data_8QY7
# 
_entry.id   8QY7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8QY7         pdb_00008qy7 10.2210/pdb8qy7/pdb 
WWPDB D_1292134300 ?            ?                   
EMDB  EMD-18747    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.pdbx_database_id_DOI'    
7  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  2 'Structure model' '_citation.title'                   
9  2 'Structure model' '_citation.year'                    
10 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8QY7 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Zorya anti-bacteriophage defense system ZorD apo form' 
_pdbx_database_related.db_id          EMD-18747 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nicholas.taylor@cpr.ku.dk 
_pdbx_contact_author.name_first         Nicholas 
_pdbx_contact_author.name_last          Taylor 
_pdbx_contact_author.name_mi            'M. I.' 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0761-4921 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hu, H.'         1 ? 
'Taylor, N.M.I.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure and mechanism of the Zorya anti-phage defense system.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-024-08493-8 
_citation.pdbx_database_id_PubMed   39662505 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hu, H.'          1  0000-0001-7774-9157 
primary 'Popp, P.F.'      2  0000-0002-7825-1550 
primary 'Hughes, T.C.D.'  3  0009-0005-6057-4852 
primary 'Roa-Eguiara, A.' 4  0000-0003-3962-7583 
primary 'Rutbeek, N.R.'   5  0000-0002-6851-8223 
primary 'Martin, F.J.O.'  6  0000-0001-6456-2860 
primary 'Hendriks, I.A.'  7  0000-0002-1439-3701 
primary 'Payne, L.J.'     8  0000-0003-2305-6827 
primary 'Yan, Y.'         9  ?                   
primary 'Humolli, D.'     10 0009-0002-1819-6155 
primary 'Klein-Sousa, V.' 11 0000-0002-0430-4330 
primary 'Songailiene, I.' 12 ?                   
primary 'Wang, Y.'        13 0000-0001-9156-0377 
primary 'Nielsen, M.L.'   14 0000-0002-0067-9039 
primary 'Berry, R.M.'     15 0000-0002-0331-473X 
primary 'Harms, A.'       16 0000-0003-2106-1286 
primary 'Erhardt, M.'     17 0000-0001-6292-619X 
primary 'Jackson, S.A.'   18 0000-0002-4512-3093 
primary 'Taylor, N.M.I.'  19 0000-0003-0761-4921 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'DEAD/DEAH box helicase' 
_entity.formula_weight             122880.039 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MLKRLLSKLTGNRQQIEHHLKNQYQVEENGLSFPLSLVDDSQLWALASWLEQLAEEDYLISLTDRWLLSWEALYRLLEDE
EHASSLPLIGVPDILPLRASLSSRGALSDSDFRVWIAEWATFPARKPIRFSRTGAILTHDNQQYLLSRENWALLQATEQL
SAQQIQTPGETTNQLGWAAIRKCAKLAAAKFDDYLEKTHVIKPTSLSLRLRKATVADTAVIEIEPHFEDQPANWLGSFDK
NLQVHDSYRIPGENGELSHVIIPPEVKEVLNSIHSIPGRRVAGSEALSFVRNPYTFLGEDAASVIAPEEHEQALFDARIF
FHHFRLIPQLNTENKITEVTLILEPVSPVPQPEITFVFSAPWELDKFIQQLGISVAAQMPAGSWQGYELELSQFTEQQWH
DCQALLTRWQQEIEGKEFSDVLDIAKYGDRVIGIGEFEKISSPWLTKAQSENWLPDGIDFSAFSIETLSGWQPENPLHFD
ELQEIITQAEAAGETYITTPWNDSQLPLDAAKTFSKNWEKQQITANEYQGNVADKTARAVLKIEQNIEETAYIKQRRNSL
LNARHAEPEIPLSLKEHIRLKDHQREGVAWLQQLFLRSPEETAGCLLADDMGLGKTLQILSFLVWFIEKFPQEPPNLIVA
PVSLLDNWERELNNFFYTAGIPVLKLYGETIKAVKYPKQAIPAHLQSKGIKNLLKPGWQGEAKIILTTYETLRDQEFSLA
RQPWSIMVCDEAQKIKNPAALITHAANAVQARFKVACTGTPVENTLVDLWSLFDFAQPGLLGALNEFGKQYVRPIENEDG
RDTERLESLRALIEPQTLRRTKEEVARDLPQKIEVESCKQLTLSGVQKQLYLSSVANWQQQQALREGMQQAGTGMLGLLH
RLKLICAHPAIVNPEPRFRDNSPKLNWLLKILAEIKHTSKDKVIIFTELRDLQRELQHAIHQNFGFRPVIINGDSSTKSQ
SQNSRQRLIDDFQAQPGFGVIILSTVAVGFGVNVQKANHVIHFTRCWNPAKEDQATDRAYRIGQTKNVYVYYPTVRDTEI
TTFEETLDDLLQRRRALARDMLCATPDLNCADFETILKGA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MLKRLLSKLTGNRQQIEHHLKNQYQVEENGLSFPLSLVDDSQLWALASWLEQLAEEDYLISLTDRWLLSWEALYRLLEDE
EHASSLPLIGVPDILPLRASLSSRGALSDSDFRVWIAEWATFPARKPIRFSRTGAILTHDNQQYLLSRENWALLQATEQL
SAQQIQTPGETTNQLGWAAIRKCAKLAAAKFDDYLEKTHVIKPTSLSLRLRKATVADTAVIEIEPHFEDQPANWLGSFDK
NLQVHDSYRIPGENGELSHVIIPPEVKEVLNSIHSIPGRRVAGSEALSFVRNPYTFLGEDAASVIAPEEHEQALFDARIF
FHHFRLIPQLNTENKITEVTLILEPVSPVPQPEITFVFSAPWELDKFIQQLGISVAAQMPAGSWQGYELELSQFTEQQWH
DCQALLTRWQQEIEGKEFSDVLDIAKYGDRVIGIGEFEKISSPWLTKAQSENWLPDGIDFSAFSIETLSGWQPENPLHFD
ELQEIITQAEAAGETYITTPWNDSQLPLDAAKTFSKNWEKQQITANEYQGNVADKTARAVLKIEQNIEETAYIKQRRNSL
LNARHAEPEIPLSLKEHIRLKDHQREGVAWLQQLFLRSPEETAGCLLADDMGLGKTLQILSFLVWFIEKFPQEPPNLIVA
PVSLLDNWERELNNFFYTAGIPVLKLYGETIKAVKYPKQAIPAHLQSKGIKNLLKPGWQGEAKIILTTYETLRDQEFSLA
RQPWSIMVCDEAQKIKNPAALITHAANAVQARFKVACTGTPVENTLVDLWSLFDFAQPGLLGALNEFGKQYVRPIENEDG
RDTERLESLRALIEPQTLRRTKEEVARDLPQKIEVESCKQLTLSGVQKQLYLSSVANWQQQQALREGMQQAGTGMLGLLH
RLKLICAHPAIVNPEPRFRDNSPKLNWLLKILAEIKHTSKDKVIIFTELRDLQRELQHAIHQNFGFRPVIINGDSSTKSQ
SQNSRQRLIDDFQAQPGFGVIILSTVAVGFGVNVQKANHVIHFTRCWNPAKEDQATDRAYRIGQTKNVYVYYPTVRDTEI
TTFEETLDDLLQRRRALARDMLCATPDLNCADFETILKGA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    LEU n 
1 3    LYS n 
1 4    ARG n 
1 5    LEU n 
1 6    LEU n 
1 7    SER n 
1 8    LYS n 
1 9    LEU n 
1 10   THR n 
1 11   GLY n 
1 12   ASN n 
1 13   ARG n 
1 14   GLN n 
1 15   GLN n 
1 16   ILE n 
1 17   GLU n 
1 18   HIS n 
1 19   HIS n 
1 20   LEU n 
1 21   LYS n 
1 22   ASN n 
1 23   GLN n 
1 24   TYR n 
1 25   GLN n 
1 26   VAL n 
1 27   GLU n 
1 28   GLU n 
1 29   ASN n 
1 30   GLY n 
1 31   LEU n 
1 32   SER n 
1 33   PHE n 
1 34   PRO n 
1 35   LEU n 
1 36   SER n 
1 37   LEU n 
1 38   VAL n 
1 39   ASP n 
1 40   ASP n 
1 41   SER n 
1 42   GLN n 
1 43   LEU n 
1 44   TRP n 
1 45   ALA n 
1 46   LEU n 
1 47   ALA n 
1 48   SER n 
1 49   TRP n 
1 50   LEU n 
1 51   GLU n 
1 52   GLN n 
1 53   LEU n 
1 54   ALA n 
1 55   GLU n 
1 56   GLU n 
1 57   ASP n 
1 58   TYR n 
1 59   LEU n 
1 60   ILE n 
1 61   SER n 
1 62   LEU n 
1 63   THR n 
1 64   ASP n 
1 65   ARG n 
1 66   TRP n 
1 67   LEU n 
1 68   LEU n 
1 69   SER n 
1 70   TRP n 
1 71   GLU n 
1 72   ALA n 
1 73   LEU n 
1 74   TYR n 
1 75   ARG n 
1 76   LEU n 
1 77   LEU n 
1 78   GLU n 
1 79   ASP n 
1 80   GLU n 
1 81   GLU n 
1 82   HIS n 
1 83   ALA n 
1 84   SER n 
1 85   SER n 
1 86   LEU n 
1 87   PRO n 
1 88   LEU n 
1 89   ILE n 
1 90   GLY n 
1 91   VAL n 
1 92   PRO n 
1 93   ASP n 
1 94   ILE n 
1 95   LEU n 
1 96   PRO n 
1 97   LEU n 
1 98   ARG n 
1 99   ALA n 
1 100  SER n 
1 101  LEU n 
1 102  SER n 
1 103  SER n 
1 104  ARG n 
1 105  GLY n 
1 106  ALA n 
1 107  LEU n 
1 108  SER n 
1 109  ASP n 
1 110  SER n 
1 111  ASP n 
1 112  PHE n 
1 113  ARG n 
1 114  VAL n 
1 115  TRP n 
1 116  ILE n 
1 117  ALA n 
1 118  GLU n 
1 119  TRP n 
1 120  ALA n 
1 121  THR n 
1 122  PHE n 
1 123  PRO n 
1 124  ALA n 
1 125  ARG n 
1 126  LYS n 
1 127  PRO n 
1 128  ILE n 
1 129  ARG n 
1 130  PHE n 
1 131  SER n 
1 132  ARG n 
1 133  THR n 
1 134  GLY n 
1 135  ALA n 
1 136  ILE n 
1 137  LEU n 
1 138  THR n 
1 139  HIS n 
1 140  ASP n 
1 141  ASN n 
1 142  GLN n 
1 143  GLN n 
1 144  TYR n 
1 145  LEU n 
1 146  LEU n 
1 147  SER n 
1 148  ARG n 
1 149  GLU n 
1 150  ASN n 
1 151  TRP n 
1 152  ALA n 
1 153  LEU n 
1 154  LEU n 
1 155  GLN n 
1 156  ALA n 
1 157  THR n 
1 158  GLU n 
1 159  GLN n 
1 160  LEU n 
1 161  SER n 
1 162  ALA n 
1 163  GLN n 
1 164  GLN n 
1 165  ILE n 
1 166  GLN n 
1 167  THR n 
1 168  PRO n 
1 169  GLY n 
1 170  GLU n 
1 171  THR n 
1 172  THR n 
1 173  ASN n 
1 174  GLN n 
1 175  LEU n 
1 176  GLY n 
1 177  TRP n 
1 178  ALA n 
1 179  ALA n 
1 180  ILE n 
1 181  ARG n 
1 182  LYS n 
1 183  CYS n 
1 184  ALA n 
1 185  LYS n 
1 186  LEU n 
1 187  ALA n 
1 188  ALA n 
1 189  ALA n 
1 190  LYS n 
1 191  PHE n 
1 192  ASP n 
1 193  ASP n 
1 194  TYR n 
1 195  LEU n 
1 196  GLU n 
1 197  LYS n 
1 198  THR n 
1 199  HIS n 
1 200  VAL n 
1 201  ILE n 
1 202  LYS n 
1 203  PRO n 
1 204  THR n 
1 205  SER n 
1 206  LEU n 
1 207  SER n 
1 208  LEU n 
1 209  ARG n 
1 210  LEU n 
1 211  ARG n 
1 212  LYS n 
1 213  ALA n 
1 214  THR n 
1 215  VAL n 
1 216  ALA n 
1 217  ASP n 
1 218  THR n 
1 219  ALA n 
1 220  VAL n 
1 221  ILE n 
1 222  GLU n 
1 223  ILE n 
1 224  GLU n 
1 225  PRO n 
1 226  HIS n 
1 227  PHE n 
1 228  GLU n 
1 229  ASP n 
1 230  GLN n 
1 231  PRO n 
1 232  ALA n 
1 233  ASN n 
1 234  TRP n 
1 235  LEU n 
1 236  GLY n 
1 237  SER n 
1 238  PHE n 
1 239  ASP n 
1 240  LYS n 
1 241  ASN n 
1 242  LEU n 
1 243  GLN n 
1 244  VAL n 
1 245  HIS n 
1 246  ASP n 
1 247  SER n 
1 248  TYR n 
1 249  ARG n 
1 250  ILE n 
1 251  PRO n 
1 252  GLY n 
1 253  GLU n 
1 254  ASN n 
1 255  GLY n 
1 256  GLU n 
1 257  LEU n 
1 258  SER n 
1 259  HIS n 
1 260  VAL n 
1 261  ILE n 
1 262  ILE n 
1 263  PRO n 
1 264  PRO n 
1 265  GLU n 
1 266  VAL n 
1 267  LYS n 
1 268  GLU n 
1 269  VAL n 
1 270  LEU n 
1 271  ASN n 
1 272  SER n 
1 273  ILE n 
1 274  HIS n 
1 275  SER n 
1 276  ILE n 
1 277  PRO n 
1 278  GLY n 
1 279  ARG n 
1 280  ARG n 
1 281  VAL n 
1 282  ALA n 
1 283  GLY n 
1 284  SER n 
1 285  GLU n 
1 286  ALA n 
1 287  LEU n 
1 288  SER n 
1 289  PHE n 
1 290  VAL n 
1 291  ARG n 
1 292  ASN n 
1 293  PRO n 
1 294  TYR n 
1 295  THR n 
1 296  PHE n 
1 297  LEU n 
1 298  GLY n 
1 299  GLU n 
1 300  ASP n 
1 301  ALA n 
1 302  ALA n 
1 303  SER n 
1 304  VAL n 
1 305  ILE n 
1 306  ALA n 
1 307  PRO n 
1 308  GLU n 
1 309  GLU n 
1 310  HIS n 
1 311  GLU n 
1 312  GLN n 
1 313  ALA n 
1 314  LEU n 
1 315  PHE n 
1 316  ASP n 
1 317  ALA n 
1 318  ARG n 
1 319  ILE n 
1 320  PHE n 
1 321  PHE n 
1 322  HIS n 
1 323  HIS n 
1 324  PHE n 
1 325  ARG n 
1 326  LEU n 
1 327  ILE n 
1 328  PRO n 
1 329  GLN n 
1 330  LEU n 
1 331  ASN n 
1 332  THR n 
1 333  GLU n 
1 334  ASN n 
1 335  LYS n 
1 336  ILE n 
1 337  THR n 
1 338  GLU n 
1 339  VAL n 
1 340  THR n 
1 341  LEU n 
1 342  ILE n 
1 343  LEU n 
1 344  GLU n 
1 345  PRO n 
1 346  VAL n 
1 347  SER n 
1 348  PRO n 
1 349  VAL n 
1 350  PRO n 
1 351  GLN n 
1 352  PRO n 
1 353  GLU n 
1 354  ILE n 
1 355  THR n 
1 356  PHE n 
1 357  VAL n 
1 358  PHE n 
1 359  SER n 
1 360  ALA n 
1 361  PRO n 
1 362  TRP n 
1 363  GLU n 
1 364  LEU n 
1 365  ASP n 
1 366  LYS n 
1 367  PHE n 
1 368  ILE n 
1 369  GLN n 
1 370  GLN n 
1 371  LEU n 
1 372  GLY n 
1 373  ILE n 
1 374  SER n 
1 375  VAL n 
1 376  ALA n 
1 377  ALA n 
1 378  GLN n 
1 379  MET n 
1 380  PRO n 
1 381  ALA n 
1 382  GLY n 
1 383  SER n 
1 384  TRP n 
1 385  GLN n 
1 386  GLY n 
1 387  TYR n 
1 388  GLU n 
1 389  LEU n 
1 390  GLU n 
1 391  LEU n 
1 392  SER n 
1 393  GLN n 
1 394  PHE n 
1 395  THR n 
1 396  GLU n 
1 397  GLN n 
1 398  GLN n 
1 399  TRP n 
1 400  HIS n 
1 401  ASP n 
1 402  CYS n 
1 403  GLN n 
1 404  ALA n 
1 405  LEU n 
1 406  LEU n 
1 407  THR n 
1 408  ARG n 
1 409  TRP n 
1 410  GLN n 
1 411  GLN n 
1 412  GLU n 
1 413  ILE n 
1 414  GLU n 
1 415  GLY n 
1 416  LYS n 
1 417  GLU n 
1 418  PHE n 
1 419  SER n 
1 420  ASP n 
1 421  VAL n 
1 422  LEU n 
1 423  ASP n 
1 424  ILE n 
1 425  ALA n 
1 426  LYS n 
1 427  TYR n 
1 428  GLY n 
1 429  ASP n 
1 430  ARG n 
1 431  VAL n 
1 432  ILE n 
1 433  GLY n 
1 434  ILE n 
1 435  GLY n 
1 436  GLU n 
1 437  PHE n 
1 438  GLU n 
1 439  LYS n 
1 440  ILE n 
1 441  SER n 
1 442  SER n 
1 443  PRO n 
1 444  TRP n 
1 445  LEU n 
1 446  THR n 
1 447  LYS n 
1 448  ALA n 
1 449  GLN n 
1 450  SER n 
1 451  GLU n 
1 452  ASN n 
1 453  TRP n 
1 454  LEU n 
1 455  PRO n 
1 456  ASP n 
1 457  GLY n 
1 458  ILE n 
1 459  ASP n 
1 460  PHE n 
1 461  SER n 
1 462  ALA n 
1 463  PHE n 
1 464  SER n 
1 465  ILE n 
1 466  GLU n 
1 467  THR n 
1 468  LEU n 
1 469  SER n 
1 470  GLY n 
1 471  TRP n 
1 472  GLN n 
1 473  PRO n 
1 474  GLU n 
1 475  ASN n 
1 476  PRO n 
1 477  LEU n 
1 478  HIS n 
1 479  PHE n 
1 480  ASP n 
1 481  GLU n 
1 482  LEU n 
1 483  GLN n 
1 484  GLU n 
1 485  ILE n 
1 486  ILE n 
1 487  THR n 
1 488  GLN n 
1 489  ALA n 
1 490  GLU n 
1 491  ALA n 
1 492  ALA n 
1 493  GLY n 
1 494  GLU n 
1 495  THR n 
1 496  TYR n 
1 497  ILE n 
1 498  THR n 
1 499  THR n 
1 500  PRO n 
1 501  TRP n 
1 502  ASN n 
1 503  ASP n 
1 504  SER n 
1 505  GLN n 
1 506  LEU n 
1 507  PRO n 
1 508  LEU n 
1 509  ASP n 
1 510  ALA n 
1 511  ALA n 
1 512  LYS n 
1 513  THR n 
1 514  PHE n 
1 515  SER n 
1 516  LYS n 
1 517  ASN n 
1 518  TRP n 
1 519  GLU n 
1 520  LYS n 
1 521  GLN n 
1 522  GLN n 
1 523  ILE n 
1 524  THR n 
1 525  ALA n 
1 526  ASN n 
1 527  GLU n 
1 528  TYR n 
1 529  GLN n 
1 530  GLY n 
1 531  ASN n 
1 532  VAL n 
1 533  ALA n 
1 534  ASP n 
1 535  LYS n 
1 536  THR n 
1 537  ALA n 
1 538  ARG n 
1 539  ALA n 
1 540  VAL n 
1 541  LEU n 
1 542  LYS n 
1 543  ILE n 
1 544  GLU n 
1 545  GLN n 
1 546  ASN n 
1 547  ILE n 
1 548  GLU n 
1 549  GLU n 
1 550  THR n 
1 551  ALA n 
1 552  TYR n 
1 553  ILE n 
1 554  LYS n 
1 555  GLN n 
1 556  ARG n 
1 557  ARG n 
1 558  ASN n 
1 559  SER n 
1 560  LEU n 
1 561  LEU n 
1 562  ASN n 
1 563  ALA n 
1 564  ARG n 
1 565  HIS n 
1 566  ALA n 
1 567  GLU n 
1 568  PRO n 
1 569  GLU n 
1 570  ILE n 
1 571  PRO n 
1 572  LEU n 
1 573  SER n 
1 574  LEU n 
1 575  LYS n 
1 576  GLU n 
1 577  HIS n 
1 578  ILE n 
1 579  ARG n 
1 580  LEU n 
1 581  LYS n 
1 582  ASP n 
1 583  HIS n 
1 584  GLN n 
1 585  ARG n 
1 586  GLU n 
1 587  GLY n 
1 588  VAL n 
1 589  ALA n 
1 590  TRP n 
1 591  LEU n 
1 592  GLN n 
1 593  GLN n 
1 594  LEU n 
1 595  PHE n 
1 596  LEU n 
1 597  ARG n 
1 598  SER n 
1 599  PRO n 
1 600  GLU n 
1 601  GLU n 
1 602  THR n 
1 603  ALA n 
1 604  GLY n 
1 605  CYS n 
1 606  LEU n 
1 607  LEU n 
1 608  ALA n 
1 609  ASP n 
1 610  ASP n 
1 611  MET n 
1 612  GLY n 
1 613  LEU n 
1 614  GLY n 
1 615  LYS n 
1 616  THR n 
1 617  LEU n 
1 618  GLN n 
1 619  ILE n 
1 620  LEU n 
1 621  SER n 
1 622  PHE n 
1 623  LEU n 
1 624  VAL n 
1 625  TRP n 
1 626  PHE n 
1 627  ILE n 
1 628  GLU n 
1 629  LYS n 
1 630  PHE n 
1 631  PRO n 
1 632  GLN n 
1 633  GLU n 
1 634  PRO n 
1 635  PRO n 
1 636  ASN n 
1 637  LEU n 
1 638  ILE n 
1 639  VAL n 
1 640  ALA n 
1 641  PRO n 
1 642  VAL n 
1 643  SER n 
1 644  LEU n 
1 645  LEU n 
1 646  ASP n 
1 647  ASN n 
1 648  TRP n 
1 649  GLU n 
1 650  ARG n 
1 651  GLU n 
1 652  LEU n 
1 653  ASN n 
1 654  ASN n 
1 655  PHE n 
1 656  PHE n 
1 657  TYR n 
1 658  THR n 
1 659  ALA n 
1 660  GLY n 
1 661  ILE n 
1 662  PRO n 
1 663  VAL n 
1 664  LEU n 
1 665  LYS n 
1 666  LEU n 
1 667  TYR n 
1 668  GLY n 
1 669  GLU n 
1 670  THR n 
1 671  ILE n 
1 672  LYS n 
1 673  ALA n 
1 674  VAL n 
1 675  LYS n 
1 676  TYR n 
1 677  PRO n 
1 678  LYS n 
1 679  GLN n 
1 680  ALA n 
1 681  ILE n 
1 682  PRO n 
1 683  ALA n 
1 684  HIS n 
1 685  LEU n 
1 686  GLN n 
1 687  SER n 
1 688  LYS n 
1 689  GLY n 
1 690  ILE n 
1 691  LYS n 
1 692  ASN n 
1 693  LEU n 
1 694  LEU n 
1 695  LYS n 
1 696  PRO n 
1 697  GLY n 
1 698  TRP n 
1 699  GLN n 
1 700  GLY n 
1 701  GLU n 
1 702  ALA n 
1 703  LYS n 
1 704  ILE n 
1 705  ILE n 
1 706  LEU n 
1 707  THR n 
1 708  THR n 
1 709  TYR n 
1 710  GLU n 
1 711  THR n 
1 712  LEU n 
1 713  ARG n 
1 714  ASP n 
1 715  GLN n 
1 716  GLU n 
1 717  PHE n 
1 718  SER n 
1 719  LEU n 
1 720  ALA n 
1 721  ARG n 
1 722  GLN n 
1 723  PRO n 
1 724  TRP n 
1 725  SER n 
1 726  ILE n 
1 727  MET n 
1 728  VAL n 
1 729  CYS n 
1 730  ASP n 
1 731  GLU n 
1 732  ALA n 
1 733  GLN n 
1 734  LYS n 
1 735  ILE n 
1 736  LYS n 
1 737  ASN n 
1 738  PRO n 
1 739  ALA n 
1 740  ALA n 
1 741  LEU n 
1 742  ILE n 
1 743  THR n 
1 744  HIS n 
1 745  ALA n 
1 746  ALA n 
1 747  ASN n 
1 748  ALA n 
1 749  VAL n 
1 750  GLN n 
1 751  ALA n 
1 752  ARG n 
1 753  PHE n 
1 754  LYS n 
1 755  VAL n 
1 756  ALA n 
1 757  CYS n 
1 758  THR n 
1 759  GLY n 
1 760  THR n 
1 761  PRO n 
1 762  VAL n 
1 763  GLU n 
1 764  ASN n 
1 765  THR n 
1 766  LEU n 
1 767  VAL n 
1 768  ASP n 
1 769  LEU n 
1 770  TRP n 
1 771  SER n 
1 772  LEU n 
1 773  PHE n 
1 774  ASP n 
1 775  PHE n 
1 776  ALA n 
1 777  GLN n 
1 778  PRO n 
1 779  GLY n 
1 780  LEU n 
1 781  LEU n 
1 782  GLY n 
1 783  ALA n 
1 784  LEU n 
1 785  ASN n 
1 786  GLU n 
1 787  PHE n 
1 788  GLY n 
1 789  LYS n 
1 790  GLN n 
1 791  TYR n 
1 792  VAL n 
1 793  ARG n 
1 794  PRO n 
1 795  ILE n 
1 796  GLU n 
1 797  ASN n 
1 798  GLU n 
1 799  ASP n 
1 800  GLY n 
1 801  ARG n 
1 802  ASP n 
1 803  THR n 
1 804  GLU n 
1 805  ARG n 
1 806  LEU n 
1 807  GLU n 
1 808  SER n 
1 809  LEU n 
1 810  ARG n 
1 811  ALA n 
1 812  LEU n 
1 813  ILE n 
1 814  GLU n 
1 815  PRO n 
1 816  GLN n 
1 817  THR n 
1 818  LEU n 
1 819  ARG n 
1 820  ARG n 
1 821  THR n 
1 822  LYS n 
1 823  GLU n 
1 824  GLU n 
1 825  VAL n 
1 826  ALA n 
1 827  ARG n 
1 828  ASP n 
1 829  LEU n 
1 830  PRO n 
1 831  GLN n 
1 832  LYS n 
1 833  ILE n 
1 834  GLU n 
1 835  VAL n 
1 836  GLU n 
1 837  SER n 
1 838  CYS n 
1 839  LYS n 
1 840  GLN n 
1 841  LEU n 
1 842  THR n 
1 843  LEU n 
1 844  SER n 
1 845  GLY n 
1 846  VAL n 
1 847  GLN n 
1 848  LYS n 
1 849  GLN n 
1 850  LEU n 
1 851  TYR n 
1 852  LEU n 
1 853  SER n 
1 854  SER n 
1 855  VAL n 
1 856  ALA n 
1 857  ASN n 
1 858  TRP n 
1 859  GLN n 
1 860  GLN n 
1 861  GLN n 
1 862  GLN n 
1 863  ALA n 
1 864  LEU n 
1 865  ARG n 
1 866  GLU n 
1 867  GLY n 
1 868  MET n 
1 869  GLN n 
1 870  GLN n 
1 871  ALA n 
1 872  GLY n 
1 873  THR n 
1 874  GLY n 
1 875  MET n 
1 876  LEU n 
1 877  GLY n 
1 878  LEU n 
1 879  LEU n 
1 880  HIS n 
1 881  ARG n 
1 882  LEU n 
1 883  LYS n 
1 884  LEU n 
1 885  ILE n 
1 886  CYS n 
1 887  ALA n 
1 888  HIS n 
1 889  PRO n 
1 890  ALA n 
1 891  ILE n 
1 892  VAL n 
1 893  ASN n 
1 894  PRO n 
1 895  GLU n 
1 896  PRO n 
1 897  ARG n 
1 898  PHE n 
1 899  ARG n 
1 900  ASP n 
1 901  ASN n 
1 902  SER n 
1 903  PRO n 
1 904  LYS n 
1 905  LEU n 
1 906  ASN n 
1 907  TRP n 
1 908  LEU n 
1 909  LEU n 
1 910  LYS n 
1 911  ILE n 
1 912  LEU n 
1 913  ALA n 
1 914  GLU n 
1 915  ILE n 
1 916  LYS n 
1 917  HIS n 
1 918  THR n 
1 919  SER n 
1 920  LYS n 
1 921  ASP n 
1 922  LYS n 
1 923  VAL n 
1 924  ILE n 
1 925  ILE n 
1 926  PHE n 
1 927  THR n 
1 928  GLU n 
1 929  LEU n 
1 930  ARG n 
1 931  ASP n 
1 932  LEU n 
1 933  GLN n 
1 934  ARG n 
1 935  GLU n 
1 936  LEU n 
1 937  GLN n 
1 938  HIS n 
1 939  ALA n 
1 940  ILE n 
1 941  HIS n 
1 942  GLN n 
1 943  ASN n 
1 944  PHE n 
1 945  GLY n 
1 946  PHE n 
1 947  ARG n 
1 948  PRO n 
1 949  VAL n 
1 950  ILE n 
1 951  ILE n 
1 952  ASN n 
1 953  GLY n 
1 954  ASP n 
1 955  SER n 
1 956  SER n 
1 957  THR n 
1 958  LYS n 
1 959  SER n 
1 960  GLN n 
1 961  SER n 
1 962  GLN n 
1 963  ASN n 
1 964  SER n 
1 965  ARG n 
1 966  GLN n 
1 967  ARG n 
1 968  LEU n 
1 969  ILE n 
1 970  ASP n 
1 971  ASP n 
1 972  PHE n 
1 973  GLN n 
1 974  ALA n 
1 975  GLN n 
1 976  PRO n 
1 977  GLY n 
1 978  PHE n 
1 979  GLY n 
1 980  VAL n 
1 981  ILE n 
1 982  ILE n 
1 983  LEU n 
1 984  SER n 
1 985  THR n 
1 986  VAL n 
1 987  ALA n 
1 988  VAL n 
1 989  GLY n 
1 990  PHE n 
1 991  GLY n 
1 992  VAL n 
1 993  ASN n 
1 994  VAL n 
1 995  GLN n 
1 996  LYS n 
1 997  ALA n 
1 998  ASN n 
1 999  HIS n 
1 1000 VAL n 
1 1001 ILE n 
1 1002 HIS n 
1 1003 PHE n 
1 1004 THR n 
1 1005 ARG n 
1 1006 CYS n 
1 1007 TRP n 
1 1008 ASN n 
1 1009 PRO n 
1 1010 ALA n 
1 1011 LYS n 
1 1012 GLU n 
1 1013 ASP n 
1 1014 GLN n 
1 1015 ALA n 
1 1016 THR n 
1 1017 ASP n 
1 1018 ARG n 
1 1019 ALA n 
1 1020 TYR n 
1 1021 ARG n 
1 1022 ILE n 
1 1023 GLY n 
1 1024 GLN n 
1 1025 THR n 
1 1026 LYS n 
1 1027 ASN n 
1 1028 VAL n 
1 1029 TYR n 
1 1030 VAL n 
1 1031 TYR n 
1 1032 TYR n 
1 1033 PRO n 
1 1034 THR n 
1 1035 VAL n 
1 1036 ARG n 
1 1037 ASP n 
1 1038 THR n 
1 1039 GLU n 
1 1040 ILE n 
1 1041 THR n 
1 1042 THR n 
1 1043 PHE n 
1 1044 GLU n 
1 1045 GLU n 
1 1046 THR n 
1 1047 LEU n 
1 1048 ASP n 
1 1049 ASP n 
1 1050 LEU n 
1 1051 LEU n 
1 1052 GLN n 
1 1053 ARG n 
1 1054 ARG n 
1 1055 ARG n 
1 1056 ALA n 
1 1057 LEU n 
1 1058 ALA n 
1 1059 ARG n 
1 1060 ASP n 
1 1061 MET n 
1 1062 LEU n 
1 1063 CYS n 
1 1064 ALA n 
1 1065 THR n 
1 1066 PRO n 
1 1067 ASP n 
1 1068 LEU n 
1 1069 ASN n 
1 1070 CYS n 
1 1071 ALA n 
1 1072 ASP n 
1 1073 PHE n 
1 1074 GLU n 
1 1075 THR n 
1 1076 ILE n 
1 1077 LEU n 
1 1078 LYS n 
1 1079 GLY n 
1 1080 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1080 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 BF481_003650 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     562 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?    ?   ?   A . n 
A 1 2    LEU 2    2    ?    ?   ?   A . n 
A 1 3    LYS 3    3    ?    ?   ?   A . n 
A 1 4    ARG 4    4    ?    ?   ?   A . n 
A 1 5    LEU 5    5    ?    ?   ?   A . n 
A 1 6    LEU 6    6    ?    ?   ?   A . n 
A 1 7    SER 7    7    ?    ?   ?   A . n 
A 1 8    LYS 8    8    ?    ?   ?   A . n 
A 1 9    LEU 9    9    ?    ?   ?   A . n 
A 1 10   THR 10   10   ?    ?   ?   A . n 
A 1 11   GLY 11   11   ?    ?   ?   A . n 
A 1 12   ASN 12   12   ?    ?   ?   A . n 
A 1 13   ARG 13   13   ?    ?   ?   A . n 
A 1 14   GLN 14   14   ?    ?   ?   A . n 
A 1 15   GLN 15   15   ?    ?   ?   A . n 
A 1 16   ILE 16   16   ?    ?   ?   A . n 
A 1 17   GLU 17   17   ?    ?   ?   A . n 
A 1 18   HIS 18   18   ?    ?   ?   A . n 
A 1 19   HIS 19   19   ?    ?   ?   A . n 
A 1 20   LEU 20   20   ?    ?   ?   A . n 
A 1 21   LYS 21   21   21   LYS LYS A . n 
A 1 22   ASN 22   22   22   ASN ASN A . n 
A 1 23   GLN 23   23   23   GLN GLN A . n 
A 1 24   TYR 24   24   24   TYR TYR A . n 
A 1 25   GLN 25   25   25   GLN GLN A . n 
A 1 26   VAL 26   26   26   VAL VAL A . n 
A 1 27   GLU 27   27   27   GLU GLU A . n 
A 1 28   GLU 28   28   28   GLU GLU A . n 
A 1 29   ASN 29   29   29   ASN ASN A . n 
A 1 30   GLY 30   30   30   GLY GLY A . n 
A 1 31   LEU 31   31   31   LEU LEU A . n 
A 1 32   SER 32   32   32   SER SER A . n 
A 1 33   PHE 33   33   33   PHE PHE A . n 
A 1 34   PRO 34   34   34   PRO PRO A . n 
A 1 35   LEU 35   35   35   LEU LEU A . n 
A 1 36   SER 36   36   36   SER SER A . n 
A 1 37   LEU 37   37   37   LEU LEU A . n 
A 1 38   VAL 38   38   38   VAL VAL A . n 
A 1 39   ASP 39   39   39   ASP ASP A . n 
A 1 40   ASP 40   40   40   ASP ASP A . n 
A 1 41   SER 41   41   41   SER SER A . n 
A 1 42   GLN 42   42   42   GLN GLN A . n 
A 1 43   LEU 43   43   43   LEU LEU A . n 
A 1 44   TRP 44   44   44   TRP TRP A . n 
A 1 45   ALA 45   45   45   ALA ALA A . n 
A 1 46   LEU 46   46   46   LEU LEU A . n 
A 1 47   ALA 47   47   47   ALA ALA A . n 
A 1 48   SER 48   48   48   SER SER A . n 
A 1 49   TRP 49   49   49   TRP TRP A . n 
A 1 50   LEU 50   50   50   LEU LEU A . n 
A 1 51   GLU 51   51   51   GLU GLU A . n 
A 1 52   GLN 52   52   52   GLN GLN A . n 
A 1 53   LEU 53   53   53   LEU LEU A . n 
A 1 54   ALA 54   54   54   ALA ALA A . n 
A 1 55   GLU 55   55   55   GLU GLU A . n 
A 1 56   GLU 56   56   56   GLU GLU A . n 
A 1 57   ASP 57   57   57   ASP ASP A . n 
A 1 58   TYR 58   58   58   TYR TYR A . n 
A 1 59   LEU 59   59   59   LEU LEU A . n 
A 1 60   ILE 60   60   60   ILE ILE A . n 
A 1 61   SER 61   61   61   SER SER A . n 
A 1 62   LEU 62   62   62   LEU LEU A . n 
A 1 63   THR 63   63   63   THR THR A . n 
A 1 64   ASP 64   64   64   ASP ASP A . n 
A 1 65   ARG 65   65   65   ARG ARG A . n 
A 1 66   TRP 66   66   66   TRP TRP A . n 
A 1 67   LEU 67   67   67   LEU LEU A . n 
A 1 68   LEU 68   68   68   LEU LEU A . n 
A 1 69   SER 69   69   69   SER SER A . n 
A 1 70   TRP 70   70   70   TRP TRP A . n 
A 1 71   GLU 71   71   71   GLU GLU A . n 
A 1 72   ALA 72   72   72   ALA ALA A . n 
A 1 73   LEU 73   73   73   LEU LEU A . n 
A 1 74   TYR 74   74   74   TYR TYR A . n 
A 1 75   ARG 75   75   75   ARG ARG A . n 
A 1 76   LEU 76   76   76   LEU LEU A . n 
A 1 77   LEU 77   77   77   LEU LEU A . n 
A 1 78   GLU 78   78   78   GLU GLU A . n 
A 1 79   ASP 79   79   79   ASP ASP A . n 
A 1 80   GLU 80   80   80   GLU GLU A . n 
A 1 81   GLU 81   81   81   GLU GLU A . n 
A 1 82   HIS 82   82   82   HIS HIS A . n 
A 1 83   ALA 83   83   83   ALA ALA A . n 
A 1 84   SER 84   84   84   SER SER A . n 
A 1 85   SER 85   85   85   SER SER A . n 
A 1 86   LEU 86   86   86   LEU LEU A . n 
A 1 87   PRO 87   87   87   PRO PRO A . n 
A 1 88   LEU 88   88   88   LEU LEU A . n 
A 1 89   ILE 89   89   89   ILE ILE A . n 
A 1 90   GLY 90   90   90   GLY GLY A . n 
A 1 91   VAL 91   91   91   VAL VAL A . n 
A 1 92   PRO 92   92   92   PRO PRO A . n 
A 1 93   ASP 93   93   93   ASP ASP A . n 
A 1 94   ILE 94   94   94   ILE ILE A . n 
A 1 95   LEU 95   95   95   LEU LEU A . n 
A 1 96   PRO 96   96   96   PRO PRO A . n 
A 1 97   LEU 97   97   97   LEU LEU A . n 
A 1 98   ARG 98   98   98   ARG ARG A . n 
A 1 99   ALA 99   99   99   ALA ALA A . n 
A 1 100  SER 100  100  100  SER SER A . n 
A 1 101  LEU 101  101  101  LEU LEU A . n 
A 1 102  SER 102  102  102  SER SER A . n 
A 1 103  SER 103  103  103  SER SER A . n 
A 1 104  ARG 104  104  104  ARG ARG A . n 
A 1 105  GLY 105  105  105  GLY GLY A . n 
A 1 106  ALA 106  106  106  ALA ALA A . n 
A 1 107  LEU 107  107  107  LEU LEU A . n 
A 1 108  SER 108  108  108  SER SER A . n 
A 1 109  ASP 109  109  109  ASP ASP A . n 
A 1 110  SER 110  110  110  SER SER A . n 
A 1 111  ASP 111  111  111  ASP ASP A . n 
A 1 112  PHE 112  112  112  PHE PHE A . n 
A 1 113  ARG 113  113  113  ARG ARG A . n 
A 1 114  VAL 114  114  114  VAL VAL A . n 
A 1 115  TRP 115  115  115  TRP TRP A . n 
A 1 116  ILE 116  116  116  ILE ILE A . n 
A 1 117  ALA 117  117  117  ALA ALA A . n 
A 1 118  GLU 118  118  118  GLU GLU A . n 
A 1 119  TRP 119  119  119  TRP TRP A . n 
A 1 120  ALA 120  120  120  ALA ALA A . n 
A 1 121  THR 121  121  121  THR THR A . n 
A 1 122  PHE 122  122  122  PHE PHE A . n 
A 1 123  PRO 123  123  123  PRO PRO A . n 
A 1 124  ALA 124  124  124  ALA ALA A . n 
A 1 125  ARG 125  125  125  ARG ARG A . n 
A 1 126  LYS 126  126  126  LYS LYS A . n 
A 1 127  PRO 127  127  127  PRO PRO A . n 
A 1 128  ILE 128  128  128  ILE ILE A . n 
A 1 129  ARG 129  129  129  ARG ARG A . n 
A 1 130  PHE 130  130  130  PHE PHE A . n 
A 1 131  SER 131  131  131  SER SER A . n 
A 1 132  ARG 132  132  132  ARG ARG A . n 
A 1 133  THR 133  133  133  THR THR A . n 
A 1 134  GLY 134  134  134  GLY GLY A . n 
A 1 135  ALA 135  135  135  ALA ALA A . n 
A 1 136  ILE 136  136  136  ILE ILE A . n 
A 1 137  LEU 137  137  137  LEU LEU A . n 
A 1 138  THR 138  138  138  THR THR A . n 
A 1 139  HIS 139  139  139  HIS HIS A . n 
A 1 140  ASP 140  140  140  ASP ASP A . n 
A 1 141  ASN 141  141  141  ASN ASN A . n 
A 1 142  GLN 142  142  142  GLN GLN A . n 
A 1 143  GLN 143  143  143  GLN GLN A . n 
A 1 144  TYR 144  144  144  TYR TYR A . n 
A 1 145  LEU 145  145  145  LEU LEU A . n 
A 1 146  LEU 146  146  146  LEU LEU A . n 
A 1 147  SER 147  147  147  SER SER A . n 
A 1 148  ARG 148  148  148  ARG ARG A . n 
A 1 149  GLU 149  149  149  GLU GLU A . n 
A 1 150  ASN 150  150  150  ASN ASN A . n 
A 1 151  TRP 151  151  151  TRP TRP A . n 
A 1 152  ALA 152  152  152  ALA ALA A . n 
A 1 153  LEU 153  153  153  LEU LEU A . n 
A 1 154  LEU 154  154  154  LEU LEU A . n 
A 1 155  GLN 155  155  155  GLN GLN A . n 
A 1 156  ALA 156  156  156  ALA ALA A . n 
A 1 157  THR 157  157  157  THR THR A . n 
A 1 158  GLU 158  158  158  GLU GLU A . n 
A 1 159  GLN 159  159  159  GLN GLN A . n 
A 1 160  LEU 160  160  160  LEU LEU A . n 
A 1 161  SER 161  161  161  SER SER A . n 
A 1 162  ALA 162  162  162  ALA ALA A . n 
A 1 163  GLN 163  163  163  GLN GLN A . n 
A 1 164  GLN 164  164  164  GLN GLN A . n 
A 1 165  ILE 165  165  165  ILE ILE A . n 
A 1 166  GLN 166  166  166  GLN GLN A . n 
A 1 167  THR 167  167  167  THR THR A . n 
A 1 168  PRO 168  168  168  PRO PRO A . n 
A 1 169  GLY 169  169  169  GLY GLY A . n 
A 1 170  GLU 170  170  170  GLU GLU A . n 
A 1 171  THR 171  171  171  THR THR A . n 
A 1 172  THR 172  172  172  THR THR A . n 
A 1 173  ASN 173  173  173  ASN ASN A . n 
A 1 174  GLN 174  174  174  GLN GLN A . n 
A 1 175  LEU 175  175  175  LEU LEU A . n 
A 1 176  GLY 176  176  176  GLY GLY A . n 
A 1 177  TRP 177  177  177  TRP TRP A . n 
A 1 178  ALA 178  178  178  ALA ALA A . n 
A 1 179  ALA 179  179  179  ALA ALA A . n 
A 1 180  ILE 180  180  180  ILE ILE A . n 
A 1 181  ARG 181  181  181  ARG ARG A . n 
A 1 182  LYS 182  182  182  LYS LYS A . n 
A 1 183  CYS 183  183  183  CYS CYS A . n 
A 1 184  ALA 184  184  184  ALA ALA A . n 
A 1 185  LYS 185  185  185  LYS LYS A . n 
A 1 186  LEU 186  186  186  LEU LEU A . n 
A 1 187  ALA 187  187  187  ALA ALA A . n 
A 1 188  ALA 188  188  188  ALA ALA A . n 
A 1 189  ALA 189  189  189  ALA ALA A . n 
A 1 190  LYS 190  190  190  LYS LYS A . n 
A 1 191  PHE 191  191  191  PHE PHE A . n 
A 1 192  ASP 192  192  192  ASP ASP A . n 
A 1 193  ASP 193  193  193  ASP ASP A . n 
A 1 194  TYR 194  194  194  TYR TYR A . n 
A 1 195  LEU 195  195  195  LEU LEU A . n 
A 1 196  GLU 196  196  196  GLU GLU A . n 
A 1 197  LYS 197  197  197  LYS LYS A . n 
A 1 198  THR 198  198  198  THR THR A . n 
A 1 199  HIS 199  199  199  HIS HIS A . n 
A 1 200  VAL 200  200  200  VAL VAL A . n 
A 1 201  ILE 201  201  201  ILE ILE A . n 
A 1 202  LYS 202  202  202  LYS LYS A . n 
A 1 203  PRO 203  203  203  PRO PRO A . n 
A 1 204  THR 204  204  204  THR THR A . n 
A 1 205  SER 205  205  205  SER SER A . n 
A 1 206  LEU 206  206  206  LEU LEU A . n 
A 1 207  SER 207  207  207  SER SER A . n 
A 1 208  LEU 208  208  208  LEU LEU A . n 
A 1 209  ARG 209  209  209  ARG ARG A . n 
A 1 210  LEU 210  210  210  LEU LEU A . n 
A 1 211  ARG 211  211  211  ARG ARG A . n 
A 1 212  LYS 212  212  212  LYS LYS A . n 
A 1 213  ALA 213  213  213  ALA ALA A . n 
A 1 214  THR 214  214  214  THR THR A . n 
A 1 215  VAL 215  215  215  VAL VAL A . n 
A 1 216  ALA 216  216  216  ALA ALA A . n 
A 1 217  ASP 217  217  217  ASP ASP A . n 
A 1 218  THR 218  218  218  THR THR A . n 
A 1 219  ALA 219  219  219  ALA ALA A . n 
A 1 220  VAL 220  220  220  VAL VAL A . n 
A 1 221  ILE 221  221  221  ILE ILE A . n 
A 1 222  GLU 222  222  222  GLU GLU A . n 
A 1 223  ILE 223  223  223  ILE ILE A . n 
A 1 224  GLU 224  224  224  GLU GLU A . n 
A 1 225  PRO 225  225  225  PRO PRO A . n 
A 1 226  HIS 226  226  226  HIS HIS A . n 
A 1 227  PHE 227  227  227  PHE PHE A . n 
A 1 228  GLU 228  228  228  GLU GLU A . n 
A 1 229  ASP 229  229  229  ASP ASP A . n 
A 1 230  GLN 230  230  230  GLN GLN A . n 
A 1 231  PRO 231  231  231  PRO PRO A . n 
A 1 232  ALA 232  232  232  ALA ALA A . n 
A 1 233  ASN 233  233  233  ASN ASN A . n 
A 1 234  TRP 234  234  234  TRP TRP A . n 
A 1 235  LEU 235  235  235  LEU LEU A . n 
A 1 236  GLY 236  236  236  GLY GLY A . n 
A 1 237  SER 237  237  237  SER SER A . n 
A 1 238  PHE 238  238  238  PHE PHE A . n 
A 1 239  ASP 239  239  239  ASP ASP A . n 
A 1 240  LYS 240  240  240  LYS LYS A . n 
A 1 241  ASN 241  241  241  ASN ASN A . n 
A 1 242  LEU 242  242  242  LEU LEU A . n 
A 1 243  GLN 243  243  243  GLN GLN A . n 
A 1 244  VAL 244  244  244  VAL VAL A . n 
A 1 245  HIS 245  245  245  HIS HIS A . n 
A 1 246  ASP 246  246  246  ASP ASP A . n 
A 1 247  SER 247  247  247  SER SER A . n 
A 1 248  TYR 248  248  248  TYR TYR A . n 
A 1 249  ARG 249  249  249  ARG ARG A . n 
A 1 250  ILE 250  250  250  ILE ILE A . n 
A 1 251  PRO 251  251  251  PRO PRO A . n 
A 1 252  GLY 252  252  252  GLY GLY A . n 
A 1 253  GLU 253  253  253  GLU GLU A . n 
A 1 254  ASN 254  254  254  ASN ASN A . n 
A 1 255  GLY 255  255  255  GLY GLY A . n 
A 1 256  GLU 256  256  256  GLU GLU A . n 
A 1 257  LEU 257  257  257  LEU LEU A . n 
A 1 258  SER 258  258  258  SER SER A . n 
A 1 259  HIS 259  259  259  HIS HIS A . n 
A 1 260  VAL 260  260  260  VAL VAL A . n 
A 1 261  ILE 261  261  261  ILE ILE A . n 
A 1 262  ILE 262  262  262  ILE ILE A . n 
A 1 263  PRO 263  263  263  PRO PRO A . n 
A 1 264  PRO 264  264  264  PRO PRO A . n 
A 1 265  GLU 265  265  265  GLU GLU A . n 
A 1 266  VAL 266  266  266  VAL VAL A . n 
A 1 267  LYS 267  267  267  LYS LYS A . n 
A 1 268  GLU 268  268  268  GLU GLU A . n 
A 1 269  VAL 269  269  269  VAL VAL A . n 
A 1 270  LEU 270  270  270  LEU LEU A . n 
A 1 271  ASN 271  271  271  ASN ASN A . n 
A 1 272  SER 272  272  272  SER SER A . n 
A 1 273  ILE 273  273  273  ILE ILE A . n 
A 1 274  HIS 274  274  274  HIS HIS A . n 
A 1 275  SER 275  275  275  SER SER A . n 
A 1 276  ILE 276  276  276  ILE ILE A . n 
A 1 277  PRO 277  277  277  PRO PRO A . n 
A 1 278  GLY 278  278  278  GLY GLY A . n 
A 1 279  ARG 279  279  279  ARG ARG A . n 
A 1 280  ARG 280  280  280  ARG ARG A . n 
A 1 281  VAL 281  281  281  VAL VAL A . n 
A 1 282  ALA 282  282  282  ALA ALA A . n 
A 1 283  GLY 283  283  283  GLY GLY A . n 
A 1 284  SER 284  284  284  SER SER A . n 
A 1 285  GLU 285  285  285  GLU GLU A . n 
A 1 286  ALA 286  286  286  ALA ALA A . n 
A 1 287  LEU 287  287  287  LEU LEU A . n 
A 1 288  SER 288  288  288  SER SER A . n 
A 1 289  PHE 289  289  289  PHE PHE A . n 
A 1 290  VAL 290  290  290  VAL VAL A . n 
A 1 291  ARG 291  291  291  ARG ARG A . n 
A 1 292  ASN 292  292  292  ASN ASN A . n 
A 1 293  PRO 293  293  293  PRO PRO A . n 
A 1 294  TYR 294  294  294  TYR TYR A . n 
A 1 295  THR 295  295  295  THR THR A . n 
A 1 296  PHE 296  296  296  PHE PHE A . n 
A 1 297  LEU 297  297  297  LEU LEU A . n 
A 1 298  GLY 298  298  298  GLY GLY A . n 
A 1 299  GLU 299  299  299  GLU GLU A . n 
A 1 300  ASP 300  300  300  ASP ASP A . n 
A 1 301  ALA 301  301  301  ALA ALA A . n 
A 1 302  ALA 302  302  302  ALA ALA A . n 
A 1 303  SER 303  303  303  SER SER A . n 
A 1 304  VAL 304  304  304  VAL VAL A . n 
A 1 305  ILE 305  305  305  ILE ILE A . n 
A 1 306  ALA 306  306  306  ALA ALA A . n 
A 1 307  PRO 307  307  307  PRO PRO A . n 
A 1 308  GLU 308  308  308  GLU GLU A . n 
A 1 309  GLU 309  309  309  GLU GLU A . n 
A 1 310  HIS 310  310  310  HIS HIS A . n 
A 1 311  GLU 311  311  311  GLU GLU A . n 
A 1 312  GLN 312  312  312  GLN GLN A . n 
A 1 313  ALA 313  313  313  ALA ALA A . n 
A 1 314  LEU 314  314  314  LEU LEU A . n 
A 1 315  PHE 315  315  315  PHE PHE A . n 
A 1 316  ASP 316  316  316  ASP ASP A . n 
A 1 317  ALA 317  317  317  ALA ALA A . n 
A 1 318  ARG 318  318  318  ARG ARG A . n 
A 1 319  ILE 319  319  319  ILE ILE A . n 
A 1 320  PHE 320  320  320  PHE PHE A . n 
A 1 321  PHE 321  321  321  PHE PHE A . n 
A 1 322  HIS 322  322  322  HIS HIS A . n 
A 1 323  HIS 323  323  323  HIS HIS A . n 
A 1 324  PHE 324  324  324  PHE PHE A . n 
A 1 325  ARG 325  325  325  ARG ARG A . n 
A 1 326  LEU 326  326  326  LEU LEU A . n 
A 1 327  ILE 327  327  327  ILE ILE A . n 
A 1 328  PRO 328  328  328  PRO PRO A . n 
A 1 329  GLN 329  329  329  GLN GLN A . n 
A 1 330  LEU 330  330  330  LEU LEU A . n 
A 1 331  ASN 331  331  331  ASN ASN A . n 
A 1 332  THR 332  332  332  THR THR A . n 
A 1 333  GLU 333  333  333  GLU GLU A . n 
A 1 334  ASN 334  334  334  ASN ASN A . n 
A 1 335  LYS 335  335  335  LYS LYS A . n 
A 1 336  ILE 336  336  336  ILE ILE A . n 
A 1 337  THR 337  337  337  THR THR A . n 
A 1 338  GLU 338  338  338  GLU GLU A . n 
A 1 339  VAL 339  339  339  VAL VAL A . n 
A 1 340  THR 340  340  340  THR THR A . n 
A 1 341  LEU 341  341  341  LEU LEU A . n 
A 1 342  ILE 342  342  342  ILE ILE A . n 
A 1 343  LEU 343  343  343  LEU LEU A . n 
A 1 344  GLU 344  344  344  GLU GLU A . n 
A 1 345  PRO 345  345  345  PRO PRO A . n 
A 1 346  VAL 346  346  346  VAL VAL A . n 
A 1 347  SER 347  347  347  SER SER A . n 
A 1 348  PRO 348  348  348  PRO PRO A . n 
A 1 349  VAL 349  349  349  VAL VAL A . n 
A 1 350  PRO 350  350  350  PRO PRO A . n 
A 1 351  GLN 351  351  351  GLN GLN A . n 
A 1 352  PRO 352  352  352  PRO PRO A . n 
A 1 353  GLU 353  353  353  GLU GLU A . n 
A 1 354  ILE 354  354  354  ILE ILE A . n 
A 1 355  THR 355  355  355  THR THR A . n 
A 1 356  PHE 356  356  356  PHE PHE A . n 
A 1 357  VAL 357  357  357  VAL VAL A . n 
A 1 358  PHE 358  358  358  PHE PHE A . n 
A 1 359  SER 359  359  359  SER SER A . n 
A 1 360  ALA 360  360  360  ALA ALA A . n 
A 1 361  PRO 361  361  361  PRO PRO A . n 
A 1 362  TRP 362  362  362  TRP TRP A . n 
A 1 363  GLU 363  363  363  GLU GLU A . n 
A 1 364  LEU 364  364  364  LEU LEU A . n 
A 1 365  ASP 365  365  365  ASP ASP A . n 
A 1 366  LYS 366  366  366  LYS LYS A . n 
A 1 367  PHE 367  367  367  PHE PHE A . n 
A 1 368  ILE 368  368  368  ILE ILE A . n 
A 1 369  GLN 369  369  369  GLN GLN A . n 
A 1 370  GLN 370  370  370  GLN GLN A . n 
A 1 371  LEU 371  371  371  LEU LEU A . n 
A 1 372  GLY 372  372  372  GLY GLY A . n 
A 1 373  ILE 373  373  373  ILE ILE A . n 
A 1 374  SER 374  374  374  SER SER A . n 
A 1 375  VAL 375  375  375  VAL VAL A . n 
A 1 376  ALA 376  376  376  ALA ALA A . n 
A 1 377  ALA 377  377  377  ALA ALA A . n 
A 1 378  GLN 378  378  378  GLN GLN A . n 
A 1 379  MET 379  379  379  MET MET A . n 
A 1 380  PRO 380  380  380  PRO PRO A . n 
A 1 381  ALA 381  381  381  ALA ALA A . n 
A 1 382  GLY 382  382  382  GLY GLY A . n 
A 1 383  SER 383  383  383  SER SER A . n 
A 1 384  TRP 384  384  384  TRP TRP A . n 
A 1 385  GLN 385  385  385  GLN GLN A . n 
A 1 386  GLY 386  386  386  GLY GLY A . n 
A 1 387  TYR 387  387  387  TYR TYR A . n 
A 1 388  GLU 388  388  388  GLU GLU A . n 
A 1 389  LEU 389  389  389  LEU LEU A . n 
A 1 390  GLU 390  390  390  GLU GLU A . n 
A 1 391  LEU 391  391  391  LEU LEU A . n 
A 1 392  SER 392  392  392  SER SER A . n 
A 1 393  GLN 393  393  393  GLN GLN A . n 
A 1 394  PHE 394  394  394  PHE PHE A . n 
A 1 395  THR 395  395  395  THR THR A . n 
A 1 396  GLU 396  396  396  GLU GLU A . n 
A 1 397  GLN 397  397  397  GLN GLN A . n 
A 1 398  GLN 398  398  398  GLN GLN A . n 
A 1 399  TRP 399  399  399  TRP TRP A . n 
A 1 400  HIS 400  400  400  HIS HIS A . n 
A 1 401  ASP 401  401  401  ASP ASP A . n 
A 1 402  CYS 402  402  402  CYS CYS A . n 
A 1 403  GLN 403  403  403  GLN GLN A . n 
A 1 404  ALA 404  404  404  ALA ALA A . n 
A 1 405  LEU 405  405  405  LEU LEU A . n 
A 1 406  LEU 406  406  406  LEU LEU A . n 
A 1 407  THR 407  407  407  THR THR A . n 
A 1 408  ARG 408  408  408  ARG ARG A . n 
A 1 409  TRP 409  409  409  TRP TRP A . n 
A 1 410  GLN 410  410  410  GLN GLN A . n 
A 1 411  GLN 411  411  411  GLN GLN A . n 
A 1 412  GLU 412  412  412  GLU GLU A . n 
A 1 413  ILE 413  413  413  ILE ILE A . n 
A 1 414  GLU 414  414  414  GLU GLU A . n 
A 1 415  GLY 415  415  ?    ?   ?   A . n 
A 1 416  LYS 416  416  ?    ?   ?   A . n 
A 1 417  GLU 417  417  ?    ?   ?   A . n 
A 1 418  PHE 418  418  ?    ?   ?   A . n 
A 1 419  SER 419  419  ?    ?   ?   A . n 
A 1 420  ASP 420  420  ?    ?   ?   A . n 
A 1 421  VAL 421  421  ?    ?   ?   A . n 
A 1 422  LEU 422  422  ?    ?   ?   A . n 
A 1 423  ASP 423  423  ?    ?   ?   A . n 
A 1 424  ILE 424  424  ?    ?   ?   A . n 
A 1 425  ALA 425  425  ?    ?   ?   A . n 
A 1 426  LYS 426  426  ?    ?   ?   A . n 
A 1 427  TYR 427  427  ?    ?   ?   A . n 
A 1 428  GLY 428  428  ?    ?   ?   A . n 
A 1 429  ASP 429  429  ?    ?   ?   A . n 
A 1 430  ARG 430  430  ?    ?   ?   A . n 
A 1 431  VAL 431  431  ?    ?   ?   A . n 
A 1 432  ILE 432  432  ?    ?   ?   A . n 
A 1 433  GLY 433  433  ?    ?   ?   A . n 
A 1 434  ILE 434  434  ?    ?   ?   A . n 
A 1 435  GLY 435  435  ?    ?   ?   A . n 
A 1 436  GLU 436  436  ?    ?   ?   A . n 
A 1 437  PHE 437  437  ?    ?   ?   A . n 
A 1 438  GLU 438  438  ?    ?   ?   A . n 
A 1 439  LYS 439  439  ?    ?   ?   A . n 
A 1 440  ILE 440  440  ?    ?   ?   A . n 
A 1 441  SER 441  441  ?    ?   ?   A . n 
A 1 442  SER 442  442  ?    ?   ?   A . n 
A 1 443  PRO 443  443  ?    ?   ?   A . n 
A 1 444  TRP 444  444  ?    ?   ?   A . n 
A 1 445  LEU 445  445  ?    ?   ?   A . n 
A 1 446  THR 446  446  ?    ?   ?   A . n 
A 1 447  LYS 447  447  ?    ?   ?   A . n 
A 1 448  ALA 448  448  ?    ?   ?   A . n 
A 1 449  GLN 449  449  ?    ?   ?   A . n 
A 1 450  SER 450  450  ?    ?   ?   A . n 
A 1 451  GLU 451  451  ?    ?   ?   A . n 
A 1 452  ASN 452  452  ?    ?   ?   A . n 
A 1 453  TRP 453  453  ?    ?   ?   A . n 
A 1 454  LEU 454  454  ?    ?   ?   A . n 
A 1 455  PRO 455  455  ?    ?   ?   A . n 
A 1 456  ASP 456  456  ?    ?   ?   A . n 
A 1 457  GLY 457  457  ?    ?   ?   A . n 
A 1 458  ILE 458  458  ?    ?   ?   A . n 
A 1 459  ASP 459  459  ?    ?   ?   A . n 
A 1 460  PHE 460  460  ?    ?   ?   A . n 
A 1 461  SER 461  461  ?    ?   ?   A . n 
A 1 462  ALA 462  462  ?    ?   ?   A . n 
A 1 463  PHE 463  463  ?    ?   ?   A . n 
A 1 464  SER 464  464  ?    ?   ?   A . n 
A 1 465  ILE 465  465  ?    ?   ?   A . n 
A 1 466  GLU 466  466  ?    ?   ?   A . n 
A 1 467  THR 467  467  ?    ?   ?   A . n 
A 1 468  LEU 468  468  ?    ?   ?   A . n 
A 1 469  SER 469  469  ?    ?   ?   A . n 
A 1 470  GLY 470  470  ?    ?   ?   A . n 
A 1 471  TRP 471  471  ?    ?   ?   A . n 
A 1 472  GLN 472  472  ?    ?   ?   A . n 
A 1 473  PRO 473  473  ?    ?   ?   A . n 
A 1 474  GLU 474  474  ?    ?   ?   A . n 
A 1 475  ASN 475  475  ?    ?   ?   A . n 
A 1 476  PRO 476  476  ?    ?   ?   A . n 
A 1 477  LEU 477  477  ?    ?   ?   A . n 
A 1 478  HIS 478  478  ?    ?   ?   A . n 
A 1 479  PHE 479  479  ?    ?   ?   A . n 
A 1 480  ASP 480  480  ?    ?   ?   A . n 
A 1 481  GLU 481  481  ?    ?   ?   A . n 
A 1 482  LEU 482  482  ?    ?   ?   A . n 
A 1 483  GLN 483  483  ?    ?   ?   A . n 
A 1 484  GLU 484  484  ?    ?   ?   A . n 
A 1 485  ILE 485  485  ?    ?   ?   A . n 
A 1 486  ILE 486  486  ?    ?   ?   A . n 
A 1 487  THR 487  487  ?    ?   ?   A . n 
A 1 488  GLN 488  488  ?    ?   ?   A . n 
A 1 489  ALA 489  489  ?    ?   ?   A . n 
A 1 490  GLU 490  490  ?    ?   ?   A . n 
A 1 491  ALA 491  491  ?    ?   ?   A . n 
A 1 492  ALA 492  492  ?    ?   ?   A . n 
A 1 493  GLY 493  493  ?    ?   ?   A . n 
A 1 494  GLU 494  494  ?    ?   ?   A . n 
A 1 495  THR 495  495  ?    ?   ?   A . n 
A 1 496  TYR 496  496  ?    ?   ?   A . n 
A 1 497  ILE 497  497  ?    ?   ?   A . n 
A 1 498  THR 498  498  ?    ?   ?   A . n 
A 1 499  THR 499  499  ?    ?   ?   A . n 
A 1 500  PRO 500  500  ?    ?   ?   A . n 
A 1 501  TRP 501  501  ?    ?   ?   A . n 
A 1 502  ASN 502  502  ?    ?   ?   A . n 
A 1 503  ASP 503  503  ?    ?   ?   A . n 
A 1 504  SER 504  504  ?    ?   ?   A . n 
A 1 505  GLN 505  505  ?    ?   ?   A . n 
A 1 506  LEU 506  506  ?    ?   ?   A . n 
A 1 507  PRO 507  507  ?    ?   ?   A . n 
A 1 508  LEU 508  508  ?    ?   ?   A . n 
A 1 509  ASP 509  509  ?    ?   ?   A . n 
A 1 510  ALA 510  510  ?    ?   ?   A . n 
A 1 511  ALA 511  511  ?    ?   ?   A . n 
A 1 512  LYS 512  512  ?    ?   ?   A . n 
A 1 513  THR 513  513  ?    ?   ?   A . n 
A 1 514  PHE 514  514  ?    ?   ?   A . n 
A 1 515  SER 515  515  ?    ?   ?   A . n 
A 1 516  LYS 516  516  ?    ?   ?   A . n 
A 1 517  ASN 517  517  ?    ?   ?   A . n 
A 1 518  TRP 518  518  ?    ?   ?   A . n 
A 1 519  GLU 519  519  ?    ?   ?   A . n 
A 1 520  LYS 520  520  ?    ?   ?   A . n 
A 1 521  GLN 521  521  ?    ?   ?   A . n 
A 1 522  GLN 522  522  ?    ?   ?   A . n 
A 1 523  ILE 523  523  ?    ?   ?   A . n 
A 1 524  THR 524  524  ?    ?   ?   A . n 
A 1 525  ALA 525  525  ?    ?   ?   A . n 
A 1 526  ASN 526  526  ?    ?   ?   A . n 
A 1 527  GLU 527  527  ?    ?   ?   A . n 
A 1 528  TYR 528  528  ?    ?   ?   A . n 
A 1 529  GLN 529  529  ?    ?   ?   A . n 
A 1 530  GLY 530  530  ?    ?   ?   A . n 
A 1 531  ASN 531  531  ?    ?   ?   A . n 
A 1 532  VAL 532  532  ?    ?   ?   A . n 
A 1 533  ALA 533  533  ?    ?   ?   A . n 
A 1 534  ASP 534  534  ?    ?   ?   A . n 
A 1 535  LYS 535  535  ?    ?   ?   A . n 
A 1 536  THR 536  536  ?    ?   ?   A . n 
A 1 537  ALA 537  537  ?    ?   ?   A . n 
A 1 538  ARG 538  538  ?    ?   ?   A . n 
A 1 539  ALA 539  539  ?    ?   ?   A . n 
A 1 540  VAL 540  540  ?    ?   ?   A . n 
A 1 541  LEU 541  541  ?    ?   ?   A . n 
A 1 542  LYS 542  542  ?    ?   ?   A . n 
A 1 543  ILE 543  543  ?    ?   ?   A . n 
A 1 544  GLU 544  544  ?    ?   ?   A . n 
A 1 545  GLN 545  545  ?    ?   ?   A . n 
A 1 546  ASN 546  546  ?    ?   ?   A . n 
A 1 547  ILE 547  547  ?    ?   ?   A . n 
A 1 548  GLU 548  548  ?    ?   ?   A . n 
A 1 549  GLU 549  549  ?    ?   ?   A . n 
A 1 550  THR 550  550  ?    ?   ?   A . n 
A 1 551  ALA 551  551  ?    ?   ?   A . n 
A 1 552  TYR 552  552  ?    ?   ?   A . n 
A 1 553  ILE 553  553  ?    ?   ?   A . n 
A 1 554  LYS 554  554  ?    ?   ?   A . n 
A 1 555  GLN 555  555  ?    ?   ?   A . n 
A 1 556  ARG 556  556  ?    ?   ?   A . n 
A 1 557  ARG 557  557  ?    ?   ?   A . n 
A 1 558  ASN 558  558  ?    ?   ?   A . n 
A 1 559  SER 559  559  ?    ?   ?   A . n 
A 1 560  LEU 560  560  ?    ?   ?   A . n 
A 1 561  LEU 561  561  ?    ?   ?   A . n 
A 1 562  ASN 562  562  ?    ?   ?   A . n 
A 1 563  ALA 563  563  ?    ?   ?   A . n 
A 1 564  ARG 564  564  ?    ?   ?   A . n 
A 1 565  HIS 565  565  ?    ?   ?   A . n 
A 1 566  ALA 566  566  566  ALA ALA A . n 
A 1 567  GLU 567  567  567  GLU GLU A . n 
A 1 568  PRO 568  568  568  PRO PRO A . n 
A 1 569  GLU 569  569  569  GLU GLU A . n 
A 1 570  ILE 570  570  570  ILE ILE A . n 
A 1 571  PRO 571  571  571  PRO PRO A . n 
A 1 572  LEU 572  572  572  LEU LEU A . n 
A 1 573  SER 573  573  573  SER SER A . n 
A 1 574  LEU 574  574  574  LEU LEU A . n 
A 1 575  LYS 575  575  575  LYS LYS A . n 
A 1 576  GLU 576  576  576  GLU GLU A . n 
A 1 577  HIS 577  577  577  HIS HIS A . n 
A 1 578  ILE 578  578  578  ILE ILE A . n 
A 1 579  ARG 579  579  579  ARG ARG A . n 
A 1 580  LEU 580  580  580  LEU LEU A . n 
A 1 581  LYS 581  581  581  LYS LYS A . n 
A 1 582  ASP 582  582  582  ASP ASP A . n 
A 1 583  HIS 583  583  583  HIS HIS A . n 
A 1 584  GLN 584  584  584  GLN GLN A . n 
A 1 585  ARG 585  585  585  ARG ARG A . n 
A 1 586  GLU 586  586  586  GLU GLU A . n 
A 1 587  GLY 587  587  587  GLY GLY A . n 
A 1 588  VAL 588  588  588  VAL VAL A . n 
A 1 589  ALA 589  589  589  ALA ALA A . n 
A 1 590  TRP 590  590  590  TRP TRP A . n 
A 1 591  LEU 591  591  591  LEU LEU A . n 
A 1 592  GLN 592  592  592  GLN GLN A . n 
A 1 593  GLN 593  593  593  GLN GLN A . n 
A 1 594  LEU 594  594  594  LEU LEU A . n 
A 1 595  PHE 595  595  595  PHE PHE A . n 
A 1 596  LEU 596  596  596  LEU LEU A . n 
A 1 597  ARG 597  597  597  ARG ARG A . n 
A 1 598  SER 598  598  598  SER SER A . n 
A 1 599  PRO 599  599  599  PRO PRO A . n 
A 1 600  GLU 600  600  600  GLU GLU A . n 
A 1 601  GLU 601  601  601  GLU GLU A . n 
A 1 602  THR 602  602  602  THR THR A . n 
A 1 603  ALA 603  603  603  ALA ALA A . n 
A 1 604  GLY 604  604  604  GLY GLY A . n 
A 1 605  CYS 605  605  605  CYS CYS A . n 
A 1 606  LEU 606  606  606  LEU LEU A . n 
A 1 607  LEU 607  607  607  LEU LEU A . n 
A 1 608  ALA 608  608  608  ALA ALA A . n 
A 1 609  ASP 609  609  609  ASP ASP A . n 
A 1 610  ASP 610  610  610  ASP ASP A . n 
A 1 611  MET 611  611  611  MET MET A . n 
A 1 612  GLY 612  612  612  GLY GLY A . n 
A 1 613  LEU 613  613  613  LEU LEU A . n 
A 1 614  GLY 614  614  614  GLY GLY A . n 
A 1 615  LYS 615  615  615  LYS LYS A . n 
A 1 616  THR 616  616  616  THR THR A . n 
A 1 617  LEU 617  617  617  LEU LEU A . n 
A 1 618  GLN 618  618  618  GLN GLN A . n 
A 1 619  ILE 619  619  619  ILE ILE A . n 
A 1 620  LEU 620  620  620  LEU LEU A . n 
A 1 621  SER 621  621  621  SER SER A . n 
A 1 622  PHE 622  622  622  PHE PHE A . n 
A 1 623  LEU 623  623  623  LEU LEU A . n 
A 1 624  VAL 624  624  624  VAL VAL A . n 
A 1 625  TRP 625  625  625  TRP TRP A . n 
A 1 626  PHE 626  626  626  PHE PHE A . n 
A 1 627  ILE 627  627  627  ILE ILE A . n 
A 1 628  GLU 628  628  628  GLU GLU A . n 
A 1 629  LYS 629  629  629  LYS LYS A . n 
A 1 630  PHE 630  630  630  PHE PHE A . n 
A 1 631  PRO 631  631  631  PRO PRO A . n 
A 1 632  GLN 632  632  632  GLN GLN A . n 
A 1 633  GLU 633  633  633  GLU GLU A . n 
A 1 634  PRO 634  634  634  PRO PRO A . n 
A 1 635  PRO 635  635  635  PRO PRO A . n 
A 1 636  ASN 636  636  636  ASN ASN A . n 
A 1 637  LEU 637  637  637  LEU LEU A . n 
A 1 638  ILE 638  638  638  ILE ILE A . n 
A 1 639  VAL 639  639  639  VAL VAL A . n 
A 1 640  ALA 640  640  640  ALA ALA A . n 
A 1 641  PRO 641  641  641  PRO PRO A . n 
A 1 642  VAL 642  642  642  VAL VAL A . n 
A 1 643  SER 643  643  643  SER SER A . n 
A 1 644  LEU 644  644  644  LEU LEU A . n 
A 1 645  LEU 645  645  645  LEU LEU A . n 
A 1 646  ASP 646  646  646  ASP ASP A . n 
A 1 647  ASN 647  647  647  ASN ASN A . n 
A 1 648  TRP 648  648  648  TRP TRP A . n 
A 1 649  GLU 649  649  649  GLU GLU A . n 
A 1 650  ARG 650  650  650  ARG ARG A . n 
A 1 651  GLU 651  651  651  GLU GLU A . n 
A 1 652  LEU 652  652  652  LEU LEU A . n 
A 1 653  ASN 653  653  653  ASN ASN A . n 
A 1 654  ASN 654  654  654  ASN ASN A . n 
A 1 655  PHE 655  655  655  PHE PHE A . n 
A 1 656  PHE 656  656  656  PHE PHE A . n 
A 1 657  TYR 657  657  657  TYR TYR A . n 
A 1 658  THR 658  658  658  THR THR A . n 
A 1 659  ALA 659  659  659  ALA ALA A . n 
A 1 660  GLY 660  660  660  GLY GLY A . n 
A 1 661  ILE 661  661  661  ILE ILE A . n 
A 1 662  PRO 662  662  662  PRO PRO A . n 
A 1 663  VAL 663  663  663  VAL VAL A . n 
A 1 664  LEU 664  664  664  LEU LEU A . n 
A 1 665  LYS 665  665  665  LYS LYS A . n 
A 1 666  LEU 666  666  666  LEU LEU A . n 
A 1 667  TYR 667  667  667  TYR TYR A . n 
A 1 668  GLY 668  668  668  GLY GLY A . n 
A 1 669  GLU 669  669  669  GLU GLU A . n 
A 1 670  THR 670  670  670  THR THR A . n 
A 1 671  ILE 671  671  671  ILE ILE A . n 
A 1 672  LYS 672  672  672  LYS LYS A . n 
A 1 673  ALA 673  673  673  ALA ALA A . n 
A 1 674  VAL 674  674  674  VAL VAL A . n 
A 1 675  LYS 675  675  675  LYS LYS A . n 
A 1 676  TYR 676  676  676  TYR TYR A . n 
A 1 677  PRO 677  677  677  PRO PRO A . n 
A 1 678  LYS 678  678  678  LYS LYS A . n 
A 1 679  GLN 679  679  679  GLN GLN A . n 
A 1 680  ALA 680  680  680  ALA ALA A . n 
A 1 681  ILE 681  681  681  ILE ILE A . n 
A 1 682  PRO 682  682  682  PRO PRO A . n 
A 1 683  ALA 683  683  683  ALA ALA A . n 
A 1 684  HIS 684  684  684  HIS HIS A . n 
A 1 685  LEU 685  685  685  LEU LEU A . n 
A 1 686  GLN 686  686  686  GLN GLN A . n 
A 1 687  SER 687  687  687  SER SER A . n 
A 1 688  LYS 688  688  688  LYS LYS A . n 
A 1 689  GLY 689  689  689  GLY GLY A . n 
A 1 690  ILE 690  690  690  ILE ILE A . n 
A 1 691  LYS 691  691  691  LYS LYS A . n 
A 1 692  ASN 692  692  692  ASN ASN A . n 
A 1 693  LEU 693  693  693  LEU LEU A . n 
A 1 694  LEU 694  694  694  LEU LEU A . n 
A 1 695  LYS 695  695  695  LYS LYS A . n 
A 1 696  PRO 696  696  696  PRO PRO A . n 
A 1 697  GLY 697  697  697  GLY GLY A . n 
A 1 698  TRP 698  698  698  TRP TRP A . n 
A 1 699  GLN 699  699  699  GLN GLN A . n 
A 1 700  GLY 700  700  700  GLY GLY A . n 
A 1 701  GLU 701  701  701  GLU GLU A . n 
A 1 702  ALA 702  702  702  ALA ALA A . n 
A 1 703  LYS 703  703  703  LYS LYS A . n 
A 1 704  ILE 704  704  704  ILE ILE A . n 
A 1 705  ILE 705  705  705  ILE ILE A . n 
A 1 706  LEU 706  706  706  LEU LEU A . n 
A 1 707  THR 707  707  707  THR THR A . n 
A 1 708  THR 708  708  708  THR THR A . n 
A 1 709  TYR 709  709  709  TYR TYR A . n 
A 1 710  GLU 710  710  710  GLU GLU A . n 
A 1 711  THR 711  711  711  THR THR A . n 
A 1 712  LEU 712  712  712  LEU LEU A . n 
A 1 713  ARG 713  713  713  ARG ARG A . n 
A 1 714  ASP 714  714  714  ASP ASP A . n 
A 1 715  GLN 715  715  715  GLN GLN A . n 
A 1 716  GLU 716  716  716  GLU GLU A . n 
A 1 717  PHE 717  717  717  PHE PHE A . n 
A 1 718  SER 718  718  718  SER SER A . n 
A 1 719  LEU 719  719  719  LEU LEU A . n 
A 1 720  ALA 720  720  720  ALA ALA A . n 
A 1 721  ARG 721  721  721  ARG ARG A . n 
A 1 722  GLN 722  722  722  GLN GLN A . n 
A 1 723  PRO 723  723  723  PRO PRO A . n 
A 1 724  TRP 724  724  724  TRP TRP A . n 
A 1 725  SER 725  725  725  SER SER A . n 
A 1 726  ILE 726  726  726  ILE ILE A . n 
A 1 727  MET 727  727  727  MET MET A . n 
A 1 728  VAL 728  728  728  VAL VAL A . n 
A 1 729  CYS 729  729  729  CYS CYS A . n 
A 1 730  ASP 730  730  730  ASP ASP A . n 
A 1 731  GLU 731  731  731  GLU GLU A . n 
A 1 732  ALA 732  732  732  ALA ALA A . n 
A 1 733  GLN 733  733  733  GLN GLN A . n 
A 1 734  LYS 734  734  734  LYS LYS A . n 
A 1 735  ILE 735  735  735  ILE ILE A . n 
A 1 736  LYS 736  736  736  LYS LYS A . n 
A 1 737  ASN 737  737  737  ASN ASN A . n 
A 1 738  PRO 738  738  738  PRO PRO A . n 
A 1 739  ALA 739  739  739  ALA ALA A . n 
A 1 740  ALA 740  740  740  ALA ALA A . n 
A 1 741  LEU 741  741  741  LEU LEU A . n 
A 1 742  ILE 742  742  742  ILE ILE A . n 
A 1 743  THR 743  743  743  THR THR A . n 
A 1 744  HIS 744  744  744  HIS HIS A . n 
A 1 745  ALA 745  745  745  ALA ALA A . n 
A 1 746  ALA 746  746  746  ALA ALA A . n 
A 1 747  ASN 747  747  747  ASN ASN A . n 
A 1 748  ALA 748  748  748  ALA ALA A . n 
A 1 749  VAL 749  749  749  VAL VAL A . n 
A 1 750  GLN 750  750  750  GLN GLN A . n 
A 1 751  ALA 751  751  751  ALA ALA A . n 
A 1 752  ARG 752  752  752  ARG ARG A . n 
A 1 753  PHE 753  753  753  PHE PHE A . n 
A 1 754  LYS 754  754  754  LYS LYS A . n 
A 1 755  VAL 755  755  755  VAL VAL A . n 
A 1 756  ALA 756  756  756  ALA ALA A . n 
A 1 757  CYS 757  757  757  CYS CYS A . n 
A 1 758  THR 758  758  758  THR THR A . n 
A 1 759  GLY 759  759  759  GLY GLY A . n 
A 1 760  THR 760  760  760  THR THR A . n 
A 1 761  PRO 761  761  761  PRO PRO A . n 
A 1 762  VAL 762  762  762  VAL VAL A . n 
A 1 763  GLU 763  763  763  GLU GLU A . n 
A 1 764  ASN 764  764  764  ASN ASN A . n 
A 1 765  THR 765  765  765  THR THR A . n 
A 1 766  LEU 766  766  766  LEU LEU A . n 
A 1 767  VAL 767  767  767  VAL VAL A . n 
A 1 768  ASP 768  768  768  ASP ASP A . n 
A 1 769  LEU 769  769  769  LEU LEU A . n 
A 1 770  TRP 770  770  770  TRP TRP A . n 
A 1 771  SER 771  771  771  SER SER A . n 
A 1 772  LEU 772  772  772  LEU LEU A . n 
A 1 773  PHE 773  773  773  PHE PHE A . n 
A 1 774  ASP 774  774  774  ASP ASP A . n 
A 1 775  PHE 775  775  775  PHE PHE A . n 
A 1 776  ALA 776  776  776  ALA ALA A . n 
A 1 777  GLN 777  777  777  GLN GLN A . n 
A 1 778  PRO 778  778  778  PRO PRO A . n 
A 1 779  GLY 779  779  779  GLY GLY A . n 
A 1 780  LEU 780  780  780  LEU LEU A . n 
A 1 781  LEU 781  781  781  LEU LEU A . n 
A 1 782  GLY 782  782  782  GLY GLY A . n 
A 1 783  ALA 783  783  783  ALA ALA A . n 
A 1 784  LEU 784  784  784  LEU LEU A . n 
A 1 785  ASN 785  785  785  ASN ASN A . n 
A 1 786  GLU 786  786  786  GLU GLU A . n 
A 1 787  PHE 787  787  787  PHE PHE A . n 
A 1 788  GLY 788  788  788  GLY GLY A . n 
A 1 789  LYS 789  789  789  LYS LYS A . n 
A 1 790  GLN 790  790  790  GLN GLN A . n 
A 1 791  TYR 791  791  791  TYR TYR A . n 
A 1 792  VAL 792  792  792  VAL VAL A . n 
A 1 793  ARG 793  793  793  ARG ARG A . n 
A 1 794  PRO 794  794  794  PRO PRO A . n 
A 1 795  ILE 795  795  795  ILE ILE A . n 
A 1 796  GLU 796  796  796  GLU GLU A . n 
A 1 797  ASN 797  797  ?    ?   ?   A . n 
A 1 798  GLU 798  798  ?    ?   ?   A . n 
A 1 799  ASP 799  799  ?    ?   ?   A . n 
A 1 800  GLY 800  800  ?    ?   ?   A . n 
A 1 801  ARG 801  801  ?    ?   ?   A . n 
A 1 802  ASP 802  802  ?    ?   ?   A . n 
A 1 803  THR 803  803  803  THR THR A . n 
A 1 804  GLU 804  804  804  GLU GLU A . n 
A 1 805  ARG 805  805  805  ARG ARG A . n 
A 1 806  LEU 806  806  806  LEU LEU A . n 
A 1 807  GLU 807  807  807  GLU GLU A . n 
A 1 808  SER 808  808  808  SER SER A . n 
A 1 809  LEU 809  809  809  LEU LEU A . n 
A 1 810  ARG 810  810  810  ARG ARG A . n 
A 1 811  ALA 811  811  811  ALA ALA A . n 
A 1 812  LEU 812  812  812  LEU LEU A . n 
A 1 813  ILE 813  813  813  ILE ILE A . n 
A 1 814  GLU 814  814  814  GLU GLU A . n 
A 1 815  PRO 815  815  815  PRO PRO A . n 
A 1 816  GLN 816  816  816  GLN GLN A . n 
A 1 817  THR 817  817  817  THR THR A . n 
A 1 818  LEU 818  818  818  LEU LEU A . n 
A 1 819  ARG 819  819  819  ARG ARG A . n 
A 1 820  ARG 820  820  820  ARG ARG A . n 
A 1 821  THR 821  821  821  THR THR A . n 
A 1 822  LYS 822  822  822  LYS LYS A . n 
A 1 823  GLU 823  823  823  GLU GLU A . n 
A 1 824  GLU 824  824  824  GLU GLU A . n 
A 1 825  VAL 825  825  825  VAL VAL A . n 
A 1 826  ALA 826  826  826  ALA ALA A . n 
A 1 827  ARG 827  827  827  ARG ARG A . n 
A 1 828  ASP 828  828  828  ASP ASP A . n 
A 1 829  LEU 829  829  829  LEU LEU A . n 
A 1 830  PRO 830  830  830  PRO PRO A . n 
A 1 831  GLN 831  831  831  GLN GLN A . n 
A 1 832  LYS 832  832  832  LYS LYS A . n 
A 1 833  ILE 833  833  833  ILE ILE A . n 
A 1 834  GLU 834  834  834  GLU GLU A . n 
A 1 835  VAL 835  835  835  VAL VAL A . n 
A 1 836  GLU 836  836  836  GLU GLU A . n 
A 1 837  SER 837  837  837  SER SER A . n 
A 1 838  CYS 838  838  838  CYS CYS A . n 
A 1 839  LYS 839  839  839  LYS LYS A . n 
A 1 840  GLN 840  840  840  GLN GLN A . n 
A 1 841  LEU 841  841  841  LEU LEU A . n 
A 1 842  THR 842  842  842  THR THR A . n 
A 1 843  LEU 843  843  843  LEU LEU A . n 
A 1 844  SER 844  844  844  SER SER A . n 
A 1 845  GLY 845  845  845  GLY GLY A . n 
A 1 846  VAL 846  846  846  VAL VAL A . n 
A 1 847  GLN 847  847  847  GLN GLN A . n 
A 1 848  LYS 848  848  848  LYS LYS A . n 
A 1 849  GLN 849  849  849  GLN GLN A . n 
A 1 850  LEU 850  850  850  LEU LEU A . n 
A 1 851  TYR 851  851  851  TYR GLY A . n 
A 1 852  LEU 852  852  852  LEU LEU A . n 
A 1 853  SER 853  853  853  SER SER A . n 
A 1 854  SER 854  854  854  SER SER A . n 
A 1 855  VAL 855  855  855  VAL VAL A . n 
A 1 856  ALA 856  856  856  ALA ALA A . n 
A 1 857  ASN 857  857  857  ASN ASN A . n 
A 1 858  TRP 858  858  858  TRP TRP A . n 
A 1 859  GLN 859  859  859  GLN GLN A . n 
A 1 860  GLN 860  860  860  GLN GLN A . n 
A 1 861  GLN 861  861  861  GLN GLN A . n 
A 1 862  GLN 862  862  862  GLN GLN A . n 
A 1 863  ALA 863  863  863  ALA ALA A . n 
A 1 864  LEU 864  864  864  LEU LEU A . n 
A 1 865  ARG 865  865  ?    ?   ?   A . n 
A 1 866  GLU 866  866  ?    ?   ?   A . n 
A 1 867  GLY 867  867  ?    ?   ?   A . n 
A 1 868  MET 868  868  ?    ?   ?   A . n 
A 1 869  GLN 869  869  ?    ?   ?   A . n 
A 1 870  GLN 870  870  ?    ?   ?   A . n 
A 1 871  ALA 871  871  ?    ?   ?   A . n 
A 1 872  GLY 872  872  ?    ?   ?   A . n 
A 1 873  THR 873  873  ?    ?   ?   A . n 
A 1 874  GLY 874  874  874  GLY GLY A . n 
A 1 875  MET 875  875  875  MET MET A . n 
A 1 876  LEU 876  876  876  LEU LEU A . n 
A 1 877  GLY 877  877  877  GLY GLY A . n 
A 1 878  LEU 878  878  878  LEU LEU A . n 
A 1 879  LEU 879  879  879  LEU LEU A . n 
A 1 880  HIS 880  880  880  HIS HIS A . n 
A 1 881  ARG 881  881  881  ARG ARG A . n 
A 1 882  LEU 882  882  882  LEU LEU A . n 
A 1 883  LYS 883  883  883  LYS LYS A . n 
A 1 884  LEU 884  884  884  LEU LEU A . n 
A 1 885  ILE 885  885  885  ILE ILE A . n 
A 1 886  CYS 886  886  886  CYS CYS A . n 
A 1 887  ALA 887  887  887  ALA ALA A . n 
A 1 888  HIS 888  888  888  HIS HIS A . n 
A 1 889  PRO 889  889  889  PRO PRO A . n 
A 1 890  ALA 890  890  890  ALA ALA A . n 
A 1 891  ILE 891  891  891  ILE ILE A . n 
A 1 892  VAL 892  892  892  VAL VAL A . n 
A 1 893  ASN 893  893  893  ASN ASN A . n 
A 1 894  PRO 894  894  894  PRO PRO A . n 
A 1 895  GLU 895  895  895  GLU GLU A . n 
A 1 896  PRO 896  896  896  PRO PRO A . n 
A 1 897  ARG 897  897  897  ARG ARG A . n 
A 1 898  PHE 898  898  898  PHE PHE A . n 
A 1 899  ARG 899  899  899  ARG ARG A . n 
A 1 900  ASP 900  900  900  ASP ASP A . n 
A 1 901  ASN 901  901  901  ASN ASN A . n 
A 1 902  SER 902  902  902  SER SER A . n 
A 1 903  PRO 903  903  903  PRO PRO A . n 
A 1 904  LYS 904  904  904  LYS LYS A . n 
A 1 905  LEU 905  905  905  LEU LEU A . n 
A 1 906  ASN 906  906  906  ASN ASN A . n 
A 1 907  TRP 907  907  907  TRP TRP A . n 
A 1 908  LEU 908  908  908  LEU LEU A . n 
A 1 909  LEU 909  909  909  LEU LEU A . n 
A 1 910  LYS 910  910  910  LYS LYS A . n 
A 1 911  ILE 911  911  911  ILE ILE A . n 
A 1 912  LEU 912  912  912  LEU LEU A . n 
A 1 913  ALA 913  913  913  ALA ALA A . n 
A 1 914  GLU 914  914  914  GLU GLU A . n 
A 1 915  ILE 915  915  915  ILE ILE A . n 
A 1 916  LYS 916  916  916  LYS LYS A . n 
A 1 917  HIS 917  917  917  HIS HIS A . n 
A 1 918  THR 918  918  918  THR THR A . n 
A 1 919  SER 919  919  919  SER SER A . n 
A 1 920  LYS 920  920  920  LYS LYS A . n 
A 1 921  ASP 921  921  921  ASP ASP A . n 
A 1 922  LYS 922  922  922  LYS LYS A . n 
A 1 923  VAL 923  923  923  VAL VAL A . n 
A 1 924  ILE 924  924  924  ILE ILE A . n 
A 1 925  ILE 925  925  925  ILE ILE A . n 
A 1 926  PHE 926  926  926  PHE PHE A . n 
A 1 927  THR 927  927  927  THR THR A . n 
A 1 928  GLU 928  928  928  GLU GLU A . n 
A 1 929  LEU 929  929  929  LEU LEU A . n 
A 1 930  ARG 930  930  930  ARG ARG A . n 
A 1 931  ASP 931  931  931  ASP ASP A . n 
A 1 932  LEU 932  932  932  LEU LEU A . n 
A 1 933  GLN 933  933  933  GLN GLN A . n 
A 1 934  ARG 934  934  934  ARG ARG A . n 
A 1 935  GLU 935  935  935  GLU GLU A . n 
A 1 936  LEU 936  936  936  LEU LEU A . n 
A 1 937  GLN 937  937  937  GLN GLN A . n 
A 1 938  HIS 938  938  938  HIS HIS A . n 
A 1 939  ALA 939  939  939  ALA ALA A . n 
A 1 940  ILE 940  940  940  ILE ILE A . n 
A 1 941  HIS 941  941  941  HIS HIS A . n 
A 1 942  GLN 942  942  942  GLN GLN A . n 
A 1 943  ASN 943  943  943  ASN ASN A . n 
A 1 944  PHE 944  944  944  PHE PHE A . n 
A 1 945  GLY 945  945  945  GLY GLY A . n 
A 1 946  PHE 946  946  946  PHE PHE A . n 
A 1 947  ARG 947  947  947  ARG ARG A . n 
A 1 948  PRO 948  948  948  PRO PRO A . n 
A 1 949  VAL 949  949  949  VAL VAL A . n 
A 1 950  ILE 950  950  950  ILE ILE A . n 
A 1 951  ILE 951  951  951  ILE ILE A . n 
A 1 952  ASN 952  952  952  ASN ASN A . n 
A 1 953  GLY 953  953  953  GLY GLY A . n 
A 1 954  ASP 954  954  954  ASP ASP A . n 
A 1 955  SER 955  955  955  SER SER A . n 
A 1 956  SER 956  956  956  SER SER A . n 
A 1 957  THR 957  957  957  THR THR A . n 
A 1 958  LYS 958  958  958  LYS LYS A . n 
A 1 959  SER 959  959  959  SER SER A . n 
A 1 960  GLN 960  960  960  GLN GLN A . n 
A 1 961  SER 961  961  961  SER SER A . n 
A 1 962  GLN 962  962  962  GLN GLN A . n 
A 1 963  ASN 963  963  963  ASN ASN A . n 
A 1 964  SER 964  964  964  SER SER A . n 
A 1 965  ARG 965  965  965  ARG ARG A . n 
A 1 966  GLN 966  966  966  GLN GLN A . n 
A 1 967  ARG 967  967  967  ARG ARG A . n 
A 1 968  LEU 968  968  968  LEU LEU A . n 
A 1 969  ILE 969  969  969  ILE ILE A . n 
A 1 970  ASP 970  970  970  ASP ASP A . n 
A 1 971  ASP 971  971  971  ASP ASP A . n 
A 1 972  PHE 972  972  972  PHE PHE A . n 
A 1 973  GLN 973  973  973  GLN GLN A . n 
A 1 974  ALA 974  974  974  ALA ALA A . n 
A 1 975  GLN 975  975  975  GLN GLN A . n 
A 1 976  PRO 976  976  976  PRO PRO A . n 
A 1 977  GLY 977  977  977  GLY GLY A . n 
A 1 978  PHE 978  978  978  PHE PHE A . n 
A 1 979  GLY 979  979  979  GLY GLY A . n 
A 1 980  VAL 980  980  980  VAL VAL A . n 
A 1 981  ILE 981  981  981  ILE ILE A . n 
A 1 982  ILE 982  982  982  ILE ILE A . n 
A 1 983  LEU 983  983  983  LEU LEU A . n 
A 1 984  SER 984  984  984  SER SER A . n 
A 1 985  THR 985  985  985  THR THR A . n 
A 1 986  VAL 986  986  986  VAL VAL A . n 
A 1 987  ALA 987  987  987  ALA ALA A . n 
A 1 988  VAL 988  988  988  VAL VAL A . n 
A 1 989  GLY 989  989  989  GLY GLY A . n 
A 1 990  PHE 990  990  990  PHE PHE A . n 
A 1 991  GLY 991  991  991  GLY GLY A . n 
A 1 992  VAL 992  992  992  VAL VAL A . n 
A 1 993  ASN 993  993  993  ASN ASN A . n 
A 1 994  VAL 994  994  994  VAL VAL A . n 
A 1 995  GLN 995  995  995  GLN GLN A . n 
A 1 996  LYS 996  996  996  LYS LYS A . n 
A 1 997  ALA 997  997  997  ALA ALA A . n 
A 1 998  ASN 998  998  998  ASN ASN A . n 
A 1 999  HIS 999  999  999  HIS HIS A . n 
A 1 1000 VAL 1000 1000 1000 VAL VAL A . n 
A 1 1001 ILE 1001 1001 1001 ILE ILE A . n 
A 1 1002 HIS 1002 1002 1002 HIS HIS A . n 
A 1 1003 PHE 1003 1003 1003 PHE PHE A . n 
A 1 1004 THR 1004 1004 1004 THR THR A . n 
A 1 1005 ARG 1005 1005 1005 ARG ARG A . n 
A 1 1006 CYS 1006 1006 1006 CYS CYS A . n 
A 1 1007 TRP 1007 1007 1007 TRP TRP A . n 
A 1 1008 ASN 1008 1008 1008 ASN ASN A . n 
A 1 1009 PRO 1009 1009 1009 PRO PRO A . n 
A 1 1010 ALA 1010 1010 1010 ALA ALA A . n 
A 1 1011 LYS 1011 1011 1011 LYS LYS A . n 
A 1 1012 GLU 1012 1012 1012 GLU GLU A . n 
A 1 1013 ASP 1013 1013 1013 ASP ASP A . n 
A 1 1014 GLN 1014 1014 1014 GLN GLN A . n 
A 1 1015 ALA 1015 1015 1015 ALA ALA A . n 
A 1 1016 THR 1016 1016 1016 THR THR A . n 
A 1 1017 ASP 1017 1017 1017 ASP ASP A . n 
A 1 1018 ARG 1018 1018 1018 ARG ARG A . n 
A 1 1019 ALA 1019 1019 1019 ALA ALA A . n 
A 1 1020 TYR 1020 1020 1020 TYR TYR A . n 
A 1 1021 ARG 1021 1021 1021 ARG ARG A . n 
A 1 1022 ILE 1022 1022 1022 ILE ILE A . n 
A 1 1023 GLY 1023 1023 1023 GLY GLY A . n 
A 1 1024 GLN 1024 1024 1024 GLN GLN A . n 
A 1 1025 THR 1025 1025 1025 THR THR A . n 
A 1 1026 LYS 1026 1026 1026 LYS LYS A . n 
A 1 1027 ASN 1027 1027 1027 ASN ASN A . n 
A 1 1028 VAL 1028 1028 1028 VAL VAL A . n 
A 1 1029 TYR 1029 1029 1029 TYR TYR A . n 
A 1 1030 VAL 1030 1030 1030 VAL VAL A . n 
A 1 1031 TYR 1031 1031 1031 TYR TYR A . n 
A 1 1032 TYR 1032 1032 1032 TYR TYR A . n 
A 1 1033 PRO 1033 1033 1033 PRO PRO A . n 
A 1 1034 THR 1034 1034 1034 THR THR A . n 
A 1 1035 VAL 1035 1035 1035 VAL VAL A . n 
A 1 1036 ARG 1036 1036 1036 ARG ARG A . n 
A 1 1037 ASP 1037 1037 1037 ASP ASP A . n 
A 1 1038 THR 1038 1038 1038 THR THR A . n 
A 1 1039 GLU 1039 1039 1039 GLU GLU A . n 
A 1 1040 ILE 1040 1040 1040 ILE ILE A . n 
A 1 1041 THR 1041 1041 1041 THR THR A . n 
A 1 1042 THR 1042 1042 1042 THR THR A . n 
A 1 1043 PHE 1043 1043 1043 PHE PHE A . n 
A 1 1044 GLU 1044 1044 1044 GLU GLU A . n 
A 1 1045 GLU 1045 1045 1045 GLU GLU A . n 
A 1 1046 THR 1046 1046 1046 THR THR A . n 
A 1 1047 LEU 1047 1047 1047 LEU LEU A . n 
A 1 1048 ASP 1048 1048 1048 ASP ASP A . n 
A 1 1049 ASP 1049 1049 1049 ASP ASP A . n 
A 1 1050 LEU 1050 1050 1050 LEU LEU A . n 
A 1 1051 LEU 1051 1051 1051 LEU LEU A . n 
A 1 1052 GLN 1052 1052 1052 GLN GLN A . n 
A 1 1053 ARG 1053 1053 1053 ARG ARG A . n 
A 1 1054 ARG 1054 1054 1054 ARG ARG A . n 
A 1 1055 ARG 1055 1055 1055 ARG ARG A . n 
A 1 1056 ALA 1056 1056 1056 ALA ALA A . n 
A 1 1057 LEU 1057 1057 1057 LEU LEU A . n 
A 1 1058 ALA 1058 1058 1058 ALA ALA A . n 
A 1 1059 ARG 1059 1059 1059 ARG ARG A . n 
A 1 1060 ASP 1060 1060 1060 ASP ASP A . n 
A 1 1061 MET 1061 1061 1061 MET MET A . n 
A 1 1062 LEU 1062 1062 1062 LEU LEU A . n 
A 1 1063 CYS 1063 1063 1063 CYS CYS A . n 
A 1 1064 ALA 1064 1064 1064 ALA ALA A . n 
A 1 1065 THR 1065 1065 1065 THR THR A . n 
A 1 1066 PRO 1066 1066 1066 PRO PRO A . n 
A 1 1067 ASP 1067 1067 1067 ASP ASP A . n 
A 1 1068 LEU 1068 1068 1068 LEU LEU A . n 
A 1 1069 ASN 1069 1069 1069 ASN ASN A . n 
A 1 1070 CYS 1070 1070 1070 CYS CYS A . n 
A 1 1071 ALA 1071 1071 1071 ALA ALA A . n 
A 1 1072 ASP 1072 1072 1072 ASP ASP A . n 
A 1 1073 PHE 1073 1073 1073 PHE PHE A . n 
A 1 1074 GLU 1074 1074 1074 GLU GLU A . n 
A 1 1075 THR 1075 1075 1075 THR THR A . n 
A 1 1076 ILE 1076 1076 1076 ILE ILE A . n 
A 1 1077 LEU 1077 1077 1077 LEU LEU A . n 
A 1 1078 LYS 1078 1078 1078 LYS LYS A . n 
A 1 1079 GLY 1079 1079 1079 GLY GLY A . n 
A 1 1080 ALA 1080 1080 ?    ?   ?   A . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A TYR 851 ? CB  ? A TYR 851 CB  
2 1 Y 1 A TYR 851 ? CG  ? A TYR 851 CG  
3 1 Y 1 A TYR 851 ? CD1 ? A TYR 851 CD1 
4 1 Y 1 A TYR 851 ? CD2 ? A TYR 851 CD2 
5 1 Y 1 A TYR 851 ? CE1 ? A TYR 851 CE1 
6 1 Y 1 A TYR 851 ? CE2 ? A TYR 851 CE2 
7 1 Y 1 A TYR 851 ? CZ  ? A TYR 851 CZ  
8 1 Y 1 A TYR 851 ? OH  ? A TYR 851 OH  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8QY7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8QY7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8QY7 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8QY7 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.018 ? 7335 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.700 ? 9974 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.748 ? 955  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.045 ? 1117 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.010 ? 1294 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8QY7 
_struct.title                        'Zorya anti-bacteriophage defense system ZorD apo form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8QY7 
_struct_keywords.text            'Nuclease, ANTIVIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIVIRAL PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0V7WZM1_ECOLX 
_struct_ref.pdbx_db_accession          A0A0V7WZM1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MLKRLLSKLTGNRQQIEHHLKNQYQVEENGLSFPLSLVDDSQLWALASWLEQLAEEDYLISLTDRWLLSWEALYRLLEDE
EHASSLPLIGVPDILPLRASLSSRGALSDSDFRVWIAEWATFPARKPIRFSRTGAILTHDNQQYLLSRENWALLQATEQL
SAQQIQTPGETTNQLGWAAIRKCAKLAAAKFDDYLEKTHVIKPTSLSLRLRKATVADTAVIEIEPHFEDQPANWLGSFDK
NLQVHDSYRIPGENGELSHVIIPPEVKEVLNSIHSIPGRRVAGSEALSFVRNPYTFLGEDAASVIAPEEHEQALFDARIF
FHHFRLIPQLNTENKITEVTLILEPVSPVPQPEITFVFSAPWELDKFIQQLGISVAAQMPAGSWQGYELELSQFTEQQWH
DCQALLTRWQQEIEGKEFSDVLDIAKYGDRVIGIGEFEKISSPWLTKAQSENWLPDGIDFSAFSIETLSGWQPENPLHFD
ELQEIITQAEAAGETYITTPWNDSQLPLDAAKTFSKNWEKQQITANEYQGNVADKTARAVLKIEQNIEETAYIKQRRNSL
LNARHAEPEIPLSLKEHIRLKDHQREGVAWLQQLFLRSPEETAGCLLADDMGLGKTLQILSFLVWFIEKFPQEPPNLIVA
PVSLLDNWERELNNFFYTAGIPVLKLYGETIKAVKYPKQAIPAHLQSKGIKNLLKPGWQGEAKIILTTYETLRDQEFSLA
RQPWSIMVCDEAQKIKNPAALITHAANAVQARFKVACTGTPVENTLVDLWSLFDFAQPGLLGALNEFGKQYVRPIENEDG
RDTERLESLRALIEPQTLRRTKEEVARDLPQKIEVESCKQLTLSGVQKQLYLSSVANWQQQQALREGMQQAGTGMLGLLH
RLKLICAHPAIVNPEPRFRDNSPKLNWLLKILAEIKHTSKDKVIIFTELRDLQRELQHAIHQNFGFRPVIINGDSSTKSQ
SQNSRQRLIDDFQAQPGFGVIILSTVAVGFGVNVQKANHVIHFTRCWNPAKEDQATDRAYRIGQTKNVYVYYPTVRDTEI
TTFEETLDDLLQRRRALARDMLCATPDLNCADFETILKGA
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8QY7 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1080 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A0V7WZM1 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1080 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       1080 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 36   ? VAL A 38   ? SER A 36   VAL A 38   5 ? 3  
HELX_P HELX_P2  AA2 LEU A 43   ? GLU A 56   ? LEU A 43   GLU A 56   1 ? 14 
HELX_P HELX_P3  AA3 TRP A 70   ? ASP A 79   ? TRP A 70   ASP A 79   1 ? 10 
HELX_P HELX_P4  AA4 SER A 85   ? ILE A 89   ? SER A 85   ILE A 89   5 ? 5  
HELX_P HELX_P5  AA5 SER A 147  ? ILE A 165  ? SER A 147  ILE A 165  1 ? 19 
HELX_P HELX_P6  AA6 GLY A 169  ? ALA A 188  ? GLY A 169  ALA A 188  1 ? 20 
HELX_P HELX_P7  AA7 ASP A 192  ? LYS A 197  ? ASP A 192  LYS A 197  1 ? 6  
HELX_P HELX_P8  AA8 ASN A 233  ? ASN A 241  ? ASN A 233  ASN A 241  1 ? 9  
HELX_P HELX_P9  AA9 PRO A 263  ? ILE A 276  ? PRO A 263  ILE A 276  1 ? 14 
HELX_P HELX_P10 AB1 GLY A 283  ? ASN A 292  ? GLY A 283  ASN A 292  1 ? 10 
HELX_P HELX_P11 AB2 ASN A 292  ? GLY A 298  ? ASN A 292  GLY A 298  1 ? 7  
HELX_P HELX_P12 AB3 ASP A 300  ? ILE A 305  ? ASP A 300  ILE A 305  1 ? 6  
HELX_P HELX_P13 AB4 ALA A 306  ? ALA A 317  ? ALA A 306  ALA A 317  1 ? 12 
HELX_P HELX_P14 AB5 ALA A 360  ? ALA A 377  ? ALA A 360  ALA A 377  1 ? 18 
HELX_P HELX_P15 AB6 THR A 395  ? GLU A 414  ? THR A 395  GLU A 414  1 ? 20 
HELX_P HELX_P16 AB7 LYS A 581  ? LEU A 596  ? LYS A 581  LEU A 596  1 ? 16 
HELX_P HELX_P17 AB8 GLY A 614  ? PHE A 630  ? GLY A 614  PHE A 630  1 ? 17 
HELX_P HELX_P18 AB9 PRO A 641  ? PHE A 656  ? PRO A 641  PHE A 656  1 ? 16 
HELX_P HELX_P19 AC1 TYR A 657  ? ILE A 661  ? TYR A 657  ILE A 661  5 ? 5  
HELX_P HELX_P20 AC2 GLY A 668  ? VAL A 674  ? GLY A 668  VAL A 674  1 ? 7  
HELX_P HELX_P21 AC3 PRO A 682  ? LYS A 688  ? PRO A 682  LYS A 688  1 ? 7  
HELX_P HELX_P22 AC4 THR A 708  ? GLN A 715  ? THR A 708  GLN A 715  1 ? 8  
HELX_P HELX_P23 AC5 GLN A 715  ? GLN A 722  ? GLN A 715  GLN A 722  1 ? 8  
HELX_P HELX_P24 AC6 ALA A 732  ? LYS A 736  ? ALA A 732  LYS A 736  5 ? 5  
HELX_P HELX_P25 AC7 ALA A 740  ? VAL A 749  ? ALA A 740  VAL A 749  1 ? 10 
HELX_P HELX_P26 AC8 THR A 765  ? GLN A 777  ? THR A 765  GLN A 777  1 ? 13 
HELX_P HELX_P27 AC9 ALA A 783  ? VAL A 792  ? ALA A 783  VAL A 792  1 ? 10 
HELX_P HELX_P28 AD1 GLU A 804  ? GLU A 814  ? GLU A 804  GLU A 814  1 ? 11 
HELX_P HELX_P29 AD2 GLU A 836  ? GLN A 840  ? GLU A 836  GLN A 840  5 ? 5  
HELX_P HELX_P30 AD3 SER A 844  ? LEU A 864  ? SER A 844  LEU A 864  1 ? 21 
HELX_P HELX_P31 AD4 MET A 875  ? HIS A 888  ? MET A 875  HIS A 888  1 ? 14 
HELX_P HELX_P32 AD5 HIS A 888  ? ASN A 893  ? HIS A 888  ASN A 893  1 ? 6  
HELX_P HELX_P33 AD6 GLU A 895  ? ASP A 900  ? GLU A 895  ASP A 900  1 ? 6  
HELX_P HELX_P34 AD7 SER A 902  ? SER A 919  ? SER A 902  SER A 919  1 ? 18 
HELX_P HELX_P35 AD8 LEU A 929  ? GLY A 945  ? LEU A 929  GLY A 945  1 ? 17 
HELX_P HELX_P36 AD9 SER A 959  ? GLN A 975  ? SER A 959  GLN A 975  1 ? 17 
HELX_P HELX_P37 AE1 ASN A 1008 ? ASP A 1017 ? ASN A 1008 ASP A 1017 1 ? 10 
HELX_P HELX_P38 AE2 THR A 1042 ? ARG A 1059 ? THR A 1042 ARG A 1059 1 ? 18 
HELX_P HELX_P39 AE3 ASN A 1069 ? PHE A 1073 ? ASN A 1069 PHE A 1073 5 ? 5  
HELX_P HELX_P40 AE4 GLU A 1074 ? GLY A 1079 ? GLU A 1074 GLY A 1079 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 3 ? 
AA6 ? 5 ? 
AA7 ? 7 ? 
AA8 ? 6 ? 
