ? -58.26064 -109.81189 -12.11200 1.000 49.15153  ? 88  MET A CA  1 
ATOM   389  C  C   . MET A 1 89  ? -58.94061 -111.10154 -11.65727 1.000 42.67162  ? 88  MET A C   1 
ATOM   390  O  O   . MET A 1 89  ? -58.81257 -112.14832 -12.30522 1.000 41.81832  ? 88  MET A O   1 
ATOM   391  C  CB  . MET A 1 89  ? -56.94820 -109.60001 -11.35610 1.000 56.46595  ? 88  MET A CB  1 
ATOM   392  C  CG  . MET A 1 89  ? -55.98087 -110.76256 -11.46288 1.000 55.42668  ? 88  MET A CG  1 
ATOM   393  S  SD  . MET A 1 89  ? -55.44054 -111.00576 -13.15499 1.000 58.84804  ? 88  MET A SD  1 
ATOM   394  C  CE  . MET A 1 89  ? -54.56422 -109.46957 -13.46674 1.000 57.22710  ? 88  MET A CE  1 
ATOM   395  N  N   . GLU A 1 90  ? -59.68332 -111.03655 -10.55012 1.000 45.06840  ? 89  GLU A N   1 
ATOM   396  C  CA  . GLU A 1 90  ? -60.38394 -112.21582 -10.05431 1.000 39.22463  ? 89  GLU A CA  1 
ATOM   397  C  C   . GLU A 1 90  ? -61.24662 -112.84880 -11.13931 1.000 38.93396  ? 89  GLU A C   1 
ATOM   398  O  O   . GLU A 1 90  ? -61.26554 -114.07659 -11.28975 1.000 40.97855  ? 89  GLU A O   1 
ATOM   399  C  CB  . GLU A 1 90  ? -61.22986 -111.84647 -8.83150  1.000 44.50413  ? 89  GLU A CB  1 
ATOM   400  C  CG  . GLU A 1 90  ? -61.92615 -113.03900 -8.20947  1.000 37.58720  ? 89  GLU A CG  1 
ATOM   401  C  CD  . GLU A 1 90  ? -62.63420 -112.70716 -6.91732  1.000 43.51707  ? 89  GLU A CD  1 
ATOM   402  O  OE1 . GLU A 1 90  ? -62.60095 -111.53012 -6.49806  1.000 40.30298  ? 89  GLU A OE1 1 
ATOM   403  O  OE2 . GLU A 1 90  ? -63.21200 -113.63236 -6.30890  1.000 42.78903  ? 89  GLU A OE2 1 
ATOM   404  N  N   . VAL A 1 91  ? -61.94204 -112.02483 -11.93252 1.000 39.61428  ? 90  VAL A N   1 
ATOM   405  C  CA  . VAL A 1 91  ? -62.78005 -112.56671 -12.99878 1.000 37.62734  ? 90  VAL A CA  1 
ATOM   406  C  C   . VAL A 1 91  ? -61.92130 -113.17430 -14.09484 1.000 37.35374  ? 90  VAL A C   1 
ATOM   407  O  O   . VAL A 1 91  ? -62.23440 -114.25345 -14.61553 1.000 38.44835  ? 90  VAL A O   1 
ATOM   408  C  CB  . VAL A 1 91  ? -63.71831 -111.48256 -13.55953 1.000 37.87575  ? 90  VAL A CB  1 
ATOM   409  C  CG1 . VAL A 1 91  ? -64.38257 -111.97524 -14.81993 1.000 40.78452  ? 90  VAL A CG1 1 
ATOM   410  C  CG2 . VAL A 1 91  ? -64.78026 -111.09876 -12.50790 1.000 39.59752  ? 90  VAL A CG2 1 
ATOM   411  N  N   . VAL A 1 92  ? -60.82998 -112.48814 -14.46671 1.000 38.09161  ? 91  VAL A N   1 
ATOM   412  C  CA  . VAL A 1 92  ? -59.89498 -113.01307 -15.46605 1.000 35.97414  ? 91  VAL A CA  1 
ATOM   413  C  C   . VAL A 1 92  ? -59.43183 -114.41219 -15.09001 1.000 39.65651  ? 91  VAL A C   1 
ATOM   414  O  O   . VAL A 1 92  ? -59.45436 -115.34134 -15.91030 1.000 37.17531  ? 91  VAL A O   1 
ATOM   415  C  CB  . VAL A 1 92  ? -58.68852 -112.06843 -15.62535 1.000 42.19858  ? 91  VAL A CB  1 
ATOM   416  C  CG1 . VAL A 1 92  ? -57.63567 -112.71443 -16.51620 1.000 40.10984  ? 91  VAL A CG1 1 
ATOM   417  C  CG2 . VAL A 1 92  ? -59.12838 -110.72498 -16.18885 1.000 44.93662  ? 91  VAL A CG2 1 
ATOM   418  N  N   . LEU A 1 93  ? -58.97274 -114.57064 -13.84628 1.000 36.65951  ? 92  LEU A N   1 
ATOM   419  C  CA  . LEU A 1 93  ? -58.42628 -115.85286 -13.40846 1.000 34.25352  ? 92  LEU A CA  1 
ATOM   420  C  C   . LEU A 1 93  ? -59.51516 -116.91014 -13.30994 1.000 38.12855  ? 92  LEU A C   1 
ATOM   421  O  O   . LEU A 1 93  ? -59.32171 -118.05259 -13.73752 1.000 38.31482  ? 92  LEU A O   1 
ATOM   422  C  CB  . LEU A 1 93  ? -57.72340 -115.68711 -12.06376 1.000 36.38944  ? 92  LEU A CB  1 
ATOM   423  C  CG  . LEU A 1 93  ? -56.63291 -114.61549 -12.01643 1.000 40.28930  ? 92  LEU A CG  1 
ATOM   424  C  CD1 . LEU A 1 93  ? -56.05010 -114.52227 -10.60521 1.000 37.31399  ? 92  LEU A CD1 1 
ATOM   425  C  CD2 . LEU A 1 93  ? -55.55338 -114.92336 -13.03304 1.000 37.48107  ? 92  LEU A CD2 1 
ATOM   426  N  N   . LEU A 1 94  ? -60.65757 -116.55715 -12.70962 1.000 38.46042  ? 93  LEU A N   1 
ATOM   427  C  CA  . LEU A 1 94  ? -61.76863 -117.50100 -12.62455 1.000 39.08301  ? 93  LEU A CA  1 
ATOM   428  C  C   . LEU A 1 94  ? -62.17434 -117.99786 -13.99985 1.000 36.34172  ? 93  LEU A C   1 
ATOM   429  O  O   . LEU A 1 94  ? -62.39601 -119.19842 -14.19456 1.000 36.34205  ? 93  LEU A O   1 
ATOM   430  C  CB  . LEU A 1 94  ? -62.96553 -116.85769 -11.92032 1.000 34.79537  ? 93  LEU A CB  1 
ATOM   431  C  CG  . LEU A 1 94  ? -62.92884 -116.92963 -10.39051 1.000 38.59016  ? 93  LEU A CG  1 
ATOM   432  C  CD1 . LEU A 1 94  ? -63.97558 -116.00043 -9.79792  1.000 33.29436  ? 93  LEU A CD1 1 
ATOM   433  C  CD2 . LEU A 1 94  ? -63.13956 -118.36491 -9.90079  1.000 35.50753  ? 93  LEU A CD2 1 
ATOM   434  N  N   . LYS A 1 95  ? -62.28308 -117.08965 -14.97235 1.000 36.42958  ? 94  LYS A N   1 
ATOM   435  C  CA  . LYS A 1 95  ? -62.66074 -117.51859 -16.31227 1.000 39.71840  ? 94  LYS A CA  1 
ATOM   436  C  C   . LYS A 1 95  ? -61.63492 -118.48498 -16.89008 1.000 42.47660  ? 94  LYS A C   1 
ATOM   437  O  O   . LYS A 1 95  ? -61.99855 -119.46048 -17.55903 1.000 37.31747  ? 94  LYS A O   1 
ATOM   438  C  CB  . LYS A 1 95  ? -62.83083 -116.30677 -17.22896 1.000 41.22748  ? 94  LYS A CB  1 
ATOM   439  C  CG  . LYS A 1 95  ? -63.28396 -116.68182 -18.60921 1.000 50.48930  ? 94  LYS A CG  1 
ATOM   440  N  N   . LYS A 1 96  ? -60.34770 -118.24634 -16.61923 1.000 37.80288  ? 95  LYS A N   1 
ATOM   441  C  CA  . LYS A 1 96  ? -59.30039 -119.11442 -17.15581 1.000 39.50677  ? 95  LYS A CA  1 
ATOM   442  C  C   . LYS A 1 96  ? -59.33864 -120.52028 -16.55650 1.000 41.38184  ? 95  LYS A C   1 
ATOM   443  O  O   . LYS A 1 96  ? -59.01945 -121.49082 -17.24950 1.000 39.30387  ? 95  LYS A O   1 
ATOM   444  C  CB  . LYS A 1 96  ? -57.92697 -118.47517 -16.93132 1.000 37.12770  ? 95  LYS A CB  1 
ATOM   445  C  CG  . LYS A 1 96  ? -57.65903 -117.28784 -17.87380 1.000 42.69293  ? 95  LYS A CG  1 
ATOM   446  C  CD  . LYS A 1 96  ? -56.38736 -116.52094 -17.51796 1.000 44.59416  ? 95  LYS A CD  1 
ATOM   447  C  CE  . LYS A 1 96  ? -55.12903 -117.31251 -17.84151 1.000 51.42318  ? 95  LYS A CE  1 
ATOM   448  N  NZ  . LYS A 1 96  ? -55.06715 -117.80212 -19.26790 1.000 54.24751  ? 95  LYS A NZ  1 
ATOM   449  N  N   . VAL A 1 97  ? -59.71688 -120.66651 -15.28341 1.000 36.66720  ? 96  VAL A N   1 
ATOM   450  C  CA  . VAL A 1 97  ? -59.73360 -121.99624 -14.67746 1.000 38.86846  ? 96  VAL A CA  1 
ATOM   451  C  C   . VAL A 1 97  ? -61.10175 -122.66591 -14.72484 1.000 42.60164  ? 96  VAL A C   1 
ATOM   452  O  O   . VAL A 1 97  ? -61.21128 -123.84814 -14.35754 1.000 39.09634  ? 96  VAL A O   1 
ATOM   453  C  CB  . VAL A 1 97  ? -59.22664 -121.94912 -13.22121 1.000 37.67093  ? 96  VAL A CB  1 
ATOM   454  C  CG1 . VAL A 1 97  ? -57.85314 -121.31855 -13.19312 1.000 38.78257  ? 96  VAL A CG1 1 
ATOM   455  C  CG2 . VAL A 1 97  ? -60.19448 -121.15970 -12.34020 1.000 35.61885  ? 96  VAL A CG2 1 
ATOM   456  N  N   . SER A 1 98  ? -62.13956 -121.97035 -15.17885 1.000 36.13124  ? 97  SER A N   1 
ATOM   457  C  CA  . SER A 1 98  ? -63.49395 -122.49254 -15.07718 1.000 39.58337  ? 97  SER A CA  1 
ATOM   458  C  C   . SER A 1 98  ? -63.93128 -123.26798 -16.31370 1.000 49.86963  ? 97  SER A C   1 
ATOM   459  O  O   . SER A 1 98  ? -65.10378 -123.65120 -16.41133 1.000 51.70138  ? 97  SER A O   1 
ATOM   460  C  CB  . SER A 1 98  ? -64.47139 -121.35433 -14.78139 1.000 45.32048  ? 97  SER A CB  1 
ATOM   461  O  OG  . SER A 1 98  ? -64.24347 -120.85233 -13.46156 1.000 36.43300  ? 97  SER A OG  1 
ATOM   462  N  N   . SER A 1 99  ? -63.02294 -123.52267 -17.24686 1.000 47.31768  ? 98  SER A N   1 
ATOM   463  C  CA  . SER A 1 99  ? -63.34435 -124.34206 -18.40947 1.000 53.71724  ? 98  SER A CA  1 
ATOM   464  C  C   . SER A 1 99  ? -63.14053 -125.80982 -18.05327 1.000 57.82117  ? 98  SER A C   1 
ATOM   465  O  O   . SER A 1 99  ? -62.04412 -126.20989 -17.64693 1.000 57.07268  ? 98  SER A O   1 
ATOM   466  C  CB  . SER A 1 99  ? -62.47948 -123.94291 -19.60375 1.000 56.35064  ? 98  SER A CB  1 
ATOM   467  N  N   . GLY A 1 100 ? -64.19645 -126.60593 -18.19232 1.000 57.81604  ? 99  GLY A N   1 
ATOM   468  C  CA  . GLY A 1 100 ? -64.12207 -128.01739 -17.88566 1.000 56.90796  ? 99  GLY A CA  1 
ATOM   469  C  C   . GLY A 1 100 ? -64.28220 -128.29699 -16.40237 1.000 58.91948  ? 99  GLY A C   1 
ATOM   470  O  O   . GLY A 1 100 ? -64.48138 -127.40448 -15.57724 1.000 58.10858  ? 99  GLY A O   1 
ATOM   471  N  N   . PHE A 1 101 ? -64.18695 -129.58090 -16.06242 1.000 57.09780  ? 100 PHE A N   1 
ATOM   472  C  CA  . PHE A 1 101 ? -64.30723 -130.01072 -14.67801 1.000 50.06535  ? 100 PHE A CA  1 
ATOM   473  C  C   . PHE A 1 101 ? -62.96873 -129.88556 -13.96715 1.000 48.32366  ? 100 PHE A C   1 
ATOM   474  O  O   . PHE A 1 101 ? -61.91474 -130.14402 -14.55391 1.000 43.27660  ? 100 PHE A O   1 
ATOM   475  C  CB  . PHE A 1 101 ? -64.77754 -131.46167 -14.59673 1.000 52.91452  ? 100 PHE A CB  1 
ATOM   476  C  CG  . PHE A 1 101 ? -66.13400 -131.69765 -15.17846 1.000 62.54343  ? 100 PHE A CG  1 
ATOM   477  C  CD1 . PHE A 1 101 ? -67.27790 -131.37928 -14.46092 1.000 63.63233  ? 100 PHE A CD1 1 
ATOM   478  C  CD2 . PHE A 1 101 ? -66.26715 -132.25433 -16.44075 1.000 59.79307  ? 100 PHE A CD2 1 
ATOM   479  C  CE1 . PHE A 1 101 ? -68.53171 -131.60629 -14.99855 1.000 66.27005  ? 100 PHE A CE1 1 
ATOM   480  C  CE2 . PHE A 1 101 ? -67.51037 -132.48526 -16.98152 1.000 63.15230  ? 100 PHE A CE2 1 
ATOM   481  C  CZ  . PHE A 1 101 ? -68.64686 -132.16001 -16.26058 1.000 70.32612  ? 100 PHE A CZ  1 
ATOM   482  N  N   . SER A 1 102 ? -63.01394 -129.52481 -12.68804 1.000 45.81939  ? 101 SER A N   1 
ATOM   483  C  CA  . SER A 1 102 ? -61.78410 -129.40725 -11.91623 1.000 48.39675  ? 101 SER A CA  1 
ATOM   484  C  C   . SER A 1 102 ? -62.14096 -129.27748 -10.44015 1.000 43.02959  ? 101 SER A C   1 
ATOM   485  O  O   . SER A 1 102 ? -63.31156 -129.15410 -10.06776 1.000 43.63874  ? 101 SER A O   1 
ATOM   486  C  CB  . SER A 1 102 ? -60.95336 -128.20539 -12.37132 1.000 43.23071  ? 101 SER A CB  1 
ATOM   487  O  OG  . SER A 1 102 ? -61.61018 -127.00297 -11.99668 1.000 42.68216  ? 101 SER A OG  1 
ATOM   488  N  N   . GLY A 1 103 ? -61.10721 -129.29081 -9.60591  1.000 37.12176  ? 102 GLY A N   1 
ATOM   489  C  CA  . GLY A 1 103 ? -61.26967 -129.02859 -8.19062  1.000 36.39552  ? 102 GLY A CA  1 
ATOM   490  C  C   . GLY A 1 103 ? -61.29184 -127.54629 -7.85941  1.000 35.89290  ? 102 GLY A C   1 
ATOM   491  O  O   . GLY A 1 103 ? -60.71438 -127.13167 -6.85593  1.000 34.05842  ? 102 GLY A O   1 
ATOM   492  N  N   . VAL A 1 104 ? -61.94411 -126.73379 -8.68895  1.000 35.09718  ? 103 VAL A N   1 
ATOM   493  C  CA  . VAL A 1 104 ? -62.10510 -125.30272 -8.44308  1.000 33.83761  ? 103 VAL A CA  1 
ATOM   494  C  C   . VAL A 1 104 ? -63.58551 -124.95997 -8.54075  1.000 34.64976  ? 103 VAL A C   1 
ATOM   495  O  O   . VAL A 1 104 ? -64.28242 -125.46667 -9.42608  1.000 38.10527  ? 103 VAL A O   1 
ATOM   496  C  CB  . VAL A 1 104 ? -61.29484 -124.45358 -9.44828  1.000 43.65856  ? 103 VAL A CB  1 
ATOM   497  C  CG1 . VAL A 1 104 ? -61.42172 -122.97328 -9.12197  1.000 44.17104  ? 103 VAL A CG1 1 
ATOM   498  C  CG2 . VAL A 1 104 ? -59.83995 -124.86380 -9.46290  1.000 41.07421  ? 103 VAL A CG2 1 
ATOM   499  N  N   . ILE A 1 105 ? -64.07598 -124.11948 -7.62113  1.000 35.23598  ? 104 ILE A N   1 
ATOM   500  C  CA  . ILE A 1 105 ? -65.42722 -123.58791 -7.76993  1.000 34.88418  ? 104 ILE A CA  1 
ATOM   501  C  C   . ILE A 1 105 ? -65.45475 -122.75205 -9.03649  1.000 41.42364  ? 104 ILE A C   1 
ATOM   502  O  O   . ILE A 1 105 ? -64.71080 -121.77037 -9.16160  1.000 36.47082  ? 104 ILE A O   1 
ATOM   503  C  CB  . ILE A 1 105 ? -65.84925 -122.76940 -6.54363  1.000 36.68968  ? 104 ILE A CB  1 
ATOM   504  C  CG1 . ILE A 1 105 ? -66.10958 -123.68014 -5.33430  1.000 34.24919  ? 104 ILE A CG1 1 
ATOM   505  C  CG2 . ILE A 1 105 ? -67.10745 -121.98176 -6.83568  1.000 31.72637  ? 104 ILE A CG2 1 
ATOM   506  C  CD1 . ILE A 1 105 ? -67.27443 -124.65493 -5.53735  1.000 37.46971  ? 104 ILE A CD1 1 
ATOM   507  N  N   . ARG A 1 106 ? -66.31468 -123.13830 -9.97736  1.000 36.36689  ? 105 ARG A N   1 
ATOM   508  C  CA  . ARG A 1 106 ? -66.33374 -122.55315 -11.31235 1.000 36.42873  ? 105 ARG A CA  1 
ATOM   509  C  C   . ARG A 1 106 ? -67.22465 -121.32292 -11.40395 1.000 33.84547  ? 105 ARG A C   1 
ATOM   510  O  O   . ARG A 1 106 ? -68.30179 -121.25922 -10.79353 1.000 33.91685  ? 105 ARG A O   1 
ATOM   511  C  CB  . ARG A 1 106 ? -66.79054 -123.60003 -12.32321 1.000 33.77687  ? 105 ARG A CB  1 
ATOM   512  C  CG  . ARG A 1 106 ? -65.76268 -124.72589 -12.45801 1.000 44.79396  ? 105 ARG A CG  1 
ATOM   513  C  CD  . ARG A 1 106 ? -66.30737 -125.88763 -13.26748 1.000 49.10173  ? 105 ARG A CD  1 
ATOM   514  N  NE  . ARG A 1 106 ? -66.57435 -125.49207 -14.64246 1.000 50.59710  ? 105 ARG A NE  1 
ATOM   515  C  CZ  . ARG A 1 106 ? -67.27284 -126.21572 -15.50705 1.000 63.86719  ? 105 ARG A CZ  1 
ATOM   516  N  NH1 . ARG A 1 106 ? -67.80727 -127.37777 -15.16231 1.000 57.65052  ? 105 ARG A NH1 1 
ATOM   517  N  NH2 . ARG A 1 106 ? -67.43669 -125.76298 -16.74898 1.000 62.68600  ? 105 ARG A NH2 1 
ATOM   518  N  N   . LEU A 1 107 ? -66.75328 -120.34602 -12.18091 1.000 34.24975  ? 106 LEU A N   1 
ATOM   519  C  CA  . LEU A 1 107 ? -67.52194 -119.15836 -12.51945 1.000 36.00536  ? 106 LEU A CA  1 
ATOM   520  C  C   . LEU A 1 107 ? -68.47204 -119.48456 -13.66246 1.000 41.41205  ? 106 LEU A C   1 
ATOM   521  O  O   . LEU A 1 107 ? -68.03174 -119.84769 -14.76049 1.000 37.21953  ? 106 LEU A O   1 
ATOM   522  C  CB  . LEU A 1 107 ? -66.58779 -118.01753 -12.91521 1.000 37.31992  ? 106 LEU A CB  1 
ATOM   523  C  CG  . LEU A 1 107 ? -67.30211 -116.70979 -13.26588 1.000 37.71941  ? 106 LEU A CG  1 
ATOM   524  C  CD1 . LEU A 1 107 ? -67.77807 -116.01489 -11.97527 1.000 35.42126  ? 106 LEU A CD1 1 
ATOM   525  C  CD2 . LEU A 1 107 ? -66.38473 -115.80398 -14.07602 1.000 37.29020  ? 106 LEU A CD2 1 
ATOM   526  N  N   . LEU A 1 108 ? -69.77097 -119.36046 -13.40354 1.000 36.02587  ? 107 LEU A N   1 
ATOM   527  C  CA  . LEU A 1 108 ? -70.79309 -119.69762 -14.38601 1.000 37.93804  ? 107 LEU A CA  1 
ATOM   528  C  C   . LEU A 1 108 ? -71.21752 -118.49875 -15.22166 1.000 44.81634  ? 107 LEU A C   1 
ATOM   529  O  O   . LEU A 1 108 ? -71.60633 -118.66087 -16.38826 1.000 40.16756  ? 107 LEU A O   1 
ATOM   530  C  CB  . LEU A 1 108 ? -72.01704 -120.27888 -13.67188 1.000 41.43136  ? 107 LEU A CB  1 
ATOM   531  C  CG  . LEU A 1 108 ? -71.73568 -121.47037 -12.74971 1.000 40.56689  ? 107 LEU A CG  1 
ATOM   532  C  CD1 . LEU A 1 108 ? -73.01898 -121.91607 -12.08544 1.000 42.16068  ? 107 LEU A CD1 1 
ATOM   533  C  CD2 . LEU A 1 108 ? -71.08394 -122.61601 -13.52185 1.000 46.22630  ? 107 LEU A CD2 1 
ATOM   534  N  N   . ASP A 1 109 ? -71.14610 -117.30353 -14.64901 1.000 39.86807  ? 108 ASP A N   1 
ATOM   535  C  CA  . ASP A 1 109 ? -71.50586 -116.07460 -15.33825 1.000 43.32758  ? 108 ASP A CA  1 
ATOM   536  C  C   . ASP A 1 109 ? -71.03104 -114.93015 -14.45849 1.000 44.22268  ? 108 ASP A C   1 
ATOM   537  O  O   . ASP A 1 109 ? -70.61364 -115.13857 -13.31698 1.000 37.28338  ? 108 ASP A O   1 
ATOM   538  C  CB  . ASP A 1 109 ? -73.01144 -115.99687 -15.59109 1.000 46.35307  ? 108 ASP A CB  1 
ATOM   539  C  CG  . ASP A 1 109 ? -73.37261 -115.01195 -16.69217 1.000 54.48134  ? 108 ASP A CG  1 
ATOM   540  O  OD1 . ASP A 1 109 ? -72.45570 -114.49296 -17.36835 1.000 47.28780  ? 108 ASP A OD1 1 
ATOM   541  O  OD2 . ASP A 1 109 ? -74.58110 -114.75981 -16.86462 1.000 55.82043  ? 108 ASP A OD2 1 
ATOM   542  N  N   . TRP A 1 110 ? -71.07710 -113.72058 -15.01035 1.000 42.31360  ? 109 TRP A N   1 
ATOM   543  C  CA  . TRP A 1 110 ? -70.74539 -112.52545 -14.25245 1.000 44.36203  ? 109 TRP A CA  1 
ATOM   544  C  C   . TRP A 1 110 ? -71.47357 -111.33687 -14.86287 1.000 48.70470  ? 109 TRP A C   1 
ATOM   545  O  O   . TRP A 1 110 ? -71.91661 -111.38095 -16.01174 1.000 49.54161  ? 109 TRP A O   1 
ATOM   546  C  CB  . TRP A 1 110 ? -69.23124 -112.27776 -14.20851 1.000 38.04961  ? 109 TRP A CB  1 
ATOM   547  C  CG  . TRP A 1 110 ? -68.60699 -112.04133 -15.52931 1.000 42.64377  ? 109 TRP A CG  1 
ATOM   548  C  CD1 . TRP A 1 110 ? -68.12947 -112.99015 -16.39152 1.000 44.49464  ? 109 TRP A CD1 1 
ATOM   549  C  CD2 . TRP A 1 110 ? -68.37733 -110.77503 -16.15819 1.000 43.21012  ? 109 TRP A CD2 1 
ATOM   550  N  NE1 . TRP A 1 110 ? -67.61882 -112.39255 -17.51698 1.000 48.05295  ? 109 TRP A NE1 1 
ATOM   551  C  CE2 . TRP A 1 110 ? -67.75690 -111.03342 -17.40139 1.000 47.61730  ? 109 TRP A CE2 1 
ATOM   552  C  CE3 . TRP A 1 110 ? -68.63967 -109.44931 -15.79652 1.000 45.06600  ? 109 TRP A CE3 1 
ATOM   553  C  CZ2 . TRP A 1 110 ? -67.39640 -110.01342 -18.28656 1.000 46.90814  ? 109 TRP A CZ2 1 
ATOM   554  C  CZ3 . TRP A 1 110 ? -68.27812 -108.43463 -16.67471 1.000 53.17945  ? 109 TRP A CZ3 1 
ATOM   555  C  CH2 . TRP A 1 110 ? -67.66696 -108.72653 -17.91250 1.000 53.96146  ? 109 TRP A CH2 1 
ATOM   556  N  N   . PHE A 1 111 ? -71.58925 -110.27117 -14.07251 1.000 47.68900  ? 110 PHE A N   1 
ATOM   557  C  CA  . PHE A 1 111 ? -72.30686 -109.06301 -14.45469 1.000 52.16549  ? 110 PHE A CA  1 
ATOM   558  C  C   . PHE A 1 111 ? -71.54766 -107.85190 -13.93785 1.000 51.25855  ? 110 PHE A C   1 
ATOM   559  O  O   . PHE A 1 111 ? -70.95107 -107.89338 -12.86165 1.000 42.11629  ? 110 PHE A O   1 
ATOM   560  C  CB  . PHE A 1 111 ? -73.73397 -109.02197 -13.87781 1.000 53.34410  ? 110 PHE A CB  1 
ATOM   561  C  CG  . PHE A 1 111 ? -74.56513 -110.22698 -14.20112 1.000 60.30172  ? 110 PHE A CG  1 
ATOM   562  C  CD1 . PHE A 1 111 ? -74.50313 -111.36123 -13.41029 1.000 61.40294  ? 110 PHE A CD1 1 
ATOM   563  C  CD2 . PHE A 1 111 ? -75.43283 -110.21648 -15.28443 1.000 75.92612  ? 110 PHE A CD2 1 
ATOM   564  C  CE1 . PHE A 1 111 ? -75.27268 -112.47463 -13.70411 1.000 67.93313  ? 110 PHE A CE1 1 
ATOM   565  C  CE2 . PHE A 1 111 ? -76.21023 -111.32386 -15.58248 1.000 78.39823  ? 110 PHE A CE2 1 
ATOM   566  C  CZ  . PHE A 1 111 ? -76.13037 -112.45553 -14.79071 1.000 73.41678  ? 110 PHE A CZ  1 
ATOM   567  N  N   . GLU A 1 112 ? -71.59612 -106.76020 -14.69304 1.000 48.33437  ? 111 GLU A N   1 
ATOM   568  C  CA  . GLU A 1 112 ? -71.06737 -105.48768 -14.22611 1.000 47.77258  ? 111 GLU A CA  1 
ATOM   569  C  C   . GLU A 1 112 ? -72.21325 -104.58253 -13.78457 1.000 49.49925  ? 111 GLU A C   1 
ATOM   570  O  O   . GLU A 1 112 ? -73.23492 -104.47896 -14.47023 1.000 51.68188  ? 111 GLU A O   1 
ATOM   571  C  CB  . GLU A 1 112 ? -70.23206 -104.80146 -15.30486 1.000 51.98385  ? 111 GLU A CB  1 
ATOM   572  C  CG  . GLU A 1 112 ? -69.64287 -103.48499 -14.84684 1.000 52.66918  ? 111 GLU A CG  1 
ATOM   573  C  CD  . GLU A 1 112 ? -68.63926 -102.91818 -15.82007 1.000 57.36314  ? 111 GLU A CD  1 
ATOM   574  O  OE1 . GLU A 1 112 ? -68.40552 -103.54449 -16.87457 1.000 65.71027  ? 111 GLU A OE1 1 
ATOM   575  O  OE2 . GLU A 1 112 ? -68.07677 -101.84727 -15.52432 1.000 57.22497  ? 111 GLU A OE2 1 
ATOM   576  N  N   . ARG A 1 113 ? -72.04292 -103.94864 -12.63333 1.000 48.14624  ? 112 ARG A N   1 
ATOM   577  C  CA  . ARG A 1 113 ? -72.98562 -102.97204 -12.10359 1.000 57.07699  ? 112 ARG A CA  1 
ATOM   578  C  C   . ARG A 1 113 ? -72.27178 -101.62956 -12.01661 1.000 51.97010  ? 112 ARG A C   1 
ATOM   579  O  O   . ARG A 1 113 ? -71.05321 -101.57725 -12.22550 1.000 50.01838  ? 112 ARG A O   1 
ATOM   580  C  CB  . ARG A 1 113 ? -73.51406 -103.41680 -10.73755 1.000 49.12110  ? 112 ARG A CB  1 
ATOM   581  C  CG  . ARG A 1 113 ? -74.59054 -104.48094 -10.81081 1.000 50.11284  ? 112 ARG A CG  1 
ATOM   582  C  CD  . ARG A 1 113 ? -75.03075 -104.86560 -9.42406  1.000 54.96367  ? 112 ARG A CD  1 
ATOM   583  N  NE  . ARG A 1 113 ? -76.31264 -105.55920 -9.40009  1.000 57.92173  ? 112 ARG A NE  1 
ATOM   584  C  CZ  . ARG A 1 113 ? -76.83669 -106.09709 -8.30703  1.000 56.98877  ? 112 ARG A CZ  1 
ATOM   585  N  NH1 . ARG A 1 113 ? -76.19110 -106.07665 -7.15077  1.000 49.68110  ? 112 ARG A NH1 1 
ATOM   586  N  NH2 . ARG A 1 113 ? -78.03614 -106.66656 -8.37460  1.000 54.23841  ? 112 ARG A NH2 1 
ATOM   587  N  N   . PRO A 1 114 ? -72.97863 -100.52607 -11.73064 1.000 57.73380  ? 113 PRO A N   1 
ATOM   588  C  CA  . PRO A 1 114 ? -72.28928 -99.22584  -11.66337 1.000 56.26735  ? 113 PRO A CA  1 
ATOM   589  C  C   . PRO A 1 114 ? -71.10118 -99.21174  -10.71854 1.000 52.51439  ? 113 PRO A C   1 
ATOM   590  O  O   . PRO A 1 114 ? -70.04881 -98.67180  -11.07597 1.000 52.81064  ? 113 PRO A O   1 
ATOM   591  C  CB  . PRO A 1 114 ? -73.39944 -98.27501  -11.19415 1.000 59.40108  ? 113 PRO A CB  1 
ATOM   592  C  CG  . PRO A 1 114 ? -74.63882 -98.88094  -11.72573 1.000 56.81312  ? 113 PRO A CG  1 
ATOM   593  C  CD  . PRO A 1 114 ? -74.43912 -100.37069 -11.59756 1.000 51.84477  ? 113 PRO A CD  1 
ATOM   594  N  N   . ASP A 1 115 ? -71.22894 -99.81455  -9.53405  1.000 49.42477  ? 114 ASP A N   1 
ATOM   595  C  CA  . ASP A 1 115 ? -70.19581 -99.73904  -8.50518  1.000 49.28516  ? 114 ASP A CA  1 
ATOM   596  C  C   . ASP A 1 115 ? -69.59782 -101.09560 -8.14758  1.000 50.99821  ? 114 ASP A C   1 
ATOM   597  O  O   . ASP A 1 115 ? -68.81442 -101.17692 -7.19152  1.000 45.09682  ? 114 ASP A O   1 
ATOM   598  C  CB  . ASP A 1 115 ? -70.75836 -99.08845  -7.23676  1.000 49.75566  ? 114 ASP A CB  1 
ATOM   599  C  CG  . ASP A 1 115 ? -71.31445 -97.69879  -7.48970  1.000 61.14650  ? 114 ASP A CG  1 
ATOM   600  O  OD1 . ASP A 1 115 ? -70.60596 -96.86865  -8.10644  1.000 57.29826  ? 114 ASP A OD1 1 
ATOM   601  O  OD2 . ASP A 1 115 ? -72.46631 -97.44506  -7.07544  1.000 59.06181  ? 114 ASP A OD2 1 
ATOM   602  N  N   . SER A 1 116 ? -69.93527 -102.15803 -8.87724  1.000 42.64661  ? 115 SER A N   1 
ATOM   603  C  CA  . SER A 1 116 ? -69.50219 -103.48904 -8.47669  1.000 48.39021  ? 115 SER A CA  1 
ATOM   604  C  C   . SER A 1 116 ? -69.56192 -104.44761 -9.66231  1.000 43.47607  ? 115 SER A C   1 
ATOM   605  O  O   . SER A 1 116 ? -70.09703 -104.13393 -10.73115 1.000 44.07191  ? 115 SER A O   1 
ATOM   606  C  CB  . SER A 1 116 ? -70.35987 -104.01388 -7.32293  1.000 46.51123  ? 115 SER A CB  1 
ATOM   607  O  OG  . SER A 1 116 ? -71.70403 -104.08310 -7.74361  1.000 47.69839  ? 115 SER A OG  1 
ATOM   608  N  N   . PHE A 1 117 ? -68.97260 -105.61969 -9.44559  1.000 43.38622  ? 116 PHE A N   1 
ATOM   609  C  CA  . PHE A 1 117 ? -69.10180 -106.79307 -10.29689 1.000 45.55061  ? 116 PHE A CA  1 
ATOM   610  C  C   . PHE A 1 117 ? -69.77469 -107.90214 -9.50120  1.000 39.03745  ? 116 PHE A C   1 
ATOM   611  O  O   . PHE A 1 117 ? -69.55387 -108.03008 -8.29565  1.000 38.00128  ? 116 PHE A O   1 
ATOM   612  C  CB  . PHE A 1 117 ? -67.73594 -107.26787 -10.79605 1.000 44.34201  ? 116 PHE A CB  1 
ATOM   613  C  CG  . PHE A 1 117 ? -67.14508 -106.37734 -11.85862 1.000 45.54851  ? 116 PHE A CG  1 
ATOM   614  C  CD1 . PHE A 1 117 ? -66.42785 -105.24004 -11.50988 1.000 44.61958  ? 116 PHE A CD1 1 
ATOM   615  C  CD2 . PHE A 1 117 ? -67.32911 -106.66439 -13.20198 1.000 45.25507  ? 116 PHE A CD2 1 
ATOM   616  C  CE1 . PHE A 1 117 ? -65.89638 -104.40657 -12.49007 1.000 46.75047  ? 116 PHE A CE1 1 
ATOM   617  C  CE2 . PHE A 1 117 ? -66.79052 -105.84481 -14.18191 1.000 52.16563  ? 116 PHE A CE2 1 
ATOM   618  C  CZ  . PHE A 1 117 ? -66.07702 -104.71259 -13.81988 1.000 49.51235  ? 116 PHE A CZ  1 
ATOM   619  N  N   . VAL A 1 118 ? -70.60201 -108.69297 -10.17586 1.000 40.54708  ? 117 VAL A N   1 
ATOM   620  C  CA  . VAL A 1 118 ? -71.34599 -109.78542 -9.55662  1.000 42.66478  ? 117 VAL A CA  1 
ATOM   621  C  C   . VAL A 1 118 ? -70.90937 -111.07840 -10.22787 1.000 45.00899  ? 117 VAL A C   1 
ATOM   622  O  O   . VAL A 1 118 ? -70.93228 -111.17531 -11.46129 1.000 42.99549  ? 117 VAL A O   1 
ATOM   623  C  CB  . VAL A 1 118 ? -72.86694 -109.59493 -9.70038  1.000 42.13809  ? 117 VAL A CB  1 
ATOM   624  C  CG1 . VAL A 1 118 ? -73.59445 -110.56907 -8.81022  1.000 42.85385  ? 117 VAL A CG1 1 
ATOM   625  C  CG2 . VAL A 1 118 ? -73.27427 -108.13885 -9.39389  1.000 46.32080  ? 117 VAL A CG2 1 
ATOM   626  N  N   . LEU A 1 119 ? -70.52990 -112.06661 -9.42270  1.000 39.26544  ? 118 LEU A N   1 
ATOM   627  C  CA  . LEU A 1 119 ? -69.97704 -113.32808 -9.90887  1.000 39.32755  ? 118 LEU A CA  1 
ATOM   628  C  C   . LEU A 1 119 ? -70.93785 -114.44914 -9.55040  1.000 41.62708  ? 118 LEU A C   1 
ATOM   629  O  O   . LEU A 1 119 ? -71.32240 -114.58328 -8.38016  1.000 38.47006  ? 118 LEU A O   1 
ATOM   630  C  CB  . LEU A 1 119 ? -68.60025 -113.61039 -9.28828  1.000 33.53536  ? 118 LEU A CB  1 
ATOM   631  C  CG  . LEU A 1 119 ? -67.34725 -112.90839 -9.83917  1.000 40.28802  ? 118 LEU A CG  1 
ATOM   632  C  CD1 . LEU A 1 119 ? -67.51647 -111.40075 -9.92376  1.000 43.15289  ? 118 LEU A CD1 1 
ATOM   633  C  CD2 . LEU A 1 119 ? -66.12576 -113.24464 -8.99405  1.000 40.69419  ? 118 LEU A CD2 1 
ATOM   634  N  N   . ILE A 1 120 ? -71.32911 -115.24557 -10.54667 1.000 37.80358  ? 119 ILE A N   1 
ATOM   635  C  CA  . ILE A 1 120 ? -72.19652 -116.39973 -10.32174 1.000 38.20380  ? 119 ILE A CA  1 
ATOM   636  C  C   . ILE A 1 120 ? -71.33069 -117.64990 -10.26622 1.000 35.39296  ? 119 ILE A C   1 
ATOM   637  O  O   . ILE A 1 120 ? -70.72308 -118.03745 -11.27239 1.000 34.48080  ? 119 ILE A O   1 
ATOM   638  C  CB  . ILE A 1 120 ? -73.26753 -116.54162 -11.41562 1.000 44.63737  ? 119 ILE A CB  1 
ATOM   639  C  CG1 . ILE A 1 120 ? -74.00428 -115.21825 -11.66347 1.000 44.05490  ? 119 ILE A CG1 1 
ATOM   640  C  CG2 . ILE A 1 120 ? -74.25122 -117.64312 -11.00915 1.000 44.28964  ? 119 ILE A CG2 1 
ATOM   641  C  CD1 . ILE A 1 120 ? -74.78344 -114.72277 -10.45474 1.000 42.48649  ? 119 ILE A CD1 1 
ATOM   642  N  N   . LEU A 1 121 ? -71.30770 -118.30849 -9.11089  1.000 35.95959  ? 120 LEU A N   1 
ATOM   643  C  CA  . LEU A 1 121 ? -70.44365 -119.45846 -8.88779  1.000 30.73399  ? 120 LEU A CA  1 
ATOM   644  C  C   . LEU A 1 121 ? -71.26970 -120.70370 -8.61210  1.000 38.19210  ? 120 LEU A C   1 
ATOM   645  O  O   . LEU A 1 121 ? -72.42180 -120.63185 -8.17974  1.000 37.57582  ? 120 LEU A O   1 
ATOM   646  C  CB  . LEU A 1 121 ? -69.49611 -119.21134 -7.70864  1.000 40.58529  ? 120 LEU A CB  1 
ATOM   647  C  CG  . LEU A 1 121 ? -68.76383 -117.87897 -7.81688  1.000 41.20005  ? 120 LEU A CG  1 
ATOM   648  C  CD1 . LEU A 1 121 ? -68.44601 -117.34075 -6.43230  1.000 40.43615  ? 120 LEU A CD1 1 
ATOM   649  C  CD2 . LEU A 1 121 ? -67.51199 -118.07507 -8.62503  1.000 37.16036  ? 120 LEU A CD2 1 
ATOM   650  N  N   . GLU A 1 122 ? -70.65967 -121.85481 -8.86065  1.000 33.98783  ? 121 GLU A N   1 
ATOM   651  C  CA  . GLU A 1 122 ? -71.23443 -123.10728 -8.39709  1.000 39.16176  ? 121 GLU A CA  1 
ATOM   652  C  C   . GLU A 1 122 ? -71.44768 -123.06431 -6.89620  1.000 38.61875  ? 121 GLU A C   1 
ATOM   653  O  O   . GLU A 1 122 ? -70.69851 -122.41940 -6.15880  1.000 38.66016  ? 121 GLU A O   1 
ATOM   654  C  CB  . GLU A 1 122 ? -70.31105 -124.28047 -8.70334  1.000 43.30836  ? 121 GLU A CB  1 
ATOM   655  C  CG  . GLU A 1 122 ? -69.92074 -124.42529 -10.14165 1.000 41.24683  ? 121 GLU A CG  1 
ATOM   656  C  CD  . GLU A 1 122 ? -69.01298 -125.62947 -10.32854 1.000 55.35498  ? 121 GLU A CD  1 
ATOM   657  O  OE1 . GLU A 1 122 ? -67.96906 -125.70910 -9.61838  1.000 42.38185  ? 121 GLU A OE1 1 
ATOM   658  O  OE2 . GLU A 1 122 ? -69.36791 -126.50028 -11.15964 1.000 53.83330  ? 121 GLU A OE2 1 
ATOM   659  N  N   . ARG A 1 123 ? -72.46535 -123.78350 -6.43194  1.000 37.74700  ? 122 ARG A N   1 
ATOM   660  C  CA  . ARG A 1 123 ? -72.67225 -123.96863 -4.99844  1.000 39.71064  ? 122 ARG A CA  1 
ATOM   661  C  C   . ARG A 1 123 ? -72.91946 -125.44526 -4.74792  1.000 39.79338  ? 122 ARG A C   1 
ATOM   662  O  O   . ARG A 1 123 ? -74.06504 -125.90709 -4.79486  1.000 39.65433  ? 122 ARG A O   1 
ATOM   663  C  CB  . ARG A 1 123 ? -73.82718 -123.11527 -4.47166  1.000 39.47334  ? 122 ARG A CB  1 
ATOM   664  C  CG  . ARG A 1 123 ? -74.14203 -123.37367 -2.99354  1.000 44.38150  ? 122 ARG A CG  1 
ATOM   665  C  CD  . ARG A 1 123 ? -75.00095 -122.27889 -2.38621  1.000 41.84804  ? 122 ARG A CD  1 
ATOM   666  N  NE  . ARG A 1 123 ? -76.27703 -122.10758 -3.07034  1.000 49.77909  ? 122 ARG A NE  1 
ATOM   667  C  CZ  . ARG A 1 123 ? -77.39024 -122.75717 -2.75576  1.000 50.48417  ? 122 ARG A CZ  1 
ATOM   668  N  NH1 . ARG A 1 123 ? -77.40986 -123.66792 -1.79791  1.000 48.97255  ? 122 ARG A NH1 1 
ATOM   669  N  NH2 . ARG A 1 123 ? -78.50968 -122.49009 -3.42704  1.000 50.16252  ? 122 ARG A NH2 1 
ATOM   670  N  N   . PRO A 1 124 ? -71.87258 -126.22321 -4.49263  1.000 39.76568  ? 123 PRO A N   1 
ATOM   671  C  CA  . PRO A 1 124 ? -72.09824 -127.60065 -4.04694  1.000 43.78272  ? 123 PRO A CA  1 
ATOM   672  C  C   . PRO A 1 124 ? -72.80002 -127.62337 -2.69557  1.000 45.98431  ? 123 PRO A C   1 
ATOM   673  O  O   . PRO A 1 124 ? -72.74071 -126.67439 -1.91012  1.000 39.62972  ? 123 PRO A O   1 
ATOM   674  C  CB  . PRO A 1 124 ? -70.68968 -128.19647 -3.96460  1.000 41.05372  ? 123 PRO A CB  1 
ATOM   675  C  CG  . PRO A 1 124 ? -69.74720 -127.03146 -4.07861  1.000 45.06068  ? 123 PRO A CG  1 
ATOM   676  C  CD  . PRO A 1 124 ? -70.46657 -125.96344 -4.81843  1.000 37.55981  ? 123 PRO A CD  1 
ATOM   677  N  N   . GLU A 1 125 ? -73.47371 -128.72489 -2.42976  1.000 40.31755  ? 124 GLU A N   1 
ATOM   678  C  CA  . GLU A 1 125 ? -74.22467 -128.85549 -1.19291  1.000 46.82570  ? 124 GLU A CA  1 
ATOM   679  C  C   . GLU A 1 125 ? -74.31753 -130.33472 -0.83917  1.000 48.79100  ? 124 GLU A C   1 
ATOM   680  O  O   . GLU A 1 125 ? -74.60730 -131.15648 -1.71464  1.000 42.27444  ? 124 GLU A O   1 
ATOM   681  C  CB  . GLU A 1 125 ? -75.61796 -128.22957 -1.35233  1.000 47.36970  ? 124 GLU A CB  1 
ATOM   682  C  CG  . GLU A 1 125 ? -76.12313 -127.50962 -0.10665  1.000 62.76931  ? 124 GLU A CG  1 
ATOM   683  C  CD  . GLU A 1 125 ? -75.36560 -126.21804 0.18965   1.000 60.85499  ? 124 GLU A CD  1 
ATOM   684  O  OE1 . GLU A 1 125 ? -75.43724 -125.26542 -0.62575  1.000 55.60211  ? 124 GLU A OE1 1 
ATOM   685  O  OE2 . GLU A 1 125 ? -74.71550 -126.15585 1.25643   1.000 69.56423  ? 124 GLU A OE2 1 
ATOM   686  N  N   . PRO A 1 126 ? -74.04199 -130.72863 0.42108   1.000 46.21888  ? 125 PRO A N   1 
ATOM   687  C  CA  . PRO A 1 126 ? -73.59515 -129.90952 1.54614   1.000 41.76947  ? 125 PRO A CA  1 
ATOM   688  C  C   . PRO A 1 126 ? -72.08813 -129.67973 1.50359   1.000 43.59759  ? 125 PRO A C   1 
ATOM   689  O  O   . PRO A 1 126 ? -71.35085 -130.48824 0.94795   1.000 41.95572  ? 125 PRO A O   1 
ATOM   690  C  CB  . PRO A 1 126 ? -74.00885 -130.74616 2.75825   1.000 41.19110  ? 125 PRO A CB  1 
ATOM   691  C  CG  . PRO A 1 126 ? -73.81584 -132.15537 2.28513   1.000 48.73403  ? 125 PRO A CG  1 
ATOM   692  C  CD  . PRO A 1 126 ? -74.19711 -132.14474 0.81466   1.000 48.31127  ? 125 PRO A CD  1 
ATOM   693  N  N   . VAL A 1 127 ? -71.61873 -128.59081 2.10719   1.000 38.24105  ? 126 VAL A N   1 
ATOM   694  C  CA  . VAL A 1 127 ? -70.22015 -128.18445 2.06089   1.000 36.48156  ? 126 VAL A CA  1 
ATOM   695  C  C   . VAL A 1 127 ? -69.79012 -127.75519 3.45887   1.000 42.93406  ? 126 VAL A C   1 
ATOM   696  O  O   . VAL A 1 127 ? -70.59721 -127.27514 4.26403   1.000 37.48800  ? 126 VAL A O   1 
ATOM   697  C  CB  . VAL A 1 127 ? -70.01490 -127.03863 1.02568   1.000 45.42398  ? 126 VAL A CB  1 
ATOM   698  C  CG1 . VAL A 1 127 ? -68.98789 -126.03399 1.49154   1.000 46.90002  ? 126 VAL A CG1 1 
ATOM   699  C  CG2 . VAL A 1 127 ? -69.61453 -127.58860 -0.32406  1.000 36.96661  ? 126 VAL A CG2 1 
ATOM   700  N  N   . GLN A 1 128 ? -68.51037 -127.95646 3.75789   1.000 38.19706  ? 127 GLN A N   1 
ATOM   701  C  CA  . GLN A 1 128 ? -67.87385 -127.31543 4.89627   1.000 35.66925  ? 127 GLN A CA  1 
ATOM   702  C  C   . GLN A 1 128 ? -66.48135 -126.91079 4.45220   1.000 37.61009  ? 127 GLN A C   1 
ATOM   703  O  O   . GLN A 1 128 ? -65.82843 -127.65468 3.71456   1.000 36.54480  ? 127 GLN A O   1 
ATOM   704  C  CB  . GLN A 1 128 ? -67.79722 -128.24495 6.11772   1.000 38.27980  ? 127 GLN A CB  1 
ATOM   705  C  CG  . GLN A 1 128 ? -67.17362 -127.59846 7.33630   1.000 33.45577  ? 127 GLN A CG  1 
ATOM   706  C  CD  . GLN A 1 128 ? -67.11771 -128.53818 8.52080   1.000 39.72484  ? 127 GLN A CD  1 
ATOM   707  O  OE1 . GLN A 1 128 ? -66.78210 -129.71194 8.37559   1.000 40.04150  ? 127 GLN A OE1 1 
ATOM   708  N  NE2 . GLN A 1 128 ? -67.45698 -128.02947 9.69370   1.000 42.55875  ? 127 GLN A NE2 1 
ATOM   709  N  N   . ASP A 1 129 ? -66.02916 -125.73357 4.87157   1.000 34.45569  ? 128 ASP A N   1 
ATOM   710  C  CA  . ASP A 1 129 ? -64.68654 -125.39129 4.43084   1.000 37.55792  ? 128 ASP A CA  1 
ATOM   711  C  C   . ASP A 1 129 ? -63.66483 -126.14954 5.27815   1.000 36.33355  ? 128 ASP A C   1 
ATOM   712  O  O   . ASP A 1 129 ? -63.95432 -126.62281 6.38320   1.000 34.49534  ? 128 ASP A O   1 
ATOM   713  C  CB  . ASP A 1 129 ? -64.45021 -123.86692 4.42687   1.000 33.94385  ? 128 ASP A CB  1 
ATOM   714  C  CG  . ASP A 1 129 ? -64.27729 -123.25359 5.80989   1.000 43.28467  ? 128 ASP A CG  1 
ATOM   715  O  OD1 . ASP A 1 129 ? -63.49700 -123.75764 6.65024   1.000 43.93464  ? 128 ASP A OD1 1 
ATOM   716  O  OD2 . ASP A 1 129 ? -64.89406 -122.19502 6.04469   1.000 49.94979  ? 128 ASP A OD2 1 
ATOM   717  N  N   . LEU A 1 130 ? -62.46502 -126.30094 4.71936   1.000 33.69213  ? 129 LEU A N   1 
ATOM   718  C  CA  . LEU A 1 130 ? -61.47039 -127.15732 5.35701   1.000 32.71062  ? 129 LEU A CA  1 
ATOM   719  C  C   . LEU A 1 130 ? -60.96563 -126.57273 6.66850   1.000 33.30828  ? 129 LEU A C   1 
ATOM   720  O  O   . LEU A 1 130 ? -60.56976 -127.33194 7.56289   1.000 32.06786  ? 129 LEU A O   1 
ATOM   721  C  CB  . LEU A 1 130 ? -60.30371 -127.41427 4.38918   1.000 29.15281  ? 129 LEU A CB  1 
ATOM   722  C  CG  . LEU A 1 130 ? -59.17955 -128.31261 4.92290   1.000 31.92996  ? 129 LEU A CG  1 
ATOM   723  C  CD1 . LEU A 1 130 ? -59.67530 -129.71523 5.26502   1.000 27.96668  ? 129 LEU A CD1 1 
ATOM   724  C  CD2 . LEU A 1 130 ? -58.03584 -128.40438 3.91271   1.000 29.04778  ? 129 LEU A CD2 1 
ATOM   725  N  N   . PHE A 1 131 ? -60.96751 -125.23902 6.82205   1.000 32.76356  ? 130 PHE A N   1 
ATOM   726  C  CA  . PHE A 1 131 ? -60.61000 -124.67199 8.12288   1.000 32.36410  ? 130 PHE A CA  1 
ATOM   727  C  C   . PHE A 1 131 ? -61.56215 -125.17051 9.21392   1.000 35.13700  ? 130 PHE A C   1 
ATOM   728  O  O   . PHE A 1 131 ? -61.12415 -125.68157 10.25299  1.000 32.66253  ? 130 PHE A O   1 
ATOM   729  C  CB  . PHE A 1 131 ? -60.59537 -123.13612 8.07639   1.000 32.94064  ? 130 PHE A CB  1 
ATOM   730  C  CG  . PHE A 1 131 ? -60.19277 -122.51198 9.38761   1.000 34.29373  ? 130 PHE A CG  1 
ATOM   731  C  CD1 . PHE A 1 131 ? -61.13074 -122.31855 10.39998  1.000 36.52984  ? 130 PHE A CD1 1 
ATOM   732  C  CD2 . PHE A 1 131 ? -58.87757 -122.17022 9.63389   1.000 34.09899  ? 130 PHE A CD2 1 
ATOM   733  C  CE1 . PHE A 1 131 ? -60.75756 -121.79086 11.63101  1.000 40.01922  ? 130 PHE A CE1 1 
ATOM   734  C  CE2 . PHE A 1 131 ? -58.49794 -121.62350 10.85673  1.000 34.89345  ? 130 PHE A CE2 1 
ATOM   735  C  CZ  . PHE A 1 131 ? -59.43944 -121.43392 11.85650  1.000 41.72714  ? 130 PHE A CZ  1 
ATOM   736  N  N   . ASP A 1 132 ? -62.87702 -125.03691 8.98945   1.000 35.88382  ? 131 ASP A N   1 
ATOM   737  C  CA  . ASP A 1 132 ? -63.85299 -125.48204 9.98520   1.000 35.49441  ? 131 ASP A CA  1 
ATOM   738  C  C   . ASP A 1 132 ? -63.79980 -126.99133 10.18199  1.000 31.27476  ? 131 ASP A C   1 
ATOM   739  O  O   . ASP A 1 132 ? -64.00164 -127.48814 11.29472  1.000 39.92664  ? 131 ASP A O   1 
ATOM   740  C  CB  . ASP A 1 132 ? -65.26248 -125.06978 9.56520   1.000 37.57742  ? 131 ASP A CB  1 
ATOM   741  C  CG  . ASP A 1 132 ? -65.49174 -123.57912 9.67236   1.000 43.76511  ? 131 ASP A CG  1 
ATOM   742  O  OD1 . ASP A 1 132 ? -64.77376 -122.91395 10.44991  1.000 43.76202  ? 131 ASP A OD1 1 
ATOM   743  O  OD2 . ASP A 1 132 ? -66.39979 -123.07834 8.97984   1.000 48.01480  ? 131 ASP A OD2 1 
ATOM   744  N  N   . PHE A 1 133 ? -63.57694 -127.73467 9.09892   1.000 35.10278  ? 132 PHE A N   1 
ATOM   745  C  CA  . PHE A 1 133 ? -63.48990 -129.18783 9.18554   1.000 35.46515  ? 132 PHE A CA  1 
ATOM   746  C  C   . PHE A 1 133 ? -62.35725 -129.61280 10.11647  1.000 35.66537  ? 132 PHE A C   1 
ATOM   747  O  O   . PHE A 1 133 ? -62.53247 -130.48469 10.97509  1.000 34.29843  ? 132 PHE A O   1 
ATOM   748  C  CB  . PHE A 1 133 ? -63.29461 -129.74457 7.77388   1.000 33.29259  ? 132 PHE A CB  1 
ATOM   749  C  CG  . PHE A 1 133 ? -63.30840 -131.24657 7.68728   1.000 37.70602  ? 132 PHE A CG  1 
ATOM   750  C  CD1 . PHE A 1 133 ? -64.50783 -131.93564 7.56777   1.000 35.14353  ? 132 PHE A CD1 1 
ATOM   751  C  CD2 . PHE A 1 133 ? -62.11781 -131.96762 7.68545   1.000 38.36236  ? 132 PHE A CD2 1 
ATOM   752  C  CE1 . PHE A 1 133 ? -64.52414 -133.30950 7.45745   1.000 37.86773  ? 132 PHE A CE1 1 
ATOM   753  C  CE2 . PHE A 1 133 ? -62.12602 -133.36308 7.59204   1.000 34.66687  ? 132 PHE A CE2 1 
ATOM   754  C  CZ  . PHE A 1 133 ? -63.32318 -134.02727 7.47263   1.000 40.14806  ? 132 PHE A CZ  1 
ATOM   755  N  N   . ILE A 1 134 ? -61.18687 -128.98977 9.96865   1.000 35.25623  ? 133 ILE A N   1 
ATOM   756  C  CA  . ILE A 1 134 ? -60.03333 -129.32713 10.80197  1.000 33.90205  ? 133 ILE A CA  1 
ATOM   757  C  C   . ILE A 1 134 ? -60.23650 -128.85892 12.24131  1.000 36.09992  ? 133 ILE A C   1 
ATOM   758  O  O   . ILE A 1 134 ? -59.85521 -129.55088 13.20038  1.000 38.18783  ? 133 ILE A O   1 
ATOM   759  C  CB  . ILE A 1 134 ? -58.75745 -128.72816 10.18339  1.000 32.40412  ? 133 ILE A CB  1 
ATOM   760  C  CG1 . ILE A 1 134 ? -58.39294 -129.49421 8.90142   1.000 31.66923  ? 133 ILE A CG1 1 
ATOM   761  C  CG2 . ILE A 1 134 ? -57.61225 -128.75957 11.19113  1.000 33.21237  ? 133 ILE A CG2 1 
ATOM   762  C  CD1 . ILE A 1 134 ? -57.26934 -128.86226 8.10695   1.000 31.40598  ? 133 ILE A CD1 1 
ATOM   763  N  N   . THR A 1 135 ? -60.81443 -127.66910 12.42480  1.000 36.59487  ? 134 THR A N   1 
ATOM   764  C  CA  . THR A 1 135 ? -61.15272 -127.23672 13.77938  1.000 37.37487  ? 134 THR A CA  1 
ATOM   765  C  C   . THR A 1 135 ? -62.05109 -128.25375 14.47128  1.000 37.85633  ? 134 THR A C   1 
ATOM   766  O  O   . THR A 1 135 ? -61.81628 -128.61595 15.62840  1.000 36.19730  ? 134 THR A O   1 
ATOM   767  C  CB  . THR A 1 135 ? -61.83306 -125.87007 13.74201  1.000 37.79722  ? 134 THR A CB  1 
ATOM   768  O  OG1 . THR A 1 135 ? -60.92598 -124.89884 13.20479  1.000 36.87918  ? 134 THR A OG1 1 
ATOM   769  C  CG2 . THR A 1 135 ? -62.27768 -125.45275 15.15845  1.000 45.24031  ? 134 THR A CG2 1 
ATOM   770  N  N   . GLU A 1 136 ? -63.06782 -128.75146 13.77087  1.000 39.75829  ? 135 GLU A N   1 
ATOM   771  C  CA  . GLU A 1 136 ? -64.03749 -129.62322 14.43141  1.000 42.27878  ? 135 GLU A CA  1 
ATOM   772  C  C   . GLU A 1 136 ? -63.48298 -131.02508 14.63353  1.000 42.89576  ? 135 GLU A C   1 
ATOM   773  O  O   . GLU A 1 136 ? -63.76338 -131.66920 15.64803  1.000 44.63499  ? 135 GLU A O   1 
ATOM   774  C  CB  . GLU A 1 136 ? -65.33317 -129.68750 13.62430  1.000 45.82847  ? 135 GLU A CB  1 
ATOM   775  C  CG  . GLU A 1 136 ? -66.10300 -128.38467 13.56021  1.000 51.90511  ? 135 GLU A CG  1 
ATOM   776  C  CD  . GLU A 1 136 ? -67.43032 -128.53160 12.82661  1.000 65.05682  ? 135 GLU A CD  1 
ATOM   777  O  OE1 . GLU A 1 136 ? -67.69425 -129.62217 12.26444  1.000 59.67879  ? 135 GLU A OE1 1 
ATOM   778  O  OE2 . GLU A 1 136 ? -68.20766 -127.55311 12.81039  1.000 70.73106  ? 135 GLU A OE2 1 
ATOM   779  N  N   . ARG A 1 137 ? -62.69525 -131.51976 13.68939  1.000 37.64505  ? 136 ARG A N   1 
ATOM   780  C  CA  . ARG A 1 137 ? -62.23517 -132.89601 13.77018  1.000 42.06021  ? 136 ARG A CA  1 
ATOM   781  C  C   . ARG A 1 137 ? -60.83779 -133.02893 14.34857  1.000 42.71002  ? 136 ARG A C   1 
ATOM   782  O  O   . ARG A 1 137 ? -60.46483 -134.12825 14.76159  1.000 42.93266  ? 136 ARG A O   1 
ATOM   783  C  CB  . ARG A 1 137 ? -62.32521 -133.54568 12.38003  1.000 48.62750  ? 136 ARG A CB  1 
ATOM   784  C  CG  . ARG A 1 137 ? -63.80026 -133.72565 12.01801  1.000 55.66617  ? 136 ARG A CG  1 
ATOM   785  C  CD  . ARG A 1 137 ? -64.07138 -134.38127 10.69517  1.000 58.45446  ? 136 ARG A CD  1 
ATOM   786  N  NE  . ARG A 1 137 ? -63.50140 -135.71475 10.55778  1.000 58.72498  ? 136 ARG A NE  1 
ATOM   787  C  CZ  . ARG A 1 137 ? -64.03323 -136.67107 9.80728   1.000 56.68431  ? 136 ARG A CZ  1 
ATOM   788  N  NH1 . ARG A 1 137 ? -65.20803 -136.51007 9.21514   1.000 52.44366  ? 136 ARG A NH1 1 
ATOM   789  N  NH2 . ARG A 1 137 ? -63.37305 -137.81769 9.64906   1.000 50.90750  ? 136 ARG A NH2 1 
ATOM   790  N  N   . GLY A 1 138 ? -60.08623 -131.93609 14.45447  1.000 42.88645  ? 137 GLY A N   1 
ATOM   791  C  CA  . GLY A 1 138 ? -58.71510 -132.03037 14.90067  1.000 40.68310  ? 137 GLY A CA  1 
ATOM   792  C  C   . GLY A 1 138 ? -57.82299 -132.50754 13.76960  1.000 40.86849  ? 137 GLY A C   1 
ATOM   793  O  O   . GLY A 1 138 ? -58.21408 -132.53540 12.59408  1.000 38.04561  ? 137 GLY A O   1 
ATOM   794  N  N   . ALA A 1 139 ? -56.60190 -132.89504 14.13599  1.000 37.60446  ? 138 ALA A N   1 
ATOM   795  C  CA  . ALA A 1 139 ? -55.66121 -133.43604 13.15308  1.000 37.65871  ? 138 ALA A CA  1 
ATOM   796  C  C   . ALA A 1 139 ? -56.29492 -134.60053 12.39406  1.000 32.51150  ? 138 ALA A C   1 
ATOM   797  O  O   . ALA A 1 139 ? -56.92223 -135.48027 12.99497  1.000 30.32294  ? 138 ALA A O   1 
ATOM   798  C  CB  . ALA A 1 139 ? -54.38582 -133.89374 13.87174  1.000 35.98334  ? 138 ALA A CB  1 
ATOM   799  N  N   . LEU A 1 140 ? -56.15612 -134.59514 11.06669  1.000 33.20864  ? 139 LEU A N   1 
ATOM   800  C  CA  . LEU A 1 140 ? -56.75672 -135.64441 10.24510  1.000 33.02835  ? 139 LEU A CA  1 
ATOM   801  C  C   . LEU A 1 140 ? -55.87998 -136.89339 10.18471  1.000 30.78514  ? 139 LEU A C   1 
ATOM   802  O  O   . LEU A 1 140 ? -54.65186 -136.79940 10.10578  1.000 32.44690  ? 139 LEU A O   1 
ATOM   803  C  CB  . LEU A 1 140 ? -56.98471 -135.12902 8.82366   1.000 32.64542  ? 139 LEU A CB  1 
ATOM   804  C  CG  . LEU A 1 140 ? -57.68802 -133.77937 8.73137   1.000 29.51566  ? 139 LEU A CG  1 
ATOM   805  C  CD1 . LEU A 1 140 ? -57.87909 -133.33761 7.27338   1.000 32.22337  ? 139 LEU A CD1 1 
ATOM   806  C  CD2 . LEU A 1 140 ? -59.02709 -133.83852 9.50193   1.000 36.65799  ? 139 LEU A CD2 1 
ATOM   807  N  N   . GLN A 1 141 ? -56.52337 -138.06610 10.17753  1.000 31.51622  ? 140 GLN A N   1 
ATOM   808  C  CA  . GLN A 1 141 ? -55.83360 -139.30155 9.81332   1.000 31.50984  ? 140 GLN A CA  1 
ATOM   809  C  C   . GLN A 1 141 ? -55.03602 -139.09100 8.53346   1.000 35.05760  ? 140 GLN A C   1 
ATOM   810  O  O   . GLN A 1 141 ? -55.48445 -138.39096 7.62227   1.000 30.78446  ? 140 GLN A O   1 
ATOM   811  C  CB  . GLN A 1 141 ? -56.82792 -140.44054 9.58155   1.000 32.40052  ? 140 GLN A CB  1 
ATOM   812  C  CG  . GLN A 1 141 ? -57.59412 -140.91854 10.79842  1.000 47.13507  ? 140 GLN A CG  1 
ATOM   813  C  CD  . GLN A 1 141 ? -58.58080 -142.02774 10.42680  1.000 54.48883  ? 140 GLN A CD  1 
ATOM   814  O  OE1 . GLN A 1 141 ? -58.35406 -142.78648 9.47352   1.000 52.17992  ? 140 GLN A OE1 1 
ATOM   815  N  NE2 . GLN A 1 141 ? -59.68100 -142.11364 11.16450  1.000 66.00828  ? 140 GLN A NE2 1 
ATOM   816  N  N   . GLU A 1 142 ? -53.86905 -139.73659 8.44155   1.000 31.73704  ? 141 GLU A N   1 
ATOM   817  C  CA  . GLU A 1 142 ? -53.02001 -139.49967 7.27134   1.000 31.38678  ? 141 GLU A CA  1 
ATOM   818  C  C   . GLU A 1 142 ? -53.68889 -139.96857 5.98210   1.000 31.70448  ? 141 GLU A C   1 
ATOM   819  O  O   . GLU A 1 142 ? -53.52955 -139.33144 4.93583   1.000 30.28688  ? 141 GLU A O   1 
ATOM   820  C  CB  . GLU A 1 142 ? -51.65593 -140.16638 7.44930   1.000 32.14765  ? 141 GLU A CB  1 
ATOM   821  C  CG  . GLU A 1 142 ? -50.86724 -139.53616 8.61400   1.000 35.91243  ? 141 GLU A CG  1 
ATOM   822  C  CD  . GLU A 1 142 ? -49.38360 -139.89594 8.63869   1.000 35.87030  ? 141 GLU A CD  1 
ATOM   823  O  OE1 . GLU A 1 142 ? -48.83968 -140.43240 7.63592   1.000 34.38849  ? 141 GLU A OE1 1 
ATOM   824  O  OE2 . GLU A 1 142 ? -48.75161 -139.60291 9.67480   1.000 36.57088  ? 141 GLU A OE2 1 
ATOM   825  N  N   . GLU A 1 143 ? -54.43537 -141.07592 6.03201   1.000 31.22685  ? 142 GLU A N   1 
ATOM   826  C  CA  . GLU A 1 143 ? -55.15994 -141.51886 4.83809   1.000 33.42782  ? 142 GLU A CA  1 
ATOM   827  C  C   . GLU A 1 143 ? -56.08546 -140.42261 4.31558   1.000 32.09035  ? 142 GLU A C   1 
ATOM   828  O  O   . GLU A 1 143 ? -56.20587 -140.22151 3.09765   1.000 30.96677  ? 142 GLU A O   1 
ATOM   829  C  CB  . GLU A 1 143 ? -55.95995 -142.79076 5.14427   1.000 36.99967  ? 142 GLU A CB  1 
ATOM   830  C  CG  . GLU A 1 143 ? -56.83835 -143.25960 3.96006   1.000 38.19403  ? 142 GLU A CG  1 
ATOM   831  C  CD  . GLU A 1 143 ? -57.71753 -144.45740 4.30337   1.000 44.41149  ? 142 GLU A CD  1 
ATOM   832  O  OE1 . GLU A 1 143 ? -58.78898 -144.26299 4.91844   1.000 38.27360  ? 142 GLU A OE1 1 
ATOM   833  O  OE2 . GLU A 1 143 ? -57.33487 -145.59551 3.96550   1.000 41.02533  ? 142 GLU A OE2 1 
ATOM   834  N  N   . LEU A 1 144 ? -56.75160 -139.70260 5.22571   1.000 33.06133  ? 143 LEU A N   1 
ATOM   835  C  CA  . LEU A 1 144 ? -57.65517 -138.63033 4.81429   1.000 30.21062  ? 143 LEU A CA  1 
ATOM   836  C  C   . LEU A 1 144 ? -56.87275 -137.41812 4.34542   1.000 30.97978  ? 143 LEU A C   1 
ATOM   837  O  O   . LEU A 1 144 ? -57.21072 -136.81379 3.31869   1.000 30.56611  ? 143 LEU A O   1 
ATOM   838  C  CB  . LEU A 1 144 ? -58.59339 -138.24142 5.96887   1.000 30.81574  ? 143 LEU A CB  1 
ATOM   839  C  CG  . LEU A 1 144 ? -59.58960 -137.11334 5.63865   1.000 32.14441  ? 143 LEU A CG  1 
ATOM   840  C  CD1 . LEU A 1 144 ? -60.45771 -137.48434 4.45960   1.000 33.86069  ? 143 LEU A CD1 1 
ATOM   841  C  CD2 . LEU A 1 144 ? -60.49189 -136.73973 6.82903   1.000 36.18535  ? 143 LEU A CD2 1 
ATOM   842  N  N   . ALA A 1 145 ? -55.82405 -137.04368 5.09150   1.000 30.20909  ? 144 ALA A N   1 
ATOM   843  C  CA  . ALA A 1 145 ? -54.96851 -135.94898 4.64998   1.000 29.45950  ? 144 ALA A CA  1 
ATOM   844  C  C   . ALA A 1 145 ? -54.37564 -136.23644 3.27860   1.000 27.55584  ? 144 ALA A C   1 
ATOM   845  O  O   . ALA A 1 145 ? -54.25204 -135.32704 2.45391   1.000 29.23728  ? 144 ALA A O   1 
ATOM   846  C  CB  . ALA A 1 145 ? -53.85025 -135.69939 5.66328   1.000 24.98280  ? 144 ALA A CB  1 
ATOM   847  N  N   . ARG A 1 146 ? -53.98258 -137.49273 3.02178   1.000 28.91886  ? 145 ARG A N   1 
ATOM   848  C  CA  . ARG A 1 146 ? -53.41172 -137.83652 1.71461   1.000 30.57319  ? 145 ARG A CA  1 
ATOM   849  C  C   . ARG A 1 146 ? -54.41309 -137.57983 0.59462   1.000 29.29455  ? 145 ARG A C   1 
ATOM   850  O  O   . ARG A 1 146 ? -54.08505 -136.97458 -0.43778  1.000 26.94285  ? 145 ARG A O   1 
ATOM   851  C  CB  . ARG A 1 146 ? -52.96196 -139.30208 1.70413   1.000 30.40245  ? 145 ARG A CB  1 
ATOM   852  C  CG  . ARG A 1 146 ? -52.57495 -139.83926 0.29476   1.000 28.53221  ? 145 ARG A CG  1 
ATOM   853  C  CD  . ARG A 1 146 ? -52.14812 -141.32308 0.34315   1.000 30.55590  ? 145 ARG A CD  1 
ATOM   854  N  NE  . ARG A 1 146 ? -51.10228 -141.53420 1.34439   1.000 32.96754  ? 145 ARG A NE  1 
ATOM   855  C  CZ  . ARG A 1 146 ? -51.25411 -142.20615 2.48389   1.000 34.74391  ? 145 ARG A CZ  1 
ATOM   856  N  NH1 . ARG A 1 146 ? -52.37070 -142.86299 2.77011   1.000 32.34355  ? 145 ARG A NH1 1 
ATOM   857  N  NH2 . ARG A 1 146 ? -50.25722 -142.22827 3.35491   1.000 32.61966  ? 145 ARG A NH2 1 
ATOM   858  N  N   . SER A 1 147 ? -55.64556 -138.04317 0.78197   1.000 30.41557  ? 146 SER A N   1 
ATOM   859  C  CA  . SER A 1 147 ? -56.67419 -137.84876 -0.23182  1.000 28.40691  ? 146 SER A CA  1 
ATOM   860  C  C   . SER A 1 147 ? -56.94873 -136.36628 -0.44566  1.000 28.71477  ? 146 SER A C   1 
ATOM   861  O  O   . SER A 1 147 ? -57.03450 -135.89537 -1.58372  1.000 31.64555  ? 146 SER A O   1 
ATOM   862  C  CB  . SER A 1 147 ? -57.95000 -138.58237 0.19034   1.000 31.63701  ? 146 SER A CB  1 
ATOM   863  O  OG  . SER A 1 147 ? -59.02865 -138.19417 -0.63758  1.000 35.41415  ? 146 SER A OG  1 
ATOM   864  N  N   . PHE A 1 148 ? -57.08526 -135.60683 0.64652   1.000 26.63848  ? 147 PHE A N   1 
ATOM   865  C  CA  . PHE A 1 148 ? -57.33616 -134.17032 0.51846   1.000 29.17447  ? 147 PHE A CA  1 
ATOM   866  C  C   . PHE A 1 148 ? -56.16181 -133.46182 -0.15875  1.000 28.61949  ? 147 PHE A C   1 
ATOM   867  O  O   . PHE A 1 148 ? -56.34453 -132.66097 -1.08783  1.000 28.08122  ? 147 PHE A O   1 
ATOM   868  C  CB  . PHE A 1 148 ? -57.58844 -133.56391 1.90615   1.000 29.51503  ? 147 PHE A CB  1 
ATOM   869  C  CG  . PHE A 1 148 ? -58.98620 -133.78151 2.44458   1.000 31.37777  ? 147 PHE A CG  1 
ATOM   870  C  CD1 . PHE A 1 148 ? -59.89630 -134.60663 1.80129   1.000 28.28862  ? 147 PHE A CD1 1 
ATOM   871  C  CD2 . PHE A 1 148 ? -59.39293 -133.11715 3.60102   1.000 32.09499  ? 147 PHE A CD2 1 
ATOM   872  C  CE1 . PHE A 1 148 ? -61.18525 -134.77039 2.30874   1.000 36.26157  ? 147 PHE A CE1 1 
ATOM   873  C  CE2 . PHE A 1 148 ? -60.67894 -133.27771 4.10812   1.000 32.85108  ? 147 PHE A CE2 1 
ATOM   874  C  CZ  . PHE A 1 148 ? -61.56919 -134.10716 3.47398   1.000 32.56914  ? 147 PHE A CZ  1 
ATOM   875  N  N   . PHE A 1 149 ? -54.94015 -133.73887 0.30593   1.000 26.34442  ? 148 PHE A N   1 
ATOM   876  C  CA  . PHE A 1 149 ? -53.76841 -133.04401 -0.22932  1.000 27.57527  ? 148 PHE A CA  1 
ATOM   877  C  C   . PHE A 1 149 ? -53.58779 -133.35431 -1.71086  1.000 28.82632  ? 148 PHE A C   1 
ATOM   878  O  O   . PHE A 1 149 ? -53.29689 -132.46000 -2.51871  1.000 28.40475  ? 148 PHE A O   1 
ATOM   879  C  CB  . PHE A 1 149 ? -52.52513 -133.44402 0.57659   1.000 26.73541  ? 148 PHE A CB  1 
ATOM   880  C  CG  . PHE A 1 149 ? -51.30408 -132.57457 0.32371   1.000 26.36646  ? 148 PHE A CG  1 
ATOM   881  C  CD1 . PHE A 1 149 ? -51.32447 -131.21570 0.62057   1.000 26.04028  ? 148 PHE A CD1 1 
ATOM   882  C  CD2 . PHE A 1 149 ? -50.13175 -133.13166 -0.14981  1.000 27.09666  ? 148 PHE A CD2 1 
ATOM   883  C  CE1 . PHE A 1 149 ? -50.20334 -130.41892 0.42201   1.000 26.52862  ? 148 PHE A CE1 1 
ATOM   884  C  CE2 . PHE A 1 149 ? -49.00642 -132.34306 -0.37416  1.000 27.15936  ? 148 PHE A CE2 1 
ATOM   885  C  CZ  . PHE A 1 149 ? -49.03811 -130.98664 -0.07538  1.000 26.79904  ? 148 PHE A CZ  1 
ATOM   886  N  N   . TRP A 1 150 ? -53.78169 -134.61659 -2.08797  1.000 27.36146  ? 149 TRP A N   1 
ATOM   887  C  CA  . TRP A 1 150 ? -53.73030 -134.99526 -3.49478  1.000 26.28328  ? 149 TRP A CA  1 
ATOM   888  C  C   . TRP A 1 150 ? -54.69584 -134.16712 -4.32816  1.000 27.98420  ? 149 TRP A C   1 
ATOM   889  O  O   . TRP A 1 150 ? -54.32889 -133.63206 -5.38360  1.000 28.71641  ? 149 TRP A O   1 
ATOM   890  C  CB  . TRP A 1 150 ? -54.05508 -136.47829 -3.62550  1.000 24.49713  ? 149 TRP A CB  1 
ATOM   891  C  CG  . TRP A 1 150 ? -53.91616 -137.00369 -4.99160  1.000 28.40888  ? 149 TRP A CG  1 
ATOM   892  C  CD1 . TRP A 1 150 ? -54.91259 -137.13001 -5.93652  1.000 28.70940  ? 149 TRP A CD1 1 
ATOM   893  C  CD2 . TRP A 1 150 ? -52.71288 -137.48652 -5.60310  1.000 28.91945  ? 149 TRP A CD2 1 
ATOM   894  N  NE1 . TRP A 1 150 ? -54.39164 -137.66870 -7.09181  1.000 30.83747  ? 149 TRP A NE1 1 
ATOM   895  C  CE2 . TRP A 1 150 ? -53.05030 -137.90683 -6.91391  1.000 29.01179  ? 149 TRP A CE2 1 
ATOM   896  C  CE3 . TRP A 1 150 ? -51.38996 -137.64193 -5.15905  1.000 30.54996  ? 149 TRP A CE3 1 
ATOM   897  C  CZ2 . TRP A 1 150 ? -52.10439 -138.44700 -7.80090  1.000 33.32743  ? 149 TRP A CZ2 1 
ATOM   898  C  CZ3 . TRP A 1 150 ? -50.43967 -138.17604 -6.05204  1.000 30.24703  ? 149 TRP A CZ3 1 
ATOM   899  C  CH2 . TRP A 1 150 ? -50.81677 -138.58556 -7.35232  1.000 32.07509  ? 149 TRP A CH2 1 
ATOM   900  N  N   . GLN A 1 151 ? -55.95244 -134.06293 -3.88034  1.000 28.93505  ? 150 GLN A N   1 
ATOM   901  C  CA  . GLN A 1 151 ? -56.91895 -133.29674 -4.66321  1.000 28.47491  ? 150 GLN A CA  1 
ATOM   902  C  C   . GLN A 1 151 ? -56.52236 -131.83886 -4.74436  1.000 27.40781  ? 150 GLN A C   1 
