data_8QRZ
# 
_entry.id   8QRZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8QRZ         pdb_00008qrz 10.2210/pdb8qrz/pdb 
WWPDB D_1292133884 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-23 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8QRZ 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              divne@kth.se 
_pdbx_contact_author.name_first         Christina 
_pdbx_contact_author.name_last          Divne 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5805-2693 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Furlanetto, V.' 1 ? 
'Kalyani, D.C.'  2 ? 
'Divne, C.'      3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Furlanetto, V.' 1 0000-0003-2875-0156 
primary 'Kalyani, D.C.'  2 0000-0001-5829-9357 
primary 'Srivastava, V.' 3 ?                   
primary 'Hallberg, B.M.' 4 0000-0002-6781-0345 
primary 'Ezcurra, I.'    5 0000-0001-9080-3031 
primary 'Divne, C.'      6 0000-0002-5805-2693 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sugar phosphate isomerase' 48768.133 4   ? ? ? ? 
2 non-polymer syn 'RUBIDIUM ION'              85.468    4   ? ? ? ? 
3 water       nat water                       18.015    374 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRLAE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRLAE
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'RUBIDIUM ION' RB  
3 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LEU n 
1 3   LEU n 
1 4   GLU n 
1 5   ARG n 
1 6   ASP n 
1 7   LEU n 
1 8   ILE n 
1 9   GLN n 
1 10  SER n 
1 11  VAL n 
1 12  GLY n 
1 13  PHE n 
1 14  ARG n 
1 15  ASN n 
1 16  VAL n 
1 17  ARG n 
1 18  GLU n 
1 19  GLY n 
1 20  GLY n 
1 21  GLU n 
1 22  ILE n 
1 23  THR n 
1 24  GLY n 
1 25  PHE n 
1 26  GLN n 
1 27  PHE n 
1 28  ARG n 
1 29  VAL n 
1 30  ARG n 
1 31  MET n 
1 32  PRO n 
1 33  SER n 
1 34  TYR n 
1 35  ARG n 
1 36  GLY n 
1 37  MET n 
1 38  ALA n 
1 39  ALA n 
1 40  SER n 
1 41  LEU n 
1 42  ILE n 
1 43  ASP n 
1 44  GLY n 
1 45  ILE n 
1 46  GLY n 
1 47  VAL n 
1 48  ARG n 
1 49  ILE n 
1 50  PRO n 
1 51  GLY n 
1 52  LEU n 
1 53  VAL n 
1 54  ASP n 
1 55  VAL n 
1 56  GLY n 
1 57  PRO n 
1 58  ASP n 
1 59  VAL n 
1 60  PRO n 
1 61  LEU n 
1 62  TRP n 
1 63  THR n 
1 64  LEU n 
1 65  GLN n 
1 66  GLY n 
1 67  GLN n 
1 68  GLN n 
1 69  TYR n 
1 70  THR n 
1 71  LEU n 
1 72  ALA n 
1 73  GLU n 
1 74  LEU n 
1 75  TRP n 
1 76  ASP n 
1 77  GLY n 
1 78  ASP n 
1 79  GLY n 
1 80  VAL n 
1 81  ARG n 
1 82  TRP n 
1 83  PRO n 
1 84  LEU n 
1 85  GLU n 
1 86  ASP n 
1 87  ALA n 
1 88  ALA n 
1 89  ILE n 
1 90  ILE n 
1 91  PHE n 
1 92  VAL n 
1 93  PRO n 
1 94  LEU n 
1 95  PRO n 
1 96  GLY n 
1 97  GLY n 
1 98  LEU n 
1 99  PRO n 
1 100 ASP n 
1 101 GLY n 
1 102 VAL n 
1 103 HIS n 
1 104 GLU n 
1 105 LEU n 
1 106 SER n 
1 107 ILE n 
1 108 GLU n 
1 109 LEU n 
1 110 ARG n 
1 111 LEU n 
1 112 ARG n 
1 113 MET n 
1 114 SER n 
1 115 TYR n 
1 116 ILE n 
1 117 PRO n 
1 118 GLN n 
1 119 GLU n 
1 120 HIS n 
1 121 GLN n 
1 122 PRO n 
1 123 SER n 
1 124 THR n 
1 125 TYR n 
1 126 ARG n 
1 127 VAL n 
1 128 THR n 
1 129 LYS n 
1 130 HIS n 
1 131 VAL n 
1 132 THR n 
1 133 LEU n 
1 134 ALA n 
1 135 PRO n 
1 136 GLU n 
1 137 ALA n 
1 138 SER n 
1 139 GLY n 
1 140 ALA n 
1 141 PRO n 
1 142 PHE n 
1 143 ARG n 
1 144 TYR n 
1 145 GLY n 
1 146 VAL n 
1 147 SER n 
1 148 LEU n 
1 149 TYR n 
1 150 SER n 
1 151 TYR n 
1 152 MET n 
1 153 SER n 
1 154 ASP n 
1 155 TYR n 
1 156 GLY n 
1 157 THR n 
1 158 VAL n 
1 159 MET n 
1 160 ASP n 
1 161 LEU n 
1 162 GLU n 
1 163 THR n 
1 164 ALA n 
1 165 MET n 
1 166 ALA n 
1 167 SER n 
1 168 ILE n 
1 169 ALA n 
1 170 ASP n 
1 171 LEU n 
1 172 GLY n 
1 173 ALA n 
1 174 THR n 
1 175 GLY n 
1 176 ILE n 
1 177 GLU n 
1 178 ILE n 
1 179 LEU n 
1 180 GLY n 
1 181 GLU n 
1 182 ALA n 
1 183 HIS n 
1 184 VAL n 
1 185 PRO n 
1 186 ASN n 
1 187 TYR n 
1 188 PRO n 
1 189 ASN n 
1 190 PRO n 
1 191 SER n 
1 192 ASP n 
1 193 GLU n 
1 194 TRP n 
1 195 VAL n 
1 196 GLU n 
1 197 GLN n 
1 198 TRP n 
1 199 PHE n 
1 200 ALA n 
1 201 LEU n 
1 202 LEU n 
1 203 SER n 
1 204 THR n 
1 205 TYR n 
1 206 GLY n 
1 207 LEU n 
1 208 GLU n 
1 209 PRO n 
1 210 THR n 
1 211 ASN n 
1 212 MET n 
1 213 GLY n 
1 214 SER n 
1 215 TRP n 
1 216 ILE n 
1 217 ASP n 
1 218 THR n 
1 219 ARG n 
1 220 LEU n 
1 221 HIS n 
1 222 SER n 
1 223 SER n 
1 224 GLY n 
1 225 PRO n 
1 226 ASN n 
1 227 GLY n 
1 228 ARG n 
1 229 ASP n 
1 230 MET n 
1 231 THR n 
1 232 VAL n 
1 233 GLU n 
1 234 GLU n 
1 235 GLY n 
1 236 ALA n 
1 237 ALA n 
1 238 ALA n 
1 239 LEU n 
1 240 GLN n 
1 241 ARG n 
1 242 ASP n 
1 243 LEU n 
1 244 ARG n 
1 245 LEU n 
1 246 ALA n 
1 247 LYS n 
1 248 ARG n 
1 249 LEU n 
1 250 GLY n 
1 251 PHE n 
1 252 ARG n 
1 253 PHE n 
1 254 VAL n 
1 255 ARG n 
1 256 PRO n 
1 257 LYS n 
1 258 ILE n 
1 259 GLY n 
1 260 VAL n 
1 261 VAL n 
1 262 SER n 
1 263 SER n 
1 264 ASP n 
1 265 LEU n 
1 266 ILE n 
1 267 PRO n 
1 268 HIS n 
1 269 PRO n 
1 270 ILE n 
1 271 TRP n 
1 272 THR n 
1 273 GLU n 
1 274 VAL n 
1 275 VAL n 
1 276 GLU n 
1 277 ALA n 
1 278 SER n 
1 279 LEU n 
1 280 PRO n 
1 281 LEU n 
1 282 ALA n 
1 283 GLU n 
1 284 GLU n 
1 285 LEU n 
1 286 ASP n 
1 287 VAL n 
1 288 ILE n 
1 289 ILE n 
1 290 CYS n 
1 291 PRO n 
1 292 GLU n 
1 293 ILE n 
1 294 HIS n 
1 295 SER n 
1 296 PRO n 
1 297 THR n 
1 298 PRO n 
1 299 ILE n 
1 300 LYS n 
1 301 HIS n 
1 302 GLU n 
1 303 VAL n 
1 304 VAL n 
1 305 ASP n 
1 306 ASP n 
1 307 TYR n 
1 308 ILE n 
1 309 ALA n 
1 310 LEU n 
1 311 ILE n 
1 312 ARG n 
1 313 ARG n 
1 314 THR n 
1 315 GLY n 
1 316 THR n 
1 317 LYS n 
1 318 HIS n 
1 319 PHE n 
1 320 GLY n 
1 321 LEU n 
1 322 LEU n 
1 323 LEU n 
1 324 ASP n 
1 325 THR n 
1 326 GLY n 
1 327 ILE n 
1 328 PHE n 
1 329 GLN n 
1 330 ASP n 
1 331 ARG n 
1 332 PRO n 
1 333 ILE n 
1 334 PRO n 
1 335 LEU n 
1 336 LYS n 
1 337 PRO n 
1 338 GLY n 
1 339 GLU n 
1 340 LEU n 
1 341 PRO n 
1 342 GLY n 
1 343 GLN n 
1 344 ARG n 
1 345 PRO n 
1 346 ALA n 
1 347 PHE n 
1 348 LEU n 
1 349 ASP n 
1 350 GLY n 
1 351 ILE n 
1 352 HIS n 
1 353 VAL n 
1 354 ASP n 
1 355 PRO n 
1 356 ASN n 
1 357 ASP n 
1 358 VAL n 
1 359 PHE n 
1 360 ASP n 
1 361 VAL n 
1 362 ILE n 
1 363 GLU n 
1 364 ASN n 
1 365 VAL n 
1 366 VAL n 
1 367 PHE n 
1 368 ILE n 
1 369 GLN n 
1 370 ALA n 
1 371 LYS n 
1 372 PHE n 
1 373 HIS n 
1 374 ASP n 
1 375 ILE n 
1 376 ASP n 
1 377 GLU n 
1 378 GLU n 
1 379 LEU n 
1 380 ASP n 
1 381 ASP n 
1 382 LYS n 
1 383 GLN n 
1 384 ILE n 
1 385 PRO n 
1 386 TRP n 
1 387 GLU n 
1 388 PRO n 
1 389 VAL n 
1 390 LEU n 
1 391 LYS n 
1 392 ALA n 
1 393 LEU n 
1 394 LYS n 
1 395 ASP n 
1 396 ALA n 
1 397 GLY n 
1 398 TYR n 
1 399 THR n 
1 400 GLY n 
1 401 TYR n 
1 402 LEU n 
1 403 SER n 
1 404 SER n 
1 405 GLU n 
1 406 TYR n 
1 407 GLU n 
1 408 GLY n 
1 409 GLU n 
1 410 ARG n 
1 411 GLU n 
1 412 PRO n 
1 413 TRP n 
1 414 ARG n 
1 415 SER n 
1 416 ILE n 
1 417 GLU n 
1 418 GLN n 
1 419 VAL n 
1 420 ARG n 
1 421 ARG n 
1 422 GLN n 
1 423 HIS n 
1 424 SER n 
1 425 LEU n 
1 426 ILE n 
1 427 ARG n 
1 428 GLN n 
1 429 ILE n 
1 430 ALA n 
1 431 ASP n 
1 432 ARG n 
1 433 LEU n 
1 434 ALA n 
1 435 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   435 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NS220_14145 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Microbacterium testaceum' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2033 
_entity_src_gen.pdbx_gene_src_variant              NS220 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               '(DE3)-T1' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pNIC-CTHO 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
RB  non-polymer         . 'RUBIDIUM ION'  ? 'Rb 1'           85.468  
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LEU 2   2   2   LEU LEU A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   ASP 6   6   6   ASP ASP A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ILE 8   8   8   ILE ILE A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  ARG 14  14  14  ARG ARG A . n 
A 1 15  ASN 15  15  15  ASN ASN A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  ARG 17  17  17  ARG ARG A . n 
A 1 18  GLU 18  18  18  GLU GLU A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  GLU 21  21  21  GLU GLU A . n 
A 1 22  ILE 22  22  22  ILE ILE A . n 
A 1 23  THR 23  23  23  THR THR A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  GLN 26  26  26  GLN GLN A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  ARG 30  30  30  ARG ARG A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  ARG 35  35  35  ARG ARG A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  MET 37  37  37  MET MET A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  ASP 43  43  43  ASP ASP A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  GLY 46  46  46  GLY GLY A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  PRO 50  50  50  PRO PRO A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  VAL 53  53  53  VAL VAL A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  GLY 56  56  56  GLY GLY A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  TRP 62  62  62  TRP TRP A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  GLN 65  65  65  GLN GLN A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  GLN 68  68  68  GLN GLN A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  THR 70  70  70  THR THR A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  ARG 81  81  81  ARG ARG A . n 
A 1 82  TRP 82  82  82  TRP TRP A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  LEU 84  84  84  LEU LEU A . n 
A 1 85  GLU 85  85  85  GLU GLU A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  PRO 93  93  93  PRO PRO A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  PRO 95  95  95  PRO PRO A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 ASP 100 100 100 ASP ASP A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 HIS 103 103 103 HIS HIS A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 GLU 108 108 108 GLU GLU A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ARG 110 110 110 ARG ARG A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 GLN 118 118 118 GLN GLN A . n 
A 1 119 GLU 119 119 119 GLU GLU A . n 
A 1 120 HIS 120 120 120 HIS HIS A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 ARG 126 126 126 ARG ARG A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 LYS 129 129 129 LYS LYS A . n 
A 1 130 HIS 130 130 130 HIS HIS A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 GLY 139 139 139 GLY GLY A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 PRO 141 141 141 PRO PRO A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 TYR 144 144 144 TYR TYR A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 TYR 149 149 149 TYR TYR A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 TYR 151 151 151 TYR TYR A . n 
A 1 152 MET 152 152 152 MET MET A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 ASP 154 154 154 ASP ASP A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 GLY 156 156 156 GLY GLY A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 MET 159 159 159 MET MET A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 MET 165 165 165 MET MET A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 SER 167 167 167 SER SER A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 GLY 172 172 172 GLY GLY A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 ILE 176 176 176 ILE ILE A . n 
A 1 177 GLU 177 177 177 GLU GLU A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 TYR 187 187 187 TYR TYR A . n 
A 1 188 PRO 188 188 188 PRO PRO A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 ASP 192 192 192 ASP ASP A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 TRP 194 194 194 TRP TRP A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 GLU 196 196 196 GLU GLU A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 TRP 198 198 198 TRP TRP A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 TYR 205 205 205 TYR TYR A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 GLU 208 208 208 GLU GLU A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 ASN 211 211 211 ASN ASN A . n 
A 1 212 MET 212 212 212 MET MET A . n 
A 1 213 GLY 213 213 213 GLY GLY A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 ILE 216 216 216 ILE ILE A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 ARG 219 219 219 ARG ARG A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 HIS 221 221 221 HIS HIS A . n 
A 1 222 SER 222 222 222 SER SER A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 ASN 226 226 226 ASN ASN A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 MET 230 230 230 MET MET A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 GLU 233 233 233 GLU GLU A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 GLY 235 235 235 GLY GLY A . n 
A 1 236 ALA 236 236 236 ALA ALA A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLN 240 240 240 GLN GLN A . n 
A 1 241 ARG 241 241 241 ARG ARG A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 ARG 244 244 244 ARG ARG A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 ARG 248 248 248 ARG ARG A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 ARG 252 252 252 ARG ARG A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ARG 255 255 255 ARG ARG A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 SER 262 262 262 SER SER A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ASP 264 264 264 ASP ASP A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 ILE 266 266 266 ILE ILE A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 HIS 268 268 268 HIS HIS A . n 
A 1 269 PRO 269 269 269 PRO PRO A . n 
A 1 270 ILE 270 270 270 ILE ILE A . n 
A 1 271 TRP 271 271 271 TRP TRP A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 VAL 274 274 274 VAL VAL A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 GLU 283 283 283 GLU GLU A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 ASP 286 286 286 ASP ASP A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 CYS 290 290 290 CYS CYS A . n 
A 1 291 PRO 291 291 291 PRO PRO A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 HIS 294 294 294 HIS HIS A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 PRO 298 298 298 PRO PRO A . n 
A 1 299 ILE 299 299 299 ILE ILE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 HIS 301 301 301 HIS HIS A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 ASP 305 305 305 ASP ASP A . n 
A 1 306 ASP 306 306 306 ASP ASP A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 ARG 312 312 312 ARG ARG A . n 
A 1 313 ARG 313 313 313 ARG ARG A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 HIS 318 318 318 HIS HIS A . n 
A 1 319 PHE 319 319 319 PHE PHE A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 PHE 328 328 328 PHE PHE A . n 
A 1 329 GLN 329 329 329 GLN GLN A . n 
A 1 330 ASP 330 330 330 ASP ASP A . n 
A 1 331 ARG 331 331 331 ARG ARG A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 ILE 333 333 333 ILE ILE A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 LEU 335 335 335 LEU LEU A . n 
A 1 336 LYS 336 336 336 LYS LYS A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 GLY 338 338 338 GLY GLY A . n 
A 1 339 GLU 339 339 339 GLU GLU A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 PRO 341 341 341 PRO PRO A . n 
A 1 342 GLY 342 342 342 GLY GLY A . n 
A 1 343 GLN 343 343 343 GLN GLN A . n 
A 1 344 ARG 344 344 344 ARG ARG A . n 
A 1 345 PRO 345 345 345 PRO PRO A . n 
A 1 346 ALA 346 346 346 ALA ALA A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 GLY 350 350 350 GLY GLY A . n 
A 1 351 ILE 351 351 351 ILE ILE A . n 
A 1 352 HIS 352 352 352 HIS HIS A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 ASP 354 354 354 ASP ASP A . n 
A 1 355 PRO 355 355 355 PRO PRO A . n 
A 1 356 ASN 356 356 356 ASN ASN A . n 
A 1 357 ASP 357 357 357 ASP ASP A . n 
A 1 358 VAL 358 358 358 VAL VAL A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 ASP 360 360 360 ASP ASP A . n 
A 1 361 VAL 361 361 361 VAL VAL A . n 
A 1 362 ILE 362 362 362 ILE ILE A . n 
A 1 363 GLU 363 363 363 GLU GLU A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 VAL 365 365 365 VAL VAL A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 PHE 367 367 367 PHE PHE A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 LYS 371 371 371 LYS LYS A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 HIS 373 373 373 HIS HIS A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 ASP 376 376 376 ASP ASP A . n 
A 1 377 GLU 377 377 377 GLU GLU A . n 
A 1 378 GLU 378 378 378 GLU GLU A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ASP 380 380 380 ASP ASP A . n 
A 1 381 ASP 381 381 381 ASP ASP A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 ILE 384 384 384 ILE ILE A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 TRP 386 386 386 TRP TRP A . n 
A 1 387 GLU 387 387 387 GLU GLU A . n 
A 1 388 PRO 388 388 388 PRO PRO A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 LYS 391 391 391 LYS LYS A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 ASP 395 395 395 ASP ASP A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 GLY 397 397 397 GLY GLY A . n 
A 1 398 TYR 398 398 398 TYR TYR A . n 
A 1 399 THR 399 399 399 THR THR A . n 
A 1 400 GLY 400 400 400 GLY GLY A . n 
A 1 401 TYR 401 401 401 TYR TYR A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 SER 403 403 403 SER SER A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 GLU 405 405 405 GLU GLU A . n 
A 1 406 TYR 406 406 406 TYR TYR A . n 
A 1 407 GLU 407 407 407 GLU GLU A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 GLU 409 409 409 GLU GLU A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 PRO 412 412 412 PRO PRO A . n 
A 1 413 TRP 413 413 413 TRP TRP A . n 
A 1 414 ARG 414 414 414 ARG ARG A . n 
A 1 415 SER 415 415 415 SER SER A . n 
A 1 416 ILE 416 416 416 ILE ILE A . n 
A 1 417 GLU 417 417 417 GLU GLU A . n 
A 1 418 GLN 418 418 418 GLN GLN A . n 
A 1 419 VAL 419 419 419 VAL VAL A . n 
A 1 420 ARG 420 420 420 ARG ARG A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 GLN 422 422 422 GLN GLN A . n 
A 1 423 HIS 423 423 423 HIS HIS A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 ILE 426 426 426 ILE ILE A . n 
A 1 427 ARG 427 427 427 ARG ARG A . n 
A 1 428 GLN 428 428 428 GLN GLN A . n 
A 1 429 ILE 429 429 429 ILE ILE A . n 
A 1 430 ALA 430 430 430 ALA ALA A . n 
A 1 431 ASP 431 431 431 ASP ASP A . n 
A 1 432 ARG 432 432 432 ARG ARG A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   LEU 2   2   2   LEU LEU B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   GLU 4   4   4   GLU GLU B . n 
B 1 5   ARG 5   5   5   ARG ARG B . n 
B 1 6   ASP 6   6   6   ASP ASP B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   ILE 8   8   8   ILE ILE B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  VAL 11  11  11  VAL VAL B . n 
B 1 12  GLY 12  12  12  GLY GLY B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  ARG 14  14  14  ARG ARG B . n 
B 1 15  ASN 15  15  15  ASN ASN B . n 
B 1 16  VAL 16  16  16  VAL VAL B . n 
B 1 17  ARG 17  17  17  ARG ARG B . n 
B 1 18  GLU 18  18  18  GLU GLU B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  GLY 20  20  20  GLY GLY B . n 
B 1 21  GLU 21  21  21  GLU GLU B . n 
B 1 22  ILE 22  22  22  ILE ILE B . n 
B 1 23  THR 23  23  23  THR THR B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  PHE 25  25  25  PHE PHE B . n 
B 1 26  GLN 26  26  26  GLN GLN B . n 
B 1 27  PHE 27  27  27  PHE PHE B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  ARG 30  30  30  ARG ARG B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  SER 33  33  33  SER SER B . n 
B 1 34  TYR 34  34  34  TYR TYR B . n 
B 1 35  ARG 35  35  35  ARG ARG B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  MET 37  37  37  MET MET B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  ILE 42  42  42  ILE ILE B . n 
B 1 43  ASP 43  43  43  ASP ASP B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  GLY 46  46  46  GLY GLY B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  ILE 49  49  49  ILE ILE B . n 
B 1 50  PRO 50  50  50  PRO PRO B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  VAL 53  53  53  VAL VAL B . n 
B 1 54  ASP 54  54  54  ASP ASP B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  GLY 56  56  56  GLY GLY B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  VAL 59  59  59  VAL VAL B . n 
B 1 60  PRO 60  60  60  PRO PRO B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  TRP 62  62  62  TRP TRP B . n 
B 1 63  THR 63  63  63  THR THR B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  GLN 65  65  65  GLN GLN B . n 
B 1 66  GLY 66  66  66  GLY GLY B . n 
B 1 67  GLN 67  67  67  GLN GLN B . n 
B 1 68  GLN 68  68  68  GLN GLN B . n 
B 1 69  TYR 69  69  69  TYR TYR B . n 
B 1 70  THR 70  70  70  THR THR B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  GLU 73  73  73  GLU GLU B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  TRP 75  75  75  TRP TRP B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  VAL 80  80  80  VAL VAL B . n 
B 1 81  ARG 81  81  81  ARG ARG B . n 
B 1 82  TRP 82  82  82  TRP TRP B . n 
B 1 83  PRO 83  83  83  PRO PRO B . n 
B 1 84  LEU 84  84  84  LEU LEU B . n 
B 1 85  GLU 85  85  85  GLU GLU B . n 
B 1 86  ASP 86  86  86  ASP ASP B . n 
B 1 87  ALA 87  87  87  ALA ALA B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  ILE 89  89  89  ILE ILE B . n 
B 1 90  ILE 90  90  90  ILE ILE B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  PRO 93  93  93  PRO PRO B . n 
B 1 94  LEU 94  94  94  LEU LEU B . n 
B 1 95  PRO 95  95  95  PRO PRO B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 ASP 100 100 100 ASP ASP B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 HIS 103 103 103 HIS HIS B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 GLU 108 108 108 GLU GLU B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 ARG 110 110 110 ARG ARG B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 MET 113 113 113 MET MET B . n 
B 1 114 SER 114 114 114 SER SER B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 PRO 117 117 117 PRO PRO B . n 
B 1 118 GLN 118 118 118 GLN GLN B . n 
B 1 119 GLU 119 119 119 GLU GLU B . n 
B 1 120 HIS 120 120 120 HIS HIS B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 TYR 125 125 125 TYR TYR B . n 
B 1 126 ARG 126 126 126 ARG ARG B . n 
B 1 127 VAL 127 127 127 VAL VAL B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 LYS 129 129 129 LYS LYS B . n 
B 1 130 HIS 130 130 130 HIS HIS B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 THR 132 132 132 THR THR B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 GLY 139 139 139 GLY GLY B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 PRO 141 141 141 PRO PRO B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 TYR 144 144 144 TYR TYR B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 VAL 146 146 146 VAL VAL B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 TYR 149 149 149 TYR TYR B . n 
B 1 150 SER 150 150 150 SER SER B . n 
B 1 151 TYR 151 151 151 TYR TYR B . n 
B 1 152 MET 152 152 152 MET MET B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 ASP 154 154 154 ASP ASP B . n 
B 1 155 TYR 155 155 155 TYR TYR B . n 
B 1 156 GLY 156 156 156 GLY GLY B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 VAL 158 158 158 VAL VAL B . n 
B 1 159 MET 159 159 159 MET MET B . n 
B 1 160 ASP 160 160 160 ASP ASP B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 GLU 162 162 162 GLU GLU B . n 
B 1 163 THR 163 163 163 THR THR B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 MET 165 165 165 MET MET B . n 
B 1 166 ALA 166 166 166 ALA ALA B . n 
B 1 167 SER 167 167 167 SER SER B . n 
B 1 168 ILE 168 168 168 ILE ILE B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 ASP 170 170 170 ASP ASP B . n 
B 1 171 LEU 171 171 171 LEU LEU B . n 
B 1 172 GLY 172 172 172 GLY GLY B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 THR 174 174 174 THR THR B . n 
B 1 175 GLY 175 175 175 GLY GLY B . n 
B 1 176 ILE 176 176 176 ILE ILE B . n 
B 1 177 GLU 177 177 177 GLU GLU B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 LEU 179 179 179 LEU LEU B . n 
B 1 180 GLY 180 180 180 GLY GLY B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 HIS 183 183 183 HIS HIS B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 TYR 187 187 187 TYR TYR B . n 
B 1 188 PRO 188 188 188 PRO PRO B . n 
B 1 189 ASN 189 189 189 ASN ASN B . n 
B 1 190 PRO 190 190 190 PRO PRO B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 ASP 192 192 192 ASP ASP B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 TRP 194 194 194 TRP TRP B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 GLU 196 196 196 GLU GLU B . n 
B 1 197 GLN 197 197 197 GLN GLN B . n 
B 1 198 TRP 198 198 198 TRP TRP B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 LEU 202 202 202 LEU LEU B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 THR 204 204 204 THR THR B . n 
B 1 205 TYR 205 205 205 TYR TYR B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 GLU 208 208 208 GLU GLU B . n 
B 1 209 PRO 209 209 209 PRO PRO B . n 
B 1 210 THR 210 210 210 THR THR B . n 
B 1 211 ASN 211 211 211 ASN ASN B . n 
B 1 212 MET 212 212 212 MET MET B . n 
B 1 213 GLY 213 213 213 GLY GLY B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 TRP 215 215 215 TRP TRP B . n 
B 1 216 ILE 216 216 216 ILE ILE B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 THR 218 218 218 THR THR B . n 
B 1 219 ARG 219 219 219 ARG ARG B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 HIS 221 221 221 HIS HIS B . n 
B 1 222 SER 222 222 222 SER SER B . n 
B 1 223 SER 223 223 223 SER SER B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 PRO 225 225 225 PRO PRO B . n 
B 1 226 ASN 226 226 226 ASN ASN B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 ARG 228 228 228 ARG ARG B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 MET 230 230 230 MET MET B . n 
B 1 231 THR 231 231 231 THR THR B . n 
B 1 232 VAL 232 232 232 VAL VAL B . n 
B 1 233 GLU 233 233 233 GLU GLU B . n 
B 1 234 GLU 234 234 234 GLU GLU B . n 
B 1 235 GLY 235 235 235 GLY GLY B . n 
B 1 236 ALA 236 236 236 ALA ALA B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 ALA 238 238 238 ALA ALA B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLN 240 240 240 GLN GLN B . n 
B 1 241 ARG 241 241 241 ARG ARG B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 ARG 244 244 244 ARG ARG B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 ALA 246 246 246 ALA ALA B . n 
B 1 247 LYS 247 247 247 LYS LYS B . n 
B 1 248 ARG 248 248 248 ARG ARG B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 GLY 250 250 250 GLY GLY B . n 
B 1 251 PHE 251 251 251 PHE PHE B . n 
B 1 252 ARG 252 252 252 ARG ARG B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 ARG 255 255 255 ARG ARG B . n 
B 1 256 PRO 256 256 256 PRO PRO B . n 
B 1 257 LYS 257 257 257 LYS LYS B . n 
B 1 258 ILE 258 258 258 ILE ILE B . n 
B 1 259 GLY 259 259 259 GLY GLY B . n 
B 1 260 VAL 260 260 260 VAL VAL B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 SER 262 262 262 SER SER B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 ASP 264 264 264 ASP ASP B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 ILE 266 266 266 ILE ILE B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 HIS 268 268 268 HIS HIS B . n 
B 1 269 PRO 269 269 269 PRO PRO B . n 
B 1 270 ILE 270 270 270 ILE ILE B . n 
B 1 271 TRP 271 271 271 TRP TRP B . n 
B 1 272 THR 272 272 272 THR THR B . n 
B 1 273 GLU 273 273 273 GLU GLU B . n 
B 1 274 VAL 274 274 274 VAL VAL B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 GLU 276 276 276 GLU GLU B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 SER 278 278 278 SER SER B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 PRO 280 280 280 PRO PRO B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 GLU 283 283 283 GLU GLU B . n 
B 1 284 GLU 284 284 284 GLU GLU B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 ASP 286 286 286 ASP ASP B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 ILE 288 288 288 ILE ILE B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 CYS 290 290 290 CYS CYS B . n 
B 1 291 PRO 291 291 291 PRO PRO B . n 
B 1 292 GLU 292 292 292 GLU GLU B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 HIS 294 294 294 HIS HIS B . n 
B 1 295 SER 295 295 295 SER SER B . n 
B 1 296 PRO 296 296 296 PRO PRO B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 PRO 298 298 298 PRO PRO B . n 
B 1 299 ILE 299 299 299 ILE ILE B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 HIS 301 301 301 HIS HIS B . n 
B 1 302 GLU 302 302 302 GLU GLU B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 ASP 305 305 305 ASP ASP B . n 
B 1 306 ASP 306 306 306 ASP ASP B . n 
B 1 307 TYR 307 307 307 TYR TYR B . n 
B 1 308 ILE 308 308 308 ILE ILE B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 ILE 311 311 311 ILE ILE B . n 
B 1 312 ARG 312 312 312 ARG ARG B . n 
B 1 313 ARG 313 313 313 ARG ARG B . n 
B 1 314 THR 314 314 314 THR THR B . n 
B 1 315 GLY 315 315 315 GLY GLY B . n 
B 1 316 THR 316 316 316 THR THR B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 HIS 318 318 318 HIS HIS B . n 
B 1 319 PHE 319 319 319 PHE PHE B . n 
B 1 320 GLY 320 320 320 GLY GLY B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 LEU 322 322 322 LEU LEU B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ASP 324 324 324 ASP ASP B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 GLY 326 326 326 GLY GLY B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 PHE 328 328 328 PHE PHE B . n 
B 1 329 GLN 329 329 329 GLN GLN B . n 
B 1 330 ASP 330 330 330 ASP ASP B . n 
B 1 331 ARG 331 331 331 ARG ARG B . n 
B 1 332 PRO 332 332 332 PRO PRO B . n 
B 1 333 ILE 333 333 333 ILE ILE B . n 
B 1 334 PRO 334 334 334 PRO PRO B . n 
B 1 335 LEU 335 335 335 LEU LEU B . n 
B 1 336 LYS 336 336 336 LYS LYS B . n 
B 1 337 PRO 337 337 337 PRO PRO B . n 
B 1 338 GLY 338 338 338 GLY GLY B . n 
B 1 339 GLU 339 339 339 GLU GLU B . n 
B 1 340 LEU 340 340 340 LEU LEU B . n 
B 1 341 PRO 341 341 341 PRO PRO B . n 
B 1 342 GLY 342 342 342 GLY GLY B . n 
B 1 343 GLN 343 343 343 GLN GLN B . n 
B 1 344 ARG 344 344 344 ARG ARG B . n 
B 1 345 PRO 345 345 345 PRO PRO B . n 
B 1 346 ALA 346 346 346 ALA ALA B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 ASP 349 349 349 ASP ASP B . n 
B 1 350 GLY 350 350 350 GLY GLY B . n 
B 1 351 ILE 351 351 351 ILE ILE B . n 
B 1 352 HIS 352 352 352 HIS HIS B . n 
B 1 353 VAL 353 353 353 VAL VAL B . n 
B 1 354 ASP 354 354 354 ASP ASP B . n 
B 1 355 PRO 355 355 355 PRO PRO B . n 
B 1 356 ASN 356 356 356 ASN ASN B . n 
B 1 357 ASP 357 357 357 ASP ASP B . n 
B 1 358 VAL 358 358 358 VAL VAL B . n 
B 1 359 PHE 359 359 359 PHE PHE B . n 
B 1 360 ASP 360 360 360 ASP ASP B . n 
B 1 361 VAL 361 361 361 VAL VAL B . n 
B 1 362 ILE 362 362 362 ILE ILE B . n 
B 1 363 GLU 363 363 363 GLU GLU B . n 
B 1 364 ASN 364 364 364 ASN ASN B . n 
B 1 365 VAL 365 365 365 VAL VAL B . n 
B 1 366 VAL 366 366 366 VAL VAL B . n 
B 1 367 PHE 367 367 367 PHE PHE B . n 
B 1 368 ILE 368 368 368 ILE ILE B . n 
B 1 369 GLN 369 369 369 GLN GLN B . n 
B 1 370 ALA 370 370 370 ALA ALA B . n 
B 1 371 LYS 371 371 371 LYS LYS B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 HIS 373 373 373 HIS HIS B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 ILE 375 375 375 ILE ILE B . n 
B 1 376 ASP 376 376 376 ASP ASP B . n 
B 1 377 GLU 377 377 377 GLU GLU B . n 
B 1 378 GLU 378 378 378 GLU GLU B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 ASP 380 380 380 ASP ASP B . n 
B 1 381 ASP 381 381 381 ASP ASP B . n 
B 1 382 LYS 382 382 382 LYS LYS B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 ILE 384 384 384 ILE ILE B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 TRP 386 386 386 TRP TRP B . n 
B 1 387 GLU 387 387 387 GLU GLU B . n 
B 1 388 PRO 388 388 388 PRO PRO B . n 
B 1 389 VAL 389 389 389 VAL VAL B . n 
B 1 390 LEU 390 390 390 LEU LEU B . n 
B 1 391 LYS 391 391 391 LYS LYS B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 LEU 393 393 393 LEU LEU B . n 
B 1 394 LYS 394 394 394 LYS LYS B . n 
B 1 395 ASP 395 395 395 ASP ASP B . n 
B 1 396 ALA 396 396 396 ALA ALA B . n 
B 1 397 GLY 397 397 397 GLY GLY B . n 
B 1 398 TYR 398 398 398 TYR TYR B . n 
B 1 399 THR 399 399 399 THR THR B . n 
B 1 400 GLY 400 400 400 GLY GLY B . n 
B 1 401 TYR 401 401 401 TYR TYR B . n 
B 1 402 LEU 402 402 402 LEU LEU B . n 
B 1 403 SER 403 403 403 SER SER B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 GLU 405 405 405 GLU GLU B . n 
B 1 406 TYR 406 406 406 TYR TYR B . n 
B 1 407 GLU 407 407 407 GLU GLU B . n 
B 1 408 GLY 408 408 408 GLY GLY B . n 
B 1 409 GLU 409 409 409 GLU GLU B . n 
B 1 410 ARG 410 410 410 ARG ARG B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 PRO 412 412 412 PRO PRO B . n 
B 1 413 TRP 413 413 413 TRP TRP B . n 
B 1 414 ARG 414 414 414 ARG ARG B . n 
B 1 415 SER 415 415 415 SER SER B . n 
B 1 416 ILE 416 416 416 ILE ILE B . n 
B 1 417 GLU 417 417 417 GLU GLU B . n 
B 1 418 GLN 418 418 418 GLN GLN B . n 
B 1 419 VAL 419 419 419 VAL VAL B . n 
B 1 420 ARG 420 420 420 ARG ARG B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 GLN 422 422 422 GLN GLN B . n 
B 1 423 HIS 423 423 423 HIS HIS B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 LEU 425 425 425 LEU LEU B . n 
B 1 426 ILE 426 426 426 ILE ILE B . n 
B 1 427 ARG 427 427 427 ARG ARG B . n 
B 1 428 GLN 428 428 428 GLN GLN B . n 
B 1 429 ILE 429 429 429 ILE ILE B . n 
B 1 430 ALA 430 430 430 ALA ALA B . n 
B 1 431 ASP 431 431 431 ASP ASP B . n 
B 1 432 ARG 432 432 432 ARG ARG B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 GLU 435 435 435 GLU GLU B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   LEU 2   2   2   LEU LEU C . n 
C 1 3   LEU 3   3   3   LEU LEU C . n 
C 1 4   GLU 4   4   4   GLU GLU C . n 
C 1 5   ARG 5   5   5   ARG ARG C . n 
C 1 6   ASP 6   6   6   ASP ASP C . n 
C 1 7   LEU 7   7   7   LEU LEU C . n 
C 1 8   ILE 8   8   8   ILE ILE C . n 
C 1 9   GLN 9   9   9   GLN GLN C . n 
C 1 10  SER 10  10  10  SER SER C . n 
C 1 11  VAL 11  11  11  VAL VAL C . n 
C 1 12  GLY 12  12  12  GLY GLY C . n 
C 1 13  PHE 13  13  13  PHE PHE C . n 
C 1 14  ARG 14  14  14  ARG ARG C . n 
C 1 15  ASN 15  15  15  ASN ASN C . n 
C 1 16  VAL 16  16  16  VAL VAL C . n 
C 1 17  ARG 17  17  17  ARG ARG C . n 
C 1 18  GLU 18  18  18  GLU GLU C . n 
C 1 19  GLY 19  19  19  GLY GLY C . n 
C 1 20  GLY 20  20  20  GLY GLY C . n 
C 1 21  GLU 21  21  21  GLU GLU C . n 
C 1 22  ILE 22  22  22  ILE ILE C . n 
C 1 23  THR 23  23  23  THR THR C . n 
C 1 24  GLY 24  24  24  GLY GLY C . n 
C 1 25  PHE 25  25  25  PHE PHE C . n 
C 1 26  GLN 26  26  26  GLN GLN C . n 
C 1 27  PHE 27  27  27  PHE PHE C . n 
C 1 28  ARG 28  28  28  ARG ARG C . n 
C 1 29  VAL 29  29  29  VAL VAL C . n 
C 1 30  ARG 30  30  30  ARG ARG C . n 
C 1 31  MET 31  31  31  MET MET C . n 
C 1 32  PRO 32  32  32  PRO PRO C . n 
C 1 33  SER 33  33  33  SER SER C . n 
C 1 34  TYR 34  34  34  TYR TYR C . n 
C 1 35  ARG 35  35  35  ARG ARG C . n 
C 1 36  GLY 36  36  36  GLY GLY C . n 
C 1 37  MET 37  37  37  MET MET C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  ALA 39  39  39  ALA ALA C . n 
C 1 40  SER 40  40  40  SER SER C . n 
C 1 41  LEU 41  41  41  LEU LEU C . n 
C 1 42  ILE 42  42  42  ILE ILE C . n 
C 1 43  ASP 43  43  43  ASP ASP C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  ILE 45  45  45  ILE ILE C . n 
C 1 46  GLY 46  46  46  GLY GLY C . n 
C 1 47  VAL 47  47  47  VAL VAL C . n 
C 1 48  ARG 48  48  48  ARG ARG C . n 
C 1 49  ILE 49  49  49  ILE ILE C . n 
C 1 50  PRO 50  50  50  PRO PRO C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  LEU 52  52  52  LEU LEU C . n 
C 1 53  VAL 53  53  53  VAL VAL C . n 
C 1 54  ASP 54  54  54  ASP ASP C . n 
C 1 55  VAL 55  55  55  VAL VAL C . n 
C 1 56  GLY 56  56  56  GLY GLY C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  ASP 58  58  58  ASP ASP C . n 
C 1 59  VAL 59  59  59  VAL VAL C . n 
C 1 60  PRO 60  60  60  PRO PRO C . n 
C 1 61  LEU 61  61  61  LEU LEU C . n 
C 1 62  TRP 62  62  62  TRP TRP C . n 
C 1 63  THR 63  63  63  THR THR C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  GLN 65  65  65  GLN GLN C . n 
C 1 66  GLY 66  66  66  GLY GLY C . n 
C 1 67  GLN 67  67  67  GLN GLN C . n 
C 1 68  GLN 68  68  68  GLN GLN C . n 
C 1 69  TYR 69  69  69  TYR TYR C . n 
C 1 70  THR 70  70  70  THR THR C . n 
C 1 71  LEU 71  71  71  LEU LEU C . n 
C 1 72  ALA 72  72  72  ALA ALA C . n 
C 1 73  GLU 73  73  73  GLU GLU C . n 
C 1 74  LEU 74  74  74  LEU LEU C . n 
C 1 75  TRP 75  75  75  TRP TRP C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  GLY 77  77  77  GLY GLY C . n 
C 1 78  ASP 78  78  78  ASP ASP C . n 
C 1 79  GLY 79  79  79  GLY GLY C . n 
C 1 80  VAL 80  80  80  VAL VAL C . n 
C 1 81  ARG 81  81  81  ARG ARG C . n 
C 1 82  TRP 82  82  82  TRP TRP C . n 
C 1 83  PRO 83  83  83  PRO PRO C . n 
C 1 84  LEU 84  84  84  LEU LEU C . n 
C 1 85  GLU 85  85  85  GLU GLU C . n 
C 1 86  ASP 86  86  86  ASP ASP C . n 
C 1 87  ALA 87  87  87  ALA ALA C . n 
C 1 88  ALA 88  88  88  ALA ALA C . n 
C 1 89  ILE 89  89  89  ILE ILE C . n 
C 1 90  ILE 90  90  90  ILE ILE C . n 
C 1 91  PHE 91  91  91  PHE PHE C . n 
C 1 92  VAL 92  92  92  VAL VAL C . n 
C 1 93  PRO 93  93  93  PRO PRO C . n 
C 1 94  LEU 94  94  94  LEU LEU C . n 
C 1 95  PRO 95  95  95  PRO PRO C . n 
C 1 96  GLY 96  96  96  GLY GLY C . n 
C 1 97  GLY 97  97  97  GLY GLY C . n 
C 1 98  LEU 98  98  98  LEU LEU C . n 
C 1 99  PRO 99  99  99  PRO PRO C . n 
C 1 100 ASP 100 100 100 ASP ASP C . n 
C 1 101 GLY 101 101 101 GLY GLY C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 HIS 103 103 103 HIS HIS C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 LEU 105 105 105 LEU LEU C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 ILE 107 107 107 ILE ILE C . n 
C 1 108 GLU 108 108 108 GLU GLU C . n 
C 1 109 LEU 109 109 109 LEU LEU C . n 
C 1 110 ARG 110 110 110 ARG ARG C . n 
C 1 111 LEU 111 111 111 LEU LEU C . n 
C 1 112 ARG 112 112 112 ARG ARG C . n 
C 1 113 MET 113 113 113 MET MET C . n 
C 1 114 SER 114 114 114 SER SER C . n 
C 1 115 TYR 115 115 115 TYR TYR C . n 
C 1 116 ILE 116 116 116 ILE ILE C . n 
C 1 117 PRO 117 117 117 PRO PRO C . n 
C 1 118 GLN 118 118 118 GLN GLN C . n 
C 1 119 GLU 119 119 119 GLU GLU C . n 
C 1 120 HIS 120 120 120 HIS HIS C . n 
C 1 121 GLN 121 121 121 GLN GLN C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 SER 123 123 123 SER SER C . n 
C 1 124 THR 124 124 124 THR THR C . n 
C 1 125 TYR 125 125 125 TYR TYR C . n 
C 1 126 ARG 126 126 126 ARG ARG C . n 
C 1 127 VAL 127 127 127 VAL VAL C . n 
C 1 128 THR 128 128 128 THR THR C . n 
C 1 129 LYS 129 129 129 LYS LYS C . n 
C 1 130 HIS 130 130 130 HIS HIS C . n 
C 1 131 VAL 131 131 131 VAL VAL C . n 
C 1 132 THR 132 132 132 THR THR C . n 
C 1 133 LEU 133 133 133 LEU LEU C . n 
C 1 134 ALA 134 134 134 ALA ALA C . n 
C 1 135 PRO 135 135 135 PRO PRO C . n 
C 1 136 GLU 136 136 136 GLU GLU C . n 
C 1 137 ALA 137 137 137 ALA ALA C . n 
C 1 138 SER 138 138 138 SER SER C . n 
C 1 139 GLY 139 139 139 GLY GLY C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 PRO 141 141 141 PRO PRO C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ARG 143 143 143 ARG ARG C . n 
C 1 144 TYR 144 144 144 TYR TYR C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 VAL 146 146 146 VAL VAL C . n 
C 1 147 SER 147 147 147 SER SER C . n 
C 1 148 LEU 148 148 148 LEU LEU C . n 
C 1 149 TYR 149 149 149 TYR TYR C . n 
C 1 150 SER 150 150 150 SER SER C . n 
C 1 151 TYR 151 151 151 TYR TYR C . n 
C 1 152 MET 152 152 152 MET MET C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 ASP 154 154 154 ASP ASP C . n 
C 1 155 TYR 155 155 155 TYR TYR C . n 
C 1 156 GLY 156 156 156 GLY GLY C . n 
C 1 157 THR 157 157 157 THR THR C . n 
C 1 158 VAL 158 158 158 VAL VAL C . n 
C 1 159 MET 159 159 159 MET MET C . n 
C 1 160 ASP 160 160 160 ASP ASP C . n 
C 1 161 LEU 161 161 161 LEU LEU C . n 
C 1 162 GLU 162 162 162 GLU GLU C . n 
C 1 163 THR 163 163 163 THR THR C . n 
C 1 164 ALA 164 164 164 ALA ALA C . n 
C 1 165 MET 165 165 165 MET MET C . n 
C 1 166 ALA 166 166 166 ALA ALA C . n 
C 1 167 SER 167 167 167 SER SER C . n 
C 1 168 ILE 168 168 168 ILE ILE C . n 
C 1 169 ALA 169 169 169 ALA ALA C . n 
C 1 170 ASP 170 170 170 ASP ASP C . n 
C 1 171 LEU 171 171 171 LEU LEU C . n 
C 1 172 GLY 172 172 172 GLY GLY C . n 
C 1 173 ALA 173 173 173 ALA ALA C . n 
C 1 174 THR 174 174 174 THR THR C . n 
C 1 175 GLY 175 175 175 GLY GLY C . n 
C 1 176 ILE 176 176 176 ILE ILE C . n 
C 1 177 GLU 177 177 177 GLU GLU C . n 
C 1 178 ILE 178 178 178 ILE ILE C . n 
C 1 179 LEU 179 179 179 LEU LEU C . n 
C 1 180 GLY 180 180 180 GLY GLY C . n 
C 1 181 GLU 181 181 181 GLU GLU C . n 
C 1 182 ALA 182 182 182 ALA ALA C . n 
C 1 183 HIS 183 183 183 HIS HIS C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 PRO 185 185 185 PRO PRO C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 TYR 187 187 187 TYR TYR C . n 
C 1 188 PRO 188 188 188 PRO PRO C . n 
C 1 189 ASN 189 189 189 ASN ASN C . n 
C 1 190 PRO 190 190 190 PRO PRO C . n 
C 1 191 SER 191 191 191 SER SER C . n 
C 1 192 ASP 192 192 192 ASP ASP C . n 
C 1 193 GLU 193 193 193 GLU GLU C . n 
C 1 194 TRP 194 194 194 TRP TRP C . n 
C 1 195 VAL 195 195 195 VAL VAL C . n 
C 1 196 GLU 196 196 196 GLU GLU C . n 
C 1 197 GLN 197 197 197 GLN GLN C . n 
C 1 198 TRP 198 198 198 TRP TRP C . n 
C 1 199 PHE 199 199 199 PHE PHE C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 LEU 201 201 201 LEU LEU C . n 
C 1 202 LEU 202 202 202 LEU LEU C . n 
C 1 203 SER 203 203 203 SER SER C . n 
C 1 204 THR 204 204 204 THR THR C . n 
C 1 205 TYR 205 205 205 TYR TYR C . n 
C 1 206 GLY 206 206 206 GLY GLY C . n 
C 1 207 LEU 207 207 207 LEU LEU C . n 
C 1 208 GLU 208 208 208 GLU GLU C . n 
C 1 209 PRO 209 209 209 PRO PRO C . n 
C 1 210 THR 210 210 210 THR THR C . n 
C 1 211 ASN 211 211 211 ASN ASN C . n 
C 1 212 MET 212 212 212 MET MET C . n 
C 1 213 GLY 213 213 213 GLY GLY C . n 
C 1 214 SER 214 214 214 SER SER C . n 
C 1 215 TRP 215 215 215 TRP TRP C . n 
C 1 216 ILE 216 216 216 ILE ILE C . n 
C 1 217 ASP 217 217 217 ASP ASP C . n 
C 1 218 THR 218 218 218 THR THR C . n 
C 1 219 ARG 219 219 219 ARG ARG C . n 
C 1 220 LEU 220 220 220 LEU LEU C . n 
C 1 221 HIS 221 221 221 HIS HIS C . n 
C 1 222 SER 222 222 222 SER SER C . n 
C 1 223 SER 223 223 223 SER SER C . n 
C 1 224 GLY 224 224 224 GLY GLY C . n 
C 1 225 PRO 225 225 225 PRO PRO C . n 
C 1 226 ASN 226 226 226 ASN ASN C . n 
C 1 227 GLY 227 227 227 GLY GLY C . n 
C 1 228 ARG 228 228 228 ARG ARG C . n 
C 1 229 ASP 229 229 229 ASP ASP C . n 
C 1 230 MET 230 230 230 MET MET C . n 
C 1 231 THR 231 231 231 THR THR C . n 
C 1 232 VAL 232 232 232 VAL VAL C . n 
C 1 233 GLU 233 233 233 GLU GLU C . n 
C 1 234 GLU 234 234 234 GLU GLU C . n 
C 1 235 GLY 235 235 235 GLY GLY C . n 
C 1 236 ALA 236 236 236 ALA ALA C . n 
C 1 237 ALA 237 237 237 ALA ALA C . n 
C 1 238 ALA 238 238 238 ALA ALA C . n 
C 1 239 LEU 239 239 239 LEU LEU C . n 
C 1 240 GLN 240 240 240 GLN GLN C . n 
C 1 241 ARG 241 241 241 ARG ARG C . n 
C 1 242 ASP 242 242 242 ASP ASP C . n 
C 1 243 LEU 243 243 243 LEU LEU C . n 
C 1 244 ARG 244 244 244 ARG ARG C . n 
C 1 245 LEU 245 245 245 LEU LEU C . n 
C 1 246 ALA 246 246 246 ALA ALA C . n 
C 1 247 LYS 247 247 247 LYS LYS C . n 
C 1 248 ARG 248 248 248 ARG ARG C . n 
C 1 249 LEU 249 249 249 LEU LEU C . n 
C 1 250 GLY 250 250 250 GLY GLY C . n 
C 1 251 PHE 251 251 251 PHE PHE C . n 
C 1 252 ARG 252 252 252 ARG ARG C . n 
C 1 253 PHE 253 253 253 PHE PHE C . n 
C 1 254 VAL 254 254 254 VAL VAL C . n 
C 1 255 ARG 255 255 255 ARG ARG C . n 
C 1 256 PRO 256 256 256 PRO PRO C . n 
C 1 257 LYS 257 257 257 LYS LYS C . n 
C 1 258 ILE 258 258 258 ILE ILE C . n 
C 1 259 GLY 259 259 259 GLY GLY C . n 
C 1 260 VAL 260 260 260 VAL VAL C . n 
C 1 261 VAL 261 261 261 VAL VAL C . n 
C 1 262 SER 262 262 262 SER SER C . n 
C 1 263 SER 263 263 263 SER SER C . n 
C 1 264 ASP 264 264 264 ASP ASP C . n 
C 1 265 LEU 265 265 265 LEU LEU C . n 
C 1 266 ILE 266 266 266 ILE ILE C . n 
C 1 267 PRO 267 267 267 PRO PRO C . n 
C 1 268 HIS 268 268 268 HIS HIS C . n 
C 1 269 PRO 269 269 269 PRO PRO C . n 
C 1 270 ILE 270 270 270 ILE ILE C . n 
C 1 271 TRP 271 271 271 TRP TRP C . n 
C 1 272 THR 272 272 272 THR THR C . n 
C 1 273 GLU 273 273 273 GLU GLU C . n 
C 1 274 VAL 274 274 274 VAL VAL C . n 
C 1 275 VAL 275 275 275 VAL VAL C . n 
C 1 276 GLU 276 276 276 GLU GLU C . n 
C 1 277 ALA 277 277 277 ALA ALA C . n 
C 1 278 SER 278 278 278 SER SER C . n 
C 1 279 LEU 279 279 279 LEU LEU C . n 
C 1 280 PRO 280 280 280 PRO PRO C . n 
C 1 281 LEU 281 281 281 LEU LEU C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 GLU 283 283 283 GLU GLU C . n 
C 1 284 GLU 284 284 284 GLU GLU C . n 
C 1 285 LEU 285 285 285 LEU LEU C . n 
C 1 286 ASP 286 286 286 ASP ASP C . n 
C 1 287 VAL 287 287 287 VAL VAL C . n 
C 1 288 ILE 288 288 288 ILE ILE C . n 
C 1 289 ILE 289 289 289 ILE ILE C . n 
C 1 290 CYS 290 290 290 CYS CYS C . n 
C 1 291 PRO 291 291 291 PRO PRO C . n 
C 1 292 GLU 292 292 292 GLU GLU C . n 
C 1 293 ILE 293 293 293 ILE ILE C . n 
C 1 294 HIS 294 294 294 HIS HIS C . n 
C 1 295 SER 295 295 295 SER SER C . n 
C 1 296 PRO 296 296 296 PRO PRO C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 PRO 298 298 298 PRO PRO C . n 
C 1 299 ILE 299 299 299 ILE ILE C . n 
C 1 300 LYS 300 300 300 LYS LYS C . n 
C 1 301 HIS 301 301 301 HIS HIS C . n 
C 1 302 GLU 302 302 302 GLU GLU C . n 
C 1 303 VAL 303 303 303 VAL VAL C . n 
C 1 304 VAL 304 304 304 VAL VAL C . n 
C 1 305 ASP 305 305 305 ASP ASP C . n 
C 1 306 ASP 306 306 306 ASP ASP C . n 
C 1 307 TYR 307 307 307 TYR TYR C . n 
C 1 308 ILE 308 308 308 ILE ILE C . n 
C 1 309 ALA 309 309 309 ALA ALA C . n 
C 1 310 LEU 310 310 310 LEU LEU C . n 
C 1 311 ILE 311 311 311 ILE ILE C . n 
C 1 312 ARG 312 312 312 ARG ARG C . n 
C 1 313 ARG 313 313 313 ARG ARG C . n 
C 1 314 THR 314 314 314 THR THR C . n 
C 1 315 GLY 315 315 315 GLY GLY C . n 
C 1 316 THR 316 316 316 THR THR C . n 
C 1 317 LYS 317 317 317 LYS LYS C . n 
C 1 318 HIS 318 318 318 HIS HIS C . n 
C 1 319 PHE 319 319 319 PHE PHE C . n 
C 1 320 GLY 320 320 320 GLY GLY C . n 
C 1 321 LEU 321 321 321 LEU LEU C . n 
C 1 322 LEU 322 322 322 LEU LEU C . n 
C 1 323 LEU 323 323 323 LEU LEU C . n 
C 1 324 ASP 324 324 324 ASP ASP C . n 
C 1 325 THR 325 325 325 THR THR C . n 
C 1 326 GLY 326 326 326 GLY GLY C . n 
C 1 327 ILE 327 327 327 ILE ILE C . n 
C 1 328 PHE 328 328 328 PHE PHE C . n 
C 1 329 GLN 329 329 329 GLN GLN C . n 
C 1 330 ASP 330 330 330 ASP ASP C . n 
C 1 331 ARG 331 331 331 ARG ARG C . n 
C 1 332 PRO 332 332 332 PRO PRO C . n 
C 1 333 ILE 333 333 333 ILE ILE C . n 
C 1 334 PRO 334 334 334 PRO PRO C . n 
C 1 335 LEU 335 335 335 LEU LEU C . n 
C 1 336 LYS 336 336 336 LYS LYS C . n 
C 1 337 PRO 337 337 337 PRO PRO C . n 
C 1 338 GLY 338 338 338 GLY GLY C . n 
C 1 339 GLU 339 339 339 GLU GLU C . n 
C 1 340 LEU 340 340 340 LEU LEU C . n 
C 1 341 PRO 341 341 341 PRO PRO C . n 
C 1 342 GLY 342 342 342 GLY GLY C . n 
C 1 343 GLN 343 343 343 GLN GLN C . n 
C 1 344 ARG 344 344 344 ARG ARG C . n 
C 1 345 PRO 345 345 345 PRO PRO C . n 
C 1 346 ALA 346 346 346 ALA ALA C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 LEU 348 348 348 LEU LEU C . n 
C 1 349 ASP 349 349 349 ASP ASP C . n 
C 1 350 GLY 350 350 350 GLY GLY C . n 
C 1 351 ILE 351 351 351 ILE ILE C . n 
C 1 352 HIS 352 352 352 HIS HIS C . n 
C 1 353 VAL 353 353 353 VAL VAL C . n 
C 1 354 ASP 354 354 354 ASP ASP C . n 
C 1 355 PRO 355 355 355 PRO PRO C . n 
C 1 356 ASN 356 356 356 ASN ASN C . n 
C 1 357 ASP 357 357 357 ASP ASP C . n 
C 1 358 VAL 358 358 358 VAL VAL C . n 
C 1 359 PHE 359 359 359 PHE PHE C . n 
C 1 360 ASP 360 360 360 ASP ASP C . n 
C 1 361 VAL 361 361 361 VAL VAL C . n 
C 1 362 ILE 362 362 362 ILE ILE C . n 
C 1 363 GLU 363 363 363 GLU GLU C . n 
C 1 364 ASN 364 364 364 ASN ASN C . n 
C 1 365 VAL 365 365 365 VAL VAL C . n 
C 1 366 VAL 366 366 366 VAL VAL C . n 
C 1 367 PHE 367 367 367 PHE PHE C . n 
C 1 368 ILE 368 368 368 ILE ILE C . n 
C 1 369 GLN 369 369 369 GLN GLN C . n 
C 1 370 ALA 370 370 370 ALA ALA C . n 
C 1 371 LYS 371 371 371 LYS LYS C . n 
C 1 372 PHE 372 372 372 PHE PHE C . n 
C 1 373 HIS 373 373 373 HIS HIS C . n 
C 1 374 ASP 374 374 374 ASP ASP C . n 
C 1 375 ILE 375 375 375 ILE ILE C . n 
C 1 376 ASP 376 376 376 ASP ASP C . n 
C 1 377 GLU 377 377 377 GLU GLU C . n 
C 1 378 GLU 378 378 378 GLU GLU C . n 
C 1 379 LEU 379 379 379 LEU LEU C . n 
C 1 380 ASP 380 380 380 ASP ASP C . n 
C 1 381 ASP 381 381 381 ASP ASP C . n 
C 1 382 LYS 382 382 382 LYS LYS C . n 
C 1 383 GLN 383 383 383 GLN GLN C . n 
C 1 384 ILE 384 384 384 ILE ILE C . n 
C 1 385 PRO 385 385 385 PRO PRO C . n 
C 1 386 TRP 386 386 386 TRP TRP C . n 
C 1 387 GLU 387 387 387 GLU GLU C . n 
C 1 388 PRO 388 388 388 PRO PRO C . n 
C 1 389 VAL 389 389 389 VAL VAL C . n 
C 1 390 LEU 390 390 390 LEU LEU C . n 
C 1 391 LYS 391 391 391 LYS LYS C . n 
C 1 392 ALA 392 392 392 ALA ALA C . n 
C 1 393 LEU 393 393 393 LEU LEU C . n 
C 1 394 LYS 394 394 394 LYS LYS C . n 
C 1 395 ASP 395 395 395 ASP ASP C . n 
C 1 396 ALA 396 396 396 ALA ALA C . n 
C 1 397 GLY 397 397 397 GLY GLY C . n 
C 1 398 TYR 398 398 398 TYR TYR C . n 
C 1 399 THR 399 399 399 THR THR C . n 
C 1 400 GLY 400 400 400 GLY GLY C . n 
C 1 401 TYR 401 401 401 TYR TYR C . n 
C 1 402 LEU 402 402 402 LEU LEU C . n 
C 1 403 SER 403 403 403 SER SER C . n 
C 1 404 SER 404 404 404 SER SER C . n 
C 1 405 GLU 405 405 405 GLU GLU C . n 
C 1 406 TYR 406 406 406 TYR TYR C . n 
C 1 407 GLU 407 407 407 GLU GLU C . n 
C 1 408 GLY 408 408 408 GLY GLY C . n 
C 1 409 GLU 409 409 409 GLU GLU C . n 
C 1 410 ARG 410 410 410 ARG ARG C . n 
C 1 411 GLU 411 411 411 GLU GLU C . n 
C 1 412 PRO 412 412 412 PRO PRO C . n 
C 1 413 TRP 413 413 413 TRP TRP C . n 
C 1 414 ARG 414 414 414 ARG ARG C . n 
C 1 415 SER 415 415 415 SER SER C . n 
C 1 416 ILE 416 416 416 ILE ILE C . n 
C 1 417 GLU 417 417 417 GLU GLU C . n 
C 1 418 GLN 418 418 418 GLN GLN C . n 
C 1 419 VAL 419 419 419 VAL VAL C . n 
C 1 420 ARG 420 420 420 ARG ARG C . n 
C 1 421 ARG 421 421 421 ARG ARG C . n 
C 1 422 GLN 422 422 422 GLN GLN C . n 
C 1 423 HIS 423 423 423 HIS HIS C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 LEU 425 425 425 LEU LEU C . n 
C 1 426 ILE 426 426 426 ILE ILE C . n 
C 1 427 ARG 427 427 427 ARG ARG C . n 
C 1 428 GLN 428 428 428 GLN GLN C . n 
C 1 429 ILE 429 429 429 ILE ILE C . n 
C 1 430 ALA 430 430 430 ALA ALA C . n 
C 1 431 ASP 431 431 431 ASP ASP C . n 
C 1 432 ARG 432 432 432 ARG ARG C . n 
C 1 433 LEU 433 433 433 LEU LEU C . n 
C 1 434 ALA 434 434 434 ALA ALA C . n 
C 1 435 GLU 435 435 435 GLU GLU C . n 
D 1 1   MET 1   1   1   MET MET D . n 
D 1 2   LEU 2   2   2   LEU LEU D . n 
D 1 3   LEU 3   3   3   LEU LEU D . n 
D 1 4   GLU 4   4   4   GLU GLU D . n 
D 1 5   ARG 5   5   5   ARG ARG D . n 
D 1 6   ASP 6   6   6   ASP ASP D . n 
D 1 7   LEU 7   7   7   LEU LEU D . n 
D 1 8   ILE 8   8   8   ILE ILE D . n 
D 1 9   GLN 9   9   9   GLN GLN D . n 
D 1 10  SER 10  10  10  SER SER D . n 
D 1 11  VAL 11  11  11  VAL VAL D . n 
D 1 12  GLY 12  12  12  GLY GLY D . n 
D 1 13  PHE 13  13  13  PHE PHE D . n 
D 1 14  ARG 14  14  14  ARG ARG D . n 
D 1 15  ASN 15  15  15  ASN ASN D . n 
D 1 16  VAL 16  16  16  VAL VAL D . n 
D 1 17  ARG 17  17  17  ARG ARG D . n 
D 1 18  GLU 18  18  18  GLU GLU D . n 
D 1 19  GLY 19  19  19  GLY GLY D . n 
D 1 20  GLY 20  20  20  GLY GLY D . n 
D 1 21  GLU 21  21  21  GLU GLU D . n 
D 1 22  ILE 22  22  22  ILE ILE D . n 
D 1 23  THR 23  23  23  THR THR D . n 
D 1 24  GLY 24  24  24  GLY GLY D . n 
D 1 25  PHE 25  25  25  PHE PHE D . n 
D 1 26  GLN 26  26  26  GLN GLN D . n 
D 1 27  PHE 27  27  27  PHE PHE D . n 
D 1 28  ARG 28  28  28  ARG ARG D . n 
D 1 29  VAL 29  29  29  VAL VAL D . n 
D 1 30  ARG 30  30  30  ARG ARG D . n 
D 1 31  MET 31  31  31  MET MET D . n 
D 1 32  PRO 32  32  32  PRO PRO D . n 
D 1 33  SER 33  33  33  SER SER D . n 
D 1 34  TYR 34  34  34  TYR TYR D . n 
D 1 35  ARG 35  35  35  ARG ARG D . n 
D 1 36  GLY 36  36  36  GLY GLY D . n 
D 1 37  MET 37  37  37  MET MET D . n 
D 1 38  ALA 38  38  38  ALA ALA D . n 
D 1 39  ALA 39  39  39  ALA ALA D . n 
D 1 40  SER 40  40  40  SER SER D . n 
D 1 41  LEU 41  41  41  LEU LEU D . n 
D 1 42  ILE 42  42  42  ILE ILE D . n 
D 1 43  ASP 43  43  43  ASP ASP D . n 
D 1 44  GLY 44  44  44  GLY GLY D . n 
D 1 45  ILE 45  45  45  ILE ILE D . n 
D 1 46  GLY 46  46  46  GLY GLY D . n 
D 1 47  VAL 47  47  47  VAL VAL D . n 
D 1 48  ARG 48  48  48  ARG ARG D . n 
D 1 49  ILE 49  49  49  ILE ILE D . n 
D 1 50  PRO 50  50  50  PRO PRO D . n 
D 1 51  GLY 51  51  51  GLY GLY D . n 
D 1 52  LEU 52  52  52  LEU LEU D . n 
D 1 53  VAL 53  53  53  VAL VAL D . n 
D 1 54  ASP 54  54  54  ASP ASP D . n 
D 1 55  VAL 55  55  55  VAL VAL D . n 
D 1 56  GLY 56  56  56  GLY GLY D . n 
D 1 57  PRO 57  57  57  PRO PRO D . n 
D 1 58  ASP 58  58  58  ASP ASP D . n 
D 1 59  VAL 59  59  59  VAL VAL D . n 
D 1 60  PRO 60  60  60  PRO PRO D . n 
D 1 61  LEU 61  61  61  LEU LEU D . n 
D 1 62  TRP 62  62  62  TRP TRP D . n 
D 1 63  THR 63  63  63  THR THR D . n 
D 1 64  LEU 64  64  64  LEU LEU D . n 
D 1 65  GLN 65  65  65  GLN GLN D . n 
D 1 66  GLY 66  66  66  GLY GLY D . n 
D 1 67  GLN 67  67  67  GLN GLN D . n 
D 1 68  GLN 68  68  68  GLN GLN D . n 
D 1 69  TYR 69  69  69  TYR TYR D . n 
D 1 70  THR 70  70  70  THR THR D . n 
D 1 71  LEU 71  71  71  LEU LEU D . n 
D 1 72  ALA 72  72  72  ALA ALA D . n 
D 1 73  GLU 73  73  73  GLU GLU D . n 
D 1 74  LEU 74  74  74  LEU LEU D . n 
D 1 75  TRP 75  75  75  TRP TRP D . n 
D 1 76  ASP 76  76  76  ASP ASP D . n 
D 1 77  GLY 77  77  77  GLY GLY D . n 
D 1 78  ASP 78  78  78  ASP ASP D . n 
D 1 79  GLY 79  79  79  GLY GLY D . n 
D 1 80  VAL 80  80  80  VAL VAL D . n 
D 1 81  ARG 81  81  81  ARG ARG D . n 
D 1 82  TRP 82  82  82  TRP TRP D . n 
D 1 83  PRO 83  83  83  PRO PRO D . n 
D 1 84  LEU 84  84  84  LEU LEU D . n 
D 1 85  GLU 85  85  85  GLU GLU D . n 
D 1 86  ASP 86  86  86  ASP ASP D . n 
D 1 87  ALA 87  87  87  ALA ALA D . n 
D 1 88  ALA 88  88  88  ALA ALA D . n 
D 1 89  ILE 89  89  89  ILE ILE D . n 
D 1 90  ILE 90  90  90  ILE ILE D . n 
D 1 91  PHE 91  91  91  PHE PHE D . n 
D 1 92  VAL 92  92  92  VAL VAL D . n 
D 1 93  PRO 93  93  93  PRO PRO D . n 
D 1 94  LEU 94  94  94  LEU LEU D . n 
D 1 95  PRO 95  95  95  PRO PRO D . n 
D 1 96  GLY 96  96  96  GLY GLY D . n 
D 1 97  GLY 97  97  97  GLY GLY D . n 
D 1 98  LEU 98  98  98  LEU LEU D . n 
D 1 99  PRO 99  99  99  PRO PRO D . n 
D 1 100 ASP 100 100 100 ASP ASP D . n 
D 1 101 GLY 101 101 101 GLY GLY D . n 
D 1 102 VAL 102 102 102 VAL VAL D . n 
D 1 103 HIS 103 103 103 HIS HIS D . n 
D 1 104 GLU 104 104 104 GLU GLU D . n 
D 1 105 LEU 105 105 105 LEU LEU D . n 
D 1 106 SER 106 106 106 SER SER D . n 
D 1 107 ILE 107 107 107 ILE ILE D . n 
D 1 108 GLU 108 108 108 GLU GLU D . n 
D 1 109 LEU 109 109 109 LEU LEU D . n 
D 1 110 ARG 110 110 110 ARG ARG D . n 
D 1 111 LEU 111 111 111 LEU LEU D . n 
D 1 112 ARG 112 112 112 ARG ARG D . n 
D 1 113 MET 113 113 113 MET MET D . n 
D 1 114 SER 114 114 114 SER SER D . n 
D 1 115 TYR 115 115 115 TYR TYR D . n 
D 1 116 ILE 116 116 116 ILE ILE D . n 
D 1 117 PRO 117 117 117 PRO PRO D . n 
D 1 118 GLN 118 118 118 GLN GLN D . n 
D 1 119 GLU 119 119 119 GLU GLU D . n 
D 1 120 HIS 120 120 120 HIS HIS D . n 
D 1 121 GLN 121 121 121 GLN GLN D . n 
D 1 122 PRO 122 122 122 PRO PRO D . n 
D 1 123 SER 123 123 123 SER SER D . n 
D 1 124 THR 124 124 124 THR THR D . n 
D 1 125 TYR 125 125 125 TYR TYR D . n 
D 1 126 ARG 126 126 126 ARG ARG D . n 
D 1 127 VAL 127 127 127 VAL VAL D . n 
D 1 128 THR 128 128 128 THR THR D . n 
D 1 129 LYS 129 129 129 LYS LYS D . n 
D 1 130 HIS 130 130 130 HIS HIS D . n 
D 1 131 VAL 131 131 131 VAL VAL D . n 
D 1 132 THR 132 132 132 THR THR D . n 
D 1 133 LEU 133 133 133 LEU LEU D . n 
D 1 134 ALA 134 134 134 ALA ALA D . n 
D 1 135 PRO 135 135 135 PRO PRO D . n 
D 1 136 GLU 136 136 136 GLU GLU D . n 
D 1 137 ALA 137 137 137 ALA ALA D . n 
D 1 138 SER 138 138 138 SER SER D . n 
D 1 139 GLY 139 139 139 GLY GLY D . n 
D 1 140 ALA 140 140 140 ALA ALA D . n 
D 1 141 PRO 141 141 141 PRO PRO D . n 
D 1 142 PHE 142 142 142 PHE PHE D . n 
D 1 143 ARG 143 143 143 ARG ARG D . n 
D 1 144 TYR 144 144 144 TYR TYR D . n 
D 1 145 GLY 145 145 145 GLY GLY D . n 
D 1 146 VAL 146 146 146 VAL VAL D . n 
D 1 147 SER 147 147 147 SER SER D . n 
D 1 148 LEU 148 148 148 LEU LEU D . n 
D 1 149 TYR 149 149 149 TYR TYR D . n 
D 1 150 SER 150 150 150 SER SER D . n 
D 1 151 TYR 151 151 151 TYR TYR D . n 
D 1 152 MET 152 152 152 MET MET D . n 
D 1 153 SER 153 153 153 SER SER D . n 
D 1 154 ASP 154 154 154 ASP ASP D . n 
D 1 155 TYR 155 155 155 TYR TYR D . n 
D 1 156 GLY 156 156 156 GLY GLY D . n 
D 1 157 THR 157 157 157 THR THR D . n 
D 1 158 VAL 158 158 158 VAL VAL D . n 
D 1 159 MET 159 159 159 MET MET D . n 
D 1 160 ASP 160 160 160 ASP ASP D . n 
D 1 161 LEU 161 161 161 LEU LEU D . n 
D 1 162 GLU 162 162 162 GLU GLU D . n 
D 1 163 THR 163 163 163 THR THR D . n 
D 1 164 ALA 164 164 164 ALA ALA D . n 
D 1 165 MET 165 165 165 MET MET D . n 
D 1 166 ALA 166 166 166 ALA ALA D . n 
D 1 167 SER 167 167 167 SER SER D . n 
D 1 168 ILE 168 168 168 ILE ILE D . n 
D 1 169 ALA 169 169 169 ALA ALA D . n 
D 1 170 ASP 170 170 170 ASP ASP D . n 
D 1 171 LEU 171 171 171 LEU LEU D . n 
D 1 172 GLY 172 172 172 GLY GLY D . n 
D 1 173 ALA 173 173 173 ALA ALA D . n 
D 1 174 THR 174 174 174 THR THR D . n 
D 1 175 GLY 175 175 175 GLY GLY D . n 
D 1 176 ILE 176 176 176 ILE ILE D . n 
D 1 177 GLU 177 177 177 GLU GLU D . n 
D 1 178 ILE 178 178 178 ILE ILE D . n 
D 1 179 LEU 179 179 179 LEU LEU D . n 
D 1 180 GLY 180 180 180 GLY GLY D . n 
D 1 181 GLU 181 181 181 GLU GLU D . n 
D 1 182 ALA 182 182 182 ALA ALA D . n 
D 1 183 HIS 183 183 183 HIS HIS D . n 
D 1 184 VAL 184 184 184 VAL VAL D . n 
D 1 185 PRO 185 185 185 PRO PRO D . n 
D 1 186 ASN 186 186 186 ASN ASN D . n 
D 1 187 TYR 187 187 187 TYR TYR D . n 
D 1 188 PRO 188 188 188 PRO PRO D . n 
D 1 189 ASN 189 189 189 ASN ASN D . n 
D 1 190 PRO 190 190 190 PRO PRO D . n 
D 1 191 SER 191 191 191 SER SER D . n 
D 1 192 ASP 192 192 192 ASP ASP D . n 
D 1 193 GLU 193 193 193 GLU GLU D . n 
D 1 194 TRP 194 194 194 TRP TRP D . n 
D 1 195 VAL 195 195 195 VAL VAL D . n 
D 1 196 GLU 196 196 196 GLU GLU D . n 
D 1 197 GLN 197 197 197 GLN GLN D . n 
D 1 198 TRP 198 198 198 TRP TRP D . n 
D 1 199 PHE 199 199 199 PHE PHE D . n 
D 1 200 ALA 200 200 200 ALA ALA D . n 
D 1 201 LEU 201 201 201 LEU LEU D . n 
D 1 202 LEU 202 202 202 LEU LEU D . n 
D 1 203 SER 203 203 203 SER SER D . n 
D 1 204 THR 204 204 204 THR THR D . n 
D 1 205 TYR 205 205 205 TYR TYR D . n 
D 1 206 GLY 206 206 206 GLY GLY D . n 
D 1 207 LEU 207 207 207 LEU LEU D . n 
D 1 208 GLU 208 208 208 GLU GLU D . n 
D 1 209 PRO 209 209 209 PRO PRO D . n 
D 1 210 THR 210 210 210 THR THR D . n 
D 1 211 ASN 211 211 211 ASN ASN D . n 
D 1 212 MET 212 212 212 MET MET D . n 
D 1 213 GLY 213 213 213 GLY GLY D . n 
D 1 214 SER 214 214 214 SER SER D . n 
D 1 215 TRP 215 215 215 TRP TRP D . n 
D 1 216 ILE 216 216 216 ILE ILE D . n 
D 1 217 ASP 217 217 217 ASP ASP D . n 
D 1 218 THR 218 218 218 THR THR D . n 
D 1 219 ARG 219 219 219 ARG ARG D . n 
D 1 220 LEU 220 220 220 LEU LEU D . n 
D 1 221 HIS 221 221 221 HIS HIS D . n 
D 1 222 SER 222 222 222 SER SER D . n 
D 1 223 SER 223 223 223 SER SER D . n 
D 1 224 GLY 224 224 224 GLY GLY D . n 
D 1 225 PRO 225 225 225 PRO PRO D . n 
D 1 226 ASN 226 226 226 ASN ASN D . n 
D 1 227 GLY 227 227 227 GLY GLY D . n 
D 1 228 ARG 228 228 228 ARG ARG D . n 
D 1 229 ASP 229 229 229 ASP ASP D . n 
D 1 230 MET 230 230 230 MET MET D . n 
D 1 231 THR 231 231 231 THR THR D . n 
D 1 232 VAL 232 232 232 VAL VAL D . n 
D 1 233 GLU 233 233 233 GLU GLU D . n 
D 1 234 GLU 234 234 234 GLU GLU D . n 
D 1 235 GLY 235 235 235 GLY GLY D . n 
D 1 236 ALA 236 236 236 ALA ALA D . n 
D 1 237 ALA 237 237 237 ALA ALA D . n 
D 1 238 ALA 238 238 238 ALA ALA D . n 
D 1 239 LEU 239 239 239 LEU LEU D . n 
D 1 240 GLN 240 240 240 GLN GLN D . n 
D 1 241 ARG 241 241 241 ARG ARG D . n 
D 1 242 ASP 242 242 242 ASP ASP D . n 
D 1 243 LEU 243 243 243 LEU LEU D . n 
D 1 244 ARG 244 244 244 ARG ARG D . n 
D 1 245 LEU 245 245 245 LEU LEU D . n 
D 1 246 ALA 246 246 246 ALA ALA D . n 
D 1 247 LYS 247 247 247 LYS LYS D . n 
D 1 248 ARG 248 248 248 ARG ARG D . n 
D 1 249 LEU 249 249 249 LEU LEU D . n 
D 1 250 GLY 250 250 250 GLY GLY D . n 
D 1 251 PHE 251 251 251 PHE PHE D . n 
D 1 252 ARG 252 252 252 ARG ARG D . n 
D 1 253 PHE 253 253 253 PHE PHE D . n 
D 1 254 VAL 254 254 254 VAL VAL D . n 
D 1 255 ARG 255 255 255 ARG ARG D . n 
D 1 256 PRO 256 256 256 PRO PRO D . n 
D 1 257 LYS 257 257 257 LYS LYS D . n 
D 1 258 ILE 258 258 258 ILE ILE D . n 
D 1 259 GLY 259 259 259 GLY GLY D . n 
D 1 260 VAL 260 260 260 VAL VAL D . n 
D 1 261 VAL 261 261 261 VAL VAL D . n 
D 1 262 SER 262 262 262 SER SER D . n 
D 1 263 SER 263 263 263 SER SER D . n 
D 1 264 ASP 264 264 264 ASP ASP D . n 
D 1 265 LEU 265 265 265 LEU LEU D . n 
D 1 266 ILE 266 266 266 ILE ILE D . n 
D 1 267 PRO 267 267 267 PRO PRO D . n 
D 1 268 HIS 268 268 268 HIS HIS D . n 
D 1 269 PRO 269 269 269 PRO PRO D . n 
D 1 270 ILE 270 270 270 ILE ILE D . n 
D 1 271 TRP 271 271 271 TRP TRP D . n 
D 1 272 THR 272 272 272 THR THR D . n 
D 1 273 GLU 273 273 273 GLU GLU D . n 
D 1 274 VAL 274 274 274 VAL VAL D . n 
D 1 275 VAL 275 275 275 VAL VAL D . n 
D 1 276 GLU 276 276 276 GLU GLU D . n 
D 1 277 ALA 277 277 277 ALA ALA D . n 
D 1 278 SER 278 278 278 SER SER D . n 
D 1 279 LEU 279 279 279 LEU LEU D . n 
D 1 280 PRO 280 280 280 PRO PRO D . n 
D 1 281 LEU 281 281 281 LEU LEU D . n 
D 1 282 ALA 282 282 282 ALA ALA D . n 
D 1 283 GLU 283 283 283 GLU GLU D . n 
D 1 284 GLU 284 284 284 GLU GLU D . n 
D 1 285 LEU 285 285 285 LEU LEU D . n 
D 1 286 ASP 286 286 286 ASP ASP D . n 
D 1 287 VAL 287 287 287 VAL VAL D . n 
D 1 288 ILE 288 288 288 ILE ILE D . n 
D 1 289 ILE 289 289 289 ILE ILE D . n 
D 1 290 CYS 290 290 290 CYS CYS D . n 
D 1 291 PRO 291 291 291 PRO PRO D . n 
D 1 292 GLU 292 292 292 GLU GLU D . n 
D 1 293 ILE 293 293 293 ILE ILE D . n 
D 1 294 HIS 294 294 294 HIS HIS D . n 
D 1 295 SER 295 295 295 SER SER D . n 
D 1 296 PRO 296 296 296 PRO PRO D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 PRO 298 298 298 PRO PRO D . n 
D 1 299 ILE 299 299 299 ILE ILE D . n 
D 1 300 LYS 300 300 300 LYS LYS D . n 
D 1 301 HIS 301 301 301 HIS HIS D . n 
D 1 302 GLU 302 302 302 GLU GLU D . n 
D 1 303 VAL 303 303 303 VAL VAL D . n 
D 1 304 VAL 304 304 304 VAL VAL D . n 
D 1 305 ASP 305 305 305 ASP ASP D . n 
D 1 306 ASP 306 306 306 ASP ASP D . n 
D 1 307 TYR 307 307 307 TYR TYR D . n 
D 1 308 ILE 308 308 308 ILE ILE D . n 
D 1 309 ALA 309 309 309 ALA ALA D . n 
D 1 310 LEU 310 310 310 LEU LEU D . n 
D 1 311 ILE 311 311 311 ILE ILE D . n 
D 1 312 ARG 312 312 312 ARG ARG D . n 
D 1 313 ARG 313 313 313 ARG ARG D . n 
D 1 314 THR 314 314 314 THR THR D . n 
D 1 315 GLY 315 315 315 GLY GLY D . n 
D 1 316 THR 316 316 316 THR THR D . n 
D 1 317 LYS 317 317 317 LYS LYS D . n 
D 1 318 HIS 318 318 318 HIS HIS D . n 
D 1 319 PHE 319 319 319 PHE PHE D . n 
D 1 320 GLY 320 320 320 GLY GLY D . n 
D 1 321 LEU 321 321 321 LEU LEU D . n 
D 1 322 LEU 322 322 322 LEU LEU D . n 
D 1 323 LEU 323 323 323 LEU LEU D . n 
D 1 324 ASP 324 324 324 ASP ASP D . n 
D 1 325 THR 325 325 325 THR THR D . n 
D 1 326 GLY 326 326 326 GLY GLY D . n 
D 1 327 ILE 327 327 327 ILE ILE D . n 
D 1 328 PHE 328 328 328 PHE PHE D . n 
D 1 329 GLN 329 329 329 GLN GLN D . n 
D 1 330 ASP 330 330 330 ASP ASP D . n 
D 1 331 ARG 331 331 331 ARG ARG D . n 
D 1 332 PRO 332 332 332 PRO PRO D . n 
D 1 333 ILE 333 333 333 ILE ILE D . n 
D 1 334 PRO 334 334 334 PRO PRO D . n 
D 1 335 LEU 335 335 335 LEU LEU D . n 
D 1 336 LYS 336 336 336 LYS LYS D . n 
D 1 337 PRO 337 337 337 PRO PRO D . n 
D 1 338 GLY 338 338 338 GLY GLY D . n 
D 1 339 GLU 339 339 339 GLU GLU D . n 
D 1 340 LEU 340 340 340 LEU LEU D . n 
D 1 341 PRO 341 341 341 PRO PRO D . n 
D 1 342 GLY 342 342 342 GLY GLY D . n 
D 1 343 GLN 343 343 343 GLN GLN D . n 
D 1 344 ARG 344 344 344 ARG ARG D . n 
D 1 345 PRO 345 345 345 PRO PRO D . n 
D 1 346 ALA 346 346 346 ALA ALA D . n 
D 1 347 PHE 347 347 347 PHE PHE D . n 
D 1 348 LEU 348 348 348 LEU LEU D . n 
D 1 349 ASP 349 349 349 ASP ASP D . n 
D 1 350 GLY 350 350 350 GLY GLY D . n 
D 1 351 ILE 351 351 351 ILE ILE D . n 
D 1 352 HIS 352 352 352 HIS HIS D . n 
D 1 353 VAL 353 353 353 VAL VAL D . n 
D 1 354 ASP 354 354 354 ASP ASP D . n 
D 1 355 PRO 355 355 355 PRO PRO D . n 
D 1 356 ASN 356 356 356 ASN ASN D . n 
D 1 357 ASP 357 357 357 ASP ASP D . n 
D 1 358 VAL 358 358 358 VAL VAL D . n 
D 1 359 PHE 359 359 359 PHE PHE D . n 
D 1 360 ASP 360 360 360 ASP ASP D . n 
D 1 361 VAL 361 361 361 VAL VAL D . n 
D 1 362 ILE 362 362 362 ILE ILE D . n 
D 1 363 GLU 363 363 363 GLU GLU D . n 
D 1 364 ASN 364 364 364 ASN ASN D . n 
D 1 365 VAL 365 365 365 VAL VAL D . n 
D 1 366 VAL 366 366 366 VAL VAL D . n 
D 1 367 PHE 367 367 367 PHE PHE D . n 
D 1 368 ILE 368 368 368 ILE ILE D . n 
D 1 369 GLN 369 369 369 GLN GLN D . n 
D 1 370 ALA 370 370 370 ALA ALA D . n 
D 1 371 LYS 371 371 371 LYS LYS D . n 
D 1 372 PHE 372 372 372 PHE PHE D . n 
D 1 373 HIS 373 373 373 HIS HIS D . n 
D 1 374 ASP 374 374 374 ASP ASP D . n 
D 1 375 ILE 375 375 375 ILE ILE D . n 
D 1 376 ASP 376 376 376 ASP ASP D . n 
D 1 377 GLU 377 377 377 GLU GLU D . n 
D 1 378 GLU 378 378 378 GLU GLU D . n 
D 1 379 LEU 379 379 379 LEU LEU D . n 
D 1 380 ASP 380 380 380 ASP ASP D . n 
D 1 381 ASP 381 381 381 ASP ASP D . n 
D 1 382 LYS 382 382 382 LYS LYS D . n 
D 1 383 GLN 383 383 383 GLN GLN D . n 
D 1 384 ILE 384 384 384 ILE ILE D . n 
D 1 385 PRO 385 385 385 PRO PRO D . n 
D 1 386 TRP 386 386 386 TRP TRP D . n 
D 1 387 GLU 387 387 387 GLU GLU D . n 
D 1 388 PRO 388 388 388 PRO PRO D . n 
D 1 389 VAL 389 389 389 VAL VAL D . n 
D 1 390 LEU 390 390 390 LEU LEU D . n 
D 1 391 LYS 391 391 391 LYS LYS D . n 
D 1 392 ALA 392 392 392 ALA ALA D . n 
D 1 393 LEU 393 393 393 LEU LEU D . n 
D 1 394 LYS 394 394 394 LYS LYS D . n 
D 1 395 ASP 395 395 395 ASP ASP D . n 
D 1 396 ALA 396 396 396 ALA ALA D . n 
D 1 397 GLY 397 397 397 GLY GLY D . n 
D 1 398 TYR 398 398 398 TYR TYR D . n 
D 1 399 THR 399 399 399 THR THR D . n 
D 1 400 GLY 400 400 400 GLY GLY D . n 
D 1 401 TYR 401 401 401 TYR TYR D . n 
D 1 402 LEU 402 402 402 LEU LEU D . n 
D 1 403 SER 403 403 403 SER SER D . n 
D 1 404 SER 404 404 404 SER SER D . n 
D 1 405 GLU 405 405 405 GLU GLU D . n 
D 1 406 TYR 406 406 406 TYR TYR D . n 
D 1 407 GLU 407 407 407 GLU GLU D . n 
D 1 408 GLY 408 408 408 GLY GLY D . n 
D 1 409 GLU 409 409 409 GLU GLU D . n 
D 1 410 ARG 410 410 410 ARG ARG D . n 
D 1 411 GLU 411 411 411 GLU GLU D . n 
D 1 412 PRO 412 412 412 PRO PRO D . n 
D 1 413 TRP 413 413 413 TRP TRP D . n 
D 1 414 ARG 414 414 414 ARG ARG D . n 
D 1 415 SER 415 415 415 SER SER D . n 
D 1 416 ILE 416 416 416 ILE ILE D . n 
D 1 417 GLU 417 417 417 GLU GLU D . n 
D 1 418 GLN 418 418 418 GLN GLN D . n 
D 1 419 VAL 419 419 419 VAL VAL D . n 
D 1 420 ARG 420 420 420 ARG ARG D . n 
D 1 421 ARG 421 421 421 ARG ARG D . n 
D 1 422 GLN 422 422 422 GLN GLN D . n 
D 1 423 HIS 423 423 423 HIS HIS D . n 
D 1 424 SER 424 424 424 SER SER D . n 
D 1 425 LEU 425 425 425 LEU LEU D . n 
D 1 426 ILE 426 426 426 ILE ILE D . n 
D 1 427 ARG 427 427 427 ARG ARG D . n 
D 1 428 GLN 428 428 428 GLN GLN D . n 
D 1 429 ILE 429 429 429 ILE ILE D . n 
D 1 430 ALA 430 430 430 ALA ALA D . n 
D 1 431 ASP 431 431 431 ASP ASP D . n 
D 1 432 ARG 432 432 432 ARG ARG D . n 
D 1 433 LEU 433 433 433 LEU LEU D . n 
D 1 434 ALA 434 434 434 ALA ALA D . n 
D 1 435 GLU 435 435 435 GLU GLU D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        RB 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   RB 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 RB  1   501 501 RB  RB  A . 
F 2 RB  1   501 501 RB  RB  B . 
G 2 RB  1   501 501 RB  RB  C . 
H 2 RB  1   501 501 RB  RB  D . 
I 3 HOH 1   601 37  HOH HOH A . 
I 3 HOH 2   602 54  HOH HOH A . 
I 3 HOH 3   603 194 HOH HOH A . 
I 3 HOH 4   604 331 HOH HOH A . 
I 3 HOH 5   605 219 HOH HOH A . 
I 3 HOH 6   606 25  HOH HOH A . 
I 3 HOH 7   607 259 HOH HOH A . 
I 3 HOH 8   608 175 HOH HOH A . 
I 3 HOH 9   609 88  HOH HOH A . 
I 3 HOH 10  610 356 HOH HOH A . 
I 3 HOH 11  611 50  HOH HOH A . 
I 3 HOH 12  612 167 HOH HOH A . 
I 3 HOH 13  613 24  HOH HOH A . 
I 3 HOH 14  614 90  HOH HOH A . 
I 3 HOH 15  615 27  HOH HOH A . 
I 3 HOH 16  616 104 HOH HOH A . 
I 3 HOH 17  617 273 HOH HOH A . 
I 3 HOH 18  618 51  HOH HOH A . 
I 3 HOH 19  619 230 HOH HOH A . 
I 3 HOH 20  620 16  HOH HOH A . 
I 3 HOH 21  621 207 HOH HOH A . 
I 3 HOH 22  622 100 HOH HOH A . 
I 3 HOH 23  623 102 HOH HOH A . 
I 3 HOH 24  624 326 HOH HOH A . 
I 3 HOH 25  625 601 HOH HOH A . 
I 3 HOH 26  626 145 HOH HOH A . 
I 3 HOH 27  627 321 HOH HOH A . 
I 3 HOH 28  628 270 HOH HOH A . 
I 3 HOH 29  629 149 HOH HOH A . 
I 3 HOH 30  630 32  HOH HOH A . 
I 3 HOH 31  631 299 HOH HOH A . 
I 3 HOH 32  632 14  HOH HOH A . 
I 3 HOH 33  633 48  HOH HOH A . 
I 3 HOH 34  634 303 HOH HOH A . 
I 3 HOH 35  635 42  HOH HOH A . 
I 3 HOH 36  636 174 HOH HOH A . 
I 3 HOH 37  637 9   HOH HOH A . 
I 3 HOH 38  638 226 HOH HOH A . 
I 3 HOH 39  639 602 HOH HOH A . 
I 3 HOH 40  640 282 HOH HOH A . 
I 3 HOH 41  641 290 HOH HOH A . 
I 3 HOH 42  642 36  HOH HOH A . 
I 3 HOH 43  643 170 HOH HOH A . 
I 3 HOH 44  644 231 HOH HOH A . 
I 3 HOH 45  645 348 HOH HOH A . 
I 3 HOH 46  646 320 HOH HOH A . 
I 3 HOH 47  647 108 HOH HOH A . 
I 3 HOH 48  648 117 HOH HOH A . 
I 3 HOH 49  649 168 HOH HOH A . 
I 3 HOH 50  650 317 HOH HOH A . 
I 3 HOH 51  651 116 HOH HOH A . 
I 3 HOH 52  652 161 HOH HOH A . 
I 3 HOH 53  653 294 HOH HOH A . 
I 3 HOH 54  654 235 HOH HOH A . 
I 3 HOH 55  655 322 HOH HOH A . 
I 3 HOH 56  656 209 HOH HOH A . 
I 3 HOH 57  657 274 HOH HOH A . 
I 3 HOH 58  658 301 HOH HOH A . 
I 3 HOH 59  659 203 HOH HOH A . 
I 3 HOH 60  660 62  HOH HOH A . 
I 3 HOH 61  661 5   HOH HOH A . 
I 3 HOH 62  662 255 HOH HOH A . 
I 3 HOH 63  663 201 HOH HOH A . 
I 3 HOH 64  664 237 HOH HOH A . 
I 3 HOH 65  665 205 HOH HOH A . 
I 3 HOH 66  666 258 HOH HOH A . 
I 3 HOH 67  667 72  HOH HOH A . 
I 3 HOH 68  668 13  HOH HOH A . 
I 3 HOH 69  669 208 HOH HOH A . 
I 3 HOH 70  670 224 HOH HOH A . 
I 3 HOH 71  671 73  HOH HOH A . 
I 3 HOH 72  672 221 HOH HOH A . 
I 3 HOH 73  673 109 HOH HOH A . 
I 3 HOH 74  674 191 HOH HOH A . 
I 3 HOH 75  675 349 HOH HOH A . 
I 3 HOH 76  676 179 HOH HOH A . 
I 3 HOH 77  677 368 HOH HOH A . 
I 3 HOH 78  678 52  HOH HOH A . 
I 3 HOH 79  679 245 HOH HOH A . 
I 3 HOH 80  680 70  HOH HOH A . 
I 3 HOH 81  681 248 HOH HOH A . 
I 3 HOH 82  682 311 HOH HOH A . 
I 3 HOH 83  683 271 HOH HOH A . 
I 3 HOH 84  684 28  HOH HOH A . 
I 3 HOH 85  685 148 HOH HOH A . 
I 3 HOH 86  686 214 HOH HOH A . 
I 3 HOH 87  687 122 HOH HOH A . 
I 3 HOH 88  688 268 HOH HOH A . 
I 3 HOH 89  689 105 HOH HOH A . 
I 3 HOH 90  690 308 HOH HOH A . 
I 3 HOH 91  691 251 HOH HOH A . 
I 3 HOH 92  692 26  HOH HOH A . 
I 3 HOH 93  693 339 HOH HOH A . 
I 3 HOH 94  694 346 HOH HOH A . 
I 3 HOH 95  695 279 HOH HOH A . 
I 3 HOH 96  696 143 HOH HOH A . 
I 3 HOH 97  697 304 HOH HOH A . 
I 3 HOH 98  698 215 HOH HOH A . 
I 3 HOH 99  699 184 HOH HOH A . 
J 3 HOH 1   601 49  HOH HOH B . 
J 3 HOH 2   602 156 HOH HOH B . 
J 3 HOH 3   603 232 HOH HOH B . 
J 3 HOH 4   604 78  HOH HOH B . 
J 3 HOH 5   605 86  HOH HOH B . 
J 3 HOH 6   606 234 HOH HOH B . 
J 3 HOH 7   607 21  HOH HOH B . 
J 3 HOH 8   608 166 HOH HOH B . 
J 3 HOH 9   609 1   HOH HOH B . 
J 3 HOH 10  610 183 HOH HOH B . 
J 3 HOH 11  611 113 HOH HOH B . 
J 3 HOH 12  612 31  HOH HOH B . 
J 3 HOH 13  613 95  HOH HOH B . 
J 3 HOH 14  614 142 HOH HOH B . 
J 3 HOH 15  615 332 HOH HOH B . 
J 3 HOH 16  616 280 HOH HOH B . 
J 3 HOH 17  617 6   HOH HOH B . 
J 3 HOH 18  618 288 HOH HOH B . 
J 3 HOH 19  619 45  HOH HOH B . 
J 3 HOH 20  620 131 HOH HOH B . 
J 3 HOH 21  621 324 HOH HOH B . 
J 3 HOH 22  622 10  HOH HOH B . 
J 3 HOH 23  623 80  HOH HOH B . 
J 3 HOH 24  624 601 HOH HOH B . 
J 3 HOH 25  625 306 HOH HOH B . 
J 3 HOH 26  626 17  HOH HOH B . 
J 3 HOH 27  627 71  HOH HOH B . 
J 3 HOH 28  628 345 HOH HOH B . 
J 3 HOH 29  629 57  HOH HOH B . 
J 3 HOH 30  630 129 HOH HOH B . 
J 3 HOH 31  631 357 HOH HOH B . 
J 3 HOH 32  632 211 HOH HOH B . 
J 3 HOH 33  633 15  HOH HOH B . 
J 3 HOH 34  634 7   HOH HOH B . 
J 3 HOH 35  635 171 HOH HOH B . 
J 3 HOH 36  636 140 HOH HOH B . 
J 3 HOH 37  637 74  HOH HOH B . 
J 3 HOH 38  638 285 HOH HOH B . 
J 3 HOH 39  639 85  HOH HOH B . 
J 3 HOH 40  640 114 HOH HOH B . 
J 3 HOH 41  641 257 HOH HOH B . 
J 3 HOH 42  642 254 HOH HOH B . 
J 3 HOH 43  643 121 HOH HOH B . 
J 3 HOH 44  644 96  HOH HOH B . 
J 3 HOH 45  645 41  HOH HOH B . 
J 3 HOH 46  646 236 HOH HOH B . 
J 3 HOH 47  647 336 HOH HOH B . 
J 3 HOH 48  648 123 HOH HOH B . 
J 3 HOH 49  649 193 HOH HOH B . 
J 3 HOH 50  650 3   HOH HOH B . 
J 3 HOH 51  651 176 HOH HOH B . 
J 3 HOH 52  652 20  HOH HOH B . 
J 3 HOH 53  653 213 HOH HOH B . 
J 3 HOH 54  654 38  HOH HOH B . 
J 3 HOH 55  655 106 HOH HOH B . 
J 3 HOH 56  656 69  HOH HOH B . 
J 3 HOH 57  657 192 HOH HOH B . 
J 3 HOH 58  658 172 HOH HOH B . 
J 3 HOH 59  659 101 HOH HOH B . 
J 3 HOH 60  660 165 HOH HOH B . 
J 3 HOH 61  661 53  HOH HOH B . 
J 3 HOH 62  662 362 HOH HOH B . 
J 3 HOH 63  663 252 HOH HOH B . 
J 3 HOH 64  664 173 HOH HOH B . 
J 3 HOH 65  665 164 HOH HOH B . 
J 3 HOH 66  666 91  HOH HOH B . 
J 3 HOH 67  667 138 HOH HOH B . 
J 3 HOH 68  668 65  HOH HOH B . 
J 3 HOH 69  669 218 HOH HOH B . 
J 3 HOH 70  670 187 HOH HOH B . 
J 3 HOH 71  671 197 HOH HOH B . 
J 3 HOH 72  672 46  HOH HOH B . 
J 3 HOH 73  673 196 HOH HOH B . 
J 3 HOH 74  674 217 HOH HOH B . 
J 3 HOH 75  675 364 HOH HOH B . 
J 3 HOH 76  676 97  HOH HOH B . 
J 3 HOH 77  677 81  HOH HOH B . 
J 3 HOH 78  678 162 HOH HOH B . 
J 3 HOH 79  679 137 HOH HOH B . 
J 3 HOH 80  680 253 HOH HOH B . 
J 3 HOH 81  681 23  HOH HOH B . 
J 3 HOH 82  682 335 HOH HOH B . 
J 3 HOH 83  683 92  HOH HOH B . 
J 3 HOH 84  684 82  HOH HOH B . 
J 3 HOH 85  685 98  HOH HOH B . 
J 3 HOH 86  686 309 HOH HOH B . 
J 3 HOH 87  687 262 HOH HOH B . 
J 3 HOH 88  688 337 HOH HOH B . 
J 3 HOH 89  689 284 HOH HOH B . 
J 3 HOH 90  690 30  HOH HOH B . 
J 3 HOH 91  691 263 HOH HOH B . 
J 3 HOH 92  692 302 HOH HOH B . 
J 3 HOH 93  693 358 HOH HOH B . 
J 3 HOH 94  694 347 HOH HOH B . 
J 3 HOH 95  695 154 HOH HOH B . 
J 3 HOH 96  696 139 HOH HOH B . 
J 3 HOH 97  697 359 HOH HOH B . 
J 3 HOH 98  698 128 HOH HOH B . 
J 3 HOH 99  699 177 HOH HOH B . 
J 3 HOH 100 700 195 HOH HOH B . 
J 3 HOH 101 701 163 HOH HOH B . 
J 3 HOH 102 702 84  HOH HOH B . 
J 3 HOH 103 703 287 HOH HOH B . 
J 3 HOH 104 704 318 HOH HOH B . 
K 3 HOH 1   601 353 HOH HOH C . 
K 3 HOH 2   602 134 HOH HOH C . 
K 3 HOH 3   603 2   HOH HOH C . 
K 3 HOH 4   604 59  HOH HOH C . 
K 3 HOH 5   605 333 HOH HOH C . 
K 3 HOH 6   606 155 HOH HOH C . 
K 3 HOH 7   607 602 HOH HOH C . 
K 3 HOH 8   608 111 HOH HOH C . 
K 3 HOH 9   609 159 HOH HOH C . 
K 3 HOH 10  610 60  HOH HOH C . 
K 3 HOH 11  611 141 HOH HOH C . 
K 3 HOH 12  612 228 HOH HOH C . 
K 3 HOH 13  613 246 HOH HOH C . 
K 3 HOH 14  614 47  HOH HOH C . 
K 3 HOH 15  615 341 HOH HOH C . 
K 3 HOH 16  616 120 HOH HOH C . 
K 3 HOH 17  617 296 HOH HOH C . 
K 3 HOH 18  618 272 HOH HOH C . 
K 3 HOH 19  619 325 HOH HOH C . 
K 3 HOH 20  620 67  HOH HOH C . 
K 3 HOH 21  621 220 HOH HOH C . 
K 3 HOH 22  622 75  HOH HOH C . 
K 3 HOH 23  623 124 HOH HOH C . 
K 3 HOH 24  624 118 HOH HOH C . 
K 3 HOH 25  625 314 HOH HOH C . 
K 3 HOH 26  626 206 HOH HOH C . 
K 3 HOH 27  627 79  HOH HOH C . 
K 3 HOH 28  628 188 HOH HOH C . 
K 3 HOH 29  629 310 HOH HOH C . 
K 3 HOH 30  630 18  HOH HOH C . 
K 3 HOH 31  631 151 HOH HOH C . 
K 3 HOH 32  632 264 HOH HOH C . 
K 3 HOH 33  633 210 HOH HOH C . 
K 3 HOH 34  634 64  HOH HOH C . 
K 3 HOH 35  635 327 HOH HOH C . 
K 3 HOH 36  636 328 HOH HOH C . 
K 3 HOH 37  637 277 HOH HOH C . 
K 3 HOH 38  638 83  HOH HOH C . 
K 3 HOH 39  639 12  HOH HOH C . 
K 3 HOH 40  640 107 HOH HOH C . 
K 3 HOH 41  641 94  HOH HOH C . 
K 3 HOH 42  642 239 HOH HOH C . 
K 3 HOH 43  643 103 HOH HOH C . 
K 3 HOH 44  644 8   HOH HOH C . 
K 3 HOH 45  645 40  HOH HOH C . 
K 3 HOH 46  646 19  HOH HOH C . 
K 3 HOH 47  647 199 HOH HOH C . 
K 3 HOH 48  648 185 HOH HOH C . 
K 3 HOH 49  649 58  HOH HOH C . 
K 3 HOH 50  650 342 HOH HOH C . 
K 3 HOH 51  651 354 HOH HOH C . 
K 3 HOH 52  652 76  HOH HOH C . 
K 3 HOH 53  653 315 HOH HOH C . 
K 3 HOH 54  654 223 HOH HOH C . 
K 3 HOH 55  655 44  HOH HOH C . 
K 3 HOH 56  656 367 HOH HOH C . 
K 3 HOH 57  657 11  HOH HOH C . 
K 3 HOH 58  658 300 HOH HOH C . 
K 3 HOH 59  659 281 HOH HOH C . 
K 3 HOH 60  660 34  HOH HOH C . 
K 3 HOH 61  661 4   HOH HOH C . 
K 3 HOH 62  662 601 HOH HOH C . 
K 3 HOH 63  663 238 HOH HOH C . 
K 3 HOH 64  664 283 HOH HOH C . 
K 3 HOH 65  665 89  HOH HOH C . 
K 3 HOH 66  666 370 HOH HOH C . 
K 3 HOH 67  667 29  HOH HOH C . 
K 3 HOH 68  668 243 HOH HOH C . 
K 3 HOH 69  669 292 HOH HOH C . 
K 3 HOH 70  670 135 HOH HOH C . 
K 3 HOH 71  671 35  HOH HOH C . 
K 3 HOH 72  672 136 HOH HOH C . 
K 3 HOH 73  673 319 HOH HOH C . 
K 3 HOH 74  674 344 HOH HOH C . 
K 3 HOH 75  675 43  HOH HOH C . 
K 3 HOH 76  676 275 HOH HOH C . 
K 3 HOH 77  677 178 HOH HOH C . 
K 3 HOH 78  678 355 HOH HOH C . 
K 3 HOH 79  679 267 HOH HOH C . 
K 3 HOH 80  680 323 HOH HOH C . 
K 3 HOH 81  681 266 HOH HOH C . 
K 3 HOH 82  682 182 HOH HOH C . 
K 3 HOH 83  683 276 HOH HOH C . 
K 3 HOH 84  684 265 HOH HOH C . 
L 3 HOH 1   601 157 HOH HOH D . 
L 3 HOH 2   602 361 HOH HOH D . 
L 3 HOH 3   603 133 HOH HOH D . 
L 3 HOH 4   604 340 HOH HOH D . 
L 3 HOH 5   605 146 HOH HOH D . 
L 3 HOH 6   606 112 HOH HOH D . 
L 3 HOH 7   607 343 HOH HOH D . 
L 3 HOH 8   608 242 HOH HOH D . 
L 3 HOH 9   609 169 HOH HOH D . 
L 3 HOH 10  610 352 HOH HOH D . 
L 3 HOH 11  611 305 HOH HOH D . 
L 3 HOH 12  612 190 HOH HOH D . 
L 3 HOH 13  613 338 HOH HOH D . 
L 3 HOH 14  614 189 HOH HOH D . 
L 3 HOH 15  615 115 HOH HOH D . 
L 3 HOH 16  616 334 HOH HOH D . 
L 3 HOH 17  617 87  HOH HOH D . 
L 3 HOH 18  618 63  HOH HOH D . 
L 3 HOH 19  619 22  HOH HOH D . 
L 3 HOH 20  620 365 HOH HOH D . 
L 3 HOH 21  621 360 HOH HOH D . 
L 3 HOH 22  622 244 HOH HOH D . 
L 3 HOH 23  623 39  HOH HOH D . 
L 3 HOH 24  624 55  HOH HOH D . 
L 3 HOH 25  625 200 HOH HOH D . 
L 3 HOH 26  626 132 HOH HOH D . 
L 3 HOH 27  627 56  HOH HOH D . 
L 3 HOH 28  628 241 HOH HOH D . 
L 3 HOH 29  629 291 HOH HOH D . 
L 3 HOH 30  630 227 HOH HOH D . 
L 3 HOH 31  631 33  HOH HOH D . 
L 3 HOH 32  632 153 HOH HOH D . 
L 3 HOH 33  633 297 HOH HOH D . 
L 3 HOH 34  634 298 HOH HOH D . 
L 3 HOH 35  635 313 HOH HOH D . 
L 3 HOH 36  636 158 HOH HOH D . 
L 3 HOH 37  637 181 HOH HOH D . 
L 3 HOH 38  638 225 HOH HOH D . 
L 3 HOH 39  639 212 HOH HOH D . 
L 3 HOH 40  640 369 HOH HOH D . 
L 3 HOH 41  641 202 HOH HOH D . 
L 3 HOH 42  642 119 HOH HOH D . 
L 3 HOH 43  643 363 HOH HOH D . 
L 3 HOH 44  644 130 HOH HOH D . 
L 3 HOH 45  645 61  HOH HOH D . 
L 3 HOH 46  646 77  HOH HOH D . 
L 3 HOH 47  647 180 HOH HOH D . 
L 3 HOH 48  648 160 HOH HOH D . 
L 3 HOH 49  649 125 HOH HOH D . 
L 3 HOH 50  650 330 HOH HOH D . 
L 3 HOH 51  651 126 HOH HOH D . 
L 3 HOH 52  652 127 HOH HOH D . 
L 3 HOH 53  653 204 HOH HOH D . 
L 3 HOH 54  654 68  HOH HOH D . 
L 3 HOH 55  655 144 HOH HOH D . 
L 3 HOH 56  656 295 HOH HOH D . 
L 3 HOH 57  657 278 HOH HOH D . 
L 3 HOH 58  658 229 HOH HOH D . 
L 3 HOH 59  659 249 HOH HOH D . 
L 3 HOH 60  660 110 HOH HOH D . 
L 3 HOH 61  661 256 HOH HOH D . 
L 3 HOH 62  662 66  HOH HOH D . 
L 3 HOH 63  663 261 HOH HOH D . 
L 3 HOH 64  664 99  HOH HOH D . 
L 3 HOH 65  665 289 HOH HOH D . 
L 3 HOH 66  666 312 HOH HOH D . 
L 3 HOH 67  667 329 HOH HOH D . 
L 3 HOH 68  668 247 HOH HOH D . 
L 3 HOH 69  669 240 HOH HOH D . 
L 3 HOH 70  670 147 HOH HOH D . 
L 3 HOH 71  671 601 HOH HOH D . 
L 3 HOH 72  672 198 HOH HOH D . 
L 3 HOH 73  673 150 HOH HOH D . 
L 3 HOH 74  674 316 HOH HOH D . 
L 3 HOH 75  675 152 HOH HOH D . 
L 3 HOH 76  676 93  HOH HOH D . 
L 3 HOH 77  677 366 HOH HOH D . 
L 3 HOH 78  678 286 HOH HOH D . 
L 3 HOH 79  679 307 HOH HOH D . 
L 3 HOH 80  680 269 HOH HOH D . 
L 3 HOH 81  681 293 HOH HOH D . 
L 3 HOH 82  682 222 HOH HOH D . 
L 3 HOH 83  683 186 HOH HOH D . 
L 3 HOH 84  684 260 HOH HOH D . 
L 3 HOH 85  685 350 HOH HOH D . 
L 3 HOH 86  686 351 HOH HOH D . 
L 3 HOH 87  687 233 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 4 
# 
_cell.angle_alpha                  90.17 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   94.39 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  106.58 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8QRZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     78.220 
_cell.length_a_esd                 ? 
_cell.length_b                     80.410 
_cell.length_b_esd                 ? 
_cell.length_c                     82.960 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8QRZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8QRZ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.59 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.5 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'0.1 M PIPES pH 7.0, 25% (w/v) PEGSH (PEG SMEAR HIGH), 0.1 M rubidium(I) chloride, 0.1 M magnesium(II) formate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE CdTe 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.61992 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.61992 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          31.55 
_reflns.entry_id                                       8QRZ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.0 
_reflns.d_resolution_low                               47.29 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     128896 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.995 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.111 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.0 
_reflns_shell.d_res_low                                     2.1 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             17550 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.9 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.458 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.034 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8QRZ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.00 
_refine.ls_d_res_low                             39.91 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     128873 
_refine.ls_number_reflns_R_free                  2011 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.77 
_refine.ls_percent_reflns_R_free                 1.56 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2373 
_refine.ls_R_factor_R_free                       0.2899 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2365 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.95 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            'Random selection' 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 33.21 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.36 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        13760 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         4 
_refine_hist.number_atoms_solvent             374 
_refine_hist.number_atoms_total               14138 
_refine_hist.d_res_high                       2.00 
_refine_hist.d_res_low                        39.91 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008 ? 14159 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.984 ? 19300 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 6.177 ? 1920  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.056 ? 2108  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.011 ? 2541  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.00 2.05  . . 154 9015 99.00 . . . . 0.3483 . . . . . . . . . . . 0.3868 
'X-RAY DIFFRACTION' 2.05 2.11  . . 141 9120 99.00 . . . . 0.3331 . . . . . . . . . . . 0.3923 
'X-RAY DIFFRACTION' 2.11 2.17  . . 140 9037 99.00 . . . . 0.3127 . . . . . . . . . . . 0.3565 
'X-RAY DIFFRACTION' 2.17 2.24  . . 140 9143 99.00 . . . . 0.3061 . . . . . . . . . . . 0.3849 
'X-RAY DIFFRACTION' 2.24 2.32  . . 145 9027 99.00 . . . . 0.2918 . . . . . . . . . . . 0.3314 
'X-RAY DIFFRACTION' 2.32 2.41  . . 147 9052 99.00 . . . . 0.2804 . . . . . . . . . . . 0.3538 
'X-RAY DIFFRACTION' 2.41 2.52  . . 144 9129 99.00 . . . . 0.2711 . . . . . . . . . . . 0.3281 
'X-RAY DIFFRACTION' 2.52 2.65  . . 123 9037 99.00 . . . . 0.2645 . . . . . . . . . . . 0.3334 
'X-RAY DIFFRACTION' 2.65 2.82  . . 156 9093 99.00 . . . . 0.2625 . . . . . . . . . . . 0.3190 
'X-RAY DIFFRACTION' 2.82 3.04  . . 135 9080 99.00 . . . . 0.2609 . . . . . . . . . . . 0.3063 
'X-RAY DIFFRACTION' 3.04 3.34  . . 144 9078 99.00 . . . . 0.2423 . . . . . . . . . . . 0.3178 
'X-RAY DIFFRACTION' 3.34 3.82  . . 147 8994 98.00 . . . . 0.2162 . . . . . . . . . . . 0.2782 
'X-RAY DIFFRACTION' 3.82 4.82  . . 153 9048 99.00 . . . . 0.1743 . . . . . . . . . . . 0.2191 
'X-RAY DIFFRACTION' 4.82 39.91 . . 142 9009 98.00 . . . . 0.1929 . . . . . . . . . . . 0.2248 
# 
_struct.entry_id                     8QRZ 
_struct.title                        'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8QRZ 
_struct_keywords.text            
;bacterial C-glucosyl deglycosidase, C-C bond cleavage, C-glucosyl flavonoids, Microbacterium testaceum NS220, plant endosymbiont, N-terminal DUF6379 beta-sandwich domain, C-terminal TIM barrel domain, homodimer, LYASE
;
_struct_keywords.pdbx_keywords   LYASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A147EV52_MICTE 
_struct_ref.pdbx_db_accession          A0A147EV52 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8QRZ A 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
2 1 8QRZ B 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
3 1 8QRZ C 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
4 1 8QRZ D 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8QRZ ALA A 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 1 
1 8QRZ GLU A 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 2 
2 8QRZ ALA B 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 3 
2 8QRZ GLU B 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 4 
3 8QRZ ALA C 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 5 
3 8QRZ GLU C 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 6 
4 8QRZ ALA D 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 7 
4 8QRZ GLU D 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 8 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6010  ? 
1 MORE         -32   ? 
1 'SSA (A^2)'  32820 ? 
2 'ABSA (A^2)' 5960  ? 
2 MORE         -38   ? 
2 'SSA (A^2)'  32960 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,I,J 
2 1 C,D,G,H,K,L 
# 
loop_
_pdbx_struct_assembly_auth_evidence.id 
_pdbx_struct_assembly_auth_evidence.assembly_id 
_pdbx_struct_assembly_auth_evidence.experimental_support 
_pdbx_struct_assembly_auth_evidence.details 
1 1 'gel filtration' 'Homodimer confirmed by gel filtration, cryo-EM structure determination and crystal structure' 
2 2 'gel filtration' 'Homodimer confirmed by gel filtration, cryo-EM structure determination and crystal structure' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 70  ? GLY A 77  ? THR A 70  GLY A 77  1 ? 8  
HELX_P HELX_P2  AA2 PRO A 117 ? GLN A 121 ? PRO A 117 GLN A 121 5 ? 5  
HELX_P HELX_P3  AA3 TYR A 149 ? MET A 152 ? TYR A 149 MET A 152 5 ? 4  
HELX_P HELX_P4  AA4 ASP A 160 ? LEU A 171 ? ASP A 160 LEU A 171 1 ? 12 
HELX_P HELX_P5  AA5 GLY A 180 ? VAL A 184 ? GLY A 180 VAL A 184 1 ? 5  
HELX_P HELX_P6  AA6 SER A 191 ? GLY A 206 ? SER A 191 GLY A 206 1 ? 16 
HELX_P HELX_P7  AA7 THR A 231 ? LEU A 249 ? THR A 231 LEU A 249 1 ? 19 
HELX_P HELX_P8  AA8 ILE A 270 ? ALA A 277 ? ILE A 270 ALA A 277 1 ? 8  
HELX_P HELX_P9  AA9 SER A 278 ? ASP A 286 ? SER A 278 ASP A 286 1 ? 9  
HELX_P HELX_P10 AB1 HIS A 301 ? GLY A 315 ? HIS A 301 GLY A 315 1 ? 15 
HELX_P HELX_P11 AB2 GLY A 326 ? GLN A 329 ? GLY A 326 GLN A 329 5 ? 4  
HELX_P HELX_P12 AB3 PRO A 345 ? GLY A 350 ? PRO A 345 GLY A 350 5 ? 6  
HELX_P HELX_P13 AB4 ASP A 354 ? PHE A 359 ? ASP A 354 PHE A 359 5 ? 6  
HELX_P HELX_P14 AB5 VAL A 361 ? GLU A 363 ? VAL A 361 GLU A 363 5 ? 3  
HELX_P HELX_P15 AB6 PRO A 385 ? ALA A 396 ? PRO A 385 ALA A 396 1 ? 12 
HELX_P HELX_P16 AB7 TRP A 413 ? ALA A 434 ? TRP A 413 ALA A 434 1 ? 22 
HELX_P HELX_P17 AB8 THR B 70  ? GLY B 77  ? THR B 70  GLY B 77  1 ? 8  
HELX_P HELX_P18 AB9 PRO B 117 ? GLN B 121 ? PRO B 117 GLN B 121 5 ? 5  
HELX_P HELX_P19 AC1 TYR B 149 ? MET B 152 ? TYR B 149 MET B 152 5 ? 4  
HELX_P HELX_P20 AC2 ASP B 160 ? LEU B 171 ? ASP B 160 LEU B 171 1 ? 12 
HELX_P HELX_P21 AC3 GLY B 180 ? VAL B 184 ? GLY B 180 VAL B 184 1 ? 5  
HELX_P HELX_P22 AC4 SER B 191 ? GLY B 206 ? SER B 191 GLY B 206 1 ? 16 
HELX_P HELX_P23 AC5 THR B 231 ? GLY B 250 ? THR B 231 GLY B 250 1 ? 20 
HELX_P HELX_P24 AC6 ILE B 270 ? ALA B 277 ? ILE B 270 ALA B 277 1 ? 8  
HELX_P HELX_P25 AC7 SER B 278 ? ASP B 286 ? SER B 278 ASP B 286 1 ? 9  
HELX_P HELX_P26 AC8 HIS B 301 ? GLY B 315 ? HIS B 301 GLY B 315 1 ? 15 
HELX_P HELX_P27 AC9 GLY B 326 ? GLN B 329 ? GLY B 326 GLN B 329 5 ? 4  
HELX_P HELX_P28 AD1 ALA B 346 ? GLY B 350 ? ALA B 346 GLY B 350 5 ? 5  
HELX_P HELX_P29 AD2 ASP B 354 ? PHE B 359 ? ASP B 354 PHE B 359 5 ? 6  
HELX_P HELX_P30 AD3 VAL B 361 ? GLU B 363 ? VAL B 361 GLU B 363 5 ? 3  
HELX_P HELX_P31 AD4 PRO B 385 ? ALA B 396 ? PRO B 385 ALA B 396 1 ? 12 
HELX_P HELX_P32 AD5 TRP B 413 ? ALA B 434 ? TRP B 413 ALA B 434 1 ? 22 
HELX_P HELX_P33 AD6 THR C 70  ? GLY C 77  ? THR C 70  GLY C 77  1 ? 8  
HELX_P HELX_P34 AD7 PRO C 117 ? GLN C 121 ? PRO C 117 GLN C 121 5 ? 5  
HELX_P HELX_P35 AD8 TYR C 149 ? MET C 152 ? TYR C 149 MET C 152 5 ? 4  
HELX_P HELX_P36 AD9 ASP C 160 ? ASP C 170 ? ASP C 160 ASP C 170 1 ? 11 
HELX_P HELX_P37 AE1 GLY C 180 ? VAL C 184 ? GLY C 180 VAL C 184 1 ? 5  
HELX_P HELX_P38 AE2 SER C 191 ? GLY C 206 ? SER C 191 GLY C 206 1 ? 16 
HELX_P HELX_P39 AE3 THR C 231 ? LEU C 249 ? THR C 231 LEU C 249 1 ? 19 
HELX_P HELX_P40 AE4 ILE C 270 ? ALA C 277 ? ILE C 270 ALA C 277 1 ? 8  
HELX_P HELX_P41 AE5 SER C 278 ? ASP C 286 ? SER C 278 ASP C 286 1 ? 9  
HELX_P HELX_P42 AE6 HIS C 301 ? GLY C 315 ? HIS C 301 GLY C 315 1 ? 15 
HELX_P HELX_P43 AE7 GLY C 326 ? GLN C 329 ? GLY C 326 GLN C 329 5 ? 4  
HELX_P HELX_P44 AE8 PRO C 345 ? GLY C 350 ? PRO C 345 GLY C 350 5 ? 6  
HELX_P HELX_P45 AE9 ASP C 354 ? ASN C 356 ? ASP C 354 ASN C 356 5 ? 3  
HELX_P HELX_P46 AF1 ASP C 357 ? ILE C 362 ? ASP C 357 ILE C 362 1 ? 6  
HELX_P HELX_P47 AF2 PRO C 385 ? ALA C 396 ? PRO C 385 ALA C 396 1 ? 12 
HELX_P HELX_P48 AF3 TRP C 413 ? GLU C 435 ? TRP C 413 GLU C 435 1 ? 23 
HELX_P HELX_P49 AF4 THR D 70  ? GLY D 77  ? THR D 70  GLY D 77  1 ? 8  
HELX_P HELX_P50 AF5 PRO D 117 ? GLN D 121 ? PRO D 117 GLN D 121 5 ? 5  
HELX_P HELX_P51 AF6 TYR D 149 ? MET D 152 ? TYR D 149 MET D 152 5 ? 4  
HELX_P HELX_P52 AF7 ASP D 160 ? ASP D 170 ? ASP D 160 ASP D 170 1 ? 11 
HELX_P HELX_P53 AF8 GLY D 180 ? VAL D 184 ? GLY D 180 VAL D 184 1 ? 5  
HELX_P HELX_P54 AF9 SER D 191 ? GLY D 206 ? SER D 191 GLY D 206 1 ? 16 
HELX_P HELX_P55 AG1 THR D 231 ? LEU D 249 ? THR D 231 LEU D 249 1 ? 19 
HELX_P HELX_P56 AG2 ILE D 270 ? ASP D 286 ? ILE D 270 ASP D 286 1 ? 17 
HELX_P HELX_P57 AG3 HIS D 301 ? GLY D 315 ? HIS D 301 GLY D 315 1 ? 15 
HELX_P HELX_P58 AG4 GLY D 326 ? GLN D 329 ? GLY D 326 GLN D 329 5 ? 4  
HELX_P HELX_P59 AG5 LEU D 340 ? ARG D 344 ? LEU D 340 ARG D 344 5 ? 5  
HELX_P HELX_P60 AG6 PRO D 345 ? GLY D 350 ? PRO D 345 GLY D 350 5 ? 6  
HELX_P HELX_P61 AG7 ASP D 354 ? ASN D 356 ? ASP D 354 ASN D 356 5 ? 3  
HELX_P HELX_P62 AG8 ASP D 357 ? ILE D 362 ? ASP D 357 ILE D 362 1 ? 6  
HELX_P HELX_P63 AG9 PRO D 385 ? ALA D 396 ? PRO D 385 ALA D 396 1 ? 12 
HELX_P HELX_P64 AH1 TRP D 413 ? GLU D 435 ? TRP D 413 GLU D 435 1 ? 23 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A GLU 405 OE2 ? ? ? 1_555 E RB . RB ? ? A GLU 405 A RB 501 1_555 ? ? ? ? ? ? ? 3.139 ? ? 
metalc2 metalc ? ? D LYS 371 NZ  ? ? ? 1_555 H RB . RB ? ? D LYS 371 D RB 501 1_555 ? ? ? ? ? ? ? 3.046 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  GLN 121 A . ? GLN 121 A PRO 122 A ? PRO 122 A 1 1.40  
2  ALA 140 A . ? ALA 140 A PRO 141 A ? PRO 141 A 1 1.52  
3  TYR 187 A . ? TYR 187 A PRO 188 A ? PRO 188 A 1 2.64  
4  SER 295 A . ? SER 295 A PRO 296 A ? PRO 296 A 1 9.77  
5  GLN 121 B . ? GLN 121 B PRO 122 B ? PRO 122 B 1 1.42  
6  ALA 140 B . ? ALA 140 B PRO 141 B ? PRO 141 B 1 4.07  
7  TYR 187 B . ? TYR 187 B PRO 188 B ? PRO 188 B 1 6.91  
8  SER 295 B . ? SER 295 B PRO 296 B ? PRO 296 B 1 11.16 
9  GLN 121 C . ? GLN 121 C PRO 122 C ? PRO 122 C 1 7.99  
10 ALA 140 C . ? ALA 140 C PRO 141 C ? PRO 141 C 1 6.05  
11 TYR 187 C . ? TYR 187 C PRO 188 C ? PRO 188 C 1 3.20  
12 SER 295 C . ? SER 295 C PRO 296 C ? PRO 296 C 1 8.47  
13 GLN 121 D . ? GLN 121 D PRO 122 D ? PRO 122 D 1 1.67  
14 ALA 140 D . ? ALA 140 D PRO 141 D ? PRO 141 D 1 4.86  
15 TYR 187 D . ? TYR 187 D PRO 188 D ? PRO 188 D 1 5.83  
16 SER 295 D . ? SER 295 D PRO 296 D ? PRO 296 D 1 6.86  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 9 ? 
AA5 ? 5 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 9 ? 
AA9 ? 5 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 9 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
AB6 ? 4 ? 
AB7 ? 9 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
AA4 6 7 ? parallel      
AA4 7 8 ? parallel      
AA4 8 9 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA8 7 8 ? parallel      
AA8 8 9 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? parallel      
AB3 3 4 ? parallel      
AB3 4 5 ? parallel      
AB3 5 6 ? parallel      
AB3 6 7 ? parallel      
AB3 7 8 ? parallel      
AB3 8 9 ? parallel      
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB7 3 4 ? parallel      
AB7 4 5 ? parallel      
AB7 5 6 ? parallel      
AB7 6 7 ? parallel      
AB7 7 8 ? parallel      
AB7 8 9 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 14  ? GLU A 18  ? ARG A 14  GLU A 18  
AA1 2 GLU A 21  ? VAL A 29  ? GLU A 21  VAL A 29  
AA1 3 ALA A 88  ? PRO A 93  ? ALA A 88  PRO A 93  
AA1 4 LEU A 61  ? LEU A 64  ? LEU A 61  LEU A 64  
AA1 5 GLN A 67  ? TYR A 69  ? GLN A 67  TYR A 69  
AA2 1 MET A 37  ? ALA A 38  ? MET A 37  ALA A 38  
AA2 2 ARG A 81  ? TRP A 82  ? ARG A 81  TRP A 82  
AA3 1 VAL A 53  ? VAL A 55  ? VAL A 53  VAL A 55  
AA3 2 ILE A 42  ? ILE A 49  ? ILE A 42  ILE A 49  
AA3 3 VAL A 102 ? LEU A 111 ? VAL A 102 LEU A 111 
AA3 4 SER A 123 ? THR A 132 ? SER A 123 THR A 132 
AA4 1 ILE A 288 ? ILE A 289 ? ILE A 288 ILE A 289 
AA4 2 PHE A 253 ? ILE A 258 ? PHE A 253 ILE A 258 
AA4 3 GLU A 208 ? ILE A 216 ? GLU A 208 ILE A 216 
AA4 4 GLY A 175 ? LEU A 179 ? GLY A 175 LEU A 179 
AA4 5 ARG A 143 ? SER A 147 ? ARG A 143 SER A 147 
AA4 6 TYR A 401 ? TYR A 406 ? TYR A 401 TYR A 406 
AA4 7 VAL A 365 ? PHE A 372 ? VAL A 365 PHE A 372 
AA4 8 LEU A 321 ? ASP A 324 ? LEU A 321 ASP A 324 
AA4 9 GLU A 292 ? ILE A 293 ? GLU A 292 ILE A 293 
AA5 1 ARG B 14  ? GLU B 18  ? ARG B 14  GLU B 18  
AA5 2 GLU B 21  ? VAL B 29  ? GLU B 21  VAL B 29  
AA5 3 ALA B 88  ? PRO B 93  ? ALA B 88  PRO B 93  
AA5 4 LEU B 61  ? LEU B 64  ? LEU B 61  LEU B 64  
AA5 5 GLN B 67  ? TYR B 69  ? GLN B 67  TYR B 69  
AA6 1 MET B 37  ? ALA B 38  ? MET B 37  ALA B 38  
AA6 2 ARG B 81  ? TRP B 82  ? ARG B 81  TRP B 82  
AA7 1 VAL B 53  ? VAL B 55  ? VAL B 53  VAL B 55  
AA7 2 ILE B 42  ? ILE B 49  ? ILE B 42  ILE B 49  
AA7 3 VAL B 102 ? LEU B 111 ? VAL B 102 LEU B 111 
AA7 4 SER B 123 ? THR B 132 ? SER B 123 THR B 132 
AA8 1 ILE B 288 ? ILE B 289 ? ILE B 288 ILE B 289 
AA8 2 PHE B 253 ? ILE B 258 ? PHE B 253 ILE B 258 
AA8 3 GLU B 208 ? ILE B 216 ? GLU B 208 ILE B 216 
AA8 4 GLY B 175 ? LEU B 179 ? GLY B 175 LEU B 179 
AA8 5 ARG B 143 ? SER B 147 ? ARG B 143 SER B 147 
AA8 6 TYR B 401 ? TYR B 406 ? TYR B 401 TYR B 406 
AA8 7 VAL B 365 ? PHE B 372 ? VAL B 365 PHE B 372 
AA8 8 LEU B 321 ? ASP B 324 ? LEU B 321 ASP B 324 
AA8 9 GLU B 292 ? ILE B 293 ? GLU B 292 ILE B 293 
AA9 1 ARG C 14  ? GLU C 18  ? ARG C 14  GLU C 18  
AA9 2 GLU C 21  ? VAL C 29  ? GLU C 21  VAL C 29  
AA9 3 ALA C 88  ? PRO C 93  ? ALA C 88  PRO C 93  
AA9 4 LEU C 61  ? LEU C 64  ? LEU C 61  LEU C 64  
AA9 5 GLN C 67  ? TYR C 69  ? GLN C 67  TYR C 69  
AB1 1 MET C 37  ? ALA C 38  ? MET C 37  ALA C 38  
AB1 2 ARG C 81  ? TRP C 82  ? ARG C 81  TRP C 82  
AB2 1 VAL C 53  ? VAL C 55  ? VAL C 53  VAL C 55  
AB2 2 ILE C 42  ? ILE C 49  ? ILE C 42  ILE C 49  
AB2 3 VAL C 102 ? LEU C 111 ? VAL C 102 LEU C 111 
AB2 4 SER C 123 ? THR C 132 ? SER C 123 THR C 132 
AB3 1 ILE C 288 ? ILE C 289 ? ILE C 288 ILE C 289 
AB3 2 PHE C 253 ? ILE C 258 ? PHE C 253 ILE C 258 
AB3 3 GLU C 208 ? ILE C 216 ? GLU C 208 ILE C 216 
AB3 4 GLY C 175 ? LEU C 179 ? GLY C 175 LEU C 179 
AB3 5 ARG C 143 ? SER C 147 ? ARG C 143 SER C 147 
AB3 6 TYR C 401 ? TYR C 406 ? TYR C 401 TYR C 406 
AB3 7 VAL C 365 ? PHE C 372 ? VAL C 365 PHE C 372 
AB3 8 LEU C 321 ? ASP C 324 ? LEU C 321 ASP C 324 
AB3 9 GLU C 292 ? ILE C 293 ? GLU C 292 ILE C 293 
AB4 1 ARG D 14  ? GLU D 18  ? ARG D 14  GLU D 18  
AB4 2 GLU D 21  ? VAL D 29  ? GLU D 21  VAL D 29  
AB4 3 ALA D 88  ? PRO D 93  ? ALA D 88  PRO D 93  
AB4 4 LEU D 61  ? LEU D 64  ? LEU D 61  LEU D 64  
AB4 5 GLN D 67  ? TYR D 69  ? GLN D 67  TYR D 69  
AB5 1 MET D 37  ? ALA D 38  ? MET D 37  ALA D 38  
AB5 2 ARG D 81  ? TRP D 82  ? ARG D 81  TRP D 82  
AB6 1 VAL D 53  ? VAL D 55  ? VAL D 53  VAL D 55  
AB6 2 ILE D 42  ? ILE D 49  ? ILE D 42  ILE D 49  
AB6 3 VAL D 102 ? LEU D 111 ? VAL D 102 LEU D 111 
AB6 4 SER D 123 ? THR D 132 ? SER D 123 THR D 132 
AB7 1 ILE D 288 ? ILE D 289 ? ILE D 288 ILE D 289 
AB7 2 PHE D 253 ? ILE D 258 ? PHE D 253 ILE D 258 
AB7 3 GLU D 208 ? ILE D 216 ? GLU D 208 ILE D 216 
AB7 4 GLY D 175 ? LEU D 179 ? GLY D 175 LEU D 179 
AB7 5 ARG D 143 ? SER D 147 ? ARG D 143 SER D 147 
AB7 6 TYR D 401 ? TYR D 406 ? TYR D 401 TYR D 406 
AB7 7 VAL D 365 ? PHE D 372 ? VAL D 365 PHE D 372 
AB7 8 LEU D 321 ? ASP D 324 ? LEU D 321 ASP D 324 
AB7 9 GLU D 292 ? ILE D 293 ? GLU D 292 ILE D 293 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 16  ? N VAL A 16  O GLY A 24  ? O GLY A 24  
AA1 2 3 N PHE A 25  ? N PHE A 25  O VAL A 92  ? O VAL A 92  
AA1 3 4 O ILE A 89  ? O ILE A 89  N THR A 63  ? N THR A 63  
AA1 4 5 N TRP A 62  ? N TRP A 62  O TYR A 69  ? O TYR A 69  
AA2 1 2 N MET A 37  ? N MET A 37  O TRP A 82  ? O TRP A 82  
AA3 1 2 O VAL A 53  ? O VAL A 53  N ILE A 49  ? N ILE A 49  
AA3 2 3 N ARG A 48  ? N ARG A 48  O SER A 106 ? O SER A 106 
AA3 3 4 N LEU A 111 ? N LEU A 111 O SER A 123 ? O SER A 123 
AA4 1 2 O ILE A 288 ? O ILE A 288 N VAL A 254 ? N VAL A 254 
AA4 2 3 O LYS A 257 ? O LYS A 257 N ILE A 216 ? N ILE A 216 
AA4 3 4 O GLY A 213 ? O GLY A 213 N ILE A 178 ? N ILE A 178 
AA4 4 5 O GLU A 177 ? O GLU A 177 N VAL A 146 ? N VAL A 146 
AA4 5 6 N ARG A 143 ? N ARG A 143 O LEU A 402 ? O LEU A 402 
AA4 6 7 O SER A 403 ? O SER A 403 N ILE A 368 ? N ILE A 368 
AA4 7 8 O GLN A 369 ? O GLN A 369 N LEU A 323 ? N LEU A 323 
AA4 8 9 O LEU A 322 ? O LEU A 322 N ILE A 293 ? N ILE A 293 
AA5 1 2 N VAL B 16  ? N VAL B 16  O GLY B 24  ? O GLY B 24  
AA5 2 3 N PHE B 25  ? N PHE B 25  O VAL B 92  ? O VAL B 92  
AA5 3 4 O PHE B 91  ? O PHE B 91  N LEU B 61  ? N LEU B 61  
AA5 4 5 N TRP B 62  ? N TRP B 62  O TYR B 69  ? O TYR B 69  
AA6 1 2 N MET B 37  ? N MET B 37  O TRP B 82  ? O TRP B 82  
AA7 1 2 O VAL B 55  ? O VAL B 55  N VAL B 47  ? N VAL B 47  
AA7 2 3 N GLY B 46  ? N GLY B 46  O GLU B 108 ? O GLU B 108 
AA7 3 4 N LEU B 105 ? N LEU B 105 O LYS B 129 ? O LYS B 129 
AA8 1 2 O ILE B 288 ? O ILE B 288 N VAL B 254 ? N VAL B 254 
AA8 2 3 O LYS B 257 ? O LYS B 257 N ILE B 216 ? N ILE B 216 
AA8 3 4 O GLY B 213 ? O GLY B 213 N ILE B 178 ? N ILE B 178 
AA8 4 5 O GLU B 177 ? O GLU B 177 N VAL B 146 ? N VAL B 146 
AA8 5 6 N SER B 147 ? N SER B 147 O SER B 404 ? O SER B 404 
AA8 6 7 O SER B 403 ? O SER B 403 N ILE B 368 ? N ILE B 368 
AA8 7 8 O VAL B 366 ? O VAL B 366 N LEU B 321 ? N LEU B 321 
AA8 8 9 O LEU B 322 ? O LEU B 322 N ILE B 293 ? N ILE B 293 
AA9 1 2 N VAL C 16  ? N VAL C 16  O GLY C 24  ? O GLY C 24  
AA9 2 3 N PHE C 27  ? N PHE C 27  O ILE C 90  ? O ILE C 90  
AA9 3 4 O PHE C 91  ? O PHE C 91  N LEU C 61  ? N LEU C 61  
AA9 4 5 N TRP C 62  ? N TRP C 62  O TYR C 69  ? O TYR C 69  
AB1 1 2 N MET C 37  ? N MET C 37  O TRP C 82  ? O TRP C 82  
AB2 1 2 O VAL C 53  ? O VAL C 53  N ILE C 49  ? N ILE C 49  
AB2 2 3 N ARG C 48  ? N ARG C 48  O SER C 106 ? O SER C 106 
AB2 3 4 N LEU C 105 ? N LEU C 105 O LYS C 129 ? O LYS C 129 
AB3 1 2 O ILE C 288 ? O ILE C 288 N VAL C 254 ? N VAL C 254 
AB3 2 3 O LYS C 257 ? O LYS C 257 N SER C 214 ? N SER C 214 
AB3 3 4 O GLY C 213 ? O GLY C 213 N ILE C 178 ? N ILE C 178 
AB3 4 5 O GLU C 177 ? O GLU C 177 N VAL C 146 ? N VAL C 146 
AB3 5 6 N ARG C 143 ? N ARG C 143 O LEU C 402 ? O LEU C 402 
AB3 6 7 O SER C 403 ? O SER C 403 N ILE C 368 ? N ILE C 368 
AB3 7 8 O GLN C 369 ? O GLN C 369 N LEU C 323 ? N LEU C 323 
AB3 8 9 O LEU C 322 ? O LEU C 322 N ILE C 293 ? N ILE C 293 
AB4 1 2 N VAL D 16  ? N VAL D 16  O GLY D 24  ? O GLY D 24  
AB4 2 3 N PHE D 25  ? N PHE D 25  O VAL D 92  ? O VAL D 92  
AB4 3 4 O PHE D 91  ? O PHE D 91  N LEU D 61  ? N LEU D 61  
AB4 4 5 N TRP D 62  ? N TRP D 62  O TYR D 69  ? O TYR D 69  
AB5 1 2 N MET D 37  ? N MET D 37  O TRP D 82  ? O TRP D 82  
AB6 1 2 N VAL D 53  ? N VAL D 53  O ILE D 49  ? O ILE D 49  
AB6 2 3 N ASP D 43  ? N ASP D 43  O ARG D 110 ? O ARG D 110 
AB6 3 4 N LEU D 105 ? N LEU D 105 O LYS D 129 ? O LYS D 129 
AB7 1 2 O ILE D 288 ? O ILE D 288 N VAL D 254 ? N VAL D 254 
AB7 2 3 O LYS D 257 ? O LYS D 257 N SER D 214 ? N SER D 214 
AB7 3 4 O GLY D 213 ? O GLY D 213 N ILE D 178 ? N ILE D 178 
AB7 4 5 O GLU D 177 ? O GLU D 177 N VAL D 146 ? N VAL D 146 
AB7 5 6 N SER D 147 ? N SER D 147 O SER D 404 ? O SER D 404 
AB7 6 7 O SER D 403 ? O SER D 403 N ILE D 368 ? N ILE D 368 
AB7 7 8 O GLN D 369 ? O GLN D 369 N LEU D 323 ? N LEU D 323 
AB7 8 9 O LEU D 322 ? O LEU D 322 N ILE D 293 ? N ILE D 293 
# 
_pdbx_entry_details.entry_id                   8QRZ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 NH2 C ARG 252 ? ? O   C HOH 601 ? ? 2.00 
2  1 O   C ARG 219 ? ? NH1 D ARG 112 ? ? 2.06 
3  1 OE1 B GLN 369 ? ? RB  B RB  501 ? ? 2.10 
4  1 OE1 D GLN 369 ? ? RB  D RB  501 ? ? 2.11 
5  1 OE1 A GLN 369 ? ? RB  A RB  501 ? ? 2.11 
6  1 OE2 D GLU 292 ? ? RB  D RB  501 ? ? 2.11 
7  1 O   D SER 40  ? ? NH2 D ARG 112 ? ? 2.13 
8  1 OE2 B GLU 292 ? ? RB  B RB  501 ? ? 2.15 
9  1 OG  B SER 214 ? ? O   B HOH 601 ? ? 2.16 
10 1 O   A ARG 5   ? ? NH1 A ARG 30  ? ? 2.16 
11 1 OE2 C GLU 292 ? ? RB  C RB  501 ? ? 2.16 
12 1 OD2 A ASP 324 ? ? RB  A RB  501 ? ? 2.18 
13 1 OD2 B ASP 324 ? ? RB  B RB  501 ? ? 2.19 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             C 
_pdbx_validate_rmsd_angle.auth_asym_id_1             D 
_pdbx_validate_rmsd_angle.auth_comp_id_1             GLY 
_pdbx_validate_rmsd_angle.auth_seq_id_1              97 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             D 
_pdbx_validate_rmsd_angle.auth_comp_id_2             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_2              98 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_3             D 
_pdbx_validate_rmsd_angle.auth_comp_id_3             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_3              98 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                137.31 
_pdbx_validate_rmsd_angle.angle_target_value         121.70 
_pdbx_validate_rmsd_angle.angle_deviation            15.61 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.50 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 52  ? ? -130.34 -34.38 
2  1 ASP A 54  ? ? -160.12 102.21 
3  1 LEU A 94  ? ? -162.36 90.71  
4  1 SER A 153 ? ? 75.21   -46.80 
5  1 ASN A 189 ? ? -119.67 67.03  
6  1 THR A 210 ? ? -112.13 -91.22 
7  1 ASN A 226 ? ? -97.70  39.06  
8  1 GLN A 383 ? ? -141.03 -38.21 
9  1 GLU A 407 ? ? -145.28 38.89  
10 1 ARG A 410 ? ? -88.66  46.77  
11 1 TRP A 413 ? ? 72.49   -14.45 
12 1 LEU B 94  ? ? -161.15 99.03  
13 1 SER B 153 ? ? 83.26   -47.89 
14 1 ASN B 189 ? ? -118.77 68.93  
15 1 THR B 210 ? ? -110.05 -86.80 
16 1 ASN B 226 ? ? -97.47  36.09  
17 1 PRO B 341 ? ? -58.86  105.74 
18 1 ARG B 344 ? ? -58.37  170.55 
19 1 ASP B 374 ? ? -168.37 118.83 
20 1 GLN B 383 ? ? -132.73 -32.24 
21 1 PRO B 385 ? ? -69.03  88.55  
22 1 ARG B 410 ? ? -86.20  48.35  
23 1 TRP B 413 ? ? 73.74   -13.70 
24 1 LEU C 94  ? ? -167.54 90.83  
25 1 HIS C 120 ? ? -93.48  35.13  
26 1 SER C 153 ? ? 72.72   -41.79 
27 1 THR C 210 ? ? -114.12 -89.58 
28 1 ASN C 226 ? ? -97.46  40.12  
29 1 ARG C 228 ? ? -170.51 149.04 
30 1 LEU C 265 ? ? 73.89   35.12  
31 1 ASP C 374 ? ? -167.66 118.34 
32 1 GLN C 383 ? ? -137.14 -37.83 
33 1 ARG C 410 ? ? -92.08  43.01  
34 1 TRP C 413 ? ? 79.88   -10.25 
35 1 LEU D 52  ? ? -133.40 -41.98 
36 1 ASP D 54  ? ? -159.55 69.50  
37 1 SER D 153 ? ? 82.75   -46.13 
38 1 ASN D 189 ? ? -115.98 71.64  
39 1 THR D 210 ? ? -104.95 -83.90 
40 1 HIS D 221 ? ? -118.69 53.66  
41 1 ASN D 226 ? ? -99.81  41.40  
42 1 HIS D 301 ? ? -179.75 147.40 
43 1 HIS D 373 ? ? -134.75 -36.18 
44 1 GLN D 383 ? ? -142.21 -58.22 
45 1 GLU D 409 ? ? -38.76  124.10 
46 1 ARG D 410 ? ? -87.91  43.05  
47 1 TRP D 413 ? ? 70.41   -14.49 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
PHE N    N  N N 250 
PHE CA   C  N S 251 
PHE C    C  N N 252 
PHE O    O  N N 253 
PHE CB   C  N N 254 
PHE CG   C  Y N 255 
PHE CD1  C  Y N 256 
PHE CD2  C  Y N 257 
PHE CE1  C  Y N 258 
PHE CE2  C  Y N 259 
PHE CZ   C  Y N 260 
PHE OXT  O  N N 261 
PHE H    H  N N 262 
PHE H2   H  N N 263 
PHE HA   H  N N 264 
PHE HB2  H  N N 265 
PHE HB3  H  N N 266 
PHE HD1  H  N N 267 
PHE HD2  H  N N 268 
PHE HE1  H  N N 269 
PHE HE2  H  N N 270 
PHE HZ   H  N N 271 
PHE HXT  H  N N 272 
PRO N    N  N N 273 
PRO CA   C  N S 274 
PRO C    C  N N 275 
PRO O    O  N N 276 
PRO CB   C  N N 277 
PRO CG   C  N N 278 
PRO CD   C  N N 279 
PRO OXT  O  N N 280 
PRO H    H  N N 281 
PRO HA   H  N N 282 
PRO HB2  H  N N 283 
PRO HB3  H  N N 284 
PRO HG2  H  N N 285 
PRO HG3  H  N N 286 
PRO HD2  H  N N 287 
PRO HD3  H  N N 288 
PRO HXT  H  N N 289 
RB  RB   RB N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Other government' Sweden 'Formas 2017-00983'                                   1 
'Other private'    Sweden 'Oscar and Lili Lamm Memorial Foundation DO2017-0020' 2 
'Other government' Sweden 'VR 2017-03877'                                       3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   AF-A0A147EV52-F1 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8QRZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012784 
_atom_sites.fract_transf_matrix[1][2]   0.003808 
_atom_sites.fract_transf_matrix[1][3]   0.001082 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012976 
_atom_sites.fract_transf_matrix[2][3]   0.000338 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012094 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
O  
RB 
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . MET A 1 1   ? 0.860   17.625  0.196   1.00 44.41  ? 1   MET A N   1 
ATOM   2     C  CA  . MET A 1 1   ? 1.326   16.218  0.218   1.00 37.96  ? 1   MET A CA  1 
ATOM   3     C  C   . MET A 1 1   ? 2.840   16.215  0.429   1.00 39.28  ? 1   MET A C   1 
ATOM   4     O  O   . MET A 1 1   ? 3.517   17.014  -0.205  1.00 37.41  ? 1   MET A O   1 
ATOM   5     C  CB  . MET A 1 1   ? 0.995   15.516  -1.097  1.00 43.20  ? 1   MET A CB  1 
ATOM   6     C  CG  . MET A 1 1   ? -0.067  14.466  -0.989  1.00 38.14  ? 1   MET A CG  1 
ATOM   7     S  SD  . MET A 1 1   ? -0.340  13.745  -2.611  1.00 49.13  ? 1   MET A SD  1 
ATOM   8     C  CE  . MET A 1 1   ? -0.468  15.232  -3.601  1.00 34.16  ? 1   MET A CE  1 
ATOM   9     N  N   . LEU A 1 2   ? 3.335   15.332  1.280   1.00 28.65  ? 2   LEU A N   1 
ATOM   10    C  CA  . LEU A 1 2   ? 4.778   15.323  1.601   1.00 24.10  ? 2   LEU A CA  1 
ATOM   11    C  C   . LEU A 1 2   ? 5.606   14.680  0.486   1.00 25.50  ? 2   LEU A C   1 
ATOM   12    O  O   . LEU A 1 2   ? 5.080   13.822  -0.222  1.00 25.84  ? 2   LEU A O   1 
ATOM   13    C  CB  . LEU A 1 2   ? 4.963   14.604  2.937   1.00 28.41  ? 2   LEU A CB  1 
ATOM   14    C  CG  . LEU A 1 2   ? 4.441   15.362  4.155   1.00 27.98  ? 2   LEU A CG  1 
ATOM   15    C  CD1 . LEU A 1 2   ? 4.318   14.439  5.350   1.00 26.66  ? 2   LEU A CD1 1 
ATOM   16    C  CD2 . LEU A 1 2   ? 5.334   16.545  4.481   1.00 25.22  ? 2   LEU A CD2 1 
ATOM   17    N  N   . LEU A 1 3   ? 6.843   15.132  0.340   1.00 25.01  ? 3   LEU A N   1 
ATOM   18    C  CA  . LEU A 1 3   ? 7.762   14.616  -0.665  1.00 27.73  ? 3   LEU A CA  1 
ATOM   19    C  C   . LEU A 1 3   ? 8.750   13.654  -0.019  1.00 25.94  ? 3   LEU A C   1 
ATOM   20    O  O   . LEU A 1 3   ? 9.091   13.790  1.162   1.00 25.22  ? 3   LEU A O   1 
ATOM   21    C  CB  . LEU A 1 3   ? 8.528   15.766  -1.349  1.00 26.75  ? 3   LEU A CB  1 
ATOM   22    C  CG  . LEU A 1 3   ? 7.626   16.670  -2.193  1.00 25.09  ? 3   LEU A CG  1 
ATOM   23    C  CD1 . LEU A 1 3   ? 8.342   17.929  -2.698  1.00 27.10  ? 3   LEU A CD1 1 
ATOM   24    C  CD2 . LEU A 1 3   ? 7.011   15.887  -3.348  1.00 25.27  ? 3   LEU A CD2 1 
ATOM   25    N  N   . GLU A 1 4   ? 9.202   12.681  -0.812  1.00 25.08  ? 4   GLU A N   1 
ATOM   26    C  CA  . GLU A 1 4   ? 10.209  11.725  -0.373  1.00 26.75  ? 4   GLU A CA  1 
ATOM   27    C  C   . GLU A 1 4   ? 11.578  12.397  -0.249  1.00 30.07  ? 4   GLU A C   1 
ATOM   28    O  O   . GLU A 1 4   ? 11.886  13.383  -0.934  1.00 22.15  ? 4   GLU A O   1 
ATOM   29    C  CB  . GLU A 1 4   ? 10.254  10.527  -1.344  1.00 25.62  ? 4   GLU A CB  1 
ATOM   30    C  CG  . GLU A 1 4   ? 8.846   9.980   -1.660  1.00 25.55  ? 4   GLU A CG  1 
ATOM   31    C  CD  . GLU A 1 4   ? 8.767   9.014   -2.884  1.00 31.12  ? 4   GLU A CD  1 
ATOM   32    O  OE1 . GLU A 1 4   ? 9.808   8.459   -3.312  1.00 26.79  ? 4   GLU A OE1 1 
ATOM   33    O  OE2 . GLU A 1 4   ? 7.648   8.834   -3.424  1.00 32.69  ? 4   GLU A OE2 1 
ATOM   34    N  N   . ARG A 1 5   ? 12.401  11.853  0.654   1.00 29.91  ? 5   ARG A N   1 
ATOM   35    C  CA  . ARG A 1 5   ? 13.720  12.424  0.920   1.00 31.80  ? 5   ARG A CA  1 
ATOM   36    C  C   . ARG A 1 5   ? 14.619  12.373  -0.315  1.00 31.82  ? 5   ARG A C   1 
ATOM   37    O  O   . ARG A 1 5   ? 15.312  13.349  -0.639  1.00 34.79  ? 5   ARG A O   1 
ATOM   38    C  CB  . ARG A 1 5   ? 14.374  11.692  2.094   1.00 33.36  ? 5   ARG A CB  1 
ATOM   39    C  CG  . ARG A 1 5   ? 15.478  12.513  2.786   1.00 33.13  ? 5   ARG A CG  1 
ATOM   40    C  CD  . ARG A 1 5   ? 14.934  13.858  3.293   1.00 28.87  ? 5   ARG A CD  1 
ATOM   41    N  NE  . ARG A 1 5   ? 15.871  14.558  4.171   1.00 32.29  ? 5   ARG A NE  1 
ATOM   42    C  CZ  . ARG A 1 5   ? 15.557  15.121  5.332   1.00 26.43  ? 5   ARG A CZ  1 
ATOM   43    N  NH1 . ARG A 1 5   ? 14.319  15.097  5.804   1.00 30.62  ? 5   ARG A NH1 1 
ATOM   44    N  NH2 . ARG A 1 5   ? 16.504  15.744  6.028   1.00 27.90  ? 5   ARG A NH2 1 
ATOM   45    N  N   . ASP A 1 6   ? 14.594  11.250  -1.009  1.00 34.57  ? 6   ASP A N   1 
ATOM   46    C  CA  . ASP A 1 6   ? 15.376  11.123  -2.261  1.00 31.85  ? 6   ASP A CA  1 
ATOM   47    C  C   . ASP A 1 6   ? 14.842  12.134  -3.274  1.00 30.58  ? 6   ASP A C   1 
ATOM   48    O  O   . ASP A 1 6   ? 13.620  12.264  -3.383  1.00 28.46  ? 6   ASP A O   1 
ATOM   49    C  CB  . ASP A 1 6   ? 15.319  9.698   -2.804  1.00 36.17  ? 6   ASP A CB  1 
ATOM   50    C  CG  . ASP A 1 6   ? 16.000  8.668   -1.923  1.00 37.44  ? 6   ASP A CG  1 
ATOM   51    O  OD1 . ASP A 1 6   ? 16.964  9.036   -1.230  1.00 41.74  ? 6   ASP A OD1 1 
ATOM   52    O  OD2 . ASP A 1 6   ? 15.563  7.508   -1.944  1.00 37.65  ? 6   ASP A OD2 1 
ATOM   53    N  N   . LEU A 1 7   ? 15.752  12.820  -3.963  1.00 27.42  ? 7   LEU A N   1 
ATOM   54    C  CA  . LEU A 1 7   ? 15.330  13.824  -4.970  1.00 28.21  ? 7   LEU A CA  1 
ATOM   55    C  C   . LEU A 1 7   ? 14.469  13.103  -6.010  1.00 22.73  ? 7   LEU A C   1 
ATOM   56    O  O   . LEU A 1 7   ? 13.400  13.601  -6.322  1.00 25.13  ? 7   LEU A O   1 
ATOM   57    C  CB  . LEU A 1 7   ? 16.559  14.506  -5.569  1.00 23.13  ? 7   LEU A CB  1 
ATOM   58    C  CG  . LEU A 1 7   ? 17.455  15.267  -4.596  1.00 27.33  ? 7   LEU A CG  1 
ATOM   59    C  CD1 . LEU A 1 7   ? 18.649  15.847  -5.332  1.00 23.54  ? 7   LEU A CD1 1 
ATOM   60    C  CD2 . LEU A 1 7   ? 16.684  16.373  -3.899  1.00 37.22  ? 7   LEU A CD2 1 
ATOM   61    N  N   . ILE A 1 8   ? 14.915  11.935  -6.472  1.00 24.61  ? 8   ILE A N   1 
ATOM   62    C  CA  . ILE A 1 8   ? 14.075  11.134  -7.404  1.00 22.55  ? 8   ILE A CA  1 
ATOM   63    C  C   . ILE A 1 8   ? 12.941  10.507  -6.594  1.00 28.07  ? 8   ILE A C   1 
ATOM   64    O  O   . ILE A 1 8   ? 13.230  9.714   -5.709  1.00 31.55  ? 8   ILE A O   1 
ATOM   65    C  CB  . ILE A 1 8   ? 14.886  10.082  -8.183  1.00 24.59  ? 8   ILE A CB  1 
ATOM   66    C  CG1 . ILE A 1 8   ? 16.066  10.706  -8.930  1.00 28.98  ? 8   ILE A CG1 1 
ATOM   67    C  CG2 . ILE A 1 8   ? 13.978  9.296   -9.113  1.00 25.77  ? 8   ILE A CG2 1 
ATOM   68    C  CD1 . ILE A 1 8   ? 17.210  9.756   -9.175  1.00 30.51  ? 8   ILE A CD1 1 
ATOM   69    N  N   . GLN A 1 9   ? 11.706  10.906  -6.871  1.00 29.53  ? 9   GLN A N   1 
ATOM   70    C  CA  . GLN A 1 9   ? 10.554  10.302  -6.202  1.00 26.30  ? 9   GLN A CA  1 
ATOM   71    C  C   . GLN A 1 9   ? 10.275  8.927   -6.784  1.00 27.35  ? 9   GLN A C   1 
ATOM   72    O  O   . GLN A 1 9   ? 10.433  8.709   -7.988  1.00 24.05  ? 9   GLN A O   1 
ATOM   73    C  CB  . GLN A 1 9   ? 9.303   11.168  -6.361  1.00 23.52  ? 9   GLN A CB  1 
ATOM   74    C  CG  . GLN A 1 9   ? 9.456   12.598  -5.938  1.00 22.80  ? 9   GLN A CG  1 
ATOM   75    C  CD  . GLN A 1 9   ? 9.708   12.753  -4.429  1.00 30.09  ? 9   GLN A CD  1 
ATOM   76    O  OE1 . GLN A 1 9   ? 8.803   12.574  -3.598  1.00 25.83  ? 9   GLN A OE1 1 
ATOM   77    N  NE2 . GLN A 1 9   ? 10.960  13.054  -4.075  1.00 24.14  ? 9   GLN A NE2 1 
ATOM   78    N  N   . SER A 1 10  ? 9.864   7.986   -5.924  1.00 24.27  ? 10  SER A N   1 
ATOM   79    C  CA  . SER A 1 10  ? 9.288   6.751   -6.442  1.00 28.25  ? 10  SER A CA  1 
ATOM   80    C  C   . SER A 1 10  ? 7.908   6.999   -7.026  1.00 25.74  ? 10  SER A C   1 
ATOM   81    O  O   . SER A 1 10  ? 7.582   6.486   -8.102  1.00 26.37  ? 10  SER A O   1 
ATOM   82    C  CB  . SER A 1 10  ? 9.208   5.685   -5.348  1.00 28.96  ? 10  SER A CB  1 
ATOM   83    O  OG  . SER A 1 10  ? 10.449  5.013   -5.227  1.00 30.83  ? 10  SER A OG  1 
ATOM   84    N  N   . VAL A 1 11  ? 7.084   7.796   -6.347  1.00 24.83  ? 11  VAL A N   1 
ATOM   85    C  CA  . VAL A 1 11  ? 5.716   7.994   -6.817  1.00 24.53  ? 11  VAL A CA  1 
ATOM   86    C  C   . VAL A 1 11  ? 5.709   8.848   -8.086  1.00 30.79  ? 11  VAL A C   1 
ATOM   87    O  O   . VAL A 1 11  ? 6.370   9.894   -8.159  1.00 28.04  ? 11  VAL A O   1 
ATOM   88    C  CB  . VAL A 1 11  ? 4.865   8.604   -5.699  1.00 25.48  ? 11  VAL A CB  1 
ATOM   89    C  CG1 . VAL A 1 11  ? 3.458   8.821   -6.173  1.00 23.12  ? 11  VAL A CG1 1 
ATOM   90    C  CG2 . VAL A 1 11  ? 4.883   7.654   -4.479  1.00 20.30  ? 11  VAL A CG2 1 
ATOM   91    N  N   . GLY A 1 12  ? 4.973   8.391   -9.109  1.00 26.94  ? 12  GLY A N   1 
ATOM   92    C  CA  . GLY A 1 12  ? 4.877   9.091   -10.371 1.00 26.16  ? 12  GLY A CA  1 
ATOM   93    C  C   . GLY A 1 12  ? 5.773   8.570   -11.484 1.00 31.66  ? 12  GLY A C   1 
ATOM   94    O  O   . GLY A 1 12  ? 5.657   9.048   -12.628 1.00 27.52  ? 12  GLY A O   1 
ATOM   95    N  N   . PHE A 1 13  ? 6.663   7.619   -11.187 1.00 28.35  ? 13  PHE A N   1 
ATOM   96    C  CA  . PHE A 1 13  ? 7.559   7.013   -12.173 1.00 24.06  ? 13  PHE A CA  1 
ATOM   97    C  C   . PHE A 1 13  ? 6.752   6.013   -12.992 1.00 32.48  ? 13  PHE A C   1 
ATOM   98    O  O   . PHE A 1 13  ? 6.490   4.884   -12.551 1.00 25.74  ? 13  PHE A O   1 
ATOM   99    C  CB  . PHE A 1 13  ? 8.730   6.340   -11.471 1.00 26.25  ? 13  PHE A CB  1 
ATOM   100   C  CG  . PHE A 1 13  ? 9.647   5.589   -12.390 1.00 28.75  ? 13  PHE A CG  1 
ATOM   101   C  CD1 . PHE A 1 13  ? 10.152  6.196   -13.540 1.00 28.61  ? 13  PHE A CD1 1 
ATOM   102   C  CD2 . PHE A 1 13  ? 10.028  4.280   -12.095 1.00 22.78  ? 13  PHE A CD2 1 
ATOM   103   C  CE1 . PHE A 1 13  ? 11.017  5.516   -14.372 1.00 27.31  ? 13  PHE A CE1 1 
ATOM   104   C  CE2 . PHE A 1 13  ? 10.883  3.587   -12.922 1.00 25.27  ? 13  PHE A CE2 1 
ATOM   105   C  CZ  . PHE A 1 13  ? 11.384  4.195   -14.059 1.00 29.78  ? 13  PHE A CZ  1 
ATOM   106   N  N   . ARG A 1 14  ? 6.347   6.426   -14.190 1.00 26.54  ? 14  ARG A N   1 
ATOM   107   C  CA  . ARG A 1 14  ? 5.342   5.689   -14.940 1.00 28.33  ? 14  ARG A CA  1 
ATOM   108   C  C   . ARG A 1 14  ? 5.509   6.028   -16.412 1.00 28.44  ? 14  ARG A C   1 
ATOM   109   O  O   . ARG A 1 14  ? 6.091   7.059   -16.766 1.00 24.67  ? 14  ARG A O   1 
ATOM   110   C  CB  . ARG A 1 14  ? 3.925   6.028   -14.451 1.00 30.42  ? 14  ARG A CB  1 
ATOM   111   C  CG  . ARG A 1 14  ? 3.548   7.524   -14.611 1.00 30.50  ? 14  ARG A CG  1 
ATOM   112   C  CD  . ARG A 1 14  ? 2.074   7.712   -14.847 1.00 29.55  ? 14  ARG A CD  1 
ATOM   113   N  NE  . ARG A 1 14  ? 1.290   7.214   -13.729 1.00 43.34  ? 14  ARG A NE  1 
ATOM   114   C  CZ  . ARG A 1 14  ? 0.421   6.215   -13.803 1.00 41.75  ? 14  ARG A CZ  1 
ATOM   115   N  NH1 . ARG A 1 14  ? 0.184   5.585   -14.941 1.00 46.42  ? 14  ARG A NH1 1 
ATOM   116   N  NH2 . ARG A 1 14  ? -0.210  5.824   -12.701 1.00 41.13  ? 14  ARG A NH2 1 
ATOM   117   N  N   . ASN A 1 15  ? 5.043   5.120   -17.265 1.00 22.42  ? 15  ASN A N   1 
ATOM   118   C  CA  . ASN A 1 15  ? 4.983   5.417   -18.683 1.00 26.94  ? 15  ASN A CA  1 
ATOM   119   C  C   . ASN A 1 15  ? 3.825   6.367   -18.950 1.00 28.63  ? 15  ASN A C   1 
ATOM   120   O  O   . ASN A 1 15  ? 2.809   6.358   -18.250 1.00 28.08  ? 15  ASN A O   1 
ATOM   121   C  CB  . ASN A 1 15  ? 4.780   4.145   -19.512 1.00 30.18  ? 15  ASN A CB  1 
ATOM   122   C  CG  . ASN A 1 15  ? 6.034   3.318   -19.647 1.00 27.77  ? 15  ASN A CG  1 
ATOM   123   O  OD1 . ASN A 1 15  ? 7.151   3.837   -19.764 1.00 28.32  ? 15  ASN A OD1 1 
ATOM   124   N  ND2 . ASN A 1 15  ? 5.855   2.008   -19.624 1.00 33.78  ? 15  ASN A ND2 1 
ATOM   125   N  N   . VAL A 1 16  ? 3.953   7.157   -20.010 1.00 28.64  ? 16  VAL A N   1 
ATOM   126   C  CA  . VAL A 1 16  ? 2.955   8.161   -20.343 1.00 33.32  ? 16  VAL A CA  1 
ATOM   127   C  C   . VAL A 1 16  ? 2.337   7.806   -21.683 1.00 32.39  ? 16  VAL A C   1 
ATOM   128   O  O   . VAL A 1 16  ? 3.051   7.472   -22.632 1.00 31.40  ? 16  VAL A O   1 
ATOM   129   C  CB  . VAL A 1 16  ? 3.569   9.568   -20.347 1.00 34.56  ? 16  VAL A CB  1 
ATOM   130   C  CG1 . VAL A 1 16  ? 2.733   10.537  -21.188 1.00 33.30  ? 16  VAL A CG1 1 
ATOM   131   C  CG2 . VAL A 1 16  ? 3.707   10.035  -18.896 1.00 30.53  ? 16  VAL A CG2 1 
ATOM   132   N  N   A ARG A 1 17  ? 1.012   7.867   -21.753 0.57 34.12  ? 17  ARG A N   1 
ATOM   133   N  N   B ARG A 1 17  ? 1.013   7.869   -21.750 0.43 33.79  ? 17  ARG A N   1 
ATOM   134   C  CA  A ARG A 1 17  ? 0.265   7.465   -22.932 0.57 38.92  ? 17  ARG A CA  1 
ATOM   135   C  CA  B ARG A 1 17  ? 0.267   7.481   -22.933 0.43 38.91  ? 17  ARG A CA  1 
ATOM   136   C  C   A ARG A 1 17  ? -0.544  8.639   -23.468 0.57 40.21  ? 17  ARG A C   1 
ATOM   137   C  C   B ARG A 1 17  ? -0.509  8.671   -23.476 0.43 40.19  ? 17  ARG A C   1 
ATOM   138   O  O   A ARG A 1 17  ? -0.964  9.525   -22.716 0.57 40.80  ? 17  ARG A O   1 
ATOM   139   O  O   B ARG A 1 17  ? -0.870  9.594   -22.741 0.43 40.78  ? 17  ARG A O   1 
ATOM   140   C  CB  A ARG A 1 17  ? -0.683  6.286   -22.625 0.57 39.43  ? 17  ARG A CB  1 
ATOM   141   C  CB  B ARG A 1 17  ? -0.705  6.333   -22.628 0.43 39.43  ? 17  ARG A CB  1 
ATOM   142   C  CG  A ARG A 1 17  ? -0.004  5.045   -22.051 0.57 38.52  ? 17  ARG A CG  1 
ATOM   143   C  CG  B ARG A 1 17  ? -0.063  4.963   -22.647 0.43 39.23  ? 17  ARG A CG  1 
ATOM   144   C  CD  A ARG A 1 17  ? -1.038  4.023   -21.591 0.57 42.07  ? 17  ARG A CD  1 
ATOM   145   C  CD  B ARG A 1 17  ? -1.076  3.879   -22.332 0.43 42.24  ? 17  ARG A CD  1 
ATOM   146   N  NE  A ARG A 1 17  ? -0.470  2.683   -21.474 0.57 44.85  ? 17  ARG A NE  1 
ATOM   147   N  NE  B ARG A 1 17  ? -0.452  2.570   -22.180 0.43 43.99  ? 17  ARG A NE  1 
ATOM   148   C  CZ  A ARG A 1 17  ? -0.317  1.845   -22.491 0.57 41.42  ? 17  ARG A CZ  1 
ATOM   149   C  CZ  B ARG A 1 17  ? 0.348   2.227   -21.178 0.43 42.70  ? 17  ARG A CZ  1 
ATOM   150   N  NH1 A ARG A 1 17  ? -0.698  2.167   -23.715 0.57 44.43  ? 17  ARG A NH1 1 
ATOM   151   N  NH1 B ARG A 1 17  ? 0.658   3.081   -20.212 0.43 36.84  ? 17  ARG A NH1 1 
ATOM   152   N  NH2 A ARG A 1 17  ? 0.235   0.656   -22.275 0.57 41.61  ? 17  ARG A NH2 1 
ATOM   153   N  NH2 B ARG A 1 17  ? 0.853   0.998   -21.146 0.43 42.39  ? 17  ARG A NH2 1 
ATOM   154   N  N   . GLU A 1 18  ? -0.758  8.634   -24.780 1.00 33.49  ? 18  GLU A N   1 
ATOM   155   C  CA  . GLU A 1 18  ? -1.627  9.592   -25.445 1.00 41.61  ? 18  GLU A CA  1 
ATOM   156   C  C   . GLU A 1 18  ? -2.378  8.799   -26.488 1.00 38.17  ? 18  GLU A C   1 
ATOM   157   O  O   . GLU A 1 18  ? -1.750  8.103   -27.296 1.00 41.67  ? 18  GLU A O   1 
ATOM   158   C  CB  . GLU A 1 18  ? -0.839  10.730  -26.101 1.00 46.98  ? 18  GLU A CB  1 
ATOM   159   C  CG  . GLU A 1 18  ? -0.641  11.923  -25.223 1.00 47.31  ? 18  GLU A CG  1 
ATOM   160   C  CD  . GLU A 1 18  ? 0.607   12.684  -25.598 1.00 55.47  ? 18  GLU A CD  1 
ATOM   161   O  OE1 . GLU A 1 18  ? 0.581   13.398  -26.631 1.00 53.82  ? 18  GLU A OE1 1 
ATOM   162   O  OE2 . GLU A 1 18  ? 1.617   12.554  -24.868 1.00 54.97  ? 18  GLU A OE2 1 
ATOM   163   N  N   . GLY A 1 19  ? -3.702  8.867   -26.439 1.00 43.26  ? 19  GLY A N   1 
ATOM   164   C  CA  . GLY A 1 19  ? -4.545  8.075   -27.319 1.00 44.36  ? 19  GLY A CA  1 
ATOM   165   C  C   . GLY A 1 19  ? -4.168  6.607   -27.400 1.00 46.33  ? 19  GLY A C   1 
ATOM   166   O  O   . GLY A 1 19  ? -4.252  6.001   -28.472 1.00 51.82  ? 19  GLY A O   1 
ATOM   167   N  N   . GLY A 1 20  ? -3.733  6.022   -26.283 1.00 47.03  ? 20  GLY A N   1 
ATOM   168   C  CA  . GLY A 1 20  ? -3.431  4.606   -26.206 1.00 46.51  ? 20  GLY A CA  1 
ATOM   169   C  C   . GLY A 1 20  ? -1.976  4.242   -26.435 1.00 44.55  ? 20  GLY A C   1 
ATOM   170   O  O   . GLY A 1 20  ? -1.499  3.258   -25.864 1.00 53.33  ? 20  GLY A O   1 
ATOM   171   N  N   . GLU A 1 21  ? -1.267  5.002   -27.260 1.00 45.43  ? 21  GLU A N   1 
ATOM   172   C  CA  . GLU A 1 21  ? 0.133   4.738   -27.548 1.00 48.38  ? 21  GLU A CA  1 
ATOM   173   C  C   . GLU A 1 21  ? 1.042   5.345   -26.480 1.00 46.37  ? 21  GLU A C   1 
ATOM   174   O  O   . GLU A 1 21  ? 0.784   6.442   -25.976 1.00 44.29  ? 21  GLU A O   1 