AA9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? parallel      
AA6 4 5 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA9 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 25   ? VAL A 26   ? GLN A 25   VAL A 26   
AA1 2 GLY A 30   ? PRO A 34   ? GLY A 30   PRO A 34   
AA1 3 ARG A 65   ? SER A 69   ? ARG A 65   SER A 69   
AA1 4 ILE A 60   ? SER A 61   ? ILE A 60   SER A 61   
AA2 1 LEU A 97   ? ARG A 104  ? LEU A 97   ARG A 104  
AA2 2 ARG A 113  ? THR A 121  ? ARG A 113  THR A 121  
AA3 1 SER A 131  ? THR A 133  ? SER A 131  THR A 133  
AA3 2 ILE A 136  ? THR A 138  ? ILE A 136  THR A 138  
AA4 1 THR A 198  ? ILE A 201  ? THR A 198  ILE A 201  
AA4 2 LEU A 257  ? ILE A 261  ? LEU A 257  ILE A 261  
AA4 3 SER A 247  ? PRO A 251  ? SER A 247  PRO A 251  
AA5 1 SER A 207  ? THR A 214  ? SER A 207  THR A 214  
AA5 2 ALA A 219  ? HIS A 226  ? ALA A 219  HIS A 226  
AA5 3 ARG A 280  ? VAL A 281  ? ARG A 280  VAL A 281  
AA6 1 ILE A 354  ? PHE A 358  ? ILE A 354  PHE A 358  
AA6 2 VAL A 339  ? GLU A 344  ? VAL A 339  GLU A 344  
AA6 3 PHE A 321  ? PRO A 328  ? PHE A 321  PRO A 328  
AA6 4 TYR A 387  ? GLU A 390  ? TYR A 387  GLU A 390  
AA6 5 ALA A 381  ? TRP A 384  ? ALA A 381  TRP A 384  
AA7 1 VAL A 663  ? LEU A 666  ? VAL A 663  LEU A 666  
AA7 2 ILE A 704  ? THR A 707  ? ILE A 704  THR A 707  
AA7 3 ASN A 636  ? VAL A 639  ? ASN A 636  VAL A 639  
AA7 4 TRP A 724  ? ASP A 730  ? TRP A 724  ASP A 730  
AA7 5 ALA A 751  ? CYS A 757  ? ALA A 751  CYS A 757  
AA7 6 GLY A 604  ? LEU A 607  ? GLY A 604  LEU A 607  
AA7 7 THR A 817  ? LEU A 818  ? THR A 817  LEU A 818  
AA8 1 LYS A 832  ? GLU A 834  ? LYS A 832  GLU A 834  
AA8 2 VAL A 1028 ? TYR A 1031 ? VAL A 1028 TYR A 1031 
AA8 3 ALA A 997  ? HIS A 1002 ? ALA A 997  HIS A 1002 
AA8 4 LYS A 922  ? PHE A 926  ? LYS A 922  PHE A 926  
AA8 5 GLY A 979  ? LEU A 983  ? GLY A 979  LEU A 983  
AA8 6 VAL A 949  ? ILE A 951  ? VAL A 949  ILE A 951  
AA9 1 LEU A 841  ? THR A 842  ? LEU A 841  THR A 842  
AA9 2 VAL A 1035 ? ARG A 1036 ? VAL A 1035 ARG A 1036 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 25   ? N GLN A 25   O SER A 32   ? O SER A 32   
AA1 2 3 N PHE A 33   ? N PHE A 33   O TRP A 66   ? O TRP A 66   
AA1 3 4 O LEU A 67   ? O LEU A 67   N ILE A 60   ? N ILE A 60   
AA2 1 2 N SER A 102  ? N SER A 102  O TRP A 115  ? O TRP A 115  
AA3 1 2 N THR A 133  ? N THR A 133  O ILE A 136  ? O ILE A 136  
AA4 1 2 N ILE A 201  ? N ILE A 201  O ILE A 261  ? O ILE A 261  
AA4 2 3 O VAL A 260  ? O VAL A 260  N TYR A 248  ? N TYR A 248  
AA5 1 2 N ALA A 213  ? N ALA A 213  O VAL A 220  ? O VAL A 220  
AA5 2 3 N ILE A 221  ? N ILE A 221  O VAL A 281  ? O VAL A 281  
AA6 1 2 O PHE A 358  ? O PHE A 358  N VAL A 339  ? N VAL A 339  
AA6 2 3 O GLU A 344  ? O GLU A 344  N HIS A 323  ? N HIS A 323  
AA6 3 4 N HIS A 322  ? N HIS A 322  O GLU A 388  ? O GLU A 388  
AA6 4 5 O LEU A 389  ? O LEU A 389  N GLY A 382  ? N GLY A 382  
AA7 1 2 N LEU A 664  ? N LEU A 664  O LEU A 706  ? O LEU A 706  
AA7 2 3 O ILE A 705  ? O ILE A 705  N ASN A 636  ? N ASN A 636  
AA7 3 4 N LEU A 637  ? N LEU A 637  O VAL A 728  ? O VAL A 728  
AA7 4 5 N CYS A 729  ? N CYS A 729  O VAL A 755  ? O VAL A 755  
AA7 5 6 O ALA A 756  ? O ALA A 756  N LEU A 607  ? N LEU A 607  
AA7 6 7 N LEU A 606  ? N LEU A 606  O LEU A 818  ? O LEU A 818  
AA8 1 2 N ILE A 833  ? N ILE A 833  O VAL A 1030 ? O VAL A 1030 
AA8 2 3 O TYR A 1031 ? O TYR A 1031 N VAL A 1000 ? N VAL A 1000 
AA8 3 4 O ILE A 1001 ? O ILE A 1001 N PHE A 926  ? N PHE A 926  
AA8 4 5 N VAL A 923  ? N VAL A 923  O GLY A 979  ? O GLY A 979  
AA8 5 6 O ILE A 982  ? O ILE A 982  N VAL A 949  ? N VAL A 949  
AA9 1 2 N LEU A 841  ? N LEU A 841  O ARG A 1036 ? O ARG A 1036 
# 
_pdbx_entry_details.entry_id                   8QY7 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O A TYR 74  ? ? OE1 A GLU 78  ? ? 1.79 
2 1 O A GLN 410 ? ? OE1 A GLU 414 ? ? 2.05 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CD A GLU 78  ? ? OE1 A GLU 78  ? ? 1.103 1.252 -0.149 0.011 N 
2 1 CB A PRO 723 ? ? CG  A PRO 723 ? ? 1.020 1.495 -0.475 0.050 N 
3 1 CG A PRO 723 ? ? CD  A PRO 723 ? ? 1.115 1.502 -0.387 0.033 N 
4 1 CA A PRO 794 ? ? CB  A PRO 794 ? ? 1.661 1.531 0.130  0.020 N 
5 1 CB A PRO 794 ? ? CG  A PRO 794 ? ? 2.086 1.495 0.591  0.050 N 
6 1 CG A PRO 794 ? ? CD  A PRO 794 ? ? 1.248 1.502 -0.254 0.033 N 
7 1 CB A PRO 830 ? ? CG  A PRO 830 ? ? 2.498 1.495 1.003  0.050 N 
8 1 CG A PRO 830 ? ? CD  A PRO 830 ? ? 1.007 1.502 -0.495 0.033 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 C  A SER 347 ? ? N   A PRO 348 ? ? CD  A PRO 348 ? ? 141.89 128.40 13.49  2.10 Y 
2  1 CA A PRO 348 ? ? N   A PRO 348 ? ? CD  A PRO 348 ? ? 99.77  111.70 -11.93 1.40 N 
3  1 N  A PRO 348 ? ? CD  A PRO 348 ? ? CG  A PRO 348 ? ? 91.04  103.20 -12.16 1.50 N 
4  1 C  A GLN 722 ? ? N   A PRO 723 ? ? CD  A PRO 723 ? ? 146.51 128.40 18.11  2.10 Y 
5  1 CA A PRO 723 ? ? N   A PRO 723 ? ? CD  A PRO 723 ? ? 95.56  111.70 -16.14 1.40 N 
6  1 CA A PRO 723 ? ? CB  A PRO 723 ? ? CG  A PRO 723 ? ? 70.40  104.80 -34.40 1.90 N 
7  1 CB A PRO 723 ? ? CG  A PRO 723 ? ? CD  A PRO 723 ? ? 179.95 106.50 73.45  3.90 N 
8  1 N  A PRO 723 ? ? CD  A PRO 723 ? ? CG  A PRO 723 ? ? 79.60  103.20 -23.60 1.50 N 
9  1 CZ A PHE 773 ? ? CE2 A PHE 773 ? ? CD2 A PHE 773 ? ? 128.66 120.10 8.56   1.20 N 
10 1 C  A ARG 793 ? ? N   A PRO 794 ? ? CD  A PRO 794 ? ? 144.05 128.40 15.65  2.10 Y 
11 1 CA A PRO 794 ? ? N   A PRO 794 ? ? CD  A PRO 794 ? ? 78.00  111.70 -33.70 1.40 N 
12 1 CB A PRO 794 ? ? CG  A PRO 794 ? ? CD  A PRO 794 ? ? 39.67  106.50 -66.83 3.90 N 
13 1 N  A PRO 794 ? ? CD  A PRO 794 ? ? CG  A PRO 794 ? ? 123.09 103.20 19.89  1.50 N 
14 1 C  A LEU 829 ? ? N   A PRO 830 ? ? CD  A PRO 830 ? ? 147.38 128.40 18.98  2.10 Y 
15 1 CA A PRO 830 ? ? N   A PRO 830 ? ? CD  A PRO 830 ? ? 88.58  111.70 -23.12 1.40 N 
16 1 N  A PRO 830 ? ? CA  A PRO 830 ? ? CB  A PRO 830 ? ? 92.79  103.30 -10.51 1.20 N 
17 1 CA A PRO 830 ? ? CB  A PRO 830 ? ? CG  A PRO 830 ? ? 89.33  104.80 -15.47 1.90 N 
18 1 CB A PRO 830 ? ? CG  A PRO 830 ? ? CD  A PRO 830 ? ? 19.13  106.50 -87.37 3.90 N 
19 1 N  A PRO 830 ? ? CD  A PRO 830 ? ? CG  A PRO 830 ? ? 117.32 103.20 14.12  1.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 THR A 63   ? ? 76.23   -8.72   
2 1 PRO A 87   ? ? -56.29  -8.61   
3 1 GLU A 118  ? ? -176.11 130.63  
4 1 SER A 956  ? ? 50.65   -134.98 
5 1 HIS A 999  ? ? -164.66 110.60  
6 1 ASP A 1017 ? ? -81.48  49.54   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ILE 
_pdbx_validate_peptide_omega.auth_asym_id_1   A 
_pdbx_validate_peptide_omega.auth_seq_id_1    336 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   THR 
_pdbx_validate_peptide_omega.auth_asym_id_2   A 
_pdbx_validate_peptide_omega.auth_seq_id_2    337 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            149.20 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8QY7 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8QY7 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.66 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               332426 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'Zorya anti-bacteriophage defense system ZorD apo form' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8QY7 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8QY7 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8QY7 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1    
2   1 Y 1 A LEU 2    ? A LEU 2    
3   1 Y 1 A LYS 3    ? A LYS 3    
4   1 Y 1 A ARG 4    ? A ARG 4    
5   1 Y 1 A LEU 5    ? A LEU 5    
6   1 Y 1 A LEU 6    ? A LEU 6    
7   1 Y 1 A SER 7    ? A SER 7    
8   1 Y 1 A LYS 8    ? A LYS 8    
9   1 Y 1 A LEU 9    ? A LEU 9    
10  1 Y 1 A THR 10   ? A THR 10   
11  1 Y 1 A GLY 11   ? A GLY 11   
12  1 Y 1 A ASN 12   ? A ASN 12   
13  1 Y 1 A ARG 13   ? A ARG 13   
14  1 Y 1 A GLN 14   ? A GLN 14   
15  1 Y 1 A GLN 15   ? A GLN 15   
16  1 Y 1 A ILE 16   ? A ILE 16   
17  1 Y 1 A GLU 17   ? A GLU 17   
18  1 Y 1 A HIS 18   ? A HIS 18   
19  1 Y 1 A HIS 19   ? A HIS 19   
20  1 Y 1 A LEU 20   ? A LEU 20   
21  1 Y 1 A GLY 415  ? A GLY 415  
22  1 Y 1 A LYS 416  ? A LYS 416  
23  1 Y 1 A GLU 417  ? A GLU 417  
24  1 Y 1 A PHE 418  ? A PHE 418  
25  1 Y 1 A SER 419  ? A SER 419  
26  1 Y 1 A ASP 420  ? A ASP 420  
27  1 Y 1 A VAL 421  ? A VAL 421  
28  1 Y 1 A LEU 422  ? A LEU 422  
29  1 Y 1 A ASP 423  ? A ASP 423  
30  1 Y 1 A ILE 424  ? A ILE 424  
31  1 Y 1 A ALA 425  ? A ALA 425  
32  1 Y 1 A LYS 426  ? A LYS 426  
33  1 Y 1 A TYR 427  ? A TYR 427  
34  1 Y 1 A GLY 428  ? A GLY 428  
35  1 Y 1 A ASP 429  ? A ASP 429  
36  1 Y 1 A ARG 430  ? A ARG 430  
37  1 Y 1 A VAL 431  ? A VAL 431  
38  1 Y 1 A ILE 432  ? A ILE 432  
39  1 Y 1 A GLY 433  ? A GLY 433  
40  1 Y 1 A ILE 434  ? A ILE 434  
41  1 Y 1 A GLY 435  ? A GLY 435  
42  1 Y 1 A GLU 436  ? A GLU 436  
43  1 Y 1 A PHE 437  ? A PHE 437  
44  1 Y 1 A GLU 438  ? A GLU 438  
45  1 Y 1 A LYS 439  ? A LYS 439  
46  1 Y 1 A ILE 440  ? A ILE 440  
47  1 Y 1 A SER 441  ? A SER 441  
48  1 Y 1 A SER 442  ? A SER 442  
49  1 Y 1 A PRO 443  ? A PRO 443  
50  1 Y 1 A TRP 444  ? A TRP 444  
51  1 Y 1 A LEU 445  ? A LEU 445  
52  1 Y 1 A THR 446  ? A THR 446  
53  1 Y 1 A LYS 447  ? A LYS 447  
54  1 Y 1 A ALA 448  ? A ALA 448  
55  1 Y 1 A GLN 449  ? A GLN 449  
56  1 Y 1 A SER 450  ? A SER 450  
57  1 Y 1 A GLU 451  ? A GLU 451  
58  1 Y 1 A ASN 452  ? A ASN 452  
59  1 Y 1 A TRP 453  ? A TRP 453  
60  1 Y 1 A LEU 454  ? A LEU 454  
61  1 Y 1 A PRO 455  ? A PRO 455  
62  1 Y 1 A ASP 456  ? A ASP 456  
63  1 Y 1 A GLY 457  ? A GLY 457  
64  1 Y 1 A ILE 458  ? A ILE 458  
65  1 Y 1 A ASP 459  ? A ASP 459  
66  1 Y 1 A PHE 460  ? A PHE 460  
67  1 Y 1 A SER 461  ? A SER 461  
68  1 Y 1 A ALA 462  ? A ALA 462  
69  1 Y 1 A PHE 463  ? A PHE 463  
70  1 Y 1 A SER 464  ? A SER 464  
71  1 Y 1 A ILE 465  ? A ILE 465  
72  1 Y 1 A GLU 466  ? A GLU 466  
73  1 Y 1 A THR 467  ? A THR 467  
74  1 Y 1 A LEU 468  ? A LEU 468  
75  1 Y 1 A SER 469  ? A SER 469  
76  1 Y 1 A GLY 470  ? A GLY 470  
77  1 Y 1 A TRP 471  ? A TRP 471  
78  1 Y 1 A GLN 472  ? A GLN 472  
79  1 Y 1 A PRO 473  ? A PRO 473  
80  1 Y 1 A GLU 474  ? A GLU 474  
81  1 Y 1 A ASN 475  ? A ASN 475  
82  1 Y 1 A PRO 476  ? A PRO 476  
83  1 Y 1 A LEU 477  ? A LEU 477  
84  1 Y 1 A HIS 478  ? A HIS 478  
85  1 Y 1 A PHE 479  ? A PHE 479  
86  1 Y 1 A ASP 480  ? A ASP 480  
87  1 Y 1 A GLU 481  ? A GLU 481  
88  1 Y 1 A LEU 482  ? A LEU 482  
89  1 Y 1 A GLN 483  ? A GLN 483  
90  1 Y 1 A GLU 484  ? A GLU 484  
91  1 Y 1 A ILE 485  ? A ILE 485  
92  1 Y 1 A ILE 486  ? A ILE 486  
93  1 Y 1 A THR 487  ? A THR 487  
94  1 Y 1 A GLN 488  ? A GLN 488  
95  1 Y 1 A ALA 489  ? A ALA 489  
96  1 Y 1 A GLU 490  ? A GLU 490  
97  1 Y 1 A ALA 491  ? A ALA 491  
98  1 Y 1 A ALA 492  ? A ALA 492  
99  1 Y 1 A GLY 493  ? A GLY 493  
100 1 Y 1 A GLU 494  ? A GLU 494  
101 1 Y 1 A THR 495  ? A THR 495  
102 1 Y 1 A TYR 496  ? A TYR 496  
103 1 Y 1 A ILE 497  ? A ILE 497  
104 1 Y 1 A THR 498  ? A THR 498  
105 1 Y 1 A THR 499  ? A THR 499  
106 1 Y 1 A PRO 500  ? A PRO 500  
107 1 Y 1 A TRP 501  ? A TRP 501  
108 1 Y 1 A ASN 502  ? A ASN 502  
109 1 Y 1 A ASP 503  ? A ASP 503  
110 1 Y 1 A SER 504  ? A SER 504  
111 1 Y 1 A GLN 505  ? A GLN 505  
112 1 Y 1 A LEU 506  ? A LEU 506  
113 1 Y 1 A PRO 507  ? A PRO 507  
114 1 Y 1 A LEU 508  ? A LEU 508  
115 1 Y 1 A ASP 509  ? A ASP 509  
116 1 Y 1 A ALA 510  ? A ALA 510  
117 1 Y 1 A ALA 511  ? A ALA 511  
118 1 Y 1 A LYS 512  ? A LYS 512  
119 1 Y 1 A THR 513  ? A THR 513  
120 1 Y 1 A PHE 514  ? A PHE 514  
121 1 Y 1 A SER 515  ? A SER 515  
122 1 Y 1 A LYS 516  ? A LYS 516  
123 1 Y 1 A ASN 517  ? A ASN 517  
124 1 Y 1 A TRP 518  ? A TRP 518  
125 1 Y 1 A GLU 519  ? A GLU 519  
126 1 Y 1 A LYS 520  ? A LYS 520  
127 1 Y 1 A GLN 521  ? A GLN 521  
128 1 Y 1 A GLN 522  ? A GLN 522  
129 1 Y 1 A ILE 523  ? A ILE 523  
130 1 Y 1 A THR 524  ? A THR 524  
131 1 Y 1 A ALA 525  ? A ALA 525  
132 1 Y 1 A ASN 526  ? A ASN 526  
133 1 Y 1 A GLU 527  ? A GLU 527  
134 1 Y 1 A TYR 528  ? A TYR 528  
135 1 Y 1 A GLN 529  ? A GLN 529  
136 1 Y 1 A GLY 530  ? A GLY 530  
137 1 Y 1 A ASN 531  ? A ASN 531  
138 1 Y 1 A VAL 532  ? A VAL 532  
139 1 Y 1 A ALA 533  ? A ALA 533  
140 1 Y 1 A ASP 534  ? A ASP 534  
141 1 Y 1 A LYS 535  ? A LYS 535  
142 1 Y 1 A THR 536  ? A THR 536  
143 1 Y 1 A ALA 537  ? A ALA 537  
144 1 Y 1 A ARG 538  ? A ARG 538  
145 1 Y 1 A ALA 539  ? A ALA 539  
146 1 Y 1 A VAL 540  ? A VAL 540  
147 1 Y 1 A LEU 541  ? A LEU 541  
148 1 Y 1 A LYS 542  ? A LYS 542  
149 1 Y 1 A ILE 543  ? A ILE 543  
150 1 Y 1 A GLU 544  ? A GLU 544  
151 1 Y 1 A GLN 545  ? A GLN 545  
152 1 Y 1 A ASN 546  ? A ASN 546  
153 1 Y 1 A ILE 547  ? A ILE 547  
154 1 Y 1 A GLU 548  ? A GLU 548  
155 1 Y 1 A GLU 549  ? A GLU 549  
156 1 Y 1 A THR 550  ? A THR 550  
157 1 Y 1 A ALA 551  ? A ALA 551  
158 1 Y 1 A TYR 552  ? A TYR 552  
159 1 Y 1 A ILE 553  ? A ILE 553  
160 1 Y 1 A LYS 554  ? A LYS 554  
161 1 Y 1 A GLN 555  ? A GLN 555  
162 1 Y 1 A ARG 556  ? A ARG 556  
163 1 Y 1 A ARG 557  ? A ARG 557  
164 1 Y 1 A ASN 558  ? A ASN 558  
165 1 Y 1 A SER 559  ? A SER 559  
166 1 Y 1 A LEU 560  ? A LEU 560  
167 1 Y 1 A LEU 561  ? A LEU 561  
168 1 Y 1 A ASN 562  ? A ASN 562  
169 1 Y 1 A ALA 563  ? A ALA 563  
170 1 Y 1 A ARG 564  ? A ARG 564  
171 1 Y 1 A HIS 565  ? A HIS 565  
172 1 Y 1 A ASN 797  ? A ASN 797  
173 1 Y 1 A GLU 798  ? A GLU 798  
174 1 Y 1 A ASP 799  ? A ASP 799  
175 1 Y 1 A GLY 800  ? A GLY 800  
176 1 Y 1 A ARG 801  ? A ARG 801  
177 1 Y 1 A ASP 802  ? A ASP 802  
178 1 Y 1 A ARG 865  ? A ARG 865  
179 1 Y 1 A GLU 866  ? A GLU 866  
180 1 Y 1 A GLY 867  ? A GLY 867  
181 1 Y 1 A MET 868  ? A MET 868  
182 1 Y 1 A GLN 869  ? A GLN 869  
183 1 Y 1 A GLN 870  ? A GLN 870  
184 1 Y 1 A ALA 871  ? A ALA 871  
185 1 Y 1 A GLY 872  ? A GLY 872  
186 1 Y 1 A THR 873  ? A THR 873  
187 1 Y 1 A ALA 1080 ? A ALA 1080 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-25 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           8QY7 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Zorya anti-bacteriophage defense system ZorD apo form' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON II (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Novo Nordisk Foundation' Denmark NNF17OC0031006 1 
'Novo Nordisk Foundation' Denmark NNF21OC0071948 2 
Lundbeckfonden            Denmark R347-2020-2429 3 
# 
_atom_sites.entry_id                    8QY7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . LYS A 1 21   ? 172.234 205.763 166.520 1.00 36.98  ? 21   LYS A N   1 
ATOM 2    C CA  . LYS A 1 21   ? 170.816 205.750 166.860 1.00 38.84  ? 21   LYS A CA  1 
ATOM 3    C C   . LYS A 1 21   ? 170.274 204.325 166.906 1.00 38.94  ? 21   LYS A C   1 
ATOM 4    O O   . LYS A 1 21   ? 170.124 203.674 165.871 1.00 36.15  ? 21   LYS A O   1 
ATOM 5    C CB  . LYS A 1 21   ? 170.016 206.585 165.857 1.00 38.47  ? 21   LYS A CB  1 
ATOM 6    C CG  . LYS A 1 21   ? 168.506 206.426 165.970 1.00 37.86  ? 21   LYS A CG  1 
ATOM 7    C CD  . LYS A 1 21   ? 167.920 207.376 167.002 1.00 39.15  ? 21   LYS A CD  1 
ATOM 8    C CE  . LYS A 1 21   ? 166.541 206.918 167.452 1.00 39.17  ? 21   LYS A CE  1 
ATOM 9    N NZ  . LYS A 1 21   ? 166.315 207.169 168.901 1.00 37.34  ? 21   LYS A NZ  1 
ATOM 10   N N   . ASN A 1 22   ? 169.993 203.842 168.113 1.00 36.74  ? 22   ASN A N   1 
ATOM 11   C CA  . ASN A 1 22   ? 169.383 202.529 168.265 1.00 32.76  ? 22   ASN A CA  1 
ATOM 12   C C   . ASN A 1 22   ? 167.964 202.543 167.715 1.00 30.36  ? 22   ASN A C   1 
ATOM 13   O O   . ASN A 1 22   ? 167.190 203.470 167.969 1.00 30.36  ? 22   ASN A O   1 
ATOM 14   C CB  . ASN A 1 22   ? 169.372 202.109 169.734 1.00 31.26  ? 22   ASN A CB  1 
ATOM 15   C CG  . ASN A 1 22   ? 170.763 201.860 170.279 1.00 34.24  ? 22   ASN A CG  1 
ATOM 16   O OD1 . ASN A 1 22   ? 171.631 201.335 169.582 1.00 37.94  ? 22   ASN A OD1 1 
ATOM 17   N ND2 . ASN A 1 22   ? 170.984 202.240 171.533 1.00 30.75  ? 22   ASN A ND2 1 
ATOM 18   N N   . GLN A 1 23   ? 167.623 201.507 166.953 1.00 26.81  ? 23   GLN A N   1 
ATOM 19   C CA  . GLN A 1 23   ? 166.294 201.399 166.371 1.00 28.28  ? 23   GLN A CA  1 
ATOM 20   C C   . GLN A 1 23   ? 165.316 200.639 167.254 1.00 25.14  ? 23   GLN A C   1 
ATOM 21   O O   . GLN A 1 23   ? 164.144 200.513 166.885 1.00 27.97  ? 23   GLN A O   1 
ATOM 22   C CB  . GLN A 1 23   ? 166.369 200.726 164.997 1.00 24.99  ? 23   GLN A CB  1 
ATOM 23   C CG  . GLN A 1 23   ? 167.124 201.534 163.956 1.00 23.18  ? 23   GLN A CG  1 
ATOM 24   C CD  . GLN A 1 23   ? 166.463 202.865 163.667 1.00 28.24  ? 23   GLN A CD  1 
ATOM 25   O OE1 . GLN A 1 23   ? 166.978 203.920 164.035 1.00 30.91  ? 23   GLN A OE1 1 
ATOM 26   N NE2 . GLN A 1 23   ? 165.309 202.823 163.015 1.00 26.02  ? 23   GLN A NE2 1 
ATOM 27   N N   . TYR A 1 24   ? 165.759 200.138 168.402 1.00 19.94  ? 24   TYR A N   1 
ATOM 28   C CA  . TYR A 1 24   ? 164.885 199.426 169.320 1.00 14.12  ? 24   TYR A CA  1 
ATOM 29   C C   . TYR A 1 24   ? 164.557 200.293 170.529 1.00 20.52  ? 24   TYR A C   1 
ATOM 30   O O   . TYR A 1 24   ? 165.306 201.204 170.888 1.00 26.68  ? 24   TYR A O   1 
ATOM 31   C CB  . TYR A 1 24   ? 165.514 198.099 169.768 1.00 16.48  ? 24   TYR A CB  1 
ATOM 32   C CG  . TYR A 1 24   ? 166.862 198.203 170.459 1.00 17.62  ? 24   TYR A CG  1 
ATOM 33   C CD1 . TYR A 1 24   ? 166.984 198.756 171.728 1.00 18.63  ? 24   TYR A CD1 1 
ATOM 34   C CD2 . TYR A 1 24   ? 168.012 197.733 169.842 1.00 18.50  ? 24   TYR A CD2 1 
ATOM 35   C CE1 . TYR A 1 24   ? 168.206 198.847 172.355 1.00 18.85  ? 24   TYR A CE1 1 
ATOM 36   C CE2 . TYR A 1 24   ? 169.242 197.819 170.463 1.00 22.01  ? 24   TYR A CE2 1 
ATOM 37   C CZ  . TYR A 1 24   ? 169.332 198.376 171.719 1.00 24.43  ? 24   TYR A CZ  1 
ATOM 38   O OH  . TYR A 1 24   ? 170.554 198.465 172.343 1.00 25.26  ? 24   TYR A OH  1 
ATOM 39   N N   . GLN A 1 25   ? 163.419 200.001 171.148 1.00 17.47  ? 25   GLN A N   1 
ATOM 40   C CA  . GLN A 1 25   ? 163.012 200.629 172.397 1.00 15.41  ? 25   GLN A CA  1 
ATOM 41   C C   . GLN A 1 25   ? 163.128 199.597 173.509 1.00 15.14  ? 25   GLN A C   1 
ATOM 42   O O   . GLN A 1 25   ? 162.522 198.523 173.429 1.00 22.53  ? 25   GLN A O   1 
ATOM 43   C CB  . GLN A 1 25   ? 161.585 201.168 172.308 1.00 16.67  ? 25   GLN A CB  1 
ATOM 44   C CG  . GLN A 1 25   ? 161.402 202.278 171.288 1.00 24.65  ? 25   GLN A CG  1 
ATOM 45   C CD  . GLN A 1 25   ? 162.156 203.540 171.660 1.00 24.38  ? 25   GLN A CD  1 
ATOM 46   O OE1 . GLN A 1 25   ? 162.221 203.916 172.830 1.00 23.05  ? 25   GLN A OE1 1 
ATOM 47   N NE2 . GLN A 1 25   ? 162.732 204.200 170.663 1.00 21.58  ? 25   GLN A NE2 1 
ATOM 48   N N   . VAL A 1 26   ? 163.906 199.919 174.535 1.00 15.87  ? 26   VAL A N   1 
ATOM 49   C CA  . VAL A 1 26   ? 164.067 199.028 175.677 1.00 16.50  ? 26   VAL A CA  1 
ATOM 50   C C   . VAL A 1 26   ? 162.831 199.125 176.557 1.00 23.36  ? 26   VAL A C   1 
ATOM 51   O O   . VAL A 1 26   ? 162.410 200.223 176.941 1.00 24.78  ? 26   VAL A O   1 
ATOM 52   C CB  . VAL A 1 26   ? 165.337 199.377 176.468 1.00 16.29  ? 26   VAL A CB  1 
ATOM 53   C CG1 . VAL A 1 26   ? 165.569 198.356 177.567 1.00 14.49  ? 26   VAL A CG1 1 
ATOM 54   C CG2 . VAL A 1 26   ? 166.536 199.450 175.539 1.00 18.69  ? 26   VAL A CG2 1 
ATOM 55   N N   . GLU A 1 27   ? 162.241 197.975 176.877 1.00 18.10  ? 27   GLU A N   1 
ATOM 56   C CA  . GLU A 1 27   ? 161.108 197.948 177.791 1.00 21.63  ? 27   GLU A CA  1 
ATOM 57   C C   . GLU A 1 27   ? 161.189 196.731 178.704 1.00 19.96  ? 27   GLU A C   1 
ATOM 58   O O   . GLU A 1 27   ? 162.205 196.031 178.722 1.00 22.25  ? 27   GLU A O   1 
ATOM 59   C CB  . GLU A 1 27   ? 159.789 197.975 177.016 1.00 23.36  ? 27   GLU A CB  1 
ATOM 60   C CG  . GLU A 1 27   ? 159.517 196.759 176.157 1.00 19.72  ? 27   GLU A CG  1 
ATOM 61   C CD  . GLU A 1 27   ? 158.227 196.901 175.377 1.00 27.65  ? 27   GLU A CD  1 
ATOM 62   O OE1 . GLU A 1 27   ? 157.574 197.958 175.501 1.00 29.40  ? 27   GLU A OE1 1 
ATOM 63   O OE2 . GLU A 1 27   ? 157.858 195.962 174.647 1.00 26.80  ? 27   GLU A OE2 1 
ATOM 64   N N   . GLU A 1 28   ? 160.130 196.475 179.470 1.00 25.30  ? 28   GLU A N   1 
ATOM 65   C CA  . GLU A 1 28   ? 160.187 195.473 180.525 1.00 21.74  ? 28   GLU A CA  1 
ATOM 66   C C   . GLU A 1 28   ? 160.096 194.042 180.012 1.00 21.45  ? 28   GLU A C   1 
ATOM 67   O O   . GLU A 1 28   ? 160.339 193.112 180.788 1.00 27.32  ? 28   GLU A O   1 
ATOM 68   C CB  . GLU A 1 28   ? 159.069 195.722 181.541 1.00 24.52  ? 28   GLU A CB  1 
ATOM 69   C CG  . GLU A 1 28   ? 159.220 197.019 182.320 1.00 28.60  ? 28   GLU A CG  1 
ATOM 70   C CD  . GLU A 1 28   ? 160.425 197.017 183.241 1.00 32.44  ? 28   GLU A CD  1 
ATOM 71   O OE1 . GLU A 1 28   ? 160.789 195.936 183.749 1.00 29.93  ? 28   GLU A OE1 1 
ATOM 72   O OE2 . GLU A 1 28   ? 161.007 198.101 183.458 1.00 31.76  ? 28   GLU A OE2 1 
ATOM 73   N N   . ASN A 1 29   ? 159.759 193.835 178.740 1.00 16.96  ? 29   ASN A N   1 
ATOM 74   C CA  . ASN A 1 29   ? 159.611 192.493 178.200 1.00 16.16  ? 29   ASN A CA  1 
ATOM 75   C C   . ASN A 1 29   ? 160.595 192.151 177.092 1.00 19.38  ? 29   ASN A C   1 
ATOM 76   O O   . ASN A 1 29   ? 160.664 190.983 176.697 1.00 22.79  ? 29   ASN A O   1 
ATOM 77   C CB  . ASN A 1 29   ? 158.182 192.281 177.677 1.00 21.38  ? 29   ASN A CB  1 
ATOM 78   C CG  . ASN A 1 29   ? 157.143 192.365 178.775 1.00 27.19  ? 29   ASN A CG  1 
ATOM 79   O OD1 . ASN A 1 29   ? 156.307 193.268 178.787 1.00 31.63  ? 29   ASN A OD1 1 
ATOM 80   N ND2 . ASN A 1 29   ? 157.190 191.420 179.706 1.00 22.70  ? 29   ASN A ND2 1 
ATOM 81   N N   . GLY A 1 30   ? 161.352 193.114 176.583 1.00 17.66  ? 30   GLY A N   1 
ATOM 82   C CA  . GLY A 1 30   ? 162.324 192.822 175.547 1.00 9.77   ? 30   GLY A CA  1 
ATOM 83   C C   . GLY A 1 30   ? 162.646 194.070 174.745 1.00 12.18  ? 30   GLY A C   1 
ATOM 84   O O   . GLY A 1 30   ? 162.430 195.190 175.202 1.00 20.29  ? 30   GLY A O   1 
ATOM 85   N N   . LEU A 1 31   ? 163.175 193.840 173.548 1.00 11.45  ? 31   LEU A N   1 
ATOM 86   C CA  . LEU A 1 31   ? 163.473 194.905 172.601 1.00 10.46  ? 31   LEU A CA  1 
ATOM 87   C C   . LEU A 1 31   ? 162.268 195.132 171.702 1.00 15.30  ? 31   LEU A C   1 
ATOM 88   O O   . LEU A 1 31   ? 161.631 194.173 171.255 1.00 25.68  ? 31   LEU A O   1 
ATOM 89   C CB  . LEU A 1 31   ? 164.706 194.569 171.762 1.00 18.82  ? 31   LEU A CB  1 
ATOM 90   C CG  . LEU A 1 31   ? 165.965 194.283 172.574 1.00 16.87  ? 31   LEU A CG  1 
ATOM 91   C CD1 . LEU A 1 31   ? 167.115 193.869 171.681 1.00 19.27  ? 31   LEU A CD1 1 
ATOM 92   C CD2 . LEU A 1 31   ? 166.319 195.524 173.341 1.00 9.59   ? 31   LEU A CD2 1 
ATOM 93   N N   . SER A 1 32   ? 161.960 196.396 171.444 1.00 9.39   ? 32   SER A N   1 
ATOM 94   C CA  . SER A 1 32   ? 160.774 196.789 170.698 1.00 8.18   ? 32   SER A CA  1 
ATOM 95   C C   . SER A 1 32   ? 161.179 197.419 169.375 1.00 14.59  ? 32   SER A C   1 
ATOM 96   O O   . SER A 1 32   ? 161.972 198.364 169.351 1.00 16.35  ? 32   SER A O   1 
ATOM 97   C CB  . SER A 1 32   ? 159.929 197.766 171.513 1.00 15.93  ? 32   SER A CB  1 
ATOM 98   O OG  . SER A 1 32   ? 158.936 198.348 170.713 1.00 23.64  ? 32   SER A OG  1 
ATOM 99   N N   . PHE A 1 33   ? 160.625 196.902 168.283 1.00 13.50  ? 33   PHE A N   1 
ATOM 100  C CA  . PHE A 1 33   ? 160.868 197.426 166.954 1.00 12.56  ? 33   PHE A CA  1 
ATOM 101  C C   . PHE A 1 33   ? 159.546 197.819 166.314 1.00 16.69  ? 33   PHE A C   1 
ATOM 102  O O   . PHE A 1 33   ? 158.613 197.003 166.285 1.00 22.65  ? 33   PHE A O   1 
ATOM 103  C CB  . PHE A 1 33   ? 161.584 196.389 166.078 1.00 13.72  ? 33   PHE A CB  1 
ATOM 104  C CG  . PHE A 1 33   ? 162.984 196.089 166.517 1.00 8.11   ? 33   PHE A CG  1 
ATOM 105  C CD1 . PHE A 1 33   ? 163.256 194.974 167.290 1.00 2.63   ? 33   PHE A CD1 1 
ATOM 106  C CD2 . PHE A 1 33   ? 164.030 196.915 166.149 1.00 8.48   ? 33   PHE A CD2 1 
ATOM 107  C CE1 . PHE A 1 33   ? 164.542 194.695 167.695 1.00 9.96   ? 33   PHE A CE1 1 
ATOM 108  C CE2 . PHE A 1 33   ? 165.320 196.639 166.548 1.00 11.90  ? 33   PHE A CE2 1 
ATOM 109  C CZ  . PHE A 1 33   ? 165.574 195.527 167.323 1.00 13.62  ? 33   PHE A CZ  1 
ATOM 110  N N   . PRO A 1 34   ? 159.417 199.036 165.797 1.00 17.29  ? 34   PRO A N   1 
ATOM 111  C CA  . PRO A 1 34   ? 158.151 199.440 165.182 1.00 15.67  ? 34   PRO A CA  1 
ATOM 112  C C   . PRO A 1 34   ? 157.912 198.712 163.871 1.00 20.99  ? 34   PRO A C   1 
ATOM 113  O O   . PRO A 1 34   ? 158.846 198.334 163.158 1.00 25.10  ? 34   PRO A O   1 
ATOM 114  C CB  . PRO A 1 34   ? 158.333 200.943 164.961 1.00 21.78  ? 34   PRO A CB  1 
ATOM 115  C CG  . PRO A 1 34   ? 159.796 201.101 164.745 1.00 19.07  ? 34   PRO A CG  1 
ATOM 116  C CD  . PRO A 1 34   ? 160.486 200.024 165.558 1.00 19.57  ? 34   PRO A CD  1 
ATOM 117  N N   . LEU A 1 35   ? 156.632 198.518 163.557 1.00 25.25  ? 35   LEU A N   1 
ATOM 118  C CA  . LEU A 1 35   ? 156.248 197.882 162.305 1.00 27.05  ? 35   LEU A CA  1 
ATOM 119  C C   . LEU A 1 35   ? 156.480 198.781 161.098 1.00 28.67  ? 35   LEU A C   1 
ATOM 120  O O   . LEU A 1 35   ? 156.340 198.313 159.963 1.00 29.63  ? 35   LEU A O   1 
ATOM 121  C CB  . LEU A 1 35   ? 154.778 197.460 162.363 1.00 24.29  ? 35   LEU A CB  1 
ATOM 122  C CG  . LEU A 1 35   ? 154.443 196.290 163.290 1.00 23.00  ? 35   LEU A CG  1 
ATOM 123  C CD1 . LEU A 1 35   ? 153.007 195.836 163.086 1.00 27.34  ? 35   LEU A CD1 1 
ATOM 124  C CD2 . LEU A 1 35   ? 155.405 195.137 163.072 1.00 24.20  ? 35   LEU A CD2 1 
ATOM 125  N N   . SER A 1 36   ? 156.825 200.049 161.315 1.00 25.94  ? 36   SER A N   1 
ATOM 126  C CA  . SER A 1 36   ? 157.013 201.009 160.236 1.00 29.67  ? 36   SER A CA  1 
ATOM 127  C C   . SER A 1 36   ? 158.433 201.031 159.685 1.00 30.44  ? 36   SER A C   1 
ATOM 128  O O   . SER A 1 36   ? 158.702 201.802 158.758 1.00 28.63  ? 36   SER A O   1 
ATOM 129  C CB  . SER A 1 36   ? 156.630 202.412 160.714 1.00 32.85  ? 36   SER A CB  1 
ATOM 130  O OG  . SER A 1 36   ? 157.260 202.719 161.946 1.00 29.92  ? 36   SER A OG  1 
ATOM 131  N N   . LEU A 1 37   ? 159.348 200.221 160.225 1.00 28.71  ? 37   LEU A N   1 
ATOM 132  C CA  . LEU A 1 37   ? 160.697 200.176 159.670 1.00 27.88  ? 37   LEU A CA  1 
ATOM 133  C C   . LEU A 1 37   ? 160.707 199.582 158.269 1.00 33.12  ? 37   LEU A C   1 
ATOM 134  O O   . LEU A 1 37   ? 161.635 199.837 157.494 1.00 33.21  ? 37   LEU A O   1 
ATOM 135  C CB  . LEU A 1 37   ? 161.628 199.384 160.589 1.00 20.79  ? 37   LEU A CB  1 
ATOM 136  C CG  . LEU A 1 37   ? 161.899 200.001 161.962 1.00 30.14  ? 37   LEU A CG  1 
ATOM 137  C CD1 . LEU A 1 37   ? 162.718 199.063 162.828 1.00 27.13  ? 37   LEU A CD1 1 
ATOM 138  C CD2 . LEU A 1 37   ? 162.601 201.337 161.808 1.00 31.29  ? 37   LEU A CD2 1 
ATOM 139  N N   . VAL A 1 38   ? 159.691 198.785 157.929 1.00 29.98  ? 38   VAL A N   1 
ATOM 140  C CA  . VAL A 1 38   ? 159.593 198.248 156.576 1.00 28.95  ? 38   VAL A CA  1 
ATOM 141  C C   . VAL A 1 38   ? 159.370 199.370 155.571 1.00 29.82  ? 38   VAL A C   1 
ATOM 142  O O   . VAL A 1 38   ? 159.922 199.342 154.464 1.00 29.55  ? 38   VAL A O   1 
ATOM 143  C CB  . VAL A 1 38   ? 158.478 197.188 156.506 1.00 31.17  ? 38   VAL A CB  1 
ATOM 144  C CG1 . VAL A 1 38   ? 158.296 196.695 155.078 1.00 27.42  ? 38   VAL A CG1 1 
ATOM 145  C CG2 . VAL A 1 38   ? 158.790 196.030 157.442 1.00 27.83  ? 38   VAL A CG2 1 
ATOM 146  N N   . ASP A 1 39   ? 158.569 200.374 155.934 1.00 34.19  ? 39   ASP A N   1 
ATOM 147  C CA  . ASP A 1 39   ? 158.318 201.507 155.053 1.00 36.00  ? 39   ASP A CA  1 
ATOM 148  C C   . ASP A 1 39   ? 159.535 202.405 154.880 1.00 37.09  ? 39   ASP A C   1 
ATOM 149  O O   . ASP A 1 39   ? 159.528 203.262 153.990 1.00 37.28  ? 39   ASP A O   1 
ATOM 150  C CB  . ASP A 1 39   ? 157.145 202.333 155.583 1.00 36.48  ? 39   ASP A CB  1 
ATOM 151  C CG  . ASP A 1 39   ? 155.931 201.483 155.902 1.00 39.22  ? 39   ASP A CG  1 
ATOM 152  O OD1 . ASP A 1 39   ? 155.858 200.338 155.409 1.00 34.55  ? 39   ASP A OD1 1 
ATOM 153  O OD2 . ASP A 1 39   ? 155.051 201.960 156.649 1.00 40.60  ? 39   ASP A OD2 1 
ATOM 154  N N   . ASP A 1 40   ? 160.566 202.241 155.704 1.00 36.74  ? 40   ASP A N   1 
ATOM 155  C CA  . ASP A 1 40   ? 161.765 203.057 155.584 1.00 33.48  ? 40   ASP A CA  1 
ATOM 156  C C   . ASP A 1 40   ? 162.671 202.502 154.493 1.00 36.72  ? 40   ASP A C   1 
ATOM 157  O O   . ASP A 1 40   ? 162.794 201.285 154.327 1.00 33.72  ? 40   ASP A O   1 
ATOM 158  C CB  . ASP A 1 40   ? 162.508 203.111 156.918 1.00 32.18  ? 40   ASP A CB  1 
ATOM 159  C CG  . ASP A 1 40   ? 163.266 204.404 157.109 1.00 35.84  ? 40   ASP A CG  1 
ATOM 160  O OD1 . ASP A 1 40   ? 163.069 205.065 158.148 1.00 37.41  ? 40   ASP A OD1 1 
ATOM 161  O OD2 . ASP A 1 40   ? 164.052 204.752 156.224 1.00 37.04  ? 40   ASP A OD2 1 
ATOM 162  N N   . SER A 1 41   ? 163.307 203.405 153.748 1.00 40.48  ? 41   SER A N   1 
ATOM 163  C CA  . SER A 1 41   ? 164.099 203.014 152.589 1.00 36.92  ? 41   SER A CA  1 
ATOM 164  C C   . SER A 1 41   ? 165.573 202.803 152.904 1.00 30.86  ? 41   SER A C   1 
ATOM 165  O O   . SER A 1 41   ? 166.206 201.935 152.294 1.00 33.21  ? 41   SER A O   1 
ATOM 166  C CB  . SER A 1 41   ? 163.963 204.063 151.481 1.00 32.63  ? 41   SER A CB  1 
ATOM 167  O OG  . SER A 1 41   ? 164.538 205.297 151.874 1.00 38.06  ? 41   SER A OG  1 
ATOM 168  N N   . GLN A 1 42   ? 166.145 203.569 153.833 1.00 24.55  ? 42   GLN A N   1 
ATOM 169  C CA  . GLN A 1 42   ? 167.569 203.441 154.118 1.00 29.34  ? 42   GLN A CA  1 
ATOM 170  C C   . GLN A 1 42   ? 167.879 202.337 155.120 1.00 27.25  ? 42   GLN A C   1 
ATOM 171  O O   . GLN A 1 42   ? 169.057 202.092 155.397 1.00 29.15  ? 42   GLN A O   1 
ATOM 172  C CB  . GLN A 1 42   ? 168.150 204.768 154.625 1.00 28.07  ? 42   GLN A CB  1 
ATOM 173  C CG  . GLN A 1 42   ? 167.616 206.018 153.934 1.00 28.36  ? 42   GLN A CG  1 
ATOM 174  C CD  . GLN A 1 42   ? 166.245 206.424 154.428 1.00 32.58  ? 42   GLN A CD  1 
ATOM 175  O OE1 . GLN A 1 42   ? 165.863 206.087 155.536 1.00 32.93  ? 42   GLN A OE1 1 
ATOM 176  N NE2 . GLN A 1 42   ? 165.501 207.150 153.602 1.00 30.55  ? 42   GLN A NE2 1 
ATOM 177  N N   . LEU A 1 43   ? 166.862 201.670 155.663 1.00 15.37  ? 43   LEU A N   1 
ATOM 178  C CA  . LEU A 1 43   ? 167.078 200.555 156.577 1.00 14.06  ? 43   LEU A CA  1 
ATOM 179  C C   . LEU A 1 43   ? 166.456 199.282 156.019 1.00 14.38  ? 43   LEU A C   1 
ATOM 180  O O   . LEU A 1 43   ? 165.748 198.564 156.732 1.00 12.16  ? 43   LEU A O   1 
ATOM 181  C CB  . LEU A 1 43   ? 166.506 200.864 157.961 1.00 15.25  ? 43   LEU A CB  1 
ATOM 182  C CG  . LEU A 1 43   ? 166.938 202.184 158.597 1.00 14.85  ? 43   LEU A CG  1 
ATOM 183  C CD1 . LEU A 1 43   ? 166.131 202.449 159.849 1.00 14.09  ? 43   LEU A CD1 1 
ATOM 184  C CD2 . LEU A 1 43   ? 168.424 202.165 158.910 1.00 17.63  ? 43   LEU A CD2 1 
ATOM 185  N N   . TRP A 1 44   ? 166.709 199.007 154.737 1.00 13.28  ? 44   TRP A N   1 
ATOM 186  C CA  . TRP A 1 44   ? 166.158 197.811 154.108 1.00 5.53   ? 44   TRP A CA  1 
ATOM 187  C C   . TRP A 1 44   ? 166.687 196.544 154.767 1.00 6.79   ? 44   TRP A C   1 
ATOM 188  O O   . TRP A 1 44   ? 165.937 195.583 154.972 1.00 14.11  ? 44   TRP A O   1 
ATOM 189  C CB  . TRP A 1 44   ? 166.478 197.818 152.611 1.00 2.84   ? 44   TRP A CB  1 
ATOM 190  C CG  . TRP A 1 44   ? 167.944 197.926 152.308 1.00 3.10   ? 44   TRP A CG  1 
ATOM 191  C CD1 . TRP A 1 44   ? 168.651 199.071 152.092 1.00 7.55   ? 44   TRP A CD1 1 
ATOM 192  C CD2 . TRP A 1 44   ? 168.876 196.847 152.164 1.00 3.04   ? 44   TRP A CD2 1 
ATOM 193  N NE1 . TRP A 1 44   ? 169.967 198.774 151.839 1.00 10.12  ? 44   TRP A NE1 1 
ATOM 194  C CE2 . TRP A 1 44   ? 170.131 197.415 151.876 1.00 5.55   ? 44   TRP A CE2 1 
ATOM 195  C CE3 . TRP A 1 44   ? 168.771 195.455 152.256 1.00 1.27   ? 44   TRP A CE3 1 
ATOM 196  C CZ2 . TRP A 1 44   ? 171.272 196.642 151.680 1.00 7.26   ? 44   TRP A CZ2 1 
ATOM 197  C CZ3 . TRP A 1 44   ? 169.905 194.691 152.065 1.00 2.08   ? 44   TRP A CZ3 1 
ATOM 198  C CH2 . TRP A 1 44   ? 171.139 195.285 151.778 1.00 4.55   ? 44   TRP A CH2 1 
ATOM 199  N N   . ALA A 1 45   ? 167.979 196.523 155.106 1.00 2.95   ? 45   ALA A N   1 
ATOM 200  C CA  . ALA A 1 45   ? 168.570 195.334 155.710 1.00 0.00   ? 45   ALA A CA  1 
ATOM 201  C C   . ALA A 1 45   ? 167.958 195.044 157.073 1.00 2.05   ? 45   ALA A C   1 
ATOM 202  O O   . ALA A 1 45   ? 167.630 193.893 157.383 1.00 6.57   ? 45   ALA A O   1 
ATOM 203  C CB  . ALA A 1 45   ? 170.084 195.502 155.826 1.00 0.00   ? 45   ALA A CB  1 
ATOM 204  N N   . LEU A 1 46   ? 167.789 196.078 157.897 1.00 7.70   ? 46   LEU A N   1 
ATOM 205  C CA  . LEU A 1 46   ? 167.214 195.881 159.222 1.00 1.87   ? 46   LEU A CA  1 
ATOM 206  C C   . LEU A 1 46   ? 165.767 195.410 159.141 1.00 0.60   ? 46   LEU A C   1 
ATOM 207  O O   . LEU A 1 46   ? 165.372 194.484 159.856 1.00 3.62   ? 46   LEU A O   1 
ATOM 208  C CB  . LEU A 1 46   ? 167.317 197.173 160.030 1.00 5.26   ? 46   LEU A CB  1 
ATOM 209  C CG  . LEU A 1 46   ? 166.610 197.148 161.382 1.00 6.27   ? 46   LEU A CG  1 
ATOM 210  C CD1 . LEU A 1 46   ? 167.236 196.089 162.247 1.00 6.19   ? 46   LEU A CD1 1 
ATOM 211  C CD2 . LEU A 1 46   ? 166.694 198.502 162.050 1.00 8.82   ? 46   LEU A CD2 1 
ATOM 212  N N   . ALA A 1 47   ? 164.963 196.032 158.276 1.00 0.75   ? 47   ALA A N   1 
ATOM 213  C CA  . ALA A 1 47   ? 163.570 195.618 158.131 1.00 0.00   ? 47   ALA A CA  1 
ATOM 214  C C   . ALA A 1 47   ? 163.470 194.192 157.603 1.00 7.05   ? 47   ALA A C   1 
ATOM 215  O O   . ALA A 1 47   ? 162.629 193.406 158.061 1.00 12.38  ? 47   ALA A O   1 
ATOM 216  C CB  . ALA A 1 47   ? 162.830 196.586 157.211 1.00 3.70   ? 47   ALA A CB  1 
ATOM 217  N N   . SER A 1 48   ? 164.320 193.841 156.636 1.00 7.12   ? 48   SER A N   1 
ATOM 218  C CA  . SER A 1 48   ? 164.321 192.481 156.112 1.00 0.00   ? 48   SER A CA  1 
ATOM 219  C C   . SER A 1 48   ? 164.710 191.478 157.190 1.00 3.36   ? 48   SER A C   1 
ATOM 220  O O   . SER A 1 48   ? 164.124 190.394 157.280 1.00 6.86   ? 48   SER A O   1 
ATOM 221  C CB  . SER A 1 48   ? 165.264 192.383 154.914 1.00 0.07   ? 48   SER A CB  1 
ATOM 222  O OG  . SER A 1 48   ? 165.303 191.062 154.408 1.00 16.89  ? 48   SER A OG  1 
ATOM 223  N N   . TRP A 1 49   ? 165.692 191.823 158.026 1.00 2.55   ? 49   TRP A N   1 
ATOM 224  C CA  . TRP A 1 49   ? 166.081 190.916 159.099 1.00 0.00   ? 49   TRP A CA  1 
ATOM 225  C C   . TRP A 1 49   ? 164.982 190.784 160.146 1.00 0.00   ? 49   TRP A C   1 
ATOM 226  O O   . TRP A 1 49   ? 164.798 189.707 160.719 1.00 6.80   ? 49   TRP A O   1 
ATOM 227  C CB  . TRP A 1 49   ? 167.385 191.377 159.746 1.00 0.00   ? 49   TRP A CB  1 
ATOM 228  C CG  . TRP A 1 49   ? 167.902 190.398 160.750 1.00 0.00   ? 49   TRP A CG  1 
ATOM 229  C CD1 . TRP A 1 49   ? 168.062 189.056 160.574 1.00 2.31   ? 49   TRP A CD1 1 
ATOM 230  C CD2 . TRP A 1 49   ? 168.339 190.682 162.084 1.00 5.77   ? 49   TRP A CD2 1 
ATOM 231  N NE1 . TRP A 1 49   ? 168.563 188.484 161.716 1.00 3.71   ? 49   TRP A NE1 1 
ATOM 232  C CE2 . TRP A 1 49   ? 168.744 189.461 162.658 1.00 6.45   ? 49   TRP A CE2 1 
ATOM 233  C CE3 . TRP A 1 49   ? 168.424 191.848 162.849 1.00 2.69   ? 49   TRP A CE3 1 
ATOM 234  C CZ2 . TRP A 1 49   ? 169.228 189.374 163.960 1.00 5.01   ? 49   TRP A CZ2 1 
ATOM 235  C CZ3 . TRP A 1 49   ? 168.905 191.758 164.140 1.00 4.08   ? 49   TRP A CZ3 1 
ATOM 236  C CH2 . TRP A 1 49   ? 169.301 190.531 164.683 1.00 5.66   ? 49   TRP A CH2 1 
ATOM 237  N N   . LEU A 1 50   ? 164.251 191.865 160.424 1.00 0.14   ? 50   LEU A N   1 
ATOM 238  C CA  . LEU A 1 50   ? 163.118 191.750 161.339 1.00 5.44   ? 50   LEU A CA  1 
ATOM 239  C C   . LEU A 1 50   ? 162.029 190.857 160.761 1.00 7.69   ? 50   LEU A C   1 
ATOM 240  O O   . LEU A 1 50   ? 161.401 190.083 161.491 1.00 8.12   ? 50   LEU A O   1 
ATOM 241  C CB  . LEU A 1 50   ? 162.559 193.127 161.695 1.00 10.00  ? 50   LEU A CB  1 
ATOM 242  C CG  . LEU A 1 50   ? 163.540 194.130 162.298 1.00 2.94   ? 50   LEU A CG  1 
ATOM 243  C CD1 . LEU A 1 50   ? 162.968 195.531 162.239 1.00 9.20   ? 50   LEU A CD1 1 
ATOM 244  C CD2 . LEU A 1 50   ? 163.888 193.746 163.724 1.00 0.00   ? 50   LEU A CD2 1 
ATOM 245  N N   . GLU A 1 51   ? 161.785 190.946 159.451 1.00 9.84   ? 51   GLU A N   1 
ATOM 246  C CA  . GLU A 1 51   ? 160.850 190.010 158.830 1.00 5.31   ? 51   GLU A CA  1 
ATOM 247  C C   . GLU A 1 51   ? 161.353 188.574 158.936 1.00 4.78   ? 51   GLU A C   1 
ATOM 248  O O   . GLU A 1 51   ? 160.567 187.648 159.174 1.00 5.84   ? 51   GLU A O   1 
ATOM 249  C CB  . GLU A 1 51   ? 160.598 190.386 157.370 1.00 2.55   ? 51   GLU A CB  1 
ATOM 250  C CG  . GLU A 1 51   ? 159.854 191.695 157.187 1.00 7.13   ? 51   GLU A CG  1 
ATOM 251  C CD  . GLU A 1 51   ? 159.637 192.042 155.729 1.00 15.13  ? 51   GLU A CD  1 
ATOM 252  O OE1 . GLU A 1 51   ? 160.176 191.327 154.859 1.00 19.57  ? 51   GLU A OE1 1 
ATOM 253  O OE2 . GLU A 1 51   ? 158.920 193.026 155.451 1.00 13.90  ? 51   GLU A OE2 1 
ATOM 254  N N   . GLN A 1 52   ? 162.661 188.369 158.764 1.00 6.00   ? 52   GLN A N   1 
ATOM 255  C CA  . GLN A 1 52   ? 163.234 187.032 158.918 1.00 4.28   ? 52   GLN A CA  1 
ATOM 256  C C   . GLN A 1 52   ? 163.032 186.504 160.334 1.00 10.52  ? 52   GLN A C   1 
ATOM 257  O O   . GLN A 1 52   ? 162.654 185.343 160.530 1.00 19.96  ? 52   GLN A O   1 
ATOM 258  C CB  . GLN A 1 52   ? 164.722 187.050 158.568 1.00 5.45   ? 52   GLN A CB  1 
ATOM 259  C CG  . GLN A 1 52   ? 165.034 187.345 157.115 1.00 5.32   ? 52   GLN A CG  1 
ATOM 260  C CD  . GLN A 1 52   ? 166.513 187.568 156.876 1.00 0.90   ? 52   GLN A CD  1 
ATOM 261  O OE1 . GLN A 1 52   ? 167.231 188.043 157.754 1.00 9.54   ? 52   GLN A OE1 1 
ATOM 262  N NE2 . GLN A 1 52   ? 166.976 187.225 155.683 1.00 2.02   ? 52   GLN A NE2 1 
ATOM 263  N N   . LEU A 1 53   ? 163.288 187.345 161.337 1.00 8.28   ? 53   LEU A N   1 
ATOM 264  C CA  . LEU A 1 53   ? 163.128 186.922 162.726 1.00 3.44   ? 53   LEU A CA  1 
ATOM 265  C C   . LEU A 1 53   ? 161.667 186.647 163.056 1.00 6.30   ? 53   LEU A C   1 
ATOM 266  O O   . LEU A 1 53   ? 161.358 185.702 163.791 1.00 11.25  ? 53   LEU A O   1 
ATOM 267  C CB  . LEU A 1 53   ? 163.702 187.976 163.671 1.00 4.59   ? 53   LEU A CB  1 
ATOM 268  C CG  . LEU A 1 53   ? 165.192 188.288 163.538 1.00 0.00   ? 53   LEU A CG  1 
ATOM 269  C CD1 . LEU A 1 53   ? 165.565 189.480 164.400 1.00 1.85   ? 53   LEU A CD1 1 
ATOM 270  C CD2 . LEU A 1 53   ? 166.027 187.076 163.905 1.00 0.93   ? 53   LEU A CD2 1 
ATOM 271  N N   . ALA A 1 54   ? 160.755 187.468 162.533 1.00 9.09   ? 54   ALA A N   1 
ATOM 272  C CA  . ALA A 1 54   ? 159.332 187.223 162.743 1.00 7.95   ? 54   ALA A CA  1 
ATOM 273  C C   . ALA A 1 54   ? 158.907 185.903 162.116 1.00 15.52  ? 54   ALA A C   1 
ATOM 274  O O   . ALA A 1 54   ? 158.119 185.153 162.703 1.00 15.76  ? 54   ALA A O   1 
ATOM 275  C CB  . ALA A 1 54   ? 158.510 188.378 162.174 1.00 6.20   ? 54   ALA A CB  1 
ATOM 276  N N   . GLU A 1 55   ? 159.417 185.604 160.920 1.00 16.66  ? 55   GLU A N   1 
ATOM 277  C CA  . GLU A 1 55   ? 159.118 184.324 160.288 1.00 8.78   ? 55   GLU A CA  1 
ATOM 278  C C   . GLU A 1 55   ? 159.731 183.160 161.058 1.00 11.58  ? 55   GLU A C   1 
ATOM 279  O O   . GLU A 1 55   ? 159.132 182.081 161.129 1.00 21.86  ? 55   GLU A O   1 
ATOM 280  C CB  . GLU A 1 55   ? 159.606 184.337 158.838 1.00 9.85   ? 55   GLU A CB  1 
ATOM 281  C CG  . GLU A 1 55   ? 159.519 183.000 158.125 1.00 12.47  ? 55   GLU A CG  1 
ATOM 282  C CD  . GLU A 1 55   ? 160.853 182.288 158.069 1.00 21.31  ? 55   GLU A CD  1 
ATOM 283  O OE1 . GLU A 1 55   ? 160.864 181.040 158.081 1.00 28.49  ? 55   GLU A OE1 1 
ATOM 284  O OE2 . GLU A 1 55   ? 161.892 182.978 158.010 1.00 20.77  ? 55   GLU A OE2 1 
ATOM 285  N N   . GLU A 1 56   ? 160.907 183.359 161.650 1.00 12.25  ? 56   GLU A N   1 
ATOM 286  C CA  . GLU A 1 56   ? 161.608 182.315 162.386 1.00 12.83  ? 56   GLU A CA  1 
ATOM 287  C C   . GLU A 1 56   ? 161.219 182.259 163.859 1.00 17.84  ? 56   GLU A C   1 
ATOM 288  O O   . GLU A 1 56   ? 161.894 181.576 164.636 1.00 17.68  ? 56   GLU A O   1 
ATOM 289  C CB  . GLU A 1 56   ? 163.120 182.508 162.261 1.00 10.81  ? 56   GLU A CB  1 
ATOM 290  C CG  . GLU A 1 56   ? 163.681 182.139 160.902 1.00 10.13  ? 56   GLU A CG  1 
ATOM 291  C CD  . GLU A 1 56   ? 165.157 182.445 160.786 1.00 12.46  ? 56   GLU A CD  1 
ATOM 292  O OE1 . GLU A 1 56   ? 165.912 182.094 161.715 1.00 15.87  ? 56   GLU A OE1 1 
ATOM 293  O OE2 . GLU A 1 56   ? 165.563 183.040 159.767 1.00 15.74  ? 56   GLU A OE2 1 
ATOM 294  N N   . ASP A 1 57   ? 160.164 182.975 164.256 1.00 14.37  ? 57   ASP A N   1 
ATOM 295  C CA  . ASP A 1 57   ? 159.624 182.936 165.618 1.00 12.04  ? 57   ASP A CA  1 
ATOM 296  C C   . ASP A 1 57   ? 160.599 183.519 166.639 1.00 13.57  ? 57   ASP A C   1 
ATOM 297  O O   . ASP A 1 57   ? 160.735 183.005 167.749 1.00 21.21  ? 57   ASP A O   1 
ATOM 298  C CB  . ASP A 1 57   ? 159.207 181.518 166.017 1.00 13.61  ? 57   ASP A CB  1 
ATOM 299  C CG  . ASP A 1 57   ? 158.091 180.983 165.155 1.00 25.62  ? 57   ASP A CG  1 
ATOM 300  O OD1 . ASP A 1 57   ? 157.245 181.795 164.728 1.00 30.47  ? 57   ASP A OD1 1 
ATOM 301  O OD2 . ASP A 1 57   ? 158.060 179.761 164.904 1.00 25.80  ? 57   ASP A OD2 1 
ATOM 302  N N   . TYR A 1 58   ? 161.280 184.600 166.264 1.00 10.93  ? 58   TYR A N   1 
ATOM 303  C CA  . TYR A 1 58   ? 162.069 185.367 167.216 1.00 7.63   ? 58   TYR A CA  1 
ATOM 304  C C   . TYR A 1 58   ? 161.379 186.646 167.663 1.00 11.39  ? 58   TYR A C   1 
ATOM 305  O O   . TYR A 1 58   ? 161.654 187.126 168.768 1.00 21.30  ? 58   TYR A O   1 
ATOM 306  C CB  . TYR A 1 58   ? 163.437 185.724 166.621 1.00 6.99   ? 58   TYR A CB  1 
ATOM 307  C CG  . TYR A 1 58   ? 164.477 184.641 166.774 1.00 8.35   ? 58   TYR A CG  1 
ATOM 308  C CD1 . TYR A 1 58   ? 165.121 184.438 167.986 1.00 8.68   ? 58   TYR A CD1 1 
ATOM 309  C CD2 . TYR A 1 58   ? 164.829 183.833 165.702 1.00 5.62   ? 58   TYR A CD2 1 
ATOM 310  C CE1 . TYR A 1 58   ? 166.073 183.452 168.130 1.00 13.15  ? 58   TYR A CE1 1 
ATOM 311  C CE2 . TYR A 1 58   ? 165.785 182.846 165.837 1.00 6.63   ? 58   TYR A CE2 1 
ATOM 312  C CZ  . TYR A 1 58   ? 166.404 182.661 167.053 1.00 15.43  ? 58   TYR A CZ  1 
ATOM 313  O OH  . TYR A 1 58   ? 167.357 181.680 167.195 1.00 13.92  ? 58   TYR A OH  1 
ATOM 314  N N   . LEU A 1 59   ? 160.489 187.197 166.843 1.00 7.45   ? 59   LEU A N   1 
ATOM 315  C CA  . LEU A 1 59   ? 159.773 188.421 167.160 1.00 8.17   ? 59   LEU A CA  1 
ATOM 316  C C   . LEU A 1 59   ? 158.291 188.127 167.348 1.00 12.60  ? 59   LEU A C   1 
ATOM 317  O O   . LEU A 1 59   ? 157.745 187.188 166.763 1.00 14.15  ? 59   LEU A O   1 
ATOM 318  C CB  . LEU A 1 59   ? 159.954 189.472 166.061 1.00 4.43   ? 59   LEU A CB  1 
ATOM 319  C CG  . LEU A 1 59   ? 161.386 189.904 165.749 1.00 7.72   ? 59   LEU A CG  1 
ATOM 320  C CD1 . LEU A 1 59   ? 161.405 190.873 164.584 1.00 10.56  ? 59   LEU A CD1 1 
ATOM 321  C CD2 . LEU A 1 59   ? 162.034 190.528 166.964 1.00 7.77   ? 59   LEU A CD2 1 
ATOM 322  N N   . ILE A 1 60   ? 157.648 188.945 168.177 1.00 17.57  ? 60   ILE A N   1 
ATOM 323  C CA  . ILE A 1 60   ? 156.229 188.821 168.485 1.00 15.54  ? 60   ILE A CA  1 
ATOM 324  C C   . ILE A 1 60   ? 155.542 190.113 168.070 1.00 24.74  ? 60   ILE A C   1 
ATOM 325  O O   . ILE A 1 60   ? 155.976 191.203 168.458 1.00 27.69  ? 60   ILE A O   1 
ATOM 326  C CB  . ILE A 1 60   ? 155.999 188.536 169.980 1.00 17.91  ? 60   ILE A CB  1 
ATOM 327  C CG1 . ILE A 1 60   ? 156.622 187.195 170.370 1.00 23.97  ? 60   ILE A CG1 1 
ATOM 328  C CG2 . ILE A 1 60   ? 154.515 188.542 170.301 1.00 19.33  ? 60   ILE A CG2 1 
ATOM 329  C CD1 . ILE A 1 60   ? 156.669 186.958 171.864 1.00 20.47  ? 60   ILE A CD1 1 
ATOM 330  N N   . SER A 1 61   ? 154.475 189.991 167.286 1.00 25.39  ? 61   SER A N   1 
ATOM 331  C CA  . SER A 1 61   ? 153.717 191.148 166.830 1.00 26.48  ? 61   SER A CA  1 
ATOM 332  C C   . SER A 1 61   ? 152.701 191.549 167.891 1.00 28.51  ? 61   SER A C   1 
ATOM 333  O O   . SER A 1 61   ? 151.952 190.705 168.393 1.00 30.64  ? 61   SER A O   1 
ATOM 334  C CB  . SER A 1 61   ? 153.012 190.847 165.507 1.00 27.29  ? 61   SER A CB  1 
ATOM 335  O OG  . SER A 1 61   ? 152.253 191.960 165.071 1.00 31.80  ? 61   SER A OG  1 
ATOM 336  N N   . LEU A 1 62   ? 152.679 192.839 168.230 1.00 28.57  ? 62   LEU A N   1 
ATOM 337  C CA  . LEU A 1 62   ? 151.796 193.367 169.263 1.00 32.93  ? 62   LEU A CA  1 
ATOM 338  C C   . LEU A 1 62   ? 150.814 194.390 168.701 1.00 34.85  ? 62   LEU A C   1 
ATOM 339  O O   . LEU A 1 62   ? 150.334 195.259 169.432 1.00 32.46  ? 62   LEU A O   1 
ATOM 340  C CB  . LEU A 1 62   ? 152.606 193.974 170.407 1.00 28.25  ? 62   LEU A CB  1 
ATOM 341  C CG  . LEU A 1 62   ? 153.680 193.075 171.020 1.00 30.85  ? 62   LEU A CG  1 
ATOM 342  C CD1 . LEU A 1 62   ? 154.306 193.738 172.235 1.00 28.82  ? 62   LEU A CD1 1 
ATOM 343  C CD2 . LEU A 1 62   ? 153.088 191.727 171.393 1.00 27.39  ? 62   LEU A CD2 1 
ATOM 344  N N   . THR A 1 63   ? 150.524 194.294 167.398 1.00 36.41  ? 63   THR A N   1 
ATOM 345  C CA  . THR A 1 63   ? 149.532 195.096 166.680 1.00 38.14  ? 63   THR A CA  1 
ATOM 346  C C   . THR A 1 63   ? 150.048 196.512 166.407 1.00 35.67  ? 63   THR A C   1 
ATOM 347  O O   . THR A 1 63   ? 149.450 197.258 165.625 1.00 38.37  ? 63   THR A O   1 
ATOM 348  C CB  . THR A 1 63   ? 148.198 195.106 167.455 1.00 36.77  ? 63   THR A CB  1 
ATOM 349  O OG1 . THR A 1 63   ? 147.721 193.761 167.586 1.00 38.34  ? 63   THR A OG1 1 
ATOM 350  C CG2 . THR A 1 63   ? 147.122 195.916 166.742 1.00 35.27  ? 63   THR A CG2 1 
ATOM 351  N N   . ASP A 1 64   ? 151.192 196.878 166.985 1.00 31.31  ? 64   ASP A N   1 
ATOM 352  C CA  . ASP A 1 64   ? 151.850 198.126 166.597 1.00 27.74  ? 64   ASP A CA  1 
ATOM 353  C C   . ASP A 1 64   ? 153.352 198.005 166.417 1.00 29.08  ? 64   ASP A C   1 
ATOM 354  O O   . ASP A 1 64   ? 153.964 198.952 165.910 1.00 29.87  ? 64   ASP A O   1 
ATOM 355  C CB  . ASP A 1 64   ? 151.572 199.239 167.617 1.00 28.60  ? 64   ASP A CB  1 
ATOM 356  C CG  . ASP A 1 64   ? 151.774 198.786 169.048 1.00 33.38  ? 64   ASP A CG  1 
ATOM 357  O OD1 . ASP A 1 64   ? 151.443 197.629 169.359 1.00 32.48  ? 64   ASP A OD1 1 
ATOM 358  O OD2 . ASP A 1 64   ? 152.260 199.594 169.868 1.00 31.58  ? 64   ASP A OD2 1 
ATOM 359  N N   . ARG A 1 65   ? 153.969 196.888 166.795 1.00 30.18  ? 65   ARG A N   1 
ATOM 360  C CA  . ARG A 1 65   ? 155.418 196.794 166.882 1.00 22.84  ? 65   ARG A CA  1 
ATOM 361  C C   . ARG A 1 65   ? 155.798 195.350 167.170 1.00 23.19  ? 65   ARG A C   1 
ATOM 362  O O   . ARG A 1 65   ? 155.001 194.574 167.702 1.00 25.43  ? 65   ARG A O   1 
ATOM 363  C CB  . ARG A 1 65   ? 155.955 197.731 167.969 1.00 21.78  ? 65   ARG A CB  1 
ATOM 364  C CG  . ARG A 1 65   ? 155.628 197.276 169.377 1.00 24.23  ? 65   ARG A CG  1 
ATOM 365  C CD  . ARG A 1 65   ? 156.228 198.199 170.410 1.00 25.37  ? 65   ARG A CD  1 
ATOM 366  N NE  . ARG A 1 65   ? 155.975 197.780 171.783 1.00 29.78  ? 65   ARG A NE  1 
ATOM 367  C CZ  . ARG A 1 65   ? 154.767 197.636 172.309 1.00 29.27  ? 65   ARG A CZ  1 
ATOM 368  N NH1 . ARG A 1 65   ? 153.675 197.907 171.614 1.00 27.94  ? 65   ARG A NH1 1 
ATOM 369  N NH2 . ARG A 1 65   ? 154.652 197.229 173.568 1.00 25.86  ? 65   ARG A NH2 1 
ATOM 370  N N   . TRP A 1 66   ? 157.026 194.998 166.803 1.00 21.90  ? 66   TRP A N   1 
ATOM 371  C CA  . TRP A 1 66   ? 157.570 193.691 167.138 1.00 15.19  ? 66   TRP A CA  1 
ATOM 372  C C   . TRP A 1 66   ? 158.210 193.722 168.518 1.00 17.80  ? 66   TRP A C   1 
ATOM 373  O O   . TRP A 1 66   ? 158.727 194.750 168.964 1.00 18.39  ? 66   TRP A O   1 
ATOM 374  C CB  . TRP A 1 66   ? 158.609 193.227 166.116 1.00 17.07  ? 66   TRP A CB  1 
ATOM 375  C CG  . TRP A 1 66   ? 158.046 192.631 164.864 1.00 22.46  ? 66   TRP A CG  1 
ATOM 376  C CD1 . TRP A 1 66   ? 157.305 191.490 164.763 1.00 21.02  ? 66   TRP A CD1 1 
ATOM 377  C CD2 . TRP A 1 66   ? 158.243 193.100 163.526 1.00 15.06  ? 66   TRP A CD2 1 
ATOM 378  N NE1 . TRP A 1 66   ? 156.994 191.242 163.449 1.00 16.72  ? 66   TRP A NE1 1 
ATOM 379  C CE2 . TRP A 1 66   ? 157.562 192.213 162.669 1.00 16.24  ? 66   TRP A CE2 1 
ATOM 380  C CE3 . TRP A 1 66   ? 158.915 194.192 162.970 1.00 16.55  ? 66   TRP A CE3 1 
ATOM 381  C CZ2 . TRP A 1 66   ? 157.534 192.385 161.287 1.00 19.36  ? 66   TRP A CZ2 1 
ATOM 382  C CZ3 . TRP A 1 66   ? 158.885 194.361 161.598 1.00 22.88  ? 66   TRP A CZ3 1 
ATOM 383  C CH2 . TRP A 1 66   ? 158.200 193.463 160.773 1.00 21.48  ? 66   TRP A CH2 1 
ATOM 384  N N   . LEU A 1 67   ? 158.173 192.576 169.191 1.00 14.69  ? 67   LEU A N   1 
ATOM 385  C CA  . LEU A 1 67   ? 158.833 192.391 170.474 1.00 9.37   ? 67   LEU A CA  1 
ATOM 386  C C   . LEU A 1 67   ? 159.853 191.270 170.364 1.00 12.39  ? 67   LEU A C   1 
ATOM 387  O O   . LEU A 1 67   ? 159.520 190.162 169.930 1.00 17.00  ? 67   LEU A O   1 
ATOM 388  C CB  . LEU A 1 67   ? 157.828 192.070 171.580 1.00 16.15  ? 67   LEU A CB  1 
ATOM 389  C CG  . LEU A 1 67   ? 158.457 191.964 172.970 1.00 14.52  ? 67   LEU A CG  1 
ATOM 390  C CD1 . LEU A 1 67   ? 158.908 193.323 173.459 1.00 15.52  ? 67   LEU A CD1 1 
ATOM 391  C CD2 . LEU A 1 67   ? 157.494 191.326 173.953 1.00 12.27  ? 67   LEU A CD2 1 
ATOM 392  N N   . LEU A 1 68   ? 161.088 191.558 170.760 1.00 13.22  ? 68   LEU A N   1 
ATOM 393  C CA  . LEU A 1 68   ? 162.128 190.541 170.884 1.00 11.07  ? 68   LEU A CA  1 
ATOM 394  C C   . LEU A 1 68   ? 162.319 190.308 172.379 1.00 16.32  ? 68   LEU A C   1 
ATOM 395  O O   . LEU A 1 68   ? 163.060 191.026 173.051 1.00 16.00  ? 68   LEU A O   1 
ATOM 396  C CB  . LEU A 1 68   ? 163.414 190.976 170.191 1.00 8.20   ? 68   LEU A CB  1 
ATOM 397  C CG  . LEU A 1 68   ? 164.688 190.195 170.509 1.00 7.75   ? 68   LEU A CG  1 
ATOM 398  C CD1 . LEU A 1 68   ? 164.711 188.894 169.735 1.00 7.77   ? 68   LEU A CD1 1 
ATOM 399  C CD2 . LEU A 1 68   ? 165.901 191.026 170.166 1.00 9.59   ? 68   LEU A CD2 1 
ATOM 400  N N   . SER A 1 69   ? 161.626 189.299 172.901 1.00 14.02  ? 69   SER A N   1 
ATOM 401  C CA  . SER A 1 69   ? 161.658 189.019 174.327 1.00 5.15   ? 69   SER A CA  1 
ATOM 402  C C   . SER A 1 69   ? 163.064 188.621 174.765 1.00 8.39   ? 69   SER A C   1 
ATOM 403  O O   . SER A 1 69   ? 163.920 188.261 173.953 1.00 14.91  ? 69   SER A O   1 
ATOM 404  C CB  . SER A 1 69   ? 160.662 187.915 174.677 1.00 15.99  ? 69   SER A CB  1 
ATOM 405  O OG  . SER A 1 69   ? 160.877 186.763 173.883 1.00 15.57  ? 69   SER A OG  1 
ATOM 406  N N   . TRP A 1 70   ? 163.299 188.700 176.077 1.00 11.27  ? 70   TRP A N   1 
ATOM 407  C CA  . TRP A 1 70   ? 164.635 188.444 176.603 1.00 4.75   ? 70   TRP A CA  1 
ATOM 408  C C   . TRP A 1 70   ? 165.073 187.009 176.343 1.00 6.66   ? 70   TRP A C   1 
ATOM 409  O O   . TRP A 1 70   ? 166.227 186.766 175.972 1.00 12.13  ? 70   TRP A O   1 
ATOM 410  C CB  . TRP A 1 70   ? 164.686 188.766 178.095 1.00 5.77   ? 70   TRP A CB  1 
ATOM 411  C CG  . TRP A 1 70   ? 164.193 190.138 178.415 1.00 11.12  ? 70   TRP A CG  1 
ATOM 412  C CD1 . TRP A 1 70   ? 163.099 190.463 179.160 1.00 9.41   ? 70   TRP A CD1 1 
ATOM 413  C CD2 . TRP A 1 70   ? 164.765 191.377 177.980 1.00 9.46   ? 70   TRP A CD2 1 
ATOM 414  N NE1 . TRP A 1 70   ? 162.962 191.827 179.228 1.00 13.25  ? 70   TRP A NE1 1 
ATOM 415  C CE2 . TRP A 1 70   ? 163.972 192.411 178.510 1.00 11.16  ? 70   TRP A CE2 1 
ATOM 416  C CE3 . TRP A 1 70   ? 165.874 191.711 177.196 1.00 6.14   ? 70   TRP A CE3 1 
ATOM 417  C CZ2 . TRP A 1 70   ? 164.252 193.755 178.282 1.00 11.27  ? 70   TRP A CZ2 1 
ATOM 418  C CZ3 . TRP A 1 70   ? 166.150 193.045 176.974 1.00 6.05   ? 70   TRP A CZ3 1 
ATOM 419  C CH2 . TRP A 1 70   ? 165.342 194.050 177.514 1.00 9.30   ? 70   TRP A CH2 1 
ATOM 420  N N   . GLU A 1 71   ? 164.171 186.043 176.527 1.00 8.31   ? 71   GLU A N   1 
ATOM 421  C CA  . GLU A 1 71   ? 164.512 184.664 176.193 1.00 7.55   ? 71   GLU A CA  1 
ATOM 422  C C   . GLU A 1 71   ? 164.796 184.522 174.702 1.00 11.47  ? 71   GLU A C   1 
ATOM 423  O O   . GLU A 1 71   ? 165.772 183.870 174.306 1.00 11.76  ? 71   GLU A O   1 
ATOM 424  C CB  . GLU A 1 71   ? 163.396 183.715 176.645 1.00 9.99   ? 71   GLU A CB  1 
ATOM 425  C CG  . GLU A 1 71   ? 161.990 184.071 176.175 1.00 14.13  ? 71   GLU A CG  1 
ATOM 426  C CD  . GLU A 1 71   ? 161.188 184.828 177.221 1.00 24.14  ? 71   GLU A CD  1 
ATOM 427  O OE1 . GLU A 1 71   ? 161.798 185.543 178.044 1.00 22.03  ? 71   GLU A OE1 1 
ATOM 428  O OE2 . GLU A 1 71   ? 159.944 184.708 177.220 1.00 24.46  ? 71   GLU A OE2 1 
ATOM 429  N N   . ALA A 1 72   ? 163.974 185.157 173.863 1.00 9.90   ? 72   ALA A N   1 
ATOM 430  C CA  . ALA A 1 72   ? 164.234 185.157 172.428 1.00 4.53   ? 72   ALA A CA  1 
ATOM 431  C C   . ALA A 1 72   ? 165.531 185.884 172.106 1.00 4.14   ? 72   ALA A C   1 
ATOM 432  O O   . ALA A 1 72   ? 166.273 185.470 171.213 1.00 14.35  ? 72   ALA A O   1 
ATOM 433  C CB  . ALA A 1 72   ? 163.063 185.789 171.679 1.00 7.68   ? 72   ALA A CB  1 
ATOM 434  N N   . LEU A 1 73   ? 165.824 186.967 172.828 1.00 4.67   ? 73   LEU A N   1 
ATOM 435  C CA  . LEU A 1 73   ? 167.061 187.705 172.590 1.00 2.03   ? 73   LEU A CA  1 
ATOM 436  C C   . LEU A 1 73   ? 168.286 186.847 172.887 1.00 5.75   ? 73   LEU A C   1 
ATOM 437  O O   . LEU A 1 73   ? 169.244 186.824 172.107 1.00 13.51  ? 73   LEU A O   1 
ATOM 438  C CB  . LEU A 1 73   ? 167.083 188.980 173.431 1.00 5.87   ? 73   LEU A CB  1 
ATOM 439  C CG  . LEU A 1 73   ? 168.445 189.664 173.554 1.00 6.93   ? 73   LEU A CG  1 
ATOM 440  C CD1 . LEU A 1 73   ? 168.750 190.490 172.318 1.00 9.44   ? 73   LEU A CD1 1 
ATOM 441  C CD2 . LEU A 1 73   ? 168.496 190.525 174.800 1.00 7.37   ? 73   LEU A CD2 1 
ATOM 442  N N   . TYR A 1 74   ? 168.276 186.139 174.019 1.00 6.23   ? 74   TYR A N   1 
ATOM 443  C CA  . TYR A 1 74   ? 169.406 185.302 174.365 1.00 7.13   ? 74   TYR A CA  1 
ATOM 444  C C   . TYR A 1 74   ? 169.479 184.141 173.418 1.00 6.38   ? 74   TYR A C   1 
ATOM 445  O O   . TYR A 1 74   ? 170.511 183.924 172.872 1.00 12.89  ? 74   TYR A O   1 
ATOM 446  C CB  . TYR A 1 74   ? 169.318 184.831 175.810 1.00 7.48   ? 74   TYR A CB  1 
ATOM 447  C CG  . TYR A 1 74   ? 169.548 185.939 176.812 1.00 3.77   ? 74   TYR A CG  1 
ATOM 448  C CD1 . TYR A 1 74   ? 170.725 186.671 176.809 1.00 5.68   ? 74   TYR A CD1 1 
ATOM 449  C CD2 . TYR A 1 74   ? 168.582 186.259 177.755 1.00 4.52   ? 74   TYR A CD2 1 
ATOM 450  C CE1 . TYR A 1 74   ? 170.935 187.686 177.718 1.00 0.03   ? 74   TYR A CE1 1 
ATOM 451  C CE2 . TYR A 1 74   ? 168.782 187.274 178.666 1.00 5.56   ? 74   TYR A CE2 1 
ATOM 452  C CZ  . TYR A 1 74   ? 169.960 187.984 178.643 1.00 6.05   ? 74   TYR A CZ  1 
ATOM 453  O OH  . TYR A 1 74   ? 170.166 188.996 179.551 1.00 9.43   ? 74   TYR A OH  1 
ATOM 454  N N   . ARG A 1 75   ? 168.388 183.499 173.058 1.00 8.25   ? 75   ARG A N   1 
ATOM 455  C CA  . ARG A 1 75   ? 168.436 182.424 172.063 1.00 6.45   ? 75   ARG A CA  1 
ATOM 456  C C   . ARG A 1 75   ? 168.984 182.911 170.726 1.00 9.49   ? 75   ARG A C   1 
ATOM 457  O O   . ARG A 1 75   ? 169.722 182.189 170.046 1.00 13.09  ? 75   ARG A O   1 
ATOM 458  C CB  . ARG A 1 75   ? 167.024 181.859 171.899 1.00 10.75  ? 75   ARG A CB  1 
ATOM 459  C CG  . ARG A 1 75   ? 166.944 180.475 171.294 1.00 11.67  ? 75   ARG A CG  1 
ATOM 460  C CD  . ARG A 1 75   ? 165.632 180.309 170.554 1.00 7.49   ? 75   ARG A CD  1 
ATOM 461  N NE  . ARG A 1 75   ? 164.556 181.035 171.218 1.00 9.92   ? 75   ARG A NE  1 
ATOM 462  C CZ  . ARG A 1 75   ? 163.502 181.549 170.598 1.00 16.87  ? 75   ARG A CZ  1 
ATOM 463  N NH1 . ARG A 1 75   ? 163.343 181.429 169.290 1.00 12.81  ? 75   ARG A NH1 1 
ATOM 464  N NH2 . ARG A 1 75   ? 162.586 182.200 171.308 1.00 10.62  ? 75   ARG A NH2 1 
ATOM 465  N N   . LEU A 1 76   ? 168.633 184.139 170.337 1.00 7.80   ? 76   LEU A N   1 
ATOM 466  C CA  . LEU A 1 76   ? 169.144 184.724 169.103 1.00 7.54   ? 76   LEU A CA  1 
ATOM 467  C C   . LEU A 1 76   ? 170.638 184.999 169.195 1.00 5.61   ? 76   LEU A C   1 
ATOM 468  O O   . LEU A 1 76   ? 171.376 184.777 168.228 1.00 13.86  ? 76   LEU A O   1 
ATOM 469  C CB  . LEU A 1 76   ? 168.373 186.008 168.794 1.00 5.58   ? 76   LEU A CB  1 
ATOM 470  C CG  . LEU A 1 76   ? 168.894 186.940 167.704 1.00 3.92   ? 76   LEU A CG  1 
ATOM 471  C CD1 . LEU A 1 76   ? 168.895 186.231 166.367 1.00 9.49   ? 76   LEU A CD1 1 
ATOM 472  C CD2 . LEU A 1 76   ? 168.051 188.201 167.647 1.00 0.00   ? 76   LEU A CD2 1 
ATOM 473  N N   . LEU A 1 77   ? 171.099 185.494 170.345 1.00 0.20   ? 77   LEU A N   1 
ATOM 474  C CA  . LEU A 1 77   ? 172.525 185.742 170.524 1.00 2.87   ? 77   LEU A CA  1 
ATOM 475  C C   . LEU A 1 77   ? 173.327 184.455 170.437 1.00 4.15   ? 77   LEU A C   1 
ATOM 476  O O   . LEU A 1 77   ? 174.438 184.453 169.896 1.00 11.41  ? 77   LEU A O   1 
ATOM 477  C CB  . LEU A 1 77   ? 172.785 186.436 171.861 1.00 6.98   ? 77   LEU A CB  1 
ATOM 478  C CG  . LEU A 1 77   ? 172.232 187.850 172.036 1.00 10.32  ? 77   LEU A CG  1 
ATOM 479  C CD1 . LEU A 1 77   ? 172.229 188.232 173.504 1.00 5.58   ? 77   LEU A CD1 1 
ATOM 480  C CD2 . LEU A 1 77   ? 173.032 188.848 171.220 1.00 9.78   ? 77   LEU A CD2 1 
ATOM 481  N N   . GLU A 1 78   ? 172.790 183.355 170.964 1.00 5.10   ? 78   GLU A N   1 
ATOM 482  C CA  . GLU A 1 78   ? 173.478 182.078 170.825 1.00 6.59   ? 78   GLU A CA  1 
ATOM 483  C C   . GLU A 1 78   ? 173.246 181.412 169.474 1.00 9.98   ? 78   GLU A C   1 
ATOM 484  O O   . GLU A 1 78   ? 173.900 180.407 169.177 1.00 13.25  ? 78   GLU A O   1 
ATOM 485  C CB  . GLU A 1 78   ? 173.067 181.123 171.951 1.00 6.22   ? 78   GLU A CB  1 
ATOM 486  C CG  . GLU A 1 78   ? 173.545 181.579 173.323 1.00 13.87  ? 78   GLU A CG  1 
ATOM 487  C CD  . GLU A 1 78   ? 172.669 182.565 173.972 1.00 21.20  ? 78   GLU A CD  1 
ATOM 488  O OE1 . GLU A 1 78   ? 171.766 182.745 173.364 1.00 26.01  ? 78   GLU A OE1 1 
ATOM 489  O OE2 . GLU A 1 78   ? 172.918 183.103 175.047 1.00 14.48  ? 78   GLU A OE2 1 
ATOM 490  N N   . ASP A 1 79   ? 172.343 181.941 168.651 1.00 16.39  ? 79   ASP A N   1 
ATOM 491  C CA  . ASP A 1 79   ? 172.092 181.375 167.332 1.00 11.00  ? 79   ASP A CA  1 
ATOM 492  C C   . ASP A 1 79   ? 173.186 181.806 166.363 1.00 10.57  ? 79   ASP A C   1 
ATOM 493  O O   . ASP A 1 79   ? 173.459 183.000 166.210 1.00 13.57  ? 79   ASP A O   1 
ATOM 494  C CB  . ASP A 1 79   ? 170.720 181.813 166.819 1.00 7.18   ? 79   ASP A CB  1 
ATOM 495  C CG  . ASP A 1 79   ? 170.299 181.070 165.566 1.00 15.09  ? 79   ASP A CG  1 
ATOM 496  O OD1 . ASP A 1 79   ? 171.043 180.173 165.118 1.00 15.02  ? 79   ASP A OD1 1 
ATOM 497  O OD2 . ASP A 1 79   ? 169.216 181.378 165.031 1.00 20.27  ? 79   ASP A OD2 1 
ATOM 498  N N   . GLU A 1 80   ? 173.808 180.827 165.706 1.00 13.19  ? 80   GLU A N   1 
ATOM 499  C CA  . GLU A 1 80   ? 174.916 181.091 164.797 1.00 11.31  ? 80   GLU A CA  1 
ATOM 500  C C   . GLU A 1 80   ? 174.460 181.485 163.398 1.00 14.24  ? 80   GLU A C   1 
ATOM 501  O O   . GLU A 1 80   ? 175.184 182.212 162.708 1.00 16.97  ? 80   GLU A O   1 
ATOM 502  C CB  . GLU A 1 80   ? 175.828 179.860 164.718 1.00 13.48  ? 80   GLU A CB  1 
ATOM 503  C CG  . GLU A 1 80   ? 177.055 180.023 163.831 1.00 16.51  ? 80   GLU A CG  1 
ATOM 504  C CD  . GLU A 1 80   ? 178.025 181.065 164.355 1.00 23.93  ? 80   GLU A CD  1 
ATOM 505  O OE1 . GLU A 1 80   ? 178.036 181.310 165.580 1.00 20.23  ? 80   GLU A OE1 1 
ATOM 506  O OE2 . GLU A 1 80   ? 178.778 181.640 163.541 1.00 23.18  ? 80   GLU A OE2 1 
ATOM 507  N N   . GLU A 1 81   ? 173.279 181.037 162.969 1.00 14.24  ? 81   GLU A N   1 
ATOM 508  C CA  . GLU A 1 81   ? 172.771 181.405 161.653 1.00 3.88   ? 81   GLU A CA  1 
ATOM 509  C C   . GLU A 1 81   ? 172.482 182.895 161.537 1.00 4.66   ? 81   GLU A C   1 
ATOM 510  O O   . GLU A 1 81   ? 172.396 183.411 160.418 1.00 10.76  ? 81   GLU A O   1 
ATOM 511  C CB  . GLU A 1 81   ? 171.508 180.606 161.334 1.00 7.98   ? 81   GLU A CB  1 
ATOM 512  C CG  . GLU A 1 81   ? 171.696 179.102 161.397 1.00 13.03  ? 81   GLU A CG  1 
ATOM 513  C CD  . GLU A 1 81   ? 170.381 178.351 161.399 1.00 19.02  ? 81   GLU A CD  1 
ATOM 514  O OE1 . GLU A 1 81   ? 170.408 177.102 161.404 1.00 22.84  ? 81   GLU A OE1 1 
ATOM 515  O OE2 . GLU A 1 81   ? 169.319 179.008 161.396 1.00 21.87  ? 81   GLU A OE2 1 
ATOM 516  N N   . HIS A 1 82   ? 172.327 183.594 162.661 1.00 9.11   ? 82   HIS A N   1 
ATOM 517  C CA  . HIS A 1 82   ? 172.082 185.029 162.670 1.00 4.18   ? 82   HIS A CA  1 
ATOM 518  C C   . HIS A 1 82   ? 173.249 185.817 163.248 1.00 4.91   ? 82   HIS A C   1 
ATOM 519  O O   . HIS A 1 82   ? 173.087 186.999 163.565 1.00 9.93   ? 82   HIS A O   1 
ATOM 520  C CB  . HIS A 1 82   ? 170.809 185.343 163.454 1.00 3.12   ? 82   HIS A CB  1 
ATOM 521  C CG  . HIS A 1 82   ? 169.564 184.788 162.838 1.00 3.59   ? 82   HIS A CG  1 
ATOM 522  N ND1 . HIS A 1 82   ? 168.873 185.440 161.840 1.00 8.27   ? 82   HIS A ND1 1 
ATOM 523  C CD2 . HIS A 1 82   ? 168.885 183.642 163.079 1.00 5.55   ? 82   HIS A CD2 1 
ATOM 524  C CE1 . HIS A 1 82   ? 167.822 184.720 161.494 1.00 7.96   ? 82   HIS A CE1 1 
ATOM 525  N NE2 . HIS A 1 82   ? 167.806 183.625 162.231 1.00 14.50  ? 82   HIS A NE2 1 
ATOM 526  N N   . ALA A 1 83   ? 174.420 185.192 163.394 1.00 6.62   ? 83   ALA A N   1 
ATOM 527  C CA  . ALA A 1 83   ? 175.557 185.876 164.002 1.00 3.45   ? 83   ALA A CA  1 
ATOM 528  C C   . ALA A 1 83   ? 175.995 187.074 163.170 1.00 4.35   ? 83   ALA A C   1 
ATOM 529  O O   . ALA A 1 83   ? 176.320 188.134 163.718 1.00 5.09   ? 83   ALA A O   1 
ATOM 530  C CB  . ALA A 1 83   ? 176.716 184.899 164.190 1.00 7.94   ? 83   ALA A CB  1 
ATOM 531  N N   . SER A 1 84   ? 176.016 186.925 161.844 1.00 8.58   ? 84   SER A N   1 
ATOM 532  C CA  . SER A 1 84   ? 176.404 188.030 160.977 1.00 3.11   ? 84   SER A CA  1 
ATOM 533  C C   . SER A 1 84   ? 175.336 189.112 160.906 1.00 7.58   ? 84   SER A C   1 
ATOM 534  O O   . SER A 1 84   ? 175.644 190.243 160.516 1.00 15.20  ? 84   SER A O   1 
ATOM 535  C CB  . SER A 1 84   ? 176.709 187.510 159.572 1.00 5.10   ? 84   SER A CB  1 
ATOM 536  O OG  . SER A 1 84   ? 175.598 186.813 159.037 1.00 12.52  ? 84   SER A OG  1 
ATOM 537  N N   . SER A 1 85   ? 174.096 188.793 161.271 1.00 8.54   ? 85   SER A N   1 
ATOM 538  C CA  . SER A 1 85   ? 173.000 189.749 161.219 1.00 5.42   ? 85   SER A CA  1 
ATOM 539  C C   . SER A 1 85   ? 172.833 190.546 162.505 1.00 6.52   ? 85   SER A C   1 
ATOM 540  O O   . SER A 1 85   ? 172.103 191.542 162.504 1.00 9.11   ? 85   SER A O   1 
ATOM 541  C CB  . SER A 1 85   ? 171.689 189.023 160.907 1.00 4.75   ? 85   SER A CB  1 
ATOM 542  O OG  . SER A 1 85   ? 171.726 188.431 159.622 1.00 11.57  ? 85   SER A OG  1 
ATOM 543  N N   . LEU A 1 86   ? 173.478 190.133 163.594 1.00 6.61   ? 86   LEU A N   1 
ATOM 544  C CA  . LEU A 1 86   ? 173.291 190.830 164.872 1.00 5.73   ? 86   LEU A CA  1 
ATOM 545  C C   . LEU A 1 86   ? 173.700 192.300 164.853 1.00 9.27   ? 86   LEU A C   1 
ATOM 546  O O   . LEU A 1 86   ? 172.971 193.119 165.456 1.00 12.26  ? 86   LEU A O   1 
ATOM 547  C CB  . LEU A 1 86   ? 174.018 190.052 165.984 1.00 4.08   ? 86   LEU A CB  1 
ATOM 548  C CG  . LEU A 1 86   ? 173.424 188.705 166.402 1.00 4.82   ? 86   LEU A CG  1 
ATOM 549  C CD1 . LEU A 1 86   ? 174.421 187.930 167.246 1.00 4.56   ? 86   LEU A CD1 1 
ATOM 550  C CD2 . LEU A 1 86   ? 172.112 188.882 167.143 1.00 7.59   ? 86   LEU A CD2 1 
ATOM 551  N N   . PRO A 1 87   ? 174.799 192.711 164.227 1.00 11.59  ? 87   PRO A N   1 
ATOM 552  C CA  . PRO A 1 87   ? 175.208 194.132 164.213 1.00 10.82  ? 87   PRO A CA  1 
ATOM 553  C C   . PRO A 1 87   ? 174.156 195.067 163.669 1.00 9.78   ? 87   PRO A C   1 
ATOM 554  O O   . PRO A 1 87   ? 174.325 196.280 163.757 1.00 9.53   ? 87   PRO A O   1 
ATOM 555  C CB  . PRO A 1 87   ? 176.452 194.107 163.301 1.00 2.69   ? 87   PRO A CB  1 
ATOM 556  C CG  . PRO A 1 87   ? 176.807 192.665 163.085 1.00 6.76   ? 87   PRO A CG  1 
ATOM 557  C CD  . PRO A 1 87   ? 175.923 191.794 163.865 1.00 8.41   ? 87   PRO A CD  1 
ATOM 558  N N   . LEU A 1 88   ? 173.073 194.526 163.107 1.00 8.62   ? 88   LEU A N   1 
ATOM 559  C CA  . LEU A 1 88   ? 172.041 195.383 162.533 1.00 5.91   ? 88   LEU A CA  1 
ATOM 560  C C   . LEU A 1 88   ? 171.310 196.192 163.597 1.00 8.03   ? 88   LEU A C   1 
ATOM 561  O O   . LEU A 1 88   ? 170.919 197.336 163.341 1.00 12.39  ? 88   LEU A O   1 
ATOM 562  C CB  . LEU A 1 88   ? 171.046 194.546 161.731 1.00 6.43   ? 88   LEU A CB  1 
ATOM 563  C CG  . LEU A 1 88   ? 171.463 194.198 160.301 1.00 2.41   ? 88   LEU A CG  1 
ATOM 564  C CD1 . LEU A 1 88   ? 170.594 193.087 159.743 1.00 0.00   ? 88   LEU A CD1 1 
ATOM 565  C CD2 . LEU A 1 88   ? 171.400 195.426 159.414 1.00 5.93   ? 88   LEU A CD2 1 
ATOM 566  N N   . ILE A 1 89   ? 171.109 195.622 164.785 1.00 10.93  ? 89   ILE A N   1 
ATOM 567  C CA  . ILE A 1 89   ? 170.364 196.298 165.842 1.00 12.55  ? 89   ILE A CA  1 
ATOM 568  C C   . ILE A 1 89   ? 171.312 196.775 166.934 1.00 17.38  ? 89   ILE A C   1 
ATOM 569  O O   . ILE A 1 89   ? 171.030 197.757 167.629 1.00 19.54  ? 89   ILE A O   1 
ATOM 570  C CB  . ILE A 1 89   ? 169.263 195.385 166.412 1.00 8.84   ? 89   ILE A CB  1 
ATOM 571  C CG1 . ILE A 1 89   ? 169.857 194.131 167.048 1.00 2.44   ? 89   ILE A CG1 1 
ATOM 572  C CG2 . ILE A 1 89   ? 168.298 194.982 165.331 1.00 9.31   ? 89   ILE A CG2 1 
ATOM 573  C CD1 . ILE A 1 89   ? 168.837 193.328 167.814 1.00 9.64   ? 89   ILE A CD1 1 
ATOM 574  N N   . GLY A 1 90   ? 172.443 196.093 167.088 1.00 18.52  ? 90   GLY A N   1 
ATOM 575  C CA  . GLY A 1 90   ? 173.437 196.502 168.059 1.00 18.87  ? 90   GLY A CA  1 
ATOM 576  C C   . GLY A 1 90   ? 173.008 196.315 169.499 1.00 22.60  ? 90   GLY A C   1 
ATOM 577  O O   . GLY A 1 90   ? 172.903 197.288 170.253 1.00 20.55  ? 90   GLY A O   1 
ATOM 578  N N   . VAL A 1 91   ? 172.750 195.070 169.889 1.00 21.33  ? 91   VAL A N   1 
ATOM 579  C CA  . VAL A 1 91   ? 172.447 194.776 171.293 1.00 17.76  ? 91   VAL A CA  1 
ATOM 580  C C   . VAL A 1 91   ? 173.655 195.141 172.143 1.00 22.27  ? 91   VAL A C   1 
ATOM 581  O O   . VAL A 1 91   ? 174.801 194.864 171.735 1.00 27.31  ? 91   VAL A O   1 
ATOM 582  C CB  . VAL A 1 91   ? 172.077 193.292 171.464 1.00 15.84  ? 91   VAL A CB  1 
ATOM 583  C CG1 . VAL A 1 91   ? 171.737 192.971 172.910 1.00 19.40  ? 91   VAL A CG1 1 
ATOM 584  C CG2 . VAL A 1 91   ? 170.918 192.935 170.565 1.00 17.51  ? 91   VAL A CG2 1 
ATOM 585  N N   . PRO A 1 92   ? 173.479 195.775 173.303 1.00 15.18  ? 92   PRO A N   1 
ATOM 586  C CA  . PRO A 1 92   ? 174.640 196.129 174.128 1.00 16.71  ? 92   PRO A CA  1 
ATOM 587  C C   . PRO A 1 92   ? 175.414 194.892 174.555 1.00 14.26  ? 92   PRO A C   1 
ATOM 588  O O   . PRO A 1 92   ? 174.847 193.820 174.773 1.00 12.78  ? 92   PRO A O   1 
ATOM 589  C CB  . PRO A 1 92   ? 174.023 196.849 175.333 1.00 17.95  ? 92   PRO A CB  1 
ATOM 590  C CG  . PRO A 1 92   ? 172.634 197.178 174.950 1.00 14.78  ? 92   PRO A CG  1 
ATOM 591  C CD  . PRO A 1 92   ? 172.207 196.223 173.895 1.00 16.02  ? 92   PRO A CD  1 
ATOM 592  N N   . ASP A 1 93   ? 176.729 195.054 174.654 1.00 17.64  ? 93   ASP A N   1 
ATOM 593  C CA  . ASP A 1 93   ? 177.594 193.947 175.032 1.00 21.95  ? 93   ASP A CA  1 
ATOM 594  C C   . ASP A 1 93   ? 177.282 193.490 176.449 1.00 23.14  ? 93   ASP A C   1 
ATOM 595  O O   . ASP A 1 93   ? 176.990 194.301 177.332 1.00 24.32  ? 93   ASP A O   1 
ATOM 596  C CB  . ASP A 1 93   ? 179.061 194.356 174.921 1.00 22.96  ? 93   ASP A CB  1 
ATOM 597  C CG  . ASP A 1 93   ? 179.501 194.566 173.487 1.00 31.99  ? 93   ASP A CG  1 
ATOM 598  O OD1 . ASP A 1 93   ? 178.934 193.910 172.588 1.00 29.05  ? 93   ASP A OD1 1 
ATOM 599  O OD2 . ASP A 1 93   ? 180.413 195.388 173.257 1.00 35.24  ? 93   ASP A OD2 1 
ATOM 600  N N   . ILE A 1 94   ? 177.341 192.177 176.662 1.00 19.52  ? 94   ILE A N   1 
ATOM 601  C CA  . ILE A 1 94   ? 177.039 191.610 177.970 1.00 12.29  ? 94   ILE A CA  1 
ATOM 602  C C   . ILE A 1 94   ? 178.111 192.051 178.957 1.00 15.80  ? 94   ILE A C   1 
ATOM 603  O O   . ILE A 1 94   ? 179.310 191.884 178.709 1.00 20.44  ? 94   ILE A O   1 
ATOM 604  C CB  . ILE A 1 94   ? 176.945 190.081 177.895 1.00 10.29  ? 94   ILE A CB  1 
ATOM 605  C CG1 . ILE A 1 94   ? 175.642 189.662 177.216 1.00 9.57   ? 94   ILE A CG1 1 
ATOM 606  C CG2 . ILE A 1 94   ? 177.044 189.469 179.282 1.00 13.02  ? 94   ILE A CG2 1 
ATOM 607  C CD1 . ILE A 1 94   ? 175.410 188.171 177.214 1.00 21.37  ? 94   ILE A CD1 1 
ATOM 608  N N   . LEU A 1 95   ? 177.682 192.626 180.073 1.00 11.64  ? 95   LEU A N   1 
ATOM 609  C CA  . LEU A 1 95   ? 178.609 193.025 181.122 1.00 12.58  ? 95   LEU A CA  1 
ATOM 610  C C   . LEU A 1 95   ? 178.872 191.842 182.044 1.00 18.30  ? 95   LEU A C   1 
ATOM 611  O O   . LEU A 1 95   ? 177.924 191.314 182.637 1.00 26.02  ? 95   LEU A O   1 
ATOM 612  C CB  . LEU A 1 95   ? 178.043 194.196 181.914 1.00 16.59  ? 95   LEU A CB  1 
ATOM 613  C CG  . LEU A 1 95   ? 178.905 194.766 183.041 1.00 18.09  ? 95   LEU A CG  1 
ATOM 614  C CD1 . LEU A 1 95   ? 180.149 195.431 182.481 1.00 20.00  ? 95   LEU A CD1 1 
ATOM 615  C CD2 . LEU A 1 95   ? 178.102 195.750 183.876 1.00 16.68  ? 95   LEU A CD2 1 
ATOM 616  N N   . PRO A 1 96   ? 180.121 191.384 182.182 1.00 19.05  ? 96   PRO A N   1 
ATOM 617  C CA  . PRO A 1 96   ? 180.394 190.287 183.118 1.00 18.53  ? 96   PRO A CA  1 
ATOM 618  C C   . PRO A 1 96   ? 180.035 190.675 184.541 1.00 20.07  ? 96   PRO A C   1 
ATOM 619  O O   . PRO A 1 96   ? 180.695 191.525 185.145 1.00 23.36  ? 96   PRO A O   1 
ATOM 620  C CB  . PRO A 1 96   ? 181.903 190.055 182.972 1.00 20.69  ? 96   PRO A CB  1 
ATOM 621  C CG  . PRO A 1 96   ? 182.281 190.639 181.664 1.00 18.46  ? 96   PRO A CG  1 
ATOM 622  C CD  . PRO A 1 96   ? 181.208 191.584 181.209 1.00 21.46  ? 96   PRO A CD  1 
ATOM 623  N N   . LEU A 1 97   ? 178.992 190.055 185.085 1.00 17.59  ? 97   LEU A N   1 
ATOM 624  C CA  . LEU A 1 97   ? 178.479 190.405 186.400 1.00 17.28  ? 97   LEU A CA  1 
ATOM 625  C C   . LEU A 1 97   ? 178.288 189.152 187.236 1.00 19.72  ? 97   LEU A C   1 
ATOM 626  O O   . LEU A 1 97   ? 177.828 188.122 186.736 1.00 19.33  ? 97   LEU A O   1 
ATOM 627  C CB  . LEU A 1 97   ? 177.153 191.162 186.299 1.00 16.75  ? 97   LEU A CB  1 
ATOM 628  C CG  . LEU A 1 97   ? 177.269 192.677 186.174 1.00 14.08  ? 97   LEU A CG  1 
ATOM 629  C CD1 . LEU A 1 97   ? 175.911 193.323 186.359 1.00 13.49  ? 97   LEU A CD1 1 
ATOM 630  C CD2 . LEU A 1 97   ? 178.266 193.207 187.187 1.00 20.08  ? 97   LEU A CD2 1 
ATOM 631  N N   . ARG A 1 98   ? 178.646 189.252 188.511 1.00 18.33  ? 98   ARG A N   1 
ATOM 632  C CA  . ARG A 1 98   ? 178.438 188.188 189.479 1.00 20.19  ? 98   ARG A CA  1 
ATOM 633  C C   . ARG A 1 98   ? 177.571 188.722 190.608 1.00 21.10  ? 98   ARG A C   1 
ATOM 634  O O   . ARG A 1 98   ? 177.915 189.725 191.240 1.00 23.47  ? 98   ARG A O   1 
ATOM 635  C CB  . ARG A 1 98   ? 179.768 187.672 190.026 1.00 21.85  ? 98   ARG A CB  1 
ATOM 636  C CG  . ARG A 1 98   ? 180.668 187.015 188.983 1.00 23.83  ? 98   ARG A CG  1 
ATOM 637  C CD  . ARG A 1 98   ? 180.086 185.685 188.500 1.00 21.36  ? 98   ARG A CD  1 
ATOM 638  N NE  . ARG A 1 98   ? 180.962 184.954 187.586 1.00 22.42  ? 98   ARG A NE  1 
ATOM 639  C CZ  . ARG A 1 98   ? 180.957 185.048 186.261 1.00 23.39  ? 98   ARG A CZ  1 
ATOM 640  N NH1 . ARG A 1 98   ? 180.068 185.786 185.618 1.00 22.46  ? 98   ARG A NH1 1 
ATOM 641  N NH2 . ARG A 1 98   ? 181.854 184.361 185.562 1.00 26.65  ? 98   ARG A NH2 1 
ATOM 642  N N   . ALA A 1 99   ? 176.449 188.058 190.850 1.00 17.16  ? 99   ALA A N   1 
ATOM 643  C CA  . ALA A 1 99   ? 175.559 188.432 191.933 1.00 11.77  ? 99   ALA A CA  1 
ATOM 644  C C   . ALA A 1 99   ? 175.934 187.680 193.199 1.00 15.85  ? 99   ALA A C   1 
ATOM 645  O O   . ALA A 1 99   ? 176.438 186.557 193.150 1.00 21.28  ? 99   ALA A O   1 
ATOM 646  C CB  . ALA A 1 99   ? 174.105 188.135 191.566 1.00 12.96  ? 99   ALA A CB  1 
ATOM 647  N N   . SER A 1 100  ? 175.701 188.315 194.340 1.00 10.72  ? 100  SER A N   1 
ATOM 648  C CA  . SER A 1 100  ? 175.768 187.628 195.623 1.00 16.61  ? 100  SER A CA  1 
ATOM 649  C C   . SER A 1 100  ? 174.380 187.710 196.241 1.00 16.54  ? 100  SER A C   1 
ATOM 650  O O   . SER A 1 100  ? 173.830 188.804 196.406 1.00 17.91  ? 100  SER A O   1 
ATOM 651  C CB  . SER A 1 100  ? 176.834 188.227 196.536 1.00 16.87  ? 100  SER A CB  1 
ATOM 652  O OG  . SER A 1 100  ? 176.351 189.376 197.201 1.00 16.37  ? 100  SER A OG  1 
ATOM 653  N N   . LEU A 1 101  ? 173.811 186.552 196.550 1.00 14.77  ? 101  LEU A N   1 
ATOM 654  C CA  . LEU A 1 101  ? 172.462 186.485 197.081 1.00 10.32  ? 101  LEU A CA  1 
ATOM 655  C C   . LEU A 1 101  ? 172.477 186.726 198.583 1.00 13.24  ? 101  LEU A C   1 
ATOM 656  O O   . LEU A 1 101  ? 173.396 186.299 199.287 1.00 22.76  ? 101  LEU A O   1 
ATOM 657  C CB  . LEU A 1 101  ? 171.844 185.123 196.769 1.00 8.50   ? 101  LEU A CB  1 
ATOM 658  C CG  . LEU A 1 101  ? 171.402 184.949 195.315 1.00 6.67   ? 101  LEU A CG  1 
ATOM 659  C CD1 . LEU A 1 101  ? 171.427 183.487 194.904 1.00 13.61  ? 101  LEU A CD1 1 
ATOM 660  C CD2 . LEU A 1 101  ? 170.027 185.546 195.099 1.00 10.36  ? 101  LEU A CD2 1 
ATOM 661  N N   . SER A 1 102  ? 171.461 187.430 199.070 1.00 8.37   ? 102  SER A N   1 
ATOM 662  C CA  . SER A 1 102  ? 171.277 187.645 200.495 1.00 11.08  ? 102  SER A CA  1 
ATOM 663  C C   . SER A 1 102  ? 169.875 187.209 200.888 1.00 19.02  ? 102  SER A C   1 
ATOM 664  O O   . SER A 1 102  ? 168.927 187.329 200.108 1.00 23.37  ? 102  SER A O   1 
ATOM 665  C CB  . SER A 1 102  ? 171.500 189.110 200.886 1.00 14.68  ? 102  SER A CB  1 
ATOM 666  O OG  . SER A 1 102  ? 172.838 189.504 200.647 1.00 21.34  ? 102  SER A OG  1 
ATOM 667  N N   . SER A 1 103  ? 169.755 186.693 202.106 1.00 18.82  ? 103  SER A N   1 
ATOM 668  C CA  . SER A 1 103  ? 168.486 186.216 202.625 1.00 19.03  ? 103  SER A CA  1 
ATOM 669  C C   . SER A 1 103  ? 168.325 186.662 204.068 1.00 22.15  ? 103  SER A C   1 
ATOM 670  O O   . SER A 1 103  ? 169.300 186.950 204.768 1.00 23.16  ? 103  SER A O   1 
ATOM 671  C CB  . SER A 1 103  ? 168.375 184.690 202.535 1.00 16.58  ? 103  SER A CB  1 
ATOM 672  O OG  . SER A 1 103  ? 169.238 184.063 203.466 1.00 22.09  ? 103  SER A OG  1 
ATOM 673  N N   . ARG A 1 104  ? 167.071 186.723 204.502 1.00 23.71  ? 104  ARG A N   1 
ATOM 674  C CA  . ARG A 1 104  ? 166.724 187.091 205.865 1.00 25.45  ? 104  ARG A CA  1 
ATOM 675  C C   . ARG A 1 104  ? 165.700 186.096 206.389 1.00 29.26  ? 104  ARG A C   1 
ATOM 676  O O   . ARG A 1 104  ? 164.689 185.836 205.728 1.00 29.17  ? 104  ARG A O   1 
ATOM 677  C CB  . ARG A 1 104  ? 166.178 188.520 205.920 1.00 25.31  ? 104  ARG A CB  1 
ATOM 678  C CG  . ARG A 1 104  ? 165.846 189.017 207.310 1.00 29.39  ? 104  ARG A CG  1 
ATOM 679  C CD  . ARG A 1 104  ? 165.327 190.441 207.246 1.00 31.55  ? 104  ARG A CD  1 
ATOM 680  N NE  . ARG A 1 104  ? 164.084 190.528 206.490 1.00 30.79  ? 104  ARG A NE  1 
ATOM 681  C CZ  . ARG A 1 104  ? 162.883 190.273 206.990 1.00 31.34  ? 104  ARG A CZ  1 
ATOM 682  N NH1 . ARG A 1 104  ? 162.722 189.918 208.255 1.00 33.01  ? 104  ARG A NH1 1 
ATOM 683  N NH2 . ARG A 1 104  ? 161.816 190.377 206.203 1.00 28.11  ? 104  ARG A NH2 1 
ATOM 684  N N   . GLY A 1 105  ? 165.963 185.544 207.568 1.00 27.05  ? 105  GLY A N   1 
ATOM 685  C CA  . GLY A 1 105  ? 165.106 184.521 208.125 1.00 20.27  ? 105  GLY A CA  1 
ATOM 686  C C   . GLY A 1 105  ? 165.427 183.142 207.575 1.00 26.30  ? 105  GLY A C   1 
ATOM 687  O O   . GLY A 1 105  ? 166.409 182.928 206.860 1.00 32.34  ? 105  GLY A O   1 
ATOM 688  N N   . ALA A 1 106  ? 164.575 182.188 207.929 1.00 23.25  ? 106  ALA A N   1 
ATOM 689  C CA  . ALA A 1 106  ? 164.695 180.808 207.477 1.00 17.17  ? 106  ALA A CA  1 
ATOM 690  C C   . ALA A 1 106  ? 163.520 180.464 206.570 1.00 16.98  ? 106  ALA A C   1 
ATOM 691  O O   . ALA A 1 106  ? 162.514 181.177 206.510 1.00 20.63  ? 106  ALA A O   1 
ATOM 692  C CB  . ALA A 1 106  ? 164.749 179.844 208.674 1.00 22.99  ? 106  ALA A CB  1 
ATOM 693  N N   . LEU A 1 107  ? 163.660 179.346 205.854 1.00 15.88  ? 107  LEU A N   1 
ATOM 694  C CA  . LEU A 1 107  ? 162.607 178.918 204.938 1.00 19.28  ? 107  LEU A CA  1 
ATOM 695  C C   . LEU A 1 107  ? 161.300 178.638 205.667 1.00 26.82  ? 107  LEU A C   1 
ATOM 696  O O   . LEU A 1 107  ? 160.221 178.780 205.081 1.00 25.33  ? 107  LEU A O   1 
ATOM 697  C CB  . LEU A 1 107  ? 163.051 177.684 204.153 1.00 14.62  ? 107  LEU A CB  1 
ATOM 698  C CG  . LEU A 1 107  ? 164.011 177.909 202.984 1.00 17.59  ? 107  LEU A CG  1 
ATOM 699  C CD1 . LEU A 1 107  ? 165.439 178.049 203.454 1.00 18.44  ? 107  LEU A CD1 1 
ATOM 700  C CD2 . LEU A 1 107  ? 163.892 176.777 201.985 1.00 20.74  ? 107  LEU A CD2 1 
ATOM 701  N N   . SER A 1 108  ? 161.371 178.235 206.938 1.00 24.46  ? 108  SER A N   1 
ATOM 702  C CA  . SER A 1 108  ? 160.153 178.055 207.719 1.00 21.44  ? 108  SER A CA  1 
ATOM 703  C C   . SER A 1 108  ? 159.447 179.382 207.966 1.00 23.55  ? 108  SER A C   1 
ATOM 704  O O   . SER A 1 108  ? 158.213 179.423 208.038 1.00 23.62  ? 108  SER A O   1 
ATOM 705  C CB  . SER A 1 108  ? 160.475 177.370 209.046 1.00 23.81  ? 108  SER A CB  1 
ATOM 706  O OG  . SER A 1 108  ? 161.504 178.056 209.737 1.00 22.11  ? 108  SER A OG  1 
ATOM 707  N N   . ASP A 1 109  ? 160.207 180.467 208.096 1.00 24.12  ? 109  ASP A N   1 
ATOM 708  C CA  . ASP A 1 109  ? 159.625 181.775 208.359 1.00 24.09  ? 109  ASP A CA  1 
ATOM 709  C C   . ASP A 1 109  ? 158.810 182.258 207.165 1.00 25.75  ? 109  ASP A C   1 
ATOM 710  O O   . ASP A 1 109  ? 159.185 182.045 206.009 1.00 23.39  ? 109  ASP A O   1 
ATOM 711  C CB  . ASP A 1 109  ? 160.723 182.786 208.682 1.00 20.45  ? 109  ASP A CB  1 
ATOM 712  C CG  . ASP A 1 109  ? 161.733 182.252 209.672 1.00 28.57  ? 109  ASP A CG  1 
ATOM 713  O OD1 . ASP A 1 109  ? 161.437 182.226 210.881 1.00 29.83  ? 109  ASP A OD1 1 
ATOM 714  O OD2 . ASP A 1 109  ? 162.817 181.872 209.253 1.00 31.12  ? 109  ASP A OD2 1 
ATOM 715  N N   . SER A 1 110  ? 157.686 182.916 207.454 1.00 29.70  ? 110  SER A N   1 
ATOM 716  C CA  . SER A 1 110  ? 156.843 183.466 206.400 1.00 31.05  ? 110  SER A CA  1 
ATOM 717  C C   . SER A 1 110  ? 157.399 184.758 205.815 1.00 30.09  ? 110  SER A C   1 
ATOM 718  O O   . SER A 1 110  ? 156.990 185.149 204.717 1.00 30.02  ? 110  SER A O   1 
ATOM 719  C CB  . SER A 1 110  ? 155.428 183.706 206.928 1.00 28.45  ? 110  SER A CB  1 
ATOM 720  O OG  . SER A 1 110  ? 154.507 183.866 205.863 1.00 31.08  ? 110  SER A OG  1 
ATOM 721  N N   . ASP A 1 111  ? 158.313 185.424 206.517 1.00 28.59  ? 111  ASP A N   1 
ATOM 722  C CA  . ASP A 1 111  ? 158.943 186.642 206.024 1.00 29.64  ? 111  ASP A CA  1 
ATOM 723  C C   . ASP A 1 111  ? 160.221 186.368 205.243 1.00 31.07  ? 111  ASP A C   1 
ATOM 724  O O   . ASP A 1 111  ? 160.919 187.316 204.870 1.00 35.79  ? 111  ASP A O   1 
ATOM 725  C CB  . ASP A 1 111  ? 159.239 187.598 207.190 1.00 29.33  ? 111  ASP A CB  1 
ATOM 726  C CG  . ASP A 1 111  ? 160.227 187.023 208.196 1.00 30.57  ? 111  ASP A CG  1 
ATOM 727  O OD1 . ASP A 1 111  ? 160.666 185.866 208.031 1.00 33.44  ? 111  ASP A OD1 1 
ATOM 728  O OD2 . ASP A 1 111  ? 160.568 187.737 209.161 1.00 31.72  ? 111  ASP A OD2 1 
ATOM 729  N N   . PHE A 1 112  ? 160.541 185.098 205.004 1.00 23.89  ? 112  PHE A N   1 
ATOM 730  C CA  . PHE A 1 112  ? 161.769 184.718 204.320 1.00 23.31  ? 112  PHE A CA  1 
ATOM 731  C C   . PHE A 1 112  ? 161.827 185.346 202.933 1.00 25.59  ? 112  PHE A C   1 
ATOM 732  O O   . PHE A 1 112  ? 160.982 185.066 202.078 1.00 24.38  ? 112  PHE A O   1 
ATOM 733  C CB  . PHE A 1 112  ? 161.841 183.195 204.225 1.00 19.38  ? 112  PHE A CB  1 
ATOM 734  C CG  . PHE A 1 112  ? 162.988 182.686 203.406 1.00 16.16  ? 112  PHE A CG  1 
ATOM 735  C CD1 . PHE A 1 112  ? 164.273 182.680 203.916 1.00 21.12  ? 112  PHE A CD1 1 
ATOM 736  C CD2 . PHE A 1 112  ? 162.781 182.221 202.119 1.00 15.62  ? 112  PHE A CD2 1 
ATOM 737  C CE1 . PHE A 1 112  ? 165.327 182.214 203.162 1.00 18.36  ? 112  PHE A CE1 1 
ATOM 738  C CE2 . PHE A 1 112  ? 163.831 181.756 201.360 1.00 15.21  ? 112  PHE A CE2 1 
ATOM 739  C CZ  . PHE A 1 112  ? 165.105 181.750 201.886 1.00 14.96  ? 112  PHE A CZ  1 
ATOM 740  N N   . ARG A 1 113  ? 162.825 186.199 202.716 1.00 24.11  ? 113  ARG A N   1 
ATOM 741  C CA  . ARG A 1 113  ? 163.026 186.870 201.440 1.00 21.21  ? 113  ARG A CA  1 
ATOM 742  C C   . ARG A 1 113  ? 164.438 186.604 200.949 1.00 20.59  ? 113  ARG A C   1 
ATOM 743  O O   . ARG A 1 113  ? 165.399 186.729 201.715 1.00 21.05  ? 113  ARG A O   1 
ATOM 744  C CB  . ARG A 1 113  ? 162.789 188.380 201.559 1.00 21.48  ? 113  ARG A CB  1 
ATOM 745  C CG  . ARG A 1 113  ? 161.338 188.773 201.764 1.00 25.42  ? 113  ARG A CG  1 
ATOM 746  C CD  . ARG A 1 113  ? 160.999 190.048 201.005 1.00 26.77  ? 113  ARG A CD  1 
ATOM 747  N NE  . ARG A 1 113  ? 161.263 189.928 199.576 1.00 28.24  ? 113  ARG A NE  1 
ATOM 748  C CZ  . ARG A 1 113  ? 162.242 190.554 198.938 1.00 29.43  ? 113  ARG A CZ  1 
ATOM 749  N NH1 . ARG A 1 113  ? 163.074 191.364 199.573 1.00 25.52  ? 113  ARG A NH1 1 
ATOM 750  N NH2 . ARG A 1 113  ? 162.391 190.364 197.630 1.00 26.53  ? 113  ARG A NH2 1 
ATOM 751  N N   . VAL A 1 114  ? 164.560 186.234 199.678 1.00 16.23  ? 114  VAL A N   1 
ATOM 752  C CA  . VAL A 1 114  ? 165.844 186.128 198.997 1.00 16.04  ? 114  VAL A CA  1 
ATOM 753  C C   . VAL A 1 114  ? 165.912 187.246 197.970 1.00 18.44  ? 114  VAL A C   1 
ATOM 754  O O   . VAL A 1 114  ? 165.024 187.370 197.118 1.00 18.96  ? 114  VAL A O   1 
ATOM 755  C CB  . VAL A 1 114  ? 166.029 184.756 198.327 1.00 15.22  ? 114  VAL A CB  1 
ATOM 756  C CG1 . VAL A 1 114  ? 167.327 184.725 197.543 1.00 10.70  ? 114  VAL A CG1 1 
ATOM 757  C CG2 . VAL A 1 114  ? 166.026 183.665 199.360 1.00 12.98  ? 114  VAL A CG2 1 
ATOM 758  N N   . TRP A 1 115  ? 166.959 188.060 198.052 1.00 12.80  ? 115  TRP A N   1 
ATOM 759  C CA  . TRP A 1 115  ? 167.112 189.199 197.165 1.00 11.67  ? 115  TRP A CA  1 
ATOM 760  C C   . TRP A 1 115  ? 168.564 189.309 196.732 1.00 10.63  ? 115  TRP A C   1 
ATOM 761  O O   . TRP A 1 115  ? 169.467 188.748 197.357 1.00 13.79  ? 115  TRP A O   1 
ATOM 762  C CB  . TRP A 1 115  ? 166.664 190.507 197.833 1.00 16.81  ? 115  TRP A CB  1 
ATOM 763  C CG  . TRP A 1 115  ? 167.627 191.024 198.859 1.00 17.64  ? 115  TRP A CG  1 
ATOM 764  C CD1 . TRP A 1 115  ? 168.650 191.904 198.654 1.00 17.13  ? 115  TRP A CD1 1 
ATOM 765  C CD2 . TRP A 1 115  ? 167.651 190.702 200.254 1.00 15.46  ? 115  TRP A CD2 1 
ATOM 766  N NE1 . TRP A 1 115  ? 169.312 192.144 199.832 1.00 16.23  ? 115  TRP A NE1 1 
ATOM 767  C CE2 . TRP A 1 115  ? 168.718 191.418 200.830 1.00 13.74  ? 115  TRP A CE2 1 
ATOM 768  C CE3 . TRP A 1 115  ? 166.874 189.876 201.071 1.00 13.93  ? 115  TRP A CE3 1 
ATOM 769  C CZ2 . TRP A 1 115  ? 169.027 191.334 202.184 1.00 15.11  ? 115  TRP A CZ2 1 
ATOM 770  C CZ3 . TRP A 1 115  ? 167.183 189.794 202.414 1.00 16.20  ? 115  TRP A CZ3 1 
ATOM 771  C CH2 . TRP A 1 115  ? 168.250 190.518 202.958 1.00 18.54  ? 115  TRP A CH2 1 
ATOM 772  N N   . ILE A 1 116  ? 168.775 190.039 195.644 1.00 16.35  ? 116  ILE A N   1 
ATOM 773  C CA  . ILE A 1 116  ? 170.104 190.389 195.168 1.00 15.23  ? 116  ILE A CA  1 
ATOM 774  C C   . ILE A 1 116  ? 170.277 191.887 195.365 1.00 27.90  ? 116  ILE A C   1 
ATOM 775  O O   . ILE A 1 116  ? 169.621 192.686 194.685 1.00 28.90  ? 116  ILE A O   1 
ATOM 776  C CB  . ILE A 1 116  ? 170.305 190.017 193.693 1.00 12.23  ? 116  ILE A CB  1 
ATOM 777  C CG1 . ILE A 1 116  ? 169.729 188.636 193.387 1.00 16.14  ? 116  ILE A CG1 1 
ATOM 778  C CG2 . ILE A 1 116  ? 171.773 190.098 193.328 1.00 13.42  ? 116  ILE A CG2 1 
ATOM 779  C CD1 . ILE A 1 116  ? 169.729 188.298 191.913 1.00 10.83  ? 116  ILE A CD1 1 
ATOM 780  N N   . ALA A 1 117  ? 171.152 192.285 196.290 1.00 26.73  ? 117  ALA A N   1 
ATOM 781  C CA  . ALA A 1 117  ? 171.677 193.646 196.302 1.00 26.68  ? 117  ALA A CA  1 
ATOM 782  C C   . ALA A 1 117  ? 173.199 193.560 196.406 1.00 26.26  ? 117  ALA A C   1 
ATOM 783  O O   . ALA A 1 117  ? 173.789 193.839 197.451 1.00 28.82  ? 117  ALA A O   1 
ATOM 784  C CB  . ALA A 1 117  ? 171.075 194.462 197.447 1.00 23.38  ? 117  ALA A CB  1 
ATOM 785  N N   . GLU A 1 118  ? 173.821 193.183 195.288 1.00 23.46  ? 118  GLU A N   1 
ATOM 786  C CA  . GLU A 1 118  ? 175.260 193.235 195.072 1.00 20.51  ? 118  GLU A CA  1 
ATOM 787  C C   . GLU A 1 118  ? 175.534 192.807 193.636 1.00 25.68  ? 118  GLU A C   1 
ATOM 788  O O   . GLU A 1 118  ? 175.026 191.772 193.195 1.00 25.45  ? 118  GLU A O   1 
ATOM 789  C CB  . GLU A 1 118  ? 176.005 192.344 196.067 1.00 17.12  ? 118  GLU A CB  1 
ATOM 790  C CG  . GLU A 1 118  ? 177.522 192.365 195.949 1.00 24.96  ? 118  GLU A CG  1 
ATOM 791  C CD  . GLU A 1 118  ? 178.138 193.713 196.274 1.00 27.88  ? 118  GLU A CD  1 
ATOM 792  O OE1 . GLU A 1 118  ? 177.527 194.494 197.034 1.00 24.07  ? 118  GLU A OE1 1 
ATOM 793  O OE2 . GLU A 1 118  ? 179.255 193.976 195.788 1.00 31.14  ? 118  GLU A OE2 1 
ATOM 794  N N   . TRP A 1 119  ? 176.325 193.577 192.896 1.00 21.48  ? 119  TRP A N   1 
ATOM 795  C CA  . TRP A 1 119  ? 176.693 193.209 191.533 1.00 19.52  ? 119  TRP A CA  1 
ATOM 796  C C   . TRP A 1 119  ? 178.146 193.589 191.318 1.00 24.91  ? 119  TRP A C   1 
ATOM 797  O O   . TRP A 1 119  ? 178.493 194.772 191.378 1.00 33.42  ? 119  TRP A O   1 
ATOM 798  C CB  . TRP A 1 119  ? 175.794 193.899 190.502 1.00 23.05  ? 119  TRP A CB  1 
ATOM 799  C CG  . TRP A 1 119  ? 174.407 193.325 190.383 1.00 19.11  ? 119  TRP A CG  1 
ATOM 800  C CD1 . TRP A 1 119  ? 173.250 193.883 190.841 1.00 18.30  ? 119  TRP A CD1 1 
ATOM 801  C CD2 . TRP A 1 119  ? 174.029 192.109 189.722 1.00 16.93  ? 119  TRP A CD2 1 
ATOM 802  N NE1 . TRP A 1 119  ? 172.180 193.083 190.527 1.00 17.15  ? 119  TRP A NE1 1 
ATOM 803  C CE2 . TRP A 1 119  ? 172.631 191.988 189.839 1.00 18.69  ? 119  TRP A CE2 1 
ATOM 804  C CE3 . TRP A 1 119  ? 174.738 191.107 189.053 1.00 15.72  ? 119  TRP A CE3 1 
ATOM 805  C CZ2 . TRP A 1 119  ? 171.928 190.906 189.313 1.00 15.97  ? 119  TRP A CZ2 1 
ATOM 806  C CZ3 . TRP A 1 119  ? 174.038 190.035 188.531 1.00 10.49  ? 119  TRP A CZ3 1 
ATOM 807  C CH2 . TRP A 1 119  ? 172.648 189.942 188.665 1.00 10.18  ? 119  TRP A CH2 1 
ATOM 808  N N   . ALA A 1 120  ? 178.990 192.594 191.067 1.00 23.61  ? 120  ALA A N   1 
ATOM 809  C CA  . ALA A 1 120  ? 180.422 192.796 190.931 1.00 22.59  ? 120  ALA A CA  1 
ATOM 810  C C   . ALA A 1 120  ? 180.904 192.294 189.577 1.00 25.55  ? 120  ALA A C   1 
ATOM 811  O O   . ALA A 1 120  ? 180.408 191.292 189.054 1.00 28.06  ? 120  ALA A O   1 
ATOM 812  C CB  . ALA A 1 120  ? 181.190 192.083 192.050 1.00 27.68  ? 120  ALA A CB  1 
ATOM 813  N N   . THR A 1 121  ? 181.875 193.008 189.013 1.00 32.51  ? 121  THR A N   1 
ATOM 814  C CA  . THR A 1 121  ? 182.522 192.557 187.790 1.00 34.53  ? 121  THR A CA  1 
ATOM 815  C C   . THR A 1 121  ? 183.293 191.268 188.053 1.00 33.10  ? 121  THR A C   1 
ATOM 816  O O   . THR A 1 121  ? 183.774 191.022 189.161 1.00 36.09  ? 121  THR A O   1 
ATOM 817  C CB  . THR A 1 121  ? 183.462 193.636 187.257 1.00 37.07  ? 121  THR A CB  1 
ATOM 818  O OG1 . THR A 1 121  ? 184.486 193.898 188.225 1.00 39.40  ? 121  THR A OG1 1 
ATOM 819  C CG2 . THR A 1 121  ? 182.693 194.920 186.990 1.00 34.77  ? 121  THR A CG2 1 
ATOM 820  N N   . PHE A 1 122  ? 183.406 190.432 187.018 1.00 33.80  ? 122  PHE A N   1 
ATOM 821  C CA  . PHE A 1 122  ? 183.989 189.106 187.216 1.00 38.03  ? 122  PHE A CA  1 
ATOM 822  C C   . PHE A 1 122  ? 185.484 189.166 187.533 1.00 42.59  ? 122  PHE A C   1 
ATOM 823  O O   . PHE A 1 122  ? 185.890 188.635 188.581 1.00 41.09  ? 122  PHE A O   1 
ATOM 824  C CB  . PHE A 1 122  ? 183.643 188.222 186.011 1.00 35.79  ? 122  PHE A CB  1 
ATOM 825  C CG  . PHE A 1 122  ? 184.102 186.796 186.140 1.00 37.54  ? 122  PHE A CG  1 
ATOM 826  C CD1 . PHE A 1 122  ? 184.267 186.206 187.382 1.00 39.15  ? 122  PHE A CD1 1 
ATOM 827  C CD2 . PHE A 1 122  ? 184.386 186.050 185.007 1.00 34.95  ? 122  PHE A CD2 1 
ATOM 828  C CE1 . PHE A 1 122  ? 184.694 184.897 187.491 1.00 39.26  ? 122  PHE A CE1 1 
ATOM 829  C CE2 . PHE A 1 122  ? 184.815 184.741 185.110 1.00 36.79  ? 122  PHE A CE2 1 
ATOM 830  C CZ  . PHE A 1 122  ? 184.966 184.164 186.354 1.00 38.87  ? 122  PHE A CZ  1 
ATOM 831  N N   . PRO A 1 123  ? 186.368 189.772 186.685 1.00 44.85  ? 123  PRO A N   1 
ATOM 832  C CA  . PRO A 1 123  ? 187.765 189.922 187.117 1.00 41.17  ? 123  PRO A CA  1 
ATOM 833  C C   . PRO A 1 123  ? 187.953 190.657 188.436 1.00 45.65  ? 123  PRO A C   1 
ATOM 834  O O   . PRO A 1 123  ? 188.490 190.099 189.400 1.00 41.91  ? 123  PRO A O   1 
ATOM 835  C CB  . PRO A 1 123  ? 188.391 190.737 185.979 1.00 41.66  ? 123  PRO A CB  1 
ATOM 836  C CG  . PRO A 1 123  ? 187.538 190.487 184.785 1.00 40.68  ? 123  PRO A CG  1 
ATOM 837  C CD  . PRO A 1 123  ? 186.326 189.708 185.215 1.00 39.37  ? 123  PRO A CD  1 
ATOM 838  N N   . ALA A 1 124  ? 187.503 191.910 188.484 1.00 46.42  ? 124  ALA A N   1 
ATOM 839  C CA  . ALA A 1 124  ? 187.919 192.827 189.537 1.00 42.98  ? 124  ALA A CA  1 
ATOM 840  C C   . ALA A 1 124  ? 187.081 192.725 190.804 1.00 42.34  ? 124  ALA A C   1 
ATOM 841  O O   . ALA A 1 124  ? 187.516 193.224 191.849 1.00 44.90  ? 124  ALA A O   1 
ATOM 842  C CB  . ALA A 1 124  ? 187.880 194.267 189.020 1.00 40.28  ? 124  ALA A CB  1 
ATOM 843  N N   . ARG A 1 125  ? 185.909 192.096 190.742 1.00 38.43  ? 125  ARG A N   1 
ATOM 844  C CA  . ARG A 1 125  ? 184.998 192.007 191.883 1.00 38.16  ? 125  ARG A CA  1 
ATOM 845  C C   . ARG A 1 125  ? 184.693 193.393 192.449 1.00 40.74  ? 125  ARG A C   1 
ATOM 846  O O   . ARG A 1 125  ? 184.707 193.618 193.661 1.00 39.41  ? 125  ARG A O   1 
ATOM 847  C CB  . ARG A 1 125  ? 185.560 191.081 192.963 1.00 40.64  ? 125  ARG A CB  1 
ATOM 848  C CG  . ARG A 1 125  ? 185.589 189.616 192.560 1.00 44.30  ? 125  ARG A CG  1 
ATOM 849  C CD  . ARG A 1 125  ? 184.352 188.885 193.053 1.00 41.82  ? 125  ARG A CD  1 
ATOM 850  N NE  . ARG A 1 125  ? 183.922 187.849 192.122 1.00 43.08  ? 125  ARG A NE  1 
ATOM 851  C CZ  . ARG A 1 125  ? 184.327 186.587 192.165 1.00 43.61  ? 125  ARG A CZ  1 
ATOM 852  N NH1 . ARG A 1 125  ? 185.181 186.166 193.084 1.00 42.09  ? 125  ARG A NH1 1 
ATOM 853  N NH2 . ARG A 1 125  ? 183.862 185.725 191.265 1.00 41.38  ? 125  ARG A NH2 1 
ATOM 854  N N   . LYS A 1 126  ? 184.422 194.335 191.545 1.00 36.34  ? 126  LYS A N   1 
ATOM 855  C CA  . LYS A 1 126  ? 184.132 195.706 191.933 1.00 34.24  ? 126  LYS A CA  1 
ATOM 856  C C   . LYS A 1 126  ? 182.623 195.893 192.016 1.00 34.51  ? 126  LYS A C   1 
ATOM 857  O O   . LYS A 1 126  ? 181.940 195.769 190.981 1.00 36.77  ? 126  LYS A O   1 
ATOM 858  C CB  . LYS A 1 126  ? 184.734 196.686 190.926 1.00 39.74  ? 126  LYS A CB  1 
ATOM 859  C CG  . LYS A 1 126  ? 184.269 198.124 191.090 1.00 36.91  ? 126  LYS A CG  1 
ATOM 860  C CD  . LYS A 1 126  ? 184.983 198.814 192.240 1.00 37.53  ? 126  LYS A CD  1 
ATOM 861  C CE  . LYS A 1 126  ? 185.421 200.218 191.852 1.00 39.84  ? 126  LYS A CE  1 
ATOM 862  N NZ  . LYS A 1 126  ? 185.515 201.121 193.032 1.00 36.16  ? 126  LYS A NZ  1 
ATOM 863  N N   . PRO A 1 127  ? 182.049 196.137 193.199 1.00 34.38  ? 127  PRO A N   1 
ATOM 864  C CA  . PRO A 1 127  ? 180.602 196.377 193.257 1.00 29.89  ? 127  PRO A CA  1 
ATOM 865  C C   . PRO A 1 127  ? 180.172 197.582 192.423 1.00 34.49  ? 127  PRO A C   1 
ATOM 866  O O   . PRO A 1 127  ? 180.840 198.616 192.382 1.00 37.67  ? 127  PRO A O   1 
ATOM 867  C CB  . PRO A 1 127  ? 180.331 196.619 194.748 1.00 29.84  ? 127  PRO A CB  1 
ATOM 868  C CG  . PRO A 1 127  ? 181.635 196.354 195.455 1.00 31.22  ? 127  PRO A CG  1 
ATOM 869  C CD  . PRO A 1 127  ? 182.497 195.619 194.483 1.00 37.16  ? 127  PRO A CD  1 
ATOM 870  N N   . ILE A 1 128  ? 179.019 197.443 191.758 1.00 33.40  ? 128  ILE A N   1 
ATOM 871  C CA  . ILE A 1 128  ? 178.461 198.505 190.932 1.00 31.25  ? 128  ILE A CA  1 
ATOM 872  C C   . ILE A 1 128  ? 176.975 198.640 191.226 1.00 32.13  ? 128  ILE A C   1 
ATOM 873  O O   . ILE A 1 128  ? 176.311 197.683 191.638 1.00 34.15  ? 128  ILE A O   1 
ATOM 874  C CB  . ILE A 1 128  ? 178.687 198.255 189.423 1.00 31.68  ? 128  ILE A CB  1 
ATOM 875  C CG1 . ILE A 1 128  ? 178.051 196.933 188.995 1.00 30.32  ? 128  ILE A CG1 1 
ATOM 876  C CG2 . ILE A 1 128  ? 180.171 198.269 189.086 1.00 33.45  ? 128  ILE A CG2 1 
ATOM 877  C CD1 . ILE A 1 128  ? 178.049 196.726 187.501 1.00 31.75  ? 128  ILE A CD1 1 
ATOM 878  N N   . ARG A 1 129  ? 176.456 199.845 191.009 1.00 33.43  ? 129  ARG A N   1 
ATOM 879  C CA  . ARG A 1 129  ? 175.031 200.129 191.099 1.00 31.47  ? 129  ARG A CA  1 
ATOM 880  C C   . ARG A 1 129  ? 174.566 200.691 189.764 1.00 34.14  ? 129  ARG A C   1 
ATOM 881  O O   . ARG A 1 129  ? 175.231 201.556 189.184 1.00 39.26  ? 129  ARG A O   1 
ATOM 882  C CB  . ARG A 1 129  ? 174.722 201.107 192.236 1.00 33.66  ? 129  ARG A CB  1 
ATOM 883  C CG  . ARG A 1 129  ? 174.696 200.468 193.620 1.00 36.45  ? 129  ARG A CG  1 
ATOM 884  C CD  . ARG A 1 129  ? 176.090 200.309 194.201 1.00 38.86  ? 129  ARG A CD  1 