ATOM   903  O  O   . GLN A 1 151 ? -56.76247 -131.18460 -5.76676  1.000 28.62976  ? 150 GLN A O   1 
ATOM   904  C  CB  . GLN A 1 151 ? -58.32515 -133.43405 -4.07362  1.000 29.58128  ? 150 GLN A CB  1 
ATOM   905  C  CG  . GLN A 1 151 ? -58.91112 -134.82516 -4.29442  1.000 29.71234  ? 150 GLN A CG  1 
ATOM   906  C  CD  . GLN A 1 151 ? -60.37439 -134.88315 -3.92084  1.000 39.16417  ? 150 GLN A CD  1 
ATOM   907  O  OE1 . GLN A 1 151 ? -61.11984 -133.92650 -4.13743  1.000 36.33831  ? 150 GLN A OE1 1 
ATOM   908  N  NE2 . GLN A 1 151 ? -60.78817 -135.99524 -3.33327  1.000 36.23871  ? 150 GLN A NE2 1 
ATOM   909  N  N   . VAL A 1 152 ? -55.91982 -131.30507 -3.68182  1.000 28.25749  ? 151 VAL A N   1 
ATOM   910  C  CA  . VAL A 1 152 ? -55.45850 -129.92538 -3.74818  1.000 27.93213  ? 151 VAL A CA  1 
ATOM   911  C  C   . VAL A 1 152 ? -54.31259 -129.80035 -4.74478  1.000 25.91507  ? 151 VAL A C   1 
ATOM   912  O  O   . VAL A 1 152 ? -54.25560 -128.84396 -5.52488  1.000 30.80710  ? 151 VAL A O   1 
ATOM   913  C  CB  . VAL A 1 152 ? -55.06582 -129.41816 -2.34877  1.000 27.58159  ? 151 VAL A CB  1 
ATOM   914  C  CG1 . VAL A 1 152 ? -54.42938 -128.02445 -2.45058  1.000 27.18262  ? 151 VAL A CG1 1 
ATOM   915  C  CG2 . VAL A 1 152 ? -56.31083 -129.35315 -1.45186  1.000 26.82514  ? 151 VAL A CG2 1 
ATOM   916  N  N   . LEU A 1 153 ? -53.38556 -130.75992 -4.74561  1.000 26.06110  ? 152 LEU A N   1 
ATOM   917  C  CA  . LEU A 1 153 ? -52.30859 -130.72623 -5.74286  1.000 25.11609  ? 152 LEU A CA  1 
ATOM   918  C  C   . LEU A 1 153 ? -52.86703 -130.74139 -7.16316  1.000 31.27365  ? 152 LEU A C   1 
ATOM   919  O  O   . LEU A 1 153 ? -52.44157 -129.96235 -8.02795  1.000 28.27939  ? 152 LEU A O   1 
ATOM   920  C  CB  . LEU A 1 153 ? -51.36641 -131.90995 -5.51910  1.000 29.06828  ? 152 LEU A CB  1 
ATOM   921  C  CG  . LEU A 1 153 ? -50.62294 -131.86964 -4.17862  1.000 32.64564  ? 152 LEU A CG  1 
ATOM   922  C  CD1 . LEU A 1 153 ? -49.95565 -133.20871 -3.92050  1.000 32.88238  ? 152 LEU A CD1 1 
ATOM   923  C  CD2 . LEU A 1 153 ? -49.60958 -130.75074 -4.14871  1.000 39.57732  ? 152 LEU A CD2 1 
ATOM   924  N  N   . GLU A 1 154 ? -53.81579 -131.63540 -7.42793  1.000 26.48768  ? 153 GLU A N   1 
ATOM   925  C  CA  . GLU A 1 154 ? -54.38388 -131.70549 -8.76874  1.000 29.79315  ? 153 GLU A CA  1 
ATOM   926  C  C   . GLU A 1 154 ? -55.07283 -130.39567 -9.14704  1.000 28.42821  ? 153 GLU A C   1 
ATOM   927  O  O   . GLU A 1 154 ? -54.97180 -129.95038 -10.29590 1.000 30.92212  ? 153 GLU A O   1 
ATOM   928  C  CB  . GLU A 1 154 ? -55.34103 -132.89600 -8.86064  1.000 30.33919  ? 153 GLU A CB  1 
ATOM   929  C  CG  . GLU A 1 154 ? -54.63212 -134.25290 -8.80383  1.000 32.95540  ? 153 GLU A CG  1 
ATOM   930  C  CD  . GLU A 1 154 ? -53.92437 -134.61543 -10.11665 1.000 33.90952  ? 153 GLU A CD  1 
ATOM   931  O  OE1 . GLU A 1 154 ? -54.51259 -134.38872 -11.19440 1.000 35.35128  ? 153 GLU A OE1 1 
ATOM   932  O  OE2 . GLU A 1 154 ? -52.78556 -135.12582 -10.06831 1.000 32.34810  ? 153 GLU A OE2 1 
ATOM   933  N  N   . ALA A 1 155 ? -55.75651 -129.74826 -8.18784  1.000 27.09110  ? 154 ALA A N   1 
ATOM   934  C  CA  . ALA A 1 155 ? -56.45228 -128.49254 -8.48335  1.000 29.66446  ? 154 ALA A CA  1 
ATOM   935  C  C   . ALA A 1 155 ? -55.47455 -127.34723 -8.72854  1.000 32.89660  ? 154 ALA A C   1 
ATOM   936  O  O   . ALA A 1 155 ? -55.70366 -126.49815 -9.60540  1.000 30.42053  ? 154 ALA A O   1 
ATOM   937  C  CB  . ALA A 1 155 ? -57.40892 -128.13527 -7.34307  1.000 27.03179  ? 154 ALA A CB  1 
ATOM   938  N  N   . VAL A 1 156 ? -54.39012 -127.28952 -7.95205  1.000 28.32109  ? 155 VAL A N   1 
ATOM   939  C  CA  . VAL A 1 156 ? -53.37515 -126.27333 -8.19284  1.000 31.09350  ? 155 VAL A CA  1 
ATOM   940  C  C   . VAL A 1 156 ? -52.66552 -126.52087 -9.52503  1.000 30.28181  ? 155 VAL A C   1 
ATOM   941  O  O   . VAL A 1 156 ? -52.35647 -125.57357 -10.26375 1.000 32.76636  ? 155 VAL A O   1 
ATOM   942  C  CB  . VAL A 1 156 ? -52.39355 -126.22900 -7.00605  1.000 33.22659  ? 155 VAL A CB  1 
ATOM   943  C  CG1 . VAL A 1 156 ? -51.22944 -125.29679 -7.30006  1.000 29.31057  ? 155 VAL A CG1 1 
ATOM   944  C  CG2 . VAL A 1 156 ? -53.13716 -125.78565 -5.74886  1.000 27.62209  ? 155 VAL A CG2 1 
ATOM   945  N  N   . ARG A 1 157 ? -52.38715 -127.78791 -9.85559  1.000 28.90072  ? 156 ARG A N   1 
ATOM   946  C  CA  . ARG A 1 157 ? -51.80736 -128.08219 -11.16667 1.000 29.94531  ? 156 ARG A CA  1 
ATOM   947  C  C   . ARG A 1 157 ? -52.73443 -127.61733 -12.28494 1.000 31.58711  ? 156 ARG A C   1 
ATOM   948  O  O   . ARG A 1 157 ? -52.27530 -127.08696 -13.30302 1.000 28.53775  ? 156 ARG A O   1 
ATOM   949  C  CB  . ARG A 1 157 ? -51.52096 -129.57914 -11.31266 1.000 27.67711  ? 156 ARG A CB  1 
ATOM   950  C  CG  . ARG A 1 157 ? -50.33109 -130.09383 -10.50430 1.000 30.01413  ? 156 ARG A CG  1 
ATOM   951  C  CD  . ARG A 1 157 ? -50.09745 -131.58176 -10.75639 1.000 32.52886  ? 156 ARG A CD  1 
ATOM   952  N  NE  . ARG A 1 157 ? -49.86106 -131.87149 -12.17297 1.000 29.51914  ? 156 ARG A NE  1 
ATOM   953  C  CZ  . ARG A 1 157 ? -50.03932 -133.05999 -12.73887 1.000 35.93834  ? 156 ARG A CZ  1 
ATOM   954  N  NH1 . ARG A 1 157 ? -50.44329 -134.11190 -12.03438 1.000 28.58612  ? 156 ARG A NH1 1 
ATOM   955  N  NH2 . ARG A 1 157 ? -49.81705 -133.19657 -14.04423 1.000 34.37903  ? 156 ARG A NH2 1 
ATOM   956  N  N   . HIS A 1 158 ? -54.04341 -127.82852 -12.11173 1.000 28.87964  ? 157 HIS A N   1 
ATOM   957  C  CA  . HIS A 1 158 ? -55.01896 -127.35136 -13.08416 1.000 32.44369  ? 157 HIS A CA  1 
ATOM   958  C  C   . HIS A 1 158 ? -54.90648 -125.84271 -13.26529 1.000 31.30096  ? 157 HIS A C   1 
ATOM   959  O  O   . HIS A 1 158 ? -54.85908 -125.34160 -14.39636 1.000 35.92581  ? 157 HIS A O   1 
ATOM   960  C  CB  . HIS A 1 158 ? -56.43330 -127.74482 -12.63494 1.000 32.06413  ? 157 HIS A CB  1 
ATOM   961  C  CG  . HIS A 1 158 ? -57.51596 -127.06196 -13.41139 1.000 36.47225  ? 157 HIS A CG  1 
ATOM   962  N  ND1 . HIS A 1 158 ? -57.90729 -127.47966 -14.66667 1.000 34.93205  ? 157 HIS A ND1 1 
ATOM   963  C  CD2 . HIS A 1 158 ? -58.27215 -125.97577 -13.12298 1.000 38.53696  ? 157 HIS A CD2 1 
ATOM   964  C  CE1 . HIS A 1 158 ? -58.86259 -126.68406 -15.11572 1.000 38.38784  ? 157 HIS A CE1 1 
ATOM   965  N  NE2 . HIS A 1 158 ? -59.10029 -125.76066 -14.20035 1.000 40.08421  ? 157 HIS A NE2 1 
ATOM   966  N  N   . CYS A 1 159 ? -54.86315 -125.09993 -12.15695 1.000 31.24279  ? 158 CYS A N   1 
ATOM   967  C  CA  . CYS A 1 159 ? -54.73496 -123.64385 -12.24060 1.000 33.80753  ? 158 CYS A CA  1 
ATOM   968  C  C   . CYS A 1 159 ? -53.48439 -123.24352 -13.00391 1.000 33.30798  ? 158 CYS A C   1 
ATOM   969  O  O   . CYS A 1 159 ? -53.53901 -122.40765 -13.91627 1.000 35.49495  ? 158 CYS A O   1 
ATOM   970  C  CB  . CYS A 1 159 ? -54.70417 -123.03060 -10.84580 1.000 27.87895  ? 158 CYS A CB  1 
ATOM   971  S  SG  . CYS A 1 159 ? -56.27527 -123.16447 -9.91991  1.000 33.68676  ? 158 CYS A SG  1 
ATOM   972  N  N   . HIS A 1 160 ? -52.33638 -123.81732 -12.62485 1.000 29.72916  ? 159 HIS A N   1 
ATOM   973  C  CA  . HIS A 1 160 ? -51.08821 -123.48946 -13.30108 1.000 31.08307  ? 159 HIS A CA  1 
ATOM   974  C  C   . HIS A 1 160 ? -51.15023 -123.83186 -14.78188 1.000 35.89028  ? 159 HIS A C   1 
ATOM   975  O  O   . HIS A 1 160 ? -50.67159 -123.05464 -15.62045 1.000 33.55736  ? 159 HIS A O   1 
ATOM   976  C  CB  . HIS A 1 160 ? -49.91658 -124.20631 -12.62072 1.000 32.63465  ? 159 HIS A CB  1 
ATOM   977  C  CG  . HIS A 1 160 ? -49.66667 -123.73126 -11.22223 1.000 37.41765  ? 159 HIS A CG  1 
ATOM   978  N  ND1 . HIS A 1 160 ? -48.67425 -124.25348 -10.41961 1.000 39.41306  ? 159 HIS A ND1 1 
ATOM   979  C  CD2 . HIS A 1 160 ? -50.30199 -122.79422 -10.47317 1.000 35.69666  ? 159 HIS A CD2 1 
ATOM   980  C  CE1 . HIS A 1 160 ? -48.69770 -123.64671 -9.24363  1.000 37.53750  ? 159 HIS A CE1 1 
ATOM   981  N  NE2 . HIS A 1 160 ? -49.67795 -122.75870 -9.24936  1.000 30.96144  ? 159 HIS A NE2 1 
ATOM   982  N  N   . ASN A 1 161 ? -51.73014 -124.99307 -15.12433 1.000 33.51781  ? 160 ASN A N   1 
ATOM   983  C  CA  . ASN A 1 161 ? -51.87193 -125.37396 -16.53033 1.000 33.28784  ? 160 ASN A CA  1 
ATOM   984  C  C   . ASN A 1 161 ? -52.74666 -124.38865 -17.29987 1.000 37.82437  ? 160 ASN A C   1 
ATOM   985  O  O   . ASN A 1 161 ? -52.57962 -124.23421 -18.51501 1.000 36.37847  ? 160 ASN A O   1 
ATOM   986  C  CB  . ASN A 1 161 ? -52.46471 -126.77961 -16.65575 1.000 37.25166  ? 160 ASN A CB  1 
ATOM   987  C  CG  . ASN A 1 161 ? -51.49824 -127.87834 -16.22131 1.000 46.45580  ? 160 ASN A CG  1 
ATOM   988  O  OD1 . ASN A 1 161 ? -50.27793 -127.74173 -16.33392 1.000 49.48803  ? 160 ASN A OD1 1 
ATOM   989  N  ND2 . ASN A 1 161 ? -52.05328 -128.99006 -15.74636 1.000 46.36991  ? 160 ASN A ND2 1 
ATOM   990  N  N   . CYS A 1 162 ? -53.69127 -123.74124 -16.62288 1.000 35.33347  ? 161 CYS A N   1 
ATOM   991  C  CA  . CYS A 1 162 ? -54.54056 -122.71201 -17.20884 1.000 37.16236  ? 161 CYS A CA  1 
ATOM   992  C  C   . CYS A 1 162 ? -53.91186 -121.31846 -17.17553 1.000 38.96775  ? 161 CYS A C   1 
ATOM   993  O  O   . CYS A 1 162 ? -54.56143 -120.36339 -17.60065 1.000 40.78077  ? 161 CYS A O   1 
ATOM   994  C  CB  . CYS A 1 162 ? -55.89831 -122.67198 -16.47443 1.000 35.76733  ? 161 CYS A CB  1 
ATOM   995  S  SG  . CYS A 1 162 ? -56.91601 -124.17389 -16.69929 1.000 40.86159  ? 161 CYS A SG  1 
ATOM   996  N  N   . GLY A 1 163 ? -52.69232 -121.16988 -16.65701 1.000 36.37575  ? 162 GLY A N   1 
ATOM   997  C  CA  . GLY A 1 163 ? -52.03346 -119.87512 -16.61394 1.000 37.35755  ? 162 GLY A CA  1 
ATOM   998  C  C   . GLY A 1 163 ? -52.34892 -119.03444 -15.39993 1.000 37.90807  ? 162 GLY A C   1 
ATOM   999  O  O   . GLY A 1 163 ? -52.18080 -117.80744 -15.44806 1.000 35.51353  ? 162 GLY A O   1 
ATOM   1000 N  N   . VAL A 1 164 ? -52.78261 -119.65068 -14.30127 1.000 34.00161  ? 163 VAL A N   1 
ATOM   1001 C  CA  . VAL A 1 164 ? -53.29077 -118.94200 -13.13335 1.000 32.08407  ? 163 VAL A CA  1 
ATOM   1002 C  C   . VAL A 1 164 ? -52.51272 -119.36877 -11.89173 1.000 32.26958  ? 163 VAL A C   1 
ATOM   1003 O  O   . VAL A 1 164 ? -52.36725 -120.56768 -11.62110 1.000 34.09919  ? 163 VAL A O   1 
ATOM   1004 C  CB  . VAL A 1 164 ? -54.79173 -119.21319 -12.94133 1.000 34.86325  ? 163 VAL A CB  1 
ATOM   1005 C  CG1 . VAL A 1 164 ? -55.27998 -118.61749 -11.61622 1.000 33.23022  ? 163 VAL A CG1 1 
ATOM   1006 C  CG2 . VAL A 1 164 ? -55.56917 -118.66889 -14.14812 1.000 34.32194  ? 163 VAL A CG2 1 
ATOM   1007 N  N   . LEU A 1 165 ? -52.04244 -118.38832 -11.13046 1.000 33.85811  ? 164 LEU A N   1 
ATOM   1008 C  CA  . LEU A 1 165 ? -51.39803 -118.60486 -9.83562  1.000 32.77973  ? 164 LEU A CA  1 
ATOM   1009 C  C   . LEU A 1 165 ? -52.33749 -118.12327 -8.73395  1.000 29.61168  ? 164 LEU A C   1 
ATOM   1010 O  O   . LEU A 1 165 ? -52.69509 -116.94097 -8.70105  1.000 33.80198  ? 164 LEU A O   1 
ATOM   1011 C  CB  . LEU A 1 165 ? -50.06590 -117.84733 -9.77346  1.000 35.15794  ? 164 LEU A CB  1 
ATOM   1012 C  CG  . LEU A 1 165 ? -49.17886 -118.11816 -8.55509  1.000 34.68826  ? 164 LEU A CG  1 
ATOM   1013 C  CD1 . LEU A 1 165 ? -48.56929 -119.53563 -8.64221  1.000 31.50166  ? 164 LEU A CD1 1 
ATOM   1014 C  CD2 . LEU A 1 165 ? -48.07534 -117.05256 -8.44288  1.000 34.83753  ? 164 LEU A CD2 1 
ATOM   1015 N  N   . HIS A 1 166 ? -52.70785 -119.01772 -7.80729  1.000 29.12418  ? 165 HIS A N   1 
ATOM   1016 C  CA  . HIS A 1 166 ? -53.73276 -118.66638 -6.81872  1.000 29.99141  ? 165 HIS A CA  1 
ATOM   1017 C  C   . HIS A 1 166 ? -53.19921 -117.68965 -5.76760  1.000 34.54841  ? 165 HIS A C   1 
ATOM   1018 O  O   . HIS A 1 166 ? -53.87624 -116.71548 -5.41260  1.000 35.49347  ? 165 HIS A O   1 
ATOM   1019 C  CB  . HIS A 1 166 ? -54.27646 -119.95032 -6.17247  1.000 27.90311  ? 165 HIS A CB  1 
ATOM   1020 C  CG  . HIS A 1 166 ? -55.43151 -119.73871 -5.23606  1.000 28.79772  ? 165 HIS A CG  1 
ATOM   1021 N  ND1 . HIS A 1 166 ? -55.27490 -119.25119 -3.95590  1.000 29.67270  ? 165 HIS A ND1 1 
ATOM   1022 C  CD2 . HIS A 1 166 ? -56.75538 -120.00180 -5.37899  1.000 29.28739  ? 165 HIS A CD2 1 
ATOM   1023 C  CE1 . HIS A 1 166 ? -56.45363 -119.20484 -3.35695  1.000 31.41814  ? 165 HIS A CE1 1 
ATOM   1024 N  NE2 . HIS A 1 166 ? -57.36809 -119.66050 -4.19737  1.000 33.14014  ? 165 HIS A NE2 1 
ATOM   1025 N  N   . ARG A 1 167 ? -52.00064 -117.94594 -5.23851  1.000 30.70350  ? 166 ARG A N   1 
ATOM   1026 C  CA  . ARG A 1 167 ? -51.29752 -117.10799 -4.26099  1.000 29.15535  ? 166 ARG A CA  1 
ATOM   1027 C  C   . ARG A 1 167 ? -51.97689 -116.99760 -2.89063  1.000 31.76819  ? 166 ARG A C   1 
ATOM   1028 O  O   . ARG A 1 167 ? -51.55385 -116.17942 -2.07005  1.000 38.79954  ? 166 ARG A O   1 
ATOM   1029 C  CB  . ARG A 1 167 ? -51.04969 -115.69269 -4.81023  1.000 29.69321  ? 166 ARG A CB  1 
ATOM   1030 C  CG  . ARG A 1 167 ? -50.25672 -115.67792 -6.09614  1.000 29.96584  ? 166 ARG A CG  1 
ATOM   1031 C  CD  . ARG A 1 167 ? -49.48422 -114.35270 -6.33337  1.000 37.12208  ? 166 ARG A CD  1 
ATOM   1032 N  NE  . ARG A 1 167 ? -50.38587 -113.22276 -6.54273  1.000 38.05006  ? 166 ARG A NE  1 
ATOM   1033 C  CZ  . ARG A 1 167 ? -49.98868 -112.00045 -6.88006  1.000 39.93607  ? 166 ARG A CZ  1 
ATOM   1034 N  NH1 . ARG A 1 167 ? -48.70458 -111.69628 -6.99850  1.000 37.45146  ? 166 ARG A NH1 1 
ATOM   1035 N  NH2 . ARG A 1 167 ? -50.90166 -111.06709 -7.12118  1.000 39.09405  ? 166 ARG A NH2 1 
ATOM   1036 N  N   . ASP A 1 168 ? -52.99520 -117.80303 -2.59177  1.000 32.48168  ? 167 ASP A N   1 
ATOM   1037 C  CA  . ASP A 1 168 ? -53.59482 -117.76501 -1.25959  1.000 33.50064  ? 167 ASP A CA  1 
ATOM   1038 C  C   . ASP A 1 168 ? -54.12330 -119.14841 -0.88983  1.000 32.27292  ? 167 ASP A C   1 
ATOM   1039 O  O   . ASP A 1 168 ? -55.22741 -119.28667 -0.35233  1.000 33.67915  ? 167 ASP A O   1 
ATOM   1040 C  CB  . ASP A 1 168 ? -54.70577 -116.70278 -1.16720  1.000 33.09181  ? 167 ASP A CB  1 
ATOM   1041 C  CG  . ASP A 1 168 ? -55.04690 -116.30895 0.27570   1.000 37.20498  ? 167 ASP A CG  1 
ATOM   1042 O  OD1 . ASP A 1 168 ? -54.24548 -116.58758 1.20767   1.000 35.80010  ? 167 ASP A OD1 1 
ATOM   1043 O  OD2 . ASP A 1 168 ? -56.13222 -115.70694 0.47822   1.000 35.74501  ? 167 ASP A OD2 1 
ATOM   1044 N  N   . ILE A 1 169 ? -53.34254 -120.18582 -1.18692  1.000 29.14045  ? 168 ILE A N   1 
ATOM   1045 C  CA  . ILE A 1 169 ? -53.70467 -121.54864 -0.80255  1.000 31.91018  ? 168 ILE A CA  1 
ATOM   1046 C  C   . ILE A 1 169 ? -53.67235 -121.65284 0.71944   1.000 29.42228  ? 168 ILE A C   1 
ATOM   1047 O  O   . ILE A 1 169 ? -52.64888 -121.37172 1.35717   1.000 28.68030  ? 168 ILE A O   1 
ATOM   1048 C  CB  . ILE A 1 169 ? -52.75948 -122.57762 -1.44539  1.000 31.79430  ? 168 ILE A CB  1 
ATOM   1049 C  CG1 . ILE A 1 169 ? -52.77795 -122.46483 -2.97454  1.000 32.71290  ? 168 ILE A CG1 1 
ATOM   1050 C  CG2 . ILE A 1 169 ? -53.14400 -124.01461 -0.97788  1.000 30.13670  ? 168 ILE A CG2 1 
ATOM   1051 C  CD1 . ILE A 1 169 ? -51.58084 -123.16462 -3.68692  1.000 31.38684  ? 168 ILE A CD1 1 
ATOM   1052 N  N   . LYS A 1 170 ? -54.80915 -122.01650 1.31413   1.000 30.43470  ? 169 LYS A N   1 
ATOM   1053 C  CA  . LYS A 1 170 ? -54.90355 -122.25175 2.75179   1.000 31.78294  ? 169 LYS A CA  1 
ATOM   1054 C  C   . LYS A 1 170 ? -56.19095 -123.02068 2.99724   1.000 27.99316  ? 169 LYS A C   1 
ATOM   1055 O  O   . LYS A 1 170 ? -57.04374 -123.11017 2.11192   1.000 30.32208  ? 169 LYS A O   1 
ATOM   1056 C  CB  . LYS A 1 170 ? -54.88115 -120.93789 3.55446   1.000 33.00762  ? 169 LYS A CB  1 
ATOM   1057 C  CG  . LYS A 1 170 ? -55.92511 -119.89670 3.15252   1.000 33.46757  ? 169 LYS A CG  1 
ATOM   1058 C  CD  . LYS A 1 170 ? -55.90165 -118.69651 4.14846   1.000 30.71647  ? 169 LYS A CD  1 
ATOM   1059 C  CE  . LYS A 1 170 ? -56.84077 -117.55311 3.72116   1.000 33.54306  ? 169 LYS A CE  1 
ATOM   1060 N  NZ  . LYS A 1 170 ? -56.82527 -116.47710 4.75197   1.000 35.62000  ? 169 LYS A NZ  1 
ATOM   1061 N  N   . ASP A 1 171 ? -56.32856 -123.57838 4.20841   1.000 30.15457  ? 170 ASP A N   1 
ATOM   1062 C  CA  . ASP A 1 171 ? -57.51744 -124.38770 4.48605   1.000 31.25759  ? 170 ASP A CA  1 
ATOM   1063 C  C   . ASP A 1 171 ? -58.80549 -123.56044 4.39323   1.000 34.20977  ? 170 ASP A C   1 
ATOM   1064 O  O   . ASP A 1 171 ? -59.84682 -124.08785 3.99379   1.000 29.41442  ? 170 ASP A O   1 
ATOM   1065 C  CB  . ASP A 1 171 ? -57.40257 -125.10929 5.85330   1.000 30.09728  ? 170 ASP A CB  1 
ATOM   1066 C  CG  . ASP A 1 171 ? -57.10944 -124.17023 7.04634   1.000 33.16780  ? 170 ASP A CG  1 
ATOM   1067 O  OD1 . ASP A 1 171 ? -57.01056 -122.93957 6.90244   1.000 31.71556  ? 170 ASP A OD1 1 
ATOM   1068 O  OD2 . ASP A 1 171 ? -56.95616 -124.69719 8.16121   1.000 30.44633  ? 170 ASP A OD2 1 
ATOM   1069 N  N   . GLU A 1 172 ? -58.75626 -122.26441 4.72157   1.000 31.20820  ? 171 GLU A N   1 
ATOM   1070 C  CA  . GLU A 1 172 ? -59.95279 -121.42867 4.60332   1.000 35.66834  ? 171 GLU A CA  1 
ATOM   1071 C  C   . GLU A 1 172 ? -60.43959 -121.29958 3.16574   1.000 35.59961  ? 171 GLU A C   1 
ATOM   1072 O  O   . GLU A 1 172 ? -61.62801 -121.02561 2.94993   1.000 34.37246  ? 171 GLU A O   1 
ATOM   1073 C  CB  . GLU A 1 172 ? -59.70309 -120.01969 5.14547   1.000 32.60530  ? 171 GLU A CB  1 
ATOM   1074 C  CG  . GLU A 1 172 ? -59.11747 -119.93103 6.55349   1.000 31.08749  ? 171 GLU A CG  1 
ATOM   1075 C  CD  . GLU A 1 172 ? -58.96026 -118.47071 6.95817   1.000 41.10525  ? 171 GLU A CD  1 
ATOM   1076 O  OE1 . GLU A 1 172 ? -59.96813 -117.72563 6.89943   1.000 43.56978  ? 171 GLU A OE1 1 
ATOM   1077 O  OE2 . GLU A 1 172 ? -57.83324 -118.05629 7.29553   1.000 41.21623  ? 171 GLU A OE2 1 
ATOM   1078 N  N   . ASN A 1 173 ? -59.55347 -121.46988 2.17974   1.000 29.12056  ? 172 ASN A N   1 
ATOM   1079 C  CA  . ASN A 1 173 ? -59.90947 -121.31167 0.77292   1.000 32.03934  ? 172 ASN A CA  1 
ATOM   1080 C  C   . ASN A 1 173 ? -60.14309 -122.64228 0.06957   1.000 27.84417  ? 172 ASN A C   1 
ATOM   1081 O  O   . ASN A 1 173 ? -59.99209 -122.73239 -1.14624  1.000 30.72240  ? 172 ASN A O   1 
ATOM   1082 C  CB  . ASN A 1 173 ? -58.83992 -120.50107 0.04043   1.000 28.57465  ? 172 ASN A CB  1 
ATOM   1083 C  CG  . ASN A 1 173 ? -58.91873 -119.03728 0.39772   1.000 36.63664  ? 172 ASN A CG  1 
ATOM   1084 O  OD1 . ASN A 1 173 ? -59.95765 -118.58724 0.87682   1.000 33.47327  ? 172 ASN A OD1 1 
ATOM   1085 N  ND2 . ASN A 1 173 ? -57.83586 -118.29801 0.19894   1.000 34.02638  ? 172 ASN A ND2 1 
ATOM   1086 N  N   . ILE A 1 174 ? -60.53904 -123.66574 0.81400   1.000 31.99348  ? 173 ILE A N   1 
ATOM   1087 C  CA  . ILE A 1 174 ? -60.82149 -124.98464 0.27315   1.000 33.11692  ? 173 ILE A CA  1 
ATOM   1088 C  C   . ILE A 1 174 ? -62.17246 -125.41596 0.82531   1.000 32.67351  ? 173 ILE A C   1 
ATOM   1089 O  O   . ILE A 1 174 ? -62.35963 -125.44450 2.04791   1.000 32.13775  ? 173 ILE A O   1 
ATOM   1090 C  CB  . ILE A 1 174 ? -59.73336 -126.00897 0.65274   1.000 31.56430  ? 173 ILE A CB  1 
ATOM   1091 C  CG1 . ILE A 1 174 ? -58.40696 -125.65603 -0.03004  1.000 32.89238  ? 173 ILE A CG1 1 
ATOM   1092 C  CG2 . ILE A 1 174 ? -60.18264 -127.42073 0.27973   1.000 31.70582  ? 173 ILE A CG2 1 
ATOM   1093 C  CD1 . ILE A 1 174 ? -57.20168 -126.31719 0.60715   1.000 32.92158  ? 173 ILE A CD1 1 
ATOM   1094 N  N   . LEU A 1 175 ? -63.09908 -125.76174 -0.06843  1.000 31.69068  ? 174 LEU A N   1 
ATOM   1095 C  CA  . LEU A 1 175 ? -64.40761 -126.28393 0.30276   1.000 33.45065  ? 174 LEU A CA  1 
ATOM   1096 C  C   . LEU A 1 175 ? -64.39857 -127.79398 0.12712   1.000 33.46597  ? 174 LEU A C   1 
ATOM   1097 O  O   . LEU A 1 175 ? -63.82791 -128.30724 -0.83770  1.000 35.24181  ? 174 LEU A O   1 
ATOM   1098 C  CB  . LEU A 1 175 ? -65.52485 -125.67869 -0.56019  1.000 35.57740  ? 174 LEU A CB  1 
ATOM   1099 C  CG  . LEU A 1 175 ? -65.76187 -124.15907 -0.56667  1.000 37.92374  ? 174 LEU A CG  1 
ATOM   1100 C  CD1 . LEU A 1 175 ? -66.95113 -123.80977 -1.48501  1.000 33.80563  ? 174 LEU A CD1 1 
ATOM   1101 C  CD2 . LEU A 1 175 ? -66.02037 -123.61184 0.82882   1.000 38.82621  ? 174 LEU A CD2 1 
ATOM   1102 N  N   . ILE A 1 176 ? -65.02661 -128.49986 1.06065   1.000 36.32686  ? 175 ILE A N   1 
ATOM   1103 C  CA  . ILE A 1 176 ? -65.21652 -129.94313 0.95628   1.000 37.59317  ? 175 ILE A CA  1 
ATOM   1104 C  C   . ILE A 1 176 ? -66.66471 -130.21091 0.57303   1.000 37.52799  ? 175 ILE A C   1 
ATOM   1105 O  O   . ILE A 1 176 ? -67.57918 -129.87562 1.33295   1.000 37.22942  ? 175 ILE A O   1 
ATOM   1106 C  CB  . ILE A 1 176 ? -64.89152 -130.65820 2.27605   1.000 33.57912  ? 175 ILE A CB  1 
ATOM   1107 C  CG1 . ILE A 1 176 ? -63.50822 -130.24442 2.80189   1.000 29.99924  ? 175 ILE A CG1 1 
ATOM   1108 C  CG2 . ILE A 1 176 ? -65.04111 -132.17410 2.08867   1.000 34.72899  ? 175 ILE A CG2 1 
ATOM   1109 C  CD1 . ILE A 1 176 ? -63.33745 -130.55018 4.29271   1.000 33.67339  ? 175 ILE A CD1 1 
ATOM   1110 N  N   . ASP A 1 177 ? -66.87642 -130.83510 -0.58102  1.000 34.28585  ? 176 ASP A N   1 
ATOM   1111 C  CA  . ASP A 1 177 ? -68.17640 -131.42242 -0.89447  1.000 40.52198  ? 176 ASP A CA  1 
ATOM   1112 C  C   . ASP A 1 177 ? -68.31550 -132.69393 -0.06402  1.000 45.37881  ? 176 ASP A C   1 
ATOM   1113 O  O   . ASP A 1 177 ? -67.73307 -133.73076 -0.39020  1.000 42.44687  ? 176 ASP A O   1 
ATOM   1114 C  CB  . ASP A 1 177 ? -68.29692 -131.70322 -2.38827  1.000 36.15627  ? 176 ASP A CB  1 
ATOM   1115 C  CG  . ASP A 1 177 ? -69.66199 -132.28413 -2.77321  1.000 40.60920  ? 176 ASP A CG  1 
ATOM   1116 O  OD1 . ASP A 1 177 ? -70.28628 -132.99994 -1.96145  1.000 49.38542  ? 176 ASP A OD1 1 
ATOM   1117 O  OD2 . ASP A 1 177 ? -70.10328 -132.02890 -3.89797  1.000 47.80964  ? 176 ASP A OD2 1 
ATOM   1118 N  N   . LEU A 1 178 ? -69.10252 -132.61673 1.01366   1.000 41.60350  ? 177 LEU A N   1 
ATOM   1119 C  CA  . LEU A 1 178 ? -69.15312 -133.71021 1.97714   1.000 42.05635  ? 177 LEU A CA  1 
ATOM   1120 C  C   . LEU A 1 178 ? -69.76543 -134.97505 1.38774   1.000 49.74267  ? 177 LEU A C   1 
ATOM   1121 O  O   . LEU A 1 178 ? -69.43926 -136.08070 1.83635   1.000 55.85504  ? 177 LEU A O   1 
ATOM   1122 C  CB  . LEU A 1 178 ? -69.92994 -133.27516 3.22367   1.000 44.77724  ? 177 LEU A CB  1 
ATOM   1123 C  CG  . LEU A 1 178 ? -69.28009 -132.17006 4.06173   1.000 42.38830  ? 177 LEU A CG  1 
ATOM   1124 C  CD1 . LEU A 1 178 ? -70.25129 -131.66106 5.11293   1.000 45.60405  ? 177 LEU A CD1 1 
ATOM   1125 C  CD2 . LEU A 1 178 ? -68.00139 -132.68555 4.71986   1.000 39.30575  ? 177 LEU A CD2 1 
ATOM   1126 N  N   . ASN A 1 179 ? -70.65870 -134.84762 0.40697   1.000 47.82421  ? 178 ASN A N   1 
ATOM   1127 C  CA  . ASN A 1 179 ? -71.31162 -136.03899 -0.13291  1.000 47.13892  ? 178 ASN A CA  1 
ATOM   1128 C  C   . ASN A 1 179 ? -70.46187 -136.70835 -1.20467  1.000 49.67170  ? 178 ASN A C   1 
ATOM   1129 O  O   . ASN A 1 179 ? -70.45849 -137.93849 -1.31923  1.000 44.82663  ? 178 ASN A O   1 
ATOM   1130 C  CB  . ASN A 1 179 ? -72.68644 -135.68553 -0.70204  1.000 52.12829  ? 178 ASN A CB  1 
ATOM   1131 C  CG  . ASN A 1 179 ? -73.80062 -135.83886 0.31984   1.000 57.54125  ? 178 ASN A CG  1 
ATOM   1132 O  OD1 . ASN A 1 179 ? -73.54041 -136.08236 1.50171   1.000 62.31251  ? 178 ASN A OD1 1 
ATOM   1133 N  N   . ARG A 1 180 ? -69.73325 -135.92207 -1.99472  1.000 41.71337  ? 179 ARG A N   1 
ATOM   1134 C  CA  . ARG A 1 180 ? -68.92327 -136.47037 -3.07188  1.000 41.91830  ? 179 ARG A CA  1 
ATOM   1135 C  C   . ARG A 1 180 ? -67.45861 -136.66146 -2.68943  1.000 42.50062  ? 179 ARG A C   1 
ATOM   1136 O  O   . ARG A 1 180 ? -66.73113 -137.33548 -3.42412  1.000 36.42705  ? 179 ARG A O   1 
ATOM   1137 C  CB  . ARG A 1 180 ? -69.03114 -135.57412 -4.31530  1.000 45.11350  ? 179 ARG A CB  1 
ATOM   1138 C  CG  . ARG A 1 180 ? -70.47828 -135.48238 -4.84706  1.000 55.44828  ? 179 ARG A CG  1 
ATOM   1139 C  CD  . ARG A 1 180 ? -70.61207 -134.55390 -6.04126  1.000 50.65050  ? 179 ARG A CD  1 
ATOM   1140 N  NE  . ARG A 1 180 ? -69.61254 -134.84255 -7.05992  1.000 51.84663  ? 179 ARG A NE  1 
ATOM   1141 C  CZ  . ARG A 1 180 ? -69.77928 -135.70425 -8.05412  1.000 62.59344  ? 179 ARG A CZ  1 
ATOM   1142 N  NH1 . ARG A 1 180 ? -70.91102 -136.37276 -8.20700  1.000 60.51134  ? 179 ARG A NH1 1 
ATOM   1143 N  NH2 . ARG A 1 180 ? -68.78183 -135.90499 -8.91218  1.000 62.36720  ? 179 ARG A NH2 1 
ATOM   1144 N  N   . GLY A 1 181 ? -67.01978 -136.12556 -1.55201  1.000 38.62895  ? 180 GLY A N   1 
ATOM   1145 C  CA  . GLY A 1 181 ? -65.62437 -136.24575 -1.16573  1.000 38.89078  ? 180 GLY A CA  1 
ATOM   1146 C  C   . GLY A 1 181 ? -64.68210 -135.47558 -2.07376  1.000 43.97179  ? 180 GLY A C   1 
ATOM   1147 O  O   . GLY A 1 181 ? -63.52994 -135.88615 -2.25905  1.000 40.36668  ? 180 GLY A O   1 
ATOM   1148 N  N   . GLU A 1 182 ? -65.15596 -134.38081 -2.66692  1.000 36.29768  ? 181 GLU A N   1 
ATOM   1149 C  CA  . GLU A 1 182 ? -64.38489 -133.57207 -3.60376  1.000 36.93264  ? 181 GLU A CA  1 
ATOM   1150 C  C   . GLU A 1 182 ? -64.06986 -132.22824 -2.97272  1.000 36.72894  ? 181 GLU A C   1 
ATOM   1151 O  O   . GLU A 1 182 ? -64.94895 -131.59143 -2.37837  1.000 38.71215  ? 181 GLU A O   1 
ATOM   1152 C  CB  . GLU A 1 182 ? -65.15029 -133.33235 -4.90823  1.000 36.78076  ? 181 GLU A CB  1 
ATOM   1153 C  CG  . GLU A 1 182 ? -65.39164 -134.55802 -5.74735  1.000 42.48968  ? 181 GLU A CG  1 
ATOM   1154 C  CD  . GLU A 1 182 ? -66.37747 -134.28849 -6.87752  1.000 50.95409  ? 181 GLU A CD  1 
ATOM   1155 O  OE1 . GLU A 1 182 ? -67.03542 -133.22363 -6.86084  1.000 52.53194  ? 181 GLU A OE1 1 
ATOM   1156 O  OE2 . GLU A 1 182 ? -66.49817 -135.14256 -7.77300  1.000 52.70290  ? 181 GLU A OE2 1 
ATOM   1157 N  N   . LEU A 1 183 ? -62.82095 -131.79715 -3.11578  1.000 32.88383  ? 182 LEU A N   1 
ATOM   1158 C  CA  . LEU A 1 183 ? -62.36854 -130.50890 -2.60831  1.000 30.47357  ? 182 LEU A CA  1 
ATOM   1159 C  C   . LEU A 1 183 ? -62.37087 -129.48034 -3.73117  1.000 30.31251  ? 182 LEU A C   1 
ATOM   1160 O  O   . LEU A 1 183 ? -62.04520 -129.80260 -4.87699  1.000 32.02682  ? 182 LEU A O   1 
ATOM   1161 C  CB  . LEU A 1 183 ? -60.96400 -130.61580 -2.00478  1.000 31.70424  ? 182 LEU A CB  1 
ATOM   1162 C  CG  . LEU A 1 183 ? -60.91677 -130.99004 -0.51435  1.000 35.54561  ? 182 LEU A CG  1 
ATOM   1163 C  CD1 . LEU A 1 183 ? -61.71427 -132.26391 -0.23333  1.000 36.22096  ? 182 LEU A CD1 1 
ATOM   1164 C  CD2 . LEU A 1 183 ? -59.45662 -131.14658 -0.06269  1.000 33.82268  ? 182 LEU A CD2 1 
ATOM   1165 N  N   . LYS A 1 184 ? -62.73747 -128.24068 -3.39439  1.000 31.84356  ? 183 LYS A N   1 
ATOM   1166 C  CA  . LYS A 1 184 ? -62.86451 -127.16740 -4.37475  1.000 33.09192  ? 183 LYS A CA  1 
ATOM   1167 C  C   . LYS A 1 184 ? -62.12638 -125.93358 -3.87444  1.000 29.29050  ? 183 LYS A C   1 
ATOM   1168 O  O   . LYS A 1 184 ? -62.41443 -125.44726 -2.78038  1.000 32.17056  ? 183 LYS A O   1 
ATOM   1169 C  CB  . LYS A 1 184 ? -64.34558 -126.81251 -4.62699  1.000 33.69487  ? 183 LYS A CB  1 
ATOM   1170 C  CG  . LYS A 1 184 ? -65.23237 -127.97063 -5.09460  1.000 37.74458  ? 183 LYS A CG  1 
ATOM   1171 C  CD  . LYS A 1 184 ? -64.96256 -128.32001 -6.54971  1.000 39.24952  ? 183 LYS A CD  1 
ATOM   1172 C  CE  . LYS A 1 184 ? -66.02297 -129.31096 -7.09082  1.000 38.88824  ? 183 LYS A CE  1 
ATOM   1173 N  NZ  . LYS A 1 184 ? -65.60131 -129.84105 -8.40009  1.000 45.57012  ? 183 LYS A NZ  1 
ATOM   1174 N  N   . LEU A 1 185 ? -61.22045 -125.40589 -4.69812  1.000 32.42164  ? 184 LEU A N   1 
ATOM   1175 C  CA  . LEU A 1 185 ? -60.50460 -124.17154 -4.39275  1.000 28.83869  ? 184 LEU A CA  1 
ATOM   1176 C  C   . LEU A 1 185 ? -61.38445 -122.94442 -4.61828  1.000 34.61301  ? 184 LEU A C   1 
ATOM   1177 O  O   . LEU A 1 185 ? -62.11136 -122.86243 -5.61274  1.000 34.10723  ? 184 LEU A O   1 
ATOM   1178 C  CB  . LEU A 1 185 ? -59.27771 -124.05463 -5.29721  1.000 27.63031  ? 184 LEU A CB  1 
ATOM   1179 C  CG  . LEU A 1 185 ? -57.87158 -124.37894 -4.83648  1.000 43.81385  ? 184 LEU A CG  1 
ATOM   1180 C  CD1 . LEU A 1 185 ? -56.90640 -123.99711 -5.96423  1.000 38.63555  ? 184 LEU A CD1 1 
ATOM   1181 C  CD2 . LEU A 1 185 ? -57.53190 -123.65843 -3.50893  1.000 42.52859  ? 184 LEU A CD2 1 
ATOM   1182 N  N   . ILE A 1 186 ? -61.28158 -121.96308 -3.71993  1.000 33.74094  ? 185 ILE A N   1 
ATOM   1183 C  CA  . ILE A 1 186 ? -62.03760 -120.72391 -3.84308  1.000 34.81445  ? 185 ILE A CA  1 
ATOM   1184 C  C   . ILE A 1 186 ? -61.11675 -119.52523 -3.64438  1.000 36.23538  ? 185 ILE A C   1 
ATOM   1185 O  O   . ILE A 1 186 ? -59.98899 -119.63821 -3.16167  1.000 33.24791  ? 185 ILE A O   1 
ATOM   1186 C  CB  . ILE A 1 186 ? -63.21677 -120.63939 -2.84508  1.000 33.77140  ? 185 ILE A CB  1 
ATOM   1187 C  CG1 . ILE A 1 186 ? -62.72231 -120.70352 -1.39378  1.000 32.21505  ? 185 ILE A CG1 1 
ATOM   1188 C  CG2 . ILE A 1 186 ? -64.21620 -121.73647 -3.11508  1.000 36.35015  ? 185 ILE A CG2 1 
ATOM   1189 C  CD1 . ILE A 1 186 ? -63.80925 -120.36655 -0.36858  1.000 35.50095  ? 185 ILE A CD1 1 
ATOM   1190 N  N   . ASP A 1 187 ? -61.65163 -118.36101 -4.00979  1.000 30.99790  ? 186 ASP A N   1 
ATOM   1191 C  CA  . ASP A 1 187 ? -61.10798 -117.04096 -3.72396  1.000 34.36006  ? 186 ASP A CA  1 
ATOM   1192 C  C   . ASP A 1 187 ? -59.78278 -116.77525 -4.42244  1.000 33.84656  ? 186 ASP A C   1 
ATOM   1193 O  O   . ASP A 1 187 ? -58.70963 -116.87656 -3.81518  1.000 31.43174  ? 186 ASP A O   1 
ATOM   1194 C  CB  . ASP A 1 187 ? -60.96777 -116.81593 -2.21922  1.000 34.09020  ? 186 ASP A CB  1 
ATOM   1195 C  CG  . ASP A 1 187 ? -60.89559 -115.32181 -1.86360  1.000 46.08261  ? 186 ASP A CG  1 
ATOM   1196 O  OD1 . ASP A 1 187 ? -60.70029 -114.49779 -2.79465  1.000 43.38244  ? 186 ASP A OD1 1 
ATOM   1197 O  OD2 . ASP A 1 187 ? -61.04972 -114.97318 -0.66970  1.000 47.51328  ? 186 ASP A OD2 1 
ATOM   1198 N  N   . PHE A 1 188 ? -59.87368 -116.37442 -5.69119  1.000 31.02635  ? 187 PHE A N   1 
ATOM   1199 C  CA  . PHE A 1 188 ? -58.74030 -115.95579 -6.49747  1.000 35.92222  ? 187 PHE A CA  1 
ATOM   1200 C  C   . PHE A 1 188 ? -58.46766 -114.45636 -6.38127  1.000 39.12216  ? 187 PHE A C   1 
ATOM   1201 O  O   . PHE A 1 188 ? -57.73396 -113.90225 -7.20840  1.000 39.71821  ? 187 PHE A O   1 
ATOM   1202 C  CB  . PHE A 1 188 ? -58.97152 -116.36725 -7.95943  1.000 34.63128  ? 187 PHE A CB  1 
ATOM   1203 C  CG  . PHE A 1 188 ? -58.87973 -117.85361 -8.18254  1.000 37.48864  ? 187 PHE A CG  1 
ATOM   1204 C  CD1 . PHE A 1 188 ? -59.94671 -118.68820 -7.86635  1.000 38.46007  ? 187 PHE A CD1 1 
ATOM   1205 C  CD2 . PHE A 1 188 ? -57.71461 -118.42679 -8.68074  1.000 32.93613  ? 187 PHE A CD2 1 
ATOM   1206 C  CE1 . PHE A 1 188 ? -59.85580 -120.07058 -8.03702  1.000 35.86319  ? 187 PHE A CE1 1 
ATOM   1207 C  CE2 . PHE A 1 188 ? -57.61720 -119.80777 -8.85983  1.000 31.66268  ? 187 PHE A CE2 1 
ATOM   1208 C  CZ  . PHE A 1 188 ? -58.68813 -120.63108 -8.54152  1.000 36.25783  ? 187 PHE A CZ  1 
ATOM   1209 N  N   . GLY A 1 189 ? -59.02597 -113.80129 -5.36036  1.000 38.75073  ? 188 GLY A N   1 
ATOM   1210 C  CA  . GLY A 1 189 ? -58.89566 -112.36782 -5.15548  1.000 42.89554  ? 188 GLY A CA  1 
ATOM   1211 C  C   . GLY A 1 189 ? -57.48046 -111.88160 -4.90818  1.000 48.90827  ? 188 GLY A C   1 
ATOM   1212 O  O   . GLY A 1 189 ? -57.23650 -110.67648 -5.02251  1.000 42.99927  ? 188 GLY A O   1 
ATOM   1213 N  N   . SER A 1 190 ? -56.55226 -112.77453 -4.56882  1.000 36.78561  ? 189 SER A N   1 
ATOM   1214 C  CA  . SER A 1 190 ? -55.14713 -112.42108 -4.42419  1.000 39.73043  ? 189 SER A CA  1 
ATOM   1215 C  C   . SER A 1 190 ? -54.28613 -113.06165 -5.50230  1.000 35.29115  ? 189 SER A C   1 
ATOM   1216 O  O   . SER A 1 190 ? -53.05866 -113.04943 -5.39156  1.000 37.26671  ? 189 SER A O   1 
ATOM   1217 C  CB  . SER A 1 190 ? -54.63509 -112.82405 -3.03774  1.000 42.22899  ? 189 SER A CB  1 
ATOM   1218 O  OG  . SER A 1 190 ? -55.38500 -112.20001 -2.00677  1.000 47.22090  ? 189 SER A OG  1 
ATOM   1219 N  N   . GLY A 1 191 ? -54.90037 -113.62128 -6.53916  1.000 33.82003  ? 190 GLY A N   1 
ATOM   1220 C  CA  . GLY A 1 191 ? -54.17464 -114.35450 -7.54582  1.000 34.00637  ? 190 GLY A CA  1 
ATOM   1221 C  C   . GLY A 1 191 ? -53.46411 -113.45233 -8.53973  1.000 39.64729  ? 190 GLY A C   1 
ATOM   1222 O  O   . GLY A 1 191 ? -53.43133 -112.22849 -8.42164  1.000 37.50165  ? 190 GLY A O   1 
ATOM   1223 N  N   . ALA A 1 192 ? -52.88375 -114.09574 -9.54515  1.000 34.72860  ? 191 ALA A N   1 
ATOM   1224 C  CA  . ALA A 1 192 ? -52.16937 -113.40759 -10.61364 1.000 38.12066  ? 191 ALA A CA  1 
ATOM   1225 C  C   . ALA A 1 192 ? -52.05380 -114.35997 -11.78974 1.000 39.98364  ? 191 ALA A C   1 
ATOM   1226 O  O   . ALA A 1 192 ? -52.15035 -115.57814 -11.62525 1.000 36.39724  ? 191 ALA A O   1 
ATOM   1227 C  CB  . ALA A 1 192 ? -50.77842 -112.94937 -10.15477 1.000 34.24920  ? 191 ALA A CB  1 
ATOM   1228 N  N   . LEU A 1 193 ? -51.85575 -113.79339 -12.98739 1.000 35.36781  ? 192 LEU A N   1 
ATOM   1229 C  CA  . LEU A 1 193 ? -51.46824 -114.62627 -14.11281 1.000 33.06546  ? 192 LEU A CA  1 
ATOM   1230 C  C   . LEU A 1 193 ? -50.16891 -115.33316 -13.75558 1.000 35.95252  ? 192 LEU A C   1 
ATOM   1231 O  O   . LEU A 1 193 ? -49.28804 -114.75386 -13.11508 1.000 36.70356  ? 192 LEU A O   1 
ATOM   1232 C  CB  . LEU A 1 193 ? -51.29742 -113.78288 -15.38656 1.000 38.29473  ? 192 LEU A CB  1 
ATOM   1233 C  CG  . LEU A 1 193 ? -52.54600 -113.03511 -15.89589 1.000 43.89555  ? 192 LEU A CG  1 
ATOM   1234 C  CD1 . LEU A 1 193 ? -52.19211 -112.14287 -17.08562 1.000 40.86111  ? 192 LEU A CD1 1 
ATOM   1235 C  CD2 . LEU A 1 193 ? -53.63503 -114.02292 -16.29076 1.000 40.76474  ? 192 LEU A CD2 1 
ATOM   1236 N  N   . LEU A 1 194 ? -50.05943 -116.60056 -14.13365 1.000 36.12510  ? 193 LEU A N   1 
ATOM   1237 C  CA  . LEU A 1 194 ? -48.82998 -117.32975 -13.85791 1.000 34.71657  ? 193 LEU A CA  1 
ATOM   1238 C  C   . LEU A 1 194 ? -47.71627 -116.84012 -14.77968 1.000 38.70545  ? 193 LEU A C   1 
ATOM   1239 O  O   . LEU A 1 194 ? -47.89058 -116.77219 -15.99978 1.000 39.19177  ? 193 LEU A O   1 
ATOM   1240 C  CB  . LEU A 1 194 ? -49.04642 -118.82793 -14.04972 1.000 37.10609  ? 193 LEU A CB  1 
ATOM   1241 C  CG  . LEU A 1 194 ? -47.80455 -119.70163 -13.85206 1.000 39.66940  ? 193 LEU A CG  1 
ATOM   1242 C  CD1 . LEU A 1 194 ? -47.28518 -119.55816 -12.43676 1.000 37.84722  ? 193 LEU A CD1 1 
ATOM   1243 C  CD2 . LEU A 1 194 ? -48.11735 -121.16320 -14.15907 1.000 42.13858  ? 193 LEU A CD2 1 
ATOM   1244 N  N   . LYS A 1 195 ? -46.56683 -116.50890 -14.20303 1.000 37.53147  ? 194 LYS A N   1 
ATOM   1245 C  CA  . LYS A 1 195 ? -45.39982 -116.14271 -14.99804 1.000 40.97048  ? 194 LYS A CA  1 
ATOM   1246 C  C   . LYS A 1 195 ? -44.18854 -116.85420 -14.41907 1.000 40.71067  ? 194 LYS A C   1 
ATOM   1247 O  O   . LYS A 1 195 ? -44.20464 -117.30704 -13.27157 1.000 38.34568  ? 194 LYS A O   1 
ATOM   1248 C  CB  . LYS A 1 195 ? -45.16908 -114.62638 -15.00436 1.000 40.54407  ? 194 LYS A CB  1 
ATOM   1249 C  CG  . LYS A 1 195 ? -44.76185 -114.09182 -13.62372 1.000 41.58667  ? 194 LYS A CG  1 
ATOM   1250 C  CD  . LYS A 1 195 ? -44.73618 -112.57034 -13.59197 1.000 46.94223  ? 194 LYS A CD  1 
ATOM   1251 C  CE  . LYS A 1 195 ? -44.16956 -112.05936 -12.26863 1.000 39.34309  ? 194 LYS A CE  1 
ATOM   1252 N  NZ  . LYS A 1 195 ? -44.25659 -110.57345 -12.20821 1.000 40.73492  ? 194 LYS A NZ  1 
ATOM   1253 N  N   . ASP A 1 196 ? -43.13026 -116.94419 -15.22659 1.000 41.13861  ? 195 ASP A N   1 
ATOM   1254 C  CA  . ASP A 1 196 ? -41.89061 -117.57349 -14.79745 1.000 37.04281  ? 195 ASP A CA  1 
ATOM   1255 C  C   . ASP A 1 196 ? -40.88904 -116.57618 -14.22997 1.000 45.22755  ? 195 ASP A C   1 
ATOM   1256 O  O   . ASP A 1 196 ? -39.84300 -116.99542 -13.71507 1.000 41.65104  ? 195 ASP A O   1 
ATOM   1257 C  CB  . ASP A 1 196 ? -41.25464 -118.32764 -15.96737 1.000 44.35424  ? 195 ASP A CB  1 
ATOM   1258 C  CG  . ASP A 1 196 ? -42.11531 -119.48128 -16.46219 1.000 45.48655  ? 195 ASP A CG  1 
ATOM   1259 O  OD1 . ASP A 1 196 ? -42.59851 -120.26231 -15.62818 1.000 47.41163  ? 195 ASP A OD1 1 
ATOM   1260 O  OD2 . ASP A 1 196 ? -42.29209 -119.61679 -17.69426 1.000 54.97007  ? 195 ASP A OD2 1 
ATOM   1261 N  N   . THR A 1 197 ? -41.18120 -115.27638 -14.31447 1.000 44.15788  ? 196 THR A N   1 
ATOM   1262 C  CA  . THR A 1 197 ? -40.32813 -114.22786 -13.77246 1.000 43.38348  ? 196 THR A CA  1 
ATOM   1263 C  C   . THR A 1 197 ? -40.69579 -113.95717 -12.31227 1.000 42.81625  ? 196 THR A C   1 
ATOM   1264 O  O   . THR A 1 197 ? -41.63773 -114.53389 -11.76370 1.000 37.31950  ? 196 THR A O   1 
ATOM   1265 C  CB  . THR A 1 197 ? -40.44179 -112.96070 -14.62653 1.000 41.60222  ? 196 THR A CB  1 
ATOM   1266 O  OG1 . THR A 1 197 ? -41.82003 -112.69730 -14.89263 1.000 41.45082  ? 196 THR A OG1 1 
ATOM   1267 C  CG2 . THR A 1 197 ? -39.73165 -113.15371 -15.94512 1.000 43.51358  ? 196 THR A CG2 1 
ATOM   1268 N  N   . VAL A 1 198 ? -39.94998 -113.07173 -11.66396 1.000 39.99734  ? 197 VAL A N   1 
ATOM   1269 C  CA  . VAL A 1 198 ? -40.08434 -112.90090 -10.22112 1.000 39.61436  ? 197 VAL A CA  1 
ATOM   1270 C  C   . VAL A 1 198 ? -41.31533 -112.06028 -9.90353  1.000 42.78337  ? 197 VAL A C   1 
ATOM   1271 O  O   . VAL A 1 198 ? -41.66453 -111.12331 -10.64055 1.000 41.27104  ? 197 VAL A O   1 
ATOM   1272 C  CB  . VAL A 1 198 ? -38.80751 -112.27286 -9.62664  1.000 42.79033  ? 197 VAL A CB  1 
ATOM   1273 C  CG1 . VAL A 1 198 ? -38.68764 -110.79337 -10.00842 1.000 47.11992  ? 197 VAL A CG1 1 
ATOM   1274 C  CG2 . VAL A 1 198 ? -38.78900 -112.43715 -8.11196  1.000 45.13879  ? 197 VAL A CG2 1 
ATOM   1275 N  N   . TYR A 1 199 ? -41.97775 -112.39393 -8.79493  1.000 41.05307  ? 198 TYR A N   1 
ATOM   1276 C  CA  . TYR A 1 199 ? -43.06146 -111.58824 -8.23972  1.000 39.34183  ? 198 TYR A CA  1 
ATOM   1277 C  C   . TYR A 1 199 ? -42.52940 -110.69338 -7.12463  1.000 40.16041  ? 198 TYR A C   1 
ATOM   1278 O  O   . TYR A 1 199 ? -41.80907 -111.16013 -6.23597  1.000 39.54145  ? 198 TYR A O   1 
ATOM   1279 C  CB  . TYR A 1 199 ? -44.18089 -112.46881 -7.67574  1.000 36.22161  ? 198 TYR A CB  1 
ATOM   1280 C  CG  . TYR A 1 199 ? -44.98574 -113.24443 -8.69540  1.000 33.74487  ? 198 TYR A CG  1 
ATOM   1281 C  CD1 . TYR A 1 199 ? -44.55341 -114.48327 -9.14112  1.000 37.09751  ? 198 TYR A CD1 1 
ATOM   1282 C  CD2 . TYR A 1 199 ? -46.19994 -112.75673 -9.17988  1.000 36.45762  ? 198 TYR A CD2 1 
ATOM   1283 C  CE1 . TYR A 1 199 ? -45.29056 -115.21773 -10.05762 1.000 36.56442  ? 198 TYR A CE1 1 
ATOM   1284 C  CE2 . TYR A 1 199 ? -46.95320 -113.48699 -10.10094 1.000 34.84396  ? 198 TYR A CE2 1 
ATOM   1285 C  CZ  . TYR A 1 199 ? -46.48107 -114.71660 -10.53896 1.000 35.60238  ? 198 TYR A CZ  1 
ATOM   1286 O  OH  . TYR A 1 199 ? -47.20254 -115.46585 -11.44214 1.000 35.67078  ? 198 TYR A OH  1 
ATOM   1287 N  N   . THR A 1 200 ? -42.91018 -109.41633 -7.15432  1.000 43.23767  ? 199 THR A N   1 
ATOM   1288 C  CA  . THR A 1 200 ? -42.53497 -108.47969 -6.09911  1.000 43.70328  ? 199 THR A CA  1 
ATOM   1289 C  C   . THR A 1 200 ? -43.73657 -107.92506 -5.34296  1.000 49.02787  ? 199 THR A C   1 
ATOM   1290 O  O   . THR A 1 200 ? -43.56103 -107.04815 -4.48679  1.000 46.79222  ? 199 THR A O   1 
ATOM   1291 C  CB  . THR A 1 200 ? -41.70481 -107.32009 -6.67798  1.000 48.89080  ? 199 THR A CB  1 
ATOM   1292 O  OG1 . THR A 1 200 ? -42.39611 -106.74874 -7.79159  1.000 45.02009  ? 199 THR A OG1 1 
ATOM   1293 C  CG2 . THR A 1 200 ? -40.34948 -107.82046 -7.15523  1.000 46.71443  ? 199 THR A CG2 1 
ATOM   1294 N  N   . ASP A 1 201 ? -44.94512 -108.40698 -5.63479  1.000 44.50687  ? 200 ASP A N   1 
ATOM   1295 C  CA  . ASP A 1 201 ? -46.16659 -108.01654 -4.94605  1.000 48.84365  ? 200 ASP A CA  1 
ATOM   1296 C  C   . ASP A 1 201 ? -46.80283 -109.25113 -4.31830  1.000 37.25022  ? 200 ASP A C   1 
ATOM   1297 O  O   . ASP A 1 201 ? -46.66375 -110.36365 -4.83838  1.000 41.80280  ? 200 ASP A O   1 
ATOM   1298 C  CB  . ASP A 1 201 ? -47.17489 -107.36065 -5.91137  1.000 47.60834  ? 200 ASP A CB  1 
ATOM   1299 C  CG  . ASP A 1 201 ? -47.74179 -108.35314 -6.94087  1.000 55.85091  ? 200 ASP A CG  1 
ATOM   1300 O  OD1 . ASP A 1 201 ? -46.97299 -108.87017 -7.79667  1.000 56.53588  ? 200 ASP A OD1 1 
ATOM   1301 O  OD2 . ASP A 1 201 ? -48.96147 -108.63145 -6.88724  1.000 53.43508  ? 200 ASP A OD2 1 
ATOM   1302 N  N   . PHE A 1 202 ? -47.50321 -109.05719 -3.19794  1.000 38.82604  ? 201 PHE A N   1 
ATOM   1303 C  CA  . PHE A 1 202 ? -48.19403 -110.16922 -2.54378  1.000 40.36726  ? 201 PHE A CA  1 
ATOM   1304 C  C   . PHE A 1 202 ? -49.26387 -109.63227 -1.60458  1.000 41.89626  ? 201 PHE A C   1 
ATOM   1305 O  O   . PHE A 1 202 ? -48.98774 -108.74191 -0.79291  1.000 43.36396  ? 201 PHE A O   1 
ATOM   1306 C  CB  . PHE A 1 202 ? -47.21252 -111.05101 -1.76626  1.000 34.33524  ? 201 PHE A CB  1 
ATOM   1307 C  CG  . PHE A 1 202 ? -47.87145 -112.17105 -1.00090  1.000 38.63582  ? 201 PHE A CG  1 
ATOM   1308 C  CD1 . PHE A 1 202 ? -48.32409 -113.30510 -1.65832  1.000 37.21093  ? 201 PHE A CD1 1 
ATOM   1309 C  CD2 . PHE A 1 202 ? -48.03864 -112.08649 0.37435   1.000 38.24959  ? 201 PHE A CD2 1 
ATOM   1310 C  CE1 . PHE A 1 202 ? -48.92576 -114.34717 -0.94982  1.000 37.52096  ? 201 PHE A CE1 1 
ATOM   1311 C  CE2 . PHE A 1 202 ? -48.64454 -113.11662 1.08415   1.000 38.08465  ? 201 PHE A CE2 1 
ATOM   1312 C  CZ  . PHE A 1 202 ? -49.07486 -114.25020 0.42423   1.000 32.77981  ? 201 PHE A CZ  1 
ATOM   1313 N  N   . ASP A 1 203 ? -50.47509 -110.19162 -1.70900  1.000 37.94328  ? 202 ASP A N   1 
ATOM   1314 C  CA  . ASP A 1 203 ? -51.61126 -109.80130 -0.88112  1.000 38.31276  ? 202 ASP A CA  1 
ATOM   1315 C  C   . ASP A 1 203 ? -52.33825 -111.01696 -0.31178  1.000 43.44124  ? 202 ASP A C   1 
ATOM   1316 O  O   . ASP A 1 203 ? -53.49360 -110.89502 0.10892   1.000 39.56107  ? 202 ASP A O   1 
ATOM   1317 C  CB  . ASP A 1 203 ? -52.60183 -108.93772 -1.67397  1.000 42.85467  ? 202 ASP A CB  1 
ATOM   1318 C  CG  . ASP A 1 203 ? -52.09586 -107.52643 -1.90249  1.000 50.98056  ? 202 ASP A CG  1 
ATOM   1319 N  N   . GLY A 1 204 ? -51.70083 -112.19044 -0.31605  1.000 40.55846  ? 203 GLY A N   1 
ATOM   1320 C  CA  . GLY A 1 204 ? -52.27895 -113.38777 0.26807   1.000 34.61512  ? 203 GLY A CA  1 
ATOM   1321 C  C   . GLY A 1 204 ? -52.07168 -113.42504 1.77053   1.000 41.15866  ? 203 GLY A C   1 
ATOM   1322 O  O   . GLY A 1 204 ? -51.87436 -112.39748 2.42205   1.000 38.36186  ? 203 GLY A O   1 
ATOM   1323 N  N   . THR A 1 205 ? -52.10316 -114.63639 2.32759   1.000 35.85262  ? 204 THR A N   1 
ATOM   1324 C  CA  . THR A 1 205 ? -52.07458 -114.82115 3.77567   1.000 33.67589  ? 204 THR A CA  1 
ATOM   1325 C  C   . THR A 1 205 ? -50.63219 -114.97450 4.24807   1.000 34.23337  ? 204 THR A C   1 
ATOM   1326 O  O   . THR A 1 205 ? -49.92461 -115.89681 3.82306   1.000 34.31899  ? 204 THR A O   1 
ATOM   1327 C  CB  . THR A 1 205 ? -52.91537 -116.03481 4.18387   1.000 36.29511  ? 204 THR A CB  1 
ATOM   1328 O  OG1 . THR A 1 205 ? -54.28490 -115.79778 3.83209   1.000 37.73300  ? 204 THR A OG1 1 
ATOM   1329 C  CG2 . THR A 1 205 ? -52.83671 -116.25669 5.65953   1.000 34.76762  ? 204 THR A CG2 1 
ATOM   1330 N  N   . ARG A 1 206 ? -50.21186 -114.08918 5.15356   1.000 34.22164  ? 205 ARG A N   1 
ATOM   1331 C  CA  . ARG A 1 206 ? -48.79333 -113.98762 5.49011   1.000 35.54725  ? 205 ARG A CA  1 
ATOM   1332 C  C   . ARG A 1 206 ? -48.25955 -115.25736 6.14845   1.000 32.33795  ? 205 ARG A C   1 
ATOM   1333 O  O   . ARG A 1 206 ? -47.11849 -115.65533 5.89013   1.000 32.67164  ? 205 ARG A O   1 
ATOM   1334 C  CB  . ARG A 1 206 ? -48.54485 -112.77650 6.39135   1.000 35.18031  ? 205 ARG A CB  1 
ATOM   1335 C  CG  . ARG A 1 206 ? -47.06286 -112.47763 6.58568   1.000 40.41906  ? 205 ARG A CG  1 
ATOM   1336 C  CD  . ARG A 1 206 ? -46.86026 -111.18868 7.35355   1.000 41.80951  ? 205 ARG A CD  1 
ATOM   1337 N  NE  . ARG A 1 206 ? -45.45295 -110.85240 7.52675   1.000 43.26434  ? 205 ARG A NE  1 
ATOM   1338 C  CZ  . ARG A 1 206 ? -44.75716 -110.10326 6.68136   1.000 46.29118  ? 205 ARG A CZ  1 
ATOM   1339 N  NH1 . ARG A 1 206 ? -45.28263 -109.66835 5.54713   1.000 40.82850  ? 205 ARG A NH1 1 
ATOM   1340 N  NH2 . ARG A 1 206 ? -43.50458 -109.77754 6.98278   1.000 46.76157  ? 205 ARG A NH2 1 
ATOM   1341 N  N   . VAL A 1 207 ? -49.04981 -115.90348 7.01129   1.000 31.84919  ? 206 VAL A N   1 
ATOM   1342 C  CA  . VAL A 1 207 ? -48.55468 -117.10878 7.67566   1.000 31.77908  ? 206 VAL A CA  1 
ATOM   1343 C  C   . VAL A 1 207 ? -48.45489 -118.30134 6.73526   1.000 30.58909  ? 206 VAL A C   1 
ATOM   1344 O  O   . VAL A 1 207 ? -47.89254 -119.33272 7.12808   1.000 35.47332  ? 206 VAL A O   1 
ATOM   1345 C  CB  . VAL A 1 207 ? -49.40338 -117.51304 8.90548   1.000 34.10632  ? 206 VAL A CB  1 
ATOM   1346 C  CG1 . VAL A 1 207 ? -49.25298 -116.48185 10.04140  1.000 35.07385  ? 206 VAL A CG1 1 
ATOM   1347 C  CG2 . VAL A 1 207 ? -50.86987 -117.71522 8.54029   1.000 37.06457  ? 206 VAL A CG2 1 
ATOM   1348 N  N   . TYR A 1 208 ? -48.97836 -118.19836 5.50522   1.000 34.18562  ? 207 TYR A N   1 
ATOM   1349 C  CA  . TYR A 1 208 ? -48.72689 -119.20766 4.47681   1.000 29.51873  ? 207 TYR A CA  1 
ATOM   1350 C  C   . TYR A 1 208 ? -47.67867 -118.76222 3.47147   1.000 31.89292  ? 207 TYR A C   1 
ATOM   1351 O  O   . TYR A 1 208 ? -47.40210 -119.50067 2.52021   1.000 32.66792  ? 207 TYR A O   1 
ATOM   1352 C  CB  . TYR A 1 208 ? -50.01934 -119.56744 3.72628   1.000 30.21436  ? 207 TYR A CB  1 
ATOM   1353 C  CG  . TYR A 1 208 ? -50.97994 -120.48697 4.45991   1.000 29.35683  ? 207 TYR A CG  1 
ATOM   1354 C  CD1 . TYR A 1 208 ? -51.78450 -120.00728 5.48802   1.000 30.82140  ? 207 TYR A CD1 1 
ATOM   1355 C  CD2 . TYR A 1 208 ? -51.09645 -121.82257 4.10626   1.000 25.25056  ? 207 TYR A CD2 1 
ATOM   1356 C  CE1 . TYR A 1 208 ? -52.67776 -120.84308 6.16293   1.000 30.91634  ? 207 TYR A CE1 1 
ATOM   1357 C  CE2 . TYR A 1 208 ? -51.99599 -122.66708 4.76127   1.000 29.50186  ? 207 TYR A CE2 1 
ATOM   1358 C  CZ  . TYR A 1 208 ? -52.78550 -122.16459 5.78322   1.000 30.66668  ? 207 TYR A CZ  1 
ATOM   1359 O  OH  . TYR A 1 208 ? -53.67273 -122.98831 6.42762   1.000 28.81466  ? 207 TYR A OH  1 
ATOM   1360 N  N   . SER A 1 209 ? -47.09218 -117.56467 3.64966   1.000 30.76541  ? 208 SER A N   1 
ATOM   1361 C  CA  . SER A 1 209 ? -46.19036 -117.01805 2.64385   1.000 31.81488  ? 208 SER A CA  1 
ATOM   1362 C  C   . SER A 1 209 ? -44.76401 -117.48390 2.90930   1.000 32.72222  ? 208 SER A C   1 
ATOM   1363 O  O   . SER A 1 209 ? -44.42396 -117.85473 4.03350   1.000 35.47899  ? 208 SER A O   1 
ATOM   1364 C  CB  . SER A 1 209 ? -46.27217 -115.48405 2.63436   1.000 32.66335  ? 208 SER A CB  1 
ATOM   1365 O  OG  . SER A 1 209 ? -45.60935 -114.92324 3.75120   1.000 33.19621  ? 208 SER A OG  1 
ATOM   1366 N  N   . PRO A 1 210 ? -43.90962 -117.51456 1.88884   1.000 34.67912  ? 209 PRO A N   1 
ATOM   1367 C  CA  . PRO A 1 210 ? -42.62233 -118.19403 2.02853   1.000 34.72821  ? 209 PRO A CA  1 
ATOM   1368 C  C   . PRO A 1 210 ? -41.56270 -117.26832 2.60068   1.000 35.66873  ? 209 PRO A C   1 
ATOM   1369 O  O   . PRO A 1 210 ? -41.69745 -116.03463 2.53399   1.000 37.01429  ? 209 PRO A O   1 
ATOM   1370 C  CB  . PRO A 1 210 ? -42.29766 -118.60289 0.58268   1.000 33.96170  ? 209 PRO A CB  1 
ATOM   1371 C  CG  . PRO A 1 210 ? -42.85388 -117.47030 -0.23296  1.000 38.74885  ? 209 PRO A CG  1 
ATOM   1372 C  CD  . PRO A 1 210 ? -44.13820 -117.06274 0.50171   1.000 34.74234  ? 209 PRO A CD  1 
ATOM   1373 N  N   . PRO A 1 211 ? -40.47513 -117.82637 3.14789   1.000 35.74485  ? 210 PRO A N   1 
ATOM   1374 C  CA  . PRO A 1 211 ? -39.44171 -116.97545 3.76425   1.000 36.81415  ? 210 PRO A CA  1 
ATOM   1375 C  C   . PRO A 1 211 ? -38.82886 -115.96780 2.81240   1.000 42.23717  ? 210 PRO A C   1 
ATOM   1376 O  O   . PRO A 1 211 ? -38.44354 -114.87632 3.25327   1.000 44.00427  ? 210 PRO A O   1 
ATOM   1377 C  CB  . PRO A 1 211 ? -38.37883 -117.97935 4.23749   1.000 38.70646  ? 210 PRO A CB  1 
ATOM   1378 C  CG  . PRO A 1 211 ? -39.02156 -119.32607 4.15487   1.000 39.45279  ? 210 PRO A CG  1 
ATOM   1379 C  CD  . PRO A 1 211 ? -40.09616 -119.25016 3.13531   1.000 36.00297  ? 210 PRO A CD  1 
ATOM   1380 N  N   . GLU A 1 212 ? -38.68467 -116.30494 1.52731   1.000 40.24922  ? 211 GLU A N   1 
ATOM   1381 C  CA  . GLU A 1 212 ? -38.09800 -115.33043 0.61435   1.000 39.92049  ? 211 GLU A CA  1 
ATOM   1382 C  C   . GLU A 1 212 ? -39.02569 -114.13533 0.42227   1.000 44.53127  ? 211 GLU A C   1 
ATOM   1383 O  O   . GLU A 1 212 ? -38.55289 -113.04014 0.09916   1.000 43.42486  ? 211 GLU A O   1 
ATOM   1384 C  CB  . GLU A 1 212 ? -37.74045 -115.98258 -0.72999  1.000 39.01644  ? 211 GLU A CB  1 
ATOM   1385 C  CG  . GLU A 1 212 ? -38.92465 -116.52004 -1.55485  1.000 36.00067  ? 211 GLU A CG  1 
ATOM   1386 C  CD  . GLU A 1 212 ? -39.33133 -117.94587 -1.18494  1.000 38.83328  ? 211 GLU A CD  1 
ATOM   1387 O  OE1 . GLU A 1 212 ? -38.99496 -118.41389 -0.07613  1.000 34.47102  ? 211 GLU A OE1 1 
ATOM   1388 O  OE2 . GLU A 1 212 ? -39.98221 -118.60666 -2.02212  1.000 42.87741  ? 211 GLU A OE2 1 
ATOM   1389 N  N   . TRP A 1 213 ? -40.33994 -114.31485 0.62362   1.000 41.29100  ? 212 TRP A N   1 
ATOM   1390 C  CA  . TRP A 1 213 ? -41.23814 -113.16076 0.64195   1.000 42.93876  ? 212 TRP A CA  1 
ATOM   1391 C  C   . TRP A 1 213 ? -41.01099 -112.32243 1.89294   1.000 41.72147  ? 212 TRP A C   1 
ATOM   1392 O  O   . TRP A 1 213 ? -40.85087 -111.09802 1.81001   1.000 42.33330  ? 212 TRP A O   1 
ATOM   1393 C  CB  . TRP A 1 213 ? -42.71340 -113.58236 0.56074   1.000 35.00072  ? 212 TRP A CB  1 
ATOM   1394 C  CG  . TRP A 1 213 ? -43.62928 -112.42009 0.91467   1.000 40.29751  ? 212 TRP A CG  1 
ATOM   1395 C  CD1 . TRP A 1 213 ? -44.38766 -112.27826 2.04886   1.000 35.78212  ? 212 TRP A CD1 1 
ATOM   1396 C  CD2 . TRP A 1 213 ? -43.82679 -111.21415 0.15133   1.000 40.75625  ? 212 TRP A CD2 1 
ATOM   1397 N  NE1 . TRP A 1 213 ? -45.05945 -111.07015 2.02316   1.000 37.41606  ? 212 TRP A NE1 1 
ATOM   1398 C  CE2 . TRP A 1 213 ? -44.72165 -110.39560 0.87864   1.000 38.72712  ? 212 TRP A CE2 1 
ATOM   1399 C  CE3 . TRP A 1 213 ? -43.34410 -110.75553 -1.07795  1.000 36.67045  ? 212 TRP A CE3 1 
ATOM   1400 C  CZ2 . TRP A 1 213 ? -45.15055 -109.14664 0.40713   1.000 42.65243  ? 212 TRP A CZ2 1 
ATOM   1401 C  CZ3 . TRP A 1 213 ? -43.76408 -109.50105 -1.54100  1.000 42.34348  ? 212 TRP A CZ3 1 
ATOM   1402 C  CH2 . TRP A 1 213 ? -44.65048 -108.71313 -0.79541  1.000 41.25807  ? 212 TRP A CH2 1 
ATOM   1403 N  N   . ILE A 1 214 ? -40.99826 -112.96892 3.06287   1.000 41.22847  ? 213 ILE A N   1 
ATOM   1404 C  CA  . ILE A 1 214 ? -40.77997 -112.25577 4.32087   1.000 40.88761  ? 213 ILE A CA  1 
ATOM   1405 C  C   . ILE A 1 214 ? -39.47669 -111.46916 4.27033   1.000 46.59356  ? 213 ILE A C   1 
ATOM   1406 O  O   . ILE A 1 214 ? -39.41884 -110.30340 4.67901   1.000 48.99753  ? 213 ILE A O   1 
ATOM   1407 C  CB  . ILE A 1 214 ? -40.78313 -113.23374 5.51254   1.000 41.96771  ? 213 ILE A CB  1 
ATOM   1408 C  CG1 . ILE A 1 214 ? -42.09771 -114.02378 5.60876   1.000 38.42727  ? 213 ILE A CG1 1 
ATOM   1409 C  CG2 . ILE A 1 214 ? -40.44512 -112.48330 6.82019   1.000 42.84339  ? 213 ILE A CG2 1 
ATOM   1410 C  CD1 . ILE A 1 214 ? -43.35296 -113.19289 5.77190   1.000 42.31793  ? 213 ILE A CD1 1 
ATOM   1411 N  N   . ARG A 1 215 ? -38.41111 -112.09228 3.76206   1.000 41.10622  ? 214 ARG A N   1 
ATOM   1412 C  CA  . ARG A 1 215 ? -37.08350 -111.48958 3.86334   1.000 46.48408  ? 214 ARG A CA  1 
ATOM   1413 C  C   . ARG A 1 215 ? -36.80322 -110.49600 2.74177   1.000 47.37375  ? 214 ARG A C   1 
ATOM   1414 O  O   . ARG A 1 215 ? -36.23806 -109.42591 2.98878   1.000 46.32596  ? 214 ARG A O   1 
ATOM   1415 C  CB  . ARG A 1 215 ? -36.01064 -112.58027 3.86779   1.000 48.15531  ? 214 ARG A CB  1 
ATOM   1416 C  CG  . ARG A 1 215 ? -35.94023 -113.38064 5.15736   1.000 51.43270  ? 214 ARG A CG  1 