ATOM   175   C  CB  . GLU A 1 21  ? 0.487   5.295   -28.925 1.00 56.32  ? 21  GLU A CB  1 
ATOM   176   C  CG  . GLU A 1 21  ? 0.526   4.233   -30.009 1.00 58.53  ? 21  GLU A CG  1 
ATOM   177   C  CD  . GLU A 1 21  ? 1.424   3.060   -29.639 1.00 65.08  ? 21  GLU A CD  1 
ATOM   178   O  OE1 . GLU A 1 21  ? 2.467   3.283   -28.977 1.00 54.12  ? 21  GLU A OE1 1 
ATOM   179   O  OE2 . GLU A 1 21  ? 1.075   1.909   -29.992 1.00 70.69  ? 21  GLU A OE2 1 
ATOM   180   N  N   . ILE A 1 22  ? 2.109   4.627   -26.134 1.00 45.62  ? 22  ILE A N   1 
ATOM   181   C  CA  . ILE A 1 22  ? 3.054   5.122   -25.138 1.00 41.80  ? 22  ILE A CA  1 
ATOM   182   C  C   . ILE A 1 22  ? 4.073   6.014   -25.824 1.00 37.57  ? 22  ILE A C   1 
ATOM   183   O  O   . ILE A 1 22  ? 4.813   5.561   -26.703 1.00 37.49  ? 22  ILE A O   1 
ATOM   184   C  CB  . ILE A 1 22  ? 3.765   3.985   -24.394 1.00 39.36  ? 22  ILE A CB  1 
ATOM   185   C  CG1 . ILE A 1 22  ? 2.775   3.070   -23.675 1.00 39.82  ? 22  ILE A CG1 1 
ATOM   186   C  CG2 . ILE A 1 22  ? 4.727   4.592   -23.375 1.00 27.04  ? 22  ILE A CG2 1 
ATOM   187   C  CD1 . ILE A 1 22  ? 3.445   1.991   -22.900 1.00 37.67  ? 22  ILE A CD1 1 
ATOM   188   N  N   . THR A 1 23  ? 4.158   7.261   -25.363 1.00 36.76  ? 23  THR A N   1 
ATOM   189   C  CA  . THR A 1 23  ? 5.023   8.308   -25.899 1.00 34.01  ? 23  THR A CA  1 
ATOM   190   C  C   . THR A 1 23  ? 6.315   8.486   -25.116 1.00 34.21  ? 23  THR A C   1 
ATOM   191   O  O   . THR A 1 23  ? 7.269   9.077   -25.631 1.00 28.68  ? 23  THR A O   1 
ATOM   192   C  CB  . THR A 1 23  ? 4.260   9.629   -25.873 1.00 40.89  ? 23  THR A CB  1 
ATOM   193   O  OG1 . THR A 1 23  ? 3.995   9.958   -24.504 1.00 37.73  ? 23  THR A OG1 1 
ATOM   194   C  CG2 . THR A 1 23  ? 2.920   9.471   -26.587 1.00 42.55  ? 23  THR A CG2 1 
ATOM   195   N  N   . GLY A 1 24  ? 6.355   8.021   -23.874 1.00 32.40  ? 24  GLY A N   1 
ATOM   196   C  CA  . GLY A 1 24  ? 7.579   8.083   -23.102 1.00 31.91  ? 24  GLY A CA  1 
ATOM   197   C  C   . GLY A 1 24  ? 7.287   7.714   -21.665 1.00 31.83  ? 24  GLY A C   1 
ATOM   198   O  O   . GLY A 1 24  ? 6.285   7.048   -21.372 1.00 31.99  ? 24  GLY A O   1 
ATOM   199   N  N   . PHE A 1 25  ? 8.157   8.176   -20.774 1.00 30.77  ? 25  PHE A N   1 
ATOM   200   C  CA  . PHE A 1 25  ? 7.953   7.960   -19.352 1.00 28.22  ? 25  PHE A CA  1 
ATOM   201   C  C   . PHE A 1 25  ? 8.196   9.264   -18.613 1.00 29.53  ? 25  PHE A C   1 
ATOM   202   O  O   . PHE A 1 25  ? 8.821   10.191  -19.137 1.00 26.72  ? 25  PHE A O   1 
ATOM   203   C  CB  . PHE A 1 25  ? 8.858   6.843   -18.815 1.00 26.31  ? 25  PHE A CB  1 
ATOM   204   C  CG  . PHE A 1 25  ? 10.316  7.201   -18.759 1.00 30.84  ? 25  PHE A CG  1 
ATOM   205   C  CD1 . PHE A 1 25  ? 10.861  7.795   -17.635 1.00 23.41  ? 25  PHE A CD1 1 
ATOM   206   C  CD2 . PHE A 1 25  ? 11.142  6.932   -19.824 1.00 31.57  ? 25  PHE A CD2 1 
ATOM   207   C  CE1 . PHE A 1 25  ? 12.189  8.116   -17.582 1.00 29.27  ? 25  PHE A CE1 1 
ATOM   208   C  CE2 . PHE A 1 25  ? 12.472  7.248   -19.771 1.00 32.12  ? 25  PHE A CE2 1 
ATOM   209   C  CZ  . PHE A 1 25  ? 13.000  7.846   -18.645 1.00 35.00  ? 25  PHE A CZ  1 
ATOM   210   N  N   . GLN A 1 26  ? 7.674   9.331   -17.392 1.00 24.03  ? 26  GLN A N   1 
ATOM   211   C  CA  . GLN A 1 26  ? 7.931   10.447  -16.498 1.00 25.71  ? 26  GLN A CA  1 
ATOM   212   C  C   . GLN A 1 26  ? 8.447   9.937   -15.160 1.00 28.62  ? 26  GLN A C   1 
ATOM   213   O  O   . GLN A 1 26  ? 8.320   8.759   -14.817 1.00 30.30  ? 26  GLN A O   1 
ATOM   214   C  CB  . GLN A 1 26  ? 6.680   11.322  -16.269 1.00 25.95  ? 26  GLN A CB  1 
ATOM   215   C  CG  . GLN A 1 26  ? 5.475   10.579  -15.710 1.00 27.76  ? 26  GLN A CG  1 
ATOM   216   C  CD  . GLN A 1 26  ? 4.436   11.508  -15.153 1.00 29.45  ? 26  GLN A CD  1 
ATOM   217   O  OE1 . GLN A 1 26  ? 3.750   12.214  -15.889 1.00 28.21  ? 26  GLN A OE1 1 
ATOM   218   N  NE2 . GLN A 1 26  ? 4.319   11.531  -13.830 1.00 35.44  ? 26  GLN A NE2 1 
ATOM   219   N  N   . PHE A 1 27  ? 9.051   10.850  -14.409 1.00 26.90  ? 27  PHE A N   1 
ATOM   220   C  CA  . PHE A 1 27  ? 9.320   10.643  -12.993 1.00 28.24  ? 27  PHE A CA  1 
ATOM   221   C  C   . PHE A 1 27  ? 9.202   12.004  -12.331 1.00 29.85  ? 27  PHE A C   1 
ATOM   222   O  O   . PHE A 1 27  ? 9.073   13.023  -13.009 1.00 25.82  ? 27  PHE A O   1 
ATOM   223   C  CB  . PHE A 1 27  ? 10.694  10.020  -12.761 1.00 27.31  ? 27  PHE A CB  1 
ATOM   224   C  CG  . PHE A 1 27  ? 11.813  10.843  -13.289 1.00 27.51  ? 27  PHE A CG  1 
ATOM   225   C  CD1 . PHE A 1 27  ? 12.120  10.818  -14.646 1.00 32.47  ? 27  PHE A CD1 1 
ATOM   226   C  CD2 . PHE A 1 27  ? 12.543  11.672  -12.454 1.00 27.67  ? 27  PHE A CD2 1 
ATOM   227   C  CE1 . PHE A 1 27  ? 13.149  11.606  -15.152 1.00 29.31  ? 27  PHE A CE1 1 
ATOM   228   C  CE2 . PHE A 1 27  ? 13.569  12.443  -12.962 1.00 29.60  ? 27  PHE A CE2 1 
ATOM   229   C  CZ  . PHE A 1 27  ? 13.873  12.405  -14.302 1.00 31.03  ? 27  PHE A CZ  1 
ATOM   230   N  N   . ARG A 1 28  ? 9.242   12.026  -11.001 1.00 23.88  ? 28  ARG A N   1 
ATOM   231   C  CA  . ARG A 1 28  ? 9.077   13.271  -10.261 1.00 22.53  ? 28  ARG A CA  1 
ATOM   232   C  C   . ARG A 1 28  ? 10.349  13.580  -9.475  1.00 27.77  ? 28  ARG A C   1 
ATOM   233   O  O   . ARG A 1 28  ? 11.089  12.672  -9.100  1.00 29.63  ? 28  ARG A O   1 
ATOM   234   C  CB  . ARG A 1 28  ? 7.863   13.190  -9.348  1.00 26.00  ? 28  ARG A CB  1 
ATOM   235   C  CG  . ARG A 1 28  ? 6.565   13.551  -10.087 1.00 27.22  ? 28  ARG A CG  1 
ATOM   236   C  CD  . ARG A 1 28  ? 5.357   12.976  -9.397  1.00 24.26  ? 28  ARG A CD  1 
ATOM   237   N  NE  . ARG A 1 28  ? 5.069   13.762  -8.206  1.00 25.54  ? 28  ARG A NE  1 
ATOM   238   C  CZ  . ARG A 1 28  ? 5.356   13.374  -6.972  1.00 22.73  ? 28  ARG A CZ  1 
ATOM   239   N  NH1 . ARG A 1 28  ? 5.875   12.180  -6.729  1.00 20.20  ? 28  ARG A NH1 1 
ATOM   240   N  NH2 . ARG A 1 28  ? 5.125   14.209  -5.955  1.00 24.29  ? 28  ARG A NH2 1 
ATOM   241   N  N   . VAL A 1 29  ? 10.625  14.870  -9.246  1.00 24.71  ? 29  VAL A N   1 
ATOM   242   C  CA  . VAL A 1 29  ? 11.903  15.290  -8.661  1.00 24.04  ? 29  VAL A CA  1 
ATOM   243   C  C   . VAL A 1 29  ? 11.611  16.363  -7.639  1.00 21.73  ? 29  VAL A C   1 
ATOM   244   O  O   . VAL A 1 29  ? 11.061  17.410  -7.988  1.00 26.03  ? 29  VAL A O   1 
ATOM   245   C  CB  . VAL A 1 29  ? 12.899  15.833  -9.706  1.00 27.26  ? 29  VAL A CB  1 
ATOM   246   C  CG1 . VAL A 1 29  ? 14.181  16.412  -9.026  1.00 21.98  ? 29  VAL A CG1 1 
ATOM   247   C  CG2 . VAL A 1 29  ? 13.283  14.755  -10.661 1.00 23.15  ? 29  VAL A CG2 1 
ATOM   248   N  N   . ARG A 1 30  ? 11.997  16.130  -6.392  1.00 22.91  ? 30  ARG A N   1 
ATOM   249   C  CA  . ARG A 1 30  ? 11.820  17.170  -5.391  1.00 20.70  ? 30  ARG A CA  1 
ATOM   250   C  C   . ARG A 1 30  ? 12.943  18.202  -5.549  1.00 22.01  ? 30  ARG A C   1 
ATOM   251   O  O   . ARG A 1 30  ? 14.098  17.851  -5.781  1.00 19.88  ? 30  ARG A O   1 
ATOM   252   C  CB  . ARG A 1 30  ? 11.759  16.554  -3.981  1.00 26.03  ? 30  ARG A CB  1 
ATOM   253   C  CG  . ARG A 1 30  ? 12.905  16.846  -3.040  1.00 30.77  ? 30  ARG A CG  1 
ATOM   254   C  CD  . ARG A 1 30  ? 12.663  16.364  -1.560  1.00 24.40  ? 30  ARG A CD  1 
ATOM   255   N  NE  . ARG A 1 30  ? 13.676  16.983  -0.724  1.00 37.55  ? 30  ARG A NE  1 
ATOM   256   C  CZ  . ARG A 1 30  ? 14.942  16.596  -0.640  1.00 32.89  ? 30  ARG A CZ  1 
ATOM   257   N  NH1 . ARG A 1 30  ? 15.357  15.450  -1.148  1.00 37.38  ? 30  ARG A NH1 1 
ATOM   258   N  NH2 . ARG A 1 30  ? 15.811  17.368  -0.001  1.00 42.24  ? 30  ARG A NH2 1 
ATOM   259   N  N   . MET A 1 31  ? 12.583  19.466  -5.505  1.00 28.38  ? 31  MET A N   1 
ATOM   260   C  CA  . MET A 1 31  ? 13.555  20.543  -5.612  1.00 25.55  ? 31  MET A CA  1 
ATOM   261   C  C   . MET A 1 31  ? 14.650  20.358  -4.564  1.00 28.38  ? 31  MET A C   1 
ATOM   262   O  O   . MET A 1 31  ? 14.337  20.164  -3.382  1.00 26.99  ? 31  MET A O   1 
ATOM   263   C  CB  . MET A 1 31  ? 12.832  21.874  -5.406  1.00 23.97  ? 31  MET A CB  1 
ATOM   264   C  CG  . MET A 1 31  ? 13.707  23.055  -5.100  1.00 30.93  ? 31  MET A CG  1 
ATOM   265   S  SD  . MET A 1 31  ? 14.841  23.399  -6.429  1.00 30.04  ? 31  MET A SD  1 
ATOM   266   C  CE  . MET A 1 31  ? 14.011  24.799  -7.200  1.00 25.22  ? 31  MET A CE  1 
ATOM   267   N  N   . PRO A 1 32  ? 15.934  20.382  -4.948  1.00 26.32  ? 32  PRO A N   1 
ATOM   268   C  CA  . PRO A 1 32  ? 17.005  20.192  -3.943  1.00 28.05  ? 32  PRO A CA  1 
ATOM   269   C  C   . PRO A 1 32  ? 17.361  21.464  -3.171  1.00 27.53  ? 32  PRO A C   1 
ATOM   270   O  O   . PRO A 1 32  ? 17.788  21.403  -2.011  1.00 26.26  ? 32  PRO A O   1 
ATOM   271   C  CB  . PRO A 1 32  ? 18.186  19.694  -4.785  1.00 25.64  ? 32  PRO A CB  1 
ATOM   272   C  CG  . PRO A 1 32  ? 17.940  20.279  -6.153  1.00 27.84  ? 32  PRO A CG  1 
ATOM   273   C  CD  . PRO A 1 32  ? 16.431  20.291  -6.327  1.00 26.33  ? 32  PRO A CD  1 
ATOM   274   N  N   . SER A 1 33  ? 17.169  22.623  -3.799  1.00 30.69  ? 33  SER A N   1 
ATOM   275   C  CA  . SER A 1 33  ? 17.535  23.902  -3.202  1.00 28.56  ? 33  SER A CA  1 
ATOM   276   C  C   . SER A 1 33  ? 16.637  24.218  -1.998  1.00 30.52  ? 33  SER A C   1 
ATOM   277   O  O   . SER A 1 33  ? 15.602  23.590  -1.760  1.00 29.40  ? 33  SER A O   1 
ATOM   278   C  CB  . SER A 1 33  ? 17.470  25.007  -4.267  1.00 25.37  ? 33  SER A CB  1 
ATOM   279   O  OG  . SER A 1 33  ? 17.589  26.300  -3.717  1.00 28.66  ? 33  SER A OG  1 
ATOM   280   N  N   . TYR A 1 34  ? 17.060  25.188  -1.199  1.00 29.86  ? 34  TYR A N   1 
ATOM   281   C  CA  . TYR A 1 34  ? 16.237  25.535  -0.057  1.00 28.52  ? 34  TYR A CA  1 
ATOM   282   C  C   . TYR A 1 34  ? 15.009  26.356  -0.422  1.00 32.25  ? 34  TYR A C   1 
ATOM   283   O  O   . TYR A 1 34  ? 14.201  26.633  0.472   1.00 35.84  ? 34  TYR A O   1 
ATOM   284   C  CB  . TYR A 1 34  ? 17.047  26.286  1.005   1.00 33.95  ? 34  TYR A CB  1 
ATOM   285   C  CG  . TYR A 1 34  ? 18.077  27.249  0.486   1.00 36.90  ? 34  TYR A CG  1 
ATOM   286   C  CD1 . TYR A 1 34  ? 17.704  28.486  -0.038  1.00 39.88  ? 34  TYR A CD1 1 
ATOM   287   C  CD2 . TYR A 1 34  ? 19.433  26.954  0.568   1.00 38.55  ? 34  TYR A CD2 1 
ATOM   288   C  CE1 . TYR A 1 34  ? 18.661  29.394  -0.504  1.00 34.13  ? 34  TYR A CE1 1 
ATOM   289   C  CE2 . TYR A 1 34  ? 20.393  27.857  0.111   1.00 43.86  ? 34  TYR A CE2 1 
ATOM   290   C  CZ  . TYR A 1 34  ? 20.001  29.073  -0.414  1.00 40.35  ? 34  TYR A CZ  1 
ATOM   291   O  OH  . TYR A 1 34  ? 20.958  29.956  -0.870  1.00 46.85  ? 34  TYR A OH  1 
ATOM   292   N  N   . ARG A 1 35  ? 14.823  26.730  -1.693  1.00 26.12  ? 35  ARG A N   1 
ATOM   293   C  CA  . ARG A 1 35  ? 13.640  27.477  -2.083  1.00 23.48  ? 35  ARG A CA  1 
ATOM   294   C  C   . ARG A 1 35  ? 13.119  26.965  -3.409  1.00 21.70  ? 35  ARG A C   1 
ATOM   295   O  O   . ARG A 1 35  ? 13.870  26.426  -4.218  1.00 23.22  ? 35  ARG A O   1 
ATOM   296   C  CB  . ARG A 1 35  ? 13.919  28.993  -2.195  1.00 27.73  ? 35  ARG A CB  1 
ATOM   297   C  CG  . ARG A 1 35  ? 15.045  29.352  -3.117  1.00 29.02  ? 35  ARG A CG  1 
ATOM   298   C  CD  . ARG A 1 35  ? 14.975  30.806  -3.587  1.00 24.19  ? 35  ARG A CD  1 
ATOM   299   N  NE  . ARG A 1 35  ? 16.088  31.040  -4.486  1.00 31.44  ? 35  ARG A NE  1 
ATOM   300   C  CZ  . ARG A 1 35  ? 16.165  32.002  -5.392  1.00 26.53  ? 35  ARG A CZ  1 
ATOM   301   N  NH1 . ARG A 1 35  ? 15.218  32.917  -5.518  1.00 24.60  ? 35  ARG A NH1 1 
ATOM   302   N  NH2 . ARG A 1 35  ? 17.213  32.032  -6.205  1.00 27.44  ? 35  ARG A NH2 1 
ATOM   303   N  N   . GLY A 1 36  ? 11.818  27.120  -3.620  1.00 24.42  ? 36  GLY A N   1 
ATOM   304   C  CA  . GLY A 1 36  ? 11.320  27.140  -4.973  1.00 21.07  ? 36  GLY A CA  1 
ATOM   305   C  C   . GLY A 1 36  ? 11.879  28.339  -5.706  1.00 24.23  ? 36  GLY A C   1 
ATOM   306   O  O   . GLY A 1 36  ? 12.399  29.269  -5.089  1.00 24.73  ? 36  GLY A O   1 
ATOM   307   N  N   . MET A 1 37  ? 11.810  28.317  -7.037  1.00 26.53  ? 37  MET A N   1 
ATOM   308   C  CA  . MET A 1 37  ? 12.405  29.426  -7.771  1.00 21.48  ? 37  MET A CA  1 
ATOM   309   C  C   . MET A 1 37  ? 11.746  29.586  -9.123  1.00 23.04  ? 37  MET A C   1 
ATOM   310   O  O   . MET A 1 37  ? 10.925  28.769  -9.540  1.00 28.94  ? 37  MET A O   1 
ATOM   311   C  CB  . MET A 1 37  ? 13.917  29.271  -7.929  1.00 26.10  ? 37  MET A CB  1 
ATOM   312   C  CG  . MET A 1 37  ? 14.404  28.064  -8.710  1.00 25.41  ? 37  MET A CG  1 
ATOM   313   S  SD  . MET A 1 37  ? 16.210  27.864  -8.518  1.00 42.90  ? 37  MET A SD  1 
ATOM   314   C  CE  . MET A 1 37  ? 16.364  27.521  -6.778  1.00 27.26  ? 37  MET A CE  1 
ATOM   315   N  N   . ALA A 1 38  ? 12.126  30.671  -9.808  1.00 24.03  ? 38  ALA A N   1 
ATOM   316   C  CA  . ALA A 1 38  ? 11.591  30.930  -11.133 1.00 25.85  ? 38  ALA A CA  1 
ATOM   317   C  C   . ALA A 1 38  ? 12.023  29.821  -12.078 1.00 21.64  ? 38  ALA A C   1 
ATOM   318   O  O   . ALA A 1 38  ? 13.184  29.416  -12.080 1.00 21.39  ? 38  ALA A O   1 
ATOM   319   C  CB  . ALA A 1 38  ? 12.060  32.291  -11.645 1.00 22.11  ? 38  ALA A CB  1 
ATOM   320   N  N   . ALA A 1 39  ? 11.072  29.323  -12.869 1.00 25.11  ? 39  ALA A N   1 
ATOM   321   C  CA  . ALA A 1 39  ? 11.336  28.191  -13.760 1.00 27.80  ? 39  ALA A CA  1 
ATOM   322   C  C   . ALA A 1 39  ? 12.456  28.468  -14.759 1.00 26.82  ? 39  ALA A C   1 
ATOM   323   O  O   . ALA A 1 39  ? 13.136  27.536  -15.207 1.00 23.90  ? 39  ALA A O   1 
ATOM   324   C  CB  . ALA A 1 39  ? 10.058  27.812  -14.509 1.00 28.85  ? 39  ALA A CB  1 
ATOM   325   N  N   . SER A 1 40  ? 12.664  29.728  -15.132 1.00 28.31  ? 40  SER A N   1 
ATOM   326   C  CA  . SER A 1 40  ? 13.706  30.031  -16.100 1.00 27.49  ? 40  SER A CA  1 
ATOM   327   C  C   . SER A 1 40  ? 15.109  29.848  -15.543 1.00 26.88  ? 40  SER A C   1 
ATOM   328   O  O   . SER A 1 40  ? 16.065  29.854  -16.324 1.00 27.05  ? 40  SER A O   1 
ATOM   329   C  CB  . SER A 1 40  ? 13.529  31.457  -16.601 1.00 29.88  ? 40  SER A CB  1 
ATOM   330   O  OG  . SER A 1 40  ? 13.580  32.361  -15.528 1.00 20.04  ? 40  SER A OG  1 
ATOM   331   N  N   . LEU A 1 41  ? 15.258  29.703  -14.227 1.00 25.51  ? 41  LEU A N   1 
ATOM   332   C  CA  . LEU A 1 41  ? 16.559  29.468  -13.608 1.00 28.21  ? 41  LEU A CA  1 
ATOM   333   C  C   . LEU A 1 41  ? 16.982  28.016  -13.673 1.00 24.81  ? 41  LEU A C   1 
ATOM   334   O  O   . LEU A 1 41  ? 18.075  27.685  -13.205 1.00 25.47  ? 41  LEU A O   1 
ATOM   335   C  CB  . LEU A 1 41  ? 16.567  29.912  -12.145 1.00 25.36  ? 41  LEU A CB  1 
ATOM   336   C  CG  . LEU A 1 41  ? 16.445  31.406  -11.928 1.00 25.03  ? 41  LEU A CG  1 
ATOM   337   C  CD1 . LEU A 1 41  ? 16.061  31.713  -10.480 1.00 24.87  ? 41  LEU A CD1 1 
ATOM   338   C  CD2 . LEU A 1 41  ? 17.777  32.025  -12.286 1.00 28.34  ? 41  LEU A CD2 1 
ATOM   339   N  N   . ILE A 1 42  ? 16.149  27.167  -14.227 1.00 25.70  ? 42  ILE A N   1 
ATOM   340   C  CA  . ILE A 1 42  ? 16.484  25.772  -14.474 1.00 26.14  ? 42  ILE A CA  1 
ATOM   341   C  C   . ILE A 1 42  ? 17.428  25.680  -15.665 1.00 25.75  ? 42  ILE A C   1 
ATOM   342   O  O   . ILE A 1 42  ? 17.223  26.325  -16.701 1.00 23.94  ? 42  ILE A O   1 
ATOM   343   C  CB  . ILE A 1 42  ? 15.196  24.967  -14.725 1.00 26.72  ? 42  ILE A CB  1 
ATOM   344   C  CG1 . ILE A 1 42  ? 14.426  24.725  -13.421 1.00 21.97  ? 42  ILE A CG1 1 
ATOM   345   C  CG2 . ILE A 1 42  ? 15.502  23.669  -15.435 1.00 26.96  ? 42  ILE A CG2 1 
ATOM   346   C  CD1 . ILE A 1 42  ? 12.943  24.667  -13.647 1.00 21.06  ? 42  ILE A CD1 1 
ATOM   347   N  N   . ASP A 1 43  ? 18.460  24.851  -15.546 1.00 27.17  ? 43  ASP A N   1 
ATOM   348   C  CA  . ASP A 1 43  ? 19.352  24.636  -16.674 1.00 27.53  ? 43  ASP A CA  1 
ATOM   349   C  C   . ASP A 1 43  ? 19.293  23.205  -17.184 1.00 30.13  ? 43  ASP A C   1 
ATOM   350   O  O   . ASP A 1 43  ? 20.220  22.756  -17.853 1.00 31.38  ? 43  ASP A O   1 
ATOM   351   C  CB  . ASP A 1 43  ? 20.787  25.007  -16.306 1.00 30.02  ? 43  ASP A CB  1 
ATOM   352   C  CG  . ASP A 1 43  ? 21.216  26.339  -16.889 1.00 34.74  ? 43  ASP A CG  1 
ATOM   353   O  OD1 . ASP A 1 43  ? 20.378  27.046  -17.505 1.00 32.75  ? 43  ASP A OD1 1 
ATOM   354   O  OD2 . ASP A 1 43  ? 22.408  26.665  -16.733 1.00 33.92  ? 43  ASP A OD2 1 
ATOM   355   N  N   . GLY A 1 44  ? 18.232  22.477  -16.882 1.00 30.24  ? 44  GLY A N   1 
ATOM   356   C  CA  . GLY A 1 44  ? 17.995  21.183  -17.491 1.00 30.33  ? 44  GLY A CA  1 
ATOM   357   C  C   . GLY A 1 44  ? 18.223  20.052  -16.503 1.00 32.55  ? 44  GLY A C   1 
ATOM   358   O  O   . GLY A 1 44  ? 18.572  20.257  -15.338 1.00 31.33  ? 44  GLY A O   1 
ATOM   359   N  N   . ILE A 1 45  ? 18.020  18.838  -17.008 1.00 28.11  ? 45  ILE A N   1 
ATOM   360   C  CA  . ILE A 1 45  ? 18.250  17.632  -16.228 1.00 29.25  ? 45  ILE A CA  1 
ATOM   361   C  C   . ILE A 1 45  ? 18.595  16.511  -17.192 1.00 26.70  ? 45  ILE A C   1 
ATOM   362   O  O   . ILE A 1 45  ? 17.761  16.101  -18.005 1.00 34.73  ? 45  ILE A O   1 
ATOM   363   C  CB  . ILE A 1 45  ? 17.021  17.283  -15.358 1.00 29.12  ? 45  ILE A CB  1 
ATOM   364   C  CG1 . ILE A 1 45  ? 17.188  15.924  -14.660 1.00 27.82  ? 45  ILE A CG1 1 
ATOM   365   C  CG2 . ILE A 1 45  ? 15.780  17.308  -16.194 1.00 22.13  ? 45  ILE A CG2 1 
ATOM   366   C  CD1 . ILE A 1 45  ? 15.948  15.464  -13.877 1.00 28.25  ? 45  ILE A CD1 1 
ATOM   367   N  N   . GLY A 1 46  ? 19.836  16.035  -17.149 1.00 32.82  ? 46  GLY A N   1 
ATOM   368   C  CA  . GLY A 1 46  ? 20.182  14.839  -17.899 1.00 30.17  ? 46  GLY A CA  1 
ATOM   369   C  C   . GLY A 1 46  ? 19.609  13.602  -17.235 1.00 34.87  ? 46  GLY A C   1 
ATOM   370   O  O   . GLY A 1 46  ? 19.476  13.530  -16.016 1.00 29.66  ? 46  GLY A O   1 
ATOM   371   N  N   . VAL A 1 47  ? 19.234  12.622  -18.049 1.00 33.34  ? 47  VAL A N   1 
ATOM   372   C  CA  . VAL A 1 47  ? 18.566  11.423  -17.554 1.00 31.77  ? 47  VAL A CA  1 
ATOM   373   C  C   . VAL A 1 47  ? 19.257  10.189  -18.122 1.00 35.83  ? 47  VAL A C   1 
ATOM   374   O  O   . VAL A 1 47  ? 19.576  10.136  -19.317 1.00 36.88  ? 47  VAL A O   1 
ATOM   375   C  CB  . VAL A 1 47  ? 17.057  11.426  -17.902 1.00 29.10  ? 47  VAL A CB  1 
ATOM   376   C  CG1 . VAL A 1 47  ? 16.352  10.269  -17.224 1.00 40.88  ? 47  VAL A CG1 1 
ATOM   377   C  CG2 . VAL A 1 47  ? 16.378  12.728  -17.460 1.00 30.15  ? 47  VAL A CG2 1 
ATOM   378   N  N   . ARG A 1 48  ? 19.457  9.178   -17.269 1.00 34.81  ? 48  ARG A N   1 
ATOM   379   C  CA  . ARG A 1 48  ? 20.061  7.930   -17.719 1.00 35.78  ? 48  ARG A CA  1 
ATOM   380   C  C   . ARG A 1 48  ? 19.460  6.730   -16.986 1.00 40.57  ? 48  ARG A C   1 
ATOM   381   O  O   . ARG A 1 48  ? 19.336  6.735   -15.755 1.00 32.65  ? 48  ARG A O   1 
ATOM   382   C  CB  . ARG A 1 48  ? 21.583  7.992   -17.533 1.00 43.84  ? 48  ARG A CB  1 
ATOM   383   C  CG  . ARG A 1 48  ? 22.353  6.729   -17.894 1.00 45.93  ? 48  ARG A CG  1 
ATOM   384   C  CD  . ARG A 1 48  ? 23.851  6.907   -17.626 1.00 51.75  ? 48  ARG A CD  1 
ATOM   385   N  NE  . ARG A 1 48  ? 24.124  7.606   -16.371 1.00 57.34  ? 48  ARG A NE  1 
ATOM   386   C  CZ  . ARG A 1 48  ? 24.648  8.825   -16.287 1.00 59.08  ? 48  ARG A CZ  1 
ATOM   387   N  NH1 . ARG A 1 48  ? 24.971  9.515   -17.374 1.00 58.02  ? 48  ARG A NH1 1 
ATOM   388   N  NH2 . ARG A 1 48  ? 24.849  9.367   -15.084 1.00 49.46  ? 48  ARG A NH2 1 
ATOM   389   N  N   . ILE A 1 49  ? 19.040  5.733   -17.763 1.00 34.11  ? 49  ILE A N   1 
ATOM   390   C  CA  . ILE A 1 49  ? 18.841  4.362   -17.313 1.00 42.00  ? 49  ILE A CA  1 
ATOM   391   C  C   . ILE A 1 49  ? 19.748  3.502   -18.187 1.00 40.49  ? 49  ILE A C   1 
ATOM   392   O  O   . ILE A 1 49  ? 19.541  3.429   -19.404 1.00 38.20  ? 49  ILE A O   1 
ATOM   393   C  CB  . ILE A 1 49  ? 17.382  3.883   -17.427 1.00 33.22  ? 49  ILE A CB  1 
ATOM   394   C  CG1 . ILE A 1 49  ? 16.426  4.760   -16.639 1.00 31.52  ? 49  ILE A CG1 1 
ATOM   395   C  CG2 . ILE A 1 49  ? 17.267  2.457   -16.961 1.00 34.07  ? 49  ILE A CG2 1 
ATOM   396   C  CD1 . ILE A 1 49  ? 15.003  4.714   -17.161 1.00 32.40  ? 49  ILE A CD1 1 
ATOM   397   N  N   . PRO A 1 50  ? 20.745  2.823   -17.621 1.00 41.35  ? 50  PRO A N   1 
ATOM   398   C  CA  . PRO A 1 50  ? 21.761  2.176   -18.458 1.00 43.02  ? 50  PRO A CA  1 
ATOM   399   C  C   . PRO A 1 50  ? 21.139  1.133   -19.374 1.00 43.18  ? 50  PRO A C   1 
ATOM   400   O  O   . PRO A 1 50  ? 20.426  0.224   -18.932 1.00 42.13  ? 50  PRO A O   1 
ATOM   401   C  CB  . PRO A 1 50  ? 22.719  1.546   -17.442 1.00 47.97  ? 50  PRO A CB  1 
ATOM   402   C  CG  . PRO A 1 50  ? 21.959  1.440   -16.174 1.00 48.17  ? 50  PRO A CG  1 
ATOM   403   C  CD  . PRO A 1 50  ? 20.776  2.358   -16.225 1.00 41.49  ? 50  PRO A CD  1 
ATOM   404   N  N   . GLY A 1 51  ? 21.391  1.298   -20.664 1.00 37.65  ? 51  GLY A N   1 
ATOM   405   C  CA  . GLY A 1 51  ? 20.899  0.397   -21.664 1.00 35.40  ? 51  GLY A CA  1 
ATOM   406   C  C   . GLY A 1 51  ? 19.525  0.713   -22.195 1.00 41.36  ? 51  GLY A C   1 
ATOM   407   O  O   . GLY A 1 51  ? 19.072  0.033   -23.126 1.00 49.75  ? 51  GLY A O   1 
ATOM   408   N  N   . LEU A 1 52  ? 18.844  1.694   -21.646 1.00 37.15  ? 52  LEU A N   1 
ATOM   409   C  CA  . LEU A 1 52  ? 17.505  2.002   -22.144 1.00 40.08  ? 52  LEU A CA  1 
ATOM   410   C  C   . LEU A 1 52  ? 17.315  3.476   -22.439 1.00 32.50  ? 52  LEU A C   1 
ATOM   411   O  O   . LEU A 1 52  ? 16.589  3.817   -23.371 1.00 31.37  ? 52  LEU A O   1 
ATOM   412   C  CB  . LEU A 1 52  ? 16.430  1.566   -21.147 1.00 36.14  ? 52  LEU A CB  1 
ATOM   413   C  CG  . LEU A 1 52  ? 16.377  0.108   -20.729 1.00 39.07  ? 52  LEU A CG  1 
ATOM   414   C  CD1 . LEU A 1 52  ? 15.802  0.007   -19.337 1.00 34.32  ? 52  LEU A CD1 1 
ATOM   415   C  CD2 . LEU A 1 52  ? 15.563  -0.732  -21.732 1.00 43.31  ? 52  LEU A CD2 1 
ATOM   416   N  N   . VAL A 1 53  ? 17.938  4.351   -21.662 1.00 39.74  ? 53  VAL A N   1 
ATOM   417   C  CA  . VAL A 1 53  ? 17.729  5.787   -21.777 1.00 39.38  ? 53  VAL A CA  1 
ATOM   418   C  C   . VAL A 1 53  ? 19.043  6.503   -21.512 1.00 35.19  ? 53  VAL A C   1 
ATOM   419   O  O   . VAL A 1 53  ? 19.761  6.180   -20.562 1.00 37.09  ? 53  VAL A O   1 
ATOM   420   C  CB  . VAL A 1 53  ? 16.633  6.268   -20.806 1.00 38.09  ? 53  VAL A CB  1 
ATOM   421   C  CG1 . VAL A 1 53  ? 16.995  7.628   -20.219 1.00 38.46  ? 53  VAL A CG1 1 
ATOM   422   C  CG2 . VAL A 1 53  ? 15.314  6.337   -21.525 1.00 40.58  ? 53  VAL A CG2 1 
ATOM   423   N  N   . ASP A 1 54  ? 19.352  7.481   -22.361 1.00 38.18  ? 54  ASP A N   1 
ATOM   424   C  CA  . ASP A 1 54  ? 20.555  8.292   -22.202 1.00 38.13  ? 54  ASP A CA  1 
ATOM   425   C  C   . ASP A 1 54  ? 20.296  9.561   -23.013 1.00 42.31  ? 54  ASP A C   1 
ATOM   426   O  O   . ASP A 1 54  ? 20.342  9.521   -24.248 1.00 37.81  ? 54  ASP A O   1 
ATOM   427   C  CB  . ASP A 1 54  ? 21.786  7.537   -22.687 1.00 44.27  ? 54  ASP A CB  1 
ATOM   428   C  CG  . ASP A 1 54  ? 23.061  8.377   -22.660 1.00 44.72  ? 54  ASP A CG  1 
ATOM   429   O  OD1 . ASP A 1 54  ? 23.530  8.716   -21.560 1.00 33.36  ? 54  ASP A OD1 1 
ATOM   430   O  OD2 . ASP A 1 54  ? 23.611  8.663   -23.751 1.00 51.66  ? 54  ASP A OD2 1 
ATOM   431   N  N   . VAL A 1 55  ? 19.955  10.653  -22.314 1.00 40.05  ? 55  VAL A N   1 
ATOM   432   C  CA  . VAL A 1 55  ? 19.622  11.928  -22.947 1.00 34.99  ? 55  VAL A CA  1 
ATOM   433   C  C   . VAL A 1 55  ? 20.310  13.063  -22.206 1.00 30.35  ? 55  VAL A C   1 
ATOM   434   O  O   . VAL A 1 55  ? 20.501  13.015  -20.986 1.00 32.33  ? 55  VAL A O   1 
ATOM   435   C  CB  . VAL A 1 55  ? 18.103  12.190  -22.994 1.00 32.61  ? 55  VAL A CB  1 
ATOM   436   C  CG1 . VAL A 1 55  ? 17.455  11.303  -24.017 1.00 33.08  ? 55  VAL A CG1 1 
ATOM   437   C  CG2 . VAL A 1 55  ? 17.484  11.968  -21.625 1.00 35.62  ? 55  VAL A CG2 1 
ATOM   438   N  N   . GLY A 1 56  ? 20.680  14.096  -22.962 1.00 32.25  ? 56  GLY A N   1 
ATOM   439   C  CA  . GLY A 1 56  ? 21.321  15.274  -22.409 1.00 33.53  ? 56  GLY A CA  1 
ATOM   440   C  C   . GLY A 1 56  ? 20.337  16.163  -21.678 1.00 33.30  ? 56  GLY A C   1 
ATOM   441   O  O   . GLY A 1 56  ? 19.114  15.956  -21.700 1.00 33.65  ? 56  GLY A O   1 
ATOM   442   N  N   . PRO A 1 57  ? 20.875  17.194  -21.014 1.00 36.94  ? 57  PRO A N   1 
ATOM   443   C  CA  . PRO A 1 57  ? 20.052  17.986  -20.085 1.00 30.78  ? 57  PRO A CA  1 
ATOM   444   C  C   . PRO A 1 57  ? 18.948  18.809  -20.734 1.00 30.68  ? 57  PRO A C   1 
ATOM   445   O  O   . PRO A 1 57  ? 18.042  19.239  -20.019 1.00 31.13  ? 57  PRO A O   1 
ATOM   446   C  CB  . PRO A 1 57  ? 21.078  18.898  -19.387 1.00 31.01  ? 57  PRO A CB  1 
ATOM   447   C  CG  . PRO A 1 57  ? 22.299  18.833  -20.192 1.00 40.87  ? 57  PRO A CG  1 
ATOM   448   C  CD  . PRO A 1 57  ? 22.306  17.533  -20.921 1.00 38.58  ? 57  PRO A CD  1 
ATOM   449   N  N   . ASP A 1 58  ? 18.979  19.062  -22.040 1.00 33.65  ? 58  ASP A N   1 
ATOM   450   C  CA  . ASP A 1 58  ? 17.973  19.912  -22.656 1.00 30.92  ? 58  ASP A CA  1 
ATOM   451   C  C   . ASP A 1 58  ? 16.834  19.127  -23.298 1.00 34.72  ? 58  ASP A C   1 
ATOM   452   O  O   . ASP A 1 58  ? 15.920  19.741  -23.863 1.00 33.00  ? 58  ASP A O   1 
ATOM   453   C  CB  . ASP A 1 58  ? 18.620  20.832  -23.697 1.00 35.36  ? 58  ASP A CB  1 
ATOM   454   C  CG  . ASP A 1 58  ? 19.625  20.113  -24.562 1.00 43.66  ? 58  ASP A CG  1 
ATOM   455   O  OD1 . ASP A 1 58  ? 20.693  19.716  -24.031 1.00 46.92  ? 58  ASP A OD1 1 
ATOM   456   O  OD2 . ASP A 1 58  ? 19.348  19.948  -25.768 1.00 47.82  ? 58  ASP A OD2 1 
ATOM   457   N  N   . VAL A 1 59  ? 16.848  17.800  -23.205 1.00 28.95  ? 59  VAL A N   1 
ATOM   458   C  CA  . VAL A 1 59  ? 15.873  16.975  -23.912 1.00 30.29  ? 59  VAL A CA  1 
ATOM   459   C  C   . VAL A 1 59  ? 14.589  16.762  -23.111 1.00 26.90  ? 59  VAL A C   1 
ATOM   460   O  O   . VAL A 1 59  ? 13.498  16.912  -23.685 1.00 27.41  ? 59  VAL A O   1 
ATOM   461   C  CB  . VAL A 1 59  ? 16.504  15.634  -24.337 1.00 32.13  ? 59  VAL A CB  1 
ATOM   462   C  CG1 . VAL A 1 59  ? 15.441  14.663  -24.770 1.00 30.28  ? 59  VAL A CG1 1 
ATOM   463   C  CG2 . VAL A 1 59  ? 17.485  15.865  -25.481 1.00 28.93  ? 59  VAL A CG2 1 
ATOM   464   N  N   . PRO A 1 60  ? 14.621  16.409  -21.820 1.00 27.06  ? 60  PRO A N   1 
ATOM   465   C  CA  . PRO A 1 60  ? 13.351  16.153  -21.124 1.00 23.49  ? 60  PRO A CA  1 
ATOM   466   C  C   . PRO A 1 60  ? 12.481  17.393  -21.049 1.00 22.97  ? 60  PRO A C   1 
ATOM   467   O  O   . PRO A 1 60  ? 12.974  18.519  -20.973 1.00 25.07  ? 60  PRO A O   1 
ATOM   468   C  CB  . PRO A 1 60  ? 13.790  15.700  -19.721 1.00 28.72  ? 60  PRO A CB  1 
ATOM   469   C  CG  . PRO A 1 60  ? 15.175  15.180  -19.895 1.00 25.98  ? 60  PRO A CG  1 
ATOM   470   C  CD  . PRO A 1 60  ? 15.776  16.088  -20.962 1.00 28.90  ? 60  PRO A CD  1 
ATOM   471   N  N   . LEU A 1 61  ? 11.167  17.170  -21.078 1.00 26.60  ? 61  LEU A N   1 
ATOM   472   C  CA  . LEU A 1 61  ? 10.182  18.225  -20.863 1.00 25.72  ? 61  LEU A CA  1 
ATOM   473   C  C   . LEU A 1 61  ? 9.793   18.322  -19.388 1.00 28.81  ? 61  LEU A C   1 
ATOM   474   O  O   . LEU A 1 61  ? 9.858   17.334  -18.632 1.00 22.77  ? 61  LEU A O   1 
ATOM   475   C  CB  . LEU A 1 61  ? 8.932   17.982  -21.699 1.00 21.16  ? 61  LEU A CB  1 
ATOM   476   C  CG  . LEU A 1 61  ? 9.139   17.680  -23.199 1.00 24.69  ? 61  LEU A CG  1 
ATOM   477   C  CD1 . LEU A 1 61  ? 7.803   17.812  -23.923 1.00 24.78  ? 61  LEU A CD1 1 
ATOM   478   C  CD2 . LEU A 1 61  ? 10.173  18.587  -23.836 1.00 27.33  ? 61  LEU A CD2 1 
ATOM   479   N  N   . TRP A 1 62  ? 9.361   19.529  -18.995 1.00 27.03  ? 62  TRP A N   1 
ATOM   480   C  CA  . TRP A 1 62  ? 9.079   19.889  -17.602 1.00 26.53  ? 62  TRP A CA  1 
ATOM   481   C  C   . TRP A 1 62  ? 7.616   20.278  -17.465 1.00 25.75  ? 62  TRP A C   1 
ATOM   482   O  O   . TRP A 1 62  ? 7.165   21.229  -18.112 1.00 23.64  ? 62  TRP A O   1 
ATOM   483   C  CB  . TRP A 1 62  ? 9.955   21.060  -17.149 1.00 24.60  ? 62  TRP A CB  1 
ATOM   484   C  CG  . TRP A 1 62  ? 11.408  20.752  -17.017 1.00 22.66  ? 62  TRP A CG  1 
ATOM   485   C  CD1 . TRP A 1 62  ? 12.290  20.483  -18.028 1.00 25.15  ? 62  TRP A CD1 1 
ATOM   486   C  CD2 . TRP A 1 62  ? 12.162  20.683  -15.794 1.00 23.74  ? 62  TRP A CD2 1 
ATOM   487   N  NE1 . TRP A 1 62  ? 13.546  20.238  -17.504 1.00 27.67  ? 62  TRP A NE1 1 
ATOM   488   C  CE2 . TRP A 1 62  ? 13.485  20.352  -16.135 1.00 25.72  ? 62  TRP A CE2 1 
ATOM   489   C  CE3 . TRP A 1 62  ? 11.839  20.856  -14.440 1.00 25.15  ? 62  TRP A CE3 1 
ATOM   490   C  CZ2 . TRP A 1 62  ? 14.490  20.220  -15.177 1.00 21.99  ? 62  TRP A CZ2 1 
ATOM   491   C  CZ3 . TRP A 1 62  ? 12.838  20.718  -13.499 1.00 23.11  ? 62  TRP A CZ3 1 
ATOM   492   C  CH2 . TRP A 1 62  ? 14.144  20.407  -13.870 1.00 25.99  ? 62  TRP A CH2 1 
ATOM   493   N  N   . THR A 1 63  ? 6.869   19.555  -16.630 1.00 25.40  ? 63  THR A N   1 
ATOM   494   C  CA  . THR A 1 63  ? 5.538   20.000  -16.247 1.00 22.23  ? 63  THR A CA  1 
ATOM   495   C  C   . THR A 1 63  ? 5.616   20.720  -14.899 1.00 19.41  ? 63  THR A C   1 
ATOM   496   O  O   . THR A 1 63  ? 5.935   20.113  -13.869 1.00 24.24  ? 63  THR A O   1 
ATOM   497   C  CB  . THR A 1 63  ? 4.528   18.855  -16.207 1.00 21.75  ? 63  THR A CB  1 
ATOM   498   O  OG1 . THR A 1 63  ? 4.419   18.272  -17.512 1.00 22.59  ? 63  THR A OG1 1 
ATOM   499   C  CG2 . THR A 1 63  ? 3.160   19.414  -15.807 1.00 19.55  ? 63  THR A CG2 1 
ATOM   500   N  N   . LEU A 1 64  ? 5.326   22.016  -14.915 1.00 25.75  ? 64  LEU A N   1 
ATOM   501   C  CA  . LEU A 1 64  ? 5.377   22.870  -13.736 1.00 20.32  ? 64  LEU A CA  1 
ATOM   502   C  C   . LEU A 1 64  ? 4.105   23.692  -13.716 1.00 27.95  ? 64  LEU A C   1 
ATOM   503   O  O   . LEU A 1 64  ? 3.689   24.217  -14.756 1.00 26.93  ? 64  LEU A O   1 
ATOM   504   C  CB  . LEU A 1 64  ? 6.605   23.795  -13.767 1.00 25.41  ? 64  LEU A CB  1 
ATOM   505   C  CG  . LEU A 1 64  ? 8.003   23.154  -13.811 1.00 22.37  ? 64  LEU A CG  1 
ATOM   506   C  CD1 . LEU A 1 64  ? 9.081   24.169  -14.158 1.00 22.20  ? 64  LEU A CD1 1 
ATOM   507   C  CD2 . LEU A 1 64  ? 8.323   22.498  -12.446 1.00 22.03  ? 64  LEU A CD2 1 
ATOM   508   N  N   . GLN A 1 65  ? 3.492   23.793  -12.541 1.00 27.53  ? 65  GLN A N   1 
ATOM   509   C  CA  . GLN A 1 65  ? 2.273   24.569  -12.352 1.00 27.89  ? 65  GLN A CA  1 
ATOM   510   C  C   . GLN A 1 65  ? 1.277   24.302  -13.487 1.00 26.45  ? 65  GLN A C   1 
ATOM   511   O  O   . GLN A 1 65  ? 0.736   25.217  -14.106 1.00 29.91  ? 65  GLN A O   1 
ATOM   512   C  CB  . GLN A 1 65  ? 2.607   26.064  -12.229 1.00 30.06  ? 65  GLN A CB  1 
ATOM   513   C  CG  . GLN A 1 65  ? 3.443   26.457  -10.966 1.00 22.84  ? 65  GLN A CG  1 
ATOM   514   C  CD  . GLN A 1 65  ? 3.797   27.960  -10.913 1.00 24.79  ? 65  GLN A CD  1 
ATOM   515   O  OE1 . GLN A 1 65  ? 4.284   28.543  -11.892 1.00 23.93  ? 65  GLN A OE1 1 
ATOM   516   N  NE2 . GLN A 1 65  ? 3.563   28.579  -9.762  1.00 18.38  ? 65  GLN A NE2 1 
ATOM   517   N  N   . GLY A 1 66  ? 1.074   23.025  -13.788 1.00 31.40  ? 66  GLY A N   1 
ATOM   518   C  CA  . GLY A 1 66  ? -0.020  22.599  -14.644 1.00 28.34  ? 66  GLY A CA  1 
ATOM   519   C  C   . GLY A 1 66  ? 0.204   22.702  -16.139 1.00 30.21  ? 66  GLY A C   1 
ATOM   520   O  O   . GLY A 1 66  ? -0.736  22.448  -16.899 1.00 38.64  ? 66  GLY A O   1 
ATOM   521   N  N   . GLN A 1 67  ? 1.407   23.060  -16.593 1.00 30.96  ? 67  GLN A N   1 
ATOM   522   C  CA  . GLN A 1 67  ? 1.720   23.174  -18.016 1.00 28.62  ? 67  GLN A CA  1 
ATOM   523   C  C   . GLN A 1 67  ? 3.061   22.513  -18.283 1.00 22.87  ? 67  GLN A C   1 
ATOM   524   O  O   . GLN A 1 67  ? 3.931   22.485  -17.415 1.00 23.87  ? 67  GLN A O   1 
ATOM   525   C  CB  . GLN A 1 67  ? 1.793   24.641  -18.462 1.00 27.26  ? 67  GLN A CB  1 
ATOM   526   C  CG  . GLN A 1 67  ? 0.463   25.300  -18.772 1.00 36.95  ? 67  GLN A CG  1 
ATOM   527   C  CD  . GLN A 1 67  ? 0.646   26.601  -19.563 1.00 36.55  ? 67  GLN A CD  1 
ATOM   528   O  OE1 . GLN A 1 67  ? 0.296   27.681  -19.090 1.00 41.05  ? 67  GLN A OE1 1 
ATOM   529   N  NE2 . GLN A 1 67  ? 1.203   26.495  -20.767 1.00 38.64  ? 67  GLN A NE2 1 
ATOM   530   N  N   . GLN A 1 68  ? 3.240   22.008  -19.499 1.00 26.69  ? 68  GLN A N   1 
ATOM   531   C  CA  . GLN A 1 68  ? 4.476   21.346  -19.884 1.00 24.03  ? 68  GLN A CA  1 
ATOM   532   C  C   . GLN A 1 68  ? 5.329   22.231  -20.795 1.00 25.60  ? 68  GLN A C   1 
ATOM   533   O  O   . GLN A 1 68  ? 4.830   22.826  -21.754 1.00 27.30  ? 68  GLN A O   1 
ATOM   534   C  CB  . GLN A 1 68  ? 4.171   20.030  -20.592 1.00 28.84  ? 68  GLN A CB  1 
ATOM   535   C  CG  . GLN A 1 68  ? 5.399   19.171  -20.836 1.00 29.39  ? 68  GLN A CG  1 
ATOM   536   C  CD  . GLN A 1 68  ? 5.035   17.821  -21.420 1.00 28.20  ? 68  GLN A CD  1 
ATOM   537   O  OE1 . GLN A 1 68  ? 4.506   17.739  -22.517 1.00 26.96  ? 68  GLN A OE1 1 
ATOM   538   N  NE2 . GLN A 1 68  ? 5.327   16.755  -20.686 1.00 28.71  ? 68  GLN A NE2 1 
ATOM   539   N  N   . TYR A 1 69  ? 6.626   22.276  -20.530 1.00 25.38  ? 69  TYR A N   1 
ATOM   540   C  CA  . TYR A 1 69  ? 7.520   23.125  -21.301 1.00 26.57  ? 69  TYR A CA  1 
ATOM   541   C  C   . TYR A 1 69  ? 8.760   22.350  -21.713 1.00 30.35  ? 69  TYR A C   1 
ATOM   542   O  O   . TYR A 1 69  ? 9.197   21.427  -21.018 1.00 27.09  ? 69  TYR A O   1 
ATOM   543   C  CB  . TYR A 1 69  ? 7.959   24.373  -20.501 1.00 24.04  ? 69  TYR A CB  1 
ATOM   544   C  CG  . TYR A 1 69  ? 6.814   25.158  -19.935 1.00 29.18  ? 69  TYR A CG  1 
ATOM   545   C  CD1 . TYR A 1 69  ? 6.215   26.180  -20.670 1.00 27.10  ? 69  TYR A CD1 1 
ATOM   546   C  CD2 . TYR A 1 69  ? 6.318   24.880  -18.654 1.00 27.11  ? 69  TYR A CD2 1 
ATOM   547   C  CE1 . TYR A 1 69  ? 5.142   26.892  -20.152 1.00 30.47  ? 69  TYR A CE1 1 
ATOM   548   C  CE2 . TYR A 1 69  ? 5.248   25.589  -18.135 1.00 28.15  ? 69  TYR A CE2 1 
ATOM   549   C  CZ  . TYR A 1 69  ? 4.664   26.591  -18.891 1.00 27.58  ? 69  TYR A CZ  1 
ATOM   550   O  OH  . TYR A 1 69  ? 3.594   27.307  -18.399 1.00 27.07  ? 69  TYR A OH  1 
ATOM   551   N  N   . THR A 1 70  ? 9.332   22.750  -22.848 1.00 26.35  ? 70  THR A N   1 
ATOM   552   C  CA  . THR A 1 70  ? 10.706  22.386  -23.155 1.00 26.27  ? 70  THR A CA  1 
ATOM   553   C  C   . THR A 1 70  ? 11.668  23.228  -22.313 1.00 23.45  ? 70  THR A C   1 
ATOM   554   O  O   . THR A 1 70  ? 11.283  24.216  -21.699 1.00 25.72  ? 70  THR A O   1 
ATOM   555   C  CB  . THR A 1 70  ? 10.984  22.577  -24.645 1.00 26.97  ? 70  THR A CB  1 
ATOM   556   O  OG1 . THR A 1 70  ? 11.075  23.972  -24.933 1.00 29.09  ? 70  THR A OG1 1 
ATOM   557   C  CG2 . THR A 1 70  ? 9.866   21.984  -25.485 1.00 24.31  ? 70  THR A CG2 1 
ATOM   558   N  N   . LEU A 1 71  ? 12.942  22.847  -22.293 1.00 23.32  ? 71  LEU A N   1 
ATOM   559   C  CA  . LEU A 1 71  ? 13.902  23.703  -21.610 1.00 25.09  ? 71  LEU A CA  1 
ATOM   560   C  C   . LEU A 1 71  ? 14.041  25.043  -22.316 1.00 28.38  ? 71  LEU A C   1 
ATOM   561   O  O   . LEU A 1 71  ? 14.222  26.076  -21.663 1.00 28.70  ? 71  LEU A O   1 
ATOM   562   C  CB  . LEU A 1 71  ? 15.267  23.035  -21.510 1.00 27.47  ? 71  LEU A CB  1 
ATOM   563   C  CG  . LEU A 1 71  ? 16.318  23.823  -20.712 1.00 25.71  ? 71  LEU A CG  1 
ATOM   564   C  CD1 . LEU A 1 71  ? 15.900  24.062  -19.234 1.00 26.94  ? 71  LEU A CD1 1 
ATOM   565   C  CD2 . LEU A 1 71  ? 17.683  23.146  -20.806 1.00 27.04  ? 71  LEU A CD2 1 
ATOM   566   N  N   . ALA A 1 72  ? 13.996  25.050  -23.651 1.00 25.64  ? 72  ALA A N   1 
ATOM   567   C  CA  . ALA A 1 72  ? 14.123  26.323  -24.353 1.00 28.27  ? 72  ALA A CA  1 
ATOM   568   C  C   . ALA A 1 72  ? 13.001  27.257  -23.930 1.00 29.89  ? 72  ALA A C   1 
ATOM   569   O  O   . ALA A 1 72  ? 13.218  28.463  -23.739 1.00 30.49  ? 72  ALA A O   1 
ATOM   570   C  CB  . ALA A 1 72  ? 14.129  26.105  -25.872 1.00 29.16  ? 72  ALA A CB  1 
ATOM   571   N  N   . GLU A 1 73  ? 11.809  26.696  -23.698 1.00 22.26  ? 73  GLU A N   1 
ATOM   572   C  CA  . GLU A 1 73  ? 10.689  27.515  -23.261 1.00 22.50  ? 73  GLU A CA  1 
ATOM   573   C  C   . GLU A 1 73  ? 10.897  28.019  -21.841 1.00 26.53  ? 73  GLU A C   1 
ATOM   574   O  O   . GLU A 1 73  ? 10.744  29.213  -21.576 1.00 30.76  ? 73  GLU A O   1 
ATOM   575   C  CB  . GLU A 1 73  ? 9.396   26.729  -23.391 1.00 24.15  ? 73  GLU A CB  1 
ATOM   576   C  CG  . GLU A 1 73  ? 8.949   26.698  -24.825 1.00 26.40  ? 73  GLU A CG  1 
ATOM   577   C  CD  . GLU A 1 73  ? 7.939   25.645  -25.095 1.00 28.17  ? 73  GLU A CD  1 
ATOM   578   O  OE1 . GLU A 1 73  ? 7.803   24.705  -24.279 1.00 33.26  ? 73  GLU A OE1 1 
ATOM   579   O  OE2 . GLU A 1 73  ? 7.267   25.757  -26.128 1.00 28.18  ? 73  GLU A OE2 1 
ATOM   580   N  N   . LEU A 1 74  ? 11.264  27.130  -20.918 1.00 24.96  ? 74  LEU A N   1 
ATOM   581   C  CA  . LEU A 1 74  ? 11.590  27.569  -19.565 1.00 24.09  ? 74  LEU A CA  1 
ATOM   582   C  C   . LEU A 1 74  ? 12.572  28.741  -19.576 1.00 26.03  ? 74  LEU A C   1 
ATOM   583   O  O   . LEU A 1 74  ? 12.388  29.720  -18.849 1.00 29.23  ? 74  LEU A O   1 
ATOM   584   C  CB  . LEU A 1 74  ? 12.153  26.399  -18.767 1.00 27.38  ? 74  LEU A CB  1 
ATOM   585   C  CG  . LEU A 1 74  ? 11.186  25.277  -18.368 1.00 26.15  ? 74  LEU A CG  1 
ATOM   586   C  CD1 . LEU A 1 74  ? 11.859  24.485  -17.278 1.00 23.33  ? 74  LEU A CD1 1 
ATOM   587   C  CD2 . LEU A 1 74  ? 9.842   25.793  -17.889 1.00 20.09  ? 74  LEU A CD2 1 
ATOM   588   N  N   . TRP A 1 75  ? 13.582  28.698  -20.445 1.00 29.53  ? 75  TRP A N   1 
ATOM   589   C  CA  . TRP A 1 75  ? 14.582  29.766  -20.447 1.00 29.81  ? 75  TRP A CA  1 
ATOM   590   C  C   . TRP A 1 75  ? 13.967  31.129  -20.758 1.00 29.26  ? 75  TRP A C   1 
ATOM   591   O  O   . TRP A 1 75  ? 14.346  32.137  -20.145 1.00 29.15  ? 75  TRP A O   1 
ATOM   592   C  CB  . TRP A 1 75  ? 15.708  29.442  -21.429 1.00 29.53  ? 75  TRP A CB  1 
ATOM   593   C  CG  . TRP A 1 75  ? 16.712  28.521  -20.810 1.00 26.04  ? 75  TRP A CG  1 
ATOM   594   C  CD1 . TRP A 1 75  ? 16.871  28.271  -19.481 1.00 28.86  ? 75  TRP A CD1 1 
ATOM   595   C  CD2 . TRP A 1 75  ? 17.687  27.731  -21.491 1.00 27.63  ? 75  TRP A CD2 1 
ATOM   596   N  NE1 . TRP A 1 75  ? 17.887  27.368  -19.285 1.00 31.22  ? 75  TRP A NE1 1 
ATOM   597   C  CE2 . TRP A 1 75  ? 18.407  27.024  -20.511 1.00 32.10  ? 75  TRP A CE2 1 
ATOM   598   C  CE3 . TRP A 1 75  ? 18.023  27.550  -22.842 1.00 28.32  ? 75  TRP A CE3 1 
ATOM   599   C  CZ2 . TRP A 1 75  ? 19.451  26.144  -20.840 1.00 30.43  ? 75  TRP A CZ2 1 
ATOM   600   C  CZ3 . TRP A 1 75  ? 19.055  26.685  -23.162 1.00 30.69  ? 75  TRP A CZ3 1 
ATOM   601   C  CH2 . TRP A 1 75  ? 19.755  25.989  -22.169 1.00 29.16  ? 75  TRP A CH2 1 
ATOM   602   N  N   . ASP A 1 76  ? 12.989  31.174  -21.662 1.00 27.50  ? 76  ASP A N   1 
ATOM   603   C  CA  . ASP A 1 76  ? 12.380  32.430  -22.080 1.00 37.07  ? 76  ASP A CA  1 
ATOM   604   C  C   . ASP A 1 76  ? 11.107  32.780  -21.318 1.00 34.15  ? 76  ASP A C   1 
ATOM   605   O  O   . ASP A 1 76  ? 10.580  33.880  -21.508 1.00 33.19  ? 76  ASP A O   1 
ATOM   606   C  CB  . ASP A 1 76  ? 12.085  32.407  -23.584 1.00 40.97  ? 76  ASP A CB  1 
ATOM   607   C  CG  . ASP A 1 76  ? 13.357  32.342  -24.431 1.00 40.72  ? 76  ASP A CG  1 
ATOM   608   O  OD1 . ASP A 1 76  ? 14.458  32.394  -23.843 1.00 48.23  ? 76  ASP A OD1 1 
ATOM   609   O  OD2 . ASP A 1 76  ? 13.263  32.259  -25.678 1.00 44.07  ? 76  ASP A OD2 1 
ATOM   610   N  N   . GLY A 1 77  ? 10.623  31.900  -20.437 1.00 31.53  ? 77  GLY A N   1 
ATOM   611   C  CA  . GLY A 1 77  ? 9.383   32.159  -19.737 1.00 27.74  ? 77  GLY A CA  1 
ATOM   612   C  C   . GLY A 1 77  ? 9.531   33.163  -18.603 1.00 26.39  ? 77  GLY A C   1 
ATOM   613   O  O   . GLY A 1 77  ? 10.599  33.345  -18.033 1.00 30.92  ? 77  GLY A O   1 
ATOM   614   N  N   . ASP A 1 78  ? 8.420   33.823  -18.274 1.00 26.49  ? 78  ASP A N   1 
ATOM   615   C  CA  . ASP A 1 78  ? 8.308   34.724  -17.130 1.00 29.78  ? 78  ASP A CA  1 
ATOM   616   C  C   . ASP A 1 78  ? 7.127   34.276  -16.276 1.00 32.06  ? 78  ASP A C   1 
ATOM   617   O  O   . ASP A 1 78  ? 6.076   33.899  -16.805 1.00 30.72  ? 78  ASP A O   1 
ATOM   618   C  CB  . ASP A 1 78  ? 8.077   36.181  -17.583 1.00 36.07  ? 78  ASP A CB  1 
ATOM   619   C  CG  . ASP A 1 78  ? 9.357   37.011  -17.627 1.00 38.18  ? 78  ASP A CG  1 
ATOM   620   O  OD1 . ASP A 1 78  ? 10.047  37.140  -16.606 1.00 38.31  ? 78  ASP A OD1 1 
ATOM   621   O  OD2 . ASP A 1 78  ? 9.683   37.528  -18.716 1.00 49.72  ? 78  ASP A OD2 1 
ATOM   622   N  N   . GLY A 1 79  ? 7.286   34.326  -14.957 1.00 33.05  ? 79  GLY A N   1 
ATOM   623   C  CA  . GLY A 1 79  ? 6.178   34.062  -14.069 1.00 28.34  ? 79  GLY A CA  1 
ATOM   624   C  C   . GLY A 1 79  ? 5.987   32.613  -13.683 1.00 29.56  ? 79  GLY A C   1 
ATOM   625   O  O   . GLY A 1 79  ? 5.298   32.343  -12.698 1.00 29.70  ? 79  GLY A O   1 
ATOM   626   N  N   . VAL A 1 80  ? 6.570   31.677  -14.443 1.00 27.54  ? 80  VAL A N   1 
ATOM   627   C  CA  . VAL A 1 80  ? 6.478   30.250  -14.161 1.00 30.10  ? 80  VAL A CA  1 
ATOM   628   C  C   . VAL A 1 80  ? 7.490   29.885  -13.082 1.00 28.16  ? 80  VAL A C   1 
ATOM   629   O  O   . VAL A 1 80  ? 8.640   30.346  -13.108 1.00 25.48  ? 80  VAL A O   1 
ATOM   630   C  CB  . VAL A 1 80  ? 6.720   29.424  -15.447 1.00 25.91  ? 80  VAL A CB  1 
ATOM   631   C  CG1 . VAL A 1 80  ? 6.438   27.937  -15.181 1.00 28.74  ? 80  VAL A CG1 1 
ATOM   632   C  CG2 . VAL A 1 80  ? 5.866   29.934  -16.587 1.00 26.58  ? 80  VAL A CG2 1 
ATOM   633   N  N   . ARG A 1 81  ? 7.081   29.034  -12.140 1.00 22.95  ? 81  ARG A N   1 
ATOM   634   C  CA  . ARG A 1 81  ? 7.935   28.663  -11.024 1.00 24.72  ? 81  ARG A CA  1 
ATOM   635   C  C   . ARG A 1 81  ? 8.029   27.154  -10.871 1.00 26.20  ? 81  ARG A C   1 
ATOM   636   O  O   . ARG A 1 81  ? 7.122   26.409  -11.248 1.00 28.85  ? 81  ARG A O   1 
ATOM   637   C  CB  . ARG A 1 81  ? 7.435   29.277  -9.686  1.00 22.24  ? 81  ARG A CB  1 
ATOM   638   C  CG  . ARG A 1 81  ? 7.454   30.781  -9.684  1.00 22.82  ? 81  ARG A CG  1 
ATOM   639   C  CD  . ARG A 1 81  ? 7.027   31.410  -8.329  1.00 25.86  ? 81  ARG A CD  1 
ATOM   640   N  NE  . ARG A 1 81  ? 7.607   30.756  -7.148  1.00 29.18  ? 81  ARG A NE  1 
ATOM   641   C  CZ  . ARG A 1 81  ? 8.855   30.927  -6.734  1.00 24.28  ? 81  ARG A CZ  1 
ATOM   642   N  NH1 . ARG A 1 81  ? 9.721   31.632  -7.441  1.00 21.13  ? 81  ARG A NH1 1 
ATOM   643   N  NH2 . ARG A 1 81  ? 9.240   30.391  -5.576  1.00 24.16  ? 81  ARG A NH2 1 
ATOM   644   N  N   . TRP A 1 82  ? 9.141   26.718  -10.296 1.00 31.77  ? 82  TRP A N   1 
ATOM   645   C  CA  . TRP A 1 82  ? 9.231   25.397  -9.680  1.00 25.10  ? 82  TRP A CA  1 
ATOM   646   C  C   . TRP A 1 82  ? 9.021   25.584  -8.181  1.00 23.84  ? 82  TRP A C   1 
ATOM   647   O  O   . TRP A 1 82  ? 9.991   25.751  -7.431  1.00 25.48  ? 82  TRP A O   1 
ATOM   648   C  CB  . TRP A 1 82  ? 10.581  24.749  -9.983  1.00 23.36  ? 82  TRP A CB  1 
ATOM   649   C  CG  . TRP A 1 82  ? 10.716  23.342  -9.441  1.00 26.00  ? 82  TRP A CG  1 
ATOM   650   C  CD1 . TRP A 1 82  ? 9.792   22.652  -8.715  1.00 22.43  ? 82  TRP A CD1 1 
ATOM   651   C  CD2 . TRP A 1 82  ? 11.851  22.484  -9.558  1.00 19.99  ? 82  TRP A CD2 1 
ATOM   652   N  NE1 . TRP A 1 82  ? 10.280  21.416  -8.376  1.00 23.76  ? 82  TRP A NE1 1 
ATOM   653   C  CE2 . TRP A 1 82  ? 11.537  21.282  -8.895  1.00 23.57  ? 82  TRP A CE2 1 
ATOM   654   C  CE3 . TRP A 1 82  ? 13.097  22.610  -10.164 1.00 26.58  ? 82  TRP A CE3 1 
ATOM   655   C  CZ2 . TRP A 1 82  ? 12.414  20.223  -8.826  1.00 22.72  ? 82  TRP A CZ2 1 
ATOM   656   C  CZ3 . TRP A 1 82  ? 13.968  21.549  -10.103 1.00 23.45  ? 82  TRP A CZ3 1 
ATOM   657   C  CH2 . TRP A 1 82  ? 13.627  20.371  -9.426  1.00 26.28  ? 82  TRP A CH2 1 
ATOM   658   N  N   . PRO A 1 83  ? 7.772   25.593  -7.718  1.00 25.03  ? 83  PRO A N   1 
ATOM   659   C  CA  . PRO A 1 83  ? 7.502   25.830  -6.290  1.00 19.64  ? 83  PRO A CA  1 
ATOM   660   C  C   . PRO A 1 83  ? 8.045   24.713  -5.414  1.00 21.94  ? 83  PRO A C   1 
ATOM   661   O  O   . PRO A 1 83  ? 7.959   23.531  -5.761  1.00 23.80  ? 83  PRO A O   1 
ATOM   662   C  CB  . PRO A 1 83  ? 5.963   25.881  -6.205  1.00 24.43  ? 83  PRO A CB  1 
ATOM   663   C  CG  . PRO A 1 83  ? 5.458   25.860  -7.666  1.00 27.79  ? 83  PRO A CG  1 
ATOM   664   C  CD  . PRO A 1 83  ? 6.560   25.246  -8.475  1.00 29.37  ? 83  PRO A CD  1 
ATOM   665   N  N   . LEU A 1 84  ? 8.568   25.111  -4.247  1.00 23.55  ? 84  LEU A N   1 
ATOM   666   C  CA  . LEU A 1 84  ? 9.209   24.166  -3.340  1.00 21.67  ? 84  LEU A CA  1 
ATOM   667   C  C   . LEU A 1 84  ? 8.263   23.039  -2.976  1.00 25.33  ? 84  LEU A C   1 
ATOM   668   O  O   . LEU A 1 84  ? 8.677   21.876  -2.886  1.00 25.91  ? 84  LEU A O   1 
ATOM   669   C  CB  . LEU A 1 84  ? 9.664   24.885  -2.073  1.00 20.63  ? 84  LEU A CB  1 
ATOM   670   C  CG  . LEU A 1 84  ? 10.398  23.980  -1.096  1.00 23.09  ? 84  LEU A CG  1 
ATOM   671   C  CD1 . LEU A 1 84  ? 11.693  23.439  -1.728  1.00 16.62  ? 84  LEU A CD1 1 
ATOM   672   C  CD2 . LEU A 1 84  ? 10.668  24.662  0.233   1.00 24.23  ? 84  LEU A CD2 1 
ATOM   673   N  N   . GLU A 1 85  ? 6.978   23.357  -2.817  1.00 23.94  ? 85  GLU A N   1 
ATOM   674   C  CA  . GLU A 1 85  ? 6.008   22.360  -2.399  1.00 25.64  ? 85  GLU A CA  1 
ATOM   675   C  C   . GLU A 1 85  ? 5.625   21.359  -3.491  1.00 25.73  ? 85  GLU A C   1 
ATOM   676   O  O   . GLU A 1 85  ? 4.917   20.395  -3.180  1.00 23.78  ? 85  GLU A O   1 
ATOM   677   C  CB  . GLU A 1 85  ? 4.749   23.048  -1.869  1.00 27.06  ? 85  GLU A CB  1 
ATOM   678   C  CG  . GLU A 1 85  ? 3.907   23.761  -2.900  1.00 26.43  ? 85  GLU A CG  1 
ATOM   679   C  CD  . GLU A 1 85  ? 4.272   25.248  -3.065  1.00 24.05  ? 85  GLU A CD  1 
ATOM   680   O  OE1 . GLU A 1 85  ? 5.404   25.662  -2.726  1.00 20.58  ? 85  GLU A OE1 1 
ATOM   681   O  OE2 . GLU A 1 85  ? 3.398   26.006  -3.535  1.00 25.13  ? 85  GLU A OE2 1 
ATOM   682   N  N   . ASP A 1 86  ? 6.053   21.541  -4.742  1.00 22.95  ? 86  ASP A N   1 
ATOM   683   C  CA  . ASP A 1 86  ? 5.750   20.588  -5.809  1.00 24.17  ? 86  ASP A CA  1 
ATOM   684   C  C   . ASP A 1 86  ? 7.013   19.893  -6.297  1.00 25.46  ? 86  ASP A C   1 
ATOM   685   O  O   . ASP A 1 86  ? 8.028   20.546  -6.572  1.00 28.29  ? 86  ASP A O   1 
ATOM   686   C  CB  . ASP A 1 86  ? 5.122   21.255  -7.040  1.00 27.39  ? 86  ASP A CB  1 
ATOM   687   C  CG  . ASP A 1 86  ? 3.819   21.946  -6.747  1.00 34.10  ? 86  ASP A CG  1 
ATOM   688   O  OD1 . ASP A 1 86  ? 3.143   21.592  -5.752  1.00 36.07  ? 86  ASP A OD1 1 
ATOM   689   O  OD2 . ASP A 1 86  ? 3.490   22.868  -7.526  1.00 32.06  ? 86  ASP A OD2 1 
ATOM   690   N  N   . ALA A 1 87  ? 6.930   18.583  -6.486  1.00 22.00  ? 87  ALA A N   1 
ATOM   691   C  CA  . ALA A 1 87  ? 7.944   17.910  -7.294  1.00 24.62  ? 87  ALA A CA  1 
ATOM   692   C  C   . ALA A 1 87  ? 7.832   18.332  -8.755  1.00 24.04  ? 87  ALA A C   1 
ATOM   693   O  O   . ALA A 1 87  ? 6.729   18.482  -9.297  1.00 22.00  ? 87  ALA A O   1 
ATOM   694   C  CB  . ALA A 1 87  ? 7.799   16.397  -7.212  1.00 28.83  ? 87  ALA A CB  1 
ATOM   695   N  N   . ALA A 1 88  ? 8.978   18.510  -9.402  1.00 21.23  ? 88  ALA A N   1 
ATOM   696   C  CA  . ALA A 1 88  ? 8.948   18.723  -10.841 1.00 26.01  ? 88  ALA A CA  1 
ATOM   697   C  C   . ALA A 1 88  ? 8.633   17.416  -11.551 1.00 26.20  ? 88  ALA A C   1 
ATOM   698   O  O   . ALA A 1 88  ? 9.196   16.366  -11.231 1.00 28.33  ? 88  ALA A O   1 
ATOM   699   C  CB  . ALA A 1 88  ? 10.280  19.270  -11.330 1.00 26.22  ? 88  ALA A CB  1 
ATOM   700   N  N   . ILE A 1 89  ? 7.746   17.486  -12.533 1.00 23.74  ? 89  ILE A N   1 
ATOM   701   C  CA  . ILE A 1 89  ? 7.352   16.325  -13.312 1.00 27.61  ? 89  ILE A CA  1 
ATOM   702   C  C   . ILE A 1 89  ? 8.184   16.311  -14.591 1.00 28.18  ? 89  ILE A C   1 
ATOM   703   O  O   . ILE A 1 89  ? 7.982   17.136  -15.489 1.00 25.33  ? 89  ILE A O   1 
ATOM   704   C  CB  . ILE A 1 89  ? 5.846   16.342  -13.603 1.00 22.79  ? 89  ILE A CB  1 
ATOM   705   C  CG1 . ILE A 1 89  ? 5.063   16.406  -12.288 1.00 23.85  ? 89  ILE A CG1 1 
ATOM   706   C  CG2 . ILE A 1 89  ? 5.462   15.144  -14.447 1.00 27.33  ? 89  ILE A CG2 1 
ATOM   707   C  CD1 . ILE A 1 89  ? 3.597   16.706  -12.461 1.00 24.37  ? 89  ILE A CD1 1 
ATOM   708   N  N   . ILE A 1 90  ? 9.118   15.374  -14.677 1.00 30.47  ? 90  ILE A N   1 
ATOM   709   C  CA  . ILE A 1 90  ? 10.035  15.260  -15.808 1.00 27.21  ? 90  ILE A CA  1 
ATOM   710   C  C   . ILE A 1 90  ? 9.509   14.189  -16.753 1.00 29.29  ? 90  ILE A C   1 
ATOM   711   O  O   . ILE A 1 90  ? 9.339   13.030  -16.356 1.00 27.43  ? 90  ILE A O   1 
ATOM   712   C  CB  . ILE A 1 90  ? 11.458  14.901  -15.345 1.00 26.83  ? 90  ILE A CB  1 
ATOM   713   C  CG1 . ILE A 1 90  ? 11.967  15.867  -14.278 1.00 23.52  ? 90  ILE A CG1 1 
ATOM   714   C  CG2 . ILE A 1 90  ? 12.404  14.775  -16.534 1.00 21.98  ? 90  ILE A CG2 1 
ATOM   715   C  CD1 . ILE A 1 90  ? 11.855  17.318  -14.666 1.00 27.31  ? 90  ILE A CD1 1 
ATOM   716   N  N   . PHE A 1 91  ? 9.295   14.555  -18.008 1.00 25.25  ? 91  PHE A N   1 
ATOM   717   C  CA  . PHE A 1 91  ? 8.857   13.618  -19.034 1.00 28.52  ? 91  PHE A CA  1 
ATOM   718   C  C   . PHE A 1 91  ? 10.012  13.385  -19.997 1.00 29.89  ? 91  PHE A C   1 
ATOM   719   O  O   . PHE A 1 91  ? 10.672  14.338  -20.429 1.00 32.41  ? 91  PHE A O   1 
ATOM   720   C  CB  . PHE A 1 91  ? 7.605   14.141  -19.750 1.00 24.58  ? 91  PHE A CB  1 
ATOM   721   C  CG  . PHE A 1 91  ? 7.300   13.452  -21.039 1.00 29.05  ? 91  PHE A CG  1 
ATOM   722   C  CD1 . PHE A 1 91  ? 6.579   12.279  -21.053 1.00 29.77  ? 91  PHE A CD1 1 
ATOM   723   C  CD2 . PHE A 1 91  ? 7.702   14.006  -22.244 1.00 29.24  ? 91  PHE A CD2 1 
ATOM   724   C  CE1 . PHE A 1 91  ? 6.287   11.645  -22.217 1.00 28.69  ? 91  PHE A CE1 1 
ATOM   725   C  CE2 . PHE A 1 91  ? 7.416   13.379  -23.425 1.00 32.58  ? 91  PHE A CE2 1 
ATOM   726   C  CZ  . PHE A 1 91  ? 6.699   12.181  -23.407 1.00 34.36  ? 91  PHE A CZ  1 
ATOM   727   N  N   . VAL A 1 92  ? 10.285  12.123  -20.292 1.00 31.46  ? 92  VAL A N   1 
ATOM   728   C  CA  . VAL A 1 92  ? 11.356  11.737  -21.204 1.00 33.59  ? 92  VAL A CA  1 
ATOM   729   C  C   . VAL A 1 92  ? 10.718  11.100  -22.433 1.00 32.36  ? 92  VAL A C   1 
ATOM   730   O  O   . VAL A 1 92  ? 10.010  10.091  -22.301 1.00 32.72  ? 92  VAL A O   1 
ATOM   731   C  CB  . VAL A 1 92  ? 12.353  10.774  -20.548 1.00 33.48  ? 92  VAL A CB  1 
ATOM   732   C  CG1 . VAL A 1 92  ? 13.192  10.106  -21.617 1.00 36.49  ? 92  VAL A CG1 1 
ATOM   733   C  CG2 . VAL A 1 92  ? 13.239  11.507  -19.570 1.00 29.49  ? 92  VAL A CG2 1 
ATOM   734   N  N   . PRO A 1 93  ? 10.915  11.659  -23.628 1.00 28.51  ? 93  PRO A N   1 
ATOM   735   C  CA  . PRO A 1 93  ? 10.341  11.072  -24.854 1.00 34.66  ? 93  PRO A CA  1 
ATOM   736   C  C   . PRO A 1 93  ? 10.951  9.706   -25.123 1.00 33.72  ? 93  PRO A C   1 
ATOM   737   O  O   . PRO A 1 93  ? 12.170  9.572   -25.201 1.00 34.00  ? 93  PRO A O   1 
ATOM   738   C  CB  . PRO A 1 93  ? 10.724  12.083  -25.947 1.00 34.20  ? 93  PRO A CB  1 
ATOM   739   C  CG  . PRO A 1 93  ? 10.939  13.374  -25.224 1.00 34.07  ? 93  PRO A CG  1 
ATOM   740   C  CD  . PRO A 1 93  ? 11.500  12.991  -23.865 1.00 35.35  ? 93  PRO A CD  1 
ATOM   741   N  N   . LEU A 1 94  ? 10.099  8.685   -25.240 1.00 33.86  ? 94  LEU A N   1 
ATOM   742   C  CA  . LEU A 1 94  ? 10.587  7.331   -25.478 1.00 35.45  ? 94  LEU A CA  1 
ATOM   743   C  C   . LEU A 1 94  ? 9.442   6.484   -25.993 1.00 37.26  ? 94  LEU A C   1 
ATOM   744   O  O   . LEU A 1 94  ? 8.693   5.898   -25.202 1.00 35.10  ? 94  LEU A O   1 
ATOM   745   C  CB  . LEU A 1 94  ? 11.159  6.696   -24.217 1.00 35.76  ? 94  LEU A CB  1 
ATOM   746   C  CG  . LEU A 1 94  ? 11.810  5.339   -24.471 1.00 35.39  ? 94  LEU A CG  1 
ATOM   747   C  CD1 . LEU A 1 94  ? 12.867  5.474   -25.560 1.00 33.89  ? 94  LEU A CD1 1 
ATOM   748   C  CD2 . LEU A 1 94  ? 12.416  4.766   -23.192 1.00 34.13  ? 94  LEU A CD2 1 
ATOM   749   N  N   . PRO A 1 95  ? 9.257   6.417   -27.305 1.00 39.24  ? 95  PRO A N   1 
ATOM   750   C  CA  . PRO A 1 95  ? 8.100   5.690   -27.842 1.00 35.89  ? 95  PRO A CA  1 
ATOM   751   C  C   . PRO A 1 95  ? 8.116   4.245   -27.371 1.00 32.46  ? 95  PRO A C   1 
ATOM   752   O  O   . PRO A 1 95  ? 9.165   3.603   -27.315 1.00 33.39  ? 95  PRO A O   1 
ATOM   753   C  CB  . PRO A 1 95  ? 8.278   5.803   -29.361 1.00 39.88  ? 95  PRO A CB  1 
ATOM   754   C  CG  . PRO A 1 95  ? 9.194   6.972   -29.567 1.00 35.20  ? 95  PRO A CG  1 
ATOM   755   C  CD  . PRO A 1 95  ? 10.059  7.085   -28.345 1.00 35.76  ? 95  PRO A CD  1 
ATOM   756   N  N   . GLY A 1 96  ? 6.943   3.754   -26.979 1.00 32.98  ? 96  GLY A N   1 
ATOM   757   C  CA  . GLY A 1 96  ? 6.870   2.452   -26.350 1.00 39.03  ? 96  GLY A CA  1 
ATOM   758   C  C   . GLY A 1 96  ? 7.156   2.496   -24.860 1.00 36.90  ? 96  GLY A C   1 
ATOM   759   O  O   . GLY A 1 96  ? 6.650   1.657   -24.101 1.00 35.25  ? 96  GLY A O   1 
ATOM   760   N  N   . GLY A 1 97  ? 7.983   3.448   -24.428 1.00 32.64  ? 97  GLY A N   1 
ATOM   761   C  CA  . GLY A 1 97  ? 8.187   3.636   -23.001 1.00 34.44  ? 97  GLY A CA  1 
ATOM   762   C  C   . GLY A 1 97  ? 9.261   2.730   -22.419 1.00 33.62  ? 97  GLY A C   1 
ATOM   763   O  O   . GLY A 1 97  ? 10.271  2.428   -23.054 1.00 36.57  ? 97  GLY A O   1 
ATOM   764   N  N   . LEU A 1 98  ? 9.036   2.313   -21.164 1.00 34.81  ? 98  LEU A N   1 
ATOM   765   C  CA  . LEU A 1 98  ? 9.952   1.495   -20.381 1.00 29.15  ? 98  LEU A CA  1 
ATOM   766   C  C   . LEU A 1 98  ? 9.278   0.193   -19.968 1.00 32.98  ? 98  LEU A C   1 
ATOM   767   O  O   . LEU A 1 98  ? 8.078   0.188   -19.652 1.00 31.41  ? 98  LEU A O   1 
ATOM   768   C  CB  . LEU A 1 98  ? 10.410  2.234   -19.109 1.00 31.37  ? 98  LEU A CB  1 
ATOM   769   C  CG  . LEU A 1 98  ? 11.324  3.455   -19.164 1.00 31.38  ? 98  LEU A CG  1 
ATOM   770   C  CD1 . LEU A 1 98  ? 11.378  4.076   -17.775 1.00 31.44  ? 98  LEU A CD1 1 
ATOM   771   C  CD2 . LEU A 1 98  ? 12.712  3.088   -19.668 1.00 24.75  ? 98  LEU A CD2 1 
ATOM   772   N  N   . PRO A 1 99  ? 10.018  -0.915  -19.917 1.00 34.34  ? 99  PRO A N   1 
ATOM   773   C  CA  . PRO A 1 99  ? 9.409   -2.176  -19.489 1.00 27.63  ? 99  PRO A CA  1 
ATOM   774   C  C   . PRO A 1 99  ? 9.118   -2.160  -18.002 1.00 31.67  ? 99  PRO A C   1 
ATOM   775   O  O   . PRO A 1 99  ? 9.755   -1.442  -17.232 1.00 34.39  ? 99  PRO A O   1 
ATOM   776   C  CB  . PRO A 1 99  ? 10.479  -3.213  -19.822 1.00 33.77  ? 99  PRO A CB  1 
ATOM   777   C  CG  . PRO A 1 99  ? 11.774  -2.435  -19.686 1.00 29.73  ? 99  PRO A CG  1 
ATOM   778   C  CD  . PRO A 1 99  ? 11.455  -1.064  -20.206 1.00 29.39  ? 99  PRO A CD  1 
ATOM   779   N  N   . ASP A 1 100 ? 8.128   -2.959  -17.606 1.00 26.22  ? 100 ASP A N   1 
ATOM   780   C  CA  . ASP A 1 100 ? 7.855   -3.185  -16.195 1.00 28.18  ? 100 ASP A CA  1 
ATOM   781   C  C   . ASP A 1 100 ? 9.133   -3.484  -15.415 1.00 33.00  ? 100 ASP A C   1 
ATOM   782   O  O   . ASP A 1 100 ? 10.017  -4.198  -15.889 1.00 29.84  ? 100 ASP A O   1 
ATOM   783   C  CB  . ASP A 1 100 ? 6.886   -4.357  -16.051 1.00 33.43  ? 100 ASP A CB  1 
ATOM   784   C  CG  . ASP A 1 100 ? 5.492   -3.911  -15.806 1.00 31.99  ? 100 ASP A CG  1 
ATOM   785   O  OD1 . ASP A 1 100 ? 5.293   -2.700  -15.549 1.00 37.26  ? 100 ASP A OD1 1 
ATOM   786   O  OD2 . ASP A 1 100 ? 4.601   -4.761  -15.853 1.00 26.93  ? 100 ASP A OD2 1 
ATOM   787   N  N   . GLY A 1 101 ? 9.226   -2.955  -14.202 1.00 34.68  ? 101 GLY A N   1 
ATOM   788   C  CA  . GLY A 1 101 ? 10.247  -3.425  -13.292 1.00 35.06  ? 101 GLY A CA  1 
ATOM   789   C  C   . GLY A 1 101 ? 10.859  -2.303  -12.487 1.00 33.21  ? 101 GLY A C   1 
ATOM   790   O  O   . GLY A 1 101 ? 10.313  -1.202  -12.401 1.00 27.96  ? 101 GLY A O   1 
ATOM   791   N  N   . VAL A 1 102 ? 12.005  -2.635  -11.859 1.00 29.46  ? 102 VAL A N   1 
ATOM   792   C  CA  . VAL A 1 102 ? 12.862  -1.699  -11.141 1.00 30.44  ? 102 VAL A CA  1 
ATOM   793   C  C   . VAL A 1 102 ? 13.938  -1.237  -12.101 1.00 32.76  ? 102 VAL A C   1 
ATOM   794   O  O   . VAL A 1 102 ? 14.483  -2.044  -12.860 1.00 33.18  ? 102 VAL A O   1 
ATOM   795   C  CB  . VAL A 1 102 ? 13.490  -2.343  -9.889  1.00 29.07  ? 102 VAL A CB  1 
ATOM   796   C  CG1 . VAL A 1 102 ? 14.314  -1.312  -9.123  1.00 35.07  ? 102 VAL A CG1 1 
ATOM   797   C  CG2 . VAL A 1 102 ? 12.421  -2.924  -8.993  1.00 29.44  ? 102 VAL A CG2 1 
ATOM   798   N  N   . HIS A 1 103 ? 14.235  0.065   -12.076 1.00 32.60  ? 103 HIS A N   1 
ATOM   799   C  CA  . HIS A 1 103 ? 15.165  0.695   -13.011 1.00 33.65  ? 103 HIS A CA  1 
ATOM   800   C  C   . HIS A 1 103 ? 16.110  1.600   -12.242 1.00 30.78  ? 103 HIS A C   1 
ATOM   801   O  O   . HIS A 1 103 ? 15.662  2.428   -11.443 1.00 34.21  ? 103 HIS A O   1 
ATOM   802   C  CB  . HIS A 1 103 ? 14.436  1.531   -14.070 1.00 31.79  ? 103 HIS A CB  1 
ATOM   803   C  CG  . HIS A 1 103 ? 13.636  0.730   -15.048 1.00 33.42  ? 103 HIS A CG  1 
ATOM   804   N  ND1 . HIS A 1 103 ? 14.190  0.158   -16.173 1.00 34.55  ? 103 HIS A ND1 1 
ATOM   805   C  CD2 . HIS A 1 103 ? 12.312  0.439   -15.090 1.00 33.91  ? 103 HIS A CD2 1 
ATOM   806   C  CE1 . HIS A 1 103 ? 13.245  -0.464  -16.859 1.00 37.90  ? 103 HIS A CE1 1 
ATOM   807   N  NE2 . HIS A 1 103 ? 12.096  -0.314  -16.221 1.00 33.59  ? 103 HIS A NE2 1 
ATOM   808   N  N   . GLU A 1 104 ? 17.403  1.460   -12.497 1.00 26.46  ? 104 GLU A N   1 
ATOM   809   C  CA  . GLU A 1 104 ? 18.395  2.335   -11.889 1.00 33.80  ? 104 GLU A CA  1 
ATOM   810   C  C   . GLU A 1 104 ? 18.404  3.655   -12.654 1.00 35.24  ? 104 GLU A C   1 
ATOM   811   O  O   . GLU A 1 104 ? 18.889  3.717   -13.786 1.00 33.14  ? 104 GLU A O   1 
ATOM   812   C  CB  . GLU A 1 104 ? 19.768  1.668   -11.900 1.00 37.73  ? 104 GLU A CB  1 
ATOM   813   C  CG  . GLU A 1 104 ? 20.942  2.603   -11.597 1.00 35.92  ? 104 GLU A CG  1 
ATOM   814   C  CD  . GLU A 1 104 ? 22.286  1.961   -11.884 1.00 39.79  ? 104 GLU A CD  1 
ATOM   815   O  OE1 . GLU A 1 104 ? 22.802  1.264   -10.997 1.00 42.45  ? 104 GLU A OE1 1 
ATOM   816   O  OE2 . GLU A 1 104 ? 22.825  2.144   -12.996 1.00 48.24  ? 104 GLU A OE2 1 
ATOM   817   N  N   . LEU A 1 105 ? 17.865  4.708   -12.040 1.00 34.90  ? 105 LEU A N   1 
ATOM   818   C  CA  . LEU A 1 105 ? 17.653  5.990   -12.699 1.00 31.18  ? 105 LEU A CA  1 
ATOM   819   C  C   . LEU A 1 105 ? 18.662  7.011   -12.193 1.00 35.63  ? 105 LEU A C   1 
ATOM   820   O  O   . LEU A 1 105 ? 18.795  7.217   -10.979 1.00 34.48  ? 105 LEU A O   1 
ATOM   821   C  CB  . LEU A 1 105 ? 16.225  6.483   -12.470 1.00 30.74  ? 105 LEU A CB  1 
ATOM   822   C  CG  . LEU A 1 105 ? 15.751  7.878   -12.891 1.00 31.02  ? 105 LEU A CG  1 
ATOM   823   C  CD1 . LEU A 1 105 ? 16.228  8.246   -14.272 1.00 30.41  ? 105 LEU A CD1 1 
ATOM   824   C  CD2 . LEU A 1 105 ? 14.221  7.883   -12.847 1.00 26.85  ? 105 LEU A CD2 1 
ATOM   825   N  N   . SER A 1 106 ? 19.360  7.648   -13.132 1.00 31.95  ? 106 SER A N   1 
ATOM   826   C  CA  . SER A 1 106 ? 20.419  8.606   -12.848 1.00 36.74  ? 106 SER A CA  1 
ATOM   827   C  C   . SER A 1 106 ? 20.075  9.935   -13.503 1.00 31.25  ? 106 SER A C   1 
ATOM   828   O  O   . SER A 1 106 ? 19.788  9.984   -14.704 1.00 32.33  ? 106 SER A O   1 
ATOM   829   C  CB  . SER A 1 106 ? 21.769  8.090   -13.352 1.00 38.86  ? 106 SER A CB  1 
ATOM   830   O  OG  . SER A 1 106 ? 22.217  7.016   -12.544 1.00 40.51  ? 106 SER A OG  1 
ATOM   831   N  N   . ILE A 1 107 ? 20.087  11.002  -12.710 1.00 30.13  ? 107 ILE A N   1 
ATOM   832   C  CA  . ILE A 1 107 ? 19.729  12.331  -13.184 1.00 29.21  ? 107 ILE A CA  1 
ATOM   833   C  C   . ILE A 1 107 ? 20.892  13.276  -12.922 1.00 30.29  ? 107 ILE A C   1 
ATOM   834   O  O   . ILE A 1 107 ? 21.671  13.088  -11.982 1.00 36.69  ? 107 ILE A O   1 
ATOM   835   C  CB  . ILE A 1 107 ? 18.428  12.862  -12.525 1.00 30.19  ? 107 ILE A CB  1 
ATOM   836   C  CG1 . ILE A 1 107 ? 18.637  13.155  -11.040 1.00 31.38  ? 107 ILE A CG1 1 
ATOM   837   C  CG2 . ILE A 1 107 ? 17.269  11.900  -12.739 1.00 31.12  ? 107 ILE A CG2 1 
ATOM   838   C  CD1 . ILE A 1 107 ? 17.505  13.979  -10.410 1.00 34.76  ? 107 ILE A CD1 1 
ATOM   839   N  N   . GLU A 1 108 ? 21.018  14.294  -13.768 1.00 31.13  ? 108 GLU A N   1 
ATOM   840   C  CA  . GLU A 1 108 ? 21.971  15.390  -13.547 1.00 31.96  ? 108 GLU A CA  1 
ATOM   841   C  C   . GLU A 1 108 ? 21.179  16.684  -13.668 1.00 30.46  ? 108 GLU A C   1 
ATOM   842   O  O   . GLU A 1 108 ? 20.841  17.112  -14.773 1.00 32.58  ? 108 GLU A O   1 
ATOM   843   C  CB  . GLU A 1 108 ? 23.149  15.349  -14.528 1.00 39.37  ? 108 GLU A CB  1 
ATOM   844   C  CG  . GLU A 1 108 ? 24.286  16.353  -14.201 1.00 40.00  ? 108 GLU A CG  1 
ATOM   845   C  CD  . GLU A 1 108 ? 25.116  16.771  -15.433 1.00 55.08  ? 108 GLU A CD  1 
ATOM   846   O  OE1 . GLU A 1 108 ? 25.241  15.963  -16.385 1.00 51.40  ? 108 GLU A OE1 1 
ATOM   847   O  OE2 . GLU A 1 108 ? 25.630  17.921  -15.456 1.00 53.55  ? 108 GLU A OE2 1 
ATOM   848   N  N   . LEU A 1 109 ? 20.857  17.284  -12.529 1.00 29.47  ? 109 LEU A N   1 
ATOM   849   C  CA  . LEU A 1 109 ? 19.987  18.444  -12.459 1.00 28.25  ? 109 LEU A CA  1 
ATOM   850   C  C   . LEU A 1 109 ? 20.823  19.712  -12.332 1.00 31.24  ? 109 LEU A C   1 
ATOM   851   O  O   . LEU A 1 109 ? 21.782  19.757  -11.560 1.00 33.10  ? 109 LEU A O   1 
ATOM   852   C  CB  . LEU A 1 109 ? 19.051  18.337  -11.265 1.00 31.08  ? 109 LEU A CB  1 
ATOM   853   C  CG  . LEU A 1 109 ? 18.239  19.594  -11.017 1.00 26.97  ? 109 LEU A CG  1 
ATOM   854   C  CD1 . LEU A 1 109 ? 17.279  19.747  -12.177 1.00 25.86  ? 109 LEU A CD1 1 
ATOM   855   C  CD2 . LEU A 1 109 ? 17.510  19.475  -9.692  1.00 24.65  ? 109 LEU A CD2 1 
ATOM   856   N  N   . ARG A 1 110 ? 20.463  20.742  -13.088 1.00 26.41  ? 110 ARG A N   1 
ATOM   857   C  CA  . ARG A 1 110 ? 21.260  21.962  -13.101 1.00 28.47  ? 110 ARG A CA  1 
ATOM   858   C  C   . ARG A 1 110 ? 20.369  23.151  -12.794 1.00 27.44  ? 110 ARG A C   1 
ATOM   859   O  O   . ARG A 1 110 ? 19.302  23.287  -13.392 1.00 30.55  ? 110 ARG A O   1 
ATOM   860   C  CB  . ARG A 1 110 ? 21.955  22.134  -14.451 1.00 34.97  ? 110 ARG A CB  1 
ATOM   861   C  CG  . ARG A 1 110 ? 22.375  20.820  -15.101 1.00 33.85  ? 110 ARG A CG  1 
ATOM   862   C  CD  . ARG A 1 110 ? 22.985  21.053  -16.460 1.00 40.43  ? 110 ARG A CD  1 
ATOM   863   N  NE  . ARG A 1 110 ? 24.430  21.215  -16.372 1.00 51.84  ? 110 ARG A NE  1 
ATOM   864   C  CZ  . ARG A 1 110 ? 25.304  20.567  -17.131 1.00 57.72  ? 110 ARG A CZ  1 
ATOM   865   N  NH1 . ARG A 1 110 ? 24.910  19.714  -18.064 1.00 53.94  ? 110 ARG A NH1 1 
ATOM   866   N  NH2 . ARG A 1 110 ? 26.605  20.784  -16.952 1.00 58.75  ? 110 ARG A NH2 1 
ATOM   867   N  N   . LEU A 1 111 ? 20.811  24.001  -11.857 1.00 27.81  ? 111 LEU A N   1 
ATOM   868   C  CA  . LEU A 1 111 ? 20.074  25.159  -11.366 1.00 27.17  ? 111 LEU A CA  1 
ATOM   869   C  C   . LEU A 1 111 ? 21.007  26.354  -11.305 1.00 27.21  ? 111 LEU A C   1 
ATOM   870   O  O   . LEU A 1 111 ? 22.134  26.235  -10.822 1.00 27.16  ? 111 LEU A O   1 
ATOM   871   C  CB  . LEU A 1 111 ? 19.506  24.931  -9.973  1.00 25.20  ? 111 LEU A CB  1 
ATOM   872   C  CG  . LEU A 1 111 ? 18.360  23.963  -9.779  1.00 26.23  ? 111 LEU A CG  1 
ATOM   873   C  CD1 . LEU A 1 111 ? 18.022  23.890  -8.265  1.00 25.58  ? 111 LEU A CD1 1 
ATOM   874   C  CD2 . LEU A 1 111 ? 17.195  24.434  -10.588 1.00 22.80  ? 111 LEU A CD2 1 
ATOM   875   N  N   . ARG A 1 112 ? 20.536  27.505  -11.779 1.00 28.71  ? 112 ARG A N   1 
ATOM   876   C  CA  . ARG A 1 112 ? 21.324  28.736  -11.734 1.00 30.08  ? 112 ARG A CA  1 
ATOM   877   C  C   . ARG A 1 112 ? 20.986  29.532  -10.470 1.00 27.28  ? 112 ARG A C   1 
ATOM   878   O  O   . ARG A 1 112 ? 19.834  29.924  -10.266 1.00 28.91  ? 112 ARG A O   1 
ATOM   879   C  CB  . ARG A 1 112 ? 21.078  29.571  -13.001 1.00 25.27  ? 112 ARG A CB  1 
ATOM   880   C  CG  . ARG A 1 112 ? 21.459  28.851  -14.288 1.00 27.27  ? 112 ARG A CG  1 
ATOM   881   C  CD  . ARG A 1 112 ? 21.681  29.812  -15.490 1.00 23.65  ? 112 ARG A CD  1 
ATOM   882   N  NE  . ARG A 1 112 ? 20.645  30.835  -15.554 1.00 25.47  ? 112 ARG A NE  1 
ATOM   883   C  CZ  . ARG A 1 112 ? 19.389  30.609  -15.916 1.00 32.30  ? 112 ARG A CZ  1 
ATOM   884   N  NH1 . ARG A 1 112 ? 18.980  29.402  -16.279 1.00 31.56  ? 112 ARG A NH1 1 
ATOM   885   N  NH2 . ARG A 1 112 ? 18.515  31.614  -15.890 1.00 34.44  ? 112 ARG A NH2 1 
ATOM   886   N  N   . MET A 1 113 ? 21.987  29.766  -9.620  1.00 33.56  ? 113 MET A N   1 
ATOM   887   C  CA  . MET A 1 113 ? 21.851  30.661  -8.472  1.00 36.02  ? 113 MET A CA  1 
ATOM   888   C  C   . MET A 1 113 ? 22.652  31.938  -8.724  1.00 36.36  ? 113 MET A C   1 
ATOM   889   O  O   . MET A 1 113 ? 23.884  31.897  -8.785  1.00 36.82  ? 113 MET A O   1 
ATOM   890   C  CB  . MET A 1 113 ? 22.334  30.021  -7.168  1.00 35.64  ? 113 MET A CB  1 
ATOM   891   C  CG  . MET A 1 113 ? 22.305  28.508  -7.033  1.00 38.44  ? 113 MET A CG  1 
ATOM   892   S  SD  . MET A 1 113 ? 20.699  27.807  -7.354  1.00 42.08  ? 113 MET A SD  1 
ATOM   893   C  CE  . MET A 1 113 ? 20.914  26.152  -6.759  1.00 36.59  ? 113 MET A CE  1 
ATOM   894   N  N   . SER A 1 114 ? 21.960  33.076  -8.822  1.00 38.70  ? 114 SER A N   1 
ATOM   895   C  CA  . SER A 1 114 ? 22.641  34.333  -9.141  1.00 33.98  ? 114 SER A CA  1 
ATOM   896   C  C   . SER A 1 114 ? 23.560  34.812  -8.018  1.00 39.10  ? 114 SER A C   1 
ATOM   897   O  O   . SER A 1 114 ? 24.479  35.592  -8.273  1.00 41.25  ? 114 SER A O   1 
ATOM   898   C  CB  . SER A 1 114 ? 21.618  35.427  -9.452  1.00 31.44  ? 114 SER A CB  1 
ATOM   899   O  OG  . SER A 1 114 ? 20.672  35.016  -10.432 1.00 33.55  ? 114 SER A OG  1 
ATOM   900   N  N   . TYR A 1 115 ? 23.332  34.383  -6.786  1.00 35.99  ? 115 TYR A N   1 
ATOM   901   C  CA  . TYR A 1 115 ? 24.148  34.853  -5.684  1.00 36.12  ? 115 TYR A CA  1 
ATOM   902   C  C   . TYR A 1 115 ? 25.419  34.045  -5.520  1.00 35.92  ? 115 TYR A C   1 
ATOM   903   O  O   . TYR A 1 115 ? 26.227  34.352  -4.635  1.00 35.12  ? 115 TYR A O   1 
ATOM   904   C  CB  . TYR A 1 115 ? 23.334  34.825  -4.396  1.00 39.86  ? 115 TYR A CB  1 
ATOM   905   C  CG  . TYR A 1 115 ? 22.612  33.516  -4.154  1.00 36.73  ? 115 TYR A CG  1 
ATOM   906   C  CD1 . TYR A 1 115 ? 23.235  32.480  -3.476  1.00 38.62  ? 115 TYR A CD1 1 
ATOM   907   C  CD2 . TYR A 1 115 ? 21.309  33.324  -4.587  1.00 32.94  ? 115 TYR A CD2 1 
ATOM   908   C  CE1 . TYR A 1 115 ? 22.580  31.281  -3.224  1.00 37.78  ? 115 TYR A CE1 1 
ATOM   909   C  CE2 . TYR A 1 115 ? 20.654  32.123  -4.353  1.00 38.52  ? 115 TYR A CE2 1 
ATOM   910   C  CZ  . TYR A 1 115 ? 21.300  31.108  -3.669  1.00 34.67  ? 115 TYR A CZ  1 
ATOM   911   O  OH  . TYR A 1 115 ? 20.675  29.907  -3.427  1.00 41.39  ? 115 TYR A OH  1 
ATOM   912   N  N   . ILE A 1 116 ? 25.607  33.025  -6.351  1.00 37.71  ? 116 ILE A N   1 
ATOM   913   C  CA  . ILE A 1 116 ? 26.821  32.218  -6.372  1.00 41.05  ? 116 ILE A CA  1 
ATOM   914   C  C   . ILE A 1 116 ? 27.676  32.659  -7.559  1.00 47.30  ? 116 ILE A C   1 
ATOM   915   O  O   . ILE A 1 116 ? 27.138  32.913  -8.649  1.00 46.84  ? 116 ILE A O   1 
ATOM   916   C  CB  . ILE A 1 116 ? 26.470  30.721  -6.438  1.00 45.71  ? 116 ILE A CB  1 
ATOM   917   C  CG1 . ILE A 1 116 ? 25.478  30.353  -5.321  1.00 40.70  ? 116 ILE A CG1 1 
ATOM   918   C  CG2 . ILE A 1 116 ? 27.724  29.853  -6.454  1.00 43.47  ? 116 ILE A CG2 1 
ATOM   919   C  CD1 . ILE A 1 116 ? 26.099  30.078  -3.975  1.00 36.97  ? 116 ILE A CD1 1 
ATOM   920   N  N   . PRO A 1 117 ? 28.998  32.777  -7.401  1.00 49.78  ? 117 PRO A N   1 
ATOM   921   C  CA  . PRO A 1 117 ? 29.841  33.214  -8.525  1.00 50.15  ? 117 PRO A CA  1 
ATOM   922   C  C   . PRO A 1 117 ? 29.783  32.255  -9.707  1.00 51.79  ? 117 PRO A C   1 
ATOM   923   O  O   . PRO A 1 117 ? 29.551  31.054  -9.552  1.00 54.93  ? 117 PRO A O   1 
ATOM   924   C  CB  . PRO A 1 117 ? 31.249  33.265  -7.920  1.00 57.87  ? 117 PRO A CB  1 
ATOM   925   C  CG  . PRO A 1 117 ? 31.053  33.332  -6.434  1.00 56.42  ? 117 PRO A CG  1 
ATOM   926   C  CD  . PRO A 1 117 ? 29.710  32.768  -6.109  1.00 48.27  ? 117 PRO A CD  1 
ATOM   927   N  N   . GLN A 1 118 ? 30.022  32.806  -10.903 1.00 47.87  ? 118 GLN A N   1 
ATOM   928   C  CA  . GLN A 1 118 ? 29.912  32.043  -12.146 1.00 51.80  ? 118 GLN A CA  1 
ATOM   929   C  C   . GLN A 1 118 ? 30.943  30.919  -12.258 1.00 50.97  ? 118 GLN A C   1 
ATOM   930   O  O   . GLN A 1 118 ? 30.734  29.981  -13.034 1.00 44.97  ? 118 GLN A O   1 
ATOM   931   C  CB  . GLN A 1 118 ? 30.045  32.985  -13.348 1.00 53.31  ? 118 GLN A CB  1 
ATOM   932   C  CG  . GLN A 1 118 ? 28.754  33.693  -13.750 1.00 51.43  ? 118 GLN A CG  1 
ATOM   933   C  CD  . GLN A 1 118 ? 27.978  32.948  -14.828 1.00 55.18  ? 118 GLN A CD  1 
ATOM   934   O  OE1 . GLN A 1 118 ? 28.272  31.791  -15.136 1.00 56.18  ? 118 GLN A OE1 1 
ATOM   935   N  NE2 . GLN A 1 118 ? 26.986  33.615  -15.413 1.00 54.82  ? 118 GLN A NE2 1 
ATOM   936   N  N   . GLU A 1 119 ? 32.051  30.997  -11.514 1.00 57.84  ? 119 GLU A N   1 
ATOM   937   C  CA  . GLU A 1 119 ? 33.098  29.979  -11.548 1.00 56.08  ? 119 GLU A CA  1 
ATOM   938   C  C   . GLU A 1 119 ? 32.693  28.716  -10.812 1.00 59.19  ? 119 GLU A C   1 
ATOM   939   O  O   . GLU A 1 119 ? 33.470  27.756  -10.763 1.00 60.66  ? 119 GLU A O   1 
ATOM   940   C  CB  . GLU A 1 119 ? 34.396  30.531  -10.946 1.00 53.89  ? 119 GLU A CB  1 
ATOM   941   C  CG  . GLU A 1 119 ? 35.238  31.391  -11.895 1.00 59.79  ? 119 GLU A CG  1 
ATOM   942   C  CD  . GLU A 1 119 ? 34.417  32.419  -12.671 1.00 62.45  ? 119 GLU A CD  1 
ATOM   943   O  OE1 . GLU A 1 119 ? 34.015  33.441  -12.063 1.00 62.94  ? 119 GLU A OE1 1 
ATOM   944   O  OE2 . GLU A 1 119 ? 34.170  32.203  -13.884 1.00 58.58  ? 119 GLU A OE2 1 
ATOM   945   N  N   . HIS A 1 120 ? 31.496  28.714  -10.226 1.00 59.81  ? 120 HIS A N   1 
ATOM   946   C  CA  . HIS A 1 120 ? 30.969  27.588  -9.468  1.00 59.78  ? 120 HIS A CA  1 
ATOM   947   C  C   . HIS A 1 120 ? 29.544  27.256  -9.902  1.00 50.93  ? 120 HIS A C   1 
ATOM   948   O  O   . HIS A 1 120 ? 28.820  26.578  -9.169  1.00 49.73  ? 120 HIS A O   1 
ATOM   949   C  CB  . HIS A 1 120 ? 31.014  27.891  -7.966  1.00 59.37  ? 120 HIS A CB  1 
ATOM   950   C  CG  . HIS A 1 120 ? 32.402  28.054  -7.417  1.00 66.53  ? 120 HIS A CG  1 
ATOM   951   N  ND1 . HIS A 1 120 ? 32.726  29.024  -6.492  1.00 63.42  ? 120 HIS A ND1 1 
ATOM   952   C  CD2 . HIS A 1 120 ? 33.546  27.366  -7.653  1.00 67.44  ? 120 HIS A CD2 1 
ATOM   953   C  CE1 . HIS A 1 120 ? 34.007  28.929  -6.183  1.00 65.60  ? 120 HIS A CE1 1 
ATOM   954   N  NE2 . HIS A 1 120 ? 34.528  27.932  -6.874  1.00 66.50  ? 120 HIS A NE2 1 
ATOM   955   N  N   . GLN A 1 121 ? 29.131  27.729  -11.077 1.00 48.00  ? 121 GLN A N   1 
ATOM   956   C  CA  . GLN A 1 121 ? 27.769  27.646  -11.573 1.00 42.91  ? 121 GLN A CA  1 
ATOM   957   C  C   . GLN A 1 121 ? 27.754  26.941  -12.925 1.00 46.38  ? 121 GLN A C   1 
ATOM   958   O  O   . GLN A 1 121 ? 28.743  26.997  -13.664 1.00 44.60  ? 121 GLN A O   1 
ATOM   959   C  CB  . GLN A 1 121 ? 27.139  29.043  -11.713 1.00 43.70  ? 121 GLN A CB  1 
ATOM   960   C  CG  . GLN A 1 121 ? 26.652  29.640  -10.410 1.00 40.68  ? 121 GLN A CG  1 
ATOM   961   C  CD  . GLN A 1 121 ? 25.511  28.838  -9.786  1.00 40.83  ? 121 GLN A CD  1 
ATOM   962   O  OE1 . GLN A 1 121 ? 24.416  28.720  -10.359 1.00 32.71  ? 121 GLN A OE1 1 
ATOM   963   N  NE2 . GLN A 1 121 ? 25.764  28.286  -8.603  1.00 41.94  ? 121 GLN A NE2 1 
ATOM   964   N  N   . PRO A 1 122 ? 26.647  26.261  -13.280 1.00 43.38  ? 122 PRO A N   1 
ATOM   965   C  CA  . PRO A 1 122 ? 25.417  26.153  -12.489 1.00 38.69  ? 122 PRO A CA  1 
ATOM   966   C  C   . PRO A 1 122 ? 25.571  25.194  -11.330 1.00 37.89  ? 122 PRO A C   1 
ATOM   967   O  O   . PRO A 1 122 ? 26.534  24.436  -11.303 1.00 45.75  ? 122 PRO A O   1 
ATOM   968   C  CB  . PRO A 1 122 ? 24.404  25.610  -13.487 1.00 36.19  ? 122 PRO A CB  1 
ATOM   969   C  CG  . PRO A 1 122 ? 25.208  24.762  -14.395 1.00 41.52  ? 122 PRO A CG  1 
ATOM   970   C  CD  . PRO A 1 122 ? 26.596  25.408  -14.479 1.00 41.91  ? 122 PRO A CD  1 
ATOM   971   N  N   . SER A 1 123 ? 24.651  25.239  -10.375 1.00 36.59  ? 123 SER A N   1 
ATOM   972   C  CA  . SER A 1 123 ? 24.634  24.222  -9.333  1.00 38.53  ? 123 SER A CA  1 
ATOM   973   C  C   . SER A 1 123 ? 24.194  22.910  -9.952  1.00 35.17  ? 123 SER A C   1 
ATOM   974   O  O   . SER A 1 123 ? 23.210  22.872  -10.692 1.00 36.66  ? 123 SER A O   1 
ATOM   975   C  CB  . SER A 1 123 ? 23.694  24.621  -8.195  1.00 35.11  ? 123 SER A CB  1 
ATOM   976   O  OG  . SER A 1 123 ? 24.147  25.800  -7.537  1.00 33.73  ? 123 SER A OG  1 
ATOM   977   N  N   . THR A 1 124 ? 24.934  21.839  -9.676  1.00 36.39  ? 124 THR A N   1 
ATOM   978   C  CA  . THR A 1 124 ? 24.685  20.542  -10.286 1.00 33.06  ? 124 THR A CA  1 
ATOM   979   C  C   . THR A 1 124 ? 24.407  19.517  -9.195  1.00 37.18  ? 124 THR A C   1 
ATOM   980   O  O   . THR A 1 124 ? 25.116  19.462  -8.181  1.00 39.84  ? 124 THR A O   1 
ATOM   981   C  CB  . THR A 1 124 ? 25.861  20.122  -11.176 1.00 39.95  ? 124 THR A CB  1 
ATOM   982   O  OG1 . THR A 1 124 ? 25.945  21.029  -12.282 1.00 41.18  ? 124 THR A OG1 1 
ATOM   983   C  CG2 . THR A 1 124 ? 25.679  18.693  -11.715 1.00 37.23  ? 124 THR A CG2 1 
ATOM   984   N  N   . TYR A 1 125 ? 23.344  18.743  -9.387  1.00 35.91  ? 125 TYR A N   1 
ATOM   985   C  CA  . TYR A 1 125 ? 22.895  17.749  -8.421  1.00 36.61  ? 125 TYR A CA  1 
ATOM   986   C  C   . TYR A 1 125 ? 22.865  16.418  -9.145  1.00 32.27  ? 125 TYR A C   1 
ATOM   987   O  O   . TYR A 1 125 ? 22.066  16.225  -10.067 1.00 33.76  ? 125 TYR A O   1 
ATOM   988   C  CB  . TYR A 1 125 ? 21.521  18.096  -7.852  1.00 30.81  ? 125 TYR A CB  1 
ATOM   989   C  CG  . TYR A 1 125 ? 21.435  19.487  -7.304  1.00 27.46  ? 125 TYR A CG  1 
ATOM   990   C  CD1 . TYR A 1 125 ? 21.207  20.567  -8.140  1.00 34.19  ? 125 TYR A CD1 1 
ATOM   991   C  CD2 . TYR A 1 125 ? 21.598  19.729  -5.953  1.00 32.60  ? 125 TYR A CD2 1 
ATOM   992   C  CE1 . TYR A 1 125 ? 21.137  21.853  -7.646  1.00 30.65  ? 125 TYR A CE1 1 
ATOM   993   C  CE2 . TYR A 1 125 ? 21.518  21.014  -5.447  1.00 28.52  ? 125 TYR A CE2 1 
ATOM   994   C  CZ  . TYR A 1 125 ? 21.285  22.063  -6.302  1.00 30.28  ? 125 TYR A CZ  1 
ATOM   995   O  OH  . TYR A 1 125 ? 21.204  23.339  -5.814  1.00 38.73  ? 125 TYR A OH  1 
ATOM   996   N  N   . ARG A 1 126 ? 23.741  15.515  -8.739  1.00 31.53  ? 126 ARG A N   1 
ATOM   997   C  CA  . ARG A 1 126 ? 23.852  14.196  -9.336  1.00 32.26  ? 126 ARG A CA  1 
ATOM   998   C  C   . ARG A 1 126 ? 23.346  13.183  -8.323  1.00 38.98  ? 126 ARG A C   1 
ATOM   999   O  O   . ARG A 1 126 ? 23.837  13.150  -7.192  1.00 43.15  ? 126 ARG A O   1 
ATOM   1000  C  CB  . ARG A 1 126 ? 25.300  13.914  -9.719  1.00 32.95  ? 126 ARG A CB  1 
ATOM   1001  C  CG  . ARG A 1 126 ? 25.736  14.643  -10.955 1.00 38.17  ? 126 ARG A CG  1 
ATOM   1002  C  CD  . ARG A 1 126 ? 26.582  13.742  -11.818 1.00 44.93  ? 126 ARG A CD  1 
ATOM   1003  N  NE  . ARG A 1 126 ? 27.141  14.444  -12.964 1.00 50.20  ? 126 ARG A NE  1 
ATOM   1004  C  CZ  . ARG A 1 126 ? 27.917  15.517  -12.895 1.00 51.13  ? 126 ARG A CZ  1 
ATOM   1005  N  NH1 . ARG A 1 126 ? 28.306  16.022  -11.731 1.00 57.32  ? 126 ARG A NH1 1 
ATOM   1006  N  NH2 . ARG A 1 126 ? 28.321  16.097  -14.022 1.00 51.13  ? 126 ARG A NH2 1 
ATOM   1007  N  N   . VAL A 1 127 ? 22.347  12.384  -8.713  1.00 38.91  ? 127 VAL A N   1 
ATOM   1008  C  CA  . VAL A 1 127 ? 21.862  11.286  -7.879  1.00 37.60  ? 127 VAL A CA  1 
ATOM   1009  C  C   . VAL A 1 127 ? 21.362  10.162  -8.769  1.00 40.32  ? 127 VAL A C   1 
ATOM   1010  O  O   . VAL A 1 127 ? 21.000  10.362  -9.934  1.00 37.14  ? 127 VAL A O   1 
ATOM   1011  C  CB  . VAL A 1 127 ? 20.720  11.671  -6.911  1.00 40.01  ? 127 VAL A CB  1 
ATOM   1012  C  CG1 . VAL A 1 127 ? 21.245  12.444  -5.702  1.00 40.03  ? 127 VAL A CG1 1 
ATOM   1013  C  CG2 . VAL A 1 127 ? 19.623  12.414  -7.654  1.00 39.11  ? 127 VAL A CG2 1 
ATOM   1014  N  N   . THR A 1 128 ? 21.305  8.976   -8.173  1.00 33.67  ? 128 THR A N   1 
ATOM   1015  C  CA  . THR A 1 128 ? 20.869  7.740   -8.788  1.00 36.59  ? 128 THR A CA  1 
ATOM   1016  C  C   . THR A 1 128 ? 19.942  7.064   -7.793  1.00 36.03  ? 128 THR A C   1 
ATOM   1017  O  O   . THR A 1 128 ? 20.121  7.203   -6.581  1.00 40.49  ? 128 THR A O   1 
ATOM   1018  C  CB  . THR A 1 128 ? 22.067  6.831   -9.118  1.00 35.64  ? 128 THR A CB  1 
ATOM   1019  O  OG1 . THR A 1 128 ? 22.902  7.466   -10.089 1.00 34.94  ? 128 THR A OG1 1 
ATOM   1020  C  CG2 . THR A 1 128 ? 21.616  5.480   -9.663  1.00 33.74  ? 128 THR A CG2 1 
ATOM   1021  N  N   . LYS A 1 129 ? 18.938  6.358   -8.302  1.00 34.74  ? 129 LYS A N   1 
ATOM   1022  C  CA  . LYS A 1 129 ? 18.019  5.630   -7.441  1.00 37.50  ? 129 LYS A CA  1 
ATOM   1023  C  C   . LYS A 1 129 ? 17.373  4.507   -8.234  1.00 32.68  ? 129 LYS A C   1 
ATOM   1024  O  O   . LYS A 1 129 ? 16.973  4.708   -9.377  1.00 35.20  ? 129 LYS A O   1 
ATOM   1025  C  CB  . LYS A 1 129 ? 16.954  6.569   -6.866  1.00 33.22  ? 129 LYS A CB  1 
ATOM   1026  C  CG  . LYS A 1 129 ? 15.749  5.901   -6.238  1.00 35.14  ? 129 LYS A CG  1 
ATOM   1027  C  CD  . LYS A 1 129 ? 15.258  6.730   -5.066  1.00 34.41  ? 129 LYS A CD  1 
ATOM   1028  C  CE  . LYS A 1 129 ? 13.745  6.843   -4.989  1.00 33.78  ? 129 LYS A CE  1 
ATOM   1029  N  NZ  . LYS A 1 129 ? 13.044  5.566   -4.817  1.00 37.86  ? 129 LYS A NZ  1 
ATOM   1030  N  N   . HIS A 1 130 ? 17.302  3.323   -7.634  1.00 29.62  ? 130 HIS A N   1 
ATOM   1031  C  CA  . HIS A 1 130 ? 16.461  2.269   -8.171  1.00 30.34  ? 130 HIS A CA  1 
ATOM   1032  C  C   . HIS A 1 130 ? 15.008  2.616   -7.861  1.00 32.29  ? 130 HIS A C   1 
ATOM   1033  O  O   . HIS A 1 130 ? 14.652  2.811   -6.695  1.00 31.82  ? 130 HIS A O   1 
ATOM   1034  C  CB  . HIS A 1 130 ? 16.857  0.916   -7.567  1.00 35.74  ? 130 HIS A CB  1 
ATOM   1035  C  CG  . HIS A 1 130 ? 18.224  0.453   -7.966  1.00 34.12  ? 130 HIS A CG  1 
ATOM   1036  N  ND1 . HIS A 1 130 ? 19.329  0.598   -7.152  1.00 36.37  ? 130 HIS A ND1 1 
ATOM   1037  C  CD2 . HIS A 1 130 ? 18.668  -0.139  -9.101  1.00 33.05  ? 130 HIS A CD2 1 
ATOM   1038  C  CE1 . HIS A 1 130 ? 20.394  0.116   -7.771  1.00 34.71  ? 130 HIS A CE1 1 
ATOM   1039  N  NE2 . HIS A 1 130 ? 20.021  -0.332  -8.957  1.00 35.66  ? 130 HIS A NE2 1 
ATOM   1040  N  N   . VAL A 1 131 ? 14.177  2.733   -8.904  1.00 30.16  ? 131 VAL A N   1 
ATOM   1041  C  CA  . VAL A 1 131 ? 12.781  3.156   -8.784  1.00 26.03  ? 131 VAL A CA  1 
ATOM   1042  C  C   . VAL A 1 131 ? 11.906  2.174   -9.544  1.00 26.07  ? 131 VAL A C   1 
ATOM   1043  O  O   . VAL A 1 131 ? 12.299  1.680   -10.609 1.00 31.20  ? 131 VAL A O   1 
ATOM   1044  C  CB  . VAL A 1 131 ? 12.568  4.572   -9.355  1.00 30.04  ? 131 VAL A CB  1 
ATOM   1045  C  CG1 . VAL A 1 131 ? 12.841  5.652   -8.301  1.00 33.83  ? 131 VAL A CG1 1 
ATOM   1046  C  CG2 . VAL A 1 131 ? 13.457  4.746   -10.553 1.00 22.15  ? 131 VAL A CG2 1 
ATOM   1047  N  N   . THR A 1 132 ? 10.698  1.928   -9.030  1.00 27.18  ? 132 THR A N   1 
ATOM   1048  C  CA  . THR A 1 132 ? 9.796   0.939   -9.602  1.00 26.57  ? 132 THR A CA  1 
ATOM   1049  C  C   . THR A 1 132 ? 8.720   1.629   -10.433 1.00 28.32  ? 132 THR A C   1 
ATOM   1050  O  O   . THR A 1 132 ? 7.882   2.355   -9.891  1.00 27.81  ? 132 THR A O   1 
ATOM   1051  C  CB  . THR A 1 132 ? 9.142   0.080   -8.522  1.00 21.77  ? 132 THR A CB  1 
ATOM   1052  O  OG1 . THR A 1 132 ? 10.153  -0.657  -7.833  1.00 27.31  ? 132 THR A OG1 1 
ATOM   1053  C  CG2 . THR A 1 132 ? 8.194   -0.899  -9.164  1.00 26.63  ? 132 THR A CG2 1 
ATOM   1054  N  N   . LEU A 1 133 ? 8.724   1.349   -11.733 1.00 26.13  ? 133 LEU A N   1 
ATOM   1055  C  CA  . LEU A 1 133 ? 7.732   1.880   -12.657 1.00 23.28  ? 133 LEU A CA  1 
ATOM   1056  C  C   . LEU A 1 133 ? 6.341   1.384   -12.286 1.00 22.88  ? 133 LEU A C   1 
ATOM   1057  O  O   . LEU A 1 133 ? 6.161   0.229   -11.898 1.00 29.14  ? 133 LEU A O   1 
ATOM   1058  C  CB  . LEU A 1 133 ? 8.095   1.432   -14.084 1.00 28.30  ? 133 LEU A CB  1 
ATOM   1059  C  CG  . LEU A 1 133 ? 7.324   1.911   -15.317 1.00 26.31  ? 133 LEU A CG  1 
ATOM   1060  C  CD1 . LEU A 1 133 ? 7.955   3.179   -15.837 1.00 24.23  ? 133 LEU A CD1 1 
ATOM   1061  C  CD2 . LEU A 1 133 ? 7.270   0.824   -16.423 1.00 27.57  ? 133 LEU A CD2 1 
ATOM   1062  N  N   . ALA A 1 134 ? 5.353   2.254   -12.403 1.00 22.27  ? 134 ALA A N   1 
ATOM   1063  C  CA  . ALA A 1 134 ? 3.979   1.843   -12.185 1.00 25.58  ? 134 ALA A CA  1 
ATOM   1064  C  C   . ALA A 1 134 ? 3.673   0.642   -13.082 1.00 32.31  ? 134 ALA A C   1 
ATOM   1065  O  O   . ALA A 1 134 ? 4.048   0.651   -14.265 1.00 28.95  ? 134 ALA A O   1 
ATOM   1066  C  CB  . ALA A 1 134 ? 3.027   3.006   -12.478 1.00 26.87  ? 134 ALA A CB  1 
ATOM   1067  N  N   . PRO A 1 135 ? 3.039   -0.410  -12.559 1.00 31.50  ? 135 PRO A N   1 
ATOM   1068  C  CA  . PRO A 1 135 ? 2.932   -1.666  -13.321 1.00 32.45  ? 135 PRO A CA  1 
ATOM   1069  C  C   . PRO A 1 135 ? 2.110   -1.529  -14.599 1.00 34.42  ? 135 PRO A C   1 
ATOM   1070  O  O   . PRO A 1 135 ? 1.025   -0.928  -14.615 1.00 36.43  ? 135 PRO A O   1 
ATOM   1071  C  CB  . PRO A 1 135 ? 2.271   -2.633  -12.324 1.00 29.81  ? 135 PRO A CB  1 
ATOM   1072  C  CG  . PRO A 1 135 ? 1.763   -1.809  -11.223 1.00 36.36  ? 135 PRO A CG  1 
ATOM   1073  C  CD  . PRO A 1 135 ? 2.639   -0.592  -11.156 1.00 32.42  ? 135 PRO A CD  1 
ATOM   1074  N  N   . GLU A 1 136 ? 2.651   -2.093  -15.683 1.00 33.52  ? 136 GLU A N   1 
ATOM   1075  C  CA  . GLU A 1 136 ? 1.927   -2.223  -16.943 1.00 31.83  ? 136 GLU A CA  1 
ATOM   1076  C  C   . GLU A 1 136 ? 1.165   -3.535  -17.020 1.00 34.92  ? 136 GLU A C   1 
ATOM   1077  O  O   . GLU A 1 136 ? 0.133   -3.593  -17.692 1.00 29.28  ? 136 GLU A O   1 
ATOM   1078  C  CB  . GLU A 1 136 ? 2.882   -2.121  -18.130 1.00 31.76  ? 136 GLU A CB  1 
ATOM   1079  C  CG  . GLU A 1 136 ? 3.601   -0.796  -18.245 1.00 37.22  ? 136 GLU A CG  1 
ATOM   1080  C  CD  . GLU A 1 136 ? 2.735   0.287   -18.857 1.00 39.28  ? 136 GLU A CD  1 
ATOM   1081  O  OE1 . GLU A 1 136 ? 1.530   0.041   -19.068 1.00 41.74  ? 136 GLU A OE1 1 
ATOM   1082  O  OE2 . GLU A 1 136 ? 3.257   1.387   -19.127 1.00 40.42  ? 136 GLU A OE2 1 
ATOM   1083  N  N   . ALA A 1 137 ? 1.642   -4.575  -16.319 1.00 31.08  ? 137 ALA A N   1 
ATOM   1084  C  CA  . ALA A 1 137 ? 0.943   -5.854  -16.272 1.00 25.86  ? 137 ALA A CA  1 
ATOM   1085  C  C   . ALA A 1 137 ? -0.484  -5.672  -15.786 1.00 31.27  ? 137 ALA A C   1 
ATOM   1086  O  O   . ALA A 1 137 ? -0.760  -4.873  -14.884 1.00 32.25  ? 137 ALA A O   1 
ATOM   1087  C  CB  . ALA A 1 137 ? 1.684   -6.836  -15.355 1.00 29.52  ? 137 ALA A CB  1 
ATOM   1088  N  N   . SER A 1 138 ? -1.401  -6.422  -16.388 1.00 31.28  ? 138 SER A N   1 
ATOM   1089  C  CA  . SER A 1 138 ? -2.787  -6.361  -15.945 1.00 30.34  ? 138 SER A CA  1 
ATOM   1090  C  C   . SER A 1 138 ? -2.935  -6.890  -14.524 1.00 29.24  ? 138 SER A C   1 
ATOM   1091  O  O   . SER A 1 138 ? -3.456  -6.200  -13.641 1.00 31.57  ? 138 SER A O   1 
ATOM   1092  C  CB  . SER A 1 138 ? -3.675  -7.157  -16.885 1.00 28.82  ? 138 SER A CB  1 
ATOM   1093  O  OG  . SER A 1 138 ? -4.820  -7.607  -16.179 1.00 34.39  ? 138 SER A OG  1 
ATOM   1094  N  N   . GLY A 1 139 ? -2.520  -8.132  -14.296 1.00 29.06  ? 139 GLY A N   1 
ATOM   1095  C  CA  . GLY A 1 139 ? -2.732  -8.786  -13.019 1.00 25.84  ? 139 GLY A CA  1 
ATOM   1096  C  C   . GLY A 1 139 ? -4.045  -9.518  -12.864 1.00 29.14  ? 139 GLY A C   1 
ATOM   1097  O  O   . GLY A 1 139 ? -4.318  -10.024 -11.769 1.00 27.52  ? 139 GLY A O   1 
ATOM   1098  N  N   . ALA A 1 140 ? -4.868  -9.609  -13.918 1.00 27.44  ? 140 ALA A N   1 
ATOM   1099  C  CA  . ALA A 1 140 ? -6.106  -10.381 -13.806 1.00 27.21  ? 140 ALA A CA  1 
ATOM   1100  C  C   . ALA A 1 140 ? -5.779  -11.809 -13.356 1.00 30.97  ? 140 ALA A C   1 
ATOM   1101  O  O   . ALA A 1 140 ? -4.688  -12.315 -13.644 1.00 30.58  ? 140 ALA A O   1 
ATOM   1102  C  CB  . ALA A 1 140 ? -6.867  -10.395 -15.135 1.00 28.42  ? 140 ALA A CB  1 
ATOM   1103  N  N   . PRO A 1 141 ? -6.674  -12.485 -12.631 1.00 26.92  ? 141 PRO A N   1 
ATOM   1104  C  CA  . PRO A 1 141 ? -8.003  -12.052 -12.204 1.00 28.68  ? 141 PRO A CA  1 
ATOM   1105  C  C   . PRO A 1 141 ? -8.050  -11.455 -10.800 1.00 28.07  ? 141 PRO A C   1 
ATOM   1106  O  O   . PRO A 1 141 ? -9.139  -11.292 -10.265 1.00 30.09  ? 141 PRO A O   1 
ATOM   1107  C  CB  . PRO A 1 141 ? -8.791  -13.356 -12.228 1.00 29.97  ? 141 PRO A CB  1 
ATOM   1108  C  CG  . PRO A 1 141 ? -7.793  -14.356 -11.776 1.00 29.16  ? 141 PRO A CG  1 
ATOM   1109  C  CD  . PRO A 1 141 ? -6.432  -13.888 -12.269 1.00 28.22  ? 141 PRO A CD  1 
ATOM   1110  N  N   . PHE A 1 142 ? -6.901  -11.185 -10.194 1.00 29.26  ? 142 PHE A N   1 
ATOM   1111  C  CA  . PHE A 1 142 ? -6.888  -10.620 -8.844  1.00 30.85  ? 142 PHE A CA  1 
ATOM   1112  C  C   . PHE A 1 142 ? -7.187  -9.121  -8.875  1.00 31.17  ? 142 PHE A C   1 
ATOM   1113  O  O   . PHE A 1 142 ? -6.997  -8.441  -9.892  1.00 28.90  ? 142 PHE A O   1 
ATOM   1114  C  CB  . PHE A 1 142 ? -5.537  -10.872 -8.181  1.00 25.20  ? 142 PHE A CB  1 
ATOM   1115  C  CG  . PHE A 1 142 ? -5.119  -12.308 -8.238  1.00 30.08  ? 142 PHE A CG  1 
ATOM   1116  C  CD1 . PHE A 1 142 ? -5.868  -13.283 -7.588  1.00 28.25  ? 142 PHE A CD1 1 
ATOM   1117  C  CD2 . PHE A 1 142 ? -4.015  -12.689 -8.974  1.00 27.74  ? 142 PHE A CD2 1 
ATOM   1118  C  CE1 . PHE A 1 142 ? -5.497  -14.631 -7.647  1.00 31.36  ? 142 PHE A CE1 1 
ATOM   1119  C  CE2 . PHE A 1 142 ? -3.643  -14.022 -9.046  1.00 33.97  ? 142 PHE A CE2 1 
ATOM   1120  C  CZ  . PHE A 1 142 ? -4.384  -14.997 -8.375  1.00 31.76  ? 142 PHE A CZ  1 
ATOM   1121  N  N   . ARG A 1 143 ? -7.649  -8.610  -7.733  1.00 32.94  ? 143 ARG A N   1 
ATOM   1122  C  CA  . ARG A 1 143 ? -7.862  -7.184  -7.510  1.00 30.20  ? 143 ARG A CA  1 
ATOM   1123  C  C   . ARG A 1 143 ? -6.765  -6.625  -6.604  1.00 30.36  ? 143 ARG A C   1 
ATOM   1124  O  O   . ARG A 1 143 ? -6.347  -7.276  -5.639  1.00 30.88  ? 143 ARG A O   1 
ATOM   1125  C  CB  . ARG A 1 143 ? -9.245  -6.937  -6.896  1.00 28.47  ? 143 ARG A CB  1 
ATOM   1126  C  CG  . ARG A 1 143 ? -10.390 -7.475  -7.738  1.00 32.08  ? 143 ARG A CG  1 
ATOM   1127  C  CD  . ARG A 1 143 ? -11.703 -6.790  -7.445  1.00 33.83  ? 143 ARG A CD  1 
ATOM   1128  N  NE  . ARG A 1 143 ? -11.618 -5.373  -7.776  1.00 35.92  ? 143 ARG A NE  1 
ATOM   1129  C  CZ  . ARG A 1 143 ? -12.438 -4.439  -7.309  1.00 35.71  ? 143 ARG A CZ  1 
ATOM   1130  N  NH1 . ARG A 1 143 ? -13.485 -4.750  -6.557  1.00 38.48  ? 143 ARG A NH1 1 
ATOM   1131  N  NH2 . ARG A 1 143 ? -12.188 -3.159  -7.587  1.00 34.35  ? 143 ARG A NH2 1 
ATOM   1132  N  N   . TYR A 1 144 ? -6.293  -5.420  -6.899  1.00 25.12  ? 144 TYR A N   1 
ATOM   1133  C  CA  . TYR A 1 144 ? -5.044  -4.948  -6.321  1.00 24.37  ? 144 TYR A CA  1 
ATOM   1134  C  C   . TYR A 1 144 ? -5.258  -3.803  -5.335  1.00 26.45  ? 144 TYR A C   1 
ATOM   1135  O  O   . TYR A 1 144 ? -5.856  -2.776  -5.677  1.00 28.16  ? 144 TYR A O   1 
ATOM   1136  C  CB  . TYR A 1 144 ? -4.080  -4.568  -7.429  1.00 24.39  ? 144 TYR A CB  1 
ATOM   1137  C  CG  . TYR A 1 144 ? -3.635  -5.830  -8.108  1.00 31.05  ? 144 TYR A CG  1 
ATOM   1138  C  CD1 . TYR A 1 144 ? -2.688  -6.656  -7.512  1.00 33.52  ? 144 TYR A CD1 1 
ATOM   1139  C  CD2 . TYR A 1 144 ? -4.224  -6.251  -9.294  1.00 30.09  ? 144 TYR A CD2 1 
ATOM   1140  C  CE1 . TYR A 1 144 ? -2.300  -7.842  -8.102  1.00 32.02  ? 144 TYR A CE1 1 
ATOM   1141  C  CE2 . TYR A 1 144 ? -3.844  -7.457  -9.896  1.00 31.36  ? 144 TYR A CE2 1 
ATOM   1142  C  CZ  . TYR A 1 144 ? -2.884  -8.240  -9.294  1.00 32.75  ? 144 TYR A CZ  1 
ATOM   1143  O  OH  . TYR A 1 144 ? -2.502  -9.422  -9.873  1.00 31.14  ? 144 TYR A OH  1 
ATOM   1144  N  N   . GLY A 1 145 ? -4.736  -3.987  -4.112  1.00 25.71  ? 145 GLY A N   1 
ATOM   1145  C  CA  . GLY A 1 145 ? -4.906  -3.026  -3.041  1.00 22.69  ? 145 GLY A CA  1 
ATOM   1146  C  C   . GLY A 1 145 ? -3.652  -2.869  -2.196  1.00 28.27  ? 145 GLY A C   1 
ATOM   1147  O  O   . GLY A 1 145 ? -2.656  -3.581  -2.365  1.00 24.21  ? 145 GLY A O   1 
ATOM   1148  N  N   . VAL A 1 146 ? -3.730  -1.920  -1.263  1.00 29.44  ? 146 VAL A N   1 
ATOM   1149  C  CA  . VAL A 1 146 ? -2.641  -1.633  -0.341  1.00 21.89  ? 146 VAL A CA  1 
ATOM   1150  C  C   . VAL A 1 146 ? -3.257  -1.361  1.013   1.00 25.34  ? 146 VAL A C   1 
ATOM   1151  O  O   . VAL A 1 146 ? -4.186  -0.549  1.118   1.00 23.26  ? 146 VAL A O   1 
ATOM   1152  C  CB  . VAL A 1 146 ? -1.816  -0.407  -0.776  1.00 23.85  ? 146 VAL A CB  1 
ATOM   1153  C  CG1 . VAL A 1 146 ? -0.774  -0.053  0.291   1.00 23.42  ? 146 VAL A CG1 1 
ATOM   1154  C  CG2 . VAL A 1 146 ? -1.159  -0.631  -2.117  1.00 24.56  ? 146 VAL A CG2 1 
ATOM   1155  N  N   . SER A 1 147 ? -2.723  -1.995  2.052   1.00 22.79  ? 147 SER A N   1 
ATOM   1156  C  CA  . SER A 1 147 ? -3.043  -1.593  3.408   1.00 22.62  ? 147 SER A CA  1 
ATOM   1157  C  C   . SER A 1 147 ? -2.102  -0.488  3.869   1.00 18.30  ? 147 SER A C   1 
ATOM   1158  O  O   . SER A 1 147 ? -0.888  -0.609  3.743   1.00 23.28  ? 147 SER A O   1 
ATOM   1159  C  CB  . SER A 1 147 ? -2.939  -2.774  4.373   1.00 23.14  ? 147 SER A CB  1 
ATOM   1160  O  OG  . SER A 1 147 ? -3.036  -2.262  5.691   1.00 22.79  ? 147 SER A OG  1 
ATOM   1161  N  N   . LEU A 1 148 ? -2.662  0.542   4.477   1.00 22.82  ? 148 LEU A N   1 
ATOM   1162  C  CA  . LEU A 1 148 ? -1.851  1.553   5.145   1.00 20.32  ? 148 LEU A CA  1 
ATOM   1163  C  C   . LEU A 1 148 ? -0.920  0.957   6.203   1.00 24.96  ? 148 LEU A C   1 
ATOM   1164  O  O   . LEU A 1 148 ? 0.024   1.628   6.639   1.00 25.78  ? 148 LEU A O   1 
ATOM   1165  C  CB  . LEU A 1 148 ? -2.783  2.575   5.785   1.00 24.00  ? 148 LEU A CB  1 
ATOM   1166  C  CG  . LEU A 1 148 ? -3.460  3.592   4.887   1.00 22.92  ? 148 LEU A CG  1 
ATOM   1167  C  CD1 . LEU A 1 148 ? -3.982  4.667   5.786   1.00 26.68  ? 148 LEU A CD1 1 
ATOM   1168  C  CD2 . LEU A 1 148 ? -2.515  4.171   3.825   1.00 21.09  ? 148 LEU A CD2 1 
ATOM   1169  N  N   . TYR A 1 149 ? -1.190  -0.272  6.661   1.00 27.43  ? 149 TYR A N   1 
ATOM   1170  C  CA  . TYR A 1 149 ? -0.246  -0.966  7.531   1.00 22.64  ? 149 TYR A CA  1 
ATOM   1171  C  C   . TYR A 1 149 ? 1.128   -1.035  6.895   1.00 24.10  ? 149 TYR A C   1 
ATOM   1172  O  O   . TYR A 1 149 ? 2.147   -0.939  7.588   1.00 20.87  ? 149 TYR A O   1 
ATOM   1173  C  CB  . TYR A 1 149 ? -0.731  -2.391  7.867   1.00 19.48  ? 149 TYR A CB  1 
ATOM   1174  C  CG  . TYR A 1 149 ? 0.347   -3.145  8.581   1.00 23.76  ? 149 TYR A CG  1 
ATOM   1175  C  CD1 . TYR A 1 149 ? 0.663   -2.829  9.895   1.00 32.50  ? 149 TYR A CD1 1 
ATOM   1176  C  CD2 . TYR A 1 149 ? 1.073   -4.150  7.958   1.00 27.01  ? 149 TYR A CD2 1 
ATOM   1177  C  CE1 . TYR A 1 149 ? 1.663   -3.483  10.566  1.00 35.43  ? 149 TYR A CE1 1 
ATOM   1178  C  CE2 . TYR A 1 149 ? 2.086   -4.815  8.628   1.00 25.90  ? 149 TYR A CE2 1 
ATOM   1179  C  CZ  . TYR A 1 149 ? 2.370   -4.471  9.933   1.00 34.91  ? 149 TYR A CZ  1 
ATOM   1180  O  OH  . TYR A 1 149 ? 3.356   -5.100  10.643  1.00 45.21  ? 149 TYR A OH  1 
ATOM   1181  N  N   . SER A 1 150 ? 1.173   -1.228  5.573   1.00 21.00  ? 150 SER A N   1 
ATOM   1182  C  CA  . SER A 1 150 ? 2.426   -1.256  4.832   1.00 23.02  ? 150 SER A CA  1 
ATOM   1183  C  C   . SER A 1 150 ? 3.326   -0.050  5.108   1.00 22.48  ? 150 SER A C   1 
ATOM   1184  O  O   . SER A 1 150 ? 4.539   -0.147  4.898   1.00 23.59  ? 150 SER A O   1 
ATOM   1185  C  CB  . SER A 1 150 ? 2.129   -1.317  3.322   1.00 26.54  ? 150 SER A CB  1 
ATOM   1186  O  OG  . SER A 1 150 ? 1.768   -2.634  2.888   1.00 27.28  ? 150 SER A OG  1 
ATOM   1187  N  N   . TYR A 1 151 ? 2.766   1.080   5.557   1.00 24.33  ? 151 TYR A N   1 
ATOM   1188  C  CA  . TYR A 1 151 ? 3.507   2.320   5.786   1.00 25.62  ? 151 TYR A CA  1 
ATOM   1189  C  C   . TYR A 1 151 ? 3.655   2.647   7.272   1.00 26.21  ? 151 TYR A C   1 
ATOM   1190  O  O   . TYR A 1 151 ? 3.864   3.812   7.625   1.00 20.85  ? 151 TYR A O   1 
ATOM   1191  C  CB  . TYR A 1 151 ? 2.829   3.499   5.081   1.00 22.89  ? 151 TYR A CB  1 
ATOM   1192  C  CG  . TYR A 1 151 ? 2.688   3.367   3.584   1.00 27.66  ? 151 TYR A CG  1 
ATOM   1193  C  CD1 . TYR A 1 151 ? 3.706   2.808   2.811   1.00 27.05  ? 151 TYR A CD1 1 
ATOM   1194  C  CD2 . TYR A 1 151 ? 1.544   3.819   2.934   1.00 23.29  ? 151 TYR A CD2 1 
ATOM   1195  C  CE1 . TYR A 1 151 ? 3.584   2.692   1.443   1.00 27.25  ? 151 TYR A CE1 1 
ATOM   1196  C  CE2 . TYR A 1 151 ? 1.412   3.700   1.550   1.00 25.80  ? 151 TYR A CE2 1 
ATOM   1197  C  CZ  . TYR A 1 151 ? 2.432   3.136   0.815   1.00 30.34  ? 151 TYR A CZ  1 
ATOM   1198  O  OH  . TYR A 1 151 ? 2.312   3.011   -0.551  1.00 28.42  ? 151 TYR A OH  1 
ATOM   1199  N  N   . MET A 1 152 ? 3.490   1.655   8.149   1.00 24.07  ? 152 MET A N   1 
ATOM   1200  C  CA  . MET A 1 152 ? 3.740   1.838   9.570   1.00 21.44  ? 152 MET A CA  1 
ATOM   1201  C  C   . MET A 1 152 ? 5.102   2.476   9.803   1.00 22.13  ? 152 MET A C   1 
ATOM   1202  O  O   . MET A 1 152 ? 6.078   2.137   9.134   1.00 20.77  ? 152 MET A O   1 
ATOM   1203  C  CB  . MET A 1 152 ? 3.695   0.499   10.299  1.00 25.79  ? 152 MET A CB  1 
ATOM   1204  C  CG  . MET A 1 152 ? 4.204   0.559   11.738  1.00 29.22  ? 152 MET A CG  1 
ATOM   1205  S  SD  . MET A 1 152 ? 4.625   -1.068  12.372  1.00 34.64  ? 152 MET A SD  1 
ATOM   1206  C  CE  . MET A 1 152 ? 5.273   -0.605  13.984  1.00 28.93  ? 152 MET A CE  1 
ATOM   1207  N  N   . SER A 1 153 ? 5.148   3.371   10.801  1.00 22.28  ? 153 SER A N   1 
ATOM   1208  C  CA  . SER A 1 153 ? 6.265   4.234   11.187  1.00 24.47  ? 153 SER A CA  1 
ATOM   1209  C  C   . SER A 1 153 ? 6.417   5.396   10.197  1.00 21.69  ? 153 SER A C   1 
ATOM   1210  O  O   . SER A 1 153 ? 6.531   6.550   10.623  1.00 24.65  ? 153 SER A O   1 
ATOM   1211  C  CB  . SER A 1 153 ? 7.568   3.443   11.355  1.00 22.64  ? 153 SER A CB  1 
ATOM   1212  O  OG  . SER A 1 153 ? 7.387   2.382   12.290  1.00 29.38  ? 153 SER A OG  1 
ATOM   1213  N  N   . ASP A 1 154 ? 6.385   5.124   8.890   1.00 23.58  ? 154 ASP A N   1 
ATOM   1214  C  CA  . ASP A 1 154 ? 6.316   6.208   7.910   1.00 24.65  ? 154 ASP A CA  1 
ATOM   1215  C  C   . ASP A 1 154 ? 5.088   7.070   8.143   1.00 26.28  ? 154 ASP A C   1 
ATOM   1216  O  O   . ASP A 1 154 ? 5.183   8.302   8.208   1.00 25.67  ? 154 ASP A O   1 
ATOM   1217  C  CB  . ASP A 1 154 ? 6.306   5.649   6.480   1.00 23.94  ? 154 ASP A CB  1 
ATOM   1218  C  CG  . ASP A 1 154 ? 7.676   5.198   6.040   1.00 30.44  ? 154 ASP A CG  1 
ATOM   1219  O  OD1 . ASP A 1 154 ? 8.641   5.762   6.606   1.00 27.60  ? 154 ASP A OD1 1 
ATOM   1220  O  OD2 . ASP A 1 154 ? 7.801   4.305   5.144   1.00 29.33  ? 154 ASP A OD2 1 
ATOM   1221  N  N   . TYR A 1 155 ? 3.927   6.433   8.290   1.00 23.87  ? 155 TYR A N   1 
ATOM   1222  C  CA  . TYR A 1 155 ? 2.676   7.148   8.480   1.00 25.55  ? 155 TYR A CA  1 
ATOM   1223  C  C   . TYR A 1 155 ? 2.717   7.959   9.764   1.00 20.33  ? 155 TYR A C   1 
ATOM   1224  O  O   . TYR A 1 155 ? 2.923   7.411   10.848  1.00 20.11  ? 155 TYR A O   1 
ATOM   1225  C  CB  . TYR A 1 155 ? 1.500   6.164   8.526   1.00 21.77  ? 155 TYR A CB  1 
ATOM   1226  C  CG  . TYR A 1 155 ? 0.181   6.831   8.252   1.00 22.45  ? 155 TYR A CG  1 
ATOM   1227  C  CD1 . TYR A 1 155 ? -0.232  7.061   6.952   1.00 25.15  ? 155 TYR A CD1 1 
ATOM   1228  C  CD2 . TYR A 1 155 ? -0.637  7.268   9.283   1.00 22.00  ? 155 TYR A CD2 1 
ATOM   1229  C  CE1 . TYR A 1 155 ? -1.443  7.686   6.677   1.00 26.77  ? 155 TYR A CE1 1 
ATOM   1230  C  CE2 . TYR A 1 155 ? -1.853  7.905   9.010   1.00 23.38  ? 155 TYR A CE2 1 
ATOM   1231  C  CZ  . TYR A 1 155 ? -2.238  8.101   7.700   1.00 22.93  ? 155 TYR A CZ  1 
ATOM   1232  O  OH  . TYR A 1 155 ? -3.432  8.721   7.375   1.00 28.23  ? 155 TYR A OH  1 
ATOM   1233  N  N   . GLY A 1 156 ? 2.489   9.255   9.648   1.00 22.63  ? 156 GLY A N   1 
ATOM   1234  C  CA  . GLY A 1 156 ? 2.578   10.145  10.790  1.00 22.46  ? 156 GLY A CA  1 
ATOM   1235  C  C   . GLY A 1 156 ? 3.949   10.736  11.080  1.00 22.60  ? 156 GLY A C   1 
ATOM   1236  O  O   . GLY A 1 156 ? 4.047   11.603  11.956  1.00 29.06  ? 156 GLY A O   1 
ATOM   1237  N  N   . THR A 1 157 ? 5.015   10.283  10.416  1.00 21.92  ? 157 THR A N   1 
ATOM   1238  C  CA  . THR A 1 157 ? 6.323   10.923  10.538  1.00 21.04  ? 157 THR A CA  1 
ATOM   1239  C  C   . THR A 1 157 ? 6.791   11.532  9.225   1.00 25.43  ? 157 THR A C   1 
ATOM   1240  O  O   . THR A 1 157 ? 7.284   12.657  9.213   1.00 23.04  ? 157 THR A O   1 
ATOM   1241  C  CB  . THR A 1 157 ? 7.406   9.967   11.039  1.00 21.09  ? 157 THR A CB  1 
ATOM   1242  O  OG1 . THR A 1 157 ? 7.621   8.924   10.080  1.00 23.14  ? 157 THR A OG1 1 
ATOM   1243  C  CG2 . THR A 1 157 ? 7.054   9.377   12.412  1.00 19.22  ? 157 THR A CG2 1 
ATOM   1244  N  N   . VAL A 1 158 ? 6.669   10.791  8.128   1.00 22.17  ? 158 VAL A N   1 
ATOM   1245  C  CA  . VAL A 1 158 ? 6.963   11.291  6.791   1.00 24.32  ? 158 VAL A CA  1 
ATOM   1246  C  C   . VAL A 1 158 ? 5.762   11.212  5.858   1.00 26.27  ? 158 VAL A C   1 
ATOM   1247  O  O   . VAL A 1 158 ? 5.838   11.713  4.727   1.00 23.38  ? 158 VAL A O   1 
ATOM   1248  C  CB  . VAL A 1 158 ? 8.156   10.533  6.170   1.00 21.47  ? 158 VAL A CB  1 
ATOM   1249  C  CG1 . VAL A 1 158 ? 9.334   10.491  7.160   1.00 21.36  ? 158 VAL A CG1 1 
ATOM   1250  C  CG2 . VAL A 1 158 ? 7.731   9.113   5.779   1.00 23.77  ? 158 VAL A CG2 1 
ATOM   1251  N  N   . MET A 1 159 ? 4.655   10.617  6.283   1.00 20.07  ? 159 MET A N   1 
ATOM   1252  C  CA  . MET A 1 159 ? 3.545   10.327  5.389   1.00 25.67  ? 159 MET A CA  1 
ATOM   1253  C  C   . MET A 1 159 ? 2.246   10.784  6.030   1.00 23.44  ? 159 MET A C   1 
ATOM   1254  O  O   . MET A 1 159 ? 2.058   10.600  7.232   1.00 26.33  ? 159 MET A O   1 
ATOM   1255  C  CB  . MET A 1 159 ? 3.501   8.801   5.118   1.00 30.41  ? 159 MET A CB  1 
ATOM   1256  C  CG  . MET A 1 159 ? 2.409   8.349   4.183   1.00 28.67  ? 159 MET A CG  1 
ATOM   1257  S  SD  . MET A 1 159 ? 2.929   6.917   3.246   1.00 35.58  ? 159 MET A SD  1 
ATOM   1258  C  CE  . MET A 1 159 ? 4.548   7.434   2.676   1.00 33.79  ? 159 MET A CE  1 
ATOM   1259  N  N   . ASP A 1 160 ? 1.361   11.410  5.258   1.00 22.47  ? 160 ASP A N   1 
ATOM   1260  C  CA  . ASP A 1 160 ? 0.001   11.643  5.730   1.00 20.83  ? 160 ASP A CA  1 
ATOM   1261  C  C   . ASP A 1 160 ? -0.970  10.900  4.812   1.00 23.64  ? 160 ASP A C   1 
ATOM   1262  O  O   . ASP A 1 160 ? -0.555  10.223  3.876   1.00 20.79  ? 160 ASP A O   1 
ATOM   1263  C  CB  . ASP A 1 160 ? -0.331  13.132  5.826   1.00 20.99  ? 160 ASP A CB  1 
ATOM   1264  C  CG  . ASP A 1 160 ? -0.175  13.864  4.510   1.00 23.59  ? 160 ASP A CG  1 
ATOM   1265  O  OD1 . ASP A 1 160 ? 0.195   13.240  3.513   1.00 26.61  ? 160 ASP A OD1 1 
ATOM   1266  O  OD2 . ASP A 1 160 ? -0.434  15.080  4.480   1.00 26.10  ? 160 ASP A OD2 1 
ATOM   1267  N  N   . LEU A 1 161 ? -2.268  10.988  5.121   1.00 21.05  ? 161 LEU A N   1 
ATOM   1268  C  CA  . LEU A 1 161 ? -3.253  10.195  4.395   1.00 21.20  ? 161 LEU A CA  1 
ATOM   1269  C  C   . LEU A 1 161 ? -3.205  10.482  2.900   1.00 27.55  ? 161 LEU A C   1 
ATOM   1270  O  O   . LEU A 1 161 ? -3.209  9.555   2.074   1.00 24.29  ? 161 LEU A O   1 
ATOM   1271  C  CB  . LEU A 1 161 ? -4.660  10.462  4.930   1.00 23.41  ? 161 LEU A CB  1 
ATOM   1272  C  CG  . LEU A 1 161 ? -5.823  9.749   4.217   1.00 22.69  ? 161 LEU A CG  1 
ATOM   1273  C  CD1 . LEU A 1 161 ? -5.688  8.240   4.316   1.00 26.95  ? 161 LEU A CD1 1 
ATOM   1274  C  CD2 . LEU A 1 161 ? -7.156  10.182  4.768   1.00 21.87  ? 161 LEU A CD2 1 
ATOM   1275  N  N   . GLU A 1 162 ? -3.174  11.765  2.522   1.00 24.96  ? 162 GLU A N   1 
ATOM   1276  C  CA  . GLU A 1 162 ? -3.235  12.065  1.097   1.00 22.80  ? 162 GLU A CA  1 
ATOM   1277  C  C   . GLU A 1 162 ? -1.997  11.564  0.376   1.00 25.19  ? 162 GLU A C   1 
ATOM   1278  O  O   . GLU A 1 162 ? -2.081  11.113  -0.770  1.00 26.38  ? 162 GLU A O   1 
ATOM   1279  C  CB  . GLU A 1 162 ? -3.421  13.556  0.839   1.00 27.04  ? 162 GLU A CB  1 
ATOM   1280  C  CG  . GLU A 1 162 ? -3.400  13.840  -0.681  1.00 30.73  ? 162 GLU A CG  1 
ATOM   1281  C  CD  . GLU A 1 162 ? -4.006  15.159  -1.063  1.00 31.62  ? 162 GLU A CD  1 
ATOM   1282  O  OE1 . GLU A 1 162 ? -4.152  16.035  -0.170  1.00 32.71  ? 162 GLU A OE1 1 
ATOM   1283  O  OE2 . GLU A 1 162 ? -4.337  15.300  -2.269  1.00 26.73  ? 162 GLU A OE2 1 
ATOM   1284  N  N   . THR A 1 163 ? -0.833  11.629  1.031   1.00 27.33  ? 163 THR A N   1 
ATOM   1285  C  CA  . THR A 1 163 ? 0.383   11.131  0.402   1.00 24.81  ? 163 THR A CA  1 
ATOM   1286  C  C   . THR A 1 163 ? 0.312   9.625   0.168   1.00 21.87  ? 163 THR A C   1 
ATOM   1287  O  O   . THR A 1 163 ? 0.786   9.126   -0.857  1.00 20.14  ? 163 THR A O   1 
ATOM   1288  C  CB  . THR A 1 163 ? 1.594   11.487  1.262   1.00 23.29  ? 163 THR A CB  1 
ATOM   1289  O  OG1 . THR A 1 163 ? 1.610   12.900  1.480   1.00 26.37  ? 163 THR A OG1 1 
ATOM   1290  C  CG2 . THR A 1 163 ? 2.875   11.069  0.579   1.00 26.40  ? 163 THR A CG2 1 
ATOM   1291  N  N   . ALA A 1 164 ? -0.238  8.868   1.125   1.00 25.49  ? 164 ALA A N   1 
ATOM   1292  C  CA  . ALA A 1 164 ? -0.294  7.426   0.926   1.00 23.24  ? 164 ALA A CA  1 
ATOM   1293  C  C   . ALA A 1 164 ? -1.292  7.050   -0.177  1.00 22.13  ? 164 ALA A C   1 
ATOM   1294  O  O   . ALA A 1 164 ? -1.024  6.161   -1.001  1.00 24.13  ? 164 ALA A O   1 
ATOM   1295  C  CB  . ALA A 1 164 ? -0.636  6.740   2.255   1.00 22.71  ? 164 ALA A CB  1 
ATOM   1296  N  N   . MET A 1 165 ? -2.458  7.686   -0.201  1.00 24.17  ? 165 MET A N   1 
ATOM   1297  C  CA  . MET A 1 165 ? -3.415  7.382   -1.262  1.00 24.17  ? 165 MET A CA  1 
ATOM   1298  C  C   . MET A 1 165 ? -2.839  7.702   -2.642  1.00 29.41  ? 165 MET A C   1 
ATOM   1299  O  O   . MET A 1 165 ? -2.993  6.917   -3.594  1.00 26.41  ? 165 MET A O   1 
ATOM   1300  C  CB  . MET A 1 165 ? -4.709  8.148   -1.025  1.00 24.91  ? 165 MET A CB  1 
ATOM   1301  C  CG  . MET A 1 165 ? -5.541  7.615   0.120   1.00 28.37  ? 165 MET A CG  1 
ATOM   1302  S  SD  . MET A 1 165 ? -7.027  8.598   0.362   1.00 40.41  ? 165 MET A SD  1 
ATOM   1303  C  CE  . MET A 1 165 ? -8.185  7.636   -0.529  1.00 27.69  ? 165 MET A CE  1 
ATOM   1304  N  N   . ALA A 1 166 ? -2.182  8.857   -2.774  1.00 23.21  ? 166 ALA A N   1 
ATOM   1305  C  CA  . ALA A 1 166 ? -1.487  9.185   -4.016  1.00 22.94  ? 166 ALA A CA  1 
ATOM   1306  C  C   . ALA A 1 166 ? -0.482  8.113   -4.384  1.00 24.11  ? 166 ALA A C   1 
ATOM   1307  O  O   . ALA A 1 166 ? -0.347  7.769   -5.559  1.00 18.42  ? 166 ALA A O   1 
ATOM   1308  C  CB  . ALA A 1 166 ? -0.779  10.522  -3.883  1.00 27.47  ? 166 ALA A CB  1 
ATOM   1309  N  N   . SER A 1 167 ? 0.226   7.556   -3.387  1.00 24.77  ? 167 SER A N   1 
ATOM   1310  C  CA  . SER A 1 167 ? 1.147   6.460   -3.675  1.00 22.27  ? 167 SER A CA  1 
ATOM   1311  C  C   . SER A 1 167 ? 0.396   5.207   -4.116  1.00 25.06  ? 167 SER A C   1 
ATOM   1312  O  O   . SER A 1 167 ? 0.873   4.476   -4.993  1.00 27.63  ? 167 SER A O   1 
ATOM   1313  C  CB  . SER A 1 167 ? 2.017   6.157   -2.459  1.00 22.09  ? 167 SER A CB  1 
ATOM   1314  O  OG  . SER A 1 167 ? 1.294   5.369   -1.536  1.00 21.30  ? 167 SER A OG  1 
ATOM   1315  N  N   . ILE A 1 168 ? -0.772  4.938   -3.521  1.00 23.47  ? 168 ILE A N   1 
ATOM   1316  C  CA  . ILE A 1 168 ? -1.544  3.745   -3.884  1.00 23.41  ? 168 ILE A CA  1 
ATOM   1317  C  C   . ILE A 1 168 ? -2.157  3.905   -5.275  1.00 30.68  ? 168 ILE A C   1 
ATOM   1318  O  O   . ILE A 1 168 ? -2.036  3.017   -6.133  1.00 28.78  ? 168 ILE A O   1 
ATOM   1319  C  CB  . ILE A 1 168 ? -2.615  3.457   -2.816  1.00 28.87  ? 168 ILE A CB  1 
ATOM   1320  C  CG1 . ILE A 1 168 ? -1.938  3.058   -1.508  1.00 23.57  ? 168 ILE A CG1 1 
ATOM   1321  C  CG2 . ILE A 1 168 ? -3.580  2.346   -3.257  1.00 26.18  ? 168 ILE A CG2 1 
ATOM   1322  C  CD1 . ILE A 1 168 ? -2.617  3.604   -0.286  1.00 26.25  ? 168 ILE A CD1 1 
ATOM   1323  N  N   . ALA A 1 169 ? -2.799  5.053   -5.525  1.00 23.08  ? 169 ALA A N   1 
ATOM   1324  C  CA  . ALA A 1 169 ? -3.349  5.348   -6.849  1.00 28.53  ? 169 ALA A CA  1 
ATOM   1325  C  C   . ALA A 1 169 ? -2.316  5.168   -7.956  1.00 25.59  ? 169 ALA A C   1 
ATOM   1326  O  O   . ALA A 1 169 ? -2.612  4.572   -8.993  1.00 27.92  ? 169 ALA A O   1 
ATOM   1327  C  CB  . ALA A 1 169 ? -3.899  6.774   -6.881  1.00 24.06  ? 169 ALA A CB  1 
ATOM   1328  N  N   . ASP A 1 170 ? -1.092  5.666   -7.749  1.00 26.19  ? 170 ASP A N   1 
ATOM   1329  C  CA  . ASP A 1 170 ? -0.073  5.605   -8.794  1.00 26.42  ? 170 ASP A CA  1 
ATOM   1330  C  C   . ASP A 1 170 ? 0.274   4.166   -9.178  1.00 31.15  ? 170 ASP A C   1 
ATOM   1331  O  O   . ASP A 1 170 ? 0.577   3.880   -10.345 1.00 26.17  ? 170 ASP A O   1 
ATOM   1332  C  CB  . ASP A 1 170 ? 1.175   6.341   -8.333  1.00 28.86  ? 170 ASP A CB  1 
ATOM   1333  C  CG  . ASP A 1 170 ? 2.121   6.656   -9.470  1.00 35.67  ? 170 ASP A CG  1 
ATOM   1334  O  OD1 . ASP A 1 170 ? 1.746   7.451   -10.372 1.00 30.79  ? 170 ASP A OD1 1 
ATOM   1335  O  OD2 . ASP A 1 170 ? 3.254   6.104   -9.452  1.00 35.16  ? 170 ASP A OD2 1 
ATOM   1336  N  N   . LEU A 1 171 ? 0.236   3.248   -8.217  1.00 31.19  ? 171 LEU A N   1 
ATOM   1337  C  CA  . LEU A 1 171 ? 0.495   1.837   -8.491  1.00 34.46  ? 171 LEU A CA  1 
ATOM   1338  C  C   . LEU A 1 171 ? -0.554  1.185   -9.369  1.00 27.40  ? 171 LEU A C   1 
ATOM   1339  O  O   . LEU A 1 171 ? -0.395  0.017   -9.708  1.00 36.36  ? 171 LEU A O   1 
ATOM   1340  C  CB  . LEU A 1 171 ? 0.555   1.060   -7.180  1.00 29.55  ? 171 LEU A CB  1 
ATOM   1341  C  CG  . LEU A 1 171 ? 1.857   1.320   -6.477  1.00 28.38  ? 171 LEU A CG  1 
ATOM   1342  C  CD1 . LEU A 1 171 ? 1.826   0.525   -5.220  1.00 23.71  ? 171 LEU A CD1 1 
ATOM   1343  C  CD2 . LEU A 1 171 ? 2.981   0.882   -7.385  1.00 27.89  ? 171 LEU A CD2 1 
ATOM   1344  N  N   . GLY A 1 172 ? -1.628  1.884   -9.710  1.00 30.23  ? 172 GLY A N   1 
ATOM   1345  C  CA  . GLY A 1 172 ? -2.733  1.260   -10.380 1.00 26.30  ? 172 GLY A CA  1 
ATOM   1346  C  C   . GLY A 1 172 ? -3.635  0.462   -9.465  1.00 32.91  ? 172 GLY A C   1 
ATOM   1347  O  O   . GLY A 1 172 ? -4.586  -0.161  -9.949  1.00 35.06  ? 172 GLY A O   1 
ATOM   1348  N  N   . ALA A 1 173 ? -3.377  0.463   -8.160  1.00 32.16  ? 173 ALA A N   1 
ATOM   1349  C  CA  . ALA A 1 173 ? -4.258  -0.234  -7.238  1.00 30.68  ? 173 ALA A CA  1 
ATOM   1350  C  C   . ALA A 1 173 ? -5.579  0.507   -7.096  1.00 28.37  ? 173 ALA A C   1 
ATOM   1351  O  O   . ALA A 1 173 ? -5.645  1.726   -7.224  1.00 27.06  ? 173 ALA A O   1 
ATOM   1352  C  CB  . ALA A 1 173 ? -3.596  -0.372  -5.869  1.00 32.29  ? 173 ALA A CB  1 
ATOM   1353  N  N   . THR A 1 174 ? -6.635  -0.245  -6.783  1.00 27.65  ? 174 THR A N   1 
ATOM   1354  C  CA  . THR A 1 174 ? -7.960  0.315   -6.571  1.00 24.58  ? 174 THR A CA  1 
ATOM   1355  C  C   . THR A 1 174 ? -8.430  0.237   -5.126  1.00 25.98  ? 174 THR A C   1 
ATOM   1356  O  O   . THR A 1 174 ? -9.437  0.866   -4.785  1.00 25.70  ? 174 THR A O   1 
ATOM   1357  C  CB  . THR A 1 174 ? -8.984  -0.411  -7.443  1.00 29.12  ? 174 THR A CB  1 
ATOM   1358  O  OG1 . THR A 1 174 ? -9.015  -1.791  -7.054  1.00 26.64  ? 174 THR A OG1 1 
ATOM   1359  C  CG2 . THR A 1 174 ? -8.624  -0.283  -8.900  1.00 27.59  ? 174 THR A CG2 1 
ATOM   1360  N  N   . GLY A 1 175 ? -7.749  -0.530  -4.276  1.00 28.70  ? 175 GLY A N   1 
ATOM   1361  C  CA  . GLY A 1 175 ? -8.252  -0.763  -2.939  1.00 24.37  ? 175 GLY A CA  1 
ATOM   1362  C  C   . GLY A 1 175 ? -7.345  -0.220  -1.867  1.00 20.27  ? 175 GLY A C   1 
ATOM   1363  O  O   . GLY A 1 175 ? -6.130  -0.411  -1.926  1.00 26.07  ? 175 GLY A O   1 
ATOM   1364  N  N   . ILE A 1 176 ? -7.911  0.482   -0.890  1.00 22.36  ? 176 ILE A N   1 
ATOM   1365  C  CA  . ILE A 1 176 ? -7.165  0.909   0.284   1.00 26.06  ? 176 ILE A CA  1 
ATOM   1366  C  C   . ILE A 1 176 ? -7.716  0.164   1.498   1.00 23.53  ? 176 ILE A C   1 
ATOM   1367  O  O   . ILE A 1 176 ? -8.919  0.190   1.756   1.00 24.99  ? 176 ILE A O   1 
ATOM   1368  C  CB  . ILE A 1 176 ? -7.230  2.429   0.479   1.00 26.95  ? 176 ILE A CB  1 
ATOM   1369  C  CG1 . ILE A 1 176 ? -6.523  2.825   1.771   1.00 25.33  ? 176 ILE A CG1 1 
ATOM   1370  C  CG2 . ILE A 1 176 ? -8.676  2.931   0.446   1.00 22.51  ? 176 ILE A CG2 1 
ATOM   1371  C  CD1 . ILE A 1 176 ? -5.969  4.226   1.731   1.00 29.29  ? 176 ILE A CD1 1 
ATOM   1372  N  N   . GLU A 1 177 ? -6.838  -0.511  2.227   1.00 22.73  ? 177 GLU A N   1 
ATOM   1373  C  CA  . GLU A 1 177 ? -7.165  -1.132  3.496   1.00 21.42  ? 177 GLU A CA  1 
ATOM   1374  C  C   . GLU A 1 177 ? -6.504  -0.319  4.602   1.00 23.89  ? 177 GLU A C   1 
ATOM   1375  O  O   . GLU A 1 177 ? -5.384  0.176   4.429   1.00 25.76  ? 177 GLU A O   1 
ATOM   1376  C  CB  . GLU A 1 177 ? -6.684  -2.584  3.526   1.00 25.18  ? 177 GLU A CB  1 
ATOM   1377  C  CG  . GLU A 1 177 ? -6.618  -3.223  4.906   1.00 24.13  ? 177 GLU A CG  1 
ATOM   1378  C  CD  . GLU A 1 177 ? -5.981  -4.586  4.880   1.00 29.96  ? 177 GLU A CD  1 
ATOM   1379  O  OE1 . GLU A 1 177 ? -5.291  -4.905  3.880   1.00 28.15  ? 177 GLU A OE1 1 
ATOM   1380  O  OE2 . GLU A 1 177 ? -6.159  -5.337  5.868   1.00 32.56  ? 177 GLU A OE2 1 
ATOM   1381  N  N   . ILE A 1 178 ? -7.210  -0.145  5.715   1.00 23.12  ? 178 ILE A N   1 
ATOM   1382  C  CA  . ILE A 1 178 ? -6.722  0.652   6.838   1.00 22.58  ? 178 ILE A CA  1 
ATOM   1383  C  C   . ILE A 1 178 ? -6.936  -0.105  8.145   1.00 29.76  ? 178 ILE A C   1 
ATOM   1384  O  O   . ILE A 1 178 ? -7.671  -1.094  8.221   1.00 24.15  ? 178 ILE A O   1 
ATOM   1385  C  CB  . ILE A 1 178 ? -7.395  2.038   6.922   1.00 24.67  ? 178 ILE A CB  1 
ATOM   1386  C  CG1 . ILE A 1 178 ? -8.761  1.921   7.617   1.00 22.74  ? 178 ILE A CG1 1 
ATOM   1387  C  CG2 . ILE A 1 178 ? -7.465  2.708   5.510   1.00 21.91  ? 178 ILE A CG2 1 
ATOM   1388  C  CD1 . ILE A 1 178 ? -9.427  3.211   7.900   1.00 23.61  ? 178 ILE A CD1 1 
ATOM   1389  N  N   . LEU A 1 179 ? -6.306  0.417   9.196   1.00 26.60  ? 179 LEU A N   1 
ATOM   1390  C  CA  . LEU A 1 179 ? -6.467  -0.068  10.553  1.00 24.11  ? 179 LEU A CA  1 
ATOM   1391  C  C   . LEU A 1 179 ? -7.226  1.005   11.312  1.00 27.04  ? 179 LEU A C   1 
ATOM   1392  O  O   . LEU A 1 179 ? -6.704  2.105   11.525  1.00 27.76  ? 179 LEU A O   1 
ATOM   1393  C  CB  . LEU A 1 179 ? -5.105  -0.337  11.185  1.00 22.80  ? 179 LEU A CB  1 
ATOM   1394  C  CG  . LEU A 1 179 ? -4.240  -1.391  10.521  1.00 20.23  ? 179 LEU A CG  1 
ATOM   1395  C  CD1 . LEU A 1 179 ? -2.909  -1.463  11.276  1.00 24.85  ? 179 LEU A CD1 1 
ATOM   1396  C  CD2 . LEU A 1 179 ? -4.957  -2.740  10.555  1.00 28.71  ? 179 LEU A CD2 1 
ATOM   1397  N  N   . GLY A 1 180 ? -8.464  0.705   11.688  1.00 22.81  ? 180 GLY A N   1 
ATOM   1398  C  CA  . GLY A 1 180 ? -9.301  1.694   12.350  1.00 23.85  ? 180 GLY A CA  1 
ATOM   1399  C  C   . GLY A 1 180 ? -8.630  2.520   13.434  1.00 25.52  ? 180 GLY A C   1 
ATOM   1400  O  O   . GLY A 1 180 ? -8.632  3.752   13.339  1.00 22.48  ? 180 GLY A O   1 
ATOM   1401  N  N   . GLU A 1 181 ? -8.020  1.869   14.437  1.00 25.18  ? 181 GLU A N   1 
ATOM   1402  C  CA  . GLU A 1 181 ? -7.392  2.563   15.566  1.00 27.33  ? 181 GLU A CA  1 
ATOM   1403  C  C   . GLU A 1 181 ? -6.016  3.147   15.226  1.00 24.24  ? 181 GLU A C   1 
ATOM   1404  O  O   . GLU A 1 181 ? -5.315  3.659   16.130  1.00 22.88  ? 181 GLU A O   1 
ATOM   1405  C  CB  . GLU A 1 181 ? -7.271  1.616   16.766  1.00 23.74  ? 181 GLU A CB  1 
ATOM   1406  C  CG  . GLU A 1 181 ? -8.608  1.108   17.275  1.00 28.54  ? 181 GLU A CG  1 
ATOM   1407  C  CD  . GLU A 1 181 ? -8.476  0.242   18.528  1.00 31.81  ? 181 GLU A CD  1 
ATOM   1408  O  OE1 . GLU A 1 181 ? -7.807  0.670   19.498  1.00 27.68  ? 181 GLU A OE1 1 
ATOM   1409  O  OE2 . GLU A 1 181 ? -9.032  -0.873  18.527  1.00 28.13  ? 181 GLU A OE2 1 
ATOM   1410  N  N   . ALA A 1 182 ? -5.613  3.066   13.958  1.00 20.99  ? 182 ALA A N   1 
ATOM   1411  C  CA  . ALA A 1 182 ? -4.371  3.662   13.482  1.00 19.84  ? 182 ALA A CA  1 
ATOM   1412  C  C   . ALA A 1 182 ? -4.605  4.900   12.641  1.00 24.05  ? 182 ALA A C   1 
ATOM   1413  O  O   . ALA A 1 182 ? -3.973  5.935   12.858  1.00 25.96  ? 182 ALA A O   1 
ATOM   1414  C  CB  . ALA A 1 182 ? -3.573  2.643   12.659  1.00 22.20  ? 182 ALA A CB  1 
ATOM   1415  N  N   . HIS A 1 183 ? -5.487  4.805   11.657  1.00 27.72  ? 183 HIS A N   1 
ATOM   1416  C  CA  . HIS A 1 183 ? -5.565  5.792   10.589  1.00 26.05  ? 183 HIS A CA  1 
ATOM   1417  C  C   . HIS A 1 183 ? -6.831  6.615   10.637  1.00 22.48  ? 183 HIS A C   1 
ATOM   1418  O  O   . HIS A 1 183 ? -7.022  7.471   9.772   1.00 25.83  ? 183 HIS A O   1 
ATOM   1419  C  CB  . HIS A 1 183 ? -5.454  5.087   9.235   1.00 27.15  ? 183 HIS A CB  1 
ATOM   1420  C  CG  . HIS A 1 183 ? -4.286  4.163   9.153   1.00 22.71  ? 183 HIS A CG  1 
ATOM   1421  N  ND1 . HIS A 1 183 ? -4.410  2.797   9.249   1.00 22.80  ? 183 HIS A ND1 1 
ATOM   1422  C  CD2 . HIS A 1 183 ? -2.962  4.416   9.038   1.00 20.84  ? 183 HIS A CD2 1 
ATOM   1423  C  CE1 . HIS A 1 183 ? -3.212  2.248   9.198   1.00 23.86  ? 183 HIS A CE1 1 
ATOM   1424  N  NE2 . HIS A 1 183 ? -2.315  3.208   9.070   1.00 18.45  ? 183 HIS A NE2 1 
ATOM   1425  N  N   . VAL A 1 184 ? -7.707  6.369   11.606  1.00 26.60  ? 184 VAL A N   1 
ATOM   1426  C  CA  . VAL A 1 184 ? -8.902  7.190   11.791  1.00 25.28  ? 184 VAL A CA  1 
ATOM   1427  C  C   . VAL A 1 184 ? -8.655  8.155   12.939  1.00 23.31  ? 184 VAL A C   1 
ATOM   1428  O  O   . VAL A 1 184 ? -8.685  7.750   14.115  1.00 24.15  ? 184 VAL A O   1 
ATOM   1429  C  CB  . VAL A 1 184 ? -10.155 6.339   12.045  1.00 24.90  ? 184 VAL A CB  1 
ATOM   1430  C  CG1 . VAL A 1 184 ? -11.354 7.239   12.258  1.00 23.98  ? 184 VAL A CG1 1 
ATOM   1431  C  CG2 . VAL A 1 184 ? -10.409 5.438   10.866  1.00 28.67  ? 184 VAL A CG2 1 
ATOM   1432  N  N   . PRO A 1 185 ? -8.377  9.425   12.636  1.00 23.58  ? 185 PRO A N   1 
ATOM   1433  C  CA  . PRO A 1 185 ? -8.072  10.401  13.691  1.00 23.16  ? 185 PRO A CA  1 
ATOM   1434  C  C   . PRO A 1 185 ? -9.251  10.584  14.626  1.00 23.52  ? 185 PRO A C   1 
ATOM   1435  O  O   . PRO A 1 185 ? -10.398 10.648  14.187  1.00 25.64  ? 185 PRO A O   1 
ATOM   1436  C  CB  . PRO A 1 185 ? -7.782  11.690  12.908  1.00 24.19  ? 185 PRO A CB  1 
ATOM   1437  C  CG  . PRO A 1 185 ? -7.434  11.222  11.537  1.00 21.52  ? 185 PRO A CG  1 
ATOM   1438  C  CD  . PRO A 1 185 ? -8.299  10.035  11.300  1.00 24.27  ? 185 PRO A CD  1 
ATOM   1439  N  N   . ASN A 1 186 ? -8.952  10.690  15.927  1.00 25.10  ? 186 ASN A N   1 
ATOM   1440  C  CA  . ASN A 1 186 ? -9.972  10.783  16.974  1.00 22.78  ? 186 ASN A CA  1 
ATOM   1441  C  C   . ASN A 1 186 ? -10.866 9.549   16.980  1.00 26.46  ? 186 ASN A C   1 
ATOM   1442  O  O   . ASN A 1 186 ? -12.043 9.629   17.338  1.00 28.68  ? 186 ASN A O   1 
ATOM   1443  C  CB  . ASN A 1 186 ? -10.818 12.063  16.852  1.00 25.36  ? 186 ASN A CB  1 
ATOM   1444  C  CG  . ASN A 1 186 ? -11.475 12.452  18.174  1.00 30.21  ? 186 ASN A CG  1 
ATOM   1445  O  OD1 . ASN A 1 186 ? -10.857 12.340  19.228  1.00 34.57  ? 186 ASN A OD1 1 
ATOM   1446  N  ND2 . ASN A 1 186 ? -12.740 12.884  18.126  1.00 24.40  ? 186 ASN A ND2 1 
ATOM   1447  N  N   . TYR A 1 187 ? -10.323 8.411   16.565  1.00 26.34  ? 187 TYR A N   1 
ATOM   1448  C  CA  . TYR A 1 187 ? -11.037 7.149   16.725  1.00 26.88  ? 187 TYR A CA  1 
ATOM   1449  C  C   . TYR A 1 187 ? -11.584 7.042   18.147  1.00 27.95  ? 187 TYR A C   1 
ATOM   1450  O  O   . TYR A 1 187 ? -10.882 7.375   19.108  1.00 23.82  ? 187 TYR A O   1 
ATOM   1451  C  CB  . TYR A 1 187 ? -10.124 5.958   16.424  1.00 27.81  ? 187 TYR A CB  1 
ATOM   1452  C  CG  . TYR A 1 187 ? -10.767 4.607   16.751  1.00 33.24  ? 187 TYR A CG  1 
ATOM   1453  C  CD1 . TYR A 1 187 ? -10.805 4.130   18.056  1.00 24.59  ? 187 TYR A CD1 1 
ATOM   1454  C  CD2 . TYR A 1 187 ? -11.323 3.817   15.752  1.00 24.09  ? 187 TYR A CD2 1 
ATOM   1455  C  CE1 . TYR A 1 187 ? -11.393 2.923   18.367  1.00 31.40  ? 187 TYR A CE1 1 
ATOM   1456  C  CE2 . TYR A 1 187 ? -11.914 2.578   16.058  1.00 30.43  ? 187 TYR A CE2 1 
ATOM   1457  C  CZ  . TYR A 1 187 ? -11.935 2.141   17.371  1.00 26.73  ? 187 TYR A CZ  1 
ATOM   1458  O  OH  . TYR A 1 187 ? -12.514 0.938   17.696  1.00 26.92  ? 187 TYR A OH  1 
ATOM   1459  N  N   . PRO A 1 188 ? -12.832 6.613   18.319  1.00 28.31  ? 188 PRO A N   1 
ATOM   1460  C  CA  . PRO A 1 188 ? -13.679 6.188   17.209  1.00 26.71  ? 188 PRO A CA  1 
ATOM   1461  C  C   . PRO A 1 188 ? -14.599 7.277   16.701  1.00 26.69  ? 188 PRO A C   1 
ATOM   1462  O  O   . PRO A 1 188 ? -15.611 6.930   16.130  1.00 27.28  ? 188 PRO A O   1 
ATOM   1463  C  CB  . PRO A 1 188 ? -14.497 5.055   17.832  1.00 27.59  ? 188 PRO A CB  1 
ATOM   1464  C  CG  . PRO A 1 188 ? -14.715 5.532   19.261  1.00 31.66  ? 188 PRO A CG  1 
ATOM   1465  C  CD  . PRO A 1 188 ? -13.508 6.435   19.616  1.00 30.19  ? 188 PRO A CD  1 
ATOM   1466  N  N   . ASN A 1 189 ? -14.270 8.554   16.913  1.00 27.53  ? 189 ASN A N   1 
ATOM   1467  C  CA  . ASN A 1 189 ? -15.156 9.680   16.606  1.00 23.95  ? 189 ASN A CA  1 
ATOM   1468  C  C   . ASN A 1 189 ? -14.498 10.601  15.584  1.00 25.04  ? 189 ASN A C   1 
ATOM   1469  O  O   . ASN A 1 189 ? -14.172 11.757  15.892  1.00 26.57  ? 189 ASN A O   1 
ATOM   1470  C  CB  . ASN A 1 189 ? -15.521 10.461  17.871  1.00 25.23  ? 189 ASN A CB  1 
ATOM   1471  C  CG  . ASN A 1 189 ? -16.188 9.594   18.920  1.00 32.97  ? 189 ASN A CG  1 
ATOM   1472  O  OD1 . ASN A 1 189 ? -16.964 8.704   18.582  1.00 27.98  ? 189 ASN A OD1 1 
ATOM   1473  N  ND2 . ASN A 1 189 ? -15.907 9.859   20.200  1.00 27.93  ? 189 ASN A ND2 1 
ATOM   1474  N  N   . PRO A 1 190 ? -14.305 10.140  14.350  1.00 23.54  ? 190 PRO A N   1 
ATOM   1475  C  CA  . PRO A 1 190 ? -13.711 11.031  13.352  1.00 27.42  ? 190 PRO A CA  1 
ATOM   1476  C  C   . PRO A 1 190 ? -14.637 12.210  13.109  1.00 25.73  ? 190 PRO A C   1 
ATOM   1477  O  O   . PRO A 1 190 ? -15.863 12.087  13.182  1.00 26.86  ? 190 PRO A O   1 
ATOM   1478  C  CB  . PRO A 1 190 ? -13.569 10.142  12.109  1.00 26.03  ? 190 PRO A CB  1 
ATOM   1479  C  CG  . PRO A 1 190 ? -14.730 9.193   12.231  1.00 28.22  ? 190 PRO A CG  1 
ATOM   1480  C  CD  . PRO A 1 190 ? -14.787 8.890   13.741  1.00 27.78  ? 190 PRO A CD  1 
ATOM   1481  N  N   . SER A 1 191 ? -14.037 13.369  12.854  1.00 23.55  ? 191 SER A N   1 
ATOM   1482  C  CA  . SER A 1 191 ? -14.827 14.564  12.624  1.00 27.14  ? 191 SER A CA  1 
ATOM   1483  C  C   . SER A 1 191 ? -15.569 14.450  11.297  1.00 23.43  ? 191 SER A C   1 
ATOM   1484  O  O   . SER A 1 191 ? -15.178 13.691  10.404  1.00 26.76  ? 191 SER A O   1 
ATOM   1485  C  CB  . SER A 1 191 ? -13.939 15.811  12.644  1.00 25.85  ? 191 SER A CB  1 
ATOM   1486  O  OG  . SER A 1 191 ? -13.177 15.897  11.456  1.00 24.77  ? 191 SER A OG  1 
ATOM   1487  N  N   . ASP A 1 192 ? -16.700 15.155  11.215  1.00 18.46  ? 192 ASP A N   1 
ATOM   1488  C  CA  . ASP A 1 192 ? -17.439 15.262  9.967   1.00 26.67  ? 192 ASP A CA  1 
ATOM   1489  C  C   . ASP A 1 192 ? -16.567 15.832  8.866   1.00 26.26  ? 192 ASP A C   1 
ATOM   1490  O  O   . ASP A 1 192 ? -16.724 15.481  7.693   1.00 29.82  ? 192 ASP A O   1 
ATOM   1491  C  CB  . ASP A 1 192 ? -18.668 16.151  10.160  1.00 27.60  ? 192 ASP A CB  1 
ATOM   1492  C  CG  . ASP A 1 192 ? -19.828 15.403  10.753  1.00 31.12  ? 192 ASP A CG  1 
ATOM   1493  O  OD1 . ASP A 1 192 ? -19.791 14.153  10.729  1.00 34.68  ? 192 ASP A OD1 1 
ATOM   1494  O  OD2 . ASP A 1 192 ? -20.769 16.059  11.251  1.00 36.35  ? 192 ASP A OD2 1 
ATOM   1495  N  N   . GLU A 1 193 ? -15.651 16.719  9.224   1.00 26.23  ? 193 GLU A N   1 
ATOM   1496  C  CA  . GLU A 1 193 ? -14.741 17.265  8.233   1.00 26.70  ? 193 GLU A CA  1 
ATOM   1497  C  C   . GLU A 1 193 ? -13.764 16.204  7.756   1.00 28.95  ? 193 GLU A C   1 
ATOM   1498  O  O   . GLU A 1 193 ? -13.513 16.076  6.552   1.00 28.45  ? 193 GLU A O   1 
ATOM   1499  C  CB  . GLU A 1 193 ? -14.033 18.469  8.833   1.00 32.70  ? 193 GLU A CB  1 
ATOM   1500  C  CG  . GLU A 1 193 ? -12.911 19.064  8.021   1.00 35.90  ? 193 GLU A CG  1 
ATOM   1501  C  CD  . GLU A 1 193 ? -12.406 20.351  8.661   1.00 46.10  ? 193 GLU A CD  1 
ATOM   1502  O  OE1 . GLU A 1 193 ? -11.713 20.280  9.705   1.00 44.22  ? 193 GLU A OE1 1 
ATOM   1503  O  OE2 . GLU A 1 193 ? -12.735 21.434  8.131   1.00 52.56  ? 193 GLU A OE2 1 
ATOM   1504  N  N   . TRP A 1 194 ? -13.231 15.405  8.681   1.00 25.54  ? 194 TRP A N   1 
ATOM   1505  C  CA  . TRP A 1 194 ? -12.358 14.304  8.279   1.00 29.11  ? 194 TRP A CA  1 
ATOM   1506  C  C   . TRP A 1 194 ? -13.069 13.326  7.348   1.00 24.66  ? 194 TRP A C   1 
ATOM   1507  O  O   . TRP A 1 194 ? -12.481 12.856  6.365   1.00 26.03  ? 194 TRP A O   1 
ATOM   1508  C  CB  . TRP A 1 194 ? -11.824 13.551  9.499   1.00 26.70  ? 194 TRP A CB  1 
ATOM   1509  C  CG  . TRP A 1 194 ? -10.750 12.630  9.061   1.00 26.01  ? 194 TRP A CG  1 
ATOM   1510  C  CD1 . TRP A 1 194 ? -9.447  12.947  8.861   1.00 25.15  ? 194 TRP A CD1 1 
ATOM   1511  C  CD2 . TRP A 1 194 ? -10.893 11.259  8.686   1.00 24.93  ? 194 TRP A CD2 1 
ATOM   1512  N  NE1 . TRP A 1 194 ? -8.763  11.866  8.394   1.00 24.56  ? 194 TRP A NE1 1 
ATOM   1513  C  CE2 . TRP A 1 194 ? -9.629  10.810  8.281   1.00 22.77  ? 194 TRP A CE2 1 
ATOM   1514  C  CE3 . TRP A 1 194 ? -11.967 10.359  8.675   1.00 24.57  ? 194 TRP A CE3 1 
ATOM   1515  C  CZ2 . TRP A 1 194 ? -9.397  9.497   7.880   1.00 24.68  ? 194 TRP A CZ2 1 
ATOM   1516  C  CZ3 . TRP A 1 194 ? -11.737 9.056   8.258   1.00 23.09  ? 194 TRP A CZ3 1 
ATOM   1517  C  CH2 . TRP A 1 194 ? -10.465 8.636   7.880   1.00 25.37  ? 194 TRP A CH2 1 
ATOM   1518  N  N   . VAL A 1 195 ? -14.322 12.983  7.656   1.00 28.69  ? 195 VAL A N   1 
ATOM   1519  C  CA  . VAL A 1 195 ? -15.024 11.972  6.870   1.00 25.95  ? 195 VAL A CA  1 
ATOM   1520  C  C   . VAL A 1 195 ? -15.343 12.518  5.484   1.00 27.55  ? 195 VAL A C   1 
ATOM   1521  O  O   . VAL A 1 195 ? -15.129 11.845  4.467   1.00 29.01  ? 195 VAL A O   1 
ATOM   1522  C  CB  . VAL A 1 195 ? -16.289 11.496  7.609   1.00 27.19  ? 195 VAL A CB  1 