ATOM 885  N NE  . ARG A 1 129  ? 176.732 201.593 194.455 1.00 40.01  ? 129  ARG A NE  1 
ATOM 886  C CZ  . ARG A 1 129  ? 178.022 201.743 194.721 1.00 42.25  ? 129  ARG A CZ  1 
ATOM 887  N NH1 . ARG A 1 129  ? 178.841 200.705 194.776 1.00 38.99  ? 129  ARG A NH1 1 
ATOM 888  N NH2 . ARG A 1 129  ? 178.502 202.964 194.937 1.00 40.37  ? 129  ARG A NH2 1 
ATOM 889  N N   . PHE A 1 130  ? 173.429 200.197 189.284 1.00 25.68  ? 130  PHE A N   1 
ATOM 890  C CA  . PHE A 1 130  ? 172.971 200.471 187.932 1.00 26.25  ? 130  PHE A CA  1 
ATOM 891  C C   . PHE A 1 130  ? 171.450 200.459 187.875 1.00 28.40  ? 130  PHE A C   1 
ATOM 892  O O   . PHE A 1 130  ? 170.777 199.830 188.696 1.00 34.37  ? 130  PHE A O   1 
ATOM 893  C CB  . PHE A 1 130  ? 173.552 199.449 186.943 1.00 25.87  ? 130  PHE A CB  1 
ATOM 894  C CG  . PHE A 1 130  ? 173.109 198.038 187.210 1.00 28.07  ? 130  PHE A CG  1 
ATOM 895  C CD1 . PHE A 1 130  ? 173.847 197.226 188.050 1.00 31.43  ? 130  PHE A CD1 1 
ATOM 896  C CD2 . PHE A 1 130  ? 171.946 197.534 186.658 1.00 29.67  ? 130  PHE A CD2 1 
ATOM 897  C CE1 . PHE A 1 130  ? 173.450 195.935 188.314 1.00 30.21  ? 130  PHE A CE1 1 
ATOM 898  C CE2 . PHE A 1 130  ? 171.538 196.245 186.934 1.00 30.34  ? 130  PHE A CE2 1 
ATOM 899  C CZ  . PHE A 1 130  ? 172.295 195.443 187.754 1.00 30.31  ? 130  PHE A CZ  1 
ATOM 900  N N   . SER A 1 131  ? 170.917 201.169 186.885 1.00 24.93  ? 131  SER A N   1 
ATOM 901  C CA  . SER A 1 131  ? 169.502 201.107 186.563 1.00 21.74  ? 131  SER A CA  1 
ATOM 902  C C   . SER A 1 131  ? 169.228 199.907 185.663 1.00 22.67  ? 131  SER A C   1 
ATOM 903  O O   . SER A 1 131  ? 170.130 199.353 185.031 1.00 24.19  ? 131  SER A O   1 
ATOM 904  C CB  . SER A 1 131  ? 169.045 202.394 185.877 1.00 25.86  ? 131  SER A CB  1 
ATOM 905  O OG  . SER A 1 131  ? 169.169 203.506 186.745 1.00 27.38  ? 131  SER A OG  1 
ATOM 906  N N   . ARG A 1 132  ? 167.960 199.509 185.601 1.00 14.89  ? 132  ARG A N   1 
ATOM 907  C CA  . ARG A 1 132  ? 167.614 198.304 184.860 1.00 11.00  ? 132  ARG A CA  1 
ATOM 908  C C   . ARG A 1 132  ? 166.189 198.399 184.341 1.00 17.91  ? 132  ARG A C   1 
ATOM 909  O O   . ARG A 1 132  ? 165.270 198.730 185.096 1.00 21.96  ? 132  ARG A O   1 
ATOM 910  C CB  . ARG A 1 132  ? 167.770 197.064 185.741 1.00 16.47  ? 132  ARG A CB  1 
ATOM 911  C CG  . ARG A 1 132  ? 167.487 195.769 185.018 1.00 11.42  ? 132  ARG A CG  1 
ATOM 912  C CD  . ARG A 1 132  ? 167.667 194.584 185.938 1.00 13.83  ? 132  ARG A CD  1 
ATOM 913  N NE  . ARG A 1 132  ? 166.723 194.614 187.048 1.00 16.69  ? 132  ARG A NE  1 
ATOM 914  C CZ  . ARG A 1 132  ? 165.473 194.178 186.981 1.00 15.20  ? 132  ARG A CZ  1 
ATOM 915  N NH1 . ARG A 1 132  ? 164.978 193.670 185.865 1.00 17.55  ? 132  ARG A NH1 1 
ATOM 916  N NH2 . ARG A 1 132  ? 164.702 194.252 188.061 1.00 15.16  ? 132  ARG A NH2 1 
ATOM 917  N N   . THR A 1 133  ? 166.016 198.102 183.055 1.00 15.97  ? 133  THR A N   1 
ATOM 918  C CA  . THR A 1 133  ? 164.705 197.927 182.440 1.00 12.36  ? 133  THR A CA  1 
ATOM 919  C C   . THR A 1 133  ? 164.741 196.608 181.684 1.00 17.67  ? 133  THR A C   1 
ATOM 920  O O   . THR A 1 133  ? 165.312 196.531 180.592 1.00 22.33  ? 133  THR A O   1 
ATOM 921  C CB  . THR A 1 133  ? 164.360 199.087 181.507 1.00 14.92  ? 133  THR A CB  1 
ATOM 922  O OG1 . THR A 1 133  ? 164.290 200.304 182.260 1.00 21.85  ? 133  THR A OG1 1 
ATOM 923  C CG2 . THR A 1 133  ? 163.021 198.845 180.831 1.00 16.09  ? 133  THR A CG2 1 
ATOM 924  N N   . GLY A 1 134  ? 164.145 195.573 182.263 1.00 14.32  ? 134  GLY A N   1 
ATOM 925  C CA  . GLY A 1 134  ? 164.270 194.250 181.677 1.00 6.03   ? 134  GLY A CA  1 
ATOM 926  C C   . GLY A 1 134  ? 165.654 193.689 181.934 1.00 11.93  ? 134  GLY A C   1 
ATOM 927  O O   . GLY A 1 134  ? 166.157 193.714 183.062 1.00 18.58  ? 134  GLY A O   1 
ATOM 928  N N   . ALA A 1 135  ? 166.286 193.169 180.884 1.00 12.37  ? 135  ALA A N   1 
ATOM 929  C CA  . ALA A 1 135  ? 167.611 192.575 180.985 1.00 3.56   ? 135  ALA A CA  1 
ATOM 930  C C   . ALA A 1 135  ? 168.725 193.528 180.567 1.00 7.59   ? 135  ALA A C   1 
ATOM 931  O O   . ALA A 1 135  ? 169.891 193.124 180.544 1.00 11.20  ? 135  ALA A O   1 
ATOM 932  C CB  . ALA A 1 135  ? 167.682 191.295 180.152 1.00 3.64   ? 135  ALA A CB  1 
ATOM 933  N N   . ILE A 1 136  ? 168.401 194.776 180.240 1.00 11.32  ? 136  ILE A N   1 
ATOM 934  C CA  . ILE A 1 136  ? 169.381 195.762 179.800 1.00 12.55  ? 136  ILE A CA  1 
ATOM 935  C C   . ILE A 1 136  ? 169.676 196.709 180.952 1.00 12.24  ? 136  ILE A C   1 
ATOM 936  O O   . ILE A 1 136  ? 168.757 197.184 181.630 1.00 20.85  ? 136  ILE A O   1 
ATOM 937  C CB  . ILE A 1 136  ? 168.901 196.525 178.555 1.00 10.18  ? 136  ILE A CB  1 
ATOM 938  C CG1 . ILE A 1 136  ? 168.743 195.555 177.388 1.00 12.84  ? 136  ILE A CG1 1 
ATOM 939  C CG2 . ILE A 1 136  ? 169.859 197.650 178.195 1.00 12.48  ? 136  ILE A CG2 1 
ATOM 940  C CD1 . ILE A 1 136  ? 168.050 196.149 176.221 1.00 20.24  ? 136  ILE A CD1 1 
ATOM 941  N N   . LEU A 1 137  ? 170.959 196.980 181.168 1.00 15.03  ? 137  LEU A N   1 
ATOM 942  C CA  . LEU A 1 137  ? 171.420 197.728 182.324 1.00 16.35  ? 137  LEU A CA  1 
ATOM 943  C C   . LEU A 1 137  ? 171.618 199.192 181.934 1.00 19.40  ? 137  LEU A C   1 
ATOM 944  O O   . LEU A 1 137  ? 171.303 199.608 180.816 1.00 28.31  ? 137  LEU A O   1 
ATOM 945  C CB  . LEU A 1 137  ? 172.712 197.111 182.852 1.00 19.19  ? 137  LEU A CB  1 
ATOM 946  C CG  . LEU A 1 137  ? 172.667 195.607 183.132 1.00 19.76  ? 137  LEU A CG  1 
ATOM 947  C CD1 . LEU A 1 137  ? 173.918 195.149 183.870 1.00 20.20  ? 137  LEU A CD1 1 
ATOM 948  C CD2 . LEU A 1 137  ? 171.399 195.195 183.860 1.00 20.11  ? 137  LEU A CD2 1 
ATOM 949  N N   . THR A 1 138  ? 172.138 199.995 182.864 1.00 26.05  ? 138  THR A N   1 
ATOM 950  C CA  . THR A 1 138  ? 172.557 201.359 182.545 1.00 27.46  ? 138  THR A CA  1 
ATOM 951  C C   . THR A 1 138  ? 173.611 201.757 183.577 1.00 26.86  ? 138  THR A C   1 
ATOM 952  O O   . THR A 1 138  ? 173.269 202.110 184.708 1.00 30.84  ? 138  THR A O   1 
ATOM 953  C CB  . THR A 1 138  ? 171.383 202.326 182.546 1.00 27.04  ? 138  THR A CB  1 
ATOM 954  O OG1 . THR A 1 138  ? 170.415 201.908 181.576 1.00 27.54  ? 138  THR A OG1 1 
ATOM 955  C CG2 . THR A 1 138  ? 171.857 203.729 182.200 1.00 22.50  ? 138  THR A CG2 1 
ATOM 956  N N   . HIS A 1 139  ? 174.878 201.696 183.177 1.00 29.82  ? 139  HIS A N   1 
ATOM 957  C CA  . HIS A 1 139  ? 175.997 202.052 184.040 1.00 33.84  ? 139  HIS A CA  1 
ATOM 958  C C   . HIS A 1 139  ? 176.807 203.144 183.358 1.00 39.42  ? 139  HIS A C   1 
ATOM 959  O O   . HIS A 1 139  ? 177.346 202.927 182.267 1.00 39.05  ? 139  HIS A O   1 
ATOM 960  C CB  . HIS A 1 139  ? 176.870 200.832 184.338 1.00 36.13  ? 139  HIS A CB  1 
ATOM 961  C CG  . HIS A 1 139  ? 177.934 201.085 185.360 1.00 38.05  ? 139  HIS A CG  1 
ATOM 962  N ND1 . HIS A 1 139  ? 177.789 202.008 186.373 1.00 36.31  ? 139  HIS A ND1 1 
ATOM 963  C CD2 . HIS A 1 139  ? 179.159 200.534 185.526 1.00 35.11  ? 139  HIS A CD2 1 
ATOM 964  C CE1 . HIS A 1 139  ? 178.879 202.015 187.118 1.00 38.67  ? 139  HIS A CE1 1 
ATOM 965  N NE2 . HIS A 1 139  ? 179.727 201.130 186.626 1.00 38.90  ? 139  HIS A NE2 1 
ATOM 966  N N   . ASP A 1 140  ? 176.897 204.307 184.006 1.00 43.25  ? 140  ASP A N   1 
ATOM 967  C CA  . ASP A 1 140  ? 177.618 205.464 183.471 1.00 42.26  ? 140  ASP A CA  1 
ATOM 968  C C   . ASP A 1 140  ? 177.093 205.850 182.088 1.00 45.44  ? 140  ASP A C   1 
ATOM 969  O O   . ASP A 1 140  ? 177.856 206.036 181.137 1.00 45.60  ? 140  ASP A O   1 
ATOM 970  C CB  . ASP A 1 140  ? 179.127 205.205 183.435 1.00 41.60  ? 140  ASP A CB  1 
ATOM 971  C CG  . ASP A 1 140  ? 179.705 204.939 184.810 1.00 48.36  ? 140  ASP A CG  1 
ATOM 972  O OD1 . ASP A 1 140  ? 178.936 204.955 185.794 1.00 47.63  ? 140  ASP A OD1 1 
ATOM 973  O OD2 . ASP A 1 140  ? 180.930 204.713 184.907 1.00 49.68  ? 140  ASP A OD2 1 
ATOM 974  N N   . ASN A 1 141  ? 175.769 205.953 181.983 1.00 42.24  ? 141  ASN A N   1 
ATOM 975  C CA  . ASN A 1 141  ? 175.052 206.318 180.763 1.00 41.14  ? 141  ASN A CA  1 
ATOM 976  C C   . ASN A 1 141  ? 175.266 205.325 179.628 1.00 40.25  ? 141  ASN A C   1 
ATOM 977  O O   . ASN A 1 141  ? 174.861 205.594 178.491 1.00 41.26  ? 141  ASN A O   1 
ATOM 978  C CB  . ASN A 1 141  ? 175.423 207.731 180.290 1.00 41.67  ? 141  ASN A CB  1 
ATOM 979  C CG  . ASN A 1 141  ? 175.536 208.719 181.433 1.00 44.92  ? 141  ASN A CG  1 
ATOM 980  O OD1 . ASN A 1 141  ? 174.703 208.735 182.339 1.00 42.79  ? 141  ASN A OD1 1 
ATOM 981  N ND2 . ASN A 1 141  ? 176.571 209.549 181.397 1.00 43.52  ? 141  ASN A ND2 1 
ATOM 982  N N   . GLN A 1 142  ? 175.886 204.182 179.902 1.00 32.79  ? 142  GLN A N   1 
ATOM 983  C CA  . GLN A 1 142  ? 176.158 203.165 178.898 1.00 32.23  ? 142  GLN A CA  1 
ATOM 984  C C   . GLN A 1 142  ? 175.269 201.957 179.153 1.00 31.39  ? 142  GLN A C   1 
ATOM 985  O O   . GLN A 1 142  ? 175.189 201.468 180.284 1.00 35.61  ? 142  GLN A O   1 
ATOM 986  C CB  . GLN A 1 142  ? 177.632 202.753 178.922 1.00 32.64  ? 142  GLN A CB  1 
ATOM 987  C CG  . GLN A 1 142  ? 178.016 201.745 177.854 1.00 31.39  ? 142  GLN A CG  1 
ATOM 988  C CD  . GLN A 1 142  ? 177.816 202.280 176.450 1.00 37.91  ? 142  GLN A CD  1 
ATOM 989  O OE1 . GLN A 1 142  ? 176.866 201.911 175.761 1.00 38.44  ? 142  GLN A OE1 1 
ATOM 990  N NE2 . GLN A 1 142  ? 178.716 203.156 176.019 1.00 38.97  ? 142  GLN A NE2 1 
ATOM 991  N N   . GLN A 1 143  ? 174.600 201.486 178.106 1.00 23.30  ? 143  GLN A N   1 
ATOM 992  C CA  . GLN A 1 143  ? 173.741 200.319 178.228 1.00 21.96  ? 143  GLN A CA  1 
ATOM 993  C C   . GLN A 1 143  ? 174.560 199.040 178.118 1.00 25.39  ? 143  GLN A C   1 
ATOM 994  O O   . GLN A 1 143  ? 175.470 198.935 177.291 1.00 25.95  ? 143  GLN A O   1 
ATOM 995  C CB  . GLN A 1 143  ? 172.652 200.337 177.156 1.00 20.42  ? 143  GLN A CB  1 
ATOM 996  C CG  . GLN A 1 143  ? 171.651 201.467 177.308 1.00 24.34  ? 143  GLN A CG  1 
ATOM 997  C CD  . GLN A 1 143  ? 170.473 201.330 176.364 1.00 28.19  ? 143  GLN A CD  1 
ATOM 998  O OE1 . GLN A 1 143  ? 170.497 200.522 175.436 1.00 30.93  ? 143  GLN A OE1 1 
ATOM 999  N NE2 . GLN A 1 143  ? 169.432 202.121 176.599 1.00 24.98  ? 143  GLN A NE2 1 
ATOM 1000 N N   . TYR A 1 144  ? 174.235 198.072 178.968 1.00 21.57  ? 144  TYR A N   1 
ATOM 1001 C CA  . TYR A 1 144  ? 174.829 196.745 178.943 1.00 16.23  ? 144  TYR A CA  1 
ATOM 1002 C C   . TYR A 1 144  ? 173.707 195.717 178.940 1.00 12.77  ? 144  TYR A C   1 
ATOM 1003 O O   . TYR A 1 144  ? 172.523 196.060 178.971 1.00 17.72  ? 144  TYR A O   1 
ATOM 1004 C CB  . TYR A 1 144  ? 175.770 196.528 180.134 1.00 19.38  ? 144  TYR A CB  1 
ATOM 1005 C CG  . TYR A 1 144  ? 176.909 197.517 180.207 1.00 22.25  ? 144  TYR A CG  1 
ATOM 1006 C CD1 . TYR A 1 144  ? 176.767 198.720 180.882 1.00 20.44  ? 144  TYR A CD1 1 
ATOM 1007 C CD2 . TYR A 1 144  ? 178.128 197.245 179.603 1.00 20.38  ? 144  TYR A CD2 1 
ATOM 1008 C CE1 . TYR A 1 144  ? 177.804 199.627 180.952 1.00 19.31  ? 144  TYR A CE1 1 
ATOM 1009 C CE2 . TYR A 1 144  ? 179.172 198.146 179.667 1.00 20.96  ? 144  TYR A CE2 1 
ATOM 1010 C CZ  . TYR A 1 144  ? 179.004 199.335 180.343 1.00 24.51  ? 144  TYR A CZ  1 
ATOM 1011 O OH  . TYR A 1 144  ? 180.041 200.236 180.410 1.00 26.47  ? 144  TYR A OH  1 
ATOM 1012 N N   . LEU A 1 145  ? 174.082 194.444 178.902 1.00 9.31   ? 145  LEU A N   1 
ATOM 1013 C CA  . LEU A 1 145  ? 173.115 193.357 178.898 1.00 13.04  ? 145  LEU A CA  1 
ATOM 1014 C C   . LEU A 1 145  ? 173.487 192.351 179.975 1.00 14.53  ? 145  LEU A C   1 
ATOM 1015 O O   . LEU A 1 145  ? 174.652 191.960 180.088 1.00 21.18  ? 145  LEU A O   1 
ATOM 1016 C CB  . LEU A 1 145  ? 173.057 192.677 177.527 1.00 12.16  ? 145  LEU A CB  1 
ATOM 1017 C CG  . LEU A 1 145  ? 172.004 191.583 177.357 1.00 8.40   ? 145  LEU A CG  1 
ATOM 1018 C CD1 . LEU A 1 145  ? 170.628 192.199 177.217 1.00 9.19   ? 145  LEU A CD1 1 
ATOM 1019 C CD2 . LEU A 1 145  ? 172.329 190.721 176.156 1.00 11.16  ? 145  LEU A CD2 1 
ATOM 1020 N N   . LEU A 1 146  ? 172.502 191.945 180.770 1.00 6.26   ? 146  LEU A N   1 
ATOM 1021 C CA  . LEU A 1 146  ? 172.721 190.876 181.731 1.00 5.09   ? 146  LEU A CA  1 
ATOM 1022 C C   . LEU A 1 146  ? 172.982 189.565 181.006 1.00 9.89   ? 146  LEU A C   1 
ATOM 1023 O O   . LEU A 1 146  ? 172.428 189.309 179.933 1.00 14.82  ? 146  LEU A O   1 
ATOM 1024 C CB  . LEU A 1 146  ? 171.514 190.722 182.655 1.00 8.48   ? 146  LEU A CB  1 
ATOM 1025 C CG  . LEU A 1 146  ? 171.455 191.606 183.898 1.00 3.75   ? 146  LEU A CG  1 
ATOM 1026 C CD1 . LEU A 1 146  ? 170.170 191.351 184.663 1.00 10.91  ? 146  LEU A CD1 1 
ATOM 1027 C CD2 . LEU A 1 146  ? 172.661 191.360 184.781 1.00 3.24   ? 146  LEU A CD2 1 
ATOM 1028 N N   . SER A 1 147  ? 173.835 188.733 181.595 1.00 11.62  ? 147  SER A N   1 
ATOM 1029 C CA  . SER A 1 147  ? 174.038 187.392 181.075 1.00 0.00   ? 147  SER A CA  1 
ATOM 1030 C C   . SER A 1 147  ? 172.728 186.612 181.120 1.00 5.70   ? 147  SER A C   1 
ATOM 1031 O O   . SER A 1 147  ? 171.800 186.944 181.860 1.00 13.33  ? 147  SER A O   1 
ATOM 1032 C CB  . SER A 1 147  ? 175.109 186.660 181.882 1.00 6.78   ? 147  SER A CB  1 
ATOM 1033 O OG  . SER A 1 147  ? 176.369 187.293 181.753 1.00 22.24  ? 147  SER A OG  1 
ATOM 1034 N N   . ARG A 1 148  ? 172.657 185.563 180.300 1.00 6.36   ? 148  ARG A N   1 
ATOM 1035 C CA  . ARG A 1 148  ? 171.489 184.691 180.330 1.00 1.92   ? 148  ARG A CA  1 
ATOM 1036 C C   . ARG A 1 148  ? 171.319 184.062 181.706 1.00 5.26   ? 148  ARG A C   1 
ATOM 1037 O O   . ARG A 1 148  ? 170.202 183.981 182.231 1.00 10.09  ? 148  ARG A O   1 
ATOM 1038 C CB  . ARG A 1 148  ? 171.619 183.613 179.256 1.00 6.53   ? 148  ARG A CB  1 
ATOM 1039 C CG  . ARG A 1 148  ? 170.317 182.938 178.872 1.00 9.22   ? 148  ARG A CG  1 
ATOM 1040 C CD  . ARG A 1 148  ? 170.586 181.747 177.969 1.00 10.08  ? 148  ARG A CD  1 
ATOM 1041 N NE  . ARG A 1 148  ? 169.423 181.379 177.171 1.00 13.32  ? 148  ARG A NE  1 
ATOM 1042 C CZ  . ARG A 1 148  ? 169.489 180.816 175.972 1.00 16.64  ? 148  ARG A CZ  1 
ATOM 1043 N NH1 . ARG A 1 148  ? 170.650 180.549 175.397 1.00 9.79   ? 148  ARG A NH1 1 
ATOM 1044 N NH2 . ARG A 1 148  ? 168.362 180.512 175.335 1.00 17.61  ? 148  ARG A NH2 1 
ATOM 1045 N N   . GLU A 1 149  ? 172.425 183.627 182.312 1.00 8.48   ? 149  GLU A N   1 
ATOM 1046 C CA  . GLU A 1 149  ? 172.366 183.027 183.640 1.00 4.41   ? 149  GLU A CA  1 
ATOM 1047 C C   . GLU A 1 149  ? 172.007 184.060 184.702 1.00 2.04   ? 149  GLU A C   1 
ATOM 1048 O O   . GLU A 1 149  ? 171.207 183.780 185.600 1.00 9.03   ? 149  GLU A O   1 
ATOM 1049 C CB  . GLU A 1 149  ? 173.699 182.353 183.970 1.00 5.20   ? 149  GLU A CB  1 
ATOM 1050 C CG  . GLU A 1 149  ? 174.158 181.309 182.955 1.00 8.10   ? 149  GLU A CG  1 
ATOM 1051 C CD  . GLU A 1 149  ? 174.734 181.918 181.688 1.00 12.77  ? 149  GLU A CD  1 
ATOM 1052 O OE1 . GLU A 1 149  ? 174.492 181.363 180.596 1.00 15.67  ? 149  GLU A OE1 1 
ATOM 1053 O OE2 . GLU A 1 149  ? 175.425 182.953 181.784 1.00 11.65  ? 149  GLU A OE2 1 
ATOM 1054 N N   . ASN A 1 150  ? 172.590 185.257 184.620 1.00 0.00   ? 150  ASN A N   1 
ATOM 1055 C CA  . ASN A 1 150  ? 172.250 186.304 185.578 1.00 0.00   ? 150  ASN A CA  1 
ATOM 1056 C C   . ASN A 1 150  ? 170.811 186.769 185.401 1.00 3.78   ? 150  ASN A C   1 
ATOM 1057 O O   . ASN A 1 150  ? 170.119 187.056 186.386 1.00 17.49  ? 150  ASN A O   1 
ATOM 1058 C CB  . ASN A 1 150  ? 173.218 187.477 185.443 1.00 4.80   ? 150  ASN A CB  1 
ATOM 1059 C CG  . ASN A 1 150  ? 174.558 187.199 186.087 1.00 8.14   ? 150  ASN A CG  1 
ATOM 1060 O OD1 . ASN A 1 150  ? 174.662 186.372 186.992 1.00 10.40  ? 150  ASN A OD1 1 
ATOM 1061 N ND2 . ASN A 1 150  ? 175.592 187.889 185.626 1.00 14.67  ? 150  ASN A ND2 1 
ATOM 1062 N N   . TRP A 1 151  ? 170.341 186.851 184.155 1.00 5.52   ? 151  TRP A N   1 
ATOM 1063 C CA  . TRP A 1 151  ? 168.940 187.185 183.924 1.00 1.56   ? 151  TRP A CA  1 
ATOM 1064 C C   . TRP A 1 151  ? 168.023 186.117 184.504 1.00 5.59   ? 151  TRP A C   1 
ATOM 1065 O O   . TRP A 1 151  ? 166.993 186.437 185.107 1.00 16.23  ? 151  TRP A O   1 
ATOM 1066 C CB  . TRP A 1 151  ? 168.676 187.368 182.430 1.00 0.94   ? 151  TRP A CB  1 
ATOM 1067 C CG  . TRP A 1 151  ? 167.227 187.554 182.105 1.00 1.80   ? 151  TRP A CG  1 
ATOM 1068 C CD1 . TRP A 1 151  ? 166.441 186.727 181.358 1.00 5.91   ? 151  TRP A CD1 1 
ATOM 1069 C CD2 . TRP A 1 151  ? 166.386 188.635 182.524 1.00 1.79   ? 151  TRP A CD2 1 
ATOM 1070 N NE1 . TRP A 1 151  ? 165.165 187.227 181.283 1.00 5.14   ? 151  TRP A NE1 1 
ATOM 1071 C CE2 . TRP A 1 151  ? 165.105 188.398 181.991 1.00 0.00   ? 151  TRP A CE2 1 
ATOM 1072 C CE3 . TRP A 1 151  ? 166.593 189.780 183.297 1.00 9.06   ? 151  TRP A CE3 1 
ATOM 1073 C CZ2 . TRP A 1 151  ? 164.037 189.264 182.205 1.00 4.69   ? 151  TRP A CZ2 1 
ATOM 1074 C CZ3 . TRP A 1 151  ? 165.532 190.637 183.510 1.00 8.24   ? 151  TRP A CZ3 1 
ATOM 1075 C CH2 . TRP A 1 151  ? 164.270 190.375 182.965 1.00 8.20   ? 151  TRP A CH2 1 
ATOM 1076 N N   . ALA A 1 152  ? 168.381 184.842 184.336 1.00 3.77   ? 152  ALA A N   1 
ATOM 1077 C CA  . ALA A 1 152  ? 167.583 183.766 184.914 1.00 0.00   ? 152  ALA A CA  1 
ATOM 1078 C C   . ALA A 1 152  ? 167.573 183.838 186.436 1.00 3.01   ? 152  ALA A C   1 
ATOM 1079 O O   . ALA A 1 152  ? 166.537 183.609 187.068 1.00 11.86  ? 152  ALA A O   1 
ATOM 1080 C CB  . ALA A 1 152  ? 168.110 182.411 184.443 1.00 3.53   ? 152  ALA A CB  1 
ATOM 1081 N N   . LEU A 1 153  ? 168.721 184.147 187.041 1.00 2.03   ? 153  LEU A N   1 
ATOM 1082 C CA  . LEU A 1 153  ? 168.787 184.293 188.493 1.00 4.82   ? 153  LEU A CA  1 
ATOM 1083 C C   . LEU A 1 153  ? 167.898 185.434 188.976 1.00 4.31   ? 153  LEU A C   1 
ATOM 1084 O O   . LEU A 1 153  ? 167.154 185.288 189.958 1.00 14.98  ? 153  LEU A O   1 
ATOM 1085 C CB  . LEU A 1 153  ? 170.237 184.528 188.917 1.00 3.56   ? 153  LEU A CB  1 
ATOM 1086 C CG  . LEU A 1 153  ? 170.548 184.795 190.391 1.00 5.48   ? 153  LEU A CG  1 
ATOM 1087 C CD1 . LEU A 1 153  ? 169.788 183.845 191.298 1.00 3.39   ? 153  LEU A CD1 1 
ATOM 1088 C CD2 . LEU A 1 153  ? 172.041 184.710 190.642 1.00 2.81   ? 153  LEU A CD2 1 
ATOM 1089 N N   . LEU A 1 154  ? 167.967 186.581 188.298 1.00 0.68   ? 154  LEU A N   1 
ATOM 1090 C CA  . LEU A 1 154  ? 167.133 187.718 188.671 1.00 5.02   ? 154  LEU A CA  1 
ATOM 1091 C C   . LEU A 1 154  ? 165.655 187.388 188.512 1.00 4.77   ? 154  LEU A C   1 
ATOM 1092 O O   . LEU A 1 154  ? 164.830 187.758 189.358 1.00 6.41   ? 154  LEU A O   1 
ATOM 1093 C CB  . LEU A 1 154  ? 167.516 188.929 187.825 1.00 3.61   ? 154  LEU A CB  1 
ATOM 1094 C CG  . LEU A 1 154  ? 166.807 190.251 188.097 1.00 9.19   ? 154  LEU A CG  1 
ATOM 1095 C CD1 . LEU A 1 154  ? 167.098 190.738 189.503 1.00 12.69  ? 154  LEU A CD1 1 
ATOM 1096 C CD2 . LEU A 1 154  ? 167.263 191.263 187.078 1.00 9.28   ? 154  LEU A CD2 1 
ATOM 1097 N N   . GLN A 1 155  ? 165.304 186.685 187.433 1.00 3.58   ? 155  GLN A N   1 
ATOM 1098 C CA  . GLN A 1 155  ? 163.926 186.251 187.244 1.00 4.30   ? 155  GLN A CA  1 
ATOM 1099 C C   . GLN A 1 155  ? 163.487 185.316 188.359 1.00 4.06   ? 155  GLN A C   1 
ATOM 1100 O O   . GLN A 1 155  ? 162.353 185.403 188.832 1.00 10.14  ? 155  GLN A O   1 
ATOM 1101 C CB  . GLN A 1 155  ? 163.764 185.572 185.885 1.00 4.84   ? 155  GLN A CB  1 
ATOM 1102 C CG  . GLN A 1 155  ? 163.890 186.510 184.704 1.00 4.68   ? 155  GLN A CG  1 
ATOM 1103 C CD  . GLN A 1 155  ? 162.562 187.105 184.295 1.00 11.51  ? 155  GLN A CD  1 
ATOM 1104 O OE1 . GLN A 1 155  ? 162.214 188.213 184.702 1.00 10.37  ? 155  GLN A OE1 1 
ATOM 1105 N NE2 . GLN A 1 155  ? 161.810 186.372 183.483 1.00 10.87  ? 155  GLN A NE2 1 
ATOM 1106 N N   . ALA A 1 156  ? 164.364 184.405 188.783 1.00 11.13  ? 156  ALA A N   1 
ATOM 1107 C CA  . ALA A 1 156  ? 164.009 183.489 189.863 1.00 5.84   ? 156  ALA A CA  1 
ATOM 1108 C C   . ALA A 1 156  ? 163.744 184.241 191.161 1.00 0.55   ? 156  ALA A C   1 
ATOM 1109 O O   . ALA A 1 156  ? 162.769 183.952 191.868 1.00 4.43   ? 156  ALA A O   1 
ATOM 1110 C CB  . ALA A 1 156  ? 165.114 182.452 190.055 1.00 0.00   ? 156  ALA A CB  1 
ATOM 1111 N N   . THR A 1 157  ? 164.596 185.216 191.489 1.00 3.39   ? 157  THR A N   1 
ATOM 1112 C CA  . THR A 1 157  ? 164.364 186.000 192.702 1.00 5.26   ? 157  THR A CA  1 
ATOM 1113 C C   . THR A 1 157  ? 163.063 186.792 192.614 1.00 11.53  ? 157  THR A C   1 
ATOM 1114 O O   . THR A 1 157  ? 162.294 186.848 193.583 1.00 13.53  ? 157  THR A O   1 
ATOM 1115 C CB  . THR A 1 157  ? 165.540 186.937 192.982 1.00 0.00   ? 157  THR A CB  1 
ATOM 1116 O OG1 . THR A 1 157  ? 165.697 187.858 191.895 1.00 10.16  ? 157  THR A OG1 1 
ATOM 1117 C CG2 . THR A 1 157  ? 166.821 186.152 193.192 1.00 2.23   ? 157  THR A CG2 1 
ATOM 1118 N N   . GLU A 1 158  ? 162.791 187.406 191.458 1.00 12.66  ? 158  GLU A N   1 
ATOM 1119 C CA  . GLU A 1 158  ? 161.558 188.178 191.317 1.00 9.35   ? 158  GLU A CA  1 
ATOM 1120 C C   . GLU A 1 158  ? 160.326 187.280 191.358 1.00 16.13  ? 158  GLU A C   1 
ATOM 1121 O O   . GLU A 1 158  ? 159.288 187.669 191.907 1.00 22.97  ? 158  GLU A O   1 
ATOM 1122 C CB  . GLU A 1 158  ? 161.592 188.999 190.030 1.00 8.03   ? 158  GLU A CB  1 
ATOM 1123 C CG  . GLU A 1 158  ? 162.672 190.069 190.019 1.00 11.88  ? 158  GLU A CG  1 
ATOM 1124 C CD  . GLU A 1 158  ? 162.664 190.900 188.753 1.00 20.79  ? 158  GLU A CD  1 
ATOM 1125 O OE1 . GLU A 1 158  ? 162.245 190.379 187.698 1.00 20.06  ? 158  GLU A OE1 1 
ATOM 1126 O OE2 . GLU A 1 158  ? 163.078 192.077 188.813 1.00 22.73  ? 158  GLU A OE2 1 
ATOM 1127 N N   . GLN A 1 159  ? 160.414 186.079 190.783 1.00 11.82  ? 159  GLN A N   1 
ATOM 1128 C CA  . GLN A 1 159  ? 159.296 185.143 190.843 1.00 9.67   ? 159  GLN A CA  1 
ATOM 1129 C C   . GLN A 1 159  ? 159.047 184.673 192.268 1.00 12.78  ? 159  GLN A C   1 
ATOM 1130 O O   . GLN A 1 159  ? 157.891 184.531 192.683 1.00 23.21  ? 159  GLN A O   1 
ATOM 1131 C CB  . GLN A 1 159  ? 159.547 183.953 189.916 1.00 8.99   ? 159  GLN A CB  1 
ATOM 1132 C CG  . GLN A 1 159  ? 159.556 184.314 188.440 1.00 15.63  ? 159  GLN A CG  1 
ATOM 1133 C CD  . GLN A 1 159  ? 159.827 183.122 187.546 1.00 20.52  ? 159  GLN A CD  1 
ATOM 1134 O OE1 . GLN A 1 159  ? 160.076 182.016 188.025 1.00 19.50  ? 159  GLN A OE1 1 
ATOM 1135 N NE2 . GLN A 1 159  ? 159.788 183.344 186.237 1.00 16.06  ? 159  GLN A NE2 1 
ATOM 1136 N N   . LEU A 1 160  ? 160.112 184.429 193.038 1.00 11.87  ? 160  LEU A N   1 
ATOM 1137 C CA  . LEU A 1 160  ? 159.915 184.125 194.452 1.00 12.04  ? 160  LEU A CA  1 
ATOM 1138 C C   . LEU A 1 160  ? 159.240 185.284 195.171 1.00 16.82  ? 160  LEU A C   1 
ATOM 1139 O O   . LEU A 1 160  ? 158.294 185.077 195.937 1.00 22.14  ? 160  LEU A O   1 
ATOM 1140 C CB  . LEU A 1 160  ? 161.242 183.786 195.130 1.00 13.31  ? 160  LEU A CB  1 
ATOM 1141 C CG  . LEU A 1 160  ? 161.061 183.365 196.594 1.00 12.27  ? 160  LEU A CG  1 
ATOM 1142 C CD1 . LEU A 1 160  ? 160.099 182.196 196.722 1.00 14.19  ? 160  LEU A CD1 1 
ATOM 1143 C CD2 . LEU A 1 160  ? 162.387 183.039 197.254 1.00 13.15  ? 160  LEU A CD2 1 
ATOM 1144 N N   . SER A 1 161  ? 159.697 186.513 194.922 1.00 19.00  ? 161  SER A N   1 
ATOM 1145 C CA  . SER A 1 161  ? 159.096 187.667 195.586 1.00 17.27  ? 161  SER A CA  1 
ATOM 1146 C C   . SER A 1 161  ? 157.618 187.795 195.236 1.00 20.53  ? 161  SER A C   1 
ATOM 1147 O O   . SER A 1 161  ? 156.792 188.113 196.100 1.00 23.26  ? 161  SER A O   1 
ATOM 1148 C CB  . SER A 1 161  ? 159.851 188.941 195.212 1.00 21.01  ? 161  SER A CB  1 
ATOM 1149 O OG  . SER A 1 161  ? 161.209 188.859 195.606 1.00 23.80  ? 161  SER A OG  1 
ATOM 1150 N N   . ALA A 1 162  ? 157.266 187.553 193.972 1.00 19.86  ? 162  ALA A N   1 
ATOM 1151 C CA  . ALA A 1 162  ? 155.867 187.610 193.561 1.00 23.84  ? 162  ALA A CA  1 
ATOM 1152 C C   . ALA A 1 162  ? 155.049 186.490 194.195 1.00 25.42  ? 162  ALA A C   1 
ATOM 1153 O O   . ALA A 1 162  ? 153.887 186.695 194.562 1.00 29.17  ? 162  ALA A O   1 
ATOM 1154 C CB  . ALA A 1 162  ? 155.766 187.551 192.038 1.00 20.46  ? 162  ALA A CB  1 
ATOM 1155 N N   . GLN A 1 163  ? 155.630 185.295 194.317 1.00 22.98  ? 163  GLN A N   1 
ATOM 1156 C CA  . GLN A 1 163  ? 154.896 184.176 194.899 1.00 21.20  ? 163  GLN A CA  1 
ATOM 1157 C C   . GLN A 1 163  ? 154.694 184.350 196.400 1.00 24.82  ? 163  GLN A C   1 
ATOM 1158 O O   . GLN A 1 163  ? 153.696 183.869 196.948 1.00 27.02  ? 163  GLN A O   1 
ATOM 1159 C CB  . GLN A 1 163  ? 155.623 182.865 194.607 1.00 22.56  ? 163  GLN A CB  1 
ATOM 1160 C CG  . GLN A 1 163  ? 155.199 182.190 193.314 1.00 23.83  ? 163  GLN A CG  1 
ATOM 1161 C CD  . GLN A 1 163  ? 154.049 181.222 193.511 1.00 28.76  ? 163  GLN A CD  1 
ATOM 1162 O OE1 . GLN A 1 163  ? 153.522 181.084 194.614 1.00 28.40  ? 163  GLN A OE1 1 
ATOM 1163 N NE2 . GLN A 1 163  ? 153.655 180.544 192.439 1.00 29.22  ? 163  GLN A NE2 1 
ATOM 1164 N N   . GLN A 1 164  ? 155.625 185.022 197.081 1.00 22.84  ? 164  GLN A N   1 
ATOM 1165 C CA  . GLN A 1 164  ? 155.493 185.220 198.520 1.00 24.52  ? 164  GLN A CA  1 
ATOM 1166 C C   . GLN A 1 164  ? 154.430 186.254 198.869 1.00 27.41  ? 164  GLN A C   1 
ATOM 1167 O O   . GLN A 1 164  ? 153.817 186.164 199.939 1.00 27.92  ? 164  GLN A O   1 
ATOM 1168 C CB  . GLN A 1 164  ? 156.838 185.623 199.125 1.00 19.18  ? 164  GLN A CB  1 
ATOM 1169 C CG  . GLN A 1 164  ? 157.952 184.637 198.842 1.00 20.03  ? 164  GLN A CG  1 
ATOM 1170 C CD  . GLN A 1 164  ? 159.178 184.882 199.686 1.00 24.74  ? 164  GLN A CD  1 
ATOM 1171 O OE1 . GLN A 1 164  ? 159.742 185.975 199.678 1.00 25.92  ? 164  GLN A OE1 1 
ATOM 1172 N NE2 . GLN A 1 164  ? 159.608 183.860 200.415 1.00 26.15  ? 164  GLN A NE2 1 
ATOM 1173 N N   . ILE A 1 165  ? 154.197 187.241 197.997 1.00 24.48  ? 165  ILE A N   1 
ATOM 1174 C CA  . ILE A 1 165  ? 153.126 188.205 198.225 1.00 25.94  ? 165  ILE A CA  1 
ATOM 1175 C C   . ILE A 1 165  ? 151.783 187.700 197.721 1.00 28.73  ? 165  ILE A C   1 
ATOM 1176 O O   . ILE A 1 165  ? 150.788 188.435 197.790 1.00 30.64  ? 165  ILE A O   1 
ATOM 1177 C CB  . ILE A 1 165  ? 153.440 189.568 197.574 1.00 28.67  ? 165  ILE A CB  1 
ATOM 1178 C CG1 . ILE A 1 165  ? 153.565 189.426 196.057 1.00 27.99  ? 165  ILE A CG1 1 
ATOM 1179 C CG2 . ILE A 1 165  ? 154.711 190.158 198.163 1.00 26.23  ? 165  ILE A CG2 1 
ATOM 1180 C CD1 . ILE A 1 165  ? 153.642 190.747 195.324 1.00 26.56  ? 165  ILE A CD1 1 
ATOM 1181 N N   . GLN A 1 166  ? 151.722 186.472 197.217 1.00 30.82  ? 166  GLN A N   1 
ATOM 1182 C CA  . GLN A 1 166  ? 150.482 185.859 196.761 1.00 32.08  ? 166  GLN A CA  1 
ATOM 1183 C C   . GLN A 1 166  ? 150.097 184.635 197.574 1.00 31.05  ? 166  GLN A C   1 
ATOM 1184 O O   . GLN A 1 166  ? 148.911 184.435 197.852 1.00 33.49  ? 166  GLN A O   1 
ATOM 1185 C CB  . GLN A 1 166  ? 150.597 185.487 195.272 1.00 26.92  ? 166  GLN A CB  1 
ATOM 1186 C CG  . GLN A 1 166  ? 149.303 185.015 194.619 1.00 29.55  ? 166  GLN A CG  1 
ATOM 1187 C CD  . GLN A 1 166  ? 149.052 183.531 194.806 1.00 35.04  ? 166  GLN A CD  1 
ATOM 1188 O OE1 . GLN A 1 166  ? 149.989 182.743 194.920 1.00 36.03  ? 166  GLN A OE1 1 
ATOM 1189 N NE2 . GLN A 1 166  ? 147.782 183.144 194.836 1.00 35.79  ? 166  GLN A NE2 1 
ATOM 1190 N N   . THR A 1 167  ? 151.064 183.807 197.968 1.00 30.78  ? 167  THR A N   1 
ATOM 1191 C CA  . THR A 1 167  ? 150.798 182.676 198.857 1.00 30.06  ? 167  THR A CA  1 
ATOM 1192 C C   . THR A 1 167  ? 152.018 182.422 199.745 1.00 28.37  ? 167  THR A C   1 
ATOM 1193 O O   . THR A 1 167  ? 152.949 181.696 199.374 1.00 28.73  ? 167  THR A O   1 
ATOM 1194 C CB  . THR A 1 167  ? 150.375 181.426 198.077 1.00 28.79  ? 167  THR A CB  1 
ATOM 1195 O OG1 . THR A 1 167  ? 149.972 180.391 198.984 1.00 34.09  ? 167  THR A OG1 1 
ATOM 1196 C CG2 . THR A 1 167  ? 151.445 180.917 197.092 1.00 23.58  ? 167  THR A CG2 1 
ATOM 1197 N N   . PRO A 1 168  ? 152.058 183.043 200.921 1.00 26.83  ? 168  PRO A N   1 
ATOM 1198 C CA  . PRO A 1 168  ? 153.124 182.739 201.882 1.00 29.99  ? 168  PRO A CA  1 
ATOM 1199 C C   . PRO A 1 168  ? 153.076 181.281 202.318 1.00 34.10  ? 168  PRO A C   1 
ATOM 1200 O O   . PRO A 1 168  ? 152.081 180.574 202.145 1.00 32.02  ? 168  PRO A O   1 
ATOM 1201 C CB  . PRO A 1 168  ? 152.832 183.674 203.056 1.00 27.97  ? 168  PRO A CB  1 
ATOM 1202 C CG  . PRO A 1 168  ? 152.036 184.789 202.486 1.00 30.02  ? 168  PRO A CG  1 
ATOM 1203 C CD  . PRO A 1 168  ? 151.386 184.320 201.212 1.00 31.30  ? 168  PRO A CD  1 
ATOM 1204 N N   . GLY A 1 169  ? 154.187 180.834 202.896 1.00 27.01  ? 169  GLY A N   1 
ATOM 1205 C CA  . GLY A 1 169  ? 154.286 179.470 203.373 1.00 22.48  ? 169  GLY A CA  1 
ATOM 1206 C C   . GLY A 1 169  ? 155.643 178.850 203.117 1.00 23.26  ? 169  GLY A C   1 
ATOM 1207 O O   . GLY A 1 169  ? 156.457 179.409 202.378 1.00 27.99  ? 169  GLY A O   1 
ATOM 1208 N N   . GLU A 1 170  ? 155.900 177.689 203.724 1.00 24.76  ? 170  GLU A N   1 
ATOM 1209 C CA  . GLU A 1 170  ? 157.197 177.044 203.553 1.00 20.15  ? 170  GLU A CA  1 
ATOM 1210 C C   . GLU A 1 170  ? 157.328 176.383 202.187 1.00 17.13  ? 170  GLU A C   1 
ATOM 1211 O O   . GLU A 1 170  ? 158.443 176.251 201.674 1.00 20.35  ? 170  GLU A O   1 
ATOM 1212 C CB  . GLU A 1 170  ? 157.430 176.020 204.664 1.00 20.77  ? 170  GLU A CB  1 
ATOM 1213 C CG  . GLU A 1 170  ? 158.867 175.532 204.758 1.00 23.03  ? 170  GLU A CG  1 
ATOM 1214 C CD  . GLU A 1 170  ? 159.190 174.910 206.101 1.00 28.34  ? 170  GLU A CD  1 
ATOM 1215 O OE1 . GLU A 1 170  ? 160.377 174.607 206.345 1.00 28.44  ? 170  GLU A OE1 1 
ATOM 1216 O OE2 . GLU A 1 170  ? 158.260 174.725 206.912 1.00 27.28  ? 170  GLU A OE2 1 
ATOM 1217 N N   . THR A 1 171  ? 156.216 175.952 201.588 1.00 16.88  ? 171  THR A N   1 
ATOM 1218 C CA  . THR A 1 171  ? 156.286 175.335 200.266 1.00 19.99  ? 171  THR A CA  1 
ATOM 1219 C C   . THR A 1 171  ? 156.718 176.344 199.209 1.00 21.73  ? 171  THR A C   1 
ATOM 1220 O O   . THR A 1 171  ? 157.575 176.047 198.367 1.00 26.94  ? 171  THR A O   1 
ATOM 1221 C CB  . THR A 1 171  ? 154.935 174.720 199.902 1.00 23.67  ? 171  THR A CB  1 
ATOM 1222 O OG1 . THR A 1 171  ? 154.588 173.720 200.867 1.00 26.82  ? 171  THR A OG1 1 
ATOM 1223 C CG2 . THR A 1 171  ? 154.991 174.083 198.525 1.00 19.44  ? 171  THR A CG2 1 
ATOM 1224 N N   . THR A 1 172  ? 156.135 177.545 199.239 1.00 19.90  ? 172  THR A N   1 
ATOM 1225 C CA  . THR A 1 172  ? 156.562 178.602 198.329 1.00 21.65  ? 172  THR A CA  1 
ATOM 1226 C C   . THR A 1 172  ? 158.027 178.947 198.549 1.00 19.34  ? 172  THR A C   1 
ATOM 1227 O O   . THR A 1 172  ? 158.789 179.110 197.587 1.00 23.18  ? 172  THR A O   1 
ATOM 1228 C CB  . THR A 1 172  ? 155.690 179.843 198.522 1.00 25.85  ? 172  THR A CB  1 
ATOM 1229 O OG1 . THR A 1 172  ? 154.321 179.519 198.249 1.00 28.71  ? 172  THR A OG1 1 
ATOM 1230 C CG2 . THR A 1 172  ? 156.141 180.964 197.603 1.00 22.65  ? 172  THR A CG2 1 
ATOM 1231 N N   . ASN A 1 173  ? 158.437 179.050 199.815 1.00 13.19  ? 173  ASN A N   1 
ATOM 1232 C CA  . ASN A 1 173  ? 159.829 179.339 200.133 1.00 12.56  ? 173  ASN A CA  1 
ATOM 1233 C C   . ASN A 1 173  ? 160.757 178.285 199.549 1.00 15.30  ? 173  ASN A C   1 
ATOM 1234 O O   . ASN A 1 173  ? 161.761 178.616 198.911 1.00 21.72  ? 173  ASN A O   1 
ATOM 1235 C CB  . ASN A 1 173  ? 160.006 179.416 201.648 1.00 13.99  ? 173  ASN A CB  1 
ATOM 1236 C CG  . ASN A 1 173  ? 159.524 180.726 202.225 1.00 20.34  ? 173  ASN A CG  1 
ATOM 1237 O OD1 . ASN A 1 173  ? 158.941 181.552 201.524 1.00 22.93  ? 173  ASN A OD1 1 
ATOM 1238 N ND2 . ASN A 1 173  ? 159.743 180.914 203.519 1.00 16.49  ? 173  ASN A ND2 1 
ATOM 1239 N N   . GLN A 1 174  ? 160.424 177.007 199.741 1.00 14.56  ? 174  GLN A N   1 
ATOM 1240 C CA  . GLN A 1 174  ? 161.287 175.930 199.270 1.00 12.42  ? 174  GLN A CA  1 
ATOM 1241 C C   . GLN A 1 174  ? 161.356 175.891 197.750 1.00 9.11   ? 174  GLN A C   1 
ATOM 1242 O O   . GLN A 1 174  ? 162.442 175.739 197.183 1.00 15.09  ? 174  GLN A O   1 
ATOM 1243 C CB  . GLN A 1 174  ? 160.803 174.589 199.821 1.00 13.76  ? 174  GLN A CB  1 
ATOM 1244 C CG  . GLN A 1 174  ? 161.372 174.253 201.189 1.00 18.74  ? 174  GLN A CG  1 
ATOM 1245 C CD  . GLN A 1 174  ? 160.581 173.183 201.908 1.00 20.46  ? 174  GLN A CD  1 
ATOM 1246 O OE1 . GLN A 1 174  ? 159.849 172.414 201.286 1.00 17.06  ? 174  GLN A OE1 1 
ATOM 1247 N NE2 . GLN A 1 174  ? 160.721 173.129 203.227 1.00 17.14  ? 174  GLN A NE2 1 
ATOM 1248 N N   . LEU A 1 175  ? 160.215 176.028 197.071 1.00 6.30   ? 175  LEU A N   1 
ATOM 1249 C CA  . LEU A 1 175  ? 160.223 175.984 195.610 1.00 12.09  ? 175  LEU A CA  1 
ATOM 1250 C C   . LEU A 1 175  ? 161.005 177.157 195.031 1.00 13.21  ? 175  LEU A C   1 
ATOM 1251 O O   . LEU A 1 175  ? 161.855 176.985 194.142 1.00 13.14  ? 175  LEU A O   1 
ATOM 1252 C CB  . LEU A 1 175  ? 158.790 175.973 195.084 1.00 10.39  ? 175  LEU A CB  1 
ATOM 1253 C CG  . LEU A 1 175  ? 157.966 174.764 195.526 1.00 15.19  ? 175  LEU A CG  1 
ATOM 1254 C CD1 . LEU A 1 175  ? 156.480 175.080 195.513 1.00 15.03  ? 175  LEU A CD1 1 
ATOM 1255 C CD2 . LEU A 1 175  ? 158.275 173.573 194.645 1.00 12.54  ? 175  LEU A CD2 1 
ATOM 1256 N N   . GLY A 1 176  ? 160.740 178.363 195.538 1.00 16.85  ? 176  GLY A N   1 
ATOM 1257 C CA  . GLY A 1 176  ? 161.468 179.522 195.064 1.00 6.10   ? 176  GLY A CA  1 
ATOM 1258 C C   . GLY A 1 176  ? 162.954 179.422 195.330 1.00 5.43   ? 176  GLY A C   1 
ATOM 1259 O O   . GLY A 1 176  ? 163.763 179.742 194.462 1.00 11.06  ? 176  GLY A O   1 
ATOM 1260 N N   . TRP A 1 177  ? 163.337 178.963 196.524 1.00 6.34   ? 177  TRP A N   1 
ATOM 1261 C CA  . TRP A 1 177  ? 164.756 178.860 196.831 1.00 5.64   ? 177  TRP A CA  1 
ATOM 1262 C C   . TRP A 1 177  ? 165.429 177.765 196.018 1.00 7.48   ? 177  TRP A C   1 
ATOM 1263 O O   . TRP A 1 177  ? 166.597 177.904 195.659 1.00 14.61  ? 177  TRP A O   1 
ATOM 1264 C CB  . TRP A 1 177  ? 164.974 178.620 198.325 1.00 4.79   ? 177  TRP A CB  1 
ATOM 1265 C CG  . TRP A 1 177  ? 166.405 178.302 198.671 1.00 6.98   ? 177  TRP A CG  1 
ATOM 1266 C CD1 . TRP A 1 177  ? 166.844 177.293 199.474 1.00 8.74   ? 177  TRP A CD1 1 
ATOM 1267 C CD2 . TRP A 1 177  ? 167.580 179.005 198.234 1.00 8.67   ? 177  TRP A CD2 1 
ATOM 1268 N NE1 . TRP A 1 177  ? 168.214 177.314 199.558 1.00 9.56   ? 177  TRP A NE1 1 
ATOM 1269 C CE2 . TRP A 1 177  ? 168.690 178.356 198.806 1.00 11.12  ? 177  TRP A CE2 1 
ATOM 1270 C CE3 . TRP A 1 177  ? 167.800 180.116 197.411 1.00 3.97   ? 177  TRP A CE3 1 
ATOM 1271 C CZ2 . TRP A 1 177  ? 169.997 178.779 198.583 1.00 13.87  ? 177  TRP A CZ2 1 
ATOM 1272 C CZ3 . TRP A 1 177  ? 169.097 180.532 197.190 1.00 3.75   ? 177  TRP A CZ3 1 
ATOM 1273 C CH2 . TRP A 1 177  ? 170.179 179.866 197.775 1.00 9.29   ? 177  TRP A CH2 1 
ATOM 1274 N N   . ALA A 1 178  ? 164.721 176.678 195.707 1.00 2.92   ? 178  ALA A N   1 
ATOM 1275 C CA  . ALA A 1 178  ? 165.286 175.674 194.813 1.00 0.00   ? 178  ALA A CA  1 
ATOM 1276 C C   . ALA A 1 178  ? 165.569 176.272 193.443 1.00 9.58   ? 178  ALA A C   1 
ATOM 1277 O O   . ALA A 1 178  ? 166.651 176.072 192.874 1.00 22.35  ? 178  ALA A O   1 
ATOM 1278 C CB  . ALA A 1 178  ? 164.338 174.481 194.693 1.00 4.08   ? 178  ALA A CB  1 
ATOM 1279 N N   . ALA A 1 179  ? 164.609 177.032 192.906 1.00 11.41  ? 179  ALA A N   1 
ATOM 1280 C CA  . ALA A 1 179  ? 164.820 177.661 191.605 1.00 2.50   ? 179  ALA A CA  1 
ATOM 1281 C C   . ALA A 1 179  ? 165.978 178.656 191.647 1.00 0.00   ? 179  ALA A C   1 
ATOM 1282 O O   . ALA A 1 179  ? 166.842 178.654 190.759 1.00 1.20   ? 179  ALA A O   1 
ATOM 1283 C CB  . ALA A 1 179  ? 163.536 178.347 191.141 1.00 5.72   ? 179  ALA A CB  1 
ATOM 1284 N N   . ILE A 1 180  ? 166.017 179.505 192.678 1.00 0.59   ? 180  ILE A N   1 
ATOM 1285 C CA  . ILE A 1 180  ? 167.083 180.498 192.798 1.00 5.35   ? 180  ILE A CA  1 
ATOM 1286 C C   . ILE A 1 180  ? 168.435 179.823 192.961 1.00 10.29  ? 180  ILE A C   1 
ATOM 1287 O O   . ILE A 1 180  ? 169.429 180.258 192.375 1.00 16.71  ? 180  ILE A O   1 
ATOM 1288 C CB  . ILE A 1 180  ? 166.798 181.475 193.955 1.00 1.23   ? 180  ILE A CB  1 
ATOM 1289 C CG1 . ILE A 1 180  ? 165.388 182.048 193.855 1.00 0.00   ? 180  ILE A CG1 1 
ATOM 1290 C CG2 . ILE A 1 180  ? 167.824 182.593 193.982 1.00 3.04   ? 180  ILE A CG2 1 
ATOM 1291 C CD1 . ILE A 1 180  ? 165.070 183.047 194.929 1.00 3.47   ? 180  ILE A CD1 1 
ATOM 1292 N N   . ARG A 1 181  ? 168.505 178.764 193.770 1.00 5.10   ? 181  ARG A N   1 
ATOM 1293 C CA  . ARG A 1 181  ? 169.770 178.066 193.958 1.00 1.98   ? 181  ARG A CA  1 
ATOM 1294 C C   . ARG A 1 181  ? 170.248 177.423 192.666 1.00 6.77   ? 181  ARG A C   1 
ATOM 1295 O O   . ARG A 1 181  ? 171.443 177.466 192.354 1.00 14.35  ? 181  ARG A O   1 
ATOM 1296 C CB  . ARG A 1 181  ? 169.644 177.012 195.055 1.00 4.42   ? 181  ARG A CB  1 
ATOM 1297 C CG  . ARG A 1 181  ? 170.994 176.517 195.507 1.00 10.98  ? 181  ARG A CG  1 
ATOM 1298 C CD  . ARG A 1 181  ? 170.930 175.552 196.664 1.00 9.38   ? 181  ARG A CD  1 
ATOM 1299 N NE  . ARG A 1 181  ? 172.282 175.267 197.123 1.00 14.63  ? 181  ARG A NE  1 
ATOM 1300 C CZ  . ARG A 1 181  ? 172.922 174.131 196.891 1.00 18.12  ? 181  ARG A CZ  1 
ATOM 1301 N NH1 . ARG A 1 181  ? 172.337 173.124 196.265 1.00 14.10  ? 181  ARG A NH1 1 
ATOM 1302 N NH2 . ARG A 1 181  ? 174.186 174.007 197.284 1.00 14.90  ? 181  ARG A NH2 1 
ATOM 1303 N N   . LYS A 1 182  ? 169.337 176.816 191.904 1.00 3.52   ? 182  LYS A N   1 
ATOM 1304 C CA  . LYS A 1 182  ? 169.734 176.240 190.624 1.00 0.42   ? 182  LYS A CA  1 
ATOM 1305 C C   . LYS A 1 182  ? 170.283 177.317 189.694 1.00 13.38  ? 182  LYS A C   1 
ATOM 1306 O O   . LYS A 1 182  ? 171.393 177.189 189.157 1.00 14.85  ? 182  LYS A O   1 
ATOM 1307 C CB  . LYS A 1 182  ? 168.546 175.516 189.992 1.00 0.00   ? 182  LYS A CB  1 
ATOM 1308 C CG  . LYS A 1 182  ? 168.913 174.566 188.871 1.00 3.99   ? 182  LYS A CG  1 
ATOM 1309 C CD  . LYS A 1 182  ? 167.676 173.877 188.321 1.00 5.72   ? 182  LYS A CD  1 
ATOM 1310 C CE  . LYS A 1 182  ? 168.030 172.909 187.206 1.00 12.51  ? 182  LYS A CE  1 
ATOM 1311 N NZ  . LYS A 1 182  ? 168.885 171.791 187.690 1.00 18.01  ? 182  LYS A NZ  1 
ATOM 1312 N N   . CYS A 1 183  ? 169.536 178.413 189.530 1.00 9.06   ? 183  CYS A N   1 
ATOM 1313 C CA  . CYS A 1 183  ? 169.990 179.481 188.644 1.00 0.64   ? 183  CYS A CA  1 
ATOM 1314 C C   . CYS A 1 183  ? 171.286 180.117 189.134 1.00 7.44   ? 183  CYS A C   1 
ATOM 1315 O O   . CYS A 1 183  ? 172.092 180.580 188.321 1.00 15.62  ? 183  CYS A O   1 
ATOM 1316 C CB  . CYS A 1 183  ? 168.903 180.544 188.491 1.00 8.46   ? 183  CYS A CB  1 
ATOM 1317 S SG  . CYS A 1 183  ? 167.283 179.904 188.022 1.00 29.24  ? 183  CYS A SG  1 
ATOM 1318 N N   . ALA A 1 184  ? 171.507 180.149 190.450 1.00 0.09   ? 184  ALA A N   1 
ATOM 1319 C CA  . ALA A 1 184  ? 172.716 180.748 190.998 1.00 0.19   ? 184  ALA A CA  1 
ATOM 1320 C C   . ALA A 1 184  ? 173.930 179.847 190.830 1.00 6.81   ? 184  ALA A C   1 
ATOM 1321 O O   . ALA A 1 184  ? 175.038 180.348 190.612 1.00 11.77  ? 184  ALA A O   1 
ATOM 1322 C CB  . ALA A 1 184  ? 172.512 181.082 192.473 1.00 0.54   ? 184  ALA A CB  1 
ATOM 1323 N N   . LYS A 1 185  ? 173.751 178.530 190.940 1.00 12.20  ? 185  LYS A N   1 
ATOM 1324 C CA  . LYS A 1 185  ? 174.832 177.621 190.577 1.00 6.66   ? 185  LYS A CA  1 
ATOM 1325 C C   . LYS A 1 185  ? 175.170 177.749 189.099 1.00 9.69   ? 185  LYS A C   1 
ATOM 1326 O O   . LYS A 1 185  ? 176.347 177.723 188.720 1.00 18.02  ? 185  LYS A O   1 
ATOM 1327 C CB  . LYS A 1 185  ? 174.466 176.179 190.925 1.00 9.09   ? 185  LYS A CB  1 
ATOM 1328 C CG  . LYS A 1 185  ? 174.143 175.962 192.389 1.00 11.81  ? 185  LYS A CG  1 
ATOM 1329 C CD  . LYS A 1 185  ? 175.368 176.196 193.252 1.00 9.63   ? 185  LYS A CD  1 
ATOM 1330 C CE  . LYS A 1 185  ? 175.212 175.552 194.615 1.00 16.25  ? 185  LYS A CE  1 
ATOM 1331 N NZ  . LYS A 1 185  ? 176.465 175.624 195.415 1.00 16.96  ? 185  LYS A NZ  1 
ATOM 1332 N N   . LEU A 1 186  ? 174.151 177.890 188.246 1.00 13.01  ? 186  LEU A N   1 
ATOM 1333 C CA  . LEU A 1 186  ? 174.428 178.175 186.840 1.00 5.43   ? 186  LEU A CA  1 
ATOM 1334 C C   . LEU A 1 186  ? 175.091 179.539 186.667 1.00 8.14   ? 186  LEU A C   1 
ATOM 1335 O O   . LEU A 1 186  ? 175.985 179.697 185.828 1.00 9.84   ? 186  LEU A O   1 
ATOM 1336 C CB  . LEU A 1 186  ? 173.147 178.089 186.008 1.00 4.43   ? 186  LEU A CB  1 
ATOM 1337 C CG  . LEU A 1 186  ? 172.676 176.713 185.520 1.00 6.28   ? 186  LEU A CG  1 
ATOM 1338 C CD1 . LEU A 1 186  ? 173.700 176.128 184.564 1.00 15.90  ? 186  LEU A CD1 1 
ATOM 1339 C CD2 . LEU A 1 186  ? 172.394 175.740 186.648 1.00 4.44   ? 186  LEU A CD2 1 
ATOM 1340 N N   . ALA A 1 187  ? 174.671 180.535 187.445 1.00 7.30   ? 187  ALA A N   1 
ATOM 1341 C CA  . ALA A 1 187  ? 175.200 181.888 187.325 1.00 4.41   ? 187  ALA A CA  1 
ATOM 1342 C C   . ALA A 1 187  ? 176.455 182.123 188.154 1.00 11.17  ? 187  ALA A C   1 
ATOM 1343 O O   . ALA A 1 187  ? 176.999 183.232 188.117 1.00 15.23  ? 187  ALA A O   1 
ATOM 1344 C CB  . ALA A 1 187  ? 174.133 182.913 187.721 1.00 0.00   ? 187  ALA A CB  1 
ATOM 1345 N N   . ALA A 1 188  ? 176.922 181.116 188.896 1.00 8.61   ? 188  ALA A N   1 
ATOM 1346 C CA  . ALA A 1 188  ? 178.115 181.230 189.740 1.00 1.51   ? 188  ALA A CA  1 
ATOM 1347 C C   . ALA A 1 188  ? 177.983 182.371 190.746 1.00 8.96   ? 188  ALA A C   1 
ATOM 1348 O O   . ALA A 1 188  ? 178.912 183.156 190.950 1.00 14.02  ? 188  ALA A O   1 
ATOM 1349 C CB  . ALA A 1 188  ? 179.381 181.391 188.896 1.00 4.04   ? 188  ALA A CB  1 
ATOM 1350 N N   . ALA A 1 189  ? 176.819 182.463 191.381 1.00 10.80  ? 189  ALA A N   1 
ATOM 1351 C CA  . ALA A 1 189  ? 176.556 183.505 192.359 1.00 3.93   ? 189  ALA A CA  1 
ATOM 1352 C C   . ALA A 1 189  ? 177.098 183.109 193.732 1.00 15.49  ? 189  ALA A C   1 
ATOM 1353 O O   . ALA A 1 189  ? 177.518 181.973 193.964 1.00 18.50  ? 189  ALA A O   1 
ATOM 1354 C CB  . ALA A 1 189  ? 175.059 183.791 192.442 1.00 5.35   ? 189  ALA A CB  1 
ATOM 1355 N N   . LYS A 1 190  ? 177.083 184.070 194.652 1.00 17.38  ? 190  LYS A N   1 
ATOM 1356 C CA  . LYS A 1 190  ? 177.485 183.846 196.033 1.00 16.18  ? 190  LYS A CA  1 
ATOM 1357 C C   . LYS A 1 190  ? 176.270 183.903 196.947 1.00 13.90  ? 190  LYS A C   1 
ATOM 1358 O O   . LYS A 1 190  ? 175.374 184.730 196.756 1.00 14.22  ? 190  LYS A O   1 
ATOM 1359 C CB  . LYS A 1 190  ? 178.519 184.875 196.503 1.00 16.41  ? 190  LYS A CB  1 
ATOM 1360 C CG  . LYS A 1 190  ? 179.959 184.567 196.121 1.00 19.65  ? 190  LYS A CG  1 
ATOM 1361 C CD  . LYS A 1 190  ? 180.215 184.808 194.651 1.00 22.69  ? 190  LYS A CD  1 
ATOM 1362 C CE  . LYS A 1 190  ? 180.163 186.292 194.346 1.00 25.42  ? 190  LYS A CE  1 
ATOM 1363 N NZ  . LYS A 1 190  ? 180.473 186.568 192.925 1.00 22.12  ? 190  LYS A NZ  1 
ATOM 1364 N N   . PHE A 1 191  ? 176.245 183.019 197.937 1.00 16.65  ? 191  PHE A N   1 
ATOM 1365 C CA  . PHE A 1 191  ? 175.206 183.000 198.952 1.00 15.32  ? 191  PHE A CA  1 
ATOM 1366 C C   . PHE A 1 191  ? 175.768 183.508 200.272 1.00 18.71  ? 191  PHE A C   1 
ATOM 1367 O O   . PHE A 1 191  ? 176.976 183.459 200.516 1.00 25.90  ? 191  PHE A O   1 
ATOM 1368 C CB  . PHE A 1 191  ? 174.641 181.588 199.137 1.00 13.87  ? 191  PHE A CB  1 
ATOM 1369 C CG  . PHE A 1 191  ? 174.369 180.869 197.852 1.00 13.33  ? 191  PHE A CG  1 
ATOM 1370 C CD1 . PHE A 1 191  ? 173.290 181.217 197.063 1.00 9.56   ? 191  PHE A CD1 1 
ATOM 1371 C CD2 . PHE A 1 191  ? 175.190 179.836 197.437 1.00 19.88  ? 191  PHE A CD2 1 
ATOM 1372 C CE1 . PHE A 1 191  ? 173.038 180.551 195.883 1.00 14.12  ? 191  PHE A CE1 1 
ATOM 1373 C CE2 . PHE A 1 191  ? 174.942 179.168 196.257 1.00 17.37  ? 191  PHE A CE2 1 
ATOM 1374 C CZ  . PHE A 1 191  ? 173.866 179.526 195.479 1.00 15.02  ? 191  PHE A CZ  1 
ATOM 1375 N N   . ASP A 1 192  ? 174.878 184.000 201.128 1.00 20.01  ? 192  ASP A N   1 
ATOM 1376 C CA  . ASP A 1 192  ? 175.282 184.428 202.460 1.00 19.58  ? 192  ASP A CA  1 
ATOM 1377 C C   . ASP A 1 192  ? 175.423 183.193 203.349 1.00 18.73  ? 192  ASP A C   1 
ATOM 1378 O O   . ASP A 1 192  ? 175.366 182.053 202.880 1.00 20.56  ? 192  ASP A O   1 
ATOM 1379 C CB  . ASP A 1 192  ? 174.292 185.442 203.028 1.00 18.67  ? 192  ASP A CB  1 
ATOM 1380 C CG  . ASP A 1 192  ? 172.869 184.939 203.009 1.00 21.70  ? 192  ASP A CG  1 
ATOM 1381 O OD1 . ASP A 1 192  ? 172.569 184.059 202.183 1.00 27.59  ? 192  ASP A OD1 1 
ATOM 1382 O OD2 . ASP A 1 192  ? 172.053 185.416 203.825 1.00 19.64  ? 192  ASP A OD2 1 
ATOM 1383 N N   . ASP A 1 193  ? 175.599 183.410 204.654 1.00 26.15  ? 193  ASP A N   1 
ATOM 1384 C CA  . ASP A 1 193  ? 175.869 182.296 205.557 1.00 27.35  ? 193  ASP A CA  1 
ATOM 1385 C C   . ASP A 1 193  ? 174.723 181.292 205.571 1.00 24.82  ? 193  ASP A C   1 
ATOM 1386 O O   . ASP A 1 193  ? 174.955 180.078 205.583 1.00 23.96  ? 193  ASP A O   1 
ATOM 1387 C CB  . ASP A 1 193  ? 176.151 182.820 206.968 1.00 25.09  ? 193  ASP A CB  1 
ATOM 1388 C CG  . ASP A 1 193  ? 174.963 183.550 207.579 1.00 30.18  ? 193  ASP A CG  1 
ATOM 1389 O OD1 . ASP A 1 193  ? 173.922 183.696 206.905 1.00 30.87  ? 193  ASP A OD1 1 
ATOM 1390 O OD2 . ASP A 1 193  ? 175.074 183.982 208.746 1.00 33.81  ? 193  ASP A OD2 1 
ATOM 1391 N N   . TYR A 1 194  ? 173.480 181.775 205.569 1.00 23.24  ? 194  TYR A N   1 
ATOM 1392 C CA  . TYR A 1 194  ? 172.350 180.864 205.686 1.00 16.24  ? 194  TYR A CA  1 
ATOM 1393 C C   . TYR A 1 194  ? 172.127 180.070 204.403 1.00 20.46  ? 194  TYR A C   1 
ATOM 1394 O O   . TYR A 1 194  ? 171.879 178.861 204.459 1.00 26.27  ? 194  TYR A O   1 
ATOM 1395 C CB  . TYR A 1 194  ? 171.088 181.635 206.066 1.00 20.52  ? 194  TYR A CB  1 
ATOM 1396 C CG  . TYR A 1 194  ? 169.857 180.765 206.131 1.00 27.71  ? 194  TYR A CG  1 
ATOM 1397 C CD1 . TYR A 1 194  ? 169.740 179.776 207.097 1.00 28.36  ? 194  TYR A CD1 1 
ATOM 1398 C CD2 . TYR A 1 194  ? 168.814 180.929 205.231 1.00 21.61  ? 194  TYR A CD2 1 
ATOM 1399 C CE1 . TYR A 1 194  ? 168.623 178.975 207.166 1.00 23.82  ? 194  TYR A CE1 1 
ATOM 1400 C CE2 . TYR A 1 194  ? 167.691 180.131 205.293 1.00 21.19  ? 194  TYR A CE2 1 
ATOM 1401 C CZ  . TYR A 1 194  ? 167.602 179.155 206.263 1.00 23.76  ? 194  TYR A CZ  1 
ATOM 1402 O OH  . TYR A 1 194  ? 166.491 178.352 206.340 1.00 26.28  ? 194  TYR A OH  1 
ATOM 1403 N N   . LEU A 1 195  ? 172.216 180.724 203.242 1.00 22.79  ? 195  LEU A N   1 
ATOM 1404 C CA  . LEU A 1 195  ? 171.925 180.031 201.990 1.00 14.29  ? 195  LEU A CA  1 
ATOM 1405 C C   . LEU A 1 195  ? 173.062 179.111 201.555 1.00 18.62  ? 195  LEU A C   1 
ATOM 1406 O O   . LEU A 1 195  ? 172.819 178.154 200.811 1.00 25.20  ? 195  LEU A O   1 
ATOM 1407 C CB  . LEU A 1 195  ? 171.593 181.034 200.885 1.00 18.02  ? 195  LEU A CB  1 
ATOM 1408 C CG  . LEU A 1 195  ? 170.487 182.060 201.141 1.00 16.14  ? 195  LEU A CG  1 
ATOM 1409 C CD1 . LEU A 1 195  ? 170.406 183.054 199.992 1.00 16.33  ? 195  LEU A CD1 1 
ATOM 1410 C CD2 . LEU A 1 195  ? 169.150 181.375 201.350 1.00 11.22  ? 195  LEU A CD2 1 
ATOM 1411 N N   . GLU A 1 196  ? 174.301 179.371 201.989 1.00 20.36  ? 196  GLU A N   1 
ATOM 1412 C CA  . GLU A 1 196  ? 175.376 178.417 201.720 1.00 22.62  ? 196  GLU A CA  1 
ATOM 1413 C C   . GLU A 1 196  ? 175.087 177.068 202.366 1.00 28.39  ? 196  GLU A C   1 
ATOM 1414 O O   . GLU A 1 196  ? 175.275 176.022 201.736 1.00 29.87  ? 196  GLU A O   1 
ATOM 1415 C CB  . GLU A 1 196  ? 176.720 178.966 202.213 1.00 25.24  ? 196  GLU A CB  1 
ATOM 1416 C CG  . GLU A 1 196  ? 177.948 178.072 201.955 1.00 25.35  ? 196  GLU A CG  1 
ATOM 1417 C CD  . GLU A 1 196  ? 178.257 177.895 200.481 1.00 28.86  ? 196  GLU A CD  1 
ATOM 1418 O OE1 . GLU A 1 196  ? 177.893 178.785 199.688 1.00 29.17  ? 196  GLU A OE1 1 
ATOM 1419 O OE2 . GLU A 1 196  ? 178.851 176.858 200.113 1.00 31.92  ? 196  GLU A OE2 1 
ATOM 1420 N N   . LYS A 1 197  ? 174.623 177.066 203.616 1.00 25.96  ? 197  LYS A N   1 
ATOM 1421 C CA  . LYS A 1 197  ? 174.415 175.816 204.335 1.00 25.30  ? 197  LYS A CA  1 
ATOM 1422 C C   . LYS A 1 197  ? 173.006 175.260 204.181 1.00 24.28  ? 197  LYS A C   1 
ATOM 1423 O O   . LYS A 1 197  ? 172.736 174.162 204.678 1.00 34.44  ? 197  LYS A O   1 
ATOM 1424 C CB  . LYS A 1 197  ? 174.728 175.986 205.826 1.00 26.19  ? 197  LYS A CB  1 
ATOM 1425 C CG  . LYS A 1 197  ? 173.818 176.944 206.576 1.00 26.24  ? 197  LYS A CG  1 
ATOM 1426 C CD  . LYS A 1 197  ? 174.265 177.066 208.026 1.00 24.11  ? 197  LYS A CD  1 
ATOM 1427 C CE  . LYS A 1 197  ? 173.366 177.992 208.827 1.00 26.96  ? 197  LYS A CE  1 
ATOM 1428 N NZ  . LYS A 1 197  ? 173.466 179.407 208.387 1.00 35.07  ? 197  LYS A NZ  1 
ATOM 1429 N N   . THR A 1 198  ? 172.107 175.976 203.515 1.00 15.12  ? 198  THR A N   1 
ATOM 1430 C CA  . THR A 1 198  ? 170.747 175.507 203.286 1.00 17.07  ? 198  THR A CA  1 
ATOM 1431 C C   . THR A 1 198  ? 170.628 175.010 201.855 1.00 19.08  ? 198  THR A C   1 
ATOM 1432 O O   . THR A 1 198  ? 170.977 175.727 200.912 1.00 24.96  ? 198  THR A O   1 
ATOM 1433 C CB  . THR A 1 198  ? 169.722 176.609 203.548 1.00 16.92  ? 198  THR A CB  1 
ATOM 1434 O OG1 . THR A 1 198  ? 169.824 177.045 204.908 1.00 24.26  ? 198  THR A OG1 1 
ATOM 1435 C CG2 . THR A 1 198  ? 168.325 176.083 203.299 1.00 13.42  ? 198  THR A CG2 1 
ATOM 1436 N N   . HIS A 1 199  ? 170.136 173.786 201.699 1.00 19.80  ? 199  HIS A N   1 
ATOM 1437 C CA  . HIS A 1 199  ? 170.083 173.114 200.411 1.00 9.58   ? 199  HIS A CA  1 
ATOM 1438 C C   . HIS A 1 199  ? 168.647 172.701 200.133 1.00 11.63  ? 199  HIS A C   1 
ATOM 1439 O O   . HIS A 1 199  ? 168.011 172.061 200.975 1.00 18.69  ? 199  HIS A O   1 
ATOM 1440 C CB  . HIS A 1 199  ? 170.997 171.888 200.409 1.00 11.17  ? 199  HIS A CB  1 
ATOM 1441 C CG  . HIS A 1 199  ? 172.445 172.213 200.595 1.00 18.08  ? 199  HIS A CG  1 
ATOM 1442 N ND1 . HIS A 1 199  ? 173.173 172.929 199.671 1.00 16.62  ? 199  HIS A ND1 1 
ATOM 1443 C CD2 . HIS A 1 199  ? 173.300 171.929 201.606 1.00 23.39  ? 199  HIS A CD2 1 
ATOM 1444 C CE1 . HIS A 1 199  ? 174.414 173.066 200.100 1.00 18.69  ? 199  HIS A CE1 1 
ATOM 1445 N NE2 . HIS A 1 199  ? 174.518 172.468 201.273 1.00 20.66  ? 199  HIS A NE2 1 
ATOM 1446 N N   . VAL A 1 200  ? 168.132 173.078 198.967 1.00 5.21   ? 200  VAL A N   1 
ATOM 1447 C CA  . VAL A 1 200  ? 166.813 172.648 198.521 1.00 2.85   ? 200  VAL A CA  1 
ATOM 1448 C C   . VAL A 1 200  ? 166.924 172.211 197.069 1.00 5.69   ? 200  VAL A C   1 
ATOM 1449 O O   . VAL A 1 200  ? 167.355 172.992 196.213 1.00 11.40  ? 200  VAL A O   1 
ATOM 1450 C CB  . VAL A 1 200  ? 165.753 173.755 198.678 1.00 1.25   ? 200  VAL A CB  1 
ATOM 1451 C CG1 . VAL A 1 200  ? 164.442 173.309 198.069 1.00 5.54   ? 200  VAL A CG1 1 
ATOM 1452 C CG2 . VAL A 1 200  ? 165.559 174.101 200.141 1.00 6.12   ? 200  VAL A CG2 1 
ATOM 1453 N N   . ILE A 1 201  ? 166.537 170.969 196.793 1.00 3.80   ? 201  ILE A N   1 
ATOM 1454 C CA  . ILE A 1 201  ? 166.664 170.375 195.469 1.00 3.46   ? 201  ILE A CA  1 
ATOM 1455 C C   . ILE A 1 201  ? 165.301 169.856 195.037 1.00 4.54   ? 201  ILE A C   1 
ATOM 1456 O O   . ILE A 1 201  ? 164.611 169.183 195.808 1.00 17.48  ? 201  ILE A O   1 
ATOM 1457 C CB  . ILE A 1 201  ? 167.705 169.233 195.446 1.00 4.34   ? 201  ILE A CB  1 
ATOM 1458 C CG1 . ILE A 1 201  ? 169.103 169.750 195.798 1.00 9.94   ? 201  ILE A CG1 1 
ATOM 1459 C CG2 . ILE A 1 201  ? 167.729 168.554 194.087 1.00 4.97   ? 201  ILE A CG2 1 
ATOM 1460 C CD1 . ILE A 1 201  ? 169.425 169.715 197.279 1.00 9.69   ? 201  ILE A CD1 1 
ATOM 1461 N N   . LYS A 1 202  ? 164.908 170.178 193.806 1.00 0.00   ? 202  LYS A N   1 
ATOM 1462 C CA  . LYS A 1 202  ? 163.719 169.607 193.178 1.00 1.00   ? 202  LYS A CA  1 
ATOM 1463 C C   . LYS A 1 202  ? 164.152 169.024 191.841 1.00 9.03   ? 202  LYS A C   1 
ATOM 1464 O O   . LYS A 1 202  ? 164.147 169.715 190.813 1.00 13.39  ? 202  LYS A O   1 
ATOM 1465 C CB  . LYS A 1 202  ? 162.605 170.644 193.018 1.00 8.88   ? 202  LYS A CB  1 
ATOM 1466 C CG  . LYS A 1 202  ? 161.308 170.068 192.469 1.00 7.37   ? 202  LYS A CG  1 
ATOM 1467 C CD  . LYS A 1 202  ? 160.203 171.104 192.404 1.00 9.90   ? 202  LYS A CD  1 
ATOM 1468 C CE  . LYS A 1 202  ? 158.932 170.490 191.845 1.00 14.33  ? 202  LYS A CE  1 
ATOM 1469 N NZ  . LYS A 1 202  ? 157.819 171.473 191.761 1.00 9.69   ? 202  LYS A NZ  1 
ATOM 1470 N N   . PRO A 1 203  ? 164.570 167.759 191.825 1.00 11.59  ? 203  PRO A N   1 
ATOM 1471 C CA  . PRO A 1 203  ? 164.979 167.131 190.564 1.00 5.78   ? 203  PRO A CA  1 
ATOM 1472 C C   . PRO A 1 203  ? 163.787 166.905 189.646 1.00 11.53  ? 203  PRO A C   1 
ATOM 1473 O O   . PRO A 1 203  ? 162.735 166.427 190.075 1.00 20.35  ? 203  PRO A O   1 
ATOM 1474 C CB  . PRO A 1 203  ? 165.598 165.812 191.034 1.00 6.11   ? 203  PRO A CB  1 
ATOM 1475 C CG  . PRO A 1 203  ? 164.733 165.481 192.218 1.00 5.99   ? 203  PRO A CG  1 
ATOM 1476 C CD  . PRO A 1 203  ? 164.724 166.810 192.942 1.00 7.33   ? 203  PRO A CD  1 
ATOM 1477 N N   . THR A 1 204  ? 163.959 167.253 188.374 1.00 6.89   ? 204  THR A N   1 
ATOM 1478 C CA  . THR A 1 204  ? 162.938 167.005 187.367 1.00 9.32   ? 204  THR A CA  1 
ATOM 1479 C C   . THR A 1 204  ? 163.288 165.848 186.443 1.00 10.68  ? 204  THR A C   1 
ATOM 1480 O O   . THR A 1 204  ? 162.421 165.394 185.690 1.00 15.65  ? 204  THR A O   1 
ATOM 1481 C CB  . THR A 1 204  ? 162.692 168.269 186.532 1.00 9.29   ? 204  THR A CB  1 
ATOM 1482 O OG1 . THR A 1 204  ? 163.899 168.640 185.853 1.00 16.77  ? 204  THR A OG1 1 
ATOM 1483 C CG2 . THR A 1 204  ? 162.241 169.415 187.423 1.00 11.49  ? 204  THR A CG2 1 
ATOM 1484 N N   . SER A 1 205  ? 164.526 165.360 186.486 1.00 7.35   ? 205  SER A N   1 
ATOM 1485 C CA  . SER A 1 205  ? 164.950 164.236 185.668 1.00 7.05   ? 205  SER A CA  1 
ATOM 1486 C C   . SER A 1 205  ? 165.774 163.279 186.515 1.00 10.07  ? 205  SER A C   1 
ATOM 1487 O O   . SER A 1 205  ? 166.408 163.679 187.495 1.00 11.79  ? 205  SER A O   1 
ATOM 1488 C CB  . SER A 1 205  ? 165.762 164.697 184.450 1.00 11.36  ? 205  SER A CB  1 
ATOM 1489 O OG  . SER A 1 205  ? 166.992 165.278 184.843 1.00 20.05  ? 205  SER A OG  1 
ATOM 1490 N N   . LEU A 1 206  ? 165.761 162.007 186.123 1.00 9.72   ? 206  LEU A N   1 
ATOM 1491 C CA  . LEU A 1 206  ? 166.449 160.945 186.840 1.00 3.15   ? 206  LEU A CA  1 
ATOM 1492 C C   . LEU A 1 206  ? 167.498 160.286 185.959 1.00 9.80   ? 206  LEU A C   1 
ATOM 1493 O O   . LEU A 1 206  ? 167.355 160.210 184.736 1.00 17.17  ? 206  LEU A O   1 
ATOM 1494 C CB  . LEU A 1 206  ? 165.468 159.876 187.338 1.00 7.42   ? 206  LEU A CB  1 
ATOM 1495 C CG  . LEU A 1 206  ? 164.638 160.214 188.571 1.00 7.70   ? 206  LEU A CG  1 
ATOM 1496 C CD1 . LEU A 1 206  ? 163.780 159.036 188.969 1.00 8.21   ? 206  LEU A CD1 1 
ATOM 1497 C CD2 . LEU A 1 206  ? 165.578 160.567 189.692 1.00 8.04   ? 206  LEU A CD2 1 
ATOM 1498 N N   . SER A 1 207  ? 168.561 159.813 186.604 1.00 11.02  ? 207  SER A N   1 
ATOM 1499 C CA  . SER A 1 207  ? 169.583 158.990 185.973 1.00 12.36  ? 207  SER A CA  1 
ATOM 1500 C C   . SER A 1 207  ? 169.589 157.639 186.672 1.00 14.22  ? 207  SER A C   1 
ATOM 1501 O O   . SER A 1 207  ? 169.728 157.574 187.897 1.00 16.76  ? 207  SER A O   1 
ATOM 1502 C CB  . SER A 1 207  ? 170.959 159.652 186.062 1.00 11.80  ? 207  SER A CB  1 
ATOM 1503 O OG  . SER A 1 207  ? 171.957 158.836 185.479 1.00 18.38  ? 207  SER A OG  1 
ATOM 1504 N N   . LEU A 1 208  ? 169.431 156.569 185.901 1.00 14.23  ? 208  LEU A N   1 
ATOM 1505 C CA  . LEU A 1 208  ? 169.388 155.216 186.445 1.00 14.81  ? 208  LEU A CA  1 
ATOM 1506 C C   . LEU A 1 208  ? 170.758 154.581 186.255 1.00 16.78  ? 208  LEU A C   1 
ATOM 1507 O O   . LEU A 1 208  ? 171.151 154.264 185.129 1.00 22.05  ? 208  LEU A O   1 
ATOM 1508 C CB  . LEU A 1 208  ? 168.303 154.375 185.777 1.00 16.66  ? 208  LEU A CB  1 
ATOM 1509 C CG  . LEU A 1 208  ? 166.881 154.492 186.329 1.00 15.80  ? 208  LEU A CG  1 
ATOM 1510 C CD1 . LEU A 1 208  ? 166.434 155.946 186.374 1.00 14.40  ? 208  LEU A CD1 1 
ATOM 1511 C CD2 . LEU A 1 208  ? 165.902 153.635 185.538 1.00 17.67  ? 208  LEU A CD2 1 
ATOM 1512 N N   . ARG A 1 209  ? 171.481 154.396 187.353 1.00 8.81   ? 209  ARG A N   1 
ATOM 1513 C CA  . ARG A 1 209  ? 172.782 153.746 187.321 1.00 11.83  ? 209  ARG A CA  1 
ATOM 1514 C C   . ARG A 1 209  ? 172.576 152.241 187.429 1.00 19.58  ? 209  ARG A C   1 
ATOM 1515 O O   . ARG A 1 209  ? 171.984 151.760 188.401 1.00 27.46  ? 209  ARG A O   1 
ATOM 1516 C CB  . ARG A 1 209  ? 173.667 154.258 188.455 1.00 16.17  ? 209  ARG A CB  1 
ATOM 1517 C CG  . ARG A 1 209  ? 173.882 155.759 188.437 1.00 17.35  ? 209  ARG A CG  1 
ATOM 1518 C CD  . ARG A 1 209  ? 174.722 156.201 189.620 1.00 20.44  ? 209  ARG A CD  1 
ATOM 1519 N NE  . ARG A 1 209  ? 175.556 157.352 189.301 1.00 24.78  ? 209  ARG A NE  1 
ATOM 1520 C CZ  . ARG A 1 209  ? 176.321 157.986 190.179 1.00 25.70  ? 209  ARG A CZ  1 
ATOM 1521 N NH1 . ARG A 1 209  ? 176.386 157.602 191.443 1.00 21.18  ? 209  ARG A NH1 1 
ATOM 1522 N NH2 . ARG A 1 209  ? 177.038 159.032 189.779 1.00 24.53  ? 209  ARG A NH2 1 
ATOM 1523 N N   . LEU A 1 210  ? 173.057 151.503 186.432 1.00 17.01  ? 210  LEU A N   1 
ATOM 1524 C CA  . LEU A 1 210  ? 172.868 150.061 186.358 1.00 14.59  ? 210  LEU A CA  1 
ATOM 1525 C C   . LEU A 1 210  ? 174.218 149.368 186.445 1.00 16.65  ? 210  LEU A C   1 
ATOM 1526 O O   . LEU A 1 210  ? 175.181 149.790 185.797 1.00 26.27  ? 210  LEU A O   1 
ATOM 1527 C CB  . LEU A 1 210  ? 172.152 149.665 185.064 1.00 15.95  ? 210  LEU A CB  1 
ATOM 1528 C CG  . LEU A 1 210  ? 170.838 150.387 184.763 1.00 16.42  ? 210  LEU A CG  1 
ATOM 1529 C CD1 . LEU A 1 210  ? 170.547 150.365 183.273 1.00 21.27  ? 210  LEU A CD1 1 
ATOM 1530 C CD2 . LEU A 1 210  ? 169.697 149.762 185.543 1.00 11.71  ? 210  LEU A CD2 1 
ATOM 1531 N N   . ARG A 1 211  ? 174.286 148.313 187.254 1.00 15.82  ? 211  ARG A N   1 
ATOM 1532 C CA  . ARG A 1 211  ? 175.494 147.516 187.402 1.00 18.43  ? 211  ARG A CA  1 
ATOM 1533 C C   . ARG A 1 211  ? 175.119 146.047 187.505 1.00 22.57  ? 211  ARG A C   1 
ATOM 1534 O O   . ARG A 1 211  ? 174.085 145.703 188.082 1.00 27.15  ? 211  ARG A O   1 
ATOM 1535 C CB  . ARG A 1 211  ? 176.299 147.931 188.641 1.00 17.68  ? 211  ARG A CB  1 
ATOM 1536 C CG  . ARG A 1 211  ? 176.947 149.300 188.541 1.00 21.35  ? 211  ARG A CG  1 
ATOM 1537 C CD  . ARG A 1 211  ? 177.138 149.923 189.915 1.00 26.57  ? 211  ARG A CD  1 
ATOM 1538 N NE  . ARG A 1 211  ? 175.967 149.747 190.766 1.00 27.92  ? 211  ARG A NE  1 
ATOM 1539 C CZ  . ARG A 1 211  ? 174.867 150.484 190.691 1.00 25.78  ? 211  ARG A CZ  1 
ATOM 1540 N NH1 . ARG A 1 211  ? 174.748 151.458 189.805 1.00 20.42  ? 211  ARG A NH1 1 
ATOM 1541 N NH2 . ARG A 1 211  ? 173.863 150.238 191.526 1.00 24.02  ? 211  ARG A NH2 1 
ATOM 1542 N N   . LYS A 1 212  ? 175.963 145.187 186.945 1.00 25.46  ? 212  LYS A N   1 
ATOM 1543 C CA  . LYS A 1 212  ? 175.804 143.747 187.073 1.00 24.46  ? 212  LYS A CA  1 
ATOM 1544 C C   . LYS A 1 212  ? 176.569 143.261 188.296 1.00 28.05  ? 212  LYS A C   1 
ATOM 1545 O O   . LYS A 1 212  ? 177.775 143.497 188.414 1.00 28.10  ? 212  LYS A O   1 
ATOM 1546 C CB  . LYS A 1 212  ? 176.304 143.032 185.818 1.00 27.35  ? 212  LYS A CB  1 
ATOM 1547 C CG  . LYS A 1 212  ? 175.482 143.286 184.572 1.00 22.52  ? 212  LYS A CG  1 
ATOM 1548 C CD  . LYS A 1 212  ? 176.032 142.484 183.410 1.00 20.89  ? 212  LYS A CD  1 
ATOM 1549 C CE  . LYS A 1 212  ? 175.279 142.765 182.194 1.00 25.48  ? 212  LYS A CE  1 
ATOM 1550 N NZ  . LYS A 1 212  ? 173.884 142.296 182.176 1.00 27.46  ? 212  LYS A NZ  1 
ATOM 1551 N N   . ALA A 1 213  ? 175.869 142.579 189.198 1.00 35.42  ? 213  ALA A N   1 
ATOM 1552 C CA  . ALA A 1 213  ? 176.450 142.115 190.448 1.00 38.04  ? 213  ALA A CA  1 
ATOM 1553 C C   . ALA A 1 213  ? 176.120 140.644 190.656 1.00 41.11  ? 213  ALA A C   1 
ATOM 1554 O O   . ALA A 1 213  ? 175.157 140.114 190.097 1.00 40.42  ? 213  ALA A O   1 
ATOM 1555 C CB  . ALA A 1 213  ? 175.950 142.941 191.641 1.00 34.36  ? 213  ALA A CB  1 
ATOM 1556 N N   . THR A 1 214  ? 176.944 139.983 191.466 1.00 53.11  ? 214  THR A N   1 
ATOM 1557 C CA  . THR A 1 214  ? 176.766 138.573 191.790 1.00 52.88  ? 214  THR A CA  1 
ATOM 1558 C C   . THR A 1 214  ? 176.615 138.425 193.297 1.00 55.67  ? 214  THR A C   1 
ATOM 1559 O O   . THR A 1 214  ? 177.510 138.813 194.055 1.00 56.13  ? 214  THR A O   1 
ATOM 1560 C CB  . THR A 1 214  ? 177.944 137.735 191.287 1.00 52.42  ? 214  THR A CB  1 
ATOM 1561 O OG1 . THR A 1 214  ? 179.151 138.173 191.923 1.00 53.77  ? 214  THR A OG1 1 
ATOM 1562 C CG2 . THR A 1 214  ? 178.091 137.871 189.778 1.00 52.98  ? 214  THR A CG2 1 
ATOM 1563 N N   . VAL A 1 215  ? 175.484 137.869 193.724 1.00 65.19  ? 215  VAL A N   1 
ATOM 1564 C CA  . VAL A 1 215  ? 175.264 137.526 195.124 1.00 65.40  ? 215  VAL A CA  1 
ATOM 1565 C C   . VAL A 1 215  ? 175.037 136.038 195.329 1.00 66.52  ? 215  VAL A C   1 
ATOM 1566 O O   . VAL A 1 215  ? 175.046 135.577 196.481 1.00 63.40  ? 215  VAL A O   1 
ATOM 1567 C CB  . VAL A 1 215  ? 174.085 138.323 195.724 1.00 62.85  ? 215  VAL A CB  1 
ATOM 1568 C CG1 . VAL A 1 215  ? 174.433 139.800 195.808 1.00 61.97  ? 215  VAL A CG1 1 
ATOM 1569 C CG2 . VAL A 1 215  ? 172.827 138.109 194.898 1.00 61.69  ? 215  VAL A CG2 1 
ATOM 1570 N N   . ALA A 1 216  ? 174.837 135.277 194.260 1.00 73.70  ? 216  ALA A N   1 
ATOM 1571 C CA  . ALA A 1 216  ? 174.621 133.839 194.324 1.00 71.98  ? 216  ALA A CA  1 
ATOM 1572 C C   . ALA A 1 216  ? 175.179 133.237 193.038 1.00 70.74  ? 216  ALA A C   1 
ATOM 1573 O O   . ALA A 1 216  ? 175.980 133.869 192.342 1.00 68.46  ? 216  ALA A O   1 
ATOM 1574 C CB  . ALA A 1 216  ? 173.132 133.525 194.546 1.00 71.22  ? 216  ALA A CB  1 
ATOM 1575 N N   . ASP A 1 217  ? 174.767 132.006 192.729 1.00 72.48  ? 217  ASP A N   1 
ATOM 1576 C CA  . ASP A 1 217  ? 175.197 131.362 191.494 1.00 73.48  ? 217  ASP A CA  1 
ATOM 1577 C C   . ASP A 1 217  ? 174.787 132.165 190.263 1.00 73.23  ? 217  ASP A C   1 
ATOM 1578 O O   . ASP A 1 217  ? 175.500 132.143 189.254 1.00 71.37  ? 217  ASP A O   1 
ATOM 1579 C CB  . ASP A 1 217  ? 174.625 129.940 191.441 1.00 72.66  ? 217  ASP A CB  1 
ATOM 1580 C CG  . ASP A 1 217  ? 175.135 129.131 190.256 1.00 73.91  ? 217  ASP A CG  1 
ATOM 1581 O OD1 . ASP A 1 217  ? 176.306 128.689 190.271 1.00 73.84  ? 217  ASP A OD1 1 
ATOM 1582 O OD2 . ASP A 1 217  ? 174.354 128.930 189.306 1.00 74.48  ? 217  ASP A OD2 1 
ATOM 1583 N N   . THR A 1 218  ? 173.678 132.897 190.337 1.00 69.17  ? 218  THR A N   1 
ATOM 1584 C CA  . THR A 1 218  ? 173.188 133.711 189.234 1.00 69.71  ? 218  THR A CA  1 
ATOM 1585 C C   . THR A 1 218  ? 173.406 135.188 189.537 1.00 69.62  ? 218  THR A C   1 
ATOM 1586 O O   . THR A 1 218  ? 173.216 135.633 190.674 1.00 67.13  ? 218  THR A O   1 
ATOM 1587 C CB  . THR A 1 218  ? 171.701 133.451 188.974 1.00 69.54  ? 218  THR A CB  1 
ATOM 1588 O OG1 . THR A 1 218  ? 170.929 133.940 190.078 1.00 69.67  ? 218  THR A OG1 1 
ATOM 1589 C CG2 . THR A 1 218  ? 171.443 131.962 188.803 1.00 67.84  ? 218  THR A CG2 1 
ATOM 1590 N N   . ALA A 1 219  ? 173.801 135.942 188.515 1.00 51.23  ? 219  ALA A N   1 
ATOM 1591 C CA  . ALA A 1 219  ? 174.089 137.357 188.687 1.00 49.28  ? 219  ALA A CA  1 
ATOM 1592 C C   . ALA A 1 219  ? 172.803 138.161 188.865 1.00 47.14  ? 219  ALA A C   1 
ATOM 1593 O O   . ALA A 1 219  ? 171.703 137.717 188.526 1.00 47.22  ? 219  ALA A O   1 
ATOM 1594 C CB  . ALA A 1 219  ? 174.881 137.893 187.494 1.00 46.72  ? 219  ALA A CB  1 
ATOM 1595 N N   . VAL A 1 220  ? 172.960 139.368 189.412 1.00 37.65  ? 220  VAL A N   1 
ATOM 1596 C CA  . VAL A 1 220  ? 171.853 140.280 189.662 1.00 34.36  ? 220  VAL A CA  1 
ATOM 1597 C C   . VAL A 1 220  ? 172.265 141.668 189.181 1.00 32.77  ? 220  VAL A C   1 
ATOM 1598 O O   . VAL A 1 220  ? 173.449 141.997 189.103 1.00 37.03  ? 220  VAL A O   1 
ATOM 1599 C CB  . VAL A 1 220  ? 171.453 140.301 191.158 1.00 31.45  ? 220  VAL A CB  1 
ATOM 1600 C CG1 . VAL A 1 220  ? 172.582 140.866 192.012 1.00 34.48  ? 220  VAL A CG1 1 
ATOM 1601 C CG2 . VAL A 1 220  ? 170.151 141.058 191.382 1.00 27.53  ? 220  VAL A CG2 1 
ATOM 1602 N N   . ILE A 1 221  ? 171.268 142.483 188.842 1.00 19.31  ? 221  ILE A N   1 
ATOM 1603 C CA  . ILE A 1 221  ? 171.488 143.842 188.362 1.00 15.93  ? 221  ILE A CA  1 
ATOM 1604 C C   . ILE A 1 221  ? 171.089 144.815 189.461 1.00 20.86  ? 221  ILE A C   1 
ATOM 1605 O O   . ILE A 1 221  ? 169.994 144.711 190.026 1.00 24.41  ? 221  ILE A O   1 
ATOM 1606 C CB  . ILE A 1 221  ? 170.702 144.127 187.071 1.00 21.30  ? 221  ILE A CB  1 
ATOM 1607 C CG1 . ILE A 1 221  ? 171.392 143.489 185.870 1.00 24.60  ? 221  ILE A CG1 1 
ATOM 1608 C CG2 . ILE A 1 221  ? 170.553 145.623 186.846 1.00 17.42  ? 221  ILE A CG2 1 
ATOM 1609 C CD1 . ILE A 1 221  ? 170.432 143.101 184.786 1.00 17.54  ? 221  ILE A CD1 1 
ATOM 1610 N N   . GLU A 1 222  ? 171.978 145.755 189.763 1.00 21.38  ? 222  GLU A N   1 
ATOM 1611 C CA  . GLU A 1 222  ? 171.720 146.797 190.745 1.00 15.94  ? 222  GLU A CA  1 
ATOM 1612 C C   . GLU A 1 222  ? 171.290 148.068 190.025 1.00 16.55  ? 222  GLU A C   1 
ATOM 1613 O O   . GLU A 1 222  ? 171.975 148.529 189.107 1.00 19.91  ? 222  GLU A O   1 
ATOM 1614 C CB  . GLU A 1 222  ? 172.965 147.058 191.593 1.00 18.89  ? 222  GLU A CB  1 
ATOM 1615 C CG  . GLU A 1 222  ? 173.589 145.797 192.168 1.00 23.94  ? 222  GLU A CG  1 
ATOM 1616 C CD  . GLU A 1 222  ? 174.657 146.090 193.203 1.00 28.19  ? 222  GLU A CD  1 
ATOM 1617 O OE1 . GLU A 1 222  ? 175.408 147.071 193.022 1.00 30.35  ? 222  GLU A OE1 1 
ATOM 1618 O OE2 . GLU A 1 222  ? 174.746 145.340 194.197 1.00 24.47  ? 222  GLU A OE2 1 
ATOM 1619 N N   . ILE A 1 223  ? 170.155 148.626 190.438 1.00 18.34  ? 223  ILE A N   1 
ATOM 1620 C CA  . ILE A 1 223  ? 169.592 149.829 189.834 1.00 16.84  ? 223  ILE A CA  1 
ATOM 1621 C C   . ILE A 1 223  ? 169.660 150.953 190.859 1.00 16.12  ? 223  ILE A C   1 
ATOM 1622 O O   . ILE A 1 223  ? 169.272 150.769 192.019 1.00 19.37  ? 223  ILE A O   1 
ATOM 1623 C CB  . ILE A 1 223  ? 168.151 149.592 189.345 1.00 15.10  ? 223  ILE A CB  1 
ATOM 1624 C CG1 . ILE A 1 223  ? 167.523 150.898 188.854 1.00 13.93  ? 223  ILE A CG1 1 
ATOM 1625 C CG2 . ILE A 1 223  ? 167.301 148.951 190.434 1.00 16.17  ? 223  ILE A CG2 1 
ATOM 1626 C CD1 . ILE A 1 223  ? 166.277 150.694 188.023 1.00 14.40  ? 223  ILE A CD1 1 
ATOM 1627 N N   . GLU A 1 224  ? 170.169 152.110 190.434 1.00 14.45  ? 224  GLU A N   1 
ATOM 1628 C CA  . GLU A 1 224  ? 170.407 153.209 191.360 1.00 14.47  ? 224  GLU A CA  1 
ATOM 1629 C C   . GLU A 1 224  ? 169.929 154.538 190.783 1.00 14.45  ? 224  GLU A C   1 
ATOM 1630 O O   . GLU A 1 224  ? 170.504 154.999 189.765 1.00 20.03  ? 224  GLU A O   1 
ATOM 1631 C CB  . GLU A 1 224  ? 171.893 153.285 191.713 1.00 12.80  ? 224  GLU A CB  1 
ATOM 1632 C CG  . GLU A 1 224  ? 172.248 154.355 192.725 1.00 16.09  ? 224  GLU A CG  1 
ATOM 1633 C CD  . GLU A 1 224  ? 173.720 154.338 193.084 1.00 23.66  ? 224  GLU A CD  1 
ATOM 1634 O OE1 . GLU A 1 224  ? 174.460 153.501 192.526 1.00 23.30  ? 224  GLU A OE1 1 
ATOM 1635 O OE2 . GLU A 1 224  ? 174.141 155.164 193.920 1.00 24.56  ? 224  GLU A OE2 1 
ATOM 1636 N N   . PRO A 1 225  ? 168.922 155.190 191.373 1.00 9.86   ? 225  PRO A N   1 
ATOM 1637 C CA  . PRO A 1 225  ? 168.547 156.509 190.874 1.00 11.95  ? 225  PRO A CA  1 
ATOM 1638 C C   . PRO A 1 225  ? 169.596 157.569 191.208 1.00 12.84  ? 225  PRO A C   1 
ATOM 1639 O O   . PRO A 1 225  ? 170.372 157.437 192.152 1.00 18.67  ? 225  PRO A O   1 
ATOM 1640 C CB  . PRO A 1 225  ? 167.210 156.806 191.538 1.00 7.05   ? 225  PRO A CB  1 
ATOM 1641 C CG  . PRO A 1 225  ? 167.252 156.037 192.823 1.00 8.33   ? 225  PRO A CG  1 
ATOM 1642 C CD  . PRO A 1 225  ? 168.068 154.797 192.482 1.00 5.06   ? 225  PRO A CD  1 
ATOM 1643 N N   . HIS A 1 226  ? 169.609 158.652 190.415 1.00 8.23   ? 226  HIS A N   1 
ATOM 1644 C CA  . HIS A 1 226  ? 170.554 159.738 190.638 1.00 11.23  ? 226  HIS A CA  1 
ATOM 1645 C C   . HIS A 1 226  ? 169.944 161.056 190.186 1.00 14.38  ? 226  HIS A C   1 
ATOM 1646 O O   . HIS A 1 226  ? 169.136 161.099 189.255 1.00 18.61  ? 226  HIS A O   1 
ATOM 1647 C CB  . HIS A 1 226  ? 171.877 159.485 189.907 1.00 14.10  ? 226  HIS A CB  1 
ATOM 1648 C CG  . HIS A 1 226  ? 173.050 160.176 190.528 1.00 19.70  ? 226  HIS A CG  1 
ATOM 1649 N ND1 . HIS A 1 226  ? 173.633 159.744 191.700 1.00 20.26  ? 226  HIS A ND1 1 
ATOM 1650 C CD2 . HIS A 1 226  ? 173.751 161.267 190.139 1.00 18.40  ? 226  HIS A CD2 1 
ATOM 1651 C CE1 . HIS A 1 226  ? 174.640 160.542 192.007 1.00 19.88  ? 226  HIS A CE1 1 
ATOM 1652 N NE2 . HIS A 1 226  ? 174.733 161.473 191.076 1.00 21.01  ? 226  HIS A NE2 1 
ATOM 1653 N N   . PHE A 1 227  ? 170.345 162.131 190.858 1.00 12.93  ? 227  PHE A N   1 
ATOM 1654 C CA  . PHE A 1 227  ? 169.880 163.483 190.581 1.00 12.72  ? 227  PHE A CA  1 
ATOM 1655 C C   . PHE A 1 227  ? 170.994 164.275 189.912 1.00 19.37  ? 227  PHE A C   1 
ATOM 1656 O O   . PHE A 1 227  ? 172.135 163.820 189.808 1.00 22.21  ? 227  PHE A O   1 
ATOM 1657 C CB  . PHE A 1 227  ? 169.446 164.193 191.870 1.00 17.59  ? 227  PHE A CB  1 
ATOM 1658 C CG  . PHE A 1 227  ? 168.404 163.457 192.663 1.00 13.23  ? 227  PHE A CG  1 
ATOM 1659 C CD1 . PHE A 1 227  ? 167.780 162.328 192.162 1.00 13.31  ? 227  PHE A CD1 1 
ATOM 1660 C CD2 . PHE A 1 227  ? 168.064 163.887 193.931 1.00 3.66   ? 227  PHE A CD2 1 
ATOM 1661 C CE1 . PHE A 1 227  ? 166.839 161.654 192.899 1.00 13.50  ? 227  PHE A CE1 1 
ATOM 1662 C CE2 . PHE A 1 227  ? 167.121 163.216 194.673 1.00 9.36   ? 227  PHE A CE2 1 
ATOM 1663 C CZ  . PHE A 1 227  ? 166.507 162.106 194.150 1.00 16.19  ? 227  PHE A CZ  1 
ATOM 1664 N N   . GLU A 1 228  ? 170.653 165.481 189.455 1.00 25.60  ? 228  GLU A N   1 
ATOM 1665 C CA  . GLU A 1 228  ? 171.684 166.389 188.961 1.00 28.42  ? 228  GLU A CA  1 
ATOM 1666 C C   . GLU A 1 228  ? 172.585 166.850 190.101 1.00 27.78  ? 228  GLU A C   1 
ATOM 1667 O O   . GLU A 1 228  ? 173.814 166.869 189.968 1.00 32.39  ? 228  GLU A O   1 
ATOM 1668 C CB  . GLU A 1 228  ? 171.042 167.583 188.251 1.00 28.36  ? 228  GLU A CB  1 
ATOM 1669 C CG  . GLU A 1 228  ? 172.019 168.477 187.491 1.00 28.89  ? 228  GLU A CG  1 
ATOM 1670 C CD  . GLU A 1 228  ? 172.697 169.506 188.378 1.00 32.27  ? 228  GLU A CD  1 
ATOM 1671 O OE1 . GLU A 1 228  ? 172.087 169.916 189.387 1.00 37.95  ? 228  GLU A OE1 1 
ATOM 1672 O OE2 . GLU A 1 228  ? 173.839 169.903 188.067 1.00 32.45  ? 228  GLU A OE2 1 
ATOM 1673 N N   . ASP A 1 229  ? 171.988 167.221 191.234 1.00 17.69  ? 229  ASP A N   1 
ATOM 1674 C CA  . ASP A 1 229  ? 172.718 167.615 192.440 1.00 19.35  ? 229  ASP A CA  1 
ATOM 1675 C C   . ASP A 1 229  ? 172.047 166.911 193.616 1.00 24.59  ? 229  ASP A C   1 
ATOM 1676 O O   . ASP A 1 229  ? 171.123 167.450 194.230 1.00 27.66  ? 229  ASP A O   1 
ATOM 1677 C CB  . ASP A 1 229  ? 172.729 169.131 192.609 1.00 21.25  ? 229  ASP A CB  1 
ATOM 1678 C CG  . ASP A 1 229  ? 173.748 169.597 193.631 1.00 29.22  ? 229  ASP A CG  1 
ATOM 1679 O OD1 . ASP A 1 229  ? 174.417 168.738 194.242 1.00 32.27  ? 229  ASP A OD1 1 
ATOM 1680 O OD2 . ASP A 1 229  ? 173.882 170.824 193.820 1.00 28.90  ? 229  ASP A OD2 1 
ATOM 1681 N N   . GLN A 1 230  ? 172.520 165.708 193.929 1.00 20.36  ? 230  GLN A N   1 
ATOM 1682 C CA  . GLN A 1 230  ? 171.941 164.826 194.933 1.00 11.95  ? 230  GLN A CA  1 
ATOM 1683 C C   . GLN A 1 230  ? 172.733 164.880 196.233 1.00 17.17  ? 230  GLN A C   1 
ATOM 1684 O O   . GLN A 1 230  ? 173.967 164.806 196.212 1.00 19.36  ? 230  GLN A O   1 
ATOM 1685 C CB  . GLN A 1 230  ? 171.907 163.386 194.422 1.00 16.12  ? 230  GLN A CB  1 
ATOM 1686 C CG  . GLN A 1 230  ? 171.386 162.376 195.423 1.00 14.15  ? 230  GLN A CG  1 
ATOM 1687 C CD  . GLN A 1 230  ? 171.367 160.970 194.865 1.00 15.76  ? 230  GLN A CD  1 
ATOM 1688 O OE1 . GLN A 1 230  ? 170.592 160.660 193.962 1.00 20.58  ? 230  GLN A OE1 1 
ATOM 1689 N NE2 . GLN A 1 230  ? 172.226 160.111 195.398 1.00 22.66  ? 230  GLN A NE2 1 
ATOM 1690 N N   . PRO A 1 231  ? 172.046 165.023 197.367 1.00 12.85  ? 231  PRO A N   1 
ATOM 1691 C CA  . PRO A 1 231  ? 172.738 164.976 198.659 1.00 6.96   ? 231  PRO A CA  1 
ATOM 1692 C C   . PRO A 1 231  ? 173.459 163.650 198.854 1.00 11.18  ? 231  PRO A C   1 
ATOM 1693 O O   . PRO A 1 231  ? 173.039 162.607 198.350 1.00 19.53  ? 231  PRO A O   1 
ATOM 1694 C CB  . PRO A 1 231  ? 171.612 165.150 199.686 1.00 7.91   ? 231  PRO A CB  1 
ATOM 1695 C CG  . PRO A 1 231  ? 170.404 165.562 198.931 1.00 10.07  ? 231  PRO A CG  1 
ATOM 1696 C CD  . PRO A 1 231  ? 170.685 165.573 197.468 1.00 14.40  ? 231  PRO A CD  1 
ATOM 1697 N N   . ALA A 1 232  ? 174.567 163.708 199.597 1.00 17.76  ? 232  ALA A N   1 
ATOM 1698 C CA  . ALA A 1 232  ? 175.403 162.526 199.777 1.00 17.89  ? 232  ALA A CA  1 
ATOM 1699 C C   . ALA A 1 232  ? 174.677 161.418 200.528 1.00 19.15  ? 232  ALA A C   1 
ATOM 1700 O O   . ALA A 1 232  ? 174.987 160.237 200.340 1.00 19.49  ? 232  ALA A O   1 
ATOM 1701 C CB  . ALA A 1 232  ? 176.691 162.903 200.508 1.00 17.53  ? 232  ALA A CB  1 
ATOM 1702 N N   . ASN A 1 233  ? 173.716 161.770 201.382 1.00 15.14  ? 233  ASN A N   1 
ATOM 1703 C CA  . ASN A 1 233  ? 173.005 160.792 202.193 1.00 11.83  ? 233  ASN A CA  1 
ATOM 1704 C C   . ASN A 1 233  ? 171.570 160.564 201.734 1.00 15.07  ? 233  ASN A C   1 
ATOM 1705 O O   . ASN A 1 233  ? 170.797 159.931 202.460 1.00 19.76  ? 233  ASN A O   1 
ATOM 1706 C CB  . ASN A 1 233  ? 173.010 161.216 203.664 1.00 14.35  ? 233  ASN A CB  1 
ATOM 1707 C CG  . ASN A 1 233  ? 174.407 161.338 204.235 1.00 25.38  ? 233  ASN A CG  1 
ATOM 1708 O OD1 . ASN A 1 233  ? 175.323 160.622 203.830 1.00 25.34  ? 233  ASN A OD1 1 
ATOM 1709 N ND2 . ASN A 1 233  ? 174.577 162.246 205.189 1.00 17.26  ? 233  ASN A ND2 1 
ATOM 1710 N N   . TRP A 1 234  ? 171.187 161.065 200.556 1.00 12.70  ? 234  TRP A N   1 
ATOM 1711 C CA  . TRP A 1 234  ? 169.799 160.915 200.128 1.00 12.22  ? 234  TRP A CA  1 
ATOM 1712 C C   . TRP A 1 234  ? 169.458 159.460 199.840 1.00 9.74   ? 234  TRP A C   1 
ATOM 1713 O O   . TRP A 1 234  ? 168.334 159.021 200.105 1.00 13.25  ? 234  TRP A O   1 
ATOM 1714 C CB  . TRP A 1 234  ? 169.506 161.767 198.894 1.00 10.91  ? 234  TRP A CB  1 
ATOM 1715 C CG  . TRP A 1 234  ? 168.143 161.471 198.324 1.00 8.76   ? 234  TRP A CG  1 
ATOM 1716 C CD1 . TRP A 1 234  ? 166.954 162.001 198.731 1.00 5.53   ? 234  TRP A CD1 1 
ATOM 1717 C CD2 . TRP A 1 234  ? 167.828 160.547 197.272 1.00 10.09  ? 234  TRP A CD2 1 
ATOM 1718 N NE1 . TRP A 1 234  ? 165.923 161.480 197.990 1.00 3.86   ? 234  TRP A NE1 1 
ATOM 1719 C CE2 . TRP A 1 234  ? 166.432 160.583 197.089 1.00 7.02   ? 234  TRP A CE2 1 
ATOM 1720 C CE3 . TRP A 1 234  ? 168.592 159.699 196.466 1.00 10.42  ? 234  TRP A CE3 1 
ATOM 1721 C CZ2 . TRP A 1 234  ? 165.784 159.802 196.136 1.00 2.06   ? 234  TRP A CZ2 1 
ATOM 1722 C CZ3 . TRP A 1 234  ? 167.948 158.929 195.517 1.00 7.12   ? 234  TRP A CZ3 1 
ATOM 1723 C CH2 . TRP A 1 234  ? 166.559 158.987 195.357 1.00 8.23   ? 234  TRP A CH2 1 
ATOM 1724 N N   . LEU A 1 235  ? 170.402 158.704 199.276 1.00 2.88   ? 235  LEU A N   1 
ATOM 1725 C CA  . LEU A 1 235  ? 170.112 157.323 198.904 1.00 4.23   ? 235  LEU A CA  1 
ATOM 1726 C C   . LEU A 1 235  ? 169.809 156.467 200.127 1.00 10.38  ? 235  LEU A C   1 
ATOM 1727 O O   . LEU A 1 235  ? 168.929 155.601 200.082 1.00 13.53  ? 235  LEU A O   1 
ATOM 1728 C CB  . LEU A 1 235  ? 171.276 156.732 198.113 1.00 10.00  ? 235  LEU A CB  1 
ATOM 1729 C CG  . LEU A 1 235  ? 170.912 155.554 197.207 1.00 10.93  ? 235  LEU A CG  1 
ATOM 1730 C CD1 . LEU A 1 235  ? 169.695 155.875 196.352 1.00 9.77   ? 235  LEU A CD1 1 
ATOM 1731 C CD2 . LEU A 1 235  ? 172.094 155.166 196.342 1.00 15.31  ? 235  LEU A CD2 1 
ATOM 1732 N N   . GLY A 1 236  ? 170.532 156.686 201.226 1.00 9.20   ? 236  GLY A N   1 
ATOM 1733 C CA  . GLY A 1 236  ? 170.255 155.931 202.437 1.00 6.27   ? 236  GLY A CA  1 
ATOM 1734 C C   . GLY A 1 236  ? 168.865 156.193 202.984 1.00 13.97  ? 236  GLY A C   1 
ATOM 1735 O O   . GLY A 1 236  ? 168.156 155.264 203.379 1.00 18.11  ? 236  GLY A O   1 
ATOM 1736 N N   . SER A 1 237  ? 168.455 157.463 203.012 1.00 9.79   ? 237  SER A N   1 
ATOM 1737 C CA  . SER A 1 237  ? 167.108 157.801 203.460 1.00 4.87   ? 237  SER A CA  1 
ATOM 1738 C C   . SER A 1 237  ? 166.057 157.245 202.509 1.00 6.90   ? 237  SER A C   1 
ATOM 1739 O O   . SER A 1 237  ? 164.995 156.788 202.946 1.00 15.67  ? 237  SER A O   1 
ATOM 1740 C CB  . SER A 1 237  ? 166.967 159.317 203.594 1.00 17.15  ? 237  SER A CB  1 
ATOM 1741 O OG  . SER A 1 237  ? 165.658 159.674 203.998 1.00 23.57  ? 237  SER A OG  1 
ATOM 1742 N N   . PHE A 1 238  ? 166.335 157.283 201.206 1.00 7.26   ? 238  PHE A N   1 
ATOM 1743 C CA  . PHE A 1 238  ? 165.415 156.728 200.221 1.00 4.56   ? 238  PHE A CA  1 
ATOM 1744 C C   . PHE A 1 238  ? 165.240 155.228 200.421 1.00 11.05  ? 238  PHE A C   1 
ATOM 1745 O O   . PHE A 1 238  ? 164.129 154.700 200.297 1.00 10.55  ? 238  PHE A O   1 
ATOM 1746 C CB  . PHE A 1 238  ? 165.932 157.037 198.815 1.00 3.00   ? 238  PHE A CB  1 
ATOM 1747 C CG  . PHE A 1 238  ? 165.120 156.425 197.712 1.00 4.69   ? 238  PHE A CG  1 
ATOM 1748 C CD1 . PHE A 1 238  ? 163.901 156.969 197.347 1.00 9.77   ? 238  PHE A CD1 1 
ATOM 1749 C CD2 . PHE A 1 238  ? 165.586 155.319 197.024 1.00 6.64   ? 238  PHE A CD2 1 
ATOM 1750 C CE1 . PHE A 1 238  ? 163.159 156.413 196.327 1.00 7.45   ? 238  PHE A CE1 1 
ATOM 1751 C CE2 . PHE A 1 238  ? 164.847 154.759 196.003 1.00 4.79   ? 238  PHE A CE2 1 
ATOM 1752 C CZ  . PHE A 1 238  ? 163.632 155.307 195.654 1.00 5.25   ? 238  PHE A CZ  1 
ATOM 1753 N N   . ASP A 1 239  ? 166.332 154.527 200.734 1.00 8.53   ? 239  ASP A N   1 
ATOM 1754 C CA  . ASP A 1 239  ? 166.261 153.086 200.949 1.00 5.30   ? 239  ASP A CA  1 
ATOM 1755 C C   . ASP A 1 239  ? 165.546 152.745 202.251 1.00 14.03  ? 239  ASP A C   1 
ATOM 1756 O O   . ASP A 1 239  ? 164.693 151.850 202.278 1.00 15.15  ? 239  ASP A O   1 
ATOM 1757 C CB  . ASP A 1 239  ? 167.667 152.487 200.948 1.00 6.81   ? 239  ASP A CB  1 
ATOM 1758 C CG  . ASP A 1 239  ? 168.364 152.629 199.611 1.00 19.95  ? 239  ASP A CG  1 
ATOM 1759 O OD1 . ASP A 1 239  ? 167.718 153.088 198.647 1.00 23.14  ? 239  ASP A OD1 1 
ATOM 1760 O OD2 . ASP A 1 239  ? 169.561 152.283 199.526 1.00 18.71  ? 239  ASP A OD2 1 
ATOM 1761 N N   . LYS A 1 240  ? 165.878 153.442 203.342 1.00 14.81  ? 240  LYS A N   1 
ATOM 1762 C CA  . LYS A 1 240  ? 165.388 153.022 204.652 1.00 10.98  ? 240  LYS A CA  1 
ATOM 1763 C C   . LYS A 1 240  ? 163.891 153.261 204.813 1.00 13.79  ? 240  LYS A C   1 
ATOM 1764 O O   . LYS A 1 240  ? 163.219 152.493 205.510 1.00 20.72  ? 240  LYS A O   1 
ATOM 1765 C CB  . LYS A 1 240  ? 166.163 153.729 205.766 1.00 16.75  ? 240  LYS A CB  1 
ATOM 1766 C CG  . LYS A 1 240  ? 165.970 155.233 205.833 1.00 19.61  ? 240  LYS A CG  1 
ATOM 1767 C CD  . LYS A 1 240  ? 166.816 155.842 206.941 1.00 18.70  ? 240  LYS A CD  1 
ATOM 1768 C CE  . LYS A 1 240  ? 166.619 157.346 207.030 1.00 18.15  ? 240  LYS A CE  1 
ATOM 1769 N NZ  . LYS A 1 240  ? 167.449 157.951 208.107 1.00 24.01  ? 240  LYS A NZ  1 
ATOM 1770 N N   . ASN A 1 241  ? 163.353 154.307 204.195 1.00 10.70  ? 241  ASN A N   1 
ATOM 1771 C CA  . ASN A 1 241  ? 161.931 154.591 204.315 1.00 12.52  ? 241  ASN A CA  1 
ATOM 1772 C C   . ASN A 1 241  ? 161.114 153.574 203.529 1.00 14.78  ? 241  ASN A C   1 
ATOM 1773 O O   . ASN A 1 241  ? 161.533 153.087 202.477 1.00 18.65  ? 241  ASN A O   1 
ATOM 1774 C CB  . ASN A 1 241  ? 161.618 156.007 203.833 1.00 13.97  ? 241  ASN A CB  1 
ATOM 1775 C CG  . ASN A 1 241  ? 162.043 157.066 204.831 1.00 17.00  ? 241  ASN A CG  1 
ATOM 1776 O OD1 . ASN A 1 241  ? 161.358 157.317 205.821 1.00 23.63  ? 241  ASN A OD1 1 
ATOM 1777 N ND2 . ASN A 1 241  ? 163.179 157.701 204.569 1.00 15.17  ? 241  ASN A ND2 1 
ATOM 1778 N N   . LEU A 1 242  ? 159.935 153.247 204.061 1.00 17.61  ? 242  LEU A N   1 
ATOM 1779 C CA  . LEU A 1 242  ? 159.101 152.224 203.440 1.00 20.18  ? 242  LEU A CA  1 
ATOM 1780 C C   . LEU A 1 242  ? 158.502 152.699 202.123 1.00 18.36  ? 242  LEU A C   1 
ATOM 1781 O O   . LEU A 1 242  ? 158.279 151.886 201.218 1.00 24.48  ? 242  LEU A O   1 
ATOM 1782 C CB  . LEU A 1 242  ? 157.990 151.795 204.399 1.00 19.38  ? 242  LEU A CB  1 
ATOM 1783 C CG  . LEU A 1 242  ? 158.270 150.590 205.301 1.00 24.07  ? 242  LEU A CG  1 
ATOM 1784 C CD1 . LEU A 1 242  ? 159.406 150.879 206.272 1.00 22.12  ? 242  LEU A CD1 1 
ATOM 1785 C CD2 . LEU A 1 242  ? 157.011 150.183 206.049 1.00 22.22  ? 242  LEU A CD2 1 
ATOM 1786 N N   . GLN A 1 243  ? 158.231 153.994 201.995 1.00 15.34  ? 243  GLN A N   1 
ATOM 1787 C CA  . GLN A 1 243  ? 157.600 154.550 200.808 1.00 21.21  ? 243  GLN A CA  1 
ATOM 1788 C C   . GLN A 1 243  ? 158.470 155.670 200.250 1.00 20.73  ? 243  GLN A C   1 
ATOM 1789 O O   . GLN A 1 243  ? 159.537 155.986 200.784 1.00 19.77  ? 243  GLN A O   1 
ATOM 1790 C CB  . GLN A 1 243  ? 156.188 155.058 201.124 1.00 16.47  ? 243  GLN A CB  1 
ATOM 1791 C CG  . GLN A 1 243  ? 155.206 153.961 201.493 1.00 17.76  ? 243  GLN A CG  1 
ATOM 1792 C CD  . GLN A 1 243  ? 153.827 154.499 201.817 1.00 23.99  ? 243  GLN A CD  1 
ATOM 1793 O OE1 . GLN A 1 243  ? 153.609 155.710 201.832 1.00 24.32  ? 243  GLN A OE1 1 
ATOM 1794 N NE2 . GLN A 1 243  ? 152.888 153.599 202.080 1.00 23.26  ? 243  GLN A NE2 1 
ATOM 1795 N N   . VAL A 1 244  ? 158.005 156.271 199.161 1.00 19.32  ? 244  VAL A N   1 
ATOM 1796 C CA  . VAL A 1 244  ? 158.671 157.407 198.539 1.00 18.49  ? 244  VAL A CA  1 
ATOM 1797 C C   . VAL A 1 244  ? 157.885 158.654 198.916 1.00 20.41  ? 244  VAL A C   1 
ATOM 1798 O O   . VAL A 1 244  ? 156.724 158.812 198.525 1.00 21.61  ? 244  VAL A O   1 
ATOM 1799 C CB  . VAL A 1 244  ? 158.772 157.245 197.017 1.00 10.17  ? 244  VAL A CB  1 
ATOM 1800 C CG1 . VAL A 1 244  ? 159.375 158.489 196.388 1.00 10.82  ? 244  VAL A CG1 1 
ATOM 1801 C CG2 . VAL A 1 244  ? 159.595 156.019 196.671 1.00 10.04  ? 244  VAL A CG2 1 
ATOM 1802 N N   . HIS A 1 245  ? 158.513 159.541 199.680 1.00 16.16  ? 245  HIS A N   1 
ATOM 1803 C CA  . HIS A 1 245  ? 157.846 160.744 200.149 1.00 14.07  ? 245  HIS A CA  1 
ATOM 1804 C C   . HIS A 1 245  ? 157.856 161.827 199.079 1.00 18.87  ? 245  HIS A C   1 
ATOM 1805 O O   . HIS A 1 245  ? 158.703 161.843 198.182 1.00 25.35  ? 245  HIS A O   1 
ATOM 1806 C CB  . HIS A 1 245  ? 158.516 161.272 201.416 1.00 16.86  ? 245  HIS A CB  1 
ATOM 1807 C CG  . HIS A 1 245  ? 158.809 160.213 202.431 1.00 19.55  ? 245  HIS A CG  1 
ATOM 1808 N ND1 . HIS A 1 245  ? 157.828 159.412 202.975 1.00 22.54  ? 245  HIS A ND1 1 
ATOM 1809 C CD2 . HIS A 1 245  ? 159.971 159.829 203.008 1.00 19.15  ? 245  HIS A CD2 1 
ATOM 1810 C CE1 . HIS A 1 245  ? 158.375 158.577 203.840 1.00 22.15  ? 245  HIS A CE1 1 
ATOM 1811 N NE2 . HIS A 1 245  ? 159.674 158.809 203.879 1.00 20.68  ? 245  HIS A NE2 1 
ATOM 1812 N N   . ASP A 1 246  ? 156.890 162.742 199.185 1.00 17.68  ? 246  ASP A N   1 
ATOM 1813 C CA  . ASP A 1 246  ? 156.891 163.927 198.338 1.00 20.14  ? 246  ASP A CA  1 
ATOM 1814 C C   . ASP A 1 246  ? 158.098 164.813 198.605 1.00 21.08  ? 246  ASP A C   1 
ATOM 1815 O O   . ASP A 1 246  ? 158.521 165.554 197.711 1.00 19.41  ? 246  ASP A O   1 
ATOM 1816 C CB  . ASP A 1 246  ? 155.607 164.728 198.551 1.00 20.07  ? 246  ASP A CB  1 
ATOM 1817 C CG  . ASP A 1 246  ? 154.381 164.016 198.022 1.00 27.25  ? 246  ASP A CG  1 
ATOM 1818 O OD1 . ASP A 1 246  ? 154.514 163.240 197.056 1.00 21.39  ? 246  ASP A OD1 1 
ATOM 1819 O OD2 . ASP A 1 246  ? 153.281 164.231 198.574 1.00 29.52  ? 246  ASP A OD2 1 
ATOM 1820 N N   . SER A 1 247  ? 158.656 164.757 199.812 1.00 14.69  ? 247  SER A N   1 
ATOM 1821 C CA  . SER A 1 247  ? 159.796 165.580 200.179 1.00 10.17  ? 247  SER A CA  1 
ATOM 1822 C C   . SER A 1 247  ? 160.679 164.807 201.145 1.00 12.01  ? 247  SER A C   1 
ATOM 1823 O O   . SER A 1 247  ? 160.180 164.118 202.038 1.00 23.14  ? 247  SER A O   1 
ATOM 1824 C CB  . SER A 1 247  ? 159.348 166.902 200.811 1.00 19.55  ? 247  SER A CB  1 
ATOM 1825 O OG  . SER A 1 247  ? 158.703 166.678 202.052 1.00 24.65  ? 247  SER A OG  1 
ATOM 1826 N N   . TYR A 1 248  ? 161.989 164.929 200.958 1.00 12.80  ? 248  TYR A N   1 
ATOM 1827 C CA  . TYR A 1 248  ? 162.979 164.285 201.808 1.00 3.19   ? 248  TYR A CA  1 
ATOM 1828 C C   . TYR A 1 248  ? 163.785 165.349 202.538 1.00 9.13   ? 248  TYR A C   1 
ATOM 1829 O O   . TYR A 1 248  ? 164.074 166.412 201.980 1.00 20.60  ? 248  TYR A O   1 
ATOM 1830 C CB  . TYR A 1 248  ? 163.915 163.391 200.990 1.00 12.76  ? 248  TYR A CB  1 
ATOM 1831 C CG  . TYR A 1 248  ? 163.302 162.092 200.529 1.00 15.95  ? 248  TYR A CG  1 
ATOM 1832 C CD1 . TYR A 1 248  ? 162.412 162.059 199.463 1.00 14.16  ? 248  TYR A CD1 1 
ATOM 1833 C CD2 . TYR A 1 248  ? 163.617 160.895 201.156 1.00 9.96   ? 248  TYR A CD2 1 
ATOM 1834 C CE1 . TYR A 1 248  ? 161.852 160.869 199.039 1.00 14.82  ? 248  TYR A CE1 1 
ATOM 1835 C CE2 . TYR A 1 248  ? 163.063 159.704 200.740 1.00 11.33  ? 248  TYR A CE2 1 
ATOM 1836 C CZ  . TYR A 1 248  ? 162.182 159.696 199.682 1.00 14.40  ? 248  TYR A CZ  1 
ATOM 1837 O OH  . TYR A 1 248  ? 161.630 158.508 199.268 1.00 12.93  ? 248  TYR A OH  1 
ATOM 1838 N N   . ARG A 1 249  ? 164.145 165.063 203.785 1.00 17.71  ? 249  ARG A N   1 
ATOM 1839 C CA  . ARG A 1 249  ? 164.893 165.988 204.635 1.00 10.69  ? 249  ARG A CA  1 
ATOM 1840 C C   . ARG A 1 249  ? 166.162 165.280 205.106 1.00 15.07  ? 249  ARG A C   1 
ATOM 1841 O O   . ARG A 1 249  ? 166.146 164.545 206.095 1.00 25.40  ? 249  ARG A O   1 
ATOM 1842 C CB  . ARG A 1 249  ? 164.036 166.456 205.807 1.00 12.83  ? 249  ARG A CB  1 
ATOM 1843 C CG  . ARG A 1 249  ? 164.710 167.479 206.695 1.00 22.91  ? 249  ARG A CG  1 
ATOM 1844 C CD  . ARG A 1 249  ? 163.790 167.944 207.810 1.00 22.09  ? 249  ARG A CD  1 
ATOM 1845 N NE  . ARG A 1 249  ? 164.422 168.960 208.644 1.00 19.84  ? 249  ARG A NE  1 
ATOM 1846 C CZ  . ARG A 1 249  ? 165.149 168.698 209.721 1.00 23.10  ? 249  ARG A CZ  1 
ATOM 1847 N NH1 . ARG A 1 249  ? 165.358 167.458 210.131 1.00 24.38  ? 249  ARG A NH1 1 
ATOM 1848 N NH2 . ARG A 1 249  ? 165.682 169.707 210.405 1.00 19.37  ? 249  ARG A NH2 1 
ATOM 1849 N N   . ILE A 1 250  ? 167.262 165.509 204.399 1.00 13.98  ? 250  ILE A N   1 
ATOM 1850 C CA  . ILE A 1 250  ? 168.532 164.837 204.661 1.00 21.46  ? 250  ILE A CA  1 
ATOM 1851 C C   . ILE A 1 250  ? 169.461 165.819 205.368 1.00 23.59  ? 250  ILE A C   1 
ATOM 1852 O O   . ILE A 1 250  ? 169.768 166.877 204.802 1.00 28.55  ? 250  ILE A O   1 
ATOM 1853 C CB  . ILE A 1 250  ? 169.182 164.315 203.371 1.00 17.34  ? 250  ILE A CB  1 
ATOM 1854 C CG1 . ILE A 1 250  ? 168.307 163.255 202.696 1.00 19.11  ? 250  ILE A CG1 1 
ATOM 1855 C CG2 . ILE A 1 250  ? 170.564 163.769 203.664 1.00 12.75  ? 250  ILE A CG2 1 
ATOM 1856 C CD1 . ILE A 1 250  ? 167.305 163.817 201.726 1.00 20.61  ? 250  ILE A CD1 1 
ATOM 1857 N N   . PRO A 1 251  ? 169.918 165.521 206.585 1.00 29.48  ? 251  PRO A N   1 
ATOM 1858 C CA  . PRO A 1 251  ? 170.938 166.361 207.223 1.00 31.24  ? 251  PRO A CA  1 
ATOM 1859 C C   . PRO A 1 251  ? 172.337 166.043 206.719 1.00 31.49  ? 251  PRO A C   1 
ATOM 1860 O O   . PRO A 1 251  ? 172.707 164.887 206.506 1.00 34.09  ? 251  PRO A O   1 
ATOM 1861 C CB  . PRO A 1 251  ? 170.799 166.000 208.709 1.00 34.56  ? 251  PRO A CB  1 
ATOM 1862 C CG  . PRO A 1 251  ? 170.265 164.612 208.701 1.00 35.84  ? 251  PRO A CG  1 
ATOM 1863 C CD  . PRO A 1 251  ? 169.357 164.524 207.511 1.00 33.57  ? 251  PRO A CD  1 
ATOM 1864 N N   . GLY A 1 252  ? 173.129 167.100 206.527 1.00 50.70  ? 252  GLY A N   1 
ATOM 1865 C CA  . GLY A 1 252  ? 174.497 166.957 206.079 1.00 54.68  ? 252  GLY A CA  1 
ATOM 1866 C C   . GLY A 1 252  ? 175.470 166.755 207.228 1.00 59.13  ? 252  GLY A C   1 
ATOM 1867 O O   . GLY A 1 252  ? 175.107 166.739 208.403 1.00 57.31  ? 252  GLY A O   1 
ATOM 1868 N N   . GLU A 1 253  ? 176.745 166.599 206.863 1.00 73.95  ? 253  GLU A N   1 
ATOM 1869 C CA  . GLU A 1 253  ? 177.784 166.371 207.862 1.00 73.57  ? 253  GLU A CA  1 
ATOM 1870 C C   . GLU A 1 253  ? 178.236 167.661 208.534 1.00 74.65  ? 253  GLU A C   1 
ATOM 1871 O O   . GLU A 1 253  ? 178.691 167.628 209.683 1.00 75.10  ? 253  GLU A O   1 
ATOM 1872 C CB  . GLU A 1 253  ? 178.981 165.662 207.224 1.00 73.41  ? 253  GLU A CB  1 
ATOM 1873 C CG  . GLU A 1 253  ? 179.770 166.511 206.237 1.00 74.54  ? 253  GLU A CG  1 
ATOM 1874 C CD  . GLU A 1 253  ? 179.181 166.494 204.838 1.00 75.21  ? 253  GLU A CD  1 
ATOM 1875 O OE1 . GLU A 1 253  ? 178.013 166.079 204.683 1.00 74.78  ? 253  GLU A OE1 1 
ATOM 1876 O OE2 . GLU A 1 253  ? 179.889 166.896 203.891 1.00 73.43  ? 253  GLU A OE2 1 
ATOM 1877 N N   . ASN A 1 254  ? 178.120 168.798 207.848 1.00 71.86  ? 254  ASN A N   1 
ATOM 1878 C CA  . ASN A 1 254  ? 178.527 170.087 208.388 1.00 72.95  ? 254  ASN A CA  1 
ATOM 1879 C C   . ASN A 1 254  ? 177.383 170.820 209.075 1.00 71.83  ? 254  ASN A C   1 
ATOM 1880 O O   . ASN A 1 254  ? 177.460 172.040 209.257 1.00 72.32  ? 254  ASN A O   1 
ATOM 1881 C CB  . ASN A 1 254  ? 179.109 170.965 207.277 1.00 72.60  ? 254  ASN A CB  1 
ATOM 1882 C CG  . ASN A 1 254  ? 180.449 170.465 206.780 1.00 73.72  ? 254  ASN A CG  1 
ATOM 1883 O OD1 . ASN A 1 254  ? 181.301 170.053 207.566 1.00 73.40  ? 254  ASN A OD1 1 
ATOM 1884 N ND2 . ASN A 1 254  ? 180.643 170.501 205.466 1.00 73.32  ? 254  ASN A ND2 1 
ATOM 1885 N N   . GLY A 1 255  ? 176.328 170.107 209.458 1.00 61.55  ? 255  GLY A N   1 
ATOM 1886 C CA  . GLY A 1 255  ? 175.122 170.754 209.923 1.00 61.57  ? 255  GLY A CA  1 
ATOM 1887 C C   . GLY A 1 255  ? 174.258 171.310 208.818 1.00 60.75  ? 255  GLY A C   1 
ATOM 1888 O O   . GLY A 1 255  ? 173.243 171.953 209.108 1.00 59.14  ? 255  GLY A O   1 
ATOM 1889 N N   . GLU A 1 256  ? 174.632 171.085 207.561 1.00 45.53  ? 256  GLU A N   1 
ATOM 1890 C CA  . GLU A 1 256  ? 173.848 171.559 206.433 1.00 43.51  ? 256  GLU A CA  1 
ATOM 1891 C C   . GLU A 1 256  ? 172.579 170.732 206.290 1.00 41.57  ? 256  GLU A C   1 
ATOM 1892 O O   . GLU A 1 256  ? 172.605 169.503 206.388 1.00 42.14  ? 256  GLU A O   1 
ATOM 1893 C CB  . GLU A 1 256  ? 174.671 171.490 205.147 1.00 43.65  ? 256  GLU A CB  1 
ATOM 1894 C CG  . GLU A 1 256  ? 176.047 172.122 205.267 1.00 45.70  ? 256  GLU A CG  1 
ATOM 1895 C CD  . GLU A 1 256  ? 176.586 172.603 203.936 1.00 44.02  ? 256  GLU A CD  1 
ATOM 1896 O OE1 . GLU A 1 256  ? 176.400 171.892 202.926 1.00 41.27  ? 256  GLU A OE1 1 
ATOM 1897 O OE2 . GLU A 1 256  ? 177.195 173.693 203.898 1.00 43.57  ? 256  GLU A OE2 1 
ATOM 1898 N N   . LEU A 1 257  ? 171.467 171.417 206.059 1.00 32.66  ? 257  LEU A N   1 
ATOM 1899 C CA  . LEU A 1 257  ? 170.162 170.781 205.950 1.00 29.66  ? 257  LEU A CA  1 
ATOM 1900 C C   . LEU A 1 257  ? 169.721 170.815 204.492 1.00 31.08  ? 257  LEU A C   1 
ATOM 1901 O O   . LEU A 1 257  ? 169.576 171.894 203.909 1.00 29.18  ? 257  LEU A O   1 
ATOM 1902 C CB  . LEU A 1 257  ? 169.152 171.487 206.853 1.00 29.75  ? 257  LEU A CB  1 
ATOM 1903 C CG  . LEU A 1 257  ? 167.668 171.193 206.664 1.00 28.09  ? 257  LEU A CG  1 
ATOM 1904 C CD1 . LEU A 1 257  ? 167.353 169.801 207.165 1.00 26.74  ? 257  LEU A CD1 1 
ATOM 1905 C CD2 . LEU A 1 257  ? 166.852 172.228 207.417 1.00 27.88  ? 257  LEU A CD2 1 
ATOM 1906 N N   . SER A 1 258  ? 169.512 169.638 203.910 1.00 20.11  ? 258  SER A N   1 
ATOM 1907 C CA  . SER A 1 258  ? 169.192 169.502 202.495 1.00 15.11  ? 258  SER A CA  1 
ATOM 1908 C C   . SER A 1 258  ? 167.767 168.986 202.347 1.00 15.01  ? 258  SER A C   1 
ATOM 1909 O O   . SER A 1 258  ? 167.422 167.939 202.904 1.00 24.04  ? 258  SER A O   1 
ATOM 1910 C CB  . SER A 1 258  ? 170.178 168.564 201.800 1.00 15.83  ? 258  SER A CB  1 
ATOM 1911 O OG  . SER A 1 258  ? 169.850 168.407 200.432 1.00 25.92  ? 258  SER A OG  1 
ATOM 1912 N N   . HIS A 1 259  ? 166.950 169.719 201.598 1.00 9.38   ? 259  HIS A N   1 
ATOM 1913 C CA  . HIS A 1 259  ? 165.581 169.325 201.299 1.00 4.51   ? 259  HIS A CA  1 
ATOM 1914 C C   . HIS A 1 259  ? 165.503 168.865 199.853 1.00 8.89   ? 259  HIS A C   1 
ATOM 1915 O O   . HIS A 1 259  ? 165.975 169.561 198.949 1.00 13.57  ? 259  HIS A O   1 
ATOM 1916 C CB  . HIS A 1 259  ? 164.602 170.478 201.528 1.00 5.04   ? 259  HIS A CB  1 
ATOM 1917 C CG  . HIS A 1 259  ? 164.678 171.076 202.896 1.00 13.07  ? 259  HIS A CG  1 
ATOM 1918 N ND1 . HIS A 1 259  ? 163.841 170.694 203.922 1.00 18.40  ? 259  HIS A ND1 1 
ATOM 1919 C CD2 . HIS A 1 259  ? 165.484 172.037 203.405 1.00 16.48  ? 259  HIS A CD2 1 
ATOM 1920 C CE1 . HIS A 1 259  ? 164.132 171.390 205.006 1.00 17.08  ? 259  HIS A CE1 1 
ATOM 1921 N NE2 . HIS A 1 259  ? 165.124 172.213 204.718 1.00 20.69  ? 259  HIS A NE2 1 
ATOM 1922 N N   . VAL A 1 260  ? 164.909 167.697 199.637 1.00 11.42  ? 260  VAL A N   1 
ATOM 1923 C CA  . VAL A 1 260  ? 164.723 167.142 198.304 1.00 3.70   ? 260  VAL A CA  1 
ATOM 1924 C C   . VAL A 1 260  ? 163.229 167.072 198.036 1.00 3.23   ? 260  VAL A C   1 
ATOM 1925 O O   . VAL A 1 260  ? 162.508 166.318 198.699 1.00 15.71  ? 260  VAL A O   1 
ATOM 1926 C CB  . VAL A 1 260  ? 165.378 165.761 198.170 1.00 4.61   ? 260  VAL A CB  1 
ATOM 1927 C CG1 . VAL A 1 260  ? 165.078 165.172 196.814 1.00 6.84   ? 260  VAL A CG1 1 
ATOM 1928 C CG2 . VAL A 1 260  ? 166.873 165.864 198.386 1.00 6.48   ? 260  VAL A CG2 1 
ATOM 1929 N N   . ILE A 1 261  ? 162.763 167.853 197.067 1.00 5.50   ? 261  ILE A N   1 
ATOM 1930 C CA  . ILE A 1 261  ? 161.360 167.870 196.672 1.00 9.64   ? 261  ILE A CA  1 
ATOM 1931 C C   . ILE A 1 261  ? 161.213 166.984 195.445 1.00 7.10   ? 261  ILE A C   1 