ATOM   1417 C  CD  . ARG A 1 215 ? -34.97171 -114.55753 5.03397   1.000 58.18759  ? 214 ARG A CD  1 
ATOM   1418 N  NE  . ARG A 1 215 ? -33.57778 -114.14946 5.14433   1.000 67.96886  ? 214 ARG A NE  1 
ATOM   1419 C  CZ  . ARG A 1 215 ? -32.81027 -114.38977 6.19932   1.000 77.36023  ? 214 ARG A CZ  1 
ATOM   1420 N  NH2 . ARG A 1 215 ? -33.31165 -115.07273 7.22572   1.000 69.47313  ? 214 ARG A NH2 1 
ATOM   1421 N  N   . TYR A 1 216 ? -37.15521 -110.83574 1.50230   1.000 43.73714  ? 215 TYR A N   1 
ATOM   1422 C  CA  . TYR A 1 216 ? -36.72457 -110.05357 0.35288   1.000 48.17527  ? 215 TYR A CA  1 
ATOM   1423 C  C   . TYR A 1 216 ? -37.86087 -109.44759 -0.44870  1.000 43.05339  ? 215 TYR A C   1 
ATOM   1424 O  O   . TYR A 1 216 ? -37.59051 -108.67477 -1.37481  1.000 47.45435  ? 215 TYR A O   1 
ATOM   1425 C  CB  . TYR A 1 216 ? -35.86454 -110.91664 -0.58261  1.000 44.87850  ? 215 TYR A CB  1 
ATOM   1426 C  CG  . TYR A 1 216 ? -34.79417 -111.68021 0.15723   1.000 50.96330  ? 215 TYR A CG  1 
ATOM   1427 C  CD1 . TYR A 1 216 ? -33.75329 -111.01173 0.79251   1.000 56.48429  ? 215 TYR A CD1 1 
ATOM   1428 C  CD2 . TYR A 1 216 ? -34.82392 -113.06946 0.22473   1.000 51.92062  ? 215 TYR A CD2 1 
ATOM   1429 C  CE1 . TYR A 1 216 ? -32.76983 -111.70219 1.47624   1.000 60.02254  ? 215 TYR A CE1 1 
ATOM   1430 C  CE2 . TYR A 1 216 ? -33.84297 -113.76884 0.90592   1.000 57.27860  ? 215 TYR A CE2 1 
ATOM   1431 C  CZ  . TYR A 1 216 ? -32.81843 -113.07995 1.52864   1.000 62.31679  ? 215 TYR A CZ  1 
ATOM   1432 O  OH  . TYR A 1 216 ? -31.84108 -113.77026 2.20897   1.000 70.99854  ? 215 TYR A OH  1 
ATOM   1433 N  N   . HIS A 1 217 ? -39.11048 -109.77883 -0.13426  1.000 44.43472  ? 216 HIS A N   1 
ATOM   1434 C  CA  . HIS A 1 217 ? -40.26636 -109.31819 -0.90097  1.000 44.48588  ? 216 HIS A CA  1 
ATOM   1435 C  C   . HIS A 1 217 ? -40.16073 -109.72061 -2.37041  1.000 44.92855  ? 216 HIS A C   1 
ATOM   1436 O  O   . HIS A 1 217 ? -40.55438 -108.97341 -3.27045  1.000 39.84450  ? 216 HIS A O   1 
ATOM   1437 C  CB  . HIS A 1 217 ? -40.45911 -107.80859 -0.74135  1.000 47.71018  ? 216 HIS A CB  1 
ATOM   1438 C  CG  . HIS A 1 217 ? -41.25453 -107.44316 0.47239   1.000 57.78341  ? 216 HIS A CG  1 
ATOM   1439 N  ND1 . HIS A 1 217 ? -41.88692 -106.22621 0.61595   1.000 65.95283  ? 216 HIS A ND1 1 
ATOM   1440 C  CD2 . HIS A 1 217 ? -41.52884 -108.14526 1.59914   1.000 55.81289  ? 216 HIS A CD2 1 
ATOM   1441 C  CE1 . HIS A 1 217 ? -42.51407 -106.19405 1.77970   1.000 66.83921  ? 216 HIS A CE1 1 
ATOM   1442 N  NE2 . HIS A 1 217 ? -42.31306 -107.34644 2.39558   1.000 64.14237  ? 216 HIS A NE2 1 
ATOM   1443 N  N   . ARG A 1 218 ? -39.62203 -110.92030 -2.60631  1.000 41.89152  ? 217 ARG A N   1 
ATOM   1444 C  CA  . ARG A 1 218 ? -39.43490 -111.49820 -3.93174  1.000 42.47934  ? 217 ARG A CA  1 
ATOM   1445 C  C   . ARG A 1 218 ? -39.68624 -112.99372 -3.84676  1.000 42.32723  ? 217 ARG A C   1 
ATOM   1446 O  O   . ARG A 1 218 ? -39.19645 -113.65505 -2.92717  1.000 38.16509  ? 217 ARG A O   1 
ATOM   1447 C  CB  . ARG A 1 218 ? -38.00928 -111.27075 -4.46957  1.000 46.19891  ? 217 ARG A CB  1 
ATOM   1448 C  CG  . ARG A 1 218 ? -37.70826 -109.86678 -4.95729  1.000 46.74451  ? 217 ARG A CG  1 
ATOM   1449 C  CD  . ARG A 1 218 ? -36.19890 -109.67254 -5.15475  1.000 53.24878  ? 217 ARG A CD  1 
ATOM   1450 N  NE  . ARG A 1 218 ? -35.66349 -110.45747 -6.26295  1.000 54.89832  ? 217 ARG A NE  1 
ATOM   1451 C  CZ  . ARG A 1 218 ? -35.55362 -110.00768 -7.50634  1.000 63.25630  ? 217 ARG A CZ  1 
ATOM   1452 N  NH1 . ARG A 1 218 ? -35.95224 -108.78835 -7.83638  1.000 63.61151  ? 217 ARG A NH1 1 
ATOM   1453 N  NH2 . ARG A 1 218 ? -35.02842 -110.79793 -8.44182  1.000 60.70051  ? 217 ARG A NH2 1 
ATOM   1454 N  N   . TYR A 1 219 ? -40.42846 -113.52865 -4.81089  1.000 38.80652  ? 218 TYR A N   1 
ATOM   1455 C  CA  . TYR A 1 219 ? -40.66726 -114.96595 -4.84525  1.000 36.03291  ? 218 TYR A CA  1 
ATOM   1456 C  C   . TYR A 1 219 ? -41.00322 -115.34743 -6.27497  1.000 41.43846  ? 218 TYR A C   1 
ATOM   1457 O  O   . TYR A 1 219 ? -41.41745 -114.50688 -7.07894  1.000 38.14269  ? 218 TYR A O   1 
ATOM   1458 C  CB  . TYR A 1 219 ? -41.79762 -115.39225 -3.88310  1.000 32.85234  ? 218 TYR A CB  1 
ATOM   1459 C  CG  . TYR A 1 219 ? -43.14299 -114.75888 -4.19939  1.000 36.73724  ? 218 TYR A CG  1 
ATOM   1460 C  CD1 . TYR A 1 219 ? -43.47588 -113.50360 -3.69800  1.000 36.89484  ? 218 TYR A CD1 1 
ATOM   1461 C  CD2 . TYR A 1 219 ? -44.06934 -115.40104 -5.02510  1.000 35.84401  ? 218 TYR A CD2 1 
ATOM   1462 C  CE1 . TYR A 1 219 ? -44.69967 -112.90595 -4.00035  1.000 35.84343  ? 218 TYR A CE1 1 
ATOM   1463 C  CE2 . TYR A 1 219 ? -45.30488 -114.81261 -5.32882  1.000 33.42678  ? 218 TYR A CE2 1 
ATOM   1464 C  CZ  . TYR A 1 219 ? -45.61258 -113.56488 -4.80929  1.000 38.73928  ? 218 TYR A CZ  1 
ATOM   1465 O  OH  . TYR A 1 219 ? -46.82067 -112.95576 -5.11308  1.000 34.58590  ? 218 TYR A OH  1 
ATOM   1466 N  N   . HIS A 1 220 ? -40.81291 -116.62624 -6.58320  1.000 35.86522  ? 219 HIS A N   1 
ATOM   1467 C  CA  . HIS A 1 220 ? -41.30658 -117.19070 -7.82631  1.000 31.47122  ? 219 HIS A CA  1 
ATOM   1468 C  C   . HIS A 1 220 ? -42.54191 -118.03947 -7.54476  1.000 33.28715  ? 219 HIS A C   1 
ATOM   1469 O  O   . HIS A 1 220 ? -42.69461 -118.60775 -6.45747  1.000 31.75385  ? 219 HIS A O   1 
ATOM   1470 C  CB  . HIS A 1 220 ? -40.21033 -117.99129 -8.52375  1.000 33.53819  ? 219 HIS A CB  1 
ATOM   1471 C  CG  . HIS A 1 220 ? -39.11642 -117.11902 -9.05946  1.000 35.47573  ? 219 HIS A CG  1 
ATOM   1472 N  ND1 . HIS A 1 220 ? -38.09407 -116.64213 -8.26693  1.000 40.86950  ? 219 HIS A ND1 1 
ATOM   1473 C  CD2 . HIS A 1 220 ? -38.93112 -116.57150 -10.28391 1.000 37.21498  ? 219 HIS A CD2 1 
ATOM   1474 C  CE1 . HIS A 1 220 ? -37.29987 -115.87076 -8.99289  1.000 39.15792  ? 219 HIS A CE1 1 
ATOM   1475 N  NE2 . HIS A 1 220 ? -37.78699 -115.81084 -10.22021 1.000 41.89464  ? 219 HIS A NE2 1 
ATOM   1476 N  N   . GLY A 1 221 ? -43.43471 -118.10020 -8.53623  1.000 36.08254  ? 220 GLY A N   1 
ATOM   1477 C  CA  . GLY A 1 221 ? -44.78946 -118.56891 -8.26579  1.000 34.26045  ? 220 GLY A CA  1 
ATOM   1478 C  C   . GLY A 1 221 ? -44.84660 -120.00714 -7.79232  1.000 32.22791  ? 220 GLY A C   1 
ATOM   1479 O  O   . GLY A 1 221 ? -45.49616 -120.31980 -6.78968  1.000 32.19382  ? 220 GLY A O   1 
ATOM   1480 N  N   . ARG A 1 222 ? -44.19648 -120.91007 -8.52450  1.000 31.56052  ? 221 ARG A N   1 
ATOM   1481 C  CA  . ARG A 1 222 ? -44.39025 -122.32732 -8.24709  1.000 34.72001  ? 221 ARG A CA  1 
ATOM   1482 C  C   . ARG A 1 222 ? -43.75971 -122.72480 -6.92276  1.000 31.42761  ? 221 ARG A C   1 
ATOM   1483 O  O   . ARG A 1 222 ? -44.36067 -123.47781 -6.14443  1.000 32.27511  ? 221 ARG A O   1 
ATOM   1484 C  CB  . ARG A 1 222 ? -43.82960 -123.17415 -9.39379  1.000 33.53538  ? 221 ARG A CB  1 
ATOM   1485 C  CG  . ARG A 1 222 ? -44.61500 -123.00758 -10.70550 1.000 42.55316  ? 221 ARG A CG  1 
ATOM   1486 C  CD  . ARG A 1 222 ? -44.02611 -123.84385 -11.83996 1.000 43.91550  ? 221 ARG A CD  1 
ATOM   1487 N  NE  . ARG A 1 222 ? -44.58821 -123.49655 -13.14690 1.000 53.19314  ? 221 ARG A NE  1 
ATOM   1488 C  CZ  . ARG A 1 222 ? -44.16525 -122.49351 -13.91064 1.000 51.53210  ? 221 ARG A CZ  1 
ATOM   1489 N  NH1 . ARG A 1 222 ? -43.21265 -121.66140 -13.50458 1.000 51.00140  ? 221 ARG A NH1 1 
ATOM   1490 N  NH2 . ARG A 1 222 ? -44.70354 -122.32292 -15.11759 1.000 54.25323  ? 221 ARG A NH2 1 
ATOM   1491 N  N   . SER A 1 223 ? -42.54593 -122.24469 -6.64565  1.000 30.60541  ? 222 SER A N   1 
ATOM   1492 C  CA  . SER A 1 223 ? -41.90803 -122.63632 -5.39594  1.000 29.65629  ? 222 SER A CA  1 
ATOM   1493 C  C   . SER A 1 223 ? -42.58801 -121.98035 -4.20377  1.000 32.77505  ? 222 SER A C   1 
ATOM   1494 O  O   . SER A 1 223 ? -42.62809 -122.56794 -3.11770  1.000 30.87354  ? 222 SER A O   1 
ATOM   1495 C  CB  . SER A 1 223 ? -40.41570 -122.29734 -5.42836  1.000 30.68967  ? 222 SER A CB  1 
ATOM   1496 O  OG  . SER A 1 223 ? -40.22334 -120.96815 -5.88071  1.000 37.43390  ? 222 SER A OG  1 
ATOM   1497 N  N   . ALA A 1 224 ? -43.14766 -120.78053 -4.38358  1.000 31.49813  ? 223 ALA A N   1 
ATOM   1498 C  CA  . ALA A 1 224 ? -43.93956 -120.19997 -3.30172  1.000 31.48190  ? 223 ALA A CA  1 
ATOM   1499 C  C   . ALA A 1 224 ? -45.20887 -121.01224 -3.05768  1.000 31.41014  ? 223 ALA A C   1 
ATOM   1500 O  O   . ALA A 1 224 ? -45.61085 -121.21526 -1.90384  1.000 29.14900  ? 223 ALA A O   1 
ATOM   1501 C  CB  . ALA A 1 224 ? -44.28296 -118.73419 -3.60735  1.000 30.46714  ? 223 ALA A CB  1 
ATOM   1502 N  N   . ALA A 1 225 ? -45.85941 -121.48217 -4.12791  1.000 30.94905  ? 224 ALA A N   1 
ATOM   1503 C  CA  . ALA A 1 225 ? -47.04661 -122.32161 -3.94297  1.000 28.96307  ? 224 ALA A CA  1 
ATOM   1504 C  C   . ALA A 1 225 ? -46.70154 -123.59060 -3.17680  1.000 31.30874  ? 224 ALA A C   1 
ATOM   1505 O  O   . ALA A 1 225 ? -47.44250 -124.00653 -2.27141  1.000 28.22885  ? 224 ALA A O   1 
ATOM   1506 C  CB  . ALA A 1 225 ? -47.67475 -122.66958 -5.29949  1.000 27.99008  ? 224 ALA A CB  1 
ATOM   1507 N  N   . VAL A 1 226 ? -45.56736 -124.20881 -3.51416  1.000 29.04314  ? 225 VAL A N   1 
ATOM   1508 C  CA  . VAL A 1 226 ? -45.14333 -125.42889 -2.82744  1.000 26.55564  ? 225 VAL A CA  1 
ATOM   1509 C  C   . VAL A 1 226 ? -44.93642 -125.16791 -1.33660  1.000 27.46250  ? 225 VAL A C   1 
ATOM   1510 O  O   . VAL A 1 226 ? -45.30144 -125.99286 -0.49069  1.000 28.51563  ? 225 VAL A O   1 
ATOM   1511 C  CB  . VAL A 1 226 ? -43.87880 -125.99530 -3.49947  1.000 25.68500  ? 225 VAL A CB  1 
ATOM   1512 C  CG1 . VAL A 1 226 ? -43.20382 -127.07423 -2.61041  1.000 28.00541  ? 225 VAL A CG1 1 
ATOM   1513 C  CG2 . VAL A 1 226 ? -44.25662 -126.59170 -4.87634  1.000 28.61572  ? 225 VAL A CG2 1 
ATOM   1514 N  N   . TRP A 1 227 ? -44.34207 -124.02885 -0.98718  1.000 28.28858  ? 226 TRP A N   1 
ATOM   1515 C  CA  . TRP A 1 227 ? -44.22739 -123.67927 0.42687   1.000 29.98940  ? 226 TRP A CA  1 
ATOM   1516 C  C   . TRP A 1 227 ? -45.60098 -123.64688 1.09567   1.000 27.41665  ? 226 TRP A C   1 
ATOM   1517 O  O   . TRP A 1 227 ? -45.80425 -124.26197 2.15214   1.000 26.24966  ? 226 TRP A O   1 
ATOM   1518 C  CB  . TRP A 1 227 ? -43.52146 -122.32859 0.59373   1.000 31.15001  ? 226 TRP A CB  1 
ATOM   1519 C  CG  . TRP A 1 227 ? -43.50606 -121.87202 2.03015   1.000 30.68401  ? 226 TRP A CG  1 
ATOM   1520 C  CD1 . TRP A 1 227 ? -44.52041 -121.23169 2.70008   1.000 29.98628  ? 226 TRP A CD1 1 
ATOM   1521 C  CD2 . TRP A 1 227 ? -42.43642 -122.02448 2.97895   1.000 27.91031  ? 226 TRP A CD2 1 
ATOM   1522 N  NE1 . TRP A 1 227 ? -44.14619 -120.97577 3.99564   1.000 28.37449  ? 226 TRP A NE1 1 
ATOM   1523 C  CE2 . TRP A 1 227 ? -42.87575 -121.45270 4.19775   1.000 29.71247  ? 226 TRP A CE2 1 
ATOM   1524 C  CE3 . TRP A 1 227 ? -41.15723 -122.58864 2.91979   1.000 31.93369  ? 226 TRP A CE3 1 
ATOM   1525 C  CZ2 . TRP A 1 227 ? -42.07953 -121.43199 5.34974   1.000 30.50537  ? 226 TRP A CZ2 1 
ATOM   1526 C  CZ3 . TRP A 1 227 ? -40.36140 -122.56134 4.07324   1.000 33.72090  ? 226 TRP A CZ3 1 
ATOM   1527 C  CH2 . TRP A 1 227 ? -40.82907 -121.99034 5.26614   1.000 31.98615  ? 226 TRP A CH2 1 
ATOM   1528 N  N   . SER A 1 228 ? -46.56281 -122.93729 0.49032   1.000 30.07555  ? 227 SER A N   1 
ATOM   1529 C  CA  . SER A 1 228 ? -47.90091 -122.85298 1.09302   1.000 31.58672  ? 227 SER A CA  1 
ATOM   1530 C  C   . SER A 1 228 ? -48.54945 -124.22878 1.21218   1.000 24.65523  ? 227 SER A C   1 
ATOM   1531 O  O   . SER A 1 228 ? -49.32817 -124.48214 2.13908   1.000 26.16356  ? 227 SER A O   1 
ATOM   1532 C  CB  . SER A 1 228 ? -48.80181 -121.89897 0.28263   1.000 30.08802  ? 227 SER A CB  1 
ATOM   1533 O  OG  . SER A 1 228 ? -49.24681 -122.45552 -0.95434  1.000 30.70832  ? 227 SER A OG  1 
ATOM   1534 N  N   . LEU A 1 229 ? -48.23758 -125.12593 0.28969   1.000 27.46666  ? 228 LEU A N   1 
ATOM   1535 C  CA  . LEU A 1 229 ? -48.76608 -126.47965 0.36286   1.000 25.82815  ? 228 LEU A CA  1 
ATOM   1536 C  C   . LEU A 1 229 ? -48.12676 -127.26545 1.49870   1.000 24.73811  ? 228 LEU A C   1 
ATOM   1537 O  O   . LEU A 1 229 ? -48.78773 -128.10582 2.11027   1.000 27.47344  ? 228 LEU A O   1 
ATOM   1538 C  CB  . LEU A 1 229 ? -48.54772 -127.17210 -0.98510  1.000 25.74120  ? 228 LEU A CB  1 
ATOM   1539 C  CG  . LEU A 1 229 ? -49.47754 -126.64254 -2.07958  1.000 27.48117  ? 228 LEU A CG  1 
ATOM   1540 C  CD1 . LEU A 1 229 ? -48.93983 -127.00641 -3.47208  1.000 29.18750  ? 228 LEU A CD1 1 
ATOM   1541 C  CD2 . LEU A 1 229 ? -50.89587 -127.24706 -1.87859  1.000 27.23819  ? 228 LEU A CD2 1 
ATOM   1542 N  N   . GLY A 1 230 ? -46.84693 -127.01307 1.79310   1.000 24.78262  ? 229 GLY A N   1 
ATOM   1543 C  CA  . GLY A 1 230 ? -46.25392 -127.59049 2.99025   1.000 26.42330  ? 229 GLY A CA  1 
ATOM   1544 C  C   . GLY A 1 230 ? -46.94852 -127.11571 4.25727   1.000 28.38354  ? 229 GLY A C   1 
ATOM   1545 O  O   . GLY A 1 230 ? -47.23212 -127.90938 5.15550   1.000 25.90411  ? 229 GLY A O   1 
ATOM   1546 N  N   . ILE A 1 231 ? -47.24550 -125.81440 4.33588   1.000 24.41596  ? 230 ILE A N   1 
ATOM   1547 C  CA  . ILE A 1 231 ? -47.98425 -125.27971 5.47892   1.000 26.31259  ? 230 ILE A CA  1 
ATOM   1548 C  C   . ILE A 1 231 ? -49.33635 -125.97407 5.59664   1.000 27.27076  ? 230 ILE A C   1 
ATOM   1549 O  O   . ILE A 1 231 ? -49.76204 -126.36132 6.69313   1.000 31.03001  ? 230 ILE A O   1 
ATOM   1550 C  CB  . ILE A 1 231 ? -48.15461 -123.74596 5.34589   1.000 30.31112  ? 230 ILE A CB  1 
ATOM   1551 C  CG1 . ILE A 1 231 ? -46.79379 -123.03624 5.23273   1.000 27.39260  ? 230 ILE A CG1 1 
ATOM   1552 C  CG2 . ILE A 1 231 ? -48.94063 -123.19883 6.54844   1.000 24.01965  ? 230 ILE A CG2 1 
ATOM   1553 C  CD1 . ILE A 1 231 ? -45.90351 -123.17204 6.53091   1.000 23.19940  ? 230 ILE A CD1 1 
ATOM   1554 N  N   . LEU A 1 232 ? -50.02509 -126.14094 4.46282   1.000 25.24707  ? 231 LEU A N   1 
ATOM   1555 C  CA  . LEU A 1 232 ? -51.35002 -126.76701 4.44920   1.000 24.30763  ? 231 LEU A CA  1 
ATOM   1556 C  C   . LEU A 1 232 ? -51.29124 -128.22114 4.89553   1.000 25.64190  ? 231 LEU A C   1 
ATOM   1557 O  O   . LEU A 1 232 ? -52.17552 -128.69692 5.61595   1.000 27.74951  ? 231 LEU A O   1 
ATOM   1558 C  CB  . LEU A 1 232 ? -51.94628 -126.68676 3.04165   1.000 23.20201  ? 231 LEU A CB  1 
ATOM   1559 C  CG  . LEU A 1 232 ? -53.30041 -127.38232 2.85218   1.000 26.91556  ? 231 LEU A CG  1 
ATOM   1560 C  CD1 . LEU A 1 232 ? -54.36089 -126.65366 3.64382   1.000 29.13001  ? 231 LEU A CD1 1 
ATOM   1561 C  CD2 . LEU A 1 232 ? -53.67767 -127.39724 1.38775   1.000 24.73581  ? 231 LEU A CD2 1 
ATOM   1562 N  N   . LEU A 1 233 ? -50.28137 -128.95702 4.44080   1.000 27.18576  ? 232 LEU A N   1 
ATOM   1563 C  CA  . LEU A 1 233 ? -50.17063 -130.36040 4.82581   1.000 25.21067  ? 232 LEU A CA  1 
ATOM   1564 C  C   . LEU A 1 233 ? -49.88669 -130.50984 6.31681   1.000 26.51159  ? 232 LEU A C   1 
ATOM   1565 O  O   . LEU A 1 233 ? -50.47566 -131.36469 6.99007   1.000 29.29357  ? 232 LEU A O   1 
ATOM   1566 C  CB  . LEU A 1 233 ? -49.07913 -131.03223 3.98958   1.000 22.98322  ? 232 LEU A CB  1 
ATOM   1567 C  CG  . LEU A 1 233 ? -48.86086 -132.51586 4.29339   1.000 27.50961  ? 232 LEU A CG  1 
ATOM   1568 C  CD1 . LEU A 1 233 ? -50.17828 -133.29353 4.17133   1.000 27.66550  ? 232 LEU A CD1 1 
ATOM   1569 C  CD2 . LEU A 1 233 ? -47.81311 -133.08354 3.32275   1.000 25.04383  ? 232 LEU A CD2 1 
ATOM   1570 N  N   . TYR A 1 234 ? -48.97085 -129.70824 6.84807   1.000 28.37657  ? 233 TYR A N   1 
ATOM   1571 C  CA  . TYR A 1 234 ? -48.76554 -129.69294 8.29264   1.000 26.30312  ? 233 TYR A CA  1 
ATOM   1572 C  C   . TYR A 1 234 ? -50.08503 -129.39487 9.01478   1.000 31.40996  ? 233 TYR A C   1 
ATOM   1573 O  O   . TYR A 1 234 ? -50.45795 -130.07398 9.97696   1.000 28.90269  ? 233 TYR A O   1 
ATOM   1574 C  CB  . TYR A 1 234 ? -47.67982 -128.65867 8.63433   1.000 27.70951  ? 233 TYR A CB  1 
ATOM   1575 C  CG  . TYR A 1 234 ? -47.32951 -128.64479 10.10486  1.000 29.97715  ? 233 TYR A CG  1 
ATOM   1576 C  CD1 . TYR A 1 234 ? -48.17381 -128.02879 11.02066  1.000 28.38991  ? 233 TYR A CD1 1 
ATOM   1577 C  CD2 . TYR A 1 234 ? -46.17544 -129.27646 10.58163  1.000 28.42703  ? 233 TYR A CD2 1 
ATOM   1578 C  CE1 . TYR A 1 234 ? -47.89323 -128.02955 12.39640  1.000 30.80710  ? 233 TYR A CE1 1 
ATOM   1579 C  CE2 . TYR A 1 234 ? -45.87259 -129.27711 11.95541  1.000 29.98919  ? 233 TYR A CE2 1 
ATOM   1580 C  CZ  . TYR A 1 234 ? -46.75723 -128.65678 12.85348  1.000 35.29277  ? 233 TYR A CZ  1 
ATOM   1581 O  OH  . TYR A 1 234 ? -46.49923 -128.63881 14.20428  1.000 32.24423  ? 233 TYR A OH  1 
ATOM   1582 N  N   . ASP A 1 235 ? -50.79150 -128.36020 8.56167   1.000 27.64364  ? 234 ASP A N   1 
ATOM   1583 C  CA  . ASP A 1 235 ? -52.11190 -128.01810 9.09425   1.000 29.48597  ? 234 ASP A CA  1 
ATOM   1584 C  C   . ASP A 1 235 ? -53.02983 -129.23979 9.16507   1.000 28.09695  ? 234 ASP A C   1 
ATOM   1585 O  O   . ASP A 1 235 ? -53.69472 -129.47549 10.17621  1.000 30.06111  ? 234 ASP A O   1 
ATOM   1586 C  CB  . ASP A 1 235 ? -52.70934 -126.92453 8.19461   1.000 27.00890  ? 234 ASP A CB  1 
ATOM   1587 C  CG  . ASP A 1 235 ? -54.04907 -126.40736 8.67914   1.000 33.33723  ? 234 ASP A CG  1 
ATOM   1588 O  OD1 . ASP A 1 235 ? -54.21746 -126.13847 9.88856   1.000 32.55586  ? 234 ASP A OD1 1 
ATOM   1589 O  OD2 . ASP A 1 235 ? -54.93446 -126.24519 7.81775   1.000 32.11767  ? 234 ASP A OD2 1 
ATOM   1590 N  N   . MET A 1 236 ? -53.07799 -130.03407 8.08944   1.000 29.80695  ? 235 MET A N   1 
ATOM   1591 C  CA  . MET A 1 236 ? -53.98346 -131.18150 8.04956   1.000 30.67947  ? 235 MET A CA  1 
ATOM   1592 C  C   . MET A 1 236 ? -53.58579 -132.25937 9.05786   1.000 32.62546  ? 235 MET A C   1 
ATOM   1593 O  O   . MET A 1 236 ? -54.43302 -132.77197 9.80323   1.000 31.84438  ? 235 MET A O   1 
ATOM   1594 C  CB  . MET A 1 236 ? -54.01721 -131.76228 6.62736   1.000 26.31861  ? 235 MET A CB  1 
ATOM   1595 C  CG  . MET A 1 236 ? -54.85995 -130.92007 5.65848   1.000 27.53554  ? 235 MET A CG  1 
ATOM   1596 S  SD  . MET A 1 236 ? -55.06888 -131.81354 4.09168   1.000 37.73031  ? 235 MET A SD  1 
ATOM   1597 C  CE  . MET A 1 236 ? -53.44316 -131.97156 3.59936   1.000 27.17874  ? 235 MET A CE  1 
ATOM   1598 N  N   . VAL A 1 237 ? -52.30051 -132.62637 9.09932   1.000 29.11886  ? 236 VAL A N   1 
ATOM   1599 C  CA  . VAL A 1 237 ? -51.90150 -133.75618 9.94444   1.000 30.40492  ? 236 VAL A CA  1 
ATOM   1600 C  C   . VAL A 1 237 ? -51.61353 -133.33928 11.37703  1.000 32.41274  ? 236 VAL A C   1 
ATOM   1601 O  O   . VAL A 1 237 ? -51.56495 -134.20741 12.26278  1.000 32.95605  ? 236 VAL A O   1 
ATOM   1602 C  CB  . VAL A 1 237 ? -50.69036 -134.51160 9.34479   1.000 30.25591  ? 236 VAL A CB  1 
ATOM   1603 C  CG1 . VAL A 1 237 ? -51.06039 -135.07427 7.96761   1.000 31.21738  ? 236 VAL A CG1 1 
ATOM   1604 C  CG2 . VAL A 1 237 ? -49.46422 -133.59916 9.23042   1.000 29.50884  ? 236 VAL A CG2 1 
ATOM   1605 N  N   . CYS A 1 238 ? -51.46106 -132.03908 11.65162  1.000 30.83238  ? 237 CYS A N   1 
ATOM   1606 C  CA  . CYS A 1 238 ? -51.19451 -131.60019 13.01267  1.000 31.31251  ? 237 CYS A CA  1 
ATOM   1607 C  C   . CYS A 1 238 ? -52.34866 -130.84648 13.65439  1.000 37.63832  ? 237 CYS A C   1 
ATOM   1608 O  O   . CYS A 1 238 ? -52.32838 -130.65542 14.87541  1.000 32.30430  ? 237 CYS A O   1 
ATOM   1609 C  CB  . CYS A 1 238 ? -49.92989 -130.73608 13.05859  1.000 31.16605  ? 237 CYS A CB  1 
ATOM   1610 S  SG  . CYS A 1 238 ? -48.42797 -131.74324 12.95504  1.000 36.84304  ? 237 CYS A SG  1 
ATOM   1611 N  N   . GLY A 1 239 ? -53.34687 -130.41624 12.88071  1.000 32.90666  ? 238 GLY A N   1 
ATOM   1612 C  CA  . GLY A 1 239 ? -54.48470 -129.72085 13.44046  1.000 34.08394  ? 238 GLY A CA  1 
ATOM   1613 C  C   . GLY A 1 239 ? -54.37338 -128.21200 13.44318  1.000 33.80148  ? 238 GLY A C   1 
ATOM   1614 O  O   . GLY A 1 239 ? -55.38385 -127.53520 13.67761  1.000 34.41205  ? 238 GLY A O   1 
ATOM   1615 N  N   . ASP A 1 240 ? -53.19117 -127.66297 13.17567  1.000 32.41933  ? 239 ASP A N   1 
ATOM   1616 C  CA  . ASP A 1 240 ? -53.02949 -126.22614 12.99229  1.000 31.02219  ? 239 ASP A CA  1 
ATOM   1617 C  C   . ASP A 1 240 ? -51.71775 -125.98793 12.25850  1.000 35.21351  ? 239 ASP A C   1 
ATOM   1618 O  O   . ASP A 1 240 ? -50.86942 -126.88104 12.14795  1.000 31.14894  ? 239 ASP A O   1 
ATOM   1619 C  CB  . ASP A 1 240 ? -53.06727 -125.46589 14.32859  1.000 32.80538  ? 239 ASP A CB  1 
ATOM   1620 C  CG  . ASP A 1 240 ? -53.43556 -123.99506 14.15529  1.000 40.66363  ? 239 ASP A CG  1 
ATOM   1621 O  OD1 . ASP A 1 240 ? -53.77908 -123.57616 13.02097  1.000 36.70643  ? 239 ASP A OD1 1 
ATOM   1622 O  OD2 . ASP A 1 240 ? -53.38294 -123.25178 15.15861  1.000 42.63364  ? 239 ASP A OD2 1 
ATOM   1623 N  N   . ILE A 1 241 ? -51.57114 -124.77152 11.74290  1.000 32.08546  ? 240 ILE A N   1 
ATOM   1624 C  CA  . ILE A 1 241 ? -50.41505 -124.40187 10.92890  1.000 29.84353  ? 240 ILE A CA  1 
ATOM   1625 C  C   . ILE A 1 241 ? -49.18394 -124.34886 11.82495  1.000 31.98411  ? 240 ILE A C   1 
ATOM   1626 O  O   . ILE A 1 241 ? -49.31503 -124.13028 13.03578  1.000 32.20720  ? 240 ILE A O   1 
ATOM   1627 C  CB  . ILE A 1 241 ? -50.63450 -123.05504 10.22589  1.000 32.90597  ? 240 ILE A CB  1 
ATOM   1628 C  CG1 . ILE A 1 241 ? -50.87518 -121.95089 11.27542  1.000 33.56841  ? 240 ILE A CG1 1 
ATOM   1629 C  CG2 . ILE A 1 241 ? -51.78289 -123.14403 9.22390   1.000 29.23625  ? 240 ILE A CG2 1 
ATOM   1630 C  CD1 . ILE A 1 241 ? -51.15991 -120.61855 10.64399  1.000 35.68122  ? 240 ILE A CD1 1 
ATOM   1631 N  N   . PRO A 1 242 ? -47.97984 -124.53862 11.28275  1.000 30.17129  ? 241 PRO A N   1 
ATOM   1632 C  CA  . PRO A 1 242 ? -46.78437 -124.59219 12.13263  1.000 32.76524  ? 241 PRO A CA  1 
ATOM   1633 C  C   . PRO A 1 242 ? -46.28620 -123.23466 12.61138  1.000 36.98782  ? 241 PRO A C   1 
ATOM   1634 O  O   . PRO A 1 242 ? -45.73729 -123.13336 13.71081  1.000 37.38303  ? 241 PRO A O   1 
ATOM   1635 C  CB  . PRO A 1 242 ? -45.75510 -125.27233 11.21860  1.000 30.75950  ? 241 PRO A CB  1 
ATOM   1636 C  CG  . PRO A 1 242 ? -46.16746 -124.83387 9.83857   1.000 30.55092  ? 241 PRO A CG  1 
ATOM   1637 C  CD  . PRO A 1 242 ? -47.66627 -124.80495 9.85979   1.000 31.97026  ? 241 PRO A CD  1 
ATOM   1638 N  N   . PHE A 1 243 ? -46.45706 -122.18469 11.81070  1.000 35.76425  ? 242 PHE A N   1 
ATOM   1639 C  CA  . PHE A 1 243 ? -45.82915 -120.90008 12.08453  1.000 37.01256  ? 242 PHE A CA  1 
ATOM   1640 C  C   . PHE A 1 243 ? -46.88472 -119.82176 12.26602  1.000 38.03948  ? 242 PHE A C   1 
ATOM   1641 O  O   . PHE A 1 243 ? -47.82154 -119.71840 11.46657  1.000 35.53234  ? 242 PHE A O   1 
ATOM   1642 C  CB  . PHE A 1 243 ? -44.89250 -120.47667 10.93988  1.000 35.18786  ? 242 PHE A CB  1 
ATOM   1643 C  CG  . PHE A 1 243 ? -43.91778 -121.53678 10.50915  1.000 35.50323  ? 242 PHE A CG  1 
ATOM   1644 C  CD1 . PHE A 1 243 ? -43.18124 -122.25635 11.44106  1.000 36.14352  ? 242 PHE A CD1 1 
ATOM   1645 C  CD2 . PHE A 1 243 ? -43.73906 -121.80640 9.15886   1.000 32.98753  ? 242 PHE A CD2 1 
ATOM   1646 C  CE1 . PHE A 1 243 ? -42.27460 -123.22485 11.03486  1.000 36.34968  ? 242 PHE A CE1 1 
ATOM   1647 C  CE2 . PHE A 1 243 ? -42.83212 -122.77477 8.73522   1.000 35.42801  ? 242 PHE A CE2 1 
ATOM   1648 C  CZ  . PHE A 1 243 ? -42.09618 -123.48335 9.66849   1.000 35.48841  ? 242 PHE A CZ  1 
ATOM   1649 N  N   . GLU A 1 244 ? -46.71181 -118.99517 13.30195  1.000 38.19739  ? 243 GLU A N   1 
ATOM   1650 C  CA  . GLU A 1 244 ? -47.52317 -117.79497 13.46082  1.000 38.47747  ? 243 GLU A CA  1 
ATOM   1651 C  C   . GLU A 1 244 ? -46.74541 -116.49180 13.30571  1.000 42.74691  ? 243 GLU A C   1 
ATOM   1652 O  O   . GLU A 1 244 ? -47.36766 -115.45433 13.06519  1.000 51.51939  ? 243 GLU A O   1 
ATOM   1653 C  CB  . GLU A 1 244 ? -48.22090 -117.78881 14.83378  1.000 44.08378  ? 243 GLU A CB  1 
ATOM   1654 C  CG  . GLU A 1 244 ? -49.23802 -118.91774 15.02737  1.000 45.48471  ? 243 GLU A CG  1 
ATOM   1655 C  CD  . GLU A 1 244 ? -50.53755 -118.70963 14.25934  1.000 44.81699  ? 243 GLU A CD  1 
ATOM   1656 O  OE1 . GLU A 1 244 ? -50.85923 -117.55422 13.89919  1.000 44.45105  ? 243 GLU A OE1 1 
ATOM   1657 O  OE2 . GLU A 1 244 ? -51.24925 -119.71641 14.01570  1.000 47.44545  ? 243 GLU A OE2 1 
ATOM   1658 N  N   . HIS A 1 245 ? -45.41865 -116.51072 13.42112  1.000 43.91959  ? 244 HIS A N   1 
ATOM   1659 C  CA  . HIS A 1 245 ? -44.61402 -115.29341 13.45845  1.000 44.47639  ? 244 HIS A CA  1 
ATOM   1660 C  C   . HIS A 1 245 ? -43.55114 -115.30410 12.36674  1.000 43.33414  ? 244 HIS A C   1 
ATOM   1661 O  O   . HIS A 1 245 ? -43.05632 -116.36493 11.97786  1.000 41.80625  ? 244 HIS A O   1 
ATOM   1662 C  CB  . HIS A 1 245 ? -43.92892 -115.13916 14.82403  1.000 47.86319  ? 244 HIS A CB  1 
ATOM   1663 C  CG  . HIS A 1 245 ? -44.87189 -115.23858 15.97952  1.000 53.06742  ? 244 HIS A CG  1 
ATOM   1664 N  ND1 . HIS A 1 245 ? -45.73857 -114.22193 16.32232  1.000 57.87380  ? 244 HIS A ND1 1 
ATOM   1665 C  CD2 . HIS A 1 245 ? -45.09116 -116.23641 16.86771  1.000 57.98623  ? 244 HIS A CD2 1 
ATOM   1666 C  CE1 . HIS A 1 245 ? -46.45292 -114.59140 17.37032  1.000 57.69972  ? 244 HIS A CE1 1 
ATOM   1667 N  NE2 . HIS A 1 245 ? -46.07735 -115.80818 17.72248  1.000 60.63117  ? 244 HIS A NE2 1 
ATOM   1668 N  N   . ASP A 1 246 ? -43.16840 -114.10490 11.90747  1.000 41.90038  ? 245 ASP A N   1 
ATOM   1669 C  CA  . ASP A 1 246 ? -42.13761 -113.99530 10.87129  1.000 46.33788  ? 245 ASP A CA  1 
ATOM   1670 C  C   . ASP A 1 246 ? -40.87119 -114.76014 11.23794  1.000 47.03085  ? 245 ASP A C   1 
ATOM   1671 O  O   . ASP A 1 246 ? -40.25552 -115.40675 10.37955  1.000 43.79460  ? 245 ASP A O   1 
ATOM   1672 C  CB  . ASP A 1 246 ? -41.78931 -112.53054 10.61226  1.000 42.62057  ? 245 ASP A CB  1 
ATOM   1673 C  CG  . ASP A 1 246 ? -42.86391 -111.80904 9.86421   1.000 44.04611  ? 245 ASP A CG  1 
ATOM   1674 O  OD1 . ASP A 1 246 ? -43.87060 -112.46002 9.52898   1.000 42.40300  ? 245 ASP A OD1 1 
ATOM   1675 O  OD2 . ASP A 1 246 ? -42.70867 -110.59226 9.61488   1.000 46.59766  ? 245 ASP A OD2 1 
ATOM   1676 N  N   . GLU A 1 247 ? -40.45864 -114.68567 12.50647  1.000 43.30590  ? 246 GLU A N   1 
ATOM   1677 C  CA  . GLU A 1 247 ? -39.23833 -115.36551 12.93231  1.000 45.06200  ? 246 GLU A CA  1 
ATOM   1678 C  C   . GLU A 1 247 ? -39.35349 -116.87706 12.76318  1.000 40.39101  ? 246 GLU A C   1 
ATOM   1679 O  O   . GLU A 1 247 ? -38.35814 -117.55011 12.47564  1.000 42.23595  ? 246 GLU A O   1 
ATOM   1680 C  CB  . GLU A 1 247 ? -38.91741 -115.01835 14.39082  1.000 48.50485  ? 246 GLU A CB  1 
ATOM   1681 C  CG  . GLU A 1 247 ? -39.18635 -113.56047 14.75905  1.000 60.29901  ? 246 GLU A CG  1 
ATOM   1682 C  CD  . GLU A 1 247 ? -40.64233 -113.30712 15.13195  1.000 60.77039  ? 246 GLU A CD  1 
ATOM   1683 O  OE2 . GLU A 1 247 ? -41.34110 -112.59802 14.37634  1.000 52.54464  ? 246 GLU A OE2 1 
ATOM   1684 N  N   . GLU A 1 248 ? -40.55336 -117.43209 12.97023  1.000 40.33904  ? 247 GLU A N   1 
ATOM   1685 C  CA  . GLU A 1 248 ? -40.75804 -118.86679 12.76382  1.000 44.03358  ? 247 GLU A CA  1 
ATOM   1686 C  C   . GLU A 1 248 ? -40.74899 -119.23051 11.28286  1.000 42.63740  ? 247 GLU A C   1 
ATOM   1687 O  O   . GLU A 1 248 ? -40.23986 -120.29511 10.90117  1.000 40.17079  ? 247 GLU A O   1 
ATOM   1688 C  CB  . GLU A 1 248 ? -42.07486 -119.30903 13.40335  1.000 43.33016  ? 247 GLU A CB  1 
ATOM   1689 C  CG  . GLU A 1 248 ? -42.10300 -119.15322 14.91707  1.000 42.74909  ? 247 GLU A CG  1 
ATOM   1690 C  CD  . GLU A 1 248 ? -43.47584 -119.41299 15.51782  1.000 50.42983  ? 247 GLU A CD  1 
ATOM   1691 O  OE1 . GLU A 1 248 ? -44.49553 -119.14179 14.85526  1.000 44.06836  ? 247 GLU A OE1 1 
ATOM   1692 O  OE2 . GLU A 1 248 ? -43.53912 -119.88319 16.66925  1.000 61.90137  ? 247 GLU A OE2 1 
ATOM   1693 N  N   . ILE A 1 249 ? -41.34084 -118.38060 10.43628  1.000 39.45026  ? 248 ILE A N   1 
ATOM   1694 C  CA  . ILE A 1 249 ? -41.34172 -118.64176 8.99680   1.000 40.42659  ? 248 ILE A CA  1 
ATOM   1695 C  C   . ILE A 1 249 ? -39.91167 -118.71516 8.47094   1.000 40.48834  ? 248 ILE A C   1 
ATOM   1696 O  O   . ILE A 1 249 ? -39.54557 -119.64003 7.74002   1.000 36.38165  ? 248 ILE A O   1 
ATOM   1697 C  CB  . ILE A 1 249 ? -42.16414 -117.56881 8.25467   1.000 38.20424  ? 248 ILE A CB  1 
ATOM   1698 C  CG1 . ILE A 1 249 ? -43.61592 -117.57222 8.74851   1.000 36.26666  ? 248 ILE A CG1 1 
ATOM   1699 C  CG2 . ILE A 1 249 ? -42.10043 -117.78161 6.74094   1.000 36.71021  ? 248 ILE A CG2 1 
ATOM   1700 C  CD1 . ILE A 1 249 ? -44.44344 -116.41553 8.20866   1.000 39.19142  ? 248 ILE A CD1 1 
ATOM   1701 N  N   . ILE A 1 250 ? -39.07059 -117.75070 8.85052   1.000 36.99136  ? 249 ILE A N   1 
ATOM   1702 C  CA  . ILE A 1 250 ? -37.71464 -117.72517 8.30912   1.000 43.43290  ? 249 ILE A CA  1 
ATOM   1703 C  C   . ILE A 1 250 ? -36.73927 -118.56832 9.11206   1.000 44.99174  ? 249 ILE A C   1 
ATOM   1704 O  O   . ILE A 1 250 ? -35.59823 -118.75726 8.66265   1.000 43.54726  ? 249 ILE A O   1 
ATOM   1705 C  CB  . ILE A 1 250 ? -37.17204 -116.28669 8.20705   1.000 51.07840  ? 249 ILE A CB  1 
ATOM   1706 C  CG1 . ILE A 1 250 ? -36.92185 -115.71567 9.60460   1.000 46.82880  ? 249 ILE A CG1 1 
ATOM   1707 C  CG2 . ILE A 1 250 ? -38.13985 -115.41877 7.41089   1.000 48.48564  ? 249 ILE A CG2 1 
ATOM   1708 C  CD1 . ILE A 1 250 ? -36.32685 -114.32708 9.59681   1.000 56.81522  ? 249 ILE A CD1 1 
ATOM   1709 N  N   . GLY A 1 251 ? -37.15490 -119.10829 10.26513  1.000 43.81041  ? 250 GLY A N   1 
ATOM   1710 C  CA  . GLY A 1 251 ? -36.23074 -119.85212 11.11160  1.000 41.50202  ? 250 GLY A CA  1 
ATOM   1711 C  C   . GLY A 1 251 ? -35.87974 -121.24227 10.62065  1.000 45.58261  ? 250 GLY A C   1 
ATOM   1712 O  O   . GLY A 1 251 ? -34.80526 -121.76017 10.94036  1.000 49.29710  ? 250 GLY A O   1 
ATOM   1713 N  N   . GLY A 1 252 ? -36.77153 -121.88314 9.87904   1.000 40.60765  ? 251 GLY A N   1 
ATOM   1714 C  CA  . GLY A 1 252 ? -36.42466 -123.15772 9.27908   1.000 52.26476  ? 251 GLY A CA  1 
ATOM   1715 C  C   . GLY A 1 252 ? -36.54206 -124.38428 10.16227  1.000 55.88198  ? 251 GLY A C   1 
ATOM   1716 O  O   . GLY A 1 252 ? -36.02368 -125.44218 9.78464   1.000 49.38280  ? 251 GLY A O   1 
ATOM   1717 N  N   . GLN A 1 253 ? -37.20379 -124.29435 11.31471  1.000 47.38506  ? 252 GLN A N   1 
ATOM   1718 C  CA  . GLN A 1 253 ? -37.37795 -125.43995 12.20023  1.000 46.45489  ? 252 GLN A CA  1 
ATOM   1719 C  C   . GLN A 1 253 ? -38.84833 -125.82641 12.23733  1.000 43.50071  ? 252 GLN A C   1 
ATOM   1720 O  O   . GLN A 1 253 ? -39.71470 -124.97406 12.45179  1.000 44.46097  ? 252 GLN A O   1 
ATOM   1721 C  CB  . GLN A 1 253 ? -36.87545 -125.13407 13.61206  1.000 46.03629  ? 252 GLN A CB  1 
ATOM   1722 C  CG  . GLN A 1 253 ? -35.37272 -124.86140 13.70439  1.000 52.85181  ? 252 GLN A CG  1 
ATOM   1723 C  CD  . GLN A 1 253 ? -34.93037 -124.56518 15.12102  1.000 60.21400  ? 252 GLN A CD  1 
ATOM   1724 N  N   . VAL A 1 254 ? -39.12911 -127.10645 12.03426  1.000 37.73673  ? 253 VAL A N   1 
ATOM   1725 C  CA  . VAL A 1 254 ? -40.49643 -127.60704 12.00765  1.000 33.09387  ? 253 VAL A CA  1 
ATOM   1726 C  C   . VAL A 1 254 ? -40.65544 -128.58263 13.16641  1.000 32.71474  ? 253 VAL A C   1 
ATOM   1727 O  O   . VAL A 1 254 ? -40.12335 -129.69850 13.12637  1.000 38.58723  ? 253 VAL A O   1 
ATOM   1728 C  CB  . VAL A 1 254 ? -40.83909 -128.27092 10.66707  1.000 39.29588  ? 253 VAL A CB  1 
ATOM   1729 C  CG1 . VAL A 1 254 ? -42.27471 -128.80410 10.68940  1.000 38.97725  ? 253 VAL A CG1 1 
ATOM   1730 C  CG2 . VAL A 1 254 ? -40.64919 -127.26633 9.52954   1.000 36.35226  ? 253 VAL A CG2 1 
ATOM   1731 N  N   . PHE A 1 255 ? -41.38182 -128.16117 14.19597  1.000 33.94312  ? 254 PHE A N   1 
ATOM   1732 C  CA  . PHE A 1 255 ? -41.71257 -129.01397 15.33300  1.000 37.73781  ? 254 PHE A CA  1 
ATOM   1733 C  C   . PHE A 1 255 ? -43.06041 -129.67762 15.07341  1.000 35.93155  ? 254 PHE A C   1 
ATOM   1734 O  O   . PHE A 1 255 ? -44.03169 -128.99624 14.72389  1.000 31.37337  ? 254 PHE A O   1 
ATOM   1735 C  CB  . PHE A 1 255 ? -41.76624 -128.19842 16.63030  1.000 34.47911  ? 254 PHE A CB  1 
ATOM   1736 C  CG  . PHE A 1 255 ? -42.30707 -128.97652 17.81760  1.000 37.11472  ? 254 PHE A CG  1 
ATOM   1737 C  CD1 . PHE A 1 255 ? -41.47777 -129.80982 18.54653  1.000 41.39391  ? 254 PHE A CD1 1 
ATOM   1738 C  CD2 . PHE A 1 255 ? -43.64696 -128.89037 18.17826  1.000 39.26171  ? 254 PHE A CD2 1 
ATOM   1739 C  CE1 . PHE A 1 255 ? -41.96880 -130.53146 19.63650  1.000 39.98263  ? 254 PHE A CE1 1 
ATOM   1740 C  CE2 . PHE A 1 255 ? -44.14983 -129.61448 19.24067  1.000 37.35396  ? 254 PHE A CE2 1 
ATOM   1741 C  CZ  . PHE A 1 255 ? -43.30202 -130.43252 19.98060  1.000 35.90067  ? 254 PHE A CZ  1 
ATOM   1742 N  N   . PHE A 1 256 ? -43.12552 -131.00059 15.24585  1.000 32.13013  ? 255 PHE A N   1 
ATOM   1743 C  CA  . PHE A 1 256 ? -44.36797 -131.74043 15.03169  1.000 34.94679  ? 255 PHE A CA  1 
ATOM   1744 C  C   . PHE A 1 256 ? -45.07650 -131.95541 16.36047  1.000 34.06966  ? 255 PHE A C   1 
ATOM   1745 O  O   . PHE A 1 256 ? -44.54454 -132.61588 17.26258  1.000 36.93498  ? 255 PHE A O   1 
ATOM   1746 C  CB  . PHE A 1 256 ? -44.11347 -133.06645 14.31025  1.000 30.34674  ? 255 PHE A CB  1 
ATOM   1747 C  CG  . PHE A 1 256 ? -43.98332 -132.89309 12.83230  1.000 30.49433  ? 255 PHE A CG  1 
ATOM   1748 C  CD1 . PHE A 1 256 ? -45.11238 -132.92661 12.01542  1.000 34.04475  ? 255 PHE A CD1 1 
ATOM   1749 C  CD2 . PHE A 1 256 ? -42.75786 -132.62215 12.26116  1.000 33.43563  ? 255 PHE A CD2 1 
ATOM   1750 C  CE1 . PHE A 1 256 ? -45.00592 -132.72285 10.65632  1.000 31.72509  ? 255 PHE A CE1 1 
ATOM   1751 C  CE2 . PHE A 1 256 ? -42.65097 -132.42310 10.88494  1.000 32.84155  ? 255 PHE A CE2 1 
ATOM   1752 C  CZ  . PHE A 1 256 ? -43.77698 -132.47180 10.09257  1.000 33.92048  ? 255 PHE A CZ  1 
ATOM   1753 N  N   . ARG A 1 257 ? -46.27122 -131.39420 16.47215  1.000 34.94422  ? 256 ARG A N   1 
ATOM   1754 C  CA  . ARG A 1 257 ? -47.02524 -131.39314 17.71820  1.000 43.47575  ? 256 ARG A CA  1 
ATOM   1755 C  C   . ARG A 1 257 ? -47.95302 -132.59197 17.83573  1.000 39.42265  ? 256 ARG A C   1 
ATOM   1756 O  O   . ARG A 1 257 ? -48.60414 -132.76007 18.86929  1.000 43.89801  ? 256 ARG A O   1 
ATOM   1757 C  CB  . ARG A 1 257 ? -47.83743 -130.09159 17.82919  1.000 38.40317  ? 256 ARG A CB  1 
ATOM   1758 C  CG  . ARG A 1 257 ? -48.87653 -129.90251 16.71147  1.000 38.09483  ? 256 ARG A CG  1 
ATOM   1759 C  CD  . ARG A 1 257 ? -49.41253 -128.46642 16.71216  1.000 42.65385  ? 256 ARG A CD  1 
ATOM   1760 N  NE  . ARG A 1 257 ? -48.42221 -127.52210 16.19856  1.000 43.60895  ? 256 ARG A NE  1 
ATOM   1761 C  CZ  . ARG A 1 257 ? -48.56026 -126.20090 16.21408  1.000 47.73550  ? 256 ARG A CZ  1 
ATOM   1762 N  NH1 . ARG A 1 257 ? -49.64147 -125.62225 16.71893  1.000 42.83496  ? 256 ARG A NH1 1 
ATOM   1763 N  NH2 . ARG A 1 257 ? -47.57775 -125.44042 15.73807  1.000 40.61306  ? 256 ARG A NH2 1 
ATOM   1764 N  N   . GLN A 1 258 ? -48.04159 -133.40504 16.79039  1.000 35.44844  ? 257 GLN A N   1 
ATOM   1765 C  CA  . GLN A 1 258 ? -48.85158 -134.60671 16.78613  1.000 36.40235  ? 257 GLN A CA  1 
ATOM   1766 C  C   . GLN A 1 258 ? -48.02142 -135.71514 16.16718  1.000 32.24830  ? 257 GLN A C   1 
ATOM   1767 O  O   . GLN A 1 258 ? -47.02253 -135.45996 15.48735  1.000 32.15913  ? 257 GLN A O   1 
ATOM   1768 C  CB  . GLN A 1 258 ? -50.13960 -134.41950 15.96873  1.000 37.83906  ? 257 GLN A CB  1 
ATOM   1769 C  CG  . GLN A 1 258 ? -51.07480 -133.35560 16.49970  1.000 55.09633  ? 257 GLN A CG  1 
ATOM   1770 C  CD  . GLN A 1 258 ? -52.34248 -133.95035 17.07975  1.000 57.55451  ? 257 GLN A CD  1 
ATOM   1771 O  OE1 . GLN A 1 258 ? -52.55739 -135.16722 17.01735  1.000 57.70690  ? 257 GLN A OE1 1 
ATOM   1772 N  NE2 . GLN A 1 258 ? -53.19757 -133.09300 17.63722  1.000 59.00694  ? 257 GLN A NE2 1 
ATOM   1773 N  N   A ARG A 1 259 ? -48.45364 -136.95037 16.40172  0.499 32.97658  ? 258 ARG A N   1 
ATOM   1774 N  N   B ARG A 1 259 ? -48.44051 -136.95235 16.40431  0.501 32.97398  ? 258 ARG A N   1 
ATOM   1775 C  CA  A ARG A 1 259 ? -47.83053 -138.09754 15.75558  0.499 34.22254  ? 258 ARG A CA  1 
ATOM   1776 C  CA  B ARG A 1 259 ? -47.77161 -138.08288 15.77632  0.501 34.18298  ? 258 ARG A CA  1 
ATOM   1777 C  C   A ARG A 1 259 ? -48.00930 -138.00485 14.24586  0.499 33.95427  ? 258 ARG A C   1 
ATOM   1778 C  C   B ARG A 1 259 ? -47.99161 -138.01250 14.26829  0.501 33.95342  ? 258 ARG A C   1 
ATOM   1779 O  O   A ARG A 1 259 ? -49.13753 -138.00244 13.74532  0.499 33.61633  ? 258 ARG A O   1 
ATOM   1780 O  O   B ARG A 1 259 ? -49.13219 -138.02849 13.79450  0.501 33.62903  ? 258 ARG A O   1 
ATOM   1781 C  CB  A ARG A 1 259 ? -48.43780 -139.39628 16.28407  0.499 32.64402  ? 258 ARG A CB  1 
ATOM   1782 C  CB  B ARG A 1 259 ? -48.28567 -139.40190 16.35665  0.501 32.62445  ? 258 ARG A CB  1 
ATOM   1783 C  CG  A ARG A 1 259 ? -48.09722 -140.61021 15.42280  0.499 37.69224  ? 258 ARG A CG  1 
ATOM   1784 C  CG  B ARG A 1 259 ? -47.41764 -140.62841 16.01859  0.501 33.46555  ? 258 ARG A CG  1 
ATOM   1785 C  CD  A ARG A 1 259 ? -46.60822 -140.87863 15.46170  0.499 34.12389  ? 258 ARG A CD  1 
ATOM   1786 C  CD  B ARG A 1 259 ? -47.66706 -141.13961 14.58734  0.501 32.51967  ? 258 ARG A CD  1 
ATOM   1787 N  NE  A ARG A 1 259 ? -46.16124 -141.78258 14.40707  0.499 34.68035  ? 258 ARG A NE  1 
ATOM   1788 N  NE  B ARG A 1 259 ? -46.57933 -141.97574 14.09230  0.501 33.86411  ? 258 ARG A NE  1 
ATOM   1789 C  CZ  A ARG A 1 259 ? -45.00200 -142.42361 14.43823  0.499 33.30118  ? 258 ARG A CZ  1 
ATOM   1790 C  CZ  B ARG A 1 259 ? -46.60642 -142.63450 12.94149  0.501 38.22664  ? 258 ARG A CZ  1 
ATOM   1791 N  NH1 A ARG A 1 259 ? -44.16338 -142.27615 15.45205  0.499 30.80317  ? 258 ARG A NH1 1 
ATOM   1792 N  NH1 B ARG A 1 259 ? -47.66080 -142.58623 12.14111  0.501 29.01437  ? 258 ARG A NH1 1 
ATOM   1793 N  NH2 A ARG A 1 259 ? -44.68601 -143.24875 13.44056  0.499 33.19134  ? 258 ARG A NH2 1 
ATOM   1794 N  NH2 B ARG A 1 259 ? -45.55003 -143.36093 12.58525  0.501 34.35431  ? 258 ARG A NH2 1 
ATOM   1795 N  N   . VAL A 1 260 ? -46.89606 -137.93589 13.51751  1.000 32.14023  ? 259 VAL A N   1 
ATOM   1796 C  CA  . VAL A 1 260 ? -46.92076 -137.87834 12.05950  1.000 32.16129  ? 259 VAL A CA  1 
ATOM   1797 C  C   . VAL A 1 260 ? -45.85996 -138.84096 11.53135  1.000 34.87886  ? 259 VAL A C   1 
ATOM   1798 O  O   . VAL A 1 260 ? -44.73450 -138.86373 12.04069  1.000 34.47544  ? 259 VAL A O   1 
ATOM   1799 C  CB  . VAL A 1 260 ? -46.67951 -136.43898 11.54932  1.000 31.06957  ? 259 VAL A CB  1 
ATOM   1800 C  CG1 . VAL A 1 260 ? -46.53106 -136.41259 10.02179  1.000 28.23932  ? 259 VAL A CG1 1 
ATOM   1801 C  CG2 . VAL A 1 260 ? -47.84440 -135.50881 11.98784  1.000 26.59255  ? 259 VAL A CG2 1 
ATOM   1802 N  N   . SER A 1 261 ? -46.22063 -139.64287 10.52836  1.000 33.30707  ? 260 SER A N   1 
ATOM   1803 C  CA  . SER A 1 261 ? -45.30506 -140.66537 10.00314  1.000 30.55212  ? 260 SER A CA  1 
ATOM   1804 C  C   . SER A 1 261 ? -44.02363 -140.00680 9.49182   1.000 32.25399  ? 260 SER A C   1 
ATOM   1805 O  O   . SER A 1 261 ? -44.01583 -138.82710 9.14613   1.000 29.50495  ? 260 SER A O   1 
ATOM   1806 C  CB  . SER A 1 261 ? -45.96611 -141.48958 8.88100   1.000 32.21913  ? 260 SER A CB  1 
ATOM   1807 O  OG  . SER A 1 261 ? -46.16352 -140.70082 7.70726   1.000 33.68831  ? 260 SER A OG  1 
HETATM 1808 N  N   . SEP A 1 262 ? -42.94032 -140.77541 9.47429   1.000 35.81195  ? 261 SEP A N   1 
HETATM 1809 C  CA  . SEP A 1 262 ? -41.64992 -140.28674 9.01094   1.000 34.06378  ? 261 SEP A CA  1 
HETATM 1810 C  CB  . SEP A 1 262 ? -40.58390 -141.36858 9.22510   1.000 35.57253  ? 261 SEP A CB  1 
HETATM 1811 O  OG  . SEP A 1 262 ? -40.41976 -141.60015 10.61530  1.000 41.53337  ? 261 SEP A OG  1 
HETATM 1812 C  C   . SEP A 1 262 ? -41.70742 -139.86085 7.53144   1.000 32.56097  ? 261 SEP A C   1 
HETATM 1813 O  O   . SEP A 1 262 ? -41.10119 -138.86582 7.14750   1.000 30.89345  ? 261 SEP A O   1 
HETATM 1814 P  P   . SEP A 1 262 ? -40.88012 -143.08142 11.09270  0.575 43.59523  ? 261 SEP A P   1 
HETATM 1815 O  O1P . SEP A 1 262 ? -40.64105 -143.17580 12.68753  0.575 32.42326  ? 261 SEP A O1P 1 
HETATM 1816 O  O2P . SEP A 1 262 ? -42.43349 -143.36338 10.66665  0.575 34.05302  ? 261 SEP A O2P 1 
HETATM 1817 O  O3P . SEP A 1 262 ? -39.96393 -144.18250 10.37907  0.575 37.24449  ? 261 SEP A O3P 1 
ATOM   1818 N  N   . GLU A 1 263 ? -42.44169 -140.60712 6.71371   1.000 31.90670  ? 262 GLU A N   1 
ATOM   1819 C  CA  . GLU A 1 263 ? -42.57857 -140.25736 5.29332   1.000 33.11347  ? 262 GLU A CA  1 
ATOM   1820 C  C   . GLU A 1 263 ? -43.33432 -138.93176 5.13487   1.000 30.30338  ? 262 GLU A C   1 
ATOM   1821 O  O   . GLU A 1 263 ? -42.98528 -138.09206 4.29894   1.000 31.81568  ? 262 GLU A O   1 
ATOM   1822 C  CB  . GLU A 1 263 ? -43.28538 -141.38301 4.52586   1.000 31.99901  ? 262 GLU A CB  1 
ATOM   1823 C  CG  . GLU A 1 263 ? -42.62217 -142.75267 4.70463   1.000 46.94792  ? 262 GLU A CG  1 
ATOM   1824 C  CD  . GLU A 1 263 ? -43.25038 -143.60900 5.82929   1.000 51.17948  ? 262 GLU A CD  1 
ATOM   1825 O  OE2 . GLU A 1 263 ? -43.18781 -143.25257 7.03816   1.000 39.04077  ? 262 GLU A OE2 1 
ATOM   1826 N  N   . CYS A 1 264 ? -44.37285 -138.73710 5.94971   1.000 31.44693  ? 263 CYS A N   1 
ATOM   1827 C  CA  . CYS A 1 264 ? -45.11778 -137.47891 5.88602   1.000 29.54944  ? 263 CYS A CA  1 
ATOM   1828 C  C   . CYS A 1 264 ? -44.28381 -136.30919 6.41126   1.000 33.63317  ? 263 CYS A C   1 
ATOM   1829 O  O   . CYS A 1 264 ? -44.26986 -135.23121 5.80560   1.000 29.01069  ? 263 CYS A O   1 
ATOM   1830 C  CB  . CYS A 1 264 ? -46.42706 -137.59618 6.67222   1.000 30.46019  ? 263 CYS A CB  1 
ATOM   1831 S  SG  . CYS A 1 264 ? -47.50439 -136.16581 6.45374   1.000 34.37395  ? 263 CYS A SG  1 
ATOM   1832 N  N   . GLN A 1 265 ? -43.59203 -136.49673 7.54291   1.000 27.35435  ? 264 GLN A N   1 
ATOM   1833 C  CA  . GLN A 1 265 ? -42.67732 -135.46072 8.02857   1.000 30.03267  ? 264 GLN A CA  1 
ATOM   1834 C  C   . GLN A 1 265 ? -41.66031 -135.07657 6.95620   1.000 30.31402  ? 264 GLN A C   1 
ATOM   1835 O  O   . GLN A 1 265 ? -41.34340 -133.89595 6.78077   1.000 31.55135  ? 264 GLN A O   1 
ATOM   1836 C  CB  . GLN A 1 265 ? -41.94187 -135.94482 9.28130   1.000 28.62222  ? 264 GLN A CB  1 
ATOM   1837 C  CG  . GLN A 1 265 ? -42.78931 -135.99037 10.57291  1.000 33.33049  ? 264 GLN A CG  1 
ATOM   1838 C  CD  . GLN A 1 265 ? -41.93133 -136.08732 11.82924  1.000 36.10554  ? 264 GLN A CD  1 
ATOM   1839 O  OE1 . GLN A 1 265 ? -40.72528 -135.86701 11.78503  1.000 39.06357  ? 264 GLN A OE1 1 
ATOM   1840 N  NE2 . GLN A 1 265 ? -42.56006 -136.38934 12.96008  1.000 32.71840  ? 264 GLN A NE2 1 
ATOM   1841 N  N   . HIS A 1 266 ? -41.12898 -136.06832 6.23807   1.000 28.99003  ? 265 HIS A N   1 
ATOM   1842 C  CA  . HIS A 1 266 ? -40.11256 -135.77780 5.23178   1.000 31.76064  ? 265 HIS A CA  1 
ATOM   1843 C  C   . HIS A 1 266 ? -40.67736 -134.88621 4.12750   1.000 29.33111  ? 265 HIS A C   1 
ATOM   1844 O  O   . HIS A 1 266 ? -40.06660 -133.87551 3.74908   1.000 29.94417  ? 265 HIS A O   1 
ATOM   1845 C  CB  . HIS A 1 266 ? -39.55361 -137.08552 4.65675   1.000 30.92954  ? 265 HIS A CB  1 
ATOM   1846 C  CG  . HIS A 1 266 ? -38.57932 -136.87949 3.53807   1.000 33.02810  ? 265 HIS A CG  1 
ATOM   1847 N  ND1 . HIS A 1 266 ? -38.97536 -136.74069 2.22725   1.000 36.68061  ? 265 HIS A ND1 1 
ATOM   1848 C  CD2 . HIS A 1 266 ? -37.22877 -136.76095 3.53755   1.000 39.36266  ? 265 HIS A CD2 1 
ATOM   1849 C  CE1 . HIS A 1 266 ? -37.91225 -136.55576 1.46195   1.000 35.69515  ? 265 HIS A CE1 1 
ATOM   1850 N  NE2 . HIS A 1 266 ? -36.83907 -136.56560 2.23367   1.000 35.32700  ? 265 HIS A NE2 1 
ATOM   1851 N  N   . LEU A 1 267 ? -41.85520 -135.23734 3.60891   1.000 29.60090  ? 266 LEU A N   1 
ATOM   1852 C  CA  . LEU A 1 267 ? -42.48339 -134.42475 2.56651   1.000 27.73677  ? 266 LEU A CA  1 
ATOM   1853 C  C   . LEU A 1 267 ? -42.73547 -132.99957 3.04626   1.000 26.50034  ? 266 LEU A C   1 
ATOM   1854 O  O   . LEU A 1 267 ? -42.44305 -132.03030 2.33268   1.000 28.35630  ? 266 LEU A O   1 
ATOM   1855 C  CB  . LEU A 1 267 ? -43.79942 -135.06675 2.11707   1.000 25.52455  ? 266 LEU A CB  1 
ATOM   1856 C  CG  . LEU A 1 267 ? -44.59588 -134.28980 1.06205   1.000 30.96741  ? 266 LEU A CG  1 
ATOM   1857 C  CD1 . LEU A 1 267 ? -43.75175 -134.00349 -0.21616  1.000 25.57224  ? 266 LEU A CD1 1 
ATOM   1858 C  CD2 . LEU A 1 267 ? -45.87312 -135.05881 0.68531   1.000 28.96968  ? 266 LEU A CD2 1 
ATOM   1859 N  N   . ILE A 1 268 ? -43.33422 -132.85672 4.23252   1.000 28.91633  ? 267 ILE A N   1 
ATOM   1860 C  CA  . ILE A 1 268 ? -43.58037 -131.52777 4.79179   1.000 26.50464  ? 267 ILE A CA  1 
ATOM   1861 C  C   . ILE A 1 268 ? -42.28225 -130.73630 4.87879   1.000 29.69419  ? 267 ILE A C   1 
ATOM   1862 O  O   . ILE A 1 268 ? -42.20895 -129.58424 4.43969   1.000 28.05902  ? 267 ILE A O   1 
ATOM   1863 C  CB  . ILE A 1 268 ? -44.25905 -131.64112 6.16609   1.000 28.30069  ? 267 ILE A CB  1 
ATOM   1864 C  CG1 . ILE A 1 268 ? -45.68466 -132.16369 5.99362   1.000 28.85570  ? 267 ILE A CG1 1 
ATOM   1865 C  CG2 . ILE A 1 268 ? -44.24116 -130.27914 6.91516   1.000 28.19271  ? 267 ILE A CG2 1 
ATOM   1866 C  CD1 . ILE A 1 268 ? -46.35341 -132.54949 7.32045   1.000 26.79637  ? 267 ILE A CD1 1 
ATOM   1867 N  N   . ARG A 1 269 ? -41.23646 -131.33932 5.44499   1.000 29.18896  ? 268 ARG A N   1 
ATOM   1868 C  CA  . ARG A 1 269 ? -39.99345 -130.58625 5.62885   1.000 32.28613  ? 268 ARG A CA  1 
ATOM   1869 C  C   . ARG A 1 269 ? -39.34852 -130.22919 4.29982   1.000 33.21635  ? 268 ARG A C   1 
ATOM   1870 O  O   . ARG A 1 269 ? -38.66160 -129.20266 4.19904   1.000 31.59411  ? 268 ARG A O   1 
ATOM   1871 C  CB  . ARG A 1 269 ? -39.00859 -131.38166 6.48886   1.000 33.53272  ? 268 ARG A CB  1 
ATOM   1872 C  CG  . ARG A 1 269 ? -39.36939 -131.37357 7.97319   1.000 29.34247  ? 268 ARG A CG  1 
ATOM   1873 C  CD  . ARG A 1 269 ? -38.17293 -131.75135 8.83034   1.000 41.65024  ? 268 ARG A CD  1 
ATOM   1874 N  NE  . ARG A 1 269 ? -38.48695 -131.63394 10.25092  1.000 50.11300  ? 268 ARG A NE  1 
ATOM   1875 C  CZ  . ARG A 1 269 ? -38.90755 -132.64846 10.99163  1.000 46.86125  ? 268 ARG A CZ  1 
ATOM   1876 N  NH1 . ARG A 1 269 ? -39.02913 -133.86645 10.48305  1.000 38.08954  ? 268 ARG A NH1 1 
ATOM   1877 N  NH2 . ARG A 1 269 ? -39.21414 -132.43616 12.26867  1.000 42.53962  ? 268 ARG A NH2 1 
ATOM   1878 N  N   . TRP A 1 270 ? -39.55745 -131.06490 3.27951   1.000 30.18300  ? 269 TRP A N   1 
ATOM   1879 C  CA  . TRP A 1 270 ? -39.05277 -130.77211 1.93946   1.000 29.65364  ? 269 TRP A CA  1 
ATOM   1880 C  C   . TRP A 1 270 ? -39.81377 -129.60089 1.31521   1.000 30.92791  ? 269 TRP A C   1 
ATOM   1881 O  O   . TRP A 1 270 ? -39.20458 -128.67933 0.77327   1.000 29.07020  ? 269 TRP A O   1 
ATOM   1882 C  CB  . TRP A 1 270 ? -39.15847 -132.03624 1.07723   1.000 27.76666  ? 269 TRP A CB  1 
ATOM   1883 C  CG  . TRP A 1 270 ? -38.37265 -132.03140 -0.19681  1.000 27.23256  ? 269 TRP A CG  1 
ATOM   1884 C  CD1 . TRP A 1 270 ? -37.42231 -131.12498 -0.57844  1.000 31.71292  ? 269 TRP A CD1 1 
ATOM   1885 C  CD2 . TRP A 1 270 ? -38.46838 -132.98922 -1.26462  1.000 31.66508  ? 269 TRP A CD2 1 
ATOM   1886 N  NE1 . TRP A 1 270 ? -36.93489 -131.45024 -1.82253  1.000 33.14206  ? 269 TRP A NE1 1 
ATOM   1887 C  CE2 . TRP A 1 270 ? -37.55918 -132.58829 -2.26737  1.000 31.15087  ? 269 TRP A CE2 1 
ATOM   1888 C  CE3 . TRP A 1 270 ? -39.25180 -134.13425 -1.47759  1.000 33.24052  ? 269 TRP A CE3 1 
ATOM   1889 C  CZ2 . TRP A 1 270 ? -37.38565 -133.30959 -3.46544  1.000 34.59365  ? 269 TRP A CZ2 1 
ATOM   1890 C  CZ3 . TRP A 1 270 ? -39.08492 -134.85375 -2.67120  1.000 38.40984  ? 269 TRP A CZ3 1 
ATOM   1891 C  CH2 . TRP A 1 270 ? -38.14972 -134.43669 -3.64696  1.000 30.95816  ? 269 TRP A CH2 1 
ATOM   1892 N  N   . CYS A 1 271 ? -41.15010 -129.59799 1.42351   1.000 28.13995  ? 270 CYS A N   1 
ATOM   1893 C  CA  . CYS A 1 271 ? -41.94593 -128.46352 0.94207   1.000 28.93058  ? 270 CYS A CA  1 
ATOM   1894 C  C   . CYS A 1 271 ? -41.58685 -127.17093 1.65600   1.000 28.83469  ? 270 CYS A C   1 
ATOM   1895 O  O   . CYS A 1 271 ? -41.71521 -126.08113 1.07636   1.000 29.25781  ? 270 CYS A O   1 
ATOM   1896 C  CB  . CYS A 1 271 ? -43.44957 -128.73001 1.13893   1.000 28.08902  ? 270 CYS A CB  1 
ATOM   1897 S  SG  . CYS A 1 271 ? -44.10722 -130.04647 0.07608   1.000 30.88386  ? 270 CYS A SG  1 
ATOM   1898 N  N   . LEU A 1 272 ? -41.17653 -127.26360 2.92176   1.000 28.12191  ? 271 LEU A N   1 
ATOM   1899 C  CA  . LEU A 1 272 ? -40.81492 -126.09407 3.71419   1.000 31.95739  ? 271 LEU A CA  1 
ATOM   1900 C  C   . LEU A 1 272 ? -39.30978 -125.87132 3.75708   1.000 32.71414  ? 271 LEU A C   1 
ATOM   1901 O  O   . LEU A 1 272 ? -38.79292 -125.29459 4.71855   1.000 30.36053  ? 271 LEU A O   1 
ATOM   1902 C  CB  . LEU A 1 272 ? -41.38315 -126.22088 5.12703   1.000 32.05817  ? 271 LEU A CB  1 
ATOM   1903 C  CG  . LEU A 1 272 ? -42.90344 -126.35619 5.18598   1.000 26.61263  ? 271 LEU A CG  1 
ATOM   1904 C  CD1 . LEU A 1 272 ? -43.39077 -126.52289 6.68263   1.000 27.78342  ? 271 LEU A CD1 1 
ATOM   1905 C  CD2 . LEU A 1 272 ? -43.56858 -125.13891 4.53740   1.000 25.36386  ? 271 LEU A CD2 1 
ATOM   1906 N  N   . ALA A 1 273 ? -38.58935 -126.31924 2.73398   1.000 32.81084  ? 272 ALA A N   1 
ATOM   1907 C  CA  . ALA A 1 273 ? -37.19257 -125.92823 2.60429   1.000 34.88221  ? 272 ALA A CA  1 
ATOM   1908 C  C   . ALA A 1 273 ? -37.09227 -124.40639 2.54548   1.000 36.13926  ? 272 ALA A C   1 
ATOM   1909 O  O   . ALA A 1 273 ? -37.85229 -123.75349 1.82577   1.000 32.36677  ? 272 ALA A O   1 
ATOM   1910 C  CB  . ALA A 1 273 ? -36.58542 -126.55304 1.34567   1.000 31.87928  ? 272 ALA A CB  1 
ATOM   1911 N  N   . LEU A 1 274 ? -36.14967 -123.83679 3.30115   1.000 33.44635  ? 273 LEU A N   1 
ATOM   1912 C  CA  . LEU A 1 274 ? -36.00964 -122.37908 3.32803   1.000 32.93629  ? 273 LEU A CA  1 
ATOM   1913 C  C   . LEU A 1 274 ? -35.63634 -121.82346 1.95456   1.000 35.32548  ? 273 LEU A C   1 
ATOM   1914 O  O   . LEU A 1 274 ? -36.17107 -120.79219 1.52791   1.000 37.07597  ? 273 LEU A O   1 
ATOM   1915 C  CB  . LEU A 1 274 ? -34.96067 -121.96433 4.36203   1.000 38.59147  ? 273 LEU A CB  1 
ATOM   1916 C  CG  . LEU A 1 274 ? -35.33223 -122.05061 5.84709   1.000 36.54694  ? 273 LEU A CG  1 
ATOM   1917 C  CD1 . LEU A 1 274 ? -34.12615 -121.67058 6.70744   1.000 41.96210  ? 273 LEU A CD1 1 
ATOM   1918 C  CD2 . LEU A 1 274 ? -36.53164 -121.16576 6.16791   1.000 36.87110  ? 273 LEU A CD2 1 
ATOM   1919 N  N   . ARG A 1 275 ? -34.69876 -122.48055 1.24969   1.000 36.32540  ? 274 ARG A N   1 
ATOM   1920 C  CA  . ARG A 1 275 ? -34.36646 -121.94853 -0.07104  1.000 38.91351  ? 274 ARG A CA  1 
ATOM   1921 C  C   . ARG A 1 275 ? -35.30981 -122.52425 -1.11736  1.000 35.58514  ? 274 ARG A C   1 
ATOM   1922 O  O   . ARG A 1 275 ? -35.49783 -123.74402 -1.16379  1.000 32.78834  ? 274 ARG A O   1 
ATOM   1923 C  CB  . ARG A 1 275 ? -32.92784 -122.26980 -0.45052  1.000 39.31064  ? 274 ARG A CB  1 
ATOM   1924 C  CG  . ARG A 1 275 ? -31.89439 -121.63308 0.48040   1.000 47.32607  ? 274 ARG A CG  1 
ATOM   1925 N  N   . PRO A 1 276 ? -35.89398 -121.67898 -1.97075  1.000 34.31374  ? 275 PRO A N   1 
ATOM   1926 C  CA  . PRO A 1 276 ? -36.90141 -122.17216 -2.92971  1.000 35.93905  ? 275 PRO A CA  1 
ATOM   1927 C  C   . PRO A 1 276 ? -36.40643 -123.27447 -3.84473  1.000 35.02182  ? 275 PRO A C   1 
ATOM   1928 O  O   . PRO A 1 276 ? -37.17041 -124.19634 -4.15578  1.000 36.45279  ? 275 PRO A O   1 
ATOM   1929 C  CB  . PRO A 1 276 ? -37.26764 -120.91004 -3.72902  1.000 38.01862  ? 275 PRO A CB  1 
ATOM   1930 C  CG  . PRO A 1 276 ? -36.91663 -119.77351 -2.82015  1.000 44.54529  ? 275 PRO A CG  1 