ATOM   1523  C  CG1 . VAL A 1 195 ? -17.118 10.613  6.718   1.00 26.53  ? 195 VAL A CG1 1 
ATOM   1524  C  CG2 . VAL A 1 195 ? -15.911 10.731  8.917   1.00 22.73  ? 195 VAL A CG2 1 
ATOM   1525  N  N   . GLU A 1 196 ? -15.860 13.746  5.424   1.00 26.21  ? 196 GLU A N   1 
ATOM   1526  C  CA  . GLU A 1 196 ? -16.026 14.420  4.141   1.00 30.37  ? 196 GLU A CA  1 
ATOM   1527  C  C   . GLU A 1 196 ? -14.719 14.413  3.343   1.00 30.50  ? 196 GLU A C   1 
ATOM   1528  O  O   . GLU A 1 196 ? -14.705 14.079  2.152   1.00 31.38  ? 196 GLU A O   1 
ATOM   1529  C  CB  . GLU A 1 196 ? -16.533 15.853  4.362   1.00 38.84  ? 196 GLU A CB  1 
ATOM   1530  C  CG  . GLU A 1 196 ? -17.041 16.572  3.090   1.00 41.52  ? 196 GLU A CG  1 
ATOM   1531  C  CD  . GLU A 1 196 ? -17.437 18.035  3.325   1.00 53.56  ? 196 GLU A CD  1 
ATOM   1532  O  OE1 . GLU A 1 196 ? -18.581 18.285  3.783   1.00 49.09  ? 196 GLU A OE1 1 
ATOM   1533  O  OE2 . GLU A 1 196 ? -16.613 18.936  3.028   1.00 55.78  ? 196 GLU A OE2 1 
ATOM   1534  N  N   . GLN A 1 197 ? -13.600 14.753  3.984   1.00 30.05  ? 197 GLN A N   1 
ATOM   1535  C  CA  . GLN A 1 197 ? -12.335 14.739  3.247   1.00 28.29  ? 197 GLN A CA  1 
ATOM   1536  C  C   . GLN A 1 197 ? -11.953 13.328  2.824   1.00 31.64  ? 197 GLN A C   1 
ATOM   1537  O  O   . GLN A 1 197 ? -11.394 13.144  1.740   1.00 31.64  ? 197 GLN A O   1 
ATOM   1538  C  CB  . GLN A 1 197 ? -11.219 15.364  4.084   1.00 30.05  ? 197 GLN A CB  1 
ATOM   1539  C  CG  . GLN A 1 197 ? -9.779  15.200  3.527   1.00 36.83  ? 197 GLN A CG  1 
ATOM   1540  C  CD  . GLN A 1 197 ? -9.485  15.934  2.190   1.00 38.16  ? 197 GLN A CD  1 
ATOM   1541  O  OE1 . GLN A 1 197 ? -10.392 16.344  1.457   1.00 41.67  ? 197 GLN A OE1 1 
ATOM   1542  N  NE2 . GLN A 1 197 ? -8.194  16.082  1.876   1.00 36.87  ? 197 GLN A NE2 1 
ATOM   1543  N  N   . TRP A 1 198 ? -12.256 12.326  3.656   1.00 28.74  ? 198 TRP A N   1 
ATOM   1544  C  CA  . TRP A 1 198 ? -11.986 10.931  3.305   1.00 28.92  ? 198 TRP A CA  1 
ATOM   1545  C  C   . TRP A 1 198 ? -12.648 10.546  1.985   1.00 23.17  ? 198 TRP A C   1 
ATOM   1546  O  O   . TRP A 1 198 ? -11.988 10.039  1.074   1.00 27.28  ? 198 TRP A O   1 
ATOM   1547  C  CB  . TRP A 1 198 ? -12.445 10.037  4.459   1.00 25.09  ? 198 TRP A CB  1 
ATOM   1548  C  CG  . TRP A 1 198 ? -12.584 8.546   4.215   1.00 26.51  ? 198 TRP A CG  1 
ATOM   1549  C  CD1 . TRP A 1 198 ? -13.752 7.856   4.110   1.00 24.58  ? 198 TRP A CD1 1 
ATOM   1550  C  CD2 . TRP A 1 198 ? -11.535 7.567   4.152   1.00 20.50  ? 198 TRP A CD2 1 
ATOM   1551  N  NE1 . TRP A 1 198 ? -13.500 6.518   3.950   1.00 23.35  ? 198 TRP A NE1 1 
ATOM   1552  C  CE2 . TRP A 1 198 ? -12.148 6.313   3.972   1.00 24.21  ? 198 TRP A CE2 1 
ATOM   1553  C  CE3 . TRP A 1 198 ? -10.142 7.631   4.214   1.00 18.90  ? 198 TRP A CE3 1 
ATOM   1554  C  CZ2 . TRP A 1 198 ? -11.417 5.137   3.846   1.00 23.62  ? 198 TRP A CZ2 1 
ATOM   1555  C  CZ3 . TRP A 1 198 ? -9.420  6.473   4.100   1.00 22.91  ? 198 TRP A CZ3 1 
ATOM   1556  C  CH2 . TRP A 1 198 ? -10.055 5.235   3.914   1.00 25.59  ? 198 TRP A CH2 1 
ATOM   1557  N  N   . PHE A 1 199 ? -13.945 10.802  1.841   1.00 30.73  ? 199 PHE A N   1 
ATOM   1558  C  CA  . PHE A 1 199 ? -14.604 10.416  0.587   1.00 26.49  ? 199 PHE A CA  1 
ATOM   1559  C  C   . PHE A 1 199 ? -14.149 11.276  -0.582  1.00 28.41  ? 199 PHE A C   1 
ATOM   1560  O  O   . PHE A 1 199 ? -14.065 10.789  -1.718  1.00 33.60  ? 199 PHE A O   1 
ATOM   1561  C  CB  . PHE A 1 199 ? -16.119 10.472  0.757   1.00 29.50  ? 199 PHE A CB  1 
ATOM   1562  C  CG  . PHE A 1 199 ? -16.664 9.321   1.554   1.00 24.50  ? 199 PHE A CG  1 
ATOM   1563  C  CD1 . PHE A 1 199 ? -16.625 8.032   1.033   1.00 25.04  ? 199 PHE A CD1 1 
ATOM   1564  C  CD2 . PHE A 1 199 ? -17.180 9.513   2.814   1.00 22.28  ? 199 PHE A CD2 1 
ATOM   1565  C  CE1 . PHE A 1 199 ? -17.116 6.945   1.767   1.00 26.36  ? 199 PHE A CE1 1 
ATOM   1566  C  CE2 . PHE A 1 199 ? -17.674 8.437   3.560   1.00 23.59  ? 199 PHE A CE2 1 
ATOM   1567  C  CZ  . PHE A 1 199 ? -17.643 7.153   3.036   1.00 26.85  ? 199 PHE A CZ  1 
ATOM   1568  N  N   . ALA A 1 200 ? -13.814 12.538  -0.333  1.00 28.47  ? 200 ALA A N   1 
ATOM   1569  C  CA  . ALA A 1 200 ? -13.218 13.339  -1.398  1.00 30.14  ? 200 ALA A CA  1 
ATOM   1570  C  C   . ALA A 1 200 ? -11.908 12.722  -1.870  1.00 28.93  ? 200 ALA A C   1 
ATOM   1571  O  O   . ALA A 1 200 ? -11.665 12.606  -3.080  1.00 27.17  ? 200 ALA A O   1 
ATOM   1572  C  CB  . ALA A 1 200 ? -13.017 14.773  -0.927  1.00 23.02  ? 200 ALA A CB  1 
ATOM   1573  N  N   . LEU A 1 201 ? -11.072 12.275  -0.930  1.00 24.01  ? 201 LEU A N   1 
ATOM   1574  C  CA  . LEU A 1 201 ? -9.787  11.690  -1.302  1.00 25.47  ? 201 LEU A CA  1 
ATOM   1575  C  C   . LEU A 1 201 ? -9.959  10.408  -2.113  1.00 23.71  ? 201 LEU A C   1 
ATOM   1576  O  O   . LEU A 1 201 ? -9.235  10.191  -3.088  1.00 26.75  ? 201 LEU A O   1 
ATOM   1577  C  CB  . LEU A 1 201 ? -8.956  11.420  -0.051  1.00 24.80  ? 201 LEU A CB  1 
ATOM   1578  C  CG  . LEU A 1 201 ? -8.399  12.703  0.570   1.00 26.30  ? 201 LEU A CG  1 
ATOM   1579  C  CD1 . LEU A 1 201 ? -7.667  12.408  1.868   1.00 24.50  ? 201 LEU A CD1 1 
ATOM   1580  C  CD2 . LEU A 1 201 ? -7.507  13.437  -0.439  1.00 25.86  ? 201 LEU A CD2 1 
ATOM   1581  N  N   . LEU A 1 202 ? -10.878 9.532   -1.696  1.00 23.93  ? 202 LEU A N   1 
ATOM   1582  C  CA  . LEU A 1 202 ? -11.162 8.309   -2.446  1.00 29.13  ? 202 LEU A CA  1 
ATOM   1583  C  C   . LEU A 1 202 ? -11.588 8.646   -3.869  1.00 28.30  ? 202 LEU A C   1 
ATOM   1584  O  O   . LEU A 1 202 ? -11.102 8.047   -4.841  1.00 31.24  ? 202 LEU A O   1 
ATOM   1585  C  CB  . LEU A 1 202 ? -12.259 7.491   -1.736  1.00 21.14  ? 202 LEU A CB  1 
ATOM   1586  C  CG  . LEU A 1 202 ? -11.988 6.959   -0.312  1.00 25.69  ? 202 LEU A CG  1 
ATOM   1587  C  CD1 . LEU A 1 202 ? -13.270 6.475   0.339   1.00 25.23  ? 202 LEU A CD1 1 
ATOM   1588  C  CD2 . LEU A 1 202 ? -10.971 5.825   -0.314  1.00 22.49  ? 202 LEU A CD2 1 
ATOM   1589  N  N   . SER A 1 203 ? -12.496 9.616   -4.007  1.00 24.70  ? 203 SER A N   1 
ATOM   1590  C  CA  . SER A 1 203 ? -12.935 10.051  -5.330  1.00 32.44  ? 203 SER A CA  1 
ATOM   1591  C  C   . SER A 1 203 ? -11.760 10.562  -6.150  1.00 29.01  ? 203 SER A C   1 
ATOM   1592  O  O   . SER A 1 203 ? -11.589 10.179  -7.308  1.00 29.68  ? 203 SER A O   1 
ATOM   1593  C  CB  . SER A 1 203 ? -14.026 11.124  -5.195  1.00 32.03  ? 203 SER A CB  1 
ATOM   1594  O  OG  . SER A 1 203 ? -14.639 11.403  -6.440  1.00 33.51  ? 203 SER A OG  1 
ATOM   1595  N  N   . THR A 1 204 ? -10.911 11.400  -5.549  1.00 31.47  ? 204 THR A N   1 
ATOM   1596  C  CA  . THR A 1 204 ? -9.800  11.977  -6.300  1.00 28.39  ? 204 THR A CA  1 
ATOM   1597  C  C   . THR A 1 204 ? -8.841  10.907  -6.808  1.00 29.41  ? 204 THR A C   1 
ATOM   1598  O  O   . THR A 1 204 ? -8.404  10.958  -7.959  1.00 26.58  ? 204 THR A O   1 
ATOM   1599  C  CB  . THR A 1 204 ? -9.052  13.000  -5.447  1.00 26.19  ? 204 THR A CB  1 
ATOM   1600  O  OG1 . THR A 1 204 ? -9.917  14.106  -5.184  1.00 31.23  ? 204 THR A OG1 1 
ATOM   1601  C  CG2 . THR A 1 204 ? -7.827  13.511  -6.183  1.00 27.35  ? 204 THR A CG2 1 
ATOM   1602  N  N   . TYR A 1 205 ? -8.470  9.940   -5.968  1.00 29.83  ? 205 TYR A N   1 
ATOM   1603  C  CA  . TYR A 1 205 ? -7.438  8.996   -6.378  1.00 26.35  ? 205 TYR A CA  1 
ATOM   1604  C  C   . TYR A 1 205 ? -8.006  7.675   -6.907  1.00 26.87  ? 205 TYR A C   1 
ATOM   1605  O  O   . TYR A 1 205 ? -7.231  6.777   -7.247  1.00 27.64  ? 205 TYR A O   1 
ATOM   1606  C  CB  . TYR A 1 205 ? -6.448  8.770   -5.233  1.00 23.82  ? 205 TYR A CB  1 
ATOM   1607  C  CG  . TYR A 1 205 ? -5.717  10.045  -4.888  1.00 23.33  ? 205 TYR A CG  1 
ATOM   1608  C  CD1 . TYR A 1 205 ? -4.612  10.445  -5.627  1.00 26.32  ? 205 TYR A CD1 1 
ATOM   1609  C  CD2 . TYR A 1 205 ? -6.169  10.885  -3.861  1.00 29.15  ? 205 TYR A CD2 1 
ATOM   1610  C  CE1 . TYR A 1 205 ? -3.949  11.626  -5.348  1.00 29.30  ? 205 TYR A CE1 1 
ATOM   1611  C  CE2 . TYR A 1 205 ? -5.504  12.081  -3.564  1.00 24.96  ? 205 TYR A CE2 1 
ATOM   1612  C  CZ  . TYR A 1 205 ? -4.398  12.443  -4.320  1.00 24.07  ? 205 TYR A CZ  1 
ATOM   1613  O  OH  . TYR A 1 205 ? -3.715  13.611  -4.057  1.00 31.78  ? 205 TYR A OH  1 
ATOM   1614  N  N   . GLY A 1 206 ? -9.328  7.560   -7.037  1.00 27.35  ? 206 GLY A N   1 
ATOM   1615  C  CA  . GLY A 1 206 ? -9.916  6.376   -7.636  1.00 28.05  ? 206 GLY A CA  1 
ATOM   1616  C  C   . GLY A 1 206 ? -9.849  5.151   -6.755  1.00 31.02  ? 206 GLY A C   1 
ATOM   1617  O  O   . GLY A 1 206 ? -9.768  4.022   -7.270  1.00 24.16  ? 206 GLY A O   1 
ATOM   1618  N  N   . LEU A 1 207 ? -9.883  5.336   -5.438  1.00 26.55  ? 207 LEU A N   1 
ATOM   1619  C  CA  . LEU A 1 207 ? -9.718  4.227   -4.512  1.00 27.08  ? 207 LEU A CA  1 
ATOM   1620  C  C   . LEU A 1 207 ? -11.048 3.813   -3.886  1.00 29.01  ? 207 LEU A C   1 
ATOM   1621  O  O   . LEU A 1 207 ? -11.952 4.630   -3.686  1.00 30.61  ? 207 LEU A O   1 
ATOM   1622  C  CB  . LEU A 1 207 ? -8.705  4.594   -3.425  1.00 29.54  ? 207 LEU A CB  1 
ATOM   1623  C  CG  . LEU A 1 207 ? -7.297  4.917   -3.950  1.00 32.05  ? 207 LEU A CG  1 
ATOM   1624  C  CD1 . LEU A 1 207 ? -6.287  5.136   -2.814  1.00 26.74  ? 207 LEU A CD1 1 
ATOM   1625  C  CD2 . LEU A 1 207 ? -6.797  3.845   -4.946  1.00 29.30  ? 207 LEU A CD2 1 
ATOM   1626  N  N   . GLU A 1 208 ? -11.161 2.526   -3.571  1.00 26.91  ? 208 GLU A N   1 
ATOM   1627  C  CA  . GLU A 1 208 ? -12.333 2.111   -2.826  1.00 23.33  ? 208 GLU A CA  1 
ATOM   1628  C  C   . GLU A 1 208 ? -11.907 1.469   -1.511  1.00 25.23  ? 208 GLU A C   1 
ATOM   1629  O  O   . GLU A 1 208 ? -10.892 0.770   -1.470  1.00 29.65  ? 208 GLU A O   1 
ATOM   1630  C  CB  . GLU A 1 208 ? -13.201 1.135   -3.650  1.00 32.65  ? 208 GLU A CB  1 
ATOM   1631  C  CG  . GLU A 1 208 ? -12.620 -0.269  -3.806  1.00 35.14  ? 208 GLU A CG  1 
ATOM   1632  C  CD  . GLU A 1 208 ? -13.002 -0.971  -5.111  1.00 42.47  ? 208 GLU A CD  1 
ATOM   1633  O  OE1 . GLU A 1 208 ? -13.179 -0.299  -6.166  1.00 46.06  ? 208 GLU A OE1 1 
ATOM   1634  O  OE2 . GLU A 1 208 ? -13.121 -2.219  -5.061  1.00 39.74  ? 208 GLU A OE2 1 
ATOM   1635  N  N   . PRO A 1 209 ? -12.617 1.725   -0.417  1.00 25.21  ? 209 PRO A N   1 
ATOM   1636  C  CA  . PRO A 1 209 ? -12.227 1.121   0.867   1.00 29.13  ? 209 PRO A CA  1 
ATOM   1637  C  C   . PRO A 1 209 ? -12.545 -0.368  0.881   1.00 28.74  ? 209 PRO A C   1 
ATOM   1638  O  O   . PRO A 1 209 ? -13.640 -0.787  0.499   1.00 31.72  ? 209 PRO A O   1 
ATOM   1639  C  CB  . PRO A 1 209 ? -13.067 1.890   1.906   1.00 21.77  ? 209 PRO A CB  1 
ATOM   1640  C  CG  . PRO A 1 209 ? -13.683 3.045   1.156   1.00 21.37  ? 209 PRO A CG  1 
ATOM   1641  C  CD  . PRO A 1 209 ? -13.760 2.642   -0.277  1.00 24.54  ? 209 PRO A CD  1 
ATOM   1642  N  N   . THR A 1 210 ? -11.586 -1.169  1.349   1.00 25.86  ? 210 THR A N   1 
ATOM   1643  C  CA  . THR A 1 210 ? -11.733 -2.611  1.300   1.00 28.60  ? 210 THR A CA  1 
ATOM   1644  C  C   . THR A 1 210 ? -11.869 -3.142  2.714   1.00 28.18  ? 210 THR A C   1 
ATOM   1645  O  O   . THR A 1 210 ? -12.996 -3.226  3.236   1.00 26.81  ? 210 THR A O   1 
ATOM   1646  C  CB  . THR A 1 210 ? -10.574 -3.234  0.507   1.00 28.11  ? 210 THR A CB  1 
ATOM   1647  O  OG1 . THR A 1 210 ? -9.322  -2.990  1.157   1.00 27.95  ? 210 THR A OG1 1 
ATOM   1648  C  CG2 . THR A 1 210 ? -10.520 -2.630  -0.867  1.00 29.35  ? 210 THR A CG2 1 
ATOM   1649  N  N   . ASN A 1 211 ? -10.783 -3.512  3.378   1.00 29.11  ? 211 ASN A N   1 
ATOM   1650  C  CA  . ASN A 1 211 ? -10.788 -4.070  4.723   1.00 27.24  ? 211 ASN A CA  1 
ATOM   1651  C  C   . ASN A 1 211 ? -10.457 -2.982  5.735   1.00 22.81  ? 211 ASN A C   1 
ATOM   1652  O  O   . ASN A 1 211 ? -9.527  -2.203  5.525   1.00 20.23  ? 211 ASN A O   1 
ATOM   1653  C  CB  . ASN A 1 211 ? -9.738  -5.181  4.816   1.00 21.61  ? 211 ASN A CB  1 
ATOM   1654  C  CG  . ASN A 1 211 ? -9.667  -5.807  6.178   1.00 24.61  ? 211 ASN A CG  1 
ATOM   1655  O  OD1 . ASN A 1 211 ? -10.699 -6.058  6.796   1.00 32.50  ? 211 ASN A OD1 1 
ATOM   1656  N  ND2 . ASN A 1 211 ? -8.451  -6.107  6.643   1.00 25.13  ? 211 ASN A ND2 1 
ATOM   1657  N  N   . MET A 1 212 ? -11.185 -2.934  6.834   1.00 20.95  ? 212 MET A N   1 
ATOM   1658  C  CA  . MET A 1 212 ? -10.778 -2.090  7.952   1.00 25.03  ? 212 MET A CA  1 
ATOM   1659  C  C   . MET A 1 212 ? -10.397 -3.014  9.101   1.00 28.87  ? 212 MET A C   1 
ATOM   1660  O  O   . MET A 1 212 ? -11.242 -3.753  9.618   1.00 31.38  ? 212 MET A O   1 
ATOM   1661  C  CB  . MET A 1 212 ? -11.869 -1.103  8.362   1.00 23.38  ? 212 MET A CB  1 
ATOM   1662  C  CG  . MET A 1 212 ? -11.453 -0.256  9.568   1.00 27.83  ? 212 MET A CG  1 
ATOM   1663  S  SD  . MET A 1 212 ? -12.738 0.733   10.334  1.00 25.25  ? 212 MET A SD  1 
ATOM   1664  C  CE  . MET A 1 212 ? -13.110 -0.211  11.812  1.00 24.00  ? 212 MET A CE  1 
ATOM   1665  N  N   . GLY A 1 213 ? -9.123  -3.005  9.476   1.00 28.63  ? 213 GLY A N   1 
ATOM   1666  C  CA  . GLY A 1 213 ? -8.693  -3.802  10.612  1.00 25.16  ? 213 GLY A CA  1 
ATOM   1667  C  C   . GLY A 1 213 ? -9.182  -3.229  11.931  1.00 31.07  ? 213 GLY A C   1 
ATOM   1668  O  O   . GLY A 1 213 ? -9.323  -2.011  12.105  1.00 26.87  ? 213 GLY A O   1 
ATOM   1669  N  N   . SER A 1 214 ? -9.482  -4.135  12.865  1.00 30.12  ? 214 SER A N   1 
ATOM   1670  C  CA  . SER A 1 214 ? -9.999  -3.766  14.176  1.00 25.29  ? 214 SER A CA  1 
ATOM   1671  C  C   . SER A 1 214 ? -9.575  -4.823  15.183  1.00 25.63  ? 214 SER A C   1 
ATOM   1672  O  O   . SER A 1 214 ? -9.043  -5.874  14.825  1.00 28.49  ? 214 SER A O   1 
ATOM   1673  C  CB  . SER A 1 214 ? -11.519 -3.584  14.157  1.00 29.33  ? 214 SER A CB  1 
ATOM   1674  O  OG  . SER A 1 214 ? -12.188 -4.818  14.241  1.00 30.84  ? 214 SER A OG  1 
ATOM   1675  N  N   . TRP A 1 215 ? -9.757  -4.518  16.462  1.00 28.34  ? 215 TRP A N   1 
ATOM   1676  C  CA  . TRP A 1 215 ? -9.292  -5.410  17.505  1.00 29.97  ? 215 TRP A CA  1 
ATOM   1677  C  C   . TRP A 1 215 ? -10.413 -5.744  18.477  1.00 26.95  ? 215 TRP A C   1 
ATOM   1678  O  O   . TRP A 1 215 ? -11.366 -4.979  18.666  1.00 29.32  ? 215 TRP A O   1 
ATOM   1679  C  CB  . TRP A 1 215 ? -8.101  -4.822  18.284  1.00 26.70  ? 215 TRP A CB  1 
ATOM   1680  C  CG  . TRP A 1 215 ? -6.867  -4.760  17.500  1.00 27.57  ? 215 TRP A CG  1 
ATOM   1681  C  CD1 . TRP A 1 215 ? -5.792  -5.586  17.605  1.00 31.75  ? 215 TRP A CD1 1 
ATOM   1682  C  CD2 . TRP A 1 215 ? -6.549  -3.818  16.467  1.00 27.71  ? 215 TRP A CD2 1 
ATOM   1683  N  NE1 . TRP A 1 215 ? -4.825  -5.232  16.686  1.00 28.12  ? 215 TRP A NE1 1 
ATOM   1684  C  CE2 . TRP A 1 215 ? -5.269  -4.148  15.979  1.00 27.55  ? 215 TRP A CE2 1 
ATOM   1685  C  CE3 . TRP A 1 215 ? -7.228  -2.740  15.898  1.00 29.42  ? 215 TRP A CE3 1 
ATOM   1686  C  CZ2 . TRP A 1 215 ? -4.646  -3.424  14.967  1.00 25.32  ? 215 TRP A CZ2 1 
ATOM   1687  C  CZ3 . TRP A 1 215 ? -6.610  -2.029  14.884  1.00 25.06  ? 215 TRP A CZ3 1 
ATOM   1688  C  CH2 . TRP A 1 215 ? -5.340  -2.384  14.425  1.00 26.89  ? 215 TRP A CH2 1 
ATOM   1689  N  N   . ILE A 1 216 ? -10.271 -6.904  19.096  1.00 29.51  ? 216 ILE A N   1 
ATOM   1690  C  CA  . ILE A 1 216 ? -11.030 -7.282  20.278  1.00 27.13  ? 216 ILE A CA  1 
ATOM   1691  C  C   . ILE A 1 216 ? -9.976  -7.523  21.348  1.00 29.12  ? 216 ILE A C   1 
ATOM   1692  O  O   . ILE A 1 216 ? -9.431  -8.624  21.461  1.00 24.24  ? 216 ILE A O   1 
ATOM   1693  C  CB  . ILE A 1 216 ? -11.902 -8.518  20.050  1.00 29.67  ? 216 ILE A CB  1 
ATOM   1694  C  CG1 . ILE A 1 216 ? -12.898 -8.252  18.921  1.00 34.55  ? 216 ILE A CG1 1 
ATOM   1695  C  CG2 . ILE A 1 216 ? -12.623 -8.914  21.320  1.00 26.21  ? 216 ILE A CG2 1 
ATOM   1696  C  CD1 . ILE A 1 216 ? -14.077 -7.417  19.320  1.00 30.93  ? 216 ILE A CD1 1 
ATOM   1697  N  N   . ASP A 1 217 ? -9.656  -6.476  22.116  1.00 29.06  ? 217 ASP A N   1 
ATOM   1698  C  CA  . ASP A 1 217 ? -8.556  -6.512  23.090  1.00 30.41  ? 217 ASP A CA  1 
ATOM   1699  C  C   . ASP A 1 217 ? -9.051  -7.117  24.394  1.00 28.15  ? 217 ASP A C   1 
ATOM   1700  O  O   . ASP A 1 217 ? -9.495  -6.409  25.304  1.00 23.85  ? 217 ASP A O   1 
ATOM   1701  C  CB  . ASP A 1 217 ? -7.998  -5.118  23.342  1.00 29.89  ? 217 ASP A CB  1 
ATOM   1702  C  CG  . ASP A 1 217 ? -7.483  -4.462  22.090  1.00 29.73  ? 217 ASP A CG  1 
ATOM   1703  O  OD1 . ASP A 1 217 ? -6.599  -5.039  21.417  1.00 32.67  ? 217 ASP A OD1 1 
ATOM   1704  O  OD2 . ASP A 1 217 ? -7.988  -3.369  21.785  1.00 23.36  ? 217 ASP A OD2 1 
ATOM   1705  N  N   . THR A 1 218 ? -8.944  -8.441  24.491  1.00 27.49  ? 218 THR A N   1 
ATOM   1706  C  CA  . THR A 1 218 ? -9.465  -9.157  25.656  1.00 29.87  ? 218 THR A CA  1 
ATOM   1707  C  C   . THR A 1 218 ? -8.746  -8.770  26.949  1.00 27.94  ? 218 THR A C   1 
ATOM   1708  O  O   . THR A 1 218 ? -9.333  -8.859  28.034  1.00 29.49  ? 218 THR A O   1 
ATOM   1709  C  CB  . THR A 1 218 ? -9.339  -10.660 25.423  1.00 27.38  ? 218 THR A CB  1 
ATOM   1710  O  OG1 . THR A 1 218 ? -7.971  -10.966 25.141  1.00 33.74  ? 218 THR A OG1 1 
ATOM   1711  C  CG2 . THR A 1 218 ? -10.199 -11.083 24.219  1.00 25.85  ? 218 THR A CG2 1 
ATOM   1712  N  N   . ARG A 1 219 ? -7.478  -8.357  26.862  1.00 30.60  ? 219 ARG A N   1 
ATOM   1713  C  CA  . ARG A 1 219 ? -6.692  -8.007  28.041  1.00 32.59  ? 219 ARG A CA  1 
ATOM   1714  C  C   . ARG A 1 219 ? -6.841  -6.539  28.434  1.00 26.05  ? 219 ARG A C   1 
ATOM   1715  O  O   . ARG A 1 219 ? -6.018  -6.024  29.199  1.00 27.85  ? 219 ARG A O   1 
ATOM   1716  C  CB  . ARG A 1 219 ? -5.217  -8.345  27.827  1.00 29.03  ? 219 ARG A CB  1 
ATOM   1717  C  CG  . ARG A 1 219 ? -4.994  -9.726  27.280  1.00 26.65  ? 219 ARG A CG  1 
ATOM   1718  C  CD  . ARG A 1 219 ? -3.563  -10.176 27.502  1.00 30.80  ? 219 ARG A CD  1 
ATOM   1719  N  NE  . ARG A 1 219 ? -3.383  -11.540 27.029  1.00 37.83  ? 219 ARG A NE  1 
ATOM   1720  C  CZ  . ARG A 1 219 ? -2.480  -11.921 26.138  1.00 38.78  ? 219 ARG A CZ  1 
ATOM   1721  N  NH1 . ARG A 1 219 ? -1.570  -11.082 25.675  1.00 36.00  ? 219 ARG A NH1 1 
ATOM   1722  N  NH2 . ARG A 1 219 ? -2.486  -13.180 25.707  1.00 39.50  ? 219 ARG A NH2 1 
ATOM   1723  N  N   . LEU A 1 220 ? -7.899  -5.886  27.952  1.00 28.42  ? 220 LEU A N   1 
ATOM   1724  C  CA  . LEU A 1 220 ? -8.179  -4.490  28.251  1.00 30.63  ? 220 LEU A CA  1 
ATOM   1725  C  C   . LEU A 1 220 ? -7.868  -4.132  29.684  1.00 30.83  ? 220 LEU A C   1 
ATOM   1726  O  O   . LEU A 1 220 ? -7.242  -3.100  29.957  1.00 31.12  ? 220 LEU A O   1 
ATOM   1727  C  CB  . LEU A 1 220 ? -9.648  -4.185  27.950  1.00 29.36  ? 220 LEU A CB  1 
ATOM   1728  C  CG  . LEU A 1 220 ? -9.911  -2.688  27.755  1.00 30.02  ? 220 LEU A CG  1 
ATOM   1729  C  CD1 . LEU A 1 220 ? -8.919  -2.110  26.758  1.00 27.80  ? 220 LEU A CD1 1 
ATOM   1730  C  CD2 . LEU A 1 220 ? -11.343 -2.438  27.316  1.00 29.44  ? 220 LEU A CD2 1 
ATOM   1731  N  N   . HIS A 1 221 ? -8.304  -4.960  30.623  1.00 32.03  ? 221 HIS A N   1 
ATOM   1732  C  CA  . HIS A 1 221 ? -8.133  -4.627  32.029  1.00 29.72  ? 221 HIS A CA  1 
ATOM   1733  C  C   . HIS A 1 221 ? -7.435  -5.747  32.776  1.00 33.44  ? 221 HIS A C   1 
ATOM   1734  O  O   . HIS A 1 221 ? -7.820  -6.108  33.886  1.00 35.21  ? 221 HIS A O   1 
ATOM   1735  C  CB  . HIS A 1 221 ? -9.472  -4.300  32.672  1.00 38.61  ? 221 HIS A CB  1 
ATOM   1736  C  CG  . HIS A 1 221 ? -10.074 -3.020  32.194  1.00 34.61  ? 221 HIS A CG  1 
ATOM   1737  N  ND1 . HIS A 1 221 ? -9.687  -1.791  32.684  1.00 35.57  ? 221 HIS A ND1 1 
ATOM   1738  C  CD2 . HIS A 1 221 ? -11.036 -2.775  31.273  1.00 32.77  ? 221 HIS A CD2 1 
ATOM   1739  C  CE1 . HIS A 1 221 ? -10.387 -0.846  32.085  1.00 35.54  ? 221 HIS A CE1 1 
ATOM   1740  N  NE2 . HIS A 1 221 ? -11.214 -1.416  31.227  1.00 34.06  ? 221 HIS A NE2 1 
ATOM   1741  N  N   . SER A 1 222 ? -6.400  -6.321  32.173  1.00 35.51  ? 222 SER A N   1 
ATOM   1742  C  CA  . SER A 1 222 ? -5.700  -7.449  32.772  1.00 37.06  ? 222 SER A CA  1 
ATOM   1743  C  C   . SER A 1 222 ? -4.707  -7.044  33.866  1.00 38.42  ? 222 SER A C   1 
ATOM   1744  O  O   . SER A 1 222 ? -4.312  -7.906  34.659  1.00 42.76  ? 222 SER A O   1 
ATOM   1745  C  CB  . SER A 1 222 ? -4.997  -8.267  31.671  1.00 33.46  ? 222 SER A CB  1 
ATOM   1746  O  OG  . SER A 1 222 ? -3.771  -7.687  31.227  1.00 30.87  ? 222 SER A OG  1 
ATOM   1747  N  N   . SER A 1 223 ? -4.335  -5.769  33.965  1.00 30.45  ? 223 SER A N   1 
ATOM   1748  C  CA  . SER A 1 223 ? -3.301  -5.305  34.885  1.00 34.11  ? 223 SER A CA  1 
ATOM   1749  C  C   . SER A 1 223 ? -3.893  -4.680  36.155  1.00 28.41  ? 223 SER A C   1 
ATOM   1750  O  O   . SER A 1 223 ? -5.005  -4.152  36.153  1.00 28.16  ? 223 SER A O   1 
ATOM   1751  C  CB  . SER A 1 223 ? -2.398  -4.278  34.194  1.00 29.89  ? 223 SER A CB  1 
ATOM   1752  O  OG  . SER A 1 223 ? -1.622  -4.862  33.174  1.00 31.58  ? 223 SER A OG  1 
ATOM   1753  N  N   . GLY A 1 224 ? -3.128  -4.729  37.242  1.00 31.88  ? 224 GLY A N   1 
ATOM   1754  C  CA  . GLY A 1 224 ? -3.485  -3.997  38.444  1.00 36.06  ? 224 GLY A CA  1 
ATOM   1755  C  C   . GLY A 1 224 ? -4.383  -4.774  39.385  1.00 42.91  ? 224 GLY A C   1 
ATOM   1756  O  O   . GLY A 1 224 ? -4.716  -5.939  39.139  1.00 42.95  ? 224 GLY A O   1 
ATOM   1757  N  N   . PRO A 1 225 ? -4.817  -4.128  40.474  1.00 41.07  ? 225 PRO A N   1 
ATOM   1758  C  CA  . PRO A 1 225 ? -5.538  -4.877  41.516  1.00 47.16  ? 225 PRO A CA  1 
ATOM   1759  C  C   . PRO A 1 225 ? -6.942  -5.264  41.096  1.00 51.64  ? 225 PRO A C   1 
ATOM   1760  O  O   . PRO A 1 225 ? -7.434  -6.336  41.470  1.00 49.71  ? 225 PRO A O   1 
ATOM   1761  C  CB  . PRO A 1 225 ? -5.563  -3.897  42.702  1.00 48.25  ? 225 PRO A CB  1 
ATOM   1762  C  CG  . PRO A 1 225 ? -4.888  -2.611  42.209  1.00 47.24  ? 225 PRO A CG  1 
ATOM   1763  C  CD  . PRO A 1 225 ? -4.862  -2.678  40.721  1.00 44.85  ? 225 PRO A CD  1 
ATOM   1764  N  N   . ASN A 1 226 ? -7.614  -4.397  40.343  1.00 49.54  ? 226 ASN A N   1 
ATOM   1765  C  CA  . ASN A 1 226 ? -8.994  -4.612  39.927  1.00 45.66  ? 226 ASN A CA  1 
ATOM   1766  C  C   . ASN A 1 226 ? -9.051  -5.184  38.517  1.00 48.52  ? 226 ASN A C   1 
ATOM   1767  O  O   . ASN A 1 226 ? -9.909  -4.834  37.699  1.00 50.75  ? 226 ASN A O   1 
ATOM   1768  C  CB  . ASN A 1 226 ? -9.784  -3.311  40.048  1.00 48.00  ? 226 ASN A CB  1 
ATOM   1769  C  CG  . ASN A 1 226 ? -9.620  -2.649  41.423  1.00 54.53  ? 226 ASN A CG  1 
ATOM   1770  O  OD1 . ASN A 1 226 ? -8.513  -2.578  41.965  1.00 56.37  ? 226 ASN A OD1 1 
ATOM   1771  N  ND2 . ASN A 1 226 ? -10.725 -2.172  41.991  1.00 54.14  ? 226 ASN A ND2 1 
ATOM   1772  N  N   . GLY A 1 227 ? -8.123  -6.084  38.221  1.00 41.88  ? 227 GLY A N   1 
ATOM   1773  C  CA  . GLY A 1 227 ? -8.097  -6.708  36.920  1.00 42.02  ? 227 GLY A CA  1 
ATOM   1774  C  C   . GLY A 1 227 ? -9.297  -7.606  36.691  1.00 51.48  ? 227 GLY A C   1 
ATOM   1775  O  O   . GLY A 1 227 ? -9.854  -8.204  37.615  1.00 53.59  ? 227 GLY A O   1 
ATOM   1776  N  N   . ARG A 1 228 ? -9.683  -7.704  35.422  1.00 45.49  ? 228 ARG A N   1 
ATOM   1777  C  CA  . ARG A 1 228 ? -10.877 -8.424  35.014  1.00 40.82  ? 228 ARG A CA  1 
ATOM   1778  C  C   . ARG A 1 228 ? -10.683 -8.845  33.575  1.00 42.45  ? 228 ARG A C   1 
ATOM   1779  O  O   . ARG A 1 228 ? -9.830  -8.311  32.864  1.00 46.23  ? 228 ARG A O   1 
ATOM   1780  C  CB  . ARG A 1 228 ? -12.123 -7.553  35.150  1.00 42.62  ? 228 ARG A CB  1 
ATOM   1781  C  CG  . ARG A 1 228 ? -11.955 -6.200  34.501  1.00 42.75  ? 228 ARG A CG  1 
ATOM   1782  C  CD  . ARG A 1 228 ? -13.140 -5.315  34.747  1.00 42.98  ? 228 ARG A CD  1 
ATOM   1783  N  NE  . ARG A 1 228 ? -13.576 -4.664  33.517  1.00 47.89  ? 228 ARG A NE  1 
ATOM   1784  C  CZ  . ARG A 1 228 ? -13.617 -3.353  33.316  1.00 45.26  ? 228 ARG A CZ  1 
ATOM   1785  N  NH1 . ARG A 1 228 ? -13.171 -2.494  34.225  1.00 44.93  ? 228 ARG A NH1 1 
ATOM   1786  N  NH2 . ARG A 1 228 ? -14.126 -2.891  32.179  1.00 49.39  ? 228 ARG A NH2 1 
ATOM   1787  N  N   . ASP A 1 229 ? -11.462 -9.817  33.154  1.00 41.59  ? 229 ASP A N   1 
ATOM   1788  C  CA  . ASP A 1 229 ? -11.422 -10.210 31.760  1.00 45.26  ? 229 ASP A CA  1 
ATOM   1789  C  C   . ASP A 1 229 ? -12.548 -9.507  31.017  1.00 36.66  ? 229 ASP A C   1 
ATOM   1790  O  O   . ASP A 1 229 ? -13.441 -8.908  31.619  1.00 39.50  ? 229 ASP A O   1 
ATOM   1791  C  CB  . ASP A 1 229 ? -11.505 -11.732 31.622  1.00 52.98  ? 229 ASP A CB  1 
ATOM   1792  C  CG  . ASP A 1 229 ? -10.184 -12.336 31.206  1.00 50.75  ? 229 ASP A CG  1 
ATOM   1793  O  OD1 . ASP A 1 229 ? -9.677  -11.929 30.139  1.00 54.16  ? 229 ASP A OD1 1 
ATOM   1794  O  OD2 . ASP A 1 229 ? -9.648  -13.196 31.942  1.00 56.02  ? 229 ASP A OD2 1 
ATOM   1795  N  N   . MET A 1 230 ? -12.486 -9.557  29.694  1.00 39.59  ? 230 MET A N   1 
ATOM   1796  C  CA  . MET A 1 230 ? -13.450 -8.846  28.870  1.00 35.39  ? 230 MET A CA  1 
ATOM   1797  C  C   . MET A 1 230 ? -14.677 -9.721  28.637  1.00 35.10  ? 230 MET A C   1 
ATOM   1798  O  O   . MET A 1 230 ? -14.549 -10.851 28.153  1.00 32.58  ? 230 MET A O   1 
ATOM   1799  C  CB  . MET A 1 230 ? -12.827 -8.438  27.536  1.00 31.06  ? 230 MET A CB  1 
ATOM   1800  C  CG  . MET A 1 230 ? -13.847 -8.241  26.450  1.00 29.58  ? 230 MET A CG  1 
ATOM   1801  S  SD  . MET A 1 230 ? -13.148 -7.659  24.910  1.00 30.74  ? 230 MET A SD  1 
ATOM   1802  C  CE  . MET A 1 230 ? -12.613 -5.994  25.398  1.00 34.49  ? 230 MET A CE  1 
ATOM   1803  N  N   . THR A 1 231 ? -15.859 -9.188  28.980  1.00 35.10  ? 231 THR A N   1 
ATOM   1804  C  CA  . THR A 1 231 ? -17.104 -9.937  28.874  1.00 33.83  ? 231 THR A CA  1 
ATOM   1805  C  C   . THR A 1 231 ? -17.515 -10.109 27.409  1.00 37.28  ? 231 THR A C   1 
ATOM   1806  O  O   . THR A 1 231 ? -16.981 -9.470  26.490  1.00 29.83  ? 231 THR A O   1 
ATOM   1807  C  CB  . THR A 1 231 ? -18.238 -9.263  29.660  1.00 31.13  ? 231 THR A CB  1 
ATOM   1808  O  OG1 . THR A 1 231 ? -18.785 -8.171  28.928  1.00 29.65  ? 231 THR A OG1 1 
ATOM   1809  C  CG2 . THR A 1 231 ? -17.744 -8.757  30.990  1.00 37.41  ? 231 THR A CG2 1 
ATOM   1810  N  N   . VAL A 1 232 ? -18.471 -11.019 27.203  1.00 32.17  ? 232 VAL A N   1 
ATOM   1811  C  CA  . VAL A 1 232 ? -19.066 -11.192 25.881  1.00 33.73  ? 232 VAL A CA  1 
ATOM   1812  C  C   . VAL A 1 232 ? -19.718 -9.898  25.411  1.00 30.55  ? 232 VAL A C   1 
ATOM   1813  O  O   . VAL A 1 232 ? -19.582 -9.497  24.252  1.00 29.43  ? 232 VAL A O   1 
ATOM   1814  C  CB  . VAL A 1 232 ? -20.078 -12.350 25.909  1.00 31.59  ? 232 VAL A CB  1 
ATOM   1815  C  CG1 . VAL A 1 232 ? -20.949 -12.323 24.658  1.00 33.38  ? 232 VAL A CG1 1 
ATOM   1816  C  CG2 . VAL A 1 232 ? -19.332 -13.667 26.019  1.00 33.19  ? 232 VAL A CG2 1 
ATOM   1817  N  N   . GLU A 1 233 ? -20.439 -9.233  26.300  1.00 27.62  ? 233 GLU A N   1 
ATOM   1818  C  CA  . GLU A 1 233 ? -21.167 -8.048  25.899  1.00 30.54  ? 233 GLU A CA  1 
ATOM   1819  C  C   . GLU A 1 233 ? -20.213 -6.925  25.520  1.00 30.73  ? 233 GLU A C   1 
ATOM   1820  O  O   . GLU A 1 233 ? -20.480 -6.171  24.581  1.00 29.27  ? 233 GLU A O   1 
ATOM   1821  C  CB  . GLU A 1 233 ? -22.100 -7.632  27.029  1.00 31.54  ? 233 GLU A CB  1 
ATOM   1822  C  CG  . GLU A 1 233 ? -23.296 -8.571  27.241  1.00 38.21  ? 233 GLU A CG  1 
ATOM   1823  C  CD  . GLU A 1 233 ? -22.953 -9.883  27.959  1.00 40.42  ? 233 GLU A CD  1 
ATOM   1824  O  OE1 . GLU A 1 233 ? -22.120 -9.863  28.907  1.00 33.73  ? 233 GLU A OE1 1 
ATOM   1825  O  OE2 . GLU A 1 233 ? -23.535 -10.929 27.560  1.00 35.52  ? 233 GLU A OE2 1 
ATOM   1826  N  N   . GLU A 1 234 ? -19.083 -6.830  26.215  1.00 28.35  ? 234 GLU A N   1 
ATOM   1827  C  CA  . GLU A 1 234 ? -18.089 -5.825  25.874  1.00 31.37  ? 234 GLU A CA  1 
ATOM   1828  C  C   . GLU A 1 234 ? -17.396 -6.171  24.562  1.00 30.29  ? 234 GLU A C   1 
ATOM   1829  O  O   . GLU A 1 234 ? -17.185 -5.292  23.722  1.00 27.97  ? 234 GLU A O   1 
ATOM   1830  C  CB  . GLU A 1 234 ? -17.093 -5.698  27.020  1.00 30.68  ? 234 GLU A CB  1 
ATOM   1831  C  CG  . GLU A 1 234 ? -17.726 -5.146  28.313  1.00 32.95  ? 234 GLU A CG  1 
ATOM   1832  C  CD  . GLU A 1 234 ? -16.940 -5.528  29.552  1.00 35.72  ? 234 GLU A CD  1 
ATOM   1833  O  OE1 . GLU A 1 234 ? -15.981 -6.330  29.418  1.00 34.99  ? 234 GLU A OE1 1 
ATOM   1834  O  OE2 . GLU A 1 234 ? -17.271 -5.019  30.650  1.00 43.11  ? 234 GLU A OE2 1 
ATOM   1835  N  N   . GLY A 1 235 ? -17.083 -7.459  24.350  1.00 28.92  ? 235 GLY A N   1 
ATOM   1836  C  CA  . GLY A 1 235 ? -16.498 -7.884  23.084  1.00 24.45  ? 235 GLY A CA  1 
ATOM   1837  C  C   . GLY A 1 235 ? -17.348 -7.522  21.878  1.00 27.23  ? 235 GLY A C   1 
ATOM   1838  O  O   . GLY A 1 235 ? -16.840 -6.995  20.887  1.00 28.73  ? 235 GLY A O   1 
ATOM   1839  N  N   . ALA A 1 236 ? -18.654 -7.789  21.947  1.00 29.66  ? 236 ALA A N   1 
ATOM   1840  C  CA  . ALA A 1 236 ? -19.531 -7.512  20.809  1.00 31.61  ? 236 ALA A CA  1 
ATOM   1841  C  C   . ALA A 1 236 ? -19.860 -6.032  20.676  1.00 28.40  ? 236 ALA A C   1 
ATOM   1842  O  O   . ALA A 1 236 ? -20.048 -5.541  19.558  1.00 29.74  ? 236 ALA A O   1 
ATOM   1843  C  CB  . ALA A 1 236 ? -20.830 -8.315  20.928  1.00 31.54  ? 236 ALA A CB  1 
ATOM   1844  N  N   . ALA A 1 237 ? -19.970 -5.319  21.796  1.00 27.12  ? 237 ALA A N   1 
ATOM   1845  C  CA  . ALA A 1 237 ? -20.229 -3.892  21.726  1.00 25.89  ? 237 ALA A CA  1 
ATOM   1846  C  C   . ALA A 1 237 ? -19.088 -3.182  21.002  1.00 30.40  ? 237 ALA A C   1 
ATOM   1847  O  O   . ALA A 1 237 ? -19.325 -2.265  20.209  1.00 33.53  ? 237 ALA A O   1 
ATOM   1848  C  CB  . ALA A 1 237 ? -20.443 -3.340  23.137  1.00 25.67  ? 237 ALA A CB  1 
ATOM   1849  N  N   . ALA A 1 238 ? -17.845 -3.634  21.230  1.00 30.12  ? 238 ALA A N   1 
ATOM   1850  C  CA  . ALA A 1 238 ? -16.683 -3.141  20.492  1.00 30.46  ? 238 ALA A CA  1 
ATOM   1851  C  C   . ALA A 1 238 ? -16.689 -3.601  19.031  1.00 32.29  ? 238 ALA A C   1 
ATOM   1852  O  O   . ALA A 1 238 ? -16.443 -2.800  18.114  1.00 24.15  ? 238 ALA A O   1 
ATOM   1853  C  CB  . ALA A 1 238 ? -15.407 -3.612  21.184  1.00 30.34  ? 238 ALA A CB  1 
ATOM   1854  N  N   . LEU A 1 239 ? -16.938 -4.899  18.787  1.00 29.86  ? 239 LEU A N   1 
ATOM   1855  C  CA  . LEU A 1 239 ? -17.013 -5.362  17.397  1.00 27.54  ? 239 LEU A CA  1 
ATOM   1856  C  C   . LEU A 1 239 ? -18.119 -4.641  16.637  1.00 30.01  ? 239 LEU A C   1 
ATOM   1857  O  O   . LEU A 1 239 ? -17.943 -4.265  15.469  1.00 31.49  ? 239 LEU A O   1 
ATOM   1858  C  CB  . LEU A 1 239 ? -17.236 -6.870  17.328  1.00 29.24  ? 239 LEU A CB  1 
ATOM   1859  C  CG  . LEU A 1 239 ? -17.333 -7.386  15.886  1.00 34.57  ? 239 LEU A CG  1 
ATOM   1860  C  CD1 . LEU A 1 239 ? -16.194 -6.848  15.038  1.00 28.35  ? 239 LEU A CD1 1 
ATOM   1861  C  CD2 . LEU A 1 239 ? -17.327 -8.897  15.828  1.00 30.59  ? 239 LEU A CD2 1 
ATOM   1862  N  N   . GLN A 1 240 ? -19.270 -4.444  17.276  1.00 28.73  ? 240 GLN A N   1 
ATOM   1863  C  CA  . GLN A 1 240 ? -20.339 -3.719  16.607  1.00 30.18  ? 240 GLN A CA  1 
ATOM   1864  C  C   . GLN A 1 240 ? -19.922 -2.283  16.348  1.00 27.28  ? 240 GLN A C   1 
ATOM   1865  O  O   . GLN A 1 240 ? -20.291 -1.712  15.322  1.00 23.18  ? 240 GLN A O   1 
ATOM   1866  C  CB  . GLN A 1 240 ? -21.638 -3.765  17.427  1.00 26.04  ? 240 GLN A CB  1 
ATOM   1867  C  CG  . GLN A 1 240 ? -22.377 -5.117  17.396  1.00 31.69  ? 240 GLN A CG  1 
ATOM   1868  C  CD  . GLN A 1 240 ? -23.289 -5.342  18.601  1.00 36.26  ? 240 GLN A CD  1 
ATOM   1869  O  OE1 . GLN A 1 240 ? -23.838 -4.391  19.173  1.00 46.65  ? 240 GLN A OE1 1 
ATOM   1870  N  NE2 . GLN A 1 240 ? -23.451 -6.602  18.994  1.00 36.05  ? 240 GLN A NE2 1 
ATOM   1871  N  N   . ARG A 1 241 ? -19.147 -1.692  17.261  1.00 33.55  ? 241 ARG A N   1 
ATOM   1872  C  CA  . ARG A 1 241 ? -18.714 -0.309  17.073  1.00 31.89  ? 241 ARG A CA  1 
ATOM   1873  C  C   . ARG A 1 241 ? -17.825 -0.189  15.845  1.00 26.15  ? 241 ARG A C   1 
ATOM   1874  O  O   . ARG A 1 241 ? -17.925 0.785   15.096  1.00 31.13  ? 241 ARG A O   1 
ATOM   1875  C  CB  . ARG A 1 241 ? -18.010 0.198   18.340  1.00 29.45  ? 241 ARG A CB  1 
ATOM   1876  C  CG  . ARG A 1 241 ? -16.779 1.099   18.119  1.00 33.84  ? 241 ARG A CG  1 
ATOM   1877  C  CD  . ARG A 1 241 ? -15.748 0.978   19.272  1.00 34.84  ? 241 ARG A CD  1 
ATOM   1878  N  NE  . ARG A 1 241 ? -14.800 -0.128  19.113  1.00 34.53  ? 241 ARG A NE  1 
ATOM   1879  C  CZ  . ARG A 1 241 ? -13.830 -0.424  19.976  1.00 41.08  ? 241 ARG A CZ  1 
ATOM   1880  N  NH1 . ARG A 1 241 ? -13.725 0.193   21.148  1.00 39.67  ? 241 ARG A NH1 1 
ATOM   1881  N  NH2 . ARG A 1 241 ? -12.939 -1.360  19.655  1.00 38.26  ? 241 ARG A NH2 1 
ATOM   1882  N  N   . ASP A 1 242 ? -16.979 -1.194  15.596  1.00 28.08  ? 242 ASP A N   1 
ATOM   1883  C  CA  . ASP A 1 242 ? -16.095 -1.168  14.432  1.00 33.01  ? 242 ASP A CA  1 
ATOM   1884  C  C   . ASP A 1 242 ? -16.790 -1.595  13.145  1.00 25.67  ? 242 ASP A C   1 
ATOM   1885  O  O   . ASP A 1 242 ? -16.354 -1.201  12.067  1.00 25.61  ? 242 ASP A O   1 
ATOM   1886  C  CB  . ASP A 1 242 ? -14.852 -2.049  14.665  1.00 33.95  ? 242 ASP A CB  1 
ATOM   1887  C  CG  . ASP A 1 242 ? -13.920 -1.485  15.751  1.00 32.31  ? 242 ASP A CG  1 
ATOM   1888  O  OD1 . ASP A 1 242 ? -13.747 -0.257  15.833  1.00 28.94  ? 242 ASP A OD1 1 
ATOM   1889  O  OD2 . ASP A 1 242 ? -13.386 -2.271  16.558  1.00 34.03  ? 242 ASP A OD2 1 
ATOM   1890  N  N   . LEU A 1 243 ? -17.864 -2.373  13.221  1.00 24.72  ? 243 LEU A N   1 
ATOM   1891  C  CA  . LEU A 1 243 ? -18.636 -2.640  12.013  1.00 30.40  ? 243 LEU A CA  1 
ATOM   1892  C  C   . LEU A 1 243 ? -19.323 -1.378  11.512  1.00 26.63  ? 243 LEU A C   1 
ATOM   1893  O  O   . LEU A 1 243 ? -19.366 -1.135  10.306  1.00 28.75  ? 243 LEU A O   1 
ATOM   1894  C  CB  . LEU A 1 243 ? -19.667 -3.744  12.265  1.00 33.67  ? 243 LEU A CB  1 
ATOM   1895  C  CG  . LEU A 1 243 ? -19.048 -5.122  12.470  1.00 28.09  ? 243 LEU A CG  1 
ATOM   1896  C  CD1 . LEU A 1 243 ? -20.060 -6.073  13.144  1.00 28.09  ? 243 LEU A CD1 1 
ATOM   1897  C  CD2 . LEU A 1 243 ? -18.578 -5.666  11.133  1.00 29.30  ? 243 LEU A CD2 1 
ATOM   1898  N  N   . ARG A 1 244 ? -19.854 -0.558  12.423  1.00 28.88  ? 244 ARG A N   1 
ATOM   1899  C  CA  . ARG A 1 244 ? -20.546 0.665   12.020  1.00 23.49  ? 244 ARG A CA  1 
ATOM   1900  C  C   . ARG A 1 244 ? -19.563 1.701   11.485  1.00 29.52  ? 244 ARG A C   1 
ATOM   1901  O  O   . ARG A 1 244 ? -19.817 2.343   10.456  1.00 26.39  ? 244 ARG A O   1 
ATOM   1902  C  CB  . ARG A 1 244 ? -21.333 1.233   13.200  1.00 26.59  ? 244 ARG A CB  1 
ATOM   1903  C  CG  . ARG A 1 244 ? -22.422 0.287   13.728  1.00 34.47  ? 244 ARG A CG  1 
ATOM   1904  C  CD  . ARG A 1 244 ? -23.476 1.036   14.506  1.00 31.75  ? 244 ARG A CD  1 
ATOM   1905  N  NE  . ARG A 1 244 ? -24.252 0.176   15.395  1.00 34.88  ? 244 ARG A NE  1 
ATOM   1906  C  CZ  . ARG A 1 244 ? -23.837 -0.227  16.591  1.00 43.21  ? 244 ARG A CZ  1 
ATOM   1907  N  NH1 . ARG A 1 244 ? -22.640 0.110   17.058  1.00 41.46  ? 244 ARG A NH1 1 
ATOM   1908  N  NH2 . ARG A 1 244 ? -24.641 -0.986  17.340  1.00 36.41  ? 244 ARG A NH2 1 
ATOM   1909  N  N   . LEU A 1 245 ? -18.448 1.900   12.199  1.00 29.00  ? 245 LEU A N   1 
ATOM   1910  C  CA  . LEU A 1 245 ? -17.380 2.749   11.687  1.00 27.22  ? 245 LEU A CA  1 
ATOM   1911  C  C   . LEU A 1 245 ? -16.985 2.322   10.278  1.00 25.70  ? 245 LEU A C   1 
ATOM   1912  O  O   . LEU A 1 245 ? -16.898 3.146   9.362   1.00 26.63  ? 245 LEU A O   1 
ATOM   1913  C  CB  . LEU A 1 245 ? -16.158 2.693   12.617  1.00 21.88  ? 245 LEU A CB  1 
ATOM   1914  C  CG  . LEU A 1 245 ? -15.036 3.608   12.084  1.00 24.54  ? 245 LEU A CG  1 
ATOM   1915  C  CD1 . LEU A 1 245 ? -15.526 5.060   11.934  1.00 23.25  ? 245 LEU A CD1 1 
ATOM   1916  C  CD2 . LEU A 1 245 ? -13.798 3.545   12.949  1.00 25.40  ? 245 LEU A CD2 1 
ATOM   1917  N  N   . ALA A 1 246 ? -16.716 1.028   10.097  1.00 23.48  ? 246 ALA A N   1 
ATOM   1918  C  CA  . ALA A 1 246 ? -16.383 0.507   8.775   1.00 21.47  ? 246 ALA A CA  1 
ATOM   1919  C  C   . ALA A 1 246 ? -17.423 0.888   7.734   1.00 24.90  ? 246 ALA A C   1 
ATOM   1920  O  O   . ALA A 1 246 ? -17.087 1.439   6.677   1.00 24.68  ? 246 ALA A O   1 
ATOM   1921  C  CB  . ALA A 1 246 ? -16.253 -1.008  8.831   1.00 24.59  ? 246 ALA A CB  1 
ATOM   1922  N  N   . LYS A 1 247 ? -18.686 0.539   7.984   1.00 25.50  ? 247 LYS A N   1 
ATOM   1923  C  CA  . LYS A 1 247 ? -19.757 0.899   7.055   1.00 25.02  ? 247 LYS A CA  1 
ATOM   1924  C  C   . LYS A 1 247 ? -19.755 2.386   6.749   1.00 25.38  ? 247 LYS A C   1 
ATOM   1925  O  O   . LYS A 1 247 ? -19.794 2.787   5.584   1.00 25.30  ? 247 LYS A O   1 
ATOM   1926  C  CB  . LYS A 1 247 ? -21.118 0.507   7.627   1.00 27.35  ? 247 LYS A CB  1 
ATOM   1927  C  CG  . LYS A 1 247 ? -22.262 0.728   6.642   1.00 28.27  ? 247 LYS A CG  1 
ATOM   1928  C  CD  . LYS A 1 247 ? -21.872 0.245   5.249   1.00 28.81  ? 247 LYS A CD  1 
ATOM   1929  C  CE  . LYS A 1 247 ? -23.026 0.386   4.251   1.00 31.66  ? 247 LYS A CE  1 
ATOM   1930  N  NZ  . LYS A 1 247 ? -24.317 0.100   4.952   1.00 32.89  ? 247 LYS A NZ  1 
ATOM   1931  N  N   . ARG A 1 248 ? -19.767 3.215   7.797   1.00 27.34  ? 248 ARG A N   1 
ATOM   1932  C  CA  . ARG A 1 248 ? -19.741 4.668   7.627   1.00 24.47  ? 248 ARG A CA  1 
ATOM   1933  C  C   . ARG A 1 248 ? -18.628 5.127   6.690   1.00 24.76  ? 248 ARG A C   1 
ATOM   1934  O  O   . ARG A 1 248 ? -18.843 5.996   5.838   1.00 28.72  ? 248 ARG A O   1 
ATOM   1935  C  CB  . ARG A 1 248 ? -19.599 5.334   8.992   1.00 24.53  ? 248 ARG A CB  1 
ATOM   1936  C  CG  . ARG A 1 248 ? -19.317 6.799   8.904   1.00 30.70  ? 248 ARG A CG  1 
ATOM   1937  C  CD  . ARG A 1 248 ? -19.180 7.423   10.268  1.00 31.87  ? 248 ARG A CD  1 
ATOM   1938  N  NE  . ARG A 1 248 ? -19.529 8.836   10.196  1.00 32.38  ? 248 ARG A NE  1 
ATOM   1939  C  CZ  . ARG A 1 248 ? -19.087 9.764   11.036  1.00 40.10  ? 248 ARG A CZ  1 
ATOM   1940  N  NH1 . ARG A 1 248 ? -18.299 9.458   12.055  1.00 37.60  ? 248 ARG A NH1 1 
ATOM   1941  N  NH2 . ARG A 1 248 ? -19.444 11.032  10.846  1.00 42.02  ? 248 ARG A NH2 1 
ATOM   1942  N  N   . LEU A 1 249 ? -17.432 4.562   6.823   1.00 25.62  ? 249 LEU A N   1 
ATOM   1943  C  CA  . LEU A 1 249 ? -16.323 4.912   5.937   1.00 22.13  ? 249 LEU A CA  1 
ATOM   1944  C  C   . LEU A 1 249 ? -16.299 4.101   4.640   1.00 26.24  ? 249 LEU A C   1 
ATOM   1945  O  O   . LEU A 1 249 ? -15.364 4.257   3.841   1.00 18.77  ? 249 LEU A O   1 
ATOM   1946  C  CB  . LEU A 1 249 ? -14.989 4.745   6.680   1.00 19.45  ? 249 LEU A CB  1 
ATOM   1947  C  CG  . LEU A 1 249 ? -14.919 5.577   7.976   1.00 22.62  ? 249 LEU A CG  1 
ATOM   1948  C  CD1 . LEU A 1 249 ? -13.576 5.382   8.700   1.00 22.89  ? 249 LEU A CD1 1 
ATOM   1949  C  CD2 . LEU A 1 249 ? -15.124 6.997   7.592   1.00 19.72  ? 249 LEU A CD2 1 
ATOM   1950  N  N   . GLY A 1 250 ? -17.274 3.228   4.419   1.00 20.44  ? 250 GLY A N   1 
ATOM   1951  C  CA  . GLY A 1 250 ? -17.416 2.608   3.109   1.00 25.60  ? 250 GLY A CA  1 
ATOM   1952  C  C   . GLY A 1 250 ? -16.662 1.314   2.922   1.00 25.49  ? 250 GLY A C   1 
ATOM   1953  O  O   . GLY A 1 250 ? -16.446 0.903   1.774   1.00 23.42  ? 250 GLY A O   1 
ATOM   1954  N  N   . PHE A 1 251 ? -16.248 0.666   4.009   1.00 24.06  ? 251 PHE A N   1 
ATOM   1955  C  CA  . PHE A 1 251 ? -15.536 -0.598  3.935   1.00 27.87  ? 251 PHE A CA  1 
ATOM   1956  C  C   . PHE A 1 251 ? -16.524 -1.740  3.769   1.00 27.53  ? 251 PHE A C   1 
ATOM   1957  O  O   . PHE A 1 251 ? -17.644 -1.710  4.292   1.00 25.33  ? 251 PHE A O   1 
ATOM   1958  C  CB  . PHE A 1 251 ? -14.675 -0.829  5.186   1.00 24.72  ? 251 PHE A CB  1 
ATOM   1959  C  CG  . PHE A 1 251 ? -13.444 0.058   5.229   1.00 26.70  ? 251 PHE A CG  1 
ATOM   1960  C  CD1 . PHE A 1 251 ? -12.274 -0.331  4.610   1.00 22.19  ? 251 PHE A CD1 1 
ATOM   1961  C  CD2 . PHE A 1 251 ? -13.486 1.308   5.841   1.00 24.68  ? 251 PHE A CD2 1 
ATOM   1962  C  CE1 . PHE A 1 251 ? -11.146 0.519   4.607   1.00 28.47  ? 251 PHE A CE1 1 
ATOM   1963  C  CE2 . PHE A 1 251 ? -12.372 2.142   5.845   1.00 21.70  ? 251 PHE A CE2 1 
ATOM   1964  C  CZ  . PHE A 1 251 ? -11.208 1.753   5.237   1.00 18.85  ? 251 PHE A CZ  1 
ATOM   1965  N  N   . ARG A 1 252 ? -16.091 -2.744  3.008   1.00 24.19  ? 252 ARG A N   1 
ATOM   1966  C  CA  . ARG A 1 252 ? -16.815 -3.988  2.848   1.00 27.13  ? 252 ARG A CA  1 
ATOM   1967  C  C   . ARG A 1 252 ? -16.401 -5.053  3.865   1.00 32.55  ? 252 ARG A C   1 
ATOM   1968  O  O   . ARG A 1 252 ? -17.245 -5.863  4.276   1.00 35.39  ? 252 ARG A O   1 
ATOM   1969  C  CB  . ARG A 1 252 ? -16.616 -4.495  1.414   1.00 31.71  ? 252 ARG A CB  1 
ATOM   1970  C  CG  . ARG A 1 252 ? -17.402 -3.666  0.365   1.00 36.06  ? 252 ARG A CG  1 
ATOM   1971  C  CD  . ARG A 1 252 ? -16.831 -3.777  -1.057  1.00 34.54  ? 252 ARG A CD  1 
ATOM   1972  N  NE  . ARG A 1 252 ? -16.312 -5.111  -1.330  1.00 37.68  ? 252 ARG A NE  1 
ATOM   1973  C  CZ  . ARG A 1 252 ? -15.208 -5.360  -2.019  1.00 45.30  ? 252 ARG A CZ  1 
ATOM   1974  N  NH1 . ARG A 1 252 ? -14.479 -4.381  -2.543  1.00 47.85  ? 252 ARG A NH1 1 
ATOM   1975  N  NH2 . ARG A 1 252 ? -14.827 -6.623  -2.195  1.00 48.25  ? 252 ARG A NH2 1 
ATOM   1976  N  N   . PHE A 1 253 ? -15.137 -5.074  4.306   1.00 26.19  ? 253 PHE A N   1 
ATOM   1977  C  CA  . PHE A 1 253 ? -14.671 -6.079  5.257   1.00 28.51  ? 253 PHE A CA  1 
ATOM   1978  C  C   . PHE A 1 253 ? -14.178 -5.440  6.550   1.00 30.58  ? 253 PHE A C   1 
ATOM   1979  O  O   . PHE A 1 253 ? -13.593 -4.351  6.540   1.00 31.39  ? 253 PHE A O   1 
ATOM   1980  C  CB  . PHE A 1 253 ? -13.533 -6.905  4.684   1.00 27.70  ? 253 PHE A CB  1 
ATOM   1981  C  CG  . PHE A 1 253 ? -13.806 -7.447  3.315   1.00 33.81  ? 253 PHE A CG  1 
ATOM   1982  C  CD1 . PHE A 1 253 ? -14.644 -8.540  3.132   1.00 34.51  ? 253 PHE A CD1 1 
ATOM   1983  C  CD2 . PHE A 1 253 ? -13.233 -6.860  2.208   1.00 28.65  ? 253 PHE A CD2 1 
ATOM   1984  C  CE1 . PHE A 1 253 ? -14.892 -9.037  1.860   1.00 32.27  ? 253 PHE A CE1 1 
ATOM   1985  C  CE2 . PHE A 1 253 ? -13.469 -7.351  0.938   1.00 30.98  ? 253 PHE A CE2 1 
ATOM   1986  C  CZ  . PHE A 1 253 ? -14.299 -8.436  0.765   1.00 34.09  ? 253 PHE A CZ  1 
ATOM   1987  N  N   . VAL A 1 254 ? -14.387 -6.150  7.660   1.00 21.71  ? 254 VAL A N   1 
ATOM   1988  C  CA  . VAL A 1 254 ? -13.754 -5.840  8.942   1.00 29.58  ? 254 VAL A CA  1 
ATOM   1989  C  C   . VAL A 1 254 ? -13.053 -7.082  9.469   1.00 28.54  ? 254 VAL A C   1 
ATOM   1990  O  O   . VAL A 1 254 ? -13.692 -8.126  9.649   1.00 33.73  ? 254 VAL A O   1 
ATOM   1991  C  CB  . VAL A 1 254 ? -14.763 -5.343  9.992   1.00 24.64  ? 254 VAL A CB  1 
ATOM   1992  C  CG1 . VAL A 1 254 ? -14.072 -5.157  11.323  1.00 28.31  ? 254 VAL A CG1 1 
ATOM   1993  C  CG2 . VAL A 1 254 ? -15.356 -4.061  9.550   1.00 26.19  ? 254 VAL A CG2 1 
ATOM   1994  N  N   . ARG A 1 255 ? -11.759 -6.952  9.782   1.00 29.38  ? 255 ARG A N   1 
ATOM   1995  C  CA  . ARG A 1 255 ? -10.996 -8.025  10.409  1.00 25.12  ? 255 ARG A CA  1 
ATOM   1996  C  C   . ARG A 1 255 ? -10.804 -7.757  11.897  1.00 31.21  ? 255 ARG A C   1 
ATOM   1997  O  O   . ARG A 1 255 ? -9.864  -7.035  12.270  1.00 34.67  ? 255 ARG A O   1 
ATOM   1998  C  CB  . ARG A 1 255 ? -9.641  -8.178  9.727   1.00 26.94  ? 255 ARG A CB  1 
ATOM   1999  C  CG  . ARG A 1 255 ? -8.764  -9.250  10.324  1.00 29.46  ? 255 ARG A CG  1 
ATOM   2000  C  CD  . ARG A 1 255 ? -7.364  -8.708  10.539  1.00 29.35  ? 255 ARG A CD  1 
ATOM   2001  N  NE  . ARG A 1 255 ? -7.325  -7.682  11.578  1.00 34.01  ? 255 ARG A NE  1 
ATOM   2002  C  CZ  . ARG A 1 255 ? -6.205  -7.220  12.127  1.00 37.99  ? 255 ARG A CZ  1 
ATOM   2003  N  NH1 . ARG A 1 255 ? -5.017  -7.693  11.772  1.00 38.58  ? 255 ARG A NH1 1 
ATOM   2004  N  NH2 . ARG A 1 255 ? -6.279  -6.270  13.060  1.00 28.45  ? 255 ARG A NH2 1 
ATOM   2005  N  N   . PRO A 1 256 ? -11.608 -8.348  12.787  1.00 29.71  ? 256 PRO A N   1 
ATOM   2006  C  CA  . PRO A 1 256 ? -11.316 -8.255  14.229  1.00 31.47  ? 256 PRO A CA  1 
ATOM   2007  C  C   . PRO A 1 256 ? -10.163 -9.180  14.587  1.00 33.47  ? 256 PRO A C   1 
ATOM   2008  O  O   . PRO A 1 256 ? -10.226 -10.391 14.359  1.00 34.78  ? 256 PRO A O   1 
ATOM   2009  C  CB  . PRO A 1 256 ? -12.624 -8.705  14.891  1.00 30.19  ? 256 PRO A CB  1 
ATOM   2010  C  CG  . PRO A 1 256 ? -13.258 -9.626  13.904  1.00 28.32  ? 256 PRO A CG  1 
ATOM   2011  C  CD  . PRO A 1 256 ? -12.700 -9.305  12.509  1.00 30.11  ? 256 PRO A CD  1 
ATOM   2012  N  N   . LYS A 1 257 ? -9.094  -8.605  15.121  1.00 30.49  ? 257 LYS A N   1 
ATOM   2013  C  CA  . LYS A 1 257 ? -8.011  -9.395  15.686  1.00 29.24  ? 257 LYS A CA  1 
ATOM   2014  C  C   . LYS A 1 257 ? -8.352  -9.637  17.150  1.00 29.34  ? 257 LYS A C   1 
ATOM   2015  O  O   . LYS A 1 257 ? -8.492  -8.679  17.921  1.00 28.50  ? 257 LYS A O   1 
ATOM   2016  C  CB  . LYS A 1 257 ? -6.670  -8.675  15.517  1.00 32.87  ? 257 LYS A CB  1 
ATOM   2017  C  CG  . LYS A 1 257 ? -5.525  -9.300  16.321  1.00 34.02  ? 257 LYS A CG  1 
ATOM   2018  C  CD  . LYS A 1 257 ? -4.935  -10.533 15.657  1.00 31.53  ? 257 LYS A CD  1 
ATOM   2019  C  CE  . LYS A 1 257 ? -4.816  -10.355 14.168  1.00 29.22  ? 257 LYS A CE  1 
ATOM   2020  N  NZ  . LYS A 1 257 ? -3.700  -9.420  13.904  1.00 42.66  ? 257 LYS A NZ  1 
ATOM   2021  N  N   . ILE A 1 258 ? -8.519  -10.911 17.530  1.00 30.37  ? 258 ILE A N   1 
ATOM   2022  C  CA  . ILE A 1 258 ? -9.017  -11.286 18.856  1.00 31.25  ? 258 ILE A CA  1 
ATOM   2023  C  C   . ILE A 1 258 ? -7.855  -11.654 19.764  1.00 25.22  ? 258 ILE A C   1 
ATOM   2024  O  O   . ILE A 1 258 ? -6.892  -12.296 19.332  1.00 30.55  ? 258 ILE A O   1 
ATOM   2025  C  CB  . ILE A 1 258 ? -10.005 -12.462 18.770  1.00 34.72  ? 258 ILE A CB  1 
ATOM   2026  C  CG1 . ILE A 1 258 ? -11.010 -12.246 17.631  1.00 38.79  ? 258 ILE A CG1 1 
ATOM   2027  C  CG2 . ILE A 1 258 ? -10.705 -12.666 20.100  1.00 28.84  ? 258 ILE A CG2 1 
ATOM   2028  C  CD1 . ILE A 1 258 ? -10.895 -13.303 16.529  1.00 41.89  ? 258 ILE A CD1 1 
ATOM   2029  N  N   . GLY A 1 259 ? -7.947  -11.255 21.026  1.00 25.79  ? 259 GLY A N   1 
ATOM   2030  C  CA  . GLY A 1 259 ? -6.945  -11.666 21.996  1.00 37.48  ? 259 GLY A CA  1 
ATOM   2031  C  C   . GLY A 1 259 ? -6.830  -13.177 22.089  1.00 36.32  ? 259 GLY A C   1 
ATOM   2032  O  O   . GLY A 1 259 ? -7.800  -13.904 21.906  1.00 37.12  ? 259 GLY A O   1 
ATOM   2033  N  N   . VAL A 1 260 ? -5.621  -13.650 22.375  1.00 38.49  ? 260 VAL A N   1 
ATOM   2034  C  CA  . VAL A 1 260 ? -5.303  -15.070 22.303  1.00 41.33  ? 260 VAL A CA  1 
ATOM   2035  C  C   . VAL A 1 260 ? -5.026  -15.632 23.693  1.00 44.92  ? 260 VAL A C   1 
ATOM   2036  O  O   . VAL A 1 260 ? -4.848  -14.902 24.665  1.00 48.76  ? 260 VAL A O   1 
ATOM   2037  C  CB  . VAL A 1 260 ? -4.112  -15.332 21.379  1.00 43.77  ? 260 VAL A CB  1 
ATOM   2038  C  CG1 . VAL A 1 260 ? -4.323  -14.601 20.063  1.00 40.43  ? 260 VAL A CG1 1 
ATOM   2039  C  CG2 . VAL A 1 260 ? -2.840  -14.884 22.077  1.00 40.97  ? 260 VAL A CG2 1 
ATOM   2040  N  N   . VAL A 1 261 ? -4.983  -16.966 23.774  1.00 48.60  ? 261 VAL A N   1 
ATOM   2041  C  CA  . VAL A 1 261 ? -4.779  -17.667 25.035  1.00 49.41  ? 261 VAL A CA  1 
ATOM   2042  C  C   . VAL A 1 261 ? -3.682  -18.724 24.969  1.00 51.02  ? 261 VAL A C   1 
ATOM   2043  O  O   . VAL A 1 261 ? -3.409  -19.375 25.979  1.00 53.40  ? 261 VAL A O   1 
ATOM   2044  C  CB  . VAL A 1 261 ? -6.097  -18.300 25.525  1.00 47.71  ? 261 VAL A CB  1 
ATOM   2045  C  CG1 . VAL A 1 261 ? -7.236  -17.335 25.361  1.00 45.43  ? 261 VAL A CG1 1 
ATOM   2046  C  CG2 . VAL A 1 261 ? -6.392  -19.548 24.727  1.00 54.51  ? 261 VAL A CG2 1 
ATOM   2047  N  N   . SER A 1 262 ? -3.029  -18.909 23.822  1.00 53.65  ? 262 SER A N   1 
ATOM   2048  C  CA  . SER A 1 262 ? -2.084  -20.006 23.646  1.00 57.78  ? 262 SER A CA  1 
ATOM   2049  C  C   . SER A 1 262 ? -1.110  -19.657 22.529  1.00 58.20  ? 262 SER A C   1 
ATOM   2050  O  O   . SER A 1 262 ? -1.303  -18.687 21.788  1.00 55.80  ? 262 SER A O   1 
ATOM   2051  C  CB  . SER A 1 262 ? -2.804  -21.311 23.319  1.00 49.16  ? 262 SER A CB  1 
ATOM   2052  O  OG  . SER A 1 262 ? -3.312  -21.235 21.999  1.00 56.21  ? 262 SER A OG  1 
ATOM   2053  N  N   . SER A 1 263 ? -0.084  -20.506 22.384  1.00 60.05  ? 263 SER A N   1 
ATOM   2054  C  CA  . SER A 1 263 ? 1.067   -20.184 21.540  1.00 57.56  ? 263 SER A CA  1 
ATOM   2055  C  C   . SER A 1 263 ? 0.683   -20.079 20.072  1.00 56.69  ? 263 SER A C   1 
ATOM   2056  O  O   . SER A 1 263 ? 1.102   -19.142 19.377  1.00 58.08  ? 263 SER A O   1 
ATOM   2057  C  CB  . SER A 1 263 ? 2.154   -21.240 21.714  1.00 56.72  ? 263 SER A CB  1 
ATOM   2058  O  OG  . SER A 1 263 ? 2.189   -21.706 23.044  1.00 58.10  ? 263 SER A OG  1 
ATOM   2059  N  N   . ASP A 1 264 ? -0.086  -21.049 19.569  1.00 59.83  ? 264 ASP A N   1 
ATOM   2060  C  CA  . ASP A 1 264 ? -0.511  -21.007 18.175  1.00 54.91  ? 264 ASP A CA  1 
ATOM   2061  C  C   . ASP A 1 264 ? -1.818  -20.230 18.064  1.00 57.57  ? 264 ASP A C   1 
ATOM   2062  O  O   . ASP A 1 264 ? -2.622  -20.462 17.153  1.00 56.93  ? 264 ASP A O   1 
ATOM   2063  C  CB  . ASP A 1 264 ? -0.639  -22.417 17.575  1.00 58.29  ? 264 ASP A CB  1 
ATOM   2064  C  CG  . ASP A 1 264 ? -1.358  -23.403 18.492  1.00 56.72  ? 264 ASP A CG  1 
ATOM   2065  O  OD1 . ASP A 1 264 ? -1.799  -23.013 19.603  1.00 59.76  ? 264 ASP A OD1 1 
ATOM   2066  O  OD2 . ASP A 1 264 ? -1.495  -24.576 18.080  1.00 48.79  ? 264 ASP A OD2 1 
ATOM   2067  N  N   . LEU A 1 265 ? -2.027  -19.305 19.009  1.00 58.34  ? 265 LEU A N   1 
ATOM   2068  C  CA  . LEU A 1 265 ? -2.966  -18.190 18.860  1.00 51.33  ? 265 LEU A CA  1 
ATOM   2069  C  C   . LEU A 1 265 ? -4.419  -18.679 18.800  1.00 53.58  ? 265 LEU A C   1 
ATOM   2070  O  O   . LEU A 1 265 ? -5.169  -18.353 17.878  1.00 55.15  ? 265 LEU A O   1 
ATOM   2071  C  CB  . LEU A 1 265 ? -2.615  -17.332 17.632  1.00 49.83  ? 265 LEU A CB  1 
ATOM   2072  C  CG  . LEU A 1 265 ? -1.181  -16.809 17.417  1.00 45.71  ? 265 LEU A CG  1 
ATOM   2073  C  CD1 . LEU A 1 265 ? -1.041  -16.204 16.048  1.00 42.90  ? 265 LEU A CD1 1 
ATOM   2074  C  CD2 . LEU A 1 265 ? -0.801  -15.778 18.455  1.00 38.16  ? 265 LEU A CD2 1 
ATOM   2075  N  N   . ILE A 1 266 ? -4.819  -19.457 19.800  1.00 49.81  ? 266 ILE A N   1 
ATOM   2076  C  CA  . ILE A 1 266 ? -6.235  -19.807 19.933  1.00 54.76  ? 266 ILE A CA  1 
ATOM   2077  C  C   . ILE A 1 266 ? -7.004  -18.656 20.578  1.00 48.35  ? 266 ILE A C   1 
ATOM   2078  O  O   . ILE A 1 266 ? -6.704  -18.267 21.717  1.00 48.39  ? 266 ILE A O   1 
ATOM   2079  C  CB  . ILE A 1 266 ? -6.435  -21.116 20.713  1.00 53.64  ? 266 ILE A CB  1 
ATOM   2080  C  CG1 . ILE A 1 266 ? -5.833  -22.299 19.942  1.00 56.06  ? 266 ILE A CG1 1 
ATOM   2081  C  CG2 . ILE A 1 266 ? -7.909  -21.346 20.968  1.00 50.83  ? 266 ILE A CG2 1 
ATOM   2082  C  CD1 . ILE A 1 266 ? -5.202  -23.347 20.813  1.00 52.55  ? 266 ILE A CD1 1 
ATOM   2083  N  N   . PRO A 1 267 ? -7.993  -18.086 19.885  1.00 48.12  ? 267 PRO A N   1 
ATOM   2084  C  CA  . PRO A 1 267 ? -8.702  -16.913 20.417  1.00 39.10  ? 267 PRO A CA  1 
ATOM   2085  C  C   . PRO A 1 267 ? -9.346  -17.180 21.768  1.00 43.04  ? 267 PRO A C   1 
ATOM   2086  O  O   . PRO A 1 267 ? -9.602  -18.319 22.159  1.00 47.27  ? 267 PRO A O   1 
ATOM   2087  C  CB  . PRO A 1 267 ? -9.763  -16.609 19.350  1.00 41.61  ? 267 PRO A CB  1 
ATOM   2088  C  CG  . PRO A 1 267 ? -9.562  -17.628 18.235  1.00 47.57  ? 267 PRO A CG  1 
ATOM   2089  C  CD  . PRO A 1 267 ? -8.263  -18.317 18.455  1.00 43.62  ? 267 PRO A CD  1 
ATOM   2090  N  N   . HIS A 1 268 ? -9.569  -16.095 22.498  1.00 38.88  ? 268 HIS A N   1 
ATOM   2091  C  CA  . HIS A 1 268 ? -10.256 -16.143 23.777  1.00 36.47  ? 268 HIS A CA  1 
ATOM   2092  C  C   . HIS A 1 268 ? -11.619 -16.824 23.628  1.00 39.02  ? 268 HIS A C   1 
ATOM   2093  O  O   . HIS A 1 268 ? -12.283 -16.655 22.598  1.00 43.23  ? 268 HIS A O   1 
ATOM   2094  C  CB  . HIS A 1 268 ? -10.428 -14.718 24.275  1.00 34.53  ? 268 HIS A CB  1 
ATOM   2095  C  CG  . HIS A 1 268 ? -10.764 -14.609 25.723  1.00 36.61  ? 268 HIS A CG  1 
ATOM   2096  N  ND1 . HIS A 1 268 ? -12.057 -14.682 26.194  1.00 38.99  ? 268 HIS A ND1 1 
ATOM   2097  C  CD2 . HIS A 1 268 ? -9.980  -14.384 26.803  1.00 38.84  ? 268 HIS A CD2 1 
ATOM   2098  C  CE1 . HIS A 1 268 ? -12.053 -14.511 27.503  1.00 41.73  ? 268 HIS A CE1 1 
ATOM   2099  N  NE2 . HIS A 1 268 ? -10.804 -14.335 27.899  1.00 41.65  ? 268 HIS A NE2 1 
ATOM   2100  N  N   . PRO A 1 269 ? -12.082 -17.582 24.631  1.00 39.91  ? 269 PRO A N   1 
ATOM   2101  C  CA  . PRO A 1 269 ? -13.369 -18.285 24.490  1.00 40.02  ? 269 PRO A CA  1 
ATOM   2102  C  C   . PRO A 1 269 ? -14.573 -17.386 24.257  1.00 40.06  ? 269 PRO A C   1 
ATOM   2103  O  O   . PRO A 1 269 ? -15.623 -17.898 23.850  1.00 41.34  ? 269 PRO A O   1 
ATOM   2104  C  CB  . PRO A 1 269 ? -13.505 -19.038 25.818  1.00 39.98  ? 269 PRO A CB  1 
ATOM   2105  C  CG  . PRO A 1 269 ? -12.108 -19.217 26.274  1.00 42.26  ? 269 PRO A CG  1 
ATOM   2106  C  CD  . PRO A 1 269 ? -11.377 -17.989 25.858  1.00 37.27  ? 269 PRO A CD  1 
ATOM   2107  N  N   . ILE A 1 270 ? -14.486 -16.076 24.506  1.00 39.35  ? 270 ILE A N   1 
ATOM   2108  C  CA  . ILE A 1 270 ? -15.636 -15.225 24.195  1.00 33.85  ? 270 ILE A CA  1 
ATOM   2109  C  C   . ILE A 1 270 ? -15.789 -14.951 22.708  1.00 32.98  ? 270 ILE A C   1 
ATOM   2110  O  O   . ILE A 1 270 ? -16.812 -14.383 22.300  1.00 32.29  ? 270 ILE A O   1 
ATOM   2111  C  CB  . ILE A 1 270 ? -15.561 -13.869 24.911  1.00 29.51  ? 270 ILE A CB  1 
ATOM   2112  C  CG1 . ILE A 1 270 ? -14.358 -13.079 24.402  1.00 29.40  ? 270 ILE A CG1 1 
ATOM   2113  C  CG2 . ILE A 1 270 ? -15.433 -14.078 26.373  1.00 34.51  ? 270 ILE A CG2 1 
ATOM   2114  C  CD1 . ILE A 1 270 ? -14.394 -11.666 24.851  1.00 32.96  ? 270 ILE A CD1 1 
ATOM   2115  N  N   . TRP A 1 271 ? -14.820 -15.360 21.881  1.00 34.41  ? 271 TRP A N   1 
ATOM   2116  C  CA  . TRP A 1 271 ? -14.833 -14.941 20.484  1.00 32.39  ? 271 TRP A CA  1 
ATOM   2117  C  C   . TRP A 1 271 ? -16.077 -15.422 19.760  1.00 32.77  ? 271 TRP A C   1 
ATOM   2118  O  O   . TRP A 1 271 ? -16.588 -14.719 18.886  1.00 30.92  ? 271 TRP A O   1 
ATOM   2119  C  CB  . TRP A 1 271 ? -13.556 -15.404 19.773  1.00 38.68  ? 271 TRP A CB  1 
ATOM   2120  C  CG  . TRP A 1 271 ? -13.599 -16.779 19.173  1.00 43.46  ? 271 TRP A CG  1 
ATOM   2121  C  CD1 . TRP A 1 271 ? -13.073 -17.918 19.712  1.00 40.04  ? 271 TRP A CD1 1 
ATOM   2122  C  CD2 . TRP A 1 271 ? -14.179 -17.162 17.915  1.00 39.37  ? 271 TRP A CD2 1 
ATOM   2123  N  NE1 . TRP A 1 271 ? -13.294 -18.986 18.876  1.00 42.05  ? 271 TRP A NE1 1 
ATOM   2124  C  CE2 . TRP A 1 271 ? -13.977 -18.553 17.769  1.00 40.93  ? 271 TRP A CE2 1 
ATOM   2125  C  CE3 . TRP A 1 271 ? -14.864 -16.471 16.909  1.00 40.55  ? 271 TRP A CE3 1 
ATOM   2126  C  CZ2 . TRP A 1 271 ? -14.423 -19.268 16.653  1.00 39.57  ? 271 TRP A CZ2 1 
ATOM   2127  C  CZ3 . TRP A 1 271 ? -15.310 -17.187 15.792  1.00 46.68  ? 271 TRP A CZ3 1 
ATOM   2128  C  CH2 . TRP A 1 271 ? -15.084 -18.575 15.677  1.00 39.12  ? 271 TRP A CH2 1 
ATOM   2129  N  N   . THR A 1 272 ? -16.615 -16.582 20.134  1.00 34.02  ? 272 THR A N   1 
ATOM   2130  C  CA  . THR A 1 272 ? -17.705 -17.164 19.349  1.00 35.88  ? 272 THR A CA  1 
ATOM   2131  C  C   . THR A 1 272 ? -18.996 -16.389 19.543  1.00 27.59  ? 272 THR A C   1 
ATOM   2132  O  O   . THR A 1 272 ? -19.649 -15.992 18.574  1.00 32.94  ? 272 THR A O   1 
ATOM   2133  C  CB  . THR A 1 272 ? -17.903 -18.638 19.725  1.00 35.02  ? 272 THR A CB  1 
ATOM   2134  O  OG1 . THR A 1 272 ? -16.854 -19.409 19.137  1.00 29.29  ? 272 THR A OG1 1 
ATOM   2135  C  CG2 . THR A 1 272 ? -19.272 -19.157 19.229  1.00 26.75  ? 272 THR A CG2 1 
ATOM   2136  N  N   . GLU A 1 273 ? -19.375 -16.163 20.789  1.00 30.51  ? 273 GLU A N   1 
ATOM   2137  C  CA  . GLU A 1 273 ? -20.586 -15.409 21.060  1.00 31.44  ? 273 GLU A CA  1 
ATOM   2138  C  C   . GLU A 1 273 ? -20.424 -13.932 20.701  1.00 30.13  ? 273 GLU A C   1 
ATOM   2139  O  O   . GLU A 1 273 ? -21.416 -13.264 20.387  1.00 32.01  ? 273 GLU A O   1 
ATOM   2140  C  CB  . GLU A 1 273 ? -20.960 -15.576 22.531  1.00 32.00  ? 273 GLU A CB  1 
ATOM   2141  C  CG  . GLU A 1 273 ? -20.742 -16.987 23.099  1.00 35.34  ? 273 GLU A CG  1 
ATOM   2142  C  CD  . GLU A 1 273 ? -19.375 -17.199 23.792  1.00 45.95  ? 273 GLU A CD  1 
ATOM   2143  O  OE1 . GLU A 1 273 ? -18.320 -17.286 23.106  1.00 37.52  ? 273 GLU A OE1 1 
ATOM   2144  O  OE2 . GLU A 1 273 ? -19.364 -17.263 25.051  1.00 52.99  ? 273 GLU A OE2 1 
ATOM   2145  N  N   . VAL A 1 274 ? -19.194 -13.404 20.732  1.00 33.20  ? 274 VAL A N   1 
ATOM   2146  C  CA  . VAL A 1 274 ? -18.965 -12.023 20.284  1.00 25.99  ? 274 VAL A CA  1 
ATOM   2147  C  C   . VAL A 1 274 ? -19.287 -11.884 18.799  1.00 28.23  ? 274 VAL A C   1 
ATOM   2148  O  O   . VAL A 1 274 ? -19.963 -10.937 18.374  1.00 28.65  ? 274 VAL A O   1 
ATOM   2149  C  CB  . VAL A 1 274 ? -17.518 -11.585 20.592  1.00 26.30  ? 274 VAL A CB  1 
ATOM   2150  C  CG1 . VAL A 1 274 ? -17.159 -10.320 19.770  1.00 27.85  ? 274 VAL A CG1 1 
ATOM   2151  C  CG2 . VAL A 1 274 ? -17.342 -11.315 22.076  1.00 31.30  ? 274 VAL A CG2 1 
ATOM   2152  N  N   . VAL A 1 275 ? -18.823 -12.838 17.988  1.00 31.63  ? 275 VAL A N   1 
ATOM   2153  C  CA  . VAL A 1 275 ? -19.126 -12.842 16.560  1.00 24.22  ? 275 VAL A CA  1 
ATOM   2154  C  C   . VAL A 1 275 ? -20.613 -13.092 16.315  1.00 36.88  ? 275 VAL A C   1 
ATOM   2155  O  O   . VAL A 1 275 ? -21.257 -12.369 15.539  1.00 32.80  ? 275 VAL A O   1 
ATOM   2156  C  CB  . VAL A 1 275 ? -18.249 -13.885 15.834  1.00 31.92  ? 275 VAL A CB  1 
ATOM   2157  C  CG1 . VAL A 1 275 ? -18.774 -14.149 14.422  1.00 30.40  ? 275 VAL A CG1 1 
ATOM   2158  C  CG2 . VAL A 1 275 ? -16.797 -13.416 15.785  1.00 31.21  ? 275 VAL A CG2 1 
ATOM   2159  N  N   . GLU A 1 276 ? -21.177 -14.128 16.963  1.00 33.93  ? 276 GLU A N   1 
ATOM   2160  C  CA  . GLU A 1 276 ? -22.582 -14.482 16.757  1.00 31.38  ? 276 GLU A CA  1 
ATOM   2161  C  C   . GLU A 1 276 ? -23.492 -13.311 17.069  1.00 31.54  ? 276 GLU A C   1 
ATOM   2162  O  O   . GLU A 1 276 ? -24.395 -12.993 16.288  1.00 34.20  ? 276 GLU A O   1 
ATOM   2163  C  CB  . GLU A 1 276 ? -22.964 -15.695 17.622  1.00 32.05  ? 276 GLU A CB  1 
ATOM   2164  C  CG  . GLU A 1 276 ? -22.273 -16.975 17.157  1.00 39.13  ? 276 GLU A CG  1 
ATOM   2165  C  CD  . GLU A 1 276 ? -23.036 -18.270 17.465  1.00 45.85  ? 276 GLU A CD  1 
ATOM   2166  O  OE1 . GLU A 1 276 ? -24.159 -18.217 18.025  1.00 43.15  ? 276 GLU A OE1 1 
ATOM   2167  O  OE2 . GLU A 1 276 ? -22.487 -19.347 17.137  1.00 46.02  ? 276 GLU A OE2 1 
ATOM   2168  N  N   . ALA A 1 277 ? -23.272 -12.652 18.214  1.00 28.65  ? 277 ALA A N   1 
ATOM   2169  C  CA  . ALA A 1 277 ? -24.035 -11.466 18.565  1.00 26.52  ? 277 ALA A CA  1 
ATOM   2170  C  C   . ALA A 1 277 ? -23.798 -10.300 17.602  1.00 34.68  ? 277 ALA A C   1 
ATOM   2171  O  O   . ALA A 1 277 ? -24.525 -9.303  17.669  1.00 35.62  ? 277 ALA A O   1 
ATOM   2172  C  CB  . ALA A 1 277 ? -23.676 -11.036 19.982  1.00 28.37  ? 277 ALA A CB  1 
ATOM   2173  N  N   . SER A 1 278 ? -22.792 -10.384 16.728  1.00 28.36  ? 278 SER A N   1 
ATOM   2174  C  CA  . SER A 1 278 ? -22.480 -9.278  15.831  1.00 34.20  ? 278 SER A CA  1 
ATOM   2175  C  C   . SER A 1 278 ? -22.890 -9.532  14.394  1.00 32.89  ? 278 SER A C   1 
ATOM   2176  O  O   . SER A 1 278 ? -22.956 -8.579  13.613  1.00 31.22  ? 278 SER A O   1 
ATOM   2177  C  CB  . SER A 1 278 ? -20.974 -8.965  15.846  1.00 30.96  ? 278 SER A CB  1 
ATOM   2178  O  OG  . SER A 1 278 ? -20.528 -8.642  17.140  1.00 33.07  ? 278 SER A OG  1 
ATOM   2179  N  N   . LEU A 1 279 ? -23.169 -10.783 14.034  1.00 35.87  ? 279 LEU A N   1 
ATOM   2180  C  CA  . LEU A 1 279 ? -23.523 -11.093 12.653  1.00 35.28  ? 279 LEU A CA  1 
ATOM   2181  C  C   . LEU A 1 279 ? -24.819 -10.450 12.161  1.00 36.68  ? 279 LEU A C   1 
ATOM   2182  O  O   . LEU A 1 279 ? -24.876 -10.119 10.963  1.00 39.51  ? 279 LEU A O   1 
ATOM   2183  C  CB  . LEU A 1 279 ? -23.586 -12.615 12.474  1.00 33.77  ? 279 LEU A CB  1 
ATOM   2184  C  CG  . LEU A 1 279 ? -22.204 -13.225 12.294  1.00 37.06  ? 279 LEU A CG  1 
ATOM   2185  C  CD1 . LEU A 1 279 ? -22.279 -14.704 12.580  1.00 35.58  ? 279 LEU A CD1 1 
ATOM   2186  C  CD2 . LEU A 1 279 ? -21.715 -12.963 10.876  1.00 29.96  ? 279 LEU A CD2 1 
ATOM   2187  N  N   . PRO A 1 280 ? -25.876 -10.275 12.972  1.00 39.37  ? 280 PRO A N   1 
ATOM   2188  C  CA  . PRO A 1 280 ? -27.051 -9.552  12.449  1.00 36.18  ? 280 PRO A CA  1 
ATOM   2189  C  C   . PRO A 1 280 ? -26.711 -8.149  11.980  1.00 40.06  ? 280 PRO A C   1 
ATOM   2190  O  O   . PRO A 1 280 ? -27.221 -7.689  10.945  1.00 40.21  ? 280 PRO A O   1 
ATOM   2191  C  CB  . PRO A 1 280 ? -28.014 -9.537  13.640  1.00 34.80  ? 280 PRO A CB  1 
ATOM   2192  C  CG  . PRO A 1 280 ? -27.604 -10.688 14.468  1.00 38.05  ? 280 PRO A CG  1 
ATOM   2193  C  CD  . PRO A 1 280 ? -26.125 -10.810 14.325  1.00 32.52  ? 280 PRO A CD  1 
ATOM   2194  N  N   . LEU A 1 281 ? -25.840 -7.455  12.712  1.00 37.90  ? 281 LEU A N   1 
ATOM   2195  C  CA  . LEU A 1 281 ? -25.494 -6.096  12.321  1.00 38.31  ? 281 LEU A CA  1 
ATOM   2196  C  C   . LEU A 1 281 ? -24.638 -6.094  11.064  1.00 31.72  ? 281 LEU A C   1 
ATOM   2197  O  O   . LEU A 1 281 ? -24.802 -5.224  10.204  1.00 36.34  ? 281 LEU A O   1 
ATOM   2198  C  CB  . LEU A 1 281 ? -24.783 -5.371  13.466  1.00 34.04  ? 281 LEU A CB  1 
ATOM   2199  C  CG  . LEU A 1 281 ? -24.255 -3.983  13.099  1.00 31.88  ? 281 LEU A CG  1 
ATOM   2200  C  CD1 . LEU A 1 281 ? -25.396 -3.003  12.822  1.00 31.37  ? 281 LEU A CD1 1 
ATOM   2201  C  CD2 . LEU A 1 281 ? -23.303 -3.457  14.162  1.00 31.20  ? 281 LEU A CD2 1 
ATOM   2202  N  N   . ALA A 1 282 ? -23.724 -7.062  10.935  1.00 36.54  ? 282 ALA A N   1 
ATOM   2203  C  CA  . ALA A 1 282 ? -22.883 -7.124  9.743   1.00 35.81  ? 282 ALA A CA  1 
ATOM   2204  C  C   . ALA A 1 282 ? -23.689 -7.474  8.508   1.00 35.93  ? 282 ALA A C   1 
ATOM   2205  O  O   . ALA A 1 282 ? -23.354 -7.047  7.395   1.00 39.71  ? 282 ALA A O   1 
ATOM   2206  C  CB  . ALA A 1 282 ? -21.763 -8.140  9.925   1.00 29.71  ? 282 ALA A CB  1 
ATOM   2207  N  N   . GLU A 1 283 ? -24.721 -8.280  8.676   1.00 38.38  ? 283 GLU A N   1 
ATOM   2208  C  CA  . GLU A 1 283 ? -25.622 -8.544  7.570   1.00 36.54  ? 283 GLU A CA  1 
ATOM   2209  C  C   . GLU A 1 283 ? -26.439 -7.299  7.250   1.00 34.77  ? 283 GLU A C   1 
ATOM   2210  O  O   . GLU A 1 283 ? -26.595 -6.938  6.082   1.00 38.59  ? 283 GLU A O   1 
ATOM   2211  C  CB  . GLU A 1 283 ? -26.494 -9.748  7.934   1.00 43.96  ? 283 GLU A CB  1 
ATOM   2212  C  CG  . GLU A 1 283 ? -27.845 -9.868  7.260   1.00 51.91  ? 283 GLU A CG  1 
ATOM   2213  C  CD  . GLU A 1 283 ? -28.588 -11.118 7.729   1.00 56.04  ? 283 GLU A CD  1 
ATOM   2214  O  OE1 . GLU A 1 283 ? -28.249 -11.631 8.821   1.00 52.82  ? 283 GLU A OE1 1 
ATOM   2215  O  OE2 . GLU A 1 283 ? -29.503 -11.582 7.012   1.00 57.67  ? 283 GLU A OE2 1 
ATOM   2216  N  N   . GLU A 1 284 ? -26.919 -6.599  8.283   1.00 34.96  ? 284 GLU A N   1 
ATOM   2217  C  CA  . GLU A 1 284 ? -27.699 -5.389  8.060   1.00 34.42  ? 284 GLU A CA  1 
ATOM   2218  C  C   . GLU A 1 284 ? -26.869 -4.322  7.354   1.00 39.47  ? 284 GLU A C   1 
ATOM   2219  O  O   . GLU A 1 284 ? -27.361 -3.639  6.449   1.00 36.02  ? 284 GLU A O   1 
ATOM   2220  C  CB  . GLU A 1 284 ? -28.234 -4.868  9.394   1.00 38.43  ? 284 GLU A CB  1 
ATOM   2221  C  CG  . GLU A 1 284 ? -29.190 -3.700  9.264   1.00 38.52  ? 284 GLU A CG  1 
ATOM   2222  C  CD  . GLU A 1 284 ? -29.219 -2.829  10.506  1.00 47.27  ? 284 GLU A CD  1 
ATOM   2223  O  OE1 . GLU A 1 284 ? -29.576 -3.344  11.587  1.00 50.96  ? 284 GLU A OE1 1 
ATOM   2224  O  OE2 . GLU A 1 284 ? -28.875 -1.628  10.403  1.00 50.49  ? 284 GLU A OE2 1 
ATOM   2225  N  N   . LEU A 1 285 ? -25.597 -4.187  7.731   1.00 33.87  ? 285 LEU A N   1 
ATOM   2226  C  CA  . LEU A 1 285 ? -24.718 -3.183  7.140   1.00 35.95  ? 285 LEU A CA  1 
ATOM   2227  C  C   . LEU A 1 285 ? -24.034 -3.654  5.858   1.00 36.48  ? 285 LEU A C   1 
ATOM   2228  O  O   . LEU A 1 285 ? -23.378 -2.842  5.195   1.00 33.69  ? 285 LEU A O   1 
ATOM   2229  C  CB  . LEU A 1 285 ? -23.649 -2.752  8.157   1.00 31.44  ? 285 LEU A CB  1 
ATOM   2230  C  CG  . LEU A 1 285 ? -24.103 -2.052  9.451   1.00 35.68  ? 285 LEU A CG  1 
ATOM   2231  C  CD1 . LEU A 1 285 ? -22.927 -1.757  10.382  1.00 31.40  ? 285 LEU A CD1 1 
ATOM   2232  C  CD2 . LEU A 1 285 ? -24.888 -0.770  9.208   1.00 27.32  ? 285 LEU A CD2 1 
ATOM   2233  N  N   . ASP A 1 286 ? -24.185 -4.930  5.485   1.00 37.76  ? 286 ASP A N   1 
ATOM   2234  C  CA  . ASP A 1 286 ? -23.501 -5.508  4.325   1.00 34.41  ? 286 ASP A CA  1 
ATOM   2235  C  C   . ASP A 1 286 ? -21.981 -5.437  4.470   1.00 35.98  ? 286 ASP A C   1 
ATOM   2236  O  O   . ASP A 1 286 ? -21.267 -5.136  3.512   1.00 38.03  ? 286 ASP A O   1 
ATOM   2237  C  CB  . ASP A 1 286 ? -23.941 -4.842  3.020   1.00 39.83  ? 286 ASP A CB  1 
ATOM   2238  C  CG  . ASP A 1 286 ? -23.806 -5.771  1.832   1.00 40.79  ? 286 ASP A CG  1 
ATOM   2239  O  OD1 . ASP A 1 286 ? -23.578 -6.972  2.073   1.00 35.06  ? 286 ASP A OD1 1 
ATOM   2240  O  OD2 . ASP A 1 286 ? -23.926 -5.306  0.676   1.00 50.01  ? 286 ASP A OD2 1 
ATOM   2241  N  N   . VAL A 1 287 ? -21.483 -5.724  5.674   1.00 35.81  ? 287 VAL A N   1 
ATOM   2242  C  CA  . VAL A 1 287 ? -20.051 -5.800  5.959   1.00 36.57  ? 287 VAL A CA  1 
ATOM   2243  C  C   . VAL A 1 287 ? -19.723 -7.239  6.333   1.00 33.67  ? 287 VAL A C   1 
ATOM   2244  O  O   . VAL A 1 287 ? -20.463 -7.865  7.099   1.00 37.85  ? 287 VAL A O   1 
ATOM   2245  C  CB  . VAL A 1 287 ? -19.650 -4.830  7.094   1.00 33.10  ? 287 VAL A CB  1 
ATOM   2246  C  CG1 . VAL A 1 287 ? -18.192 -4.975  7.443   1.00 31.65  ? 287 VAL A CG1 1 
ATOM   2247  C  CG2 . VAL A 1 287 ? -19.933 -3.396  6.691   1.00 32.01  ? 287 VAL A CG2 1 
ATOM   2248  N  N   . ILE A 1 288 ? -18.623 -7.769  5.808   1.00 29.43  ? 288 ILE A N   1 
ATOM   2249  C  CA  . ILE A 1 288 ? -18.212 -9.134  6.120   1.00 32.59  ? 288 ILE A CA  1 
ATOM   2250  C  C   . ILE A 1 288 ? -17.163 -9.113  7.227   1.00 33.76  ? 288 ILE A C   1 
ATOM   2251  O  O   . ILE A 1 288 ? -16.177 -8.366  7.152   1.00 26.76  ? 288 ILE A O   1 
ATOM   2252  C  CB  . ILE A 1 288 ? -17.681 -9.861  4.876   1.00 28.30  ? 288 ILE A CB  1 
ATOM   2253  C  CG1 . ILE A 1 288 ? -18.797 -10.019 3.848   1.00 28.99  ? 288 ILE A CG1 1 
ATOM   2254  C  CG2 . ILE A 1 288 ? -17.089 -11.201 5.285   1.00 27.20  ? 288 ILE A CG2 1 
ATOM   2255  C  CD1 . ILE A 1 288 ? -18.345 -10.663 2.554   1.00 32.23  ? 288 ILE A CD1 1 
ATOM   2256  N  N   . ILE A 1 289 ? -17.378 -9.931  8.255   1.00 31.43  ? 289 ILE A N   1 
ATOM   2257  C  CA  . ILE A 1 289 ? -16.411 -10.139 9.328   1.00 29.50  ? 289 ILE A CA  1 
ATOM   2258  C  C   . ILE A 1 289 ? -15.475 -11.258 8.904   1.00 31.99  ? 289 ILE A C   1 
ATOM   2259  O  O   . ILE A 1 289 ? -15.912 -12.398 8.732   1.00 33.35  ? 289 ILE A O   1 
ATOM   2260  C  CB  . ILE A 1 289 ? -17.110 -10.500 10.650  1.00 33.97  ? 289 ILE A CB  1 
ATOM   2261  C  CG1 . ILE A 1 289 ? -18.106 -9.431  11.081  1.00 29.16  ? 289 ILE A CG1 1 
ATOM   2262  C  CG2 . ILE A 1 289 ? -16.102 -10.783 11.757  1.00 32.67  ? 289 ILE A CG2 1 
ATOM   2263  C  CD1 . ILE A 1 289 ? -19.206 -9.990  11.916  1.00 26.70  ? 289 ILE A CD1 1 
ATOM   2264  N  N   . CYS A 1 290 ? -14.186 -10.953 8.774   1.00 31.09  ? 290 CYS A N   1 
ATOM   2265  C  CA  . CYS A 1 290 ? -13.198 -11.939 8.338   1.00 32.63  ? 290 CYS A CA  1 
ATOM   2266  C  C   . CYS A 1 290 ? -11.982 -11.933 9.248   1.00 30.21  ? 290 CYS A C   1 
ATOM   2267  O  O   . CYS A 1 290 ? -11.059 -11.122 9.055   1.00 29.74  ? 290 CYS A O   1 
ATOM   2268  C  CB  . CYS A 1 290 ? -12.776 -11.709 6.893   1.00 29.58  ? 290 CYS A CB  1 
ATOM   2269  S  SG  . CYS A 1 290 ? -12.505 -9.970  6.462   1.00 37.12  ? 290 CYS A SG  1 
ATOM   2270  N  N   . PRO A 1 291 ? -11.929 -12.838 10.224  1.00 31.26  ? 291 PRO A N   1 
ATOM   2271  C  CA  . PRO A 1 291 ? -10.717 -12.983 11.032  1.00 24.22  ? 291 PRO A CA  1 
ATOM   2272  C  C   . PRO A 1 291 ? -9.553  -13.413 10.169  1.00 25.29  ? 291 PRO A C   1 
ATOM   2273  O  O   . PRO A 1 291 ? -9.718  -14.024 9.111   1.00 29.53  ? 291 PRO A O   1 
ATOM   2274  C  CB  . PRO A 1 291 ? -11.077 -14.070 12.061  1.00 31.72  ? 291 PRO A CB  1 
ATOM   2275  C  CG  . PRO A 1 291 ? -12.414 -14.604 11.664  1.00 32.55  ? 291 PRO A CG  1 
ATOM   2276  C  CD  . PRO A 1 291 ? -13.070 -13.593 10.764  1.00 30.03  ? 291 PRO A CD  1 
ATOM   2277  N  N   . GLU A 1 292 ? -8.362  -13.096 10.653  1.00 27.87  ? 292 GLU A N   1 
ATOM   2278  C  CA  . GLU A 1 292 ? -7.131  -13.248 9.901   1.00 26.96  ? 292 GLU A CA  1 
ATOM   2279  C  C   . GLU A 1 292 ? -6.401  -14.513 10.333  1.00 27.84  ? 292 GLU A C   1 
ATOM   2280  O  O   . GLU A 1 292 ? -6.193  -14.738 11.528  1.00 31.51  ? 292 GLU A O   1 
ATOM   2281  C  CB  . GLU A 1 292 ? -6.239  -12.022 10.101  1.00 27.97  ? 292 GLU A CB  1 
ATOM   2282  C  CG  . GLU A 1 292 ? -4.831  -12.238 9.660   1.00 28.14  ? 292 GLU A CG  1 
ATOM   2283  C  CD  . GLU A 1 292 ? -3.917  -11.051 9.951   1.00 27.16  ? 292 GLU A CD  1 
ATOM   2284  O  OE1 . GLU A 1 292 ? -4.293  -10.116 10.692  1.00 33.05  ? 292 GLU A OE1 1 
ATOM   2285  O  OE2 . GLU A 1 292 ? -2.794  -11.072 9.457   1.00 23.23  ? 292 GLU A OE2 1 
ATOM   2286  N  N   . ILE A 1 293 ? -6.026  -15.329 9.354   1.00 25.45  ? 293 ILE A N   1 
ATOM   2287  C  CA  . ILE A 1 293 ? -5.176  -16.506 9.533   1.00 32.69  ? 293 ILE A CA  1 
ATOM   2288  C  C   . ILE A 1 293 ? -3.747  -16.070 9.235   1.00 34.15  ? 293 ILE A C   1 
ATOM   2289  O  O   . ILE A 1 293 ? -3.393  -15.868 8.063   1.00 31.71  ? 293 ILE A O   1 
ATOM   2290  C  CB  . ILE A 1 293 ? -5.576  -17.656 8.588   1.00 28.59  ? 293 ILE A CB  1 
ATOM   2291  C  CG1 . ILE A 1 293 ? -7.078  -17.944 8.631   1.00 25.64  ? 293 ILE A CG1 1 
ATOM   2292  C  CG2 . ILE A 1 293 ? -4.761  -18.894 8.868   1.00 30.11  ? 293 ILE A CG2 1 
ATOM   2293  C  CD1 . ILE A 1 293 ? -7.634  -18.049 10.012  1.00 37.97  ? 293 ILE A CD1 1 
ATOM   2294  N  N   . HIS A 1 294 ? -2.944  -15.950 10.289  1.00 27.84  ? 294 HIS A N   1 
ATOM   2295  C  CA  . HIS A 1 294 ? -1.528  -15.529 10.111  1.00 34.44  ? 294 HIS A CA  1 
ATOM   2296  C  C   . HIS A 1 294 ? -0.548  -16.468 10.829  1.00 32.72  ? 294 HIS A C   1 
ATOM   2297  O  O   . HIS A 1 294 ? -0.939  -17.183 11.761  1.00 32.79  ? 294 HIS A O   1 
ATOM   2298  C  CB  . HIS A 1 294 ? -1.344  -14.067 10.530  1.00 37.16  ? 294 HIS A CB  1 
ATOM   2299  C  CG  . HIS A 1 294 ? -1.437  -13.824 11.991  1.00 37.09  ? 294 HIS A CG  1 
ATOM   2300  N  ND1 . HIS A 1 294 ? -0.471  -13.125 12.678  1.00 39.26  ? 294 HIS A ND1 1 
ATOM   2301  C  CD2 . HIS A 1 294 ? -2.360  -14.168 12.889  1.00 43.58  ? 294 HIS A CD2 1 
ATOM   2302  C  CE1 . HIS A 1 294 ? -0.816  -13.054 13.952  1.00 42.25  ? 294 HIS A CE1 1 
ATOM   2303  N  NE2 . HIS A 1 294 ? -1.958  -13.684 14.100  1.00 51.08  ? 294 HIS A NE2 1 
ATOM   2304  N  N   . SER A 1 295 ? 0.707   -16.450 10.380  1.00 33.88  ? 295 SER A N   1 
ATOM   2305  C  CA  . SER A 1 295 ? 1.732   -17.298 10.984  1.00 34.48  ? 295 SER A CA  1 
ATOM   2306  C  C   . SER A 1 295 ? 1.802   -17.033 12.484  1.00 35.42  ? 295 SER A C   1 
ATOM   2307  O  O   . SER A 1 295 ? 1.774   -15.870 12.902  1.00 38.09  ? 295 SER A O   1 
ATOM   2308  C  CB  . SER A 1 295 ? 3.098   -17.032 10.340  1.00 36.19  ? 295 SER A CB  1 
ATOM   2309  O  OG  . SER A 1 295 ? 4.060   -18.030 10.647  1.00 33.87  ? 295 SER A OG  1 
ATOM   2310  N  N   . PRO A 1 296 ? 1.931   -18.083 13.326  1.00 35.96  ? 296 PRO A N   1 
ATOM   2311  C  CA  . PRO A 1 296 ? 2.213   -19.485 12.989  1.00 30.86  ? 296 PRO A CA  1 
ATOM   2312  C  C   . PRO A 1 296 ? 0.969   -20.350 12.783  1.00 35.18  ? 296 PRO A C   1 
ATOM   2313  O  O   . PRO A 1 296 ? 1.092   -21.563 12.701  1.00 34.57  ? 296 PRO A O   1 
ATOM   2314  C  CB  . PRO A 1 296 ? 2.971   -19.968 14.212  1.00 30.96  ? 296 PRO A CB  1 
ATOM   2315  C  CG  . PRO A 1 296 ? 2.202   -19.302 15.334  1.00 30.97  ? 296 PRO A CG  1 
ATOM   2316  C  CD  . PRO A 1 296 ? 1.796   -17.920 14.786  1.00 33.49  ? 296 PRO A CD  1 
ATOM   2317  N  N   . THR A 1 297 ? -0.205  -19.757 12.717  1.00 32.07  ? 297 THR A N   1 
ATOM   2318  C  CA  . THR A 1 297 ? -1.388  -20.559 12.473  1.00 32.46  ? 297 THR A CA  1 
ATOM   2319  C  C   . THR A 1 297 ? -1.422  -21.013 11.016  1.00 30.37  ? 297 THR A C   1 
ATOM   2320  O  O   . THR A 1 297 ? -1.348  -20.166 10.118  1.00 34.18  ? 297 THR A O   1 
ATOM   2321  C  CB  . THR A 1 297 ? -2.621  -19.761 12.802  1.00 26.95  ? 297 THR A CB  1 
ATOM   2322  O  OG1 . THR A 1 297 ? -2.411  -19.070 14.031  1.00 32.21  ? 297 THR A OG1 1 
ATOM   2323  C  CG2 . THR A 1 297 ? -3.778  -20.693 12.962  1.00 33.28  ? 297 THR A CG2 1 
ATOM   2324  N  N   . PRO A 1 298 ? -1.492  -22.316 10.728  1.00 26.90  ? 298 PRO A N   1 
ATOM   2325  C  CA  . PRO A 1 298 ? -1.558  -22.739 9.325   1.00 28.38  ? 298 PRO A CA  1 
ATOM   2326  C  C   . PRO A 1 298 ? -3.001  -22.805 8.851   1.00 30.69  ? 298 PRO A C   1 
ATOM   2327  O  O   . PRO A 1 298 ? -3.898  -22.427 9.610   1.00 29.37  ? 298 PRO A O   1 
ATOM   2328  C  CB  . PRO A 1 298 ? -0.866  -24.106 9.333   1.00 32.03  ? 298 PRO A CB  1 
ATOM   2329  C  CG  . PRO A 1 298 ? -1.038  -24.621 10.736  1.00 32.95  ? 298 PRO A CG  1 
ATOM   2330  C  CD  . PRO A 1 298 ? -1.331  -23.457 11.650  1.00 28.64  ? 298 PRO A CD  1 
ATOM   2331  N  N   . ILE A 1 299 ? -3.250  -23.205 7.597   1.00 27.35  ? 299 ILE A N   1 
ATOM   2332  C  CA  . ILE A 1 299 ? -4.633  -23.360 7.160   1.00 27.15  ? 299 ILE A CA  1 
ATOM   2333  C  C   . ILE A 1 299 ? -5.276  -24.554 7.863   1.00 32.92  ? 299 ILE A C   1 
ATOM   2334  O  O   . ILE A 1 299 ? -6.434  -24.488 8.292   1.00 30.42  ? 299 ILE A O   1 
ATOM   2335  C  CB  . ILE A 1 299 ? -4.709  -23.495 5.626   1.00 34.47  ? 299 ILE A CB  1 
ATOM   2336  C  CG1 . ILE A 1 299 ? -4.339  -22.168 4.943   1.00 32.71  ? 299 ILE A CG1 1 
ATOM   2337  C  CG2 . ILE A 1 299 ? -6.094  -23.947 5.199   1.00 33.63  ? 299 ILE A CG2 1 
ATOM   2338  C  CD1 . ILE A 1 299 ? -4.282  -22.261 3.442   1.00 34.16  ? 299 ILE A CD1 1 
ATOM   2339  N  N   . LYS A 1 300 ? -4.531  -25.652 8.008   1.00 33.43  ? 300 LYS A N   1 
ATOM   2340  C  CA  . LYS A 1 300 ? -5.021  -26.870 8.663   1.00 34.49  ? 300 LYS A CA  1 
ATOM   2341  C  C   . LYS A 1 300 ? -4.803  -26.737 10.164  1.00 28.26  ? 300 LYS A C   1 
ATOM   2342  O  O   . LYS A 1 300 ? -3.714  -27.022 10.670  1.00 35.50  ? 300 LYS A O   1 
ATOM   2343  C  CB  . LYS A 1 300 ? -4.305  -28.097 8.108   1.00 30.95  ? 300 LYS A CB  1 
ATOM   2344  C  CG  . LYS A 1 300 ? -4.305  -28.189 6.586   1.00 32.88  ? 300 LYS A CG  1 
ATOM   2345  C  CD  . LYS A 1 300 ? -4.978  -29.457 6.082   1.00 41.92  ? 300 LYS A CD  1 
ATOM   2346  C  CE  . LYS A 1 300 ? -4.972  -29.525 4.551   1.00 43.93  ? 300 LYS A CE  1 
ATOM   2347  N  NZ  . LYS A 1 300 ? -3.630  -29.901 4.015   1.00 41.72  ? 300 LYS A NZ  1 
ATOM   2348  N  N   . HIS A 1 301 ? -5.840  -26.322 10.886  1.00 27.24  ? 301 HIS A N   1 
ATOM   2349  C  CA  . HIS A 1 301 ? -5.665  -26.014 12.305  1.00 33.16  ? 301 HIS A CA  1 
ATOM   2350  C  C   . HIS A 1 301 ? -7.029  -25.812 12.952  1.00 33.09  ? 301 HIS A C   1 
ATOM   2351  O  O   . HIS A 1 301 ? -7.972  -25.348 12.303  1.00 35.49  ? 301 HIS A O   1 
ATOM   2352  C  CB  . HIS A 1 301 ? -4.793  -24.764 12.500  1.00 33.53  ? 301 HIS A CB  1 
ATOM   2353  C  CG  . HIS A 1 301 ? -4.337  -24.559 13.909  1.00 26.16  ? 301 HIS A CG  1 
ATOM   2354  N  ND1 . HIS A 1 301 ? -5.147  -24.022 14.886  1.00 34.75  ? 301 HIS A ND1 1 
ATOM   2355  C  CD2 . HIS A 1 301 ? -3.151  -24.828 14.508  1.00 27.64  ? 301 HIS A CD2 1 
ATOM   2356  C  CE1 . HIS A 1 301 ? -4.481  -23.963 16.026  1.00 36.18  ? 301 HIS A CE1 1 
ATOM   2357  N  NE2 . HIS A 1 301 ? -3.269  -24.454 15.825  1.00 36.01  ? 301 HIS A NE2 1 
ATOM   2358  N  N   . GLU A 1 302 ? -7.116  -26.130 14.249  1.00 29.52  ? 302 GLU A N   1 
ATOM   2359  C  CA  . GLU A 1 302 ? -8.424  -26.130 14.902  1.00 38.33  ? 302 GLU A CA  1 
ATOM   2360  C  C   . GLU A 1 302 ? -9.088  -24.751 14.863  1.00 41.27  ? 302 GLU A C   1 
ATOM   2361  O  O   . GLU A 1 302 ? -10.324 -24.659 14.897  1.00 41.14  ? 302 GLU A O   1 
ATOM   2362  C  CB  . GLU A 1 302 ? -8.307  -26.653 16.348  1.00 39.98  ? 302 GLU A CB  1 
ATOM   2363  C  CG  . GLU A 1 302 ? -7.579  -25.734 17.339  1.00 44.47  ? 302 GLU A CG  1 
ATOM   2364  C  CD  . GLU A 1 302 ? -7.443  -26.331 18.742  1.00 53.27  ? 302 GLU A CD  1 
ATOM   2365  O  OE1 . GLU A 1 302 ? -8.380  -26.172 19.561  1.00 60.11  ? 302 GLU A OE1 1 
ATOM   2366  O  OE2 . GLU A 1 302 ? -6.390  -26.943 19.029  1.00 51.51  ? 302 GLU A OE2 1 
ATOM   2367  N  N   . VAL A 1 303 ? -8.307  -23.673 14.764  1.00 34.84  ? 303 VAL A N   1 
ATOM   2368  C  CA  . VAL A 1 303 ? -8.954  -22.363 14.756  1.00 40.10  ? 303 VAL A CA  1 
ATOM   2369  C  C   . VAL A 1 303 ? -9.588  -22.083 13.403  1.00 38.39  ? 303 VAL A C   1 
ATOM   2370  O  O   . VAL A 1 303 ? -10.619 -21.405 13.331  1.00 33.94  ? 303 VAL A O   1 
ATOM   2371  C  CB  . VAL A 1 303 ? -7.978  -21.240 15.135  1.00 43.89  ? 303 VAL A CB  1 
ATOM   2372  C  CG1 . VAL A 1 303 ? -7.519  -21.369 16.599  1.00 44.87  ? 303 VAL A CG1 1 
ATOM   2373  C  CG2 . VAL A 1 303 ? -6.824  -21.230 14.200  1.00 37.12  ? 303 VAL A CG2 1 
ATOM   2374  N  N   . VAL A 1 304 ? -8.995  -22.576 12.312  1.00 39.11  ? 304 VAL A N   1 
ATOM   2375  C  CA  . VAL A 1 304 ? -9.663  -22.442 11.027  1.00 34.44  ? 304 VAL A CA  1 
ATOM   2376  C  C   . VAL A 1 304 ? -10.911 -23.305 11.002  1.00 34.25  ? 304 VAL A C   1 
ATOM   2377  O  O   . VAL A 1 304 ? -11.992 -22.852 10.599  1.00 31.45  ? 304 VAL A O   1 
ATOM   2378  C  CB  . VAL A 1 304 ? -8.708  -22.785 9.873   1.00 34.29  ? 304 VAL A CB  1 
ATOM   2379  C  CG1 . VAL A 1 304 ? -9.427  -22.604 8.519   1.00 31.08  ? 304 VAL A CG1 1 
ATOM   2380  C  CG2 . VAL A 1 304 ? -7.488  -21.905 9.936   1.00 35.84  ? 304 VAL A CG2 1 
ATOM   2381  N  N   . ASP A 1 305 ? -10.796 -24.548 11.472  1.00 36.21  ? 305 ASP A N   1 
ATOM   2382  C  CA  . ASP A 1 305 ? -11.954 -25.433 11.480  1.00 38.13  ? 305 ASP A CA  1 
ATOM   2383  C  C   . ASP A 1 305 ? -13.103 -24.812 12.249  1.00 31.87  ? 305 ASP A C   1 
ATOM   2384  O  O   . ASP A 1 305 ? -14.260 -24.894 11.820  1.00 32.54  ? 305 ASP A O   1 
ATOM   2385  C  CB  . ASP A 1 305 ? -11.577 -26.793 12.065  1.00 35.94  ? 305 ASP A CB  1 
ATOM   2386  C  CG  . ASP A 1 305 ? -10.458 -27.453 11.293  1.00 41.50  ? 305 ASP A CG  1 
ATOM   2387  O  OD1 . ASP A 1 305 ? -10.248 -27.067 10.120  1.00 43.41  ? 305 ASP A OD1 1 
ATOM   2388  O  OD2 . ASP A 1 305 ? -9.782  -28.338 11.859  1.00 47.88  ? 305 ASP A OD2 1 
ATOM   2389  N  N   . ASP A 1 306 ? -12.800 -24.146 13.367  1.00 33.94  ? 306 ASP A N   1 
ATOM   2390  C  CA  . ASP A 1 306 ? -13.867 -23.531 14.141  1.00 27.42  ? 306 ASP A CA  1 
ATOM   2391  C  C   . ASP A 1 306 ? -14.445 -22.327 13.418  1.00 30.26  ? 306 ASP A C   1 
ATOM   2392  O  O   . ASP A 1 306 ? -15.655 -22.105 13.453  1.00 33.91  ? 306 ASP A O   1 
ATOM   2393  C  CB  . ASP A 1 306 ? -13.367 -23.175 15.537  1.00 31.21  ? 306 ASP A CB  1 
ATOM   2394  C  CG  . ASP A 1 306 ? -12.924 -24.414 16.326  1.00 45.16  ? 306 ASP A CG  1 
ATOM   2395  O  OD1 . ASP A 1 306 ? -13.120 -25.549 15.828  1.00 40.79  ? 306 ASP A OD1 1 
ATOM   2396  O  OD2 . ASP A 1 306 ? -12.390 -24.257 17.447  1.00 45.27  ? 306 ASP A OD2 1 
ATOM   2397  N  N   . TYR A 1 307 ? -13.608 -21.549 12.734  1.00 29.33  ? 307 TYR A N   1 
ATOM   2398  C  CA  . TYR A 1 307 ? -14.140 -20.465 11.916  1.00 31.69  ? 307 TYR A CA  1 
ATOM   2399  C  C   . TYR A 1 307 ? -15.113 -21.008 10.881  1.00 33.38  ? 307 TYR A C   1 
ATOM   2400  O  O   . TYR A 1 307 ? -16.235 -20.511 10.733  1.00 31.94  ? 307 TYR A O   1 
ATOM   2401  C  CB  . TYR A 1 307 ? -13.002 -19.728 11.218  1.00 30.60  ? 307 TYR A CB  1 
ATOM   2402  C  CG  . TYR A 1 307 ? -12.188 -18.810 12.095  1.00 34.01  ? 307 TYR A CG  1 
ATOM   2403  C  CD1 . TYR A 1 307 ? -12.774 -18.085 13.125  1.00 33.59  ? 307 TYR A CD1 1 
ATOM   2404  C  CD2 . TYR A 1 307 ? -10.826 -18.658 11.877  1.00 39.06  ? 307 TYR A CD2 1 
ATOM   2405  C  CE1 . TYR A 1 307 ? -12.022 -17.243 13.923  1.00 35.45  ? 307 TYR A CE1 1 
ATOM   2406  C  CE2 . TYR A 1 307 ? -10.066 -17.813 12.659  1.00 36.33  ? 307 TYR A CE2 1 
ATOM   2407  C  CZ  . TYR A 1 307 ? -10.661 -17.112 13.680  1.00 36.65  ? 307 TYR A CZ  1 
ATOM   2408  O  OH  . TYR A 1 307 ? -9.881  -16.279 14.450  1.00 42.45  ? 307 TYR A OH  1 
ATOM   2409  N  N   . ILE A 1 308 ? -14.687 -22.039 10.154  1.00 32.67  ? 308 ILE A N   1 
ATOM   2410  C  CA  . ILE A 1 308 ? -15.525 -22.618 9.111   1.00 35.57  ? 308 ILE A CA  1 
ATOM   2411  C  C   . ILE A 1 308 ? -16.757 -23.274 9.718   1.00 36.56  ? 308 ILE A C   1 
ATOM   2412  O  O   . ILE A 1 308 ? -17.858 -23.206 9.153   1.00 40.80  ? 308 ILE A O   1 
ATOM   2413  C  CB  . ILE A 1 308 ? -14.700 -23.601 8.264   1.00 33.42  ? 308 ILE A CB  1 
ATOM   2414  C  CG1 . ILE A 1 308 ? -13.852 -22.818 7.254   1.00 39.36  ? 308 ILE A CG1 1 
ATOM   2415  C  CG2 . ILE A 1 308 ? -15.615 -24.584 7.557   1.00 35.29  ? 308 ILE A CG2 1 
ATOM   2416  C  CD1 . ILE A 1 308 ? -12.523 -23.453 6.914   1.00 35.61  ? 308 ILE A CD1 1 
ATOM   2417  N  N   . ALA A 1 309 ? -16.600 -23.893 10.890  1.00 36.12  ? 309 ALA A N   1 
ATOM   2418  C  CA  . ALA A 1 309 ? -17.746 -24.455 11.587  1.00 34.87  ? 309 ALA A CA  1 
ATOM   2419  C  C   . ALA A 1 309 ? -18.777 -23.381 11.889  1.00 42.06  ? 309 ALA A C   1 
ATOM   2420  O  O   . ALA A 1 309 ? -19.988 -23.638 11.846  1.00 45.97  ? 309 ALA A O   1 
ATOM   2421  C  CB  . ALA A 1 309 ? -17.289 -25.129 12.879  1.00 37.57  ? 309 ALA A CB  1 
ATOM   2422  N  N   . LEU A 1 310 ? -18.318 -22.173 12.223  1.00 41.32  ? 310 LEU A N   1 
ATOM   2423  C  CA  . LEU A 1 310 ? -19.259 -21.083 12.456  1.00 43.58  ? 310 LEU A CA  1 
ATOM   2424  C  C   . LEU A 1 310 ? -20.065 -20.795 11.201  1.00 38.36  ? 310 LEU A C   1 
ATOM   2425  O  O   . LEU A 1 310 ? -21.277 -20.567 11.266  1.00 36.18  ? 310 LEU A O   1 
ATOM   2426  C  CB  . LEU A 1 310 ? -18.521 -19.824 12.921  1.00 42.24  ? 310 LEU A CB  1 
ATOM   2427  C  CG  . LEU A 1 310 ? -19.436 -18.721 13.466  1.00 42.77  ? 310 LEU A CG  1 
ATOM   2428  C  CD1 . LEU A 1 310 ? -18.765 -17.967 14.601  1.00 41.39  ? 310 LEU A CD1 1 
ATOM   2429  C  CD2 . LEU A 1 310 ? -19.882 -17.762 12.364  1.00 38.91  ? 310 LEU A CD2 1 
ATOM   2430  N  N   . ILE A 1 311 ? -19.399 -20.798 10.048  1.00 43.34  ? 311 ILE A N   1 
ATOM   2431  C  CA  . ILE A 1 311 ? -20.076 -20.508 8.790   1.00 41.20  ? 311 ILE A CA  1 
ATOM   2432  C  C   . ILE A 1 311 ? -21.161 -21.549 8.523   1.00 43.12  ? 311 ILE A C   1 
ATOM   2433  O  O   . ILE A 1 311 ? -22.299 -21.209 8.170   1.00 39.52  ? 311 ILE A O   1 
ATOM   2434  C  CB  . ILE A 1 311 ? -19.039 -20.427 7.657   1.00 33.72  ? 311 ILE A CB  1 
ATOM   2435  C  CG1 . ILE A 1 311 ? -18.012 -19.336 7.974   1.00 39.52  ? 311 ILE A CG1 1 
ATOM   2436  C  CG2 . ILE A 1 311 ? -19.710 -20.161 6.325   1.00 35.63  ? 311 ILE A CG2 1 
ATOM   2437  C  CD1 . ILE A 1 311 ? -16.861 -19.228 6.984   1.00 35.56  ? 311 ILE A CD1 1 
ATOM   2438  N  N   . ARG A 1 312 ? -20.840 -22.827 8.741   1.00 45.29  ? 312 ARG A N   1 
ATOM   2439  C  CA  . ARG A 1 312 ? -21.826 -23.891 8.571   1.00 43.86  ? 312 ARG A CA  1 
ATOM   2440  C  C   . ARG A 1 312 ? -22.979 -23.742 9.554   1.00 40.14  ? 312 ARG A C   1 
ATOM   2441  O  O   . ARG A 1 312 ? -24.152 -23.804 9.168   1.00 41.05  ? 312 ARG A O   1 
ATOM   2442  C  CB  . ARG A 1 312 ? -21.147 -25.250 8.726   1.00 44.09  ? 312 ARG A CB  1 
ATOM   2443  C  CG  . ARG A 1 312 ? -19.879 -25.346 7.906   1.00 46.33  ? 312 ARG A CG  1 
ATOM   2444  C  CD  . ARG A 1 312 ? -19.342 -26.755 7.788   1.00 52.31  ? 312 ARG A CD  1 
ATOM   2445  N  NE  . ARG A 1 312 ? -18.541 -26.889 6.579   1.00 56.47  ? 312 ARG A NE  1 
ATOM   2446  C  CZ  . ARG A 1 312 ? -17.637 -27.837 6.386   1.00 58.66  ? 312 ARG A CZ  1 
ATOM   2447  N  NH1 . ARG A 1 312 ? -17.389 -28.747 7.312   1.00 56.01  ? 312 ARG A NH1 1 
ATOM   2448  N  NH2 . ARG A 1 312 ? -16.949 -27.858 5.247   1.00 57.09  ? 312 ARG A NH2 1 
ATOM   2449  N  N   . ARG A 1 313 ? -22.667 -23.522 10.831  1.00 38.41  ? 313 ARG A N   1 
ATOM   2450  C  CA  . ARG A 1 313 ? -23.720 -23.542 11.839  1.00 45.11  ? 313 ARG A CA  1 
ATOM   2451  C  C   . ARG A 1 313 ? -24.660 -22.347 11.695  1.00 43.70  ? 313 ARG A C   1 
ATOM   2452  O  O   . ARG A 1 313 ? -25.882 -22.484 11.847  1.00 39.20  ? 313 ARG A O   1 
ATOM   2453  C  CB  . ARG A 1 313 ? -23.101 -23.595 13.236  1.00 43.26  ? 313 ARG A CB  1 
ATOM   2454  C  CG  . ARG A 1 313 ? -24.049 -23.197 14.369  1.00 40.28  ? 313 ARG A CG  1 
ATOM   2455  C  CD  . ARG A 1 313 ? -23.369 -23.288 15.737  1.00 44.58  ? 313 ARG A CD  1 
ATOM   2456  N  NE  . ARG A 1 313 ? -22.405 -22.214 15.970  1.00 45.61  ? 313 ARG A NE  1 
ATOM   2457  C  CZ  . ARG A 1 313 ? -21.096 -22.317 15.763  1.00 46.77  ? 313 ARG A CZ  1 
ATOM   2458  N  NH1 . ARG A 1 313 ? -20.556 -23.432 15.299  1.00 43.15  ? 313 ARG A NH1 1 
ATOM   2459  N  NH2 . ARG A 1 313 ? -20.311 -21.274 16.028  1.00 43.22  ? 313 ARG A NH2 1 
ATOM   2460  N  N   . THR A 1 314 ? -24.117 -21.169 11.396  1.00 40.72  ? 314 THR A N   1 
ATOM   2461  C  CA  . THR A 1 314 ? -24.956 -19.980 11.337  1.00 35.70  ? 314 THR A CA  1 
ATOM   2462  C  C   . THR A 1 314 ? -25.680 -19.856 10.005  1.00 37.73  ? 314 THR A C   1 
ATOM   2463  O  O   . THR A 1 314 ? -26.757 -19.253 9.943   1.00 40.01  ? 314 THR A O   1 
ATOM   2464  C  CB  . THR A 1 314 ? -24.103 -18.737 11.583  1.00 43.93  ? 314 THR A CB  1 
ATOM   2465  O  OG1 . THR A 1 314 ? -23.222 -18.533 10.464  1.00 39.72  ? 314 THR A OG1 1 
ATOM   2466  C  CG2 . THR A 1 314 ? -23.279 -18.918 12.841  1.00 40.22  ? 314 THR A CG2 1 
ATOM   2467  N  N   . GLY A 1 315 ? -25.109 -20.417 8.941   1.00 40.51  ? 315 GLY A N   1 
ATOM   2468  C  CA  . GLY A 1 315 ? -25.582 -20.177 7.599   1.00 39.05  ? 315 GLY A CA  1 
ATOM   2469  C  C   . GLY A 1 315 ? -25.162 -18.853 6.992   1.00 47.54  ? 315 GLY A C   1 
ATOM   2470  O  O   . GLY A 1 315 ? -25.484 -18.604 5.825   1.00 49.61  ? 315 GLY A O   1 
ATOM   2471  N  N   . THR A 1 316 ? -24.432 -18.014 7.724   1.00 43.65  ? 316 THR A N   1 
ATOM   2472  C  CA  . THR A 1 316 ? -24.167 -16.643 7.292   1.00 44.28  ? 316 THR A CA  1 
ATOM   2473  C  C   . THR A 1 316 ? -23.298 -16.572 6.036   1.00 37.74  ? 316 THR A C   1 
ATOM   2474  O  O   . THR A 1 316 ? -22.514 -17.472 5.726   1.00 39.09  ? 316 THR A O   1 
ATOM   2475  C  CB  . THR A 1 316 ? -23.485 -15.859 8.417   1.00 42.88  ? 316 THR A CB  1 
ATOM   2476  O  OG1 . THR A 1 316 ? -23.575 -14.449 8.162   1.00 41.29  ? 316 THR A OG1 1 
ATOM   2477  C  CG2 . THR A 1 316 ? -22.029 -16.261 8.518   1.00 41.85  ? 316 THR A CG2 1 
ATOM   2478  N  N   . LYS A 1 317 ? -23.445 -15.469 5.311   1.00 37.49  ? 317 LYS A N   1 
ATOM   2479  C  CA  . LYS A 1 317 ? -22.533 -15.114 4.234   1.00 40.66  ? 317 LYS A CA  1 
ATOM   2480  C  C   . LYS A 1 317 ? -21.774 -13.819 4.537   1.00 35.61  ? 317 LYS A C   1 
ATOM   2481  O  O   . LYS A 1 317 ? -21.117 -13.269 3.650   1.00 34.40  ? 317 LYS A O   1 
ATOM   2482  C  CB  . LYS A 1 317 ? -23.310 -15.017 2.914   1.00 43.38  ? 317 LYS A CB  1 
ATOM   2483  C  CG  . LYS A 1 317 ? -24.594 -14.207 3.050   1.00 48.08  ? 317 LYS A CG  1 
ATOM   2484  C  CD  . LYS A 1 317 ? -25.765 -14.824 2.313   1.00 56.68  ? 317 LYS A CD  1 
ATOM   2485  C  CE  . LYS A 1 317 ? -27.072 -14.108 2.669   1.00 52.08  ? 317 LYS A CE  1 
ATOM   2486  N  NZ  . LYS A 1 317 ? -27.702 -14.685 3.894   1.00 57.31  ? 317 LYS A NZ  1 
ATOM   2487  N  N   . HIS A 1 318 ? -21.847 -13.316 5.766   1.00 39.01  ? 318 HIS A N   1 
ATOM   2488  C  CA  . HIS A 1 318 ? -21.081 -12.149 6.190   1.00 37.41  ? 318 HIS A CA  1 
ATOM   2489  C  C   . HIS A 1 318 ? -20.008 -12.521 7.207   1.00 33.08  ? 318 HIS A C   1 
ATOM   2490  O  O   . HIS A 1 318 ? -19.688 -11.741 8.106   1.00 34.10  ? 318 HIS A O   1 
ATOM   2491  C  CB  . HIS A 1 318 ? -22.011 -11.083 6.755   1.00 35.80  ? 318 HIS A CB  1 
ATOM   2492  C  CG  . HIS A 1 318 ? -22.945 -10.521 5.738   1.00 38.47  ? 318 HIS A CG  1 
ATOM   2493  N  ND1 . HIS A 1 318 ? -24.225 -11.008 5.561   1.00 40.22  ? 318 HIS A ND1 1 
ATOM   2494  C  CD2 . HIS A 1 318 ? -22.787 -9.524  4.835   1.00 31.40  ? 318 HIS A CD2 1 
ATOM   2495  C  CE1 . HIS A 1 318 ? -24.816 -10.329 4.592   1.00 41.15  ? 318 HIS A CE1 1 
ATOM   2496  N  NE2 . HIS A 1 318 ? -23.966 -9.423  4.137   1.00 39.98  ? 318 HIS A NE2 1 
ATOM   2497  N  N   . PHE A 1 319 ? -19.478 -13.729 7.092   1.00 33.70  ? 319 PHE A N   1 
ATOM   2498  C  CA  . PHE A 1 319 ? -18.348 -14.183 7.880   1.00 32.32  ? 319 PHE A CA  1 
ATOM   2499  C  C   . PHE A 1 319 ? -17.493 -15.038 6.973   1.00 34.50  ? 319 PHE A C   1 
ATOM   2500  O  O   . PHE A 1 319 ? -18.003 -15.934 6.298   1.00 35.11  ? 319 PHE A O   1 
ATOM   2501  C  CB  . PHE A 1 319 ? -18.766 -14.975 9.118   1.00 34.56  ? 319 PHE A CB  1 
ATOM   2502  C  CG  . PHE A 1 319 ? -17.613 -15.353 10.007  1.00 37.12  ? 319 PHE A CG  1 
ATOM   2503  C  CD1 . PHE A 1 319 ? -17.073 -14.427 10.891  1.00 31.15  ? 319 PHE A CD1 1 
ATOM   2504  C  CD2 . PHE A 1 319 ? -17.084 -16.632 9.978   1.00 33.60  ? 319 PHE A CD2 1 
ATOM   2505  C  CE1 . PHE A 1 319 ? -16.023 -14.766 11.717  1.00 31.96  ? 319 PHE A CE1 1 
ATOM   2506  C  CE2 . PHE A 1 319 ? -16.030 -16.981 10.793  1.00 34.50  ? 319 PHE A CE2 1 
ATOM   2507  C  CZ  . PHE A 1 319 ? -15.495 -16.043 11.671  1.00 35.95  ? 319 PHE A CZ  1 
ATOM   2508  N  N   . GLY A 1 320 ? -16.203 -14.733 6.939   1.00 34.05  ? 320 GLY A N   1 
ATOM   2509  C  CA  . GLY A 1 320 ? -15.302 -15.344 5.994   1.00 29.00  ? 320 GLY A CA  1 
ATOM   2510  C  C   . GLY A 1 320 ? -13.925 -15.367 6.603   1.00 29.10  ? 320 GLY A C   1 
ATOM   2511  O  O   . GLY A 1 320 ? -13.718 -14.964 7.747   1.00 33.30  ? 320 GLY A O   1 
ATOM   2512  N  N   . LEU A 1 321 ? -12.992 -15.880 5.838   1.00 25.65  ? 321 LEU A N   1 
ATOM   2513  C  CA  . LEU A 1 321 ? -11.616 -15.979 6.246   1.00 28.24  ? 321 LEU A CA  1 
ATOM   2514  C  C   . LEU A 1 321 ? -10.841 -14.882 5.540   1.00 31.71  ? 321 LEU A C   1 
ATOM   2515  O  O   . LEU A 1 321 ? -11.117 -14.574 4.383   1.00 28.76  ? 321 LEU A O   1 
ATOM   2516  C  CB  . LEU A 1 321 ? -11.047 -17.345 5.883   1.00 32.77  ? 321 LEU A CB  1 
ATOM   2517  C  CG  . LEU A 1 321 ? -11.796 -18.512 6.520   1.00 33.31  ? 321 LEU A CG  1 
ATOM   2518  C  CD1 . LEU A 1 321 ? -11.103 -19.810 6.176   1.00 38.70  ? 321 LEU A CD1 1 
ATOM   2519  C  CD2 . LEU A 1 321 ? -11.819 -18.320 7.997   1.00 30.79  ? 321 LEU A CD2 1 
ATOM   2520  N  N   . LEU A 1 322 ? -9.903  -14.273 6.255   1.00 31.74  ? 322 LEU A N   1 
ATOM   2521  C  CA  . LEU A 1 322 ? -8.885  -13.411 5.670   1.00 26.83  ? 322 LEU A CA  1 
ATOM   2522  C  C   . LEU A 1 322 ? -7.563  -14.151 5.788   1.00 28.34  ? 322 LEU A C   1 
ATOM   2523  O  O   . LEU A 1 322 ? -7.155  -14.520 6.895   1.00 29.88  ? 322 LEU A O   1 
ATOM   2524  C  CB  . LEU A 1 322 ? -8.828  -12.057 6.392   1.00 25.71  ? 322 LEU A CB  1 
ATOM   2525  C  CG  . LEU A 1 322 ? -7.910  -10.929 5.887   1.00 26.85  ? 322 LEU A CG  1 
ATOM   2526  C  CD1 . LEU A 1 322 ? -8.437  -9.547  6.302   1.00 28.23  ? 322 LEU A CD1 1 
ATOM   2527  C  CD2 . LEU A 1 322 ? -6.497  -11.092 6.404   1.00 25.54  ? 322 LEU A CD2 1 
ATOM   2528  N  N   . LEU A 1 323 ? -6.913  -14.395 4.664   1.00 23.98  ? 323 LEU A N   1 
ATOM   2529  C  CA  . LEU A 1 323 ? -5.608  -15.039 4.673   1.00 28.51  ? 323 LEU A CA  1 
ATOM   2530  C  C   . LEU A 1 323 ? -4.482  -14.008 4.679   1.00 32.58  ? 323 LEU A C   1 
ATOM   2531  O  O   . LEU A 1 323 ? -4.524  -13.022 3.938   1.00 26.65  ? 323 LEU A O   1 
ATOM   2532  C  CB  . LEU A 1 323 ? -5.442  -15.947 3.451   1.00 30.89  ? 323 LEU A CB  1 
ATOM   2533  C  CG  . LEU A 1 323 ? -5.711  -17.448 3.525   1.00 36.44  ? 323 LEU A CG  1 
ATOM   2534  C  CD1 . LEU A 1 323 ? -6.920  -17.776 4.387   1.00 39.05  ? 323 LEU A CD1 1 
ATOM   2535  C  CD2 . LEU A 1 323 ? -5.844  -18.025 2.103   1.00 37.20  ? 323 LEU A CD2 1 
ATOM   2536  N  N   . ASP A 1 324 ? -3.446  -14.271 5.483   1.00 33.08  ? 324 ASP A N   1 
ATOM   2537  C  CA  . ASP A 1 324 ? -2.189  -13.522 5.444   1.00 30.62  ? 324 ASP A CA  1 
ATOM   2538  C  C   . ASP A 1 324 ? -1.142  -14.397 4.764   1.00 29.23  ? 324 ASP A C   1 
ATOM   2539  O  O   . ASP A 1 324 ? -0.839  -15.492 5.256   1.00 31.55  ? 324 ASP A O   1 
ATOM   2540  C  CB  . ASP A 1 324 ? -1.753  -13.121 6.862   1.00 31.26  ? 324 ASP A CB  1 
ATOM   2541  C  CG  . ASP A 1 324 ? -0.587  -12.115 6.881   1.00 27.90  ? 324 ASP A CG  1 
ATOM   2542  O  OD1 . ASP A 1 324 ? 0.558   -12.544 6.670   1.00 28.79  ? 324 ASP A OD1 1 
ATOM   2543  O  OD2 . ASP A 1 324 ? -0.824  -10.900 7.122   1.00 25.19  ? 324 ASP A OD2 1 
ATOM   2544  N  N   . THR A 1 325 ? -0.579  -13.915 3.651   1.00 27.47  ? 325 THR A N   1 
ATOM   2545  C  CA  . THR A 1 325 ? 0.319   -14.761 2.865   1.00 24.21  ? 325 THR A CA  1 
ATOM   2546  C  C   . THR A 1 325 ? 1.660   -15.007 3.539   1.00 25.47  ? 325 THR A C   1 
ATOM   2547  O  O   . THR A 1 325 ? 2.504   -15.675 2.941   1.00 28.30  ? 325 THR A O   1 
ATOM   2548  C  CB  . THR A 1 325 ? 0.552   -14.197 1.452   1.00 30.03  ? 325 THR A CB  1 
ATOM   2549  O  OG1 . THR A 1 325 ? 1.355   -13.007 1.498   1.00 30.36  ? 325 THR A OG1 1 
ATOM   2550  C  CG2 . THR A 1 325 ? -0.780  -13.895 0.757   1.00 29.08  ? 325 THR A CG2 1 
ATOM   2551  N  N   . GLY A 1 326 ? 1.877   -14.524 4.765   1.00 28.68  ? 326 GLY A N   1 
ATOM   2552  C  CA  . GLY A 1 326 ? 3.013   -15.014 5.545   1.00 28.01  ? 326 GLY A CA  1 
ATOM   2553  C  C   . GLY A 1 326 ? 2.880   -16.462 6.023   1.00 26.18  ? 326 GLY A C   1 
ATOM   2554  O  O   . GLY A 1 326 ? 3.877   -17.057 6.442   1.00 30.42  ? 326 GLY A O   1 
ATOM   2555  N  N   . ILE A 1 327 ? 1.680   -17.040 5.980   1.00 28.78  ? 327 ILE A N   1 
ATOM   2556  C  CA  . ILE A 1 327 ? 1.565   -18.473 6.244   1.00 28.10  ? 327 ILE A CA  1 
ATOM   2557  C  C   . ILE A 1 327 ? 2.299   -19.270 5.168   1.00 31.63  ? 327 ILE A C   1 
ATOM   2558  O  O   . ILE A 1 327 ? 2.723   -20.404 5.407   1.00 33.70  ? 327 ILE A O   1 
ATOM   2559  C  CB  . ILE A 1 327 ? 0.088   -18.896 6.343   1.00 28.98  ? 327 ILE A CB  1 
ATOM   2560  C  CG1 . ILE A 1 327 ? -0.628  -18.660 5.024   1.00 28.98  ? 327 ILE A CG1 1 
ATOM   2561  C  CG2 . ILE A 1 327 ? -0.623  -18.155 7.439   1.00 31.20  ? 327 ILE A CG2 1 
ATOM   2562  C  CD1 . ILE A 1 327 ? -2.087  -19.001 5.081   1.00 35.22  ? 327 ILE A CD1 1 
ATOM   2563  N  N   . PHE A 1 328 ? 2.480   -18.694 3.982   1.00 27.28  ? 328 PHE A N   1 
ATOM   2564  C  CA  . PHE A 1 328 ? 3.164   -19.375 2.889   1.00 31.35  ? 328 PHE A CA  1 
ATOM   2565  C  C   . PHE A 1 328 ? 4.662   -19.120 2.887   1.00 28.92  ? 328 PHE A C   1 
ATOM   2566  O  O   . PHE A 1 328 ? 5.361   -19.659 2.024   1.00 29.30  ? 328 PHE A O   1 
ATOM   2567  C  CB  . PHE A 1 328 ? 2.582   -18.951 1.529   1.00 26.46  ? 328 PHE A CB  1 
ATOM   2568  C  CG  . PHE A 1 328 ? 1.079   -19.116 1.427   1.00 31.22  ? 328 PHE A CG  1 
ATOM   2569  C  CD1 . PHE A 1 328 ? 0.480   -20.343 1.664   1.00 32.14  ? 328 PHE A CD1 1 
ATOM   2570  C  CD2 . PHE A 1 328 ? 0.264   -18.033 1.114   1.00 26.55  ? 328 PHE A CD2 1 
ATOM   2571  C  CE1 . PHE A 1 328 ? -0.909  -20.498 1.576   1.00 32.12  ? 328 PHE A CE1 1 
ATOM   2572  C  CE2 . PHE A 1 328 ? -1.105  -18.175 1.026   1.00 26.44  ? 328 PHE A CE2 1 
ATOM   2573  C  CZ  . PHE A 1 328 ? -1.701  -19.418 1.258   1.00 27.36  ? 328 PHE A CZ  1 
ATOM   2574  N  N   . GLN A 1 329 ? 5.166   -18.309 3.816   1.00 26.65  ? 329 GLN A N   1 
ATOM   2575  C  CA  . GLN A 1 329 ? 6.586   -17.969 3.840   1.00 27.59  ? 329 GLN A CA  1 
ATOM   2576  C  C   . GLN A 1 329 ? 7.424   -19.240 3.850   1.00 36.69  ? 329 GLN A C   1 
ATOM   2577  O  O   . GLN A 1 329 ? 7.177   -20.151 4.646   1.00 37.19  ? 329 GLN A O   1 
ATOM   2578  C  CB  . GLN A 1 329 ? 6.886   -17.123 5.079   1.00 33.84  ? 329 GLN A CB  1 
ATOM   2579  C  CG  . GLN A 1 329 ? 8.360   -16.734 5.257   1.00 37.15  ? 329 GLN A CG  1 
ATOM   2580  C  CD  . GLN A 1 329 ? 8.689   -16.168 6.645   1.00 32.86  ? 329 GLN A CD  1 
ATOM   2581  O  OE1 . GLN A 1 329 ? 7.803   -15.743 7.401   1.00 27.38  ? 329 GLN A OE1 1 
ATOM   2582  N  NE2 . GLN A 1 329 ? 9.972   -16.152 6.974   1.00 34.77  ? 329 GLN A NE2 1 
ATOM   2583  N  N   . ASP A 1 330 ? 8.400   -19.315 2.947   1.00 33.50  ? 330 ASP A N   1 
ATOM   2584  C  CA  . ASP A 1 330 ? 9.227   -20.513 2.824   1.00 36.34  ? 330 ASP A CA  1 
ATOM   2585  C  C   . ASP A 1 330 ? 10.715  -20.235 3.015   1.00 40.89  ? 330 ASP A C   1 
ATOM   2586  O  O   . ASP A 1 330 ? 11.547  -21.067 2.637   1.00 40.81  ? 330 ASP A O   1 
ATOM   2587  C  CB  . ASP A 1 330 ? 8.985   -21.211 1.483   1.00 35.02  ? 330 ASP A CB  1 
ATOM   2588  C  CG  . ASP A 1 330 ? 9.667   -20.508 0.291   1.00 37.11  ? 330 ASP A CG  1 
ATOM   2589  O  OD1 . ASP A 1 330 ? 10.182  -19.371 0.409   1.00 41.76  ? 330 ASP A OD1 1 
ATOM   2590  O  OD2 . ASP A 1 330 ? 9.675   -21.115 -0.794  1.00 36.54  ? 330 ASP A OD2 1 
ATOM   2591  N  N   . ARG A 1 331 ? 11.070  -19.087 3.588   1.00 38.34  ? 331 ARG A N   1 
ATOM   2592  C  CA  . ARG A 1 331 ? 12.459  -18.684 3.775   1.00 34.29  ? 331 ARG A CA  1 
ATOM   2593  C  C   . ARG A 1 331 ? 12.514  -17.743 4.965   1.00 36.38  ? 331 ARG A C   1 
ATOM   2594  O  O   . ARG A 1 331 ? 11.562  -16.993 5.201   1.00 37.23  ? 331 ARG A O   1 
ATOM   2595  C  CB  . ARG A 1 331 ? 13.040  -18.005 2.524   1.00 33.95  ? 331 ARG A CB  1 
ATOM   2596  C  CG  . ARG A 1 331 ? 13.641  -18.977 1.505   1.00 37.47  ? 331 ARG A CG  1 
ATOM   2597  C  CD  . ARG A 1 331 ? 13.632  -18.409 0.098   1.00 36.33  ? 331 ARG A CD  1 
ATOM   2598  N  NE  . ARG A 1 331 ? 12.288  -18.044 -0.330  1.00 32.61  ? 331 ARG A NE  1 
ATOM   2599  C  CZ  . ARG A 1 331 ? 12.021  -17.079 -1.201  1.00 29.33  ? 331 ARG A CZ  1 
ATOM   2600  N  NH1 . ARG A 1 331 ? 12.988  -16.415 -1.814  1.00 32.01  ? 331 ARG A NH1 1 
ATOM   2601  N  NH2 . ARG A 1 331 ? 10.755  -16.776 -1.459  1.00 33.19  ? 331 ARG A NH2 1 
ATOM   2602  N  N   . PRO A 1 332 ? 13.588  -17.771 5.741   1.00 39.22  ? 332 PRO A N   1 
ATOM   2603  C  CA  . PRO A 1 332 ? 13.564  -17.089 7.041   1.00 37.95  ? 332 PRO A CA  1 
ATOM   2604  C  C   . PRO A 1 332 ? 13.688  -15.579 6.935   1.00 40.44  ? 332 PRO A C   1 
ATOM   2605  O  O   . PRO A 1 332 ? 14.457  -15.044 6.132   1.00 44.55  ? 332 PRO A O   1 
ATOM   2606  C  CB  . PRO A 1 332 ? 14.770  -17.687 7.777   1.00 41.06  ? 332 PRO A CB  1 
ATOM   2607  C  CG  . PRO A 1 332 ? 15.683  -18.165 6.691   1.00 44.99  ? 332 PRO A CG  1 
ATOM   2608  C  CD  . PRO A 1 332 ? 14.795  -18.598 5.558   1.00 40.49  ? 332 PRO A CD  1 
ATOM   2609  N  N   . ILE A 1 333 ? 12.904  -14.897 7.763   1.00 40.49  ? 333 ILE A N   1 
ATOM   2610  C  CA  . ILE A 1 333 ? 13.137  -13.480 8.028   1.00 33.60  ? 333 ILE A CA  1 
ATOM   2611  C  C   . ILE A 1 333 ? 14.542  -13.321 8.588   1.00 42.93  ? 333 ILE A C   1 
ATOM   2612  O  O   . ILE A 1 333 ? 14.937  -14.086 9.490   1.00 44.50  ? 333 ILE A O   1 
ATOM   2613  C  CB  . ILE A 1 333 ? 12.076  -12.954 9.001   1.00 39.55  ? 333 ILE A CB  1 
ATOM   2614  C  CG1 . ILE A 1 333 ? 10.703  -13.012 8.333   1.00 35.65  ? 333 ILE A CG1 1 
ATOM   2615  C  CG2 . ILE A 1 333 ? 12.388  -11.543 9.489   1.00 37.61  ? 333 ILE A CG2 1 
ATOM   2616  C  CD1 . ILE A 1 333 ? 9.548   -12.827 9.295   1.00 35.67  ? 333 ILE A CD1 1 
ATOM   2617  N  N   . PRO A 1 334 ? 15.348  -12.379 8.096   1.00 39.06  ? 334 PRO A N   1 
ATOM   2618  C  CA  . PRO A 1 334 ? 16.761  -12.367 8.474   1.00 42.06  ? 334 PRO A CA  1 
ATOM   2619  C  C   . PRO A 1 334 ? 16.935  -12.124 9.963   1.00 49.12  ? 334 PRO A C   1 
ATOM   2620  O  O   . PRO A 1 334 ? 16.082  -11.526 10.625  1.00 47.00  ? 334 PRO A O   1 
ATOM   2621  C  CB  . PRO A 1 334 ? 17.342  -11.209 7.648   1.00 43.85  ? 334 PRO A CB  1 
ATOM   2622  C  CG  . PRO A 1 334 ? 16.340  -10.978 6.544   1.00 37.50  ? 334 PRO A CG  1 
ATOM   2623  C  CD  . PRO A 1 334 ? 15.026  -11.272 7.173   1.00 40.99  ? 334 PRO A CD  1 
ATOM   2624  N  N   . LEU A 1 335 ? 18.056  -12.616 10.486  1.00 54.01  ? 335 LEU A N   1 
ATOM   2625  C  CA  . LEU A 1 335 ? 18.504  -12.250 11.821  1.00 62.10  ? 335 LEU A CA  1 
ATOM   2626  C  C   . LEU A 1 335 ? 19.067  -10.838 11.806  1.00 65.09  ? 335 LEU A C   1 
ATOM   2627  O  O   . LEU A 1 335 ? 19.751  -10.440 10.858  1.00 62.17  ? 335 LEU A O   1 
ATOM   2628  C  CB  . LEU A 1 335 ? 19.584  -13.214 12.307  1.00 61.39  ? 335 LEU A CB  1 
ATOM   2629  C  CG  . LEU A 1 335 ? 19.402  -14.684 11.946  1.00 62.71  ? 335 LEU A CG  1 
ATOM   2630  C  CD1 . LEU A 1 335 ? 20.753  -15.374 11.906  1.00 60.83  ? 335 LEU A CD1 1 
ATOM   2631  C  CD2 . LEU A 1 335 ? 18.469  -15.360 12.953  1.00 60.35  ? 335 LEU A CD2 1 
ATOM   2632  N  N   . LYS A 1 336 ? 18.790  -10.083 12.865  1.00 69.91  ? 336 LYS A N   1 
ATOM   2633  C  CA  . LYS A 1 336 ? 19.437  -8.790  13.016  1.00 78.71  ? 336 LYS A CA  1 
ATOM   2634  C  C   . LYS A 1 336 ? 20.829  -8.972  13.620  1.00 80.52  ? 336 LYS A C   1 
ATOM   2635  O  O   . LYS A 1 336 ? 21.144  -10.030 14.180  1.00 71.08  ? 336 LYS A O   1 
ATOM   2636  C  CB  . LYS A 1 336 ? 18.588  -7.864  13.887  1.00 77.51  ? 336 LYS A CB  1 
ATOM   2637  C  CG  . LYS A 1 336 ? 17.283  -7.410  13.245  1.00 78.06  ? 336 LYS A CG  1 
ATOM   2638  C  CD  . LYS A 1 336 ? 16.322  -6.842  14.289  1.00 77.92  ? 336 LYS A CD  1 
ATOM   2639  C  CE  . LYS A 1 336 ? 14.957  -7.524  14.245  1.00 72.32  ? 336 LYS A CE  1 
ATOM   2640  N  NZ  . LYS A 1 336 ? 13.895  -6.590  13.772  1.00 62.93  ? 336 LYS A NZ  1 
ATOM   2641  N  N   . PRO A 1 337 ? 21.700  -7.968  13.484  1.00 85.45  ? 337 PRO A N   1 
ATOM   2642  C  CA  . PRO A 1 337 ? 23.010  -8.050  14.140  1.00 87.55  ? 337 PRO A CA  1 
ATOM   2643  C  C   . PRO A 1 337 ? 22.863  -8.140  15.652  1.00 86.73  ? 337 PRO A C   1 
ATOM   2644  O  O   . PRO A 1 337 ? 22.050  -7.442  16.264  1.00 84.57  ? 337 PRO A O   1 
ATOM   2645  C  CB  . PRO A 1 337 ? 23.707  -6.752  13.712  1.00 84.03  ? 337 PRO A CB  1 
ATOM   2646  C  CG  . PRO A 1 337 ? 22.608  -5.851  13.249  1.00 85.50  ? 337 PRO A CG  1 
ATOM   2647  C  CD  . PRO A 1 337 ? 21.593  -6.764  12.642  1.00 84.40  ? 337 PRO A CD  1 
ATOM   2648  N  N   . GLY A 1 338 ? 23.661  -9.023  16.253  1.00 80.16  ? 338 GLY A N   1 
ATOM   2649  C  CA  . GLY A 1 338 ? 23.636  -9.265  17.670  1.00 84.46  ? 338 GLY A CA  1 
ATOM   2650  C  C   . GLY A 1 338 ? 22.797  -10.459 18.073  1.00 84.18  ? 338 GLY A C   1 
ATOM   2651  O  O   . GLY A 1 338 ? 23.112  -11.116 19.072  1.00 86.53  ? 338 GLY A O   1 
ATOM   2652  N  N   . GLU A 1 339 ? 21.733  -10.748 17.329  1.00 83.08  ? 339 GLU A N   1 
ATOM   2653  C  CA  . GLU A 1 339 ? 20.945  -11.936 17.606  1.00 78.78  ? 339 GLU A CA  1 
ATOM   2654  C  C   . GLU A 1 339 ? 21.692  -13.179 17.138  1.00 80.74  ? 339 GLU A C   1 
ATOM   2655  O  O   . GLU A 1 339 ? 22.610  -13.120 16.313  1.00 83.14  ? 339 GLU A O   1 
ATOM   2656  C  CB  . GLU A 1 339 ? 19.570  -11.863 16.932  1.00 80.48  ? 339 GLU A CB  1 
ATOM   2657  C  CG  . GLU A 1 339 ? 19.083  -10.454 16.591  1.00 81.85  ? 339 GLU A CG  1 
ATOM   2658  C  CD  . GLU A 1 339 ? 17.730  -10.451 15.883  1.00 79.75  ? 339 GLU A CD  1 
ATOM   2659  O  OE1 . GLU A 1 339 ? 17.417  -11.441 15.179  1.00 73.91  ? 339 GLU A OE1 1 
ATOM   2660  O  OE2 . GLU A 1 339 ? 16.984  -9.454  16.034  1.00 78.53  ? 339 GLU A OE2 1 
ATOM   2661  N  N   . LEU A 1 340 ? 21.285  -14.315 17.682  1.00 74.81  ? 340 LEU A N   1 
ATOM   2662  C  CA  . LEU A 1 340 ? 21.922  -15.599 17.455  1.00 71.55  ? 340 LEU A CA  1 
ATOM   2663  C  C   . LEU A 1 340 ? 20.823  -16.636 17.308  1.00 71.13  ? 340 LEU A C   1 
ATOM   2664  O  O   . LEU A 1 340 ? 19.666  -16.364 17.644  1.00 73.08  ? 340 LEU A O   1 
ATOM   2665  C  CB  . LEU A 1 340 ? 22.860  -15.958 18.616  1.00 73.88  ? 340 LEU A CB  1 
ATOM   2666  C  CG  . LEU A 1 340 ? 24.254  -15.324 18.556  1.00 78.53  ? 340 LEU A CG  1 
ATOM   2667  C  CD1 . LEU A 1 340 ? 24.323  -14.007 19.336  1.00 76.26  ? 340 LEU A CD1 1 
ATOM   2668  C  CD2 . LEU A 1 340 ? 25.300  -16.309 19.058  1.00 80.52  ? 340 LEU A CD2 1 
ATOM   2669  N  N   . PRO A 1 341 ? 21.142  -17.823 16.788  1.00 71.67  ? 341 PRO A N   1 
ATOM   2670  C  CA  . PRO A 1 341 ? 20.110  -18.857 16.628  1.00 71.69  ? 341 PRO A CA  1 
ATOM   2671  C  C   . PRO A 1 341 ? 19.358  -19.143 17.923  1.00 67.17  ? 341 PRO A C   1 
ATOM   2672  O  O   . PRO A 1 341 ? 19.882  -18.963 19.026  1.00 66.63  ? 341 PRO A O   1 
ATOM   2673  C  CB  . PRO A 1 341 ? 20.909  -20.079 16.161  1.00 68.41  ? 341 PRO A CB  1 
ATOM   2674  C  CG  . PRO A 1 341 ? 22.054  -19.488 15.409  1.00 68.93  ? 341 PRO A CG  1 
ATOM   2675  C  CD  . PRO A 1 341 ? 22.402  -18.201 16.117  1.00 71.03  ? 341 PRO A CD  1 
ATOM   2676  N  N   . GLY A 1 342 ? 18.101  -19.567 17.769  1.00 64.10  ? 342 GLY A N   1 
ATOM   2677  C  CA  . GLY A 1 342 ? 17.261  -20.003 18.868  1.00 59.64  ? 342 GLY A CA  1 
ATOM   2678  C  C   . GLY A 1 342 ? 16.674  -18.909 19.737  1.00 62.85  ? 342 GLY A C   1 
ATOM   2679  O  O   . GLY A 1 342 ? 15.926  -19.229 20.676  1.00 57.78  ? 342 GLY A O   1 
ATOM   2680  N  N   . GLN A 1 343 ? 16.981  -17.638 19.464  1.00 57.70  ? 343 GLN A N   1 
ATOM   2681  C  CA  . GLN A 1 343 ? 16.523  -16.509 20.270  1.00 57.66  ? 343 GLN A CA  1 
ATOM   2682  C  C   . GLN A 1 343 ? 15.176  -15.946 19.812  1.00 55.07  ? 343 GLN A C   1 
ATOM   2683  O  O   . GLN A 1 343 ? 14.782  -14.871 20.280  1.00 52.59  ? 343 GLN A O   1 
ATOM   2684  C  CB  . GLN A 1 343 ? 17.559  -15.377 20.245  1.00 58.56  ? 343 GLN A CB  1 
ATOM   2685  C  CG  . GLN A 1 343 ? 18.921  -15.689 20.842  1.00 65.60  ? 343 GLN A CG  1 
ATOM   2686  C  CD  . GLN A 1 343 ? 19.686  -14.421 21.223  1.00 66.55  ? 343 GLN A CD  1 
ATOM   2687  O  OE1 . GLN A 1 343 ? 20.912  -14.370 21.133  1.00 66.44  ? 343 GLN A OE1 1 
ATOM   2688  N  NE2 . GLN A 1 343 ? 18.959  -13.396 21.654  1.00 62.48  ? 343 GLN A NE2 1 
ATOM   2689  N  N   . ARG A 1 344 ? 14.469  -16.629 18.914  1.00 51.95  ? 344 ARG A N   1 
ATOM   2690  C  CA  . ARG A 1 344 ? 13.233  -16.094 18.360  1.00 45.57  ? 344 ARG A CA  1 
ATOM   2691  C  C   . ARG A 1 344 ? 12.276  -17.241 18.072  1.00 42.89  ? 344 ARG A C   1 
ATOM   2692  O  O   . ARG A 1 344 ? 12.704  -18.389 17.897  1.00 37.46  ? 344 ARG A O   1 
ATOM   2693  C  CB  . ARG A 1 344 ? 13.498  -15.289 17.081  1.00 44.90  ? 344 ARG A CB  1 
ATOM   2694  C  CG  . ARG A 1 344 ? 13.706  -16.131 15.833  1.00 45.32  ? 344 ARG A CG  1 
ATOM   2695  C  CD  . ARG A 1 344 ? 14.101  -15.267 14.648  1.00 43.76  ? 344 ARG A CD  1 
ATOM   2696  N  NE  . ARG A 1 344 ? 14.327  -16.068 13.454  1.00 44.94  ? 344 ARG A NE  1 
ATOM   2697  C  CZ  . ARG A 1 344 ? 14.514  -15.562 12.242  1.00 40.69  ? 344 ARG A CZ  1 
ATOM   2698  N  NH1 . ARG A 1 344 ? 14.566  -14.260 12.044  1.00 39.80  ? 344 ARG A NH1 1 
ATOM   2699  N  NH2 . ARG A 1 344 ? 14.655  -16.386 11.207  1.00 38.91  ? 344 ARG A NH2 1 
ATOM   2700  N  N   . PRO A 1 345 ? 10.977  -16.964 17.998  1.00 37.08  ? 345 PRO A N   1 
ATOM   2701  C  CA  . PRO A 1 345 ? 10.015  -18.042 17.748  1.00 40.55  ? 345 PRO A CA  1 
ATOM   2702  C  C   . PRO A 1 345 ? 10.254  -18.728 16.408  1.00 45.49  ? 345 PRO A C   1 
ATOM   2703  O  O   . PRO A 1 345 ? 10.743  -18.125 15.450  1.00 45.80  ? 345 PRO A O   1 
ATOM   2704  C  CB  . PRO A 1 345 ? 8.667   -17.319 17.785  1.00 48.67  ? 345 PRO A CB  1 
ATOM   2705  C  CG  . PRO A 1 345 ? 8.900   -16.143 18.724  1.00 43.21  ? 345 PRO A CG  1 
ATOM   2706  C  CD  . PRO A 1 345 ? 10.324  -15.722 18.460  1.00 41.16  ? 345 PRO A CD  1 
ATOM   2707  N  N   . ALA A 1 346 ? 9.910   -20.019 16.362  1.00 41.41  ? 346 ALA A N   1 
ATOM   2708  C  CA  . ALA A 1 346 ? 10.193  -20.840 15.187  1.00 45.19  ? 346 ALA A CA  1 
ATOM   2709  C  C   . ALA A 1 346 ? 9.597   -20.235 13.919  1.00 44.41  ? 346 ALA A C   1 
ATOM   2710  O  O   . ALA A 1 346 ? 10.275  -20.123 12.890  1.00 43.98  ? 346 ALA A O   1 
ATOM   2711  C  CB  . ALA A 1 346 ? 9.657   -22.260 15.406  1.00 41.89  ? 346 ALA A CB  1 
ATOM   2712  N  N   . PHE A 1 347 ? 8.331   -19.818 13.981  1.00 39.06  ? 347 PHE A N   1 
ATOM   2713  C  CA  . PHE A 1 347 ? 7.606   -19.444 12.774  1.00 42.88  ? 347 PHE A CA  1 
ATOM   2714  C  C   . PHE A 1 347 ? 8.232   -18.264 12.036  1.00 42.35  ? 347 PHE A C   1 
ATOM   2715  O  O   . PHE A 1 347 ? 7.859   -18.014 10.883  1.00 40.23  ? 347 PHE A O   1 
ATOM   2716  C  CB  . PHE A 1 347 ? 6.149   -19.132 13.116  1.00 42.61  ? 347 PHE A CB  1 
ATOM   2717  C  CG  . PHE A 1 347 ? 5.964   -17.859 13.898  1.00 42.85  ? 347 PHE A CG  1 
ATOM   2718  C  CD1 . PHE A 1 347 ? 6.068   -17.852 15.280  1.00 44.19  ? 347 PHE A CD1 1 
ATOM   2719  C  CD2 . PHE A 1 347 ? 5.677   -16.673 13.253  1.00 40.06  ? 347 PHE A CD2 1 
ATOM   2720  C  CE1 . PHE A 1 347 ? 5.891   -16.675 15.992  1.00 40.62  ? 347 PHE A CE1 1 
ATOM   2721  C  CE2 . PHE A 1 347 ? 5.502   -15.503 13.963  1.00 35.37  ? 347 PHE A CE2 1 
ATOM   2722  C  CZ  . PHE A 1 347 ? 5.615   -15.504 15.324  1.00 40.49  ? 347 PHE A CZ  1 
ATOM   2723  N  N   . LEU A 1 348 ? 9.175   -17.542 12.646  1.00 38.00  ? 348 LEU A N   1 
ATOM   2724  C  CA  . LEU A 1 348 ? 9.768   -16.427 11.922  1.00 38.88  ? 348 LEU A CA  1 
ATOM   2725  C  C   . LEU A 1 348 ? 10.698  -16.907 10.827  1.00 41.69  ? 348 LEU A C   1 
ATOM   2726  O  O   . LEU A 1 348 ? 11.166  -16.088 10.030  1.00 40.90  ? 348 LEU A O   1 
ATOM   2727  C  CB  . LEU A 1 348 ? 10.512  -15.481 12.874  1.00 40.35  ? 348 LEU A CB  1 
ATOM   2728  C  CG  . LEU A 1 348 ? 9.569   -14.629 13.732  1.00 40.80  ? 348 LEU A CG  1 
ATOM   2729  C  CD1 . LEU A 1 348 ? 10.304  -13.915 14.859  1.00 48.01  ? 348 LEU A CD1 1 
ATOM   2730  C  CD2 . LEU A 1 348 ? 8.822   -13.635 12.871  1.00 35.76  ? 348 LEU A CD2 1 
ATOM   2731  N  N   . ASP A 1 349 ? 10.967  -18.209 10.764  1.00 40.76  ? 349 ASP A N   1 
ATOM   2732  C  CA  . ASP A 1 349 ? 11.736  -18.780 9.667   1.00 38.80  ? 349 ASP A CA  1 
ATOM   2733  C  C   . ASP A 1 349 ? 10.864  -19.256 8.517   1.00 32.52  ? 349 ASP A C   1 
ATOM   2734  O  O   . ASP A 1 349 ? 11.397  -19.645 7.471   1.00 33.16  ? 349 ASP A O   1 
ATOM   2735  C  CB  . ASP A 1 349 ? 12.597  -19.920 10.197  1.00 42.68  ? 349 ASP A CB  1 
ATOM   2736  C  CG  . ASP A 1 349 ? 13.370  -19.510 11.425  1.00 47.99  ? 349 ASP A CG  1 
ATOM   2737  O  OD1 . ASP A 1 349 ? 12.935  -19.857 12.546  1.00 55.57  ? 349 ASP A OD1 1 
ATOM   2738  O  OD2 . ASP A 1 349 ? 14.381  -18.792 11.270  1.00 47.54  ? 349 ASP A OD2 1 
ATOM   2739  N  N   . GLY A 1 350 ? 9.553   -19.196 8.680   1.00 34.65  ? 350 GLY A N   1 
ATOM   2740  C  CA  . GLY A 1 350 ? 8.525   -19.600 7.742   1.00 38.61  ? 350 GLY A CA  1 
ATOM   2741  C  C   . GLY A 1 350 ? 7.862   -20.871 8.238   1.00 39.56  ? 350 GLY A C   1 
ATOM   2742  O  O   . GLY A 1 350 ? 8.523   -21.776 8.760   1.00 44.09  ? 350 GLY A O   1 
ATOM   2743  N  N   . ILE A 1 351 ? 6.539   -20.943 8.096   1.00 36.25  ? 351 ILE A N   1 
ATOM   2744  C  CA  . ILE A 1 351 ? 5.851   -22.196 8.379   1.00 36.37  ? 351 ILE A CA  1 
ATOM   2745  C  C   . ILE A 1 351 ? 5.487   -22.955 7.110   1.00 41.45  ? 351 ILE A C   1 
ATOM   2746  O  O   . ILE A 1 351 ? 4.836   -24.008 7.199   1.00 40.46  ? 351 ILE A O   1 
ATOM   2747  C  CB  . ILE A 1 351 ? 4.616   -21.964 9.269   1.00 27.96  ? 351 ILE A CB  1 
ATOM   2748  C  CG1 . ILE A 1 351 ? 3.567   -21.116 8.568   1.00 29.76  ? 351 ILE A CG1 1 
ATOM   2749  C  CG2 . ILE A 1 351 ? 5.045   -21.305 10.568  1.00 37.67  ? 351 ILE A CG2 1 
ATOM   2750  C  CD1 . ILE A 1 351 ? 2.311   -20.954 9.382   1.00 30.89  ? 351 ILE A CD1 1 
ATOM   2751  N  N   . HIS A 1 352 ? 5.899   -22.454 5.939   1.00 36.11  ? 352 HIS A N   1 
ATOM   2752  C  CA  . HIS A 1 352 ? 5.829   -23.145 4.648   1.00 33.96  ? 352 HIS A CA  1 
ATOM   2753  C  C   . HIS A 1 352 ? 4.491   -23.849 4.435   1.00 37.48  ? 352 HIS A C   1 
ATOM   2754  O  O   . HIS A 1 352 ? 4.439   -25.034 4.100   1.00 32.46  ? 352 HIS A O   1 
ATOM   2755  C  CB  . HIS A 1 352 ? 6.967   -24.158 4.485   1.00 39.26  ? 352 HIS A CB  1 
ATOM   2756  C  CG  . HIS A 1 352 ? 8.275   -23.731 5.074   1.00 43.68  ? 352 HIS A CG  1 
ATOM   2757  N  ND1 . HIS A 1 352 ? 8.597   -23.930 6.400   1.00 48.30  ? 352 HIS A ND1 1 
ATOM   2758  C  CD2 . HIS A 1 352 ? 9.380   -23.197 4.499   1.00 47.12  ? 352 HIS A CD2 1 
ATOM   2759  C  CE1 . HIS A 1 352 ? 9.824   -23.489 6.626   1.00 50.39  ? 352 HIS A CE1 1 
ATOM   2760  N  NE2 . HIS A 1 352 ? 10.319  -23.031 5.489   1.00 49.75  ? 352 HIS A NE2 1 
ATOM   2761  N  N   . VAL A 1 353 ? 3.389   -23.116 4.618   1.00 32.66  ? 353 VAL A N   1 
ATOM   2762  C  CA  . VAL A 1 353 ? 2.095   -23.715 4.309   1.00 33.98  ? 353 VAL A CA  1 
ATOM   2763  C  C   . VAL A 1 353 ? 2.036   -24.000 2.811   1.00 38.90  ? 353 VAL A C   1 
ATOM   2764  O  O   . VAL A 1 353 ? 2.458   -23.182 1.981   1.00 33.51  ? 353 VAL A O   1 
ATOM   2765  C  CB  . VAL A 1 353 ? 0.924   -22.828 4.766   1.00 28.20  ? 353 VAL A CB  1 
ATOM   2766  C  CG1 . VAL A 1 353 ? -0.407  -23.334 4.184   1.00 32.85  ? 353 VAL A CG1 1 
ATOM   2767  C  CG2 . VAL A 1 353 ? 0.833   -22.792 6.292   1.00 25.19  ? 353 VAL A CG2 1 
ATOM   2768  N  N   . ASP A 1 354 ? 1.568   -25.198 2.470   1.00 37.23  ? 354 ASP A N   1 
ATOM   2769  C  CA  . ASP A 1 354 ? 1.351   -25.601 1.078   1.00 38.31  ? 354 ASP A CA  1 
ATOM   2770  C  C   . ASP A 1 354 ? 0.258   -24.746 0.453   1.00 33.66  ? 354 ASP A C   1 
ATOM   2771  O  O   . ASP A 1 354 ? -0.899  -24.832 0.887   1.00 36.44  ? 354 ASP A O   1 
ATOM   2772  C  CB  . ASP A 1 354 ? 0.955   -27.085 1.033   1.00 44.82  ? 354 ASP A CB  1 
ATOM   2773  C  CG  . ASP A 1 354 ? 1.079   -27.704 -0.365  1.00 48.75  ? 354 ASP A CG  1 
ATOM   2774  O  OD1 . ASP A 1 354 ? 1.438   -26.998 -1.339  1.00 46.43  ? 354 ASP A OD1 1 
ATOM   2775  O  OD2 . ASP A 1 354 ? 0.788   -28.914 -0.485  1.00 51.66  ? 354 ASP A OD2 1 
ATOM   2776  N  N   . PRO A 1 355 ? 0.561   -23.929 -0.560  1.00 35.43  ? 355 PRO A N   1 
ATOM   2777  C  CA  . PRO A 1 355 ? -0.484  -23.087 -1.164  1.00 35.61  ? 355 PRO A CA  1 
ATOM   2778  C  C   . PRO A 1 355 ? -1.735  -23.848 -1.556  1.00 38.25  ? 355 PRO A C   1 
ATOM   2779  O  O   . PRO A 1 355 ? -2.828  -23.275 -1.552  1.00 37.63  ? 355 PRO A O   1 
ATOM   2780  C  CB  . PRO A 1 355 ? 0.217   -22.506 -2.394  1.00 32.24  ? 355 PRO A CB  1 
ATOM   2781  C  CG  . PRO A 1 355 ? 1.659   -22.520 -2.037  1.00 31.89  ? 355 PRO A CG  1 
ATOM   2782  C  CD  . PRO A 1 355 ? 1.871   -23.731 -1.205  1.00 31.54  ? 355 PRO A CD  1 
ATOM   2783  N  N   . ASN A 1 356 ? -1.615  -25.131 -1.898  1.00 38.75  ? 356 ASN A N   1 
ATOM   2784  C  CA  . ASN A 1 356 ? -2.796  -25.875 -2.295  1.00 40.14  ? 356 ASN A CA  1 
ATOM   2785  C  C   . ASN A 1 356 ? -3.785  -26.026 -1.158  1.00 40.10  ? 356 ASN A C   1 
ATOM   2786  O  O   . ASN A 1 356 ? -4.973  -26.230 -1.427  1.00 41.33  ? 356 ASN A O   1 
ATOM   2787  C  CB  . ASN A 1 356 ? -2.395  -27.241 -2.839  1.00 44.91  ? 356 ASN A CB  1 
ATOM   2788  C  CG  . ASN A 1 356 ? -1.399  -27.128 -3.966  1.00 50.15  ? 356 ASN A CG  1 
ATOM   2789  O  OD1 . ASN A 1 356 ? -1.775  -26.979 -5.128  1.00 48.54  ? 356 ASN A OD1 1 
ATOM   2790  N  ND2 . ASN A 1 356 ? -0.115  -27.187 -3.628  1.00 58.11  ? 356 ASN A ND2 1 
ATOM   2791  N  N   . ASP A 1 357 ? -3.337  -25.886 0.100   1.00 40.84  ? 357 ASP A N   1 
ATOM   2792  C  CA  . ASP A 1 357 ? -4.255  -25.947 1.235   1.00 36.96  ? 357 ASP A CA  1 
ATOM   2793  C  C   . ASP A 1 357 ? -5.372  -24.925 1.137   1.00 36.22  ? 357 ASP A C   1 
ATOM   2794  O  O   . ASP A 1 357 ? -6.315  -24.992 1.933   1.00 40.19  ? 357 ASP A O   1 
ATOM   2795  C  CB  . ASP A 1 357 ? -3.520  -25.735 2.558   1.00 36.73  ? 357 ASP A CB  1 
ATOM   2796  C  CG  . ASP A 1 357 ? -2.561  -26.856 2.884   1.00 41.53  ? 357 ASP A CG  1 
ATOM   2797  O  OD1 . ASP A 1 357 ? -2.569  -27.875 2.163   1.00 42.08  ? 357 ASP A OD1 1 
ATOM   2798  O  OD2 . ASP A 1 357 ? -1.796  -26.718 3.866   1.00 41.17  ? 357 ASP A OD2 1 
ATOM   2799  N  N   . VAL A 1 358 ? -5.287  -23.979 0.198   1.00 32.16  ? 358 VAL A N   1 
ATOM   2800  C  CA  . VAL A 1 358 ? -6.376  -23.036 0.012   1.00 30.86  ? 358 VAL A CA  1 
ATOM   2801  C  C   . VAL A 1 358 ? -7.540  -23.643 -0.752  1.00 33.50  ? 358 VAL A C   1 
ATOM   2802  O  O   . VAL A 1 358 ? -8.648  -23.101 -0.685  1.00 38.10  ? 358 VAL A O   1 
ATOM   2803  C  CB  . VAL A 1 358 ? -5.889  -21.759 -0.707  1.00 32.67  ? 358 VAL A CB  1 
ATOM   2804  C  CG1 . VAL A 1 358 ? -4.624  -21.242 -0.052  1.00 31.20  ? 358 VAL A CG1 1 
ATOM   2805  C  CG2 . VAL A 1 358 ? -5.649  -22.024 -2.164  1.00 32.24  ? 358 VAL A CG2 1 
ATOM   2806  N  N   . PHE A 1 359 ? -7.333  -24.761 -1.464  1.00 36.44  ? 359 PHE A N   1 
ATOM   2807  C  CA  . PHE A 1 359 ? -8.408  -25.314 -2.288  1.00 37.71  ? 359 PHE A CA  1 
ATOM   2808  C  C   . PHE A 1 359 ? -9.611  -25.710 -1.439  1.00 39.25  ? 359 PHE A C   1 
ATOM   2809  O  O   . PHE A 1 359 ? -10.757 -25.412 -1.796  1.00 40.95  ? 359 PHE A O   1 
ATOM   2810  C  CB  . PHE A 1 359 ? -7.893  -26.509 -3.104  1.00 37.64  ? 359 PHE A CB  1 
ATOM   2811  C  CG  . PHE A 1 359 ? -7.135  -26.114 -4.358  1.00 37.04  ? 359 PHE A CG  1 
ATOM   2812  C  CD1 . PHE A 1 359 ? -5.757  -25.923 -4.333  1.00 37.37  ? 359 PHE A CD1 1 
ATOM   2813  C  CD2 . PHE A 1 359 ? -7.805  -25.916 -5.565  1.00 44.41  ? 359 PHE A CD2 1 
ATOM   2814  C  CE1 . PHE A 1 359 ? -5.064  -25.542 -5.473  1.00 35.62  ? 359 PHE A CE1 1 
ATOM   2815  C  CE2 . PHE A 1 359 ? -7.106  -25.535 -6.721  1.00 41.39  ? 359 PHE A CE2 1 
ATOM   2816  C  CZ  . PHE A 1 359 ? -5.741  -25.350 -6.669  1.00 37.76  ? 359 PHE A CZ  1 
ATOM   2817  N  N   . ASP A 1 360 ? -9.369  -26.356 -0.298  1.00 35.06  ? 360 ASP A N   1 
ATOM   2818  C  CA  . ASP A 1 360 ? -10.424 -26.840 0.583   1.00 37.49  ? 360 ASP A CA  1 
ATOM   2819  C  C   . ASP A 1 360 ? -11.090 -25.736 1.395   1.00 43.85  ? 360 ASP A C   1 
ATOM   2820  O  O   . ASP A 1 360 ? -12.140 -25.982 1.997   1.00 42.91  ? 360 ASP A O   1 
ATOM   2821  C  CB  . ASP A 1 360 ? -9.845  -27.885 1.537   1.00 44.95  ? 360 ASP A CB  1 
ATOM   2822  C  CG  . ASP A 1 360 ? -8.778  -28.738 0.877   1.00 55.31  ? 360 ASP A CG  1 
ATOM   2823  O  OD1 . ASP A 1 360 ? -9.121  -29.506 -0.054  1.00 52.33  ? 360 ASP A OD1 1 
ATOM   2824  O  OD2 . ASP A 1 360 ? -7.590  -28.624 1.273   1.00 60.67  ? 360 ASP A OD2 1 
ATOM   2825  N  N   . VAL A 1 361 ? -10.508 -24.539 1.430   1.00 40.18  ? 361 VAL A N   1 
ATOM   2826  C  CA  . VAL A 1 361 ? -11.085 -23.419 2.158   1.00 39.90  ? 361 VAL A CA  1 
ATOM   2827  C  C   . VAL A 1 361 ? -11.513 -22.283 1.243   1.00 35.42  ? 361 VAL A C   1 
ATOM   2828  O  O   . VAL A 1 361 ? -12.293 -21.424 1.680   1.00 38.35  ? 361 VAL A O   1 
ATOM   2829  C  CB  . VAL A 1 361 ? -10.108 -22.885 3.224   1.00 35.49  ? 361 VAL A CB  1 
ATOM   2830  C  CG1 . VAL A 1 361 ? -9.913  -23.906 4.332   1.00 38.49  ? 361 VAL A CG1 1 
ATOM   2831  C  CG2 . VAL A 1 361 ? -8.783  -22.507 2.588   1.00 33.06  ? 361 VAL A CG2 1 
ATOM   2832  N  N   . ILE A 1 362 ? -11.050 -22.254 -0.004  1.00 36.16  ? 362 ILE A N   1 
ATOM   2833  C  CA  . ILE A 1 362 ? -11.169 -21.059 -0.835  1.00 37.51  ? 362 ILE A CA  1 
ATOM   2834  C  C   . ILE A 1 362 ? -12.571 -20.459 -0.823  1.00 36.11  ? 362 ILE A C   1 
ATOM   2835  O  O   . ILE A 1 362 ? -12.722 -19.239 -0.892  1.00 36.17  ? 362 ILE A O   1 
ATOM   2836  C  CB  . ILE A 1 362 ? -10.710 -21.375 -2.269  1.00 36.87  ? 362 ILE A CB  1 
ATOM   2837  C  CG1 . ILE A 1 362 ? -10.154 -20.109 -2.924  1.00 38.32  ? 362 ILE A CG1 1 
ATOM   2838  C  CG2 . ILE A 1 362 ? -11.853 -21.918 -3.078  1.00 33.91  ? 362 ILE A CG2 1 
ATOM   2839  C  CD1 . ILE A 1 362 ? -8.807  -19.674 -2.368  1.00 36.41  ? 362 ILE A CD1 1 
ATOM   2840  N  N   . GLU A 1 363 ? -13.613 -21.286 -0.715  1.00 35.12  ? 363 GLU A N   1 
ATOM   2841  C  CA  . GLU A 1 363 ? -14.985 -20.798 -0.819  1.00 35.43  ? 363 GLU A CA  1 
ATOM   2842  C  C   . GLU A 1 363 ? -15.289 -19.753 0.240   1.00 41.40  ? 363 GLU A C   1 
ATOM   2843  O  O   . GLU A 1 363 ? -16.208 -18.944 0.057   1.00 40.06  ? 363 GLU A O   1 
ATOM   2844  C  CB  . GLU A 1 363 ? -15.985 -21.958 -0.672  1.00 42.78  ? 363 GLU A CB  1 
ATOM   2845  C  CG  . GLU A 1 363 ? -15.677 -23.194 -1.523  1.00 48.81  ? 363 GLU A CG  1 
ATOM   2846  C  CD  . GLU A 1 363 ? -14.475 -23.983 -1.004  1.00 48.51  ? 363 GLU A CD  1 
ATOM   2847  O  OE1 . GLU A 1 363 ? -14.413 -24.262 0.218   1.00 46.82  ? 363 GLU A OE1 1 
ATOM   2848  O  OE2 . GLU A 1 363 ? -13.576 -24.288 -1.820  1.00 48.35  ? 363 GLU A OE2 1 
ATOM   2849  N  N   . ASN A 1 364 ? -14.537 -19.776 1.343   1.00 40.53  ? 364 ASN A N   1 
ATOM   2850  C  CA  . ASN A 1 364 ? -14.691 -18.884 2.483   1.00 40.21  ? 364 ASN A CA  1 
ATOM   2851  C  C   . ASN A 1 364 ? -13.568 -17.852 2.593   1.00 35.39  ? 364 ASN A C   1 
ATOM   2852  O  O   . ASN A 1 364 ? -13.556 -17.067 3.559   1.00 35.79  ? 364 ASN A O   1 
ATOM   2853  C  CB  . ASN A 1 364 ? -14.743 -19.714 3.768   1.00 36.28  ? 364 ASN A CB  1 
ATOM   2854  C  CG  . ASN A 1 364 ? -16.001 -20.565 3.871   1.00 44.12  ? 364 ASN A CG  1 
ATOM   2855  O  OD1 . ASN A 1 364 ? -17.118 -20.074 3.712   1.00 40.89  ? 364 ASN A OD1 1 
ATOM   2856  N  ND2 . ASN A 1 364 ? -15.816 -21.863 4.114   1.00 47.38  ? 364 ASN A ND2 1 
ATOM   2857  N  N   . VAL A 1 365 ? -12.624 -17.832 1.651   1.00 34.70  ? 365 VAL A N   1 
ATOM   2858  C  CA  . VAL A 1 365 ? -11.538 -16.849 1.650   1.00 32.54  ? 365 VAL A CA  1 
ATOM   2859  C  C   . VAL A 1 365 ? -12.035 -15.619 0.890   1.00 37.16  ? 365 VAL A C   1 
ATOM   2860  O  O   . VAL A 1 365 ? -12.101 -15.602 -0.346  1.00 32.77  ? 365 VAL A O   1 
ATOM   2861  C  CB  . VAL A 1 365 ? -10.245 -17.418 1.058   1.00 32.99  ? 365 VAL A CB  1 
ATOM   2862  C  CG1 . VAL A 1 365 ? -9.248  -16.313 0.780   1.00 31.06  ? 365 VAL A CG1 1 
ATOM   2863  C  CG2 . VAL A 1 365 ? -9.623  -18.388 2.031   1.00 35.97  ? 365 VAL A CG2 1 
ATOM   2864  N  N   . VAL A 1 366 ? -12.385 -14.572 1.643   1.00 30.93  ? 366 VAL A N   1 
ATOM   2865  C  CA  . VAL A 1 366 ? -12.997 -13.378 1.068   1.00 30.81  ? 366 VAL A CA  1 
ATOM   2866  C  C   . VAL A 1 366 ? -12.009 -12.236 0.822   1.00 32.15  ? 366 VAL A C   1 
ATOM   2867  O  O   . VAL A 1 366 ? -12.342 -11.294 0.081   1.00 29.72  ? 366 VAL A O   1 
ATOM   2868  C  CB  . VAL A 1 366 ? -14.143 -12.896 1.972   1.00 30.38  ? 366 VAL A CB  1 
ATOM   2869  C  CG1 . VAL A 1 366 ? -15.140 -14.028 2.170   1.00 32.90  ? 366 VAL A CG1 1 
ATOM   2870  C  CG2 . VAL A 1 366 ? -13.585 -12.454 3.322   1.00 35.51  ? 366 VAL A CG2 1 