ATOM 1932 O O   . ILE A 1 261  ? 161.953 167.136 194.467 1.00 7.17   ? 261  ILE A O   1 
ATOM 1933 C CB  . ILE A 1 261  ? 160.869 169.297 196.388 1.00 13.68  ? 261  ILE A CB  1 
ATOM 1934 C CG1 . ILE A 1 261  ? 160.946 170.150 197.654 1.00 12.47  ? 261  ILE A CG1 1 
ATOM 1935 C CG2 . ILE A 1 261  ? 159.446 169.272 195.853 1.00 13.40  ? 261  ILE A CG2 1 
ATOM 1936 C CD1 . ILE A 1 261  ? 160.727 171.621 197.402 1.00 17.11  ? 261  ILE A CD1 1 
ATOM 1937 N N   . ILE A 1 262  ? 160.263 166.058 195.494 1.00 8.82   ? 262  ILE A N   1 
ATOM 1938 C CA  . ILE A 1 262  ? 160.105 165.037 194.467 1.00 11.37  ? 262  ILE A CA  1 
ATOM 1939 C C   . ILE A 1 262  ? 158.836 165.353 193.676 1.00 14.38  ? 262  ILE A C   1 
ATOM 1940 O O   . ILE A 1 262  ? 157.725 165.222 194.211 1.00 15.84  ? 262  ILE A O   1 
ATOM 1941 C CB  . ILE A 1 262  ? 160.049 163.632 195.078 1.00 10.97  ? 262  ILE A CB  1 
ATOM 1942 C CG1 . ILE A 1 262  ? 161.324 163.344 195.869 1.00 10.10  ? 262  ILE A CG1 1 
ATOM 1943 C CG2 . ILE A 1 262  ? 159.926 162.612 193.993 1.00 13.13  ? 262  ILE A CG2 1 
ATOM 1944 C CD1 . ILE A 1 262  ? 162.574 163.379 195.028 1.00 9.99   ? 262  ILE A CD1 1 
ATOM 1945 N N   . PRO A 1 263  ? 158.946 165.780 192.421 1.00 13.76  ? 263  PRO A N   1 
ATOM 1946 C CA  . PRO A 1 263  ? 157.752 166.018 191.597 1.00 11.44  ? 263  PRO A CA  1 
ATOM 1947 C C   . PRO A 1 263  ? 156.982 164.732 191.355 1.00 15.46  ? 263  PRO A C   1 
ATOM 1948 O O   . PRO A 1 263  ? 157.541 163.633 191.478 1.00 19.34  ? 263  PRO A O   1 
ATOM 1949 C CB  . PRO A 1 263  ? 158.326 166.573 190.286 1.00 7.90   ? 263  PRO A CB  1 
ATOM 1950 C CG  . PRO A 1 263  ? 159.662 167.104 190.630 1.00 8.62   ? 263  PRO A CG  1 
ATOM 1951 C CD  . PRO A 1 263  ? 160.156 166.401 191.858 1.00 6.45   ? 263  PRO A CD  1 
ATOM 1952 N N   . PRO A 1 264  ? 155.690 164.834 191.025 1.00 18.43  ? 264  PRO A N   1 
ATOM 1953 C CA  . PRO A 1 264  ? 154.877 163.619 190.837 1.00 13.70  ? 264  PRO A CA  1 
ATOM 1954 C C   . PRO A 1 264  ? 155.445 162.616 189.846 1.00 16.51  ? 264  PRO A C   1 
ATOM 1955 O O   . PRO A 1 264  ? 155.343 161.408 190.088 1.00 21.24  ? 264  PRO A O   1 
ATOM 1956 C CB  . PRO A 1 264  ? 153.532 164.184 190.348 1.00 15.00  ? 264  PRO A CB  1 
ATOM 1957 C CG  . PRO A 1 264  ? 153.615 165.704 190.541 1.00 18.17  ? 264  PRO A CG  1 
ATOM 1958 C CD  . PRO A 1 264  ? 154.832 165.979 191.358 1.00 19.15  ? 264  PRO A CD  1 
ATOM 1959 N N   . GLU A 1 265  ? 156.027 163.066 188.733 1.00 15.69  ? 265  GLU A N   1 
ATOM 1960 C CA  . GLU A 1 265  ? 156.575 162.126 187.756 1.00 15.70  ? 265  GLU A CA  1 
ATOM 1961 C C   . GLU A 1 265  ? 157.850 161.471 188.275 1.00 14.02  ? 265  GLU A C   1 
ATOM 1962 O O   . GLU A 1 265  ? 158.031 160.248 188.159 1.00 20.27  ? 265  GLU A O   1 
ATOM 1963 C CB  . GLU A 1 265  ? 156.825 162.849 186.432 1.00 13.84  ? 265  GLU A CB  1 
ATOM 1964 C CG  . GLU A 1 265  ? 157.952 163.868 186.479 1.00 16.83  ? 265  GLU A CG  1 
ATOM 1965 C CD  . GLU A 1 265  ? 157.530 165.215 186.982 1.00 26.62  ? 265  GLU A CD  1 
ATOM 1966 O OE1 . GLU A 1 265  ? 156.440 165.306 187.579 1.00 24.49  ? 265  GLU A OE1 1 
ATOM 1967 O OE2 . GLU A 1 265  ? 158.286 166.190 186.788 1.00 30.54  ? 265  GLU A OE2 1 
ATOM 1968 N N   . VAL A 1 266  ? 158.745 162.272 188.852 1.00 7.68   ? 266  VAL A N   1 
ATOM 1969 C CA  . VAL A 1 266  ? 159.932 161.724 189.490 1.00 9.91   ? 266  VAL A CA  1 
ATOM 1970 C C   . VAL A 1 266  ? 159.522 160.807 190.630 1.00 12.96  ? 266  VAL A C   1 
ATOM 1971 O O   . VAL A 1 266  ? 160.142 159.764 190.861 1.00 17.07  ? 266  VAL A O   1 
ATOM 1972 C CB  . VAL A 1 266  ? 160.854 162.862 189.967 1.00 9.14   ? 266  VAL A CB  1 
ATOM 1973 C CG1 . VAL A 1 266  ? 162.148 162.303 190.526 1.00 8.53   ? 266  VAL A CG1 1 
ATOM 1974 C CG2 . VAL A 1 266  ? 161.138 163.825 188.826 1.00 7.72   ? 266  VAL A CG2 1 
ATOM 1975 N N   . LYS A 1 267  ? 158.453 161.171 191.345 1.00 11.94  ? 267  LYS A N   1 
ATOM 1976 C CA  . LYS A 1 267  ? 157.934 160.304 192.397 1.00 6.62   ? 267  LYS A CA  1 
ATOM 1977 C C   . LYS A 1 267  ? 157.442 158.981 191.837 1.00 9.95   ? 267  LYS A C   1 
ATOM 1978 O O   . LYS A 1 267  ? 157.622 157.937 192.463 1.00 17.60  ? 267  LYS A O   1 
ATOM 1979 C CB  . LYS A 1 267  ? 156.806 160.996 193.159 1.00 12.75  ? 267  LYS A CB  1 
ATOM 1980 C CG  . LYS A 1 267  ? 156.300 160.179 194.334 1.00 14.41  ? 267  LYS A CG  1 
ATOM 1981 C CD  . LYS A 1 267  ? 155.241 160.915 195.120 1.00 14.10  ? 267  LYS A CD  1 
ATOM 1982 C CE  . LYS A 1 267  ? 154.749 160.074 196.285 1.00 21.15  ? 267  LYS A CE  1 
ATOM 1983 N NZ  . LYS A 1 267  ? 153.702 160.778 197.075 1.00 24.56  ? 267  LYS A NZ  1 
ATOM 1984 N N   . GLU A 1 268  ? 156.797 159.003 190.672 1.00 8.68   ? 268  GLU A N   1 
ATOM 1985 C CA  . GLU A 1 268  ? 156.292 157.766 190.087 1.00 10.05  ? 268  GLU A CA  1 
ATOM 1986 C C   . GLU A 1 268  ? 157.441 156.845 189.692 1.00 8.61   ? 268  GLU A C   1 
ATOM 1987 O O   . GLU A 1 268  ? 157.408 155.633 189.962 1.00 10.25  ? 268  GLU A O   1 
ATOM 1988 C CB  . GLU A 1 268  ? 155.419 158.096 188.877 1.00 10.35  ? 268  GLU A CB  1 
ATOM 1989 C CG  . GLU A 1 268  ? 154.776 156.903 188.191 1.00 16.53  ? 268  GLU A CG  1 
ATOM 1990 C CD  . GLU A 1 268  ? 153.773 156.207 189.082 1.00 26.57  ? 268  GLU A CD  1 
ATOM 1991 O OE1 . GLU A 1 268  ? 153.215 156.852 189.982 1.00 25.35  ? 268  GLU A OE1 1 
ATOM 1992 O OE2 . GLU A 1 268  ? 153.507 155.046 188.871 1.00 27.58  ? 268  GLU A OE2 1 
ATOM 1993 N N   . VAL A 1 269  ? 158.474 157.415 189.071 1.00 7.77   ? 269  VAL A N   1 
ATOM 1994 C CA  . VAL A 1 269  ? 159.640 156.618 188.698 1.00 6.78   ? 269  VAL A CA  1 
ATOM 1995 C C   . VAL A 1 269  ? 160.340 156.069 189.938 1.00 9.92   ? 269  VAL A C   1 
ATOM 1996 O O   . VAL A 1 269  ? 160.766 154.907 189.964 1.00 17.74  ? 269  VAL A O   1 
ATOM 1997 C CB  . VAL A 1 269  ? 160.600 157.438 187.821 1.00 6.57   ? 269  VAL A CB  1 
ATOM 1998 C CG1 . VAL A 1 269  ? 161.696 156.544 187.298 1.00 3.94   ? 269  VAL A CG1 1 
ATOM 1999 C CG2 . VAL A 1 269  ? 159.846 158.080 186.671 1.00 7.83   ? 269  VAL A CG2 1 
ATOM 2000 N N   . LEU A 1 270  ? 160.480 156.892 190.982 1.00 8.11   ? 270  LEU A N   1 
ATOM 2001 C CA  . LEU A 1 270  ? 161.113 156.412 192.206 1.00 1.00   ? 270  LEU A CA  1 
ATOM 2002 C C   . LEU A 1 270  ? 160.235 155.412 192.944 1.00 2.84   ? 270  LEU A C   1 
ATOM 2003 O O   . LEU A 1 270  ? 160.748 154.594 193.709 1.00 11.24  ? 270  LEU A O   1 
ATOM 2004 C CB  . LEU A 1 270  ? 161.464 157.579 193.127 1.00 9.64   ? 270  LEU A CB  1 
ATOM 2005 C CG  . LEU A 1 270  ? 162.523 158.571 192.647 1.00 3.29   ? 270  LEU A CG  1 
ATOM 2006 C CD1 . LEU A 1 270  ? 162.263 159.938 193.246 1.00 7.79   ? 270  LEU A CD1 1 
ATOM 2007 C CD2 . LEU A 1 270  ? 163.919 158.087 192.995 1.00 6.75   ? 270  LEU A CD2 1 
ATOM 2008 N N   . ASN A 1 271  ? 158.917 155.471 192.750 1.00 7.41   ? 271  ASN A N   1 
ATOM 2009 C CA  . ASN A 1 271  ? 158.039 154.437 193.283 1.00 7.57   ? 271  ASN A CA  1 
ATOM 2010 C C   . ASN A 1 271  ? 158.300 153.106 192.601 1.00 10.57  ? 271  ASN A C   1 
ATOM 2011 O O   . ASN A 1 271  ? 158.379 152.065 193.263 1.00 12.84  ? 271  ASN A O   1 
ATOM 2012 C CB  . ASN A 1 271  ? 156.576 154.841 193.103 1.00 5.45   ? 271  ASN A CB  1 
ATOM 2013 C CG  . ASN A 1 271  ? 156.047 155.656 194.261 1.00 13.54  ? 271  ASN A CG  1 
ATOM 2014 O OD1 . ASN A 1 271  ? 156.568 155.586 195.372 1.00 21.73  ? 271  ASN A OD1 1 
ATOM 2015 N ND2 . ASN A 1 271  ? 154.999 156.430 194.009 1.00 12.20  ? 271  ASN A ND2 1 
ATOM 2016 N N   . SER A 1 272  ? 158.429 153.121 191.274 1.00 11.46  ? 272  SER A N   1 
ATOM 2017 C CA  . SER A 1 272  ? 158.727 151.883 190.561 1.00 9.57   ? 272  SER A CA  1 
ATOM 2018 C C   . SER A 1 272  ? 160.105 151.345 190.927 1.00 3.27   ? 272  SER A C   1 
ATOM 2019 O O   . SER A 1 272  ? 160.294 150.129 191.041 1.00 8.80   ? 272  SER A O   1 
ATOM 2020 C CB  . SER A 1 272  ? 158.607 152.099 189.057 1.00 6.60   ? 272  SER A CB  1 
ATOM 2021 O OG  . SER A 1 272  ? 157.269 152.416 188.724 1.00 15.80  ? 272  SER A OG  1 
ATOM 2022 N N   . ILE A 1 273  ? 161.084 152.233 191.108 1.00 3.96   ? 273  ILE A N   1 
ATOM 2023 C CA  . ILE A 1 273  ? 162.416 151.791 191.514 1.00 7.63   ? 273  ILE A CA  1 
ATOM 2024 C C   . ILE A 1 273  ? 162.390 151.244 192.938 1.00 7.81   ? 273  ILE A C   1 
ATOM 2025 O O   . ILE A 1 273  ? 163.024 150.227 193.242 1.00 10.81  ? 273  ILE A O   1 
ATOM 2026 C CB  . ILE A 1 273  ? 163.424 152.945 191.371 1.00 10.10  ? 273  ILE A CB  1 
ATOM 2027 C CG1 . ILE A 1 273  ? 163.900 153.060 189.929 1.00 6.70   ? 273  ILE A CG1 1 
ATOM 2028 C CG2 . ILE A 1 273  ? 164.620 152.740 192.283 1.00 4.91   ? 273  ILE A CG2 1 
ATOM 2029 C CD1 . ILE A 1 273  ? 164.738 154.275 189.693 1.00 7.20   ? 273  ILE A CD1 1 
ATOM 2030 N N   . HIS A 1 274  ? 161.651 151.908 193.828 1.00 10.17  ? 274  HIS A N   1 
ATOM 2031 C CA  . HIS A 1 274  ? 161.619 151.534 195.236 1.00 5.61   ? 274  HIS A CA  1 
ATOM 2032 C C   . HIS A 1 274  ? 160.872 150.227 195.458 1.00 13.37  ? 274  HIS A C   1 
ATOM 2033 O O   . HIS A 1 274  ? 161.149 149.515 196.430 1.00 16.62  ? 274  HIS A O   1 
ATOM 2034 C CB  . HIS A 1 274  ? 160.976 152.660 196.045 1.00 6.25   ? 274  HIS A CB  1 
ATOM 2035 C CG  . HIS A 1 274  ? 161.384 152.685 197.483 1.00 9.88   ? 274  HIS A CG  1 
ATOM 2036 N ND1 . HIS A 1 274  ? 160.557 152.253 198.496 1.00 11.61  ? 274  HIS A ND1 1 
ATOM 2037 C CD2 . HIS A 1 274  ? 162.528 153.094 198.079 1.00 13.31  ? 274  HIS A CD2 1 
ATOM 2038 C CE1 . HIS A 1 274  ? 161.176 152.391 199.654 1.00 11.22  ? 274  HIS A CE1 1 
ATOM 2039 N NE2 . HIS A 1 274  ? 162.373 152.901 199.429 1.00 12.15  ? 274  HIS A NE2 1 
ATOM 2040 N N   . SER A 1 275  ? 159.922 149.900 194.580 1.00 14.21  ? 275  SER A N   1 
ATOM 2041 C CA  . SER A 1 275  ? 159.192 148.645 194.701 1.00 6.90   ? 275  SER A CA  1 
ATOM 2042 C C   . SER A 1 275  ? 160.083 147.433 194.470 1.00 5.97   ? 275  SER A C   1 
ATOM 2043 O O   . SER A 1 275  ? 159.736 146.333 194.912 1.00 11.26  ? 275  SER A O   1 
ATOM 2044 C CB  . SER A 1 275  ? 158.020 148.626 193.720 1.00 9.98   ? 275  SER A CB  1 
ATOM 2045 O OG  . SER A 1 275  ? 158.417 148.101 192.465 1.00 13.14  ? 275  SER A OG  1 
ATOM 2046 N N   . ILE A 1 276  ? 161.213 147.607 193.794 1.00 4.68   ? 276  ILE A N   1 
ATOM 2047 C CA  . ILE A 1 276  ? 162.171 146.527 193.582 1.00 9.41   ? 276  ILE A CA  1 
ATOM 2048 C C   . ILE A 1 276  ? 162.880 146.253 194.904 1.00 15.58  ? 276  ILE A C   1 
ATOM 2049 O O   . ILE A 1 276  ? 163.506 147.162 195.470 1.00 18.91  ? 276  ILE A O   1 
ATOM 2050 C CB  . ILE A 1 276  ? 163.166 146.878 192.466 1.00 7.39   ? 276  ILE A CB  1 
ATOM 2051 C CG1 . ILE A 1 276  ? 162.415 147.262 191.190 1.00 6.33   ? 276  ILE A CG1 1 
ATOM 2052 C CG2 . ILE A 1 276  ? 164.101 145.715 192.198 1.00 9.29   ? 276  ILE A CG2 1 
ATOM 2053 C CD1 . ILE A 1 276  ? 163.229 148.099 190.230 1.00 9.04   ? 276  ILE A CD1 1 
ATOM 2054 N N   . PRO A 1 277  ? 162.813 145.028 195.428 1.00 16.00  ? 277  PRO A N   1 
ATOM 2055 C CA  . PRO A 1 277  ? 163.354 144.754 196.771 1.00 12.40  ? 277  PRO A CA  1 
ATOM 2056 C C   . PRO A 1 277  ? 164.872 144.854 196.782 1.00 14.89  ? 277  PRO A C   1 
ATOM 2057 O O   . PRO A 1 277  ? 165.562 144.119 196.073 1.00 17.22  ? 277  PRO A O   1 
ATOM 2058 C CB  . PRO A 1 277  ? 162.880 143.326 197.074 1.00 13.37  ? 277  PRO A CB  1 
ATOM 2059 C CG  . PRO A 1 277  ? 162.230 142.810 195.851 1.00 19.07  ? 277  PRO A CG  1 
ATOM 2060 C CD  . PRO A 1 277  ? 162.185 143.857 194.797 1.00 16.66  ? 277  PRO A CD  1 
ATOM 2061 N N   . GLY A 1 278  ? 165.389 145.771 197.597 1.00 17.75  ? 278  GLY A N   1 
ATOM 2062 C CA  . GLY A 1 278  ? 166.820 145.968 197.697 1.00 14.90  ? 278  GLY A CA  1 
ATOM 2063 C C   . GLY A 1 278  ? 167.445 146.665 196.515 1.00 13.59  ? 278  GLY A C   1 
ATOM 2064 O O   . GLY A 1 278  ? 168.675 146.739 196.440 1.00 18.04  ? 278  GLY A O   1 
ATOM 2065 N N   . ARG A 1 279  ? 166.631 147.186 195.596 1.00 14.93  ? 279  ARG A N   1 
ATOM 2066 C CA  . ARG A 1 279  ? 167.108 147.771 194.343 1.00 12.83  ? 279  ARG A CA  1 
ATOM 2067 C C   . ARG A 1 279  ? 168.003 146.790 193.592 1.00 20.71  ? 279  ARG A C   1 
ATOM 2068 O O   . ARG A 1 279  ? 168.988 147.169 192.954 1.00 23.57  ? 279  ARG A O   1 
ATOM 2069 C CB  . ARG A 1 279  ? 167.824 149.100 194.588 1.00 8.64   ? 279  ARG A CB  1 
ATOM 2070 C CG  . ARG A 1 279  ? 166.879 150.285 194.708 1.00 16.13  ? 279  ARG A CG  1 
ATOM 2071 C CD  . ARG A 1 279  ? 167.620 151.610 194.829 1.00 15.18  ? 279  ARG A CD  1 
ATOM 2072 N NE  . ARG A 1 279  ? 168.619 151.607 195.891 1.00 15.69  ? 279  ARG A NE  1 
ATOM 2073 C CZ  . ARG A 1 279  ? 169.921 151.449 195.696 1.00 20.52  ? 279  ARG A CZ  1 
ATOM 2074 N NH1 . ARG A 1 279  ? 170.422 151.277 194.484 1.00 15.49  ? 279  ARG A NH1 1 
ATOM 2075 N NH2 . ARG A 1 279  ? 170.740 151.462 196.743 1.00 19.52  ? 279  ARG A NH2 1 
ATOM 2076 N N   . ARG A 1 280  ? 167.653 145.509 193.673 1.00 20.13  ? 280  ARG A N   1 
ATOM 2077 C CA  . ARG A 1 280  ? 168.353 144.441 192.973 1.00 14.37  ? 280  ARG A CA  1 
ATOM 2078 C C   . ARG A 1 280  ? 167.413 143.860 191.929 1.00 20.15  ? 280  ARG A C   1 
ATOM 2079 O O   . ARG A 1 280  ? 166.328 143.375 192.266 1.00 25.12  ? 280  ARG A O   1 
ATOM 2080 C CB  . ARG A 1 280  ? 168.819 143.359 193.946 1.00 17.18  ? 280  ARG A CB  1 
ATOM 2081 C CG  . ARG A 1 280  ? 169.904 143.813 194.907 1.00 21.60  ? 280  ARG A CG  1 
ATOM 2082 C CD  . ARG A 1 280  ? 170.315 142.690 195.844 1.00 22.06  ? 280  ARG A CD  1 
ATOM 2083 N NE  . ARG A 1 280  ? 171.341 143.113 196.788 1.00 27.76  ? 280  ARG A NE  1 
ATOM 2084 C CZ  . ARG A 1 280  ? 171.836 142.346 197.750 1.00 32.79  ? 280  ARG A CZ  1 
ATOM 2085 N NH1 . ARG A 1 280  ? 171.418 141.104 197.927 1.00 32.15  ? 280  ARG A NH1 1 
ATOM 2086 N NH2 . ARG A 1 280  ? 172.774 142.838 198.554 1.00 28.49  ? 280  ARG A NH2 1 
ATOM 2087 N N   . VAL A 1 281  ? 167.832 143.903 190.667 1.00 21.77  ? 281  VAL A N   1 
ATOM 2088 C CA  . VAL A 1 281  ? 166.989 143.496 189.549 1.00 20.69  ? 281  VAL A CA  1 
ATOM 2089 C C   . VAL A 1 281  ? 167.169 141.995 189.350 1.00 15.16  ? 281  VAL A C   1 
ATOM 2090 O O   . VAL A 1 281  ? 168.179 141.539 188.814 1.00 18.95  ? 281  VAL A O   1 
ATOM 2091 C CB  . VAL A 1 281  ? 167.320 144.281 188.281 1.00 19.99  ? 281  VAL A CB  1 
ATOM 2092 C CG1 . VAL A 1 281  ? 166.405 143.871 187.155 1.00 16.57  ? 281  VAL A CG1 1 
ATOM 2093 C CG2 . VAL A 1 281  ? 167.209 145.772 188.548 1.00 15.56  ? 281  VAL A CG2 1 
ATOM 2094 N N   . ALA A 1 282  ? 166.177 141.227 189.789 1.00 15.38  ? 282  ALA A N   1 
ATOM 2095 C CA  . ALA A 1 282  ? 166.139 139.789 189.579 1.00 19.10  ? 282  ALA A CA  1 
ATOM 2096 C C   . ALA A 1 282  ? 164.709 139.386 189.262 1.00 20.58  ? 282  ALA A C   1 
ATOM 2097 O O   . ALA A 1 282  ? 163.768 139.855 189.908 1.00 25.47  ? 282  ALA A O   1 
ATOM 2098 C CB  . ALA A 1 282  ? 166.650 139.025 190.805 1.00 17.51  ? 282  ALA A CB  1 
ATOM 2099 N N   . GLY A 1 283  ? 164.551 138.520 188.270 1.00 10.59  ? 283  GLY A N   1 
ATOM 2100 C CA  . GLY A 1 283  ? 163.242 138.091 187.828 1.00 12.77  ? 283  GLY A CA  1 
ATOM 2101 C C   . GLY A 1 283  ? 162.813 138.784 186.547 1.00 13.09  ? 283  GLY A C   1 
ATOM 2102 O O   . GLY A 1 283  ? 163.396 139.772 186.102 1.00 12.21  ? 283  GLY A O   1 
ATOM 2103 N N   . SER A 1 284  ? 161.751 138.241 185.952 1.00 15.08  ? 284  SER A N   1 
ATOM 2104 C CA  . SER A 1 284  ? 161.299 138.728 184.653 1.00 9.21   ? 284  SER A CA  1 
ATOM 2105 C C   . SER A 1 284  ? 160.711 140.130 184.749 1.00 12.19  ? 284  SER A C   1 
ATOM 2106 O O   . SER A 1 284  ? 160.862 140.932 183.824 1.00 11.00  ? 284  SER A O   1 
ATOM 2107 C CB  . SER A 1 284  ? 160.281 137.759 184.059 1.00 14.61  ? 284  SER A CB  1 
ATOM 2108 O OG  . SER A 1 284  ? 160.880 136.503 183.802 1.00 18.64  ? 284  SER A OG  1 
ATOM 2109 N N   . GLU A 1 285  ? 160.032 140.443 185.854 1.00 13.26  ? 285  GLU A N   1 
ATOM 2110 C CA  . GLU A 1 285  ? 159.370 141.740 185.976 1.00 9.81   ? 285  GLU A CA  1 
ATOM 2111 C C   . GLU A 1 285  ? 160.385 142.872 186.087 1.00 9.56   ? 285  GLU A C   1 
ATOM 2112 O O   . GLU A 1 285  ? 160.295 143.878 185.370 1.00 9.18   ? 285  GLU A O   1 
ATOM 2113 C CB  . GLU A 1 285  ? 158.442 141.732 187.190 1.00 11.10  ? 285  GLU A CB  1 
ATOM 2114 C CG  . GLU A 1 285  ? 157.065 141.169 186.908 1.00 17.74  ? 285  GLU A CG  1 
ATOM 2115 C CD  . GLU A 1 285  ? 156.987 139.680 187.178 1.00 23.76  ? 285  GLU A CD  1 
ATOM 2116 O OE1 . GLU A 1 285  ? 155.862 139.140 187.232 1.00 22.09  ? 285  GLU A OE1 1 
ATOM 2117 O OE2 . GLU A 1 285  ? 158.052 139.049 187.338 1.00 20.42  ? 285  GLU A OE2 1 
ATOM 2118 N N   . ALA A 1 286  ? 161.366 142.722 186.978 1.00 8.65   ? 286  ALA A N   1 
ATOM 2119 C CA  . ALA A 1 286  ? 162.364 143.768 187.162 1.00 2.43   ? 286  ALA A CA  1 
ATOM 2120 C C   . ALA A 1 286  ? 163.281 143.879 185.949 1.00 7.32   ? 286  ALA A C   1 
ATOM 2121 O O   . ALA A 1 286  ? 163.642 144.988 185.533 1.00 9.41   ? 286  ALA A O   1 
ATOM 2122 C CB  . ALA A 1 286  ? 163.165 143.501 188.434 1.00 7.54   ? 286  ALA A CB  1 
ATOM 2123 N N   . LEU A 1 287  ? 163.675 142.741 185.371 1.00 7.50   ? 287  LEU A N   1 
ATOM 2124 C CA  . LEU A 1 287  ? 164.460 142.770 184.142 1.00 3.83   ? 287  LEU A CA  1 
ATOM 2125 C C   . LEU A 1 287  ? 163.691 143.409 182.999 1.00 6.31   ? 287  LEU A C   1 
ATOM 2126 O O   . LEU A 1 287  ? 164.286 144.084 182.156 1.00 8.29   ? 287  LEU A O   1 
ATOM 2127 C CB  . LEU A 1 287  ? 164.890 141.360 183.750 1.00 6.40   ? 287  LEU A CB  1 
ATOM 2128 C CG  . LEU A 1 287  ? 165.865 140.665 184.688 1.00 6.98   ? 287  LEU A CG  1 
ATOM 2129 C CD1 . LEU A 1 287  ? 166.065 139.244 184.233 1.00 13.97  ? 287  LEU A CD1 1 
ATOM 2130 C CD2 . LEU A 1 287  ? 167.172 141.407 184.694 1.00 6.46   ? 287  LEU A CD2 1 
ATOM 2131 N N   . SER A 1 288  ? 162.378 143.192 182.942 1.00 9.94   ? 288  SER A N   1 
ATOM 2132 C CA  . SER A 1 288  ? 161.564 143.825 181.915 1.00 0.99   ? 288  SER A CA  1 
ATOM 2133 C C   . SER A 1 288  ? 161.462 145.325 182.138 1.00 1.90   ? 288  SER A C   1 
ATOM 2134 O O   . SER A 1 288  ? 161.428 146.094 181.171 1.00 14.87  ? 288  SER A O   1 
ATOM 2135 C CB  . SER A 1 288  ? 160.178 143.188 181.898 1.00 3.46   ? 288  SER A CB  1 
ATOM 2136 O OG  . SER A 1 288  ? 160.266 141.825 181.536 1.00 6.30   ? 288  SER A OG  1 
ATOM 2137 N N   . PHE A 1 289  ? 161.396 145.755 183.400 1.00 2.53   ? 289  PHE A N   1 
ATOM 2138 C CA  . PHE A 1 289  ? 161.428 147.184 183.695 1.00 0.97   ? 289  PHE A CA  1 
ATOM 2139 C C   . PHE A 1 289  ? 162.754 147.803 183.266 1.00 2.36   ? 289  PHE A C   1 
ATOM 2140 O O   . PHE A 1 289  ? 162.780 148.902 182.703 1.00 6.29   ? 289  PHE A O   1 
ATOM 2141 C CB  . PHE A 1 289  ? 161.170 147.416 185.185 1.00 4.79   ? 289  PHE A CB  1 
ATOM 2142 C CG  . PHE A 1 289  ? 161.263 148.857 185.605 1.00 2.54   ? 289  PHE A CG  1 
ATOM 2143 C CD1 . PHE A 1 289  ? 162.457 149.386 186.066 1.00 3.11   ? 289  PHE A CD1 1 
ATOM 2144 C CD2 . PHE A 1 289  ? 160.156 149.683 185.533 1.00 3.09   ? 289  PHE A CD2 1 
ATOM 2145 C CE1 . PHE A 1 289  ? 162.544 150.708 186.448 1.00 2.27   ? 289  PHE A CE1 1 
ATOM 2146 C CE2 . PHE A 1 289  ? 160.237 151.006 185.915 1.00 8.33   ? 289  PHE A CE2 1 
ATOM 2147 C CZ  . PHE A 1 289  ? 161.433 151.519 186.373 1.00 10.72  ? 289  PHE A CZ  1 
ATOM 2148 N N   . VAL A 1 290  ? 163.866 147.116 183.530 1.00 6.35   ? 290  VAL A N   1 
ATOM 2149 C CA  . VAL A 1 290  ? 165.168 147.627 183.103 1.00 3.43   ? 290  VAL A CA  1 
ATOM 2150 C C   . VAL A 1 290  ? 165.266 147.654 181.582 1.00 2.39   ? 290  VAL A C   1 
ATOM 2151 O O   . VAL A 1 290  ? 165.815 148.595 180.997 1.00 12.46  ? 290  VAL A O   1 
ATOM 2152 C CB  . VAL A 1 290  ? 166.303 146.800 183.732 1.00 3.95   ? 290  VAL A CB  1 
ATOM 2153 C CG1 . VAL A 1 290  ? 167.628 147.124 183.068 1.00 6.12   ? 290  VAL A CG1 1 
ATOM 2154 C CG2 . VAL A 1 290  ? 166.392 147.089 185.209 1.00 7.53   ? 290  VAL A CG2 1 
ATOM 2155 N N   . ARG A 1 291  ? 164.735 146.625 180.919 1.00 7.40   ? 291  ARG A N   1 
ATOM 2156 C CA  . ARG A 1 291  ? 164.778 146.564 179.462 1.00 2.55   ? 291  ARG A CA  1 
ATOM 2157 C C   . ARG A 1 291  ? 164.045 147.742 178.836 1.00 3.85   ? 291  ARG A C   1 
ATOM 2158 O O   . ARG A 1 291  ? 164.534 148.350 177.878 1.00 13.35  ? 291  ARG A O   1 
ATOM 2159 C CB  . ARG A 1 291  ? 164.174 145.243 178.988 1.00 5.65   ? 291  ARG A CB  1 
ATOM 2160 C CG  . ARG A 1 291  ? 163.977 145.127 177.490 1.00 7.38   ? 291  ARG A CG  1 
ATOM 2161 C CD  . ARG A 1 291  ? 163.094 143.936 177.164 1.00 6.25   ? 291  ARG A CD  1 
ATOM 2162 N NE  . ARG A 1 291  ? 162.732 143.883 175.754 1.00 12.96  ? 291  ARG A NE  1 
ATOM 2163 C CZ  . ARG A 1 291  ? 161.662 144.469 175.235 1.00 14.01  ? 291  ARG A CZ  1 
ATOM 2164 N NH1 . ARG A 1 291  ? 160.832 145.177 175.983 1.00 10.21  ? 291  ARG A NH1 1 
ATOM 2165 N NH2 . ARG A 1 291  ? 161.418 144.341 173.934 1.00 4.05   ? 291  ARG A NH2 1 
ATOM 2166 N N   . ASN A 1 292  ? 162.873 148.082 179.368 1.00 6.48   ? 292  ASN A N   1 
ATOM 2167 C CA  . ASN A 1 292  ? 162.063 149.170 178.824 1.00 0.00   ? 292  ASN A CA  1 
ATOM 2168 C C   . ASN A 1 292  ? 161.157 149.680 179.930 1.00 6.04   ? 292  ASN A C   1 
ATOM 2169 O O   . ASN A 1 292  ? 160.041 149.180 180.124 1.00 11.89  ? 292  ASN A O   1 
ATOM 2170 C CB  . ASN A 1 292  ? 161.254 148.710 177.613 1.00 0.61   ? 292  ASN A CB  1 
ATOM 2171 C CG  . ASN A 1 292  ? 160.399 149.810 177.022 1.00 3.48   ? 292  ASN A CG  1 
ATOM 2172 O OD1 . ASN A 1 292  ? 159.383 149.542 176.390 1.00 4.06   ? 292  ASN A OD1 1 
ATOM 2173 N ND2 . ASN A 1 292  ? 160.810 151.052 177.217 1.00 6.68   ? 292  ASN A ND2 1 
ATOM 2174 N N   . PRO A 1 293  ? 161.610 150.680 180.693 1.00 4.35   ? 293  PRO A N   1 
ATOM 2175 C CA  . PRO A 1 293  ? 160.792 151.194 181.799 1.00 2.58   ? 293  PRO A CA  1 
ATOM 2176 C C   . PRO A 1 293  ? 159.633 152.067 181.357 1.00 2.86   ? 293  PRO A C   1 
ATOM 2177 O O   . PRO A 1 293  ? 158.758 152.365 182.180 1.00 9.11   ? 293  PRO A O   1 
ATOM 2178 C CB  . PRO A 1 293  ? 161.793 152.004 182.637 1.00 1.33   ? 293  PRO A CB  1 
ATOM 2179 C CG  . PRO A 1 293  ? 162.971 152.248 181.763 1.00 1.43   ? 293  PRO A CG  1 
ATOM 2180 C CD  . PRO A 1 293  ? 162.877 151.412 180.528 1.00 0.04   ? 293  PRO A CD  1 
ATOM 2181 N N   . TYR A 1 294  ? 159.592 152.475 180.091 1.00 0.33   ? 294  TYR A N   1 
ATOM 2182 C CA  . TYR A 1 294  ? 158.570 153.409 179.639 1.00 0.00   ? 294  TYR A CA  1 
ATOM 2183 C C   . TYR A 1 294  ? 157.217 152.741 179.423 1.00 2.20   ? 294  TYR A C   1 
ATOM 2184 O O   . TYR A 1 294  ? 156.192 153.430 179.420 1.00 12.05  ? 294  TYR A O   1 
ATOM 2185 C CB  . TYR A 1 294  ? 159.056 154.114 178.374 1.00 0.08   ? 294  TYR A CB  1 
ATOM 2186 C CG  . TYR A 1 294  ? 160.458 154.648 178.539 1.00 0.65   ? 294  TYR A CG  1 
ATOM 2187 C CD1 . TYR A 1 294  ? 160.688 155.837 179.214 1.00 1.37   ? 294  TYR A CD1 1 
ATOM 2188 C CD2 . TYR A 1 294  ? 161.554 153.953 178.049 1.00 2.04   ? 294  TYR A CD2 1 
ATOM 2189 C CE1 . TYR A 1 294  ? 161.963 156.326 179.385 1.00 0.12   ? 294  TYR A CE1 1 
ATOM 2190 C CE2 . TYR A 1 294  ? 162.834 154.436 178.215 1.00 5.24   ? 294  TYR A CE2 1 
ATOM 2191 C CZ  . TYR A 1 294  ? 163.032 155.622 178.884 1.00 3.39   ? 294  TYR A CZ  1 
ATOM 2192 O OH  . TYR A 1 294  ? 164.303 156.110 179.055 1.00 15.59  ? 294  TYR A OH  1 
ATOM 2193 N N   . THR A 1 295  ? 157.181 151.419 179.245 1.00 0.00   ? 295  THR A N   1 
ATOM 2194 C CA  . THR A 1 295  ? 155.896 150.727 179.258 1.00 1.24   ? 295  THR A CA  1 
ATOM 2195 C C   . THR A 1 295  ? 155.372 150.565 180.677 1.00 13.20  ? 295  THR A C   1 
ATOM 2196 O O   . THR A 1 295  ? 154.158 150.593 180.903 1.00 22.22  ? 295  THR A O   1 
ATOM 2197 C CB  . THR A 1 295  ? 156.004 149.364 178.578 1.00 1.12   ? 295  THR A CB  1 
ATOM 2198 O OG1 . THR A 1 295  ? 156.946 148.542 179.279 1.00 4.07   ? 295  THR A OG1 1 
ATOM 2199 C CG2 . THR A 1 295  ? 156.436 149.526 177.156 1.00 6.06   ? 295  THR A CG2 1 
ATOM 2200 N N   . PHE A 1 296  ? 156.271 150.379 181.644 1.00 6.59   ? 296  PHE A N   1 
ATOM 2201 C CA  . PHE A 1 296  ? 155.834 150.238 183.027 1.00 0.00   ? 296  PHE A CA  1 
ATOM 2202 C C   . PHE A 1 296  ? 155.441 151.578 183.631 1.00 3.49   ? 296  PHE A C   1 
ATOM 2203 O O   . PHE A 1 296  ? 154.579 151.623 184.512 1.00 12.70  ? 296  PHE A O   1 
ATOM 2204 C CB  . PHE A 1 296  ? 156.922 149.569 183.871 1.00 2.12   ? 296  PHE A CB  1 
ATOM 2205 C CG  . PHE A 1 296  ? 157.251 148.165 183.443 1.00 3.74   ? 296  PHE A CG  1 
ATOM 2206 C CD1 . PHE A 1 296  ? 157.832 147.910 182.213 1.00 5.18   ? 296  PHE A CD1 1 
ATOM 2207 C CD2 . PHE A 1 296  ? 156.958 147.096 184.271 1.00 5.60   ? 296  PHE A CD2 1 
ATOM 2208 C CE1 . PHE A 1 296  ? 158.122 146.621 181.824 1.00 8.11   ? 296  PHE A CE1 1 
ATOM 2209 C CE2 . PHE A 1 296  ? 157.246 145.805 183.886 1.00 3.44   ? 296  PHE A CE2 1 
ATOM 2210 C CZ  . PHE A 1 296  ? 157.827 145.568 182.662 1.00 5.21   ? 296  PHE A CZ  1 
ATOM 2211 N N   . LEU A 1 297  ? 156.048 152.672 183.176 1.00 5.89   ? 297  LEU A N   1 
ATOM 2212 C CA  . LEU A 1 297  ? 155.730 154.000 183.689 1.00 1.08   ? 297  LEU A CA  1 
ATOM 2213 C C   . LEU A 1 297  ? 154.764 154.766 182.794 1.00 7.41   ? 297  LEU A C   1 
ATOM 2214 O O   . LEU A 1 297  ? 153.700 155.188 183.253 1.00 14.27  ? 297  LEU A O   1 
ATOM 2215 C CB  . LEU A 1 297  ? 157.017 154.808 183.892 1.00 4.68   ? 297  LEU A CB  1 
ATOM 2216 C CG  . LEU A 1 297  ? 158.100 154.100 184.705 1.00 1.84   ? 297  LEU A CG  1 
ATOM 2217 C CD1 . LEU A 1 297  ? 159.408 154.865 184.703 1.00 7.95   ? 297  LEU A CD1 1 
ATOM 2218 C CD2 . LEU A 1 297  ? 157.602 153.930 186.109 1.00 5.29   ? 297  LEU A CD2 1 
ATOM 2219 N N   . GLY A 1 298  ? 155.111 154.959 181.523 1.00 5.58   ? 298  GLY A N   1 
ATOM 2220 C CA  . GLY A 1 298  ? 154.243 155.655 180.605 1.00 4.96   ? 298  GLY A CA  1 
ATOM 2221 C C   . GLY A 1 298  ? 154.998 156.683 179.804 1.00 10.78  ? 298  GLY A C   1 
ATOM 2222 O O   . GLY A 1 298  ? 156.230 156.658 179.730 1.00 14.15  ? 298  GLY A O   1 
ATOM 2223 N N   . GLU A 1 299  ? 154.245 157.605 179.199 1.00 14.95  ? 299  GLU A N   1 
ATOM 2224 C CA  . GLU A 1 299  ? 154.845 158.653 178.384 1.00 14.84  ? 299  GLU A CA  1 
ATOM 2225 C C   . GLU A 1 299  ? 155.442 159.780 179.215 1.00 21.00  ? 299  GLU A C   1 
ATOM 2226 O O   . GLU A 1 299  ? 156.247 160.557 178.691 1.00 26.00  ? 299  GLU A O   1 
ATOM 2227 C CB  . GLU A 1 299  ? 153.809 159.227 177.414 1.00 16.35  ? 299  GLU A CB  1 
ATOM 2228 C CG  . GLU A 1 299  ? 152.808 160.179 178.050 1.00 16.05  ? 299  GLU A CG  1 
ATOM 2229 C CD  . GLU A 1 299  ? 151.691 159.461 178.784 1.00 26.99  ? 299  GLU A CD  1 
ATOM 2230 O OE1 . GLU A 1 299  ? 151.734 158.216 178.877 1.00 24.04  ? 299  GLU A OE1 1 
ATOM 2231 O OE2 . GLU A 1 299  ? 150.766 160.144 179.270 1.00 29.82  ? 299  GLU A OE2 1 
ATOM 2232 N N   . ASP A 1 300  ? 155.068 159.890 180.491 1.00 18.22  ? 300  ASP A N   1 
ATOM 2233 C CA  . ASP A 1 300  ? 155.647 160.911 181.354 1.00 16.30  ? 300  ASP A CA  1 
ATOM 2234 C C   . ASP A 1 300  ? 157.051 160.555 181.819 1.00 16.98  ? 300  ASP A C   1 
ATOM 2235 O O   . ASP A 1 300  ? 157.775 161.436 182.293 1.00 17.40  ? 300  ASP A O   1 
ATOM 2236 C CB  . ASP A 1 300  ? 154.748 161.147 182.570 1.00 16.06  ? 300  ASP A CB  1 
ATOM 2237 C CG  . ASP A 1 300  ? 153.517 161.967 182.235 1.00 27.31  ? 300  ASP A CG  1 
ATOM 2238 O OD1 . ASP A 1 300  ? 153.351 162.339 181.055 1.00 25.25  ? 300  ASP A OD1 1 
ATOM 2239 O OD2 . ASP A 1 300  ? 152.716 162.240 183.153 1.00 30.74  ? 300  ASP A OD2 1 
ATOM 2240 N N   . ALA A 1 301  ? 157.448 159.287 181.693 1.00 14.61  ? 301  ALA A N   1 
ATOM 2241 C CA  . ALA A 1 301  ? 158.776 158.866 182.120 1.00 10.24  ? 301  ALA A CA  1 
ATOM 2242 C C   . ALA A 1 301  ? 159.873 159.336 181.177 1.00 11.66  ? 301  ALA A C   1 
ATOM 2243 O O   . ALA A 1 301  ? 161.032 159.420 181.594 1.00 12.95  ? 301  ALA A O   1 
ATOM 2244 C CB  . ALA A 1 301  ? 158.827 157.346 182.241 1.00 3.68   ? 301  ALA A CB  1 
ATOM 2245 N N   . ALA A 1 302  ? 159.538 159.629 179.919 1.00 9.78   ? 302  ALA A N   1 
ATOM 2246 C CA  . ALA A 1 302  ? 160.556 160.041 178.959 1.00 10.22  ? 302  ALA A CA  1 
ATOM 2247 C C   . ALA A 1 302  ? 161.201 161.358 179.370 1.00 13.59  ? 302  ALA A C   1 
ATOM 2248 O O   . ALA A 1 302  ? 162.404 161.558 179.168 1.00 15.74  ? 302  ALA A O   1 
ATOM 2249 C CB  . ALA A 1 302  ? 159.947 160.150 177.563 1.00 13.77  ? 302  ALA A CB  1 
ATOM 2250 N N   . SER A 1 303  ? 160.413 162.276 179.932 1.00 16.72  ? 303  SER A N   1 
ATOM 2251 C CA  . SER A 1 303  ? 160.980 163.517 180.447 1.00 10.72  ? 303  SER A CA  1 
ATOM 2252 C C   . SER A 1 303  ? 161.882 163.257 181.646 1.00 15.70  ? 303  SER A C   1 
ATOM 2253 O O   . SER A 1 303  ? 162.958 163.854 181.763 1.00 18.88  ? 303  SER A O   1 
ATOM 2254 C CB  . SER A 1 303  ? 159.861 164.487 180.821 1.00 12.41  ? 303  SER A CB  1 
ATOM 2255 O OG  . SER A 1 303  ? 158.980 163.903 181.765 1.00 20.51  ? 303  SER A OG  1 
ATOM 2256 N N   . VAL A 1 304  ? 161.458 162.371 182.549 1.00 9.91   ? 304  VAL A N   1 
ATOM 2257 C CA  . VAL A 1 304  ? 162.248 162.083 183.742 1.00 8.40   ? 304  VAL A CA  1 
ATOM 2258 C C   . VAL A 1 304  ? 163.509 161.312 183.375 1.00 14.40  ? 304  VAL A C   1 
ATOM 2259 O O   . VAL A 1 304  ? 164.608 161.625 183.846 1.00 17.71  ? 304  VAL A O   1 
ATOM 2260 C CB  . VAL A 1 304  ? 161.398 161.316 184.769 1.00 3.95   ? 304  VAL A CB  1 
ATOM 2261 C CG1 . VAL A 1 304  ? 162.237 160.924 185.967 1.00 4.20   ? 304  VAL A CG1 1 
ATOM 2262 C CG2 . VAL A 1 304  ? 160.232 162.144 185.191 1.00 10.88  ? 304  VAL A CG2 1 
ATOM 2263 N N   . ILE A 1 305  ? 163.373 160.296 182.527 1.00 11.64  ? 305  ILE A N   1 
ATOM 2264 C CA  . ILE A 1 305  ? 164.491 159.464 182.100 1.00 8.02   ? 305  ILE A CA  1 
ATOM 2265 C C   . ILE A 1 305  ? 164.601 159.576 180.589 1.00 11.70  ? 305  ILE A C   1 
ATOM 2266 O O   . ILE A 1 305  ? 163.669 159.204 179.867 1.00 16.59  ? 305  ILE A O   1 
ATOM 2267 C CB  . ILE A 1 305  ? 164.306 157.999 182.517 1.00 8.51   ? 305  ILE A CB  1 
ATOM 2268 C CG1 . ILE A 1 305  ? 163.903 157.908 183.983 1.00 8.51   ? 305  ILE A CG1 1 
ATOM 2269 C CG2 . ILE A 1 305  ? 165.582 157.215 182.282 1.00 13.88  ? 305  ILE A CG2 1 
ATOM 2270 C CD1 . ILE A 1 305  ? 163.077 156.700 184.271 1.00 14.16  ? 305  ILE A CD1 1 
ATOM 2271 N N   . ALA A 1 306  ? 165.736 160.069 180.114 1.00 17.06  ? 306  ALA A N   1 
ATOM 2272 C CA  . ALA A 1 306  ? 165.943 160.205 178.678 1.00 13.49  ? 306  ALA A CA  1 
ATOM 2273 C C   . ALA A 1 306  ? 166.150 158.829 178.052 1.00 15.09  ? 306  ALA A C   1 
ATOM 2274 O O   . ALA A 1 306  ? 166.995 158.061 178.530 1.00 12.91  ? 306  ALA A O   1 
ATOM 2275 C CB  . ALA A 1 306  ? 167.142 161.102 178.399 1.00 10.05  ? 306  ALA A CB  1 
ATOM 2276 N N   . PRO A 1 307  ? 165.383 158.467 177.016 1.00 13.05  ? 307  PRO A N   1 
ATOM 2277 C CA  . PRO A 1 307  ? 165.597 157.158 176.380 1.00 11.18  ? 307  PRO A CA  1 
ATOM 2278 C C   . PRO A 1 307  ? 167.033 156.897 175.953 1.00 14.30  ? 307  PRO A C   1 
ATOM 2279 O O   . PRO A 1 307  ? 167.531 155.777 176.129 1.00 11.93  ? 307  PRO A O   1 
ATOM 2280 C CB  . PRO A 1 307  ? 164.662 157.223 175.171 1.00 12.05  ? 307  PRO A CB  1 
ATOM 2281 C CG  . PRO A 1 307  ? 163.509 158.076 175.636 1.00 11.03  ? 307  PRO A CG  1 
ATOM 2282 C CD  . PRO A 1 307  ? 163.998 158.916 176.813 1.00 7.73   ? 307  PRO A CD  1 
ATOM 2283 N N   . GLU A 1 308  ? 167.713 157.899 175.396 1.00 14.74  ? 308  GLU A N   1 
ATOM 2284 C CA  . GLU A 1 308  ? 169.085 157.695 174.946 1.00 13.04  ? 308  GLU A CA  1 
ATOM 2285 C C   . GLU A 1 308  ? 170.023 157.461 176.123 1.00 13.85  ? 308  GLU A C   1 
ATOM 2286 O O   . GLU A 1 308  ? 170.953 156.651 176.034 1.00 15.99  ? 308  GLU A O   1 
ATOM 2287 C CB  . GLU A 1 308  ? 169.550 158.881 174.096 1.00 15.43  ? 308  GLU A CB  1 
ATOM 2288 C CG  . GLU A 1 308  ? 169.572 160.237 174.797 1.00 19.08  ? 308  GLU A CG  1 
ATOM 2289 C CD  . GLU A 1 308  ? 168.191 160.847 174.954 1.00 24.50  ? 308  GLU A CD  1 
ATOM 2290 O OE1 . GLU A 1 308  ? 168.087 161.948 175.534 1.00 21.13  ? 308  GLU A OE1 1 
ATOM 2291 O OE2 . GLU A 1 308  ? 167.207 160.220 174.509 1.00 18.39  ? 308  GLU A OE2 1 
ATOM 2292 N N   . GLU A 1 309  ? 169.791 158.152 177.242 1.00 18.63  ? 309  GLU A N   1 
ATOM 2293 C CA  . GLU A 1 309  ? 170.603 157.908 178.428 1.00 13.13  ? 309  GLU A CA  1 
ATOM 2294 C C   . GLU A 1 309  ? 170.365 156.509 178.982 1.00 9.72   ? 309  GLU A C   1 
ATOM 2295 O O   . GLU A 1 309  ? 171.299 155.862 179.461 1.00 10.52  ? 309  GLU A O   1 
ATOM 2296 C CB  . GLU A 1 309  ? 170.328 158.968 179.493 1.00 12.88  ? 309  GLU A CB  1 
ATOM 2297 C CG  . GLU A 1 309  ? 170.605 160.389 179.035 1.00 13.86  ? 309  GLU A CG  1 
ATOM 2298 C CD  . GLU A 1 309  ? 170.291 161.417 180.103 1.00 22.21  ? 309  GLU A CD  1 
ATOM 2299 O OE1 . GLU A 1 309  ? 170.601 161.163 181.286 1.00 21.32  ? 309  GLU A OE1 1 
ATOM 2300 O OE2 . GLU A 1 309  ? 169.732 162.480 179.760 1.00 21.92  ? 309  GLU A OE2 1 
ATOM 2301 N N   . HIS A 1 310  ? 169.123 156.023 178.926 1.00 12.46  ? 310  HIS A N   1 
ATOM 2302 C CA  . HIS A 1 310  ? 168.857 154.655 179.360 1.00 9.41   ? 310  HIS A CA  1 
ATOM 2303 C C   . HIS A 1 310  ? 169.534 153.645 178.442 1.00 14.19  ? 310  HIS A C   1 
ATOM 2304 O O   . HIS A 1 310  ? 170.068 152.632 178.910 1.00 18.76  ? 310  HIS A O   1 
ATOM 2305 C CB  . HIS A 1 310  ? 167.351 154.402 179.424 1.00 3.26   ? 310  HIS A CB  1 
ATOM 2306 C CG  . HIS A 1 310  ? 166.990 153.051 179.957 1.00 8.51   ? 310  HIS A CG  1 
ATOM 2307 N ND1 . HIS A 1 310  ? 167.232 152.678 181.261 1.00 15.88  ? 310  HIS A ND1 1 
ATOM 2308 C CD2 . HIS A 1 310  ? 166.404 151.985 179.364 1.00 12.21  ? 310  HIS A CD2 1 
ATOM 2309 C CE1 . HIS A 1 310  ? 166.813 151.439 181.448 1.00 9.10   ? 310  HIS A CE1 1 
ATOM 2310 N NE2 . HIS A 1 310  ? 166.306 150.996 180.312 1.00 11.84  ? 310  HIS A NE2 1 
ATOM 2311 N N   . GLU A 1 311  ? 169.523 153.906 177.131 1.00 17.31  ? 311  GLU A N   1 
ATOM 2312 C CA  . GLU A 1 311  ? 170.243 153.048 176.193 1.00 12.98  ? 311  GLU A CA  1 
ATOM 2313 C C   . GLU A 1 311  ? 171.730 153.016 176.518 1.00 14.79  ? 311  GLU A C   1 
ATOM 2314 O O   . GLU A 1 311  ? 172.351 151.945 176.549 1.00 13.90  ? 311  GLU A O   1 
ATOM 2315 C CB  . GLU A 1 311  ? 170.037 153.548 174.764 1.00 12.73  ? 311  GLU A CB  1 
ATOM 2316 C CG  . GLU A 1 311  ? 168.625 153.421 174.244 1.00 14.71  ? 311  GLU A CG  1 
ATOM 2317 C CD  . GLU A 1 311  ? 168.473 153.949 172.835 1.00 19.14  ? 311  GLU A CD  1 
ATOM 2318 O OE1 . GLU A 1 311  ? 169.445 154.529 172.309 1.00 23.90  ? 311  GLU A OE1 1 
ATOM 2319 O OE2 . GLU A 1 311  ? 167.377 153.797 172.259 1.00 21.12  ? 311  GLU A OE2 1 
ATOM 2320 N N   . GLN A 1 312  ? 172.314 154.188 176.768 1.00 18.62  ? 312  GLN A N   1 
ATOM 2321 C CA  . GLN A 1 312  ? 173.732 154.258 177.090 1.00 15.51  ? 312  GLN A CA  1 
ATOM 2322 C C   . GLN A 1 312  ? 174.033 153.539 178.398 1.00 18.88  ? 312  GLN A C   1 
ATOM 2323 O O   . GLN A 1 312  ? 175.054 152.854 178.514 1.00 22.45  ? 312  GLN A O   1 
ATOM 2324 C CB  . GLN A 1 312  ? 174.180 155.717 177.160 1.00 17.80  ? 312  GLN A CB  1 
ATOM 2325 C CG  . GLN A 1 312  ? 175.664 155.896 177.417 1.00 19.48  ? 312  GLN A CG  1 
ATOM 2326 C CD  . GLN A 1 312  ? 176.516 155.308 176.312 1.00 21.80  ? 312  GLN A CD  1 
ATOM 2327 O OE1 . GLN A 1 312  ? 177.117 154.246 176.473 1.00 24.15  ? 312  GLN A OE1 1 
ATOM 2328 N NE2 . GLN A 1 312  ? 176.572 155.997 175.179 1.00 21.32  ? 312  GLN A NE2 1 
ATOM 2329 N N   . ALA A 1 313  ? 173.158 153.684 179.395 1.00 17.62  ? 313  ALA A N   1 
ATOM 2330 C CA  . ALA A 1 313  ? 173.363 153.008 180.671 1.00 18.11  ? 313  ALA A CA  1 
ATOM 2331 C C   . ALA A 1 313  ? 173.287 151.496 180.514 1.00 15.80  ? 313  ALA A C   1 
ATOM 2332 O O   . ALA A 1 313  ? 174.051 150.761 181.150 1.00 18.13  ? 313  ALA A O   1 
ATOM 2333 C CB  . ALA A 1 313  ? 172.338 153.495 181.693 1.00 15.99  ? 313  ALA A CB  1 
ATOM 2334 N N   . LEU A 1 314  ? 172.363 151.014 179.681 1.00 18.74  ? 314  LEU A N   1 
ATOM 2335 C CA  . LEU A 1 314  ? 172.309 149.587 179.388 1.00 17.32  ? 314  LEU A CA  1 
ATOM 2336 C C   . LEU A 1 314  ? 173.583 149.125 178.692 1.00 22.24  ? 314  LEU A C   1 
ATOM 2337 O O   . LEU A 1 314  ? 174.075 148.020 178.950 1.00 25.10  ? 314  LEU A O   1 
ATOM 2338 C CB  . LEU A 1 314  ? 171.083 149.274 178.531 1.00 13.06  ? 314  LEU A CB  1 
ATOM 2339 C CG  . LEU A 1 314  ? 169.736 149.193 179.250 1.00 13.68  ? 314  LEU A CG  1 
ATOM 2340 C CD1 . LEU A 1 314  ? 168.611 148.972 178.254 1.00 14.66  ? 314  LEU A CD1 1 
ATOM 2341 C CD2 . LEU A 1 314  ? 169.748 148.093 180.294 1.00 15.11  ? 314  LEU A CD2 1 
ATOM 2342 N N   . PHE A 1 315  ? 174.125 149.954 177.797 1.00 24.34  ? 315  PHE A N   1 
ATOM 2343 C CA  . PHE A 1 315  ? 175.344 149.575 177.086 1.00 22.16  ? 315  PHE A CA  1 
ATOM 2344 C C   . PHE A 1 315  ? 176.555 149.541 178.016 1.00 24.57  ? 315  PHE A C   1 
ATOM 2345 O O   . PHE A 1 315  ? 177.370 148.615 177.943 1.00 29.57  ? 315  PHE A O   1 
ATOM 2346 C CB  . PHE A 1 315  ? 175.586 150.527 175.914 1.00 21.78  ? 315  PHE A CB  1 
ATOM 2347 C CG  . PHE A 1 315  ? 176.841 150.232 175.141 1.00 29.20  ? 315  PHE A CG  1 
ATOM 2348 C CD1 . PHE A 1 315  ? 178.023 150.894 175.431 1.00 28.64  ? 315  PHE A CD1 1 
ATOM 2349 C CD2 . PHE A 1 315  ? 176.840 149.286 174.130 1.00 27.12  ? 315  PHE A CD2 1 
ATOM 2350 C CE1 . PHE A 1 315  ? 179.177 150.621 174.724 1.00 27.12  ? 315  PHE A CE1 1 
ATOM 2351 C CE2 . PHE A 1 315  ? 177.991 149.009 173.420 1.00 26.96  ? 315  PHE A CE2 1 
ATOM 2352 C CZ  . PHE A 1 315  ? 179.161 149.678 173.717 1.00 25.19  ? 315  PHE A CZ  1 
ATOM 2353 N N   . ASP A 1 316  ? 176.695 150.543 178.890 1.00 21.52  ? 316  ASP A N   1 
ATOM 2354 C CA  . ASP A 1 316  ? 177.833 150.576 179.807 1.00 20.95  ? 316  ASP A CA  1 
ATOM 2355 C C   . ASP A 1 316  ? 177.809 149.396 180.769 1.00 24.15  ? 316  ASP A C   1 
ATOM 2356 O O   . ASP A 1 316  ? 178.857 148.817 181.077 1.00 29.85  ? 316  ASP A O   1 
ATOM 2357 C CB  . ASP A 1 316  ? 177.861 151.891 180.591 1.00 24.63  ? 316  ASP A CB  1 
ATOM 2358 C CG  . ASP A 1 316  ? 178.196 153.087 179.721 1.00 31.54  ? 316  ASP A CG  1 
ATOM 2359 O OD1 . ASP A 1 316  ? 178.915 152.909 178.719 1.00 33.27  ? 316  ASP A OD1 1 
ATOM 2360 O OD2 . ASP A 1 316  ? 177.769 154.213 180.056 1.00 28.05  ? 316  ASP A OD2 1 
ATOM 2361 N N   . ALA A 1 317  ? 176.629 149.031 181.261 1.00 23.67  ? 317  ALA A N   1 
ATOM 2362 C CA  . ALA A 1 317  ? 176.514 147.931 182.208 1.00 21.27  ? 317  ALA A CA  1 
ATOM 2363 C C   . ALA A 1 317  ? 176.541 146.566 181.538 1.00 22.44  ? 317  ALA A C   1 
ATOM 2364 O O   . ALA A 1 317  ? 176.299 145.565 182.216 1.00 29.75  ? 317  ALA A O   1 
ATOM 2365 C CB  . ALA A 1 317  ? 175.233 148.078 183.031 1.00 20.29  ? 317  ALA A CB  1 
ATOM 2366 N N   . ARG A 1 318  ? 176.831 146.509 180.236 1.00 22.53  ? 318  ARG A N   1 
ATOM 2367 C CA  . ARG A 1 318  ? 176.872 145.264 179.471 1.00 25.66  ? 318  ARG A CA  1 
ATOM 2368 C C   . ARG A 1 318  ? 175.595 144.452 179.644 1.00 25.56  ? 318  ARG A C   1 
ATOM 2369 O O   . ARG A 1 318  ? 175.636 143.227 179.708 1.00 26.00  ? 318  ARG A O   1 
ATOM 2370 C CB  . ARG A 1 318  ? 178.101 144.421 179.826 1.00 26.70  ? 318  ARG A CB  1 
ATOM 2371 C CG  . ARG A 1 318  ? 179.409 144.906 179.207 1.00 26.82  ? 318  ARG A CG  1 
ATOM 2372 C CD  . ARG A 1 318  ? 180.035 146.040 180.001 1.00 28.88  ? 318  ARG A CD  1 
ATOM 2373 N NE  . ARG A 1 318  ? 180.295 145.652 181.382 1.00 31.28  ? 318  ARG A NE  1 
ATOM 2374 C CZ  . ARG A 1 318  ? 181.382 145.010 181.789 1.00 32.88  ? 318  ARG A CZ  1 
ATOM 2375 N NH1 . ARG A 1 318  ? 182.338 144.664 180.942 1.00 31.43  ? 318  ARG A NH1 1 
ATOM 2376 N NH2 . ARG A 1 318  ? 181.512 144.707 183.077 1.00 28.46  ? 318  ARG A NH2 1 
ATOM 2377 N N   . ILE A 1 319  ? 174.451 145.132 179.688 1.00 21.00  ? 319  ILE A N   1 
ATOM 2378 C CA  . ILE A 1 319  ? 173.155 144.466 179.831 1.00 17.89  ? 319  ILE A CA  1 
ATOM 2379 C C   . ILE A 1 319  ? 172.599 144.304 178.420 1.00 22.93  ? 319  ILE A C   1 
ATOM 2380 O O   . ILE A 1 319  ? 171.978 145.208 177.860 1.00 23.32  ? 319  ILE A O   1 
ATOM 2381 C CB  . ILE A 1 319  ? 172.211 145.237 180.750 1.00 19.53  ? 319  ILE A CB  1 
ATOM 2382 C CG1 . ILE A 1 319  ? 172.786 145.309 182.166 1.00 17.36  ? 319  ILE A CG1 1 
ATOM 2383 C CG2 . ILE A 1 319  ? 170.842 144.577 180.785 1.00 20.68  ? 319  ILE A CG2 1 
ATOM 2384 C CD1 . ILE A 1 319  ? 172.054 146.263 183.075 1.00 17.61  ? 319  ILE A CD1 1 
ATOM 2385 N N   . PHE A 1 320  ? 172.839 143.135 177.834 1.00 27.52  ? 320  PHE A N   1 
ATOM 2386 C CA  . PHE A 1 320  ? 172.339 142.797 176.509 1.00 25.90  ? 320  PHE A CA  1 
ATOM 2387 C C   . PHE A 1 320  ? 171.351 141.648 176.626 1.00 19.91  ? 320  PHE A C   1 
ATOM 2388 O O   . PHE A 1 320  ? 171.652 140.626 177.251 1.00 19.08  ? 320  PHE A O   1 
ATOM 2389 C CB  . PHE A 1 320  ? 173.480 142.416 175.563 1.00 26.94  ? 320  PHE A CB  1 
ATOM 2390 C CG  . PHE A 1 320  ? 174.617 143.393 175.556 1.00 24.22  ? 320  PHE A CG  1 
ATOM 2391 C CD1 . PHE A 1 320  ? 175.797 143.106 176.219 1.00 20.17  ? 320  PHE A CD1 1 
ATOM 2392 C CD2 . PHE A 1 320  ? 174.505 144.603 174.891 1.00 24.74  ? 320  PHE A CD2 1 
ATOM 2393 C CE1 . PHE A 1 320  ? 176.845 144.002 176.214 1.00 20.85  ? 320  PHE A CE1 1 
ATOM 2394 C CE2 . PHE A 1 320  ? 175.549 145.504 174.886 1.00 24.80  ? 320  PHE A CE2 1 
ATOM 2395 C CZ  . PHE A 1 320  ? 176.720 145.203 175.549 1.00 25.98  ? 320  PHE A CZ  1 
ATOM 2396 N N   . PHE A 1 321  ? 170.175 141.817 176.027 1.00 17.14  ? 321  PHE A N   1 
ATOM 2397 C CA  . PHE A 1 321  ? 169.142 140.783 176.042 1.00 18.93  ? 321  PHE A CA  1 
ATOM 2398 C C   . PHE A 1 321  ? 169.343 139.913 174.809 1.00 22.85  ? 321  PHE A C   1 
ATOM 2399 O O   . PHE A 1 321  ? 168.877 140.223 173.713 1.00 24.47  ? 321  PHE A O   1 
ATOM 2400 C CB  . PHE A 1 321  ? 167.753 141.406 176.100 1.00 19.78  ? 321  PHE A CB  1 
ATOM 2401 C CG  . PHE A 1 321  ? 167.472 142.131 177.388 1.00 21.13  ? 321  PHE A CG  1 
ATOM 2402 C CD1 . PHE A 1 321  ? 168.047 143.363 177.647 1.00 22.18  ? 321  PHE A CD1 1 
ATOM 2403 C CD2 . PHE A 1 321  ? 166.651 141.567 178.349 1.00 19.53  ? 321  PHE A CD2 1 
ATOM 2404 C CE1 . PHE A 1 321  ? 167.799 144.024 178.832 1.00 17.59  ? 321  PHE A CE1 1 
ATOM 2405 C CE2 . PHE A 1 321  ? 166.401 142.223 179.535 1.00 12.63  ? 321  PHE A CE2 1 
ATOM 2406 C CZ  . PHE A 1 321  ? 166.977 143.452 179.777 1.00 16.02  ? 321  PHE A CZ  1 
ATOM 2407 N N   . HIS A 1 322  ? 170.055 138.806 175.000 1.00 26.73  ? 322  HIS A N   1 
ATOM 2408 C CA  . HIS A 1 322  ? 170.450 137.952 173.891 1.00 24.36  ? 322  HIS A CA  1 
ATOM 2409 C C   . HIS A 1 322  ? 169.266 137.149 173.368 1.00 26.56  ? 322  HIS A C   1 
ATOM 2410 O O   . HIS A 1 322  ? 168.423 136.684 174.138 1.00 30.56  ? 322  HIS A O   1 
ATOM 2411 C CB  . HIS A 1 322  ? 171.550 136.988 174.336 1.00 29.17  ? 322  HIS A CB  1 
ATOM 2412 C CG  . HIS A 1 322  ? 172.719 137.656 174.992 1.00 31.23  ? 322  HIS A CG  1 
ATOM 2413 N ND1 . HIS A 1 322  ? 173.544 138.534 174.324 1.00 33.54  ? 322  HIS A ND1 1 
ATOM 2414 C CD2 . HIS A 1 322  ? 173.194 137.584 176.257 1.00 29.24  ? 322  HIS A CD2 1 
ATOM 2415 C CE1 . HIS A 1 322  ? 174.480 138.969 175.148 1.00 33.37  ? 322  HIS A CE1 1 
ATOM 2416 N NE2 . HIS A 1 322  ? 174.290 138.407 176.328 1.00 34.77  ? 322  HIS A NE2 1 
ATOM 2417 N N   . HIS A 1 323  ? 169.206 136.986 172.049 1.00 34.59  ? 323  HIS A N   1 
ATOM 2418 C CA  . HIS A 1 323  ? 168.399 135.920 171.475 1.00 33.38  ? 323  HIS A CA  1 
ATOM 2419 C C   . HIS A 1 323  ? 169.117 134.586 171.629 1.00 34.81  ? 323  HIS A C   1 
ATOM 2420 O O   . HIS A 1 323  ? 170.346 134.504 171.557 1.00 36.47  ? 323  HIS A O   1 
ATOM 2421 C CB  . HIS A 1 323  ? 168.095 136.172 170.000 1.00 33.59  ? 323  HIS A CB  1 
ATOM 2422 C CG  . HIS A 1 323  ? 167.242 137.374 169.749 1.00 36.47  ? 323  HIS A CG  1 
ATOM 2423 N ND1 . HIS A 1 323  ? 167.746 138.656 169.725 1.00 36.52  ? 323  HIS A ND1 1 
ATOM 2424 C CD2 . HIS A 1 323  ? 165.915 137.486 169.509 1.00 35.40  ? 323  HIS A CD2 1 
ATOM 2425 C CE1 . HIS A 1 323  ? 166.764 139.505 169.479 1.00 39.42  ? 323  HIS A CE1 1 
ATOM 2426 N NE2 . HIS A 1 323  ? 165.643 138.822 169.345 1.00 35.71  ? 323  HIS A NE2 1 
ATOM 2427 N N   . PHE A 1 324  ? 168.333 133.535 171.835 1.00 41.57  ? 324  PHE A N   1 
ATOM 2428 C CA  . PHE A 1 324  ? 168.860 132.213 172.125 1.00 44.09  ? 324  PHE A CA  1 
ATOM 2429 C C   . PHE A 1 324  ? 168.290 131.196 171.145 1.00 44.31  ? 324  PHE A C   1 
ATOM 2430 O O   . PHE A 1 324  ? 167.194 131.366 170.605 1.00 42.99  ? 324  PHE A O   1 
ATOM 2431 C CB  . PHE A 1 324  ? 168.538 131.795 173.564 1.00 44.51  ? 324  PHE A CB  1 
ATOM 2432 C CG  . PHE A 1 324  ? 167.101 131.431 173.775 1.00 42.86  ? 324  PHE A CG  1 
ATOM 2433 C CD1 . PHE A 1 324  ? 166.138 132.417 173.897 1.00 39.81  ? 324  PHE A CD1 1 
ATOM 2434 C CD2 . PHE A 1 324  ? 166.710 130.106 173.841 1.00 41.87  ? 324  PHE A CD2 1 
ATOM 2435 C CE1 . PHE A 1 324  ? 164.816 132.089 174.086 1.00 42.57  ? 324  PHE A CE1 1 
ATOM 2436 C CE2 . PHE A 1 324  ? 165.387 129.774 174.029 1.00 43.60  ? 324  PHE A CE2 1 
ATOM 2437 C CZ  . PHE A 1 324  ? 164.442 130.767 174.152 1.00 43.97  ? 324  PHE A CZ  1 
ATOM 2438 N N   . ARG A 1 325  ? 169.058 130.129 170.925 1.00 52.39  ? 325  ARG A N   1 
ATOM 2439 C CA  . ARG A 1 325  ? 168.665 129.039 170.045 1.00 54.40  ? 325  ARG A CA  1 
ATOM 2440 C C   . ARG A 1 325  ? 169.191 127.726 170.608 1.00 57.00  ? 325  ARG A C   1 
ATOM 2441 O O   . ARG A 1 325  ? 170.252 127.682 171.236 1.00 57.42  ? 325  ARG A O   1 
ATOM 2442 C CB  . ARG A 1 325  ? 169.186 129.250 168.615 1.00 55.54  ? 325  ARG A CB  1 
ATOM 2443 C CG  . ARG A 1 325  ? 168.702 128.211 167.614 1.00 57.61  ? 325  ARG A CG  1 
ATOM 2444 C CD  . ARG A 1 325  ? 169.199 128.518 166.214 1.00 57.29  ? 325  ARG A CD  1 
ATOM 2445 N NE  . ARG A 1 325  ? 170.651 128.430 166.130 1.00 60.21  ? 325  ARG A NE  1 
ATOM 2446 C CZ  . ARG A 1 325  ? 171.454 129.460 165.905 1.00 57.86  ? 325  ARG A CZ  1 
ATOM 2447 N NH1 . ARG A 1 325  ? 170.978 130.681 165.732 1.00 55.21  ? 325  ARG A NH1 1 
ATOM 2448 N NH2 . ARG A 1 325  ? 172.768 129.258 165.852 1.00 56.42  ? 325  ARG A NH2 1 
ATOM 2449 N N   . LEU A 1 326  ? 168.435 126.655 170.377 1.00 63.84  ? 326  LEU A N   1 
ATOM 2450 C CA  . LEU A 1 326  ? 168.753 125.326 170.884 1.00 64.10  ? 326  LEU A CA  1 
ATOM 2451 C C   . LEU A 1 326  ? 168.968 124.391 169.702 1.00 66.41  ? 326  LEU A C   1 
ATOM 2452 O O   . LEU A 1 326  ? 168.113 124.304 168.814 1.00 66.36  ? 326  LEU A O   1 
ATOM 2453 C CB  . LEU A 1 326  ? 167.631 124.808 171.784 1.00 63.76  ? 326  LEU A CB  1 
ATOM 2454 C CG  . LEU A 1 326  ? 167.352 125.641 173.035 1.00 63.29  ? 326  LEU A CG  1 
ATOM 2455 C CD1 . LEU A 1 326  ? 166.091 126.465 172.849 1.00 63.97  ? 326  LEU A CD1 1 
ATOM 2456 C CD2 . LEU A 1 326  ? 167.232 124.750 174.254 1.00 64.00  ? 326  LEU A CD2 1 
ATOM 2457 N N   . ILE A 1 327  ? 170.100 123.700 169.689 1.00 71.50  ? 327  ILE A N   1 
ATOM 2458 C CA  . ILE A 1 327  ? 170.492 122.841 168.580 1.00 71.61  ? 327  ILE A CA  1 
ATOM 2459 C C   . ILE A 1 327  ? 170.933 121.494 169.139 1.00 72.77  ? 327  ILE A C   1 
ATOM 2460 O O   . ILE A 1 327  ? 171.996 121.380 169.750 1.00 73.52  ? 327  ILE A O   1 
ATOM 2461 C CB  . ILE A 1 327  ? 171.612 123.477 167.735 1.00 71.83  ? 327  ILE A CB  1 
ATOM 2462 C CG1 . ILE A 1 327  ? 171.147 124.783 167.082 1.00 69.27  ? 327  ILE A CG1 1 
ATOM 2463 C CG2 . ILE A 1 327  ? 172.103 122.495 166.680 1.00 72.14  ? 327  ILE A CG2 1 
ATOM 2464 C CD1 . ILE A 1 327  ? 171.371 126.015 167.933 1.00 69.65  ? 327  ILE A CD1 1 
ATOM 2465 N N   . PRO A 1 328  ? 170.129 120.446 168.962 1.00 81.73  ? 328  PRO A N   1 
ATOM 2466 C CA  . PRO A 1 328  ? 170.634 119.091 169.205 1.00 81.70  ? 328  PRO A CA  1 
ATOM 2467 C C   . PRO A 1 328  ? 171.682 118.705 168.172 1.00 83.10  ? 328  PRO A C   1 
ATOM 2468 O O   . PRO A 1 328  ? 171.673 119.182 167.035 1.00 81.65  ? 328  PRO A O   1 
ATOM 2469 C CB  . PRO A 1 328  ? 169.380 118.218 169.081 1.00 81.95  ? 328  PRO A CB  1 
ATOM 2470 C CG  . PRO A 1 328  ? 168.249 119.143 169.387 1.00 80.99  ? 328  PRO A CG  1 
ATOM 2471 C CD  . PRO A 1 328  ? 168.666 120.468 168.808 1.00 80.66  ? 328  PRO A CD  1 
ATOM 2472 N N   . GLN A 1 329  ? 172.595 117.828 168.581 1.00 89.24  ? 329  GLN A N   1 
ATOM 2473 C CA  . GLN A 1 329  ? 173.641 117.294 167.710 1.00 89.45  ? 329  GLN A CA  1 
ATOM 2474 C C   . GLN A 1 329  ? 173.346 115.812 167.513 1.00 88.28  ? 329  GLN A C   1 
ATOM 2475 O O   . GLN A 1 329  ? 173.766 114.975 168.318 1.00 86.83  ? 329  GLN A O   1 
ATOM 2476 C CB  . GLN A 1 329  ? 175.030 117.521 168.303 1.00 88.19  ? 329  GLN A CB  1 
ATOM 2477 C CG  . GLN A 1 329  ? 175.418 118.983 168.465 1.00 86.47  ? 329  GLN A CG  1 
ATOM 2478 C CD  . GLN A 1 329  ? 174.716 119.649 169.629 1.00 85.52  ? 329  GLN A CD  1 
ATOM 2479 O OE1 . GLN A 1 329  ? 174.190 118.980 170.518 1.00 85.24  ? 329  GLN A OE1 1 
ATOM 2480 N NE2 . GLN A 1 329  ? 174.695 120.972 169.624 1.00 85.27  ? 329  GLN A NE2 1 
ATOM 2481 N N   . LEU A 1 330  ? 172.626 115.496 166.438 1.00 98.52  ? 330  LEU A N   1 
ATOM 2482 C CA  . LEU A 1 330  ? 172.121 114.148 166.216 1.00 100.53 ? 330  LEU A CA  1 
ATOM 2483 C C   . LEU A 1 330  ? 173.254 113.127 166.194 1.00 100.93 ? 330  LEU A C   1 
ATOM 2484 O O   . LEU A 1 330  ? 174.326 113.360 165.631 1.00 99.67  ? 330  LEU A O   1 
ATOM 2485 C CB  . LEU A 1 330  ? 171.335 114.079 164.904 1.00 100.64 ? 330  LEU A CB  1 
ATOM 2486 C CG  . LEU A 1 330  ? 169.863 114.517 164.885 1.00 100.88 ? 330  LEU A CG  1 
ATOM 2487 C CD1 . LEU A 1 330  ? 169.004 113.618 165.765 1.00 99.15  ? 330  LEU A CD1 1 
ATOM 2488 C CD2 . LEU A 1 330  ? 169.689 115.982 165.274 1.00 98.91  ? 330  LEU A CD2 1 
ATOM 2489 N N   . ASN A 1 331  ? 173.002 111.985 166.828 1.00 103.52 ? 331  ASN A N   1 
ATOM 2490 C CA  . ASN A 1 331  ? 173.970 110.904 166.937 1.00 102.93 ? 331  ASN A CA  1 
ATOM 2491 C C   . ASN A 1 331  ? 173.792 110.004 165.710 1.00 103.39 ? 331  ASN A C   1 
ATOM 2492 O O   . ASN A 1 331  ? 173.067 110.345 164.772 1.00 102.42 ? 331  ASN A O   1 
ATOM 2493 C CB  . ASN A 1 331  ? 173.781 110.221 168.299 1.00 101.97 ? 331  ASN A CB  1 
ATOM 2494 C CG  . ASN A 1 331  ? 174.659 108.990 168.512 1.00 102.52 ? 331  ASN A CG  1 
ATOM 2495 O OD1 . ASN A 1 331  ? 175.262 108.455 167.586 1.00 103.29 ? 331  ASN A OD1 1 
ATOM 2496 N ND2 . ASN A 1 331  ? 174.720 108.532 169.756 1.00 102.10 ? 331  ASN A ND2 1 
ATOM 2497 N N   . THR A 1 332  ? 174.463 108.850 165.692 1.00 104.18 ? 332  THR A N   1 
ATOM 2498 C CA  . THR A 1 332  ? 174.406 107.970 164.529 1.00 103.33 ? 332  THR A CA  1 
ATOM 2499 C C   . THR A 1 332  ? 172.994 107.454 164.281 1.00 103.57 ? 332  THR A C   1 
ATOM 2500 O O   . THR A 1 332  ? 172.542 107.383 163.133 1.00 102.10 ? 332  THR A O   1 
ATOM 2501 C CB  . THR A 1 332  ? 175.379 106.804 164.709 1.00 103.18 ? 332  THR A CB  1 
ATOM 2502 O OG1 . THR A 1 332  ? 175.251 106.267 166.032 1.00 103.53 ? 332  THR A OG1 1 
ATOM 2503 C CG2 . THR A 1 332  ? 176.812 107.273 164.496 1.00 102.57 ? 332  THR A CG2 1 
ATOM 2504 N N   . GLU A 1 333  ? 172.285 107.083 165.343 1.00 106.05 ? 333  GLU A N   1 
ATOM 2505 C CA  . GLU A 1 333  ? 170.929 106.563 165.241 1.00 105.44 ? 333  GLU A CA  1 
ATOM 2506 C C   . GLU A 1 333  ? 169.893 107.610 165.666 1.00 105.34 ? 333  GLU A C   1 
ATOM 2507 O O   . GLU A 1 333  ? 168.755 107.269 166.020 1.00 105.16 ? 333  GLU A O   1 
ATOM 2508 C CB  . GLU A 1 333  ? 170.806 105.270 166.059 1.00 104.79 ? 333  GLU A CB  1 
ATOM 2509 C CG  . GLU A 1 333  ? 171.605 104.015 165.561 1.00 104.71 ? 333  GLU A CG  1 
ATOM 2510 C CD  . GLU A 1 333  ? 173.074 103.972 165.983 1.00 105.63 ? 333  GLU A CD  1 
ATOM 2511 O OE1 . GLU A 1 333  ? 173.525 104.870 166.720 1.00 106.52 ? 333  GLU A OE1 1 
ATOM 2512 O OE2 . GLU A 1 333  ? 173.776 103.019 165.573 1.00 104.97 ? 333  GLU A OE2 1 
ATOM 2513 N N   . ASN A 1 334  ? 170.280 108.890 165.629 1.00 103.31 ? 334  ASN A N   1 
ATOM 2514 C CA  . ASN A 1 334  ? 169.426 110.025 165.969 1.00 104.19 ? 334  ASN A CA  1 
ATOM 2515 C C   . ASN A 1 334  ? 169.119 110.057 167.462 1.00 103.68 ? 334  ASN A C   1 
ATOM 2516 O O   . ASN A 1 334  ? 168.291 110.856 167.913 1.00 103.35 ? 334  ASN A O   1 
ATOM 2517 C CB  . ASN A 1 334  ? 168.129 110.000 165.153 1.00 103.64 ? 334  ASN A CB  1 
ATOM 2518 C CG  . ASN A 1 334  ? 168.377 110.150 163.667 1.00 103.22 ? 334  ASN A CG  1 
ATOM 2519 O OD1 . ASN A 1 334  ? 168.842 111.192 163.206 1.00 103.20 ? 334  ASN A OD1 1 
ATOM 2520 N ND2 . ASN A 1 334  ? 168.064 109.108 162.908 1.00 102.02 ? 334  ASN A ND2 1 
ATOM 2521 N N   . LYS A 1 335  ? 169.783 109.200 168.234 1.00 100.45 ? 335  LYS A N   1 
ATOM 2522 C CA  . LYS A 1 335  ? 169.665 109.246 169.683 1.00 100.49 ? 335  LYS A CA  1 
ATOM 2523 C C   . LYS A 1 335  ? 170.282 110.538 170.214 1.00 101.26 ? 335  LYS A C   1 
ATOM 2524 O O   . LYS A 1 335  ? 171.256 111.060 169.670 1.00 100.40 ? 335  LYS A O   1 
ATOM 2525 C CB  . LYS A 1 335  ? 170.346 108.029 170.310 1.00 99.95  ? 335  LYS A CB  1 
ATOM 2526 C CG  . LYS A 1 335  ? 170.207 107.933 171.820 1.00 99.33  ? 335  LYS A CG  1 
ATOM 2527 C CD  . LYS A 1 335  ? 170.862 106.672 172.357 1.00 98.96  ? 335  LYS A CD  1 
ATOM 2528 C CE  . LYS A 1 335  ? 170.641 106.530 173.854 1.00 99.40  ? 335  LYS A CE  1 
ATOM 2529 N NZ  . LYS A 1 335  ? 171.357 107.582 174.625 1.00 99.28  ? 335  LYS A NZ  1 
ATOM 2530 N N   . ILE A 1 336  ? 169.694 111.069 171.284 1.00 97.21  ? 336  ILE A N   1 
ATOM 2531 C CA  . ILE A 1 336  ? 170.076 112.385 171.787 1.00 96.25  ? 336  ILE A CA  1 
ATOM 2532 C C   . ILE A 1 336  ? 170.260 112.328 173.295 1.00 98.03  ? 336  ILE A C   1 
ATOM 2533 O O   . ILE A 1 336  ? 169.301 112.065 174.030 1.00 98.38  ? 336  ILE A O   1 
ATOM 2534 C CB  . ILE A 1 336  ? 169.033 113.460 171.436 1.00 95.27  ? 336  ILE A CB  1 
ATOM 2535 C CG1 . ILE A 1 336  ? 168.847 113.565 169.922 1.00 96.76  ? 336  ILE A CG1 1 
ATOM 2536 C CG2 . ILE A 1 336  ? 169.423 114.804 172.036 1.00 94.31  ? 336  ILE A CG2 1 
ATOM 2537 C CD1 . ILE A 1 336  ? 170.097 113.958 169.190 1.00 96.45  ? 336  ILE A CD1 1 
ATOM 2538 N N   . THR A 1 337  ? 171.493 112.559 173.761 1.00 96.02  ? 337  THR A N   1 
ATOM 2539 C CA  . THR A 1 337  ? 171.718 113.176 175.068 1.00 95.84  ? 337  THR A CA  1 
ATOM 2540 C C   . THR A 1 337  ? 172.774 114.276 174.891 1.00 95.17  ? 337  THR A C   1 
ATOM 2541 O O   . THR A 1 337  ? 173.882 114.206 175.426 1.00 95.49  ? 337  THR A O   1 
ATOM 2542 C CB  . THR A 1 337  ? 172.112 112.094 176.117 1.00 95.53  ? 337  THR A CB  1 
ATOM 2543 O OG1 . THR A 1 337  ? 172.180 112.668 177.430 1.00 94.98  ? 337  THR A OG1 1 
ATOM 2544 C CG2 . THR A 1 337  ? 173.418 111.364 175.753 1.00 95.12  ? 337  THR A CG2 1 
ATOM 2545 N N   . GLU A 1 338  ? 172.371 115.367 174.235 1.00 90.47  ? 338  GLU A N   1 
ATOM 2546 C CA  . GLU A 1 338  ? 173.240 116.492 173.897 1.00 89.46  ? 338  GLU A CA  1 
ATOM 2547 C C   . GLU A 1 338  ? 172.378 117.656 173.434 1.00 90.02  ? 338  GLU A C   1 
ATOM 2548 O O   . GLU A 1 338  ? 171.519 117.476 172.568 1.00 90.67  ? 338  GLU A O   1 
ATOM 2549 C CB  . GLU A 1 338  ? 174.251 116.179 172.773 1.00 89.88  ? 338  GLU A CB  1 
ATOM 2550 C CG  . GLU A 1 338  ? 175.068 114.880 172.812 1.00 89.90  ? 338  GLU A CG  1 
ATOM 2551 C CD  . GLU A 1 338  ? 174.449 113.741 172.008 1.00 90.41  ? 338  GLU A CD  1 
ATOM 2552 O OE1 . GLU A 1 338  ? 173.258 113.425 172.206 1.00 90.71  ? 338  GLU A OE1 1 
ATOM 2553 O OE2 . GLU A 1 338  ? 175.167 113.152 171.170 1.00 91.03  ? 338  GLU A OE2 1 
ATOM 2554 N N   . VAL A 1 339  ? 172.641 118.843 173.980 1.00 78.51  ? 339  VAL A N   1 
ATOM 2555 C CA  . VAL A 1 339  ? 172.028 120.094 173.525 1.00 77.15  ? 339  VAL A CA  1 
ATOM 2556 C C   . VAL A 1 339  ? 173.036 121.214 173.754 1.00 76.42  ? 339  VAL A C   1 
ATOM 2557 O O   . VAL A 1 339  ? 173.813 121.177 174.712 1.00 78.18  ? 339  VAL A O   1 
ATOM 2558 C CB  . VAL A 1 339  ? 170.686 120.378 174.250 1.00 75.20  ? 339  VAL A CB  1 
ATOM 2559 C CG1 . VAL A 1 339  ? 170.149 121.751 173.884 1.00 74.59  ? 339  VAL A CG1 1 
ATOM 2560 C CG2 . VAL A 1 339  ? 169.633 119.355 173.884 1.00 77.30  ? 339  VAL A CG2 1 
ATOM 2561 N N   . THR A 1 340  ? 173.037 122.200 172.859 1.00 69.71  ? 340  THR A N   1 
ATOM 2562 C CA  . THR A 1 340  ? 173.808 123.420 173.039 1.00 68.90  ? 340  THR A CA  1 
ATOM 2563 C C   . THR A 1 340  ? 172.862 124.609 173.137 1.00 69.76  ? 340  THR A C   1 
ATOM 2564 O O   . THR A 1 340  ? 171.685 124.524 172.776 1.00 71.22  ? 340  THR A O   1 
ATOM 2565 C CB  . THR A 1 340  ? 174.794 123.651 171.888 1.00 70.20  ? 340  THR A CB  1 
ATOM 2566 O OG1 . THR A 1 340  ? 175.596 124.804 172.172 1.00 68.81  ? 340  THR A OG1 1 
ATOM 2567 C CG2 . THR A 1 340  ? 174.039 123.895 170.594 1.00 69.64  ? 340  THR A CG2 1 
ATOM 2568 N N   . LEU A 1 341  ? 173.388 125.726 173.636 1.00 60.13  ? 341  LEU A N   1 
ATOM 2569 C CA  . LEU A 1 341  ? 172.637 126.972 173.715 1.00 58.54  ? 341  LEU A CA  1 
ATOM 2570 C C   . LEU A 1 341  ? 173.506 128.099 173.177 1.00 58.33  ? 341  LEU A C   1 
ATOM 2571 O O   . LEU A 1 341  ? 174.598 128.345 173.699 1.00 61.01  ? 341  LEU A O   1 
ATOM 2572 C CB  . LEU A 1 341  ? 172.192 127.263 175.151 1.00 56.48  ? 341  LEU A CB  1 
ATOM 2573 C CG  . LEU A 1 341  ? 171.704 128.682 175.438 1.00 57.07  ? 341  LEU A CG  1 
ATOM 2574 C CD1 . LEU A 1 341  ? 170.477 128.985 174.605 1.00 59.53  ? 341  LEU A CD1 1 
ATOM 2575 C CD2 . LEU A 1 341  ? 171.393 128.848 176.913 1.00 56.94  ? 341  LEU A CD2 1 
ATOM 2576 N N   . ILE A 1 342  ? 173.022 128.778 172.141 1.00 50.89  ? 342  ILE A N   1 
ATOM 2577 C CA  . ILE A 1 342  ? 173.740 129.867 171.488 1.00 52.31  ? 342  ILE A CA  1 
ATOM 2578 C C   . ILE A 1 342  ? 173.013 131.167 171.795 1.00 52.52  ? 342  ILE A C   1 
ATOM 2579 O O   . ILE A 1 342  ? 171.803 131.274 171.567 1.00 53.29  ? 342  ILE A O   1 
ATOM 2580 C CB  . ILE A 1 342  ? 173.836 129.646 169.968 1.00 54.08  ? 342  ILE A CB  1 
ATOM 2581 C CG1 . ILE A 1 342  ? 174.553 128.333 169.654 1.00 53.97  ? 342  ILE A CG1 1 
ATOM 2582 C CG2 . ILE A 1 342  ? 174.556 130.810 169.306 1.00 52.00  ? 342  ILE A CG2 1 
ATOM 2583 C CD1 . ILE A 1 342  ? 175.965 128.280 170.161 1.00 53.32  ? 342  ILE A CD1 1 
ATOM 2584 N N   . LEU A 1 343  ? 173.745 132.154 172.306 1.00 44.44  ? 343  LEU A N   1 
ATOM 2585 C CA  . LEU A 1 343  ? 173.189 133.468 172.616 1.00 42.70  ? 343  LEU A CA  1 
ATOM 2586 C C   . LEU A 1 343  ? 173.801 134.496 171.673 1.00 43.05  ? 343  LEU A C   1 
ATOM 2587 O O   . LEU A 1 343  ? 174.926 134.955 171.896 1.00 50.05  ? 343  LEU A O   1 
ATOM 2588 C CB  . LEU A 1 343  ? 173.453 133.859 174.068 1.00 46.93  ? 343  LEU A CB  1 
ATOM 2589 C CG  . LEU A 1 343  ? 173.026 132.935 175.207 1.00 45.64  ? 343  LEU A CG  1 
ATOM 2590 C CD1 . LEU A 1 343  ? 173.894 133.212 176.415 1.00 46.68  ? 343  LEU A CD1 1 
ATOM 2591 C CD2 . LEU A 1 343  ? 171.561 133.119 175.550 1.00 44.19  ? 343  LEU A CD2 1 
ATOM 2592 N N   . GLU A 1 344  ? 173.063 134.866 170.629 1.00 39.07  ? 344  GLU A N   1 
ATOM 2593 C CA  . GLU A 1 344  ? 173.496 135.947 169.753 1.00 40.84  ? 344  GLU A CA  1 
ATOM 2594 C C   . GLU A 1 344  ? 173.004 137.279 170.309 1.00 42.45  ? 344  GLU A C   1 
ATOM 2595 O O   . GLU A 1 344  ? 171.796 137.440 170.529 1.00 41.79  ? 344  GLU A O   1 
ATOM 2596 C CB  . GLU A 1 344  ? 173.018 135.719 168.321 1.00 44.63  ? 344  GLU A CB  1 
ATOM 2597 C CG  . GLU A 1 344  ? 171.525 135.825 168.059 1.00 42.19  ? 344  GLU A CG  1 
ATOM 2598 C CD  . GLU A 1 344  ? 170.796 134.530 168.351 1.00 44.77  ? 344  GLU A CD  1 
ATOM 2599 O OE1 . GLU A 1 344  ? 171.380 133.660 169.029 1.00 48.91  ? 344  GLU A OE1 1 
ATOM 2600 O OE2 . GLU A 1 344  ? 169.644 134.375 167.895 1.00 45.81  ? 344  GLU A OE2 1 
ATOM 2601 N N   . PRO A 1 345  ? 173.894 138.223 170.602 1.00 47.06  ? 345  PRO A N   1 
ATOM 2602 C CA  . PRO A 1 345  ? 173.483 139.430 171.327 1.00 46.19  ? 345  PRO A CA  1 
ATOM 2603 C C   . PRO A 1 345  ? 172.707 140.409 170.462 1.00 42.90  ? 345  PRO A C   1 
ATOM 2604 O O   . PRO A 1 345  ? 172.801 140.406 169.233 1.00 43.03  ? 345  PRO A O   1 
ATOM 2605 C CB  . PRO A 1 345  ? 174.817 140.044 171.777 1.00 46.67  ? 345  PRO A CB  1 
ATOM 2606 C CG  . PRO A 1 345  ? 175.811 138.927 171.686 1.00 44.82  ? 345  PRO A CG  1 
ATOM 2607 C CD  . PRO A 1 345  ? 175.357 138.102 170.525 1.00 45.05  ? 345  PRO A CD  1 
ATOM 2608 N N   . VAL A 1 346  ? 171.933 141.257 171.133 1.00 38.74  ? 346  VAL A N   1 
ATOM 2609 C CA  . VAL A 1 346  ? 171.353 142.451 170.520 1.00 46.91  ? 346  VAL A CA  1 
ATOM 2610 C C   . VAL A 1 346  ? 172.222 143.610 170.995 1.00 48.94  ? 346  VAL A C   1 
ATOM 2611 O O   . VAL A 1 346  ? 172.141 144.054 172.143 1.00 48.20  ? 346  VAL A O   1 
ATOM 2612 C CB  . VAL A 1 346  ? 169.883 142.636 170.887 1.00 48.03  ? 346  VAL A CB  1 
ATOM 2613 C CG1 . VAL A 1 346  ? 169.429 144.056 170.574 1.00 42.11  ? 346  VAL A CG1 1 
ATOM 2614 C CG2 . VAL A 1 346  ? 169.035 141.646 170.137 1.00 42.11  ? 346  VAL A CG2 1 
ATOM 2615 N N   . SER A 1 347  ? 173.073 144.095 170.105 1.00 47.00  ? 347  SER A N   1 
ATOM 2616 C CA  . SER A 1 347  ? 174.066 145.114 170.440 1.00 46.34  ? 347  SER A CA  1 
ATOM 2617 C C   . SER A 1 347  ? 174.177 146.129 169.290 1.00 47.72  ? 347  SER A C   1 
ATOM 2618 O O   . SER A 1 347  ? 173.798 145.828 168.174 1.00 49.42  ? 347  SER A O   1 
ATOM 2619 C CB  . SER A 1 347  ? 175.438 144.482 170.675 1.00 44.96  ? 347  SER A CB  1 
ATOM 2620 O OG  . SER A 1 347  ? 175.412 143.643 171.815 1.00 45.63  ? 347  SER A OG  1 
ATOM 2621 N N   . PRO A 1 348  ? 174.751 147.302 169.557 1.00 51.31  ? 348  PRO A N   1 
ATOM 2622 C CA  . PRO A 1 348  ? 174.897 148.254 168.443 1.00 47.14  ? 348  PRO A CA  1 
ATOM 2623 C C   . PRO A 1 348  ? 176.075 147.837 167.558 1.00 47.60  ? 348  PRO A C   1 
ATOM 2624 O O   . PRO A 1 348  ? 176.125 148.188 166.369 1.00 47.87  ? 348  PRO A O   1 
ATOM 2625 C CB  . PRO A 1 348  ? 175.190 149.563 169.198 1.00 47.64  ? 348  PRO A CB  1 
ATOM 2626 C CG  . PRO A 1 348  ? 174.700 148.991 170.591 1.00 46.74  ? 348  PRO A CG  1 
ATOM 2627 C CD  . PRO A 1 348  ? 175.542 147.993 170.580 1.00 46.99  ? 348  PRO A CD  1 
ATOM 2628 N N   . VAL A 1 349  ? 177.038 147.107 168.108 1.00 52.06  ? 349  VAL A N   1 
ATOM 2629 C CA  . VAL A 1 349  ? 178.198 146.602 167.380 1.00 54.74  ? 349  VAL A CA  1 
ATOM 2630 C C   . VAL A 1 349  ? 178.183 145.084 167.460 1.00 54.50  ? 349  VAL A C   1 
ATOM 2631 O O   . VAL A 1 349  ? 177.849 144.532 168.512 1.00 53.76  ? 349  VAL A O   1 
ATOM 2632 C CB  . VAL A 1 349  ? 179.530 147.161 167.920 1.00 54.21  ? 349  VAL A CB  1 
ATOM 2633 C CG1 . VAL A 1 349  ? 179.795 146.688 169.344 1.00 52.29  ? 349  VAL A CG1 1 
ATOM 2634 C CG2 . VAL A 1 349  ? 180.682 146.778 167.001 1.00 52.74  ? 349  VAL A CG2 1 
ATOM 2635 N N   . PRO A 1 350  ? 178.459 144.372 166.368 1.00 49.23  ? 350  PRO A N   1 
ATOM 2636 C CA  . PRO A 1 350  ? 178.563 142.913 166.437 1.00 50.00  ? 350  PRO A CA  1 
ATOM 2637 C C   . PRO A 1 350  ? 179.585 142.466 167.469 1.00 52.73  ? 350  PRO A C   1 
ATOM 2638 O O   . PRO A 1 350  ? 180.669 143.040 167.587 1.00 52.50  ? 350  PRO A O   1 
ATOM 2639 C CB  . PRO A 1 350  ? 178.999 142.535 165.014 1.00 49.66  ? 350  PRO A CB  1 
ATOM 2640 C CG  . PRO A 1 350  ? 178.878 143.849 164.185 1.00 50.15  ? 350  PRO A CG  1 
ATOM 2641 C CD  . PRO A 1 350  ? 178.045 144.764 165.015 1.00 47.20  ? 350  PRO A CD  1 
ATOM 2642 N N   . GLN A 1 351  ? 179.225 141.429 168.217 1.00 59.49  ? 351  GLN A N   1 
ATOM 2643 C CA  . GLN A 1 351  ? 180.086 140.854 169.236 1.00 59.58  ? 351  GLN A CA  1 
ATOM 2644 C C   . GLN A 1 351  ? 180.052 139.338 169.125 1.00 60.91  ? 351  GLN A C   1 
ATOM 2645 O O   . GLN A 1 351  ? 179.064 138.771 168.643 1.00 58.00  ? 351  GLN A O   1 
ATOM 2646 C CB  . GLN A 1 351  ? 179.656 141.273 170.652 1.00 55.99  ? 351  GLN A CB  1 
ATOM 2647 C CG  . GLN A 1 351  ? 179.610 142.774 170.883 1.00 58.24  ? 351  GLN A CG  1 
ATOM 2648 C CD  . GLN A 1 351  ? 178.783 143.146 172.098 1.00 58.77  ? 351  GLN A CD  1 
ATOM 2649 O OE1 . GLN A 1 351  ? 178.019 142.332 172.615 1.00 56.45  ? 351  GLN A OE1 1 
ATOM 2650 N NE2 . GLN A 1 351  ? 178.935 144.381 172.562 1.00 57.85  ? 351  GLN A NE2 1 
ATOM 2651 N N   . PRO A 1 352  ? 181.119 138.659 169.549 1.00 69.49  ? 352  PRO A N   1 
ATOM 2652 C CA  . PRO A 1 352  ? 181.096 137.192 169.561 1.00 68.26  ? 352  PRO A CA  1 
ATOM 2653 C C   . PRO A 1 352  ? 179.998 136.662 170.472 1.00 68.27  ? 352  PRO A C   1 
ATOM 2654 O O   . PRO A 1 352  ? 179.691 137.245 171.515 1.00 66.94  ? 352  PRO A O   1 
ATOM 2655 C CB  . PRO A 1 352  ? 182.490 136.821 170.080 1.00 66.74  ? 352  PRO A CB  1 
ATOM 2656 C CG  . PRO A 1 352  ? 183.340 138.000 169.733 1.00 66.47  ? 352  PRO A CG  1 
ATOM 2657 C CD  . PRO A 1 352  ? 182.445 139.191 169.905 1.00 67.31  ? 352  PRO A CD  1 
ATOM 2658 N N   . GLU A 1 353  ? 179.405 135.547 170.062 1.00 65.07  ? 353  GLU A N   1 
ATOM 2659 C CA  . GLU A 1 353  ? 178.286 134.956 170.776 1.00 64.07  ? 353  GLU A CA  1 
ATOM 2660 C C   . GLU A 1 353  ? 178.771 134.155 171.985 1.00 63.77  ? 353  GLU A C   1 
ATOM 2661 O O   . GLU A 1 353  ? 179.953 133.823 172.115 1.00 62.03  ? 353  GLU A O   1 
ATOM 2662 C CB  . GLU A 1 353  ? 177.468 134.071 169.831 1.00 61.55  ? 353  GLU A CB  1 
ATOM 2663 C CG  . GLU A 1 353  ? 178.171 132.798 169.375 1.00 63.88  ? 353  GLU A CG  1 
ATOM 2664 C CD  . GLU A 1 353  ? 179.073 133.019 168.175 1.00 65.31  ? 353  GLU A CD  1 
ATOM 2665 O OE1 . GLU A 1 353  ? 179.393 134.188 167.878 1.00 64.65  ? 353  GLU A OE1 1 
ATOM 2666 O OE2 . GLU A 1 353  ? 179.462 132.022 167.529 1.00 65.09  ? 353  GLU A OE2 1 
ATOM 2667 N N   . ILE A 1 354  ? 177.834 133.854 172.881 1.00 60.55  ? 354  ILE A N   1 
ATOM 2668 C CA  . ILE A 1 354  ? 178.107 133.098 174.099 1.00 58.86  ? 354  ILE A CA  1 
ATOM 2669 C C   . ILE A 1 354  ? 177.474 131.721 173.961 1.00 57.67  ? 354  ILE A C   1 
ATOM 2670 O O   . ILE A 1 354  ? 176.286 131.605 173.638 1.00 57.61  ? 354  ILE A O   1 
ATOM 2671 C CB  . ILE A 1 354  ? 177.577 133.825 175.347 1.00 56.74  ? 354  ILE A CB  1 
ATOM 2672 C CG1 . ILE A 1 354  ? 178.279 135.173 175.542 1.00 57.04  ? 354  ILE A CG1 1 
ATOM 2673 C CG2 . ILE A 1 354  ? 177.754 132.954 176.579 1.00 57.05  ? 354  ILE A CG2 1 
ATOM 2674 C CD1 . ILE A 1 354  ? 177.617 136.340 174.832 1.00 55.32  ? 354  ILE A CD1 1 
ATOM 2675 N N   . THR A 1 355  ? 178.262 130.679 174.213 1.00 62.53  ? 355  THR A N   1 
ATOM 2676 C CA  . THR A 1 355  ? 177.846 129.302 173.995 1.00 63.69  ? 355  THR A CA  1 
ATOM 2677 C C   . THR A 1 355  ? 177.734 128.557 175.317 1.00 63.26  ? 355  THR A C   1 
ATOM 2678 O O   . THR A 1 355  ? 178.619 128.650 176.173 1.00 63.33  ? 355  THR A O   1 
ATOM 2679 C CB  . THR A 1 355  ? 178.832 128.565 173.081 1.00 64.04  ? 355  THR A CB  1 
ATOM 2680 O OG1 . THR A 1 355  ? 179.119 129.371 171.931 1.00 63.53  ? 355  THR A OG1 1 
ATOM 2681 C CG2 . THR A 1 355  ? 178.263 127.221 172.643 1.00 62.50  ? 355  THR A CG2 1 
ATOM 2682 N N   . PHE A 1 356  ? 176.639 127.821 175.471 1.00 63.76  ? 356  PHE A N   1 
ATOM 2683 C CA  . PHE A 1 356  ? 176.462 126.857 176.543 1.00 64.11  ? 356  PHE A CA  1 
ATOM 2684 C C   . PHE A 1 356  ? 176.344 125.457 175.961 1.00 66.98  ? 356  PHE A C   1 
ATOM 2685 O O   . PHE A 1 356  ? 175.973 125.268 174.800 1.00 69.63  ? 356  PHE A O   1 
ATOM 2686 C CB  . PHE A 1 356  ? 175.221 127.165 177.386 1.00 62.35  ? 356  PHE A CB  1 
ATOM 2687 C CG  . PHE A 1 356  ? 175.318 128.432 178.178 1.00 64.65  ? 356  PHE A CG  1 
ATOM 2688 C CD1 . PHE A 1 356  ? 176.005 128.458 179.378 1.00 63.92  ? 356  PHE A CD1 1 
ATOM 2689 C CD2 . PHE A 1 356  ? 174.707 129.591 177.737 1.00 66.93  ? 356  PHE A CD2 1 
ATOM 2690 C CE1 . PHE A 1 356  ? 176.091 129.619 180.119 1.00 67.10  ? 356  PHE A CE1 1 
ATOM 2691 C CE2 . PHE A 1 356  ? 174.789 130.752 178.476 1.00 65.82  ? 356  PHE A CE2 1 
ATOM 2692 C CZ  . PHE A 1 356  ? 175.482 130.767 179.666 1.00 65.27  ? 356  PHE A CZ  1 
ATOM 2693 N N   . VAL A 1 357  ? 176.668 124.471 176.788 1.00 71.85  ? 357  VAL A N   1 
ATOM 2694 C CA  . VAL A 1 357  ? 176.543 123.068 176.423 1.00 71.67  ? 357  VAL A CA  1 
ATOM 2695 C C   . VAL A 1 357  ? 175.625 122.414 177.442 1.00 71.21  ? 357  VAL A C   1 
ATOM 2696 O O   . VAL A 1 357  ? 175.975 122.320 178.624 1.00 72.03  ? 357  VAL A O   1 
ATOM 2697 C CB  . VAL A 1 357  ? 177.906 122.356 176.387 1.00 71.14  ? 357  VAL A CB  1 
ATOM 2698 C CG1 . VAL A 1 357  ? 177.725 120.876 176.106 1.00 71.59  ? 357  VAL A CG1 1 
ATOM 2699 C CG2 . VAL A 1 357  ? 178.816 122.993 175.347 1.00 69.81  ? 357  VAL A CG2 1 
ATOM 2700 N N   . PHE A 1 358  ? 174.452 121.971 176.995 1.00 71.80  ? 358  PHE A N   1 
ATOM 2701 C CA  . PHE A 1 358  ? 173.517 121.251 177.859 1.00 71.00  ? 358  PHE A CA  1 
ATOM 2702 C C   . PHE A 1 358  ? 173.729 119.759 177.623 1.00 73.81  ? 358  PHE A C   1 
ATOM 2703 O O   . PHE A 1 358  ? 173.058 119.131 176.802 1.00 74.40  ? 358  PHE A O   1 
ATOM 2704 C CB  . PHE A 1 358  ? 172.079 121.682 177.601 1.00 72.15  ? 358  PHE A CB  1 
ATOM 2705 C CG  . PHE A 1 358  ? 171.768 123.061 178.100 1.00 72.44  ? 358  PHE A CG  1 
ATOM 2706 C CD1 . PHE A 1 358  ? 170.890 123.879 177.416 1.00 71.59  ? 358  PHE A CD1 1 
ATOM 2707 C CD2 . PHE A 1 358  ? 172.357 123.538 179.259 1.00 72.26  ? 358  PHE A CD2 1 
ATOM 2708 C CE1 . PHE A 1 358  ? 170.603 125.147 177.873 1.00 69.56  ? 358  PHE A CE1 1 
ATOM 2709 C CE2 . PHE A 1 358  ? 172.073 124.806 179.720 1.00 70.77  ? 358  PHE A CE2 1 
ATOM 2710 C CZ  . PHE A 1 358  ? 171.195 125.611 179.026 1.00 69.28  ? 358  PHE A CZ  1 
ATOM 2711 N N   . SER A 1 359  ? 174.685 119.199 178.364 1.00 80.69  ? 359  SER A N   1 
ATOM 2712 C CA  . SER A 1 359  ? 175.066 117.798 178.260 1.00 81.55  ? 359  SER A CA  1 
ATOM 2713 C C   . SER A 1 359  ? 174.132 116.858 179.012 1.00 82.30  ? 359  SER A C   1 
ATOM 2714 O O   . SER A 1 359  ? 174.191 115.645 178.782 1.00 81.05  ? 359  SER A O   1 
ATOM 2715 C CB  . SER A 1 359  ? 176.496 117.620 178.778 1.00 79.56  ? 359  SER A CB  1 
ATOM 2716 O OG  . SER A 1 359  ? 176.628 118.153 180.086 1.00 79.30  ? 359  SER A OG  1 
ATOM 2717 N N   . ALA A 1 360  ? 173.281 117.375 179.895 1.00 81.60  ? 360  ALA A N   1 
ATOM 2718 C CA  . ALA A 1 360  ? 172.375 116.559 180.688 1.00 80.20  ? 360  ALA A CA  1 
ATOM 2719 C C   . ALA A 1 360  ? 170.962 117.118 180.617 1.00 81.51  ? 360  ALA A C   1 
ATOM 2720 O O   . ALA A 1 360  ? 170.773 118.318 180.402 1.00 82.52  ? 360  ALA A O   1 
ATOM 2721 C CB  . ALA A 1 360  ? 172.831 116.489 182.153 1.00 81.20  ? 360  ALA A CB  1 
ATOM 2722 N N   . PRO A 1 361  ? 169.947 116.263 180.769 1.00 79.09  ? 361  PRO A N   1 
ATOM 2723 C CA  . PRO A 1 361  ? 168.558 116.745 180.667 1.00 77.93  ? 361  PRO A CA  1 
ATOM 2724 C C   . PRO A 1 361  ? 168.126 117.682 181.786 1.00 77.92  ? 361  PRO A C   1 
ATOM 2725 O O   . PRO A 1 361  ? 167.252 118.522 181.550 1.00 78.16  ? 361  PRO A O   1 
ATOM 2726 C CB  . PRO A 1 361  ? 167.735 115.448 180.685 1.00 78.11  ? 361  PRO A CB  1 
ATOM 2727 C CG  . PRO A 1 361  ? 168.681 114.389 180.245 1.00 78.94  ? 361  PRO A CG  1 
ATOM 2728 C CD  . PRO A 1 361  ? 170.014 114.793 180.800 1.00 78.12  ? 361  PRO A CD  1 
ATOM 2729 N N   . TRP A 1 362  ? 168.689 117.561 182.994 1.00 80.19  ? 362  TRP A N   1 
ATOM 2730 C CA  . TRP A 1 362  ? 168.212 118.361 184.123 1.00 78.73  ? 362  TRP A CA  1 
ATOM 2731 C C   . TRP A 1 362  ? 168.550 119.838 183.956 1.00 78.22  ? 362  TRP A C   1 
ATOM 2732 O O   . TRP A 1 362  ? 167.754 120.712 184.319 1.00 77.16  ? 362  TRP A O   1 
ATOM 2733 C CB  . TRP A 1 362  ? 168.794 117.825 185.433 1.00 78.63  ? 362  TRP A CB  1 
ATOM 2734 C CG  . TRP A 1 362  ? 170.293 117.933 185.544 1.00 80.18  ? 362  TRP A CG  1 
ATOM 2735 C CD1 . TRP A 1 362  ? 171.212 117.044 185.071 1.00 79.45  ? 362  TRP A CD1 1 
ATOM 2736 C CD2 . TRP A 1 362  ? 171.041 118.978 186.183 1.00 80.98  ? 362  TRP A CD2 1 
ATOM 2737 N NE1 . TRP A 1 362  ? 172.484 117.472 185.366 1.00 79.22  ? 362  TRP A NE1 1 
ATOM 2738 C CE2 . TRP A 1 362  ? 172.407 118.657 186.049 1.00 80.76  ? 362  TRP A CE2 1 
ATOM 2739 C CE3 . TRP A 1 362  ? 170.688 120.155 186.851 1.00 79.50  ? 362  TRP A CE3 1 
ATOM 2740 C CZ2 . TRP A 1 362  ? 173.419 119.469 186.558 1.00 79.85  ? 362  TRP A CZ2 1 
ATOM 2741 C CZ3 . TRP A 1 362  ? 171.696 120.960 187.355 1.00 79.10  ? 362  TRP A CZ3 1 
ATOM 2742 C CH2 . TRP A 1 362  ? 173.044 120.613 187.206 1.00 79.86  ? 362  TRP A CH2 1 
ATOM 2743 N N   . GLU A 1 363  ? 169.734 120.136 183.429 1.00 74.71  ? 363  GLU A N   1 
ATOM 2744 C CA  . GLU A 1 363  ? 170.124 121.525 183.199 1.00 76.29  ? 363  GLU A CA  1 
ATOM 2745 C C   . GLU A 1 363  ? 169.290 122.171 182.092 1.00 74.41  ? 363  GLU A C   1 
ATOM 2746 O O   . GLU A 1 363  ? 168.884 123.340 182.203 1.00 75.59  ? 363  GLU A O   1 
ATOM 2747 C CB  . GLU A 1 363  ? 171.632 121.552 182.936 1.00 76.46  ? 363  GLU A CB  1 
ATOM 2748 C CG  . GLU A 1 363  ? 172.089 120.633 181.818 1.00 76.25  ? 363  GLU A CG  1 
ATOM 2749 C CD  . GLU A 1 363  ? 173.588 120.426 181.820 1.00 77.19  ? 363  GLU A CD  1 
ATOM 2750 O OE1 . GLU A 1 363  ? 174.319 121.353 182.217 1.00 77.40  ? 363  GLU A OE1 1 
ATOM 2751 O OE2 . GLU A 1 363  ? 174.030 119.305 181.489 1.00 76.84  ? 363  GLU A OE2 1 
ATOM 2752 N N   . LEU A 1 364  ? 168.972 121.412 181.041 1.00 65.75  ? 364  LEU A N   1 
ATOM 2753 C CA  . LEU A 1 364  ? 168.006 121.895 180.059 1.00 65.54  ? 364  LEU A CA  1 
ATOM 2754 C C   . LEU A 1 364  ? 166.636 122.098 180.691 1.00 63.94  ? 364  LEU A C   1 
ATOM 2755 O O   . LEU A 1 364  ? 165.946 123.066 180.375 1.00 64.09  ? 364  LEU A O   1 
ATOM 2756 C CB  . LEU A 1 364  ? 167.903 120.929 178.883 1.00 67.36  ? 364  LEU A CB  1 
ATOM 2757 C CG  . LEU A 1 364  ? 166.941 121.461 177.820 1.00 64.61  ? 364  LEU A CG  1 
ATOM 2758 C CD1 . LEU A 1 364  ? 167.475 122.767 177.259 1.00 64.86  ? 364  LEU A CD1 1 
ATOM 2759 C CD2 . LEU A 1 364  ? 166.679 120.447 176.724 1.00 65.95  ? 364  LEU A CD2 1 
ATOM 2760 N N   . ASP A 1 365  ? 166.224 121.193 181.583 1.00 63.88  ? 365  ASP A N   1 
ATOM 2761 C CA  . ASP A 1 365  ? 164.950 121.353 182.278 1.00 65.19  ? 365  ASP A CA  1 
ATOM 2762 C C   . ASP A 1 365  ? 164.926 122.638 183.093 1.00 65.56  ? 365  ASP A C   1 
ATOM 2763 O O   . ASP A 1 365  ? 163.907 123.331 183.141 1.00 64.66  ? 365  ASP A O   1 
ATOM 2764 C CB  . ASP A 1 365  ? 164.688 120.147 183.182 1.00 65.94  ? 365  ASP A CB  1 
ATOM 2765 C CG  . ASP A 1 365  ? 163.245 120.070 183.653 1.00 66.46  ? 365  ASP A CG  1 
ATOM 2766 O OD1 . ASP A 1 365  ? 162.988 119.434 184.698 1.00 65.10  ? 365  ASP A OD1 1 
ATOM 2767 O OD2 . ASP A 1 365  ? 162.367 120.645 182.980 1.00 66.62  ? 365  ASP A OD2 1 
ATOM 2768 N N   . LYS A 1 366  ? 166.039 122.961 183.751 1.00 60.21  ? 366  LYS A N   1 
ATOM 2769 C CA  . LYS A 1 366  ? 166.120 124.203 184.514 1.00 57.09  ? 366  LYS A CA  1 
ATOM 2770 C C   . LYS A 1 366  ? 166.010 125.418 183.599 1.00 55.67  ? 366  LYS A C   1 
ATOM 2771 O O   . LYS A 1 366  ? 165.351 126.410 183.941 1.00 57.53  ? 366  LYS A O   1 
ATOM 2772 C CB  . LYS A 1 366  ? 167.424 124.234 185.310 1.00 56.51  ? 366  LYS A CB  1 
ATOM 2773 C CG  . LYS A 1 366  ? 167.590 125.443 186.210 1.00 57.43  ? 366  LYS A CG  1 
ATOM 2774 C CD  . LYS A 1 366  ? 168.728 125.226 187.195 1.00 58.34  ? 366  LYS A CD  1 
ATOM 2775 C CE  . LYS A 1 366  ? 169.607 126.460 187.312 1.00 58.02  ? 366  LYS A CE  1 
ATOM 2776 N NZ  . LYS A 1 366  ? 168.928 127.549 188.063 1.00 57.49  ? 366  LYS A NZ  1 
ATOM 2777 N N   . PHE A 1 367  ? 166.651 125.361 182.428 1.00 51.26  ? 367  PHE A N   1 
ATOM 2778 C CA  . PHE A 1 367  ? 166.518 126.461 181.472 1.00 48.47  ? 367  PHE A CA  1 
ATOM 2779 C C   . PHE A 1 367  ? 165.075 126.607 180.988 1.00 50.72  ? 367  PHE A C   1 
ATOM 2780 O O   . PHE A 1 367  ? 164.561 127.728 180.866 1.00 55.73  ? 367  PHE A O   1 
ATOM 2781 C CB  . PHE A 1 367  ? 167.477 126.247 180.300 1.00 49.97  ? 367  PHE A CB  1 
ATOM 2782 C CG  . PHE A 1 367  ? 167.367 127.287 179.220 1.00 50.50  ? 367  PHE A CG  1 
ATOM 2783 C CD1 . PHE A 1 367  ? 168.154 128.426 179.260 1.00 50.40  ? 367  PHE A CD1 1 
ATOM 2784 C CD2 . PHE A 1 367  ? 166.512 127.109 178.146 1.00 52.58  ? 367  PHE A CD2 1 
ATOM 2785 C CE1 . PHE A 1 367  ? 168.068 129.380 178.267 1.00 49.23  ? 367  PHE A CE1 1 
ATOM 2786 C CE2 . PHE A 1 367  ? 166.423 128.060 177.150 1.00 52.17  ? 367  PHE A CE2 1 
ATOM 2787 C CZ  . PHE A 1 367  ? 167.203 129.196 177.210 1.00 49.07  ? 367  PHE A CZ  1 
ATOM 2788 N N   . ILE A 1 368  ? 164.406 125.485 180.711 1.00 54.72  ? 368  ILE A N   1 
ATOM 2789 C CA  . ILE A 1 368  ? 163.000 125.532 180.309 1.00 52.91  ? 368  ILE A CA  1 
ATOM 2790 C C   . ILE A 1 368  ? 162.133 126.067 181.442 1.00 51.51  ? 368  ILE A C   1 
ATOM 2791 O O   . ILE A 1 368  ? 161.138 126.756 181.202 1.00 52.92  ? 368  ILE A O   1 
ATOM 2792 C CB  . ILE A 1 368  ? 162.515 124.150 179.821 1.00 56.82  ? 368  ILE A CB  1 
ATOM 2793 C CG1 . ILE A 1 368  ? 163.595 123.443 179.011 1.00 55.32  ? 368  ILE A CG1 1 
ATOM 2794 C CG2 . ILE A 1 368  ? 161.243 124.266 179.006 1.00 55.96  ? 368  ILE A CG2 1 
ATOM 2795 C CD1 . ILE A 1 368  ? 163.893 124.084 177.680 1.00 54.36  ? 368  ILE A CD1 1 
ATOM 2796 N N   . GLN A 1 369  ? 162.485 125.757 182.690 1.00 48.81  ? 369  GLN A N   1 
ATOM 2797 C CA  . GLN A 1 369  ? 161.741 126.307 183.821 1.00 50.66  ? 369  GLN A CA  1 
ATOM 2798 C C   . GLN A 1 369  ? 161.905 127.821 183.913 1.00 51.15  ? 369  GLN A C   1 
ATOM 2799 O O   . GLN A 1 369  ? 160.940 128.539 184.204 1.00 52.96  ? 369  GLN A O   1 
ATOM 2800 C CB  . GLN A 1 369  ? 162.182 125.636 185.123 1.00 50.93  ? 369  GLN A CB  1 
ATOM 2801 C CG  . GLN A 1 369  ? 161.714 124.192 185.284 1.00 53.46  ? 369  GLN A CG  1 
ATOM 2802 C CD  . GLN A 1 369  ? 160.209 124.021 185.135 1.00 55.27  ? 369  GLN A CD  1 
ATOM 2803 O OE1 . GLN A 1 369  ? 159.439 124.926 185.456 1.00 54.57  ? 369  GLN A OE1 1 
ATOM 2804 N NE2 . GLN A 1 369  ? 159.785 122.871 184.620 1.00 51.91  ? 369  GLN A NE2 1 
ATOM 2805 N N   . GLN A 1 370  ? 163.120 128.322 183.682 1.00 46.83  ? 370  GLN A N   1 
ATOM 2806 C CA  . GLN A 1 370  ? 163.325 129.770 183.647 1.00 46.74  ? 370  GLN A CA  1 
ATOM 2807 C C   . GLN A 1 370  ? 162.495 130.409 182.539 1.00 45.02  ? 370  GLN A C   1 
ATOM 2808 O O   . GLN A 1 370  ? 161.822 131.432 182.749 1.00 43.43  ? 370  GLN A O   1 
ATOM 2809 C CB  . GLN A 1 370  ? 164.809 130.083 183.452 1.00 43.50  ? 370  GLN A CB  1 
ATOM 2810 C CG  . GLN A 1 370  ? 165.699 129.619 184.587 1.00 45.55  ? 370  GLN A CG  1 
ATOM 2811 C CD  . GLN A 1 370  ? 165.424 130.360 185.877 1.00 46.35  ? 370  GLN A CD  1 
ATOM 2812 O OE1 . GLN A 1 370  ? 165.172 131.564 185.872 1.00 42.55  ? 370  GLN A OE1 1 
ATOM 2813 N NE2 . GLN A 1 370  ? 165.471 129.642 186.993 1.00 50.08  ? 370  GLN A NE2 1 
ATOM 2814 N N   . LEU A 1 371  ? 162.524 129.803 181.350 1.00 39.64  ? 371  LEU A N   1 
ATOM 2815 C CA  . LEU A 1 371  ? 161.714 130.302 180.252 1.00 37.89  ? 371  LEU A CA  1 
ATOM 2816 C C   . LEU A 1 371  ? 160.241 130.302 180.643 1.00 39.20  ? 371  LEU A C   1 
ATOM 2817 O O   . LEU A 1 371  ? 159.490 131.205 180.261 1.00 38.83  ? 371  LEU A O   1 
ATOM 2818 C CB  . LEU A 1 371  ? 161.970 129.468 178.994 1.00 41.41  ? 371  LEU A CB  1 
ATOM 2819 C CG  . LEU A 1 371  ? 163.119 129.848 178.075 1.00 37.07  ? 371  LEU A CG  1 
ATOM 2820 C CD1 . LEU A 1 371  ? 163.067 128.999 176.820 1.00 39.86  ? 371  LEU A CD1 1 
ATOM 2821 C CD2 . LEU A 1 371  ? 163.071 131.324 177.731 1.00 38.32  ? 371  LEU A CD2 1 
ATOM 2822 N N   . GLY A 1 372  ? 159.808 129.260 181.372 1.00 38.25  ? 372  GLY A N   1 
ATOM 2823 C CA  . GLY A 1 372  ? 158.417 129.139 181.818 1.00 37.65  ? 372  GLY A CA  1 
ATOM 2824 C C   . GLY A 1 372  ? 157.976 130.209 182.714 1.00 37.56  ? 372  GLY A C   1 
ATOM 2825 O O   . GLY A 1 372  ? 156.860 130.727 182.593 1.00 38.72  ? 372  GLY A O   1 
ATOM 2826 N N   . ILE A 1 373  ? 158.825 130.495 183.659 1.00 37.88  ? 373  ILE A N   1 
ATOM 2827 C CA  . ILE A 1 373  ? 158.562 131.572 184.569 1.00 35.83  ? 373  ILE A CA  1 
ATOM 2828 C C   . ILE A 1 373  ? 158.422 132.875 183.797 1.00 30.83  ? 373  ILE A C   1 
ATOM 2829 O O   . ILE A 1 373  ? 157.494 133.662 184.030 1.00 31.97  ? 373  ILE A O   1 
ATOM 2830 C CB  . ILE A 1 373  ? 159.667 131.660 185.634 1.00 37.31  ? 373  ILE A CB  1 
ATOM 2831 C CG1 . ILE A 1 373  ? 159.698 130.393 186.489 1.00 35.74  ? 373  ILE A CG1 1 
ATOM 2832 C CG2 . ILE A 1 373  ? 159.465 132.890 186.507 1.00 36.58  ? 373  ILE A CG2 1 
ATOM 2833 C CD1 . ILE A 1 373  ? 160.912 130.297 187.384 1.00 35.94  ? 373  ILE A CD1 1 
ATOM 2834 N N   . SER A 1 374  ? 159.333 133.113 182.849 1.00 29.99  ? 374  SER A N   1 
ATOM 2835 C CA  . SER A 1 374  ? 159.283 134.354 182.081 1.00 26.37  ? 374  SER A CA  1 
ATOM 2836 C C   . SER A 1 374  ? 158.010 134.451 181.243 1.00 26.99  ? 374  SER A C   1 
ATOM 2837 O O   . SER A 1 374  ? 157.404 135.525 181.147 1.00 29.21  ? 374  SER A O   1 
ATOM 2838 C CB  . SER A 1 374  ? 160.522 134.469 181.199 1.00 30.45  ? 374  SER A CB  1 
ATOM 2839 O OG  . SER A 1 374  ? 161.699 134.563 181.982 1.00 30.90  ? 374  SER A OG  1 
ATOM 2840 N N   . VAL A 1 375  ? 157.592 133.345 180.622 1.00 34.42  ? 375  VAL A N   1 
ATOM 2841 C CA  . VAL A 1 375  ? 156.390 133.367 179.790 1.00 32.50  ? 375  VAL A CA  1 
ATOM 2842 C C   . VAL A 1 375  ? 155.140 133.522 180.649 1.00 33.58  ? 375  VAL A C   1 
ATOM 2843 O O   . VAL A 1 375  ? 154.226 134.283 180.309 1.00 34.38  ? 375  VAL A O   1 
ATOM 2844 C CB  . VAL A 1 375  ? 156.314 132.109 178.905 1.00 34.53  ? 375  VAL A CB  1 
ATOM 2845 C CG1 . VAL A 1 375  ? 155.092 132.173 178.010 1.00 35.19  ? 375  VAL A CG1 1 
ATOM 2846 C CG2 . VAL A 1 375  ? 157.548 132.006 178.047 1.00 34.93  ? 375  VAL A CG2 1 
ATOM 2847 N N   . ALA A 1 376  ? 155.074 132.800 181.772 1.00 33.13  ? 376  ALA A N   1 
ATOM 2848 C CA  . ALA A 1 376  ? 153.922 132.914 182.659 1.00 28.60  ? 376  ALA A CA  1 
ATOM 2849 C C   . ALA A 1 376  ? 153.800 134.316 183.235 1.00 33.26  ? 376  ALA A C   1 
ATOM 2850 O O   . ALA A 1 376  ? 152.685 134.793 183.473 1.00 36.24  ? 376  ALA A O   1 
ATOM 2851 C CB  . ALA A 1 376  ? 154.019 131.883 183.783 1.00 28.40  ? 376  ALA A CB  1 
ATOM 2852 N N   . ALA A 1 377  ? 154.928 134.991 183.461 1.00 28.62  ? 377  ALA A N   1 
ATOM 2853 C CA  . ALA A 1 377  ? 154.881 136.384 183.884 1.00 23.08  ? 377  ALA A CA  1 
ATOM 2854 C C   . ALA A 1 377  ? 154.433 137.321 182.770 1.00 27.26  ? 377  ALA A C   1 
ATOM 2855 O O   . ALA A 1 377  ? 154.212 138.505 183.038 1.00 33.58  ? 377  ALA A O   1 
ATOM 2856 C CB  . ALA A 1 377  ? 156.248 136.819 184.409 1.00 24.94  ? 377  ALA A CB  1 
ATOM 2857 N N   . GLN A 1 378  ? 154.306 136.824 181.536 1.00 26.32  ? 378  GLN A N   1 
ATOM 2858 C CA  . GLN A 1 378  ? 153.939 137.636 180.374 1.00 24.51  ? 378  GLN A CA  1 
ATOM 2859 C C   . GLN A 1 378  ? 154.934 138.768 180.142 1.00 25.99  ? 378  GLN A C   1 
ATOM 2860 O O   . GLN A 1 378  ? 154.566 139.852 179.684 1.00 24.62  ? 378  GLN A O   1 
ATOM 2861 C CB  . GLN A 1 378  ? 152.519 138.193 180.501 1.00 27.06  ? 378  GLN A CB  1 
ATOM 2862 C CG  . GLN A 1 378  ? 151.431 137.138 180.475 1.00 30.14  ? 378  GLN A CG  1 
ATOM 2863 C CD  . GLN A 1 378  ? 150.043 137.741 180.535 1.00 34.39  ? 378  GLN A CD  1 
ATOM 2864 O OE1 . GLN A 1 378  ? 149.762 138.600 181.371 1.00 34.46  ? 378  GLN A OE1 1 
ATOM 2865 N NE2 . GLN A 1 378  ? 149.166 137.294 179.645 1.00 33.45  ? 378  GLN A NE2 1 
ATOM 2866 N N   . MET A 1 379  ? 156.198 138.519 180.451 1.00 26.75  ? 379  MET A N   1 
ATOM 2867 C CA  . MET A 1 379  ? 157.252 139.512 180.339 1.00 20.67  ? 379  MET A CA  1 
ATOM 2868 C C   . MET A 1 379  ? 158.159 139.197 179.157 1.00 21.32  ? 379  MET A C   1 
ATOM 2869 O O   . MET A 1 379  ? 158.384 138.020 178.851 1.00 20.15  ? 379  MET A O   1 
ATOM 2870 C CB  . MET A 1 379  ? 158.086 139.549 181.626 1.00 18.09  ? 379  MET A CB  1 
ATOM 2871 C CG  . MET A 1 379  ? 157.314 139.968 182.873 1.00 18.60  ? 379  MET A CG  1 
ATOM 2872 S SD  . MET A 1 379  ? 156.991 141.739 182.990 1.00 32.02  ? 379  MET A SD  1 
ATOM 2873 C CE  . MET A 1 379  ? 155.338 141.842 182.315 1.00 19.13  ? 379  MET A CE  1 
ATOM 2874 N N   . PRO A 1 380  ? 158.711 140.213 178.478 1.00 14.29  ? 380  PRO A N   1 
ATOM 2875 C CA  . PRO A 1 380  ? 159.577 139.942 177.338 1.00 8.69   ? 380  PRO A CA  1 
ATOM 2876 C C   . PRO A 1 380  ? 161.049 139.821 177.696 1.00 14.47  ? 380  PRO A C   1 
ATOM 2877 O O   . PRO A 1 380  ? 161.892 139.825 176.793 1.00 21.34  ? 380  PRO A O   1 
ATOM 2878 C CB  . PRO A 1 380  ? 159.321 141.165 176.447 1.00 11.89  ? 380  PRO A CB  1 
ATOM 2879 C CG  . PRO A 1 380  ? 158.905 142.292 177.463 1.00 10.74  ? 380  PRO A CG  1 
ATOM 2880 C CD  . PRO A 1 380  ? 158.875 141.624 178.833 1.00 9.46   ? 380  PRO A CD  1 
ATOM 2881 N N   . ALA A 1 381  ? 161.387 139.718 178.980 1.00 13.94  ? 381  ALA A N   1 
ATOM 2882 C CA  . ALA A 1 381  ? 162.767 139.621 179.429 1.00 10.20  ? 381  ALA A CA  1 
ATOM 2883 C C   . ALA A 1 381  ? 162.937 138.398 180.317 1.00 12.46  ? 381  ALA A C   1 
ATOM 2884 O O   . ALA A 1 381  ? 162.064 138.079 181.129 1.00 14.94  ? 381  ALA A O   1 
ATOM 2885 C CB  . ALA A 1 381  ? 163.192 140.880 180.188 1.00 7.60   ? 381  ALA A CB  1 
ATOM 2886 N N   . GLY A 1 382  ? 164.065 137.716 180.151 1.00 14.20  ? 382  GLY A N   1 
ATOM 2887 C CA  . GLY A 1 382  ? 164.409 136.589 180.992 1.00 8.61   ? 382  GLY A CA  1 
ATOM 2888 C C   . GLY A 1 382  ? 165.865 136.641 181.396 1.00 14.15  ? 382  GLY A C   1 
ATOM 2889 O O   . GLY A 1 382  ? 166.565 137.603 181.069 1.00 23.38  ? 382  GLY A O   1 
ATOM 2890 N N   . SER A 1 383  ? 166.339 135.623 182.108 1.00 18.21  ? 383  SER A N   1 
ATOM 2891 C CA  . SER A 1 383  ? 167.732 135.581 182.521 1.00 22.52  ? 383  SER A CA  1 
ATOM 2892 C C   . SER A 1 383  ? 168.181 134.134 182.624 1.00 25.89  ? 383  SER A C   1 
ATOM 2893 O O   . SER A 1 383  ? 167.379 133.236 182.891 1.00 32.45  ? 383  SER A O   1 
ATOM 2894 C CB  . SER A 1 383  ? 167.952 136.291 183.861 1.00 26.74  ? 383  SER A CB  1 
ATOM 2895 O OG  . SER A 1 383  ? 169.309 136.213 184.263 1.00 34.08  ? 383  SER A OG  1 
ATOM 2896 N N   . TRP A 1 384  ? 169.477 133.920 182.409 1.00 35.58  ? 384  TRP A N   1 
ATOM 2897 C CA  . TRP A 1 384  ? 170.060 132.590 182.558 1.00 38.09  ? 384  TRP A CA  1 
ATOM 2898 C C   . TRP A 1 384  ? 171.557 132.754 182.783 1.00 43.26  ? 384  TRP A C   1 
ATOM 2899 O O   . TRP A 1 384  ? 172.273 133.178 181.870 1.00 46.84  ? 384  TRP A O   1 
ATOM 2900 C CB  . TRP A 1 384  ? 169.780 131.729 181.335 1.00 41.58  ? 384  TRP A CB  1 
ATOM 2901 C CG  . TRP A 1 384  ? 170.414 130.381 181.423 1.00 45.01  ? 384  TRP A CG  1 
ATOM 2902 C CD1 . TRP A 1 384  ? 171.497 129.936 180.725 1.00 44.03  ? 384  TRP A CD1 1 
ATOM 2903 C CD2 . TRP A 1 384  ? 170.013 129.303 182.273 1.00 42.73  ? 384  TRP A CD2 1 
ATOM 2904 N NE1 . TRP A 1 384  ? 171.791 128.644 181.083 1.00 41.96  ? 384  TRP A NE1 1 
ATOM 2905 C CE2 . TRP A 1 384  ? 170.894 128.232 182.033 1.00 42.82  ? 384  TRP A CE2 1 
ATOM 2906 C CE3 . TRP A 1 384  ? 168.991 129.139 183.212 1.00 43.66  ? 384  TRP A CE3 1 
ATOM 2907 C CZ2 . TRP A 1 384  ? 170.784 127.014 182.697 1.00 47.41  ? 384  TRP A CZ2 1 
ATOM 2908 C CZ3 . TRP A 1 384  ? 168.884 127.930 183.870 1.00 46.54  ? 384  TRP A CZ3 1 
ATOM 2909 C CH2 . TRP A 1 384  ? 169.774 126.883 183.610 1.00 47.04  ? 384  TRP A CH2 1 
ATOM 2910 N N   . GLN A 1 385  ? 172.018 132.415 183.988 1.00 42.46  ? 385  GLN A N   1 
ATOM 2911 C CA  . GLN A 1 385  ? 173.440 132.423 184.334 1.00 43.35  ? 385  GLN A CA  1 
ATOM 2912 C C   . GLN A 1 385  ? 174.076 133.790 184.076 1.00 42.21  ? 385  GLN A C   1 
ATOM 2913 O O   . GLN A 1 385  ? 175.167 133.899 183.513 1.00 42.60  ? 385  GLN A O   1 
ATOM 2914 C CB  . GLN A 1 385  ? 174.190 131.320 183.583 1.00 44.97  ? 385  GLN A CB  1 
ATOM 2915 C CG  . GLN A 1 385  ? 173.746 129.913 183.944 1.00 45.91  ? 385  GLN A CG  1 
ATOM 2916 C CD  . GLN A 1 385  ? 174.072 129.547 185.378 1.00 48.91  ? 385  GLN A CD  1 
ATOM 2917 O OE1 . GLN A 1 385  ? 175.129 129.904 185.897 1.00 47.74  ? 385  GLN A OE1 1 
ATOM 2918 N NE2 . GLN A 1 385  ? 173.161 128.831 186.026 1.00 48.88  ? 385  GLN A NE2 1 
ATOM 2919 N N   . GLY A 1 386  ? 173.379 134.842 184.497 1.00 35.51  ? 386  GLY A N   1 
ATOM 2920 C CA  . GLY A 1 386  ? 173.904 136.187 184.380 1.00 34.74  ? 386  GLY A CA  1 
ATOM 2921 C C   . GLY A 1 386  ? 173.751 136.829 183.023 1.00 35.31  ? 386  GLY A C   1 
ATOM 2922 O O   . GLY A 1 386  ? 174.255 137.939 182.821 1.00 37.75  ? 386  GLY A O   1 
ATOM 2923 N N   . TYR A 1 387  ? 173.075 136.172 182.085 1.00 34.31  ? 387  TYR A N   1 
ATOM 2924 C CA  . TYR A 1 387  ? 172.835 136.711 180.753 1.00 34.92  ? 387  TYR A CA  1 
ATOM 2925 C C   . TYR A 1 387  ? 171.349 136.992 180.602 1.00 33.45  ? 387  TYR A C   1 
ATOM 2926 O O   . TYR A 1 387  ? 170.517 136.124 180.887 1.00 30.45  ? 387  TYR A O   1 
ATOM 2927 C CB  . TYR A 1 387  ? 173.312 135.742 179.672 1.00 31.71  ? 387  TYR A CB  1 
ATOM 2928 C CG  . TYR A 1 387  ? 174.799 135.493 179.690 1.00 33.19  ? 387  TYR A CG  1 
ATOM 2929 C CD1 . TYR A 1 387  ? 175.304 134.202 179.714 1.00 33.18  ? 387  TYR A CD1 1 
ATOM 2930 C CD2 . TYR A 1 387  ? 175.699 136.549 179.678 1.00 35.63  ? 387  TYR A CD2 1 
ATOM 2931 C CE1 . TYR A 1 387  ? 176.662 133.970 179.732 1.00 34.82  ? 387  TYR A CE1 1 
ATOM 2932 C CE2 . TYR A 1 387  ? 177.060 136.327 179.694 1.00 37.31  ? 387  TYR A CE2 1 
ATOM 2933 C CZ  . TYR A 1 387  ? 177.537 135.034 179.720 1.00 39.47  ? 387  TYR A CZ  1 
ATOM 2934 O OH  . TYR A 1 387  ? 178.892 134.804 179.736 1.00 38.56  ? 387  TYR A OH  1 
ATOM 2935 N N   . GLU A 1 388  ? 171.020 138.202 180.166 1.00 26.37  ? 388  GLU A N   1 
ATOM 2936 C CA  . GLU A 1 388  ? 169.631 138.555 179.925 1.00 19.88  ? 388  GLU A CA  1 
ATOM 2937 C C   . GLU A 1 388  ? 169.145 137.921 178.630 1.00 21.98  ? 388  GLU A C   1 
ATOM 2938 O O   . GLU A 1 388  ? 169.917 137.697 177.695 1.00 32.17  ? 388  GLU A O   1 
ATOM 2939 C CB  . GLU A 1 388  ? 169.470 140.073 179.862 1.00 23.27  ? 388  GLU A CB  1 
ATOM 2940 C CG  . GLU A 1 388  ? 169.571 140.743 181.213 1.00 21.24  ? 388  GLU A CG  1 
ATOM 2941 C CD  . GLU A 1 388  ? 170.980 140.716 181.762 1.00 27.72  ? 388  GLU A CD  1 
ATOM 2942 O OE1 . GLU A 1 388  ? 171.226 139.974 182.735 1.00 29.60  ? 388  GLU A OE1 1 
ATOM 2943 O OE2 . GLU A 1 388  ? 171.843 141.439 181.225 1.00 31.36  ? 388  GLU A OE2 1 
ATOM 2944 N N   . LEU A 1 389  ? 167.850 137.629 178.582 1.00 11.92  ? 389  LEU A N   1 
ATOM 2945 C CA  . LEU A 1 389  ? 167.231 137.005 177.423 1.00 13.49  ? 389  LEU A CA  1 
ATOM 2946 C C   . LEU A 1 389  ? 166.157 137.915 176.850 1.00 13.15  ? 389  LEU A C   1 
ATOM 2947 O O   . LEU A 1 389  ? 165.438 138.595 177.590 1.00 16.15  ? 389  LEU A O   1 
ATOM 2948 C CB  . LEU A 1 389  ? 166.620 135.639 177.773 1.00 16.10  ? 389  LEU A CB  1 
ATOM 2949 C CG  . LEU A 1 389  ? 167.565 134.492 178.143 1.00 11.83  ? 389  LEU A CG  1 
ATOM 2950 C CD1 . LEU A 1 389  ? 166.871 133.144 178.055 1.00 16.86  ? 389  LEU A CD1 1 
ATOM 2951 C CD2 . LEU A 1 389  ? 168.777 134.515 177.240 1.00 15.10  ? 389  LEU A CD2 1 
ATOM 2952 N N   . GLU A 1 390  ? 166.059 137.919 175.526 1.00 18.01  ? 390  GLU A N   1 
ATOM 2953 C CA  . GLU A 1 390  ? 165.062 138.692 174.798 1.00 15.09  ? 390  GLU A CA  1 
ATOM 2954 C C   . GLU A 1 390  ? 163.964 137.728 174.364 1.00 20.28  ? 390  GLU A C   1 
ATOM 2955 O O   . GLU A 1 390  ? 164.164 136.922 173.450 1.00 33.28  ? 390  GLU A O   1 
ATOM 2956 C CB  . GLU A 1 390  ? 165.705 139.389 173.601 1.00 17.62  ? 390  GLU A CB  1 
ATOM 2957 C CG  . GLU A 1 390  ? 164.728 139.952 172.594 1.00 21.49  ? 390  GLU A CG  1 
ATOM 2958 C CD  . GLU A 1 390  ? 164.040 141.199 173.099 1.00 28.14  ? 390  GLU A CD  1 
ATOM 2959 O OE1 . GLU A 1 390  ? 162.799 141.268 173.020 1.00 29.92  ? 390  GLU A OE1 1 
ATOM 2960 O OE2 . GLU A 1 390  ? 164.742 142.114 173.579 1.00 26.55  ? 390  GLU A OE2 1 
ATOM 2961 N N   . LEU A 1 391  ? 162.810 137.799 175.028 1.00 15.59  ? 391  LEU A N   1 
ATOM 2962 C CA  . LEU A 1 391  ? 161.731 136.844 174.806 1.00 20.98  ? 391  LEU A CA  1 
ATOM 2963 C C   . LEU A 1 391  ? 160.496 137.482 174.182 1.00 23.24  ? 391  LEU A C   1 
ATOM 2964 O O   . LEU A 1 391  ? 159.410 136.895 174.229 1.00 18.47  ? 391  LEU A O   1 
ATOM 2965 C CB  . LEU A 1 391  ? 161.362 136.148 176.115 1.00 21.72  ? 391  LEU A CB  1 
ATOM 2966 C CG  . LEU A 1 391  ? 162.524 135.604 176.943 1.00 15.32  ? 391  LEU A CG  1 
ATOM 2967 C CD1 . LEU A 1 391  ? 161.988 134.787 178.083 1.00 9.83   ? 391  LEU A CD1 1 
ATOM 2968 C CD2 . LEU A 1 391  ? 163.445 134.758 176.085 1.00 18.90  ? 391  LEU A CD2 1 
ATOM 2969 N N   . SER A 1 392  ? 160.633 138.676 173.607 1.00 24.60  ? 392  SER A N   1 
ATOM 2970 C CA  . SER A 1 392  ? 159.510 139.275 172.894 1.00 23.93  ? 392  SER A CA  1 
ATOM 2971 C C   . SER A 1 392  ? 159.204 138.511 171.611 1.00 29.06  ? 392  SER A C   1 
ATOM 2972 O O   . SER A 1 392  ? 158.034 138.340 171.249 1.00 28.27  ? 392  SER A O   1 
ATOM 2973 C CB  . SER A 1 392  ? 159.800 140.743 172.597 1.00 21.87  ? 392  SER A CB  1 
ATOM 2974 O OG  . SER A 1 392  ? 160.879 140.877 171.691 1.00 24.19  ? 392  SER A OG  1 
ATOM 2975 N N   . GLN A 1 393  ? 160.238 138.047 170.911 1.00 25.55  ? 393  GLN A N   1 
ATOM 2976 C CA  . GLN A 1 393  ? 160.053 137.214 169.729 1.00 27.09  ? 393  GLN A CA  1 
ATOM 2977 C C   . GLN A 1 393  ? 159.816 135.751 170.074 1.00 34.14  ? 393  GLN A C   1 
ATOM 2978 O O   . GLN A 1 393  ? 159.513 134.961 169.174 1.00 39.08  ? 393  GLN A O   1 