ATOM   1931 C  CD  . PRO A 1 276 ? -35.74833 -120.21333 -2.00194  1.000 36.34405  ? 275 PRO A CD  1 
ATOM   1932 N  N   A SER A 1 277 ? -35.15047 -123.19682 -4.29296  0.404 35.37491  ? 276 SER A N   1 
ATOM   1933 N  N   B SER A 1 277 ? -35.15638 -123.20391 -4.31075  0.596 35.33057  ? 276 SER A N   1 
ATOM   1934 C  CA  A SER A 1 277 ? -34.59798 -124.22464 -5.16550  0.404 34.36440  ? 276 SER A CA  1 
ATOM   1935 C  CA  B SER A 1 277 ? -34.64760 -124.25343 -5.18737  0.596 34.30515  ? 276 SER A CA  1 
ATOM   1936 C  C   A SER A 1 277 ? -34.52484 -125.58693 -4.48980  0.404 36.54675  ? 276 SER A C   1 
ATOM   1937 C  C   B SER A 1 277 ? -34.50578 -125.59679 -4.48870  0.596 36.54967  ? 276 SER A C   1 
ATOM   1938 O  O   A SER A 1 277 ? -34.43613 -126.60185 -5.18834  0.404 35.98328  ? 276 SER A O   1 
ATOM   1939 O  O   B SER A 1 277 ? -34.32932 -126.60873 -5.17473  0.596 35.95735  ? 276 SER A O   1 
ATOM   1940 C  CB  A SER A 1 277 ? -33.20341 -123.81220 -5.64518  0.404 37.54125  ? 276 SER A CB  1 
ATOM   1941 C  CB  B SER A 1 277 ? -33.29099 -123.85976 -5.77621  0.596 37.42559  ? 276 SER A CB  1 
ATOM   1942 O  OG  A SER A 1 277 ? -32.32299 -123.62272 -4.54586  0.404 34.82610  ? 276 SER A OG  1 
ATOM   1943 O  OG  B SER A 1 277 ? -33.40712 -122.74117 -6.62656  0.596 39.75002  ? 276 SER A OG  1 
ATOM   1944 N  N   . ASP A 1 278 ? -34.56318 -125.63755 -3.15499  1.000 33.33667  ? 277 ASP A N   1 
ATOM   1945 C  CA  . ASP A 1 278 ? -34.47041 -126.90388 -2.43489  1.000 33.30435  ? 277 ASP A CA  1 
ATOM   1946 C  C   . ASP A 1 278 ? -35.81869 -127.58614 -2.24633  1.000 35.04738  ? 277 ASP A C   1 
ATOM   1947 O  O   . ASP A 1 278 ? -35.85506 -128.70400 -1.71615  1.000 34.76815  ? 277 ASP A O   1 
ATOM   1948 C  CB  . ASP A 1 278 ? -33.82826 -126.70812 -1.05301  1.000 29.99832  ? 277 ASP A CB  1 
ATOM   1949 C  CG  . ASP A 1 278 ? -32.34373 -126.33581 -1.12907  1.000 43.18740  ? 277 ASP A CG  1 
ATOM   1950 O  OD1 . ASP A 1 278 ? -31.66026 -126.71140 -2.10204  1.000 38.77542  ? 277 ASP A OD1 1 
ATOM   1951 O  OD2 . ASP A 1 278 ? -31.86211 -125.66615 -0.19377  1.000 40.54239  ? 277 ASP A OD2 1 
ATOM   1952 N  N   . ARG A 1 279 ? -36.93455 -126.92830 -2.64267  1.000 29.00644  ? 278 ARG A N   1 
ATOM   1953 C  CA  . ARG A 1 279 ? -38.27123 -127.49037 -2.52409  1.000 30.74767  ? 278 ARG A CA  1 
ATOM   1954 C  C   . ARG A 1 279 ? -38.55881 -128.44080 -3.68682  1.000 35.10532  ? 278 ARG A C   1 
ATOM   1955 O  O   . ARG A 1 279 ? -37.97926 -128.30298 -4.76959  1.000 33.32720  ? 278 ARG A O   1 
ATOM   1956 C  CB  . ARG A 1 279 ? -39.31784 -126.37157 -2.49328  1.000 26.93266  ? 278 ARG A CB  1 
ATOM   1957 C  CG  . ARG A 1 279 ? -39.22294 -125.52898 -1.21098  1.000 36.28538  ? 278 ARG A CG  1 
ATOM   1958 C  CD  . ARG A 1 279 ? -40.10401 -124.27035 -1.21449  1.000 31.53475  ? 278 ARG A CD  1 
ATOM   1959 N  NE  . ARG A 1 279 ? -39.53765 -123.29083 -0.29276  1.000 30.18876  ? 278 ARG A NE  1 
ATOM   1960 C  CZ  . ARG A 1 279 ? -39.62237 -121.97769 -0.45075  1.000 32.61914  ? 278 ARG A CZ  1 
ATOM   1961 N  NH1 . ARG A 1 279 ? -40.34910 -121.44223 -1.42895  1.000 27.66612  ? 278 ARG A NH1 1 
ATOM   1962 N  NH2 . ARG A 1 279 ? -38.93894 -121.18289 0.37195   1.000 30.23443  ? 278 ARG A NH2 1 
ATOM   1963 N  N   . PRO A 1 280 ? -39.44607 -129.41180 -3.48310  1.000 32.04357  ? 279 PRO A N   1 
ATOM   1964 C  CA  . PRO A 1 280 ? -39.80992 -130.32268 -4.57407  1.000 28.71125  ? 279 PRO A CA  1 
ATOM   1965 C  C   . PRO A 1 280 ? -40.64293 -129.59393 -5.60854  1.000 30.16678  ? 279 PRO A C   1 
ATOM   1966 O  O   . PRO A 1 280 ? -41.31640 -128.61110 -5.29966  1.000 30.07792  ? 279 PRO A O   1 
ATOM   1967 C  CB  . PRO A 1 280 ? -40.64965 -131.39472 -3.87298  1.000 29.16666  ? 279 PRO A CB  1 
ATOM   1968 C  CG  . PRO A 1 280 ? -41.30276 -130.62518 -2.73751  1.000 30.86724  ? 279 PRO A CG  1 
ATOM   1969 C  CD  . PRO A 1 280 ? -40.25806 -129.64289 -2.27289  1.000 29.50499  ? 279 PRO A CD  1 
ATOM   1970 N  N   . THR A 1 281 ? -40.58777 -130.08909 -6.84539  1.000 28.93650  ? 280 THR A N   1 
ATOM   1971 C  CA  . THR A 1 281 ? -41.59128 -129.74646 -7.84415  1.000 31.08426  ? 280 THR A CA  1 
ATOM   1972 C  C   . THR A 1 281 ? -42.90738 -130.46217 -7.53437  1.000 33.80502  ? 280 THR A C   1 
ATOM   1973 O  O   . THR A 1 281 ? -42.96776 -131.36583 -6.69975  1.000 32.60044  ? 280 THR A O   1 
ATOM   1974 C  CB  . THR A 1 281 ? -41.12621 -130.15429 -9.23938  1.000 33.84249  ? 280 THR A CB  1 
ATOM   1975 O  OG1 . THR A 1 281 ? -40.99379 -131.58572 -9.28537  1.000 33.09036  ? 280 THR A OG1 1 
ATOM   1976 C  CG2 . THR A 1 281 ? -39.76511 -129.50441 -9.58771  1.000 33.11451  ? 280 THR A CG2 1 
ATOM   1977 N  N   . PHE A 1 282 ? -43.97639 -130.07588 -8.24878  1.000 30.08868  ? 281 PHE A N   1 
ATOM   1978 C  CA  . PHE A 1 282 ? -45.24043 -130.79023 -8.07311  1.000 32.17794  ? 281 PHE A CA  1 
ATOM   1979 C  C   . PHE A 1 282 ? -45.09660 -132.25567 -8.45888  1.000 35.21464  ? 281 PHE A C   1 
ATOM   1980 O  O   . PHE A 1 282 ? -45.68768 -133.13863 -7.82548  1.000 29.90521  ? 281 PHE A O   1 
ATOM   1981 C  CB  . PHE A 1 282 ? -46.34651 -130.11135 -8.88860  1.000 30.68689  ? 281 PHE A CB  1 
ATOM   1982 C  CG  . PHE A 1 282 ? -46.88294 -128.87784 -8.23068  1.000 29.72909  ? 281 PHE A CG  1 
ATOM   1983 C  CD1 . PHE A 1 282 ? -46.16910 -127.69473 -8.27140  1.000 36.59674  ? 281 PHE A CD1 1 
ATOM   1984 C  CD2 . PHE A 1 282 ? -48.08105 -128.90549 -7.54008  1.000 35.59852  ? 281 PHE A CD2 1 
ATOM   1985 C  CE1 . PHE A 1 282 ? -46.65282 -126.54740 -7.66139  1.000 41.60905  ? 281 PHE A CE1 1 
ATOM   1986 C  CE2 . PHE A 1 282 ? -48.56765 -127.76140 -6.91127  1.000 39.74294  ? 281 PHE A CE2 1 
ATOM   1987 C  CZ  . PHE A 1 282 ? -47.84837 -126.58332 -6.97249  1.000 38.93083  ? 281 PHE A CZ  1 
ATOM   1988 N  N   . GLU A 1 283 ? -44.31083 -132.53317 -9.49917  1.000 31.83974  ? 282 GLU A N   1 
ATOM   1989 C  CA  . GLU A 1 283 ? -44.06108 -133.91748 -9.88337  1.000 31.61764  ? 282 GLU A CA  1 
ATOM   1990 C  C   . GLU A 1 283 ? -43.40911 -134.69047 -8.74711  1.000 34.43746  ? 282 GLU A C   1 
ATOM   1991 O  O   . GLU A 1 283 ? -43.81279 -135.82254 -8.44432  1.000 31.81498  ? 282 GLU A O   1 
ATOM   1992 C  CB  . GLU A 1 283 ? -43.17824 -133.96192 -11.13465 1.000 30.67335  ? 282 GLU A CB  1 
ATOM   1993 C  CG  . GLU A 1 283 ? -42.67995 -135.36200 -11.45985 1.000 31.84679  ? 282 GLU A CG  1 
ATOM   1994 C  CD  . GLU A 1 283 ? -41.93303 -135.41367 -12.78329 1.000 43.37579  ? 282 GLU A CD  1 
ATOM   1995 O  OE1 . GLU A 1 283 ? -41.40830 -134.36589 -13.21010 1.000 46.09321  ? 282 GLU A OE1 1 
ATOM   1996 O  OE2 . GLU A 1 283 ? -41.87630 -136.49957 -13.39259 1.000 44.46356  ? 282 GLU A OE2 1 
ATOM   1997 N  N   . GLU A 1 284 ? -42.41477 -134.07967 -8.08506  1.000 29.36326  ? 283 GLU A N   1 
ATOM   1998 C  CA  . GLU A 1 284 ? -41.73528 -134.75174 -6.98156  1.000 30.85060  ? 283 GLU A CA  1 
ATOM   1999 C  C   . GLU A 1 284 ? -42.65641 -134.92688 -5.77775  1.000 30.88256  ? 283 GLU A C   1 
ATOM   2000 O  O   . GLU A 1 284 ? -42.57691 -135.94159 -5.07620  1.000 30.24028  ? 283 GLU A O   1 
ATOM   2001 C  CB  . GLU A 1 284 ? -40.47291 -133.97775 -6.58458  1.000 33.12015  ? 283 GLU A CB  1 
ATOM   2002 C  CG  . GLU A 1 284 ? -39.34131 -134.06232 -7.63752  1.000 36.22729  ? 283 GLU A CG  1 
ATOM   2003 C  CD  . GLU A 1 284 ? -38.13691 -133.19932 -7.26596  1.000 38.72778  ? 283 GLU A CD  1 
ATOM   2004 O  OE1 . GLU A 1 284 ? -38.32108 -132.00115 -6.98650  1.000 34.23601  ? 283 GLU A OE1 1 
ATOM   2005 O  OE2 . GLU A 1 284 ? -37.01218 -133.73086 -7.22990  1.000 43.97635  ? 283 GLU A OE2 1 
ATOM   2006 N  N   . ILE A 1 285 ? -43.52827 -133.95383 -5.50698  1.000 28.74610  ? 284 ILE A N   1 
ATOM   2007 C  CA  . ILE A 1 285 ? -44.49760 -134.14560 -4.42155  1.000 28.70594  ? 284 ILE A CA  1 
ATOM   2008 C  C   . ILE A 1 285 ? -45.37188 -135.36313 -4.70625  1.000 29.80149  ? 284 ILE A C   1 
ATOM   2009 O  O   . ILE A 1 285 ? -45.54465 -136.24586 -3.86168  1.000 29.34927  ? 284 ILE A O   1 
ATOM   2010 C  CB  . ILE A 1 285 ? -45.35976 -132.88165 -4.23107  1.000 30.05762  ? 284 ILE A CB  1 
ATOM   2011 C  CG1 . ILE A 1 285 ? -44.49045 -131.68214 -3.83188  1.000 28.80674  ? 284 ILE A CG1 1 
ATOM   2012 C  CG2 . ILE A 1 285 ? -46.47860 -133.16416 -3.19775  1.000 29.47688  ? 284 ILE A CG2 1 
ATOM   2013 C  CD1 . ILE A 1 285 ? -45.26369 -130.34353 -3.77080  1.000 32.83884  ? 284 ILE A CD1 1 
ATOM   2014 N  N   . GLN A 1 286 ? -45.94717 -135.42173 -5.90844  1.000 27.02053  ? 285 GLN A N   1 
ATOM   2015 C  CA  . GLN A 1 286 ? -46.90131 -136.48263 -6.20101  1.000 28.39338  ? 285 GLN A CA  1 
ATOM   2016 C  C   . GLN A 1 286 ? -46.22920 -137.83640 -6.39275  1.000 33.23325  ? 285 GLN A C   1 
ATOM   2017 O  O   . GLN A 1 286 ? -46.89704 -138.86230 -6.22830  1.000 33.66098  ? 285 GLN A O   1 
ATOM   2018 C  CB  . GLN A 1 286 ? -47.73578 -136.09195 -7.42165  1.000 28.23373  ? 285 GLN A CB  1 
ATOM   2019 C  CG  . GLN A 1 286 ? -48.75406 -134.99993 -7.08686  1.000 28.23231  ? 285 GLN A CG  1 
ATOM   2020 C  CD  . GLN A 1 286 ? -49.74594 -134.75328 -8.20260  1.000 31.46131  ? 285 GLN A CD  1 
ATOM   2021 O  OE1 . GLN A 1 286 ? -49.36245 -134.39141 -9.30774  1.000 31.27221  ? 285 GLN A OE1 1 
ATOM   2022 N  NE2 . GLN A 1 286 ? -51.03372 -134.96232 -7.91769  1.000 31.64730  ? 285 GLN A NE2 1 
ATOM   2023 N  N   . ASN A 1 287 ? -44.92388 -137.87573 -6.69137  1.000 27.73663  ? 286 ASN A N   1 
ATOM   2024 C  CA  . ASN A 1 287 ? -44.19118 -139.14062 -6.68630  1.000 32.07570  ? 286 ASN A CA  1 
ATOM   2025 C  C   . ASN A 1 287 ? -43.61995 -139.49806 -5.32292  1.000 35.07255  ? 286 ASN A C   1 
ATOM   2026 O  O   . ASN A 1 287 ? -42.95407 -140.52989 -5.20202  1.000 32.84599  ? 286 ASN A O   1 
ATOM   2027 C  CB  . ASN A 1 287 ? -43.04649 -139.12010 -7.70640  1.000 34.80022  ? 286 ASN A CB  1 
ATOM   2028 C  CG  . ASN A 1 287 ? -43.53439 -139.21595 -9.12382  1.000 37.71866  ? 286 ASN A CG  1 
ATOM   2029 O  OD1 . ASN A 1 287 ? -44.56643 -139.82091 -9.38385  1.000 38.15418  ? 286 ASN A OD1 1 
ATOM   2030 N  ND2 . ASN A 1 287 ? -42.79362 -138.61145 -10.05713 1.000 35.93649  ? 286 ASN A ND2 1 
ATOM   2031 N  N   . HIS A 1 288 ? -43.83875 -138.67209 -4.30153  1.000 32.51962  ? 287 HIS A N   1 
ATOM   2032 C  CA  . HIS A 1 288 ? -43.26913 -138.95698 -2.98871  1.000 33.34195  ? 287 HIS A CA  1 
ATOM   2033 C  C   . HIS A 1 288 ? -43.87917 -140.23747 -2.40598  1.000 30.29098  ? 287 HIS A C   1 
ATOM   2034 O  O   . HIS A 1 288 ? -45.05179 -140.53870 -2.64512  1.000 32.21966  ? 287 HIS A O   1 
ATOM   2035 C  CB  . HIS A 1 288 ? -43.51196 -137.77231 -2.05157  1.000 31.09359  ? 287 HIS A CB  1 
ATOM   2036 C  CG  . HIS A 1 288 ? -42.72099 -137.82494 -0.77502  1.000 31.59111  ? 287 HIS A CG  1 
ATOM   2037 N  ND1 . HIS A 1 288 ? -43.09817 -138.60080 0.30144   1.000 30.55467  ? 287 HIS A ND1 1 
ATOM   2038 C  CD2 . HIS A 1 288 ? -41.57601 -137.19799 -0.40352  1.000 30.25104  ? 287 HIS A CD2 1 
ATOM   2039 C  CE1 . HIS A 1 288 ? -42.21585 -138.46142 1.27768   1.000 32.01823  ? 287 HIS A CE1 1 
ATOM   2040 N  NE2 . HIS A 1 288 ? -41.28372 -137.61115 0.87943   1.000 30.41464  ? 287 HIS A NE2 1 
ATOM   2041 N  N   . PRO A 1 289 ? -43.09953 -141.02479 -1.65429  1.000 32.76996  ? 288 PRO A N   1 
ATOM   2042 C  CA  . PRO A 1 289 ? -43.65451 -142.27114 -1.08753  1.000 35.52453  ? 288 PRO A CA  1 
ATOM   2043 C  C   . PRO A 1 289 ? -44.89118 -142.05578 -0.22648  1.000 33.45865  ? 288 PRO A C   1 
ATOM   2044 O  O   . PRO A 1 289 ? -45.79668 -142.90026 -0.23873  1.000 33.29613  ? 288 PRO A O   1 
ATOM   2045 C  CB  . PRO A 1 289 ? -42.48541 -142.83354 -0.26270  1.000 35.42120  ? 288 PRO A CB  1 
ATOM   2046 C  CG  . PRO A 1 289 ? -41.26480 -142.32640 -0.97451  1.000 44.01855  ? 288 PRO A CG  1 
ATOM   2047 C  CD  . PRO A 1 289 ? -41.63205 -140.96451 -1.53148  1.000 37.39603  ? 288 PRO A CD  1 
ATOM   2048 N  N   . TRP A 1 290 ? -44.98247 -140.93162 0.48764   1.000 32.70929  ? 289 TRP A N   1 
ATOM   2049 C  CA  . TRP A 1 290 ? -46.15214 -140.69935 1.32940   1.000 32.13890  ? 289 TRP A CA  1 
ATOM   2050 C  C   . TRP A 1 290 ? -47.42918 -140.54217 0.51400   1.000 32.00191  ? 289 TRP A C   1 
ATOM   2051 O  O   . TRP A 1 290 ? -48.52762 -140.77606 1.03335   1.000 33.34342  ? 289 TRP A O   1 
ATOM   2052 C  CB  . TRP A 1 290 ? -45.96255 -139.44901 2.19849   1.000 30.65830  ? 289 TRP A CB  1 
ATOM   2053 C  CG  . TRP A 1 290 ? -47.12065 -139.29918 3.15513   1.000 31.06171  ? 289 TRP A CG  1 
ATOM   2054 C  CD1 . TRP A 1 290 ? -47.36912 -140.07301 4.24640   1.000 29.88701  ? 289 TRP A CD1 1 
ATOM   2055 C  CD2 . TRP A 1 290 ? -48.20454 -138.36017 3.06824   1.000 29.62721  ? 289 TRP A CD2 1 
ATOM   2056 N  NE1 . TRP A 1 290 ? -48.53325 -139.66272 4.86423   1.000 30.60191  ? 289 TRP A NE1 1 
ATOM   2057 C  CE2 . TRP A 1 290 ? -49.06997 -138.62073 4.15870   1.000 28.20017  ? 289 TRP A CE2 1 
ATOM   2058 C  CE3 . TRP A 1 290 ? -48.52736 -137.32171 2.17548   1.000 29.95708  ? 289 TRP A CE3 1 
ATOM   2059 C  CZ2 . TRP A 1 290 ? -50.23580 -137.87400 4.39349   1.000 32.70280  ? 289 TRP A CZ2 1 
ATOM   2060 C  CZ3 . TRP A 1 290 ? -49.69149 -136.58333 2.39478   1.000 32.56748  ? 289 TRP A CZ3 1 
ATOM   2061 C  CH2 . TRP A 1 290 ? -50.53340 -136.86324 3.50485   1.000 30.59524  ? 289 TRP A CH2 1 
ATOM   2062 N  N   . MET A 1 291 ? -47.31506 -140.13407 -0.74659  1.000 28.78603  ? 290 MET A N   1 
ATOM   2063 C  CA  . MET A 1 291 ? -48.48514 -139.81057 -1.55460  1.000 31.48419  ? 290 MET A CA  1 
ATOM   2064 C  C   . MET A 1 291 ? -49.05088 -140.99558 -2.32400  1.000 35.09595  ? 290 MET A C   1 
ATOM   2065 O  O   . MET A 1 291 ? -50.05328 -140.83079 -3.02443  1.000 35.11771  ? 290 MET A O   1 
ATOM   2066 C  CB  . MET A 1 291 ? -48.14445 -138.69100 -2.54581  1.000 30.50107  ? 290 MET A CB  1 
ATOM   2067 C  CG  . MET A 1 291 ? -47.82902 -137.35031 -1.86391  1.000 34.63300  ? 290 MET A CG  1 
ATOM   2068 S  SD  . MET A 1 291 ? -49.13134 -136.13180 -2.16785  1.000 38.06087  ? 290 MET A SD  1 
ATOM   2069 C  CE  . MET A 1 291 ? -50.48918 -136.84470 -1.28618  1.000 30.40839  ? 290 MET A CE  1 
ATOM   2070 N  N   . GLN A 1 292 ? -48.44901 -142.17403 -2.22412  1.000 34.52380  ? 291 GLN A N   1 
ATOM   2071 C  CA  . GLN A 1 292 ? -48.88529 -143.27877 -3.06473  1.000 40.83901  ? 291 GLN A CA  1 
ATOM   2072 C  C   . GLN A 1 292 ? -50.18134 -143.90618 -2.53598  1.000 42.77455  ? 291 GLN A C   1 
ATOM   2073 O  O   . GLN A 1 292 ? -50.53723 -143.77391 -1.36050  1.000 35.41297  ? 291 GLN A O   1 
ATOM   2074 C  CB  . GLN A 1 292 ? -47.76582 -144.31837 -3.18184  1.000 38.12717  ? 291 GLN A CB  1 
ATOM   2075 C  CG  . GLN A 1 292 ? -46.51372 -143.75796 -3.91054  1.000 40.52192  ? 291 GLN A CG  1 
ATOM   2076 C  CD  . GLN A 1 292 ? -46.85780 -142.77890 -5.05842  1.000 51.42231  ? 291 GLN A CD  1 
ATOM   2077 O  OE1 . GLN A 1 292 ? -47.42713 -143.17578 -6.07851  1.000 45.22025  ? 291 GLN A OE1 1 
ATOM   2078 N  NE2 . GLN A 1 292 ? -46.51235 -141.49041 -4.88118  1.000 36.98282  ? 291 GLN A NE2 1 
ATOM   2079 N  N   . ASP A 1 293 ? -50.91342 -144.55804 -3.44763  1.000 37.44778  ? 292 ASP A N   1 
ATOM   2080 C  CA  . ASP A 1 293 ? -52.12194 -145.32130 -3.10603  1.000 43.20084  ? 292 ASP A CA  1 
ATOM   2081 C  C   . ASP A 1 293 ? -53.23146 -144.42556 -2.55200  1.000 41.22284  ? 292 ASP A C   1 
ATOM   2082 O  O   . ASP A 1 293 ? -53.90349 -144.76525 -1.57663  1.000 37.36289  ? 292 ASP A O   1 
ATOM   2083 C  CB  . ASP A 1 293 ? -51.79643 -146.45151 -2.12425  1.000 45.69802  ? 292 ASP A CB  1 
ATOM   2084 C  CG  . ASP A 1 293 ? -50.93233 -147.52654 -2.75696  1.000 55.78514  ? 292 ASP A CG  1 
ATOM   2085 O  OD1 . ASP A 1 293 ? -51.15437 -147.83157 -3.94885  1.000 62.45594  ? 292 ASP A OD1 1 
ATOM   2086 O  OD2 . ASP A 1 293 ? -50.02356 -148.04709 -2.07629  1.000 61.22229  ? 292 ASP A OD2 1 
ATOM   2087 N  N   . VAL A 1 294 ? -53.43862 -143.27575 -3.18965  1.000 31.84946  ? 293 VAL A N   1 
ATOM   2088 C  CA  . VAL A 1 294 ? -54.45415 -142.34064 -2.72331  1.000 34.08463  ? 293 VAL A CA  1 
ATOM   2089 C  C   . VAL A 1 294 ? -55.85069 -142.94688 -2.87582  1.000 36.31298  ? 293 VAL A C   1 
ATOM   2090 O  O   . VAL A 1 294 ? -56.12007 -143.74412 -3.78607  1.000 36.55356  ? 293 VAL A O   1 
ATOM   2091 C  CB  . VAL A 1 294 ? -54.32009 -141.01537 -3.49631  1.000 33.97350  ? 293 VAL A CB  1 
ATOM   2092 C  CG1 . VAL A 1 294 ? -54.65148 -141.23749 -4.97366  1.000 35.22611  ? 293 VAL A CG1 1 
ATOM   2093 C  CG2 . VAL A 1 294 ? -55.20408 -139.92633 -2.87884  1.000 33.23821  ? 293 VAL A CG2 1 
ATOM   2094 N  N   . LEU A 1 295 ? -56.75314 -142.56949 -1.97368  1.000 32.23058  ? 294 LEU A N   1 
ATOM   2095 C  CA  . LEU A 1 295 ? -58.15629 -142.93055 -2.12226  1.000 33.82568  ? 294 LEU A CA  1 
ATOM   2096 C  C   . LEU A 1 295 ? -58.80047 -142.11902 -3.23917  1.000 34.72983  ? 294 LEU A C   1 
ATOM   2097 O  O   . LEU A 1 295 ? -58.41043 -140.98488 -3.50794  1.000 35.19363  ? 294 LEU A O   1 
ATOM   2098 C  CB  . LEU A 1 295 ? -58.92983 -142.66618 -0.82761  1.000 33.69394  ? 294 LEU A CB  1 
ATOM   2099 C  CG  . LEU A 1 295 ? -58.61487 -143.49840 0.41331   1.000 36.52928  ? 294 LEU A CG  1 
ATOM   2100 C  CD1 . LEU A 1 295 ? -59.47483 -142.96838 1.56681   1.000 41.86815  ? 294 LEU A CD1 1 
ATOM   2101 C  CD2 . LEU A 1 295 ? -58.91704 -144.96236 0.16377   1.000 37.47044  ? 294 LEU A CD2 1 
ATOM   2102 N  N   . LEU A 1 296 ? -59.81561 -142.70250 -3.86501  1.000 35.68371  ? 295 LEU A N   1 
ATOM   2103 C  CA  . LEU A 1 296 ? -60.66639 -141.96264 -4.78806  1.000 41.10455  ? 295 LEU A CA  1 
ATOM   2104 C  C   . LEU A 1 296 ? -61.63353 -141.07193 -4.00701  1.000 39.11525  ? 295 LEU A C   1 
ATOM   2105 O  O   . LEU A 1 296 ? -61.89649 -141.31178 -2.82505  1.000 34.48581  ? 295 LEU A O   1 
ATOM   2106 C  CB  . LEU A 1 296 ? -61.44786 -142.92652 -5.67666  1.000 40.29006  ? 295 LEU A CB  1 
ATOM   2107 C  CG  . LEU A 1 296 ? -60.70344 -144.03568 -6.42717  1.000 43.63472  ? 295 LEU A CG  1 
ATOM   2108 C  CD1 . LEU A 1 296 ? -61.70804 -144.85892 -7.23249  1.000 43.71995  ? 295 LEU A CD1 1 
ATOM   2109 C  CD2 . LEU A 1 296 ? -59.61078 -143.47422 -7.33136  1.000 41.94760  ? 295 LEU A CD2 1 
ATOM   2110 N  N   . PRO A 1 297 ? -62.17888 -140.02882 -4.64173  1.000 38.46522  ? 296 PRO A N   1 
ATOM   2111 C  CA  . PRO A 1 297 ? -63.06640 -139.12172 -3.88810  1.000 35.61016  ? 296 PRO A CA  1 
ATOM   2112 C  C   . PRO A 1 297 ? -64.26420 -139.82069 -3.27142  1.000 40.89050  ? 296 PRO A C   1 
ATOM   2113 O  O   . PRO A 1 297 ? -64.59346 -139.56357 -2.10827  1.000 38.83116  ? 296 PRO A O   1 
ATOM   2114 C  CB  . PRO A 1 297 ? -63.48323 -138.08869 -4.94424  1.000 36.65756  ? 296 PRO A CB  1 
ATOM   2115 C  CG  . PRO A 1 297 ? -62.31224 -138.06325 -5.89576  1.000 41.38867  ? 296 PRO A CG  1 
ATOM   2116 C  CD  . PRO A 1 297 ? -61.88161 -139.50975 -5.99117  1.000 40.57310  ? 296 PRO A CD  1 
ATOM   2117 N  N   . GLN A 1 298 ? -64.91589 -140.72104 -4.01010  1.000 39.62641  ? 297 GLN A N   1 
ATOM   2118 C  CA  . GLN A 1 298 ? -66.07509 -141.40959 -3.45549  1.000 43.02870  ? 297 GLN A CA  1 
ATOM   2119 C  C   . GLN A 1 298 ? -65.67816 -142.31316 -2.29224  1.000 40.41301  ? 297 GLN A C   1 
ATOM   2120 O  O   . GLN A 1 298 ? -66.41037 -142.40941 -1.30242  1.000 43.45712  ? 297 GLN A O   1 
ATOM   2121 C  CB  . GLN A 1 298 ? -66.78266 -142.20979 -4.55103  1.000 44.15889  ? 297 GLN A CB  1 
ATOM   2122 N  N   . GLU A 1 299 ? -64.53450 -142.99771 -2.39864  1.000 41.85315  ? 298 GLU A N   1 
ATOM   2123 C  CA  . GLU A 1 299 ? -64.04018 -143.79071 -1.27284  1.000 42.50329  ? 298 GLU A CA  1 
ATOM   2124 C  C   . GLU A 1 299 ? -63.78918 -142.90061 -0.05438  1.000 39.58812  ? 298 GLU A C   1 
ATOM   2125 O  O   . GLU A 1 299 ? -64.12675 -143.26350 1.08030   1.000 42.14964  ? 298 GLU A O   1 
ATOM   2126 C  CB  . GLU A 1 299 ? -62.74559 -144.52264 -1.66211  1.000 42.55281  ? 298 GLU A CB  1 
ATOM   2127 C  CG  . GLU A 1 299 ? -62.86658 -145.65983 -2.68943  1.000 44.82589  ? 298 GLU A CG  1 
ATOM   2128 C  CD  . GLU A 1 299 ? -61.49305 -146.14716 -3.19568  1.000 47.11962  ? 298 GLU A CD  1 
ATOM   2129 O  OE1 . GLU A 1 299 ? -60.48058 -145.45071 -2.96721  1.000 39.70495  ? 298 GLU A OE1 1 
ATOM   2130 O  OE2 . GLU A 1 299 ? -61.42066 -147.22450 -3.82481  1.000 49.76025  ? 298 GLU A OE2 1 
ATOM   2131 N  N   . THR A 1 300 ? -63.19565 -141.72912 -0.28220  1.000 35.35726  ? 299 THR A N   1 
ATOM   2132 C  CA  . THR A 1 300 ? -62.93341 -140.77766 0.79355   1.000 36.77826  ? 299 THR A CA  1 
ATOM   2133 C  C   . THR A 1 300 ? -64.22254 -140.37755 1.50173   1.000 39.63040  ? 299 THR A C   1 
ATOM   2134 O  O   . THR A 1 300 ? -64.27212 -140.31882 2.73448   1.000 39.28962  ? 299 THR A O   1 
ATOM   2135 C  CB  . THR A 1 300 ? -62.22883 -139.54935 0.21686   1.000 39.85675  ? 299 THR A CB  1 
ATOM   2136 O  OG1 . THR A 1 300 ? -61.04286 -139.95989 -0.47897  1.000 37.24128  ? 299 THR A OG1 1 
ATOM   2137 C  CG2 . THR A 1 300 ? -61.84875 -138.57377 1.30326   1.000 38.60451  ? 299 THR A CG2 1 
ATOM   2138 N  N   . ALA A 1 301 ? -65.27904 -140.10632 0.73482   1.000 43.18677  ? 300 ALA A N   1 
ATOM   2139 C  CA  . ALA A 1 301 ? -66.54585 -139.70724 1.33359   1.000 44.88542  ? 300 ALA A CA  1 
ATOM   2140 C  C   . ALA A 1 301 ? -67.13371 -140.84086 2.16144   1.000 45.10253  ? 300 ALA A C   1 
ATOM   2141 O  O   . ALA A 1 301 ? -67.56950 -140.63061 3.29813   1.000 42.65585  ? 300 ALA A O   1 
ATOM   2142 C  CB  . ALA A 1 301 ? -67.52631 -139.26619 0.24408   1.000 38.80925  ? 300 ALA A CB  1 
ATOM   2143 N  N   . GLU A 1 302 ? -67.13560 -142.05577 1.60796   1.000 39.79005  ? 301 GLU A N   1 
ATOM   2144 C  CA  . GLU A 1 302 ? -67.75813 -143.18459 2.28873   1.000 45.86337  ? 301 GLU A CA  1 
ATOM   2145 C  C   . GLU A 1 302 ? -66.98365 -143.58029 3.53994   1.000 50.07713  ? 301 GLU A C   1 
ATOM   2146 O  O   . GLU A 1 302 ? -67.58222 -143.96429 4.55220   1.000 47.83153  ? 301 GLU A O   1 
ATOM   2147 C  CB  . GLU A 1 302 ? -67.87293 -144.36373 1.32579   1.000 51.65717  ? 301 GLU A CB  1 
ATOM   2148 C  CG  . GLU A 1 302 ? -68.75062 -144.06971 0.12947   1.000 56.02595  ? 301 GLU A CG  1 
ATOM   2149 C  CD  . GLU A 1 302 ? -68.71171 -145.17053 -0.91255  1.000 71.68163  ? 301 GLU A CD  1 
ATOM   2150 O  OE1 . GLU A 1 302 ? -67.85118 -146.07319 -0.79475  1.000 71.82846  ? 301 GLU A OE1 1 
ATOM   2151 O  OE2 . GLU A 1 302 ? -69.54170 -145.12623 -1.84889  1.000 66.82317  ? 301 GLU A OE2 1 
ATOM   2152 N  N   . ILE A 1 303 ? -65.65582 -143.48668 3.50067   1.000 41.44800  ? 302 ILE A N   1 
ATOM   2153 C  CA  . ILE A 1 303 ? -64.87304 -143.89684 4.66260   1.000 40.98124  ? 302 ILE A CA  1 
ATOM   2154 C  C   . ILE A 1 303 ? -64.85836 -142.80506 5.73239   1.000 46.86614  ? 302 ILE A C   1 
ATOM   2155 O  O   . ILE A 1 303 ? -65.02491 -143.09195 6.92311   1.000 40.97412  ? 302 ILE A O   1 
ATOM   2156 C  CB  . ILE A 1 303 ? -63.44677 -144.29212 4.23746   1.000 39.93204  ? 302 ILE A CB  1 
ATOM   2157 C  CG1 . ILE A 1 303 ? -63.47098 -145.53305 3.33729   1.000 46.97631  ? 302 ILE A CG1 1 
ATOM   2158 C  CG2 . ILE A 1 303 ? -62.58269 -144.54614 5.46702   1.000 41.44475  ? 302 ILE A CG2 1 
ATOM   2159 C  CD1 . ILE A 1 303 ? -62.11112 -145.85932 2.72717   1.000 44.68461  ? 302 ILE A CD1 1 
ATOM   2160 N  N   . HIS A 1 304 ? -64.67961 -141.53754 5.33784   1.000 38.48500  ? 303 HIS A N   1 
ATOM   2161 C  CA  . HIS A 1 304 ? -64.33558 -140.48680 6.28905   1.000 44.51675  ? 303 HIS A CA  1 
ATOM   2162 C  C   . HIS A 1 304 ? -65.38085 -139.39696 6.47298   1.000 46.61126  ? 303 HIS A C   1 
ATOM   2163 O  O   . HIS A 1 304 ? -65.30615 -138.67210 7.47223   1.000 46.49586  ? 303 HIS A O   1 
ATOM   2164 C  CB  . HIS A 1 304 ? -63.02051 -139.79741 5.88043   1.000 40.28739  ? 303 HIS A CB  1 
ATOM   2165 C  CG  . HIS A 1 304 ? -61.82744 -140.70241 5.90565   1.000 39.02749  ? 303 HIS A CG  1 
ATOM   2166 N  ND1 . HIS A 1 304 ? -61.21225 -141.08993 7.07670   1.000 42.09002  ? 303 HIS A ND1 1 
ATOM   2167 C  CD2 . HIS A 1 304 ? -61.12154 -141.27721 4.90125   1.000 37.95863  ? 303 HIS A CD2 1 
ATOM   2168 C  CE1 . HIS A 1 304 ? -60.18623 -141.87338 6.79376   1.000 37.80778  ? 303 HIS A CE1 1 
ATOM   2169 N  NE2 . HIS A 1 304 ? -60.11201 -142.00568 5.48139   1.000 41.09567  ? 303 HIS A NE2 1 
ATOM   2170 N  N   . LEU A 1 305 ? -66.32701 -139.23552 5.54924   1.000 42.66412  ? 304 LEU A N   1 
ATOM   2171 C  CA  . LEU A 1 305 ? -67.18792 -138.05954 5.54892   1.000 44.89732  ? 304 LEU A CA  1 
ATOM   2172 C  C   . LEU A 1 305 ? -68.65733 -138.36214 5.81493   1.000 54.76428  ? 304 LEU A C   1 
ATOM   2173 O  O   . LEU A 1 305 ? -69.34167 -137.53046 6.41213   1.000 55.31572  ? 304 LEU A O   1 
ATOM   2174 C  CB  . LEU A 1 305 ? -67.06844 -137.31137 4.21504   1.000 42.78961  ? 304 LEU A CB  1 
ATOM   2175 C  CG  . LEU A 1 305 ? -65.65737 -136.92548 3.74503   1.000 40.03770  ? 304 LEU A CG  1 
ATOM   2176 C  CD1 . LEU A 1 305 ? -65.71488 -136.10949 2.46268   1.000 40.46103  ? 304 LEU A CD1 1 
ATOM   2177 C  CD2 . LEU A 1 305 ? -64.91108 -136.15512 4.81759   1.000 42.90560  ? 304 LEU A CD2 1 
ATOM   2178 N  N   . HIS A 1 306 ? -69.16071 -139.51448 5.38822   1.000 48.85042  ? 305 HIS A N   1 
ATOM   2179 C  CA  . HIS A 1 306 ? -70.54461 -139.88880 5.66752   1.000 64.13468  ? 305 HIS A CA  1 
ATOM   2180 C  C   . HIS A 1 306 ? -70.68953 -140.37507 7.10795   1.000 57.55343  ? 305 HIS A C   1 
ATOM   2181 O  O   . HIS A 1 306 ? -71.57361 -139.92626 7.83743   1.000 73.51912  ? 305 HIS A O   1 
ATOM   2182 C  CB  . HIS A 1 306 ? -71.02462 -140.97299 4.69796   1.000 59.22946  ? 305 HIS A CB  1 
ATOM   2183 C  CG  . HIS A 1 306 ? -71.01226 -140.55187 3.26063   1.000 57.11598  ? 305 HIS A CG  1 
ATOM   2184 N  ND1 . HIS A 1 306 ? -71.23847 -141.43407 2.22578   1.000 54.86169  ? 305 HIS A ND1 1 
ATOM   2185 C  CD2 . HIS A 1 306 ? -70.80082 -139.34382 2.68425   1.000 59.70119  ? 305 HIS A CD2 1 
ATOM   2186 C  CE1 . HIS A 1 306 ? -71.16193 -140.79001 1.07483   1.000 55.02578  ? 305 HIS A CE1 1 
ATOM   2187 N  NE2 . HIS A 1 306 ? -70.90014 -139.52023 1.32442   1.000 54.42109  ? 305 HIS A NE2 1 
ATOM   2188 N  N   . ARG B 2 2   ? -54.80773 -125.09551 22.86693  1.000 61.53867  ? 2   ARG B N   1 
ATOM   2189 C  CA  . ARG B 2 2   ? -54.09176 -124.08302 22.09441  1.000 59.00983  ? 2   ARG B CA  1 
ATOM   2190 C  C   . ARG B 2 2   ? -55.01544 -123.42443 21.07383  1.000 63.34054  ? 2   ARG B C   1 
ATOM   2191 O  O   . ARG B 2 2   ? -55.63161 -124.11368 20.24887  1.000 62.33574  ? 2   ARG B O   1 
ATOM   2192 C  CB  . ARG B 2 2   ? -52.87519 -124.69650 21.38323  1.000 53.19176  ? 2   ARG B CB  1 
ATOM   2193 C  CG  . ARG B 2 2   ? -52.02528 -123.68852 20.60839  1.000 54.09962  ? 2   ARG B CG  1 
ATOM   2194 C  CD  . ARG B 2 2   ? -50.77297 -124.33717 19.99903  1.000 48.38444  ? 2   ARG B CD  1 
ATOM   2195 N  NE  . ARG B 2 2   ? -49.97384 -125.02576 21.00702  1.000 47.75895  ? 2   ARG B NE  1 
ATOM   2196 C  CZ  . ARG B 2 2   ? -49.91100 -126.34447 21.14145  1.000 51.86481  ? 2   ARG B CZ  1 
ATOM   2197 N  NH1 . ARG B 2 2   ? -50.52888 -127.15560 20.29277  1.000 42.70967  ? 2   ARG B NH1 1 
ATOM   2198 N  NH2 . ARG B 2 2   ? -49.21449 -126.86320 22.15370  1.000 44.08609  ? 2   ARG B NH2 1 
ATOM   2199 N  N   . LYS B 2 3   ? -55.08581 -122.09092 21.12211  1.000 57.32277  ? 3   LYS B N   1 
ATOM   2200 C  CA  . LYS B 2 3   ? -55.93769 -121.33994 20.20477  1.000 50.65655  ? 3   LYS B CA  1 
ATOM   2201 C  C   . LYS B 2 3   ? -55.54194 -121.58291 18.75375  1.000 51.70802  ? 3   LYS B C   1 
ATOM   2202 O  O   . LYS B 2 3   ? -54.35905 -121.65827 18.41102  1.000 54.41130  ? 3   LYS B O   1 
ATOM   2203 C  CB  . LYS B 2 3   ? -55.86466 -119.84314 20.50344  1.000 47.03383  ? 3   LYS B CB  1 
ATOM   2204 N  N   . ARG B 2 4   ? -56.55066 -121.69923 17.90515  1.000 48.07599  ? 4   ARG B N   1 
ATOM   2205 C  CA  . ARG B 2 4   ? -56.39722 -121.80781 16.46161  1.000 42.56006  ? 4   ARG B CA  1 
ATOM   2206 C  C   . ARG B 2 4   ? -57.28165 -120.74075 15.84766  1.000 46.10268  ? 4   ARG B C   1 
ATOM   2207 O  O   . ARG B 2 4   ? -58.41772 -120.54540 16.29136  1.000 46.01330  ? 4   ARG B O   1 
ATOM   2208 C  CB  . ARG B 2 4   ? -56.79365 -123.19379 15.98101  1.000 45.38046  ? 4   ARG B CB  1 
ATOM   2209 C  CG  . ARG B 2 4   ? -57.26525 -123.30202 14.53545  1.000 39.06764  ? 4   ARG B CG  1 
ATOM   2210 C  CD  . ARG B 2 4   ? -57.59030 -124.76179 14.22668  1.000 38.48284  ? 4   ARG B CD  1 
ATOM   2211 N  NE  . ARG B 2 4   ? -58.20748 -124.92939 12.90977  1.000 37.63339  ? 4   ARG B NE  1 
ATOM   2212 C  CZ  . ARG B 2 4   ? -57.52933 -125.04760 11.77404  1.000 37.12189  ? 4   ARG B CZ  1 
ATOM   2213 N  NH1 . ARG B 2 4   ? -56.21102 -124.93732 11.74152  1.000 37.41123  ? 4   ARG B NH1 1 
ATOM   2214 N  NH2 . ARG B 2 4   ? -58.19144 -125.28180 10.64098  1.000 36.32503  ? 4   ARG B NH2 1 
ATOM   2215 N  N   . ARG B 2 5   ? -56.76219 -120.01841 14.86296  1.000 40.14422  ? 5   ARG B N   1 
ATOM   2216 C  CA  . ARG B 2 5   ? -57.53021 -118.90958 14.32746  1.000 46.79807  ? 5   ARG B CA  1 
ATOM   2217 C  C   . ARG B 2 5   ? -57.34678 -118.80365 12.82300  1.000 40.29603  ? 5   ARG B C   1 
ATOM   2218 O  O   . ARG B 2 5   ? -56.38849 -119.32646 12.24410  1.000 39.00567  ? 5   ARG B O   1 
ATOM   2219 C  CB  . ARG B 2 5   ? -57.14427 -117.58865 15.00646  1.000 46.19370  ? 5   ARG B CB  1 
ATOM   2220 C  CG  . ARG B 2 5   ? -55.71257 -117.14224 14.75401  1.000 50.98790  ? 5   ARG B CG  1 
ATOM   2221 C  CD  . ARG B 2 5   ? -55.45870 -115.83045 15.48605  1.000 61.19500  ? 5   ARG B CD  1 
ATOM   2222 N  NE  . ARG B 2 5   ? -54.23125 -115.16610 15.06668  1.000 67.12167  ? 5   ARG B NE  1 
ATOM   2223 C  CZ  . ARG B 2 5   ? -54.14422 -114.30812 14.05669  1.000 69.76863  ? 5   ARG B CZ  1 
ATOM   2224 N  NH1 . ARG B 2 5   ? -55.18811 -114.03425 13.28182  1.000 55.91579  ? 5   ARG B NH1 1 
ATOM   2225 N  NH2 . ARG B 2 5   ? -52.97868 -113.71232 13.81355  1.000 69.15520  ? 5   ARG B NH2 1 
ATOM   2226 N  N   . ARG B 2 6   ? -58.30852 -118.13162 12.19525  1.000 38.86041  ? 6   ARG B N   1 
ATOM   2227 C  CA  . ARG B 2 6   ? -58.18416 -117.75194 10.80178  1.000 39.88489  ? 6   ARG B CA  1 
ATOM   2228 C  C   . ARG B 2 6   ? -57.22379 -116.57239 10.68642  1.000 42.32699  ? 6   ARG B C   1 
ATOM   2229 O  O   . ARG B 2 6   ? -56.92400 -115.89015 11.67063  1.000 40.09725  ? 6   ARG B O   1 
ATOM   2230 C  CB  . ARG B 2 6   ? -59.55461 -117.38818 10.22141  1.000 39.24137  ? 6   ARG B CB  1 
ATOM   2231 C  CG  . ARG B 2 6   ? -60.58696 -118.51825 10.27864  1.000 39.04186  ? 6   ARG B CG  1 
ATOM   2232 C  CD  . ARG B 2 6   ? -61.97913 -118.02046 9.89430   1.000 41.00843  ? 6   ARG B CD  1 
ATOM   2233 N  NE  . ARG B 2 6   ? -62.91243 -119.11333 9.63901   1.000 44.30893  ? 6   ARG B NE  1 
ATOM   2234 C  CZ  . ARG B 2 6   ? -63.08382 -119.69417 8.45650   1.000 44.07458  ? 6   ARG B CZ  1 
ATOM   2235 N  NH1 . ARG B 2 6   ? -62.39277 -119.31719 7.39596   1.000 41.18286  ? 6   ARG B NH1 1 
ATOM   2236 N  NH2 . ARG B 2 6   ? -63.95523 -120.69267 8.34217   1.000 38.70181  ? 6   ARG B NH2 1 
ATOM   2237 N  N   . HIS B 2 7   ? -56.73313 -116.34152 9.46702   1.000 40.18724  ? 7   HIS B N   1 
ATOM   2238 C  CA  . HIS B 2 7   ? -55.81427 -115.24565 9.19430   1.000 44.83106  ? 7   HIS B CA  1 
ATOM   2239 C  C   . HIS B 2 7   ? -56.29478 -114.49414 7.95871   1.000 43.30955  ? 7   HIS B C   1 
ATOM   2240 O  O   . HIS B 2 7   ? -56.55083 -115.11490 6.92283   1.000 42.68769  ? 7   HIS B O   1 
ATOM   2241 C  CB  . HIS B 2 7   ? -54.38659 -115.75220 8.97804   1.000 40.26686  ? 7   HIS B CB  1 
ATOM   2242 C  CG  . HIS B 2 7   ? -53.84970 -116.53452 10.13021  1.000 39.13454  ? 7   HIS B CG  1 
ATOM   2243 N  ND1 . HIS B 2 7   ? -54.12580 -117.87131 10.31027  1.000 38.83633  ? 7   HIS B ND1 1 
ATOM   2244 C  CD2 . HIS B 2 7   ? -53.06645 -116.16644 11.17057  1.000 42.75350  ? 7   HIS B CD2 1 
ATOM   2245 C  CE1 . HIS B 2 7   ? -53.53184 -118.29494 11.41161  1.000 41.40859  ? 7   HIS B CE1 1 
ATOM   2246 N  NE2 . HIS B 2 7   ? -52.88547 -117.27795 11.95468  1.000 41.33614  ? 7   HIS B NE2 1 
ATOM   2247 N  N   . PRO B 2 8   ? -56.40759 -113.17414 8.01481   1.000 52.13883  ? 8   PRO B N   1 
ATOM   2248 C  CA  . PRO B 2 8   ? -56.92636 -112.43613 6.85916   1.000 51.21734  ? 8   PRO B CA  1 
ATOM   2249 C  C   . PRO B 2 8   ? -55.91825 -112.37621 5.72330   1.000 51.77470  ? 8   PRO B C   1 
ATOM   2250 O  O   . PRO B 2 8   ? -54.70613 -112.50317 5.91138   1.000 56.66269  ? 8   PRO B O   1 
ATOM   2251 C  CB  . PRO B 2 8   ? -57.21175 -111.04068 7.42657   1.000 59.69133  ? 8   PRO B CB  1 
ATOM   2252 C  CG  . PRO B 2 8   ? -56.23014 -110.89756 8.54760   1.000 67.68362  ? 8   PRO B CG  1 
ATOM   2253 C  CD  . PRO B 2 8   ? -56.06765 -112.28539 9.14126   1.000 55.62910  ? 8   PRO B CD  1 
ATOM   2254 N  N   . SER B 2 9   ? -56.45118 -112.19618 4.52018   1.000 58.71734  ? 9   SER B N   1 
ATOM   2255 C  CA  . SER B 2 9   ? -55.64481 -111.95516 3.33070   1.000 60.18228  ? 9   SER B CA  1 
ATOM   2256 C  C   . SER B 2 9   ? -55.35260 -110.46372 3.16270   1.000 69.68317  ? 9   SER B C   1 
ATOM   2257 O  O   . SER B 2 9   ? -54.22352 -110.06910 2.85329   1.000 68.82243  ? 9   SER B O   1 
ATOM   2258 C  CB  . SER B 2 9   ? -56.35685 -112.49612 2.09525   1.000 55.44359  ? 9   SER B CB  1 
ATOM   2259 O  OG  . SER B 2 9   ? -56.50277 -113.90613 2.17784   1.000 56.90756  ? 9   SER B OG  1 
HETATM 2260 C  C1  . EDO C 3 .   ? -65.30456 -117.44884 -4.15395  1.000 49.61574  ? 401 EDO A C1  1 
HETATM 2261 O  O1  . EDO C 3 .   ? -64.42477 -116.33294 -3.98121  1.000 45.91613  ? 401 EDO A O1  1 
HETATM 2262 C  C2  . EDO C 3 .   ? -65.16065 -118.14803 -5.50107  1.000 37.84734  ? 401 EDO A C2  1 
HETATM 2263 O  O2  . EDO C 3 .   ? -63.79797 -118.34959 -5.85426  1.000 35.92000  ? 401 EDO A O2  1 
HETATM 2264 C  C1  . GOL D 4 .   ? -58.39313 -111.47016 -0.83439  0.824 52.40173  ? 402 GOL A C1  1 
HETATM 2265 O  O1  . GOL D 4 .   ? -58.10663 -112.55921 -1.64158  0.824 45.83005  ? 402 GOL A O1  1 
HETATM 2266 C  C2  . GOL D 4 .   ? -59.78395 -110.93565 -1.23438  0.824 48.62234  ? 402 GOL A C2  1 
HETATM 2267 O  O2  . GOL D 4 .   ? -60.50342 -111.77638 -2.13181  0.824 47.28591  ? 402 GOL A O2  1 
HETATM 2268 C  C3  . GOL D 4 .   ? -60.50701 -110.75822 0.09548   0.824 57.02946  ? 402 GOL A C3  1 
HETATM 2269 O  O3  . GOL D 4 .   ? -61.15224 -109.54945 0.00304   0.824 43.54648  ? 402 GOL A O3  1 
HETATM 2270 C  C1  . GOL E 4 .   ? -44.16716 -125.02126 16.00937  0.851 53.49769  ? 403 GOL A C1  1 
HETATM 2271 O  O1  . GOL E 4 .   ? -44.77086 -126.04121 15.25438  0.851 42.62036  ? 403 GOL A O1  1 
HETATM 2272 C  C2  . GOL E 4 .   ? -42.75994 -124.75066 15.38692  0.851 50.64135  ? 403 GOL A C2  1 
HETATM 2273 O  O2  . GOL E 4 .   ? -42.61935 -125.33835 14.14120  0.851 42.62744  ? 403 GOL A O2  1 
HETATM 2274 C  C3  . GOL E 4 .   ? -42.62929 -123.20739 15.33797  0.851 49.20099  ? 403 GOL A C3  1 
HETATM 2275 O  O3  . GOL E 4 .   ? -41.40046 -122.93843 14.74260  0.851 51.34788  ? 403 GOL A O3  1 
HETATM 2276 C  C1  . GOL F 4 .   ? -54.53395 -139.09736 13.65350  0.726 50.38155  ? 404 GOL A C1  1 
HETATM 2277 O  O1  . GOL F 4 .   ? -55.53652 -138.13011 13.54005  0.726 46.64821  ? 404 GOL A O1  1 
HETATM 2278 C  C2  . GOL F 4 .   ? -53.21966 -138.32257 13.51036  0.726 42.60650  ? 404 GOL A C2  1 
HETATM 2279 O  O2  . GOL F 4 .   ? -52.20165 -138.81241 14.33192  0.726 52.27703  ? 404 GOL A O2  1 
HETATM 2280 C  C3  . GOL F 4 .   ? -52.87572 -138.46650 12.01684  0.726 46.60265  ? 404 GOL A C3  1 
HETATM 2281 O  O3  . GOL F 4 .   ? -52.63429 -137.18080 11.56561  0.726 38.07838  ? 404 GOL A O3  1 
HETATM 2282 C  C10 . XGF G 5 .   ? -70.00863 -122.18359 -2.18152  1.000 35.35994  ? 405 XGF A C10 1 
HETATM 2283 C  C2  . XGF G 5 .   ? -71.14919 -123.31529 -0.74122  1.000 39.89521  ? 405 XGF A C2  1 
HETATM 2284 C  C4  . XGF G 5 .   ? -69.74486 -121.71993 -0.91027  1.000 40.81940  ? 405 XGF A C4  1 
HETATM 2285 C  C5  . XGF G 5 .   ? -68.87437 -120.65059 -0.73241  1.000 38.83101  ? 405 XGF A C5  1 
HETATM 2286 C  C6  . XGF G 5 .   ? -68.30994 -120.09969 -1.87198  1.000 39.29560  ? 405 XGF A C6  1 
HETATM 2287 C  C8  . XGF G 5 .   ? -68.57832 -120.57070 -3.14939  1.000 36.72484  ? 405 XGF A C8  1 
HETATM 2288 C  C9  . XGF G 5 .   ? -69.44607 -121.63659 -3.31670  1.000 33.65837  ? 405 XGF A C9  1 
HETATM 2289 N  N1  . XGF G 5 .   ? -72.00427 -124.25736 -0.36106  1.000 46.68312  ? 405 XGF A N1  1 
HETATM 2290 N  N3  . XGF G 5 .   ? -70.48939 -122.46233 0.00642   1.000 32.41249  ? 405 XGF A N3  1 
HETATM 2291 O  O11 . XGF G 5 .   ? -70.91393 -123.21334 -2.08318  1.000 42.75336  ? 405 XGF A O11 1 
HETATM 2292 BR BR7 . XGF G 5 .   ? -67.12958 -118.63131 -1.67532  0.745 43.43292  ? 405 XGF A BR7 1 
HETATM 2293 O  O   . HOH H 6 .   ? -66.56709 -98.72030  0.08072   1.000 66.12839  ? 501 HOH A O   1 
HETATM 2294 O  O   . HOH H 6 .   ? -57.75364 -114.87848 -1.36534  1.000 48.12502  ? 502 HOH A O   1 
HETATM 2295 O  O   . HOH H 6 .   ? -50.00913 -147.99702 -6.06166  1.000 65.89313  ? 503 HOH A O   1 
HETATM 2296 O  O   . HOH H 6 .   ? -67.02520 -110.15197 -2.00384  1.000 42.71387  ? 504 HOH A O   1 
HETATM 2297 O  O   . HOH H 6 .   ? -57.97215 -135.59961 15.24601  1.000 49.51355  ? 505 HOH A O   1 
HETATM 2298 O  O   . HOH H 6 .   ? -42.97338 -138.69036 -12.93196 1.000 44.04199  ? 506 HOH A O   1 
HETATM 2299 O  O   . HOH H 6 .   ? -55.50590 -145.99683 2.30050   1.000 47.23895  ? 507 HOH A O   1 
HETATM 2300 O  O   . HOH H 6 .   ? -45.64114 -141.98028 -8.64990  1.000 42.89849  ? 508 HOH A O   1 
HETATM 2301 O  O   . HOH H 6 .   ? -42.45137 -144.07136 14.28784  1.000 37.80390  ? 509 HOH A O   1 
HETATM 2302 O  O   . HOH H 6 .   ? -67.56853 -106.98717 0.33511   1.000 45.11441  ? 510 HOH A O   1 
HETATM 2303 O  O   . HOH H 6 .   ? -34.16831 -130.07388 -0.41608  1.000 49.92014  ? 511 HOH A O   1 
HETATM 2304 O  O   . HOH H 6 .   ? -59.92683 -115.81668 1.45182   1.000 52.32565  ? 512 HOH A O   1 
HETATM 2305 O  O   . HOH H 6 .   ? -67.68263 -131.78803 -8.87166  1.000 55.58012  ? 513 HOH A O   1 
HETATM 2306 O  O   . HOH H 6 .   ? -67.69383 -109.93328 4.70137   1.000 49.79381  ? 514 HOH A O   1 
HETATM 2307 O  O   . HOH H 6 .   ? -38.68517 -124.48232 7.15256   1.000 45.08000  ? 515 HOH A O   1 
HETATM 2308 O  O   . HOH H 6 .   ? -51.32986 -111.63063 -3.66253  1.000 50.68010  ? 516 HOH A O   1 
HETATM 2309 O  O   . HOH H 6 .   ? -54.89547 -145.17888 -5.54665  1.000 46.26801  ? 517 HOH A O   1 
HETATM 2310 O  O   . HOH H 6 .   ? -39.70952 -118.53460 -4.59508  1.000 34.52473  ? 518 HOH A O   1 
HETATM 2311 O  O   . HOH H 6 .   ? -69.50683 -114.65486 3.04402   1.000 45.72260  ? 519 HOH A O   1 
HETATM 2312 O  O   . HOH H 6 .   ? -51.71950 -136.90727 -11.67097 1.000 28.46642  ? 520 HOH A O   1 
HETATM 2313 O  O   . HOH H 6 .   ? -61.45719 -139.61350 9.67652   1.000 46.24805  ? 521 HOH A O   1 
HETATM 2314 O  O   . HOH H 6 .   ? -33.13950 -124.96048 2.00645   1.000 36.28645  ? 522 HOH A O   1 
HETATM 2315 O  O   . HOH H 6 .   ? -63.01527 -125.87395 -14.00286 1.000 42.04704  ? 523 HOH A O   1 
HETATM 2316 O  O   . HOH H 6 .   ? -47.70593 -121.28567 9.34475   1.000 31.31730  ? 524 HOH A O   1 
HETATM 2317 O  O   . HOH H 6 .   ? -63.20781 -115.43958 6.70301   1.000 57.77966  ? 525 HOH A O   1 
HETATM 2318 O  O   . HOH H 6 .   ? -55.13767 -121.89692 8.44942   1.000 33.33295  ? 526 HOH A O   1 
HETATM 2319 O  O   . HOH H 6 .   ? -66.45758 -118.62805 -16.50258 1.000 43.39833  ? 527 HOH A O   1 
HETATM 2320 O  O   . HOH H 6 .   ? -58.73133 -130.35092 -10.12712 1.000 36.32149  ? 528 HOH A O   1 
HETATM 2321 O  O   . HOH H 6 .   ? -73.91717 -125.44513 -8.52195  1.000 41.91566  ? 529 HOH A O   1 
HETATM 2322 O  O   . HOH H 6 .   ? -46.72236 -144.33813 10.38095  1.000 55.94439  ? 530 HOH A O   1 
HETATM 2323 O  O   . HOH H 6 .   ? -66.03356 -127.62659 -9.79956  1.000 41.53519  ? 531 HOH A O   1 
HETATM 2324 O  O   . HOH H 6 .   ? -44.28535 -107.25702 4.17309   1.000 57.42990  ? 532 HOH A O   1 
HETATM 2325 O  O   . HOH H 6 .   ? -36.59759 -136.32041 -6.79282  1.000 54.25490  ? 533 HOH A O   1 
HETATM 2326 O  O   . HOH H 6 .   ? -62.46665 -116.21236 -6.74216  1.000 32.11834  ? 534 HOH A O   1 
HETATM 2327 O  O   . HOH H 6 .   ? -42.52955 -117.08278 -11.18805 1.000 32.83112  ? 535 HOH A O   1 
HETATM 2328 O  O   . HOH H 6 .   ? -63.39113 -120.07635 4.73981   1.000 44.18750  ? 536 HOH A O   1 
HETATM 2329 O  O   . HOH H 6 .   ? -63.14554 -120.56513 -7.22949  1.000 36.74216  ? 537 HOH A O   1 
HETATM 2330 O  O   . HOH H 6 .   ? -73.45776 -105.64563 -6.31804  1.000 43.26280  ? 538 HOH A O   1 
HETATM 2331 O  O   . HOH H 6 .   ? -76.98577 -111.20015 -4.59117  1.000 49.02104  ? 539 HOH A O   1 
HETATM 2332 O  O   . HOH H 6 .   ? -30.07623 -122.16202 -4.19765  1.000 52.72817  ? 540 HOH A O   1 
HETATM 2333 O  O   . HOH H 6 .   ? -57.61875 -128.52890 14.85667  1.000 40.25567  ? 541 HOH A O   1 
HETATM 2334 O  O   . HOH H 6 .   ? -59.66019 -115.05244 7.28583   1.000 44.21855  ? 542 HOH A O   1 
HETATM 2335 O  O   . HOH H 6 .   ? -53.16255 -129.05577 16.91067  1.000 51.33344  ? 543 HOH A O   1 
HETATM 2336 O  O   . HOH H 6 .   ? -38.14140 -125.64735 -6.24337  1.000 36.93834  ? 544 HOH A O   1 
HETATM 2337 O  O   . HOH H 6 .   ? -46.60546 -119.23998 -0.06936  1.000 39.17980  ? 545 HOH A O   1 
HETATM 2338 O  O   . HOH H 6 .   ? -37.48330 -117.03392 -5.62672  1.000 40.23940  ? 546 HOH A O   1 
HETATM 2339 O  O   . HOH H 6 .   ? -82.01653 -118.11367 -15.07171 1.000 62.44826  ? 547 HOH A O   1 
HETATM 2340 O  O   . HOH H 6 .   ? -53.66258 -124.58931 17.53822  1.000 44.02190  ? 548 HOH A O   1 
HETATM 2341 O  O   . HOH H 6 .   ? -58.79188 -147.85893 3.42362   1.000 53.83046  ? 549 HOH A O   1 
HETATM 2342 O  O   . HOH H 6 .   ? -39.57103 -106.46849 -3.81641  1.000 53.46795  ? 550 HOH A O   1 
HETATM 2343 O  O   . HOH H 6 .   ? -50.24833 -122.20182 14.75545  1.000 43.19137  ? 551 HOH A O   1 
HETATM 2344 O  O   . HOH H 6 .   ? -40.82284 -125.98425 -5.94353  1.000 33.81478  ? 552 HOH A O   1 
HETATM 2345 O  O   . HOH H 6 .   ? -56.34269 -120.15147 -19.91791 1.000 54.53048  ? 553 HOH A O   1 
HETATM 2346 O  O   . HOH H 6 .   ? -58.99416 -114.99347 3.93657   1.000 57.43199  ? 554 HOH A O   1 
HETATM 2347 O  O   . HOH H 6 .   ? -49.88844 -140.52789 12.00680  1.000 48.35831  ? 555 HOH A O   1 
HETATM 2348 O  O   . HOH H 6 .   ? -44.77560 -109.05873 -9.44810  1.000 48.61416  ? 556 HOH A O   1 
HETATM 2349 O  O   . HOH H 6 .   ? -62.70544 -110.81681 -3.83789  1.000 47.90053  ? 557 HOH A O   1 
HETATM 2350 O  O   . HOH H 6 .   ? -45.23091 -119.50466 6.08931   1.000 31.64165  ? 558 HOH A O   1 
HETATM 2351 O  O   . HOH H 6 .   ? -39.52030 -132.89000 -11.22206 1.000 45.95812  ? 559 HOH A O   1 
HETATM 2352 O  O   . HOH H 6 .   ? -63.66340 -123.29778 12.95037  1.000 45.81438  ? 560 HOH A O   1 
HETATM 2353 O  O   . HOH H 6 .   ? -61.13322 -131.97590 -6.32182  1.000 35.08532  ? 561 HOH A O   1 
HETATM 2354 O  O   . HOH H 6 .   ? -39.29649 -122.20282 8.79110   1.000 44.26625  ? 562 HOH A O   1 
HETATM 2355 O  O   . HOH H 6 .   ? -58.71887 -131.95384 -7.57176  1.000 31.29701  ? 563 HOH A O   1 
HETATM 2356 O  O   . HOH H 6 .   ? -38.93021 -122.18772 12.44666  1.000 46.38499  ? 564 HOH A O   1 
HETATM 2357 O  O   . HOH H 6 .   ? -50.06118 -114.80400 13.15972  1.000 46.47768  ? 565 HOH A O   1 
HETATM 2358 O  O   . HOH H 6 .   ? -56.12850 -115.53716 -4.29434  1.000 37.08609  ? 566 HOH A O   1 
HETATM 2359 O  O   . HOH H 6 .   ? -57.37090 -106.53601 -6.18448  1.000 65.63915  ? 567 HOH A O   1 
HETATM 2360 O  O   . HOH H 6 .   ? -58.96665 -138.26077 -3.45710  1.000 32.86293  ? 568 HOH A O   1 
HETATM 2361 O  O   . HOH H 6 .   ? -36.30453 -130.21294 -6.29861  1.000 55.56246  ? 569 HOH A O   1 
HETATM 2362 O  O   . HOH H 6 .   ? -41.54971 -108.60801 5.27046   1.000 55.17144  ? 570 HOH A O   1 
HETATM 2363 O  O   . HOH H 6 .   ? -78.57642 -112.36978 4.61041   1.000 53.99713  ? 571 HOH A O   1 
HETATM 2364 O  O   . HOH H 6 .   ? -36.70667 -125.78690 7.09995   1.000 49.15901  ? 572 HOH A O   1 
HETATM 2365 O  O   . HOH H 6 .   ? -64.88756 -116.55812 -1.12928  1.000 45.42023  ? 573 HOH A O   1 
HETATM 2366 O  O   . HOH H 6 .   ? -40.44404 -137.74736 -4.93049  1.000 38.26527  ? 574 HOH A O   1 
HETATM 2367 O  O   . HOH H 6 .   ? -52.44859 -118.63178 1.89309   1.000 35.85153  ? 575 HOH A O   1 
HETATM 2368 O  O   . HOH H 6 .   ? -67.48416 -123.94685 6.53864   1.000 46.80209  ? 576 HOH A O   1 
HETATM 2369 O  O   . HOH H 6 .   ? -54.46901 -143.87365 1.02647   1.000 36.54470  ? 577 HOH A O   1 
HETATM 2370 O  O   . HOH H 6 .   ? -50.43145 -137.65060 18.27894  1.000 46.16390  ? 578 HOH A O   1 
HETATM 2371 O  O   . HOH H 6 .   ? -35.30399 -111.29231 -11.20372 1.000 60.39110  ? 579 HOH A O   1 
HETATM 2372 O  O   . HOH H 6 .   ? -53.98000 -120.57754 14.49195  1.000 41.35451  ? 580 HOH A O   1 
HETATM 2373 O  O   . HOH H 6 .   ? -37.27983 -133.47890 3.97618   1.000 35.58803  ? 581 HOH A O   1 
HETATM 2374 O  O   . HOH H 6 .   ? -51.25974 -121.47441 -7.29154  1.000 32.50394  ? 582 HOH A O   1 
HETATM 2375 O  O   . HOH H 6 .   ? -48.99738 -144.38839 0.93261   1.000 51.97791  ? 583 HOH A O   1 
HETATM 2376 O  O   . HOH H 6 .   ? -37.62375 -128.15840 6.61853   1.000 45.56578  ? 584 HOH A O   1 
HETATM 2377 O  O   . HOH H 6 .   ? -50.21229 -110.19727 3.08064   1.000 54.28985  ? 585 HOH A O   1 
HETATM 2378 O  O   . HOH H 6 .   ? -70.225   -111.272   10.382    1.000 50.29921  ? 586 HOH A O   1 
HETATM 2379 O  O   . HOH H 6 .   ? -50.05170 -120.00951 -5.18135  1.000 36.13851  ? 587 HOH A O   1 
HETATM 2380 O  O   . HOH H 6 .   ? -51.28356 -141.90450 -5.34686  1.000 41.24106  ? 588 HOH A O   1 
HETATM 2381 O  O   . HOH H 6 .   ? -67.30978 -99.07051  -6.01672  1.000 60.84217  ? 589 HOH A O   1 
HETATM 2382 O  O   . HOH H 6 .   ? -35.22989 -118.11214 1.66169   1.000 50.65585  ? 590 HOH A O   1 
HETATM 2383 O  O   . HOH H 6 .   ? -54.72700 -131.67612 -12.54343 1.000 40.94604  ? 591 HOH A O   1 
HETATM 2384 O  O   . HOH H 6 .   ? -50.47881 -120.19606 -2.17063  1.000 34.21645  ? 592 HOH A O   1 
HETATM 2385 O  O   . HOH H 6 .   ? -38.74984 -137.75299 8.31125   1.000 46.26177  ? 593 HOH A O   1 
HETATM 2386 O  O   . HOH H 6 .   ? -55.79453 -141.60847 0.63405   1.000 32.55182  ? 594 HOH A O   1 
HETATM 2387 O  O   . HOH H 6 .   ? -37.09841 -128.80938 10.94905  1.000 50.07712  ? 595 HOH A O   1 
HETATM 2388 O  O   . HOH H 6 .   ? -56.00123 -132.70820 16.93129  1.000 46.11279  ? 596 HOH A O   1 
HETATM 2389 O  O   . HOH H 6 .   ? -45.35055 -145.57056 -1.19792  1.000 58.22471  ? 597 HOH A O   1 
HETATM 2390 O  O   . HOH H 6 .   ? -53.99334 -130.95502 -14.95370 1.000 58.34642  ? 598 HOH A O   1 
HETATM 2391 O  O   . HOH H 6 .   ? -34.87334 -132.17912 -6.09187  1.000 42.71706  ? 599 HOH A O   1 
HETATM 2392 O  O   . HOH H 6 .   ? -37.95446 -135.38977 8.29144   1.000 49.92090  ? 600 HOH A O   1 
HETATM 2393 O  O   . HOH H 6 .   ? -63.50852 -113.02364 -0.84998  1.000 46.12448  ? 601 HOH A O   1 
HETATM 2394 O  O   . HOH H 6 .   ? -43.23692 -115.82049 -17.87779 1.000 41.14108  ? 602 HOH A O   1 
HETATM 2395 O  O   . HOH H 6 .   ? -43.13209 -112.49249 -17.45169 1.000 45.11155  ? 603 HOH A O   1 
HETATM 2396 O  O   . HOH H 6 .   ? -42.784   -122.177   -18.934   1.000 60.90638  ? 604 HOH A O   1 
HETATM 2397 O  O   . HOH H 6 .   ? -51.29601 -110.95811 -13.07919 1.000 44.48550  ? 605 HOH A O   1 
HETATM 2398 O  O   . HOH H 6 .   ? -59.89866 -114.68299 -18.70323 1.000 47.43375  ? 606 HOH A O   1 
HETATM 2399 O  O   . HOH H 6 .   ? -62.88559 -116.69548 0.78187   1.000 50.53192  ? 607 HOH A O   1 
HETATM 2400 O  O   . HOH H 6 .   ? -73.09665 -101.53417 -7.91292  1.000 49.93486  ? 608 HOH A O   1 
HETATM 2401 O  O   . HOH H 6 .   ? -81.26222 -119.66180 -1.93280  1.000 57.56777  ? 609 HOH A O   1 
HETATM 2402 O  O   . HOH H 6 .   ? -54.86313 -109.86223 -7.51367  1.000 49.30148  ? 610 HOH A O   1 
HETATM 2403 O  O   . HOH H 6 .   ? -80.09208 -111.26245 0.60291   1.000 56.29251  ? 611 HOH A O   1 
HETATM 2404 O  O   . HOH H 6 .   ? -36.97396 -114.97623 -4.27455  1.000 47.92172  ? 612 HOH A O   1 
HETATM 2405 O  O   . HOH H 6 .   ? -40.717   -132.537   15.930    1.000 44.19602  ? 613 HOH A O   1 
HETATM 2406 O  O   . HOH H 6 .   ? -47.39211 -106.33927 -2.07297  1.000 44.53506  ? 614 HOH A O   1 
HETATM 2407 O  O   . HOH H 6 .   ? -48.40147 -111.94709 -13.20914 1.000 46.39902  ? 615 HOH A O   1 
HETATM 2408 O  O   . HOH H 6 .   ? -51.20784 -114.22815 8.11651   1.000 36.76473  ? 616 HOH A O   1 
HETATM 2409 O  O   . HOH H 6 .   ? -42.37202 -120.29283 -11.01184 1.000 40.86497  ? 617 HOH A O   1 
HETATM 2410 O  O   . HOH H 6 .   ? -43.86060 -130.64132 -11.74955 1.000 32.18084  ? 618 HOH A O   1 
HETATM 2411 O  O   . HOH H 6 .   ? -47.60505 -118.84289 -5.29322  1.000 28.74870  ? 619 HOH A O   1 
HETATM 2412 O  O   . HOH H 6 .   ? -74.65098 -119.62585 5.32238   1.000 50.88046  ? 620 HOH A O   1 
HETATM 2413 O  O   . HOH H 6 .   ? -34.43195 -117.70925 6.11461   1.000 56.49004  ? 621 HOH A O   1 
HETATM 2414 O  O   . HOH H 6 .   ? -44.89779 -111.75824 12.63904  1.000 54.78346  ? 622 HOH A O   1 
HETATM 2415 O  O   . HOH H 6 .   ? -47.58802 -110.16962 3.68477   1.000 32.99015  ? 623 HOH A O   1 
HETATM 2416 O  O   . HOH H 6 .   ? -47.68770 -114.44521 -17.89196 1.000 53.13051  ? 624 HOH A O   1 
HETATM 2417 O  O   . HOH H 6 .   ? -53.07130 -141.39956 10.81896  1.000 40.45289  ? 625 HOH A O   1 
HETATM 2418 O  O   . HOH H 6 .   ? -40.27836 -121.56871 -8.83414  1.000 27.39320  ? 626 HOH A O   1 
HETATM 2419 O  O   . HOH H 6 .   ? -34.76793 -125.65021 5.27467   1.000 42.25219  ? 627 HOH A O   1 
HETATM 2420 O  O   . HOH H 6 .   ? -54.31442 -143.26042 8.11659   1.000 36.17921  ? 628 HOH A O   1 
HETATM 2421 O  O   . HOH H 6 .   ? -59.60367 -108.65690 -8.68349  1.000 43.45611  ? 629 HOH A O   1 
HETATM 2422 O  O   . HOH H 6 .   ? -40.13153 -137.29247 -9.36194  1.000 43.21089  ? 630 HOH A O   1 
HETATM 2423 O  O   . HOH H 6 .   ? -66.88163 -125.79961 -19.75549 1.000 63.76648  ? 631 HOH A O   1 
HETATM 2424 O  O   . HOH H 6 .   ? -65.88317 -105.95016 -2.05406  1.000 39.64447  ? 632 HOH A O   1 
HETATM 2425 O  O   . HOH H 6 .   ? -64.58853 -141.48577 -6.98543  1.000 46.99784  ? 633 HOH A O   1 
HETATM 2426 O  O   . HOH H 6 .   ? -47.49880 -126.77132 -11.83527 1.000 45.60881  ? 634 HOH A O   1 
HETATM 2427 O  O   . HOH H 6 .   ? -59.63541 -137.84080 10.33827  1.000 34.85426  ? 635 HOH A O   1 
HETATM 2428 O  O   . HOH H 6 .   ? -65.38082 -131.80626 -10.85445 1.000 51.42261  ? 636 HOH A O   1 
HETATM 2429 O  O   . HOH H 6 .   ? -34.86015 -130.66407 -4.08736  1.000 52.15646  ? 637 HOH A O   1 
HETATM 2430 O  O   . HOH H 6 .   ? -73.23472 -130.72728 -4.90584  1.000 58.80192  ? 638 HOH A O   1 
HETATM 2431 O  O   . HOH H 6 .   ? -50.65096 -117.12172 0.91766   1.000 39.49112  ? 639 HOH A O   1 
HETATM 2432 O  O   . HOH H 6 .   ? -62.62626 -117.96534 2.83560   1.000 55.62936  ? 640 HOH A O   1 
HETATM 2433 O  O   . HOH H 6 .   ? -61.15763 -116.59954 4.12183   1.000 57.36744  ? 641 HOH A O   1 
HETATM 2434 O  O   . HOH H 6 .   ? -43.28997 -127.61050 -10.27231 1.000 33.73893  ? 642 HOH A O   1 
HETATM 2435 O  O   . HOH H 6 .   ? -57.42842 -117.20916 -21.50143 1.000 54.21048  ? 643 HOH A O   1 
HETATM 2436 O  O   . HOH H 6 .   ? -63.20799 -132.09149 -7.96338  1.000 44.53020  ? 644 HOH A O   1 
HETATM 2437 O  O   . HOH H 6 .   ? -58.02220 -113.34904 -20.14292 1.000 62.88970  ? 645 HOH A O   1 
HETATM 2438 O  O   . HOH H 6 .   ? -64.21902 -110.19542 -1.13926  1.000 66.85675  ? 646 HOH A O   1 
HETATM 2439 O  O   . HOH H 6 .   ? -48.82784 -118.06233 -1.21402  1.000 41.69484  ? 647 HOH A O   1 
HETATM 2440 O  O   . HOH H 6 .   ? -72.79203 -126.70330 -10.65749 1.000 52.12505  ? 648 HOH A O   1 
HETATM 2441 O  O   . HOH H 6 .   ? -31.79629 -110.44488 -9.82506  1.000 67.59643  ? 649 HOH A O   1 
HETATM 2442 O  O   . HOH H 6 .   ? -43.97028 -143.20063 -7.31721  1.000 58.86104  ? 650 HOH A O   1 
HETATM 2443 O  O   . HOH H 6 .   ? -65.85183 -124.97915 13.79487  1.000 57.00640  ? 651 HOH A O   1 
HETATM 2444 O  O   . HOH H 6 .   ? -60.33385 -116.96603 -20.27248 1.000 54.29878  ? 652 HOH A O   1 