ATOM   2871  N  N   . PHE A 1 367 ? -10.806 -12.301 1.389   1.00 27.89  ? 367 PHE A N   1 
ATOM   2872  C  CA  . PHE A 1 367 ? -9.856  -11.200 1.343   1.00 27.56  ? 367 PHE A CA  1 
ATOM   2873  C  C   . PHE A 1 367 ? -8.480  -11.760 1.633   1.00 27.99  ? 367 PHE A C   1 
ATOM   2874  O  O   . PHE A 1 367 ? -8.335  -12.674 2.451   1.00 24.50  ? 367 PHE A O   1 
ATOM   2875  C  CB  . PHE A 1 367 ? -10.202 -10.102 2.367   1.00 29.31  ? 367 PHE A CB  1 
ATOM   2876  C  CG  . PHE A 1 367 ? -9.434  -8.800  2.153   1.00 28.92  ? 367 PHE A CG  1 
ATOM   2877  C  CD1 . PHE A 1 367 ? -9.810  -7.919  1.162   1.00 29.43  ? 367 PHE A CD1 1 
ATOM   2878  C  CD2 . PHE A 1 367 ? -8.342  -8.475  2.948   1.00 29.81  ? 367 PHE A CD2 1 
ATOM   2879  C  CE1 . PHE A 1 367 ? -9.120  -6.737  0.958   1.00 25.90  ? 367 PHE A CE1 1 
ATOM   2880  C  CE2 . PHE A 1 367 ? -7.655  -7.285  2.765   1.00 26.94  ? 367 PHE A CE2 1 
ATOM   2881  C  CZ  . PHE A 1 367 ? -8.048  -6.416  1.766   1.00 26.87  ? 367 PHE A CZ  1 
ATOM   2882  N  N   . ILE A 1 368 ? -7.466  -11.203 0.977   1.00 25.18  ? 368 ILE A N   1 
ATOM   2883  C  CA  . ILE A 1 368 ? -6.111  -11.685 1.185   1.00 24.21  ? 368 ILE A CA  1 
ATOM   2884  C  C   . ILE A 1 368 ? -5.161  -10.518 1.409   1.00 28.36  ? 368 ILE A C   1 
ATOM   2885  O  O   . ILE A 1 368 ? -5.079  -9.594  0.584   1.00 29.23  ? 368 ILE A O   1 
ATOM   2886  C  CB  . ILE A 1 368 ? -5.630  -12.566 0.027   1.00 24.91  ? 368 ILE A CB  1 
ATOM   2887  C  CG1 . ILE A 1 368 ? -6.503  -13.817 -0.056  1.00 30.75  ? 368 ILE A CG1 1 
ATOM   2888  C  CG2 . ILE A 1 368 ? -4.183  -12.966 0.260   1.00 26.29  ? 368 ILE A CG2 1 
ATOM   2889  C  CD1 . ILE A 1 368 ? -6.055  -14.783 -1.126  1.00 30.97  ? 368 ILE A CD1 1 
ATOM   2890  N  N   . GLN A 1 369 ? -4.435  -10.576 2.523   1.00 24.92  ? 369 GLN A N   1 
ATOM   2891  C  CA  . GLN A 1 369 ? -3.382  -9.624  2.829   1.00 24.34  ? 369 GLN A CA  1 
ATOM   2892  C  C   . GLN A 1 369 ? -2.081  -10.147 2.234   1.00 29.98  ? 369 GLN A C   1 
ATOM   2893  O  O   . GLN A 1 369 ? -1.601  -11.218 2.625   1.00 28.14  ? 369 GLN A O   1 
ATOM   2894  C  CB  . GLN A 1 369 ? -3.268  -9.427  4.345   1.00 29.05  ? 369 GLN A CB  1 
ATOM   2895  C  CG  . GLN A 1 369 ? -4.404  -8.582  4.939   1.00 24.82  ? 369 GLN A CG  1 
ATOM   2896  C  CD  . GLN A 1 369 ? -4.378  -8.530  6.457   1.00 28.72  ? 369 GLN A CD  1 
ATOM   2897  O  OE1 . GLN A 1 369 ? -3.641  -9.273  7.098   1.00 32.23  ? 369 GLN A OE1 1 
ATOM   2898  N  NE2 . GLN A 1 369 ? -5.180  -7.643  7.041   1.00 27.92  ? 369 GLN A NE2 1 
ATOM   2899  N  N   . ALA A 1 370 ? -1.523  -9.405  1.274   1.00 23.17  ? 370 ALA A N   1 
ATOM   2900  C  CA  . ALA A 1 370 ? -0.295  -9.816  0.597   1.00 27.97  ? 370 ALA A CA  1 
ATOM   2901  C  C   . ALA A 1 370 ? 0.899   -9.362  1.436   1.00 24.77  ? 370 ALA A C   1 
ATOM   2902  O  O   . ALA A 1 370 ? 1.636   -8.426  1.101   1.00 26.77  ? 370 ALA A O   1 
ATOM   2903  C  CB  . ALA A 1 370 ? -0.239  -9.268  -0.836  1.00 20.24  ? 370 ALA A CB  1 
ATOM   2904  N  N   . LYS A 1 371 ? 1.095   -10.075 2.547   1.00 25.62  ? 371 LYS A N   1 
ATOM   2905  C  CA  . LYS A 1 371 ? 2.253   -9.856  3.408   1.00 22.75  ? 371 LYS A CA  1 
ATOM   2906  C  C   . LYS A 1 371 ? 3.549   -10.234 2.694   1.00 27.36  ? 371 LYS A C   1 
ATOM   2907  O  O   . LYS A 1 371 ? 3.604   -11.210 1.934   1.00 27.81  ? 371 LYS A O   1 
ATOM   2908  C  CB  . LYS A 1 371 ? 2.085   -10.667 4.708   1.00 31.27  ? 371 LYS A CB  1 
ATOM   2909  C  CG  . LYS A 1 371 ? 3.357   -10.860 5.543   1.00 29.34  ? 371 LYS A CG  1 
ATOM   2910  C  CD  . LYS A 1 371 ? 3.723   -9.613  6.365   1.00 28.81  ? 371 LYS A CD  1 
ATOM   2911  C  CE  . LYS A 1 371 ? 2.566   -9.100  7.236   1.00 26.54  ? 371 LYS A CE  1 
ATOM   2912  N  NZ  . LYS A 1 371 ? 1.952   -10.145 8.114   1.00 33.59  ? 371 LYS A NZ  1 
ATOM   2913  N  N   . PHE A 1 372 ? 4.584   -9.417  2.903   1.00 22.81  ? 372 PHE A N   1 
ATOM   2914  C  CA  . PHE A 1 372 ? 5.911   -9.628  2.339   1.00 27.06  ? 372 PHE A CA  1 
ATOM   2915  C  C   . PHE A 1 372 ? 6.882   -8.775  3.145   1.00 23.02  ? 372 PHE A C   1 
ATOM   2916  O  O   . PHE A 1 372 ? 6.473   -7.904  3.907   1.00 25.55  ? 372 PHE A O   1 
ATOM   2917  C  CB  . PHE A 1 372 ? 5.973   -9.270  0.849   1.00 24.39  ? 372 PHE A CB  1 
ATOM   2918  C  CG  . PHE A 1 372 ? 6.020   -7.780  0.589   1.00 29.00  ? 372 PHE A CG  1 
ATOM   2919  C  CD1 . PHE A 1 372 ? 4.898   -6.999  0.785   1.00 27.49  ? 372 PHE A CD1 1 
ATOM   2920  C  CD2 . PHE A 1 372 ? 7.191   -7.167  0.171   1.00 28.68  ? 372 PHE A CD2 1 
ATOM   2921  C  CE1 . PHE A 1 372 ? 4.933   -5.630  0.558   1.00 28.48  ? 372 PHE A CE1 1 
ATOM   2922  C  CE2 . PHE A 1 372 ? 7.238   -5.806  -0.058  1.00 26.77  ? 372 PHE A CE2 1 
ATOM   2923  C  CZ  . PHE A 1 372 ? 6.104   -5.034  0.149   1.00 23.63  ? 372 PHE A CZ  1 
ATOM   2924  N  N   . HIS A 1 373 ? 8.167   -9.019  2.955   1.00 27.44  ? 373 HIS A N   1 
ATOM   2925  C  CA  . HIS A 1 373 ? 9.214   -8.445  3.799   1.00 25.82  ? 373 HIS A CA  1 
ATOM   2926  C  C   . HIS A 1 373 ? 10.301  -7.751  3.003   1.00 31.20  ? 373 HIS A C   1 
ATOM   2927  O  O   . HIS A 1 373 ? 10.801  -6.700  3.420   1.00 29.88  ? 373 HIS A O   1 
ATOM   2928  C  CB  . HIS A 1 373 ? 9.836   -9.551  4.681   1.00 23.42  ? 373 HIS A CB  1 
ATOM   2929  C  CG  . HIS A 1 373 ? 8.829   -10.251 5.544   1.00 30.00  ? 373 HIS A CG  1 
ATOM   2930  N  ND1 . HIS A 1 373 ? 8.416   -9.750  6.763   1.00 26.48  ? 373 HIS A ND1 1 
ATOM   2931  C  CD2 . HIS A 1 373 ? 8.119   -11.387 5.346   1.00 27.67  ? 373 HIS A CD2 1 
ATOM   2932  C  CE1 . HIS A 1 373 ? 7.496   -10.547 7.277   1.00 23.99  ? 373 HIS A CE1 1 
ATOM   2933  N  NE2 . HIS A 1 373 ? 7.303   -11.554 6.442   1.00 26.60  ? 373 HIS A NE2 1 
ATOM   2934  N  N   . ASP A 1 374 ? 10.677  -8.296  1.857   1.00 29.91  ? 374 ASP A N   1 
ATOM   2935  C  CA  . ASP A 1 374 ? 11.840  -7.765  1.177   1.00 28.41  ? 374 ASP A CA  1 
ATOM   2936  C  C   . ASP A 1 374 ? 11.787  -8.217  -0.268  1.00 33.25  ? 374 ASP A C   1 
ATOM   2937  O  O   . ASP A 1 374 ? 11.613  -9.407  -0.540  1.00 32.42  ? 374 ASP A O   1 
ATOM   2938  C  CB  . ASP A 1 374 ? 13.122  -8.238  1.855   1.00 26.30  ? 374 ASP A CB  1 
ATOM   2939  C  CG  . ASP A 1 374 ? 14.340  -7.529  1.336   1.00 34.63  ? 374 ASP A CG  1 
ATOM   2940  O  OD1 . ASP A 1 374 ? 14.184  -6.577  0.544   1.00 33.65  ? 374 ASP A OD1 1 
ATOM   2941  O  OD2 . ASP A 1 374 ? 15.457  -7.919  1.719   1.00 43.09  ? 374 ASP A OD2 1 
ATOM   2942  N  N   . ILE A 1 375 ? 11.897  -7.258  -1.182  1.00 30.69  ? 375 ILE A N   1 
ATOM   2943  C  CA  . ILE A 1 375 ? 11.958  -7.512  -2.613  1.00 31.10  ? 375 ILE A CA  1 
ATOM   2944  C  C   . ILE A 1 375 ? 13.051  -6.611  -3.154  1.00 29.46  ? 375 ILE A C   1 
ATOM   2945  O  O   . ILE A 1 375 ? 13.056  -5.412  -2.863  1.00 28.95  ? 375 ILE A O   1 
ATOM   2946  C  CB  . ILE A 1 375 ? 10.616  -7.228  -3.310  1.00 30.02  ? 375 ILE A CB  1 
ATOM   2947  C  CG1 . ILE A 1 375 ? 9.498   -8.068  -2.669  1.00 26.67  ? 375 ILE A CG1 1 
ATOM   2948  C  CG2 . ILE A 1 375 ? 10.736  -7.498  -4.805  1.00 28.18  ? 375 ILE A CG2 1 
ATOM   2949  C  CD1 . ILE A 1 375 ? 8.159   -7.941  -3.338  1.00 26.19  ? 375 ILE A CD1 1 
ATOM   2950  N  N   . ASP A 1 376 ? 13.991  -7.184  -3.895  1.00 28.99  ? 376 ASP A N   1 
ATOM   2951  C  CA  . ASP A 1 376 ? 15.198  -6.473  -4.279  1.00 35.24  ? 376 ASP A CA  1 
ATOM   2952  C  C   . ASP A 1 376 ? 15.025  -5.822  -5.660  1.00 35.01  ? 376 ASP A C   1 
ATOM   2953  O  O   . ASP A 1 376 ? 13.942  -5.850  -6.250  1.00 34.25  ? 376 ASP A O   1 
ATOM   2954  C  CB  . ASP A 1 376 ? 16.397  -7.422  -4.174  1.00 32.97  ? 376 ASP A CB  1 
ATOM   2955  C  CG  . ASP A 1 376 ? 16.402  -8.520  -5.238  1.00 36.22  ? 376 ASP A CG  1 
ATOM   2956  O  OD1 . ASP A 1 376 ? 15.576  -8.485  -6.176  1.00 39.79  ? 376 ASP A OD1 1 
ATOM   2957  O  OD2 . ASP A 1 376 ? 17.261  -9.422  -5.144  1.00 34.47  ? 376 ASP A OD2 1 
ATOM   2958  N  N   . GLU A 1 377 ? 16.107  -5.223  -6.180  1.00 35.71  ? 377 GLU A N   1 
ATOM   2959  C  CA  . GLU A 1 377 ? 16.132  -4.510  -7.458  1.00 32.94  ? 377 GLU A CA  1 
ATOM   2960  C  C   . GLU A 1 377 ? 15.754  -5.384  -8.637  1.00 37.82  ? 377 GLU A C   1 
ATOM   2961  O  O   . GLU A 1 377 ? 15.499  -4.842  -9.725  1.00 31.12  ? 377 GLU A O   1 
ATOM   2962  C  CB  . GLU A 1 377 ? 17.528  -3.937  -7.781  1.00 39.97  ? 377 GLU A CB  1 
ATOM   2963  C  CG  . GLU A 1 377 ? 18.200  -3.001  -6.761  1.00 44.16  ? 377 GLU A CG  1 
ATOM   2964  C  CD  . GLU A 1 377 ? 18.154  -3.524  -5.337  1.00 56.02  ? 377 GLU A CD  1 
ATOM   2965  O  OE1 . GLU A 1 377 ? 18.861  -4.526  -5.043  1.00 53.81  ? 377 GLU A OE1 1 
ATOM   2966  O  OE2 . GLU A 1 377 ? 17.390  -2.946  -4.521  1.00 57.33  ? 377 GLU A OE2 1 
ATOM   2967  N  N   . GLU A 1 378 ? 15.771  -6.709  -8.469  1.00 33.14  ? 378 GLU A N   1 
ATOM   2968  C  CA  . GLU A 1 378 ? 15.427  -7.648  -9.525  1.00 34.51  ? 378 GLU A CA  1 
ATOM   2969  C  C   . GLU A 1 378 ? 14.043  -8.225  -9.334  1.00 33.19  ? 378 GLU A C   1 
ATOM   2970  O  O   . GLU A 1 378 ? 13.675  -9.181  -10.024 1.00 36.58  ? 378 GLU A O   1 
ATOM   2971  C  CB  . GLU A 1 378 ? 16.460  -8.770  -9.592  1.00 32.86  ? 378 GLU A CB  1 
ATOM   2972  C  CG  . GLU A 1 378 ? 17.811  -8.289  -10.021 1.00 33.38  ? 378 GLU A CG  1 
ATOM   2973  C  CD  . GLU A 1 378 ? 17.826  -7.937  -11.485 1.00 45.01  ? 378 GLU A CD  1 
ATOM   2974  O  OE1 . GLU A 1 378 ? 17.746  -8.865  -12.317 1.00 52.20  ? 378 GLU A OE1 1 
ATOM   2975  O  OE2 . GLU A 1 378 ? 17.908  -6.737  -11.808 1.00 45.12  ? 378 GLU A OE2 1 
ATOM   2976  N  N   . LEU A 1 379 ? 13.265  -7.651  -8.425  1.00 30.72  ? 379 LEU A N   1 
ATOM   2977  C  CA  . LEU A 1 379 ? 11.929  -8.135  -8.097  1.00 29.77  ? 379 LEU A CA  1 
ATOM   2978  C  C   . LEU A 1 379 ? 11.959  -9.550  -7.521  1.00 35.58  ? 379 LEU A C   1 
ATOM   2979  O  O   . LEU A 1 379 ? 11.000  -10.316 -7.688  1.00 33.69  ? 379 LEU A O   1 
ATOM   2980  C  CB  . LEU A 1 379 ? 10.994  -8.064  -9.304  1.00 27.97  ? 379 LEU A CB  1 
ATOM   2981  C  CG  . LEU A 1 379 ? 10.600  -6.643  -9.662  1.00 29.04  ? 379 LEU A CG  1 
ATOM   2982  C  CD1 . LEU A 1 379 ? 9.385   -6.675  -10.571 1.00 29.58  ? 379 LEU A CD1 1 
ATOM   2983  C  CD2 . LEU A 1 379 ? 10.318  -5.819  -8.393  1.00 25.62  ? 379 LEU A CD2 1 
ATOM   2984  N  N   . ASP A 1 380 ? 13.042  -9.897  -6.816  1.00 34.11  ? 380 ASP A N   1 
ATOM   2985  C  CA  . ASP A 1 380 ? 13.147  -11.176 -6.105  1.00 35.12  ? 380 ASP A CA  1 
ATOM   2986  C  C   . ASP A 1 380 ? 12.718  -10.991 -4.655  1.00 32.19  ? 380 ASP A C   1 
ATOM   2987  O  O   . ASP A 1 380 ? 13.413  -10.332 -3.874  1.00 32.31  ? 380 ASP A O   1 
ATOM   2988  C  CB  . ASP A 1 380 ? 14.570  -11.725 -6.156  1.00 34.71  ? 380 ASP A CB  1 
ATOM   2989  C  CG  . ASP A 1 380 ? 14.670  -13.116 -5.561  1.00 37.13  ? 380 ASP A CG  1 
ATOM   2990  O  OD1 . ASP A 1 380 ? 13.766  -13.942 -5.808  1.00 41.02  ? 380 ASP A OD1 1 
ATOM   2991  O  OD2 . ASP A 1 380 ? 15.650  -13.381 -4.841  1.00 39.54  ? 380 ASP A OD2 1 
ATOM   2992  N  N   . ASP A 1 381 ? 11.577  -11.573 -4.301  1.00 30.13  ? 381 ASP A N   1 
ATOM   2993  C  CA  . ASP A 1 381 ? 11.127  -11.606 -2.917  1.00 30.75  ? 381 ASP A CA  1 
ATOM   2994  C  C   . ASP A 1 381 ? 11.945  -12.616 -2.125  1.00 31.75  ? 381 ASP A C   1 
ATOM   2995  O  O   . ASP A 1 381 ? 12.154  -13.749 -2.568  1.00 33.18  ? 381 ASP A O   1 
ATOM   2996  C  CB  . ASP A 1 381 ? 9.640   -11.974 -2.853  1.00 29.26  ? 381 ASP A CB  1 
ATOM   2997  C  CG  . ASP A 1 381 ? 9.032   -11.749 -1.471  1.00 32.88  ? 381 ASP A CG  1 
ATOM   2998  O  OD1 . ASP A 1 381 ? 9.474   -12.420 -0.509  1.00 31.16  ? 381 ASP A OD1 1 
ATOM   2999  O  OD2 . ASP A 1 381 ? 8.108   -10.907 -1.351  1.00 29.89  ? 381 ASP A OD2 1 
ATOM   3000  N  N   . LYS A 1 382 ? 12.370  -12.216 -0.928  1.00 29.39  ? 382 LYS A N   1 
ATOM   3001  C  CA  . LYS A 1 382 ? 13.319  -12.990 -0.139  1.00 28.91  ? 382 LYS A CA  1 
ATOM   3002  C  C   . LYS A 1 382 ? 12.664  -13.938 0.862   1.00 31.42  ? 382 LYS A C   1 
ATOM   3003  O  O   . LYS A 1 382 ? 13.387  -14.637 1.579   1.00 32.14  ? 382 LYS A O   1 
ATOM   3004  C  CB  . LYS A 1 382 ? 14.276  -12.052 0.599   1.00 30.39  ? 382 LYS A CB  1 
ATOM   3005  C  CG  . LYS A 1 382 ? 15.096  -11.131 -0.312  1.00 26.54  ? 382 LYS A CG  1 
ATOM   3006  C  CD  . LYS A 1 382 ? 15.802  -11.886 -1.432  1.00 30.59  ? 382 LYS A CD  1 
ATOM   3007  C  CE  . LYS A 1 382 ? 16.579  -10.926 -2.342  1.00 30.57  ? 382 LYS A CE  1 
ATOM   3008  N  NZ  . LYS A 1 382 ? 17.193  -11.591 -3.523  1.00 34.14  ? 382 LYS A NZ  1 
ATOM   3009  N  N   . GLN A 1 383 ? 11.330  -13.999 0.934   1.00 30.07  ? 383 GLN A N   1 
ATOM   3010  C  CA  . GLN A 1 383 ? 10.684  -14.895 1.890   1.00 28.92  ? 383 GLN A CA  1 
ATOM   3011  C  C   . GLN A 1 383 ? 9.434   -15.578 1.336   1.00 34.23  ? 383 GLN A C   1 
ATOM   3012  O  O   . GLN A 1 383 ? 9.172   -16.742 1.658   1.00 32.12  ? 383 GLN A O   1 
ATOM   3013  C  CB  . GLN A 1 383 ? 10.301  -14.148 3.176   1.00 25.90  ? 383 GLN A CB  1 
ATOM   3014  C  CG  . GLN A 1 383 ? 11.455  -13.813 4.139   1.00 30.71  ? 383 GLN A CG  1 
ATOM   3015  C  CD  . GLN A 1 383 ? 12.266  -12.613 3.689   1.00 26.91  ? 383 GLN A CD  1 
ATOM   3016  O  OE1 . GLN A 1 383 ? 11.725  -11.658 3.131   1.00 32.67  ? 383 GLN A OE1 1 
ATOM   3017  N  NE2 . GLN A 1 383 ? 13.573  -12.658 3.918   1.00 31.48  ? 383 GLN A NE2 1 
ATOM   3018  N  N   . ILE A 1 384 ? 8.629   -14.875 0.547   1.00 30.19  ? 384 ILE A N   1 
ATOM   3019  C  CA  . ILE A 1 384 ? 7.320   -15.370 0.132   1.00 29.31  ? 384 ILE A CA  1 
ATOM   3020  C  C   . ILE A 1 384 ? 7.433   -15.943 -1.277  1.00 32.02  ? 384 ILE A C   1 
ATOM   3021  O  O   . ILE A 1 384 ? 7.833   -15.215 -2.199  1.00 30.94  ? 384 ILE A O   1 
ATOM   3022  C  CB  . ILE A 1 384 ? 6.255   -14.276 0.201   1.00 26.39  ? 384 ILE A CB  1 
ATOM   3023  C  CG1 . ILE A 1 384 ? 6.371   -13.541 1.526   1.00 28.63  ? 384 ILE A CG1 1 
ATOM   3024  C  CG2 . ILE A 1 384 ? 4.880   -14.894 0.087   1.00 31.76  ? 384 ILE A CG2 1 
ATOM   3025  C  CD1 . ILE A 1 384 ? 6.040   -14.430 2.721   1.00 26.29  ? 384 ILE A CD1 1 
ATOM   3026  N  N   . PRO A 1 385 ? 7.100   -17.213 -1.488  1.00 34.35  ? 385 PRO A N   1 
ATOM   3027  C  CA  . PRO A 1 385 ? 7.175   -17.780 -2.840  1.00 31.19  ? 385 PRO A CA  1 
ATOM   3028  C  C   . PRO A 1 385 ? 5.958   -17.408 -3.671  1.00 32.94  ? 385 PRO A C   1 
ATOM   3029  O  O   . PRO A 1 385 ? 4.960   -18.124 -3.635  1.00 31.03  ? 385 PRO A O   1 
ATOM   3030  C  CB  . PRO A 1 385 ? 7.241   -19.288 -2.569  1.00 38.12  ? 385 PRO A CB  1 
ATOM   3031  C  CG  . PRO A 1 385 ? 6.471   -19.460 -1.287  1.00 35.49  ? 385 PRO A CG  1 
ATOM   3032  C  CD  . PRO A 1 385 ? 6.767   -18.229 -0.472  1.00 34.74  ? 385 PRO A CD  1 
ATOM   3033  N  N   . TRP A 1 386 ? 6.020   -16.321 -4.448  1.00 34.76  ? 386 TRP A N   1 
ATOM   3034  C  CA  . TRP A 1 386 ? 4.779   -15.730 -4.954  1.00 34.04  ? 386 TRP A CA  1 
ATOM   3035  C  C   . TRP A 1 386 ? 4.168   -16.529 -6.102  1.00 31.14  ? 386 TRP A C   1 
ATOM   3036  O  O   . TRP A 1 386 ? 2.939   -16.662 -6.176  1.00 32.75  ? 386 TRP A O   1 
ATOM   3037  C  CB  . TRP A 1 386 ? 5.024   -14.276 -5.359  1.00 32.02  ? 386 TRP A CB  1 
ATOM   3038  C  CG  . TRP A 1 386 ? 4.990   -13.360 -4.157  1.00 27.23  ? 386 TRP A CG  1 
ATOM   3039  C  CD1 . TRP A 1 386 ? 6.045   -12.722 -3.583  1.00 21.33  ? 386 TRP A CD1 1 
ATOM   3040  C  CD2 . TRP A 1 386 ? 3.844   -13.023 -3.369  1.00 24.60  ? 386 TRP A CD2 1 
ATOM   3041  N  NE1 . TRP A 1 386 ? 5.631   -11.993 -2.514  1.00 23.31  ? 386 TRP A NE1 1 
ATOM   3042  C  CE2 . TRP A 1 386 ? 4.284   -12.160 -2.348  1.00 26.20  ? 386 TRP A CE2 1 
ATOM   3043  C  CE3 . TRP A 1 386 ? 2.491   -13.358 -3.433  1.00 20.95  ? 386 TRP A CE3 1 
ATOM   3044  C  CZ2 . TRP A 1 386 ? 3.421   -11.632 -1.385  1.00 19.67  ? 386 TRP A CZ2 1 
ATOM   3045  C  CZ3 . TRP A 1 386 ? 1.637   -12.843 -2.481  1.00 23.16  ? 386 TRP A CZ3 1 
ATOM   3046  C  CH2 . TRP A 1 386 ? 2.111   -11.983 -1.464  1.00 24.56  ? 386 TRP A CH2 1 
ATOM   3047  N  N   . GLU A 1 387 ? 4.998   -17.093 -6.986  1.00 34.95  ? 387 GLU A N   1 
ATOM   3048  C  CA  . GLU A 1 387 ? 4.467   -17.868 -8.107  1.00 31.81  ? 387 GLU A CA  1 
ATOM   3049  C  C   . GLU A 1 387 ? 3.585   -19.024 -7.663  1.00 33.35  ? 387 GLU A C   1 
ATOM   3050  O  O   . GLU A 1 387 ? 2.444   -19.111 -8.151  1.00 36.87  ? 387 GLU A O   1 
ATOM   3051  C  CB  . GLU A 1 387 ? 5.613   -18.351 -9.008  1.00 31.77  ? 387 GLU A CB  1 
ATOM   3052  C  CG  . GLU A 1 387 ? 6.473   -17.214 -9.586  1.00 44.71  ? 387 GLU A CG  1 
ATOM   3053  C  CD  . GLU A 1 387 ? 7.677   -16.885 -8.725  1.00 41.99  ? 387 GLU A CD  1 
ATOM   3054  O  OE1 . GLU A 1 387 ? 7.580   -16.997 -7.479  1.00 42.25  ? 387 GLU A OE1 1 
ATOM   3055  O  OE2 . GLU A 1 387 ? 8.722   -16.503 -9.297  1.00 47.79  ? 387 GLU A OE2 1 
ATOM   3056  N  N   . PRO A 1 388 ? 4.016   -19.939 -6.773  1.00 32.13  ? 388 PRO A N   1 
ATOM   3057  C  CA  . PRO A 1 388 ? 3.085   -21.002 -6.357  1.00 29.51  ? 388 PRO A CA  1 
ATOM   3058  C  C   . PRO A 1 388 ? 1.868   -20.497 -5.619  1.00 29.12  ? 388 PRO A C   1 
ATOM   3059  O  O   . PRO A 1 388 ? 0.769   -21.007 -5.858  1.00 33.93  ? 388 PRO A O   1 
ATOM   3060  C  CB  . PRO A 1 388 ? 3.946   -21.923 -5.476  1.00 31.97  ? 388 PRO A CB  1 
ATOM   3061  C  CG  . PRO A 1 388 ? 5.220   -21.226 -5.250  1.00 25.75  ? 388 PRO A CG  1 
ATOM   3062  C  CD  . PRO A 1 388 ? 5.402   -20.266 -6.385  1.00 31.51  ? 388 PRO A CD  1 
ATOM   3063  N  N   . VAL A 1 389 ? 2.014   -19.513 -4.727  1.00 31.22  ? 389 VAL A N   1 
ATOM   3064  C  CA  . VAL A 1 389 ? 0.841   -18.982 -4.035  1.00 26.81  ? 389 VAL A CA  1 
ATOM   3065  C  C   . VAL A 1 389 ? -0.173  -18.487 -5.045  1.00 28.60  ? 389 VAL A C   1 
ATOM   3066  O  O   . VAL A 1 389 ? -1.357  -18.847 -4.998  1.00 30.16  ? 389 VAL A O   1 
ATOM   3067  C  CB  . VAL A 1 389 ? 1.243   -17.862 -3.062  1.00 26.73  ? 389 VAL A CB  1 
ATOM   3068  C  CG1 . VAL A 1 389 ? 0.025   -17.072 -2.665  1.00 29.04  ? 389 VAL A CG1 1 
ATOM   3069  C  CG2 . VAL A 1 389 ? 1.898   -18.440 -1.860  1.00 27.94  ? 389 VAL A CG2 1 
ATOM   3070  N  N   . LEU A 1 390 ? 0.294   -17.678 -5.997  1.00 26.82  ? 390 LEU A N   1 
ATOM   3071  C  CA  . LEU A 1 390 ? -0.591  -17.114 -7.005  1.00 30.96  ? 390 LEU A CA  1 
ATOM   3072  C  C   . LEU A 1 390 ? -1.182  -18.205 -7.887  1.00 29.77  ? 390 LEU A C   1 
ATOM   3073  O  O   . LEU A 1 390 ? -2.390  -18.216 -8.134  1.00 33.40  ? 390 LEU A O   1 
ATOM   3074  C  CB  . LEU A 1 390 ? 0.169   -16.077 -7.836  1.00 28.72  ? 390 LEU A CB  1 
ATOM   3075  C  CG  . LEU A 1 390 ? 0.559   -14.825 -7.033  1.00 31.14  ? 390 LEU A CG  1 
ATOM   3076  C  CD1 . LEU A 1 390 ? 1.261   -13.804 -7.906  1.00 28.15  ? 390 LEU A CD1 1 
ATOM   3077  C  CD2 . LEU A 1 390 ? -0.671  -14.217 -6.359  1.00 29.51  ? 390 LEU A CD2 1 
ATOM   3078  N  N   . LYS A 1 391 ? -0.345  -19.136 -8.368  1.00 33.80  ? 391 LYS A N   1 
ATOM   3079  C  CA  . LYS A 1 391 ? -0.844  -20.280 -9.142  1.00 30.95  ? 391 LYS A CA  1 
ATOM   3080  C  C   . LYS A 1 391 ? -1.997  -20.966 -8.427  1.00 31.99  ? 391 LYS A C   1 
ATOM   3081  O  O   . LYS A 1 391 ? -3.092  -21.120 -8.982  1.00 35.19  ? 391 LYS A O   1 
ATOM   3082  C  CB  . LYS A 1 391 ? 0.296   -21.272 -9.402  1.00 32.73  ? 391 LYS A CB  1 
ATOM   3083  C  CG  . LYS A 1 391 ? -0.106  -22.655 -9.964  1.00 38.34  ? 391 LYS A CG  1 
ATOM   3084  C  CD  . LYS A 1 391 ? -0.756  -22.567 -11.340 1.00 38.89  ? 391 LYS A CD  1 
ATOM   3085  C  CE  . LYS A 1 391 ? 0.166   -23.100 -12.435 1.00 47.92  ? 391 LYS A CE  1 
ATOM   3086  N  NZ  . LYS A 1 391 ? -0.587  -23.609 -13.631 1.00 46.97  ? 391 LYS A NZ  1 
ATOM   3087  N  N   . ALA A 1 392 ? -1.778  -21.341 -7.167  1.00 34.86  ? 392 ALA A N   1 
ATOM   3088  C  CA  . ALA A 1 392 ? -2.812  -22.019 -6.401  1.00 34.07  ? 392 ALA A CA  1 
ATOM   3089  C  C   . ALA A 1 392 ? -4.029  -21.132 -6.241  1.00 37.33  ? 392 ALA A C   1 
ATOM   3090  O  O   . ALA A 1 392 ? -5.168  -21.583 -6.420  1.00 36.10  ? 392 ALA A O   1 
ATOM   3091  C  CB  . ALA A 1 392 ? -2.273  -22.427 -5.032  1.00 33.90  ? 392 ALA A CB  1 
ATOM   3092  N  N   . LEU A 1 393 ? -3.808  -19.863 -5.885  1.00 31.22  ? 393 LEU A N   1 
ATOM   3093  C  CA  . LEU A 1 393 ? -4.929  -18.952 -5.680  1.00 32.86  ? 393 LEU A CA  1 
ATOM   3094  C  C   . LEU A 1 393 ? -5.747  -18.787 -6.960  1.00 34.07  ? 393 LEU A C   1 
ATOM   3095  O  O   . LEU A 1 393 ? -6.986  -18.742 -6.926  1.00 34.81  ? 393 LEU A O   1 
ATOM   3096  C  CB  . LEU A 1 393 ? -4.410  -17.598 -5.201  1.00 31.43  ? 393 LEU A CB  1 
ATOM   3097  C  CG  . LEU A 1 393 ? -4.033  -17.460 -3.728  1.00 28.06  ? 393 LEU A CG  1 
ATOM   3098  C  CD1 . LEU A 1 393 ? -3.696  -15.995 -3.509  1.00 34.65  ? 393 LEU A CD1 1 
ATOM   3099  C  CD2 . LEU A 1 393 ? -5.148  -17.934 -2.802  1.00 24.82  ? 393 LEU A CD2 1 
ATOM   3100  N  N   . LYS A 1 394 ? -5.069  -18.696 -8.099  1.00 34.41  ? 394 LYS A N   1 
ATOM   3101  C  CA  . LYS A 1 394 ? -5.768  -18.579 -9.373  1.00 36.69  ? 394 LYS A CA  1 
ATOM   3102  C  C   . LYS A 1 394 ? -6.564  -19.846 -9.674  1.00 36.77  ? 394 LYS A C   1 
ATOM   3103  O  O   . LYS A 1 394 ? -7.799  -19.818 -9.773  1.00 37.98  ? 394 LYS A O   1 
ATOM   3104  C  CB  . LYS A 1 394 ? -4.760  -18.283 -10.476 1.00 30.53  ? 394 LYS A CB  1 
ATOM   3105  C  CG  . LYS A 1 394 ? -5.414  -17.905 -11.790 1.00 37.00  ? 394 LYS A CG  1 
ATOM   3106  C  CD  . LYS A 1 394 ? -4.594  -18.411 -12.950 1.00 38.74  ? 394 LYS A CD  1 
ATOM   3107  C  CE  . LYS A 1 394 ? -4.943  -17.673 -14.240 1.00 43.78  ? 394 LYS A CE  1 
ATOM   3108  N  NZ  . LYS A 1 394 ? -5.267  -18.648 -15.323 1.00 48.51  ? 394 LYS A NZ  1 
ATOM   3109  N  N   . ASP A 1 395 ? -5.866  -20.980 -9.783  1.00 37.41  ? 395 ASP A N   1 
ATOM   3110  C  CA  . ASP A 1 395 ? -6.533  -22.239 -10.087 1.00 39.08  ? 395 ASP A CA  1 
ATOM   3111  C  C   . ASP A 1 395 ? -7.665  -22.518 -9.118  1.00 39.22  ? 395 ASP A C   1 
ATOM   3112  O  O   . ASP A 1 395 ? -8.679  -23.111 -9.498  1.00 39.83  ? 395 ASP A O   1 
ATOM   3113  C  CB  . ASP A 1 395 ? -5.527  -23.388 -10.066 1.00 35.82  ? 395 ASP A CB  1 
ATOM   3114  C  CG  . ASP A 1 395 ? -4.469  -23.239 -11.130 1.00 37.75  ? 395 ASP A CG  1 
ATOM   3115  O  OD1 . ASP A 1 395 ? -4.615  -22.331 -11.977 1.00 33.96  ? 395 ASP A OD1 1 
ATOM   3116  O  OD2 . ASP A 1 395 ? -3.498  -24.025 -11.122 1.00 44.32  ? 395 ASP A OD2 1 
ATOM   3117  N  N   . ALA A 1 396 ? -7.532  -22.075 -7.871  1.00 39.40  ? 396 ALA A N   1 
ATOM   3118  C  CA  . ALA A 1 396 ? -8.594  -22.339 -6.917  1.00 35.24  ? 396 ALA A CA  1 
ATOM   3119  C  C   . ALA A 1 396 ? -9.808  -21.456 -7.151  1.00 35.98  ? 396 ALA A C   1 
ATOM   3120  O  O   . ALA A 1 396 ? -10.850 -21.693 -6.533  1.00 30.62  ? 396 ALA A O   1 
ATOM   3121  C  CB  . ALA A 1 396 ? -8.073  -22.177 -5.488  1.00 37.40  ? 396 ALA A CB  1 
ATOM   3122  N  N   . GLY A 1 397 ? -9.706  -20.464 -8.038  1.00 39.94  ? 397 GLY A N   1 
ATOM   3123  C  CA  . GLY A 1 397 ? -10.836 -19.618 -8.372  1.00 36.30  ? 397 GLY A CA  1 
ATOM   3124  C  C   . GLY A 1 397 ? -10.964 -18.339 -7.575  1.00 34.38  ? 397 GLY A C   1 
ATOM   3125  O  O   . GLY A 1 397 ? -12.072 -17.792 -7.492  1.00 26.99  ? 397 GLY A O   1 
ATOM   3126  N  N   . TYR A 1 398 ? -9.877  -17.854 -6.970  1.00 34.57  ? 398 TYR A N   1 
ATOM   3127  C  CA  . TYR A 1 398 ? -9.929  -16.620 -6.193  1.00 38.05  ? 398 TYR A CA  1 
ATOM   3128  C  C   . TYR A 1 398 ? -9.842  -15.419 -7.121  1.00 32.68  ? 398 TYR A C   1 
ATOM   3129  O  O   . TYR A 1 398 ? -8.935  -15.326 -7.949  1.00 34.16  ? 398 TYR A O   1 
ATOM   3130  C  CB  . TYR A 1 398 ? -8.789  -16.551 -5.175  1.00 35.14  ? 398 TYR A CB  1 
ATOM   3131  C  CG  . TYR A 1 398 ? -8.823  -15.297 -4.312  1.00 31.71  ? 398 TYR A CG  1 
ATOM   3132  C  CD1 . TYR A 1 398 ? -9.717  -15.177 -3.265  1.00 31.74  ? 398 TYR A CD1 1 
ATOM   3133  C  CD2 . TYR A 1 398 ? -7.944  -14.239 -4.545  1.00 30.30  ? 398 TYR A CD2 1 
ATOM   3134  C  CE1 . TYR A 1 398 ? -9.735  -14.033 -2.457  1.00 32.70  ? 398 TYR A CE1 1 
ATOM   3135  C  CE2 . TYR A 1 398 ? -7.961  -13.105 -3.760  1.00 25.94  ? 398 TYR A CE2 1 
ATOM   3136  C  CZ  . TYR A 1 398 ? -8.849  -13.001 -2.719  1.00 32.31  ? 398 TYR A CZ  1 
ATOM   3137  O  OH  . TYR A 1 398 ? -8.860  -11.851 -1.935  1.00 27.41  ? 398 TYR A OH  1 
ATOM   3138  N  N   . THR A 1 399 ? -10.761 -14.481 -6.951  1.00 33.87  ? 399 THR A N   1 
ATOM   3139  C  CA  . THR A 1 399 ? -10.794 -13.292 -7.785  1.00 34.80  ? 399 THR A CA  1 
ATOM   3140  C  C   . THR A 1 399 ? -10.857 -12.012 -6.954  1.00 33.14  ? 399 THR A C   1 
ATOM   3141  O  O   . THR A 1 399 ? -11.098 -10.943 -7.515  1.00 39.10  ? 399 THR A O   1 
ATOM   3142  C  CB  . THR A 1 399 ? -11.991 -13.355 -8.741  1.00 34.26  ? 399 THR A CB  1 
ATOM   3143  O  OG1 . THR A 1 399 ? -13.200 -13.446 -7.973  1.00 38.38  ? 399 THR A OG1 1 
ATOM   3144  C  CG2 . THR A 1 399 ? -11.899 -14.596 -9.654  1.00 30.81  ? 399 THR A CG2 1 
ATOM   3145  N  N   . GLY A 1 400 ? -10.665 -12.088 -5.636  1.00 34.91  ? 400 GLY A N   1 
ATOM   3146  C  CA  . GLY A 1 400 ? -10.734 -10.922 -4.775  1.00 32.51  ? 400 GLY A CA  1 
ATOM   3147  C  C   . GLY A 1 400 ? -9.420  -10.159 -4.714  1.00 28.68  ? 400 GLY A C   1 
ATOM   3148  O  O   . GLY A 1 400 ? -8.521  -10.348 -5.536  1.00 23.50  ? 400 GLY A O   1 
ATOM   3149  N  N   . TYR A 1 401 ? -9.300  -9.316  -3.680  1.00 29.75  ? 401 TYR A N   1 
ATOM   3150  C  CA  . TYR A 1 401 ? -8.174  -8.394  -3.509  1.00 24.85  ? 401 TYR A CA  1 
ATOM   3151  C  C   . TYR A 1 401 ? -6.909  -9.086  -2.992  1.00 27.93  ? 401 TYR A C   1 
ATOM   3152  O  O   . TYR A 1 401 ? -6.972  -10.061 -2.235  1.00 26.89  ? 401 TYR A O   1 
ATOM   3153  C  CB  . TYR A 1 401 ? -8.567  -7.291  -2.526  1.00 26.47  ? 401 TYR A CB  1 
ATOM   3154  C  CG  . TYR A 1 401 ? -9.102  -6.052  -3.177  1.00 25.88  ? 401 TYR A CG  1 
ATOM   3155  C  CD1 . TYR A 1 401 ? -8.229  -5.101  -3.710  1.00 24.80  ? 401 TYR A CD1 1 
ATOM   3156  C  CD2 . TYR A 1 401 ? -10.479 -5.841  -3.298  1.00 26.88  ? 401 TYR A CD2 1 
ATOM   3157  C  CE1 . TYR A 1 401 ? -8.711  -3.960  -4.328  1.00 26.18  ? 401 TYR A CE1 1 
ATOM   3158  C  CE2 . TYR A 1 401 ? -10.975 -4.711  -3.909  1.00 28.82  ? 401 TYR A CE2 1 
ATOM   3159  C  CZ  . TYR A 1 401 ? -10.079 -3.772  -4.427  1.00 32.27  ? 401 TYR A CZ  1 
ATOM   3160  O  OH  . TYR A 1 401 ? -10.541 -2.639  -5.046  1.00 30.29  ? 401 TYR A OH  1 
ATOM   3161  N  N   . LEU A 1 402 ? -5.749  -8.530  -3.370  1.00 23.10  ? 402 LEU A N   1 
ATOM   3162  C  CA  . LEU A 1 402 ? -4.456  -8.802  -2.735  1.00 25.95  ? 402 LEU A CA  1 
ATOM   3163  C  C   . LEU A 1 402 ? -3.942  -7.490  -2.146  1.00 28.04  ? 402 LEU A C   1 
ATOM   3164  O  O   . LEU A 1 402 ? -3.484  -6.611  -2.884  1.00 28.54  ? 402 LEU A O   1 
ATOM   3165  C  CB  . LEU A 1 402 ? -3.436  -9.364  -3.728  1.00 26.68  ? 402 LEU A CB  1 
ATOM   3166  C  CG  . LEU A 1 402 ? -3.657  -10.733 -4.367  1.00 28.28  ? 402 LEU A CG  1 
ATOM   3167  C  CD1 . LEU A 1 402 ? -2.478  -11.002 -5.251  1.00 32.08  ? 402 LEU A CD1 1 
ATOM   3168  C  CD2 . LEU A 1 402 ? -3.851  -11.871 -3.322  1.00 25.01  ? 402 LEU A CD2 1 
ATOM   3169  N  N   . SER A 1 403 ? -3.983  -7.358  -0.824  1.00 28.11  ? 403 SER A N   1 
ATOM   3170  C  CA  . SER A 1 403 ? -3.771  -6.075  -0.155  1.00 24.56  ? 403 SER A CA  1 
ATOM   3171  C  C   . SER A 1 403 ? -2.394  -6.040  0.516   1.00 25.58  ? 403 SER A C   1 
ATOM   3172  O  O   . SER A 1 403 ? -2.193  -6.667  1.563   1.00 23.71  ? 403 SER A O   1 
ATOM   3173  C  CB  . SER A 1 403 ? -4.889  -5.848  0.852   1.00 27.71  ? 403 SER A CB  1 
ATOM   3174  O  OG  . SER A 1 403 ? -4.915  -4.527  1.344   1.00 31.55  ? 403 SER A OG  1 
ATOM   3175  N  N   . SER A 1 404 ? -1.476  -5.250  -0.056  1.00 22.18  ? 404 SER A N   1 
ATOM   3176  C  CA  . SER A 1 404 ? -0.086  -5.158  0.399   1.00 20.79  ? 404 SER A CA  1 
ATOM   3177  C  C   . SER A 1 404 ? 0.006   -4.912  1.894   1.00 23.19  ? 404 SER A C   1 
ATOM   3178  O  O   . SER A 1 404 ? -0.560  -3.948  2.412   1.00 24.95  ? 404 SER A O   1 
ATOM   3179  C  CB  . SER A 1 404 ? 0.647   -4.030  -0.332  1.00 22.37  ? 404 SER A CB  1 
ATOM   3180  O  OG  . SER A 1 404 ? 0.696   -4.241  -1.734  1.00 29.50  ? 404 SER A OG  1 
ATOM   3181  N  N   . GLU A 1 405 ? 0.754   -5.781  2.586   1.00 23.99  ? 405 GLU A N   1 
ATOM   3182  C  CA  . GLU A 1 405 ? 1.109   -5.596  3.993   1.00 24.09  ? 405 GLU A CA  1 
ATOM   3183  C  C   . GLU A 1 405 ? 2.626   -5.724  4.083   1.00 24.95  ? 405 GLU A C   1 
ATOM   3184  O  O   . GLU A 1 405 ? 3.155   -6.757  4.492   1.00 27.81  ? 405 GLU A O   1 
ATOM   3185  C  CB  . GLU A 1 405 ? 0.395   -6.592  4.877   1.00 22.02  ? 405 GLU A CB  1 
ATOM   3186  C  CG  . GLU A 1 405 ? -0.941  -6.099  5.417   1.00 20.39  ? 405 GLU A CG  1 
ATOM   3187  C  CD  . GLU A 1 405 ? -1.416  -6.907  6.614   1.00 25.93  ? 405 GLU A CD  1 
ATOM   3188  O  OE1 . GLU A 1 405 ? -0.843  -7.982  6.881   1.00 25.56  ? 405 GLU A OE1 1 
ATOM   3189  O  OE2 . GLU A 1 405 ? -2.340  -6.458  7.314   1.00 28.37  ? 405 GLU A OE2 1 
ATOM   3190  N  N   . TYR A 1 406 ? 3.330   -4.680  3.665   1.00 19.34  ? 406 TYR A N   1 
ATOM   3191  C  CA  . TYR A 1 406 ? 4.774   -4.633  3.853   1.00 20.03  ? 406 TYR A CA  1 
ATOM   3192  C  C   . TYR A 1 406 ? 5.119   -4.758  5.323   1.00 24.07  ? 406 TYR A C   1 
ATOM   3193  O  O   . TYR A 1 406 ? 4.549   -4.060  6.161   1.00 24.44  ? 406 TYR A O   1 
ATOM   3194  C  CB  . TYR A 1 406 ? 5.338   -3.307  3.336   1.00 24.86  ? 406 TYR A CB  1 
ATOM   3195  C  CG  . TYR A 1 406 ? 6.814   -3.129  3.637   1.00 23.23  ? 406 TYR A CG  1 
ATOM   3196  C  CD1 . TYR A 1 406 ? 7.747   -4.004  3.106   1.00 24.59  ? 406 TYR A CD1 1 
ATOM   3197  C  CD2 . TYR A 1 406 ? 7.276   -2.093  4.435   1.00 24.55  ? 406 TYR A CD2 1 
ATOM   3198  C  CE1 . TYR A 1 406 ? 9.089   -3.847  3.340   1.00 26.73  ? 406 TYR A CE1 1 
ATOM   3199  C  CE2 . TYR A 1 406 ? 8.631   -1.929  4.683   1.00 23.42  ? 406 TYR A CE2 1 
ATOM   3200  C  CZ  . TYR A 1 406 ? 9.534   -2.819  4.140   1.00 27.17  ? 406 TYR A CZ  1 
ATOM   3201  O  OH  . TYR A 1 406 ? 10.896  -2.697  4.359   1.00 27.62  ? 406 TYR A OH  1 
ATOM   3202  N  N   . GLU A 1 407 ? 6.098   -5.598  5.636   1.00 26.15  ? 407 GLU A N   1 
ATOM   3203  C  CA  . GLU A 1 407 ? 6.486   -5.782  7.029   1.00 24.10  ? 407 GLU A CA  1 
ATOM   3204  C  C   . GLU A 1 407 ? 7.983   -6.017  7.130   1.00 23.84  ? 407 GLU A C   1 
ATOM   3205  O  O   . GLU A 1 407 ? 8.443   -6.852  7.909   1.00 26.11  ? 407 GLU A O   1 
ATOM   3206  C  CB  . GLU A 1 407 ? 5.705   -6.927  7.683   1.00 26.59  ? 407 GLU A CB  1 
ATOM   3207  C  CG  . GLU A 1 407 ? 5.441   -6.662  9.159   1.00 32.03  ? 407 GLU A CG  1 
ATOM   3208  C  CD  . GLU A 1 407 ? 4.775   -7.806  9.863   1.00 38.23  ? 407 GLU A CD  1 
ATOM   3209  O  OE1 . GLU A 1 407 ? 5.319   -8.932  9.808   1.00 37.09  ? 407 GLU A OE1 1 
ATOM   3210  O  OE2 . GLU A 1 407 ? 3.699   -7.573  10.467  1.00 34.34  ? 407 GLU A OE2 1 
ATOM   3211  N  N   . GLY A 1 408 ? 8.757   -5.309  6.323   1.00 28.86  ? 408 GLY A N   1 
ATOM   3212  C  CA  . GLY A 1 408 ? 10.198  -5.406  6.362   1.00 26.99  ? 408 GLY A CA  1 
ATOM   3213  C  C   . GLY A 1 408 ? 10.776  -4.344  7.260   1.00 25.73  ? 408 GLY A C   1 
ATOM   3214  O  O   . GLY A 1 408 ? 10.079  -3.742  8.074   1.00 27.60  ? 408 GLY A O   1 
ATOM   3215  N  N   . GLU A 1 409 ? 12.072  -4.102  7.101   1.00 31.14  ? 409 GLU A N   1 
ATOM   3216  C  CA  . GLU A 1 409 ? 12.722  -3.059  7.872   1.00 30.16  ? 409 GLU A CA  1 
ATOM   3217  C  C   . GLU A 1 409 ? 11.964  -1.747  7.704   1.00 35.57  ? 409 GLU A C   1 
ATOM   3218  O  O   . GLU A 1 409 ? 11.633  -1.353  6.583   1.00 30.04  ? 409 GLU A O   1 
ATOM   3219  C  CB  . GLU A 1 409 ? 14.177  -2.913  7.419   1.00 34.86  ? 409 GLU A CB  1 
ATOM   3220  C  CG  . GLU A 1 409 ? 15.019  -4.156  7.691   1.00 41.95  ? 409 GLU A CG  1 
ATOM   3221  C  CD  . GLU A 1 409 ? 15.142  -4.470  9.175   1.00 47.34  ? 409 GLU A CD  1 
ATOM   3222  O  OE1 . GLU A 1 409 ? 16.089  -3.960  9.806   1.00 50.04  ? 409 GLU A OE1 1 
ATOM   3223  O  OE2 . GLU A 1 409 ? 14.286  -5.217  9.712   1.00 48.02  ? 409 GLU A OE2 1 
ATOM   3224  N  N   . ARG A 1 410 ? 11.640  -1.103  8.826   1.00 29.77  ? 410 ARG A N   1 
ATOM   3225  C  CA  . ARG A 1 410 ? 10.910  0.166   8.807   1.00 27.42  ? 410 ARG A CA  1 
ATOM   3226  C  C   . ARG A 1 410 ? 11.863  1.353   8.716   1.00 27.93  ? 410 ARG A C   1 
ATOM   3227  O  O   . ARG A 1 410 ? 11.771  2.313   9.480   1.00 29.08  ? 410 ARG A O   1 
ATOM   3228  C  CB  . ARG A 1 410 ? 10.027  0.275   10.037  1.00 27.13  ? 410 ARG A CB  1 
ATOM   3229  C  CG  . ARG A 1 410 ? 9.173   -0.948  10.270  1.00 36.92  ? 410 ARG A CG  1 
ATOM   3230  C  CD  . ARG A 1 410 ? 7.981   -0.858  9.403   1.00 29.33  ? 410 ARG A CD  1 
ATOM   3231  N  NE  . ARG A 1 410 ? 7.057   -1.971  9.551   1.00 25.88  ? 410 ARG A NE  1 
ATOM   3232  C  CZ  . ARG A 1 410 ? 6.075   -2.178  8.694   1.00 26.31  ? 410 ARG A CZ  1 
ATOM   3233  N  NH1 . ARG A 1 410 ? 5.935   -1.419  7.619   1.00 23.23  ? 410 ARG A NH1 1 
ATOM   3234  N  NH2 . ARG A 1 410 ? 5.208   -3.160  8.917   1.00 29.51  ? 410 ARG A NH2 1 
ATOM   3235  N  N   . GLU A 1 411 ? 12.822  1.258   7.808   1.00 24.13  ? 411 GLU A N   1 
ATOM   3236  C  CA  . GLU A 1 411 ? 13.664  2.394   7.492   1.00 31.67  ? 411 GLU A CA  1 
ATOM   3237  C  C   . GLU A 1 411 ? 12.807  3.457   6.811   1.00 32.14  ? 411 GLU A C   1 
ATOM   3238  O  O   . GLU A 1 411 ? 11.933  3.122   6.004   1.00 31.97  ? 411 GLU A O   1 
ATOM   3239  C  CB  . GLU A 1 411 ? 14.828  1.977   6.587   1.00 29.82  ? 411 GLU A CB  1 
ATOM   3240  C  CG  . GLU A 1 411 ? 16.148  2.666   6.915   1.00 37.96  ? 411 GLU A CG  1 
ATOM   3241  C  CD  . GLU A 1 411 ? 16.491  2.624   8.411   1.00 44.67  ? 411 GLU A CD  1 
ATOM   3242  O  OE1 . GLU A 1 411 ? 17.136  3.577   8.905   1.00 58.26  ? 411 GLU A OE1 1 
ATOM   3243  O  OE2 . GLU A 1 411 ? 16.150  1.637   9.098   1.00 49.38  ? 411 GLU A OE2 1 
ATOM   3244  N  N   . PRO A 1 412 ? 12.977  4.723   7.170   1.00 31.35  ? 412 PRO A N   1 
ATOM   3245  C  CA  . PRO A 1 412 ? 12.130  5.777   6.603   1.00 27.00  ? 412 PRO A CA  1 
ATOM   3246  C  C   . PRO A 1 412 ? 12.120  5.748   5.085   1.00 25.15  ? 412 PRO A C   1 
ATOM   3247  O  O   . PRO A 1 412 ? 13.163  5.614   4.439   1.00 27.87  ? 412 PRO A O   1 
ATOM   3248  C  CB  . PRO A 1 412 ? 12.770  7.052   7.151   1.00 26.99  ? 412 PRO A CB  1 
ATOM   3249  C  CG  . PRO A 1 412 ? 13.233  6.581   8.537   1.00 26.32  ? 412 PRO A CG  1 
ATOM   3250  C  CD  . PRO A 1 412 ? 13.781  5.209   8.305   1.00 30.96  ? 412 PRO A CD  1 
ATOM   3251  N  N   . TRP A 1 413 ? 10.911  5.832   4.529   1.00 27.95  ? 413 TRP A N   1 
ATOM   3252  C  CA  . TRP A 1 413 ? 10.611  5.813   3.095   1.00 24.87  ? 413 TRP A CA  1 
ATOM   3253  C  C   . TRP A 1 413 ? 10.794  4.426   2.480   1.00 24.89  ? 413 TRP A C   1 
ATOM   3254  O  O   . TRP A 1 413 ? 10.304  4.199   1.375   1.00 28.44  ? 413 TRP A O   1 
ATOM   3255  C  CB  . TRP A 1 413 ? 11.438  6.876   2.302   1.00 23.07  ? 413 TRP A CB  1 
ATOM   3256  C  CG  . TRP A 1 413 ? 11.064  8.255   2.716   1.00 26.46  ? 413 TRP A CG  1 
ATOM   3257  C  CD1 . TRP A 1 413 ? 9.927   8.932   2.384   1.00 30.28  ? 413 TRP A CD1 1 
ATOM   3258  C  CD2 . TRP A 1 413 ? 11.801  9.115   3.583   1.00 25.28  ? 413 TRP A CD2 1 
ATOM   3259  N  NE1 . TRP A 1 413 ? 9.907   10.168  3.004   1.00 26.81  ? 413 TRP A NE1 1 
ATOM   3260  C  CE2 . TRP A 1 413 ? 11.050  10.302  3.739   1.00 26.80  ? 413 TRP A CE2 1 
ATOM   3261  C  CE3 . TRP A 1 413 ? 13.034  9.006   4.238   1.00 28.15  ? 413 TRP A CE3 1 
ATOM   3262  C  CZ2 . TRP A 1 413 ? 11.490  11.372  4.526   1.00 26.53  ? 413 TRP A CZ2 1 
ATOM   3263  C  CZ3 . TRP A 1 413 ? 13.458  10.062  5.032   1.00 25.00  ? 413 TRP A CZ3 1 
ATOM   3264  C  CH2 . TRP A 1 413 ? 12.683  11.224  5.172   1.00 26.08  ? 413 TRP A CH2 1 
ATOM   3265  N  N   . ARG A 1 414 ? 11.455  3.478   3.156   1.00 23.10  ? 414 ARG A N   1 
ATOM   3266  C  CA  . ARG A 1 414 ? 11.682  2.198   2.484   1.00 27.40  ? 414 ARG A CA  1 
ATOM   3267  C  C   . ARG A 1 414 ? 10.381  1.585   1.953   1.00 26.97  ? 414 ARG A C   1 
ATOM   3268  O  O   . ARG A 1 414 ? 10.337  1.088   0.822   1.00 23.84  ? 414 ARG A O   1 
ATOM   3269  C  CB  . ARG A 1 414 ? 12.394  1.209   3.401   1.00 30.82  ? 414 ARG A CB  1 
ATOM   3270  C  CG  . ARG A 1 414 ? 12.758  -0.052  2.637   1.00 32.64  ? 414 ARG A CG  1 
ATOM   3271  C  CD  . ARG A 1 414 ? 13.559  -1.052  3.433   1.00 30.00  ? 414 ARG A CD  1 
ATOM   3272  N  NE  . ARG A 1 414 ? 14.412  -1.806  2.523   1.00 36.04  ? 414 ARG A NE  1 
ATOM   3273  C  CZ  . ARG A 1 414 ? 14.196  -3.059  2.152   1.00 36.71  ? 414 ARG A CZ  1 
ATOM   3274  N  NH1 . ARG A 1 414 ? 13.173  -3.761  2.630   1.00 32.94  ? 414 ARG A NH1 1 
ATOM   3275  N  NH2 . ARG A 1 414 ? 15.028  -3.624  1.282   1.00 36.54  ? 414 ARG A NH2 1 
ATOM   3276  N  N   . SER A 1 415 ? 9.303   1.648   2.736   1.00 23.42  ? 415 SER A N   1 
ATOM   3277  C  CA  . SER A 1 415 ? 8.069   0.945   2.387   1.00 26.60  ? 415 SER A CA  1 
ATOM   3278  C  C   . SER A 1 415 ? 7.458   1.392   1.056   1.00 26.31  ? 415 SER A C   1 
ATOM   3279  O  O   . SER A 1 415 ? 6.657   0.647   0.474   1.00 28.40  ? 415 SER A O   1 
ATOM   3280  C  CB  . SER A 1 415 ? 7.038   1.153   3.469   1.00 24.83  ? 415 SER A CB  1 
ATOM   3281  O  OG  . SER A 1 415 ? 6.708   2.519   3.531   1.00 24.18  ? 415 SER A OG  1 
ATOM   3282  N  N   . ILE A 1 416 ? 7.798   2.581   0.559   1.00 30.13  ? 416 ILE A N   1 
ATOM   3283  C  CA  . ILE A 1 416 ? 7.162   3.058   -0.668  1.00 27.08  ? 416 ILE A CA  1 
ATOM   3284  C  C   . ILE A 1 416 ? 7.648   2.255   -1.861  1.00 26.03  ? 416 ILE A C   1 
ATOM   3285  O  O   . ILE A 1 416 ? 6.843   1.734   -2.641  1.00 28.17  ? 416 ILE A O   1 
ATOM   3286  C  CB  . ILE A 1 416 ? 7.414   4.558   -0.870  1.00 22.68  ? 416 ILE A CB  1 
ATOM   3287  C  CG1 . ILE A 1 416 ? 6.568   5.357   0.124   1.00 29.09  ? 416 ILE A CG1 1 
ATOM   3288  C  CG2 . ILE A 1 416 ? 7.080   4.963   -2.279  1.00 22.38  ? 416 ILE A CG2 1 
ATOM   3289  C  CD1 . ILE A 1 416 ? 7.094   6.728   0.320   1.00 25.67  ? 416 ILE A CD1 1 
ATOM   3290  N  N   . GLU A 1 417 ? 8.975   2.157   -2.019  1.00 27.18  ? 417 GLU A N   1 
ATOM   3291  C  CA  . GLU A 1 417 ? 9.564   1.317   -3.056  1.00 25.34  ? 417 GLU A CA  1 
ATOM   3292  C  C   . GLU A 1 417 ? 9.143   -0.138  -2.894  1.00 27.52  ? 417 GLU A C   1 
ATOM   3293  O  O   . GLU A 1 417 ? 8.886   -0.842  -3.883  1.00 27.14  ? 417 GLU A O   1 
ATOM   3294  C  CB  . GLU A 1 417 ? 11.092  1.431   -3.009  1.00 25.72  ? 417 GLU A CB  1 
ATOM   3295  C  CG  . GLU A 1 417 ? 11.711  2.226   -4.128  1.00 32.61  ? 417 GLU A CG  1 
ATOM   3296  C  CD  . GLU A 1 417 ? 11.311  1.727   -5.521  1.00 33.50  ? 417 GLU A CD  1 
ATOM   3297  O  OE1 . GLU A 1 417 ? 11.854  0.697   -5.984  1.00 33.77  ? 417 GLU A OE1 1 
ATOM   3298  O  OE2 . GLU A 1 417 ? 10.451  2.378   -6.154  1.00 33.02  ? 417 GLU A OE2 1 
ATOM   3299  N  N   . GLN A 1 418 ? 9.078   -0.610  -1.649  1.00 27.53  ? 418 GLN A N   1 
ATOM   3300  C  CA  . GLN A 1 418 ? 8.795   -2.019  -1.402  1.00 25.39  ? 418 GLN A CA  1 
ATOM   3301  C  C   . GLN A 1 418 ? 7.391   -2.385  -1.865  1.00 28.04  ? 418 GLN A C   1 
ATOM   3302  O  O   . GLN A 1 418 ? 7.209   -3.342  -2.625  1.00 28.28  ? 418 GLN A O   1 
ATOM   3303  C  CB  . GLN A 1 418 ? 9.009   -2.322  0.077   1.00 22.58  ? 418 GLN A CB  1 
ATOM   3304  C  CG  . GLN A 1 418 ? 10.487  -2.398  0.419   1.00 26.63  ? 418 GLN A CG  1 
ATOM   3305  C  CD  . GLN A 1 418 ? 11.190  -3.516  -0.327  1.00 31.33  ? 418 GLN A CD  1 
ATOM   3306  O  OE1 . GLN A 1 418 ? 10.763  -4.658  -0.267  1.00 29.21  ? 418 GLN A OE1 1 
ATOM   3307  N  NE2 . GLN A 1 418 ? 12.256  -3.187  -1.050  1.00 26.24  ? 418 GLN A NE2 1 
ATOM   3308  N  N   . VAL A 1 419 ? 6.389   -1.599  -1.466  1.00 26.64  ? 419 VAL A N   1 
ATOM   3309  C  CA  . VAL A 1 419 ? 5.031   -1.856  -1.932  1.00 24.01  ? 419 VAL A CA  1 
ATOM   3310  C  C   . VAL A 1 419 ? 4.967   -1.829  -3.466  1.00 29.58  ? 419 VAL A C   1 
ATOM   3311  O  O   . VAL A 1 419 ? 4.328   -2.692  -4.084  1.00 23.10  ? 419 VAL A O   1 
ATOM   3312  C  CB  . VAL A 1 419 ? 4.067   -0.851  -1.287  1.00 21.53  ? 419 VAL A CB  1 
ATOM   3313  C  CG1 . VAL A 1 419 ? 2.697   -0.920  -1.908  1.00 29.84  ? 419 VAL A CG1 1 
ATOM   3314  C  CG2 . VAL A 1 419 ? 4.001   -1.086  0.243   1.00 26.77  ? 419 VAL A CG2 1 
ATOM   3315  N  N   . ARG A 1 420 ? 5.645   -0.851  -4.098  1.00 21.77  ? 420 ARG A N   1 
ATOM   3316  C  CA  . ARG A 1 420 ? 5.664   -0.752  -5.560  1.00 23.27  ? 420 ARG A CA  1 
ATOM   3317  C  C   . ARG A 1 420 ? 6.267   -2.006  -6.181  1.00 28.48  ? 420 ARG A C   1 
ATOM   3318  O  O   . ARG A 1 420 ? 5.769   -2.523  -7.186  1.00 25.27  ? 420 ARG A O   1 
ATOM   3319  C  CB  . ARG A 1 420 ? 6.481   0.465   -6.018  1.00 27.45  ? 420 ARG A CB  1 
ATOM   3320  C  CG  . ARG A 1 420 ? 5.872   1.876   -5.784  1.00 24.29  ? 420 ARG A CG  1 
ATOM   3321  C  CD  . ARG A 1 420 ? 6.785   2.985   -6.313  1.00 28.73  ? 420 ARG A CD  1 
ATOM   3322  N  NE  . ARG A 1 420 ? 6.642   3.258   -7.747  1.00 24.23  ? 420 ARG A NE  1 
ATOM   3323  C  CZ  . ARG A 1 420 ? 5.621   3.896   -8.303  1.00 21.69  ? 420 ARG A CZ  1 
ATOM   3324  N  NH1 . ARG A 1 420 ? 4.566   4.265   -7.595  1.00 19.37  ? 420 ARG A NH1 1 
ATOM   3325  N  NH2 . ARG A 1 420 ? 5.660   4.172   -9.612  1.00 28.20  ? 420 ARG A NH2 1 
ATOM   3326  N  N   . ARG A 1 421 ? 7.361   -2.489  -5.610  1.00 26.18  ? 421 ARG A N   1 
ATOM   3327  C  CA  . ARG A 1 421 ? 7.984   -3.686  -6.141  1.00 25.86  ? 421 ARG A CA  1 
ATOM   3328  C  C   . ARG A 1 421 ? 7.051   -4.878  -6.034  1.00 28.78  ? 421 ARG A C   1 
ATOM   3329  O  O   . ARG A 1 421 ? 6.961   -5.686  -6.963  1.00 28.65  ? 421 ARG A O   1 
ATOM   3330  C  CB  . ARG A 1 421 ? 9.282   -3.955  -5.408  1.00 20.33  ? 421 ARG A CB  1 
ATOM   3331  C  CG  . ARG A 1 421 ? 10.392  -3.164  -5.948  1.00 26.62  ? 421 ARG A CG  1 
ATOM   3332  C  CD  . ARG A 1 421 ? 11.471  -3.109  -4.955  1.00 26.98  ? 421 ARG A CD  1 
ATOM   3333  N  NE  . ARG A 1 421 ? 12.353  -1.995  -5.214  1.00 24.74  ? 421 ARG A NE  1 
ATOM   3334  C  CZ  . ARG A 1 421 ? 13.626  -1.977  -4.855  1.00 32.87  ? 421 ARG A CZ  1 
ATOM   3335  N  NH1 . ARG A 1 421 ? 14.165  -2.988  -4.185  1.00 30.67  ? 421 ARG A NH1 1 
ATOM   3336  N  NH2 . ARG A 1 421 ? 14.370  -0.922  -5.174  1.00 28.86  ? 421 ARG A NH2 1 
ATOM   3337  N  N   . GLN A 1 422 ? 6.336   -4.999  -4.918  1.00 25.83  ? 422 GLN A N   1 
ATOM   3338  C  CA  . GLN A 1 422 ? 5.420   -6.122  -4.784  1.00 29.85  ? 422 GLN A CA  1 
ATOM   3339  C  C   . GLN A 1 422 ? 4.324   -6.066  -5.840  1.00 28.82  ? 422 GLN A C   1 
ATOM   3340  O  O   . GLN A 1 422 ? 3.969   -7.092  -6.428  1.00 31.23  ? 422 GLN A O   1 
ATOM   3341  C  CB  . GLN A 1 422 ? 4.820   -6.174  -3.378  1.00 24.46  ? 422 GLN A CB  1 
ATOM   3342  C  CG  . GLN A 1 422 ? 3.930   -7.408  -3.190  1.00 27.03  ? 422 GLN A CG  1 
ATOM   3343  C  CD  . GLN A 1 422 ? 2.987   -7.296  -2.017  1.00 28.90  ? 422 GLN A CD  1 
ATOM   3344  O  OE1 . GLN A 1 422 ? 2.409   -6.238  -1.760  1.00 35.07  ? 422 GLN A OE1 1 
ATOM   3345  N  NE2 . GLN A 1 422 ? 2.843   -8.386  -1.277  1.00 26.75  ? 422 GLN A NE2 1 
ATOM   3346  N  N   . HIS A 1 423 ? 3.794   -4.875  -6.121  1.00 31.31  ? 423 HIS A N   1 
ATOM   3347  C  CA  . HIS A 1 423 ? 2.710   -4.798  -7.091  1.00 29.81  ? 423 HIS A CA  1 
ATOM   3348  C  C   . HIS A 1 423 ? 3.219   -5.081  -8.494  1.00 26.81  ? 423 HIS A C   1 
ATOM   3349  O  O   . HIS A 1 423 ? 2.555   -5.770  -9.269  1.00 28.87  ? 423 HIS A O   1 
ATOM   3350  C  CB  . HIS A 1 423 ? 2.007   -3.442  -7.011  1.00 30.40  ? 423 HIS A CB  1 
ATOM   3351  C  CG  . HIS A 1 423 ? 0.988   -3.368  -5.916  1.00 25.36  ? 423 HIS A CG  1 
ATOM   3352  N  ND1 . HIS A 1 423 ? -0.367  -3.385  -6.153  1.00 27.38  ? 423 HIS A ND1 1 
ATOM   3353  C  CD2 . HIS A 1 423 ? 1.132   -3.300  -4.571  1.00 29.96  ? 423 HIS A CD2 1 
ATOM   3354  C  CE1 . HIS A 1 423 ? -1.020  -3.321  -5.005  1.00 29.04  ? 423 HIS A CE1 1 
ATOM   3355  N  NE2 . HIS A 1 423 ? -0.132  -3.269  -4.029  1.00 30.61  ? 423 HIS A NE2 1 
ATOM   3356  N  N   . SER A 1 424 ? 4.408   -4.589  -8.828  1.00 26.45  ? 424 SER A N   1 
ATOM   3357  C  CA  . SER A 1 424 ? 5.013   -4.959  -10.099 1.00 25.87  ? 424 SER A CA  1 
ATOM   3358  C  C   . SER A 1 424 ? 5.294   -6.459  -10.164 1.00 28.02  ? 424 SER A C   1 
ATOM   3359  O  O   . SER A 1 424 ? 5.049   -7.102  -11.188 1.00 26.38  ? 424 SER A O   1 
ATOM   3360  C  CB  . SER A 1 424 ? 6.300   -4.164  -10.308 1.00 26.57  ? 424 SER A CB  1 
ATOM   3361  O  OG  . SER A 1 424 ? 6.905   -4.549  -11.533 1.00 29.27  ? 424 SER A OG  1 
ATOM   3362  N  N   . LEU A 1 425 ? 5.823   -7.035  -9.084  1.00 31.69  ? 425 LEU A N   1 
ATOM   3363  C  CA  . LEU A 1 425 ? 6.086   -8.472  -9.069  1.00 28.54  ? 425 LEU A CA  1 
ATOM   3364  C  C   . LEU A 1 425 ? 4.816   -9.268  -9.296  1.00 27.53  ? 425 LEU A C   1 
ATOM   3365  O  O   . LEU A 1 425 ? 4.741   -10.103 -10.206 1.00 31.13  ? 425 LEU A O   1 
ATOM   3366  C  CB  . LEU A 1 425 ? 6.716   -8.876  -7.739  1.00 26.34  ? 425 LEU A CB  1 
ATOM   3367  C  CG  . LEU A 1 425 ? 7.108   -10.348 -7.630  1.00 30.27  ? 425 LEU A CG  1 
ATOM   3368  C  CD1 . LEU A 1 425 ? 7.807   -10.796 -8.914  1.00 28.22  ? 425 LEU A CD1 1 
ATOM   3369  C  CD2 . LEU A 1 425 ? 8.009   -10.583 -6.389  1.00 26.05  ? 425 LEU A CD2 1 
ATOM   3370  N  N   . ILE A 1 426 ? 3.805   -9.022  -8.473  1.00 24.05  ? 426 ILE A N   1 
ATOM   3371  C  CA  . ILE A 1 426 ? 2.628   -9.875  -8.464  1.00 29.98  ? 426 ILE A CA  1 
ATOM   3372  C  C   . ILE A 1 426 ? 1.846   -9.754  -9.764  1.00 32.99  ? 426 ILE A C   1 
ATOM   3373  O  O   . ILE A 1 426 ? 1.313   -10.746 -10.272 1.00 30.17  ? 426 ILE A O   1 
ATOM   3374  C  CB  . ILE A 1 426 ? 1.753   -9.554  -7.243  1.00 30.19  ? 426 ILE A CB  1 
ATOM   3375  C  CG1 . ILE A 1 426 ? 2.410   -10.104 -5.990  1.00 30.04  ? 426 ILE A CG1 1 
ATOM   3376  C  CG2 . ILE A 1 426 ? 0.374   -10.186 -7.376  1.00 31.77  ? 426 ILE A CG2 1 
ATOM   3377  C  CD1 . ILE A 1 426 ? 1.516   -9.999  -4.809  1.00 29.50  ? 426 ILE A CD1 1 
ATOM   3378  N  N   . ARG A 1 427 ? 1.740   -8.551  -10.323 1.00 28.84  ? 427 ARG A N   1 
ATOM   3379  C  CA  . ARG A 1 427 ? 0.927   -8.433  -11.529 1.00 30.97  ? 427 ARG A CA  1 
ATOM   3380  C  C   . ARG A 1 427 ? 1.601   -9.126  -12.707 1.00 31.52  ? 427 ARG A C   1 
ATOM   3381  O  O   . ARG A 1 427 ? 0.939   -9.826  -13.479 1.00 29.22  ? 427 ARG A O   1 
ATOM   3382  C  CB  . ARG A 1 427 ? 0.622   -6.968  -11.816 1.00 30.06  ? 427 ARG A CB  1 
ATOM   3383  C  CG  . ARG A 1 427 ? -0.513  -6.463  -10.909 1.00 34.46  ? 427 ARG A CG  1 
ATOM   3384  C  CD  . ARG A 1 427 ? -0.550  -4.970  -10.823 1.00 30.59  ? 427 ARG A CD  1 
ATOM   3385  N  NE  . ARG A 1 427 ? -0.937  -4.375  -12.086 1.00 34.27  ? 427 ARG A NE  1 
ATOM   3386  C  CZ  . ARG A 1 427 ? -1.889  -3.463  -12.218 1.00 44.08  ? 427 ARG A CZ  1 
ATOM   3387  N  NH1 . ARG A 1 427 ? -2.639  -3.090  -11.185 1.00 43.33  ? 427 ARG A NH1 1 
ATOM   3388  N  NH2 . ARG A 1 427 ? -2.080  -2.897  -13.409 1.00 35.16  ? 427 ARG A NH2 1 
ATOM   3389  N  N   . GLN A 1 428 ? 2.924   -9.006  -12.814 1.00 24.70  ? 428 GLN A N   1 
ATOM   3390  C  CA  . GLN A 1 428 ? 3.658   -9.729  -13.842 1.00 27.31  ? 428 GLN A CA  1 
ATOM   3391  C  C   . GLN A 1 428 ? 3.483   -11.241 -13.712 1.00 31.61  ? 428 GLN A C   1 
ATOM   3392  O  O   . GLN A 1 428 ? 3.252   -11.927 -14.713 1.00 34.57  ? 428 GLN A O   1 
ATOM   3393  C  CB  . GLN A 1 428 ? 5.129   -9.351  -13.776 1.00 28.52  ? 428 GLN A CB  1 
ATOM   3394  C  CG  . GLN A 1 428 ? 5.411   -7.990  -14.337 1.00 25.37  ? 428 GLN A CG  1 
ATOM   3395  C  CD  . GLN A 1 428 ? 6.877   -7.663  -14.271 1.00 31.53  ? 428 GLN A CD  1 
ATOM   3396  O  OE1 . GLN A 1 428 ? 7.695   -8.327  -14.910 1.00 34.57  ? 428 GLN A OE1 1 
ATOM   3397  N  NE2 . GLN A 1 428 ? 7.226   -6.625  -13.506 1.00 31.17  ? 428 GLN A NE2 1 
ATOM   3398  N  N   . ILE A 1 429 ? 3.585   -11.786 -12.489 1.00 30.89  ? 429 ILE A N   1 
ATOM   3399  C  CA  . ILE A 1 429 ? 3.386   -13.229 -12.301 1.00 29.62  ? 429 ILE A CA  1 
ATOM   3400  C  C   . ILE A 1 429 ? 1.976   -13.636 -12.700 1.00 33.29  ? 429 ILE A C   1 
ATOM   3401  O  O   . ILE A 1 429 ? 1.776   -14.627 -13.416 1.00 33.92  ? 429 ILE A O   1 
ATOM   3402  C  CB  . ILE A 1 429 ? 3.691   -13.649 -10.858 1.00 29.93  ? 429 ILE A CB  1 
ATOM   3403  C  CG1 . ILE A 1 429 ? 5.192   -13.614 -10.615 1.00 30.10  ? 429 ILE A CG1 1 
ATOM   3404  C  CG2 . ILE A 1 429 ? 3.216   -15.064 -10.620 1.00 35.30  ? 429 ILE A CG2 1 
ATOM   3405  C  CD1 . ILE A 1 429 ? 5.529   -13.589 -9.150  1.00 32.05  ? 429 ILE A CD1 1 
ATOM   3406  N  N   . ALA A 1 430 ? 0.975   -12.881 -12.240 1.00 26.51  ? 430 ALA A N   1 
ATOM   3407  C  CA  . ALA A 1 430 ? -0.410  -13.156 -12.623 1.00 30.70  ? 430 ALA A CA  1 
ATOM   3408  C  C   . ALA A 1 430 ? -0.590  -13.217 -14.141 1.00 32.30  ? 430 ALA A C   1 
ATOM   3409  O  O   . ALA A 1 430 ? -1.376  -14.031 -14.653 1.00 28.22  ? 430 ALA A O   1 
ATOM   3410  C  CB  . ALA A 1 430 ? -1.342  -12.099 -12.025 1.00 29.70  ? 430 ALA A CB  1 
ATOM   3411  N  N   . ASP A 1 431 ? 0.133   -12.369 -14.879 1.00 30.67  ? 431 ASP A N   1 
ATOM   3412  C  CA  . ASP A 1 431 ? -0.038  -12.327 -16.329 1.00 27.17  ? 431 ASP A CA  1 
ATOM   3413  C  C   . ASP A 1 431 ? 0.613   -13.536 -16.996 1.00 33.22  ? 431 ASP A C   1 
ATOM   3414  O  O   . ASP A 1 431 ? 0.090   -14.060 -17.987 1.00 35.43  ? 431 ASP A O   1 
ATOM   3415  C  CB  . ASP A 1 431 ? 0.555   -11.035 -16.895 1.00 27.64  ? 431 ASP A CB  1 
ATOM   3416  C  CG  . ASP A 1 431 ? -0.404  -9.839  -16.817 1.00 28.36  ? 431 ASP A CG  1 
ATOM   3417  O  OD1 . ASP A 1 431 ? -1.493  -9.912  -16.198 1.00 30.65  ? 431 ASP A OD1 1 
ATOM   3418  O  OD2 . ASP A 1 431 ? -0.044  -8.794  -17.376 1.00 27.59  ? 431 ASP A OD2 1 
ATOM   3419  N  N   . ARG A 1 432 ? 1.766   -13.978 -16.488 1.00 34.09  ? 432 ARG A N   1 
ATOM   3420  C  CA  . ARG A 1 432 ? 2.400   -15.167 -17.046 1.00 37.29  ? 432 ARG A CA  1 
ATOM   3421  C  C   . ARG A 1 432 ? 1.642   -16.435 -16.673 1.00 35.65  ? 432 ARG A C   1 
ATOM   3422  O  O   . ARG A 1 432 ? 1.647   -17.407 -17.437 1.00 35.94  ? 432 ARG A O   1 
ATOM   3423  C  CB  . ARG A 1 432 ? 3.850   -15.246 -16.589 1.00 38.79  ? 432 ARG A CB  1 
ATOM   3424  C  CG  . ARG A 1 432 ? 4.755   -14.234 -17.284 1.00 41.18  ? 432 ARG A CG  1 
ATOM   3425  C  CD  . ARG A 1 432 ? 5.889   -13.956 -16.359 1.00 44.42  ? 432 ARG A CD  1 
ATOM   3426  N  NE  . ARG A 1 432 ? 6.532   -12.661 -16.526 1.00 48.87  ? 432 ARG A NE  1 
ATOM   3427  C  CZ  . ARG A 1 432 ? 7.205   -12.049 -15.559 1.00 45.61  ? 432 ARG A CZ  1 
ATOM   3428  N  NH1 . ARG A 1 432 ? 7.222   -12.528 -14.313 1.00 37.43  ? 432 ARG A NH1 1 
ATOM   3429  N  NH2 . ARG A 1 432 ? 7.882   -10.938 -15.845 1.00 37.21  ? 432 ARG A NH2 1 
ATOM   3430  N  N   . LEU A 1 433 ? 0.951   -16.436 -15.533 1.00 35.69  ? 433 LEU A N   1 
ATOM   3431  C  CA  . LEU A 1 433 ? 0.112   -17.585 -15.196 1.00 31.88  ? 433 LEU A CA  1 
ATOM   3432  C  C   . LEU A 1 433 ? -1.081  -17.709 -16.141 1.00 36.81  ? 433 LEU A C   1 
ATOM   3433  O  O   . LEU A 1 433 ? -1.620  -18.808 -16.329 1.00 40.11  ? 433 LEU A O   1 
ATOM   3434  C  CB  . LEU A 1 433 ? -0.366  -17.477 -13.758 1.00 32.24  ? 433 LEU A CB  1 
ATOM   3435  C  CG  . LEU A 1 433 ? 0.690   -17.546 -12.668 1.00 33.52  ? 433 LEU A CG  1 
ATOM   3436  C  CD1 . LEU A 1 433 ? -0.026  -17.622 -11.343 1.00 30.13  ? 433 LEU A CD1 1 
ATOM   3437  C  CD2 . LEU A 1 433 ? 1.595   -18.721 -12.862 1.00 32.88  ? 433 LEU A CD2 1 
ATOM   3438  N  N   . ALA A 1 434 ? -1.506  -16.599 -16.739 1.00 38.97  ? 434 ALA A N   1 
ATOM   3439  C  CA  . ALA A 1 434 ? -2.603  -16.634 -17.694 1.00 39.02  ? 434 ALA A CA  1 
ATOM   3440  C  C   . ALA A 1 434 ? -2.207  -17.339 -18.981 1.00 44.18  ? 434 ALA A C   1 
ATOM   3441  O  O   . ALA A 1 434 ? -3.085  -17.785 -19.727 1.00 44.49  ? 434 ALA A O   1 
ATOM   3442  C  CB  . ALA A 1 434 ? -3.082  -15.214 -17.985 1.00 39.21  ? 434 ALA A CB  1 
ATOM   3443  N  N   . GLU A 1 435 ? -0.911  -17.464 -19.243 1.00 44.93  ? 435 GLU A N   1 
ATOM   3444  C  CA  . GLU A 1 435 ? -0.419  -18.191 -20.401 1.00 42.55  ? 435 GLU A CA  1 
ATOM   3445  C  C   . GLU A 1 435 ? 0.002   -19.607 -20.032 1.00 45.33  ? 435 GLU A C   1 
ATOM   3446  O  O   . GLU A 1 435 ? -0.790  -20.546 -20.143 1.00 47.04  ? 435 GLU A O   1 
ATOM   3447  C  CB  . GLU A 1 435 ? 0.740   -17.426 -21.018 1.00 44.39  ? 435 GLU A CB  1 
ATOM   3448  C  CG  . GLU A 1 435 ? 0.574   -15.931 -20.863 1.00 40.90  ? 435 GLU A CG  1 
ATOM   3449  C  CD  . GLU A 1 435 ? 1.888   -15.202 -20.909 1.00 40.46  ? 435 GLU A CD  1 
ATOM   3450  O  OE1 . GLU A 1 435 ? 2.907   -15.805 -20.495 1.00 45.51  ? 435 GLU A OE1 1 
ATOM   3451  O  OE2 . GLU A 1 435 ? 1.901   -14.022 -21.329 1.00 38.64  ? 435 GLU A OE2 1 
ATOM   3452  N  N   . MET B 1 1   ? 0.857   18.016  12.014  1.00 34.27  ? 1   MET B N   1 
ATOM   3453  C  CA  . MET B 1 1   ? 1.777   17.901  13.139  1.00 36.18  ? 1   MET B CA  1 
ATOM   3454  C  C   . MET B 1 1   ? 2.455   16.557  13.214  1.00 37.98  ? 1   MET B C   1 
ATOM   3455  O  O   . MET B 1 1   ? 2.249   15.767  14.149  1.00 40.52  ? 1   MET B O   1 
ATOM   3456  C  CB  . MET B 1 1   ? 1.068   18.208  14.450  1.00 40.14  ? 1   MET B CB  1 
ATOM   3457  C  CG  . MET B 1 1   ? 0.781   19.682  14.627  1.00 35.40  ? 1   MET B CG  1 
ATOM   3458  S  SD  . MET B 1 1   ? 2.021   20.424  15.723  1.00 43.62  ? 1   MET B SD  1 
ATOM   3459  C  CE  . MET B 1 1   ? 1.877   19.433  17.208  1.00 35.35  ? 1   MET B CE  1 
ATOM   3460  N  N   . LEU B 1 2   ? 3.309   16.325  12.232  1.00 28.44  ? 2   LEU B N   1 
ATOM   3461  C  CA  . LEU B 1 2   ? 4.037   15.073  12.176  1.00 29.96  ? 2   LEU B CA  1 
ATOM   3462  C  C   . LEU B 1 2   ? 4.876   14.896  13.428  1.00 32.28  ? 2   LEU B C   1 
ATOM   3463  O  O   . LEU B 1 2   ? 5.230   15.861  14.114  1.00 26.20  ? 2   LEU B O   1 
ATOM   3464  C  CB  . LEU B 1 2   ? 4.927   15.039  10.940  1.00 29.36  ? 2   LEU B CB  1 
ATOM   3465  C  CG  . LEU B 1 2   ? 4.135   15.251  9.652   1.00 31.42  ? 2   LEU B CG  1 
ATOM   3466  C  CD1 . LEU B 1 2   ? 5.043   15.859  8.625   1.00 25.67  ? 2   LEU B CD1 1 
ATOM   3467  C  CD2 . LEU B 1 2   ? 3.518   13.930  9.148   1.00 28.15  ? 2   LEU B CD2 1 
ATOM   3468  N  N   . LEU B 1 3   ? 5.202   13.638  13.714  1.00 28.10  ? 3   LEU B N   1 
ATOM   3469  C  CA  . LEU B 1 3   ? 6.043   13.260  14.840  1.00 23.13  ? 3   LEU B CA  1 
ATOM   3470  C  C   . LEU B 1 3   ? 7.445   12.907  14.353  1.00 25.19  ? 3   LEU B C   1 
ATOM   3471  O  O   . LEU B 1 3   ? 7.633   12.470  13.211  1.00 22.95  ? 3   LEU B O   1 
ATOM   3472  C  CB  . LEU B 1 3   ? 5.438   12.050  15.566  1.00 24.67  ? 3   LEU B CB  1 
ATOM   3473  C  CG  . LEU B 1 3   ? 4.049   12.336  16.105  1.00 25.22  ? 3   LEU B CG  1 
ATOM   3474  C  CD1 . LEU B 1 3   ? 3.403   11.044  16.593  1.00 26.71  ? 3   LEU B CD1 1 
ATOM   3475  C  CD2 . LEU B 1 3   ? 4.143   13.378  17.215  1.00 24.07  ? 3   LEU B CD2 1 
ATOM   3476  N  N   . GLU B 1 4   ? 8.427   13.075  15.235  1.00 25.96  ? 4   GLU B N   1 
ATOM   3477  C  CA  . GLU B 1 4   ? 9.796   12.694  14.903  1.00 24.36  ? 4   GLU B CA  1 
ATOM   3478  C  C   . GLU B 1 4   ? 9.952   11.175  14.951  1.00 28.47  ? 4   GLU B C   1 
ATOM   3479  O  O   . GLU B 1 4   ? 9.229   10.471  15.674  1.00 26.98  ? 4   GLU B O   1 
ATOM   3480  C  CB  . GLU B 1 4   ? 10.781  13.383  15.852  1.00 25.34  ? 4   GLU B CB  1 
ATOM   3481  C  CG  . GLU B 1 4   ? 10.461  14.915  16.068  1.00 27.63  ? 4   GLU B CG  1 
ATOM   3482  C  CD  . GLU B 1 4   ? 10.998  15.504  17.413  1.00 26.27  ? 4   GLU B CD  1 
ATOM   3483  O  OE1 . GLU B 1 4   ? 12.086  15.072  17.877  1.00 22.57  ? 4   GLU B OE1 1 
ATOM   3484  O  OE2 . GLU B 1 4   ? 10.314  16.382  18.001  1.00 27.22  ? 4   GLU B OE2 1 
ATOM   3485  N  N   . ARG B 1 5   ? 10.908  10.674  14.159  1.00 27.11  ? 5   ARG B N   1 
ATOM   3486  C  CA  . ARG B 1 5   ? 11.072  9.233   13.972  1.00 27.36  ? 5   ARG B CA  1 
ATOM   3487  C  C   . ARG B 1 5   ? 11.485  8.527   15.263  1.00 27.95  ? 5   ARG B C   1 
ATOM   3488  O  O   . ARG B 1 5   ? 10.909  7.489   15.625  1.00 28.03  ? 5   ARG B O   1 
ATOM   3489  C  CB  . ARG B 1 5   ? 12.097  8.962   12.883  1.00 27.02  ? 5   ARG B CB  1 
ATOM   3490  C  CG  . ARG B 1 5   ? 12.053  7.524   12.344  1.00 29.43  ? 5   ARG B CG  1 
ATOM   3491  C  CD  . ARG B 1 5   ? 10.711  7.239   11.653  1.00 27.58  ? 5   ARG B CD  1 
ATOM   3492  N  NE  . ARG B 1 5   ? 10.703  6.002   10.868  1.00 22.66  ? 5   ARG B NE  1 
ATOM   3493  C  CZ  . ARG B 1 5   ? 10.119  5.890   9.682   1.00 24.84  ? 5   ARG B CZ  1 
ATOM   3494  N  NH1 . ARG B 1 5   ? 9.543   6.927   9.092   1.00 24.03  ? 5   ARG B NH1 1 
ATOM   3495  N  NH2 . ARG B 1 5   ? 10.122  4.712   9.062   1.00 30.74  ? 5   ARG B NH2 1 
ATOM   3496  N  N   . ASP B 1 6   ? 12.516  9.035   15.935  1.00 27.33  ? 6   ASP B N   1 
ATOM   3497  C  CA  . ASP B 1 6   ? 12.844  8.553   17.276  1.00 30.82  ? 6   ASP B CA  1 
ATOM   3498  C  C   . ASP B 1 6   ? 11.583  8.498   18.116  1.00 25.38  ? 6   ASP B C   1 
ATOM   3499  O  O   . ASP B 1 6   ? 10.715  9.369   18.009  1.00 26.34  ? 6   ASP B O   1 
ATOM   3500  C  CB  . ASP B 1 6   ? 13.865  9.463   17.968  1.00 25.85  ? 6   ASP B CB  1 
ATOM   3501  C  CG  . ASP B 1 6   ? 15.189  9.537   17.226  1.00 30.46  ? 6   ASP B CG  1 
ATOM   3502  O  OD1 . ASP B 1 6   ? 15.523  8.595   16.466  1.00 33.98  ? 6   ASP B OD1 1 
ATOM   3503  O  OD2 . ASP B 1 6   ? 15.897  10.552  17.398  1.00 32.95  ? 6   ASP B OD2 1 
ATOM   3504  N  N   . LEU B 1 7   ? 11.464  7.449   18.936  1.00 26.14  ? 7   LEU B N   1 
ATOM   3505  C  CA  . LEU B 1 7   ? 10.270  7.343   19.760  1.00 24.33  ? 7   LEU B CA  1 
ATOM   3506  C  C   . LEU B 1 7   ? 10.233  8.469   20.790  1.00 25.63  ? 7   LEU B C   1 
ATOM   3507  O  O   . LEU B 1 7   ? 9.168   9.027   21.073  1.00 25.50  ? 7   LEU B O   1 
ATOM   3508  C  CB  . LEU B 1 7   ? 10.199  5.968   20.431  1.00 24.03  ? 7   LEU B CB  1 
ATOM   3509  C  CG  . LEU B 1 7   ? 10.122  4.719   19.555  1.00 25.59  ? 7   LEU B CG  1 
ATOM   3510  C  CD1 . LEU B 1 7   ? 10.068  3.489   20.462  1.00 31.65  ? 7   LEU B CD1 1 
ATOM   3511  C  CD2 . LEU B 1 7   ? 8.894   4.746   18.644  1.00 22.77  ? 7   LEU B CD2 1 
ATOM   3512  N  N   . ILE B 1 8   ? 11.392  8.848   21.321  1.00 25.52  ? 8   ILE B N   1 
ATOM   3513  C  CA  . ILE B 1 8   ? 11.486  9.993   22.217  1.00 22.04  ? 8   ILE B CA  1 
ATOM   3514  C  C   . ILE B 1 8   ? 11.584  11.249  21.357  1.00 26.75  ? 8   ILE B C   1 
ATOM   3515  O  O   . ILE B 1 8   ? 12.555  11.425  20.617  1.00 32.42  ? 8   ILE B O   1 
ATOM   3516  C  CB  . ILE B 1 8   ? 12.698  9.875   23.149  1.00 21.74  ? 8   ILE B CB  1 
ATOM   3517  C  CG1 . ILE B 1 8   ? 12.665  8.555   23.936  1.00 25.83  ? 8   ILE B CG1 1 
ATOM   3518  C  CG2 . ILE B 1 8   ? 12.756  11.080  24.079  1.00 24.17  ? 8   ILE B CG2 1 
ATOM   3519  C  CD1 . ILE B 1 8   ? 13.984  8.249   24.654  1.00 26.41  ? 8   ILE B CD1 1 
ATOM   3520  N  N   . GLN B 1 9   ? 10.577  12.111  21.438  1.00 24.69  ? 9   GLN B N   1 
ATOM   3521  C  CA  . GLN B 1 9   ? 10.617  13.381  20.733  1.00 25.76  ? 9   GLN B CA  1 
ATOM   3522  C  C   . GLN B 1 9   ? 11.549  14.337  21.461  1.00 27.92  ? 9   GLN B C   1 
ATOM   3523  O  O   . GLN B 1 9   ? 11.676  14.275  22.683  1.00 23.43  ? 9   GLN B O   1 
ATOM   3524  C  CB  . GLN B 1 9   ? 9.223   13.990  20.649  1.00 19.63  ? 9   GLN B CB  1 
ATOM   3525  C  CG  . GLN B 1 9   ? 8.174   13.013  20.239  1.00 19.05  ? 9   GLN B CG  1 
ATOM   3526  C  CD  . GLN B 1 9   ? 8.263   12.639  18.762  1.00 21.82  ? 9   GLN B CD  1 
ATOM   3527  O  OE1 . GLN B 1 9   ? 7.860   13.409  17.877  1.00 23.28  ? 9   GLN B OE1 1 
ATOM   3528  N  NE2 . GLN B 1 9   ? 8.806   11.454  18.491  1.00 20.62  ? 9   GLN B NE2 1 
ATOM   3529  N  N   . SER B 1 10  ? 12.191  15.237  20.697  1.00 23.72  ? 10  SER B N   1 
ATOM   3530  C  CA  . SER B 1 10  ? 12.890  16.374  21.302  1.00 27.18  ? 10  SER B CA  1 
ATOM   3531  C  C   . SER B 1 10  ? 11.928  17.477  21.710  1.00 27.09  ? 10  SER B C   1 
ATOM   3532  O  O   . SER B 1 10  ? 12.079  18.071  22.780  1.00 24.40  ? 10  SER B O   1 
ATOM   3533  C  CB  . SER B 1 10  ? 13.922  16.942  20.333  1.00 20.04  ? 10  SER B CB  1 
ATOM   3534  O  OG  . SER B 1 10  ? 14.960  16.017  20.158  1.00 27.43  ? 10  SER B OG  1 
ATOM   3535  N  N   . VAL B 1 11  ? 10.949  17.793  20.862  1.00 26.80  ? 11  VAL B N   1 
ATOM   3536  C  CA  . VAL B 1 11  ? 9.987   18.820  21.221  1.00 23.52  ? 11  VAL B CA  1 
ATOM   3537  C  C   . VAL B 1 11  ? 9.162   18.348  22.416  1.00 26.73  ? 11  VAL B C   1 
ATOM   3538  O  O   . VAL B 1 11  ? 8.756   17.176  22.498  1.00 25.98  ? 11  VAL B O   1 
ATOM   3539  C  CB  . VAL B 1 11  ? 9.123   19.164  19.997  1.00 28.32  ? 11  VAL B CB  1 
ATOM   3540  C  CG1 . VAL B 1 11  ? 8.003   20.111  20.365  1.00 24.34  ? 11  VAL B CG1 1 
ATOM   3541  C  CG2 . VAL B 1 11  ? 10.008  19.761  18.902  1.00 22.95  ? 11  VAL B CG2 1 
ATOM   3542  N  N   . GLY B 1 12  ? 8.970   19.245  23.383  1.00 27.39  ? 12  GLY B N   1 
ATOM   3543  C  CA  . GLY B 1 12  ? 8.250   18.928  24.592  1.00 22.05  ? 12  GLY B CA  1 
ATOM   3544  C  C   . GLY B 1 12  ? 9.092   18.452  25.763  1.00 23.78  ? 12  GLY B C   1 
ATOM   3545  O  O   . GLY B 1 12  ? 8.537   18.233  26.841  1.00 23.96  ? 12  GLY B O   1 
ATOM   3546  N  N   . PHE B 1 13  ? 10.401  18.269  25.590  1.00 27.31  ? 13  PHE B N   1 
ATOM   3547  C  CA  . PHE B 1 13  ? 11.299  17.940  26.703  1.00 21.85  ? 13  PHE B CA  1 
ATOM   3548  C  C   . PHE B 1 13  ? 11.635  19.229  27.438  1.00 25.40  ? 13  PHE B C   1 
ATOM   3549  O  O   . PHE B 1 13  ? 12.420  20.059  26.946  1.00 25.73  ? 13  PHE B O   1 
ATOM   3550  C  CB  . PHE B 1 13  ? 12.557  17.264  26.183  1.00 20.76  ? 13  PHE B CB  1 
ATOM   3551  C  CG  . PHE B 1 13  ? 13.522  16.827  27.245  1.00 25.37  ? 13  PHE B CG  1 
ATOM   3552  C  CD1 . PHE B 1 13  ? 13.084  16.175  28.384  1.00 25.02  ? 13  PHE B CD1 1 
ATOM   3553  C  CD2 . PHE B 1 13  ? 14.892  17.049  27.079  1.00 23.13  ? 13  PHE B CD2 1 
ATOM   3554  C  CE1 . PHE B 1 13  ? 13.998  15.756  29.350  1.00 29.35  ? 13  PHE B CE1 1 
ATOM   3555  C  CE2 . PHE B 1 13  ? 15.794  16.649  28.012  1.00 25.13  ? 13  PHE B CE2 1 
ATOM   3556  C  CZ  . PHE B 1 13  ? 15.366  15.993  29.157  1.00 28.26  ? 13  PHE B CZ  1 
ATOM   3557  N  N   . ARG B 1 14  ? 11.054  19.389  28.619  1.00 25.77  ? 14  ARG B N   1 
ATOM   3558  C  CA  . ARG B 1 14  ? 11.063  20.663  29.323  1.00 28.97  ? 14  ARG B CA  1 
ATOM   3559  C  C   . ARG B 1 14  ? 10.739  20.404  30.782  1.00 29.22  ? 14  ARG B C   1 
ATOM   3560  O  O   . ARG B 1 14  ? 10.115  19.385  31.123  1.00 26.83  ? 14  ARG B O   1 
ATOM   3561  C  CB  . ARG B 1 14  ? 10.056  21.648  28.713  1.00 25.33  ? 14  ARG B CB  1 
ATOM   3562  C  CG  . ARG B 1 14  ? 8.596   21.253  28.908  1.00 27.03  ? 14  ARG B CG  1 
ATOM   3563  C  CD  . ARG B 1 14  ? 7.635   22.078  28.034  1.00 25.11  ? 14  ARG B CD  1 
ATOM   3564  N  NE  . ARG B 1 14  ? 7.645   23.485  28.401  1.00 37.32  ? 14  ARG B NE  1 
ATOM   3565  C  CZ  . ARG B 1 14  ? 8.292   24.434  27.734  1.00 42.61  ? 14  ARG B CZ  1 
ATOM   3566  N  NH1 . ARG B 1 14  ? 8.831   24.202  26.544  1.00 32.14  ? 14  ARG B NH1 1 
ATOM   3567  N  NH2 . ARG B 1 14  ? 8.389   25.650  28.266  1.00 48.51  ? 14  ARG B NH2 1 
ATOM   3568  N  N   . ASN B 1 15  ? 11.193  21.327  31.643  1.00 24.20  ? 15  ASN B N   1 
ATOM   3569  C  CA  . ASN B 1 15  ? 10.806  21.293  33.049  1.00 29.37  ? 15  ASN B CA  1 
ATOM   3570  C  C   . ASN B 1 15  ? 9.371   21.782  33.181  1.00 31.64  ? 15  ASN B C   1 
ATOM   3571  O  O   . ASN B 1 15  ? 8.880   22.541  32.346  1.00 32.02  ? 15  ASN B O   1 
ATOM   3572  C  CB  . ASN B 1 15  ? 11.722  22.159  33.921  1.00 23.12  ? 15  ASN B CB  1 
ATOM   3573  C  CG  . ASN B 1 15  ? 13.048  21.502  34.211  1.00 21.72  ? 15  ASN B CG  1 
ATOM   3574  O  OD1 . ASN B 1 15  ? 13.133  20.303  34.376  1.00 25.27  ? 15  ASN B OD1 1 
ATOM   3575  N  ND2 . ASN B 1 15  ? 14.100  22.299  34.272  1.00 33.36  ? 15  ASN B ND2 1 
ATOM   3576  N  N   . VAL B 1 16  ? 8.683   21.334  34.232  1.00 27.50  ? 16  VAL B N   1 
ATOM   3577  C  CA  . VAL B 1 16  ? 7.271   21.653  34.397  1.00 29.51  ? 16  VAL B CA  1 
ATOM   3578  C  C   . VAL B 1 16  ? 7.099   22.443  35.685  1.00 29.33  ? 16  VAL B C   1 
ATOM   3579  O  O   . VAL B 1 16  ? 7.561   22.018  36.743  1.00 27.79  ? 16  VAL B O   1 
ATOM   3580  C  CB  . VAL B 1 16  ? 6.407   20.380  34.385  1.00 33.64  ? 16  VAL B CB  1 
ATOM   3581  C  CG1 . VAL B 1 16  ? 4.996   20.663  34.904  1.00 32.02  ? 16  VAL B CG1 1 
ATOM   3582  C  CG2 . VAL B 1 16  ? 6.376   19.781  32.953  1.00 27.49  ? 16  VAL B CG2 1 
ATOM   3583  N  N   . ARG B 1 17  ? 6.427   23.581  35.596  1.00 24.68  ? 17  ARG B N   1 
ATOM   3584  C  CA  . ARG B 1 17  ? 6.202   24.421  36.755  1.00 37.16  ? 17  ARG B CA  1 
ATOM   3585  C  C   . ARG B 1 17  ? 4.723   24.426  37.119  1.00 44.29  ? 17  ARG B C   1 
ATOM   3586  O  O   . ARG B 1 17  ? 3.855   24.049  36.327  1.00 36.51  ? 17  ARG B O   1 
ATOM   3587  C  CB  . ARG B 1 17  ? 6.695   25.852  36.501  1.00 43.98  ? 17  ARG B CB  1 
ATOM   3588  C  CG  . ARG B 1 17  ? 8.094   25.907  35.880  1.00 43.56  ? 17  ARG B CG  1 
ATOM   3589  C  CD  . ARG B 1 17  ? 8.377   27.250  35.231  1.00 46.69  ? 17  ARG B CD  1 
ATOM   3590  N  NE  . ARG B 1 17  ? 9.781   27.629  35.344  1.00 51.78  ? 17  ARG B NE  1 
ATOM   3591  C  CZ  . ARG B 1 17  ? 10.379  27.977  36.475  1.00 52.17  ? 17  ARG B CZ  1 
ATOM   3592  N  NH1 . ARG B 1 17  ? 9.711   28.063  37.611  1.00 51.57  ? 17  ARG B NH1 1 
ATOM   3593  N  NH2 . ARG B 1 17  ? 11.683  28.237  36.467  1.00 54.72  ? 17  ARG B NH2 1 
ATOM   3594  N  N   . GLU B 1 18  ? 4.464   24.820  38.360  1.00 40.67  ? 18  GLU B N   1 
ATOM   3595  C  CA  . GLU B 1 18  ? 3.130   25.129  38.856  1.00 43.64  ? 18  GLU B CA  1 
ATOM   3596  C  C   . GLU B 1 18  ? 3.341   26.211  39.893  1.00 45.53  ? 18  GLU B C   1 
ATOM   3597  O  O   . GLU B 1 18  ? 4.122   26.009  40.829  1.00 42.66  ? 18  GLU B O   1 
ATOM   3598  C  CB  . GLU B 1 18  ? 2.442   23.909  39.481  1.00 45.28  ? 18  GLU B CB  1 
ATOM   3599  C  CG  . GLU B 1 18  ? 1.970   22.873  38.486  1.00 48.79  ? 18  GLU B CG  1 
ATOM   3600  C  CD  . GLU B 1 18  ? 1.598   21.574  39.143  1.00 50.88  ? 18  GLU B CD  1 
ATOM   3601  O  OE1 . GLU B 1 18  ? 1.064   21.614  40.273  1.00 51.95  ? 18  GLU B OE1 1 
ATOM   3602  O  OE2 . GLU B 1 18  ? 1.854   20.512  38.530  1.00 57.63  ? 18  GLU B OE2 1 
ATOM   3603  N  N   . GLY B 1 19  ? 2.695   27.351  39.699  1.00 45.68  ? 19  GLY B N   1 
ATOM   3604  C  CA  . GLY B 1 19  ? 2.917   28.489  40.566  1.00 47.57  ? 19  GLY B CA  1 
ATOM   3605  C  C   . GLY B 1 19  ? 4.384   28.767  40.825  1.00 48.04  ? 19  GLY B C   1 
ATOM   3606  O  O   . GLY B 1 19  ? 4.803   28.874  41.980  1.00 51.26  ? 19  GLY B O   1 
ATOM   3607  N  N   . GLY B 1 20  ? 5.185   28.832  39.762  1.00 54.02  ? 20  GLY B N   1 
ATOM   3608  C  CA  . GLY B 1 20  ? 6.555   29.297  39.853  1.00 51.96  ? 20  GLY B CA  1 
ATOM   3609  C  C   . GLY B 1 20  ? 7.601   28.281  40.277  1.00 57.40  ? 20  GLY B C   1 
ATOM   3610  O  O   . GLY B 1 20  ? 8.782   28.479  39.967  1.00 63.97  ? 20  GLY B O   1 
ATOM   3611  N  N   . GLU B 1 21  ? 7.228   27.216  40.993  1.00 51.41  ? 21  GLU B N   1 
ATOM   3612  C  CA  . GLU B 1 21  ? 8.180   26.211  41.466  1.00 51.05  ? 21  GLU B CA  1 
ATOM   3613  C  C   . GLU B 1 21  ? 8.169   25.003  40.528  1.00 46.82  ? 21  GLU B C   1 
ATOM   3614  O  O   . GLU B 1 21  ? 7.096   24.502  40.168  1.00 44.26  ? 21  GLU B O   1 
ATOM   3615  C  CB  . GLU B 1 21  ? 7.840   25.767  42.891  1.00 55.77  ? 21  GLU B CB  1 
ATOM   3616  C  CG  . GLU B 1 21  ? 7.328   26.861  43.825  1.00 56.84  ? 21  GLU B CG  1 
ATOM   3617  C  CD  . GLU B 1 21  ? 7.175   26.380  45.269  1.00 70.07  ? 21  GLU B CD  1 
ATOM   3618  O  OE1 . GLU B 1 21  ? 6.195   26.787  45.935  1.00 67.30  ? 21  GLU B OE1 1 
ATOM   3619  O  OE2 . GLU B 1 21  ? 8.032   25.598  45.746  1.00 76.01  ? 21  GLU B OE2 1 
ATOM   3620  N  N   . ILE B 1 22  ? 9.359   24.536  40.137  1.00 44.81  ? 22  ILE B N   1 
ATOM   3621  C  CA  . ILE B 1 22  ? 9.461   23.397  39.221  1.00 39.75  ? 22  ILE B CA  1 
ATOM   3622  C  C   . ILE B 1 22  ? 9.093   22.115  39.957  1.00 34.83  ? 22  ILE B C   1 
ATOM   3623  O  O   . ILE B 1 22  ? 9.778   21.700  40.898  1.00 32.60  ? 22  ILE B O   1 
ATOM   3624  C  CB  . ILE B 1 22  ? 10.866  23.272  38.623  1.00 32.88  ? 22  ILE B CB  1 
ATOM   3625  C  CG1 . ILE B 1 22  ? 11.170  24.400  37.641  1.00 36.14  ? 22  ILE B CG1 1 
ATOM   3626  C  CG2 . ILE B 1 22  ? 10.990  21.956  37.878  1.00 31.64  ? 22  ILE B CG2 1 
ATOM   3627  C  CD1 . ILE B 1 22  ? 12.633  24.419  37.237  1.00 34.27  ? 22  ILE B CD1 1 
ATOM   3628  N  N   . THR B 1 23  ? 8.049   21.448  39.485  1.00 33.20  ? 23  THR B N   1 
ATOM   3629  C  CA  . THR B 1 23  ? 7.569   20.211  40.086  1.00 34.54  ? 23  THR B CA  1 
ATOM   3630  C  C   . THR B 1 23  ? 8.203   18.964  39.474  1.00 32.49  ? 23  THR B C   1 
ATOM   3631  O  O   . THR B 1 23  ? 8.152   17.903  40.093  1.00 28.58  ? 23  THR B O   1 
ATOM   3632  C  CB  . THR B 1 23  ? 6.050   20.134  39.926  1.00 37.05  ? 23  THR B CB  1 
ATOM   3633  O  OG1 . THR B 1 23  ? 5.731   20.234  38.533  1.00 36.48  ? 23  THR B OG1 1 
ATOM   3634  C  CG2 . THR B 1 23  ? 5.389   21.297  40.638  1.00 39.48  ? 23  THR B CG2 1 
ATOM   3635  N  N   . GLY B 1 24  ? 8.788   19.068  38.282  1.00 33.39  ? 24  GLY B N   1 
ATOM   3636  C  CA  . GLY B 1 24  ? 9.297   17.901  37.580  1.00 27.05  ? 24  GLY B CA  1 
ATOM   3637  C  C   . GLY B 1 24  ? 9.625   18.251  36.137  1.00 29.59  ? 24  GLY B C   1 
ATOM   3638  O  O   . GLY B 1 24  ? 9.837   19.422  35.802  1.00 31.68  ? 24  GLY B O   1 
ATOM   3639  N  N   . PHE B 1 25  ? 9.656   17.226  35.286  1.00 27.78  ? 25  PHE B N   1 
ATOM   3640  C  CA  . PHE B 1 25  ? 9.866   17.456  33.866  1.00 23.28  ? 25  PHE B CA  1 
ATOM   3641  C  C   . PHE B 1 25  ? 9.041   16.480  33.040  1.00 28.09  ? 25  PHE B C   1 
ATOM   3642  O  O   . PHE B 1 25  ? 8.632   15.415  33.507  1.00 25.54  ? 25  PHE B O   1 
ATOM   3643  C  CB  . PHE B 1 25  ? 11.349  17.349  33.494  1.00 22.81  ? 25  PHE B CB  1 
ATOM   3644  C  CG  . PHE B 1 25  ? 11.867  15.964  33.521  1.00 23.83  ? 25  PHE B CG  1 
ATOM   3645  C  CD1 . PHE B 1 25  ? 12.219  15.370  34.727  1.00 26.28  ? 25  PHE B CD1 1 
ATOM   3646  C  CD2 . PHE B 1 25  ? 11.998  15.241  32.357  1.00 25.19  ? 25  PHE B CD2 1 
ATOM   3647  C  CE1 . PHE B 1 25  ? 12.701  14.085  34.762  1.00 30.21  ? 25  PHE B CE1 1 
ATOM   3648  C  CE2 . PHE B 1 25  ? 12.460  13.934  32.382  1.00 26.30  ? 25  PHE B CE2 1 
ATOM   3649  C  CZ  . PHE B 1 25  ? 12.816  13.355  33.592  1.00 34.63  ? 25  PHE B CZ  1 
ATOM   3650  N  N   . GLN B 1 26  ? 8.843   16.842  31.776  1.00 28.19  ? 26  GLN B N   1 
ATOM   3651  C  CA  . GLN B 1 26  ? 8.069   16.036  30.854  1.00 26.70  ? 26  GLN B CA  1 
ATOM   3652  C  C   . GLN B 1 26  ? 8.877   15.762  29.601  1.00 21.50  ? 26  GLN B C   1 
ATOM   3653  O  O   . GLN B 1 26  ? 9.898   16.407  29.325  1.00 26.41  ? 26  GLN B O   1 
ATOM   3654  C  CB  . GLN B 1 26  ? 6.746   16.715  30.487  1.00 29.76  ? 26  GLN B CB  1 
ATOM   3655  C  CG  . GLN B 1 26  ? 6.918   18.007  29.723  1.00 25.01  ? 26  GLN B CG  1 
ATOM   3656  C  CD  . GLN B 1 26  ? 5.636   18.487  29.127  1.00 27.86  ? 26  GLN B CD  1 
ATOM   3657  O  OE1 . GLN B 1 26  ? 4.605   18.489  29.787  1.00 30.12  ? 26  GLN B OE1 1 
ATOM   3658  N  NE2 . GLN B 1 26  ? 5.687   18.916  27.859  1.00 29.28  ? 26  GLN B NE2 1 
ATOM   3659  N  N   . PHE B 1 27  ? 8.434   14.757  28.862  1.00 25.97  ? 27  PHE B N   1 
ATOM   3660  C  CA  . PHE B 1 27  ? 8.894   14.542  27.495  1.00 21.17  ? 27  PHE B CA  1 
ATOM   3661  C  C   . PHE B 1 27  ? 7.742   13.931  26.741  1.00 22.82  ? 27  PHE B C   1 
ATOM   3662  O  O   . PHE B 1 27  ? 6.719   13.573  27.325  1.00 28.50  ? 27  PHE B O   1 
ATOM   3663  C  CB  . PHE B 1 27  ? 10.145  13.660  27.402  1.00 21.18  ? 27  PHE B CB  1 
ATOM   3664  C  CG  . PHE B 1 27  ? 10.007  12.314  28.040  1.00 24.36  ? 27  PHE B CG  1 
ATOM   3665  C  CD1 . PHE B 1 27  ? 10.142  12.172  29.411  1.00 26.12  ? 27  PHE B CD1 1 
ATOM   3666  C  CD2 . PHE B 1 27  ? 9.779   11.175  27.270  1.00 26.81  ? 27  PHE B CD2 1 
ATOM   3667  C  CE1 . PHE B 1 27  ? 10.024  10.915  30.011  1.00 22.14  ? 27  PHE B CE1 1 
ATOM   3668  C  CE2 . PHE B 1 27  ? 9.663   9.927   27.864  1.00 26.00  ? 27  PHE B CE2 1 
ATOM   3669  C  CZ  . PHE B 1 27  ? 9.791   9.801   29.235  1.00 26.42  ? 27  PHE B CZ  1 
ATOM   3670  N  N   . ARG B 1 28  ? 7.920   13.797  25.436  1.00 25.71  ? 28  ARG B N   1 
ATOM   3671  C  CA  . ARG B 1 28  ? 6.863   13.295  24.579  1.00 25.90  ? 28  ARG B CA  1 
ATOM   3672  C  C   . ARG B 1 28  ? 7.350   12.024  23.910  1.00 25.54  ? 28  ARG B C   1 
ATOM   3673  O  O   . ARG B 1 28  ? 8.540   11.880  23.646  1.00 22.87  ? 28  ARG B O   1 
ATOM   3674  C  CB  . ARG B 1 28  ? 6.470   14.346  23.527  1.00 26.10  ? 28  ARG B CB  1 
ATOM   3675  C  CG  . ARG B 1 28  ? 5.477   15.326  24.072  1.00 30.09  ? 28  ARG B CG  1 
ATOM   3676  C  CD  . ARG B 1 28  ? 5.448   16.588  23.261  1.00 28.33  ? 28  ARG B CD  1 
ATOM   3677  N  NE  . ARG B 1 28  ? 4.675   16.387  22.051  1.00 27.55  ? 28  ARG B NE  1 
ATOM   3678  C  CZ  . ARG B 1 28  ? 5.215   16.217  20.853  1.00 27.56  ? 28  ARG B CZ  1 
ATOM   3679  N  NH1 . ARG B 1 28  ? 6.525   16.297  20.668  1.00 22.38  ? 28  ARG B NH1 1 
ATOM   3680  N  NH2 . ARG B 1 28  ? 4.421   15.954  19.820  1.00 27.11  ? 28  ARG B NH2 1 
ATOM   3681  N  N   . VAL B 1 29  ? 6.418   11.112  23.628  1.00 24.92  ? 29  VAL B N   1 
ATOM   3682  C  CA  . VAL B 1 29  ? 6.740   9.780   23.141  1.00 23.69  ? 29  VAL B CA  1 
ATOM   3683  C  C   . VAL B 1 29  ? 5.782   9.452   22.018  1.00 25.36  ? 29  VAL B C   1 
ATOM   3684  O  O   . VAL B 1 29  ? 4.563   9.533   22.195  1.00 30.09  ? 29  VAL B O   1 
ATOM   3685  C  CB  . VAL B 1 29  ? 6.625   8.707   24.237  1.00 24.49  ? 29  VAL B CB  1 
ATOM   3686  C  CG1 . VAL B 1 29  ? 7.013   7.334   23.664  1.00 23.82  ? 29  VAL B CG1 1 
ATOM   3687  C  CG2 . VAL B 1 29  ? 7.515   9.054   25.392  1.00 25.53  ? 29  VAL B CG2 1 
ATOM   3688  N  N   . ARG B 1 30  ? 6.330   9.065   20.880  1.00 25.27  ? 30  ARG B N   1 
ATOM   3689  C  CA  . ARG B 1 30  ? 5.538   8.576   19.763  1.00 27.23  ? 30  ARG B CA  1 
ATOM   3690  C  C   . ARG B 1 30  ? 5.136   7.121   20.006  1.00 22.24  ? 30  ARG B C   1 
ATOM   3691  O  O   . ARG B 1 30  ? 5.983   6.270   20.274  1.00 23.36  ? 30  ARG B O   1 
ATOM   3692  C  CB  . ARG B 1 30  ? 6.341   8.716   18.463  1.00 24.59  ? 30  ARG B CB  1 
ATOM   3693  C  CG  . ARG B 1 30  ? 5.739   8.005   17.273  1.00 29.82  ? 30  ARG B CG  1 
ATOM   3694  C  CD  . ARG B 1 30  ? 6.445   8.349   15.918  1.00 24.53  ? 30  ARG B CD  1 
ATOM   3695  N  NE  . ARG B 1 30  ? 7.693   7.604   15.776  1.00 26.63  ? 30  ARG B NE  1 
ATOM   3696  C  CZ  . ARG B 1 30  ? 7.775   6.305   15.516  1.00 28.30  ? 30  ARG B CZ  1 
ATOM   3697  N  NH1 . ARG B 1 30  ? 6.697   5.584   15.252  1.00 27.11  ? 30  ARG B NH1 1 
ATOM   3698  N  NH2 . ARG B 1 30  ? 8.966   5.712   15.547  1.00 26.54  ? 30  ARG B NH2 1 
ATOM   3699  N  N   . MET B 1 31  ? 3.847   6.839   19.919  1.00 23.82  ? 31  MET B N   1 
ATOM   3700  C  CA  . MET B 1 31  ? 3.366   5.468   20.031  1.00 25.93  ? 31  MET B CA  1 
ATOM   3701  C  C   . MET B 1 31  ? 4.112   4.567   19.049  1.00 21.95  ? 31  MET B C   1 
ATOM   3702  O  O   . MET B 1 31  ? 4.074   4.828   17.840  1.00 25.30  ? 31  MET B O   1 
ATOM   3703  C  CB  . MET B 1 31  ? 1.867   5.429   19.749  1.00 23.38  ? 31  MET B CB  1 
ATOM   3704  C  CG  . MET B 1 31  ? 1.323   4.048   19.389  1.00 23.61  ? 31  MET B CG  1 
ATOM   3705  S  SD  . MET B 1 31  ? 1.509   2.933   20.780  1.00 24.67  ? 31  MET B SD  1 
ATOM   3706  C  CE  . MET B 1 31  ? -0.090  3.195   21.502  1.00 22.99  ? 31  MET B CE  1 
ATOM   3707  N  N   . PRO B 1 32  ? 4.805   3.516   19.522  1.00 23.98  ? 32  PRO B N   1 
ATOM   3708  C  CA  . PRO B 1 32  ? 5.564   2.645   18.596  1.00 25.17  ? 32  PRO B CA  1 
ATOM   3709  C  C   . PRO B 1 32  ? 4.738   1.577   17.920  1.00 25.69  ? 32  PRO B C   1 
ATOM   3710  O  O   . PRO B 1 32  ? 5.175   1.032   16.890  1.00 26.31  ? 32  PRO B O   1 
ATOM   3711  C  CB  . PRO B 1 32  ? 6.601   1.988   19.508  1.00 26.35  ? 32  PRO B CB  1 
ATOM   3712  C  CG  . PRO B 1 32  ? 5.872   1.879   20.830  1.00 23.89  ? 32  PRO B CG  1 
ATOM   3713  C  CD  . PRO B 1 32  ? 5.040   3.154   20.932  1.00 23.40  ? 32  PRO B CD  1 
ATOM   3714  N  N   . SER B 1 33  ? 3.590   1.230   18.481  1.00 22.57  ? 33  SER B N   1 
ATOM   3715  C  CA  . SER B 1 33  ? 2.745   0.208   17.896  1.00 25.67  ? 33  SER B CA  1 
ATOM   3716  C  C   . SER B 1 33  ? 2.168   0.705   16.573  1.00 23.90  ? 33  SER B C   1 
ATOM   3717  O  O   . SER B 1 33  ? 2.223   1.885   16.241  1.00 26.69  ? 33  SER B O   1 
ATOM   3718  C  CB  . SER B 1 33  ? 1.636   -0.166  18.871  1.00 20.44  ? 33  SER B CB  1 
ATOM   3719  O  OG  . SER B 1 33  ? 0.835   -1.157  18.327  1.00 31.80  ? 33  SER B OG  1 
ATOM   3720  N  N   . TYR B 1 34  ? 1.626   -0.214  15.791  1.00 34.98  ? 34  TYR B N   1 
ATOM   3721  C  CA  . TYR B 1 34  ? 1.069   0.228   14.525  1.00 27.31  ? 34  TYR B CA  1 
ATOM   3722  C  C   . TYR B 1 34  ? -0.314  0.842   14.670  1.00 27.54  ? 34  TYR B C   1 
ATOM   3723  O  O   . TYR B 1 34  ? -0.868  1.284   13.665  1.00 27.61  ? 34  TYR B O   1 
ATOM   3724  C  CB  . TYR B 1 34  ? 1.037   -0.915  13.512  1.00 32.55  ? 34  TYR B CB  1 
ATOM   3725  C  CG  . TYR B 1 34  ? 0.784   -2.268  14.087  1.00 36.03  ? 34  TYR B CG  1 
ATOM   3726  C  CD1 . TYR B 1 34  ? -0.478  -2.619  14.536  1.00 32.76  ? 34  TYR B CD1 1 
ATOM   3727  C  CD2 . TYR B 1 34  ? 1.806   -3.212  14.169  1.00 37.76  ? 34  TYR B CD2 1 
ATOM   3728  C  CE1 . TYR B 1 34  ? -0.720  -3.859  15.070  1.00 35.34  ? 34  TYR B CE1 1 
ATOM   3729  C  CE2 . TYR B 1 34  ? 1.566   -4.465  14.698  1.00 38.65  ? 34  TYR B CE2 1 
ATOM   3730  C  CZ  . TYR B 1 34  ? 0.299   -4.779  15.141  1.00 40.90  ? 34  TYR B CZ  1 
ATOM   3731  O  OH  . TYR B 1 34  ? 0.032   -6.021  15.660  1.00 55.50  ? 34  TYR B OH  1 
ATOM   3732  N  N   . ARG B 1 35  ? -0.854  0.951   15.888  1.00 26.54  ? 35  ARG B N   1 
ATOM   3733  C  CA  . ARG B 1 35  ? -2.170  1.534   16.092  1.00 17.09  ? 35  ARG B CA  1 
ATOM   3734  C  C   . ARG B 1 35  ? -2.151  2.387   17.352  1.00 20.51  ? 35  ARG B C   1 
ATOM   3735  O  O   . ARG B 1 35  ? -1.302  2.216   18.225  1.00 22.86  ? 35  ARG B O   1 
ATOM   3736  C  CB  . ARG B 1 35  ? -3.247  0.437   16.206  1.00 19.78  ? 35  ARG B CB  1 
ATOM   3737  C  CG  . ARG B 1 35  ? -2.924  -0.596  17.293  1.00 23.88  ? 35  ARG B CG  1 
ATOM   3738  C  CD  . ARG B 1 35  ? -4.155  -1.329  17.711  1.00 25.10  ? 35  ARG B CD  1 
ATOM   3739  N  NE  . ARG B 1 35  ? -3.879  -2.357  18.702  1.00 27.99  ? 35  ARG B NE  1 
ATOM   3740  C  CZ  . ARG B 1 35  ? -4.774  -2.824  19.566  1.00 29.63  ? 35  ARG B CZ  1 
ATOM   3741  N  NH1 . ARG B 1 35  ? -6.008  -2.347  19.610  1.00 25.81  ? 35  ARG B NH1 1 
ATOM   3742  N  NH2 . ARG B 1 35  ? -4.427  -3.809  20.392  1.00 24.37  ? 35  ARG B NH2 1 
ATOM   3743  N  N   . GLY B 1 36  ? -3.091  3.317   17.445  1.00 19.38  ? 36  GLY B N   1 
ATOM   3744  C  CA  . GLY B 1 36  ? -3.440  3.844   18.742  1.00 22.40  ? 36  GLY B CA  1 
ATOM   3745  C  C   . GLY B 1 36  ? -4.171  2.775   19.531  1.00 24.19  ? 36  GLY B C   1 
ATOM   3746  O  O   . GLY B 1 36  ? -4.631  1.794   18.969  1.00 26.37  ? 36  GLY B O   1 
ATOM   3747  N  N   . MET B 1 37  ? -4.264  2.953   20.844  1.00 19.11  ? 37  MET B N   1 
ATOM   3748  C  CA  . MET B 1 37  ? -4.736  1.890   21.726  1.00 24.61  ? 37  MET B CA  1 
ATOM   3749  C  C   . MET B 1 37  ? -5.493  2.485   22.894  1.00 21.87  ? 37  MET B C   1 
ATOM   3750  O  O   . MET B 1 37  ? -5.224  3.615   23.311  1.00 25.96  ? 37  MET B O   1 
ATOM   3751  C  CB  . MET B 1 37  ? -3.555  1.078   22.260  1.00 24.38  ? 37  MET B CB  1 
ATOM   3752  C  CG  . MET B 1 37  ? -2.791  0.369   21.155  1.00 30.74  ? 37  MET B CG  1 
ATOM   3753  S  SD  . MET B 1 37  ? -1.338  -0.466  21.755  1.00 36.93  ? 37  MET B SD  1 
ATOM   3754  C  CE  . MET B 1 37  ? -1.669  -0.336  23.477  1.00 20.53  ? 37  MET B CE  1 
ATOM   3755  N  N   . ALA B 1 38  ? -6.409  1.697   23.454  1.00 23.69  ? 38  ALA B N   1 
ATOM   3756  C  CA  . ALA B 1 38  ? -7.023  2.085   24.711  1.00 23.59  ? 38  ALA B CA  1 
ATOM   3757  C  C   . ALA B 1 38  ? -5.935  2.313   25.754  1.00 21.47  ? 38  ALA B C   1 
ATOM   3758  O  O   . ALA B 1 38  ? -4.973  1.549   25.849  1.00 22.33  ? 38  ALA B O   1 
ATOM   3759  C  CB  . ALA B 1 38  ? -8.010  1.002   25.170  1.00 22.27  ? 38  ALA B CB  1 
ATOM   3760  N  N   . ALA B 1 39  ? -6.072  3.385   26.530  1.00 25.64  ? 39  ALA B N   1 
ATOM   3761  C  CA  . ALA B 1 39  ? -5.034  3.723   27.503  1.00 22.34  ? 39  ALA B CA  1 
ATOM   3762  C  C   . ALA B 1 39  ? -4.859  2.670   28.600  1.00 24.35  ? 39  ALA B C   1 
ATOM   3763  O  O   . ALA B 1 39  ? -3.771  2.567   29.166  1.00 20.99  ? 39  ALA B O   1 
ATOM   3764  C  CB  . ALA B 1 39  ? -5.322  5.091   28.121  1.00 25.26  ? 39  ALA B CB  1 
ATOM   3765  N  N   . SER B 1 40  ? -5.869  1.856   28.897  1.00 21.97  ? 40  SER B N   1 
ATOM   3766  C  CA  . SER B 1 40  ? -5.634  0.849   29.925  1.00 20.35  ? 40  SER B CA  1 
ATOM   3767  C  C   . SER B 1 40  ? -4.660  -0.246  29.508  1.00 24.34  ? 40  SER B C   1 
ATOM   3768  O  O   . SER B 1 40  ? -4.209  -0.995  30.380  1.00 27.18  ? 40  SER B O   1 
ATOM   3769  C  CB  . SER B 1 40  ? -6.950  0.226   30.350  1.00 23.74  ? 40  SER B CB  1 
ATOM   3770  O  OG  . SER B 1 40  ? -7.710  -0.118  29.218  1.00 24.15  ? 40  SER B OG  1 
ATOM   3771  N  N   . LEU B 1 41  ? -4.321  -0.364  28.220  1.00 20.35  ? 41  LEU B N   1 
ATOM   3772  C  CA  . LEU B 1 41  ? -3.361  -1.356  27.733  1.00 24.74  ? 41  LEU B CA  1 
ATOM   3773  C  C   . LEU B 1 41  ? -1.909  -0.929  27.903  1.00 22.86  ? 41  LEU B C   1 
ATOM   3774  O  O   . LEU B 1 41  ? -1.001  -1.700  27.554  1.00 24.31  ? 41  LEU B O   1 
ATOM   3775  C  CB  . LEU B 1 41  ? -3.613  -1.651  26.253  1.00 22.77  ? 41  LEU B CB  1 
ATOM   3776  C  CG  . LEU B 1 41  ? -5.042  -2.113  25.974  1.00 26.33  ? 41  LEU B CG  1 
ATOM   3777  C  CD1 . LEU B 1 41  ? -5.380  -2.092  24.454  1.00 21.94  ? 41  LEU B CD1 1 
ATOM   3778  C  CD2 . LEU B 1 41  ? -5.196  -3.470  26.579  1.00 28.64  ? 41  LEU B CD2 1 
ATOM   3779  N  N   . ILE B 1 42  ? -1.678  0.288   28.378  1.00 25.82  ? 42  ILE B N   1 
ATOM   3780  C  CA  . ILE B 1 42  ? -0.338  0.721   28.763  1.00 26.55  ? 42  ILE B CA  1 
ATOM   3781  C  C   . ILE B 1 42  ? 0.053   0.023   30.054  1.00 26.58  ? 42  ILE B C   1 
ATOM   3782  O  O   . ILE B 1 42  ? -0.735  -0.033  31.006  1.00 27.67  ? 42  ILE B O   1 
ATOM   3783  C  CB  . ILE B 1 42  ? -0.304  2.248   28.934  1.00 26.77  ? 42  ILE B CB  1 
ATOM   3784  C  CG1 . ILE B 1 42  ? -0.523  2.946   27.585  1.00 20.59  ? 42  ILE B CG1 1 
ATOM   3785  C  CG2 . ILE B 1 42  ? 0.987   2.688   29.602  1.00 29.70  ? 42  ILE B CG2 1 
ATOM   3786  C  CD1 . ILE B 1 42  ? -1.305  4.230   27.697  1.00 23.43  ? 42  ILE B CD1 1 
ATOM   3787  N  N   . ASP B 1 43  ? 1.266   -0.514  30.099  1.00 28.05  ? 43  ASP B N   1 
ATOM   3788  C  CA  . ASP B 1 43  ? 1.778   -1.103  31.327  1.00 28.35  ? 43  ASP B CA  1 
ATOM   3789  C  C   . ASP B 1 43  ? 2.883   -0.258  31.956  1.00 30.41  ? 43  ASP B C   1 
ATOM   3790  O  O   . ASP B 1 43  ? 3.571   -0.732  32.861  1.00 32.34  ? 43  ASP B O   1 
ATOM   3791  C  CB  . ASP B 1 43  ? 2.285   -2.519  31.065  1.00 26.74  ? 43  ASP B CB  1 
ATOM   3792  C  CG  . ASP B 1 43  ? 1.418   -3.585  31.706  1.00 33.15  ? 43  ASP B CG  1 
ATOM   3793  O  OD1 . ASP B 1 43  ? 0.258   -3.296  32.105  1.00 31.92  ? 43  ASP B OD1 1 
ATOM   3794  O  OD2 . ASP B 1 43  ? 1.924   -4.719  31.828  1.00 31.68  ? 43  ASP B OD2 1 
ATOM   3795  N  N   . GLY B 1 44  ? 3.074   0.972   31.507  1.00 31.84  ? 44  GLY B N   1 
ATOM   3796  C  CA  . GLY B 1 44  ? 3.950   1.907   32.186  1.00 25.60  ? 44  GLY B CA  1 
ATOM   3797  C  C   . GLY B 1 44  ? 5.160   2.269   31.344  1.00 28.00  ? 44  GLY B C   1 
ATOM   3798  O  O   . GLY B 1 44  ? 5.387   1.737   30.260  1.00 29.60  ? 44  GLY B O   1 
ATOM   3799  N  N   . ILE B 1 45  ? 5.958   3.187   31.881  1.00 23.47  ? 45  ILE B N   1 
ATOM   3800  C  CA  . ILE B 1 45  ? 7.178   3.610   31.216  1.00 26.08  ? 45  ILE B CA  1 
ATOM   3801  C  C   . ILE B 1 45  ? 8.239   3.869   32.282  1.00 24.50  ? 45  ILE B C   1 
ATOM   3802  O  O   . ILE B 1 45  ? 8.066   4.733   33.148  1.00 28.27  ? 45  ILE B O   1 
ATOM   3803  C  CB  . ILE B 1 45  ? 6.939   4.855   30.331  1.00 24.38  ? 45  ILE B CB  1 
ATOM   3804  C  CG1 . ILE B 1 45  ? 8.230   5.348   29.724  1.00 23.90  ? 45  ILE B CG1 1 
ATOM   3805  C  CG2 . ILE B 1 45  ? 6.297   5.960   31.103  1.00 22.74  ? 45  ILE B CG2 1 
ATOM   3806  C  CD1 . ILE B 1 45  ? 8.020   6.374   28.587  1.00 24.08  ? 45  ILE B CD1 1 
ATOM   3807  N  N   . GLY B 1 46  ? 9.307   3.089   32.265  1.00 26.88  ? 46  GLY B N   1 
ATOM   3808  C  CA  . GLY B 1 46  ? 10.451  3.412   33.100  1.00 31.00  ? 46  GLY B CA  1 
ATOM   3809  C  C   . GLY B 1 46  ? 11.283  4.511   32.458  1.00 32.33  ? 46  GLY B C   1 
ATOM   3810  O  O   . GLY B 1 46  ? 11.366  4.619   31.239  1.00 30.62  ? 46  GLY B O   1 
ATOM   3811  N  N   . VAL B 1 47  ? 11.885  5.358   33.291  1.00 31.31  ? 47  VAL B N   1 
ATOM   3812  C  CA  . VAL B 1 47  ? 12.612  6.528   32.819  1.00 31.61  ? 47  VAL B CA  1 
ATOM   3813  C  C   . VAL B 1 47  ? 13.938  6.621   33.562  1.00 35.02  ? 47  VAL B C   1 
ATOM   3814  O  O   . VAL B 1 47  ? 14.005  6.373   34.772  1.00 40.08  ? 47  VAL B O   1 
ATOM   3815  C  CB  . VAL B 1 47  ? 11.784  7.818   33.002  1.00 30.26  ? 47  VAL B CB  1 
ATOM   3816  C  CG1 . VAL B 1 47  ? 12.555  9.011   32.482  1.00 29.31  ? 47  VAL B CG1 1 
ATOM   3817  C  CG2 . VAL B 1 47  ? 10.456  7.719   32.256  1.00 27.19  ? 47  VAL B CG2 1 
ATOM   3818  N  N   . ARG B 1 48  ? 14.994  6.982   32.838  1.00 38.92  ? 48  ARG B N   1 
ATOM   3819  C  CA  . ARG B 1 48  ? 16.304  7.140   33.451  1.00 38.80  ? 48  ARG B CA  1 
ATOM   3820  C  C   . ARG B 1 48  ? 17.119  8.194   32.715  1.00 33.32  ? 48  ARG B C   1 
ATOM   3821  O  O   . ARG B 1 48  ? 17.151  8.214   31.483  1.00 38.06  ? 48  ARG B O   1 
ATOM   3822  C  CB  . ARG B 1 48  ? 17.083  5.822   33.464  1.00 34.77  ? 48  ARG B CB  1 
ATOM   3823  C  CG  . ARG B 1 48  ? 18.404  5.945   34.176  1.00 40.05  ? 48  ARG B CG  1 
ATOM   3824  C  CD  . ARG B 1 48  ? 19.109  4.615   34.359  1.00 49.68  ? 48  ARG B CD  1 
ATOM   3825  N  NE  . ARG B 1 48  ? 20.558  4.778   34.288  1.00 57.27  ? 48  ARG B NE  1 
ATOM   3826  C  CZ  . ARG B 1 48  ? 21.335  5.073   35.323  1.00 54.69  ? 48  ARG B CZ  1 
ATOM   3827  N  NH1 . ARG B 1 48  ? 20.834  5.237   36.541  1.00 50.45  ? 48  ARG B NH1 1 
ATOM   3828  N  NH2 . ARG B 1 48  ? 22.645  5.208   35.132  1.00 53.01  ? 48  ARG B NH2 1 
ATOM   3829  N  N   . ILE B 1 49  ? 17.782  9.061   33.484  1.00 32.82  ? 49  ILE B N   1 
ATOM   3830  C  CA  . ILE B 1 49  ? 18.922  9.836   33.015  1.00 31.75  ? 49  ILE B CA  1 
ATOM   3831  C  C   . ILE B 1 49  ? 20.032  9.588   34.031  1.00 35.79  ? 49  ILE B C   1 
ATOM   3832  O  O   . ILE B 1 49  ? 19.876  9.934   35.207  1.00 38.42  ? 49  ILE B O   1 
ATOM   3833  C  CB  . ILE B 1 49  ? 18.631  11.343  32.903  1.00 31.08  ? 49  ILE B CB  1 
ATOM   3834  C  CG1 . ILE B 1 49  ? 17.353  11.591  32.096  1.00 27.83  ? 49  ILE B CG1 1 
ATOM   3835  C  CG2 . ILE B 1 49  ? 19.797  12.057  32.278  1.00 32.56  ? 49  ILE B CG2 1 
ATOM   3836  C  CD1 . ILE B 1 49  ? 16.738  12.946  32.305  1.00 32.31  ? 49  ILE B CD1 1 
ATOM   3837  N  N   . PRO B 1 50  ? 21.148  8.970   33.645  1.00 39.56  ? 50  PRO B N   1 
ATOM   3838  C  CA  . PRO B 1 50  ? 22.213  8.649   34.613  1.00 39.44  ? 50  PRO B CA  1 
ATOM   3839  C  C   . PRO B 1 50  ? 22.601  9.828   35.495  1.00 41.27  ? 50  PRO B C   1 
ATOM   3840  O  O   . PRO B 1 50  ? 22.913  10.922  35.007  1.00 39.45  ? 50  PRO B O   1 
ATOM   3841  C  CB  . PRO B 1 50  ? 23.385  8.223   33.720  1.00 35.63  ? 50  PRO B CB  1 
ATOM   3842  C  CG  . PRO B 1 50  ? 23.049  8.739   32.345  1.00 46.33  ? 50  PRO B CG  1 
ATOM   3843  C  CD  . PRO B 1 50  ? 21.546  8.641   32.270  1.00 41.56  ? 50  PRO B CD  1 
ATOM   3844  N  N   . GLY B 1 51  ? 22.574  9.593   36.809  1.00 36.71  ? 51  GLY B N   1 
ATOM   3845  C  CA  . GLY B 1 51  ? 22.929  10.590  37.783  1.00 36.31  ? 51  GLY B CA  1 
ATOM   3846  C  C   . GLY B 1 51  ? 21.840  11.582  38.105  1.00 43.73  ? 51  GLY B C   1 
ATOM   3847  O  O   . GLY B 1 51  ? 22.032  12.412  39.002  1.00 38.75  ? 51  GLY B O   1 
ATOM   3848  N  N   . LEU B 1 52  ? 20.700  11.527  37.416  1.00 40.95  ? 52  LEU B N   1 
ATOM   3849  C  CA  . LEU B 1 52  ? 19.637  12.472  37.743  1.00 37.78  ? 52  LEU B CA  1 
ATOM   3850  C  C   . LEU B 1 52  ? 18.314  11.801  38.073  1.00 43.59  ? 52  LEU B C   1 
ATOM   3851  O  O   . LEU B 1 52  ? 17.650  12.204  39.037  1.00 38.13  ? 52  LEU B O   1 
ATOM   3852  C  CB  . LEU B 1 52  ? 19.453  13.456  36.576  1.00 40.08  ? 52  LEU B CB  1 
ATOM   3853  C  CG  . LEU B 1 52  ? 20.577  14.497  36.431  1.00 41.20  ? 52  LEU B CG  1 
ATOM   3854  C  CD1 . LEU B 1 52  ? 20.502  15.266  35.098  1.00 32.52  ? 52  LEU B CD1 1 
ATOM   3855  C  CD2 . LEU B 1 52  ? 20.576  15.463  37.616  1.00 42.02  ? 52  LEU B CD2 1 
ATOM   3856  N  N   . VAL B 1 53  ? 17.902  10.798  37.299  1.00 34.75  ? 53  VAL B N   1 
ATOM   3857  C  CA  . VAL B 1 53  ? 16.601  10.167  37.484  1.00 39.07  ? 53  VAL B CA  1 
ATOM   3858  C  C   . VAL B 1 53  ? 16.741  8.685   37.200  1.00 32.70  ? 53  VAL B C   1 
ATOM   3859  O  O   . VAL B 1 53  ? 17.499  8.280   36.315  1.00 33.49  ? 53  VAL B O   1 
ATOM   3860  C  CB  . VAL B 1 53  ? 15.507  10.777  36.572  1.00 39.04  ? 53  VAL B CB  1 
ATOM   3861  C  CG1 . VAL B 1 53  ? 14.170  10.096  36.824  1.00 36.32  ? 53  VAL B CG1 1 
ATOM   3862  C  CG2 . VAL B 1 53  ? 15.361  12.272  36.808  1.00 38.99  ? 53  VAL B CG2 1 
ATOM   3863  N  N   . ASP B 1 54  ? 16.007  7.881   37.959  1.00 39.14  ? 54  ASP B N   1 
ATOM   3864  C  CA  . ASP B 1 54  ? 15.890  6.450   37.697  1.00 38.04  ? 54  ASP B CA  1 
ATOM   3865  C  C   . ASP B 1 54  ? 14.595  6.017   38.377  1.00 39.71  ? 54  ASP B C   1 
ATOM   3866  O  O   . ASP B 1 54  ? 14.577  5.805   39.594  1.00 40.31  ? 54  ASP B O   1 
ATOM   3867  C  CB  . ASP B 1 54  ? 17.087  5.681   38.228  1.00 43.57  ? 54  ASP B CB  1 
ATOM   3868  C  CG  . ASP B 1 54  ? 17.169  4.272   37.669  1.00 42.77  ? 54  ASP B CG  1 
ATOM   3869  O  OD1 . ASP B 1 54  ? 16.119  3.724   37.264  1.00 39.21  ? 54  ASP B OD1 1 
ATOM   3870  O  OD2 . ASP B 1 54  ? 18.282  3.714   37.640  1.00 41.55  ? 54  ASP B OD2 1 
ATOM   3871  N  N   . VAL B 1 55  ? 13.518  5.932   37.601  1.00 35.60  ? 55  VAL B N   1 
ATOM   3872  C  CA  . VAL B 1 55  ? 12.215  5.624   38.171  1.00 33.92  ? 55  VAL B CA  1 
ATOM   3873  C  C   . VAL B 1 55  ? 11.630  4.423   37.454  1.00 31.12  ? 55  VAL B C   1 
ATOM   3874  O  O   . VAL B 1 55  ? 11.901  4.176   36.273  1.00 34.72  ? 55  VAL B O   1 
ATOM   3875  C  CB  . VAL B 1 55  ? 11.244  6.826   38.106  1.00 36.25  ? 55  VAL B CB  1 
ATOM   3876  C  CG1 . VAL B 1 55  ? 11.675  7.901   39.092  1.00 32.37  ? 55  VAL B CG1 1 
ATOM   3877  C  CG2 . VAL B 1 55  ? 11.153  7.370   36.697  1.00 34.96  ? 55  VAL B CG2 1 
ATOM   3878  N  N   . GLY B 1 56  ? 10.829  3.676   38.186  1.00 35.08  ? 56  GLY B N   1 
ATOM   3879  C  CA  . GLY B 1 56  ? 10.177  2.514   37.654  1.00 38.48  ? 56  GLY B CA  1 
ATOM   3880  C  C   . GLY B 1 56  ? 8.955   2.887   36.856  1.00 34.98  ? 56  GLY B C   1 
ATOM   3881  O  O   . GLY B 1 56  ? 8.455   4.020   36.897  1.00 36.73  ? 56  GLY B O   1 
ATOM   3882  N  N   . PRO B 1 57  ? 8.449   1.914   36.103  1.00 37.86  ? 57  PRO B N   1 
ATOM   3883  C  CA  . PRO B 1 57  ? 7.398   2.223   35.120  1.00 37.97  ? 57  PRO B CA  1 
ATOM   3884  C  C   . PRO B 1 57  ? 6.081   2.694   35.730  1.00 34.89  ? 57  PRO B C   1 
ATOM   3885  O  O   . PRO B 1 57  ? 5.284   3.326   35.024  1.00 35.35  ? 57  PRO B O   1 
ATOM   3886  C  CB  . PRO B 1 57  ? 7.237   0.902   34.350  1.00 31.05  ? 57  PRO B CB  1 
ATOM   3887  C  CG  . PRO B 1 57  ? 7.911   -0.139  35.184  1.00 38.60  ? 57  PRO B CG  1 
ATOM   3888  C  CD  . PRO B 1 57  ? 8.994   0.557   35.933  1.00 37.20  ? 57  PRO B CD  1 
ATOM   3889  N  N   . ASP B 1 58  ? 5.830   2.441   37.004  1.00 29.44  ? 58  ASP B N   1 
ATOM   3890  C  CA  . ASP B 1 58  ? 4.582   2.868   37.612  1.00 32.27  ? 58  ASP B CA  1 
ATOM   3891  C  C   . ASP B 1 58  ? 4.646   4.290   38.161  1.00 28.11  ? 58  ASP B C   1 
ATOM   3892  O  O   . ASP B 1 58  ? 3.649   4.767   38.709  1.00 31.52  ? 58  ASP B O   1 
ATOM   3893  C  CB  . ASP B 1 58  ? 4.185   1.904   38.734  1.00 40.46  ? 58  ASP B CB  1 
ATOM   3894  C  CG  . ASP B 1 58  ? 5.231   1.837   39.834  1.00 46.69  ? 58  ASP B CG  1 
ATOM   3895  O  OD1 . ASP B 1 58  ? 6.325   1.268   39.602  1.00 50.58  ? 58  ASP B OD1 1 
ATOM   3896  O  OD2 . ASP B 1 58  ? 4.970   2.406   40.916  1.00 48.20  ? 58  ASP B OD2 1 
ATOM   3897  N  N   . VAL B 1 59  ? 5.774   4.982   38.011  1.00 28.89  ? 59  VAL B N   1 
ATOM   3898  C  CA  . VAL B 1 59  ? 5.954   6.313   38.599  1.00 31.14  ? 59  VAL B CA  1 
ATOM   3899  C  C   . VAL B 1 59  ? 5.565   7.444   37.648  1.00 28.51  ? 59  VAL B C   1 
ATOM   3900  O  O   . VAL B 1 59  ? 4.932   8.408   38.096  1.00 22.68  ? 59  VAL B O   1 
ATOM   3901  C  CB  . VAL B 1 59  ? 7.398   6.503   39.094  1.00 32.12  ? 59  VAL B CB  1 
ATOM   3902  C  CG1 . VAL B 1 59  ? 7.565   7.869   39.783  1.00 30.64  ? 59  VAL B CG1 1 
ATOM   3903  C  CG2 . VAL B 1 59  ? 7.770   5.362   40.056  1.00 37.16  ? 59  VAL B CG2 1 
ATOM   3904  N  N   . PRO B 1 60  ? 5.931   7.428   36.364  1.00 27.34  ? 60  PRO B N   1 
ATOM   3905  C  CA  . PRO B 1 60  ? 5.580   8.584   35.519  1.00 22.88  ? 60  PRO B CA  1 
ATOM   3906  C  C   . PRO B 1 60  ? 4.077   8.761   35.383  1.00 21.07  ? 60  PRO B C   1 
ATOM   3907  O  O   . PRO B 1 60  ? 3.307   7.806   35.482  1.00 26.67  ? 60  PRO B O   1 
ATOM   3908  C  CB  . PRO B 1 60  ? 6.241   8.255   34.177  1.00 26.24  ? 60  PRO B CB  1 
ATOM   3909  C  CG  . PRO B 1 60  ? 7.442   7.472   34.565  1.00 28.81  ? 60  PRO B CG  1 
ATOM   3910  C  CD  . PRO B 1 60  ? 6.913   6.567   35.683  1.00 23.83  ? 60  PRO B CD  1 
ATOM   3911  N  N   . LEU B 1 61  ? 3.655   10.011  35.212  1.00 25.89  ? 61  LEU B N   1 
ATOM   3912  C  CA  . LEU B 1 61  ? 2.261   10.344  34.950  1.00 25.04  ? 61  LEU B CA  1 
ATOM   3913  C  C   . LEU B 1 61  ? 2.048   10.562  33.460  1.00 25.92  ? 61  LEU B C   1 
ATOM   3914  O  O   . LEU B 1 61  ? 2.950   11.035  32.753  1.00 24.04  ? 61  LEU B O   1 
ATOM   3915  C  CB  . LEU B 1 61  ? 1.832   11.601  35.704  1.00 23.24  ? 61  LEU B CB  1 
ATOM   3916  C  CG  . LEU B 1 61  ? 2.017   11.631  37.218  1.00 26.34  ? 61  LEU B CG  1 
ATOM   3917  C  CD1 . LEU B 1 61  ? 1.215   12.776  37.757  1.00 31.85  ? 61  LEU B CD1 1 
ATOM   3918  C  CD2 . LEU B 1 61  ? 1.522   10.328  37.834  1.00 30.34  ? 61  LEU B CD2 1 
ATOM   3919  N  N   . TRP B 1 62  ? 0.832   10.259  32.991  1.00 23.77  ? 62  TRP B N   1 
ATOM   3920  C  CA  . TRP B 1 62  ? 0.518   10.256  31.557  1.00 24.80  ? 62  TRP B CA  1 
ATOM   3921  C  C   . TRP B 1 62  ? -0.576  11.262  31.241  1.00 22.24  ? 62  TRP B C   1 
ATOM   3922  O  O   . TRP B 1 62  ? -1.690  11.152  31.774  1.00 22.76  ? 62  TRP B O   1 
ATOM   3923  C  CB  . TRP B 1 62  ? 0.044   8.880   31.085  1.00 24.49  ? 62  TRP B CB  1 
ATOM   3924  C  CG  . TRP B 1 62  ? 1.051   7.825   31.084  1.00 20.12  ? 62  TRP B CG  1 
ATOM   3925  C  CD1 . TRP B 1 62  ? 1.688   7.298   32.161  1.00 25.81  ? 62  TRP B CD1 1 
ATOM   3926  C  CD2 . TRP B 1 62  ? 1.540   7.136   29.943  1.00 20.32  ? 62  TRP B CD2 1 
ATOM   3927  N  NE1 . TRP B 1 62  ? 2.558   6.309   31.756  1.00 22.61  ? 62  TRP B NE1 1 
ATOM   3928  C  CE2 . TRP B 1 62  ? 2.493   6.209   30.390  1.00 24.32  ? 62  TRP B CE2 1 
ATOM   3929  C  CE3 . TRP B 1 62  ? 1.275   7.224   28.572  1.00 22.74  ? 62  TRP B CE3 1 
ATOM   3930  C  CZ2 . TRP B 1 62  ? 3.171   5.357   29.518  1.00 20.62  ? 62  TRP B CZ2 1 
ATOM   3931  C  CZ3 . TRP B 1 62  ? 1.962   6.397   27.708  1.00 25.01  ? 62  TRP B CZ3 1 
ATOM   3932  C  CH2 . TRP B 1 62  ? 2.887   5.463   28.188  1.00 23.44  ? 62  TRP B CH2 1 
ATOM   3933  N  N   . THR B 1 63  ? -0.290  12.188  30.315  1.00 24.10  ? 63  THR B N   1 
ATOM   3934  C  CA  . THR B 1 63  ? -1.311  13.076  29.770  1.00 23.30  ? 63  THR B CA  1 
ATOM   3935  C  C   . THR B 1 63  ? -1.734  12.559  28.394  1.00 22.08  ? 63  THR B C   1 
ATOM   3936  O  O   . THR B 1 63  ? -0.898  12.373  27.504  1.00 28.58  ? 63  THR B O   1 
ATOM   3937  C  CB  . THR B 1 63  ? -0.824  14.522  29.712  1.00 20.47  ? 63  THR B CB  1 
ATOM   3938  O  OG1 . THR B 1 63  ? -0.608  14.991  31.047  1.00 26.92  ? 63  THR B OG1 1 
ATOM   3939  C  CG2 . THR B 1 63  ? -1.871  15.425  29.045  1.00 21.26  ? 63  THR B CG2 1 
ATOM   3940  N  N   . LEU B 1 64  ? -3.033  12.294  28.244  1.00 25.06  ? 64  LEU B N   1 
ATOM   3941  C  CA  . LEU B 1 64  ? -3.606  11.663  27.066  1.00 25.96  ? 64  LEU B CA  1 
ATOM   3942  C  C   . LEU B 1 64  ? -5.002  12.224  26.889  1.00 27.14  ? 64  LEU B C   1 
ATOM   3943  O  O   . LEU B 1 64  ? -5.776  12.241  27.851  1.00 24.07  ? 64  LEU B O   1 
ATOM   3944  C  CB  . LEU B 1 64  ? -3.672  10.138  27.222  1.00 23.07  ? 64  LEU B CB  1 
ATOM   3945  C  CG  . LEU B 1 64  ? -2.359  9.400   27.456  1.00 23.90  ? 64  LEU B CG  1 
ATOM   3946  C  CD1 . LEU B 1 64  ? -2.573  8.113   28.242  1.00 29.87  ? 64  LEU B CD1 1 
ATOM   3947  C  CD2 . LEU B 1 64  ? -1.642  9.143   26.123  1.00 24.36  ? 64  LEU B CD2 1 
ATOM   3948  N  N   . GLN B 1 65  ? -5.312  12.688  25.673  1.00 21.30  ? 65  GLN B N   1 
ATOM   3949  C  CA  . GLN B 1 65  ? -6.615  13.276  25.366  1.00 22.71  ? 65  GLN B CA  1 
ATOM   3950  C  C   . GLN B 1 65  ? -6.989  14.345  26.397  1.00 27.21  ? 65  GLN B C   1 
ATOM   3951  O  O   . GLN B 1 65  ? -8.128  14.427  26.872  1.00 24.90  ? 65  GLN B O   1 
ATOM   3952  C  CB  . GLN B 1 65  ? -7.691  12.194  25.268  1.00 24.24  ? 65  GLN B CB  1 
ATOM   3953  C  CG  . GLN B 1 65  ? -7.363  11.098  24.219  1.00 24.58  ? 65  GLN B CG  1 
ATOM   3954  C  CD  . GLN B 1 65  ? -8.479  10.090  24.047  1.00 26.41  ? 65  GLN B CD  1 
ATOM   3955  O  OE1 . GLN B 1 65  ? -8.940  9.500   25.017  1.00 23.35  ? 65  GLN B OE1 1 
ATOM   3956  N  NE2 . GLN B 1 65  ? -8.896  9.861   22.800  1.00 24.56  ? 65  GLN B NE2 1 
ATOM   3957  N  N   . GLY B 1 66  ? -6.006  15.142  26.774  1.00 24.29  ? 66  GLY B N   1 
ATOM   3958  C  CA  . GLY B 1 66  ? -6.244  16.334  27.563  1.00 26.81  ? 66  GLY B CA  1 
ATOM   3959  C  C   . GLY B 1 66  ? -6.174  16.153  29.060  1.00 26.98  ? 66  GLY B C   1 
ATOM   3960  O  O   . GLY B 1 66  ? -6.292  17.140  29.790  1.00 33.17  ? 66  GLY B O   1 
ATOM   3961  N  N   . GLN B 1 67  ? -5.991  14.939  29.553  1.00 25.08  ? 67  GLN B N   1 
ATOM   3962  C  CA  . GLN B 1 67  ? -6.074  14.702  30.985  1.00 28.10  ? 67  GLN B CA  1 
ATOM   3963  C  C   . GLN B 1 67  ? -4.856  13.922  31.451  1.00 24.69  ? 67  GLN B C   1 
ATOM   3964  O  O   . GLN B 1 67  ? -4.293  13.124  30.695  1.00 23.27  ? 67  GLN B O   1 
ATOM   3965  C  CB  . GLN B 1 67  ? -7.353  13.940  31.326  1.00 29.38  ? 67  GLN B CB  1 
ATOM   3966  C  CG  . GLN B 1 67  ? -8.543  14.826  31.639  1.00 35.61  ? 67  GLN B CG  1 
ATOM   3967  C  CD  . GLN B 1 67  ? -9.645  14.056  32.356  1.00 35.04  ? 67  GLN B CD  1 
ATOM   3968  O  OE1 . GLN B 1 67  ? -9.533  13.770  33.542  1.00 38.41  ? 67  GLN B OE1 1 
ATOM   3969  N  NE2 . GLN B 1 67  ? -10.709 13.717  31.635  1.00 36.59  ? 67  GLN B NE2 1 
ATOM   3970  N  N   . GLN B 1 68  ? -4.456  14.139  32.706  1.00 20.37  ? 68  GLN B N   1 
ATOM   3971  C  CA  . GLN B 1 68  ? -3.278  13.485  33.264  1.00 21.84  ? 68  GLN B CA  1 
ATOM   3972  C  C   . GLN B 1 68  ? -3.686  12.378  34.240  1.00 22.86  ? 68  GLN B C   1 
ATOM   3973  O  O   . GLN B 1 68  ? -4.492  12.614  35.137  1.00 24.87  ? 68  GLN B O   1 
ATOM   3974  C  CB  . GLN B 1 68  ? -2.378  14.493  33.959  1.00 22.64  ? 68  GLN B CB  1 
ATOM   3975  C  CG  . GLN B 1 68  ? -1.069  13.877  34.451  1.00 25.89  ? 68  GLN B CG  1 
ATOM   3976  C  CD  . GLN B 1 68  ? -0.166  14.921  35.055  1.00 26.08  ? 68  GLN B CD  1 
ATOM   3977  O  OE1 . GLN B 1 68  ? -0.503  15.516  36.070  1.00 26.78  ? 68  GLN B OE1 1 
ATOM   3978  N  NE2 . GLN B 1 68  ? 0.966   15.175  34.418  1.00 25.05  ? 68  GLN B NE2 1 
ATOM   3979  N  N   . TYR B 1 69  ? -3.088  11.192  34.078  1.00 19.71  ? 69  TYR B N   1 
ATOM   3980  C  CA  . TYR B 1 69  ? -3.408  9.978   34.814  1.00 22.96  ? 69  TYR B CA  1 
ATOM   3981  C  C   . TYR B 1 69  ? -2.154  9.375   35.436  1.00 22.63  ? 69  TYR B C   1 
ATOM   3982  O  O   . TYR B 1 69  ? -1.047  9.506   34.897  1.00 23.45  ? 69  TYR B O   1 
ATOM   3983  C  CB  . TYR B 1 69  ? -4.055  8.921   33.881  1.00 25.39  ? 69  TYR B CB  1 
ATOM   3984  C  CG  . TYR B 1 69  ? -5.273  9.443   33.158  1.00 26.25  ? 69  TYR B CG  1 
ATOM   3985  C  CD1 . TYR B 1 69  ? -6.536  9.347   33.730  1.00 24.44  ? 69  TYR B CD1 1 
ATOM   3986  C  CD2 . TYR B 1 69  ? -5.156  10.068  31.909  1.00 22.09  ? 69  TYR B CD2 1 
ATOM   3987  C  CE1 . TYR B 1 69  ? -7.659  9.868   33.076  1.00 26.92  ? 69  TYR B CE1 1 
ATOM   3988  C  CE2 . TYR B 1 69  ? -6.268  10.571  31.252  1.00 22.57  ? 69  TYR B CE2 1 
ATOM   3989  C  CZ  . TYR B 1 69  ? -7.511  10.470  31.836  1.00 23.66  ? 69  TYR B CZ  1 
ATOM   3990  O  OH  . TYR B 1 69  ? -8.615  10.984  31.189  1.00 25.58  ? 69  TYR B OH  1 
ATOM   3991  N  N   . THR B 1 70  ? -2.330  8.703   36.578  1.00 24.23  ? 70  THR B N   1 
ATOM   3992  C  CA  . THR B 1 70  ? -1.313  7.746   36.996  1.00 25.13  ? 70  THR B CA  1 
ATOM   3993  C  C   . THR B 1 70  ? -1.495  6.434   36.224  1.00 23.57  ? 70  THR B C   1 
ATOM   3994  O  O   . THR B 1 70  ? -2.560  6.159   35.672  1.00 24.52  ? 70  THR B O   1 
ATOM   3995  C  CB  . THR B 1 70  ? -1.380  7.472   38.498  1.00 26.43  ? 70  THR B CB  1 
ATOM   3996  O  OG1 . THR B 1 70  ? -2.616  6.814   38.820  1.00 29.21  ? 70  THR B OG1 1 
ATOM   3997  C  CG2 . THR B 1 70  ? -1.294  8.760   39.287  1.00 28.66  ? 70  THR B CG2 1 
ATOM   3998  N  N   . LEU B 1 71  ? -0.443  5.615   36.201  1.00 23.03  ? 71  LEU B N   1 
ATOM   3999  C  CA  . LEU B 1 71  ? -0.580  4.275   35.631  1.00 27.25  ? 71  LEU B CA  1 
ATOM   4000  C  C   . LEU B 1 71  ? -1.788  3.538   36.215  1.00 27.83  ? 71  LEU B C   1 
ATOM   4001  O  O   . LEU B 1 71  ? -2.602  2.972   35.478  1.00 21.79  ? 71  LEU B O   1 
ATOM   4002  C  CB  . LEU B 1 71  ? 0.694   3.465   35.862  1.00 26.50  ? 71  LEU B CB  1 
ATOM   4003  C  CG  . LEU B 1 71  ? 0.711   2.037   35.285  1.00 24.29  ? 71  LEU B CG  1 
ATOM   4004  C  CD1 . LEU B 1 71  ? 0.260   1.982   33.835  1.00 24.75  ? 71  LEU B CD1 1 
ATOM   4005  C  CD2 . LEU B 1 71  ? 2.086   1.460   35.427  1.00 22.04  ? 71  LEU B CD2 1 
ATOM   4006  N  N   . ALA B 1 72  ? -1.935  3.558   37.544  1.00 28.27  ? 72  ALA B N   1 
ATOM   4007  C  CA  . ALA B 1 72  ? -3.001  2.780   38.174  1.00 25.26  ? 72  ALA B CA  1 
ATOM   4008  C  C   . ALA B 1 72  ? -4.366  3.279   37.742  1.00 25.56  ? 72  ALA B C   1 
ATOM   4009  O  O   . ALA B 1 72  ? -5.324  2.499   37.667  1.00 30.42  ? 72  ALA B O   1 
ATOM   4010  C  CB  . ALA B 1 72  ? -2.875  2.819   39.698  1.00 27.30  ? 72  ALA B CB  1 
ATOM   4011  N  N   . GLU B 1 73  ? -4.472  4.568   37.439  1.00 23.39  ? 73  GLU B N   1 
ATOM   4012  C  CA  . GLU B 1 73  ? -5.714  5.086   36.883  1.00 22.75  ? 73  GLU B CA  1 
ATOM   4013  C  C   . GLU B 1 73  ? -5.904  4.619   35.450  1.00 23.39  ? 73  GLU B C   1 
ATOM   4014  O  O   . GLU B 1 73  ? -7.011  4.230   35.068  1.00 29.51  ? 73  GLU B O   1 
ATOM   4015  C  CB  . GLU B 1 73  ? -5.729  6.599   36.950  1.00 21.23  ? 73  GLU B CB  1 
ATOM   4016  C  CG  . GLU B 1 73  ? -6.059  7.137   38.328  1.00 24.08  ? 73  GLU B CG  1 
ATOM   4017  C  CD  . GLU B 1 73  ? -5.706  8.596   38.474  1.00 28.53  ? 73  GLU B CD  1 
ATOM   4018  O  OE1 . GLU B 1 73  ? -4.964  9.114   37.589  1.00 27.47  ? 73  GLU B OE1 1 
ATOM   4019  O  OE2 . GLU B 1 73  ? -6.171  9.218   39.461  1.00 28.11  ? 73  GLU B OE2 1 
ATOM   4020  N  N   . LEU B 1 74  ? -4.844  4.657   34.643  1.00 24.54  ? 74  LEU B N   1 
ATOM   4021  C  CA  . LEU B 1 74  ? -4.945  4.157   33.272  1.00 21.23  ? 74  LEU B CA  1 
ATOM   4022  C  C   . LEU B 1 74  ? -5.467  2.727   33.257  1.00 24.53  ? 74  LEU B C   1 
ATOM   4023  O  O   . LEU B 1 74  ? -6.364  2.407   32.485  1.00 23.18  ? 74  LEU B O   1 
ATOM   4024  C  CB  . LEU B 1 74  ? -3.594  4.244   32.573  1.00 25.97  ? 74  LEU B CB  1 
ATOM   4025  C  CG  . LEU B 1 74  ? -3.035  5.642   32.231  1.00 22.14  ? 74  LEU B CG  1 
ATOM   4026  C  CD1 . LEU B 1 74  ? -1.779  5.498   31.418  1.00 23.77  ? 74  LEU B CD1 1 
ATOM   4027  C  CD2 . LEU B 1 74  ? -4.029  6.459   31.480  1.00 19.07  ? 74  LEU B CD2 1 
ATOM   4028  N  N   . TRP B 1 75  ? -4.964  1.875   34.161  1.00 24.71  ? 75  TRP B N   1 
ATOM   4029  C  CA  . TRP B 1 75  ? -5.414  0.487   34.225  1.00 26.68  ? 75  TRP B CA  1 
ATOM   4030  C  C   . TRP B 1 75  ? -6.912  0.371   34.484  1.00 27.33  ? 75  TRP B C   1 
ATOM   4031  O  O   . TRP B 1 75  ? -7.548  -0.561  33.980  1.00 32.87  ? 75  TRP B O   1 
ATOM   4032  C  CB  . TRP B 1 75  ? -4.639  -0.271  35.311  1.00 26.22  ? 75  TRP B CB  1 
ATOM   4033  C  CG  . TRP B 1 75  ? -3.252  -0.634  34.872  1.00 24.27  ? 75  TRP B CG  1 
ATOM   4034  C  CD1 . TRP B 1 75  ? -2.798  -0.712  33.591  1.00 27.06  ? 75  TRP B CD1 1 
ATOM   4035  C  CD2 . TRP B 1 75  ? -2.145  -0.976  35.713  1.00 26.50  ? 75  TRP B CD2 1 
ATOM   4036  N  NE1 . TRP B 1 75  ? -1.475  -1.072  33.576  1.00 30.40  ? 75  TRP B NE1 1 
ATOM   4037  C  CE2 . TRP B 1 75  ? -1.053  -1.246  34.873  1.00 28.98  ? 75  TRP B CE2 1 
ATOM   4038  C  CE3 . TRP B 1 75  ? -1.974  -1.090  37.099  1.00 30.99  ? 75  TRP B CE3 1 
ATOM   4039  C  CZ2 . TRP B 1 75  ? 0.203   -1.615  35.373  1.00 32.00  ? 75  TRP B CZ2 1 
ATOM   4040  C  CZ3 . TRP B 1 75  ? -0.725  -1.454  37.595  1.00 27.67  ? 75  TRP B CZ3 1 
ATOM   4041  C  CH2 . TRP B 1 75  ? 0.343   -1.712  36.735  1.00 29.06  ? 75  TRP B CH2 1 
ATOM   4042  N  N   . ASP B 1 76  ? -7.494  1.297   35.253  1.00 26.54  ? 76  ASP B N   1 
ATOM   4043  C  CA  . ASP B 1 76  ? -8.890  1.210   35.675  1.00 31.54  ? 76  ASP B CA  1 
ATOM   4044  C  C   . ASP B 1 76  ? -9.841  1.999   34.779  1.00 30.66  ? 76  ASP B C   1 
ATOM   4045  O  O   . ASP B 1 76  ? -11.060 1.803   34.869  1.00 24.31  ? 76  ASP B O   1 
ATOM   4046  C  CB  . ASP B 1 76  ? -9.052  1.712   37.128  1.00 30.49  ? 76  ASP B CB  1 
ATOM   4047  C  CG  . ASP B 1 76  ? -8.452  0.762   38.174  1.00 41.58  ? 76  ASP B CG  1 
ATOM   4048  O  OD1 . ASP B 1 76  ? -8.345  -0.455  37.917  1.00 40.16  ? 76  ASP B OD1 1 
ATOM   4049  O  OD2 . ASP B 1 76  ? -8.092  1.245   39.278  1.00 50.02  ? 76  ASP B OD2 1 
ATOM   4050  N  N   . GLY B 1 77  ? -9.323  2.884   33.913  1.00 28.87  ? 77  GLY B N   1 
ATOM   4051  C  CA  . GLY B 1 77  ? -10.190 3.750   33.136  1.00 26.53  ? 77  GLY B CA  1 
ATOM   4052  C  C   . GLY B 1 77  ? -10.794 3.066   31.917  1.00 31.18  ? 77  GLY B C   1 
ATOM   4053  O  O   . GLY B 1 77  ? -10.329 2.026   31.462  1.00 30.82  ? 77  GLY B O   1 
ATOM   4054  N  N   . ASP B 1 78  ? -11.872 3.657   31.386  1.00 26.95  ? 78  ASP B N   1 
ATOM   4055  C  CA  . ASP B 1 78  ? -12.447 3.201   30.129  1.00 29.70  ? 78  ASP B CA  1 
ATOM   4056  C  C   . ASP B 1 78  ? -12.629 4.389   29.205  1.00 28.56  ? 78  ASP B C   1 
ATOM   4057  O  O   . ASP B 1 78  ? -12.966 5.487   29.653  1.00 26.56  ? 78  ASP B O   1 
ATOM   4058  C  CB  . ASP B 1 78  ? -13.801 2.494   30.323  1.00 32.92  ? 78  ASP B CB  1 
ATOM   4059  C  CG  . ASP B 1 78  ? -13.639 1.063   30.757  1.00 35.72  ? 78  ASP B CG  1 
ATOM   4060  O  OD1 . ASP B 1 78  ? -13.473 0.187   29.875  1.00 39.80  ? 78  ASP B OD1 1 
ATOM   4061  O  OD2 . ASP B 1 78  ? -13.667 0.817   31.983  1.00 45.72  ? 78  ASP B OD2 1 
ATOM   4062  N  N   . GLY B 1 79  ? -12.408 4.159   27.912  1.00 24.51  ? 79  GLY B N   1 
ATOM   4063  C  CA  . GLY B 1 79  ? -12.635 5.176   26.911  1.00 30.79  ? 79  GLY B CA  1 
ATOM   4064  C  C   . GLY B 1 79  ? -11.473 6.120   26.659  1.00 30.97  ? 79  GLY B C   1 
ATOM   4065  O  O   . GLY B 1 79  ? -11.500 6.847   25.661  1.00 29.25  ? 79  GLY B O   1 
ATOM   4066  N  N   . VAL B 1 80  ? -10.468 6.139   27.524  1.00 25.44  ? 80  VAL B N   1 
ATOM   4067  C  CA  . VAL B 1 80  ? -9.261  6.922   27.281  1.00 27.24  ? 80  VAL B CA  1 
ATOM   4068  C  C   . VAL B 1 80  ? -8.332  6.159   26.348  1.00 26.32  ? 80  VAL B C   1 
ATOM   4069  O  O   . VAL B 1 80  ? -8.187  4.935   26.442  1.00 24.57  ? 80  VAL B O   1 
ATOM   4070  C  CB  . VAL B 1 80  ? -8.562  7.262   28.608  1.00 26.82  ? 80  VAL B CB  1 
ATOM   4071  C  CG1 . VAL B 1 80  ? -7.332  8.154   28.368  1.00 24.65  ? 80  VAL B CG1 1 
ATOM   4072  C  CG2 . VAL B 1 80  ? -9.540  7.942   29.554  1.00 28.37  ? 80  VAL B CG2 1 
ATOM   4073  N  N   . ARG B 1 81  ? -7.666  6.888   25.460  1.00 24.78  ? 81  ARG B N   1 
ATOM   4074  C  CA  . ARG B 1 81  ? -6.844  6.256   24.441  1.00 25.59  ? 81  ARG B CA  1 
ATOM   4075  C  C   . ARG B 1 81  ? -5.494  6.959   24.320  1.00 23.91  ? 81  ARG B C   1 
ATOM   4076  O  O   . ARG B 1 81  ? -5.331  8.128   24.682  1.00 24.35  ? 81  ARG B O   1 
ATOM   4077  C  CB  . ARG B 1 81  ? -7.584  6.245   23.099  1.00 23.73  ? 81  ARG B CB  1 
ATOM   4078  C  CG  . ARG B 1 81  ? -8.858  5.437   23.181  1.00 27.48  ? 81  ARG B CG  1 
ATOM   4079  C  CD  . ARG B 1 81  ? -9.367  4.994   21.830  1.00 31.12  ? 81  ARG B CD  1 
ATOM   4080  N  NE  . ARG B 1 81  ? -8.432  4.152   21.087  1.00 31.99  ? 81  ARG B NE  1 
ATOM   4081  C  CZ  . ARG B 1 81  ? -7.863  4.580   19.978  1.00 25.04  ? 81  ARG B CZ  1 
ATOM   4082  N  NH1 . ARG B 1 81  ? -8.036  5.810   19.572  1.00 30.08  ? 81  ARG B NH1 1 
ATOM   4083  N  NH2 . ARG B 1 81  ? -7.112  3.755   19.262  1.00 29.80  ? 81  ARG B NH2 1 
ATOM   4084  N  N   . TRP B 1 82  ? -4.514  6.205   23.833  1.00 24.69  ? 82  TRP B N   1 
ATOM   4085  C  CA  . TRP B 1 82  ? -3.298  6.773   23.267  1.00 23.25  ? 82  TRP B CA  1 
ATOM   4086  C  C   . TRP B 1 82  ? -3.471  6.797   21.754  1.00 21.94  ? 82  TRP B C   1 
ATOM   4087  O  O   . TRP B 1 82  ? -3.174  5.808   21.073  1.00 22.85  ? 82  TRP B O   1 
ATOM   4088  C  CB  . TRP B 1 82  ? -2.068  5.958   23.659  1.00 23.09  ? 82  TRP B CB  1 
ATOM   4089  C  CG  . TRP B 1 82  ? -0.782  6.577   23.258  1.00 23.25  ? 82  TRP B CG  1 
ATOM   4090  C  CD1 . TRP B 1 82  ? -0.610  7.703   22.514  1.00 18.73  ? 82  TRP B CD1 1 
ATOM   4091  C  CD2 . TRP B 1 82  ? 0.532   6.090   23.553  1.00 20.75  ? 82  TRP B CD2 1 
ATOM   4092  N  NE1 . TRP B 1 82  ? 0.720   7.950   22.346  1.00 17.43  ? 82  TRP B NE1 1 
ATOM   4093  C  CE2 . TRP B 1 82  ? 1.442   6.969   22.960  1.00 18.16  ? 82  TRP B CE2 1 
ATOM   4094  C  CE3 . TRP B 1 82  ? 1.021   4.996   24.262  1.00 23.05  ? 82  TRP B CE3 1 
ATOM   4095  C  CZ2 . TRP B 1 82  ? 2.820   6.807   23.069  1.00 23.11  ? 82  TRP B CZ2 1 
ATOM   4096  C  CZ3 . TRP B 1 82  ? 2.394   4.823   24.349  1.00 16.64  ? 82  TRP B CZ3 1 
ATOM   4097  C  CH2 . TRP B 1 82  ? 3.275   5.726   23.760  1.00 22.20  ? 82  TRP B CH2 1 
ATOM   4098  N  N   . PRO B 1 83  ? -3.960  7.897   21.199  1.00 24.30  ? 83  PRO B N   1 
ATOM   4099  C  CA  . PRO B 1 83  ? -4.162  7.963   19.748  1.00 20.19  ? 83  PRO B CA  1 
ATOM   4100  C  C   . PRO B 1 83  ? -2.845  8.002   19.000  1.00 21.42  ? 83  PRO B C   1 
ATOM   4101  O  O   . PRO B 1 83  ? -1.893  8.671   19.409  1.00 24.10  ? 83  PRO B O   1 
ATOM   4102  C  CB  . PRO B 1 83  ? -4.947  9.265   19.554  1.00 27.06  ? 83  PRO B CB  1 
ATOM   4103  C  CG  . PRO B 1 83  ? -5.395  9.672   20.987  1.00 21.26  ? 83  PRO B CG  1 
ATOM   4104  C  CD  . PRO B 1 83  ? -4.364  9.132   21.872  1.00 21.62  ? 83  PRO B CD  1 
ATOM   4105  N  N   . LEU B 1 84  ? -2.824  7.310   17.855  1.00 24.37  ? 84  LEU B N   1 
ATOM   4106  C  CA  . LEU B 1 84  ? -1.623  7.211   17.052  1.00 20.97  ? 84  LEU B CA  1 
ATOM   4107  C  C   . LEU B 1 84  ? -1.101  8.581   16.660  1.00 21.64  ? 84  LEU B C   1 
ATOM   4108  O  O   . LEU B 1 84  ? 0.114   8.764   16.538  1.00 25.10  ? 84  LEU B O   1 
ATOM   4109  C  CB  . LEU B 1 84  ? -1.903  6.384   15.789  1.00 18.88  ? 84  LEU B CB  1 
ATOM   4110  C  CG  . LEU B 1 84  ? -0.695  6.164   14.883  1.00 20.54  ? 84  LEU B CG  1 
ATOM   4111  C  CD1 . LEU B 1 84  ? 0.484   5.504   15.604  1.00 18.59  ? 84  LEU B CD1 1 
ATOM   4112  C  CD2 . LEU B 1 84  ? -1.104  5.358   13.662  1.00 22.14  ? 84  LEU B CD2 1 
ATOM   4113  N  N   . GLU B 1 85  ? -1.995  9.552   16.496  1.00 25.16  ? 85  GLU B N   1 
ATOM   4114  C  CA  . GLU B 1 85  ? -1.639  10.894  16.055  1.00 26.36  ? 85  GLU B CA  1 
ATOM   4115  C  C   . GLU B 1 85  ? -1.128  11.785  17.185  1.00 25.01  ? 85  GLU B C   1 
ATOM   4116  O  O   . GLU B 1 85  ? -0.661  12.896  16.911  1.00 28.98  ? 85  GLU B O   1 
ATOM   4117  C  CB  . GLU B 1 85  ? -2.853  11.553  15.373  1.00 21.74  ? 85  GLU B CB  1 
ATOM   4118  C  CG  . GLU B 1 85  ? -4.029  11.866  16.290  1.00 27.13  ? 85  GLU B CG  1 
ATOM   4119  C  CD  . GLU B 1 85  ? -5.110  10.750  16.361  1.00 30.23  ? 85  GLU B CD  1 
ATOM   4120  O  OE1 . GLU B 1 85  ? -4.810  9.541   16.165  1.00 23.76  ? 85  GLU B OE1 1 
ATOM   4121  O  OE2 . GLU B 1 85  ? -6.280  11.092  16.645  1.00 25.68  ? 85  GLU B OE2 1 
ATOM   4122  N  N   . ASP B 1 86  ? -1.175  11.338  18.434  1.00 23.47  ? 86  ASP B N   1 
ATOM   4123  C  CA  . ASP B 1 86  ? -0.726  12.151  19.566  1.00 21.46  ? 86  ASP B CA  1 
ATOM   4124  C  C   . ASP B 1 86  ? 0.466   11.496  20.223  1.00 24.23  ? 86  ASP B C   1 
ATOM   4125  O  O   . ASP B 1 86  ? 0.374   10.345  20.668  1.00 21.27  ? 86  ASP B O   1 
ATOM   4126  C  CB  . ASP B 1 86  ? -1.779  12.310  20.654  1.00 22.44  ? 86  ASP B CB  1 
ATOM   4127  C  CG  . ASP B 1 86  ? -3.027  12.955  20.165  1.00 27.93  ? 86  ASP B CG  1 
ATOM   4128  O  OD1 . ASP B 1 86  ? -2.955  13.739  19.199  1.00 31.57  ? 86  ASP B OD1 1 
ATOM   4129  O  OD2 . ASP B 1 86  ? -4.080  12.702  20.787  1.00 29.84  ? 86  ASP B OD2 1 
ATOM   4130  N  N   . ALA B 1 87  ? 1.555   12.244  20.359  1.00 21.40  ? 87  ALA B N   1 
ATOM   4131  C  CA  . ALA B 1 87  ? 2.594   11.762  21.242  1.00 22.30  ? 87  ALA B CA  1 
ATOM   4132  C  C   . ALA B 1 87  ? 2.017   11.691  22.652  1.00 24.53  ? 87  ALA B C   1 
ATOM   4133  O  O   . ALA B 1 87  ? 1.181   12.516  23.050  1.00 24.41  ? 87  ALA B O   1 
ATOM   4134  C  CB  . ALA B 1 87  ? 3.828   12.672  21.175  1.00 26.28  ? 87  ALA B CB  1 
ATOM   4135  N  N   . ALA B 1 88  ? 2.401   10.662  23.388  1.00 24.21  ? 88  ALA B N   1 
ATOM   4136  C  CA  . ALA B 1 88  ? 2.075   10.649  24.802  1.00 22.60  ? 88  ALA B CA  1 
ATOM   4137  C  C   . ALA B 1 88  ? 2.945   11.667  25.525  1.00 21.73  ? 88  ALA B C   1 
ATOM   4138  O  O   . ALA B 1 88  ? 4.122   11.824  25.206  1.00 29.99  ? 88  ALA B O   1 
ATOM   4139  C  CB  . ALA B 1 88  ? 2.284   9.250   25.380  1.00 22.87  ? 88  ALA B CB  1 
ATOM   4140  N  N   . ILE B 1 89  ? 2.373   12.370  26.493  1.00 22.24  ? 89  ILE B N   1 
ATOM   4141  C  CA  . ILE B 1 89  ? 3.133   13.312  27.306  1.00 27.41  ? 89  ILE B CA  1 
ATOM   4142  C  C   . ILE B 1 89  ? 3.417   12.633  28.642  1.00 24.51  ? 89  ILE B C   1 
ATOM   4143  O  O   . ILE B 1 89  ? 2.493   12.304  29.389  1.00 26.56  ? 89  ILE B O   1 
ATOM   4144  C  CB  . ILE B 1 89  ? 2.386   14.645  27.487  1.00 24.01  ? 89  ILE B CB  1 
ATOM   4145  C  CG1 . ILE B 1 89  ? 2.078   15.291  26.126  1.00 20.36  ? 89  ILE B CG1 1 
ATOM   4146  C  CG2 . ILE B 1 89  ? 3.231   15.629  28.278  1.00 20.98  ? 89  ILE B CG2 1 
ATOM   4147  C  CD1 . ILE B 1 89  ? 0.789   16.125  26.121  1.00 21.87  ? 89  ILE B CD1 1 
ATOM   4148  N  N   . ILE B 1 90  ? 4.692   12.400  28.932  1.00 26.31  ? 90  ILE B N   1 
ATOM   4149  C  CA  . ILE B 1 90  ? 5.128   11.673  30.122  1.00 24.95  ? 90  ILE B CA  1 
ATOM   4150  C  C   . ILE B 1 90  ? 5.698   12.686  31.111  1.00 24.79  ? 90  ILE B C   1 
ATOM   4151  O  O   . ILE B 1 90  ? 6.642   13.413  30.782  1.00 26.36  ? 90  ILE B O   1 
ATOM   4152  C  CB  . ILE B 1 90  ? 6.174   10.600  29.769  1.00 21.19  ? 90  ILE B CB  1 
ATOM   4153  C  CG1 . ILE B 1 90  ? 5.657   9.660   28.663  1.00 21.02  ? 90  ILE B CG1 1 
ATOM   4154  C  CG2 . ILE B 1 90  ? 6.659   9.836   31.036  1.00 24.22  ? 90  ILE B CG2 1 
ATOM   4155  C  CD1 . ILE B 1 90  ? 4.249   9.068   28.945  1.00 22.76  ? 90  ILE B CD1 1 
ATOM   4156  N  N   . PHE B 1 91  ? 5.136   12.734  32.317  1.00 21.90  ? 91  PHE B N   1 
ATOM   4157  C  CA  . PHE B 1 91  ? 5.628   13.604  33.377  1.00 23.45  ? 91  PHE B CA  1 
ATOM   4158  C  C   . PHE B 1 91  ? 6.377   12.795  34.428  1.00 28.09  ? 91  PHE B C   1 
ATOM   4159  O  O   . PHE B 1 91  ? 5.870   11.778  34.936  1.00 25.78  ? 91  PHE B O   1 
ATOM   4160  C  CB  . PHE B 1 91  ? 4.486   14.376  34.025  1.00 24.81  ? 91  PHE B CB  1 
ATOM   4161  C  CG  . PHE B 1 91  ? 4.888   15.132  35.253  1.00 25.54  ? 91  PHE B CG  1 
ATOM   4162  C  CD1 . PHE B 1 91  ? 5.552   16.344  35.151  1.00 28.73  ? 91  PHE B CD1 1 
ATOM   4163  C  CD2 . PHE B 1 91  ? 4.564   14.659  36.515  1.00 29.95  ? 91  PHE B CD2 1 
ATOM   4164  C  CE1 . PHE B 1 91  ? 5.902   17.067  36.296  1.00 28.54  ? 91  PHE B CE1 1 
ATOM   4165  C  CE2 . PHE B 1 91  ? 4.909   15.375  37.641  1.00 26.77  ? 91  PHE B CE2 1 
ATOM   4166  C  CZ  . PHE B 1 91  ? 5.577   16.581  37.523  1.00 31.31  ? 91  PHE B CZ  1 
ATOM   4167  N  N   . VAL B 1 92  ? 7.578   13.249  34.757  1.00 26.73  ? 92  VAL B N   1 
ATOM   4168  C  CA  . VAL B 1 92  ? 8.409   12.619  35.774  1.00 29.12  ? 92  VAL B CA  1 
ATOM   4169  C  C   . VAL B 1 92  ? 8.497   13.576  36.962  1.00 29.26  ? 92  VAL B C   1 
ATOM   4170  O  O   . VAL B 1 92  ? 9.046   14.678  36.827  1.00 31.55  ? 92  VAL B O   1 
ATOM   4171  C  CB  . VAL B 1 92  ? 9.796   12.266  35.228  1.00 29.98  ? 92  VAL B CB  1 
ATOM   4172  C  CG1 . VAL B 1 92  ? 10.707  11.798  36.362  1.00 31.58  ? 92  VAL B CG1 1 
ATOM   4173  C  CG2 . VAL B 1 92  ? 9.653   11.163  34.175  1.00 24.28  ? 92  VAL B CG2 1 
ATOM   4174  N  N   . PRO B 1 93  ? 7.945   13.219  38.120  1.00 31.40  ? 93  PRO B N   1 
ATOM   4175  C  CA  . PRO B 1 93  ? 8.034   14.095  39.302  1.00 29.33  ? 93  PRO B CA  1 
ATOM   4176  C  C   . PRO B 1 93  ? 9.480   14.225  39.746  1.00 35.42  ? 93  PRO B C   1 
ATOM   4177  O  O   . PRO B 1 93  ? 10.168  13.229  39.961  1.00 31.05  ? 93  PRO B O   1 
ATOM   4178  C  CB  . PRO B 1 93  ? 7.186   13.362  40.349  1.00 32.44  ? 93  PRO B CB  1 
ATOM   4179  C  CG  . PRO B 1 93  ? 6.307   12.445  39.566  1.00 33.21  ? 93  PRO B CG  1 
ATOM   4180  C  CD  . PRO B 1 93  ? 7.130   12.020  38.383  1.00 31.95  ? 93  PRO B CD  1 
ATOM   4181  N  N   . LEU B 1 94  ? 9.954   15.467  39.837  1.00 34.27  ? 94  LEU B N   1 
ATOM   4182  C  CA  . LEU B 1 94  ? 11.297  15.720  40.340  1.00 32.83  ? 94  LEU B CA  1 
ATOM   4183  C  C   . LEU B 1 94  ? 11.378  17.174  40.763  1.00 35.51  ? 94  LEU B C   1 
ATOM   4184  O  O   . LEU B 1 94  ? 11.520  18.069  39.914  1.00 33.34  ? 94  LEU B O   1 
ATOM   4185  C  CB  . LEU B 1 94  ? 12.352  15.393  39.297  1.00 30.50  ? 94  LEU B CB  1 
ATOM   4186  C  CG  . LEU B 1 94  ? 13.807  15.641  39.671  1.00 31.81  ? 94  LEU B CG  1 
ATOM   4187  C  CD1 . LEU B 1 94  ? 14.344  14.532  40.540  1.00 27.91  ? 94  LEU B CD1 1 
ATOM   4188  C  CD2 . LEU B 1 94  ? 14.617  15.746  38.389  1.00 37.60  ? 94  LEU B CD2 1 
ATOM   4189  N  N   . PRO B 1 95  ? 11.242  17.457  42.054  1.00 33.59  ? 95  PRO B N   1 
ATOM   4190  C  CA  . PRO B 1 95  ? 11.309  18.854  42.498  1.00 31.02  ? 95  PRO B CA  1 
ATOM   4191  C  C   . PRO B 1 95  ? 12.621  19.496  42.058  1.00 28.61  ? 95  PRO B C   1 
ATOM   4192  O  O   . PRO B 1 95  ? 13.693  18.902  42.166  1.00 31.76  ? 95  PRO B O   1 
ATOM   4193  C  CB  . PRO B 1 95  ? 11.178  18.757  44.032  1.00 34.93  ? 95  PRO B CB  1 
ATOM   4194  C  CG  . PRO B 1 95  ? 11.350  17.297  44.378  1.00 40.27  ? 95  PRO B CG  1 
ATOM   4195  C  CD  . PRO B 1 95  ? 10.952  16.519  43.152  1.00 34.60  ? 95  PRO B CD  1 
ATOM   4196  N  N   . GLY B 1 96  ? 12.524  20.708  41.516  1.00 31.28  ? 96  GLY B N   1 
ATOM   4197  C  CA  . GLY B 1 96  ? 13.668  21.411  40.990  1.00 28.93  ? 96  GLY B CA  1 
ATOM   4198  C  C   . GLY B 1 96  ? 13.945  21.121  39.530  1.00 34.98  ? 96  GLY B C   1 
ATOM   4199  O  O   . GLY B 1 96  ? 14.524  21.966  38.833  1.00 30.83  ? 96  GLY B O   1 
ATOM   4200  N  N   . GLY B 1 97  ? 13.531  19.948  39.052  1.00 30.00  ? 97  GLY B N   1 
ATOM   4201  C  CA  . GLY B 1 97  ? 13.655  19.615  37.646  1.00 35.97  ? 97  GLY B CA  1 
ATOM   4202  C  C   . GLY B 1 97  ? 15.074  19.281  37.216  1.00 36.39  ? 97  GLY B C   1 
ATOM   4203  O  O   . GLY B 1 97  ? 15.902  18.799  37.994  1.00 34.90  ? 97  GLY B O   1 
ATOM   4204  N  N   . LEU B 1 98  ? 15.340  19.521  35.938  1.00 30.50  ? 98  LEU B N   1 
ATOM   4205  C  CA  . LEU B 1 98  ? 16.618  19.191  35.335  1.00 28.21  ? 98  LEU B CA  1 
ATOM   4206  C  C   . LEU B 1 98  ? 17.395  20.458  35.003  1.00 30.10  ? 98  LEU B C   1 
ATOM   4207  O  O   . LEU B 1 98  ? 16.795  21.489  34.667  1.00 30.05  ? 98  LEU B O   1 
ATOM   4208  C  CB  . LEU B 1 98  ? 16.431  18.378  34.044  1.00 27.83  ? 98  LEU B CB  1 
ATOM   4209  C  CG  . LEU B 1 98  ? 15.692  17.043  34.094  1.00 30.44  ? 98  LEU B CG  1 
ATOM   4210  C  CD1 . LEU B 1 98  ? 15.409  16.533  32.668  1.00 28.93  ? 98  LEU B CD1 1 
ATOM   4211  C  CD2 . LEU B 1 98  ? 16.476  16.013  34.900  1.00 27.32  ? 98  LEU B CD2 1 
ATOM   4212  N  N   . PRO B 1 99  ? 18.729  20.409  35.058  1.00 32.43  ? 99  PRO B N   1 
ATOM   4213  C  CA  . PRO B 1 99  ? 19.533  21.512  34.523  1.00 26.70  ? 99  PRO B CA  1 
ATOM   4214  C  C   . PRO B 1 99  ? 19.431  21.605  33.013  1.00 29.76  ? 99  PRO B C   1 
ATOM   4215  O  O   . PRO B 1 99  ? 19.148  20.628  32.315  1.00 36.49  ? 99  PRO B O   1 
ATOM   4216  C  CB  . PRO B 1 99  ? 20.964  21.137  34.921  1.00 29.69  ? 99  PRO B CB  1 
ATOM   4217  C  CG  . PRO B 1 99  ? 20.945  19.620  34.954  1.00 31.86  ? 99  PRO B CG  1 
ATOM   4218  C  CD  . PRO B 1 99  ? 19.567  19.263  35.478  1.00 32.34  ? 99  PRO B CD  1 