ATOM 2979 C CB  . GLN A 1 393  ? 161.264 137.326 168.796 1.00 30.47  ? 393  GLN A CB  1 
ATOM 2980 C CG  . GLN A 1 393  ? 161.378 138.645 168.047 1.00 29.96  ? 393  GLN A CG  1 
ATOM 2981 C CD  . GLN A 1 393  ? 161.721 139.807 168.953 1.00 31.51  ? 393  GLN A CD  1 
ATOM 2982 O OE1 . GLN A 1 393  ? 160.965 140.768 169.061 1.00 33.33  ? 393  GLN A OE1 1 
ATOM 2983 N NE2 . GLN A 1 393  ? 162.865 139.720 169.617 1.00 32.16  ? 393  GLN A NE2 1 
ATOM 2984 N N   . PHE A 1 394  ? 159.949 135.374 171.343 1.00 40.34  ? 394  PHE A N   1 
ATOM 2985 C CA  . PHE A 1 394  ? 159.705 134.002 171.779 1.00 40.31  ? 394  PHE A CA  1 
ATOM 2986 C C   . PHE A 1 394  ? 158.201 133.766 171.800 1.00 38.13  ? 394  PHE A C   1 
ATOM 2987 O O   . PHE A 1 394  ? 157.515 134.115 172.764 1.00 41.79  ? 394  PHE A O   1 
ATOM 2988 C CB  . PHE A 1 394  ? 160.331 133.754 173.146 1.00 39.79  ? 394  PHE A CB  1 
ATOM 2989 C CG  . PHE A 1 394  ? 160.429 132.304 173.513 1.00 37.99  ? 394  PHE A CG  1 
ATOM 2990 C CD1 . PHE A 1 394  ? 161.304 131.465 172.846 1.00 39.96  ? 394  PHE A CD1 1 
ATOM 2991 C CD2 . PHE A 1 394  ? 159.655 131.780 174.531 1.00 38.19  ? 394  PHE A CD2 1 
ATOM 2992 C CE1 . PHE A 1 394  ? 161.393 130.130 173.181 1.00 40.62  ? 394  PHE A CE1 1 
ATOM 2993 C CE2 . PHE A 1 394  ? 159.748 130.454 174.865 1.00 40.00  ? 394  PHE A CE2 1 
ATOM 2994 C CZ  . PHE A 1 394  ? 160.616 129.624 174.197 1.00 42.69  ? 394  PHE A CZ  1 
ATOM 2995 N N   . THR A 1 395  ? 157.685 133.173 170.728 1.00 48.58  ? 395  THR A N   1 
ATOM 2996 C CA  . THR A 1 395  ? 156.261 132.927 170.589 1.00 52.60  ? 395  THR A CA  1 
ATOM 2997 C C   . THR A 1 395  ? 155.856 131.690 171.386 1.00 52.31  ? 395  THR A C   1 
ATOM 2998 O O   . THR A 1 395  ? 156.687 130.985 171.964 1.00 51.65  ? 395  THR A O   1 
ATOM 2999 C CB  . THR A 1 395  ? 155.890 132.764 169.116 1.00 53.19  ? 395  THR A CB  1 
ATOM 3000 O OG1 . THR A 1 395  ? 156.586 131.637 168.569 1.00 50.20  ? 395  THR A OG1 1 
ATOM 3001 C CG2 . THR A 1 395  ? 156.268 134.010 168.332 1.00 51.21  ? 395  THR A CG2 1 
ATOM 3002 N N   . GLU A 1 396  ? 154.549 131.426 171.423 1.00 62.34  ? 396  GLU A N   1 
ATOM 3003 C CA  . GLU A 1 396  ? 154.059 130.209 172.057 1.00 63.14  ? 396  GLU A CA  1 
ATOM 3004 C C   . GLU A 1 396  ? 154.489 128.968 171.284 1.00 63.27  ? 396  GLU A C   1 
ATOM 3005 O O   . GLU A 1 396  ? 154.726 127.913 171.886 1.00 60.01  ? 396  GLU A O   1 
ATOM 3006 C CB  . GLU A 1 396  ? 152.535 130.266 172.185 1.00 61.55  ? 396  GLU A CB  1 
ATOM 3007 C CG  . GLU A 1 396  ? 151.913 129.065 172.875 1.00 61.69  ? 396  GLU A CG  1 
ATOM 3008 C CD  . GLU A 1 396  ? 152.324 128.945 174.330 1.00 64.12  ? 396  GLU A CD  1 
ATOM 3009 O OE1 . GLU A 1 396  ? 152.662 129.978 174.945 1.00 64.01  ? 396  GLU A OE1 1 
ATOM 3010 O OE2 . GLU A 1 396  ? 152.311 127.814 174.861 1.00 62.86  ? 396  GLU A OE2 1 
ATOM 3011 N N   . GLN A 1 397  ? 154.600 129.079 169.958 1.00 65.91  ? 397  GLN A N   1 
ATOM 3012 C CA  . GLN A 1 397  ? 155.030 127.945 169.147 1.00 64.84  ? 397  GLN A CA  1 
ATOM 3013 C C   . GLN A 1 397  ? 156.427 127.485 169.543 1.00 66.68  ? 397  GLN A C   1 
ATOM 3014 O O   . GLN A 1 397  ? 156.665 126.289 169.736 1.00 67.80  ? 397  GLN A O   1 
ATOM 3015 C CB  . GLN A 1 397  ? 154.990 128.314 167.665 1.00 65.66  ? 397  GLN A CB  1 
ATOM 3016 C CG  . GLN A 1 397  ? 155.338 127.165 166.734 1.00 65.90  ? 397  GLN A CG  1 
ATOM 3017 C CD  . GLN A 1 397  ? 155.235 127.547 165.272 1.00 68.54  ? 397  GLN A CD  1 
ATOM 3018 O OE1 . GLN A 1 397  ? 154.935 128.694 164.938 1.00 68.93  ? 397  GLN A OE1 1 
ATOM 3019 N NE2 . GLN A 1 397  ? 155.482 126.586 164.390 1.00 65.80  ? 397  GLN A NE2 1 
ATOM 3020 N N   . GLN A 1 398  ? 157.365 128.425 169.677 1.00 61.21  ? 398  GLN A N   1 
ATOM 3021 C CA  . GLN A 1 398  ? 158.716 128.061 170.090 1.00 58.73  ? 398  GLN A CA  1 
ATOM 3022 C C   . GLN A 1 398  ? 158.739 127.535 171.519 1.00 57.38  ? 398  GLN A C   1 
ATOM 3023 O O   . GLN A 1 398  ? 159.564 126.676 171.852 1.00 57.84  ? 398  GLN A O   1 
ATOM 3024 C CB  . GLN A 1 398  ? 159.650 129.261 169.942 1.00 58.80  ? 398  GLN A CB  1 
ATOM 3025 C CG  . GLN A 1 398  ? 159.484 130.012 168.632 1.00 57.34  ? 398  GLN A CG  1 
ATOM 3026 C CD  . GLN A 1 398  ? 160.699 130.844 168.280 1.00 58.61  ? 398  GLN A CD  1 
ATOM 3027 O OE1 . GLN A 1 398  ? 161.758 130.705 168.892 1.00 58.25  ? 398  GLN A OE1 1 
ATOM 3028 N NE2 . GLN A 1 398  ? 160.554 131.714 167.288 1.00 60.43  ? 398  GLN A NE2 1 
ATOM 3029 N N   . TRP A 1 399  ? 157.841 128.033 172.371 1.00 56.84  ? 399  TRP A N   1 
ATOM 3030 C CA  . TRP A 1 399  ? 157.706 127.490 173.719 1.00 57.01  ? 399  TRP A CA  1 
ATOM 3031 C C   . TRP A 1 399  ? 157.319 126.017 173.677 1.00 60.60  ? 399  TRP A C   1 
ATOM 3032 O O   . TRP A 1 399  ? 157.911 125.188 174.382 1.00 61.55  ? 399  TRP A O   1 
ATOM 3033 C CB  . TRP A 1 399  ? 156.667 128.307 174.495 1.00 57.98  ? 399  TRP A CB  1 
ATOM 3034 C CG  . TRP A 1 399  ? 156.467 127.900 175.928 1.00 58.51  ? 399  TRP A CG  1 
ATOM 3035 C CD1 . TRP A 1 399  ? 155.432 127.165 176.426 1.00 60.27  ? 399  TRP A CD1 1 
ATOM 3036 C CD2 . TRP A 1 399  ? 157.284 128.243 177.050 1.00 58.08  ? 399  TRP A CD2 1 
ATOM 3037 N NE1 . TRP A 1 399  ? 155.565 127.005 177.780 1.00 58.36  ? 399  TRP A NE1 1 
ATOM 3038 C CE2 . TRP A 1 399  ? 156.689 127.658 178.189 1.00 57.30  ? 399  TRP A CE2 1 
ATOM 3039 C CE3 . TRP A 1 399  ? 158.467 128.971 177.206 1.00 59.21  ? 399  TRP A CE3 1 
ATOM 3040 C CZ2 . TRP A 1 399  ? 157.222 127.777 179.385 1.00 59.10  ? 399  TRP A CZ2 1 
ATOM 3041 C CZ3 . TRP A 1 399  ? 158.943 129.064 178.391 1.00 60.79  ? 399  TRP A CZ3 1 
ATOM 3042 C CH2 . TRP A 1 399  ? 158.365 128.434 179.398 1.00 60.93  ? 399  TRP A CH2 1 
ATOM 3043 N N   . HIS A 1 400  ? 156.334 125.668 172.845 1.00 69.17  ? 400  HIS A N   1 
ATOM 3044 C CA  . HIS A 1 400  ? 155.961 124.264 172.710 1.00 69.63  ? 400  HIS A CA  1 
ATOM 3045 C C   . HIS A 1 400  ? 157.062 123.446 172.052 1.00 66.64  ? 400  HIS A C   1 
ATOM 3046 O O   . HIS A 1 400  ? 157.219 122.268 172.374 1.00 68.45  ? 400  HIS A O   1 
ATOM 3047 C CB  . HIS A 1 400  ? 154.653 124.118 171.933 1.00 68.48  ? 400  HIS A CB  1 
ATOM 3048 C CG  . HIS A 1 400  ? 153.460 124.669 172.649 1.00 69.10  ? 400  HIS A CG  1 
ATOM 3049 N ND1 . HIS A 1 400  ? 152.877 124.028 173.720 1.00 69.92  ? 400  HIS A ND1 1 
ATOM 3050 C CD2 . HIS A 1 400  ? 152.727 125.786 172.435 1.00 69.55  ? 400  HIS A CD2 1 
ATOM 3051 C CE1 . HIS A 1 400  ? 151.844 124.735 174.145 1.00 70.05  ? 400  HIS A CE1 1 
ATOM 3052 N NE2 . HIS A 1 400  ? 151.731 125.806 173.381 1.00 70.16  ? 400  HIS A NE2 1 
ATOM 3053 N N   . ASP A 1 401  ? 157.829 124.037 171.133 1.00 67.74  ? 401  ASP A N   1 
ATOM 3054 C CA  . ASP A 1 401  ? 158.968 123.314 170.571 1.00 68.73  ? 401  ASP A CA  1 
ATOM 3055 C C   . ASP A 1 401  ? 159.993 122.984 171.649 1.00 69.37  ? 401  ASP A C   1 
ATOM 3056 O O   . ASP A 1 401  ? 160.517 121.866 171.694 1.00 70.34  ? 401  ASP A O   1 
ATOM 3057 C CB  . ASP A 1 401  ? 159.620 124.113 169.441 1.00 69.29  ? 401  ASP A CB  1 
ATOM 3058 C CG  . ASP A 1 401  ? 158.614 124.634 168.438 1.00 70.63  ? 401  ASP A CG  1 
ATOM 3059 O OD1 . ASP A 1 401  ? 157.513 124.051 168.341 1.00 69.33  ? 401  ASP A OD1 1 
ATOM 3060 O OD2 . ASP A 1 401  ? 158.923 125.625 167.743 1.00 71.49  ? 401  ASP A OD2 1 
ATOM 3061 N N   . CYS A 1 402  ? 160.286 123.941 172.534 1.00 69.35  ? 402  CYS A N   1 
ATOM 3062 C CA  . CYS A 1 402  ? 161.220 123.676 173.626 1.00 67.46  ? 402  CYS A CA  1 
ATOM 3063 C C   . CYS A 1 402  ? 160.683 122.603 174.568 1.00 66.92  ? 402  CYS A C   1 
ATOM 3064 O O   . CYS A 1 402  ? 161.415 121.685 174.964 1.00 67.54  ? 402  CYS A O   1 
ATOM 3065 C CB  . CYS A 1 402  ? 161.513 124.965 174.393 1.00 64.83  ? 402  CYS A CB  1 
ATOM 3066 S SG  . CYS A 1 402  ? 162.388 126.224 173.435 1.00 68.70  ? 402  CYS A SG  1 
ATOM 3067 N N   . GLN A 1 403  ? 159.401 122.698 174.934 1.00 67.71  ? 403  GLN A N   1 
ATOM 3068 C CA  . GLN A 1 403  ? 158.823 121.696 175.826 1.00 69.07  ? 403  GLN A CA  1 
ATOM 3069 C C   . GLN A 1 403  ? 158.817 120.313 175.182 1.00 70.73  ? 403  GLN A C   1 
ATOM 3070 O O   . GLN A 1 403  ? 159.127 119.315 175.843 1.00 70.48  ? 403  GLN A O   1 
ATOM 3071 C CB  . GLN A 1 403  ? 157.411 122.106 176.241 1.00 67.52  ? 403  GLN A CB  1 
ATOM 3072 C CG  . GLN A 1 403  ? 157.345 123.433 176.977 1.00 66.70  ? 403  GLN A CG  1 
ATOM 3073 C CD  . GLN A 1 403  ? 156.243 123.471 178.017 1.00 68.11  ? 403  GLN A CD  1 
ATOM 3074 O OE1 . GLN A 1 403  ? 156.455 123.114 179.176 1.00 67.59  ? 403  GLN A OE1 1 
ATOM 3075 N NE2 . GLN A 1 403  ? 155.058 123.905 177.607 1.00 69.81  ? 403  GLN A NE2 1 
ATOM 3076 N N   . ALA A 1 404  ? 158.473 120.234 173.895 1.00 76.40  ? 404  ALA A N   1 
ATOM 3077 C CA  . ALA A 1 404  ? 158.464 118.953 173.199 1.00 75.42  ? 404  ALA A CA  1 
ATOM 3078 C C   . ALA A 1 404  ? 159.871 118.389 173.066 1.00 75.58  ? 404  ALA A C   1 
ATOM 3079 O O   . ALA A 1 404  ? 160.064 117.172 173.141 1.00 78.99  ? 404  ALA A O   1 
ATOM 3080 C CB  . ALA A 1 404  ? 157.814 119.105 171.825 1.00 74.48  ? 404  ALA A CB  1 
ATOM 3081 N N   . LEU A 1 405  ? 160.864 119.256 172.861 1.00 75.95  ? 405  LEU A N   1 
ATOM 3082 C CA  . LEU A 1 405  ? 162.250 118.802 172.848 1.00 76.10  ? 405  LEU A CA  1 
ATOM 3083 C C   . LEU A 1 405  ? 162.621 118.202 174.197 1.00 75.22  ? 405  LEU A C   1 
ATOM 3084 O O   . LEU A 1 405  ? 163.271 117.152 174.268 1.00 76.83  ? 405  LEU A O   1 
ATOM 3085 C CB  . LEU A 1 405  ? 163.174 119.969 172.482 1.00 73.85  ? 405  LEU A CB  1 
ATOM 3086 C CG  . LEU A 1 405  ? 164.677 119.888 172.775 1.00 74.91  ? 405  LEU A CG  1 
ATOM 3087 C CD1 . LEU A 1 405  ? 165.251 118.602 172.223 1.00 76.21  ? 405  LEU A CD1 1 
ATOM 3088 C CD2 . LEU A 1 405  ? 165.439 121.086 172.218 1.00 75.71  ? 405  LEU A CD2 1 
ATOM 3089 N N   . LEU A 1 406  ? 162.192 118.851 175.282 1.00 74.72  ? 406  LEU A N   1 
ATOM 3090 C CA  . LEU A 1 406  ? 162.427 118.308 176.617 1.00 75.97  ? 406  LEU A CA  1 
ATOM 3091 C C   . LEU A 1 406  ? 161.797 116.927 176.775 1.00 77.12  ? 406  LEU A C   1 
ATOM 3092 O O   . LEU A 1 406  ? 162.458 115.976 177.212 1.00 78.73  ? 406  LEU A O   1 
ATOM 3093 C CB  . LEU A 1 406  ? 161.880 119.266 177.673 1.00 75.45  ? 406  LEU A CB  1 
ATOM 3094 C CG  . LEU A 1 406  ? 162.220 118.937 179.128 1.00 75.04  ? 406  LEU A CG  1 
ATOM 3095 C CD1 . LEU A 1 406  ? 163.722 118.977 179.363 1.00 73.71  ? 406  LEU A CD1 1 
ATOM 3096 C CD2 . LEU A 1 406  ? 161.492 119.881 180.068 1.00 75.16  ? 406  LEU A CD2 1 
ATOM 3097 N N   . THR A 1 407  ? 160.511 116.801 176.429 1.00 82.04  ? 407  THR A N   1 
ATOM 3098 C CA  . THR A 1 407  ? 159.824 115.522 176.608 1.00 82.84  ? 407  THR A CA  1 
ATOM 3099 C C   . THR A 1 407  ? 160.440 114.429 175.744 1.00 83.13  ? 407  THR A C   1 
ATOM 3100 O O   . THR A 1 407  ? 160.575 113.283 176.187 1.00 82.38  ? 407  THR A O   1 
ATOM 3101 C CB  . THR A 1 407  ? 158.328 115.650 176.305 1.00 80.87  ? 407  THR A CB  1 
ATOM 3102 O OG1 . THR A 1 407  ? 158.117 115.659 174.886 1.00 80.77  ? 407  THR A OG1 1 
ATOM 3103 C CG2 . THR A 1 407  ? 157.734 116.895 176.942 1.00 80.22  ? 407  THR A CG2 1 
ATOM 3104 N N   . ARG A 1 408  ? 160.804 114.756 174.503 1.00 85.29  ? 408  ARG A N   1 
ATOM 3105 C CA  . ARG A 1 408  ? 161.405 113.761 173.622 1.00 84.36  ? 408  ARG A CA  1 
ATOM 3106 C C   . ARG A 1 408  ? 162.777 113.330 174.135 1.00 83.62  ? 408  ARG A C   1 
ATOM 3107 O O   . ARG A 1 408  ? 163.102 112.134 174.129 1.00 85.96  ? 408  ARG A O   1 
ATOM 3108 C CB  . ARG A 1 408  ? 161.469 114.318 172.197 1.00 84.00  ? 408  ARG A CB  1 
ATOM 3109 C CG  . ARG A 1 408  ? 161.902 113.335 171.119 1.00 85.61  ? 408  ARG A CG  1 
ATOM 3110 C CD  . ARG A 1 408  ? 163.401 113.380 170.948 1.00 86.13  ? 408  ARG A CD  1 
ATOM 3111 N NE  . ARG A 1 408  ? 163.819 114.711 170.526 1.00 86.17  ? 408  ARG A NE  1 
ATOM 3112 C CZ  . ARG A 1 408  ? 165.062 115.162 170.591 1.00 85.86  ? 408  ARG A CZ  1 
ATOM 3113 N NH1 . ARG A 1 408  ? 166.032 114.435 171.113 1.00 85.14  ? 408  ARG A NH1 1 
ATOM 3114 N NH2 . ARG A 1 408  ? 165.336 116.374 170.124 1.00 85.81  ? 408  ARG A NH2 1 
ATOM 3115 N N   . TRP A 1 409  ? 163.585 114.280 174.615 1.00 82.44  ? 409  TRP A N   1 
ATOM 3116 C CA  . TRP A 1 409  ? 164.858 113.913 175.228 1.00 84.35  ? 409  TRP A CA  1 
ATOM 3117 C C   . TRP A 1 409  ? 164.642 112.978 176.411 1.00 85.21  ? 409  TRP A C   1 
ATOM 3118 O O   . TRP A 1 409  ? 165.299 111.933 176.514 1.00 86.60  ? 409  TRP A O   1 
ATOM 3119 C CB  . TRP A 1 409  ? 165.612 115.169 175.671 1.00 83.65  ? 409  TRP A CB  1 
ATOM 3120 C CG  . TRP A 1 409  ? 167.063 114.930 175.974 1.00 84.65  ? 409  TRP A CG  1 
ATOM 3121 C CD1 . TRP A 1 409  ? 167.697 113.726 176.039 1.00 86.35  ? 409  TRP A CD1 1 
ATOM 3122 C CD2 . TRP A 1 409  ? 168.053 115.920 176.287 1.00 85.26  ? 409  TRP A CD2 1 
ATOM 3123 N NE1 . TRP A 1 409  ? 169.017 113.903 176.358 1.00 86.20  ? 409  TRP A NE1 1 
ATOM 3124 C CE2 . TRP A 1 409  ? 169.264 115.241 176.514 1.00 85.44  ? 409  TRP A CE2 1 
ATOM 3125 C CE3 . TRP A 1 409  ? 168.034 117.312 176.391 1.00 83.46  ? 409  TRP A CE3 1 
ATOM 3126 C CZ2 . TRP A 1 409  ? 170.445 115.906 176.839 1.00 85.10  ? 409  TRP A CZ2 1 
ATOM 3127 C CZ3 . TRP A 1 409  ? 169.205 117.967 176.724 1.00 83.48  ? 409  TRP A CZ3 1 
ATOM 3128 C CH2 . TRP A 1 409  ? 170.395 117.267 176.932 1.00 83.77  ? 409  TRP A CH2 1 
ATOM 3129 N N   . GLN A 1 410  ? 163.706 113.323 177.301 1.00 83.94  ? 410  GLN A N   1 
ATOM 3130 C CA  . GLN A 1 410  ? 163.470 112.495 178.476 1.00 83.32  ? 410  GLN A CA  1 
ATOM 3131 C C   . GLN A 1 410  ? 162.987 111.112 178.090 1.00 85.62  ? 410  GLN A C   1 
ATOM 3132 O O   . GLN A 1 410  ? 163.518 110.134 178.589 1.00 85.62  ? 410  GLN A O   1 
ATOM 3133 C CB  . GLN A 1 410  ? 162.470 113.159 179.417 1.00 83.94  ? 410  GLN A CB  1 
ATOM 3134 C CG  . GLN A 1 410  ? 162.873 114.542 179.884 1.00 86.04  ? 410  GLN A CG  1 
ATOM 3135 C CD  . GLN A 1 410  ? 162.456 114.813 181.313 1.00 85.80  ? 410  GLN A CD  1 
ATOM 3136 O OE1 . GLN A 1 410  ? 163.061 114.302 182.254 1.00 84.38  ? 410  GLN A OE1 1 
ATOM 3137 N NE2 . GLN A 1 410  ? 161.411 115.613 181.483 1.00 84.67  ? 410  GLN A NE2 1 
ATOM 3138 N N   . GLN A 1 411  ? 162.029 110.999 177.170 1.00 89.84  ? 411  GLN A N   1 
ATOM 3139 C CA  . GLN A 1 411  ? 161.547 109.676 176.781 1.00 89.54  ? 411  GLN A CA  1 
ATOM 3140 C C   . GLN A 1 411  ? 162.637 108.872 176.088 1.00 89.05  ? 411  GLN A C   1 
ATOM 3141 O O   . GLN A 1 411  ? 162.600 107.637 176.109 1.00 89.23  ? 411  GLN A O   1 
ATOM 3142 C CB  . GLN A 1 411  ? 160.312 109.788 175.882 1.00 88.57  ? 411  GLN A CB  1 
ATOM 3143 C CG  . GLN A 1 411  ? 160.553 110.439 174.537 1.00 89.67  ? 411  GLN A CG  1 
ATOM 3144 C CD  . GLN A 1 411  ? 159.285 110.574 173.718 1.00 89.52  ? 411  GLN A CD  1 
ATOM 3145 O OE1 . GLN A 1 411  ? 158.215 110.131 174.133 1.00 89.25  ? 411  GLN A OE1 1 
ATOM 3146 N NE2 . GLN A 1 411  ? 159.399 111.186 172.545 1.00 88.95  ? 411  GLN A NE2 1 
ATOM 3147 N N   . GLU A 1 412  ? 163.614 109.545 175.473 1.00 90.17  ? 412  GLU A N   1 
ATOM 3148 C CA  . GLU A 1 412  ? 164.781 108.821 174.984 1.00 90.27  ? 412  GLU A CA  1 
ATOM 3149 C C   . GLU A 1 412  ? 165.673 108.356 176.130 1.00 90.21  ? 412  GLU A C   1 
ATOM 3150 O O   . GLU A 1 412  ? 166.310 107.301 176.025 1.00 90.10  ? 412  GLU A O   1 
ATOM 3151 C CB  . GLU A 1 412  ? 165.574 109.687 174.004 1.00 89.40  ? 412  GLU A CB  1 
ATOM 3152 C CG  . GLU A 1 412  ? 166.788 108.985 173.412 1.00 90.63  ? 412  GLU A CG  1 
ATOM 3153 C CD  . GLU A 1 412  ? 166.411 107.799 172.542 1.00 92.05  ? 412  GLU A CD  1 
ATOM 3154 O OE1 . GLU A 1 412  ? 165.288 107.789 171.996 1.00 93.13  ? 412  GLU A OE1 1 
ATOM 3155 O OE2 . GLU A 1 412  ? 167.236 106.870 172.411 1.00 90.70  ? 412  GLU A OE2 1 
ATOM 3156 N N   . ILE A 1 413  ? 165.734 109.120 177.225 1.00 90.40  ? 413  ILE A N   1 
ATOM 3157 C CA  . ILE A 1 413  ? 166.581 108.730 178.353 1.00 91.44  ? 413  ILE A CA  1 
ATOM 3158 C C   . ILE A 1 413  ? 166.103 107.415 178.960 1.00 90.73  ? 413  ILE A C   1 
ATOM 3159 O O   . ILE A 1 413  ? 166.903 106.505 179.212 1.00 90.48  ? 413  ILE A O   1 
ATOM 3160 C CB  . ILE A 1 413  ? 166.633 109.853 179.406 1.00 91.41  ? 413  ILE A CB  1 
ATOM 3161 C CG1 . ILE A 1 413  ? 167.204 111.134 178.796 1.00 91.00  ? 413  ILE A CG1 1 
ATOM 3162 C CG2 . ILE A 1 413  ? 167.459 109.419 180.608 1.00 89.89  ? 413  ILE A CG2 1 
ATOM 3163 C CD1 . ILE A 1 413  ? 168.615 110.989 178.277 1.00 89.69  ? 413  ILE A CD1 1 
ATOM 3164 N N   . GLU A 1 414  ? 164.802 107.289 179.203 1.00 89.09  ? 414  GLU A N   1 
ATOM 3165 C CA  . GLU A 1 414  ? 164.241 106.036 179.698 1.00 90.12  ? 414  GLU A CA  1 
ATOM 3166 C C   . GLU A 1 414  ? 164.255 104.966 178.609 1.00 89.35  ? 414  GLU A C   1 
ATOM 3167 O O   . GLU A 1 414  ? 163.974 103.796 178.871 1.00 88.02  ? 414  GLU A O   1 
ATOM 3168 C CB  . GLU A 1 414  ? 162.811 106.234 180.214 1.00 89.86  ? 414  GLU A CB  1 
ATOM 3169 C CG  . GLU A 1 414  ? 162.710 107.098 181.464 1.00 88.82  ? 414  GLU A CG  1 
ATOM 3170 C CD  . GLU A 1 414  ? 162.711 108.573 181.165 1.00 89.12  ? 414  GLU A CD  1 
ATOM 3171 O OE1 . GLU A 1 414  ? 162.718 108.886 180.006 1.00 88.97  ? 414  GLU A OE1 1 
ATOM 3172 O OE2 . GLU A 1 414  ? 162.703 109.393 182.101 1.00 89.39  ? 414  GLU A OE2 1 
ATOM 3173 N N   . ALA A 1 566  ? 153.463 140.876 138.259 1.00 40.55  ? 566  ALA A N   1 
ATOM 3174 C CA  . ALA A 1 566  ? 152.044 140.549 138.192 1.00 42.22  ? 566  ALA A CA  1 
ATOM 3175 C C   . ALA A 1 566  ? 151.192 141.811 138.134 1.00 43.21  ? 566  ALA A C   1 
ATOM 3176 O O   . ALA A 1 566  ? 151.713 142.925 138.082 1.00 42.78  ? 566  ALA A O   1 
ATOM 3177 C CB  . ALA A 1 566  ? 151.640 139.692 139.381 1.00 39.82  ? 566  ALA A CB  1 
ATOM 3178 N N   . GLU A 1 567  ? 149.880 141.624 138.142 1.00 44.12  ? 567  GLU A N   1 
ATOM 3179 C CA  . GLU A 1 567  ? 148.898 142.693 138.075 1.00 40.77  ? 567  GLU A CA  1 
ATOM 3180 C C   . GLU A 1 567  ? 148.266 142.872 139.441 1.00 38.25  ? 567  GLU A C   1 
ATOM 3181 O O   . GLU A 1 567  ? 147.765 141.901 140.017 1.00 41.25  ? 567  GLU A O   1 
ATOM 3182 C CB  . GLU A 1 567  ? 147.817 142.360 137.050 1.00 41.95  ? 567  GLU A CB  1 
ATOM 3183 C CG  . GLU A 1 567  ? 148.283 142.291 135.599 1.00 42.15  ? 567  GLU A CG  1 
ATOM 3184 C CD  . GLU A 1 567  ? 148.723 143.636 135.064 1.00 47.11  ? 567  GLU A CD  1 
ATOM 3185 O OE1 . GLU A 1 567  ? 148.160 144.662 135.501 1.00 44.54  ? 567  GLU A OE1 1 
ATOM 3186 O OE2 . GLU A 1 567  ? 149.633 143.673 134.209 1.00 47.49  ? 567  GLU A OE2 1 
ATOM 3187 N N   . PRO A 1 568  ? 148.279 144.066 140.015 1.00 34.65  ? 568  PRO A N   1 
ATOM 3188 C CA  . PRO A 1 568  ? 147.750 144.234 141.375 1.00 34.84  ? 568  PRO A CA  1 
ATOM 3189 C C   . PRO A 1 568  ? 146.226 144.209 141.422 1.00 32.80  ? 568  PRO A C   1 
ATOM 3190 O O   . PRO A 1 568  ? 145.536 144.462 140.434 1.00 36.43  ? 568  PRO A O   1 
ATOM 3191 C CB  . PRO A 1 568  ? 148.305 145.596 141.810 1.00 32.11  ? 568  PRO A CB  1 
ATOM 3192 C CG  . PRO A 1 568  ? 148.489 146.336 140.492 1.00 31.31  ? 568  PRO A CG  1 
ATOM 3193 C CD  . PRO A 1 568  ? 148.878 145.296 139.480 1.00 34.58  ? 568  PRO A CD  1 
ATOM 3194 N N   . GLU A 1 569  ? 145.703 143.873 142.603 1.00 24.06  ? 569  GLU A N   1 
ATOM 3195 C CA  . GLU A 1 569  ? 144.266 143.866 142.855 1.00 26.67  ? 569  GLU A CA  1 
ATOM 3196 C C   . GLU A 1 569  ? 143.898 145.206 143.481 1.00 31.65  ? 569  GLU A C   1 
ATOM 3197 O O   . GLU A 1 569  ? 144.198 145.456 144.653 1.00 29.54  ? 569  GLU A O   1 
ATOM 3198 C CB  . GLU A 1 569  ? 143.875 142.700 143.759 1.00 26.53  ? 569  GLU A CB  1 
ATOM 3199 C CG  . GLU A 1 569  ? 143.906 141.348 143.063 1.00 31.41  ? 569  GLU A CG  1 
ATOM 3200 C CD  . GLU A 1 569  ? 144.270 140.214 144.000 1.00 37.08  ? 569  GLU A CD  1 
ATOM 3201 O OE1 . GLU A 1 569  ? 145.427 139.746 143.948 1.00 33.92  ? 569  GLU A OE1 1 
ATOM 3202 O OE2 . GLU A 1 569  ? 143.399 139.789 144.787 1.00 32.31  ? 569  GLU A OE2 1 
ATOM 3203 N N   . ILE A 1 570  ? 143.258 146.062 142.699 1.00 33.38  ? 570  ILE A N   1 
ATOM 3204 C CA  . ILE A 1 570  ? 142.962 147.422 143.161 1.00 34.73  ? 570  ILE A CA  1 
ATOM 3205 C C   . ILE A 1 570  ? 141.825 147.366 144.177 1.00 33.35  ? 570  ILE A C   1 
ATOM 3206 O O   . ILE A 1 570  ? 140.779 146.746 143.897 1.00 34.49  ? 570  ILE A O   1 
ATOM 3207 C CB  . ILE A 1 570  ? 142.596 148.317 141.979 1.00 35.04  ? 570  ILE A CB  1 
ATOM 3208 C CG1 . ILE A 1 570  ? 143.763 148.382 140.995 1.00 30.94  ? 570  ILE A CG1 1 
ATOM 3209 C CG2 . ILE A 1 570  ? 142.235 149.715 142.457 1.00 31.30  ? 570  ILE A CG2 1 
ATOM 3210 C CD1 . ILE A 1 570  ? 145.027 148.924 141.597 1.00 34.05  ? 570  ILE A CD1 1 
ATOM 3211 N N   . PRO A 1 571  ? 141.969 147.973 145.356 1.00 28.14  ? 571  PRO A N   1 
ATOM 3212 C CA  . PRO A 1 571  ? 140.847 147.999 146.296 1.00 26.66  ? 571  PRO A CA  1 
ATOM 3213 C C   . PRO A 1 571  ? 139.654 148.761 145.739 1.00 28.46  ? 571  PRO A C   1 
ATOM 3214 O O   . PRO A 1 571  ? 139.797 149.742 145.008 1.00 30.87  ? 571  PRO A O   1 
ATOM 3215 C CB  . PRO A 1 571  ? 141.464 148.683 147.515 1.00 22.59  ? 571  PRO A CB  1 
ATOM 3216 C CG  . PRO A 1 571  ? 142.281 149.736 146.814 1.00 26.67  ? 571  PRO A CG  1 
ATOM 3217 C CD  . PRO A 1 571  ? 143.062 148.793 145.902 1.00 24.70  ? 571  PRO A CD  1 
ATOM 3218 N N   . LEU A 1 572  ? 138.453 148.287 146.085 1.00 27.46  ? 572  LEU A N   1 
ATOM 3219 C CA  . LEU A 1 572  ? 137.230 148.900 145.580 1.00 31.52  ? 572  LEU A CA  1 
ATOM 3220 C C   . LEU A 1 572  ? 136.929 150.241 146.234 1.00 36.77  ? 572  LEU A C   1 
ATOM 3221 O O   . LEU A 1 572  ? 136.188 151.043 145.657 1.00 38.71  ? 572  LEU A O   1 
ATOM 3222 C CB  . LEU A 1 572  ? 136.038 147.958 145.777 1.00 33.88  ? 572  LEU A CB  1 
ATOM 3223 C CG  . LEU A 1 572  ? 135.867 146.779 144.812 1.00 36.36  ? 572  LEU A CG  1 
ATOM 3224 C CD1 . LEU A 1 572  ? 136.913 145.694 145.040 1.00 32.29  ? 572  LEU A CD1 1 
ATOM 3225 C CD2 . LEU A 1 572  ? 134.463 146.201 144.917 1.00 35.10  ? 572  LEU A CD2 1 
ATOM 3226 N N   . SER A 1 573  ? 137.488 150.504 147.414 1.00 34.44  ? 573  SER A N   1 
ATOM 3227 C CA  . SER A 1 573  ? 137.238 151.755 148.115 1.00 33.66  ? 573  SER A CA  1 
ATOM 3228 C C   . SER A 1 573  ? 138.048 152.919 147.561 1.00 34.12  ? 573  SER A C   1 
ATOM 3229 O O   . SER A 1 573  ? 137.849 154.055 148.006 1.00 36.25  ? 573  SER A O   1 
ATOM 3230 C CB  . SER A 1 573  ? 137.532 151.589 149.608 1.00 34.16  ? 573  SER A CB  1 
ATOM 3231 O OG  . SER A 1 573  ? 136.650 150.651 150.199 1.00 35.50  ? 573  SER A OG  1 
ATOM 3232 N N   . LEU A 1 574  ? 138.957 152.666 146.624 1.00 33.06  ? 574  LEU A N   1 
ATOM 3233 C CA  . LEU A 1 574  ? 139.721 153.740 146.005 1.00 33.17  ? 574  LEU A CA  1 
ATOM 3234 C C   . LEU A 1 574  ? 138.790 154.654 145.217 1.00 34.60  ? 574  LEU A C   1 
ATOM 3235 O O   . LEU A 1 574  ? 137.935 154.182 144.462 1.00 36.96  ? 574  LEU A O   1 
ATOM 3236 C CB  . LEU A 1 574  ? 140.799 153.158 145.092 1.00 32.67  ? 574  LEU A CB  1 
ATOM 3237 C CG  . LEU A 1 574  ? 141.865 154.104 144.538 1.00 31.73  ? 574  LEU A CG  1 
ATOM 3238 C CD1 . LEU A 1 574  ? 142.360 155.054 145.613 1.00 31.23  ? 574  LEU A CD1 1 
ATOM 3239 C CD2 . LEU A 1 574  ? 143.019 153.312 143.948 1.00 33.11  ? 574  LEU A CD2 1 
ATOM 3240 N N   . LYS A 1 575  ? 138.952 155.962 145.396 1.00 35.58  ? 575  LYS A N   1 
ATOM 3241 C CA  . LYS A 1 575  ? 138.080 156.917 144.728 1.00 35.32  ? 575  LYS A CA  1 
ATOM 3242 C C   . LYS A 1 575  ? 138.324 156.910 143.224 1.00 42.08  ? 575  LYS A C   1 
ATOM 3243 O O   . LYS A 1 575  ? 139.451 156.716 142.760 1.00 45.04  ? 575  LYS A O   1 
ATOM 3244 C CB  . LYS A 1 575  ? 138.289 158.321 145.295 1.00 37.80  ? 575  LYS A CB  1 
ATOM 3245 C CG  . LYS A 1 575  ? 137.821 158.476 146.733 1.00 37.43  ? 575  LYS A CG  1 
ATOM 3246 C CD  . LYS A 1 575  ? 138.024 159.894 147.235 1.00 35.31  ? 575  LYS A CD  1 
ATOM 3247 C CE  . LYS A 1 575  ? 137.574 160.034 148.679 1.00 37.84  ? 575  LYS A CE  1 
ATOM 3248 N NZ  . LYS A 1 575  ? 137.777 161.415 149.195 1.00 39.35  ? 575  LYS A NZ  1 
ATOM 3249 N N   . GLU A 1 576  ? 137.249 157.128 142.462 1.00 50.68  ? 576  GLU A N   1 
ATOM 3250 C CA  . GLU A 1 576  ? 137.313 157.018 141.010 1.00 50.24  ? 576  GLU A CA  1 
ATOM 3251 C C   . GLU A 1 576  ? 138.187 158.086 140.370 1.00 49.33  ? 576  GLU A C   1 
ATOM 3252 O O   . GLU A 1 576  ? 138.700 157.866 139.268 1.00 47.00  ? 576  GLU A O   1 
ATOM 3253 C CB  . GLU A 1 576  ? 135.903 157.082 140.417 1.00 49.70  ? 576  GLU A CB  1 
ATOM 3254 C CG  . GLU A 1 576  ? 134.982 155.957 140.867 1.00 51.43  ? 576  GLU A CG  1 
ATOM 3255 C CD  . GLU A 1 576  ? 135.568 154.581 140.614 1.00 50.83  ? 576  GLU A CD  1 
ATOM 3256 O OE1 . GLU A 1 576  ? 135.104 153.611 141.248 1.00 51.34  ? 576  GLU A OE1 1 
ATOM 3257 O OE2 . GLU A 1 576  ? 136.489 154.463 139.777 1.00 50.37  ? 576  GLU A OE2 1 
ATOM 3258 N N   . HIS A 1 577  ? 138.367 159.227 141.025 1.00 51.80  ? 577  HIS A N   1 
ATOM 3259 C CA  . HIS A 1 577  ? 139.174 160.306 140.477 1.00 50.84  ? 577  HIS A CA  1 
ATOM 3260 C C   . HIS A 1 577  ? 140.661 160.126 140.743 1.00 48.84  ? 577  HIS A C   1 
ATOM 3261 O O   . HIS A 1 577  ? 141.460 160.962 140.310 1.00 48.69  ? 577  HIS A O   1 
ATOM 3262 C CB  . HIS A 1 577  ? 138.697 161.655 141.031 1.00 51.87  ? 577  HIS A CB  1 
ATOM 3263 C CG  . HIS A 1 577  ? 139.403 162.090 142.278 1.00 51.46  ? 577  HIS A CG  1 
ATOM 3264 N ND1 . HIS A 1 577  ? 138.942 161.782 143.540 1.00 51.85  ? 577  HIS A ND1 1 
ATOM 3265 C CD2 . HIS A 1 577  ? 140.514 162.841 142.458 1.00 51.62  ? 577  HIS A CD2 1 
ATOM 3266 C CE1 . HIS A 1 577  ? 139.751 162.304 144.444 1.00 51.89  ? 577  HIS A CE1 1 
ATOM 3267 N NE2 . HIS A 1 577  ? 140.706 162.961 143.813 1.00 53.91  ? 577  HIS A NE2 1 
ATOM 3268 N N   . ILE A 1 578  ? 141.053 159.057 141.430 1.00 49.53  ? 578  ILE A N   1 
ATOM 3269 C CA  . ILE A 1 578  ? 142.444 158.806 141.782 1.00 50.36  ? 578  ILE A CA  1 
ATOM 3270 C C   . ILE A 1 578  ? 142.913 157.558 141.051 1.00 48.45  ? 578  ILE A C   1 
ATOM 3271 O O   . ILE A 1 578  ? 142.282 156.499 141.145 1.00 47.15  ? 578  ILE A O   1 
ATOM 3272 C CB  . ILE A 1 578  ? 142.615 158.660 143.302 1.00 49.47  ? 578  ILE A CB  1 
ATOM 3273 C CG1 . ILE A 1 578  ? 142.145 159.935 143.998 1.00 46.68  ? 578  ILE A CG1 1 
ATOM 3274 C CG2 . ILE A 1 578  ? 144.066 158.351 143.652 1.00 48.65  ? 578  ILE A CG2 1 
ATOM 3275 C CD1 . ILE A 1 578  ? 142.939 161.149 143.591 1.00 46.04  ? 578  ILE A CD1 1 
ATOM 3276 N N   . ARG A 1 579  ? 144.018 157.688 140.323 1.00 47.23  ? 579  ARG A N   1 
ATOM 3277 C CA  . ARG A 1 579  ? 144.601 156.596 139.561 1.00 47.62  ? 579  ARG A CA  1 
ATOM 3278 C C   . ARG A 1 579  ? 146.045 156.396 139.993 1.00 46.93  ? 579  ARG A C   1 
ATOM 3279 O O   . ARG A 1 579  ? 146.751 157.360 140.303 1.00 47.97  ? 579  ARG A O   1 
ATOM 3280 C CB  . ARG A 1 579  ? 144.534 156.879 138.053 1.00 47.32  ? 579  ARG A CB  1 
ATOM 3281 C CG  . ARG A 1 579  ? 145.157 155.807 137.165 1.00 48.41  ? 579  ARG A CG  1 
ATOM 3282 C CD  . ARG A 1 579  ? 144.327 154.530 137.154 1.00 48.99  ? 579  ARG A CD  1 
ATOM 3283 N NE  . ARG A 1 579  ? 144.652 153.648 138.268 1.00 52.39  ? 579  ARG A NE  1 
ATOM 3284 C CZ  . ARG A 1 579  ? 143.972 152.554 138.583 1.00 52.21  ? 579  ARG A CZ  1 
ATOM 3285 N NH1 . ARG A 1 579  ? 142.929 152.160 137.871 1.00 51.12  ? 579  ARG A NH1 1 
ATOM 3286 N NH2 . ARG A 1 579  ? 144.348 151.838 139.639 1.00 47.60  ? 579  ARG A NH2 1 
ATOM 3287 N N   . LEU A 1 580  ? 146.475 155.140 140.022 1.00 38.91  ? 580  LEU A N   1 
ATOM 3288 C CA  . LEU A 1 580  ? 147.852 154.826 140.358 1.00 38.39  ? 580  LEU A CA  1 
ATOM 3289 C C   . LEU A 1 580  ? 148.742 155.010 139.140 1.00 39.30  ? 580  LEU A C   1 
ATOM 3290 O O   . LEU A 1 580  ? 148.378 154.629 138.024 1.00 42.37  ? 580  LEU A O   1 
ATOM 3291 C CB  . LEU A 1 580  ? 147.970 153.390 140.863 1.00 41.10  ? 580  LEU A CB  1 
ATOM 3292 C CG  . LEU A 1 580  ? 147.310 153.033 142.191 1.00 40.27  ? 580  LEU A CG  1 
ATOM 3293 C CD1 . LEU A 1 580  ? 147.246 151.530 142.341 1.00 35.61  ? 580  LEU A CD1 1 
ATOM 3294 C CD2 . LEU A 1 580  ? 148.090 153.643 143.327 1.00 38.41  ? 580  LEU A CD2 1 
ATOM 3295 N N   . LYS A 1 581  ? 149.914 155.601 139.359 1.00 35.81  ? 581  LYS A N   1 
ATOM 3296 C CA  . LYS A 1 581  ? 150.953 155.565 138.346 1.00 34.92  ? 581  LYS A CA  1 
ATOM 3297 C C   . LYS A 1 581  ? 151.319 154.117 138.046 1.00 33.77  ? 581  LYS A C   1 
ATOM 3298 O O   . LYS A 1 581  ? 150.972 153.197 138.791 1.00 36.56  ? 581  LYS A O   1 
ATOM 3299 C CB  . LYS A 1 581  ? 152.188 156.337 138.811 1.00 35.10  ? 581  LYS A CB  1 
ATOM 3300 C CG  . LYS A 1 581  ? 151.936 157.809 139.065 1.00 34.35  ? 581  LYS A CG  1 
ATOM 3301 C CD  . LYS A 1 581  ? 151.624 158.516 137.760 1.00 37.76  ? 581  LYS A CD  1 
ATOM 3302 C CE  . LYS A 1 581  ? 151.438 160.007 137.951 1.00 39.78  ? 581  LYS A CE  1 
ATOM 3303 N NZ  . LYS A 1 581  ? 151.091 160.682 136.671 1.00 40.33  ? 581  LYS A NZ  1 
ATOM 3304 N N   . ASP A 1 582  ? 152.018 153.910 136.929 1.00 38.19  ? 582  ASP A N   1 
ATOM 3305 C CA  . ASP A 1 582  ? 152.473 152.561 136.614 1.00 34.55  ? 582  ASP A CA  1 
ATOM 3306 C C   . ASP A 1 582  ? 153.309 152.001 137.756 1.00 36.57  ? 582  ASP A C   1 
ATOM 3307 O O   . ASP A 1 582  ? 152.936 151.002 138.390 1.00 40.79  ? 582  ASP A O   1 
ATOM 3308 C CB  . ASP A 1 582  ? 153.273 152.558 135.312 1.00 33.63  ? 582  ASP A CB  1 
ATOM 3309 C CG  . ASP A 1 582  ? 152.390 152.499 134.086 1.00 40.13  ? 582  ASP A CG  1 
ATOM 3310 O OD1 . ASP A 1 582  ? 152.256 153.537 133.406 1.00 42.41  ? 582  ASP A OD1 1 
ATOM 3311 O OD2 . ASP A 1 582  ? 151.825 151.420 133.805 1.00 42.32  ? 582  ASP A OD2 1 
ATOM 3312 N N   . HIS A 1 583  ? 154.414 152.679 138.074 1.00 31.20  ? 583  HIS A N   1 
ATOM 3313 C CA  . HIS A 1 583  ? 155.348 152.172 139.072 1.00 28.63  ? 583  HIS A CA  1 
ATOM 3314 C C   . HIS A 1 583  ? 154.662 151.941 140.409 1.00 32.11  ? 583  HIS A C   1 
ATOM 3315 O O   . HIS A 1 583  ? 154.987 150.980 141.115 1.00 34.57  ? 583  HIS A O   1 
ATOM 3316 C CB  . HIS A 1 583  ? 156.526 153.136 139.218 1.00 28.85  ? 583  HIS A CB  1 
ATOM 3317 C CG  . HIS A 1 583  ? 156.196 154.403 139.945 1.00 31.61  ? 583  HIS A CG  1 
ATOM 3318 N ND1 . HIS A 1 583  ? 155.639 155.494 139.315 1.00 36.77  ? 583  HIS A ND1 1 
ATOM 3319 C CD2 . HIS A 1 583  ? 156.334 154.750 141.247 1.00 30.25  ? 583  HIS A CD2 1 
ATOM 3320 C CE1 . HIS A 1 583  ? 155.448 156.459 140.196 1.00 31.22  ? 583  HIS A CE1 1 
ATOM 3321 N NE2 . HIS A 1 583  ? 155.863 156.034 141.376 1.00 33.85  ? 583  HIS A NE2 1 
ATOM 3322 N N   . GLN A 1 584  ? 153.687 152.782 140.750 1.00 29.06  ? 584  GLN A N   1 
ATOM 3323 C CA  . GLN A 1 584  ? 152.885 152.536 141.939 1.00 26.08  ? 584  GLN A CA  1 
ATOM 3324 C C   . GLN A 1 584  ? 152.098 151.237 141.807 1.00 22.19  ? 584  GLN A C   1 
ATOM 3325 O O   . GLN A 1 584  ? 151.950 150.494 142.785 1.00 31.72  ? 584  GLN A O   1 
ATOM 3326 C CB  . GLN A 1 584  ? 151.961 153.727 142.187 1.00 24.39  ? 584  GLN A CB  1 
ATOM 3327 C CG  . GLN A 1 584  ? 152.707 155.057 142.253 1.00 21.96  ? 584  GLN A CG  1 
ATOM 3328 C CD  . GLN A 1 584  ? 151.900 156.158 142.907 1.00 28.79  ? 584  GLN A CD  1 
ATOM 3329 O OE1 . GLN A 1 584  ? 150.698 156.016 143.120 1.00 31.93  ? 584  GLN A OE1 1 
ATOM 3330 N NE2 . GLN A 1 584  ? 152.560 157.264 143.232 1.00 31.54  ? 584  GLN A NE2 1 
ATOM 3331 N N   . ARG A 1 585  ? 151.601 150.935 140.604 1.00 22.60  ? 585  ARG A N   1 
ATOM 3332 C CA  . ARG A 1 585  ? 150.890 149.676 140.404 1.00 22.83  ? 585  ARG A CA  1 
ATOM 3333 C C   . ARG A 1 585  ? 151.809 148.472 140.602 1.00 25.05  ? 585  ARG A C   1 
ATOM 3334 O O   . ARG A 1 585  ? 151.425 147.508 141.275 1.00 26.69  ? 585  ARG A O   1 
ATOM 3335 C CB  . ARG A 1 585  ? 150.230 149.634 139.023 1.00 28.28  ? 585  ARG A CB  1 
ATOM 3336 C CG  . ARG A 1 585  ? 149.102 150.639 138.825 1.00 31.78  ? 585  ARG A CG  1 
ATOM 3337 C CD  . ARG A 1 585  ? 148.536 150.569 137.414 1.00 32.92  ? 585  ARG A CD  1 
ATOM 3338 N NE  . ARG A 1 585  ? 147.897 149.288 137.142 1.00 32.97  ? 585  ARG A NE  1 
ATOM 3339 C CZ  . ARG A 1 585  ? 146.626 149.021 137.407 1.00 34.52  ? 585  ARG A CZ  1 
ATOM 3340 N NH1 . ARG A 1 585  ? 145.835 149.922 137.963 1.00 31.18  ? 585  ARG A NH1 1 
ATOM 3341 N NH2 . ARG A 1 585  ? 146.137 147.822 137.106 1.00 32.98  ? 585  ARG A NH2 1 
ATOM 3342 N N   . GLU A 1 586  ? 153.027 148.492 140.038 1.00 26.25  ? 586  GLU A N   1 
ATOM 3343 C CA  . GLU A 1 586  ? 153.909 147.345 140.281 1.00 22.70  ? 586  GLU A CA  1 
ATOM 3344 C C   . GLU A 1 586  ? 154.315 147.267 141.744 1.00 19.57  ? 586  GLU A C   1 
ATOM 3345 O O   . GLU A 1 586  ? 154.492 146.172 142.280 1.00 24.69  ? 586  GLU A O   1 
ATOM 3346 C CB  . GLU A 1 586  ? 155.164 147.367 139.399 1.00 26.92  ? 586  GLU A CB  1 
ATOM 3347 C CG  . GLU A 1 586  ? 156.106 146.151 139.591 1.00 28.98  ? 586  GLU A CG  1 
ATOM 3348 C CD  . GLU A 1 586  ? 155.454 144.871 139.163 1.00 33.68  ? 586  GLU A CD  1 
ATOM 3349 O OE1 . GLU A 1 586  ? 154.553 144.963 138.310 1.00 31.18  ? 586  GLU A OE1 1 
ATOM 3350 O OE2 . GLU A 1 586  ? 155.825 143.788 139.659 1.00 32.50  ? 586  GLU A OE2 1 
ATOM 3351 N N   . GLY A 1 587  ? 154.485 148.414 142.406 1.00 18.40  ? 587  GLY A N   1 
ATOM 3352 C CA  . GLY A 1 587  ? 154.801 148.383 143.825 1.00 14.20  ? 587  GLY A CA  1 
ATOM 3353 C C   . GLY A 1 587  ? 153.705 147.730 144.645 1.00 10.73  ? 587  GLY A C   1 
ATOM 3354 O O   . GLY A 1 587  ? 153.976 146.880 145.502 1.00 19.54  ? 587  GLY A O   1 
ATOM 3355 N N   . VAL A 1 588  ? 152.452 148.100 144.377 1.00 11.48  ? 588  VAL A N   1 
ATOM 3356 C CA  . VAL A 1 588  ? 151.332 147.472 145.070 1.00 10.39  ? 588  VAL A CA  1 
ATOM 3357 C C   . VAL A 1 588  ? 151.291 145.979 144.771 1.00 11.79  ? 588  VAL A C   1 
ATOM 3358 O O   . VAL A 1 588  ? 151.122 145.160 145.679 1.00 17.94  ? 588  VAL A O   1 
ATOM 3359 C CB  . VAL A 1 588  ? 150.007 148.163 144.697 1.00 11.24  ? 588  VAL A CB  1 
ATOM 3360 C CG1 . VAL A 1 588  ? 148.835 147.441 145.334 1.00 6.59   ? 588  VAL A CG1 1 
ATOM 3361 C CG2 . VAL A 1 588  ? 150.030 149.614 145.136 1.00 14.14  ? 588  VAL A CG2 1 
ATOM 3362 N N   . ALA A 1 589  ? 151.460 145.602 143.499 1.00 14.57  ? 589  ALA A N   1 
ATOM 3363 C CA  . ALA A 1 589  ? 151.405 144.190 143.126 1.00 3.49   ? 589  ALA A CA  1 
ATOM 3364 C C   . ALA A 1 589  ? 152.511 143.390 143.801 1.00 6.09   ? 589  ALA A C   1 
ATOM 3365 O O   . ALA A 1 589  ? 152.289 142.258 144.242 1.00 17.99  ? 589  ALA A O   1 
ATOM 3366 C CB  . ALA A 1 589  ? 151.497 144.043 141.609 1.00 16.98  ? 589  ALA A CB  1 
ATOM 3367 N N   . TRP A 1 590  ? 153.714 143.957 143.871 1.00 8.55   ? 590  TRP A N   1 
ATOM 3368 C CA  . TRP A 1 590  ? 154.829 143.304 144.545 1.00 5.15   ? 590  TRP A CA  1 
ATOM 3369 C C   . TRP A 1 590  ? 154.528 143.122 146.025 1.00 10.97  ? 590  TRP A C   1 
ATOM 3370 O O   . TRP A 1 590  ? 154.803 142.063 146.605 1.00 12.10  ? 590  TRP A O   1 
ATOM 3371 C CB  . TRP A 1 590  ? 156.092 144.140 144.332 1.00 5.76   ? 590  TRP A CB  1 
ATOM 3372 C CG  . TRP A 1 590  ? 157.300 143.734 145.114 1.00 8.41   ? 590  TRP A CG  1 
ATOM 3373 C CD1 . TRP A 1 590  ? 158.211 142.778 144.775 1.00 5.36   ? 590  TRP A CD1 1 
ATOM 3374 C CD2 . TRP A 1 590  ? 157.755 144.301 146.348 1.00 11.88  ? 590  TRP A CD2 1 
ATOM 3375 N NE1 . TRP A 1 590  ? 159.196 142.704 145.727 1.00 4.08   ? 590  TRP A NE1 1 
ATOM 3376 C CE2 . TRP A 1 590  ? 158.942 143.633 146.701 1.00 7.47   ? 590  TRP A CE2 1 
ATOM 3377 C CE3 . TRP A 1 590  ? 157.271 145.305 147.192 1.00 7.99   ? 590  TRP A CE3 1 
ATOM 3378 C CZ2 . TRP A 1 590  ? 159.655 143.938 147.859 1.00 5.92   ? 590  TRP A CZ2 1 
ATOM 3379 C CZ3 . TRP A 1 590  ? 157.974 145.598 148.340 1.00 7.46   ? 590  TRP A CZ3 1 
ATOM 3380 C CH2 . TRP A 1 590  ? 159.149 144.916 148.667 1.00 7.14   ? 590  TRP A CH2 1 
ATOM 3381 N N   . LEU A 1 591  ? 153.938 144.147 146.647 1.00 13.96  ? 591  LEU A N   1 
ATOM 3382 C CA  . LEU A 1 591  ? 153.540 144.036 148.046 1.00 1.46   ? 591  LEU A CA  1 
ATOM 3383 C C   . LEU A 1 591  ? 152.541 142.905 148.250 1.00 1.69   ? 591  LEU A C   1 
ATOM 3384 O O   . LEU A 1 591  ? 152.698 142.084 149.162 1.00 15.63  ? 591  LEU A O   1 
ATOM 3385 C CB  . LEU A 1 591  ? 152.950 145.362 148.520 1.00 4.41   ? 591  LEU A CB  1 
ATOM 3386 C CG  . LEU A 1 591  ? 153.920 146.357 149.152 1.00 5.77   ? 591  LEU A CG  1 
ATOM 3387 C CD1 . LEU A 1 591  ? 153.159 147.525 149.744 1.00 8.39   ? 591  LEU A CD1 1 
ATOM 3388 C CD2 . LEU A 1 591  ? 154.757 145.673 150.209 1.00 7.35   ? 591  LEU A CD2 1 
ATOM 3389 N N   . GLN A 1 592  ? 151.509 142.838 147.404 1.00 4.67   ? 592  GLN A N   1 
ATOM 3390 C CA  . GLN A 1 592  ? 150.514 141.777 147.547 1.00 4.48   ? 592  GLN A CA  1 
ATOM 3391 C C   . GLN A 1 592  ? 151.131 140.404 147.323 1.00 6.22   ? 592  GLN A C   1 
ATOM 3392 O O   . GLN A 1 592  ? 150.846 139.462 148.069 1.00 13.07  ? 592  GLN A O   1 
ATOM 3393 C CB  . GLN A 1 592  ? 149.341 141.989 146.587 1.00 4.44   ? 592  GLN A CB  1 
ATOM 3394 C CG  . GLN A 1 592  ? 148.936 143.427 146.386 1.00 8.76   ? 592  GLN A CG  1 
ATOM 3395 C CD  . GLN A 1 592  ? 147.560 143.579 145.781 1.00 15.90  ? 592  GLN A CD  1 
ATOM 3396 O OE1 . GLN A 1 592  ? 147.263 143.009 144.732 1.00 19.97  ? 592  GLN A OE1 1 
ATOM 3397 N NE2 . GLN A 1 592  ? 146.721 144.379 146.422 1.00 12.33  ? 592  GLN A NE2 1 
ATOM 3398 N N   . GLN A 1 593  ? 151.979 140.266 146.304 1.00 8.41   ? 593  GLN A N   1 
ATOM 3399 C CA  . GLN A 1 593  ? 152.563 138.962 146.015 1.00 8.11   ? 593  GLN A CA  1 
ATOM 3400 C C   . GLN A 1 593  ? 153.488 138.504 147.132 1.00 10.75  ? 593  GLN A C   1 
ATOM 3401 O O   . GLN A 1 593  ? 153.582 137.301 147.401 1.00 14.55  ? 593  GLN A O   1 
ATOM 3402 C CB  . GLN A 1 593  ? 153.303 138.997 144.678 1.00 7.02   ? 593  GLN A CB  1 
ATOM 3403 C CG  . GLN A 1 593  ? 152.390 139.232 143.485 1.00 12.82  ? 593  GLN A CG  1 
ATOM 3404 C CD  . GLN A 1 593  ? 151.367 138.126 143.301 1.00 23.44  ? 593  GLN A CD  1 
ATOM 3405 O OE1 . GLN A 1 593  ? 150.174 138.323 143.532 1.00 17.33  ? 593  GLN A OE1 1 
ATOM 3406 N NE2 . GLN A 1 593  ? 151.831 136.956 142.878 1.00 22.57  ? 593  GLN A NE2 1 
ATOM 3407 N N   . LEU A 1 594  ? 154.180 139.437 147.788 1.00 13.80  ? 594  LEU A N   1 
ATOM 3408 C CA  . LEU A 1 594  ? 154.903 139.080 149.004 1.00 5.57   ? 594  LEU A CA  1 
ATOM 3409 C C   . LEU A 1 594  ? 153.942 138.681 150.117 1.00 7.20   ? 594  LEU A C   1 
ATOM 3410 O O   . LEU A 1 594  ? 154.218 137.747 150.878 1.00 13.83  ? 594  LEU A O   1 
ATOM 3411 C CB  . LEU A 1 594  ? 155.791 140.239 149.448 1.00 4.62   ? 594  LEU A CB  1 
ATOM 3412 C CG  . LEU A 1 594  ? 156.940 140.585 148.506 1.00 4.75   ? 594  LEU A CG  1 
ATOM 3413 C CD1 . LEU A 1 594  ? 157.633 141.810 148.993 1.00 6.79   ? 594  LEU A CD1 1 
ATOM 3414 C CD2 . LEU A 1 594  ? 157.912 139.433 148.433 1.00 10.70  ? 594  LEU A CD2 1 
ATOM 3415 N N   . PHE A 1 595  ? 152.804 139.374 150.225 1.00 7.04   ? 595  PHE A N   1 
ATOM 3416 C CA  . PHE A 1 595  ? 151.885 139.116 151.329 1.00 1.97   ? 595  PHE A CA  1 
ATOM 3417 C C   . PHE A 1 595  ? 151.192 137.761 151.220 1.00 6.41   ? 595  PHE A C   1 
ATOM 3418 O O   . PHE A 1 595  ? 150.938 137.122 152.245 1.00 15.90  ? 595  PHE A O   1 
ATOM 3419 C CB  . PHE A 1 595  ? 150.827 140.207 151.409 1.00 5.85   ? 595  PHE A CB  1 
ATOM 3420 C CG  . PHE A 1 595  ? 150.039 140.179 152.679 1.00 11.84  ? 595  PHE A CG  1 
ATOM 3421 C CD1 . PHE A 1 595  ? 148.727 139.749 152.682 1.00 9.24   ? 595  PHE A CD1 1 
ATOM 3422 C CD2 . PHE A 1 595  ? 150.599 140.610 153.862 1.00 13.10  ? 595  PHE A CD2 1 
ATOM 3423 C CE1 . PHE A 1 595  ? 148.008 139.722 153.844 1.00 14.61  ? 595  PHE A CE1 1 
ATOM 3424 C CE2 . PHE A 1 595  ? 149.874 140.595 155.028 1.00 9.93   ? 595  PHE A CE2 1 
ATOM 3425 C CZ  . PHE A 1 595  ? 148.576 140.154 155.021 1.00 15.06  ? 595  PHE A CZ  1 
ATOM 3426 N N   . LEU A 1 596  ? 150.845 137.316 150.010 1.00 11.57  ? 596  LEU A N   1 
ATOM 3427 C CA  . LEU A 1 596  ? 150.153 136.036 149.888 1.00 7.96   ? 596  LEU A CA  1 
ATOM 3428 C C   . LEU A 1 596  ? 151.007 134.855 150.327 1.00 9.02   ? 596  LEU A C   1 
ATOM 3429 O O   . LEU A 1 596  ? 150.465 133.764 150.533 1.00 16.53  ? 596  LEU A O   1 
ATOM 3430 C CB  . LEU A 1 596  ? 149.657 135.805 148.456 1.00 10.65  ? 596  LEU A CB  1 
ATOM 3431 C CG  . LEU A 1 596  ? 148.323 136.424 148.017 1.00 9.16   ? 596  LEU A CG  1 
ATOM 3432 C CD1 . LEU A 1 596  ? 147.185 135.825 148.826 1.00 13.11  ? 596  LEU A CD1 1 
ATOM 3433 C CD2 . LEU A 1 596  ? 148.291 137.927 148.117 1.00 6.54   ? 596  LEU A CD2 1 
ATOM 3434 N N   . ARG A 1 597  ? 152.317 135.038 150.476 1.00 8.45   ? 597  ARG A N   1 
ATOM 3435 C CA  . ARG A 1 597  ? 153.190 134.018 151.043 1.00 14.95  ? 597  ARG A CA  1 
ATOM 3436 C C   . ARG A 1 597  ? 153.847 134.512 152.328 1.00 21.00  ? 597  ARG A C   1 
ATOM 3437 O O   . ARG A 1 597  ? 154.985 134.153 152.636 1.00 21.12  ? 597  ARG A O   1 
ATOM 3438 C CB  . ARG A 1 597  ? 154.227 133.568 150.013 1.00 13.62  ? 597  ARG A CB  1 
ATOM 3439 C CG  . ARG A 1 597  ? 155.255 134.612 149.589 1.00 13.59  ? 597  ARG A CG  1 
ATOM 3440 C CD  . ARG A 1 597  ? 156.122 134.038 148.480 1.00 14.09  ? 597  ARG A CD  1 
ATOM 3441 N NE  . ARG A 1 597  ? 157.204 134.914 148.047 1.00 16.69  ? 597  ARG A NE  1 
ATOM 3442 C CZ  . ARG A 1 597  ? 157.089 135.849 147.113 1.00 23.10  ? 597  ARG A CZ  1 
ATOM 3443 N NH1 . ARG A 1 597  ? 155.930 136.100 146.527 1.00 20.54  ? 597  ARG A NH1 1 
ATOM 3444 N NH2 . ARG A 1 597  ? 158.165 136.540 146.751 1.00 20.05  ? 597  ARG A NH2 1 
ATOM 3445 N N   . SER A 1 598  ? 153.111 135.321 153.110 1.00 18.62  ? 598  SER A N   1 
ATOM 3446 C CA  . SER A 1 598  ? 153.727 135.997 154.253 1.00 11.19  ? 598  SER A CA  1 
ATOM 3447 C C   . SER A 1 598  ? 153.969 135.079 155.446 1.00 22.30  ? 598  SER A C   1 
ATOM 3448 O O   . SER A 1 598  ? 155.115 135.009 155.924 1.00 25.46  ? 598  SER A O   1 
ATOM 3449 C CB  . SER A 1 598  ? 152.906 137.232 154.637 1.00 11.06  ? 598  SER A CB  1 
ATOM 3450 O OG  . SER A 1 598  ? 151.526 136.940 154.747 1.00 21.79  ? 598  SER A OG  1 
ATOM 3451 N N   . PRO A 1 599  ? 152.970 134.365 155.986 1.00 30.05  ? 599  PRO A N   1 
ATOM 3452 C CA  . PRO A 1 599  ? 153.211 133.659 157.256 1.00 21.16  ? 599  PRO A CA  1 
ATOM 3453 C C   . PRO A 1 599  ? 154.186 132.502 157.138 1.00 25.73  ? 599  PRO A C   1 
ATOM 3454 O O   . PRO A 1 599  ? 154.680 132.028 158.169 1.00 31.32  ? 599  PRO A O   1 
ATOM 3455 C CB  . PRO A 1 599  ? 151.817 133.174 157.671 1.00 20.01  ? 599  PRO A CB  1 
ATOM 3456 C CG  . PRO A 1 599  ? 151.017 133.140 156.431 1.00 26.33  ? 599  PRO A CG  1 
ATOM 3457 C CD  . PRO A 1 599  ? 151.694 133.954 155.370 1.00 19.58  ? 599  PRO A CD  1 
ATOM 3458 N N   . GLU A 1 600  ? 154.487 132.039 155.927 1.00 24.69  ? 600  GLU A N   1 
ATOM 3459 C CA  . GLU A 1 600  ? 155.350 130.882 155.729 1.00 24.56  ? 600  GLU A CA  1 
ATOM 3460 C C   . GLU A 1 600  ? 156.745 131.253 155.239 1.00 29.59  ? 600  GLU A C   1 
ATOM 3461 O O   . GLU A 1 600  ? 157.739 130.774 155.792 1.00 30.49  ? 600  GLU A O   1 
ATOM 3462 C CB  . GLU A 1 600  ? 154.693 129.906 154.747 1.00 24.57  ? 600  GLU A CB  1 
ATOM 3463 C CG  . GLU A 1 600  ? 153.440 129.242 155.293 1.00 27.05  ? 600  GLU A CG  1 
ATOM 3464 C CD  . GLU A 1 600  ? 152.169 129.926 154.835 1.00 31.88  ? 600  GLU A CD  1 
ATOM 3465 O OE1 . GLU A 1 600  ? 152.204 130.614 153.793 1.00 33.43  ? 600  GLU A OE1 1 
ATOM 3466 O OE2 . GLU A 1 600  ? 151.135 129.778 155.519 1.00 32.60  ? 600  GLU A OE2 1 
ATOM 3467 N N   . GLU A 1 601  ? 156.848 132.098 154.214 1.00 24.18  ? 601  GLU A N   1 
ATOM 3468 C CA  . GLU A 1 601  ? 158.131 132.392 153.587 1.00 20.96  ? 601  GLU A CA  1 
ATOM 3469 C C   . GLU A 1 601  ? 158.602 133.824 153.796 1.00 20.13  ? 601  GLU A C   1 
ATOM 3470 O O   . GLU A 1 601  ? 159.791 134.048 154.040 1.00 22.52  ? 601  GLU A O   1 
ATOM 3471 C CB  . GLU A 1 601  ? 158.058 132.078 152.083 1.00 19.82  ? 601  GLU A CB  1 
ATOM 3472 C CG  . GLU A 1 601  ? 159.211 132.644 151.266 1.00 23.28  ? 601  GLU A CG  1 
ATOM 3473 C CD  . GLU A 1 601  ? 158.918 132.666 149.780 1.00 28.38  ? 601  GLU A CD  1 
ATOM 3474 O OE1 . GLU A 1 601  ? 158.049 131.887 149.337 1.00 27.50  ? 601  GLU A OE1 1 
ATOM 3475 O OE2 . GLU A 1 601  ? 159.551 133.464 149.056 1.00 22.25  ? 601  GLU A OE2 1 
ATOM 3476 N N   . THR A 1 602  ? 157.708 134.808 153.713 1.00 17.96  ? 602  THR A N   1 
ATOM 3477 C CA  . THR A 1 602  ? 158.092 136.220 153.731 1.00 17.18  ? 602  THR A CA  1 
ATOM 3478 C C   . THR A 1 602  ? 157.518 136.896 154.974 1.00 14.37  ? 602  THR A C   1 
ATOM 3479 O O   . THR A 1 602  ? 156.357 137.313 154.982 1.00 17.68  ? 602  THR A O   1 
ATOM 3480 C CB  . THR A 1 602  ? 157.620 136.923 152.462 1.00 6.95   ? 602  THR A CB  1 
ATOM 3481 O OG1 . THR A 1 602  ? 156.192 136.862 152.384 1.00 11.73  ? 602  THR A OG1 1 
ATOM 3482 C CG2 . THR A 1 602  ? 158.202 136.246 151.239 1.00 13.31  ? 602  THR A CG2 1 
ATOM 3483 N N   . ALA A 1 603  ? 158.340 137.041 156.015 1.00 10.95  ? 603  ALA A N   1 
ATOM 3484 C CA  . ALA A 1 603  ? 157.877 137.692 157.235 1.00 6.28   ? 603  ALA A CA  1 
ATOM 3485 C C   . ALA A 1 603  ? 157.662 139.189 157.054 1.00 3.53   ? 603  ALA A C   1 
ATOM 3486 O O   . ALA A 1 603  ? 156.953 139.802 157.859 1.00 9.45   ? 603  ALA A O   1 
ATOM 3487 C CB  . ALA A 1 603  ? 158.869 137.446 158.372 1.00 5.70   ? 603  ALA A CB  1 
ATOM 3488 N N   . GLY A 1 604  ? 158.245 139.786 156.023 1.00 1.47   ? 604  GLY A N   1 
ATOM 3489 C CA  . GLY A 1 604  ? 158.131 141.218 155.839 1.00 0.00   ? 604  GLY A CA  1 
ATOM 3490 C C   . GLY A 1 604  ? 158.729 141.639 154.518 1.00 1.23   ? 604  GLY A C   1 
ATOM 3491 O O   . GLY A 1 604  ? 158.868 140.826 153.603 1.00 10.26  ? 604  GLY A O   1 
ATOM 3492 N N   . CYS A 1 605  ? 159.074 142.921 154.418 1.00 4.93   ? 605  CYS A N   1 
ATOM 3493 C CA  . CYS A 1 605  ? 159.688 143.456 153.207 1.00 1.03   ? 605  CYS A CA  1 
ATOM 3494 C C   . CYS A 1 605  ? 160.290 144.821 153.517 1.00 1.95   ? 605  CYS A C   1 
ATOM 3495 O O   . CYS A 1 605  ? 160.208 145.320 154.643 1.00 3.85   ? 605  CYS A O   1 
ATOM 3496 C CB  . CYS A 1 605  ? 158.675 143.562 152.065 1.00 0.00   ? 605  CYS A CB  1 
ATOM 3497 S SG  . CYS A 1 605  ? 157.494 144.904 152.257 1.00 8.05   ? 605  CYS A SG  1 
ATOM 3498 N N   . LEU A 1 606  ? 160.898 145.423 152.497 1.00 1.91   ? 606  LEU A N   1 
ATOM 3499 C CA  . LEU A 1 606  ? 161.446 146.769 152.584 1.00 1.66   ? 606  LEU A CA  1 
ATOM 3500 C C   . LEU A 1 606  ? 161.105 147.544 151.320 1.00 8.03   ? 606  LEU A C   1 
ATOM 3501 O O   . LEU A 1 606  ? 161.368 147.073 150.209 1.00 9.33   ? 606  LEU A O   1 
ATOM 3502 C CB  . LEU A 1 606  ? 162.964 146.737 152.790 1.00 2.88   ? 606  LEU A CB  1 
ATOM 3503 C CG  . LEU A 1 606  ? 163.702 148.064 152.598 1.00 4.26   ? 606  LEU A CG  1 
ATOM 3504 C CD1 . LEU A 1 606  ? 163.591 148.924 153.839 1.00 4.69   ? 606  LEU A CD1 1 
ATOM 3505 C CD2 . LEU A 1 606  ? 165.158 147.821 152.259 1.00 9.61   ? 606  LEU A CD2 1 
ATOM 3506 N N   . LEU A 1 607  ? 160.515 148.726 151.490 1.00 5.62   ? 607  LEU A N   1 
ATOM 3507 C CA  . LEU A 1 607  ? 160.333 149.692 150.408 1.00 8.73   ? 607  LEU A CA  1 
ATOM 3508 C C   . LEU A 1 607  ? 161.409 150.759 150.553 1.00 18.25  ? 607  LEU A C   1 
ATOM 3509 O O   . LEU A 1 607  ? 161.345 151.603 151.452 1.00 22.58  ? 607  LEU A O   1 
ATOM 3510 C CB  . LEU A 1 607  ? 158.941 150.313 150.427 1.00 10.80  ? 607  LEU A CB  1 
ATOM 3511 C CG  . LEU A 1 607  ? 157.743 149.418 150.142 1.00 12.66  ? 607  LEU A CG  1 
ATOM 3512 C CD1 . LEU A 1 607  ? 156.480 150.206 150.350 1.00 14.08  ? 607  LEU A CD1 1 
ATOM 3513 C CD2 . LEU A 1 607  ? 157.814 148.926 148.717 1.00 15.67  ? 607  LEU A CD2 1 
ATOM 3514 N N   . ALA A 1 608  ? 162.396 150.722 149.659 1.00 13.79  ? 608  ALA A N   1 
ATOM 3515 C CA  . ALA A 1 608  ? 163.497 151.675 149.664 1.00 15.42  ? 608  ALA A CA  1 
ATOM 3516 C C   . ALA A 1 608  ? 163.384 152.696 148.538 1.00 23.73  ? 608  ALA A C   1 
ATOM 3517 O O   . ALA A 1 608  ? 164.400 153.224 148.076 1.00 31.43  ? 608  ALA A O   1 
ATOM 3518 C CB  . ALA A 1 608  ? 164.833 150.939 149.584 1.00 15.59  ? 608  ALA A CB  1 
ATOM 3519 N N   . ASP A 1 609  ? 162.166 152.983 148.087 1.00 22.68  ? 609  ASP A N   1 
ATOM 3520 C CA  . ASP A 1 609  ? 161.966 153.978 147.046 1.00 23.29  ? 609  ASP A CA  1 
ATOM 3521 C C   . ASP A 1 609  ? 162.400 155.357 147.534 1.00 30.41  ? 609  ASP A C   1 
ATOM 3522 O O   . ASP A 1 609  ? 162.466 155.631 148.734 1.00 38.54  ? 609  ASP A O   1 
ATOM 3523 C CB  . ASP A 1 609  ? 160.499 154.023 146.618 1.00 22.21  ? 609  ASP A CB  1 
ATOM 3524 C CG  . ASP A 1 609  ? 160.067 152.778 145.876 1.00 28.63  ? 609  ASP A CG  1 
ATOM 3525 O OD1 . ASP A 1 609  ? 160.924 151.912 145.612 1.00 32.69  ? 609  ASP A OD1 1 
ATOM 3526 O OD2 . ASP A 1 609  ? 158.867 152.666 145.553 1.00 32.14  ? 609  ASP A OD2 1 
ATOM 3527 N N   . ASP A 1 610  ? 162.705 156.232 146.583 1.00 32.47  ? 610  ASP A N   1 
ATOM 3528 C CA  . ASP A 1 610  ? 162.981 157.617 146.928 1.00 33.73  ? 610  ASP A CA  1 
ATOM 3529 C C   . ASP A 1 610  ? 161.687 158.341 147.277 1.00 36.16  ? 610  ASP A C   1 
ATOM 3530 O O   . ASP A 1 610  ? 160.595 157.948 146.856 1.00 35.38  ? 610  ASP A O   1 
ATOM 3531 C CB  . ASP A 1 610  ? 163.682 158.333 145.775 1.00 35.46  ? 610  ASP A CB  1 
ATOM 3532 C CG  . ASP A 1 610  ? 165.048 157.756 145.474 1.00 38.88  ? 610  ASP A CG  1 
ATOM 3533 O OD1 . ASP A 1 610  ? 165.579 157.003 146.317 1.00 38.60  ? 610  ASP A OD1 1 
ATOM 3534 O OD2 . ASP A 1 610  ? 165.595 158.069 144.397 1.00 38.99  ? 610  ASP A OD2 1 
ATOM 3535 N N   . MET A 1 611  ? 161.814 159.401 148.068 1.00 40.24  ? 611  MET A N   1 
ATOM 3536 C CA  . MET A 1 611  ? 160.658 160.226 148.380 1.00 41.59  ? 611  MET A CA  1 
ATOM 3537 C C   . MET A 1 611  ? 160.176 160.954 147.132 1.00 40.07  ? 611  MET A C   1 
ATOM 3538 O O   . MET A 1 611  ? 160.961 161.309 146.248 1.00 41.69  ? 611  MET A O   1 
ATOM 3539 C CB  . MET A 1 611  ? 160.993 161.225 149.487 1.00 40.32  ? 611  MET A CB  1 
ATOM 3540 C CG  . MET A 1 611  ? 161.035 160.610 150.878 1.00 42.71  ? 611  MET A CG  1 
ATOM 3541 S SD  . MET A 1 611  ? 162.489 159.582 151.161 1.00 53.43  ? 611  MET A SD  1 
ATOM 3542 C CE  . MET A 1 611  ? 163.757 160.834 151.336 1.00 45.52  ? 611  MET A CE  1 
ATOM 3543 N N   . GLY A 1 612  ? 158.866 161.169 147.062 1.00 30.02  ? 612  GLY A N   1 
ATOM 3544 C CA  . GLY A 1 612  ? 158.239 161.757 145.901 1.00 29.26  ? 612  GLY A CA  1 
ATOM 3545 C C   . GLY A 1 612  ? 157.624 160.759 144.944 1.00 29.41  ? 612  GLY A C   1 
ATOM 3546 O O   . GLY A 1 612  ? 156.878 161.168 144.046 1.00 34.48  ? 612  GLY A O   1 
ATOM 3547 N N   . LEU A 1 613  ? 157.917 159.469 145.101 1.00 34.42  ? 613  LEU A N   1 
ATOM 3548 C CA  . LEU A 1 613  ? 157.277 158.439 144.295 1.00 30.85  ? 613  LEU A CA  1 
ATOM 3549 C C   . LEU A 1 613  ? 155.924 158.016 144.846 1.00 28.28  ? 613  LEU A C   1 
ATOM 3550 O O   . LEU A 1 613  ? 155.199 157.280 144.168 1.00 26.81  ? 613  LEU A O   1 
ATOM 3551 C CB  . LEU A 1 613  ? 158.184 157.211 144.178 1.00 30.88  ? 613  LEU A CB  1 
ATOM 3552 C CG  . LEU A 1 613  ? 159.300 157.242 143.131 1.00 29.84  ? 613  LEU A CG  1 
ATOM 3553 C CD1 . LEU A 1 613  ? 160.479 158.086 143.590 1.00 29.42  ? 613  LEU A CD1 1 
ATOM 3554 C CD2 . LEU A 1 613  ? 159.742 155.828 142.799 1.00 29.46  ? 613  LEU A CD2 1 
ATOM 3555 N N   . GLY A 1 614  ? 155.569 158.454 146.050 1.00 30.45  ? 614  GLY A N   1 
ATOM 3556 C CA  . GLY A 1 614  ? 154.274 158.140 146.614 1.00 28.69  ? 614  GLY A CA  1 
ATOM 3557 C C   . GLY A 1 614  ? 154.214 156.800 147.316 1.00 25.40  ? 614  GLY A C   1 
ATOM 3558 O O   . GLY A 1 614  ? 153.371 155.963 146.982 1.00 21.30  ? 614  GLY A O   1 
ATOM 3559 N N   . LYS A 1 615  ? 155.105 156.583 148.289 1.00 26.22  ? 615  LYS A N   1 
ATOM 3560 C CA  . LYS A 1 615  ? 155.029 155.372 149.101 1.00 26.37  ? 615  LYS A CA  1 
ATOM 3561 C C   . LYS A 1 615  ? 153.694 155.280 149.823 1.00 26.48  ? 615  LYS A C   1 
ATOM 3562 O O   . LYS A 1 615  ? 153.148 154.185 150.002 1.00 25.81  ? 615  LYS A O   1 
ATOM 3563 C CB  . LYS A 1 615  ? 156.160 155.338 150.128 1.00 24.72  ? 615  LYS A CB  1 
ATOM 3564 C CG  . LYS A 1 615  ? 157.559 155.218 149.571 1.00 30.08  ? 615  LYS A CG  1 
ATOM 3565 C CD  . LYS A 1 615  ? 158.554 155.182 150.721 1.00 26.81  ? 615  LYS A CD  1 
ATOM 3566 C CE  . LYS A 1 615  ? 159.967 154.973 150.241 1.00 23.55  ? 615  LYS A CE  1 
ATOM 3567 N NZ  . LYS A 1 615  ? 160.442 156.146 149.461 1.00 25.54  ? 615  LYS A NZ  1 
ATOM 3568 N N   . THR A 1 616  ? 153.167 156.425 150.262 1.00 22.31  ? 616  THR A N   1 
ATOM 3569 C CA  . THR A 1 616  ? 151.959 156.430 151.077 1.00 16.32  ? 616  THR A CA  1 
ATOM 3570 C C   . THR A 1 616  ? 150.781 155.829 150.324 1.00 14.33  ? 616  THR A C   1 
ATOM 3571 O O   . THR A 1 616  ? 150.032 155.018 150.878 1.00 21.69  ? 616  THR A O   1 
ATOM 3572 C CB  . THR A 1 616  ? 151.646 157.858 151.526 1.00 14.97  ? 616  THR A CB  1 
ATOM 3573 O OG1 . THR A 1 616  ? 152.681 158.320 152.403 1.00 21.86  ? 616  THR A OG1 1 
ATOM 3574 C CG2 . THR A 1 616  ? 150.322 157.916 152.258 1.00 16.40  ? 616  THR A CG2 1 
ATOM 3575 N N   . LEU A 1 617  ? 150.616 156.193 149.051 1.00 19.16  ? 617  LEU A N   1 
ATOM 3576 C CA  . LEU A 1 617  ? 149.475 155.695 148.291 1.00 19.59  ? 617  LEU A CA  1 
ATOM 3577 C C   . LEU A 1 617  ? 149.597 154.198 148.023 1.00 16.81  ? 617  LEU A C   1 
ATOM 3578 O O   . LEU A 1 617  ? 148.602 153.472 148.102 1.00 16.75  ? 617  LEU A O   1 
ATOM 3579 C CB  . LEU A 1 617  ? 149.330 156.482 146.987 1.00 22.65  ? 617  LEU A CB  1 
ATOM 3580 C CG  . LEU A 1 617  ? 148.314 155.994 145.950 1.00 25.93  ? 617  LEU A CG  1 
ATOM 3581 C CD1 . LEU A 1 617  ? 146.990 155.607 146.593 1.00 22.59  ? 617  LEU A CD1 1 
ATOM 3582 C CD2 . LEU A 1 617  ? 148.087 157.051 144.882 1.00 23.08  ? 617  LEU A CD2 1 
ATOM 3583 N N   . GLN A 1 618  ? 150.802 153.710 147.718 1.00 17.45  ? 618  GLN A N   1 
ATOM 3584 C CA  . GLN A 1 618  ? 150.976 152.276 147.496 1.00 17.42  ? 618  GLN A CA  1 
ATOM 3585 C C   . GLN A 1 618  ? 150.727 151.484 148.775 1.00 17.54  ? 618  GLN A C   1 
ATOM 3586 O O   . GLN A 1 618  ? 150.031 150.458 148.761 1.00 20.00  ? 618  GLN A O   1 
ATOM 3587 C CB  . GLN A 1 618  ? 152.374 151.982 146.949 1.00 16.44  ? 618  GLN A CB  1 
ATOM 3588 C CG  . GLN A 1 618  ? 152.921 153.023 145.992 1.00 20.67  ? 618  GLN A CG  1 
ATOM 3589 C CD  . GLN A 1 618  ? 154.362 152.751 145.604 1.00 20.46  ? 618  GLN A CD  1 
ATOM 3590 O OE1 . GLN A 1 618  ? 154.742 151.609 145.351 1.00 17.70  ? 618  GLN A OE1 1 
ATOM 3591 N NE2 . GLN A 1 618  ? 155.173 153.801 145.558 1.00 20.70  ? 618  GLN A NE2 1 
ATOM 3592 N N   . ILE A 1 619  ? 151.287 151.948 149.896 1.00 14.67  ? 619  ILE A N   1 
ATOM 3593 C CA  . ILE A 1 619  ? 151.068 151.263 151.166 1.00 7.46   ? 619  ILE A CA  1 
ATOM 3594 C C   . ILE A 1 619  ? 149.590 151.263 151.522 1.00 8.09   ? 619  ILE A C   1 
ATOM 3595 O O   . ILE A 1 619  ? 149.045 150.242 151.956 1.00 16.46  ? 619  ILE A O   1 
ATOM 3596 C CB  . ILE A 1 619  ? 151.912 151.896 152.285 1.00 10.66  ? 619  ILE A CB  1 
ATOM 3597 C CG1 . ILE A 1 619  ? 153.378 151.508 152.133 1.00 9.37   ? 619  ILE A CG1 1 
ATOM 3598 C CG2 . ILE A 1 619  ? 151.423 151.418 153.640 1.00 11.80  ? 619  ILE A CG2 1 
ATOM 3599 C CD1 . ILE A 1 619  ? 153.599 150.027 152.268 1.00 9.82   ? 619  ILE A CD1 1 
ATOM 3600 N N   . LEU A 1 620  ? 148.913 152.399 151.347 1.00 6.30   ? 620  LEU A N   1 
ATOM 3601 C CA  . LEU A 1 620  ? 147.503 152.463 151.703 1.00 6.69   ? 620  LEU A CA  1 
ATOM 3602 C C   . LEU A 1 620  ? 146.661 151.601 150.775 1.00 7.54   ? 620  LEU A C   1 
ATOM 3603 O O   . LEU A 1 620  ? 145.709 150.965 151.222 1.00 16.92  ? 620  LEU A O   1 
ATOM 3604 C CB  . LEU A 1 620  ? 147.017 153.909 151.692 1.00 10.07  ? 620  LEU A CB  1 
ATOM 3605 C CG  . LEU A 1 620  ? 147.333 154.674 152.978 1.00 16.91  ? 620  LEU A CG  1 
ATOM 3606 C CD1 . LEU A 1 620  ? 147.251 156.172 152.747 1.00 16.92  ? 620  LEU A CD1 1 
ATOM 3607 C CD2 . LEU A 1 620  ? 146.433 154.240 154.124 1.00 14.16  ? 620  LEU A CD2 1 
ATOM 3608 N N   . SER A 1 621  ? 146.997 151.554 149.486 1.00 9.81   ? 621  SER A N   1 
ATOM 3609 C CA  . SER A 1 621  ? 146.275 150.672 148.577 1.00 13.11  ? 621  SER A CA  1 
ATOM 3610 C C   . SER A 1 621  ? 146.427 149.218 148.999 1.00 15.40  ? 621  SER A C   1 
ATOM 3611 O O   . SER A 1 621  ? 145.450 148.462 149.017 1.00 14.89  ? 621  SER A O   1 
ATOM 3612 C CB  . SER A 1 621  ? 146.772 150.873 147.146 1.00 12.32  ? 621  SER A CB  1 
ATOM 3613 O OG  . SER A 1 621  ? 146.494 152.183 146.687 1.00 16.30  ? 621  SER A OG  1 
ATOM 3614 N N   . PHE A 1 622  ? 147.646 148.819 149.367 1.00 11.49  ? 622  PHE A N   1 
ATOM 3615 C CA  . PHE A 1 622  ? 147.882 147.452 149.819 1.00 5.47   ? 622  PHE A CA  1 
ATOM 3616 C C   . PHE A 1 622  ? 147.111 147.153 151.105 1.00 10.25  ? 622  PHE A C   1 
ATOM 3617 O O   . PHE A 1 622  ? 146.471 146.097 151.228 1.00 14.73  ? 622  PHE A O   1 
ATOM 3618 C CB  . PHE A 1 622  ? 149.390 147.248 149.990 1.00 5.50   ? 622  PHE A CB  1 
ATOM 3619 C CG  . PHE A 1 622  ? 149.773 146.033 150.780 1.00 10.57  ? 622  PHE A CG  1 
ATOM 3620 C CD1 . PHE A 1 622  ? 149.357 144.772 150.392 1.00 3.38   ? 622  PHE A CD1 1 
ATOM 3621 C CD2 . PHE A 1 622  ? 150.592 146.152 151.889 1.00 0.94   ? 622  PHE A CD2 1 
ATOM 3622 C CE1 . PHE A 1 622  ? 149.726 143.658 151.113 1.00 2.96   ? 622  PHE A CE1 1 
ATOM 3623 C CE2 . PHE A 1 622  ? 150.965 145.043 152.611 1.00 6.97   ? 622  PHE A CE2 1 
ATOM 3624 C CZ  . PHE A 1 622  ? 150.532 143.794 152.223 1.00 8.28   ? 622  PHE A CZ  1 
ATOM 3625 N N   . LEU A 1 623  ? 147.121 148.093 152.055 1.00 7.16   ? 623  LEU A N   1 
ATOM 3626 C CA  . LEU A 1 623  ? 146.403 147.897 153.312 1.00 2.60   ? 623  LEU A CA  1 
ATOM 3627 C C   . LEU A 1 623  ? 144.899 147.799 153.095 1.00 12.00  ? 623  LEU A C   1 
ATOM 3628 O O   . LEU A 1 623  ? 144.243 146.927 153.671 1.00 21.09  ? 623  LEU A O   1 
ATOM 3629 C CB  . LEU A 1 623  ? 146.714 149.031 154.287 1.00 0.94   ? 623  LEU A CB  1 
ATOM 3630 C CG  . LEU A 1 623  ? 148.154 149.193 154.764 1.00 1.22   ? 623  LEU A CG  1 
ATOM 3631 C CD1 . LEU A 1 623  ? 148.296 150.461 155.580 1.00 6.42   ? 623  LEU A CD1 1 
ATOM 3632 C CD2 . LEU A 1 623  ? 148.564 147.987 155.576 1.00 13.79  ? 623  LEU A CD2 1 
ATOM 3633 N N   . VAL A 1 624  ? 144.329 148.690 152.282 1.00 9.09   ? 624  VAL A N   1 
ATOM 3634 C CA  . VAL A 1 624  ? 142.887 148.673 152.056 1.00 7.95   ? 624  VAL A CA  1 
ATOM 3635 C C   . VAL A 1 624  ? 142.475 147.434 151.270 1.00 13.23  ? 624  VAL A C   1 
ATOM 3636 O O   . VAL A 1 624  ? 141.399 146.865 151.502 1.00 13.72  ? 624  VAL A O   1 
ATOM 3637 C CB  . VAL A 1 624  ? 142.436 149.974 151.369 1.00 7.90   ? 624  VAL A CB  1 
ATOM 3638 C CG1 . VAL A 1 624  ? 140.949 150.083 151.412 1.00 17.63  ? 624  VAL A CG1 1 
ATOM 3639 C CG2 . VAL A 1 624  ? 143.009 151.171 152.091 1.00 9.67   ? 624  VAL A CG2 1 
ATOM 3640 N N   . TRP A 1 625  ? 143.316 146.991 150.330 1.00 9.11   ? 625  TRP A N   1 
ATOM 3641 C CA  . TRP A 1 625  ? 143.046 145.731 149.648 1.00 10.61  ? 625  TRP A CA  1 
ATOM 3642 C C   . TRP A 1 625  ? 143.006 144.576 150.638 1.00 14.22  ? 625  TRP A C   1 
ATOM 3643 O O   . TRP A 1 625  ? 142.108 143.726 150.577 1.00 14.08  ? 625  TRP A O   1 
ATOM 3644 C CB  . TRP A 1 625  ? 144.100 145.476 148.572 1.00 12.24  ? 625  TRP A CB  1 
ATOM 3645 C CG  . TRP A 1 625  ? 144.185 144.041 148.160 1.00 10.98  ? 625  TRP A CG  1 
ATOM 3646 C CD1 . TRP A 1 625  ? 143.380 143.395 147.270 1.00 11.74  ? 625  TRP A CD1 1 
ATOM 3647 C CD2 . TRP A 1 625  ? 145.125 143.068 148.630 1.00 12.04  ? 625  TRP A CD2 1 
ATOM 3648 N NE1 . TRP A 1 625  ? 143.762 142.081 147.153 1.00 20.43  ? 625  TRP A NE1 1 
ATOM 3649 C CE2 . TRP A 1 625  ? 144.832 141.856 147.978 1.00 17.79  ? 625  TRP A CE2 1 
ATOM 3650 C CE3 . TRP A 1 625  ? 146.189 143.106 149.536 1.00 6.58   ? 625  TRP A CE3 1 
ATOM 3651 C CZ2 . TRP A 1 625  ? 145.563 140.693 148.205 1.00 14.49  ? 625  TRP A CZ2 1 
ATOM 3652 C CZ3 . TRP A 1 625  ? 146.911 141.952 149.760 1.00 7.51   ? 625  TRP A CZ3 1 
ATOM 3653 C CH2 . TRP A 1 625  ? 146.595 140.762 149.098 1.00 11.51  ? 625  TRP A CH2 1 
ATOM 3654 N N   . PHE A 1 626  ? 143.965 144.535 151.568 1.00 14.53  ? 626  PHE A N   1 
ATOM 3655 C CA  . PHE A 1 626  ? 143.928 143.507 152.603 1.00 10.57  ? 626  PHE A CA  1 
ATOM 3656 C C   . PHE A 1 626  ? 142.668 143.615 153.453 1.00 16.50  ? 626  PHE A C   1 
ATOM 3657 O O   . PHE A 1 626  ? 142.042 142.601 153.781 1.00 16.49  ? 626  PHE A O   1 
ATOM 3658 C CB  . PHE A 1 626  ? 145.165 143.594 153.492 1.00 3.81   ? 626  PHE A CB  1 
ATOM 3659 C CG  . PHE A 1 626  ? 145.121 142.654 154.656 1.00 11.26  ? 626  PHE A CG  1 
ATOM 3660 C CD1 . PHE A 1 626  ? 145.402 141.318 154.485 1.00 16.20  ? 626  PHE A CD1 1 
ATOM 3661 C CD2 . PHE A 1 626  ? 144.770 143.101 155.915 1.00 13.63  ? 626  PHE A CD2 1 
ATOM 3662 C CE1 . PHE A 1 626  ? 145.348 140.440 155.547 1.00 15.78  ? 626  PHE A CE1 1 
ATOM 3663 C CE2 . PHE A 1 626  ? 144.713 142.231 156.978 1.00 12.18  ? 626  PHE A CE2 1 
ATOM 3664 C CZ  . PHE A 1 626  ? 145.008 140.898 156.794 1.00 13.60  ? 626  PHE A CZ  1 
ATOM 3665 N N   . ILE A 1 627  ? 142.291 144.838 153.830 1.00 17.97  ? 627  ILE A N   1 
ATOM 3666 C CA  . ILE A 1 627  ? 141.150 145.030 154.722 1.00 10.48  ? 627  ILE A CA  1 
ATOM 3667 C C   . ILE A 1 627  ? 139.865 144.543 154.067 1.00 17.64  ? 627  ILE A C   1 
ATOM 3668 O O   . ILE A 1 627  ? 139.054 143.857 154.700 1.00 21.12  ? 627  ILE A O   1 
ATOM 3669 C CB  . ILE A 1 627  ? 141.049 146.505 155.153 1.00 6.86   ? 627  ILE A CB  1 
ATOM 3670 C CG1 . ILE A 1 627  ? 142.271 146.903 155.979 1.00 6.91   ? 627  ILE A CG1 1 
ATOM 3671 C CG2 . ILE A 1 627  ? 139.778 146.742 155.950 1.00 12.26  ? 627  ILE A CG2 1 
ATOM 3672 C CD1 . ILE A 1 627  ? 142.272 148.348 156.406 1.00 10.91  ? 627  ILE A CD1 1 
ATOM 3673 N N   . GLU A 1 628  ? 139.652 144.884 152.792 1.00 19.69  ? 628  GLU A N   1 
ATOM 3674 C CA  . GLU A 1 628  ? 138.454 144.390 152.117 1.00 16.10  ? 628  GLU A CA  1 
ATOM 3675 C C   . GLU A 1 628  ? 138.516 142.885 151.891 1.00 17.54  ? 628  GLU A C   1 
ATOM 3676 O O   . GLU A 1 628  ? 137.539 142.175 152.153 1.00 20.58  ? 628  GLU A O   1 
ATOM 3677 C CB  . GLU A 1 628  ? 138.225 145.097 150.783 1.00 19.18  ? 628  GLU A CB  1 
ATOM 3678 C CG  . GLU A 1 628  ? 138.060 146.598 150.836 1.00 19.17  ? 628  GLU A CG  1 
ATOM 3679 C CD  . GLU A 1 628  ? 138.827 147.290 149.733 1.00 27.20  ? 628  GLU A CD  1 
ATOM 3680 O OE1 . GLU A 1 628  ? 139.268 146.596 148.793 1.00 28.30  ? 628  GLU A OE1 1 
ATOM 3681 O OE2 . GLU A 1 628  ? 138.943 148.529 149.774 1.00 27.47  ? 628  GLU A OE2 1 
ATOM 3682 N N   . LYS A 1 629  ? 139.646 142.376 151.395 1.00 18.39  ? 629  LYS A N   1 
ATOM 3683 C CA  . LYS A 1 629  ? 139.689 140.973 150.999 1.00 20.29  ? 629  LYS A CA  1 
ATOM 3684 C C   . LYS A 1 629  ? 139.732 140.041 152.204 1.00 20.27  ? 629  LYS A C   1 
ATOM 3685 O O   . LYS A 1 629  ? 139.269 138.898 152.116 1.00 21.91  ? 629  LYS A O   1 
ATOM 3686 C CB  . LYS A 1 629  ? 140.887 140.724 150.078 1.00 17.52  ? 629  LYS A CB  1 
ATOM 3687 C CG  . LYS A 1 629  ? 140.975 139.307 149.528 1.00 16.66  ? 629  LYS A CG  1 
ATOM 3688 C CD  . LYS A 1 629  ? 142.152 139.148 148.582 1.00 21.49  ? 629  LYS A CD  1 
ATOM 3689 C CE  . LYS A 1 629  ? 142.185 137.759 147.959 1.00 23.16  ? 629  LYS A CE  1 
ATOM 3690 N NZ  . LYS A 1 629  ? 142.477 136.681 148.943 1.00 21.97  ? 629  LYS A NZ  1 
ATOM 3691 N N   . PHE A 1 630  ? 140.260 140.512 153.331 1.00 21.23  ? 630  PHE A N   1 
ATOM 3692 C CA  . PHE A 1 630  ? 140.358 139.728 154.562 1.00 19.13  ? 630  PHE A CA  1 
ATOM 3693 C C   . PHE A 1 630  ? 139.770 140.547 155.703 1.00 21.57  ? 630  PHE A C   1 
ATOM 3694 O O   . PHE A 1 630  ? 140.506 141.164 156.486 1.00 24.45  ? 630  PHE A O   1 
ATOM 3695 C CB  . PHE A 1 630  ? 141.807 139.337 154.850 1.00 14.21  ? 630  PHE A CB  1 
ATOM 3696 C CG  . PHE A 1 630  ? 142.521 138.723 153.680 1.00 17.03  ? 630  PHE A CG  1 
ATOM 3697 C CD1 . PHE A 1 630  ? 143.270 139.507 152.820 1.00 19.79  ? 630  PHE A CD1 1 
ATOM 3698 C CD2 . PHE A 1 630  ? 142.461 137.361 153.453 1.00 16.43  ? 630  PHE A CD2 1 
ATOM 3699 C CE1 . PHE A 1 630  ? 143.935 138.948 151.751 1.00 19.77  ? 630  PHE A CE1 1 
ATOM 3700 C CE2 . PHE A 1 630  ? 143.124 136.795 152.383 1.00 20.42  ? 630  PHE A CE2 1 
ATOM 3701 C CZ  . PHE A 1 630  ? 143.864 137.591 151.533 1.00 22.37  ? 630  PHE A CZ  1 
ATOM 3702 N N   . PRO A 1 631  ? 138.440 140.572 155.834 1.00 20.40  ? 631  PRO A N   1 
ATOM 3703 C CA  . PRO A 1 631  ? 137.810 141.452 156.829 1.00 20.47  ? 631  PRO A CA  1 
ATOM 3704 C C   . PRO A 1 631  ? 137.791 140.901 158.246 1.00 28.24  ? 631  PRO A C   1 
ATOM 3705 O O   . PRO A 1 631  ? 137.400 141.634 159.164 1.00 28.16  ? 631  PRO A O   1 
ATOM 3706 C CB  . PRO A 1 631  ? 136.378 141.621 156.294 1.00 20.24  ? 631  PRO A CB  1 
ATOM 3707 C CG  . PRO A 1 631  ? 136.212 140.604 155.185 1.00 23.67  ? 631  PRO A CG  1 
ATOM 3708 C CD  . PRO A 1 631  ? 137.453 139.778 155.089 1.00 21.38  ? 631  PRO A CD  1 
ATOM 3709 N N   . GLN A 1 632  ? 138.188 139.648 158.459 1.00 27.23  ? 632  GLN A N   1 
ATOM 3710 C CA  . GLN A 1 632  ? 138.150 139.037 159.781 1.00 27.79  ? 632  GLN A CA  1 
ATOM 3711 C C   . GLN A 1 632  ? 139.519 138.966 160.447 1.00 31.66  ? 632  GLN A C   1 
ATOM 3712 O O   . GLN A 1 632  ? 139.628 138.421 161.550 1.00 31.91  ? 632  GLN A O   1 
ATOM 3713 C CB  . GLN A 1 632  ? 137.548 137.632 159.691 1.00 25.67  ? 632  GLN A CB  1 
ATOM 3714 C CG  . GLN A 1 632  ? 136.088 137.605 159.265 1.00 28.10  ? 632  GLN A CG  1 
ATOM 3715 C CD  . GLN A 1 632  ? 135.178 138.312 160.250 1.00 33.73  ? 632  GLN A CD  1 
ATOM 3716 O OE1 . GLN A 1 632  ? 134.651 139.387 159.964 1.00 35.24  ? 632  GLN A OE1 1 
ATOM 3717 N NE2 . GLN A 1 632  ? 134.985 137.707 161.416 1.00 31.62  ? 632  GLN A NE2 1 
ATOM 3718 N N   . GLU A 1 633  ? 140.554 139.500 159.812 1.00 19.93  ? 633  GLU A N   1 
ATOM 3719 C CA  . GLU A 1 633  ? 141.912 139.412 160.321 1.00 12.96  ? 633  GLU A CA  1 
ATOM 3720 C C   . GLU A 1 633  ? 142.199 140.527 161.324 1.00 14.58  ? 633  GLU A C   1 
ATOM 3721 O O   . GLU A 1 633  ? 141.484 141.531 161.371 1.00 17.10  ? 633  GLU A O   1 
ATOM 3722 C CB  . GLU A 1 633  ? 142.898 139.466 159.160 1.00 15.45  ? 633  GLU A CB  1 
ATOM 3723 C CG  . GLU A 1 633  ? 142.610 138.451 158.078 1.00 20.48  ? 633  GLU A CG  1 
ATOM 3724 C CD  . GLU A 1 633  ? 143.165 137.080 158.401 1.00 23.06  ? 633  GLU A CD  1 
ATOM 3725 O OE1 . GLU A 1 633  ? 142.473 136.078 158.126 1.00 23.97  ? 633  GLU A OE1 1 
ATOM 3726 O OE2 . GLU A 1 633  ? 144.293 137.004 158.928 1.00 26.68  ? 633  GLU A OE2 1 
ATOM 3727 N N   . PRO A 1 634  ? 143.240 140.373 162.144 1.00 10.14  ? 634  PRO A N   1 
ATOM 3728 C CA  . PRO A 1 634  ? 143.577 141.418 163.121 1.00 4.95   ? 634  PRO A CA  1 
ATOM 3729 C C   . PRO A 1 634  ? 143.968 142.711 162.430 1.00 5.00   ? 634  PRO A C   1 
ATOM 3730 O O   . PRO A 1 634  ? 144.402 142.703 161.269 1.00 10.04  ? 634  PRO A O   1 
ATOM 3731 C CB  . PRO A 1 634  ? 144.758 140.819 163.901 1.00 7.86   ? 634  PRO A CB  1 
ATOM 3732 C CG  . PRO A 1 634  ? 145.267 139.703 163.079 1.00 7.40   ? 634  PRO A CG  1 
ATOM 3733 C CD  . PRO A 1 634  ? 144.133 139.207 162.249 1.00 7.26   ? 634  PRO A CD  1 
ATOM 3734 N N   . PRO A 1 635  ? 143.809 143.851 163.110 1.00 5.28   ? 635  PRO A N   1 
ATOM 3735 C CA  . PRO A 1 635  ? 144.054 145.151 162.464 1.00 6.10   ? 635  PRO A CA  1 
ATOM 3736 C C   . PRO A 1 635  ? 145.489 145.361 162.008 1.00 6.80   ? 635  PRO A C   1 
ATOM 3737 O O   . PRO A 1 635  ? 146.365 144.522 162.240 1.00 9.09   ? 635  PRO A O   1 
ATOM 3738 C CB  . PRO A 1 635  ? 143.683 146.171 163.549 1.00 3.98   ? 635  PRO A CB  1 
ATOM 3739 C CG  . PRO A 1 635  ? 143.106 145.422 164.679 1.00 9.15   ? 635  PRO A CG  1 
ATOM 3740 C CD  . PRO A 1 635  ? 143.103 143.966 164.396 1.00 9.47   ? 635  PRO A CD  1 
ATOM 3741 N N   . ASN A 1 636  ? 145.732 146.497 161.361 1.00 4.56   ? 636  ASN A N   1 
ATOM 3742 C CA  . ASN A 1 636  ? 147.040 146.865 160.845 1.00 0.24   ? 636  ASN A CA  1 
ATOM 3743 C C   . ASN A 1 636  ? 147.605 148.031 161.644 1.00 0.86   ? 636  ASN A C   1 
ATOM 3744 O O   . ASN A 1 636  ? 146.861 148.814 162.240 1.00 12.02  ? 636  ASN A O   1 
ATOM 3745 C CB  . ASN A 1 636  ? 146.960 147.242 159.363 1.00 0.00   ? 636  ASN A CB  1 
ATOM 3746 C CG  . ASN A 1 636  ? 146.229 146.205 158.539 1.00 2.34   ? 636  ASN A CG  1 
ATOM 3747 O OD1 . ASN A 1 636  ? 146.746 145.118 158.289 1.00 7.73   ? 636  ASN A OD1 1 
ATOM 3748 N ND2 . ASN A 1 636  ? 145.019 146.537 158.111 1.00 7.70   ? 636  ASN A ND2 1 
ATOM 3749 N N   . LEU A 1 637  ? 148.931 148.140 161.650 1.00 0.00   ? 637  LEU A N   1 
ATOM 3750 C CA  . LEU A 1 637  ? 149.630 149.149 162.432 1.00 0.00   ? 637  LEU A CA  1 
ATOM 3751 C C   . LEU A 1 637  ? 150.575 149.928 161.530 1.00 0.00   ? 637  LEU A C   1 
ATOM 3752 O O   . LEU A 1 637  ? 151.341 149.333 160.768 1.00 13.33  ? 637  LEU A O   1 
ATOM 3753 C CB  . LEU A 1 637  ? 150.407 148.502 163.584 1.00 0.00   ? 637  LEU A CB  1 
ATOM 3754 C CG  . LEU A 1 637  ? 151.122 149.422 164.574 1.00 0.08   ? 637  LEU A CG  1 
ATOM 3755 C CD1 . LEU A 1 637  ? 150.113 150.200 165.400 1.00 5.16   ? 637  LEU A CD1 1 
ATOM 3756 C CD2 . LEU A 1 637  ? 152.048 148.618 165.469 1.00 1.28   ? 637  LEU A CD2 1 
ATOM 3757 N N   . ILE A 1 638  ? 150.517 151.255 161.615 1.00 0.00   ? 638  ILE A N   1 
ATOM 3758 C CA  . ILE A 1 638  ? 151.454 152.137 160.929 1.00 2.34   ? 638  ILE A CA  1 
ATOM 3759 C C   . ILE A 1 638  ? 152.173 152.960 161.986 1.00 5.14   ? 638  ILE A C   1 
ATOM 3760 O O   . ILE A 1 638  ? 151.528 153.610 162.818 1.00 11.42  ? 638  ILE A O   1 
ATOM 3761 C CB  . ILE A 1 638  ? 150.757 153.047 159.906 1.00 4.33   ? 638  ILE A CB  1 
ATOM 3762 C CG1 . ILE A 1 638  ? 149.930 152.221 158.923 1.00 5.16   ? 638  ILE A CG1 1 
ATOM 3763 C CG2 . ILE A 1 638  ? 151.779 153.889 159.159 1.00 2.12   ? 638  ILE A CG2 1 
ATOM 3764 C CD1 . ILE A 1 638  ? 149.004 153.052 158.072 1.00 5.83   ? 638  ILE A CD1 1 
ATOM 3765 N N   . VAL A 1 639  ? 153.501 152.935 161.954 1.00 0.00   ? 639  VAL A N   1 
ATOM 3766 C CA  . VAL A 1 639  ? 154.333 153.636 162.924 1.00 0.00   ? 639  VAL A CA  1 
ATOM 3767 C C   . VAL A 1 639  ? 155.124 154.696 162.173 1.00 5.01   ? 639  VAL A C   1 
ATOM 3768 O O   . VAL A 1 639  ? 155.870 154.373 161.240 1.00 13.93  ? 639  VAL A O   1 
ATOM 3769 C CB  . VAL A 1 639  ? 155.274 152.676 163.667 1.00 0.00   ? 639  VAL A CB  1 
ATOM 3770 C CG1 . VAL A 1 639  ? 156.191 153.446 164.592 1.00 0.96   ? 639  VAL A CG1 1 
ATOM 3771 C CG2 . VAL A 1 639  ? 154.483 151.629 164.430 1.00 2.49   ? 639  VAL A CG2 1 
ATOM 3772 N N   . ALA A 1 640  ? 154.966 155.953 162.576 1.00 2.13   ? 640  ALA A N   1 
ATOM 3773 C CA  . ALA A 1 640  ? 155.649 157.057 161.902 1.00 9.11   ? 640  ALA A CA  1 
ATOM 3774 C C   . ALA A 1 640  ? 155.685 158.245 162.857 1.00 13.12  ? 640  ALA A C   1 
ATOM 3775 O O   . ALA A 1 640  ? 154.925 158.289 163.834 1.00 19.44  ? 640  ALA A O   1 
ATOM 3776 C CB  . ALA A 1 640  ? 154.945 157.431 160.591 1.00 16.12  ? 640  ALA A CB  1 
ATOM 3777 N N   . PRO A 1 641  ? 156.586 159.205 162.620 1.00 11.69  ? 641  PRO A N   1 
ATOM 3778 C CA  . PRO A 1 641  ? 156.509 160.479 163.345 1.00 15.97  ? 641  PRO A CA  1 
ATOM 3779 C C   . PRO A 1 641  ? 155.119 161.111 163.281 1.00 19.11  ? 641  PRO A C   1 
ATOM 3780 O O   . PRO A 1 641  ? 154.271 160.774 162.450 1.00 18.25  ? 641  PRO A O   1 
ATOM 3781 C CB  . PRO A 1 641  ? 157.540 161.337 162.622 1.00 16.35  ? 641  PRO A CB  1 
ATOM 3782 C CG  . PRO A 1 641  ? 158.627 160.349 162.226 1.00 13.28  ? 641  PRO A CG  1 
ATOM 3783 C CD  . PRO A 1 641  ? 157.969 158.957 162.206 1.00 10.71  ? 641  PRO A CD  1 
ATOM 3784 N N   . VAL A 1 642  ? 154.897 162.073 164.185 1.00 21.08  ? 642  VAL A N   1 
ATOM 3785 C CA  . VAL A 1 642  ? 153.560 162.629 164.392 1.00 24.63  ? 642  VAL A CA  1 
ATOM 3786 C C   . VAL A 1 642  ? 153.077 163.366 163.147 1.00 25.14  ? 642  VAL A C   1 
ATOM 3787 O O   . VAL A 1 642  ? 151.955 163.148 162.669 1.00 23.77  ? 642  VAL A O   1 
ATOM 3788 C CB  . VAL A 1 642  ? 153.552 163.552 165.622 1.00 22.29  ? 642  VAL A CB  1 
ATOM 3789 C CG1 . VAL A 1 642  ? 152.193 164.213 165.777 1.00 21.31  ? 642  VAL A CG1 1 
ATOM 3790 C CG2 . VAL A 1 642  ? 153.931 162.772 166.869 1.00 21.18  ? 642  VAL A CG2 1 
ATOM 3791 N N   . SER A 1 643  ? 153.907 164.267 162.617 1.00 26.94  ? 643  SER A N   1 
ATOM 3792 C CA  . SER A 1 643  ? 153.512 165.024 161.434 1.00 27.28  ? 643  SER A CA  1 
ATOM 3793 C C   . SER A 1 643  ? 153.269 164.096 160.253 1.00 24.14  ? 643  SER A C   1 
ATOM 3794 O O   . SER A 1 643  ? 152.293 164.257 159.510 1.00 26.60  ? 643  SER A O   1 
ATOM 3795 C CB  . SER A 1 643  ? 154.581 166.064 161.096 1.00 29.16  ? 643  SER A CB  1 
ATOM 3796 O OG  . SER A 1 643  ? 155.791 165.441 160.705 1.00 19.97  ? 643  SER A OG  1 
ATOM 3797 N N   . LEU A 1 644  ? 154.132 163.097 160.081 1.00 19.26  ? 644  LEU A N   1 
ATOM 3798 C CA  . LEU A 1 644  ? 153.898 162.113 159.035 1.00 19.69  ? 644  LEU A CA  1 
ATOM 3799 C C   . LEU A 1 644  ? 152.674 161.261 159.335 1.00 22.78  ? 644  LEU A C   1 
ATOM 3800 O O   . LEU A 1 644  ? 152.031 160.768 158.408 1.00 26.76  ? 644  LEU A O   1 
ATOM 3801 C CB  . LEU A 1 644  ? 155.128 161.228 158.837 1.00 18.44  ? 644  LEU A CB  1 
ATOM 3802 C CG  . LEU A 1 644  ? 156.390 161.819 158.194 1.00 17.78  ? 644  LEU A CG  1 
ATOM 3803 C CD1 . LEU A 1 644  ? 156.958 163.034 158.917 1.00 20.41  ? 644  LEU A CD1 1 
ATOM 3804 C CD2 . LEU A 1 644  ? 157.437 160.749 158.072 1.00 19.90  ? 644  LEU A CD2 1 
ATOM 3805 N N   . LEU A 1 645  ? 152.328 161.077 160.609 1.00 22.02  ? 645  LEU A N   1 
ATOM 3806 C CA  . LEU A 1 645  ? 151.101 160.354 160.929 1.00 22.93  ? 645  LEU A CA  1 
ATOM 3807 C C   . LEU A 1 645  ? 149.875 161.135 160.471 1.00 24.45  ? 645  LEU A C   1 
ATOM 3808 O O   . LEU A 1 645  ? 148.939 160.562 159.892 1.00 26.21  ? 645  LEU A O   1 
ATOM 3809 C CB  . LEU A 1 645  ? 151.030 160.085 162.428 1.00 20.07  ? 645  LEU A CB  1 
ATOM 3810 C CG  . LEU A 1 645  ? 151.446 158.693 162.889 1.00 21.27  ? 645  LEU A CG  1 
ATOM 3811 C CD1 . LEU A 1 645  ? 151.371 158.643 164.400 1.00 18.62  ? 645  LEU A CD1 1 
ATOM 3812 C CD2 . LEU A 1 645  ? 150.615 157.609 162.240 1.00 21.63  ? 645  LEU A CD2 1 
ATOM 3813 N N   . ASP A 1 646  ? 149.866 162.445 160.728 1.00 28.66  ? 646  ASP A N   1 
ATOM 3814 C CA  . ASP A 1 646  ? 148.819 163.301 160.181 1.00 27.65  ? 646  ASP A CA  1 
ATOM 3815 C C   . ASP A 1 646  ? 148.815 163.241 158.661 1.00 29.68  ? 646  ASP A C   1 
ATOM 3816 O O   . ASP A 1 646  ? 147.751 163.263 158.031 1.00 32.85  ? 646  ASP A O   1 
ATOM 3817 C CB  . ASP A 1 646  ? 149.014 164.740 160.659 1.00 27.36  ? 646  ASP A CB  1 
ATOM 3818 C CG  . ASP A 1 646  ? 148.890 164.877 162.163 1.00 34.42  ? 646  ASP A CG  1 
ATOM 3819 O OD1 . ASP A 1 646  ? 149.740 165.563 162.770 1.00 38.30  ? 646  ASP A OD1 1 
ATOM 3820 O OD2 . ASP A 1 646  ? 147.942 164.303 162.737 1.00 31.47  ? 646  ASP A OD2 1 
ATOM 3821 N N   . ASN A 1 647  ? 150.003 163.165 158.058 1.00 31.24  ? 647  ASN A N   1 
ATOM 3822 C CA  . ASN A 1 647  ? 150.099 163.017 156.609 1.00 26.49  ? 647  ASN A CA  1 
ATOM 3823 C C   . ASN A 1 647  ? 149.420 161.736 156.135 1.00 24.07  ? 647  ASN A C   1 
ATOM 3824 O O   . ASN A 1 647  ? 148.653 161.756 155.167 1.00 32.20  ? 647  ASN A O   1 
ATOM 3825 C CB  . ASN A 1 647  ? 151.568 163.038 156.185 1.00 26.97  ? 647  ASN A CB  1 
ATOM 3826 C CG  . ASN A 1 647  ? 151.751 163.346 154.712 1.00 35.65  ? 647  ASN A CG  1 
ATOM 3827 O OD1 . ASN A 1 647  ? 150.877 163.070 153.891 1.00 35.66  ? 647  ASN A OD1 1 
ATOM 3828 N ND2 . ASN A 1 647  ? 152.900 163.915 154.369 1.00 35.96  ? 647  ASN A ND2 1 
ATOM 3829 N N   . TRP A 1 648  ? 149.695 160.612 156.802 1.00 21.32  ? 648  TRP A N   1 
ATOM 3830 C CA  . TRP A 1 648  ? 149.068 159.345 156.428 1.00 23.25  ? 648  TRP A CA  1 
ATOM 3831 C C   . TRP A 1 648  ? 147.554 159.432 156.548 1.00 27.45  ? 648  TRP A C   1 
ATOM 3832 O O   . TRP A 1 648  ? 146.820 158.979 155.659 1.00 26.37  ? 648  TRP A O   1 
ATOM 3833 C CB  . TRP A 1 648  ? 149.591 158.201 157.301 1.00 14.72  ? 648  TRP A CB  1 
ATOM 3834 C CG  . TRP A 1 648  ? 150.954 157.690 156.953 1.00 16.51  ? 648  TRP A CG  1 
ATOM 3835 C CD1 . TRP A 1 648  ? 152.150 158.212 157.336 1.00 20.45  ? 648  TRP A CD1 1 
ATOM 3836 C CD2 . TRP A 1 648  ? 151.256 156.542 156.157 1.00 17.05  ? 648  TRP A CD2 1 
ATOM 3837 N NE1 . TRP A 1 648  ? 153.181 157.466 156.827 1.00 20.62  ? 648  TRP A NE1 1 
ATOM 3838 C CE2 . TRP A 1 648  ? 152.658 156.433 156.097 1.00 17.36  ? 648  TRP A CE2 1 
ATOM 3839 C CE3 . TRP A 1 648  ? 150.477 155.598 155.486 1.00 19.60  ? 648  TRP A CE3 1 
ATOM 3840 C CZ2 . TRP A 1 648  ? 153.296 155.419 155.394 1.00 17.49  ? 648  TRP A CZ2 1 
ATOM 3841 C CZ3 . TRP A 1 648  ? 151.111 154.596 154.790 1.00 19.49  ? 648  TRP A CZ3 1 
ATOM 3842 C CH2 . TRP A 1 648  ? 152.507 154.512 154.749 1.00 17.89  ? 648  TRP A CH2 1 
ATOM 3843 N N   . GLU A 1 649  ? 147.068 160.004 157.652 1.00 31.41  ? 649  GLU A N   1 
ATOM 3844 C CA  . GLU A 1 649  ? 145.626 160.135 157.838 1.00 26.96  ? 649  GLU A CA  1 
ATOM 3845 C C   . GLU A 1 649  ? 145.004 160.984 156.737 1.00 32.15  ? 649  GLU A C   1 
ATOM 3846 O O   . GLU A 1 649  ? 143.968 160.618 156.162 1.00 32.93  ? 649  GLU A O   1 
ATOM 3847 C CB  . GLU A 1 649  ? 145.328 160.739 159.210 1.00 29.72  ? 649  GLU A CB  1 
ATOM 3848 C CG  . GLU A 1 649  ? 143.848 160.878 159.521 1.00 29.11  ? 649  GLU A CG  1 
ATOM 3849 C CD  . GLU A 1 649  ? 143.153 159.539 159.622 1.00 36.32  ? 649  GLU A CD  1 
ATOM 3850 O OE1 . GLU A 1 649  ? 143.833 158.547 159.936 1.00 39.28  ? 649  GLU A OE1 1 
ATOM 3851 O OE2 . GLU A 1 649  ? 141.929 159.477 159.387 1.00 37.26  ? 649  GLU A OE2 1 
ATOM 3852 N N   . ARG A 1 650  ? 145.637 162.114 156.416 1.00 33.41  ? 650  ARG A N   1 
ATOM 3853 C CA  . ARG A 1 650  ? 145.106 162.996 155.387 1.00 33.01  ? 650  ARG A CA  1 
ATOM 3854 C C   . ARG A 1 650  ? 145.103 162.322 154.022 1.00 34.26  ? 650  ARG A C   1 
ATOM 3855 O O   . ARG A 1 650  ? 144.126 162.432 153.276 1.00 38.28  ? 650  ARG A O   1 
ATOM 3856 C CB  . ARG A 1 650  ? 145.910 164.294 155.345 1.00 33.23  ? 650  ARG A CB  1 
ATOM 3857 C CG  . ARG A 1 650  ? 145.355 165.332 154.389 1.00 36.72  ? 650  ARG A CG  1 
ATOM 3858 C CD  . ARG A 1 650  ? 146.163 166.613 154.453 1.00 39.80  ? 650  ARG A CD  1 
ATOM 3859 N NE  . ARG A 1 650  ? 147.532 166.412 153.995 1.00 40.32  ? 650  ARG A NE  1 
ATOM 3860 C CZ  . ARG A 1 650  ? 148.601 166.507 154.772 1.00 42.12  ? 650  ARG A CZ  1 
ATOM 3861 N NH1 . ARG A 1 650  ? 148.497 166.798 156.059 1.00 38.56  ? 650  ARG A NH1 1 
ATOM 3862 N NH2 . ARG A 1 650  ? 149.806 166.304 154.246 1.00 40.27  ? 650  ARG A NH2 1 
ATOM 3863 N N   . GLU A 1 651  ? 146.184 161.617 153.672 1.00 32.85  ? 651  GLU A N   1 
ATOM 3864 C CA  . GLU A 1 651  ? 146.229 160.963 152.367 1.00 30.60  ? 651  GLU A CA  1 
ATOM 3865 C C   . GLU A 1 651  ? 145.197 159.848 152.276 1.00 30.07  ? 651  GLU A C   1 
ATOM 3866 O O   . GLU A 1 651  ? 144.565 159.669 151.230 1.00 37.08  ? 651  GLU A O   1 
ATOM 3867 C CB  . GLU A 1 651  ? 147.627 160.417 152.074 1.00 30.70  ? 651  GLU A CB  1 
ATOM 3868 C CG  . GLU A 1 651  ? 148.715 161.470 151.907 1.00 32.79  ? 651  GLU A CG  1 
ATOM 3869 C CD  . GLU A 1 651  ? 148.529 162.341 150.681 1.00 39.29  ? 651  GLU A CD  1 
ATOM 3870 O OE1 . GLU A 1 651  ? 148.000 161.858 149.682 1.00 40.46  ? 651  GLU A OE1 1 
ATOM 3871 O OE2 . GLU A 1 651  ? 148.920 163.525 150.723 1.00 40.93  ? 651  GLU A OE2 1 
ATOM 3872 N N   . LEU A 1 652  ? 145.009 159.087 153.359 1.00 25.27  ? 652  LEU A N   1 
ATOM 3873 C CA  . LEU A 1 652  ? 143.967 158.066 153.356 1.00 24.36  ? 652  LEU A CA  1 
ATOM 3874 C C   . LEU A 1 652  ? 142.591 158.686 153.163 1.00 30.77  ? 652  LEU A C   1 
ATOM 3875 O O   . LEU A 1 652  ? 141.760 158.153 152.418 1.00 33.05  ? 652  LEU A O   1 
ATOM 3876 C CB  . LEU A 1 652  ? 144.010 157.257 154.651 1.00 28.62  ? 652  LEU A CB  1 
ATOM 3877 C CG  . LEU A 1 652  ? 142.931 156.178 154.788 1.00 27.76  ? 652  LEU A CG  1 
ATOM 3878 C CD1 . LEU A 1 652  ? 143.095 155.084 153.750 1.00 31.79  ? 652  LEU A CD1 1 
ATOM 3879 C CD2 . LEU A 1 652  ? 142.958 155.588 156.178 1.00 23.76  ? 652  LEU A CD2 1 
ATOM 3880 N N   . ASN A 1 653  ? 142.328 159.815 153.826 1.00 35.58  ? 653  ASN A N   1 
ATOM 3881 C CA  . ASN A 1 653  ? 141.039 160.474 153.640 1.00 35.25  ? 653  ASN A CA  1 
ATOM 3882 C C   . ASN A 1 653  ? 140.883 161.024 152.226 1.00 35.18  ? 653  ASN A C   1 
ATOM 3883 O O   . ASN A 1 653  ? 139.770 161.038 151.689 1.00 35.23  ? 653  ASN A O   1 
ATOM 3884 C CB  . ASN A 1 653  ? 140.864 161.585 154.673 1.00 35.22  ? 653  ASN A CB  1 
ATOM 3885 C CG  . ASN A 1 653  ? 140.072 161.130 155.882 1.00 38.09  ? 653  ASN A CG  1 
ATOM 3886 O OD1 . ASN A 1 653  ? 138.990 160.558 155.749 1.00 37.19  ? 653  ASN A OD1 1 
ATOM 3887 N ND2 . ASN A 1 653  ? 140.609 161.378 157.070 1.00 39.38  ? 653  ASN A ND2 1 
ATOM 3888 N N   . ASN A 1 654  ? 141.977 161.478 151.609 1.00 33.94  ? 654  ASN A N   1 
ATOM 3889 C CA  . ASN A 1 654  ? 141.894 162.013 150.253 1.00 33.65  ? 654  ASN A CA  1 
ATOM 3890 C C   . ASN A 1 654  ? 141.654 160.914 149.224 1.00 35.78  ? 654  ASN A C   1 
ATOM 3891 O O   . ASN A 1 654  ? 140.819 161.072 148.326 1.00 42.83  ? 654  ASN A O   1 
ATOM 3892 C CB  . ASN A 1 654  ? 143.167 162.785 149.900 1.00 34.33  ? 654  ASN A CB  1 
ATOM 3893 C CG  . ASN A 1 654  ? 143.470 163.898 150.879 1.00 39.68  ? 654  ASN A CG  1 
ATOM 3894 O OD1 . ASN A 1 654  ? 142.625 164.277 151.689 1.00 40.17  ? 654  ASN A OD1 1 
ATOM 3895 N ND2 . ASN A 1 654  ? 144.686 164.429 150.812 1.00 36.24  ? 654  ASN A ND2 1 
ATOM 3896 N N   . PHE A 1 655  ? 142.374 159.796 149.331 1.00 28.72  ? 655  PHE A N   1 
ATOM 3897 C CA  . PHE A 1 655  ? 142.382 158.807 148.260 1.00 28.12  ? 655  PHE A CA  1 
ATOM 3898 C C   . PHE A 1 655  ? 141.272 157.768 148.366 1.00 28.83  ? 655  PHE A C   1 
ATOM 3899 O O   . PHE A 1 655  ? 140.817 157.272 147.330 1.00 30.71  ? 655  PHE A O   1 
ATOM 3900 C CB  . PHE A 1 655  ? 143.728 158.072 148.211 1.00 31.31  ? 655  PHE A CB  1 
ATOM 3901 C CG  . PHE A 1 655  ? 144.902 158.951 147.888 1.00 31.39  ? 655  PHE A CG  1 
ATOM 3902 C CD1 . PHE A 1 655  ? 144.899 159.753 146.762 1.00 31.99  ? 655  PHE A CD1 1 
ATOM 3903 C CD2 . PHE A 1 655  ? 146.029 158.940 148.690 1.00 29.82  ? 655  PHE A CD2 1 
ATOM 3904 C CE1 . PHE A 1 655  ? 145.986 160.551 146.459 1.00 34.20  ? 655  PHE A CE1 1 
ATOM 3905 C CE2 . PHE A 1 655  ? 147.112 159.719 148.383 1.00 32.86  ? 655  PHE A CE2 1 
ATOM 3906 C CZ  . PHE A 1 655  ? 147.094 160.538 147.271 1.00 33.94  ? 655  PHE A CZ  1 
ATOM 3907 N N   . PHE A 1 656  ? 140.824 157.421 149.571 1.00 31.39  ? 656  PHE A N   1 
ATOM 3908 C CA  . PHE A 1 656  ? 139.924 156.291 149.755 1.00 31.93  ? 656  PHE A CA  1 
ATOM 3909 C C   . PHE A 1 656  ? 138.636 156.728 150.436 1.00 28.04  ? 656  PHE A C   1 
ATOM 3910 O O   . PHE A 1 656  ? 138.576 157.760 151.108 1.00 31.70  ? 656  PHE A O   1 
ATOM 3911 C CB  . PHE A 1 656  ? 140.568 155.160 150.582 1.00 28.74  ? 656  PHE A CB  1 
ATOM 3912 C CG  . PHE A 1 656  ? 141.906 154.707 150.071 1.00 24.52  ? 656  PHE A CG  1 
ATOM 3913 C CD1 . PHE A 1 656  ? 143.038 155.480 150.254 1.00 23.20  ? 656  PHE A CD1 1 
ATOM 3914 C CD2 . PHE A 1 656  ? 142.029 153.503 149.401 1.00 27.54  ? 656  PHE A CD2 1 
ATOM 3915 C CE1 . PHE A 1 656  ? 144.264 155.064 149.781 1.00 21.39  ? 656  PHE A CE1 1 
ATOM 3916 C CE2 . PHE A 1 656  ? 143.254 153.082 148.926 1.00 26.30  ? 656  PHE A CE2 1 
ATOM 3917 C CZ  . PHE A 1 656  ? 144.372 153.865 149.116 1.00 24.45  ? 656  PHE A CZ  1 
ATOM 3918 N N   . TYR A 1 657  ? 137.598 155.914 150.249 1.00 30.77  ? 657  TYR A N   1 
ATOM 3919 C CA  . TYR A 1 657  ? 136.337 156.067 150.970 1.00 35.83  ? 657  TYR A CA  1 
ATOM 3920 C C   . TYR A 1 657  ? 136.509 155.429 152.343 1.00 39.74  ? 657  TYR A C   1 
ATOM 3921 O O   . TYR A 1 657  ? 136.493 154.204 152.483 1.00 40.66  ? 657  TYR A O   1 
ATOM 3922 C CB  . TYR A 1 657  ? 135.189 155.432 150.194 1.00 33.99  ? 657  TYR A CB  1 
ATOM 3923 C CG  . TYR A 1 657  ? 134.858 156.143 148.901 1.00 36.42  ? 657  TYR A CG  1 
ATOM 3924 C CD1 . TYR A 1 657  ? 134.313 157.420 148.907 1.00 38.27  ? 657  TYR A CD1 1 
ATOM 3925 C CD2 . TYR A 1 657  ? 135.090 155.536 147.674 1.00 37.45  ? 657  TYR A CD2 1 
ATOM 3926 C CE1 . TYR A 1 657  ? 134.008 158.072 147.727 1.00 36.51  ? 657  TYR A CE1 1 
ATOM 3927 C CE2 . TYR A 1 657  ? 134.789 156.181 146.489 1.00 37.44  ? 657  TYR A CE2 1 
ATOM 3928 C CZ  . TYR A 1 657  ? 134.249 157.449 146.522 1.00 37.09  ? 657  TYR A CZ  1 
ATOM 3929 O OH  . TYR A 1 657  ? 133.948 158.094 145.345 1.00 36.76  ? 657  TYR A OH  1 
ATOM 3930 N N   . THR A 1 658  ? 136.668 156.271 153.365 1.00 31.86  ? 658  THR A N   1 
ATOM 3931 C CA  . THR A 1 658  ? 137.027 155.825 154.706 1.00 31.73  ? 658  THR A CA  1 
ATOM 3932 C C   . THR A 1 658  ? 135.875 155.127 155.428 1.00 35.45  ? 658  THR A C   1 
ATOM 3933 O O   . THR A 1 658  ? 136.105 154.514 156.476 1.00 36.78  ? 658  THR A O   1 
ATOM 3934 C CB  . THR A 1 658  ? 137.528 157.038 155.504 1.00 35.10  ? 658  THR A CB  1 
ATOM 3935 O OG1 . THR A 1 658  ? 138.559 157.695 154.758 1.00 33.60  ? 658  THR A OG1 1 
ATOM 3936 C CG2 . THR A 1 658  ? 138.113 156.631 156.848 1.00 34.79  ? 658  THR A CG2 1 
ATOM 3937 N N   . ALA A 1 659  ? 134.660 155.168 154.873 1.00 38.19  ? 659  ALA A N   1 
ATOM 3938 C CA  . ALA A 1 659  ? 133.490 154.646 155.577 1.00 40.22  ? 659  ALA A CA  1 
ATOM 3939 C C   . ALA A 1 659  ? 133.688 153.197 156.008 1.00 37.44  ? 659  ALA A C   1 
ATOM 3940 O O   . ALA A 1 659  ? 133.287 152.810 157.112 1.00 38.53  ? 659  ALA A O   1 
ATOM 3941 C CB  . ALA A 1 659  ? 132.248 154.777 154.696 1.00 36.56  ? 659  ALA A CB  1 
ATOM 3942 N N   . GLY A 1 660  ? 134.299 152.383 155.156 1.00 34.57  ? 660  GLY A N   1 
ATOM 3943 C CA  . GLY A 1 660  ? 134.611 151.013 155.499 1.00 36.09  ? 660  GLY A CA  1 
ATOM 3944 C C   . GLY A 1 660  ? 135.975 150.802 156.115 1.00 36.52  ? 660  GLY A C   1 
ATOM 3945 O O   . GLY A 1 660  ? 136.375 149.652 156.326 1.00 34.07  ? 660  GLY A O   1 
ATOM 3946 N N   . ILE A 1 661  ? 136.705 151.873 156.413 1.00 30.43  ? 661  ILE A N   1 
ATOM 3947 C CA  . ILE A 1 661  ? 138.069 151.766 156.926 1.00 24.64  ? 661  ILE A CA  1 
ATOM 3948 C C   . ILE A 1 661  ? 138.172 152.590 158.203 1.00 28.05  ? 661  ILE A C   1 
ATOM 3949 O O   . ILE A 1 661  ? 138.616 153.747 158.158 1.00 25.98  ? 661  ILE A O   1 
ATOM 3950 C CB  . ILE A 1 661  ? 139.094 152.236 155.882 1.00 26.68  ? 661  ILE A CB  1 
ATOM 3951 C CG1 . ILE A 1 661  ? 138.969 151.415 154.602 1.00 26.14  ? 661  ILE A CG1 1 
ATOM 3952 C CG2 . ILE A 1 661  ? 140.511 152.090 156.415 1.00 26.57  ? 661  ILE A CG2 1 
ATOM 3953 C CD1 . ILE A 1 661  ? 139.166 152.240 153.358 1.00 28.02  ? 661  ILE A CD1 1 
ATOM 3954 N N   . PRO A 1 662  ? 137.764 152.060 159.351 1.00 22.76  ? 662  PRO A N   1 
ATOM 3955 C CA  . PRO A 1 662  ? 137.926 152.806 160.601 1.00 14.76  ? 662  PRO A CA  1 
ATOM 3956 C C   . PRO A 1 662  ? 139.399 152.917 160.961 1.00 14.36  ? 662  PRO A C   1 
ATOM 3957 O O   . PRO A 1 662  ? 140.183 151.989 160.746 1.00 20.58  ? 662  PRO A O   1 
ATOM 3958 C CB  . PRO A 1 662  ? 137.150 151.943 161.609 1.00 18.56  ? 662  PRO A CB  1 
ATOM 3959 C CG  . PRO A 1 662  ? 136.264 151.076 160.685 1.00 21.85  ? 662  PRO A CG  1 
ATOM 3960 C CD  . PRO A 1 662  ? 137.280 150.715 159.677 1.00 16.99  ? 662  PRO A CD  1 
ATOM 3961 N N   . VAL A 1 663  ? 139.776 154.066 161.512 1.00 8.42   ? 663  VAL A N   1 
ATOM 3962 C CA  . VAL A 1 663  ? 141.167 154.363 161.828 1.00 7.70   ? 663  VAL A CA  1 
ATOM 3963 C C   . VAL A 1 663  ? 141.254 154.844 163.268 1.00 18.16  ? 663  VAL A C   1 
ATOM 3964 O O   . VAL A 1 663  ? 140.463 155.693 163.693 1.00 24.09  ? 663  VAL A O   1 
ATOM 3965 C CB  . VAL A 1 663  ? 141.758 155.414 160.870 1.00 3.93   ? 663  VAL A CB  1 
ATOM 3966 C CG1 . VAL A 1 663  ? 143.073 155.932 161.407 1.00 4.17   ? 663  VAL A CG1 1 
ATOM 3967 C CG2 . VAL A 1 663  ? 141.947 154.816 159.494 1.00 13.56  ? 663  VAL A CG2 1 
ATOM 3968 N N   . LEU A 1 664  ? 142.211 154.301 164.014 1.00 12.47  ? 664  LEU A N   1 
ATOM 3969 C CA  . LEU A 1 664  ? 142.494 154.724 165.379 1.00 11.25  ? 664  LEU A CA  1 
ATOM 3970 C C   . LEU A 1 664  ? 143.837 155.442 165.389 1.00 9.08   ? 664  LEU A C   1 
ATOM 3971 O O   . LEU A 1 664  ? 144.842 154.890 164.934 1.00 10.33  ? 664  LEU A O   1 
ATOM 3972 C CB  . LEU A 1 664  ? 142.507 153.527 166.329 1.00 14.65  ? 664  LEU A CB  1 
ATOM 3973 C CG  . LEU A 1 664  ? 143.072 153.747 167.732 1.00 14.42  ? 664  LEU A CG  1 
ATOM 3974 C CD1 . LEU A 1 664  ? 142.272 154.807 168.458 1.00 11.50  ? 664  LEU A CD1 1 
ATOM 3975 C CD2 . LEU A 1 664  ? 143.075 152.448 168.517 1.00 13.49  ? 664  LEU A CD2 1 
ATOM 3976 N N   . LYS A 1 665  ? 143.848 156.669 165.900 1.00 13.71  ? 665  LYS A N   1 
ATOM 3977 C CA  . LYS A 1 665  ? 145.051 157.498 165.949 1.00 13.93  ? 665  LYS A CA  1 
ATOM 3978 C C   . LYS A 1 665  ? 145.602 157.440 167.370 1.00 20.89  ? 665  LYS A C   1 
ATOM 3979 O O   . LYS A 1 665  ? 145.222 158.240 168.226 1.00 23.16  ? 665  LYS A O   1 
ATOM 3980 C CB  . LYS A 1 665  ? 144.728 158.927 165.525 1.00 15.56  ? 665  LYS A CB  1 
ATOM 3981 C CG  . LYS A 1 665  ? 145.908 159.885 165.534 1.00 20.38  ? 665  LYS A CG  1 
ATOM 3982 C CD  . LYS A 1 665  ? 146.924 159.529 164.467 1.00 21.24  ? 665  LYS A CD  1 
ATOM 3983 C CE  . LYS A 1 665  ? 148.016 160.579 164.376 1.00 23.27  ? 665  LYS A CE  1 
ATOM 3984 N NZ  . LYS A 1 665  ? 148.851 160.625 165.604 1.00 20.28  ? 665  LYS A NZ  1 
ATOM 3985 N N   . LEU A 1 666  ? 146.510 156.495 167.619 1.00 16.60  ? 666  LEU A N   1 
ATOM 3986 C CA  . LEU A 1 666  ? 147.030 156.257 168.966 1.00 13.90  ? 666  LEU A CA  1 
ATOM 3987 C C   . LEU A 1 666  ? 148.119 157.281 169.291 1.00 15.42  ? 666  LEU A C   1 
ATOM 3988 O O   . LEU A 1 666  ? 149.302 156.969 169.436 1.00 13.60  ? 666  LEU A O   1 
ATOM 3989 C CB  . LEU A 1 666  ? 147.548 154.831 169.092 1.00 15.00  ? 666  LEU A CB  1 
ATOM 3990 C CG  . LEU A 1 666  ? 147.669 154.278 170.514 1.00 16.93  ? 666  LEU A CG  1 
ATOM 3991 C CD1 . LEU A 1 666  ? 146.302 153.904 171.062 1.00 17.48  ? 666  LEU A CD1 1 
ATOM 3992 C CD2 . LEU A 1 666  ? 148.610 153.086 170.553 1.00 10.76  ? 666  LEU A CD2 1 
ATOM 3993 N N   . TYR A 1 667  ? 147.688 158.535 169.409 1.00 22.17  ? 667  TYR A N   1 
ATOM 3994 C CA  . TYR A 1 667  ? 148.570 159.620 169.813 1.00 22.68  ? 667  TYR A CA  1 
ATOM 3995 C C   . TYR A 1 667  ? 147.722 160.812 170.233 1.00 28.17  ? 667  TYR A C   1 
ATOM 3996 O O   . TYR A 1 667  ? 146.607 161.001 169.739 1.00 28.03  ? 667  TYR A O   1 
ATOM 3997 C CB  . TYR A 1 667  ? 149.534 160.018 168.689 1.00 21.35  ? 667  TYR A CB  1 
ATOM 3998 C CG  . TYR A 1 667  ? 150.387 161.226 169.006 1.00 26.37  ? 667  TYR A CG  1 
ATOM 3999 C CD1 . TYR A 1 667  ? 150.001 162.499 168.605 1.00 26.02  ? 667  TYR A CD1 1 
ATOM 4000 C CD2 . TYR A 1 667  ? 151.577 161.095 169.710 1.00 25.27  ? 667  TYR A CD2 1 
ATOM 4001 C CE1 . TYR A 1 667  ? 150.774 163.605 168.895 1.00 28.69  ? 667  TYR A CE1 1 
ATOM 4002 C CE2 . TYR A 1 667  ? 152.359 162.196 170.002 1.00 25.53  ? 667  TYR A CE2 1 
ATOM 4003 C CZ  . TYR A 1 667  ? 151.953 163.448 169.593 1.00 31.85  ? 667  TYR A CZ  1 
ATOM 4004 O OH  . TYR A 1 667  ? 152.729 164.547 169.882 1.00 29.92  ? 667  TYR A OH  1 
ATOM 4005 N N   . GLY A 1 668  ? 148.264 161.608 171.148 1.00 26.98  ? 668  GLY A N   1 
ATOM 4006 C CA  . GLY A 1 668  ? 147.592 162.835 171.551 1.00 27.95  ? 668  GLY A CA  1 
ATOM 4007 C C   . GLY A 1 668  ? 146.472 162.555 172.524 1.00 31.77  ? 668  GLY A C   1 
ATOM 4008 O O   . GLY A 1 668  ? 146.625 161.766 173.456 1.00 29.95  ? 668  GLY A O   1 
ATOM 4009 N N   . GLU A 1 669  ? 145.333 163.217 172.313 1.00 32.75  ? 669  GLU A N   1 
ATOM 4010 C CA  . GLU A 1 669  ? 144.185 163.029 173.196 1.00 31.06  ? 669  GLU A CA  1 
ATOM 4011 C C   . GLU A 1 669  ? 143.635 161.612 173.098 1.00 29.46  ? 669  GLU A C   1 
ATOM 4012 O O   . GLU A 1 669  ? 143.158 161.051 174.094 1.00 28.01  ? 669  GLU A O   1 
ATOM 4013 C CB  . GLU A 1 669  ? 143.100 164.053 172.856 1.00 29.60  ? 669  GLU A CB  1 
ATOM 4014 C CG  . GLU A 1 669  ? 141.863 163.989 173.738 1.00 31.54  ? 669  GLU A CG  1 
ATOM 4015 C CD  . GLU A 1 669  ? 142.150 164.344 175.183 1.00 33.66  ? 669  GLU A CD  1 
ATOM 4016 O OE1 . GLU A 1 669  ? 143.123 165.086 175.435 1.00 37.29  ? 669  GLU A OE1 1 
ATOM 4017 O OE2 . GLU A 1 669  ? 141.399 163.883 176.068 1.00 31.28  ? 669  GLU A OE2 1 
ATOM 4018 N N   . THR A 1 670  ? 143.696 161.017 171.905 1.00 26.52  ? 670  THR A N   1 
ATOM 4019 C CA  . THR A 1 670  ? 143.052 159.728 171.681 1.00 28.07  ? 670  THR A CA  1 
ATOM 4020 C C   . THR A 1 670  ? 143.692 158.615 172.505 1.00 27.26  ? 670  THR A C   1 
ATOM 4021 O O   . THR A 1 670  ? 142.979 157.746 173.019 1.00 29.60  ? 670  THR A O   1 
ATOM 4022 C CB  . THR A 1 670  ? 143.081 159.385 170.193 1.00 29.78  ? 670  THR A CB  1 
ATOM 4023 O OG1 . THR A 1 670  ? 142.384 160.398 169.456 1.00 28.08  ? 670  THR A OG1 1 
ATOM 4024 C CG2 . THR A 1 670  ? 142.408 158.051 169.943 1.00 26.25  ? 670  THR A CG2 1 
ATOM 4025 N N   . ILE A 1 671  ? 145.020 158.619 172.651 1.00 21.39  ? 671  ILE A N   1 
ATOM 4026 C CA  . ILE A 1 671  ? 145.657 157.587 173.464 1.00 24.34  ? 671  ILE A CA  1 