HETATM 2445 O  O   . HOH H 6 .   ? -34.60882 -134.30130 -0.44035  1.000 60.27094  ? 653 HOH A O   1 
HETATM 2446 O  O   . HOH H 6 .   ? -41.89964 -125.76669 -8.45004  1.000 41.35623  ? 654 HOH A O   1 
HETATM 2447 O  O   . HOH H 6 .   ? -55.69920 -129.85048 17.03173  1.000 53.52647  ? 655 HOH A O   1 
HETATM 2448 O  O   . HOH H 6 .   ? -82.86312 -111.51123 0.62553   1.000 51.88598  ? 656 HOH A O   1 
HETATM 2449 O  O   . HOH H 6 .   ? -68.11310 -116.87933 -17.66638 1.000 55.33019  ? 657 HOH A O   1 
HETATM 2450 O  O   . HOH H 6 .   ? -33.91854 -118.00461 3.68822   1.000 58.52774  ? 658 HOH A O   1 
HETATM 2451 O  O   . HOH H 6 .   ? -47.60755 -116.92067 -3.32495  1.000 41.27346  ? 659 HOH A O   1 
HETATM 2452 O  O   . HOH H 6 .   ? -33.86449 -127.51113 3.81140   1.000 46.02654  ? 660 HOH A O   1 
HETATM 2453 O  O   . HOH H 6 .   ? -58.58491 -134.54011 -8.26580  1.000 47.66499  ? 661 HOH A O   1 
HETATM 2454 O  O   . HOH H 6 .   ? -39.10325 -138.67804 -2.99150  1.000 45.94884  ? 662 HOH A O   1 
HETATM 2455 O  O   . HOH H 6 .   ? -36.32135 -134.45873 6.41314   1.000 48.54407  ? 663 HOH A O   1 
HETATM 2456 O  O   . HOH H 6 .   ? -70.538   -112.770   12.568    1.000 49.20751  ? 664 HOH A O   1 
HETATM 2457 O  O   . HOH H 6 .   ? -38.92183 -137.96132 -7.28408  1.000 49.76871  ? 665 HOH A O   1 
HETATM 2458 O  O   . HOH I 6 .   ? -52.11942 -112.26189 6.37885   1.000 43.30765  ? 101 HOH B O   1 
HETATM 2459 O  O   . HOH I 6 .   ? -55.47790 -119.16008 8.29675   1.000 34.84181  ? 102 HOH B O   1 
HETATM 2460 O  O   . HOH I 6 .   ? -52.01679 -126.61654 17.98820  1.000 43.23770  ? 103 HOH B O   1 
HETATM 2461 O  O   . HOH I 6 .   ? -64.13732 -119.85176 12.05090  1.000 56.35589  ? 104 HOH B O   1 
HETATM 2462 O  O   . HOH I 6 .   ? -54.79301 -121.47819 11.31871  1.000 39.01208  ? 105 HOH B O   1 
HETATM 2463 O  O   . HOH I 6 .   ? -60.42822 -116.96562 13.97918  1.000 45.51044  ? 106 HOH B O   1 
HETATM 2464 O  O   . HOH I 6 .   ? -56.20010 -108.98657 0.56844   1.000 63.43206  ? 107 HOH B O   1 
HETATM 2465 O  O   . HOH I 6 .   ? -50.82983 -113.14694 10.80227  1.000 47.60508  ? 108 HOH B O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . PRO A 34  ? 1.08996 1.26233 1.49218 0.05357  -0.03442 -0.10365 33  PRO A N   
2    C CA  . PRO A 34  ? 1.11672 1.27988 1.51351 0.04745  -0.02961 -0.11359 33  PRO A CA  
3    C C   . PRO A 34  ? 1.07174 1.21766 1.43402 0.05055  -0.01948 -0.11375 33  PRO A C   
4    O O   . PRO A 34  ? 1.05226 1.18481 1.40108 0.05331  -0.00897 -0.11364 33  PRO A O   
5    C CB  . PRO A 34  ? 1.05027 1.20619 1.46890 0.03997  -0.02193 -0.12528 33  PRO A CB  
6    C CG  . PRO A 34  ? 1.01668 1.18653 1.46144 0.04077  -0.02922 -0.12110 33  PRO A CG  
7    C CD  . PRO A 34  ? 1.02075 1.19552 1.45043 0.04990  -0.03284 -0.10814 33  PRO A CD  
8    N N   . LEU A 35  ? 1.06973 1.21596 1.41802 0.05003  -0.02264 -0.11410 34  LEU A N   
9    C CA  . LEU A 35  ? 1.06817 1.19977 1.38273 0.05353  -0.01462 -0.11313 34  LEU A CA  
10   C C   . LEU A 35  ? 1.04306 1.15357 1.34959 0.04894  0.00093  -0.12419 34  LEU A C   
11   O O   . LEU A 35  ? 0.91824 1.01536 1.20724 0.05262  0.01099  -0.12283 34  LEU A O   
12   C CB  . LEU A 35  ? 0.98362 1.12137 1.28759 0.05340  -0.02218 -0.11164 34  LEU A CB  
13   N N   . GLU A 36  ? 1.08160 1.18892 1.40066 0.04092  0.00308  -0.13518 35  GLU A N   
14   C CA  . GLU A 36  ? 1.02306 1.11028 1.33355 0.03627  0.01768  -0.14607 35  GLU A CA  
15   C C   . GLU A 36  ? 1.01262 1.09129 1.33238 0.03559  0.02698  -0.14929 35  GLU A C   
16   O O   . GLU A 36  ? 0.95808 1.01838 1.26381 0.03428  0.04035  -0.15548 35  GLU A O   
17   C CB  . GLU A 36  ? 0.97927 1.06670 1.30528 0.02751  0.01708  -0.15717 35  GLU A CB  
18   N N   . SER A 37  ? 1.01976 1.11125 1.36249 0.03654  0.02027  -0.14520 36  SER A N   
19   C CA  . SER A 37  ? 1.00638 1.09139 1.36014 0.03592  0.02809  -0.14795 36  SER A CA  
20   C C   . SER A 37  ? 0.98077 1.06179 1.31618 0.04421  0.03142  -0.13833 36  SER A C   
21   O O   . SER A 37  ? 0.95417 1.02722 1.29387 0.04432  0.03961  -0.14045 36  SER A O   
22   C CB  . SER A 37  ? 0.99703 1.09764 1.38626 0.03238  0.01947  -0.14903 36  SER A CB  
23   N N   . GLN A 38  ? 0.90839 0.99481 1.22367 0.05114  0.02527  -0.12788 37  GLN A N   
24   C CA  . GLN A 38  ? 0.80435 0.88726 1.10060 0.05937  0.02795  -0.11822 37  GLN A CA  
25   C C   . GLN A 38  ? 0.75458 0.82164 1.01521 0.06319  0.03668  -0.11697 37  GLN A C   
26   O O   . GLN A 38  ? 0.70691 0.76620 0.94988 0.06914  0.04252  -0.11127 37  GLN A O   
27   C CB  . GLN A 38  ? 0.79380 0.89652 1.09537 0.06534  0.01347  -0.10575 37  GLN A CB  
28   C CG  . GLN A 38  ? 0.80368 0.90683 1.09661 0.07299  0.01442  -0.09601 37  GLN A CG  
29   C CD  . GLN A 38  ? 0.80558 0.92939 1.10752 0.07808  -0.00039 -0.08446 37  GLN A CD  
30   O OE1 . GLN A 38  ? 0.83084 0.96983 1.15392 0.07480  -0.01120 -0.08489 37  GLN A OE1 
31   N NE2 . GLN A 38  ? 0.68637 0.81081 0.97225 0.08613  -0.00092 -0.07410 37  GLN A NE2 
32   N N   . TYR A 39  ? 0.71533 0.77734 0.96510 0.05992  0.03775  -0.12217 38  TYR A N   
33   C CA  . TYR A 39  ? 0.63185 0.67880 0.84810 0.06300  0.04581  -0.12170 38  TYR A CA  
34   C C   . TYR A 39  ? 0.69495 0.72779 0.90900 0.05557  0.05520  -0.13450 38  TYR A C   
35   O O   . TYR A 39  ? 0.68941 0.72901 0.92256 0.04909  0.05039  -0.14115 38  TYR A O   
36   C CB  . TYR A 39  ? 0.64237 0.69936 0.84226 0.06824  0.03551  -0.11253 38  TYR A CB  
37   C CG  . TYR A 39  ? 0.54868 0.61878 0.74752 0.07611  0.02659  -0.09944 38  TYR A CG  
38   C CD1 . TYR A 39  ? 0.57805 0.66828 0.80247 0.07582  0.01353  -0.09498 38  TYR A CD1 
39   C CD2 . TYR A 39  ? 0.54707 0.60925 0.71971 0.08377  0.03142  -0.09165 38  TYR A CD2 
40   C CE1 . TYR A 39  ? 0.54358 0.64581 0.76755 0.08292  0.00547  -0.08313 38  TYR A CE1 
41   C CE2 . TYR A 39  ? 0.54583 0.61991 0.71781 0.09095  0.02343  -0.07977 38  TYR A CE2 
42   C CZ  . TYR A 39  ? 0.59311 0.68727 0.79087 0.09047  0.01044  -0.07556 38  TYR A CZ  
43   O OH  . TYR A 39  ? 0.56020 0.66634 0.75743 0.09757  0.00241  -0.06374 38  TYR A OH  
44   N N   . GLN A 40  ? 0.65905 0.67221 0.85003 0.05648  0.06868  -0.13799 39  GLN A N   
45   C CA  . GLN A 40  ? 0.68857 0.68757 0.86867 0.05110  0.07717  -0.14811 39  GLN A CA  
46   C C   . GLN A 40  ? 0.64299 0.64435 0.80042 0.05461  0.07173  -0.14295 39  GLN A C   
47   O O   . GLN A 40  ? 0.63089 0.63085 0.76513 0.06222  0.07118  -0.13359 39  GLN A O   
48   C CB  . GLN A 40  ? 0.70865 0.68575 0.87196 0.05092  0.09356  -0.15353 39  GLN A CB  
49   N N   . VAL A 41  ? 0.73216 0.73776 0.89672 0.04923  0.06724  -0.14875 40  VAL A N   
50   C CA  . VAL A 41  ? 0.67777 0.68687 0.82332 0.05191  0.06124  -0.14449 40  VAL A CA  
51   C C   . VAL A 41  ? 0.73846 0.72835 0.86184 0.04911  0.07294  -0.15255 40  VAL A C   
52   O O   . VAL A 41  ? 0.63695 0.61834 0.77103 0.04167  0.07994  -0.16399 40  VAL A O   
53   C CB  . VAL A 41  ? 0.71283 0.74066 0.88006 0.04830  0.04740  -0.14462 40  VAL A CB  
54   C CG1 . VAL A 41  ? 0.72883 0.76097 0.87522 0.05196  0.04076  -0.13901 40  VAL A CG1 
55   C CG2 . VAL A 41  ? 0.71159 0.75793 0.90302 0.05039  0.03644  -0.13756 40  VAL A CG2 
56   N N   . GLY A 42  ? 0.65312 0.63602 0.74551 0.05513  0.07519  -0.14660 41  GLY A N   
57   C CA  . GLY A 42  ? 0.67695 0.64207 0.74582 0.05333  0.08565  -0.15307 41  GLY A CA  
58   C C   . GLY A 42  ? 0.70570 0.67696 0.76464 0.05321  0.07803  -0.15194 41  GLY A C   
59   O O   . GLY A 42  ? 0.66968 0.65863 0.74598 0.05202  0.06529  -0.14934 41  GLY A O   
60   N N   . PRO A 43  ? 0.72529 0.68206 0.75565 0.05460  0.08567  -0.15367 42  PRO A N   
61   C CA  . PRO A 43  ? 0.73339 0.69386 0.75361 0.05368  0.07992  -0.15420 42  PRO A CA  
62   C C   . PRO A 43  ? 0.71571 0.68949 0.72329 0.06151  0.06840  -0.14148 42  PRO A C   
63   O O   . PRO A 43  ? 0.71077 0.68882 0.71297 0.06826  0.06602  -0.13198 42  PRO A O   
64   C CB  . PRO A 43  ? 0.74329 0.68178 0.73631 0.05285  0.09365  -0.16042 42  PRO A CB  
65   C CG  . PRO A 43  ? 0.79226 0.71924 0.76987 0.05835  0.10281  -0.15603 42  PRO A CG  
66   C CD  . PRO A 43  ? 0.80033 0.73626 0.80575 0.05719  0.10016  -0.15519 42  PRO A CD  
67   N N   . LEU A 44  ? 0.72027 0.70058 0.72331 0.06036  0.06127  -0.14170 43  LEU A N   
68   C CA  . LEU A 44  ? 0.72194 0.71371 0.71050 0.06723  0.05075  -0.13077 43  LEU A CA  
69   C C   . LEU A 44  ? 0.74064 0.72032 0.69576 0.07522  0.05759  -0.12381 43  LEU A C   
70   O O   . LEU A 44  ? 0.76037 0.72106 0.69566 0.07444  0.07004  -0.12924 43  LEU A O   
71   C CB  . LEU A 44  ? 0.72847 0.72437 0.71430 0.06368  0.04527  -0.13460 43  LEU A CB  
72   C CG  . LEU A 44  ? 0.72791 0.73843 0.70522 0.06827  0.03243  -0.12594 43  LEU A CG  
73   C CD1 . LEU A 44  ? 0.70314 0.73572 0.70403 0.07022  0.01846  -0.11815 43  LEU A CD1 
74   C CD2 . LEU A 44  ? 0.73559 0.74601 0.71282 0.06256  0.03045  -0.13340 43  LEU A CD2 
75   N N   . LEU A 45  ? 0.73428 0.72508 0.68332 0.08294  0.04939  -0.11172 44  LEU A N   
76   C CA  . LEU A 45  ? 0.75105 0.73331 0.66801 0.09131  0.05346  -0.10359 44  LEU A CA  
77   C C   . LEU A 45  ? 0.76360 0.74952 0.66051 0.09429  0.04729  -0.09972 44  LEU A C   
78   O O   . LEU A 45  ? 0.77238 0.77528 0.68198 0.09355  0.03473  -0.09692 44  LEU A O   
79   C CB  . LEU A 45  ? 0.73809 0.73063 0.65785 0.09846  0.04761  -0.09215 44  LEU A CB  
80   C CG  . LEU A 45  ? 0.73196 0.71746 0.65825 0.09952  0.05551  -0.09196 44  LEU A CG  
81   C CD1 . LEU A 45  ? 0.72036 0.71817 0.64634 0.10747  0.04753  -0.07921 44  LEU A CD1 
82   C CD2 . LEU A 45  ? 0.76275 0.72476 0.66421 0.10033  0.07143  -0.09636 44  LEU A CD2 
83   N N   . GLY A 46  ? 0.78728 0.75722 0.65273 0.09774  0.05614  -0.09950 45  GLY A N   
84   C CA  . GLY A 46  ? 0.80076 0.77313 0.64365 0.10182  0.05091  -0.09469 45  GLY A CA  
85   C C   . GLY A 46  ? 0.80074 0.77942 0.65223 0.09588  0.04505  -0.10095 45  GLY A C   
86   O O   . GLY A 46  ? 0.80598 0.79242 0.64516 0.09924  0.03705  -0.09571 45  GLY A O   
87   N N   . SER A 47  ? 0.79454 0.77052 0.66736 0.08714  0.04858  -0.11196 46  SER A N   
88   C CA  . SER A 47  ? 0.79396 0.77518 0.67704 0.08066  0.04377  -0.11905 46  SER A CA  
89   C C   . SER A 47  ? 0.77815 0.78216 0.67496 0.08205  0.02718  -0.11234 46  SER A C   
90   O O   . SER A 47  ? 0.78339 0.79192 0.67663 0.08006  0.02188  -0.11429 46  SER A O   
91   C CB  . SER A 47  ? 0.81964 0.78570 0.67451 0.08052  0.05130  -0.12334 46  SER A CB  
92   O OG  . SER A 47  ? 0.83271 0.77825 0.67978 0.07722  0.06646  -0.13181 46  SER A OG  
93   N N   . GLY A 48  ? 0.75845 0.77710 0.67173 0.08523  0.01884  -0.10466 47  GLY A N   
94   C CA  . GLY A 48  ? 0.74226 0.78287 0.66977 0.08664  0.00311  -0.09800 47  GLY A CA  
95   C C   . GLY A 48  ? 0.74743 0.79535 0.65354 0.09581  -0.00410 -0.08560 47  GLY A C   
96   O O   . GLY A 48  ? 0.73305 0.79998 0.65078 0.09774  -0.01752 -0.07893 47  GLY A O   
97   N N   . GLY A 49  ? 0.76741 0.80090 0.64277 0.10153  0.00436  -0.08229 48  GLY A N   
98   C CA  . GLY A 49  ? 0.77466 0.81361 0.62718 0.11030  -0.00171 -0.07096 48  GLY A CA  
99   C C   . GLY A 49  ? 0.75759 0.81071 0.61909 0.11629  -0.01004 -0.06002 48  GLY A C   
100  O O   . GLY A 49  ? 0.75826 0.82140 0.60757 0.12287  -0.01867 -0.05026 48  GLY A O   
101  N N   . PHE A 50  ? 0.74254 0.79657 0.62482 0.11420  -0.00754 -0.06149 49  PHE A N   
102  C CA  . PHE A 50  ? 0.72377 0.79210 0.61904 0.11889  -0.01567 -0.05201 49  PHE A CA  
103  C C   . PHE A 50  ? 0.69931 0.78780 0.62794 0.11442  -0.02812 -0.05243 49  PHE A C   
104  O O   . PHE A 50  ? 0.68192 0.78406 0.62408 0.11780  -0.03606 -0.04476 49  PHE A O   
105  C CB  . PHE A 50  ? 0.72146 0.77900 0.61949 0.11968  -0.00560 -0.05285 49  PHE A CB  
106  C CG  . PHE A 50  ? 0.74370 0.78227 0.60976 0.12484  0.00632  -0.05117 49  PHE A CG  
107  C CD1 . PHE A 50  ? 0.75220 0.79269 0.59407 0.13381  0.00305  -0.04029 49  PHE A CD1 
108  C CD2 . PHE A 50  ? 0.75575 0.77462 0.61630 0.12081  0.02082  -0.06036 49  PHE A CD2 
109  C CE1 . PHE A 50  ? 0.78104 0.80388 0.59334 0.13868  0.01409  -0.03863 49  PHE A CE1 
110  C CE2 . PHE A 50  ? 0.77622 0.77737 0.60742 0.12554  0.03197  -0.05882 49  PHE A CE2 
111  C CZ  . PHE A 50  ? 0.78484 0.78787 0.59175 0.13450  0.02863  -0.04793 49  PHE A CZ  
112  N N   . GLY A 51  ? 0.69778 0.78848 0.63951 0.10707  -0.03008 -0.06101 50  GLY A N   
113  C CA  . GLY A 51  ? 0.67525 0.78109 0.65104 0.10114  -0.03870 -0.06424 50  GLY A CA  
114  C C   . GLY A 51  ? 0.67177 0.76706 0.66522 0.09340  -0.02905 -0.07564 50  GLY A C   
115  O O   . GLY A 51  ? 0.68847 0.76481 0.66753 0.09149  -0.01613 -0.08248 50  GLY A O   
116  N N   . SER A 52  ? 0.42915 0.53395 0.53835 -0.10120 0.08144  0.00209  51  SER A N   
117  C CA  . SER A 52  ? 0.45183 0.56475 0.56825 -0.09239 0.07682  -0.01149 51  SER A CA  
118  C C   . SER A 52  ? 0.43953 0.56038 0.55494 -0.08026 0.06600  -0.01683 51  SER A C   
119  O O   . SER A 52  ? 0.43203 0.54798 0.53833 -0.06039 0.06218  -0.01543 51  SER A O   
120  C CB  . SER A 52  ? 0.40045 0.50285 0.51094 -0.07814 0.08142  -0.00990 51  SER A CB  
121  O OG  . SER A 52  ? 0.46686 0.55997 0.57636 -0.08960 0.09161  -0.00290 51  SER A OG  
122  N N   . VAL A 53  ? 0.40640 0.53933 0.53092 -0.09297 0.06091  -0.02296 52  VAL A N   
123  C CA  . VAL A 53  ? 0.42958 0.57055 0.55415 -0.08497 0.05050  -0.02805 52  VAL A CA  
124  C C   . VAL A 53  ? 0.41839 0.57502 0.55782 -0.09042 0.04490  -0.04379 52  VAL A C   
125  O O   . VAL A 53  ? 0.45321 0.61716 0.60333 -0.10957 0.04755  -0.04820 52  VAL A O   
126  C CB  . VAL A 53  ? 0.38618 0.52682 0.50775 -0.09482 0.04886  -0.02037 52  VAL A CB  
127  C CG1 . VAL A 53  ? 0.41954 0.56829 0.54146 -0.08653 0.03787  -0.02661 52  VAL A CG1 
128  C CG2 . VAL A 53  ? 0.37468 0.50051 0.48253 -0.08984 0.05503  -0.00465 52  VAL A CG2 
129  N N   . TYR A 54  ? 0.37681 0.53873 0.51685 -0.07382 0.03707  -0.05220 53  TYR A N   
130  C CA  . TYR A 54  ? 0.38572 0.56285 0.54023 -0.07621 0.03142  -0.06765 53  TYR A CA  
131  C C   . TYR A 54  ? 0.46199 0.64785 0.61754 -0.07028 0.02018  -0.07335 53  TYR A C   
132  O O   . TYR A 54  ? 0.41090 0.59006 0.55435 -0.05608 0.01581  -0.06734 53  TYR A O   
133  C CB  . TYR A 54  ? 0.42440 0.60141 0.58102 -0.06134 0.03155  -0.07441 53  TYR A CB  
134  C CG  . TYR A 54  ? 0.47962 0.64782 0.63574 -0.06577 0.04227  -0.07019 53  TYR A CG  
135  C CD1 . TYR A 54  ? 0.38946 0.54112 0.53126 -0.05786 0.04832  -0.05705 53  TYR A CD1 
136  C CD2 . TYR A 54  ? 0.47083 0.64718 0.64083 -0.07800 0.04652  -0.07957 53  TYR A CD2 
137  C CE1 . TYR A 54  ? 0.42908 0.57207 0.57034 -0.06211 0.05796  -0.05323 53  TYR A CE1 
138  C CE2 . TYR A 54  ? 0.44092 0.60862 0.61017 -0.08199 0.05630  -0.07608 53  TYR A CE2 
139  C CZ  . TYR A 54  ? 0.40693 0.55774 0.56181 -0.07392 0.06180  -0.06292 53  TYR A CZ  
140  O OH  . TYR A 54  ? 0.35670 0.49821 0.51069 -0.07812 0.07142  -0.05938 53  TYR A OH  
141  N N   . SER A 55  ? 0.38831 0.58908 0.55828 -0.08117 0.01562  -0.08526 54  SER A N   
142  C CA  . SER A 55  ? 0.42794 0.63800 0.60059 -0.07550 0.00445  -0.09251 54  SER A CA  
143  C C   . SER A 55  ? 0.56691 0.77941 0.73848 -0.05384 -0.00217 -0.09984 54  SER A C   
144  O O   . SER A 55  ? 0.44093 0.65434 0.61717 -0.04835 0.00095  -0.10460 54  SER A O   
145  C CB  . SER A 55  ? 0.52069 0.74600 0.70952 -0.09407 0.00185  -0.10317 54  SER A CB  
146  O OG  . SER A 55  ? 0.57465 0.80951 0.76727 -0.08802 -0.00929 -0.11148 54  SER A OG  
147  N N   . GLY A 56  ? 0.43066 0.64382 0.59573 -0.04121 -0.01159 -0.10071 55  GLY A N   
148  C CA  . GLY A 56  ? 0.45667 0.67163 0.61923 -0.02010 -0.01896 -0.10709 55  GLY A CA  
149  C C   . GLY A 56  ? 0.48772 0.71045 0.65066 -0.01401 -0.03092 -0.11359 55  GLY A C   
150  O O   . GLY A 56  ? 0.50608 0.73066 0.66913 -0.02462 -0.03323 -0.11166 55  GLY A O   
151  N N   . ILE A 57  ? 0.48194 0.70888 0.64505 0.00352  -0.03881 -0.12144 56  ILE A N   
152  C CA  . ILE A 57  ? 0.42698 0.66064 0.58936 0.01238  -0.05103 -0.12828 56  ILE A CA  
153  C C   . ILE A 57  ? 0.55988 0.78586 0.70877 0.03719  -0.05614 -0.12658 56  ILE A C   
154  O O   . ILE A 57  ? 0.56022 0.78662 0.71178 0.04699  -0.05527 -0.13024 56  ILE A O   
155  C CB  . ILE A 57  ? 0.53424 0.78689 0.71671 0.00434  -0.05760 -0.14422 56  ILE A CB  
156  C CG1 . ILE A 57  ? 0.52120 0.78092 0.71445 -0.02003 -0.05446 -0.14545 56  ILE A CG1 
157  C CG2 . ILE A 57  ? 0.61589 0.87488 0.79715 0.01871  -0.07092 -0.15239 56  ILE A CG2 
158  N N   . ARG A 58  ? 0.51779 0.73622 0.65174 0.04749  -0.06129 -0.12087 57  ARG A N   
159  C CA  . ARG A 58  ? 0.59149 0.80323 0.71176 0.07113  -0.06739 -0.12004 57  ARG A CA  
160  C C   . ARG A 58  ? 0.68237 0.90841 0.81375 0.07890  -0.07914 -0.13519 57  ARG A C   
161  O O   . ARG A 58  ? 0.70256 0.93852 0.84088 0.07332  -0.08709 -0.14278 57  ARG A O   
162  C CB  . ARG A 58  ? 0.57562 0.77629 0.67721 0.07932  -0.06978 -0.11074 57  ARG A CB  
163  C CG  . ARG A 58  ? 0.69086 0.88247 0.77539 0.10367  -0.07489 -0.10819 57  ARG A CG  
164  C CD  . ARG A 58  ? 0.63207 0.80913 0.69618 0.11026  -0.07224 -0.09531 57  ARG A CD  
165  N NE  . ARG A 58  ? 0.68882 0.87011 0.75297 0.10443  -0.07841 -0.09761 57  ARG A NE  
166  C CZ  . ARG A 58  ? 0.65154 0.82271 0.70148 0.10617  -0.07621 -0.08772 57  ARG A CZ  
167  N NH1 . ARG A 58  ? 0.62007 0.77677 0.65499 0.11242  -0.06748 -0.07447 57  ARG A NH1 
168  N NH2 . ARG A 58  ? 0.65942 0.83507 0.71058 0.10149  -0.08281 -0.09129 57  ARG A NH2 
169  N N   . VAL A 59  ? 0.71613 0.94326 0.84976 0.09153  -0.08035 -0.13964 58  VAL A N   
170  C CA  . VAL A 59  ? 0.76974 1.01189 0.91671 0.09794  -0.09095 -0.15458 58  VAL A CA  
171  C C   . VAL A 59  ? 0.85630 1.09885 0.99341 0.11190  -0.10348 -0.15772 58  VAL A C   
172  O O   . VAL A 59  ? 0.82307 1.07973 0.97219 0.11006  -0.11319 -0.16984 58  VAL A O   
173  C CB  . VAL A 59  ? 0.73014 0.97180 0.88041 0.11003  -0.08950 -0.15756 58  VAL A CB  
174  C CG2 . VAL A 59  ? 0.68287 0.92711 0.84635 0.09436  -0.07807 -0.15751 58  VAL A CG2 
175  N N   . SER A 60  ? 0.84484 1.07189 0.95983 0.12556  -0.10330 -0.14693 59  SER A N   
176  C CA  . SER A 60  ? 0.93790 1.16387 1.04132 0.14101  -0.11507 -0.14977 59  SER A CA  
177  C C   . SER A 60  ? 0.93103 1.16451 1.03922 0.13009  -0.12111 -0.15449 59  SER A C   
178  O O   . SER A 60  ? 0.96626 1.20323 1.07029 0.14051  -0.13262 -0.16092 59  SER A O   
179  C CB  . SER A 60  ? 0.97344 1.18043 1.05125 0.15657  -0.11206 -0.13633 59  SER A CB  
180  O OG  . SER A 60  ? 0.92885 1.12616 0.99914 0.14525  -0.10224 -0.12438 59  SER A OG  
181  N N   . ASP A 61  ? 0.84357 1.07920 0.96004 0.10952  -0.11404 -0.15153 60  ASP A N   
182  C CA  . ASP A 61  ? 0.79363 1.03506 0.91395 0.09911  -0.11973 -0.15530 60  ASP A CA  
183  C C   . ASP A 61  ? 0.71876 0.96872 0.85628 0.07434  -0.11362 -0.15720 60  ASP A C   
184  O O   . ASP A 61  ? 0.73344 0.98612 0.87355 0.06317  -0.11637 -0.15806 60  ASP A O   
185  C CB  . ASP A 61  ? 0.81650 1.04328 0.91585 0.10574  -0.11900 -0.14401 60  ASP A CB  
186  C CG  . ASP A 61  ? 0.80720 1.02281 0.90056 0.09491  -0.10575 -0.13000 60  ASP A CG  
187  O OD1 . ASP A 61  ? 0.70581 0.91984 0.80410 0.08971  -0.09661 -0.12636 60  ASP A OD1 
188  O OD2 . ASP A 61  ? 0.72521 0.93355 0.80902 0.09178  -0.10464 -0.12273 60  ASP A OD2 
189  N N   . ASN A 62  ? 0.70167 0.95546 0.85056 0.06570  -0.10545 -0.15793 61  ASN A N   
190  C CA  . ASN A 62  ? 0.72651 0.98800 0.89116 0.04212  -0.09863 -0.15959 61  ASN A CA  
191  C C   . ASN A 62  ? 0.68704 0.93827 0.84339 0.02948  -0.09117 -0.14729 61  ASN A C   
192  O O   . ASN A 62  ? 0.66948 0.92683 0.83703 0.00944  -0.08800 -0.14865 61  ASN A O   
193  C CB  . ASN A 62  ? 0.70693 0.98611 0.88995 0.03202  -0.10710 -0.17395 61  ASN A CB  
194  C CG  . ASN A 62  ? 0.70850 1.00099 0.90688 0.03664  -0.11035 -0.18639 61  ASN A CG  
195  N N   . LEU A 63  ? 0.62304 0.85879 0.76012 0.04053  -0.08801 -0.13507 62  LEU A N   
196  C CA  . LEU A 63  ? 0.60761 0.83364 0.73732 0.02925  -0.08050 -0.12287 62  LEU A CA  
197  C C   . LEU A 63  ? 0.51681 0.74119 0.65338 0.01420  -0.06830 -0.11739 62  LEU A C   
198  O O   . LEU A 63  ? 0.53701 0.75782 0.67227 0.02094  -0.06290 -0.11569 62  LEU A O   
199  C CB  . LEU A 63  ? 0.58761 0.79786 0.69550 0.04532  -0.07920 -0.11115 62  LEU A CB  
200  C CG  . LEU A 63  ? 0.56432 0.76442 0.66451 0.03515  -0.07140 -0.09804 62  LEU A CG  
201  C CD1 . LEU A 63  ? 0.48620 0.68904 0.58671 0.02915  -0.07837 -0.10001 62  LEU A CD1 
202  C CD2 . LEU A 63  ? 0.52832 0.71252 0.60893 0.05003  -0.06560 -0.08523 62  LEU A CD2 
203  N N   . PRO A 64  ? 0.52557 0.75202 0.66916 -0.00608 -0.06393 -0.11457 63  PRO A N   
204  C CA  . PRO A 64  ? 0.47989 0.70317 0.62785 -0.02052 -0.05212 -0.10816 63  PRO A CA  
205  C C   . PRO A 64  ? 0.49388 0.70061 0.62543 -0.01401 -0.04381 -0.09283 63  PRO A C   
206  O O   . PRO A 64  ? 0.46350 0.66209 0.58336 -0.00995 -0.04497 -0.08475 63  PRO A O   
207  C CB  . PRO A 64  ? 0.56820 0.79806 0.72653 -0.04298 -0.05180 -0.10944 63  PRO A CB  
208  C CG  . PRO A 64  ? 0.55339 0.78335 0.70632 -0.03785 -0.06146 -0.11066 63  PRO A CG  
209  C CD  . PRO A 64  ? 0.54764 0.78044 0.69684 -0.01737 -0.07035 -0.11850 63  PRO A CD  
210  N N   . VAL A 65  ? 0.43082 0.63263 0.56201 -0.01343 -0.03511 -0.08896 64  VAL A N   
211  C CA  . VAL A 65  ? 0.40823 0.59455 0.52502 -0.00792 -0.02639 -0.07466 64  VAL A CA  
212  C C   . VAL A 65  ? 0.44072 0.62524 0.56433 -0.02435 -0.01534 -0.07028 64  VAL A C   
213  O O   . VAL A 65  ? 0.44456 0.63895 0.58252 -0.03523 -0.01417 -0.07912 64  VAL A O   
214  C CB  . VAL A 65  ? 0.44865 0.62704 0.55348 0.01493  -0.02732 -0.07295 64  VAL A CB  
215  C CG1 . VAL A 65  ? 0.38496 0.56398 0.48094 0.03213  -0.03835 -0.07680 64  VAL A CG1 
216  C CG2 . VAL A 65  ? 0.41015 0.59492 0.52566 0.01666  -0.02617 -0.08186 64  VAL A CG2 
217  N N   . ALA A 66  ? 0.36888 0.54058 0.48187 -0.02582 -0.00704 -0.05655 65  ALA A N   
218  C CA  . ALA A 66  ? 0.35479 0.52156 0.47068 -0.03754 0.00398  -0.05069 65  ALA A CA  
219  C C   . ALA A 66  ? 0.40811 0.56275 0.51223 -0.02118 0.00904  -0.04401 65  ALA A C   
220  O O   . ALA A 66  ? 0.39838 0.54363 0.48785 -0.00613 0.00770  -0.03652 65  ALA A O   
221  C CB  . ALA A 66  ? 0.36184 0.52339 0.47577 -0.05352 0.00985  -0.03985 65  ALA A CB  
222  N N   . ILE A 67  ? 0.34989 0.50442 0.46007 -0.02401 0.01487  -0.04681 66  ILE A N   
223  C CA  . ILE A 67  ? 0.38589 0.52951 0.48653 -0.00847 0.01910  -0.04216 66  ILE A CA  
224  C C   . ILE A 67  ? 0.39500 0.52862 0.49358 -0.01967 0.03113  -0.03186 66  ILE A C   
225  O O   . ILE A 67  ? 0.41743 0.55577 0.52750 -0.03419 0.03607  -0.03627 66  ILE A O   
226  C CB  . ILE A 67  ? 0.43805 0.58939 0.54744 0.00019  0.01500  -0.05479 66  ILE A CB  
227  C CG1 . ILE A 67  ? 0.40041 0.56303 0.51334 0.00927  0.00251  -0.06551 66  ILE A CG1 
228  C CG2 . ILE A 67  ? 0.41317 0.55213 0.51167 0.01744  0.01861  -0.04954 66  ILE A CG2 
229  C CD1 . ILE A 67  ? 0.52457 0.69739 0.64865 0.01674  -0.00266 -0.07918 66  ILE A CD1 
230  N N   . LYS A 68  ? 0.38054 0.50043 0.46451 -0.01322 0.03601  -0.01827 67  LYS A N   
231  C CA  . LYS A 68  ? 0.37486 0.48464 0.45596 -0.02392 0.04715  -0.00720 67  LYS A CA  
232  C C   . LYS A 68  ? 0.41645 0.51340 0.48776 -0.00994 0.05270  -0.00163 67  LYS A C   
233  O O   . LYS A 68  ? 0.40429 0.49403 0.46277 0.00885  0.04977  0.00227  67  LYS A O   
234  C CB  . LYS A 68  ? 0.39155 0.49536 0.46460 -0.02919 0.04954  0.00497  67  LYS A CB  
235  C CG  . LYS A 68  ? 0.39045 0.48320 0.45975 -0.03904 0.06088  0.01739  67  LYS A CG  
236  C CD  . LYS A 68  ? 0.42796 0.51703 0.49183 -0.04544 0.06256  0.02841  67  LYS A CD  
237  C CE  . LYS A 68  ? 0.52005 0.60069 0.58340 -0.05901 0.07320  0.03962  67  LYS A CE  
238  N NZ  . LYS A 68  ? 0.44165 0.51903 0.50015 -0.06403 0.07458  0.05064  67  LYS A NZ  
239  N N   . HIS A 69  ? 0.39998 0.49350 0.47675 -0.01948 0.06080  -0.00099 68  HIS A N   
240  C CA  . HIS A 69  ? 0.39678 0.47779 0.46596 -0.00871 0.06681  0.00385  68  HIS A CA  
241  C C   . HIS A 69  ? 0.39748 0.46595 0.45994 -0.01787 0.07735  0.01789  68  HIS A C   
242  O O   . HIS A 69  ? 0.45461 0.52630 0.52504 -0.03745 0.08195  0.01918  68  HIS A O   
243  C CB  . HIS A 69  ? 0.39994 0.48645 0.48133 -0.01166 0.06793  -0.00740 68  HIS A CB  
244  C CG  . HIS A 69  ? 0.39567 0.49553 0.48566 -0.00343 0.05791  -0.02178 68  HIS A CG  
245  N ND1 . HIS A 69  ? 0.42651 0.52429 0.51364 0.01538  0.05390  -0.02677 68  HIS A ND1 
246  C CD2 . HIS A 69  ? 0.38358 0.49910 0.48521 -0.01154 0.05087  -0.03218 68  HIS A CD2 
247  C CE1 . HIS A 69  ? 0.45624 0.56847 0.55355 0.01845  0.04476  -0.03987 68  HIS A CE1 
248  N NE2 . HIS A 69  ? 0.44241 0.56552 0.54852 0.00226  0.04287  -0.04335 68  HIS A NE2 
249  N N   . VAL A 70  ? 0.41198 0.46614 0.45976 -0.00398 0.08113  0.02839  69  VAL A N   
250  C CA  . VAL A 70  ? 0.44684 0.48828 0.48778 -0.01099 0.09134  0.04208  69  VAL A CA  
251  C C   . VAL A 70  ? 0.45079 0.47908 0.48435 0.00044  0.09675  0.04561  69  VAL A C   
252  O O   . VAL A 70  ? 0.50285 0.52686 0.52775 0.01988  0.09247  0.04438  69  VAL A O   
253  C CB  . VAL A 70  ? 0.59203 0.62817 0.62131 -0.00689 0.09153  0.05386  69  VAL A CB  
254  C CG1 . VAL A 70  ? 0.66243 0.68517 0.68462 -0.01238 0.10220  0.06811  69  VAL A CG1 
255  C CG2 . VAL A 70  ? 0.48494 0.53336 0.52269 -0.02023 0.08676  0.05064  69  VAL A CG2 
256  N N   . GLU A 71  ? 0.53238 0.55402 0.56921 -0.01169 0.10583  0.04983  70  GLU A N   
257  C CA  . GLU A 71  ? 0.61750 0.62672 0.64950 -0.00356 0.11146  0.05212  70  GLU A CA  
258  C C   . GLU A 71  ? 0.64471 0.63752 0.66020 0.00564  0.11732  0.06763  70  GLU A C   
259  O O   . GLU A 71  ? 0.59602 0.58507 0.60912 -0.00530 0.12297  0.07781  70  GLU A O   
260  C CB  . GLU A 71  ? 0.68634 0.69585 0.72955 -0.02179 0.11863  0.04907  70  GLU A CB  
261  C CG  . GLU A 71  ? 0.73907 0.74000 0.78248 -0.01492 0.12258  0.04581  70  GLU A CG  
262  C CD  . GLU A 71  ? 0.77197 0.77621 0.82825 -0.03372 0.12837  0.03981  70  GLU A CD  
263  O OE1 . GLU A 71  ? 0.70525 0.72409 0.77397 -0.04712 0.12518  0.03061  70  GLU A OE1 
264  O OE2 . GLU A 71  ? 0.84746 0.83934 0.90097 -0.03537 0.13620  0.04433  70  GLU A OE2 
265  N N   . LYS A 72  ? 0.65803 0.64120 0.66225 0.02565  0.11592  0.06949  71  LYS A N   
266  C CA  . LYS A 72  ? 0.71588 0.68306 0.70325 0.03577  0.12142  0.08414  71  LYS A CA  
267  C C   . LYS A 72  ? 0.78157 0.73799 0.76881 0.02224  0.13282  0.09427  71  LYS A C   
268  O O   . LYS A 72  ? 0.78740 0.73683 0.76652 0.01960  0.13808  0.10682  71  LYS A O   
269  C CB  . LYS A 72  ? 0.71951 0.67685 0.69565 0.05784  0.11881  0.08381  71  LYS A CB  
270  C CG  . LYS A 72  ? 0.67447 0.64004 0.64749 0.07395  0.10743  0.07568  71  LYS A CG  
271  C CD  . LYS A 72  ? 0.69270 0.64638 0.65275 0.09575  0.10544  0.07735  71  LYS A CD  
272  C CE  . LYS A 72  ? 0.67883 0.63951 0.63351 0.11250  0.09400  0.07072  71  LYS A CE  
273  N NZ  . LYS A 72  ? 0.70328 0.65350 0.64670 0.13339  0.09091  0.07082  71  LYS A NZ  
274  N N   . ASP A 73  ? 0.84208 0.79704 0.83839 0.01370  0.13681  0.08880  72  ASP A N   
275  C CA  . ASP A 73  ? 0.91605 0.86076 0.91296 0.00011  0.14735  0.09723  72  ASP A CA  
276  C C   . ASP A 73  ? 0.87827 0.82871 0.88037 -0.01894 0.15054  0.10291  72  ASP A C   
277  O O   . ASP A 73  ? 0.86883 0.80944 0.86742 -0.02747 0.15895  0.11388  72  ASP A O   
278  C CB  . ASP A 73  ? 0.92456 0.86976 0.93254 -0.00774 0.14995  0.08772  72  ASP A CB  
279  C CG  . ASP A 73  ? 1.04875 0.98346 1.05067 0.00981  0.14964  0.08537  72  ASP A CG  
280  O OD1 . ASP A 73  ? 1.05871 0.98399 1.04650 0.02739  0.14822  0.09254  72  ASP A OD1 
281  O OD2 . ASP A 73  ? 1.04564 0.98140 1.05685 0.00599  0.15085  0.07628  72  ASP A OD2 
282  N N   . ARG A 74  ? 0.81406 0.77997 0.82461 -0.02584 0.14383  0.09580  73  ARG A N   
283  C CA  . ARG A 74  ? 0.85969 0.83215 0.87675 -0.04480 0.14586  0.09983  73  ARG A CA  
284  C C   . ARG A 74  ? 0.78920 0.76180 0.79802 -0.03994 0.14415  0.10936  73  ARG A C   
285  O O   . ARG A 74  ? 0.87235 0.85074 0.88650 -0.05445 0.14498  0.11302  73  ARG A O   
286  C CB  . ARG A 74  ? 0.75904 0.74818 0.79110 -0.05760 0.13999  0.08645  73  ARG A CB  
287  C CG  . ARG A 74  ? 0.78830 0.77893 0.83030 -0.06589 0.14258  0.07667  73  ARG A CG  
288  C CD  . ARG A 74  ? 0.79016 0.79668 0.84663 -0.08290 0.13875  0.06599  73  ARG A CD  
289  N NE  . ARG A 74  ? 0.87921 0.88627 0.94489 -0.09452 0.14329  0.05845  73  ARG A NE  
290  C CZ  . ARG A 74  ? 0.84121 0.85876 0.91721 -0.09537 0.13926  0.04415  73  ARG A CZ  
291  N NH1 . ARG A 74  ? 0.76941 0.79834 0.84860 -0.08598 0.13017  0.03553  73  ARG A NH1 
292  N NH2 . ARG A 74  ? 0.73375 0.75057 0.81730 -0.10618 0.14455  0.03815  73  ARG A NH2 
293  N N   . ILE A 75  ? 0.83867 0.80492 0.83454 -0.02005 0.14182  0.11346  74  ILE A N   
294  C CA  . ILE A 75  ? 0.79033 0.75784 0.77824 -0.01370 0.13937  0.12073  74  ILE A CA  
295  C C   . ILE A 75  ? 0.90967 0.86404 0.88795 -0.01434 0.14876  0.13668  74  ILE A C   
296  O O   . ILE A 75  ? 0.95044 0.89142 0.91840 -0.00361 0.15370  0.14273  74  ILE A O   
297  C CB  . ILE A 75  ? 0.81247 0.78077 0.79089 0.00805  0.13144  0.11617  74  ILE A CB  
298  C CG1 . ILE A 75  ? 0.78815 0.77216 0.77767 0.00650  0.12136  0.10089  74  ILE A CG1 
299  C CG2 . ILE A 75  ? 0.77936 0.74433 0.74560 0.01725  0.13128  0.12619  74  ILE A CG2 
300  C CD1 . ILE A 75  ? 0.75467 0.73916 0.73757 0.02694  0.11359  0.09355  74  ILE A CD1 
301  N N   . SER A 76  ? 0.97658 0.93482 0.95844 -0.02682 0.15109  0.14358  75  SER A N   
302  C CA  . SER A 76  ? 1.05866 1.00628 1.03355 -0.02942 0.16010  0.15868  75  SER A CA  
303  C C   . SER A 76  ? 0.94946 0.89255 0.91047 -0.01308 0.15966  0.16693  75  SER A C   
304  O O   . SER A 76  ? 0.99818 0.92893 0.94898 -0.00752 0.16724  0.17864  75  SER A O   
305  C CB  . SER A 76  ? 1.04853 1.00250 1.03453 -0.05099 0.16299  0.16264  75  SER A CB  
306  N N   . ASP A 77  ? 0.81470 0.76717 0.77478 -0.00536 0.15117  0.16108  76  ASP A N   
307  C CA  . ASP A 77  ? 0.83752 0.78712 0.78528 0.00809  0.15068  0.16857  76  ASP A CA  
308  C C   . ASP A 77  ? 0.78888 0.73947 0.72748 0.02795  0.14238  0.16065  76  ASP A C   
309  O O   . ASP A 77  ? 0.75079 0.71245 0.69697 0.02752  0.13346  0.14822  76  ASP A O   
310  C CB  . ASP A 77  ? 0.88363 0.84332 0.83846 -0.00230 0.14856  0.17068  76  ASP A CB  
311  C CG  . ASP A 77  ? 0.84873 0.80292 0.79195 0.00716  0.15243  0.18246  76  ASP A CG  
312  N N   . TRP A 78  ? 0.83699 0.77602 0.75915 0.04504  0.14527  0.16798  77  TRP A N   
313  C CA  . TRP A 78  ? 0.79852 0.73611 0.70936 0.06533  0.13800  0.16210  77  TRP A CA  
314  C C   . TRP A 78  ? 0.80610 0.74224 0.70402 0.07722  0.13705  0.16853  77  TRP A C   
315  O O   . TRP A 78  ? 0.91543 0.84745 0.80997 0.07296  0.14441  0.18004  77  TRP A O   
316  C CB  . TRP A 78  ? 0.82935 0.75323 0.73001 0.07705  0.14160  0.16459  77  TRP A CB  
317  C CG  . TRP A 78  ? 0.83983 0.76532 0.75255 0.06811  0.14144  0.15643  77  TRP A CG  
318  C CD1 . TRP A 78  ? 0.80887 0.73150 0.73096 0.05157  0.14908  0.15985  77  TRP A CD1 
319  C CD2 . TRP A 78  ? 0.71933 0.65008 0.63646 0.07506  0.13325  0.14305  77  TRP A CD2 
320  N NE1 . TRP A 78  ? 0.81490 0.74037 0.74650 0.04789  0.14648  0.14930  77  TRP A NE1 
321  C CE2 . TRP A 78  ? 0.82671 0.75754 0.75604 0.06213  0.13687  0.13887  77  TRP A CE2 
322  C CE3 . TRP A 78  ? 0.76408 0.69975 0.67635 0.09087  0.12312  0.13402  77  TRP A CE3 
323  C CZ2 . TRP A 78  ? 0.80069 0.73670 0.73798 0.06471  0.13109  0.12596  77  TRP A CZ2 
324  C CZ3 . TRP A 78  ? 0.82314 0.76416 0.74367 0.09336  0.11700  0.12140  77  TRP A CZ3 
325  C CH2 . TRP A 78  ? 0.79991 0.74127 0.73312 0.08039  0.12120  0.11745  77  TRP A CH2 
326  N N   . GLY A 79  ? 0.80181 0.74149 0.69260 0.09239  0.12787  0.16073  78  GLY A N   
327  C CA  . GLY A 79  ? 0.74214 0.68020 0.61925 0.10557  0.12603  0.16519  78  GLY A CA  
328  C C   . GLY A 79  ? 0.88614 0.81993 0.74918 0.12664  0.11901  0.15981  78  GLY A C   
329  O O   . GLY A 79  ? 0.88872 0.82103 0.75344 0.13104  0.11555  0.15286  78  GLY A O   
330  N N   . GLU A 80  ? 0.88998 0.82171 0.73891 0.13993  0.11685  0.16305  79  GLU A N   
331  C CA  . GLU A 80  ? 0.97251 0.90011 0.80609 0.16068  0.10963  0.15853  79  GLU A CA  
332  C C   . GLU A 80  ? 0.96486 0.90441 0.80049 0.16457  0.09875  0.14849  79  GLU A C   
333  O O   . GLU A 80  ? 0.91457 0.85933 0.75270 0.15861  0.09973  0.15125  79  GLU A O   
334  C CB  . GLU A 80  ? 1.01721 0.92985 0.82894 0.17506  0.11670  0.17135  79  GLU A CB  
335  N N   . LEU A 81  ? 1.00331 0.94725 0.83856 0.17434  0.08826  0.13670  80  LEU A N   
336  C CA  . LEU A 81  ? 1.00857 0.96268 0.84399 0.18015  0.07715  0.12668  80  LEU A CA  
337  C C   . LEU A 81  ? 1.18289 1.12931 0.99720 0.19636  0.07744  0.13329  80  LEU A C   
338  O O   . LEU A 81  ? 1.13026 1.06339 0.92919 0.20488  0.08531  0.14448  80  LEU A O   
339  C CB  . LEU A 81  ? 1.05234 1.01238 0.89223 0.18732  0.06624  0.11296  80  LEU A CB  
340  C CG  . LEU A 81  ? 0.88844 0.86168 0.75150 0.17093  0.06242  0.10205  80  LEU A CG  
341  N N   . PRO A 82  ? 1.23914 1.19349 1.05196 0.20074  0.06909  0.12653  81  PRO A N   
342  C CA  . PRO A 82  ? 1.32659 1.27379 1.11856 0.21685  0.06889  0.13171  81  PRO A CA  
343  C C   . PRO A 82  ? 1.33339 1.26810 1.10499 0.23625  0.06833  0.13468  81  PRO A C   
344  O O   . PRO A 82  ? 1.41797 1.34309 1.17010 0.24848  0.07219  0.14291  81  PRO A O   
345  C CB  . PRO A 82  ? 1.31342 1.27236 1.10967 0.21880  0.05691  0.11964  81  PRO A CB  
346  C CG  . PRO A 82  ? 1.15742 1.12876 0.97737 0.19832  0.05596  0.11416  81  PRO A CG  
347  C CD  . PRO A 82  ? 1.25761 1.22733 1.08802 0.18924  0.06082  0.11507  81  PRO A CD  
348  N N   . ASN A 83  ? 1.27868 1.21313 1.05435 0.23926  0.06379  0.12827  82  ASN A N   
349  C CA  . ASN A 83  ? 1.26183 1.18426 1.01932 0.25735  0.06248  0.13071  82  ASN A CA  
350  C C   . ASN A 83  ? 1.23622 1.14746 0.99325 0.25400  0.07251  0.13992  82  ASN A C   
351  O O   . ASN A 83  ? 1.23606 1.13849 0.98297 0.26642  0.07052  0.14005  82  ASN A O   
352  C CB  . ASN A 83  ? 1.26094 1.19063 1.02158 0.26635  0.04859  0.11625  82  ASN A CB  
353  C CG  . ASN A 83  ? 1.24642 1.18797 1.03164 0.25174  0.04526  0.10620  82  ASN A CG  
354  O OD1 . ASN A 83  ? 1.23124 1.16934 1.02056 0.25259  0.04598  0.10484  82  ASN A OD1 
355  N ND2 . ASN A 83  ? 1.21993 1.17527 1.02148 0.23820  0.04176  0.09911  82  ASN A ND2 
356  N N   . GLY A 84  ? 1.28192 1.19310 1.04986 0.23741  0.08292  0.14750  83  GLY A N   
357  C CA  . GLY A 84  ? 1.24098 1.14040 1.00725 0.23362  0.09355  0.15762  83  GLY A CA  
358  C C   . GLY A 84  ? 1.23425 1.13694 1.01731 0.22402  0.09264  0.15113  83  GLY A C   
359  O O   . GLY A 84  ? 1.31942 1.21250 1.10280 0.21897  0.10179  0.15923  83  GLY A O   
360  N N   . THR A 85  ? 1.19500 1.11077 0.99204 0.22122  0.08221  0.13675  84  THR A N   
361  C CA  . THR A 85  ? 1.20472 1.12426 1.01795 0.21256  0.08134  0.12969  84  THR A CA  
362  C C   . THR A 85  ? 1.09390 1.01679 0.92342 0.19065  0.09041  0.13378  84  THR A C   
363  O O   . THR A 85  ? 1.07435 1.00555 0.91164 0.17899  0.09154  0.13443  84  THR A O   
364  C CB  . THR A 85  ? 1.14620 1.08063 0.97182 0.21345  0.06836  0.11313  84  THR A CB  
365  O OG1 . THR A 85  ? 1.23790 1.17045 1.04823 0.23321  0.05912  0.10925  84  THR A OG1 
366  C CG2 . THR A 85  ? 1.08709 1.02385 0.92660 0.20860  0.06728  0.10568  84  THR A CG2 
367  N N   . ARG A 86  ? 1.06803 0.98406 0.90257 0.18516  0.09664  0.13648  85  ARG A N   
368  C CA  . ARG A 86  ? 0.97734 0.89500 0.82623 0.16462  0.10551  0.14065  85  ARG A CA  
369  C C   . ARG A 86  ? 0.96867 0.90224 0.83921 0.15081  0.09941  0.12709  85  ARG A C   
370  O O   . ARG A 86  ? 0.96008 0.89640 0.83735 0.15368  0.09452  0.11756  85  ARG A O   
371  C CB  . ARG A 86  ? 1.03355 0.93661 0.87826 0.16448  0.11465  0.14884  85  ARG A CB  
372  C CG  . ARG A 86  ? 0.95608 0.85983 0.81495 0.14327  0.12389  0.15320  85  ARG A CG  
373  N N   . VAL A 87  ? 0.87929 0.82340 0.76075 0.13602  0.09964  0.12618  86  VAL A N   
374  C CA  . VAL A 87  ? 0.72142 0.68099 0.62290 0.12165  0.09408  0.11390  86  VAL A CA  
375  C C   . VAL A 87  ? 0.75762 0.72035 0.67063 0.10028  0.10172  0.11956  86  VAL A C   
376  O O   . VAL A 87  ? 0.77578 0.73082 0.68150 0.09792  0.10968  0.13213  86  VAL A O   
377  C CB  . VAL A 87  ? 0.75976 0.73176 0.66290 0.12729  0.08241  0.10371  86  VAL A CB  
378  C CG1 . VAL A 87  ? 0.74051 0.70929 0.63145 0.14896  0.07424  0.09826  86  VAL A CG1 
379  C CG2 . VAL A 87  ? 0.67973 0.65288 0.57748 0.12497  0.08389  0.11083  86  VAL A CG2 
380  N N   . PRO A 88  ? 0.66058 0.63461 0.59170 0.08424  0.09958  0.11059  87  PRO A N   
381  C CA  . PRO A 88  ? 0.63709 0.61551 0.57925 0.06356  0.10524  0.11514  87  PRO A CA  
382  C C   . PRO A 88  ? 0.62492 0.60731 0.56349 0.06299  0.10352  0.11992  87  PRO A C   
383  O O   . PRO A 88  ? 0.58688 0.57482 0.52119 0.07339  0.09506  0.11410  87  PRO A O   
384  C CB  . PRO A 88  ? 0.61968 0.61144 0.58020 0.04991  0.10019  0.10187  87  PRO A CB  
385  C CG  . PRO A 88  ? 0.70891 0.69915 0.66845 0.06190  0.09619  0.09324  87  PRO A CG  
386  C CD  . PRO A 88  ? 0.61783 0.60132 0.56034 0.08390  0.09207  0.09596  87  PRO A CD  
387  N N   . MET A 89  ? 0.64945 0.62861 0.58973 0.05098  0.11169  0.13072  88  MET A N   
388  C CA  . MET A 89  ? 0.64815 0.63178 0.58761 0.04805  0.11070  0.13539  88  MET A CA  
389  C C   . MET A 89  ? 0.55723 0.55573 0.50837 0.04127  0.10070  0.12349  88  MET A C   
390  O O   . MET A 89  ? 0.54654 0.54906 0.49331 0.04803  0.09516  0.12229  88  MET A O   
391  C CB  . MET A 89  ? 0.74022 0.72057 0.68466 0.03233  0.12041  0.14694  88  MET A CB  
392  C CG  . MET A 89  ? 0.72511 0.71031 0.67054 0.02803  0.11991  0.15221  88  MET A CG  
393  S SD  . MET A 89  ? 0.77784 0.75503 0.70309 0.05018  0.12044  0.15969  88  MET A SD  
394  C CE  . MET A 89  ? 0.76631 0.72729 0.68077 0.05380  0.13351  0.17421  88  MET A CE  
395  N N   . GLU A 90  ? 0.58003 0.58653 0.54583 0.02792  0.09840  0.11442  89  GLU A N   
396  C CA  . GLU A 90  ? 0.49743 0.51803 0.47490 0.02041  0.08917  0.10288  89  GLU A CA  
397  C C   . GLU A 90  ? 0.49494 0.51915 0.46522 0.03791  0.07919  0.09457  89  GLU A C   
398  O O   . GLU A 90  ? 0.51747 0.54943 0.49010 0.03716  0.07243  0.09052  89  GLU A O   
399  C CB  . GLU A 90  ? 0.55696 0.58459 0.54940 0.00623  0.08858  0.09356  89  GLU A CB  
400  C CG  . GLU A 90  ? 0.46020 0.50245 0.46549 -0.00365 0.07984  0.08203  89  GLU A CG  
401  C CD  . GLU A 90  ? 0.52798 0.57733 0.54814 -0.01964 0.08049  0.07373  89  GLU A CD  
402  O OE1 . GLU A 90  ? 0.48933 0.53208 0.50992 -0.02281 0.08766  0.07654  89  GLU A OE1 
403  O OE2 . GLU A 90  ? 0.51106 0.57238 0.54235 -0.02939 0.07404  0.06439  89  GLU A OE2 
404  N N   . VAL A 91  ? 0.50871 0.52678 0.46967 0.05412  0.07795  0.09222  90  VAL A N   
405  C CA  . VAL A 91  ? 0.48509 0.50615 0.43844 0.07138  0.06810  0.08436  90  VAL A CA  
406  C C   . VAL A 91  ? 0.48842 0.50386 0.42699 0.08285  0.06811  0.09241  90  VAL A C   
407  O O   . VAL A 91  ? 0.50074 0.52254 0.43758 0.08883  0.05964  0.08634  90  VAL A O   
408  C CB  . VAL A 91  ? 0.49225 0.50765 0.43921 0.08593  0.06666  0.08034  90  VAL A CB  
409  C CG1 . VAL A 91  ? 0.53254 0.54873 0.46836 0.10546  0.05716  0.07472  90  VAL A CG1 
410  C CG2 . VAL A 91  ? 0.50573 0.52963 0.46916 0.07552  0.06459  0.06922  90  VAL A CG2 
411  N N   . VAL A 92  ? 0.50541 0.50880 0.43309 0.08608  0.07778  0.10602  91  VAL A N   
412  C CA  . VAL A 92  ? 0.48512 0.48288 0.39885 0.09608  0.07945  0.11468  91  VAL A CA  
413  C C   . VAL A 92  ? 0.52580 0.53310 0.44787 0.08595  0.07577  0.11296  91  VAL A C   
414  O O   . VAL A 92  ? 0.49609 0.50550 0.41090 0.09595  0.06965  0.11040  91  VAL A O   
415  C CB  . VAL A 92  ? 0.57117 0.55614 0.47604 0.09605  0.09187  0.12999  91  VAL A CB  
416  C CG1 . VAL A 92  ? 0.55007 0.53097 0.44295 0.10381  0.09440  0.13887  91  VAL A CG1 
417  C CG2 . VAL A 92  ? 0.61326 0.58701 0.50711 0.10864  0.09500  0.13230  91  VAL A CG2 
418  N N   . LEU A 93  ? 0.48115 0.49368 0.41807 0.06595  0.07952  0.11466  92  LEU A N   
419  C CA  . LEU A 93  ? 0.44520 0.46581 0.39047 0.05510  0.07666  0.11437  92  LEU A CA  
420  C C   . LEU A 93  ? 0.48789 0.52010 0.44072 0.05474  0.06462  0.10017  92  LEU A C   
421  O O   . LEU A 93  ? 0.48959 0.52564 0.44056 0.05794  0.05912  0.09832  92  LEU A O   
422  C CB  . LEU A 93  ? 0.46687 0.48983 0.42592 0.03352  0.08325  0.11961  92  LEU A CB  
423  C CG  . LEU A 93  ? 0.52165 0.53376 0.47539 0.03140  0.09535  0.13351  92  LEU A CG  
424  C CD1 . LEU A 93  ? 0.47787 0.49353 0.44637 0.00897  0.10039  0.13711  92  LEU A CD1 
425  C CD2 . LEU A 93  ? 0.49249 0.49810 0.43352 0.04218  0.09926  0.14396  92  LEU A CD2 
426  N N   . LEU A 94  ? 0.48700 0.52513 0.44919 0.05016  0.06057  0.08988  93  LEU A N   
427  C CA  . LEU A 94  ? 0.48849 0.53805 0.45843 0.04991  0.04916  0.07593  93  LEU A CA  
428  C C   . LEU A 94  ? 0.45880 0.50672 0.41530 0.07011  0.04165  0.07208  93  LEU A C   
429  O O   . LEU A 94  ? 0.45575 0.51057 0.41452 0.07053  0.03358  0.06579  93  LEU A O   
430  C CB  . LEU A 94  ? 0.42874 0.48403 0.40930 0.04468  0.04691  0.06583  93  LEU A CB  
431  C CG  . LEU A 94  ? 0.46861 0.53116 0.46648 0.02166  0.04975  0.06378  93  LEU A CG  
432  C CD1 . LEU A 94  ? 0.39791 0.46338 0.40374 0.01854  0.05019  0.05583  93  LEU A CD1 
433  C CD2 . LEU A 94  ? 0.42224 0.49627 0.43061 0.01106  0.04190  0.05651  93  LEU A CD2 
434  N N   . LYS A 95  ? 0.46798 0.50631 0.40987 0.08702  0.04397  0.07573  94  LYS A N   
435  C CA  . LYS A 95  ? 0.51518 0.55121 0.44273 0.10668  0.03680  0.07232  94  LYS A CA  
436  C C   . LYS A 95  ? 0.55361 0.58722 0.47309 0.10971  0.03744  0.07881  94  LYS A C   
437  O O   . LYS A 95  ? 0.48847 0.52587 0.40356 0.11812  0.02874  0.07222  94  LYS A O   
438  C CB  . LYS A 95  ? 0.54325 0.56791 0.45530 0.12367  0.04017  0.07685  94  LYS A CB  
439  C CG  . LYS A 95  ? 0.66672 0.68864 0.56301 0.14419  0.03240  0.07305  94  LYS A CG  
440  N N   . LYS A 96  ? 0.49687 0.52447 0.41500 0.10261  0.04760  0.09145  95  LYS A N   
441  C CA  . LYS A 96  ? 0.52157 0.54682 0.43269 0.10555  0.04917  0.09823  95  LYS A CA  
442  C C   . LYS A 96  ? 0.53748 0.57346 0.46138 0.09395  0.04217  0.09157  95  LYS A C   
443  O O   . LYS A 96  ? 0.51329 0.54944 0.43064 0.10121  0.03819  0.09113  95  LYS A O   
444  C CB  . LYS A 96  ? 0.49494 0.51214 0.40360 0.09970  0.06193  0.11326  95  LYS A CB  
445  C CG  . LYS A 96  ? 0.57551 0.57988 0.46675 0.11482  0.06902  0.12178  95  LYS A CG  
446  C CD  . LYS A 96  ? 0.60220 0.59907 0.49311 0.10714  0.08200  0.13621  95  LYS A CD  
447  C CE  . LYS A 96  ? 0.69007 0.68606 0.57772 0.10662  0.08610  0.14474  95  LYS A CE  
448  N NZ  . LYS A 96  ? 0.73334 0.72478 0.60303 0.12617  0.08310  0.14481  95  LYS A NZ  
449  N N   . VAL A 97  ? 0.46899 0.51356 0.41063 0.07598  0.04060  0.08635  96  VAL A N   
450  C CA  . VAL A 97  ? 0.48973 0.54378 0.44331 0.06419  0.03406  0.08060  96  VAL A CA  
451  C C   . VAL A 97  ? 0.53214 0.59538 0.49114 0.06653  0.02194  0.06540  96  VAL A C   
452  O O   . VAL A 97  ? 0.48242 0.55310 0.44996 0.05851  0.01534  0.05971  96  VAL A O   
453  C CB  . VAL A 97  ? 0.46778 0.52607 0.43747 0.04163  0.03919  0.08440  96  VAL A CB  
454  C CG1 . VAL A 97  ? 0.48630 0.53599 0.45127 0.03925  0.05079  0.09938  96  VAL A CG1 
455  C CG2 . VAL A 97  ? 0.43687 0.49968 0.41680 0.03267  0.03903  0.07753  96  VAL A CG2 
456  N N   . SER A 98  ? 0.45180 0.51471 0.40632 0.07735  0.01856  0.05872  97  SER A N   
457  C CA  . SER A 98  ? 0.48957 0.56247 0.45194 0.07767  0.00751  0.04398  97  SER A CA  
458  C C   . SER A 98  ? 0.62373 0.69646 0.57463 0.09483  -0.00187 0.03779  97  SER A C   
459  O O   . SER A 98  ? 0.64273 0.72322 0.59847 0.09779  -0.01165 0.02536  97  SER A O   
460  C CB  . SER A 98  ? 0.56039 0.63469 0.52689 0.07876  0.00817  0.03880  97  SER A CB  
461  O OG  . SER A 98  ? 0.44246 0.51935 0.42248 0.06006  0.01504  0.04154  97  SER A OG  
462  N N   . SER A 99  ? 0.59912 0.66349 0.53524 0.10586  0.00086  0.04586  98  SER A N   
463  C CA  . SER A 99  ? 0.68429 0.74799 0.60873 0.12150  -0.00785 0.04019  98  SER A CA  
464  C C   . SER A 99  ? 0.73112 0.80157 0.66425 0.11204  -0.01379 0.03581  98  SER A C   
465  O O   . SER A 99  ? 0.72133 0.78980 0.65737 0.10296  -0.00804 0.04413  98  SER A O   
466  C CB  . SER A 99  ? 0.72869 0.78004 0.63234 0.13809  -0.00192 0.05055  98  SER A CB  
467  N N   . GLY A 100 ? 0.72688 0.80525 0.66461 0.11397  -0.02544 0.02279  99  GLY A N   
468  C CA  . GLY A 100 ? 0.71066 0.79509 0.65650 0.10548  -0.03210 0.01760  99  GLY A CA  
469  C C   . GLY A 100 ? 0.72626 0.81971 0.69270 0.08301  -0.03182 0.01482  99  GLY A C   
470  O O   . GLY A 100 ? 0.71246 0.80803 0.68737 0.07356  -0.02648 0.01630  99  GLY A O   
471  N N   . PHE A 101 ? 0.69898 0.79737 0.67311 0.07426  -0.03775 0.01068  100 PHE A N   
472  C CA  . PHE A 101 ? 0.60096 0.70758 0.59371 0.05258  -0.03828 0.00804  100 PHE A CA  
473  C C   . PHE A 101 ? 0.57930 0.68147 0.57531 0.04050  -0.02836 0.02099  100 PHE A C   
474  O O   . PHE A 101 ? 0.52098 0.61584 0.50749 0.04721  -0.02454 0.02967  100 PHE A O   
475  C CB  . PHE A 101 ? 0.63254 0.74578 0.63219 0.04783  -0.04918 -0.00170 100 PHE A CB  
476  C CG  . PHE A 101 ? 0.75275 0.87189 0.75172 0.05740  -0.05985 -0.01535 100 PHE A CG  
477  C CD1 . PHE A 101 ? 0.75900 0.88781 0.77093 0.04891  -0.06324 -0.02471 100 PHE A CD1 
478  C CD2 . PHE A 101 ? 0.72366 0.83896 0.70924 0.07477  -0.06660 -0.01907 100 PHE A CD2 
479  C CE1 . PHE A 101 ? 0.79018 0.92521 0.80257 0.05769  -0.07335 -0.03743 100 PHE A CE1 
480  C CE2 . PHE A 101 ? 0.76447 0.88540 0.74963 0.08346  -0.07698 -0.03171 100 PHE A CE2 
481  C CZ  . PHE A 101 ? 0.84732 0.97840 0.84636 0.07494  -0.08047 -0.04088 100 PHE A CZ  
482  N N   . SER A 102 ? 0.54136 0.64835 0.55121 0.02236  -0.02441 0.02198  101 SER A N   
483  C CA  . SER A 102 ? 0.57370 0.67723 0.58792 0.00941  -0.01565 0.03386  101 SER A CA  
484  C C   . SER A 102 ? 0.49770 0.60870 0.52852 -0.01201 -0.01459 0.03109  101 SER A C   
485  O O   . SER A 102 ? 0.50047 0.61890 0.53871 -0.01573 -0.01938 0.02057  101 SER A O   
486  C CB  . SER A 102 ? 0.51507 0.60915 0.51835 0.01800  -0.00478 0.04571  101 SER A CB  
487  O OG  . SER A 102 ? 0.50696 0.60201 0.51276 0.01639  -0.00106 0.04377  101 SER A OG  
488  N N   . GLY A 103 ? 0.42163 0.53069 0.45813 -0.02601 -0.00809 0.04073  102 GLY A N   
489  C CA  . GLY A 103 ? 0.40600 0.52053 0.45634 -0.04657 -0.00542 0.04013  102 GLY A CA  
490  C C   . GLY A 103 ? 0.40087 0.51253 0.45037 -0.04781 0.00356  0.04435  102 GLY A C   
491  O O   . GLY A 103 ? 0.37553 0.48671 0.43182 -0.06288 0.01011  0.05084  102 GLY A O   
492  N N   . VAL A 104 ? 0.39440 0.50370 0.43543 -0.03214 0.00379  0.04083  103 VAL A N   
493  C CA  . VAL A 104 ? 0.37985 0.48601 0.41982 -0.03183 0.01155  0.04359  103 VAL A CA  
494  C C   . VAL A 104 ? 0.38690 0.49948 0.43015 -0.02669 0.00591  0.03067  103 VAL A C   
495  O O   . VAL A 104 ? 0.43153 0.54638 0.46991 -0.01347 -0.00221 0.02290  103 VAL A O   
496  C CB  . VAL A 104 ? 0.51309 0.60789 0.53785 -0.01602 0.01889  0.05429  103 VAL A CB  
497  C CG1 . VAL A 104 ? 0.52113 0.61186 0.54531 -0.01694 0.02706  0.05756  103 VAL A CG1 
498  C CG2 . VAL A 104 ? 0.48317 0.57247 0.50499 -0.01958 0.02408  0.06661  103 VAL A CG2 
499  N N   . ILE A 105 ? 0.39035 0.50618 0.44228 -0.03728 0.01001  0.02799  104 ILE A N   
500  C CA  . ILE A 105 ? 0.38315 0.50435 0.43794 -0.03075 0.00607  0.01668  104 ILE A CA  
501  C C   . ILE A 105 ? 0.47378 0.58643 0.51370 -0.00896 0.00769  0.01982  104 ILE A C   
502  O O   . ILE A 105 ? 0.41661 0.51991 0.44920 -0.00578 0.01665  0.03005  104 ILE A O   
503  C CB  . ILE A 105 ? 0.40079 0.52612 0.46713 -0.04598 0.01141  0.01401  104 ILE A CB  
504  C CG1 . ILE A 105 ? 0.36164 0.49700 0.44267 -0.06680 0.00798  0.00818  104 ILE A CG1 
505  C CG2 . ILE A 105 ? 0.33629 0.46518 0.40399 -0.03627 0.00908  0.00422  104 ILE A CG2 
506  C CD1 . ILE A 105 ? 0.39678 0.54272 0.48418 -0.06467 -0.00322 -0.00552 104 ILE A CD1 
507  N N   . ARG A 106 ? 0.41032 0.52594 0.44551 0.00589  -0.00113 0.01109  105 ARG A N   
508  C CA  . ARG A 106 ? 0.41922 0.52651 0.43840 0.02786  -0.00127 0.01384  105 ARG A CA  
509  C C   . ARG A 106 ? 0.38663 0.49349 0.40585 0.03520  0.00018  0.00940  105 ARG A C   
510  O O   . ARG A 106 ? 0.38018 0.49668 0.41182 0.02881  -0.00378 -0.00142 105 ARG A O   
511  C CB  . ARG A 106 ? 0.38675 0.49686 0.39976 0.04072  -0.01202 0.00674  105 ARG A CB  
512  C CG  . ARG A 106 ? 0.52817 0.63589 0.53791 0.03715  -0.01263 0.01277  105 ARG A CG  
513  C CD  . ARG A 106 ? 0.58255 0.69432 0.58877 0.04677  -0.02404 0.00397  105 ARG A CD  
514  N NE  . ARG A 106 ? 0.60898 0.71447 0.59901 0.06905  -0.02673 0.00349  105 ARG A NE  
515  C CZ  . ARG A 106 ? 0.77778 0.88618 0.76270 0.08099  -0.03709 -0.00542 105 ARG A CZ  
516  N NH1 . ARG A 106 ? 0.69256 0.81016 0.68773 0.07306  -0.04586 -0.01495 105 ARG A NH1 
517  N NH2 . ARG A 106 ? 0.77048 0.87206 0.73924 0.10121  -0.03882 -0.00469 105 ARG A NH2 
518  N N   . LEU A 107 ? 0.40024 0.49565 0.40544 0.04880  0.00606  0.01800  106 LEU A N   
519  C CA  . LEU A 107 ? 0.42453 0.51706 0.42645 0.05968  0.00700  0.01502  106 LEU A CA  
520  C C   . LEU A 107 ? 0.49462 0.58958 0.48927 0.07819  -0.00353 0.00612  106 LEU A C   
521  O O   . LEU A 107 ? 0.44865 0.53709 0.42844 0.09213  -0.00585 0.01039  106 LEU A O   
522  C CB  . LEU A 107 ? 0.45023 0.52855 0.43921 0.06663  0.01741  0.02848  106 LEU A CB  
523  C CG  . LEU A 107 ? 0.45834 0.53178 0.44305 0.07808  0.01900  0.02664  106 LEU A CG  
524  C CD1 . LEU A 107 ? 0.42221 0.50090 0.42274 0.06262  0.02337  0.02236  106 LEU A CD1 
525  C CD2 . LEU A 107 ? 0.46389 0.52186 0.43110 0.09009  0.02707  0.04001  106 LEU A CD2 
526  N N   . LEU A 108 ? 0.41970 0.52424 0.42488 0.07823  -0.00990 -0.00637 107 LEU A N   
527  C CA  . LEU A 108 ? 0.44401 0.55270 0.44476 0.09441  -0.02098 -0.01626 107 LEU A CA  
528  C C   . LEU A 108 ? 0.53739 0.63825 0.52718 0.11241  -0.02025 -0.01495 107 LEU A C   
529  O O   . LEU A 108 ? 0.48328 0.58167 0.46124 0.13022  -0.02755 -0.01771 107 LEU A O   
530  C CB  . LEU A 108 ? 0.47680 0.60132 0.49609 0.08477  -0.02900 -0.03115 107 LEU A CB  
531  C CG  . LEU A 108 ? 0.45900 0.59191 0.49044 0.06570  -0.03037 -0.03352 107 LEU A CG  
532  C CD1 . LEU A 108 ? 0.46814 0.61638 0.51739 0.05699  -0.03777 -0.04829 107 LEU A CD1 
533  C CD2 . LEU A 108 ? 0.53525 0.66481 0.55633 0.07148  -0.03516 -0.03029 107 LEU A CD2 
534  N N   . ASP A 109 ? 0.47510 0.57152 0.46819 0.10810  -0.01179 -0.01077 108 ASP A N   
535  C CA  . ASP A 109 ? 0.52501 0.61288 0.50836 0.12398  -0.01025 -0.00872 108 ASP A CA  
536  C C   . ASP A 109 ? 0.53688 0.61863 0.52475 0.11365  0.00150  -0.00146 108 ASP A C   
537  O O   . ASP A 109 ? 0.44362 0.52969 0.44329 0.09458  0.00690  -0.00015 108 ASP A O   
538  C CB  . ASP A 109 ? 0.55764 0.65513 0.54843 0.13278  -0.02042 -0.02282 108 ASP A CB  
539  C CG  . ASP A 109 ? 0.66864 0.75642 0.64498 0.15411  -0.02210 -0.02072 108 ASP A CG  
540  O OD1 . ASP A 109 ? 0.58818 0.66151 0.54704 0.16301  -0.01597 -0.00841 108 ASP A OD1 
541  O OD2 . ASP A 109 ? 0.68108 0.77590 0.66395 0.16169  -0.02960 -0.03140 108 ASP A OD2 
542  N N   . TRP A 110 ? 0.51969 0.59066 0.49737 0.12642  0.00530  0.00349  109 TRP A N   
543  C CA  . TRP A 110 ? 0.54662 0.61088 0.52805 0.11842  0.01589  0.00952  109 TRP A CA  
544  C C   . TRP A 110 ? 0.60591 0.66346 0.58119 0.13448  0.01493  0.00790  109 TRP A C   
545  O O   . TRP A 110 ? 0.62130 0.67603 0.58502 0.15290  0.00767  0.00595  109 TRP A O   
546  C CB  . TRP A 110 ? 0.47417 0.52615 0.44539 0.11320  0.02673  0.02522  109 TRP A CB  
547  C CG  . TRP A 110 ? 0.54389 0.58273 0.49364 0.13115  0.02774  0.03498  109 TRP A CG  