ATOM   4219  N  N   . ASP B 1 100 ? 19.751  22.793  32.511  1.00 29.37  ? 100 ASP B N   1 
ATOM   4220  C  CA  . ASP B 1 100 ? 19.887  23.005  31.075  1.00 32.38  ? 100 ASP B CA  1 
ATOM   4221  C  C   . ASP B 1 100 ? 20.879  22.027  30.468  1.00 32.84  ? 100 ASP B C   1 
ATOM   4222  O  O   . ASP B 1 100 ? 21.861  21.627  31.098  1.00 38.04  ? 100 ASP B O   1 
ATOM   4223  C  CB  . ASP B 1 100 ? 20.364  24.424  30.803  1.00 33.00  ? 100 ASP B CB  1 
ATOM   4224  C  CG  . ASP B 1 100 ? 19.246  25.345  30.480  1.00 34.07  ? 100 ASP B CG  1 
ATOM   4225  O  OD1 . ASP B 1 100 ? 18.278  24.891  29.826  1.00 35.99  ? 100 ASP B OD1 1 
ATOM   4226  O  OD2 . ASP B 1 100 ? 19.330  26.512  30.890  1.00 34.34  ? 100 ASP B OD2 1 
ATOM   4227  N  N   . GLY B 1 101 ? 20.631  21.649  29.239  1.00 28.17  ? 101 GLY B N   1 
ATOM   4228  C  CA  . GLY B 1 101 ? 21.607  20.889  28.507  1.00 31.33  ? 101 GLY B CA  1 
ATOM   4229  C  C   . GLY B 1 101 ? 20.965  19.758  27.751  1.00 34.46  ? 101 GLY B C   1 
ATOM   4230  O  O   . GLY B 1 101 ? 19.742  19.656  27.638  1.00 29.26  ? 101 GLY B O   1 
ATOM   4231  N  N   . VAL B 1 102 ? 21.815  18.926  27.221  1.00 30.56  ? 102 VAL B N   1 
ATOM   4232  C  CA  . VAL B 1 102 ? 21.413  17.686  26.586  1.00 29.42  ? 102 VAL B CA  1 
ATOM   4233  C  C   . VAL B 1 102 ? 21.450  16.607  27.646  1.00 34.11  ? 102 VAL B C   1 
ATOM   4234  O  O   . VAL B 1 102 ? 22.364  16.563  28.477  1.00 28.67  ? 102 VAL B O   1 
ATOM   4235  C  CB  . VAL B 1 102 ? 22.337  17.348  25.402  1.00 32.86  ? 102 VAL B CB  1 
ATOM   4236  C  CG1 . VAL B 1 102 ? 21.754  16.215  24.571  1.00 32.66  ? 102 VAL B CG1 1 
ATOM   4237  C  CG2 . VAL B 1 102 ? 22.556  18.570  24.566  1.00 28.64  ? 102 VAL B CG2 1 
ATOM   4238  N  N   . HIS B 1 103 ? 20.427  15.759  27.647  1.00 31.99  ? 103 HIS B N   1 
ATOM   4239  C  CA  . HIS B 1 103 ? 20.327  14.672  28.601  1.00 31.04  ? 103 HIS B CA  1 
ATOM   4240  C  C   . HIS B 1 103 ? 20.127  13.380  27.837  1.00 32.24  ? 103 HIS B C   1 
ATOM   4241  O  O   . HIS B 1 103 ? 19.446  13.346  26.806  1.00 30.34  ? 103 HIS B O   1 
ATOM   4242  C  CB  . HIS B 1 103 ? 19.186  14.893  29.592  1.00 29.91  ? 103 HIS B CB  1 
ATOM   4243  C  CG  . HIS B 1 103 ? 19.306  16.166  30.369  1.00 31.32  ? 103 HIS B CG  1 
ATOM   4244  N  ND1 . HIS B 1 103 ? 20.182  16.310  31.422  1.00 33.41  ? 103 HIS B ND1 1 
ATOM   4245  C  CD2 . HIS B 1 103 ? 18.677  17.360  30.236  1.00 32.08  ? 103 HIS B CD2 1 
ATOM   4246  C  CE1 . HIS B 1 103 ? 20.083  17.538  31.907  1.00 30.21  ? 103 HIS B CE1 1 
ATOM   4247  N  NE2 . HIS B 1 103 ? 19.181  18.196  31.202  1.00 31.22  ? 103 HIS B NE2 1 
ATOM   4248  N  N   . GLU B 1 104 ? 20.711  12.318  28.355  1.00 28.26  ? 104 GLU B N   1 
ATOM   4249  C  CA  . GLU B 1 104 ? 20.661  11.022  27.711  1.00 34.20  ? 104 GLU B CA  1 
ATOM   4250  C  C   . GLU B 1 104 ? 19.496  10.243  28.329  1.00 34.42  ? 104 GLU B C   1 
ATOM   4251  O  O   . GLU B 1 104 ? 19.655  9.511   29.308  1.00 33.86  ? 104 GLU B O   1 
ATOM   4252  C  CB  . GLU B 1 104 ? 22.019  10.358  27.862  1.00 35.21  ? 104 GLU B CB  1 
ATOM   4253  C  CG  . GLU B 1 104 ? 22.123  8.956   27.412  1.00 33.27  ? 104 GLU B CG  1 
ATOM   4254  C  CD  . GLU B 1 104 ? 23.208  8.252   28.173  1.00 41.63  ? 104 GLU B CD  1 
ATOM   4255  O  OE1 . GLU B 1 104 ? 24.365  8.721   28.092  1.00 50.89  ? 104 GLU B OE1 1 
ATOM   4256  O  OE2 . GLU B 1 104 ? 22.908  7.260   28.866  1.00 42.41  ? 104 GLU B OE2 1 
ATOM   4257  N  N   . LEU B 1 105 ? 18.310  10.405  27.729  1.00 29.05  ? 105 LEU B N   1 
ATOM   4258  C  CA  . LEU B 1 105 ? 17.066  9.829   28.230  1.00 30.44  ? 105 LEU B CA  1 
ATOM   4259  C  C   . LEU B 1 105 ? 16.904  8.397   27.733  1.00 35.43  ? 105 LEU B C   1 
ATOM   4260  O  O   . LEU B 1 105 ? 16.920  8.134   26.516  1.00 32.88  ? 105 LEU B O   1 
ATOM   4261  C  CB  . LEU B 1 105 ? 15.871  10.680  27.803  1.00 30.05  ? 105 LEU B CB  1 
ATOM   4262  C  CG  . LEU B 1 105 ? 14.508  10.541  28.510  1.00 29.85  ? 105 LEU B CG  1 
ATOM   4263  C  CD1 . LEU B 1 105 ? 14.669  10.424  30.003  1.00 29.92  ? 105 LEU B CD1 1 
ATOM   4264  C  CD2 . LEU B 1 105 ? 13.608  11.733  28.202  1.00 26.95  ? 105 LEU B CD2 1 
ATOM   4265  N  N   . SER B 1 106 ? 16.739  7.481   28.680  1.00 30.04  ? 106 SER B N   1 
ATOM   4266  C  CA  . SER B 1 106 ? 16.460  6.079   28.410  1.00 33.45  ? 106 SER B CA  1 
ATOM   4267  C  C   . SER B 1 106 ? 15.076  5.748   28.945  1.00 28.68  ? 106 SER B C   1 
ATOM   4268  O  O   . SER B 1 106 ? 14.765  6.058   30.097  1.00 30.76  ? 106 SER B O   1 
ATOM   4269  C  CB  . SER B 1 106 ? 17.511  5.178   29.061  1.00 33.63  ? 106 SER B CB  1 
ATOM   4270  O  OG  . SER B 1 106 ? 18.818  5.571   28.668  1.00 43.88  ? 106 SER B OG  1 
ATOM   4271  N  N   . ILE B 1 107 ? 14.237  5.164   28.103  1.00 29.61  ? 107 ILE B N   1 
ATOM   4272  C  CA  . ILE B 1 107 ? 12.885  4.817   28.519  1.00 30.06  ? 107 ILE B CA  1 
ATOM   4273  C  C   . ILE B 1 107 ? 12.694  3.322   28.349  1.00 28.41  ? 107 ILE B C   1 
ATOM   4274  O  O   . ILE B 1 107 ? 13.314  2.685   27.491  1.00 35.55  ? 107 ILE B O   1 
ATOM   4275  C  CB  . ILE B 1 107 ? 11.785  5.583   27.749  1.00 26.18  ? 107 ILE B CB  1 
ATOM   4276  C  CG1 . ILE B 1 107 ? 11.840  5.254   26.265  1.00 29.54  ? 107 ILE B CG1 1 
ATOM   4277  C  CG2 . ILE B 1 107 ? 11.894  7.093   27.962  1.00 26.30  ? 107 ILE B CG2 1 
ATOM   4278  C  CD1 . ILE B 1 107 ? 10.673  5.839   25.488  1.00 28.92  ? 107 ILE B CD1 1 
ATOM   4279  N  N   . GLU B 1 108 ? 11.809  2.765   29.175  1.00 27.41  ? 108 GLU B N   1 
ATOM   4280  C  CA  . GLU B 1 108 ? 11.378  1.375   29.070  1.00 32.68  ? 108 GLU B CA  1 
ATOM   4281  C  C   . GLU B 1 108 ? 9.847   1.421   29.058  1.00 31.20  ? 108 GLU B C   1 
ATOM   4282  O  O   . GLU B 1 108 ? 9.203   1.464   30.108  1.00 30.88  ? 108 GLU B O   1 
ATOM   4283  C  CB  . GLU B 1 108 ? 11.948  0.538   30.220  1.00 35.63  ? 108 GLU B CB  1 
ATOM   4284  C  CG  . GLU B 1 108 ? 11.352  -0.868  30.347  1.00 44.04  ? 108 GLU B CG  1 
ATOM   4285  C  CD  . GLU B 1 108 ? 12.096  -1.726  31.361  1.00 51.31  ? 108 GLU B CD  1 
ATOM   4286  O  OE1 . GLU B 1 108 ? 12.538  -1.179  32.404  1.00 40.23  ? 108 GLU B OE1 1 
ATOM   4287  O  OE2 . GLU B 1 108 ? 12.253  -2.944  31.100  1.00 52.68  ? 108 GLU B OE2 1 
ATOM   4288  N  N   . LEU B 1 109 ? 9.275   1.475   27.859  1.00 29.20  ? 109 LEU B N   1 
ATOM   4289  C  CA  . LEU B 1 109 ? 7.835   1.557   27.665  1.00 25.81  ? 109 LEU B CA  1 
ATOM   4290  C  C   . LEU B 1 109 ? 7.287   0.161   27.442  1.00 26.56  ? 109 LEU B C   1 
ATOM   4291  O  O   . LEU B 1 109 ? 7.853   -0.595  26.651  1.00 30.84  ? 109 LEU B O   1 
ATOM   4292  C  CB  . LEU B 1 109 ? 7.513   2.422   26.450  1.00 25.73  ? 109 LEU B CB  1 
ATOM   4293  C  CG  . LEU B 1 109 ? 6.065   2.336   25.996  1.00 25.10  ? 109 LEU B CG  1 
ATOM   4294  C  CD1 . LEU B 1 109 ? 5.239   3.176   26.964  1.00 27.70  ? 109 LEU B CD1 1 
ATOM   4295  C  CD2 . LEU B 1 109 ? 5.927   2.822   24.541  1.00 21.78  ? 109 LEU B CD2 1 
ATOM   4296  N  N   . ARG B 1 110 ? 6.190   -0.171  28.128  1.00 25.34  ? 110 ARG B N   1 
ATOM   4297  C  CA  . ARG B 1 110 ? 5.552   -1.476  28.030  1.00 28.30  ? 110 ARG B CA  1 
ATOM   4298  C  C   . ARG B 1 110 ? 4.118   -1.316  27.554  1.00 24.65  ? 110 ARG B C   1 
ATOM   4299  O  O   . ARG B 1 110 ? 3.425   -0.400  27.992  1.00 25.11  ? 110 ARG B O   1 
ATOM   4300  C  CB  . ARG B 1 110 ? 5.554   -2.202  29.377  1.00 29.75  ? 110 ARG B CB  1 
ATOM   4301  C  CG  . ARG B 1 110 ? 6.897   -2.263  30.055  1.00 33.64  ? 110 ARG B CG  1 
ATOM   4302  C  CD  . ARG B 1 110 ? 6.792   -2.862  31.446  1.00 36.52  ? 110 ARG B CD  1 
ATOM   4303  N  NE  . ARG B 1 110 ? 8.085   -3.401  31.845  1.00 43.85  ? 110 ARG B NE  1 
ATOM   4304  C  CZ  . ARG B 1 110 ? 8.448   -3.661  33.092  1.00 44.60  ? 110 ARG B CZ  1 
ATOM   4305  N  NH1 . ARG B 1 110 ? 7.609   -3.510  34.108  1.00 45.08  ? 110 ARG B NH1 1 
ATOM   4306  N  NH2 . ARG B 1 110 ? 9.688   -4.080  33.328  1.00 47.04  ? 110 ARG B NH2 1 
ATOM   4307  N  N   . LEU B 1 111 ? 3.674   -2.226  26.673  1.00 23.24  ? 111 LEU B N   1 
ATOM   4308  C  CA  . LEU B 1 111 ? 2.340   -2.206  26.086  1.00 23.33  ? 111 LEU B CA  1 
ATOM   4309  C  C   . LEU B 1 111 ? 1.773   -3.624  26.092  1.00 28.74  ? 111 LEU B C   1 
ATOM   4310  O  O   . LEU B 1 111 ? 2.505   -4.592  25.892  1.00 30.34  ? 111 LEU B O   1 
ATOM   4311  C  CB  . LEU B 1 111 ? 2.360   -1.672  24.627  1.00 23.56  ? 111 LEU B CB  1 
ATOM   4312  C  CG  . LEU B 1 111 ? 2.707   -0.205  24.313  1.00 27.92  ? 111 LEU B CG  1 
ATOM   4313  C  CD1 . LEU B 1 111 ? 2.442   0.095   22.836  1.00 20.99  ? 111 LEU B CD1 1 
ATOM   4314  C  CD2 . LEU B 1 111 ? 1.919   0.769   25.208  1.00 25.32  ? 111 LEU B CD2 1 
ATOM   4315  N  N   . ARG B 1 112 ? 0.462   -3.745  26.301  1.00 24.17  ? 112 ARG B N   1 
ATOM   4316  C  CA  . ARG B 1 112 ? -0.209  -5.043  26.315  1.00 31.30  ? 112 ARG B CA  1 
ATOM   4317  C  C   . ARG B 1 112 ? -0.965  -5.217  25.004  1.00 30.20  ? 112 ARG B C   1 
ATOM   4318  O  O   . ARG B 1 112 ? -1.965  -4.529  24.770  1.00 26.71  ? 112 ARG B O   1 
ATOM   4319  C  CB  . ARG B 1 112 ? -1.168  -5.163  27.496  1.00 25.28  ? 112 ARG B CB  1 
ATOM   4320  C  CG  . ARG B 1 112 ? -0.520  -5.127  28.852  1.00 22.13  ? 112 ARG B CG  1 
ATOM   4321  C  CD  . ARG B 1 112 ? -1.458  -5.686  29.929  1.00 25.83  ? 112 ARG B CD  1 
ATOM   4322  N  NE  . ARG B 1 112 ? -2.811  -5.149  29.890  1.00 24.91  ? 112 ARG B NE  1 
ATOM   4323  C  CZ  . ARG B 1 112 ? -3.150  -3.953  30.367  1.00 31.99  ? 112 ARG B CZ  1 
ATOM   4324  N  NH1 . ARG B 1 112 ? -2.237  -3.103  30.819  1.00 26.83  ? 112 ARG B NH1 1 
ATOM   4325  N  NH2 . ARG B 1 112 ? -4.432  -3.595  30.385  1.00 25.61  ? 112 ARG B NH2 1 
ATOM   4326  N  N   . MET B 1 113 ? -0.484  -6.134  24.152  1.00 31.17  ? 113 MET B N   1 
ATOM   4327  C  CA  . MET B 1 113 ? -1.182  -6.525  22.933  1.00 31.81  ? 113 MET B CA  1 
ATOM   4328  C  C   . MET B 1 113 ? -1.837  -7.877  23.201  1.00 35.94  ? 113 MET B C   1 
ATOM   4329  O  O   . MET B 1 113 ? -1.137  -8.882  23.373  1.00 35.42  ? 113 MET B O   1 
ATOM   4330  C  CB  . MET B 1 113 ? -0.224  -6.622  21.752  1.00 35.13  ? 113 MET B CB  1 
ATOM   4331  C  CG  . MET B 1 113 ? 1.108   -5.945  22.005  1.00 37.95  ? 113 MET B CG  1 
ATOM   4332  S  SD  . MET B 1 113 ? 1.046   -4.156  22.203  1.00 40.53  ? 113 MET B SD  1 
ATOM   4333  C  CE  . MET B 1 113 ? 1.176   -3.560  20.518  1.00 39.59  ? 113 MET B CE  1 
ATOM   4334  N  N   . SER B 1 114 ? -3.175  -7.910  23.209  1.00 33.87  ? 114 SER B N   1 
ATOM   4335  C  CA  . SER B 1 114 ? -3.889  -9.136  23.590  1.00 35.15  ? 114 SER B CA  1 
ATOM   4336  C  C   . SER B 1 114 ? -3.680  -10.282 22.595  1.00 34.56  ? 114 SER B C   1 
ATOM   4337  O  O   . SER B 1 114 ? -3.787  -11.453 22.971  1.00 41.02  ? 114 SER B O   1 
ATOM   4338  C  CB  . SER B 1 114 ? -5.383  -8.851  23.739  1.00 26.47  ? 114 SER B CB  1 
ATOM   4339  O  OG  . SER B 1 114 ? -5.634  -7.687  24.511  1.00 31.19  ? 114 SER B OG  1 
ATOM   4340  N  N   . TYR B 1 115 ? -3.404  -9.981  21.338  1.00 30.20  ? 115 TYR B N   1 
ATOM   4341  C  CA  . TYR B 1 115 ? -3.277  -11.001 20.312  1.00 33.50  ? 115 TYR B CA  1 
ATOM   4342  C  C   . TYR B 1 115 ? -1.924  -11.699 20.326  1.00 38.43  ? 115 TYR B C   1 
ATOM   4343  O  O   . TYR B 1 115 ? -1.660  -12.535 19.454  1.00 36.38  ? 115 TYR B O   1 
ATOM   4344  C  CB  . TYR B 1 115 ? -3.509  -10.372 18.938  1.00 36.16  ? 115 TYR B CB  1 
ATOM   4345  C  CG  . TYR B 1 115 ? -2.720  -9.088  18.709  1.00 36.77  ? 115 TYR B CG  1 
ATOM   4346  C  CD1 . TYR B 1 115 ? -3.233  -7.846  19.078  1.00 32.78  ? 115 TYR B CD1 1 
ATOM   4347  C  CD2 . TYR B 1 115 ? -1.462  -9.122  18.131  1.00 40.40  ? 115 TYR B CD2 1 
ATOM   4348  C  CE1 . TYR B 1 115 ? -2.513  -6.688  18.866  1.00 29.71  ? 115 TYR B CE1 1 
ATOM   4349  C  CE2 . TYR B 1 115 ? -0.735  -7.959  17.918  1.00 38.26  ? 115 TYR B CE2 1 
ATOM   4350  C  CZ  . TYR B 1 115 ? -1.263  -6.749  18.288  1.00 39.04  ? 115 TYR B CZ  1 
ATOM   4351  O  OH  . TYR B 1 115 ? -0.524  -5.597  18.066  1.00 40.84  ? 115 TYR B OH  1 
ATOM   4352  N  N   . ILE B 1 116 ? -1.047  -11.353 21.258  1.00 41.18  ? 116 ILE B N   1 
ATOM   4353  C  CA  . ILE B 1 116 ? 0.267   -11.978 21.329  1.00 37.39  ? 116 ILE B CA  1 
ATOM   4354  C  C   . ILE B 1 116 ? 0.287   -12.865 22.565  1.00 34.40  ? 116 ILE B C   1 
ATOM   4355  O  O   . ILE B 1 116 ? -0.263  -12.477 23.606  1.00 37.94  ? 116 ILE B O   1 
ATOM   4356  C  CB  . ILE B 1 116 ? 1.386   -10.930 21.351  1.00 31.78  ? 116 ILE B CB  1 
ATOM   4357  C  CG1 . ILE B 1 116 ? 1.378   -10.116 20.058  1.00 35.91  ? 116 ILE B CG1 1 
ATOM   4358  C  CG2 . ILE B 1 116 ? 2.720   -11.584 21.578  1.00 34.76  ? 116 ILE B CG2 1 
ATOM   4359  C  CD1 . ILE B 1 116 ? 1.726   -10.926 18.830  1.00 42.52  ? 116 ILE B CD1 1 
ATOM   4360  N  N   . PRO B 1 117 ? 0.887   -14.057 22.488  1.00 38.69  ? 117 PRO B N   1 
ATOM   4361  C  CA  . PRO B 1 117 ? 0.906   -14.970 23.645  1.00 37.71  ? 117 PRO B CA  1 
ATOM   4362  C  C   . PRO B 1 117 ? 1.508   -14.350 24.905  1.00 40.77  ? 117 PRO B C   1 
ATOM   4363  O  O   . PRO B 1 117 ? 2.497   -13.613 24.851  1.00 39.62  ? 117 PRO B O   1 
ATOM   4364  C  CB  . PRO B 1 117 ? 1.756   -16.144 23.143  1.00 40.40  ? 117 PRO B CB  1 
ATOM   4365  C  CG  . PRO B 1 117 ? 1.549   -16.148 21.662  1.00 42.09  ? 117 PRO B CG  1 
ATOM   4366  C  CD  . PRO B 1 117 ? 1.407   -14.697 21.260  1.00 35.07  ? 117 PRO B CD  1 
ATOM   4367  N  N   . GLN B 1 118 ? 0.914   -14.698 26.052  1.00 34.11  ? 118 GLN B N   1 
ATOM   4368  C  CA  . GLN B 1 118 ? 1.339   -14.155 27.349  1.00 44.23  ? 118 GLN B CA  1 
ATOM   4369  C  C   . GLN B 1 118 ? 2.839   -14.293 27.586  1.00 43.53  ? 118 GLN B C   1 
ATOM   4370  O  O   . GLN B 1 118 ? 3.463   -13.416 28.196  1.00 44.64  ? 118 GLN B O   1 
ATOM   4371  C  CB  . GLN B 1 118 ? 0.580   -14.848 28.484  1.00 45.07  ? 118 GLN B CB  1 
ATOM   4372  C  CG  . GLN B 1 118 ? -0.801  -14.285 28.712  1.00 47.41  ? 118 GLN B CG  1 
ATOM   4373  C  CD  . GLN B 1 118 ? -0.931  -13.671 30.081  1.00 58.04  ? 118 GLN B CD  1 
ATOM   4374  O  OE1 . GLN B 1 118 ? 0.022   -13.690 30.865  1.00 58.43  ? 118 GLN B OE1 1 
ATOM   4375  N  NE2 . GLN B 1 118 ? -2.100  -13.091 30.373  1.00 51.37  ? 118 GLN B NE2 1 
ATOM   4376  N  N   . GLU B 1 119 ? 3.434   -15.393 27.128  1.00 40.60  ? 119 GLU B N   1 
ATOM   4377  C  CA  . GLU B 1 119 ? 4.848   -15.635 27.378  1.00 42.59  ? 119 GLU B CA  1 
ATOM   4378  C  C   . GLU B 1 119 ? 5.741   -14.643 26.636  1.00 44.17  ? 119 GLU B C   1 
ATOM   4379  O  O   . GLU B 1 119 ? 6.959   -14.614 26.871  1.00 40.20  ? 119 GLU B O   1 
ATOM   4380  C  CB  . GLU B 1 119 ? 5.177   -17.089 27.007  1.00 37.81  ? 119 GLU B CB  1 
ATOM   4381  C  CG  . GLU B 1 119 ? 4.498   -18.131 27.930  1.00 38.20  ? 119 GLU B CG  1 
ATOM   4382  C  CD  . GLU B 1 119 ? 3.170   -18.636 27.370  1.00 47.37  ? 119 GLU B CD  1 
ATOM   4383  O  OE1 . GLU B 1 119 ? 2.706   -18.083 26.344  1.00 42.65  ? 119 GLU B OE1 1 
ATOM   4384  O  OE2 . GLU B 1 119 ? 2.590   -19.591 27.944  1.00 47.76  ? 119 GLU B OE2 1 
ATOM   4385  N  N   . HIS B 1 120 ? 5.157   -13.810 25.769  1.00 42.02  ? 120 HIS B N   1 
ATOM   4386  C  CA  . HIS B 1 120 ? 5.891   -12.803 25.014  1.00 38.78  ? 120 HIS B CA  1 
ATOM   4387  C  C   . HIS B 1 120 ? 5.381   -11.391 25.305  1.00 39.39  ? 120 HIS B C   1 
ATOM   4388  O  O   . HIS B 1 120 ? 5.586   -10.475 24.506  1.00 40.12  ? 120 HIS B O   1 
ATOM   4389  C  CB  . HIS B 1 120 ? 5.820   -13.131 23.521  1.00 36.48  ? 120 HIS B CB  1 
ATOM   4390  C  CG  . HIS B 1 120 ? 6.577   -14.367 23.144  1.00 41.26  ? 120 HIS B CG  1 
ATOM   4391  N  ND1 . HIS B 1 120 ? 5.993   -15.429 22.482  1.00 46.78  ? 120 HIS B ND1 1 
ATOM   4392  C  CD2 . HIS B 1 120 ? 7.872   -14.714 23.343  1.00 42.96  ? 120 HIS B CD2 1 
ATOM   4393  C  CE1 . HIS B 1 120 ? 6.895   -16.375 22.286  1.00 44.13  ? 120 HIS B CE1 1 
ATOM   4394  N  NE2 . HIS B 1 120 ? 8.042   -15.968 22.802  1.00 49.00  ? 120 HIS B NE2 1 
ATOM   4395  N  N   . GLN B 1 121 ? 4.750   -11.192 26.455  1.00 42.18  ? 121 GLN B N   1 
ATOM   4396  C  CA  . GLN B 1 121 ? 4.146   -9.928  26.829  1.00 38.92  ? 121 GLN B CA  1 
ATOM   4397  C  C   . GLN B 1 121 ? 4.544   -9.572  28.254  1.00 40.14  ? 121 GLN B C   1 
ATOM   4398  O  O   . GLN B 1 121 ? 4.864   -10.461 29.052  1.00 43.94  ? 121 GLN B O   1 
ATOM   4399  C  CB  . GLN B 1 121 ? 2.617   -10.006 26.717  1.00 34.95  ? 121 GLN B CB  1 
ATOM   4400  C  CG  . GLN B 1 121 ? 2.115   -10.033 25.300  1.00 36.47  ? 121 GLN B CG  1 
ATOM   4401  C  CD  . GLN B 1 121 ? 2.271   -8.691  24.612  1.00 34.88  ? 121 GLN B CD  1 
ATOM   4402  O  OE1 . GLN B 1 121 ? 1.678   -7.684  25.028  1.00 33.26  ? 121 GLN B OE1 1 
ATOM   4403  N  NE2 . GLN B 1 121 ? 3.085   -8.665  23.572  1.00 30.20  ? 121 GLN B NE2 1 
ATOM   4404  N  N   . PRO B 1 122 ? 4.530   -8.276  28.611  1.00 44.07  ? 122 PRO B N   1 
ATOM   4405  C  CA  . PRO B 1 122 ? 4.139   -7.136  27.775  1.00 38.94  ? 122 PRO B CA  1 
ATOM   4406  C  C   . PRO B 1 122 ? 5.138   -6.839  26.677  1.00 34.53  ? 122 PRO B C   1 
ATOM   4407  O  O   . PRO B 1 122 ? 6.311   -7.202  26.809  1.00 35.81  ? 122 PRO B O   1 
ATOM   4408  C  CB  . PRO B 1 122 ? 4.084   -5.978  28.771  1.00 34.94  ? 122 PRO B CB  1 
ATOM   4409  C  CG  . PRO B 1 122 ? 5.077   -6.329  29.788  1.00 39.10  ? 122 PRO B CG  1 
ATOM   4410  C  CD  . PRO B 1 122 ? 4.975   -7.834  29.946  1.00 41.46  ? 122 PRO B CD  1 
ATOM   4411  N  N   . SER B 1 123 ? 4.655   -6.225  25.599  1.00 33.51  ? 123 SER B N   1 
ATOM   4412  C  CA  . SER B 1 123 ? 5.532   -5.719  24.553  1.00 30.85  ? 123 SER B CA  1 
ATOM   4413  C  C   . SER B 1 123 ? 6.382   -4.598  25.126  1.00 30.17  ? 123 SER B C   1 
ATOM   4414  O  O   . SER B 1 123 ? 5.865   -3.711  25.808  1.00 35.35  ? 123 SER B O   1 
ATOM   4415  C  CB  . SER B 1 123 ? 4.707   -5.214  23.368  1.00 32.22  ? 123 SER B CB  1 
ATOM   4416  O  OG  . SER B 1 123 ? 4.340   -6.275  22.500  1.00 32.38  ? 123 SER B OG  1 
ATOM   4417  N  N   . THR B 1 124 ? 7.680   -4.629  24.861  1.00 30.52  ? 124 THR B N   1 
ATOM   4418  C  CA  . THR B 1 124 ? 8.602   -3.714  25.513  1.00 31.94  ? 124 THR B CA  1 
ATOM   4419  C  C   . THR B 1 124 ? 9.492   -3.022  24.490  1.00 32.44  ? 124 THR B C   1 
ATOM   4420  O  O   . THR B 1 124 ? 9.934   -3.627  23.512  1.00 34.97  ? 124 THR B O   1 
ATOM   4421  C  CB  . THR B 1 124 ? 9.427   -4.465  26.570  1.00 35.32  ? 124 THR B CB  1 
ATOM   4422  O  OG1 . THR B 1 124 ? 8.523   -5.054  27.516  1.00 37.36  ? 124 THR B OG1 1 
ATOM   4423  C  CG2 . THR B 1 124 ? 10.333  -3.539  27.315  1.00 38.04  ? 124 THR B CG2 1 
ATOM   4424  N  N   . TYR B 1 125 ? 9.738   -1.740  24.732  1.00 33.20  ? 125 TYR B N   1 
ATOM   4425  C  CA  . TYR B 1 125 ? 10.511  -0.877  23.849  1.00 31.43  ? 125 TYR B CA  1 
ATOM   4426  C  C   . TYR B 1 125 ? 11.511  -0.128  24.719  1.00 28.40  ? 125 TYR B C   1 
ATOM   4427  O  O   . TYR B 1 125 ? 11.124  0.636   25.607  1.00 27.33  ? 125 TYR B O   1 
ATOM   4428  C  CB  . TYR B 1 125 ? 9.593   0.085   23.087  1.00 27.69  ? 125 TYR B CB  1 
ATOM   4429  C  CG  . TYR B 1 125 ? 8.382   -0.580  22.473  1.00 23.85  ? 125 TYR B CG  1 
ATOM   4430  C  CD1 . TYR B 1 125 ? 7.262   -0.860  23.227  1.00 31.63  ? 125 TYR B CD1 1 
ATOM   4431  C  CD2 . TYR B 1 125 ? 8.361   -0.914  21.122  1.00 31.95  ? 125 TYR B CD2 1 
ATOM   4432  C  CE1 . TYR B 1 125 ? 6.155   -1.478  22.667  1.00 31.43  ? 125 TYR B CE1 1 
ATOM   4433  C  CE2 . TYR B 1 125 ? 7.255   -1.521  20.548  1.00 27.57  ? 125 TYR B CE2 1 
ATOM   4434  C  CZ  . TYR B 1 125 ? 6.161   -1.803  21.334  1.00 28.50  ? 125 TYR B CZ  1 
ATOM   4435  O  OH  . TYR B 1 125 ? 5.060   -2.404  20.777  1.00 39.77  ? 125 TYR B OH  1 
ATOM   4436  N  N   . ARG B 1 126 ? 12.790  -0.382  24.495  1.00 29.99  ? 126 ARG B N   1 
ATOM   4437  C  CA  . ARG B 1 126 ? 13.868  0.301   25.190  1.00 31.95  ? 126 ARG B CA  1 
ATOM   4438  C  C   . ARG B 1 126 ? 14.588  1.155   24.161  1.00 31.20  ? 126 ARG B C   1 
ATOM   4439  O  O   . ARG B 1 126 ? 15.141  0.633   23.191  1.00 37.07  ? 126 ARG B O   1 
ATOM   4440  C  CB  . ARG B 1 126 ? 14.841  -0.679  25.852  1.00 28.93  ? 126 ARG B CB  1 
ATOM   4441  C  CG  . ARG B 1 126 ? 14.227  -1.629  26.862  1.00 38.01  ? 126 ARG B CG  1 
ATOM   4442  C  CD  . ARG B 1 126 ? 15.003  -2.945  26.906  1.00 42.75  ? 126 ARG B CD  1 
ATOM   4443  N  NE  . ARG B 1 126 ? 14.250  -4.010  27.558  1.00 51.02  ? 126 ARG B NE  1 
ATOM   4444  C  CZ  . ARG B 1 126 ? 14.090  -4.114  28.872  1.00 51.61  ? 126 ARG B CZ  1 
ATOM   4445  N  NH1 . ARG B 1 126 ? 14.625  -3.235  29.708  1.00 49.32  ? 126 ARG B NH1 1 
ATOM   4446  N  NH2 . ARG B 1 126 ? 13.364  -5.115  29.359  1.00 44.75  ? 126 ARG B NH2 1 
ATOM   4447  N  N   . VAL B 1 127 ? 14.532  2.460   24.340  1.00 34.98  ? 127 VAL B N   1 
ATOM   4448  C  CA  . VAL B 1 127 ? 15.299  3.376   23.521  1.00 30.73  ? 127 VAL B CA  1 
ATOM   4449  C  C   . VAL B 1 127 ? 15.955  4.384   24.444  1.00 29.05  ? 127 VAL B C   1 
ATOM   4450  O  O   . VAL B 1 127 ? 15.447  4.699   25.526  1.00 33.38  ? 127 VAL B O   1 
ATOM   4451  C  CB  . VAL B 1 127 ? 14.435  4.080   22.448  1.00 36.88  ? 127 VAL B CB  1 
ATOM   4452  C  CG1 . VAL B 1 127 ? 13.687  3.063   21.607  1.00 37.88  ? 127 VAL B CG1 1 
ATOM   4453  C  CG2 . VAL B 1 127 ? 13.453  4.999   23.097  1.00 34.74  ? 127 VAL B CG2 1 
ATOM   4454  N  N   . THR B 1 128 ? 17.102  4.876   24.002  1.00 31.84  ? 128 THR B N   1 
ATOM   4455  C  CA  . THR B 1 128 ? 17.877  5.909   24.659  1.00 28.90  ? 128 THR B CA  1 
ATOM   4456  C  C   . THR B 1 128 ? 18.079  7.036   23.664  1.00 31.41  ? 128 THR B C   1 
ATOM   4457  O  O   . THR B 1 128 ? 18.320  6.775   22.485  1.00 33.70  ? 128 THR B O   1 
ATOM   4458  C  CB  . THR B 1 128 ? 19.233  5.360   25.096  1.00 31.07  ? 128 THR B CB  1 
ATOM   4459  O  OG1 . THR B 1 128 ? 19.040  4.212   25.935  1.00 32.37  ? 128 THR B OG1 1 
ATOM   4460  C  CG2 . THR B 1 128 ? 20.042  6.424   25.835  1.00 31.41  ? 128 THR B CG2 1 
ATOM   4461  N  N   . LYS B 1 129 ? 17.994  8.286   24.119  1.00 27.39  ? 129 LYS B N   1 
ATOM   4462  C  CA  . LYS B 1 129 ? 18.252  9.378   23.190  1.00 30.58  ? 129 LYS B CA  1 
ATOM   4463  C  C   . LYS B 1 129 ? 18.753  10.611  23.921  1.00 26.75  ? 129 LYS B C   1 
ATOM   4464  O  O   . LYS B 1 129 ? 18.286  10.931  25.012  1.00 24.59  ? 129 LYS B O   1 
ATOM   4465  C  CB  . LYS B 1 129 ? 16.993  9.741   22.385  1.00 34.80  ? 129 LYS B CB  1 
ATOM   4466  C  CG  . LYS B 1 129 ? 17.200  10.835  21.323  1.00 29.35  ? 129 LYS B CG  1 
ATOM   4467  C  CD  . LYS B 1 129 ? 15.869  11.396  20.845  1.00 27.40  ? 129 LYS B CD  1 
ATOM   4468  C  CE  . LYS B 1 129 ? 16.050  12.449  19.758  1.00 37.35  ? 129 LYS B CE  1 
ATOM   4469  N  NZ  . LYS B 1 129 ? 14.728  12.945  19.286  1.00 30.98  ? 129 LYS B NZ  1 
ATOM   4470  N  N   . HIS B 1 130 ? 19.690  11.312  23.295  1.00 31.31  ? 130 HIS B N   1 
ATOM   4471  C  CA  . HIS B 1 130 ? 20.151  12.596  23.798  1.00 28.65  ? 130 HIS B CA  1 
ATOM   4472  C  C   . HIS B 1 130 ? 19.165  13.647  23.321  1.00 30.78  ? 130 HIS B C   1 
ATOM   4473  O  O   . HIS B 1 130 ? 19.005  13.853  22.108  1.00 28.39  ? 130 HIS B O   1 
ATOM   4474  C  CB  . HIS B 1 130 ? 21.565  12.893  23.301  1.00 37.29  ? 130 HIS B CB  1 
ATOM   4475  C  CG  . HIS B 1 130 ? 22.625  12.043  23.928  1.00 36.81  ? 130 HIS B CG  1 
ATOM   4476  N  ND1 . HIS B 1 130 ? 23.209  10.976  23.273  1.00 39.29  ? 130 HIS B ND1 1 
ATOM   4477  C  CD2 . HIS B 1 130 ? 23.217  12.109  25.143  1.00 37.15  ? 130 HIS B CD2 1 
ATOM   4478  C  CE1 . HIS B 1 130 ? 24.110  10.420  24.062  1.00 33.10  ? 130 HIS B CE1 1 
ATOM   4479  N  NE2 . HIS B 1 130 ? 24.130  11.084  25.204  1.00 40.93  ? 130 HIS B NE2 1 
ATOM   4480  N  N   . VAL B 1 131 ? 18.473  14.284  24.263  1.00 34.45  ? 131 VAL B N   1 
ATOM   4481  C  CA  . VAL B 1 131 ? 17.450  15.276  23.958  1.00 30.45  ? 131 VAL B CA  1 
ATOM   4482  C  C   . VAL B 1 131 ? 17.759  16.509  24.779  1.00 31.02  ? 131 VAL B C   1 
ATOM   4483  O  O   . VAL B 1 131 ? 18.205  16.393  25.930  1.00 33.69  ? 131 VAL B O   1 
ATOM   4484  C  CB  . VAL B 1 131 ? 16.023  14.775  24.268  1.00 29.30  ? 131 VAL B CB  1 
ATOM   4485  C  CG1 . VAL B 1 131 ? 15.504  13.938  23.143  1.00 31.78  ? 131 VAL B CG1 1 
ATOM   4486  C  CG2 . VAL B 1 131 ? 15.991  13.993  25.599  1.00 26.21  ? 131 VAL B CG2 1 
ATOM   4487  N  N   . THR B 1 132 ? 17.525  17.689  24.192  1.00 24.70  ? 132 THR B N   1 
ATOM   4488  C  CA  . THR B 1 132 ? 17.901  18.952  24.814  1.00 26.89  ? 132 THR B CA  1 
ATOM   4489  C  C   . THR B 1 132 ? 16.695  19.579  25.487  1.00 27.74  ? 132 THR B C   1 
ATOM   4490  O  O   . THR B 1 132 ? 15.687  19.871  24.833  1.00 29.02  ? 132 THR B O   1 
ATOM   4491  C  CB  . THR B 1 132 ? 18.499  19.929  23.799  1.00 27.05  ? 132 THR B CB  1 
ATOM   4492  O  OG1 . THR B 1 132 ? 19.571  19.287  23.108  1.00 29.83  ? 132 THR B OG1 1 
ATOM   4493  C  CG2 . THR B 1 132 ? 19.035  21.147  24.515  1.00 27.00  ? 132 THR B CG2 1 
ATOM   4494  N  N   . LEU B 1 133 ? 16.815  19.796  26.790  1.00 23.87  ? 133 LEU B N   1 
ATOM   4495  C  CA  . LEU B 1 133 ? 15.776  20.464  27.547  1.00 23.95  ? 133 LEU B CA  1 
ATOM   4496  C  C   . LEU B 1 133 ? 15.482  21.831  26.966  1.00 25.24  ? 133 LEU B C   1 
ATOM   4497  O  O   . LEU B 1 133 ? 16.391  22.547  26.539  1.00 30.59  ? 133 LEU B O   1 
ATOM   4498  C  CB  . LEU B 1 133 ? 16.229  20.611  28.987  1.00 28.93  ? 133 LEU B CB  1 
ATOM   4499  C  CG  . LEU B 1 133 ? 15.135  20.905  29.992  1.00 28.96  ? 133 LEU B CG  1 
ATOM   4500  C  CD1 . LEU B 1 133 ? 14.479  19.581  30.351  1.00 22.22  ? 133 LEU B CD1 1 
ATOM   4501  C  CD2 . LEU B 1 133 ? 15.757  21.557  31.213  1.00 25.49  ? 133 LEU B CD2 1 
ATOM   4502  N  N   . ALA B 1 134 ? 14.212  22.208  26.975  1.00 26.36  ? 134 ALA B N   1 
ATOM   4503  C  CA  . ALA B 1 134 ? 13.869  23.570  26.600  1.00 26.18  ? 134 ALA B CA  1 
ATOM   4504  C  C   . ALA B 1 134 ? 14.555  24.550  27.557  1.00 31.49  ? 134 ALA B C   1 
ATOM   4505  O  O   . ALA B 1 134 ? 14.562  24.328  28.777  1.00 26.95  ? 134 ALA B O   1 
ATOM   4506  C  CB  . ALA B 1 134 ? 12.348  23.764  26.606  1.00 22.88  ? 134 ALA B CB  1 
ATOM   4507  N  N   . PRO B 1 135 ? 15.143  25.634  27.041  1.00 28.59  ? 135 PRO B N   1 
ATOM   4508  C  CA  . PRO B 1 135 ? 16.041  26.473  27.855  1.00 28.26  ? 135 PRO B CA  1 
ATOM   4509  C  C   . PRO B 1 135 ? 15.400  27.029  29.116  1.00 28.70  ? 135 PRO B C   1 
ATOM   4510  O  O   . PRO B 1 135 ? 14.309  27.607  29.090  1.00 31.47  ? 135 PRO B O   1 
ATOM   4511  C  CB  . PRO B 1 135 ? 16.428  27.603  26.892  1.00 28.92  ? 135 PRO B CB  1 
ATOM   4512  C  CG  . PRO B 1 135 ? 16.384  26.984  25.571  1.00 28.39  ? 135 PRO B CG  1 
ATOM   4513  C  CD  . PRO B 1 135 ? 15.231  25.982  25.612  1.00 28.52  ? 135 PRO B CD  1 
ATOM   4514  N  N   . GLU B 1 136 ? 16.107  26.860  30.227  1.00 28.43  ? 136 GLU B N   1 
ATOM   4515  C  CA  . GLU B 1 136 ? 15.760  27.550  31.454  1.00 27.29  ? 136 GLU B CA  1 
ATOM   4516  C  C   . GLU B 1 136 ? 16.432  28.914  31.540  1.00 29.06  ? 136 GLU B C   1 
ATOM   4517  O  O   . GLU B 1 136 ? 15.838  29.844  32.080  1.00 32.95  ? 136 GLU B O   1 
ATOM   4518  C  CB  . GLU B 1 136 ? 16.132  26.682  32.655  1.00 31.50  ? 136 GLU B CB  1 
ATOM   4519  C  CG  . GLU B 1 136 ? 15.225  25.459  32.810  1.00 32.71  ? 136 GLU B CG  1 
ATOM   4520  C  CD  . GLU B 1 136 ? 13.843  25.833  33.309  1.00 34.16  ? 136 GLU B CD  1 
ATOM   4521  O  OE1 . GLU B 1 136 ? 13.707  26.940  33.877  1.00 37.49  ? 136 GLU B OE1 1 
ATOM   4522  O  OE2 . GLU B 1 136 ? 12.897  25.033  33.137  1.00 34.25  ? 136 GLU B OE2 1 
ATOM   4523  N  N   . ALA B 1 137 ? 17.609  29.076  30.934  1.00 35.27  ? 137 ALA B N   1 
ATOM   4524  C  CA  . ALA B 1 137 ? 18.377  30.322  31.013  1.00 29.77  ? 137 ALA B CA  1 
ATOM   4525  C  C   . ALA B 1 137 ? 17.706  31.490  30.289  1.00 26.91  ? 137 ALA B C   1 
ATOM   4526  O  O   . ALA B 1 137 ? 17.032  31.325  29.272  1.00 30.76  ? 137 ALA B O   1 
ATOM   4527  C  CB  . ALA B 1 137 ? 19.766  30.112  30.429  1.00 33.24  ? 137 ALA B CB  1 
ATOM   4528  N  N   . SER B 1 138 ? 17.949  32.697  30.802  1.00 34.37  ? 138 SER B N   1 
ATOM   4529  C  CA  . SER B 1 138 ? 17.243  33.883  30.327  1.00 29.84  ? 138 SER B CA  1 
ATOM   4530  C  C   . SER B 1 138 ? 17.636  34.246  28.901  1.00 29.85  ? 138 SER B C   1 
ATOM   4531  O  O   . SER B 1 138 ? 16.777  34.515  28.058  1.00 31.57  ? 138 SER B O   1 
ATOM   4532  C  CB  . SER B 1 138 ? 17.525  35.053  31.259  1.00 33.37  ? 138 SER B CB  1 
ATOM   4533  O  OG  . SER B 1 138 ? 16.999  36.250  30.735  1.00 37.14  ? 138 SER B OG  1 
ATOM   4534  N  N   . GLY B 1 139 ? 18.930  34.304  28.624  1.00 32.49  ? 139 GLY B N   1 
ATOM   4535  C  CA  . GLY B 1 139 ? 19.411  34.738  27.334  1.00 31.72  ? 139 GLY B CA  1 
ATOM   4536  C  C   . GLY B 1 139 ? 19.369  36.228  27.105  1.00 32.24  ? 139 GLY B C   1 
ATOM   4537  O  O   . GLY B 1 139 ? 19.742  36.675  26.020  1.00 33.17  ? 139 GLY B O   1 
ATOM   4538  N  N   . ALA B 1 140 ? 18.913  37.013  28.075  1.00 31.59  ? 140 ALA B N   1 
ATOM   4539  C  CA  . ALA B 1 140 ? 18.912  38.451  27.893  1.00 29.41  ? 140 ALA B CA  1 
ATOM   4540  C  C   . ALA B 1 140 ? 20.350  38.919  27.680  1.00 33.12  ? 140 ALA B C   1 
ATOM   4541  O  O   . ALA B 1 140 ? 21.294  38.257  28.117  1.00 29.61  ? 140 ALA B O   1 
ATOM   4542  C  CB  . ALA B 1 140 ? 18.285  39.147  29.096  1.00 34.22  ? 140 ALA B CB  1 
ATOM   4543  N  N   . PRO B 1 141 ? 20.550  40.042  26.980  1.00 31.12  ? 141 PRO B N   1 
ATOM   4544  C  CA  . PRO B 1 141 ? 19.539  40.960  26.437  1.00 32.44  ? 141 PRO B CA  1 
ATOM   4545  C  C   . PRO B 1 141 ? 19.053  40.631  25.024  1.00 34.27  ? 141 PRO B C   1 
ATOM   4546  O  O   . PRO B 1 141 ? 18.290  41.400  24.438  1.00 35.33  ? 141 PRO B O   1 
ATOM   4547  C  CB  . PRO B 1 141 ? 20.283  42.283  26.414  1.00 31.43  ? 141 PRO B CB  1 
ATOM   4548  C  CG  . PRO B 1 141 ? 21.685  41.861  26.016  1.00 30.04  ? 141 PRO B CG  1 
ATOM   4549  C  CD  . PRO B 1 141 ? 21.916  40.498  26.670  1.00 30.72  ? 141 PRO B CD  1 
ATOM   4550  N  N   . PHE B 1 142 ? 19.525  39.531  24.457  1.00 34.20  ? 142 PHE B N   1 
ATOM   4551  C  CA  . PHE B 1 142 ? 19.137  39.229  23.090  1.00 32.35  ? 142 PHE B CA  1 
ATOM   4552  C  C   . PHE B 1 142 ? 17.703  38.702  23.040  1.00 36.37  ? 142 PHE B C   1 
ATOM   4553  O  O   . PHE B 1 142 ? 17.121  38.306  24.052  1.00 33.53  ? 142 PHE B O   1 
ATOM   4554  C  CB  . PHE B 1 142 ? 20.085  38.207  22.477  1.00 31.56  ? 142 PHE B CB  1 
ATOM   4555  C  CG  . PHE B 1 142 ? 21.530  38.538  22.668  1.00 32.88  ? 142 PHE B CG  1 
ATOM   4556  C  CD1 . PHE B 1 142 ? 22.069  39.689  22.124  1.00 34.20  ? 142 PHE B CD1 1 
ATOM   4557  C  CD2 . PHE B 1 142 ? 22.343  37.707  23.407  1.00 33.48  ? 142 PHE B CD2 1 
ATOM   4558  C  CE1 . PHE B 1 142 ? 23.393  39.991  22.308  1.00 37.18  ? 142 PHE B CE1 1 
ATOM   4559  C  CE2 . PHE B 1 142 ? 23.664  38.009  23.591  1.00 37.10  ? 142 PHE B CE2 1 
ATOM   4560  C  CZ  . PHE B 1 142 ? 24.188  39.153  23.047  1.00 36.78  ? 142 PHE B CZ  1 
ATOM   4561  N  N   . ARG B 1 143 ? 17.133  38.727  21.839  1.00 38.13  ? 143 ARG B N   1 
ATOM   4562  C  CA  . ARG B 1 143 ? 15.869  38.075  21.535  1.00 37.83  ? 143 ARG B CA  1 
ATOM   4563  C  C   . ARG B 1 143 ? 16.148  36.839  20.685  1.00 33.05  ? 143 ARG B C   1 
ATOM   4564  O  O   . ARG B 1 143 ? 17.172  36.762  20.000  1.00 33.87  ? 143 ARG B O   1 
ATOM   4565  C  CB  . ARG B 1 143 ? 14.921  39.050  20.835  1.00 33.81  ? 143 ARG B CB  1 
ATOM   4566  C  CG  . ARG B 1 143 ? 14.538  40.215  21.760  1.00 37.59  ? 143 ARG B CG  1 
ATOM   4567  C  CD  . ARG B 1 143 ? 13.554  41.186  21.130  1.00 38.48  ? 143 ARG B CD  1 
ATOM   4568  N  NE  . ARG B 1 143 ? 12.177  40.746  21.298  1.00 41.31  ? 143 ARG B NE  1 
ATOM   4569  C  CZ  . ARG B 1 143 ? 11.193  41.032  20.456  1.00 42.52  ? 143 ARG B CZ  1 
ATOM   4570  N  NH1 . ARG B 1 143 ? 11.388  41.812  19.401  1.00 45.22  ? 143 ARG B NH1 1 
ATOM   4571  N  NH2 . ARG B 1 143 ? 9.984   40.523  20.676  1.00 42.57  ? 143 ARG B NH2 1 
ATOM   4572  N  N   . TYR B 1 144 ? 15.255  35.851  20.751  1.00 34.17  ? 144 TYR B N   1 
ATOM   4573  C  CA  . TYR B 1 144 ? 15.549  34.519  20.238  1.00 23.71  ? 144 TYR B CA  1 
ATOM   4574  C  C   . TYR B 1 144 ? 14.545  34.104  19.176  1.00 28.47  ? 144 TYR B C   1 
ATOM   4575  O  O   . TYR B 1 144 ? 13.331  34.247  19.364  1.00 30.70  ? 144 TYR B O   1 
ATOM   4576  C  CB  . TYR B 1 144 ? 15.599  33.520  21.386  1.00 29.36  ? 144 TYR B CB  1 
ATOM   4577  C  CG  . TYR B 1 144 ? 16.827  33.804  22.200  1.00 34.09  ? 144 TYR B CG  1 
ATOM   4578  C  CD1 . TYR B 1 144 ? 18.063  33.279  21.828  1.00 29.30  ? 144 TYR B CD1 1 
ATOM   4579  C  CD2 . TYR B 1 144 ? 16.780  34.678  23.287  1.00 34.03  ? 144 TYR B CD2 1 
ATOM   4580  C  CE1 . TYR B 1 144 ? 19.203  33.576  22.555  1.00 29.65  ? 144 TYR B CE1 1 
ATOM   4581  C  CE2 . TYR B 1 144 ? 17.921  34.977  24.015  1.00 30.87  ? 144 TYR B CE2 1 
ATOM   4582  C  CZ  . TYR B 1 144 ? 19.129  34.428  23.641  1.00 31.00  ? 144 TYR B CZ  1 
ATOM   4583  O  OH  . TYR B 1 144 ? 20.275  34.713  24.351  1.00 30.35  ? 144 TYR B OH  1 
ATOM   4584  N  N   . GLY B 1 145 ? 15.069  33.583  18.061  1.00 23.00  ? 145 GLY B N   1 
ATOM   4585  C  CA  . GLY B 1 145 ? 14.251  33.217  16.928  1.00 21.40  ? 145 GLY B CA  1 
ATOM   4586  C  C   . GLY B 1 145 ? 14.868  32.044  16.202  1.00 26.59  ? 145 GLY B C   1 
ATOM   4587  O  O   . GLY B 1 145 ? 15.976  31.593  16.512  1.00 30.30  ? 145 GLY B O   1 
ATOM   4588  N  N   . VAL B 1 146 ? 14.128  31.555  15.218  1.00 23.98  ? 146 VAL B N   1 
ATOM   4589  C  CA  . VAL B 1 146 ? 14.541  30.422  14.408  1.00 21.81  ? 146 VAL B CA  1 
ATOM   4590  C  C   . VAL B 1 146 ? 14.115  30.720  12.986  1.00 25.80  ? 146 VAL B C   1 
ATOM   4591  O  O   . VAL B 1 146 ? 12.969  31.112  12.755  1.00 26.26  ? 146 VAL B O   1 
ATOM   4592  C  CB  . VAL B 1 146 ? 13.904  29.095  14.872  1.00 22.13  ? 146 VAL B CB  1 
ATOM   4593  C  CG1 . VAL B 1 146 ? 14.361  27.959  13.954  1.00 24.39  ? 146 VAL B CG1 1 
ATOM   4594  C  CG2 . VAL B 1 146 ? 14.274  28.781  16.291  1.00 21.30  ? 146 VAL B CG2 1 
ATOM   4595  N  N   . SER B 1 147 ? 15.017  30.529  12.030  1.00 22.90  ? 147 SER B N   1 
ATOM   4596  C  CA  . SER B 1 147 ? 14.599  30.571  10.645  1.00 24.00  ? 147 SER B CA  1 
ATOM   4597  C  C   . SER B 1 147 ? 14.238  29.175  10.187  1.00 21.67  ? 147 SER B C   1 
ATOM   4598  O  O   . SER B 1 147 ? 14.970  28.228  10.461  1.00 26.12  ? 147 SER B O   1 
ATOM   4599  C  CB  . SER B 1 147 ? 15.689  31.123  9.733   1.00 23.95  ? 147 SER B CB  1 
ATOM   4600  O  OG  . SER B 1 147 ? 15.301  30.848  8.391   1.00 26.53  ? 147 SER B OG  1 
ATOM   4601  N  N   . LEU B 1 148 ? 13.129  29.061  9.452   1.00 20.62  ? 148 LEU B N   1 
ATOM   4602  C  CA  . LEU B 1 148 ? 12.766  27.781  8.838   1.00 20.25  ? 148 LEU B CA  1 
ATOM   4603  C  C   . LEU B 1 148 ? 13.848  27.265  7.896   1.00 21.10  ? 148 LEU B C   1 
ATOM   4604  O  O   . LEU B 1 148 ? 13.797  26.097  7.486   1.00 19.99  ? 148 LEU B O   1 
ATOM   4605  C  CB  . LEU B 1 148 ? 11.427  27.931  8.093   1.00 19.22  ? 148 LEU B CB  1 
ATOM   4606  C  CG  . LEU B 1 148 ? 10.164  28.142  8.931   1.00 17.12  ? 148 LEU B CG  1 
ATOM   4607  C  CD1 . LEU B 1 148 ? 8.916   28.234  8.089   1.00 18.45  ? 148 LEU B CD1 1 
ATOM   4608  C  CD2 . LEU B 1 148 ? 10.053  27.015  9.937   1.00 18.57  ? 148 LEU B CD2 1 
ATOM   4609  N  N   . TYR B 1 149 ? 14.800  28.123  7.501   1.00 23.58  ? 149 TYR B N   1 
ATOM   4610  C  CA  . TYR B 1 149 ? 15.980  27.656  6.779   1.00 21.53  ? 149 TYR B CA  1 
ATOM   4611  C  C   . TYR B 1 149 ? 16.736  26.607  7.571   1.00 20.57  ? 149 TYR B C   1 
ATOM   4612  O  O   . TYR B 1 149 ? 17.384  25.739  6.984   1.00 18.61  ? 149 TYR B O   1 
ATOM   4613  C  CB  . TYR B 1 149 ? 16.923  28.826  6.455   1.00 25.48  ? 149 TYR B CB  1 
ATOM   4614  C  CG  . TYR B 1 149 ? 18.204  28.327  5.837   1.00 23.86  ? 149 TYR B CG  1 
ATOM   4615  C  CD1 . TYR B 1 149 ? 18.189  27.705  4.590   1.00 33.60  ? 149 TYR B CD1 1 
ATOM   4616  C  CD2 . TYR B 1 149 ? 19.414  28.415  6.511   1.00 28.92  ? 149 TYR B CD2 1 
ATOM   4617  C  CE1 . TYR B 1 149 ? 19.343  27.208  4.018   1.00 33.83  ? 149 TYR B CE1 1 
ATOM   4618  C  CE2 . TYR B 1 149 ? 20.584  27.926  5.947   1.00 30.21  ? 149 TYR B CE2 1 
ATOM   4619  C  CZ  . TYR B 1 149 ? 20.541  27.324  4.698   1.00 35.26  ? 149 TYR B CZ  1 
ATOM   4620  O  OH  . TYR B 1 149 ? 21.677  26.824  4.112   1.00 33.68  ? 149 TYR B OH  1 
ATOM   4621  N  N   . SER B 1 150 ? 16.697  26.684  8.906   1.00 22.54  ? 150 SER B N   1 
ATOM   4622  C  CA  . SER B 1 150 ? 17.314  25.647  9.728   1.00 23.69  ? 150 SER B CA  1 
ATOM   4623  C  C   . SER B 1 150 ? 16.759  24.265  9.403   1.00 26.63  ? 150 SER B C   1 
ATOM   4624  O  O   . SER B 1 150 ? 17.466  23.257  9.522   1.00 26.12  ? 150 SER B O   1 
ATOM   4625  C  CB  . SER B 1 150 ? 17.074  25.921  11.215  1.00 21.89  ? 150 SER B CB  1 
ATOM   4626  O  OG  . SER B 1 150 ? 17.552  27.187  11.627  1.00 29.69  ? 150 SER B OG  1 
ATOM   4627  N  N   . TYR B 1 151 ? 15.497  24.193  9.005   1.00 20.54  ? 151 TYR B N   1 
ATOM   4628  C  CA  . TYR B 1 151 ? 14.852  22.908  8.778   1.00 26.27  ? 151 TYR B CA  1 
ATOM   4629  C  C   . TYR B 1 151 ? 14.851  22.501  7.314   1.00 24.40  ? 151 TYR B C   1 
ATOM   4630  O  O   . TYR B 1 151 ? 13.999  21.710  6.902   1.00 20.00  ? 151 TYR B O   1 
ATOM   4631  C  CB  . TYR B 1 151 ? 13.431  22.961  9.309   1.00 22.07  ? 151 TYR B CB  1 
ATOM   4632  C  CG  . TYR B 1 151 ? 13.388  23.259  10.779  1.00 23.13  ? 151 TYR B CG  1 
ATOM   4633  C  CD1 . TYR B 1 151 ? 14.307  22.666  11.640  1.00 23.93  ? 151 TYR B CD1 1 
ATOM   4634  C  CD2 . TYR B 1 151 ? 12.444  24.134  11.311  1.00 19.88  ? 151 TYR B CD2 1 
ATOM   4635  C  CE1 . TYR B 1 151 ? 14.266  22.896  12.985  1.00 24.49  ? 151 TYR B CE1 1 
ATOM   4636  C  CE2 . TYR B 1 151 ? 12.397  24.369  12.674  1.00 25.68  ? 151 TYR B CE2 1 
ATOM   4637  C  CZ  . TYR B 1 151 ? 13.317  23.747  13.496  1.00 23.70  ? 151 TYR B CZ  1 
ATOM   4638  O  OH  . TYR B 1 151 ? 13.311  23.976  14.839  1.00 24.64  ? 151 TYR B OH  1 
ATOM   4639  N  N   . MET B 1 152 ? 15.801  23.012  6.541   1.00 26.87  ? 152 MET B N   1 
ATOM   4640  C  CA  . MET B 1 152 ? 15.822  22.707  5.092   1.00 21.17  ? 152 MET B CA  1 
ATOM   4641  C  C   . MET B 1 152 ? 15.946  21.194  4.863   1.00 28.75  ? 152 MET B C   1 
ATOM   4642  O  O   . MET B 1 152 ? 16.685  20.563  5.631   1.00 27.98  ? 152 MET B O   1 
ATOM   4643  C  CB  . MET B 1 152 ? 16.954  23.450  4.384   1.00 26.42  ? 152 MET B CB  1 
ATOM   4644  C  CG  . MET B 1 152 ? 17.360  22.846  3.061   1.00 27.18  ? 152 MET B CG  1 
ATOM   4645  S  SD  . MET B 1 152 ? 19.000  23.401  2.558   1.00 33.92  ? 152 MET B SD  1 
ATOM   4646  C  CE  . MET B 1 152 ? 19.092  22.682  0.921   1.00 24.39  ? 152 MET B CE  1 
ATOM   4647  N  N   . SER B 1 153 ? 15.250  20.670  3.847   1.00 22.07  ? 153 SER B N   1 
ATOM   4648  C  CA  . SER B 1 153 ? 15.224  19.227  3.504   1.00 27.07  ? 153 SER B CA  1 
ATOM   4649  C  C   . SER B 1 153 ? 14.180  18.534  4.402   1.00 27.72  ? 153 SER B C   1 
ATOM   4650  O  O   . SER B 1 153 ? 13.333  17.835  3.849   1.00 24.87  ? 153 SER B O   1 
ATOM   4651  C  CB  . SER B 1 153 ? 16.599  18.606  3.491   1.00 28.71  ? 153 SER B CB  1 
ATOM   4652  O  OG  . SER B 1 153 ? 17.489  19.350  2.678   1.00 30.75  ? 153 SER B OG  1 
ATOM   4653  N  N   . ASP B 1 154 ? 14.194  18.778  5.715   1.00 25.38  ? 154 ASP B N   1 
ATOM   4654  C  CA  . ASP B 1 154 ? 13.133  18.254  6.616   1.00 26.99  ? 154 ASP B CA  1 
ATOM   4655  C  C   . ASP B 1 154 ? 11.816  18.928  6.229   1.00 26.90  ? 154 ASP B C   1 
ATOM   4656  O  O   . ASP B 1 154 ? 10.797  18.243  6.172   1.00 25.33  ? 154 ASP B O   1 
ATOM   4657  C  CB  . ASP B 1 154 ? 13.451  18.481  8.097   1.00 25.67  ? 154 ASP B CB  1 
ATOM   4658  C  CG  . ASP B 1 154 ? 14.543  17.585  8.649   1.00 28.70  ? 154 ASP B CG  1 
ATOM   4659  O  OD1 . ASP B 1 154 ? 14.654  16.445  8.186   1.00 28.39  ? 154 ASP B OD1 1 
ATOM   4660  O  OD2 . ASP B 1 154 ? 15.266  18.042  9.543   1.00 33.76  ? 154 ASP B OD2 1 
ATOM   4661  N  N   . TYR B 1 155 ? 11.871  20.228  5.948   1.00 27.78  ? 155 TYR B N   1 
ATOM   4662  C  CA  . TYR B 1 155 ? 10.664  20.977  5.536   1.00 24.51  ? 155 TYR B CA  1 
ATOM   4663  C  C   . TYR B 1 155 ? 10.124  20.399  4.231   1.00 23.02  ? 155 TYR B C   1 
ATOM   4664  O  O   . TYR B 1 155 ? 10.833  20.366  3.240   1.00 24.15  ? 155 TYR B O   1 
ATOM   4665  C  CB  . TYR B 1 155 ? 10.912  22.477  5.392   1.00 24.56  ? 155 TYR B CB  1 
ATOM   4666  C  CG  . TYR B 1 155 ? 9.665   23.295  5.604   1.00 27.53  ? 155 TYR B CG  1 
ATOM   4667  C  CD1 . TYR B 1 155 ? 9.251   23.637  6.879   1.00 27.82  ? 155 TYR B CD1 1 
ATOM   4668  C  CD2 . TYR B 1 155 ? 8.875   23.687  4.539   1.00 24.84  ? 155 TYR B CD2 1 
ATOM   4669  C  CE1 . TYR B 1 155 ? 8.096   24.368  7.091   1.00 24.69  ? 155 TYR B CE1 1 
ATOM   4670  C  CE2 . TYR B 1 155 ? 7.718   24.422  4.732   1.00 24.46  ? 155 TYR B CE2 1 
ATOM   4671  C  CZ  . TYR B 1 155 ? 7.328   24.760  6.013   1.00 21.84  ? 155 TYR B CZ  1 
ATOM   4672  O  OH  . TYR B 1 155 ? 6.190   25.485  6.226   1.00 30.51  ? 155 TYR B OH  1 
ATOM   4673  N  N   . GLY B 1 156 ? 8.868   19.986  4.277   1.00 20.11  ? 156 GLY B N   1 
ATOM   4674  C  CA  . GLY B 1 156 ? 8.280   19.399  3.104   1.00 24.66  ? 156 GLY B CA  1 
ATOM   4675  C  C   . GLY B 1 156 ? 8.477   17.901  2.956   1.00 26.72  ? 156 GLY B C   1 
ATOM   4676  O  O   . GLY B 1 156 ? 7.894   17.310  2.034   1.00 23.82  ? 156 GLY B O   1 
ATOM   4677  N  N   . THR B 1 157 ? 9.295   17.269  3.803   1.00 22.04  ? 157 THR B N   1 
ATOM   4678  C  CA  . THR B 1 157 ? 9.469   15.820  3.771   1.00 22.08  ? 157 THR B CA  1 
ATOM   4679  C  C   . THR B 1 157 ? 9.092   15.161  5.083   1.00 24.17  ? 157 THR B C   1 
ATOM   4680  O  O   . THR B 1 157 ? 8.380   14.144  5.075   1.00 23.10  ? 157 THR B O   1 
ATOM   4681  C  CB  . THR B 1 157 ? 10.910  15.409  3.395   1.00 22.14  ? 157 THR B CB  1 
ATOM   4682  O  OG1 . THR B 1 157 ? 11.823  15.859  4.393   1.00 25.09  ? 157 THR B OG1 1 
ATOM   4683  C  CG2 . THR B 1 157 ? 11.302  15.960  2.048   1.00 23.11  ? 157 THR B CG2 1 
ATOM   4684  N  N   . VAL B 1 158 ? 9.538   15.709  6.217   1.00 25.51  ? 158 VAL B N   1 
ATOM   4685  C  CA  . VAL B 1 158 ? 9.145   15.219  7.532   1.00 24.17  ? 158 VAL B CA  1 
ATOM   4686  C  C   . VAL B 1 158 ? 8.506   16.309  8.381   1.00 30.00  ? 158 VAL B C   1 
ATOM   4687  O  O   . VAL B 1 158 ? 8.168   16.069  9.545   1.00 25.50  ? 158 VAL B O   1 
ATOM   4688  C  CB  . VAL B 1 158 ? 10.335  14.579  8.275   1.00 23.37  ? 158 VAL B CB  1 
ATOM   4689  C  CG1 . VAL B 1 158 ? 11.108  13.685  7.339   1.00 19.94  ? 158 VAL B CG1 1 
ATOM   4690  C  CG2 . VAL B 1 158 ? 11.249  15.636  8.903   1.00 21.10  ? 158 VAL B CG2 1 
ATOM   4691  N  N   . MET B 1 159 ? 8.304   17.498  7.814   1.00 18.85  ? 159 MET B N   1 
ATOM   4692  C  CA  . MET B 1 159 ? 7.932   18.639  8.619   1.00 26.06  ? 159 MET B CA  1 
ATOM   4693  C  C   . MET B 1 159 ? 7.010   19.536  7.826   1.00 25.10  ? 159 MET B C   1 
ATOM   4694  O  O   . MET B 1 159 ? 7.230   19.764  6.643   1.00 24.01  ? 159 MET B O   1 
ATOM   4695  C  CB  . MET B 1 159 ? 9.161   19.439  9.043   1.00 30.42  ? 159 MET B CB  1 
ATOM   4696  C  CG  . MET B 1 159 ? 8.923   20.183  10.313  1.00 32.58  ? 159 MET B CG  1 
ATOM   4697  S  SD  . MET B 1 159 ? 10.334  21.192  10.694  1.00 41.28  ? 159 MET B SD  1 
ATOM   4698  C  CE  . MET B 1 159 ? 11.107  20.193  11.942  1.00 27.32  ? 159 MET B CE  1 
ATOM   4699  N  N   . ASP B 1 160 ? 5.978   20.038  8.476   1.00 24.45  ? 160 ASP B N   1 
ATOM   4700  C  CA  . ASP B 1 160 ? 5.176   21.051  7.826   1.00 23.03  ? 160 ASP B CA  1 
ATOM   4701  C  C   . ASP B 1 160 ? 5.251   22.320  8.685   1.00 25.95  ? 160 ASP B C   1 
ATOM   4702  O  O   . ASP B 1 160 ? 5.984   22.383  9.678   1.00 17.68  ? 160 ASP B O   1 
ATOM   4703  C  CB  . ASP B 1 160 ? 3.754   20.541  7.607   1.00 19.03  ? 160 ASP B CB  1 
ATOM   4704  C  CG  . ASP B 1 160 ? 3.101   20.067  8.890   1.00 24.90  ? 160 ASP B CG  1 
ATOM   4705  O  OD1 . ASP B 1 160 ? 3.652   20.302  9.981   1.00 26.44  ? 160 ASP B OD1 1 
ATOM   4706  O  OD2 . ASP B 1 160 ? 2.011   19.469  8.811   1.00 27.64  ? 160 ASP B OD2 1 
ATOM   4707  N  N   . LEU B 1 161 ? 4.469   23.323  8.299   1.00 28.29  ? 161 LEU B N   1 
ATOM   4708  C  CA  . LEU B 1 161 ? 4.574   24.638  8.918   1.00 25.75  ? 161 LEU B CA  1 
ATOM   4709  C  C   . LEU B 1 161 ? 4.249   24.575  10.402  1.00 28.39  ? 161 LEU B C   1 
ATOM   4710  O  O   . LEU B 1 161 ? 4.988   25.117  11.238  1.00 21.74  ? 161 LEU B O   1 
ATOM   4711  C  CB  . LEU B 1 161 ? 3.644   25.615  8.217   1.00 24.77  ? 161 LEU B CB  1 
ATOM   4712  C  CG  . LEU B 1 161 ? 3.490   26.980  8.898   1.00 26.74  ? 161 LEU B CG  1 
ATOM   4713  C  CD1 . LEU B 1 161 ? 4.813   27.672  9.024   1.00 21.38  ? 161 LEU B CD1 1 
ATOM   4714  C  CD2 . LEU B 1 161 ? 2.512   27.813  8.085   1.00 26.56  ? 161 LEU B CD2 1 
ATOM   4715  N  N   . GLU B 1 162 ? 3.140   23.921  10.750  1.00 19.13  ? 162 GLU B N   1 
ATOM   4716  C  CA  . GLU B 1 162 ? 2.727   23.928  12.147  1.00 25.41  ? 162 GLU B CA  1 
ATOM   4717  C  C   . GLU B 1 162 ? 3.703   23.158  13.016  1.00 26.58  ? 162 GLU B C   1 
ATOM   4718  O  O   . GLU B 1 162 ? 3.934   23.525  14.178  1.00 20.60  ? 162 GLU B O   1 
ATOM   4719  C  CB  . GLU B 1 162 ? 1.331   23.349  12.313  1.00 24.92  ? 162 GLU B CB  1 
ATOM   4720  C  CG  . GLU B 1 162 ? 0.858   23.490  13.754  1.00 30.91  ? 162 GLU B CG  1 
ATOM   4721  C  CD  . GLU B 1 162 ? -0.577  23.026  13.959  1.00 31.80  ? 162 GLU B CD  1 
ATOM   4722  O  OE1 . GLU B 1 162 ? -1.144  22.377  13.040  1.00 32.55  ? 162 GLU B OE1 1 
ATOM   4723  O  OE2 . GLU B 1 162 ? -1.120  23.323  15.051  1.00 29.92  ? 162 GLU B OE2 1 
ATOM   4724  N  N   . THR B 1 163 ? 4.242   22.061  12.486  1.00 23.19  ? 163 THR B N   1 
ATOM   4725  C  CA  . THR B 1 163 ? 5.235   21.288  13.215  1.00 22.26  ? 163 THR B CA  1 
ATOM   4726  C  C   . THR B 1 163 ? 6.482   22.129  13.477  1.00 22.65  ? 163 THR B C   1 
ATOM   4727  O  O   . THR B 1 163 ? 7.003   22.164  14.597  1.00 22.74  ? 163 THR B O   1 
ATOM   4728  C  CB  . THR B 1 163 ? 5.568   20.021  12.421  1.00 22.65  ? 163 THR B CB  1 
ATOM   4729  O  OG1 . THR B 1 163 ? 4.362   19.267  12.210  1.00 24.88  ? 163 THR B OG1 1 
ATOM   4730  C  CG2 . THR B 1 163 ? 6.560   19.164  13.151  1.00 24.62  ? 163 THR B CG2 1 
ATOM   4731  N  N   . ALA B 1 164 ? 6.942   22.849  12.458  1.00 24.00  ? 164 ALA B N   1 
ATOM   4732  C  CA  . ALA B 1 164 ? 8.052   23.777  12.620  1.00 25.16  ? 164 ALA B CA  1 
ATOM   4733  C  C   . ALA B 1 164 ? 7.779   24.783  13.740  1.00 21.68  ? 164 ALA B C   1 
ATOM   4734  O  O   . ALA B 1 164 ? 8.599   24.960  14.646  1.00 25.65  ? 164 ALA B O   1 
ATOM   4735  C  CB  . ALA B 1 164 ? 8.292   24.485  11.289  1.00 18.70  ? 164 ALA B CB  1 
ATOM   4736  N  N   . MET B 1 165 ? 6.626   25.452  13.689  1.00 24.17  ? 165 MET B N   1 
ATOM   4737  C  CA  . MET B 1 165 ? 6.304   26.477  14.681  1.00 22.19  ? 165 MET B CA  1 
ATOM   4738  C  C   . MET B 1 165 ? 6.209   25.895  16.085  1.00 22.57  ? 165 MET B C   1 
ATOM   4739  O  O   . MET B 1 165 ? 6.696   26.493  17.049  1.00 24.84  ? 165 MET B O   1 
ATOM   4740  C  CB  . MET B 1 165 ? 4.991   27.160  14.314  1.00 23.85  ? 165 MET B CB  1 
ATOM   4741  C  CG  . MET B 1 165 ? 5.106   28.166  13.189  1.00 24.24  ? 165 MET B CG  1 
ATOM   4742  S  SD  . MET B 1 165 ? 3.582   29.090  13.071  1.00 35.41  ? 165 MET B SD  1 
ATOM   4743  C  CE  . MET B 1 165 ? 3.876   30.280  14.311  1.00 29.67  ? 165 MET B CE  1 
ATOM   4744  N  N   . ALA B 1 166 ? 5.579   24.732  16.228  1.00 23.43  ? 166 ALA B N   1 
ATOM   4745  C  CA  . ALA B 1 166 ? 5.551   24.076  17.533  1.00 23.65  ? 166 ALA B CA  1 
ATOM   4746  C  C   . ALA B 1 166 ? 6.959   23.913  18.096  1.00 19.43  ? 166 ALA B C   1 
ATOM   4747  O  O   . ALA B 1 166 ? 7.195   24.154  19.284  1.00 19.42  ? 166 ALA B O   1 
ATOM   4748  C  CB  . ALA B 1 166 ? 4.848   22.717  17.422  1.00 20.96  ? 166 ALA B CB  1 
ATOM   4749  N  N   . SER B 1 167 ? 7.909   23.501  17.255  1.00 24.67  ? 167 SER B N   1 
ATOM   4750  C  CA  . SER B 1 167 ? 9.274   23.280  17.725  1.00 23.92  ? 167 SER B CA  1 
ATOM   4751  C  C   . SER B 1 167 ? 9.956   24.576  18.128  1.00 23.28  ? 167 SER B C   1 
ATOM   4752  O  O   . SER B 1 167 ? 10.807  24.560  19.018  1.00 23.37  ? 167 SER B O   1 
ATOM   4753  C  CB  . SER B 1 167 ? 10.103  22.598  16.645  1.00 23.53  ? 167 SER B CB  1 
ATOM   4754  O  OG  . SER B 1 167 ? 10.302  23.480  15.550  1.00 25.69  ? 167 SER B OG  1 
ATOM   4755  N  N   . ILE B 1 168 ? 9.632   25.685  17.457  1.00 24.02  ? 168 ILE B N   1 
ATOM   4756  C  CA  . ILE B 1 168 ? 10.236  26.975  17.787  1.00 20.17  ? 168 ILE B CA  1 
ATOM   4757  C  C   . ILE B 1 168 ? 9.664   27.496  19.097  1.00 26.27  ? 168 ILE B C   1 
ATOM   4758  O  O   . ILE B 1 168 ? 10.406  27.918  19.990  1.00 26.59  ? 168 ILE B O   1 
ATOM   4759  C  CB  . ILE B 1 168 ? 10.013  27.988  16.645  1.00 24.37  ? 168 ILE B CB  1 
ATOM   4760  C  CG1 . ILE B 1 168 ? 10.601  27.489  15.330  1.00 20.41  ? 168 ILE B CG1 1 
ATOM   4761  C  CG2 . ILE B 1 168 ? 10.615  29.338  16.989  1.00 15.60  ? 168 ILE B CG2 1 
ATOM   4762  C  CD1 . ILE B 1 168 ? 10.065  28.235  14.126  1.00 20.25  ? 168 ILE B CD1 1 
ATOM   4763  N  N   . ALA B 1 169 ? 8.332   27.430  19.242  1.00 24.66  ? 169 ALA B N   1 
ATOM   4764  C  CA  . ALA B 1 169 ? 7.673   27.832  20.487  1.00 22.94  ? 169 ALA B CA  1 
ATOM   4765  C  C   . ALA B 1 169 ? 8.207   27.065  21.700  1.00 25.54  ? 169 ALA B C   1 
ATOM   4766  O  O   . ALA B 1 169 ? 8.403   27.642  22.775  1.00 24.80  ? 169 ALA B O   1 
ATOM   4767  C  CB  . ALA B 1 169 ? 6.164   27.620  20.359  1.00 25.07  ? 169 ALA B CB  1 
ATOM   4768  N  N   . ASP B 1 170 ? 8.423   25.762  21.554  1.00 22.21  ? 170 ASP B N   1 
ATOM   4769  C  CA  . ASP B 1 170 ? 8.852   24.945  22.685  1.00 26.91  ? 170 ASP B CA  1 
ATOM   4770  C  C   . ASP B 1 170 ? 10.226  25.372  23.176  1.00 31.84  ? 170 ASP B C   1 
ATOM   4771  O  O   . ASP B 1 170 ? 10.518  25.329  24.384  1.00 27.71  ? 170 ASP B O   1 
ATOM   4772  C  CB  . ASP B 1 170 ? 8.891   23.483  22.274  1.00 22.28  ? 170 ASP B CB  1 
ATOM   4773  C  CG  . ASP B 1 170 ? 9.010   22.553  23.456  1.00 31.20  ? 170 ASP B CG  1 
ATOM   4774  O  OD1 . ASP B 1 170 ? 8.070   22.519  24.288  1.00 29.07  ? 170 ASP B OD1 1 
ATOM   4775  O  OD2 . ASP B 1 170 ? 10.042  21.840  23.531  1.00 31.72  ? 170 ASP B OD2 1 
ATOM   4776  N  N   . LEU B 1 171 ? 11.088  25.771  22.241  1.00 30.77  ? 171 LEU B N   1 
ATOM   4777  C  CA  . LEU B 1 171 ? 12.397  26.312  22.555  1.00 28.83  ? 171 LEU B CA  1 
ATOM   4778  C  C   . LEU B 1 171 ? 12.312  27.610  23.347  1.00 27.81  ? 171 LEU B C   1 
ATOM   4779  O  O   . LEU B 1 171 ? 13.333  28.085  23.845  1.00 31.97  ? 171 LEU B O   1 
ATOM   4780  C  CB  . LEU B 1 171 ? 13.159  26.525  21.253  1.00 31.52  ? 171 LEU B CB  1 
ATOM   4781  C  CG  . LEU B 1 171 ? 14.058  25.351  20.931  1.00 31.27  ? 171 LEU B CG  1 
ATOM   4782  C  CD1 . LEU B 1 171 ? 14.692  25.647  19.635  1.00 26.86  ? 171 LEU B CD1 1 
ATOM   4783  C  CD2 . LEU B 1 171 ? 15.110  25.192  22.016  1.00 34.70  ? 171 LEU B CD2 1 
ATOM   4784  N  N   . GLY B 1 172 ? 11.118  28.179  23.501  1.00 33.31  ? 172 GLY B N   1 
ATOM   4785  C  CA  . GLY B 1 172 ? 11.003  29.481  24.109  1.00 25.36  ? 172 GLY B CA  1 
ATOM   4786  C  C   . GLY B 1 172 ? 11.446  30.612  23.211  1.00 29.43  ? 172 GLY B C   1 
ATOM   4787  O  O   . GLY B 1 172 ? 11.646  31.734  23.692  1.00 29.50  ? 172 GLY B O   1 
ATOM   4788  N  N   . ALA B 1 173 ? 11.622  30.352  21.924  1.00 24.95  ? 173 ALA B N   1 
ATOM   4789  C  CA  . ALA B 1 173 ? 11.885  31.428  20.981  1.00 27.19  ? 173 ALA B CA  1 
ATOM   4790  C  C   . ALA B 1 173 ? 10.596  32.176  20.676  1.00 25.68  ? 173 ALA B C   1 
ATOM   4791  O  O   . ALA B 1 173 ? 9.497   31.637  20.773  1.00 25.86  ? 173 ALA B O   1 
ATOM   4792  C  CB  . ALA B 1 173 ? 12.488  30.878  19.684  1.00 27.18  ? 173 ALA B CB  1 
ATOM   4793  N  N   . THR B 1 174 ? 10.730  33.418  20.276  1.00 25.30  ? 174 THR B N   1 
ATOM   4794  C  CA  . THR B 1 174 ? 9.559   34.204  19.961  1.00 23.78  ? 174 THR B CA  1 
ATOM   4795  C  C   . THR B 1 174 ? 9.482   34.629  18.503  1.00 24.53  ? 174 THR B C   1 
ATOM   4796  O  O   . THR B 1 174 ? 8.421   35.095  18.070  1.00 26.63  ? 174 THR B O   1 
ATOM   4797  C  CB  . THR B 1 174 ? 9.509   35.463  20.838  1.00 28.37  ? 174 THR B CB  1 
ATOM   4798  O  OG1 . THR B 1 174 ? 10.673  36.260  20.588  1.00 26.71  ? 174 THR B OG1 1 
ATOM   4799  C  CG2 . THR B 1 174 ? 9.420   35.086  22.307  1.00 29.63  ? 174 THR B CG2 1 
ATOM   4800  N  N   . GLY B 1 175 ? 10.567  34.509  17.744  1.00 28.06  ? 175 GLY B N   1 
ATOM   4801  C  CA  . GLY B 1 175 ? 10.640  35.047  16.396  1.00 25.00  ? 175 GLY B CA  1 
ATOM   4802  C  C   . GLY B 1 175 ? 10.731  33.913  15.386  1.00 20.41  ? 175 GLY B C   1 
ATOM   4803  O  O   . GLY B 1 175 ? 11.478  32.965  15.583  1.00 25.55  ? 175 GLY B O   1 
ATOM   4804  N  N   . ILE B 1 176 ? 9.939   34.014  14.324  1.00 25.66  ? 176 ILE B N   1 
ATOM   4805  C  CA  . ILE B 1 176 ? 10.021  33.066  13.221  1.00 23.15  ? 176 ILE B CA  1 
ATOM   4806  C  C   . ILE B 1 176 ? 10.475  33.825  11.982  1.00 23.11  ? 176 ILE B C   1 
ATOM   4807  O  O   . ILE B 1 176 ? 9.858   34.823  11.591  1.00 26.17  ? 176 ILE B O   1 
ATOM   4808  C  CB  . ILE B 1 176 ? 8.688   32.343  12.994  1.00 26.75  ? 176 ILE B CB  1 
ATOM   4809  C  CG1 . ILE B 1 176 ? 8.766   31.463  11.740  1.00 24.58  ? 176 ILE B CG1 1 
ATOM   4810  C  CG2 . ILE B 1 176 ? 7.528   33.336  12.968  1.00 27.35  ? 176 ILE B CG2 1 
ATOM   4811  C  CD1 . ILE B 1 176 ? 7.778   30.333  11.730  1.00 23.54  ? 176 ILE B CD1 1 
ATOM   4812  N  N   . GLU B 1 177 ? 11.563  33.360  11.380  1.00 25.65  ? 177 GLU B N   1 
ATOM   4813  C  CA  . GLU B 1 177 ? 12.059  33.872  10.111  1.00 22.44  ? 177 GLU B CA  1 
ATOM   4814  C  C   . GLU B 1 177 ? 11.786  32.836  9.028   1.00 22.92  ? 177 GLU B C   1 
ATOM   4815  O  O   . GLU B 1 177 ? 11.937  31.632  9.260   1.00 21.79  ? 177 GLU B O   1 
ATOM   4816  C  CB  . GLU B 1 177 ? 13.560  34.182  10.204  1.00 25.11  ? 177 GLU B CB  1 
ATOM   4817  C  CG  . GLU B 1 177 ? 14.258  34.412  8.875   1.00 30.21  ? 177 GLU B CG  1 
ATOM   4818  C  CD  . GLU B 1 177 ? 15.756  34.581  9.018   1.00 29.04  ? 177 GLU B CD  1 
ATOM   4819  O  OE1 . GLU B 1 177 ? 16.304  34.225  10.088  1.00 31.45  ? 177 GLU B OE1 1 
ATOM   4820  O  OE2 . GLU B 1 177 ? 16.386  35.064  8.055   1.00 30.46  ? 177 GLU B OE2 1 
ATOM   4821  N  N   . ILE B 1 178 ? 11.339  33.290  7.857   1.00 21.26  ? 178 ILE B N   1 
ATOM   4822  C  CA  . ILE B 1 178 ? 11.077  32.379  6.748   1.00 22.85  ? 178 ILE B CA  1 
ATOM   4823  C  C   . ILE B 1 178 ? 11.787  32.886  5.505   1.00 27.89  ? 178 ILE B C   1 
ATOM   4824  O  O   . ILE B 1 178 ? 12.332  33.997  5.473   1.00 26.97  ? 178 ILE B O   1 
ATOM   4825  C  CB  . ILE B 1 178 ? 9.570   32.188  6.460   1.00 24.09  ? 178 ILE B CB  1 
ATOM   4826  C  CG1 . ILE B 1 178 ? 9.017   33.373  5.651   1.00 20.80  ? 178 ILE B CG1 1 
ATOM   4827  C  CG2 . ILE B 1 178 ? 8.787   31.926  7.745   1.00 21.17  ? 178 ILE B CG2 1 
ATOM   4828  C  CD1 . ILE B 1 178 ? 7.544   33.241  5.354   1.00 20.03  ? 178 ILE B CD1 1 
ATOM   4829  N  N   . LEU B 1 179 ? 11.802  32.024  4.480   1.00 27.06  ? 179 LEU B N   1 
ATOM   4830  C  CA  . LEU B 1 179 ? 12.213  32.401  3.140   1.00 27.80  ? 179 LEU B CA  1 
ATOM   4831  C  C   . LEU B 1 179 ? 10.947  32.454  2.297   1.00 25.03  ? 179 LEU B C   1 
ATOM   4832  O  O   . LEU B 1 179 ? 10.207  31.469  2.222   1.00 25.53  ? 179 LEU B O   1 
ATOM   4833  C  CB  . LEU B 1 179 ? 13.238  31.416  2.570   1.00 28.12  ? 179 LEU B CB  1 
ATOM   4834  C  CG  . LEU B 1 179 ? 14.515  31.081  3.364   1.00 27.26  ? 179 LEU B CG  1 
ATOM   4835  C  CD1 . LEU B 1 179 ? 15.353  30.031  2.650   1.00 27.31  ? 179 LEU B CD1 1 
ATOM   4836  C  CD2 . LEU B 1 179 ? 15.360  32.318  3.666   1.00 34.76  ? 179 LEU B CD2 1 
ATOM   4837  N  N   . GLY B 1 180 ? 10.687  33.611  1.692   1.00 24.96  ? 180 GLY B N   1 
ATOM   4838  C  CA  . GLY B 1 180 ? 9.443   33.797  0.958   1.00 22.42  ? 180 GLY B CA  1 
ATOM   4839  C  C   . GLY B 1 180 ? 9.224   32.757  -0.129  1.00 26.12  ? 180 GLY B C   1 
ATOM   4840  O  O   . GLY B 1 180 ? 8.157   32.151  -0.210  1.00 21.99  ? 180 GLY B O   1 
ATOM   4841  N  N   . GLU B 1 181 ? 10.241  32.517  -0.964  1.00 27.09  ? 181 GLU B N   1 
ATOM   4842  C  CA  . GLU B 1 181 ? 10.110  31.567  -2.070  1.00 24.82  ? 181 GLU B CA  1 
ATOM   4843  C  C   . GLU B 1 181 ? 10.261  30.116  -1.640  1.00 24.08  ? 181 GLU B C   1 
ATOM   4844  O  O   . GLU B 1 181 ? 10.260  29.214  -2.498  1.00 26.65  ? 181 GLU B O   1 
ATOM   4845  C  CB  . GLU B 1 181 ? 11.133  31.874  -3.157  1.00 25.68  ? 181 GLU B CB  1 
ATOM   4846  C  CG  . GLU B 1 181 ? 10.889  33.200  -3.838  1.00 29.58  ? 181 GLU B CG  1 
ATOM   4847  C  CD  . GLU B 1 181 ? 11.900  33.468  -4.925  1.00 27.92  ? 181 GLU B CD  1 
ATOM   4848  O  OE1 . GLU B 1 181 ? 12.041  32.610  -5.833  1.00 25.96  ? 181 GLU B OE1 1 
ATOM   4849  O  OE2 . GLU B 1 181 ? 12.581  34.513  -4.828  1.00 27.82  ? 181 GLU B OE2 1 
ATOM   4850  N  N   . ALA B 1 182 ? 10.434  29.870  -0.343  1.00 25.92  ? 182 ALA B N   1 
ATOM   4851  C  CA  . ALA B 1 182 ? 10.494  28.515  0.187   1.00 20.95  ? 182 ALA B CA  1 
ATOM   4852  C  C   . ALA B 1 182 ? 9.178   28.117  0.834   1.00 24.85  ? 182 ALA B C   1 
ATOM   4853  O  O   . ALA B 1 182 ? 8.562   27.128  0.435   1.00 25.86  ? 182 ALA B O   1 
ATOM   4854  C  CB  . ALA B 1 182 ? 11.628  28.379  1.205   1.00 21.51  ? 182 ALA B CB  1 
ATOM   4855  N  N   . HIS B 1 183 ? 8.728   28.904  1.810   1.00 27.88  ? 183 HIS B N   1 
ATOM   4856  C  CA  . HIS B 1 183 ? 7.711   28.496  2.765   1.00 24.77  ? 183 HIS B CA  1 
ATOM   4857  C  C   . HIS B 1 183 ? 6.375   29.184  2.571   1.00 23.46  ? 183 HIS B C   1 
ATOM   4858  O  O   . HIS B 1 183 ? 5.488   28.982  3.403   1.00 25.02  ? 183 HIS B O   1 
ATOM   4859  C  CB  . HIS B 1 183 ? 8.193   28.770  4.193   1.00 24.11  ? 183 HIS B CB  1 
ATOM   4860  C  CG  . HIS B 1 183 ? 9.593   28.317  4.458   1.00 23.55  ? 183 HIS B CG  1 
ATOM   4861  N  ND1 . HIS B 1 183 ? 10.635  29.197  4.632   1.00 19.91  ? 183 HIS B ND1 1 
ATOM   4862  C  CD2 . HIS B 1 183 ? 10.123  27.079  4.575   1.00 20.45  ? 183 HIS B CD2 1 
ATOM   4863  C  CE1 . HIS B 1 183 ? 11.750  28.521  4.841   1.00 23.13  ? 183 HIS B CE1 1 
ATOM   4864  N  NE2 . HIS B 1 183 ? 11.463  27.234  4.826   1.00 22.97  ? 183 HIS B NE2 1 
ATOM   4865  N  N   . VAL B 1 184 ? 6.211   30.021  1.548   1.00 22.83  ? 184 VAL B N   1 
ATOM   4866  C  CA  . VAL B 1 184 ? 4.909   30.594  1.213   1.00 21.50  ? 184 VAL B CA  1 
ATOM   4867  C  C   . VAL B 1 184 ? 4.338   29.772  0.066   1.00 23.41  ? 184 VAL B C   1 
ATOM   4868  O  O   . VAL B 1 184 ? 4.807   29.916  -1.080  1.00 26.09  ? 184 VAL B O   1 
ATOM   4869  C  CB  . VAL B 1 184 ? 4.977   32.072  0.813   1.00 24.21  ? 184 VAL B CB  1 
ATOM   4870  C  CG1 . VAL B 1 184 ? 3.598   32.505  0.308   1.00 20.87  ? 184 VAL B CG1 1 
ATOM   4871  C  CG2 . VAL B 1 184 ? 5.437   32.967  1.972   1.00 29.00  ? 184 VAL B CG2 1 
ATOM   4872  N  N   . PRO B 1 185 ? 3.365   28.912  0.310   1.00 21.25  ? 185 PRO B N   1 
ATOM   4873  C  CA  . PRO B 1 185 ? 2.864   28.068  -0.778  1.00 21.12  ? 185 PRO B CA  1 
ATOM   4874  C  C   . PRO B 1 185 ? 2.116   28.895  -1.813  1.00 25.19  ? 185 PRO B C   1 
ATOM   4875  O  O   . PRO B 1 185 ? 1.455   29.887  -1.503  1.00 21.28  ? 185 PRO B O   1 
ATOM   4876  C  CB  . PRO B 1 185 ? 1.951   27.063  -0.069  1.00 22.27  ? 185 PRO B CB  1 
ATOM   4877  C  CG  . PRO B 1 185 ? 1.688   27.666  1.259   1.00 29.86  ? 185 PRO B CG  1 
ATOM   4878  C  CD  . PRO B 1 185 ? 2.842   28.508  1.622   1.00 23.36  ? 185 PRO B CD  1 
ATOM   4879  N  N   . ASN B 1 186 ? 2.229   28.454  -3.066  1.00 21.59  ? 186 ASN B N   1 
ATOM   4880  C  CA  . ASN B 1 186 ? 1.785   29.215  -4.219  1.00 22.66  ? 186 ASN B CA  1 
ATOM   4881  C  C   . ASN B 1 186 ? 2.428   30.603  -4.280  1.00 23.56  ? 186 ASN B C   1 
ATOM   4882  O  O   . ASN B 1 186 ? 1.788   31.567  -4.699  1.00 28.48  ? 186 ASN B O   1 
ATOM   4883  C  CB  . ASN B 1 186 ? 0.261   29.328  -4.274  1.00 20.97  ? 186 ASN B CB  1 
ATOM   4884  C  CG  . ASN B 1 186 ? -0.233  29.654  -5.683  1.00 29.66  ? 186 ASN B CG  1 
ATOM   4885  O  OD1 . ASN B 1 186 ? 0.176   29.013  -6.658  1.00 28.06  ? 186 ASN B OD1 1 
ATOM   4886  N  ND2 . ASN B 1 186 ? -1.100  30.651  -5.797  1.00 25.44  ? 186 ASN B ND2 1 
ATOM   4887  N  N   . TYR B 1 187 ? 3.696   30.712  -3.880  1.00 24.78  ? 187 TYR B N   1 
ATOM   4888  C  CA  . TYR B 1 187 ? 4.380   32.010  -3.941  1.00 24.54  ? 187 TYR B CA  1 
ATOM   4889  C  C   . TYR B 1 187 ? 4.297   32.552  -5.365  1.00 25.65  ? 187 TYR B C   1 
ATOM   4890  O  O   . TYR B 1 187 ? 4.506   31.799  -6.323  1.00 24.09  ? 187 TYR B O   1 
ATOM   4891  C  CB  . TYR B 1 187 ? 5.850   31.892  -3.518  1.00 24.99  ? 187 TYR B CB  1 
ATOM   4892  C  CG  . TYR B 1 187 ? 6.676   33.147  -3.783  1.00 26.88  ? 187 TYR B CG  1 
ATOM   4893  C  CD1 . TYR B 1 187 ? 7.199   33.415  -5.051  1.00 25.38  ? 187 TYR B CD1 1 
ATOM   4894  C  CD2 . TYR B 1 187 ? 6.936   34.061  -2.768  1.00 23.25  ? 187 TYR B CD2 1 
ATOM   4895  C  CE1 . TYR B 1 187 ? 7.943   34.563  -5.300  1.00 27.19  ? 187 TYR B CE1 1 
ATOM   4896  C  CE2 . TYR B 1 187 ? 7.690   35.215  -3.003  1.00 27.97  ? 187 TYR B CE2 1 
ATOM   4897  C  CZ  . TYR B 1 187 ? 8.192   35.470  -4.276  1.00 29.78  ? 187 TYR B CZ  1 
ATOM   4898  O  OH  . TYR B 1 187 ? 8.943   36.624  -4.525  1.00 22.69  ? 187 TYR B OH  1 
ATOM   4899  N  N   . PRO B 1 188 ? 3.995   33.846  -5.550  1.00 24.00  ? 188 PRO B N   1 
ATOM   4900  C  CA  . PRO B 1 188 ? 3.851   34.904  -4.562  1.00 25.05  ? 188 PRO B CA  1 
ATOM   4901  C  C   . PRO B 1 188 ? 2.401   35.168  -4.235  1.00 28.38  ? 188 PRO B C   1 
ATOM   4902  O  O   . PRO B 1 188 ? 2.098   36.243  -3.745  1.00 24.02  ? 188 PRO B O   1 
ATOM   4903  C  CB  . PRO B 1 188 ? 4.441   36.122  -5.274  1.00 27.30  ? 188 PRO B CB  1 
ATOM   4904  C  CG  . PRO B 1 188 ? 4.138   35.863  -6.770  1.00 29.21  ? 188 PRO B CG  1 
ATOM   4905  C  CD  . PRO B 1 188 ? 3.750   34.372  -6.906  1.00 29.55  ? 188 PRO B CD  1 
ATOM   4906  N  N   . ASN B 1 189 ? 1.506   34.223  -4.520  1.00 24.74  ? 189 ASN B N   1 
ATOM   4907  C  CA  . ASN B 1 189 ? 0.068   34.422  -4.338  1.00 22.92  ? 189 ASN B CA  1 
ATOM   4908  C  C   . ASN B 1 189 ? -0.507  33.429  -3.332  1.00 24.35  ? 189 ASN B C   1 
ATOM   4909  O  O   . ASN B 1 189 ? -1.310  32.556  -3.700  1.00 24.17  ? 189 ASN B O   1 
ATOM   4910  C  CB  . ASN B 1 189 ? -0.668  34.296  -5.671  1.00 31.04  ? 189 ASN B CB  1 
ATOM   4911  C  CG  . ASN B 1 189 ? -0.216  35.328  -6.685  1.00 31.46  ? 189 ASN B CG  1 
ATOM   4912  O  OD1 . ASN B 1 189 ? -0.086  36.508  -6.356  1.00 28.98  ? 189 ASN B OD1 1 
ATOM   4913  N  ND2 . ASN B 1 189 ? 0.002   34.895  -7.926  1.00 23.49  ? 189 ASN B ND2 1 
ATOM   4914  N  N   . PRO B 1 190 ? -0.159  33.558  -2.048  1.00 23.06  ? 190 PRO B N   1 
ATOM   4915  C  CA  . PRO B 1 190 ? -0.759  32.665  -1.051  1.00 25.62  ? 190 PRO B CA  1 
ATOM   4916  C  C   . PRO B 1 190 ? -2.248  32.917  -0.991  1.00 25.32  ? 190 PRO B C   1 
ATOM   4917  O  O   . PRO B 1 190 ? -2.704  34.040  -1.195  1.00 29.17  ? 190 PRO B O   1 
ATOM   4918  C  CB  . PRO B 1 190 ? -0.068  33.059  0.254   1.00 20.94  ? 190 PRO B CB  1 
ATOM   4919  C  CG  . PRO B 1 190 ? 0.236   34.526  0.068   1.00 26.76  ? 190 PRO B CG  1 
ATOM   4920  C  CD  . PRO B 1 190 ? 0.653   34.609  -1.411  1.00 24.78  ? 190 PRO B CD  1 
ATOM   4921  N  N   . SER B 1 191 ? -3.002  31.842  -0.756  1.00 23.41  ? 191 SER B N   1 
ATOM   4922  C  CA  . SER B 1 191 ? -4.450  31.913  -0.667  1.00 24.56  ? 191 SER B CA  1 
ATOM   4923  C  C   . SER B 1 191 ? -4.869  32.604  0.627   1.00 25.19  ? 191 SER B C   1 
ATOM   4924  O  O   . SER B 1 191 ? -4.145  32.582  1.623   1.00 29.14  ? 191 SER B O   1 
ATOM   4925  C  CB  . SER B 1 191 ? -5.049  30.510  -0.736  1.00 23.28  ? 191 SER B CB  1 
ATOM   4926  O  OG  . SER B 1 191 ? -4.684  29.741  0.395   1.00 26.85  ? 191 SER B OG  1 
ATOM   4927  N  N   . ASP B 1 192 ? -6.042  33.252  0.596   1.00 24.89  ? 192 ASP B N   1 
ATOM   4928  C  CA  . ASP B 1 192 ? -6.586  33.835  1.820   1.00 25.97  ? 192 ASP B CA  1 
ATOM   4929  C  C   . ASP B 1 192 ? -6.719  32.789  2.925   1.00 28.30  ? 192 ASP B C   1 
ATOM   4930  O  O   . ASP B 1 192 ? -6.565  33.109  4.110   1.00 27.72  ? 192 ASP B O   1 
ATOM   4931  C  CB  . ASP B 1 192 ? -7.956  34.468  1.567   1.00 31.49  ? 192 ASP B CB  1 
ATOM   4932  C  CG  . ASP B 1 192 ? -7.898  35.691  0.691   1.00 27.73  ? 192 ASP B CG  1 
ATOM   4933  O  OD1 . ASP B 1 192 ? -6.802  36.196  0.425   1.00 29.39  ? 192 ASP B OD1 1 
ATOM   4934  O  OD2 . ASP B 1 192 ? -8.968  36.161  0.280   1.00 32.82  ? 192 ASP B OD2 1 
ATOM   4935  N  N   . GLU B 1 193 ? -7.014  31.536  2.564   1.00 28.02  ? 193 GLU B N   1 
ATOM   4936  C  CA  . GLU B 1 193 ? -7.105  30.491  3.579   1.00 28.99  ? 193 GLU B CA  1 
ATOM   4937  C  C   . GLU B 1 193 ? -5.744  30.217  4.209   1.00 29.99  ? 193 GLU B C   1 
ATOM   4938  O  O   . GLU B 1 193 ? -5.635  30.100  5.436   1.00 28.82  ? 193 GLU B O   1 
ATOM   4939  C  CB  . GLU B 1 193 ? -7.700  29.217  2.975   1.00 37.31  ? 193 GLU B CB  1 
ATOM   4940  C  CG  . GLU B 1 193 ? -7.262  27.917  3.666   1.00 41.98  ? 193 GLU B CG  1 
ATOM   4941  C  CD  . GLU B 1 193 ? -8.021  26.684  3.185   1.00 45.14  ? 193 GLU B CD  1 
ATOM   4942  O  OE1 . GLU B 1 193 ? -8.100  26.444  1.959   1.00 46.31  ? 193 GLU B OE1 1 
ATOM   4943  O  OE2 . GLU B 1 193 ? -8.537  25.944  4.048   1.00 54.73  ? 193 GLU B OE2 1 
ATOM   4944  N  N   . TRP B 1 194 ? -4.688  30.140  3.399   1.00 29.09  ? 194 TRP B N   1 
ATOM   4945  C  CA  . TRP B 1 194 ? -3.361  29.947  3.974   1.00 25.95  ? 194 TRP B CA  1 
ATOM   4946  C  C   . TRP B 1 194 ? -2.938  31.137  4.821   1.00 27.23  ? 194 TRP B C   1 
ATOM   4947  O  O   . TRP B 1 194 ? -2.302  30.957  5.865   1.00 22.80  ? 194 TRP B O   1 
ATOM   4948  C  CB  . TRP B 1 194 ? -2.316  29.694  2.900   1.00 28.90  ? 194 TRP B CB  1 
ATOM   4949  C  CG  . TRP B 1 194 ? -0.954  29.395  3.494   1.00 27.17  ? 194 TRP B CG  1 
ATOM   4950  C  CD1 . TRP B 1 194 ? -0.460  28.171  3.823   1.00 27.22  ? 194 TRP B CD1 1 
ATOM   4951  C  CD2 . TRP B 1 194 ? 0.070   30.343  3.833   1.00 28.41  ? 194 TRP B CD2 1 
ATOM   4952  N  NE1 . TRP B 1 194 ? 0.795   28.291  4.356   1.00 26.21  ? 194 TRP B NE1 1 
ATOM   4953  C  CE2 . TRP B 1 194 ? 1.149   29.616  4.366   1.00 27.35  ? 194 TRP B CE2 1 
ATOM   4954  C  CE3 . TRP B 1 194 ? 0.179   31.738  3.736   1.00 31.11  ? 194 TRP B CE3 1 
ATOM   4955  C  CZ2 . TRP B 1 194 ? 2.333   30.231  4.787   1.00 26.90  ? 194 TRP B CZ2 1 
ATOM   4956  C  CZ3 . TRP B 1 194 ? 1.356   32.348  4.177   1.00 27.18  ? 194 TRP B CZ3 1 
ATOM   4957  C  CH2 . TRP B 1 194 ? 2.415   31.589  4.686   1.00 23.05  ? 194 TRP B CH2 1 
ATOM   4958  N  N   . VAL B 1 195 ? -3.246  32.364  4.382   1.00 26.62  ? 195 VAL B N   1 
ATOM   4959  C  CA  . VAL B 1 195 ? -2.798  33.521  5.156   1.00 27.86  ? 195 VAL B CA  1 
ATOM   4960  C  C   . VAL B 1 195 ? -3.527  33.576  6.497   1.00 24.60  ? 195 VAL B C   1 
ATOM   4961  O  O   . VAL B 1 195 ? -2.912  33.801  7.541   1.00 26.82  ? 195 VAL B O   1 
ATOM   4962  C  CB  . VAL B 1 195 ? -2.961  34.834  4.367   1.00 27.59  ? 195 VAL B CB  1 
ATOM   4963  C  CG1 . VAL B 1 195 ? -2.698  36.028  5.294   1.00 24.38  ? 195 VAL B CG1 1 
ATOM   4964  C  CG2 . VAL B 1 195 ? -2.009  34.874  3.155   1.00 22.21  ? 195 VAL B CG2 1 
ATOM   4965  N  N   . GLU B 1 196 ? -4.837  33.338  6.493   1.00 26.58  ? 196 GLU B N   1 
ATOM   4966  C  CA  . GLU B 1 196 ? -5.578  33.251  7.749   1.00 27.14  ? 196 GLU B CA  1 
ATOM   4967  C  C   . GLU B 1 196 ? -4.999  32.184  8.676   1.00 27.80  ? 196 GLU B C   1 
ATOM   4968  O  O   . GLU B 1 196 ? -4.902  32.393  9.894   1.00 27.99  ? 196 GLU B O   1 
ATOM   4969  C  CB  . GLU B 1 196 ? -7.054  32.966  7.460   1.00 32.60  ? 196 GLU B CB  1 
ATOM   4970  C  CG  . GLU B 1 196 ? -8.063  33.788  8.272   1.00 41.96  ? 196 GLU B CG  1 
ATOM   4971  C  CD  . GLU B 1 196 ? -9.510  33.375  7.980   1.00 53.61  ? 196 GLU B CD  1 
ATOM   4972  O  OE1 . GLU B 1 196 ? -9.770  32.156  7.820   1.00 45.73  ? 196 GLU B OE1 1 
ATOM   4973  O  OE2 . GLU B 1 196 ? -10.375 34.276  7.857   1.00 59.68  ? 196 GLU B OE2 1 
ATOM   4974  N  N   . GLN B 1 197 ? -4.628  31.026  8.133   1.00 24.27  ? 197 GLN B N   1 
ATOM   4975  C  CA  . GLN B 1 197 ? -4.113  29.970  8.998   1.00 25.42  ? 197 GLN B CA  1 
ATOM   4976  C  C   . GLN B 1 197 ? -2.722  30.310  9.514   1.00 27.37  ? 197 GLN B C   1 
ATOM   4977  O  O   . GLN B 1 197 ? -2.359  29.932  10.631  1.00 28.49  ? 197 GLN B O   1 
ATOM   4978  C  CB  . GLN B 1 197 ? -4.107  28.636  8.253   1.00 28.03  ? 197 GLN B CB  1 
ATOM   4979  C  CG  . GLN B 1 197 ? -3.543  27.473  9.067   1.00 33.26  ? 197 GLN B CG  1 
ATOM   4980  C  CD  . GLN B 1 197 ? -4.279  27.202  10.387  1.00 32.16  ? 197 GLN B CD  1 
ATOM   4981  O  OE1 . GLN B 1 197 ? -5.396  27.692  10.632  1.00 40.07  ? 197 GLN B OE1 1 
ATOM   4982  N  NE2 . GLN B 1 197 ? -3.647  26.407  11.241  1.00 32.69  ? 197 GLN B NE2 1 
ATOM   4983  N  N   . TRP B 1 198 ? -1.942  31.016  8.708   1.00 24.40  ? 198 TRP B N   1 
ATOM   4984  C  CA  . TRP B 1 198 ? -0.654  31.533  9.140   1.00 25.16  ? 198 TRP B CA  1 
ATOM   4985  C  C   . TRP B 1 198 ? -0.808  32.376  10.397  1.00 23.23  ? 198 TRP B C   1 
ATOM   4986  O  O   . TRP B 1 198 ? -0.130  32.141  11.403  1.00 22.85  ? 198 TRP B O   1 
ATOM   4987  C  CB  . TRP B 1 198 ? -0.050  32.339  7.988   1.00 25.29  ? 198 TRP B CB  1 
ATOM   4988  C  CG  . TRP B 1 198 ? 1.044   33.287  8.334   1.00 27.06  ? 198 TRP B CG  1 
ATOM   4989  C  CD1 . TRP B 1 198 ? 0.947   34.647  8.472   1.00 26.27  ? 198 TRP B CD1 1 
ATOM   4990  C  CD2 . TRP B 1 198 ? 2.417   32.957  8.547   1.00 23.97  ? 198 TRP B CD2 1 
ATOM   4991  N  NE1 . TRP B 1 198 ? 2.182   35.179  8.759   1.00 23.73  ? 198 TRP B NE1 1 
ATOM   4992  C  CE2 . TRP B 1 198 ? 3.098   34.158  8.823   1.00 25.68  ? 198 TRP B CE2 1 
ATOM   4993  C  CE3 . TRP B 1 198 ? 3.133   31.762  8.545   1.00 19.61  ? 198 TRP B CE3 1 
ATOM   4994  C  CZ2 . TRP B 1 198 ? 4.467   34.190  9.092   1.00 27.33  ? 198 TRP B CZ2 1 
ATOM   4995  C  CZ3 . TRP B 1 198 ? 4.478   31.797  8.822   1.00 22.82  ? 198 TRP B CZ3 1 
ATOM   4996  C  CH2 . TRP B 1 198 ? 5.135   32.999  9.091   1.00 27.13  ? 198 TRP B CH2 1 
ATOM   4997  N  N   . PHE B 1 199 ? -1.727  33.343  10.366  1.00 26.68  ? 199 PHE B N   1 
ATOM   4998  C  CA  . PHE B 1 199 ? -1.930  34.201  11.529  1.00 27.58  ? 199 PHE B CA  1 
ATOM   4999  C  C   . PHE B 1 199 ? -2.559  33.443  12.688  1.00 30.87  ? 199 PHE B C   1 
ATOM   5000  O  O   . PHE B 1 199 ? -2.280  33.755  13.855  1.00 28.22  ? 199 PHE B O   1 
ATOM   5001  C  CB  . PHE B 1 199 ? -2.787  35.406  11.150  1.00 24.17  ? 199 PHE B CB  1 
ATOM   5002  C  CG  . PHE B 1 199 ? -2.027  36.460  10.403  1.00 27.32  ? 199 PHE B CG  1 
ATOM   5003  C  CD1 . PHE B 1 199 ? -1.001  37.158  11.026  1.00 27.02  ? 199 PHE B CD1 1 
ATOM   5004  C  CD2 . PHE B 1 199 ? -2.303  36.724  9.071   1.00 25.41  ? 199 PHE B CD2 1 
ATOM   5005  C  CE1 . PHE B 1 199 ? -0.274  38.132  10.339  1.00 25.11  ? 199 PHE B CE1 1 
ATOM   5006  C  CE2 . PHE B 1 199 ? -1.590  37.676  8.379   1.00 23.65  ? 199 PHE B CE2 1 
ATOM   5007  C  CZ  . PHE B 1 199 ? -0.570  38.390  9.017   1.00 32.67  ? 199 PHE B CZ  1 
ATOM   5008  N  N   . ALA B 1 200 ? -3.423  32.465  12.404  1.00 27.00  ? 200 ALA B N   1 
ATOM   5009  C  CA  . ALA B 1 200 ? -3.892  31.597  13.479  1.00 29.99  ? 200 ALA B CA  1 
ATOM   5010  C  C   . ALA B 1 200 ? -2.712  30.905  14.151  1.00 28.95  ? 200 ALA B C   1 
ATOM   5011  O  O   . ALA B 1 200 ? -2.552  30.969  15.377  1.00 29.17  ? 200 ALA B O   1 
ATOM   5012  C  CB  . ALA B 1 200 ? -4.905  30.584  12.941  1.00 28.14  ? 200 ALA B CB  1 
ATOM   5013  N  N   . LEU B 1 201 ? -1.829  30.312  13.347  1.00 24.15  ? 201 LEU B N   1 
ATOM   5014  C  CA  . LEU B 1 201 ? -0.716  29.544  13.891  1.00 24.15  ? 201 LEU B CA  1 
ATOM   5015  C  C   . LEU B 1 201 ? 0.182   30.405  14.772  1.00 25.46  ? 201 LEU B C   1 
ATOM   5016  O  O   . LEU B 1 201 ? 0.576   29.989  15.865  1.00 25.87  ? 201 LEU B O   1 
ATOM   5017  C  CB  . LEU B 1 201 ? 0.091   28.917  12.756  1.00 23.16  ? 201 LEU B CB  1 
ATOM   5018  C  CG  . LEU B 1 201 ? -0.572  27.771  11.984  1.00 27.43  ? 201 LEU B CG  1 
ATOM   5019  C  CD1 . LEU B 1 201 ? 0.324   27.326  10.848  1.00 23.07  ? 201 LEU B CD1 1 
ATOM   5020  C  CD2 . LEU B 1 201 ? -0.867  26.610  12.929  1.00 28.50  ? 201 LEU B CD2 1 
ATOM   5021  N  N   . LEU B 1 202 ? 0.551   31.590  14.291  1.00 22.52  ? 202 LEU B N   1 
ATOM   5022  C  CA  . LEU B 1 202 ? 1.437   32.469  15.041  1.00 24.90  ? 202 LEU B CA  1 
ATOM   5023  C  C   . LEU B 1 202 ? 0.839   32.821  16.396  1.00 27.32  ? 202 LEU B C   1 
ATOM   5024  O  O   . LEU B 1 202 ? 1.528   32.810  17.425  1.00 31.24  ? 202 LEU B O   1 
ATOM   5025  C  CB  . LEU B 1 202 ? 1.708   33.743  14.229  1.00 28.61  ? 202 LEU B CB  1 
ATOM   5026  C  CG  . LEU B 1 202 ? 2.563   33.681  12.970  1.00 25.60  ? 202 LEU B CG  1 
ATOM   5027  C  CD1 . LEU B 1 202 ? 2.295   34.925  12.100  1.00 24.69  ? 202 LEU B CD1 1 
ATOM   5028  C  CD2 . LEU B 1 202 ? 4.021   33.617  13.364  1.00 28.18  ? 202 LEU B CD2 1 
ATOM   5029  N  N   . SER B 1 203 ? -0.442  33.174  16.408  1.00 31.91  ? 203 SER B N   1 
ATOM   5030  C  CA  . SER B 1 203 ? -1.125  33.421  17.669  1.00 27.15  ? 203 SER B CA  1 
ATOM   5031  C  C   . SER B 1 203 ? -1.063  32.191  18.557  1.00 30.29  ? 203 SER B C   1 
ATOM   5032  O  O   . SER B 1 203 ? -0.702  32.283  19.733  1.00 27.85  ? 203 SER B O   1 
ATOM   5033  C  CB  . SER B 1 203 ? -2.575  33.842  17.413  1.00 28.74  ? 203 SER B CB  1 
ATOM   5034  O  OG  . SER B 1 203 ? -3.212  34.170  18.644  1.00 34.59  ? 203 SER B OG  1 
ATOM   5035  N  N   . THR B 1 204 ? -1.408  31.025  18.006  1.00 27.16  ? 204 THR B N   1 
ATOM   5036  C  CA  . THR B 1 204 ? -1.411  29.805  18.804  1.00 27.51  ? 204 THR B CA  1 
ATOM   5037  C  C   . THR B 1 204 ? -0.044  29.565  19.430  1.00 27.73  ? 204 THR B C   1 
ATOM   5038  O  O   . THR B 1 204 ? 0.069   29.350  20.638  1.00 28.73  ? 204 THR B O   1 
ATOM   5039  C  CB  . THR B 1 204 ? -1.844  28.623  17.934  1.00 27.26  ? 204 THR B CB  1 
ATOM   5040  O  OG1 . THR B 1 204 ? -3.225  28.786  17.569  1.00 25.60  ? 204 THR B OG1 1 
ATOM   5041  C  CG2 . THR B 1 204 ? -1.653  27.314  18.650  1.00 24.82  ? 204 THR B CG2 1 
ATOM   5042  N  N   . TYR B 1 205 ? 1.016   29.675  18.641  1.00 27.46  ? 205 TYR B N   1 
ATOM   5043  C  CA  . TYR B 1 205 ? 2.348   29.373  19.137  1.00 26.41  ? 205 TYR B CA  1 
ATOM   5044  C  C   . TYR B 1 205 ? 3.099   30.588  19.674  1.00 24.02  ? 205 TYR B C   1 
ATOM   5045  O  O   . TYR B 1 205 ? 4.261   30.448  20.061  1.00 26.98  ? 205 TYR B O   1 
ATOM   5046  C  CB  . TYR B 1 205 ? 3.151   28.668  18.045  1.00 25.83  ? 205 TYR B CB  1 
ATOM   5047  C  CG  . TYR B 1 205 ? 2.526   27.335  17.775  1.00 23.65  ? 205 TYR B CG  1 
ATOM   5048  C  CD1 . TYR B 1 205 ? 2.720   26.278  18.654  1.00 25.72  ? 205 TYR B CD1 1 
ATOM   5049  C  CD2 . TYR B 1 205 ? 1.645   27.160  16.719  1.00 25.89  ? 205 TYR B CD2 1 
ATOM   5050  C  CE1 . TYR B 1 205 ? 2.119   25.063  18.458  1.00 26.90  ? 205 TYR B CE1 1 
ATOM   5051  C  CE2 . TYR B 1 205 ? 1.043   25.934  16.501  1.00 25.81  ? 205 TYR B CE2 1 
ATOM   5052  C  CZ  . TYR B 1 205 ? 1.283   24.886  17.383  1.00 26.11  ? 205 TYR B CZ  1 
ATOM   5053  O  OH  . TYR B 1 205 ? 0.676   23.672  17.191  1.00 23.49  ? 205 TYR B OH  1 
ATOM   5054  N  N   . GLY B 1 206 ? 2.459   31.748  19.760  1.00 26.65  ? 206 GLY B N   1 
ATOM   5055  C  CA  . GLY B 1 206 ? 3.088   32.875  20.424  1.00 30.00  ? 206 GLY B CA  1 
ATOM   5056  C  C   . GLY B 1 206 ? 4.302   33.405  19.703  1.00 29.55  ? 206 GLY B C   1 
ATOM   5057  O  O   . GLY B 1 206 ? 5.205   33.962  20.343  1.00 29.33  ? 206 GLY B O   1 
ATOM   5058  N  N   . LEU B 1 207 ? 4.353   33.251  18.384  1.00 27.21  ? 207 LEU B N   1 
ATOM   5059  C  CA  . LEU B 1 207 ? 5.514   33.673  17.618  1.00 27.70  ? 207 LEU B CA  1 
ATOM   5060  C  C   . LEU B 1 207 ? 5.235   34.973  16.866  1.00 26.07  ? 207 LEU B C   1 
ATOM   5061  O  O   . LEU B 1 207 ? 4.089   35.315  16.571  1.00 25.63  ? 207 LEU B O   1 
ATOM   5062  C  CB  . LEU B 1 207 ? 5.946   32.566  16.641  1.00 26.64  ? 207 LEU B CB  1 
ATOM   5063  C  CG  . LEU B 1 207 ? 6.432   31.266  17.301  1.00 29.66  ? 207 LEU B CG  1 
ATOM   5064  C  CD1 . LEU B 1 207 ? 6.765   30.198  16.258  1.00 26.80  ? 207 LEU B CD1 1 
ATOM   5065  C  CD2 . LEU B 1 207 ? 7.641   31.551  18.221  1.00 25.20  ? 207 LEU B CD2 1 
ATOM   5066  N  N   . GLU B 1 208 ? 6.319   35.694  16.536  1.00 26.66  ? 208 GLU B N   1 
ATOM   5067  C  CA  . GLU B 1 208 ? 6.167   36.913  15.754  1.00 26.77  ? 208 GLU B CA  1 
ATOM   5068  C  C   . GLU B 1 208 ? 7.031   36.849  14.496  1.00 20.75  ? 208 GLU B C   1 
ATOM   5069  O  O   . GLU B 1 208 ? 8.168   36.378  14.547  1.00 25.80  ? 208 GLU B O   1 
ATOM   5070  C  CB  . GLU B 1 208 ? 6.540   38.150  16.587  1.00 30.06  ? 208 GLU B CB  1 
ATOM   5071  C  CG  . GLU B 1 208 ? 8.020   38.514  16.474  1.00 41.69  ? 208 GLU B CG  1 
ATOM   5072  C  CD  . GLU B 1 208 ? 8.462   39.608  17.423  1.00 44.46  ? 208 GLU B CD  1 
ATOM   5073  O  OE1 . GLU B 1 208 ? 8.405   39.376  18.653  1.00 45.63  ? 208 GLU B OE1 1 
ATOM   5074  O  OE2 . GLU B 1 208 ? 8.885   40.680  16.927  1.00 48.76  ? 208 GLU B OE2 1 
ATOM   5075  N  N   . PRO B 1 209 ? 6.512   37.268  13.349  1.00 24.98  ? 209 PRO B N   1 
ATOM   5076  C  CA  . PRO B 1 209 ? 7.336   37.268  12.132  1.00 26.94  ? 209 PRO B CA  1 
ATOM   5077  C  C   . PRO B 1 209 ? 8.469   38.278  12.240  1.00 25.74  ? 209 PRO B C   1 
ATOM   5078  O  O   . PRO B 1 209 ? 8.244   39.442  12.573  1.00 35.71  ? 209 PRO B O   1 
ATOM   5079  C  CB  . PRO B 1 209 ? 6.344   37.652  11.028  1.00 28.76  ? 209 PRO B CB  1 
ATOM   5080  C  CG  . PRO B 1 209 ? 5.020   37.196  11.572  1.00 26.84  ? 209 PRO B CG  1 
ATOM   5081  C  CD  . PRO B 1 209 ? 5.088   37.466  13.052  1.00 25.49  ? 209 PRO B CD  1 
ATOM   5082  N  N   . THR B 1 210 ? 9.693   37.824  11.933  1.00 27.14  ? 210 THR B N   1 
ATOM   5083  C  CA  . THR B 1 210 ? 10.867  38.682  11.994  1.00 28.86  ? 210 THR B CA  1 
ATOM   5084  C  C   . THR B 1 210 ? 11.363  38.956  10.582  1.00 26.93  ? 210 THR B C   1 
ATOM   5085  O  O   . THR B 1 210 ? 10.965  39.958  9.975   1.00 29.31  ? 210 THR B O   1 
ATOM   5086  C  CB  . THR B 1 210 ? 11.953  38.060  12.880  1.00 25.02  ? 210 THR B CB  1 
ATOM   5087  O  OG1 . THR B 1 210 ? 12.400  36.842  12.302  1.00 23.99  ? 210 THR B OG1 1 
ATOM   5088  C  CG2 . THR B 1 210 ? 11.430  37.783  14.260  1.00 25.82  ? 210 THR B CG2 1 
ATOM   5089  N  N   . ASN B 1 211 ? 12.208  38.103  10.009  1.00 32.45  ? 211 ASN B N   1 
ATOM   5090  C  CA  . ASN B 1 211 ? 12.803  38.317  8.696   1.00 27.19  ? 211 ASN B CA  1 
ATOM   5091  C  C   . ASN B 1 211 ? 12.154  37.420  7.646   1.00 28.43  ? 211 ASN B C   1 
ATOM   5092  O  O   . ASN B 1 211 ? 11.934  36.217  7.872   1.00 25.07  ? 211 ASN B O   1 
ATOM   5093  C  CB  . ASN B 1 211 ? 14.312  38.059  8.754   1.00 29.45  ? 211 ASN B CB  1 
ATOM   5094  C  CG  . ASN B 1 211 ? 15.014  38.299  7.421   1.00 32.39  ? 211 ASN B CG  1 
ATOM   5095  O  OD1 . ASN B 1 211 ? 14.709  39.259  6.708   1.00 34.43  ? 211 ASN B OD1 1 
ATOM   5096  N  ND2 . ASN B 1 211 ? 16.002  37.465  7.114   1.00 26.90  ? 211 ASN B ND2 1 
ATOM   5097  N  N   . MET B 1 212 ? 11.834  38.009  6.504   1.00 21.90  ? 212 MET B N   1 
ATOM   5098  C  CA  . MET B 1 212 ? 11.481  37.245  5.321   1.00 29.51  ? 212 MET B CA  1 
ATOM   5099  C  C   . MET B 1 212 ? 12.648  37.297  4.353   1.00 30.90  ? 212 MET B C   1 
ATOM   5100  O  O   . MET B 1 212 ? 13.035  38.380  3.893   1.00 37.38  ? 212 MET B O   1 
ATOM   5101  C  CB  . MET B 1 212 ? 10.208  37.754  4.655   1.00 29.73  ? 212 MET B CB  1 
ATOM   5102  C  CG  . MET B 1 212 ? 9.680   36.717  3.667   1.00 28.02  ? 212 MET B CG  1 
ATOM   5103  S  SD  . MET B 1 212 ? 8.291   37.238  2.669   1.00 29.33  ? 212 MET B SD  1 
ATOM   5104  C  CE  . MET B 1 212 ? 9.123   38.152  1.353   1.00 22.48  ? 212 MET B CE  1 
ATOM   5105  N  N   . GLY B 1 213 ? 13.221  36.134  4.073   1.00 23.85  ? 213 GLY B N   1 
ATOM   5106  C  CA  . GLY B 1 213 ? 14.254  36.046  3.056   1.00 27.56  ? 213 GLY B CA  1 
ATOM   5107  C  C   . GLY B 1 213 ? 13.674  36.280  1.670   1.00 29.77  ? 213 GLY B C   1 
ATOM   5108  O  O   . GLY B 1 213 ? 12.557  35.861  1.355   1.00 28.58  ? 213 GLY B O   1 
ATOM   5109  N  N   . SER B 1 214 ? 14.458  36.948  0.829   1.00 27.66  ? 214 SER B N   1 
ATOM   5110  C  CA  . SER B 1 214 ? 14.001  37.400  -0.473  1.00 29.74  ? 214 SER B CA  1 
ATOM   5111  C  C   . SER B 1 214 ? 15.187  37.358  -1.429  1.00 28.70  ? 214 SER B C   1 
ATOM   5112  O  O   . SER B 1 214 ? 16.339  37.274  -0.999  1.00 29.84  ? 214 SER B O   1 
ATOM   5113  C  CB  . SER B 1 214 ? 13.376  38.793  -0.327  1.00 27.33  ? 214 SER B CB  1 
ATOM   5114  O  OG  . SER B 1 214 ? 13.497  39.571  -1.471  1.00 33.33  ? 214 SER B OG  1 
ATOM   5115  N  N   . TRP B 1 215 ? 14.908  37.374  -2.737  1.00 29.95  ? 215 TRP B N   1 
ATOM   5116  C  CA  . TRP B 1 215 ? 15.973  37.299  -3.736  1.00 29.10  ? 215 TRP B CA  1 
ATOM   5117  C  C   . TRP B 1 215 ? 15.752  38.274  -4.883  1.00 28.47  ? 215 TRP B C   1 
ATOM   5118  O  O   . TRP B 1 215 ? 14.618  38.589  -5.276  1.00 28.90  ? 215 TRP B O   1 
ATOM   5119  C  CB  . TRP B 1 215 ? 16.122  35.920  -4.372  1.00 26.95  ? 215 TRP B CB  1 
ATOM   5120  C  CG  . TRP B 1 215 ? 16.654  34.926  -3.461  1.00 34.44  ? 215 TRP B CG  1 
ATOM   5121  C  CD1 . TRP B 1 215 ? 17.954  34.516  -3.356  1.00 33.05  ? 215 TRP B CD1 1 
ATOM   5122  C  CD2 . TRP B 1 215 ? 15.909  34.181  -2.496  1.00 24.04  ? 215 TRP B CD2 1 
ATOM   5123  N  NE1 . TRP B 1 215 ? 18.061  33.546  -2.374  1.00 32.37  ? 215 TRP B NE1 1 
ATOM   5124  C  CE2 . TRP B 1 215 ? 16.824  33.333  -1.823  1.00 33.90  ? 215 TRP B CE2 1 
ATOM   5125  C  CE3 . TRP B 1 215 ? 14.566  34.151  -2.127  1.00 27.58  ? 215 TRP B CE3 1 
ATOM   5126  C  CZ2 . TRP B 1 215 ? 16.425  32.449  -0.809  1.00 24.21  ? 215 TRP B CZ2 1 
ATOM   5127  C  CZ3 . TRP B 1 215 ? 14.173  33.282  -1.109  1.00 27.03  ? 215 TRP B CZ3 1 
ATOM   5128  C  CH2 . TRP B 1 215 ? 15.102  32.451  -0.462  1.00 25.28  ? 215 TRP B CH2 1 
ATOM   5129  N  N   . ILE B 1 216 ? 16.870  38.709  -5.438  1.00 22.54  ? 216 ILE B N   1 
ATOM   5130  C  CA  . ILE B 1 216 ? 16.904  39.470  -6.673  1.00 26.85  ? 216 ILE B CA  1 
ATOM   5131  C  C   . ILE B 1 216 ? 17.785  38.657  -7.600  1.00 28.87  ? 216 ILE B C   1 
ATOM   5132  O  O   . ILE B 1 216 ? 19.022  38.714  -7.508  1.00 26.82  ? 216 ILE B O   1 
ATOM   5133  C  CB  . ILE B 1 216 ? 17.441  40.886  -6.477  1.00 29.01  ? 216 ILE B CB  1 
ATOM   5134  C  CG1 . ILE B 1 216 ? 16.528  41.633  -5.510  1.00 28.09  ? 216 ILE B CG1 1 
ATOM   5135  C  CG2 . ILE B 1 216 ? 17.550  41.590  -7.830  1.00 31.29  ? 216 ILE B CG2 1 
ATOM   5136  C  CD1 . ILE B 1 216 ? 17.092  42.959  -5.064  1.00 39.80  ? 216 ILE B CD1 1 
ATOM   5137  N  N   . ASP B 1 217 ? 17.150  37.881  -8.479  1.00 27.54  ? 217 ASP B N   1 
ATOM   5138  C  CA  . ASP B 1 217 ? 17.856  36.895  -9.292  1.00 29.11  ? 217 ASP B CA  1 
ATOM   5139  C  C   . ASP B 1 217 ? 18.251  37.546  -10.612 1.00 32.21  ? 217 ASP B C   1 
ATOM   5140  O  O   . ASP B 1 217 ? 17.577  37.423  -11.639 1.00 33.56  ? 217 ASP B O   1 
ATOM   5141  C  CB  . ASP B 1 217 ? 16.996  35.656  -9.496  1.00 24.34  ? 217 ASP B CB  1 
ATOM   5142  C  CG  . ASP B 1 217 ? 16.732  34.911  -8.195  1.00 28.84  ? 217 ASP B CG  1 
ATOM   5143  O  OD1 . ASP B 1 217 ? 17.711  34.511  -7.532  1.00 34.17  ? 217 ASP B OD1 1 
ATOM   5144  O  OD2 . ASP B 1 217 ? 15.554  34.712  -7.834  1.00 29.35  ? 217 ASP B OD2 1 
ATOM   5145  N  N   . THR B 1 218 ? 19.398  38.222  -10.576 1.00 27.58  ? 218 THR B N   1 
ATOM   5146  C  CA  . THR B 1 218 ? 19.900  38.933  -11.743 1.00 29.17  ? 218 THR B CA  1 
ATOM   5147  C  C   . THR B 1 218 ? 20.136  38.013  -12.930 1.00 35.70  ? 218 THR B C   1 
ATOM   5148  O  O   . THR B 1 218 ? 20.172  38.491  -14.064 1.00 29.18  ? 218 THR B O   1 
ATOM   5149  C  CB  . THR B 1 218 ? 21.195  39.638  -11.375 1.00 29.32  ? 218 THR B CB  1 
ATOM   5150  O  OG1 . THR B 1 218 ? 22.049  38.707  -10.705 1.00 32.96  ? 218 THR B OG1 1 
ATOM   5151  C  CG2 . THR B 1 218 ? 20.906  40.754  -10.416 1.00 31.35  ? 218 THR B CG2 1 
ATOM   5152  N  N   . ARG B 1 219 ? 20.293  36.706  -12.707 1.00 32.74  ? 219 ARG B N   1 
ATOM   5153  C  CA  . ARG B 1 219 ? 20.546  35.787  -13.808 1.00 34.43  ? 219 ARG B CA  1 
ATOM   5154  C  C   . ARG B 1 219 ? 19.275  35.089  -14.275 1.00 26.11  ? 219 ARG B C   1 
ATOM   5155  O  O   . ARG B 1 219 ? 19.349  34.113  -15.026 1.00 28.99  ? 219 ARG B O   1 
ATOM   5156  C  CB  . ARG B 1 219 ? 21.618  34.775  -13.415 1.00 30.29  ? 219 ARG B CB  1 
ATOM   5157  C  CG  . ARG B 1 219 ? 23.014  35.365  -13.395 1.00 30.42  ? 219 ARG B CG  1 
ATOM   5158  C  CD  . ARG B 1 219 ? 24.031  34.332  -12.899 1.00 36.48  ? 219 ARG B CD  1 
ATOM   5159  N  NE  . ARG B 1 219 ? 24.986  34.919  -11.965 1.00 39.91  ? 219 ARG B NE  1 
ATOM   5160  C  CZ  . ARG B 1 219 ? 25.756  34.220  -11.141 1.00 42.40  ? 219 ARG B CZ  1 
ATOM   5161  N  NH1 . ARG B 1 219 ? 25.671  32.905  -11.069 1.00 42.20  ? 219 ARG B NH1 1 
ATOM   5162  N  NH2 . ARG B 1 219 ? 26.632  34.857  -10.366 1.00 44.55  ? 219 ARG B NH2 1 
ATOM   5163  N  N   . LEU B 1 220 ? 18.116  35.629  -13.898 1.00 31.17  ? 220 LEU B N   1 
ATOM   5164  C  CA  . LEU B 1 220 ? 16.813  35.105  -14.304 1.00 31.17  ? 220 LEU B CA  1 
ATOM   5165  C  C   . LEU B 1 220 ? 16.774  34.559  -15.727 1.00 29.98  ? 220 LEU B C   1 
ATOM   5166  O  O   . LEU B 1 220 ? 16.319  33.434  -15.946 1.00 33.19  ? 220 LEU B O   1 
ATOM   5167  C  CB  . LEU B 1 220 ? 15.755  36.197  -14.133 1.00 29.41  ? 220 LEU B CB  1 
ATOM   5168  C  CG  . LEU B 1 220 ? 14.328  35.632  -14.171 1.00 26.48  ? 220 LEU B CG  1 
ATOM   5169  C  CD1 . LEU B 1 220 ? 14.171  34.570  -13.102 1.00 28.28  ? 220 LEU B CD1 1 
ATOM   5170  C  CD2 . LEU B 1 220 ? 13.256  36.706  -14.038 1.00 25.35  ? 220 LEU B CD2 1 
ATOM   5171  N  N   . HIS B 1 221 ? 17.209  35.341  -16.723 1.00 30.99  ? 221 HIS B N   1 
ATOM   5172  C  CA  . HIS B 1 221 ? 17.240  34.790  -18.074 1.00 29.55  ? 221 HIS B CA  1 
ATOM   5173  C  C   . HIS B 1 221 ? 18.639  34.846  -18.684 1.00 37.18  ? 221 HIS B C   1 
ATOM   5174  O  O   . HIS B 1 221 ? 18.821  35.382  -19.781 1.00 32.77  ? 221 HIS B O   1 
ATOM   5175  C  CB  . HIS B 1 221 ? 16.259  35.502  -19.006 1.00 33.61  ? 221 HIS B CB  1 
ATOM   5176  C  CG  . HIS B 1 221 ? 14.860  35.595  -18.486 1.00 31.28  ? 221 HIS B CG  1 
ATOM   5177  N  ND1 . HIS B 1 221 ? 14.427  36.638  -17.700 1.00 33.84  ? 221 HIS B ND1 1 
ATOM   5178  C  CD2 . HIS B 1 221 ? 13.786  34.795  -18.671 1.00 33.14  ? 221 HIS B CD2 1 
ATOM   5179  C  CE1 . HIS B 1 221 ? 13.153  36.466  -17.403 1.00 30.85  ? 221 HIS B CE1 1 
ATOM   5180  N  NE2 . HIS B 1 221 ? 12.741  35.353  -17.978 1.00 30.64  ? 221 HIS B NE2 1 
ATOM   5181  N  N   . SER B 1 222 ? 19.624  34.281  -17.987 1.00 35.92  ? 222 SER B N   1 
ATOM   5182  C  CA  . SER B 1 222 ? 21.010  34.258  -18.437 1.00 30.13  ? 222 SER B CA  1 
ATOM   5183  C  C   . SER B 1 222 ? 21.320  33.142  -19.438 1.00 37.30  ? 222 SER B C   1 
ATOM   5184  O  O   . SER B 1 222 ? 22.422  33.130  -19.998 1.00 40.56  ? 222 SER B O   1 
ATOM   5185  C  CB  . SER B 1 222 ? 21.940  34.136  -17.229 1.00 29.89  ? 222 SER B CB  1 
ATOM   5186  O  OG  . SER B 1 222 ? 22.134  32.777  -16.852 1.00 31.07  ? 222 SER B OG  1 
ATOM   5187  N  N   . SER B 1 223 ? 20.397  32.224  -19.710 1.00 34.44  ? 223 SER B N   1 
ATOM   5188  C  CA  . SER B 1 223 ? 20.688  31.099  -20.592 1.00 32.91  ? 223 SER B CA  1 
ATOM   5189  C  C   . SER B 1 223 ? 19.861  31.179  -21.869 1.00 28.59  ? 223 SER B C   1 
ATOM   5190  O  O   . SER B 1 223 ? 18.844  31.869  -21.930 1.00 33.53  ? 223 SER B O   1 
ATOM   5191  C  CB  . SER B 1 223 ? 20.419  29.772  -19.882 1.00 33.83  ? 223 SER B CB  1 
ATOM   5192  O  OG  . SER B 1 223 ? 20.888  29.844  -18.553 1.00 30.21  ? 223 SER B OG  1 
ATOM   5193  N  N   . GLY B 1 224 ? 20.318  30.470  -22.897 1.00 34.93  ? 224 GLY B N   1 
ATOM   5194  C  CA  . GLY B 1 224 ? 19.575  30.351  -24.129 1.00 39.76  ? 224 GLY B CA  1 
ATOM   5195  C  C   . GLY B 1 224 ? 19.939  31.404  -25.153 1.00 45.28  ? 224 GLY B C   1 
ATOM   5196  O  O   . GLY B 1 224 ? 20.722  32.321  -24.886 1.00 42.05  ? 224 GLY B O   1 
ATOM   5197  N  N   . PRO B 1 225 ? 19.362  31.299  -26.352 1.00 51.07  ? 225 PRO B N   1 
ATOM   5198  C  CA  . PRO B 1 225 ? 19.755  32.237  -27.416 1.00 49.24  ? 225 PRO B CA  1 
ATOM   5199  C  C   . PRO B 1 225 ? 19.252  33.634  -27.151 1.00 50.41  ? 225 PRO B C   1 
ATOM   5200  O  O   . PRO B 1 225 ? 19.889  34.616  -27.560 1.00 44.37  ? 225 PRO B O   1 
ATOM   5201  C  CB  . PRO B 1 225 ? 19.119  31.637  -28.678 1.00 53.94  ? 225 PRO B CB  1 
ATOM   5202  C  CG  . PRO B 1 225 ? 17.993  30.708  -28.179 1.00 47.04  ? 225 PRO B CG  1 
ATOM   5203  C  CD  . PRO B 1 225 ? 18.147  30.523  -26.690 1.00 49.23  ? 225 PRO B CD  1 
ATOM   5204  N  N   . ASN B 1 226 ? 18.122  33.743  -26.462 1.00 47.84  ? 226 ASN B N   1 
ATOM   5205  C  CA  . ASN B 1 226 ? 17.473  35.018  -26.203 1.00 44.74  ? 226 ASN B CA  1 
ATOM   5206  C  C   . ASN B 1 226 ? 17.843  35.528  -24.825 1.00 46.65  ? 226 ASN B C   1 
ATOM   5207  O  O   . ASN B 1 226 ? 17.033  36.136  -24.119 1.00 49.08  ? 226 ASN B O   1 
ATOM   5208  C  CB  . ASN B 1 226 ? 15.964  34.874  -26.367 1.00 46.77  ? 226 ASN B CB  1 
ATOM   5209  C  CG  . ASN B 1 226 ? 15.388  35.903  -27.321 1.00 53.27  ? 226 ASN B CG  1 
ATOM   5210  O  OD1 . ASN B 1 226 ? 16.073  36.859  -27.707 1.00 54.93  ? 226 ASN B OD1 1 
ATOM   5211  N  ND2 . ASN B 1 226 ? 14.139  35.695  -27.741 1.00 50.35  ? 226 ASN B ND2 1 
ATOM   5212  N  N   . GLY B 1 227 ? 19.088  35.277  -24.429 1.00 44.63  ? 227 GLY B N   1 
ATOM   5213  C  CA  . GLY B 1 227 ? 19.533  35.682  -23.112 1.00 38.87  ? 227 GLY B CA  1 
ATOM   5214  C  C   . GLY B 1 227 ? 19.520  37.188  -22.946 1.00 45.99  ? 227 GLY B C   1 
ATOM   5215  O  O   . GLY B 1 227 ? 19.728  37.949  -23.895 1.00 36.87  ? 227 GLY B O   1 
ATOM   5216  N  N   . ARG B 1 228 ? 19.270  37.614  -21.712 1.00 43.08  ? 228 ARG B N   1 
ATOM   5217  C  CA  . ARG B 1 228 ? 19.229  39.025  -21.373 1.00 38.30  ? 228 ARG B CA  1 
ATOM   5218  C  C   . ARG B 1 228 ? 19.657  39.189  -19.926 1.00 43.37  ? 228 ARG B C   1 
ATOM   5219  O  O   . ARG B 1 228 ? 19.947  38.216  -19.227 1.00 45.73  ? 228 ARG B O   1 
ATOM   5220  C  CB  . ARG B 1 228 ? 17.839  39.600  -21.608 1.00 43.33  ? 228 ARG B CB  1 
ATOM   5221  C  CG  . ARG B 1 228 ? 16.758  38.988  -20.740 1.00 40.27  ? 228 ARG B CG  1 
ATOM   5222  C  CD  . ARG B 1 228 ? 15.495  39.762  -20.983 1.00 35.42  ? 228 ARG B CD  1 
ATOM   5223  N  NE  . ARG B 1 228 ? 14.335  39.239  -20.276 1.00 39.06  ? 228 ARG B NE  1 
ATOM   5224  C  CZ  . ARG B 1 228 ? 13.573  38.261  -20.736 1.00 35.59  ? 228 ARG B CZ  1 
ATOM   5225  N  NH1 . ARG B 1 228 ? 13.874  37.625  -21.860 1.00 39.03  ? 228 ARG B NH1 1 
ATOM   5226  N  NH2 . ARG B 1 228 ? 12.477  37.917  -20.059 1.00 33.95  ? 228 ARG B NH2 1 
ATOM   5227  N  N   . ASP B 1 229 ? 19.685  40.430  -19.471 1.00 42.04  ? 229 ASP B N   1 
ATOM   5228  C  CA  . ASP B 1 229 ? 20.086  40.724  -18.111 1.00 41.41  ? 229 ASP B CA  1 
ATOM   5229  C  C   . ASP B 1 229 ? 18.916  41.367  -17.380 1.00 38.61  ? 229 ASP B C   1 
ATOM   5230  O  O   . ASP B 1 229 ? 17.969  41.847  -18.000 1.00 39.38  ? 229 ASP B O   1 
ATOM   5231  C  CB  . ASP B 1 229 ? 21.316  41.634  -18.087 1.00 48.07  ? 229 ASP B CB  1 
ATOM   5232  C  CG  . ASP B 1 229 ? 22.418  41.085  -17.216 1.00 51.79  ? 229 ASP B CG  1 
ATOM   5233  O  OD1 . ASP B 1 229 ? 23.597  41.375  -17.511 1.00 56.13  ? 229 ASP B OD1 1 
ATOM   5234  O  OD2 . ASP B 1 229 ? 22.099  40.362  -16.240 1.00 49.96  ? 229 ASP B OD2 1 
ATOM   5235  N  N   . MET B 1 230 ? 18.962  41.326  -16.049 1.00 39.83  ? 230 MET B N   1 
ATOM   5236  C  CA  . MET B 1 230 ? 17.902  41.908  -15.235 1.00 37.88  ? 230 MET B CA  1 
ATOM   5237  C  C   . MET B 1 230 ? 18.066  43.427  -15.163 1.00 39.48  ? 230 MET B C   1 
ATOM   5238  O  O   . MET B 1 230 ? 19.091  43.913  -14.681 1.00 36.44  ? 230 MET B O   1 
ATOM   5239  C  CB  . MET B 1 230 ? 17.927  41.315  -13.831 1.00 37.11  ? 230 MET B CB  1 
ATOM   5240  C  CG  . MET B 1 230 ? 17.114  42.126  -12.824 1.00 34.19  ? 230 MET B CG  1 
ATOM   5241  S  SD  . MET B 1 230 ? 16.555  41.175  -11.416 1.00 35.41  ? 230 MET B SD  1 
ATOM   5242  C  CE  . MET B 1 230 ? 15.315  40.109  -12.171 1.00 35.60  ? 230 MET B CE  1 
ATOM   5243  N  N   . THR B 1 231 ? 17.045  44.170  -15.597 1.00 36.88  ? 231 THR B N   1 
ATOM   5244  C  CA  . THR B 1 231 ? 17.041  45.627  -15.494 1.00 36.44  ? 231 THR B CA  1 
ATOM   5245  C  C   . THR B 1 231 ? 16.695  46.081  -14.077 1.00 37.60  ? 231 THR B C   1 
ATOM   5246  O  O   . THR B 1 231 ? 16.112  45.334  -13.286 1.00 35.93  ? 231 THR B O   1 
ATOM   5247  C  CB  . THR B 1 231 ? 16.041  46.252  -16.477 1.00 36.17  ? 231 THR B CB  1 
ATOM   5248  O  OG1 . THR B 1 231 ? 14.703  46.044  -16.007 1.00 33.56  ? 231 THR B OG1 1 
ATOM   5249  C  CG2 . THR B 1 231 ? 16.197  45.662  -17.887 1.00 36.27  ? 231 THR B CG2 1 
ATOM   5250  N  N   . VAL B 1 232 ? 17.035  47.346  -13.783 1.00 29.26  ? 232 VAL B N   1 
ATOM   5251  C  CA  . VAL B 1 232 ? 16.726  47.957  -12.488 1.00 31.13  ? 232 VAL B CA  1 
ATOM   5252  C  C   . VAL B 1 232 ? 15.234  47.891  -12.183 1.00 34.93  ? 232 VAL B C   1 
ATOM   5253  O  O   . VAL B 1 232 ? 14.824  47.621  -11.044 1.00 31.07  ? 232 VAL B O   1 
ATOM   5254  C  CB  . VAL B 1 232 ? 17.215  49.415  -12.460 1.00 32.14  ? 232 VAL B CB  1 
ATOM   5255  C  CG1 . VAL B 1 232 ? 16.479  50.204  -11.381 1.00 32.46  ? 232 VAL B CG1 1 
ATOM   5256  C  CG2 . VAL B 1 232 ? 18.737  49.484  -12.276 1.00 31.29  ? 232 VAL B CG2 1 
ATOM   5257  N  N   . GLU B 1 233 ? 14.403  48.190  -13.181 1.00 30.18  ? 233 GLU B N   1 
ATOM   5258  C  CA  . GLU B 1 233 ? 12.971  48.280  -12.957 1.00 26.38  ? 233 GLU B CA  1 
ATOM   5259  C  C   . GLU B 1 233 ? 12.386  46.912  -12.649 1.00 31.67  ? 233 GLU B C   1 
ATOM   5260  O  O   . GLU B 1 233 ? 11.439  46.797  -11.862 1.00 27.83  ? 233 GLU B O   1 
ATOM   5261  C  CB  . GLU B 1 233 ? 12.291  48.883  -14.187 1.00 28.45  ? 233 GLU B CB  1 
ATOM   5262  C  CG  . GLU B 1 233 ? 12.618  50.357  -14.440 1.00 32.68  ? 233 GLU B CG  1 
ATOM   5263  C  CD  . GLU B 1 233 ? 13.935  50.562  -15.167 1.00 36.36  ? 233 GLU B CD  1 
ATOM   5264  O  OE1 . GLU B 1 233 ? 14.435  49.605  -15.815 1.00 33.60  ? 233 GLU B OE1 1 
ATOM   5265  O  OE2 . GLU B 1 233 ? 14.470  51.692  -15.082 1.00 41.22  ? 233 GLU B OE2 1 
ATOM   5266  N  N   . GLU B 1 234 ? 12.919  45.875  -13.296 1.00 27.56  ? 234 GLU B N   1 
ATOM   5267  C  CA  . GLU B 1 234 ? 12.523  44.510  -12.990 1.00 29.73  ? 234 GLU B CA  1 
ATOM   5268  C  C   . GLU B 1 234 ? 13.031  44.104  -11.618 1.00 34.11  ? 234 GLU B C   1 
ATOM   5269  O  O   . GLU B 1 234 ? 12.304  43.479  -10.837 1.00 30.14  ? 234 GLU B O   1 
ATOM   5270  C  CB  . GLU B 1 234 ? 13.060  43.581  -14.074 1.00 33.83  ? 234 GLU B CB  1 
ATOM   5271  C  CG  . GLU B 1 234 ? 12.438  43.861  -15.454 1.00 29.99  ? 234 GLU B CG  1 
ATOM   5272  C  CD  . GLU B 1 234 ? 13.188  43.195  -16.588 1.00 35.43  ? 234 GLU B CD  1 
ATOM   5273  O  OE1 . GLU B 1 234 ? 14.297  42.672  -16.338 1.00 37.10  ? 234 GLU B OE1 1 
ATOM   5274  O  OE2 . GLU B 1 234 ? 12.670  43.196  -17.730 1.00 33.77  ? 234 GLU B OE2 1 
ATOM   5275  N  N   . GLY B 1 235 ? 14.280  44.456  -11.310 1.00 28.99  ? 235 GLY B N   1 
ATOM   5276  C  CA  . GLY B 1 235 ? 14.819  44.149  -10.003 1.00 29.96  ? 235 GLY B CA  1 
ATOM   5277  C  C   . GLY B 1 235 ? 14.044  44.840  -8.901  1.00 33.95  ? 235 GLY B C   1 
ATOM   5278  O  O   . GLY B 1 235 ? 13.697  44.222  -7.892  1.00 29.26  ? 235 GLY B O   1 
ATOM   5279  N  N   . ALA B 1 236 ? 13.752  46.128  -9.086  1.00 31.01  ? 236 ALA B N   1 
ATOM   5280  C  CA  . ALA B 1 236 ? 12.979  46.859  -8.092  1.00 31.98  ? 236 ALA B CA  1 
ATOM   5281  C  C   . ALA B 1 236 ? 11.539  46.362  -8.007  1.00 28.95  ? 236 ALA B C   1 
ATOM   5282  O  O   . ALA B 1 236 ? 10.955  46.371  -6.921  1.00 29.22  ? 236 ALA B O   1 
ATOM   5283  C  CB  . ALA B 1 236 ? 13.001  48.361  -8.398  1.00 32.51  ? 236 ALA B CB  1 
ATOM   5284  N  N   . ALA B 1 237 ? 10.941  45.951  -9.131  1.00 27.68  ? 237 ALA B N   1 
ATOM   5285  C  CA  . ALA B 1 237 ? 9.601   45.375  -9.074  1.00 29.33  ? 237 ALA B CA  1 
ATOM   5286  C  C   . ALA B 1 237 ? 9.596   44.083  -8.255  1.00 31.42  ? 237 ALA B C   1 
ATOM   5287  O  O   . ALA B 1 237 ? 8.646   43.817  -7.510  1.00 32.45  ? 237 ALA B O   1 
ATOM   5288  C  CB  . ALA B 1 237 ? 9.064   45.120  -10.488 1.00 32.14  ? 237 ALA B CB  1 
ATOM   5289  N  N   . ALA B 1 238 ? 10.658  43.275  -8.376  1.00 32.58  ? 238 ALA B N   1 
ATOM   5290  C  CA  . ALA B 1 238 ? 10.776  42.039  -7.602  1.00 35.55  ? 238 ALA B CA  1 
ATOM   5291  C  C   . ALA B 1 238 ? 10.979  42.320  -6.121  1.00 33.21  ? 238 ALA B C   1 
ATOM   5292  O  O   . ALA B 1 238 ? 10.413  41.621  -5.269  1.00 34.75  ? 238 ALA B O   1 
ATOM   5293  C  CB  . ALA B 1 238 ? 11.927  41.185  -8.131  1.00 29.21  ? 238 ALA B CB  1 
ATOM   5294  N  N   . LEU B 1 239 ? 11.797  43.319  -5.791  1.00 34.26  ? 239 LEU B N   1 
ATOM   5295  C  CA  . LEU B 1 239 ? 11.958  43.712  -4.390  1.00 29.57  ? 239 LEU B CA  1 
ATOM   5296  C  C   . LEU B 1 239 ? 10.666  44.283  -3.811  1.00 32.53  ? 239 LEU B C   1 
ATOM   5297  O  O   . LEU B 1 239 ? 10.272  43.945  -2.689  1.00 27.82  ? 239 LEU B O   1 
ATOM   5298  C  CB  . LEU B 1 239 ? 13.088  44.733  -4.255  1.00 33.45  ? 239 LEU B CB  1 
ATOM   5299  C  CG  . LEU B 1 239 ? 13.443  45.128  -2.822  1.00 33.26  ? 239 LEU B CG  1 
ATOM   5300  C  CD1 . LEU B 1 239 ? 13.414  43.899  -1.886  1.00 31.64  ? 239 LEU B CD1 1 
ATOM   5301  C  CD2 . LEU B 1 239 ? 14.806  45.739  -2.782  1.00 31.79  ? 239 LEU B CD2 1 
ATOM   5302  N  N   . GLN B 1 240 ? 10.023  45.201  -4.535  1.00 30.40  ? 240 GLN B N   1 
ATOM   5303  C  CA  . GLN B 1 240 ? 8.781   45.790  -4.040  1.00 29.67  ? 240 GLN B CA  1 
ATOM   5304  C  C   . GLN B 1 240 ? 7.718   44.727  -3.852  1.00 33.31  ? 240 GLN B C   1 
ATOM   5305  O  O   . GLN B 1 240 ? 6.864   44.849  -2.966  1.00 33.84  ? 240 GLN B O   1 
ATOM   5306  C  CB  . GLN B 1 240 ? 8.283   46.878  -5.004  1.00 33.30  ? 240 GLN B CB  1 
ATOM   5307  C  CG  . GLN B 1 240 ? 9.163   48.142  -5.050  1.00 36.77  ? 240 GLN B CG  1 
ATOM   5308  C  CD  . GLN B 1 240 ? 8.957   48.987  -6.315  1.00 39.49  ? 240 GLN B CD  1 
ATOM   5309  O  OE1 . GLN B 1 240 ? 7.967   48.835  -7.035  1.00 41.04  ? 240 GLN B OE1 1 
ATOM   5310  N  NE2 . GLN B 1 240 ? 9.883   49.898  -6.565  1.00 35.45  ? 240 GLN B NE2 1 
ATOM   5311  N  N   . ARG B 1 241 ? 7.767   43.691  -4.692  1.00 28.64  ? 241 ARG B N   1 
ATOM   5312  C  CA  A ARG B 1 241 ? 6.856   42.560  -4.572  0.58 32.81  ? 241 ARG B CA  1 
ATOM   5313  C  CA  B ARG B 1 241 ? 6.856   42.561  -4.572  0.42 30.95  ? 241 ARG B CA  1 
ATOM   5314  C  C   . ARG B 1 241 ? 7.087   41.807  -3.265  1.00 29.14  ? 241 ARG B C   1 
ATOM   5315  O  O   . ARG B 1 241 ? 6.138   41.472  -2.550  1.00 28.95  ? 241 ARG B O   1 
ATOM   5316  C  CB  A ARG B 1 241 ? 7.044   41.643  -5.784  0.58 33.02  ? 241 ARG B CB  1 
ATOM   5317  C  CB  B ARG B 1 241 ? 7.032   41.651  -5.794  0.42 30.71  ? 241 ARG B CB  1 
ATOM   5318  C  CG  A ARG B 1 241 ? 6.313   40.308  -5.754  0.58 32.76  ? 241 ARG B CG  1 
ATOM   5319  C  CG  B ARG B 1 241 ? 7.233   40.167  -5.515  0.42 33.18  ? 241 ARG B CG  1 
ATOM   5320  C  CD  A ARG B 1 241 ? 7.116   39.232  -6.535  0.58 32.29  ? 241 ARG B CD  1 
ATOM   5321  C  CD  B ARG B 1 241 ? 7.018   39.312  -6.771  0.42 32.18  ? 241 ARG B CD  1 
ATOM   5322  N  NE  A ARG B 1 241 ? 8.512   39.142  -6.109  0.58 28.07  ? 241 ARG B NE  1 
ATOM   5323  N  NE  B ARG B 1 241 ? 5.638   38.861  -6.800  0.42 29.15  ? 241 ARG B NE  1 
ATOM   5324  C  CZ  A ARG B 1 241 ? 9.474   38.532  -6.785  0.58 31.10  ? 241 ARG B CZ  1 
ATOM   5325  C  CZ  B ARG B 1 241 ? 4.618   39.587  -7.237  0.42 30.75  ? 241 ARG B CZ  1 
ATOM   5326  N  NH1 A ARG B 1 241 ? 9.263   38.042  -7.997  0.58 35.19  ? 241 ARG B NH1 1 
ATOM   5327  N  NH1 B ARG B 1 241 ? 4.803   40.695  -7.934  0.42 32.81  ? 241 ARG B NH1 1 
ATOM   5328  N  NH2 A ARG B 1 241 ? 10.672  38.383  -6.222  0.58 26.45  ? 241 ARG B NH2 1 
ATOM   5329  N  NH2 B ARG B 1 241 ? 3.383   39.200  -6.952  0.42 34.43  ? 241 ARG B NH2 1 
ATOM   5330  N  N   . ASP B 1 242 ? 8.341   41.549  -2.922  1.00 26.79  ? 242 ASP B N   1 
ATOM   5331  C  CA  . ASP B 1 242 ? 8.580   40.860  -1.664  1.00 29.46  ? 242 ASP B CA  1 
ATOM   5332  C  C   . ASP B 1 242 ? 8.326   41.766  -0.471  1.00 29.66  ? 242 ASP B C   1 
ATOM   5333  O  O   . ASP B 1 242 ? 7.890   41.282  0.579   1.00 29.15  ? 242 ASP B O   1 
ATOM   5334  C  CB  . ASP B 1 242 ? 9.988   40.294  -1.628  1.00 27.81  ? 242 ASP B CB  1 
ATOM   5335  C  CG  . ASP B 1 242 ? 10.182  39.200  -2.657  1.00 35.94  ? 242 ASP B CG  1 
ATOM   5336  O  OD1 . ASP B 1 242 ? 9.223   38.413  -2.857  1.00 34.95  ? 242 ASP B OD1 1 
ATOM   5337  O  OD2 . ASP B 1 242 ? 11.261  39.154  -3.298  1.00 33.64  ? 242 ASP B OD2 1 
ATOM   5338  N  N   . LEU B 1 243 ? 8.571   43.071  -0.601  1.00 26.68  ? 243 LEU B N   1 
ATOM   5339  C  CA  . LEU B 1 243 ? 8.233   43.983  0.497   1.00 29.97  ? 243 LEU B CA  1 
ATOM   5340  C  C   . LEU B 1 243 ? 6.755   43.883  0.859   1.00 28.45  ? 243 LEU B C   1 
ATOM   5341  O  O   . LEU B 1 243 ? 6.404   43.784  2.041   1.00 29.86  ? 243 LEU B O   1 
ATOM   5342  C  CB  . LEU B 1 243 ? 8.592   45.436  0.140   1.00 30.80  ? 243 LEU B CB  1 
ATOM   5343  C  CG  . LEU B 1 243 ? 10.075  45.797  0.004   1.00 32.51  ? 243 LEU B CG  1 
ATOM   5344  C  CD1 . LEU B 1 243 ? 10.331  47.322  -0.054  1.00 31.16  ? 243 LEU B CD1 1 
ATOM   5345  C  CD2 . LEU B 1 243 ? 10.898  45.133  1.087   1.00 28.93  ? 243 LEU B CD2 1 
ATOM   5346  N  N   . ARG B 1 244 ? 5.876   43.881  -0.150  1.00 26.53  ? 244 ARG B N   1 
ATOM   5347  C  CA  . ARG B 1 244 ? 4.444   43.818  0.106   1.00 28.44  ? 244 ARG B CA  1 
ATOM   5348  C  C   . ARG B 1 244 ? 4.060   42.474  0.725   1.00 29.29  ? 244 ARG B C   1 
ATOM   5349  O  O   . ARG B 1 244 ? 3.285   42.417  1.689   1.00 27.60  ? 244 ARG B O   1 
ATOM   5350  C  CB  . ARG B 1 244 ? 3.675   44.061  -1.199  1.00 32.35  ? 244 ARG B CB  1 
ATOM   5351  C  CG  . ARG B 1 244 ? 3.800   45.502  -1.733  1.00 30.29  ? 244 ARG B CG  1 
ATOM   5352  C  CD  . ARG B 1 244 ? 2.939   45.720  -2.952  1.00 37.51  ? 244 ARG B CD  1 
ATOM   5353  N  NE  . ARG B 1 244 ? 3.493   46.754  -3.820  1.00 35.99  ? 244 ARG B NE  1 
ATOM   5354  C  CZ  . ARG B 1 244 ? 4.027   46.523  -5.013  1.00 46.84  ? 244 ARG B CZ  1 
ATOM   5355  N  NH1 . ARG B 1 244 ? 4.103   45.294  -5.510  1.00 37.78  ? 244 ARG B NH1 1 
ATOM   5356  N  NH2 . ARG B 1 244 ? 4.490   47.552  -5.731  1.00 45.22  ? 244 ARG B NH2 1 
ATOM   5357  N  N   . LEU B 1 245 ? 4.587   41.378  0.171   1.00 30.32  ? 245 LEU B N   1 
ATOM   5358  C  CA  . LEU B 1 245 ? 4.336   40.060  0.739   1.00 28.38  ? 245 LEU B CA  1 
ATOM   5359  C  C   . LEU B 1 245 ? 4.759   40.015  2.196   1.00 29.48  ? 245 LEU B C   1 
ATOM   5360  O  O   . LEU B 1 245 ? 4.008   39.543  3.061   1.00 26.85  ? 245 LEU B O   1 
ATOM   5361  C  CB  . LEU B 1 245 ? 5.074   38.987  -0.062  1.00 29.16  ? 245 LEU B CB  1 
ATOM   5362  C  CG  . LEU B 1 245 ? 4.849   37.558  0.449   1.00 30.11  ? 245 LEU B CG  1 
ATOM   5363  C  CD1 . LEU B 1 245 ? 3.360   37.202  0.438   1.00 28.57  ? 245 LEU B CD1 1 
ATOM   5364  C  CD2 . LEU B 1 245 ? 5.650   36.559  -0.368  1.00 26.68  ? 245 LEU B CD2 1 
ATOM   5365  N  N   . ALA B 1 246 ? 5.957   40.528  2.490   1.00 25.63  ? 246 ALA B N   1 
ATOM   5366  C  CA  . ALA B 1 246 ? 6.445   40.498  3.861   1.00 25.26  ? 246 ALA B CA  1 
ATOM   5367  C  C   . ALA B 1 246 ? 5.543   41.306  4.790   1.00 31.75  ? 246 ALA B C   1 
ATOM   5368  O  O   . ALA B 1 246 ? 5.227   40.862  5.904   1.00 27.84  ? 246 ALA B O   1 
ATOM   5369  C  CB  . ALA B 1 246 ? 7.876   41.005  3.921   1.00 23.69  ? 246 ALA B CB  1 
ATOM   5370  N  N   . LYS B 1 247 ? 5.095   42.482  4.344   1.00 28.31  ? 247 LYS B N   1 
ATOM   5371  C  CA  . LYS B 1 247 ? 4.157   43.260  5.147   1.00 27.82  ? 247 LYS B CA  1 
ATOM   5372  C  C   . LYS B 1 247 ? 2.847   42.515  5.350   1.00 25.71  ? 247 LYS B C   1 
ATOM   5373  O  O   . LYS B 1 247 ? 2.282   42.514  6.448   1.00 26.47  ? 247 LYS B O   1 
ATOM   5374  C  CB  . LYS B 1 247 ? 3.867   44.606  4.491   1.00 25.86  ? 247 LYS B CB  1 
ATOM   5375  C  CG  . LYS B 1 247 ? 2.901   45.448  5.283   1.00 25.51  ? 247 LYS B CG  1 
ATOM   5376  C  CD  . LYS B 1 247 ? 3.545   45.941  6.558   1.00 32.61  ? 247 LYS B CD  1 
ATOM   5377  C  CE  . LYS B 1 247 ? 2.663   46.955  7.266   1.00 31.41  ? 247 LYS B CE  1 
ATOM   5378  N  NZ  . LYS B 1 247 ? 3.131   47.112  8.654   1.00 41.96  ? 247 LYS B NZ  1 
ATOM   5379  N  N   . ARG B 1 248 ? 2.310   41.931  4.283   1.00 29.26  ? 248 ARG B N   1 
ATOM   5380  C  CA  . ARG B 1 248 ? 1.028   41.257  4.401   1.00 25.35  ? 248 ARG B CA  1 
ATOM   5381  C  C   . ARG B 1 248 ? 1.105   40.099  5.391   1.00 25.68  ? 248 ARG B C   1 
ATOM   5382  O  O   . ARG B 1 248 ? 0.117   39.774  6.056   1.00 23.56  ? 248 ARG B O   1 
ATOM   5383  C  CB  . ARG B 1 248 ? 0.583   40.775  3.030   1.00 25.72  ? 248 ARG B CB  1 
ATOM   5384  C  CG  . ARG B 1 248 ? -0.625  39.893  3.058   1.00 34.20  ? 248 ARG B CG  1 
ATOM   5385  C  CD  . ARG B 1 248 ? -0.968  39.468  1.661   1.00 38.97  ? 248 ARG B CD  1 
ATOM   5386  N  NE  . ARG B 1 248 ? -2.069  38.521  1.655   1.00 36.69  ? 248 ARG B NE  1 
ATOM   5387  C  CZ  . ARG B 1 248 ? -2.574  37.998  0.548   1.00 39.03  ? 248 ARG B CZ  1 
ATOM   5388  N  NH1 . ARG B 1 248 ? -2.100  38.327  -0.648  1.00 43.61  ? 248 ARG B NH1 1 
ATOM   5389  N  NH2 . ARG B 1 248 ? -3.572  37.124  0.640   1.00 32.69  ? 248 ARG B NH2 1 
ATOM   5390  N  N   . LEU B 1 249 ? 2.267   39.474  5.498   1.00 27.51  ? 249 LEU B N   1 
ATOM   5391  C  CA  . LEU B 1 249 ? 2.495   38.377  6.420   1.00 24.83  ? 249 LEU B CA  1 
ATOM   5392  C  C   . LEU B 1 249 ? 3.054   38.851  7.755   1.00 27.96  ? 249 LEU B C   1 
ATOM   5393  O  O   . LEU B 1 249 ? 3.248   38.036  8.660   1.00 24.33  ? 249 LEU B O   1 
ATOM   5394  C  CB  . LEU B 1 249 ? 3.427   37.352  5.768   1.00 24.68  ? 249 LEU B CB  1 
ATOM   5395  C  CG  . LEU B 1 249 ? 2.837   36.736  4.506   1.00 19.80  ? 249 LEU B CG  1 
ATOM   5396  C  CD1 . LEU B 1 249 ? 3.805   35.719  3.952   1.00 22.32  ? 249 LEU B CD1 1 
ATOM   5397  C  CD2 . LEU B 1 249 ? 1.500   36.068  4.790   1.00 25.02  ? 249 LEU B CD2 1 
ATOM   5398  N  N   . GLY B 1 250 ? 3.304   40.150  7.898   1.00 27.99  ? 250 GLY B N   1 
ATOM   5399  C  CA  . GLY B 1 250 ? 3.649   40.710  9.184   1.00 27.12  ? 250 GLY B CA  1 
ATOM   5400  C  C   . GLY B 1 250 ? 5.110   40.720  9.536   1.00 24.76  ? 250 GLY B C   1 
ATOM   5401  O  O   . GLY B 1 250 ? 5.434   40.908  10.713  1.00 30.51  ? 250 GLY B O   1 
ATOM   5402  N  N   . PHE B 1 251 ? 6.010   40.521  8.573   1.00 25.77  ? 251 PHE B N   1 
ATOM   5403  C  CA  . PHE B 1 251 ? 7.429   40.575  8.897   1.00 25.76  ? 251 PHE B CA  1 
ATOM   5404  C  C   . PHE B 1 251 ? 7.854   42.025  9.059   1.00 27.19  ? 251 PHE B C   1 
ATOM   5405  O  O   . PHE B 1 251 ? 7.176   42.945  8.608   1.00 32.64  ? 251 PHE B O   1 
ATOM   5406  C  CB  . PHE B 1 251 ? 8.283   39.882  7.824   1.00 28.16  ? 251 PHE B CB  1 
ATOM   5407  C  CG  . PHE B 1 251 ? 8.119   38.376  7.802   1.00 25.79  ? 251 PHE B CG  1 
ATOM   5408  C  CD1 . PHE B 1 251 ? 7.075   37.790  7.091   1.00 24.01  ? 251 PHE B CD1 1 
ATOM   5409  C  CD2 . PHE B 1 251 ? 8.978   37.558  8.517   1.00 22.77  ? 251 PHE B CD2 1 
ATOM   5410  C  CE1 . PHE B 1 251 ? 6.895   36.412  7.091   1.00 24.44  ? 251 PHE B CE1 1 
ATOM   5411  C  CE2 . PHE B 1 251 ? 8.803   36.180  8.519   1.00 30.52  ? 251 PHE B CE2 1 
ATOM   5412  C  CZ  . PHE B 1 251 ? 7.762   35.611  7.815   1.00 23.58  ? 251 PHE B CZ  1 
ATOM   5413  N  N   . ARG B 1 252 ? 8.966   42.229  9.756   1.00 28.94  ? 252 ARG B N   1 
ATOM   5414  C  CA  . ARG B 1 252 ? 9.518   43.564  9.888   1.00 34.42  ? 252 ARG B CA  1 
ATOM   5415  C  C   . ARG B 1 252 ? 10.795  43.759  9.087   1.00 35.53  ? 252 ARG B C   1 
ATOM   5416  O  O   . ARG B 1 252 ? 11.177  44.906  8.838   1.00 38.86  ? 252 ARG B O   1 
ATOM   5417  C  CB  . ARG B 1 252 ? 9.771   43.908  11.365  1.00 37.94  ? 252 ARG B CB  1 
ATOM   5418  C  CG  . ARG B 1 252 ? 10.136  42.729  12.240  1.00 44.17  ? 252 ARG B CG  1 
ATOM   5419  C  CD  . ARG B 1 252 ? 9.619   42.929  13.676  1.00 47.48  ? 252 ARG B CD  1 
ATOM   5420  N  NE  . ARG B 1 252 ? 10.250  44.080  14.308  1.00 51.15  ? 252 ARG B NE  1 
ATOM   5421  C  CZ  . ARG B 1 252 ? 11.273  44.008  15.151  1.00 52.65  ? 252 ARG B CZ  1 
ATOM   5422  N  NH1 . ARG B 1 252 ? 11.773  42.845  15.534  1.00 52.85  ? 252 ARG B NH1 1 
ATOM   5423  N  NH2 . ARG B 1 252 ? 11.812  45.131  15.618  1.00 54.92  ? 252 ARG B NH2 1 
ATOM   5424  N  N   . PHE B 1 253 ? 11.435  42.681  8.639   1.00 32.26  ? 253 PHE B N   1 
ATOM   5425  C  CA  . PHE B 1 253 ? 12.652  42.773  7.847   1.00 32.42  ? 253 PHE B CA  1 
ATOM   5426  C  C   . PHE B 1 253 ? 12.483  42.006  6.543   1.00 31.61  ? 253 PHE B C   1 
ATOM   5427  O  O   . PHE B 1 253 ? 11.781  40.990  6.489   1.00 32.83  ? 253 PHE B O   1 
ATOM   5428  C  CB  . PHE B 1 253 ? 13.847  42.210  8.616   1.00 29.17  ? 253 PHE B CB  1 
ATOM   5429  C  CG  . PHE B 1 253 ? 14.037  42.817  9.985   1.00 36.88  ? 253 PHE B CG  1 
ATOM   5430  C  CD1 . PHE B 1 253 ? 14.386  44.151  10.125  1.00 34.81  ? 253 PHE B CD1 1 
ATOM   5431  C  CD2 . PHE B 1 253 ? 13.878  42.048  11.129  1.00 36.50  ? 253 PHE B CD2 1 
ATOM   5432  C  CE1 . PHE B 1 253 ? 14.574  44.710  11.375  1.00 35.18  ? 253 PHE B CE1 1 
ATOM   5433  C  CE2 . PHE B 1 253 ? 14.071  42.602  12.388  1.00 41.27  ? 253 PHE B CE2 1 
ATOM   5434  C  CZ  . PHE B 1 253 ? 14.424  43.937  12.508  1.00 36.72  ? 253 PHE B CZ  1 
ATOM   5435  N  N   . VAL B 1 254 ? 13.136  42.493  5.495   1.00 26.39  ? 254 VAL B N   1 
ATOM   5436  C  CA  . VAL B 1 254 ? 13.296  41.739  4.258   1.00 29.48  ? 254 VAL B CA  1 
ATOM   5437  C  C   . VAL B 1 254 ? 14.766  41.740  3.881   1.00 31.77  ? 254 VAL B C   1 
ATOM   5438  O  O   . VAL B 1 254 ? 15.357  42.810  3.679   1.00 32.48  ? 254 VAL B O   1 
ATOM   5439  C  CB  . VAL B 1 254 ? 12.453  42.298  3.100   1.00 32.47  ? 254 VAL B CB  1 
ATOM   5440  C  CG1 . VAL B 1 254 ? 12.850  41.612  1.806   1.00 29.20  ? 254 VAL B CG1 1 
ATOM   5441  C  CG2 . VAL B 1 254 ? 11.007  42.027  3.347   1.00 28.14  ? 254 VAL B CG2 1 
ATOM   5442  N  N   . ARG B 1 255 ? 15.346  40.541  3.738   1.00 26.76  ? 255 ARG B N   1 
ATOM   5443  C  CA  . ARG B 1 255 ? 16.724  40.382  3.306   1.00 25.93  ? 255 ARG B CA  1 
ATOM   5444  C  C   . ARG B 1 255 ? 16.756  40.050  1.815   1.00 34.62  ? 255 ARG B C   1 
ATOM   5445  O  O   . ARG B 1 255 ? 16.621  38.871  1.445   1.00 31.55  ? 255 ARG B O   1 
ATOM   5446  C  CB  . ARG B 1 255 ? 17.419  39.287  4.116   1.00 31.64  ? 255 ARG B CB  1 
ATOM   5447  C  CG  . ARG B 1 255 ? 18.870  39.086  3.740   1.00 29.99  ? 255 ARG B CG  1 
ATOM   5448  C  CD  . ARG B 1 255 ? 19.185  37.623  3.614   1.00 32.77  ? 255 ARG B CD  1 
ATOM   5449  N  NE  . ARG B 1 255 ? 18.562  37.038  2.435   1.00 29.56  ? 255 ARG B NE  1 
ATOM   5450  C  CZ  . ARG B 1 255 ? 18.695  35.767  2.074   1.00 35.53  ? 255 ARG B CZ  1 
ATOM   5451  N  NH1 . ARG B 1 255 ? 19.442  34.927  2.773   1.00 34.53  ? 255 ARG B NH1 1 
ATOM   5452  N  NH2 . ARG B 1 255 ? 18.075  35.335  0.974   1.00 29.10  ? 255 ARG B NH2 1 
ATOM   5453  N  N   . PRO B 1 256 ? 16.969  41.026  0.926   1.00 33.30  ? 256 PRO B N   1 
ATOM   5454  C  CA  . PRO B 1 256 ? 17.160  40.699  -0.497  1.00 32.24  ? 256 PRO B CA  1 
ATOM   5455  C  C   . PRO B 1 256 ? 18.553  40.133  -0.715  1.00 36.33  ? 256 PRO B C   1 
ATOM   5456  O  O   . PRO B 1 256 ? 19.553  40.792  -0.421  1.00 40.01  ? 256 PRO B O   1 
ATOM   5457  C  CB  . PRO B 1 256 ? 16.984  42.052  -1.201  1.00 31.76  ? 256 PRO B CB  1 
ATOM   5458  C  CG  . PRO B 1 256 ? 17.420  43.072  -0.176  1.00 31.26  ? 256 PRO B CG  1 
ATOM   5459  C  CD  . PRO B 1 256 ? 17.228  42.453  1.207   1.00 35.17  ? 256 PRO B CD  1 
ATOM   5460  N  N   . LYS B 1 257 ? 18.615  38.904  -1.232  1.00 33.88  ? 257 LYS B N   1 
ATOM   5461  C  CA  . LYS B 1 257 ? 19.876  38.285  -1.643  1.00 35.96  ? 257 LYS B CA  1 
ATOM   5462  C  C   . LYS B 1 257 ? 20.077  38.631  -3.116  1.00 37.68  ? 257 LYS B C   1 
ATOM   5463  O  O   . LYS B 1 257 ? 19.413  38.070  -3.992  1.00 30.19  ? 257 LYS B O   1 
ATOM   5464  C  CB  . LYS B 1 257 ? 19.850  36.777  -1.398  1.00 31.15  ? 257 LYS B CB  1 
ATOM   5465  C  CG  . LYS B 1 257 ? 21.156  36.036  -1.767  1.00 34.95  ? 257 LYS B CG  1 
ATOM   5466  C  CD  . LYS B 1 257 ? 22.356  36.463  -0.925  1.00 37.19  ? 257 LYS B CD  1 
ATOM   5467  C  CE  . LYS B 1 257 ? 22.479  35.617  0.357   1.00 39.45  ? 257 LYS B CE  1 
ATOM   5468  N  NZ  . LYS B 1 257 ? 23.528  34.546  0.243   1.00 41.10  ? 257 LYS B NZ  1 
ATOM   5469  N  N   . ILE B 1 258 ? 20.977  39.596  -3.391  1.00 39.79  ? 258 ILE B N   1 
ATOM   5470  C  CA  . ILE B 1 258 ? 21.211  40.099  -4.742  1.00 35.44  ? 258 ILE B CA  1 
ATOM   5471  C  C   . ILE B 1 258 ? 22.251  39.225  -5.423  1.00 33.20  ? 258 ILE B C   1 
ATOM   5472  O  O   . ILE B 1 258 ? 23.256  38.847  -4.812  1.00 31.94  ? 258 ILE B O   1 
ATOM   5473  C  CB  . ILE B 1 258 ? 21.659  41.578  -4.718  1.00 39.32  ? 258 ILE B CB  1 
ATOM   5474  C  CG1 . ILE B 1 258 ? 20.712  42.437  -3.858  1.00 45.63  ? 258 ILE B CG1 1 
ATOM   5475  C  CG2 . ILE B 1 258 ? 21.704  42.136  -6.129  1.00 37.78  ? 258 ILE B CG2 1 
ATOM   5476  C  CD1 . ILE B 1 258 ? 21.402  43.337  -2.812  1.00 42.26  ? 258 ILE B CD1 1 
ATOM   5477  N  N   . GLY B 1 259 ? 22.001  38.894  -6.692  1.00 32.48  ? 259 GLY B N   1 
ATOM   5478  C  CA  . GLY B 1 259 ? 22.992  38.172  -7.474  1.00 35.96  ? 259 GLY B CA  1 
ATOM   5479  C  C   . GLY B 1 259 ? 24.312  38.920  -7.533  1.00 40.34  ? 259 GLY B C   1 
ATOM   5480  O  O   . GLY B 1 259 ? 24.356  40.150  -7.540  1.00 33.46  ? 259 GLY B O   1 
ATOM   5481  N  N   . VAL B 1 260 ? 25.401  38.161  -7.564  1.00 41.33  ? 260 VAL B N   1 
ATOM   5482  C  CA  . VAL B 1 260 ? 26.746  38.708  -7.434  1.00 45.63  ? 260 VAL B CA  1 
ATOM   5483  C  C   . VAL B 1 260 ? 27.444  38.671  -8.791  1.00 49.94  ? 260 VAL B C   1 
ATOM   5484  O  O   . VAL B 1 260 ? 26.966  38.057  -9.746  1.00 44.16  ? 260 VAL B O   1 
ATOM   5485  C  CB  . VAL B 1 260 ? 27.566  37.942  -6.387  1.00 48.07  ? 260 VAL B CB  1 
ATOM   5486  C  CG1 . VAL B 1 260 ? 26.801  37.865  -5.065  1.00 44.58  ? 260 VAL B CG1 1 
ATOM   5487  C  CG2 . VAL B 1 260 ? 27.894  36.552  -6.930  1.00 47.45  ? 260 VAL B CG2 1 
ATOM   5488  N  N   . VAL B 1 261 ? 28.604  39.326  -8.871  1.00 52.57  ? 261 VAL B N   1 
ATOM   5489  C  CA  . VAL B 1 261 ? 29.342  39.334  -10.166 1.00 53.56  ? 261 VAL B CA  1 
ATOM   5490  C  C   . VAL B 1 261 ? 30.794  38.897  -9.930  1.00 56.86  ? 261 VAL B C   1 
ATOM   5491  O  O   . VAL B 1 261 ? 31.558  38.859  -10.909 1.00 45.06  ? 261 VAL B O   1 
ATOM   5492  C  CB  . VAL B 1 261 ? 29.238  40.719  -10.831 1.00 54.73  ? 261 VAL B CB  1 
ATOM   5493  C  CG1 . VAL B 1 261 ? 27.953  40.880  -11.626 1.00 44.94  ? 261 VAL B CG1 1 
ATOM   5494  C  CG2 . VAL B 1 261 ? 29.381  41.844  -9.819  1.00 49.92  ? 261 VAL B CG2 1 
ATOM   5495  N  N   . SER B 1 262 ? 31.133  38.520  -8.691  1.00 60.44  ? 262 SER B N   1 
ATOM   5496  C  CA  . SER B 1 262 ? 32.551  38.226  -8.360  1.00 64.83  ? 262 SER B CA  1 
ATOM   5497  C  C   . SER B 1 262 ? 32.705  37.341  -7.118  1.00 65.45  ? 262 SER B C   1 
ATOM   5498  O  O   . SER B 1 262 ? 31.703  37.108  -6.429  1.00 58.34  ? 262 SER B O   1 
ATOM   5499  C  CB  . SER B 1 262 ? 33.310  39.514  -8.159  1.00 61.46  ? 262 SER B CB  1 
ATOM   5500  O  OG  . SER B 1 262 ? 32.982  40.100  -6.907  1.00 58.79  ? 262 SER B OG  1 
ATOM   5501  N  N   . SER B 1 263 ? 33.942  36.924  -6.829  1.00 63.97  ? 263 SER B N   1 
ATOM   5502  C  CA  . SER B 1 263 ? 34.250  36.028  -5.687  1.00 60.15  ? 263 SER B CA  1 
ATOM   5503  C  C   . SER B 1 263 ? 34.226  36.678  -4.302  1.00 65.94  ? 263 SER B C   1 
ATOM   5504  O  O   . SER B 1 263 ? 33.935  35.971  -3.324  1.00 62.67  ? 263 SER B O   1 
ATOM   5505  C  CB  . SER B 1 263 ? 35.661  35.554  -5.813  1.00 58.74  ? 263 SER B CB  1 
ATOM   5506  O  OG  . SER B 1 263 ? 36.572  36.609  -5.551  1.00 62.21  ? 263 SER B OG  1 
ATOM   5507  N  N   . ASP B 1 264 ? 34.498  37.981  -4.233  1.00 63.91  ? 264 ASP B N   1 
ATOM   5508  C  CA  . ASP B 1 264 ? 34.299  38.759  -2.983  1.00 61.75  ? 264 ASP B CA  1 
ATOM   5509  C  C   . ASP B 1 264 ? 32.799  39.056  -2.885  1.00 62.41  ? 264 ASP B C   1 
ATOM   5510  O  O   . ASP B 1 264 ? 32.419  39.870  -2.036  1.00 60.84  ? 264 ASP B O   1 
ATOM   5511  C  CB  . ASP B 1 264 ? 35.248  39.962  -2.931  1.00 56.98  ? 264 ASP B CB  1 
ATOM   5512  C  CG  . ASP B 1 264 ? 34.909  41.042  -3.938  1.00 62.82  ? 264 ASP B CG  1 
ATOM   5513  O  OD1 . ASP B 1 264 ? 34.084  40.772  -4.826  1.00 68.01  ? 264 ASP B OD1 1 
ATOM   5514  O  OD2 . ASP B 1 264 ? 35.473  42.140  -3.822  1.00 65.75  ? 264 ASP B OD2 1 
ATOM   5515  N  N   . LEU B 1 265 ? 31.998  38.453  -3.770  1.00 60.87  ? 265 LEU B N   1 
ATOM   5516  C  CA  . LEU B 1 265 ? 30.520  38.562  -3.696  1.00 56.24  ? 265 LEU B CA  1 
ATOM   5517  C  C   . LEU B 1 265 ? 30.085  40.017  -3.801  1.00 54.14  ? 265 LEU B C   1 
ATOM   5518  O  O   . LEU B 1 265 ? 29.240  40.429  -2.996  1.00 52.84  ? 265 LEU B O   1 
ATOM   5519  C  CB  . LEU B 1 265 ? 30.040  37.928  -2.392  1.00 57.30  ? 265 LEU B CB  1 
ATOM   5520  C  CG  . LEU B 1 265 ? 29.324  36.585  -2.520  1.00 54.50  ? 265 LEU B CG  1 
ATOM   5521  C  CD1 . LEU B 1 265 ? 30.216  35.563  -3.203  1.00 54.22  ? 265 LEU B CD1 1 
ATOM   5522  C  CD2 . LEU B 1 265 ? 28.890  36.079  -1.154  1.00 44.76  ? 265 LEU B CD2 1 
ATOM   5523  N  N   . ILE B 1 266 ? 30.634  40.739  -4.766  1.00 53.08  ? 266 ILE B N   1 
ATOM   5524  C  CA  . ILE B 1 266 ? 30.150  42.124  -5.010  1.00 55.77  ? 266 ILE B CA  1 
ATOM   5525  C  C   . ILE B 1 266 ? 28.794  42.014  -5.699  1.00 47.23  ? 266 ILE B C   1 
ATOM   5526  O  O   . ILE B 1 266 ? 28.703  41.361  -6.743  1.00 47.50  ? 266 ILE B O   1 
ATOM   5527  C  CB  . ILE B 1 266 ? 31.149  42.943  -5.843  1.00 51.09  ? 266 ILE B CB  1 
ATOM   5528  C  CG1 . ILE B 1 266 ? 32.289  43.473  -4.969  1.00 55.20  ? 266 ILE B CG1 1 
ATOM   5529  C  CG2 . ILE B 1 266 ? 30.445  44.065  -6.585  1.00 53.61  ? 266 ILE B CG2 1 
ATOM   5530  C  CD1 . ILE B 1 266 ? 33.494  43.941  -5.748  1.00 54.70  ? 266 ILE B CD1 1 
ATOM   5531  N  N   . PRO B 1 267 ? 27.741  42.612  -5.124  1.00 45.47  ? 267 PRO B N   1 
ATOM   5532  C  CA  . PRO B 1 267 ? 26.420  42.570  -5.755  1.00 45.72  ? 267 PRO B CA  1 
ATOM   5533  C  C   . PRO B 1 267 ? 26.451  43.124  -7.174  1.00 51.36  ? 267 PRO B C   1 
ATOM   5534  O  O   . PRO B 1 267 ? 27.323  43.914  -7.547  1.00 48.92  ? 267 PRO B O   1 
ATOM   5535  C  CB  . PRO B 1 267 ? 25.558  43.441  -4.829  1.00 45.89  ? 267 PRO B CB  1 
ATOM   5536  C  CG  . PRO B 1 267 ? 26.244  43.380  -3.512  1.00 43.03  ? 267 PRO B CG  1 
ATOM   5537  C  CD  . PRO B 1 267 ? 27.708  43.286  -3.811  1.00 41.72  ? 267 PRO B CD  1 
ATOM   5538  N  N   . HIS B 1 268 ? 25.487  42.679  -7.974  1.00 48.62  ? 268 HIS B N   1 
ATOM   5539  C  CA  . HIS B 1 268 ? 25.270  43.180  -9.321  1.00 41.70  ? 268 HIS B CA  1 
ATOM   5540  C  C   . HIS B 1 268 ? 25.152  44.699  -9.317  1.00 45.73  ? 268 HIS B C   1 
ATOM   5541  O  O   . HIS B 1 268 ? 24.615  45.271  -8.357  1.00 46.73  ? 268 HIS B O   1 
ATOM   5542  C  CB  . HIS B 1 268 ? 24.013  42.556  -9.908  1.00 40.46  ? 268 HIS B CB  1 
ATOM   5543  C  CG  . HIS B 1 268 ? 23.875  42.752  -11.386 1.00 43.78  ? 268 HIS B CG  1 
ATOM   5544  N  ND1 . HIS B 1 268 ? 22.965  43.625  -11.939 1.00 46.14  ? 268 HIS B ND1 1 
ATOM   5545  C  CD2 . HIS B 1 268 ? 24.528  42.182  -12.425 1.00 44.33  ? 268 HIS B CD2 1 
ATOM   5546  C  CE1 . HIS B 1 268 ? 23.055  43.578  -13.255 1.00 43.90  ? 268 HIS B CE1 1 
ATOM   5547  N  NE2 . HIS B 1 268 ? 24.001  42.714  -13.576 1.00 48.21  ? 268 HIS B NE2 1 
ATOM   5548  N  N   . PRO B 1 269 ? 25.651  45.385  -10.358 1.00 44.57  ? 269 PRO B N   1 
ATOM   5549  C  CA  . PRO B 1 269 ? 25.585  46.854  -10.380 1.00 40.78  ? 269 PRO B CA  1 
ATOM   5550  C  C   . PRO B 1 269 ? 24.207  47.428  -10.120 1.00 41.49  ? 269 PRO B C   1 
ATOM   5551  O  O   . PRO B 1 269 ? 24.105  48.514  -9.527  1.00 37.84  ? 269 PRO B O   1 
ATOM   5552  C  CB  . PRO B 1 269 ? 26.068  47.193  -11.796 1.00 38.62  ? 269 PRO B CB  1 
ATOM   5553  C  CG  . PRO B 1 269 ? 27.034  46.120  -12.100 1.00 44.98  ? 269 PRO B CG  1 
ATOM   5554  C  CD  . PRO B 1 269 ? 26.498  44.865  -11.446 1.00 43.58  ? 269 PRO B CD  1 
ATOM   5555  N  N   . ILE B 1 270 ? 23.134  46.742  -10.525 1.00 36.32  ? 270 ILE B N   1 
ATOM   5556  C  CA  . ILE B 1 270 ? 21.820  47.353  -10.364 1.00 41.22  ? 270 ILE B CA  1 
ATOM   5557  C  C   . ILE B 1 270 ? 21.374  47.429  -8.918  1.00 33.13  ? 270 ILE B C   1 
ATOM   5558  O  O   . ILE B 1 270 ? 20.367  48.085  -8.634  1.00 39.50  ? 270 ILE B O   1 
ATOM   5559  C  CB  . ILE B 1 270 ? 20.729  46.620  -11.166 1.00 37.52  ? 270 ILE B CB  1 
ATOM   5560  C  CG1 . ILE B 1 270 ? 20.524  45.211  -10.622 1.00 35.74  ? 270 ILE B CG1 1 
ATOM   5561  C  CG2 . ILE B 1 270 ? 21.066  46.632  -12.647 1.00 35.86  ? 270 ILE B CG2 1 
ATOM   5562  C  CD1 . ILE B 1 270 ? 19.503  44.438  -11.397 1.00 35.91  ? 270 ILE B CD1 1 
ATOM   5563  N  N   . TRP B 1 271 ? 22.099  46.794  -8.000  1.00 35.26  ? 271 TRP B N   1 
ATOM   5564  C  CA  . TRP B 1 271 ? 21.613  46.683  -6.626  1.00 37.96  ? 271 TRP B CA  1 
ATOM   5565  C  C   . TRP B 1 271 ? 21.324  48.054  -6.028  1.00 39.02  ? 271 TRP B C   1 
ATOM   5566  O  O   . TRP B 1 271 ? 20.345  48.225  -5.291  1.00 33.86  ? 271 TRP B O   1 