ATOM 4027 C C   . ILE A 1 671  ? 145.310 157.761 174.938 1.00 26.90  ? 671  ILE A C   1 
ATOM 4028 O O   . ILE A 1 671  ? 145.087 156.777 175.652 1.00 25.54  ? 671  ILE A O   1 
ATOM 4029 C CB  . ILE A 1 671  ? 147.180 157.552 173.233 1.00 19.80  ? 671  ILE A CB  1 
ATOM 4030 C CG1 . ILE A 1 671  ? 147.761 156.310 173.908 1.00 17.86  ? 671  ILE A CG1 1 
ATOM 4031 C CG2 . ILE A 1 671  ? 147.860 158.826 173.712 1.00 22.90  ? 671  ILE A CG2 1 
ATOM 4032 C CD1 . ILE A 1 671  ? 149.149 155.994 173.507 1.00 25.44  ? 671  ILE A CD1 1 
ATOM 4033 N N   . LYS A 1 672  ? 145.258 159.004 175.424 1.00 29.17  ? 672  LYS A N   1 
ATOM 4034 C CA  . LYS A 1 672  ? 144.844 159.216 176.808 1.00 26.64  ? 672  LYS A CA  1 
ATOM 4035 C C   . LYS A 1 672  ? 143.389 158.822 177.014 1.00 23.61  ? 672  LYS A C   1 
ATOM 4036 O O   . LYS A 1 672  ? 142.990 158.488 178.135 1.00 21.93  ? 672  LYS A O   1 
ATOM 4037 C CB  . LYS A 1 672  ? 145.071 160.670 177.226 1.00 21.04  ? 672  LYS A CB  1 
ATOM 4038 C CG  . LYS A 1 672  ? 146.512 161.012 177.612 1.00 24.95  ? 672  LYS A CG  1 
ATOM 4039 C CD  . LYS A 1 672  ? 147.433 161.083 176.405 1.00 27.47  ? 672  LYS A CD  1 
ATOM 4040 C CE  . LYS A 1 672  ? 148.838 161.515 176.789 1.00 30.11  ? 672  LYS A CE  1 
ATOM 4041 N NZ  . LYS A 1 672  ? 149.764 161.470 175.622 1.00 25.74  ? 672  LYS A NZ  1 
ATOM 4042 N N   . ALA A 1 673  ? 142.586 158.850 175.948 1.00 20.52  ? 673  ALA A N   1 
ATOM 4043 C CA  . ALA A 1 673  ? 141.202 158.402 176.055 1.00 19.75  ? 673  ALA A CA  1 
ATOM 4044 C C   . ALA A 1 673  ? 141.114 156.895 176.271 1.00 22.30  ? 673  ALA A C   1 
ATOM 4045 O O   . ALA A 1 673  ? 140.249 156.421 177.016 1.00 26.59  ? 673  ALA A O   1 
ATOM 4046 C CB  . ALA A 1 673  ? 140.422 158.810 174.806 1.00 24.26  ? 673  ALA A CB  1 
ATOM 4047 N N   . VAL A 1 674  ? 141.995 156.125 175.630 1.00 21.55  ? 674  VAL A N   1 
ATOM 4048 C CA  . VAL A 1 674  ? 141.921 154.666 175.658 1.00 21.45  ? 674  VAL A CA  1 
ATOM 4049 C C   . VAL A 1 674  ? 142.888 154.059 176.670 1.00 19.05  ? 674  VAL A C   1 
ATOM 4050 O O   . VAL A 1 674  ? 143.187 152.864 176.593 1.00 17.64  ? 674  VAL A O   1 
ATOM 4051 C CB  . VAL A 1 674  ? 142.162 154.074 174.261 1.00 23.82  ? 674  VAL A CB  1 
ATOM 4052 C CG1 . VAL A 1 674  ? 141.089 154.544 173.292 1.00 22.65  ? 674  VAL A CG1 1 
ATOM 4053 C CG2 . VAL A 1 674  ? 143.545 154.451 173.755 1.00 21.74  ? 674  VAL A CG2 1 
ATOM 4054 N N   . LYS A 1 675  ? 143.376 154.848 177.620 1.00 24.77  ? 675  LYS A N   1 
ATOM 4055 C CA  . LYS A 1 675  ? 144.342 154.373 178.597 1.00 16.47  ? 675  LYS A CA  1 
ATOM 4056 C C   . LYS A 1 675  ? 143.669 154.105 179.939 1.00 19.55  ? 675  LYS A C   1 
ATOM 4057 O O   . LYS A 1 675  ? 142.700 154.770 180.314 1.00 23.29  ? 675  LYS A O   1 
ATOM 4058 C CB  . LYS A 1 675  ? 145.466 155.397 178.773 1.00 14.31  ? 675  LYS A CB  1 
ATOM 4059 C CG  . LYS A 1 675  ? 146.598 154.945 179.676 1.00 21.55  ? 675  LYS A CG  1 
ATOM 4060 C CD  . LYS A 1 675  ? 147.633 156.040 179.850 1.00 22.86  ? 675  LYS A CD  1 
ATOM 4061 C CE  . LYS A 1 675  ? 148.468 156.213 178.597 1.00 21.11  ? 675  LYS A CE  1 
ATOM 4062 N NZ  . LYS A 1 675  ? 149.557 157.202 178.807 1.00 20.61  ? 675  LYS A NZ  1 
ATOM 4063 N N   . TYR A 1 676  ? 144.187 153.109 180.653 1.00 15.79  ? 676  TYR A N   1 
ATOM 4064 C CA  . TYR A 1 676  ? 143.738 152.856 182.013 1.00 17.15  ? 676  TYR A CA  1 
ATOM 4065 C C   . TYR A 1 676  ? 144.076 154.038 182.917 1.00 26.53  ? 676  TYR A C   1 
ATOM 4066 O O   . TYR A 1 676  ? 145.153 154.629 182.792 1.00 24.37  ? 676  TYR A O   1 
ATOM 4067 C CB  . TYR A 1 676  ? 144.401 151.603 182.583 1.00 12.23  ? 676  TYR A CB  1 
ATOM 4068 C CG  . TYR A 1 676  ? 143.627 150.320 182.426 1.00 16.36  ? 676  TYR A CG  1 
ATOM 4069 C CD1 . TYR A 1 676  ? 142.396 150.151 183.044 1.00 18.72  ? 676  TYR A CD1 1 
ATOM 4070 C CD2 . TYR A 1 676  ? 144.148 149.258 181.703 1.00 20.10  ? 676  TYR A CD2 1 
ATOM 4071 C CE1 . TYR A 1 676  ? 141.693 148.972 182.919 1.00 18.06  ? 676  TYR A CE1 1 
ATOM 4072 C CE2 . TYR A 1 676  ? 143.452 148.074 181.573 1.00 20.05  ? 676  TYR A CE2 1 
ATOM 4073 C CZ  . TYR A 1 676  ? 142.225 147.937 182.183 1.00 21.11  ? 676  TYR A CZ  1 
ATOM 4074 O OH  . TYR A 1 676  ? 141.528 146.759 182.058 1.00 23.53  ? 676  TYR A OH  1 
ATOM 4075 N N   . PRO A 1 677  ? 143.180 154.412 183.828 1.00 30.70  ? 677  PRO A N   1 
ATOM 4076 C CA  . PRO A 1 677  ? 143.623 155.149 185.014 1.00 29.41  ? 677  PRO A CA  1 
ATOM 4077 C C   . PRO A 1 677  ? 144.569 154.276 185.824 1.00 26.04  ? 677  PRO A C   1 
ATOM 4078 O O   . PRO A 1 677  ? 144.419 153.053 185.874 1.00 21.55  ? 677  PRO A O   1 
ATOM 4079 C CB  . PRO A 1 677  ? 142.317 155.432 185.765 1.00 28.96  ? 677  PRO A CB  1 
ATOM 4080 C CG  . PRO A 1 677  ? 141.266 155.395 184.705 1.00 24.52  ? 677  PRO A CG  1 
ATOM 4081 C CD  . PRO A 1 677  ? 141.714 154.326 183.749 1.00 24.34  ? 677  PRO A CD  1 
ATOM 4082 N N   . LYS A 1 678  ? 145.554 154.913 186.460 1.00 27.26  ? 678  LYS A N   1 
ATOM 4083 C CA  . LYS A 1 678  ? 146.621 154.154 187.105 1.00 28.69  ? 678  LYS A CA  1 
ATOM 4084 C C   . LYS A 1 678  ? 146.090 153.245 188.208 1.00 30.55  ? 678  LYS A C   1 
ATOM 4085 O O   . LYS A 1 678  ? 146.720 152.231 188.532 1.00 28.96  ? 678  LYS A O   1 
ATOM 4086 C CB  . LYS A 1 678  ? 147.679 155.109 187.658 1.00 27.19  ? 678  LYS A CB  1 
ATOM 4087 C CG  . LYS A 1 678  ? 148.953 154.424 188.127 1.00 26.41  ? 678  LYS A CG  1 
ATOM 4088 C CD  . LYS A 1 678  ? 150.070 155.430 188.340 1.00 26.55  ? 678  LYS A CD  1 
ATOM 4089 C CE  . LYS A 1 678  ? 150.128 156.432 187.198 1.00 26.21  ? 678  LYS A CE  1 
ATOM 4090 N NZ  . LYS A 1 678  ? 151.381 157.232 187.213 1.00 23.26  ? 678  LYS A NZ  1 
ATOM 4091 N N   . GLN A 1 679  ? 144.936 153.575 188.785 1.00 30.39  ? 679  GLN A N   1 
ATOM 4092 C CA  . GLN A 1 679  ? 144.353 152.770 189.849 1.00 30.76  ? 679  GLN A CA  1 
ATOM 4093 C C   . GLN A 1 679  ? 143.429 151.668 189.341 1.00 33.76  ? 679  GLN A C   1 
ATOM 4094 O O   . GLN A 1 679  ? 142.996 150.833 190.142 1.00 31.98  ? 679  GLN A O   1 
ATOM 4095 C CB  . GLN A 1 679  ? 143.580 153.666 190.824 1.00 31.06  ? 679  GLN A CB  1 
ATOM 4096 C CG  . GLN A 1 679  ? 142.303 154.264 190.249 1.00 30.70  ? 679  GLN A CG  1 
ATOM 4097 C CD  . GLN A 1 679  ? 142.551 155.539 189.463 1.00 35.74  ? 679  GLN A CD  1 
ATOM 4098 O OE1 . GLN A 1 679  ? 143.682 155.835 189.077 1.00 32.47  ? 679  GLN A OE1 1 
ATOM 4099 N NE2 . GLN A 1 679  ? 141.490 156.299 189.220 1.00 35.75  ? 679  GLN A NE2 1 
ATOM 4100 N N   . ALA A 1 680  ? 143.119 151.640 188.045 1.00 28.70  ? 680  ALA A N   1 
ATOM 4101 C CA  . ALA A 1 680  ? 142.180 150.673 187.486 1.00 26.72  ? 680  ALA A CA  1 
ATOM 4102 C C   . ALA A 1 680  ? 142.861 149.489 186.812 1.00 21.48  ? 680  ALA A C   1 
ATOM 4103 O O   . ALA A 1 680  ? 142.170 148.591 186.323 1.00 20.83  ? 680  ALA A O   1 
ATOM 4104 C CB  . ALA A 1 680  ? 141.248 151.365 186.488 1.00 25.05  ? 680  ALA A CB  1 
ATOM 4105 N N   . ILE A 1 681  ? 144.187 149.464 186.777 1.00 18.00  ? 681  ILE A N   1 
ATOM 4106 C CA  . ILE A 1 681  ? 144.932 148.355 186.161 1.00 19.79  ? 681  ILE A CA  1 
ATOM 4107 C C   . ILE A 1 681  ? 144.714 147.087 186.977 1.00 18.04  ? 681  ILE A C   1 
ATOM 4108 O O   . ILE A 1 681  ? 144.584 147.176 188.210 1.00 24.29  ? 681  ILE A O   1 
ATOM 4109 C CB  . ILE A 1 681  ? 146.418 148.727 186.078 1.00 21.49  ? 681  ILE A CB  1 
ATOM 4110 C CG1 . ILE A 1 681  ? 146.567 150.144 185.522 1.00 21.50  ? 681  ILE A CG1 1 
ATOM 4111 C CG2 . ILE A 1 681  ? 147.195 147.764 185.200 1.00 17.81  ? 681  ILE A CG2 1 
ATOM 4112 C CD1 . ILE A 1 681  ? 147.995 150.596 185.373 1.00 14.79  ? 681  ILE A CD1 1 
ATOM 4113 N N   . PRO A 1 682  ? 144.608 145.900 186.357 1.00 18.43  ? 682  PRO A N   1 
ATOM 4114 C CA  . PRO A 1 682  ? 144.393 144.678 187.135 1.00 24.82  ? 682  PRO A CA  1 
ATOM 4115 C C   . PRO A 1 682  ? 145.455 144.457 188.196 1.00 31.27  ? 682  PRO A C   1 
ATOM 4116 O O   . PRO A 1 682  ? 146.579 144.950 188.100 1.00 33.87  ? 682  PRO A O   1 
ATOM 4117 C CB  . PRO A 1 682  ? 144.432 143.586 186.064 1.00 24.55  ? 682  PRO A CB  1 
ATOM 4118 C CG  . PRO A 1 682  ? 143.957 144.251 184.826 1.00 24.94  ? 682  PRO A CG  1 
ATOM 4119 C CD  . PRO A 1 682  ? 143.911 145.757 185.059 1.00 24.87  ? 682  PRO A CD  1 
ATOM 4120 N N   . ALA A 1 683  ? 145.059 143.707 189.224 1.00 27.45  ? 683  ALA A N   1 
ATOM 4121 C CA  . ALA A 1 683  ? 145.899 143.553 190.406 1.00 27.00  ? 683  ALA A CA  1 
ATOM 4122 C C   . ALA A 1 683  ? 147.213 142.854 190.082 1.00 26.22  ? 683  ALA A C   1 
ATOM 4123 O O   . ALA A 1 683  ? 148.275 143.267 190.561 1.00 29.45  ? 683  ALA A O   1 
ATOM 4124 C CB  . ALA A 1 683  ? 145.140 142.791 191.491 1.00 27.87  ? 683  ALA A CB  1 
ATOM 4125 N N   . HIS A 1 684  ? 147.168 141.788 189.280 1.00 22.87  ? 684  HIS A N   1 
ATOM 4126 C CA  . HIS A 1 684  ? 148.395 141.061 188.970 1.00 26.47  ? 684  HIS A CA  1 
ATOM 4127 C C   . HIS A 1 684  ? 149.322 141.892 188.091 1.00 27.61  ? 684  HIS A C   1 
ATOM 4128 O O   . HIS A 1 684  ? 150.549 141.814 188.222 1.00 29.04  ? 684  HIS A O   1 
ATOM 4129 C CB  . HIS A 1 684  ? 148.066 139.722 188.308 1.00 23.35  ? 684  HIS A CB  1 
ATOM 4130 C CG  . HIS A 1 684  ? 147.420 139.850 186.964 1.00 27.94  ? 684  HIS A CG  1 
ATOM 4131 N ND1 . HIS A 1 684  ? 148.074 139.537 185.792 1.00 26.59  ? 684  HIS A ND1 1 
ATOM 4132 C CD2 . HIS A 1 684  ? 146.178 140.252 186.606 1.00 27.32  ? 684  HIS A CD2 1 
ATOM 4133 C CE1 . HIS A 1 684  ? 147.264 139.743 184.770 1.00 25.63  ? 684  HIS A CE1 1 
ATOM 4134 N NE2 . HIS A 1 684  ? 146.107 140.177 185.236 1.00 29.81  ? 684  HIS A NE2 1 
ATOM 4135 N N   . LEU A 1 685  ? 148.755 142.701 187.195 1.00 22.20  ? 685  LEU A N   1 
ATOM 4136 C CA  . LEU A 1 685  ? 149.582 143.558 186.354 1.00 23.28  ? 685  LEU A CA  1 
ATOM 4137 C C   . LEU A 1 685  ? 150.229 144.673 187.167 1.00 19.40  ? 685  LEU A C   1 
ATOM 4138 O O   . LEU A 1 685  ? 151.379 145.046 186.910 1.00 24.45  ? 685  LEU A O   1 
ATOM 4139 C CB  . LEU A 1 685  ? 148.747 144.120 185.207 1.00 19.35  ? 685  LEU A CB  1 
ATOM 4140 C CG  . LEU A 1 685  ? 148.546 143.097 184.088 1.00 14.20  ? 685  LEU A CG  1 
ATOM 4141 C CD1 . LEU A 1 685  ? 148.097 143.750 182.813 1.00 17.24  ? 685  LEU A CD1 1 
ATOM 4142 C CD2 . LEU A 1 685  ? 149.825 142.312 183.858 1.00 14.92  ? 685  LEU A CD2 1 
ATOM 4143 N N   . GLN A 1 686  ? 149.509 145.218 188.150 1.00 15.11  ? 686  GLN A N   1 
ATOM 4144 C CA  . GLN A 1 686  ? 150.127 146.170 189.068 1.00 16.50  ? 686  GLN A CA  1 
ATOM 4145 C C   . GLN A 1 686  ? 151.207 145.500 189.907 1.00 19.55  ? 686  GLN A C   1 
ATOM 4146 O O   . GLN A 1 686  ? 152.243 146.109 190.199 1.00 23.72  ? 686  GLN A O   1 
ATOM 4147 C CB  . GLN A 1 686  ? 149.068 146.808 189.966 1.00 22.98  ? 686  GLN A CB  1 
ATOM 4148 C CG  . GLN A 1 686  ? 148.084 147.700 189.233 1.00 23.42  ? 686  GLN A CG  1 
ATOM 4149 C CD  . GLN A 1 686  ? 147.042 148.296 190.158 1.00 24.38  ? 686  GLN A CD  1 
ATOM 4150 O OE1 . GLN A 1 686  ? 147.009 147.994 191.350 1.00 27.79  ? 686  GLN A OE1 1 
ATOM 4151 N NE2 . GLN A 1 686  ? 146.188 149.153 189.613 1.00 24.05  ? 686  GLN A NE2 1 
ATOM 4152 N N   . SER A 1 687  ? 150.977 144.248 190.314 1.00 19.61  ? 687  SER A N   1 
ATOM 4153 C CA  . SER A 1 687  ? 152.003 143.497 191.028 1.00 18.31  ? 687  SER A CA  1 
ATOM 4154 C C   . SER A 1 687  ? 153.235 143.284 190.162 1.00 23.42  ? 687  SER A C   1 
ATOM 4155 O O   . SER A 1 687  ? 154.355 143.211 190.678 1.00 24.53  ? 687  SER A O   1 
ATOM 4156 C CB  . SER A 1 687  ? 151.441 142.153 191.491 1.00 18.67  ? 687  SER A CB  1 
ATOM 4157 O OG  . SER A 1 687  ? 150.395 142.332 192.428 1.00 25.48  ? 687  SER A OG  1 
ATOM 4158 N N   . LYS A 1 688  ? 153.047 143.180 188.847 1.00 17.64  ? 688  LYS A N   1 
ATOM 4159 C CA  . LYS A 1 688  ? 154.162 143.105 187.913 1.00 12.97  ? 688  LYS A CA  1 
ATOM 4160 C C   . LYS A 1 688  ? 154.881 144.436 187.745 1.00 11.15  ? 688  LYS A C   1 
ATOM 4161 O O   . LYS A 1 688  ? 155.910 144.481 187.064 1.00 14.94  ? 688  LYS A O   1 
ATOM 4162 C CB  . LYS A 1 688  ? 153.672 142.604 186.553 1.00 20.28  ? 688  LYS A CB  1 
ATOM 4163 C CG  . LYS A 1 688  ? 153.169 141.171 186.574 1.00 22.12  ? 688  LYS A CG  1 
ATOM 4164 C CD  . LYS A 1 688  ? 152.706 140.712 185.204 1.00 24.09  ? 688  LYS A CD  1 
ATOM 4165 C CE  . LYS A 1 688  ? 152.291 139.251 185.236 1.00 21.02  ? 688  LYS A CE  1 
ATOM 4166 N NZ  . LYS A 1 688  ? 151.077 139.033 186.063 1.00 25.65  ? 688  LYS A NZ  1 
ATOM 4167 N N   . GLY A 1 689  ? 154.370 145.511 188.340 1.00 10.74  ? 689  GLY A N   1 
ATOM 4168 C CA  . GLY A 1 689  ? 154.964 146.822 188.201 1.00 9.20   ? 689  GLY A CA  1 
ATOM 4169 C C   . GLY A 1 689  ? 154.442 147.638 187.045 1.00 7.30   ? 689  GLY A C   1 
ATOM 4170 O O   . GLY A 1 689  ? 154.993 148.709 186.766 1.00 6.31   ? 689  GLY A O   1 
ATOM 4171 N N   . ILE A 1 690  ? 153.396 147.174 186.370 1.00 7.23   ? 690  ILE A N   1 
ATOM 4172 C CA  . ILE A 1 690  ? 152.859 147.843 185.192 1.00 8.83   ? 690  ILE A CA  1 
ATOM 4173 C C   . ILE A 1 690  ? 151.944 148.966 185.663 1.00 8.04   ? 690  ILE A C   1 
ATOM 4174 O O   . ILE A 1 690  ? 150.912 148.720 186.292 1.00 17.59  ? 690  ILE A O   1 
ATOM 4175 C CB  . ILE A 1 690  ? 152.116 146.858 184.282 1.00 5.83   ? 690  ILE A CB  1 
ATOM 4176 C CG1 . ILE A 1 690  ? 153.082 145.798 183.751 1.00 6.92   ? 690  ILE A CG1 1 
ATOM 4177 C CG2 . ILE A 1 690  ? 151.437 147.589 183.142 1.00 10.90  ? 690  ILE A CG2 1 
ATOM 4178 C CD1 . ILE A 1 690  ? 152.401 144.647 183.062 1.00 12.36  ? 690  ILE A CD1 1 
ATOM 4179 N N   . LYS A 1 691  ? 152.325 150.203 185.360 1.00 12.40  ? 691  LYS A N   1 
ATOM 4180 C CA  . LYS A 1 691  ? 151.549 151.382 185.718 1.00 11.76  ? 691  LYS A CA  1 
ATOM 4181 C C   . LYS A 1 691  ? 150.980 152.090 184.498 1.00 13.32  ? 691  LYS A C   1 
ATOM 4182 O O   . LYS A 1 691  ? 150.263 153.083 184.649 1.00 18.11  ? 691  LYS A O   1 
ATOM 4183 C CB  . LYS A 1 691  ? 152.425 152.341 186.528 1.00 7.54   ? 691  LYS A CB  1 
ATOM 4184 C CG  . LYS A 1 691  ? 152.907 151.732 187.834 1.00 9.27   ? 691  LYS A CG  1 
ATOM 4185 C CD  . LYS A 1 691  ? 153.912 152.576 188.530 1.00 7.65   ? 691  LYS A CD  1 
ATOM 4186 C CE  . LYS A 1 691  ? 154.014 152.257 190.006 1.00 9.46   ? 691  LYS A CE  1 
ATOM 4187 N NZ  . LYS A 1 691  ? 155.193 151.419 190.300 1.00 16.15  ? 691  LYS A NZ  1 
ATOM 4188 N N   . ASN A 1 692  ? 151.289 151.601 183.299 1.00 5.28   ? 692  ASN A N   1 
ATOM 4189 C CA  . ASN A 1 692  ? 150.755 152.118 182.048 1.00 1.43   ? 692  ASN A CA  1 
ATOM 4190 C C   . ASN A 1 692  ? 150.144 150.956 181.280 1.00 4.18   ? 692  ASN A C   1 
ATOM 4191 O O   . ASN A 1 692  ? 150.797 149.926 181.092 1.00 10.62  ? 692  ASN A O   1 
ATOM 4192 C CB  . ASN A 1 692  ? 151.856 152.791 181.216 1.00 1.59   ? 692  ASN A CB  1 
ATOM 4193 C CG  . ASN A 1 692  ? 151.312 153.521 180.003 1.00 10.43  ? 692  ASN A CG  1 
ATOM 4194 O OD1 . ASN A 1 692  ? 150.113 153.517 179.750 1.00 22.53  ? 692  ASN A OD1 1 
ATOM 4195 N ND2 . ASN A 1 692  ? 152.198 154.122 179.226 1.00 9.07   ? 692  ASN A ND2 1 
ATOM 4196 N N   . LEU A 1 693  ? 148.898 151.118 180.841 1.00 0.00   ? 693  LEU A N   1 
ATOM 4197 C CA  . LEU A 1 693  ? 148.223 150.066 180.096 1.00 4.88   ? 693  LEU A CA  1 
ATOM 4198 C C   . LEU A 1 693  ? 147.057 150.670 179.329 1.00 13.57  ? 693  LEU A C   1 
ATOM 4199 O O   . LEU A 1 693  ? 146.520 151.714 179.705 1.00 21.20  ? 693  LEU A O   1 
ATOM 4200 C CB  . LEU A 1 693  ? 147.731 148.949 181.020 1.00 6.25   ? 693  LEU A CB  1 
ATOM 4201 C CG  . LEU A 1 693  ? 147.621 147.572 180.371 1.00 10.39  ? 693  LEU A CG  1 
ATOM 4202 C CD1 . LEU A 1 693  ? 148.939 147.191 179.734 1.00 11.56  ? 693  LEU A CD1 1 
ATOM 4203 C CD2 . LEU A 1 693  ? 147.186 146.543 181.374 1.00 12.41  ? 693  LEU A CD2 1 
ATOM 4204 N N   . LEU A 1 694  ? 146.669 149.995 178.251 1.00 10.67  ? 694  LEU A N   1 
ATOM 4205 C CA  . LEU A 1 694  ? 145.516 150.389 177.453 1.00 10.25  ? 694  LEU A CA  1 
ATOM 4206 C C   . LEU A 1 694  ? 144.329 149.504 177.805 1.00 11.13  ? 694  LEU A C   1 
ATOM 4207 O O   . LEU A 1 694  ? 144.495 148.309 178.070 1.00 13.67  ? 694  LEU A O   1 
ATOM 4208 C CB  . LEU A 1 694  ? 145.817 150.296 175.956 1.00 10.47  ? 694  LEU A CB  1 
ATOM 4209 C CG  . LEU A 1 694  ? 146.903 151.219 175.398 1.00 11.67  ? 694  LEU A CG  1 
ATOM 4210 C CD1 . LEU A 1 694  ? 147.264 150.823 173.975 1.00 8.74   ? 694  LEU A CD1 1 
ATOM 4211 C CD2 . LEU A 1 694  ? 146.458 152.669 175.453 1.00 16.64  ? 694  LEU A CD2 1 
ATOM 4212 N N   . LYS A 1 695  ? 143.137 150.095 177.807 1.00 11.70  ? 695  LYS A N   1 
ATOM 4213 C CA  . LYS A 1 695  ? 141.934 149.361 178.159 1.00 11.43  ? 695  LYS A CA  1 
ATOM 4214 C C   . LYS A 1 695  ? 141.650 148.279 177.120 1.00 19.02  ? 695  LYS A C   1 
ATOM 4215 O O   . LYS A 1 695  ? 141.935 148.457 175.934 1.00 25.31  ? 695  LYS A O   1 
ATOM 4216 C CB  . LYS A 1 695  ? 140.744 150.311 178.257 1.00 16.73  ? 695  LYS A CB  1 
ATOM 4217 C CG  . LYS A 1 695  ? 140.801 151.270 179.432 1.00 24.14  ? 695  LYS A CG  1 
ATOM 4218 C CD  . LYS A 1 695  ? 139.661 152.273 179.377 1.00 23.23  ? 695  LYS A CD  1 
ATOM 4219 C CE  . LYS A 1 695  ? 138.324 151.615 179.671 1.00 20.97  ? 695  LYS A CE  1 
ATOM 4220 N NZ  . LYS A 1 695  ? 137.225 152.617 179.729 1.00 22.59  ? 695  LYS A NZ  1 
ATOM 4221 N N   . PRO A 1 696  ? 141.116 147.137 177.545 1.00 21.67  ? 696  PRO A N   1 
ATOM 4222 C CA  . PRO A 1 696  ? 140.700 146.111 176.585 1.00 19.96  ? 696  PRO A CA  1 
ATOM 4223 C C   . PRO A 1 696  ? 139.763 146.683 175.534 1.00 25.63  ? 696  PRO A C   1 
ATOM 4224 O O   . PRO A 1 696  ? 138.878 147.485 175.836 1.00 23.59  ? 696  PRO A O   1 
ATOM 4225 C CB  . PRO A 1 696  ? 139.988 145.083 177.469 1.00 20.00  ? 696  PRO A CB  1 
ATOM 4226 C CG  . PRO A 1 696  ? 140.607 145.275 178.861 1.00 23.81  ? 696  PRO A CG  1 
ATOM 4227 C CD  . PRO A 1 696  ? 141.440 146.538 178.851 1.00 23.25  ? 696  PRO A CD  1 
ATOM 4228 N N   . GLY A 1 697  ? 139.971 146.264 174.290 1.00 21.67  ? 697  GLY A N   1 
ATOM 4229 C CA  . GLY A 1 697  ? 139.185 146.805 173.203 1.00 19.75  ? 697  GLY A CA  1 
ATOM 4230 C C   . GLY A 1 697  ? 139.533 148.224 172.824 1.00 17.22  ? 697  GLY A C   1 
ATOM 4231 O O   . GLY A 1 697  ? 138.694 148.925 172.254 1.00 25.01  ? 697  GLY A O   1 
ATOM 4232 N N   . TRP A 1 698  ? 140.752 148.674 173.136 1.00 10.21  ? 698  TRP A N   1 
ATOM 4233 C CA  . TRP A 1 698  ? 141.162 150.020 172.749 1.00 13.53  ? 698  TRP A CA  1 
ATOM 4234 C C   . TRP A 1 698  ? 141.165 150.185 171.237 1.00 19.67  ? 698  TRP A C   1 
ATOM 4235 O O   . TRP A 1 698  ? 140.918 151.287 170.732 1.00 25.03  ? 698  TRP A O   1 
ATOM 4236 C CB  . TRP A 1 698  ? 142.544 150.334 173.322 1.00 12.92  ? 698  TRP A CB  1 
ATOM 4237 C CG  . TRP A 1 698  ? 143.587 149.313 172.985 1.00 14.63  ? 698  TRP A CG  1 
ATOM 4238 C CD1 . TRP A 1 698  ? 143.846 148.154 173.654 1.00 13.59  ? 698  TRP A CD1 1 
ATOM 4239 C CD2 . TRP A 1 698  ? 144.521 149.366 171.899 1.00 17.54  ? 698  TRP A CD2 1 
ATOM 4240 N NE1 . TRP A 1 698  ? 144.876 147.478 173.051 1.00 12.42  ? 698  TRP A NE1 1 
ATOM 4241 C CE2 . TRP A 1 698  ? 145.309 148.201 171.971 1.00 15.71  ? 698  TRP A CE2 1 
ATOM 4242 C CE3 . TRP A 1 698  ? 144.764 150.282 170.873 1.00 18.14  ? 698  TRP A CE3 1 
ATOM 4243 C CZ2 . TRP A 1 698  ? 146.323 147.930 171.057 1.00 17.03  ? 698  TRP A CZ2 1 
ATOM 4244 C CZ3 . TRP A 1 698  ? 145.770 150.011 169.966 1.00 12.20  ? 698  TRP A CZ3 1 
ATOM 4245 C CH2 . TRP A 1 698  ? 146.537 148.846 170.064 1.00 10.80  ? 698  TRP A CH2 1 
ATOM 4246 N N   . GLN A 1 699  ? 141.447 149.108 170.502 1.00 15.79  ? 699  GLN A N   1 
ATOM 4247 C CA  . GLN A 1 699  ? 141.353 149.154 169.047 1.00 14.79  ? 699  GLN A CA  1 
ATOM 4248 C C   . GLN A 1 699  ? 139.920 149.410 168.598 1.00 18.74  ? 699  GLN A C   1 
ATOM 4249 O O   . GLN A 1 699  ? 139.680 150.208 167.685 1.00 23.57  ? 699  GLN A O   1 
ATOM 4250 C CB  . GLN A 1 699  ? 141.877 147.849 168.451 1.00 14.40  ? 699  GLN A CB  1 
ATOM 4251 C CG  . GLN A 1 699  ? 143.302 147.515 168.849 1.00 12.86  ? 699  GLN A CG  1 
ATOM 4252 C CD  . GLN A 1 699  ? 143.760 146.178 168.305 1.00 17.42  ? 699  GLN A CD  1 
ATOM 4253 O OE1 . GLN A 1 699  ? 142.951 145.281 168.070 1.00 21.33  ? 699  GLN A OE1 1 
ATOM 4254 N NE2 . GLN A 1 699  ? 145.064 146.038 168.099 1.00 20.54  ? 699  GLN A NE2 1 
ATOM 4255 N N   . GLY A 1 700  ? 138.958 148.751 169.235 1.00 19.74  ? 700  GLY A N   1 
ATOM 4256 C CA  . GLY A 1 700  ? 137.568 148.931 168.848 1.00 22.76  ? 700  GLY A CA  1 
ATOM 4257 C C   . GLY A 1 700  ? 137.300 148.304 167.495 1.00 24.67  ? 700  GLY A C   1 
ATOM 4258 O O   . GLY A 1 700  ? 137.665 147.152 167.235 1.00 21.66  ? 700  GLY A O   1 
ATOM 4259 N N   . GLU A 1 701  ? 136.649 149.064 166.620 1.00 27.71  ? 701  GLU A N   1 
ATOM 4260 C CA  . GLU A 1 701  ? 136.360 148.619 165.265 1.00 28.47  ? 701  GLU A CA  1 
ATOM 4261 C C   . GLU A 1 701  ? 137.419 149.056 164.263 1.00 27.37  ? 701  GLU A C   1 
ATOM 4262 O O   . GLU A 1 701  ? 137.276 148.772 163.069 1.00 28.77  ? 701  GLU A O   1 
ATOM 4263 C CB  . GLU A 1 701  ? 134.989 149.141 164.818 1.00 24.98  ? 701  GLU A CB  1 
ATOM 4264 C CG  . GLU A 1 701  ? 133.888 149.020 165.866 1.00 26.59  ? 701  GLU A CG  1 
ATOM 4265 C CD  . GLU A 1 701  ? 133.648 147.593 166.328 1.00 33.62  ? 701  GLU A CD  1 
ATOM 4266 O OE1 . GLU A 1 701  ? 133.111 147.415 167.441 1.00 32.54  ? 701  GLU A OE1 1 
ATOM 4267 O OE2 . GLU A 1 701  ? 133.976 146.649 165.578 1.00 29.57  ? 701  GLU A OE2 1 
ATOM 4268 N N   . ALA A 1 702  ? 138.469 149.737 164.715 1.00 16.59  ? 702  ALA A N   1 
ATOM 4269 C CA  . ALA A 1 702  ? 139.479 150.257 163.806 1.00 10.84  ? 702  ALA A CA  1 
ATOM 4270 C C   . ALA A 1 702  ? 140.221 149.126 163.107 1.00 18.80  ? 702  ALA A C   1 
ATOM 4271 O O   . ALA A 1 702  ? 140.603 148.131 163.729 1.00 19.60  ? 702  ALA A O   1 
ATOM 4272 C CB  . ALA A 1 702  ? 140.470 151.139 164.563 1.00 7.68   ? 702  ALA A CB  1 
ATOM 4273 N N   . LYS A 1 703  ? 140.420 149.285 161.800 1.00 18.36  ? 703  LYS A N   1 
ATOM 4274 C CA  . LYS A 1 703  ? 141.204 148.345 161.012 1.00 10.79  ? 703  LYS A CA  1 
ATOM 4275 C C   . LYS A 1 703  ? 142.642 148.796 160.814 1.00 7.25   ? 703  LYS A C   1 
ATOM 4276 O O   . LYS A 1 703  ? 143.516 147.956 160.579 1.00 11.41  ? 703  LYS A O   1 
ATOM 4277 C CB  . LYS A 1 703  ? 140.550 148.124 159.643 1.00 8.83   ? 703  LYS A CB  1 
ATOM 4278 C CG  . LYS A 1 703  ? 139.165 147.505 159.710 1.00 15.11  ? 703  LYS A CG  1 
ATOM 4279 C CD  . LYS A 1 703  ? 139.206 146.102 160.292 1.00 12.91  ? 703  LYS A CD  1 
ATOM 4280 C CE  . LYS A 1 703  ? 139.850 145.123 159.327 1.00 16.51  ? 703  LYS A CE  1 
ATOM 4281 N NZ  . LYS A 1 703  ? 139.828 143.732 159.853 1.00 14.95  ? 703  LYS A NZ  1 
ATOM 4282 N N   . ILE A 1 704  ? 142.902 150.097 160.899 1.00 0.00   ? 704  ILE A N   1 
ATOM 4283 C CA  . ILE A 1 704  ? 144.249 150.651 160.857 1.00 0.89   ? 704  ILE A CA  1 
ATOM 4284 C C   . ILE A 1 704  ? 144.446 151.506 162.099 1.00 5.18   ? 704  ILE A C   1 
ATOM 4285 O O   . ILE A 1 704  ? 143.640 152.401 162.373 1.00 9.99   ? 704  ILE A O   1 
ATOM 4286 C CB  . ILE A 1 704  ? 144.488 151.484 159.584 1.00 6.14   ? 704  ILE A CB  1 
ATOM 4287 C CG1 . ILE A 1 704  ? 144.377 150.610 158.336 1.00 9.25   ? 704  ILE A CG1 1 
ATOM 4288 C CG2 . ILE A 1 704  ? 145.844 152.165 159.641 1.00 0.00   ? 704  ILE A CG2 1 
ATOM 4289 C CD1 . ILE A 1 704  ? 144.343 151.396 157.046 1.00 3.21   ? 704  ILE A CD1 1 
ATOM 4290 N N   . ILE A 1 705  ? 145.511 151.233 162.846 1.00 5.52   ? 705  ILE A N   1 
ATOM 4291 C CA  . ILE A 1 705  ? 145.884 152.032 164.007 1.00 4.23   ? 705  ILE A CA  1 
ATOM 4292 C C   . ILE A 1 705  ? 147.161 152.787 163.673 1.00 1.80   ? 705  ILE A C   1 
ATOM 4293 O O   . ILE A 1 705  ? 148.167 152.186 163.277 1.00 9.72   ? 705  ILE A O   1 
ATOM 4294 C CB  . ILE A 1 705  ? 146.055 151.181 165.275 1.00 3.44   ? 705  ILE A CB  1 
ATOM 4295 C CG1 . ILE A 1 705  ? 144.732 150.518 165.669 1.00 5.98   ? 705  ILE A CG1 1 
ATOM 4296 C CG2 . ILE A 1 705  ? 146.587 152.030 166.420 1.00 7.18   ? 705  ILE A CG2 1 
ATOM 4297 C CD1 . ILE A 1 705  ? 144.492 149.183 165.043 1.00 4.49   ? 705  ILE A CD1 1 
ATOM 4298 N N   . LEU A 1 706  ? 147.111 154.104 163.827 1.00 2.31   ? 706  LEU A N   1 
ATOM 4299 C CA  . LEU A 1 706  ? 148.242 154.983 163.586 1.00 2.46   ? 706  LEU A CA  1 
ATOM 4300 C C   . LEU A 1 706  ? 148.908 155.306 164.914 1.00 8.94   ? 706  LEU A C   1 
ATOM 4301 O O   . LEU A 1 706  ? 148.226 155.658 165.880 1.00 22.26  ? 706  LEU A O   1 
ATOM 4302 C CB  . LEU A 1 706  ? 147.777 156.262 162.896 1.00 10.63  ? 706  LEU A CB  1 
ATOM 4303 C CG  . LEU A 1 706  ? 146.726 156.144 161.801 1.00 14.57  ? 706  LEU A CG  1 
ATOM 4304 C CD1 . LEU A 1 706  ? 146.229 157.518 161.414 1.00 15.96  ? 706  LEU A CD1 1 
ATOM 4305 C CD2 . LEU A 1 706  ? 147.290 155.420 160.596 1.00 12.49  ? 706  LEU A CD2 1 
ATOM 4306 N N   . THR A 1 707  ? 150.232 155.185 164.966 1.00 0.82   ? 707  THR A N   1 
ATOM 4307 C CA  . THR A 1 707  ? 150.941 155.407 166.216 1.00 4.13   ? 707  THR A CA  1 
ATOM 4308 C C   . THR A 1 707  ? 152.346 155.908 165.920 1.00 2.74   ? 707  THR A C   1 
ATOM 4309 O O   . THR A 1 707  ? 152.847 155.792 164.800 1.00 10.23  ? 707  THR A O   1 
ATOM 4310 C CB  . THR A 1 707  ? 150.991 154.134 167.068 1.00 5.36   ? 707  THR A CB  1 
ATOM 4311 O OG1 . THR A 1 707  ? 151.407 154.464 168.395 1.00 10.88  ? 707  THR A OG1 1 
ATOM 4312 C CG2 . THR A 1 707  ? 151.969 153.140 166.482 1.00 3.90   ? 707  THR A CG2 1 
ATOM 4313 N N   . THR A 1 708  ? 152.966 156.487 166.940 1.00 1.29   ? 708  THR A N   1 
ATOM 4314 C CA  . THR A 1 708  ? 154.290 157.081 166.838 1.00 0.00   ? 708  THR A CA  1 
ATOM 4315 C C   . THR A 1 708  ? 155.335 156.097 167.356 1.00 3.28   ? 708  THR A C   1 
ATOM 4316 O O   . THR A 1 708  ? 155.026 155.157 168.092 1.00 7.79   ? 708  THR A O   1 
ATOM 4317 C CB  . THR A 1 708  ? 154.341 158.398 167.627 1.00 7.01   ? 708  THR A CB  1 
ATOM 4318 O OG1 . THR A 1 708  ? 153.161 159.160 167.350 1.00 17.00  ? 708  THR A OG1 1 
ATOM 4319 C CG2 . THR A 1 708  ? 155.549 159.239 167.235 1.00 7.95   ? 708  THR A CG2 1 
ATOM 4320 N N   . TYR A 1 709  ? 156.585 156.308 166.935 1.00 6.46   ? 709  TYR A N   1 
ATOM 4321 C CA  . TYR A 1 709  ? 157.681 155.481 167.429 1.00 3.90   ? 709  TYR A CA  1 
ATOM 4322 C C   . TYR A 1 709  ? 157.850 155.643 168.935 1.00 4.02   ? 709  TYR A C   1 
ATOM 4323 O O   . TYR A 1 709  ? 158.101 154.664 169.650 1.00 3.46   ? 709  TYR A O   1 
ATOM 4324 C CB  . TYR A 1 709  ? 158.974 155.840 166.700 1.00 4.49   ? 709  TYR A CB  1 
ATOM 4325 C CG  . TYR A 1 709  ? 159.151 155.141 165.372 1.00 6.38   ? 709  TYR A CG  1 
ATOM 4326 C CD1 . TYR A 1 709  ? 159.576 153.822 165.306 1.00 11.40  ? 709  TYR A CD1 1 
ATOM 4327 C CD2 . TYR A 1 709  ? 158.893 155.804 164.182 1.00 6.63   ? 709  TYR A CD2 1 
ATOM 4328 C CE1 . TYR A 1 709  ? 159.739 153.185 164.095 1.00 10.51  ? 709  TYR A CE1 1 
ATOM 4329 C CE2 . TYR A 1 709  ? 159.052 155.174 162.966 1.00 4.88   ? 709  TYR A CE2 1 
ATOM 4330 C CZ  . TYR A 1 709  ? 159.476 153.866 162.928 1.00 10.83  ? 709  TYR A CZ  1 
ATOM 4331 O OH  . TYR A 1 709  ? 159.638 153.238 161.718 1.00 17.47  ? 709  TYR A OH  1 
ATOM 4332 N N   . GLU A 1 710  ? 157.717 156.875 169.432 1.00 6.48   ? 710  GLU A N   1 
ATOM 4333 C CA  . GLU A 1 710  ? 157.718 157.101 170.873 1.00 0.02   ? 710  GLU A CA  1 
ATOM 4334 C C   . GLU A 1 710  ? 156.541 156.399 171.534 1.00 4.72   ? 710  GLU A C   1 
ATOM 4335 O O   . GLU A 1 710  ? 156.680 155.820 172.616 1.00 14.48  ? 710  GLU A O   1 
ATOM 4336 C CB  . GLU A 1 710  ? 157.678 158.599 171.170 1.00 3.97   ? 710  GLU A CB  1 
ATOM 4337 C CG  . GLU A 1 710  ? 158.659 159.416 170.356 1.00 13.47  ? 710  GLU A CG  1 
ATOM 4338 C CD  . GLU A 1 710  ? 160.083 158.927 170.505 1.00 17.66  ? 710  GLU A CD  1 
ATOM 4339 O OE1 . GLU A 1 710  ? 160.702 158.571 169.480 1.00 12.55  ? 710  GLU A OE1 1 
ATOM 4340 O OE2 . GLU A 1 710  ? 160.585 158.901 171.648 1.00 15.77  ? 710  GLU A OE2 1 
ATOM 4341 N N   . THR A 1 711  ? 155.370 156.448 170.899 1.00 4.30   ? 711  THR A N   1 
ATOM 4342 C CA  . THR A 1 711  ? 154.224 155.698 171.396 1.00 2.79   ? 711  THR A CA  1 
ATOM 4343 C C   . THR A 1 711  ? 154.447 154.197 171.285 1.00 5.38   ? 711  THR A C   1 
ATOM 4344 O O   . THR A 1 711  ? 153.962 153.434 172.128 1.00 10.28  ? 711  THR A O   1 
ATOM 4345 C CB  . THR A 1 711  ? 152.967 156.103 170.633 1.00 4.84   ? 711  THR A CB  1 
ATOM 4346 O OG1 . THR A 1 711  ? 152.896 157.532 170.551 1.00 12.98  ? 711  THR A OG1 1 
ATOM 4347 C CG2 . THR A 1 711  ? 151.739 155.577 171.327 1.00 0.19   ? 711  THR A CG2 1 
ATOM 4348 N N   . LEU A 1 712  ? 155.163 153.757 170.249 1.00 7.16   ? 712  LEU A N   1 
ATOM 4349 C CA  . LEU A 1 712  ? 155.515 152.347 170.134 1.00 3.39   ? 712  LEU A CA  1 
ATOM 4350 C C   . LEU A 1 712  ? 156.372 151.902 171.311 1.00 3.83   ? 712  LEU A C   1 
ATOM 4351 O O   . LEU A 1 712  ? 156.171 150.814 171.861 1.00 14.53  ? 712  LEU A O   1 
ATOM 4352 C CB  . LEU A 1 712  ? 156.242 152.102 168.812 1.00 5.96   ? 712  LEU A CB  1 
ATOM 4353 C CG  . LEU A 1 712  ? 156.577 150.668 168.408 1.00 4.39   ? 712  LEU A CG  1 
ATOM 4354 C CD1 . LEU A 1 712  ? 155.316 149.892 168.064 1.00 7.60   ? 712  LEU A CD1 1 
ATOM 4355 C CD2 . LEU A 1 712  ? 157.540 150.678 167.236 1.00 1.44   ? 712  LEU A CD2 1 
ATOM 4356 N N   . ARG A 1 713  ? 157.339 152.733 171.708 1.00 0.00   ? 713  ARG A N   1 
ATOM 4357 C CA  . ARG A 1 713  ? 158.166 152.409 172.866 1.00 0.63   ? 713  ARG A CA  1 
ATOM 4358 C C   . ARG A 1 713  ? 157.366 152.476 174.161 1.00 2.39   ? 713  ARG A C   1 
ATOM 4359 O O   . ARG A 1 713  ? 157.519 151.616 175.036 1.00 0.12   ? 713  ARG A O   1 
ATOM 4360 C CB  . ARG A 1 713  ? 159.363 153.354 172.935 1.00 3.12   ? 713  ARG A CB  1 
ATOM 4361 C CG  . ARG A 1 713  ? 160.445 152.911 173.903 1.00 5.99   ? 713  ARG A CG  1 
ATOM 4362 C CD  . ARG A 1 713  ? 161.317 154.077 174.333 1.00 5.93   ? 713  ARG A CD  1 
ATOM 4363 N NE  . ARG A 1 713  ? 160.522 155.236 174.720 1.00 6.90   ? 713  ARG A NE  1 
ATOM 4364 C CZ  . ARG A 1 713  ? 160.590 156.423 174.133 1.00 8.92   ? 713  ARG A CZ  1 
ATOM 4365 N NH1 . ARG A 1 713  ? 161.414 156.648 173.124 1.00 9.33   ? 713  ARG A NH1 1 
ATOM 4366 N NH2 . ARG A 1 713  ? 159.811 157.408 174.570 1.00 3.78   ? 713  ARG A NH2 1 
ATOM 4367 N N   . ASP A 1 714  ? 156.511 153.491 174.303 1.00 11.20  ? 714  ASP A N   1 
ATOM 4368 C CA  . ASP A 1 714  ? 155.802 153.707 175.560 1.00 5.67   ? 714  ASP A CA  1 
ATOM 4369 C C   . ASP A 1 714  ? 154.693 152.688 175.773 1.00 4.82   ? 714  ASP A C   1 
ATOM 4370 O O   . ASP A 1 714  ? 154.364 152.363 176.919 1.00 10.88  ? 714  ASP A O   1 
ATOM 4371 C CB  . ASP A 1 714  ? 155.225 155.122 175.600 1.00 1.45   ? 714  ASP A CB  1 
ATOM 4372 C CG  . ASP A 1 714  ? 156.281 156.177 175.854 1.00 12.21  ? 714  ASP A CG  1 
ATOM 4373 O OD1 . ASP A 1 714  ? 156.030 157.358 175.541 1.00 21.24  ? 714  ASP A OD1 1 
ATOM 4374 O OD2 . ASP A 1 714  ? 157.365 155.826 176.361 1.00 9.60   ? 714  ASP A OD2 1 
ATOM 4375 N N   . GLN A 1 715  ? 154.098 152.183 174.694 1.00 5.02   ? 715  GLN A N   1 
ATOM 4376 C CA  . GLN A 1 715  ? 153.001 151.228 174.775 1.00 0.00   ? 715  GLN A CA  1 
ATOM 4377 C C   . GLN A 1 715  ? 153.392 149.869 174.203 1.00 1.66   ? 715  GLN A C   1 
ATOM 4378 O O   . GLN A 1 715  ? 152.547 149.154 173.661 1.00 9.16   ? 715  GLN A O   1 
ATOM 4379 C CB  . GLN A 1 715  ? 151.766 151.771 174.060 1.00 2.99   ? 715  GLN A CB  1 
ATOM 4380 C CG  . GLN A 1 715  ? 151.369 153.176 174.480 1.00 2.48   ? 715  GLN A CG  1 
ATOM 4381 C CD  . GLN A 1 715  ? 150.639 153.210 175.807 1.00 12.41  ? 715  GLN A CD  1 
ATOM 4382 O OE1 . GLN A 1 715  ? 150.125 152.194 176.274 1.00 15.14  ? 715  GLN A OE1 1 
ATOM 4383 N NE2 . GLN A 1 715  ? 150.592 154.383 176.425 1.00 10.92  ? 715  GLN A NE2 1 
ATOM 4384 N N   . GLU A 1 716  ? 154.670 149.503 174.325 1.00 0.00   ? 716  GLU A N   1 
ATOM 4385 C CA  . GLU A 1 716  ? 155.144 148.243 173.760 1.00 3.34   ? 716  GLU A CA  1 
ATOM 4386 C C   . GLU A 1 716  ? 154.388 147.053 174.332 1.00 8.77   ? 716  GLU A C   1 
ATOM 4387 O O   . GLU A 1 716  ? 154.071 146.107 173.606 1.00 14.07  ? 716  GLU A O   1 
ATOM 4388 C CB  . GLU A 1 716  ? 156.642 148.081 174.010 1.00 1.02   ? 716  GLU A CB  1 
ATOM 4389 C CG  . GLU A 1 716  ? 157.242 146.831 173.394 1.00 5.85   ? 716  GLU A CG  1 
ATOM 4390 C CD  . GLU A 1 716  ? 158.735 146.732 173.626 1.00 14.39  ? 716  GLU A CD  1 
ATOM 4391 O OE1 . GLU A 1 716  ? 159.296 147.630 174.284 1.00 18.17  ? 716  GLU A OE1 1 
ATOM 4392 O OE2 . GLU A 1 716  ? 159.354 145.762 173.147 1.00 16.08  ? 716  GLU A OE2 1 
ATOM 4393 N N   . PHE A 1 717  ? 154.097 147.077 175.633 1.00 3.29   ? 717  PHE A N   1 
ATOM 4394 C CA  . PHE A 1 717  ? 153.426 145.945 176.263 1.00 0.00   ? 717  PHE A CA  1 
ATOM 4395 C C   . PHE A 1 717  ? 152.033 145.746 175.676 1.00 2.45   ? 717  PHE A C   1 
ATOM 4396 O O   . PHE A 1 717  ? 151.691 144.651 175.212 1.00 12.12  ? 717  PHE A O   1 
ATOM 4397 C CB  . PHE A 1 717  ? 153.364 146.166 177.776 1.00 3.03   ? 717  PHE A CB  1 
ATOM 4398 C CG  . PHE A 1 717  ? 152.797 145.007 178.548 1.00 11.12  ? 717  PHE A CG  1 
ATOM 4399 C CD1 . PHE A 1 717  ? 151.470 144.996 178.937 1.00 7.58   ? 717  PHE A CD1 1 
ATOM 4400 C CD2 . PHE A 1 717  ? 153.603 143.943 178.914 1.00 10.37  ? 717  PHE A CD2 1 
ATOM 4401 C CE1 . PHE A 1 717  ? 150.952 143.938 179.657 1.00 5.19   ? 717  PHE A CE1 1 
ATOM 4402 C CE2 . PHE A 1 717  ? 153.091 142.883 179.634 1.00 7.90   ? 717  PHE A CE2 1 
ATOM 4403 C CZ  . PHE A 1 717  ? 151.764 142.880 180.005 1.00 5.64   ? 717  PHE A CZ  1 
ATOM 4404 N N   . SER A 1 718  ? 151.229 146.811 175.651 1.00 7.37   ? 718  SER A N   1 
ATOM 4405 C CA  . SER A 1 718  ? 149.864 146.708 175.143 1.00 5.33   ? 718  SER A CA  1 
ATOM 4406 C C   . SER A 1 718  ? 149.843 146.415 173.649 1.00 5.99   ? 718  SER A C   1 
ATOM 4407 O O   . SER A 1 718  ? 149.035 145.604 173.182 1.00 17.81  ? 718  SER A O   1 
ATOM 4408 C CB  . SER A 1 718  ? 149.097 147.995 175.440 1.00 11.35  ? 718  SER A CB  1 
ATOM 4409 O OG  . SER A 1 718  ? 148.957 148.199 176.831 1.00 10.39  ? 718  SER A OG  1 
ATOM 4410 N N   . LEU A 1 719  ? 150.716 147.071 172.880 1.00 2.30   ? 719  LEU A N   1 
ATOM 4411 C CA  . LEU A 1 719  ? 150.750 146.841 171.440 1.00 4.72   ? 719  LEU A CA  1 
ATOM 4412 C C   . LEU A 1 719  ? 151.211 145.425 171.119 1.00 9.19   ? 719  LEU A C   1 
ATOM 4413 O O   . LEU A 1 719  ? 150.762 144.827 170.134 1.00 14.22  ? 719  LEU A O   1 
ATOM 4414 C CB  . LEU A 1 719  ? 151.659 147.869 170.763 1.00 2.20   ? 719  LEU A CB  1 
ATOM 4415 C CG  . LEU A 1 719  ? 151.189 149.327 170.767 1.00 7.42   ? 719  LEU A CG  1 
ATOM 4416 C CD1 . LEU A 1 719  ? 152.357 150.275 170.545 1.00 4.24   ? 719  LEU A CD1 1 
ATOM 4417 C CD2 . LEU A 1 719  ? 150.110 149.556 169.723 1.00 6.06   ? 719  LEU A CD2 1 
ATOM 4418 N N   . ALA A 1 720  ? 152.101 144.871 171.940 1.00 2.96   ? 720  ALA A N   1 
ATOM 4419 C CA  . ALA A 1 720  ? 152.640 143.541 171.710 1.00 0.41   ? 720  ALA A CA  1 
ATOM 4420 C C   . ALA A 1 720  ? 151.750 142.432 172.250 1.00 8.72   ? 720  ALA A C   1 
ATOM 4421 O O   . ALA A 1 720  ? 151.942 141.272 171.872 1.00 16.53  ? 720  ALA A O   1 
ATOM 4422 C CB  . ALA A 1 720  ? 154.033 143.430 172.328 1.00 0.00   ? 720  ALA A CB  1 
ATOM 4423 N N   . ARG A 1 721  ? 150.796 142.746 173.129 1.00 3.67   ? 721  ARG A N   1 
ATOM 4424 C CA  . ARG A 1 721  ? 149.826 141.729 173.525 1.00 6.06   ? 721  ARG A CA  1 
ATOM 4425 C C   . ARG A 1 721  ? 148.908 141.359 172.364 1.00 15.60  ? 721  ARG A C   1 
ATOM 4426 O O   . ARG A 1 721  ? 148.583 140.182 172.174 1.00 20.68  ? 721  ARG A O   1 
ATOM 4427 C CB  . ARG A 1 721  ? 149.008 142.208 174.722 1.00 4.86   ? 721  ARG A CB  1 
ATOM 4428 C CG  . ARG A 1 721  ? 149.833 142.472 175.963 1.00 13.66  ? 721  ARG A CG  1 
ATOM 4429 C CD  . ARG A 1 721  ? 149.110 142.075 177.229 1.00 14.77  ? 721  ARG A CD  1 
ATOM 4430 N NE  . ARG A 1 721  ? 148.132 143.077 177.633 1.00 15.85  ? 721  ARG A NE  1 
ATOM 4431 C CZ  . ARG A 1 721  ? 147.241 142.903 178.599 1.00 19.82  ? 721  ARG A CZ  1 
ATOM 4432 N NH1 . ARG A 1 721  ? 147.189 141.780 179.296 1.00 17.91  ? 721  ARG A NH1 1 
ATOM 4433 N NH2 . ARG A 1 721  ? 146.385 143.882 178.876 1.00 16.35  ? 721  ARG A NH2 1 
ATOM 4434 N N   . GLN A 1 722  ? 148.490 142.345 171.567 1.00 14.63  ? 722  GLN A N   1 
ATOM 4435 C CA  . GLN A 1 722  ? 147.475 142.078 170.530 1.00 9.49   ? 722  GLN A CA  1 
ATOM 4436 C C   . GLN A 1 722  ? 148.055 141.463 169.254 1.00 8.68   ? 722  GLN A C   1 
ATOM 4437 O O   . GLN A 1 722  ? 149.290 141.672 169.003 1.00 4.10   ? 722  GLN A O   1 
ATOM 4438 C CB  . GLN A 1 722  ? 146.757 143.366 170.169 1.00 9.98   ? 722  GLN A CB  1 
ATOM 4439 C CG  . GLN A 1 722  ? 145.979 143.987 171.323 1.00 18.02  ? 722  GLN A CG  1 
ATOM 4440 C CD  . GLN A 1 722  ? 144.673 143.259 171.593 1.00 23.32  ? 722  GLN A CD  1 
ATOM 4441 O OE1 . GLN A 1 722  ? 144.510 142.098 171.221 1.00 20.67  ? 722  GLN A OE1 1 
ATOM 4442 N NE2 . GLN A 1 722  ? 143.728 143.948 172.223 1.00 18.01  ? 722  GLN A NE2 1 
ATOM 4443 N N   . PRO A 1 723  ? 147.253 140.755 168.425 1.00 21.42  ? 723  PRO A N   1 
ATOM 4444 C CA  . PRO A 1 723  ? 147.814 140.333 167.125 1.00 11.22  ? 723  PRO A CA  1 
ATOM 4445 C C   . PRO A 1 723  ? 147.687 141.401 166.063 1.00 8.75   ? 723  PRO A C   1 
ATOM 4446 O O   . PRO A 1 723  ? 146.740 142.169 166.066 1.00 12.06  ? 723  PRO A O   1 
ATOM 4447 C CB  . PRO A 1 723  ? 147.035 139.049 166.816 1.00 13.12  ? 723  PRO A CB  1 
ATOM 4448 C CG  . PRO A 1 723  ? 146.498 139.628 167.461 1.00 21.03  ? 723  PRO A CG  1 
ATOM 4449 C CD  . PRO A 1 723  ? 145.911 140.262 168.166 1.00 20.32  ? 723  PRO A CD  1 
ATOM 4450 N N   . TRP A 1 724  ? 148.619 141.416 165.101 1.00 7.50   ? 724  TRP A N   1 
ATOM 4451 C CA  . TRP A 1 724  ? 148.550 142.369 164.000 1.00 4.83   ? 724  TRP A CA  1 
ATOM 4452 C C   . TRP A 1 724  ? 148.709 141.630 162.683 1.00 8.81   ? 724  TRP A C   1 
ATOM 4453 O O   . TRP A 1 724  ? 149.317 140.559 162.614 1.00 14.23  ? 724  TRP A O   1 
ATOM 4454 C CB  . TRP A 1 724  ? 149.624 143.453 164.114 1.00 0.00   ? 724  TRP A CB  1 
ATOM 4455 C CG  . TRP A 1 724  ? 149.592 144.198 165.399 1.00 5.42   ? 724  TRP A CG  1 
ATOM 4456 C CD1 . TRP A 1 724  ? 150.297 143.917 166.525 1.00 3.71   ? 724  TRP A CD1 1 
ATOM 4457 C CD2 . TRP A 1 724  ? 148.797 145.348 165.699 1.00 10.69  ? 724  TRP A CD2 1 
ATOM 4458 N NE1 . TRP A 1 724  ? 150.007 144.829 167.509 1.00 2.75   ? 724  TRP A NE1 1 
ATOM 4459 C CE2 . TRP A 1 724  ? 149.083 145.718 167.026 1.00 3.01   ? 724  TRP A CE2 1 
ATOM 4460 C CE3 . TRP A 1 724  ? 147.873 146.103 164.973 1.00 9.40   ? 724  TRP A CE3 1 
ATOM 4461 C CZ2 . TRP A 1 724  ? 148.479 146.809 167.641 1.00 5.88   ? 724  TRP A CZ2 1 
ATOM 4462 C CZ3 . TRP A 1 724  ? 147.276 147.183 165.583 1.00 4.15   ? 724  TRP A CZ3 1 
ATOM 4463 C CH2 . TRP A 1 724  ? 147.580 147.527 166.904 1.00 6.19   ? 724  TRP A CH2 1 
ATOM 4464 N N   . SER A 1 725  ? 148.152 142.224 161.632 1.00 2.11   ? 725  SER A N   1 
ATOM 4465 C CA  . SER A 1 725  ? 148.269 141.666 160.290 1.00 1.66   ? 725  SER A CA  1 
ATOM 4466 C C   . SER A 1 725  ? 149.450 142.269 159.536 1.00 2.61   ? 725  SER A C   1 
ATOM 4467 O O   . SER A 1 725  ? 150.352 141.547 159.104 1.00 14.58  ? 725  SER A O   1 
ATOM 4468 C CB  . SER A 1 725  ? 146.972 141.890 159.510 1.00 4.14   ? 725  SER A CB  1 
ATOM 4469 O OG  . SER A 1 725  ? 145.886 141.197 160.096 1.00 9.11   ? 725  SER A OG  1 
ATOM 4470 N N   . ILE A 1 726  ? 149.448 143.587 159.359 1.00 0.00   ? 726  ILE A N   1 
ATOM 4471 C CA  . ILE A 1 726  ? 150.522 144.290 158.671 1.00 0.00   ? 726  ILE A CA  1 
ATOM 4472 C C   . ILE A 1 726  ? 151.016 145.403 159.581 1.00 0.00   ? 726  ILE A C   1 
ATOM 4473 O O   . ILE A 1 726  ? 150.214 146.185 160.102 1.00 7.89   ? 726  ILE A O   1 
ATOM 4474 C CB  . ILE A 1 726  ? 150.068 144.867 157.316 1.00 1.93   ? 726  ILE A CB  1 
ATOM 4475 C CG1 . ILE A 1 726  ? 149.747 143.744 156.334 1.00 0.00   ? 726  ILE A CG1 1 
ATOM 4476 C CG2 . ILE A 1 726  ? 151.153 145.751 156.725 1.00 2.51   ? 726  ILE A CG2 1 
ATOM 4477 C CD1 . ILE A 1 726  ? 148.560 144.033 155.447 1.00 2.19   ? 726  ILE A CD1 1 
ATOM 4478 N N   . MET A 1 727  ? 152.328 145.468 159.780 1.00 0.00   ? 727  MET A N   1 
ATOM 4479 C CA  . MET A 1 727  ? 152.958 146.532 160.552 1.00 0.00   ? 727  MET A CA  1 
ATOM 4480 C C   . MET A 1 727  ? 153.856 147.320 159.610 1.00 0.00   ? 727  MET A C   1 
ATOM 4481 O O   . MET A 1 727  ? 154.855 146.793 159.111 1.00 9.91   ? 727  MET A O   1 
ATOM 4482 C CB  . MET A 1 727  ? 153.752 145.970 161.730 1.00 0.00   ? 727  MET A CB  1 
ATOM 4483 C CG  . MET A 1 727  ? 154.723 146.963 162.346 1.00 0.04   ? 727  MET A CG  1 
ATOM 4484 S SD  . MET A 1 727  ? 155.332 146.439 163.957 1.00 12.47  ? 727  MET A SD  1 
ATOM 4485 C CE  . MET A 1 727  ? 156.043 147.964 164.565 1.00 1.48   ? 727  MET A CE  1 
ATOM 4486 N N   . VAL A 1 728  ? 153.500 148.574 159.362 1.00 0.00   ? 728  VAL A N   1 
ATOM 4487 C CA  . VAL A 1 728  ? 154.262 149.446 158.478 1.00 2.06   ? 728  VAL A CA  1 
ATOM 4488 C C   . VAL A 1 728  ? 155.045 150.422 159.342 1.00 5.79   ? 728  VAL A C   1 
ATOM 4489 O O   . VAL A 1 728  ? 154.459 151.194 160.109 1.00 9.03   ? 728  VAL A O   1 
ATOM 4490 C CB  . VAL A 1 728  ? 153.347 150.187 157.491 1.00 1.75   ? 728  VAL A CB  1 
ATOM 4491 C CG1 . VAL A 1 728  ? 154.075 151.371 156.873 1.00 0.00   ? 728  VAL A CG1 1 
ATOM 4492 C CG2 . VAL A 1 728  ? 152.852 149.238 156.415 1.00 2.25   ? 728  VAL A CG2 1 
ATOM 4493 N N   . CYS A 1 729  ? 156.369 150.382 159.231 1.00 0.80   ? 729  CYS A N   1 
ATOM 4494 C CA  . CYS A 1 729  ? 157.248 151.303 159.946 1.00 0.00   ? 729  CYS A CA  1 
ATOM 4495 C C   . CYS A 1 729  ? 157.735 152.352 158.954 1.00 4.57   ? 729  CYS A C   1 
ATOM 4496 O O   . CYS A 1 729  ? 158.775 152.196 158.315 1.00 12.48  ? 729  CYS A O   1 
ATOM 4497 C CB  . CYS A 1 729  ? 158.403 150.561 160.606 1.00 3.71   ? 729  CYS A CB  1 
ATOM 4498 S SG  . CYS A 1 729  ? 157.899 149.444 161.923 1.00 21.61  ? 729  CYS A SG  1 
ATOM 4499 N N   . ASP A 1 730  ? 156.965 153.428 158.823 1.00 6.32   ? 730  ASP A N   1 
ATOM 4500 C CA  . ASP A 1 730  ? 157.358 154.530 157.958 1.00 13.58  ? 730  ASP A CA  1 
ATOM 4501 C C   . ASP A 1 730  ? 158.595 155.219 158.519 1.00 14.13  ? 730  ASP A C   1 
ATOM 4502 O O   . ASP A 1 730  ? 158.728 155.398 159.732 1.00 14.72  ? 730  ASP A O   1 
ATOM 4503 C CB  . ASP A 1 730  ? 156.210 155.526 157.816 1.00 7.97   ? 730  ASP A CB  1 
ATOM 4504 C CG  . ASP A 1 730  ? 156.382 156.447 156.629 1.00 20.25  ? 730  ASP A CG  1 
ATOM 4505 O OD1 . ASP A 1 730  ? 157.313 156.221 155.829 1.00 18.77  ? 730  ASP A OD1 1 
ATOM 4506 O OD2 . ASP A 1 730  ? 155.586 157.400 156.497 1.00 29.38  ? 730  ASP A OD2 1 
ATOM 4507 N N   . GLU A 1 731  ? 159.501 155.609 157.624 1.00 10.62  ? 731  GLU A N   1 
ATOM 4508 C CA  . GLU A 1 731  ? 160.827 156.097 157.995 1.00 13.81  ? 731  GLU A CA  1 
ATOM 4509 C C   . GLU A 1 731  ? 161.530 155.087 158.900 1.00 16.30  ? 731  GLU A C   1 
ATOM 4510 O O   . GLU A 1 731  ? 161.820 155.342 160.068 1.00 17.39  ? 731  GLU A O   1 
ATOM 4511 C CB  . GLU A 1 731  ? 160.756 157.475 158.651 1.00 14.57  ? 731  GLU A CB  1 
ATOM 4512 C CG  . GLU A 1 731  ? 159.941 158.469 157.866 1.00 19.07  ? 731  GLU A CG  1 
ATOM 4513 C CD  . GLU A 1 731  ? 160.615 158.899 156.579 1.00 26.62  ? 731  GLU A CD  1 
ATOM 4514 O OE1 . GLU A 1 731  ? 161.440 159.835 156.622 1.00 30.08  ? 731  GLU A OE1 1 
ATOM 4515 O OE2 . GLU A 1 731  ? 160.318 158.303 155.522 1.00 20.83  ? 731  GLU A OE2 1 
ATOM 4516 N N   . ALA A 1 732  ? 161.799 153.917 158.323 1.00 12.84  ? 732  ALA A N   1 
ATOM 4517 C CA  . ALA A 1 732  ? 162.397 152.811 159.057 1.00 10.03  ? 732  ALA A CA  1 
ATOM 4518 C C   . ALA A 1 732  ? 163.820 153.093 159.521 1.00 14.09  ? 732  ALA A C   1 
ATOM 4519 O O   . ALA A 1 732  ? 164.417 152.221 160.159 1.00 20.62  ? 732  ALA A O   1 
ATOM 4520 C CB  . ALA A 1 732  ? 162.375 151.545 158.200 1.00 15.08  ? 732  ALA A CB  1 
ATOM 4521 N N   . GLN A 1 733  ? 164.384 154.267 159.228 1.00 7.12   ? 733  GLN A N   1 
ATOM 4522 C CA  . GLN A 1 733  ? 165.685 154.600 159.793 1.00 12.81  ? 733  GLN A CA  1 
ATOM 4523 C C   . GLN A 1 733  ? 165.601 154.952 161.272 1.00 15.48  ? 733  GLN A C   1 
ATOM 4524 O O   . GLN A 1 733  ? 166.642 155.173 161.897 1.00 21.10  ? 733  GLN A O   1 
ATOM 4525 C CB  . GLN A 1 733  ? 166.342 155.746 159.014 1.00 15.38  ? 733  GLN A CB  1 
ATOM 4526 C CG  . GLN A 1 733  ? 165.687 157.108 159.174 1.00 17.54  ? 733  GLN A CG  1 
ATOM 4527 C CD  . GLN A 1 733  ? 164.524 157.312 158.227 1.00 21.19  ? 733  GLN A CD  1 
ATOM 4528 O OE1 . GLN A 1 733  ? 163.999 156.359 157.657 1.00 26.03  ? 733  GLN A OE1 1 
ATOM 4529 N NE2 . GLN A 1 733  ? 164.118 158.563 158.050 1.00 15.30  ? 733  GLN A NE2 1 
ATOM 4530 N N   . LYS A 1 734  ? 164.394 155.027 161.841 1.00 14.00  ? 734  LYS A N   1 
ATOM 4531 C CA  . LYS A 1 734  ? 164.271 155.150 163.289 1.00 12.41  ? 734  LYS A CA  1 
ATOM 4532 C C   . LYS A 1 734  ? 164.690 153.868 163.997 1.00 14.19  ? 734  LYS A C   1 
ATOM 4533 O O   . LYS A 1 734  ? 165.196 153.921 165.123 1.00 13.28  ? 734  LYS A O   1 
ATOM 4534 C CB  . LYS A 1 734  ? 162.837 155.514 163.673 1.00 9.28   ? 734  LYS A CB  1 
ATOM 4535 C CG  . LYS A 1 734  ? 162.264 156.701 162.921 1.00 12.25  ? 734  LYS A CG  1 
ATOM 4536 C CD  . LYS A 1 734  ? 163.115 157.942 163.111 1.00 14.94  ? 734  LYS A CD  1 
ATOM 4537 C CE  . LYS A 1 734  ? 162.250 159.187 163.211 1.00 19.36  ? 734  LYS A CE  1 
ATOM 4538 N NZ  . LYS A 1 734  ? 161.355 159.143 164.400 1.00 16.26  ? 734  LYS A NZ  1 
ATOM 4539 N N   . ILE A 1 735  ? 164.492 152.716 163.359 1.00 13.77  ? 735  ILE A N   1 
ATOM 4540 C CA  . ILE A 1 735  ? 164.798 151.427 163.970 1.00 10.03  ? 735  ILE A CA  1 
ATOM 4541 C C   . ILE A 1 735  ? 166.069 150.852 163.362 1.00 8.61   ? 735  ILE A C   1 
ATOM 4542 O O   . ILE A 1 735  ? 166.271 149.633 163.354 1.00 14.59  ? 735  ILE A O   1 
ATOM 4543 C CB  . ILE A 1 735  ? 163.620 150.446 163.822 1.00 6.47   ? 735  ILE A CB  1 
ATOM 4544 C CG1 . ILE A 1 735  ? 163.333 150.164 162.345 1.00 8.28   ? 735  ILE A CG1 1 
ATOM 4545 C CG2 . ILE A 1 735  ? 162.388 150.985 164.527 1.00 10.62  ? 735  ILE A CG2 1 
ATOM 4546 C CD1 . ILE A 1 735  ? 162.352 149.041 162.116 1.00 3.92   ? 735  ILE A CD1 1 
ATOM 4547 N N   . LYS A 1 736  ? 166.938 151.726 162.850 1.00 8.51   ? 736  LYS A N   1 
ATOM 4548 C CA  . LYS A 1 736  ? 168.202 151.265 162.288 1.00 11.91  ? 736  LYS A CA  1 
ATOM 4549 C C   . LYS A 1 736  ? 169.191 150.835 163.362 1.00 14.07  ? 736  LYS A C   1 
ATOM 4550 O O   . LYS A 1 736  ? 170.148 150.117 163.053 1.00 14.34  ? 736  LYS A O   1 
ATOM 4551 C CB  . LYS A 1 736  ? 168.827 152.359 161.423 1.00 13.13  ? 736  LYS A CB  1 
ATOM 4552 C CG  . LYS A 1 736  ? 169.296 153.571 162.205 1.00 12.90  ? 736  LYS A CG  1 
ATOM 4553 C CD  . LYS A 1 736  ? 169.886 154.625 161.285 1.00 16.34  ? 736  LYS A CD  1 
ATOM 4554 C CE  . LYS A 1 736  ? 170.316 155.854 162.064 1.00 21.28  ? 736  LYS A CE  1 
ATOM 4555 N NZ  . LYS A 1 736  ? 171.457 155.557 162.970 1.00 22.00  ? 736  LYS A NZ  1 
ATOM 4556 N N   . ASN A 1 737  ? 168.991 151.259 164.608 1.00 17.57  ? 737  ASN A N   1 
ATOM 4557 C CA  . ASN A 1 737  ? 169.878 150.878 165.698 1.00 11.10  ? 737  ASN A CA  1 
ATOM 4558 C C   . ASN A 1 737  ? 169.358 149.599 166.337 1.00 11.05  ? 737  ASN A C   1 
ATOM 4559 O O   . ASN A 1 737  ? 168.254 149.608 166.894 1.00 17.19  ? 737  ASN A O   1 
ATOM 4560 C CB  . ASN A 1 737  ? 169.961 151.989 166.733 1.00 12.12  ? 737  ASN A CB  1 
ATOM 4561 C CG  . ASN A 1 737  ? 171.001 151.723 167.812 1.00 16.95  ? 737  ASN A CG  1 
ATOM 4562 O OD1 . ASN A 1 737  ? 171.442 150.592 168.012 1.00 19.70  ? 737  ASN A OD1 1 
ATOM 4563 N ND2 . ASN A 1 737  ? 171.394 152.776 168.517 1.00 17.85  ? 737  ASN A ND2 1 
ATOM 4564 N N   . PRO A 1 738  ? 170.099 148.491 166.278 1.00 15.65  ? 738  PRO A N   1 
ATOM 4565 C CA  . PRO A 1 738  ? 169.566 147.224 166.810 1.00 14.39  ? 738  PRO A CA  1 
ATOM 4566 C C   . PRO A 1 738  ? 169.240 147.261 168.294 1.00 15.53  ? 738  PRO A C   1 
ATOM 4567 O O   . PRO A 1 738  ? 168.295 146.587 168.723 1.00 14.82  ? 738  PRO A O   1 
ATOM 4568 C CB  . PRO A 1 738  ? 170.678 146.208 166.511 1.00 17.42  ? 738  PRO A CB  1 
ATOM 4569 C CG  . PRO A 1 738  ? 171.604 146.859 165.561 1.00 17.18  ? 738  PRO A CG  1 
ATOM 4570 C CD  . PRO A 1 738  ? 171.378 148.330 165.567 1.00 17.17  ? 738  PRO A CD  1 
ATOM 4571 N N   . ALA A 1 739  ? 169.987 148.021 169.092 1.00 14.57  ? 739  ALA A N   1 
ATOM 4572 C CA  . ALA A 1 739  ? 169.850 147.992 170.542 1.00 12.67  ? 739  ALA A CA  1 
ATOM 4573 C C   . ALA A 1 739  ? 168.962 149.100 171.094 1.00 11.31  ? 739  ALA A C   1 
ATOM 4574 O O   . ALA A 1 739  ? 168.852 149.231 172.316 1.00 16.95  ? 739  ALA A O   1 
ATOM 4575 C CB  . ALA A 1 739  ? 171.228 148.066 171.203 1.00 21.44  ? 739  ALA A CB  1 
ATOM 4576 N N   . ALA A 1 740  ? 168.336 149.899 170.237 1.00 12.72  ? 740  ALA A N   1 
ATOM 4577 C CA  . ALA A 1 740  ? 167.450 150.949 170.715 1.00 7.34   ? 740  ALA A CA  1 
ATOM 4578 C C   . ALA A 1 740  ? 166.149 150.356 171.247 1.00 12.11  ? 740  ALA A C   1 
ATOM 4579 O O   . ALA A 1 740  ? 165.651 149.345 170.746 1.00 13.39  ? 740  ALA A O   1 
ATOM 4580 C CB  . ALA A 1 740  ? 167.156 151.948 169.598 1.00 7.71   ? 740  ALA A CB  1 
ATOM 4581 N N   . LEU A 1 741  ? 165.597 151.002 172.278 1.00 4.38   ? 741  LEU A N   1 
ATOM 4582 C CA  . LEU A 1 741  ? 164.333 150.540 172.845 1.00 4.20   ? 741  LEU A CA  1 
ATOM 4583 C C   . LEU A 1 741  ? 163.194 150.666 171.842 1.00 4.99   ? 741  LEU A C   1 
ATOM 4584 O O   . LEU A 1 741  ? 162.249 149.871 171.867 1.00 15.10  ? 741  LEU A O   1 
ATOM 4585 C CB  . LEU A 1 741  ? 164.004 151.309 174.126 1.00 12.21  ? 741  LEU A CB  1 
ATOM 4586 C CG  . LEU A 1 741  ? 164.731 150.928 175.420 1.00 13.44  ? 741  LEU A CG  1 
ATOM 4587 C CD1 . LEU A 1 741  ? 166.182 151.340 175.416 1.00 14.08  ? 741  LEU A CD1 1 
ATOM 4588 C CD2 . LEU A 1 741  ? 164.021 151.536 176.609 1.00 4.98   ? 741  LEU A CD2 1 
ATOM 4589 N N   . ILE A 1 742  ? 163.260 151.658 170.955 1.00 5.02   ? 742  ILE A N   1 
ATOM 4590 C CA  . ILE A 1 742  ? 162.258 151.762 169.900 1.00 2.50   ? 742  ILE A CA  1 
ATOM 4591 C C   . ILE A 1 742  ? 162.381 150.590 168.934 1.00 5.54   ? 742  ILE A C   1 
ATOM 4592 O O   . ILE A 1 742  ? 161.375 150.043 168.468 1.00 10.51  ? 742  ILE A O   1 
ATOM 4593 C CB  . ILE A 1 742  ? 162.379 153.119 169.184 1.00 9.13   ? 742  ILE A CB  1 
ATOM 4594 C CG1 . ILE A 1 742  ? 162.092 154.260 170.161 1.00 12.91  ? 742  ILE A CG1 1 
ATOM 4595 C CG2 . ILE A 1 742  ? 161.428 153.187 168.017 1.00 6.03   ? 742  ILE A CG2 1 
ATOM 4596 C CD1 . ILE A 1 742  ? 162.434 155.628 169.622 1.00 10.21  ? 742  ILE A CD1 1 
ATOM 4597 N N   . THR A 1 743  ? 163.613 150.178 168.625 1.00 4.35   ? 743  THR A N   1 
ATOM 4598 C CA  . THR A 1 743  ? 163.813 149.001 167.784 1.00 1.37   ? 743  THR A CA  1 
ATOM 4599 C C   . THR A 1 743  ? 163.305 147.739 168.471 1.00 6.87   ? 743  THR A C   1 
ATOM 4600 O O   . THR A 1 743  ? 162.694 146.875 167.830 1.00 11.74  ? 743  THR A O   1 
ATOM 4601 C CB  . THR A 1 743  ? 165.291 148.856 167.430 1.00 5.99   ? 743  THR A CB  1 
ATOM 4602 O OG1 . THR A 1 743  ? 165.731 150.020 166.722 1.00 19.49  ? 743  THR A OG1 1 
ATOM 4603 C CG2 . THR A 1 743  ? 165.515 147.635 166.555 1.00 7.41   ? 743  THR A CG2 1 
ATOM 4604 N N   . HIS A 1 744  ? 163.557 147.612 169.777 1.00 8.76   ? 744  HIS A N   1 
ATOM 4605 C CA  . HIS A 1 744  ? 163.040 146.470 170.523 1.00 3.11   ? 744  HIS A CA  1 
ATOM 4606 C C   . HIS A 1 744  ? 161.519 146.460 170.533 1.00 1.51   ? 744  HIS A C   1 
ATOM 4607 O O   . HIS A 1 744  ? 160.901 145.394 170.470 1.00 6.68   ? 744  HIS A O   1 
ATOM 4608 C CB  . HIS A 1 744  ? 163.581 146.476 171.953 1.00 9.94   ? 744  HIS A CB  1 
ATOM 4609 C CG  . HIS A 1 744  ? 165.074 146.433 172.042 1.00 9.60   ? 744  HIS A CG  1 
ATOM 4610 N ND1 . HIS A 1 744  ? 165.744 146.423 173.245 1.00 16.26  ? 744  HIS A ND1 1 
ATOM 4611 C CD2 . HIS A 1 744  ? 166.026 146.376 171.081 1.00 10.49  ? 744  HIS A CD2 1 
ATOM 4612 C CE1 . HIS A 1 744  ? 167.045 146.375 173.022 1.00 16.72  ? 744  HIS A CE1 1 
ATOM 4613 N NE2 . HIS A 1 744  ? 167.242 146.345 171.717 1.00 14.30  ? 744  HIS A NE2 1 
ATOM 4614 N N   . ALA A 1 745  ? 160.897 147.636 170.628 1.00 2.22   ? 745  ALA A N   1 
ATOM 4615 C CA  . ALA A 1 745  ? 159.441 147.706 170.582 1.00 0.00   ? 745  ALA A CA  1 
ATOM 4616 C C   . ALA A 1 745  ? 158.911 147.339 169.204 1.00 7.26   ? 745  ALA A C   1 
ATOM 4617 O O   . ALA A 1 745  ? 157.881 146.664 169.088 1.00 15.21  ? 745  ALA A O   1 
ATOM 4618 C CB  . ALA A 1 745  ? 158.968 149.100 170.988 1.00 1.32   ? 745  ALA A CB  1 
ATOM 4619 N N   . ALA A 1 746  ? 159.594 147.784 168.149 1.00 7.56   ? 746  ALA A N   1 
ATOM 4620 C CA  . ALA A 1 746  ? 159.172 147.449 166.793 1.00 0.00   ? 746  ALA A CA  1 
ATOM 4621 C C   . ALA A 1 746  ? 159.279 145.953 166.533 1.00 3.23   ? 746  ALA A C   1 
ATOM 4622 O O   . ALA A 1 746  ? 158.391 145.360 165.911 1.00 4.17   ? 746  ALA A O   1 
ATOM 4623 C CB  . ALA A 1 746  ? 160.000 148.233 165.777 1.00 1.57   ? 746  ALA A CB  1 
ATOM 4624 N N   . ASN A 1 747  ? 160.360 145.326 166.999 1.00 5.34   ? 747  ASN A N   1 
ATOM 4625 C CA  . ASN A 1 747  ? 160.512 143.886 166.831 1.00 0.46   ? 747  ASN A CA  1 
ATOM 4626 C C   . ASN A 1 747  ? 159.579 143.101 167.745 1.00 6.32   ? 747  ASN A C   1 
ATOM 4627 O O   . ASN A 1 747  ? 159.146 142.001 167.383 1.00 10.79  ? 747  ASN A O   1 
ATOM 4628 C CB  . ASN A 1 747  ? 161.962 143.475 167.087 1.00 0.60   ? 747  ASN A CB  1 
ATOM 4629 C CG  . ASN A 1 747  ? 162.897 143.927 165.986 1.00 4.26   ? 747  ASN A CG  1 
ATOM 4630 O OD1 . ASN A 1 747  ? 162.461 144.300 164.899 1.00 10.58  ? 747  ASN A OD1 1 
ATOM 4631 N ND2 . ASN A 1 747  ? 164.192 143.894 166.262 1.00 8.71   ? 747  ASN A ND2 1 
ATOM 4632 N N   . ALA A 1 748  ? 159.263 143.646 168.922 1.00 7.34   ? 748  ALA A N   1 
ATOM 4633 C CA  . ALA A 1 748  ? 158.429 142.937 169.887 1.00 0.04   ? 748  ALA A CA  1 
ATOM 4634 C C   . ALA A 1 748  ? 157.017 142.732 169.361 1.00 3.22   ? 748  ALA A C   1 
ATOM 4635 O O   . ALA A 1 748  ? 156.416 141.675 169.581 1.00 9.38   ? 748  ALA A O   1 
ATOM 4636 C CB  . ALA A 1 748  ? 158.396 143.699 171.206 1.00 3.82   ? 748  ALA A CB  1 
ATOM 4637 N N   . VAL A 1 749  ? 156.465 143.740 168.683 1.00 1.15   ? 749  VAL A N   1 
ATOM 4638 C CA  . VAL A 1 749  ? 155.141 143.603 168.095 1.00 0.45   ? 749  VAL A CA  1 
ATOM 4639 C C   . VAL A 1 749  ? 155.172 142.484 167.068 1.00 5.20   ? 749  VAL A C   1 
ATOM 4640 O O   . VAL A 1 749  ? 156.044 142.447 166.193 1.00 10.27  ? 749  VAL A O   1 
ATOM 4641 C CB  . VAL A 1 749  ? 154.698 144.934 167.470 1.00 3.60   ? 749  VAL A CB  1 
ATOM 4642 C CG1 . VAL A 1 749  ? 153.373 144.775 166.765 1.00 7.49   ? 749  VAL A CG1 1 
ATOM 4643 C CG2 . VAL A 1 749  ? 154.615 146.016 168.535 1.00 6.40   ? 749  VAL A CG2 1 
ATOM 4644 N N   . GLN A 1 750  ? 154.233 141.550 167.183 1.00 8.78   ? 750  GLN A N   1 
ATOM 4645 C CA  . GLN A 1 750  ? 154.183 140.381 166.314 1.00 2.49   ? 750  GLN A CA  1 
ATOM 4646 C C   . GLN A 1 750  ? 153.108 140.601 165.258 1.00 6.39   ? 750  GLN A C   1 
ATOM 4647 O O   . GLN A 1 750  ? 151.914 140.637 165.573 1.00 9.71   ? 750  GLN A O   1 
ATOM 4648 C CB  . GLN A 1 750  ? 153.919 139.113 167.122 1.00 3.89   ? 750  GLN A CB  1 
ATOM 4649 C CG  . GLN A 1 750  ? 155.039 138.758 168.088 1.00 11.97  ? 750  GLN A CG  1 
ATOM 4650 C CD  . GLN A 1 750  ? 156.350 138.464 167.380 1.00 19.37  ? 750  GLN A CD  1 
ATOM 4651 O OE1 . GLN A 1 750  ? 157.300 139.244 167.456 1.00 15.40  ? 750  GLN A OE1 1 
ATOM 4652 N NE2 . GLN A 1 750  ? 156.406 137.334 166.686 1.00 19.19  ? 750  GLN A NE2 1 
ATOM 4653 N N   . ALA A 1 751  ? 153.535 140.738 164.005 1.00 7.04   ? 751  ALA A N   1 
ATOM 4654 C CA  . ALA A 1 751  ? 152.640 140.954 162.881 1.00 0.00   ? 751  ALA A CA  1 
ATOM 4655 C C   . ALA A 1 751  ? 152.924 139.921 161.803 1.00 3.47   ? 751  ALA A C   1 
ATOM 4656 O O   . ALA A 1 751  ? 154.042 139.413 161.687 1.00 14.28  ? 751  ALA A O   1 
ATOM 4657 C CB  . ALA A 1 751  ? 152.791 142.366 162.304 1.00 2.51   ? 751  ALA A CB  1 
ATOM 4658 N N   . ARG A 1 752  ? 151.891 139.608 161.017 1.00 6.96   ? 752  ARG A N   1 
ATOM 4659 C CA  . ARG A 1 752  ? 152.056 138.653 159.926 1.00 6.55   ? 752  ARG A CA  1 
ATOM 4660 C C   . ARG A 1 752  ? 153.026 139.178 158.875 1.00 6.83   ? 752  ARG A C   1 
ATOM 4661 O O   . ARG A 1 752  ? 153.880 138.434 158.380 1.00 15.68  ? 752  ARG A O   1 
ATOM 4662 C CB  . ARG A 1 752  ? 150.698 138.341 159.297 1.00 1.61   ? 752  ARG A CB  1 
ATOM 4663 C CG  . ARG A 1 752  ? 150.770 137.475 158.055 1.00 2.67   ? 752  ARG A CG  1 
ATOM 4664 C CD  . ARG A 1 752  ? 149.395 137.285 157.441 1.00 9.27   ? 752  ARG A CD  1 
ATOM 4665 N NE  . ARG A 1 752  ? 149.461 136.588 156.163 1.00 17.56  ? 752  ARG A NE  1 
ATOM 4666 C CZ  . ARG A 1 752  ? 148.404 136.270 155.429 1.00 14.70  ? 752  ARG A CZ  1 
ATOM 4667 N NH1 . ARG A 1 752  ? 147.176 136.569 155.819 1.00 11.44  ? 752  ARG A NH1 1 
ATOM 4668 N NH2 . ARG A 1 752  ? 148.584 135.637 154.273 1.00 8.69   ? 752  ARG A NH2 1 
ATOM 4669 N N   . PHE A 1 753  ? 152.912 140.455 158.525 1.00 0.00   ? 753  PHE A N   1 
ATOM 4670 C CA  . PHE A 1 753  ? 153.770 141.085 157.535 1.00 0.00   ? 753  PHE A CA  1 
ATOM 4671 C C   . PHE A 1 753  ? 154.262 142.410 158.091 1.00 0.00   ? 753  PHE A C   1 
ATOM 4672 O O   . PHE A 1 753  ? 153.493 143.152 158.704 1.00 2.12   ? 753  PHE A O   1 
ATOM 4673 C CB  . PHE A 1 753  ? 153.021 141.311 156.218 1.00 2.32   ? 753  PHE A CB  1 
ATOM 4674 C CG  . PHE A 1 753  ? 153.912 141.371 155.013 1.00 6.07   ? 753  PHE A CG  1 
ATOM 4675 C CD1 . PHE A 1 753  ? 153.925 142.490 154.199 1.00 0.00   ? 753  PHE A CD1 1 
ATOM 4676 C CD2 . PHE A 1 753  ? 154.734 140.306 154.692 1.00 3.73   ? 753  PHE A CD2 1 
ATOM 4677 C CE1 . PHE A 1 753  ? 154.742 142.547 153.092 1.00 2.52   ? 753  PHE A CE1 1 
ATOM 4678 C CE2 . PHE A 1 753  ? 155.552 140.357 153.584 1.00 4.85   ? 753  PHE A CE2 1 
ATOM 4679 C CZ  . PHE A 1 753  ? 155.556 141.478 152.784 1.00 7.05   ? 753  PHE A CZ  1 
ATOM 4680 N N   . LYS A 1 754  ? 155.542 142.704 157.883 1.00 0.00   ? 754  LYS A N   1 
ATOM 4681 C CA  . LYS A 1 754  ? 156.148 143.925 158.398 1.00 0.00   ? 754  LYS A CA  1 
ATOM 4682 C C   . LYS A 1 754  ? 156.841 144.656 157.261 1.00 0.00   ? 754  LYS A C   1 
ATOM 4683 O O   . LYS A 1 754  ? 157.773 144.122 156.653 1.00 5.31   ? 754  LYS A O   1 
ATOM 4684 C CB  . LYS A 1 754  ? 157.133 143.612 159.524 1.00 0.00   ? 754  LYS A CB  1 
ATOM 4685 C CG  . LYS A 1 754  ? 156.465 143.018 160.745 1.00 0.00   ? 754  LYS A CG  1 
ATOM 4686 C CD  . LYS A 1 754  ? 157.258 143.308 161.990 1.00 0.04   ? 754  LYS A CD  1 
ATOM 4687 C CE  . LYS A 1 754  ? 156.505 142.890 163.224 1.00 1.98   ? 754  LYS A CE  1 
ATOM 4688 N NZ  . LYS A 1 754  ? 157.281 141.922 164.043 1.00 6.01   ? 754  LYS A NZ  1 
ATOM 4689 N N   . VAL A 1 755  ? 156.403 145.879 156.989 1.00 3.96   ? 755  VAL A N   1 
ATOM 4690 C CA  . VAL A 1 755  ? 156.908 146.668 155.874 1.00 3.20   ? 755  VAL A CA  1 
ATOM 4691 C C   . VAL A 1 755  ? 157.771 147.786 156.439 1.00 4.98   ? 755  VAL A C   1 
ATOM 4692 O O   . VAL A 1 755  ? 157.297 148.609 157.230 1.00 7.69   ? 755  VAL A O   1 
ATOM 4693 C CB  . VAL A 1 755  ? 155.764 147.234 155.019 1.00 1.61   ? 755  VAL A CB  1 
ATOM 4694 C CG1 . VAL A 1 755  ? 156.318 148.089 153.896 1.00 1.97   ? 755  VAL A CG1 1 
ATOM 4695 C CG2 . VAL A 1 755  ? 154.903 146.108 154.472 1.00 0.53   ? 755  VAL A CG2 1 
ATOM 4696 N N   . ALA A 1 756  ? 159.037 147.811 156.038 1.00 7.28   ? 756  ALA A N   1 
ATOM 4697 C CA  . ALA A 1 756  ? 159.949 148.891 156.383 1.00 4.21   ? 756  ALA A CA  1 
ATOM 4698 C C   . ALA A 1 756  ? 159.984 149.875 155.221 1.00 8.33   ? 756  ALA A C   1 
ATOM 4699 O O   . ALA A 1 756  ? 160.320 149.497 154.094 1.00 12.14  ? 756  ALA A O   1 
ATOM 4700 C CB  . ALA A 1 756  ? 161.348 148.355 156.685 1.00 3.25   ? 756  ALA A CB  1 
ATOM 4701 N N   . CYS A 1 757  ? 159.630 151.127 155.493 1.00 9.18   ? 757  CYS A N   1 
ATOM 4702 C CA  . CYS A 1 757  ? 159.532 152.161 154.468 1.00 11.05  ? 757  CYS A CA  1 
ATOM 4703 C C   . CYS A 1 757  ? 160.535 153.258 154.788 1.00 12.99  ? 757  CYS A C   1 
ATOM 4704 O O   . CYS A 1 757  ? 160.326 154.041 155.719 1.00 17.35  ? 757  CYS A O   1 
ATOM 4705 C CB  . CYS A 1 757  ? 158.117 152.732 154.396 1.00 11.75  ? 757  CYS A CB  1 
ATOM 4706 S SG  . CYS A 1 757  ? 156.841 151.548 153.933 1.00 30.68  ? 757  CYS A SG  1 
ATOM 4707 N N   . THR A 1 758  ? 161.618 153.318 154.019 1.00 15.63  ? 758  THR A N   1 
ATOM 4708 C CA  . THR A 1 758  ? 162.583 154.396 154.165 1.00 20.19  ? 758  THR A CA  1 
ATOM 4709 C C   . THR A 1 758  ? 163.318 154.575 152.845 1.00 20.54  ? 758  THR A C   1 
ATOM 4710 O O   . THR A 1 758  ? 163.587 153.600 152.140 1.00 20.19  ? 758  THR A O   1 
ATOM 4711 C CB  . THR A 1 758  ? 163.570 154.125 155.311 1.00 17.23  ? 758  THR A CB  1 
ATOM 4712 O OG1 . THR A 1 758  ? 164.340 155.305 155.573 1.00 21.68  ? 758  THR A OG1 1 
ATOM 4713 C CG2 . THR A 1 758  ? 164.503 152.970 154.980 1.00 16.21  ? 758  THR A CG2 1 
ATOM 4714 N N   . GLY A 1 759  ? 163.610 155.831 152.503 1.00 21.88  ? 759  GLY A N   1 
ATOM 4715 C CA  . GLY A 1 759  ? 164.364 156.105 151.295 1.00 23.65  ? 759  GLY A CA  1 
ATOM 4716 C C   . GLY A 1 759  ? 165.842 155.813 151.418 1.00 26.42  ? 759  GLY A C   1 
ATOM 4717 O O   . GLY A 1 759  ? 166.511 155.613 150.399 1.00 28.69  ? 759  GLY A O   1 
ATOM 4718 N N   . THR A 1 760  ? 166.365 155.777 152.642 1.00 19.48  ? 760  THR A N   1 
ATOM 4719 C CA  . THR A 1 760  ? 167.783 155.531 152.903 1.00 22.69  ? 760  THR A CA  1 
ATOM 4720 C C   . THR A 1 760  ? 167.905 154.385 153.898 1.00 26.87  ? 760  THR A C   1 
ATOM 4721 O O   . THR A 1 760  ? 168.042 154.612 155.108 1.00 32.70  ? 760  THR A O   1 
ATOM 4722 C CB  . THR A 1 760  ? 168.479 156.785 153.435 1.00 25.65  ? 760  THR A CB  1 
ATOM 4723 O OG1 . THR A 1 760  ? 168.060 157.029 154.785 1.00 29.15  ? 760  THR A OG1 1 
ATOM 4724 C CG2 . THR A 1 760  ? 168.144 157.999 152.579 1.00 26.53  ? 760  THR A CG2 1 
ATOM 4725 N N   . PRO A 1 761  ? 167.835 153.136 153.427 1.00 21.91  ? 761  PRO A N   1 
ATOM 4726 C CA  . PRO A 1 761  ? 168.062 152.003 154.339 1.00 20.06  ? 761  PRO A CA  1 
ATOM 4727 C C   . PRO A 1 761  ? 169.404 152.059 155.041 1.00 21.52  ? 761  PRO A C   1 
ATOM 4728 O O   . PRO A 1 761  ? 169.499 151.672 156.212 1.00 24.95  ? 761  PRO A O   1 
ATOM 4729 C CB  . PRO A 1 761  ? 167.972 150.780 153.418 1.00 21.01  ? 761  PRO A CB  1 
ATOM 4730 C CG  . PRO A 1 761  ? 167.237 151.224 152.220 1.00 21.94  ? 761  PRO A CG  1 
ATOM 4731 C CD  . PRO A 1 761  ? 167.221 152.721 152.155 1.00 20.89  ? 761  PRO A CD  1 
ATOM 4732 N N   . VAL A 1 762  ? 170.444 152.528 154.360 1.00 25.48  ? 762  VAL A N   1 
ATOM 4733 C CA  . VAL A 1 762  ? 171.789 152.606 154.913 1.00 24.93  ? 762  VAL A CA  1 
ATOM 4734 C C   . VAL A 1 762  ? 172.152 154.075 155.058 1.00 30.16  ? 762  VAL A C   1 
ATOM 4735 O O   . VAL A 1 762  ? 172.219 154.805 154.061 1.00 34.85  ? 762  VAL A O   1 
ATOM 4736 C CB  . VAL A 1 762  ? 172.809 151.872 154.030 1.00 22.88  ? 762  VAL A CB  1 
ATOM 4737 C CG1 . VAL A 1 762  ? 174.209 152.034 154.591 1.00 24.64  ? 762  VAL A CG1 1 
ATOM 4738 C CG2 . VAL A 1 762  ? 172.442 150.402 153.912 1.00 24.86  ? 762  VAL A CG2 1 
ATOM 4739 N N   . GLU A 1 763  ? 172.382 154.508 156.295 1.00 26.30  ? 763  GLU A N   1 
ATOM 4740 C CA  . GLU A 1 763  ? 172.769 155.880 156.594 1.00 27.91  ? 763  GLU A CA  1 
ATOM 4741 C C   . GLU A 1 763  ? 174.221 155.995 157.028 1.00 32.02  ? 763  GLU A C   1 
ATOM 4742 O O   . GLU A 1 763  ? 174.949 156.864 156.538 1.00 36.64  ? 763  GLU A O   1 
ATOM 4743 C CB  . GLU A 1 763  ? 171.854 156.461 157.682 1.00 27.58  ? 763  GLU A CB  1 
ATOM 4744 C CG  . GLU A 1 763  ? 170.564 157.063 157.154 1.00 29.24  ? 763  GLU A CG  1 
ATOM 4745 C CD  . GLU A 1 763  ? 169.962 158.076 158.108 1.00 30.55  ? 763  GLU A CD  1 
ATOM 4746 O OE1 . GLU A 1 763  ? 169.725 159.226 157.683 1.00 29.91  ? 763  GLU A OE1 1 
ATOM 4747 O OE2 . GLU A 1 763  ? 169.728 157.723 159.282 1.00 26.17  ? 763  GLU A OE2 1 
ATOM 4748 N N   . ASN A 1 764  ? 174.662 155.136 157.943 1.00 32.37  ? 764  ASN A N   1 
ATOM 4749 C CA  . ASN A 1 764  ? 176.042 155.129 158.410 1.00 27.88  ? 764  ASN A CA  1 
ATOM 4750 C C   . ASN A 1 764  ? 176.762 153.834 158.073 1.00 28.63  ? 764  ASN A C   1 
ATOM 4751 O O   . ASN A 1 764  ? 177.854 153.871 157.493 1.00 33.32  ? 764  ASN A O   1 
ATOM 4752 C CB  . ASN A 1 764  ? 176.085 155.373 159.927 1.00 30.37  ? 764  ASN A CB  1 
ATOM 4753 C CG  . ASN A 1 764  ? 175.591 156.755 160.309 1.00 36.31  ? 764  ASN A CG  1 
ATOM 4754 O OD1 . ASN A 1 764  ? 174.510 156.905 160.877 1.00 37.29  ? 764  ASN A OD1 1 
ATOM 4755 N ND2 . ASN A 1 764  ? 176.384 157.773 159.997 1.00 35.54  ? 764  ASN A ND2 1 
ATOM 4756 N N   . THR A 1 765  ? 176.185 152.687 158.424 1.00 25.74  ? 765  THR A N   1 
ATOM 4757 C CA  . THR A 1 765  ? 176.792 151.391 158.160 1.00 26.19  ? 765  THR A CA  1 
ATOM 4758 C C   . THR A 1 765  ? 175.734 150.445 157.611 1.00 23.01  ? 765  THR A C   1 
ATOM 4759 O O   . THR A 1 765  ? 174.543 150.764 157.569 1.00 24.20  ? 765  THR A O   1 
ATOM 4760 C CB  . THR A 1 765  ? 177.427 150.787 159.422 1.00 27.56  ? 765  THR A CB  1 
ATOM 4761 O OG1 . THR A 1 765  ? 176.417 150.590 160.420 1.00 25.83  ? 765  THR A OG1 1 
ATOM 4762 C CG2 . THR A 1 765  ? 178.517 151.696 159.976 1.00 29.66  ? 765  THR A CG2 1 
ATOM 4763 N N   . LEU A 1 766  ? 176.186 149.264 157.187 1.00 23.42  ? 766  LEU A N   1 
ATOM 4764 C CA  . LEU A 1 766  ? 175.269 148.220 156.747 1.00 25.10  ? 766  LEU A CA  1 
ATOM 4765 C C   . LEU A 1 766  ? 174.544 147.558 157.910 1.00 25.98  ? 766  LEU A C   1 
ATOM 4766 O O   . LEU A 1 766  ? 173.597 146.797 157.679 1.00 29.99  ? 766  LEU A O   1 
ATOM 4767 C CB  . LEU A 1 766  ? 176.025 147.171 155.933 1.00 24.48  ? 766  LEU A CB  1 
ATOM 4768 C CG  . LEU A 1 766  ? 176.554 147.659 154.584 1.00 26.09  ? 766  LEU A CG  1 
ATOM 4769 C CD1 . LEU A 1 766  ? 177.388 146.585 153.912 1.00 26.01  ? 766  LEU A CD1 1 
ATOM 4770 C CD2 . LEU A 1 766  ? 175.408 148.094 153.688 1.00 24.47  ? 766  LEU A CD2 1 
ATOM 4771 N N   . VAL A 1 767  ? 174.967 147.827 159.147 1.00 24.26  ? 767  VAL A N   1 
ATOM 4772 C CA  . VAL A 1 767  ? 174.218 147.370 160.312 1.00 14.74  ? 767  VAL A CA  1 
ATOM 4773 C C   . VAL A 1 767  ? 172.823 147.976 160.310 1.00 18.82  ? 767  VAL A C   1 
ATOM 4774 O O   . VAL A 1 767  ? 171.876 147.379 160.833 1.00 24.55  ? 767  VAL A O   1 
ATOM 4775 C CB  . VAL A 1 767  ? 174.992 147.708 161.602 1.00 16.67  ? 767  VAL A CB  1 
ATOM 4776 C CG1 . VAL A 1 767  ? 174.241 147.220 162.831 1.00 24.54  ? 767  VAL A CG1 1 
ATOM 4777 C CG2 . VAL A 1 767  ? 176.385 147.106 161.553 1.00 21.68  ? 767  VAL A CG2 1 
ATOM 4778 N N   . ASP A 1 768  ? 172.668 149.160 159.713 1.00 20.65  ? 768  ASP A N   1 
ATOM 4779 C CA  . ASP A 1 768  ? 171.343 149.741 159.551 1.00 15.17  ? 768  ASP A CA  1 
ATOM 4780 C C   . ASP A 1 768  ? 170.474 148.841 158.693 1.00 14.33  ? 768  ASP A C   1 
ATOM 4781 O O   . ASP A 1 768  ? 169.365 148.514 159.075 1.00 20.64  ? 768  ASP A O   1 
ATOM 4782 C CB  . ASP A 1 768  ? 171.454 151.130 158.927 1.00 17.41  ? 768  ASP A CB  1 
ATOM 4783 C CG  . ASP A 1 768  ? 172.093 152.140 159.857 1.00 25.34  ? 768  ASP A CG  1 
ATOM 4784 O OD1 . ASP A 1 768  ? 171.960 151.993 161.090 1.00 29.82  ? 768  ASP A OD1 1 
ATOM 4785 O OD2 . ASP A 1 768  ? 172.735 153.084 159.353 1.00 23.11  ? 768  ASP A OD2 1 
ATOM 4786 N N   . LEU A 1 769  ? 170.993 148.363 157.570 1.00 9.87   ? 769  LEU A N   1 
ATOM 4787 C CA  . LEU A 1 769  ? 170.233 147.452 156.719 1.00 12.84  ? 769  LEU A CA  1 
ATOM 4788 C C   . LEU A 1 769  ? 169.978 146.127 157.433 1.00 13.65  ? 769  LEU A C   1 
ATOM 4789 O O   . LEU A 1 769  ? 168.904 145.532 157.291 1.00 14.95  ? 769  LEU A O   1 
ATOM 4790 C CB  . LEU A 1 769  ? 171.005 147.204 155.426 1.00 13.36  ? 769  LEU A CB  1 
ATOM 4791 C CG  . LEU A 1 769  ? 170.366 146.356 154.352 1.00 11.53  ? 769  LEU A CG  1 
ATOM 4792 C CD1 . LEU A 1 769  ? 169.135 147.110 153.894 1.00 14.46  ? 769  LEU A CD1 1 
ATOM 4793 C CD2 . LEU A 1 769  ? 171.270 146.086 153.193 1.00 20.39  ? 769  LEU A CD2 1 
ATOM 4794 N N   . TRP A 1 770  ? 170.955 145.649 158.211 1.00 8.99   ? 770  TRP A N   1 
ATOM 4795 C CA  . TRP A 1 770  ? 170.742 144.425 158.976 1.00 7.59   ? 770  TRP A CA  1 
ATOM 4796 C C   . TRP A 1 770  ? 169.596 144.590 159.964 1.00 9.64   ? 770  TRP A C   1 
ATOM 4797 O O   . TRP A 1 770  ? 168.773 143.685 160.120 1.00 8.20   ? 770  TRP A O   1 
ATOM 4798 C CB  . TRP A 1 770  ? 172.021 144.013 159.708 1.00 7.42   ? 770  TRP A CB  1 
ATOM 4799 C CG  . TRP A 1 770  ? 171.852 142.758 160.530 1.00 8.04   ? 770  TRP A CG  1 
ATOM 4800 C CD1 . TRP A 1 770  ? 172.223 141.496 160.175 1.00 12.40  ? 770  TRP A CD1 1 
ATOM 4801 C CD2 . TRP A 1 770  ? 171.285 142.651 161.846 1.00 13.11  ? 770  TRP A CD2 1 
ATOM 4802 N NE1 . TRP A 1 770  ? 171.912 140.609 161.175 1.00 14.78  ? 770  TRP A NE1 1 
ATOM 4803 C CE2 . TRP A 1 770  ? 171.337 141.293 162.212 1.00 13.78  ? 770  TRP A CE2 1 
ATOM 4804 C CE3 . TRP A 1 770  ? 170.737 143.570 162.746 1.00 13.94  ? 770  TRP A CE3 1 
ATOM 4805 C CZ2 . TRP A 1 770  ? 170.860 140.833 163.437 1.00 10.27  ? 770  TRP A CZ2 1 
ATOM 4806 C CZ3 . TRP A 1 770  ? 170.263 143.111 163.957 1.00 10.53  ? 770  TRP A CZ3 1 
ATOM 4807 C CH2 . TRP A 1 770  ? 170.329 141.756 164.293 1.00 12.50  ? 770  TRP A CH2 1 
ATOM 4808 N N   . SER A 1 771  ? 169.539 145.729 160.654 1.00 13.18  ? 771  SER A N   1 
ATOM 4809 C CA  . SER A 1 771  ? 168.451 145.977 161.594 1.00 5.81   ? 771  SER A CA  1 
ATOM 4810 C C   . SER A 1 771  ? 167.113 146.071 160.874 1.00 10.00  ? 771  SER A C   1 
ATOM 4811 O O   . SER A 1 771  ? 166.105 145.527 161.344 1.00 17.33  ? 771  SER A O   1 
ATOM 4812 C CB  . SER A 1 771  ? 168.725 147.253 162.387 1.00 7.39   ? 771  SER A CB  1 
ATOM 4813 O OG  . SER A 1 771  ? 167.566 147.678 163.081 1.00 17.76  ? 771  SER A OG  1 
ATOM 4814 N N   . LEU A 1 772  ? 167.090 146.744 159.724 1.00 8.50   ? 772  LEU A N   1 
ATOM 4815 C CA  . LEU A 1 772  ? 165.849 146.866 158.965 1.00 3.21   ? 772  LEU A CA  1 
ATOM 4816 C C   . LEU A 1 772  ? 165.329 145.503 158.530 1.00 1.25   ? 772  LEU A C   1 
ATOM 4817 O O   . LEU A 1 772  ? 164.127 145.232 158.621 1.00 5.44   ? 772  LEU A O   1 
ATOM 4818 C CB  . LEU A 1 772  ? 166.066 147.777 157.757 1.00 9.48   ? 772  LEU A CB  1 
ATOM 4819 C CG  . LEU A 1 772  ? 166.083 149.276 158.059 1.00 10.64  ? 772  LEU A CG  1 
ATOM 4820 C CD1 . LEU A 1 772  ? 167.268 149.717 158.777 1.00 16.78  ? 772  LEU A CD1 1 
ATOM 4821 C CD2 . LEU A 1 772  ? 165.971 150.062 156.772 1.00 12.91  ? 772  LEU A CD2 1 
ATOM 4822 N N   . PHE A 1 773  ? 166.217 144.623 158.066 1.00 4.46   ? 773  PHE A N   1 
ATOM 4823 C CA  . PHE A 1 773  ? 165.756 143.306 157.636 1.00 4.35   ? 773  PHE A CA  1 
ATOM 4824 C C   . PHE A 1 773  ? 165.512 142.354 158.799 1.00 5.06   ? 773  PHE A C   1 
ATOM 4825 O O   . PHE A 1 773  ? 164.687 141.447 158.675 1.00 6.00   ? 773  PHE A O   1 
ATOM 4826 C CB  . PHE A 1 773  ? 166.732 142.699 156.632 1.00 1.98   ? 773  PHE A CB  1 
ATOM 4827 C CG  . PHE A 1 773  ? 166.768 143.432 155.338 1.00 7.32   ? 773  PHE A CG  1 
ATOM 4828 C CD1 . PHE A 1 773  ? 165.791 143.214 154.380 1.00 6.28   ? 773  PHE A CD1 1 
ATOM 4829 C CD2 . PHE A 1 773  ? 167.724 144.334 155.059 1.00 10.98  ? 773  PHE A CD2 1 
ATOM 4830 C CE1 . PHE A 1 773  ? 165.801 143.896 153.179 1.00 10.62  ? 773  PHE A CE1 1 
ATOM 4831 C CE2 . PHE A 1 773  ? 167.674 144.918 153.864 1.00 8.10   ? 773  PHE A CE2 1 
ATOM 4832 C CZ  . PHE A 1 773  ? 166.779 144.790 152.939 1.00 15.08  ? 773  PHE A CZ  1 
ATOM 4833 N N   . ASP A 1 774  ? 166.198 142.530 159.928 1.00 8.58   ? 774  ASP A N   1 
ATOM 4834 C CA  . ASP A 1 774  ? 165.839 141.769 161.118 1.00 0.00   ? 774  ASP A CA  1 
ATOM 4835 C C   . ASP A 1 774  ? 164.457 142.162 161.613 1.00 0.97   ? 774  ASP A C   1 
ATOM 4836 O O   . ASP A 1 774  ? 163.748 141.339 162.200 1.00 9.64   ? 774  ASP A O   1 
ATOM 4837 C CB  . ASP A 1 774  ? 166.881 141.976 162.215 1.00 3.31   ? 774  ASP A CB  1 
ATOM 4838 C CG  . ASP A 1 774  ? 166.753 140.968 163.336 1.00 13.04  ? 774  ASP A CG  1 
ATOM 4839 O OD1 . ASP A 1 774  ? 166.404 141.373 164.464 1.00 17.23  ? 774  ASP A OD1 1 
ATOM 4840 O OD2 . ASP A 1 774  ? 167.001 139.770 163.089 1.00 15.32  ? 774  ASP A OD2 1 
ATOM 4841 N N   . PHE A 1 775  ? 164.071 143.419 161.397 1.00 4.86   ? 775  PHE A N   1 
ATOM 4842 C CA  . PHE A 1 775  ? 162.690 143.821 161.629 1.00 0.25   ? 775  PHE A CA  1 
ATOM 4843 C C   . PHE A 1 775  ? 161.756 143.175 160.611 1.00 1.41   ? 775  PHE A C   1 
ATOM 4844 O O   . PHE A 1 775  ? 160.722 142.603 160.975 1.00 1.71   ? 775  PHE A O   1 
ATOM 4845 C CB  . PHE A 1 775  ? 162.580 145.344 161.565 1.00 2.75   ? 775  PHE A CB  1 
ATOM 4846 C CG  . PHE A 1 775  ? 161.193 145.837 161.285 1.00 5.05   ? 775  PHE A CG  1 
ATOM 4847 C CD1 . PHE A 1 775  ? 160.201 145.725 162.241 1.00 0.00   ? 775  PHE A CD1 1 
ATOM 4848 C CD2 . PHE A 1 775  ? 160.873 146.385 160.054 1.00 3.44   ? 775  PHE A CD2 1 
ATOM 4849 C CE1 . PHE A 1 775  ? 158.929 146.176 161.985 1.00 0.00   ? 775  PHE A CE1 1 
ATOM 4850 C CE2 . PHE A 1 775  ? 159.597 146.828 159.793 1.00 0.55   ? 775  PHE A CE2 1 
ATOM 4851 C CZ  . PHE A 1 775  ? 158.625 146.706 160.752 1.00 0.54   ? 775  PHE A CZ  1 
ATOM 4852 N N   . ALA A 1 776  ? 162.118 143.244 159.328 1.00 2.92   ? 776  ALA A N   1 
ATOM 4853 C CA  . ALA A 1 776  ? 161.232 142.798 158.257 1.00 0.00   ? 776  ALA A CA  1 
ATOM 4854 C C   . ALA A 1 776  ? 161.256 141.281 158.093 1.00 5.13   ? 776  ALA A C   1 
ATOM 4855 O O   . ALA A 1 776  ? 160.224 140.616 158.222 1.00 12.03  ? 776  ALA A O   1 
ATOM 4856 C CB  . ALA A 1 776  ? 161.616 143.487 156.946 1.00 0.00   ? 776  ALA A CB  1 
ATOM 4857 N N   . GLN A 1 777  ? 162.425 140.717 157.803 1.00 9.16   ? 777  GLN A N   1 
ATOM 4858 C CA  . GLN A 1 777  ? 162.614 139.275 157.577 1.00 5.68   ? 777  GLN A CA  1 
ATOM 4859 C C   . GLN A 1 777  ? 163.693 138.763 158.478 1.00 8.06   ? 777  GLN A C   1 
ATOM 4860 O O   . GLN A 1 777  ? 164.881 138.682 158.095 1.00 9.99   ? 777  GLN A O   1 
ATOM 4861 C CB  . GLN A 1 777  ? 162.934 138.997 156.109 1.00 0.07   ? 777  GLN A CB  1 
ATOM 4862 C CG  . GLN A 1 777  ? 163.036 137.521 155.771 1.00 6.74   ? 777  GLN A CG  1 
ATOM 4863 C CD  . GLN A 1 777  ? 161.719 136.800 155.941 1.00 10.76  ? 777  GLN A CD  1 
ATOM 4864 O OE1 . GLN A 1 777  ? 160.673 137.288 155.514 1.00 10.67  ? 777  GLN A OE1 1 
ATOM 4865 N NE2 . GLN A 1 777  ? 161.760 135.634 156.571 1.00 11.73  ? 777  GLN A NE2 1 
ATOM 4866 N N   . PRO A 1 778  ? 163.382 138.419 159.715 1.00 2.95   ? 778  PRO A N   1 
ATOM 4867 C CA  . PRO A 1 778  ? 164.343 137.917 160.692 1.00 0.90   ? 778  PRO A CA  1 
ATOM 4868 C C   . PRO A 1 778  ? 164.996 136.645 160.180 1.00 6.74   ? 778  PRO A C   1 
ATOM 4869 O O   . PRO A 1 778  ? 164.323 135.746 159.664 1.00 11.91  ? 778  PRO A O   1 
ATOM 4870 C CB  . PRO A 1 778  ? 163.481 137.667 161.936 1.00 0.00   ? 778  PRO A CB  1 
ATOM 4871 C CG  . PRO A 1 778  ? 162.121 138.096 161.608 1.00 0.00   ? 778  PRO A CG  1 
ATOM 4872 C CD  . PRO A 1 778  ? 161.941 138.443 160.199 1.00 2.80   ? 778  PRO A CD  1 
ATOM 4873 N N   . GLY A 1 779  ? 166.300 136.608 160.323 1.00 6.87   ? 779  GLY A N   1 
ATOM 4874 C CA  . GLY A 1 779  ? 167.081 135.468 159.919 1.00 7.80   ? 779  GLY A CA  1 
ATOM 4875 C C   . GLY A 1 779  ? 167.529 135.464 158.474 1.00 10.80  ? 779  GLY A C   1 
ATOM 4876 O O   . GLY A 1 779  ? 168.295 134.573 158.086 1.00 16.42  ? 779  GLY A O   1 
ATOM 4877 N N   . LEU A 1 780  ? 167.075 136.421 157.660 1.00 9.76   ? 780  LEU A N   1 
ATOM 4878 C CA  . LEU A 1 780  ? 167.524 136.486 156.273 1.00 8.07   ? 780  LEU A CA  1 
ATOM 4879 C C   . LEU A 1 780  ? 169.018 136.770 156.193 1.00 12.87  ? 780  LEU A C   1 
ATOM 4880 O O   . LEU A 1 780  ? 169.756 136.082 155.479 1.00 18.29  ? 780  LEU A O   1 
ATOM 4881 C CB  . LEU A 1 780  ? 166.737 137.553 155.513 1.00 5.52   ? 780  LEU A CB  1 
ATOM 4882 C CG  . LEU A 1 780  ? 167.073 137.677 154.026 1.00 4.39   ? 780  LEU A CG  1 
ATOM 4883 C CD1 . LEU A 1 780  ? 166.740 136.390 153.291 1.00 10.58  ? 780  LEU A CD1 1 
ATOM 4884 C CD2 . LEU A 1 780  ? 166.350 138.857 153.403 1.00 7.44   ? 780  LEU A CD2 1 
ATOM 4885 N N   . LEU A 1 781  ? 169.483 137.778 156.926 1.00 2.67   ? 781  LEU A N   1 
ATOM 4886 C CA  . LEU A 1 781  ? 170.892 138.136 156.959 1.00 6.71   ? 781  LEU A CA  1 
ATOM 4887 C C   . LEU A 1 781  ? 171.646 137.426 158.074 1.00 15.10  ? 781  LEU A C   1 
ATOM 4888 O O   . LEU A 1 781  ? 172.834 137.696 158.273 1.00 20.37  ? 781  LEU A O   1 
ATOM 4889 C CB  . LEU A 1 781  ? 171.045 139.651 157.105 1.00 8.56   ? 781  LEU A CB  1 
ATOM 4890 C CG  . LEU A 1 781  ? 170.258 140.495 156.101 1.00 10.81  ? 781  LEU A CG  1 
ATOM 4891 C CD1 . LEU A 1 781  ? 170.564 141.970 156.277 1.00 6.12   ? 781  LEU A CD1 1 
ATOM 4892 C CD2 . LEU A 1 781  ? 170.555 140.051 154.678 1.00 15.01  ? 781  LEU A CD2 1 
ATOM 4893 N N   . GLY A 1 782  ? 170.985 136.530 158.798 1.00 12.88  ? 782  GLY A N   1 
ATOM 4894 C CA  . GLY A 1 782  ? 171.629 135.819 159.878 1.00 16.56  ? 782  GLY A CA  1 
ATOM 4895 C C   . GLY A 1 782  ? 171.829 136.697 161.099 1.00 19.03  ? 782  GLY A C   1 
ATOM 4896 O O   . GLY A 1 782  ? 171.213 137.755 161.258 1.00 23.08  ? 782  GLY A O   1 
ATOM 4897 N N   . ALA A 1 783  ? 172.711 136.235 161.979 1.00 21.58  ? 783  ALA A N   1 
ATOM 4898 C CA  . ALA A 1 783  ? 173.026 136.985 163.182 1.00 22.12  ? 783  ALA A CA  1 
ATOM 4899 C C   . ALA A 1 783  ? 173.846 138.226 162.833 1.00 21.95  ? 783  ALA A C   1 
ATOM 4900 O O   . ALA A 1 783  ? 174.434 138.337 161.754 1.00 25.74  ? 783  ALA A O   1 
ATOM 4901 C CB  . ALA A 1 783  ? 173.773 136.102 164.179 1.00 26.20  ? 783  ALA A CB  1 
ATOM 4902 N N   . LEU A 1 784  ? 173.872 139.176 163.769 1.00 20.71  ? 784  LEU A N   1 
ATOM 4903 C CA  . LEU A 1 784  ? 174.569 140.433 163.521 1.00 19.27  ? 784  LEU A CA  1 
ATOM 4904 C C   . LEU A 1 784  ? 176.078 140.243 163.445 1.00 23.95  ? 784  LEU A C   1 
ATOM 4905 O O   . LEU A 1 784  ? 176.744 140.925 162.658 1.00 31.51  ? 784  LEU A O   1 
ATOM 4906 C CB  . LEU A 1 784  ? 174.210 141.455 164.600 1.00 21.08  ? 784  LEU A CB  1 
ATOM 4907 C CG  . LEU A 1 784  ? 174.814 142.852 164.445 1.00 26.70  ? 784  LEU A CG  1 
ATOM 4908 C CD1 . LEU A 1 784  ? 174.329 143.518 163.171 1.00 25.99  ? 784  LEU A CD1 1 
ATOM 4909 C CD2 . LEU A 1 784  ? 174.482 143.711 165.651 1.00 29.73  ? 784  LEU A CD2 1 
ATOM 4910 N N   . ASN A 1 785  ? 176.637 139.330 164.243 1.00 31.38  ? 785  ASN A N   1 
ATOM 4911 C CA  . ASN A 1 785  ? 178.084 139.133 164.236 1.00 37.57  ? 785  ASN A CA  1 
ATOM 4912 C C   . ASN A 1 785  ? 178.561 138.560 162.907 1.00 39.24  ? 785  ASN A C   1 
ATOM 4913 O O   . ASN A 1 785  ? 179.550 139.035 162.334 1.00 40.98  ? 785  ASN A O   1 
ATOM 4914 C CB  . ASN A 1 785  ? 178.501 138.226 165.395 1.00 38.76  ? 785  ASN A CB  1 
ATOM 4915 C CG  . ASN A 1 785  ? 177.618 137.006 165.526 1.00 40.03  ? 785  ASN A CG  1 
ATOM 4916 O OD1 . ASN A 1 785  ? 176.396 137.117 165.588 1.00 42.03  ? 785  ASN A OD1 1 
ATOM 4917 N ND2 . ASN A 1 785  ? 178.233 135.830 165.565 1.00 41.27  ? 785  ASN A ND2 1 
ATOM 4918 N N   . GLU A 1 786  ? 177.876 137.531 162.401 1.00 34.66  ? 786  GLU A N   1 
ATOM 4919 C CA  . GLU A 1 786  ? 178.292 136.935 161.136 1.00 34.56  ? 786  GLU A CA  1 
ATOM 4920 C C   . GLU A 1 786  ? 178.037 137.881 159.968 1.00 36.44  ? 786  GLU A C   1 
ATOM 4921 O O   . GLU A 1 786  ? 178.833 137.937 159.024 1.00 42.51  ? 786  GLU A O   1 
ATOM 4922 C CB  . GLU A 1 786  ? 177.597 135.588 160.924 1.00 36.64  ? 786  GLU A CB  1 
ATOM 4923 C CG  . GLU A 1 786  ? 176.092 135.644 160.752 1.00 38.01  ? 786  GLU A CG  1 
ATOM 4924 C CD  . GLU A 1 786  ? 175.483 134.262 160.614 1.00 40.81  ? 786  GLU A CD  1 
ATOM 4925 O OE1 . GLU A 1 786  ? 176.241 133.272 160.677 1.00 42.58  ? 786  GLU A OE1 1 
ATOM 4926 O OE2 . GLU A 1 786  ? 174.251 134.163 160.444 1.00 38.58  ? 786  GLU A OE2 1 
ATOM 4927 N N   . PHE A 1 787  ? 176.941 138.643 160.020 1.00 28.99  ? 787  PHE A N   1 
ATOM 4928 C CA  . PHE A 1 787  ? 176.702 139.652 158.994 1.00 27.60  ? 787  PHE A CA  1 
ATOM 4929 C C   . PHE A 1 787  ? 177.807 140.700 158.999 1.00 29.94  ? 787  PHE A C   1 
ATOM 4930 O O   . PHE A 1 787  ? 178.280 141.120 157.937 1.00 37.69  ? 787  PHE A O   1 
ATOM 4931 C CB  . PHE A 1 787  ? 175.325 140.292 159.201 1.00 21.58  ? 787  PHE A CB  1 
ATOM 4932 C CG  . PHE A 1 787  ? 175.092 141.542 158.388 1.00 22.20  ? 787  PHE A CG  1 
ATOM 4933 C CD1 . PHE A 1 787  ? 175.550 142.777 158.824 1.00 24.08  ? 787  PHE A CD1 1 
ATOM 4934 C CD2 . PHE A 1 787  ? 174.414 141.477 157.183 1.00 22.29  ? 787  PHE A CD2 1 
ATOM 4935 C CE1 . PHE A 1 787  ? 175.338 143.915 158.075 1.00 26.31  ? 787  PHE A CE1 1 
ATOM 4936 C CE2 . PHE A 1 787  ? 174.198 142.615 156.432 1.00 22.48  ? 787  PHE A CE2 1 
ATOM 4937 C CZ  . PHE A 1 787  ? 174.661 143.835 156.878 1.00 24.10  ? 787  PHE A CZ  1 
ATOM 4938 N N   . GLY A 1 788  ? 178.226 141.140 160.187 1.00 31.85  ? 788  GLY A N   1 
ATOM 4939 C CA  . GLY A 1 788  ? 179.302 142.113 160.264 1.00 34.82  ? 788  GLY A CA  1 
ATOM 4940 C C   . GLY A 1 788  ? 180.622 141.574 159.747 1.00 42.84  ? 788  GLY A C   1 
ATOM 4941 O O   . GLY A 1 788  ? 181.302 142.233 158.956 1.00 46.50  ? 788  GLY A O   1 
ATOM 4942 N N   . LYS A 1 789  ? 180.997 140.364 160.170 1.00 43.25  ? 789  LYS A N   1 
ATOM 4943 C CA  . LYS A 1 789  ? 182.265 139.797 159.725 1.00 43.61  ? 789  LYS A CA  1 
ATOM 4944 C C   . LYS A 1 789  ? 182.220 139.347 158.271 1.00 44.33  ? 789  LYS A C   1 
ATOM 4945 O O   . LYS A 1 789  ? 183.270 139.043 157.698 1.00 45.58  ? 789  LYS A O   1 
ATOM 4946 C CB  . LYS A 1 789  ? 182.671 138.611 160.599 1.00 43.44  ? 789  LYS A CB  1 
ATOM 4947 C CG  . LYS A 1 789  ? 181.729 137.429 160.499 1.00 44.24  ? 789  LYS A CG  1 
ATOM 4948 C CD  . LYS A 1 789  ? 182.191 136.272 161.366 1.00 44.57  ? 789  LYS A CD  1 
ATOM 4949 C CE  . LYS A 1 789  ? 181.965 136.557 162.840 1.00 43.64  ? 789  LYS A CE  1 
ATOM 4950 N NZ  . LYS A 1 789  ? 182.294 135.374 163.679 1.00 43.41  ? 789  LYS A NZ  1 
ATOM 4951 N N   . GLN A 1 790  ? 181.033 139.278 157.671 1.00 41.01  ? 790  GLN A N   1 
ATOM 4952 C CA  . GLN A 1 790  ? 180.894 138.878 156.279 1.00 39.27  ? 790  GLN A CA  1 
ATOM 4953 C C   . GLN A 1 790  ? 180.564 140.032 155.346 1.00 42.24  ? 790  GLN A C   1 
ATOM 4954 O O   . GLN A 1 790  ? 180.896 139.964 154.161 1.00 45.50  ? 790  GLN A O   1 
ATOM 4955 C CB  . GLN A 1 790  ? 179.809 137.799 156.150 1.00 37.80  ? 790  GLN A CB  1 
ATOM 4956 C CG  . GLN A 1 790  ? 179.637 137.223 154.755 1.00 41.63  ? 790  GLN A CG  1 
ATOM 4957 C CD  . GLN A 1 790  ? 178.881 135.911 154.760 1.00 45.86  ? 790  GLN A CD  1 
ATOM 4958 O OE1 . GLN A 1 790  ? 178.873 135.190 155.757 1.00 45.45  ? 790  GLN A OE1 1 
ATOM 4959 N NE2 . GLN A 1 790  ? 178.240 135.593 153.641 1.00 43.81  ? 790  GLN A NE2 1 
ATOM 4960 N N   . TYR A 1 791  ? 179.943 141.098 155.852 1.00 41.79  ? 791  TYR A N   1 
ATOM 4961 C CA  . TYR A 1 791  ? 179.490 142.196 155.007 1.00 39.17  ? 791  TYR A CA  1 
ATOM 4962 C C   . TYR A 1 791  ? 179.909 143.582 155.477 1.00 39.74  ? 791  TYR A C   1 
ATOM 4963 O O   . TYR A 1 791  ? 179.819 144.523 154.681 1.00 39.70  ? 791  TYR A O   1 
ATOM 4964 C CB  . TYR A 1 791  ? 177.959 142.174 154.878 1.00 33.25  ? 791  TYR A CB  1 
ATOM 4965 C CG  . TYR A 1 791  ? 177.435 141.039 154.033 1.00 35.92  ? 791  TYR A CG  1 
ATOM 4966 C CD1 . TYR A 1 791  ? 177.934 140.811 152.758 1.00 37.57  ? 791  TYR A CD1 1 
ATOM 4967 C CD2 . TYR A 1 791  ? 176.445 140.193 154.510 1.00 40.60  ? 791  TYR A CD2 1 
ATOM 4968 C CE1 . TYR A 1 791  ? 177.459 139.772 151.981 1.00 39.40  ? 791  TYR A CE1 1 
ATOM 4969 C CE2 . TYR A 1 791  ? 175.962 139.151 153.740 1.00 39.79  ? 791  TYR A CE2 1 
ATOM 4970 C CZ  . TYR A 1 791  ? 176.473 138.945 152.477 1.00 40.57  ? 791  TYR A CZ  1 
ATOM 4971 O OH  . TYR A 1 791  ? 175.996 137.909 151.706 1.00 42.17  ? 791  TYR A OH  1 
ATOM 4972 N N   . VAL A 1 792  ? 180.355 143.750 156.719 1.00 45.07  ? 792  VAL A N   1 
ATOM 4973 C CA  . VAL A 1 792  ? 180.664 145.067 157.274 1.00 47.48  ? 792  VAL A CA  1 
ATOM 4974 C C   . VAL A 1 792  ? 182.171 145.284 157.388 1.00 49.56  ? 792  VAL A C   1 
ATOM 4975 O O   . VAL A 1 792  ? 182.714 146.228 156.815 1.00 49.07  ? 792  VAL A O   1 
ATOM 4976 C CB  . VAL A 1 792  ? 179.962 145.277 158.635 1.00 47.49  ? 792  VAL A CB  1 
ATOM 4977 C CG1 . VAL A 1 792  ? 180.640 146.383 159.425 1.00 47.40  ? 792  VAL A CG1 1 
ATOM 4978 C CG2 . VAL A 1 792  ? 178.497 145.594 158.429 1.00 43.83  ? 792  VAL A CG2 1 
ATOM 4979 N N   . ARG A 1 793  ? 182.865 144.412 158.124 1.00 54.59  ? 793  ARG A N   1 
ATOM 4980 C CA  . ARG A 1 793  ? 184.298 144.602 158.362 1.00 56.65  ? 793  ARG A CA  1 
ATOM 4981 C C   . ARG A 1 793  ? 185.096 144.630 157.082 1.00 57.15  ? 793  ARG A C   1 
ATOM 4982 O O   . ARG A 1 793  ? 185.999 145.497 156.951 1.00 56.68  ? 793  ARG A O   1 
ATOM 4983 C CB  . ARG A 1 793  ? 184.816 143.525 159.323 1.00 56.17  ? 793  ARG A CB  1 
ATOM 4984 C CG  . ARG A 1 793  ? 184.519 143.769 160.806 1.00 56.87  ? 793  ARG A CG  1 
ATOM 4985 C CD  . ARG A 1 793  ? 183.074 143.504 161.168 1.00 56.76  ? 793  ARG A CD  1 
ATOM 4986 N NE  . ARG A 1 793  ? 182.823 143.689 162.591 1.00 58.21  ? 793  ARG A NE  1 
ATOM 4987 C CZ  . ARG A 1 793  ? 182.973 142.743 163.507 1.00 58.59  ? 793  ARG A CZ  1 
ATOM 4988 N NH1 . ARG A 1 793  ? 183.398 141.532 163.187 1.00 57.61  ? 793  ARG A NH1 1 
ATOM 4989 N NH2 . ARG A 1 793  ? 182.684 143.017 164.776 1.00 55.09  ? 793  ARG A NH2 1 
ATOM 4990 N N   . PRO A 1 794  ? 184.846 143.777 156.068 1.00 57.87  ? 794  PRO A N   1 
ATOM 4991 C CA  . PRO A 1 794  ? 185.727 143.710 154.949 1.00 59.26  ? 794  PRO A CA  1 
ATOM 4992 C C   . PRO A 1 794  ? 185.313 144.571 153.764 1.00 59.39  ? 794  PRO A C   1 
ATOM 4993 O O   . PRO A 1 794  ? 185.852 144.419 152.660 1.00 58.31  ? 794  PRO A O   1 
ATOM 4994 C CB  . PRO A 1 794  ? 185.556 142.089 154.630 1.00 58.01  ? 794  PRO A CB  1 
ATOM 4995 C CG  . PRO A 1 794  ? 183.689 141.818 155.519 1.00 56.67  ? 794  PRO A CG  1 
ATOM 4996 C CD  . PRO A 1 794  ? 184.769 142.411 155.715 1.00 57.59  ? 794  PRO A CD  1 
ATOM 4997 N N   . ILE A 1 795  ? 184.334 145.460 153.952 1.00 57.74  ? 795  ILE A N   1 
ATOM 4998 C CA  . ILE A 1 795  ? 184.019 146.489 152.966 1.00 59.42  ? 795  ILE A CA  1 
ATOM 4999 C C   . ILE A 1 795  ? 184.071 147.838 153.672 1.00 57.47  ? 795  ILE A C   1 
ATOM 5000 O O   . ILE A 1 795  ? 184.358 148.871 153.056 1.00 58.43  ? 795  ILE A O   1 
ATOM 5001 C CB  . ILE A 1 795  ? 182.648 146.249 152.297 1.00 57.67  ? 795  ILE A CB  1 
ATOM 5002 C CG1 . ILE A 1 795  ? 182.630 144.930 151.519 1.00 56.45  ? 795  ILE A CG1 1 
ATOM 5003 C CG2 . ILE A 1 795  ? 182.285 147.377 151.334 1.00 56.44  ? 795  ILE A CG2 1 
ATOM 5004 C CD1 . ILE A 1 795  ? 182.212 143.722 152.327 1.00 54.05  ? 795  ILE A CD1 1 
ATOM 5005 N N   . GLU A 1 796  ? 183.822 147.831 154.978 1.00 51.42  ? 796  GLU A N   1 
ATOM 5006 C CA  . GLU A 1 796  ? 183.777 149.061 155.759 1.00 53.68  ? 796  GLU A CA  1 
ATOM 5007 C C   . GLU A 1 796  ? 184.769 149.002 156.918 1.00 55.73  ? 796  GLU A C   1 
ATOM 5008 O O   . GLU A 1 796  ? 184.793 148.037 157.684 1.00 54.15  ? 796  GLU A O   1 
ATOM 5009 C CB  . GLU A 1 796  ? 182.361 149.309 156.285 1.00 53.31  ? 796  GLU A CB  1 
ATOM 5010 C CG  . GLU A 1 796  ? 181.263 148.923 155.306 1.00 52.59  ? 796  GLU A CG  1 
ATOM 5011 C CD  . GLU A 1 796  ? 179.926 149.532 155.666 1.00 52.17  ? 796  GLU A CD  1 
ATOM 5012 O OE1 . GLU A 1 796  ? 179.111 149.762 154.749 1.00 49.10  ? 796  GLU A OE1 1 
ATOM 5013 O OE2 . GLU A 1 796  ? 179.693 149.780 156.866 1.00 50.67  ? 796  GLU A OE2 1 
ATOM 5014 N N   . THR A 1 803  ? 181.648 145.282 143.709 1.00 54.53  ? 803  THR A N   1 
ATOM 5015 C CA  . THR A 1 803  ? 182.223 144.430 144.743 1.00 58.33  ? 803  THR A CA  1 
ATOM 5016 C C   . THR A 1 803  ? 181.443 143.123 144.844 1.00 58.17  ? 803  THR A C   1 
ATOM 5017 O O   . THR A 1 803  ? 180.213 143.119 144.784 1.00 56.76  ? 803  THR A O   1 
ATOM 5018 C CB  . THR A 1 803  ? 182.238 145.136 146.111 1.00 59.52  ? 803  THR A CB  1 
ATOM 5019 O OG1 . THR A 1 803  ? 182.830 146.434 145.972 1.00 58.87  ? 803  THR A OG1 1 
ATOM 5020 C CG2 . THR A 1 803  ? 183.041 144.332 147.121 1.00 55.10  ? 803  THR A CG2 1 
ATOM 5021 N N   . GLU A 1 804  ? 182.170 142.011 144.987 1.00 57.71  ? 804  GLU A N   1 
ATOM 5022 C CA  . GLU A 1 804  ? 181.527 140.700 144.995 1.00 56.32  ? 804  GLU A CA  1 
ATOM 5023 C C   . GLU A 1 804  ? 180.647 140.509 146.228 1.00 57.56  ? 804  GLU A C   1 
ATOM 5024 O O   . GLU A 1 804  ? 179.530 139.988 146.122 1.00 56.30  ? 804  GLU A O   1 
ATOM 5025 C CB  . GLU A 1 804  ? 182.589 139.601 144.887 1.00 55.94  ? 804  GLU A CB  1 
ATOM 5026 C CG  . GLU A 1 804  ? 183.493 139.435 146.102 1.00 56.58  ? 804  GLU A CG  1 
ATOM 5027 C CD  . GLU A 1 804  ? 184.676 140.387 146.091 1.00 58.30  ? 804  GLU A CD  1 
ATOM 5028 O OE1 . GLU A 1 804  ? 184.650 141.369 145.318 1.00 57.80  ? 804  GLU A OE1 1 
ATOM 5029 O OE2 . GLU A 1 804  ? 185.635 140.154 146.856 1.00 57.67  ? 804  GLU A OE2 1 
ATOM 5030 N N   . ARG A 1 805  ? 181.123 140.927 147.405 1.00 55.10  ? 805  ARG A N   1 
ATOM 5031 C CA  . ARG A 1 805  ? 180.313 140.795 148.614 1.00 52.58  ? 805  ARG A CA  1 
ATOM 5032 C C   . ARG A 1 805  ? 179.100 141.714 148.565 1.00 51.29  ? 805  ARG A C   1 
ATOM 5033 O O   . ARG A 1 805  ? 178.000 141.329 148.981 1.00 51.21  ? 805  ARG A O   1 
ATOM 5034 C CB  . ARG A 1 805  ? 181.159 141.087 149.851 1.00 52.84  ? 805  ARG A CB  1 
ATOM 5035 C CG  . ARG A 1 805  ? 182.317 140.128 150.038 1.00 54.46  ? 805  ARG A CG  1 
ATOM 5036 C CD  . ARG A 1 805  ? 181.812 138.739 150.385 1.00 53.35  ? 805  ARG A CD  1 
ATOM 5037 N NE  . ARG A 1 805  ? 182.903 137.806 150.640 1.00 57.94  ? 805  ARG A NE  1 
ATOM 5038 C CZ  . ARG A 1 805  ? 182.740 136.515 150.895 1.00 56.52  ? 805  ARG A CZ  1 
ATOM 5039 N NH1 . ARG A 1 805  ? 181.537 135.966 150.937 1.00 54.93  ? 805  ARG A NH1 1 
ATOM 5040 N NH2 . ARG A 1 805  ? 183.810 135.757 151.112 1.00 54.56  ? 805  ARG A NH2 1 
ATOM 5041 N N   . LEU A 1 806  ? 179.288 142.933 148.063 1.00 44.82  ? 806  LEU A N   1 
ATOM 5042 C CA  . LEU A 1 806  ? 178.174 143.859 147.907 1.00 46.58  ? 806  LEU A CA  1 
ATOM 5043 C C   . LEU A 1 806  ? 177.121 143.296 146.957 1.00 47.49  ? 806  LEU A C   1 
ATOM 5044 O O   . LEU A 1 806  ? 175.919 143.364 147.240 1.00 48.13  ? 806  LEU A O   1 
ATOM 5045 C CB  . LEU A 1 806  ? 178.711 145.207 147.422 1.00 48.40  ? 806  LEU A CB  1 
ATOM 5046 C CG  . LEU A 1 806  ? 177.853 146.468 147.396 1.00 46.01  ? 806  LEU A CG  1 
ATOM 5047 C CD1 . LEU A 1 806  ? 178.744 147.692 147.335 1.00 46.77  ? 806  LEU A CD1 1 
ATOM 5048 C CD2 . LEU A 1 806  ? 176.991 146.426 146.176 1.00 44.52  ? 806  LEU A CD2 1 
ATOM 5049 N N   . GLU A 1 807  ? 177.553 142.727 145.829 1.00 44.85  ? 807  GLU A N   1 
ATOM 5050 C CA  . GLU A 1 807  ? 176.597 142.150 144.888 1.00 42.91  ? 807  GLU A CA  1 
ATOM 5051 C C   . GLU A 1 807  ? 175.911 140.922 145.476 1.00 43.93  ? 807  GLU A C   1 
ATOM 5052 O O   . GLU A 1 807  ? 174.726 140.684 145.216 1.00 43.13  ? 807  GLU A O   1 
ATOM 5053 C CB  . GLU A 1 807  ? 177.295 141.804 143.573 1.00 41.96  ? 807  GLU A CB  1 
ATOM 5054 C CG  . GLU A 1 807  ? 177.509 142.996 142.650 1.00 43.32  ? 807  GLU A CG  1 
ATOM 5055 C CD  . GLU A 1 807  ? 176.350 143.976 142.677 1.00 46.62  ? 807  GLU A CD  1 
ATOM 5056 O OE1 . GLU A 1 807  ? 176.556 145.130 143.109 1.00 46.67  ? 807  GLU A OE1 1 
ATOM 5057 O OE2 . GLU A 1 807  ? 175.235 143.595 142.264 1.00 47.17  ? 807  GLU A OE2 1 
ATOM 5058 N N   . SER A 1 808  ? 176.637 140.129 146.267 1.00 40.99  ? 808  SER A N   1 
ATOM 5059 C CA  . SER A 1 808  ? 176.023 138.976 146.920 1.00 37.89  ? 808  SER A CA  1 
ATOM 5060 C C   . SER A 1 808  ? 174.946 139.415 147.904 1.00 39.14  ? 808  SER A C   1 
ATOM 5061 O O   . SER A 1 808  ? 173.861 138.825 147.960 1.00 41.66  ? 808  SER A O   1 
ATOM 5062 C CB  . SER A 1 808  ? 177.092 138.142 147.624 1.00 39.15  ? 808  SER A CB  1 
ATOM 5063 O OG  . SER A 1 808  ? 177.673 138.860 148.697 1.00 40.67  ? 808  SER A OG  1 
ATOM 5064 N N   . LEU A 1 809  ? 175.228 140.457 148.690 1.00 33.04  ? 809  LEU A N   1 
ATOM 5065 C CA  . LEU A 1 809  ? 174.228 140.975 149.620 1.00 30.34  ? 809  LEU A CA  1 
ATOM 5066 C C   . LEU A 1 809  ? 173.030 141.551 148.872 1.00 28.90  ? 809  LEU A C   1 
ATOM 5067 O O   . LEU A 1 809  ? 171.878 141.380 149.296 1.00 31.31  ? 809  LEU A O   1 
ATOM 5068 C CB  . LEU A 1 809  ? 174.861 142.026 150.533 1.00 34.39  ? 809  LEU A CB  1 
ATOM 5069 C CG  . LEU A 1 809  ? 173.952 142.895 151.405 1.00 28.37  ? 809  LEU A CG  1 
ATOM 5070 C CD1 . LEU A 1 809  ? 173.065 142.038 152.294 1.00 28.64  ? 809  LEU A CD1 1 
ATOM 5071 C CD2 . LEU A 1 809  ? 174.780 143.857 152.242 1.00 28.17  ? 809  LEU A CD2 1 
ATOM 5072 N N   . ARG A 1 810  ? 173.284 142.236 147.753 1.00 29.54  ? 810  ARG A N   1 
ATOM 5073 C CA  . ARG A 1 810  ? 172.193 142.742 146.928 1.00 28.33  ? 810  ARG A CA  1 