548  C CD1 . TRP A 110 ? 0.57142 0.60922 0.50996 0.13893  0.02361  0.03780  109 TRP A CD1 
549  C CD2 . TRP A 110 ? 0.56047 0.58476 0.49656 0.14371  0.03349  0.04339  109 TRP A CD2 
550  N NE1 . TRP A 110 ? 0.62781 0.65168 0.54630 0.15544  0.02668  0.04737  109 TRP A NE1 
551  C CE2 . TRP A 110 ? 0.62586 0.64106 0.54232 0.15861  0.03268  0.05120  109 TRP A CE2 
552  C CE3 . TRP A 110 ? 0.58546 0.60311 0.52373 0.14386  0.03927  0.04501  109 TRP A CE3 
553  C CZ2 . TRP A 110 ? 0.62793 0.62773 0.52664 0.17328  0.03750  0.06082  109 TRP A CZ2 
554  C CZ3 . TRP A 110 ? 0.69921 0.70115 0.62021 0.15854  0.04380  0.05461  109 TRP A CZ3 
555  C CH2 . TRP A 110 ? 0.71861 0.71183 0.61985 0.17303  0.04285  0.06252  109 TRP A CH2 
556  N N   . PHE A 111 ? 0.59145 0.64611 0.57440 0.12725  0.02219  0.00872  110 PHE A N   
557  C CA  . PHE A 111 ? 0.65125 0.69968 0.63111 0.14031  0.02201  0.00677  110 PHE A CA  
558  C C   . PHE A 111 ? 0.64496 0.68057 0.62206 0.13417  0.03448  0.01728  110 PHE A C   
559  O O   . PHE A 111 ? 0.52551 0.56296 0.51175 0.11566  0.04189  0.02024  110 PHE A O   
560  C CB  . PHE A 111 ? 0.65535 0.71794 0.65355 0.13771  0.01545  -0.00889 110 PHE A CB  
561  C CG  . PHE A 111 ? 0.73656 0.81366 0.74097 0.14086  0.00320  -0.02062 110 PHE A CG  
562  C CD1 . PHE A 111 ? 0.74217 0.83178 0.75908 0.12419  0.00144  -0.02578 110 PHE A CD1 
563  C CD2 . PHE A 111 ? 0.93630 1.01438 0.93417 0.16032  -0.00688 -0.02665 110 PHE A CD2 
564  C CE1 . PHE A 111 ? 0.81859 0.92116 0.84139 0.12670  -0.00988 -0.03664 110 PHE A CE1 
565  C CE2 . PHE A 111 ? 0.96112 1.05262 0.96503 0.16298  -0.01846 -0.03775 110 PHE A CE2 
566  C CZ  . PHE A 111 ? 0.88976 0.99346 0.90628 0.14604  -0.01984 -0.04280 110 PHE A CZ  
567  N N   . GLU A 112 ? 0.61653 0.63893 0.58103 0.14958  0.03651  0.02273  111 GLU A N   
568  C CA  . GLU A 112 ? 0.61420 0.62409 0.57685 0.14512  0.04755  0.03122  111 GLU A CA  
569  C C   . GLU A 112 ? 0.63128 0.64408 0.60539 0.14726  0.04610  0.02155  111 GLU A C   
570  O O   . GLU A 112 ? 0.65824 0.67408 0.63136 0.16245  0.03732  0.01371  111 GLU A O   
571  C CB  . GLU A 112 ? 0.68110 0.67248 0.62157 0.15957  0.05228  0.04526  111 GLU A CB  
572  C CG  . GLU A 112 ? 0.69517 0.67272 0.63330 0.15478  0.06380  0.05456  111 GLU A CG  
573  C CD  . GLU A 112 ? 0.76781 0.72735 0.68439 0.16602  0.06977  0.06973  111 GLU A CD  
574  O OE1 . GLU A 112 ? 0.87871 0.83648 0.78151 0.17808  0.06507  0.07296  111 GLU A OE1 
575  O OE2 . GLU A 112 ? 0.77133 0.71834 0.68462 0.16251  0.07938  0.07839  111 GLU A OE2 
576  N N   . ARG A 113 ? 0.61066 0.62280 0.59588 0.13197  0.05453  0.02185  112 ARG A N   
577  C CA  . ARG A 113 ? 0.71973 0.73300 0.71593 0.13243  0.05534  0.01380  112 ARG A CA  
578  C C   . ARG A 113 ? 0.66402 0.65911 0.65150 0.13295  0.06613  0.02516  112 ARG A C   
579  O O   . ARG A 113 ? 0.64698 0.63112 0.62237 0.13017  0.07300  0.03843  112 ARG A O   
580  C CB  . ARG A 113 ? 0.60632 0.63564 0.62442 0.11294  0.05574  0.00254  112 ARG A CB  
581  C CG  . ARG A 113 ? 0.60901 0.65667 0.63838 0.11461  0.04426  -0.01154 112 ARG A CG  
582  C CD  . ARG A 113 ? 0.65865 0.72102 0.70870 0.09428  0.04598  -0.02154 112 ARG A CD  
583  N NE  . ARG A 113 ? 0.68576 0.76560 0.74940 0.09658  0.03573  -0.03685 112 ARG A NE  
584  C CZ  . ARG A 113 ? 0.66284 0.75783 0.74464 0.08002  0.03541  -0.04709 112 ARG A CZ  
585  N NH1 . ARG A 113 ? 0.56826 0.66319 0.65621 0.05990  0.04420  -0.04380 112 ARG A NH1 
586  N NH2 . ARG A 113 ? 0.61877 0.72934 0.71270 0.08352  0.02601  -0.06091 112 ARG A NH2 
587  N N   . PRO A 114 ? 0.73638 0.72758 0.72966 0.13662  0.06796  0.02052  113 PRO A N   
588  C CA  . PRO A 114 ? 0.72690 0.69960 0.71140 0.13718  0.07822  0.03152  113 PRO A CA  
589  C C   . PRO A 114 ? 0.68001 0.64880 0.66650 0.11711  0.08909  0.04023  113 PRO A C   
590  O O   . PRO A 114 ? 0.69350 0.64685 0.66621 0.11880  0.09644  0.05398  113 PRO A O   
591  C CB  . PRO A 114 ? 0.76216 0.73625 0.75855 0.13995  0.07765  0.02136  113 PRO A CB  
592  C CG  . PRO A 114 ? 0.72281 0.71050 0.72533 0.15189  0.06519  0.00868  113 PRO A CG  
593  C CD  . PRO A 114 ? 0.65361 0.65587 0.66039 0.14273  0.06038  0.00553  113 PRO A CD  
594  N N   . ASP A 115 ? 0.63079 0.61328 0.63385 0.09804  0.09013  0.03276  114 ASP A N   
595  C CA  . ASP A 115 ? 0.62883 0.60830 0.63549 0.07781  0.10009  0.03984  114 ASP A CA  
596  C C   . ASP A 115 ? 0.64554 0.63617 0.65599 0.06456  0.09837  0.04079  114 ASP A C   
597  O O   . ASP A 115 ? 0.56909 0.55977 0.58461 0.04621  0.10545  0.04528  114 ASP A O   
598  C CB  . ASP A 115 ? 0.62813 0.61168 0.65068 0.06432  0.10471  0.03128  114 ASP A CB  
599  C CG  . ASP A 115 ? 0.77719 0.74899 0.79710 0.07630  0.10709  0.03031  114 ASP A CG  
600  O OD1 . ASP A 115 ? 0.73922 0.69338 0.74447 0.08473  0.11231  0.04234  114 ASP A OD1 
601  O OD2 . ASP A 115 ? 0.74369 0.72396 0.77643 0.07734  0.10373  0.01746  114 ASP A OD2 
602  N N   . SER A 116 ? 0.57602 0.54200 0.50236 0.17077  0.08327  0.07704  115 SER A N   
603  C CA  . SER A 116 ? 0.63979 0.62225 0.57657 0.15539  0.08015  0.07172  115 SER A CA  
604  C C   . SER A 116 ? 0.56916 0.57262 0.51011 0.15132  0.07815  0.07577  115 SER A C   
605  O O   . SER A 116 ? 0.57634 0.58607 0.51212 0.16149  0.07864  0.08210  115 SER A O   
606  C CB  . SER A 116 ? 0.60796 0.61025 0.54900 0.15660  0.07808  0.06496  115 SER A CB  
607  O OG  . SER A 116 ? 0.61444 0.64202 0.55586 0.16840  0.07734  0.06779  115 SER A OG  
608  N N   . PHE A 117 ? 0.56210 0.57507 0.51131 0.13695  0.07549  0.07165  116 PHE A N   
609  C CA  . PHE A 117 ? 0.58047 0.61568 0.53457 0.13159  0.07193  0.07241  116 PHE A CA  
610  C C   . PHE A 117 ? 0.48689 0.54609 0.45026 0.12544  0.06786  0.06625  116 PHE A C   
611  O O   . PHE A 117 ? 0.47433 0.52878 0.44076 0.11987  0.06837  0.06130  116 PHE A O   
612  C CB  . PHE A 117 ? 0.56852 0.59230 0.52397 0.11995  0.07259  0.07341  116 PHE A CB  
613  C CG  . PHE A 117 ? 0.59230 0.59838 0.53996 0.12560  0.07706  0.08166  116 PHE A CG  
614  C CD1 . PHE A 117 ? 0.59082 0.56898 0.53555 0.12602  0.08177  0.08423  116 PHE A CD1 
615  C CD2 . PHE A 117 ? 0.58648 0.60353 0.52948 0.13079  0.07646  0.08703  116 PHE A CD2 
616  C CE1 . PHE A 117 ? 0.62548 0.58687 0.56395 0.13071  0.08679  0.09337  116 PHE A CE1 
617  C CE2 . PHE A 117 ? 0.68200 0.68319 0.61686 0.13679  0.08163  0.09601  116 PHE A CE2 
618  C CZ  . PHE A 117 ? 0.65824 0.63156 0.59145 0.13637  0.08729  0.09982  116 PHE A CZ  
619  N N   . VAL A 118 ? 0.49600 0.58080 0.46380 0.12659  0.06368  0.06675  117 VAL A N   
620  C CA  . VAL A 118 ? 0.51101 0.62051 0.48955 0.12021  0.05979  0.06229  117 VAL A CA  
621  C C   . VAL A 118 ? 0.53612 0.65449 0.51953 0.10880  0.05491  0.06044  117 VAL A C   
622  O O   . VAL A 118 ? 0.51047 0.63311 0.49005 0.11247  0.05241  0.06299  117 VAL A O   
623  C CB  . VAL A 118 ? 0.49473 0.62943 0.47690 0.13153  0.05811  0.06391  117 VAL A CB  
624  C CG1 . VAL A 118 ? 0.49174 0.64987 0.48664 0.12425  0.05591  0.06030  117 VAL A CG1 
625  C CG2 . VAL A 118 ? 0.55452 0.67745 0.52801 0.14696  0.06297  0.06680  117 VAL A CG2 
626  N N   . LEU A 119 ? 0.46029 0.58086 0.45076 0.09614  0.05340  0.05595  118 LEU A N   
627  C CA  . LEU A 119 ? 0.45855 0.58305 0.45266 0.08484  0.04884  0.05336  118 LEU A CA  
628  C C   . LEU A 119 ? 0.47572 0.62453 0.48139 0.07852  0.04397  0.05049  118 LEU A C   
629  O O   . LEU A 119 ? 0.43194 0.58622 0.44352 0.07559  0.04596  0.04936  118 LEU A O   
630  C CB  . LEU A 119 ? 0.39231 0.49684 0.38504 0.07475  0.05097  0.05090  118 LEU A CB  
631  C CG  . LEU A 119 ? 0.48802 0.56986 0.47288 0.07589  0.05462  0.05354  118 LEU A CG  
632  C CD1 . LEU A 119 ? 0.53062 0.60012 0.50887 0.08726  0.05947  0.05798  118 LEU A CD1 
633  C CD2 . LEU A 119 ? 0.49749 0.56445 0.48425 0.06551  0.05588  0.05020  118 LEU A CD2 
634  N N   . ILE A 120 ? 0.42143 0.58465 0.43029 0.07653  0.03757  0.04944  119 ILE A N   
635  C CA  . ILE A 120 ? 0.41478 0.60025 0.43654 0.06846  0.03189  0.04665  119 ILE A CA  
636  C C   . ILE A 120 ? 0.38152 0.55850 0.40474 0.05498  0.02849  0.04267  119 ILE A C   
637  O O   . ILE A 120 ? 0.37428 0.54457 0.39127 0.05416  0.02476  0.04095  119 ILE A O   
638  C CB  . ILE A 120 ? 0.48752 0.69526 0.51323 0.07436  0.02518  0.04672  119 ILE A CB  
639  C CG1 . ILE A 120 ? 0.47957 0.69341 0.50091 0.09030  0.02848  0.05117  119 ILE A CG1 
640  C CG2 . ILE A 120 ? 0.46946 0.70128 0.51206 0.06479  0.01971  0.04430  119 ILE A CG2 
641  C CD1 . ILE A 120 ? 0.45399 0.67768 0.48263 0.09358  0.03353  0.05304  119 ILE A CD1 
642  N N   . LEU A 121 ? 0.38596 0.56377 0.41657 0.04548  0.02980  0.04143  120 LEU A N   
643  C CA  . LEU A 121 ? 0.32310 0.49047 0.35419 0.03348  0.02731  0.03810  120 LEU A CA  
644  C C   . LEU A 121 ? 0.40750 0.59185 0.45177 0.02333  0.02203  0.03657  120 LEU A C   
645  O O   . LEU A 121 ? 0.38957 0.59370 0.44445 0.02407  0.02251  0.03885  120 LEU A O   
646  C CB  . LEU A 121 ? 0.45521 0.60480 0.48205 0.03055  0.03342  0.03826  120 LEU A CB  
647  C CG  . LEU A 121 ? 0.47200 0.60485 0.48856 0.03949  0.03875  0.03997  120 LEU A CG  
648  C CD1 . LEU A 121 ? 0.46607 0.58917 0.48114 0.03965  0.04422  0.03996  120 LEU A CD1 
649  C CD2 . LEU A 121 ? 0.42847 0.54561 0.43784 0.03733  0.03768  0.03876  120 LEU A CD2 
650  N N   . GLU A 122 ? 0.35704 0.53331 0.40103 0.01383  0.01717  0.03297  121 GLU A N   
651  C CA  . GLU A 122 ? 0.41516 0.60141 0.47139 0.00201  0.01294  0.03193  121 GLU A CA  
652  C C   . GLU A 122 ? 0.40564 0.59419 0.46750 -0.00146 0.01980  0.03580  121 GLU A C   
653  O O   . GLU A 122 ? 0.41362 0.58827 0.46702 0.00237  0.02622  0.03691  121 GLU A O   
654  C CB  . GLU A 122 ? 0.47438 0.64490 0.52624 -0.00666 0.00792  0.02751  121 GLU A CB  
655  C CG  . GLU A 122 ? 0.45274 0.61838 0.49607 -0.00254 0.00150  0.02313  121 GLU A CG  
656  C CD  . GLU A 122 ? 0.63838 0.78803 0.67683 -0.01025 -0.00310 0.01848  121 GLU A CD  
657  O OE1 . GLU A 122 ? 0.48137 0.61479 0.51416 -0.01236 0.00184  0.01923  121 GLU A OE1 
658  O OE2 . GLU A 122 ? 0.61720 0.77071 0.65751 -0.01380 -0.01217 0.01368  121 GLU A OE2 
659  N N   . ARG A 123 ? 0.38376 0.59024 0.46021 -0.00895 0.01826  0.03789  122 ARG A N   
660  C CA  . ARG A 123 ? 0.40594 0.61539 0.48749 -0.01309 0.02492  0.04231  122 ARG A CA  
661  C C   . ARG A 123 ? 0.40232 0.61477 0.49487 -0.02753 0.02077  0.04278  122 ARG A C   
662  O O   . ARG A 123 ? 0.38798 0.62197 0.49674 -0.03310 0.01824  0.04522  122 ARG A O   
663  C CB  . ARG A 123 ? 0.39296 0.62455 0.48230 -0.00544 0.03039  0.04711  122 ARG A CB  
664  C CG  . ARG A 123 ? 0.45143 0.68899 0.54588 -0.00892 0.03774  0.05234  122 ARG A CG  
665  C CD  . ARG A 123 ? 0.41312 0.66749 0.50942 0.00273  0.04484  0.05638  122 ARG A CD  
666  N NE  . ARG A 123 ? 0.49964 0.78159 0.61015 0.00550  0.04185  0.05814  122 ARG A NE  
667  C CZ  . ARG A 123 ? 0.49356 0.80160 0.62301 -0.00128 0.04212  0.06283  122 ARG A CZ  
668  N NH1 . ARG A 123 ? 0.47184 0.78093 0.60796 -0.01171 0.04568  0.06702  122 ARG A NH1 
669  N NH2 . ARG A 123 ? 0.47633 0.81068 0.61894 0.00253  0.03876  0.06381  122 ARG A NH2 
670  N N   . PRO A 124 ? 0.41156 0.60285 0.49651 -0.03399 0.01975  0.04069  123 PRO A N   
671  C CA  . PRO A 124 ? 0.45932 0.65046 0.55376 -0.04742 0.01714  0.04240  123 PRO A CA  
672  C C   . PRO A 124 ? 0.47992 0.68411 0.58317 -0.04988 0.02521  0.05018  123 PRO A C   
673  O O   . PRO A 124 ? 0.40091 0.60691 0.49792 -0.04086 0.03308  0.05296  123 PRO A O   
674  C CB  . PRO A 124 ? 0.43840 0.60222 0.51923 -0.05005 0.01581  0.03884  123 PRO A CB  
675  C CG  . PRO A 124 ? 0.49784 0.65021 0.56405 -0.03849 0.01970  0.03657  123 PRO A CG  
676  C CD  . PRO A 124 ? 0.39701 0.56444 0.46565 -0.02966 0.01958  0.03643  123 PRO A CD  
677  N N   . GLU A 125 ? 0.40044 0.61336 0.51808 -0.06204 0.02321  0.05380  124 GLU A N   
678  C CA  . GLU A 125 ? 0.47456 0.70246 0.60215 -0.06505 0.03149  0.06266  124 GLU A CA  
679  C C   . GLU A 125 ? 0.49817 0.72053 0.63514 -0.08043 0.02921  0.06625  124 GLU A C   
680  O O   . GLU A 125 ? 0.41224 0.63496 0.55904 -0.09003 0.01997  0.06277  124 GLU A O   
681  C CB  . GLU A 125 ? 0.46537 0.72539 0.60907 -0.06142 0.03323  0.06632  124 GLU A CB  
682  C CG  . GLU A 125 ? 0.65545 0.92989 0.79961 -0.05356 0.04493  0.07390  124 GLU A CG  
683  C CD  . GLU A 125 ? 0.64234 0.90357 0.76630 -0.03802 0.04985  0.07061  124 GLU A CD  
684  O OE1 . GLU A 125 ? 0.57619 0.84021 0.69623 -0.02851 0.04720  0.06621  124 GLU A OE1 
685  O OE2 . GLU A 125 ? 0.76106 1.00893 0.87313 -0.03527 0.05616  0.07258  124 GLU A OE2 
686  N N   . PRO A 126 ? 0.46931 0.68449 0.60231 -0.08280 0.03694  0.07295  125 PRO A N   
687  C CA  . PRO A 126 ? 0.41879 0.63029 0.53797 -0.07179 0.04678  0.07611  125 PRO A CA  
688  C C   . PRO A 126 ? 0.45849 0.64165 0.55637 -0.06574 0.04489  0.06927  125 PRO A C   
689  O O   . PRO A 126 ? 0.44519 0.61001 0.53892 -0.07195 0.03816  0.06485  125 PRO A O   
690  C CB  . PRO A 126 ? 0.40762 0.62397 0.53348 -0.07936 0.05395  0.08647  125 PRO A CB  
691  C CG  . PRO A 126 ? 0.50548 0.70818 0.63801 -0.09417 0.04641  0.08584  125 PRO A CG  
692  C CD  . PRO A 126 ? 0.49469 0.70392 0.63701 -0.09754 0.03572  0.07812  125 PRO A CD  
693  N N   . VAL A 127 ? 0.39621 0.57580 0.48097 -0.05354 0.05060  0.06820  126 VAL A N   
694  C CA  . VAL A 127 ? 0.38768 0.54378 0.45467 -0.04733 0.04887  0.06161  126 VAL A CA  
695  C C   . VAL A 127 ? 0.47520 0.62584 0.53027 -0.04012 0.05638  0.06432  126 VAL A C   
696  O O   . VAL A 127 ? 0.40012 0.56650 0.45776 -0.03504 0.06338  0.06958  126 VAL A O   
697  C CB  . VAL A 127 ? 0.50227 0.65826 0.56537 -0.03872 0.04574  0.05505  126 VAL A CB  
698  C CG1 . VAL A 127 ? 0.53106 0.67230 0.57863 -0.02866 0.04870  0.05129  126 VAL A CG1 
699  C CG2 . VAL A 127 ? 0.39750 0.54511 0.46196 -0.04395 0.03695  0.04953  126 VAL A CG2 
700  N N   . GLN A 128 ? 0.42685 0.55593 0.46853 -0.03903 0.05465  0.06051  127 GLN A N   
701  C CA  . GLN A 128 ? 0.40207 0.52339 0.42980 -0.03004 0.05938  0.05986  127 GLN A CA  
702  C C   . GLN A 128 ? 0.43676 0.53846 0.45380 -0.02662 0.05443  0.05159  127 GLN A C   
703  O O   . GLN A 128 ? 0.42674 0.51749 0.44431 -0.03272 0.04884  0.04880  127 GLN A O   
704  C CB  . GLN A 128 ? 0.43776 0.55560 0.46110 -0.03316 0.06352  0.06634  127 GLN A CB  
705  C CG  . GLN A 128 ? 0.38428 0.49511 0.39177 -0.02274 0.06761  0.06504  127 GLN A CG  
706  C CD  . GLN A 128 ? 0.46667 0.57449 0.46820 -0.02461 0.07193  0.07226  127 GLN A CD  
707  O OE1 . GLN A 128 ? 0.47331 0.57144 0.47664 -0.03334 0.06916  0.07485  127 GLN A OE1 
708  N NE2 . GLN A 128 ? 0.50280 0.61816 0.49608 -0.01557 0.07884  0.07575  127 GLN A NE2 
709  N N   . ASP A 129 ? 0.40126 0.49869 0.40921 -0.01688 0.05631  0.04758  128 ASP A N   
710  C CA  . ASP A 129 ? 0.44868 0.52894 0.44941 -0.01519 0.05169  0.04050  128 ASP A CA  
711  C C   . ASP A 129 ? 0.44061 0.50750 0.43239 -0.01674 0.05048  0.03986  128 ASP A C   
712  O O   . ASP A 129 ? 0.41787 0.48727 0.40552 -0.01618 0.05414  0.04447  128 ASP A O   
713  C CB  . ASP A 129 ? 0.40544 0.48308 0.40119 -0.00577 0.05276  0.03578  128 ASP A CB  
714  C CG  . ASP A 129 ? 0.52830 0.60280 0.51353 0.00216  0.05614  0.03460  128 ASP A CG  
715  O OD1 . ASP A 129 ? 0.54216 0.60761 0.51954 0.00178  0.05518  0.03357  128 ASP A OD1 
716  O OD2 . ASP A 129 ? 0.61132 0.69169 0.59485 0.01012  0.05931  0.03403  128 ASP A OD2 
717  N N   . LEU A 130 ? 0.41259 0.46614 0.40141 -0.01821 0.04552  0.03469  129 LEU A N   
718  C CA  . LEU A 130 ? 0.40662 0.44823 0.38800 -0.01973 0.04338  0.03405  129 LEU A CA  
719  C C   . LEU A 130 ? 0.41906 0.45672 0.38978 -0.01224 0.04513  0.03210  129 LEU A C   
720  O O   . LEU A 130 ? 0.40760 0.43987 0.37096 -0.01201 0.04516  0.03412  129 LEU A O   
721  C CB  . LEU A 130 ? 0.36509 0.39584 0.34674 -0.02195 0.03788  0.02892  129 LEU A CB  
722  C CG  . LEU A 130 ? 0.40670 0.42544 0.38105 -0.02249 0.03494  0.02773  129 LEU A CG  
723  C CD1 . LEU A 130 ? 0.35739 0.37408 0.33114 -0.02806 0.03536  0.03370  129 LEU A CD1 
724  C CD2 . LEU A 130 ? 0.37238 0.38339 0.34792 -0.02306 0.03032  0.02261  129 LEU A CD2 
725  N N   . PHE A 131 ? 0.41234 0.45149 0.38103 -0.00549 0.04614  0.02798  130 PHE A N   
726  C CA  . PHE A 131 ? 0.41221 0.44772 0.36977 0.00230  0.04704  0.02522  130 PHE A CA  
727  C C   . PHE A 131 ? 0.44608 0.49043 0.39853 0.00482  0.05270  0.03216  130 PHE A C   
728  O O   . PHE A 131 ? 0.41965 0.45936 0.36201 0.00759  0.05281  0.03316  130 PHE A O   
729  C CB  . PHE A 131 ? 0.42036 0.45454 0.37670 0.00909  0.04696  0.01947  130 PHE A CB  
730  C CG  . PHE A 131 ? 0.44341 0.47222 0.38737 0.01758  0.04637  0.01479  130 PHE A CG  
731  C CD1 . PHE A 131 ? 0.47168 0.50841 0.40787 0.02483  0.05149  0.01788  130 PHE A CD1 
732  C CD2 . PHE A 131 ? 0.44618 0.46320 0.38623 0.01869  0.04049  0.00730  130 PHE A CD2 
733  C CE1 . PHE A 131 ? 0.52227 0.55361 0.44466 0.03396  0.05038  0.01287  130 PHE A CE1 
734  C CE2 . PHE A 131 ? 0.46193 0.47384 0.39002 0.02671  0.03848  0.00181  130 PHE A CE2 
735  C CZ  . PHE A 131 ? 0.54970 0.56799 0.46775 0.03483  0.04324  0.00425  130 PHE A CZ  
736  N N   . ASP A 132 ? 0.44848 0.50689 0.40805 0.00432  0.05774  0.03763  131 ASP A N   
737  C CA  . ASP A 132 ? 0.44066 0.51046 0.39751 0.00653  0.06445  0.04565  131 ASP A CA  
738  C C   . ASP A 132 ? 0.38750 0.45497 0.34582 -0.00162 0.06490  0.05266  131 ASP A C   
739  O O   . ASP A 132 ? 0.49906 0.56850 0.44946 0.00125  0.06940  0.05854  131 ASP A O   
740  C CB  . ASP A 132 ? 0.45743 0.54535 0.42499 0.00678  0.06941  0.05035  131 ASP A CB  
741  C CG  . ASP A 132 ? 0.53653 0.62678 0.49957 0.01751  0.07061  0.04497  131 ASP A CG  
742  O OD1 . ASP A 132 ? 0.54439 0.62409 0.49428 0.02563  0.06915  0.03890  131 ASP A OD1 
743  O OD2 . ASP A 132 ? 0.58323 0.68543 0.55569 0.01813  0.07250  0.04655  131 ASP A OD2 
744  N N   . PHE A 133 ? 0.43441 0.49721 0.40212 -0.01125 0.06051  0.05250  132 PHE A N   
745  C CA  . PHE A 133 ? 0.44047 0.49755 0.40950 -0.01931 0.05996  0.05842  132 PHE A CA  
746  C C   . PHE A 133 ? 0.45263 0.49553 0.40695 -0.01490 0.05819  0.05701  132 PHE A C   
747  O O   . PHE A 133 ? 0.43768 0.47897 0.38653 -0.01560 0.06173  0.06451  132 PHE A O   
748  C CB  . PHE A 133 ? 0.41127 0.46321 0.39048 -0.02826 0.05397  0.05564  132 PHE A CB  
749  C CG  . PHE A 133 ? 0.46888 0.51311 0.45066 -0.03728 0.05243  0.06096  132 PHE A CG  
750  C CD1 . PHE A 133 ? 0.42915 0.48349 0.42265 -0.04562 0.05534  0.06886  132 PHE A CD1 
751  C CD2 . PHE A 133 ? 0.48584 0.51252 0.45924 -0.03753 0.04767  0.05791  132 PHE A CD2 
752  C CE1 . PHE A 133 ? 0.46592 0.51055 0.46233 -0.05474 0.05331  0.07349  132 PHE A CE1 
753  C CE2 . PHE A 133 ? 0.44197 0.45866 0.41656 -0.04519 0.04592  0.06261  132 PHE A CE2 
754  C CZ  . PHE A 133 ? 0.50507 0.52942 0.49096 -0.05414 0.04858  0.07025  132 PHE A CZ  
755  N N   . ILE A 134 ? 0.45272 0.48592 0.40093 -0.01012 0.05279  0.04787  133 ILE A N   
756  C CA  . ILE A 134 ? 0.44384 0.46523 0.37905 -0.00525 0.04976  0.04528  133 ILE A CA  
757  C C   . ILE A 134 ? 0.47471 0.50006 0.39686 0.00459  0.05393  0.04685  133 ILE A C   
758  O O   . ILE A 134 ? 0.50684 0.52665 0.41747 0.00808  0.05458  0.05036  133 ILE A O   
759  C CB  . ILE A 134 ? 0.42756 0.44054 0.36311 -0.00363 0.04271  0.03508  133 ILE A CB  
760  C CG1 . ILE A 134 ? 0.41715 0.42455 0.36159 -0.01171 0.03881  0.03449  133 ILE A CG1 
761  C CG2 . ILE A 134 ? 0.44483 0.44954 0.36755 0.00339  0.03910  0.03095  133 ILE A CG2 
762  C CD1 . ILE A 134 ? 0.41436 0.41695 0.36197 -0.01066 0.03347  0.02603  133 ILE A CD1 
763  N N   . THR A 135 ? 0.47807 0.51225 0.40013 0.01050  0.05664  0.04405  134 THR A N   
764  C CA  . THR A 135 ? 0.49091 0.52983 0.39934 0.02108  0.06113  0.04563  134 THR A CA  
765  C C   . THR A 135 ? 0.49512 0.54172 0.40153 0.01957  0.06901  0.05837  134 THR A C   
766  O O   . THR A 135 ? 0.47989 0.52379 0.37165 0.02645  0.07120  0.06168  134 THR A O   
767  C CB  . THR A 135 ? 0.49295 0.54048 0.40269 0.02758  0.06352  0.04152  134 THR A CB  
768  O OG1 . THR A 135 ? 0.48410 0.52221 0.39493 0.02898  0.05638  0.03029  134 THR A OG1 
769  C CG2 . THR A 135 ? 0.59059 0.64375 0.48459 0.04008  0.06869  0.04319  134 THR A CG2 
770  N N   . GLU A 136 ? 0.51099 0.56729 0.43235 0.01038  0.07315  0.06599  135 GLU A N   
771  C CA  . GLU A 136 ? 0.53938 0.60519 0.46184 0.00794  0.08160  0.07919  135 GLU A CA  
772  C C   . GLU A 136 ? 0.55274 0.60554 0.47156 0.00182  0.08022  0.08510  135 GLU A C   
773  O O   . GLU A 136 ? 0.57720 0.63124 0.48749 0.00452  0.08646  0.09481  135 GLU A O   
774  C CB  . GLU A 136 ? 0.57242 0.65446 0.51439 -0.00065 0.08573  0.08517  135 GLU A CB  
775  C CG  . GLU A 136 ? 0.64326 0.74060 0.58829 0.00689  0.08897  0.08197  135 GLU A CG  
776  C CD  . GLU A 136 ? 0.79682 0.91311 0.76193 -0.00108 0.09300  0.08874  135 GLU A CD  
777  O OE1 . GLU A 136 ? 0.72462 0.84064 0.70227 -0.01378 0.09192  0.09452  135 GLU A OE1 
778  O OE2 . GLU A 136 ? 0.86261 0.99386 0.83099 0.00569  0.09667  0.08785  135 GLU A OE2 
779  N N   . ARG A 137 ? 0.48879 0.52859 0.41296 -0.00553 0.07251  0.07988  136 ARG A N   
780  C CA  . ARG A 137 ? 0.55023 0.57632 0.47155 -0.01134 0.07093  0.08547  136 ARG A CA  
781  C C   . ARG A 137 ? 0.56899 0.58008 0.47372 -0.00335 0.06547  0.07976  136 ARG A C   
782  O O   . ARG A 137 ? 0.57797 0.57770 0.47557 -0.00449 0.06547  0.08572  136 ARG A O   
783  C CB  . ARG A 137 ? 0.62991 0.65091 0.56681 -0.02397 0.06597  0.08411  136 ARG A CB  
784  C CG  . ARG A 137 ? 0.70837 0.74488 0.66181 -0.03280 0.07152  0.09226  136 ARG A CG  
785  C CD  . ARG A 137 ? 0.73966 0.77278 0.70856 -0.04523 0.06624  0.09093  136 ARG A CD  
786  N NE  . ARG A 137 ? 0.75052 0.76441 0.71636 -0.05149 0.06232  0.09338  136 ARG A NE  
787  C CZ  . ARG A 137 ? 0.72191 0.73169 0.70014 -0.06363 0.05980  0.09670  136 ARG A CZ  
788  N NH1 . ARG A 137 ? 0.65702 0.68292 0.65268 -0.07149 0.06116  0.09909  136 ARG A NH1 
789  N NH2 . ARG A 137 ? 0.65747 0.64632 0.63046 -0.06758 0.05522  0.09719  136 ARG A NH2 
790  N N   . GLY A 138 ? 0.57333 0.58435 0.47181 0.00501  0.06086  0.06883  137 GLY A N   
791  C CA  . GLY A 138 ? 0.55367 0.55265 0.43945 0.01178  0.05430  0.06230  137 GLY A CA  
792  C C   . GLY A 138 ? 0.55686 0.54536 0.45059 0.00517  0.04689  0.05674  137 GLY A C   
793  O O   . GLY A 138 ? 0.51574 0.50622 0.42360 -0.00345 0.04610  0.05588  137 GLY A O   
794  N N   . ALA A 139 ? 0.52229 0.50039 0.40612 0.01033  0.04129  0.05286  138 ALA A N   
795  C CA  . ALA A 139 ? 0.52424 0.49278 0.41383 0.00602  0.03468  0.04805  138 ALA A CA  
796  C C   . ALA A 139 ? 0.45859 0.42089 0.35580 -0.00401 0.03665  0.05547  138 ALA A C   
797  O O   . ALA A 139 ? 0.43367 0.39221 0.32625 -0.00595 0.04145  0.06561  138 ALA A O   
798  C CB  . ALA A 139 ? 0.51038 0.46995 0.38687 0.01422  0.02943  0.04528  138 ALA A CB  
799  N N   . LEU A 140 ? 0.46396 0.42495 0.37287 -0.01044 0.03294  0.05057  139 LEU A N   
800  C CA  . LEU A 140 ? 0.46137 0.41578 0.37778 -0.02004 0.03313  0.05553  139 LEU A CA  
801  C C   . LEU A 140 ? 0.44136 0.37821 0.35012 -0.01921 0.02879  0.05628  139 LEU A C   
802  O O   . LEU A 140 ? 0.46565 0.39801 0.36917 -0.01274 0.02370  0.04954  139 LEU A O   
803  C CB  . LEU A 140 ? 0.45013 0.41023 0.38002 -0.02567 0.03047  0.04947  139 LEU A CB  
804  C CG  . LEU A 140 ? 0.40274 0.37893 0.33979 -0.02491 0.03376  0.04732  139 LEU A CG  
805  C CD1 . LEU A 140 ? 0.43158 0.41230 0.38046 -0.02958 0.03101  0.04210  139 LEU A CD1 
806  C CD2 . LEU A 140 ? 0.48953 0.47509 0.42822 -0.02730 0.04101  0.05656  139 LEU A CD2 
807  N N   . GLN A 141 ? 0.45375 0.38073 0.36299 -0.02600 0.03063  0.06452  140 GLN A N   
808  C CA  . GLN A 141 ? 0.46192 0.36967 0.36564 -0.02653 0.02582  0.06454  140 GLN A CA  
809  C C   . GLN A 141 ? 0.50572 0.41190 0.41441 -0.02581 0.01916  0.05389  140 GLN A C   
810  O O   . GLN A 141 ? 0.44440 0.36100 0.36428 -0.03021 0.01874  0.04945  140 GLN A O   
811  C CB  . GLN A 141 ? 0.47490 0.37241 0.38376 -0.03727 0.02762  0.07304  140 GLN A CB  
812  C CG  . GLN A 141 ? 0.66334 0.55995 0.56763 -0.03893 0.03507  0.08604  140 GLN A CG  
813  C CD  . GLN A 141 ? 0.75680 0.64342 0.67011 -0.05188 0.03623  0.09420  140 GLN A CD  
814  O OE1 . GLN A 141 ? 0.73152 0.60336 0.64771 -0.05688 0.02981  0.08995  140 GLN A OE1 
815  N NE2 . GLN A 141 ? 0.89822 0.79329 0.81650 -0.05729 0.04426  0.10572  140 GLN A NE2 
816  N N   . GLU A 142 ? 0.47082 0.36427 0.37078 -0.01956 0.01426  0.05042  141 GLU A N   
817  C CA  . GLU A 142 ? 0.46479 0.35891 0.36886 -0.01720 0.00889  0.04083  141 GLU A CA  
818  C C   . GLU A 142 ? 0.46777 0.35687 0.37999 -0.02561 0.00670  0.03921  141 GLU A C   
819  O O   . GLU A 142 ? 0.44468 0.34203 0.36406 -0.02582 0.00473  0.03247  141 GLU A O   
820  C CB  . GLU A 142 ? 0.48174 0.36464 0.37508 -0.00786 0.00437  0.03793  141 GLU A CB  
821  C CG  . GLU A 142 ? 0.52893 0.42007 0.41550 0.00135  0.00477  0.03716  141 GLU A CG  
822  C CD  . GLU A 142 ? 0.53212 0.41892 0.41188 0.01150  -0.00055 0.03217  141 GLU A CD  
823  O OE1 . GLU A 142 ? 0.51512 0.39521 0.39628 0.01259  -0.00410 0.02809  141 GLU A OE1 
824  O OE2 . GLU A 142 ? 0.54170 0.43323 0.41459 0.01924  -0.00140 0.03193  141 GLU A OE2 
825  N N   . GLU A 143 ? 0.46666 0.34199 0.37783 -0.03254 0.00673  0.04534  142 GLU A N   
826  C CA  . GLU A 143 ? 0.49327 0.36408 0.41275 -0.04120 0.00341  0.04295  142 GLU A CA  
827  C C   . GLU A 143 ? 0.46514 0.35617 0.39798 -0.04665 0.00580  0.04135  142 GLU A C   
828  O O   . GLU A 143 ? 0.44788 0.34212 0.38659 -0.04860 0.00208  0.03501  142 GLU A O   
829  C CB  . GLU A 143 ? 0.54434 0.39831 0.46316 -0.04977 0.00341  0.05084  142 GLU A CB  
830  C CG  . GLU A 143 ? 0.55748 0.40726 0.48646 -0.06017 -0.00122 0.04785  142 GLU A CG  
831  C CD  . GLU A 143 ? 0.64064 0.47454 0.57225 -0.07088 -0.00125 0.05620  142 GLU A CD  
832  O OE1 . GLU A 143 ? 0.55595 0.40101 0.49726 -0.07892 0.00449  0.06478  142 GLU A OE1 
833  O OE2 . GLU A 143 ? 0.60814 0.41823 0.53240 -0.07113 -0.00680 0.05448  142 GLU A OE2 
834  N N   . LEU A 144 ? 0.47161 0.37642 0.40815 -0.04793 0.01205  0.04711  143 LEU A N   
835  C CA  . LEU A 144 ? 0.42510 0.34923 0.37354 -0.05169 0.01469  0.04609  143 LEU A CA  
836  C C   . LEU A 144 ? 0.43132 0.36580 0.37997 -0.04425 0.01386  0.03820  143 LEU A C   
837  O O   . LEU A 144 ? 0.42052 0.36380 0.37706 -0.04610 0.01252  0.03389  143 LEU A O   
838  C CB  . LEU A 144 ? 0.42800 0.36367 0.37918 -0.05374 0.02209  0.05477  143 LEU A CB  
839  C CG  . LEU A 144 ? 0.43396 0.39039 0.39699 -0.05625 0.02531  0.05428  143 LEU A CG  
840  C CD1 . LEU A 144 ? 0.45085 0.40966 0.42604 -0.06543 0.02163  0.05291  143 LEU A CD1 
841  C CD2 . LEU A 144 ? 0.48052 0.44932 0.44504 -0.05640 0.03329  0.06300  143 LEU A CD2 
842  N N   . ALA A 145 ? 0.42459 0.35826 0.36496 -0.03584 0.01447  0.03651  144 ALA A N   
843  C CA  . ALA A 145 ? 0.41169 0.35385 0.35378 -0.02980 0.01331  0.02930  144 ALA A CA  
844  C C   . ALA A 145 ? 0.38853 0.32604 0.33242 -0.02923 0.00865  0.02327  144 ALA A C   
845  O O   . ALA A 145 ? 0.40465 0.35164 0.35458 -0.02809 0.00872  0.01901  144 ALA A O   
846  C CB  . ALA A 145 ? 0.35820 0.29910 0.29193 -0.02155 0.01303  0.02787  144 ALA A CB  
847  N N   . ARG A 146 ? 0.41302 0.33520 0.35057 -0.02904 0.00477  0.02304  145 ARG A N   
848  C CA  . ARG A 146 ? 0.43581 0.35297 0.37287 -0.02682 0.00031  0.01691  145 ARG A CA  
849  C C   . ARG A 146 ? 0.41492 0.33815 0.35999 -0.03280 -0.00056 0.01526  145 ARG A C   
850  O O   . ARG A 146 ? 0.38190 0.31215 0.32966 -0.02966 -0.00140 0.01042  145 ARG A O   
851  C CB  . ARG A 146 ? 0.44351 0.34073 0.37091 -0.02520 -0.00398 0.01697  145 ARG A CB  
852  C CG  . ARG A 146 ? 0.42311 0.31287 0.34811 -0.02269 -0.00910 0.01037  145 ARG A CG  
853  C CD  . ARG A 146 ? 0.46000 0.32709 0.37389 -0.02019 -0.01375 0.01006  145 ARG A CD  
854  N NE  . ARG A 146 ? 0.49448 0.35757 0.40056 -0.01231 -0.01275 0.01204  145 ARG A NE  
855  C CZ  . ARG A 146 ? 0.52274 0.37474 0.42264 -0.01336 -0.01176 0.01844  145 ARG A CZ  
856  N NH1 . ARG A 146 ? 0.49537 0.33716 0.39638 -0.02268 -0.01131 0.02419  145 ARG A NH1 
857  N NH2 . ARG A 146 ? 0.49828 0.35005 0.39107 -0.00475 -0.01121 0.01950  145 ARG A NH2 
858  N N   . SER A 147 ? 0.42827 0.34980 0.37759 -0.04127 -0.00034 0.01969  146 SER A N   
859  C CA  . SER A 147 ? 0.39759 0.32636 0.35539 -0.04711 -0.00216 0.01797  146 SER A CA  
860  C C   . SER A 147 ? 0.39276 0.34061 0.35766 -0.04504 0.00186  0.01730  146 SER A C   
861  O O   . SER A 147 ? 0.42685 0.38093 0.39461 -0.04353 0.00004  0.01305  146 SER A O   
862  C CB  . SER A 147 ? 0.43740 0.36347 0.40119 -0.05744 -0.00222 0.02389  146 SER A CB  
863  O OG  . SER A 147 ? 0.47772 0.41586 0.45200 -0.06293 -0.00369 0.02258  146 SER A OG  
864  N N   . PHE A 148 ? 0.36308 0.31942 0.32963 -0.04403 0.00730  0.02146  147 PHE A N   
865  C CA  . PHE A 148 ? 0.38812 0.35996 0.36042 -0.04145 0.01101  0.02071  147 PHE A CA  
866  C C   . PHE A 148 ? 0.38147 0.35431 0.35162 -0.03447 0.01033  0.01530  147 PHE A C   
867  O O   . PHE A 148 ? 0.37047 0.35148 0.34501 -0.03311 0.01080  0.01320  147 PHE A O   
868  C CB  . PHE A 148 ? 0.39053 0.36851 0.36240 -0.04022 0.01632  0.02521  147 PHE A CB  
869  C CG  . PHE A 148 ? 0.40990 0.39485 0.38746 -0.04641 0.01945  0.03170  147 PHE A CG  
870  C CD1 . PHE A 148 ? 0.36878 0.35318 0.35288 -0.05424 0.01675  0.03344  147 PHE A CD1 
871  C CD2 . PHE A 148 ? 0.41644 0.40970 0.39332 -0.04403 0.02503  0.03587  147 PHE A CD2 
872  C CE1 . PHE A 148 ? 0.46395 0.45771 0.45612 -0.06058 0.02010  0.04016  147 PHE A CE1 
873  C CE2 . PHE A 148 ? 0.42092 0.42340 0.40387 -0.04890 0.02907  0.04273  147 PHE A CE2 
874  C CZ  . PHE A 148 ? 0.41408 0.41765 0.40576 -0.05763 0.02690  0.04537  147 PHE A CZ  
875  N N   . PHE A 149 ? 0.35721 0.32267 0.32109 -0.02975 0.00947  0.01364  148 PHE A N   
876  C CA  . PHE A 149 ? 0.37158 0.34029 0.33586 -0.02372 0.00952  0.00948  148 PHE A CA  
877  C C   . PHE A 149 ? 0.38800 0.35533 0.35194 -0.02224 0.00690  0.00614  148 PHE A C   
878  O O   . PHE A 149 ? 0.37879 0.35402 0.34645 -0.01930 0.00870  0.00460  148 PHE A O   
879  C CB  . PHE A 149 ? 0.36488 0.32743 0.32351 -0.01899 0.00826  0.00836  148 PHE A CB  
880  C CG  . PHE A 149 ? 0.35674 0.32601 0.31905 -0.01378 0.00893  0.00496  148 PHE A CG  
881  C CD1 . PHE A 149 ? 0.34735 0.32592 0.31614 -0.01388 0.01188  0.00476  148 PHE A CD1 
882  C CD2 . PHE A 149 ? 0.36788 0.33400 0.32767 -0.00876 0.00661  0.00219  148 PHE A CD2 
883  C CE1 . PHE A 149 ? 0.34977 0.33410 0.32409 -0.01065 0.01234  0.00214  148 PHE A CE1 
884  C CE2 . PHE A 149 ? 0.36385 0.33845 0.32963 -0.00483 0.00768  -0.00004 148 PHE A CE2 
885  C CZ  . PHE A 149 ? 0.35364 0.33715 0.32745 -0.00655 0.01045  0.00009  148 PHE A CZ  
886  N N   . TRP A 150 ? 0.37481 0.33128 0.33352 -0.02389 0.00264  0.00512  149 TRP A N   
887  C CA  . TRP A 150 ? 0.36277 0.31688 0.31899 -0.02171 -0.00076 0.00107  149 TRP A CA  
888  C C   . TRP A 150 ? 0.37851 0.34394 0.34082 -0.02384 0.00028  0.00119  149 TRP A C   
889  O O   . TRP A 150 ? 0.38612 0.35707 0.34791 -0.01883 0.00091  -0.00106 149 TRP A O   
890  C CB  . TRP A 150 ? 0.34741 0.28604 0.29734 -0.02466 -0.00643 -0.00033 149 TRP A CB  
891  C CG  . TRP A 150 ? 0.40045 0.33396 0.34500 -0.02105 -0.01117 -0.00587 149 TRP A CG  
892  C CD1 . TRP A 150 ? 0.40313 0.33832 0.34938 -0.02455 -0.01503 -0.00831 149 TRP A CD1 
893  C CD2 . TRP A 150 ? 0.41212 0.33882 0.34787 -0.01206 -0.01299 -0.01019 149 TRP A CD2 
894  N NE1 . TRP A 150 ? 0.43529 0.36370 0.37269 -0.01789 -0.01944 -0.01437 149 TRP A NE1 
895  C CE2 . TRP A 150 ? 0.41616 0.33929 0.34687 -0.00994 -0.01783 -0.01536 149 TRP A CE2 
896  C CE3 . TRP A 150 ? 0.43507 0.35910 0.36659 -0.00497 -0.01135 -0.01040 149 TRP A CE3 
897  C CZ2 . TRP A 150 ? 0.47643 0.39307 0.39680 -0.00014 -0.02029 -0.02055 149 TRP A CZ2 
898  C CZ3 . TRP A 150 ? 0.43567 0.35480 0.35878 0.00437  -0.01354 -0.01508 149 TRP A CZ3 
899  C CH2 . TRP A 150 ? 0.46229 0.37721 0.37921 0.00695  -0.01770 -0.02002 149 TRP A CH2 
900  N N   . GLN A 151 ? 0.38715 0.35706 0.35519 -0.03062 0.00076  0.00438  150 GLN A N   
901  C CA  . GLN A 151 ? 0.37540 0.35720 0.34932 -0.03177 0.00125  0.00452  150 GLN A CA  
902  C C   . GLN A 151 ? 0.35745 0.34954 0.33439 -0.02676 0.00671  0.00569  150 GLN A C   
903  O O   . GLN A 151 ? 0.37016 0.36940 0.34824 -0.02369 0.00715  0.00488  150 GLN A O   
904  C CB  . GLN A 151 ? 0.38510 0.37246 0.36639 -0.03962 0.00130  0.00833  150 GLN A CB  
905  C CG  . GLN A 151 ? 0.39003 0.36789 0.37102 -0.04625 -0.00496 0.00714  150 GLN A CG  
906  C CD  . GLN A 151 ? 0.50302 0.49042 0.49462 -0.05466 -0.00479 0.01134  150 GLN A CD  
907  O OE1 . GLN A 151 ? 0.45977 0.46270 0.45823 -0.05403 -0.00236 0.01276  150 GLN A OE1 
908  N NE2 . GLN A 151 ? 0.46830 0.44683 0.46177 -0.06234 -0.00695 0.01402  150 GLN A NE2 
909  N N   . VAL A 152 ? 0.36787 0.36006 0.34573 -0.02567 0.01056  0.00757  151 VAL A N   
910  C CA  . VAL A 152 ? 0.36020 0.35958 0.34152 -0.02165 0.01503  0.00818  151 VAL A CA  
911  C C   . VAL A 152 ? 0.33568 0.33415 0.31482 -0.01620 0.01520  0.00594  151 VAL A C   
912  O O   . VAL A 152 ? 0.39469 0.39944 0.37640 -0.01312 0.01811  0.00689  151 VAL A O   
913  C CB  . VAL A 152 ? 0.35554 0.35440 0.33803 -0.02177 0.01772  0.00943  151 VAL A CB  
914  C CG1 . VAL A 152 ? 0.34755 0.35104 0.33423 -0.01827 0.02126  0.00913  151 VAL A CG1 
915  C CG2 . VAL A 152 ? 0.34408 0.34673 0.32842 -0.02557 0.01914  0.01260  151 VAL A CG2 
916  N N   . LEU A 153 ? 0.34171 0.33266 0.31583 -0.01422 0.01260  0.00360  152 LEU A N   
917  C CA  . LEU A 153 ? 0.33008 0.32211 0.30210 -0.00805 0.01331  0.00189  152 LEU A CA  
918  C C   . LEU A 153 ? 0.40823 0.40311 0.37691 -0.00538 0.01229  0.00100  152 LEU A C   
919  O O   . LEU A 153 ? 0.36775 0.36921 0.33752 -0.00064 0.01593  0.00233  152 LEU A O   
920  C CB  . LEU A 153 ? 0.38510 0.36839 0.35097 -0.00526 0.01006  -0.00080 152 LEU A CB  
921  C CG  . LEU A 153 ? 0.43013 0.41193 0.39832 -0.00590 0.01067  -0.00016 152 LEU A CG  
922  C CD1 . LEU A 153 ? 0.43920 0.41062 0.39956 -0.00286 0.00666  -0.00239 152 LEU A CD1 
923  C CD2 . LEU A 153 ? 0.51220 0.50333 0.48823 -0.00329 0.01465  0.00057  152 LEU A CD2 
924  N N   . GLU A 154 ? 0.35060 0.34061 0.31520 -0.00832 0.00713  -0.00112 153 GLU A N   
925  C CA  . GLU A 154 ? 0.39289 0.38576 0.35335 -0.00527 0.00457  -0.00317 153 GLU A CA  
926  C C   . GLU A 154 ? 0.36991 0.37442 0.33582 -0.00469 0.00857  0.00034  153 GLU A C   
927  O O   . GLU A 154 ? 0.40104 0.41050 0.36336 0.00144  0.00981  0.00047  153 GLU A O   
928  C CB  . GLU A 154 ? 0.40335 0.38872 0.36068 -0.01023 -0.00291 -0.00664 153 GLU A CB  
929  C CG  . GLU A 154 ? 0.44413 0.41486 0.39316 -0.00878 -0.00760 -0.01073 153 GLU A CG  
930  C CD  . GLU A 154 ? 0.46060 0.42858 0.39922 0.00072  -0.00980 -0.01542 153 GLU A CD  
931  O OE1 . GLU A 154 ? 0.47809 0.45130 0.41380 0.00350  -0.01203 -0.01749 153 GLU A OE1 
932  O OE2 . GLU A 154 ? 0.44495 0.40641 0.37771 0.00638  -0.00930 -0.01700 153 GLU A OE2 
933  N N   . ALA A 155 ? 0.34907 0.35776 0.32250 -0.00982 0.01097  0.00352  154 ALA A N   
934  C CA  . ALA A 155 ? 0.37692 0.39535 0.35485 -0.00836 0.01466  0.00685  154 ALA A CA  
935  C C   . ALA A 155 ? 0.41662 0.43722 0.39608 -0.00338 0.02098  0.00978  154 ALA A C   
936  O O   . ALA A 155 ? 0.38357 0.40972 0.36255 0.00112  0.02377  0.01231  154 ALA A O   
937  C CB  . ALA A 155 ? 0.34012 0.36220 0.32476 -0.01388 0.01579  0.00922  154 ALA A CB  
938  N N   . VAL A 156 ? 0.35921 0.37573 0.34113 -0.00424 0.02319  0.00986  155 VAL A N   
939  C CA  . VAL A 156 ? 0.39226 0.41108 0.37807 -0.00094 0.02872  0.01265  155 VAL A CA  
940  C C   . VAL A 156 ? 0.38296 0.40386 0.36375 0.00549  0.02995  0.01300  155 VAL A C   
941  O O   . VAL A 156 ? 0.41232 0.43772 0.39493 0.00935  0.03517  0.01717  155 VAL A O   
942  C CB  . VAL A 156 ? 0.41871 0.43422 0.40953 -0.00376 0.02937  0.01173  155 VAL A CB  
943  C CG1 . VAL A 156 ? 0.36589 0.38454 0.36324 -0.00162 0.03432  0.01433  155 VAL A CG1 
944  C CG2 . VAL A 156 ? 0.34713 0.36131 0.34108 -0.00819 0.02901  0.01175  155 VAL A CG2 
945  N N   . ARG A 157 ? 0.36916 0.38615 0.34279 0.00743  0.02552  0.00899  156 ARG A N   
946  C CA  . ARG A 157 ? 0.38406 0.40327 0.35045 0.01532  0.02647  0.00872  156 ARG A CA  
947  C C   . ARG A 157 ? 0.40493 0.42894 0.36630 0.01935  0.02664  0.01024  156 ARG A C   
948  O O   . ARG A 157 ? 0.36566 0.39480 0.32385 0.02638  0.03132  0.01368  156 ARG A O   
949  C CB  . ARG A 157 ? 0.36078 0.37255 0.31827 0.01747  0.02042  0.00293  156 ARG A CB  
950  C CG  . ARG A 157 ? 0.39072 0.39894 0.35073 0.01727  0.02076  0.00182  156 ARG A CG  
951  C CD  . ARG A 157 ? 0.42934 0.42805 0.37856 0.02096  0.01467  -0.00384 156 ARG A CD  
952  N NE  . ARG A 157 ? 0.39399 0.39449 0.33312 0.03032  0.01457  -0.00567 156 ARG A NE  
953  C CZ  . ARG A 157 ? 0.48251 0.47358 0.40941 0.03452  0.00800  -0.01176 156 ARG A CZ  
954  N NH1 . ARG A 157 ? 0.39459 0.37279 0.31877 0.02932  0.00118  -0.01595 156 ARG A NH1 
955  N NH2 . ARG A 157 ? 0.46536 0.45905 0.38183 0.04445  0.00822  -0.01358 156 ARG A NH2 
956  N N   . HIS A 158 ? 0.37100 0.39450 0.33179 0.01538  0.02166  0.00814  157 HIS A N   
957  C CA  . HIS A 158 ? 0.41537 0.44506 0.37229 0.01933  0.02086  0.00929  157 HIS A CA  
958  C C   . HIS A 158 ? 0.39747 0.43272 0.35910 0.02213  0.02878  0.01638  157 HIS A C   
959  O O   . HIS A 158 ? 0.45652 0.49619 0.41230 0.02980  0.03176  0.01954  157 HIS A O   
960  C CB  . HIS A 158 ? 0.40926 0.44000 0.36903 0.01306  0.01455  0.00649  157 HIS A CB  
961  C CG  . HIS A 158 ? 0.46248 0.50211 0.42118 0.01668  0.01385  0.00823  157 HIS A CG  
962  N ND1 . HIS A 158 ? 0.44509 0.48772 0.39445 0.02291  0.00882  0.00496  157 HIS A ND1 
963  C CD2 . HIS A 158 ? 0.48440 0.53061 0.44922 0.01618  0.01723  0.01264  157 HIS A CD2 
964  C CE1 . HIS A 158 ? 0.48550 0.53723 0.43583 0.02594  0.00902  0.00759  157 HIS A CE1 
965  N NE2 . HIS A 158 ? 0.50314 0.55699 0.46288 0.02210  0.01436  0.01249  157 HIS A NE2 
966  N N   . CYS A 159 ? 0.39396 0.42794 0.36519 0.01652  0.03217  0.01901  158 CYS A N   
967  C CA  . CYS A 159 ? 0.42414 0.46017 0.40022 0.01849  0.03923  0.02539  158 CYS A CA  
968  C C   . CYS A 159 ? 0.41768 0.45460 0.39327 0.02346  0.04551  0.02978  158 CYS A C   
969  O O   . CYS A 159 ? 0.44525 0.48517 0.41823 0.02927  0.05046  0.03549  158 CYS A O   
970  C CB  . CYS A 159 ? 0.34718 0.37948 0.33261 0.01192  0.04081  0.02579  158 CYS A CB  
971  S SG  . CYS A 159 ? 0.41955 0.45370 0.40670 0.00744  0.03624  0.02325  158 CYS A SG  
972  N N   . HIS A 160 ? 0.37196 0.40710 0.35051 0.02161  0.04585  0.02794  159 HIS A N   
973  C CA  . HIS A 160 ? 0.38731 0.42602 0.36768 0.02600  0.05236  0.03263  159 HIS A CA  
974  C C   . HIS A 160 ? 0.45076 0.49401 0.41890 0.03583  0.05339  0.03403  159 HIS A C   
975  O O   . HIS A 160 ? 0.41977 0.46748 0.38777 0.04121  0.06084  0.04127  159 HIS A O   
976  C CB  . HIS A 160 ? 0.40545 0.44356 0.39096 0.02322  0.05131  0.02945  159 HIS A CB  
977  C CG  . HIS A 160 ? 0.46330 0.49800 0.46041 0.01496  0.05078  0.02850  159 HIS A CG  
978  N ND1 . HIS A 160 ? 0.48670 0.52133 0.48948 0.01215  0.04905  0.02550  159 HIS A ND1 
979  C CD2 . HIS A 160 ? 0.44081 0.47194 0.44357 0.01004  0.05116  0.02956  159 HIS A CD2 
980  C CE1 . HIS A 160 ? 0.46124 0.49257 0.47244 0.00567  0.04809  0.02455  159 HIS A CE1 
981  N NE2 . HIS A 160 ? 0.37891 0.40755 0.38993 0.00438  0.04945  0.02680  159 HIS A NE2 
982  N N   . ASN A 161 ? 0.42484 0.46648 0.38221 0.03850  0.04589  0.02727  160 ASN A N   
983  C CA  . ASN A 161 ? 0.42539 0.47059 0.36881 0.04888  0.04518  0.02686  160 ASN A CA  
984  C C   . ASN A 161 ? 0.48274 0.53215 0.42226 0.05354  0.04779  0.03209  160 ASN A C   
985  O O   . ASN A 161 ? 0.46633 0.52037 0.39552 0.06369  0.05104  0.03544  160 ASN A O   
986  C CB  . ASN A 161 ? 0.48051 0.52092 0.41397 0.04945  0.03479  0.01728  160 ASN A CB  
987  C CG  . ASN A 161 ? 0.59916 0.63424 0.53171 0.04880  0.03241  0.01242  160 ASN A CG  
988  O OD1 . ASN A 161 ? 0.63560 0.67413 0.57059 0.05252  0.03862  0.01583  160 ASN A OD1 
989  N ND2 . ASN A 161 ? 0.60183 0.62881 0.53120 0.04432  0.02341  0.00479  160 ASN A ND2 
990  N N   . CYS A 162 ? 0.44932 0.49752 0.39567 0.04757  0.04645  0.03292  161 CYS A N   
991  C CA  . CYS A 162 ? 0.47219 0.52393 0.41588 0.05219  0.04905  0.03830  161 CYS A CA  
992  C C   . CYS A 162 ? 0.49297 0.54360 0.44404 0.05251  0.05943  0.04822  161 CYS A C   
993  O O   . CYS A 162 ? 0.51637 0.56789 0.46522 0.05671  0.06240  0.05372  161 CYS A O   
994  C CB  . CYS A 162 ? 0.45304 0.50494 0.40102 0.04646  0.04281  0.03457  161 CYS A CB  
995  S SG  . CYS A 162 ? 0.51911 0.57336 0.46009 0.04540  0.03015  0.02418  161 CYS A SG  
996  N N   . GLY A 163 ? 0.45774 0.50615 0.41822 0.04796  0.06451  0.05059  162 GLY A N   
997  C CA  . GLY A 163 ? 0.46774 0.51426 0.43742 0.04665  0.07381  0.05982  162 GLY A CA  
998  C C   . GLY A 163 ? 0.47324 0.51264 0.45445 0.03806  0.07356  0.05968  162 GLY A C   
999  O O   . GLY A 163 ? 0.44244 0.47760 0.42931 0.03769  0.08002  0.06707  162 GLY A O   
1000 N N   . VAL A 164 ? 0.42354 0.46057 0.40780 0.03155  0.06647  0.05168  163 VAL A N   
1001 C CA  . VAL A 164 ? 0.39877 0.42963 0.39065 0.02534  0.06525  0.05033  163 VAL A CA  
1002 C C   . VAL A 164 ? 0.39914 0.42699 0.39997 0.01722  0.06265  0.04520  163 VAL A C   
1003 O O   . VAL A 164 ? 0.42246 0.45256 0.42059 0.01571  0.05764  0.03947  163 VAL A O   
1004 C CB  . VAL A 164 ? 0.43525 0.46815 0.42124 0.02657  0.05936  0.04630  163 VAL A CB  
1005 C CG1 . VAL A 164 ? 0.41406 0.44163 0.40691 0.02110  0.05818  0.04418  163 VAL A CG1 
1006 C CG2 . VAL A 164 ? 0.42997 0.46673 0.40738 0.03554  0.06142  0.05141  163 VAL A CG2 
1007 N N   . LEU A 165 ? 0.41796 0.43978 0.42872 0.01241  0.06544  0.04695  164 LEU A N   
1008 C CA  . LEU A 165 ? 0.40261 0.42132 0.42156 0.00528  0.06217  0.04163  164 LEU A CA  
1009 C C   . LEU A 165 ? 0.36456 0.37716 0.38339 0.00281  0.05895  0.03804  164 LEU A C   
1010 O O   . LEU A 165 ? 0.41901 0.42556 0.43975 0.00372  0.06192  0.04126  164 LEU A O   
1011 C CB  . LEU A 165 ? 0.42909 0.44629 0.46046 0.00154  0.06681  0.04538  164 LEU A CB  
1012 C CG  . LEU A 165 ? 0.42036 0.43669 0.46094 -0.00506 0.06278  0.03961  164 LEU A CG  
1013 C CD1 . LEU A 165 ? 0.37840 0.40247 0.41604 -0.00374 0.05980  0.03606  164 LEU A CD1 
1014 C CD2 . LEU A 165 ? 0.41797 0.43215 0.47355 -0.01002 0.06676  0.04339  164 LEU A CD2 
1015 N N   . HIS A 166 ? 0.35895 0.37248 0.37515 0.00025  0.05331  0.03178  165 HIS A N   
1016 C CA  . HIS A 166 ? 0.37166 0.38186 0.38602 -0.00050 0.05095  0.02897  165 HIS A CA  
1017 C C   . HIS A 166 ? 0.42996 0.43182 0.45091 -0.00375 0.05119  0.02705  165 HIS A C   
1018 O O   . HIS A 166 ? 0.44409 0.44037 0.46413 -0.00189 0.05225  0.02748  165 HIS A O   
1019 C CB  . HIS A 166 ? 0.34547 0.35955 0.35517 -0.00233 0.04575  0.02426  165 HIS A CB  
1020 C CG  . HIS A 166 ? 0.35758 0.37158 0.36502 -0.00227 0.04424  0.02249  165 HIS A CG  
1021 N ND1 . HIS A 166 ? 0.36991 0.37848 0.37904 -0.00393 0.04347  0.01947  165 HIS A ND1 
1022 C CD2 . HIS A 166 ? 0.36295 0.38313 0.36671 -0.00031 0.04324  0.02321  165 HIS A CD2 
1023 C CE1 . HIS A 166 ? 0.39225 0.40361 0.39789 -0.00222 0.04297  0.01895  165 HIS A CE1 
1024 N NE2 . HIS A 166 ? 0.41213 0.43135 0.41569 -0.00051 0.04295  0.02148  165 HIS A NE2 
1025 N N   . ARG A 167 ? 0.37946 0.38037 0.40676 -0.00802 0.04952  0.02427  166 ARG A N   
1026 C CA  . ARG A 167 ? 0.35980 0.35339 0.39458 -0.01181 0.04816  0.02113  166 ARG A CA  
1027 C C   . ARG A 167 ? 0.39616 0.38501 0.42587 -0.01150 0.04403  0.01530  166 ARG A C   
1028 O O   . ARG A 167 ? 0.48641 0.46757 0.52023 -0.01341 0.04212  0.01170  166 ARG A O   
1029 C CB  . ARG A 167 ? 0.36684 0.35312 0.40825 -0.01212 0.05279  0.02594  166 ARG A CB  
1030 C CG  . ARG A 167 ? 0.36669 0.35804 0.41384 -0.01221 0.05810  0.03291  166 ARG A CG  
1031 C CD  . ARG A 167 ? 0.45597 0.43961 0.51489 -0.01585 0.06224  0.03750  166 ARG A CD  
1032 N NE  . ARG A 167 ? 0.47276 0.44563 0.52733 -0.01249 0.06507  0.04094  166 ARG A NE  
1033 C CZ  . ARG A 167 ? 0.49739 0.46031 0.55969 -0.01460 0.06933  0.04631  166 ARG A CZ  
1034 N NH1 . ARG A 167 ? 0.46087 0.42431 0.53780 -0.02134 0.07126  0.04889  166 ARG A NH1 
1035 N NH2 . ARG A 167 ? 0.49233 0.44484 0.54822 -0.00980 0.07185  0.04967  166 ARG A NH2 
1036 N N   . ASP A 168 ? 0.40655 0.39995 0.42766 -0.00913 0.04246  0.01419  167 ASP A N   
1037 C CA  . ASP A 168 ? 0.42211 0.41283 0.43793 -0.00805 0.03957  0.00961  167 ASP A CA  
1038 C C   . ASP A 168 ? 0.40625 0.40404 0.41593 -0.00825 0.03742  0.00889  167 ASP A C   
1039 O O   . ASP A 168 ? 0.42503 0.42546 0.42917 -0.00600 0.03761  0.00896  167 ASP A O   
1040 C CB  . ASP A 168 ? 0.41948 0.40624 0.43162 -0.00345 0.04195  0.01077  167 ASP A CB  
1041 C CG  . ASP A 168 ? 0.47496 0.45669 0.48197 -0.00113 0.03943  0.00538  167 ASP A CG  
1042 O OD1 . ASP A 168 ? 0.45796 0.43706 0.46522 -0.00345 0.03548  0.00036  167 ASP A OD1 
1043 O OD2 . ASP A 168 ? 0.45838 0.43944 0.46033 0.00413  0.04134  0.00607  167 ASP A OD2 
1044 N N   . ILE A 169 ? 0.36513 0.36597 0.37611 -0.01076 0.03567  0.00866  168 ILE A N   
1045 C CA  . ILE A 169 ? 0.40091 0.40533 0.40620 -0.01157 0.03322  0.00805  168 ILE A CA  
1046 C C   . ILE A 169 ? 0.37175 0.37327 0.37290 -0.01129 0.03064  0.00441  168 ILE A C   
1047 O O   . ILE A 169 ? 0.36281 0.36068 0.36622 -0.01176 0.02812  0.00066  168 ILE A O   
1048 C CB  . ILE A 169 ? 0.39853 0.40451 0.40500 -0.01298 0.03165  0.00806  168 ILE A CB  
1049 C CG1 . ILE A 169 ? 0.40841 0.41767 0.41686 -0.01166 0.03442  0.01159  168 ILE A CG1 
1050 C CG2 . ILE A 169 ? 0.37964 0.38593 0.37948 -0.01399 0.02871  0.00747  168 ILE A CG2 
1051 C CD1 . ILE A 169 ? 0.39042 0.40140 0.40074 -0.01128 0.03395  0.01148  168 ILE A CD1 
1052 N N   . LYS A 170 ? 0.38562 0.38982 0.38094 -0.01014 0.03128  0.00566  169 LYS A N   
1053 C CA  . LYS A 170 ? 0.40535 0.40792 0.39434 -0.00861 0.02970  0.00340  169 LYS A CA  
1054 C C   . LYS A 170 ? 0.35675 0.36529 0.34157 -0.00880 0.03169  0.00750  169 LYS A C   
1055 O O   . LYS A 170 ? 0.38334 0.39743 0.37133 -0.00994 0.03362  0.01088  169 LYS A O   
1056 C CB  . LYS A 170 ? 0.42286 0.42086 0.41042 -0.00489 0.02964  -0.00039 169 LYS A CB  
1057 C CG  . LYS A 170 ? 0.42809 0.42718 0.41634 -0.00180 0.03335  0.00155  169 LYS A CG  
1058 C CD  . LYS A 170 ? 0.39703 0.38888 0.38118 0.00302  0.03244  -0.00340 169 LYS A CD  
1059 C CE  . LYS A 170 ? 0.43319 0.42387 0.41743 0.00743  0.03600  -0.00176 169 LYS A CE  
1060 N NZ  . LYS A 170 ? 0.46448 0.44610 0.44281 0.01296  0.03444  -0.00750 169 LYS A NZ  
1061 N N   . ASP A 171 ? 0.38650 0.39466 0.36457 -0.00761 0.03117  0.00752  170 ASP A N   
1062 C CA  . ASP A 171 ? 0.39905 0.41366 0.37493 -0.00891 0.03374  0.01273  170 ASP A CA  
1063 C C   . ASP A 171 ? 0.43301 0.45581 0.41099 -0.00617 0.03781  0.01512  170 ASP A C   
1064 O O   . ASP A 171 ? 0.36816 0.39948 0.34997 -0.00886 0.03974  0.01977  170 ASP A O   
1065 C CB  . ASP A 171 ? 0.38793 0.40045 0.35518 -0.00731 0.03351  0.01368  170 ASP A CB  
1066 C CG  . ASP A 171 ? 0.43016 0.44000 0.39006 -0.00055 0.03323  0.00939  170 ASP A CG  
1067 O OD1 . ASP A 171 ? 0.41171 0.41986 0.37348 0.00244  0.03300  0.00532  170 ASP A OD1 
1068 O OD2 . ASP A 171 ? 0.39915 0.40740 0.35027 0.00221  0.03287  0.00997  170 ASP A OD2 
1069 N N   . GLU A 172 ? 0.39644 0.41677 0.37256 -0.00074 0.03869  0.01179  171 GLU A N   
1070 C CA  . GLU A 172 ? 0.45009 0.47774 0.42741 0.00354  0.04255  0.01389  171 GLU A CA  
1071 C C   . GLU A 172 ? 0.44483 0.47771 0.43008 0.00127  0.04316  0.01653  171 GLU A C   
1072 O O   . GLU A 172 ? 0.42506 0.46812 0.41282 0.00374  0.04606  0.01983  171 GLU A O   
1073 C CB  . GLU A 172 ? 0.41527 0.43554 0.38804 0.01039  0.04259  0.00892  171 GLU A CB  
1074 C CG  . GLU A 172 ? 0.40133 0.41514 0.36471 0.01426  0.04057  0.00430  171 GLU A CG  
1075 C CD  . GLU A 172 ? 0.53252 0.53750 0.49179 0.02093  0.03960  -0.00165 171 GLU A CD  
1076 O OE1 . GLU A 172 ? 0.56300 0.57164 0.52082 0.02666  0.04322  -0.00020 171 GLU A OE1 
1077 O OE2 . GLU A 172 ? 0.53787 0.53213 0.49603 0.02046  0.03487  -0.00793 171 GLU A OE2 
1078 N N   . ASN A 173 ? 0.36340 0.39076 0.35229 -0.00238 0.04056  0.01523  172 ASN A N   
1079 C CA  . ASN A 173 ? 0.39719 0.42876 0.39141 -0.00311 0.04087  0.01743  172 ASN A CA  
1080 C C   . ASN A 173 ? 0.34137 0.37820 0.33838 -0.00865 0.03862  0.01955  172 ASN A C   
1081 O O   . ASN A 173 ? 0.37682 0.41423 0.37626 -0.00943 0.03731  0.01983  172 ASN A O   
1082 C CB  . ASN A 173 ? 0.35574 0.37833 0.35164 -0.00224 0.04038  0.01538  172 ASN A CB  
1083 C CG  . ASN A 173 ? 0.46016 0.47708 0.45478 0.00315  0.04246  0.01394  172 ASN A CG  
1084 O OD1 . ASN A 173 ? 0.41936 0.44099 0.41148 0.00774  0.04458  0.01488  172 ASN A OD1 
1085 N ND2 . ASN A 173 ? 0.42978 0.43659 0.42648 0.00271  0.04186  0.01172  172 ASN A ND2 
1086 N N   . ILE A 174 ? 0.39319 0.43317 0.38924 -0.01213 0.03814  0.02116  173 ILE A N   
1087 C CA  . ILE A 174 ? 0.40565 0.44825 0.40439 -0.01814 0.03536  0.02285  173 ILE A CA  
1088 C C   . ILE A 174 ? 0.39494 0.44903 0.39748 -0.02043 0.03736  0.02730  173 ILE A C   
1089 O O   . ILE A 174 ? 0.38889 0.44391 0.38829 -0.01925 0.04027  0.02921  173 ILE A O   
1090 C CB  . ILE A 174 ? 0.39096 0.42301 0.38533 -0.02133 0.03253  0.02111  173 ILE A CB  
1091 C CG1 . ILE A 174 ? 0.41084 0.43497 0.40395 -0.01934 0.03076  0.01730  173 ILE A CG1 
1092 C CG2 . ILE A 174 ? 0.39197 0.42445 0.38826 -0.02759 0.02957  0.02301  173 ILE A CG2 
1093 C CD1 . ILE A 174 ? 0.41567 0.43081 0.40438 -0.01993 0.02854  0.01505  173 ILE A CD1 
1094 N N   . LEU A 175 ? 0.37695 0.44072 0.38643 -0.02346 0.03573  0.02907  174 LEU A N   
1095 C CA  . LEU A 175 ? 0.39234 0.46957 0.40906 -0.02737 0.03713  0.03381  174 LEU A CA  
1096 C C   . LEU A 175 ? 0.39299 0.46607 0.41250 -0.03638 0.03303  0.03475  174 LEU A C   
1097 O O   . LEU A 175 ? 0.41862 0.48372 0.43669 -0.03855 0.02793  0.03107  174 LEU A O   
1098 C CB  . LEU A 175 ? 0.41157 0.50413 0.43608 -0.02512 0.03700  0.03488  174 LEU A CB  
1099 C CG  . LEU A 175 ? 0.44055 0.53752 0.46286 -0.01546 0.04081  0.03452  174 LEU A CG  
1100 C CD1 . LEU A 175 ? 0.38011 0.49376 0.41059 -0.01340 0.03976  0.03617  174 LEU A CD1 
1101 C CD2 . LEU A 175 ? 0.45234 0.55173 0.47115 -0.01075 0.04650  0.03663  174 LEU A CD2 
1102 N N   . ILE A 176 ? 0.42653 0.50428 0.44945 -0.04112 0.03552  0.03995  175 ILE A N   
1103 C CA  . ILE A 176 ? 0.44259 0.51602 0.46976 -0.05070 0.03192  0.04202  175 ILE A CA  
1104 C C   . ILE A 176 ? 0.43104 0.52223 0.47262 -0.05673 0.03126  0.04577  175 ILE A C   
1105 O O   . ILE A 176 ? 0.42022 0.52639 0.46793 -0.05608 0.03697  0.05154  175 ILE A O   
1106 C CB  . ILE A 176 ? 0.39630 0.46163 0.41793 -0.05276 0.03537  0.04664  175 ILE A CB  
1107 C CG1 . ILE A 176 ? 0.36011 0.41138 0.36834 -0.04560 0.03588  0.04268  175 ILE A CG1 
1108 C CG2 . ILE A 176 ? 0.41219 0.46946 0.43789 -0.06298 0.03128  0.04897  175 ILE A CG2 
1109 C CD1 . ILE A 176 ? 0.41027 0.45794 0.41123 -0.04390 0.04050  0.04748  175 ILE A CD1 
1110 N N   . ASP A 177 ? 0.38838 0.47882 0.43551 -0.06223 0.02410  0.04237  176 ASP A N   
1111 C CA  . ASP A 177 ? 0.45718 0.56268 0.51978 -0.07078 0.02150  0.04551  176 ASP A CA  
1112 C C   . ASP A 177 ? 0.51980 0.61826 0.58613 -0.08078 0.02236  0.05115  176 ASP A C   
1113 O O   . ASP A 177 ? 0.48984 0.57074 0.55221 -0.08624 0.01672  0.04833  176 ASP A O   
1114 C CB  . ASP A 177 ? 0.40095 0.50619 0.46663 -0.07289 0.01225  0.03884  176 ASP A CB  
1115 C CG  . ASP A 177 ? 0.44573 0.56801 0.52923 -0.08227 0.00785  0.04089  176 ASP A CG  
1116 O OD1 . ASP A 177 ? 0.55187 0.67898 0.64557 -0.09122 0.01044  0.04750  176 ASP A OD1 
1117 O OD2 . ASP A 177 ? 0.53251 0.66386 0.62018 -0.08070 0.00167  0.03612  176 ASP A OD2 
1118 N N   . LEU A 178 ? 0.46514 0.57703 0.53857 -0.08253 0.02984  0.05965  177 LEU A N   