ATOM   5567  C  CB  . TRP B 1 271 ? 22.619  45.904  -5.766  1.00 40.05  ? 271 TRP B CB  1 
ATOM   5568  C  CG  . TRP B 1 271 ? 23.548  46.788  -5.029  1.00 42.90  ? 271 TRP B CG  1 
ATOM   5569  C  CD1 . TRP B 1 271 ? 24.785  47.186  -5.433  1.00 46.04  ? 271 TRP B CD1 1 
ATOM   5570  C  CD2 . TRP B 1 271 ? 23.306  47.431  -3.776  1.00 41.43  ? 271 TRP B CD2 1 
ATOM   5571  N  NE1 . TRP B 1 271 ? 25.339  48.025  -4.501  1.00 45.81  ? 271 TRP B NE1 1 
ATOM   5572  C  CE2 . TRP B 1 271 ? 24.447  48.203  -3.477  1.00 44.93  ? 271 TRP B CE2 1 
ATOM   5573  C  CE3 . TRP B 1 271 ? 22.238  47.432  -2.879  1.00 45.43  ? 271 TRP B CE3 1 
ATOM   5574  C  CZ2 . TRP B 1 271 ? 24.556  48.967  -2.305  1.00 41.71  ? 271 TRP B CZ2 1 
ATOM   5575  C  CZ3 . TRP B 1 271 ? 22.343  48.190  -1.718  1.00 50.05  ? 271 TRP B CZ3 1 
ATOM   5576  C  CH2 . TRP B 1 271 ? 23.497  48.956  -1.448  1.00 43.15  ? 271 TRP B CH2 1 
ATOM   5577  N  N   . THR B 1 272 ? 22.139  49.060  -6.358  1.00 40.42  ? 272 THR B N   1 
ATOM   5578  C  CA  . THR B 1 272 ? 21.968  50.357  -5.704  1.00 33.17  ? 272 THR B CA  1 
ATOM   5579  C  C   . THR B 1 272 ? 20.672  51.033  -6.132  1.00 30.21  ? 272 THR B C   1 
ATOM   5580  O  O   . THR B 1 272 ? 19.940  51.567  -5.295  1.00 38.55  ? 272 THR B O   1 
ATOM   5581  C  CB  . THR B 1 272 ? 23.168  51.261  -5.987  1.00 35.75  ? 272 THR B CB  1 
ATOM   5582  O  OG1 . THR B 1 272 ? 24.365  50.628  -5.521  1.00 33.17  ? 272 THR B OG1 1 
ATOM   5583  C  CG2 . THR B 1 272 ? 23.000  52.586  -5.262  1.00 37.45  ? 272 THR B CG2 1 
ATOM   5584  N  N   . GLU B 1 273 ? 20.355  51.008  -7.420  1.00 30.89  ? 273 GLU B N   1 
ATOM   5585  C  CA  . GLU B 1 273 ? 19.130  51.654  -7.863  1.00 35.14  ? 273 GLU B CA  1 
ATOM   5586  C  C   . GLU B 1 273 ? 17.906  50.833  -7.502  1.00 35.11  ? 273 GLU B C   1 
ATOM   5587  O  O   . GLU B 1 273 ? 16.831  51.398  -7.263  1.00 37.45  ? 273 GLU B O   1 
ATOM   5588  C  CB  . GLU B 1 273 ? 19.144  51.888  -9.379  1.00 37.55  ? 273 GLU B CB  1 
ATOM   5589  C  CG  . GLU B 1 273 ? 20.379  52.603  -9.941  1.00 41.03  ? 273 GLU B CG  1 
ATOM   5590  C  CD  . GLU B 1 273 ? 21.444  51.620  -10.447 1.00 49.90  ? 273 GLU B CD  1 
ATOM   5591  O  OE1 . GLU B 1 273 ? 21.969  50.809  -9.636  1.00 44.62  ? 273 GLU B OE1 1 
ATOM   5592  O  OE2 . GLU B 1 273 ? 21.717  51.625  -11.671 1.00 50.74  ? 273 GLU B OE2 1 
ATOM   5593  N  N   . VAL B 1 274 ? 18.034  49.505  -7.496  1.00 40.68  ? 274 VAL B N   1 
ATOM   5594  C  CA  . VAL B 1 274 ? 16.920  48.663  -7.067  1.00 36.37  ? 274 VAL B CA  1 
ATOM   5595  C  C   . VAL B 1 274 ? 16.518  49.019  -5.642  1.00 33.69  ? 274 VAL B C   1 
ATOM   5596  O  O   . VAL B 1 274 ? 15.335  49.230  -5.343  1.00 36.17  ? 274 VAL B O   1 
ATOM   5597  C  CB  . VAL B 1 274 ? 17.290  47.177  -7.201  1.00 34.39  ? 274 VAL B CB  1 
ATOM   5598  C  CG1 . VAL B 1 274 ? 16.231  46.307  -6.508  1.00 26.83  ? 274 VAL B CG1 1 
ATOM   5599  C  CG2 . VAL B 1 274 ? 17.464  46.809  -8.664  1.00 30.61  ? 274 VAL B CG2 1 
ATOM   5600  N  N   . VAL B 1 275 ? 17.507  49.129  -4.750  1.00 35.43  ? 275 VAL B N   1 
ATOM   5601  C  CA  . VAL B 1 275 ? 17.239  49.483  -3.357  1.00 35.57  ? 275 VAL B CA  1 
ATOM   5602  C  C   . VAL B 1 275 ? 16.720  50.913  -3.255  1.00 37.49  ? 275 VAL B C   1 
ATOM   5603  O  O   . VAL B 1 275 ? 15.731  51.177  -2.564  1.00 36.29  ? 275 VAL B O   1 
ATOM   5604  C  CB  . VAL B 1 275 ? 18.497  49.294  -2.489  1.00 36.15  ? 275 VAL B CB  1 
ATOM   5605  C  CG1 . VAL B 1 275 ? 18.300  49.979  -1.149  1.00 38.32  ? 275 VAL B CG1 1 
ATOM   5606  C  CG2 . VAL B 1 275 ? 18.827  47.810  -2.286  1.00 38.29  ? 275 VAL B CG2 1 
ATOM   5607  N  N   . GLU B 1 276 ? 17.393  51.866  -3.916  1.00 36.88  ? 276 GLU B N   1 
ATOM   5608  C  CA  . GLU B 1 276 ? 16.947  53.252  -3.819  1.00 31.38  ? 276 GLU B CA  1 
ATOM   5609  C  C   . GLU B 1 276 ? 15.546  53.409  -4.379  1.00 31.15  ? 276 GLU B C   1 
ATOM   5610  O  O   . GLU B 1 276 ? 14.727  54.137  -3.815  1.00 38.80  ? 276 GLU B O   1 
ATOM   5611  C  CB  . GLU B 1 276 ? 17.927  54.190  -4.525  1.00 42.70  ? 276 GLU B CB  1 
ATOM   5612  C  CG  . GLU B 1 276 ? 18.670  55.126  -3.549  1.00 48.49  ? 276 GLU B CG  1 
ATOM   5613  C  CD  . GLU B 1 276 ? 19.904  55.781  -4.163  1.00 53.18  ? 276 GLU B CD  1 
ATOM   5614  O  OE1 . GLU B 1 276 ? 19.741  56.619  -5.080  1.00 60.55  ? 276 GLU B OE1 1 
ATOM   5615  O  OE2 . GLU B 1 276 ? 21.033  55.465  -3.727  1.00 57.30  ? 276 GLU B OE2 1 
ATOM   5616  N  N   . ALA B 1 277 ? 15.231  52.696  -5.465  1.00 35.11  ? 277 ALA B N   1 
ATOM   5617  C  CA  . ALA B 1 277 ? 13.872  52.712  -5.992  1.00 29.17  ? 277 ALA B CA  1 
ATOM   5618  C  C   . ALA B 1 277 ? 12.866  52.017  -5.072  1.00 35.16  ? 277 ALA B C   1 
ATOM   5619  O  O   . ALA B 1 277 ? 11.658  52.147  -5.295  1.00 32.38  ? 277 ALA B O   1 
ATOM   5620  C  CB  . ALA B 1 277 ? 13.846  52.065  -7.371  1.00 31.52  ? 277 ALA B CB  1 
ATOM   5621  N  N   . SER B 1 278 ? 13.318  51.302  -4.042  1.00 31.08  ? 278 SER B N   1 
ATOM   5622  C  CA  . SER B 1 278 ? 12.409  50.590  -3.157  1.00 36.77  ? 278 SER B CA  1 
ATOM   5623  C  C   . SER B 1 278 ? 12.275  51.179  -1.758  1.00 36.92  ? 278 SER B C   1 
ATOM   5624  O  O   . SER B 1 278 ? 11.409  50.725  -1.004  1.00 38.67  ? 278 SER B O   1 
ATOM   5625  C  CB  . SER B 1 278 ? 12.843  49.124  -3.035  1.00 35.52  ? 278 SER B CB  1 
ATOM   5626  O  OG  . SER B 1 278 ? 12.891  48.524  -4.314  1.00 35.94  ? 278 SER B OG  1 
ATOM   5627  N  N   . LEU B 1 279 ? 13.079  52.170  -1.386  1.00 38.79  ? 279 LEU B N   1 
ATOM   5628  C  CA  . LEU B 1 279 ? 13.051  52.687  -0.016  1.00 39.73  ? 279 LEU B CA  1 
ATOM   5629  C  C   . LEU B 1 279 ? 11.738  53.370  0.370   1.00 38.64  ? 279 LEU B C   1 
ATOM   5630  O  O   . LEU B 1 279 ? 11.270  53.172  1.499   1.00 43.19  ? 279 LEU B O   1 
ATOM   5631  C  CB  . LEU B 1 279 ? 14.219  53.644  0.216   1.00 42.02  ? 279 LEU B CB  1 
ATOM   5632  C  CG  . LEU B 1 279 ? 15.516  52.895  0.489   1.00 43.52  ? 279 LEU B CG  1 
ATOM   5633  C  CD1 . LEU B 1 279 ? 16.676  53.863  0.629   1.00 37.27  ? 279 LEU B CD1 1 
ATOM   5634  C  CD2 . LEU B 1 279 ? 15.371  51.987  1.727   1.00 36.58  ? 279 LEU B CD2 1 
ATOM   5635  N  N   . PRO B 1 280 ? 11.118  54.180  -0.502  1.00 36.17  ? 280 PRO B N   1 
ATOM   5636  C  CA  . PRO B 1 280 ? 9.798   54.739  -0.158  1.00 37.41  ? 280 PRO B CA  1 
ATOM   5637  C  C   . PRO B 1 280 ? 8.754   53.701  0.228   1.00 35.57  ? 280 PRO B C   1 
ATOM   5638  O  O   . PRO B 1 280 ? 8.072   53.877  1.245   1.00 41.57  ? 280 PRO B O   1 
ATOM   5639  C  CB  . PRO B 1 280 ? 9.400   55.488  -1.435  1.00 36.04  ? 280 PRO B CB  1 
ATOM   5640  C  CG  . PRO B 1 280 ? 10.670  55.865  -2.040  1.00 42.10  ? 280 PRO B CG  1 
ATOM   5641  C  CD  . PRO B 1 280 ? 11.661  54.799  -1.722  1.00 36.53  ? 280 PRO B CD  1 
ATOM   5642  N  N   . LEU B 1 281 ? 8.600   52.630  -0.557  1.00 33.84  ? 281 LEU B N   1 
ATOM   5643  C  CA  . LEU B 1 281 ? 7.602   51.608  -0.231  1.00 39.20  ? 281 LEU B CA  1 
ATOM   5644  C  C   . LEU B 1 281 ? 7.946   50.884  1.069   1.00 27.82  ? 281 LEU B C   1 
ATOM   5645  O  O   . LEU B 1 281 ? 7.055   50.585  1.865   1.00 37.38  ? 281 LEU B O   1 
ATOM   5646  C  CB  . LEU B 1 281 ? 7.458   50.600  -1.378  1.00 35.86  ? 281 LEU B CB  1 
ATOM   5647  C  CG  . LEU B 1 281 ? 6.528   49.389  -1.105  1.00 31.64  ? 281 LEU B CG  1 
ATOM   5648  C  CD1 . LEU B 1 281 ? 5.071   49.795  -0.995  1.00 29.39  ? 281 LEU B CD1 1 
ATOM   5649  C  CD2 . LEU B 1 281 ? 6.679   48.294  -2.157  1.00 30.90  ? 281 LEU B CD2 1 
ATOM   5650  N  N   . ALA B 1 282 ? 9.226   50.600  1.310   1.00 36.27  ? 282 ALA B N   1 
ATOM   5651  C  CA  . ALA B 1 282 ? 9.604   50.009  2.589   1.00 41.55  ? 282 ALA B CA  1 
ATOM   5652  C  C   . ALA B 1 282 ? 9.322   50.973  3.729   1.00 40.63  ? 282 ALA B C   1 
ATOM   5653  O  O   . ALA B 1 282 ? 8.941   50.559  4.831   1.00 39.25  ? 282 ALA B O   1 
ATOM   5654  C  CB  . ALA B 1 282 ? 11.079  49.604  2.589   1.00 39.52  ? 282 ALA B CB  1 
ATOM   5655  N  N   . GLU B 1 283 ? 9.494   52.266  3.478   1.00 38.43  ? 283 GLU B N   1 
ATOM   5656  C  CA  . GLU B 1 283 ? 9.093   53.267  4.458   1.00 44.47  ? 283 GLU B CA  1 
ATOM   5657  C  C   . GLU B 1 283 ? 7.575   53.305  4.626   1.00 43.46  ? 283 GLU B C   1 
ATOM   5658  O  O   . GLU B 1 283 ? 7.070   53.407  5.751   1.00 42.48  ? 283 GLU B O   1 
ATOM   5659  C  CB  . GLU B 1 283 ? 9.616   54.637  4.031   1.00 42.26  ? 283 GLU B CB  1 
ATOM   5660  C  CG  . GLU B 1 283 ? 9.397   55.740  5.043   1.00 46.85  ? 283 GLU B CG  1 
ATOM   5661  C  CD  . GLU B 1 283 ? 10.035  57.035  4.595   1.00 57.86  ? 283 GLU B CD  1 
ATOM   5662  O  OE1 . GLU B 1 283 ? 9.684   58.102  5.144   1.00 70.68  ? 283 GLU B OE1 1 
ATOM   5663  O  OE2 . GLU B 1 283 ? 10.881  56.979  3.677   1.00 64.53  ? 283 GLU B OE2 1 
ATOM   5664  N  N   . GLU B 1 284 ? 6.830   53.249  3.519   1.00 39.21  ? 284 GLU B N   1 
ATOM   5665  C  CA  . GLU B 1 284 ? 5.378   53.309  3.620   1.00 39.75  ? 284 GLU B CA  1 
ATOM   5666  C  C   . GLU B 1 284 ? 4.814   52.068  4.304   1.00 44.26  ? 284 GLU B C   1 
ATOM   5667  O  O   . GLU B 1 284 ? 3.759   52.132  4.949   1.00 41.80  ? 284 GLU B O   1 
ATOM   5668  C  CB  . GLU B 1 284 ? 4.776   53.476  2.229   1.00 38.27  ? 284 GLU B CB  1 
ATOM   5669  C  CG  . GLU B 1 284 ? 3.267   53.481  2.221   1.00 45.84  ? 284 GLU B CG  1 
ATOM   5670  C  CD  . GLU B 1 284 ? 2.695   53.234  0.845   1.00 52.89  ? 284 GLU B CD  1 
ATOM   5671  O  OE1 . GLU B 1 284 ? 2.696   54.177  0.023   1.00 58.67  ? 284 GLU B OE1 1 
ATOM   5672  O  OE2 . GLU B 1 284 ? 2.260   52.090  0.585   1.00 53.47  ? 284 GLU B OE2 1 
ATOM   5673  N  N   . LEU B 1 285 ? 5.498   50.934  4.177   1.00 41.60  ? 285 LEU B N   1 
ATOM   5674  C  CA  . LEU B 1 285 ? 5.058   49.702  4.801   1.00 36.24  ? 285 LEU B CA  1 
ATOM   5675  C  C   . LEU B 1 285 ? 5.672   49.486  6.171   1.00 34.79  ? 285 LEU B C   1 
ATOM   5676  O  O   . LEU B 1 285 ? 5.247   48.573  6.884   1.00 34.18  ? 285 LEU B O   1 
ATOM   5677  C  CB  . LEU B 1 285 ? 5.396   48.521  3.905   1.00 32.07  ? 285 LEU B CB  1 
ATOM   5678  C  CG  . LEU B 1 285 ? 4.683   48.590  2.562   1.00 32.12  ? 285 LEU B CG  1 
ATOM   5679  C  CD1 . LEU B 1 285 ? 4.952   47.341  1.749   1.00 31.06  ? 285 LEU B CD1 1 
ATOM   5680  C  CD2 . LEU B 1 285 ? 3.201   48.810  2.779   1.00 33.73  ? 285 LEU B CD2 1 
ATOM   5681  N  N   . ASP B 1 286 ? 6.647   50.307  6.557   1.00 38.56  ? 286 ASP B N   1 
ATOM   5682  C  CA  . ASP B 1 286 ? 7.383   50.125  7.807   1.00 35.30  ? 286 ASP B CA  1 
ATOM   5683  C  C   . ASP B 1 286 ? 8.030   48.740  7.860   1.00 37.60  ? 286 ASP B C   1 
ATOM   5684  O  O   . ASP B 1 286 ? 7.924   48.013  8.850   1.00 35.00  ? 286 ASP B O   1 
ATOM   5685  C  CB  . ASP B 1 286 ? 6.481   50.367  9.018   1.00 39.24  ? 286 ASP B CB  1 
ATOM   5686  C  CG  . ASP B 1 286 ? 7.263   50.726  10.261  1.00 39.90  ? 286 ASP B CG  1 
ATOM   5687  O  OD1 . ASP B 1 286 ? 8.469   51.030  10.128  1.00 36.65  ? 286 ASP B OD1 1 
ATOM   5688  O  OD2 . ASP B 1 286 ? 6.666   50.705  11.363  1.00 43.12  ? 286 ASP B OD2 1 
ATOM   5689  N  N   . VAL B 1 287 ? 8.706   48.383  6.769   1.00 36.42  ? 287 VAL B N   1 
ATOM   5690  C  CA  . VAL B 1 287 ? 9.515   47.174  6.666   1.00 31.43  ? 287 VAL B CA  1 
ATOM   5691  C  C   . VAL B 1 287 ? 10.947  47.607  6.369   1.00 31.72  ? 287 VAL B C   1 
ATOM   5692  O  O   . VAL B 1 287 ? 11.171  48.441  5.484   1.00 35.34  ? 287 VAL B O   1 
ATOM   5693  C  CB  . VAL B 1 287 ? 8.970   46.241  5.564   1.00 31.80  ? 287 VAL B CB  1 
ATOM   5694  C  CG1 . VAL B 1 287 ? 9.933   45.106  5.251   1.00 28.38  ? 287 VAL B CG1 1 
ATOM   5695  C  CG2 . VAL B 1 287 ? 7.607   45.710  5.961   1.00 25.46  ? 287 VAL B CG2 1 
ATOM   5696  N  N   . ILE B 1 288 ? 11.909  47.061  7.121   1.00 32.62  ? 288 ILE B N   1 
ATOM   5697  C  CA  . ILE B 1 288 ? 13.329  47.366  6.950   1.00 32.37  ? 288 ILE B CA  1 
ATOM   5698  C  C   . ILE B 1 288 ? 13.940  46.430  5.912   1.00 35.45  ? 288 ILE B C   1 
ATOM   5699  O  O   . ILE B 1 288 ? 13.750  45.209  5.972   1.00 31.76  ? 288 ILE B O   1 
ATOM   5700  C  CB  . ILE B 1 288 ? 14.084  47.244  8.286   1.00 31.03  ? 288 ILE B CB  1 
ATOM   5701  C  CG1 . ILE B 1 288 ? 13.604  48.294  9.285   1.00 31.37  ? 288 ILE B CG1 1 
ATOM   5702  C  CG2 . ILE B 1 288 ? 15.582  47.394  8.060   1.00 31.85  ? 288 ILE B CG2 1 
ATOM   5703  C  CD1 . ILE B 1 288 ? 14.330  48.216  10.632  1.00 30.37  ? 288 ILE B CD1 1 
ATOM   5704  N  N   . ILE B 1 289 ? 14.692  47.000  4.977   1.00 31.89  ? 289 ILE B N   1 
ATOM   5705  C  CA  . ILE B 1 289 ? 15.457  46.260  3.981   1.00 32.02  ? 289 ILE B CA  1 
ATOM   5706  C  C   . ILE B 1 289 ? 16.875  46.088  4.516   1.00 39.97  ? 289 ILE B C   1 
ATOM   5707  O  O   . ILE B 1 289 ? 17.626  47.067  4.629   1.00 37.54  ? 289 ILE B O   1 
ATOM   5708  C  CB  . ILE B 1 289 ? 15.481  46.998  2.638   1.00 32.21  ? 289 ILE B CB  1 
ATOM   5709  C  CG1 . ILE B 1 289 ? 14.089  47.104  2.022   1.00 34.08  ? 289 ILE B CG1 1 
ATOM   5710  C  CG2 . ILE B 1 289 ? 16.475  46.367  1.676   1.00 37.22  ? 289 ILE B CG2 1 
ATOM   5711  C  CD1 . ILE B 1 289 ? 14.084  48.011  0.820   1.00 31.73  ? 289 ILE B CD1 1 
ATOM   5712  N  N   . CYS B 1 290 ? 17.271  44.849  4.804   1.00 36.02  ? 290 CYS B N   1 
ATOM   5713  C  CA  . CYS B 1 290 ? 18.600  44.557  5.345   1.00 34.55  ? 290 CYS B CA  1 
ATOM   5714  C  C   . CYS B 1 290 ? 19.317  43.470  4.545   1.00 34.97  ? 290 CYS B C   1 
ATOM   5715  O  O   . CYS B 1 290 ? 19.041  42.273  4.728   1.00 31.29  ? 290 CYS B O   1 
ATOM   5716  C  CB  . CYS B 1 290 ? 18.512  44.156  6.812   1.00 33.55  ? 290 CYS B CB  1 
ATOM   5717  S  SG  . CYS B 1 290 ? 17.249  42.907  7.176   1.00 35.73  ? 290 CYS B SG  1 
ATOM   5718  N  N   . PRO B 1 291 ? 20.263  43.842  3.679   1.00 41.91  ? 291 PRO B N   1 
ATOM   5719  C  CA  . PRO B 1 291 ? 21.107  42.839  3.027   1.00 29.87  ? 291 PRO B CA  1 
ATOM   5720  C  C   . PRO B 1 291 ? 22.016  42.143  4.024   1.00 29.16  ? 291 PRO B C   1 
ATOM   5721  O  O   . PRO B 1 291 ? 22.369  42.679  5.076   1.00 27.48  ? 291 PRO B O   1 
ATOM   5722  C  CB  . PRO B 1 291 ? 21.919  43.659  2.018   1.00 36.56  ? 291 PRO B CB  1 
ATOM   5723  C  CG  . PRO B 1 291 ? 21.916  45.028  2.572   1.00 37.81  ? 291 PRO B CG  1 
ATOM   5724  C  CD  . PRO B 1 291 ? 20.564  45.200  3.200   1.00 32.71  ? 291 PRO B CD  1 
ATOM   5725  N  N   . GLU B 1 292 ? 22.419  40.931  3.652   1.00 30.19  ? 292 GLU B N   1 
ATOM   5726  C  CA  . GLU B 1 292 ? 23.055  39.989  4.561   1.00 36.96  ? 292 GLU B CA  1 
ATOM   5727  C  C   . GLU B 1 292 ? 24.554  39.916  4.296   1.00 29.74  ? 292 GLU B C   1 
ATOM   5728  O  O   . GLU B 1 292 ? 24.978  39.679  3.165   1.00 32.45  ? 292 GLU B O   1 
ATOM   5729  C  CB  . GLU B 1 292 ? 22.409  38.609  4.408   1.00 32.83  ? 292 GLU B CB  1 
ATOM   5730  C  CG  . GLU B 1 292 ? 23.021  37.483  5.220   1.00 37.34  ? 292 GLU B CG  1 
ATOM   5731  C  CD  . GLU B 1 292 ? 22.637  36.102  4.665   1.00 36.89  ? 292 GLU B CD  1 
ATOM   5732  O  OE1 . GLU B 1 292 ? 21.816  36.035  3.723   1.00 38.14  ? 292 GLU B OE1 1 
ATOM   5733  O  OE2 . GLU B 1 292 ? 23.175  35.085  5.143   1.00 34.64  ? 292 GLU B OE2 1 
ATOM   5734  N  N   . ILE B 1 293 ? 25.350  40.096  5.349   1.00 35.03  ? 293 ILE B N   1 
ATOM   5735  C  CA  . ILE B 1 293 ? 26.794  39.881  5.295   1.00 37.10  ? 293 ILE B CA  1 
ATOM   5736  C  C   . ILE B 1 293 ? 27.041  38.399  5.560   1.00 37.98  ? 293 ILE B C   1 
ATOM   5737  O  O   . ILE B 1 293 ? 27.020  37.960  6.711   1.00 34.31  ? 293 ILE B O   1 
ATOM   5738  C  CB  . ILE B 1 293 ? 27.542  40.763  6.300   1.00 36.46  ? 293 ILE B CB  1 
ATOM   5739  C  CG1 . ILE B 1 293 ? 27.014  42.195  6.261   1.00 32.62  ? 293 ILE B CG1 1 
ATOM   5740  C  CG2 . ILE B 1 293 ? 29.031  40.743  6.032   1.00 35.46  ? 293 ILE B CG2 1 
ATOM   5741  C  CD1 . ILE B 1 293 ? 26.983  42.778  4.866   1.00 46.39  ? 293 ILE B CD1 1 
ATOM   5742  N  N   . HIS B 1 294 ? 27.279  37.630  4.492   1.00 36.53  ? 294 HIS B N   1 
ATOM   5743  C  CA  . HIS B 1 294 ? 27.620  36.213  4.580   1.00 43.29  ? 294 HIS B CA  1 
ATOM   5744  C  C   . HIS B 1 294 ? 29.079  35.983  4.190   1.00 40.17  ? 294 HIS B C   1 
ATOM   5745  O  O   . HIS B 1 294 ? 29.601  36.636  3.281   1.00 38.20  ? 294 HIS B O   1 
ATOM   5746  C  CB  . HIS B 1 294 ? 26.731  35.359  3.661   1.00 38.06  ? 294 HIS B CB  1 
ATOM   5747  C  CG  . HIS B 1 294 ? 27.042  33.891  3.719   1.00 47.74  ? 294 HIS B CG  1 
ATOM   5748  N  ND1 . HIS B 1 294 ? 27.638  33.293  4.815   1.00 57.49  ? 294 HIS B ND1 1 
ATOM   5749  C  CD2 . HIS B 1 294 ? 26.882  32.908  2.801   1.00 48.16  ? 294 HIS B CD2 1 
ATOM   5750  C  CE1 . HIS B 1 294 ? 27.802  32.001  4.580   1.00 47.65  ? 294 HIS B CE1 1 
ATOM   5751  N  NE2 . HIS B 1 294 ? 27.356  31.743  3.363   1.00 45.86  ? 294 HIS B NE2 1 
ATOM   5752  N  N   . SER B 1 295 ? 29.720  35.041  4.871   1.00 39.60  ? 295 SER B N   1 
ATOM   5753  C  CA  . SER B 1 295 ? 31.026  34.552  4.458   1.00 39.32  ? 295 SER B CA  1 
ATOM   5754  C  C   . SER B 1 295 ? 30.983  34.166  2.981   1.00 42.58  ? 295 SER B C   1 
ATOM   5755  O  O   . SER B 1 295 ? 30.014  33.535  2.542   1.00 44.14  ? 295 SER B O   1 
ATOM   5756  C  CB  . SER B 1 295 ? 31.420  33.350  5.326   1.00 36.89  ? 295 SER B CB  1 
ATOM   5757  O  OG  . SER B 1 295 ? 32.752  32.927  5.101   1.00 40.85  ? 295 SER B OG  1 
ATOM   5758  N  N   . PRO B 1 296 ? 32.022  34.497  2.181   1.00 44.11  ? 296 PRO B N   1 
ATOM   5759  C  CA  . PRO B 1 296 ? 33.337  35.007  2.585   1.00 43.51  ? 296 PRO B CA  1 
ATOM   5760  C  C   . PRO B 1 296 ? 33.453  36.532  2.681   1.00 41.54  ? 296 PRO B C   1 
ATOM   5761  O  O   . PRO B 1 296 ? 34.569  37.027  2.752   1.00 38.00  ? 296 PRO B O   1 
ATOM   5762  C  CB  . PRO B 1 296 ? 34.250  34.477  1.479   1.00 36.81  ? 296 PRO B CB  1 
ATOM   5763  C  CG  . PRO B 1 296 ? 33.388  34.501  0.259   1.00 42.92  ? 296 PRO B CG  1 
ATOM   5764  C  CD  . PRO B 1 296 ? 31.933  34.386  0.713   1.00 39.25  ? 296 PRO B CD  1 
ATOM   5765  N  N   . THR B 1 297 ? 32.347  37.265  2.703   1.00 38.79  ? 297 THR B N   1 
ATOM   5766  C  CA  . THR B 1 297 ? 32.437  38.707  2.878   1.00 38.51  ? 297 THR B CA  1 
ATOM   5767  C  C   . THR B 1 297 ? 32.634  39.053  4.358   1.00 40.43  ? 297 THR B C   1 
ATOM   5768  O  O   . THR B 1 297 ? 31.762  38.744  5.179   1.00 44.87  ? 297 THR B O   1 
ATOM   5769  C  CB  . THR B 1 297 ? 31.196  39.400  2.336   1.00 36.11  ? 297 THR B CB  1 
ATOM   5770  O  OG1 . THR B 1 297 ? 30.910  38.920  1.018   1.00 34.21  ? 297 THR B OG1 1 
ATOM   5771  C  CG2 . THR B 1 297 ? 31.431  40.912  2.283   1.00 38.98  ? 297 THR B CG2 1 
ATOM   5772  N  N   . PRO B 1 298 ? 33.742  39.685  4.738   1.00 33.47  ? 298 PRO B N   1 
ATOM   5773  C  CA  . PRO B 1 298 ? 33.961  40.043  6.137   1.00 38.50  ? 298 PRO B CA  1 
ATOM   5774  C  C   . PRO B 1 298 ? 33.184  41.313  6.462   1.00 34.29  ? 298 PRO B C   1 
ATOM   5775  O  O   . PRO B 1 298 ? 32.494  41.879  5.614   1.00 34.83  ? 298 PRO B O   1 
ATOM   5776  C  CB  . PRO B 1 298 ? 35.465  40.265  6.181   1.00 38.19  ? 298 PRO B CB  1 
ATOM   5777  C  CG  . PRO B 1 298 ? 35.740  40.880  4.850   1.00 38.65  ? 298 PRO B CG  1 
ATOM   5778  C  CD  . PRO B 1 298 ? 34.829  40.188  3.880   1.00 36.63  ? 298 PRO B CD  1 
ATOM   5779  N  N   . ILE B 1 299 ? 33.303  41.770  7.709   1.00 29.60  ? 299 ILE B N   1 
ATOM   5780  C  CA  . ILE B 1 299 ? 32.714  43.064  8.029   1.00 27.93  ? 299 ILE B CA  1 
ATOM   5781  C  C   . ILE B 1 299 ? 33.471  44.186  7.312   1.00 39.13  ? 299 ILE B C   1 
ATOM   5782  O  O   . ILE B 1 299 ? 32.862  45.151  6.834   1.00 38.15  ? 299 ILE B O   1 
ATOM   5783  C  CB  . ILE B 1 299 ? 32.668  43.271  9.549   1.00 35.13  ? 299 ILE B CB  1 
ATOM   5784  C  CG1 . ILE B 1 299 ? 31.624  42.327  10.163  1.00 39.67  ? 299 ILE B CG1 1 
ATOM   5785  C  CG2 . ILE B 1 299 ? 32.307  44.702  9.882   1.00 37.26  ? 299 ILE B CG2 1 
ATOM   5786  C  CD1 . ILE B 1 299 ? 31.562  42.403  11.659  1.00 29.74  ? 299 ILE B CD1 1 
ATOM   5787  N  N   . LYS B 1 300 ? 34.803  44.054  7.192   1.00 40.86  ? 300 LYS B N   1 
ATOM   5788  C  CA  . LYS B 1 300 ? 35.707  45.080  6.647   1.00 44.29  ? 300 LYS B CA  1 
ATOM   5789  C  C   . LYS B 1 300 ? 35.840  44.915  5.137   1.00 37.53  ? 300 LYS B C   1 
ATOM   5790  O  O   . LYS B 1 300 ? 36.785  44.311  4.640   1.00 39.54  ? 300 LYS B O   1 
ATOM   5791  C  CB  . LYS B 1 300 ? 37.079  44.979  7.301   1.00 44.00  ? 300 LYS B CB  1 
ATOM   5792  C  CG  . LYS B 1 300 ? 37.145  45.435  8.743   1.00 50.23  ? 300 LYS B CG  1 
ATOM   5793  C  CD  . LYS B 1 300 ? 38.542  45.224  9.302   1.00 41.26  ? 300 LYS B CD  1 
ATOM   5794  C  CE  . LYS B 1 300 ? 38.704  45.973  10.614  1.00 53.07  ? 300 LYS B CE  1 
ATOM   5795  N  NZ  . LYS B 1 300 ? 39.762  45.399  11.493  1.00 52.96  ? 300 LYS B NZ  1 
ATOM   5796  N  N   . HIS B 1 301 ? 34.910  45.490  4.391   1.00 36.05  ? 301 HIS B N   1 
ATOM   5797  C  CA  . HIS B 1 301 ? 34.858  45.208  2.968   1.00 42.02  ? 301 HIS B CA  1 
ATOM   5798  C  C   . HIS B 1 301 ? 34.051  46.304  2.301   1.00 41.15  ? 301 HIS B C   1 
ATOM   5799  O  O   . HIS B 1 301 ? 33.169  46.901  2.921   1.00 40.73  ? 301 HIS B O   1 
ATOM   5800  C  CB  . HIS B 1 301 ? 34.226  43.831  2.716   1.00 41.88  ? 301 HIS B CB  1 
ATOM   5801  C  CG  . HIS B 1 301 ? 34.400  43.325  1.321   1.00 41.72  ? 301 HIS B CG  1 
ATOM   5802  N  ND1 . HIS B 1 301 ? 33.540  43.656  0.296   1.00 40.34  ? 301 HIS B ND1 1 
ATOM   5803  C  CD2 . HIS B 1 301 ? 35.318  42.486  0.785   1.00 44.13  ? 301 HIS B CD2 1 
ATOM   5804  C  CE1 . HIS B 1 301 ? 33.930  43.062  -0.816  1.00 44.11  ? 301 HIS B CE1 1 
ATOM   5805  N  NE2 . HIS B 1 301 ? 35.006  42.344  -0.546  1.00 51.55  ? 301 HIS B NE2 1 
ATOM   5806  N  N   . GLU B 1 302 ? 34.350  46.558  1.028   1.00 40.57  ? 302 GLU B N   1 
ATOM   5807  C  CA  . GLU B 1 302 ? 33.634  47.624  0.338   1.00 46.82  ? 302 GLU B CA  1 
ATOM   5808  C  C   . GLU B 1 302 ? 32.133  47.362  0.334   1.00 46.80  ? 302 GLU B C   1 
ATOM   5809  O  O   . GLU B 1 302 ? 31.336  48.305  0.410   1.00 43.57  ? 302 GLU B O   1 
ATOM   5810  C  CB  . GLU B 1 302 ? 34.165  47.793  -1.096  1.00 49.03  ? 302 GLU B CB  1 
ATOM   5811  C  CG  . GLU B 1 302 ? 34.265  46.505  -1.908  1.00 45.16  ? 302 GLU B CG  1 
ATOM   5812  C  CD  . GLU B 1 302 ? 35.660  45.869  -1.855  1.00 55.20  ? 302 GLU B CD  1 
ATOM   5813  O  OE1 . GLU B 1 302 ? 36.187  45.643  -0.733  1.00 53.85  ? 302 GLU B OE1 1 
ATOM   5814  O  OE2 . GLU B 1 302 ? 36.211  45.560  -2.938  1.00 58.88  ? 302 GLU B OE2 1 
ATOM   5815  N  N   . VAL B 1 303 ? 31.733  46.088  0.278   1.00 45.76  ? 303 VAL B N   1 
ATOM   5816  C  CA  . VAL B 1 303 ? 30.312  45.751  0.252   1.00 42.03  ? 303 VAL B CA  1 
ATOM   5817  C  C   . VAL B 1 303 ? 29.614  46.321  1.477   1.00 38.89  ? 303 VAL B C   1 
ATOM   5818  O  O   . VAL B 1 303 ? 28.551  46.945  1.375   1.00 40.47  ? 303 VAL B O   1 
ATOM   5819  C  CB  . VAL B 1 303 ? 30.127  44.227  0.153   1.00 43.44  ? 303 VAL B CB  1 
ATOM   5820  C  CG1 . VAL B 1 303 ? 28.678  43.845  0.439   1.00 41.93  ? 303 VAL B CG1 1 
ATOM   5821  C  CG2 . VAL B 1 303 ? 30.548  43.741  -1.216  1.00 46.39  ? 303 VAL B CG2 1 
ATOM   5822  N  N   . VAL B 1 304 ? 30.211  46.124  2.653   1.00 38.24  ? 304 VAL B N   1 
ATOM   5823  C  CA  . VAL B 1 304 ? 29.635  46.678  3.872   1.00 44.27  ? 304 VAL B CA  1 
ATOM   5824  C  C   . VAL B 1 304 ? 29.714  48.199  3.857   1.00 41.67  ? 304 VAL B C   1 
ATOM   5825  O  O   . VAL B 1 304 ? 28.763  48.888  4.253   1.00 42.73  ? 304 VAL B O   1 
ATOM   5826  C  CB  . VAL B 1 304 ? 30.333  46.085  5.113   1.00 44.08  ? 304 VAL B CB  1 
ATOM   5827  C  CG1 . VAL B 1 304 ? 29.870  46.796  6.384   1.00 44.16  ? 304 VAL B CG1 1 
ATOM   5828  C  CG2 . VAL B 1 304 ? 30.066  44.591  5.211   1.00 39.40  ? 304 VAL B CG2 1 
ATOM   5829  N  N   . ASP B 1 305 ? 30.851  48.748  3.405   1.00 46.58  ? 305 ASP B N   1 
ATOM   5830  C  CA  . ASP B 1 305 ? 31.016  50.200  3.355   1.00 42.65  ? 305 ASP B CA  1 
ATOM   5831  C  C   . ASP B 1 305 ? 29.943  50.840  2.491   1.00 42.30  ? 305 ASP B C   1 
ATOM   5832  O  O   . ASP B 1 305 ? 29.305  51.820  2.896   1.00 46.66  ? 305 ASP B O   1 
ATOM   5833  C  CB  . ASP B 1 305 ? 32.408  50.561  2.831   1.00 43.09  ? 305 ASP B CB  1 
ATOM   5834  C  CG  . ASP B 1 305 ? 33.527  49.964  3.679   1.00 47.50  ? 305 ASP B CG  1 
ATOM   5835  O  OD1 . ASP B 1 305 ? 33.424  49.985  4.930   1.00 47.14  ? 305 ASP B OD1 1 
ATOM   5836  O  OD2 . ASP B 1 305 ? 34.509  49.466  3.086   1.00 53.49  ? 305 ASP B OD2 1 
ATOM   5837  N  N   . ASP B 1 306 ? 29.715  50.286  1.298   1.00 41.48  ? 306 ASP B N   1 
ATOM   5838  C  CA  . ASP B 1 306 ? 28.707  50.859  0.412   1.00 42.88  ? 306 ASP B CA  1 
ATOM   5839  C  C   . ASP B 1 306 ? 27.312  50.772  1.012   1.00 43.61  ? 306 ASP B C   1 
ATOM   5840  O  O   . ASP B 1 306 ? 26.485  51.667  0.797   1.00 46.95  ? 306 ASP B O   1 
ATOM   5841  C  CB  . ASP B 1 306 ? 28.759  50.170  -0.947  1.00 43.68  ? 306 ASP B CB  1 
ATOM   5842  C  CG  . ASP B 1 306 ? 29.949  50.614  -1.775  1.00 46.33  ? 306 ASP B CG  1 
ATOM   5843  O  OD1 . ASP B 1 306 ? 30.626  51.586  -1.371  1.00 52.34  ? 306 ASP B OD1 1 
ATOM   5844  O  OD2 . ASP B 1 306 ? 30.215  49.988  -2.826  1.00 53.38  ? 306 ASP B OD2 1 
ATOM   5845  N  N   . TYR B 1 307 ? 27.036  49.712  1.771   1.00 39.84  ? 307 TYR B N   1 
ATOM   5846  C  CA  . TYR B 1 307 ? 25.751  49.599  2.442   1.00 40.06  ? 307 TYR B CA  1 
ATOM   5847  C  C   . TYR B 1 307 ? 25.556  50.747  3.419   1.00 39.39  ? 307 TYR B C   1 
ATOM   5848  O  O   . TYR B 1 307 ? 24.551  51.464  3.367   1.00 36.29  ? 307 TYR B O   1 
ATOM   5849  C  CB  . TYR B 1 307 ? 25.673  48.252  3.162   1.00 40.94  ? 307 TYR B CB  1 
ATOM   5850  C  CG  . TYR B 1 307 ? 25.379  47.101  2.236   1.00 42.53  ? 307 TYR B CG  1 
ATOM   5851  C  CD1 . TYR B 1 307 ? 24.906  47.331  0.954   1.00 40.08  ? 307 TYR B CD1 1 
ATOM   5852  C  CD2 . TYR B 1 307 ? 25.630  45.787  2.621   1.00 42.58  ? 307 TYR B CD2 1 
ATOM   5853  C  CE1 . TYR B 1 307 ? 24.649  46.309  0.105   1.00 40.81  ? 307 TYR B CE1 1 
ATOM   5854  C  CE2 . TYR B 1 307 ? 25.376  44.743  1.763   1.00 34.91  ? 307 TYR B CE2 1 
ATOM   5855  C  CZ  . TYR B 1 307 ? 24.881  45.015  0.511   1.00 40.47  ? 307 TYR B CZ  1 
ATOM   5856  O  OH  . TYR B 1 307 ? 24.621  43.992  -0.362  1.00 48.54  ? 307 TYR B OH  1 
ATOM   5857  N  N   . ILE B 1 308 ? 26.518  50.932  4.322   1.00 41.48  ? 308 ILE B N   1 
ATOM   5858  C  CA  . ILE B 1 308 ? 26.464  52.035  5.276   1.00 42.19  ? 308 ILE B CA  1 
ATOM   5859  C  C   . ILE B 1 308 ? 26.491  53.380  4.561   1.00 47.58  ? 308 ILE B C   1 
ATOM   5860  O  O   . ILE B 1 308 ? 25.869  54.352  5.017   1.00 49.21  ? 308 ILE B O   1 
ATOM   5861  C  CB  . ILE B 1 308 ? 27.616  51.888  6.287   1.00 40.11  ? 308 ILE B CB  1 
ATOM   5862  C  CG1 . ILE B 1 308 ? 27.504  50.517  6.978   1.00 43.44  ? 308 ILE B CG1 1 
ATOM   5863  C  CG2 . ILE B 1 308 ? 27.617  53.049  7.260   1.00 47.10  ? 308 ILE B CG2 1 
ATOM   5864  C  CD1 . ILE B 1 308 ? 28.639  50.164  7.925   1.00 44.82  ? 308 ILE B CD1 1 
ATOM   5865  N  N   . ALA B 1 309 ? 27.176  53.453  3.416   1.00 42.42  ? 309 ALA B N   1 
ATOM   5866  C  CA  . ALA B 1 309 ? 27.179  54.692  2.646   1.00 46.70  ? 309 ALA B CA  1 
ATOM   5867  C  C   . ALA B 1 309 ? 25.799  55.011  2.100   1.00 46.90  ? 309 ALA B C   1 
ATOM   5868  O  O   . ALA B 1 309 ? 25.437  56.187  1.994   1.00 49.26  ? 309 ALA B O   1 
ATOM   5869  C  CB  . ALA B 1 309 ? 28.191  54.608  1.501   1.00 46.63  ? 309 ALA B CB  1 
ATOM   5870  N  N   . LEU B 1 310 ? 25.021  53.984  1.746   1.00 44.31  ? 310 LEU B N   1 
ATOM   5871  C  CA  . LEU B 1 310 ? 23.659  54.205  1.271   1.00 42.00  ? 310 LEU B CA  1 
ATOM   5872  C  C   . LEU B 1 310 ? 22.755  54.757  2.368   1.00 45.13  ? 310 LEU B C   1 
ATOM   5873  O  O   . LEU B 1 310 ? 21.977  55.690  2.124   1.00 45.27  ? 310 LEU B O   1 
ATOM   5874  C  CB  . LEU B 1 310 ? 23.095  52.902  0.702   1.00 44.08  ? 310 LEU B CB  1 
ATOM   5875  C  CG  . LEU B 1 310 ? 21.651  52.903  0.212   1.00 45.97  ? 310 LEU B CG  1 
ATOM   5876  C  CD1 . LEU B 1 310 ? 21.412  54.009  -0.793  1.00 49.19  ? 310 LEU B CD1 1 
ATOM   5877  C  CD2 . LEU B 1 310 ? 21.338  51.557  -0.408  1.00 44.71  ? 310 LEU B CD2 1 
ATOM   5878  N  N   . ILE B 1 311 ? 22.821  54.171  3.571   1.00 46.41  ? 311 ILE B N   1 
ATOM   5879  C  CA  . ILE B 1 311 ? 22.037  54.650  4.708   1.00 40.12  ? 311 ILE B CA  1 
ATOM   5880  C  C   . ILE B 1 311 ? 22.197  56.155  4.861   1.00 49.61  ? 311 ILE B C   1 
ATOM   5881  O  O   . ILE B 1 311 ? 21.229  56.883  5.132   1.00 49.07  ? 311 ILE B O   1 
ATOM   5882  C  CB  . ILE B 1 311 ? 22.474  53.921  5.995   1.00 41.07  ? 311 ILE B CB  1 
ATOM   5883  C  CG1 . ILE B 1 311 ? 21.952  52.491  6.048   1.00 39.60  ? 311 ILE B CG1 1 
ATOM   5884  C  CG2 . ILE B 1 311 ? 21.984  54.664  7.224   1.00 40.37  ? 311 ILE B CG2 1 
ATOM   5885  C  CD1 . ILE B 1 311 ? 22.583  51.685  7.172   1.00 37.03  ? 311 ILE B CD1 1 
ATOM   5886  N  N   . ARG B 1 312 ? 23.424  56.645  4.684   1.00 51.10  ? 312 ARG B N   1 
ATOM   5887  C  CA  . ARG B 1 312 ? 23.759  58.028  5.004   1.00 53.69  ? 312 ARG B CA  1 
ATOM   5888  C  C   . ARG B 1 312 ? 23.434  58.985  3.871   1.00 48.76  ? 312 ARG B C   1 
ATOM   5889  O  O   . ARG B 1 312 ? 22.955  60.095  4.121   1.00 45.61  ? 312 ARG B O   1 
ATOM   5890  C  CB  . ARG B 1 312 ? 25.239  58.134  5.372   1.00 54.49  ? 312 ARG B CB  1 
ATOM   5891  C  CG  . ARG B 1 312 ? 25.472  57.947  6.851   1.00 54.98  ? 312 ARG B CG  1 
ATOM   5892  C  CD  . ARG B 1 312 ? 25.437  59.289  7.544   1.00 59.61  ? 312 ARG B CD  1 
ATOM   5893  N  NE  . ARG B 1 312 ? 26.730  59.958  7.507   1.00 57.06  ? 312 ARG B NE  1 
ATOM   5894  C  CZ  . ARG B 1 312 ? 26.894  61.262  7.674   1.00 61.59  ? 312 ARG B CZ  1 
ATOM   5895  N  NH1 . ARG B 1 312 ? 25.861  62.079  7.820   1.00 64.35  ? 312 ARG B NH1 1 
ATOM   5896  N  NH2 . ARG B 1 312 ? 28.124  61.762  7.692   1.00 65.41  ? 312 ARG B NH2 1 
ATOM   5897  N  N   . ARG B 1 313 ? 23.676  58.568  2.630   1.00 46.66  ? 313 ARG B N   1 
ATOM   5898  C  CA  . ARG B 1 313 ? 23.321  59.408  1.498   1.00 46.40  ? 313 ARG B CA  1 
ATOM   5899  C  C   . ARG B 1 313 ? 21.805  59.550  1.359   1.00 47.67  ? 313 ARG B C   1 
ATOM   5900  O  O   . ARG B 1 313 ? 21.328  60.558  0.826   1.00 46.98  ? 313 ARG B O   1 
ATOM   5901  C  CB  . ARG B 1 313 ? 23.957  58.846  0.223   1.00 44.94  ? 313 ARG B CB  1 
ATOM   5902  C  CG  . ARG B 1 313 ? 23.111  59.022  -1.043  1.00 54.90  ? 313 ARG B CG  1 
ATOM   5903  C  CD  . ARG B 1 313 ? 23.758  58.355  -2.236  1.00 56.16  ? 313 ARG B CD  1 
ATOM   5904  N  NE  . ARG B 1 313 ? 23.432  56.942  -2.370  1.00 45.51  ? 313 ARG B NE  1 
ATOM   5905  C  CZ  . ARG B 1 313 ? 24.302  55.954  -2.205  1.00 51.30  ? 313 ARG B CZ  1 
ATOM   5906  N  NH1 . ARG B 1 313 ? 25.519  56.178  -1.736  1.00 52.18  ? 313 ARG B NH1 1 
ATOM   5907  N  NH2 . ARG B 1 313 ? 23.945  54.712  -2.528  1.00 48.59  ? 313 ARG B NH2 1 
ATOM   5908  N  N   . THR B 1 314 ? 21.030  58.574  1.852   1.00 48.11  ? 314 THR B N   1 
ATOM   5909  C  CA  . THR B 1 314 ? 19.572  58.609  1.747   1.00 40.06  ? 314 THR B CA  1 
ATOM   5910  C  C   . THR B 1 314 ? 18.883  59.114  3.003   1.00 44.86  ? 314 THR B C   1 
ATOM   5911  O  O   . THR B 1 314 ? 17.745  59.593  2.919   1.00 43.03  ? 314 THR B O   1 
ATOM   5912  C  CB  . THR B 1 314 ? 19.009  57.211  1.437   1.00 47.46  ? 314 THR B CB  1 
ATOM   5913  O  OG1 . THR B 1 314 ? 19.540  56.255  2.371   1.00 42.53  ? 314 THR B OG1 1 
ATOM   5914  C  CG2 . THR B 1 314 ? 19.337  56.789  0.012   1.00 48.59  ? 314 THR B CG2 1 
ATOM   5915  N  N   . GLY B 1 315 ? 19.524  58.994  4.159   1.00 41.42  ? 315 GLY B N   1 
ATOM   5916  C  CA  . GLY B 1 315 ? 18.886  59.303  5.414   1.00 40.04  ? 315 GLY B CA  1 
ATOM   5917  C  C   . GLY B 1 315 ? 17.901  58.265  5.902   1.00 42.72  ? 315 GLY B C   1 
ATOM   5918  O  O   . GLY B 1 315 ? 17.362  58.423  7.005   1.00 44.45  ? 315 GLY B O   1 
ATOM   5919  N  N   . THR B 1 316 ? 17.662  57.205  5.133   1.00 43.64  ? 316 THR B N   1 
ATOM   5920  C  CA  . THR B 1 316 ? 16.600  56.263  5.466   1.00 42.86  ? 316 THR B CA  1 
ATOM   5921  C  C   . THR B 1 316 ? 16.821  55.625  6.833   1.00 35.31  ? 316 THR B C   1 
ATOM   5922  O  O   . THR B 1 316 ? 17.952  55.451  7.295   1.00 36.40  ? 316 THR B O   1 
ATOM   5923  C  CB  . THR B 1 316 ? 16.507  55.174  4.397   1.00 40.62  ? 316 THR B CB  1 
ATOM   5924  O  OG1 . THR B 1 316 ? 15.380  54.331  4.668   1.00 44.49  ? 316 THR B OG1 1 
ATOM   5925  C  CG2 . THR B 1 316 ? 17.770  54.331  4.391   1.00 36.22  ? 316 THR B CG2 1 
ATOM   5926  N  N   . LYS B 1 317 ? 15.711  55.296  7.493   1.00 42.65  ? 317 LYS B N   1 
ATOM   5927  C  CA  . LYS B 1 317 ? 15.709  54.414  8.656   1.00 44.31  ? 317 LYS B CA  1 
ATOM   5928  C  C   . LYS B 1 317 ? 15.205  53.017  8.300   1.00 41.26  ? 317 LYS B C   1 
ATOM   5929  O  O   . LYS B 1 317 ? 14.993  52.190  9.188   1.00 33.60  ? 317 LYS B O   1 
ATOM   5930  C  CB  . LYS B 1 317 ? 14.862  55.013  9.785   1.00 39.47  ? 317 LYS B CB  1 
ATOM   5931  C  CG  . LYS B 1 317 ? 15.180  56.451  10.109  1.00 48.59  ? 317 LYS B CG  1 
ATOM   5932  C  CD  . LYS B 1 317 ? 16.657  56.618  10.451  1.00 52.90  ? 317 LYS B CD  1 
ATOM   5933  C  CE  . LYS B 1 317 ? 17.050  58.094  10.559  1.00 56.92  ? 317 LYS B CE  1 
ATOM   5934  N  NZ  . LYS B 1 317 ? 16.172  58.842  11.504  1.00 57.86  ? 317 LYS B NZ  1 
ATOM   5935  N  N   . HIS B 1 318 ? 15.003  52.740  7.020   1.00 40.01  ? 318 HIS B N   1 
ATOM   5936  C  CA  . HIS B 1 318 ? 14.477  51.461  6.572   1.00 34.76  ? 318 HIS B CA  1 
ATOM   5937  C  C   . HIS B 1 318 ? 15.491  50.717  5.723   1.00 35.10  ? 318 HIS B C   1 
ATOM   5938  O  O   . HIS B 1 318 ? 15.136  50.009  4.782   1.00 36.77  ? 318 HIS B O   1 
ATOM   5939  C  CB  . HIS B 1 318 ? 13.169  51.662  5.824   1.00 32.64  ? 318 HIS B CB  1 
ATOM   5940  C  CG  . HIS B 1 318 ? 12.043  52.045  6.718   1.00 38.18  ? 318 HIS B CG  1 
ATOM   5941  N  ND1 . HIS B 1 318 ? 11.843  53.338  7.144   1.00 42.03  ? 318 HIS B ND1 1 
ATOM   5942  C  CD2 . HIS B 1 318 ? 11.079  51.298  7.307   1.00 38.73  ? 318 HIS B CD2 1 
ATOM   5943  C  CE1 . HIS B 1 318 ? 10.790  53.377  7.941   1.00 47.80  ? 318 HIS B CE1 1 
ATOM   5944  N  NE2 . HIS B 1 318 ? 10.308  52.152  8.058   1.00 42.85  ? 318 HIS B NE2 1 
ATOM   5945  N  N   . PHE B 1 319 ? 16.762  50.881  6.048   1.00 34.35  ? 319 PHE B N   1 
ATOM   5946  C  CA  . PHE B 1 319 ? 17.815  50.113  5.419   1.00 34.73  ? 319 PHE B CA  1 
ATOM   5947  C  C   . PHE B 1 319 ? 18.818  49.790  6.505   1.00 33.98  ? 319 PHE B C   1 
ATOM   5948  O  O   . PHE B 1 319 ? 19.152  50.649  7.317   1.00 38.59  ? 319 PHE B O   1 
ATOM   5949  C  CB  . PHE B 1 319 ? 18.477  50.859  4.252   1.00 37.62  ? 319 PHE B CB  1 
ATOM   5950  C  CG  . PHE B 1 319 ? 19.479  50.025  3.503   1.00 36.49  ? 319 PHE B CG  1 
ATOM   5951  C  CD1 . PHE B 1 319 ? 19.058  49.070  2.604   1.00 33.08  ? 319 PHE B CD1 1 
ATOM   5952  C  CD2 . PHE B 1 319 ? 20.836  50.179  3.717   1.00 35.03  ? 319 PHE B CD2 1 
ATOM   5953  C  CE1 . PHE B 1 319 ? 19.967  48.290  1.928   1.00 32.46  ? 319 PHE B CE1 1 
ATOM   5954  C  CE2 . PHE B 1 319 ? 21.750  49.409  3.044   1.00 34.13  ? 319 PHE B CE2 1 
ATOM   5955  C  CZ  . PHE B 1 319 ? 21.322  48.464  2.148   1.00 37.50  ? 319 PHE B CZ  1 
ATOM   5956  N  N   . GLY B 1 320 ? 19.255  48.536  6.549   1.00 36.53  ? 320 GLY B N   1 
ATOM   5957  C  CA  . GLY B 1 320 ? 20.098  48.093  7.635   1.00 33.34  ? 320 GLY B CA  1 
ATOM   5958  C  C   . GLY B 1 320 ? 20.965  46.941  7.190   1.00 30.23  ? 320 GLY B C   1 
ATOM   5959  O  O   . GLY B 1 320 ? 20.915  46.500  6.040   1.00 31.75  ? 320 GLY B O   1 
ATOM   5960  N  N   . LEU B 1 321 ? 21.790  46.480  8.114   1.00 32.30  ? 321 LEU B N   1 
ATOM   5961  C  CA  . LEU B 1 321 ? 22.683  45.360  7.887   1.00 28.32  ? 321 LEU B CA  1 
ATOM   5962  C  C   . LEU B 1 321 ? 22.105  44.130  8.556   1.00 31.01  ? 321 LEU B C   1 
ATOM   5963  O  O   . LEU B 1 321 ? 21.635  44.200  9.693   1.00 25.55  ? 321 LEU B O   1 
ATOM   5964  C  CB  . LEU B 1 321 ? 24.071  45.622  8.463   1.00 34.50  ? 321 LEU B CB  1 
ATOM   5965  C  CG  . LEU B 1 321 ? 24.832  46.823  7.900   1.00 28.60  ? 321 LEU B CG  1 
ATOM   5966  C  CD1 . LEU B 1 321 ? 26.295  46.710  8.287   1.00 36.54  ? 321 LEU B CD1 1 
ATOM   5967  C  CD2 . LEU B 1 321 ? 24.648  46.870  6.410   1.00 31.97  ? 321 LEU B CD2 1 
ATOM   5968  N  N   . LEU B 1 322 ? 22.134  43.010  7.845   1.00 33.32  ? 322 LEU B N   1 
ATOM   5969  C  CA  . LEU B 1 322 ? 21.882  41.714  8.451   1.00 30.23  ? 322 LEU B CA  1 
ATOM   5970  C  C   . LEU B 1 322 ? 23.214  40.990  8.546   1.00 30.38  ? 322 LEU B C   1 
ATOM   5971  O  O   . LEU B 1 322 ? 23.906  40.819  7.542   1.00 33.44  ? 322 LEU B O   1 
ATOM   5972  C  CB  . LEU B 1 322 ? 20.858  40.912  7.649   1.00 29.00  ? 322 LEU B CB  1 
ATOM   5973  C  CG  . LEU B 1 322 ? 20.151  39.829  8.463   1.00 33.64  ? 322 LEU B CG  1 
ATOM   5974  C  CD1 . LEU B 1 322 ? 18.745  39.585  7.953   1.00 35.35  ? 322 LEU B CD1 1 
ATOM   5975  C  CD2 . LEU B 1 322 ? 20.973  38.576  8.366   1.00 34.39  ? 322 LEU B CD2 1 
ATOM   5976  N  N   . LEU B 1 323 ? 23.584  40.586  9.749   1.00 31.13  ? 323 LEU B N   1 
ATOM   5977  C  CA  . LEU B 1 323 ? 24.831  39.878  9.977   1.00 26.71  ? 323 LEU B CA  1 
ATOM   5978  C  C   . LEU B 1 323 ? 24.552  38.390  10.079  1.00 32.15  ? 323 LEU B C   1 
ATOM   5979  O  O   . LEU B 1 323 ? 23.653  37.985  10.816  1.00 32.16  ? 323 LEU B O   1 
ATOM   5980  C  CB  . LEU B 1 323 ? 25.488  40.360  11.264  1.00 32.81  ? 323 LEU B CB  1 
ATOM   5981  C  CG  . LEU B 1 323 ? 26.798  41.127  11.269  1.00 41.31  ? 323 LEU B CG  1 
ATOM   5982  C  CD1 . LEU B 1 323 ? 26.661  42.471  10.562  1.00 37.93  ? 323 LEU B CD1 1 
ATOM   5983  C  CD2 . LEU B 1 323 ? 27.220  41.301  12.721  1.00 33.38  ? 323 LEU B CD2 1 
ATOM   5984  N  N   . ASP B 1 324 ? 25.334  37.586  9.354   1.00 33.60  ? 324 ASP B N   1 
ATOM   5985  C  CA  . ASP B 1 324 ? 25.338  36.129  9.461   1.00 34.85  ? 324 ASP B CA  1 
ATOM   5986  C  C   . ASP B 1 324 ? 26.567  35.705  10.263  1.00 33.03  ? 324 ASP B C   1 
ATOM   5987  O  O   . ASP B 1 324 ? 27.698  35.972  9.844   1.00 33.09  ? 324 ASP B O   1 
ATOM   5988  C  CB  . ASP B 1 324 ? 25.339  35.494  8.064   1.00 34.33  ? 324 ASP B CB  1 
ATOM   5989  C  CG  . ASP B 1 324 ? 25.102  33.967  8.090   1.00 34.28  ? 324 ASP B CG  1 
ATOM   5990  O  OD1 . ASP B 1 324 ? 26.077  33.216  8.283   1.00 32.87  ? 324 ASP B OD1 1 
ATOM   5991  O  OD2 . ASP B 1 324 ? 23.949  33.516  7.893   1.00 33.83  ? 324 ASP B OD2 1 
ATOM   5992  N  N   . THR B 1 325 ? 26.352  35.045  11.411  1.00 27.79  ? 325 THR B N   1 
ATOM   5993  C  CA  . THR B 1 325 ? 27.453  34.744  12.333  1.00 25.67  ? 325 THR B CA  1 
ATOM   5994  C  C   . THR B 1 325 ? 28.457  33.750  11.791  1.00 29.71  ? 325 THR B C   1 
ATOM   5995  O  O   . THR B 1 325 ? 29.439  33.480  12.488  1.00 37.28  ? 325 THR B O   1 
ATOM   5996  C  CB  . THR B 1 325 ? 26.955  34.223  13.692  1.00 29.97  ? 325 THR B CB  1 
ATOM   5997  O  OG1 . THR B 1 325 ? 26.069  33.102  13.509  1.00 30.93  ? 325 THR B OG1 1 
ATOM   5998  C  CG2 . THR B 1 325 ? 26.273  35.333  14.482  1.00 26.44  ? 325 THR B CG2 1 
ATOM   5999  N  N   . GLY B 1 326 ? 28.258  33.190  10.601  1.00 29.06  ? 326 GLY B N   1 
ATOM   6000  C  CA  . GLY B 1 326 ? 29.297  32.361  10.011  1.00 30.32  ? 326 GLY B CA  1 
ATOM   6001  C  C   . GLY B 1 326 ? 30.569  33.126  9.673   1.00 31.96  ? 326 GLY B C   1 
ATOM   6002  O  O   . GLY B 1 326 ? 31.659  32.554  9.686   1.00 34.46  ? 326 GLY B O   1 
ATOM   6003  N  N   . ILE B 1 327 ? 30.460  34.426  9.379   1.00 39.75  ? 327 ILE B N   1 
ATOM   6004  C  CA  . ILE B 1 327 ? 31.660  35.229  9.164   1.00 32.16  ? 327 ILE B CA  1 
ATOM   6005  C  C   . ILE B 1 327 ? 32.606  35.154  10.357  1.00 35.39  ? 327 ILE B C   1 
ATOM   6006  O  O   . ILE B 1 327 ? 33.803  35.397  10.198  1.00 34.68  ? 327 ILE B O   1 
ATOM   6007  C  CB  . ILE B 1 327 ? 31.302  36.697  8.865   1.00 34.62  ? 327 ILE B CB  1 
ATOM   6008  C  CG1 . ILE B 1 327 ? 30.681  37.364  10.095  1.00 36.74  ? 327 ILE B CG1 1 
ATOM   6009  C  CG2 . ILE B 1 327 ? 30.389  36.796  7.671   1.00 36.22  ? 327 ILE B CG2 1 
ATOM   6010  C  CD1 . ILE B 1 327 ? 30.228  38.766  9.848   1.00 37.44  ? 327 ILE B CD1 1 
ATOM   6011  N  N   . PHE B 1 328 ? 32.101  34.808  11.548  1.00 34.21  ? 328 PHE B N   1 
ATOM   6012  C  CA  . PHE B 1 328 ? 32.923  34.628  12.743  1.00 36.39  ? 328 PHE B CA  1 
ATOM   6013  C  C   . PHE B 1 328 ? 33.445  33.210  12.921  1.00 35.01  ? 328 PHE B C   1 
ATOM   6014  O  O   . PHE B 1 328 ? 34.068  32.935  13.952  1.00 37.68  ? 328 PHE B O   1 
ATOM   6015  C  CB  . PHE B 1 328 ? 32.148  35.002  14.013  1.00 37.41  ? 328 PHE B CB  1 
ATOM   6016  C  CG  . PHE B 1 328 ? 31.581  36.386  14.002  1.00 38.58  ? 328 PHE B CG  1 
ATOM   6017  C  CD1 . PHE B 1 328 ? 32.411  37.488  13.910  1.00 39.93  ? 328 PHE B CD1 1 
ATOM   6018  C  CD2 . PHE B 1 328 ? 30.207  36.589  14.097  1.00 30.70  ? 328 PHE B CD2 1 
ATOM   6019  C  CE1 . PHE B 1 328 ? 31.881  38.763  13.900  1.00 35.82  ? 328 PHE B CE1 1 
ATOM   6020  C  CE2 . PHE B 1 328 ? 29.682  37.856  14.081  1.00 35.61  ? 328 PHE B CE2 1 
ATOM   6021  C  CZ  . PHE B 1 328 ? 30.519  38.948  13.981  1.00 33.93  ? 328 PHE B CZ  1 
ATOM   6022  N  N   . GLN B 1 329 ? 33.191  32.304  11.973  1.00 34.30  ? 329 GLN B N   1 
ATOM   6023  C  CA  . GLN B 1 329 ? 33.674  30.926  12.084  1.00 33.38  ? 329 GLN B CA  1 
ATOM   6024  C  C   . GLN B 1 329 ? 35.199  30.899  12.198  1.00 40.73  ? 329 GLN B C   1 
ATOM   6025  O  O   . GLN B 1 329 ? 35.903  31.512  11.389  1.00 37.13  ? 329 GLN B O   1 
ATOM   6026  C  CB  . GLN B 1 329 ? 33.201  30.122  10.864  1.00 32.12  ? 329 GLN B CB  1 
ATOM   6027  C  CG  . GLN B 1 329 ? 33.754  28.707  10.739  1.00 33.19  ? 329 GLN B CG  1 
ATOM   6028  C  CD  . GLN B 1 329 ? 33.428  28.017  9.410   1.00 35.01  ? 329 GLN B CD  1 
ATOM   6029  O  OE1 . GLN B 1 329 ? 32.655  28.521  8.590   1.00 33.68  ? 329 GLN B OE1 1 
ATOM   6030  N  NE2 . GLN B 1 329 ? 34.025  26.847  9.200   1.00 40.32  ? 329 GLN B NE2 1 
ATOM   6031  N  N   . ASP B 1 330 ? 35.714  30.196  13.215  1.00 40.99  ? 330 ASP B N   1 
ATOM   6032  C  CA  . ASP B 1 330 ? 37.155  30.140  13.459  1.00 42.41  ? 330 ASP B CA  1 
ATOM   6033  C  C   . ASP B 1 330 ? 37.721  28.733  13.344  1.00 47.42  ? 330 ASP B C   1 
ATOM   6034  O  O   . ASP B 1 330 ? 38.898  28.526  13.666  1.00 50.17  ? 330 ASP B O   1 
ATOM   6035  C  CB  . ASP B 1 330 ? 37.511  30.726  14.832  1.00 43.25  ? 330 ASP B CB  1 
ATOM   6036  C  CG  . ASP B 1 330 ? 37.182  29.779  15.998  1.00 47.25  ? 330 ASP B CG  1 
ATOM   6037  O  OD1 . ASP B 1 330 ? 36.518  28.736  15.788  1.00 49.89  ? 330 ASP B OD1 1 
ATOM   6038  O  OD2 . ASP B 1 330 ? 37.594  30.084  17.146  1.00 47.90  ? 330 ASP B OD2 1 
ATOM   6039  N  N   . ARG B 1 331 ? 36.915  27.768  12.922  1.00 46.32  ? 331 ARG B N   1 
ATOM   6040  C  CA  . ARG B 1 331 ? 37.318  26.381  12.764  1.00 44.39  ? 331 ARG B CA  1 
ATOM   6041  C  C   . ARG B 1 331 ? 36.651  25.828  11.514  1.00 40.55  ? 331 ARG B C   1 
ATOM   6042  O  O   . ARG B 1 331 ? 35.601  26.322  11.095  1.00 40.49  ? 331 ARG B O   1 
ATOM   6043  C  CB  . ARG B 1 331 ? 36.930  25.537  13.983  1.00 42.74  ? 331 ARG B CB  1 
ATOM   6044  C  CG  . ARG B 1 331 ? 37.981  25.479  15.070  1.00 44.12  ? 331 ARG B CG  1 
ATOM   6045  C  CD  . ARG B 1 331 ? 37.326  25.372  16.425  1.00 41.58  ? 331 ARG B CD  1 
ATOM   6046  N  NE  . ARG B 1 331 ? 36.183  26.270  16.527  1.00 45.52  ? 331 ARG B NE  1 
ATOM   6047  C  CZ  . ARG B 1 331 ? 35.162  26.097  17.358  1.00 42.34  ? 331 ARG B CZ  1 
ATOM   6048  N  NH1 . ARG B 1 331 ? 35.078  25.033  18.140  1.00 39.58  ? 331 ARG B NH1 1 
ATOM   6049  N  NH2 . ARG B 1 331 ? 34.205  27.018  17.409  1.00 42.27  ? 331 ARG B NH2 1 
ATOM   6050  N  N   . PRO B 1 332 ? 37.233  24.801  10.898  1.00 41.63  ? 332 PRO B N   1 
ATOM   6051  C  CA  . PRO B 1 332 ? 36.715  24.325  9.611   1.00 43.79  ? 332 PRO B CA  1 
ATOM   6052  C  C   . PRO B 1 332 ? 35.525  23.382  9.737   1.00 48.44  ? 332 PRO B C   1 
ATOM   6053  O  O   . PRO B 1 332 ? 35.461  22.533  10.628  1.00 50.22  ? 332 PRO B O   1 
ATOM   6054  C  CB  . PRO B 1 332 ? 37.927  23.600  9.012   1.00 46.24  ? 332 PRO B CB  1 
ATOM   6055  C  CG  . PRO B 1 332 ? 38.606  23.041  10.173  1.00 44.63  ? 332 PRO B CG  1 
ATOM   6056  C  CD  . PRO B 1 332 ? 38.485  24.108  11.254  1.00 42.67  ? 332 PRO B CD  1 
ATOM   6057  N  N   . ILE B 1 333 ? 34.578  23.548  8.819   1.00 51.25  ? 333 ILE B N   1 
ATOM   6058  C  CA  . ILE B 1 333 ? 33.563  22.529  8.555   1.00 53.65  ? 333 ILE B CA  1 
ATOM   6059  C  C   . ILE B 1 333 ? 34.274  21.260  8.095   1.00 58.17  ? 333 ILE B C   1 
ATOM   6060  O  O   . ILE B 1 333 ? 35.206  21.334  7.270   1.00 53.66  ? 333 ILE B O   1 
ATOM   6061  C  CB  . ILE B 1 333 ? 32.557  23.048  7.499   1.00 49.25  ? 333 ILE B CB  1 
ATOM   6062  C  CG1 . ILE B 1 333 ? 31.710  24.181  8.061   1.00 37.81  ? 333 ILE B CG1 1 
ATOM   6063  C  CG2 . ILE B 1 333 ? 31.611  21.988  6.936   1.00 52.73  ? 333 ILE B CG2 1 
ATOM   6064  C  CD1 . ILE B 1 333 ? 31.071  25.034  6.959   1.00 37.38  ? 333 ILE B CD1 1 
ATOM   6065  N  N   . PRO B 1 334 ? 33.911  20.075  8.580   1.00 64.37  ? 334 PRO B N   1 
ATOM   6066  C  CA  . PRO B 1 334 ? 34.663  18.874  8.194   1.00 62.71  ? 334 PRO B CA  1 
ATOM   6067  C  C   . PRO B 1 334 ? 34.488  18.517  6.720   1.00 71.13  ? 334 PRO B C   1 
ATOM   6068  O  O   . PRO B 1 334 ? 33.591  19.013  6.035   1.00 69.24  ? 334 PRO B O   1 
ATOM   6069  C  CB  . PRO B 1 334 ? 34.106  17.786  9.143   1.00 65.56  ? 334 PRO B CB  1 
ATOM   6070  C  CG  . PRO B 1 334 ? 32.876  18.480  9.847   1.00 59.30  ? 334 PRO B CG  1 
ATOM   6071  C  CD  . PRO B 1 334 ? 32.566  19.617  8.938   1.00 60.72  ? 334 PRO B CD  1 
ATOM   6072  N  N   . LEU B 1 335 ? 35.431  17.720  6.211   1.00 75.11  ? 335 LEU B N   1 
ATOM   6073  C  CA  . LEU B 1 335 ? 35.374  17.330  4.814   1.00 79.69  ? 335 LEU B CA  1 
ATOM   6074  C  C   . LEU B 1 335 ? 34.204  16.384  4.628   1.00 83.11  ? 335 LEU B C   1 
ATOM   6075  O  O   . LEU B 1 335 ? 34.070  15.398  5.359   1.00 84.59  ? 335 LEU B O   1 
ATOM   6076  C  CB  . LEU B 1 335 ? 36.691  16.694  4.354   1.00 79.81  ? 335 LEU B CB  1 
ATOM   6077  C  CG  . LEU B 1 335 ? 37.712  17.744  3.901   1.00 78.42  ? 335 LEU B CG  1 
ATOM   6078  C  CD1 . LEU B 1 335 ? 39.057  17.108  3.648   1.00 77.86  ? 335 LEU B CD1 1 
ATOM   6079  C  CD2 . LEU B 1 335 ? 37.235  18.523  2.672   1.00 80.41  ? 335 LEU B CD2 1 
ATOM   6080  N  N   . LYS B 1 336 ? 33.309  16.739  3.702   1.00 88.45  ? 336 LYS B N   1 
ATOM   6081  C  CA  . LYS B 1 336 ? 32.155  15.903  3.413   1.00 91.06  ? 336 LYS B CA  1 
ATOM   6082  C  C   . LYS B 1 336 ? 32.624  14.526  2.941   1.00 93.44  ? 336 LYS B C   1 
ATOM   6083  O  O   . LYS B 1 336 ? 33.751  14.381  2.452   1.00 91.90  ? 336 LYS B O   1 
ATOM   6084  C  CB  . LYS B 1 336 ? 31.269  16.558  2.351   1.00 87.51  ? 336 LYS B CB  1 
ATOM   6085  C  CG  . LYS B 1 336 ? 30.628  17.871  2.792   1.00 81.56  ? 336 LYS B CG  1 
ATOM   6086  C  CD  . LYS B 1 336 ? 29.120  17.870  2.588   1.00 68.27  ? 336 LYS B CD  1 
ATOM   6087  C  CE  . LYS B 1 336 ? 28.647  19.235  2.123   1.00 68.50  ? 336 LYS B CE  1 
ATOM   6088  N  NZ  . LYS B 1 336 ? 27.168  19.288  1.982   1.00 71.05  ? 336 LYS B NZ  1 
ATOM   6089  N  N   . PRO B 1 337 ? 31.784  13.483  3.102   1.00 98.82  ? 337 PRO B N   1 
ATOM   6090  C  CA  . PRO B 1 337 ? 32.200  12.125  2.706   1.00 96.95  ? 337 PRO B CA  1 
ATOM   6091  C  C   . PRO B 1 337 ? 32.706  12.031  1.271   1.00 95.09  ? 337 PRO B C   1 
ATOM   6092  O  O   . PRO B 1 337 ? 31.947  12.229  0.314   1.00 89.65  ? 337 PRO B O   1 
ATOM   6093  C  CB  . PRO B 1 337 ? 30.922  11.299  2.904   1.00 94.97  ? 337 PRO B CB  1 
ATOM   6094  C  CG  . PRO B 1 337 ? 30.174  12.026  3.981   1.00 92.95  ? 337 PRO B CG  1 
ATOM   6095  C  CD  . PRO B 1 337 ? 30.457  13.489  3.752   1.00 93.90  ? 337 PRO B CD  1 
ATOM   6096  N  N   . GLY B 1 338 ? 34.003  11.744  1.123   1.00 94.46  ? 338 GLY B N   1 
ATOM   6097  C  CA  . GLY B 1 338 ? 34.622  11.541  -0.171  1.00 92.57  ? 338 GLY B CA  1 
ATOM   6098  C  C   . GLY B 1 338 ? 35.318  12.746  -0.769  1.00 94.05  ? 338 GLY B C   1 
ATOM   6099  O  O   . GLY B 1 338 ? 35.942  12.610  -1.831  1.00 92.19  ? 338 GLY B O   1 
ATOM   6100  N  N   . GLU B 1 339 ? 35.242  13.912  -0.123  1.00 94.46  ? 339 GLU B N   1 
ATOM   6101  C  CA  . GLU B 1 339 ? 35.807  15.151  -0.654  1.00 93.40  ? 339 GLU B CA  1 
ATOM   6102  C  C   . GLU B 1 339 ? 37.328  15.086  -0.763  1.00 91.73  ? 339 GLU B C   1 
ATOM   6103  O  O   . GLU B 1 339 ? 37.945  14.094  -0.359  1.00 93.24  ? 339 GLU B O   1 
ATOM   6104  C  CB  . GLU B 1 339 ? 35.393  16.336  0.226   1.00 90.52  ? 339 GLU B CB  1 
ATOM   6105  C  CG  . GLU B 1 339 ? 34.160  17.088  -0.259  1.00 92.74  ? 339 GLU B CG  1 
ATOM   6106  C  CD  . GLU B 1 339 ? 33.992  18.437  0.422   1.00 89.83  ? 339 GLU B CD  1 
ATOM   6107  O  OE1 . GLU B 1 339 ? 33.669  18.467  1.631   1.00 86.08  ? 339 GLU B OE1 1 
ATOM   6108  O  OE2 . GLU B 1 339 ? 34.204  19.469  -0.251  1.00 85.81  ? 339 GLU B OE2 1 
ATOM   6109  N  N   . LEU B 1 340 ? 37.944  16.137  -1.303  1.00 90.23  ? 340 LEU B N   1 
ATOM   6110  C  CA  . LEU B 1 340 ? 39.392  16.203  -1.422  1.00 91.91  ? 340 LEU B CA  1 
ATOM   6111  C  C   . LEU B 1 340 ? 39.934  17.397  -0.644  1.00 89.03  ? 340 LEU B C   1 
ATOM   6112  O  O   . LEU B 1 340 ? 39.392  18.508  -0.763  1.00 85.89  ? 340 LEU B O   1 
ATOM   6113  C  CB  . LEU B 1 340 ? 39.827  16.299  -2.902  1.00 86.62  ? 340 LEU B CB  1 
ATOM   6114  C  CG  . LEU B 1 340 ? 41.339  16.230  -3.162  1.00 87.27  ? 340 LEU B CG  1 
ATOM   6115  C  CD1 . LEU B 1 340 ? 41.892  14.867  -2.785  1.00 86.26  ? 340 LEU B CD1 1 
ATOM   6116  C  CD2 . LEU B 1 340 ? 41.691  16.563  -4.607  1.00 85.59  ? 340 LEU B CD2 1 
ATOM   6117  N  N   . PRO B 1 341 ? 40.990  17.209  0.178   1.00 91.75  ? 341 PRO B N   1 
ATOM   6118  C  CA  . PRO B 1 341 ? 41.619  18.344  0.877   1.00 94.83  ? 341 PRO B CA  1 
ATOM   6119  C  C   . PRO B 1 341 ? 42.159  19.433  -0.046  1.00 93.96  ? 341 PRO B C   1 
ATOM   6120  O  O   . PRO B 1 341 ? 43.210  19.262  -0.676  1.00 94.78  ? 341 PRO B O   1 
ATOM   6121  C  CB  . PRO B 1 341 ? 42.757  17.671  1.659   1.00 90.71  ? 341 PRO B CB  1 
ATOM   6122  C  CG  . PRO B 1 341 ? 42.243  16.294  1.933   1.00 88.06  ? 341 PRO B CG  1 
ATOM   6123  C  CD  . PRO B 1 341 ? 41.471  15.911  0.691   1.00 92.54  ? 341 PRO B CD  1 
ATOM   6124  N  N   . GLY B 1 342 ? 41.455  20.570  -0.111  1.00 93.69  ? 342 GLY B N   1 
ATOM   6125  C  CA  . GLY B 1 342 ? 41.822  21.701  -0.942  1.00 86.30  ? 342 GLY B CA  1 
ATOM   6126  C  C   . GLY B 1 342 ? 40.852  21.967  -2.080  1.00 86.18  ? 342 GLY B C   1 
ATOM   6127  O  O   . GLY B 1 342 ? 40.702  23.124  -2.496  1.00 87.94  ? 342 GLY B O   1 
ATOM   6128  N  N   . GLN B 1 343 ? 40.187  20.920  -2.583  1.00 87.36  ? 343 GLN B N   1 
ATOM   6129  C  CA  . GLN B 1 343 ? 39.282  21.067  -3.722  1.00 87.57  ? 343 GLN B CA  1 
ATOM   6130  C  C   . GLN B 1 343 ? 38.039  21.876  -3.362  1.00 90.16  ? 343 GLN B C   1 
ATOM   6131  O  O   . GLN B 1 343 ? 37.480  22.568  -4.223  1.00 91.11  ? 343 GLN B O   1 
ATOM   6132  C  CB  . GLN B 1 343 ? 38.889  19.683  -4.250  1.00 82.05  ? 343 GLN B CB  1 
ATOM   6133  C  CG  . GLN B 1 343 ? 37.904  19.695  -5.413  1.00 80.48  ? 343 GLN B CG  1 
ATOM   6134  C  CD  . GLN B 1 343 ? 36.452  19.651  -4.960  1.00 82.77  ? 343 GLN B CD  1 
ATOM   6135  O  OE1 . GLN B 1 343 ? 36.084  18.878  -4.071  1.00 84.47  ? 343 GLN B OE1 1 
ATOM   6136  N  NE2 . GLN B 1 343 ? 35.620  20.491  -5.567  1.00 78.65  ? 343 GLN B NE2 1 
ATOM   6137  N  N   . ARG B 1 344 ? 37.593  21.799  -2.105  1.00 87.16  ? 344 ARG B N   1 
ATOM   6138  C  CA  . ARG B 1 344 ? 36.432  22.518  -1.592  1.00 82.47  ? 344 ARG B CA  1 
ATOM   6139  C  C   . ARG B 1 344 ? 36.593  24.029  -1.758  1.00 82.89  ? 344 ARG B C   1 
ATOM   6140  O  O   . ARG B 1 344 ? 37.675  24.500  -2.139  1.00 80.43  ? 344 ARG B O   1 
ATOM   6141  C  CB  . ARG B 1 344 ? 36.227  22.153  -0.119  1.00 79.90  ? 344 ARG B CB  1 
ATOM   6142  C  CG  . ARG B 1 344 ? 37.106  22.955  0.832   1.00 78.22  ? 344 ARG B CG  1 
ATOM   6143  C  CD  . ARG B 1 344 ? 37.114  22.391  2.243   1.00 74.58  ? 344 ARG B CD  1 
ATOM   6144  N  NE  . ARG B 1 344 ? 35.790  21.957  2.673   1.00 74.25  ? 344 ARG B NE  1 
ATOM   6145  C  CZ  . ARG B 1 344 ? 35.372  21.973  3.930   1.00 69.79  ? 344 ARG B CZ  1 
ATOM   6146  N  NH1 . ARG B 1 344 ? 36.131  22.452  4.903   1.00 62.13  ? 344 ARG B NH1 1 
ATOM   6147  N  NH2 . ARG B 1 344 ? 34.165  21.491  4.220   1.00 68.00  ? 344 ARG B NH2 1 
ATOM   6148  N  N   . PRO B 1 345 ? 35.544  24.821  -1.516  1.00 84.62  ? 345 PRO B N   1 
ATOM   6149  C  CA  . PRO B 1 345 ? 35.725  26.280  -1.441  1.00 76.67  ? 345 PRO B CA  1 
ATOM   6150  C  C   . PRO B 1 345 ? 36.588  26.683  -0.249  1.00 74.66  ? 345 PRO B C   1 
ATOM   6151  O  O   . PRO B 1 345 ? 36.627  26.004  0.780   1.00 73.36  ? 345 PRO B O   1 
ATOM   6152  C  CB  . PRO B 1 345 ? 34.291  26.808  -1.294  1.00 73.74  ? 345 PRO B CB  1 
ATOM   6153  C  CG  . PRO B 1 345 ? 33.423  25.721  -1.883  1.00 72.58  ? 345 PRO B CG  1 
ATOM   6154  C  CD  . PRO B 1 345 ? 34.117  24.438  -1.528  1.00 75.93  ? 345 PRO B CD  1 
ATOM   6155  N  N   . ALA B 1 346 ? 37.278  27.819  -0.391  1.00 69.85  ? 346 ALA B N   1 
ATOM   6156  C  CA  . ALA B 1 346 ? 38.288  28.200  0.597   1.00 66.72  ? 346 ALA B CA  1 
ATOM   6157  C  C   . ALA B 1 346 ? 37.659  28.584  1.934   1.00 68.75  ? 346 ALA B C   1 
ATOM   6158  O  O   . ALA B 1 346 ? 38.088  28.109  2.996   1.00 59.91  ? 346 ALA B O   1 
ATOM   6159  C  CB  . ALA B 1 346 ? 39.138  29.352  0.059   1.00 65.27  ? 346 ALA B CB  1 
ATOM   6160  N  N   . PHE B 1 347 ? 36.639  29.448  1.899   1.00 67.30  ? 347 PHE B N   1 
ATOM   6161  C  CA  . PHE B 1 347 ? 36.071  30.036  3.109   1.00 59.06  ? 347 PHE B CA  1 
ATOM   6162  C  C   . PHE B 1 347 ? 35.355  29.021  3.995   1.00 56.98  ? 347 PHE B C   1 
ATOM   6163  O  O   . PHE B 1 347 ? 35.127  29.305  5.177   1.00 53.87  ? 347 PHE B O   1 
ATOM   6164  C  CB  . PHE B 1 347 ? 35.089  31.145  2.736   1.00 55.70  ? 347 PHE B CB  1 
ATOM   6165  C  CG  . PHE B 1 347 ? 33.877  30.649  2.015   1.00 53.84  ? 347 PHE B CG  1 
ATOM   6166  C  CD1 . PHE B 1 347 ? 33.935  30.356  0.666   1.00 56.57  ? 347 PHE B CD1 1 
ATOM   6167  C  CD2 . PHE B 1 347 ? 32.682  30.458  2.694   1.00 50.48  ? 347 PHE B CD2 1 
ATOM   6168  C  CE1 . PHE B 1 347 ? 32.827  29.889  0.005   1.00 63.78  ? 347 PHE B CE1 1 
ATOM   6169  C  CE2 . PHE B 1 347 ? 31.565  29.993  2.038   1.00 56.26  ? 347 PHE B CE2 1 
ATOM   6170  C  CZ  . PHE B 1 347 ? 31.634  29.705  0.694   1.00 62.54  ? 347 PHE B CZ  1 
ATOM   6171  N  N   . LEU B 1 348 ? 34.978  27.859  3.454   1.00 63.43  ? 348 LEU B N   1 
ATOM   6172  C  CA  . LEU B 1 348 ? 34.324  26.836  4.262   1.00 57.76  ? 348 LEU B CA  1 
ATOM   6173  C  C   . LEU B 1 348 ? 35.182  26.390  5.438   1.00 52.24  ? 348 LEU B C   1 
ATOM   6174  O  O   . LEU B 1 348 ? 34.687  25.671  6.313   1.00 50.26  ? 348 LEU B O   1 
ATOM   6175  C  CB  . LEU B 1 348 ? 33.950  25.637  3.383   1.00 61.82  ? 348 LEU B CB  1 
ATOM   6176  C  CG  . LEU B 1 348 ? 32.847  25.910  2.361   1.00 63.26  ? 348 LEU B CG  1 
ATOM   6177  C  CD1 . LEU B 1 348 ? 32.407  24.622  1.692   1.00 68.04  ? 348 LEU B CD1 1 
ATOM   6178  C  CD2 . LEU B 1 348 ? 31.658  26.605  3.017   1.00 60.64  ? 348 LEU B CD2 1 
ATOM   6179  N  N   . ASP B 1 349 ? 36.448  26.792  5.474   1.00 52.96  ? 349 ASP B N   1 
ATOM   6180  C  CA  . ASP B 1 349 ? 37.302  26.581  6.630   1.00 54.95  ? 349 ASP B CA  1 
ATOM   6181  C  C   . ASP B 1 349 ? 37.164  27.698  7.657   1.00 48.69  ? 349 ASP B C   1 
ATOM   6182  O  O   . ASP B 1 349 ? 37.776  27.617  8.727   1.00 48.45  ? 349 ASP B O   1 
ATOM   6183  C  CB  . ASP B 1 349 ? 38.757  26.461  6.178   1.00 58.20  ? 349 ASP B CB  1 
ATOM   6184  C  CG  . ASP B 1 349 ? 39.044  25.138  5.502   1.00 59.27  ? 349 ASP B CG  1 
ATOM   6185  O  OD1 . ASP B 1 349 ? 38.743  24.074  6.083   1.00 62.43  ? 349 ASP B OD1 1 
ATOM   6186  O  OD2 . ASP B 1 349 ? 39.548  25.170  4.360   1.00 67.66  ? 349 ASP B OD2 1 
ATOM   6187  N  N   . GLY B 1 350 ? 36.382  28.733  7.347   1.00 48.91  ? 350 GLY B N   1 
ATOM   6188  C  CA  . GLY B 1 350 ? 36.130  29.834  8.252   1.00 40.79  ? 350 GLY B CA  1 
ATOM   6189  C  C   . GLY B 1 350 ? 36.975  31.047  7.933   1.00 43.97  ? 350 GLY B C   1 
ATOM   6190  O  O   . GLY B 1 350 ? 38.171  30.910  7.663   1.00 46.40  ? 350 GLY B O   1 
ATOM   6191  N  N   . ILE B 1 351 ? 36.384  32.243  7.970   1.00 42.20  ? 351 ILE B N   1 
ATOM   6192  C  CA  . ILE B 1 351 ? 37.141  33.459  7.683   1.00 44.81  ? 351 ILE B CA  1 
ATOM   6193  C  C   . ILE B 1 351 ? 37.501  34.261  8.927   1.00 44.12  ? 351 ILE B C   1 
ATOM   6194  O  O   . ILE B 1 351 ? 38.210  35.270  8.805   1.00 41.02  ? 351 ILE B O   1 
ATOM   6195  C  CB  . ILE B 1 351 ? 36.398  34.361  6.678   1.00 41.35  ? 351 ILE B CB  1 
ATOM   6196  C  CG1 . ILE B 1 351 ? 35.201  35.038  7.353   1.00 42.63  ? 351 ILE B CG1 1 
ATOM   6197  C  CG2 . ILE B 1 351 ? 36.021  33.543  5.431   1.00 40.14  ? 351 ILE B CG2 1 
ATOM   6198  C  CD1 . ILE B 1 351 ? 34.367  35.913  6.431   1.00 40.26  ? 351 ILE B CD1 1 
ATOM   6199  N  N   . HIS B 1 352 ? 37.023  33.868  10.111  1.00 45.85  ? 352 HIS B N   1 
ATOM   6200  C  CA  . HIS B 1 352 ? 37.597  34.335  11.379  1.00 41.80  ? 352 HIS B CA  1 
ATOM   6201  C  C   . HIS B 1 352 ? 37.478  35.850  11.554  1.00 48.75  ? 352 HIS B C   1 
ATOM   6202  O  O   . HIS B 1 352 ? 38.392  36.500  12.062  1.00 50.05  ? 352 HIS B O   1 
ATOM   6203  C  CB  . HIS B 1 352 ? 39.063  33.893  11.496  1.00 44.45  ? 352 HIS B CB  1 
ATOM   6204  C  CG  . HIS B 1 352 ? 39.570  33.779  12.906  1.00 53.27  ? 352 HIS B CG  1 
ATOM   6205  N  ND1 . HIS B 1 352 ? 40.420  32.769  13.311  1.00 54.15  ? 352 HIS B ND1 1 
ATOM   6206  C  CD2 . HIS B 1 352 ? 39.367  34.557  13.999  1.00 56.09  ? 352 HIS B CD2 1 
ATOM   6207  C  CE1 . HIS B 1 352 ? 40.707  32.923  14.593  1.00 58.97  ? 352 HIS B CE1 1 
ATOM   6208  N  NE2 . HIS B 1 352 ? 40.080  34.000  15.035  1.00 56.93  ? 352 HIS B NE2 1 
ATOM   6209  N  N   . VAL B 1 353 ? 36.348  36.432  11.144  1.00 45.08  ? 353 VAL B N   1 
ATOM   6210  C  CA  . VAL B 1 353 ? 36.155  37.859  11.378  1.00 42.84  ? 353 VAL B CA  1 
ATOM   6211  C  C   . VAL B 1 353 ? 36.252  38.147  12.872  1.00 49.63  ? 353 VAL B C   1 
ATOM   6212  O  O   . VAL B 1 353 ? 35.706  37.414  13.707  1.00 45.95  ? 353 VAL B O   1 
ATOM   6213  C  CB  . VAL B 1 353 ? 34.814  38.352  10.807  1.00 42.68  ? 353 VAL B CB  1 
ATOM   6214  C  CG1 . VAL B 1 353 ? 34.531  39.783  11.278  1.00 40.65  ? 353 VAL B CG1 1 
ATOM   6215  C  CG2 . VAL B 1 353 ? 34.816  38.290  9.284   1.00 37.25  ? 353 VAL B CG2 1 
ATOM   6216  N  N   . ASP B 1 354 ? 36.973  39.209  13.218  1.00 47.42  ? 354 ASP B N   1 
ATOM   6217  C  CA  . ASP B 1 354 ? 37.130  39.567  14.620  1.00 48.09  ? 354 ASP B CA  1 
ATOM   6218  C  C   . ASP B 1 354 ? 35.777  39.982  15.182  1.00 46.46  ? 354 ASP B C   1 
ATOM   6219  O  O   . ASP B 1 354 ? 35.111  40.844  14.598  1.00 45.21  ? 354 ASP B O   1 
ATOM   6220  C  CB  . ASP B 1 354 ? 38.137  40.707  14.777  1.00 48.43  ? 354 ASP B CB  1 
ATOM   6221  C  CG  . ASP B 1 354 ? 38.716  40.795  16.179  1.00 51.87  ? 354 ASP B CG  1 
ATOM   6222  O  OD1 . ASP B 1 354 ? 38.352  39.975  17.056  1.00 49.77  ? 354 ASP B OD1 1 
ATOM   6223  O  OD2 . ASP B 1 354 ? 39.555  41.697  16.398  1.00 54.43  ? 354 ASP B OD2 1 
ATOM   6224  N  N   . PRO B 1 355 ? 35.329  39.388  16.290  1.00 42.30  ? 355 PRO B N   1 
ATOM   6225  C  CA  . PRO B 1 355 ? 34.027  39.783  16.849  1.00 39.02  ? 355 PRO B CA  1 
ATOM   6226  C  C   . PRO B 1 355 ? 33.946  41.253  17.196  1.00 43.04  ? 355 PRO B C   1 
ATOM   6227  O  O   . PRO B 1 355 ? 32.852  41.830  17.155  1.00 40.18  ? 355 PRO B O   1 
ATOM   6228  C  CB  . PRO B 1 355 ? 33.907  38.897  18.093  1.00 39.84  ? 355 PRO B CB  1 
ATOM   6229  C  CG  . PRO B 1 355 ? 34.692  37.685  17.731  1.00 38.79  ? 355 PRO B CG  1 
ATOM   6230  C  CD  . PRO B 1 355 ? 35.839  38.147  16.895  1.00 36.53  ? 355 PRO B CD  1 
ATOM   6231  N  N   . ASN B 1 356 ? 35.076  41.884  17.528  1.00 43.46  ? 356 ASN B N   1 
ATOM   6232  C  CA  . ASN B 1 356 ? 35.061  43.300  17.863  1.00 44.31  ? 356 ASN B CA  1 
ATOM   6233  C  C   . ASN B 1 356 ? 34.696  44.175  16.676  1.00 40.89  ? 356 ASN B C   1 
ATOM   6234  O  O   . ASN B 1 356 ? 34.223  45.296  16.879  1.00 41.18  ? 356 ASN B O   1 
ATOM   6235  C  CB  . ASN B 1 356 ? 36.416  43.720  18.438  1.00 47.55  ? 356 ASN B CB  1 
ATOM   6236  C  CG  . ASN B 1 356 ? 36.593  43.283  19.882  1.00 46.29  ? 356 ASN B CG  1 
ATOM   6237  O  OD1 . ASN B 1 356 ? 35.883  43.752  20.772  1.00 47.65  ? 356 ASN B OD1 1 
ATOM   6238  N  ND2 . ASN B 1 356 ? 37.533  42.374  20.121  1.00 45.50  ? 356 ASN B ND2 1 
ATOM   6239  N  N   . ASP B 1 357 ? 34.863  43.688  15.446  1.00 43.67  ? 357 ASP B N   1 
ATOM   6240  C  CA  . ASP B 1 357 ? 34.525  44.520  14.297  1.00 42.64  ? 357 ASP B CA  1 
ATOM   6241  C  C   . ASP B 1 357 ? 33.052  44.882  14.252  1.00 43.65  ? 357 ASP B C   1 
ATOM   6242  O  O   . ASP B 1 357 ? 32.655  45.665  13.383  1.00 37.72  ? 357 ASP B O   1 
ATOM   6243  C  CB  . ASP B 1 357 ? 34.900  43.820  12.984  1.00 52.10  ? 357 ASP B CB  1 
ATOM   6244  C  CG  . ASP B 1 357 ? 36.390  43.596  12.845  1.00 48.28  ? 357 ASP B CG  1 
ATOM   6245  O  OD1 . ASP B 1 357 ? 37.154  44.178  13.634  1.00 50.29  ? 357 ASP B OD1 1 
ATOM   6246  O  OD2 . ASP B 1 357 ? 36.795  42.818  11.956  1.00 53.53  ? 357 ASP B OD2 1 
ATOM   6247  N  N   . VAL B 1 358 ? 32.224  44.317  15.138  1.00 40.91  ? 358 VAL B N   1 
ATOM   6248  C  CA  . VAL B 1 358 ? 30.820  44.705  15.122  1.00 39.61  ? 358 VAL B CA  1 
ATOM   6249  C  C   . VAL B 1 358 ? 30.618  46.086  15.731  1.00 42.24  ? 358 VAL B C   1 
ATOM   6250  O  O   . VAL B 1 358 ? 29.638  46.761  15.392  1.00 42.95  ? 358 VAL B O   1 
ATOM   6251  C  CB  . VAL B 1 358 ? 29.940  43.641  15.813  1.00 37.60  ? 358 VAL B CB  1 
ATOM   6252  C  CG1 . VAL B 1 358 ? 30.269  42.274  15.258  1.00 37.97  ? 358 VAL B CG1 1 
ATOM   6253  C  CG2 . VAL B 1 358 ? 30.126  43.647  17.324  1.00 36.65  ? 358 VAL B CG2 1 
ATOM   6254  N  N   . PHE B 1 359 ? 31.541  46.543  16.591  1.00 41.39  ? 359 PHE B N   1 
ATOM   6255  C  CA  . PHE B 1 359 ? 31.405  47.864  17.206  1.00 40.97  ? 359 PHE B CA  1 
ATOM   6256  C  C   . PHE B 1 359 ? 31.297  48.963  16.158  1.00 41.20  ? 359 PHE B C   1 
ATOM   6257  O  O   . PHE B 1 359 ? 30.562  49.939  16.352  1.00 44.96  ? 359 PHE B O   1 
ATOM   6258  C  CB  . PHE B 1 359 ? 32.590  48.139  18.137  1.00 39.94  ? 359 PHE B CB  1 
ATOM   6259  C  CG  . PHE B 1 359 ? 32.568  47.334  19.413  1.00 42.98  ? 359 PHE B CG  1 
ATOM   6260  C  CD1 . PHE B 1 359 ? 31.780  47.719  20.484  1.00 43.74  ? 359 PHE B CD1 1 
ATOM   6261  C  CD2 . PHE B 1 359 ? 33.339  46.192  19.547  1.00 42.62  ? 359 PHE B CD2 1 
ATOM   6262  C  CE1 . PHE B 1 359 ? 31.769  46.971  21.663  1.00 37.12  ? 359 PHE B CE1 1 
ATOM   6263  C  CE2 . PHE B 1 359 ? 33.325  45.449  20.730  1.00 42.75  ? 359 PHE B CE2 1 
ATOM   6264  C  CZ  . PHE B 1 359 ? 32.541  45.845  21.782  1.00 33.57  ? 359 PHE B CZ  1 
ATOM   6265  N  N   . ASP B 1 360 ? 31.998  48.814  15.034  1.00 42.86  ? 360 ASP B N   1 
ATOM   6266  C  CA  . ASP B 1 360 ? 31.976  49.848  14.005  1.00 44.42  ? 360 ASP B CA  1 
ATOM   6267  C  C   . ASP B 1 360 ? 30.732  49.791  13.137  1.00 48.79  ? 360 ASP B C   1 
ATOM   6268  O  O   . ASP B 1 360 ? 30.404  50.785  12.478  1.00 44.96  ? 360 ASP B O   1 
ATOM   6269  C  CB  . ASP B 1 360 ? 33.208  49.738  13.109  1.00 41.76  ? 360 ASP B CB  1 
ATOM   6270  C  CG  . ASP B 1 360 ? 34.494  49.825  13.888  1.00 39.06  ? 360 ASP B CG  1 
ATOM   6271  O  OD1 . ASP B 1 360 ? 34.493  50.410  15.000  1.00 40.10  ? 360 ASP B OD1 1 
ATOM   6272  O  OD2 . ASP B 1 360 ? 35.500  49.291  13.392  1.00 41.40  ? 360 ASP B OD2 1 
ATOM   6273  N  N   . VAL B 1 361 ? 30.029  48.663  13.111  1.00 50.04  ? 361 VAL B N   1 
ATOM   6274  C  CA  . VAL B 1 361 ? 28.843  48.547  12.272  1.00 49.00  ? 361 VAL B CA  1 
ATOM   6275  C  C   . VAL B 1 361 ? 27.557  48.455  13.085  1.00 40.46  ? 361 VAL B C   1 
ATOM   6276  O  O   . VAL B 1 361 ? 26.470  48.641  12.514  1.00 40.33  ? 361 VAL B O   1 
ATOM   6277  C  CB  . VAL B 1 361 ? 28.966  47.361  11.287  1.00 43.60  ? 361 VAL B CB  1 
ATOM   6278  C  CG1 . VAL B 1 361 ? 30.022  47.674  10.227  1.00 42.91  ? 361 VAL B CG1 1 
ATOM   6279  C  CG2 . VAL B 1 361 ? 29.316  46.081  12.005  1.00 42.22  ? 361 VAL B CG2 1 
ATOM   6280  N  N   . ILE B 1 362 ? 27.649  48.291  14.407  1.00 41.66  ? 362 ILE B N   1 
ATOM   6281  C  CA  . ILE B 1 362 ? 26.517  47.818  15.201  1.00 40.84  ? 362 ILE B CA  1 
ATOM   6282  C  C   . ILE B 1 362 ? 25.321  48.754  15.135  1.00 45.28  ? 362 ILE B C   1 
ATOM   6283  O  O   . ILE B 1 362 ? 24.171  48.305  15.241  1.00 40.55  ? 362 ILE B O   1 
ATOM   6284  C  CB  . ILE B 1 362 ? 26.951  47.581  16.659  1.00 43.77  ? 362 ILE B CB  1 
ATOM   6285  C  CG1 . ILE B 1 362 ? 26.029  46.547  17.306  1.00 44.58  ? 362 ILE B CG1 1 
ATOM   6286  C  CG2 . ILE B 1 362 ? 26.945  48.884  17.455  1.00 48.06  ? 362 ILE B CG2 1 
ATOM   6287  C  CD1 . ILE B 1 362 ? 26.038  45.211  16.604  1.00 38.07  ? 362 ILE B CD1 1 
ATOM   6288  N  N   . GLU B 1 363 ? 25.548  50.057  14.958  1.00 46.65  ? 363 GLU B N   1 
ATOM   6289  C  CA  . GLU B 1 363 ? 24.419  50.976  14.980  1.00 44.35  ? 363 GLU B CA  1 
ATOM   6290  C  C   . GLU B 1 363 ? 23.480  50.743  13.799  1.00 42.51  ? 363 GLU B C   1 
ATOM   6291  O  O   . GLU B 1 363 ? 22.311  51.138  13.856  1.00 43.34  ? 363 GLU B O   1 
ATOM   6292  C  CB  . GLU B 1 363 ? 24.924  52.419  15.002  1.00 52.78  ? 363 GLU B CB  1 
ATOM   6293  C  CG  . GLU B 1 363 ? 23.833  53.471  15.168  1.00 60.94  ? 363 GLU B CG  1 
ATOM   6294  C  CD  . GLU B 1 363 ? 24.385  54.884  15.216  1.00 71.60  ? 363 GLU B CD  1 
ATOM   6295  O  OE1 . GLU B 1 363 ? 25.611  55.050  15.017  1.00 65.48  ? 363 GLU B OE1 1 
ATOM   6296  O  OE2 . GLU B 1 363 ? 23.596  55.825  15.464  1.00 76.37  ? 363 GLU B OE2 1 
ATOM   6297  N  N   . ASN B 1 364 ? 23.955  50.097  12.739  1.00 43.14  ? 364 ASN B N   1 
ATOM   6298  C  CA  . ASN B 1 364 ? 23.133  49.782  11.581  1.00 42.46  ? 364 ASN B CA  1 
ATOM   6299  C  C   . ASN B 1 364 ? 22.849  48.292  11.452  1.00 36.22  ? 364 ASN B C   1 
ATOM   6300  O  O   . ASN B 1 364 ? 22.362  47.854  10.400  1.00 36.06  ? 364 ASN B O   1 
ATOM   6301  C  CB  . ASN B 1 364 ? 23.808  50.279  10.306  1.00 38.68  ? 364 ASN B CB  1 
ATOM   6302  C  CG  . ASN B 1 364 ? 24.064  51.765  10.327  1.00 46.68  ? 364 ASN B CG  1 
ATOM   6303  O  OD1 . ASN B 1 364 ? 23.132  52.568  10.291  1.00 50.41  ? 364 ASN B OD1 1 
ATOM   6304  N  ND2 . ASN B 1 364 ? 25.335  52.142  10.388  1.00 43.88  ? 364 ASN B ND2 1 
ATOM   6305  N  N   . VAL B 1 365 ? 23.181  47.498  12.465  1.00 38.67  ? 365 VAL B N   1 
ATOM   6306  C  CA  . VAL B 1 365 ? 22.870  46.070  12.474  1.00 34.95  ? 365 VAL B CA  1 
ATOM   6307  C  C   . VAL B 1 365 ? 21.467  45.899  13.042  1.00 38.33  ? 365 VAL B C   1 
ATOM   6308  O  O   . VAL B 1 365 ? 21.201  46.243  14.202  1.00 33.86  ? 365 VAL B O   1 
ATOM   6309  C  CB  . VAL B 1 365 ? 23.905  45.276  13.282  1.00 35.08  ? 365 VAL B CB  1 
ATOM   6310  C  CG1 . VAL B 1 365 ? 23.455  43.823  13.453  1.00 34.28  ? 365 VAL B CG1 1 
ATOM   6311  C  CG2 . VAL B 1 365 ? 25.240  45.318  12.572  1.00 36.18  ? 365 VAL B CG2 1 
ATOM   6312  N  N   . VAL B 1 366 ? 20.555  45.405  12.217  1.00 34.53  ? 366 VAL B N   1 
ATOM   6313  C  CA  . VAL B 1 366 ? 19.163  45.295  12.623  1.00 28.41  ? 366 VAL B CA  1 
ATOM   6314  C  C   . VAL B 1 366 ? 18.747  43.860  12.939  1.00 31.78  ? 366 VAL B C   1 
ATOM   6315  O  O   . VAL B 1 366 ? 17.711  43.672  13.592  1.00 30.59  ? 366 VAL B O   1 
ATOM   6316  C  CB  . VAL B 1 366 ? 18.231  45.903  11.559  1.00 32.36  ? 366 VAL B CB  1 
ATOM   6317  C  CG1 . VAL B 1 366 ? 18.430  47.430  11.493  1.00 27.05  ? 366 VAL B CG1 1 
ATOM   6318  C  CG2 . VAL B 1 366 ? 18.502  45.276  10.204  1.00 30.03  ? 366 VAL B CG2 1 
ATOM   6319  N  N   . PHE B 1 367 ? 19.512  42.851  12.514  1.00 31.98  ? 367 PHE B N   1 
ATOM   6320  C  CA  . PHE B 1 367 ? 19.071  41.467  12.621  1.00 36.15  ? 367 PHE B CA  1 
ATOM   6321  C  C   . PHE B 1 367 ? 20.287  40.565  12.491  1.00 33.08  ? 367 PHE B C   1 
ATOM   6322  O  O   . PHE B 1 367 ? 21.223  40.875  11.750  1.00 30.06  ? 367 PHE B O   1 
ATOM   6323  C  CB  . PHE B 1 367 ? 18.027  41.135  11.541  1.00 28.50  ? 367 PHE B CB  1 
ATOM   6324  C  CG  . PHE B 1 367 ? 17.265  39.858  11.796  1.00 32.35  ? 367 PHE B CG  1 
ATOM   6325  C  CD1 . PHE B 1 367 ? 16.240  39.817  12.725  1.00 32.66  ? 367 PHE B CD1 1 
ATOM   6326  C  CD2 . PHE B 1 367 ? 17.573  38.704  11.098  1.00 34.21  ? 367 PHE B CD2 1 
ATOM   6327  C  CE1 . PHE B 1 367 ? 15.541  38.648  12.972  1.00 32.00  ? 367 PHE B CE1 1 
ATOM   6328  C  CE2 . PHE B 1 367 ? 16.859  37.519  11.330  1.00 33.81  ? 367 PHE B CE2 1 
ATOM   6329  C  CZ  . PHE B 1 367 ? 15.846  37.503  12.270  1.00 28.97  ? 367 PHE B CZ  1 
ATOM   6330  N  N   . ILE B 1 368 ? 20.268  39.445  13.214  1.00 28.26  ? 368 ILE B N   1 
ATOM   6331  C  CA  . ILE B 1 368 ? 21.395  38.524  13.202  1.00 27.83  ? 368 ILE B CA  1 
ATOM   6332  C  C   . ILE B 1 368 ? 20.890  37.109  12.979  1.00 29.85  ? 368 ILE B C   1 
ATOM   6333  O  O   . ILE B 1 368 ? 20.094  36.592  13.774  1.00 30.94  ? 368 ILE B O   1 
ATOM   6334  C  CB  . ILE B 1 368 ? 22.228  38.603  14.488  1.00 27.96  ? 368 ILE B CB  1 
ATOM   6335  C  CG1 . ILE B 1 368 ? 22.652  40.049  14.738  1.00 30.36  ? 368 ILE B CG1 1 
ATOM   6336  C  CG2 . ILE B 1 368 ? 23.445  37.694  14.375  1.00 28.25  ? 368 ILE B CG2 1 
ATOM   6337  C  CD1 . ILE B 1 368 ? 23.710  40.188  15.810  1.00 35.78  ? 368 ILE B CD1 1 
ATOM   6338  N  N   . GLN B 1 369 ? 21.356  36.489  11.902  1.00 24.62  ? 369 GLN B N   1 
ATOM   6339  C  CA  . GLN B 1 369 ? 21.174  35.066  11.676  1.00 29.11  ? 369 GLN B CA  1 
ATOM   6340  C  C   . GLN B 1 369 ? 22.278  34.300  12.385  1.00 30.36  ? 369 GLN B C   1 
ATOM   6341  O  O   . GLN B 1 369 ? 23.462  34.478  12.077  1.00 32.12  ? 369 GLN B O   1 
ATOM   6342  C  CB  . GLN B 1 369 ? 21.197  34.769  10.189  1.00 24.67  ? 369 GLN B CB  1 
ATOM   6343  C  CG  . GLN B 1 369 ? 20.040  35.385  9.467   1.00 24.20  ? 369 GLN B CG  1 
ATOM   6344  C  CD  . GLN B 1 369 ? 20.195  35.245  7.974   1.00 31.16  ? 369 GLN B CD  1 
ATOM   6345  O  OE1 . GLN B 1 369 ? 21.301  34.956  7.473   1.00 25.30  ? 369 GLN B OE1 1 
ATOM   6346  N  NE2 . GLN B 1 369 ? 19.082  35.406  7.245   1.00 27.66  ? 369 GLN B NE2 1 
ATOM   6347  N  N   . ALA B 1 370 ? 21.889  33.448  13.330  1.00 24.70  ? 370 ALA B N   1 
ATOM   6348  C  CA  . ALA B 1 370 ? 22.833  32.657  14.105  1.00 28.03  ? 370 ALA B CA  1 
ATOM   6349  C  C   . ALA B 1 370 ? 23.095  31.376  13.334  1.00 27.47  ? 370 ALA B C   1 
ATOM   6350  O  O   . ALA B 1 370 ? 22.553  30.296  13.613  1.00 29.77  ? 370 ALA B O   1 
ATOM   6351  C  CB  . ALA B 1 370 ? 22.303  32.392  15.506  1.00 31.03  ? 370 ALA B CB  1 
ATOM   6352  N  N   . LYS B 1 371 ? 23.954  31.514  12.344  1.00 28.91  ? 371 LYS B N   1 
ATOM   6353  C  CA  . LYS B 1 371 ? 24.395  30.373  11.564  1.00 29.49  ? 371 LYS B CA  1 
ATOM   6354  C  C   . LYS B 1 371 ? 25.312  29.511  12.422  1.00 32.74  ? 371 LYS B C   1 
ATOM   6355  O  O   . LYS B 1 371 ? 26.175  30.019  13.145  1.00 28.70  ? 371 LYS B O   1 
ATOM   6356  C  CB  . LYS B 1 371 ? 25.102  30.844  10.293  1.00 25.47  ? 371 LYS B CB  1 
ATOM   6357  C  CG  . LYS B 1 371 ? 25.900  29.750  9.612   1.00 34.44  ? 371 LYS B CG  1 
ATOM   6358  C  CD  . LYS B 1 371 ? 25.158  29.102  8.441   1.00 32.87  ? 371 LYS B CD  1 
ATOM   6359  C  CE  . LYS B 1 371 ? 24.109  30.003  7.821   1.00 31.70  ? 371 LYS B CE  1 
ATOM   6360  N  NZ  . LYS B 1 371 ? 24.750  31.040  6.950   1.00 38.75  ? 371 LYS B NZ  1 
ATOM   6361  N  N   . PHE B 1 372 ? 25.068  28.207  12.398  1.00 25.38  ? 372 PHE B N   1 
ATOM   6362  C  CA  . PHE B 1 372 ? 25.912  27.239  13.069  1.00 28.20  ? 372 PHE B CA  1 
ATOM   6363  C  C   . PHE B 1 372 ? 25.852  25.963  12.238  1.00 26.24  ? 372 PHE B C   1 
ATOM   6364  O  O   . PHE B 1 372 ? 25.066  25.866  11.302  1.00 26.25  ? 372 PHE B O   1 
ATOM   6365  C  CB  . PHE B 1 372 ? 25.481  27.049  14.530  1.00 30.02  ? 372 PHE B CB  1 
ATOM   6366  C  CG  . PHE B 1 372 ? 24.200  26.273  14.701  1.00 29.61  ? 372 PHE B CG  1 
ATOM   6367  C  CD1 . PHE B 1 372 ? 22.995  26.797  14.280  1.00 28.30  ? 372 PHE B CD1 1 
ATOM   6368  C  CD2 . PHE B 1 372 ? 24.211  25.022  15.288  1.00 29.61  ? 372 PHE B CD2 1 
ATOM   6369  C  CE1 . PHE B 1 372 ? 21.827  26.084  14.436  1.00 29.58  ? 372 PHE B CE1 1 
ATOM   6370  C  CE2 . PHE B 1 372 ? 23.045  24.304  15.442  1.00 31.32  ? 372 PHE B CE2 1 
ATOM   6371  C  CZ  . PHE B 1 372 ? 21.851  24.840  15.005  1.00 28.29  ? 372 PHE B CZ  1 
ATOM   6372  N  N   . HIS B 1 373 ? 26.721  24.997  12.546  1.00 27.83  ? 373 HIS B N   1 
ATOM   6373  C  CA  . HIS B 1 373 ? 26.736  23.767  11.757  1.00 31.53  ? 373 HIS B CA  1 
ATOM   6374  C  C   . HIS B 1 373 ? 26.586  22.521  12.613  1.00 30.81  ? 373 HIS B C   1 
ATOM   6375  O  O   . HIS B 1 373 ? 26.037  21.517  12.156  1.00 34.80  ? 373 HIS B O   1 
ATOM   6376  C  CB  . HIS B 1 373 ? 28.019  23.655  10.932  1.00 29.29  ? 373 HIS B CB  1 
ATOM   6377  C  CG  . HIS B 1 373 ? 28.235  24.816  10.010  1.00 34.01  ? 373 HIS B CG  1 
ATOM   6378  N  ND1 . HIS B 1 373 ? 28.938  25.939  10.387  1.00 34.85  ? 373 HIS B ND1 1 
ATOM   6379  C  CD2 . HIS B 1 373 ? 27.810  25.046  8.745   1.00 35.33  ? 373 HIS B CD2 1 
ATOM   6380  C  CE1 . HIS B 1 373 ? 28.943  26.809  9.394   1.00 31.34  ? 373 HIS B CE1 1 
ATOM   6381  N  NE2 . HIS B 1 373 ? 28.268  26.292  8.385   1.00 38.74  ? 373 HIS B NE2 1 
ATOM   6382  N  N   . ASP B 1 374 ? 27.078  22.562  13.842  1.00 31.96  ? 374 ASP B N   1 
ATOM   6383  C  CA  . ASP B 1 374 ? 27.251  21.328  14.594  1.00 30.53  ? 374 ASP B CA  1 
ATOM   6384  C  C   . ASP B 1 374 ? 27.552  21.627  16.058  1.00 33.46  ? 374 ASP B C   1 
ATOM   6385  O  O   . ASP B 1 374 ? 28.555  22.269  16.377  1.00 35.82  ? 374 ASP B O   1 
ATOM   6386  C  CB  . ASP B 1 374 ? 28.375  20.499  13.959  1.00 31.28  ? 374 ASP B CB  1 
ATOM   6387  C  CG  . ASP B 1 374 ? 28.558  19.161  14.612  1.00 33.28  ? 374 ASP B CG  1 
ATOM   6388  O  OD1 . ASP B 1 374 ? 27.620  18.701  15.291  1.00 35.18  ? 374 ASP B OD1 1 
ATOM   6389  O  OD2 . ASP B 1 374 ? 29.630  18.552  14.416  1.00 37.51  ? 374 ASP B OD2 1 
ATOM   6390  N  N   . ILE B 1 375 ? 26.683  21.170  16.953  1.00 33.74  ? 375 ILE B N   1 
ATOM   6391  C  CA  . ILE B 1 375 ? 26.841  21.334  18.390  1.00 31.98  ? 375 ILE B CA  1 
ATOM   6392  C  C   . ILE B 1 375 ? 26.571  19.973  19.011  1.00 31.11  ? 375 ILE B C   1 
ATOM   6393  O  O   . ILE B 1 375 ? 25.517  19.376  18.762  1.00 31.48  ? 375 ILE B O   1 
ATOM   6394  C  CB  . ILE B 1 375 ? 25.898  22.413  18.955  1.00 32.30  ? 375 ILE B CB  1 
ATOM   6395  C  CG1 . ILE B 1 375 ? 26.129  23.757  18.238  1.00 34.71  ? 375 ILE B CG1 1 
ATOM   6396  C  CG2 . ILE B 1 375 ? 26.055  22.547  20.483  1.00 31.04  ? 375 ILE B CG2 1 
ATOM   6397  C  CD1 . ILE B 1 375 ? 25.188  24.897  18.675  1.00 27.12  ? 375 ILE B CD1 1 
ATOM   6398  N  N   . ASP B 1 376 ? 27.533  19.461  19.776  1.00 29.42  ? 376 ASP B N   1 
ATOM   6399  C  CA  . ASP B 1 376 ? 27.452  18.100  20.290  1.00 33.43  ? 376 ASP B CA  1 
ATOM   6400  C  C   . ASP B 1 376 ? 26.761  18.069  21.660  1.00 31.35  ? 376 ASP B C   1 
ATOM   6401  O  O   . ASP B 1 376 ? 26.224  19.065  22.142  1.00 32.94  ? 376 ASP B O   1 
ATOM   6402  C  CB  . ASP B 1 376 ? 28.844  17.459  20.340  1.00 38.83  ? 376 ASP B CB  1 
ATOM   6403  C  CG  . ASP B 1 376 ? 29.761  18.077  21.404  1.00 35.13  ? 376 ASP B CG  1 
ATOM   6404  O  OD1 . ASP B 1 376 ? 29.271  18.701  22.362  1.00 35.00  ? 376 ASP B OD1 1 
ATOM   6405  O  OD2 . ASP B 1 376 ? 30.994  17.912  21.290  1.00 40.19  ? 376 ASP B OD2 1 
ATOM   6406  N  N   . GLU B 1 377 ? 26.810  16.914  22.324  1.00 35.03  ? 377 GLU B N   1 
ATOM   6407  C  CA  . GLU B 1 377 ? 25.986  16.656  23.495  1.00 37.28  ? 377 GLU B CA  1 
ATOM   6408  C  C   . GLU B 1 377 ? 26.456  17.399  24.739  1.00 42.33  ? 377 GLU B C   1 
ATOM   6409  O  O   . GLU B 1 377 ? 25.694  17.487  25.714  1.00 36.10  ? 377 GLU B O   1 
ATOM   6410  C  CB  . GLU B 1 377 ? 25.942  15.145  23.705  1.00 40.85  ? 377 GLU B CB  1 
ATOM   6411  C  CG  . GLU B 1 377 ? 25.574  14.455  22.384  1.00 43.82  ? 377 GLU B CG  1 
ATOM   6412  C  CD  . GLU B 1 377 ? 25.525  12.942  22.458  1.00 51.10  ? 377 GLU B CD  1 
ATOM   6413  O  OE1 . GLU B 1 377 ? 24.766  12.338  21.663  1.00 53.15  ? 377 GLU B OE1 1 
ATOM   6414  O  OE2 . GLU B 1 377 ? 26.272  12.357  23.278  1.00 60.74  ? 377 GLU B OE2 1 
ATOM   6415  N  N   . GLU B 1 378 ? 27.669  17.954  24.724  1.00 37.76  ? 378 GLU B N   1 
ATOM   6416  C  CA  . GLU B 1 378 ? 28.137  18.823  25.796  1.00 40.81  ? 378 GLU B CA  1 
ATOM   6417  C  C   . GLU B 1 378 ? 28.091  20.285  25.397  1.00 40.18  ? 378 GLU B C   1 
ATOM   6418  O  O   . GLU B 1 378 ? 28.795  21.106  25.991  1.00 37.70  ? 378 GLU B O   1 
ATOM   6419  C  CB  . GLU B 1 378 ? 29.549  18.435  26.235  1.00 43.63  ? 378 GLU B CB  1 
ATOM   6420  C  CG  . GLU B 1 378 ? 29.551  17.377  27.328  1.00 49.97  ? 378 GLU B CG  1 
ATOM   6421  C  CD  . GLU B 1 378 ? 28.972  16.070  26.828  1.00 57.38  ? 378 GLU B CD  1 
ATOM   6422  O  OE1 . GLU B 1 378 ? 29.309  15.689  25.677  1.00 48.93  ? 378 GLU B OE1 1 
ATOM   6423  O  OE2 . GLU B 1 378 ? 28.177  15.432  27.566  1.00 61.76  ? 378 GLU B OE2 1 
ATOM   6424  N  N   . LEU B 1 379 ? 27.267  20.616  24.401  1.00 35.39  ? 379 LEU B N   1 
ATOM   6425  C  CA  . LEU B 1 379 ? 27.019  21.992  23.974  1.00 32.29  ? 379 LEU B CA  1 
ATOM   6426  C  C   . LEU B 1 379 ? 28.287  22.651  23.446  1.00 33.31  ? 379 LEU B C   1 
ATOM   6427  O  O   . LEU B 1 379 ? 28.488  23.854  23.612  1.00 30.80  ? 379 LEU B O   1 
ATOM   6428  C  CB  . LEU B 1 379 ? 26.394  22.828  25.091  1.00 31.11  ? 379 LEU B CB  1 
ATOM   6429  C  CG  . LEU B 1 379 ? 24.952  22.480  25.449  1.00 29.20  ? 379 LEU B CG  1 
ATOM   6430  C  CD1 . LEU B 1 379 ? 24.332  23.616  26.222  1.00 22.58  ? 379 LEU B CD1 1 
ATOM   6431  C  CD2 . LEU B 1 379 ? 24.122  22.140  24.189  1.00 25.57  ? 379 LEU B CD2 1 
ATOM   6432  N  N   . ASP B 1 380 ? 29.129  21.845  22.803  1.00 33.36  ? 380 ASP B N   1 
ATOM   6433  C  CA  . ASP B 1 380 ? 30.356  22.298  22.155  1.00 36.78  ? 380 ASP B CA  1 
ATOM   6434  C  C   . ASP B 1 380 ? 30.042  22.582  20.690  1.00 35.71  ? 380 ASP B C   1 
ATOM   6435  O  O   . ASP B 1 380 ? 29.769  21.654  19.917  1.00 34.82  ? 380 ASP B O   1 
ATOM   6436  C  CB  . ASP B 1 380 ? 31.434  21.222  22.292  1.00 33.58  ? 380 ASP B CB  1 
ATOM   6437  C  CG  . ASP B 1 380 ? 32.779  21.652  21.726  1.00 39.66  ? 380 ASP B CG  1 
ATOM   6438  O  OD1 . ASP B 1 380 ? 33.132  22.846  21.840  1.00 45.44  ? 380 ASP B OD1 1 
ATOM   6439  O  OD2 . ASP B 1 380 ? 33.495  20.782  21.186  1.00 42.99  ? 380 ASP B OD2 1 
ATOM   6440  N  N   . ASP B 1 381 ? 30.031  23.856  20.312  1.00 33.68  ? 381 ASP B N   1 
ATOM   6441  C  CA  . ASP B 1 381 ? 29.884  24.216  18.904  1.00 34.33  ? 381 ASP B CA  1 
ATOM   6442  C  C   . ASP B 1 381 ? 31.232  24.091  18.202  1.00 38.89  ? 381 ASP B C   1 
ATOM   6443  O  O   . ASP B 1 381 ? 32.204  24.745  18.591  1.00 41.44  ? 381 ASP B O   1 
ATOM   6444  C  CB  . ASP B 1 381 ? 29.343  25.631  18.740  1.00 33.53  ? 381 ASP B CB  1 
ATOM   6445  C  CG  . ASP B 1 381 ? 29.035  25.962  17.291  1.00 37.00  ? 381 ASP B CG  1 
ATOM   6446  O  OD1 . ASP B 1 381 ? 29.811  25.560  16.405  1.00 36.57  ? 381 ASP B OD1 1 
ATOM   6447  O  OD2 . ASP B 1 381 ? 27.997  26.599  17.021  1.00 32.78  ? 381 ASP B OD2 1 
ATOM   6448  N  N   . LYS B 1 382 ? 31.268  23.308  17.130  1.00 38.80  ? 382 LYS B N   1 
ATOM   6449  C  CA  . LYS B 1 382 ? 32.520  22.940  16.491  1.00 39.58  ? 382 LYS B CA  1 
ATOM   6450  C  C   . LYS B 1 382 ? 33.022  23.974  15.491  1.00 38.32  ? 382 LYS B C   1 
ATOM   6451  O  O   . LYS B 1 382 ? 34.100  23.781  14.924  1.00 43.59  ? 382 LYS B O   1 
ATOM   6452  C  CB  . LYS B 1 382 ? 32.359  21.590  15.805  1.00 39.30  ? 382 LYS B CB  1 
ATOM   6453  C  CG  . LYS B 1 382 ? 31.747  20.525  16.706  1.00 40.91  ? 382 LYS B CG  1 
ATOM   6454  C  CD  . LYS B 1 382 ? 32.730  20.083  17.778  1.00 40.61  ? 382 LYS B CD  1 
ATOM   6455  C  CE  . LYS B 1 382 ? 32.199  18.892  18.568  1.00 39.51  ? 382 LYS B CE  1 
ATOM   6456  N  NZ  . LYS B 1 382 ? 32.698  18.937  19.972  1.00 44.64  ? 382 LYS B NZ  1 
ATOM   6457  N  N   . GLN B 1 383 ? 32.297  25.066  15.268  1.00 37.67  ? 383 GLN B N   1 
ATOM   6458  C  CA  . GLN B 1 383 ? 32.725  26.018  14.250  1.00 38.96  ? 383 GLN B CA  1 
ATOM   6459  C  C   . GLN B 1 383 ? 32.692  27.457  14.740  1.00 38.24  ? 383 GLN B C   1 
ATOM   6460  O  O   . GLN B 1 383 ? 33.499  28.281  14.302  1.00 37.96  ? 383 GLN B O   1 
ATOM   6461  C  CB  . GLN B 1 383 ? 31.854  25.894  12.997  1.00 33.45  ? 383 GLN B CB  1 
ATOM   6462  C  CG  . GLN B 1 383 ? 32.315  24.842  11.985  1.00 35.52  ? 383 GLN B CG  1 
ATOM   6463  C  CD  . GLN B 1 383 ? 31.897  23.438  12.375  1.00 42.06  ? 383 GLN B CD  1 
ATOM   6464  O  OE1 . GLN B 1 383 ? 30.788  23.215  12.883  1.00 34.19  ? 383 GLN B OE1 1 
ATOM   6465  N  NE2 . GLN B 1 383 ? 32.785  22.476  12.137  1.00 43.80  ? 383 GLN B NE2 1 
ATOM   6466  N  N   . ILE B 1 384 ? 31.759  27.780  15.627  1.00 38.66  ? 384 ILE B N   1 
ATOM   6467  C  CA  . ILE B 1 384 ? 31.441  29.183  15.866  1.00 36.78  ? 384 ILE B CA  1 
ATOM   6468  C  C   . ILE B 1 384 ? 31.814  29.581  17.287  1.00 38.27  ? 384 ILE B C   1 
ATOM   6469  O  O   . ILE B 1 384 ? 31.200  29.109  18.247  1.00 38.49  ? 384 ILE B O   1 
ATOM   6470  C  CB  . ILE B 1 384 ? 29.961  29.467  15.593  1.00 32.63  ? 384 ILE B CB  1 
ATOM   6471  C  CG1 . ILE B 1 384 ? 29.586  28.941  14.225  1.00 36.35  ? 384 ILE B CG1 1 
ATOM   6472  C  CG2 . ILE B 1 384 ? 29.689  30.957  15.671  1.00 34.55  ? 384 ILE B CG2 1 
ATOM   6473  C  CD1 . ILE B 1 384 ? 30.366  29.578  13.095  1.00 37.57  ? 384 ILE B CD1 1 
ATOM   6474  N  N   . PRO B 1 385 ? 32.795  30.438  17.465  1.00 42.83  ? 385 PRO B N   1 
ATOM   6475  C  CA  . PRO B 1 385 ? 33.163  30.865  18.821  1.00 38.34  ? 385 PRO B CA  1 
ATOM   6476  C  C   . PRO B 1 385 ? 32.079  31.729  19.439  1.00 35.23  ? 385 PRO B C   1 
ATOM   6477  O  O   . PRO B 1 385 ? 32.127  32.953  19.317  1.00 39.67  ? 385 PRO B O   1 
ATOM   6478  C  CB  . PRO B 1 385 ? 34.460  31.652  18.592  1.00 39.78  ? 385 PRO B CB  1 
ATOM   6479  C  CG  . PRO B 1 385 ? 34.349  32.139  17.176  1.00 38.52  ? 385 PRO B CG  1 
ATOM   6480  C  CD  . PRO B 1 385 ? 33.617  31.076  16.423  1.00 40.37  ? 385 PRO B CD  1 
ATOM   6481  N  N   . TRP B 1 386 ? 31.101  31.116  20.112  1.00 35.03  ? 386 TRP B N   1 
ATOM   6482  C  CA  . TRP B 1 386 ? 29.917  31.867  20.524  1.00 32.55  ? 386 TRP B CA  1 
ATOM   6483  C  C   . TRP B 1 386 ? 30.226  32.833  21.661  1.00 30.47  ? 386 TRP B C   1 
ATOM   6484  O  O   . TRP B 1 386 ? 29.719  33.962  21.678  1.00 29.64  ? 386 TRP B O   1 
ATOM   6485  C  CB  . TRP B 1 386 ? 28.776  30.901  20.904  1.00 32.62  ? 386 TRP B CB  1 
ATOM   6486  C  CG  . TRP B 1 386 ? 28.114  30.326  19.691  1.00 29.45  ? 386 TRP B CG  1 
ATOM   6487  C  CD1 . TRP B 1 386 ? 28.201  29.045  19.246  1.00 29.89  ? 386 TRP B CD1 1 
ATOM   6488  C  CD2 . TRP B 1 386 ? 27.326  31.040  18.716  1.00 31.79  ? 386 TRP B CD2 1 
ATOM   6489  N  NE1 . TRP B 1 386 ? 27.492  28.903  18.074  1.00 32.76  ? 386 TRP B NE1 1 
ATOM   6490  C  CE2 . TRP B 1 386 ? 26.956  30.113  17.722  1.00 31.99  ? 386 TRP B CE2 1 
ATOM   6491  C  CE3 . TRP B 1 386 ? 26.904  32.363  18.590  1.00 25.53  ? 386 TRP B CE3 1 
ATOM   6492  C  CZ2 . TRP B 1 386 ? 26.182  30.468  16.617  1.00 26.08  ? 386 TRP B CZ2 1 
ATOM   6493  C  CZ3 . TRP B 1 386 ? 26.136  32.713  17.497  1.00 27.13  ? 386 TRP B CZ3 1 
ATOM   6494  C  CH2 . TRP B 1 386 ? 25.786  31.768  16.522  1.00 31.66  ? 386 TRP B CH2 1 
ATOM   6495  N  N   . GLU B 1 387 ? 31.047  32.421  22.620  1.00 33.76  ? 387 GLU B N   1 
ATOM   6496  C  CA  . GLU B 1 387 ? 31.297  33.303  23.757  1.00 37.00  ? 387 GLU B CA  1 
ATOM   6497  C  C   . GLU B 1 387 ? 31.885  34.653  23.358  1.00 34.40  ? 387 GLU B C   1 
ATOM   6498  O  O   . GLU B 1 387 ? 31.333  35.681  23.785  1.00 38.81  ? 387 GLU B O   1 
ATOM   6499  C  CB  . GLU B 1 387 ? 32.168  32.604  24.795  1.00 39.51  ? 387 GLU B CB  1 
ATOM   6500  C  CG  . GLU B 1 387 ? 32.342  33.511  25.986  1.00 45.73  ? 387 GLU B CG  1 
ATOM   6501  C  CD  . GLU B 1 387 ? 32.643  32.750  27.228  1.00 55.80  ? 387 GLU B CD  1 
ATOM   6502  O  OE1 . GLU B 1 387 ? 32.561  31.496  27.166  1.00 56.92  ? 387 GLU B OE1 1 
ATOM   6503  O  OE2 . GLU B 1 387 ? 32.955  33.405  28.256  1.00 55.50  ? 387 GLU B OE2 1 
ATOM   6504  N  N   . PRO B 1 388 ? 32.957  34.746  22.553  1.00 34.92  ? 388 PRO B N   1 
ATOM   6505  C  CA  . PRO B 1 388 ? 33.424  36.088  22.144  1.00 36.30  ? 388 PRO B CA  1 
ATOM   6506  C  C   . PRO B 1 388 ? 32.483  36.795  21.182  1.00 35.11  ? 388 PRO B C   1 
ATOM   6507  O  O   . PRO B 1 388 ? 32.391  38.029  21.224  1.00 35.55  ? 388 PRO B O   1 
ATOM   6508  C  CB  . PRO B 1 388 ? 34.790  35.814  21.496  1.00 36.75  ? 388 PRO B CB  1 
ATOM   6509  C  CG  . PRO B 1 388 ? 34.757  34.393  21.098  1.00 35.17  ? 388 PRO B CG  1 
ATOM   6510  C  CD  . PRO B 1 388 ? 33.887  33.690  22.110  1.00 36.22  ? 388 PRO B CD  1 
ATOM   6511  N  N   . VAL B 1 389 ? 31.796  36.057  20.301  1.00 35.13  ? 389 VAL B N   1 
ATOM   6512  C  CA  . VAL B 1 389 ? 30.787  36.672  19.438  1.00 28.74  ? 389 VAL B CA  1 
ATOM   6513  C  C   . VAL B 1 389 ? 29.689  37.286  20.280  1.00 32.94  ? 389 VAL B C   1 
ATOM   6514  O  O   . VAL B 1 389 ? 29.227  38.404  20.021  1.00 35.09  ? 389 VAL B O   1 
ATOM   6515  C  CB  . VAL B 1 389 ? 30.201  35.631  18.464  1.00 32.43  ? 389 VAL B CB  1 
ATOM   6516  C  CG1 . VAL B 1 389 ? 28.943  36.184  17.801  1.00 33.18  ? 389 VAL B CG1 1 
ATOM   6517  C  CG2 . VAL B 1 389 ? 31.207  35.214  17.443  1.00 27.46  ? 389 VAL B CG2 1 
ATOM   6518  N  N   . LEU B 1 390 ? 29.223  36.538  21.282  1.00 31.04  ? 390 LEU B N   1 
ATOM   6519  C  CA  . LEU B 1 390 ? 28.101  37.001  22.082  1.00 31.99  ? 390 LEU B CA  1 
ATOM   6520  C  C   . LEU B 1 390 ? 28.533  38.115  23.020  1.00 33.84  ? 390 LEU B C   1 
ATOM   6521  O  O   . LEU B 1 390 ? 27.771  39.057  23.261  1.00 35.04  ? 390 LEU B O   1 
ATOM   6522  C  CB  . LEU B 1 390 ? 27.488  35.830  22.868  1.00 34.88  ? 390 LEU B CB  1 
ATOM   6523  C  CG  . LEU B 1 390 ? 26.697  34.747  22.095  1.00 31.77  ? 390 LEU B CG  1 
ATOM   6524  C  CD1 . LEU B 1 390 ? 26.163  33.662  23.039  1.00 34.98  ? 390 LEU B CD1 1 
ATOM   6525  C  CD2 . LEU B 1 390 ? 25.558  35.337  21.292  1.00 29.10  ? 390 LEU B CD2 1 
ATOM   6526  N  N   . LYS B 1 391 ? 29.754  38.029  23.562  1.00 38.98  ? 391 LYS B N   1 
ATOM   6527  C  CA  . LYS B 1 391 ? 30.242  39.095  24.434  1.00 35.87  ? 391 LYS B CA  1 
ATOM   6528  C  C   . LYS B 1 391 ? 30.435  40.392  23.654  1.00 34.36  ? 391 LYS B C   1 
ATOM   6529  O  O   . LYS B 1 391 ? 30.038  41.474  24.116  1.00 36.47  ? 391 LYS B O   1 
ATOM   6530  C  CB  . LYS B 1 391 ? 31.540  38.664  25.109  1.00 37.78  ? 391 LYS B CB  1 
ATOM   6531  C  CG  . LYS B 1 391 ? 32.312  39.791  25.752  1.00 41.87  ? 391 LYS B CG  1 
ATOM   6532  C  CD  . LYS B 1 391 ? 33.662  39.328  26.270  1.00 46.75  ? 391 LYS B CD  1 
ATOM   6533  C  CE  . LYS B 1 391 ? 34.067  40.120  27.518  1.00 47.50  ? 391 LYS B CE  1 
ATOM   6534  N  NZ  . LYS B 1 391 ? 33.220  41.332  27.741  1.00 50.84  ? 391 LYS B NZ  1 
ATOM   6535  N  N   . ALA B 1 392 ? 31.018  40.303  22.462  1.00 35.65  ? 392 ALA B N   1 
ATOM   6536  C  CA  . ALA B 1 392 ? 31.139  41.492  21.628  1.00 34.42  ? 392 ALA B CA  1 
ATOM   6537  C  C   . ALA B 1 392 ? 29.767  42.081  21.339  1.00 37.27  ? 392 ALA B C   1 
ATOM   6538  O  O   . ALA B 1 392 ? 29.567  43.293  21.465  1.00 39.84  ? 392 ALA B O   1 
ATOM   6539  C  CB  . ALA B 1 392 ? 31.872  41.147  20.336  1.00 34.25  ? 392 ALA B CB  1 
ATOM   6540  N  N   . LEU B 1 393 ? 28.789  41.229  21.006  1.00 37.52  ? 393 LEU B N   1 
ATOM   6541  C  CA  . LEU B 1 393 ? 27.458  41.731  20.673  1.00 35.86  ? 393 LEU B CA  1 
ATOM   6542  C  C   . LEU B 1 393 ? 26.805  42.422  21.868  1.00 33.81  ? 393 LEU B C   1 
ATOM   6543  O  O   . LEU B 1 393 ? 26.116  43.438  21.711  1.00 35.07  ? 393 LEU B O   1 
ATOM   6544  C  CB  . LEU B 1 393 ? 26.585  40.586  20.158  1.00 34.18  ? 393 LEU B CB  1 
ATOM   6545  C  CG  . LEU B 1 393 ? 26.860  40.154  18.710  1.00 32.68  ? 393 LEU B CG  1 
ATOM   6546  C  CD1 . LEU B 1 393 ? 26.124  38.881  18.388  1.00 41.13  ? 393 LEU B CD1 1 
ATOM   6547  C  CD2 . LEU B 1 393 ? 26.483  41.266  17.740  1.00 29.30  ? 393 LEU B CD2 1 
ATOM   6548  N  N   . LYS B 1 394 ? 27.001  41.877  23.068  1.00 40.47  ? 394 LYS B N   1 
ATOM   6549  C  CA  . LYS B 1 394 ? 26.429  42.479  24.271  1.00 41.41  ? 394 LYS B CA  1 
ATOM   6550  C  C   . LYS B 1 394 ? 27.101  43.805  24.594  1.00 39.87  ? 394 LYS B C   1 
ATOM   6551  O  O   . LYS B 1 394 ? 26.428  44.798  24.886  1.00 44.82  ? 394 LYS B O   1 
ATOM   6552  C  CB  . LYS B 1 394 ? 26.562  41.519  25.454  1.00 40.10  ? 394 LYS B CB  1 
ATOM   6553  C  CG  . LYS B 1 394 ? 25.780  41.928  26.699  1.00 40.61  ? 394 LYS B CG  1 
ATOM   6554  C  CD  . LYS B 1 394 ? 26.043  40.944  27.837  1.00 46.28  ? 394 LYS B CD  1 
ATOM   6555  C  CE  . LYS B 1 394 ? 26.045  41.607  29.227  1.00 49.13  ? 394 LYS B CE  1 
ATOM   6556  N  NZ  . LYS B 1 394 ? 24.723  41.517  29.919  1.00 42.64  ? 394 LYS B NZ  1 
ATOM   6557  N  N   . ASP B 1 395 ? 28.433  43.835  24.571  1.00 44.97  ? 395 ASP B N   1 
ATOM   6558  C  CA  . ASP B 1 395 ? 29.139  45.074  24.882  1.00 39.45  ? 395 ASP B CA  1 
ATOM   6559  C  C   . ASP B 1 395 ? 28.891  46.143  23.824  1.00 40.64  ? 395 ASP B C   1 
ATOM   6560  O  O   . ASP B 1 395 ? 28.893  47.336  24.146  1.00 44.65  ? 395 ASP B O   1 
ATOM   6561  C  CB  . ASP B 1 395 ? 30.633  44.797  25.056  1.00 37.57  ? 395 ASP B CB  1 
ATOM   6562  C  CG  . ASP B 1 395 ? 30.920  43.912  26.257  1.00 43.09  ? 395 ASP B CG  1 
ATOM   6563  O  OD1 . ASP B 1 395 ? 30.016  43.786  27.109  1.00 50.97  ? 395 ASP B OD1 1 
ATOM   6564  O  OD2 . ASP B 1 395 ? 32.030  43.340  26.354  1.00 41.99  ? 395 ASP B OD2 1 
ATOM   6565  N  N   . ALA B 1 396 ? 28.633  45.747  22.575  1.00 39.93  ? 396 ALA B N   1 
ATOM   6566  C  CA  . ALA B 1 396 ? 28.303  46.723  21.542  1.00 39.27  ? 396 ALA B CA  1 
ATOM   6567  C  C   . ALA B 1 396 ? 26.875  47.248  21.633  1.00 40.08  ? 396 ALA B C   1 
ATOM   6568  O  O   . ALA B 1 396 ? 26.535  48.177  20.892  1.00 44.25  ? 396 ALA B O   1 
ATOM   6569  C  CB  . ALA B 1 396 ? 28.539  46.131  20.155  1.00 39.28  ? 396 ALA B CB  1 
ATOM   6570  N  N   . GLY B 1 397 ? 26.038  46.685  22.503  1.00 38.85  ? 397 GLY B N   1 
ATOM   6571  C  CA  . GLY B 1 397 ? 24.690  47.182  22.695  1.00 34.32  ? 397 GLY B CA  1 
ATOM   6572  C  C   . GLY B 1 397 ? 23.596  46.507  21.890  1.00 37.98  ? 397 GLY B C   1 
ATOM   6573  O  O   . GLY B 1 397 ? 22.489  47.052  21.809  1.00 35.94  ? 397 GLY B O   1 
ATOM   6574  N  N   . TYR B 1 398 ? 23.848  45.335  21.312  1.00 36.16  ? 398 TYR B N   1 
ATOM   6575  C  CA  . TYR B 1 398 ? 22.847  44.683  20.472  1.00 39.68  ? 398 TYR B CA  1 
ATOM   6576  C  C   . TYR B 1 398 ? 21.770  44.038  21.340  1.00 33.92  ? 398 TYR B C   1 
ATOM   6577  O  O   . TYR B 1 398 ? 22.068  43.196  22.192  1.00 41.00  ? 398 TYR B O   1 
ATOM   6578  C  CB  . TYR B 1 398 ? 23.497  43.639  19.559  1.00 38.43  ? 398 TYR B CB  1 
ATOM   6579  C  CG  . TYR B 1 398 ? 22.518  42.961  18.614  1.00 32.65  ? 398 TYR B CG  1 
ATOM   6580  C  CD1 . TYR B 1 398 ? 22.045  43.613  17.490  1.00 32.11  ? 398 TYR B CD1 1 
ATOM   6581  C  CD2 . TYR B 1 398 ? 22.065  41.667  18.854  1.00 36.52  ? 398 TYR B CD2 1 
ATOM   6582  C  CE1 . TYR B 1 398 ? 21.157  43.000  16.622  1.00 35.15  ? 398 TYR B CE1 1 
ATOM   6583  C  CE2 . TYR B 1 398 ? 21.170  41.051  17.997  1.00 29.99  ? 398 TYR B CE2 1 
ATOM   6584  C  CZ  . TYR B 1 398 ? 20.717  41.713  16.886  1.00 36.02  ? 398 TYR B CZ  1 
ATOM   6585  O  OH  . TYR B 1 398 ? 19.824  41.086  16.030  1.00 33.52  ? 398 TYR B OH  1 
ATOM   6586  N  N   . THR B 1 399 ? 20.517  44.427  21.122  1.00 34.75  ? 399 THR B N   1 
ATOM   6587  C  CA  . THR B 1 399 ? 19.393  43.848  21.849  1.00 38.86  ? 399 THR B CA  1 
ATOM   6588  C  C   . THR B 1 399 ? 18.367  43.211  20.909  1.00 40.32  ? 399 THR B C   1 
ATOM   6589  O  O   . THR B 1 399 ? 17.213  43.004  21.304  1.00 43.35  ? 399 THR B O   1 
ATOM   6590  C  CB  . THR B 1 399 ? 18.723  44.907  22.738  1.00 43.12  ? 399 THR B CB  1 
ATOM   6591  O  OG1 . THR B 1 399 ? 18.348  46.045  21.948  1.00 42.15  ? 399 THR B OG1 1 
ATOM   6592  C  CG2 . THR B 1 399 ? 19.665  45.364  23.883  1.00 33.79  ? 399 THR B CG2 1 
ATOM   6593  N  N   . GLY B 1 400 ? 18.760  42.888  19.674  1.00 37.40  ? 400 GLY B N   1 
ATOM   6594  C  CA  . GLY B 1 400 ? 17.856  42.325  18.689  1.00 35.06  ? 400 GLY B CA  1 
ATOM   6595  C  C   . GLY B 1 400 ? 17.812  40.808  18.698  1.00 32.18  ? 400 GLY B C   1 
ATOM   6596  O  O   . GLY B 1 400 ? 18.176  40.145  19.673  1.00 35.54  ? 400 GLY B O   1 
ATOM   6597  N  N   . TYR B 1 401 ? 17.398  40.253  17.563  1.00 33.26  ? 401 TYR B N   1 
ATOM   6598  C  CA  . TYR B 1 401 ? 17.147  38.823  17.426  1.00 28.89  ? 401 TYR B CA  1 
ATOM   6599  C  C   . TYR B 1 401 ? 18.412  38.088  17.007  1.00 32.75  ? 401 TYR B C   1 
ATOM   6600  O  O   . TYR B 1 401 ? 19.246  38.627  16.271  1.00 33.81  ? 401 TYR B O   1 
ATOM   6601  C  CB  . TYR B 1 401 ? 16.045  38.580  16.388  1.00 28.17  ? 401 TYR B CB  1 
ATOM   6602  C  CG  . TYR B 1 401 ? 14.651  38.456  16.953  1.00 27.54  ? 401 TYR B CG  1 
ATOM   6603  C  CD1 . TYR B 1 401 ? 14.223  37.259  17.512  1.00 28.38  ? 401 TYR B CD1 1 
ATOM   6604  C  CD2 . TYR B 1 401 ? 13.768  39.533  16.941  1.00 31.12  ? 401 TYR B CD2 1 
ATOM   6605  C  CE1 . TYR B 1 401 ? 12.953  37.119  18.023  1.00 25.21  ? 401 TYR B CE1 1 
ATOM   6606  C  CE2 . TYR B 1 401 ? 12.485  39.413  17.462  1.00 31.42  ? 401 TYR B CE2 1 
ATOM   6607  C  CZ  . TYR B 1 401 ? 12.086  38.190  18.006  1.00 33.93  ? 401 TYR B CZ  1 
ATOM   6608  O  OH  . TYR B 1 401 ? 10.825  38.011  18.546  1.00 29.94  ? 401 TYR B OH  1 
ATOM   6609  N  N   . LEU B 1 402 ? 18.548  36.849  17.491  1.00 27.19  ? 402 LEU B N   1 
ATOM   6610  C  CA  . LEU B 1 402 ? 19.510  35.881  16.971  1.00 28.72  ? 402 LEU B CA  1 
ATOM   6611  C  C   . LEU B 1 402 ? 18.700  34.728  16.396  1.00 28.46  ? 402 LEU B C   1 
ATOM   6612  O  O   . LEU B 1 402 ? 18.144  33.922  17.142  1.00 29.55  ? 402 LEU B O   1 
ATOM   6613  C  CB  . LEU B 1 402 ? 20.472  35.381  18.049  1.00 29.84  ? 402 LEU B CB  1 
ATOM   6614  C  CG  . LEU B 1 402 ? 21.386  36.325  18.833  1.00 32.89  ? 402 LEU B CG  1 
ATOM   6615  C  CD1 . LEU B 1 402 ? 22.191  35.504  19.833  1.00 34.71  ? 402 LEU B CD1 1 
ATOM   6616  C  CD2 . LEU B 1 402 ? 22.319  37.155  17.938  1.00 31.31  ? 402 LEU B CD2 1 
ATOM   6617  N  N   . SER B 1 403 ? 18.640  34.643  15.081  1.00 29.64  ? 403 SER B N   1 
ATOM   6618  C  CA  . SER B 1 403 ? 17.711  33.757  14.389  1.00 31.76  ? 403 SER B CA  1 
ATOM   6619  C  C   . SER B 1 403 ? 18.457  32.518  13.908  1.00 31.30  ? 403 SER B C   1 
ATOM   6620  O  O   . SER B 1 403 ? 19.321  32.605  13.031  1.00 23.08  ? 403 SER B O   1 
ATOM   6621  C  CB  . SER B 1 403 ? 17.074  34.498  13.218  1.00 28.74  ? 403 SER B CB  1 
ATOM   6622  O  OG  . SER B 1 403 ? 15.814  33.981  12.900  1.00 32.30  ? 403 SER B OG  1 
ATOM   6623  N  N   . SER B 1 404 ? 18.098  31.364  14.457  1.00 24.23  ? 404 SER B N   1 
ATOM   6624  C  CA  . SER B 1 404 ? 18.804  30.133  14.154  1.00 21.92  ? 404 SER B CA  1 
ATOM   6625  C  C   . SER B 1 404 ? 18.843  29.869  12.656  1.00 26.37  ? 404 SER B C   1 
ATOM   6626  O  O   . SER B 1 404 ? 17.828  30.000  11.966  1.00 27.78  ? 404 SER B O   1 
ATOM   6627  C  CB  . SER B 1 404 ? 18.111  28.971  14.865  1.00 26.22  ? 404 SER B CB  1 
ATOM   6628  O  OG  . SER B 1 404 ? 18.159  29.157  16.262  1.00 32.64  ? 404 SER B OG  1 
ATOM   6629  N  N   . GLU B 1 405 ? 20.037  29.491  12.147  1.00 28.71  ? 405 GLU B N   1 
ATOM   6630  C  CA  . GLU B 1 405 ? 20.202  29.026  10.759  1.00 27.13  ? 405 GLU B CA  1 
ATOM   6631  C  C   . GLU B 1 405 ? 21.119  27.800  10.815  1.00 26.49  ? 405 GLU B C   1 
ATOM   6632  O  O   . GLU B 1 405 ? 22.326  27.868  10.568  1.00 26.33  ? 405 GLU B O   1 
ATOM   6633  C  CB  . GLU B 1 405 ? 20.744  30.125  9.837   1.00 26.84  ? 405 GLU B CB  1 
ATOM   6634  C  CG  . GLU B 1 405 ? 19.673  30.781  8.953   1.00 21.31  ? 405 GLU B CG  1 
ATOM   6635  C  CD  . GLU B 1 405 ? 20.246  31.738  7.887   1.00 31.31  ? 405 GLU B CD  1 
ATOM   6636  O  OE1 . GLU B 1 405 ? 21.478  31.961  7.839   1.00 32.92  ? 405 GLU B OE1 1 
ATOM   6637  O  OE2 . GLU B 1 405 ? 19.459  32.252  7.064   1.00 27.56  ? 405 GLU B OE2 1 
ATOM   6638  N  N   . TYR B 1 406 ? 20.530  26.662  11.182  1.00 26.80  ? 406 TYR B N   1 
ATOM   6639  C  CA  . TYR B 1 406 ? 21.244  25.397  11.129  1.00 25.19  ? 406 TYR B CA  1 
ATOM   6640  C  C   . TYR B 1 406 ? 21.642  25.090  9.692   1.00 26.95  ? 406 TYR B C   1 
ATOM   6641  O  O   . TYR B 1 406 ? 20.819  25.154  8.773   1.00 28.84  ? 406 TYR B O   1 
ATOM   6642  C  CB  . TYR B 1 406 ? 20.386  24.253  11.707  1.00 25.71  ? 406 TYR B CB  1 
ATOM   6643  C  CG  . TYR B 1 406 ? 21.036  22.905  11.502  1.00 26.23  ? 406 TYR B CG  1 
ATOM   6644  C  CD1 . TYR B 1 406 ? 22.192  22.574  12.199  1.00 27.72  ? 406 TYR B CD1 1 
ATOM   6645  C  CD2 . TYR B 1 406 ? 20.530  21.978  10.596  1.00 30.01  ? 406 TYR B CD2 1 
ATOM   6646  C  CE1 . TYR B 1 406 ? 22.819  21.378  12.022  1.00 27.16  ? 406 TYR B CE1 1 
ATOM   6647  C  CE2 . TYR B 1 406 ? 21.165  20.752  10.406  1.00 26.53  ? 406 TYR B CE2 1 
ATOM   6648  C  CZ  . TYR B 1 406 ? 22.314  20.467  11.137  1.00 29.22  ? 406 TYR B CZ  1 
ATOM   6649  O  OH  . TYR B 1 406 ? 22.989  19.275  11.005  1.00 32.39  ? 406 TYR B OH  1 
ATOM   6650  N  N   . GLU B 1 407 ? 22.924  24.791  9.499   1.00 28.07  ? 407 GLU B N   1 
ATOM   6651  C  CA  . GLU B 1 407 ? 23.464  24.481  8.182   1.00 29.08  ? 407 GLU B CA  1 
ATOM   6652  C  C   . GLU B 1 407 ? 24.414  23.309  8.250   1.00 28.59  ? 407 GLU B C   1 
ATOM   6653  O  O   . GLU B 1 407 ? 25.420  23.281  7.535   1.00 29.82  ? 407 GLU B O   1 
ATOM   6654  C  CB  . GLU B 1 407 ? 24.204  25.672  7.581   1.00 32.97  ? 407 GLU B CB  1 
ATOM   6655  C  CG  . GLU B 1 407 ? 23.426  26.375  6.529   1.00 35.55  ? 407 GLU B CG  1 
ATOM   6656  C  CD  . GLU B 1 407 ? 24.300  27.187  5.577   1.00 41.56  ? 407 GLU B CD  1 
ATOM   6657  O  OE1 . GLU B 1 407 ? 25.553  27.073  5.639   1.00 40.46  ? 407 GLU B OE1 1 
ATOM   6658  O  OE2 . GLU B 1 407 ? 23.717  27.948  4.773   1.00 34.49  ? 407 GLU B OE2 1 
ATOM   6659  N  N   . GLY B 1 408 ? 24.160  22.370  9.156   1.00 32.82  ? 408 GLY B N   1 
ATOM   6660  C  CA  . GLY B 1 408 ? 24.949  21.167  9.230   1.00 24.97  ? 408 GLY B CA  1 
ATOM   6661  C  C   . GLY B 1 408 ? 24.415  20.123  8.276   1.00 32.56  ? 408 GLY B C   1 
ATOM   6662  O  O   . GLY B 1 408 ? 23.597  20.392  7.394   1.00 30.18  ? 408 GLY B O   1 
ATOM   6663  N  N   . GLU B 1 409 ? 24.889  18.900  8.477   1.00 31.89  ? 409 GLU B N   1 
ATOM   6664  C  CA  . GLU B 1 409 ? 24.430  17.768  7.695   1.00 34.94  ? 409 GLU B CA  1 
ATOM   6665  C  C   . GLU B 1 409 ? 22.910  17.671  7.768   1.00 29.06  ? 409 GLU B C   1 
ATOM   6666  O  O   . GLU B 1 409 ? 22.315  17.778  8.848   1.00 29.70  ? 409 GLU B O   1 
ATOM   6667  C  CB  . GLU B 1 409 ? 25.110  16.499  8.221   1.00 41.56  ? 409 GLU B CB  1 
ATOM   6668  C  CG  . GLU B 1 409 ? 24.491  15.168  7.818   1.00 49.01  ? 409 GLU B CG  1 
ATOM   6669  C  CD  . GLU B 1 409 ? 25.359  13.989  8.249   1.00 58.28  ? 409 GLU B CD  1 
ATOM   6670  O  OE1 . GLU B 1 409 ? 26.490  14.243  8.723   1.00 67.16  ? 409 GLU B OE1 1 
ATOM   6671  O  OE2 . GLU B 1 409 ? 24.937  12.819  8.080   1.00 57.32  ? 409 GLU B OE2 1 
ATOM   6672  N  N   . ARG B 1 410 ? 22.283  17.530  6.606   1.00 28.91  ? 410 ARG B N   1 
ATOM   6673  C  CA  . ARG B 1 410 ? 20.823  17.445  6.508   1.00 30.32  ? 410 ARG B CA  1 
ATOM   6674  C  C   . ARG B 1 410 ? 20.321  16.017  6.694   1.00 27.07  ? 410 ARG B C   1 
ATOM   6675  O  O   . ARG B 1 410 ? 19.511  15.527  5.908   1.00 32.66  ? 410 ARG B O   1 
ATOM   6676  C  CB  . ARG B 1 410 ? 20.359  18.007  5.175   1.00 26.31  ? 410 ARG B CB  1 
ATOM   6677  C  CG  . ARG B 1 410 ? 20.834  19.428  4.916   1.00 27.21  ? 410 ARG B CG  1 
ATOM   6678  C  CD  . ARG B 1 410 ? 20.125  20.411  5.780   1.00 26.42  ? 410 ARG B CD  1 
ATOM   6679  N  NE  . ARG B 1 410 ? 20.487  21.769  5.395   1.00 31.48  ? 410 ARG B NE  1 
ATOM   6680  C  CZ  . ARG B 1 410 ? 20.301  22.839  6.151   1.00 26.35  ? 410 ARG B CZ  1 
ATOM   6681  N  NH1 . ARG B 1 410 ? 19.742  22.752  7.337   1.00 29.10  ? 410 ARG B NH1 1 
ATOM   6682  N  NH2 . ARG B 1 410 ? 20.656  24.032  5.688   1.00 35.61  ? 410 ARG B NH2 1 
ATOM   6683  N  N   . GLU B 1 411 ? 20.797  15.341  7.735   1.00 29.08  ? 411 GLU B N   1 
ATOM   6684  C  CA  . GLU B 1 411 ? 20.198  14.067  8.138   1.00 31.81  ? 411 GLU B CA  1 
ATOM   6685  C  C   . GLU B 1 411 ? 18.751  14.299  8.564   1.00 30.48  ? 411 GLU B C   1 
ATOM   6686  O  O   . GLU B 1 411 ? 18.480  15.230  9.338   1.00 31.71  ? 411 GLU B O   1 
ATOM   6687  C  CB  . GLU B 1 411 ? 20.963  13.435  9.305   1.00 31.88  ? 411 GLU B CB  1 
ATOM   6688  C  CG  . GLU B 1 411 ? 22.040  12.467  8.905   1.00 43.91  ? 411 GLU B CG  1 
ATOM   6689  C  CD  . GLU B 1 411 ? 21.765  11.793  7.569   1.00 54.80  ? 411 GLU B CD  1 
ATOM   6690  O  OE1 . GLU B 1 411 ? 21.044  10.765  7.544   1.00 59.30  ? 411 GLU B OE1 1 
ATOM   6691  O  OE2 . GLU B 1 411 ? 22.282  12.290  6.539   1.00 55.06  ? 411 GLU B OE2 1 
ATOM   6692  N  N   . PRO B 1 412 ? 17.806  13.480  8.113   1.00 29.89  ? 412 PRO B N   1 
ATOM   6693  C  CA  . PRO B 1 412 ? 16.414  13.663  8.541   1.00 26.53  ? 412 PRO B CA  1 
ATOM   6694  C  C   . PRO B 1 412 ? 16.321  13.834  10.049  1.00 22.57  ? 412 PRO B C   1 
ATOM   6695  O  O   . PRO B 1 412 ? 16.944  13.096  10.820  1.00 27.13  ? 412 PRO B O   1 
ATOM   6696  C  CB  . PRO B 1 412 ? 15.723  12.383  8.054   1.00 24.84  ? 412 PRO B CB  1 
ATOM   6697  C  CG  . PRO B 1 412 ? 16.585  11.908  6.922   1.00 32.58  ? 412 PRO B CG  1 
ATOM   6698  C  CD  . PRO B 1 412 ? 17.989  12.276  7.287   1.00 31.98  ? 412 PRO B CD  1 
ATOM   6699  N  N   . TRP B 1 413 ? 15.611  14.883  10.455  1.00 28.58  ? 413 TRP B N   1 
ATOM   6700  C  CA  . TRP B 1 413 ? 15.318  15.287  11.839  1.00 24.30  ? 413 TRP B CA  1 
ATOM   6701  C  C   . TRP B 1 413 ? 16.497  15.900  12.592  1.00 23.05  ? 413 TRP B C   1 
ATOM   6702  O  O   . TRP B 1 413 ? 16.285  16.499  13.646  1.00 26.78  ? 413 TRP B O   1 
ATOM   6703  C  CB  . TRP B 1 413 ? 14.736  14.117  12.677  1.00 21.67  ? 413 TRP B CB  1 
ATOM   6704  C  CG  . TRP B 1 413 ? 13.400  13.651  12.176  1.00 23.15  ? 413 TRP B CG  1 
ATOM   6705  C  CD1 . TRP B 1 413 ? 12.166  14.184  12.448  1.00 23.62  ? 413 TRP B CD1 1 
ATOM   6706  C  CD2 . TRP B 1 413 ? 13.178  12.554  11.295  1.00 23.07  ? 413 TRP B CD2 1 
ATOM   6707  N  NE1 . TRP B 1 413 ? 11.180  13.477  11.768  1.00 24.36  ? 413 TRP B NE1 1 
ATOM   6708  C  CE2 . TRP B 1 413 ? 11.785  12.469  11.060  1.00 24.29  ? 413 TRP B CE2 1 
ATOM   6709  C  CE3 . TRP B 1 413 ? 14.017  11.609  10.706  1.00 20.43  ? 413 TRP B CE3 1 
ATOM   6710  C  CZ2 . TRP B 1 413 ? 11.231  11.495  10.239  1.00 23.14  ? 413 TRP B CZ2 1 
ATOM   6711  C  CZ3 . TRP B 1 413 ? 13.465  10.649  9.889   1.00 22.07  ? 413 TRP B CZ3 1 
ATOM   6712  C  CH2 . TRP B 1 413 ? 12.086  10.595  9.660   1.00 23.62  ? 413 TRP B CH2 1 
ATOM   6713  N  N   . ARG B 1 414 ? 17.730  15.784  12.095  1.00 24.15  ? 414 ARG B N   1 
ATOM   6714  C  CA  . ARG B 1 414 ? 18.859  16.260  12.896  1.00 24.17  ? 414 ARG B CA  1 
ATOM   6715  C  C   . ARG B 1 414 ? 18.764  17.742  13.228  1.00 31.44  ? 414 ARG B C   1 
ATOM   6716  O  O   . ARG B 1 414 ? 19.206  18.158  14.308  1.00 30.69  ? 414 ARG B O   1 
ATOM   6717  C  CB  . ARG B 1 414 ? 20.179  15.980  12.197  1.00 28.67  ? 414 ARG B CB  1 
ATOM   6718  C  CG  . ARG B 1 414 ? 21.268  15.711  13.199  1.00 33.48  ? 414 ARG B CG  1 
ATOM   6719  C  CD  . ARG B 1 414 ? 22.568  15.329  12.537  1.00 37.88  ? 414 ARG B CD  1 
ATOM   6720  N  NE  . ARG B 1 414 ? 23.480  16.457  12.505  1.00 36.13  ? 414 ARG B NE  1 
ATOM   6721  C  CZ  . ARG B 1 414 ? 24.439  16.659  13.399  1.00 43.62  ? 414 ARG B CZ  1 
ATOM   6722  N  NH1 . ARG B 1 414 ? 24.646  15.814  14.392  1.00 44.06  ? 414 ARG B NH1 1 
ATOM   6723  N  NH2 . ARG B 1 414 ? 25.204  17.739  13.294  1.00 41.43  ? 414 ARG B NH2 1 
ATOM   6724  N  N   . SER B 1 415 ? 18.195  18.556  12.328  1.00 27.64  ? 415 SER B N   1 
ATOM   6725  C  CA  . SER B 1 415 ? 18.097  19.989  12.591  1.00 26.39  ? 415 SER B CA  1 
ATOM   6726  C  C   . SER B 1 415 ? 17.324  20.298  13.870  1.00 24.84  ? 415 SER B C   1 
ATOM   6727  O  O   . SER B 1 415 ? 17.483  21.380  14.443  1.00 23.17  ? 415 SER B O   1 
ATOM   6728  C  CB  . SER B 1 415 ? 17.415  20.691  11.425  1.00 24.97  ? 415 SER B CB  1 
ATOM   6729  O  OG  . SER B 1 415 ? 16.101  20.193  11.278  1.00 27.52  ? 415 SER B OG  1 
ATOM   6730  N  N   . ILE B 1 416 ? 16.440  19.405  14.311  1.00 28.64  ? 416 ILE B N   1 
ATOM   6731  C  CA  . ILE B 1 416 ? 15.598  19.751  15.451  1.00 23.74  ? 416 ILE B CA  1 
ATOM   6732  C  C   . ILE B 1 416 ? 16.434  19.820  16.727  1.00 24.30  ? 416 ILE B C   1 
ATOM   6733  O  O   . ILE B 1 416 ? 16.431  20.843  17.419  1.00 28.11  ? 416 ILE B O   1 
ATOM   6734  C  CB  . ILE B 1 416 ? 14.429  18.763  15.592  1.00 28.11  ? 416 ILE B CB  1 
ATOM   6735  C  CG1 . ILE B 1 416 ? 13.408  19.015  14.474  1.00 26.44  ? 416 ILE B CG1 1 
ATOM   6736  C  CG2 . ILE B 1 416 ? 13.788  18.962  16.956  1.00 20.03  ? 416 ILE B CG2 1 
ATOM   6737  C  CD1 . ILE B 1 416 ? 12.223  18.061  14.500  1.00 26.54  ? 416 ILE B CD1 1 
ATOM   6738  N  N   . GLU B 1 417 ? 17.141  18.720  17.059  1.00 30.89  ? 417 GLU B N   1 
ATOM   6739  C  CA  . GLU B 1 417 ? 18.053  18.692  18.209  1.00 29.13  ? 417 GLU B CA  1 
ATOM   6740  C  C   . GLU B 1 417 ? 19.105  19.784  18.079  1.00 25.14  ? 417 GLU B C   1 
ATOM   6741  O  O   . GLU B 1 417 ? 19.423  20.481  19.045  1.00 26.32  ? 417 GLU B O   1 
ATOM   6742  C  CB  . GLU B 1 417 ? 18.741  17.322  18.319  1.00 26.63  ? 417 GLU B CB  1 
ATOM   6743  C  CG  . GLU B 1 417 ? 18.256  16.402  19.445  1.00 31.63  ? 417 GLU B CG  1 
ATOM   6744  C  CD  . GLU B 1 417 ? 18.175  17.117  20.773  1.00 31.21  ? 417 GLU B CD  1 
ATOM   6745  O  OE1 . GLU B 1 417 ? 19.232  17.472  21.344  1.00 29.84  ? 417 GLU B OE1 1 
ATOM   6746  O  OE2 . GLU B 1 417 ? 17.045  17.343  21.238  1.00 29.84  ? 417 GLU B OE2 1 
ATOM   6747  N  N   . GLN B 1 418 ? 19.618  19.969  16.871  1.00 27.68  ? 418 GLN B N   1 
ATOM   6748  C  CA  . GLN B 1 418 ? 20.667  20.951  16.642  1.00 27.92  ? 418 GLN B CA  1 
ATOM   6749  C  C   . GLN B 1 418 ? 20.208  22.354  17.029  1.00 27.58  ? 418 GLN B C   1 
ATOM   6750  O  O   . GLN B 1 418 ? 20.864  23.020  17.840  1.00 30.68  ? 418 GLN B O   1 
ATOM   6751  C  CB  . GLN B 1 418 ? 21.140  20.848  15.187  1.00 22.79  ? 418 GLN B CB  1 
ATOM   6752  C  CG  . GLN B 1 418 ? 22.017  19.612  14.981  1.00 28.59  ? 418 GLN B CG  1 
ATOM   6753  C  CD  . GLN B 1 418 ? 23.263  19.632  15.868  1.00 34.16  ? 418 GLN B CD  1 
ATOM   6754  O  OE1 . GLN B 1 418 ? 24.021  20.613  15.884  1.00 29.68  ? 418 GLN B OE1 1 
ATOM   6755  N  NE2 . GLN B 1 418 ? 23.468  18.558  16.625  1.00 29.78  ? 418 GLN B NE2 1 
ATOM   6756  N  N   . VAL B 1 419 ? 19.042  22.800  16.529  1.00 24.47  ? 419 VAL B N   1 
ATOM   6757  C  CA  . VAL B 1 419 ? 18.567  24.134  16.905  1.00 22.43  ? 419 VAL B CA  1 
ATOM   6758  C  C   . VAL B 1 419 ? 18.359  24.241  18.419  1.00 28.60  ? 419 VAL B C   1 
ATOM   6759  O  O   . VAL B 1 419 ? 18.724  25.250  19.029  1.00 24.80  ? 419 VAL B O   1 
ATOM   6760  C  CB  . VAL B 1 419 ? 17.296  24.509  16.129  1.00 17.76  ? 419 VAL B CB  1 
ATOM   6761  C  CG1 . VAL B 1 419 ? 16.755  25.798  16.617  1.00 27.52  ? 419 VAL B CG1 1 
ATOM   6762  C  CG2 . VAL B 1 419 ? 17.598  24.646  14.643  1.00 26.14  ? 419 VAL B CG2 1 
ATOM   6763  N  N   . ARG B 1 420 ? 17.794  23.198  19.061  1.00 25.76  ? 420 ARG B N   1 
ATOM   6764  C  CA  . ARG B 1 420 ? 17.567  23.277  20.507  1.00 23.35  ? 420 ARG B CA  1 
ATOM   6765  C  C   . ARG B 1 420 ? 18.877  23.458  21.263  1.00 23.35  ? 420 ARG B C   1 
ATOM   6766  O  O   . ARG B 1 420 ? 18.949  24.251  22.209  1.00 28.64  ? 420 ARG B O   1 
ATOM   6767  C  CB  . ARG B 1 420 ? 16.845  22.032  21.028  1.00 26.51  ? 420 ARG B CB  1 
ATOM   6768  C  CG  . ARG B 1 420 ? 15.464  21.796  20.431  1.00 28.93  ? 420 ARG B CG  1 
ATOM   6769  C  CD  . ARG B 1 420 ? 14.921  20.416  20.831  1.00 29.13  ? 420 ARG B CD  1 
ATOM   6770  N  NE  . ARG B 1 420 ? 14.468  20.424  22.208  1.00 22.77  ? 420 ARG B NE  1 
ATOM   6771  C  CZ  . ARG B 1 420 ? 13.333  20.978  22.620  1.00 28.33  ? 420 ARG B CZ  1 
ATOM   6772  N  NH1 . ARG B 1 420 ? 12.509  21.585  21.778  1.00 25.56  ? 420 ARG B NH1 1 
ATOM   6773  N  NH2 . ARG B 1 420 ? 13.023  20.938  23.912  1.00 21.65  ? 420 ARG B NH2 1 
ATOM   6774  N  N   . ARG B 1 421 ? 19.912  22.715  20.877  1.00 23.06  ? 421 ARG B N   1 
ATOM   6775  C  CA  . ARG B 1 421 ? 21.227  22.912  21.472  1.00 26.48  ? 421 ARG B CA  1 
ATOM   6776  C  C   . ARG B 1 421 ? 21.726  24.329  21.231  1.00 26.00  ? 421 ARG B C   1 
ATOM   6777  O  O   . ARG B 1 421 ? 22.314  24.949  22.126  1.00 27.83  ? 421 ARG B O   1 
ATOM   6778  C  CB  . ARG B 1 421 ? 22.222  21.903  20.906  1.00 24.88  ? 421 ARG B CB  1 
ATOM   6779  C  CG  . ARG B 1 421 ? 22.103  20.515  21.498  1.00 25.43  ? 421 ARG B CG  1 
ATOM   6780  C  CD  . ARG B 1 421 ? 22.755  19.456  20.587  1.00 29.97  ? 421 ARG B CD  1 
ATOM   6781  N  NE  . ARG B 1 421 ? 22.220  18.118  20.818  1.00 28.65  ? 421 ARG B NE  1 
ATOM   6782  C  CZ  . ARG B 1 421 ? 22.769  16.995  20.378  1.00 31.50  ? 421 ARG B CZ  1 
ATOM   6783  N  NH1 . ARG B 1 421 ? 23.909  17.000  19.694  1.00 28.17  ? 421 ARG B NH1 1 
ATOM   6784  N  NH2 . ARG B 1 421 ? 22.158  15.834  20.628  1.00 30.37  ? 421 ARG B NH2 1 
ATOM   6785  N  N   . GLN B 1 422 ? 21.465  24.878  20.047  1.00 25.90  ? 422 GLN B N   1 
ATOM   6786  C  CA  . GLN B 1 422 ? 21.932  26.233  19.770  1.00 28.36  ? 422 GLN B CA  1 
ATOM   6787  C  C   . GLN B 1 422 ? 21.332  27.239  20.750  1.00 27.69  ? 422 GLN B C   1 
ATOM   6788  O  O   . GLN B 1 422 ? 22.060  28.016  21.375  1.00 29.52  ? 422 GLN B O   1 
ATOM   6789  C  CB  . GLN B 1 422 ? 21.630  26.638  18.328  1.00 24.46  ? 422 GLN B CB  1 
ATOM   6790  C  CG  . GLN B 1 422 ? 22.583  27.743  17.913  1.00 30.69  ? 422 GLN B CG  1 
ATOM   6791  C  CD  . GLN B 1 422 ? 22.082  28.658  16.806  1.00 31.65  ? 422 GLN B CD  1 
ATOM   6792  O  OE1 . GLN B 1 422 ? 20.885  28.714  16.500  1.00 28.61  ? 422 GLN B OE1 1 
ATOM   6793  N  NE2 . GLN B 1 422 ? 23.019  29.389  16.193  1.00 26.65  ? 422 GLN B NE2 1 
ATOM   6794  N  N   . HIS B 1 423 ? 20.002  27.226  20.909  1.00 29.68  ? 423 HIS B N   1 
ATOM   6795  C  CA  . HIS B 1 423 ? 19.351  28.140  21.844  1.00 28.37  ? 423 HIS B CA  1 
ATOM   6796  C  C   . HIS B 1 423 ? 19.754  27.866  23.290  1.00 28.79  ? 423 HIS B C   1 
ATOM   6797  O  O   . HIS B 1 423 ? 19.849  28.798  24.099  1.00 31.45  ? 423 HIS B O   1 
ATOM   6798  C  CB  . HIS B 1 423 ? 17.833  28.047  21.686  1.00 27.11  ? 423 HIS B CB  1 
ATOM   6799  C  CG  . HIS B 1 423 ? 17.320  28.721  20.450  1.00 22.91  ? 423 HIS B CG  1 
ATOM   6800  N  ND1 . HIS B 1 423 ? 16.522  29.840  20.492  1.00 23.55  ? 423 HIS B ND1 1 
ATOM   6801  C  CD2 . HIS B 1 423 ? 17.505  28.440  19.139  1.00 22.44  ? 423 HIS B CD2 1 
ATOM   6802  C  CE1 . HIS B 1 423 ? 16.230  30.220  19.262  1.00 23.05  ? 423 HIS B CE1 1 
ATOM   6803  N  NE2 . HIS B 1 423 ? 16.820  29.392  18.420  1.00 22.60  ? 423 HIS B NE2 1 
ATOM   6804  N  N   . SER B 1 424 ? 19.992  26.610  23.641  1.00 26.41  ? 424 SER B N   1 
ATOM   6805  C  CA  . SER B 1 424 ? 20.415  26.323  25.006  1.00 27.60  ? 424 SER B CA  1 
ATOM   6806  C  C   . SER B 1 424 ? 21.824  26.857  25.278  1.00 29.84  ? 424 SER B C   1 
ATOM   6807  O  O   . SER B 1 424 ? 22.071  27.487  26.312  1.00 27.35  ? 424 SER B O   1 
ATOM   6808  C  CB  . SER B 1 424 ? 20.348  24.830  25.263  1.00 22.72  ? 424 SER B CB  1 
ATOM   6809  O  OG  . SER B 1 424 ? 20.750  24.579  26.591  1.00 28.54  ? 424 SER B OG  1 
ATOM   6810  N  N   . LEU B 1 425 ? 22.759  26.615  24.356  1.00 30.53  ? 425 LEU B N   1 
ATOM   6811  C  CA  . LEU B 1 425 ? 24.126  27.110  24.503  1.00 26.19  ? 425 LEU B CA  1 
ATOM   6812  C  C   . LEU B 1 425 ? 24.159  28.627  24.637  1.00 33.05  ? 425 LEU B C   1 
ATOM   6813  O  O   . LEU B 1 425 ? 24.773  29.165  25.563  1.00 30.09  ? 425 LEU B O   1 
ATOM   6814  C  CB  . LEU B 1 425 ? 24.959  26.680  23.301  1.00 33.80  ? 425 LEU B CB  1 
ATOM   6815  C  CG  . LEU B 1 425 ? 26.420  27.145  23.273  1.00 31.49  ? 425 LEU B CG  1 
ATOM   6816  C  CD1 . LEU B 1 425 ? 27.123  26.813  24.589  1.00 28.72  ? 425 LEU B CD1 1 
ATOM   6817  C  CD2 . LEU B 1 425 ? 27.156  26.521  22.070  1.00 33.55  ? 425 LEU B CD2 1 
ATOM   6818  N  N   . ILE B 1 426 ? 23.487  29.329  23.719  1.00 32.41  ? 426 ILE B N   1 
ATOM   6819  C  CA  . ILE B 1 426 ? 23.599  30.782  23.634  1.00 31.09  ? 426 ILE B CA  1 
ATOM   6820  C  C   . ILE B 1 426 ? 22.938  31.447  24.826  1.00 34.64  ? 426 ILE B C   1 
ATOM   6821  O  O   . ILE B 1 426 ? 23.470  32.417  25.384  1.00 29.71  ? 426 ILE B O   1 
ATOM   6822  C  CB  . ILE B 1 426 ? 22.984  31.288  22.317  1.00 28.79  ? 426 ILE B CB  1 
ATOM   6823  C  CG1 . ILE B 1 426 ? 23.871  30.940  21.123  1.00 28.30  ? 426 ILE B CG1 1 
ATOM   6824  C  CG2 . ILE B 1 426 ? 22.766  32.776  22.373  1.00 28.55  ? 426 ILE B CG2 1 
ATOM   6825  C  CD1 . ILE B 1 426 ? 23.253  31.339  19.788  1.00 26.60  ? 426 ILE B CD1 1 
ATOM   6826  N  N   . ARG B 1 427 ? 21.735  30.987  25.187  1.00 27.40  ? 427 ARG B N   1 
ATOM   6827  C  CA  . ARG B 1 427 ? 21.048  31.542  26.342  1.00 28.79  ? 427 ARG B CA  1 
ATOM   6828  C  C   . ARG B 1 427 ? 21.877  31.321  27.605  1.00 30.04  ? 427 ARG B C   1 
ATOM   6829  O  O   . ARG B 1 427 ? 21.931  32.186  28.485  1.00 31.40  ? 427 ARG B O   1 
ATOM   6830  C  CB  . ARG B 1 427 ? 19.649  30.907  26.482  1.00 31.46  ? 427 ARG B CB  1 
ATOM   6831  C  CG  . ARG B 1 427 ? 18.523  31.590  25.682  1.00 27.06  ? 427 ARG B CG  1 
ATOM   6832  C  CD  . ARG B 1 427 ? 17.231  30.743  25.657  1.00 30.72  ? 427 ARG B CD  1 
ATOM   6833  N  NE  . ARG B 1 427 ? 16.026  31.549  25.464  1.00 34.13  ? 427 ARG B NE  1 
ATOM   6834  C  CZ  . ARG B 1 427 ? 15.118  31.393  24.501  1.00 37.59  ? 427 ARG B CZ  1 
ATOM   6835  N  NH1 . ARG B 1 427 ? 15.195  30.407  23.597  1.00 33.65  ? 427 ARG B NH1 1 
ATOM   6836  N  NH2 . ARG B 1 427 ? 14.104  32.255  24.430  1.00 41.16  ? 427 ARG B NH2 1 
ATOM   6837  N  N   . GLN B 1 428 ? 22.550  30.175  27.702  1.00 31.56  ? 428 GLN B N   1 
ATOM   6838  C  CA  . GLN B 1 428 ? 23.390  29.914  28.868  1.00 33.03  ? 428 GLN B CA  1 
ATOM   6839  C  C   . GLN B 1 428 ? 24.636  30.798  28.869  1.00 36.49  ? 428 GLN B C   1 
ATOM   6840  O  O   . GLN B 1 428 ? 24.980  31.390  29.898  1.00 32.29  ? 428 GLN B O   1 
ATOM   6841  C  CB  . GLN B 1 428 ? 23.790  28.452  28.916  1.00 26.09  ? 428 GLN B CB  1 
ATOM   6842  C  CG  . GLN B 1 428 ? 22.702  27.502  29.404  1.00 31.78  ? 428 GLN B CG  1 
ATOM   6843  C  CD  . GLN B 1 428 ? 23.191  26.083  29.387  1.00 34.53  ? 428 GLN B CD  1 
ATOM   6844  O  OE1 . GLN B 1 428 ? 22.727  25.264  28.594  1.00 35.83  ? 428 GLN B OE1 1 
ATOM   6845  N  NE2 . GLN B 1 428 ? 24.163  25.779  30.250  1.00 36.69  ? 428 GLN B NE2 1 
ATOM   6846  N  N   . ILE B 1 429 ? 25.354  30.859  27.741  1.00 31.31  ? 429 ILE B N   1 
ATOM   6847  C  CA  . ILE B 1 429 ? 26.482  31.791  27.628  1.00 34.19  ? 429 ILE B CA  1 
ATOM   6848  C  C   . ILE B 1 429 ? 26.031  33.193  27.998  1.00 36.35  ? 429 ILE B C   1 
ATOM   6849  O  O   . ILE B 1 429 ? 26.615  33.845  28.871  1.00 42.01  ? 429 ILE B O   1 
ATOM   6850  C  CB  . ILE B 1 429 ? 27.084  31.774  26.211  1.00 32.87  ? 429 ILE B CB  1 
ATOM   6851  C  CG1 . ILE B 1 429 ? 27.908  30.510  25.979  1.00 38.36  ? 429 ILE B CG1 1 
ATOM   6852  C  CG2 . ILE B 1 429 ? 27.964  33.001  26.005  1.00 39.03  ? 429 ILE B CG2 1 
ATOM   6853  C  CD1 . ILE B 1 429 ? 28.278  30.271  24.519  1.00 33.32  ? 429 ILE B CD1 1 
ATOM   6854  N  N   . ALA B 1 430 ? 24.985  33.678  27.320  1.00 34.52  ? 430 ALA B N   1 
ATOM   6855  C  CA  . ALA B 1 430 ? 24.465  35.018  27.587  1.00 36.56  ? 430 ALA B CA  1 
ATOM   6856  C  C   . ALA B 1 430 ? 24.273  35.260  29.075  1.00 39.02  ? 430 ALA B C   1 
ATOM   6857  O  O   . ALA B 1 430 ? 24.601  36.334  29.586  1.00 34.93  ? 430 ALA B O   1 
ATOM   6858  C  CB  . ALA B 1 430 ? 23.139  35.226  26.852  1.00 34.20  ? 430 ALA B CB  1 
ATOM   6859  N  N   . ASP B 1 431 ? 23.752  34.257  29.792  1.00 44.87  ? 431 ASP B N   1 
ATOM   6860  C  CA  . ASP B 1 431 ? 23.503  34.404  31.223  1.00 39.36  ? 431 ASP B CA  1 
ATOM   6861  C  C   . ASP B 1 431 ? 24.805  34.548  32.006  1.00 40.61  ? 431 ASP B C   1 
ATOM   6862  O  O   . ASP B 1 431 ? 24.840  35.261  33.016  1.00 42.35  ? 431 ASP B O   1 
ATOM   6863  C  CB  . ASP B 1 431 ? 22.693  33.208  31.742  1.00 33.82  ? 431 ASP B CB  1 
ATOM   6864  C  CG  . ASP B 1 431 ? 21.185  33.414  31.614  1.00 37.30  ? 431 ASP B CG  1 
ATOM   6865  O  OD1 . ASP B 1 431 ? 20.747  34.229  30.773  1.00 35.40  ? 431 ASP B OD1 1 
ATOM   6866  O  OD2 . ASP B 1 431 ? 20.428  32.744  32.350  1.00 41.06  ? 431 ASP B OD2 1 
ATOM   6867  N  N   . ARG B 1 432 ? 25.874  33.875  31.566  1.00 42.85  ? 432 ARG B N   1 
ATOM   6868  C  CA  . ARG B 1 432 ? 27.169  34.007  32.234  1.00 48.10  ? 432 ARG B CA  1 
ATOM   6869  C  C   . ARG B 1 432 ? 27.772  35.390  32.031  1.00 46.05  ? 432 ARG B C   1 
ATOM   6870  O  O   . ARG B 1 432 ? 28.408  35.933  32.942  1.00 47.87  ? 432 ARG B O   1 
ATOM   6871  C  CB  . ARG B 1 432 ? 28.143  32.954  31.724  1.00 47.82  ? 432 ARG B CB  1 
ATOM   6872  C  CG  . ARG B 1 432 ? 29.399  32.916  32.536  1.00 45.12  ? 432 ARG B CG  1 
ATOM   6873  C  CD  . ARG B 1 432 ? 30.307  31.826  32.073  1.00 49.59  ? 432 ARG B CD  1 
ATOM   6874  N  NE  . ARG B 1 432 ? 30.339  31.669  30.628  1.00 45.78  ? 432 ARG B NE  1 
ATOM   6875  C  CZ  . ARG B 1 432 ? 31.038  30.727  30.015  1.00 47.66  ? 432 ARG B CZ  1 
ATOM   6876  N  NH1 . ARG B 1 432 ? 31.715  29.817  30.698  1.00 52.31  ? 432 ARG B NH1 1 
ATOM   6877  N  NH2 . ARG B 1 432 ? 31.064  30.699  28.688  1.00 49.96  ? 432 ARG B NH2 1 
ATOM   6878  N  N   . LEU B 1 433 ? 27.605  35.962  30.839  1.00 43.70  ? 433 LEU B N   1 
ATOM   6879  C  CA  . LEU B 1 433 ? 28.056  37.326  30.587  1.00 40.24  ? 433 LEU B CA  1 
ATOM   6880  C  C   . LEU B 1 433 ? 27.321  38.323  31.465  1.00 44.86  ? 433 LEU B C   1 
ATOM   6881  O  O   . LEU B 1 433 ? 27.854  39.402  31.749  1.00 42.01  ? 433 LEU B O   1 
ATOM   6882  C  CB  . LEU B 1 433 ? 27.861  37.671  29.106  1.00 38.62  ? 433 LEU B CB  1 
ATOM   6883  C  CG  . LEU B 1 433 ? 28.517  36.736  28.073  1.00 43.17  ? 433 LEU B CG  1 
ATOM   6884  C  CD1 . LEU B 1 433 ? 28.269  37.232  26.669  1.00 40.84  ? 433 LEU B CD1 1 
ATOM   6885  C  CD2 . LEU B 1 433 ? 30.016  36.578  28.290  1.00 46.09  ? 433 LEU B CD2 1 
ATOM   6886  N  N   . ALA B 1 434 ? 26.111  37.980  31.912  1.00 46.19  ? 434 ALA B N   1 
ATOM   6887  C  CA  . ALA B 1 434 ? 25.387  38.812  32.862  1.00 47.00  ? 434 ALA B CA  1 
ATOM   6888  C  C   . ALA B 1 434 ? 26.051  38.840  34.226  1.00 43.86  ? 434 ALA B C   1 
ATOM   6889  O  O   . ALA B 1 434 ? 25.691  39.683  35.054  1.00 50.29  ? 434 ALA B O   1 
ATOM   6890  C  CB  . ALA B 1 434 ? 23.947  38.325  32.994  1.00 49.79  ? 434 ALA B CB  1 
ATOM   6891  N  N   . GLU B 1 435 ? 27.012  37.958  34.463  1.00 47.32  ? 435 GLU B N   1 
ATOM   6892  C  CA  . GLU B 1 435 ? 27.832  37.961  35.664  1.00 52.10  ? 435 GLU B CA  1 
ATOM   6893  C  C   . GLU B 1 435 ? 29.200  38.565  35.321  1.00 55.41  ? 435 GLU B C   1 
ATOM   6894  O  O   . GLU B 1 435 ? 29.942  39.014  36.195  1.00 55.05  ? 435 GLU B O   1 
ATOM   6895  C  CB  . GLU B 1 435 ? 27.970  36.531  36.190  1.00 52.77  ? 435 GLU B CB  1 
ATOM   6896  C  CG  . GLU B 1 435 ? 26.802  35.655  35.749  1.00 52.87  ? 435 GLU B CG  1 
ATOM   6897  C  CD  . GLU B 1 435 ? 26.656  34.355  36.532  1.00 64.43  ? 435 GLU B CD  1 
ATOM   6898  O  OE1 . GLU B 1 435 ? 27.615  33.546  36.552  1.00 63.54  ? 435 GLU B OE1 1 
ATOM   6899  O  OE2 . GLU B 1 435 ? 25.568  34.137  37.115  1.00 65.23  ? 435 GLU B OE2 1 
ATOM   6900  N  N   . MET C 1 1   ? -8.514  26.024  -41.865 1.00 40.16  ? 1   MET C N   1 
ATOM   6901  C  CA  . MET C 1 1   ? -9.142  27.339  -41.908 1.00 40.00  ? 1   MET C CA  1 
ATOM   6902  C  C   . MET C 1 1   ? -10.672 27.288  -41.991 1.00 36.53  ? 1   MET C C   1 
ATOM   6903  O  O   . MET C 1 1   ? -11.253 26.713  -42.908 1.00 39.00  ? 1   MET C O   1 
ATOM   6904  C  CB  . MET C 1 1   ? -8.599  28.158  -43.090 1.00 37.26  ? 1   MET C CB  1 
ATOM   6905  C  CG  . MET C 1 1   ? -7.089  28.397  -43.071 1.00 35.92  ? 1   MET C CG  1 
ATOM   6906  S  SD  . MET C 1 1   ? -6.625  29.805  -44.118 1.00 46.80  ? 1   MET C SD  1 
ATOM   6907  C  CE  . MET C 1 1   ? -8.139  30.090  -45.019 1.00 38.14  ? 1   MET C CE  1 
ATOM   6908  N  N   . LEU C 1 2   ? -11.295 27.959  -41.030 1.00 33.24  ? 2   LEU C N   1 
ATOM   6909  C  CA  . LEU C 1 2   ? -12.741 28.090  -40.983 1.00 28.88  ? 2   LEU C CA  1 
ATOM   6910  C  C   . LEU C 1 2   ? -13.274 28.763  -42.242 1.00 28.60  ? 2   LEU C C   1 
ATOM   6911  O  O   . LEU C 1 2   ? -12.574 29.503  -42.927 1.00 23.62  ? 2   LEU C O   1 
ATOM   6912  C  CB  . LEU C 1 2   ? -13.129 28.897  -39.739 1.00 28.79  ? 2   LEU C CB  1 
ATOM   6913  C  CG  . LEU C 1 2   ? -12.699 28.159  -38.461 1.00 28.93  ? 2   LEU C CG  1 
ATOM   6914  C  CD1 . LEU C 1 2   ? -12.877 28.985  -37.181 1.00 26.98  ? 2   LEU C CD1 1 