ATOM 5074 C C   . ARG A 1 810  ? 171.314 141.612 146.412 1.00 26.98  ? 810  ARG A C   1 
ATOM 5075 O O   . ARG A 1 810  ? 170.085 141.717 146.435 1.00 27.86  ? 810  ARG A O   1 
ATOM 5076 C CB  . ARG A 1 810  ? 172.744 143.549 145.755 1.00 28.16  ? 810  ARG A CB  1 
ATOM 5077 C CG  . ARG A 1 810  ? 171.683 144.354 145.031 1.00 33.28  ? 810  ARG A CG  1 
ATOM 5078 C CD  . ARG A 1 810  ? 172.307 145.330 144.061 1.00 31.54  ? 810  ARG A CD  1 
ATOM 5079 N NE  . ARG A 1 810  ? 173.452 146.000 144.661 1.00 33.48  ? 810  ARG A NE  1 
ATOM 5080 C CZ  . ARG A 1 810  ? 173.458 147.279 145.010 1.00 33.53  ? 810  ARG A CZ  1 
ATOM 5081 N NH1 . ARG A 1 810  ? 172.409 148.053 144.814 1.00 28.62  ? 810  ARG A NH1 1 
ATOM 5082 N NH2 . ARG A 1 810  ? 174.538 147.794 145.577 1.00 32.06  ? 810  ARG A NH2 1 
ATOM 5083 N N   . ALA A 1 811  ? 171.923 140.532 145.922 1.00 24.74  ? 811  ALA A N   1 
ATOM 5084 C CA  . ALA A 1 811  ? 171.135 139.399 145.453 1.00 20.04  ? 811  ALA A CA  1 
ATOM 5085 C C   . ALA A 1 811  ? 170.385 138.734 146.597 1.00 23.37  ? 811  ALA A C   1 
ATOM 5086 O O   . ALA A 1 811  ? 169.274 138.229 146.400 1.00 26.29  ? 811  ALA A O   1 
ATOM 5087 C CB  . ALA A 1 811  ? 172.033 138.387 144.743 1.00 25.40  ? 811  ALA A CB  1 
ATOM 5088 N N   . LEU A 1 812  ? 170.977 138.721 147.792 1.00 22.90  ? 812  LEU A N   1 
ATOM 5089 C CA  . LEU A 1 812  ? 170.308 138.147 148.953 1.00 20.02  ? 812  LEU A CA  1 
ATOM 5090 C C   . LEU A 1 812  ? 169.059 138.936 149.325 1.00 19.15  ? 812  LEU A C   1 
ATOM 5091 O O   . LEU A 1 812  ? 168.025 138.348 149.661 1.00 20.41  ? 812  LEU A O   1 
ATOM 5092 C CB  . LEU A 1 812  ? 171.278 138.089 150.133 1.00 21.59  ? 812  LEU A CB  1 
ATOM 5093 C CG  . LEU A 1 812  ? 170.832 137.297 151.361 1.00 24.44  ? 812  LEU A CG  1 
ATOM 5094 C CD1 . LEU A 1 812  ? 170.437 135.884 150.971 1.00 22.15  ? 812  LEU A CD1 1 
ATOM 5095 C CD2 . LEU A 1 812  ? 171.933 137.279 152.405 1.00 22.50  ? 812  LEU A CD2 1 
ATOM 5096 N N   . ILE A 1 813  ? 169.133 140.270 149.276 1.00 16.02  ? 813  ILE A N   1 
ATOM 5097 C CA  . ILE A 1 813  ? 168.000 141.087 149.713 1.00 10.00  ? 813  ILE A CA  1 
ATOM 5098 C C   . ILE A 1 813  ? 167.080 141.518 148.577 1.00 18.73  ? 813  ILE A C   1 
ATOM 5099 O O   . ILE A 1 813  ? 166.048 142.152 148.844 1.00 21.19  ? 813  ILE A O   1 
ATOM 5100 C CB  . ILE A 1 813  ? 168.460 142.352 150.465 1.00 9.18   ? 813  ILE A CB  1 
ATOM 5101 C CG1 . ILE A 1 813  ? 169.294 143.250 149.553 1.00 11.78  ? 813  ILE A CG1 1 
ATOM 5102 C CG2 . ILE A 1 813  ? 169.239 141.976 151.713 1.00 14.63  ? 813  ILE A CG2 1 
ATOM 5103 C CD1 . ILE A 1 813  ? 169.584 144.609 150.144 1.00 13.49  ? 813  ILE A CD1 1 
ATOM 5104 N N   . GLU A 1 814  ? 167.414 141.201 147.325 1.00 19.09  ? 814  GLU A N   1 
ATOM 5105 C CA  . GLU A 1 814  ? 166.598 141.657 146.200 1.00 8.32   ? 814  GLU A CA  1 
ATOM 5106 C C   . GLU A 1 814  ? 165.163 141.144 146.230 1.00 12.64  ? 814  GLU A C   1 
ATOM 5107 O O   . GLU A 1 814  ? 164.246 141.949 145.988 1.00 13.45  ? 814  GLU A O   1 
ATOM 5108 C CB  . GLU A 1 814  ? 167.290 141.289 144.882 1.00 12.97  ? 814  GLU A CB  1 
ATOM 5109 C CG  . GLU A 1 814  ? 166.660 141.923 143.652 1.00 15.68  ? 814  GLU A CG  1 
ATOM 5110 C CD  . GLU A 1 814  ? 165.645 141.017 142.980 1.00 21.56  ? 814  GLU A CD  1 
ATOM 5111 O OE1 . GLU A 1 814  ? 164.738 141.539 142.298 1.00 19.53  ? 814  GLU A OE1 1 
ATOM 5112 O OE2 . GLU A 1 814  ? 165.753 139.782 143.134 1.00 22.65  ? 814  GLU A OE2 1 
ATOM 5113 N N   . PRO A 1 815  ? 164.885 139.857 146.480 1.00 16.26  ? 815  PRO A N   1 
ATOM 5114 C CA  . PRO A 1 815  ? 163.478 139.418 146.476 1.00 10.10  ? 815  PRO A CA  1 
ATOM 5115 C C   . PRO A 1 815  ? 162.600 140.183 147.446 1.00 12.16  ? 815  PRO A C   1 
ATOM 5116 O O   . PRO A 1 815  ? 161.410 140.381 147.170 1.00 18.35  ? 815  PRO A O   1 
ATOM 5117 C CB  . PRO A 1 815  ? 163.561 137.936 146.864 1.00 7.95   ? 815  PRO A CB  1 
ATOM 5118 C CG  . PRO A 1 815  ? 164.932 137.515 146.569 1.00 9.08   ? 815  PRO A CG  1 
ATOM 5119 C CD  . PRO A 1 815  ? 165.818 138.715 146.499 1.00 11.48  ? 815  PRO A CD  1 
ATOM 5120 N N   . GLN A 1 816  ? 163.149 140.619 148.575 1.00 10.54  ? 816  GLN A N   1 
ATOM 5121 C CA  . GLN A 1 816  ? 162.369 141.264 149.618 1.00 6.57   ? 816  GLN A CA  1 
ATOM 5122 C C   . GLN A 1 816  ? 162.400 142.784 149.537 1.00 7.77   ? 816  GLN A C   1 
ATOM 5123 O O   . GLN A 1 816  ? 161.679 143.441 150.294 1.00 17.28  ? 816  GLN A O   1 
ATOM 5124 C CB  . GLN A 1 816  ? 162.883 140.818 150.991 1.00 8.41   ? 816  GLN A CB  1 
ATOM 5125 C CG  . GLN A 1 816  ? 162.733 139.329 151.247 1.00 6.80   ? 816  GLN A CG  1 
ATOM 5126 C CD  . GLN A 1 816  ? 161.420 138.968 151.895 1.00 12.66  ? 816  GLN A CD  1 
ATOM 5127 O OE1 . GLN A 1 816  ? 161.305 138.931 153.118 1.00 14.18  ? 816  GLN A OE1 1 
ATOM 5128 N NE2 . GLN A 1 816  ? 160.412 138.709 151.075 1.00 12.87  ? 816  GLN A NE2 1 
ATOM 5129 N N   . THR A 1 817  ? 163.202 143.353 148.641 1.00 7.93   ? 817  THR A N   1 
ATOM 5130 C CA  . THR A 1 817  ? 163.404 144.792 148.550 1.00 9.97   ? 817  THR A CA  1 
ATOM 5131 C C   . THR A 1 817  ? 162.855 145.316 147.232 1.00 13.09  ? 817  THR A C   1 
ATOM 5132 O O   . THR A 1 817  ? 163.104 144.730 146.173 1.00 15.94  ? 817  THR A O   1 
ATOM 5133 C CB  . THR A 1 817  ? 164.889 145.147 148.662 1.00 8.57   ? 817  THR A CB  1 
ATOM 5134 O OG1 . THR A 1 817  ? 165.474 144.435 149.759 1.00 8.59   ? 817  THR A OG1 1 
ATOM 5135 C CG2 . THR A 1 817  ? 165.072 146.640 148.870 1.00 6.59   ? 817  THR A CG2 1 
ATOM 5136 N N   . LEU A 1 818  ? 162.114 146.418 147.299 1.00 7.35   ? 818  LEU A N   1 
ATOM 5137 C CA  . LEU A 1 818  ? 161.670 147.147 146.119 1.00 9.37   ? 818  LEU A CA  1 
ATOM 5138 C C   . LEU A 1 818  ? 162.200 148.569 146.203 1.00 17.37  ? 818  LEU A C   1 
ATOM 5139 O O   . LEU A 1 818  ? 161.795 149.334 147.085 1.00 21.09  ? 818  LEU A O   1 
ATOM 5140 C CB  . LEU A 1 818  ? 160.146 147.155 146.000 1.00 7.29   ? 818  LEU A CB  1 
ATOM 5141 C CG  . LEU A 1 818  ? 159.638 147.383 144.575 1.00 12.93  ? 818  LEU A CG  1 
ATOM 5142 C CD1 . LEU A 1 818  ? 160.310 146.421 143.609 1.00 15.92  ? 818  LEU A CD1 1 
ATOM 5143 C CD2 . LEU A 1 818  ? 158.131 147.259 144.502 1.00 11.46  ? 818  LEU A CD2 1 
ATOM 5144 N N   . ARG A 1 819  ? 163.104 148.919 145.294 1.00 21.34  ? 819  ARG A N   1 
ATOM 5145 C CA  . ARG A 1 819  ? 163.639 150.271 145.212 1.00 19.39  ? 819  ARG A CA  1 
ATOM 5146 C C   . ARG A 1 819  ? 163.471 150.779 143.792 1.00 29.37  ? 819  ARG A C   1 
ATOM 5147 O O   . ARG A 1 819  ? 163.884 150.113 142.836 1.00 30.66  ? 819  ARG A O   1 
ATOM 5148 C CB  . ARG A 1 819  ? 165.111 150.323 145.627 1.00 18.11  ? 819  ARG A CB  1 
ATOM 5149 C CG  . ARG A 1 819  ? 165.683 151.731 145.627 1.00 20.83  ? 819  ARG A CG  1 
ATOM 5150 C CD  . ARG A 1 819  ? 167.121 151.736 146.097 1.00 25.90  ? 819  ARG A CD  1 
ATOM 5151 N NE  . ARG A 1 819  ? 167.692 153.077 146.149 1.00 28.15  ? 819  ARG A NE  1 
ATOM 5152 C CZ  . ARG A 1 819  ? 168.319 153.665 145.140 1.00 30.58  ? 819  ARG A CZ  1 
ATOM 5153 N NH1 . ARG A 1 819  ? 168.501 153.046 143.986 1.00 29.14  ? 819  ARG A NH1 1 
ATOM 5154 N NH2 . ARG A 1 819  ? 168.773 154.905 145.293 1.00 29.77  ? 819  ARG A NH2 1 
ATOM 5155 N N   . ARG A 1 820  ? 162.858 151.948 143.659 1.00 30.24  ? 820  ARG A N   1 
ATOM 5156 C CA  . ARG A 1 820  ? 162.743 152.647 142.391 1.00 25.97  ? 820  ARG A CA  1 
ATOM 5157 C C   . ARG A 1 820  ? 163.106 154.103 142.618 1.00 29.08  ? 820  ARG A C   1 
ATOM 5158 O O   . ARG A 1 820  ? 162.617 154.733 143.560 1.00 26.24  ? 820  ARG A O   1 
ATOM 5159 C CB  . ARG A 1 820  ? 161.331 152.525 141.811 1.00 25.70  ? 820  ARG A CB  1 
ATOM 5160 C CG  . ARG A 1 820  ? 160.963 151.110 141.401 1.00 24.15  ? 820  ARG A CG  1 
ATOM 5161 C CD  . ARG A 1 820  ? 159.467 150.892 141.463 1.00 24.47  ? 820  ARG A CD  1 
ATOM 5162 N NE  . ARG A 1 820  ? 158.936 151.226 142.778 1.00 23.27  ? 820  ARG A NE  1 
ATOM 5163 C CZ  . ARG A 1 820  ? 157.675 151.045 143.142 1.00 26.43  ? 820  ARG A CZ  1 
ATOM 5164 N NH1 . ARG A 1 820  ? 156.787 150.520 142.316 1.00 27.68  ? 820  ARG A NH1 1 
ATOM 5165 N NH2 . ARG A 1 820  ? 157.297 151.398 144.367 1.00 25.58  ? 820  ARG A NH2 1 
ATOM 5166 N N   . THR A 1 821  ? 163.981 154.629 141.771 1.00 39.63  ? 821  THR A N   1 
ATOM 5167 C CA  . THR A 1 821  ? 164.432 156.005 141.890 1.00 39.14  ? 821  THR A CA  1 
ATOM 5168 C C   . THR A 1 821  ? 163.638 156.902 140.949 1.00 41.49  ? 821  THR A C   1 
ATOM 5169 O O   . THR A 1 821  ? 162.846 156.442 140.124 1.00 41.91  ? 821  THR A O   1 
ATOM 5170 C CB  . THR A 1 821  ? 165.932 156.113 141.603 1.00 37.63  ? 821  THR A CB  1 
ATOM 5171 O OG1 . THR A 1 821  ? 166.257 155.339 140.444 1.00 40.73  ? 821  THR A OG1 1 
ATOM 5172 C CG2 . THR A 1 821  ? 166.731 155.589 142.777 1.00 37.84  ? 821  THR A CG2 1 
ATOM 5173 N N   . LYS A 1 822  ? 163.858 158.210 141.093 1.00 46.40  ? 822  LYS A N   1 
ATOM 5174 C CA  . LYS A 1 822  ? 163.112 159.173 140.291 1.00 44.36  ? 822  LYS A CA  1 
ATOM 5175 C C   . LYS A 1 822  ? 163.512 159.101 138.823 1.00 45.88  ? 822  LYS A C   1 
ATOM 5176 O O   . LYS A 1 822  ? 162.670 159.278 137.935 1.00 43.37  ? 822  LYS A O   1 
ATOM 5177 C CB  . LYS A 1 822  ? 163.317 160.580 140.849 1.00 40.45  ? 822  LYS A CB  1 
ATOM 5178 C CG  . LYS A 1 822  ? 163.063 160.677 142.346 1.00 40.83  ? 822  LYS A CG  1 
ATOM 5179 C CD  . LYS A 1 822  ? 163.218 162.097 142.857 1.00 44.41  ? 822  LYS A CD  1 
ATOM 5180 C CE  . LYS A 1 822  ? 162.176 163.018 142.248 1.00 47.18  ? 822  LYS A CE  1 
ATOM 5181 N NZ  . LYS A 1 822  ? 160.963 163.128 143.103 1.00 43.73  ? 822  LYS A NZ  1 
ATOM 5182 N N   . GLU A 1 823  ? 164.791 158.835 138.543 1.00 46.86  ? 823  GLU A N   1 
ATOM 5183 C CA  . GLU A 1 823  ? 165.233 158.729 137.157 1.00 48.39  ? 823  GLU A CA  1 
ATOM 5184 C C   . GLU A 1 823  ? 164.720 157.466 136.476 1.00 50.51  ? 823  GLU A C   1 
ATOM 5185 O O   . GLU A 1 823  ? 164.685 157.417 135.242 1.00 52.65  ? 823  GLU A O   1 
ATOM 5186 C CB  . GLU A 1 823  ? 166.762 158.793 137.072 1.00 48.21  ? 823  GLU A CB  1 
ATOM 5187 C CG  . GLU A 1 823  ? 167.503 157.725 137.860 1.00 51.25  ? 823  GLU A CG  1 
ATOM 5188 C CD  . GLU A 1 823  ? 167.848 158.172 139.269 1.00 53.07  ? 823  GLU A CD  1 
ATOM 5189 O OE1 . GLU A 1 823  ? 167.047 158.918 139.869 1.00 51.28  ? 823  GLU A OE1 1 
ATOM 5190 O OE2 . GLU A 1 823  ? 168.919 157.776 139.777 1.00 50.00  ? 823  GLU A OE2 1 
ATOM 5191 N N   . GLU A 1 824  ? 164.329 156.442 137.241 1.00 50.18  ? 824  GLU A N   1 
ATOM 5192 C CA  . GLU A 1 824  ? 163.643 155.303 136.642 1.00 49.93  ? 824  GLU A CA  1 
ATOM 5193 C C   . GLU A 1 824  ? 162.195 155.628 136.301 1.00 51.32  ? 824  GLU A C   1 
ATOM 5194 O O   . GLU A 1 824  ? 161.662 155.103 135.318 1.00 52.28  ? 824  GLU A O   1 
ATOM 5195 C CB  . GLU A 1 824  ? 163.686 154.090 137.573 1.00 49.62  ? 824  GLU A CB  1 
ATOM 5196 C CG  . GLU A 1 824  ? 165.056 153.746 138.113 1.00 50.96  ? 824  GLU A CG  1 
ATOM 5197 C CD  . GLU A 1 824  ? 165.034 152.514 138.997 1.00 53.27  ? 824  GLU A CD  1 
ATOM 5198 O OE1 . GLU A 1 824  ? 164.043 151.757 138.936 1.00 53.04  ? 824  GLU A OE1 1 
ATOM 5199 O OE2 . GLU A 1 824  ? 166.004 152.304 139.755 1.00 52.10  ? 824  GLU A OE2 1 
ATOM 5200 N N   . VAL A 1 825  ? 161.550 156.482 137.092 1.00 50.48  ? 825  VAL A N   1 
ATOM 5201 C CA  . VAL A 1 825  ? 160.146 156.818 136.889 1.00 52.65  ? 825  VAL A CA  1 
ATOM 5202 C C   . VAL A 1 825  ? 160.049 158.227 136.320 1.00 56.00  ? 825  VAL A C   1 
ATOM 5203 O O   . VAL A 1 825  ? 159.041 158.919 136.505 1.00 55.27  ? 825  VAL A O   1 
ATOM 5204 C CB  . VAL A 1 825  ? 159.347 156.687 138.199 1.00 52.25  ? 825  VAL A CB  1 
ATOM 5205 C CG1 . VAL A 1 825  ? 159.387 155.253 138.692 1.00 49.74  ? 825  VAL A CG1 1 
ATOM 5206 C CG2 . VAL A 1 825  ? 159.896 157.628 139.260 1.00 53.04  ? 825  VAL A CG2 1 
ATOM 5207 N N   . ALA A 1 826  ? 161.100 158.655 135.616 1.00 63.52  ? 826  ALA A N   1 
ATOM 5208 C CA  . ALA A 1 826  ? 161.131 159.992 135.034 1.00 63.11  ? 826  ALA A CA  1 
ATOM 5209 C C   . ALA A 1 826  ? 160.117 160.163 133.914 1.00 64.18  ? 826  ALA A C   1 
ATOM 5210 O O   . ALA A 1 826  ? 159.882 161.294 133.477 1.00 66.68  ? 826  ALA A O   1 
ATOM 5211 C CB  . ALA A 1 826  ? 162.533 160.308 134.513 1.00 61.62  ? 826  ALA A CB  1 
ATOM 5212 N N   . ARG A 1 827  ? 159.524 159.070 133.433 1.00 69.06  ? 827  ARG A N   1 
ATOM 5213 C CA  . ARG A 1 827  ? 158.501 159.178 132.401 1.00 68.19  ? 827  ARG A CA  1 
ATOM 5214 C C   . ARG A 1 827  ? 157.296 159.983 132.876 1.00 68.46  ? 827  ARG A C   1 
ATOM 5215 O O   . ARG A 1 827  ? 156.638 160.646 132.067 1.00 68.00  ? 827  ARG A O   1 
ATOM 5216 C CB  . ARG A 1 827  ? 158.070 157.782 131.949 1.00 69.08  ? 827  ARG A CB  1 
ATOM 5217 C CG  . ARG A 1 827  ? 157.411 156.940 133.034 1.00 69.32  ? 827  ARG A CG  1 
ATOM 5218 C CD  . ARG A 1 827  ? 157.032 155.559 132.514 1.00 69.39  ? 827  ARG A CD  1 
ATOM 5219 N NE  . ARG A 1 827  ? 155.973 155.613 131.513 1.00 70.72  ? 827  ARG A NE  1 
ATOM 5220 C CZ  . ARG A 1 827  ? 155.653 154.609 130.707 1.00 68.85  ? 827  ARG A CZ  1 
ATOM 5221 N NH1 . ARG A 1 827  ? 156.294 153.452 130.757 1.00 68.70  ? 827  ARG A NH1 1 
ATOM 5222 N NH2 . ARG A 1 827  ? 154.669 154.770 129.828 1.00 66.90  ? 827  ARG A NH2 1 
ATOM 5223 N N   . ASP A 1 828  ? 156.982 159.931 134.172 1.00 66.21  ? 828  ASP A N   1 
ATOM 5224 C CA  . ASP A 1 828  ? 155.870 160.692 134.726 1.00 67.05  ? 828  ASP A CA  1 
ATOM 5225 C C   . ASP A 1 828  ? 156.295 162.053 135.262 1.00 67.28  ? 828  ASP A C   1 
ATOM 5226 O O   . ASP A 1 828  ? 155.430 162.877 135.579 1.00 67.04  ? 828  ASP A O   1 
ATOM 5227 C CB  . ASP A 1 828  ? 155.186 159.901 135.850 1.00 65.43  ? 828  ASP A CB  1 
ATOM 5228 C CG  . ASP A 1 828  ? 154.862 158.462 135.456 1.00 68.61  ? 828  ASP A CG  1 
ATOM 5229 O OD1 . ASP A 1 828  ? 154.738 158.162 134.251 1.00 67.47  ? 828  ASP A OD1 1 
ATOM 5230 O OD2 . ASP A 1 828  ? 154.746 157.618 136.371 1.00 66.95  ? 828  ASP A OD2 1 
ATOM 5231 N N   . LEU A 1 829  ? 157.597 162.306 135.371 1.00 61.06  ? 829  LEU A N   1 
ATOM 5232 C CA  . LEU A 1 829  ? 158.139 163.543 135.931 1.00 59.16  ? 829  LEU A CA  1 
ATOM 5233 C C   . LEU A 1 829  ? 158.831 164.334 134.818 1.00 58.49  ? 829  LEU A C   1 
ATOM 5234 O O   . LEU A 1 829  ? 159.921 163.971 134.394 1.00 57.82  ? 829  LEU A O   1 
ATOM 5235 C CB  . LEU A 1 829  ? 159.130 163.218 137.053 1.00 59.51  ? 829  LEU A CB  1 
ATOM 5236 C CG  . LEU A 1 829  ? 158.646 162.912 138.472 1.00 60.30  ? 829  LEU A CG  1 
ATOM 5237 C CD1 . LEU A 1 829  ? 157.971 164.142 139.029 1.00 56.86  ? 829  LEU A CD1 1 
ATOM 5238 C CD2 . LEU A 1 829  ? 157.725 161.699 138.550 1.00 58.32  ? 829  LEU A CD2 1 
ATOM 5239 N N   . PRO A 1 830  ? 158.302 165.372 134.350 1.00 55.99  ? 830  PRO A N   1 
ATOM 5240 C CA  . PRO A 1 830  ? 158.638 165.930 133.060 1.00 54.02  ? 830  PRO A CA  1 
ATOM 5241 C C   . PRO A 1 830  ? 159.935 166.744 133.003 1.00 51.10  ? 830  PRO A C   1 
ATOM 5242 O O   . PRO A 1 830  ? 159.970 167.938 133.362 1.00 51.04  ? 830  PRO A O   1 
ATOM 5243 C CB  . PRO A 1 830  ? 157.371 166.851 133.043 1.00 52.59  ? 830  PRO A CB  1 
ATOM 5244 C CG  . PRO A 1 830  ? 157.332 166.794 135.540 1.00 53.72  ? 830  PRO A CG  1 
ATOM 5245 C CD  . PRO A 1 830  ? 157.466 166.508 134.584 1.00 55.50  ? 830  PRO A CD  1 
ATOM 5246 N N   . GLN A 1 831  ? 161.003 166.105 132.532 1.00 42.51  ? 831  GLN A N   1 
ATOM 5247 C CA  . GLN A 1 831  ? 162.188 166.756 131.972 1.00 38.77  ? 831  GLN A CA  1 
ATOM 5248 C C   . GLN A 1 831  ? 162.825 167.747 132.958 1.00 36.19  ? 831  GLN A C   1 
ATOM 5249 O O   . GLN A 1 831  ? 162.766 168.968 132.795 1.00 39.03  ? 831  GLN A O   1 
ATOM 5250 C CB  . GLN A 1 831  ? 161.831 167.426 130.640 1.00 36.79  ? 831  GLN A CB  1 
ATOM 5251 C CG  . GLN A 1 831  ? 162.992 168.068 129.913 1.00 36.80  ? 831  GLN A CG  1 
ATOM 5252 C CD  . GLN A 1 831  ? 164.053 167.065 129.523 1.00 41.59  ? 831  GLN A CD  1 
ATOM 5253 O OE1 . GLN A 1 831  ? 165.115 166.995 130.140 1.00 43.11  ? 831  GLN A OE1 1 
ATOM 5254 N NE2 . GLN A 1 831  ? 163.772 166.282 128.489 1.00 39.85  ? 831  GLN A NE2 1 
ATOM 5255 N N   . LYS A 1 832  ? 163.399 167.187 134.021 1.00 27.06  ? 832  LYS A N   1 
ATOM 5256 C CA  . LYS A 1 832  ? 164.236 167.966 134.936 1.00 25.31  ? 832  LYS A CA  1 
ATOM 5257 C C   . LYS A 1 832  ? 165.546 168.306 134.234 1.00 28.06  ? 832  LYS A C   1 
ATOM 5258 O O   . LYS A 1 832  ? 166.402 167.442 134.034 1.00 31.53  ? 832  LYS A O   1 
ATOM 5259 C CB  . LYS A 1 832  ? 164.490 167.192 136.224 1.00 28.03  ? 832  LYS A CB  1 
ATOM 5260 C CG  . LYS A 1 832  ? 165.556 167.812 137.116 1.00 24.36  ? 832  LYS A CG  1 
ATOM 5261 C CD  . LYS A 1 832  ? 165.536 167.211 138.512 1.00 28.29  ? 832  LYS A CD  1 
ATOM 5262 C CE  . LYS A 1 832  ? 166.939 166.907 139.019 1.00 29.25  ? 832  LYS A CE  1 
ATOM 5263 N NZ  . LYS A 1 832  ? 167.852 168.082 138.938 1.00 33.50  ? 832  LYS A NZ  1 
ATOM 5264 N N   . ILE A 1 833  ? 165.713 169.572 133.861 1.00 23.02  ? 833  ILE A N   1 
ATOM 5265 C CA  . ILE A 1 833  ? 166.877 170.028 133.109 1.00 16.21  ? 833  ILE A CA  1 
ATOM 5266 C C   . ILE A 1 833  ? 167.852 170.704 134.061 1.00 11.53  ? 833  ILE A C   1 
ATOM 5267 O O   . ILE A 1 833  ? 167.465 171.586 134.836 1.00 20.71  ? 833  ILE A O   1 
ATOM 5268 C CB  . ILE A 1 833  ? 166.471 170.986 131.977 1.00 15.54  ? 833  ILE A CB  1 
ATOM 5269 C CG1 . ILE A 1 833  ? 165.584 170.267 130.964 1.00 20.00  ? 833  ILE A CG1 1 
ATOM 5270 C CG2 . ILE A 1 833  ? 167.702 171.554 131.296 1.00 17.78  ? 833  ILE A CG2 1 
ATOM 5271 C CD1 . ILE A 1 833  ? 164.932 171.190 129.964 1.00 21.89  ? 833  ILE A CD1 1 
ATOM 5272 N N   . GLU A 1 834  ? 169.115 170.291 134.003 1.00 12.82  ? 834  GLU A N   1 
ATOM 5273 C CA  . GLU A 1 834  ? 170.195 170.937 134.741 1.00 11.04  ? 834  GLU A CA  1 
ATOM 5274 C C   . GLU A 1 834  ? 170.923 171.874 133.785 1.00 17.38  ? 834  GLU A C   1 
ATOM 5275 O O   . GLU A 1 834  ? 171.623 171.420 132.874 1.00 18.01  ? 834  GLU A O   1 
ATOM 5276 C CB  . GLU A 1 834  ? 171.147 169.901 135.335 1.00 14.04  ? 834  GLU A CB  1 
ATOM 5277 C CG  . GLU A 1 834  ? 172.259 170.492 136.187 1.00 20.78  ? 834  GLU A CG  1 
ATOM 5278 C CD  . GLU A 1 834  ? 173.151 169.429 136.799 1.00 27.13  ? 834  GLU A CD  1 
ATOM 5279 O OE1 . GLU A 1 834  ? 172.914 168.231 136.541 1.00 25.68  ? 834  GLU A OE1 1 
ATOM 5280 O OE2 . GLU A 1 834  ? 174.091 169.790 137.537 1.00 25.38  ? 834  GLU A OE2 1 
ATOM 5281 N N   . VAL A 1 835  ? 170.756 173.180 133.992 1.00 24.13  ? 835  VAL A N   1 
ATOM 5282 C CA  . VAL A 1 835  ? 171.336 174.166 133.090 1.00 17.49  ? 835  VAL A CA  1 
ATOM 5283 C C   . VAL A 1 835  ? 172.848 174.183 133.260 1.00 19.46  ? 835  VAL A C   1 
ATOM 5284 O O   . VAL A 1 835  ? 173.364 174.252 134.383 1.00 25.11  ? 835  VAL A O   1 
ATOM 5285 C CB  . VAL A 1 835  ? 170.726 175.552 133.348 1.00 13.02  ? 835  VAL A CB  1 
ATOM 5286 C CG1 . VAL A 1 835  ? 171.383 176.596 132.461 1.00 17.95  ? 835  VAL A CG1 1 
ATOM 5287 C CG2 . VAL A 1 835  ? 169.225 175.515 133.115 1.00 10.39  ? 835  VAL A CG2 1 
ATOM 5288 N N   . GLU A 1 836  ? 173.568 174.118 132.140 1.00 19.92  ? 836  GLU A N   1 
ATOM 5289 C CA  . GLU A 1 836  ? 175.022 174.043 132.164 1.00 20.82  ? 836  GLU A CA  1 
ATOM 5290 C C   . GLU A 1 836  ? 175.702 175.398 132.027 1.00 18.62  ? 836  GLU A C   1 
ATOM 5291 O O   . GLU A 1 836  ? 176.867 175.530 132.418 1.00 22.46  ? 836  GLU A O   1 
ATOM 5292 C CB  . GLU A 1 836  ? 175.519 173.121 131.046 1.00 23.59  ? 836  GLU A CB  1 
ATOM 5293 C CG  . GLU A 1 836  ? 174.984 171.700 131.119 1.00 25.26  ? 836  GLU A CG  1 
ATOM 5294 C CD  . GLU A 1 836  ? 175.564 170.915 132.278 1.00 26.38  ? 836  GLU A CD  1 
ATOM 5295 O OE1 . GLU A 1 836  ? 174.782 170.439 133.126 1.00 26.59  ? 836  GLU A OE1 1 
ATOM 5296 O OE2 . GLU A 1 836  ? 176.804 170.777 132.343 1.00 27.06  ? 836  GLU A OE2 1 
ATOM 5297 N N   . SER A 1 837  ? 175.013 176.401 131.477 1.00 15.01  ? 837  SER A N   1 
ATOM 5298 C CA  . SER A 1 837  ? 175.638 177.705 131.276 1.00 14.54  ? 837  SER A CA  1 
ATOM 5299 C C   . SER A 1 837  ? 175.932 178.390 132.604 1.00 21.41  ? 837  SER A C   1 
ATOM 5300 O O   . SER A 1 837  ? 176.963 179.057 132.751 1.00 20.58  ? 837  SER A O   1 
ATOM 5301 C CB  . SER A 1 837  ? 174.746 178.585 130.403 1.00 19.95  ? 837  SER A CB  1 
ATOM 5302 O OG  . SER A 1 837  ? 173.534 178.897 131.067 1.00 27.06  ? 837  SER A OG  1 
ATOM 5303 N N   . CYS A 1 838  ? 175.034 178.243 133.580 1.00 20.68  ? 838  CYS A N   1 
ATOM 5304 C CA  . CYS A 1 838  ? 175.244 178.831 134.897 1.00 11.85  ? 838  CYS A CA  1 
ATOM 5305 C C   . CYS A 1 838  ? 176.453 178.243 135.610 1.00 10.46  ? 838  CYS A C   1 
ATOM 5306 O O   . CYS A 1 838  ? 176.984 178.874 136.529 1.00 17.05  ? 838  CYS A O   1 
ATOM 5307 C CB  . CYS A 1 838  ? 173.998 178.635 135.759 1.00 10.28  ? 838  CYS A CB  1 
ATOM 5308 S SG  . CYS A 1 838  ? 173.815 176.974 136.438 1.00 20.97  ? 838  CYS A SG  1 
ATOM 5309 N N   . LYS A 1 839  ? 176.896 177.056 135.204 1.00 13.00  ? 839  LYS A N   1 
ATOM 5310 C CA  . LYS A 1 839  ? 177.970 176.352 135.888 1.00 11.33  ? 839  LYS A CA  1 
ATOM 5311 C C   . LYS A 1 839  ? 179.353 176.798 135.435 1.00 14.01  ? 839  LYS A C   1 
ATOM 5312 O O   . LYS A 1 839  ? 180.350 176.313 135.981 1.00 23.37  ? 839  LYS A O   1 
ATOM 5313 C CB  . LYS A 1 839  ? 177.806 174.846 135.671 1.00 14.03  ? 839  LYS A CB  1 
ATOM 5314 C CG  . LYS A 1 839  ? 176.588 174.268 136.375 1.00 11.49  ? 839  LYS A CG  1 
ATOM 5315 C CD  . LYS A 1 839  ? 176.406 172.791 136.083 1.00 14.02  ? 839  LYS A CD  1 
ATOM 5316 C CE  . LYS A 1 839  ? 177.477 171.963 136.761 1.00 23.80  ? 839  LYS A CE  1 
ATOM 5317 N NZ  . LYS A 1 839  ? 177.318 171.998 138.237 1.00 21.06  ? 839  LYS A NZ  1 
ATOM 5318 N N   . GLN A 1 840  ? 179.437 177.704 134.464 1.00 11.82  ? 840  GLN A N   1 
ATOM 5319 C CA  . GLN A 1 840  ? 180.705 178.174 133.916 1.00 17.84  ? 840  GLN A CA  1 
ATOM 5320 C C   . GLN A 1 840  ? 180.912 179.666 134.166 1.00 19.76  ? 840  GLN A C   1 
ATOM 5321 O O   . GLN A 1 840  ? 181.387 180.396 133.294 1.00 27.58  ? 840  GLN A O   1 
ATOM 5322 C CB  . GLN A 1 840  ? 180.792 177.872 132.422 1.00 17.54  ? 840  GLN A CB  1 
ATOM 5323 C CG  . GLN A 1 840  ? 180.416 176.448 132.032 1.00 16.40  ? 840  GLN A CG  1 
ATOM 5324 C CD  . GLN A 1 840  ? 181.206 175.396 132.788 1.00 24.31  ? 840  GLN A CD  1 
ATOM 5325 O OE1 . GLN A 1 840  ? 182.389 175.576 133.077 1.00 25.49  ? 840  GLN A OE1 1 
ATOM 5326 N NE2 . GLN A 1 840  ? 180.553 174.284 133.107 1.00 19.99  ? 840  GLN A NE2 1 
ATOM 5327 N N   . LEU A 1 841  ? 180.553 180.138 135.356 1.00 9.61   ? 841  LEU A N   1 
ATOM 5328 C CA  . LEU A 1 841  ? 180.788 181.528 135.716 1.00 12.01  ? 841  LEU A CA  1 
ATOM 5329 C C   . LEU A 1 841  ? 182.242 181.726 136.130 1.00 17.50  ? 841  LEU A C   1 
ATOM 5330 O O   . LEU A 1 841  ? 182.901 180.805 136.616 1.00 23.43  ? 841  LEU A O   1 
ATOM 5331 C CB  . LEU A 1 841  ? 179.849 181.955 136.843 1.00 14.31  ? 841  LEU A CB  1 
ATOM 5332 C CG  . LEU A 1 841  ? 178.360 181.980 136.493 1.00 7.86   ? 841  LEU A CG  1 
ATOM 5333 C CD1 . LEU A 1 841  ? 177.518 182.205 137.737 1.00 10.51  ? 841  LEU A CD1 1 
ATOM 5334 C CD2 . LEU A 1 841  ? 178.068 183.039 135.443 1.00 13.73  ? 841  LEU A CD2 1 
ATOM 5335 N N   . THR A 1 842  ? 182.742 182.943 135.931 1.00 18.58  ? 842  THR A N   1 
ATOM 5336 C CA  . THR A 1 842  ? 184.150 183.255 136.132 1.00 23.05  ? 842  THR A CA  1 
ATOM 5337 C C   . THR A 1 842  ? 184.328 184.218 137.299 1.00 23.58  ? 842  THR A C   1 
ATOM 5338 O O   . THR A 1 842  ? 183.504 185.113 137.506 1.00 25.17  ? 842  THR A O   1 
ATOM 5339 C CB  . THR A 1 842  ? 184.760 183.869 134.868 1.00 23.99  ? 842  THR A CB  1 
ATOM 5340 O OG1 . THR A 1 842  ? 184.085 185.094 134.559 1.00 26.55  ? 842  THR A OG1 1 
ATOM 5341 C CG2 . THR A 1 842  ? 184.620 182.916 133.694 1.00 22.68  ? 842  THR A CG2 1 
ATOM 5342 N N   . LEU A 1 843  ? 185.408 184.028 138.059 1.00 20.66  ? 843  LEU A N   1 
ATOM 5343 C CA  . LEU A 1 843  ? 185.734 184.963 139.127 1.00 22.09  ? 843  LEU A CA  1 
ATOM 5344 C C   . LEU A 1 843  ? 185.991 186.353 138.564 1.00 29.47  ? 843  LEU A C   1 
ATOM 5345 O O   . LEU A 1 843  ? 186.610 186.512 137.509 1.00 33.04  ? 843  LEU A O   1 
ATOM 5346 C CB  . LEU A 1 843  ? 186.970 184.506 139.905 1.00 27.19  ? 843  LEU A CB  1 
ATOM 5347 C CG  . LEU A 1 843  ? 186.880 183.410 140.964 1.00 29.05  ? 843  LEU A CG  1 
ATOM 5348 C CD1 . LEU A 1 843  ? 188.269 183.047 141.413 1.00 26.99  ? 843  LEU A CD1 1 
ATOM 5349 C CD2 . LEU A 1 843  ? 186.053 183.858 142.154 1.00 24.56  ? 843  LEU A CD2 1 
ATOM 5350 N N   . SER A 1 844  ? 185.509 187.363 139.278 1.00 28.60  ? 844  SER A N   1 
ATOM 5351 C CA  . SER A 1 844  ? 185.971 188.715 139.031 1.00 28.03  ? 844  SER A CA  1 
ATOM 5352 C C   . SER A 1 844  ? 187.393 188.868 139.557 1.00 33.18  ? 844  SER A C   1 
ATOM 5353 O O   . SER A 1 844  ? 187.878 188.058 140.351 1.00 34.45  ? 844  SER A O   1 
ATOM 5354 C CB  . SER A 1 844  ? 185.044 189.733 139.692 1.00 34.73  ? 844  SER A CB  1 
ATOM 5355 O OG  . SER A 1 844  ? 183.749 189.683 139.122 1.00 37.72  ? 844  SER A OG  1 
ATOM 5356 N N   . GLY A 1 845  ? 188.072 189.916 139.092 1.00 36.80  ? 845  GLY A N   1 
ATOM 5357 C CA  . GLY A 1 845  ? 189.433 190.150 139.548 1.00 37.14  ? 845  GLY A CA  1 
ATOM 5358 C C   . GLY A 1 845  ? 189.509 190.393 141.043 1.00 36.83  ? 845  GLY A C   1 
ATOM 5359 O O   . GLY A 1 845  ? 190.335 189.800 141.743 1.00 35.60  ? 845  GLY A O   1 
ATOM 5360 N N   . VAL A 1 846  ? 188.632 191.257 141.557 1.00 33.59  ? 846  VAL A N   1 
ATOM 5361 C CA  . VAL A 1 846  ? 188.666 191.594 142.976 1.00 33.69  ? 846  VAL A CA  1 
ATOM 5362 C C   . VAL A 1 846  ? 188.200 190.415 143.828 1.00 38.29  ? 846  VAL A C   1 
ATOM 5363 O O   . VAL A 1 846  ? 188.782 190.130 144.882 1.00 41.07  ? 846  VAL A O   1 
ATOM 5364 C CB  . VAL A 1 846  ? 187.846 192.873 143.236 1.00 39.65  ? 846  VAL A CB  1 
ATOM 5365 C CG1 . VAL A 1 846  ? 188.270 193.966 142.264 1.00 39.11  ? 846  VAL A CG1 1 
ATOM 5366 C CG2 . VAL A 1 846  ? 186.354 192.610 143.100 1.00 39.49  ? 846  VAL A CG2 1 
ATOM 5367 N N   . GLN A 1 847  ? 187.161 189.702 143.382 1.00 34.43  ? 847  GLN A N   1 
ATOM 5368 C CA  . GLN A 1 847  ? 186.735 188.487 144.069 1.00 31.79  ? 847  GLN A CA  1 
ATOM 5369 C C   . GLN A 1 847  ? 187.872 187.482 144.142 1.00 31.28  ? 847  GLN A C   1 
ATOM 5370 O O   . GLN A 1 847  ? 188.098 186.848 145.180 1.00 36.90  ? 847  GLN A O   1 
ATOM 5371 C CB  . GLN A 1 847  ? 185.545 187.877 143.330 1.00 28.31  ? 847  GLN A CB  1 
ATOM 5372 C CG  . GLN A 1 847  ? 184.643 186.984 144.143 1.00 28.48  ? 847  GLN A CG  1 
ATOM 5373 C CD  . GLN A 1 847  ? 183.635 186.270 143.270 1.00 23.58  ? 847  GLN A CD  1 
ATOM 5374 O OE1 . GLN A 1 847  ? 183.692 186.367 142.047 1.00 30.05  ? 847  GLN A OE1 1 
ATOM 5375 N NE2 . GLN A 1 847  ? 182.701 185.562 143.888 1.00 21.79  ? 847  GLN A NE2 1 
ATOM 5376 N N   . LYS A 1 848  ? 188.595 187.331 143.035 1.00 32.89  ? 848  LYS A N   1 
ATOM 5377 C CA  . LYS A 1 848  ? 189.706 186.394 142.959 1.00 33.12  ? 848  LYS A CA  1 
ATOM 5378 C C   . LYS A 1 848  ? 190.829 186.779 143.911 1.00 37.29  ? 848  LYS A C   1 
ATOM 5379 O O   . LYS A 1 848  ? 191.370 185.923 144.625 1.00 38.15  ? 848  LYS A O   1 
ATOM 5380 C CB  . LYS A 1 848  ? 190.209 186.353 141.520 1.00 35.77  ? 848  LYS A CB  1 
ATOM 5381 C CG  . LYS A 1 848  ? 191.308 185.368 141.242 1.00 36.03  ? 848  LYS A CG  1 
ATOM 5382 C CD  . LYS A 1 848  ? 191.664 185.405 139.769 1.00 37.17  ? 848  LYS A CD  1 
ATOM 5383 C CE  . LYS A 1 848  ? 192.697 184.364 139.430 1.00 38.00  ? 848  LYS A CE  1 
ATOM 5384 N NZ  . LYS A 1 848  ? 194.019 184.657 140.054 1.00 39.20  ? 848  LYS A NZ  1 
ATOM 5385 N N   . GLN A 1 849  ? 191.212 188.060 143.918 1.00 40.23  ? 849  GLN A N   1 
ATOM 5386 C CA  . GLN A 1 849  ? 192.240 188.506 144.851 1.00 39.02  ? 849  GLN A CA  1 
ATOM 5387 C C   . GLN A 1 849  ? 191.795 188.287 146.288 1.00 37.05  ? 849  GLN A C   1 
ATOM 5388 O O   . GLN A 1 849  ? 192.603 187.918 147.146 1.00 39.84  ? 849  GLN A O   1 
ATOM 5389 C CB  . GLN A 1 849  ? 192.590 189.980 144.618 1.00 37.45  ? 849  GLN A CB  1 
ATOM 5390 C CG  . GLN A 1 849  ? 193.275 190.284 143.289 1.00 41.83  ? 849  GLN A CG  1 
ATOM 5391 C CD  . GLN A 1 849  ? 193.585 191.765 143.108 1.00 45.21  ? 849  GLN A CD  1 
ATOM 5392 O OE1 . GLN A 1 849  ? 193.234 192.597 143.945 1.00 43.47  ? 849  GLN A OE1 1 
ATOM 5393 N NE2 . GLN A 1 849  ? 194.251 192.096 142.007 1.00 43.36  ? 849  GLN A NE2 1 
ATOM 5394 N N   . LEU A 1 850  ? 190.506 188.493 146.565 1.00 35.81  ? 850  LEU A N   1 
ATOM 5395 C CA  . LEU A 1 850  ? 189.991 188.253 147.908 1.00 34.44  ? 850  LEU A CA  1 
ATOM 5396 C C   . LEU A 1 850  ? 190.087 186.779 148.287 1.00 36.84  ? 850  LEU A C   1 
ATOM 5397 O O   . LEU A 1 850  ? 190.436 186.447 149.423 1.00 40.40  ? 850  LEU A O   1 
ATOM 5398 C CB  . LEU A 1 850  ? 188.551 188.747 148.005 1.00 33.69  ? 850  LEU A CB  1 
ATOM 5399 C CG  . LEU A 1 850  ? 187.912 188.615 149.383 1.00 36.11  ? 850  LEU A CG  1 
ATOM 5400 C CD1 . LEU A 1 850  ? 188.675 189.463 150.377 1.00 36.91  ? 850  LEU A CD1 1 
ATOM 5401 C CD2 . LEU A 1 850  ? 186.454 189.029 149.327 1.00 35.02  ? 850  LEU A CD2 1 
ATOM 5402 N N   . TYR A 1 851  ? 189.781 185.880 147.350 1.00 40.13  ? 851  TYR A N   1 
ATOM 5403 C CA  . TYR A 1 851  ? 189.909 184.458 147.639 1.00 36.93  ? 851  TYR A CA  1 
ATOM 5404 C C   . TYR A 1 851  ? 191.346 184.040 147.895 1.00 41.38  ? 851  TYR A C   1 
ATOM 5405 O O   . TYR A 1 851  ? 191.632 183.294 148.841 1.00 42.60  ? 851  TYR A O   1 
ATOM 5406 N N   . LEU A 1 852  ? 192.271 184.517 147.059 1.00 45.17  ? 852  LEU A N   1 
ATOM 5407 C CA  . LEU A 1 852  ? 193.681 184.201 147.269 1.00 44.28  ? 852  LEU A CA  1 
ATOM 5408 C C   . LEU A 1 852  ? 194.182 184.769 148.590 1.00 46.27  ? 852  LEU A C   1 
ATOM 5409 O O   . LEU A 1 852  ? 194.950 184.114 149.304 1.00 48.45  ? 852  LEU A O   1 
ATOM 5410 C CB  . LEU A 1 852  ? 194.526 184.716 146.104 1.00 43.26  ? 852  LEU A CB  1 
ATOM 5411 C CG  . LEU A 1 852  ? 194.090 184.294 144.701 1.00 45.21  ? 852  LEU A CG  1 
ATOM 5412 C CD1 . LEU A 1 852  ? 195.125 184.710 143.672 1.00 43.77  ? 852  LEU A CD1 1 
ATOM 5413 C CD2 . LEU A 1 852  ? 193.865 182.795 144.657 1.00 44.80  ? 852  LEU A CD2 1 
ATOM 5414 N N   . SER A 1 853  ? 193.753 185.985 148.938 1.00 45.06  ? 853  SER A N   1 
ATOM 5415 C CA  . SER A 1 853  ? 194.121 186.559 150.226 1.00 44.49  ? 853  SER A CA  1 
ATOM 5416 C C   . SER A 1 853  ? 193.537 185.749 151.375 1.00 47.90  ? 853  SER A C   1 
ATOM 5417 O O   . SER A 1 853  ? 194.179 185.587 152.415 1.00 51.50  ? 853  SER A O   1 
ATOM 5418 C CB  . SER A 1 853  ? 193.658 188.014 150.305 1.00 45.81  ? 853  SER A CB  1 
ATOM 5419 O OG  . SER A 1 853  ? 194.324 188.811 149.343 1.00 47.66  ? 853  SER A OG  1 
ATOM 5420 N N   . SER A 1 854  ? 192.313 185.244 151.211 1.00 44.72  ? 854  SER A N   1 
ATOM 5421 C CA  . SER A 1 854  ? 191.718 184.384 152.227 1.00 42.64  ? 854  SER A CA  1 
ATOM 5422 C C   . SER A 1 854  ? 192.591 183.166 152.481 1.00 45.47  ? 854  SER A C   1 
ATOM 5423 O O   . SER A 1 854  ? 192.927 182.850 153.631 1.00 46.38  ? 854  SER A O   1 
ATOM 5424 C CB  . SER A 1 854  ? 190.324 183.949 151.784 1.00 42.27  ? 854  SER A CB  1 
ATOM 5425 O OG  . SER A 1 854  ? 189.466 185.065 151.681 1.00 41.18  ? 854  SER A OG  1 
ATOM 5426 N N   . VAL A 1 855  ? 192.974 182.475 151.407 1.00 51.46  ? 855  VAL A N   1 
ATOM 5427 C CA  . VAL A 1 855  ? 193.813 181.289 151.555 1.00 50.70  ? 855  VAL A CA  1 
ATOM 5428 C C   . VAL A 1 855  ? 195.150 181.658 152.188 1.00 53.37  ? 855  VAL A C   1 
ATOM 5429 O O   . VAL A 1 855  ? 195.649 180.957 153.079 1.00 54.44  ? 855  VAL A O   1 
ATOM 5430 C CB  . VAL A 1 855  ? 193.998 180.589 150.196 1.00 51.61  ? 855  VAL A CB  1 
ATOM 5431 C CG1 . VAL A 1 855  ? 194.568 179.193 150.393 1.00 52.47  ? 855  VAL A CG1 1 
ATOM 5432 C CG2 . VAL A 1 855  ? 192.676 180.521 149.452 1.00 50.49  ? 855  VAL A CG2 1 
ATOM 5433 N N   . ALA A 1 856  ? 195.745 182.772 151.747 1.00 57.04  ? 856  ALA A N   1 
ATOM 5434 C CA  . ALA A 1 856  ? 197.048 183.178 152.262 1.00 57.71  ? 856  ALA A CA  1 
ATOM 5435 C C   . ALA A 1 856  ? 196.992 183.498 153.752 1.00 60.21  ? 856  ALA A C   1 
ATOM 5436 O O   . ALA A 1 856  ? 197.848 183.046 154.520 1.00 63.09  ? 856  ALA A O   1 
ATOM 5437 C CB  . ALA A 1 856  ? 197.570 184.380 151.476 1.00 57.57  ? 856  ALA A CB  1 
ATOM 5438 N N   . ASN A 1 857  ? 195.996 184.279 154.180 1.00 58.52  ? 857  ASN A N   1 
ATOM 5439 C CA  . ASN A 1 857  ? 195.877 184.613 155.595 1.00 57.14  ? 857  ASN A CA  1 
ATOM 5440 C C   . ASN A 1 857  ? 195.578 183.379 156.435 1.00 59.11  ? 857  ASN A C   1 
ATOM 5441 O O   . ASN A 1 857  ? 196.101 183.243 157.547 1.00 60.89  ? 857  ASN A O   1 
ATOM 5442 C CB  . ASN A 1 857  ? 194.806 185.682 155.817 1.00 58.17  ? 857  ASN A CB  1 
ATOM 5443 C CG  . ASN A 1 857  ? 195.147 187.006 155.158 1.00 61.95  ? 857  ASN A CG  1 
ATOM 5444 O OD1 . ASN A 1 857  ? 194.467 187.450 154.235 1.00 60.04  ? 857  ASN A OD1 1 
ATOM 5445 N ND2 . ASN A 1 857  ? 196.211 187.644 155.633 1.00 62.36  ? 857  ASN A ND2 1 
ATOM 5446 N N   . TRP A 1 858  ? 194.733 182.472 155.934 1.00 60.38  ? 858  TRP A N   1 
ATOM 5447 C CA  . TRP A 1 858  ? 194.450 181.265 156.703 1.00 60.23  ? 858  TRP A CA  1 
ATOM 5448 C C   . TRP A 1 858  ? 195.705 180.422 156.876 1.00 62.06  ? 858  TRP A C   1 
ATOM 5449 O O   . TRP A 1 858  ? 195.977 179.924 157.972 1.00 63.98  ? 858  TRP A O   1 
ATOM 5450 C CB  . TRP A 1 858  ? 193.351 180.443 156.038 1.00 60.42  ? 858  TRP A CB  1 
ATOM 5451 C CG  . TRP A 1 858  ? 193.053 179.178 156.783 1.00 58.77  ? 858  TRP A CG  1 
ATOM 5452 C CD1 . TRP A 1 858  ? 192.251 179.043 157.878 1.00 59.22  ? 858  TRP A CD1 1 
ATOM 5453 C CD2 . TRP A 1 858  ? 193.579 177.874 156.508 1.00 57.48  ? 858  TRP A CD2 1 
ATOM 5454 N NE1 . TRP A 1 858  ? 192.231 177.734 158.292 1.00 58.56  ? 858  TRP A NE1 1 
ATOM 5455 C CE2 . TRP A 1 858  ? 193.039 176.996 157.467 1.00 59.09  ? 858  TRP A CE2 1 
ATOM 5456 C CE3 . TRP A 1 858  ? 194.447 177.364 155.539 1.00 58.32  ? 858  TRP A CE3 1 
ATOM 5457 C CZ2 . TRP A 1 858  ? 193.340 175.636 157.487 1.00 60.27  ? 858  TRP A CZ2 1 
ATOM 5458 C CZ3 . TRP A 1 858  ? 194.744 176.014 155.560 1.00 60.71  ? 858  TRP A CZ3 1 
ATOM 5459 C CH2 . TRP A 1 858  ? 194.192 175.166 156.528 1.00 61.09  ? 858  TRP A CH2 1 
ATOM 5460 N N   . GLN A 1 859  ? 196.491 180.262 155.808 1.00 65.04  ? 859  GLN A N   1 
ATOM 5461 C CA  . GLN A 1 859  ? 197.731 179.499 155.917 1.00 67.12  ? 859  GLN A CA  1 
ATOM 5462 C C   . GLN A 1 859  ? 198.730 180.191 156.839 1.00 68.79  ? 859  GLN A C   1 
ATOM 5463 O O   . GLN A 1 859  ? 199.438 179.526 157.606 1.00 67.41  ? 859  GLN A O   1 
ATOM 5464 C CB  . GLN A 1 859  ? 198.334 179.278 154.530 1.00 65.75  ? 859  GLN A CB  1 
ATOM 5465 C CG  . GLN A 1 859  ? 197.496 178.378 153.635 1.00 66.64  ? 859  GLN A CG  1 
ATOM 5466 C CD  . GLN A 1 859  ? 198.104 178.189 152.260 1.00 68.05  ? 859  GLN A CD  1 
ATOM 5467 O OE1 . GLN A 1 859  ? 199.131 178.785 151.935 1.00 67.80  ? 859  GLN A OE1 1 
ATOM 5468 N NE2 . GLN A 1 859  ? 197.471 177.356 151.443 1.00 66.90  ? 859  GLN A NE2 1 
ATOM 5469 N N   . GLN A 1 860  ? 198.803 181.522 156.777 1.00 71.98  ? 860  GLN A N   1 
ATOM 5470 C CA  . GLN A 1 860  ? 199.710 182.262 157.648 1.00 72.15  ? 860  GLN A CA  1 
ATOM 5471 C C   . GLN A 1 860  ? 199.335 182.080 159.114 1.00 72.49  ? 860  GLN A C   1 
ATOM 5472 O O   . GLN A 1 860  ? 200.205 181.881 159.970 1.00 73.07  ? 860  GLN A O   1 
ATOM 5473 C CB  . GLN A 1 860  ? 199.701 183.744 157.270 1.00 71.61  ? 860  GLN A CB  1 
ATOM 5474 C CG  . GLN A 1 860  ? 200.680 184.597 158.058 1.00 72.37  ? 860  GLN A CG  1 
ATOM 5475 C CD  . GLN A 1 860  ? 200.677 186.046 157.610 1.00 73.90  ? 860  GLN A CD  1 
ATOM 5476 O OE1 . GLN A 1 860  ? 199.913 186.432 156.726 1.00 73.45  ? 860  GLN A OE1 1 
ATOM 5477 N NE2 . GLN A 1 860  ? 201.533 186.856 158.221 1.00 73.50  ? 860  GLN A NE2 1 
ATOM 5478 N N   . GLN A 1 861  ? 198.038 182.146 159.424 1.00 74.24  ? 861  GLN A N   1 
ATOM 5479 C CA  . GLN A 1 861  ? 197.606 181.951 160.803 1.00 75.14  ? 861  GLN A CA  1 
ATOM 5480 C C   . GLN A 1 861  ? 197.772 180.502 161.244 1.00 74.61  ? 861  GLN A C   1 
ATOM 5481 O O   . GLN A 1 861  ? 198.026 180.243 162.426 1.00 74.31  ? 861  GLN A O   1 
ATOM 5482 C CB  . GLN A 1 861  ? 196.155 182.400 160.970 1.00 74.57  ? 861  GLN A CB  1 
ATOM 5483 C CG  . GLN A 1 861  ? 195.948 183.892 160.759 1.00 73.91  ? 861  GLN A CG  1 
ATOM 5484 C CD  . GLN A 1 861  ? 196.702 184.735 161.769 1.00 75.90  ? 861  GLN A CD  1 
ATOM 5485 O OE1 . GLN A 1 861  ? 197.682 185.399 161.432 1.00 76.09  ? 861  GLN A OE1 1 
ATOM 5486 N NE2 . GLN A 1 861  ? 196.245 184.715 163.016 1.00 75.58  ? 861  GLN A NE2 1 
ATOM 5487 N N   . GLN A 1 862  ? 197.626 179.549 160.320 1.00 72.80  ? 862  GLN A N   1 
ATOM 5488 C CA  . GLN A 1 862  ? 197.878 178.152 160.658 1.00 73.96  ? 862  GLN A CA  1 
ATOM 5489 C C   . GLN A 1 862  ? 199.349 177.923 160.983 1.00 75.72  ? 862  GLN A C   1 
ATOM 5490 O O   . GLN A 1 862  ? 199.677 177.168 161.906 1.00 75.65  ? 862  GLN A O   1 
ATOM 5491 C CB  . GLN A 1 862  ? 197.432 177.244 159.511 1.00 73.32  ? 862  GLN A CB  1 
ATOM 5492 C CG  . GLN A 1 862  ? 195.931 177.249 159.241 1.00 74.08  ? 862  GLN A CG  1 
ATOM 5493 C CD  . GLN A 1 862  ? 195.106 176.739 160.407 1.00 74.05  ? 862  GLN A CD  1 
ATOM 5494 O OE1 . GLN A 1 862  ? 194.405 177.503 161.074 1.00 72.28  ? 862  GLN A OE1 1 
ATOM 5495 N NE2 . GLN A 1 862  ? 195.183 175.438 160.656 1.00 73.09  ? 862  GLN A NE2 1 
ATOM 5496 N N   . ALA A 1 863  ? 200.249 178.560 160.229 1.00 82.59  ? 863  ALA A N   1 
ATOM 5497 C CA  . ALA A 1 863  ? 201.674 178.450 160.527 1.00 82.35  ? 863  ALA A CA  1 
ATOM 5498 C C   . ALA A 1 863  ? 202.004 179.070 161.879 1.00 82.06  ? 863  ALA A C   1 
ATOM 5499 O O   . ALA A 1 863  ? 202.800 178.518 162.647 1.00 81.33  ? 863  ALA A O   1 
ATOM 5500 C CB  . ALA A 1 863  ? 202.496 179.106 159.418 1.00 80.75  ? 863  ALA A CB  1 
ATOM 5501 N N   . LEU A 1 864  ? 201.403 180.215 162.186 1.00 82.56  ? 864  LEU A N   1 
ATOM 5502 C CA  . LEU A 1 864  ? 201.631 180.885 163.462 1.00 82.15  ? 864  LEU A CA  1 
ATOM 5503 C C   . LEU A 1 864  ? 200.993 180.107 164.608 1.00 82.27  ? 864  LEU A C   1 
ATOM 5504 O O   . LEU A 1 864  ? 200.291 180.677 165.443 1.00 82.45  ? 864  LEU A O   1 
ATOM 5505 C CB  . LEU A 1 864  ? 201.080 182.314 163.426 1.00 82.31  ? 864  LEU A CB  1 
ATOM 5506 C CG  . LEU A 1 864  ? 202.054 183.439 163.067 1.00 82.54  ? 864  LEU A CG  1 
ATOM 5507 C CD1 . LEU A 1 864  ? 202.722 183.188 161.722 1.00 81.49  ? 864  LEU A CD1 1 
ATOM 5508 C CD2 . LEU A 1 864  ? 201.342 184.784 163.071 1.00 82.32  ? 864  LEU A CD2 1 
ATOM 5509 N N   . GLY A 1 874  ? 188.717 175.904 162.579 1.00 51.19  ? 874  GLY A N   1 
ATOM 5510 C CA  . GLY A 1 874  ? 189.588 176.686 161.722 1.00 52.04  ? 874  GLY A CA  1 
ATOM 5511 C C   . GLY A 1 874  ? 189.305 176.485 160.246 1.00 54.94  ? 874  GLY A C   1 
ATOM 5512 O O   . GLY A 1 874  ? 189.183 177.449 159.491 1.00 53.92  ? 874  GLY A O   1 
ATOM 5513 N N   . MET A 1 875  ? 189.207 175.219 159.833 1.00 54.86  ? 875  MET A N   1 
ATOM 5514 C CA  . MET A 1 875  ? 188.894 174.920 158.440 1.00 52.69  ? 875  MET A CA  1 
ATOM 5515 C C   . MET A 1 875  ? 187.453 175.277 158.099 1.00 49.12  ? 875  MET A C   1 
ATOM 5516 O O   . MET A 1 875  ? 187.168 175.678 156.963 1.00 46.31  ? 875  MET A O   1 
ATOM 5517 C CB  . MET A 1 875  ? 189.163 173.445 158.146 1.00 50.30  ? 875  MET A CB  1 
ATOM 5518 C CG  . MET A 1 875  ? 189.204 173.106 156.668 1.00 49.51  ? 875  MET A CG  1 
ATOM 5519 S SD  . MET A 1 875  ? 190.547 173.933 155.797 1.00 59.76  ? 875  MET A SD  1 
ATOM 5520 C CE  . MET A 1 875  ? 190.528 173.043 154.245 1.00 50.78  ? 875  MET A CE  1 
ATOM 5521 N N   . LEU A 1 876  ? 186.537 175.138 159.062 1.00 47.52  ? 876  LEU A N   1 
ATOM 5522 C CA  . LEU A 1 876  ? 185.155 175.544 158.827 1.00 46.04  ? 876  LEU A CA  1 
ATOM 5523 C C   . LEU A 1 876  ? 185.074 177.024 158.487 1.00 47.74  ? 876  LEU A C   1 
ATOM 5524 O O   . LEU A 1 876  ? 184.333 177.419 157.581 1.00 51.77  ? 876  LEU A O   1 
ATOM 5525 C CB  . LEU A 1 876  ? 184.287 175.245 160.051 1.00 47.92  ? 876  LEU A CB  1 
ATOM 5526 C CG  . LEU A 1 876  ? 183.699 173.849 160.289 1.00 48.86  ? 876  LEU A CG  1 
ATOM 5527 C CD1 . LEU A 1 876  ? 182.717 173.464 159.186 1.00 46.10  ? 876  LEU A CD1 1 
ATOM 5528 C CD2 . LEU A 1 876  ? 184.777 172.795 160.475 1.00 49.02  ? 876  LEU A CD2 1 
ATOM 5529 N N   . GLY A 1 877  ? 185.827 177.858 159.206 1.00 41.79  ? 877  GLY A N   1 
ATOM 5530 C CA  . GLY A 1 877  ? 185.811 179.283 158.926 1.00 40.00  ? 877  GLY A CA  1 
ATOM 5531 C C   . GLY A 1 877  ? 186.342 179.617 157.545 1.00 39.55  ? 877  GLY A C   1 
ATOM 5532 O O   . GLY A 1 877  ? 185.763 180.439 156.830 1.00 41.57  ? 877  GLY A O   1 
ATOM 5533 N N   . LEU A 1 878  ? 187.450 178.983 157.150 1.00 34.64  ? 878  LEU A N   1 
ATOM 5534 C CA  . LEU A 1 878  ? 187.992 179.220 155.816 1.00 35.68  ? 878  LEU A CA  1 
ATOM 5535 C C   . LEU A 1 878  ? 187.010 178.791 154.737 1.00 34.77  ? 878  LEU A C   1 
ATOM 5536 O O   . LEU A 1 878  ? 186.785 179.523 153.765 1.00 38.34  ? 878  LEU A O   1 
ATOM 5537 C CB  . LEU A 1 878  ? 189.317 178.481 155.636 1.00 39.15  ? 878  LEU A CB  1 
ATOM 5538 C CG  . LEU A 1 878  ? 189.844 178.534 154.198 1.00 34.31  ? 878  LEU A CG  1 
ATOM 5539 C CD1 . LEU A 1 878  ? 190.533 179.860 153.919 1.00 35.12  ? 878  LEU A CD1 1 
ATOM 5540 C CD2 . LEU A 1 878  ? 190.766 177.364 153.897 1.00 36.79  ? 878  LEU A CD2 1 
ATOM 5541 N N   . LEU A 1 879  ? 186.416 177.605 154.887 1.00 32.49  ? 879  LEU A N   1 
ATOM 5542 C CA  . LEU A 1 879  ? 185.474 177.129 153.881 1.00 29.10  ? 879  LEU A CA  1 
ATOM 5543 C C   . LEU A 1 879  ? 184.242 178.021 153.814 1.00 31.60  ? 879  LEU A C   1 
ATOM 5544 O O   . LEU A 1 879  ? 183.758 178.337 152.721 1.00 32.95  ? 879  LEU A O   1 
ATOM 5545 C CB  . LEU A 1 879  ? 185.088 175.679 154.169 1.00 29.18  ? 879  LEU A CB  1 
ATOM 5546 C CG  . LEU A 1 879  ? 186.203 174.661 153.920 1.00 31.83  ? 879  LEU A CG  1 
ATOM 5547 C CD1 . LEU A 1 879  ? 185.654 173.248 153.920 1.00 31.50  ? 879  LEU A CD1 1 
ATOM 5548 C CD2 . LEU A 1 879  ? 186.922 174.957 152.614 1.00 28.28  ? 879  LEU A CD2 1 
ATOM 5549 N N   . HIS A 1 880  ? 183.736 178.459 154.969 1.00 27.57  ? 880  HIS A N   1 
ATOM 5550 C CA  . HIS A 1 880  ? 182.586 179.355 154.988 1.00 23.81  ? 880  HIS A CA  1 
ATOM 5551 C C   . HIS A 1 880  ? 182.905 180.690 154.332 1.00 24.12  ? 880  HIS A C   1 
ATOM 5552 O O   . HIS A 1 880  ? 182.083 181.233 153.585 1.00 31.03  ? 880  HIS A O   1 
ATOM 5553 C CB  . HIS A 1 880  ? 182.114 179.570 156.425 1.00 28.86  ? 880  HIS A CB  1 
ATOM 5554 C CG  . HIS A 1 880  ? 180.899 180.438 156.537 1.00 36.54  ? 880  HIS A CG  1 
ATOM 5555 N ND1 . HIS A 1 880  ? 180.908 181.649 157.196 1.00 34.65  ? 880  HIS A ND1 1 
ATOM 5556 C CD2 . HIS A 1 880  ? 179.639 180.272 156.071 1.00 32.56  ? 880  HIS A CD2 1 
ATOM 5557 C CE1 . HIS A 1 880  ? 179.705 182.190 157.133 1.00 29.84  ? 880  HIS A CE1 1 
ATOM 5558 N NE2 . HIS A 1 880  ? 178.916 181.375 156.456 1.00 29.95  ? 880  HIS A NE2 1 
ATOM 5559 N N   . ARG A 1 881  ? 184.090 181.243 154.592 1.00 20.88  ? 881  ARG A N   1 
ATOM 5560 C CA  . ARG A 1 881  ? 184.378 182.562 154.043 1.00 18.39  ? 881  ARG A CA  1 
ATOM 5561 C C   . ARG A 1 881  ? 184.668 182.476 152.550 1.00 20.70  ? 881  ARG A C   1 
ATOM 5562 O O   . ARG A 1 881  ? 184.307 183.383 151.797 1.00 25.07  ? 881  ARG A O   1 
ATOM 5563 C CB  . ARG A 1 881  ? 185.527 183.222 154.807 1.00 24.88  ? 881  ARG A CB  1 
ATOM 5564 C CG  . ARG A 1 881  ? 185.829 184.653 154.363 1.00 27.85  ? 881  ARG A CG  1 
ATOM 5565 C CD  . ARG A 1 881  ? 186.921 185.291 155.220 1.00 26.57  ? 881  ARG A CD  1 
ATOM 5566 N NE  . ARG A 1 881  ? 187.245 186.646 154.785 1.00 28.36  ? 881  ARG A NE  1 
ATOM 5567 C CZ  . ARG A 1 881  ? 188.147 187.429 155.366 1.00 33.97  ? 881  ARG A CZ  1 
ATOM 5568 N NH1 . ARG A 1 881  ? 188.837 187.027 156.423 1.00 33.11  ? 881  ARG A NH1 1 
ATOM 5569 N NH2 . ARG A 1 881  ? 188.360 188.647 154.877 1.00 28.78  ? 881  ARG A NH2 1 
ATOM 5570 N N   . LEU A 1 882  ? 185.281 181.377 152.096 1.00 26.98  ? 882  LEU A N   1 
ATOM 5571 C CA  . LEU A 1 882  ? 185.418 181.149 150.659 1.00 20.37  ? 882  LEU A CA  1 
ATOM 5572 C C   . LEU A 1 882  ? 184.056 180.985 149.995 1.00 15.17  ? 882  LEU A C   1 
ATOM 5573 O O   . LEU A 1 882  ? 183.833 181.483 148.884 1.00 18.18  ? 882  LEU A O   1 
ATOM 5574 C CB  . LEU A 1 882  ? 186.289 179.921 150.396 1.00 15.61  ? 882  LEU A CB  1 
ATOM 5575 C CG  . LEU A 1 882  ? 187.796 180.075 150.586 1.00 15.40  ? 882  LEU A CG  1 
ATOM 5576 C CD1 . LEU A 1 882  ? 188.525 178.877 150.008 1.00 19.26  ? 882  LEU A CD1 1 
ATOM 5577 C CD2 . LEU A 1 882  ? 188.282 181.358 149.939 1.00 21.55  ? 882  LEU A CD2 1 
ATOM 5578 N N   . LYS A 1 883  ? 183.138 180.279 150.657 1.00 16.60  ? 883  LYS A N   1 
ATOM 5579 C CA  . LYS A 1 883  ? 181.772 180.166 150.161 1.00 15.57  ? 883  LYS A CA  1 
ATOM 5580 C C   . LYS A 1 883  ? 181.117 181.536 150.043 1.00 21.57  ? 883  LYS A C   1 
ATOM 5581 O O   . LYS A 1 883  ? 180.387 181.805 149.082 1.00 21.51  ? 883  LYS A O   1 
ATOM 5582 C CB  . LYS A 1 883  ? 180.970 179.259 151.092 1.00 14.45  ? 883  LYS A CB  1 
ATOM 5583 C CG  . LYS A 1 883  ? 179.585 178.891 150.609 1.00 15.80  ? 883  LYS A CG  1 
ATOM 5584 C CD  . LYS A 1 883  ? 178.878 178.059 151.663 1.00 13.81  ? 883  LYS A CD  1 
ATOM 5585 C CE  . LYS A 1 883  ? 177.378 178.050 151.462 1.00 20.11  ? 883  LYS A CE  1 
ATOM 5586 N NZ  . LYS A 1 883  ? 176.707 177.209 152.487 1.00 20.81  ? 883  LYS A NZ  1 
ATOM 5587 N N   . LEU A 1 884  ? 181.359 182.410 151.021 1.00 23.16  ? 884  LEU A N   1 
ATOM 5588 C CA  . LEU A 1 884  ? 180.816 183.764 150.961 1.00 16.54  ? 884  LEU A CA  1 
ATOM 5589 C C   . LEU A 1 884  ? 181.430 184.566 149.818 1.00 16.97  ? 884  LEU A C   1 
ATOM 5590 O O   . LEU A 1 884  ? 180.716 185.272 149.097 1.00 22.34  ? 884  LEU A O   1 
ATOM 5591 C CB  . LEU A 1 884  ? 181.038 184.476 152.293 1.00 17.72  ? 884  LEU A CB  1 
ATOM 5592 C CG  . LEU A 1 884  ? 180.063 184.141 153.419 1.00 23.84  ? 884  LEU A CG  1 
ATOM 5593 C CD1 . LEU A 1 884  ? 180.563 184.708 154.735 1.00 25.82  ? 884  LEU A CD1 1 
ATOM 5594 C CD2 . LEU A 1 884  ? 178.682 184.678 153.093 1.00 23.14  ? 884  LEU A CD2 1 
ATOM 5595 N N   . ILE A 1 885  ? 182.752 184.479 149.642 1.00 14.73  ? 885  ILE A N   1 
ATOM 5596 C CA  . ILE A 1 885  ? 183.405 185.215 148.559 1.00 14.87  ? 885  ILE A CA  1 
ATOM 5597 C C   . ILE A 1 885  ? 182.871 184.760 147.212 1.00 17.53  ? 885  ILE A C   1 
ATOM 5598 O O   . ILE A 1 885  ? 182.580 185.580 146.332 1.00 28.85  ? 885  ILE A O   1 
ATOM 5599 C CB  . ILE A 1 885  ? 184.937 185.063 148.624 1.00 20.40  ? 885  ILE A CB  1 
ATOM 5600 C CG1 . ILE A 1 885  ? 185.490 185.533 149.967 1.00 23.80  ? 885  ILE A CG1 1 
ATOM 5601 C CG2 . ILE A 1 885  ? 185.598 185.823 147.486 1.00 23.78  ? 885  ILE A CG2 1 
ATOM 5602 C CD1 . ILE A 1 885  ? 186.660 184.715 150.440 1.00 24.13  ? 885  ILE A CD1 1 
ATOM 5603 N N   . CYS A 1 886  ? 182.741 183.447 147.023 1.00 15.71  ? 886  CYS A N   1 
ATOM 5604 C CA  . CYS A 1 886  ? 182.220 182.941 145.760 1.00 13.91  ? 886  CYS A CA  1 
ATOM 5605 C C   . CYS A 1 886  ? 180.790 183.407 145.526 1.00 10.34  ? 886  CYS A C   1 
ATOM 5606 O O   . CYS A 1 886  ? 180.451 183.860 144.427 1.00 15.04  ? 886  CYS A O   1 
ATOM 5607 C CB  . CYS A 1 886  ? 182.307 181.418 145.736 1.00 21.12  ? 886  CYS A CB  1 
ATOM 5608 S SG  . CYS A 1 886  ? 183.988 180.764 145.604 1.00 23.87  ? 886  CYS A SG  1 
ATOM 5609 N N   . ALA A 1 887  ? 179.946 183.341 146.559 1.00 17.63  ? 887  ALA A N   1 
ATOM 5610 C CA  . ALA A 1 887  ? 178.536 183.682 146.395 1.00 17.62  ? 887  ALA A CA  1 
ATOM 5611 C C   . ALA A 1 887  ? 178.343 185.185 146.235 1.00 17.54  ? 887  ALA A C   1 
ATOM 5612 O O   . ALA A 1 887  ? 177.874 185.657 145.193 1.00 19.26  ? 887  ALA A O   1 
ATOM 5613 C CB  . ALA A 1 887  ? 177.730 183.157 147.583 1.00 12.31  ? 887  ALA A CB  1 
ATOM 5614 N N   . HIS A 1 888  ? 178.703 185.955 147.260 1.00 17.98  ? 888  HIS A N   1 
ATOM 5615 C CA  . HIS A 1 888  ? 178.535 187.404 147.219 1.00 15.03  ? 888  HIS A CA  1 
ATOM 5616 C C   . HIS A 1 888  ? 179.763 188.050 147.892 1.00 19.42  ? 888  HIS A C   1 
ATOM 5617 O O   . HIS A 1 888  ? 179.869 188.036 149.104 1.00 21.87  ? 888  HIS A O   1 
ATOM 5618 C CB  . HIS A 1 888  ? 177.250 187.843 147.922 1.00 18.37  ? 888  HIS A CB  1 
ATOM 5619 C CG  . HIS A 1 888  ? 176.610 189.044 147.296 1.00 24.37  ? 888  HIS A CG  1 
ATOM 5620 N ND1 . HIS A 1 888  ? 177.215 190.282 147.270 1.00 27.87  ? 888  HIS A ND1 1 
ATOM 5621 C CD2 . HIS A 1 888  ? 175.412 189.198 146.685 1.00 24.06  ? 888  HIS A CD2 1 
ATOM 5622 C CE1 . HIS A 1 888  ? 176.419 191.146 146.667 1.00 26.76  ? 888  HIS A CE1 1 
ATOM 5623 N NE2 . HIS A 1 888  ? 175.318 190.514 146.303 1.00 25.93  ? 888  HIS A NE2 1 
ATOM 5624 N N   . PRO A 1 889  ? 180.692 188.597 147.082 1.00 22.16  ? 889  PRO A N   1 
ATOM 5625 C CA  . PRO A 1 889  ? 181.851 189.258 147.716 1.00 26.54  ? 889  PRO A CA  1 
ATOM 5626 C C   . PRO A 1 889  ? 181.485 190.428 148.652 1.00 26.31  ? 889  PRO A C   1 
ATOM 5627 O O   . PRO A 1 889  ? 182.223 190.689 149.620 1.00 29.35  ? 889  PRO A O   1 
ATOM 5628 C CB  . PRO A 1 889  ? 182.675 189.764 146.543 1.00 27.14  ? 889  PRO A CB  1 
ATOM 5629 C CG  . PRO A 1 889  ? 182.318 188.857 145.416 1.00 24.72  ? 889  PRO A CG  1 
ATOM 5630 C CD  . PRO A 1 889  ? 180.865 188.529 145.647 1.00 20.36  ? 889  PRO A CD  1 
ATOM 5631 N N   . ALA A 1 890  ? 180.399 191.155 148.379 1.00 28.98  ? 890  ALA A N   1 
ATOM 5632 C CA  . ALA A 1 890  ? 180.087 192.362 149.139 1.00 29.30  ? 890  ALA A CA  1 
ATOM 5633 C C   . ALA A 1 890  ? 179.803 192.061 150.604 1.00 30.10  ? 890  ALA A C   1 
ATOM 5634 O O   . ALA A 1 890  ? 180.007 192.928 151.462 1.00 33.85  ? 890  ALA A O   1 
ATOM 5635 C CB  . ALA A 1 890  ? 178.899 193.086 148.508 1.00 32.33  ? 890  ALA A CB  1 
ATOM 5636 N N   . ILE A 1 891  ? 179.324 190.855 150.912 1.00 27.93  ? 891  ILE A N   1 
ATOM 5637 C CA  . ILE A 1 891  ? 179.099 190.484 152.304 1.00 24.24  ? 891  ILE A CA  1 
ATOM 5638 C C   . ILE A 1 891  ? 180.415 190.427 153.068 1.00 25.56  ? 891  ILE A C   1 
ATOM 5639 O O   . ILE A 1 891  ? 180.518 190.928 154.194 1.00 32.01  ? 891  ILE A O   1 
ATOM 5640 C CB  . ILE A 1 891  ? 178.342 189.147 152.383 1.00 23.49  ? 891  ILE A CB  1 
ATOM 5641 C CG1 . ILE A 1 891  ? 176.955 189.282 151.752 1.00 18.48  ? 891  ILE A CG1 1 
ATOM 5642 C CG2 . ILE A 1 891  ? 178.259 188.675 153.818 1.00 23.53  ? 891  ILE A CG2 1 
ATOM 5643 C CD1 . ILE A 1 891  ? 176.251 187.965 151.555 1.00 20.15  ? 891  ILE A CD1 1 
ATOM 5644 N N   . VAL A 1 892  ? 181.440 189.814 152.473 1.00 29.36  ? 892  VAL A N   1 
ATOM 5645 C CA  . VAL A 1 892  ? 182.736 189.716 153.138 1.00 28.07  ? 892  VAL A CA  1 
ATOM 5646 C C   . VAL A 1 892  ? 183.350 191.098 153.318 1.00 31.29  ? 892  VAL A C   1 
ATOM 5647 O O   . VAL A 1 892  ? 183.830 191.448 154.402 1.00 34.55  ? 892  VAL A O   1 
ATOM 5648 C CB  . VAL A 1 892  ? 183.672 188.783 152.349 1.00 28.75  ? 892  VAL A CB  1 
ATOM 5649 C CG1 . VAL A 1 892  ? 185.035 188.722 153.010 1.00 29.51  ? 892  VAL A CG1 1 
ATOM 5650 C CG2 . VAL A 1 892  ? 183.065 187.400 152.243 1.00 25.75  ? 892  VAL A CG2 1 
ATOM 5651 N N   . ASN A 1 893  ? 183.339 191.906 152.260 1.00 34.69  ? 893  ASN A N   1 
ATOM 5652 C CA  . ASN A 1 893  ? 183.845 193.273 152.311 1.00 40.35  ? 893  ASN A CA  1 
ATOM 5653 C C   . ASN A 1 893  ? 182.835 194.180 151.621 1.00 45.50  ? 893  ASN A C   1 
ATOM 5654 O O   . ASN A 1 893  ? 182.585 194.014 150.410 1.00 44.82  ? 893  ASN A O   1 
ATOM 5655 C CB  . ASN A 1 893  ? 185.219 193.386 151.651 1.00 42.01  ? 893  ASN A CB  1 
ATOM 5656 C CG  . ASN A 1 893  ? 186.278 192.579 152.369 1.00 46.80  ? 893  ASN A CG  1 
ATOM 5657 O OD1 . ASN A 1 893  ? 186.816 191.618 151.823 1.00 47.84  ? 893  ASN A OD1 1 
ATOM 5658 N ND2 . ASN A 1 893  ? 186.586 192.967 153.601 1.00 44.97  ? 893  ASN A ND2 1 
ATOM 5659 N N   . PRO A 1 894  ? 182.230 195.131 152.330 1.00 49.75  ? 894  PRO A N   1 
ATOM 5660 C CA  . PRO A 1 894  ? 181.251 196.031 151.708 1.00 49.08  ? 894  PRO A CA  1 
ATOM 5661 C C   . PRO A 1 894  ? 181.853 197.108 150.819 1.00 50.33  ? 894  PRO A C   1 
ATOM 5662 O O   . PRO A 1 894  ? 181.150 198.066 150.482 1.00 51.65  ? 894  PRO A O   1 
ATOM 5663 C CB  . PRO A 1 894  ? 180.558 196.666 152.924 1.00 48.36  ? 894  PRO A CB  1 
ATOM 5664 C CG  . PRO A 1 894  ? 180.748 195.682 154.024 1.00 49.87  ? 894  PRO A CG  1 
ATOM 5665 C CD  . PRO A 1 894  ? 182.103 195.096 153.794 1.00 47.16  ? 894  PRO A CD  1 
ATOM 5666 N N   . GLU A 1 895  ? 183.121 196.981 150.438 1.00 53.82  ? 895  GLU A N   1 
ATOM 5667 C CA  . GLU A 1 895  ? 183.789 198.001 149.667 1.00 55.73  ? 895  GLU A CA  1 
ATOM 5668 C C   . GLU A 1 895  ? 183.169 198.121 148.283 1.00 56.63  ? 895  GLU A C   1 
ATOM 5669 O O   . GLU A 1 895  ? 182.611 197.169 147.739 1.00 56.93  ? 895  GLU A O   1 
ATOM 5670 C CB  . GLU A 1 895  ? 185.283 197.697 149.567 1.00 54.91  ? 895  GLU A CB  1 
ATOM 5671 C CG  . GLU A 1 895  ? 186.005 197.796 150.897 1.00 54.91  ? 895  GLU A CG  1 
ATOM 5672 C CD  . GLU A 1 895  ? 187.478 197.470 150.787 1.00 57.19  ? 895  GLU A CD  1 
ATOM 5673 O OE1 . GLU A 1 895  ? 187.913 197.045 149.699 1.00 57.93  ? 895  GLU A OE1 1 
ATOM 5674 O OE2 . GLU A 1 895  ? 188.200 197.633 151.793 1.00 55.48  ? 895  GLU A OE2 1 
ATOM 5675 N N   . PRO A 1 896  ? 183.262 199.306 147.692 1.00 57.24  ? 896  PRO A N   1 
ATOM 5676 C CA  . PRO A 1 896  ? 182.646 199.553 146.372 1.00 55.55  ? 896  PRO A CA  1 
ATOM 5677 C C   . PRO A 1 896  ? 183.020 198.538 145.301 1.00 55.57  ? 896  PRO A C   1 
ATOM 5678 O O   . PRO A 1 896  ? 182.221 198.299 144.386 1.00 55.20  ? 896  PRO A O   1 
ATOM 5679 C CB  . PRO A 1 896  ? 183.171 200.951 146.005 1.00 56.44  ? 896  PRO A CB  1 
ATOM 5680 C CG  . PRO A 1 896  ? 183.481 201.582 147.380 1.00 56.74  ? 896  PRO A CG  1 
ATOM 5681 C CD  . PRO A 1 896  ? 183.970 200.475 148.232 1.00 56.02  ? 896  PRO A CD  1 
ATOM 5682 N N   . ARG A 1 897  ? 184.208 197.934 145.384 1.00 54.98  ? 897  ARG A N   1 
ATOM 5683 C CA  . ARG A 1 897  ? 184.660 197.030 144.330 1.00 53.78  ? 897  ARG A CA  1 
ATOM 5684 C C   . ARG A 1 897  ? 183.756 195.809 144.211 1.00 53.54  ? 897  ARG A C   1 
ATOM 5685 O O   . ARG A 1 897  ? 183.458 195.355 143.100 1.00 52.68  ? 897  ARG A O   1 
ATOM 5686 C CB  . ARG A 1 897  ? 186.104 196.599 144.589 1.00 52.37  ? 897  ARG A CB  1 
ATOM 5687 C CG  . ARG A 1 897  ? 187.077 197.752 144.753 1.00 52.33  ? 897  ARG A CG  1 
ATOM 5688 C CD  . ARG A 1 897  ? 188.522 197.276 144.688 1.00 52.40  ? 897  ARG A CD  1 
ATOM 5689 N NE  . ARG A 1 897  ? 188.794 196.182 145.612 1.00 52.17  ? 897  ARG A NE  1 
ATOM 5690 C CZ  . ARG A 1 897  ? 188.824 196.306 146.932 1.00 53.81  ? 897  ARG A CZ  1 
ATOM 5691 N NH1 . ARG A 1 897  ? 188.586 197.465 147.523 1.00 51.00  ? 897  ARG A NH1 1 
ATOM 5692 N NH2 . ARG A 1 897  ? 189.104 195.242 147.678 1.00 53.96  ? 897  ARG A NH2 1 
ATOM 5693 N N   . PHE A 1 898  ? 183.311 195.264 145.341 1.00 47.46  ? 898  PHE A N   1 
ATOM 5694 C CA  . PHE A 1 898  ? 182.613 193.985 145.347 1.00 46.85  ? 898  PHE A CA  1 
ATOM 5695 C C   . PHE A 1 898  ? 181.113 194.090 145.095 1.00 45.42  ? 898  PHE A C   1 
ATOM 5696 O O   . PHE A 1 898  ? 180.487 193.063 144.811 1.00 44.56  ? 898  PHE A O   1 
ATOM 5697 C CB  . PHE A 1 898  ? 182.861 193.274 146.677 1.00 44.81  ? 898  PHE A CB  1 
ATOM 5698 C CG  . PHE A 1 898  ? 184.312 193.172 147.043 1.00 44.41  ? 898  PHE A CG  1 
ATOM 5699 C CD1 . PHE A 1 898  ? 184.844 193.949 148.056 1.00 45.91  ? 898  PHE A CD1 1 
ATOM 5700 C CD2 . PHE A 1 898  ? 185.145 192.296 146.370 1.00 46.12  ? 898  PHE A CD2 1 
ATOM 5701 C CE1 . PHE A 1 898  ? 186.181 193.854 148.388 1.00 47.01  ? 898  PHE A CE1 1 
ATOM 5702 C CE2 . PHE A 1 898  ? 186.480 192.195 146.699 1.00 47.57  ? 898  PHE A CE2 1 
ATOM 5703 C CZ  . PHE A 1 898  ? 186.998 192.972 147.710 1.00 48.82  ? 898  PHE A CZ  1 
ATOM 5704 N N   . ARG A 1 899  ? 180.513 195.279 145.191 1.00 49.86  ? 899  ARG A N   1 
ATOM 5705 C CA  . ARG A 1 899  ? 179.069 195.368 144.988 1.00 54.04  ? 899  ARG A CA  1 
ATOM 5706 C C   . ARG A 1 899  ? 178.691 195.116 143.533 1.00 53.87  ? 899  ARG A C   1 
ATOM 5707 O O   . ARG A 1 899  ? 177.696 194.437 143.255 1.00 52.47  ? 899  ARG A O   1 
ATOM 5708 C CB  . ARG A 1 899  ? 178.536 196.727 145.446 1.00 54.92  ? 899  ARG A CB  1 
ATOM 5709 C CG  . ARG A 1 899  ? 178.589 196.962 146.947 1.00 53.87  ? 899  ARG A CG  1 
ATOM 5710 C CD  . ARG A 1 899  ? 177.848 198.238 147.327 1.00 53.73  ? 899  ARG A CD  1 
ATOM 5711 N NE  . ARG A 1 899  ? 178.453 199.443 146.769 1.00 54.91  ? 899  ARG A NE  1 
ATOM 5712 C CZ  . ARG A 1 899  ? 179.414 200.143 147.356 1.00 54.49  ? 899  ARG A CZ  1 
ATOM 5713 N NH1 . ARG A 1 899  ? 179.922 199.778 148.522 1.00 52.85  ? 899  ARG A NH1 1 
ATOM 5714 N NH2 . ARG A 1 899  ? 179.874 201.240 146.760 1.00 53.93  ? 899  ARG A NH2 1 
ATOM 5715 N N   . ASP A 1 900  ? 179.466 195.654 142.594 1.00 48.93  ? 900  ASP A N   1 
ATOM 5716 C CA  . ASP A 1 900  ? 179.156 195.542 141.176 1.00 48.91  ? 900  ASP A CA  1 
ATOM 5717 C C   . ASP A 1 900  ? 179.959 194.462 140.462 1.00 48.47  ? 900  ASP A C   1 
ATOM 5718 O O   . ASP A 1 900  ? 179.820 194.312 139.244 1.00 49.05  ? 900  ASP A O   1 
ATOM 5719 C CB  . ASP A 1 900  ? 179.370 196.895 140.482 1.00 50.76  ? 900  ASP A CB  1 
ATOM 5720 C CG  . ASP A 1 900  ? 180.815 197.367 140.538 1.00 53.58  ? 900  ASP A CG  1 
ATOM 5721 O OD1 . ASP A 1 900  ? 181.660 196.677 141.147 1.00 53.37  ? 900  ASP A OD1 1 
ATOM 5722 O OD2 . ASP A 1 900  ? 181.107 198.440 139.970 1.00 51.21  ? 900  ASP A OD2 1 
ATOM 5723 N N   . ASN A 1 901  ? 180.787 193.708 141.180 1.00 41.72  ? 901  ASN A N   1 
ATOM 5724 C CA  . ASN A 1 901  ? 181.645 192.691 140.586 1.00 40.97  ? 901  ASN A CA  1 
ATOM 5725 C C   . ASN A 1 901  ? 181.350 191.312 141.162 1.00 40.29  ? 901  ASN A C   1 
ATOM 5726 O O   . ASN A 1 901  ? 182.259 190.555 141.510 1.00 39.94  ? 901  ASN A O   1 
ATOM 5727 C CB  . ASN A 1 901  ? 183.118 193.049 140.769 1.00 41.41  ? 901  ASN A CB  1 
ATOM 5728 C CG  . ASN A 1 901  ? 183.513 194.292 139.998 1.00 42.88  ? 901  ASN A CG  1 
ATOM 5729 O OD1 . ASN A 1 901  ? 183.043 194.520 138.884 1.00 39.46  ? 901  ASN A OD1 1 
ATOM 5730 N ND2 . ASN A 1 901  ? 184.380 195.106 140.589 1.00 43.15  ? 901  ASN A ND2 1 
ATOM 5731 N N   . SER A 1 902  ? 180.066 190.966 141.271 1.00 28.62  ? 902  SER A N   1 
ATOM 5732 C CA  . SER A 1 902  ? 179.653 189.644 141.721 1.00 22.27  ? 902  SER A CA  1 
ATOM 5733 C C   . SER A 1 902  ? 179.125 188.860 140.528 1.00 20.22  ? 902  SER A C   1 
ATOM 5734 O O   . SER A 1 902  ? 178.022 189.139 140.052 1.00 25.70  ? 902  SER A O   1 
ATOM 5735 C CB  . SER A 1 902  ? 178.590 189.750 142.812 1.00 18.88  ? 902  SER A CB  1 
ATOM 5736 O OG  . SER A 1 902  ? 178.043 188.477 143.107 1.00 22.82  ? 902  SER A OG  1 
ATOM 5737 N N   . PRO A 1 903  ? 179.874 187.902 140.002 1.00 15.85  ? 903  PRO A N   1 
ATOM 5738 C CA  . PRO A 1 903  ? 179.397 187.145 138.830 1.00 14.19  ? 903  PRO A CA  1 
ATOM 5739 C C   . PRO A 1 903  ? 178.124 186.372 139.085 1.00 11.42  ? 903  PRO A C   1 
ATOM 5740 O O   . PRO A 1 903  ? 177.279 186.288 138.191 1.00 18.33  ? 903  PRO A O   1 
ATOM 5741 C CB  . PRO A 1 903  ? 180.586 186.212 138.520 1.00 21.16  ? 903  PRO A CB  1 
ATOM 5742 C CG  . PRO A 1 903  ? 181.527 186.366 139.666 1.00 17.55  ? 903  PRO A CG  1 
ATOM 5743 C CD  . PRO A 1 903  ? 181.310 187.700 140.258 1.00 18.41  ? 903  PRO A CD  1 
ATOM 5744 N N   . LYS A 1 904  ? 177.951 185.819 140.287 1.00 7.82   ? 904  LYS A N   1 
ATOM 5745 C CA  . LYS A 1 904  ? 176.711 185.111 140.596 1.00 3.80   ? 904  LYS A CA  1 
ATOM 5746 C C   . LYS A 1 904  ? 175.525 186.064 140.647 1.00 11.65  ? 904  LYS A C   1 
ATOM 5747 O O   . LYS A 1 904  ? 174.449 185.746 140.132 1.00 18.20  ? 904  LYS A O   1 
ATOM 5748 C CB  . LYS A 1 904  ? 176.857 184.351 141.911 1.00 6.83   ? 904  LYS A CB  1 
ATOM 5749 C CG  . LYS A 1 904  ? 177.817 183.186 141.826 1.00 11.43  ? 904  LYS A CG  1 
ATOM 5750 C CD  . LYS A 1 904  ? 178.003 182.505 143.166 1.00 12.89  ? 904  LYS A CD  1 
ATOM 5751 C CE  . LYS A 1 904  ? 176.792 181.730 143.625 1.00 5.93   ? 904  LYS A CE  1 
ATOM 5752 N NZ  . LYS A 1 904  ? 176.542 180.548 142.782 1.00 6.89   ? 904  LYS A NZ  1 
ATOM 5753 N N   . LEU A 1 905  ? 175.699 187.241 141.253 1.00 10.28  ? 905  LEU A N   1 
ATOM 5754 C CA  . LEU A 1 905  ? 174.604 188.206 141.303 1.00 4.24   ? 905  LEU A CA  1 
ATOM 5755 C C   . LEU A 1 905  ? 174.278 188.751 139.918 1.00 15.07  ? 905  LEU A C   1 
ATOM 5756 O O   . LEU A 1 905  ? 173.101 188.908 139.567 1.00 23.32  ? 905  LEU A O   1 
ATOM 5757 C CB  . LEU A 1 905  ? 174.947 189.348 142.257 1.00 11.75  ? 905  LEU A CB  1 
ATOM 5758 C CG  . LEU A 1 905  ? 173.823 190.364 142.464 1.00 14.95  ? 905  LEU A CG  1 
ATOM 5759 C CD1 . LEU A 1 905  ? 172.615 189.703 143.109 1.00 7.92   ? 905  LEU A CD1 1 
ATOM 5760 C CD2 . LEU A 1 905  ? 174.303 191.543 143.291 1.00 13.79  ? 905  LEU A CD2 1 
ATOM 5761 N N   . ASN A 1 906  ? 175.305 189.053 139.120 1.00 10.17  ? 906  ASN A N   1 
ATOM 5762 C CA  . ASN A 1 906  ? 175.067 189.510 137.756 1.00 7.42   ? 906  ASN A CA  1 
ATOM 5763 C C   . ASN A 1 906  ? 174.341 188.447 136.946 1.00 10.97  ? 906  ASN A C   1 
ATOM 5764 O O   . ASN A 1 906  ? 173.380 188.749 136.226 1.00 20.23  ? 906  ASN A O   1 
ATOM 5765 C CB  . ASN A 1 906  ? 176.390 189.878 137.085 1.00 11.15  ? 906  ASN A CB  1 
ATOM 5766 C CG  . ASN A 1 906  ? 177.006 191.135 137.658 1.00 16.01  ? 906  ASN A CG  1 
ATOM 5767 O OD1 . ASN A 1 906  ? 176.373 191.856 138.428 1.00 19.41  ? 906  ASN A OD1 1 
ATOM 5768 N ND2 . ASN A 1 906  ? 178.249 191.407 137.283 1.00 18.63  ? 906  ASN A ND2 1 
ATOM 5769 N N   . TRP A 1 907  ? 174.777 187.191 137.065 1.00 9.72   ? 907  TRP A N   1 
ATOM 5770 C CA  . TRP A 1 907  ? 174.122 186.104 136.351 1.00 9.00   ? 907  TRP A CA  1 
ATOM 5771 C C   . TRP A 1 907  ? 172.681 185.941 136.810 1.00 5.51   ? 907  TRP A C   1 
ATOM 5772 O O   . TRP A 1 907  ? 171.788 185.685 135.995 1.00 12.52  ? 907  TRP A O   1 
ATOM 5773 C CB  . TRP A 1 907  ? 174.903 184.803 136.550 1.00 10.00  ? 907  TRP A CB  1 
ATOM 5774 C CG  . TRP A 1 907  ? 174.092 183.563 136.312 1.00 8.40   ? 907  TRP A CG  1 
ATOM 5775 C CD1 . TRP A 1 907  ? 174.000 182.863 135.147 1.00 8.49   ? 907  TRP A CD1 1 
ATOM 5776 C CD2 . TRP A 1 907  ? 173.266 182.873 137.259 1.00 7.18   ? 907  TRP A CD2 1 
ATOM 5777 N NE1 . TRP A 1 907  ? 173.164 181.787 135.306 1.00 9.38   ? 907  TRP A NE1 1 
ATOM 5778 C CE2 . TRP A 1 907  ? 172.700 181.772 136.594 1.00 5.15   ? 907  TRP A CE2 1 
ATOM 5779 C CE3 . TRP A 1 907  ? 172.949 183.082 138.604 1.00 8.77   ? 907  TRP A CE3 1 
ATOM 5780 C CZ2 . TRP A 1 907  ? 171.838 180.884 137.224 1.00 3.65   ? 907  TRP A CZ2 1 
ATOM 5781 C CZ3 . TRP A 1 907  ? 172.086 182.208 139.223 1.00 10.37  ? 907  TRP A CZ3 1 
ATOM 5782 C CH2 . TRP A 1 907  ? 171.544 181.119 138.534 1.00 5.74   ? 907  TRP A CH2 1 
ATOM 5783 N N   . LEU A 1 908  ? 172.436 186.078 138.115 1.00 2.25   ? 908  LEU A N   1 
ATOM 5784 C CA  . LEU A 1 908  ? 171.086 185.927 138.641 1.00 3.72   ? 908  LEU A CA  1 
ATOM 5785 C C   . LEU A 1 908  ? 170.170 187.011 138.100 1.00 8.84   ? 908  LEU A C   1 
ATOM 5786 O O   . LEU A 1 908  ? 169.053 186.732 137.652 1.00 15.20  ? 908  LEU A O   1 
ATOM 5787 C CB  . LEU A 1 908  ? 171.116 185.958 140.169 1.00 5.28   ? 908  LEU A CB  1 
ATOM 5788 C CG  . LEU A 1 908  ? 169.756 186.015 140.865 1.00 5.84   ? 908  LEU A CG  1 
ATOM 5789 C CD1 . LEU A 1 908  ? 169.025 184.695 140.702 1.00 3.20   ? 908  LEU A CD1 1 
ATOM 5790 C CD2 . LEU A 1 908  ? 169.909 186.372 142.332 1.00 3.58   ? 908  LEU A CD2 1 
ATOM 5791 N N   . LEU A 1 909  ? 170.632 188.260 138.126 1.00 11.29  ? 909  LEU A N   1 
ATOM 5792 C CA  . LEU A 1 909  ? 169.813 189.347 137.605 1.00 7.96   ? 909  LEU A CA  1 
ATOM 5793 C C   . LEU A 1 909  ? 169.557 189.169 136.115 1.00 12.11  ? 909  LEU A C   1 
ATOM 5794 O O   . LEU A 1 909  ? 168.437 189.390 135.637 1.00 15.08  ? 909  LEU A O   1 
ATOM 5795 C CB  . LEU A 1 909  ? 170.484 190.687 137.896 1.00 8.07   ? 909  LEU A CB  1 
ATOM 5796 C CG  . LEU A 1 909  ? 170.457 191.051 139.382 1.00 1.86   ? 909  LEU A CG  1 
ATOM 5797 C CD1 . LEU A 1 909  ? 171.391 192.212 139.682 1.00 8.16   ? 909  LEU A CD1 1 
ATOM 5798 C CD2 . LEU A 1 909  ? 169.038 191.351 139.842 1.00 6.97   ? 909  LEU A CD2 1 
ATOM 5799 N N   . LYS A 1 910  ? 170.577 188.735 135.369 1.00 13.06  ? 910  LYS A N   1 
ATOM 5800 C CA  . LYS A 1 910  ? 170.416 188.518 133.935 1.00 12.25  ? 910  LYS A CA  1 
ATOM 5801 C C   . LYS A 1 910  ? 169.392 187.423 133.646 1.00 11.91  ? 910  LYS A C   1 
ATOM 5802 O O   . LYS A 1 910  ? 168.504 187.594 132.800 1.00 21.45  ? 910  LYS A O   1 
ATOM 5803 C CB  . LYS A 1 910  ? 171.770 188.177 133.319 1.00 9.60   ? 910  LYS A CB  1 
ATOM 5804 C CG  . LYS A 1 910  ? 171.767 188.027 131.812 1.00 19.60  ? 910  LYS A CG  1 
ATOM 5805 C CD  . LYS A 1 910  ? 173.187 187.926 131.280 1.00 21.76  ? 910  LYS A CD  1 
ATOM 5806 C CE  . LYS A 1 910  ? 174.093 187.196 132.259 1.00 19.20  ? 910  LYS A CE  1 
ATOM 5807 N NZ  . LYS A 1 910  ? 173.807 185.736 132.290 1.00 16.22  ? 910  LYS A NZ  1 
ATOM 5808 N N   . ILE A 1 911  ? 169.487 186.289 134.348 1.00 5.62   ? 911  ILE A N   1 
ATOM 5809 C CA  . ILE A 1 911  ? 168.548 185.210 134.062 1.00 5.58   ? 911  ILE A CA  1 
ATOM 5810 C C   . ILE A 1 911  ? 167.147 185.590 134.503 1.00 15.06  ? 911  ILE A C   1 
ATOM 5811 O O   . ILE A 1 911  ? 166.176 185.200 133.858 1.00 23.95  ? 911  ILE A O   1 
ATOM 5812 C CB  . ILE A 1 911  ? 168.945 183.875 134.714 1.00 8.04   ? 911  ILE A CB  1 
ATOM 5813 C CG1 . ILE A 1 911  ? 168.908 183.999 136.230 1.00 10.17  ? 911  ILE A CG1 1 
ATOM 5814 C CG2 . ILE A 1 911  ? 170.310 183.423 134.236 1.00 14.69  ? 911  ILE A CG2 1 
ATOM 5815 C CD1 . ILE A 1 911  ? 168.878 182.703 136.922 1.00 12.49  ? 911  ILE A CD1 1 
ATOM 5816 N N   . LEU A 1 912  ? 167.002 186.304 135.625 1.00 11.94  ? 912  LEU A N   1 
ATOM 5817 C CA  . LEU A 1 912  ? 165.665 186.698 136.050 1.00 4.34   ? 912  LEU A CA  1 
ATOM 5818 C C   . LEU A 1 912  ? 165.049 187.674 135.061 1.00 10.41  ? 912  LEU A C   1 
ATOM 5819 O O   . LEU A 1 912  ? 163.847 187.608 134.786 1.00 16.35  ? 912  LEU A O   1 
ATOM 5820 C CB  . LEU A 1 912  ? 165.695 187.292 137.457 1.00 9.05   ? 912  LEU A CB  1 
ATOM 5821 C CG  . LEU A 1 912  ? 166.147 186.382 138.600 1.00 5.26   ? 912  LEU A CG  1 
ATOM 5822 C CD1 . LEU A 1 912  ? 166.395 187.199 139.854 1.00 7.08   ? 912  LEU A CD1 1 
ATOM 5823 C CD2 . LEU A 1 912  ? 165.125 185.291 138.860 1.00 4.92   ? 912  LEU A CD2 1 
ATOM 5824 N N   . ALA A 1 913  ? 165.861 188.571 134.496 1.00 14.42  ? 913  ALA A N   1 
ATOM 5825 C CA  . ALA A 1 913  ? 165.368 189.419 133.419 1.00 15.17  ? 913  ALA A CA  1 
ATOM 5826 C C   . ALA A 1 913  ? 164.909 188.580 132.233 1.00 20.08  ? 913  ALA A C   1 
ATOM 5827 O O   . ALA A 1 913  ? 163.844 188.834 131.658 1.00 24.37  ? 913  ALA A O   1 
ATOM 5828 C CB  . ALA A 1 913  ? 166.450 190.410 132.992 1.00 13.58  ? 913  ALA A CB  1 
ATOM 5829 N N   . GLU A 1 914  ? 165.693 187.563 131.864 1.00 17.56  ? 914  GLU A N   1 
ATOM 5830 C CA  . GLU A 1 914  ? 165.311 186.708 130.742 1.00 13.84  ? 914  GLU A CA  1 
ATOM 5831 C C   . GLU A 1 914  ? 164.014 185.952 131.024 1.00 18.91  ? 914  GLU A C   1 
ATOM 5832 O O   . GLU A 1 914  ? 163.130 185.879 130.162 1.00 31.00  ? 914  GLU A O   1 
ATOM 5833 C CB  . GLU A 1 914  ? 166.445 185.735 130.417 1.00 18.15  ? 914  GLU A CB  1 
ATOM 5834 C CG  . GLU A 1 914  ? 167.660 186.398 129.787 1.00 22.08  ? 914  GLU A CG  1 
ATOM 5835 C CD  . GLU A 1 914  ? 168.886 185.506 129.792 1.00 24.64  ? 914  GLU A CD  1 
ATOM 5836 O OE1 . GLU A 1 914  ? 168.804 184.381 130.327 1.00 28.55  ? 914  GLU A OE1 1 
ATOM 5837 O OE2 . GLU A 1 914  ? 169.933 185.931 129.259 1.00 22.59  ? 914  GLU A OE2 1 
ATOM 5838 N N   . ILE A 1 915  ? 163.883 185.386 132.225 1.00 18.51  ? 915  ILE A N   1 
ATOM 5839 C CA  . ILE A 1 915  ? 162.681 184.634 132.583 1.00 15.92  ? 915  ILE A CA  1 
ATOM 5840 C C   . ILE A 1 915  ? 161.467 185.550 132.605 1.00 21.65  ? 915  ILE A C   1 
ATOM 5841 O O   . ILE A 1 915  ? 160.379 185.176 132.151 1.00 33.04  ? 915  ILE A O   1 
ATOM 5842 C CB  . ILE A 1 915  ? 162.872 183.920 133.934 1.00 14.65  ? 915  ILE A CB  1 
ATOM 5843 C CG1 . ILE A 1 915  ? 164.127 183.049 133.916 1.00 12.19  ? 915  ILE A CG1 1 
ATOM 5844 C CG2 . ILE A 1 915  ? 161.651 183.081 134.275 1.00 18.12  ? 915  ILE A CG2 1 
ATOM 5845 C CD1 . ILE A 1 915  ? 164.351 182.279 135.190 1.00 13.76  ? 915  ILE A CD1 1 
ATOM 5846 N N   . LYS A 1 916  ? 161.629 186.761 133.142 1.00 16.57  ? 916  LYS A N   1 
ATOM 5847 C CA  . LYS A 1 916  ? 160.529 187.716 133.168 1.00 17.31  ? 916  LYS A CA  1 
ATOM 5848 C C   . LYS A 1 916  ? 160.116 188.121 131.759 1.00 23.87  ? 916  LYS A C   1 
ATOM 5849 O O   . LYS A 1 916  ? 158.923 188.264 131.472 1.00 29.13  ? 916  LYS A O   1 
ATOM 5850 C CB  . LYS A 1 916  ? 160.936 188.942 133.987 1.00 23.97  ? 916  LYS A CB  1 
ATOM 5851 C CG  . LYS A 1 916  ? 159.912 190.058 134.022 1.00 22.48  ? 916  LYS A CG  1 
ATOM 5852 C CD  . LYS A 1 916  ? 160.560 191.364 134.451 1.00 21.67  ? 916  LYS A CD  1 
ATOM 5853 C CE  . LYS A 1 916  ? 159.732 192.081 135.502 1.00 22.70  ? 916  LYS A CE  1 
ATOM 5854 N NZ  . LYS A 1 916  ? 160.191 193.483 135.698 1.00 22.21  ? 916  LYS A NZ  1 
ATOM 5855 N N   . HIS A 1 917  ? 161.088 188.309 130.864 1.00 25.63  ? 917  HIS A N   1 
ATOM 5856 C CA  . HIS A 1 917  ? 160.768 188.793 129.527 1.00 28.44  ? 917  HIS A CA  1 
ATOM 5857 C C   . HIS A 1 917  ? 160.183 187.711 128.626 1.00 30.38  ? 917  HIS A C   1 
ATOM 5858 O O   . HIS A 1 917  ? 159.269 187.998 127.845 1.00 35.16  ? 917  HIS A O   1 
ATOM 5859 C CB  . HIS A 1 917  ? 162.013 189.401 128.880 1.00 26.99  ? 917  HIS A CB  1 
ATOM 5860 C CG  . HIS A 1 917  ? 162.520 190.623 129.581 1.00 32.47  ? 917  HIS A CG  1 
ATOM 5861 N ND1 . HIS A 1 917  ? 161.842 191.217 130.624 1.00 32.24  ? 917  HIS A ND1 1 
ATOM 5862 C CD2 . HIS A 1 917  ? 163.636 191.364 129.388 1.00 32.50  ? 917  HIS A CD2 1 
ATOM 5863 C CE1 . HIS A 1 917  ? 162.520 192.270 131.044 1.00 31.01  ? 917  HIS A CE1 1 
ATOM 5864 N NE2 . HIS A 1 917  ? 163.612 192.382 130.311 1.00 36.26  ? 917  HIS A NE2 1 
ATOM 5865 N N   . THR A 1 918  ? 160.675 186.475 128.709 1.00 25.87  ? 918  THR A N   1 
ATOM 5866 C CA  . THR A 1 918  ? 160.250 185.451 127.756 1.00 32.15  ? 918  THR A CA  1 
ATOM 5867 C C   . THR A 1 918  ? 159.044 184.654 128.247 1.00 30.41  ? 918  THR A C   1 
ATOM 5868 O O   . THR A 1 918  ? 158.001 184.628 127.587 1.00 36.05  ? 918  THR A O   1 
ATOM 5869 C CB  . THR A 1 918  ? 161.410 184.499 127.432 1.00 29.92  ? 918  THR A CB  1 
ATOM 5870 O OG1 . THR A 1 918  ? 161.839 183.831 128.625 1.00 33.32  ? 918  THR A OG1 1 
ATOM 5871 C CG2 . THR A 1 918  ? 162.576 185.253 126.808 1.00 29.45  ? 918  THR A CG2 1 
ATOM 5872 N N   . SER A 1 919  ? 159.171 183.996 129.399 1.00 24.76  ? 919  SER A N   1 
ATOM 5873 C CA  . SER A 1 919  ? 158.184 183.012 129.818 1.00 30.35  ? 919  SER A CA  1 
ATOM 5874 C C   . SER A 1 919  ? 157.365 183.410 131.037 1.00 31.63  ? 919  SER A C   1 
ATOM 5875 O O   . SER A 1 919  ? 156.287 182.841 131.240 1.00 28.79  ? 919  SER A O   1 
ATOM 5876 C CB  . SER A 1 919  ? 158.871 181.668 130.102 1.00 30.65  ? 919  SER A CB  1 
ATOM 5877 O OG  . SER A 1 919  ? 159.741 181.773 131.214 1.00 28.25  ? 919  SER A OG  1 
ATOM 5878 N N   . LYS A 1 920  ? 157.839 184.359 131.847 1.00 28.65  ? 920  LYS A N   1 
ATOM 5879 C CA  . LYS A 1 920  ? 157.127 184.823 133.041 1.00 26.91  ? 920  LYS A CA  1 
ATOM 5880 C C   . LYS A 1 920  ? 156.792 183.659 133.979 1.00 27.18  ? 920  LYS A C   1 
ATOM 5881 O O   . LYS A 1 920  ? 155.637 183.428 134.342 1.00 25.27  ? 920  LYS A O   1 
ATOM 5882 C CB  . LYS A 1 920  ? 155.858 185.595 132.661 1.00 27.05  ? 920  LYS A CB  1 
ATOM 5883 C CG  . LYS A 1 920  ? 156.092 187.026 132.219 1.00 26.83  ? 920  LYS A CG  1 
ATOM 5884 C CD  . LYS A 1 920  ? 154.951 187.935 132.653 1.00 27.79  ? 920  LYS A CD  1 
ATOM 5885 C CE  . LYS A 1 920  ? 154.856 188.029 134.157 1.00 30.00  ? 920  LYS A CE  1 
ATOM 5886 N NZ  . LYS A 1 920  ? 155.952 188.842 134.742 1.00 28.04  ? 920  LYS A NZ  1 
ATOM 5887 N N   . ASP A 1 921  ? 157.828 182.924 134.368 1.00 25.60  ? 921  ASP A N   1 
ATOM 5888 C CA  . ASP A 1 921  ? 157.681 181.833 135.320 1.00 24.43  ? 921  ASP A CA  1 
ATOM 5889 C C   . ASP A 1 921  ? 158.046 182.297 136.724 1.00 23.65  ? 921  ASP A C   1 
ATOM 5890 O O   . ASP A 1 921  ? 158.543 183.404 136.939 1.00 25.29  ? 921  ASP A O   1 
ATOM 5891 C CB  . ASP A 1 921  ? 158.547 180.634 134.926 1.00 25.65  ? 921  ASP A CB  1 
ATOM 5892 C CG  . ASP A 1 921  ? 158.058 179.949 133.672 1.00 29.73  ? 921  ASP A CG  1 
ATOM 5893 O OD1 . ASP A 1 921  ? 156.839 179.991 133.409 1.00 33.50  ? 921  ASP A OD1 1 
ATOM 5894 O OD2 . ASP A 1 921  ? 158.891 179.355 132.957 1.00 28.81  ? 921  ASP A OD2 1 
ATOM 5895 N N   . LYS A 1 922  ? 157.791 181.420 137.688 1.00 19.90  ? 922  LYS A N   1 
ATOM 5896 C CA  . LYS A 1 922  ? 158.143 181.660 139.077 1.00 19.72  ? 922  LYS A CA  1 
ATOM 5897 C C   . LYS A 1 922  ? 159.463 180.971 139.392 1.00 20.13  ? 922  LYS A C   1 
ATOM 5898 O O   . LYS A 1 922  ? 159.747 179.882 138.884 1.00 20.99  ? 922  LYS A O   1 
ATOM 5899 C CB  . LYS A 1 922  ? 157.042 181.166 140.011 1.00 20.51  ? 922  LYS A CB  1 
ATOM 5900 C CG  . LYS A 1 922  ? 155.750 181.935 139.878 1.00 24.47  ? 922  LYS A CG  1 
ATOM 5901 C CD  . LYS A 1 922  ? 154.702 181.413 140.832 1.00 25.49  ? 922  LYS A CD  1 
ATOM 5902 C CE  . LYS A 1 922  ? 153.451 182.254 140.744 1.00 25.56  ? 922  LYS A CE  1 
ATOM 5903 N NZ  . LYS A 1 922  ? 152.794 182.105 139.418 1.00 27.28  ? 922  LYS A NZ  1 
ATOM 5904 N N   . VAL A 1 923  ? 160.269 181.615 140.229 1.00 13.83  ? 923  VAL A N   1 
ATOM 5905 C CA  . VAL A 1 923  ? 161.654 181.229 140.451 1.00 3.85   ? 923  VAL A CA  1 
ATOM 5906 C C   . VAL A 1 923  ? 161.877 180.981 141.935 1.00 7.45   ? 923  VAL A C   1 
ATOM 5907 O O   . VAL A 1 923  ? 161.402 181.745 142.782 1.00 21.35  ? 923  VAL A O   1 
ATOM 5908 C CB  . VAL A 1 923  ? 162.618 182.313 139.926 1.00 5.44   ? 923  VAL A CB  1 
ATOM 5909 C CG1 . VAL A 1 923  ? 163.968 182.189 140.586 1.00 7.51   ? 923  VAL A CG1 1 
ATOM 5910 C CG2 . VAL A 1 923  ? 162.748 182.221 138.418 1.00 9.71   ? 923  VAL A CG2 1 
ATOM 5911 N N   . ILE A 1 924  ? 162.592 179.903 142.247 1.00 1.93   ? 924  ILE A N   1 
ATOM 5912 C CA  . ILE A 1 924  ? 163.032 179.599 143.604 1.00 1.86   ? 924  ILE A CA  1 
ATOM 5913 C C   . ILE A 1 924  ? 164.542 179.764 143.664 1.00 5.29   ? 924  ILE A C   1 
ATOM 5914 O O   . ILE A 1 924  ? 165.269 179.161 142.865 1.00 15.54  ? 924  ILE A O   1 
ATOM 5915 C CB  . ILE A 1 924  ? 162.637 178.174 144.023 1.00 2.89   ? 924  ILE A CB  1 
ATOM 5916 C CG1 . ILE A 1 924  ? 161.127 177.973 143.935 1.00 10.09  ? 924  ILE A CG1 1 
ATOM 5917 C CG2 . ILE A 1 924  ? 163.132 177.890 145.426 1.00 5.14   ? 924  ILE A CG2 1 
ATOM 5918 C CD1 . ILE A 1 924  ? 160.747 176.532 143.927 1.00 9.73   ? 924  ILE A CD1 1 
ATOM 5919 N N   . ILE A 1 925  ? 165.015 180.573 144.606 1.00 1.48   ? 925  ILE A N   1 
ATOM 5920 C CA  . ILE A 1 925  ? 166.432 180.643 144.940 1.00 0.00   ? 925  ILE A CA  1 
ATOM 5921 C C   . ILE A 1 925  ? 166.622 179.964 146.287 1.00 0.00   ? 925  ILE A C   1 
ATOM 5922 O O   . ILE A 1 925  ? 165.980 180.338 147.275 1.00 2.12   ? 925  ILE A O   1 
ATOM 5923 C CB  . ILE A 1 925  ? 166.957 182.086 144.973 1.00 1.79   ? 925  ILE A CB  1 
ATOM 5924 C CG1 . ILE A 1 925  ? 166.389 182.902 143.815 1.00 4.86   ? 925  ILE A CG1 1 
ATOM 5925 C CG2 . ILE A 1 925  ? 168.477 182.099 144.942 1.00 6.43   ? 925  ILE A CG2 1 
ATOM 5926 C CD1 . ILE A 1 925  ? 166.689 184.374 143.931 1.00 3.47   ? 925  ILE A CD1 1 
ATOM 5927 N N   . PHE A 1 926  ? 167.495 178.964 146.323 1.00 4.10   ? 926  PHE A N   1 
ATOM 5928 C CA  . PHE A 1 926  ? 167.814 178.248 147.548 1.00 0.00   ? 926  PHE A CA  1 
ATOM 5929 C C   . PHE A 1 926  ? 169.139 178.754 148.098 1.00 4.52   ? 926  PHE A C   1 
ATOM 5930 O O   . PHE A 1 926  ? 170.158 178.735 147.400 1.00 9.54   ? 926  PHE A O   1 
ATOM 5931 C CB  . PHE A 1 926  ? 167.874 176.740 147.311 1.00 1.04   ? 926  PHE A CB  1 
ATOM 5932 C CG  . PHE A 1 926  ? 166.530 176.079 147.289 1.00 4.58   ? 926  PHE A CG  1 
ATOM 5933 C CD1 . PHE A 1 926  ? 166.019 175.552 146.117 1.00 4.36   ? 926  PHE A CD1 1 
ATOM 5934 C CD2 . PHE A 1 926  ? 165.774 175.988 148.443 1.00 1.94   ? 926  PHE A CD2 1 
ATOM 5935 C CE1 . PHE A 1 926  ? 164.783 174.942 146.102 1.00 3.40   ? 926  PHE A CE1 1 
ATOM 5936 C CE2 . PHE A 1 926  ? 164.538 175.382 148.432 1.00 2.97   ? 926  PHE A CE2 1 
ATOM 5937 C CZ  . PHE A 1 926  ? 164.041 174.860 147.261 1.00 3.95   ? 926  PHE A CZ  1 
ATOM 5938 N N   . THR A 1 927  ? 169.111 179.216 149.343 1.00 4.49   ? 927  THR A N   1 
ATOM 5939 C CA  . THR A 1 927  ? 170.306 179.612 150.070 1.00 4.04   ? 927  THR A CA  1 
ATOM 5940 C C   . THR A 1 927  ? 169.954 179.639 151.549 1.00 7.02   ? 927  THR A C   1 
ATOM 5941 O O   . THR A 1 927  ? 168.820 179.958 151.915 1.00 14.34  ? 927  THR A O   1 
ATOM 5942 C CB  . THR A 1 927  ? 170.840 180.973 149.601 1.00 4.95   ? 927  THR A CB  1 
ATOM 5943 O OG1 . THR A 1 927  ? 172.003 181.319 150.362 1.00 4.18   ? 927  THR A OG1 1 
ATOM 5944 C CG2 . THR A 1 927  ? 169.790 182.058 149.753 1.00 3.27   ? 927  THR A CG2 1 
ATOM 5945 N N   . GLU A 1 928  ? 170.917 179.272 152.387 1.00 6.02   ? 928  GLU A N   1 
ATOM 5946 C CA  . GLU A 1 928  ? 170.701 179.165 153.822 1.00 1.24   ? 928  GLU A CA  1 
ATOM 5947 C C   . GLU A 1 928  ? 171.296 180.327 154.603 1.00 6.97   ? 928  GLU A C   1 
ATOM 5948 O O   . GLU A 1 928  ? 171.171 180.359 155.830 1.00 12.20  ? 928  GLU A O   1 
ATOM 5949 C CB  . GLU A 1 928  ? 171.280 177.845 154.339 1.00 10.38  ? 928  GLU A CB  1 
ATOM 5950 C CG  . GLU A 1 928  ? 172.799 177.777 154.301 1.00 18.22  ? 928  GLU A CG  1 
ATOM 5951 C CD  . GLU A 1 928  ? 173.342 177.341 152.950 1.00 22.82  ? 928  GLU A CD  1 
ATOM 5952 O OE1 . GLU A 1 928  ? 172.588 177.374 151.954 1.00 20.50  ? 928  GLU A OE1 1 
ATOM 5953 O OE2 . GLU A 1 928  ? 174.528 176.960 152.886 1.00 22.67  ? 928  GLU A OE2 1 
ATOM 5954 N N   . LEU A 1 929  ? 171.930 181.280 153.928 1.00 7.44   ? 929  LEU A N   1 
ATOM 5955 C CA  . LEU A 1 929  ? 172.590 182.395 154.592 1.00 1.51   ? 929  LEU A CA  1 
ATOM 5956 C C   . LEU A 1 929  ? 171.619 183.564 154.686 1.00 0.30   ? 929  LEU A C   1 
ATOM 5957 O O   . LEU A 1 929  ? 171.118 184.039 153.665 1.00 10.68  ? 929  LEU A O   1 
ATOM 5958 C CB  . LEU A 1 929  ? 173.853 182.790 153.828 1.00 0.12   ? 929  LEU A CB  1 
ATOM 5959 C CG  . LEU A 1 929  ? 174.738 181.615 153.402 1.00 8.19   ? 929  LEU A CG  1 
ATOM 5960 C CD1 . LEU A 1 929  ? 175.649 182.015 152.255 1.00 8.72   ? 929  LEU A CD1 1 
ATOM 5961 C CD2 . LEU A 1 929  ? 175.548 181.087 154.574 1.00 6.11   ? 929  LEU A CD2 1 
ATOM 5962 N N   . ARG A 1 930  ? 171.354 184.022 155.912 1.00 2.28   ? 930  ARG A N   1 
ATOM 5963 C CA  . ARG A 1 930  ? 170.376 185.088 156.119 1.00 1.57   ? 930  ARG A CA  1 
ATOM 5964 C C   . ARG A 1 930  ? 170.813 186.377 155.436 1.00 0.00   ? 930  ARG A C   1 
ATOM 5965 O O   . ARG A 1 930  ? 170.015 187.047 154.769 1.00 4.53   ? 930  ARG A O   1 
ATOM 5966 C CB  . ARG A 1 930  ? 170.175 185.326 157.616 1.00 7.88   ? 930  ARG A CB  1 
ATOM 5967 C CG  . ARG A 1 930  ? 169.814 184.089 158.415 1.00 2.90   ? 930  ARG A CG  1 
ATOM 5968 C CD  . ARG A 1 930  ? 168.533 183.449 157.923 1.00 6.74   ? 930  ARG A CD  1 
ATOM 5969 N NE  . ARG A 1 930  ? 168.057 182.434 158.854 1.00 5.44   ? 930  ARG A NE  1 
ATOM 5970 C CZ  . ARG A 1 930  ? 168.512 181.190 158.905 1.00 6.09   ? 930  ARG A CZ  1 
ATOM 5971 N NH1 . ARG A 1 930  ? 169.458 180.766 158.084 1.00 11.50  ? 930  ARG A NH1 1 
ATOM 5972 N NH2 . ARG A 1 930  ? 168.006 180.350 159.802 1.00 6.54   ? 930  ARG A NH2 1 
ATOM 5973 N N   . ASP A 1 931  ? 172.086 186.739 155.597 1.00 0.00   ? 931  ASP A N   1 
ATOM 5974 C CA  . ASP A 1 931  ? 172.600 187.963 154.996 1.00 0.00   ? 931  ASP A CA  1 
ATOM 5975 C C   . ASP A 1 931  ? 172.584 187.888 153.472 1.00 3.63   ? 931  ASP A C   1 
ATOM 5976 O O   . ASP A 1 931  ? 172.235 188.866 152.799 1.00 4.28   ? 931  ASP A O   1 
ATOM 5977 C CB  . ASP A 1 931  ? 174.001 188.243 155.542 1.00 1.27   ? 931  ASP A CB  1 
ATOM 5978 C CG  . ASP A 1 931  ? 175.002 187.156 155.190 1.00 16.88  ? 931  ASP A CG  1 
ATOM 5979 O OD1 . ASP A 1 931  ? 174.618 186.155 154.551 1.00 18.65  ? 931  ASP A OD1 1 
ATOM 5980 O OD2 . ASP A 1 931  ? 176.174 187.285 155.593 1.00 16.78  ? 931  ASP A OD2 1 
ATOM 5981 N N   . LEU A 1 932  ? 172.949 186.732 152.909 1.00 5.53   ? 932  LEU A N   1 
ATOM 5982 C CA  . LEU A 1 932  ? 172.837 186.549 151.465 1.00 0.00   ? 932  LEU A CA  1 
ATOM 5983 C C   . LEU A 1 932  ? 171.387 186.618 151.012 1.00 0.00   ? 932  LEU A C   1 
ATOM 5984 O O   . LEU A 1 932  ? 171.090 187.155 149.940 1.00 9.04   ? 932  LEU A O   1 
ATOM 5985 C CB  . LEU A 1 932  ? 173.464 185.222 151.047 1.00 4.97   ? 932  LEU A CB  1 
ATOM 5986 C CG  . LEU A 1 932  ? 173.542 185.020 149.533 1.00 2.12   ? 932  LEU A CG  1 
ATOM 5987 C CD1 . LEU A 1 932  ? 174.558 185.953 148.928 1.00 2.92   ? 932  LEU A CD1 1 
ATOM 5988 C CD2 . LEU A 1 932  ? 173.886 183.588 149.200 1.00 4.18   ? 932  LEU A CD2 1 
ATOM 5989 N N   . GLN A 1 933  ? 170.471 186.069 151.812 1.00 0.00   ? 933  GLN A N   1 
ATOM 5990 C CA  . GLN A 1 933  ? 169.052 186.181 151.497 1.00 0.00   ? 933  GLN A CA  1 
ATOM 5991 C C   . GLN A 1 933  ? 168.619 187.638 151.424 1.00 4.59   ? 933  GLN A C   1 
ATOM 5992 O O   . GLN A 1 933  ? 167.912 188.038 150.492 1.00 9.37   ? 933  GLN A O   1 
ATOM 5993 C CB  . GLN A 1 933  ? 168.232 185.428 152.542 1.00 0.00   ? 933  GLN A CB  1 
ATOM 5994 C CG  . GLN A 1 933  ? 168.438 183.932 152.513 1.00 0.00   ? 933  GLN A CG  1 
ATOM 5995 C CD  . GLN A 1 933  ? 167.642 183.215 153.571 1.00 4.46   ? 933  GLN A CD  1 
ATOM 5996 O OE1 . GLN A 1 933  ? 166.975 183.841 154.387 1.00 12.92  ? 933  GLN A OE1 1 
ATOM 5997 N NE2 . GLN A 1 933  ? 167.696 181.891 153.558 1.00 3.88   ? 933  GLN A NE2 1 
ATOM 5998 N N   . ARG A 1 934  ? 169.047 188.452 152.392 1.00 3.37   ? 934  ARG A N   1 
ATOM 5999 C CA  . ARG A 1 934  ? 168.691 189.867 152.374 1.00 0.00   ? 934  ARG A CA  1 
ATOM 6000 C C   . ARG A 1 934  ? 169.306 190.584 151.178 1.00 2.10   ? 934  ARG A C   1 
ATOM 6001 O O   . ARG A 1 934  ? 168.653 191.429 150.554 1.00 10.10  ? 934  ARG A O   1 
ATOM 6002 C CB  . ARG A 1 934  ? 169.122 190.541 153.674 1.00 0.00   ? 934  ARG A CB  1 
ATOM 6003 C CG  . ARG A 1 934  ? 168.352 190.097 154.899 1.00 0.00   ? 934  ARG A CG  1 
ATOM 6004 C CD  . ARG A 1 934  ? 168.702 190.962 156.093 1.00 0.00   ? 934  ARG A CD  1 
ATOM 6005 N NE  . ARG A 1 934  ? 170.101 190.835 156.483 1.00 0.00   ? 934  ARG A NE  1 
ATOM 6006 C CZ  . ARG A 1 934  ? 170.563 189.925 157.328 1.00 0.00   ? 934  ARG A CZ  1 
ATOM 6007 N NH1 . ARG A 1 934  ? 169.766 189.029 157.884 1.00 0.00   ? 934  ARG A NH1 1 
ATOM 6008 N NH2 . ARG A 1 934  ? 171.859 189.916 157.625 1.00 0.00   ? 934  ARG A NH2 1 
ATOM 6009 N N   . GLU A 1 935  ? 170.565 190.276 150.853 1.00 0.00   ? 935  GLU A N   1 
ATOM 6010 C CA  . GLU A 1 935  ? 171.208 190.921 149.710 1.00 0.00   ? 935  GLU A CA  1 
ATOM 6011 C C   . GLU A 1 935  ? 170.504 190.568 148.405 1.00 4.03   ? 935  GLU A C   1 
ATOM 6012 O O   . GLU A 1 935  ? 170.269 191.442 147.560 1.00 5.87   ? 935  GLU A O   1 
ATOM 6013 C CB  . GLU A 1 935  ? 172.684 190.528 149.642 1.00 2.26   ? 935  GLU A CB  1 
ATOM 6014 C CG  . GLU A 1 935  ? 173.504 190.952 150.849 1.00 10.99  ? 935  GLU A CG  1 
ATOM 6015 C CD  . GLU A 1 935  ? 173.840 192.429 150.845 1.00 15.99  ? 935  GLU A CD  1 
ATOM 6016 O OE1 . GLU A 1 935  ? 174.104 192.979 149.756 1.00 14.50  ? 935  GLU A OE1 1 
ATOM 6017 O OE2 . GLU A 1 935  ? 173.841 193.041 151.933 1.00 7.34   ? 935  GLU A OE2 1 
ATOM 6018 N N   . LEU A 1 936  ? 170.155 189.292 148.225 1.00 5.25   ? 936  LEU A N   1 
ATOM 6019 C CA  . LEU A 1 936  ? 169.435 188.879 147.026 1.00 0.00   ? 936  LEU A CA  1 
ATOM 6020 C C   . LEU A 1 936  ? 168.057 189.522 146.963 1.00 0.00   ? 936  LEU A C   1 
ATOM 6021 O O   . LEU A 1 936  ? 167.604 189.930 145.888 1.00 5.31   ? 936  LEU A O   1 
ATOM 6022 C CB  . LEU A 1 936  ? 169.318 187.356 146.981 1.00 0.00   ? 936  LEU A CB  1 
ATOM 6023 C CG  . LEU A 1 936  ? 170.606 186.567 146.733 1.00 0.00   ? 936  LEU A CG  1 
ATOM 6024 C CD1 . LEU A 1 936  ? 170.292 185.110 146.446 1.00 0.00   ? 936  LEU A CD1 1 
ATOM 6025 C CD2 . LEU A 1 936  ? 171.418 187.178 145.602 1.00 0.00   ? 936  LEU A CD2 1 
ATOM 6026 N N   . GLN A 1 937  ? 167.373 189.615 148.107 1.00 1.44   ? 937  GLN A N   1 
ATOM 6027 C CA  . GLN A 1 937  ? 166.068 190.264 148.145 1.00 3.04   ? 937  GLN A CA  1 
ATOM 6028 C C   . GLN A 1 937  ? 166.169 191.730 147.746 1.00 3.63   ? 937  GLN A C   1 
ATOM 6029 O O   . GLN A 1 937  ? 165.350 192.227 146.964 1.00 6.19   ? 937  GLN A O   1 
ATOM 6030 C CB  . GLN A 1 937  ? 165.471 190.121 149.544 1.00 0.58   ? 937  GLN A CB  1 
ATOM 6031 C CG  . GLN A 1 937  ? 164.011 190.495 149.651 1.00 0.00   ? 937  GLN A CG  1 
ATOM 6032 C CD  . GLN A 1 937  ? 163.570 190.678 151.084 1.00 2.90   ? 937  GLN A CD  1 
ATOM 6033 O OE1 . GLN A 1 937  ? 164.135 191.483 151.820 1.00 9.36   ? 937  GLN A OE1 1 
ATOM 6034 N NE2 . GLN A 1 937  ? 162.557 189.925 151.490 1.00 3.00   ? 937  GLN A NE2 1 
ATOM 6035 N N   . HIS A 1 938  ? 167.178 192.435 148.263 1.00 0.36   ? 938  HIS A N   1 
ATOM 6036 C CA  . HIS A 1 938  ? 167.363 193.836 147.903 1.00 0.00   ? 938  HIS A CA  1 
ATOM 6037 C C   . HIS A 1 938  ? 167.682 193.990 146.421 1.00 6.72   ? 938  HIS A C   1 
ATOM 6038 O O   . HIS A 1 938  ? 167.173 194.903 145.762 1.00 11.68  ? 938  HIS A O   1 
ATOM 6039 C CB  . HIS A 1 938  ? 168.467 194.457 148.756 1.00 2.62   ? 938  HIS A CB  1 
ATOM 6040 C CG  . HIS A 1 938  ? 168.638 195.929 148.544 1.00 2.12   ? 938  HIS A CG  1 
ATOM 6041 N ND1 . HIS A 1 938  ? 167.638 196.839 148.807 1.00 4.34   ? 938  HIS A ND1 1 
ATOM 6042 C CD2 . HIS A 1 938  ? 169.693 196.648 148.094 1.00 1.62   ? 938  HIS A CD2 1 
ATOM 6043 C CE1 . HIS A 1 938  ? 168.070 198.056 148.528 1.00 6.53   ? 938  HIS A CE1 1 
ATOM 6044 N NE2 . HIS A 1 938  ? 169.314 197.968 148.094 1.00 5.18   ? 938  HIS A NE2 1 
ATOM 6045 N N   . ALA A 1 939  ? 168.528 193.110 145.879 1.00 6.51   ? 939  ALA A N   1 
ATOM 6046 C CA  . ALA A 1 939  ? 168.859 193.192 144.459 1.00 0.32   ? 939  ALA A CA  1 
ATOM 6047 C C   . ALA A 1 939  ? 167.633 192.949 143.586 1.00 4.26   ? 939  ALA A C   1 
ATOM 6048 O O   . ALA A 1 939  ? 167.402 193.671 142.604 1.00 6.79   ? 939  ALA A O   1 
ATOM 6049 C CB  . ALA A 1 939  ? 169.967 192.197 144.120 1.00 0.08   ? 939  ALA A CB  1 
ATOM 6050 N N   . ILE A 1 940  ? 166.837 191.931 143.922 1.00 7.59   ? 940  ILE A N   1 
ATOM 6051 C CA  . ILE A 1 940  ? 165.648 191.637 143.132 1.00 5.14   ? 940  ILE A CA  1 
ATOM 6052 C C   . ILE A 1 940  ? 164.647 192.779 143.234 1.00 15.82  ? 940  ILE A C   1 
ATOM 6053 O O   . ILE A 1 940  ? 163.986 193.132 142.250 1.00 19.11  ? 940  ILE A O   1 
ATOM 6054 C CB  . ILE A 1 940  ? 165.035 190.294 143.566 1.00 1.46   ? 940  ILE A CB  1 
ATOM 6055 C CG1 . ILE A 1 940  ? 165.931 189.143 143.117 1.00 10.30  ? 940  ILE A CG1 1 
ATOM 6056 C CG2 . ILE A 1 940  ? 163.642 190.121 142.982 1.00 1.71   ? 940  ILE A CG2 1 
ATOM 6057 C CD1 . ILE A 1 940  ? 165.760 187.891 143.930 1.00 6.77   ? 940  ILE A CD1 1 
ATOM 6058 N N   . HIS A 1 941  ? 164.528 193.388 144.416 1.00 12.60  ? 941  HIS A N   1 
ATOM 6059 C CA  . HIS A 1 941  ? 163.656 194.547 144.563 1.00 2.82   ? 941  HIS A CA  1 
ATOM 6060 C C   . HIS A 1 941  ? 164.132 195.709 143.700 1.00 8.08   ? 941  HIS A C   1 
ATOM 6061 O O   . HIS A 1 941  ? 163.328 196.376 143.040 1.00 18.66  ? 941  HIS A O   1 
ATOM 6062 C CB  . HIS A 1 941  ? 163.580 194.960 146.033 1.00 7.10   ? 941  HIS A CB  1 
ATOM 6063 C CG  . HIS A 1 941  ? 162.857 196.251 146.262 1.00 15.04  ? 941  HIS A CG  1 
ATOM 6064 N ND1 . HIS A 1 941  ? 161.485 196.325 146.372 1.00 13.00  ? 941  HIS A ND1 1 
ATOM 6065 C CD2 . HIS A 1 941  ? 163.315 197.517 146.407 1.00 10.23  ? 941  HIS A CD2 1 
ATOM 6066 C CE1 . HIS A 1 941  ? 161.129 197.581 146.571 1.00 12.32  ? 941  HIS A CE1 1 
ATOM 6067 N NE2 . HIS A 1 941  ? 162.220 198.324 146.596 1.00 12.60  ? 941  HIS A NE2 1 
ATOM 6068 N N   . GLN A 1 942  ? 165.443 195.966 143.690 1.00 6.67   ? 942  GLN A N   1 
ATOM 6069 C CA  . GLN A 1 942  ? 165.964 197.094 142.924 1.00 7.24   ? 942  GLN A CA  1 
ATOM 6070 C C   . GLN A 1 942  ? 165.751 196.904 141.428 1.00 14.20  ? 942  GLN A C   1 
ATOM 6071 O O   . GLN A 1 942  ? 165.297 197.825 140.740 1.00 12.52  ? 942  GLN A O   1 
ATOM 6072 C CB  . GLN A 1 942  ? 167.448 197.303 143.222 1.00 6.38   ? 942  GLN A CB  1 
ATOM 6073 C CG  . GLN A 1 942  ? 167.739 198.003 144.535 1.00 10.99  ? 942  GLN A CG  1 
ATOM 6074 C CD  . GLN A 1 942  ? 169.224 198.179 144.775 1.00 18.44  ? 942  GLN A CD  1 
ATOM 6075 O OE1 . GLN A 1 942  ? 169.989 197.215 144.736 1.00 16.52  ? 942  GLN A OE1 1 
ATOM 6076 N NE2 . GLN A 1 942  ? 169.642 199.414 145.025 1.00 12.65  ? 942  GLN A NE2 1 
ATOM 6077 N N   . ASN A 1 943  ? 166.072 195.719 140.901 1.00 17.40  ? 943  ASN A N   1 
ATOM 6078 C CA  . ASN A 1 943  ? 165.994 195.527 139.455 1.00 12.51  ? 943  ASN A CA  1 
ATOM 6079 C C   . ASN A 1 943  ? 164.645 195.020 138.956 1.00 14.64  ? 943  ASN A C   1 
ATOM 6080 O O   . ASN A 1 943  ? 164.458 194.928 137.737 1.00 20.27  ? 943  ASN A O   1 
ATOM 6081 C CB  . ASN A 1 943  ? 167.090 194.572 138.963 1.00 5.24   ? 943  ASN A CB  1 
ATOM 6082 C CG  . ASN A 1 943  ? 168.487 195.121 139.175 1.00 9.80   ? 943  ASN A CG  1 
ATOM 6083 O OD1 . ASN A 1 943  ? 169.272 194.580 139.949 1.00 10.92  ? 943  ASN A OD1 1 
ATOM 6084 N ND2 . ASN A 1 943  ? 168.803 196.205 138.480 1.00 17.81  ? 943  ASN A ND2 1 
ATOM 6085 N N   . PHE A 1 944  ? 163.697 194.695 139.837 1.00 11.90  ? 944  PHE A N   1 
ATOM 6086 C CA  . PHE A 1 944  ? 162.401 194.208 139.383 1.00 10.09  ? 944  PHE A CA  1 
ATOM 6087 C C   . PHE A 1 944  ? 161.210 194.787 140.136 1.00 19.10  ? 944  PHE A C   1 
ATOM 6088 O O   . PHE A 1 944  ? 160.069 194.459 139.793 1.00 22.51  ? 944  PHE A O   1 
ATOM 6089 C CB  . PHE A 1 944  ? 162.354 192.674 139.452 1.00 6.88   ? 944  PHE A CB  1 
ATOM 6090 C CG  . PHE A 1 944  ? 163.473 192.008 138.707 1.00 6.70   ? 944  PHE A CG  1 
ATOM 6091 C CD1 . PHE A 1 944  ? 163.462 191.955 137.324 1.00 13.53  ? 944  PHE A CD1 1 
ATOM 6092 C CD2 . PHE A 1 944  ? 164.540 191.446 139.385 1.00 8.26   ? 944  PHE A CD2 1 
ATOM 6093 C CE1 . PHE A 1 944  ? 164.490 191.351 136.632 1.00 12.97  ? 944  PHE A CE1 1 
ATOM 6094 C CE2 . PHE A 1 944  ? 165.571 190.840 138.697 1.00 11.51  ? 944  PHE A CE2 1 
ATOM 6095 C CZ  . PHE A 1 944  ? 165.546 190.793 137.319 1.00 10.21  ? 944  PHE A CZ  1 
ATOM 6096 N N   . GLY A 1 945  ? 161.433 195.626 141.144 1.00 18.00  ? 945  GLY A N   1 
ATOM 6097 C CA  . GLY A 1 945  ? 160.359 196.367 141.769 1.00 16.57  ? 945  GLY A CA  1 
ATOM 6098 C C   . GLY A 1 945  ? 159.537 195.619 142.796 1.00 22.26  ? 945  GLY A C   1 
ATOM 6099 O O   . GLY A 1 945  ? 158.559 196.183 143.303 1.00 22.11  ? 945  GLY A O   1 
ATOM 6100 N N   . PHE A 1 946  ? 159.886 194.377 143.125 1.00 12.89  ? 946  PHE A N   1 
ATOM 6101 C CA  . PHE A 1 946  ? 159.161 193.631 144.142 1.00 15.18  ? 946  PHE A CA  1 
ATOM 6102 C C   . PHE A 1 946  ? 160.148 192.918 145.053 1.00 13.58  ? 946  PHE A C   1 
ATOM 6103 O O   . PHE A 1 946  ? 161.216 192.481 144.617 1.00 18.09  ? 946  PHE A O   1 
ATOM 6104 C CB  . PHE A 1 946  ? 158.183 192.621 143.522 1.00 14.33  ? 946  PHE A CB  1 
ATOM 6105 C CG  . PHE A 1 946  ? 158.848 191.412 142.928 1.00 13.76  ? 946  PHE A CG  1 
ATOM 6106 C CD1 . PHE A 1 946  ? 159.399 191.463 141.660 1.00 16.51  ? 946  PHE A CD1 1 
ATOM 6107 C CD2 . PHE A 1 946  ? 158.910 190.223 143.633 1.00 7.64   ? 946  PHE A CD2 1 
ATOM 6108 C CE1 . PHE A 1 946  ? 160.007 190.353 141.110 1.00 14.82  ? 946  PHE A CE1 1 
ATOM 6109 C CE2 . PHE A 1 946  ? 159.517 189.112 143.090 1.00 7.26   ? 946  PHE A CE2 1 
ATOM 6110 C CZ  . PHE A 1 946  ? 160.066 189.177 141.827 1.00 16.37  ? 946  PHE A CZ  1 
ATOM 6111 N N   . ARG A 1 947  ? 159.775 192.801 146.326 1.00 10.71  ? 947  ARG A N   1 
ATOM 6112 C CA  . ARG A 1 947  ? 160.620 192.148 147.317 1.00 6.33   ? 947  ARG A CA  1 
ATOM 6113 C C   . ARG A 1 947  ? 160.275 190.668 147.391 1.00 10.05  ? 947  ARG A C   1 
ATOM 6114 O O   . ARG A 1 947  ? 159.137 190.328 147.741 1.00 13.53  ? 947  ARG A O   1 
ATOM 6115 C CB  . ARG A 1 947  ? 160.439 192.787 148.684 1.00 5.24   ? 947  ARG A CB  1 
ATOM 6116 C CG  . ARG A 1 947  ? 160.903 194.228 148.761 1.00 12.15  ? 947  ARG A CG  1 
ATOM 6117 C CD  . ARG A 1 947  ? 160.676 194.825 150.142 1.00 13.61  ? 947  ARG A CD  1 
ATOM 6118 N NE  . ARG A 1 947  ? 161.502 194.201 151.170 1.00 13.97  ? 947  ARG A NE  1 
ATOM 6119 C CZ  . ARG A 1 947  ? 161.038 193.412 152.129 1.00 10.06  ? 947  ARG A CZ  1 
ATOM 6120 N NH1 . ARG A 1 947  ? 159.753 193.116 152.219 1.00 10.92  ? 947  ARG A NH1 1 