1119 C CA  . LEU A 178 ? 0.47292 0.57725 0.54777 -0.09050 0.03287  0.06700  177 LEU A CA  
1120 C C   . LEU A 178 ? 0.56643 0.66877 0.65479 -0.10448 0.02610  0.06802  177 LEU A C   
1121 O O   . LEU A 178 ? 0.65015 0.73604 0.73605 -0.11150 0.02549  0.07148  177 LEU A O   
1122 C CB  . LEU A 178 ? 0.50004 0.62191 0.57938 -0.08806 0.04336  0.07668  177 LEU A CB  
1123 C CG  . LEU A 178 ? 0.47558 0.59556 0.53943 -0.07446 0.04985  0.07573  177 LEU A CG  
1124 C CD1 . LEU A 178 ? 0.50765 0.64853 0.57656 -0.07059 0.05968  0.08439  177 LEU A CD1 
1125 C CD2 . LEU A 178 ? 0.44997 0.54620 0.49727 -0.07230 0.04975  0.07472  177 LEU A CD2 
1126 N N   . ASN A 179 ? 0.53215 0.65027 0.63468 -0.10858 0.02053  0.06500  178 ASN A N   
1127 C CA  . ASN A 179 ? 0.51901 0.63593 0.63612 -0.12280 0.01295  0.06522  178 ASN A CA  
1128 C C   . ASN A 179 ? 0.56216 0.65569 0.66945 -0.12396 0.00196  0.05488  178 ASN A C   
1129 O O   . ASN A 179 ? 0.50471 0.58309 0.61541 -0.13446 -0.00371 0.05477  178 ASN A O   
1130 C CB  . ASN A 179 ? 0.56561 0.71144 0.70358 -0.12707 0.01054  0.06604  178 ASN A CB  
1131 C CG  . ASN A 179 ? 0.62110 0.78840 0.77681 -0.13412 0.01910  0.07843  178 ASN A CG  
1132 O OD1 . ASN A 179 ? 0.68555 0.84637 0.83567 -0.13408 0.02797  0.08681  178 ASN A OD1 
1133 N N   . ARG A 180 ? 0.46686 0.55650 0.56156 -0.11291 -0.00088 0.04644  179 ARG A N   
1134 C CA  . ARG A 180 ? 0.47952 0.54946 0.56373 -0.11178 -0.01054 0.03661  179 ARG A CA  
1135 C C   . ARG A 180 ? 0.50129 0.54726 0.56629 -0.10511 -0.00832 0.03475  179 ARG A C   
1136 O O   . ARG A 180 ? 0.43361 0.46108 0.48937 -0.10450 -0.01560 0.02768  179 ARG A O   
1137 C CB  . ARG A 180 ? 0.51679 0.59804 0.59929 -0.10363 -0.01532 0.02898  179 ARG A CB  
1138 C CG  . ARG A 180 ? 0.63317 0.73871 0.73490 -0.10978 -0.01982 0.02940  179 ARG A CG  
1139 C CD  . ARG A 180 ? 0.56960 0.68682 0.66807 -0.10012 -0.02419 0.02271  179 ARG A CD  
1140 N NE  . ARG A 180 ? 0.59656 0.69440 0.67897 -0.09464 -0.03124 0.01356  179 ARG A NE  
1141 C CZ  . ARG A 180 ? 0.73471 0.82581 0.81775 -0.09923 -0.04288 0.00585  179 ARG A CZ  
1142 N NH1 . ARG A 180 ? 0.69889 0.80079 0.79947 -0.11077 -0.04988 0.00565  179 ARG A NH1 
1143 N NH2 . ARG A 180 ? 0.74341 0.81691 0.80935 -0.09194 -0.04779 -0.00202 179 ARG A NH2 
1144 N N   . GLY A 181 ? 0.45422 0.50052 0.51298 -0.09970 0.00104  0.04058  180 GLY A N   
1145 C CA  . GLY A 181 ? 0.46981 0.49619 0.51167 -0.09289 0.00262  0.03855  180 GLY A CA  
1146 C C   . GLY A 181 ? 0.53882 0.56183 0.57008 -0.08246 0.00019  0.03038  180 GLY A C   
1147 O O   . GLY A 181 ? 0.50296 0.50851 0.52227 -0.07840 -0.00225 0.02619  180 GLY A O   
1148 N N   . GLU A 182 ? 0.43455 0.47434 0.47026 -0.07771 0.00108  0.02861  181 GLU A N   
1149 C CA  . GLU A 182 ? 0.44592 0.48430 0.47305 -0.06815 -0.00035 0.02237  181 GLU A CA  
1150 C C   . GLU A 182 ? 0.44186 0.48769 0.46598 -0.06005 0.00758  0.02495  181 GLU A C   
1151 O O   . GLU A 182 ? 0.45960 0.52018 0.49111 -0.06017 0.01240  0.02968  181 GLU A O   
1152 C CB  . GLU A 182 ? 0.43823 0.48814 0.47113 -0.06788 -0.00623 0.01815  181 GLU A CB  
1153 C CG  . GLU A 182 ? 0.51287 0.55434 0.54720 -0.07453 -0.01608 0.01303  181 GLU A CG  
1154 C CD  . GLU A 182 ? 0.61240 0.66929 0.65434 -0.07470 -0.02235 0.00929  181 GLU A CD  
1155 O OE1 . GLU A 182 ? 0.62404 0.69969 0.67225 -0.07081 -0.01822 0.01235  181 GLU A OE1 
1156 O OE2 . GLU A 182 ? 0.63721 0.68711 0.67815 -0.07801 -0.03187 0.00294  181 GLU A OE2 
1157 N N   . LEU A 183 ? 0.39994 0.43580 0.41370 -0.05289 0.00869  0.02165  182 LEU A N   
1158 C CA  . LEU A 183 ? 0.36913 0.40890 0.37982 -0.04555 0.01487  0.02276  182 LEU A CA  
1159 C C   . LEU A 183 ? 0.36489 0.41140 0.37544 -0.03925 0.01459  0.02009  182 LEU A C   
1160 O O   . LEU A 183 ? 0.38893 0.43164 0.39631 -0.03791 0.01001  0.01616  182 LEU A O   
1161 C CB  . LEU A 183 ? 0.39238 0.41831 0.39392 -0.04222 0.01623  0.02127  182 LEU A CB  
1162 C CG  . LEU A 183 ? 0.44294 0.46517 0.44246 -0.04427 0.01958  0.02539  182 LEU A CG  
1163 C CD1 . LEU A 183 ? 0.45073 0.47112 0.45438 -0.05275 0.01760  0.02915  182 LEU A CD1 
1164 C CD2 . LEU A 183 ? 0.42843 0.43779 0.41888 -0.04019 0.01926  0.02283  182 LEU A CD2 
1165 N N   . LYS A 184 ? 0.38050 0.43617 0.39324 -0.03450 0.01965  0.02240  183 LYS A N   
1166 C CA  . LYS A 184 ? 0.39431 0.45617 0.40687 -0.02801 0.02032  0.02140  183 LYS A CA  
1167 C C   . LYS A 184 ? 0.34894 0.40641 0.35755 -0.02179 0.02574  0.02191  183 LYS A C   
1168 O O   . LYS A 184 ? 0.38431 0.44415 0.39387 -0.02090 0.02962  0.02400  183 LYS A O   
1169 C CB  . LYS A 184 ? 0.39346 0.47245 0.41435 -0.02801 0.02016  0.02385  183 LYS A CB  
1170 C CG  . LYS A 184 ? 0.44013 0.52584 0.46816 -0.03551 0.01392  0.02317  183 LYS A CG  
1171 C CD  . LYS A 184 ? 0.46172 0.54404 0.48554 -0.03377 0.00736  0.01823  183 LYS A CD  
1172 C CE  . LYS A 184 ? 0.45152 0.54228 0.48378 -0.04095 -0.00032 0.01642  183 LYS A CE  
1173 N NZ  . LYS A 184 ? 0.54092 0.62457 0.56596 -0.03887 -0.00768 0.01024  183 LYS A NZ  
1174 N N   . LEU A 185 ? 0.39201 0.44347 0.39639 -0.01730 0.02598  0.02012  184 LEU A N   
1175 C CA  . LEU A 185 ? 0.34890 0.39545 0.35139 -0.01237 0.03049  0.02058  184 LEU A CA  
1176 C C   . LEU A 185 ? 0.41882 0.47297 0.42334 -0.00697 0.03359  0.02306  184 LEU A C   
1177 O O   . LEU A 185 ? 0.40936 0.47154 0.41502 -0.00461 0.03213  0.02409  184 LEU A O   
1178 C CB  . LEU A 185 ? 0.33714 0.37635 0.33633 -0.00998 0.03036  0.01919  184 LEU A CB  
1179 C CG  . LEU A 185 ? 0.54588 0.57557 0.54328 -0.01142 0.03035  0.01713  184 LEU A CG  
1180 C CD1 . LEU A 185 ? 0.48146 0.50882 0.47769 -0.00769 0.03180  0.01748  184 LEU A CD1 
1181 C CD2 . LEU A 185 ? 0.53048 0.55626 0.52916 -0.01154 0.03285  0.01680  184 LEU A CD2 
1182 N N   . ILE A 186 ? 0.40906 0.45989 0.41305 -0.00401 0.03739  0.02355  185 ILE A N   
1183 C CA  . ILE A 186 ? 0.42102 0.47625 0.42551 0.00245  0.04056  0.02568  185 ILE A CA  
1184 C C   . ILE A 186 ? 0.44397 0.48688 0.44593 0.00611  0.04355  0.02500  185 ILE A C   
1185 O O   . ILE A 186 ? 0.40954 0.44296 0.41077 0.00314  0.04309  0.02260  185 ILE A O   
1186 C CB  . ILE A 186 ? 0.40381 0.46889 0.41046 0.00364  0.04224  0.02705  185 ILE A CB  
1187 C CG1 . ILE A 186 ? 0.38744 0.44556 0.39102 0.00226  0.04365  0.02526  185 ILE A CG1 
1188 C CG2 . ILE A 186 ? 0.43002 0.50886 0.44227 -0.00103 0.03940  0.02859  185 ILE A CG2 
1189 C CD1 . ILE A 186 ? 0.42594 0.49332 0.42961 0.00608  0.04686  0.02705  185 ILE A CD1 
1190 N N   . ASP A 187 ? 0.37775 0.42106 0.37897 0.01268  0.04629  0.02721  186 ASP A N   
1191 C CA  . ASP A 187 ? 0.42507 0.45601 0.42444 0.01667  0.04921  0.02695  186 ASP A CA  
1192 C C   . ASP A 187 ? 0.42168 0.44215 0.42218 0.01446  0.04987  0.02750  186 ASP A C   
1193 O O   . ASP A 187 ? 0.39321 0.40569 0.39536 0.01013  0.04896  0.02458  186 ASP A O   
1194 C CB  . ASP A 187 ? 0.42413 0.44949 0.42165 0.01637  0.04924  0.02321  186 ASP A CB  
1195 C CG  . ASP A 187 ? 0.58085 0.59444 0.57565 0.02240  0.05153  0.02228  186 ASP A CG  
1196 O OD1 . ASP A 187 ? 0.54853 0.55588 0.54393 0.02519  0.05343  0.02520  186 ASP A OD1 
1197 O OD2 . ASP A 187 ? 0.60145 0.61121 0.59264 0.02489  0.05141  0.01877  186 ASP A OD2 
1198 N N   . PHE A 188 ? 0.38584 0.40741 0.38561 0.01817  0.05171  0.03171  187 PHE A N   
1199 C CA  . PHE A 188 ? 0.45013 0.46350 0.45125 0.01749  0.05411  0.03436  187 PHE A CA  
1200 C C   . PHE A 188 ? 0.49475 0.49510 0.49661 0.02068  0.05788  0.03667  187 PHE A C   
1201 O O   . PHE A 188 ? 0.50381 0.49793 0.50737 0.02108  0.06124  0.04112  187 PHE A O   
1202 C CB  . PHE A 188 ? 0.43213 0.45345 0.43026 0.02079  0.05441  0.03823  187 PHE A CB  
1203 C CG  . PHE A 188 ? 0.46577 0.49534 0.46328 0.01670  0.05010  0.03516  187 PHE A CG  
1204 C CD1 . PHE A 188 ? 0.47488 0.51435 0.47208 0.01541  0.04599  0.03257  187 PHE A CD1 
1205 C CD2 . PHE A 188 ? 0.40883 0.43596 0.40663 0.01411  0.05021  0.03497  187 PHE A CD2 
1206 C CE1 . PHE A 188 ? 0.44062 0.48467 0.43735 0.01095  0.04150  0.02954  187 PHE A CE1 
1207 C CE2 . PHE A 188 ? 0.39167 0.42383 0.38754 0.01120  0.04581  0.03153  187 PHE A CE2 
1208 C CZ  . PHE A 188 ? 0.44778 0.48701 0.44284 0.00932  0.04117  0.02866  187 PHE A CZ  
1209 N N   . GLY A 189 ? 0.49216 0.48763 0.49256 0.02311  0.05754  0.03390  188 GLY A N   
1210 C CA  . GLY A 189 ? 0.54979 0.53036 0.54969 0.02675  0.06015  0.03497  188 GLY A CA  
1211 C C   . GLY A 189 ? 0.62845 0.59526 0.63458 0.02049  0.06041  0.03375  188 GLY A C   
1212 O O   . GLY A 189 ? 0.55799 0.51058 0.56521 0.02227  0.06282  0.03595  188 GLY A O   
1213 N N   . SER A 190 ? 0.47209 0.44264 0.48296 0.01324  0.05777  0.03042  189 SER A N   
1214 C CA  . SER A 190 ? 0.50957 0.47109 0.52892 0.00672  0.05764  0.02952  189 SER A CA  
1215 C C   . SER A 190 ? 0.44918 0.41814 0.47358 0.00339  0.06001  0.03428  189 SER A C   
1216 O O   . SER A 190 ? 0.47206 0.43862 0.50528 -0.00259 0.05978  0.03365  189 SER A O   
1217 C CB  . SER A 190 ? 0.54120 0.50111 0.56219 0.00225  0.05226  0.02123  189 SER A CB  
1218 O OG  . SER A 190 ? 0.60884 0.56169 0.62365 0.00660  0.05030  0.01651  189 SER A OG  
1219 N N   . GLY A 191 ? 0.42907 0.40788 0.44805 0.00771  0.06197  0.03868  190 GLY A N   
1220 C CA  . GLY A 191 ? 0.42819 0.41486 0.44903 0.00646  0.06382  0.04225  190 GLY A CA  
1221 C C   . GLY A 191 ? 0.49986 0.48126 0.52529 0.00720  0.07017  0.05030  190 GLY A C   
1222 O O   . GLY A 191 ? 0.47562 0.44511 0.50416 0.00732  0.07291  0.05319  190 GLY A O   
1223 N N   . ALA A 192 ? 0.43474 0.42473 0.46005 0.00811  0.07277  0.05425  191 ALA A N   
1224 C CA  . ALA A 192 ? 0.47707 0.46519 0.50616 0.00953  0.08008  0.06350  191 ALA A CA  
1225 C C   . ALA A 192 ? 0.49886 0.49934 0.52100 0.01471  0.08182  0.06653  191 ALA A C   
1226 O O   . ALA A 192 ? 0.45211 0.46063 0.47019 0.01452  0.07679  0.06043  191 ALA A O   
1227 C CB  . ALA A 192 ? 0.42457 0.40807 0.46868 0.00119  0.08191  0.06424  191 ALA A CB  
1228 N N   . LEU A 193 ? 0.44109 0.44196 0.46077 0.02001  0.08899  0.07612  192 LEU A N   
1229 C CA  . LEU A 193 ? 0.41026 0.42250 0.42358 0.02546  0.09141  0.07917  192 LEU A CA  
1230 C C   . LEU A 193 ? 0.44162 0.45966 0.46475 0.01943  0.09110  0.07635  192 LEU A C   
1231 O O   . LEU A 193 ? 0.44784 0.46162 0.48510 0.01183  0.09296  0.07735  192 LEU A O   
1232 C CB  . LEU A 193 ? 0.47796 0.48943 0.48764 0.03233  0.10058  0.09136  192 LEU A CB  
1233 C CG  . LEU A 193 ? 0.55432 0.56062 0.55289 0.04052  0.10142  0.09549  192 LEU A CG  
1234 C CD1 . LEU A 193 ? 0.51773 0.52159 0.51322 0.04705  0.11155  0.10902  192 LEU A CD1 
1235 C CD2 . LEU A 193 ? 0.51608 0.53206 0.50074 0.04761  0.09453  0.08925  192 LEU A CD2 
1236 N N   . LEU A 194 ? 0.44308 0.47061 0.45890 0.02297  0.08793  0.07212  193 LEU A N   
1237 C CA  . LEU A 194 ? 0.42045 0.45436 0.44426 0.01922  0.08769  0.06960  193 LEU A CA  
1238 C C   . LEU A 194 ? 0.46672 0.50670 0.49722 0.02134  0.09738  0.07975  193 LEU A C   
1239 O O   . LEU A 194 ? 0.47480 0.51896 0.49535 0.03010  0.10272  0.08647  193 LEU A O   
1240 C CB  . LEU A 194 ? 0.45238 0.49249 0.46500 0.02351  0.08158  0.06230  193 LEU A CB  
1241 C CG  . LEU A 194 ? 0.48066 0.52762 0.49898 0.02210  0.08112  0.05952  193 LEU A CG  
1242 C CD1 . LEU A 194 ? 0.45426 0.49767 0.48609 0.01250  0.07746  0.05482  193 LEU A CD1 
1243 C CD2 . LEU A 194 ? 0.51556 0.56525 0.52026 0.02762  0.07493  0.05248  193 LEU A CD2 
1244 N N   . LYS A 195 ? 0.44559 0.48725 0.49318 0.01363  0.09967  0.08109  194 LYS A N   
1245 C CA  . LYS A 195 ? 0.48296 0.53345 0.54028 0.01445  0.10924  0.09112  194 LYS A CA  
1246 C C   . LYS A 195 ? 0.47211 0.53273 0.54198 0.00983  0.10715  0.08674  194 LYS A C   
1247 O O   . LYS A 195 ? 0.44202 0.49959 0.51535 0.00431  0.09874  0.07703  194 LYS A O   
1248 C CB  . LYS A 195 ? 0.47592 0.51821 0.54636 0.00849  0.11607  0.10052  194 LYS A CB  
1249 C CG  . LYS A 195 ? 0.48591 0.52055 0.57364 -0.00384 0.11081  0.09469  194 LYS A CG  
1250 C CD  . LYS A 195 ? 0.55444 0.57624 0.65292 -0.00969 0.11589  0.10249  194 LYS A CD  
1251 C CE  . LYS A 195 ? 0.45456 0.46935 0.57096 -0.02185 0.10994  0.09585  194 LYS A CE  
1252 N NZ  . LYS A 195 ? 0.47473 0.47309 0.59991 -0.02740 0.11361  0.10217  194 LYS A NZ  
1253 N N   . ASP A 196 ? 0.47098 0.54474 0.54736 0.01304  0.11523  0.09450  195 ASP A N   
1254 C CA  . ASP A 196 ? 0.41047 0.49688 0.50011 0.01004  0.11430  0.09167  195 ASP A CA  
1255 C C   . ASP A 196 ? 0.50453 0.59363 0.62029 -0.00153 0.11763  0.09643  195 ASP A C   
1256 O O   . ASP A 196 ? 0.45067 0.55126 0.58062 -0.00533 0.11569  0.09342  195 ASP A O   
1257 C CB  . ASP A 196 ? 0.50032 0.60210 0.58284 0.02112  0.12104  0.09681  195 ASP A CB  
1258 C CG  . ASP A 196 ? 0.52400 0.62298 0.58131 0.03224  0.11561  0.08972  195 ASP A CG  
1259 O OD1 . ASP A 196 ? 0.55265 0.64487 0.60391 0.03022  0.10541  0.07857  195 ASP A OD1 
1260 O OD2 . ASP A 196 ? 0.64721 0.75070 0.69070 0.04312  0.12145  0.09542  195 ASP A OD2 
1261 N N   . THR A 197 ? 0.49220 0.57073 0.61487 -0.00704 0.12206  0.10354  196 THR A N   
1262 C CA  . THR A 197 ? 0.47425 0.55187 0.62225 -0.01936 0.12426  0.10766  196 THR A CA  
1263 C C   . THR A 197 ? 0.47009 0.53410 0.62263 -0.02823 0.11288  0.09590  196 THR A C   
1264 O O   . THR A 197 ? 0.40857 0.46459 0.54481 -0.02461 0.10485  0.08628  196 THR A O   
1265 C CB  . THR A 197 ? 0.45267 0.52312 0.60491 -0.02045 0.13493  0.12176  196 THR A CB  
1266 O OG1 . THR A 197 ? 0.46295 0.51778 0.59422 -0.01398 0.13352  0.12110  196 THR A OG1 
1267 C CG2 . THR A 197 ? 0.47091 0.55844 0.62397 -0.01306 0.14731  0.13464  196 THR A CG2 
1268 N N   . VAL A 198 ? 0.42771 0.48928 0.60272 -0.03989 0.11202  0.09661  197 VAL A N   
1269 C CA  . VAL A 198 ? 0.42467 0.47593 0.60457 -0.04750 0.10047  0.08430  197 VAL A CA  
1270 C C   . VAL A 198 ? 0.47631 0.50489 0.64437 -0.04753 0.09789  0.08219  197 VAL A C   
1271 O O   . VAL A 198 ? 0.46058 0.47967 0.62786 -0.04701 0.10537  0.09192  197 VAL A O   
1272 C CB  . VAL A 198 ? 0.45325 0.51057 0.66202 -0.05993 0.09890  0.08437  197 VAL A CB  
1273 C CG1 . VAL A 198 ? 0.50734 0.55269 0.73031 -0.06799 0.10559  0.09440  197 VAL A CG1 
1274 C CG2 . VAL A 198 ? 0.48406 0.53563 0.69538 -0.06519 0.08545  0.06962  197 VAL A CG2 
1275 N N   . TYR A 199 ? 0.46048 0.48060 0.61875 -0.04728 0.08764  0.06993  198 TYR A N   
1276 C CA  . TYR A 199 ? 0.44870 0.44851 0.59760 -0.04742 0.08390  0.06603  198 TYR A CA  
1277 C C   . TYR A 199 ? 0.45725 0.44659 0.62208 -0.05781 0.07736  0.05972  198 TYR A C   
1278 O O   . TYR A 199 ? 0.44391 0.44086 0.61763 -0.06229 0.06996  0.05133  198 TYR A O   
1279 C CB  . TYR A 199 ? 0.41689 0.41437 0.54500 -0.04025 0.07715  0.05687  198 TYR A CB  
1280 C CG  . TYR A 199 ? 0.38935 0.39297 0.49984 -0.03020 0.08147  0.06122  198 TYR A CG  
1281 C CD1 . TYR A 199 ? 0.42791 0.44681 0.53482 -0.02604 0.08192  0.06088  198 TYR A CD1 
1282 C CD2 . TYR A 199 ? 0.43149 0.42535 0.52838 -0.02425 0.08411  0.06472  198 TYR A CD2 
1283 C CE1 . TYR A 199 ? 0.42523 0.44854 0.51552 -0.01691 0.08438  0.06335  198 TYR A CE1 
1284 C CE2 . TYR A 199 ? 0.41411 0.41452 0.49529 -0.01514 0.08655  0.06754  198 TYR A CE2 
1285 C CZ  . TYR A 199 ? 0.42002 0.43466 0.49804 -0.01188 0.08641  0.06652  198 TYR A CZ  
1286 O OH  . TYR A 199 ? 0.42435 0.44439 0.48659 -0.00302 0.08748  0.06795  198 TYR A OH  
1287 N N   . THR A 200 ? 0.50157 0.47248 0.66879 -0.06088 0.07932  0.06312  199 THR A N   
1288 C CA  . THR A 200 ? 0.50787 0.46474 0.68792 -0.07013 0.07203  0.05591  199 THR A CA  
1289 C C   . THR A 200 ? 0.58772 0.52376 0.75136 -0.06574 0.06640  0.04829  199 THR A C   
1290 O O   . THR A 200 ? 0.56210 0.48277 0.73302 -0.07182 0.06001  0.04161  199 THR A O   
1291 C CB  . THR A 200 ? 0.56835 0.51925 0.77003 -0.07969 0.07848  0.06611  199 THR A CB  
1292 O OG1 . THR A 200 ? 0.52554 0.46731 0.71770 -0.07396 0.08872  0.07844  199 THR A OG1 
1293 C CG2 . THR A 200 ? 0.52617 0.50022 0.74855 -0.08549 0.08271  0.07202  199 THR A CG2 
1294 N N   . ASP A 201 ? 0.53773 0.47344 0.67989 -0.05511 0.06829  0.04880  200 ASP A N   
1295 C CA  . ASP A 201 ? 0.60329 0.52350 0.72905 -0.04910 0.06377  0.04211  200 ASP A CA  
1296 C C   . ASP A 201 ? 0.45775 0.38888 0.56871 -0.04279 0.05841  0.03390  200 ASP A C   
1297 O O   . ASP A 201 ? 0.51080 0.45856 0.61895 -0.04024 0.06063  0.03645  200 ASP A O   
1298 C CB  . ASP A 201 ? 0.59477 0.50500 0.70913 -0.04163 0.07151  0.05157  200 ASP A CB  
1299 C CG  . ASP A 201 ? 0.69786 0.62419 0.80003 -0.03317 0.07711  0.05793  200 ASP A CG  
1300 O OD1 . ASP A 201 ? 0.69949 0.63979 0.80883 -0.03474 0.08244  0.06491  200 ASP A OD1 
1301 O OD2 . ASP A 201 ? 0.67302 0.59871 0.75855 -0.02464 0.07584  0.05555  200 ASP A OD2 
1302 N N   . PHE A 202 ? 0.48435 0.40547 0.58540 -0.03991 0.05155  0.02430  201 PHE A N   
1303 C CA  . PHE A 202 ? 0.50548 0.43587 0.59243 -0.03405 0.04725  0.01770  201 PHE A CA  
1304 C C   . PHE A 202 ? 0.53354 0.45093 0.60739 -0.02834 0.04319  0.01085  201 PHE A C   
1305 O O   . PHE A 202 ? 0.55567 0.45887 0.63309 -0.03105 0.03821  0.00443  201 PHE A O   
1306 C CB  . PHE A 202 ? 0.42308 0.36458 0.51692 -0.03870 0.04087  0.01069  201 PHE A CB  
1307 C CG  . PHE A 202 ? 0.47992 0.42872 0.55934 -0.03314 0.03658  0.00457  201 PHE A CG  
1308 C CD1 . PHE A 202 ? 0.46040 0.42147 0.53197 -0.02899 0.04004  0.00892  201 PHE A CD1 
1309 C CD2 . PHE A 202 ? 0.47908 0.42178 0.55245 -0.03190 0.02905  -0.00534 201 PHE A CD2 
1310 C CE1 . PHE A 202 ? 0.46644 0.43309 0.52610 -0.02501 0.03639  0.00424  201 PHE A CE1 
1311 C CE2 . PHE A 202 ? 0.47913 0.42860 0.53932 -0.02678 0.02620  -0.00938 201 PHE A CE2 
1312 C CZ  . PHE A 202 ? 0.40999 0.37120 0.46430 -0.02403 0.03003  -0.00420 201 PHE A CZ  
1313 N N   . ASP A 203 ? 0.48655 0.40951 0.54561 -0.02026 0.04503  0.01191  202 ASP A N   
1314 C CA  . ASP A 203 ? 0.49837 0.41312 0.54423 -0.01311 0.04253  0.00662  202 ASP A CA  
1315 C C   . ASP A 203 ? 0.56248 0.49065 0.59744 -0.00868 0.04048  0.00330  202 ASP A C   
1316 O O   . ASP A 203 ? 0.51748 0.44452 0.54114 -0.00148 0.04073  0.00179  202 ASP A O   
1317 C CB  . ASP A 203 ? 0.56067 0.46725 0.60036 -0.00654 0.04831  0.01336  202 ASP A CB  
1318 C CG  . ASP A 203 ? 0.66750 0.55460 0.71493 -0.00963 0.04955  0.01545  202 ASP A CG  
1319 N N   . GLY A 204 ? 0.52054 0.46152 0.55898 -0.01257 0.03889  0.00282  203 GLY A N   
1320 C CA  . GLY A 204 ? 0.44479 0.39651 0.47391 -0.00959 0.03681  0.00018  203 GLY A CA  
1321 C C   . GLY A 204 ? 0.53048 0.47823 0.55513 -0.00897 0.03038  -0.00885 203 GLY A C   
1322 O O   . GLY A 204 ? 0.49904 0.43437 0.52417 -0.00856 0.02721  -0.01418 203 GLY A O   
1323 N N   . THR A 205 ? 0.46181 0.41927 0.48116 -0.00846 0.02811  -0.01069 204 THR A N   
1324 C CA  . THR A 205 ? 0.43751 0.39296 0.44907 -0.00581 0.02266  -0.01824 204 THR A CA  
1325 C C   . THR A 205 ? 0.44195 0.39708 0.46168 -0.01090 0.01661  -0.02362 204 THR A C   
1326 O O   . THR A 205 ? 0.43815 0.40226 0.46355 -0.01446 0.01654  -0.02118 204 THR A O   
1327 C CB  . THR A 205 ? 0.47079 0.43630 0.47196 -0.00225 0.02391  -0.01625 204 THR A CB  
1328 O OG1 . THR A 205 ? 0.49016 0.45785 0.48567 0.00242  0.02889  -0.01184 204 THR A OG1 
1329 C CG2 . THR A 205 ? 0.45508 0.41900 0.44693 0.00142  0.01912  -0.02281 204 THR A CG2 
1330 N N   . ARG A 206 ? 0.44508 0.39018 0.46500 -0.01055 0.01092  -0.03152 205 ARG A N   
1331 C CA  . ARG A 206 ? 0.45810 0.40309 0.48944 -0.01634 0.00440  -0.03699 205 ARG A CA  
1332 C C   . ARG A 206 ? 0.41511 0.37094 0.44264 -0.01538 0.00033  -0.03942 205 ARG A C   
1333 O O   . ARG A 206 ? 0.41306 0.37602 0.45229 -0.02035 -0.00214 -0.03954 205 ARG A O   
1334 C CB  . ARG A 206 ? 0.45823 0.38904 0.48942 -0.01583 -0.00234 -0.04637 205 ARG A CB  
1335 C CG  . ARG A 206 ? 0.51913 0.45009 0.56652 -0.02360 -0.00952 -0.05190 205 ARG A CG  
1336 C CD  . ARG A 206 ? 0.54192 0.45638 0.59026 -0.02409 -0.01687 -0.06163 205 ARG A CD  
1337 N NE  . ARG A 206 ? 0.55392 0.46940 0.62053 -0.03281 -0.02455 -0.06719 205 ARG A NE  
1338 C CZ  . ARG A 206 ? 0.58674 0.49872 0.67340 -0.04236 -0.02276 -0.06334 205 ARG A CZ  
1339 N NH1 . ARG A 206 ? 0.51812 0.42530 0.60788 -0.04377 -0.01322 -0.05332 205 ARG A NH1 
1340 N NH2 . ARG A 206 ? 0.58606 0.50015 0.69051 -0.05058 -0.03070 -0.06926 205 ARG A NH2 
1341 N N   . VAL A 207 ? 0.41370 0.37128 0.42514 -0.00857 -0.00012 -0.04080 206 VAL A N   
1342 C CA  . VAL A 207 ? 0.41176 0.37763 0.41807 -0.00691 -0.00379 -0.04233 206 VAL A CA  
1343 C C   . VAL A 207 ? 0.39223 0.36788 0.40214 -0.00948 0.00082  -0.03451 206 VAL A C   
1344 O O   . VAL A 207 ? 0.45301 0.43456 0.46026 -0.00845 -0.00213 -0.03513 206 VAL A O   
1345 C CB  . VAL A 207 ? 0.44786 0.41274 0.43528 0.00139  -0.00480 -0.04473 206 VAL A CB  
1346 C CG1 . VAL A 207 ? 0.46532 0.42074 0.44658 0.00574  -0.01164 -0.05488 206 VAL A CG1 
1347 C CG2 . VAL A 207 ? 0.48755 0.45396 0.46678 0.00460  0.00322  -0.03755 206 VAL A CG2 
1348 N N   . TYR A 208 ? 0.43580 0.41259 0.45051 -0.01189 0.00753  -0.02751 207 TYR A N   
1349 C CA  . TYR A 208 ? 0.37257 0.35742 0.39159 -0.01425 0.01096  -0.02136 207 TYR A CA  
1350 C C   . TYR A 208 ? 0.39639 0.38409 0.43131 -0.01943 0.01210  -0.01950 207 TYR A C   
1351 O O   . TYR A 208 ? 0.40284 0.39727 0.44112 -0.02036 0.01527  -0.01461 207 TYR A O   
1352 C CB  . TYR A 208 ? 0.38302 0.36930 0.39569 -0.01267 0.01718  -0.01477 207 TYR A CB  
1353 C CG  . TYR A 208 ? 0.37593 0.36391 0.37559 -0.00900 0.01747  -0.01370 207 TYR A CG  
1354 C CD1 . TYR A 208 ? 0.39863 0.38320 0.38924 -0.00468 0.01718  -0.01614 207 TYR A CD1 
1355 C CD2 . TYR A 208 ? 0.32344 0.31604 0.31993 -0.00966 0.01837  -0.00988 207 TYR A CD2 
1356 C CE1 . TYR A 208 ? 0.40238 0.39010 0.38220 -0.00152 0.01867  -0.01365 207 TYR A CE1 
1357 C CE2 . TYR A 208 ? 0.38036 0.37398 0.36660 -0.00753 0.01918  -0.00768 207 TYR A CE2 
1358 C CZ  . TYR A 208 ? 0.39814 0.39031 0.37675 -0.00370 0.01982  -0.00898 207 TYR A CZ  
1359 O OH  . TYR A 208 ? 0.37679 0.37154 0.34650 -0.00182 0.02175  -0.00542 207 TYR A OH  
1360 N N   . SER A 209 ? 0.38053 0.36302 0.42540 -0.02271 0.00971  -0.02313 208 SER A N   
1361 C CA  . SER A 209 ? 0.38728 0.37267 0.44887 -0.02834 0.01234  -0.01954 208 SER A CA  
1362 C C   . SER A 209 ? 0.39185 0.38671 0.46474 -0.03130 0.00746  -0.02270 208 SER A C   
1363 O O   . SER A 209 ? 0.42790 0.42375 0.49639 -0.02932 0.00043  -0.02951 208 SER A O   
1364 C CB  . SER A 209 ? 0.39953 0.37348 0.46805 -0.03146 0.01252  -0.02085 208 SER A CB  
1365 O OG  . SER A 209 ? 0.40646 0.37553 0.47932 -0.03353 0.00430  -0.02986 208 SER A OG  
1366 N N   . PRO A 210 ? 0.40908 0.41247 0.49610 -0.03504 0.01126  -0.01750 209 PRO A N   
1367 C CA  . PRO A 210 ? 0.40212 0.41821 0.49918 -0.03616 0.00759  -0.01937 209 PRO A CA  
1368 C C   . PRO A 210 ? 0.40771 0.42523 0.52231 -0.04246 0.00157  -0.02483 209 PRO A C   
1369 O O   . PRO A 210 ? 0.42540 0.43350 0.54747 -0.04739 0.00211  -0.02512 209 PRO A O   
1370 C CB  . PRO A 210 ? 0.38715 0.41259 0.49065 -0.03619 0.01560  -0.01054 209 PRO A CB  
1371 C CG  . PRO A 210 ? 0.44909 0.46669 0.55651 -0.03925 0.02204  -0.00489 209 PRO A CG  
1372 C CD  . PRO A 210 ? 0.40800 0.41151 0.50054 -0.03670 0.01986  -0.00874 209 PRO A CD  
1373 N N   . PRO A 211 ? 0.40227 0.43132 0.52454 -0.04253 -0.00466 -0.02931 210 PRO A N   
1374 C CA  . PRO A 211 ? 0.40872 0.44075 0.54931 -0.04911 -0.01213 -0.03572 210 PRO A CA  
1375 C C   . PRO A 211 ? 0.46888 0.50371 0.63222 -0.05809 -0.00699 -0.02984 210 PRO A C   
1376 O O   . PRO A 211 ? 0.48891 0.51770 0.66536 -0.06520 -0.01212 -0.03461 210 PRO A O   
1377 C CB  . PRO A 211 ? 0.42572 0.47405 0.57089 -0.04613 -0.01809 -0.03930 210 PRO A CB  
1378 C CG  . PRO A 211 ? 0.44203 0.49050 0.56650 -0.03712 -0.01497 -0.03630 210 PRO A CG  
1379 C CD  . PRO A 211 ? 0.40396 0.44418 0.51982 -0.03658 -0.00523 -0.02840 210 PRO A CD  
1380 N N   . GLU A 212 ? 0.43903 0.48267 0.60759 -0.05790 0.00281  -0.01958 211 GLU A N   
1381 C CA  . GLU A 212 ? 0.42669 0.47337 0.61673 -0.06616 0.00893  -0.01235 211 GLU A CA  
1382 C C   . GLU A 212 ? 0.49319 0.51982 0.67897 -0.06920 0.01214  -0.01033 211 GLU A C   
1383 O O   . GLU A 212 ? 0.47432 0.49731 0.67832 -0.07772 0.01396  -0.00719 211 GLU A O   
1384 C CB  . GLU A 212 ? 0.40898 0.47032 0.60315 -0.06333 0.01928  -0.00147 211 GLU A CB  
1385 C CG  . GLU A 212 ? 0.38039 0.43462 0.55285 -0.05549 0.02694  0.00449  211 GLU A CG  
1386 C CD  . GLU A 212 ? 0.42190 0.47869 0.57489 -0.04654 0.02366  0.00044  211 GLU A CD  
1387 O OE1 . GLU A 212 ? 0.36668 0.42553 0.51753 -0.04534 0.01498  -0.00772 211 GLU A OE1 
1388 O OE2 . GLU A 212 ? 0.47777 0.53401 0.61737 -0.04058 0.02957  0.00558  211 GLU A OE2 
1389 N N   . TRP A 213 ? 0.46419 0.47776 0.62692 -0.06235 0.01293  -0.01172 212 TRP A N   
1390 C CA  . TRP A 213 ? 0.49333 0.48746 0.65069 -0.06366 0.01442  -0.01150 212 TRP A CA  
1391 C C   . TRP A 213 ? 0.48032 0.46310 0.64180 -0.06773 0.00393  -0.02263 212 TRP A C   
1392 O O   . TRP A 213 ? 0.48825 0.45903 0.66120 -0.07442 0.00360  -0.02248 212 TRP A O   
1393 C CB  . TRP A 213 ? 0.40361 0.38963 0.53662 -0.05477 0.01780  -0.01020 212 TRP A CB  
1394 C CG  . TRP A 213 ? 0.47966 0.44597 0.60549 -0.05427 0.01703  -0.01268 212 TRP A CG  
1395 C CD1 . TRP A 213 ? 0.43091 0.38668 0.54196 -0.04955 0.01080  -0.02139 212 TRP A CD1 
1396 C CD2 . TRP A 213 ? 0.48708 0.44153 0.61994 -0.05776 0.02280  -0.00623 212 TRP A CD2 
1397 N NE1 . TRP A 213 ? 0.45843 0.39666 0.56655 -0.04931 0.01213  -0.02136 212 TRP A NE1 
1398 C CE2 . TRP A 213 ? 0.47129 0.40745 0.59272 -0.05456 0.01919  -0.01215 212 TRP A CE2 
1399 C CE3 . TRP A 213 ? 0.42978 0.38709 0.57644 -0.06239 0.03116  0.00458  212 TRP A CE3 
1400 C CZ2 . TRP A 213 ? 0.52603 0.44533 0.64924 -0.05576 0.02320  -0.00791 212 TRP A CZ2 
1401 C CZ3 . TRP A 213 ? 0.50652 0.44708 0.65525 -0.06421 0.03552  0.00959  212 TRP A CZ3 
1402 C CH2 . TRP A 213 ? 0.50314 0.42423 0.64025 -0.06094 0.03121  0.00310  212 TRP A CH2 
1403 N N   . ILE A 214 ? 0.47664 0.46195 0.62790 -0.06329 -0.00496 -0.03243 213 ILE A N   
1404 C CA  . ILE A 214 ? 0.47538 0.45053 0.62763 -0.06535 -0.01618 -0.04448 213 ILE A CA  
1405 C C   . ILE A 214 ? 0.53708 0.51625 0.71701 -0.07672 -0.02076 -0.04643 213 ILE A C   
1406 O O   . ILE A 214 ? 0.57035 0.53425 0.75709 -0.08221 -0.02603 -0.05205 213 ILE A O   
1407 C CB  . ILE A 214 ? 0.49193 0.47321 0.62944 -0.05793 -0.02451 -0.05336 213 ILE A CB  
1408 C CG1 . ILE A 214 ? 0.45687 0.43447 0.56873 -0.04782 -0.01968 -0.05065 213 ILE A CG1 
1409 C CG2 . ILE A 214 ? 0.50589 0.47783 0.64413 -0.05923 -0.03726 -0.06686 213 ILE A CG2 
1410 C CD1 . ILE A 214 ? 0.51677 0.47643 0.61469 -0.04418 -0.01733 -0.05144 213 ILE A CD1 
1411 N N   . ARG A 215 ? 0.45500 0.45487 0.65198 -0.08041 -0.01891 -0.04182 214 ARG A N   
1412 C CA  . ARG A 215 ? 0.51066 0.51920 0.73632 -0.09140 -0.02450 -0.04441 214 ARG A CA  
1413 C C   . ARG A 215 ? 0.51638 0.52122 0.76239 -0.10124 -0.01561 -0.03377 214 ARG A C   
1414 O O   . ARG A 215 ? 0.49922 0.49657 0.76439 -0.11162 -0.02084 -0.03726 214 ARG A O   
1415 C CB  . ARG A 215 ? 0.51952 0.55426 0.75590 -0.09025 -0.02654 -0.04409 214 ARG A CB  
1416 C CG  . ARG A 215 ? 0.56442 0.60326 0.78653 -0.08257 -0.03799 -0.05580 214 ARG A CG  
1417 C CD  . ARG A 215 ? 0.63895 0.70301 0.86890 -0.07924 -0.03854 -0.05390 214 ARG A CD  
1418 N NE  . ARG A 215 ? 0.74708 0.82791 1.00752 -0.08846 -0.04478 -0.05670 214 ARG A NE  
1419 C CZ  . ARG A 215 ? 0.86077 0.95183 1.12673 -0.08759 -0.05777 -0.06751 214 ARG A CZ  
1420 N NH2 . ARG A 215 ? 0.77125 0.85641 1.01200 -0.07695 -0.06497 -0.07571 214 ARG A NH2 
1421 N N   . TYR A 216 ? 0.46984 0.47967 0.71231 -0.09823 -0.00244 -0.02066 215 TYR A N   
1422 C CA  . TYR A 216 ? 0.51901 0.52990 0.78153 -0.10657 0.00739  -0.00845 215 TYR A CA  
1423 C C   . TYR A 216 ? 0.46509 0.45732 0.71343 -0.10321 0.01706  0.00006  215 TYR A C   
1424 O O   . TYR A 216 ? 0.51686 0.50640 0.77979 -0.10962 0.02552  0.01084  215 TYR A O   
1425 C CB  . TYR A 216 ? 0.46418 0.50171 0.73929 -0.10592 0.01549  0.00136  215 TYR A CB  
1426 C CG  . TYR A 216 ? 0.53037 0.58883 0.81717 -0.10660 0.00645  -0.00646 215 TYR A CG  
1427 C CD1 . TYR A 216 ? 0.58982 0.65372 0.90261 -0.11766 -0.00251 -0.01266 215 TYR A CD1 
1428 C CD2 . TYR A 216 ? 0.54279 0.61514 0.81482 -0.09602 0.00629  -0.00785 215 TYR A CD2 
1429 C CE1 . TYR A 216 ? 0.62404 0.70875 0.94779 -0.11742 -0.01148 -0.02005 215 TYR A CE1 
1430 C CE2 . TYR A 216 ? 0.60117 0.69231 0.88285 -0.09529 -0.00205 -0.01468 215 TYR A CE2 
1431 C CZ  . TYR A 216 ? 0.65397 0.75229 0.96149 -0.10562 -0.01094 -0.02075 215 TYR A CZ  
1432 O OH  . TYR A 216 ? 0.75387 0.87253 1.07121 -0.10406 -0.01987 -0.02774 215 TYR A OH  
1433 N N   . HIS A 217 ? 0.49560 0.47607 0.71665 -0.09312 0.01638  -0.00372 216 HIS A N   
1434 C CA  . HIS A 217 ? 0.50620 0.47174 0.71232 -0.08805 0.02515  0.00411  216 HIS A CA  
1435 C C   . HIS A 217 ? 0.50659 0.48499 0.71550 -0.08594 0.03803  0.01862  216 HIS A C   
1436 O O   . HIS A 217 ? 0.44538 0.41414 0.65438 -0.08628 0.04662  0.02848  216 HIS A O   
1437 C CB  . HIS A 217 ? 0.55276 0.49466 0.76535 -0.09432 0.02371  0.00332  216 HIS A CB  
1438 C CG  . HIS A 217 ? 0.69204 0.61553 0.88794 -0.08978 0.01400  -0.00958 216 HIS A CG  
1439 N ND1 . HIS A 217 ? 0.80549 0.70379 0.99663 -0.09013 0.01329  -0.01103 216 HIS A ND1 
1440 C CD2 . HIS A 217 ? 0.67082 0.59742 0.85240 -0.08360 0.00508  -0.02123 216 HIS A CD2 
1441 C CE1 . HIS A 217 ? 0.82584 0.71344 1.00031 -0.08392 0.00430  -0.02354 216 HIS A CE1 
1442 N NE2 . HIS A 217 ? 0.78795 0.69278 0.95639 -0.08003 -0.00054 -0.02952 216 HIS A NE2 
1443 N N   . ARG A 218 ? 0.46071 0.46051 0.67047 -0.08260 0.03917  0.01976  217 ARG A N   
1444 C CA  . ARG A 218 ? 0.46312 0.47752 0.67338 -0.07865 0.05025  0.03175  217 ARG A CA  
1445 C C   . ARG A 218 ? 0.46261 0.48925 0.65638 -0.06922 0.04842  0.02804  217 ARG A C   
1446 O O   . ARG A 218 ? 0.40684 0.44111 0.60215 -0.06923 0.04004  0.01919  217 ARG A O   
1447 C CB  . ARG A 218 ? 0.49532 0.52665 0.73338 -0.08689 0.05470  0.03896  217 ARG A CB  
1448 C CG  . ARG A 218 ? 0.49960 0.52063 0.75584 -0.09655 0.06032  0.04744  217 ARG A CG  
1449 C CD  . ARG A 218 ? 0.56506 0.60513 0.85302 -0.10681 0.06218  0.05229  217 ARG A CD  
1450 N NE  . ARG A 218 ? 0.57722 0.64034 0.86832 -0.10145 0.07280  0.06320  217 ARG A NE  
1451 C CZ  . ARG A 218 ? 0.68025 0.74629 0.97691 -0.10150 0.08610  0.07839  217 ARG A CZ  
1452 N NH1 . ARG A 218 ? 0.69015 0.73675 0.99005 -0.10692 0.09080  0.08536  217 ARG A NH1 
1453 N NH2 . ARG A 218 ? 0.64006 0.72839 0.93789 -0.09502 0.09506  0.08700  217 ARG A NH2 
1454 N N   . TYR A 219 ? 0.42285 0.45081 0.60081 -0.06103 0.05580  0.03474  218 TYR A N   
1455 C CA  . TYR A 219 ? 0.38955 0.42728 0.55226 -0.05257 0.05425  0.03175  218 TYR A CA  
1456 C C   . TYR A 219 ? 0.45906 0.50238 0.61303 -0.04571 0.06409  0.04168  218 TYR A C   
1457 O O   . TYR A 219 ? 0.41974 0.45607 0.57344 -0.04581 0.07120  0.04979  218 TYR A O   
1458 C CB  . TYR A 219 ? 0.35978 0.38591 0.50255 -0.04814 0.04694  0.02270  218 TYR A CB  
1459 C CG  . TYR A 219 ? 0.41853 0.42965 0.54767 -0.04506 0.05024  0.02545  218 TYR A CG  
1460 C CD1 . TYR A 219 ? 0.42445 0.42025 0.55714 -0.04929 0.04843  0.02354  218 TYR A CD1 
1461 C CD2 . TYR A 219 ? 0.41218 0.42455 0.52518 -0.03746 0.05471  0.02966  218 TYR A CD2 
1462 C CE1 . TYR A 219 ? 0.41964 0.40246 0.53979 -0.04514 0.05162  0.02632  218 TYR A CE1 
1463 C CE2 . TYR A 219 ? 0.38916 0.39014 0.49076 -0.03402 0.05736  0.03223  218 TYR A CE2 
1464 C CZ  . TYR A 219 ? 0.46005 0.44669 0.56518 -0.03746 0.05613  0.03084  218 TYR A CZ  
1465 O OH  . TYR A 219 ? 0.41477 0.39071 0.50862 -0.03282 0.05889  0.03361  218 TYR A OH  
1466 N N   . HIS A 220 ? 0.38730 0.44240 0.53301 -0.03897 0.06406  0.04076  219 HIS A N   
1467 C CA  . HIS A 220 ? 0.33501 0.39372 0.46704 -0.03047 0.07098  0.04726  219 HIS A CA  
1468 C C   . HIS A 220 ? 0.36818 0.41856 0.47802 -0.02440 0.06591  0.04110  219 HIS A C   
1469 O O   . HIS A 220 ? 0.35126 0.39859 0.45665 -0.02521 0.05795  0.03258  219 HIS A O   
1470 C CB  . HIS A 220 ? 0.35297 0.43014 0.49119 -0.02637 0.07516  0.05106  219 HIS A CB  
1471 C CG  . HIS A 220 ? 0.36657 0.45424 0.52711 -0.03186 0.08272  0.06005  219 HIS A CG  
1472 N ND1 . HIS A 220 ? 0.42529 0.51926 0.60831 -0.04104 0.07912  0.05761  219 HIS A ND1 
1473 C CD2 . HIS A 220 ? 0.38566 0.47821 0.55012 -0.03000 0.09369  0.07195  219 HIS A CD2 
1474 C CE1 . HIS A 220 ? 0.39432 0.49741 0.59609 -0.04557 0.08778  0.06792  219 HIS A CE1 
1475 N NE2 . HIS A 220 ? 0.43310 0.53526 0.62344 -0.03869 0.09730  0.07731  219 HIS A NE2 
1476 N N   . GLY A 221 ? 0.40913 0.45634 0.50550 -0.01833 0.07059  0.04593  220 GLY A N   
1477 C CA  . GLY A 221 ? 0.39495 0.43315 0.47365 -0.01468 0.06606  0.04110  220 GLY A CA  
1478 C C   . GLY A 221 ? 0.37143 0.41258 0.44051 -0.01153 0.05974  0.03401  220 GLY A C   
1479 O O   . GLY A 221 ? 0.37535 0.40969 0.43818 -0.01305 0.05350  0.02766  220 GLY A O   
1480 N N   . ARG A 222 ? 0.36058 0.41123 0.42734 -0.00635 0.06166  0.03545  221 ARG A N   
1481 C CA  . ARG A 222 ? 0.40472 0.45496 0.45952 -0.00223 0.05588  0.02931  221 ARG A CA  
1482 C C   . ARG A 222 ? 0.36098 0.41146 0.42166 -0.00590 0.04951  0.02300  221 ARG A C   
1483 O O   . ARG A 222 ? 0.37726 0.42094 0.42811 -0.00563 0.04353  0.01752  221 ARG A O   
1484 C CB  . ARG A 222 ? 0.38871 0.44754 0.43794 0.00575  0.05929  0.03183  221 ARG A CB  
1485 C CG  . ARG A 222 ? 0.50692 0.56474 0.54517 0.01152  0.06396  0.03666  221 ARG A CG  
1486 C CD  . ARG A 222 ? 0.52395 0.59001 0.55464 0.02099  0.06708  0.03840  221 ARG A CD  
1487 N NE  . ARG A 222 ? 0.64426 0.71134 0.66550 0.02736  0.07236  0.04394  221 ARG A NE  
1488 C CZ  . ARG A 222 ? 0.61867 0.69230 0.64701 0.02857  0.08135  0.05320  221 ARG A CZ  
1489 N NH1 . ARG A 222 ? 0.60374 0.68312 0.65096 0.02221  0.08601  0.05804  221 ARG A NH1 
1490 N NH2 . ARG A 222 ? 0.65683 0.73129 0.67326 0.03633  0.08559  0.05795  221 ARG A NH2 
1491 N N   . SER A 223 ? 0.34230 0.40127 0.41930 -0.00924 0.05060  0.02400  222 SER A N   
1492 C CA  . SER A 223 ? 0.32808 0.38861 0.41011 -0.01161 0.04365  0.01752  222 SER A CA  
1493 C C   . SER A 223 ? 0.37144 0.42120 0.45267 -0.01706 0.03860  0.01288  222 SER A C   
1494 O O   . SER A 223 ? 0.35022 0.39677 0.42606 -0.01669 0.03199  0.00682  222 SER A O   
1495 C CB  . SER A 223 ? 0.32986 0.40478 0.43143 -0.01385 0.04534  0.01940  222 SER A CB  
1496 O OG  . SER A 223 ? 0.41001 0.48649 0.52582 -0.01970 0.05101  0.02528  222 SER A OG  
1497 N N   . ALA A 224 ? 0.35612 0.39957 0.44109 -0.02099 0.04178  0.01580  223 ALA A N   
1498 C CA  . ALA A 224 ? 0.36102 0.39323 0.44191 -0.02408 0.03724  0.01102  223 ALA A CA  
1499 C C   . ALA A 224 ? 0.36839 0.39386 0.43119 -0.02006 0.03511  0.00891  223 ALA A C   
1500 O O   . ALA A 224 ? 0.34355 0.36373 0.40025 -0.02039 0.02988  0.00366  223 ALA A O   
1501 C CB  . ALA A 224 ? 0.34817 0.37348 0.43597 -0.02800 0.04127  0.01477  223 ALA A CB  
1502 N N   . ALA A 225 ? 0.36516 0.39132 0.41944 -0.01618 0.03900  0.01306  224 ALA A N   
1503 C CA  . ALA A 225 ? 0.34655 0.36769 0.38622 -0.01359 0.03651  0.01119  224 ALA A CA  
1504 C C   . ALA A 225 ? 0.37811 0.39939 0.41209 -0.01221 0.03117  0.00672  224 ALA A C   
1505 O O   . ALA A 225 ? 0.34362 0.35936 0.36960 -0.01261 0.02765  0.00392  224 ALA A O   
1506 C CB  . ALA A 225 ? 0.33604 0.35892 0.36854 -0.00962 0.04025  0.01544  224 ALA A CB  
1507 N N   . VAL A 226 ? 0.34592 0.37377 0.38382 -0.00995 0.03097  0.00661  225 VAL A N   
1508 C CA  . VAL A 226 ? 0.31665 0.34378 0.34857 -0.00738 0.02591  0.00276  225 VAL A CA  
1509 C C   . VAL A 226 ? 0.32826 0.35299 0.36220 -0.00984 0.02097  -0.00163 225 VAL A C   
1510 O O   . VAL A 226 ? 0.34676 0.36598 0.37072 -0.00833 0.01699  -0.00408 225 VAL A O   
1511 C CB  . VAL A 226 ? 0.30094 0.33715 0.33782 -0.00318 0.02706  0.00358  225 VAL A CB  
1512 C CG1 . VAL A 226 ? 0.33177 0.36772 0.36459 0.00008  0.02133  -0.00062 225 VAL A CG1 
1513 C CG2 . VAL A 226 ? 0.34092 0.37697 0.36938 0.00162  0.03058  0.00653  225 VAL A CG2 
1514 N N   . TRP A 227 ? 0.33340 0.36163 0.37980 -0.01347 0.02091  -0.00264 226 TRP A N   
1515 C CA  . TRP A 227 ? 0.35587 0.38098 0.40261 -0.01510 0.01533  -0.00794 226 TRP A CA  
1516 C C   . TRP A 227 ? 0.33077 0.34618 0.36476 -0.01482 0.01472  -0.00874 226 TRP A C   
1517 O O   . TRP A 227 ? 0.32021 0.33219 0.34497 -0.01263 0.01065  -0.01164 226 TRP A O   
1518 C CB  . TRP A 227 ? 0.36428 0.39244 0.42684 -0.01999 0.01490  -0.00943 226 TRP A CB  
1519 C CG  . TRP A 227 ? 0.36045 0.38388 0.42153 -0.02097 0.00824  -0.01617 226 TRP A CG  
1520 C CD1 . TRP A 227 ? 0.35762 0.37115 0.41057 -0.02115 0.00744  -0.01836 226 TRP A CD1 
1521 C CD2 . TRP A 227 ? 0.32157 0.35063 0.38827 -0.02057 0.00111  -0.02203 226 TRP A CD2 
1522 N NE1 . TRP A 227 ? 0.33819 0.34986 0.39006 -0.02055 0.00035  -0.02543 226 TRP A NE1 
1523 C CE2 . TRP A 227 ? 0.34918 0.37028 0.40947 -0.02041 -0.00408 -0.02798 226 TRP A CE2 
1524 C CE3 . TRP A 227 ? 0.36540 0.40639 0.44155 -0.01941 -0.00162 -0.02301 226 TRP A CE3 
1525 C CZ2 . TRP A 227 ? 0.35758 0.38168 0.41981 -0.01921 -0.01254 -0.03531 226 TRP A CZ2 
1526 C CZ3 . TRP A 227 ? 0.38546 0.43059 0.46519 -0.01864 -0.01005 -0.02999 226 TRP A CZ3 
1527 C CH2 . TRP A 227 ? 0.36886 0.40523 0.44124 -0.01860 -0.01572 -0.03624 226 TRP A CH2 
1528 N N   . SER A 228 ? 0.36589 0.37776 0.39908 -0.01632 0.01915  -0.00554 227 SER A N   
1529 C CA  . SER A 228 ? 0.39069 0.39607 0.41339 -0.01557 0.01922  -0.00577 227 SER A CA  
1530 C C   . SER A 228 ? 0.30720 0.31122 0.31836 -0.01345 0.01844  -0.00441 227 SER A C   
1531 O O   . SER A 228 ? 0.33030 0.33077 0.33302 -0.01256 0.01722  -0.00509 227 SER A O   
1532 C CB  . SER A 228 ? 0.37180 0.37523 0.39617 -0.01645 0.02418  -0.00209 227 SER A CB  
1533 O OG  . SER A 228 ? 0.37951 0.38585 0.40142 -0.01538 0.02766  0.00247  227 SER A OG  
1534 N N   . LEU A 229 ? 0.34225 0.34859 0.35277 -0.01243 0.01925  -0.00231 228 LEU A N   
1535 C CA  . LEU A 229 ? 0.32614 0.32878 0.32643 -0.01110 0.01772  -0.00138 228 LEU A CA  
1536 C C   . LEU A 229 ? 0.31487 0.31496 0.31011 -0.00898 0.01333  -0.00398 228 LEU A C   
1537 O O   . LEU A 229 ? 0.35445 0.34912 0.34030 -0.00860 0.01216  -0.00285 228 LEU A O   
1538 C CB  . LEU A 229 ? 0.32469 0.32883 0.32452 -0.00953 0.01903  0.00042  228 LEU A CB  
1539 C CG  . LEU A 229 ? 0.34592 0.35170 0.34654 -0.01048 0.02271  0.00338  228 LEU A CG  
1540 C CD1 . LEU A 229 ? 0.36632 0.37537 0.36730 -0.00731 0.02433  0.00458  228 LEU A CD1 
1541 C CD2 . LEU A 229 ? 0.34667 0.34851 0.33975 -0.01232 0.02168  0.00446  228 LEU A CD2 
1542 N N   . GLY A 230 ? 0.31175 0.31629 0.31358 -0.00752 0.01089  -0.00696 229 GLY A N   
1543 C CA  . GLY A 230 ? 0.33475 0.33781 0.33141 -0.00448 0.00605  -0.00984 229 GLY A CA  
1544 C C   . GLY A 230 ? 0.36293 0.36219 0.35332 -0.00458 0.00473  -0.01133 229 GLY A C   
1545 O O   . GLY A 230 ? 0.33674 0.33131 0.31618 -0.00186 0.00289  -0.01072 229 GLY A O   
1546 N N   . ILE A 231 ? 0.31030 0.31081 0.30659 -0.00699 0.00600  -0.01292 230 ILE A N   
1547 C CA  . ILE A 231 ? 0.33798 0.33479 0.32699 -0.00569 0.00519  -0.01472 230 ILE A CA  
1548 C C   . ILE A 231 ? 0.35477 0.34806 0.33334 -0.00539 0.00877  -0.00974 230 ILE A C   
1549 O O   . ILE A 231 ? 0.40669 0.39739 0.37492 -0.00243 0.00798  -0.00930 230 ILE A O   
1550 C CB  . ILE A 231 ? 0.38608 0.38270 0.38290 -0.00794 0.00632  -0.01715 230 ILE A CB  
1551 C CG1 . ILE A 231 ? 0.34349 0.34378 0.35352 -0.00998 0.00264  -0.02160 230 ILE A CG1 
1552 C CG2 . ILE A 231 ? 0.31101 0.30337 0.29825 -0.00477 0.00540  -0.01973 230 ILE A CG2 
1553 C CD1 . ILE A 231 ? 0.29087 0.29230 0.29831 -0.00684 -0.00494 -0.02812 230 ILE A CD1 
1554 N N   . LEU A 232 ? 0.32790 0.32193 0.30945 -0.00837 0.01273  -0.00566 231 LEU A N   
1555 C CA  . LEU A 232 ? 0.31862 0.31123 0.29373 -0.00954 0.01575  -0.00089 231 LEU A CA  
1556 C C   . LEU A 232 ? 0.33982 0.32782 0.30664 -0.00879 0.01406  0.00149  231 LEU A C   
1557 O O   . LEU A 232 ? 0.36945 0.35565 0.32925 -0.00887 0.01571  0.00509  231 LEU A O   
1558 C CB  . LEU A 232 ? 0.30191 0.29700 0.28266 -0.01259 0.01869  0.00185  231 LEU A CB  
1559 C CG  . LEU A 232 ? 0.34998 0.34548 0.32720 -0.01503 0.02079  0.00637  231 LEU A CG  
1560 C CD1 . LEU A 232 ? 0.37745 0.37643 0.35293 -0.01417 0.02371  0.00790  231 LEU A CD1 
1561 C CD2 . LEU A 232 ? 0.31985 0.31802 0.30198 -0.01707 0.02185  0.00767  231 LEU A CD2 
1562 N N   . LEU A 233 ? 0.35982 0.34572 0.32740 -0.00778 0.01127  0.00022  232 LEU A N   
1563 C CA  . LEU A 233 ? 0.34008 0.31895 0.29886 -0.00633 0.00938  0.00252  232 LEU A CA  
1564 C C   . LEU A 233 ? 0.36016 0.33686 0.31030 -0.00203 0.00741  0.00213  232 LEU A C   
1565 O O   . LEU A 233 ? 0.40038 0.37131 0.34134 -0.00161 0.00839  0.00662  232 LEU A O   
1566 C CB  . LEU A 233 ? 0.31170 0.28904 0.27252 -0.00430 0.00675  0.00058  232 LEU A CB  
1567 C CG  . LEU A 233 ? 0.37562 0.34308 0.32655 -0.00175 0.00428  0.00256  232 LEU A CG  
1568 C CD1 . LEU A 233 ? 0.38174 0.34161 0.32782 -0.00651 0.00626  0.00755  232 LEU A CD1 
1569 C CD2 . LEU A 233 ? 0.34397 0.31075 0.29682 0.00165  0.00205  0.00006  232 LEU A CD2 
1570 N N   . TYR A 234 ? 0.38137 0.36256 0.33425 0.00126  0.00438  -0.00304 233 TYR A N   
1571 C CA  . TYR A 234 ? 0.35863 0.33870 0.30207 0.00641  0.00183  -0.00444 233 TYR A CA  
1572 C C   . TYR A 234 ? 0.42588 0.40527 0.36228 0.00619  0.00606  -0.00081 233 TYR A C   
1573 O O   . TYR A 234 ? 0.39924 0.37491 0.32402 0.00948  0.00697  0.00313  233 TYR A O   
1574 C CB  . TYR A 234 ? 0.37223 0.35828 0.32232 0.00874  -0.00296 -0.01194 233 TYR A CB  
1575 C CG  . TYR A 234 ? 0.40472 0.39012 0.34416 0.01532  -0.00732 -0.01499 233 TYR A CG  
1576 C CD1 . TYR A 234 ? 0.38771 0.37209 0.31889 0.01762  -0.00573 -0.01525 233 TYR A CD1 
1577 C CD2 . TYR A 234 ? 0.38579 0.37215 0.32216 0.02057  -0.01305 -0.01757 233 TYR A CD2 
1578 C CE1 . TYR A 234 ? 0.42270 0.40640 0.34142 0.02519  -0.00978 -0.01819 233 TYR A CE1 
1579 C CE2 . TYR A 234 ? 0.40951 0.39564 0.33430 0.02785  -0.01767 -0.02053 233 TYR A CE2 
1580 C CZ  . TYR A 234 ? 0.48042 0.46481 0.39573 0.03015  -0.01592 -0.02081 233 TYR A CZ  
1581 O OH  . TYR A 234 ? 0.44643 0.43056 0.34814 0.03862  -0.02042 -0.02393 233 TYR A OH  
1582 N N   . ASP A 235 ? 0.37453 0.35807 0.31774 0.00309  0.00914  -0.00154 234 ASP A N   
1583 C CA  . ASP A 235 ? 0.39892 0.38422 0.33719 0.00339  0.01390  0.00215  234 ASP A CA  
1584 C C   . ASP A 235 ? 0.38389 0.36674 0.31692 0.00095  0.01775  0.01042  234 ASP A C   
1585 O O   . ASP A 235 ? 0.41165 0.39487 0.33566 0.00380  0.02071  0.01469  234 ASP A O   
1586 C CB  . ASP A 235 ? 0.36277 0.35245 0.31100 0.00000  0.01667  0.00103  234 ASP A CB  
1587 C CG  . ASP A 235 ? 0.44283 0.43644 0.38739 0.00148  0.02160  0.00417  234 ASP A CG  
1588 O OD1 . ASP A 235 ? 0.43613 0.42980 0.37105 0.00721  0.02182  0.00322  234 ASP A OD1 
1589 O OD2 . ASP A 235 ? 0.42382 0.42148 0.37502 -0.00227 0.02517  0.00744  234 ASP A OD2 
1590 N N   . MET A 236 ? 0.40460 0.38471 0.34322 -0.00430 0.01775  0.01289  235 MET A N   
1591 C CA  . MET A 236 ? 0.41774 0.39424 0.35371 -0.00839 0.02059  0.02032  235 MET A CA  
1592 C C   . MET A 236 ? 0.44904 0.41730 0.37328 -0.00487 0.01958  0.02396  235 MET A C   
1593 O O   . MET A 236 ? 0.44136 0.40872 0.35986 -0.00548 0.02364  0.03108  235 MET A O   
1594 C CB  . MET A 236 ? 0.36092 0.33458 0.30449 -0.01405 0.01915  0.02023  235 MET A CB  
1595 C CG  . MET A 236 ? 0.37019 0.35232 0.32372 -0.01790 0.02145  0.01964  235 MET A CG  
1596 S SD  . MET A 236 ? 0.49874 0.47696 0.45789 -0.02362 0.01910  0.01981  235 MET A SD  
1597 C CE  . MET A 236 ? 0.36754 0.34022 0.32491 -0.01912 0.01488  0.01420  235 MET A CE  
1598 N N   . VAL A 237 ? 0.40762 0.37045 0.32831 -0.00071 0.01455  0.01990  236 VAL A N   
1599 C CA  . VAL A 237 ? 0.43101 0.38454 0.33970 0.00343  0.01328  0.02389  236 VAL A CA  
1600 C C   . VAL A 237 ? 0.45922 0.41535 0.35697 0.01148  0.01284  0.02320  236 VAL A C   
1601 O O   . VAL A 237 ? 0.47246 0.42170 0.35802 0.01570  0.01340  0.02856  236 VAL A O   
1602 C CB  . VAL A 237 ? 0.43157 0.37796 0.34006 0.00570  0.00797  0.02047  236 VAL A CB  
1603 C CG1 . VAL A 237 ? 0.44276 0.38463 0.35874 -0.00104 0.00824  0.02125  236 VAL A CG1 
1604 C CG2 . VAL A 237 ? 0.41763 0.37204 0.33153 0.01019  0.00344  0.01189  236 VAL A CG2 
1605 N N   . CYS A 238 ? 0.43534 0.40017 0.33598 0.01418  0.01175  0.01690  237 CYS A N   
1606 C CA  . CYS A 238 ? 0.44463 0.41154 0.33357 0.02270  0.01020  0.01473  237 CYS A CA  
1607 C C   . CYS A 238 ? 0.52411 0.49683 0.40915 0.02405  0.01569  0.01717  237 CYS A C   
1608 O O   . CYS A 238 ? 0.46065 0.43424 0.33253 0.03223  0.01550  0.01691  237 CYS A O   
1609 C CB  . CYS A 238 ? 0.44002 0.41097 0.33318 0.02655  0.00280  0.00412  237 CYS A CB  
1610 S SG  . CYS A 238 ? 0.51384 0.48055 0.40547 0.03043  -0.00400 0.00195  237 CYS A SG  
1611 N N   . GLY A 239 ? 0.45923 0.43665 0.35442 0.01749  0.02042  0.01940  238 GLY A N   
1612 C CA  . GLY A 239 ? 0.47282 0.45724 0.36497 0.01964  0.02613  0.02211  238 GLY A CA  
1613 C C   . GLY A 239 ? 0.46666 0.45566 0.36198 0.02286  0.02397  0.01334  238 GLY A C   
1614 O O   . GLY A 239 ? 0.47266 0.46767 0.36717 0.02468  0.02888  0.01501  238 GLY A O   
1615 N N   . ASP A 240 ? 0.44859 0.43495 0.34825 0.02355  0.01692  0.00434  239 ASP A N   
1616 C CA  . ASP A 240 ? 0.42836 0.41654 0.33380 0.02454  0.01443  -0.00389 239 ASP A CA  
1617 C C   . ASP A 240 ? 0.47849 0.46457 0.39489 0.02096  0.00788  -0.01060 239 ASP A C   
1618 O O   . ASP A 240 ? 0.42755 0.41179 0.34418 0.02034  0.00463  -0.01005 239 ASP A O   
1619 C CB  . ASP A 240 ? 0.45546 0.44352 0.34747 0.03423  0.01250  -0.00908 239 ASP A CB  
1620 C CG  . ASP A 240 ? 0.55345 0.54184 0.44975 0.03537  0.01241  -0.01531 239 ASP A CG  
1621 O OD1 . ASP A 240 ? 0.49859 0.48819 0.40790 0.02886  0.01495  -0.01409 239 ASP A OD1 
1622 O OD2 . ASP A 240 ? 0.58263 0.56914 0.46812 0.04360  0.00951  -0.02161 239 ASP A OD2 
1623 N N   . ILE A 241 ? 0.43558 0.42211 0.36141 0.01888  0.00644  -0.01630 240 ILE A N   
1624 C CA  . ILE A 241 ? 0.40279 0.38912 0.34200 0.01439  0.00175  -0.02135 240 ILE A CA  
1625 C C   . ILE A 241 ? 0.43117 0.41697 0.36712 0.01875  -0.00642 -0.02871 240 ILE A C   
1626 O O   . ILE A 241 ? 0.43874 0.42297 0.36201 0.02575  -0.00898 -0.03212 240 ILE A O   
1627 C CB  . ILE A 241 ? 0.43835 0.42396 0.38796 0.01112  0.00292  -0.02445 240 ILE A CB  
1628 C CG1 . ILE A 241 ? 0.45058 0.43249 0.39238 0.01705  0.00035  -0.03103 240 ILE A CG1 
1629 C CG2 . ILE A 241 ? 0.38980 0.37763 0.34342 0.00736  0.01019  -0.01731 240 ILE A CG2 
1630 C CD1 . ILE A 241 ? 0.47565 0.45401 0.42606 0.01463  0.00162  -0.03369 240 ILE A CD1 
1631 N N   . PRO A 242 ? 0.40374 0.39206 0.35058 0.01562  -0.01083 -0.03143 241 PRO A N   
1632 C CA  . PRO A 242 ? 0.43652 0.42683 0.38157 0.01995  -0.01935 -0.03834 241 PRO A CA  
1633 C C   . PRO A 242 ? 0.48841 0.47813 0.43883 0.02017  -0.02579 -0.04821 241 PRO A C   
1634 O O   . PRO A 242 ? 0.49588 0.48590 0.43860 0.02612  -0.03319 -0.05494 241 PRO A O   
1635 C CB  . PRO A 242 ? 0.40540 0.40071 0.36262 0.01624  -0.02065 -0.03680 241 PRO A CB  
1636 C CG  . PRO A 242 ? 0.39840 0.39411 0.36829 0.00884  -0.01461 -0.03304 241 PRO A CG  
1637 C CD  . PRO A 242 ? 0.42103 0.41201 0.38169 0.00897  -0.00803 -0.02786 241 PRO A CD  
1638 N N   . PHE A 243 ? 0.46929 0.45726 0.43233 0.01405  -0.02364 -0.04941 242 PHE A N   
1639 C CA  . PHE A 243 ? 0.48297 0.46859 0.45476 0.01221  -0.03031 -0.05871 242 PHE A CA  
1640 C C   . PHE A 243 ? 0.50081 0.47781 0.46671 0.01371  -0.02741 -0.06041 242 PHE A C   
1641 O O   . PHE A 243 ? 0.46915 0.44459 0.43633 0.01133  -0.01931 -0.05364 242 PHE A O   
1642 C CB  . PHE A 243 ? 0.45081 0.44092 0.44525 0.00327  -0.03069 -0.05857 242 PHE A CB  
1643 C CG  . PHE A 243 ? 0.44907 0.44907 0.45082 0.00219  -0.03174 -0.05562 242 PHE A CG  
1644 C CD1 . PHE A 243 ? 0.45782 0.46257 0.45290 0.00796  -0.03879 -0.05958 242 PHE A CD1 
1645 C CD2 . PHE A 243 ? 0.41155 0.41614 0.42568 -0.00331 -0.02568 -0.04893 242 PHE A CD2 
1646 C CE1 . PHE A 243 ? 0.45532 0.46906 0.45673 0.00825  -0.03976 -0.05692 242 PHE A CE1 
1647 C CE2 . PHE A 243 ? 0.43749 0.45112 0.45749 -0.00291 -0.02643 -0.04653 242 PHE A CE2 
1648 C CZ  . PHE A 243 ? 0.43873 0.45687 0.45280 0.00284  -0.03343 -0.05051 242 PHE A CZ  
1649 N N   . GLU A 244 ? 0.50687 0.47829 0.46617 0.01833  -0.03465 -0.07008 243 GLU A N   
1650 C CA  . GLU A 244 ? 0.51517 0.47670 0.47010 0.02030  -0.03336 -0.07364 243 GLU A CA  
1651 C C   . GLU A 244 ? 0.56692 0.52114 0.53613 0.01473  -0.04042 -0.08253 243 GLU A C   
1652 O O   . GLU A 244 ? 0.68122 0.62549 0.65079 0.01440  -0.03809 -0.08379 243 GLU A O   
1653 C CB  . GLU A 244 ? 0.59504 0.55305 0.52689 0.03209  -0.03509 -0.07777 243 GLU A CB  
1654 C CG  . GLU A 244 ? 0.61551 0.57946 0.53325 0.03733  -0.02638 -0.06754 243 GLU A CG  
1655 C CD  . GLU A 244 ? 0.60675 0.57043 0.52566 0.03574  -0.01603 -0.05933 243 GLU A CD  
1656 O OE1 . GLU A 244 ? 0.60279 0.55960 0.52655 0.03470  -0.01555 -0.06263 243 GLU A OE1 
1657 O OE2 . GLU A 244 ? 0.63910 0.60929 0.55432 0.03561  -0.00866 -0.04950 243 GLU A OE2 
1658 N N   . HIS A 245 ? 0.57602 0.53491 0.55782 0.01023  -0.04891 -0.08834 244 HIS A N   
1659 C CA  . HIS A 245 ? 0.58051 0.53260 0.57679 0.00429  -0.05721 -0.09774 244 HIS A CA  
1660 C C   . HIS A 245 ? 0.55458 0.51501 0.57691 -0.00725 -0.05663 -0.09385 244 HIS A C   
1661 O O   . HIS A 245 ? 0.52931 0.50269 0.55645 -0.00832 -0.05434 -0.08810 244 HIS A O   
1662 C CB  . HIS A 245 ? 0.62634 0.57759 0.61465 0.01004  -0.07043 -0.11076 244 HIS A CB  
1663 C CG  . HIS A 245 ? 0.70346 0.64868 0.66418 0.02324  -0.07090 -0.11430 244 HIS A CG  
1664 N ND1 . HIS A 245 ? 0.77269 0.70382 0.72243 0.02813  -0.07033 -0.11897 244 HIS A ND1 
1665 C CD2 . HIS A 245 ? 0.77010 0.72167 0.71145 0.03335  -0.07118 -0.11310 244 HIS A CD2 
1666 C CE1 . HIS A 245 ? 0.77888 0.70956 0.70389 0.04093  -0.06992 -0.12052 244 HIS A CE1 
1667 N NE2 . HIS A 245 ? 0.81377 0.75657 0.73337 0.04397  -0.07024 -0.11661 244 HIS A NE2 
1668 N N   . ASP A 246 ? 0.53350 0.48605 0.57247 -0.01544 -0.05879 -0.09702 245 ASP A N   
1669 C CA  . ASP A 246 ? 0.57803 0.53929 0.64331 -0.02667 -0.05740 -0.09251 245 ASP A CA  
1670 C C   . ASP A 246 ? 0.57805 0.55574 0.65318 -0.02783 -0.06497 -0.09608 245 ASP A C   
1671 O O   . ASP A 246 ? 0.52794 0.51929 0.61676 -0.03213 -0.06027 -0.08855 245 ASP A O   
1672 C CB  . ASP A 246 ? 0.52953 0.47854 0.61132 -0.03539 -0.06083 -0.09695 245 ASP A CB  
1673 C CG  . ASP A 246 ? 0.55374 0.48879 0.63102 -0.03554 -0.05137 -0.09029 245 ASP A CG  
1674 O OD1 . ASP A 246 ? 0.53708 0.47424 0.59980 -0.02925 -0.04254 -0.08257 245 ASP A OD1 
1675 O OD2 . ASP A 246 ? 0.58673 0.50847 0.67530 -0.04191 -0.05308 -0.09272 245 ASP A OD2 
1676 N N   . GLU A 247 ? 0.53355 0.51062 0.60126 -0.02298 -0.07698 -0.10782 246 GLU A N   
1677 C CA  . GLU A 247 ? 0.54727 0.54079 0.62409 -0.02293 -0.08548 -0.11208 246 GLU A CA  
1678 C C   . GLU A 247 ? 0.48783 0.49315 0.55370 -0.01609 -0.07936 -0.10359 246 GLU A C   
1679 O O   . GLU A 247 ? 0.50160 0.52268 0.58049 -0.01792 -0.08112 -0.10161 246 GLU A O   
1680 C CB  . GLU A 247 ? 0.59561 0.58521 0.66214 -0.01685 -0.10006 -0.12681 246 GLU A CB  
1681 C CG  . GLU A 247 ? 0.75070 0.72200 0.81838 -0.02015 -0.10617 -0.13652 246 GLU A CG  
1682 C CD  . GLU A 247 ? 0.77121 0.72566 0.81213 -0.01073 -0.10039 -0.13585 246 GLU A CD  
1683 O OE2 . GLU A 247 ? 0.66984 0.61261 0.71401 -0.01497 -0.09229 -0.13055 246 GLU A OE2 
1684 N N   . GLU A 248 ? 0.49753 0.49540 0.53977 -0.00792 -0.07245 -0.09862 247 GLU A N   
1685 C CA  . GLU A 248 ? 0.54516 0.55099 0.57692 -0.00237 -0.06630 -0.08997 247 GLU A CA  
1686 C C   . GLU A 248 ? 0.52112 0.53248 0.56643 -0.00896 -0.05597 -0.07902 247 GLU A C   
1687 O O   . GLU A 248 ? 0.48558 0.50747 0.53326 -0.00739 -0.05405 -0.07408 247 GLU A O   
1688 C CB  . GLU A 248 ? 0.54827 0.54488 0.55321 0.00688  -0.06161 -0.08717 247 GLU A CB  