ATOM   6915  C  CD2 . LEU C 1 2   ? -13.482 26.855  -38.374 1.00 24.89  ? 2   LEU C CD2 1 
ATOM   6916  N  N   . LEU C 1 3   ? -14.530 28.504  -42.549 1.00 31.05  ? 3   LEU C N   1 
ATOM   6917  C  CA  . LEU C 1 3   ? -15.182 29.168  -43.663 1.00 25.17  ? 3   LEU C CA  1 
ATOM   6918  C  C   . LEU C 1 3   ? -16.177 30.186  -43.123 1.00 31.74  ? 3   LEU C C   1 
ATOM   6919  O  O   . LEU C 1 3   ? -16.573 30.138  -41.956 1.00 29.45  ? 3   LEU C O   1 
ATOM   6920  C  CB  . LEU C 1 3   ? -15.867 28.143  -44.569 1.00 23.03  ? 3   LEU C CB  1 
ATOM   6921  C  CG  . LEU C 1 3   ? -14.834 27.300  -45.317 1.00 24.41  ? 3   LEU C CG  1 
ATOM   6922  C  CD1 . LEU C 1 3   ? -15.436 26.050  -45.907 1.00 26.48  ? 3   LEU C CD1 1 
ATOM   6923  C  CD2 . LEU C 1 3   ? -14.154 28.163  -46.439 1.00 27.40  ? 3   LEU C CD2 1 
ATOM   6924  N  N   . GLU C 1 4   ? -16.529 31.156  -43.963 1.00 28.50  ? 4   GLU C N   1 
ATOM   6925  C  CA  . GLU C 1 4   ? -17.596 32.087  -43.627 1.00 30.06  ? 4   GLU C CA  1 
ATOM   6926  C  C   . GLU C 1 4   ? -18.950 31.403  -43.841 1.00 32.71  ? 4   GLU C C   1 
ATOM   6927  O  O   . GLU C 1 4   ? -19.080 30.479  -44.649 1.00 32.85  ? 4   GLU C O   1 
ATOM   6928  C  CB  . GLU C 1 4   ? -17.443 33.374  -44.455 1.00 30.31  ? 4   GLU C CB  1 
ATOM   6929  C  CG  . GLU C 1 4   ? -15.969 33.913  -44.410 1.00 26.89  ? 4   GLU C CG  1 
ATOM   6930  C  CD  . GLU C 1 4   ? -15.527 34.730  -45.630 1.00 34.22  ? 4   GLU C CD  1 
ATOM   6931  O  OE1 . GLU C 1 4   ? -16.345 35.488  -46.187 1.00 30.22  ? 4   GLU C OE1 1 
ATOM   6932  O  OE2 . GLU C 1 4   ? -14.348 34.604  -46.044 1.00 37.01  ? 4   GLU C OE2 1 
ATOM   6933  N  N   . ARG C 1 5   ? -19.957 31.833  -43.069 1.00 34.04  ? 5   ARG C N   1 
ATOM   6934  C  CA  . ARG C 1 5   ? -21.271 31.184  -43.124 1.00 31.35  ? 5   ARG C CA  1 
ATOM   6935  C  C   . ARG C 1 5   ? -21.960 31.390  -44.474 1.00 35.47  ? 5   ARG C C   1 
ATOM   6936  O  O   . ARG C 1 5   ? -22.579 30.459  -45.003 1.00 38.06  ? 5   ARG C O   1 
ATOM   6937  C  CB  . ARG C 1 5   ? -22.184 31.699  -42.008 1.00 35.24  ? 5   ARG C CB  1 
ATOM   6938  C  CG  . ARG C 1 5   ? -22.488 30.687  -40.870 1.00 33.78  ? 5   ARG C CG  1 
ATOM   6939  C  CD  . ARG C 1 5   ? -23.291 29.502  -41.318 1.00 31.38  ? 5   ARG C CD  1 
ATOM   6940  N  NE  . ARG C 1 5   ? -24.189 28.940  -40.312 1.00 33.00  ? 5   ARG C NE  1 
ATOM   6941  C  CZ  . ARG C 1 5   ? -23.841 28.317  -39.190 1.00 31.55  ? 5   ARG C CZ  1 
ATOM   6942  N  NH1 . ARG C 1 5   ? -22.588 28.286  -38.759 1.00 27.33  ? 5   ARG C NH1 1 
ATOM   6943  N  NH2 . ARG C 1 5   ? -24.781 27.691  -38.486 1.00 37.49  ? 5   ARG C NH2 1 
ATOM   6944  N  N   . ASP C 1 6   ? -21.931 32.610  -45.018 1.00 35.91  ? 6   ASP C N   1 
ATOM   6945  C  CA  . ASP C 1 6   ? -22.470 32.812  -46.360 1.00 37.38  ? 6   ASP C CA  1 
ATOM   6946  C  C   . ASP C 1 6   ? -21.783 31.850  -47.310 1.00 30.64  ? 6   ASP C C   1 
ATOM   6947  O  O   . ASP C 1 6   ? -20.559 31.688  -47.253 1.00 32.53  ? 6   ASP C O   1 
ATOM   6948  C  CB  . ASP C 1 6   ? -22.250 34.247  -46.841 1.00 35.29  ? 6   ASP C CB  1 
ATOM   6949  C  CG  . ASP C 1 6   ? -22.958 35.279  -45.987 1.00 40.51  ? 6   ASP C CG  1 
ATOM   6950  O  OD1 . ASP C 1 6   ? -24.000 34.955  -45.355 1.00 45.15  ? 6   ASP C OD1 1 
ATOM   6951  O  OD2 . ASP C 1 6   ? -22.444 36.415  -45.943 1.00 34.22  ? 6   ASP C OD2 1 
ATOM   6952  N  N   . LEU C 1 7   ? -22.573 31.175  -48.148 1.00 30.89  ? 7   LEU C N   1 
ATOM   6953  C  CA  . LEU C 1 7   ? -21.971 30.229  -49.084 1.00 28.79  ? 7   LEU C CA  1 
ATOM   6954  C  C   . LEU C 1 7   ? -20.899 30.917  -49.927 1.00 27.07  ? 7   LEU C C   1 
ATOM   6955  O  O   . LEU C 1 7   ? -19.791 30.395  -50.089 1.00 28.04  ? 7   LEU C O   1 
ATOM   6956  C  CB  . LEU C 1 7   ? -23.050 29.578  -49.952 1.00 25.99  ? 7   LEU C CB  1 
ATOM   6957  C  CG  . LEU C 1 7   ? -24.039 28.654  -49.233 1.00 35.78  ? 7   LEU C CG  1 
ATOM   6958  C  CD1 . LEU C 1 7   ? -25.022 28.033  -50.202 1.00 27.14  ? 7   LEU C CD1 1 
ATOM   6959  C  CD2 . LEU C 1 7   ? -23.336 27.565  -48.422 1.00 30.21  ? 7   LEU C CD2 1 
ATOM   6960  N  N   . ILE C 1 8   ? -21.170 32.135  -50.381 1.00 25.79  ? 8   ILE C N   1 
ATOM   6961  C  CA  . ILE C 1 8   ? -20.207 32.921  -51.146 1.00 22.75  ? 8   ILE C CA  1 
ATOM   6962  C  C   . ILE C 1 8   ? -19.216 33.557  -50.182 1.00 29.92  ? 8   ILE C C   1 
ATOM   6963  O  O   . ILE C 1 8   ? -19.598 34.368  -49.330 1.00 31.42  ? 8   ILE C O   1 
ATOM   6964  C  CB  . ILE C 1 8   ? -20.923 33.994  -51.981 1.00 26.32  ? 8   ILE C CB  1 
ATOM   6965  C  CG1 . ILE C 1 8   ? -21.912 33.322  -52.969 1.00 26.82  ? 8   ILE C CG1 1 
ATOM   6966  C  CG2 . ILE C 1 8   ? -19.909 34.873  -52.695 1.00 27.90  ? 8   ILE C CG2 1 
ATOM   6967  C  CD1 . ILE C 1 8   ? -22.906 34.272  -53.646 1.00 32.32  ? 8   ILE C CD1 1 
ATOM   6968  N  N   . GLN C 1 9   ? -17.944 33.196  -50.308 1.00 29.00  ? 9   GLN C N   1 
ATOM   6969  C  CA  . GLN C 1 9   ? -16.925 33.769  -49.438 1.00 29.36  ? 9   GLN C CA  1 
ATOM   6970  C  C   . GLN C 1 9   ? -16.559 35.171  -49.911 1.00 33.91  ? 9   GLN C C   1 
ATOM   6971  O  O   . GLN C 1 9   ? -16.480 35.420  -51.116 1.00 32.68  ? 9   GLN C O   1 
ATOM   6972  C  CB  . GLN C 1 9   ? -15.679 32.892  -49.435 1.00 24.76  ? 9   GLN C CB  1 
ATOM   6973  C  CG  . GLN C 1 9   ? -15.980 31.456  -49.173 1.00 22.06  ? 9   GLN C CG  1 
ATOM   6974  C  CD  . GLN C 1 9   ? -16.343 31.236  -47.721 1.00 30.15  ? 9   GLN C CD  1 
ATOM   6975  O  OE1 . GLN C 1 9   ? -15.504 31.387  -46.823 1.00 24.38  ? 9   GLN C OE1 1 
ATOM   6976  N  NE2 . GLN C 1 9   ? -17.611 30.912  -47.481 1.00 26.77  ? 9   GLN C NE2 1 
ATOM   6977  N  N   . SER C 1 10  ? -16.331 36.087  -48.958 1.00 29.51  ? 10  SER C N   1 
ATOM   6978  C  CA  . SER C 1 10  ? -15.677 37.350  -49.299 1.00 33.33  ? 10  SER C CA  1 
ATOM   6979  C  C   . SER C 1 10  ? -14.218 37.132  -49.675 1.00 32.96  ? 10  SER C C   1 
ATOM   6980  O  O   . SER C 1 10  ? -13.773 37.572  -50.741 1.00 27.41  ? 10  SER C O   1 
ATOM   6981  C  CB  . SER C 1 10  ? -15.768 38.351  -48.144 1.00 30.61  ? 10  SER C CB  1 
ATOM   6982  O  OG  . SER C 1 10  ? -17.066 38.894  -48.053 1.00 32.21  ? 10  SER C OG  1 
ATOM   6983  N  N   . VAL C 1 11  ? -13.451 36.466  -48.808 1.00 27.05  ? 11  VAL C N   1 
ATOM   6984  C  CA  . VAL C 1 11  ? -12.051 36.224  -49.130 1.00 28.59  ? 11  VAL C CA  1 
ATOM   6985  C  C   . VAL C 1 11  ? -11.958 35.404  -50.416 1.00 28.08  ? 11  VAL C C   1 
ATOM   6986  O  O   . VAL C 1 11  ? -12.729 34.460  -50.621 1.00 25.24  ? 11  VAL C O   1 
ATOM   6987  C  CB  . VAL C 1 11  ? -11.355 35.517  -47.957 1.00 29.70  ? 11  VAL C CB  1 
ATOM   6988  C  CG1 . VAL C 1 11  ? -9.910  35.200  -48.310 1.00 23.68  ? 11  VAL C CG1 1 
ATOM   6989  C  CG2 . VAL C 1 11  ? -11.473 36.358  -46.676 1.00 27.40  ? 11  VAL C CG2 1 
ATOM   6990  N  N   . GLY C 1 12  ? -11.029 35.789  -51.309 1.00 24.90  ? 12  GLY C N   1 
ATOM   6991  C  CA  . GLY C 1 12  ? -10.825 35.108  -52.579 1.00 25.78  ? 12  GLY C CA  1 
ATOM   6992  C  C   . GLY C 1 12  ? -11.551 35.688  -53.785 1.00 28.47  ? 12  GLY C C   1 
ATOM   6993  O  O   . GLY C 1 12  ? -11.389 35.160  -54.900 1.00 25.08  ? 12  GLY C O   1 
ATOM   6994  N  N   . PHE C 1 13  ? -12.369 36.725  -53.598 1.00 27.58  ? 13  PHE C N   1 
ATOM   6995  C  CA  . PHE C 1 13  ? -13.064 37.398  -54.691 1.00 26.02  ? 13  PHE C CA  1 
ATOM   6996  C  C   . PHE C 1 13  ? -12.126 38.429  -55.304 1.00 28.02  ? 13  PHE C C   1 
ATOM   6997  O  O   . PHE C 1 13  ? -11.878 39.488  -54.714 1.00 28.53  ? 13  PHE C O   1 
ATOM   6998  C  CB  . PHE C 1 13  ? -14.331 38.069  -54.186 1.00 25.19  ? 13  PHE C CB  1 
ATOM   6999  C  CG  . PHE C 1 13  ? -15.150 38.711  -55.266 1.00 27.48  ? 13  PHE C CG  1 
ATOM   7000  C  CD1 . PHE C 1 13  ? -15.329 38.073  -56.484 1.00 26.39  ? 13  PHE C CD1 1 
ATOM   7001  C  CD2 . PHE C 1 13  ? -15.773 39.939  -55.050 1.00 27.13  ? 13  PHE C CD2 1 
ATOM   7002  C  CE1 . PHE C 1 13  ? -16.122 38.663  -57.488 1.00 30.82  ? 13  PHE C CE1 1 
ATOM   7003  C  CE2 . PHE C 1 13  ? -16.551 40.533  -56.037 1.00 29.26  ? 13  PHE C CE2 1 
ATOM   7004  C  CZ  . PHE C 1 13  ? -16.732 39.898  -57.251 1.00 29.01  ? 13  PHE C CZ  1 
ATOM   7005  N  N   . ARG C 1 14  ? -11.608 38.133  -56.493 1.00 28.78  ? 14  ARG C N   1 
ATOM   7006  C  CA  . ARG C 1 14  ? -10.487 38.895  -57.026 1.00 24.17  ? 14  ARG C CA  1 
ATOM   7007  C  C   . ARG C 1 14  ? -10.409 38.674  -58.530 1.00 26.21  ? 14  ARG C C   1 
ATOM   7008  O  O   . ARG C 1 14  ? -10.894 37.671  -59.055 1.00 28.02  ? 14  ARG C O   1 
ATOM   7009  C  CB  . ARG C 1 14  ? -9.162  38.473  -56.374 1.00 25.47  ? 14  ARG C CB  1 
ATOM   7010  C  CG  . ARG C 1 14  ? -8.852  36.965  -56.526 1.00 28.77  ? 14  ARG C CG  1 
ATOM   7011  C  CD  . ARG C 1 14  ? -7.537  36.633  -55.842 1.00 29.08  ? 14  ARG C CD  1 
ATOM   7012  N  NE  . ARG C 1 14  ? -6.498  37.582  -56.234 1.00 32.41  ? 14  ARG C NE  1 
ATOM   7013  C  CZ  . ARG C 1 14  ? -5.601  38.090  -55.401 1.00 36.41  ? 14  ARG C CZ  1 
ATOM   7014  N  NH1 . ARG C 1 14  ? -5.614  37.797  -54.113 1.00 42.55  ? 14  ARG C NH1 1 
ATOM   7015  N  NH2 . ARG C 1 14  ? -4.690  38.939  -55.867 1.00 42.92  ? 14  ARG C NH2 1 
ATOM   7016  N  N   . ASN C 1 15  ? -9.753  39.601  -59.212 1.00 28.40  ? 15  ASN C N   1 
ATOM   7017  C  CA  . ASN C 1 15  ? -9.494  39.378  -60.622 1.00 30.19  ? 15  ASN C CA  1 
ATOM   7018  C  C   . ASN C 1 15  ? -8.314  38.426  -60.778 1.00 31.81  ? 15  ASN C C   1 
ATOM   7019  O  O   . ASN C 1 15  ? -7.435  38.335  -59.909 1.00 34.01  ? 15  ASN C O   1 
ATOM   7020  C  CB  . ASN C 1 15  ? -9.227  40.693  -61.339 1.00 25.96  ? 15  ASN C CB  1 
ATOM   7021  C  CG  . ASN C 1 15  ? -10.489 41.451  -61.638 1.00 27.24  ? 15  ASN C CG  1 
ATOM   7022  O  OD1 . ASN C 1 15  ? -11.524 40.869  -61.965 1.00 26.82  ? 15  ASN C OD1 1 
ATOM   7023  N  ND2 . ASN C 1 15  ? -10.427 42.756  -61.482 1.00 33.11  ? 15  ASN C ND2 1 
ATOM   7024  N  N   . VAL C 1 16  ? -8.315  37.697  -61.891 1.00 29.34  ? 16  VAL C N   1 
ATOM   7025  C  CA  . VAL C 1 16  ? -7.343  36.644  -62.160 1.00 31.55  ? 16  VAL C CA  1 
ATOM   7026  C  C   . VAL C 1 16  ? -6.490  37.063  -63.352 1.00 34.81  ? 16  VAL C C   1 
ATOM   7027  O  O   . VAL C 1 16  ? -7.011  37.536  -64.369 1.00 34.41  ? 16  VAL C O   1 
ATOM   7028  C  CB  . VAL C 1 16  ? -8.058  35.302  -62.392 1.00 33.20  ? 16  VAL C CB  1 
ATOM   7029  C  CG1 . VAL C 1 16  ? -7.122  34.255  -62.990 1.00 28.05  ? 16  VAL C CG1 1 
ATOM   7030  C  CG2 . VAL C 1 16  ? -8.644  34.814  -61.061 1.00 30.34  ? 16  VAL C CG2 1 
ATOM   7031  N  N   . ARG C 1 17  ? -5.180  36.913  -63.214 1.00 36.66  ? 17  ARG C N   1 
ATOM   7032  C  CA  A ARG C 1 17  ? -4.231  37.324  -64.235 0.61 37.54  ? 17  ARG C CA  1 
ATOM   7033  C  CA  B ARG C 1 17  ? -4.221  37.328  -64.226 0.39 37.54  ? 17  ARG C CA  1 
ATOM   7034  C  C   . ARG C 1 17  ? -3.373  36.138  -64.655 1.00 41.97  ? 17  ARG C C   1 
ATOM   7035  O  O   . ARG C 1 17  ? -3.093  35.235  -63.860 1.00 32.03  ? 17  ARG C O   1 
ATOM   7036  C  CB  A ARG C 1 17  ? -3.337  38.469  -63.728 0.61 39.44  ? 17  ARG C CB  1 
ATOM   7037  C  CB  B ARG C 1 17  ? -3.301  38.438  -63.699 0.39 39.43  ? 17  ARG C CB  1 
ATOM   7038  C  CG  A ARG C 1 17  ? -4.058  39.820  -63.630 0.61 40.41  ? 17  ARG C CG  1 
ATOM   7039  C  CG  B ARG C 1 17  ? -3.871  39.854  -63.768 0.39 40.34  ? 17  ARG C CG  1 
ATOM   7040  C  CD  A ARG C 1 17  ? -3.367  40.794  -62.681 0.61 41.30  ? 17  ARG C CD  1 
ATOM   7041  C  CD  B ARG C 1 17  ? -2.980  40.813  -62.979 0.39 40.80  ? 17  ARG C CD  1 
ATOM   7042  N  NE  A ARG C 1 17  ? -3.975  42.120  -62.751 0.61 41.35  ? 17  ARG C NE  1 
ATOM   7043  N  NE  B ARG C 1 17  ? -3.707  41.798  -62.181 0.39 40.89  ? 17  ARG C NE  1 
ATOM   7044  C  CZ  A ARG C 1 17  ? -3.531  43.111  -63.511 0.61 38.60  ? 17  ARG C CZ  1 
ATOM   7045  C  CZ  B ARG C 1 17  ? -4.579  41.516  -61.221 0.39 36.27  ? 17  ARG C CZ  1 
ATOM   7046  N  NH1 A ARG C 1 17  ? -2.432  42.989  -64.234 0.61 40.30  ? 17  ARG C NH1 1 
ATOM   7047  N  NH1 B ARG C 1 17  ? -4.916  40.271  -60.928 0.39 37.30  ? 17  ARG C NH1 1 
ATOM   7048  N  NH2 A ARG C 1 17  ? -4.210  44.253  -63.548 0.61 39.48  ? 17  ARG C NH2 1 
ATOM   7049  N  NH2 B ARG C 1 17  ? -5.122  42.510  -60.530 0.39 34.41  ? 17  ARG C NH2 1 
ATOM   7050  N  N   . GLU C 1 18  ? -2.980  36.140  -65.926 1.00 35.87  ? 18  GLU C N   1 
ATOM   7051  C  CA  . GLU C 1 18  ? -1.988  35.209  -66.466 1.00 33.13  ? 18  GLU C CA  1 
ATOM   7052  C  C   . GLU C 1 18  ? -1.114  36.059  -67.379 1.00 40.49  ? 18  GLU C C   1 
ATOM   7053  O  O   . GLU C 1 18  ? -1.548  36.436  -68.469 1.00 46.66  ? 18  GLU C O   1 
ATOM   7054  C  CB  . GLU C 1 18  ? -2.625  34.057  -67.232 1.00 39.40  ? 18  GLU C CB  1 
ATOM   7055  C  CG  . GLU C 1 18  ? -3.822  33.429  -66.536 1.00 42.57  ? 18  GLU C CG  1 
ATOM   7056  C  CD  . GLU C 1 18  ? -4.151  32.048  -67.059 1.00 49.17  ? 18  GLU C CD  1 
ATOM   7057  O  OE1 . GLU C 1 18  ? -3.726  31.709  -68.191 1.00 43.59  ? 18  GLU C OE1 1 
ATOM   7058  O  OE2 . GLU C 1 18  ? -4.833  31.300  -66.325 1.00 54.07  ? 18  GLU C OE2 1 
ATOM   7059  N  N   . GLY C 1 19  ? 0.078   36.414  -66.913 1.00 36.39  ? 19  GLY C N   1 
ATOM   7060  C  CA  . GLY C 1 19  ? 0.991   37.182  -67.734 1.00 41.26  ? 19  GLY C CA  1 
ATOM   7061  C  C   . GLY C 1 19  ? 0.742   38.672  -67.753 1.00 47.01  ? 19  GLY C C   1 
ATOM   7062  O  O   . GLY C 1 19  ? 1.116   39.338  -68.721 1.00 44.17  ? 19  GLY C O   1 
ATOM   7063  N  N   . GLY C 1 20  ? 0.129   39.220  -66.703 1.00 50.38  ? 20  GLY C N   1 
ATOM   7064  C  CA  . GLY C 1 20  ? -0.180  40.624  -66.611 1.00 45.29  ? 20  GLY C CA  1 
ATOM   7065  C  C   . GLY C 1 20  ? -1.595  40.978  -67.030 1.00 45.78  ? 20  GLY C C   1 
ATOM   7066  O  O   . GLY C 1 20  ? -2.165  41.937  -66.498 1.00 52.30  ? 20  GLY C O   1 
ATOM   7067  N  N   . GLU C 1 21  ? -2.174  40.232  -67.964 1.00 42.49  ? 21  GLU C N   1 
ATOM   7068  C  CA  . GLU C 1 21  ? -3.503  40.547  -68.467 1.00 47.00  ? 21  GLU C CA  1 
ATOM   7069  C  C   . GLU C 1 21  ? -4.586  39.795  -67.695 1.00 45.75  ? 21  GLU C C   1 
ATOM   7070  O  O   . GLU C 1 21  ? -4.424  38.615  -67.369 1.00 43.37  ? 21  GLU C O   1 
ATOM   7071  C  CB  . GLU C 1 21  ? -3.582  40.225  -69.955 1.00 50.08  ? 21  GLU C CB  1 
ATOM   7072  C  CG  . GLU C 1 21  ? -3.031  41.356  -70.811 1.00 59.58  ? 21  GLU C CG  1 
ATOM   7073  C  CD  . GLU C 1 21  ? -3.765  42.673  -70.556 1.00 61.38  ? 21  GLU C CD  1 
ATOM   7074  O  OE1 . GLU C 1 21  ? -3.131  43.743  -70.679 1.00 58.55  ? 21  GLU C OE1 1 
ATOM   7075  O  OE2 . GLU C 1 21  ? -4.976  42.635  -70.221 1.00 53.06  ? 21  GLU C OE2 1 
ATOM   7076  N  N   . ILE C 1 22  ? -5.686  40.487  -67.392 1.00 42.16  ? 22  ILE C N   1 
ATOM   7077  C  CA  . ILE C 1 22  ? -6.749  39.896  -66.576 1.00 40.75  ? 22  ILE C CA  1 
ATOM   7078  C  C   . ILE C 1 22  ? -7.595  38.981  -67.448 1.00 32.93  ? 22  ILE C C   1 
ATOM   7079  O  O   . ILE C 1 22  ? -8.138  39.404  -68.470 1.00 29.81  ? 22  ILE C O   1 
ATOM   7080  C  CB  . ILE C 1 22  ? -7.623  40.964  -65.901 1.00 38.02  ? 22  ILE C CB  1 
ATOM   7081  C  CG1 . ILE C 1 22  ? -6.807  41.791  -64.911 1.00 31.72  ? 22  ILE C CG1 1 
ATOM   7082  C  CG2 . ILE C 1 22  ? -8.806  40.296  -65.184 1.00 30.15  ? 22  ILE C CG2 1 
ATOM   7083  C  CD1 . ILE C 1 22  ? -7.623  42.868  -64.204 1.00 33.77  ? 22  ILE C CD1 1 
ATOM   7084  N  N   . THR C 1 23  ? -7.725  37.728  -67.027 1.00 30.89  ? 23  THR C N   1 
ATOM   7085  C  CA  . THR C 1 23  ? -8.484  36.739  -67.783 1.00 33.60  ? 23  THR C CA  1 
ATOM   7086  C  C   . THR C 1 23  ? -9.920  36.620  -67.312 1.00 31.43  ? 23  THR C C   1 
ATOM   7087  O  O   . THR C 1 23  ? -10.815 36.345  -68.114 1.00 23.99  ? 23  THR C O   1 
ATOM   7088  C  CB  . THR C 1 23  ? -7.798  35.375  -67.666 1.00 31.90  ? 23  THR C CB  1 
ATOM   7089  O  OG1 . THR C 1 23  ? -7.874  34.938  -66.310 1.00 33.18  ? 23  THR C OG1 1 
ATOM   7090  C  CG2 . THR C 1 23  ? -6.328  35.509  -68.030 1.00 36.37  ? 23  THR C CG2 1 
ATOM   7091  N  N   . GLY C 1 24  ? -10.157 36.814  -66.026 1.00 31.05  ? 24  GLY C N   1 
ATOM   7092  C  CA  . GLY C 1 24  ? -11.496 36.695  -65.497 1.00 26.36  ? 24  GLY C CA  1 
ATOM   7093  C  C   . GLY C 1 24  ? -11.463 37.058  -64.039 1.00 24.34  ? 24  GLY C C   1 
ATOM   7094  O  O   . GLY C 1 24  ? -10.544 37.736  -63.574 1.00 26.76  ? 24  GLY C O   1 
ATOM   7095  N  N   . PHE C 1 25  ? -12.458 36.585  -63.310 1.00 25.67  ? 25  PHE C N   1 
ATOM   7096  C  CA  . PHE C 1 25  ? -12.465 36.770  -61.872 1.00 23.40  ? 25  PHE C CA  1 
ATOM   7097  C  C   . PHE C 1 25  ? -12.831 35.446  -61.220 1.00 24.38  ? 25  PHE C C   1 
ATOM   7098  O  O   . PHE C 1 25  ? -13.431 34.567  -61.840 1.00 25.52  ? 25  PHE C O   1 
ATOM   7099  C  CB  . PHE C 1 25  ? -13.440 37.869  -61.447 1.00 21.80  ? 25  PHE C CB  1 
ATOM   7100  C  CG  . PHE C 1 25  ? -14.888 37.491  -61.612 1.00 28.65  ? 25  PHE C CG  1 
ATOM   7101  C  CD1 . PHE C 1 25  ? -15.528 37.654  -62.828 1.00 27.30  ? 25  PHE C CD1 1 
ATOM   7102  C  CD2 . PHE C 1 25  ? -15.598 36.942  -60.556 1.00 23.91  ? 25  PHE C CD2 1 
ATOM   7103  C  CE1 . PHE C 1 25  ? -16.842 37.306  -62.993 1.00 23.61  ? 25  PHE C CE1 1 
ATOM   7104  C  CE2 . PHE C 1 25  ? -16.917 36.577  -60.715 1.00 26.40  ? 25  PHE C CE2 1 
ATOM   7105  C  CZ  . PHE C 1 25  ? -17.546 36.763  -61.939 1.00 34.58  ? 25  PHE C CZ  1 
ATOM   7106  N  N   . GLN C 1 26  ? -12.465 35.311  -59.961 1.00 25.21  ? 26  GLN C N   1 
ATOM   7107  C  CA  . GLN C 1 26  ? -12.800 34.116  -59.217 1.00 24.83  ? 26  GLN C CA  1 
ATOM   7108  C  C   . GLN C 1 26  ? -13.500 34.483  -57.914 1.00 26.28  ? 26  GLN C C   1 
ATOM   7109  O  O   . GLN C 1 26  ? -13.495 35.633  -57.458 1.00 26.63  ? 26  GLN C O   1 
ATOM   7110  C  CB  . GLN C 1 26  ? -11.558 33.277  -58.929 1.00 28.59  ? 26  GLN C CB  1 
ATOM   7111  C  CG  . GLN C 1 26  ? -10.521 34.017  -58.128 1.00 28.21  ? 26  GLN C CG  1 
ATOM   7112  C  CD  . GLN C 1 26  ? -9.575  33.069  -57.474 1.00 31.95  ? 26  GLN C CD  1 
ATOM   7113  O  OE1 . GLN C 1 26  ? -9.123  32.124  -58.112 1.00 34.14  ? 26  GLN C OE1 1 
ATOM   7114  N  NE2 . GLN C 1 26  ? -9.257  33.306  -56.199 1.00 26.07  ? 26  GLN C NE2 1 
ATOM   7115  N  N   . PHE C 1 27  ? -14.095 33.467  -57.305 1.00 28.50  ? 27  PHE C N   1 
ATOM   7116  C  CA  . PHE C 1 27  ? -14.664 33.619  -55.987 1.00 23.77  ? 27  PHE C CA  1 
ATOM   7117  C  C   . PHE C 1 27  ? -14.799 32.229  -55.398 1.00 27.44  ? 27  PHE C C   1 
ATOM   7118  O  O   . PHE C 1 27  ? -14.808 31.219  -56.117 1.00 26.52  ? 27  PHE C O   1 
ATOM   7119  C  CB  . PHE C 1 27  ? -16.009 34.344  -56.030 1.00 23.16  ? 27  PHE C CB  1 
ATOM   7120  C  CG  . PHE C 1 27  ? -17.075 33.569  -56.727 1.00 25.11  ? 27  PHE C CG  1 
ATOM   7121  C  CD1 . PHE C 1 27  ? -17.246 33.696  -58.104 1.00 28.20  ? 27  PHE C CD1 1 
ATOM   7122  C  CD2 . PHE C 1 27  ? -17.889 32.690  -56.032 1.00 26.48  ? 27  PHE C CD2 1 
ATOM   7123  C  CE1 . PHE C 1 27  ? -18.226 32.969  -58.767 1.00 26.37  ? 27  PHE C CE1 1 
ATOM   7124  C  CE2 . PHE C 1 27  ? -18.868 31.964  -56.688 1.00 21.39  ? 27  PHE C CE2 1 
ATOM   7125  C  CZ  . PHE C 1 27  ? -19.039 32.105  -58.052 1.00 30.93  ? 27  PHE C CZ  1 
ATOM   7126  N  N   . ARG C 1 28  ? -14.909 32.180  -54.080 1.00 25.96  ? 28  ARG C N   1 
ATOM   7127  C  CA  . ARG C 1 28  ? -14.886 30.905  -53.372 1.00 27.48  ? 28  ARG C CA  1 
ATOM   7128  C  C   . ARG C 1 28  ? -16.265 30.589  -52.821 1.00 26.11  ? 28  ARG C C   1 
ATOM   7129  O  O   . ARG C 1 28  ? -16.995 31.494  -52.411 1.00 29.22  ? 28  ARG C O   1 
ATOM   7130  C  CB  . ARG C 1 28  ? -13.849 30.931  -52.252 1.00 27.02  ? 28  ARG C CB  1 
ATOM   7131  C  CG  . ARG C 1 28  ? -12.440 30.841  -52.771 1.00 20.26  ? 28  ARG C CG  1 
ATOM   7132  C  CD  . ARG C 1 28  ? -11.442 31.272  -51.757 1.00 20.25  ? 28  ARG C CD  1 
ATOM   7133  N  NE  . ARG C 1 28  ? -11.399 30.351  -50.626 1.00 24.07  ? 28  ARG C NE  1 
ATOM   7134  C  CZ  . ARG C 1 28  ? -11.881 30.640  -49.425 1.00 24.60  ? 28  ARG C CZ  1 
ATOM   7135  N  NH1 . ARG C 1 28  ? -12.439 31.812  -49.179 1.00 19.11  ? 28  ARG C NH1 1 
ATOM   7136  N  NH2 . ARG C 1 28  ? -11.836 29.712  -48.457 1.00 24.75  ? 28  ARG C NH2 1 
ATOM   7137  N  N   . VAL C 1 29  ? -16.632 29.305  -52.843 1.00 28.17  ? 29  VAL C N   1 
ATOM   7138  C  CA  . VAL C 1 29  ? -17.945 28.852  -52.396 1.00 29.59  ? 29  VAL C CA  1 
ATOM   7139  C  C   . VAL C 1 29  ? -17.758 27.701  -51.428 1.00 28.90  ? 29  VAL C C   1 
ATOM   7140  O  O   . VAL C 1 29  ? -17.066 26.728  -51.745 1.00 37.38  ? 29  VAL C O   1 
ATOM   7141  C  CB  . VAL C 1 29  ? -18.850 28.385  -53.547 1.00 22.84  ? 29  VAL C CB  1 
ATOM   7142  C  CG1 . VAL C 1 29  ? -20.219 27.924  -52.979 1.00 29.87  ? 29  VAL C CG1 1 
ATOM   7143  C  CG2 . VAL C 1 29  ? -19.030 29.470  -54.569 1.00 30.23  ? 29  VAL C CG2 1 
ATOM   7144  N  N   . ARG C 1 30  ? -18.430 27.763  -50.294 1.00 26.27  ? 30  ARG C N   1 
ATOM   7145  C  CA  . ARG C 1 30  ? -18.400 26.626  -49.381 1.00 25.58  ? 30  ARG C CA  1 
ATOM   7146  C  C   . ARG C 1 30  ? -19.522 25.643  -49.681 1.00 26.79  ? 30  ARG C C   1 
ATOM   7147  O  O   . ARG C 1 30  ? -20.642 26.024  -50.023 1.00 26.51  ? 30  ARG C O   1 
ATOM   7148  C  CB  . ARG C 1 30  ? -18.435 27.088  -47.919 1.00 34.79  ? 30  ARG C CB  1 
ATOM   7149  C  CG  . ARG C 1 30  ? -19.585 27.958  -47.484 1.00 36.47  ? 30  ARG C CG  1 
ATOM   7150  C  CD  . ARG C 1 30  ? -19.700 27.885  -45.941 1.00 36.50  ? 30  ARG C CD  1 
ATOM   7151  N  NE  . ARG C 1 30  ? -20.544 26.784  -45.506 1.00 41.69  ? 30  ARG C NE  1 
ATOM   7152  C  CZ  . ARG C 1 30  ? -21.838 26.873  -45.221 1.00 34.69  ? 30  ARG C CZ  1 
ATOM   7153  N  NH1 . ARG C 1 30  ? -22.468 28.036  -45.192 1.00 45.37  ? 30  ARG C NH1 1 
ATOM   7154  N  NH2 . ARG C 1 30  ? -22.518 25.765  -44.970 1.00 38.12  ? 30  ARG C NH2 1 
ATOM   7155  N  N   . MET C 1 31  ? -19.183 24.369  -49.599 1.00 33.82  ? 31  MET C N   1 
ATOM   7156  C  CA  . MET C 1 31  ? -20.129 23.290  -49.796 1.00 29.29  ? 31  MET C CA  1 
ATOM   7157  C  C   . MET C 1 31  ? -21.380 23.530  -48.951 1.00 33.19  ? 31  MET C C   1 
ATOM   7158  O  O   . MET C 1 31  ? -21.258 23.746  -47.736 1.00 33.01  ? 31  MET C O   1 
ATOM   7159  C  CB  . MET C 1 31  ? -19.459 21.982  -49.371 1.00 35.25  ? 31  MET C CB  1 
ATOM   7160  C  CG  . MET C 1 31  ? -20.279 20.718  -49.561 1.00 27.71  ? 31  MET C CG  1 
ATOM   7161  S  SD  . MET C 1 31  ? -21.293 20.759  -51.032 1.00 35.55  ? 31  MET C SD  1 
ATOM   7162  C  CE  . MET C 1 31  ? -20.382 19.573  -51.990 1.00 24.20  ? 31  MET C CE  1 
ATOM   7163  N  N   . PRO C 1 32  ? -22.608 23.509  -49.554 1.00 29.42  ? 32  PRO C N   1 
ATOM   7164  C  CA  . PRO C 1 32  ? -23.828 23.701  -48.745 1.00 33.01  ? 32  PRO C CA  1 
ATOM   7165  C  C   . PRO C 1 32  ? -24.424 22.407  -48.233 1.00 29.44  ? 32  PRO C C   1 
ATOM   7166  O  O   . PRO C 1 32  ? -25.253 22.429  -47.328 1.00 31.51  ? 32  PRO C O   1 
ATOM   7167  C  CB  . PRO C 1 32  ? -24.798 24.381  -49.716 1.00 29.18  ? 32  PRO C CB  1 
ATOM   7168  C  CG  . PRO C 1 32  ? -24.391 23.851  -51.047 1.00 33.02  ? 32  PRO C CG  1 
ATOM   7169  C  CD  . PRO C 1 32  ? -22.876 23.714  -50.991 1.00 31.03  ? 32  PRO C CD  1 
ATOM   7170  N  N   . SER C 1 33  ? -24.047 21.295  -48.851 1.00 25.67  ? 33  SER C N   1 
ATOM   7171  C  CA  . SER C 1 33  ? -24.457 19.972  -48.429 1.00 29.53  ? 33  SER C CA  1 
ATOM   7172  C  C   . SER C 1 33  ? -23.770 19.597  -47.111 1.00 31.72  ? 33  SER C C   1 
ATOM   7173  O  O   . SER C 1 33  ? -22.832 20.254  -46.644 1.00 30.56  ? 33  SER C O   1 
ATOM   7174  C  CB  . SER C 1 33  ? -24.132 18.967  -49.531 1.00 32.80  ? 33  SER C CB  1 
ATOM   7175  O  OG  . SER C 1 33  ? -24.536 17.669  -49.193 1.00 34.57  ? 33  SER C OG  1 
ATOM   7176  N  N   . TYR C 1 34  ? -24.247 18.527  -46.494 1.00 35.79  ? 34  TYR C N   1 
ATOM   7177  C  CA  . TYR C 1 34  ? -23.704 18.127  -45.204 1.00 34.98  ? 34  TYR C CA  1 
ATOM   7178  C  C   . TYR C 1 34  ? -22.478 17.227  -45.314 1.00 36.53  ? 34  TYR C C   1 
ATOM   7179  O  O   . TYR C 1 34  ? -22.011 16.720  -44.287 1.00 33.37  ? 34  TYR C O   1 
ATOM   7180  C  CB  . TYR C 1 34  ? -24.790 17.449  -44.355 1.00 39.45  ? 34  TYR C CB  1 
ATOM   7181  C  CG  . TYR C 1 34  ? -25.711 16.492  -45.072 1.00 40.25  ? 34  TYR C CG  1 
ATOM   7182  C  CD1 . TYR C 1 34  ? -25.215 15.396  -45.757 1.00 37.98  ? 34  TYR C CD1 1 
ATOM   7183  C  CD2 . TYR C 1 34  ? -27.095 16.685  -45.049 1.00 47.23  ? 34  TYR C CD2 1 
ATOM   7184  C  CE1 . TYR C 1 34  ? -26.070 14.508  -46.396 1.00 43.45  ? 34  TYR C CE1 1 
ATOM   7185  C  CE2 . TYR C 1 34  ? -27.958 15.802  -45.685 1.00 44.38  ? 34  TYR C CE2 1 
ATOM   7186  C  CZ  . TYR C 1 34  ? -27.437 14.718  -46.349 1.00 44.82  ? 34  TYR C CZ  1 
ATOM   7187  O  OH  . TYR C 1 34  ? -28.275 13.845  -46.984 1.00 46.82  ? 34  TYR C OH  1 
ATOM   7188  N  N   . ARG C 1 35  ? -21.949 17.026  -46.522 1.00 30.27  ? 35  ARG C N   1 
ATOM   7189  C  CA  . ARG C 1 35  ? -20.729 16.261  -46.743 1.00 24.90  ? 35  ARG C CA  1 
ATOM   7190  C  C   . ARG C 1 35  ? -19.986 16.859  -47.939 1.00 30.05  ? 35  ARG C C   1 
ATOM   7191  O  O   . ARG C 1 35  ? -20.578 17.548  -48.772 1.00 28.00  ? 35  ARG C O   1 
ATOM   7192  C  CB  . ARG C 1 35  ? -21.048 14.785  -46.999 1.00 33.31  ? 35  ARG C CB  1 
ATOM   7193  C  CG  . ARG C 1 35  ? -21.956 14.601  -48.189 1.00 27.50  ? 35  ARG C CG  1 
ATOM   7194  C  CD  . ARG C 1 35  ? -21.777 13.249  -48.829 1.00 32.14  ? 35  ARG C CD  1 
ATOM   7195  N  NE  . ARG C 1 35  ? -22.755 13.034  -49.884 1.00 25.94  ? 35  ARG C NE  1 
ATOM   7196  C  CZ  . ARG C 1 35  ? -22.632 12.142  -50.857 1.00 24.80  ? 35  ARG C CZ  1 
ATOM   7197  N  NH1 . ARG C 1 35  ? -21.573 11.355  -50.945 1.00 25.55  ? 35  ARG C NH1 1 
ATOM   7198  N  NH2 . ARG C 1 35  ? -23.616 12.011  -51.740 1.00 26.79  ? 35  ARG C NH2 1 
ATOM   7199  N  N   . GLY C 1 36  ? -18.675 16.609  -48.004 1.00 28.20  ? 36  GLY C N   1 
ATOM   7200  C  CA  . GLY C 1 36  ? -17.989 16.687  -49.270 1.00 28.27  ? 36  GLY C CA  1 
ATOM   7201  C  C   . GLY C 1 36  ? -18.489 15.599  -50.200 1.00 29.53  ? 36  GLY C C   1 
ATOM   7202  O  O   . GLY C 1 36  ? -19.063 14.604  -49.760 1.00 28.69  ? 36  GLY C O   1 
ATOM   7203  N  N   . MET C 1 37  ? -18.278 15.795  -51.501 1.00 26.29  ? 37  MET C N   1 
ATOM   7204  C  CA  . MET C 1 37  ? -18.792 14.874  -52.509 1.00 31.65  ? 37  MET C CA  1 
ATOM   7205  C  C   . MET C 1 37  ? -17.798 14.695  -53.642 1.00 28.35  ? 37  MET C C   1 
ATOM   7206  O  O   . MET C 1 37  ? -16.906 15.526  -53.863 1.00 27.90  ? 37  MET C O   1 
ATOM   7207  C  CB  . MET C 1 37  ? -20.132 15.321  -53.150 1.00 33.17  ? 37  MET C CB  1 
ATOM   7208  C  CG  . MET C 1 37  ? -21.056 16.223  -52.325 1.00 40.21  ? 37  MET C CG  1 
ATOM   7209  S  SD  . MET C 1 37  ? -22.603 16.581  -53.207 1.00 41.98  ? 37  MET C SD  1 
ATOM   7210  C  CE  . MET C 1 37  ? -23.539 15.082  -52.901 1.00 38.54  ? 37  MET C CE  1 
ATOM   7211  N  N   . ALA C 1 38  ? -17.991 13.584  -54.374 1.00 30.25  ? 38  ALA C N   1 
ATOM   7212  C  CA  . ALA C 1 38  ? -17.265 13.354  -55.617 1.00 25.34  ? 38  ALA C CA  1 
ATOM   7213  C  C   . ALA C 1 38  ? -17.584 14.476  -56.592 1.00 24.42  ? 38  ALA C C   1 
ATOM   7214  O  O   . ALA C 1 38  ? -18.753 14.828  -56.770 1.00 23.60  ? 38  ALA C O   1 
ATOM   7215  C  CB  . ALA C 1 38  ? -17.655 12.007  -56.215 1.00 25.02  ? 38  ALA C CB  1 
ATOM   7216  N  N   . ALA C 1 39  ? -16.544 15.058  -57.204 1.00 23.64  ? 39  ALA C N   1 
ATOM   7217  C  CA  . ALA C 1 39  ? -16.749 16.236  -58.055 1.00 27.27  ? 39  ALA C CA  1 
ATOM   7218  C  C   . ALA C 1 39  ? -17.626 15.960  -59.279 1.00 26.35  ? 39  ALA C C   1 
ATOM   7219  O  O   . ALA C 1 39  ? -18.196 16.903  -59.837 1.00 27.22  ? 39  ALA C O   1 
ATOM   7220  C  CB  . ALA C 1 39  ? -15.399 16.806  -58.508 1.00 27.68  ? 39  ALA C CB  1 
ATOM   7221  N  N   . SER C 1 40  ? -17.761 14.703  -59.707 1.00 31.00  ? 40  SER C N   1 
ATOM   7222  C  CA  . SER C 1 40  ? -18.632 14.390  -60.837 1.00 27.83  ? 40  SER C CA  1 
ATOM   7223  C  C   . SER C 1 40  ? -20.102 14.645  -60.526 1.00 29.58  ? 40  SER C C   1 
ATOM   7224  O  O   . SER C 1 40  ? -20.904 14.775  -61.455 1.00 30.08  ? 40  SER C O   1 
ATOM   7225  C  CB  . SER C 1 40  ? -18.435 12.934  -61.279 1.00 31.03  ? 40  SER C CB  1 
ATOM   7226  O  OG  . SER C 1 40  ? -18.833 11.994  -60.284 1.00 27.25  ? 40  SER C OG  1 
ATOM   7227  N  N   . LEU C 1 41  ? -20.461 14.733  -59.247 1.00 26.71  ? 41  LEU C N   1 
ATOM   7228  C  CA  . LEU C 1 41  ? -21.826 15.000  -58.812 1.00 28.16  ? 41  LEU C CA  1 
ATOM   7229  C  C   . LEU C 1 41  ? -22.162 16.483  -58.799 1.00 28.62  ? 41  LEU C C   1 
ATOM   7230  O  O   . LEU C 1 41  ? -23.306 16.842  -58.496 1.00 33.22  ? 41  LEU C O   1 
ATOM   7231  C  CB  . LEU C 1 41  ? -22.053 14.418  -57.420 1.00 29.15  ? 41  LEU C CB  1 
ATOM   7232  C  CG  . LEU C 1 41  ? -22.149 12.894  -57.372 1.00 31.03  ? 41  LEU C CG  1 
ATOM   7233  C  CD1 . LEU C 1 41  ? -21.900 12.394  -55.935 1.00 31.32  ? 41  LEU C CD1 1 
ATOM   7234  C  CD2 . LEU C 1 41  ? -23.501 12.431  -57.896 1.00 32.22  ? 41  LEU C CD2 1 
ATOM   7235  N  N   . ILE C 1 42  ? -21.193 17.345  -59.090 1.00 27.14  ? 42  ILE C N   1 
ATOM   7236  C  CA  . ILE C 1 42  ? -21.474 18.748  -59.347 1.00 24.44  ? 42  ILE C CA  1 
ATOM   7237  C  C   . ILE C 1 42  ? -22.225 18.872  -60.671 1.00 31.08  ? 42  ILE C C   1 
ATOM   7238  O  O   . ILE C 1 42  ? -21.913 18.184  -61.654 1.00 30.52  ? 42  ILE C O   1 
ATOM   7239  C  CB  . ILE C 1 42  ? -20.165 19.554  -59.367 1.00 28.19  ? 42  ILE C CB  1 
ATOM   7240  C  CG1 . ILE C 1 42  ? -19.584 19.726  -57.953 1.00 28.76  ? 42  ILE C CG1 1 
ATOM   7241  C  CG2 . ILE C 1 42  ? -20.400 20.913  -59.995 1.00 28.43  ? 42  ILE C CG2 1 
ATOM   7242  C  CD1 . ILE C 1 42  ? -18.038 19.718  -57.908 1.00 22.40  ? 42  ILE C CD1 1 
ATOM   7243  N  N   . ASP C 1 43  ? -23.251 19.713  -60.701 1.00 29.33  ? 43  ASP C N   1 
ATOM   7244  C  CA  . ASP C 1 43  ? -24.010 19.915  -61.927 1.00 31.79  ? 43  ASP C CA  1 
ATOM   7245  C  C   . ASP C 1 43  ? -23.919 21.354  -62.414 1.00 34.95  ? 43  ASP C C   1 
ATOM   7246  O  O   . ASP C 1 43  ? -24.654 21.733  -63.328 1.00 35.41  ? 43  ASP C O   1 
ATOM   7247  C  CB  . ASP C 1 43  ? -25.483 19.523  -61.740 1.00 33.16  ? 43  ASP C CB  1 
ATOM   7248  C  CG  . ASP C 1 43  ? -25.892 18.294  -62.552 1.00 32.58  ? 43  ASP C CG  1 
ATOM   7249  O  OD1 . ASP C 1 43  ? -25.062 17.668  -63.250 1.00 35.83  ? 43  ASP C OD1 1 
ATOM   7250  O  OD2 . ASP C 1 43  ? -27.090 17.961  -62.524 1.00 45.05  ? 43  ASP C OD2 1 
ATOM   7251  N  N   . GLY C 1 44  ? -23.065 22.171  -61.817 1.00 26.94  ? 44  GLY C N   1 
ATOM   7252  C  CA  . GLY C 1 44  ? -22.751 23.480  -62.351 1.00 32.41  ? 44  GLY C CA  1 
ATOM   7253  C  C   . GLY C 1 44  ? -23.100 24.588  -61.378 1.00 34.69  ? 44  GLY C C   1 
ATOM   7254  O  O   . GLY C 1 44  ? -23.605 24.358  -60.281 1.00 32.41  ? 44  GLY C O   1 
ATOM   7255  N  N   . ILE C 1 45  ? -22.822 25.813  -61.820 1.00 26.80  ? 45  ILE C N   1 
ATOM   7256  C  CA  . ILE C 1 45  ? -23.078 27.014  -61.042 1.00 29.51  ? 45  ILE C CA  1 
ATOM   7257  C  C   . ILE C 1 45  ? -23.246 28.142  -62.052 1.00 29.02  ? 45  ILE C C   1 
ATOM   7258  O  O   . ILE C 1 45  ? -22.310 28.478  -62.781 1.00 31.22  ? 45  ILE C O   1 
ATOM   7259  C  CB  . ILE C 1 45  ? -21.959 27.279  -60.012 1.00 27.28  ? 45  ILE C CB  1 
ATOM   7260  C  CG1 . ILE C 1 45  ? -22.184 28.608  -59.292 1.00 27.63  ? 45  ILE C CG1 1 
ATOM   7261  C  CG2 . ILE C 1 45  ? -20.593 27.265  -60.658 1.00 28.79  ? 45  ILE C CG2 1 
ATOM   7262  C  CD1 . ILE C 1 45  ? -21.382 28.762  -58.043 1.00 26.62  ? 45  ILE C CD1 1 
ATOM   7263  N  N   . GLY C 1 46  ? -24.448 28.707  -62.129 1.00 30.90  ? 46  GLY C N   1 
ATOM   7264  C  CA  . GLY C 1 46  ? -24.645 29.947  -62.846 1.00 32.36  ? 46  GLY C CA  1 
ATOM   7265  C  C   . GLY C 1 46  ? -24.214 31.122  -61.992 1.00 34.56  ? 46  GLY C C   1 
ATOM   7266  O  O   . GLY C 1 46  ? -24.296 31.086  -60.769 1.00 32.84  ? 46  GLY C O   1 
ATOM   7267  N  N   . VAL C 1 47  ? -23.724 32.169  -62.649 1.00 33.59  ? 47  VAL C N   1 
ATOM   7268  C  CA  . VAL C 1 47  ? -23.111 33.304  -61.967 1.00 35.55  ? 47  VAL C CA  1 
ATOM   7269  C  C   . VAL C 1 47  ? -23.633 34.595  -62.585 1.00 36.97  ? 47  VAL C C   1 
ATOM   7270  O  O   . VAL C 1 47  ? -23.756 34.704  -63.811 1.00 37.62  ? 47  VAL C O   1 
ATOM   7271  C  CB  . VAL C 1 47  ? -21.566 33.248  -62.041 1.00 34.52  ? 47  VAL C CB  1 
ATOM   7272  C  CG1 . VAL C 1 47  ? -20.954 34.443  -61.334 1.00 32.29  ? 47  VAL C CG1 1 
ATOM   7273  C  CG2 . VAL C 1 47  ? -21.049 31.966  -61.433 1.00 33.27  ? 47  VAL C CG2 1 
ATOM   7274  N  N   . ARG C 1 48  ? -23.921 35.580  -61.735 1.00 33.55  ? 48  ARG C N   1 
ATOM   7275  C  CA  . ARG C 1 48  ? -24.482 36.835  -62.206 1.00 34.74  ? 48  ARG C CA  1 
ATOM   7276  C  C   . ARG C 1 48  ? -24.029 37.998  -61.335 1.00 38.52  ? 48  ARG C C   1 
ATOM   7277  O  O   . ARG C 1 48  ? -24.108 37.935  -60.103 1.00 36.11  ? 48  ARG C O   1 
ATOM   7278  C  CB  . ARG C 1 48  ? -26.009 36.761  -62.236 1.00 40.67  ? 48  ARG C CB  1 
ATOM   7279  C  CG  . ARG C 1 48  ? -26.667 37.986  -62.834 1.00 42.96  ? 48  ARG C CG  1 
ATOM   7280  C  CD  . ARG C 1 48  ? -27.803 37.590  -63.749 1.00 52.79  ? 48  ARG C CD  1 
ATOM   7281  N  NE  . ARG C 1 48  ? -28.866 38.587  -63.762 1.00 62.93  ? 48  ARG C NE  1 
ATOM   7282  C  CZ  . ARG C 1 48  ? -30.160 38.297  -63.800 1.00 60.29  ? 48  ARG C CZ  1 
ATOM   7283  N  NH1 . ARG C 1 48  ? -30.587 37.044  -63.845 1.00 69.05  ? 48  ARG C NH1 1 
ATOM   7284  N  NH2 . ARG C 1 48  ? -31.047 39.288  -63.794 1.00 57.89  ? 48  ARG C NH2 1 
ATOM   7285  N  N   . ILE C 1 49  ? -23.521 39.037  -61.987 1.00 37.92  ? 49  ILE C N   1 
ATOM   7286  C  CA  . ILE C 1 49  ? -23.452 40.380  -61.425 1.00 37.02  ? 49  ILE C CA  1 
ATOM   7287  C  C   . ILE C 1 49  ? -24.236 41.245  -62.406 1.00 43.23  ? 49  ILE C C   1 
ATOM   7288  O  O   . ILE C 1 49  ? -23.824 41.370  -63.572 1.00 40.47  ? 49  ILE C O   1 
ATOM   7289  C  CB  . ILE C 1 49  ? -22.006 40.866  -61.247 1.00 34.85  ? 49  ILE C CB  1 
ATOM   7290  C  CG1 . ILE C 1 49  ? -21.289 40.094  -60.141 1.00 36.14  ? 49  ILE C CG1 1 
ATOM   7291  C  CG2 . ILE C 1 49  ? -21.974 42.332  -60.906 1.00 39.42  ? 49  ILE C CG2 1 
ATOM   7292  C  CD1 . ILE C 1 49  ? -19.818 39.919  -60.398 1.00 28.00  ? 49  ILE C CD1 1 
ATOM   7293  N  N   . PRO C 1 50  ? -25.386 41.795  -62.002 1.00 43.03  ? 50  PRO C N   1 
ATOM   7294  C  CA  . PRO C 1 50  ? -26.200 42.614  -62.914 1.00 47.11  ? 50  PRO C CA  1 
ATOM   7295  C  C   . PRO C 1 50  ? -25.394 43.683  -63.637 1.00 42.57  ? 50  PRO C C   1 
ATOM   7296  O  O   . PRO C 1 50  ? -24.665 44.468  -63.022 1.00 38.48  ? 50  PRO C O   1 
ATOM   7297  C  CB  . PRO C 1 50  ? -27.243 43.246  -61.982 1.00 48.73  ? 50  PRO C CB  1 
ATOM   7298  C  CG  . PRO C 1 50  ? -27.196 42.465  -60.686 1.00 40.78  ? 50  PRO C CG  1 
ATOM   7299  C  CD  . PRO C 1 50  ? -26.145 41.399  -60.805 1.00 43.71  ? 50  PRO C CD  1 
ATOM   7300  N  N   . GLY C 1 51  ? -25.543 43.719  -64.960 1.00 40.34  ? 51  GLY C N   1 
ATOM   7301  C  CA  . GLY C 1 51  ? -24.862 44.702  -65.765 1.00 35.80  ? 51  GLY C CA  1 
ATOM   7302  C  C   . GLY C 1 51  ? -23.430 44.369  -66.107 1.00 41.67  ? 51  GLY C C   1 
ATOM   7303  O  O   . GLY C 1 51  ? -22.841 45.052  -66.953 1.00 35.69  ? 51  GLY C O   1 
ATOM   7304  N  N   . LEU C 1 52  ? -22.847 43.338  -65.495 1.00 39.33  ? 52  LEU C N   1 
ATOM   7305  C  CA  . LEU C 1 52  ? -21.469 42.961  -65.780 1.00 36.53  ? 52  LEU C CA  1 
ATOM   7306  C  C   . LEU C 1 52  ? -21.320 41.512  -66.222 1.00 33.66  ? 52  LEU C C   1 
ATOM   7307  O  O   . LEU C 1 52  ? -20.522 41.229  -67.111 1.00 36.41  ? 52  LEU C O   1 
ATOM   7308  C  CB  . LEU C 1 52  ? -20.588 43.213  -64.540 1.00 36.33  ? 52  LEU C CB  1 
ATOM   7309  C  CG  . LEU C 1 52  ? -20.414 44.659  -64.086 1.00 32.73  ? 52  LEU C CG  1 
ATOM   7310  C  CD1 . LEU C 1 52  ? -19.692 44.723  -62.766 1.00 38.38  ? 52  LEU C CD1 1 
ATOM   7311  C  CD2 . LEU C 1 52  ? -19.634 45.450  -65.113 1.00 38.34  ? 52  LEU C CD2 1 
ATOM   7312  N  N   . VAL C 1 53  ? -22.064 40.581  -65.626 1.00 38.71  ? 53  VAL C N   1 
ATOM   7313  C  CA  . VAL C 1 53  ? -21.818 39.151  -65.805 1.00 37.86  ? 53  VAL C CA  1 
ATOM   7314  C  C   . VAL C 1 53  ? -23.142 38.408  -65.767 1.00 36.34  ? 53  VAL C C   1 
ATOM   7315  O  O   . VAL C 1 53  ? -23.956 38.627  -64.867 1.00 36.87  ? 53  VAL C O   1 
ATOM   7316  C  CB  . VAL C 1 53  ? -20.875 38.587  -64.717 1.00 41.14  ? 53  VAL C CB  1 
ATOM   7317  C  CG1 . VAL C 1 53  ? -20.755 37.081  -64.841 1.00 43.05  ? 53  VAL C CG1 1 
ATOM   7318  C  CG2 . VAL C 1 53  ? -19.499 39.198  -64.819 1.00 36.51  ? 53  VAL C CG2 1 
ATOM   7319  N  N   . ASP C 1 54  ? -23.354 37.512  -66.733 1.00 34.03  ? 54  ASP C N   1 
ATOM   7320  C  CA  . ASP C 1 54  ? -24.452 36.547  -66.635 1.00 42.05  ? 54  ASP C CA  1 
ATOM   7321  C  C   . ASP C 1 54  ? -24.080 35.347  -67.494 1.00 45.23  ? 54  ASP C C   1 
ATOM   7322  O  O   . ASP C 1 54  ? -24.134 35.433  -68.728 1.00 44.17  ? 54  ASP C O   1 
ATOM   7323  C  CB  . ASP C 1 54  ? -25.777 37.161  -67.082 1.00 45.37  ? 54  ASP C CB  1 
ATOM   7324  C  CG  . ASP C 1 54  ? -26.890 36.126  -67.217 1.00 53.59  ? 54  ASP C CG  1 
ATOM   7325  O  OD1 . ASP C 1 54  ? -26.772 35.011  -66.669 1.00 51.76  ? 54  ASP C OD1 1 
ATOM   7326  O  OD2 . ASP C 1 54  ? -27.892 36.419  -67.901 1.00 62.51  ? 54  ASP C OD2 1 
ATOM   7327  N  N   . VAL C 1 55  ? -23.695 34.239  -66.842 1.00 41.48  ? 55  VAL C N   1 
ATOM   7328  C  CA  . VAL C 1 55  ? -23.320 33.002  -67.521 1.00 38.72  ? 55  VAL C CA  1 
ATOM   7329  C  C   . VAL C 1 55  ? -24.046 31.852  -66.850 1.00 31.41  ? 55  VAL C C   1 
ATOM   7330  O  O   . VAL C 1 55  ? -24.325 31.890  -65.650 1.00 35.87  ? 55  VAL C O   1 
ATOM   7331  C  CB  . VAL C 1 55  ? -21.794 32.742  -67.516 1.00 34.72  ? 55  VAL C CB  1 
ATOM   7332  C  CG1 . VAL C 1 55  ? -21.069 33.777  -68.352 1.00 40.97  ? 55  VAL C CG1 1 
ATOM   7333  C  CG2 . VAL C 1 55  ? -21.255 32.737  -66.109 1.00 34.89  ? 55  VAL C CG2 1 
ATOM   7334  N  N   . GLY C 1 56  ? -24.350 30.821  -67.635 1.00 29.93  ? 56  GLY C N   1 
ATOM   7335  C  CA  . GLY C 1 56  ? -25.095 29.682  -67.143 1.00 36.21  ? 56  GLY C CA  1 
ATOM   7336  C  C   . GLY C 1 56  ? -24.214 28.660  -66.444 1.00 33.91  ? 56  GLY C C   1 
ATOM   7337  O  O   . GLY C 1 56  ? -22.980 28.773  -66.386 1.00 32.95  ? 56  GLY C O   1 
ATOM   7338  N  N   . PRO C 1 57  ? -24.858 27.625  -65.896 1.00 39.46  ? 57  PRO C N   1 
ATOM   7339  C  CA  . PRO C 1 57  ? -24.138 26.710  -64.990 1.00 31.30  ? 57  PRO C CA  1 
ATOM   7340  C  C   . PRO C 1 57  ? -22.933 26.014  -65.609 1.00 34.56  ? 57  PRO C C   1 
ATOM   7341  O  O   . PRO C 1 57  ? -22.038 25.594  -64.868 1.00 35.62  ? 57  PRO C O   1 
ATOM   7342  C  CB  . PRO C 1 57  ? -25.219 25.698  -64.581 1.00 33.96  ? 57  PRO C CB  1 
ATOM   7343  C  CG  . PRO C 1 57  ? -26.298 25.828  -65.631 1.00 41.33  ? 57  PRO C CG  1 
ATOM   7344  C  CD  . PRO C 1 57  ? -26.284 27.269  -66.031 1.00 39.91  ? 57  PRO C CD  1 
ATOM   7345  N  N   . ASP C 1 58  ? -22.853 25.880  -66.930 1.00 37.46  ? 58  ASP C N   1 
ATOM   7346  C  CA  . ASP C 1 58  ? -21.766 25.104  -67.504 1.00 33.00  ? 58  ASP C CA  1 
ATOM   7347  C  C   . ASP C 1 58  ? -20.538 25.943  -67.832 1.00 33.47  ? 58  ASP C C   1 
ATOM   7348  O  O   . ASP C 1 58  ? -19.534 25.390  -68.291 1.00 33.34  ? 58  ASP C O   1 
ATOM   7349  C  CB  . ASP C 1 58  ? -22.247 24.356  -68.749 1.00 37.90  ? 58  ASP C CB  1 
ATOM   7350  C  CG  . ASP C 1 58  ? -22.859 25.273  -69.781 1.00 41.74  ? 58  ASP C CG  1 
ATOM   7351  O  OD1 . ASP C 1 58  ? -23.248 26.408  -69.418 1.00 43.36  ? 58  ASP C OD1 1 
ATOM   7352  O  OD2 . ASP C 1 58  ? -22.961 24.847  -70.956 1.00 50.24  ? 58  ASP C OD2 1 
ATOM   7353  N  N   . VAL C 1 59  ? -20.560 27.245  -67.569 1.00 32.17  ? 59  VAL C N   1 
ATOM   7354  C  CA  . VAL C 1 59  ? -19.489 28.102  -68.068 1.00 31.04  ? 59  VAL C CA  1 
ATOM   7355  C  C   . VAL C 1 59  ? -18.330 28.233  -67.079 1.00 28.10  ? 59  VAL C C   1 
ATOM   7356  O  O   . VAL C 1 59  ? -17.174 28.124  -67.506 1.00 29.09  ? 59  VAL C O   1 
ATOM   7357  C  CB  . VAL C 1 59  ? -20.042 29.479  -68.482 1.00 36.02  ? 59  VAL C CB  1 
ATOM   7358  C  CG1 . VAL C 1 59  ? -18.928 30.497  -68.593 1.00 30.68  ? 59  VAL C CG1 1 
ATOM   7359  C  CG2 . VAL C 1 59  ? -20.766 29.364  -69.803 1.00 34.58  ? 59  VAL C CG2 1 
ATOM   7360  N  N   . PRO C 1 60  ? -18.538 28.468  -65.779 1.00 31.18  ? 60  PRO C N   1 
ATOM   7361  C  CA  . PRO C 1 60  ? -17.373 28.684  -64.904 1.00 26.55  ? 60  PRO C CA  1 
ATOM   7362  C  C   . PRO C 1 60  ? -16.493 27.447  -64.793 1.00 23.40  ? 60  PRO C C   1 
ATOM   7363  O  O   . PRO C 1 60  ? -16.956 26.313  -64.939 1.00 24.99  ? 60  PRO C O   1 
ATOM   7364  C  CB  . PRO C 1 60  ? -18.001 29.046  -63.551 1.00 31.62  ? 60  PRO C CB  1 
ATOM   7365  C  CG  . PRO C 1 60  ? -19.372 29.583  -63.915 1.00 32.95  ? 60  PRO C CG  1 
ATOM   7366  C  CD  . PRO C 1 60  ? -19.802 28.724  -65.063 1.00 26.97  ? 60  PRO C CD  1 
ATOM   7367  N  N   . LEU C 1 61  ? -15.201 27.684  -64.544 1.00 26.21  ? 61  LEU C N   1 
ATOM   7368  C  CA  . LEU C 1 61  ? -14.227 26.640  -64.234 1.00 26.21  ? 61  LEU C CA  1 
ATOM   7369  C  C   . LEU C 1 61  ? -14.139 26.403  -62.720 1.00 29.07  ? 61  LEU C C   1 
ATOM   7370  O  O   . LEU C 1 61  ? -14.494 27.260  -61.900 1.00 25.38  ? 61  LEU C O   1 
ATOM   7371  C  CB  . LEU C 1 61  ? -12.846 27.010  -64.767 1.00 23.29  ? 61  LEU C CB  1 
ATOM   7372  C  CG  . LEU C 1 61  ? -12.826 27.419  -66.239 1.00 28.93  ? 61  LEU C CG  1 
ATOM   7373  C  CD1 . LEU C 1 61  ? -11.408 27.779  -66.715 1.00 27.16  ? 61  LEU C CD1 1 
ATOM   7374  C  CD2 . LEU C 1 61  ? -13.410 26.310  -67.038 1.00 25.32  ? 61  LEU C CD2 1 
ATOM   7375  N  N   . TRP C 1 62  ? -13.639 25.224  -62.350 1.00 28.26  ? 62  TRP C N   1 
ATOM   7376  C  CA  . TRP C 1 62  ? -13.650 24.794  -60.954 1.00 27.64  ? 62  TRP C CA  1 
ATOM   7377  C  C   . TRP C 1 62  ? -12.264 24.339  -60.552 1.00 21.63  ? 62  TRP C C   1 
ATOM   7378  O  O   . TRP C 1 62  ? -11.744 23.380  -61.119 1.00 22.69  ? 62  TRP C O   1 
ATOM   7379  C  CB  . TRP C 1 62  ? -14.632 23.647  -60.737 1.00 25.40  ? 62  TRP C CB  1 
ATOM   7380  C  CG  . TRP C 1 62  ? -16.064 23.972  -60.823 1.00 26.44  ? 62  TRP C CG  1 
ATOM   7381  C  CD1 . TRP C 1 62  ? -16.755 24.339  -61.932 1.00 30.40  ? 62  TRP C CD1 1 
ATOM   7382  C  CD2 . TRP C 1 62  ? -17.018 23.914  -59.755 1.00 31.51  ? 62  TRP C CD2 1 
ATOM   7383  N  NE1 . TRP C 1 62  ? -18.085 24.520  -61.625 1.00 25.95  ? 62  TRP C NE1 1 
ATOM   7384  C  CE2 . TRP C 1 62  ? -18.268 24.262  -60.291 1.00 30.56  ? 62  TRP C CE2 1 
ATOM   7385  C  CE3 . TRP C 1 62  ? -16.931 23.616  -58.392 1.00 29.79  ? 62  TRP C CE3 1 
ATOM   7386  C  CZ2 . TRP C 1 62  ? -19.424 24.314  -59.514 1.00 23.62  ? 62  TRP C CZ2 1 
ATOM   7387  C  CZ3 . TRP C 1 62  ? -18.071 23.661  -57.630 1.00 28.43  ? 62  TRP C CZ3 1 
ATOM   7388  C  CH2 . TRP C 1 62  ? -19.303 24.012  -58.191 1.00 31.73  ? 62  TRP C CH2 1 
ATOM   7389  N  N   . THR C 1 63  ? -11.667 24.997  -59.565 1.00 25.49  ? 63  THR C N   1 
ATOM   7390  C  CA  . THR C 1 63  ? -10.437 24.494  -58.970 1.00 21.35  ? 63  THR C CA  1 
ATOM   7391  C  C   . THR C 1 63  ? -10.802 23.693  -57.717 1.00 23.58  ? 63  THR C C   1 
ATOM   7392  O  O   . THR C 1 63  ? -11.402 24.226  -56.781 1.00 23.41  ? 63  THR C O   1 
ATOM   7393  C  CB  . THR C 1 63  ? -9.471  25.641  -58.693 1.00 22.88  ? 63  THR C CB  1 
ATOM   7394  O  OG1 . THR C 1 63  ? -9.164  26.242  -59.955 1.00 21.05  ? 63  THR C OG1 1 
ATOM   7395  C  CG2 . THR C 1 63  ? -8.167  25.137  -58.080 1.00 23.32  ? 63  THR C CG2 1 
ATOM   7396  N  N   . LEU C 1 64  ? -10.506 22.395  -57.747 1.00 25.11  ? 64  LEU C N   1 
ATOM   7397  C  CA  . LEU C 1 64  ? -10.776 21.470  -56.655 1.00 24.45  ? 64  LEU C CA  1 
ATOM   7398  C  C   . LEU C 1 64  ? -9.550  20.599  -56.468 1.00 28.72  ? 64  LEU C C   1 
ATOM   7399  O  O   . LEU C 1 64  ? -9.062  20.001  -57.435 1.00 26.92  ? 64  LEU C O   1 
ATOM   7400  C  CB  . LEU C 1 64  ? -11.999 20.589  -56.953 1.00 23.45  ? 64  LEU C CB  1 
ATOM   7401  C  CG  . LEU C 1 64  ? -13.340 21.291  -57.110 1.00 22.59  ? 64  LEU C CG  1 
ATOM   7402  C  CD1 . LEU C 1 64  ? -14.370 20.383  -57.744 1.00 23.35  ? 64  LEU C CD1 1 
ATOM   7403  C  CD2 . LEU C 1 64  ? -13.847 21.798  -55.758 1.00 27.08  ? 64  LEU C CD2 1 
ATOM   7404  N  N   . GLN C 1 65  ? -9.057  20.528  -55.231 1.00 29.85  ? 65  GLN C N   1 
ATOM   7405  C  CA  . GLN C 1 65  ? -7.867  19.745  -54.908 1.00 24.14  ? 65  GLN C CA  1 
ATOM   7406  C  C   . GLN C 1 65  ? -6.716  20.057  -55.871 1.00 30.82  ? 65  GLN C C   1 
ATOM   7407  O  O   . GLN C 1 65  ? -6.132  19.163  -56.490 1.00 30.60  ? 65  GLN C O   1 
ATOM   7408  C  CB  . GLN C 1 65  ? -8.203  18.250  -54.908 1.00 28.01  ? 65  GLN C CB  1 
ATOM   7409  C  CG  . GLN C 1 65  ? -9.423  17.879  -54.050 1.00 28.73  ? 65  GLN C CG  1 
ATOM   7410  C  CD  . GLN C 1 65  ? -9.686  16.384  -54.030 1.00 27.33  ? 65  GLN C CD  1 
ATOM   7411  O  OE1 . GLN C 1 65  ? -10.071 15.805  -55.046 1.00 26.94  ? 65  GLN C OE1 1 
ATOM   7412  N  NE2 . GLN C 1 65  ? -9.477  15.750  -52.874 1.00 22.00  ? 65  GLN C NE2 1 
ATOM   7413  N  N   . GLY C 1 66  ? -6.416  21.353  -56.028 1.00 30.75  ? 66  GLY C N   1 
ATOM   7414  C  CA  . GLY C 1 66  ? -5.230  21.803  -56.745 1.00 31.05  ? 66  GLY C CA  1 
ATOM   7415  C  C   . GLY C 1 66  ? -5.291  21.822  -58.270 1.00 33.99  ? 66  GLY C C   1 
ATOM   7416  O  O   . GLY C 1 66  ? -4.302  22.233  -58.898 1.00 33.47  ? 66  GLY C O   1 
ATOM   7417  N  N   . GLN C 1 67  ? -6.393  21.394  -58.898 1.00 22.21  ? 67  GLN C N   1 
ATOM   7418  C  CA  . GLN C 1 67  ? -6.489  21.413  -60.355 1.00 27.61  ? 67  GLN C CA  1 
ATOM   7419  C  C   . GLN C 1 67  ? -7.775  22.097  -60.772 1.00 24.91  ? 67  GLN C C   1 
ATOM   7420  O  O   . GLN C 1 67  ? -8.728  22.165  -60.000 1.00 24.44  ? 67  GLN C O   1 
ATOM   7421  C  CB  . GLN C 1 67  ? -6.456  20.012  -60.967 1.00 20.57  ? 67  GLN C CB  1 
ATOM   7422  C  CG  . GLN C 1 67  ? -5.094  19.353  -60.910 1.00 28.23  ? 67  GLN C CG  1 
ATOM   7423  C  CD  . GLN C 1 67  ? -5.082  18.036  -61.660 1.00 29.17  ? 67  GLN C CD  1 
ATOM   7424  O  OE1 . GLN C 1 67  ? -5.401  17.990  -62.844 1.00 36.32  ? 67  GLN C OE1 1 
ATOM   7425  N  NE2 . GLN C 1 67  ? -4.712  16.967  -60.981 1.00 34.61  ? 67  GLN C NE2 1 
ATOM   7426  N  N   . GLN C 1 68  ? -7.801  22.583  -62.013 1.00 22.03  ? 68  GLN C N   1 
ATOM   7427  C  CA  . GLN C 1 68  ? -8.930  23.333  -62.547 1.00 20.59  ? 68  GLN C CA  1 
ATOM   7428  C  C   . GLN C 1 68  ? -9.604  22.552  -63.656 1.00 23.24  ? 68  GLN C C   1 
ATOM   7429  O  O   . GLN C 1 68  ? -8.932  21.979  -64.511 1.00 22.48  ? 68  GLN C O   1 
ATOM   7430  C  CB  . GLN C 1 68  ? -8.498  24.697  -63.097 1.00 27.95  ? 68  GLN C CB  1 
ATOM   7431  C  CG  . GLN C 1 68  ? -9.663  25.631  -63.455 1.00 26.80  ? 68  GLN C CG  1 
ATOM   7432  C  CD  . GLN C 1 68  ? -9.151  26.936  -64.030 1.00 28.84  ? 68  GLN C CD  1 
ATOM   7433  O  OE1 . GLN C 1 68  ? -8.575  26.953  -65.114 1.00 33.23  ? 68  GLN C OE1 1 
ATOM   7434  N  NE2 . GLN C 1 68  ? -9.316  28.022  -63.290 1.00 22.39  ? 68  GLN C NE2 1 
ATOM   7435  N  N   . TYR C 1 69  ? -10.936 22.555  -63.644 1.00 23.85  ? 69  TYR C N   1 
ATOM   7436  C  CA  . TYR C 1 69  ? -11.732 21.726  -64.525 1.00 22.75  ? 69  TYR C CA  1 
ATOM   7437  C  C   . TYR C 1 69  ? -12.882 22.530  -65.102 1.00 28.00  ? 69  TYR C C   1 
ATOM   7438  O  O   . TYR C 1 69  ? -13.400 23.459  -64.461 1.00 22.62  ? 69  TYR C O   1 
ATOM   7439  C  CB  . TYR C 1 69  ? -12.332 20.484  -63.781 1.00 23.94  ? 69  TYR C CB  1 
ATOM   7440  C  CG  . TYR C 1 69  ? -11.330 19.585  -63.114 1.00 22.93  ? 69  TYR C CG  1 
ATOM   7441  C  CD1 . TYR C 1 69  ? -10.695 18.551  -63.822 1.00 23.38  ? 69  TYR C CD1 1 
ATOM   7442  C  CD2 . TYR C 1 69  ? -11.006 19.761  -61.768 1.00 23.53  ? 69  TYR C CD2 1 
ATOM   7443  C  CE1 . TYR C 1 69  ? -9.757  17.724  -63.194 1.00 20.42  ? 69  TYR C CE1 1 
ATOM   7444  C  CE2 . TYR C 1 69  ? -10.084 18.934  -61.136 1.00 25.17  ? 69  TYR C CE2 1 
ATOM   7445  C  CZ  . TYR C 1 69  ? -9.470  17.913  -61.848 1.00 20.63  ? 69  TYR C CZ  1 
ATOM   7446  O  OH  . TYR C 1 69  ? -8.551  17.110  -61.199 1.00 22.71  ? 69  TYR C OH  1 
ATOM   7447  N  N   . THR C 1 70  ? -13.267 22.158  -66.329 1.00 23.30  ? 70  THR C N   1 
ATOM   7448  C  CA  . THR C 1 70  ? -14.574 22.491  -66.872 1.00 26.46  ? 70  THR C CA  1 
ATOM   7449  C  C   . THR C 1 70  ? -15.641 21.577  -66.283 1.00 25.86  ? 70  THR C C   1 
ATOM   7450  O  O   . THR C 1 70  ? -15.353 20.493  -65.766 1.00 23.16  ? 70  THR C O   1 
ATOM   7451  C  CB  . THR C 1 70  ? -14.602 22.357  -68.398 1.00 26.76  ? 70  THR C CB  1 
ATOM   7452  O  OG1 . THR C 1 70  ? -14.548 20.973  -68.753 1.00 29.94  ? 70  THR C OG1 1 
ATOM   7453  C  CG2 . THR C 1 70  ? -13.446 23.146  -69.076 1.00 21.65  ? 70  THR C CG2 1 
ATOM   7454  N  N   . LEU C 1 71  ? -16.894 22.017  -66.387 1.00 25.03  ? 71  LEU C N   1 
ATOM   7455  C  CA  . LEU C 1 71  ? -17.979 21.194  -65.878 1.00 26.86  ? 71  LEU C CA  1 
ATOM   7456  C  C   . LEU C 1 71  ? -18.009 19.842  -66.576 1.00 29.96  ? 71  LEU C C   1 
ATOM   7457  O  O   . LEU C 1 71  ? -18.223 18.806  -65.935 1.00 25.98  ? 71  LEU C O   1 
ATOM   7458  C  CB  . LEU C 1 71  ? -19.313 21.901  -66.051 1.00 28.46  ? 71  LEU C CB  1 
ATOM   7459  C  CG  . LEU C 1 71  ? -20.481 21.059  -65.540 1.00 31.09  ? 71  LEU C CG  1 
ATOM   7460  C  CD1 . LEU C 1 71  ? -20.223 20.683  -64.089 1.00 30.74  ? 71  LEU C CD1 1 
ATOM   7461  C  CD2 . LEU C 1 71  ? -21.816 21.783  -65.719 1.00 27.91  ? 71  LEU C CD2 1 
ATOM   7462  N  N   . ALA C 1 72  ? -17.798 19.832  -67.892 1.00 30.34  ? 72  ALA C N   1 
ATOM   7463  C  CA  . ALA C 1 72  ? -17.817 18.569  -68.613 1.00 29.28  ? 72  ALA C CA  1 
ATOM   7464  C  C   . ALA C 1 72  ? -16.716 17.657  -68.107 1.00 28.54  ? 72  ALA C C   1 
ATOM   7465  O  O   . ALA C 1 72  ? -16.897 16.437  -68.013 1.00 38.16  ? 72  ALA C O   1 
ATOM   7466  C  CB  . ALA C 1 72  ? -17.667 18.813  -70.113 1.00 33.38  ? 72  ALA C CB  1 
ATOM   7467  N  N   . GLU C 1 73  ? -15.570 18.233  -67.756 1.00 27.25  ? 73  GLU C N   1 
ATOM   7468  C  CA  . GLU C 1 73  ? -14.497 17.421  -67.203 1.00 29.66  ? 73  GLU C CA  1 
ATOM   7469  C  C   . GLU C 1 73  ? -14.915 16.797  -65.877 1.00 32.88  ? 73  GLU C C   1 
ATOM   7470  O  O   . GLU C 1 73  ? -14.808 15.578  -65.699 1.00 28.89  ? 73  GLU C O   1 
ATOM   7471  C  CB  . GLU C 1 73  ? -13.238 18.266  -67.046 1.00 24.71  ? 73  GLU C CB  1 
ATOM   7472  C  CG  . GLU C 1 73  ? -12.517 18.403  -68.338 1.00 24.80  ? 73  GLU C CG  1 
ATOM   7473  C  CD  . GLU C 1 73  ? -11.479 19.466  -68.298 1.00 31.15  ? 73  GLU C CD  1 
ATOM   7474  O  OE1 . GLU C 1 73  ? -11.591 20.364  -67.445 1.00 30.97  ? 73  GLU C OE1 1 
ATOM   7475  O  OE2 . GLU C 1 73  ? -10.568 19.415  -69.139 1.00 30.78  ? 73  GLU C OE2 1 
ATOM   7476  N  N   . LEU C 1 74  ? -15.418 17.621  -64.944 1.00 26.74  ? 74  LEU C N   1 
ATOM   7477  C  CA  . LEU C 1 74  ? -15.909 17.108  -63.665 1.00 24.14  ? 74  LEU C CA  1 
ATOM   7478  C  C   . LEU C 1 74  ? -16.841 15.922  -63.861 1.00 30.35  ? 74  LEU C C   1 
ATOM   7479  O  O   . LEU C 1 74  ? -16.709 14.903  -63.177 1.00 27.25  ? 74  LEU C O   1 
ATOM   7480  C  CB  . LEU C 1 74  ? -16.626 18.211  -62.884 1.00 29.25  ? 74  LEU C CB  1 
ATOM   7481  C  CG  . LEU C 1 74  ? -15.746 19.362  -62.397 1.00 29.47  ? 74  LEU C CG  1 
ATOM   7482  C  CD1 . LEU C 1 74  ? -16.506 20.297  -61.444 1.00 27.52  ? 74  LEU C CD1 1 
ATOM   7483  C  CD2 . LEU C 1 74  ? -14.516 18.800  -61.725 1.00 26.85  ? 74  LEU C CD2 1 
ATOM   7484  N  N   . TRP C 1 75  ? -17.744 16.016  -64.842 1.00 28.87  ? 75  TRP C N   1 
ATOM   7485  C  CA  . TRP C 1 75  ? -18.701 14.950  -65.109 1.00 29.32  ? 75  TRP C CA  1 
ATOM   7486  C  C   . TRP C 1 75  ? -18.036 13.628  -65.495 1.00 30.73  ? 75  TRP C C   1 
ATOM   7487  O  O   . TRP C 1 75  ? -18.559 12.562  -65.158 1.00 32.74  ? 75  TRP C O   1 
ATOM   7488  C  CB  . TRP C 1 75  ? -19.656 15.390  -66.215 1.00 35.23  ? 75  TRP C CB  1 
ATOM   7489  C  CG  . TRP C 1 75  ? -20.739 16.291  -65.720 1.00 31.61  ? 75  TRP C CG  1 
ATOM   7490  C  CD1 . TRP C 1 75  ? -21.120 16.474  -64.420 1.00 30.79  ? 75  TRP C CD1 1 
ATOM   7491  C  CD2 . TRP C 1 75  ? -21.574 17.142  -66.507 1.00 33.64  ? 75  TRP C CD2 1 
ATOM   7492  N  NE1 . TRP C 1 75  ? -22.134 17.383  -64.353 1.00 31.74  ? 75  TRP C NE1 1 
ATOM   7493  C  CE2 . TRP C 1 75  ? -22.440 17.804  -65.622 1.00 32.82  ? 75  TRP C CE2 1 
ATOM   7494  C  CE3 . TRP C 1 75  ? -21.675 17.409  -67.877 1.00 31.89  ? 75  TRP C CE3 1 
ATOM   7495  C  CZ2 . TRP C 1 75  ? -23.405 18.717  -66.064 1.00 38.00  ? 75  TRP C CZ2 1 
ATOM   7496  C  CZ3 . TRP C 1 75  ? -22.624 18.308  -68.307 1.00 31.24  ? 75  TRP C CZ3 1 
ATOM   7497  C  CH2 . TRP C 1 75  ? -23.469 18.961  -67.408 1.00 36.72  ? 75  TRP C CH2 1 
ATOM   7498  N  N   . ASP C 1 76  ? -16.912 13.657  -66.214 1.00 33.51  ? 76  ASP C N   1 
ATOM   7499  C  CA  . ASP C 1 76  ? -16.239 12.411  -66.575 1.00 41.02  ? 76  ASP C CA  1 
ATOM   7500  C  C   . ASP C 1 76  ? -15.124 12.030  -65.611 1.00 36.24  ? 76  ASP C C   1 
ATOM   7501  O  O   . ASP C 1 76  ? -14.615 10.906  -65.699 1.00 38.69  ? 76  ASP C O   1 
ATOM   7502  C  CB  . ASP C 1 76  ? -15.639 12.466  -67.994 1.00 42.89  ? 76  ASP C CB  1 
ATOM   7503  C  CG  . ASP C 1 76  ? -16.612 12.983  -69.039 1.00 49.76  ? 76  ASP C CG  1 
ATOM   7504  O  OD1 . ASP C 1 76  ? -17.612 12.285  -69.317 1.00 50.18  ? 76  ASP C OD1 1 
ATOM   7505  O  OD2 . ASP C 1 76  ? -16.350 14.080  -69.604 1.00 49.20  ? 76  ASP C OD2 1 
ATOM   7506  N  N   . GLY C 1 77  ? -14.726 12.931  -64.710 1.00 32.77  ? 77  GLY C N   1 
ATOM   7507  C  CA  . GLY C 1 77  ? -13.634 12.637  -63.810 1.00 33.47  ? 77  GLY C CA  1 
ATOM   7508  C  C   . GLY C 1 77  ? -13.985 11.553  -62.804 1.00 30.84  ? 77  GLY C C   1 
ATOM   7509  O  O   . GLY C 1 77  ? -15.147 11.295  -62.504 1.00 33.13  ? 77  GLY C O   1 
ATOM   7510  N  N   . ASP C 1 78  ? -12.945 10.907  -62.278 1.00 29.78  ? 78  ASP C N   1 
ATOM   7511  C  CA  . ASP C 1 78  ? -13.060 9.915   -61.212 1.00 33.35  ? 78  ASP C CA  1 
ATOM   7512  C  C   . ASP C 1 78  ? -12.087 10.306  -60.113 1.00 34.29  ? 78  ASP C C   1 
ATOM   7513  O  O   . ASP C 1 78  ? -10.946 10.682  -60.402 1.00 32.24  ? 78  ASP C O   1 
ATOM   7514  C  CB  . ASP C 1 78  ? -12.717 8.491   -61.703 1.00 38.83  ? 78  ASP C CB  1 
ATOM   7515  C  CG  . ASP C 1 78  ? -13.946 7.642   -62.031 1.00 50.54  ? 78  ASP C CG  1 
ATOM   7516  O  OD1 . ASP C 1 78  ? -14.693 7.294   -61.084 1.00 45.65  ? 78  ASP C OD1 1 
ATOM   7517  O  OD2 . ASP C 1 78  ? -14.123 7.270   -63.227 1.00 48.23  ? 78  ASP C OD2 1 
ATOM   7518  N  N   . GLY C 1 79  ? -12.532 10.225  -58.857 1.00 32.79  ? 79  GLY C N   1 
ATOM   7519  C  CA  . GLY C 1 79  ? -11.642 10.410  -57.729 1.00 31.22  ? 79  GLY C CA  1 
ATOM   7520  C  C   . GLY C 1 79  ? -11.416 11.842  -57.299 1.00 26.48  ? 79  GLY C C   1 
ATOM   7521  O  O   . GLY C 1 79  ? -10.818 12.070  -56.243 1.00 29.32  ? 79  GLY C O   1 
ATOM   7522  N  N   . VAL C 1 80  ? -11.858 12.803  -58.072 1.00 28.66  ? 80  VAL C N   1 
ATOM   7523  C  CA  . VAL C 1 80  ? -11.777 14.200  -57.672 1.00 29.31  ? 80  VAL C CA  1 
ATOM   7524  C  C   . VAL C 1 80  ? -12.972 14.531  -56.792 1.00 25.27  ? 80  VAL C C   1 
ATOM   7525  O  O   . VAL C 1 80  ? -14.102 14.096  -57.056 1.00 28.62  ? 80  VAL C O   1 
ATOM   7526  C  CB  . VAL C 1 80  ? -11.721 15.111  -58.918 1.00 26.46  ? 80  VAL C CB  1 
ATOM   7527  C  CG1 . VAL C 1 80  ? -11.659 16.575  -58.511 1.00 25.53  ? 80  VAL C CG1 1 
ATOM   7528  C  CG2 . VAL C 1 80  ? -10.544 14.708  -59.803 1.00 27.12  ? 80  VAL C CG2 1 
ATOM   7529  N  N   . ARG C 1 81  ? -12.732 15.332  -55.761 1.00 22.96  ? 81  ARG C N   1 
ATOM   7530  C  CA  . ARG C 1 81  ? -13.739 15.634  -54.763 1.00 29.96  ? 81  ARG C CA  1 
ATOM   7531  C  C   . ARG C 1 81  ? -13.860 17.129  -54.529 1.00 24.56  ? 81  ARG C C   1 
ATOM   7532  O  O   . ARG C 1 81  ? -12.901 17.890  -54.685 1.00 26.98  ? 81  ARG C O   1 
ATOM   7533  C  CB  . ARG C 1 81  ? -13.411 14.957  -53.420 1.00 28.06  ? 81  ARG C CB  1 
ATOM   7534  C  CG  . ARG C 1 81  ? -13.491 13.438  -53.457 1.00 27.80  ? 81  ARG C CG  1 
ATOM   7535  C  CD  . ARG C 1 81  ? -13.461 12.860  -52.047 1.00 25.56  ? 81  ARG C CD  1 
ATOM   7536  N  NE  . ARG C 1 81  ? -14.808 12.731  -51.478 1.00 31.98  ? 81  ARG C NE  1 
ATOM   7537  C  CZ  . ARG C 1 81  ? -15.310 13.586  -50.599 1.00 32.03  ? 81  ARG C CZ  1 
ATOM   7538  N  NH1 . ARG C 1 81  ? -14.639 14.662  -50.224 1.00 31.64  ? 81  ARG C NH1 1 
ATOM   7539  N  NH2 . ARG C 1 81  ? -16.503 13.351  -50.069 1.00 32.27  ? 81  ARG C NH2 1 
ATOM   7540  N  N   . TRP C 1 82  ? -15.045 17.535  -54.108 1.00 22.81  ? 82  TRP C N   1 
ATOM   7541  C  CA  . TRP C 1 82  ? -15.175 18.809  -53.412 1.00 27.93  ? 82  TRP C CA  1 
ATOM   7542  C  C   . TRP C 1 82  ? -15.168 18.498  -51.921 1.00 30.50  ? 82  TRP C C   1 
ATOM   7543  O  O   . TRP C 1 82  ? -16.173 17.986  -51.400 1.00 29.86  ? 82  TRP C O   1 
ATOM   7544  C  CB  . TRP C 1 82  ? -16.470 19.515  -53.813 1.00 28.13  ? 82  TRP C CB  1 
ATOM   7545  C  CG  . TRP C 1 82  ? -16.654 20.849  -53.218 1.00 26.79  ? 82  TRP C CG  1 
ATOM   7546  C  CD1 . TRP C 1 82  ? -15.861 21.464  -52.300 1.00 27.67  ? 82  TRP C CD1 1 
ATOM   7547  C  CD2 . TRP C 1 82  ? -17.718 21.753  -53.505 1.00 26.91  ? 82  TRP C CD2 1 
ATOM   7548  N  NE1 . TRP C 1 82  ? -16.372 22.700  -51.982 1.00 26.04  ? 82  TRP C NE1 1 
ATOM   7549  C  CE2 . TRP C 1 82  ? -17.518 22.899  -52.707 1.00 26.75  ? 82  TRP C CE2 1 
ATOM   7550  C  CE3 . TRP C 1 82  ? -18.828 21.699  -54.344 1.00 27.37  ? 82  TRP C CE3 1 
ATOM   7551  C  CZ2 . TRP C 1 82  ? -18.376 23.984  -52.742 1.00 25.15  ? 82  TRP C CZ2 1 
ATOM   7552  C  CZ3 . TRP C 1 82  ? -19.684 22.790  -54.386 1.00 25.96  ? 82  TRP C CZ3 1 
ATOM   7553  C  CH2 . TRP C 1 82  ? -19.454 23.910  -53.589 1.00 27.72  ? 82  TRP C CH2 1 
ATOM   7554  N  N   . PRO C 1 83  ? -14.060 18.705  -51.214 1.00 24.75  ? 83  PRO C N   1 
ATOM   7555  C  CA  . PRO C 1 83  ? -14.018 18.351  -49.793 1.00 29.65  ? 83  PRO C CA  1 
ATOM   7556  C  C   . PRO C 1 83  ? -14.716 19.419  -48.971 1.00 29.75  ? 83  PRO C C   1 
ATOM   7557  O  O   . PRO C 1 83  ? -14.650 20.609  -49.293 1.00 27.97  ? 83  PRO C O   1 
ATOM   7558  C  CB  . PRO C 1 83  ? -12.512 18.301  -49.479 1.00 26.84  ? 83  PRO C CB  1 
ATOM   7559  C  CG  . PRO C 1 83  ? -11.842 18.235  -50.840 1.00 25.53  ? 83  PRO C CG  1 
ATOM   7560  C  CD  . PRO C 1 83  ? -12.728 19.074  -51.705 1.00 27.22  ? 83  PRO C CD  1 
ATOM   7561  N  N   . LEU C 1 84  ? -15.379 18.970  -47.895 1.00 26.41  ? 84  LEU C N   1 
ATOM   7562  C  CA  . LEU C 1 84  ? -16.130 19.864  -47.020 1.00 28.41  ? 84  LEU C CA  1 
ATOM   7563  C  C   . LEU C 1 84  ? -15.267 20.965  -46.432 1.00 31.21  ? 84  LEU C C   1 
ATOM   7564  O  O   . LEU C 1 84  ? -15.762 22.079  -46.204 1.00 31.21  ? 84  LEU C O   1 
ATOM   7565  C  CB  . LEU C 1 84  ? -16.772 19.080  -45.873 1.00 27.47  ? 84  LEU C CB  1 
ATOM   7566  C  CG  . LEU C 1 84  ? -17.787 19.882  -45.058 1.00 29.36  ? 84  LEU C CG  1 
ATOM   7567  C  CD1 . LEU C 1 84  ? -19.128 19.975  -45.799 1.00 26.87  ? 84  LEU C CD1 1 
ATOM   7568  C  CD2 . LEU C 1 84  ? -17.971 19.283  -43.653 1.00 27.06  ? 84  LEU C CD2 1 
ATOM   7569  N  N   . GLU C 1 85  ? -13.999 20.667  -46.144 1.00 24.61  ? 85  GLU C N   1 
ATOM   7570  C  CA  . GLU C 1 85  ? -13.100 21.639  -45.559 1.00 26.85  ? 85  GLU C CA  1 
ATOM   7571  C  C   . GLU C 1 85  ? -12.559 22.630  -46.584 1.00 28.13  ? 85  GLU C C   1 
ATOM   7572  O  O   . GLU C 1 85  ? -11.888 23.587  -46.185 1.00 26.25  ? 85  GLU C O   1 
ATOM   7573  C  CB  . GLU C 1 85  ? -11.945 20.927  -44.859 1.00 21.74  ? 85  GLU C CB  1 
ATOM   7574  C  CG  . GLU C 1 85  ? -10.995 20.198  -45.784 1.00 26.57  ? 85  GLU C CG  1 
ATOM   7575  C  CD  . GLU C 1 85  ? -11.381 18.747  -46.051 1.00 26.44  ? 85  GLU C CD  1 
ATOM   7576  O  OE1 . GLU C 1 85  ? -12.581 18.395  -45.952 1.00 26.18  ? 85  GLU C OE1 1 
ATOM   7577  O  OE2 . GLU C 1 85  ? -10.479 17.950  -46.392 1.00 27.62  ? 85  GLU C OE2 1 
ATOM   7578  N  N   . ASP C 1 86  ? -12.813 22.425  -47.878 1.00 24.04  ? 86  ASP C N   1 
ATOM   7579  C  CA  . ASP C 1 86  ? -12.284 23.307  -48.917 1.00 25.02  ? 86  ASP C CA  1 
ATOM   7580  C  C   . ASP C 1 86  ? -13.408 24.152  -49.504 1.00 23.76  ? 86  ASP C C   1 
ATOM   7581  O  O   . ASP C 1 86  ? -14.487 23.646  -49.795 1.00 28.89  ? 86  ASP C O   1 
ATOM   7582  C  CB  . ASP C 1 86  ? -11.631 22.534  -50.075 1.00 27.21  ? 86  ASP C CB  1 
ATOM   7583  C  CG  . ASP C 1 86  ? -10.358 21.804  -49.688 1.00 26.36  ? 86  ASP C CG  1 
ATOM   7584  O  OD1 . ASP C 1 86  ? -9.780  22.059  -48.608 1.00 23.72  ? 86  ASP C OD1 1 
ATOM   7585  O  OD2 . ASP C 1 86  ? -9.920  20.970  -50.513 1.00 27.68  ? 86  ASP C OD2 1 
ATOM   7586  N  N   . ALA C 1 87  ? -13.150 25.432  -49.731 1.00 31.52  ? 87  ALA C N   1 
ATOM   7587  C  CA  . ALA C 1 87  ? -14.055 26.193  -50.580 1.00 27.83  ? 87  ALA C CA  1 
ATOM   7588  C  C   . ALA C 1 87  ? -13.774 25.845  -52.035 1.00 23.69  ? 87  ALA C C   1 
ATOM   7589  O  O   . ALA C 1 87  ? -12.612 25.785  -52.452 1.00 27.81  ? 87  ALA C O   1 
ATOM   7590  C  CB  . ALA C 1 87  ? -13.890 27.691  -50.349 1.00 25.70  ? 87  ALA C CB  1 
ATOM   7591  N  N   . ALA C 1 88  ? -14.825 25.605  -52.811 1.00 23.42  ? 88  ALA C N   1 
ATOM   7592  C  CA  . ALA C 1 88  ? -14.626 25.538  -54.259 1.00 27.25  ? 88  ALA C CA  1 
ATOM   7593  C  C   . ALA C 1 88  ? -14.109 26.881  -54.765 1.00 25.67  ? 88  ALA C C   1 
ATOM   7594  O  O   . ALA C 1 88  ? -14.549 27.935  -54.309 1.00 32.09  ? 88  ALA C O   1 
ATOM   7595  C  CB  . ALA C 1 88  ? -15.927 25.177  -54.970 1.00 28.19  ? 88  ALA C CB  1 
ATOM   7596  N  N   . ILE C 1 89  ? -13.147 26.859  -55.684 1.00 27.20  ? 89  ILE C N   1 
ATOM   7597  C  CA  . ILE C 1 89  ? -12.647 28.097  -56.287 1.00 19.74  ? 89  ILE C CA  1 
ATOM   7598  C  C   . ILE C 1 89  ? -13.270 28.197  -57.683 1.00 22.72  ? 89  ILE C C   1 
ATOM   7599  O  O   . ILE C 1 89  ? -12.977 27.386  -58.570 1.00 22.48  ? 89  ILE C O   1 
ATOM   7600  C  CB  . ILE C 1 89  ? -11.112 28.145  -56.317 1.00 22.57  ? 89  ILE C CB  1 
ATOM   7601  C  CG1 . ILE C 1 89  ? -10.517 27.854  -54.939 1.00 21.07  ? 89  ILE C CG1 1 
ATOM   7602  C  CG2 . ILE C 1 89  ? -10.602 29.518  -56.771 1.00 25.29  ? 89  ILE C CG2 1 
ATOM   7603  C  CD1 . ILE C 1 89  ? -9.019  27.775  -54.945 1.00 22.59  ? 89  ILE C CD1 1 
ATOM   7604  N  N   . ILE C 1 90  ? -14.193 29.138  -57.856 1.00 23.70  ? 90  ILE C N   1 
ATOM   7605  C  CA  . ILE C 1 90  ? -14.963 29.282  -59.087 1.00 27.72  ? 90  ILE C CA  1 
ATOM   7606  C  C   . ILE C 1 90  ? -14.314 30.365  -59.929 1.00 28.51  ? 90  ILE C C   1 
ATOM   7607  O  O   . ILE C 1 90  ? -14.065 31.474  -59.436 1.00 29.84  ? 90  ILE C O   1 
ATOM   7608  C  CB  . ILE C 1 90  ? -16.436 29.628  -58.798 1.00 27.59  ? 90  ILE C CB  1 
ATOM   7609  C  CG1 . ILE C 1 90  ? -17.033 28.605  -57.832 1.00 26.81  ? 90  ILE C CG1 1 
ATOM   7610  C  CG2 . ILE C 1 90  ? -17.263 29.645  -60.092 1.00 24.49  ? 90  ILE C CG2 1 
ATOM   7611  C  CD1 . ILE C 1 90  ? -16.996 27.217  -58.386 1.00 24.50  ? 90  ILE C CD1 1 
ATOM   7612  N  N   . PHE C 1 91  ? -14.036 30.051  -61.194 1.00 26.97  ? 91  PHE C N   1 
ATOM   7613  C  CA  . PHE C 1 91  ? -13.451 31.010  -62.125 1.00 23.90  ? 91  PHE C CA  1 
ATOM   7614  C  C   . PHE C 1 91  ? -14.436 31.310  -63.246 1.00 24.46  ? 91  PHE C C   1 
ATOM   7615  O  O   . PHE C 1 91  ? -14.931 30.390  -63.902 1.00 29.31  ? 91  PHE C O   1 
ATOM   7616  C  CB  . PHE C 1 91  ? -12.151 30.489  -62.721 1.00 23.95  ? 91  PHE C CB  1 
ATOM   7617  C  CG  . PHE C 1 91  ? -11.627 31.342  -63.838 1.00 27.10  ? 91  PHE C CG  1 
ATOM   7618  C  CD1 . PHE C 1 91  ? -10.951 32.504  -63.563 1.00 23.01  ? 91  PHE C CD1 1 
ATOM   7619  C  CD2 . PHE C 1 91  ? -11.818 30.976  -65.164 1.00 24.92  ? 91  PHE C CD2 1 
ATOM   7620  C  CE1 . PHE C 1 91  ? -10.474 33.297  -64.584 1.00 26.54  ? 91  PHE C CE1 1 
ATOM   7621  C  CE2 . PHE C 1 91  ? -11.340 31.763  -66.183 1.00 28.21  ? 91  PHE C CE2 1 
ATOM   7622  C  CZ  . PHE C 1 91  ? -10.669 32.924  -65.892 1.00 28.99  ? 91  PHE C CZ  1 
ATOM   7623  N  N   . VAL C 1 92  ? -14.712 32.589  -63.471 1.00 26.97  ? 92  VAL C N   1 
ATOM   7624  C  CA  . VAL C 1 92  ? -15.604 33.039  -64.535 1.00 26.15  ? 92  VAL C CA  1 
ATOM   7625  C  C   . VAL C 1 92  ? -14.760 33.742  -65.599 1.00 25.30  ? 92  VAL C C   1 
ATOM   7626  O  O   . VAL C 1 92  ? -14.164 34.789  -65.316 1.00 27.78  ? 92  VAL C O   1 
ATOM   7627  C  CB  . VAL C 1 92  ? -16.690 33.968  -63.986 1.00 26.98  ? 92  VAL C CB  1 
ATOM   7628  C  CG1 . VAL C 1 92  ? -17.662 34.380  -65.081 1.00 32.23  ? 92  VAL C CG1 1 
ATOM   7629  C  CG2 . VAL C 1 92  ? -17.425 33.287  -62.884 1.00 25.72  ? 92  VAL C CG2 1 
ATOM   7630  N  N   . PRO C 1 93  ? -14.648 33.204  -66.812 1.00 22.82  ? 93  PRO C N   1 
ATOM   7631  C  CA  . PRO C 1 93  ? -13.926 33.924  -67.876 1.00 26.69  ? 93  PRO C CA  1 
ATOM   7632  C  C   . PRO C 1 93  ? -14.653 35.213  -68.236 1.00 30.15  ? 93  PRO C C   1 
ATOM   7633  O  O   . PRO C 1 93  ? -15.857 35.213  -68.504 1.00 32.22  ? 93  PRO C O   1 
ATOM   7634  C  CB  . PRO C 1 93  ? -13.917 32.935  -69.054 1.00 25.77  ? 93  PRO C CB  1 
ATOM   7635  C  CG  . PRO C 1 93  ? -14.326 31.618  -68.471 1.00 33.88  ? 93  PRO C CG  1 
ATOM   7636  C  CD  . PRO C 1 93  ? -15.219 31.941  -67.292 1.00 30.97  ? 93  PRO C CD  1 
ATOM   7637  N  N   . LEU C 1 94  ? -13.905 36.311  -68.235 1.00 31.96  ? 94  LEU C N   1 
ATOM   7638  C  CA  . LEU C 1 94  ? -14.370 37.671  -68.487 1.00 32.20  ? 94  LEU C CA  1 
ATOM   7639  C  C   . LEU C 1 94  ? -13.153 38.555  -68.693 1.00 32.63  ? 94  LEU C C   1 
ATOM   7640  O  O   . LEU C 1 94  ? -12.610 39.106  -67.724 1.00 36.19  ? 94  LEU C O   1 
ATOM   7641  C  CB  . LEU C 1 94  ? -15.207 38.202  -67.327 1.00 33.57  ? 94  LEU C CB  1 
ATOM   7642  C  CG  . LEU C 1 94  ? -15.590 39.684  -67.349 1.00 39.71  ? 94  LEU C CG  1 
ATOM   7643  C  CD1 . LEU C 1 94  ? -16.645 39.934  -68.416 1.00 38.95  ? 94  LEU C CD1 1 
ATOM   7644  C  CD2 . LEU C 1 94  ? -16.081 40.146  -65.960 1.00 35.74  ? 94  LEU C CD2 1 
ATOM   7645  N  N   . PRO C 1 95  ? -12.692 38.710  -69.930 1.00 35.05  ? 95  PRO C N   1 
ATOM   7646  C  CA  . PRO C 1 95  ? -11.451 39.466  -70.166 1.00 35.41  ? 95  PRO C CA  1 
ATOM   7647  C  C   . PRO C 1 95  ? -11.534 40.889  -69.617 1.00 30.88  ? 95  PRO C C   1 
ATOM   7648  O  O   . PRO C 1 95  ? -12.576 41.543  -69.659 1.00 34.29  ? 95  PRO C O   1 
ATOM   7649  C  CB  . PRO C 1 95  ? -11.305 39.440  -71.697 1.00 37.48  ? 95  PRO C CB  1 
ATOM   7650  C  CG  . PRO C 1 95  ? -12.115 38.244  -72.143 1.00 32.75  ? 95  PRO C CG  1 
ATOM   7651  C  CD  . PRO C 1 95  ? -13.269 38.156  -71.170 1.00 30.10  ? 95  PRO C CD  1 
ATOM   7652  N  N   . GLY C 1 96  ? -10.430 41.345  -69.042 1.00 32.34  ? 96  GLY C N   1 
ATOM   7653  C  CA  . GLY C 1 96  ? -10.380 42.617  -68.373 1.00 31.62  ? 96  GLY C CA  1 
ATOM   7654  C  C   . GLY C 1 96  ? -10.899 42.583  -66.951 1.00 34.06  ? 96  GLY C C   1 
ATOM   7655  O  O   . GLY C 1 96  ? -10.544 43.452  -66.152 1.00 37.03  ? 96  GLY C O   1 
ATOM   7656  N  N   . GLY C 1 97  ? -11.732 41.599  -66.625 1.00 36.79  ? 97  GLY C N   1 
ATOM   7657  C  CA  . GLY C 1 97  ? -12.158 41.376  -65.262 1.00 37.80  ? 97  GLY C CA  1 
ATOM   7658  C  C   . GLY C 1 97  ? -13.297 42.278  -64.831 1.00 38.08  ? 97  GLY C C   1 
ATOM   7659  O  O   . GLY C 1 97  ? -14.070 42.827  -65.636 1.00 32.99  ? 97  GLY C O   1 
ATOM   7660  N  N   . LEU C 1 98  ? -13.402 42.411  -63.527 1.00 32.39  ? 98  LEU C N   1 
ATOM   7661  C  CA  . LEU C 1 98  ? -14.332 43.230  -62.784 1.00 27.49  ? 98  LEU C CA  1 
ATOM   7662  C  C   . LEU C 1 98  ? -13.661 44.522  -62.362 1.00 27.79  ? 98  LEU C C   1 
ATOM   7663  O  O   . LEU C 1 98  ? -12.448 44.550  -62.140 1.00 31.08  ? 98  LEU C O   1 
ATOM   7664  C  CB  . LEU C 1 98  ? -14.821 42.488  -61.537 1.00 31.24  ? 98  LEU C CB  1 
ATOM   7665  C  CG  . LEU C 1 98  ? -15.777 41.365  -61.866 1.00 28.49  ? 98  LEU C CG  1 
ATOM   7666  C  CD1 . LEU C 1 98  ? -16.136 40.557  -60.622 1.00 29.22  ? 98  LEU C CD1 1 
ATOM   7667  C  CD2 . LEU C 1 98  ? -17.010 41.943  -62.541 1.00 29.42  ? 98  LEU C CD2 1 
ATOM   7668  N  N   . PRO C 1 99  ? -14.427 45.605  -62.252 1.00 33.28  ? 99  PRO C N   1 
ATOM   7669  C  CA  . PRO C 1 99  ? -13.887 46.842  -61.682 1.00 30.08  ? 99  PRO C CA  1 
ATOM   7670  C  C   . PRO C 1 99  ? -13.917 46.792  -60.165 1.00 31.38  ? 99  PRO C C   1 
ATOM   7671  O  O   . PRO C 1 99  ? -14.730 46.091  -59.558 1.00 30.09  ? 99  PRO C O   1 
ATOM   7672  C  CB  . PRO C 1 99  ? -14.850 47.907  -62.205 1.00 32.75  ? 99  PRO C CB  1 
ATOM   7673  C  CG  . PRO C 1 99  ? -16.149 47.185  -62.207 1.00 30.87  ? 99  PRO C CG  1 
ATOM   7674  C  CD  . PRO C 1 99  ? -15.841 45.761  -62.634 1.00 29.47  ? 99  PRO C CD  1 
ATOM   7675  N  N   . ASP C 1 100 ? -13.017 47.558  -59.557 1.00 31.79  ? 100 ASP C N   1 
ATOM   7676  C  CA  . ASP C 1 100 ? -12.958 47.633  -58.107 1.00 27.33  ? 100 ASP C CA  1 
ATOM   7677  C  C   . ASP C 1 100 ? -14.334 47.940  -57.546 1.00 34.22  ? 100 ASP C C   1 
ATOM   7678  O  O   . ASP C 1 100 ? -15.143 48.621  -58.181 1.00 31.06  ? 100 ASP C O   1 
ATOM   7679  C  CB  . ASP C 1 100 ? -11.980 48.712  -57.678 1.00 31.69  ? 100 ASP C CB  1 
ATOM   7680  C  CG  . ASP C 1 100 ? -10.656 48.153  -57.284 1.00 35.96  ? 100 ASP C CG  1 
ATOM   7681  O  OD1 . ASP C 1 100 ? -10.607 46.950  -56.933 1.00 31.06  ? 100 ASP C OD1 1 
ATOM   7682  O  OD2 . ASP C 1 100 ? -9.663  48.918  -57.338 1.00 32.08  ? 100 ASP C OD2 1 
ATOM   7683  N  N   . GLY C 1 101 ? -14.615 47.402  -56.362 1.00 32.61  ? 101 GLY C N   1 
ATOM   7684  C  CA  . GLY C 1 101 ? -15.784 47.824  -55.633 1.00 29.90  ? 101 GLY C CA  1 
ATOM   7685  C  C   . GLY C 1 101 ? -16.537 46.639  -55.099 1.00 31.56  ? 101 GLY C C   1 
ATOM   7686  O  O   . GLY C 1 101 ? -16.007 45.527  -55.045 1.00 28.52  ? 101 GLY C O   1 
ATOM   7687  N  N   . VAL C 1 102 ? -17.787 46.901  -54.716 1.00 30.52  ? 102 VAL C N   1 
ATOM   7688  C  CA  . VAL C 1 102 ? -18.687 45.926  -54.106 1.00 30.01  ? 102 VAL C CA  1 
ATOM   7689  C  C   . VAL C 1 102 ? -19.673 45.495  -55.172 1.00 33.51  ? 102 VAL C C   1 
ATOM   7690  O  O   . VAL C 1 102 ? -20.323 46.340  -55.794 1.00 34.03  ? 102 VAL C O   1 
ATOM   7691  C  CB  . VAL C 1 102 ? -19.428 46.531  -52.898 1.00 27.79  ? 102 VAL C CB  1 
ATOM   7692  C  CG1 . VAL C 1 102 ? -20.146 45.448  -52.085 1.00 33.82  ? 102 VAL C CG1 1 
ATOM   7693  C  CG2 . VAL C 1 102 ? -18.468 47.319  -52.019 1.00 29.18  ? 102 VAL C CG2 1 
ATOM   7694  N  N   . HIS C 1 103 ? -19.781 44.193  -55.398 1.00 32.31  ? 103 HIS C N   1 
ATOM   7695  C  CA  . HIS C 1 103 ? -20.574 43.657  -56.494 1.00 34.27  ? 103 HIS C CA  1 
ATOM   7696  C  C   . HIS C 1 103 ? -21.631 42.723  -55.936 1.00 33.40  ? 103 HIS C C   1 
ATOM   7697  O  O   . HIS C 1 103 ? -21.338 41.895  -55.065 1.00 29.88  ? 103 HIS C O   1 
ATOM   7698  C  CB  . HIS C 1 103 ? -19.700 42.900  -57.502 1.00 32.43  ? 103 HIS C CB  1 
ATOM   7699  C  CG  . HIS C 1 103 ? -18.678 43.758  -58.186 1.00 34.41  ? 103 HIS C CG  1 
ATOM   7700  N  ND1 . HIS C 1 103 ? -19.001 44.641  -59.192 1.00 36.85  ? 103 HIS C ND1 1 
ATOM   7701  C  CD2 . HIS C 1 103 ? -17.337 43.860  -58.013 1.00 34.32  ? 103 HIS C CD2 1 
ATOM   7702  C  CE1 . HIS C 1 103 ? -17.903 45.254  -59.607 1.00 35.32  ? 103 HIS C CE1 1 
ATOM   7703  N  NE2 . HIS C 1 103 ? -16.881 44.805  -58.902 1.00 30.27  ? 103 HIS C NE2 1 
ATOM   7704  N  N   . GLU C 1 104 ? -22.848 42.846  -56.449 1.00 27.84  ? 104 GLU C N   1 
ATOM   7705  C  CA  . GLU C 1 104 ? -23.942 41.969  -56.035 1.00 34.75  ? 104 GLU C CA  1 
ATOM   7706  C  C   . GLU C 1 104 ? -23.841 40.657  -56.806 1.00 37.05  ? 104 GLU C C   1 
ATOM   7707  O  O   . GLU C 1 104 ? -24.350 40.516  -57.922 1.00 34.72  ? 104 GLU C O   1 
ATOM   7708  C  CB  . GLU C 1 104 ? -25.293 42.634  -56.247 1.00 33.86  ? 104 GLU C CB  1 
ATOM   7709  C  CG  . GLU C 1 104 ? -26.414 41.825  -55.622 1.00 42.93  ? 104 GLU C CG  1 
ATOM   7710  C  CD  . GLU C 1 104 ? -27.780 42.089  -56.239 1.00 53.74  ? 104 GLU C CD  1 
ATOM   7711  O  OE1 . GLU C 1 104 ? -28.093 41.478  -57.288 1.00 53.34  ? 104 GLU C OE1 1 
ATOM   7712  O  OE2 . GLU C 1 104 ? -28.550 42.887  -55.652 1.00 49.78  ? 104 GLU C OE2 1 
ATOM   7713  N  N   . LEU C 1 105 ? -23.184 39.674  -56.190 1.00 37.80  ? 105 LEU C N   1 
ATOM   7714  C  CA  . LEU C 1 105 ? -22.942 38.386  -56.823 1.00 34.36  ? 105 LEU C CA  1 
ATOM   7715  C  C   . LEU C 1 105 ? -24.107 37.446  -56.551 1.00 37.59  ? 105 LEU C C   1 
ATOM   7716  O  O   . LEU C 1 105 ? -24.490 37.231  -55.397 1.00 33.96  ? 105 LEU C O   1 
ATOM   7717  C  CB  . LEU C 1 105 ? -21.637 37.769  -56.320 1.00 30.69  ? 105 LEU C CB  1 
ATOM   7718  C  CG  . LEU C 1 105 ? -21.112 36.549  -57.097 1.00 34.48  ? 105 LEU C CG  1 
ATOM   7719  C  CD1 . LEU C 1 105 ? -20.940 36.867  -58.568 1.00 31.71  ? 105 LEU C CD1 1 
ATOM   7720  C  CD2 . LEU C 1 105 ? -19.790 36.049  -56.507 1.00 33.36  ? 105 LEU C CD2 1 
ATOM   7721  N  N   . SER C 1 106 ? -24.662 36.881  -57.616 1.00 32.96  ? 106 SER C N   1 
ATOM   7722  C  CA  . SER C 1 106 ? -25.731 35.907  -57.511 1.00 29.77  ? 106 SER C CA  1 
ATOM   7723  C  C   . SER C 1 106 ? -25.277 34.606  -58.157 1.00 33.14  ? 106 SER C C   1 
ATOM   7724  O  O   . SER C 1 106 ? -24.746 34.616  -59.270 1.00 29.50  ? 106 SER C O   1 
ATOM   7725  C  CB  . SER C 1 106 ? -27.007 36.429  -58.166 1.00 29.37  ? 106 SER C CB  1 
ATOM   7726  O  OG  . SER C 1 106 ? -27.624 37.408  -57.351 1.00 40.01  ? 106 SER C OG  1 
ATOM   7727  N  N   . ILE C 1 107 ? -25.465 33.492  -57.445 1.00 29.61  ? 107 ILE C N   1 
ATOM   7728  C  CA  . ILE C 1 107 ? -25.082 32.177  -57.935 1.00 32.72  ? 107 ILE C CA  1 
ATOM   7729  C  C   . ILE C 1 107 ? -26.301 31.268  -57.921 1.00 35.35  ? 107 ILE C C   1 
ATOM   7730  O  O   . ILE C 1 107 ? -27.215 31.431  -57.105 1.00 35.35  ? 107 ILE C O   1 
ATOM   7731  C  CB  . ILE C 1 107 ? -23.942 31.548  -57.102 1.00 33.86  ? 107 ILE C CB  1 
ATOM   7732  C  CG1 . ILE C 1 107 ? -24.386 31.343  -55.653 1.00 30.16  ? 107 ILE C CG1 1 
ATOM   7733  C  CG2 . ILE C 1 107 ? -22.709 32.429  -57.130 1.00 32.91  ? 107 ILE C CG2 1 
ATOM   7734  C  CD1 . ILE C 1 107 ? -24.870 29.960  -55.331 1.00 39.83  ? 107 ILE C CD1 1 
ATOM   7735  N  N   . GLU C 1 108 ? -26.300 30.290  -58.827 1.00 32.21  ? 108 GLU C N   1 
ATOM   7736  C  CA  . GLU C 1 108 ? -27.242 29.169  -58.790 1.00 35.98  ? 108 GLU C CA  1 
ATOM   7737  C  C   . GLU C 1 108 ? -26.395 27.903  -58.829 1.00 38.19  ? 108 GLU C C   1 
ATOM   7738  O  O   . GLU C 1 108 ? -25.921 27.507  -59.900 1.00 34.90  ? 108 GLU C O   1 
ATOM   7739  C  CB  . GLU C 1 108 ? -28.236 29.225  -59.950 1.00 44.67  ? 108 GLU C CB  1 
ATOM   7740  C  CG  . GLU C 1 108 ? -29.371 28.193  -59.889 1.00 47.34  ? 108 GLU C CG  1 
ATOM   7741  C  CD  . GLU C 1 108 ? -29.736 27.621  -61.268 1.00 59.23  ? 108 GLU C CD  1 
ATOM   7742  O  OE1 . GLU C 1 108 ? -29.625 28.358  -62.278 1.00 58.37  ? 108 GLU C OE1 1 
ATOM   7743  O  OE2 . GLU C 1 108 ? -30.146 26.435  -61.341 1.00 59.75  ? 108 GLU C OE2 1 
ATOM   7744  N  N   . LEU C 1 109 ? -26.172 27.297  -57.659 1.00 36.36  ? 109 LEU C N   1 
ATOM   7745  C  CA  . LEU C 1 109 ? -25.327 26.113  -57.528 1.00 36.31  ? 109 LEU C CA  1 
ATOM   7746  C  C   . LEU C 1 109 ? -26.165 24.851  -57.619 1.00 35.90  ? 109 LEU C C   1 
ATOM   7747  O  O   . LEU C 1 109 ? -27.253 24.779  -57.050 1.00 38.10  ? 109 LEU C O   1 
ATOM   7748  C  CB  . LEU C 1 109 ? -24.573 26.118  -56.197 1.00 36.63  ? 109 LEU C CB  1 
ATOM   7749  C  CG  . LEU C 1 109 ? -23.943 24.787  -55.772 1.00 33.04  ? 109 LEU C CG  1 
ATOM   7750  C  CD1 . LEU C 1 109 ? -22.868 24.358  -56.746 1.00 32.17  ? 109 LEU C CD1 1 
ATOM   7751  C  CD2 . LEU C 1 109 ? -23.366 24.897  -54.369 1.00 36.15  ? 109 LEU C CD2 1 
ATOM   7752  N  N   . ARG C 1 110 ? -25.647 23.847  -58.326 1.00 34.99  ? 110 ARG C N   1 
ATOM   7753  C  CA  . ARG C 1 110 ? -26.374 22.602  -58.524 1.00 32.73  ? 110 ARG C CA  1 
ATOM   7754  C  C   . ARG C 1 110 ? -25.499 21.422  -58.121 1.00 35.10  ? 110 ARG C C   1 
ATOM   7755  O  O   . ARG C 1 110 ? -24.322 21.374  -58.488 1.00 35.65  ? 110 ARG C O   1 
ATOM   7756  C  CB  . ARG C 1 110 ? -26.819 22.485  -59.981 1.00 41.31  ? 110 ARG C CB  1 
ATOM   7757  C  CG  . ARG C 1 110 ? -27.466 23.760  -60.504 1.00 41.41  ? 110 ARG C CG  1 
ATOM   7758  C  CD  . ARG C 1 110 ? -28.610 23.465  -61.451 1.00 53.71  ? 110 ARG C CD  1 
ATOM   7759  N  NE  . ARG C 1 110 ? -28.159 23.359  -62.835 1.00 47.41  ? 110 ARG C NE  1 
ATOM   7760  C  CZ  . ARG C 1 110 ? -28.902 23.684  -63.883 1.00 53.04  ? 110 ARG C CZ  1 
ATOM   7761  N  NH1 . ARG C 1 110 ? -30.137 24.134  -63.737 1.00 53.88  ? 110 ARG C NH1 1 
ATOM   7762  N  NH2 . ARG C 1 110 ? -28.395 23.550  -65.106 1.00 52.48  ? 110 ARG C NH2 1 
ATOM   7763  N  N   . LEU C 1 111 ? -26.086 20.478  -57.369 1.00 32.93  ? 111 LEU C N   1 
ATOM   7764  C  CA  . LEU C 1 111 ? -25.451 19.253  -56.898 1.00 26.78  ? 111 LEU C CA  1 
ATOM   7765  C  C   . LEU C 1 111 ? -26.430 18.088  -57.045 1.00 34.22  ? 111 LEU C C   1 
ATOM   7766  O  O   . LEU C 1 111 ? -27.640 18.252  -56.882 1.00 33.97  ? 111 LEU C O   1 
ATOM   7767  C  CB  . LEU C 1 111 ? -25.034 19.366  -55.430 1.00 29.53  ? 111 LEU C CB  1 
ATOM   7768  C  CG  . LEU C 1 111 ? -24.098 20.503  -55.053 1.00 30.51  ? 111 LEU C CG  1 
ATOM   7769  C  CD1 . LEU C 1 111 ? -23.967 20.583  -53.532 1.00 31.80  ? 111 LEU C CD1 1 
ATOM   7770  C  CD2 . LEU C 1 111 ? -22.751 20.264  -55.704 1.00 28.06  ? 111 LEU C CD2 1 
ATOM   7771  N  N   . ARG C 1 112 ? -25.909 16.903  -57.346 1.00 35.60  ? 112 ARG C N   1 
ATOM   7772  C  CA  . ARG C 1 112 ? -26.750 15.725  -57.520 1.00 31.64  ? 112 ARG C CA  1 
ATOM   7773  C  C   . ARG C 1 112 ? -26.663 14.845  -56.273 1.00 37.20  ? 112 ARG C C   1 
ATOM   7774  O  O   . ARG C 1 112 ? -25.584 14.336  -55.939 1.00 33.41  ? 112 ARG C O   1 
ATOM   7775  C  CB  . ARG C 1 112 ? -26.345 14.941  -58.772 1.00 29.21  ? 112 ARG C CB  1 
ATOM   7776  C  CG  . ARG C 1 112 ? -26.426 15.755  -60.079 1.00 32.62  ? 112 ARG C CG  1 
ATOM   7777  C  CD  . ARG C 1 112 ? -26.481 14.837  -61.313 1.00 28.40  ? 112 ARG C CD  1 
ATOM   7778  N  NE  . ARG C 1 112 ? -25.424 13.834  -61.253 1.00 29.65  ? 112 ARG C NE  1 
ATOM   7779  C  CZ  . ARG C 1 112 ? -24.144 14.081  -61.494 1.00 28.90  ? 112 ARG C CZ  1 
ATOM   7780  N  NH1 . ARG C 1 112 ? -23.741 15.270  -61.909 1.00 28.81  ? 112 ARG C NH1 1 
ATOM   7781  N  NH2 . ARG C 1 112 ? -23.246 13.121  -61.291 1.00 28.04  ? 112 ARG C NH2 1 
ATOM   7782  N  N   . MET C 1 113 ? -27.797 14.669  -55.584 1.00 36.50  ? 113 MET C N   1 
ATOM   7783  C  CA  . MET C 1 113 ? -27.900 13.702  -54.492 1.00 40.02  ? 113 MET C CA  1 
ATOM   7784  C  C   . MET C 1 113 ? -28.604 12.460  -55.025 1.00 35.95  ? 113 MET C C   1 
ATOM   7785  O  O   . MET C 1 113 ? -29.822 12.467  -55.228 1.00 40.03  ? 113 MET C O   1 
ATOM   7786  C  CB  . MET C 1 113 ? -28.652 14.248  -53.277 1.00 39.28  ? 113 MET C CB  1 
ATOM   7787  C  CG  . MET C 1 113 ? -28.552 15.725  -52.992 1.00 40.23  ? 113 MET C CG  1 
ATOM   7788  S  SD  . MET C 1 113 ? -26.939 16.417  -53.299 1.00 48.07  ? 113 MET C SD  1 
ATOM   7789  C  CE  . MET C 1 113 ? -27.072 17.958  -52.400 1.00 33.86  ? 113 MET C CE  1 
ATOM   7790  N  N   . SER C 1 114 ? -27.836 11.391  -55.239 1.00 40.29  ? 114 SER C N   1 
ATOM   7791  C  CA  . SER C 1 114 ? -28.400 10.146  -55.745 1.00 41.40  ? 114 SER C CA  1 
ATOM   7792  C  C   . SER C 1 114 ? -29.472 9.578   -54.823 1.00 44.14  ? 114 SER C C   1 
ATOM   7793  O  O   . SER C 1 114 ? -30.322 8.816   -55.284 1.00 41.29  ? 114 SER C O   1 
ATOM   7794  C  CB  . SER C 1 114 ? -27.293 9.110   -55.946 1.00 38.25  ? 114 SER C CB  1 
ATOM   7795  O  OG  . SER C 1 114 ? -26.096 9.710   -56.428 1.00 37.20  ? 114 SER C OG  1 
ATOM   7796  N  N   . TYR C 1 115 ? -29.459 9.936   -53.538 1.00 44.69  ? 115 TYR C N   1 
ATOM   7797  C  CA  . TYR C 1 115 ? -30.434 9.431   -52.586 1.00 45.56  ? 115 TYR C CA  1 
ATOM   7798  C  C   . TYR C 1 115 ? -31.705 10.273  -52.543 1.00 48.20  ? 115 TYR C C   1 
ATOM   7799  O  O   . TYR C 1 115 ? -32.574 10.018  -51.698 1.00 44.92  ? 115 TYR C O   1 
ATOM   7800  C  CB  . TYR C 1 115 ? -29.807 9.346   -51.192 1.00 44.99  ? 115 TYR C CB  1 
ATOM   7801  C  CG  . TYR C 1 115 ? -29.254 10.662  -50.698 1.00 41.89  ? 115 TYR C CG  1 
ATOM   7802  C  CD1 . TYR C 1 115 ? -30.084 11.597  -50.097 1.00 42.59  ? 115 TYR C CD1 1 
ATOM   7803  C  CD2 . TYR C 1 115 ? -27.909 10.969  -50.828 1.00 34.22  ? 115 TYR C CD2 1 
ATOM   7804  C  CE1 . TYR C 1 115 ? -29.596 12.803  -49.639 1.00 46.70  ? 115 TYR C CE1 1 
ATOM   7805  C  CE2 . TYR C 1 115 ? -27.411 12.184  -50.373 1.00 38.10  ? 115 TYR C CE2 1 
ATOM   7806  C  CZ  . TYR C 1 115 ? -28.263 13.096  -49.779 1.00 43.02  ? 115 TYR C CZ  1 
ATOM   7807  O  OH  . TYR C 1 115 ? -27.804 14.309  -49.308 1.00 43.56  ? 115 TYR C OH  1 
ATOM   7808  N  N   . ILE C 1 116 ? -31.829 11.269  -53.419 1.00 45.32  ? 116 ILE C N   1 
ATOM   7809  C  CA  . ILE C 1 116 ? -33.059 12.052  -53.530 1.00 49.97  ? 116 ILE C CA  1 
ATOM   7810  C  C   . ILE C 1 116 ? -33.798 11.615  -54.791 1.00 52.05  ? 116 ILE C C   1 
ATOM   7811  O  O   . ILE C 1 116 ? -33.164 11.405  -55.837 1.00 50.29  ? 116 ILE C O   1 
ATOM   7812  C  CB  . ILE C 1 116 ? -32.769 13.564  -53.523 1.00 47.91  ? 116 ILE C CB  1 
ATOM   7813  C  CG1 . ILE C 1 116 ? -32.232 13.985  -52.153 1.00 43.27  ? 116 ILE C CG1 1 
ATOM   7814  C  CG2 . ILE C 1 116 ? -34.021 14.372  -53.882 1.00 47.31  ? 116 ILE C CG2 1 
ATOM   7815  C  CD1 . ILE C 1 116 ? -32.414 15.448  -51.837 1.00 46.21  ? 116 ILE C CD1 1 
ATOM   7816  N  N   . PRO C 1 117 ? -35.121 11.428  -54.727 1.00 53.85  ? 117 PRO C N   1 
ATOM   7817  C  CA  . PRO C 1 117 ? -35.884 11.049  -55.925 1.00 54.90  ? 117 PRO C CA  1 
ATOM   7818  C  C   . PRO C 1 117 ? -35.680 12.030  -57.074 1.00 55.37  ? 117 PRO C C   1 
ATOM   7819  O  O   . PRO C 1 117 ? -35.593 13.241  -56.875 1.00 57.90  ? 117 PRO C O   1 
ATOM   7820  C  CB  . PRO C 1 117 ? -37.334 11.052  -55.429 1.00 59.05  ? 117 PRO C CB  1 
ATOM   7821  C  CG  . PRO C 1 117 ? -37.216 10.739  -53.965 1.00 58.70  ? 117 PRO C CG  1 
ATOM   7822  C  CD  . PRO C 1 117 ? -35.956 11.428  -53.512 1.00 51.14  ? 117 PRO C CD  1 
ATOM   7823  N  N   . GLN C 1 118 ? -35.643 11.483  -58.292 1.00 56.65  ? 118 GLN C N   1 
ATOM   7824  C  CA  . GLN C 1 118 ? -35.095 12.194  -59.447 1.00 59.21  ? 118 GLN C CA  1 
ATOM   7825  C  C   . GLN C 1 118 ? -35.930 13.408  -59.856 1.00 63.28  ? 118 GLN C C   1 
ATOM   7826  O  O   . GLN C 1 118 ? -35.378 14.389  -60.374 1.00 62.14  ? 118 GLN C O   1 
ATOM   7827  C  CB  . GLN C 1 118 ? -34.955 11.217  -60.618 1.00 60.53  ? 118 GLN C CB  1 
ATOM   7828  C  CG  . GLN C 1 118 ? -34.475 11.834  -61.922 1.00 63.84  ? 118 GLN C CG  1 
ATOM   7829  C  CD  . GLN C 1 118 ? -32.961 11.964  -61.972 1.00 64.90  ? 118 GLN C CD  1 
ATOM   7830  O  OE1 . GLN C 1 118 ? -32.399 12.974  -61.542 1.00 62.82  ? 118 GLN C OE1 1 
ATOM   7831  N  NE2 . GLN C 1 118 ? -32.291 10.933  -62.483 1.00 63.49  ? 118 GLN C NE2 1 
ATOM   7832  N  N   . GLU C 1 119 ? -37.247 13.372  -59.652 1.00 66.53  ? 119 GLU C N   1 
ATOM   7833  C  CA  . GLU C 1 119 ? -38.068 14.521  -60.027 1.00 66.94  ? 119 GLU C CA  1 
ATOM   7834  C  C   . GLU C 1 119 ? -37.800 15.735  -59.143 1.00 66.76  ? 119 GLU C C   1 
ATOM   7835  O  O   . GLU C 1 119 ? -38.067 16.867  -59.567 1.00 71.87  ? 119 GLU C O   1 
ATOM   7836  C  CB  . GLU C 1 119 ? -39.551 14.151  -59.984 1.00 68.35  ? 119 GLU C CB  1 
ATOM   7837  C  CG  . GLU C 1 119 ? -39.994 13.539  -58.667 1.00 70.23  ? 119 GLU C CG  1 
ATOM   7838  C  CD  . GLU C 1 119 ? -39.983 12.018  -58.704 1.00 74.31  ? 119 GLU C CD  1 
ATOM   7839  O  OE1 . GLU C 1 119 ? -39.604 11.444  -59.753 1.00 70.70  ? 119 GLU C OE1 1 
ATOM   7840  O  OE2 . GLU C 1 119 ? -40.335 11.397  -57.676 1.00 75.25  ? 119 GLU C OE2 1 
ATOM   7841  N  N   . HIS C 1 120 ? -37.281 15.524  -57.929 1.00 65.73  ? 120 HIS C N   1 
ATOM   7842  C  CA  . HIS C 1 120 ? -36.820 16.600  -57.058 1.00 64.68  ? 120 HIS C CA  1 
ATOM   7843  C  C   . HIS C 1 120 ? -35.334 16.877  -57.217 1.00 59.52  ? 120 HIS C C   1 
ATOM   7844  O  O   . HIS C 1 120 ? -34.657 17.192  -56.226 1.00 49.98  ? 120 HIS C O   1 
ATOM   7845  C  CB  . HIS C 1 120 ? -37.114 16.271  -55.595 1.00 62.61  ? 120 HIS C CB  1 
ATOM   7846  C  CG  . HIS C 1 120 ? -38.570 16.204  -55.271 1.00 70.32  ? 120 HIS C CG  1 
ATOM   7847  N  ND1 . HIS C 1 120 ? -39.545 16.156  -56.244 1.00 68.33  ? 120 HIS C ND1 1 
ATOM   7848  C  CD2 . HIS C 1 120 ? -39.221 16.209  -54.083 1.00 64.25  ? 120 HIS C CD2 1 
ATOM   7849  C  CE1 . HIS C 1 120 ? -40.731 16.102  -55.668 1.00 69.25  ? 120 HIS C CE1 1 
ATOM   7850  N  NE2 . HIS C 1 120 ? -40.564 16.143  -54.358 1.00 71.60  ? 120 HIS C NE2 1 
ATOM   7851  N  N   . GLN C 1 121 ? -34.798 16.749  -58.424 1.00 58.65  ? 121 GLN C N   1 
ATOM   7852  C  CA  . GLN C 1 121 ? -33.357 16.796  -58.599 1.00 55.71  ? 121 GLN C CA  1 
ATOM   7853  C  C   . GLN C 1 121 ? -33.013 17.462  -59.921 1.00 53.96  ? 121 GLN C C   1 
ATOM   7854  O  O   . GLN C 1 121 ? -33.741 17.296  -60.908 1.00 58.25  ? 121 GLN C O   1 
ATOM   7855  C  CB  . GLN C 1 121 ? -32.746 15.387  -58.537 1.00 50.46  ? 121 GLN C CB  1 
ATOM   7856  C  CG  . GLN C 1 121 ? -32.467 14.935  -57.123 1.00 47.05  ? 121 GLN C CG  1 
ATOM   7857  C  CD  . GLN C 1 121 ? -31.249 15.618  -56.531 1.00 44.65  ? 121 GLN C CD  1 
ATOM   7858  O  OE1 . GLN C 1 121 ? -30.121 15.217  -56.801 1.00 43.31  ? 121 GLN C OE1 1 
ATOM   7859  N  NE2 . GLN C 1 121 ? -31.470 16.653  -55.717 1.00 42.15  ? 121 GLN C NE2 1 
ATOM   7860  N  N   . PRO C 1 122 ? -31.883 18.201  -59.982 1.00 50.43  ? 122 PRO C N   1 
ATOM   7861  C  CA  . PRO C 1 122 ? -30.845 18.308  -58.945 1.00 46.02  ? 122 PRO C CA  1 
ATOM   7862  C  C   . PRO C 1 122 ? -31.228 19.131  -57.731 1.00 43.81  ? 122 PRO C C   1 
ATOM   7863  O  O   . PRO C 1 122 ? -32.290 19.744  -57.711 1.00 48.67  ? 122 PRO C O   1 
ATOM   7864  C  CB  . PRO C 1 122 ? -29.703 19.001  -59.677 1.00 44.29  ? 122 PRO C CB  1 
ATOM   7865  C  CG  . PRO C 1 122 ? -30.393 19.880  -60.653 1.00 47.78  ? 122 PRO C CG  1 
ATOM   7866  C  CD  . PRO C 1 122 ? -31.581 19.073  -61.132 1.00 42.14  ? 122 PRO C CD  1 
ATOM   7867  N  N   . SER C 1 123 ? -30.358 19.125  -56.726 1.00 40.64  ? 123 SER C N   1 
ATOM   7868  C  CA  . SER C 1 123 ? -30.483 20.043  -55.604 1.00 41.93  ? 123 SER C CA  1 
ATOM   7869  C  C   . SER C 1 123 ? -29.931 21.388  -56.037 1.00 40.93  ? 123 SER C C   1 
ATOM   7870  O  O   . SER C 1 123 ? -28.906 21.449  -56.715 1.00 41.70  ? 123 SER C O   1 
ATOM   7871  C  CB  . SER C 1 123 ? -29.716 19.519  -54.384 1.00 38.48  ? 123 SER C CB  1 
ATOM   7872  O  OG  . SER C 1 123 ? -30.293 18.327  -53.876 1.00 39.50  ? 123 SER C OG  1 
ATOM   7873  N  N   . THR C 1 124 ? -30.612 22.469  -55.661 1.00 41.39  ? 124 THR C N   1 
ATOM   7874  C  CA  . THR C 1 124 ? -30.276 23.789  -56.179 1.00 39.56  ? 124 THR C CA  1 
ATOM   7875  C  C   . THR C 1 124 ? -30.186 24.806  -55.050 1.00 40.61  ? 124 THR C C   1 
ATOM   7876  O  O   . THR C 1 124 ? -31.076 24.878  -54.196 1.00 43.25  ? 124 THR C O   1 
ATOM   7877  C  CB  . THR C 1 124 ? -31.301 24.243  -57.220 1.00 40.58  ? 124 THR C CB  1 
ATOM   7878  O  OG1 . THR C 1 124 ? -31.171 23.429  -58.399 1.00 45.02  ? 124 THR C OG1 1 
ATOM   7879  C  CG2 . THR C 1 124 ? -31.054 25.696  -57.592 1.00 43.17  ? 124 THR C CG2 1 
ATOM   7880  N  N   . TYR C 1 125 ? -29.113 25.592  -55.059 1.00 32.19  ? 125 TYR C N   1 
ATOM   7881  C  CA  . TYR C 1 125 ? -28.843 26.597  -54.036 1.00 36.17  ? 125 TYR C CA  1 
ATOM   7882  C  C   . TYR C 1 125 ? -28.646 27.934  -54.724 1.00 40.78  ? 125 TYR C C   1 
ATOM   7883  O  O   . TYR C 1 125 ? -27.640 28.145  -55.406 1.00 42.33  ? 125 TYR C O   1 
ATOM   7884  C  CB  . TYR C 1 125 ? -27.606 26.237  -53.210 1.00 35.93  ? 125 TYR C CB  1 
ATOM   7885  C  CG  . TYR C 1 125 ? -27.603 24.808  -52.746 1.00 35.37  ? 125 TYR C CG  1 
ATOM   7886  C  CD1 . TYR C 1 125 ? -27.308 23.774  -53.630 1.00 36.45  ? 125 TYR C CD1 1 
ATOM   7887  C  CD2 . TYR C 1 125 ? -27.908 24.481  -51.445 1.00 36.95  ? 125 TYR C CD2 1 
ATOM   7888  C  CE1 . TYR C 1 125 ? -27.318 22.467  -53.234 1.00 34.55  ? 125 TYR C CE1 1 
ATOM   7889  C  CE2 . TYR C 1 125 ? -27.912 23.161  -51.033 1.00 33.03  ? 125 TYR C CE2 1 
ATOM   7890  C  CZ  . TYR C 1 125 ? -27.614 22.161  -51.946 1.00 35.01  ? 125 TYR C CZ  1 
ATOM   7891  O  OH  . TYR C 1 125 ? -27.595 20.844  -51.582 1.00 40.65  ? 125 TYR C OH  1 
ATOM   7892  N  N   . ARG C 1 126 ? -29.594 28.836  -54.547 1.00 39.20  ? 126 ARG C N   1 
ATOM   7893  C  CA  . ARG C 1 126 ? -29.487 30.182  -55.077 1.00 38.74  ? 126 ARG C CA  1 
ATOM   7894  C  C   . ARG C 1 126 ? -29.212 31.100  -53.903 1.00 37.68  ? 126 ARG C C   1 
ATOM   7895  O  O   . ARG C 1 126 ? -29.986 31.114  -52.944 1.00 44.39  ? 126 ARG C O   1 
ATOM   7896  C  CB  . ARG C 1 126 ? -30.772 30.588  -55.794 1.00 41.49  ? 126 ARG C CB  1 
ATOM   7897  C  CG  . ARG C 1 126 ? -31.277 29.554  -56.791 1.00 44.15  ? 126 ARG C CG  1 
ATOM   7898  C  CD  . ARG C 1 126 ? -32.740 29.803  -57.132 1.00 47.98  ? 126 ARG C CD  1 
ATOM   7899  N  NE  . ARG C 1 126 ? -33.234 28.829  -58.093 1.00 54.36  ? 126 ARG C NE  1 
ATOM   7900  C  CZ  . ARG C 1 126 ? -32.975 28.871  -59.393 1.00 58.18  ? 126 ARG C CZ  1 
ATOM   7901  N  NH1 . ARG C 1 126 ? -32.253 29.847  -59.921 1.00 57.92  ? 126 ARG C NH1 1 
ATOM   7902  N  NH2 . ARG C 1 126 ? -33.451 27.909  -60.182 1.00 56.64  ? 126 ARG C NH2 1 
ATOM   7903  N  N   . VAL C 1 127 ? -28.099 31.833  -53.955 1.00 37.37  ? 127 VAL C N   1 
ATOM   7904  C  CA  . VAL C 1 127 ? -27.830 32.883  -52.976 1.00 32.81  ? 127 VAL C CA  1 
ATOM   7905  C  C   . VAL C 1 127 ? -27.207 34.079  -53.682 1.00 31.44  ? 127 VAL C C   1 
ATOM   7906  O  O   . VAL C 1 127 ? -26.683 33.982  -54.795 1.00 30.62  ? 127 VAL C O   1 
ATOM   7907  C  CB  . VAL C 1 127 ? -26.914 32.438  -51.810 1.00 34.94  ? 127 VAL C CB  1 
ATOM   7908  C  CG1 . VAL C 1 127 ? -27.628 31.425  -50.894 1.00 43.09  ? 127 VAL C CG1 1 
ATOM   7909  C  CG2 . VAL C 1 127 ? -25.617 31.885  -52.335 1.00 37.86  ? 127 VAL C CG2 1 
ATOM   7910  N  N   . THR C 1 128 ? -27.261 35.213  -52.993 1.00 27.67  ? 128 THR C N   1 
ATOM   7911  C  CA  . THR C 1 128 ? -26.846 36.497  -53.513 1.00 35.77  ? 128 THR C CA  1 
ATOM   7912  C  C   . THR C 1 128 ? -26.057 37.189  -52.417 1.00 34.36  ? 128 THR C C   1 
ATOM   7913  O  O   . THR C 1 128 ? -26.468 37.170  -51.258 1.00 33.94  ? 128 THR C O   1 
ATOM   7914  C  CB  . THR C 1 128 ? -28.075 37.323  -53.936 1.00 41.37  ? 128 THR C CB  1 
ATOM   7915  O  OG1 . THR C 1 128 ? -28.822 36.600  -54.935 1.00 36.73  ? 128 THR C OG1 1 
ATOM   7916  C  CG2 . THR C 1 128 ? -27.663 38.696  -54.483 1.00 37.35  ? 128 THR C CG2 1 
ATOM   7917  N  N   . LYS C 1 129 ? -24.914 37.768  -52.767 1.00 34.76  ? 129 LYS C N   1 
ATOM   7918  C  CA  . LYS C 1 129 ? -24.109 38.437  -51.757 1.00 33.45  ? 129 LYS C CA  1 
ATOM   7919  C  C   . LYS C 1 129 ? -23.432 39.663  -52.351 1.00 31.87  ? 129 LYS C C   1 
ATOM   7920  O  O   . LYS C 1 129 ? -22.982 39.640  -53.492 1.00 33.99  ? 129 LYS C O   1 
ATOM   7921  C  CB  . LYS C 1 129 ? -23.055 37.484  -51.172 1.00 31.13  ? 129 LYS C CB  1 
ATOM   7922  C  CG  . LYS C 1 129 ? -22.186 38.096  -50.065 1.00 31.77  ? 129 LYS C CG  1 
ATOM   7923  C  CD  . LYS C 1 129 ? -21.583 37.005  -49.183 1.00 35.84  ? 129 LYS C CD  1 
ATOM   7924  C  CE  . LYS C 1 129 ? -20.304 37.439  -48.462 1.00 35.53  ? 129 LYS C CE  1 
ATOM   7925  N  NZ  . LYS C 1 129 ? -20.603 38.225  -47.243 1.00 37.60  ? 129 LYS C NZ  1 
ATOM   7926  N  N   . HIS C 1 130 ? -23.362 40.729  -51.568 1.00 30.00  ? 130 HIS C N   1 
ATOM   7927  C  CA  . HIS C 1 130 ? -22.541 41.882  -51.899 1.00 32.47  ? 130 HIS C CA  1 
ATOM   7928  C  C   . HIS C 1 130 ? -21.137 41.592  -51.389 1.00 33.99  ? 130 HIS C C   1 
ATOM   7929  O  O   . HIS C 1 130 ? -20.917 41.534  -50.177 1.00 31.80  ? 130 HIS C O   1 
ATOM   7930  C  CB  . HIS C 1 130 ? -23.118 43.155  -51.274 1.00 30.34  ? 130 HIS C CB  1 
ATOM   7931  C  CG  . HIS C 1 130 ? -24.323 43.680  -51.994 1.00 35.92  ? 130 HIS C CG  1 
ATOM   7932  N  ND1 . HIS C 1 130 ? -25.598 43.212  -51.750 1.00 44.35  ? 130 HIS C ND1 1 
ATOM   7933  C  CD2 . HIS C 1 130 ? -24.447 44.625  -52.955 1.00 38.90  ? 130 HIS C CD2 1 
ATOM   7934  C  CE1 . HIS C 1 130 ? -26.455 43.846  -52.531 1.00 42.45  ? 130 HIS C CE1 1 
ATOM   7935  N  NE2 . HIS C 1 130 ? -25.781 44.707  -53.274 1.00 46.15  ? 130 HIS C NE2 1 
ATOM   7936  N  N   . VAL C 1 131 ? -20.192 41.381  -52.312 1.00 29.36  ? 131 VAL C N   1 
ATOM   7937  C  CA  . VAL C 1 131 ? -18.825 41.005  -51.969 1.00 27.72  ? 131 VAL C CA  1 
ATOM   7938  C  C   . VAL C 1 131 ? -17.871 42.022  -52.565 1.00 28.85  ? 131 VAL C C   1 
ATOM   7939  O  O   . VAL C 1 131 ? -18.113 42.569  -53.648 1.00 30.17  ? 131 VAL C O   1 
ATOM   7940  C  CB  . VAL C 1 131 ? -18.468 39.584  -52.457 1.00 29.09  ? 131 VAL C CB  1 
ATOM   7941  C  CG1 . VAL C 1 131 ? -18.899 38.579  -51.456 1.00 33.84  ? 131 VAL C CG1 1 
ATOM   7942  C  CG2 . VAL C 1 131 ? -19.157 39.302  -53.786 1.00 31.39  ? 131 VAL C CG2 1 
ATOM   7943  N  N   . THR C 1 132 ? -16.768 42.264  -51.866 1.00 25.10  ? 132 THR C N   1 
ATOM   7944  C  CA  . THR C 1 132 ? -15.835 43.312  -52.259 1.00 28.97  ? 132 THR C CA  1 
ATOM   7945  C  C   . THR C 1 132 ? -14.627 42.684  -52.925 1.00 28.86  ? 132 THR C C   1 
ATOM   7946  O  O   . THR C 1 132 ? -13.963 41.827  -52.338 1.00 25.72  ? 132 THR C O   1 
ATOM   7947  C  CB  . THR C 1 132 ? -15.430 44.171  -51.063 1.00 25.65  ? 132 THR C CB  1 
ATOM   7948  O  OG1 . THR C 1 132 ? -16.621 44.669  -50.453 1.00 28.27  ? 132 THR C OG1 1 
ATOM   7949  C  CG2 . THR C 1 132 ? -14.582 45.370  -51.504 1.00 28.31  ? 132 THR C CG2 1 
ATOM   7950  N  N   . LEU C 1 133 ? -14.361 43.108  -54.156 1.00 27.07  ? 133 LEU C N   1 
ATOM   7951  C  CA  . LEU C 1 133 ? -13.280 42.540  -54.944 1.00 26.03  ? 133 LEU C CA  1 
ATOM   7952  C  C   . LEU C 1 133 ? -11.953 42.909  -54.302 1.00 24.46  ? 133 LEU C C   1 
ATOM   7953  O  O   . LEU C 1 133 ? -11.813 43.998  -53.736 1.00 29.31  ? 133 LEU C O   1 
ATOM   7954  C  CB  . LEU C 1 133 ? -13.358 43.083  -56.377 1.00 29.20  ? 133 LEU C CB  1 
ATOM   7955  C  CG  . LEU C 1 133 ? -12.406 42.616  -57.478 1.00 27.49  ? 133 LEU C CG  1 
ATOM   7956  C  CD1 . LEU C 1 133 ? -13.106 41.541  -58.303 1.00 29.08  ? 133 LEU C CD1 1 
ATOM   7957  C  CD2 . LEU C 1 133 ? -11.974 43.785  -58.367 1.00 27.05  ? 133 LEU C CD2 1 
ATOM   7958  N  N   . ALA C 1 134 ? -10.997 41.981  -54.328 1.00 23.06  ? 134 ALA C N   1 
ATOM   7959  C  CA  . ALA C 1 134 ? -9.645  42.331  -53.919 1.00 21.69  ? 134 ALA C CA  1 
ATOM   7960  C  C   . ALA C 1 134 ? -9.217  43.583  -54.685 1.00 32.16  ? 134 ALA C C   1 
ATOM   7961  O  O   . ALA C 1 134 ? -9.410  43.648  -55.910 1.00 29.82  ? 134 ALA C O   1 
ATOM   7962  C  CB  . ALA C 1 134 ? -8.664  41.189  -54.189 1.00 22.25  ? 134 ALA C CB  1 
ATOM   7963  N  N   . PRO C 1 135 ? -8.690  44.601  -54.007 1.00 30.44  ? 135 PRO C N   1 
ATOM   7964  C  CA  . PRO C 1 135 ? -8.451  45.895  -54.663 1.00 33.54  ? 135 PRO C CA  1 
ATOM   7965  C  C   . PRO C 1 135 ? -7.462  45.835  -55.829 1.00 31.51  ? 135 PRO C C   1 
ATOM   7966  O  O   . PRO C 1 135 ? -6.394  45.228  -55.738 1.00 29.37  ? 135 PRO C O   1 
ATOM   7967  C  CB  . PRO C 1 135 ? -7.919  46.756  -53.517 1.00 26.83  ? 135 PRO C CB  1 
ATOM   7968  C  CG  . PRO C 1 135 ? -8.633  46.200  -52.304 1.00 29.86  ? 135 PRO C CG  1 
ATOM   7969  C  CD  . PRO C 1 135 ? -8.684  44.722  -52.534 1.00 29.99  ? 135 PRO C CD  1 
ATOM   7970  N  N   . GLU C 1 136 ? -7.831  46.501  -56.929 1.00 35.28  ? 136 GLU C N   1 
ATOM   7971  C  CA  . GLU C 1 136 ? -6.947  46.740  -58.069 1.00 31.30  ? 136 GLU C CA  1 
ATOM   7972  C  C   . GLU C 1 136 ? -6.195  48.055  -57.955 1.00 31.94  ? 136 GLU C C   1 
ATOM   7973  O  O   . GLU C 1 136 ? -5.102  48.187  -58.516 1.00 27.43  ? 136 GLU C O   1 
ATOM   7974  C  CB  . GLU C 1 136 ? -7.746  46.733  -59.375 1.00 29.37  ? 136 GLU C CB  1 
ATOM   7975  C  CG  . GLU C 1 136 ? -8.414  45.397  -59.689 1.00 32.79  ? 136 GLU C CG  1 
ATOM   7976  C  CD  . GLU C 1 136 ? -7.402  44.375  -60.167 1.00 36.76  ? 136 GLU C CD  1 
ATOM   7977  O  OE1 . GLU C 1 136 ? -6.231  44.762  -60.353 1.00 41.80  ? 136 GLU C OE1 1 
ATOM   7978  O  OE2 . GLU C 1 136 ? -7.760  43.195  -60.356 1.00 32.18  ? 136 GLU C OE2 1 
ATOM   7979  N  N   . ALA C 1 137 ? -6.762  49.020  -57.227 1.00 33.74  ? 137 ALA C N   1 
ATOM   7980  C  CA  . ALA C 1 137 ? -6.130  50.312  -57.011 1.00 25.40  ? 137 ALA C CA  1 
ATOM   7981  C  C   . ALA C 1 137 ? -4.768  50.152  -56.349 1.00 30.59  ? 137 ALA C C   1 
ATOM   7982  O  O   . ALA C 1 137 ? -4.572  49.291  -55.485 1.00 31.96  ? 137 ALA C O   1 
ATOM   7983  C  CB  . ALA C 1 137 ? -7.037  51.192  -56.138 1.00 27.21  ? 137 ALA C CB  1 
ATOM   7984  N  N   . SER C 1 138 ? -3.828  51.018  -56.727 1.00 29.25  ? 138 SER C N   1 
ATOM   7985  C  CA  . SER C 1 138 ? -2.489  50.942  -56.153 1.00 31.52  ? 138 SER C CA  1 
ATOM   7986  C  C   . SER C 1 138 ? -2.473  51.423  -54.709 1.00 33.78  ? 138 SER C C   1 
ATOM   7987  O  O   . SER C 1 138 ? -1.996  50.722  -53.808 1.00 33.99  ? 138 SER C O   1 
ATOM   7988  C  CB  . SER C 1 138 ? -1.516  51.763  -56.980 1.00 31.68  ? 138 SER C CB  1 
ATOM   7989  O  OG  . SER C 1 138 ? -0.378  52.053  -56.194 1.00 39.18  ? 138 SER C OG  1 
ATOM   7990  N  N   . GLY C 1 139 ? -2.960  52.639  -54.476 1.00 33.53  ? 139 GLY C N   1 
ATOM   7991  C  CA  . GLY C 1 139 ? -3.031  53.190  -53.141 1.00 33.03  ? 139 GLY C CA  1 
ATOM   7992  C  C   . GLY C 1 139 ? -1.776  53.868  -52.672 1.00 29.17  ? 139 GLY C C   1 
ATOM   7993  O  O   . GLY C 1 139 ? -1.717  54.294  -51.507 1.00 30.04  ? 139 GLY C O   1 
ATOM   7994  N  N   . ALA C 1 140 ? -0.777  53.981  -53.530 1.00 32.20  ? 140 ALA C N   1 
ATOM   7995  C  CA  . ALA C 1 140 ? 0.459   54.684  -53.214 1.00 29.00  ? 140 ALA C CA  1 
ATOM   7996  C  C   . ALA C 1 140 ? 0.107   56.090  -52.733 1.00 29.07  ? 140 ALA C C   1 
ATOM   7997  O  O   . ALA C 1 140 ? -0.902  56.665  -53.157 1.00 27.23  ? 140 ALA C O   1 
ATOM   7998  C  CB  . ALA C 1 140 ? 1.382   54.704  -54.435 1.00 30.77  ? 140 ALA C CB  1 
ATOM   7999  N  N   . PRO C 1 141 ? 0.886   56.669  -51.833 1.00 26.02  ? 141 PRO C N   1 
ATOM   8000  C  CA  . PRO C 1 141 ? 2.149   56.185  -51.296 1.00 27.57  ? 141 PRO C CA  1 
ATOM   8001  C  C   . PRO C 1 141 ? 2.006   55.470  -49.973 1.00 27.77  ? 141 PRO C C   1 
ATOM   8002  O  O   . PRO C 1 141 ? 3.008   55.301  -49.280 1.00 29.71  ? 141 PRO C O   1 
ATOM   8003  C  CB  . PRO C 1 141 ? 2.921   57.482  -51.085 1.00 25.54  ? 141 PRO C CB  1 
ATOM   8004  C  CG  . PRO C 1 141 ? 1.850   58.402  -50.602 1.00 26.43  ? 141 PRO C CG  1 
ATOM   8005  C  CD  . PRO C 1 141 ? 0.571   58.009  -51.324 1.00 24.60  ? 141 PRO C CD  1 
ATOM   8006  N  N   . PHE C 1 142 ? 0.789   55.120  -49.580 1.00 30.17  ? 142 PHE C N   1 
ATOM   8007  C  CA  . PHE C 1 142 ? 0.631   54.550  -48.252 1.00 29.54  ? 142 PHE C CA  1 
ATOM   8008  C  C   . PHE C 1 142 ? 0.983   53.065  -48.279 1.00 33.19  ? 142 PHE C C   1 
ATOM   8009  O  O   . PHE C 1 142 ? 1.160   52.461  -49.342 1.00 29.59  ? 142 PHE C O   1 
ATOM   8010  C  CB  . PHE C 1 142 ? -0.795  54.790  -47.742 1.00 33.96  ? 142 PHE C CB  1 
ATOM   8011  C  CG  . PHE C 1 142 ? -1.198  56.237  -47.762 1.00 33.05  ? 142 PHE C CG  1 
ATOM   8012  C  CD1 . PHE C 1 142 ? -0.440  57.192  -47.086 1.00 34.49  ? 142 PHE C CD1 1 
ATOM   8013  C  CD2 . PHE C 1 142 ? -2.282  56.657  -48.518 1.00 31.93  ? 142 PHE C CD2 1 
ATOM   8014  C  CE1 . PHE C 1 142 ? -0.785  58.535  -47.123 1.00 31.29  ? 142 PHE C CE1 1 
ATOM   8015  C  CE2 . PHE C 1 142 ? -2.629  58.005  -48.567 1.00 33.98  ? 142 PHE C CE2 1 
ATOM   8016  C  CZ  . PHE C 1 142 ? -1.884  58.947  -47.861 1.00 26.42  ? 142 PHE C CZ  1 
ATOM   8017  N  N   . ARG C 1 143 ? 1.120   52.487  -47.084 1.00 34.34  ? 143 ARG C N   1 
ATOM   8018  C  CA  . ARG C 1 143 ? 1.286   51.053  -46.895 1.00 27.45  ? 143 ARG C CA  1 
ATOM   8019  C  C   . ARG C 1 143 ? 0.045   50.518  -46.200 1.00 26.55  ? 143 ARG C C   1 
ATOM   8020  O  O   . ARG C 1 143 ? -0.573  51.204  -45.379 1.00 29.46  ? 143 ARG C O   1 
ATOM   8021  C  CB  . ARG C 1 143 ? 2.541   50.736  -46.072 1.00 30.66  ? 143 ARG C CB  1 
ATOM   8022  C  CG  . ARG C 1 143 ? 3.720   51.657  -46.385 1.00 34.61  ? 143 ARG C CG  1 
ATOM   8023  C  CD  . ARG C 1 143 ? 5.042   51.063  -45.926 1.00 35.44  ? 143 ARG C CD  1 
ATOM   8024  N  NE  . ARG C 1 143 ? 5.182   49.688  -46.388 1.00 43.33  ? 143 ARG C NE  1 
ATOM   8025  C  CZ  . ARG C 1 143 ? 5.964   48.783  -45.818 1.00 41.85  ? 143 ARG C CZ  1 
ATOM   8026  N  NH1 . ARG C 1 143 ? 6.719   49.084  -44.769 1.00 38.70  ? 143 ARG C NH1 1 
ATOM   8027  N  NH2 . ARG C 1 143 ? 5.994   47.548  -46.316 1.00 40.75  ? 143 ARG C NH2 1 
ATOM   8028  N  N   . TYR C 1 144 ? -0.343  49.303  -46.547 1.00 29.55  ? 144 TYR C N   1 
ATOM   8029  C  CA  . TYR C 1 144 ? -1.687  48.823  -46.239 1.00 25.37  ? 144 TYR C CA  1 
ATOM   8030  C  C   . TYR C 1 144 ? -1.627  47.639  -45.284 1.00 25.67  ? 144 TYR C C   1 
ATOM   8031  O  O   . TYR C 1 144 ? -0.847  46.699  -45.490 1.00 24.41  ? 144 TYR C O   1 
ATOM   8032  C  CB  . TYR C 1 144 ? -2.427  48.505  -47.533 1.00 28.80  ? 144 TYR C CB  1 
ATOM   8033  C  CG  . TYR C 1 144 ? -2.708  49.811  -48.240 1.00 30.76  ? 144 TYR C CG  1 
ATOM   8034  C  CD1 . TYR C 1 144 ? -3.821  50.567  -47.898 1.00 33.80  ? 144 TYR C CD1 1 
ATOM   8035  C  CD2 . TYR C 1 144 ? -1.826  50.332  -49.170 1.00 33.23  ? 144 TYR C CD2 1 
ATOM   8036  C  CE1 . TYR C 1 144 ? -4.081  51.787  -48.498 1.00 35.15  ? 144 TYR C CE1 1 
ATOM   8037  C  CE2 . TYR C 1 144 ? -2.072  51.575  -49.784 1.00 32.54  ? 144 TYR C CE2 1 
ATOM   8038  C  CZ  . TYR C 1 144 ? -3.205  52.289  -49.439 1.00 34.42  ? 144 TYR C CZ  1 
ATOM   8039  O  OH  . TYR C 1 144 ? -3.489  53.497  -50.014 1.00 29.77  ? 144 TYR C OH  1 
ATOM   8040  N  N   . GLY C 1 145 ? -2.437  47.714  -44.225 1.00 26.94  ? 145 GLY C N   1 
ATOM   8041  C  CA  . GLY C 1 145 ? -2.359  46.766  -43.131 1.00 24.74  ? 145 GLY C CA  1 
ATOM   8042  C  C   . GLY C 1 145 ? -3.726  46.542  -42.531 1.00 26.13  ? 145 GLY C C   1 
ATOM   8043  O  O   . GLY C 1 145 ? -4.691  47.256  -42.825 1.00 23.72  ? 145 GLY C O   1 
ATOM   8044  N  N   . VAL C 1 146 ? -3.792  45.538  -41.663 1.00 25.84  ? 146 VAL C N   1 
ATOM   8045  C  CA  . VAL C 1 146 ? -5.000  45.218  -40.919 1.00 25.45  ? 146 VAL C CA  1 
ATOM   8046  C  C   . VAL C 1 146 ? -4.586  44.850  -39.504 1.00 30.95  ? 146 VAL C C   1 
ATOM   8047  O  O   . VAL C 1 146 ? -3.681  44.027  -39.315 1.00 28.80  ? 146 VAL C O   1 
ATOM   8048  C  CB  . VAL C 1 146 ? -5.777  44.053  -41.559 1.00 30.88  ? 146 VAL C CB  1 
ATOM   8049  C  CG1 . VAL C 1 146 ? -6.803  43.465  -40.568 1.00 24.76  ? 146 VAL C CG1 1 
ATOM   8050  C  CG2 . VAL C 1 146 ? -6.440  44.494  -42.856 1.00 28.85  ? 146 VAL C CG2 1 
ATOM   8051  N  N   . SER C 1 147 ? -5.222  45.475  -38.510 1.00 30.49  ? 147 SER C N   1 
ATOM   8052  C  CA  . SER C 1 147 ? -5.130  44.979  -37.144 1.00 26.79  ? 147 SER C CA  1 
ATOM   8053  C  C   . SER C 1 147 ? -6.113  43.833  -36.938 1.00 21.37  ? 147 SER C C   1 
ATOM   8054  O  O   . SER C 1 147 ? -7.250  43.876  -37.410 1.00 24.24  ? 147 SER C O   1 
ATOM   8055  C  CB  . SER C 1 147 ? -5.418  46.103  -36.150 1.00 28.55  ? 147 SER C CB  1 
ATOM   8056  O  OG  . SER C 1 147 ? -5.488  45.574  -34.849 1.00 30.08  ? 147 SER C OG  1 
ATOM   8057  N  N   . LEU C 1 148 ? -5.680  42.799  -36.221 1.00 25.48  ? 148 LEU C N   1 
ATOM   8058  C  CA  . LEU C 1 148 ? -6.627  41.762  -35.833 1.00 23.78  ? 148 LEU C CA  1 
ATOM   8059  C  C   . LEU C 1 148 ? -7.718  42.303  -34.904 1.00 23.68  ? 148 LEU C C   1 
ATOM   8060  O  O   . LEU C 1 148 ? -8.767  41.662  -34.771 1.00 25.41  ? 148 LEU C O   1 
ATOM   8061  C  CB  . LEU C 1 148 ? -5.875  40.585  -35.198 1.00 23.86  ? 148 LEU C CB  1 
ATOM   8062  C  CG  . LEU C 1 148 ? -5.023  39.752  -36.150 1.00 21.31  ? 148 LEU C CG  1 
ATOM   8063  C  CD1 . LEU C 1 148 ? -4.528  38.479  -35.499 1.00 30.10  ? 148 LEU C CD1 1 
ATOM   8064  C  CD2 . LEU C 1 148 ? -5.767  39.440  -37.403 1.00 19.70  ? 148 LEU C CD2 1 
ATOM   8065  N  N   . TYR C 1 149 ? -7.510  43.483  -34.284 1.00 25.55  ? 149 TYR C N   1 
ATOM   8066  C  CA  . TYR C 1 149 ? -8.601  44.196  -33.601 1.00 26.65  ? 149 TYR C CA  1 
ATOM   8067  C  C   . TYR C 1 149 ? -9.827  44.312  -34.492 1.00 26.52  ? 149 TYR C C   1 
ATOM   8068  O  O   . TYR C 1 149 ? -10.957 44.274  -34.000 1.00 29.08  ? 149 TYR C O   1 
ATOM   8069  C  CB  . TYR C 1 149 ? -8.130  45.600  -33.140 1.00 25.40  ? 149 TYR C CB  1 
ATOM   8070  C  CG  . TYR C 1 149 ? -9.174  46.523  -32.491 1.00 29.73  ? 149 TYR C CG  1 
ATOM   8071  C  CD1 . TYR C 1 149 ? -10.319 46.944  -33.168 1.00 37.57  ? 149 TYR C CD1 1 
ATOM   8072  C  CD2 . TYR C 1 149 ? -9.013  46.959  -31.181 1.00 45.34  ? 149 TYR C CD2 1 
ATOM   8073  C  CE1 . TYR C 1 149 ? -11.261 47.763  -32.579 1.00 35.44  ? 149 TYR C CE1 1 
ATOM   8074  C  CE2 . TYR C 1 149 ? -9.953  47.787  -30.574 1.00 43.91  ? 149 TYR C CE2 1 
ATOM   8075  C  CZ  . TYR C 1 149 ? -11.071 48.179  -31.278 1.00 46.28  ? 149 TYR C CZ  1 
ATOM   8076  O  OH  . TYR C 1 149 ? -11.999 48.986  -30.677 1.00 52.69  ? 149 TYR C OH  1 
ATOM   8077  N  N   . SER C 1 150 ? -9.632  44.459  -35.807 1.00 25.44  ? 150 SER C N   1 
ATOM   8078  C  CA  . SER C 1 150 ? -10.774 44.569  -36.704 1.00 26.99  ? 150 SER C CA  1 
ATOM   8079  C  C   . SER C 1 150 ? -11.695 43.364  -36.581 1.00 27.82  ? 150 SER C C   1 
ATOM   8080  O  O   . SER C 1 150 ? -12.899 43.485  -36.832 1.00 28.50  ? 150 SER C O   1 
ATOM   8081  C  CB  . SER C 1 150 ? -10.300 44.734  -38.154 1.00 27.95  ? 150 SER C CB  1 
ATOM   8082  O  OG  . SER C 1 150 ? -9.609  45.966  -38.336 1.00 28.86  ? 150 SER C OG  1 
ATOM   8083  N  N   . TYR C 1 151 ? -11.165 42.211  -36.163 1.00 24.78  ? 151 TYR C N   1 
ATOM   8084  C  CA  . TYR C 1 151 ? -11.933 40.970  -36.095 1.00 26.52  ? 151 TYR C CA  1 
ATOM   8085  C  C   . TYR C 1 151 ? -12.320 40.581  -34.669 1.00 26.63  ? 151 TYR C C   1 
ATOM   8086  O  O   . TYR C 1 151 ? -12.450 39.386  -34.369 1.00 27.23  ? 151 TYR C O   1 
ATOM   8087  C  CB  . TYR C 1 151 ? -11.150 39.824  -36.738 1.00 30.18  ? 151 TYR C CB  1 
ATOM   8088  C  CG  . TYR C 1 151 ? -10.764 40.032  -38.192 1.00 30.36  ? 151 TYR C CG  1 
ATOM   8089  C  CD1 . TYR C 1 151 ? -11.673 40.578  -39.109 1.00 26.34  ? 151 TYR C CD1 1 
ATOM   8090  C  CD2 . TYR C 1 151 ? -9.500  39.658  -38.656 1.00 23.72  ? 151 TYR C CD2 1 
ATOM   8091  C  CE1 . TYR C 1 151 ? -11.331 40.742  -40.437 1.00 26.89  ? 151 TYR C CE1 1 
ATOM   8092  C  CE2 . TYR C 1 151 ? -9.153  39.823  -39.986 1.00 26.14  ? 151 TYR C CE2 1 
ATOM   8093  C  CZ  . TYR C 1 151 ? -10.068 40.364  -40.866 1.00 29.39  ? 151 TYR C CZ  1 
ATOM   8094  O  OH  . TYR C 1 151 ? -9.715  40.527  -42.176 1.00 26.29  ? 151 TYR C OH  1 
ATOM   8095  N  N   . MET C 1 152 ? -12.491 41.559  -33.785 1.00 29.87  ? 152 MET C N   1 
ATOM   8096  C  CA  . MET C 1 152 ? -12.852 41.276  -32.405 1.00 26.40  ? 152 MET C CA  1 
ATOM   8097  C  C   . MET C 1 152 ? -14.240 40.643  -32.338 1.00 26.63  ? 152 MET C C   1 
ATOM   8098  O  O   . MET C 1 152 ? -15.126 40.967  -33.136 1.00 25.76  ? 152 MET C O   1 
ATOM   8099  C  CB  . MET C 1 152 ? -12.811 42.567  -31.573 1.00 30.72  ? 152 MET C CB  1 
ATOM   8100  C  CG  . MET C 1 152 ? -13.818 42.594  -30.418 1.00 29.40  ? 152 MET C CG  1 
ATOM   8101  S  SD  . MET C 1 152 ? -14.048 44.205  -29.682 1.00 33.34  ? 152 MET C SD  1 
ATOM   8102  C  CE  . MET C 1 152 ? -14.880 43.662  -28.169 1.00 28.88  ? 152 MET C CE  1 
ATOM   8103  N  N   . SER C 1 153 ? -14.411 39.726  -31.368 1.00 25.79  ? 153 SER C N   1 
ATOM   8104  C  CA  . SER C 1 153 ? -15.554 38.825  -31.225 1.00 25.23  ? 153 SER C CA  1 
ATOM   8105  C  C   . SER C 1 153 ? -15.529 37.715  -32.288 1.00 31.60  ? 153 SER C C   1 
ATOM   8106  O  O   . SER C 1 153 ? -15.801 36.551  -31.970 1.00 31.90  ? 153 SER C O   1 
ATOM   8107  C  CB  . SER C 1 153 ? -16.881 39.586  -31.266 1.00 27.55  ? 153 SER C CB  1 
ATOM   8108  O  OG  . SER C 1 153 ? -16.835 40.736  -30.419 1.00 32.95  ? 153 SER C OG  1 
ATOM   8109  N  N   . ASP C 1 154 ? -15.196 38.031  -33.546 1.00 26.24  ? 154 ASP C N   1 
ATOM   8110  C  CA  . ASP C 1 154 ? -15.015 36.960  -34.534 1.00 28.19  ? 154 ASP C CA  1 
ATOM   8111  C  C   . ASP C 1 154 ? -13.814 36.095  -34.185 1.00 26.89  ? 154 ASP C C   1 
ATOM   8112  O  O   . ASP C 1 154 ? -13.865 34.866  -34.305 1.00 31.30  ? 154 ASP C O   1 
ATOM   8113  C  CB  . ASP C 1 154 ? -14.826 37.539  -35.939 1.00 23.72  ? 154 ASP C CB  1 
ATOM   8114  C  CG  . ASP C 1 154 ? -16.122 38.063  -36.523 1.00 32.21  ? 154 ASP C CG  1 
ATOM   8115  O  OD1 . ASP C 1 154 ? -17.166 37.438  -36.269 1.00 26.43  ? 154 ASP C OD1 1 
ATOM   8116  O  OD2 . ASP C 1 154 ? -16.096 39.113  -37.221 1.00 33.24  ? 154 ASP C OD2 1 
ATOM   8117  N  N   . TYR C 1 155 ? -12.722 36.724  -33.768 1.00 29.55  ? 155 TYR C N   1 
ATOM   8118  C  CA  . TYR C 1 155 ? -11.518 35.990  -33.431 1.00 28.16  ? 155 TYR C CA  1 
ATOM   8119  C  C   . TYR C 1 155 ? -11.784 35.132  -32.217 1.00 30.81  ? 155 TYR C C   1 
ATOM   8120  O  O   . TYR C 1 155 ? -12.065 35.659  -31.140 1.00 31.09  ? 155 TYR C O   1 
ATOM   8121  C  CB  . TYR C 1 155 ? -10.376 36.952  -33.151 1.00 27.59  ? 155 TYR C CB  1 
ATOM   8122  C  CG  . TYR C 1 155 ? -8.998  36.352  -33.310 1.00 29.25  ? 155 TYR C CG  1 
ATOM   8123  C  CD1 . TYR C 1 155 ? -8.393  36.299  -34.562 1.00 28.73  ? 155 TYR C CD1 1 
ATOM   8124  C  CD2 . TYR C 1 155 ? -8.315  35.810  -32.227 1.00 25.98  ? 155 TYR C CD2 1 
ATOM   8125  C  CE1 . TYR C 1 155 ? -7.134  35.768  -34.742 1.00 25.39  ? 155 TYR C CE1 1 
ATOM   8126  C  CE2 . TYR C 1 155 ? -7.027  35.253  -32.400 1.00 31.10  ? 155 TYR C CE2 1 
ATOM   8127  C  CZ  . TYR C 1 155 ? -6.457  35.244  -33.672 1.00 22.78  ? 155 TYR C CZ  1 
ATOM   8128  O  OH  . TYR C 1 155 ? -5.208  34.718  -33.905 1.00 24.53  ? 155 TYR C OH  1 
ATOM   8129  N  N   . GLY C 1 156 ? -11.710 33.814  -32.393 1.00 29.11  ? 156 GLY C N   1 
ATOM   8130  C  CA  . GLY C 1 156 ? -11.947 32.878  -31.321 1.00 24.22  ? 156 GLY C CA  1 
ATOM   8131  C  C   . GLY C 1 156 ? -13.343 32.295  -31.282 1.00 28.87  ? 156 GLY C C   1 
ATOM   8132  O  O   . GLY C 1 156 ? -13.574 31.353  -30.515 1.00 31.61  ? 156 GLY C O   1 
ATOM   8133  N  N   . THR C 1 157 ? -14.281 32.831  -32.068 1.00 28.83  ? 157 THR C N   1 
ATOM   8134  C  CA  . THR C 1 157 ? -15.597 32.231  -32.254 1.00 28.12  ? 157 THR C CA  1 
ATOM   8135  C  C   . THR C 1 157 ? -15.819 31.694  -33.665 1.00 30.12  ? 157 THR C C   1 
ATOM   8136  O  O   . THR C 1 157 ? -16.386 30.606  -33.822 1.00 28.31  ? 157 THR C O   1 
ATOM   8137  C  CB  . THR C 1 157 ? -16.700 33.250  -31.941 1.00 30.03  ? 157 THR C CB  1 
ATOM   8138  O  OG1 . THR C 1 157 ? -16.679 34.286  -32.924 1.00 27.96  ? 157 THR C OG1 1 
ATOM   8139  C  CG2 . THR C 1 157 ? -16.507 33.874  -30.551 1.00 27.98  ? 157 THR C CG2 1 
ATOM   8140  N  N   . VAL C 1 158 ? -15.399 32.445  -34.690 1.00 28.60  ? 158 VAL C N   1 
ATOM   8141  C  CA  . VAL C 1 158 ? -15.540 32.045  -36.087 1.00 26.71  ? 158 VAL C CA  1 
ATOM   8142  C  C   . VAL C 1 158 ? -14.232 32.143  -36.865 1.00 29.19  ? 158 VAL C C   1 
ATOM   8143  O  O   . VAL C 1 158 ? -14.201 31.792  -38.047 1.00 27.11  ? 158 VAL C O   1 
ATOM   8144  C  CB  . VAL C 1 158 ? -16.642 32.862  -36.814 1.00 27.97  ? 158 VAL C CB  1 
ATOM   8145  C  CG1 . VAL C 1 158 ? -17.890 33.035  -35.968 1.00 23.75  ? 158 VAL C CG1 1 
ATOM   8146  C  CG2 . VAL C 1 158 ? -16.115 34.229  -37.267 1.00 26.23  ? 158 VAL C CG2 1 
ATOM   8147  N  N   . MET C 1 159 ? -13.140 32.579  -36.244 1.00 24.38  ? 159 MET C N   1 
ATOM   8148  C  CA  . MET C 1 159 ? -11.918 32.884  -36.971 1.00 30.88  ? 159 MET C CA  1 
ATOM   8149  C  C   . MET C 1 159 ? -10.722 32.516  -36.102 1.00 32.52  ? 159 MET C C   1 
ATOM   8150  O  O   . MET C 1 159 ? -10.753 32.720  -34.888 1.00 31.58  ? 159 MET C O   1 
ATOM   8151  C  CB  . MET C 1 159 ? -11.863 34.378  -37.341 1.00 26.82  ? 159 MET C CB  1 
ATOM   8152  C  CG  . MET C 1 159 ? -10.593 34.791  -38.003 1.00 36.69  ? 159 MET C CG  1 
ATOM   8153  S  SD  . MET C 1 159 ? -10.628 36.511  -38.517 1.00 37.17  ? 159 MET C SD  1 
ATOM   8154  C  CE  . MET C 1 159 ? -12.190 36.551  -39.394 1.00 30.36  ? 159 MET C CE  1 
ATOM   8155  N  N   . ASP C 1 160 ? -9.682  31.978  -36.720 1.00 26.87  ? 160 ASP C N   1 
ATOM   8156  C  CA  . ASP C 1 160 ? -8.419  31.762  -36.041 1.00 20.22  ? 160 ASP C CA  1 
ATOM   8157  C  C   . ASP C 1 160 ? -7.324  32.575  -36.734 1.00 27.45  ? 160 ASP C C   1 
ATOM   8158  O  O   . ASP C 1 160 ? -7.576  33.334  -37.685 1.00 26.65  ? 160 ASP C O   1 
ATOM   8159  C  CB  . ASP C 1 160 ? -8.085  30.273  -35.978 1.00 24.64  ? 160 ASP C CB  1 
ATOM   8160  C  CG  . ASP C 1 160 ? -8.140  29.598  -37.336 1.00 29.05  ? 160 ASP C CG  1 
ATOM   8161  O  OD1 . ASP C 1 160 ? -8.246  30.296  -38.356 1.00 26.28  ? 160 ASP C OD1 1 
ATOM   8162  O  OD2 . ASP C 1 160 ? -8.052  28.355  -37.390 1.00 31.67  ? 160 ASP C OD2 1 
ATOM   8163  N  N   . LEU C 1 161 ? -6.103  32.442  -36.212 1.00 22.13  ? 161 LEU C N   1 
ATOM   8164  C  CA  . LEU C 1 161 ? -4.981  33.219  -36.716 1.00 23.45  ? 161 LEU C CA  1 
ATOM   8165  C  C   . LEU C 1 161 ? -4.835  33.072  -38.218 1.00 28.30  ? 161 LEU C C   1 
ATOM   8166  O  O   . LEU C 1 161 ? -4.774  34.067  -38.943 1.00 27.67  ? 161 LEU C O   1 
ATOM   8167  C  CB  . LEU C 1 161 ? -3.692  32.781  -36.042 1.00 25.63  ? 161 LEU C CB  1 
ATOM   8168  C  CG  . LEU C 1 161 ? -2.445  33.556  -36.461 1.00 22.88  ? 161 LEU C CG  1 
ATOM   8169  C  CD1 . LEU C 1 161 ? -2.634  35.044  -36.275 1.00 29.57  ? 161 LEU C CD1 1 
ATOM   8170  C  CD2 . LEU C 1 161 ? -1.257  33.088  -35.635 1.00 30.15  ? 161 LEU C CD2 1 
ATOM   8171  N  N   . GLU C 1 162 ? -4.764  31.825  -38.701 1.00 26.77  ? 162 GLU C N   1 
ATOM   8172  C  CA  . GLU C 1 162 ? -4.490  31.610  -40.115 1.00 30.81  ? 162 GLU C CA  1 
ATOM   8173  C  C   . GLU C 1 162 ? -5.623  32.129  -40.990 1.00 30.30  ? 162 GLU C C   1 
ATOM   8174  O  O   . GLU C 1 162 ? -5.366  32.755  -42.018 1.00 25.01  ? 162 GLU C O   1 
ATOM   8175  C  CB  . GLU C 1 162 ? -4.236  30.132  -40.416 1.00 29.02  ? 162 GLU C CB  1 
ATOM   8176  C  CG  . GLU C 1 162 ? -3.710  29.987  -41.852 1.00 33.97  ? 162 GLU C CG  1 
ATOM   8177  C  CD  . GLU C 1 162 ? -3.489  28.557  -42.297 1.00 36.27  ? 162 GLU C CD  1 
ATOM   8178  O  OE1 . GLU C 1 162 ? -3.825  27.631  -41.531 1.00 34.51  ? 162 GLU C OE1 1 
ATOM   8179  O  OE2 . GLU C 1 162 ? -3.009  28.375  -43.445 1.00 35.51  ? 162 GLU C OE2 1 
ATOM   8180  N  N   . THR C 1 163 ? -6.880  31.867  -40.606 1.00 23.83  ? 163 THR C N   1 
ATOM   8181  C  CA  . THR C 1 163 ? -8.009  32.398  -41.364 1.00 23.50  ? 163 THR C CA  1 
ATOM   8182  C  C   . THR C 1 163 ? -7.936  33.923  -41.476 1.00 28.24  ? 163 THR C C   1 
ATOM   8183  O  O   . THR C 1 163 ? -8.190  34.488  -42.548 1.00 32.58  ? 163 THR C O   1 
ATOM   8184  C  CB  . THR C 1 163 ? -9.327  31.953  -40.713 1.00 24.63  ? 163 THR C CB  1 
ATOM   8185  O  OG1 . THR C 1 163 ? -9.353  30.515  -40.585 1.00 23.43  ? 163 THR C OG1 1 
ATOM   8186  C  CG2 . THR C 1 163 ? -10.510 32.412  -41.535 1.00 23.45  ? 163 THR C CG2 1 
ATOM   8187  N  N   . ALA C 1 164 ? -7.551  34.608  -40.391 1.00 28.24  ? 164 ALA C N   1 
ATOM   8188  C  CA  . ALA C 1 164 ? -7.440  36.067  -40.433 1.00 29.96  ? 164 ALA C CA  1 
ATOM   8189  C  C   . ALA C 1 164 ? -6.303  36.508  -41.355 1.00 28.30  ? 164 ALA C C   1 
ATOM   8190  O  O   . ALA C 1 164 ? -6.465  37.424  -42.173 1.00 25.61  ? 164 ALA C O   1 
ATOM   8191  C  CB  . ALA C 1 164 ? -7.234  36.614  -39.015 1.00 22.35  ? 164 ALA C CB  1 
ATOM   8192  N  N   . MET C 1 165 ? -5.156  35.847  -41.244 1.00 27.82  ? 165 MET C N   1 
ATOM   8193  C  CA  . MET C 1 165 ? -4.013  36.156  -42.094 1.00 26.40  ? 165 MET C CA  1 
ATOM   8194  C  C   . MET C 1 165 ? -4.364  35.984  -43.568 1.00 27.11  ? 165 MET C C   1 
ATOM   8195  O  O   . MET C 1 165 ? -4.025  36.840  -44.394 1.00 28.90  ? 165 MET C O   1 
ATOM   8196  C  CB  . MET C 1 165 ? -2.836  35.262  -41.695 1.00 30.28  ? 165 MET C CB  1 
ATOM   8197  C  CG  . MET C 1 165 ? -1.865  35.979  -40.787 1.00 32.75  ? 165 MET C CG  1 
ATOM   8198  S  SD  . MET C 1 165 ? -0.249  35.266  -40.570 1.00 32.83  ? 165 MET C SD  1 
ATOM   8199  C  CE  . MET C 1 165 ? -0.195  35.254  -38.791 1.00 31.19  ? 165 MET C CE  1 
ATOM   8200  N  N   . ALA C 1 166 ? -5.062  34.903  -43.918 1.00 25.82  ? 166 ALA C N   1 
ATOM   8201  C  CA  . ALA C 1 166 ? -5.479  34.726  -45.312 1.00 27.61  ? 166 ALA C CA  1 
ATOM   8202  C  C   . ALA C 1 166 ? -6.350  35.882  -45.775 1.00 30.03  ? 166 ALA C C   1 
ATOM   8203  O  O   . ALA C 1 166 ? -6.238  36.341  -46.923 1.00 25.27  ? 166 ALA C O   1 
ATOM   8204  C  CB  . ALA C 1 166 ? -6.232  33.413  -45.494 1.00 26.39  ? 166 ALA C CB  1 
ATOM   8205  N  N   . SER C 1 167 ? -7.225  36.368  -44.892 1.00 29.32  ? 167 SER C N   1 
ATOM   8206  C  CA  . SER C 1 167 ? -8.122  37.437  -45.287 1.00 26.83  ? 167 SER C CA  1 
ATOM   8207  C  C   . SER C 1 167 ? -7.343  38.717  -45.548 1.00 26.69  ? 167 SER C C   1 
ATOM   8208  O  O   . SER C 1 167 ? -7.725  39.507  -46.417 1.00 26.37  ? 167 SER C O   1 
ATOM   8209  C  CB  . SER C 1 167 ? -9.195  37.638  -44.210 1.00 30.53  ? 167 SER C CB  1 
ATOM   8210  O  OG  . SER C 1 167 ? -8.689  38.330  -43.072 1.00 27.40  ? 167 SER C OG  1 
ATOM   8211  N  N   . ILE C 1 168 ? -6.243  38.917  -44.820 1.00 26.18  ? 168 ILE C N   1 
ATOM   8212  C  CA  . ILE C 1 168 ? -5.434  40.123  -44.940 1.00 27.43  ? 168 ILE C CA  1 
ATOM   8213  C  C   . ILE C 1 168 ? -4.579  40.075  -46.196 1.00 30.46  ? 168 ILE C C   1 
ATOM   8214  O  O   . ILE C 1 168 ? -4.475  41.064  -46.934 1.00 32.14  ? 168 ILE C O   1 
ATOM   8215  C  CB  . ILE C 1 168 ? -4.549  40.296  -43.693 1.00 27.82  ? 168 ILE C CB  1 
ATOM   8216  C  CG1 . ILE C 1 168 ? -5.395  40.465  -42.434 1.00 29.57  ? 168 ILE C CG1 1 
ATOM   8217  C  CG2 . ILE C 1 168 ? -3.633  41.453  -43.880 1.00 23.94  ? 168 ILE C CG2 1 
ATOM   8218  C  CD1 . ILE C 1 168 ? -4.593  40.271  -41.140 1.00 32.59  ? 168 ILE C CD1 1 
ATOM   8219  N  N   . ALA C 1 169 ? -3.919  38.939  -46.427 1.00 26.78  ? 169 ALA C N   1 
ATOM   8220  C  CA  . ALA C 1 169 ? -3.155  38.739  -47.654 1.00 30.37  ? 169 ALA C CA  1 
ATOM   8221  C  C   . ALA C 1 169 ? -4.032  38.974  -48.879 1.00 29.36  ? 169 ALA C C   1 
ATOM   8222  O  O   . ALA C 1 169 ? -3.659  39.713  -49.794 1.00 29.64  ? 169 ALA C O   1 
ATOM   8223  C  CB  . ALA C 1 169 ? -2.558  37.324  -47.675 1.00 29.08  ? 169 ALA C CB  1 
ATOM   8224  N  N   . ASP C 1 170 ? -5.237  38.401  -48.874 1.00 27.58  ? 170 ASP C N   1 
ATOM   8225  C  CA  . ASP C 1 170 ? -6.137  38.509  -50.017 1.00 32.76  ? 170 ASP C CA  1 
ATOM   8226  C  C   . ASP C 1 170 ? -6.485  39.958  -50.346 1.00 31.50  ? 170 ASP C C   1 
ATOM   8227  O  O   . ASP C 1 170 ? -6.885  40.253  -51.480 1.00 30.88  ? 170 ASP C O   1 
ATOM   8228  C  CB  . ASP C 1 170 ? -7.413  37.701  -49.733 1.00 24.62  ? 170 ASP C CB  1 
ATOM   8229  C  CG  . ASP C 1 170 ? -8.216  37.398  -50.989 1.00 29.21  ? 170 ASP C CG  1 
ATOM   8230  O  OD1 . ASP C 1 170 ? -7.767  36.572  -51.820 1.00 29.76  ? 170 ASP C OD1 1 
ATOM   8231  O  OD2 . ASP C 1 170 ? -9.320  37.981  -51.135 1.00 29.28  ? 170 ASP C OD2 1 
ATOM   8232  N  N   . LEU C 1 171 ? -6.349  40.862  -49.379 1.00 29.36  ? 171 LEU C N   1 
ATOM   8233  C  CA  . LEU C 1 171 ? -6.627  42.278  -49.570 1.00 31.90  ? 171 LEU C CA  1 
ATOM   8234  C  C   . LEU C 1 171 ? -5.505  43.014  -50.286 1.00 31.24  ? 171 LEU C C   1 
ATOM   8235  O  O   . LEU C 1 171 ? -5.643  44.209  -50.551 1.00 34.21  ? 171 LEU C O   1 
ATOM   8236  C  CB  . LEU C 1 171 ? -6.889  42.933  -48.203 1.00 33.54  ? 171 LEU C CB  1 
ATOM   8237  C  CG  . LEU C 1 171 ? -8.342  42.757  -47.812 1.00 28.78  ? 171 LEU C CG  1 
ATOM   8238  C  CD1 . LEU C 1 171 ? -8.626  43.335  -46.452 1.00 30.67  ? 171 LEU C CD1 1 
ATOM   8239  C  CD2 . LEU C 1 171 ? -9.149  43.469  -48.871 1.00 33.71  ? 171 LEU C CD2 1 
ATOM   8240  N  N   . GLY C 1 172 ? -4.403  42.344  -50.601 1.00 32.94  ? 172 GLY C N   1 
ATOM   8241  C  CA  . GLY C 1 172 ? -3.225  43.085  -50.996 1.00 34.11  ? 172 GLY C CA  1 
ATOM   8242  C  C   . GLY C 1 172 ? -2.519  43.776  -49.856 1.00 33.18  ? 172 GLY C C   1 
ATOM   8243  O  O   . GLY C 1 172 ? -1.556  44.502  -50.090 1.00 30.68  ? 172 GLY C O   1 
ATOM   8244  N  N   . ALA C 1 173 ? -2.959  43.571  -48.618 1.00 34.52  ? 173 ALA C N   1 
ATOM   8245  C  CA  . ALA C 1 173 ? -2.298  44.213  -47.496 1.00 28.32  ? 173 ALA C CA  1 
ATOM   8246  C  C   . ALA C 1 173 ? -1.002  43.490  -47.183 1.00 25.34  ? 173 ALA C C   1 
ATOM   8247  O  O   . ALA C 1 173 ? -0.881  42.281  -47.373 1.00 32.22  ? 173 ALA C O   1 
ATOM   8248  C  CB  . ALA C 1 173 ? -3.207  44.225  -46.267 1.00 29.25  ? 173 ALA C CB  1 
ATOM   8249  N  N   . THR C 1 174 ? -0.037  44.235  -46.682 1.00 24.73  ? 174 THR C N   1 
ATOM   8250  C  CA  . THR C 1 174 ? 1.269   43.690  -46.360 1.00 30.09  ? 174 THR C CA  1 
ATOM   8251  C  C   . THR C 1 174 ? 1.548   43.624  -44.868 1.00 26.50  ? 174 THR C C   1 
ATOM   8252  O  O   . THR C 1 174 ? 2.510   42.951  -44.470 1.00 27.04  ? 174 THR C O   1 
ATOM   8253  C  CB  . THR C 1 174 ? 2.387   44.526  -47.019 1.00 28.80  ? 174 THR C CB  1 
ATOM   8254  O  OG1 . THR C 1 174 ? 2.276   45.904  -46.619 1.00 26.66  ? 174 THR C OG1 1 
ATOM   8255  C  CG2 . THR C 1 174 ? 2.352   44.396  -48.545 1.00 28.23  ? 174 THR C CG2 1 
ATOM   8256  N  N   . GLY C 1 175 ? 0.775   44.336  -44.052 1.00 29.19  ? 175 GLY C N   1 
ATOM   8257  C  CA  . GLY C 1 175 ? 1.049   44.467  -42.628 1.00 25.74  ? 175 GLY C CA  1 
ATOM   8258  C  C   . GLY C 1 175 ? -0.056  43.840  -41.793 1.00 23.56  ? 175 GLY C C   1 
ATOM   8259  O  O   . GLY C 1 175 ? -1.241  43.971  -42.110 1.00 25.96  ? 175 GLY C O   1 
ATOM   8260  N  N   . ILE C 1 176 ? 0.343   43.144  -40.738 1.00 23.57  ? 176 ILE C N   1 
ATOM   8261  C  CA  . ILE C 1 176 ? -0.590  42.609  -39.755 1.00 28.20  ? 176 ILE C CA  1 
ATOM   8262  C  C   . ILE C 1 176 ? -0.280  43.287  -38.419 1.00 26.19  ? 176 ILE C C   1 
ATOM   8263  O  O   . ILE C 1 176 ? 0.874   43.298  -37.974 1.00 24.85  ? 176 ILE C O   1 