ATOM 6121 N NH2 . ARG A 1 947  ? 161.885 192.912 153.024 1.00 10.99  ? 947  ARG A NH2 1 
ATOM 6122 N N   . PRO A 1 948  ? 161.199 189.767 147.066 1.00 9.45   ? 948  PRO A N   1 
ATOM 6123 C CA  . PRO A 1 948  ? 160.924 188.337 147.240 1.00 2.03   ? 948  PRO A CA  1 
ATOM 6124 C C   . PRO A 1 948  ? 160.736 187.981 148.706 1.00 6.18   ? 948  PRO A C   1 
ATOM 6125 O O   . PRO A 1 948  ? 161.339 188.578 149.602 1.00 4.11   ? 948  PRO A O   1 
ATOM 6126 C CB  . PRO A 1 948  ? 162.163 187.647 146.657 1.00 0.00   ? 948  PRO A CB  1 
ATOM 6127 C CG  . PRO A 1 948  ? 163.164 188.704 146.416 1.00 6.61   ? 948  PRO A CG  1 
ATOM 6128 C CD  . PRO A 1 948  ? 162.503 190.034 146.437 1.00 7.50   ? 948  PRO A CD  1 
ATOM 6129 N N   . VAL A 1 949  ? 159.883 186.992 148.942 1.00 8.32   ? 949  VAL A N   1 
ATOM 6130 C CA  . VAL A 1 949  ? 159.592 186.533 150.295 1.00 1.77   ? 949  VAL A CA  1 
ATOM 6131 C C   . VAL A 1 949  ? 160.672 185.551 150.728 1.00 4.03   ? 949  VAL A C   1 
ATOM 6132 O O   . VAL A 1 949  ? 161.072 184.668 149.960 1.00 13.41  ? 949  VAL A O   1 
ATOM 6133 C CB  . VAL A 1 949  ? 158.195 185.895 150.362 1.00 6.29   ? 949  VAL A CB  1 
ATOM 6134 C CG1 . VAL A 1 949  ? 157.935 185.323 151.741 1.00 4.26   ? 949  VAL A CG1 1 
ATOM 6135 C CG2 . VAL A 1 949  ? 157.133 186.918 150.001 1.00 7.39   ? 949  VAL A CG2 1 
ATOM 6136 N N   . ILE A 1 950  ? 161.152 185.706 151.959 1.00 0.00   ? 950  ILE A N   1 
ATOM 6137 C CA  . ILE A 1 950  ? 162.204 184.867 152.519 1.00 0.00   ? 950  ILE A CA  1 
ATOM 6138 C C   . ILE A 1 950  ? 161.597 183.986 153.602 1.00 6.78   ? 950  ILE A C   1 
ATOM 6139 O O   . ILE A 1 950  ? 160.911 184.484 154.503 1.00 13.37  ? 950  ILE A O   1 
ATOM 6140 C CB  . ILE A 1 950  ? 163.355 185.715 153.084 1.00 0.00   ? 950  ILE A CB  1 
ATOM 6141 C CG1 . ILE A 1 950  ? 164.133 186.384 151.953 1.00 2.34   ? 950  ILE A CG1 1 
ATOM 6142 C CG2 . ILE A 1 950  ? 164.270 184.863 153.916 1.00 3.49   ? 950  ILE A CG2 1 
ATOM 6143 C CD1 . ILE A 1 950  ? 165.109 187.428 152.432 1.00 0.00   ? 950  ILE A CD1 1 
ATOM 6144 N N   . ILE A 1 951  ? 161.843 182.681 153.513 1.00 6.66   ? 951  ILE A N   1 
ATOM 6145 C CA  . ILE A 1 951  ? 161.349 181.710 154.483 1.00 9.48   ? 951  ILE A CA  1 
ATOM 6146 C C   . ILE A 1 951  ? 162.489 180.773 154.858 1.00 11.56  ? 951  ILE A C   1 
ATOM 6147 O O   . ILE A 1 951  ? 163.162 180.226 153.978 1.00 12.26  ? 951  ILE A O   1 
ATOM 6148 C CB  . ILE A 1 951  ? 160.146 180.923 153.932 1.00 10.48  ? 951  ILE A CB  1 
ATOM 6149 C CG1 . ILE A 1 951  ? 158.907 181.818 153.902 1.00 12.94  ? 951  ILE A CG1 1 
ATOM 6150 C CG2 . ILE A 1 951  ? 159.887 179.677 154.762 1.00 19.88  ? 951  ILE A CG2 1 
ATOM 6151 C CD1 . ILE A 1 951  ? 157.855 181.376 152.926 1.00 12.84  ? 951  ILE A CD1 1 
ATOM 6152 N N   . ASN A 1 952  ? 162.706 180.588 156.164 1.00 9.62   ? 952  ASN A N   1 
ATOM 6153 C CA  . ASN A 1 952  ? 163.795 179.757 156.661 1.00 12.70  ? 952  ASN A CA  1 
ATOM 6154 C C   . ASN A 1 952  ? 163.383 178.707 157.681 1.00 19.57  ? 952  ASN A C   1 
ATOM 6155 O O   . ASN A 1 952  ? 164.190 177.818 157.972 1.00 24.42  ? 952  ASN A O   1 
ATOM 6156 C CB  . ASN A 1 952  ? 164.889 180.621 157.306 1.00 10.69  ? 952  ASN A CB  1 
ATOM 6157 C CG  . ASN A 1 952  ? 165.446 181.657 156.367 1.00 11.60  ? 952  ASN A CG  1 
ATOM 6158 O OD1 . ASN A 1 952  ? 166.381 181.386 155.616 1.00 16.41  ? 952  ASN A OD1 1 
ATOM 6159 N ND2 . ASN A 1 952  ? 164.890 182.859 156.415 1.00 13.00  ? 952  ASN A ND2 1 
ATOM 6160 N N   . GLY A 1 953  ? 162.179 178.777 158.239 1.00 31.73  ? 953  GLY A N   1 
ATOM 6161 C CA  . GLY A 1 953  ? 161.881 177.981 159.413 1.00 39.06  ? 953  GLY A CA  1 
ATOM 6162 C C   . GLY A 1 953  ? 160.724 177.010 159.314 1.00 40.60  ? 953  GLY A C   1 
ATOM 6163 O O   . GLY A 1 953  ? 159.958 176.876 160.272 1.00 46.46  ? 953  GLY A O   1 
ATOM 6164 N N   . ASP A 1 954  ? 160.579 176.327 158.179 1.00 42.67  ? 954  ASP A N   1 
ATOM 6165 C CA  . ASP A 1 954  ? 159.543 175.308 158.054 1.00 45.75  ? 954  ASP A CA  1 
ATOM 6166 C C   . ASP A 1 954  ? 159.733 174.236 159.121 1.00 47.26  ? 954  ASP A C   1 
ATOM 6167 O O   . ASP A 1 954  ? 160.702 173.471 159.077 1.00 48.86  ? 954  ASP A O   1 
ATOM 6168 C CB  . ASP A 1 954  ? 159.561 174.684 156.657 1.00 50.86  ? 954  ASP A CB  1 
ATOM 6169 C CG  . ASP A 1 954  ? 158.904 175.567 155.615 1.00 50.04  ? 954  ASP A CG  1 
ATOM 6170 O OD1 . ASP A 1 954  ? 158.380 176.638 155.984 1.00 48.33  ? 954  ASP A OD1 1 
ATOM 6171 O OD2 . ASP A 1 954  ? 158.913 175.192 154.426 1.00 47.97  ? 954  ASP A OD2 1 
ATOM 6172 N N   . SER A 1 955  ? 158.811 174.175 160.081 1.00 59.13  ? 955  SER A N   1 
ATOM 6173 C CA  . SER A 1 955  ? 158.933 173.280 161.226 1.00 61.71  ? 955  SER A CA  1 
ATOM 6174 C C   . SER A 1 955  ? 157.587 172.631 161.503 1.00 61.65  ? 955  SER A C   1 
ATOM 6175 O O   . SER A 1 955  ? 156.657 173.305 161.957 1.00 60.02  ? 955  SER A O   1 
ATOM 6176 C CB  . SER A 1 955  ? 159.426 174.035 162.465 1.00 59.53  ? 955  SER A CB  1 
ATOM 6177 O OG  . SER A 1 955  ? 160.734 174.542 162.267 1.00 60.88  ? 955  SER A OG  1 
ATOM 6178 N N   . SER A 1 956  ? 157.497 171.326 161.241 1.00 66.16  ? 956  SER A N   1 
ATOM 6179 C CA  . SER A 1 956  ? 156.312 170.494 161.508 1.00 66.91  ? 956  SER A CA  1 
ATOM 6180 C C   . SER A 1 956  ? 155.087 171.187 160.908 1.00 68.54  ? 956  SER A C   1 
ATOM 6181 O O   . SER A 1 956  ? 155.161 171.664 159.768 1.00 65.81  ? 956  SER A O   1 
ATOM 6182 C CB  . SER A 1 956  ? 156.236 170.201 163.000 1.00 66.15  ? 956  SER A CB  1 
ATOM 6183 O OG  . SER A 1 956  ? 155.998 171.382 163.746 1.00 67.28  ? 956  SER A OG  1 
ATOM 6184 N N   . THR A 1 957  ? 153.969 171.268 161.623 1.00 72.16  ? 957  THR A N   1 
ATOM 6185 C CA  . THR A 1 957  ? 152.741 171.872 161.118 1.00 72.47  ? 957  THR A CA  1 
ATOM 6186 C C   . THR A 1 957  ? 151.817 172.128 162.305 1.00 72.10  ? 957  THR A C   1 
ATOM 6187 O O   . THR A 1 957  ? 152.224 172.002 163.465 1.00 71.53  ? 957  THR A O   1 
ATOM 6188 C CB  . THR A 1 957  ? 152.082 170.979 160.059 1.00 74.10  ? 957  THR A CB  1 
ATOM 6189 O OG1 . THR A 1 957  ? 150.978 171.672 159.464 1.00 73.88  ? 957  THR A OG1 1 
ATOM 6190 C CG2 . THR A 1 957  ? 151.590 169.679 160.682 1.00 73.19  ? 957  THR A CG2 1 
ATOM 6191 N N   . LYS A 1 958  ? 150.569 172.500 162.008 1.00 73.74  ? 958  LYS A N   1 
ATOM 6192 C CA  . LYS A 1 958  ? 149.536 172.735 163.020 1.00 74.68  ? 958  LYS A CA  1 
ATOM 6193 C C   . LYS A 1 958  ? 149.924 173.852 163.984 1.00 75.38  ? 958  LYS A C   1 
ATOM 6194 O O   . LYS A 1 958  ? 149.527 173.846 165.152 1.00 74.54  ? 958  LYS A O   1 
ATOM 6195 C CB  . LYS A 1 958  ? 149.209 171.452 163.792 1.00 73.90  ? 958  LYS A CB  1 
ATOM 6196 C CG  . LYS A 1 958  ? 148.656 170.333 162.926 1.00 74.18  ? 958  LYS A CG  1 
ATOM 6197 C CD  . LYS A 1 958  ? 147.282 170.686 162.381 1.00 76.06  ? 958  LYS A CD  1 
ATOM 6198 C CE  . LYS A 1 958  ? 146.695 169.536 161.580 1.00 75.44  ? 958  LYS A CE  1 
ATOM 6199 N NZ  . LYS A 1 958  ? 145.367 169.883 161.003 1.00 75.28  ? 958  LYS A NZ  1 
ATOM 6200 N N   . SER A 1 959  ? 150.698 174.820 163.503 1.00 69.66  ? 959  SER A N   1 
ATOM 6201 C CA  . SER A 1 959  ? 151.093 175.976 164.291 1.00 67.87  ? 959  SER A CA  1 
ATOM 6202 C C   . SER A 1 959  ? 150.807 177.242 163.497 1.00 65.56  ? 959  SER A C   1 
ATOM 6203 O O   . SER A 1 959  ? 150.758 177.228 162.265 1.00 66.18  ? 959  SER A O   1 
ATOM 6204 C CB  . SER A 1 959  ? 152.578 175.917 164.679 1.00 65.87  ? 959  SER A CB  1 
ATOM 6205 O OG  . SER A 1 959  ? 153.401 176.376 163.622 1.00 64.64  ? 959  SER A OG  1 
ATOM 6206 N N   . GLN A 1 960  ? 150.611 178.345 164.224 1.00 58.63  ? 960  GLN A N   1 
ATOM 6207 C CA  . GLN A 1 960  ? 150.309 179.613 163.568 1.00 60.39  ? 960  GLN A CA  1 
ATOM 6208 C C   . GLN A 1 960  ? 151.474 180.081 162.704 1.00 62.34  ? 960  GLN A C   1 
ATOM 6209 O O   . GLN A 1 960  ? 151.269 180.615 161.608 1.00 59.87  ? 960  GLN A O   1 
ATOM 6210 C CB  . GLN A 1 960  ? 149.951 180.673 164.609 1.00 59.92  ? 960  GLN A CB  1 
ATOM 6211 C CG  . GLN A 1 960  ? 149.552 182.011 164.011 1.00 60.55  ? 960  GLN A CG  1 
ATOM 6212 C CD  . GLN A 1 960  ? 148.309 181.914 163.147 1.00 62.43  ? 960  GLN A CD  1 
ATOM 6213 O OE1 . GLN A 1 960  ? 148.389 181.946 161.919 1.00 61.87  ? 960  GLN A OE1 1 
ATOM 6214 N NE2 . GLN A 1 960  ? 147.151 181.797 163.786 1.00 61.75  ? 960  GLN A NE2 1 
ATOM 6215 N N   . SER A 1 961  ? 152.707 179.897 163.185 1.00 57.52  ? 961  SER A N   1 
ATOM 6216 C CA  . SER A 1 961  ? 153.873 180.276 162.394 1.00 55.58  ? 961  SER A CA  1 
ATOM 6217 C C   . SER A 1 961  ? 153.952 179.467 161.106 1.00 57.70  ? 961  SER A C   1 
ATOM 6218 O O   . SER A 1 961  ? 154.201 180.023 160.028 1.00 58.08  ? 961  SER A O   1 
ATOM 6219 C CB  . SER A 1 961  ? 155.145 180.093 163.218 1.00 53.26  ? 961  SER A CB  1 
ATOM 6220 O OG  . SER A 1 961  ? 155.372 178.726 163.511 1.00 54.29  ? 961  SER A OG  1 
ATOM 6221 N N   . GLN A 1 962  ? 153.741 178.152 161.196 1.00 53.96  ? 962  GLN A N   1 
ATOM 6222 C CA  . GLN A 1 962  ? 153.724 177.333 159.991 1.00 53.40  ? 962  GLN A CA  1 
ATOM 6223 C C   . GLN A 1 962  ? 152.545 177.694 159.100 1.00 53.48  ? 962  GLN A C   1 
ATOM 6224 O O   . GLN A 1 962  ? 152.659 177.664 157.871 1.00 54.46  ? 962  GLN A O   1 
ATOM 6225 C CB  . GLN A 1 962  ? 153.693 175.850 160.353 1.00 55.55  ? 962  GLN A CB  1 
ATOM 6226 C CG  . GLN A 1 962  ? 154.032 174.940 159.185 1.00 57.19  ? 962  GLN A CG  1 
ATOM 6227 C CD  . GLN A 1 962  ? 155.276 175.389 158.443 1.00 56.29  ? 962  GLN A CD  1 
ATOM 6228 O OE1 . GLN A 1 962  ? 156.335 175.578 159.040 1.00 55.85  ? 962  GLN A OE1 1 
ATOM 6229 N NE2 . GLN A 1 962  ? 155.154 175.557 157.133 1.00 53.42  ? 962  GLN A NE2 1 
ATOM 6230 N N   . ASN A 1 963  ? 151.405 178.041 159.700 1.00 54.11  ? 963  ASN A N   1 
ATOM 6231 C CA  . ASN A 1 963  ? 150.277 178.516 158.907 1.00 54.28  ? 963  ASN A CA  1 
ATOM 6232 C C   . ASN A 1 963  ? 150.623 179.813 158.187 1.00 52.65  ? 963  ASN A C   1 
ATOM 6233 O O   . ASN A 1 963  ? 150.249 180.004 157.026 1.00 50.42  ? 963  ASN A O   1 
ATOM 6234 C CB  . ASN A 1 963  ? 149.047 178.700 159.794 1.00 55.79  ? 963  ASN A CB  1 
ATOM 6235 C CG  . ASN A 1 963  ? 148.477 177.381 160.276 1.00 56.13  ? 963  ASN A CG  1 
ATOM 6236 O OD1 . ASN A 1 963  ? 148.391 176.415 159.519 1.00 55.58  ? 963  ASN A OD1 1 
ATOM 6237 N ND2 . ASN A 1 963  ? 148.085 177.334 161.544 1.00 55.20  ? 963  ASN A ND2 1 
ATOM 6238 N N   . SER A 1 964  ? 151.346 180.714 158.857 1.00 50.11  ? 964  SER A N   1 
ATOM 6239 C CA  . SER A 1 964  ? 151.764 181.956 158.212 1.00 51.95  ? 964  SER A CA  1 
ATOM 6240 C C   . SER A 1 964  ? 152.721 181.687 157.056 1.00 50.05  ? 964  SER A C   1 
ATOM 6241 O O   . SER A 1 964  ? 152.605 182.299 155.986 1.00 46.73  ? 964  SER A O   1 
ATOM 6242 C CB  . SER A 1 964  ? 152.409 182.888 159.238 1.00 50.95  ? 964  SER A CB  1 
ATOM 6243 O OG  . SER A 1 964  ? 152.853 184.088 158.631 1.00 49.07  ? 964  SER A OG  1 
ATOM 6244 N N   . ARG A 1 965  ? 153.676 180.776 157.252 1.00 45.74  ? 965  ARG A N   1 
ATOM 6245 C CA  . ARG A 1 965  ? 154.609 180.440 156.178 1.00 42.01  ? 965  ARG A CA  1 
ATOM 6246 C C   . ARG A 1 965  ? 153.887 179.793 155.001 1.00 43.35  ? 965  ARG A C   1 
ATOM 6247 O O   . ARG A 1 965  ? 154.178 180.096 153.837 1.00 42.39  ? 965  ARG A O   1 
ATOM 6248 C CB  . ARG A 1 965  ? 155.704 179.521 156.714 1.00 39.00  ? 965  ARG A CB  1 
ATOM 6249 C CG  . ARG A 1 965  ? 156.912 180.261 157.256 1.00 41.17  ? 965  ARG A CG  1 
ATOM 6250 C CD  . ARG A 1 965  ? 157.920 179.300 157.851 1.00 39.58  ? 965  ARG A CD  1 
ATOM 6251 N NE  . ARG A 1 965  ? 157.349 178.558 158.967 1.00 41.35  ? 965  ARG A NE  1 
ATOM 6252 C CZ  . ARG A 1 965  ? 157.683 178.738 160.237 1.00 43.11  ? 965  ARG A CZ  1 
ATOM 6253 N NH1 . ARG A 1 965  ? 158.590 179.633 160.593 1.00 42.12  ? 965  ARG A NH1 1 
ATOM 6254 N NH2 . ARG A 1 965  ? 157.097 177.997 161.173 1.00 42.91  ? 965  ARG A NH2 1 
ATOM 6255 N N   . GLN A 1 966  ? 152.938 178.898 155.286 1.00 49.60  ? 966  GLN A N   1 
ATOM 6256 C CA  . GLN A 1 966  ? 152.159 178.268 154.227 1.00 45.65  ? 966  GLN A CA  1 
ATOM 6257 C C   . GLN A 1 966  ? 151.312 179.297 153.488 1.00 43.37  ? 966  GLN A C   1 
ATOM 6258 O O   . GLN A 1 966  ? 151.152 179.220 152.264 1.00 42.36  ? 966  GLN A O   1 
ATOM 6259 C CB  . GLN A 1 966  ? 151.284 177.163 154.824 1.00 45.49  ? 966  GLN A CB  1 
ATOM 6260 C CG  . GLN A 1 966  ? 150.414 176.414 153.825 1.00 47.26  ? 966  GLN A CG  1 
ATOM 6261 C CD  . GLN A 1 966  ? 151.162 176.032 152.564 1.00 49.53  ? 966  GLN A CD  1 
ATOM 6262 O OE1 . GLN A 1 966  ? 150.705 176.300 151.453 1.00 46.86  ? 966  GLN A OE1 1 
ATOM 6263 N NE2 . GLN A 1 966  ? 152.311 175.390 152.730 1.00 51.17  ? 966  GLN A NE2 1 
ATOM 6264 N N   . ARG A 1 967  ? 150.766 180.273 154.217 1.00 45.23  ? 967  ARG A N   1 
ATOM 6265 C CA  . ARG A 1 967  ? 150.026 181.353 153.577 1.00 47.71  ? 967  ARG A CA  1 
ATOM 6266 C C   . ARG A 1 967  ? 150.930 182.177 152.674 1.00 48.30  ? 967  ARG A C   1 
ATOM 6267 O O   . ARG A 1 967  ? 150.514 182.602 151.594 1.00 48.08  ? 967  ARG A O   1 
ATOM 6268 C CB  . ARG A 1 967  ? 149.370 182.243 154.633 1.00 48.08  ? 967  ARG A CB  1 
ATOM 6269 C CG  . ARG A 1 967  ? 147.874 182.027 154.789 1.00 48.71  ? 967  ARG A CG  1 
ATOM 6270 C CD  . ARG A 1 967  ? 147.267 183.026 155.762 1.00 47.78  ? 967  ARG A CD  1 
ATOM 6271 N NE  . ARG A 1 967  ? 147.969 183.053 157.040 1.00 51.24  ? 967  ARG A NE  1 
ATOM 6272 C CZ  . ARG A 1 967  ? 147.669 182.280 158.075 1.00 51.03  ? 967  ARG A CZ  1 
ATOM 6273 N NH1 . ARG A 1 967  ? 146.683 181.400 158.017 1.00 50.49  ? 967  ARG A NH1 1 
ATOM 6274 N NH2 . ARG A 1 967  ? 148.374 182.395 159.197 1.00 48.99  ? 967  ARG A NH2 1 
ATOM 6275 N N   . LEU A 1 968  ? 152.166 182.431 153.110 1.00 45.17  ? 968  LEU A N   1 
ATOM 6276 C CA  . LEU A 1 968  ? 153.114 183.154 152.267 1.00 39.50  ? 968  LEU A CA  1 
ATOM 6277 C C   . LEU A 1 968  ? 153.424 182.372 150.995 1.00 36.75  ? 968  LEU A C   1 
ATOM 6278 O O   . LEU A 1 968  ? 153.497 182.947 149.899 1.00 38.22  ? 968  LEU A O   1 
ATOM 6279 C CB  . LEU A 1 968  ? 154.392 183.444 153.053 1.00 36.91  ? 968  LEU A CB  1 
ATOM 6280 C CG  . LEU A 1 968  ? 154.358 184.704 153.921 1.00 37.97  ? 968  LEU A CG  1 
ATOM 6281 C CD1 . LEU A 1 968  ? 155.705 184.948 154.578 1.00 38.71  ? 968  LEU A CD1 1 
ATOM 6282 C CD2 . LEU A 1 968  ? 153.937 185.909 153.096 1.00 35.46  ? 968  LEU A CD2 1 
ATOM 6283 N N   . ILE A 1 969  ? 153.594 181.053 151.123 1.00 35.27  ? 969  ILE A N   1 
ATOM 6284 C CA  . ILE A 1 969  ? 153.780 180.200 149.949 1.00 34.26  ? 969  ILE A CA  1 
ATOM 6285 C C   . ILE A 1 969  ? 152.582 180.318 149.012 1.00 33.58  ? 969  ILE A C   1 
ATOM 6286 O O   . ILE A 1 969  ? 152.733 180.413 147.788 1.00 33.41  ? 969  ILE A O   1 
ATOM 6287 C CB  . ILE A 1 969  ? 154.013 178.739 150.375 1.00 34.33  ? 969  ILE A CB  1 
ATOM 6288 C CG1 . ILE A 1 969  ? 155.246 178.621 151.271 1.00 34.22  ? 969  ILE A CG1 1 
ATOM 6289 C CG2 . ILE A 1 969  ? 154.161 177.847 149.156 1.00 36.55  ? 969  ILE A CG2 1 
ATOM 6290 C CD1 . ILE A 1 969  ? 156.520 179.055 150.602 1.00 34.34  ? 969  ILE A CD1 1 
ATOM 6291 N N   . ASP A 1 970  ? 151.372 180.294 149.575 1.00 39.77  ? 970  ASP A N   1 
ATOM 6292 C CA  . ASP A 1 970  ? 150.168 180.379 148.753 1.00 39.86  ? 970  ASP A CA  1 
ATOM 6293 C C   . ASP A 1 970  ? 150.054 181.729 148.053 1.00 37.15  ? 970  ASP A C   1 
ATOM 6294 O O   . ASP A 1 970  ? 149.636 181.793 146.893 1.00 42.45  ? 970  ASP A O   1 
ATOM 6295 C CB  . ASP A 1 970  ? 148.929 180.106 149.603 1.00 43.28  ? 970  ASP A CB  1 
ATOM 6296 C CG  . ASP A 1 970  ? 148.829 178.658 150.032 1.00 44.37  ? 970  ASP A CG  1 
ATOM 6297 O OD1 . ASP A 1 970  ? 149.606 177.826 149.515 1.00 42.28  ? 970  ASP A OD1 1 
ATOM 6298 O OD2 . ASP A 1 970  ? 147.984 178.355 150.898 1.00 43.66  ? 970  ASP A OD2 1 
ATOM 6299 N N   . ASP A 1 971  ? 150.396 182.822 148.741 1.00 31.97  ? 971  ASP A N   1 
ATOM 6300 C CA  . ASP A 1 971  ? 150.362 184.129 148.089 1.00 34.60  ? 971  ASP A CA  1 
ATOM 6301 C C   . ASP A 1 971  ? 151.394 184.210 146.973 1.00 38.84  ? 971  ASP A C   1 
ATOM 6302 O O   . ASP A 1 971  ? 151.143 184.828 145.931 1.00 38.79  ? 971  ASP A O   1 
ATOM 6303 C CB  . ASP A 1 971  ? 150.582 185.258 149.099 1.00 36.84  ? 971  ASP A CB  1 
ATOM 6304 C CG  . ASP A 1 971  ? 149.766 185.084 150.361 1.00 40.51  ? 971  ASP A CG  1 
ATOM 6305 O OD1 . ASP A 1 971  ? 148.582 184.703 150.259 1.00 44.60  ? 971  ASP A OD1 1 
ATOM 6306 O OD2 . ASP A 1 971  ? 150.309 185.337 151.458 1.00 38.62  ? 971  ASP A OD2 1 
ATOM 6307 N N   . PHE A 1 972  ? 152.567 183.603 147.173 1.00 30.46  ? 972  PHE A N   1 
ATOM 6308 C CA  . PHE A 1 972  ? 153.553 183.556 146.097 1.00 27.12  ? 972  PHE A CA  1 
ATOM 6309 C C   . PHE A 1 972  ? 153.031 182.769 144.901 1.00 27.20  ? 972  PHE A C   1 
ATOM 6310 O O   . PHE A 1 972  ? 153.145 183.216 143.754 1.00 27.65  ? 972  PHE A O   1 
ATOM 6311 C CB  . PHE A 1 972  ? 154.861 182.951 146.606 1.00 27.53  ? 972  PHE A CB  1 
ATOM 6312 C CG  . PHE A 1 972  ? 155.736 182.394 145.518 1.00 23.69  ? 972  PHE A CG  1 
ATOM 6313 C CD1 . PHE A 1 972  ? 156.440 183.237 144.678 1.00 16.76  ? 972  PHE A CD1 1 
ATOM 6314 C CD2 . PHE A 1 972  ? 155.860 181.026 145.342 1.00 26.30  ? 972  PHE A CD2 1 
ATOM 6315 C CE1 . PHE A 1 972  ? 157.245 182.727 143.680 1.00 20.61  ? 972  PHE A CE1 1 
ATOM 6316 C CE2 . PHE A 1 972  ? 156.664 180.512 144.346 1.00 21.76  ? 972  PHE A CE2 1 
ATOM 6317 C CZ  . PHE A 1 972  ? 157.357 181.364 143.515 1.00 18.51  ? 972  PHE A CZ  1 
ATOM 6318 N N   . GLN A 1 973  ? 152.439 181.599 145.150 1.00 31.08  ? 973  GLN A N   1 
ATOM 6319 C CA  . GLN A 1 973  ? 152.020 180.729 144.056 1.00 30.21  ? 973  GLN A CA  1 
ATOM 6320 C C   . GLN A 1 973  ? 150.780 181.254 143.343 1.00 35.17  ? 973  GLN A C   1 
ATOM 6321 O O   . GLN A 1 973  ? 150.590 180.979 142.153 1.00 36.12  ? 973  GLN A O   1 
ATOM 6322 C CB  . GLN A 1 973  ? 151.761 179.317 144.579 1.00 31.58  ? 973  GLN A CB  1 
ATOM 6323 C CG  . GLN A 1 973  ? 152.997 178.596 145.076 1.00 33.01  ? 973  GLN A CG  1 
ATOM 6324 C CD  . GLN A 1 973  ? 152.676 177.213 145.598 1.00 35.47  ? 973  GLN A CD  1 
ATOM 6325 O OE1 . GLN A 1 973  ? 151.519 176.809 145.654 1.00 37.49  ? 973  GLN A OE1 1 
ATOM 6326 N NE2 . GLN A 1 973  ? 153.690 176.483 145.973 1.00 37.51  ? 973  GLN A NE2 1 
ATOM 6327 N N   . ALA A 1 974  ? 149.925 181.995 144.047 1.00 35.70  ? 974  ALA A N   1 
ATOM 6328 C CA  . ALA A 1 974  ? 148.653 182.418 143.473 1.00 33.43  ? 974  ALA A CA  1 
ATOM 6329 C C   . ALA A 1 974  ? 148.819 183.575 142.497 1.00 36.43  ? 974  ALA A C   1 
ATOM 6330 O O   . ALA A 1 974  ? 148.097 183.649 141.496 1.00 41.26  ? 974  ALA A O   1 
ATOM 6331 C CB  . ALA A 1 974  ? 147.678 182.800 144.587 1.00 36.21  ? 974  ALA A CB  1 
ATOM 6332 N N   . GLN A 1 975  ? 149.751 184.479 142.764 1.00 34.90  ? 975  GLN A N   1 
ATOM 6333 C CA  . GLN A 1 975  ? 149.896 185.672 141.935 1.00 36.83  ? 975  GLN A CA  1 
ATOM 6334 C C   . GLN A 1 975  ? 150.383 185.281 140.547 1.00 38.32  ? 975  GLN A C   1 
ATOM 6335 O O   . GLN A 1 975  ? 151.481 184.724 140.420 1.00 39.30  ? 975  GLN A O   1 
ATOM 6336 C CB  . GLN A 1 975  ? 150.867 186.652 142.588 1.00 35.59  ? 975  GLN A CB  1 
ATOM 6337 C CG  . GLN A 1 975  ? 150.948 188.015 141.910 1.00 37.43  ? 975  GLN A CG  1 
ATOM 6338 C CD  . GLN A 1 975  ? 151.932 188.044 140.755 1.00 40.48  ? 975  GLN A CD  1 
ATOM 6339 O OE1 . GLN A 1 975  ? 152.921 187.310 140.748 1.00 41.66  ? 975  GLN A OE1 1 
ATOM 6340 N NE2 . GLN A 1 975  ? 151.664 188.893 139.770 1.00 39.43  ? 975  GLN A NE2 1 
ATOM 6341 N N   . PRO A 1 976  ? 149.624 185.558 139.489 1.00 39.67  ? 976  PRO A N   1 
ATOM 6342 C CA  . PRO A 1 976  ? 150.044 185.134 138.149 1.00 40.06  ? 976  PRO A CA  1 
ATOM 6343 C C   . PRO A 1 976  ? 151.188 185.981 137.618 1.00 40.66  ? 976  PRO A C   1 
ATOM 6344 O O   . PRO A 1 976  ? 151.217 187.203 137.787 1.00 37.29  ? 976  PRO A O   1 
ATOM 6345 C CB  . PRO A 1 976  ? 148.777 185.326 137.307 1.00 41.50  ? 976  PRO A CB  1 
ATOM 6346 C CG  . PRO A 1 976  ? 148.030 186.407 138.014 1.00 39.05  ? 976  PRO A CG  1 
ATOM 6347 C CD  . PRO A 1 976  ? 148.302 186.208 139.478 1.00 38.35  ? 976  PRO A CD  1 
ATOM 6348 N N   . GLY A 1 977  ? 152.133 185.318 136.970 1.00 36.66  ? 977  GLY A N   1 
ATOM 6349 C CA  . GLY A 1 977  ? 153.241 185.983 136.319 1.00 33.59  ? 977  GLY A CA  1 
ATOM 6350 C C   . GLY A 1 977  ? 154.574 185.670 136.976 1.00 33.18  ? 977  GLY A C   1 
ATOM 6351 O O   . GLY A 1 977  ? 154.713 184.744 137.777 1.00 31.39  ? 977  GLY A O   1 
ATOM 6352 N N   . PHE A 1 978  ? 155.569 186.475 136.616 1.00 23.98  ? 978  PHE A N   1 
ATOM 6353 C CA  . PHE A 1 978  ? 156.923 186.292 137.115 1.00 17.36  ? 978  PHE A CA  1 
ATOM 6354 C C   . PHE A 1 978  ? 156.999 186.621 138.599 1.00 20.10  ? 978  PHE A C   1 
ATOM 6355 O O   . PHE A 1 978  ? 156.428 187.610 139.065 1.00 24.60  ? 978  PHE A O   1 
ATOM 6356 C CB  . PHE A 1 978  ? 157.896 187.170 136.326 1.00 19.30  ? 978  PHE A CB  1 
ATOM 6357 C CG  . PHE A 1 978  ? 159.277 187.231 136.904 1.00 21.92  ? 978  PHE A CG  1 
ATOM 6358 C CD1 . PHE A 1 978  ? 160.153 186.172 136.751 1.00 20.51  ? 978  PHE A CD1 1 
ATOM 6359 C CD2 . PHE A 1 978  ? 159.707 188.358 137.583 1.00 19.71  ? 978  PHE A CD2 1 
ATOM 6360 C CE1 . PHE A 1 978  ? 161.426 186.230 137.278 1.00 16.55  ? 978  PHE A CE1 1 
ATOM 6361 C CE2 . PHE A 1 978  ? 160.980 188.420 138.110 1.00 16.88  ? 978  PHE A CE2 1 
ATOM 6362 C CZ  . PHE A 1 978  ? 161.840 187.356 137.956 1.00 15.61  ? 978  PHE A CZ  1 
ATOM 6363 N N   . GLY A 1 979  ? 157.711 185.781 139.340 1.00 15.48  ? 979  GLY A N   1 
ATOM 6364 C CA  . GLY A 1 979  ? 157.888 185.994 140.762 1.00 13.80  ? 979  GLY A CA  1 
ATOM 6365 C C   . GLY A 1 979  ? 159.050 185.182 141.277 1.00 13.98  ? 979  GLY A C   1 
ATOM 6366 O O   . GLY A 1 979  ? 159.383 184.128 140.728 1.00 19.05  ? 979  GLY A O   1 
ATOM 6367 N N   . VAL A 1 980  ? 159.675 185.679 142.341 1.00 8.02   ? 980  VAL A N   1 
ATOM 6368 C CA  . VAL A 1 980  ? 160.836 185.039 142.943 1.00 4.12   ? 980  VAL A CA  1 
ATOM 6369 C C   . VAL A 1 980  ? 160.580 184.855 144.430 1.00 8.02   ? 980  VAL A C   1 
ATOM 6370 O O   . VAL A 1 980  ? 160.049 185.751 145.095 1.00 19.25  ? 980  VAL A O   1 
ATOM 6371 C CB  . VAL A 1 980  ? 162.125 185.857 142.718 1.00 5.95   ? 980  VAL A CB  1 
ATOM 6372 C CG1 . VAL A 1 980  ? 163.333 185.035 143.095 1.00 8.02   ? 980  VAL A CG1 1 
ATOM 6373 C CG2 . VAL A 1 980  ? 162.229 186.310 141.277 1.00 8.62   ? 980  VAL A CG2 1 
ATOM 6374 N N   . ILE A 1 981  ? 160.950 183.688 144.949 1.00 2.94   ? 981  ILE A N   1 
ATOM 6375 C CA  . ILE A 1 981  ? 160.895 183.407 146.377 1.00 6.66   ? 981  ILE A CA  1 
ATOM 6376 C C   . ILE A 1 981  ? 162.254 182.878 146.810 1.00 4.14   ? 981  ILE A C   1 
ATOM 6377 O O   . ILE A 1 981  ? 162.893 182.106 146.085 1.00 10.33  ? 981  ILE A O   1 
ATOM 6378 C CB  . ILE A 1 981  ? 159.769 182.409 146.728 1.00 10.00  ? 981  ILE A CB  1 
ATOM 6379 C CG1 . ILE A 1 981  ? 159.644 182.255 148.244 1.00 8.31   ? 981  ILE A CG1 1 
ATOM 6380 C CG2 . ILE A 1 981  ? 159.998 181.059 146.065 1.00 6.08   ? 981  ILE A CG2 1 
ATOM 6381 C CD1 . ILE A 1 981  ? 158.450 181.445 148.673 1.00 9.02   ? 981  ILE A CD1 1 
ATOM 6382 N N   . ILE A 1 982  ? 162.713 183.320 147.975 1.00 0.00   ? 982  ILE A N   1 
ATOM 6383 C CA  . ILE A 1 982  ? 163.985 182.888 148.538 1.00 6.00   ? 982  ILE A CA  1 
ATOM 6384 C C   . ILE A 1 982  ? 163.681 181.940 149.687 1.00 2.83   ? 982  ILE A C   1 
ATOM 6385 O O   . ILE A 1 982  ? 163.066 182.337 150.683 1.00 7.90   ? 982  ILE A O   1 
ATOM 6386 C CB  . ILE A 1 982  ? 164.833 184.078 149.007 1.00 6.16   ? 982  ILE A CB  1 
ATOM 6387 C CG1 . ILE A 1 982  ? 164.742 185.223 147.997 1.00 3.57   ? 982  ILE A CG1 1 
ATOM 6388 C CG2 . ILE A 1 982  ? 166.276 183.654 149.190 1.00 1.13   ? 982  ILE A CG2 1 
ATOM 6389 C CD1 . ILE A 1 982  ? 165.645 186.390 148.315 1.00 0.61   ? 982  ILE A CD1 1 
ATOM 6390 N N   . LEU A 1 983  ? 164.108 180.689 149.549 1.00 6.31   ? 983  LEU A N   1 
ATOM 6391 C CA  . LEU A 1 983  ? 163.842 179.660 150.539 1.00 7.36   ? 983  LEU A CA  1 
ATOM 6392 C C   . LEU A 1 983  ? 165.147 179.036 151.008 1.00 8.64   ? 983  LEU A C   1 
ATOM 6393 O O   . LEU A 1 983  ? 166.167 179.090 150.315 1.00 13.63  ? 983  LEU A O   1 
ATOM 6394 C CB  . LEU A 1 983  ? 162.925 178.565 149.980 1.00 8.88   ? 983  LEU A CB  1 
ATOM 6395 C CG  . LEU A 1 983  ? 161.560 179.000 149.450 1.00 7.97   ? 983  LEU A CG  1 
ATOM 6396 C CD1 . LEU A 1 983  ? 161.084 178.045 148.371 1.00 8.76   ? 983  LEU A CD1 1 
ATOM 6397 C CD2 . LEU A 1 983  ? 160.551 179.080 150.580 1.00 9.68   ? 983  LEU A CD2 1 
ATOM 6398 N N   . SER A 1 984  ? 165.105 178.452 152.199 1.00 9.90   ? 984  SER A N   1 
ATOM 6399 C CA  . SER A 1 984  ? 166.229 177.698 152.728 1.00 13.56  ? 984  SER A CA  1 
ATOM 6400 C C   . SER A 1 984  ? 166.036 176.219 152.425 1.00 20.15  ? 984  SER A C   1 
ATOM 6401 O O   . SER A 1 984  ? 164.909 175.716 152.420 1.00 24.62  ? 984  SER A O   1 
ATOM 6402 C CB  . SER A 1 984  ? 166.367 177.916 154.235 1.00 13.63  ? 984  SER A CB  1 
ATOM 6403 O OG  . SER A 1 984  ? 167.487 177.220 154.748 1.00 22.82  ? 984  SER A OG  1 
ATOM 6404 N N   . THR A 1 985  ? 167.143 175.526 152.160 1.00 22.58  ? 985  THR A N   1 
ATOM 6405 C CA  . THR A 1 985  ? 167.069 174.107 151.840 1.00 21.02  ? 985  THR A CA  1 
ATOM 6406 C C   . THR A 1 985  ? 166.710 173.245 153.042 1.00 25.97  ? 985  THR A C   1 
ATOM 6407 O O   . THR A 1 985  ? 166.412 172.060 152.862 1.00 29.78  ? 985  THR A O   1 
ATOM 6408 C CB  . THR A 1 985  ? 168.395 173.627 151.251 1.00 19.87  ? 985  THR A CB  1 
ATOM 6409 O OG1 . THR A 1 985  ? 169.440 173.806 152.214 1.00 25.19  ? 985  THR A OG1 1 
ATOM 6410 C CG2 . THR A 1 985  ? 168.735 174.409 149.996 1.00 19.34  ? 985  THR A CG2 1 
ATOM 6411 N N   . VAL A 1 986  ? 166.732 173.799 154.250 1.00 28.10  ? 986  VAL A N   1 
ATOM 6412 C CA  . VAL A 1 986  ? 166.421 173.028 155.447 1.00 31.13  ? 986  VAL A CA  1 
ATOM 6413 C C   . VAL A 1 986  ? 164.922 172.764 155.503 1.00 33.69  ? 986  VAL A C   1 
ATOM 6414 O O   . VAL A 1 986  ? 164.102 173.656 155.251 1.00 29.50  ? 986  VAL A O   1 
ATOM 6415 C CB  . VAL A 1 986  ? 166.920 173.755 156.710 1.00 28.58  ? 986  VAL A CB  1 
ATOM 6416 C CG1 . VAL A 1 986  ? 168.427 173.912 156.668 1.00 29.16  ? 986  VAL A CG1 1 
ATOM 6417 C CG2 . VAL A 1 986  ? 166.256 175.112 156.860 1.00 27.35  ? 986  VAL A CG2 1 
ATOM 6418 N N   . ALA A 1 987  ? 164.562 171.521 155.810 1.00 46.80  ? 987  ALA A N   1 
ATOM 6419 C CA  . ALA A 1 987  ? 163.160 171.129 155.921 1.00 49.21  ? 987  ALA A CA  1 
ATOM 6420 C C   . ALA A 1 987  ? 163.086 169.940 156.867 1.00 52.27  ? 987  ALA A C   1 
ATOM 6421 O O   . ALA A 1 987  ? 163.411 168.816 156.475 1.00 50.07  ? 987  ALA A O   1 
ATOM 6422 C CB  . ALA A 1 987  ? 162.570 170.785 154.556 1.00 46.96  ? 987  ALA A CB  1 
ATOM 6423 N N   . VAL A 1 988  ? 162.665 170.190 158.110 1.00 63.22  ? 988  VAL A N   1 
ATOM 6424 C CA  . VAL A 1 988  ? 162.577 169.119 159.094 1.00 64.64  ? 988  VAL A CA  1 
ATOM 6425 C C   . VAL A 1 988  ? 161.514 168.097 158.711 1.00 67.49  ? 988  VAL A C   1 
ATOM 6426 O O   . VAL A 1 988  ? 161.597 166.934 159.126 1.00 66.72  ? 988  VAL A O   1 
ATOM 6427 C CB  . VAL A 1 988  ? 162.316 169.711 160.494 1.00 64.74  ? 988  VAL A CB  1 
ATOM 6428 C CG1 . VAL A 1 988  ? 160.957 170.389 160.547 1.00 63.98  ? 988  VAL A CG1 1 
ATOM 6429 C CG2 . VAL A 1 988  ? 162.443 168.642 161.575 1.00 64.72  ? 988  VAL A CG2 1 
ATOM 6430 N N   . GLY A 1 989  ? 160.525 168.491 157.914 1.00 70.98  ? 989  GLY A N   1 
ATOM 6431 C CA  . GLY A 1 989  ? 159.495 167.566 157.482 1.00 71.06  ? 989  GLY A CA  1 
ATOM 6432 C C   . GLY A 1 989  ? 158.871 168.010 156.181 1.00 71.71  ? 989  GLY A C   1 
ATOM 6433 O O   . GLY A 1 989  ? 158.939 169.184 155.802 1.00 70.14  ? 989  GLY A O   1 
ATOM 6434 N N   . PHE A 1 990  ? 158.257 167.050 155.496 1.00 72.43  ? 990  PHE A N   1 
ATOM 6435 C CA  . PHE A 1 990  ? 157.602 167.320 154.228 1.00 70.28  ? 990  PHE A CA  1 
ATOM 6436 C C   . PHE A 1 990  ? 156.215 167.919 154.455 1.00 69.90  ? 990  PHE A C   1 
ATOM 6437 O O   . PHE A 1 990  ? 155.651 167.857 155.551 1.00 69.93  ? 990  PHE A O   1 
ATOM 6438 C CB  . PHE A 1 990  ? 157.497 166.041 153.396 1.00 71.52  ? 990  PHE A CB  1 
ATOM 6439 C CG  . PHE A 1 990  ? 158.827 165.413 153.077 1.00 72.08  ? 990  PHE A CG  1 
ATOM 6440 C CD1 . PHE A 1 990  ? 159.856 166.174 152.548 1.00 68.40  ? 990  PHE A CD1 1 
ATOM 6441 C CD2 . PHE A 1 990  ? 159.048 164.064 153.306 1.00 72.46  ? 990  PHE A CD2 1 
ATOM 6442 C CE1 . PHE A 1 990  ? 161.081 165.604 152.253 1.00 70.43  ? 990  PHE A CE1 1 
ATOM 6443 C CE2 . PHE A 1 990  ? 160.273 163.488 153.013 1.00 72.72  ? 990  PHE A CE2 1 
ATOM 6444 C CZ  . PHE A 1 990  ? 161.289 164.259 152.486 1.00 71.32  ? 990  PHE A CZ  1 
ATOM 6445 N N   . GLY A 1 991  ? 155.669 168.509 153.394 1.00 68.45  ? 991  GLY A N   1 
ATOM 6446 C CA  . GLY A 1 991  ? 154.349 169.105 153.457 1.00 68.68  ? 991  GLY A CA  1 
ATOM 6447 C C   . GLY A 1 991  ? 154.270 170.452 152.770 1.00 68.94  ? 991  GLY A C   1 
ATOM 6448 O O   . GLY A 1 991  ? 153.210 170.842 152.270 1.00 70.15  ? 991  GLY A O   1 
ATOM 6449 N N   . VAL A 1 992  ? 155.387 171.171 152.740 1.00 59.84  ? 992  VAL A N   1 
ATOM 6450 C CA  . VAL A 1 992  ? 155.454 172.489 152.120 1.00 56.91  ? 992  VAL A CA  1 
ATOM 6451 C C   . VAL A 1 992  ? 155.828 172.303 150.654 1.00 58.77  ? 992  VAL A C   1 
ATOM 6452 O O   . VAL A 1 992  ? 156.812 171.625 150.333 1.00 57.12  ? 992  VAL A O   1 
ATOM 6453 C CB  . VAL A 1 992  ? 156.464 173.392 152.841 1.00 56.30  ? 992  VAL A CB  1 
ATOM 6454 C CG1 . VAL A 1 992  ? 156.040 173.606 154.287 1.00 58.08  ? 992  VAL A CG1 1 
ATOM 6455 C CG2 . VAL A 1 992  ? 157.866 172.800 152.767 1.00 57.01  ? 992  VAL A CG2 1 
ATOM 6456 N N   . ASN A 1 993  ? 155.038 172.894 149.759 1.00 55.95  ? 993  ASN A N   1 
ATOM 6457 C CA  . ASN A 1 993  ? 155.162 172.633 148.332 1.00 51.09  ? 993  ASN A CA  1 
ATOM 6458 C C   . ASN A 1 993  ? 155.180 173.928 147.528 1.00 50.62  ? 993  ASN A C   1 
ATOM 6459 O O   . ASN A 1 993  ? 154.487 174.893 147.866 1.00 52.53  ? 993  ASN A O   1 
ATOM 6460 C CB  . ASN A 1 993  ? 154.027 171.691 147.854 1.00 51.49  ? 993  ASN A CB  1 
ATOM 6461 C CG  . ASN A 1 993  ? 152.623 172.268 148.066 1.00 57.50  ? 993  ASN A CG  1 
ATOM 6462 O OD1 . ASN A 1 993  ? 152.451 173.418 148.463 1.00 57.45  ? 993  ASN A OD1 1 
ATOM 6463 N ND2 . ASN A 1 993  ? 151.611 171.445 147.811 1.00 54.72  ? 993  ASN A ND2 1 
ATOM 6464 N N   . VAL A 1 994  ? 156.016 173.956 146.492 1.00 40.90  ? 994  VAL A N   1 
ATOM 6465 C CA  . VAL A 1 994  ? 156.028 175.037 145.507 1.00 42.81  ? 994  VAL A CA  1 
ATOM 6466 C C   . VAL A 1 994  ? 156.109 174.390 144.128 1.00 40.62  ? 994  VAL A C   1 
ATOM 6467 O O   . VAL A 1 994  ? 157.188 174.108 143.611 1.00 41.38  ? 994  VAL A O   1 
ATOM 6468 C CB  . VAL A 1 994  ? 157.165 176.037 145.737 1.00 39.42  ? 994  VAL A CB  1 
ATOM 6469 C CG1 . VAL A 1 994  ? 157.016 176.710 147.086 1.00 38.36  ? 994  VAL A CG1 1 
ATOM 6470 C CG2 . VAL A 1 994  ? 158.492 175.346 145.667 1.00 39.89  ? 994  VAL A CG2 1 
ATOM 6471 N N   . GLN A 1 995  ? 154.960 174.154 143.494 1.00 39.86  ? 995  GLN A N   1 
ATOM 6472 C CA  . GLN A 1 995  ? 154.974 173.629 142.133 1.00 36.55  ? 995  GLN A CA  1 
ATOM 6473 C C   . GLN A 1 995  ? 154.768 174.695 141.069 1.00 36.50  ? 995  GLN A C   1 
ATOM 6474 O O   . GLN A 1 995  ? 155.160 174.478 139.918 1.00 39.35  ? 995  GLN A O   1 
ATOM 6475 C CB  . GLN A 1 995  ? 153.906 172.545 141.930 1.00 38.14  ? 995  GLN A CB  1 
ATOM 6476 C CG  . GLN A 1 995  ? 154.099 171.245 142.695 1.00 42.83  ? 995  GLN A CG  1 
ATOM 6477 C CD  . GLN A 1 995  ? 153.615 171.307 144.127 1.00 45.56  ? 995  GLN A CD  1 
ATOM 6478 O OE1 . GLN A 1 995  ? 152.848 172.194 144.504 1.00 39.74  ? 995  GLN A OE1 1 
ATOM 6479 N NE2 . GLN A 1 995  ? 154.044 170.345 144.931 1.00 45.55  ? 995  GLN A NE2 1 
ATOM 6480 N N   . LYS A 1 996  ? 154.159 175.829 141.419 1.00 31.04  ? 996  LYS A N   1 
ATOM 6481 C CA  . LYS A 1 996  ? 153.935 176.891 140.448 1.00 30.62  ? 996  LYS A CA  1 
ATOM 6482 C C   . LYS A 1 996  ? 155.234 177.512 139.957 1.00 32.98  ? 996  LYS A C   1 
ATOM 6483 O O   . LYS A 1 996  ? 155.216 178.249 138.966 1.00 33.97  ? 996  LYS A O   1 
ATOM 6484 C CB  . LYS A 1 996  ? 153.037 177.969 141.052 1.00 33.87  ? 996  LYS A CB  1 
ATOM 6485 C CG  . LYS A 1 996  ? 151.660 177.466 141.444 1.00 33.17  ? 996  LYS A CG  1 
ATOM 6486 C CD  . LYS A 1 996  ? 150.898 176.954 140.236 1.00 33.36  ? 996  LYS A CD  1 
ATOM 6487 C CE  . LYS A 1 996  ? 150.568 178.088 139.280 1.00 35.04  ? 996  LYS A CE  1 
ATOM 6488 N NZ  . LYS A 1 996  ? 149.637 179.079 139.890 1.00 33.30  ? 996  LYS A NZ  1 
ATOM 6489 N N   . ALA A 1 997  ? 156.345 177.237 140.628 1.00 27.24  ? 997  ALA A N   1 
ATOM 6490 C CA  . ALA A 1 997  ? 157.662 177.671 140.193 1.00 20.20  ? 997  ALA A CA  1 
ATOM 6491 C C   . ALA A 1 997  ? 158.394 176.490 139.580 1.00 25.22  ? 997  ALA A C   1 
ATOM 6492 O O   . ALA A 1 997  ? 158.453 175.415 140.183 1.00 27.55  ? 997  ALA A O   1 
ATOM 6493 C CB  . ALA A 1 997  ? 158.464 178.235 141.366 1.00 19.39  ? 997  ALA A CB  1 
ATOM 6494 N N   . ASN A 1 998  ? 158.935 176.681 138.378 1.00 24.47  ? 998  ASN A N   1 
ATOM 6495 C CA  . ASN A 1 998  ? 159.847 175.712 137.784 1.00 18.83  ? 998  ASN A CA  1 
ATOM 6496 C C   . ASN A 1 998  ? 161.132 176.443 137.377 1.00 20.21  ? 998  ASN A C   1 
ATOM 6497 O O   . ASN A 1 998  ? 161.451 176.633 136.205 1.00 25.47  ? 998  ASN A O   1 
ATOM 6498 C CB  . ASN A 1 998  ? 159.156 174.978 136.616 1.00 24.03  ? 998  ASN A CB  1 
ATOM 6499 C CG  . ASN A 1 998  ? 158.925 175.866 135.395 1.00 24.14  ? 998  ASN A CG  1 
ATOM 6500 O OD1 . ASN A 1 998  ? 159.740 175.921 134.476 1.00 19.39  ? 998  ASN A OD1 1 
ATOM 6501 N ND2 . ASN A 1 998  ? 157.812 176.576 135.397 1.00 27.63  ? 998  ASN A ND2 1 
ATOM 6502 N N   . HIS A 1 999  ? 161.918 176.788 138.393 1.00 13.63  ? 999  HIS A N   1 
ATOM 6503 C CA  . HIS A 1 999  ? 163.270 177.316 138.268 1.00 3.89   ? 999  HIS A CA  1 
ATOM 6504 C C   . HIS A 1 999  ? 163.923 177.208 139.636 1.00 5.80   ? 999  HIS A C   1 
ATOM 6505 O O   . HIS A 1 999  ? 163.537 177.926 140.564 1.00 16.02  ? 999  HIS A O   1 
ATOM 6506 C CB  . HIS A 1 999  ? 163.280 178.766 137.780 1.00 2.20   ? 999  HIS A CB  1 
ATOM 6507 C CG  . HIS A 1 999  ? 163.067 178.912 136.307 1.00 9.15   ? 999  HIS A CG  1 
ATOM 6508 N ND1 . HIS A 1 999  ? 161.818 179.087 135.751 1.00 14.08  ? 999  HIS A ND1 1 
ATOM 6509 C CD2 . HIS A 1 999  ? 163.938 178.884 135.271 1.00 7.54   ? 999  HIS A CD2 1 
ATOM 6510 C CE1 . HIS A 1 999  ? 161.931 179.176 134.438 1.00 10.60  ? 999  HIS A CE1 1 
ATOM 6511 N NE2 . HIS A 1 999  ? 163.208 179.055 134.121 1.00 3.84   ? 999  HIS A NE2 1 
ATOM 6512 N N   . VAL A 1 1000 ? 164.900 176.329 139.784 1.00 5.20   ? 1000 VAL A N   1 
ATOM 6513 C CA  . VAL A 1 1000 ? 165.488 176.043 141.083 1.00 5.48   ? 1000 VAL A CA  1 
ATOM 6514 C C   . VAL A 1 1000 ? 166.944 176.483 141.025 1.00 5.53   ? 1000 VAL A C   1 
ATOM 6515 O O   . VAL A 1 1000 ? 167.814 175.738 140.563 1.00 15.73  ? 1000 VAL A O   1 
ATOM 6516 C CB  . VAL A 1 1000 ? 165.355 174.564 141.456 1.00 7.40   ? 1000 VAL A CB  1 
ATOM 6517 C CG1 . VAL A 1 1000 ? 165.954 174.315 142.815 1.00 13.20  ? 1000 VAL A CG1 1 
ATOM 6518 C CG2 . VAL A 1 1000 ? 163.894 174.146 141.436 1.00 5.62   ? 1000 VAL A CG2 1 
ATOM 6519 N N   . ILE A 1 1001 ? 167.214 177.697 141.492 1.00 0.00   ? 1001 ILE A N   1 
ATOM 6520 C CA  . ILE A 1 1001 ? 168.568 178.225 141.575 1.00 3.08   ? 1001 ILE A CA  1 
ATOM 6521 C C   . ILE A 1 1001 ? 169.091 177.951 142.976 1.00 7.12   ? 1001 ILE A C   1 
ATOM 6522 O O   . ILE A 1 1001 ? 168.577 178.491 143.960 1.00 10.81  ? 1001 ILE A O   1 
ATOM 6523 C CB  . ILE A 1 1001 ? 168.623 179.722 141.250 1.00 0.00   ? 1001 ILE A CB  1 
ATOM 6524 C CG1 . ILE A 1 1001 ? 168.052 179.992 139.861 1.00 0.00   ? 1001 ILE A CG1 1 
ATOM 6525 C CG2 . ILE A 1 1001 ? 170.044 180.240 141.378 1.00 3.32   ? 1001 ILE A CG2 1 
ATOM 6526 C CD1 . ILE A 1 1001 ? 167.243 181.244 139.785 1.00 0.00   ? 1001 ILE A CD1 1 
ATOM 6527 N N   . HIS A 1 1002 ? 170.114 177.108 143.069 1.00 6.64   ? 1002 HIS A N   1 
ATOM 6528 C CA  . HIS A 1 1002 ? 170.853 176.923 144.314 1.00 0.04   ? 1002 HIS A CA  1 
ATOM 6529 C C   . HIS A 1 1002 ? 171.985 177.936 144.310 1.00 5.08   ? 1002 HIS A C   1 
ATOM 6530 O O   . HIS A 1 1002 ? 173.094 177.658 143.853 1.00 11.94  ? 1002 HIS A O   1 
ATOM 6531 C CB  . HIS A 1 1002 ? 171.371 175.498 144.439 1.00 6.96   ? 1002 HIS A CB  1 
ATOM 6532 C CG  . HIS A 1 1002 ? 170.291 174.477 144.589 1.00 2.39   ? 1002 HIS A CG  1 
ATOM 6533 N ND1 . HIS A 1 1002 ? 169.837 174.053 145.817 1.00 7.13   ? 1002 HIS A ND1 1 
ATOM 6534 C CD2 . HIS A 1 1002 ? 169.575 173.793 143.666 1.00 0.00   ? 1002 HIS A CD2 1 
ATOM 6535 C CE1 . HIS A 1 1002 ? 168.884 173.156 145.645 1.00 4.14   ? 1002 HIS A CE1 1 
ATOM 6536 N NE2 . HIS A 1 1002 ? 168.709 172.977 144.349 1.00 2.68   ? 1002 HIS A NE2 1 
ATOM 6537 N N   . PHE A 1 1003 ? 171.693 179.139 144.811 1.00 4.26   ? 1003 PHE A N   1 
ATOM 6538 C CA  . PHE A 1 1003 ? 172.721 180.171 144.882 1.00 4.74   ? 1003 PHE A CA  1 
ATOM 6539 C C   . PHE A 1 1003 ? 173.883 179.710 145.749 1.00 4.84   ? 1003 PHE A C   1 
ATOM 6540 O O   . PHE A 1 1003 ? 175.050 179.878 145.380 1.00 9.87   ? 1003 PHE A O   1 
ATOM 6541 C CB  . PHE A 1 1003 ? 172.122 181.470 145.417 1.00 1.45   ? 1003 PHE A CB  1 
ATOM 6542 C CG  . PHE A 1 1003 ? 172.799 182.704 144.902 1.00 1.43   ? 1003 PHE A CG  1 
ATOM 6543 C CD1 . PHE A 1 1003 ? 173.863 183.263 145.586 1.00 2.88   ? 1003 PHE A CD1 1 
ATOM 6544 C CD2 . PHE A 1 1003 ? 172.373 183.302 143.730 1.00 1.80   ? 1003 PHE A CD2 1 
ATOM 6545 C CE1 . PHE A 1 1003 ? 174.487 184.396 145.113 1.00 3.73   ? 1003 PHE A CE1 1 
ATOM 6546 C CE2 . PHE A 1 1003 ? 172.994 184.436 143.252 1.00 5.97   ? 1003 PHE A CE2 1 
ATOM 6547 C CZ  . PHE A 1 1003 ? 174.051 184.984 143.945 1.00 6.81   ? 1003 PHE A CZ  1 
ATOM 6548 N N   . THR A 1 1004 ? 173.583 179.112 146.895 1.00 3.33   ? 1004 THR A N   1 
ATOM 6549 C CA  . THR A 1 1004 ? 174.557 178.377 147.684 1.00 3.51   ? 1004 THR A CA  1 
ATOM 6550 C C   . THR A 1 1004 ? 174.044 176.958 147.873 1.00 9.67   ? 1004 THR A C   1 
ATOM 6551 O O   . THR A 1 1004 ? 172.846 176.744 148.079 1.00 9.31   ? 1004 THR A O   1 
ATOM 6552 C CB  . THR A 1 1004 ? 174.809 179.037 149.042 1.00 8.02   ? 1004 THR A CB  1 
ATOM 6553 O OG1 . THR A 1 1004 ? 173.562 179.276 149.703 1.00 9.28   ? 1004 THR A OG1 1 
ATOM 6554 C CG2 . THR A 1 1004 ? 175.545 180.353 148.862 1.00 10.01  ? 1004 THR A CG2 1 
ATOM 6555 N N   . ARG A 1 1005 ? 174.951 175.992 147.791 1.00 10.88  ? 1005 ARG A N   1 
ATOM 6556 C CA  . ARG A 1 1005 ? 174.595 174.584 147.809 1.00 14.89  ? 1005 ARG A CA  1 
ATOM 6557 C C   . ARG A 1 1005 ? 174.885 173.974 149.173 1.00 19.18  ? 1005 ARG A C   1 
ATOM 6558 O O   . ARG A 1 1005 ? 175.791 174.409 149.889 1.00 18.57  ? 1005 ARG A O   1 
ATOM 6559 C CB  . ARG A 1 1005 ? 175.357 173.814 146.727 1.00 14.14  ? 1005 ARG A CB  1 
ATOM 6560 C CG  . ARG A 1 1005 ? 175.470 174.552 145.409 1.00 13.89  ? 1005 ARG A CG  1 
ATOM 6561 C CD  . ARG A 1 1005 ? 176.302 173.767 144.415 1.00 16.15  ? 1005 ARG A CD  1 
ATOM 6562 N NE  . ARG A 1 1005 ? 175.779 172.422 144.213 1.00 16.56  ? 1005 ARG A NE  1 
ATOM 6563 C CZ  . ARG A 1 1005 ? 176.062 171.659 143.167 1.00 20.02  ? 1005 ARG A CZ  1 
ATOM 6564 N NH1 . ARG A 1 1005 ? 176.863 172.080 142.203 1.00 19.19  ? 1005 ARG A NH1 1 
ATOM 6565 N NH2 . ARG A 1 1005 ? 175.528 170.444 143.087 1.00 16.18  ? 1005 ARG A NH2 1 
ATOM 6566 N N   . CYS A 1 1006 ? 174.100 172.960 149.524 1.00 26.16  ? 1006 CYS A N   1 
ATOM 6567 C CA  . CYS A 1 1006 ? 174.348 172.206 150.739 1.00 23.72  ? 1006 CYS A CA  1 
ATOM 6568 C C   . CYS A 1 1006 ? 175.569 171.308 150.564 1.00 28.61  ? 1006 CYS A C   1 
ATOM 6569 O O   . CYS A 1 1006 ? 176.069 171.093 149.458 1.00 36.98  ? 1006 CYS A O   1 
ATOM 6570 C CB  . CYS A 1 1006 ? 173.129 171.362 151.108 1.00 23.61  ? 1006 CYS A CB  1 
ATOM 6571 S SG  . CYS A 1 1006 ? 171.631 172.306 151.415 1.00 47.10  ? 1006 CYS A SG  1 
ATOM 6572 N N   . TRP A 1 1007 ? 176.052 170.781 151.682 1.00 28.04  ? 1007 TRP A N   1 
ATOM 6573 C CA  . TRP A 1 1007 ? 177.134 169.809 151.666 1.00 26.85  ? 1007 TRP A CA  1 
ATOM 6574 C C   . TRP A 1 1007 ? 176.621 168.377 151.631 1.00 31.08  ? 1007 TRP A C   1 
ATOM 6575 O O   . TRP A 1 1007 ? 177.424 167.441 151.686 1.00 35.79  ? 1007 TRP A O   1 
ATOM 6576 C CB  . TRP A 1 1007 ? 178.045 170.018 152.879 1.00 28.95  ? 1007 TRP A CB  1 
ATOM 6577 C CG  . TRP A 1 1007 ? 178.898 171.247 152.762 1.00 31.07  ? 1007 TRP A CG  1 
ATOM 6578 C CD1 . TRP A 1 1007 ? 178.734 172.275 151.880 1.00 30.78  ? 1007 TRP A CD1 1 
ATOM 6579 C CD2 . TRP A 1 1007 ? 180.044 171.578 153.554 1.00 32.26  ? 1007 TRP A CD2 1 
ATOM 6580 N NE1 . TRP A 1 1007 ? 179.707 173.224 152.072 1.00 32.74  ? 1007 TRP A NE1 1 
ATOM 6581 C CE2 . TRP A 1 1007 ? 180.524 172.820 153.095 1.00 32.23  ? 1007 TRP A CE2 1 
ATOM 6582 C CE3 . TRP A 1 1007 ? 180.710 170.946 154.606 1.00 29.87  ? 1007 TRP A CE3 1 
ATOM 6583 C CZ2 . TRP A 1 1007 ? 181.639 173.440 153.651 1.00 30.72  ? 1007 TRP A CZ2 1 
ATOM 6584 C CZ3 . TRP A 1 1007 ? 181.817 171.563 155.156 1.00 32.98  ? 1007 TRP A CZ3 1 
ATOM 6585 C CH2 . TRP A 1 1007 ? 182.269 172.797 154.678 1.00 32.34  ? 1007 TRP A CH2 1 
ATOM 6586 N N   . ASN A 1 1008 ? 175.309 168.190 151.542 1.00 27.38  ? 1008 ASN A N   1 
ATOM 6587 C CA  . ASN A 1 1008 ? 174.696 166.868 151.431 1.00 25.28  ? 1008 ASN A CA  1 
ATOM 6588 C C   . ASN A 1 1008 ? 173.901 166.791 150.139 1.00 29.33  ? 1008 ASN A C   1 
ATOM 6589 O O   . ASN A 1 1008 ? 172.916 167.537 149.979 1.00 32.31  ? 1008 ASN A O   1 
ATOM 6590 C CB  . ASN A 1 1008 ? 173.789 166.592 152.628 1.00 26.39  ? 1008 ASN A CB  1 
ATOM 6591 C CG  . ASN A 1 1008 ? 173.319 165.152 152.682 1.00 30.84  ? 1008 ASN A CG  1 
ATOM 6592 O OD1 . ASN A 1 1008 ? 174.050 164.235 152.311 1.00 30.23  ? 1008 ASN A OD1 1 
ATOM 6593 N ND2 . ASN A 1 1008 ? 172.092 164.947 153.145 1.00 31.93  ? 1008 ASN A ND2 1 
ATOM 6594 N N   . PRO A 1 1009 ? 174.281 165.933 149.189 1.00 27.81  ? 1009 PRO A N   1 
ATOM 6595 C CA  . PRO A 1 1009 ? 173.492 165.824 147.951 1.00 21.63  ? 1009 PRO A CA  1 
ATOM 6596 C C   . PRO A 1 1009 ? 172.055 165.402 148.189 1.00 25.36  ? 1009 PRO A C   1 
ATOM 6597 O O   . PRO A 1 1009 ? 171.169 165.817 147.435 1.00 25.70  ? 1009 PRO A O   1 
ATOM 6598 C CB  . PRO A 1 1009 ? 174.247 164.775 147.122 1.00 20.83  ? 1009 PRO A CB  1 
ATOM 6599 C CG  . PRO A 1 1009 ? 175.325 164.251 147.975 1.00 24.31  ? 1009 PRO A CG  1 
ATOM 6600 C CD  . PRO A 1 1009 ? 175.506 165.121 149.164 1.00 28.01  ? 1009 PRO A CD  1 
ATOM 6601 N N   . ALA A 1 1010 ? 171.796 164.576 149.206 1.00 27.37  ? 1010 ALA A N   1 
ATOM 6602 C CA  . ALA A 1 1010 ? 170.427 164.154 149.484 1.00 25.49  ? 1010 ALA A CA  1 
ATOM 6603 C C   . ALA A 1 1010 ? 169.560 165.333 149.907 1.00 23.20  ? 1010 ALA A C   1 
ATOM 6604 O O   . ALA A 1 1010 ? 168.424 165.475 149.444 1.00 26.87  ? 1010 ALA A O   1 
ATOM 6605 C CB  . ALA A 1 1010 ? 170.421 163.068 150.558 1.00 25.08  ? 1010 ALA A CB  1 
ATOM 6606 N N   . LYS A 1 1011 ? 170.084 166.195 150.781 1.00 23.65  ? 1011 LYS A N   1 
ATOM 6607 C CA  . LYS A 1 1011 ? 169.339 167.377 151.205 1.00 27.59  ? 1011 LYS A CA  1 
ATOM 6608 C C   . LYS A 1 1011 ? 169.106 168.331 150.040 1.00 29.74  ? 1011 LYS A C   1 
ATOM 6609 O O   . LYS A 1 1011 ? 168.032 168.931 149.918 1.00 30.34  ? 1011 LYS A O   1 
ATOM 6610 C CB  . LYS A 1 1011 ? 170.093 168.078 152.334 1.00 29.75  ? 1011 LYS A CB  1 
ATOM 6611 C CG  . LYS A 1 1011 ? 169.377 169.267 152.945 1.00 30.07  ? 1011 LYS A CG  1 
ATOM 6612 C CD  . LYS A 1 1011 ? 170.182 169.827 154.106 1.00 29.80  ? 1011 LYS A CD  1 
ATOM 6613 C CE  . LYS A 1 1011 ? 169.500 171.024 154.738 1.00 26.90  ? 1011 LYS A CE  1 
ATOM 6614 N NZ  . LYS A 1 1011 ? 170.300 171.562 155.871 1.00 31.02  ? 1011 LYS A NZ  1 
ATOM 6615 N N   . GLU A 1 1012 ? 170.108 168.485 149.175 1.00 28.55  ? 1012 GLU A N   1 
ATOM 6616 C CA  . GLU A 1 1012 ? 169.980 169.370 148.023 1.00 18.61  ? 1012 GLU A CA  1 
ATOM 6617 C C   . GLU A 1 1012 ? 168.955 168.839 147.027 1.00 18.09  ? 1012 GLU A C   1 
ATOM 6618 O O   . GLU A 1 1012 ? 168.157 169.607 146.476 1.00 25.42  ? 1012 GLU A O   1 
ATOM 6619 C CB  . GLU A 1 1012 ? 171.352 169.540 147.378 1.00 20.19  ? 1012 GLU A CB  1 
ATOM 6620 C CG  . GLU A 1 1012 ? 171.430 170.494 146.215 1.00 18.03  ? 1012 GLU A CG  1 
ATOM 6621 C CD  . GLU A 1 1012 ? 172.844 170.609 145.707 1.00 24.78  ? 1012 GLU A CD  1 
ATOM 6622 O OE1 . GLU A 1 1012 ? 173.698 169.922 146.267 1.00 36.83  ? 1012 GLU A OE1 1 
ATOM 6623 O OE2 . GLU A 1 1012 ? 173.101 171.390 144.778 1.00 25.18  ? 1012 GLU A OE2 1 
ATOM 6624 N N   . ASP A 1 1013 ? 168.953 167.525 146.791 1.00 21.89  ? 1013 ASP A N   1 
ATOM 6625 C CA  . ASP A 1 1013 ? 167.926 166.920 145.950 1.00 20.97  ? 1013 ASP A CA  1 
ATOM 6626 C C   . ASP A 1 1013 ? 166.550 167.046 146.588 1.00 23.71  ? 1013 ASP A C   1 
ATOM 6627 O O   . ASP A 1 1013 ? 165.553 167.230 145.887 1.00 22.48  ? 1013 ASP A O   1 
ATOM 6628 C CB  . ASP A 1 1013 ? 168.254 165.452 145.681 1.00 24.36  ? 1013 ASP A CB  1 
ATOM 6629 C CG  . ASP A 1 1013 ? 169.553 165.271 144.926 1.00 31.20  ? 1013 ASP A CG  1 
ATOM 6630 O OD1 . ASP A 1 1013 ? 170.138 166.284 144.490 1.00 33.11  ? 1013 ASP A OD1 1 
ATOM 6631 O OD2 . ASP A 1 1013 ? 169.991 164.112 144.768 1.00 28.87  ? 1013 ASP A OD2 1 
ATOM 6632 N N   . GLN A 1 1014 ? 166.475 166.936 147.915 1.00 23.70  ? 1014 GLN A N   1 
ATOM 6633 C CA  . GLN A 1 1014 ? 165.211 167.143 148.613 1.00 21.32  ? 1014 GLN A CA  1 
ATOM 6634 C C   . GLN A 1 1014 ? 164.691 168.558 148.401 1.00 27.42  ? 1014 GLN A C   1 
ATOM 6635 O O   . GLN A 1 1014 ? 163.494 168.762 148.170 1.00 30.79  ? 1014 GLN A O   1 
ATOM 6636 C CB  . GLN A 1 1014 ? 165.399 166.853 150.102 1.00 24.64  ? 1014 GLN A CB  1 
ATOM 6637 C CG  . GLN A 1 1014 ? 164.160 167.030 150.954 1.00 28.22  ? 1014 GLN A CG  1 
ATOM 6638 C CD  . GLN A 1 1014 ? 164.498 167.228 152.419 1.00 35.09  ? 1014 GLN A CD  1 
ATOM 6639 O OE1 . GLN A 1 1014 ? 163.908 168.069 153.097 1.00 34.84  ? 1014 GLN A OE1 1 
ATOM 6640 N NE2 . GLN A 1 1014 ? 165.460 166.457 152.913 1.00 32.76  ? 1014 GLN A NE2 1 
ATOM 6641 N N   . ALA A 1 1015 ? 165.580 169.549 148.485 1.00 29.20  ? 1015 ALA A N   1 
ATOM 6642 C CA  . ALA A 1 1015 ? 165.182 170.930 148.226 1.00 17.66  ? 1015 ALA A CA  1 
ATOM 6643 C C   . ALA A 1 1015 ? 164.743 171.115 146.779 1.00 19.14  ? 1015 ALA A C   1 
ATOM 6644 O O   . ALA A 1 1015 ? 163.764 171.819 146.505 1.00 22.41  ? 1015 ALA A O   1 
ATOM 6645 C CB  . ALA A 1 1015 ? 166.329 171.880 148.566 1.00 21.94  ? 1015 ALA A CB  1 
ATOM 6646 N N   . THR A 1 1016 ? 165.458 170.493 145.839 1.00 18.98  ? 1016 THR A N   1 
ATOM 6647 C CA  . THR A 1 1016 ? 165.070 170.576 144.434 1.00 20.29  ? 1016 THR A CA  1 
ATOM 6648 C C   . THR A 1 1016 ? 163.700 169.951 144.204 1.00 24.26  ? 1016 THR A C   1 
ATOM 6649 O O   . THR A 1 1016 ? 162.883 170.486 143.445 1.00 28.40  ? 1016 THR A O   1 
ATOM 6650 C CB  . THR A 1 1016 ? 166.113 169.890 143.553 1.00 23.08  ? 1016 THR A CB  1 
ATOM 6651 O OG1 . THR A 1 1016 ? 167.367 170.566 143.678 1.00 18.70  ? 1016 THR A OG1 1 
ATOM 6652 C CG2 . THR A 1 1016 ? 165.680 169.918 142.097 1.00 18.87  ? 1016 THR A CG2 1 
ATOM 6653 N N   . ASP A 1 1017 ? 163.428 168.822 144.857 1.00 28.35  ? 1017 ASP A N   1 
ATOM 6654 C CA  . ASP A 1 1017 ? 162.157 168.132 144.697 1.00 24.98  ? 1017 ASP A CA  1 
ATOM 6655 C C   . ASP A 1 1017 ? 161.093 168.778 145.570 1.00 28.31  ? 1017 ASP A C   1 
ATOM 6656 O O   . ASP A 1 1017 ? 160.389 168.100 146.324 1.00 34.96  ? 1017 ASP A O   1 
ATOM 6657 C CB  . ASP A 1 1017 ? 162.299 166.647 145.034 1.00 28.66  ? 1017 ASP A CB  1 
ATOM 6658 C CG  . ASP A 1 1017 ? 163.467 165.997 144.320 1.00 38.06  ? 1017 ASP A CG  1 
ATOM 6659 O OD1 . ASP A 1 1017 ? 163.942 166.563 143.313 1.00 36.39  ? 1017 ASP A OD1 1 
ATOM 6660 O OD2 . ASP A 1 1017 ? 163.912 164.918 144.765 1.00 41.74  ? 1017 ASP A OD2 1 
ATOM 6661 N N   . ARG A 1 1018 ? 160.991 170.101 145.476 1.00 31.56  ? 1018 ARG A N   1 
ATOM 6662 C CA  . ARG A 1 1018 ? 159.841 170.850 145.948 1.00 32.09  ? 1018 ARG A CA  1 
ATOM 6663 C C   . ARG A 1 1018 ? 159.077 171.471 144.794 1.00 33.06  ? 1018 ARG A C   1 
ATOM 6664 O O   . ARG A 1 1018 ? 157.876 171.726 144.926 1.00 38.76  ? 1018 ARG A O   1 
ATOM 6665 C CB  . ARG A 1 1018 ? 160.283 171.949 146.927 1.00 32.16  ? 1018 ARG A CB  1 
ATOM 6666 C CG  . ARG A 1 1018 ? 160.867 171.439 148.240 1.00 32.04  ? 1018 ARG A CG  1 
ATOM 6667 C CD  . ARG A 1 1018 ? 161.300 172.597 149.129 1.00 31.73  ? 1018 ARG A CD  1 
ATOM 6668 N NE  . ARG A 1 1018 ? 160.169 173.396 149.585 1.00 34.46  ? 1018 ARG A NE  1 
ATOM 6669 C CZ  . ARG A 1 1018 ? 160.280 174.547 150.234 1.00 36.48  ? 1018 ARG A CZ  1 
ATOM 6670 N NH1 . ARG A 1 1018 ? 161.462 175.074 150.510 1.00 34.70  ? 1018 ARG A NH1 1 
ATOM 6671 N NH2 . ARG A 1 1018 ? 159.178 175.187 150.614 1.00 36.57  ? 1018 ARG A NH2 1 
ATOM 6672 N N   . ALA A 1 1019 ? 159.749 171.699 143.668 1.00 31.76  ? 1019 ALA A N   1 
ATOM 6673 C CA  . ALA A 1 1019 ? 159.145 172.053 142.393 1.00 31.93  ? 1019 ALA A CA  1 
ATOM 6674 C C   . ALA A 1 1019 ? 159.103 170.888 141.420 1.00 35.54  ? 1019 ALA A C   1 
ATOM 6675 O O   . ALA A 1 1019 ? 158.122 170.732 140.692 1.00 42.67  ? 1019 ALA A O   1 
ATOM 6676 C CB  . ALA A 1 1019 ? 159.913 173.215 141.758 1.00 33.52  ? 1019 ALA A CB  1 
ATOM 6677 N N   . TYR A 1 1020 ? 160.150 170.062 141.402 1.00 35.69  ? 1020 TYR A N   1 
ATOM 6678 C CA  . TYR A 1 1020 ? 160.209 168.863 140.567 1.00 36.87  ? 1020 TYR A CA  1 
ATOM 6679 C C   . TYR A 1 1020 ? 159.514 167.716 141.295 1.00 38.31  ? 1020 TYR A C   1 
ATOM 6680 O O   . TYR A 1 1020 ? 160.138 166.770 141.780 1.00 41.21  ? 1020 TYR A O   1 
ATOM 6681 C CB  . TYR A 1 1020 ? 161.654 168.508 140.242 1.00 36.89  ? 1020 TYR A CB  1 
ATOM 6682 C CG  . TYR A 1 1020 ? 161.800 167.254 139.408 1.00 39.61  ? 1020 TYR A CG  1 
ATOM 6683 C CD1 . TYR A 1 1020 ? 161.280 167.192 138.125 1.00 40.84  ? 1020 TYR A CD1 1 
ATOM 6684 C CD2 . TYR A 1 1020 ? 162.457 166.134 139.904 1.00 40.14  ? 1020 TYR A CD2 1 
ATOM 6685 C CE1 . TYR A 1 1020 ? 161.407 166.055 137.356 1.00 44.24  ? 1020 TYR A CE1 1 
ATOM 6686 C CE2 . TYR A 1 1020 ? 162.591 164.990 139.140 1.00 37.14  ? 1020 TYR A CE2 1 
ATOM 6687 C CZ  . TYR A 1 1020 ? 162.063 164.958 137.867 1.00 40.95  ? 1020 TYR A CZ  1 
ATOM 6688 O OH  . TYR A 1 1020 ? 162.191 163.825 137.097 1.00 43.80  ? 1020 TYR A OH  1 
ATOM 6689 N N   . ARG A 1 1021 ? 158.193 167.800 141.375 1.00 45.38  ? 1021 ARG A N   1 
ATOM 6690 C CA  . ARG A 1 1021 ? 157.407 166.738 141.988 1.00 46.39  ? 1021 ARG A CA  1 
ATOM 6691 C C   . ARG A 1 1021 ? 156.312 166.274 141.030 1.00 53.05  ? 1021 ARG A C   1 
ATOM 6692 O O   . ARG A 1 1021 ? 156.226 166.718 139.882 1.00 55.63  ? 1021 ARG A O   1 
ATOM 6693 C CB  . ARG A 1 1021 ? 156.804 167.188 143.320 1.00 45.32  ? 1021 ARG A CB  1 
ATOM 6694 C CG  . ARG A 1 1021 ? 157.795 167.441 144.431 1.00 49.05  ? 1021 ARG A CG  1 
ATOM 6695 C CD  . ARG A 1 1021 ? 157.054 167.875 145.683 1.00 44.81  ? 1021 ARG A CD  1 
ATOM 6696 N NE  . ARG A 1 1021 ? 157.978 168.154 146.772 1.00 47.84  ? 1021 ARG A NE  1 
ATOM 6697 C CZ  . ARG A 1 1021 ? 157.625 168.603 147.969 1.00 48.80  ? 1021 ARG A CZ  1 
ATOM 6698 N NH1 . ARG A 1 1021 ? 156.355 168.756 148.307 1.00 51.07  ? 1021 ARG A NH1 1 
ATOM 6699 N NH2 . ARG A 1 1021 ? 158.574 168.910 148.849 1.00 47.41  ? 1021 ARG A NH2 1 
ATOM 6700 N N   . ILE A 1 1022 ? 155.461 165.373 141.529 1.00 55.03  ? 1022 ILE A N   1 
ATOM 6701 C CA  . ILE A 1 1022 ? 154.461 164.719 140.695 1.00 55.02  ? 1022 ILE A CA  1 
ATOM 6702 C C   . ILE A 1 1022 ? 153.412 165.699 140.186 1.00 56.81  ? 1022 ILE A C   1 
ATOM 6703 O O   . ILE A 1 1022 ? 152.813 165.467 139.129 1.00 54.81  ? 1022 ILE A O   1 
ATOM 6704 C CB  . ILE A 1 1022 ? 153.810 163.557 141.474 1.00 55.69  ? 1022 ILE A CB  1 
ATOM 6705 C CG1 . ILE A 1 1022 ? 153.006 162.665 140.532 1.00 56.15  ? 1022 ILE A CG1 1 
ATOM 6706 C CG2 . ILE A 1 1022 ? 152.939 164.077 142.610 1.00 54.43  ? 1022 ILE A CG2 1 
ATOM 6707 C CD1 . ILE A 1 1022 ? 153.878 161.949 139.536 1.00 53.97  ? 1022 ILE A CD1 1 
ATOM 6708 N N   . GLY A 1 1023 ? 153.174 166.790 140.906 1.00 53.12  ? 1023 GLY A N   1 
ATOM 6709 C CA  . GLY A 1 1023 ? 152.234 167.808 140.495 1.00 53.14  ? 1023 GLY A CA  1 
ATOM 6710 C C   . GLY A 1 1023 ? 152.802 168.869 139.581 1.00 53.99  ? 1023 GLY A C   1 
ATOM 6711 O O   . GLY A 1 1023 ? 152.092 169.821 139.241 1.00 53.30  ? 1023 GLY A O   1 
ATOM 6712 N N   . GLN A 1 1024 ? 154.061 168.738 139.171 1.00 47.96  ? 1024 GLN A N   1 
ATOM 6713 C CA  . GLN A 1 1024 ? 154.688 169.718 138.295 1.00 46.27  ? 1024 GLN A CA  1 
ATOM 6714 C C   . GLN A 1 1024 ? 154.245 169.500 136.854 1.00 46.79  ? 1024 GLN A C   1 
ATOM 6715 O O   . GLN A 1 1024 ? 154.249 168.369 136.357 1.00 46.22  ? 1024 GLN A O   1 
ATOM 6716 C CB  . GLN A 1 1024 ? 156.209 169.625 138.398 1.00 40.44  ? 1024 GLN A CB  1 
ATOM 6717 C CG  . GLN A 1 1024 ? 156.956 170.659 137.573 1.00 42.10  ? 1024 GLN A CG  1 
ATOM 6718 C CD  . GLN A 1 1024 ? 156.659 172.080 138.004 1.00 42.88  ? 1024 GLN A CD  1 
ATOM 6719 O OE1 . GLN A 1 1024 ? 155.921 172.803 137.335 1.00 42.83  ? 1024 GLN A OE1 1 
ATOM 6720 N NE2 . GLN A 1 1024 ? 157.236 172.491 139.126 1.00 44.03  ? 1024 GLN A NE2 1 
ATOM 6721 N N   . THR A 1 1025 ? 153.866 170.586 136.183 1.00 45.37  ? 1025 THR A N   1 
ATOM 6722 C CA  . THR A 1 1025 ? 153.458 170.539 134.784 1.00 46.25  ? 1025 THR A CA  1 
ATOM 6723 C C   . THR A 1 1025 ? 154.584 170.932 133.835 1.00 46.61  ? 1025 THR A C   1 
ATOM 6724 O O   . THR A 1 1025 ? 154.929 170.166 132.930 1.00 49.28  ? 1025 THR A O   1 
ATOM 6725 C CB  . THR A 1 1025 ? 152.248 171.452 134.552 1.00 46.31  ? 1025 THR A CB  1 
ATOM 6726 O OG1 . THR A 1 1025 ? 152.662 172.823 134.612 1.00 46.09  ? 1025 THR A OG1 1 
ATOM 6727 C CG2 . THR A 1 1025 ? 151.182 171.203 135.607 1.00 45.92  ? 1025 THR A CG2 1 
ATOM 6728 N N   . LYS A 1 1026 ? 155.165 172.113 134.026 1.00 37.01  ? 1026 LYS A N   1 
ATOM 6729 C CA  . LYS A 1 1026 ? 156.206 172.602 133.139 1.00 36.15  ? 1026 LYS A CA  1 
ATOM 6730 C C   . LYS A 1 1026 ? 157.551 171.968 133.484 1.00 36.15  ? 1026 LYS A C   1 
ATOM 6731 O O   . LYS A 1 1026 ? 157.738 171.383 134.554 1.00 39.59  ? 1026 LYS A O   1 
ATOM 6732 C CB  . LYS A 1 1026 ? 156.297 174.126 133.219 1.00 35.85  ? 1026 LYS A CB  1 
ATOM 6733 C CG  . LYS A 1 1026 ? 155.068 174.830 132.666 1.00 38.53  ? 1026 LYS A CG  1 
ATOM 6734 C CD  . LYS A 1 1026 ? 155.250 176.335 132.609 1.00 35.15  ? 1026 LYS A CD  1 
ATOM 6735 C CE  . LYS A 1 1026 ? 155.175 176.954 133.987 1.00 35.66  ? 1026 LYS A CE  1 
ATOM 6736 N NZ  . LYS A 1 1026 ? 155.245 178.436 133.929 1.00 39.28  ? 1026 LYS A NZ  1 
ATOM 6737 N N   . ASN A 1 1027 ? 158.491 172.085 132.550 1.00 30.98  ? 1027 ASN A N   1 
ATOM 6738 C CA  . ASN A 1 1027 ? 159.823 171.531 132.752 1.00 26.15  ? 1027 ASN A CA  1 
ATOM 6739 C C   . ASN A 1 1027 ? 160.540 172.268 133.874 1.00 24.92  ? 1027 ASN A C   1 
ATOM 6740 O O   . ASN A 1 1027 ? 160.436 173.488 134.001 1.00 29.59  ? 1027 ASN A O   1 
ATOM 6741 C CB  . ASN A 1 1027 ? 160.637 171.627 131.462 1.00 28.55  ? 1027 ASN A CB  1 
ATOM 6742 C CG  . ASN A 1 1027 ? 160.202 170.614 130.423 1.00 37.10  ? 1027 ASN A CG  1 
ATOM 6743 O OD1 . ASN A 1 1027 ? 159.221 169.895 130.611 1.00 39.87  ? 1027 ASN A OD1 1 
ATOM 6744 N ND2 . ASN A 1 1027 ? 160.928 170.559 129.313 1.00 34.00  ? 1027 ASN A ND2 1 
ATOM 6745 N N   . VAL A 1 1028 ? 161.278 171.522 134.688 1.00 21.12  ? 1028 VAL A N   1 
ATOM 6746 C CA  . VAL A 1 1028 ? 161.997 172.080 135.827 1.00 20.07  ? 1028 VAL A CA  1 
ATOM 6747 C C   . VAL A 1 1028 ? 163.424 172.382 135.395 1.00 18.62  ? 1028 VAL A C   1 
ATOM 6748 O O   . VAL A 1 1028 ? 164.166 171.477 134.996 1.00 21.00  ? 1028 VAL A O   1 
ATOM 6749 C CB  . VAL A 1 1028 ? 161.975 171.126 137.030 1.00 19.06  ? 1028 VAL A CB  1 
ATOM 6750 C CG1 . VAL A 1 1028 ? 162.513 171.822 138.268 1.00 20.00  ? 1028 VAL A CG1 1 
ATOM 6751 C CG2 . VAL A 1 1028 ? 160.567 170.625 137.274 1.00 23.59  ? 1028 VAL A CG2 1 
ATOM 6752 N N   . TYR A 1 1029 ? 163.805 173.652 135.473 1.00 14.80  ? 1029 TYR A N   1 
ATOM 6753 C CA  . TYR A 1 1029 ? 165.164 174.089 135.187 1.00 5.04   ? 1029 TYR A CA  1 
ATOM 6754 C C   . TYR A 1 1029 ? 165.895 174.272 136.509 1.00 7.86   ? 1029 TYR A C   1 
ATOM 6755 O O   . TYR A 1 1029 ? 165.485 175.089 137.340 1.00 14.94  ? 1029 TYR A O   1 
ATOM 6756 C CB  . TYR A 1 1029 ? 165.164 175.388 134.383 1.00 3.21   ? 1029 TYR A CB  1 
ATOM 6757 C CG  . TYR A 1 1029 ? 164.574 175.247 132.999 1.00 11.26  ? 1029 TYR A CG  1 
ATOM 6758 C CD1 . TYR A 1 1029 ? 163.241 175.551 132.758 1.00 13.55  ? 1029 TYR A CD1 1 
ATOM 6759 C CD2 . TYR A 1 1029 ? 165.349 174.811 131.935 1.00 11.84  ? 1029 TYR A CD2 1 
ATOM 6760 C CE1 . TYR A 1 1029 ? 162.698 175.424 131.495 1.00 11.35  ? 1029 TYR A CE1 1 
ATOM 6761 C CE2 . TYR A 1 1029 ? 164.815 174.682 130.669 1.00 12.97  ? 1029 TYR A CE2 1 
ATOM 6762 C CZ  . TYR A 1 1029 ? 163.490 174.988 130.454 1.00 14.38  ? 1029 TYR A CZ  1 
ATOM 6763 O OH  . TYR A 1 1029 ? 162.956 174.860 129.193 1.00 19.35  ? 1029 TYR A OH  1 
ATOM 6764 N N   . VAL A 1 1030 ? 166.969 173.514 136.704 1.00 8.69   ? 1030 VAL A N   1 
ATOM 6765 C CA  . VAL A 1 1030 ? 167.728 173.528 137.947 1.00 6.37   ? 1030 VAL A CA  1 
ATOM 6766 C C   . VAL A 1 1030 ? 169.073 174.181 137.667 1.00 9.10   ? 1030 VAL A C   1 
ATOM 6767 O O   . VAL A 1 1030 ? 169.823 173.728 136.795 1.00 11.88  ? 1030 VAL A O   1 
ATOM 6768 C CB  . VAL A 1 1030 ? 167.907 172.115 138.520 1.00 4.28   ? 1030 VAL A CB  1 
ATOM 6769 C CG1 . VAL A 1 1030 ? 168.742 172.163 139.784 1.00 8.37   ? 1030 VAL A CG1 1 
ATOM 6770 C CG2 . VAL A 1 1030 ? 166.553 171.481 138.790 1.00 7.84   ? 1030 VAL A CG2 1 
ATOM 6771 N N   . TYR A 1 1031 ? 169.376 175.242 138.407 1.00 11.39  ? 1031 TYR A N   1 
ATOM 6772 C CA  . TYR A 1 1031 ? 170.593 176.016 138.220 1.00 4.20   ? 1031 TYR A CA  1 
ATOM 6773 C C   . TYR A 1 1031 ? 171.535 175.766 139.387 1.00 4.07   ? 1031 TYR A C   1 
ATOM 6774 O O   . TYR A 1 1031 ? 171.112 175.786 140.547 1.00 1.43   ? 1031 TYR A O   1 
ATOM 6775 C CB  . TYR A 1 1031 ? 170.285 177.510 138.105 1.00 5.14   ? 1031 TYR A CB  1 
ATOM 6776 C CG  . TYR A 1 1031 ? 169.331 177.871 136.988 1.00 0.78   ? 1031 TYR A CG  1 
ATOM 6777 C CD1 . TYR A 1 1031 ? 167.961 177.718 137.142 1.00 0.00   ? 1031 TYR A CD1 1 
ATOM 6778 C CD2 . TYR A 1 1031 ? 169.801 178.375 135.786 1.00 0.00   ? 1031 TYR A CD2 1 
ATOM 6779 C CE1 . TYR A 1 1031 ? 167.089 178.049 136.128 1.00 0.92   ? 1031 TYR A CE1 1 
ATOM 6780 C CE2 . TYR A 1 1031 ? 168.936 178.709 134.767 1.00 0.98   ? 1031 TYR A CE2 1 
ATOM 6781 C CZ  . TYR A 1 1031 ? 167.582 178.545 134.943 1.00 0.89   ? 1031 TYR A CZ  1 
ATOM 6782 O OH  . TYR A 1 1031 ? 166.717 178.878 133.928 1.00 4.08   ? 1031 TYR A OH  1 
ATOM 6783 N N   . TYR A 1 1032 ? 172.806 175.534 139.076 1.00 10.85  ? 1032 TYR A N   1 
ATOM 6784 C CA  . TYR A 1 1032 ? 173.877 175.375 140.068 1.00 4.51   ? 1032 TYR A CA  1 
ATOM 6785 C C   . TYR A 1 1032 ? 174.986 176.334 139.724 1.00 9.09   ? 1032 TYR A C   1 
ATOM 6786 O O   . TYR A 1 1032 ? 176.029 175.936 139.183 1.00 21.16  ? 1032 TYR A O   1 
ATOM 6787 C CB  . TYR A 1 1032 ? 174.386 173.930 140.095 1.00 7.11   ? 1032 TYR A CB  1 
ATOM 6788 C CG  . TYR A 1 1032 ? 173.391 172.907 140.575 1.00 6.32   ? 1032 TYR A CG  1 
ATOM 6789 C CD1 . TYR A 1 1032 ? 172.810 173.016 141.826 1.00 8.34   ? 1032 TYR A CD1 1 
ATOM 6790 C CD2 . TYR A 1 1032 ? 173.047 171.821 139.785 1.00 4.30   ? 1032 TYR A CD2 1 
ATOM 6791 C CE1 . TYR A 1 1032 ? 171.899 172.086 142.266 1.00 15.25  ? 1032 TYR A CE1 1 
ATOM 6792 C CE2 . TYR A 1 1032 ? 172.141 170.881 140.224 1.00 3.04   ? 1032 TYR A CE2 1 
ATOM 6793 C CZ  . TYR A 1 1032 ? 171.572 171.017 141.467 1.00 11.47  ? 1032 TYR A CZ  1 
ATOM 6794 O OH  . TYR A 1 1032 ? 170.665 170.085 141.915 1.00 16.41  ? 1032 TYR A OH  1 
ATOM 6795 N N   . PRO A 1 1033 ? 174.817 177.592 139.999 1.00 9.08   ? 1033 PRO A N   1 
ATOM 6796 C CA  . PRO A 1 1033 ? 175.779 178.642 139.611 1.00 7.86   ? 1033 PRO A CA  1 
ATOM 6797 C C   . PRO A 1 1033 ? 177.103 178.380 140.271 1.00 11.28  ? 1033 PRO A C   1 
ATOM 6798 O O   . PRO A 1 1033 ? 177.245 178.511 141.488 1.00 22.28  ? 1033 PRO A O   1 
ATOM 6799 C CB  . PRO A 1 1033 ? 175.116 179.928 140.154 1.00 5.58   ? 1033 PRO A CB  1 
ATOM 6800 C CG  . PRO A 1 1033 ? 173.802 179.562 140.620 1.00 0.00   ? 1033 PRO A CG  1 
ATOM 6801 C CD  . PRO A 1 1033 ? 173.592 178.119 140.699 1.00 7.15   ? 1033 PRO A CD  1 
ATOM 6802 N N   . THR A 1 1034 ? 178.079 178.015 139.463 1.00 4.93   ? 1034 THR A N   1 
ATOM 6803 C CA  . THR A 1 1034 ? 179.406 177.689 139.957 1.00 7.60   ? 1034 THR A CA  1 
ATOM 6804 C C   . THR A 1 1034 ? 180.402 178.674 139.370 1.00 8.57   ? 1034 THR A C   1 
ATOM 6805 O O   . THR A 1 1034 ? 180.509 178.801 138.147 1.00 20.60  ? 1034 THR A O   1 
ATOM 6806 C CB  . THR A 1 1034 ? 179.795 176.255 139.596 1.00 17.99  ? 1034 THR A CB  1 
ATOM 6807 O OG1 . THR A 1 1034 ? 178.668 175.393 139.790 1.00 21.13  ? 1034 THR A OG1 1 
ATOM 6808 C CG2 . THR A 1 1034 ? 180.931 175.781 140.474 1.00 19.03  ? 1034 THR A CG2 1 
ATOM 6809 N N   . VAL A 1 1035 ? 181.124 179.368 140.241 1.00 9.33   ? 1035 VAL A N   1 
ATOM 6810 C CA  . VAL A 1 1035 ? 182.120 180.337 139.800 1.00 14.84  ? 1035 VAL A CA  1 
ATOM 6811 C C   . VAL A 1 1035 ? 183.434 179.602 139.569 1.00 21.30  ? 1035 VAL A C   1 
ATOM 6812 O O   . VAL A 1 1035 ? 184.019 179.044 140.503 1.00 24.03  ? 1035 VAL A O   1 
ATOM 6813 C CB  . VAL A 1 1035 ? 182.280 181.467 140.825 1.00 14.89  ? 1035 VAL A CB  1 
ATOM 6814 C CG1 . VAL A 1 1035 ? 183.375 182.397 140.410 1.00 23.47  ? 1035 VAL A CG1 1 
ATOM 6815 C CG2 . VAL A 1 1035 ? 180.994 182.237 140.950 1.00 14.84  ? 1035 VAL A CG2 1 
ATOM 6816 N N   . ARG A 1 1036 ? 183.895 179.595 138.324 1.00 20.37  ? 1036 ARG A N   1 
ATOM 6817 C CA  . ARG A 1 1036 ? 185.073 178.853 137.902 1.00 15.05  ? 1036 ARG A CA  1 
ATOM 6818 C C   . ARG A 1 1036 ? 186.239 179.807 137.680 1.00 22.22  ? 1036 ARG A C   1 
ATOM 6819 O O   . ARG A 1 1036 ? 186.059 181.009 137.473 1.00 28.02  ? 1036 ARG A O   1 
ATOM 6820 C CB  . ARG A 1 1036 ? 184.793 178.080 136.608 1.00 21.66  ? 1036 ARG A CB  1 
ATOM 6821 C CG  . ARG A 1 1036 ? 183.677 177.047 136.683 1.00 20.22  ? 1036 ARG A CG  1 
ATOM 6822 C CD  . ARG A 1 1036 ? 184.045 175.864 137.568 1.00 22.13  ? 1036 ARG A CD  1 
ATOM 6823 N NE  . ARG A 1 1036 ? 182.976 174.872 137.662 1.00 24.51  ? 1036 ARG A NE  1 
ATOM 6824 C CZ  . ARG A 1 1036 ? 182.818 173.827 136.858 1.00 26.88  ? 1036 ARG A CZ  1 
ATOM 6825 N NH1 . ARG A 1 1036 ? 183.706 173.527 135.925 1.00 27.06  ? 1036 ARG A NH1 1 
ATOM 6826 N NH2 . ARG A 1 1036 ? 181.750 173.049 137.012 1.00 24.75  ? 1036 ARG A NH2 1 
ATOM 6827 N N   . ASP A 1 1037 ? 187.448 179.251 137.699 1.00 30.31  ? 1037 ASP A N   1 
ATOM 6828 C CA  . ASP A 1 1037 ? 188.643 180.018 137.383 1.00 34.73  ? 1037 ASP A CA  1 
ATOM 6829 C C   . ASP A 1 1037 ? 189.629 179.120 136.655 1.00 40.52  ? 1037 ASP A C   1 
ATOM 6830 O O   . ASP A 1 1037 ? 189.742 177.931 136.965 1.00 39.10  ? 1037 ASP A O   1 
ATOM 6831 C CB  . ASP A 1 1037 ? 189.302 180.605 138.633 1.00 34.27  ? 1037 ASP A CB  1 
ATOM 6832 C CG  . ASP A 1 1037 ? 190.205 181.780 138.313 1.00 38.19  ? 1037 ASP A CG  1 
ATOM 6833 O OD1 . ASP A 1 1037 ? 189.696 182.917 138.237 1.00 37.25  ? 1037 ASP A OD1 1 
ATOM 6834 O OD2 . ASP A 1 1037 ? 191.420 181.565 138.118 1.00 37.85  ? 1037 ASP A OD2 1 
ATOM 6835 N N   . THR A 1 1038 ? 190.349 179.703 135.696 1.00 41.46  ? 1038 THR A N   1 
ATOM 6836 C CA  . THR A 1 1038 ? 191.259 178.945 134.850 1.00 39.34  ? 1038 THR A CA  1 
ATOM 6837 C C   . THR A 1 1038 ? 192.594 178.633 135.517 1.00 39.92  ? 1038 THR A C   1 
ATOM 6838 O O   . THR A 1 1038 ? 193.349 177.814 134.980 1.00 41.73  ? 1038 THR A O   1 
ATOM 6839 C CB  . THR A 1 1038 ? 191.490 179.690 133.529 1.00 39.96  ? 1038 THR A CB  1 
ATOM 6840 O OG1 . THR A 1 1038 ? 192.086 180.968 133.788 1.00 44.20  ? 1038 THR A OG1 1 
ATOM 6841 C CG2 . THR A 1 1038 ? 190.174 179.885 132.788 1.00 39.57  ? 1038 THR A CG2 1 
ATOM 6842 N N   . GLU A 1 1039 ? 192.909 179.236 136.667 1.00 40.84  ? 1039 GLU A N   1 
ATOM 6843 C CA  . GLU A 1 1039 ? 194.136 178.879 137.371 1.00 41.37  ? 1039 GLU A CA  1 
ATOM 6844 C C   . GLU A 1 1039 ? 193.926 178.283 138.755 1.00 43.83  ? 1039 GLU A C   1 
ATOM 6845 O O   . GLU A 1 1039 ? 194.775 177.512 139.203 1.00 43.78  ? 1039 GLU A O   1 
ATOM 6846 C CB  . GLU A 1 1039 ? 195.085 180.086 137.482 1.00 41.82  ? 1039 GLU A CB  1 
ATOM 6847 C CG  . GLU A 1 1039 ? 194.642 181.281 138.324 1.00 45.17  ? 1039 GLU A CG  1 
ATOM 6848 C CD  . GLU A 1 1039 ? 195.671 182.402 138.270 1.00 45.20  ? 1039 GLU A CD  1 
ATOM 6849 O OE1 . GLU A 1 1039 ? 196.687 182.228 137.564 1.00 43.17  ? 1039 GLU A OE1 1 
ATOM 6850 O OE2 . GLU A 1 1039 ? 195.472 183.455 138.906 1.00 45.63  ? 1039 GLU A OE2 1 
ATOM 6851 N N   . ILE A 1 1040 ? 192.834 178.592 139.448 1.00 42.19  ? 1040 ILE A N   1 
ATOM 6852 C CA  . ILE A 1 1040 ? 192.587 178.045 140.779 1.00 40.03  ? 1040 ILE A CA  1 
ATOM 6853 C C   . ILE A 1 1040 ? 191.264 177.289 140.768 1.00 41.10  ? 1040 ILE A C   1 
ATOM 6854 O O   . ILE A 1 1040 ? 190.292 177.735 140.147 1.00 43.20  ? 1040 ILE A O   1 
ATOM 6855 C CB  . ILE A 1 1040 ? 192.594 179.140 141.863 1.00 41.28  ? 1040 ILE A CB  1 
ATOM 6856 C CG1 . ILE A 1 1040 ? 191.479 180.156 141.618 1.00 41.61  ? 1040 ILE A CG1 1 
ATOM 6857 C CG2 . ILE A 1 1040 ? 193.953 179.828 141.913 1.00 43.44  ? 1040 ILE A CG2 1 
ATOM 6858 C CD1 . ILE A 1 1040 ? 191.272 181.122 142.756 1.00 39.96  ? 1040 ILE A CD1 1 
ATOM 6859 N N   . THR A 1 1041 ? 191.239 176.134 141.431 1.00 36.88  ? 1041 THR A N   1 
ATOM 6860 C CA  . THR A 1 1041 ? 190.007 175.366 141.602 1.00 35.24  ? 1041 THR A CA  1 
ATOM 6861 C C   . THR A 1 1041 ? 189.275 175.938 142.809 1.00 34.23  ? 1041 THR A C   1 
ATOM 6862 O O   . THR A 1 1041 ? 189.643 175.680 143.957 1.00 36.33  ? 1041 THR A O   1 
ATOM 6863 C CB  . THR A 1 1041 ? 190.303 173.880 141.776 1.00 35.50  ? 1041 THR A CB  1 
ATOM 6864 O OG1 . THR A 1 1041 ? 191.193 173.444 140.741 1.00 35.12  ? 1041 THR A OG1 1 
ATOM 6865 C CG2 . THR A 1 1041 ? 189.016 173.065 141.700 1.00 32.79  ? 1041 THR A CG2 1 
ATOM 6866 N N   . THR A 1 1042 ? 188.236 176.724 142.550 1.00 28.25  ? 1042 THR A N   1 
ATOM 6867 C CA  . THR A 1 1042 ? 187.567 177.453 143.613 1.00 26.43  ? 1042 THR A CA  1 
ATOM 6868 C C   . THR A 1 1042 ? 186.734 176.513 144.478 1.00 27.00  ? 1042 THR A C   1 
ATOM 6869 O O   . THR A 1 1042 ? 186.595 175.317 144.204 1.00 28.10  ? 1042 THR A O   1 
ATOM 6870 C CB  . THR A 1 1042 ? 186.688 178.556 143.033 1.00 22.01  ? 1042 THR A CB  1 
ATOM 6871 O OG1 . THR A 1 1042 ? 185.621 177.974 142.273 1.00 19.07  ? 1042 THR A OG1 1 
ATOM 6872 C CG2 . THR A 1 1042 ? 187.512 179.444 142.137 1.00 23.75  ? 1042 THR A CG2 1 
ATOM 6873 N N   . PHE A 1 1043 ? 186.177 177.083 145.548 1.00 24.67  ? 1043 PHE A N   1 
ATOM 6874 C CA  . PHE A 1 1043 ? 185.395 176.288 146.486 1.00 21.26  ? 1043 PHE A CA  1 
ATOM 6875 C C   . PHE A 1 1043 ? 184.148 175.718 145.823 1.00 23.00  ? 1043 PHE A C   1 
ATOM 6876 O O   . PHE A 1 1043 ? 183.746 174.589 146.119 1.00 21.02  ? 1043 PHE A O   1 
ATOM 6877 C CB  . PHE A 1 1043 ? 185.030 177.127 147.713 1.00 22.94  ? 1043 PHE A CB  1 
ATOM 6878 C CG  . PHE A 1 1043 ? 183.885 176.571 148.517 1.00 23.93  ? 1043 PHE A CG  1 
ATOM 6879 C CD1 . PHE A 1 1043 ? 182.576 176.907 148.210 1.00 21.17  ? 1043 PHE A CD1 1 
ATOM 6880 C CD2 . PHE A 1 1043 ? 184.115 175.698 149.568 1.00 23.09  ? 1043 PHE A CD2 1 
ATOM 6881 C CE1 . PHE A 1 1043 ? 181.525 176.395 148.936 1.00 23.10  ? 1043 PHE A CE1 1 
ATOM 6882 C CE2 . PHE A 1 1043 ? 183.063 175.184 150.302 1.00 20.98  ? 1043 PHE A CE2 1 
ATOM 6883 C CZ  . PHE A 1 1043 ? 181.767 175.533 149.984 1.00 22.42  ? 1043 PHE A CZ  1 
ATOM 6884 N N   . GLU A 1 1044 ? 183.511 176.487 144.937 1.00 23.02  ? 1044 GLU A N   1 
ATOM 6885 C CA  . GLU A 1 1044 ? 182.287 176.003 144.308 1.00 16.78  ? 1044 GLU A CA  1 
ATOM 6886 C C   . GLU A 1 1044 ? 182.572 174.904 143.294 1.00 23.26  ? 1044 GLU A C   1 
ATOM 6887 O O   . GLU A 1 1044 ? 181.769 173.981 143.141 1.00 28.77  ? 1044 GLU A O   1 
ATOM 6888 C CB  . GLU A 1 1044 ? 181.524 177.153 143.656 1.00 16.26  ? 1044 GLU A CB  1 
ATOM 6889 C CG  . GLU A 1 1044 ? 181.320 178.340 144.555 1.00 19.93  ? 1044 GLU A CG  1 
ATOM 6890 C CD  . GLU A 1 1044 ? 180.350 179.344 143.975 1.00 22.05  ? 1044 GLU A CD  1 
ATOM 6891 O OE1 . GLU A 1 1044 ? 179.391 179.719 144.680 1.00 23.51  ? 1044 GLU A OE1 1 
ATOM 6892 O OE2 . GLU A 1 1044 ? 180.542 179.755 142.816 1.00 28.25  ? 1044 GLU A OE2 1 
ATOM 6893 N N   . GLU A 1 1045 ? 183.701 174.978 142.589 1.00 26.20  ? 1045 GLU A N   1 
ATOM 6894 C CA  . GLU A 1 1045 ? 184.063 173.901 141.670 1.00 20.67  ? 1045 GLU A CA  1 
ATOM 6895 C C   . GLU A 1 1045 ? 184.310 172.599 142.428 1.00 24.59  ? 1045 GLU A C   1 
ATOM 6896 O O   . GLU A 1 1045 ? 183.809 171.532 142.046 1.00 28.42  ? 1045 GLU A O   1 
ATOM 6897 C CB  . GLU A 1 1045 ? 185.294 174.304 140.860 1.00 22.41  ? 1045 GLU A CB  1 
ATOM 6898 C CG  . GLU A 1 1045 ? 185.746 173.271 139.845 1.00 30.78  ? 1045 GLU A CG  1 
ATOM 6899 C CD  . GLU A 1 1045 ? 186.852 173.788 138.948 1.00 31.75  ? 1045 GLU A CD  1 
ATOM 6900 O OE1 . GLU A 1 1045 ? 187.368 173.004 138.124 1.00 31.02  ? 1045 GLU A OE1 1 
ATOM 6901 O OE2 . GLU A 1 1045 ? 187.205 174.981 139.064 1.00 32.42  ? 1045 GLU A OE2 1 
ATOM 6902 N N   . THR A 1 1046 ? 185.075 172.677 143.520 1.00 24.06  ? 1046 THR A N   1 
ATOM 6903 C CA  . THR A 1 1046 ? 185.324 171.500 144.346 1.00 23.38  ? 1046 THR A CA  1 
ATOM 6904 C C   . THR A 1 1046 ? 184.033 170.976 144.960 1.00 21.80  ? 1046 THR A C   1 
ATOM 6905 O O   . THR A 1 1046 ? 183.812 169.762 145.015 1.00 27.71  ? 1046 THR A O   1 
ATOM 6906 C CB  . THR A 1 1046 ? 186.338 171.836 145.439 1.00 28.52  ? 1046 THR A CB  1 
ATOM 6907 O OG1 . THR A 1 1046 ? 187.580 172.223 144.840 1.00 34.42  ? 1046 THR A OG1 1 
ATOM 6908 C CG2 . THR A 1 1046 ? 186.568 170.637 146.346 1.00 29.62  ? 1046 THR A CG2 1 
ATOM 6909 N N   . LEU A 1 1047 ? 183.171 171.878 145.433 1.00 19.58  ? 1047 LEU A N   1 
ATOM 6910 C CA  . LEU A 1 1047 ? 181.893 171.470 146.000 1.00 17.26  ? 1047 LEU A CA  1 
ATOM 6911 C C   . LEU A 1 1047 ? 181.023 170.802 144.947 1.00 24.67  ? 1047 LEU A C   1 
ATOM 6912 O O   . LEU A 1 1047 ? 180.384 169.797 145.212 1.00 32.39  ? 1047 LEU A O   1 
ATOM 6913 C CB  . LEU A 1 1047 ? 181.180 172.680 146.602 1.00 16.76  ? 1047 LEU A CB  1 
ATOM 6914 C CG  . LEU A 1 1047 ? 179.832 172.433 147.272 1.00 22.29  ? 1047 LEU A CG  1 
ATOM 6915 C CD1 . LEU A 1 1047 ? 180.018 171.929 148.693 1.00 26.49  ? 1047 LEU A CD1 1 
ATOM 6916 C CD2 . LEU A 1 1047 ? 178.983 173.680 147.259 1.00 23.50  ? 1047 LEU A CD2 1 
ATOM 6917 N N   . ASP A 1 1048 ? 181.007 171.328 143.732 1.00 26.70  ? 1048 ASP A N   1 
ATOM 6918 C CA  . ASP A 1 1048 ? 180.234 170.707 142.663 1.00 18.73  ? 1048 ASP A CA  1 
ATOM 6919 C C   . ASP A 1 1048 ? 180.739 169.302 142.370 1.00 24.51  ? 1048 ASP A C   1 
ATOM 6920 O O   . ASP A 1 1048 ? 179.950 168.358 142.262 1.00 26.01  ? 1048 ASP A O   1 
ATOM 6921 C CB  . ASP A 1 1048 ? 180.302 171.580 141.410 1.00 24.26  ? 1048 ASP A CB  1 
ATOM 6922 C CG  . ASP A 1 1048 ? 179.428 171.063 140.290 1.00 32.52  ? 1048 ASP A CG  1 
ATOM 6923 O OD1 . ASP A 1 1048 ? 178.210 171.338 140.310 1.00 33.69  ? 1048 ASP A OD1 1 
ATOM 6924 O OD2 . ASP A 1 1048 ? 179.957 170.385 139.385 1.00 27.82  ? 1048 ASP A OD2 1 
ATOM 6925 N N   . ASP A 1 1049 ? 182.061 169.142 142.258 1.00 24.16  ? 1049 ASP A N   1 
ATOM 6926 C CA  . ASP A 1 1049 ? 182.617 167.817 141.995 1.00 25.34  ? 1049 ASP A CA  1 
ATOM 6927 C C   . ASP A 1 1049 ? 182.301 166.848 143.129 1.00 29.22  ? 1049 ASP A C   1 
ATOM 6928 O O   . ASP A 1 1049 ? 181.906 165.698 142.888 1.00 32.17  ? 1049 ASP A O   1 
ATOM 6929 C CB  . ASP A 1 1049 ? 184.126 167.917 141.780 1.00 25.25  ? 1049 ASP A CB  1 
ATOM 6930 C CG  . ASP A 1 1049 ? 184.484 168.629 140.491 1.00 34.05  ? 1049 ASP A CG  1 
ATOM 6931 O OD1 . ASP A 1 1049 ? 183.689 168.560 139.532 1.00 36.21  ? 1049 ASP A OD1 1 
ATOM 6932 O OD2 . ASP A 1 1049 ? 185.563 169.255 140.438 1.00 35.83  ? 1049 ASP A OD2 1 
ATOM 6933 N N   . LEU A 1 1050 ? 182.460 167.302 144.375 1.00 25.98  ? 1050 LEU A N   1 
ATOM 6934 C CA  . LEU A 1 1050 ? 182.181 166.453 145.527 1.00 22.28  ? 1050 LEU A CA  1 
ATOM 6935 C C   . LEU A 1 1050 ? 180.719 166.037 145.570 1.00 24.94  ? 1050 LEU A C   1 
ATOM 6936 O O   . LEU A 1 1050 ? 180.410 164.865 145.800 1.00 32.92  ? 1050 LEU A O   1 
ATOM 6937 C CB  . LEU A 1 1050 ? 182.559 167.182 146.814 1.00 29.89  ? 1050 LEU A CB  1 
ATOM 6938 C CG  . LEU A 1 1050 ? 184.039 167.336 147.152 1.00 30.09  ? 1050 LEU A CG  1 
ATOM 6939 C CD1 . LEU A 1 1050 ? 184.183 168.084 148.451 1.00 28.33  ? 1050 LEU A CD1 1 
ATOM 6940 C CD2 . LEU A 1 1050 ? 184.681 165.976 147.268 1.00 29.74  ? 1050 LEU A CD2 1 
ATOM 6941 N N   . LEU A 1 1051 ? 179.804 166.981 145.352 1.00 23.99  ? 1051 LEU A N   1 
ATOM 6942 C CA  . LEU A 1 1051 ? 178.383 166.655 145.392 1.00 21.83  ? 1051 LEU A CA  1 
ATOM 6943 C C   . LEU A 1 1051 ? 177.996 165.734 144.246 1.00 25.31  ? 1051 LEU A C   1 
ATOM 6944 O O   . LEU A 1 1051 ? 177.163 164.843 144.424 1.00 29.94  ? 1051 LEU A O   1 
ATOM 6945 C CB  . LEU A 1 1051 ? 177.545 167.934 145.372 1.00 23.97  ? 1051 LEU A CB  1 
ATOM 6946 C CG  . LEU A 1 1051 ? 177.454 168.678 146.706 1.00 21.26  ? 1051 LEU A CG  1 
ATOM 6947 C CD1 . LEU A 1 1051 ? 178.720 169.323 147.073 1.00 26.42  ? 1051 LEU A CD1 1 
ATOM 6948 C CD2 . LEU A 1 1051 ? 176.365 169.702 146.673 1.00 17.72  ? 1051 LEU A CD2 1 
ATOM 6949 N N   . GLN A 1 1052 ? 178.592 165.921 143.066 1.00 23.80  ? 1052 GLN A N   1 
ATOM 6950 C CA  . GLN A 1 1052 ? 178.311 165.018 141.954 1.00 26.96  ? 1052 GLN A CA  1 
ATOM 6951 C C   . GLN A 1 1052 ? 178.766 163.599 142.270 1.00 29.62  ? 1052 GLN A C   1 
ATOM 6952 O O   . GLN A 1 1052 ? 178.030 162.632 142.039 1.00 33.59  ? 1052 GLN A O   1 
ATOM 6953 C CB  . GLN A 1 1052 ? 178.977 165.528 140.675 1.00 28.52  ? 1052 GLN A CB  1 
ATOM 6954 C CG  . GLN A 1 1052 ? 178.403 166.834 140.151 1.00 33.15  ? 1052 GLN A CG  1 
ATOM 6955 C CD  . GLN A 1 1052 ? 179.102 167.317 138.896 1.00 35.72  ? 1052 GLN A CD  1 
ATOM 6956 O OE1 . GLN A 1 1052 ? 180.070 166.710 138.439 1.00 33.19  ? 1052 GLN A OE1 1 
ATOM 6957 N NE2 . GLN A 1 1052 ? 178.620 168.422 138.337 1.00 30.40  ? 1052 GLN A NE2 1 
ATOM 6958 N N   . ARG A 1 1053 ? 179.977 163.451 142.815 1.00 26.81  ? 1053 ARG A N   1 
ATOM 6959 C CA  . ARG A 1 1053 ? 180.464 162.114 143.146 1.00 23.58  ? 1053 ARG A CA  1 
ATOM 6960 C C   . ARG A 1 1053 ? 179.646 161.481 144.268 1.00 25.71  ? 1053 ARG A C   1 
ATOM 6961 O O   . ARG A 1 1053 ? 179.328 160.285 144.217 1.00 32.58  ? 1053 ARG A O   1 
ATOM 6962 C CB  . ARG A 1 1053 ? 181.949 162.164 143.507 1.00 24.94  ? 1053 ARG A CB  1 
ATOM 6963 C CG  . ARG A 1 1053 ? 182.850 162.309 142.290 1.00 29.93  ? 1053 ARG A CG  1 
ATOM 6964 C CD  . ARG A 1 1053 ? 184.328 162.234 142.639 1.00 29.73  ? 1053 ARG A CD  1 
ATOM 6965 N NE  . ARG A 1 1053 ? 184.713 163.159 143.697 1.00 34.06  ? 1053 ARG A NE  1 
ATOM 6966 C CZ  . ARG A 1 1053 ? 185.460 164.237 143.503 1.00 33.28  ? 1053 ARG A CZ  1 
ATOM 6967 N NH1 . ARG A 1 1053 ? 185.903 164.565 142.302 1.00 30.28  ? 1053 ARG A NH1 1 
ATOM 6968 N NH2 . ARG A 1 1053 ? 185.772 165.005 144.541 1.00 28.33  ? 1053 ARG A NH2 1 
ATOM 6969 N N   . ARG A 1 1054 ? 179.284 162.265 145.286 1.00 25.14  ? 1054 ARG A N   1 
ATOM 6970 C CA  . ARG A 1 1054 ? 178.477 161.724 146.375 1.00 26.55  ? 1054 ARG A CA  1 
ATOM 6971 C C   . ARG A 1 1054 ? 177.079 161.350 145.899 1.00 27.74  ? 1054 ARG A C   1 
ATOM 6972 O O   . ARG A 1 1054 ? 176.511 160.362 146.365 1.00 33.17  ? 1054 ARG A O   1 
ATOM 6973 C CB  . ARG A 1 1054 ? 178.405 162.717 147.534 1.00 25.10  ? 1054 ARG A CB  1 
ATOM 6974 C CG  . ARG A 1 1054 ? 179.742 163.042 148.178 1.00 28.17  ? 1054 ARG A CG  1 
ATOM 6975 C CD  . ARG A 1 1054 ? 180.550 161.786 148.463 1.00 29.63  ? 1054 ARG A CD  1 
ATOM 6976 N NE  . ARG A 1 1054 ? 181.588 162.011 149.462 1.00 29.91  ? 1054 ARG A NE  1 
ATOM 6977 C CZ  . ARG A 1 1054 ? 181.361 162.216 150.752 1.00 33.56  ? 1054 ARG A CZ  1 
ATOM 6978 N NH1 . ARG A 1 1054 ? 180.135 162.210 151.249 1.00 32.82  ? 1054 ARG A NH1 1 
ATOM 6979 N NH2 . ARG A 1 1054 ? 182.391 162.429 151.566 1.00 33.28  ? 1054 ARG A NH2 1 
ATOM 6980 N N   . ARG A 1 1055 ? 176.506 162.121 144.970 1.00 24.73  ? 1055 ARG A N   1 
ATOM 6981 C CA  . ARG A 1 1055 ? 175.208 161.761 144.407 1.00 23.98  ? 1055 ARG A CA  1 
ATOM 6982 C C   . ARG A 1 1055 ? 175.305 160.494 143.567 1.00 30.29  ? 1055 ARG A C   1 
ATOM 6983 O O   . ARG A 1 1055 ? 174.399 159.650 143.594 1.00 31.26  ? 1055 ARG A O   1 
ATOM 6984 C CB  . ARG A 1 1055 ? 174.664 162.924 143.577 1.00 25.84  ? 1055 ARG A CB  1 
ATOM 6985 C CG  . ARG A 1 1055 ? 173.252 162.724 143.058 1.00 26.49  ? 1055 ARG A CG  1 
ATOM 6986 C CD  . ARG A 1 1055 ? 172.765 163.954 142.307 1.00 25.68  ? 1055 ARG A CD  1 
ATOM 6987 N NE  . ARG A 1 1055 ? 172.518 165.080 143.200 1.00 29.70  ? 1055 ARG A NE  1 
ATOM 6988 C CZ  . ARG A 1 1055 ? 173.126 166.255 143.112 1.00 27.46  ? 1055 ARG A CZ  1 
ATOM 6989 N NH1 . ARG A 1 1055 ? 174.031 166.497 142.178 1.00 28.20  ? 1055 ARG A NH1 1 
ATOM 6990 N NH2 . ARG A 1 1055 ? 172.820 167.211 143.984 1.00 18.55  ? 1055 ARG A NH2 1 
ATOM 6991 N N   . ALA A 1 1056 ? 176.397 160.345 142.811 1.00 29.84  ? 1056 ALA A N   1 
ATOM 6992 C CA  . ALA A 1 1056 ? 176.606 159.120 142.048 1.00 24.76  ? 1056 ALA A CA  1 
ATOM 6993 C C   . ALA A 1 1056 ? 176.701 157.913 142.969 1.00 30.74  ? 1056 ALA A C   1 
ATOM 6994 O O   . ALA A 1 1056 ? 176.138 156.851 142.676 1.00 34.15  ? 1056 ALA A O   1 
ATOM 6995 C CB  . ALA A 1 1056 ? 177.862 159.243 141.187 1.00 24.24  ? 1056 ALA A CB  1 
ATOM 6996 N N   . LEU A 1 1057 ? 177.416 158.055 144.086 1.00 31.72  ? 1057 LEU A N   1 
ATOM 6997 C CA  . LEU A 1 1057 ? 177.457 156.982 145.074 1.00 27.54  ? 1057 LEU A CA  1 
ATOM 6998 C C   . LEU A 1 1057 ? 176.086 156.755 145.703 1.00 28.21  ? 1057 LEU A C   1 
ATOM 6999 O O   . LEU A 1 1057 ? 175.700 155.612 145.968 1.00 31.83  ? 1057 LEU A O   1 
ATOM 7000 C CB  . LEU A 1 1057 ? 178.498 157.294 146.148 1.00 27.93  ? 1057 LEU A CB  1 
ATOM 7001 C CG  . LEU A 1 1057 ? 179.954 157.404 145.689 1.00 29.69  ? 1057 LEU A CG  1 
ATOM 7002 C CD1 . LEU A 1 1057 ? 180.896 157.248 146.871 1.00 30.46  ? 1057 LEU A CD1 1 
ATOM 7003 C CD2 . LEU A 1 1057 ? 180.270 156.378 144.612 1.00 30.14  ? 1057 LEU A CD2 1 
ATOM 7004 N N   . ALA A 1 1058 ? 175.338 157.832 145.952 1.00 28.53  ? 1058 ALA A N   1 
ATOM 7005 C CA  . ALA A 1 1058 ? 174.032 157.757 146.591 1.00 27.85  ? 1058 ALA A CA  1 
ATOM 7006 C C   . ALA A 1 1058 ? 172.967 157.142 145.699 1.00 27.97  ? 1058 ALA A C   1 
ATOM 7007 O O   . ALA A 1 1058 ? 171.930 156.714 146.216 1.00 27.23  ? 1058 ALA A O   1 
ATOM 7008 C CB  . ALA A 1 1058 ? 173.586 159.150 147.036 1.00 30.77  ? 1058 ALA A CB  1 
ATOM 7009 N N   . ARG A 1 1059 ? 173.185 157.088 144.382 1.00 32.63  ? 1059 ARG A N   1 
ATOM 7010 C CA  . ARG A 1 1059 ? 172.286 156.301 143.545 1.00 33.23  ? 1059 ARG A CA  1 
ATOM 7011 C C   . ARG A 1 1059 ? 172.333 154.825 143.915 1.00 33.26  ? 1059 ARG A C   1 
ATOM 7012 O O   . ARG A 1 1059 ? 171.440 154.066 143.523 1.00 34.40  ? 1059 ARG A O   1 
ATOM 7013 C CB  . ARG A 1 1059 ? 172.618 156.481 142.061 1.00 32.33  ? 1059 ARG A CB  1 
ATOM 7014 C CG  . ARG A 1 1059 ? 172.330 157.873 141.519 1.00 34.36  ? 1059 ARG A CG  1 
ATOM 7015 C CD  . ARG A 1 1059 ? 172.682 157.980 140.042 1.00 35.29  ? 1059 ARG A CD  1 
ATOM 7016 N NE  . ARG A 1 1059 ? 172.384 159.303 139.504 1.00 36.12  ? 1059 ARG A NE  1 
ATOM 7017 C CZ  . ARG A 1 1059 ? 173.239 160.316 139.479 1.00 35.21  ? 1059 ARG A CZ  1 
ATOM 7018 N NH1 . ARG A 1 1059 ? 174.475 160.189 139.932 1.00 35.80  ? 1059 ARG A NH1 1 
ATOM 7019 N NH2 . ARG A 1 1059 ? 172.847 161.485 138.983 1.00 36.95  ? 1059 ARG A NH2 1 
ATOM 7020 N N   . ASP A 1 1060 ? 173.354 154.408 144.658 1.00 35.94  ? 1060 ASP A N   1 
ATOM 7021 C CA  . ASP A 1 1060 ? 173.424 153.072 145.227 1.00 32.48  ? 1060 ASP A CA  1 
ATOM 7022 C C   . ASP A 1 1060 ? 172.690 153.031 146.564 1.00 32.45  ? 1060 ASP A C   1 
ATOM 7023 O O   . ASP A 1 1060 ? 172.786 153.959 147.371 1.00 33.30  ? 1060 ASP A O   1 
ATOM 7024 C CB  . ASP A 1 1060 ? 174.882 152.651 145.410 1.00 29.67  ? 1060 ASP A CB  1 
ATOM 7025 C CG  . ASP A 1 1060 ? 175.023 151.212 145.842 1.00 33.42  ? 1060 ASP A CG  1 
ATOM 7026 O OD1 . ASP A 1 1060 ? 174.069 150.668 146.431 1.00 35.21  ? 1060 ASP A OD1 1 
ATOM 7027 O OD2 . ASP A 1 1060 ? 176.090 150.618 145.592 1.00 33.74  ? 1060 ASP A OD2 1 
ATOM 7028 N N   . MET A 1 1061 ? 171.969 151.931 146.796 1.00 30.11  ? 1061 MET A N   1 
ATOM 7029 C CA  . MET A 1 1061 ? 171.206 151.773 148.030 1.00 27.04  ? 1061 MET A CA  1 
ATOM 7030 C C   . MET A 1 1061 ? 172.066 151.288 149.187 1.00 30.69  ? 1061 MET A C   1 
ATOM 7031 O O   . MET A 1 1061 ? 171.846 151.697 150.332 1.00 32.91  ? 1061 MET A O   1 
ATOM 7032 C CB  . MET A 1 1061 ? 170.054 150.796 147.815 1.00 25.39  ? 1061 MET A CB  1 
ATOM 7033 C CG  . MET A 1 1061 ? 169.035 150.787 148.936 1.00 26.32  ? 1061 MET A CG  1 
ATOM 7034 S SD  . MET A 1 1061 ? 168.055 149.278 148.956 1.00 33.17  ? 1061 MET A SD  1 
ATOM 7035 C CE  . MET A 1 1061 ? 168.904 148.350 150.228 1.00 28.49  ? 1061 MET A CE  1 
ATOM 7036 N N   . LEU A 1 1062 ? 173.036 150.421 148.914 1.00 28.51  ? 1062 LEU A N   1 
ATOM 7037 C CA  . LEU A 1 1062 ? 173.871 149.829 149.947 1.00 24.90  ? 1062 LEU A CA  1 
ATOM 7038 C C   . LEU A 1 1062 ? 174.988 150.757 150.397 1.00 25.33  ? 1062 LEU A C   1 
ATOM 7039 O O   . LEU A 1 1062 ? 175.837 150.347 151.194 1.00 33.01  ? 1062 LEU A O   1 
ATOM 7040 C CB  . LEU A 1 1062 ? 174.463 148.506 149.453 1.00 28.87  ? 1062 LEU A CB  1 
ATOM 7041 C CG  . LEU A 1 1062 ? 173.509 147.429 148.928 1.00 26.96  ? 1062 LEU A CG  1 
ATOM 7042 C CD1 . LEU A 1 1062 ? 174.199 146.074 148.908 1.00 28.96  ? 1062 LEU A CD1 1 
ATOM 7043 C CD2 . LEU A 1 1062 ? 172.236 147.364 149.752 1.00 27.01  ? 1062 LEU A CD2 1 
ATOM 7044 N N   . CYS A 1 1063 ? 175.007 151.992 149.906 1.00 32.50  ? 1063 CYS A N   1 
ATOM 7045 C CA  . CYS A 1 1063 ? 176.078 152.936 150.187 1.00 33.42  ? 1063 CYS A CA  1 
ATOM 7046 C C   . CYS A 1 1063 ? 175.606 153.967 151.201 1.00 36.59  ? 1063 CYS A C   1 
ATOM 7047 O O   . CYS A 1 1063 ? 174.529 154.552 151.045 1.00 37.54  ? 1063 CYS A O   1 
ATOM 7048 C CB  . CYS A 1 1063 ? 176.536 153.631 148.904 1.00 34.34  ? 1063 CYS A CB  1 
ATOM 7049 S SG  . CYS A 1 1063 ? 177.717 152.678 147.923 1.00 50.87  ? 1063 CYS A SG  1 
ATOM 7050 N N   . ALA A 1 1064 ? 176.412 154.184 152.236 1.00 35.43  ? 1064 ALA A N   1 
ATOM 7051 C CA  . ALA A 1 1064 ? 176.130 155.196 153.244 1.00 35.20  ? 1064 ALA A CA  1 
ATOM 7052 C C   . ALA A 1 1064 ? 176.741 156.518 152.798 1.00 37.13  ? 1064 ALA A C   1 
ATOM 7053 O O   . ALA A 1 1064 ? 177.953 156.600 152.567 1.00 37.31  ? 1064 ALA A O   1 
ATOM 7054 C CB  . ALA A 1 1064 ? 176.681 154.775 154.604 1.00 32.12  ? 1064 ALA A CB  1 
ATOM 7055 N N   . THR A 1 1065 ? 175.907 157.547 152.680 1.00 38.45  ? 1065 THR A N   1 
ATOM 7056 C CA  . THR A 1 1065 ? 176.337 158.854 152.180 1.00 40.72  ? 1065 THR A CA  1 
ATOM 7057 C C   . THR A 1 1065 ? 176.164 159.908 153.262 1.00 40.59  ? 1065 THR A C   1 
ATOM 7058 O O   . THR A 1 1065 ? 175.056 160.448 153.436 1.00 40.24  ? 1065 THR A O   1 
ATOM 7059 C CB  . THR A 1 1065 ? 175.550 159.241 150.930 1.00 40.66  ? 1065 THR A CB  1 
ATOM 7060 O OG1 . THR A 1 1065 ? 174.209 159.586 151.299 1.00 39.79  ? 1065 THR A OG1 1 
ATOM 7061 C CG2 . THR A 1 1065 ? 175.514 158.081 149.948 1.00 39.63  ? 1065 THR A CG2 1 
ATOM 7062 N N   . PRO A 1 1066 ? 177.207 160.227 154.013 1.00 43.50  ? 1066 PRO A N   1 
ATOM 7063 C CA  . PRO A 1 1066 ? 177.120 161.280 155.029 1.00 44.99  ? 1066 PRO A CA  1 
ATOM 7064 C C   . PRO A 1 1066 ? 177.331 162.654 154.400 1.00 44.19  ? 1066 PRO A C   1 
ATOM 7065 O O   . PRO A 1 1066 ? 177.473 162.800 153.188 1.00 44.73  ? 1066 PRO A O   1 
ATOM 7066 C CB  . PRO A 1 1066 ? 178.255 160.927 155.993 1.00 45.43  ? 1066 PRO A CB  1 
ATOM 7067 C CG  . PRO A 1 1066 ? 179.240 160.198 155.147 1.00 43.18  ? 1066 PRO A CG  1 
ATOM 7068 C CD  . PRO A 1 1066 ? 178.435 159.424 154.149 1.00 40.90  ? 1066 PRO A CD  1 
ATOM 7069 N N   . ASP A 1 1067 ? 177.348 163.669 155.259 1.00 42.09  ? 1067 ASP A N   1 
ATOM 7070 C CA  . ASP A 1 1067 ? 177.625 165.022 154.810 1.00 41.02  ? 1067 ASP A CA  1 
ATOM 7071 C C   . ASP A 1 1067 ? 179.104 165.178 154.467 1.00 42.98  ? 1067 ASP A C   1 
ATOM 7072 O O   . ASP A 1 1067 ? 179.967 164.454 154.970 1.00 41.70  ? 1067 ASP A O   1 
ATOM 7073 C CB  . ASP A 1 1067 ? 177.234 166.037 155.885 1.00 40.46  ? 1067 ASP A CB  1 
ATOM 7074 C CG  . ASP A 1 1067 ? 175.744 166.287 155.935 1.00 43.88  ? 1067 ASP A CG  1 
ATOM 7075 O OD1 . ASP A 1 1067 ? 174.999 165.566 155.243 1.00 47.75  ? 1067 ASP A OD1 1 
ATOM 7076 O OD2 . ASP A 1 1067 ? 175.316 167.203 156.668 1.00 44.87  ? 1067 ASP A OD2 1 
ATOM 7077 N N   . LEU A 1 1068 ? 179.388 166.137 153.593 1.00 39.84  ? 1068 LEU A N   1 
ATOM 7078 C CA  . LEU A 1 1068 ? 180.770 166.476 153.287 1.00 36.55  ? 1068 LEU A CA  1 
ATOM 7079 C C   . LEU A 1 1068 ? 181.431 167.128 154.494 1.00 39.25  ? 1068 LEU A C   1 
ATOM 7080 O O   . LEU A 1 1068 ? 180.811 167.918 155.211 1.00 39.12  ? 1068 LEU A O   1 
ATOM 7081 C CB  . LEU A 1 1068 ? 180.838 167.412 152.083 1.00 36.18  ? 1068 LEU A CB  1 
ATOM 7082 C CG  . LEU A 1 1068 ? 180.472 166.822 150.722 1.00 36.88  ? 1068 LEU A CG  1 
ATOM 7083 C CD1 . LEU A 1 1068 ? 180.546 167.894 149.659 1.00 38.25  ? 1068 LEU A CD1 1 
ATOM 7084 C CD2 . LEU A 1 1068 ? 181.391 165.665 150.381 1.00 35.69  ? 1068 LEU A CD2 1 
ATOM 7085 N N   . ASN A 1 1069 ? 182.695 166.791 154.719 1.00 44.95  ? 1069 ASN A N   1 
ATOM 7086 C CA  . ASN A 1 1069 ? 183.484 167.362 155.798 1.00 42.97  ? 1069 ASN A CA  1 
ATOM 7087 C C   . ASN A 1 1069 ? 184.671 168.131 155.221 1.00 44.99  ? 1069 ASN A C   1 
ATOM 7088 O O   . ASN A 1 1069 ? 184.810 168.292 154.005 1.00 48.91  ? 1069 ASN A O   1 
ATOM 7089 C CB  . ASN A 1 1069 ? 183.911 166.267 156.786 1.00 44.76  ? 1069 ASN A CB  1 
ATOM 7090 C CG  . ASN A 1 1069 ? 184.940 165.300 156.211 1.00 48.32  ? 1069 ASN A CG  1 
ATOM 7091 O OD1 . ASN A 1 1069 ? 185.930 165.698 155.602 1.00 49.21  ? 1069 ASN A OD1 1 
ATOM 7092 N ND2 . ASN A 1 1069 ? 184.700 164.009 156.410 1.00 46.53  ? 1069 ASN A ND2 1 
ATOM 7093 N N   . CYS A 1 1070 ? 185.534 168.613 156.117 1.00 49.38  ? 1070 CYS A N   1 
ATOM 7094 C CA  . CYS A 1 1070 ? 186.663 169.437 155.695 1.00 49.82  ? 1070 CYS A CA  1 
ATOM 7095 C C   . CYS A 1 1070 ? 187.671 168.637 154.880 1.00 50.74  ? 1070 CYS A C   1 
ATOM 7096 O O   . CYS A 1 1070 ? 188.271 169.163 153.935 1.00 49.63  ? 1070 CYS A O   1 
ATOM 7097 C CB  . CYS A 1 1070 ? 187.340 170.057 156.915 1.00 53.36  ? 1070 CYS A CB  1 
ATOM 7098 S SG  . CYS A 1 1070 ? 186.194 170.809 158.073 1.00 58.37  ? 1070 CYS A SG  1 
ATOM 7099 N N   . ALA A 1 1071 ? 187.882 167.367 155.238 1.00 49.44  ? 1071 ALA A N   1 
ATOM 7100 C CA  . ALA A 1 1071 ? 188.880 166.559 154.544 1.00 48.90  ? 1071 ALA A CA  1 
ATOM 7101 C C   . ALA A 1 1071 ? 188.537 166.380 153.071 1.00 49.12  ? 1071 ALA A C   1 
ATOM 7102 O O   . ALA A 1 1071 ? 189.430 166.145 152.250 1.00 50.93  ? 1071 ALA A O   1 
ATOM 7103 C CB  . ALA A 1 1071 ? 189.028 165.199 155.226 1.00 49.00  ? 1071 ALA A CB  1 
ATOM 7104 N N   . ASP A 1 1072 ? 187.254 166.485 152.719 1.00 39.88  ? 1072 ASP A N   1 
ATOM 7105 C CA  . ASP A 1 1072 ? 186.857 166.425 151.318 1.00 39.42  ? 1072 ASP A CA  1 
ATOM 7106 C C   . ASP A 1 1072 ? 187.306 167.653 150.537 1.00 41.32  ? 1072 ASP A C   1 
ATOM 7107 O O   . ASP A 1 1072 ? 187.479 167.567 149.317 1.00 43.64  ? 1072 ASP A O   1 
ATOM 7108 C CB  . ASP A 1 1072 ? 185.341 166.266 151.212 1.00 39.05  ? 1072 ASP A CB  1 
ATOM 7109 C CG  . ASP A 1 1072 ? 184.887 164.839 151.428 1.00 42.45  ? 1072 ASP A CG  1 
ATOM 7110 O OD1 . ASP A 1 1072 ? 185.436 163.932 150.769 1.00 46.19  ? 1072 ASP A OD1 1 
ATOM 7111 O OD2 . ASP A 1 1072 ? 183.977 164.623 152.256 1.00 40.60  ? 1072 ASP A OD2 1 
ATOM 7112 N N   . PHE A 1 1073 ? 187.501 168.786 151.210 1.00 40.37  ? 1073 PHE A N   1 
ATOM 7113 C CA  . PHE A 1 1073 ? 187.860 170.042 150.566 1.00 40.54  ? 1073 PHE A CA  1 
ATOM 7114 C C   . PHE A 1 1073 ? 189.343 170.370 150.681 1.00 44.10  ? 1073 PHE A C   1 
ATOM 7115 O O   . PHE A 1 1073 ? 189.742 171.494 150.361 1.00 46.91  ? 1073 PHE A O   1 
ATOM 7116 C CB  . PHE A 1 1073 ? 187.033 171.185 151.154 1.00 42.81  ? 1073 PHE A CB  1 
ATOM 7117 C CG  . PHE A 1 1073 ? 185.565 171.080 150.868 1.00 39.41  ? 1073 PHE A CG  1 
ATOM 7118 C CD1 . PHE A 1 1073 ? 185.053 171.491 149.650 1.00 36.17  ? 1073 PHE A CD1 1 
ATOM 7119 C CD2 . PHE A 1 1073 ? 184.699 170.557 151.811 1.00 38.91  ? 1073 PHE A CD2 1 
ATOM 7120 C CE1 . PHE A 1 1073 ? 183.704 171.395 149.386 1.00 38.77  ? 1073 PHE A CE1 1 
ATOM 7121 C CE2 . PHE A 1 1073 ? 183.351 170.455 151.551 1.00 35.86  ? 1073 PHE A CE2 1 
ATOM 7122 C CZ  . PHE A 1 1073 ? 182.853 170.873 150.338 1.00 36.89  ? 1073 PHE A CZ  1 
ATOM 7123 N N   . GLU A 1 1074 ? 190.168 169.422 151.131 1.00 53.64  ? 1074 GLU A N   1 
ATOM 7124 C CA  . GLU A 1 1074 ? 191.593 169.688 151.292 1.00 55.45  ? 1074 GLU A CA  1 
ATOM 7125 C C   . GLU A 1 1074 ? 192.310 169.904 149.966 1.00 57.98  ? 1074 GLU A C   1 
ATOM 7126 O O   . GLU A 1 1074 ? 193.449 170.383 149.972 1.00 59.24  ? 1074 GLU A O   1 
ATOM 7127 C CB  . GLU A 1 1074 ? 192.259 168.548 152.063 1.00 54.30  ? 1074 GLU A CB  1 
ATOM 7128 C CG  . GLU A 1 1074 ? 191.775 168.415 153.496 1.00 57.14  ? 1074 GLU A CG  1 
ATOM 7129 C CD  . GLU A 1 1074 ? 192.700 167.575 154.353 1.00 59.71  ? 1074 GLU A CD  1 
ATOM 7130 O OE1 . GLU A 1 1074 ? 193.818 167.262 153.893 1.00 61.39  ? 1074 GLU A OE1 1 
ATOM 7131 O OE2 . GLU A 1 1074 ? 192.309 167.227 155.487 1.00 55.87  ? 1074 GLU A OE2 1 
ATOM 7132 N N   . THR A 1 1075 ? 191.681 169.568 148.838 1.00 60.11  ? 1075 THR A N   1 
ATOM 7133 C CA  . THR A 1 1075 ? 192.268 169.857 147.536 1.00 60.81  ? 1075 THR A CA  1 
ATOM 7134 C C   . THR A 1 1075 ? 192.319 171.349 147.233 1.00 61.23  ? 1075 THR A C   1 
ATOM 7135 O O   . THR A 1 1075 ? 193.036 171.752 146.311 1.00 60.89  ? 1075 THR A O   1 
ATOM 7136 C CB  . THR A 1 1075 ? 191.489 169.134 146.435 1.00 60.37  ? 1075 THR A CB  1 
ATOM 7137 O OG1 . THR A 1 1075 ? 192.171 169.286 145.184 1.00 62.18  ? 1075 THR A OG1 1 
ATOM 7138 C CG2 . THR A 1 1075 ? 190.085 169.702 146.314 1.00 57.42  ? 1075 THR A CG2 1 
ATOM 7139 N N   . ILE A 1 1076 ? 191.577 172.170 147.980 1.00 59.18  ? 1076 ILE A N   1 
ATOM 7140 C CA  . ILE A 1 1076 ? 191.625 173.616 147.783 1.00 60.82  ? 1076 ILE A CA  1 
ATOM 7141 C C   . ILE A 1 1076 ? 192.988 174.166 148.184 1.00 60.26  ? 1076 ILE A C   1 
ATOM 7142 O O   . ILE A 1 1076 ? 193.516 175.085 147.546 1.00 58.54  ? 1076 ILE A O   1 
ATOM 7143 C CB  . ILE A 1 1076 ? 190.486 174.292 148.569 1.00 59.59  ? 1076 ILE A CB  1 
ATOM 7144 C CG1 . ILE A 1 1076 ? 189.129 173.954 147.949 1.00 56.61  ? 1076 ILE A CG1 1 
ATOM 7145 C CG2 . ILE A 1 1076 ? 190.683 175.800 148.627 1.00 58.44  ? 1076 ILE A CG2 1 
ATOM 7146 C CD1 . ILE A 1 1076 ? 187.968 174.666 148.606 1.00 53.96  ? 1076 ILE A CD1 1 
ATOM 7147 N N   . LEU A 1 1077 ? 193.585 173.601 149.236 1.00 65.53  ? 1077 LEU A N   1 
ATOM 7148 C CA  . LEU A 1 1077 ? 194.796 174.176 149.817 1.00 67.04  ? 1077 LEU A CA  1 
ATOM 7149 C C   . LEU A 1 1077 ? 195.957 174.171 148.829 1.00 68.60  ? 1077 LEU A C   1 
ATOM 7150 O O   . LEU A 1 1077 ? 196.701 175.154 148.733 1.00 67.43  ? 1077 LEU A O   1 
ATOM 7151 C CB  . LEU A 1 1077 ? 195.168 173.419 151.091 1.00 64.76  ? 1077 LEU A CB  1 
ATOM 7152 C CG  . LEU A 1 1077 ? 193.992 173.063 152.002 1.00 66.31  ? 1077 LEU A CG  1 
ATOM 7153 C CD1 . LEU A 1 1077 ? 194.481 172.469 153.311 1.00 65.72  ? 1077 LEU A CD1 1 
ATOM 7154 C CD2 . LEU A 1 1077 ? 193.136 174.293 152.261 1.00 65.11  ? 1077 LEU A CD2 1 
ATOM 7155 N N   . LYS A 1 1078 ? 196.136 173.073 148.090 1.00 71.01  ? 1078 LYS A N   1 
ATOM 7156 C CA  . LYS A 1 1078 ? 197.234 173.013 147.131 1.00 70.20  ? 1078 LYS A CA  1 
ATOM 7157 C C   . LYS A 1 1078 ? 196.994 173.945 145.949 1.00 69.38  ? 1078 LYS A C   1 
ATOM 7158 O O   . LYS A 1 1078 ? 197.945 174.496 145.383 1.00 69.42  ? 1078 LYS A O   1 
ATOM 7159 C CB  . LYS A 1 1078 ? 197.446 171.575 146.654 1.00 70.54  ? 1078 LYS A CB  1 
ATOM 7160 C CG  . LYS A 1 1078 ? 196.251 170.957 145.940 1.00 69.62  ? 1078 LYS A CG  1 
ATOM 7161 C CD  . LYS A 1 1078 ? 196.490 169.488 145.606 1.00 70.23  ? 1078 LYS A CD  1 
ATOM 7162 C CE  . LYS A 1 1078 ? 197.183 168.743 146.741 1.00 70.49  ? 1078 LYS A CE  1 
ATOM 7163 N NZ  . LYS A 1 1078 ? 196.479 168.897 148.046 1.00 69.96  ? 1078 LYS A NZ  1 
ATOM 7164 N N   . GLY A 1 1079 ? 195.736 174.135 145.562 1.00 64.88  ? 1079 GLY A N   1 
ATOM 7165 C CA  . GLY A 1 1079 ? 195.409 175.001 144.445 1.00 65.20  ? 1079 GLY A CA  1 
ATOM 7166 C C   . GLY A 1 1079 ? 193.936 175.003 144.086 1.00 65.13  ? 1079 GLY A C   1 
ATOM 7167 O O   . GLY A 1 1079 ? 193.449 175.918 143.422 1.00 64.26  ? 1079 GLY A O   1 
# 