1689 C CG  . GLU A 248 ? 0.54823 0.54075 0.53529 0.01629  -0.07090 -0.09692 247 GLU A CG  
1690 C CD  . GLU A 248 ? 0.65667 0.64079 0.61865 0.02520  -0.06471 -0.09320 247 GLU A CD  
1691 O OE1 . GLU A 248 ? 0.57830 0.55665 0.53944 0.02264  -0.05535 -0.08667 247 GLU A OE1 
1692 O OE2 . GLU A 248 ? 0.80816 0.79254 0.75126 0.03531  -0.06911 -0.09647 247 GLU A OE2 
1693 N N   . ILE A 249 ? 0.48098 0.48465 0.53330 -0.01504 -0.04920 -0.07508 248 ILE A N   
1694 C CA  . ILE A 249 ? 0.48775 0.49659 0.55169 -0.02038 -0.03954 -0.06492 248 ILE A CA  
1695 C C   . ILE A 249 ? 0.47604 0.49948 0.56286 -0.02611 -0.04218 -0.06479 248 ILE A C   
1696 O O   . ILE A 249 ? 0.41941 0.45316 0.50976 -0.02513 -0.03751 -0.05829 248 ILE A O   
1697 C CB  . ILE A 249 ? 0.46217 0.45991 0.52950 -0.02508 -0.03284 -0.06128 248 ILE A CB  
1698 C CG1 . ILE A 249 ? 0.44873 0.43518 0.49406 -0.01833 -0.02958 -0.06073 248 ILE A CG1 
1699 C CG2 . ILE A 249 ? 0.43745 0.44118 0.51619 -0.02974 -0.02325 -0.05092 248 ILE A CG2 
1700 C CD1 . ILE A 249 ? 0.48915 0.46391 0.53603 -0.02099 -0.02449 -0.05866 248 ILE A CD1 
1701 N N   . ILE A 250 ? 0.42580 0.45079 0.52892 -0.03196 -0.05003 -0.07221 249 ILE A N   
1702 C CA  . ILE A 250 ? 0.49347 0.53479 0.62199 -0.03852 -0.05186 -0.07124 249 ILE A CA  
1703 C C   . ILE A 250 ? 0.50818 0.56390 0.63740 -0.03335 -0.06100 -0.07698 249 ILE A C   
1704 O O   . ILE A 250 ? 0.47728 0.55023 0.62708 -0.03704 -0.06206 -0.07543 249 ILE A O   
1705 C CB  . ILE A 250 ? 0.58402 0.62196 0.73477 -0.04935 -0.05575 -0.07537 249 ILE A CB  
1706 C CG1 . ILE A 250 ? 0.53335 0.56525 0.68068 -0.04823 -0.06974 -0.08927 249 ILE A CG1 
1707 C CG2 . ILE A 250 ? 0.55705 0.57928 0.70590 -0.05333 -0.04661 -0.06915 249 ILE A CG2 
1708 C CD1 . ILE A 250 ? 0.65394 0.68083 0.82394 -0.05960 -0.07559 -0.09485 249 ILE A CD1 
1709 N N   . GLY A 251 ? 0.50242 0.55269 0.60949 -0.02403 -0.06703 -0.08273 250 GLY A N   
1710 C CA  . GLY A 251 ? 0.46929 0.53231 0.57529 -0.01783 -0.07662 -0.08856 250 GLY A CA  
1711 C C   . GLY A 251 ? 0.51821 0.59277 0.62095 -0.01188 -0.07180 -0.08109 250 GLY A C   
1712 O O   . GLY A 251 ? 0.55745 0.64733 0.66828 -0.00864 -0.07852 -0.08422 250 GLY A O   
1713 N N   . GLY A 252 ? 0.46178 0.52899 0.55213 -0.00965 -0.06101 -0.07184 251 GLY A N   
1714 C CA  . GLY A 252 ? 0.60732 0.68322 0.69529 -0.00445 -0.05642 -0.06508 251 GLY A CA  
1715 C C   . GLY A 252 ? 0.66123 0.73471 0.72733 0.00687  -0.06014 -0.06581 251 GLY A C   
1716 O O   . GLY A 252 ? 0.57664 0.65770 0.64198 0.01208  -0.05851 -0.06176 251 GLY A O   
1717 N N   . GLN A 253 ? 0.56345 0.62613 0.61084 0.01167  -0.06463 -0.07032 252 GLN A N   
1718 C CA  . GLN A 253 ? 0.56034 0.61933 0.58540 0.02275  -0.06727 -0.06960 252 GLN A CA  
1719 C C   . GLN A 253 ? 0.53537 0.57811 0.53935 0.02474  -0.05915 -0.06317 252 GLN A C   
1720 O O   . GLN A 253 ? 0.55184 0.58584 0.55163 0.02160  -0.05728 -0.06473 252 GLN A O   
1721 C CB  . GLN A 253 ? 0.55607 0.61809 0.57501 0.02866  -0.07938 -0.07955 252 GLN A CB  
1722 C CG  . GLN A 253 ? 0.62900 0.70962 0.66951 0.02726  -0.08917 -0.08659 252 GLN A CG  
1723 C CD  . GLN A 253 ? 0.72388 0.80720 0.75678 0.03377  -0.10247 -0.09748 252 GLN A CD  
1724 N N   . VAL A 254 ? 0.46789 0.50666 0.45927 0.03001  -0.05455 -0.05599 253 VAL A N   
1725 C CA  . VAL A 254 ? 0.41948 0.44449 0.39345 0.03085  -0.04676 -0.04891 253 VAL A CA  
1726 C C   . VAL A 254 ? 0.42386 0.44320 0.37595 0.04101  -0.04956 -0.04743 253 VAL A C   
1727 O O   . VAL A 254 ? 0.49960 0.51974 0.44680 0.04660  -0.05050 -0.04423 253 VAL A O   
1728 C CB  . VAL A 254 ? 0.49749 0.51999 0.47558 0.02693  -0.03838 -0.04099 253 VAL A CB  
1729 C CG1 . VAL A 254 ? 0.50318 0.51259 0.46518 0.02685  -0.03140 -0.03406 253 VAL A CG1 
1730 C CG2 . VAL A 254 ? 0.45134 0.48003 0.44986 0.01805  -0.03514 -0.04164 253 VAL A CG2 
1731 N N   . PHE A 255 ? 0.44613 0.45936 0.38419 0.04430  -0.05057 -0.04938 254 PHE A N   
1732 C CA  . PHE A 255 ? 0.50392 0.51088 0.41906 0.05427  -0.05147 -0.04631 254 PHE A CA  
1733 C C   . PHE A 255 ? 0.48859 0.48438 0.39226 0.05243  -0.04116 -0.03585 254 PHE A C   
1734 O O   . PHE A 255 ? 0.43081 0.42378 0.33745 0.04650  -0.03554 -0.03441 254 PHE A O   
1735 C CB  . PHE A 255 ? 0.46595 0.47343 0.37067 0.06023  -0.05799 -0.05407 254 PHE A CB  
1736 C CG  . PHE A 255 ? 0.51028 0.51092 0.38899 0.07112  -0.05694 -0.04939 254 PHE A CG  
1737 C CD1 . PHE A 255 ? 0.56719 0.57025 0.43534 0.08115  -0.06322 -0.04984 254 PHE A CD1 
1738 C CD2 . PHE A 255 ? 0.54465 0.53731 0.40980 0.07178  -0.04905 -0.04360 254 PHE A CD2 
1739 C CE1 . PHE A 255 ? 0.55995 0.55608 0.40312 0.09177  -0.06149 -0.04422 254 PHE A CE1 
1740 C CE2 . PHE A 255 ? 0.53000 0.51730 0.37198 0.08161  -0.04670 -0.03767 254 PHE A CE2 
1741 C CZ  . PHE A 255 ? 0.51516 0.50344 0.34546 0.09169  -0.05286 -0.03779 254 PHE A CZ  
1742 N N   . PHE A 256 ? 0.44672 0.43612 0.33796 0.05745  -0.03891 -0.02847 255 PHE A N   
1743 C CA  . PHE A 256 ? 0.48907 0.46780 0.37095 0.05477  -0.02978 -0.01813 255 PHE A CA  
1744 C C   . PHE A 256 ? 0.48658 0.46016 0.34775 0.06224  -0.02796 -0.01409 255 PHE A C   
1745 O O   . PHE A 256 ? 0.52819 0.49980 0.37536 0.07187  -0.03193 -0.01319 255 PHE A O   
1746 C CB  . PHE A 256 ? 0.43316 0.40523 0.31464 0.05446  -0.02775 -0.01180 255 PHE A CB  
1747 C CG  . PHE A 256 ? 0.42820 0.40315 0.32729 0.04602  -0.02552 -0.01276 255 PHE A CG  
1748 C CD1 . PHE A 256 ? 0.47381 0.44343 0.37631 0.03792  -0.01830 -0.00751 255 PHE A CD1 
1749 C CD2 . PHE A 256 ? 0.45761 0.44236 0.37043 0.04641  -0.03053 -0.01888 255 PHE A CD2 
1750 C CE1 . PHE A 256 ? 0.43865 0.41126 0.35550 0.03142  -0.01645 -0.00858 255 PHE A CE1 
1751 C CE2 . PHE A 256 ? 0.44389 0.43210 0.37183 0.03959  -0.02752 -0.01900 255 PHE A CE2 
1752 C CZ  . PHE A 256 ? 0.45953 0.44102 0.38827 0.03259  -0.02064 -0.01401 255 PHE A CZ  
1753 N N   . ARG A 257 ? 0.49885 0.47113 0.35774 0.05871  -0.02165 -0.01125 256 ARG A N   
1754 C CA  . ARG A 257 ? 0.61395 0.58390 0.45404 0.06614  -0.01872 -0.00749 256 ARG A CA  
1755 C C   . ARG A 257 ? 0.56894 0.53032 0.39862 0.06556  -0.01011 0.00599  256 ARG A C   
1756 O O   . ARG A 257 ? 0.63156 0.59132 0.44504 0.07202  -0.00605 0.01166  256 ARG A O   
1757 C CB  . ARG A 257 ? 0.54726 0.52155 0.39033 0.06391  -0.01619 -0.01164 256 ARG A CB  
1758 C CG  . ARG A 257 ? 0.53910 0.51316 0.39517 0.05309  -0.00810 -0.00648 256 ARG A CG  
1759 C CD  . ARG A 257 ? 0.59374 0.57220 0.45471 0.05189  -0.00747 -0.01272 256 ARG A CD  
1760 N NE  . ARG A 257 ? 0.60016 0.58157 0.47521 0.04878  -0.01500 -0.02350 256 ARG A NE  
1761 C CZ  . ARG A 257 ? 0.65028 0.63309 0.53036 0.04808  -0.01696 -0.03098 256 ARG A CZ  
1762 N NH1 . ARG A 257 ? 0.59141 0.57352 0.46260 0.05160  -0.01218 -0.02977 256 ARG A NH1 
1763 N NH2 . ARG A 257 ? 0.55462 0.53945 0.44904 0.04413  -0.02378 -0.03967 256 ARG A NH2 
1764 N N   . GLN A 258 ? 0.51742 0.47322 0.35625 0.05788  -0.00720 0.01125  257 GLN A N   
1765 C CA  . GLN A 258 ? 0.53522 0.48100 0.36690 0.05544  -0.00013 0.02361  257 GLN A CA  
1766 C C   . GLN A 258 ? 0.48499 0.42198 0.31832 0.05525  -0.00361 0.02489  257 GLN A C   
1767 O O   . GLN A 258 ? 0.47898 0.42025 0.32268 0.05493  -0.00965 0.01686  257 GLN A O   
1768 C CB  . GLN A 258 ? 0.54932 0.49617 0.39222 0.04434  0.00753  0.02862  257 GLN A CB  
1769 C CG  . GLN A 258 ? 0.76534 0.72111 0.60696 0.04506  0.01197  0.02816  257 GLN A CG  
1770 C CD  . GLN A 258 ? 0.79979 0.75380 0.63322 0.04425  0.02127  0.04068  257 GLN A CD  
1771 O OE1 . GLN A 258 ? 0.80588 0.75058 0.63614 0.04135  0.02433  0.05003  257 GLN A OE1 
1772 N NE2 . GLN A 258 ? 0.81621 0.77908 0.64671 0.04680  0.02602  0.04123  257 GLN A NE2 
1773 N N   A ARG A 259 ? 0.50178 0.42620 0.32498 0.05561  0.00061  0.03549  258 ARG A N   
1774 N N   B ARG A 259 ? 0.50177 0.42618 0.32491 0.05569  0.00053  0.03543  258 ARG A N   
1775 C CA  A ARG A 259 ? 0.52141 0.43406 0.34483 0.05540  -0.00202 0.03745  258 ARG A CA  
1776 C CA  B ARG A 259 ? 0.52088 0.43381 0.34411 0.05586  -0.00237 0.03708  258 ARG A CA  
1777 C C   A ARG A 259 ? 0.51205 0.42503 0.35303 0.04478  -0.00165 0.03415  258 ARG A C   
1778 C C   B ARG A 259 ? 0.51215 0.42508 0.35284 0.04502  -0.00173 0.03415  258 ARG A C   
1779 O O   A ARG A 259 ? 0.50608 0.41756 0.35362 0.03537  0.00398  0.03880  258 ARG A O   
1780 O O   B ARG A 259 ? 0.50656 0.41776 0.35343 0.03570  0.00401  0.03904  258 ARG A O   
1781 C CB  A ARG A 259 ? 0.51140 0.40787 0.32105 0.05628  0.00316  0.05036  258 ARG A CB  
1782 C CB  B ARG A 259 ? 0.51149 0.40811 0.31999 0.05774  0.00232  0.04973  258 ARG A CB  
1783 C CG  A ARG A 259 ? 0.58018 0.46071 0.39124 0.05363  0.00140  0.05289  258 ARG A CG  
1784 C CG  B ARG A 259 ? 0.52893 0.41078 0.33183 0.06218  -0.00193 0.05113  258 ARG A CG  
1785 C CD  A ARG A 259 ? 0.53670 0.41684 0.34302 0.06447  -0.00673 0.04618  258 ARG A CD  
1786 C CD  B ARG A 259 ? 0.51550 0.38896 0.33115 0.05195  -0.00149 0.05055  258 ARG A CD  
1787 N NE  A ARG A 259 ? 0.54645 0.41455 0.35670 0.06272  -0.00928 0.04526  258 ARG A NE  
1788 N NE  B ARG A 259 ? 0.53678 0.40052 0.34938 0.05811  -0.00729 0.04741  258 ARG A NE  
1789 C CZ  A ARG A 259 ? 0.53298 0.39592 0.33639 0.07294  -0.01504 0.04265  258 ARG A CZ  
1790 C CZ  B ARG A 259 ? 0.59354 0.44660 0.41230 0.05276  -0.00812 0.04655  258 ARG A CZ  
1791 N NH1 A ARG A 259 ? 0.50249 0.37204 0.29586 0.08502  -0.01936 0.04071  258 ARG A NH1 
1792 N NH1 B ARG A 259 ? 0.47428 0.32496 0.30317 0.04046  -0.00424 0.04842  258 ARG A NH1 
1793 N NH2 A ARG A 259 ? 0.53472 0.38574 0.34066 0.07191  -0.01686 0.04172  258 ARG A NH2 
1794 N NH2 B ARG A 259 ? 0.54870 0.39377 0.36283 0.06082  -0.01337 0.04333  258 ARG A NH2 
1795 N N   . VAL A 260 ? 0.48545 0.40166 0.33407 0.04687  -0.00763 0.02633  259 VAL A N   
1796 C CA  . VAL A 260 ? 0.48065 0.39751 0.34382 0.03902  -0.00752 0.02297  259 VAL A CA  
1797 C C   . VAL A 260 ? 0.51845 0.42748 0.37931 0.04454  -0.01214 0.02117  259 VAL A C   
1798 O O   . VAL A 260 ? 0.51315 0.42678 0.36999 0.05395  -0.01734 0.01728  259 VAL A O   
1799 C CB  . VAL A 260 ? 0.45631 0.38969 0.33450 0.03569  -0.00881 0.01449  259 VAL A CB  
1800 C CG1 . VAL A 260 ? 0.41559 0.35031 0.30707 0.02977  -0.00875 0.01136  259 VAL A CG1 
1801 C CG2 . VAL A 260 ? 0.39715 0.33647 0.27677 0.03087  -0.00388 0.01633  259 VAL A CG2 
1802 N N   . SER A 261 ? 0.50167 0.39918 0.36467 0.03943  -0.01074 0.02358  260 SER A N   
1803 C CA  . SER A 261 ? 0.47167 0.35902 0.33015 0.04580  -0.01479 0.02212  260 SER A CA  
1804 C C   . SER A 261 ? 0.48454 0.38788 0.35309 0.05119  -0.01917 0.01324  260 SER A C   
1805 O O   . SER A 261 ? 0.44010 0.35918 0.32178 0.04664  -0.01844 0.00849  260 SER A O   
1806 C CB  . SER A 261 ? 0.49719 0.36980 0.35719 0.03886  -0.01330 0.02426  260 SER A CB  
1807 O OG  . SER A 261 ? 0.50731 0.39105 0.38164 0.03235  -0.01246 0.01884  260 SER A OG  
1808 N N   . SEP A 262 ? 0.53287 0.43224 0.39557 0.06114  -0.02348 0.01160  261 SEP A N   
1809 C CA  . SEP A 262 ? 0.50164 0.41772 0.37490 0.06698  -0.02739 0.00419  261 SEP A CA  
1810 C CB  . SEP A 262 ? 0.52643 0.43575 0.38941 0.07993  -0.03194 0.00417  261 SEP A CB  
1811 O OG  . SEP A 262 ? 0.60703 0.51354 0.45751 0.08697  -0.03444 0.00719  261 SEP A OG  
1812 C C   . SEP A 262 ? 0.47581 0.39843 0.36293 0.06075  -0.02509 0.00052  261 SEP A C   
1813 O O   . SEP A 262 ? 0.44367 0.38493 0.34521 0.05971  -0.02553 -0.00447 261 SEP A O   
1814 P P   . SEP A 262 ? 0.64925 0.52834 0.47883 0.09166  -0.03342 0.01585  261 SEP A P   
1815 O O1P . SEP A 262 ? 0.51251 0.39174 0.32769 0.10086  -0.03578 0.01955  261 SEP A O1P 
1816 O O2P . SEP A 262 ? 0.53433 0.39676 0.36277 0.07833  -0.02712 0.02220  261 SEP A O2P 
1817 O O3P . SEP A 262 ? 0.57393 0.44289 0.39830 0.10165  -0.03682 0.01422  261 SEP A O3P 
1818 N N   . GLU A 263 ? 0.47422 0.38126 0.35683 0.05664  -0.02283 0.00313  262 GLU A N   
1819 C CA  . GLU A 263 ? 0.48431 0.39655 0.37729 0.05187  -0.02081 -0.00018 262 GLU A CA  
1820 C C   . GLU A 263 ? 0.44030 0.36541 0.34568 0.04173  -0.01711 -0.00072 262 GLU A C   
1821 O O   . GLU A 263 ? 0.45061 0.38977 0.36846 0.03995  -0.01575 -0.00429 262 GLU A O   
1822 C CB  . GLU A 263 ? 0.48025 0.37138 0.36419 0.04974  -0.02059 0.00187  262 GLU A CB  
1823 C CG  . GLU A 263 ? 0.68010 0.55401 0.54970 0.06016  -0.02436 0.00266  262 GLU A CG  
1824 C CD  . GLU A 263 ? 0.74486 0.59907 0.60066 0.05937  -0.02459 0.00975  262 GLU A CD  
1825 O OE2 . GLU A 263 ? 0.58995 0.45008 0.44334 0.06091  -0.02415 0.01286  262 GLU A OE2 
1826 N N   . CYS A 264 ? 0.45763 0.37798 0.35924 0.03574  -0.01502 0.00344  263 CYS A N   
1827 C CA  . CYS A 264 ? 0.42635 0.35812 0.33828 0.02760  -0.01161 0.00293  263 CYS A CA  
1828 C C   . CYS A 264 ? 0.46942 0.41831 0.39018 0.03013  -0.01321 -0.00155 263 CYS A C   
1829 O O   . CYS A 264 ? 0.40278 0.36334 0.33615 0.02577  -0.01146 -0.00441 263 CYS A O   
1830 C CB  . CYS A 264 ? 0.44266 0.36655 0.34815 0.02188  -0.00857 0.00882  263 CYS A CB  
1831 S SG  . CYS A 264 ? 0.48429 0.42055 0.40121 0.01296  -0.00405 0.00849  263 CYS A SG  
1832 N N   . GLN A 265 ? 0.39170 0.34172 0.30592 0.03715  -0.01693 -0.00222 264 GLN A N   
1833 C CA  . GLN A 265 ? 0.41711 0.38337 0.34062 0.03967  -0.02028 -0.00779 264 GLN A CA  
1834 C C   . GLN A 265 ? 0.41145 0.39044 0.34991 0.04021  -0.02102 -0.01202 264 GLN A C   
1835 O O   . GLN A 265 ? 0.41796 0.41034 0.37051 0.03629  -0.02099 -0.01563 264 GLN A O   
1836 C CB  . GLN A 265 ? 0.40293 0.36858 0.31601 0.04910  -0.02557 -0.00845 264 GLN A CB  
1837 C CG  . GLN A 265 ? 0.46983 0.42772 0.36886 0.04992  -0.02473 -0.00464 264 GLN A CG  
1838 C CD  . GLN A 265 ? 0.50644 0.46853 0.39687 0.06002  -0.03093 -0.00716 264 GLN A CD  
1839 O OE1 . GLN A 265 ? 0.53725 0.51122 0.43577 0.06486  -0.03651 -0.01298 264 GLN A OE1 
1840 N NE2 . GLN A 265 ? 0.47163 0.42548 0.34604 0.06351  -0.02993 -0.00259 264 GLN A NE2 
1841 N N   . HIS A 266 ? 0.39718 0.37177 0.33254 0.04545  -0.02147 -0.01132 265 HIS A N   
1842 C CA  . HIS A 266 ? 0.42318 0.41159 0.37198 0.04759  -0.02129 -0.01444 265 HIS A CA  
1843 C C   . HIS A 266 ? 0.38694 0.38054 0.34696 0.03916  -0.01605 -0.01413 265 HIS A C   
1844 O O   . HIS A 266 ? 0.38422 0.39353 0.35999 0.03670  -0.01508 -0.01632 265 HIS A O   
1845 C CB  . HIS A 266 ? 0.41807 0.39879 0.35832 0.05641  -0.02236 -0.01372 265 HIS A CB  
1846 C CG  . HIS A 266 ? 0.43564 0.43105 0.38823 0.05989  -0.02089 -0.01601 265 HIS A CG  
1847 N ND1 . HIS A 266 ? 0.48090 0.47582 0.43697 0.05649  -0.01616 -0.01524 265 HIS A ND1 
1848 C CD2 . HIS A 266 ? 0.50667 0.51948 0.46946 0.06683  -0.02320 -0.01863 265 HIS A CD2 
1849 C CE1 . HIS A 266 ? 0.45955 0.47033 0.42637 0.06159  -0.01482 -0.01669 265 HIS A CE1 
1850 N NE2 . HIS A 266 ? 0.44917 0.47171 0.42139 0.06748  -0.01889 -0.01861 265 HIS A NE2 
1851 N N   . LEU A 267 ? 0.39716 0.37782 0.34972 0.03451  -0.01278 -0.01107 266 LEU A N   
1852 C CA  . LEU A 267 ? 0.36919 0.35425 0.33043 0.02758  -0.00813 -0.01049 266 LEU A CA  
1853 C C   . LEU A 267 ? 0.34690 0.34139 0.31861 0.02129  -0.00688 -0.01141 266 LEU A C   
1854 O O   . LEU A 267 ? 0.36247 0.36779 0.34715 0.01824  -0.00420 -0.01214 266 LEU A O   
1855 C CB  . LEU A 267 ? 0.34945 0.31955 0.30082 0.02349  -0.00627 -0.00753 266 LEU A CB  
1856 C CG  . LEU A 267 ? 0.41473 0.38886 0.37303 0.01720  -0.00208 -0.00678 266 LEU A CG  
1857 C CD1 . LEU A 267 ? 0.34032 0.32480 0.30651 0.02078  0.00003  -0.00827 266 LEU A CD1 
1858 C CD2 . LEU A 267 ? 0.39706 0.35738 0.34627 0.01328  -0.00184 -0.00454 266 LEU A CD2 
1859 N N   . ILE A 268 ? 0.38139 0.37068 0.34662 0.01964  -0.00842 -0.01100 267 ILE A N   
1860 C CA  . ILE A 268 ? 0.34607 0.34214 0.31885 0.01510  -0.00806 -0.01291 267 ILE A CA  
1861 C C   . ILE A 268 ? 0.37714 0.38721 0.36389 0.01631  -0.01102 -0.01735 267 ILE A C   
1862 O O   . ILE A 268 ? 0.34969 0.36714 0.34929 0.01129  -0.00903 -0.01849 267 ILE A O   
1863 C CB  . ILE A 268 ? 0.37508 0.36407 0.33615 0.01599  -0.00971 -0.01216 267 ILE A CB  
1864 C CG1 . ILE A 268 ? 0.38865 0.36692 0.34082 0.01224  -0.00553 -0.00687 267 ILE A CG1 
1865 C CG2 . ILE A 268 ? 0.36938 0.36520 0.33661 0.01394  -0.01120 -0.01620 267 ILE A CG2 
1866 C CD1 . ILE A 268 ? 0.36927 0.34046 0.30841 0.01415  -0.00581 -0.00400 267 ILE A CD1 
1867 N N   . ARG A 269 ? 0.36991 0.38400 0.35513 0.02290  -0.01598 -0.01964 268 ARG A N   
1868 C CA  . ARG A 269 ? 0.39879 0.42842 0.39951 0.02338  -0.01977 -0.02419 268 ARG A CA  
1869 C C   . ARG A 269 ? 0.40155 0.44242 0.41810 0.02118  -0.01574 -0.02295 268 ARG A C   
1870 O O   . ARG A 269 ? 0.37103 0.42451 0.40489 0.01715  -0.01638 -0.02518 268 ARG A O   
1871 C CB  . ARG A 269 ? 0.41500 0.44839 0.41070 0.03209  -0.02635 -0.02678 268 ARG A CB  
1872 C CG  . ARG A 269 ? 0.36828 0.39525 0.35134 0.03480  -0.03124 -0.02895 268 ARG A CG  
1873 C CD  . ARG A 269 ? 0.52124 0.55714 0.50414 0.04315  -0.03912 -0.03309 268 ARG A CD  
1874 N NE  . ARG A 269 ? 0.63444 0.66525 0.60438 0.04669  -0.04404 -0.03557 268 ARG A NE  
1875 C CZ  . ARG A 269 ? 0.60407 0.62279 0.55366 0.05372  -0.04445 -0.03189 268 ARG A CZ  
1876 N NH1 . ARG A 269 ? 0.49918 0.50828 0.43977 0.05740  -0.04120 -0.02625 268 ARG A NH1 
1877 N NH2 . ARG A 269 ? 0.55454 0.56988 0.49189 0.05748  -0.04815 -0.03376 268 ARG A NH2 
1878 N N   . TRP A 270 ? 0.36667 0.40282 0.37732 0.02391  -0.01163 -0.01934 269 TRP A N   
1879 C CA  . TRP A 270 ? 0.35254 0.39893 0.37523 0.02325  -0.00664 -0.01729 269 TRP A CA  
1880 C C   . TRP A 270 ? 0.36625 0.41243 0.39644 0.01489  -0.00143 -0.01512 269 TRP A C   
1881 O O   . TRP A 270 ? 0.33321 0.39150 0.37983 0.01147  0.00135  -0.01426 269 TRP A O   
1882 C CB  . TRP A 270 ? 0.33515 0.37410 0.34576 0.02993  -0.00461 -0.01509 269 TRP A CB  
1883 C CG  . TRP A 270 ? 0.32134 0.37238 0.34099 0.03356  -0.00019 -0.01340 269 TRP A CG  
1884 C CD1 . TRP A 270 ? 0.36527 0.43523 0.40445 0.03168  0.00237  -0.01266 269 TRP A CD1 
1885 C CD2 . TRP A 270 ? 0.38293 0.42809 0.39210 0.04015  0.00240  -0.01202 269 TRP A CD2 
1886 N NE1 . TRP A 270 ? 0.38015 0.45774 0.42136 0.03722  0.00748  -0.00995 269 TRP A NE1 
1887 C CE2 . TRP A 270 ? 0.36647 0.42871 0.38841 0.04312  0.00722  -0.01015 269 TRP A CE2 
1888 C CE3 . TRP A 270 ? 0.41532 0.44194 0.40572 0.04361  0.00094  -0.01225 269 TRP A CE3 
1889 C CZ2 . TRP A 270 ? 0.41276 0.47453 0.42711 0.05122  0.01065  -0.00901 269 TRP A CZ2 
1890 C CZ3 . TRP A 270 ? 0.48387 0.50827 0.46726 0.05075  0.00320  -0.01208 269 TRP A CZ3 
1891 C CH2 . TRP A 270 ? 0.37993 0.42206 0.37428 0.05530  0.00804  -0.01070 269 TRP A CH2 
1892 N N   . CYS A 271 ? 0.33910 0.37200 0.35810 0.01156  0.00003  -0.01373 270 CYS A N   
1893 C CA  . CYS A 271 ? 0.34747 0.37957 0.37220 0.00480  0.00445  -0.01179 270 CYS A CA  
1894 C C   . CYS A 271 ? 0.34021 0.37798 0.37739 -0.00008 0.00251  -0.01458 270 CYS A C   
1895 O O   . CYS A 271 ? 0.34118 0.38179 0.38869 -0.00507 0.00637  -0.01281 270 CYS A O   
1896 C CB  . CYS A 271 ? 0.34577 0.36462 0.35686 0.00277  0.00544  -0.01023 270 CYS A CB  
1897 S SG  . CYS A 271 ? 0.38818 0.39849 0.38678 0.00591  0.00740  -0.00737 270 CYS A SG  
1898 N N   . LEU A 272 ? 0.33173 0.36978 0.36700 0.00161  -0.00382 -0.01908 271 LEU A N   
1899 C CA  . LEU A 272 ? 0.37555 0.41748 0.42120 -0.00249 -0.00763 -0.02353 271 LEU A CA  
1900 C C   . LEU A 272 ? 0.37438 0.43145 0.43717 -0.00243 -0.01133 -0.02632 271 LEU A C   
1901 O O   . LEU A 272 ? 0.34123 0.40196 0.41038 -0.00387 -0.01786 -0.03200 271 LEU A O   
1902 C CB  . LEU A 272 ? 0.38428 0.41759 0.41619 -0.00011 -0.01281 -0.02740 271 LEU A CB  
1903 C CG  . LEU A 272 ? 0.32429 0.34524 0.34164 -0.00069 -0.00879 -0.02414 271 LEU A CG  
1904 C CD1 . LEU A 272 ? 0.34612 0.36040 0.34913 0.00305  -0.01318 -0.02715 271 LEU A CD1 
1905 C CD2 . LEU A 272 ? 0.30656 0.32573 0.33142 -0.00655 -0.00408 -0.02265 271 LEU A CD2 
1906 N N   . ALA A 273 ? 0.36967 0.43666 0.44033 -0.00038 -0.00756 -0.02271 272 ALA A N   
1907 C CA  . ALA A 273 ? 0.38309 0.46784 0.47444 -0.00162 -0.00942 -0.02398 272 ALA A CA  
1908 C C   . ALA A 273 ? 0.39220 0.47968 0.50125 -0.01125 -0.00864 -0.02458 272 ALA A C   
1909 O O   . ALA A 273 ? 0.34689 0.42710 0.45580 -0.01562 -0.00231 -0.02037 272 ALA A O   
1910 C CB  . ALA A 273 ? 0.33992 0.43513 0.43622 0.00265  -0.00326 -0.01861 272 ALA A CB  
1911 N N   . LEU A 274 ? 0.34967 0.44708 0.47406 -0.01444 -0.01560 -0.02999 273 LEU A N   
1912 C CA  . LEU A 274 ? 0.33728 0.43492 0.47923 -0.02438 -0.01613 -0.03138 273 LEU A CA  
1913 C C   . LEU A 274 ? 0.35880 0.46517 0.51824 -0.02959 -0.00677 -0.02318 273 LEU A C   
1914 O O   . LEU A 274 ? 0.38229 0.48009 0.54634 -0.03620 -0.00233 -0.02021 273 LEU A O   
1915 C CB  . LEU A 274 ? 0.40044 0.50858 0.55728 -0.02702 -0.02666 -0.03949 273 LEU A CB  
1916 C CG  . LEU A 274 ? 0.38301 0.48126 0.52434 -0.02323 -0.03684 -0.04864 273 LEU A CG  
1917 C CD1 . LEU A 274 ? 0.44126 0.55335 0.59976 -0.02542 -0.04798 -0.05694 273 LEU A CD1 
1918 C CD2 . LEU A 274 ? 0.39723 0.47599 0.52771 -0.02682 -0.03595 -0.05043 273 LEU A CD2 
1919 N N   . ARG A 275 ? 0.36254 0.48623 0.53143 -0.02581 -0.00330 -0.01900 274 ARG A N   
1920 C CA  . ARG A 275 ? 0.38721 0.51994 0.57138 -0.02975 0.00675  -0.01012 274 ARG A CA  
1921 C C   . ARG A 275 ? 0.35448 0.47782 0.51978 -0.02382 0.01537  -0.00377 274 ARG A C   
1922 O O   . ARG A 275 ? 0.32519 0.44679 0.47382 -0.01480 0.01464  -0.00469 274 ARG A O   
1923 C CB  . ARG A 275 ? 0.37707 0.53496 0.58160 -0.02810 0.00788  -0.00760 274 ARG A CB  
1924 C CG  . ARG A 275 ? 0.46652 0.63732 0.69433 -0.03512 -0.00112 -0.01376 274 ARG A CG  
1925 N N   . PRO A 276 ? 0.33984 0.45664 0.50729 -0.02840 0.02306  0.00252  275 PRO A N   
1926 C CA  . PRO A 276 ? 0.36992 0.47728 0.51832 -0.02261 0.02988  0.00749  275 PRO A CA  
1927 C C   . PRO A 276 ? 0.35624 0.47478 0.49964 -0.01338 0.03447  0.01126  275 PRO A C   
1928 O O   . PRO A 276 ? 0.38434 0.49354 0.50716 -0.00641 0.03481  0.01068  275 PRO A O   
1929 C CB  . PRO A 276 ? 0.39480 0.49795 0.55179 -0.02905 0.03746  0.01448  275 PRO A CB  
1930 C CG  . PRO A 276 ? 0.47273 0.57351 0.64628 -0.03884 0.03216  0.01048  275 PRO A CG  
1931 C CD  . PRO A 276 ? 0.35993 0.47515 0.54583 -0.03902 0.02470  0.00464  275 PRO A CD  
1932 N N   A SER A 277 ? 0.34782 0.48632 0.50995 -0.01304 0.03793  0.01502  276 SER A N   
1933 N N   B SER A 277 ? 0.34732 0.48581 0.50927 -0.01294 0.03805  0.01511  276 SER A N   
1934 C CA  A SER A 277 ? 0.33273 0.48307 0.48989 -0.00261 0.04258  0.01836  276 SER A CA  
1935 C CA  B SER A 277 ? 0.33259 0.48222 0.48864 -0.00233 0.04266  0.01837  276 SER A CA  
1936 C C   A SER A 277 ? 0.36657 0.51369 0.50836 0.00614  0.03506  0.01138  276 SER A C   
1937 C C   B SER A 277 ? 0.36646 0.51386 0.50840 0.00623  0.03504  0.01136  276 SER A C   
1938 O O   A SER A 277 ? 0.36297 0.51181 0.49243 0.01635  0.03778  0.01263  276 SER A O   
1939 O O   B SER A 277 ? 0.36164 0.51210 0.49248 0.01651  0.03774  0.01265  276 SER A O   
1940 C CB  A SER A 277 ? 0.35604 0.53136 0.53900 -0.00409 0.04787  0.02403  276 SER A CB  
1941 C CB  B SER A 277 ? 0.35561 0.52999 0.53641 -0.00326 0.04874  0.02461  276 SER A CB  
1942 O OG  A SER A 277 ? 0.31221 0.49820 0.51282 -0.00906 0.03981  0.01848  276 SER A OG  
1943 O OG  B SER A 277 ? 0.38077 0.55676 0.57279 -0.00968 0.05775  0.03330  276 SER A OG  
1944 N N   . ASP A 278 ? 0.32810 0.46948 0.46906 0.00314  0.02563  0.00411  277 ASP A N   
1945 C CA  . ASP A 278 ? 0.33401 0.47129 0.46012 0.01160  0.01859  -0.00159 277 ASP A CA  
1946 C C   . ASP A 278 ? 0.37233 0.48667 0.47264 0.01422  0.01665  -0.00371 277 ASP A C   
1947 O O   . ASP A 278 ? 0.37580 0.48349 0.46174 0.02122  0.01160  -0.00729 277 ASP A O   
1948 C CB  . ASP A 278 ? 0.28692 0.42999 0.42289 0.00869  0.00909  -0.00812 277 ASP A CB  
1949 C CG  . ASP A 278 ? 0.43647 0.60548 0.59898 0.00746  0.00900  -0.00713 277 ASP A CG  
1950 O OD1 . ASP A 278 ? 0.37351 0.55735 0.54242 0.01321  0.01554  -0.00193 277 ASP A OD1 
1951 O OD2 . ASP A 278 ? 0.39598 0.57124 0.57321 0.00096  0.00203  -0.01183 277 ASP A OD2 
1952 N N   . ARG A 279 ? 0.30164 0.40396 0.39651 0.00864  0.02046  -0.00122 278 ARG A N   
1953 C CA  . ARG A 279 ? 0.33719 0.42034 0.41074 0.00989  0.01905  -0.00256 278 ARG A CA  
1954 C C   . ARG A 279 ? 0.39800 0.47767 0.45817 0.01753  0.02310  0.00006  278 ARG A C   
1955 O O   . ARG A 279 ? 0.36953 0.46041 0.43634 0.02083  0.02917  0.00424  278 ARG A O   
1956 C CB  . ARG A 279 ? 0.29163 0.36572 0.36598 0.00182  0.02121  -0.00114 278 ARG A CB  
1957 C CG  . ARG A 279 ? 0.40777 0.48053 0.49038 -0.00459 0.01566  -0.00554 278 ARG A CG  
1958 C CD  . ARG A 279 ? 0.34947 0.41395 0.43476 -0.01175 0.01810  -0.00423 278 ARG A CD  
1959 N NE  . ARG A 279 ? 0.32681 0.39422 0.42601 -0.01766 0.01347  -0.00829 278 ARG A NE  
1960 C CZ  . ARG A 279 ? 0.35435 0.41980 0.46523 -0.02457 0.01579  -0.00678 278 ARG A CZ  
1961 N NH1 . ARG A 279 ? 0.29408 0.35418 0.40293 -0.02591 0.02303  -0.00079 278 ARG A NH1 
1962 N NH2 . ARG A 279 ? 0.31849 0.38695 0.44333 -0.02997 0.01028  -0.01152 278 ARG A NH2 
1963 N N   . PRO A 280 ? 0.37070 0.43484 0.41197 0.02053  0.01975  -0.00231 279 PRO A N   
1964 C CA  . PRO A 280 ? 0.33507 0.39325 0.36257 0.02735  0.02203  -0.00125 279 PRO A CA  
1965 C C   . PRO A 280 ? 0.35420 0.41092 0.38108 0.02422  0.02767  0.00260  279 PRO A C   
1966 O O   . PRO A 280 ? 0.35226 0.40637 0.38419 0.01664  0.02864  0.00388  279 PRO A O   
1967 C CB  . PRO A 280 ? 0.35255 0.39286 0.36279 0.02832  0.01605  -0.00475 279 PRO A CB  
1968 C CG  . PRO A 280 ? 0.37430 0.41033 0.38818 0.01985  0.01377  -0.00546 279 PRO A CG  
1969 C CD  . PRO A 280 ? 0.34616 0.39692 0.37797 0.01718  0.01403  -0.00566 279 PRO A CD  
1970 N N   . THR A 281 ? 0.34063 0.39882 0.36001 0.03136  0.03115  0.00419  280 THR A N   
1971 C CA  . THR A 281 ? 0.37181 0.42512 0.38413 0.03070  0.03461  0.00669  280 THR A CA  
1972 C C   . THR A 281 ? 0.41701 0.45309 0.41434 0.02853  0.02895  0.00295  280 THR A C   
1973 O O   . THR A 281 ? 0.40701 0.43398 0.39768 0.02880  0.02326  -0.00082 280 THR A O   
1974 C CB  . THR A 281 ? 0.40657 0.46643 0.41286 0.04060  0.03918  0.00867  280 THR A CB  
1975 O OG1 . THR A 281 ? 0.40477 0.45604 0.39647 0.04862  0.03408  0.00351  280 THR A OG1 
1976 C CG2 . THR A 281 ? 0.38522 0.46492 0.40806 0.04302  0.04601  0.01375  280 THR A CG2 
1977 N N   . PHE A 282 ? 0.37295 0.40509 0.36520 0.02662  0.03065  0.00456  281 PHE A N   
1978 C CA  . PHE A 282 ? 0.40807 0.42631 0.38823 0.02419  0.02529  0.00132  281 PHE A CA  
1979 C C   . PHE A 282 ? 0.45415 0.46328 0.42057 0.03113  0.02066  -0.00305 281 PHE A C   
1980 O O   . PHE A 282 ? 0.39369 0.38995 0.35261 0.02854  0.01494  -0.00616 281 PHE A O   
1981 C CB  . PHE A 282 ? 0.38981 0.40827 0.36788 0.02216  0.02756  0.00363  281 PHE A CB  
1982 C CG  . PHE A 282 ? 0.37354 0.39452 0.36152 0.01458  0.02991  0.00664  281 PHE A CG  
1983 C CD1 . PHE A 282 ? 0.45331 0.48356 0.45364 0.01333  0.03554  0.01080  281 PHE A CD1 
1984 C CD2 . PHE A 282 ? 0.45110 0.46498 0.43650 0.00880  0.02654  0.00540  281 PHE A CD2 
1985 C CE1 . PHE A 282 ? 0.51423 0.54421 0.52251 0.00702  0.03711  0.01280  281 PHE A CE1 
1986 C CE2 . PHE A 282 ? 0.50037 0.51618 0.49350 0.00343  0.02874  0.00769  281 PHE A CE2 
1987 C CZ  . PHE A 282 ? 0.48427 0.50689 0.48803 0.00281  0.03365  0.01090  281 PHE A CZ  
1988 N N   . GLU A 283 ? 0.41071 0.42575 0.37331 0.04038  0.02331  -0.00306 282 GLU A N   
1989 C CA  . GLU A 283 ? 0.41591 0.42110 0.36432 0.04867  0.01868  -0.00801 282 GLU A CA  
1990 C C   . GLU A 283 ? 0.45353 0.45293 0.40200 0.04921  0.01469  -0.01024 282 GLU A C   
1991 O O   . GLU A 283 ? 0.42962 0.41267 0.36653 0.04999  0.00850  -0.01419 282 GLU A O   
1992 C CB  . GLU A 283 ? 0.40178 0.41714 0.34653 0.06028  0.02340  -0.00715 282 GLU A CB  
1993 C CG  . GLU A 283 ? 0.42475 0.43047 0.35481 0.07102  0.01887  -0.01276 282 GLU A CG  
1994 C CD  . GLU A 283 ? 0.56938 0.58543 0.49327 0.08413  0.02390  -0.01211 282 GLU A CD  
1995 O OE1 . GLU A 283 ? 0.59395 0.62813 0.52926 0.08473  0.03223  -0.00570 282 GLU A OE1 
1996 O OE2 . GLU A 283 ? 0.59224 0.59767 0.49951 0.09408  0.01966  -0.01780 282 GLU A OE2 
1997 N N   . GLU A 284 ? 0.38055 0.39281 0.34231 0.04856  0.01778  -0.00762 283 GLU A N   
1998 C CA  . GLU A 284 ? 0.40055 0.40931 0.36232 0.05028  0.01370  -0.00964 283 GLU A CA  
1999 C C   . GLU A 284 ? 0.40622 0.40193 0.36525 0.04170  0.00903  -0.01036 283 GLU A C   
2000 O O   . GLU A 284 ? 0.40495 0.38871 0.35534 0.04405  0.00418  -0.01247 283 GLU A O   
2001 C CB  . GLU A 284 ? 0.41732 0.44532 0.39577 0.05114  0.01729  -0.00715 283 GLU A CB  
2002 C CG  . GLU A 284 ? 0.45077 0.49347 0.43224 0.06154  0.02220  -0.00577 283 GLU A CG  
2003 C CD  . GLU A 284 ? 0.46836 0.53268 0.47044 0.06031  0.02596  -0.00256 283 GLU A CD  
2004 O OE1 . GLU A 284 ? 0.40455 0.47577 0.42049 0.05081  0.02862  0.00048  283 GLU A OE1 
2005 O OE2 . GLU A 284 ? 0.53064 0.60478 0.53549 0.06884  0.02576  -0.00334 283 GLU A OE2 
2006 N N   . ILE A 285 ? 0.37625 0.37400 0.34196 0.03252  0.01086  -0.00807 284 ILE A N   
2007 C CA  . ILE A 285 ? 0.38066 0.36720 0.34284 0.02529  0.00734  -0.00813 284 ILE A CA  
2008 C C   . ILE A 285 ? 0.40493 0.37421 0.35317 0.02548  0.00303  -0.01007 284 ILE A C   
2009 O O   . ILE A 285 ? 0.40568 0.36256 0.34690 0.02477  -0.00089 -0.01056 284 ILE A O   
2010 C CB  . ILE A 285 ? 0.39308 0.38519 0.36379 0.01694  0.01044  -0.00553 284 ILE A CB  
2011 C CG1 . ILE A 285 ? 0.36784 0.37391 0.35278 0.01564  0.01362  -0.00417 284 ILE A CG1 
2012 C CG2 . ILE A 285 ? 0.39081 0.37245 0.35673 0.01054  0.00760  -0.00505 284 ILE A CG2 
2013 C CD1 . ILE A 285 ? 0.41497 0.42502 0.40774 0.00872  0.01693  -0.00181 284 ILE A CD1 
2014 N N   . GLN A 286 ? 0.37160 0.33942 0.31564 0.02636  0.00343  -0.01111 285 GLN A N   
2015 C CA  . GLN A 286 ? 0.39816 0.34965 0.33101 0.02465  -0.00172 -0.01365 285 GLN A CA  
2016 C C   . GLN A 286 ? 0.46789 0.40618 0.38864 0.03291  -0.00611 -0.01746 285 GLN A C   
2017 O O   . GLN A 286 ? 0.48207 0.40284 0.39405 0.03031  -0.01136 -0.01929 285 GLN A O   
2018 C CB  . GLN A 286 ? 0.39536 0.35019 0.32720 0.02361  -0.00114 -0.01450 285 GLN A CB  
2019 C CG  . GLN A 286 ? 0.38955 0.35226 0.33089 0.01470  0.00163  -0.01086 285 GLN A CG  
2020 C CD  . GLN A 286 ? 0.43043 0.39528 0.36968 0.01372  0.00082  -0.01181 285 GLN A CD  
2021 O OE1 . GLN A 286 ? 0.42645 0.39827 0.36349 0.02032  0.00317  -0.01233 285 GLN A OE1 
2022 N NE2 . GLN A 286 ? 0.43414 0.39412 0.37419 0.00589  -0.00247 -0.01170 285 GLN A NE2 
2023 N N   . ASN A 287 ? 0.39573 0.34176 0.31638 0.04276  -0.00409 -0.01839 286 ASN A N   
2024 C CA  . ASN A 287 ? 0.45872 0.39234 0.36767 0.05208  -0.00813 -0.02181 286 ASN A CA  
2025 C C   . ASN A 287 ? 0.49752 0.42758 0.40750 0.05238  -0.00966 -0.02006 286 ASN A C   
2026 O O   . ASN A 287 ? 0.47607 0.39567 0.37626 0.06098  -0.01294 -0.02230 286 ASN A O   
2027 C CB  . ASN A 287 ? 0.49004 0.43489 0.39732 0.06463  -0.00511 -0.02362 286 ASN A CB  
2028 C CG  . ASN A 287 ? 0.53051 0.47313 0.42950 0.06845  -0.00534 -0.02669 286 ASN A CG  
2029 O OD1 . ASN A 287 ? 0.54441 0.47083 0.43445 0.06442  -0.01073 -0.02993 286 ASN A OD1 
2030 N ND2 . ASN A 287 ? 0.50118 0.46084 0.40340 0.07634  0.00045  -0.02549 286 ASN A ND2 
2031 N N   . HIS A 288 ? 0.45903 0.39725 0.37932 0.04451  -0.00762 -0.01639 287 HIS A N   
2032 C CA  . HIS A 288 ? 0.47017 0.40639 0.39028 0.04600  -0.00942 -0.01497 287 HIS A CA  
2033 C C   . HIS A 288 ? 0.44401 0.35640 0.35051 0.04501  -0.01424 -0.01465 287 HIS A C   
2034 O O   . HIS A 288 ? 0.47362 0.37419 0.37639 0.03766  -0.01559 -0.01420 287 HIS A O   
2035 C CB  . HIS A 288 ? 0.43361 0.38209 0.36571 0.03798  -0.00680 -0.01196 287 HIS A CB  
2036 C CG  . HIS A 288 ? 0.43846 0.39014 0.37172 0.04116  -0.00871 -0.01133 287 HIS A CG  
2037 N ND1 . HIS A 288 ? 0.43352 0.37059 0.35684 0.04058  -0.01184 -0.00952 287 HIS A ND1 
2038 C CD2 . HIS A 288 ? 0.41255 0.38095 0.35589 0.04511  -0.00824 -0.01219 287 HIS A CD2 
2039 C CE1 . HIS A 288 ? 0.44894 0.39331 0.37429 0.04523  -0.01350 -0.00964 287 HIS A CE1 
2040 N NE2 . HIS A 288 ? 0.41786 0.38165 0.35611 0.04764  -0.01188 -0.01175 287 HIS A NE2 
2041 N N   . PRO A 289 ? 0.48024 0.38525 0.37961 0.05235  -0.01699 -0.01451 288 PRO A N   
2042 C CA  . PRO A 289 ? 0.52794 0.40801 0.41383 0.05151  -0.02109 -0.01300 288 PRO A CA  
2043 C C   . PRO A 289 ? 0.50289 0.37749 0.39091 0.03940  -0.02009 -0.00810 288 PRO A C   
2044 O O   . PRO A 289 ? 0.50959 0.36506 0.39044 0.03415  -0.02236 -0.00657 288 PRO A O   
2045 C CB  . PRO A 289 ? 0.52913 0.40759 0.40912 0.06231  -0.02317 -0.01259 288 PRO A CB  
2046 C CG  . PRO A 289 ? 0.62883 0.52740 0.51628 0.07147  -0.02147 -0.01616 288 PRO A CG  
2047 C CD  . PRO A 289 ? 0.53351 0.45149 0.43588 0.06328  -0.01682 -0.01600 288 PRO A CD  
2048 N N   . TRP A 290 ? 0.48448 0.37561 0.38271 0.03472  -0.01672 -0.00568 289 TRP A N   
2049 C CA  . TRP A 290 ? 0.47793 0.36567 0.37753 0.02481  -0.01501 -0.00079 289 TRP A CA  
2050 C C   . TRP A 290 ? 0.47553 0.36113 0.37927 0.01529  -0.01406 -0.00063 289 TRP A C   
2051 O O   . TRP A 290 ? 0.49509 0.37345 0.39836 0.00714  -0.01338 0.00375  289 TRP A O   
2052 C CB  . TRP A 290 ? 0.45014 0.35598 0.35875 0.02320  -0.01206 0.00043  289 TRP A CB  
2053 C CG  . TRP A 290 ? 0.45677 0.35904 0.36440 0.01535  -0.00988 0.00576  289 TRP A CG  
2054 C CD1 . TRP A 290 ? 0.44926 0.33919 0.34712 0.01593  -0.01038 0.01077  289 TRP A CD1 
2055 C CD2 . TRP A 290 ? 0.43273 0.34408 0.34889 0.00670  -0.00630 0.00732  289 TRP A CD2 
2056 N NE1 . TRP A 290 ? 0.45673 0.34894 0.35707 0.00806  -0.00679 0.01564  289 TRP A NE1 
2057 C CE2 . TRP A 290 ? 0.41814 0.32356 0.32978 0.00250  -0.00449 0.01327  289 TRP A CE2 
2058 C CE3 . TRP A 290 ? 0.42916 0.35324 0.35584 0.00293  -0.00409 0.00482  289 TRP A CE3 
2059 C CZ2 . TRP A 290 ? 0.47045 0.38374 0.38837 -0.00493 -0.00060 0.01630  289 TRP A CZ2 
2060 C CZ3 . TRP A 290 ? 0.45829 0.38854 0.39058 -0.00437 -0.00080 0.00759  289 TRP A CZ3 
2061 C CH2 . TRP A 290 ? 0.43624 0.36178 0.36446 -0.00808 0.00090  0.01306  289 TRP A CH2 
2062 N N   . MET A 291 ? 0.43077 0.32405 0.33892 0.01653  -0.01384 -0.00491 290 MET A N   
2063 C CA  . MET A 291 ? 0.46279 0.35779 0.37568 0.00856  -0.01332 -0.00529 290 MET A CA  
2064 C C   . MET A 291 ? 0.51745 0.39394 0.42210 0.00713  -0.01835 -0.00784 290 MET A C   
2065 O O   . MET A 291 ? 0.51601 0.39381 0.42450 0.00060  -0.01926 -0.00884 290 MET A O   
2066 C CB  . MET A 291 ? 0.44169 0.35452 0.36268 0.01098  -0.01036 -0.00804 290 MET A CB  
2067 C CG  . MET A 291 ? 0.48468 0.41497 0.41625 0.00962  -0.00577 -0.00575 290 MET A CG  
2068 S SD  . MET A 291 ? 0.52117 0.46248 0.46249 0.00074  -0.00214 -0.00363 290 MET A SD  
2069 C CE  . MET A 291 ? 0.42916 0.35906 0.36716 -0.00769 -0.00362 0.00030  290 MET A CE  
2070 N N   . GLN A 292 ? 0.51980 0.37876 0.41319 0.01333  -0.02223 -0.00936 291 GLN A N   
2071 C CA  . GLN A 292 ? 0.60913 0.44861 0.49395 0.01288  -0.02804 -0.01338 291 GLN A CA  
2072 C C   . GLN A 292 ? 0.63797 0.46326 0.52401 0.00065  -0.03009 -0.00913 291 GLN A C   
2073 O O   . GLN A 292 ? 0.54310 0.36976 0.43267 -0.00476 -0.02672 -0.00219 291 GLN A O   
2074 C CB  . GLN A 292 ? 0.58437 0.40845 0.45584 0.02496  -0.03160 -0.01681 291 GLN A CB  
2075 C CG  . GLN A 292 ? 0.60919 0.44956 0.48090 0.03731  -0.02938 -0.02107 291 GLN A CG  
2076 C CD  . GLN A 292 ? 0.73899 0.59657 0.61826 0.03552  -0.02704 -0.02382 291 GLN A CD  
2077 O OE1 . GLN A 292 ? 0.66494 0.51429 0.53894 0.03502  -0.03091 -0.02843 291 GLN A OE1 
2078 N NE2 . GLN A 292 ? 0.54442 0.42514 0.43562 0.03481  -0.02108 -0.02103 291 GLN A NE2 
2079 N N   . ASP A 293 ? 0.57540 0.38833 0.45911 -0.00373 -0.03568 -0.01340 292 ASP A N   
2080 C CA  . ASP A 293 ? 0.65245 0.45029 0.53870 -0.01612 -0.03879 -0.00995 292 ASP A CA  
2081 C C   . ASP A 293 ? 0.61651 0.43234 0.51743 -0.02755 -0.03379 -0.00355 292 ASP A C   
2082 O O   . ASP A 293 ? 0.56819 0.37864 0.47278 -0.03588 -0.03174 0.00394  292 ASP A O   
2083 C CB  . ASP A 293 ? 0.69486 0.46967 0.57178 -0.01510 -0.03987 -0.00520 292 ASP A CB  
2084 C CG  . ASP A 293 ? 0.83514 0.58767 0.69677 -0.00453 -0.04618 -0.01200 292 ASP A CG  
2085 O OD1 . ASP A 293 ? 0.92280 0.66888 0.78137 -0.00375 -0.05211 -0.02007 292 ASP A OD1 
2086 O OD2 . ASP A 293 ? 0.91077 0.65277 0.76263 0.00415  -0.04545 -0.00968 292 ASP A OD2 
2087 N N   . VAL A 294 ? 0.48796 0.32530 0.39688 -0.02724 -0.03141 -0.00602 293 VAL A N   
2088 C CA  . VAL A 294 ? 0.50586 0.36127 0.42793 -0.03604 -0.02658 -0.00057 293 VAL A CA  
2089 C C   . VAL A 294 ? 0.53362 0.38308 0.46303 -0.04867 -0.03039 0.00113  293 VAL A C   
2090 O O   . VAL A 294 ? 0.54204 0.37849 0.46835 -0.05063 -0.03792 -0.00476 293 VAL A O   
2091 C CB  . VAL A 294 ? 0.49539 0.37243 0.42302 -0.03174 -0.02375 -0.00389 293 VAL A CB  
2092 C CG1 . VAL A 294 ? 0.51249 0.38769 0.43826 -0.03087 -0.02983 -0.01126 293 VAL A CG1 
2093 C CG2 . VAL A 294 ? 0.47584 0.37155 0.41551 -0.03822 -0.01797 0.00181  293 VAL A CG2 
2094 N N   . LEU A 295 ? 0.47511 0.33477 0.41474 -0.05718 -0.02540 0.00904  294 LEU A N   
2095 C CA  . LEU A 295 ? 0.49111 0.35200 0.44212 -0.06996 -0.02794 0.01154  294 LEU A CA  
2096 C C   . LEU A 295 ? 0.49388 0.37253 0.45317 -0.07102 -0.03035 0.00609  294 LEU A C   
2097 O O   . LEU A 295 ? 0.49442 0.38905 0.45373 -0.06380 -0.02652 0.00434  294 LEU A O   
2098 C CB  . LEU A 295 ? 0.48323 0.35379 0.44320 -0.07727 -0.02051 0.02244  294 LEU A CB  
2099 C CG  . LEU A 295 ? 0.52680 0.38127 0.47988 -0.07803 -0.01728 0.03045  294 LEU A CG  
2100 C CD1 . LEU A 295 ? 0.58609 0.45635 0.54835 -0.08364 -0.00879 0.04101  294 LEU A CD1 
2101 C CD2 . LEU A 295 ? 0.54761 0.37718 0.49891 -0.08561 -0.02387 0.03058  294 LEU A CD2 
2102 N N   . LEU A 296 ? 0.50445 0.38011 0.47126 -0.08034 -0.03694 0.00376  295 LEU A N   
2103 C CA  . LEU A 296 ? 0.56356 0.45824 0.53999 -0.08254 -0.03942 -0.00004 295 LEU A CA  
2104 C C   . LEU A 296 ? 0.52595 0.44330 0.51695 -0.08849 -0.03195 0.00841  295 LEU A C   
2105 O O   . LEU A 296 ? 0.46636 0.38248 0.46146 -0.09386 -0.02645 0.01710  295 LEU A O   
2106 C CB  . LEU A 296 ? 0.55529 0.43984 0.53570 -0.09075 -0.05029 -0.00608 295 LEU A CB  
2107 C CG  . LEU A 296 ? 0.61133 0.46955 0.57704 -0.08611 -0.05932 -0.01505 295 LEU A CG  
2108 C CD1 . LEU A 296 ? 0.61262 0.46332 0.58522 -0.09619 -0.07082 -0.02124 295 LEU A CD1 
2109 C CD2 . LEU A 296 ? 0.59384 0.45455 0.54543 -0.07063 -0.05940 -0.02257 295 LEU A CD2 
2110 N N   . PRO A 297 ? 0.50840 0.44675 0.50636 -0.08650 -0.03128 0.00638  296 PRO A N   
2111 C CA  . PRO A 297 ? 0.46075 0.42093 0.47134 -0.09011 -0.02379 0.01414  296 PRO A CA  
2112 C C   . PRO A 297 ? 0.52184 0.48503 0.54678 -0.10356 -0.02396 0.02096  296 PRO A C   
2113 O O   . PRO A 297 ? 0.49142 0.46253 0.52146 -0.10600 -0.01576 0.03006  296 PRO A O   
2114 C CB  . PRO A 297 ? 0.46659 0.44519 0.48104 -0.08535 -0.02548 0.00940  296 PRO A CB  
2115 C CG  . PRO A 297 ? 0.53513 0.50264 0.53482 -0.07499 -0.02904 0.00137  296 PRO A CG  
2116 C CD  . PRO A 297 ? 0.53527 0.47872 0.52761 -0.07833 -0.03582 -0.00223 296 PRO A CD  
2117 N N   . GLN A 298 ? 0.50566 0.46261 0.53735 -0.11237 -0.03319 0.01687  297 GLN A N   
2118 C CA  . GLN A 298 ? 0.54194 0.50268 0.59027 -0.12683 -0.03343 0.02400  297 GLN A CA  
2119 C C   . GLN A 298 ? 0.51677 0.45831 0.56043 -0.13106 -0.02889 0.03207  297 GLN A C   
2120 O O   . GLN A 298 ? 0.54867 0.49899 0.60351 -0.13880 -0.02213 0.04280  297 GLN A O   
2121 C CB  . GLN A 298 ? 0.55492 0.51119 0.61173 -0.13582 -0.04598 0.01650  297 GLN A CB  
2122 N N   . GLU A 299 ? 0.54921 0.46500 0.57601 -0.12532 -0.03223 0.02758  298 GLU A N   
2123 C CA  . GLU A 299 ? 0.56618 0.46303 0.58572 -0.12675 -0.02761 0.03546  298 GLU A CA  
2124 C C   . GLU A 299 ? 0.52560 0.43625 0.54233 -0.12022 -0.01563 0.04413  298 GLU A C   
2125 O O   . GLU A 299 ? 0.55749 0.46675 0.57726 -0.12522 -0.00901 0.05498  298 GLU A O   
2126 C CB  . GLU A 299 ? 0.58243 0.45163 0.58275 -0.11837 -0.03323 0.02812  298 GLU A CB  
2127 C CG  . GLU A 299 ? 0.61889 0.46663 0.61766 -0.12385 -0.04554 0.01954  298 GLU A CG  
2128 C CD  . GLU A 299 ? 0.66267 0.48723 0.64042 -0.11143 -0.05036 0.01093  298 GLU A CD  
2129 O OE1 . GLU A 299 ? 0.57048 0.40059 0.53754 -0.09881 -0.04483 0.01043  298 GLU A OE1 
2130 O OE2 . GLU A 299 ? 0.70577 0.50683 0.67806 -0.11404 -0.05990 0.00443  298 GLU A OE2 
2131 N N   . THR A 300 ? 0.46983 0.39329 0.48030 -0.10880 -0.01288 0.03947  299 THR A N   
2132 C CA  . THR A 300 ? 0.48468 0.42088 0.49185 -0.10180 -0.00300 0.04553  299 THR A CA  
2133 C C   . THR A 300 ? 0.50888 0.46591 0.53098 -0.10892 0.00381  0.05487  299 THR A C   
2134 O O   . THR A 300 ? 0.50452 0.46401 0.52430 -0.10785 0.01184  0.06382  299 THR A O   
2135 C CB  . THR A 300 ? 0.52212 0.46880 0.52345 -0.09044 -0.00260 0.03808  299 THR A CB  
2136 O OG1 . THR A 300 ? 0.49889 0.42849 0.48762 -0.08369 -0.00829 0.03012  299 THR A OG1 
2137 C CG2 . THR A 300 ? 0.50445 0.46111 0.50124 -0.08289 0.00598  0.04251  299 THR A CG2 
2138 N N   . ALA A 301 ? 0.54349 0.51680 0.58061 -0.11533 0.00068  0.05299  300 ALA A N   
2139 C CA  . ALA A 301 ? 0.55202 0.54833 0.60509 -0.12148 0.00718  0.06181  300 ALA A CA  
2140 C C   . ALA A 301 ? 0.55468 0.54361 0.61541 -0.13311 0.01000  0.07246  300 ALA A C   
2141 O O   . ALA A 301 ? 0.51902 0.51887 0.58284 -0.13336 0.01972  0.08312  300 ALA A O   
2142 C CB  . ALA A 301 ? 0.46364 0.47913 0.53181 -0.12565 0.00182  0.05691  300 ALA A CB  
2143 N N   . GLU A 302 ? 0.49318 0.46248 0.55619 -0.14237 0.00169  0.06990  301 GLU A N   
2144 C CA  . GLU A 302 ? 0.56990 0.53040 0.64231 -0.15531 0.00377  0.08050  301 GLU A CA  
2145 C C   . GLU A 302 ? 0.63392 0.57796 0.69082 -0.14996 0.01151  0.08907  301 GLU A C   
2146 O O   . GLU A 302 ? 0.60204 0.54978 0.66555 -0.15627 0.01956  0.10223  301 GLU A O   
2147 C CB  . GLU A 302 ? 0.64857 0.58848 0.72569 -0.16591 -0.00844 0.07400  301 GLU A CB  
2148 C CG  . GLU A 302 ? 0.69279 0.64989 0.78606 -0.17193 -0.01703 0.06585  301 GLU A CG  
2149 C CD  . GLU A 302 ? 0.89838 0.83282 0.99238 -0.17988 -0.03095 0.05641  301 GLU A CD  
2150 O OE1 . GLU A 302 ? 0.91541 0.81915 0.99460 -0.17836 -0.03393 0.05485  301 GLU A OE1 
2151 O OE2 . GLU A 302 ? 0.82769 0.77492 0.93637 -0.18682 -0.03938 0.05008  301 GLU A OE2 
2152 N N   . ILE A 303 ? 0.53708 0.46430 0.57346 -0.13782 0.00948  0.08233  302 ILE A N   
2153 C CA  . ILE A 303 ? 0.54162 0.45314 0.56234 -0.13167 0.01556  0.08971  302 ILE A CA  
2154 C C   . ILE A 303 ? 0.61099 0.54250 0.62722 -0.12225 0.02621  0.09562  302 ILE A C   
2155 O O   . ILE A 303 ? 0.53782 0.46848 0.55053 -0.12219 0.03446  0.10731  302 ILE A O   
2156 C CB  . ILE A 303 ? 0.54296 0.42978 0.54450 -0.12209 0.00878  0.08033  302 ILE A CB  
2157 C CG1 . ILE A 303 ? 0.63963 0.50244 0.64282 -0.13059 -0.00147 0.07533  302 ILE A CG1 
2158 C CG2 . ILE A 303 ? 0.57192 0.44626 0.55653 -0.11331 0.01484  0.08727  302 ILE A CG2 
2159 C CD1 . ILE A 303 ? 0.62387 0.46517 0.60877 -0.11974 -0.00861 0.06466  302 ILE A CD1 
2160 N N   . HIS A 304 ? 0.49924 0.44822 0.51480 -0.11377 0.02626  0.08789  303 HIS A N   
2161 C CA  . HIS A 304 ? 0.57449 0.53604 0.58091 -0.10221 0.03412  0.09014  303 HIS A CA  
2162 C C   . HIS A 304 ? 0.58743 0.57773 0.60586 -0.10196 0.04035  0.09318  303 HIS A C   
2163 O O   . HIS A 304 ? 0.58517 0.58516 0.59630 -0.09340 0.04789  0.09719  303 HIS A O   
2164 C CB  . HIS A 304 ? 0.52756 0.48300 0.52017 -0.09002 0.02979  0.07877  303 HIS A CB  
2165 C CG  . HIS A 304 ? 0.52489 0.45491 0.50307 -0.08625 0.02506  0.07599  303 HIS A CG  
2166 N ND1 . HIS A 304 ? 0.57168 0.49115 0.53639 -0.08035 0.02915  0.08214  303 HIS A ND1 
2167 C CD2 . HIS A 304 ? 0.51815 0.43187 0.49224 -0.08603 0.01658  0.06754  303 HIS A CD2 
2168 C CE1 . HIS A 304 ? 0.52825 0.42618 0.48209 -0.07691 0.02328  0.07778  303 HIS A CE1 
2169 N NE2 . HIS A 304 ? 0.56941 0.46339 0.52865 -0.08019 0.01582  0.06888  303 HIS A NE2 
2170 N N   . LEU A 305 ? 0.52711 0.53135 0.56258 -0.10978 0.03699  0.09079  304 LEU A N   
2171 C CA  . LEU A 305 ? 0.54293 0.57463 0.58833 -0.10680 0.04173  0.09149  304 LEU A CA  
2172 C C   . LEU A 305 ? 0.65476 0.70586 0.72017 -0.11750 0.04656  0.10179  304 LEU A C   
2173 O O   . LEU A 305 ? 0.65278 0.72609 0.72288 -0.11293 0.05455  0.10700  304 LEU A O   
2174 C CB  . LEU A 305 ? 0.51329 0.55073 0.56179 -0.10382 0.03434  0.07971  304 LEU A CB  
2175 C CG  . LEU A 305 ? 0.48910 0.51091 0.52124 -0.09392 0.02959  0.06944  304 LEU A CG  
2176 C CD1 . LEU A 305 ? 0.49011 0.52081 0.52641 -0.09087 0.02423  0.06024  304 LEU A CD1 
2177 C CD2 . LEU A 305 ? 0.53017 0.55158 0.54847 -0.08255 0.03600  0.07065  304 LEU A CD2 
2178 N N   . HIS A 306 ? 0.57819 0.62187 0.65603 -0.13141 0.04183  0.10470  305 HIS A N   
2179 C CA  . HIS A 306 ? 0.75807 0.82091 0.85784 -0.14338 0.04640  0.11546  305 HIS A CA  
2180 C C   . HIS A 306 ? 0.67648 0.73767 0.77262 -0.14422 0.05770  0.13034  305 HIS A C   
2181 O O   . HIS A 306 ? 0.86757 0.95287 0.97295 -0.14353 0.06755  0.14009  305 HIS A O   
2182 C CB  . HIS A 306 ? 0.69358 0.74777 0.80910 -0.15916 0.03629  0.11287  305 HIS A CB  
2183 C CG  . HIS A 306 ? 0.66436 0.72220 0.78358 -0.15816 0.02508  0.09888  305 HIS A CG  
2184 N ND1 . HIS A 306 ? 0.63633 0.68326 0.76491 -0.16937 0.01339  0.09254  305 HIS A ND1 
2185 C CD2 . HIS A 306 ? 0.69475 0.76508 0.80855 -0.14673 0.02373  0.09022  305 HIS A CD2 
2186 C CE1 . HIS A 306 ? 0.63642 0.69014 0.76417 -0.16403 0.00550  0.08060  305 HIS A CE1 
2187 N NE2 . HIS A 306 ? 0.62689 0.69473 0.74613 -0.15057 0.01197  0.07962  305 HIS A NE2 
2188 N N   . ARG B 2   ? 0.84557 0.79695 0.69566 0.07808  -0.02554 0.00639  2   ARG B N   
2189 C CA  . ARG B 2   ? 0.81700 0.75926 0.66585 0.07545  -0.02136 -0.00116 2   ARG B CA  
2190 C C   . ARG B 2   ? 0.87660 0.80701 0.72304 0.08297  -0.01080 -0.00374 2   ARG B C   
2191 O O   . ARG B 2   ? 0.85829 0.79234 0.71785 0.09061  -0.00993 0.00066  2   ARG B O   
2192 C CB  . ARG B 2   ? 0.73350 0.68547 0.60207 0.07294  -0.02901 -0.00061 2   ARG B CB  
2193 C CG  . ARG B 2   ? 0.74806 0.69137 0.61611 0.06961  -0.02539 -0.00840 2   ARG B CG  
2194 C CD  . ARG B 2   ? 0.66576 0.61943 0.55320 0.06658  -0.03361 -0.00769 2   ARG B CD  
2195 N NE  . ARG B 2   ? 0.65311 0.61858 0.54294 0.05986  -0.04380 -0.00478 2   ARG B NE  
2196 C CZ  . ARG B 2   ? 0.69555 0.67520 0.59988 0.06146  -0.05205 0.00252  2   ARG B CZ  
2197 N NH1 . ARG B 2   ? 0.57311 0.55755 0.49211 0.06938  -0.05176 0.00770  2   ARG B NH1 
2198 N NH2 . ARG B 2   ? 0.59393 0.58315 0.49800 0.05501  -0.06080 0.00468  2   ARG B NH2 
2199 N N   . LYS B 3   ? 0.81062 0.72691 0.64048 0.08073  -0.00291 -0.01096 3   LYS B N   
2200 C CA  . LYS B 3   ? 0.73176 0.63559 0.55737 0.08738  0.00758  -0.01414 3   LYS B CA  
2201 C C   . LYS B 3   ? 0.73845 0.64381 0.58240 0.09138  0.00771  -0.01456 3   LYS B C   
2202 O O   . LYS B 3   ? 0.76799 0.67781 0.62159 0.08662  0.00255  -0.01662 3   LYS B O   
2203 C CB  . LYS B 3   ? 0.69762 0.58649 0.50296 0.08314  0.01518  -0.02235 3   LYS B CB  
2204 N N   . ARG B 4   ? 0.69219 0.59372 0.54076 0.10021  0.01372  -0.01262 4   ARG B N   
2205 C CA  . ARG B 4   ? 0.61745 0.51817 0.48146 0.10527  0.01573  -0.01332 4   ARG B CA  
2206 C C   . ARG B 4   ? 0.67123 0.55644 0.52402 0.11048  0.02743  -0.01801 4   ARG B C   
2207 O O   . ARG B 4   ? 0.67576 0.55567 0.51686 0.11440  0.03279  -0.01670 4   ARG B O   
2208 C CB  . ARG B 4   ? 0.64263 0.55575 0.52588 0.11172  0.01066  -0.00529 4   ARG B CB  
2209 C CG  . ARG B 4   ? 0.55951 0.46959 0.45529 0.12013  0.01555  -0.00487 4   ARG B CG  
2210 C CD  . ARG B 4   ? 0.54120 0.46505 0.45592 0.12564  0.00933  0.00352  4   ARG B CD  
2211 N NE  . ARG B 4   ? 0.52754 0.44871 0.45365 0.13446  0.01420  0.00457  4   ARG B NE  
2212 C CZ  . ARG B 4   ? 0.51553 0.43832 0.45661 0.13562  0.01297  0.00319  4   ARG B CZ  
2213 N NH1 . ARG B 4   ? 0.51640 0.44257 0.46248 0.12855  0.00763  0.00021  4   ARG B NH1 
2214 N NH2 . ARG B 4   ? 0.50264 0.42359 0.45395 0.14411  0.01723  0.00481  4   ARG B NH2 
2215 N N   . ARG B 5   ? 0.59737 0.47497 0.45296 0.11036  0.03152  -0.02363 5   ARG B N   
2216 C CA  . ARG B 5   ? 0.69081 0.55292 0.53438 0.11464  0.04274  -0.02870 5   ARG B CA  
2217 C C   . ARG B 5   ? 0.60513 0.46394 0.46199 0.11952  0.04603  -0.03067 5   ARG B C   
2218 O O   . ARG B 5   ? 0.58082 0.44748 0.45374 0.11764  0.03997  -0.02994 5   ARG B O   
2219 C CB  . ARG B 5   ? 0.69375 0.54440 0.51699 0.10754  0.04710  -0.03620 5   ARG B CB  
2220 C CG  . ARG B 5   ? 0.75330 0.60378 0.58022 0.10012  0.04377  -0.04149 5   ARG B CG  
2221 C CD  . ARG B 5   ? 0.89356 0.73233 0.69924 0.09352  0.04857  -0.04871 5   ARG B CD  
2222 N NE  . ARG B 5   ? 0.96923 0.80446 0.77663 0.08744  0.04790  -0.05500 5   ARG B NE  
2223 C CZ  . ARG B 5   ? 1.00663 0.83098 0.81328 0.08947  0.05502  -0.06056 5   ARG B CZ  
2224 N NH1 . ARG B 5   ? 0.83436 0.65052 0.63967 0.09770  0.06322  -0.06059 5   ARG B NH1 
2225 N NH2 . ARG B 5   ? 0.99953 0.82116 0.80689 0.08312  0.05388  -0.06626 5   ARG B NH2 
2226 N N   . ARG B 6   ? 0.59317 0.44023 0.44312 0.12603  0.05578  -0.03307 6   ARG B N   
2227 C CA  . ARG B 6   ? 0.60541 0.44612 0.46391 0.13037  0.06068  -0.03635 6   ARG B CA  
2228 C C   . ARG B 6   ? 0.64247 0.47360 0.49216 0.12362  0.06356  -0.04462 6   ARG B C   
2229 O O   . ARG B 6   ? 0.62092 0.44770 0.45489 0.11681  0.06392  -0.04824 6   ARG B O   
2230 C CB  . ARG B 6   ? 0.60238 0.43330 0.45531 0.13949  0.07031  -0.03633 6   ARG B CB  
2231 C CG  . ARG B 6   ? 0.59409 0.43375 0.45557 0.14675  0.06821  -0.02832 6   ARG B CG  
2232 C CD  . ARG B 6   ? 0.62560 0.45440 0.47813 0.15498  0.07824  -0.02894 6   ARG B CD  
2233 N NE  . ARG B 6   ? 0.66087 0.49778 0.52489 0.16291  0.07665  -0.02160 6   ARG B NE  
2234 C CZ  . ARG B 6   ? 0.65111 0.49142 0.53210 0.16973  0.07669  -0.01904 6   ARG B CZ  
2235 N NH1 . ARG B 6   ? 0.61310 0.44962 0.50204 0.16978  0.07816  -0.02303 6   ARG B NH1 
2236 N NH2 . ARG B 6   ? 0.57738 0.42530 0.46781 0.17657  0.07506  -0.01227 6   ARG B NH2 
2237 N N   . HIS B 7   ? 0.61298 0.44086 0.47309 0.12556  0.06560  -0.04761 7   HIS B N   
2238 C CA  . HIS B 7   ? 0.67705 0.49571 0.53061 0.11980  0.06864  -0.05549 7   HIS B CA  
2239 C C   . HIS B 7   ? 0.66209 0.46833 0.51514 0.12617  0.07818  -0.05956 7   HIS B C   
2240 O O   . HIS B 7   ? 0.64782 0.45773 0.51638 0.13292  0.07809  -0.05639 7   HIS B O   
2241 C CB  . HIS B 7   ? 0.61093 0.43962 0.47941 0.11384  0.05981  -0.05549 7   HIS B CB  
2242 C CG  . HIS B 7   ? 0.59175 0.43316 0.46202 0.10763  0.04999  -0.05143 7   HIS B CG  
2243 N ND1 . HIS B 7   ? 0.57896 0.43417 0.46247 0.11074  0.04288  -0.04344 7   HIS B ND1 
2244 C CD2 . HIS B 7   ? 0.64061 0.48294 0.50089 0.09856  0.04615  -0.05426 7   HIS B CD2 
2245 C CE1 . HIS B 7   ? 0.60924 0.47330 0.49079 0.10386  0.03507  -0.04149 7   HIS B CE1 
2246 N NE2 . HIS B 7   ? 0.61552 0.47204 0.48302 0.09641  0.03685  -0.04797 7   HIS B NE2 
2247 N N   . PRO B 8   ? 0.78450 0.57613 0.62041 0.12427  0.08640  -0.06654 8   PRO B N   
2248 C CA  . PRO B 8   ? 0.77740 0.55668 0.61194 0.13061  0.09584  -0.07041 8   PRO B CA  
2249 C C   . PRO B 8   ? 0.77969 0.55928 0.62824 0.12973  0.09453  -0.07332 8   PRO B C   
2250 O O   . PRO B 8   ? 0.83767 0.62326 0.69200 0.12254  0.08803  -0.07473 8   PRO B O   
2251 C CB  . PRO B 8   ? 0.89753 0.66183 0.70863 0.12741  0.10406  -0.07715 8   PRO B CB  
2252 C CG  . PRO B 8   ? 0.99961 0.76820 0.80386 0.11715  0.09792  -0.07899 8   PRO B CG  
2253 C CD  . PRO B 8   ? 0.83711 0.62267 0.65387 0.11623  0.08749  -0.07129 8   PRO B CD  
2254 N N   . SER B 9   ? 0.86789 0.64098 0.72212 0.13738  0.10081  -0.07414 9   SER B N   
2255 C CA  . SER B 9   ? 0.88357 0.65407 0.74901 0.13753  0.10164  -0.07769 9   SER B CA  
2256 C C   . SER B 9   ? 1.01435 0.76902 0.86428 0.13408  0.10978  -0.08648 9   SER B C   
2257 O O   . SER B 9   ? 1.00274 0.75621 0.85599 0.12847  0.10809  -0.09090 9   SER B O   
2258 C CB  . SER B 9   ? 0.81871 0.58988 0.69802 0.14759  0.10443  -0.07428 9   SER B CB  
2259 O OG  . SER B 9   ? 0.82684 0.61323 0.72215 0.15045  0.09639  -0.06628 9   SER B OG  
# 