ATOM   8264  C  CB  . ILE C 1 176 ? -0.488  41.084  -39.658 1.00 24.81  ? 176 ILE C CB  1 
ATOM   8265  C  CG1 . ILE C 1 176 ? -1.363  40.554  -38.524 1.00 26.58  ? 176 ILE C CG1 1 
ATOM   8266  C  CG2 . ILE C 1 176 ? 0.954   40.661  -39.430 1.00 23.09  ? 176 ILE C CG2 1 
ATOM   8267  C  CD1 . ILE C 1 176 ? -1.850  39.131  -38.785 1.00 24.58  ? 176 ILE C CD1 1 
ATOM   8268  N  N   . GLU C 1 177 ? -1.290  43.890  -37.806 1.00 27.15  ? 177 GLU C N   1 
ATOM   8269  C  CA  . GLU C 1 177 ? -1.162  44.466  -36.475 1.00 25.63  ? 177 GLU C CA  1 
ATOM   8270  C  C   . GLU C 1 177 ? -1.949  43.578  -35.513 1.00 27.48  ? 177 GLU C C   1 
ATOM   8271  O  O   . GLU C 1 177 ? -3.003  43.052  -35.871 1.00 24.63  ? 177 GLU C O   1 
ATOM   8272  C  CB  . GLU C 1 177 ? -1.655  45.926  -36.458 1.00 24.18  ? 177 GLU C CB  1 
ATOM   8273  C  CG  . GLU C 1 177 ? -1.857  46.580  -35.087 1.00 28.94  ? 177 GLU C CG  1 
ATOM   8274  C  CD  . GLU C 1 177 ? -2.330  48.025  -35.156 1.00 28.39  ? 177 GLU C CD  1 
ATOM   8275  O  OE1 . GLU C 1 177 ? -2.866  48.457  -36.204 1.00 33.12  ? 177 GLU C OE1 1 
ATOM   8276  O  OE2 . GLU C 1 177 ? -2.183  48.745  -34.154 1.00 30.69  ? 177 GLU C OE2 1 
ATOM   8277  N  N   . ILE C 1 178 ? -1.416  43.353  -34.314 1.00 26.80  ? 178 ILE C N   1 
ATOM   8278  C  CA  . ILE C 1 178 ? -2.094  42.520  -33.326 1.00 24.10  ? 178 ILE C CA  1 
ATOM   8279  C  C   . ILE C 1 178 ? -2.109  43.262  -31.996 1.00 28.02  ? 178 ILE C C   1 
ATOM   8280  O  O   . ILE C 1 178 ? -1.514  44.327  -31.844 1.00 28.11  ? 178 ILE C O   1 
ATOM   8281  C  CB  . ILE C 1 178 ? -1.459  41.120  -33.162 1.00 23.16  ? 178 ILE C CB  1 
ATOM   8282  C  CG1 . ILE C 1 178 ? -0.154  41.177  -32.362 1.00 28.42  ? 178 ILE C CG1 1 
ATOM   8283  C  CG2 . ILE C 1 178 ? -1.224  40.435  -34.502 1.00 26.10  ? 178 ILE C CG2 1 
ATOM   8284  C  CD1 . ILE C 1 178 ? 0.405   39.805  -32.084 1.00 23.96  ? 178 ILE C CD1 1 
ATOM   8285  N  N   . LEU C 1 179 ? -2.855  42.696  -31.050 1.00 29.77  ? 179 LEU C N   1 
ATOM   8286  C  CA  . LEU C 1 179 ? -2.854  43.092  -29.648 1.00 25.78  ? 179 LEU C CA  1 
ATOM   8287  C  C   . LEU C 1 179 ? -2.230  41.940  -28.875 1.00 23.22  ? 179 LEU C C   1 
ATOM   8288  O  O   . LEU C 1 179 ? -2.824  40.863  -28.790 1.00 31.38  ? 179 LEU C O   1 
ATOM   8289  C  CB  . LEU C 1 179 ? -4.273  43.367  -29.150 1.00 29.21  ? 179 LEU C CB  1 
ATOM   8290  C  CG  . LEU C 1 179 ? -5.143  44.448  -29.797 1.00 24.89  ? 179 LEU C CG  1 
ATOM   8291  C  CD1 . LEU C 1 179 ? -6.456  44.584  -29.027 1.00 25.74  ? 179 LEU C CD1 1 
ATOM   8292  C  CD2 . LEU C 1 179 ? -4.402  45.773  -29.834 1.00 21.05  ? 179 LEU C CD2 1 
ATOM   8293  N  N   . GLY C 1 180 ? -1.046  42.174  -28.312 1.00 24.04  ? 180 GLY C N   1 
ATOM   8294  C  CA  . GLY C 1 180 ? -0.312  41.108  -27.639 1.00 31.03  ? 180 GLY C CA  1 
ATOM   8295  C  C   . GLY C 1 180 ? -1.150  40.321  -26.644 1.00 30.95  ? 180 GLY C C   1 
ATOM   8296  O  O   . GLY C 1 180 ? -1.259  39.101  -26.741 1.00 22.24  ? 180 GLY C O   1 
ATOM   8297  N  N   . GLU C 1 181 ? -1.774  41.012  -25.684 1.00 28.84  ? 181 GLU C N   1 
ATOM   8298  C  CA  . GLU C 1 181 ? -2.615  40.302  -24.716 1.00 30.30  ? 181 GLU C CA  1 
ATOM   8299  C  C   . GLU C 1 181 ? -3.888  39.725  -25.334 1.00 28.90  ? 181 GLU C C   1 
ATOM   8300  O  O   . GLU C 1 181 ? -4.683  39.102  -24.615 1.00 30.24  ? 181 GLU C O   1 
ATOM   8301  C  CB  . GLU C 1 181 ? -2.983  41.231  -23.553 1.00 26.66  ? 181 GLU C CB  1 
ATOM   8302  C  CG  . GLU C 1 181 ? -1.778  41.689  -22.749 1.00 28.80  ? 181 GLU C CG  1 
ATOM   8303  C  CD  . GLU C 1 181 ? -2.161  42.491  -21.530 1.00 30.42  ? 181 GLU C CD  1 
ATOM   8304  O  OE1 . GLU C 1 181 ? -3.083  42.038  -20.804 1.00 30.34  ? 181 GLU C OE1 1 
ATOM   8305  O  OE2 . GLU C 1 181 ? -1.539  43.559  -21.286 1.00 31.13  ? 181 GLU C OE2 1 
ATOM   8306  N  N   . ALA C 1 182 ? -4.121  39.918  -26.631 1.00 28.38  ? 182 ALA C N   1 
ATOM   8307  C  CA  . ALA C 1 182 ? -5.279  39.316  -27.275 1.00 23.62  ? 182 ALA C CA  1 
ATOM   8308  C  C   . ALA C 1 182 ? -4.898  38.123  -28.132 1.00 29.24  ? 182 ALA C C   1 
ATOM   8309  O  O   . ALA C 1 182 ? -5.507  37.058  -28.025 1.00 30.71  ? 182 ALA C O   1 
ATOM   8310  C  CB  . ALA C 1 182 ? -6.005  40.342  -28.142 1.00 26.57  ? 182 ALA C CB  1 
ATOM   8311  N  N   . HIS C 1 183 ? -3.891  38.281  -28.979 1.00 27.11  ? 183 HIS C N   1 
ATOM   8312  C  CA  . HIS C 1 183 ? -3.659  37.344  -30.060 1.00 23.88  ? 183 HIS C CA  1 
ATOM   8313  C  C   . HIS C 1 183 ? -2.447  36.473  -29.842 1.00 23.55  ? 183 HIS C C   1 
ATOM   8314  O  O   . HIS C 1 183 ? -2.130  35.663  -30.718 1.00 26.92  ? 183 HIS C O   1 
ATOM   8315  C  CB  . HIS C 1 183 ? -3.525  38.110  -31.370 1.00 23.51  ? 183 HIS C CB  1 
ATOM   8316  C  CG  . HIS C 1 183 ? -4.643  39.073  -31.598 1.00 24.02  ? 183 HIS C CG  1 
ATOM   8317  N  ND1 . HIS C 1 183 ? -4.487  40.435  -31.498 1.00 24.57  ? 183 HIS C ND1 1 
ATOM   8318  C  CD2 . HIS C 1 183 ? -5.949  38.861  -31.875 1.00 26.34  ? 183 HIS C CD2 1 
ATOM   8319  C  CE1 . HIS C 1 183 ? -5.646  41.024  -31.726 1.00 23.11  ? 183 HIS C CE1 1 
ATOM   8320  N  NE2 . HIS C 1 183 ? -6.549  40.088  -31.951 1.00 27.12  ? 183 HIS C NE2 1 
ATOM   8321  N  N   . VAL C 1 184 ? -1.779  36.594  -28.699 1.00 23.33  ? 184 VAL C N   1 
ATOM   8322  C  CA  . VAL C 1 184 ? -0.630  35.757  -28.369 1.00 30.18  ? 184 VAL C CA  1 
ATOM   8323  C  C   . VAL C 1 184 ? -1.106  34.700  -27.371 1.00 22.56  ? 184 VAL C C   1 
ATOM   8324  O  O   . VAL C 1 184 ? -1.342  35.037  -26.196 1.00 26.79  ? 184 VAL C O   1 
ATOM   8325  C  CB  . VAL C 1 184 ? 0.538   36.578  -27.801 1.00 24.90  ? 184 VAL C CB  1 
ATOM   8326  C  CG1 . VAL C 1 184 ? 1.688   35.661  -27.383 1.00 25.67  ? 184 VAL C CG1 1 
ATOM   8327  C  CG2 . VAL C 1 184 ? 1.030   37.585  -28.812 1.00 28.30  ? 184 VAL C CG2 1 
ATOM   8328  N  N   . PRO C 1 185 ? -1.275  33.452  -27.782 1.00 20.74  ? 185 PRO C N   1 
ATOM   8329  C  CA  . PRO C 1 185 ? -1.756  32.424  -26.845 1.00 25.73  ? 185 PRO C CA  1 
ATOM   8330  C  C   . PRO C 1 185 ? -0.737  32.166  -25.743 1.00 30.19  ? 185 PRO C C   1 
ATOM   8331  O  O   . PRO C 1 185 ? 0.473   32.224  -25.966 1.00 28.56  ? 185 PRO C O   1 
ATOM   8332  C  CB  . PRO C 1 185 ? -1.957  31.193  -27.735 1.00 28.62  ? 185 PRO C CB  1 
ATOM   8333  C  CG  . PRO C 1 185 ? -2.056  31.750  -29.139 1.00 25.06  ? 185 PRO C CG  1 
ATOM   8334  C  CD  . PRO C 1 185 ? -1.110  32.922  -29.143 1.00 26.92  ? 185 PRO C CD  1 
ATOM   8335  N  N   . ASN C 1 186 ? -1.248  31.924  -24.532 1.00 30.82  ? 186 ASN C N   1 
ATOM   8336  C  CA  . ASN C 1 186 ? -0.435  31.803  -23.322 1.00 28.01  ? 186 ASN C CA  1 
ATOM   8337  C  C   . ASN C 1 186 ? 0.442   33.029  -23.078 1.00 28.72  ? 186 ASN C C   1 
ATOM   8338  O  O   . ASN C 1 186 ? 1.536   32.907  -22.517 1.00 27.98  ? 186 ASN C O   1 
ATOM   8339  C  CB  . ASN C 1 186 ? 0.425   30.532  -23.320 1.00 32.18  ? 186 ASN C CB  1 
ATOM   8340  C  CG  . ASN C 1 186 ? 0.833   30.130  -21.894 1.00 36.34  ? 186 ASN C CG  1 
ATOM   8341  O  OD1 . ASN C 1 186 ? 0.021   30.244  -20.977 1.00 28.10  ? 186 ASN C OD1 1 
ATOM   8342  N  ND2 . ASN C 1 186 ? 2.096   29.716  -21.697 1.00 29.41  ? 186 ASN C ND2 1 
ATOM   8343  N  N   . TYR C 1 187 ? -0.038  34.214  -23.468 1.00 27.16  ? 187 TYR C N   1 
ATOM   8344  C  CA  . TYR C 1 187 ? 0.643   35.455  -23.113 1.00 27.95  ? 187 TYR C CA  1 
ATOM   8345  C  C   . TYR C 1 187 ? 0.970   35.461  -21.621 1.00 25.64  ? 187 TYR C C   1 
ATOM   8346  O  O   . TYR C 1 187 ? 0.123   35.083  -20.808 1.00 28.97  ? 187 TYR C O   1 
ATOM   8347  C  CB  . TYR C 1 187 ? -0.226  36.673  -23.464 1.00 29.75  ? 187 TYR C CB  1 
ATOM   8348  C  CG  . TYR C 1 187 ? 0.376   38.024  -23.055 1.00 31.31  ? 187 TYR C CG  1 
ATOM   8349  C  CD1 . TYR C 1 187 ? 0.305   38.467  -21.740 1.00 25.34  ? 187 TYR C CD1 1 
ATOM   8350  C  CD2 . TYR C 1 187 ? 1.018   38.844  -23.989 1.00 24.99  ? 187 TYR C CD2 1 
ATOM   8351  C  CE1 . TYR C 1 187 ? 0.843   39.671  -21.345 1.00 28.49  ? 187 TYR C CE1 1 
ATOM   8352  C  CE2 . TYR C 1 187 ? 1.564   40.076  -23.605 1.00 27.25  ? 187 TYR C CE2 1 
ATOM   8353  C  CZ  . TYR C 1 187 ? 1.472   40.473  -22.270 1.00 28.62  ? 187 TYR C CZ  1 
ATOM   8354  O  OH  . TYR C 1 187 ? 1.984   41.665  -21.844 1.00 28.04  ? 187 TYR C OH  1 
ATOM   8355  N  N   . PRO C 1 188 ? 2.177   35.892  -21.222 1.00 28.39  ? 188 PRO C N   1 
ATOM   8356  C  CA  . PRO C 1 188 ? 3.217   36.435  -22.117 1.00 28.47  ? 188 PRO C CA  1 
ATOM   8357  C  C   . PRO C 1 188 ? 4.219   35.393  -22.619 1.00 27.86  ? 188 PRO C C   1 
ATOM   8358  O  O   . PRO C 1 188 ? 5.292   35.776  -23.100 1.00 29.05  ? 188 PRO C O   1 
ATOM   8359  C  CB  . PRO C 1 188 ? 3.920   37.492  -21.231 1.00 23.33  ? 188 PRO C CB  1 
ATOM   8360  C  CG  . PRO C 1 188 ? 3.857   36.872  -19.823 1.00 32.16  ? 188 PRO C CG  1 
ATOM   8361  C  CD  . PRO C 1 188 ? 2.539   36.041  -19.793 1.00 30.43  ? 188 PRO C CD  1 
ATOM   8362  N  N   . ASN C 1 189 ? 3.866   34.109  -22.559 1.00 28.89  ? 189 ASN C N   1 
ATOM   8363  C  CA  . ASN C 1 189 ? 4.802   33.009  -22.801 1.00 27.09  ? 189 ASN C CA  1 
ATOM   8364  C  C   . ASN C 1 189 ? 4.348   32.102  -23.943 1.00 26.40  ? 189 ASN C C   1 
ATOM   8365  O  O   . ASN C 1 189 ? 4.100   30.907  -23.734 1.00 27.41  ? 189 ASN C O   1 
ATOM   8366  C  CB  . ASN C 1 189 ? 4.996   32.172  -21.533 1.00 26.69  ? 189 ASN C CB  1 
ATOM   8367  C  CG  . ASN C 1 189 ? 5.500   32.984  -20.354 1.00 28.86  ? 189 ASN C CG  1 
ATOM   8368  O  OD1 . ASN C 1 189 ? 6.414   33.806  -20.473 1.00 26.44  ? 189 ASN C OD1 1 
ATOM   8369  N  ND2 . ASN C 1 189 ? 4.920   32.731  -19.193 1.00 30.98  ? 189 ASN C ND2 1 
ATOM   8370  N  N   . PRO C 1 190 ? 4.263   32.614  -25.166 1.00 28.24  ? 190 PRO C N   1 
ATOM   8371  C  CA  . PRO C 1 190 ? 3.828   31.754  -26.267 1.00 25.89  ? 190 PRO C CA  1 
ATOM   8372  C  C   . PRO C 1 190 ? 4.822   30.619  -26.428 1.00 24.29  ? 190 PRO C C   1 
ATOM   8373  O  O   . PRO C 1 190 ? 6.005   30.766  -26.129 1.00 29.20  ? 190 PRO C O   1 
ATOM   8374  C  CB  . PRO C 1 190 ? 3.838   32.695  -27.482 1.00 26.46  ? 190 PRO C CB  1 
ATOM   8375  C  CG  . PRO C 1 190 ? 4.914   33.678  -27.169 1.00 27.46  ? 190 PRO C CG  1 
ATOM   8376  C  CD  . PRO C 1 190 ? 4.829   33.888  -25.659 1.00 29.36  ? 190 PRO C CD  1 
ATOM   8377  N  N   . SER C 1 191 ? 4.333   29.469  -26.871 1.00 24.33  ? 191 SER C N   1 
ATOM   8378  C  CA  . SER C 1 191 ? 5.237   28.346  -27.027 1.00 27.63  ? 191 SER C CA  1 
ATOM   8379  C  C   . SER C 1 191 ? 6.148   28.566  -28.234 1.00 29.56  ? 191 SER C C   1 
ATOM   8380  O  O   . SER C 1 191 ? 5.821   29.320  -29.154 1.00 28.09  ? 191 SER C O   1 
ATOM   8381  C  CB  . SER C 1 191 ? 4.446   27.064  -27.195 1.00 27.47  ? 191 SER C CB  1 
ATOM   8382  O  OG  . SER C 1 191 ? 3.696   27.153  -28.379 1.00 25.33  ? 191 SER C OG  1 
ATOM   8383  N  N   . ASP C 1 192 ? 7.313   27.897  -28.221 1.00 25.93  ? 192 ASP C N   1 
ATOM   8384  C  CA  . ASP C 1 192 ? 8.174   27.888  -29.406 1.00 33.95  ? 192 ASP C CA  1 
ATOM   8385  C  C   . ASP C 1 192 ? 7.431   27.352  -30.619 1.00 28.31  ? 192 ASP C C   1 
ATOM   8386  O  O   . ASP C 1 192 ? 7.734   27.723  -31.754 1.00 29.61  ? 192 ASP C O   1 
ATOM   8387  C  CB  . ASP C 1 192 ? 9.427   27.037  -29.182 1.00 32.72  ? 192 ASP C CB  1 
ATOM   8388  C  CG  . ASP C 1 192 ? 10.373  27.614  -28.144 1.00 33.29  ? 192 ASP C CG  1 
ATOM   8389  O  OD1 . ASP C 1 192 ? 10.153  28.740  -27.622 1.00 36.08  ? 192 ASP C OD1 1 
ATOM   8390  O  OD2 . ASP C 1 192 ? 11.379  26.930  -27.867 1.00 34.59  ? 192 ASP C OD2 1 
ATOM   8391  N  N   . GLU C 1 193 ? 6.470   26.463  -30.394 1.00 30.63  ? 193 GLU C N   1 
ATOM   8392  C  CA  . GLU C 1 193 ? 5.666   25.928  -31.483 1.00 34.95  ? 193 GLU C CA  1 
ATOM   8393  C  C   . GLU C 1 193 ? 4.818   27.018  -32.119 1.00 34.57  ? 193 GLU C C   1 
ATOM   8394  O  O   . GLU C 1 193 ? 4.757   27.139  -33.351 1.00 29.68  ? 193 GLU C O   1 
ATOM   8395  C  CB  . GLU C 1 193 ? 4.791   24.802  -30.939 1.00 37.70  ? 193 GLU C CB  1 
ATOM   8396  C  CG  . GLU C 1 193 ? 3.819   24.167  -31.900 1.00 39.88  ? 193 GLU C CG  1 
ATOM   8397  C  CD  . GLU C 1 193 ? 2.826   23.285  -31.159 1.00 51.00  ? 193 GLU C CD  1 
ATOM   8398  O  OE1 . GLU C 1 193 ? 1.988   23.835  -30.400 1.00 53.29  ? 193 GLU C OE1 1 
ATOM   8399  O  OE2 . GLU C 1 193 ? 2.904   22.047  -31.309 1.00 53.45  ? 193 GLU C OE2 1 
ATOM   8400  N  N   . TRP C 1 194 ? 4.137   27.809  -31.288 1.00 28.94  ? 194 TRP C N   1 
ATOM   8401  C  CA  . TRP C 1 194 ? 3.326   28.901  -31.806 1.00 30.92  ? 194 TRP C CA  1 
ATOM   8402  C  C   . TRP C 1 194 ? 4.193   29.925  -32.527 1.00 29.51  ? 194 TRP C C   1 
ATOM   8403  O  O   . TRP C 1 194 ? 3.870   30.354  -33.647 1.00 30.24  ? 194 TRP C O   1 
ATOM   8404  C  CB  . TRP C 1 194 ? 2.548   29.575  -30.674 1.00 31.14  ? 194 TRP C CB  1 
ATOM   8405  C  CG  . TRP C 1 194 ? 1.596   30.580  -31.202 1.00 27.38  ? 194 TRP C CG  1 
ATOM   8406  C  CD1 . TRP C 1 194 ? 0.344   30.351  -31.660 1.00 25.26  ? 194 TRP C CD1 1 
ATOM   8407  C  CD2 . TRP C 1 194 ? 1.844   31.988  -31.376 1.00 29.44  ? 194 TRP C CD2 1 
ATOM   8408  N  NE1 . TRP C 1 194 ? -0.223  31.531  -32.092 1.00 29.66  ? 194 TRP C NE1 1 
ATOM   8409  C  CE2 . TRP C 1 194 ? 0.685   32.547  -31.938 1.00 24.54  ? 194 TRP C CE2 1 
ATOM   8410  C  CE3 . TRP C 1 194 ? 2.937   32.825  -31.102 1.00 27.29  ? 194 TRP C CE3 1 
ATOM   8411  C  CZ2 . TRP C 1 194 ? 0.573   33.916  -32.218 1.00 28.88  ? 194 TRP C CZ2 1 
ATOM   8412  C  CZ3 . TRP C 1 194 ? 2.833   34.174  -31.388 1.00 24.49  ? 194 TRP C CZ3 1 
ATOM   8413  C  CH2 . TRP C 1 194 ? 1.659   34.709  -31.940 1.00 25.26  ? 194 TRP C CH2 1 
ATOM   8414  N  N   . VAL C 1 195 ? 5.307   30.315  -31.898 1.00 24.24  ? 195 VAL C N   1 
ATOM   8415  C  CA  . VAL C 1 195 ? 6.194   31.326  -32.475 1.00 27.67  ? 195 VAL C CA  1 
ATOM   8416  C  C   . VAL C 1 195 ? 6.744   30.848  -33.811 1.00 31.21  ? 195 VAL C C   1 
ATOM   8417  O  O   . VAL C 1 195 ? 6.809   31.618  -34.780 1.00 37.72  ? 195 VAL C O   1 
ATOM   8418  C  CB  . VAL C 1 195 ? 7.331   31.688  -31.499 1.00 22.80  ? 195 VAL C CB  1 
ATOM   8419  C  CG1 . VAL C 1 195 ? 8.340   32.610  -32.180 1.00 29.12  ? 195 VAL C CG1 1 
ATOM   8420  C  CG2 . VAL C 1 195 ? 6.789   32.385  -30.263 1.00 22.41  ? 195 VAL C CG2 1 
ATOM   8421  N  N   . GLU C 1 196 ? 7.159   29.578  -33.881 1.00 27.53  ? 196 GLU C N   1 
ATOM   8422  C  CA  . GLU C 1 196 ? 7.572   28.986  -35.152 1.00 30.91  ? 196 GLU C CA  1 
ATOM   8423  C  C   . GLU C 1 196 ? 6.440   29.041  -36.175 1.00 30.79  ? 196 GLU C C   1 
ATOM   8424  O  O   . GLU C 1 196 ? 6.645   29.454  -37.323 1.00 30.05  ? 196 GLU C O   1 
ATOM   8425  C  CB  . GLU C 1 196 ? 8.040   27.541  -34.931 1.00 34.95  ? 196 GLU C CB  1 
ATOM   8426  C  CG  . GLU C 1 196 ? 8.922   26.950  -36.062 1.00 42.90  ? 196 GLU C CG  1 
ATOM   8427  C  CD  . GLU C 1 196 ? 9.601   25.628  -35.682 1.00 52.91  ? 196 GLU C CD  1 
ATOM   8428  O  OE1 . GLU C 1 196 ? 8.902   24.594  -35.587 1.00 49.90  ? 196 GLU C OE1 1 
ATOM   8429  O  OE2 . GLU C 1 196 ? 10.839  25.628  -35.468 1.00 58.20  ? 196 GLU C OE2 1 
ATOM   8430  N  N   . GLN C 1 197 ? 5.232   28.620  -35.778 1.00 29.40  ? 197 GLN C N   1 
ATOM   8431  C  CA  . GLN C 1 197 ? 4.093   28.665  -36.697 1.00 28.11  ? 197 GLN C CA  1 
ATOM   8432  C  C   . GLN C 1 197 ? 3.700   30.095  -37.063 1.00 31.17  ? 197 GLN C C   1 
ATOM   8433  O  O   . GLN C 1 197 ? 3.232   30.334  -38.179 1.00 31.33  ? 197 GLN C O   1 
ATOM   8434  C  CB  . GLN C 1 197 ? 2.894   27.914  -36.102 1.00 34.09  ? 197 GLN C CB  1 
ATOM   8435  C  CG  . GLN C 1 197 ? 1.576   28.009  -36.907 1.00 37.69  ? 197 GLN C CG  1 
ATOM   8436  C  CD  . GLN C 1 197 ? 1.639   27.376  -38.312 1.00 44.47  ? 197 GLN C CD  1 
ATOM   8437  O  OE1 . GLN C 1 197 ? 2.717   27.093  -38.852 1.00 42.41  ? 197 GLN C OE1 1 
ATOM   8438  N  NE2 . GLN C 1 197 ? 0.467   27.177  -38.913 1.00 45.94  ? 197 GLN C NE2 1 
ATOM   8439  N  N   . TRP C 1 198 ? 3.853   31.049  -36.140 1.00 28.52  ? 198 TRP C N   1 
ATOM   8440  C  CA  . TRP C 1 198 ? 3.644   32.455  -36.470 1.00 30.07  ? 198 TRP C CA  1 
ATOM   8441  C  C   . TRP C 1 198 ? 4.536   32.878  -37.635 1.00 28.48  ? 198 TRP C C   1 
ATOM   8442  O  O   . TRP C 1 198 ? 4.061   33.437  -38.626 1.00 28.61  ? 198 TRP C O   1 
ATOM   8443  C  CB  . TRP C 1 198 ? 3.888   33.309  -35.212 1.00 27.32  ? 198 TRP C CB  1 
ATOM   8444  C  CG  . TRP C 1 198 ? 4.114   34.801  -35.393 1.00 31.81  ? 198 TRP C CG  1 
ATOM   8445  C  CD1 . TRP C 1 198 ? 5.314   35.455  -35.372 1.00 26.52  ? 198 TRP C CD1 1 
ATOM   8446  C  CD2 . TRP C 1 198 ? 3.110   35.818  -35.538 1.00 26.47  ? 198 TRP C CD2 1 
ATOM   8447  N  NE1 . TRP C 1 198 ? 5.123   36.801  -35.529 1.00 25.86  ? 198 TRP C NE1 1 
ATOM   8448  C  CE2 . TRP C 1 198 ? 3.779   37.050  -35.639 1.00 25.89  ? 198 TRP C CE2 1 
ATOM   8449  C  CE3 . TRP C 1 198 ? 1.712   35.798  -35.623 1.00 21.78  ? 198 TRP C CE3 1 
ATOM   8450  C  CZ2 . TRP C 1 198 ? 3.096   38.261  -35.805 1.00 28.43  ? 198 TRP C CZ2 1 
ATOM   8451  C  CZ3 . TRP C 1 198 ? 1.042   36.990  -35.793 1.00 25.53  ? 198 TRP C CZ3 1 
ATOM   8452  C  CH2 . TRP C 1 198 ? 1.731   38.210  -35.885 1.00 23.91  ? 198 TRP C CH2 1 
ATOM   8453  N  N   . PHE C 1 199 ? 5.826   32.585  -37.553 1.00 29.94  ? 199 PHE C N   1 
ATOM   8454  C  CA  . PHE C 1 199 ? 6.720   33.034  -38.611 1.00 29.21  ? 199 PHE C CA  1 
ATOM   8455  C  C   . PHE C 1 199 ? 6.487   32.274  -39.907 1.00 31.08  ? 199 PHE C C   1 
ATOM   8456  O  O   . PHE C 1 199 ? 6.681   32.833  -40.987 1.00 33.52  ? 199 PHE C O   1 
ATOM   8457  C  CB  . PHE C 1 199 ? 8.173   32.915  -38.152 1.00 30.08  ? 199 PHE C CB  1 
ATOM   8458  C  CG  . PHE C 1 199 ? 8.578   34.004  -37.233 1.00 28.70  ? 199 PHE C CG  1 
ATOM   8459  C  CD1 . PHE C 1 199 ? 8.751   35.297  -37.715 1.00 31.48  ? 199 PHE C CD1 1 
ATOM   8460  C  CD2 . PHE C 1 199 ? 8.760   33.768  -35.885 1.00 25.35  ? 199 PHE C CD2 1 
ATOM   8461  C  CE1 . PHE C 1 199 ? 9.106   36.332  -36.867 1.00 23.48  ? 199 PHE C CE1 1 
ATOM   8462  C  CE2 . PHE C 1 199 ? 9.108   34.806  -35.023 1.00 27.93  ? 199 PHE C CE2 1 
ATOM   8463  C  CZ  . PHE C 1 199 ? 9.293   36.085  -35.518 1.00 28.02  ? 199 PHE C CZ  1 
ATOM   8464  N  N   . ALA C 1 200 ? 6.043   31.019  -39.829 1.00 28.10  ? 200 ALA C N   1 
ATOM   8465  C  CA  . ALA C 1 200 ? 5.722   30.296  -41.048 1.00 28.44  ? 200 ALA C CA  1 
ATOM   8466  C  C   . ALA C 1 200 ? 4.485   30.882  -41.722 1.00 32.69  ? 200 ALA C C   1 
ATOM   8467  O  O   . ALA C 1 200 ? 4.428   30.990  -42.960 1.00 23.85  ? 200 ALA C O   1 
ATOM   8468  C  CB  . ALA C 1 200 ? 5.528   28.809  -40.745 1.00 32.44  ? 200 ALA C CB  1 
ATOM   8469  N  N   . LEU C 1 201 ? 3.477   31.250  -40.926 1.00 26.22  ? 201 LEU C N   1 
ATOM   8470  C  CA  . LEU C 1 201 ? 2.269   31.837  -41.493 1.00 30.67  ? 201 LEU C CA  1 
ATOM   8471  C  C   . LEU C 1 201 ? 2.585   33.155  -42.205 1.00 29.38  ? 201 LEU C C   1 
ATOM   8472  O  O   . LEU C 1 201 ? 2.142   33.384  -43.340 1.00 30.27  ? 201 LEU C O   1 
ATOM   8473  C  CB  . LEU C 1 201 ? 1.219   32.046  -40.401 1.00 31.38  ? 201 LEU C CB  1 
ATOM   8474  C  CG  . LEU C 1 201 ? 0.470   30.821  -39.850 1.00 32.97  ? 201 LEU C CG  1 
ATOM   8475  C  CD1 . LEU C 1 201 ? -0.424  31.211  -38.663 1.00 27.64  ? 201 LEU C CD1 1 
ATOM   8476  C  CD2 . LEU C 1 201 ? -0.344  30.123  -40.924 1.00 30.43  ? 201 LEU C CD2 1 
ATOM   8477  N  N   . LEU C 1 202 ? 3.364   34.025  -41.553 1.00 26.19  ? 202 LEU C N   1 
ATOM   8478  C  CA  . LEU C 1 202 ? 3.728   35.304  -42.153 1.00 31.07  ? 202 LEU C CA  1 
ATOM   8479  C  C   . LEU C 1 202 ? 4.364   35.114  -43.528 1.00 28.72  ? 202 LEU C C   1 
ATOM   8480  O  O   . LEU C 1 202 ? 3.907   35.693  -44.524 1.00 28.33  ? 202 LEU C O   1 
ATOM   8481  C  CB  . LEU C 1 202 ? 4.673   36.063  -41.227 1.00 31.26  ? 202 LEU C CB  1 
ATOM   8482  C  CG  . LEU C 1 202 ? 4.087   36.484  -39.878 1.00 28.71  ? 202 LEU C CG  1 
ATOM   8483  C  CD1 . LEU C 1 202 ? 5.221   36.965  -38.997 1.00 22.63  ? 202 LEU C CD1 1 
ATOM   8484  C  CD2 . LEU C 1 202 ? 3.035   37.584  -40.053 1.00 27.82  ? 202 LEU C CD2 1 
ATOM   8485  N  N   . SER C 1 203 ? 5.412   34.285  -43.600 1.00 29.36  ? 203 SER C N   1 
ATOM   8486  C  CA  . SER C 1 203 ? 6.049   33.986  -44.883 1.00 34.84  ? 203 SER C CA  1 
ATOM   8487  C  C   . SER C 1 203 ? 5.052   33.400  -45.877 1.00 32.27  ? 203 SER C C   1 
ATOM   8488  O  O   . SER C 1 203 ? 5.039   33.784  -47.050 1.00 33.76  ? 203 SER C O   1 
ATOM   8489  C  CB  . SER C 1 203 ? 7.231   33.027  -44.682 1.00 32.83  ? 203 SER C CB  1 
ATOM   8490  O  OG  . SER C 1 203 ? 7.560   32.368  -45.901 1.00 34.41  ? 203 SER C OG  1 
ATOM   8491  N  N   . THR C 1 204 ? 4.209   32.471  -45.427 1.00 26.57  ? 204 THR C N   1 
ATOM   8492  C  CA  . THR C 1 204 ? 3.205   31.887  -46.306 1.00 27.56  ? 204 THR C CA  1 
ATOM   8493  C  C   . THR C 1 204 ? 2.293   32.957  -46.901 1.00 33.55  ? 204 THR C C   1 
ATOM   8494  O  O   . THR C 1 204 ? 1.990   32.923  -48.099 1.00 28.92  ? 204 THR C O   1 
ATOM   8495  C  CB  . THR C 1 204 ? 2.372   30.853  -45.544 1.00 27.69  ? 204 THR C CB  1 
ATOM   8496  O  OG1 . THR C 1 204 ? 3.100   29.624  -45.450 1.00 31.19  ? 204 THR C OG1 1 
ATOM   8497  C  CG2 . THR C 1 204 ? 1.066   30.584  -46.254 1.00 22.88  ? 204 THR C CG2 1 
ATOM   8498  N  N   . TYR C 1 205 ? 1.830   33.906  -46.084 1.00 27.53  ? 205 TYR C N   1 
ATOM   8499  C  CA  . TYR C 1 205 ? 0.830   34.852  -46.548 1.00 23.28  ? 205 TYR C CA  1 
ATOM   8500  C  C   . TYR C 1 205 ? 1.426   36.190  -46.940 1.00 25.54  ? 205 TYR C C   1 
ATOM   8501  O  O   . TYR C 1 205 ? 0.676   37.091  -47.314 1.00 27.37  ? 205 TYR C O   1 
ATOM   8502  C  CB  . TYR C 1 205 ? -0.269  35.045  -45.503 1.00 27.25  ? 205 TYR C CB  1 
ATOM   8503  C  CG  . TYR C 1 205 ? -1.153  33.839  -45.410 1.00 27.62  ? 205 TYR C CG  1 
ATOM   8504  C  CD1 . TYR C 1 205 ? -2.170  33.644  -46.322 1.00 28.72  ? 205 TYR C CD1 1 
ATOM   8505  C  CD2 . TYR C 1 205 ? -0.936  32.864  -44.438 1.00 29.64  ? 205 TYR C CD2 1 
ATOM   8506  C  CE1 . TYR C 1 205 ? -2.960  32.528  -46.271 1.00 30.17  ? 205 TYR C CE1 1 
ATOM   8507  C  CE2 . TYR C 1 205 ? -1.735  31.733  -44.373 1.00 29.81  ? 205 TYR C CE2 1 
ATOM   8508  C  CZ  . TYR C 1 205 ? -2.744  31.579  -45.290 1.00 27.06  ? 205 TYR C CZ  1 
ATOM   8509  O  OH  . TYR C 1 205 ? -3.540  30.479  -45.271 1.00 27.95  ? 205 TYR C OH  1 
ATOM   8510  N  N   . GLY C 1 206 ? 2.743   36.333  -46.879 1.00 23.95  ? 206 GLY C N   1 
ATOM   8511  C  CA  . GLY C 1 206 ? 3.387   37.535  -47.371 1.00 28.41  ? 206 GLY C CA  1 
ATOM   8512  C  C   . GLY C 1 206 ? 3.152   38.743  -46.500 1.00 27.53  ? 206 GLY C C   1 
ATOM   8513  O  O   . GLY C 1 206 ? 3.035   39.859  -47.018 1.00 27.79  ? 206 GLY C O   1 
ATOM   8514  N  N   . LEU C 1 207 ? 3.090   38.553  -45.186 1.00 26.47  ? 207 LEU C N   1 
ATOM   8515  C  CA  . LEU C 1 207 ? 2.749   39.613  -44.255 1.00 22.97  ? 207 LEU C CA  1 
ATOM   8516  C  C   . LEU C 1 207 ? 3.941   40.004  -43.387 1.00 24.54  ? 207 LEU C C   1 
ATOM   8517  O  O   . LEU C 1 207 ? 4.798   39.182  -43.061 1.00 29.63  ? 207 LEU C O   1 
ATOM   8518  C  CB  . LEU C 1 207 ? 1.562   39.176  -43.366 1.00 24.22  ? 207 LEU C CB  1 
ATOM   8519  C  CG  . LEU C 1 207 ? 0.264   38.880  -44.126 1.00 26.24  ? 207 LEU C CG  1 
ATOM   8520  C  CD1 . LEU C 1 207 ? -0.838  38.325  -43.212 1.00 28.63  ? 207 LEU C CD1 1 
ATOM   8521  C  CD2 . LEU C 1 207 ? -0.212  40.141  -44.854 1.00 21.62  ? 207 LEU C CD2 1 
ATOM   8522  N  N   . GLU C 1 208 ? 3.965   41.264  -42.972 1.00 26.59  ? 208 GLU C N   1 
ATOM   8523  C  CA  . GLU C 1 208 ? 4.994   41.714  -42.050 1.00 34.26  ? 208 GLU C CA  1 
ATOM   8524  C  C   . GLU C 1 208 ? 4.350   42.270  -40.789 1.00 29.96  ? 208 GLU C C   1 
ATOM   8525  O  O   . GLU C 1 208 ? 3.296   42.914  -40.856 1.00 29.13  ? 208 GLU C O   1 
ATOM   8526  C  CB  . GLU C 1 208 ? 5.904   42.785  -42.676 1.00 33.49  ? 208 GLU C CB  1 
ATOM   8527  C  CG  . GLU C 1 208 ? 5.546   44.208  -42.277 1.00 41.21  ? 208 GLU C CG  1 
ATOM   8528  C  CD  . GLU C 1 208 ? 6.598   45.238  -42.675 1.00 46.21  ? 208 GLU C CD  1 
ATOM   8529  O  OE1 . GLU C 1 208 ? 7.694   45.256  -42.062 1.00 48.17  ? 208 GLU C OE1 1 
ATOM   8530  O  OE2 . GLU C 1 208 ? 6.304   46.053  -43.576 1.00 47.54  ? 208 GLU C OE2 1 
ATOM   8531  N  N   . PRO C 1 209 ? 4.912   41.972  -39.624 1.00 32.74  ? 209 PRO C N   1 
ATOM   8532  C  CA  . PRO C 1 209 ? 4.344   42.504  -38.376 1.00 29.76  ? 209 PRO C CA  1 
ATOM   8533  C  C   . PRO C 1 209 ? 4.636   43.994  -38.233 1.00 32.55  ? 209 PRO C C   1 
ATOM   8534  O  O   . PRO C 1 209 ? 5.763   44.441  -38.451 1.00 33.57  ? 209 PRO C O   1 
ATOM   8535  C  CB  . PRO C 1 209 ? 5.037   41.670  -37.281 1.00 29.96  ? 209 PRO C CB  1 
ATOM   8536  C  CG  . PRO C 1 209 ? 6.167   40.928  -37.965 1.00 32.15  ? 209 PRO C CG  1 
ATOM   8537  C  CD  . PRO C 1 209 ? 5.784   40.804  -39.406 1.00 29.75  ? 209 PRO C CD  1 
ATOM   8538  N  N   . THR C 1 210 ? 3.607   44.768  -37.858 1.00 29.86  ? 210 THR C N   1 
ATOM   8539  C  CA  . THR C 1 210 ? 3.735   46.217  -37.827 1.00 28.69  ? 210 THR C CA  1 
ATOM   8540  C  C   . THR C 1 210 ? 3.627   46.671  -36.383 1.00 28.54  ? 210 THR C C   1 
ATOM   8541  O  O   . THR C 1 210 ? 4.653   46.769  -35.696 1.00 31.24  ? 210 THR C O   1 
ATOM   8542  C  CB  . THR C 1 210 ? 2.739   46.896  -38.781 1.00 26.79  ? 210 THR C CB  1 
ATOM   8543  O  OG1 . THR C 1 210 ? 1.396   46.608  -38.398 1.00 30.20  ? 210 THR C OG1 1 
ATOM   8544  C  CG2 . THR C 1 210 ? 2.963   46.396  -40.209 1.00 27.34  ? 210 THR C CG2 1 
ATOM   8545  N  N   . ASN C 1 211 ? 2.438   46.963  -35.873 1.00 28.23  ? 211 ASN C N   1 
ATOM   8546  C  CA  . ASN C 1 211 ? 2.271   47.434  -34.504 1.00 25.61  ? 211 ASN C CA  1 
ATOM   8547  C  C   . ASN C 1 211 ? 1.717   46.322  -33.605 1.00 28.28  ? 211 ASN C C   1 
ATOM   8548  O  O   . ASN C 1 211 ? 0.839   45.562  -34.015 1.00 24.72  ? 211 ASN C O   1 
ATOM   8549  C  CB  . ASN C 1 211 ? 1.330   48.635  -34.473 1.00 25.61  ? 211 ASN C CB  1 
ATOM   8550  C  CG  . ASN C 1 211 ? 1.132   49.174  -33.086 1.00 29.18  ? 211 ASN C CG  1 
ATOM   8551  O  OD1 . ASN C 1 211 ? 2.102   49.416  -32.374 1.00 32.27  ? 211 ASN C OD1 1 
ATOM   8552  N  ND2 . ASN C 1 211 ? -0.127  49.369  -32.685 1.00 31.36  ? 211 ASN C ND2 1 
ATOM   8553  N  N   . MET C 1 212 ? 2.231   46.229  -32.376 1.00 25.10  ? 212 MET C N   1 
ATOM   8554  C  CA  . MET C 1 212 ? 1.685   45.328  -31.360 1.00 29.94  ? 212 MET C CA  1 
ATOM   8555  C  C   . MET C 1 212 ? 1.109   46.187  -30.241 1.00 32.65  ? 212 MET C C   1 
ATOM   8556  O  O   . MET C 1 212 ? 1.858   46.877  -29.544 1.00 29.64  ? 212 MET C O   1 
ATOM   8557  C  CB  . MET C 1 212 ? 2.746   44.377  -30.798 1.00 26.21  ? 212 MET C CB  1 
ATOM   8558  C  CG  . MET C 1 212 ? 2.149   43.322  -29.822 1.00 29.13  ? 212 MET C CG  1 
ATOM   8559  S  SD  . MET C 1 212 ? 3.323   42.308  -28.884 1.00 31.64  ? 212 MET C SD  1 
ATOM   8560  C  CE  . MET C 1 212 ? 3.471   43.242  -27.366 1.00 24.33  ? 212 MET C CE  1 
ATOM   8561  N  N   . GLY C 1 213 ? -0.213  46.146  -30.063 1.00 29.93  ? 213 GLY C N   1 
ATOM   8562  C  CA  . GLY C 1 213 ? -0.826  46.864  -28.956 1.00 29.81  ? 213 GLY C CA  1 
ATOM   8563  C  C   . GLY C 1 213 ? -0.546  46.207  -27.616 1.00 28.51  ? 213 GLY C C   1 
ATOM   8564  O  O   . GLY C 1 213 ? -0.403  44.987  -27.507 1.00 29.79  ? 213 GLY C O   1 
ATOM   8565  N  N   . SER C 1 214 ? -0.452  47.039  -26.579 1.00 32.69  ? 214 SER C N   1 
ATOM   8566  C  CA  . SER C 1 214 ? -0.097  46.596  -25.235 1.00 28.48  ? 214 SER C CA  1 
ATOM   8567  C  C   . SER C 1 214 ? -0.665  47.607  -24.252 1.00 30.90  ? 214 SER C C   1 
ATOM   8568  O  O   . SER C 1 214 ? -1.183  48.657  -24.645 1.00 31.72  ? 214 SER C O   1 
ATOM   8569  C  CB  . SER C 1 214 ? 1.425   46.446  -25.073 1.00 34.51  ? 214 SER C CB  1 
ATOM   8570  O  OG  . SER C 1 214 ? 2.071   47.712  -24.967 1.00 27.23  ? 214 SER C OG  1 
ATOM   8571  N  N   . TRP C 1 215 ? -0.562  47.289  -22.962 1.00 32.17  ? 215 TRP C N   1 
ATOM   8572  C  CA  . TRP C 1 215 ? -1.227  48.061  -21.928 1.00 33.94  ? 215 TRP C CA  1 
ATOM   8573  C  C   . TRP C 1 215 ? -0.301  48.360  -20.760 1.00 30.14  ? 215 TRP C C   1 
ATOM   8574  O  O   . TRP C 1 215 ? 0.606   47.586  -20.434 1.00 28.30  ? 215 TRP C O   1 
ATOM   8575  C  CB  . TRP C 1 215 ? -2.486  47.330  -21.404 1.00 30.17  ? 215 TRP C CB  1 
ATOM   8576  C  CG  . TRP C 1 215 ? -3.597  47.472  -22.360 1.00 28.13  ? 215 TRP C CG  1 
ATOM   8577  C  CD1 . TRP C 1 215 ? -4.565  48.418  -22.343 1.00 29.59  ? 215 TRP C CD1 1 
ATOM   8578  C  CD2 . TRP C 1 215 ? -3.838  46.664  -23.514 1.00 25.68  ? 215 TRP C CD2 1 
ATOM   8579  N  NE1 . TRP C 1 215 ? -5.410  48.248  -23.421 1.00 28.99  ? 215 TRP C NE1 1 
ATOM   8580  C  CE2 . TRP C 1 215 ? -4.977  47.173  -24.151 1.00 25.09  ? 215 TRP C CE2 1 
ATOM   8581  C  CE3 . TRP C 1 215 ? -3.218  45.535  -24.051 1.00 31.74  ? 215 TRP C CE3 1 
ATOM   8582  C  CZ2 . TRP C 1 215 ? -5.510  46.595  -25.309 1.00 28.18  ? 215 TRP C CZ2 1 
ATOM   8583  C  CZ3 . TRP C 1 215 ? -3.744  44.963  -25.197 1.00 25.03  ? 215 TRP C CZ3 1 
ATOM   8584  C  CH2 . TRP C 1 215 ? -4.875  45.499  -25.818 1.00 26.49  ? 215 TRP C CH2 1 
ATOM   8585  N  N   . ILE C 1 216 ? -0.556  49.495  -20.127 1.00 30.74  ? 216 ILE C N   1 
ATOM   8586  C  CA  . ILE C 1 216 ? -0.034  49.796  -18.797 1.00 30.45  ? 216 ILE C CA  1 
ATOM   8587  C  C   . ILE C 1 216 ? -1.259  49.946  -17.907 1.00 32.14  ? 216 ILE C C   1 
ATOM   8588  O  O   . ILE C 1 216 ? -1.830  51.034  -17.769 1.00 30.93  ? 216 ILE C O   1 
ATOM   8589  C  CB  . ILE C 1 216 ? 0.848   51.040  -18.772 1.00 33.89  ? 216 ILE C CB  1 
ATOM   8590  C  CG1 . ILE C 1 216 ? 2.030   50.834  -19.717 1.00 33.31  ? 216 ILE C CG1 1 
ATOM   8591  C  CG2 . ILE C 1 216 ? 1.379   51.295  -17.353 1.00 32.57  ? 216 ILE C CG2 1 
ATOM   8592  C  CD1 . ILE C 1 216 ? 3.011   51.959  -19.669 1.00 37.29  ? 216 ILE C CD1 1 
ATOM   8593  N  N   . ASP C 1 217 ? -1.684  48.832  -17.312 1.00 33.51  ? 217 ASP C N   1 
ATOM   8594  C  CA  . ASP C 1 217 ? -2.921  48.777  -16.529 1.00 34.76  ? 217 ASP C CA  1 
ATOM   8595  C  C   . ASP C 1 217 ? -2.639  49.312  -15.129 1.00 35.79  ? 217 ASP C C   1 
ATOM   8596  O  O   . ASP C 1 217 ? -2.382  48.559  -14.183 1.00 31.23  ? 217 ASP C O   1 
ATOM   8597  C  CB  . ASP C 1 217 ? -3.463  47.354  -16.478 1.00 27.40  ? 217 ASP C CB  1 
ATOM   8598  C  CG  . ASP C 1 217 ? -3.866  46.837  -17.834 1.00 34.65  ? 217 ASP C CG  1 
ATOM   8599  O  OD1 . ASP C 1 217 ? -4.708  47.480  -18.491 1.00 42.97  ? 217 ASP C OD1 1 
ATOM   8600  O  OD2 . ASP C 1 217 ? -3.345  45.783  -18.249 1.00 27.35  ? 217 ASP C OD2 1 
ATOM   8601  N  N   . THR C 1 218 ? -2.721  50.648  -15.004 1.00 34.15  ? 218 THR C N   1 
ATOM   8602  C  CA  . THR C 1 218 ? -2.359  51.326  -13.755 1.00 33.33  ? 218 THR C CA  1 
ATOM   8603  C  C   . THR C 1 218 ? -3.263  50.932  -12.590 1.00 28.31  ? 218 THR C C   1 
ATOM   8604  O  O   . THR C 1 218 ? -2.843  51.000  -11.432 1.00 33.21  ? 218 THR C O   1 
ATOM   8605  C  CB  . THR C 1 218 ? -2.431  52.836  -13.935 1.00 35.97  ? 218 THR C CB  1 
ATOM   8606  O  OG1 . THR C 1 218 ? -3.657  53.163  -14.597 1.00 35.20  ? 218 THR C OG1 1 
ATOM   8607  C  CG2 . THR C 1 218 ? -1.244  53.352  -14.768 1.00 30.84  ? 218 THR C CG2 1 
ATOM   8608  N  N   . ARG C 1 219 ? -4.513  50.573  -12.863 1.00 30.47  ? 219 ARG C N   1 
ATOM   8609  C  CA  . ARG C 1 219 ? -5.442  50.127  -11.831 1.00 31.12  ? 219 ARG C CA  1 
ATOM   8610  C  C   . ARG C 1 219 ? -5.372  48.620  -11.581 1.00 28.35  ? 219 ARG C C   1 
ATOM   8611  O  O   . ARG C 1 219 ? -6.373  48.011  -11.173 1.00 27.70  ? 219 ARG C O   1 
ATOM   8612  C  CB  . ARG C 1 219 ? -6.863  50.533  -12.212 1.00 28.43  ? 219 ARG C CB  1 
ATOM   8613  C  CG  . ARG C 1 219 ? -6.981  51.926  -12.796 1.00 31.70  ? 219 ARG C CG  1 
ATOM   8614  C  CD  . ARG C 1 219 ? -8.438  52.387  -12.776 1.00 29.85  ? 219 ARG C CD  1 
ATOM   8615  N  NE  . ARG C 1 219 ? -8.557  53.743  -13.292 1.00 36.44  ? 219 ARG C NE  1 
ATOM   8616  C  CZ  . ARG C 1 219 ? -9.358  54.134  -14.276 1.00 35.96  ? 219 ARG C CZ  1 
ATOM   8617  N  NH1 . ARG C 1 219 ? -10.207 53.299  -14.864 1.00 29.00  ? 219 ARG C NH1 1 
ATOM   8618  N  NH2 . ARG C 1 219 ? -9.302  55.400  -14.685 1.00 35.60  ? 219 ARG C NH2 1 
ATOM   8619  N  N   . LEU C 1 220 ? -4.216  48.003  -11.826 1.00 28.54  ? 220 LEU C N   1 
ATOM   8620  C  CA  . LEU C 1 220 ? -4.070  46.557  -11.672 1.00 31.88  ? 220 LEU C CA  1 
ATOM   8621  C  C   . LEU C 1 220 ? -4.573  46.069  -10.322 1.00 27.89  ? 220 LEU C C   1 
ATOM   8622  O  O   . LEU C 1 220 ? -5.118  44.967  -10.218 1.00 29.44  ? 220 LEU C O   1 
ATOM   8623  C  CB  . LEU C 1 220 ? -2.601  46.170  -11.848 1.00 29.34  ? 220 LEU C CB  1 
ATOM   8624  C  CG  . LEU C 1 220 ? -2.367  44.679  -12.062 1.00 31.00  ? 220 LEU C CG  1 
ATOM   8625  C  CD1 . LEU C 1 220 ? -2.933  44.262  -13.403 1.00 34.27  ? 220 LEU C CD1 1 
ATOM   8626  C  CD2 . LEU C 1 220 ? -0.892  44.346  -11.954 1.00 24.95  ? 220 LEU C CD2 1 
ATOM   8627  N  N   . HIS C 1 221 ? -4.409  46.874  -9.284  1.00 29.27  ? 221 HIS C N   1 
ATOM   8628  C  CA  . HIS C 1 221 ? -4.771  46.486  -7.929  1.00 33.42  ? 221 HIS C CA  1 
ATOM   8629  C  C   . HIS C 1 221 ? -5.514  47.628  -7.265  1.00 35.97  ? 221 HIS C C   1 
ATOM   8630  O  O   . HIS C 1 221 ? -5.170  48.070  -6.171  1.00 35.99  ? 221 HIS C O   1 
ATOM   8631  C  CB  . HIS C 1 221 ? -3.535  46.113  -7.116  1.00 35.74  ? 221 HIS C CB  1 
ATOM   8632  C  CG  . HIS C 1 221 ? -2.831  44.891  -7.609  1.00 35.92  ? 221 HIS C CG  1 
ATOM   8633  N  ND1 . HIS C 1 221 ? -3.370  43.624  -7.497  1.00 38.37  ? 221 HIS C ND1 1 
ATOM   8634  C  CD2 . HIS C 1 221 ? -1.637  44.740  -8.228  1.00 34.39  ? 221 HIS C CD2 1 
ATOM   8635  C  CE1 . HIS C 1 221 ? -2.534  42.748  -8.023  1.00 37.71  ? 221 HIS C CE1 1 
ATOM   8636  N  NE2 . HIS C 1 221 ? -1.478  43.400  -8.478  1.00 35.94  ? 221 HIS C NE2 1 
ATOM   8637  N  N   . SER C 1 222 ? -6.525  48.152  -7.949  1.00 34.69  ? 222 SER C N   1 
ATOM   8638  C  CA  . SER C 1 222 ? -7.251  49.292  -7.413  1.00 37.46  ? 222 SER C CA  1 
ATOM   8639  C  C   . SER C 1 222 ? -8.382  48.860  -6.488  1.00 43.82  ? 222 SER C C   1 
ATOM   8640  O  O   . SER C 1 222 ? -8.807  49.656  -5.642  1.00 42.72  ? 222 SER C O   1 
ATOM   8641  C  CB  . SER C 1 222 ? -7.771  50.174  -8.564  1.00 32.95  ? 222 SER C CB  1 
ATOM   8642  O  OG  . SER C 1 222 ? -8.897  49.617  -9.219  1.00 35.39  ? 222 SER C OG  1 
ATOM   8643  N  N   . SER C 1 223 ? -8.819  47.604  -6.594  1.00 30.26  ? 223 SER C N   1 
ATOM   8644  C  CA  . SER C 1 223 ? -9.959  47.048  -5.887  1.00 36.88  ? 223 SER C CA  1 
ATOM   8645  C  C   . SER C 1 223 ? -9.527  46.301  -4.621  1.00 31.83  ? 223 SER C C   1 
ATOM   8646  O  O   . SER C 1 223 ? -8.376  45.874  -4.482  1.00 31.88  ? 223 SER C O   1 
ATOM   8647  C  CB  . SER C 1 223 ? -10.719 46.093  -6.807  1.00 33.65  ? 223 SER C CB  1 
ATOM   8648  O  OG  . SER C 1 223 ? -11.511 46.788  -7.729  1.00 35.81  ? 223 SER C OG  1 
ATOM   8649  N  N   . GLY C 1 224 ? -10.479 46.140  -3.696  1.00 35.61  ? 224 GLY C N   1 
ATOM   8650  C  CA  . GLY C 1 224 ? -10.244 45.402  -2.465  1.00 35.33  ? 224 GLY C CA  1 
ATOM   8651  C  C   . GLY C 1 224 ? -9.567  46.206  -1.369  1.00 42.59  ? 224 GLY C C   1 
ATOM   8652  O  O   . GLY C 1 224 ? -9.091  47.323  -1.588  1.00 46.35  ? 224 GLY C O   1 
ATOM   8653  N  N   . PRO C 1 225 ? -9.495  45.638  -0.160  1.00 43.38  ? 225 PRO C N   1 
ATOM   8654  C  CA  . PRO C 1 225 ? -8.946  46.403  0.973   1.00 43.00  ? 225 PRO C CA  1 
ATOM   8655  C  C   . PRO C 1 225 ? -7.471  46.720  0.833   1.00 48.19  ? 225 PRO C C   1 
ATOM   8656  O  O   . PRO C 1 225 ? -7.002  47.697  1.429   1.00 47.78  ? 225 PRO C O   1 
ATOM   8657  C  CB  . PRO C 1 225 ? -9.205  45.480  2.175   1.00 45.91  ? 225 PRO C CB  1 
ATOM   8658  C  CG  . PRO C 1 225 ? -10.266 44.520  1.702   1.00 51.37  ? 225 PRO C CG  1 
ATOM   8659  C  CD  . PRO C 1 225 ? -9.947  44.303  0.255   1.00 43.87  ? 225 PRO C CD  1 
ATOM   8660  N  N   . ASN C 1 226 ? -6.722  45.922  0.075   1.00 46.46  ? 226 ASN C N   1 
ATOM   8661  C  CA  . ASN C 1 226 ? -5.293  46.142  -0.136  1.00 48.32  ? 226 ASN C CA  1 
ATOM   8662  C  C   . ASN C 1 226 ? -5.008  46.871  -1.441  1.00 49.73  ? 226 ASN C C   1 
ATOM   8663  O  O   . ASN C 1 226 ? -4.045  46.552  -2.148  1.00 50.95  ? 226 ASN C O   1 
ATOM   8664  C  CB  . ASN C 1 226 ? -4.547  44.816  -0.093  1.00 48.98  ? 226 ASN C CB  1 
ATOM   8665  C  CG  . ASN C 1 226 ? -4.497  44.235  1.291   1.00 53.41  ? 226 ASN C CG  1 
ATOM   8666  O  OD1 . ASN C 1 226 ? -5.512  44.176  1.992   1.00 54.72  ? 226 ASN C OD1 1 
ATOM   8667  N  ND2 . ASN C 1 226 ? -3.307  43.817  1.709   1.00 55.11  ? 226 ASN C ND2 1 
ATOM   8668  N  N   . GLY C 1 227 ? -5.828  47.862  -1.780  1.00 46.98  ? 227 GLY C N   1 
ATOM   8669  C  CA  . GLY C 1 227 ? -5.604  48.613  -2.997  1.00 44.84  ? 227 GLY C CA  1 
ATOM   8670  C  C   . GLY C 1 227 ? -4.257  49.307  -2.999  1.00 53.16  ? 227 GLY C C   1 
ATOM   8671  O  O   . GLY C 1 227 ? -3.668  49.586  -1.951  1.00 57.87  ? 227 GLY C O   1 
ATOM   8672  N  N   . ARG C 1 228 ? -3.774  49.589  -4.212  1.00 49.43  ? 228 ARG C N   1 
ATOM   8673  C  CA  . ARG C 1 228 ? -2.455  50.166  -4.432  1.00 44.14  ? 228 ARG C CA  1 
ATOM   8674  C  C   . ARG C 1 228 ? -2.331  50.568  -5.891  1.00 48.91  ? 228 ARG C C   1 
ATOM   8675  O  O   . ARG C 1 228 ? -2.933  49.941  -6.768  1.00 48.53  ? 228 ARG C O   1 
ATOM   8676  C  CB  . ARG C 1 228 ? -1.340  49.180  -4.050  1.00 44.75  ? 228 ARG C CB  1 
ATOM   8677  C  CG  . ARG C 1 228 ? -1.257  47.912  -4.891  1.00 40.47  ? 228 ARG C CG  1 
ATOM   8678  C  CD  . ARG C 1 228 ? 0.063   47.223  -4.626  1.00 41.09  ? 228 ARG C CD  1 
ATOM   8679  N  NE  . ARG C 1 228 ? 0.305   46.068  -5.485  1.00 51.07  ? 228 ARG C NE  1 
ATOM   8680  C  CZ  . ARG C 1 228 ? -0.114  44.834  -5.233  1.00 44.00  ? 228 ARG C CZ  1 
ATOM   8681  N  NH1 . ARG C 1 228 ? -0.897  44.564  -4.197  1.00 42.49  ? 228 ARG C NH1 1 
ATOM   8682  N  NH2 . ARG C 1 228 ? 0.262   43.843  -6.039  1.00 42.16  ? 228 ARG C NH2 1 
ATOM   8683  N  N   . ASP C 1 229 ? -1.552  51.617  -6.146  1.00 50.24  ? 229 ASP C N   1 
ATOM   8684  C  CA  . ASP C 1 229 ? -1.328  52.044  -7.517  1.00 47.21  ? 229 ASP C CA  1 
ATOM   8685  C  C   . ASP C 1 229 ? -0.086  51.367  -8.090  1.00 43.94  ? 229 ASP C C   1 
ATOM   8686  O  O   . ASP C 1 229 ? 0.758   50.844  -7.358  1.00 49.74  ? 229 ASP C O   1 
ATOM   8687  C  CB  . ASP C 1 229 ? -1.190  53.564  -7.607  1.00 51.21  ? 229 ASP C CB  1 
ATOM   8688  C  CG  . ASP C 1 229 ? -2.532  54.269  -7.719  1.00 55.95  ? 229 ASP C CG  1 
ATOM   8689  O  OD1 . ASP C 1 229 ? -3.573  53.601  -7.527  1.00 55.58  ? 229 ASP C OD1 1 
ATOM   8690  O  OD2 . ASP C 1 229 ? -2.543  55.488  -8.010  1.00 56.96  ? 229 ASP C OD2 1 
ATOM   8691  N  N   . MET C 1 230 ? -0.020  51.335  -9.422  1.00 35.31  ? 230 MET C N   1 
ATOM   8692  C  CA  . MET C 1 230 ? 1.188   50.920  -10.126 1.00 37.11  ? 230 MET C CA  1 
ATOM   8693  C  C   . MET C 1 230 ? 2.363   51.832  -9.798  1.00 37.54  ? 230 MET C C   1 
ATOM   8694  O  O   . MET C 1 230 ? 2.278   53.045  -9.996  1.00 38.09  ? 230 MET C O   1 
ATOM   8695  C  CB  . MET C 1 230 ? 0.966   50.977  -11.636 1.00 36.30  ? 230 MET C CB  1 
ATOM   8696  C  CG  . MET C 1 230 ? 1.960   50.178  -12.415 1.00 34.99  ? 230 MET C CG  1 
ATOM   8697  S  SD  . MET C 1 230 ? 1.294   49.522  -13.940 1.00 35.08  ? 230 MET C SD  1 
ATOM   8698  C  CE  . MET C 1 230 ? 0.780   47.858  -13.477 1.00 31.27  ? 230 MET C CE  1 
ATOM   8699  N  N   . THR C 1 231 ? 3.476   51.244  -9.349  1.00 38.70  ? 231 THR C N   1 
ATOM   8700  C  CA  . THR C 1 231 ? 4.726   51.988  -9.227  1.00 37.42  ? 231 THR C CA  1 
ATOM   8701  C  C   . THR C 1 231 ? 5.313   52.259  -10.612 1.00 34.32  ? 231 THR C C   1 
ATOM   8702  O  O   . THR C 1 231 ? 4.932   51.629  -11.605 1.00 38.36  ? 231 THR C O   1 
ATOM   8703  C  CB  . THR C 1 231 ? 5.729   51.233  -8.335  1.00 36.19  ? 231 THR C CB  1 
ATOM   8704  O  OG1 . THR C 1 231 ? 6.312   50.130  -9.038  1.00 34.04  ? 231 THR C OG1 1 
ATOM   8705  C  CG2 . THR C 1 231 ? 5.042   50.705  -7.090  1.00 40.55  ? 231 THR C CG2 1 
ATOM   8706  N  N   . VAL C 1 232 ? 6.240   53.225  -10.692 1.00 35.35  ? 232 VAL C N   1 
ATOM   8707  C  CA  . VAL C 1 232 ? 6.898   53.455  -11.982 1.00 37.76  ? 232 VAL C CA  1 
ATOM   8708  C  C   . VAL C 1 232 ? 7.709   52.225  -12.399 1.00 31.04  ? 232 VAL C C   1 
ATOM   8709  O  O   . VAL C 1 232 ? 7.693   51.813  -13.567 1.00 34.26  ? 232 VAL C O   1 
ATOM   8710  C  CB  . VAL C 1 232 ? 7.754   54.746  -11.967 1.00 36.73  ? 232 VAL C CB  1 
ATOM   8711  C  CG1 . VAL C 1 232 ? 6.937   55.939  -11.537 1.00 37.82  ? 232 VAL C CG1 1 
ATOM   8712  C  CG2 . VAL C 1 232 ? 8.956   54.617  -11.073 1.00 40.69  ? 232 VAL C CG2 1 
ATOM   8713  N  N   . GLU C 1 233 ? 8.379   51.586  -11.447 1.00 27.17  ? 233 GLU C N   1 
ATOM   8714  C  CA  . GLU C 1 233 ? 9.162   50.401  -11.770 1.00 33.14  ? 233 GLU C CA  1 
ATOM   8715  C  C   . GLU C 1 233 ? 8.290   49.239  -12.266 1.00 28.60  ? 233 GLU C C   1 
ATOM   8716  O  O   . GLU C 1 233 ? 8.777   48.373  -12.999 1.00 31.63  ? 233 GLU C O   1 
ATOM   8717  C  CB  . GLU C 1 233 ? 9.982   49.993  -10.537 1.00 33.27  ? 233 GLU C CB  1 
ATOM   8718  C  CG  . GLU C 1 233 ? 11.032  51.033  -10.107 1.00 33.98  ? 233 GLU C CG  1 
ATOM   8719  C  CD  . GLU C 1 233 ? 10.435  52.186  -9.296  1.00 39.18  ? 233 GLU C CD  1 
ATOM   8720  O  OE1 . GLU C 1 233 ? 9.366   52.010  -8.660  1.00 39.71  ? 233 GLU C OE1 1 
ATOM   8721  O  OE2 . GLU C 1 233 ? 11.038  53.272  -9.289  1.00 35.99  ? 233 GLU C OE2 1 
ATOM   8722  N  N   . GLU C 1 234 ? 7.016   49.196  -11.889 1.00 31.56  ? 234 GLU C N   1 
ATOM   8723  C  CA  . GLU C 1 234 ? 6.166   48.102  -12.349 1.00 35.92  ? 234 GLU C CA  1 
ATOM   8724  C  C   . GLU C 1 234 ? 5.598   48.383  -13.735 1.00 30.49  ? 234 GLU C C   1 
ATOM   8725  O  O   . GLU C 1 234 ? 5.534   47.481  -14.578 1.00 32.22  ? 234 GLU C O   1 
ATOM   8726  C  CB  . GLU C 1 234 ? 5.055   47.856  -11.333 1.00 32.31  ? 234 GLU C CB  1 
ATOM   8727  C  CG  . GLU C 1 234 ? 5.563   47.058  -10.106 1.00 39.84  ? 234 GLU C CG  1 
ATOM   8728  C  CD  . GLU C 1 234 ? 4.605   47.082  -8.940  1.00 34.24  ? 234 GLU C CD  1 
ATOM   8729  O  OE1 . GLU C 1 234 ? 3.580   47.794  -9.036  1.00 38.94  ? 234 GLU C OE1 1 
ATOM   8730  O  OE2 . GLU C 1 234 ? 4.889   46.397  -7.928  1.00 42.89  ? 234 GLU C OE2 1 
ATOM   8731  N  N   . GLY C 1 235 ? 5.174   49.625  -13.982 1.00 30.54  ? 235 GLY C N   1 
ATOM   8732  C  CA  . GLY C 1 235 ? 4.797   50.000  -15.333 1.00 27.74  ? 235 GLY C CA  1 
ATOM   8733  C  C   . GLY C 1 235 ? 5.932   49.806  -16.319 1.00 31.02  ? 235 GLY C C   1 
ATOM   8734  O  O   . GLY C 1 235 ? 5.720   49.335  -17.440 1.00 35.18  ? 235 GLY C O   1 
ATOM   8735  N  N   . ALA C 1 236 ? 7.162   50.137  -15.907 1.00 27.73  ? 236 ALA C N   1 
ATOM   8736  C  CA  . ALA C 1 236 ? 8.281   50.062  -16.845 1.00 31.91  ? 236 ALA C CA  1 
ATOM   8737  C  C   . ALA C 1 236 ? 8.671   48.621  -17.137 1.00 33.15  ? 236 ALA C C   1 
ATOM   8738  O  O   . ALA C 1 236 ? 9.105   48.302  -18.250 1.00 29.47  ? 236 ALA C O   1 
ATOM   8739  C  CB  . ALA C 1 236 ? 9.483   50.828  -16.304 1.00 34.61  ? 236 ALA C CB  1 
ATOM   8740  N  N   . ALA C 1 237 ? 8.566   47.748  -16.133 1.00 34.65  ? 237 ALA C N   1 
ATOM   8741  C  CA  . ALA C 1 237 ? 8.824   46.332  -16.354 1.00 30.44  ? 237 ALA C CA  1 
ATOM   8742  C  C   . ALA C 1 237 ? 7.824   45.749  -17.332 1.00 28.72  ? 237 ALA C C   1 
ATOM   8743  O  O   . ALA C 1 237 ? 8.172   44.888  -18.148 1.00 36.82  ? 237 ALA C O   1 
ATOM   8744  C  CB  . ALA C 1 237 ? 8.778   45.572  -15.026 1.00 27.19  ? 237 ALA C CB  1 
ATOM   8745  N  N   . ALA C 1 238 ? 6.567   46.198  -17.261 1.00 34.02  ? 238 ALA C N   1 
ATOM   8746  C  CA  . ALA C 1 238 ? 5.533   45.673  -18.152 1.00 31.09  ? 238 ALA C CA  1 
ATOM   8747  C  C   . ALA C 1 238 ? 5.769   46.117  -19.591 1.00 30.50  ? 238 ALA C C   1 
ATOM   8748  O  O   . ALA C 1 238 ? 5.851   45.286  -20.507 1.00 32.47  ? 238 ALA C O   1 
ATOM   8749  C  CB  . ALA C 1 238 ? 4.156   46.121  -17.670 1.00 32.86  ? 238 ALA C CB  1 
ATOM   8750  N  N   . LEU C 1 239 ? 5.880   47.427  -19.806 1.00 34.11  ? 239 LEU C N   1 
ATOM   8751  C  CA  . LEU C 1 239 ? 6.294   47.947  -21.109 1.00 27.08  ? 239 LEU C CA  1 
ATOM   8752  C  C   . LEU C 1 239 ? 7.545   47.238  -21.616 1.00 29.62  ? 239 LEU C C   1 
ATOM   8753  O  O   . LEU C 1 239 ? 7.608   46.852  -22.787 1.00 30.56  ? 239 LEU C O   1 
ATOM   8754  C  CB  . LEU C 1 239 ? 6.537   49.451  -21.011 1.00 29.67  ? 239 LEU C CB  1 
ATOM   8755  C  CG  . LEU C 1 239 ? 6.939   50.164  -22.306 1.00 34.31  ? 239 LEU C CG  1 
ATOM   8756  C  CD1 . LEU C 1 239 ? 5.974   49.748  -23.432 1.00 34.76  ? 239 LEU C CD1 1 
ATOM   8757  C  CD2 . LEU C 1 239 ? 6.952   51.657  -22.114 1.00 26.03  ? 239 LEU C CD2 1 
ATOM   8758  N  N   . GLN C 1 240 ? 8.555   47.059  -20.748 1.00 34.61  ? 240 GLN C N   1 
ATOM   8759  C  CA  . GLN C 1 240 ? 9.783   46.394  -21.179 1.00 31.44  ? 240 GLN C CA  1 
ATOM   8760  C  C   . GLN C 1 240 ? 9.497   44.972  -21.623 1.00 36.92  ? 240 GLN C C   1 
ATOM   8761  O  O   . GLN C 1 240 ? 10.022  44.514  -22.647 1.00 32.23  ? 240 GLN C O   1 
ATOM   8762  C  CB  . GLN C 1 240 ? 10.827  46.392  -20.063 1.00 33.75  ? 240 GLN C CB  1 
ATOM   8763  C  CG  . GLN C 1 240 ? 11.793  47.578  -20.048 1.00 33.68  ? 240 GLN C CG  1 
ATOM   8764  C  CD  . GLN C 1 240 ? 12.567  47.674  -18.731 1.00 41.62  ? 240 GLN C CD  1 
ATOM   8765  O  OE1 . GLN C 1 240 ? 13.043  46.663  -18.190 1.00 41.57  ? 240 GLN C OE1 1 
ATOM   8766  N  NE2 . GLN C 1 240 ? 12.674  48.890  -18.197 1.00 38.62  ? 240 GLN C NE2 1 
ATOM   8767  N  N   . ARG C 1 241 ? 8.654   44.262  -20.861 1.00 36.73  ? 241 ARG C N   1 
ATOM   8768  C  CA  . ARG C 1 241 ? 8.283   42.897  -21.209 1.00 28.91  ? 241 ARG C CA  1 
ATOM   8769  C  C   . ARG C 1 241 ? 7.569   42.850  -22.558 1.00 32.38  ? 241 ARG C C   1 
ATOM   8770  O  O   . ARG C 1 241 ? 7.764   41.914  -23.337 1.00 25.74  ? 241 ARG C O   1 
ATOM   8771  C  CB  . ARG C 1 241 ? 7.405   42.312  -20.098 1.00 33.07  ? 241 ARG C CB  1 
ATOM   8772  C  CG  . ARG C 1 241 ? 6.424   41.223  -20.525 1.00 36.93  ? 241 ARG C CG  1 
ATOM   8773  C  CD  . ARG C 1 241 ? 5.129   41.244  -19.678 1.00 39.37  ? 241 ARG C CD  1 
ATOM   8774  N  NE  . ARG C 1 241 ? 4.318   42.441  -19.901 1.00 38.21  ? 241 ARG C NE  1 
ATOM   8775  C  CZ  . ARG C 1 241 ? 3.302   42.819  -19.135 1.00 45.04  ? 241 ARG C CZ  1 
ATOM   8776  N  NH1 . ARG C 1 241 ? 2.983   42.155  -18.032 1.00 43.34  ? 241 ARG C NH1 1 
ATOM   8777  N  NH2 . ARG C 1 241 ? 2.584   43.888  -19.485 1.00 43.10  ? 241 ARG C NH2 1 
ATOM   8778  N  N   . ASP C 1 242 ? 6.770   43.877  -22.869 1.00 31.76  ? 242 ASP C N   1 
ATOM   8779  C  CA  . ASP C 1 242 ? 6.028   43.861  -24.124 1.00 33.41  ? 242 ASP C CA  1 
ATOM   8780  C  C   . ASP C 1 242 ? 6.901   44.294  -25.297 1.00 27.76  ? 242 ASP C C   1 
ATOM   8781  O  O   . ASP C 1 242 ? 6.712   43.810  -26.417 1.00 28.41  ? 242 ASP C O   1 
ATOM   8782  C  CB  . ASP C 1 242 ? 4.781   44.748  -24.017 1.00 32.35  ? 242 ASP C CB  1 
ATOM   8783  C  CG  . ASP C 1 242 ? 3.678   44.105  -23.191 1.00 33.70  ? 242 ASP C CG  1 
ATOM   8784  O  OD1 . ASP C 1 242 ? 3.556   42.874  -23.264 1.00 34.80  ? 242 ASP C OD1 1 
ATOM   8785  O  OD2 . ASP C 1 242 ? 2.931   44.818  -22.480 1.00 29.65  ? 242 ASP C OD2 1 
ATOM   8786  N  N   . LEU C 1 243 ? 7.860   45.192  -25.068 1.00 30.71  ? 243 LEU C N   1 
ATOM   8787  C  CA  . LEU C 1 243 ? 8.828   45.491  -26.122 1.00 33.96  ? 243 LEU C CA  1 
ATOM   8788  C  C   . LEU C 1 243 ? 9.583   44.234  -26.550 1.00 30.83  ? 243 LEU C C   1 
ATOM   8789  O  O   . LEU C 1 243 ? 9.753   43.981  -27.747 1.00 30.65  ? 243 LEU C O   1 
ATOM   8790  C  CB  . LEU C 1 243 ? 9.794   46.574  -25.645 1.00 38.80  ? 243 LEU C CB  1 
ATOM   8791  C  CG  . LEU C 1 243 ? 9.279   48.016  -25.762 1.00 34.71  ? 243 LEU C CG  1 
ATOM   8792  C  CD1 . LEU C 1 243 ? 9.954   48.919  -24.739 1.00 28.25  ? 243 LEU C CD1 1 
ATOM   8793  C  CD2 . LEU C 1 243 ? 9.509   48.527  -27.177 1.00 40.47  ? 243 LEU C CD2 1 
ATOM   8794  N  N   . ARG C 1 244 ? 10.000  43.402  -25.583 1.00 28.23  ? 244 ARG C N   1 
ATOM   8795  C  CA  . ARG C 1 244 ? 10.759  42.200  -25.917 1.00 28.66  ? 244 ARG C CA  1 
ATOM   8796  C  C   . ARG C 1 244 ? 9.890   41.175  -26.636 1.00 34.11  ? 244 ARG C C   1 
ATOM   8797  O  O   . ARG C 1 244 ? 10.352  40.485  -27.559 1.00 31.51  ? 244 ARG C O   1 
ATOM   8798  C  CB  . ARG C 1 244 ? 11.361  41.600  -24.653 1.00 32.13  ? 244 ARG C CB  1 
ATOM   8799  C  CG  . ARG C 1 244 ? 12.288  42.546  -23.910 1.00 29.61  ? 244 ARG C CG  1 
ATOM   8800  C  CD  . ARG C 1 244 ? 13.302  41.780  -23.081 1.00 33.43  ? 244 ARG C CD  1 
ATOM   8801  N  NE  . ARG C 1 244 ? 13.950  42.620  -22.076 1.00 35.55  ? 244 ARG C NE  1 
ATOM   8802  C  CZ  . ARG C 1 244 ? 13.403  42.971  -20.919 1.00 38.66  ? 244 ARG C CZ  1 
ATOM   8803  N  NH1 . ARG C 1 244 ? 12.190  42.563  -20.572 1.00 42.58  ? 244 ARG C NH1 1 
ATOM   8804  N  NH2 . ARG C 1 244 ? 14.093  43.742  -20.081 1.00 34.77  ? 244 ARG C NH2 1 
ATOM   8805  N  N   . LEU C 1 245 ? 8.634   41.036  -26.213 1.00 32.44  ? 245 LEU C N   1 
ATOM   8806  C  CA  . LEU C 1 245 ? 7.715   40.179  -26.950 1.00 35.87  ? 245 LEU C CA  1 
ATOM   8807  C  C   . LEU C 1 245 ? 7.504   40.709  -28.368 1.00 30.24  ? 245 LEU C C   1 
ATOM   8808  O  O   . LEU C 1 245 ? 7.578   39.956  -29.346 1.00 32.68  ? 245 LEU C O   1 
ATOM   8809  C  CB  . LEU C 1 245 ? 6.394   40.077  -26.192 1.00 29.79  ? 245 LEU C CB  1 
ATOM   8810  C  CG  . LEU C 1 245 ? 5.329   39.229  -26.871 1.00 29.71  ? 245 LEU C CG  1 
ATOM   8811  C  CD1 . LEU C 1 245 ? 5.762   37.764  -27.056 1.00 29.89  ? 245 LEU C CD1 1 
ATOM   8812  C  CD2 . LEU C 1 245 ? 4.078   39.318  -26.041 1.00 29.36  ? 245 LEU C CD2 1 
ATOM   8813  N  N   . ALA C 1 246 ? 7.237   42.010  -28.489 1.00 30.48  ? 246 ALA C N   1 
ATOM   8814  C  CA  . ALA C 1 246 ? 7.160   42.653  -29.796 1.00 30.09  ? 246 ALA C CA  1 
ATOM   8815  C  C   . ALA C 1 246 ? 8.374   42.326  -30.659 1.00 29.62  ? 246 ALA C C   1 
ATOM   8816  O  O   . ALA C 1 246 ? 8.234   41.880  -31.803 1.00 28.15  ? 246 ALA C O   1 
ATOM   8817  C  CB  . ALA C 1 246 ? 7.039   44.157  -29.619 1.00 27.38  ? 246 ALA C CB  1 
ATOM   8818  N  N   . LYS C 1 247 ? 9.577   42.545  -30.123 1.00 31.78  ? 247 LYS C N   1 
ATOM   8819  C  CA  . LYS C 1 247 ? 10.793  42.304  -30.898 1.00 30.38  ? 247 LYS C CA  1 
ATOM   8820  C  C   . LYS C 1 247 ? 10.918  40.844  -31.283 1.00 33.45  ? 247 LYS C C   1 
ATOM   8821  O  O   . LYS C 1 247 ? 11.343  40.518  -32.398 1.00 30.45  ? 247 LYS C O   1 
ATOM   8822  C  CB  . LYS C 1 247 ? 12.020  42.737  -30.103 1.00 31.92  ? 247 LYS C CB  1 
ATOM   8823  C  CG  . LYS C 1 247 ? 13.343  42.415  -30.772 1.00 29.19  ? 247 LYS C CG  1 
ATOM   8824  C  CD  . LYS C 1 247 ? 13.500  43.152  -32.066 1.00 34.39  ? 247 LYS C CD  1 
ATOM   8825  C  CE  . LYS C 1 247 ? 14.896  42.943  -32.666 1.00 37.90  ? 247 LYS C CE  1 
ATOM   8826  N  NZ  . LYS C 1 247 ? 14.971  43.533  -34.034 1.00 42.06  ? 247 LYS C NZ  1 
ATOM   8827  N  N   . ARG C 1 248 ? 10.565  39.945  -30.364 1.00 31.53  ? 248 ARG C N   1 
ATOM   8828  C  CA  . ARG C 1 248 ? 10.683  38.525  -30.656 1.00 30.90  ? 248 ARG C CA  1 
ATOM   8829  C  C   . ARG C 1 248 ? 9.776   38.124  -31.808 1.00 28.22  ? 248 ARG C C   1 
ATOM   8830  O  O   . ARG C 1 248 ? 10.136  37.268  -32.625 1.00 37.33  ? 248 ARG C O   1 
ATOM   8831  C  CB  . ARG C 1 248 ? 10.349  37.706  -29.411 1.00 26.74  ? 248 ARG C CB  1 
ATOM   8832  C  CG  . ARG C 1 248 ? 10.349  36.232  -29.683 1.00 31.68  ? 248 ARG C CG  1 
ATOM   8833  C  CD  . ARG C 1 248 ? 9.439   35.512  -28.716 1.00 36.36  ? 248 ARG C CD  1 
ATOM   8834  N  NE  . ARG C 1 248 ? 9.995   34.225  -28.336 1.00 35.26  ? 248 ARG C NE  1 
ATOM   8835  C  CZ  . ARG C 1 248 ? 9.560   33.496  -27.317 1.00 38.39  ? 248 ARG C CZ  1 
ATOM   8836  N  NH1 . ARG C 1 248 ? 8.561   33.900  -26.551 1.00 37.58  ? 248 ARG C NH1 1 
ATOM   8837  N  NH2 . ARG C 1 248 ? 10.146  32.336  -27.057 1.00 41.10  ? 248 ARG C NH2 1 
ATOM   8838  N  N   . LEU C 1 249 ? 8.580   38.699  -31.865 1.00 27.06  ? 249 LEU C N   1 
ATOM   8839  C  CA  . LEU C 1 249 ? 7.608   38.375  -32.902 1.00 27.48  ? 249 LEU C CA  1 
ATOM   8840  C  C   . LEU C 1 249 ? 7.803   39.203  -34.174 1.00 28.21  ? 249 LEU C C   1 
ATOM   8841  O  O   . LEU C 1 249 ? 7.030   39.051  -35.127 1.00 22.32  ? 249 LEU C O   1 
ATOM   8842  C  CB  . LEU C 1 249 ? 6.183   38.567  -32.351 1.00 28.60  ? 249 LEU C CB  1 
ATOM   8843  C  CG  . LEU C 1 249 ? 5.817   37.671  -31.146 1.00 26.91  ? 249 LEU C CG  1 
ATOM   8844  C  CD1 . LEU C 1 249 ? 4.331   37.774  -30.781 1.00 32.22  ? 249 LEU C CD1 1 
ATOM   8845  C  CD2 . LEU C 1 249 ? 6.174   36.239  -31.455 1.00 21.90  ? 249 LEU C CD2 1 
ATOM   8846  N  N   . GLY C 1 250 ? 8.797   40.086  -34.207 1.00 28.56  ? 250 GLY C N   1 
ATOM   8847  C  CA  . GLY C 1 250 ? 9.112   40.811  -35.427 1.00 29.01  ? 250 GLY C CA  1 
ATOM   8848  C  C   . GLY C 1 250 ? 8.480   42.174  -35.595 1.00 29.57  ? 250 GLY C C   1 
ATOM   8849  O  O   . GLY C 1 250 ? 8.562   42.738  -36.692 1.00 32.64  ? 250 GLY C O   1 
ATOM   8850  N  N   . PHE C 1 251 ? 7.910   42.757  -34.545 1.00 28.68  ? 251 PHE C N   1 
ATOM   8851  C  CA  . PHE C 1 251 ? 7.154   43.992  -34.717 1.00 30.22  ? 251 PHE C CA  1 
ATOM   8852  C  C   . PHE C 1 251 ? 8.080   45.207  -34.721 1.00 31.74  ? 251 PHE C C   1 
ATOM   8853  O  O   . PHE C 1 251 ? 9.118   45.234  -34.050 1.00 29.97  ? 251 PHE C O   1 
ATOM   8854  C  CB  . PHE C 1 251 ? 6.073   44.126  -33.628 1.00 30.06  ? 251 PHE C CB  1 
ATOM   8855  C  CG  . PHE C 1 251 ? 4.871   43.218  -33.839 1.00 25.86  ? 251 PHE C CG  1 
ATOM   8856  C  CD1 . PHE C 1 251 ? 4.880   41.905  -33.387 1.00 29.79  ? 251 PHE C CD1 1 
ATOM   8857  C  CD2 . PHE C 1 251 ? 3.735   43.684  -34.479 1.00 25.10  ? 251 PHE C CD2 1 
ATOM   8858  C  CE1 . PHE C 1 251 ? 3.789   41.081  -33.574 1.00 22.57  ? 251 PHE C CE1 1 
ATOM   8859  C  CE2 . PHE C 1 251 ? 2.645   42.877  -34.689 1.00 24.37  ? 251 PHE C CE2 1 
ATOM   8860  C  CZ  . PHE C 1 251 ? 2.662   41.562  -34.237 1.00 27.14  ? 251 PHE C CZ  1 
ATOM   8861  N  N   . ARG C 1 252 ? 7.684   46.214  -35.491 1.00 30.79  ? 252 ARG C N   1 
ATOM   8862  C  CA  . ARG C 1 252 ? 8.439   47.483  -35.519 1.00 31.03  ? 252 ARG C CA  1 
ATOM   8863  C  C   . ARG C 1 252 ? 7.943   48.578  -34.461 1.00 34.91  ? 252 ARG C C   1 
ATOM   8864  O  O   . ARG C 1 252 ? 8.610   49.597  -34.041 1.00 31.33  ? 252 ARG C O   1 
ATOM   8865  C  CB  . ARG C 1 252 ? 8.404   48.118  -36.924 1.00 26.32  ? 252 ARG C CB  1 
ATOM   8866  C  CG  . ARG C 1 252 ? 9.185   47.332  -37.968 1.00 39.99  ? 252 ARG C CG  1 
ATOM   8867  C  CD  . ARG C 1 252 ? 8.706   47.597  -39.408 1.00 42.19  ? 252 ARG C CD  1 
ATOM   8868  N  NE  . ARG C 1 252 ? 8.462   49.013  -39.672 1.00 43.43  ? 252 ARG C NE  1 
ATOM   8869  C  CZ  . ARG C 1 252 ? 7.664   49.472  -40.630 1.00 50.60  ? 252 ARG C CZ  1 
ATOM   8870  N  NH1 . ARG C 1 252 ? 7.009   48.649  -41.441 1.00 45.94  ? 252 ARG C NH1 1 
ATOM   8871  N  NH2 . ARG C 1 252 ? 7.511   50.789  -40.776 1.00 52.76  ? 252 ARG C NH2 1 
ATOM   8872  N  N   . PHE C 1 253 ? 6.698   48.372  -34.011 1.00 29.86  ? 253 PHE C N   1 
ATOM   8873  C  CA  . PHE C 1 253 ? 6.113   49.338  -33.091 1.00 30.70  ? 253 PHE C CA  1 
ATOM   8874  C  C   . PHE C 1 253 ? 5.412   48.633  -31.923 1.00 30.12  ? 253 PHE C C   1 
ATOM   8875  O  O   . PHE C 1 253 ? 4.936   47.501  -32.054 1.00 31.71  ? 253 PHE C O   1 
ATOM   8876  C  CB  . PHE C 1 253 ? 5.084   50.248  -33.807 1.00 28.04  ? 253 PHE C CB  1 
ATOM   8877  C  CG  . PHE C 1 253 ? 5.593   50.902  -35.077 1.00 29.63  ? 253 PHE C CG  1 
ATOM   8878  C  CD1 . PHE C 1 253 ? 6.509   51.941  -35.032 1.00 35.54  ? 253 PHE C CD1 1 
ATOM   8879  C  CD2 . PHE C 1 253 ? 5.145   50.472  -36.316 1.00 31.90  ? 253 PHE C CD2 1 
ATOM   8880  C  CE1 . PHE C 1 253 ? 6.967   52.553  -36.217 1.00 36.76  ? 253 PHE C CE1 1 
ATOM   8881  C  CE2 . PHE C 1 253 ? 5.597   51.072  -37.497 1.00 34.19  ? 253 PHE C CE2 1 
ATOM   8882  C  CZ  . PHE C 1 253 ? 6.507   52.106  -37.444 1.00 30.62  ? 253 PHE C CZ  1 
ATOM   8883  N  N   . VAL C 1 254 ? 5.352   49.319  -30.780 1.00 29.48  ? 254 VAL C N   1 
ATOM   8884  C  CA  . VAL C 1 254 ? 4.456   48.967  -29.681 1.00 34.84  ? 254 VAL C CA  1 
ATOM   8885  C  C   . VAL C 1 254 ? 3.696   50.215  -29.254 1.00 27.76  ? 254 VAL C C   1 
ATOM   8886  O  O   . VAL C 1 254 ? 4.293   51.278  -29.070 1.00 35.06  ? 254 VAL C O   1 
ATOM   8887  C  CB  . VAL C 1 254 ? 5.179   48.347  -28.463 1.00 35.36  ? 254 VAL C CB  1 
ATOM   8888  C  CG1 . VAL C 1 254 ? 5.878   47.123  -28.863 1.00 29.51  ? 254 VAL C CG1 1 
ATOM   8889  C  CG2 . VAL C 1 254 ? 6.146   49.317  -27.803 1.00 35.86  ? 254 VAL C CG2 1 
ATOM   8890  N  N   . ARG C 1 255 ? 2.372   50.080  -29.119 1.00 30.93  ? 255 ARG C N   1 
ATOM   8891  C  CA  . ARG C 1 255 ? 1.458   51.092  -28.613 1.00 27.16  ? 255 ARG C CA  1 
ATOM   8892  C  C   . ARG C 1 255 ? 1.067   50.747  -27.182 1.00 35.46  ? 255 ARG C C   1 
ATOM   8893  O  O   . ARG C 1 255 ? 0.155   49.928  -26.978 1.00 33.87  ? 255 ARG C O   1 
ATOM   8894  C  CB  . ARG C 1 255 ? 0.218   51.151  -29.498 1.00 24.64  ? 255 ARG C CB  1 
ATOM   8895  C  CG  . ARG C 1 255 ? -0.845  52.108  -29.052 1.00 32.39  ? 255 ARG C CG  1 
ATOM   8896  C  CD  . ARG C 1 255 ? -2.198  51.466  -29.206 1.00 31.79  ? 255 ARG C CD  1 
ATOM   8897  N  NE  . ARG C 1 255 ? -2.417  50.490  -28.142 1.00 35.86  ? 255 ARG C NE  1 
ATOM   8898  C  CZ  . ARG C 1 255 ? -3.604  49.973  -27.853 1.00 34.86  ? 255 ARG C CZ  1 
ATOM   8899  N  NH1 . ARG C 1 255 ? -4.690  50.332  -28.521 1.00 33.95  ? 255 ARG C NH1 1 
ATOM   8900  N  NH2 . ARG C 1 255 ? -3.703  49.073  -26.872 1.00 32.65  ? 255 ARG C NH2 1 
ATOM   8901  N  N   . PRO C 1 256 ? 1.694   51.348  -26.161 1.00 39.01  ? 256 PRO C N   1 
ATOM   8902  C  CA  . PRO C 1 256 ? 1.239   51.175  -24.774 1.00 34.60  ? 256 PRO C CA  1 
ATOM   8903  C  C   . PRO C 1 256 ? 0.002   52.016  -24.510 1.00 38.03  ? 256 PRO C C   1 
ATOM   8904  O  O   . PRO C 1 256 ? 0.055   53.252  -24.507 1.00 39.88  ? 256 PRO C O   1 
ATOM   8905  C  CB  . PRO C 1 256 ? 2.442   51.661  -23.954 1.00 34.34  ? 256 PRO C CB  1 
ATOM   8906  C  CG  . PRO C 1 256 ? 3.037   52.746  -24.813 1.00 35.23  ? 256 PRO C CG  1 
ATOM   8907  C  CD  . PRO C 1 256 ? 2.805   52.310  -26.259 1.00 35.50  ? 256 PRO C CD  1 
ATOM   8908  N  N   . LYS C 1 257 ? -1.123  51.344  -24.304 1.00 31.96  ? 257 LYS C N   1 
ATOM   8909  C  CA  . LYS C 1 257 ? -2.345  51.997  -23.861 1.00 35.65  ? 257 LYS C CA  1 
ATOM   8910  C  C   . LYS C 1 257 ? -2.221  52.234  -22.360 1.00 34.93  ? 257 LYS C C   1 
ATOM   8911  O  O   . LYS C 1 257 ? -2.420  51.319  -21.554 1.00 27.76  ? 257 LYS C O   1 
ATOM   8912  C  CB  . LYS C 1 257 ? -3.558  51.140  -24.199 1.00 29.76  ? 257 LYS C CB  1 
ATOM   8913  C  CG  . LYS C 1 257 ? -4.898  51.812  -23.877 1.00 35.99  ? 257 LYS C CG  1 
ATOM   8914  C  CD  . LYS C 1 257 ? -4.988  53.199  -24.498 1.00 34.93  ? 257 LYS C CD  1 
ATOM   8915  C  CE  . LYS C 1 257 ? -5.345  53.089  -25.975 1.00 27.36  ? 257 LYS C CE  1 
ATOM   8916  N  NZ  . LYS C 1 257 ? -6.112  54.265  -26.456 1.00 33.78  ? 257 LYS C NZ  1 
ATOM   8917  N  N   . ILE C 1 258 ? -1.899  53.471  -21.987 1.00 32.43  ? 258 ILE C N   1 
ATOM   8918  C  CA  . ILE C 1 258 ? -1.653  53.840  -20.600 1.00 35.06  ? 258 ILE C CA  1 
ATOM   8919  C  C   . ILE C 1 258 ? -2.969  54.140  -19.887 1.00 37.73  ? 258 ILE C C   1 
ATOM   8920  O  O   . ILE C 1 258 ? -3.964  54.542  -20.504 1.00 37.45  ? 258 ILE C O   1 
ATOM   8921  C  CB  . ILE C 1 258 ? -0.688  55.041  -20.566 1.00 41.36  ? 258 ILE C CB  1 
ATOM   8922  C  CG1 . ILE C 1 258 ? 0.389   54.862  -21.661 1.00 42.24  ? 258 ILE C CG1 1 
ATOM   8923  C  CG2 . ILE C 1 258 ? -0.082  55.195  -19.190 1.00 38.35  ? 258 ILE C CG2 1 
ATOM   8924  C  CD1 . ILE C 1 258 ? 1.534   55.879  -21.616 1.00 46.17  ? 258 ILE C CD1 1 
ATOM   8925  N  N   . GLY C 1 259 ? -2.985  53.924  -18.570 1.00 41.35  ? 259 GLY C N   1 
ATOM   8926  C  CA  . GLY C 1 259 ? -4.171  54.241  -17.769 1.00 37.91  ? 259 GLY C CA  1 
ATOM   8927  C  C   . GLY C 1 259 ? -4.329  55.744  -17.537 1.00 35.82  ? 259 GLY C C   1 
ATOM   8928  O  O   . GLY C 1 259 ? -3.359  56.472  -17.347 1.00 35.34  ? 259 GLY C O   1 
ATOM   8929  N  N   . VAL C 1 260 ? -5.584  56.187  -17.520 1.00 37.18  ? 260 VAL C N   1 
ATOM   8930  C  CA  . VAL C 1 260 ? -5.946  57.595  -17.495 1.00 40.76  ? 260 VAL C CA  1 
ATOM   8931  C  C   . VAL C 1 260 ? -6.375  58.016  -16.097 1.00 45.15  ? 260 VAL C C   1 
ATOM   8932  O  O   . VAL C 1 260 ? -6.726  57.192  -15.248 1.00 44.97  ? 260 VAL C O   1 
ATOM   8933  C  CB  . VAL C 1 260 ? -7.076  57.881  -18.503 1.00 40.84  ? 260 VAL C CB  1 
ATOM   8934  C  CG1 . VAL C 1 260 ? -6.708  57.343  -19.871 1.00 46.23  ? 260 VAL C CG1 1 
ATOM   8935  C  CG2 . VAL C 1 260 ? -8.356  57.239  -18.013 1.00 43.13  ? 260 VAL C CG2 1 
ATOM   8936  N  N   . VAL C 1 261 ? -6.393  59.336  -15.863 1.00 49.48  ? 261 VAL C N   1 
ATOM   8937  C  CA  . VAL C 1 261 ? -6.869  59.890  -14.594 1.00 46.19  ? 261 VAL C CA  1 
ATOM   8938  C  C   . VAL C 1 261 ? -7.808  61.073  -14.814 1.00 50.52  ? 261 VAL C C   1 
ATOM   8939  O  O   . VAL C 1 261 ? -8.176  61.772  -13.862 1.00 54.36  ? 261 VAL C O   1 
ATOM   8940  C  CB  . VAL C 1 261 ? -5.693  60.300  -13.689 1.00 48.80  ? 261 VAL C CB  1 
ATOM   8941  C  CG1 . VAL C 1 261 ? -4.931  59.066  -13.196 1.00 42.56  ? 261 VAL C CG1 1 
ATOM   8942  C  CG2 . VAL C 1 261 ? -4.765  61.272  -14.425 1.00 49.68  ? 261 VAL C CG2 1 
ATOM   8943  N  N   . SER C 1 262 ? -8.209  61.305  -16.061 1.00 49.55  ? 262 SER C N   1 
ATOM   8944  C  CA  . SER C 1 262 ? -9.088  62.419  -16.388 1.00 58.46  ? 262 SER C CA  1 
ATOM   8945  C  C   . SER C 1 262 ? -10.006 62.005  -17.525 1.00 60.45  ? 262 SER C C   1 
ATOM   8946  O  O   . SER C 1 262 ? -9.740  61.039  -18.249 1.00 57.97  ? 262 SER C O   1 
ATOM   8947  C  CB  . SER C 1 262 ? -8.306  63.683  -16.781 1.00 57.93  ? 262 SER C CB  1 
ATOM   8948  O  OG  . SER C 1 262 ? -8.574  64.755  -15.891 1.00 61.01  ? 262 SER C OG  1 
ATOM   8949  N  N   . SER C 1 263 ? -11.090 62.764  -17.684 1.00 56.15  ? 263 SER C N   1 
ATOM   8950  C  CA  . SER C 1 263 ? -12.086 62.452  -18.699 1.00 55.18  ? 263 SER C CA  1 
ATOM   8951  C  C   . SER C 1 263 ? -11.639 62.818  -20.112 1.00 59.30  ? 263 SER C C   1 
ATOM   8952  O  O   . SER C 1 263 ? -12.244 62.331  -21.077 1.00 65.84  ? 263 SER C O   1 
ATOM   8953  C  CB  . SER C 1 263 ? -13.394 63.153  -18.356 1.00 51.69  ? 263 SER C CB  1 
ATOM   8954  O  OG  . SER C 1 263 ? -13.349 63.610  -17.019 1.00 53.50  ? 263 SER C OG  1 
ATOM   8955  N  N   . ASP C 1 264 ? -10.601 63.649  -20.267 1.00 63.76  ? 264 ASP C N   1 
ATOM   8956  C  CA  . ASP C 1 264 ? -10.000 63.869  -21.580 1.00 62.53  ? 264 ASP C CA  1 
ATOM   8957  C  C   . ASP C 1 264 ? -8.794  62.960  -21.823 1.00 64.76  ? 264 ASP C C   1 
ATOM   8958  O  O   . ASP C 1 264 ? -7.979  63.248  -22.711 1.00 62.65  ? 264 ASP C O   1 
ATOM   8959  C  CB  . ASP C 1 264 ? -9.626  65.349  -21.789 1.00 63.37  ? 264 ASP C CB  1 
ATOM   8960  C  CG  . ASP C 1 264 ? -8.838  65.964  -20.624 1.00 67.66  ? 264 ASP C CG  1 
ATOM   8961  O  OD1 . ASP C 1 264 ? -8.903  65.453  -19.480 1.00 63.52  ? 264 ASP C OD1 1 
ATOM   8962  O  OD2 . ASP C 1 264 ? -8.171  67.004  -20.872 1.00 54.00  ? 264 ASP C OD2 1 
ATOM   8963  N  N   . LEU C 1 265 ? -8.678  61.872  -21.044 1.00 60.91  ? 265 LEU C N   1 
ATOM   8964  C  CA  . LEU C 1 265 ? -7.722  60.778  -21.252 1.00 55.05  ? 265 LEU C CA  1 
ATOM   8965  C  C   . LEU C 1 265 ? -6.285  61.168  -20.883 1.00 55.68  ? 265 LEU C C   1 
ATOM   8966  O  O   . LEU C 1 265 ? -5.328  60.709  -21.515 1.00 53.93  ? 265 LEU C O   1 
ATOM   8967  C  CB  . LEU C 1 265 ? -7.786  60.231  -22.690 1.00 57.34  ? 265 LEU C CB  1 
ATOM   8968  C  CG  . LEU C 1 265 ? -9.068  59.573  -23.253 1.00 54.19  ? 265 LEU C CG  1 
ATOM   8969  C  CD1 . LEU C 1 265 ? -8.737  58.713  -24.479 1.00 54.65  ? 265 LEU C CD1 1 
ATOM   8970  C  CD2 . LEU C 1 265 ? -9.835  58.741  -22.222 1.00 52.48  ? 265 LEU C CD2 1 
ATOM   8971  N  N   . ILE C 1 266 ? -6.123  61.995  -19.852 1.00 51.50  ? 266 ILE C N   1 
ATOM   8972  C  CA  . ILE C 1 266 ? -4.815  62.348  -19.300 1.00 54.74  ? 266 ILE C CA  1 
ATOM   8973  C  C   . ILE C 1 266 ? -4.127  61.088  -18.777 1.00 51.52  ? 266 ILE C C   1 
ATOM   8974  O  O   . ILE C 1 266 ? -4.701  60.382  -17.938 1.00 49.52  ? 266 ILE C O   1 
ATOM   8975  C  CB  . ILE C 1 266 ? -4.961  63.395  -18.181 1.00 56.51  ? 266 ILE C CB  1 
ATOM   8976  C  CG1 . ILE C 1 266 ? -5.409  64.745  -18.750 1.00 58.73  ? 266 ILE C CG1 1 
ATOM   8977  C  CG2 . ILE C 1 266 ? -3.665  63.528  -17.398 1.00 52.59  ? 266 ILE C CG2 1 
ATOM   8978  C  CD1 . ILE C 1 266 ? -4.337  65.459  -19.540 1.00 51.41  ? 266 ILE C CD1 1 
ATOM   8979  N  N   . PRO C 1 267 ? -2.924  60.753  -19.240 1.00 52.75  ? 267 PRO C N   1 
ATOM   8980  C  CA  . PRO C 1 267 ? -2.250  59.552  -18.723 1.00 49.20  ? 267 PRO C CA  1 
ATOM   8981  C  C   . PRO C 1 267 ? -1.894  59.678  -17.250 1.00 49.40  ? 267 PRO C C   1 
ATOM   8982  O  O   . PRO C 1 267 ? -1.710  60.774  -16.719 1.00 51.98  ? 267 PRO C O   1 
ATOM   8983  C  CB  . PRO C 1 267 ? -0.982  59.435  -19.581 1.00 48.24  ? 267 PRO C CB  1 
ATOM   8984  C  CG  . PRO C 1 267 ? -1.145  60.383  -20.719 1.00 52.68  ? 267 PRO C CG  1 
ATOM   8985  C  CD  . PRO C 1 267 ? -2.324  61.267  -20.485 1.00 52.92  ? 267 PRO C CD  1 
ATOM   8986  N  N   . HIS C 1 268 ? -1.805  58.529  -16.590 1.00 44.80  ? 268 HIS C N   1 
ATOM   8987  C  CA  . HIS C 1 268 ? -1.384  58.502  -15.202 1.00 42.08  ? 268 HIS C CA  1 
ATOM   8988  C  C   . HIS C 1 268 ? 0.035   59.052  -15.075 1.00 44.98  ? 268 HIS C C   1 
ATOM   8989  O  O   . HIS C 1 268 ? 0.880   58.794  -15.944 1.00 43.45  ? 268 HIS C O   1 
ATOM   8990  C  CB  . HIS C 1 268 ? -1.452  57.075  -14.656 1.00 46.30  ? 268 HIS C CB  1 
ATOM   8991  C  CG  . HIS C 1 268 ? -1.263  56.989  -13.174 1.00 40.37  ? 268 HIS C CG  1 
ATOM   8992  N  ND1 . HIS C 1 268 ? -0.040  57.180  -12.569 1.00 39.51  ? 268 HIS C ND1 1 
ATOM   8993  C  CD2 . HIS C 1 268 ? -2.143  56.731  -12.177 1.00 41.59  ? 268 HIS C CD2 1 
ATOM   8994  C  CE1 . HIS C 1 268 ? -0.175  57.044  -11.261 1.00 47.62  ? 268 HIS C CE1 1 
ATOM   8995  N  NE2 . HIS C 1 268 ? -1.442  56.769  -10.997 1.00 41.63  ? 268 HIS C NE2 1 
ATOM   8996  N  N   . PRO C 1 269 ? 0.331   59.800  -14.005 1.00 45.27  ? 269 PRO C N   1 
ATOM   8997  C  CA  . PRO C 1 269 ? 1.629   60.492  -13.901 1.00 43.42  ? 269 PRO C CA  1 
ATOM   8998  C  C   . PRO C 1 269 ? 2.868   59.611  -13.986 1.00 39.88  ? 269 PRO C C   1 
ATOM   8999  O  O   . PRO C 1 269 ? 3.956   60.143  -14.234 1.00 41.81  ? 269 PRO C O   1 
ATOM   9000  C  CB  . PRO C 1 269 ? 1.539   61.174  -12.533 1.00 47.52  ? 269 PRO C CB  1 
ATOM   9001  C  CG  . PRO C 1 269 ? 0.086   61.444  -12.375 1.00 51.75  ? 269 PRO C CG  1 
ATOM   9002  C  CD  . PRO C 1 269 ? -0.629  60.283  -12.999 1.00 44.51  ? 269 PRO C CD  1 
ATOM   9003  N  N   . ILE C 1 270 ? 2.772   58.296  -13.782 1.00 41.24  ? 270 ILE C N   1 
ATOM   9004  C  CA  . ILE C 1 270 ? 3.963   57.464  -13.956 1.00 40.18  ? 270 ILE C CA  1 
ATOM   9005  C  C   . ILE C 1 270 ? 4.354   57.278  -15.423 1.00 42.58  ? 270 ILE C C   1 
ATOM   9006  O  O   . ILE C 1 270 ? 5.456   56.789  -15.711 1.00 39.82  ? 270 ILE C O   1 
ATOM   9007  C  CB  . ILE C 1 270 ? 3.777   56.078  -13.304 1.00 36.56  ? 270 ILE C CB  1 
ATOM   9008  C  CG1 . ILE C 1 270 ? 2.767   55.251  -14.075 1.00 33.79  ? 270 ILE C CG1 1 
ATOM   9009  C  CG2 . ILE C 1 270 ? 3.266   56.220  -11.920 1.00 41.02  ? 270 ILE C CG2 1 
ATOM   9010  C  CD1 . ILE C 1 270 ? 2.743   53.820  -13.642 1.00 29.52  ? 270 ILE C CD1 1 
ATOM   9011  N  N   . TRP C 1 271 ? 3.494   57.673  -16.366 1.00 36.54  ? 271 TRP C N   1 
ATOM   9012  C  CA  . TRP C 1 271 ? 3.743   57.354  -17.769 1.00 37.24  ? 271 TRP C CA  1 
ATOM   9013  C  C   . TRP C 1 271 ? 5.085   57.889  -18.256 1.00 39.19  ? 271 TRP C C   1 
ATOM   9014  O  O   . TRP C 1 271 ? 5.735   57.245  -19.083 1.00 36.98  ? 271 TRP C O   1 
ATOM   9015  C  CB  . TRP C 1 271 ? 2.599   57.877  -18.642 1.00 42.12  ? 271 TRP C CB  1 
ATOM   9016  C  CG  . TRP C 1 271 ? 2.781   59.273  -19.087 1.00 44.23  ? 271 TRP C CG  1 
ATOM   9017  C  CD1 . TRP C 1 271 ? 2.336   60.397  -18.457 1.00 44.05  ? 271 TRP C CD1 1 
ATOM   9018  C  CD2 . TRP C 1 271 ? 3.475   59.717  -20.265 1.00 46.93  ? 271 TRP C CD2 1 
ATOM   9019  N  NE1 . TRP C 1 271 ? 2.714   61.518  -19.167 1.00 48.64  ? 271 TRP C NE1 1 
ATOM   9020  C  CE2 . TRP C 1 271 ? 3.415   61.128  -20.278 1.00 46.07  ? 271 TRP C CE2 1 
ATOM   9021  C  CE3 . TRP C 1 271 ? 4.149   59.059  -21.299 1.00 43.37  ? 271 TRP C CE3 1 
ATOM   9022  C  CZ2 . TRP C 1 271 ? 3.998   61.896  -21.293 1.00 55.85  ? 271 TRP C CZ2 1 
ATOM   9023  C  CZ3 . TRP C 1 271 ? 4.726   59.819  -22.309 1.00 53.21  ? 271 TRP C CZ3 1 
ATOM   9024  C  CH2 . TRP C 1 271 ? 4.647   61.226  -22.298 1.00 54.17  ? 271 TRP C CH2 1 
ATOM   9025  N  N   . THR C 1 272 ? 5.541   59.026  -17.727 1.00 38.39  ? 272 THR C N   1 
ATOM   9026  C  CA  . THR C 1 272 ? 6.746   59.663  -18.261 1.00 46.55  ? 272 THR C CA  1 
ATOM   9027  C  C   . THR C 1 272 ? 8.002   58.879  -17.896 1.00 39.91  ? 272 THR C C   1 
ATOM   9028  O  O   . THR C 1 272 ? 8.822   58.564  -18.765 1.00 40.23  ? 272 THR C O   1 
ATOM   9029  C  CB  . THR C 1 272 ? 6.839   61.110  -17.763 1.00 42.19  ? 272 THR C CB  1 
ATOM   9030  O  OG1 . THR C 1 272 ? 5.937   61.914  -18.523 1.00 38.55  ? 272 THR C OG1 1 
ATOM   9031  C  CG2 . THR C 1 272 ? 8.245   61.667  -17.929 1.00 39.56  ? 272 THR C CG2 1 
ATOM   9032  N  N   . GLU C 1 273 ? 8.177   58.558  -16.613 1.00 39.57  ? 273 GLU C N   1 
ATOM   9033  C  CA  . GLU C 1 273 ? 9.366   57.811  -16.220 1.00 37.32  ? 273 GLU C CA  1 
ATOM   9034  C  C   . GLU C 1 273 ? 9.272   56.357  -16.652 1.00 36.70  ? 273 GLU C C   1 
ATOM   9035  O  O   . GLU C 1 273 ? 10.305  55.699  -16.832 1.00 33.48  ? 273 GLU C O   1 
ATOM   9036  C  CB  . GLU C 1 273 ? 9.586   57.905  -14.712 1.00 37.65  ? 273 GLU C CB  1 
ATOM   9037  C  CG  . GLU C 1 273 ? 9.190   59.243  -14.092 1.00 43.47  ? 273 GLU C CG  1 
ATOM   9038  C  CD  . GLU C 1 273 ? 7.702   59.333  -13.722 1.00 50.63  ? 273 GLU C CD  1 
ATOM   9039  O  OE1 . GLU C 1 273 ? 7.394   59.257  -12.507 1.00 53.18  ? 273 GLU C OE1 1 
ATOM   9040  O  OE2 . GLU C 1 273 ? 6.850   59.525  -14.629 1.00 48.78  ? 273 GLU C OE2 1 
ATOM   9041  N  N   . VAL C 1 274 ? 8.048   55.838  -16.796 1.00 37.77  ? 274 VAL C N   1 
ATOM   9042  C  CA  . VAL C 1 274 ? 7.859   54.504  -17.363 1.00 32.93  ? 274 VAL C CA  1 
ATOM   9043  C  C   . VAL C 1 274 ? 8.484   54.424  -18.754 1.00 32.32  ? 274 VAL C C   1 
ATOM   9044  O  O   . VAL C 1 274 ? 9.223   53.484  -19.067 1.00 32.16  ? 274 VAL C O   1 
ATOM   9045  C  CB  . VAL C 1 274 ? 6.362   54.141  -17.376 1.00 31.84  ? 274 VAL C CB  1 
ATOM   9046  C  CG1 . VAL C 1 274 ? 6.084   53.075  -18.414 1.00 35.12  ? 274 VAL C CG1 1 
ATOM   9047  C  CG2 . VAL C 1 274 ? 5.920   53.644  -15.997 1.00 32.73  ? 274 VAL C CG2 1 
ATOM   9048  N  N   . VAL C 1 275 ? 8.233   55.440  -19.595 1.00 37.13  ? 275 VAL C N   1 
ATOM   9049  C  CA  . VAL C 1 275 ? 8.760   55.459  -20.963 1.00 33.57  ? 275 VAL C CA  1 
ATOM   9050  C  C   . VAL C 1 275 ? 10.255  55.777  -20.979 1.00 32.52  ? 275 VAL C C   1 
ATOM   9051  O  O   . VAL C 1 275 ? 11.022  55.173  -21.733 1.00 33.91  ? 275 VAL C O   1 
ATOM   9052  C  CB  . VAL C 1 275 ? 7.981   56.466  -21.833 1.00 37.57  ? 275 VAL C CB  1 
ATOM   9053  C  CG1 . VAL C 1 275 ? 8.584   56.525  -23.240 1.00 36.04  ? 275 VAL C CG1 1 
ATOM   9054  C  CG2 . VAL C 1 275 ? 6.526   56.105  -21.903 1.00 35.64  ? 275 VAL C CG2 1 
ATOM   9055  N  N   . GLU C 1 276 ? 10.691  56.749  -20.180 1.00 35.23  ? 276 GLU C N   1 
ATOM   9056  C  CA  . GLU C 1 276 ? 12.110  57.085  -20.166 1.00 37.88  ? 276 GLU C CA  1 
ATOM   9057  C  C   . GLU C 1 276 ? 12.942  55.909  -19.681 1.00 37.14  ? 276 GLU C C   1 
ATOM   9058  O  O   . GLU C 1 276 ? 14.048  55.668  -20.184 1.00 37.05  ? 276 GLU C O   1 
ATOM   9059  C  CB  . GLU C 1 276 ? 12.348  58.320  -19.299 1.00 37.45  ? 276 GLU C CB  1 
ATOM   9060  C  CG  . GLU C 1 276 ? 11.587  59.516  -19.813 1.00 46.75  ? 276 GLU C CG  1 
ATOM   9061  C  CD  . GLU C 1 276 ? 12.324  60.825  -19.617 1.00 46.92  ? 276 GLU C CD  1 
ATOM   9062  O  OE1 . GLU C 1 276 ? 13.564  60.844  -19.798 1.00 49.91  ? 276 GLU C OE1 1 
ATOM   9063  O  OE2 . GLU C 1 276 ? 11.654  61.828  -19.289 1.00 46.53  ? 276 GLU C OE2 1 
ATOM   9064  N  N   . ALA C 1 277 ? 12.418  55.144  -18.720 1.00 34.88  ? 277 ALA C N   1 
ATOM   9065  C  CA  . ALA C 1 277 ? 13.121  53.950  -18.282 1.00 27.45  ? 277 ALA C CA  1 
ATOM   9066  C  C   . ALA C 1 277 ? 13.066  52.846  -19.322 1.00 32.20  ? 277 ALA C C   1 
ATOM   9067  O  O   . ALA C 1 277 ? 13.831  51.886  -19.228 1.00 38.90  ? 277 ALA C O   1 
ATOM   9068  C  CB  . ALA C 1 277 ? 12.532  53.452  -16.973 1.00 31.68  ? 277 ALA C CB  1 
ATOM   9069  N  N   . SER C 1 278 ? 12.169  52.955  -20.296 1.00 29.38  ? 278 SER C N   1 
ATOM   9070  C  CA  . SER C 1 278 ? 11.987  51.944  -21.322 1.00 29.84  ? 278 SER C CA  1 
ATOM   9071  C  C   . SER C 1 278 ? 12.598  52.331  -22.664 1.00 33.27  ? 278 SER C C   1 
ATOM   9072  O  O   . SER C 1 278 ? 12.706  51.473  -23.547 1.00 36.74  ? 278 SER C O   1 
ATOM   9073  C  CB  . SER C 1 278 ? 10.488  51.659  -21.506 1.00 35.19  ? 278 SER C CB  1 
ATOM   9074  O  OG  . SER C 1 278 ? 9.917   51.009  -20.376 1.00 36.17  ? 278 SER C OG  1 
ATOM   9075  N  N   . LEU C 1 279 ? 12.978  53.598  -22.847 1.00 32.35  ? 279 LEU C N   1 
ATOM   9076  C  CA  . LEU C 1 279 ? 13.558  54.028  -24.122 1.00 37.85  ? 279 LEU C CA  1 
ATOM   9077  C  C   . LEU C 1 279 ? 14.877  53.345  -24.467 1.00 37.36  ? 279 LEU C C   1 
ATOM   9078  O  O   . LEU C 1 279 ? 15.045  52.939  -25.633 1.00 40.08  ? 279 LEU C O   1 
ATOM   9079  C  CB  . LEU C 1 279 ? 13.721  55.550  -24.119 1.00 36.72  ? 279 LEU C CB  1 
ATOM   9080  C  CG  . LEU C 1 279 ? 12.434  56.313  -24.409 1.00 38.33  ? 279 LEU C CG  1 
ATOM   9081  C  CD1 . LEU C 1 279 ? 12.686  57.803  -24.378 1.00 42.72  ? 279 LEU C CD1 1 
ATOM   9082  C  CD2 . LEU C 1 279 ? 11.892  55.876  -25.777 1.00 34.67  ? 279 LEU C CD2 1 
ATOM   9083  N  N   . PRO C 1 280 ? 15.853  53.210  -23.549 1.00 39.76  ? 280 PRO C N   1 
ATOM   9084  C  CA  . PRO C 1 280 ? 17.104  52.520  -23.926 1.00 35.65  ? 280 PRO C CA  1 
ATOM   9085  C  C   . PRO C 1 280 ? 16.888  51.111  -24.475 1.00 38.04  ? 280 PRO C C   1 
ATOM   9086  O  O   . PRO C 1 280 ? 17.557  50.718  -25.441 1.00 36.65  ? 280 PRO C O   1 
ATOM   9087  C  CB  . PRO C 1 280 ? 17.898  52.505  -22.611 1.00 34.90  ? 280 PRO C CB  1 
ATOM   9088  C  CG  . PRO C 1 280 ? 17.348  53.620  -21.815 1.00 35.81  ? 280 PRO C CG  1 
ATOM   9089  C  CD  . PRO C 1 280 ? 15.902  53.697  -22.155 1.00 33.92  ? 280 PRO C CD  1 
ATOM   9090  N  N   . LEU C 1 281 ? 15.959  50.339  -23.901 1.00 36.34  ? 281 LEU C N   1 
ATOM   9091  C  CA  . LEU C 1 281 ? 15.691  49.017  -24.451 1.00 32.45  ? 281 LEU C CA  1 
ATOM   9092  C  C   . LEU C 1 281 ? 14.980  49.119  -25.791 1.00 30.14  ? 281 LEU C C   1 
ATOM   9093  O  O   . LEU C 1 281 ? 15.277  48.359  -26.711 1.00 33.96  ? 281 LEU C O   1 
ATOM   9094  C  CB  . LEU C 1 281 ? 14.870  48.173  -23.464 1.00 38.71  ? 281 LEU C CB  1 
ATOM   9095  C  CG  . LEU C 1 281 ? 14.420  46.810  -24.024 1.00 35.73  ? 281 LEU C CG  1 
ATOM   9096  C  CD1 . LEU C 1 281 ? 15.505  45.780  -23.807 1.00 30.21  ? 281 LEU C CD1 1 
ATOM   9097  C  CD2 . LEU C 1 281 ? 13.089  46.302  -23.432 1.00 33.54  ? 281 LEU C CD2 1 
ATOM   9098  N  N   . ALA C 1 282 ? 14.040  50.052  -25.924 1.00 33.92  ? 282 ALA C N   1 
ATOM   9099  C  CA  . ALA C 1 282 ? 13.391  50.266  -27.214 1.00 36.50  ? 282 ALA C CA  1 
ATOM   9100  C  C   . ALA C 1 282 ? 14.408  50.620  -28.284 1.00 34.70  ? 282 ALA C C   1 
ATOM   9101  O  O   . ALA C 1 282 ? 14.344  50.116  -29.411 1.00 40.26  ? 282 ALA C O   1 
ATOM   9102  C  CB  . ALA C 1 282 ? 12.346  51.371  -27.106 1.00 38.71  ? 282 ALA C CB  1 
ATOM   9103  N  N   . GLU C 1 283 ? 15.338  51.511  -27.955 1.00 41.00  ? 283 GLU C N   1 
ATOM   9104  C  CA  . GLU C 1 283 ? 16.417  51.819  -28.884 1.00 42.48  ? 283 GLU C CA  1 
ATOM   9105  C  C   . GLU C 1 283 ? 17.279  50.590  -29.112 1.00 42.88  ? 283 GLU C C   1 
ATOM   9106  O  O   . GLU C 1 283 ? 17.740  50.343  -30.233 1.00 40.18  ? 283 GLU C O   1 
ATOM   9107  C  CB  . GLU C 1 283 ? 17.257  52.984  -28.352 1.00 42.76  ? 283 GLU C CB  1 
ATOM   9108  C  CG  . GLU C 1 283 ? 18.208  53.588  -29.376 1.00 53.89  ? 283 GLU C CG  1 
ATOM   9109  C  CD  . GLU C 1 283 ? 19.525  54.036  -28.772 1.00 56.89  ? 283 GLU C CD  1 
ATOM   9110  O  OE1 . GLU C 1 283 ? 19.591  55.176  -28.256 1.00 58.31  ? 283 GLU C OE1 1 
ATOM   9111  O  OE2 . GLU C 1 283 ? 20.493  53.243  -28.819 1.00 57.08  ? 283 GLU C OE2 1 
ATOM   9112  N  N   . GLU C 1 284 ? 17.468  49.778  -28.064 1.00 40.41  ? 284 GLU C N   1 
ATOM   9113  C  CA  . GLU C 1 284 ? 18.302  48.590  -28.189 1.00 35.05  ? 284 GLU C CA  1 
ATOM   9114  C  C   . GLU C 1 284 ? 17.647  47.515  -29.051 1.00 37.61  ? 284 GLU C C   1 
ATOM   9115  O  O   . GLU C 1 284 ? 18.345  46.756  -29.733 1.00 41.20  ? 284 GLU C O   1 
ATOM   9116  C  CB  . GLU C 1 284 ? 18.629  48.035  -26.804 1.00 39.43  ? 284 GLU C CB  1 
ATOM   9117  C  CG  . GLU C 1 284 ? 19.395  46.721  -26.856 1.00 41.52  ? 284 GLU C CG  1 
ATOM   9118  C  CD  . GLU C 1 284 ? 19.279  45.915  -25.582 1.00 48.02  ? 284 GLU C CD  1 
ATOM   9119  O  OE1 . GLU C 1 284 ? 19.497  46.489  -24.489 1.00 47.24  ? 284 GLU C OE1 1 
ATOM   9120  O  OE2 . GLU C 1 284 ? 18.976  44.703  -25.675 1.00 52.39  ? 284 GLU C OE2 1 
ATOM   9121  N  N   . LEU C 1 285 ? 16.320  47.435  -29.045 1.00 35.63  ? 285 LEU C N   1 
ATOM   9122  C  CA  . LEU C 1 285 ? 15.610  46.442  -29.839 1.00 34.96  ? 285 LEU C CA  1 
ATOM   9123  C  C   . LEU C 1 285 ? 15.191  46.954  -31.209 1.00 33.67  ? 285 LEU C C   1 
ATOM   9124  O  O   . LEU C 1 285 ? 14.773  46.151  -32.052 1.00 30.93  ? 285 LEU C O   1 
ATOM   9125  C  CB  . LEU C 1 285 ? 14.369  45.972  -29.086 1.00 36.76  ? 285 LEU C CB  1 
ATOM   9126  C  CG  . LEU C 1 285 ? 14.694  45.295  -27.755 1.00 33.42  ? 285 LEU C CG  1 
ATOM   9127  C  CD1 . LEU C 1 285 ? 13.426  44.924  -27.003 1.00 34.33  ? 285 LEU C CD1 1 
ATOM   9128  C  CD2 . LEU C 1 285 ? 15.554  44.079  -28.023 1.00 31.10  ? 285 LEU C CD2 1 
ATOM   9129  N  N   . ASP C 1 286 ? 15.305  48.261  -31.449 1.00 38.16  ? 286 ASP C N   1 
ATOM   9130  C  CA  . ASP C 1 286 ? 14.836  48.882  -32.685 1.00 36.34  ? 286 ASP C CA  1 
ATOM   9131  C  C   . ASP C 1 286 ? 13.334  48.679  -32.854 1.00 37.57  ? 286 ASP C C   1 
ATOM   9132  O  O   . ASP C 1 286 ? 12.845  48.317  -33.930 1.00 38.99  ? 286 ASP C O   1 
ATOM   9133  C  CB  . ASP C 1 286 ? 15.592  48.364  -33.903 1.00 38.32  ? 286 ASP C CB  1 
ATOM   9134  C  CG  . ASP C 1 286 ? 15.556  49.349  -35.050 1.00 38.47  ? 286 ASP C CG  1 
ATOM   9135  O  OD1 . ASP C 1 286 ? 15.261  50.534  -34.771 1.00 33.11  ? 286 ASP C OD1 1 
ATOM   9136  O  OD2 . ASP C 1 286 ? 15.814  48.939  -36.203 1.00 38.61  ? 286 ASP C OD2 1 
ATOM   9137  N  N   . VAL C 1 287 ? 12.609  48.877  -31.759 1.00 36.85  ? 287 VAL C N   1 
ATOM   9138  C  CA  . VAL C 1 287 ? 11.154  48.909  -31.730 1.00 35.88  ? 287 VAL C CA  1 
ATOM   9139  C  C   . VAL C 1 287 ? 10.764  50.295  -31.242 1.00 35.16  ? 287 VAL C C   1 
ATOM   9140  O  O   . VAL C 1 287 ? 11.380  50.818  -30.306 1.00 39.35  ? 287 VAL C O   1 
ATOM   9141  C  CB  . VAL C 1 287 ? 10.581  47.804  -30.810 1.00 30.10  ? 287 VAL C CB  1 
ATOM   9142  C  CG1 . VAL C 1 287 ? 9.067   47.840  -30.781 1.00 32.22  ? 287 VAL C CG1 1 
ATOM   9143  C  CG2 . VAL C 1 287 ? 11.031  46.460  -31.307 1.00 36.72  ? 287 VAL C CG2 1 
ATOM   9144  N  N   . ILE C 1 288 ? 9.785   50.912  -31.902 1.00 33.11  ? 288 ILE C N   1 
ATOM   9145  C  CA  . ILE C 1 288 ? 9.380   52.276  -31.585 1.00 34.35  ? 288 ILE C CA  1 
ATOM   9146  C  C   . ILE C 1 288 ? 8.150   52.243  -30.689 1.00 37.41  ? 288 ILE C C   1 
ATOM   9147  O  O   . ILE C 1 288 ? 7.183   51.516  -30.969 1.00 34.40  ? 288 ILE C O   1 
ATOM   9148  C  CB  . ILE C 1 288 ? 9.105   53.096  -32.858 1.00 34.36  ? 288 ILE C CB  1 
ATOM   9149  C  CG1 . ILE C 1 288 ? 10.416  53.537  -33.510 1.00 37.24  ? 288 ILE C CG1 1 
ATOM   9150  C  CG2 . ILE C 1 288 ? 8.248   54.302  -32.551 1.00 36.41  ? 288 ILE C CG2 1 
ATOM   9151  C  CD1 . ILE C 1 288 ? 10.208  54.259  -34.777 1.00 37.91  ? 288 ILE C CD1 1 
ATOM   9152  N  N   . ILE C 1 289 ? 8.182   53.057  -29.635 1.00 31.68  ? 289 ILE C N   1 
ATOM   9153  C  CA  . ILE C 1 289 ? 7.068   53.238  -28.716 1.00 35.19  ? 289 ILE C CA  1 
ATOM   9154  C  C   . ILE C 1 289 ? 6.188   54.368  -29.238 1.00 38.28  ? 289 ILE C C   1 
ATOM   9155  O  O   . ILE C 1 289 ? 6.638   55.514  -29.331 1.00 40.56  ? 289 ILE C O   1 
ATOM   9156  C  CB  . ILE C 1 289 ? 7.578   53.561  -27.303 1.00 30.44  ? 289 ILE C CB  1 
ATOM   9157  C  CG1 . ILE C 1 289 ? 8.578   52.512  -26.823 1.00 28.83  ? 289 ILE C CG1 1 
ATOM   9158  C  CG2 . ILE C 1 289 ? 6.442   53.700  -26.327 1.00 34.54  ? 289 ILE C CG2 1 
ATOM   9159  C  CD1 . ILE C 1 289 ? 9.364   52.961  -25.624 1.00 29.02  ? 289 ILE C CD1 1 
ATOM   9160  N  N   . CYS C 1 290 ? 4.929   54.065  -29.549 1.00 34.03  ? 290 CYS C N   1 
ATOM   9161  C  CA  . CYS C 1 290 ? 3.991   55.061  -30.072 1.00 35.88  ? 290 CYS C CA  1 
ATOM   9162  C  C   . CYS C 1 290 ? 2.642   54.963  -29.370 1.00 35.47  ? 290 CYS C C   1 
ATOM   9163  O  O   . CYS C 1 290 ? 1.807   54.125  -29.750 1.00 32.18  ? 290 CYS C O   1 
ATOM   9164  C  CB  . CYS C 1 290 ? 3.805   54.923  -31.585 1.00 28.82  ? 290 CYS C CB  1 
ATOM   9165  S  SG  . CYS C 1 290 ? 3.463   53.246  -32.260 1.00 38.11  ? 290 CYS C SG  1 
ATOM   9166  N  N   . PRO C 1 291 ? 2.383   55.806  -28.367 1.00 31.01  ? 291 PRO C N   1 
ATOM   9167  C  CA  . PRO C 1 291 ? 1.037   55.877  -27.799 1.00 34.14  ? 291 PRO C CA  1 
ATOM   9168  C  C   . PRO C 1 291 ? 0.031   56.350  -28.823 1.00 32.38  ? 291 PRO C C   1 
ATOM   9169  O  O   . PRO C 1 291 ? 0.361   57.068  -29.774 1.00 35.79  ? 291 PRO C O   1 
ATOM   9170  C  CB  . PRO C 1 291 ? 1.178   56.891  -26.653 1.00 38.07  ? 291 PRO C CB  1 
ATOM   9171  C  CG  . PRO C 1 291 ? 2.465   57.579  -26.886 1.00 40.33  ? 291 PRO C CG  1 
ATOM   9172  C  CD  . PRO C 1 291 ? 3.346   56.597  -27.581 1.00 36.58  ? 291 PRO C CD  1 
ATOM   9173  N  N   . GLU C 1 292 ? -1.218  55.962  -28.593 1.00 31.13  ? 292 GLU C N   1 
ATOM   9174  C  CA  . GLU C 1 292 ? -2.320  56.236  -29.505 1.00 35.01  ? 292 GLU C CA  1 
ATOM   9175  C  C   . GLU C 1 292 ? -3.028  57.543  -29.148 1.00 40.71  ? 292 GLU C C   1 
ATOM   9176  O  O   . GLU C 1 292 ? -3.419  57.750  -27.992 1.00 40.98  ? 292 GLU C O   1 
ATOM   9177  C  CB  . GLU C 1 292 ? -3.305  55.068  -29.461 1.00 35.10  ? 292 GLU C CB  1 
ATOM   9178  C  CG  . GLU C 1 292 ? -4.584  55.293  -30.224 1.00 36.81  ? 292 GLU C CG  1 
ATOM   9179  C  CD  . GLU C 1 292 ? -5.540  54.132  -30.093 1.00 32.90  ? 292 GLU C CD  1 
ATOM   9180  O  OE1 . GLU C 1 292 ? -5.248  53.187  -29.317 1.00 36.09  ? 292 GLU C OE1 1 
ATOM   9181  O  OE2 . GLU C 1 292 ? -6.584  54.160  -30.770 1.00 32.01  ? 292 GLU C OE2 1 
ATOM   9182  N  N   . ILE C 1 293 ? -3.175  58.423  -30.142 1.00 34.35  ? 293 ILE C N   1 
ATOM   9183  C  CA  . ILE C 1 293 ? -4.045  59.595  -30.061 1.00 35.74  ? 293 ILE C CA  1 
ATOM   9184  C  C   . ILE C 1 293 ? -5.419  59.141  -30.546 1.00 33.21  ? 293 ILE C C   1 
ATOM   9185  O  O   . ILE C 1 293 ? -5.657  59.030  -31.756 1.00 37.39  ? 293 ILE C O   1 
ATOM   9186  C  CB  . ILE C 1 293 ? -3.523  60.765  -30.903 1.00 33.21  ? 293 ILE C CB  1 
ATOM   9187  C  CG1 . ILE C 1 293 ? -2.006  60.937  -30.784 1.00 32.91  ? 293 ILE C CG1 1 
ATOM   9188  C  CG2 . ILE C 1 293 ? -4.234  62.036  -30.522 1.00 38.65  ? 293 ILE C CG2 1 
ATOM   9189  C  CD1 . ILE C 1 293 ? -1.484  60.960  -29.352 1.00 41.89  ? 293 ILE C CD1 1 
ATOM   9190  N  N   . HIS C 1 294 ? -6.323  58.884  -29.597 1.00 34.39  ? 294 HIS C N   1 
ATOM   9191  C  CA  . HIS C 1 294 ? -7.663  58.345  -29.820 1.00 35.03  ? 294 HIS C CA  1 
ATOM   9192  C  C   . HIS C 1 294 ? -8.676  59.402  -29.379 1.00 37.33  ? 294 HIS C C   1 
ATOM   9193  O  O   . HIS C 1 294 ? -8.448  60.101  -28.382 1.00 35.51  ? 294 HIS C O   1 
ATOM   9194  C  CB  . HIS C 1 294 ? -7.831  57.020  -29.003 1.00 36.46  ? 294 HIS C CB  1 
ATOM   9195  C  CG  . HIS C 1 294 ? -9.152  56.318  -29.166 1.00 40.41  ? 294 HIS C CG  1 
ATOM   9196  N  ND1 . HIS C 1 294 ? -9.289  54.955  -28.989 1.00 44.82  ? 294 HIS C ND1 1 
ATOM   9197  C  CD2 . HIS C 1 294 ? -10.384 56.770  -29.504 1.00 43.26  ? 294 HIS C CD2 1 
ATOM   9198  C  CE1 . HIS C 1 294 ? -10.549 54.606  -29.189 1.00 41.81  ? 294 HIS C CE1 1 
ATOM   9199  N  NE2 . HIS C 1 294 ? -11.235 55.690  -29.504 1.00 41.62  ? 294 HIS C NE2 1 
ATOM   9200  N  N   . SER C 1 295 ? -9.771  59.549  -30.133 1.00 30.47  ? 295 SER C N   1 
ATOM   9201  C  CA  . SER C 1 295 ? -10.862 60.423  -29.708 1.00 34.31  ? 295 SER C CA  1 
ATOM   9202  C  C   . SER C 1 295 ? -11.298 60.051  -28.290 1.00 39.42  ? 295 SER C C   1 
ATOM   9203  O  O   . SER C 1 295 ? -11.327 58.860  -27.952 1.00 39.69  ? 295 SER C O   1 
ATOM   9204  C  CB  . SER C 1 295 ? -12.049 60.298  -30.670 1.00 31.96  ? 295 SER C CB  1 
ATOM   9205  O  OG  . SER C 1 295 ? -13.159 61.099  -30.273 1.00 34.02  ? 295 SER C OG  1 
ATOM   9206  N  N   . PRO C 1 296 ? -11.665 61.026  -27.432 1.00 38.90  ? 296 PRO C N   1 
ATOM   9207  C  CA  . PRO C 1 296 ? -11.889 62.453  -27.645 1.00 35.03  ? 296 PRO C CA  1 
ATOM   9208  C  C   . PRO C 1 296 ? -10.626 63.294  -27.632 1.00 37.87  ? 296 PRO C C   1 
ATOM   9209  O  O   . PRO C 1 296 ? -10.742 64.518  -27.697 1.00 38.82  ? 296 PRO C O   1 
ATOM   9210  C  CB  . PRO C 1 296 ? -12.774 62.826  -26.460 1.00 39.02  ? 296 PRO C CB  1 
ATOM   9211  C  CG  . PRO C 1 296 ? -12.213 61.998  -25.359 1.00 41.14  ? 296 PRO C CG  1 
ATOM   9212  C  CD  . PRO C 1 296 ? -11.808 60.686  -26.001 1.00 41.45  ? 296 PRO C CD  1 
ATOM   9213  N  N   . THR C 1 297 ? -9.453  62.683  -27.549 1.00 32.02  ? 297 THR C N   1 
ATOM   9214  C  CA  . THR C 1 297 ? -8.237  63.490  -27.600 1.00 36.76  ? 297 THR C CA  1 
ATOM   9215  C  C   . THR C 1 297 ? -8.007  64.051  -28.998 1.00 34.37  ? 297 THR C C   1 
ATOM   9216  O  O   . THR C 1 297 ? -7.825  63.273  -29.942 1.00 36.92  ? 297 THR C O   1 
ATOM   9217  C  CB  . THR C 1 297 ? -7.029  62.683  -27.190 1.00 31.36  ? 297 THR C CB  1 
ATOM   9218  O  OG1 . THR C 1 297 ? -7.344  61.905  -26.035 1.00 35.87  ? 297 THR C OG1 1 
ATOM   9219  C  CG2 . THR C 1 297 ? -5.893  63.613  -26.900 1.00 38.36  ? 297 THR C CG2 1 
ATOM   9220  N  N   . PRO C 1 298 ? -7.985  65.363  -29.179 1.00 40.30  ? 298 PRO C N   1 
ATOM   9221  C  CA  . PRO C 1 298 ? -7.609  65.942  -30.476 1.00 37.41  ? 298 PRO C CA  1 
ATOM   9222  C  C   . PRO C 1 298 ? -6.092  65.920  -30.645 1.00 38.56  ? 298 PRO C C   1 
ATOM   9223  O  O   . PRO C 1 298 ? -5.354  65.478  -29.776 1.00 41.00  ? 298 PRO C O   1 
ATOM   9224  C  CB  . PRO C 1 298 ? -8.131  67.373  -30.371 1.00 34.22  ? 298 PRO C CB  1 
ATOM   9225  C  CG  . PRO C 1 298 ? -7.912  67.699  -28.917 1.00 40.29  ? 298 PRO C CG  1 
ATOM   9226  C  CD  . PRO C 1 298 ? -8.209  66.404  -28.157 1.00 35.86  ? 298 PRO C CD  1 
ATOM   9227  N  N   . ILE C 1 299 ? -5.624  66.423  -31.787 1.00 40.63  ? 299 ILE C N   1 
ATOM   9228  C  CA  . ILE C 1 299 ? -4.179  66.551  -31.948 1.00 40.26  ? 299 ILE C CA  1 
ATOM   9229  C  C   . ILE C 1 299 ? -3.650  67.782  -31.208 1.00 44.24  ? 299 ILE C C   1 
ATOM   9230  O  O   . ILE C 1 299 ? -2.510  67.781  -30.712 1.00 35.74  ? 299 ILE C O   1 
ATOM   9231  C  CB  . ILE C 1 299 ? -3.799  66.595  -33.433 1.00 41.00  ? 299 ILE C CB  1 
ATOM   9232  C  CG1 . ILE C 1 299 ? -4.314  65.356  -34.164 1.00 41.60  ? 299 ILE C CG1 1 
ATOM   9233  C  CG2 . ILE C 1 299 ? -2.290  66.718  -33.594 1.00 40.31  ? 299 ILE C CG2 1 
ATOM   9234  C  CD1 . ILE C 1 299 ? -3.833  65.301  -35.584 1.00 38.88  ? 299 ILE C CD1 1 
ATOM   9235  N  N   . LYS C 1 300 ? -4.448  68.845  -31.128 1.00 39.81  ? 300 LYS C N   1 
ATOM   9236  C  CA  . LYS C 1 300 ? -4.073  70.028  -30.366 1.00 42.61  ? 300 LYS C CA  1 
ATOM   9237  C  C   . LYS C 1 300 ? -4.604  69.835  -28.952 1.00 39.52  ? 300 LYS C C   1 
ATOM   9238  O  O   . LYS C 1 300 ? -5.800  69.986  -28.694 1.00 41.42  ? 300 LYS C O   1 
ATOM   9239  C  CB  . LYS C 1 300 ? -4.605  71.279  -31.049 1.00 44.37  ? 300 LYS C CB  1 
ATOM   9240  C  CG  . LYS C 1 300 ? -3.735  71.694  -32.228 1.00 41.08  ? 300 LYS C CG  1 
ATOM   9241  C  CD  . LYS C 1 300 ? -4.241  72.956  -32.895 1.00 47.09  ? 300 LYS C CD  1 
ATOM   9242  C  CE  . LYS C 1 300 ? -4.229  72.811  -34.409 1.00 53.64  ? 300 LYS C CE  1 
ATOM   9243  N  NZ  . LYS C 1 300 ? -5.258  73.648  -35.104 1.00 49.83  ? 300 LYS C NZ  1 
ATOM   9244  N  N   . HIS C 1 301 ? -3.712  69.463  -28.039 1.00 38.25  ? 301 HIS C N   1 
ATOM   9245  C  CA  . HIS C 1 301 ? -4.100  69.025  -26.702 1.00 43.88  ? 301 HIS C CA  1 
ATOM   9246  C  C   . HIS C 1 301 ? -2.840  68.793  -25.890 1.00 40.30  ? 301 HIS C C   1 
ATOM   9247  O  O   . HIS C 1 301 ? -1.787  68.482  -26.450 1.00 41.99  ? 301 HIS C O   1 
ATOM   9248  C  CB  . HIS C 1 301 ? -4.924  67.740  -26.756 1.00 38.27  ? 301 HIS C CB  1 
ATOM   9249  C  CG  . HIS C 1 301 ? -5.617  67.413  -25.477 1.00 39.44  ? 301 HIS C CG  1 
ATOM   9250  N  ND1 . HIS C 1 301 ? -4.960  66.877  -24.392 1.00 39.39  ? 301 HIS C ND1 1 
ATOM   9251  C  CD2 . HIS C 1 301 ? -6.917  67.524  -25.115 1.00 39.83  ? 301 HIS C CD2 1 
ATOM   9252  C  CE1 . HIS C 1 301 ? -5.820  66.691  -23.409 1.00 39.11  ? 301 HIS C CE1 1 
ATOM   9253  N  NE2 . HIS C 1 301 ? -7.015  67.075  -23.822 1.00 43.87  ? 301 HIS C NE2 1 
ATOM   9254  N  N   . GLU C 1 302 ? -2.963  68.908  -24.564 1.00 43.63  ? 302 GLU C N   1 
ATOM   9255  C  CA  . GLU C 1 302 ? -1.771  68.790  -23.724 1.00 52.42  ? 302 GLU C CA  1 
ATOM   9256  C  C   . GLU C 1 302 ? -1.151  67.393  -23.793 1.00 48.87  ? 302 GLU C C   1 
ATOM   9257  O  O   . GLU C 1 302 ? 0.078   67.266  -23.728 1.00 49.12  ? 302 GLU C O   1 
ATOM   9258  C  CB  . GLU C 1 302 ? -2.066  69.177  -22.259 1.00 50.11  ? 302 GLU C CB  1 
ATOM   9259  C  CG  . GLU C 1 302 ? -3.367  68.652  -21.622 1.00 54.24  ? 302 GLU C CG  1 
ATOM   9260  C  CD  . GLU C 1 302 ? -3.487  69.023  -20.126 1.00 64.57  ? 302 GLU C CD  1 
ATOM   9261  O  OE1 . GLU C 1 302 ? -2.454  68.991  -19.419 1.00 64.16  ? 302 GLU C OE1 1 
ATOM   9262  O  OE2 . GLU C 1 302 ? -4.607  69.337  -19.651 1.00 59.75  ? 302 GLU C OE2 1 
ATOM   9263  N  N   . VAL C 1 303 ? -1.955  66.336  -23.940 1.00 42.29  ? 303 VAL C N   1 
ATOM   9264  C  CA  . VAL C 1 303 ? -1.345  65.006  -23.969 1.00 49.46  ? 303 VAL C CA  1 
ATOM   9265  C  C   . VAL C 1 303 ? -0.488  64.836  -25.222 1.00 44.79  ? 303 VAL C C   1 
ATOM   9266  O  O   . VAL C 1 303 ? 0.605   64.256  -25.167 1.00 40.28  ? 303 VAL C O   1 
ATOM   9267  C  CB  . VAL C 1 303 ? -2.401  63.888  -23.846 1.00 51.19  ? 303 VAL C CB  1 
ATOM   9268  C  CG1 . VAL C 1 303 ? -3.467  64.231  -22.808 1.00 46.50  ? 303 VAL C CG1 1 
ATOM   9269  C  CG2 . VAL C 1 303 ? -3.015  63.553  -25.185 1.00 48.44  ? 303 VAL C CG2 1 
ATOM   9270  N  N   . VAL C 1 304 ? -0.950  65.354  -26.364 1.00 45.23  ? 304 VAL C N   1 
ATOM   9271  C  CA  . VAL C 1 304 ? -0.108  65.318  -27.550 1.00 43.94  ? 304 VAL C CA  1 
ATOM   9272  C  C   . VAL C 1 304 ? 1.098   66.208  -27.339 1.00 41.86  ? 304 VAL C C   1 
ATOM   9273  O  O   . VAL C 1 304 ? 2.230   65.846  -27.686 1.00 42.06  ? 304 VAL C O   1 
ATOM   9274  C  CB  . VAL C 1 304 ? -0.889  65.738  -28.808 1.00 46.42  ? 304 VAL C CB  1 
ATOM   9275  C  CG1 . VAL C 1 304 ? 0.061   65.810  -29.999 1.00 33.42  ? 304 VAL C CG1 1 
ATOM   9276  C  CG2 . VAL C 1 304 ? -2.039  64.776  -29.096 1.00 39.47  ? 304 VAL C CG2 1 
ATOM   9277  N  N   . ASP C 1 305 ? 0.869   67.382  -26.752 1.00 43.35  ? 305 ASP C N   1 
ATOM   9278  C  CA  . ASP C 1 305 ? 1.950   68.319  -26.495 1.00 45.17  ? 305 ASP C CA  1 
ATOM   9279  C  C   . ASP C 1 305 ? 3.063   67.663  -25.693 1.00 45.99  ? 305 ASP C C   1 
ATOM   9280  O  O   . ASP C 1 305 ? 4.250   67.855  -25.985 1.00 41.62  ? 305 ASP C O   1 
ATOM   9281  C  CB  . ASP C 1 305 ? 1.400   69.545  -25.761 1.00 48.89  ? 305 ASP C CB  1 
ATOM   9282  C  CG  . ASP C 1 305 ? 0.830   70.590  -26.711 1.00 51.70  ? 305 ASP C CG  1 
ATOM   9283  O  OD1 . ASP C 1 305 ? 1.466   70.852  -27.756 1.00 48.01  ? 305 ASP C OD1 1 
ATOM   9284  O  OD2 . ASP C 1 305 ? -0.246  71.153  -26.405 1.00 52.61  ? 305 ASP C OD2 1 
ATOM   9285  N  N   . ASP C 1 306 ? 2.694   66.850  -24.698 1.00 46.35  ? 306 ASP C N   1 
ATOM   9286  C  CA  . ASP C 1 306 ? 3.683   66.277  -23.794 1.00 40.96  ? 306 ASP C CA  1 
ATOM   9287  C  C   . ASP C 1 306 ? 4.458   65.133  -24.433 1.00 41.06  ? 306 ASP C C   1 
ATOM   9288  O  O   . ASP C 1 306 ? 5.646   64.966  -24.146 1.00 44.16  ? 306 ASP C O   1 
ATOM   9289  C  CB  . ASP C 1 306 ? 2.990   65.831  -22.508 1.00 46.60  ? 306 ASP C CB  1 
ATOM   9290  C  CG  . ASP C 1 306 ? 2.630   67.010  -21.615 1.00 54.72  ? 306 ASP C CG  1 
ATOM   9291  O  OD1 . ASP C 1 306 ? 2.908   68.161  -22.033 1.00 48.78  ? 306 ASP C OD1 1 
ATOM   9292  O  OD2 . ASP C 1 306 ? 2.060   66.791  -20.518 1.00 44.37  ? 306 ASP C OD2 1 
ATOM   9293  N  N   . TYR C 1 307 ? 3.818   64.340  -25.293 1.00 44.87  ? 307 TYR C N   1 
ATOM   9294  C  CA  . TYR C 1 307 ? 4.556   63.376  -26.103 1.00 39.51  ? 307 TYR C CA  1 
ATOM   9295  C  C   . TYR C 1 307 ? 5.682   64.056  -26.875 1.00 37.81  ? 307 TYR C C   1 
ATOM   9296  O  O   . TYR C 1 307 ? 6.824   63.590  -26.863 1.00 40.96  ? 307 TYR C O   1 
ATOM   9297  C  CB  . TYR C 1 307 ? 3.606   62.670  -27.064 1.00 40.66  ? 307 TYR C CB  1 
ATOM   9298  C  CG  . TYR C 1 307 ? 2.602   61.782  -26.389 1.00 44.88  ? 307 TYR C CG  1 
ATOM   9299  C  CD1 . TYR C 1 307 ? 2.931   61.068  -25.245 1.00 48.60  ? 307 TYR C CD1 1 
ATOM   9300  C  CD2 . TYR C 1 307 ? 1.311   61.671  -26.881 1.00 45.30  ? 307 TYR C CD2 1 
ATOM   9301  C  CE1 . TYR C 1 307 ? 2.003   60.256  -24.619 1.00 47.62  ? 307 TYR C CE1 1 
ATOM   9302  C  CE2 . TYR C 1 307 ? 0.378   60.860  -26.262 1.00 44.76  ? 307 TYR C CE2 1 
ATOM   9303  C  CZ  . TYR C 1 307 ? 0.727   60.156  -25.134 1.00 46.63  ? 307 TYR C CZ  1 
ATOM   9304  O  OH  . TYR C 1 307 ? -0.214  59.345  -24.524 1.00 49.91  ? 307 TYR C OH  1 
ATOM   9305  N  N   . ILE C 1 308 ? 5.377   65.169  -27.548 1.00 40.90  ? 308 ILE C N   1 
ATOM   9306  C  CA  . ILE C 1 308 ? 6.396   65.884  -28.320 1.00 38.97  ? 308 ILE C CA  1 
ATOM   9307  C  C   . ILE C 1 308 ? 7.465   66.456  -27.403 1.00 39.28  ? 308 ILE C C   1 
ATOM   9308  O  O   . ILE C 1 308 ? 8.661   66.420  -27.720 1.00 42.61  ? 308 ILE C O   1 
ATOM   9309  C  CB  . ILE C 1 308 ? 5.753   66.994  -29.174 1.00 40.79  ? 308 ILE C CB  1 
ATOM   9310  C  CG1 . ILE C 1 308 ? 4.486   66.491  -29.861 1.00 43.12  ? 308 ILE C CG1 1 
ATOM   9311  C  CG2 . ILE C 1 308 ? 6.757   67.540  -30.189 1.00 46.76  ? 308 ILE C CG2 1 
ATOM   9312  C  CD1 . ILE C 1 308 ? 4.761   65.468  -30.931 1.00 46.14  ? 308 ILE C CD1 1 
ATOM   9313  N  N   . ALA C 1 309 ? 7.054   67.009  -26.260 1.00 38.25  ? 309 ALA C N   1 
ATOM   9314  C  CA  . ALA C 1 309 ? 8.028   67.493  -25.291 1.00 39.31  ? 309 ALA C CA  1 
ATOM   9315  C  C   . ALA C 1 309 ? 8.989   66.381  -24.898 1.00 47.66  ? 309 ALA C C   1 
ATOM   9316  O  O   . ALA C 1 309 ? 10.195  66.616  -24.725 1.00 44.62  ? 309 ALA C O   1 
ATOM   9317  C  CB  . ALA C 1 309 ? 7.305   68.051  -24.068 1.00 41.79  ? 309 ALA C CB  1 
ATOM   9318  N  N   . LEU C 1 310 ? 8.467   65.156  -24.775 1.00 43.85  ? 310 LEU C N   1 
ATOM   9319  C  CA  . LEU C 1 310 ? 9.308   64.006  -24.470 1.00 47.84  ? 310 LEU C CA  1 
ATOM   9320  C  C   . LEU C 1 310 ? 10.300  63.751  -25.590 1.00 41.35  ? 310 LEU C C   1 
ATOM   9321  O  O   . LEU C 1 310 ? 11.500  63.573  -25.343 1.00 40.84  ? 310 LEU C O   1 
ATOM   9322  C  CB  . LEU C 1 310 ? 8.444   62.763  -24.237 1.00 42.70  ? 310 LEU C CB  1 
ATOM   9323  C  CG  . LEU C 1 310 ? 9.223   61.453  -24.059 1.00 43.33  ? 310 LEU C CG  1 
ATOM   9324  C  CD1 . LEU C 1 310 ? 9.990   61.453  -22.750 1.00 46.71  ? 310 LEU C CD1 1 
ATOM   9325  C  CD2 . LEU C 1 310 ? 8.276   60.257  -24.137 1.00 50.93  ? 310 LEU C CD2 1 
ATOM   9326  N  N   . ILE C 1 311 ? 9.809   63.717  -26.832 1.00 42.59  ? 311 ILE C N   1 
ATOM   9327  C  CA  . ILE C 1 311 ? 10.689  63.488  -27.972 1.00 44.03  ? 311 ILE C CA  1 
ATOM   9328  C  C   . ILE C 1 311 ? 11.768  64.559  -28.021 1.00 48.00  ? 311 ILE C C   1 
ATOM   9329  O  O   . ILE C 1 311 ? 12.931  64.276  -28.337 1.00 44.91  ? 311 ILE C O   1 
ATOM   9330  C  CB  . ILE C 1 311 ? 9.877   63.435  -29.280 1.00 43.11  ? 311 ILE C CB  1 
ATOM   9331  C  CG1 . ILE C 1 311 ? 8.850   62.295  -29.231 1.00 44.65  ? 311 ILE C CG1 1 
ATOM   9332  C  CG2 . ILE C 1 311 ? 10.801  63.238  -30.451 1.00 38.57  ? 311 ILE C CG2 1 
ATOM   9333  C  CD1 . ILE C 1 311 ? 7.721   62.399  -30.258 1.00 40.71  ? 311 ILE C CD1 1 
ATOM   9334  N  N   . ARG C 1 312 ? 11.406  65.798  -27.673 1.00 48.14  ? 312 ARG C N   1 
ATOM   9335  C  CA  . ARG C 1 312 ? 12.353  66.906  -27.727 1.00 45.43  ? 312 ARG C CA  1 
ATOM   9336  C  C   . ARG C 1 312 ? 13.463  66.733  -26.702 1.00 44.70  ? 312 ARG C C   1 
ATOM   9337  O  O   . ARG C 1 312 ? 14.649  66.770  -27.044 1.00 49.08  ? 312 ARG C O   1 
ATOM   9338  C  CB  . ARG C 1 312 ? 11.619  68.231  -27.516 1.00 48.24  ? 312 ARG C CB  1 
ATOM   9339  C  CG  . ARG C 1 312 ? 10.866  68.676  -28.753 1.00 47.96  ? 312 ARG C CG  1 
ATOM   9340  C  CD  . ARG C 1 312 ? 9.988   69.866  -28.497 1.00 50.07  ? 312 ARG C CD  1 
ATOM   9341  N  NE  . ARG C 1 312 ? 9.389   70.290  -29.752 1.00 53.08  ? 312 ARG C NE  1 
ATOM   9342  C  CZ  . ARG C 1 312 ? 8.814   71.465  -29.955 1.00 56.05  ? 312 ARG C CZ  1 
ATOM   9343  N  NH1 . ARG C 1 312 ? 8.724   72.370  -28.991 1.00 62.75  ? 312 ARG C NH1 1 
ATOM   9344  N  NH2 . ARG C 1 312 ? 8.312   71.739  -31.156 1.00 58.16  ? 312 ARG C NH2 1 
ATOM   9345  N  N   . ARG C 1 313 ? 13.101  66.544  -25.435 1.00 50.53  ? 313 ARG C N   1 
ATOM   9346  C  CA  . ARG C 1 313 ? 14.121  66.438  -24.394 1.00 50.70  ? 313 ARG C CA  1 
ATOM   9347  C  C   . ARG C 1 313 ? 15.008  65.205  -24.605 1.00 47.19  ? 313 ARG C C   1 
ATOM   9348  O  O   . ARG C 1 313 ? 16.242  65.303  -24.602 1.00 44.10  ? 313 ARG C O   1 
ATOM   9349  C  CB  . ARG C 1 313 ? 13.439  66.442  -23.021 1.00 48.94  ? 313 ARG C CB  1 
ATOM   9350  C  CG  . ARG C 1 313 ? 14.103  65.615  -21.931 1.00 51.64  ? 313 ARG C CG  1 
ATOM   9351  C  CD  . ARG C 1 313 ? 13.235  65.609  -20.671 1.00 56.51  ? 313 ARG C CD  1 
ATOM   9352  N  NE  . ARG C 1 313 ? 12.110  64.681  -20.766 1.00 50.23  ? 313 ARG C NE  1 
ATOM   9353  C  CZ  . ARG C 1 313 ? 10.846  65.047  -20.946 1.00 47.68  ? 313 ARG C CZ  1 
ATOM   9354  N  NH1 . ARG C 1 313 ? 10.501  66.319  -21.041 1.00 47.84  ? 313 ARG C NH1 1 
ATOM   9355  N  NH2 . ARG C 1 313 ? 9.905   64.113  -21.029 1.00 46.31  ? 313 ARG C NH2 1 
ATOM   9356  N  N   . THR C 1 314 ? 14.402  64.039  -24.843 1.00 50.31  ? 314 THR C N   1 
ATOM   9357  C  CA  . THR C 1 314 ? 15.200  62.818  -24.971 1.00 50.64  ? 314 THR C CA  1 
ATOM   9358  C  C   . THR C 1 314 ? 16.053  62.802  -26.232 1.00 48.78  ? 314 THR C C   1 
ATOM   9359  O  O   . THR C 1 314 ? 17.153  62.239  -26.223 1.00 49.72  ? 314 THR C O   1 
ATOM   9360  C  CB  . THR C 1 314 ? 14.306  61.587  -24.987 1.00 50.11  ? 314 THR C CB  1 
ATOM   9361  O  OG1 . THR C 1 314 ? 13.606  61.542  -26.241 1.00 47.43  ? 314 THR C OG1 1 
ATOM   9362  C  CG2 . THR C 1 314 ? 13.329  61.606  -23.818 1.00 43.15  ? 314 THR C CG2 1 
ATOM   9363  N  N   . GLY C 1 315 ? 15.562  63.372  -27.327 1.00 44.81  ? 315 GLY C N   1 
ATOM   9364  C  CA  . GLY C 1 315 ? 16.254  63.184  -28.580 1.00 44.99  ? 315 GLY C CA  1 
ATOM   9365  C  C   . GLY C 1 315 ? 16.155  61.781  -29.131 1.00 53.21  ? 315 GLY C C   1 
ATOM   9366  O  O   . GLY C 1 315 ? 16.994  61.391  -29.949 1.00 51.06  ? 315 GLY C O   1 
ATOM   9367  N  N   . THR C 1 316 ? 15.152  61.004  -28.707 1.00 46.15  ? 316 THR C N   1 
ATOM   9368  C  CA  . THR C 1 316 ? 15.012  59.627  -29.169 1.00 46.96  ? 316 THR C CA  1 
ATOM   9369  C  C   . THR C 1 316 ? 14.455  59.577  -30.590 1.00 41.74  ? 316 THR C C   1 
ATOM   9370  O  O   . THR C 1 316 ? 13.668  60.432  -31.007 1.00 44.57  ? 316 THR C O   1 
ATOM   9371  C  CB  . THR C 1 316 ? 14.101  58.818  -28.224 1.00 45.19  ? 316 THR C CB  1 
ATOM   9372  O  OG1 . THR C 1 316 ? 14.093  57.440  -28.615 1.00 40.90  ? 316 THR C OG1 1 
ATOM   9373  C  CG2 . THR C 1 316 ? 12.672  59.328  -28.273 1.00 42.10  ? 316 THR C CG2 1 
ATOM   9374  N  N   . LYS C 1 317 ? 14.882  58.560  -31.335 1.00 41.83  ? 317 LYS C N   1 
ATOM   9375  C  CA  . LYS C 1 317 ? 14.256  58.171  -32.594 1.00 46.28  ? 317 LYS C CA  1 
ATOM   9376  C  C   . LYS C 1 317 ? 13.239  57.053  -32.414 1.00 41.52  ? 317 LYS C C   1 
ATOM   9377  O  O   . LYS C 1 317 ? 12.675  56.576  -33.403 1.00 38.04  ? 317 LYS C O   1 
ATOM   9378  C  CB  . LYS C 1 317 ? 15.321  57.725  -33.604 1.00 44.40  ? 317 LYS C CB  1 
ATOM   9379  C  CG  . LYS C 1 317 ? 16.538  58.636  -33.687 1.00 49.72  ? 317 LYS C CG  1 
ATOM   9380  C  CD  . LYS C 1 317 ? 17.831  57.832  -33.616 1.00 51.32  ? 317 LYS C CD  1 
ATOM   9381  C  CE  . LYS C 1 317 ? 17.927  57.100  -32.265 1.00 55.17  ? 317 LYS C CE  1 
ATOM   9382  N  NZ  . LYS C 1 317 ? 19.266  56.530  -31.928 1.00 48.17  ? 317 LYS C NZ  1 
ATOM   9383  N  N   . HIS C 1 318 ? 12.994  56.624  -31.176 1.00 46.64  ? 318 HIS C N   1 
ATOM   9384  C  CA  . HIS C 1 318 ? 12.186  55.444  -30.889 1.00 42.89  ? 318 HIS C CA  1 
ATOM   9385  C  C   . HIS C 1 318 ? 10.987  55.766  -30.004 1.00 42.10  ? 318 HIS C C   1 
ATOM   9386  O  O   . HIS C 1 318 ? 10.533  54.928  -29.224 1.00 39.67  ? 318 HIS C O   1 
ATOM   9387  C  CB  . HIS C 1 318 ? 13.052  54.361  -30.260 1.00 37.91  ? 318 HIS C CB  1 
ATOM   9388  C  CG  . HIS C 1 318 ? 14.138  53.887  -31.160 1.00 37.64  ? 318 HIS C CG  1 
ATOM   9389  N  ND1 . HIS C 1 318 ? 15.424  54.369  -31.088 1.00 41.81  ? 318 HIS C ND1 1 
ATOM   9390  C  CD2 . HIS C 1 318 ? 14.121  53.001  -32.183 1.00 38.61  ? 318 HIS C CD2 1 
ATOM   9391  C  CE1 . HIS C 1 318 ? 16.161  53.783  -32.014 1.00 40.77  ? 318 HIS C CE1 1 
ATOM   9392  N  NE2 . HIS C 1 318 ? 15.395  52.948  -32.692 1.00 44.53  ? 318 HIS C NE2 1 
ATOM   9393  N  N   . PHE C 1 319 ? 10.471  56.983  -30.111 1.00 39.70  ? 319 PHE C N   1 
ATOM   9394  C  CA  . PHE C 1 319 ? 9.200   57.336  -29.505 1.00 37.03  ? 319 PHE C CA  1 
ATOM   9395  C  C   . PHE C 1 319 ? 8.470   58.225  -30.494 1.00 40.31  ? 319 PHE C C   1 
ATOM   9396  O  O   . PHE C 1 319 ? 9.051   59.186  -30.998 1.00 37.84  ? 319 PHE C O   1 
ATOM   9397  C  CB  . PHE C 1 319 ? 9.381   58.052  -28.161 1.00 37.18  ? 319 PHE C CB  1 
ATOM   9398  C  CG  . PHE C 1 319 ? 8.085   58.354  -27.463 1.00 34.75  ? 319 PHE C CG  1 
ATOM   9399  C  CD1 . PHE C 1 319 ? 7.534   57.447  -26.564 1.00 37.41  ? 319 PHE C CD1 1 
ATOM   9400  C  CD2 . PHE C 1 319 ? 7.398   59.525  -27.729 1.00 37.34  ? 319 PHE C CD2 1 
ATOM   9401  C  CE1 . PHE C 1 319 ? 6.343   57.715  -25.934 1.00 37.04  ? 319 PHE C CE1 1 
ATOM   9402  C  CE2 . PHE C 1 319 ? 6.195   59.798  -27.109 1.00 39.95  ? 319 PHE C CE2 1 
ATOM   9403  C  CZ  . PHE C 1 319 ? 5.667   58.894  -26.204 1.00 41.91  ? 319 PHE C CZ  1 
ATOM   9404  N  N   . GLY C 1 320 ? 7.209   57.907  -30.775 1.00 35.31  ? 320 GLY C N   1 
ATOM   9405  C  CA  . GLY C 1 320 ? 6.478   58.660  -31.779 1.00 32.17  ? 320 GLY C CA  1 
ATOM   9406  C  C   . GLY C 1 320 ? 4.987   58.656  -31.527 1.00 36.01  ? 320 GLY C C   1 
ATOM   9407  O  O   . GLY C 1 320 ? 4.530   58.169  -30.492 1.00 34.51  ? 320 GLY C O   1 
ATOM   9408  N  N   . LEU C 1 321 ? 4.211   59.189  -32.456 1.00 31.95  ? 321 LEU C N   1 
ATOM   9409  C  CA  . LEU C 1 321 ? 2.767   59.229  -32.312 1.00 34.03  ? 321 LEU C CA  1 
ATOM   9410  C  C   . LEU C 1 321 ? 2.114   58.183  -33.194 1.00 34.55  ? 321 LEU C C   1 
ATOM   9411  O  O   . LEU C 1 321 ? 2.459   58.050  -34.371 1.00 34.55  ? 321 LEU C O   1 
ATOM   9412  C  CB  . LEU C 1 321 ? 2.232   60.610  -32.683 1.00 40.63  ? 321 LEU C CB  1 
ATOM   9413  C  CG  . LEU C 1 321 ? 2.976   61.743  -31.983 1.00 36.17  ? 321 LEU C CG  1 
ATOM   9414  C  CD1 . LEU C 1 321 ? 2.599   63.067  -32.616 1.00 38.07  ? 321 LEU C CD1 1 
ATOM   9415  C  CD2 . LEU C 1 321 ? 2.646   61.723  -30.515 1.00 38.72  ? 321 LEU C CD2 1 
ATOM   9416  N  N   . LEU C 1 322 ? 1.163   57.444  -32.629 1.00 33.87  ? 322 LEU C N   1 
ATOM   9417  C  CA  . LEU C 1 322 ? 0.243   56.635  -33.419 1.00 34.46  ? 322 LEU C CA  1 
ATOM   9418  C  C   . LEU C 1 322 ? -1.073  57.391  -33.519 1.00 36.54  ? 322 LEU C C   1 
ATOM   9419  O  O   . LEU C 1 322 ? -1.618  57.834  -32.505 1.00 37.19  ? 322 LEU C O   1 
ATOM   9420  C  CB  . LEU C 1 322 ? 0.056   55.235  -32.811 1.00 30.85  ? 322 LEU C CB  1 
ATOM   9421  C  CG  . LEU C 1 322 ? -0.832  54.182  -33.485 1.00 35.39  ? 322 LEU C CG  1 
ATOM   9422  C  CD1 . LEU C 1 322 ? -0.646  52.840  -32.804 1.00 38.91  ? 322 LEU C CD1 1 
ATOM   9423  C  CD2 . LEU C 1 322 ? -2.329  54.533  -33.425 1.00 30.72  ? 322 LEU C CD2 1 
ATOM   9424  N  N   . LEU C 1 323 ? -1.561  57.578  -34.738 1.00 36.34  ? 323 LEU C N   1 
ATOM   9425  C  CA  . LEU C 1 323 ? -2.807  58.303  -34.940 1.00 35.16  ? 323 LEU C CA  1 
ATOM   9426  C  C   . LEU C 1 323 ? -3.927  57.316  -35.185 1.00 29.10  ? 323 LEU C C   1 
ATOM   9427  O  O   . LEU C 1 323 ? -3.776  56.374  -35.963 1.00 34.89  ? 323 LEU C O   1 
ATOM   9428  C  CB  . LEU C 1 323 ? -2.721  59.280  -36.118 1.00 32.79  ? 323 LEU C CB  1 
ATOM   9429  C  CG  . LEU C 1 323 ? -2.393  60.730  -35.810 1.00 39.40  ? 323 LEU C CG  1 
ATOM   9430  C  CD1 . LEU C 1 323 ? -1.307  60.819  -34.752 1.00 43.64  ? 323 LEU C CD1 1 
ATOM   9431  C  CD2 . LEU C 1 323 ? -2.003  61.457  -37.091 1.00 42.36  ? 323 LEU C CD2 1 
ATOM   9432  N  N   . ASP C 1 324 ? -5.053  57.546  -34.530 1.00 34.79  ? 324 ASP C N   1 
ATOM   9433  C  CA  . ASP C 1 324 ? -6.270  56.779  -34.740 1.00 31.09  ? 324 ASP C CA  1 
ATOM   9434  C  C   . ASP C 1 324 ? -7.237  57.665  -35.499 1.00 32.58  ? 324 ASP C C   1 
ATOM   9435  O  O   . ASP C 1 324 ? -7.613  58.734  -35.007 1.00 36.21  ? 324 ASP C O   1 
ATOM   9436  C  CB  . ASP C 1 324 ? -6.873  56.335  -33.405 1.00 35.30  ? 324 ASP C CB  1 
ATOM   9437  C  CG  . ASP C 1 324 ? -8.114  55.472  -33.571 1.00 30.23  ? 324 ASP C CG  1 
ATOM   9438  O  OD1 . ASP C 1 324 ? -9.140  55.970  -34.079 1.00 32.18  ? 324 ASP C OD1 1 
ATOM   9439  O  OD2 . ASP C 1 324 ? -8.068  54.290  -33.166 1.00 35.67  ? 324 ASP C OD2 1 
ATOM   9440  N  N   . THR C 1 325 ? -7.658  57.216  -36.680 1.00 35.31  ? 325 THR C N   1 
ATOM   9441  C  CA  . THR C 1 325 ? -8.418  58.121  -37.542 1.00 38.00  ? 325 THR C CA  1 
ATOM   9442  C  C   . THR C 1 325 ? -9.822  58.408  -37.024 1.00 34.81  ? 325 THR C C   1 
ATOM   9443  O  O   . THR C 1 325 ? -10.540 59.170  -37.678 1.00 37.45  ? 325 THR C O   1 
ATOM   9444  C  CB  . THR C 1 325 ? -8.511  57.590  -38.988 1.00 33.76  ? 325 THR C CB  1 
ATOM   9445  O  OG1 . THR C 1 325 ? -9.233  56.356  -39.022 1.00 31.06  ? 325 THR C OG1 1 
ATOM   9446  C  CG2 . THR C 1 325 ? -7.129  57.435  -39.631 1.00 30.61  ? 325 THR C CG2 1 
ATOM   9447  N  N   . GLY C 1 326 ? -10.236 57.832  -35.891 1.00 36.40  ? 326 GLY C N   1 
ATOM   9448  C  CA  . GLY C 1 326 ? -11.462 58.274  -35.239 1.00 30.42  ? 326 GLY C CA  1 
ATOM   9449  C  C   . GLY C 1 326 ? -11.451 59.738  -34.826 1.00 27.38  ? 326 GLY C C   1 
ATOM   9450  O  O   . GLY C 1 326 ? -12.517 60.353  -34.724 1.00 30.26  ? 326 GLY C O   1 
ATOM   9451  N  N   . ILE C 1 327 ? -10.267 60.320  -34.612 1.00 32.50  ? 327 ILE C N   1 
ATOM   9452  C  CA  . ILE C 1 327 ? -10.197 61.740  -34.280 1.00 32.62  ? 327 ILE C CA  1 
ATOM   9453  C  C   . ILE C 1 327 ? -10.800 62.569  -35.404 1.00 33.99  ? 327 ILE C C   1 
ATOM   9454  O  O   . ILE C 1 327 ? -11.383 63.630  -35.162 1.00 35.02  ? 327 ILE C O   1 
ATOM   9455  C  CB  . ILE C 1 327 ? -8.743  62.171  -33.967 1.00 28.60  ? 327 ILE C CB  1 
ATOM   9456  C  CG1 . ILE C 1 327 ? -7.821  61.949  -35.166 1.00 29.49  ? 327 ILE C CG1 1 
ATOM   9457  C  CG2 . ILE C 1 327 ? -8.200  61.433  -32.755 1.00 29.78  ? 327 ILE C CG2 1 
ATOM   9458  C  CD1 . ILE C 1 327 ? -6.371  62.314  -34.890 1.00 34.64  ? 327 ILE C CD1 1 
ATOM   9459  N  N   . PHE C 1 328 ? -10.718 62.084  -36.639 1.00 34.36  ? 328 PHE C N   1 
ATOM   9460  C  CA  . PHE C 1 328 ? -11.212 62.842  -37.782 1.00 34.13  ? 328 PHE C CA  1 
ATOM   9461  C  C   . PHE C 1 328 ? -12.698 62.660  -38.029 1.00 34.33  ? 328 PHE C C   1 
ATOM   9462  O  O   . PHE C 1 328 ? -13.225 63.290  -38.952 1.00 39.28  ? 328 PHE C O   1 
ATOM   9463  C  CB  . PHE C 1 328 ? -10.449 62.454  -39.045 1.00 34.51  ? 328 PHE C CB  1 
ATOM   9464  C  CG  . PHE C 1 328 ? -8.954  62.606  -38.921 1.00 36.80  ? 328 PHE C CG  1 
ATOM   9465  C  CD1 . PHE C 1 328 ? -8.389  63.838  -38.650 1.00 36.07  ? 328 PHE C CD1 1 
ATOM   9466  C  CD2 . PHE C 1 328 ? -8.116  61.513  -39.075 1.00 32.55  ? 328 PHE C CD2 1 
ATOM   9467  C  CE1 . PHE C 1 328 ? -7.025  63.980  -38.538 1.00 37.28  ? 328 PHE C CE1 1 
ATOM   9468  C  CE2 . PHE C 1 328 ? -6.739  61.657  -38.966 1.00 38.20  ? 328 PHE C CE2 1 
ATOM   9469  C  CZ  . PHE C 1 328 ? -6.194  62.892  -38.703 1.00 28.44  ? 328 PHE C CZ  1 
ATOM   9470  N  N   . GLN C 1 329 ? -13.382 61.825  -37.244 1.00 30.63  ? 329 GLN C N   1 
ATOM   9471  C  CA  . GLN C 1 329 ? -14.778 61.504  -37.522 1.00 29.63  ? 329 GLN C CA  1 
ATOM   9472  C  C   . GLN C 1 329 ? -15.631 62.771  -37.563 1.00 37.17  ? 329 GLN C C   1 
ATOM   9473  O  O   . GLN C 1 329 ? -15.510 63.643  -36.695 1.00 33.67  ? 329 GLN C O   1 
ATOM   9474  C  CB  . GLN C 1 329 ? -15.291 60.532  -36.458 1.00 37.61  ? 329 GLN C CB  1 
ATOM   9475  C  CG  . GLN C 1 329 ? -16.804 60.310  -36.419 1.00 37.55  ? 329 GLN C CG  1 
ATOM   9476  C  CD  . GLN C 1 329 ? -17.221 59.500  -35.193 1.00 39.08  ? 329 GLN C CD  1 
ATOM   9477  O  OE1 . GLN C 1 329 ? -16.374 59.142  -34.367 1.00 35.27  ? 329 GLN C OE1 1 
ATOM   9478  N  NE2 . GLN C 1 329 ? -18.524 59.232  -35.054 1.00 33.79  ? 329 GLN C NE2 1 
ATOM   9479  N  N   . ASP C 1 330 ? -16.490 62.877  -38.585 1.00 37.15  ? 330 ASP C N   1 
ATOM   9480  C  CA  . ASP C 1 330 ? -17.281 64.085  -38.824 1.00 39.36  ? 330 ASP C CA  1 
ATOM   9481  C  C   . ASP C 1 330 ? -18.775 63.805  -38.903 1.00 39.68  ? 330 ASP C C   1 
ATOM   9482  O  O   . ASP C 1 330 ? -19.538 64.673  -39.340 1.00 40.53  ? 330 ASP C O   1 
ATOM   9483  C  CB  . ASP C 1 330 ? -16.806 64.812  -40.101 1.00 39.32  ? 330 ASP C CB  1 
ATOM   9484  C  CG  . ASP C 1 330 ? -17.153 64.055  -41.402 1.00 40.85  ? 330 ASP C CG  1 
ATOM   9485  O  OD1 . ASP C 1 330 ? -17.210 62.805  -41.399 1.00 43.53  ? 330 ASP C OD1 1 
ATOM   9486  O  OD2 . ASP C 1 330 ? -17.334 64.707  -42.450 1.00 37.90  ? 330 ASP C OD2 1 
ATOM   9487  N  N   . ARG C 1 331 ? -19.214 62.621  -38.497 1.00 37.60  ? 331 ARG C N   1 
ATOM   9488  C  CA  . ARG C 1 331 ? -20.622 62.254  -38.506 1.00 40.63  ? 331 ARG C CA  1 
ATOM   9489  C  C   . ARG C 1 331 ? -20.824 61.269  -37.369 1.00 39.91  ? 331 ARG C C   1 
ATOM   9490  O  O   . ARG C 1 331 ? -19.904 60.514  -37.043 1.00 37.37  ? 331 ARG C O   1 
ATOM   9491  C  CB  . ARG C 1 331 ? -21.048 61.622  -39.841 1.00 41.18  ? 331 ARG C CB  1 
ATOM   9492  C  CG  . ARG C 1 331 ? -21.515 62.612  -40.893 1.00 43.28  ? 331 ARG C CG  1 
ATOM   9493  C  CD  . ARG C 1 331 ? -21.142 62.160  -42.316 1.00 43.04  ? 331 ARG C CD  1 
ATOM   9494  N  NE  . ARG C 1 331 ? -19.721 61.878  -42.491 1.00 38.41  ? 331 ARG C NE  1 
ATOM   9495  C  CZ  . ARG C 1 331 ? -19.252 60.858  -43.195 1.00 37.11  ? 331 ARG C CZ  1 
ATOM   9496  N  NH1 . ARG C 1 331 ? -20.065 60.017  -43.808 1.00 41.72  ? 331 ARG C NH1 1 
ATOM   9497  N  NH2 . ARG C 1 331 ? -17.940 60.669  -43.275 1.00 32.39  ? 331 ARG C NH2 1 
ATOM   9498  N  N   . PRO C 1 332 ? -21.994 61.252  -36.748 1.00 42.14  ? 332 PRO C N   1 
ATOM   9499  C  CA  . PRO C 1 332 ? -22.144 60.491  -35.504 1.00 42.22  ? 332 PRO C CA  1 
ATOM   9500  C  C   . PRO C 1 332 ? -22.291 58.997  -35.743 1.00 47.21  ? 332 PRO C C   1 
ATOM   9501  O  O   . PRO C 1 332 ? -22.907 58.558  -36.718 1.00 48.05  ? 332 PRO C O   1 
ATOM   9502  C  CB  . PRO C 1 332 ? -23.419 61.072  -34.877 1.00 46.82  ? 332 PRO C CB  1 
ATOM   9503  C  CG  . PRO C 1 332 ? -24.151 61.760  -35.969 1.00 47.34  ? 332 PRO C CG  1 
ATOM   9504  C  CD  . PRO C 1 332 ? -23.232 61.940  -37.154 1.00 45.05  ? 332 PRO C CD  1 
ATOM   9505  N  N   . ILE C 1 333 ? -21.705 58.216  -34.835 1.00 43.88  ? 333 ILE C N   1 
ATOM   9506  C  CA  . ILE C 1 333 ? -22.022 56.785  -34.788 1.00 42.99  ? 333 ILE C CA  1 
ATOM   9507  C  C   . ILE C 1 333 ? -23.519 56.632  -34.564 1.00 45.76  ? 333 ILE C C   1 
ATOM   9508  O  O   . ILE C 1 333 ? -24.105 57.400  -33.777 1.00 46.95  ? 333 ILE C O   1 
ATOM   9509  C  CB  . ILE C 1 333 ? -21.225 56.088  -33.669 1.00 42.37  ? 333 ILE C CB  1 
ATOM   9510  C  CG1 . ILE C 1 333 ? -19.734 56.091  -33.973 1.00 39.26  ? 333 ILE C CG1 1 
ATOM   9511  C  CG2 . ILE C 1 333 ? -21.686 54.653  -33.463 1.00 43.77  ? 333 ILE C CG2 1 
ATOM   9512  C  CD1 . ILE C 1 333 ? -18.943 55.343  -32.915 1.00 45.76  ? 333 ILE C CD1 1 
ATOM   9513  N  N   . PRO C 1 334 ? -24.196 55.693  -35.218 1.00 49.84  ? 334 PRO C N   1 
ATOM   9514  C  CA  . PRO C 1 334 ? -25.634 55.542  -34.990 1.00 51.72  ? 334 PRO C CA  1 
ATOM   9515  C  C   . PRO C 1 334 ? -25.937 55.272  -33.528 1.00 53.73  ? 334 PRO C C   1 
ATOM   9516  O  O   . PRO C 1 334 ? -25.094 54.799  -32.763 1.00 52.42  ? 334 PRO C O   1 
ATOM   9517  C  CB  . PRO C 1 334 ? -26.010 54.341  -35.865 1.00 52.06  ? 334 PRO C CB  1 
ATOM   9518  C  CG  . PRO C 1 334 ? -24.969 54.341  -36.942 1.00 51.17  ? 334 PRO C CG  1 
ATOM   9519  C  CD  . PRO C 1 334 ? -23.707 54.773  -36.258 1.00 49.56  ? 334 PRO C CD  1 
ATOM   9520  N  N   . LEU C 1 335 ? -27.168 55.594  -33.148 1.00 63.11  ? 335 LEU C N   1 
ATOM   9521  C  CA  . LEU C 1 335 ? -27.678 55.306  -31.818 1.00 66.86  ? 335 LEU C CA  1 
ATOM   9522  C  C   . LEU C 1 335 ? -28.277 53.907  -31.802 1.00 68.82  ? 335 LEU C C   1 
ATOM   9523  O  O   . LEU C 1 335 ? -28.856 53.452  -32.793 1.00 67.71  ? 335 LEU C O   1 
ATOM   9524  C  CB  . LEU C 1 335 ? -28.745 56.327  -31.422 1.00 69.26  ? 335 LEU C CB  1 
ATOM   9525  C  CG  . LEU C 1 335 ? -28.256 57.660  -30.856 1.00 66.47  ? 335 LEU C CG  1 
ATOM   9526  C  CD1 . LEU C 1 335 ? -29.362 58.720  -30.933 1.00 60.28  ? 335 LEU C CD1 1 
ATOM   9527  C  CD2 . LEU C 1 335 ? -27.721 57.496  -29.447 1.00 70.54  ? 335 LEU C CD2 1 
ATOM   9528  N  N   . LYS C 1 336 ? -28.122 53.217  -30.670 1.00 73.38  ? 336 LYS C N   1 
ATOM   9529  C  CA  . LYS C 1 336 ? -28.830 51.955  -30.507 1.00 76.33  ? 336 LYS C CA  1 
ATOM   9530  C  C   . LYS C 1 336 ? -30.311 52.235  -30.226 1.00 76.42  ? 336 LYS C C   1 
ATOM   9531  O  O   . LYS C 1 336 ? -30.651 53.278  -29.659 1.00 75.66  ? 336 LYS C O   1 
ATOM   9532  C  CB  . LYS C 1 336 ? -28.212 51.145  -29.366 1.00 71.52  ? 336 LYS C CB  1 
ATOM   9533  C  CG  . LYS C 1 336 ? -28.421 49.629  -29.451 1.00 75.83  ? 336 LYS C CG  1 
ATOM   9534  C  CD  . LYS C 1 336 ? -29.314 49.119  -28.316 1.00 78.87  ? 336 LYS C CD  1 
ATOM   9535  C  CE  . LYS C 1 336 ? -29.507 47.605  -28.372 1.00 75.33  ? 336 LYS C CE  1 
ATOM   9536  N  NZ  . LYS C 1 336 ? -28.212 46.872  -28.433 1.00 63.81  ? 336 LYS C NZ  1 
ATOM   9537  N  N   . PRO C 1 337 ? -31.220 51.353  -30.652 1.00 81.14  ? 337 PRO C N   1 
ATOM   9538  C  CA  . PRO C 1 337 ? -32.630 51.533  -30.272 1.00 79.50  ? 337 PRO C CA  1 
ATOM   9539  C  C   . PRO C 1 337 ? -32.799 51.409  -28.766 1.00 78.58  ? 337 PRO C C   1 
ATOM   9540  O  O   . PRO C 1 337 ? -32.131 50.607  -28.109 1.00 80.68  ? 337 PRO C O   1 
ATOM   9541  C  CB  . PRO C 1 337 ? -33.365 50.416  -31.026 1.00 78.26  ? 337 PRO C CB  1 
ATOM   9542  C  CG  . PRO C 1 337 ? -32.323 49.488  -31.538 1.00 80.72  ? 337 PRO C CG  1 
ATOM   9543  C  CD  . PRO C 1 337 ? -31.022 50.226  -31.583 1.00 81.11  ? 337 PRO C CD  1 
ATOM   9544  N  N   . GLY C 1 338 ? -33.696 52.221  -28.217 1.00 75.99  ? 338 GLY C N   1 
ATOM   9545  C  CA  . GLY C 1 338 ? -33.795 52.360  -26.782 1.00 78.25  ? 338 GLY C CA  1 
ATOM   9546  C  C   . GLY C 1 338 ? -32.849 53.379  -26.192 1.00 79.65  ? 338 GLY C C   1 
ATOM   9547  O  O   . GLY C 1 338 ? -32.868 53.584  -24.972 1.00 80.98  ? 338 GLY C O   1 
ATOM   9548  N  N   . GLU C 1 339 ? -32.017 54.013  -27.017 1.00 80.97  ? 339 GLU C N   1 
ATOM   9549  C  CA  . GLU C 1 339 ? -31.156 55.110  -26.602 1.00 79.95  ? 339 GLU C CA  1 
ATOM   9550  C  C   . GLU C 1 339 ? -31.681 56.408  -27.201 1.00 74.79  ? 339 GLU C C   1 
ATOM   9551  O  O   . GLU C 1 339 ? -32.203 56.419  -28.318 1.00 72.72  ? 339 GLU C O   1 
ATOM   9552  C  CB  . GLU C 1 339 ? -29.704 54.883  -27.041 1.00 79.41  ? 339 GLU C CB  1 
ATOM   9553  C  CG  . GLU C 1 339 ? -28.658 55.349  -26.029 1.00 82.69  ? 339 GLU C CG  1 
ATOM   9554  C  CD  . GLU C 1 339 ? -27.354 55.780  -26.687 1.00 86.21  ? 339 GLU C CD  1 
ATOM   9555  O  OE1 . GLU C 1 339 ? -26.889 56.907  -26.398 1.00 75.10  ? 339 GLU C OE1 1 
ATOM   9556  O  OE2 . GLU C 1 339 ? -26.806 55.007  -27.507 1.00 86.39  ? 339 GLU C OE2 1 
ATOM   9557  N  N   . LEU C 1 340 ? -31.550 57.495  -26.444 1.00 72.50  ? 340 LEU C N   1 
ATOM   9558  C  CA  . LEU C 1 340 ? -32.002 58.816  -26.859 1.00 73.02  ? 340 LEU C CA  1 
ATOM   9559  C  C   . LEU C 1 340 ? -30.816 59.772  -26.775 1.00 76.35  ? 340 LEU C C   1 
ATOM   9560  O  O   . LEU C 1 340 ? -29.756 59.385  -26.266 1.00 77.58  ? 340 LEU C O   1 
ATOM   9561  C  CB  . LEU C 1 340 ? -33.153 59.300  -25.971 1.00 77.33  ? 340 LEU C CB  1 
ATOM   9562  C  CG  . LEU C 1 340 ? -34.433 58.463  -25.856 1.00 77.77  ? 340 LEU C CG  1 
ATOM   9563  C  CD1 . LEU C 1 340 ? -35.436 59.188  -24.963 1.00 71.81  ? 340 LEU C CD1 1 
ATOM   9564  C  CD2 . LEU C 1 340 ? -35.046 58.119  -27.216 1.00 77.48  ? 340 LEU C CD2 1 
ATOM   9565  N  N   . PRO C 1 341 ? -30.933 61.003  -27.278 1.00 76.16  ? 341 PRO C N   1 
ATOM   9566  C  CA  . PRO C 1 341 ? -29.843 61.973  -27.106 1.00 73.22  ? 341 PRO C CA  1 
ATOM   9567  C  C   . PRO C 1 341 ? -29.432 62.128  -25.646 1.00 77.39  ? 341 PRO C C   1 
ATOM   9568  O  O   . PRO C 1 341 ? -30.255 62.033  -24.732 1.00 80.76  ? 341 PRO C O   1 
ATOM   9569  C  CB  . PRO C 1 341 ? -30.445 63.272  -27.652 1.00 74.93  ? 341 PRO C CB  1 
ATOM   9570  C  CG  . PRO C 1 341 ? -31.389 62.810  -28.707 1.00 78.15  ? 341 PRO C CG  1 
ATOM   9571  C  CD  . PRO C 1 341 ? -31.948 61.485  -28.235 1.00 75.86  ? 341 PRO C CD  1 
ATOM   9572  N  N   . GLY C 1 342 ? -28.132 62.354  -25.432 1.00 72.04  ? 342 GLY C N   1 
ATOM   9573  C  CA  . GLY C 1 342 ? -27.605 62.689  -24.126 1.00 62.73  ? 342 GLY C CA  1 
ATOM   9574  C  C   . GLY C 1 342 ? -27.083 61.531  -23.291 1.00 60.13  ? 342 GLY C C   1 
ATOM   9575  O  O   . GLY C 1 342 ? -26.305 61.773  -22.359 1.00 57.66  ? 342 GLY C O   1 
ATOM   9576  N  N   . GLN C 1 343 ? -27.484 60.286  -23.576 1.00 59.17  ? 343 GLN C N   1 
ATOM   9577  C  CA  . GLN C 1 343 ? -27.090 59.146  -22.750 1.00 60.50  ? 343 GLN C CA  1 
ATOM   9578  C  C   . GLN C 1 343 ? -25.741 58.544  -23.130 1.00 55.08  ? 343 GLN C C   1 
ATOM   9579  O  O   . GLN C 1 343 ? -25.426 57.434  -22.689 1.00 56.37  ? 343 GLN C O   1 
ATOM   9580  C  CB  . GLN C 1 343 ? -28.141 58.033  -22.790 1.00 59.18  ? 343 GLN C CB  1 
ATOM   9581  C  CG  . GLN C 1 343 ? -29.558 58.435  -22.480 1.00 63.83  ? 343 GLN C CG  1 
ATOM   9582  C  CD  . GLN C 1 343 ? -30.551 57.418  -23.010 1.00 72.59  ? 343 GLN C CD  1 
ATOM   9583  O  OE1 . GLN C 1 343 ? -31.343 57.711  -23.903 1.00 75.42  ? 343 GLN C OE1 1 
ATOM   9584  N  NE2 . GLN C 1 343 ? -30.491 56.200  -22.477 1.00 69.56  ? 343 GLN C NE2 1 
ATOM   9585  N  N   . ARG C 1 344 ? -24.933 59.240  -23.917 1.00 50.72  ? 344 ARG C N   1 
ATOM   9586  C  CA  . ARG C 1 344 ? -23.660 58.689  -24.349 1.00 49.68  ? 344 ARG C CA  1 
ATOM   9587  C  C   . ARG C 1 344 ? -22.666 59.830  -24.474 1.00 43.89  ? 344 ARG C C   1 
ATOM   9588  O  O   . ARG C 1 344 ? -23.066 60.992  -24.604 1.00 42.45  ? 344 ARG C O   1 
ATOM   9589  C  CB  . ARG C 1 344 ? -23.808 57.935  -25.680 1.00 53.23  ? 344 ARG C CB  1 
ATOM   9590  C  CG  . ARG C 1 344 ? -23.665 58.803  -26.924 1.00 48.38  ? 344 ARG C CG  1 
ATOM   9591  C  CD  . ARG C 1 344 ? -23.727 57.967  -28.184 1.00 50.45  ? 344 ARG C CD  1 
ATOM   9592  N  NE  . ARG C 1 344 ? -23.512 58.794  -29.362 1.00 49.58  ? 344 ARG C NE  1 
ATOM   9593  C  CZ  . ARG C 1 344 ? -23.730 58.410  -30.612 1.00 45.79  ? 344 ARG C CZ  1 
ATOM   9594  N  NH1 . ARG C 1 344 ? -24.233 57.220  -30.895 1.00 46.80  ? 344 ARG C NH1 1 
ATOM   9595  N  NH2 . ARG C 1 344 ? -23.440 59.247  -31.603 1.00 48.87  ? 344 ARG C NH2 1 
ATOM   9596  N  N   . PRO C 1 345 ? -21.368 59.536  -24.432 1.00 41.46  ? 345 PRO C N   1 
ATOM   9597  C  CA  . PRO C 1 345 ? -20.364 60.601  -24.531 1.00 38.73  ? 345 PRO C CA  1 
ATOM   9598  C  C   . PRO C 1 345 ? -20.489 61.422  -25.805 1.00 43.45  ? 345 PRO C C   1 
ATOM   9599  O  O   . PRO C 1 345 ? -20.995 60.961  -26.832 1.00 44.77  ? 345 PRO C O   1 
ATOM   9600  C  CB  . PRO C 1 345 ? -19.043 59.833  -24.498 1.00 42.06  ? 345 PRO C CB  1 
ATOM   9601  C  CG  . PRO C 1 345 ? -19.346 58.626  -23.674 1.00 40.43  ? 345 PRO C CG  1 
ATOM   9602  C  CD  . PRO C 1 345 ? -20.764 58.248  -24.044 1.00 42.70  ? 345 PRO C CD  1 
ATOM   9603  N  N   . ALA C 1 346 ? -20.000 62.661  -25.723 1.00 41.55  ? 346 ALA C N   1 
ATOM   9604  C  CA  . ALA C 1 346 ? -20.131 63.595  -26.834 1.00 47.18  ? 346 ALA C CA  1 
ATOM   9605  C  C   . ALA C 1 346 ? -19.222 63.226  -28.000 1.00 42.69  ? 346 ALA C C   1 
ATOM   9606  O  O   . ALA C 1 346 ? -19.569 63.477  -29.158 1.00 39.96  ? 346 ALA C O   1 
ATOM   9607  C  CB  . ALA C 1 346 ? -19.829 65.015  -26.353 1.00 45.04  ? 346 ALA C CB  1 
ATOM   9608  N  N   . PHE C 1 347 ? -18.060 62.635  -27.721 1.00 43.89  ? 347 PHE C N   1 
ATOM   9609  C  CA  . PHE C 1 347 ? -17.127 62.307  -28.790 1.00 43.62  ? 347 PHE C CA  1 
ATOM   9610  C  C   . PHE C 1 347 ? -17.649 61.198  -29.700 1.00 42.25  ? 347 PHE C C   1 
ATOM   9611  O  O   . PHE C 1 347 ? -17.183 61.082  -30.834 1.00 39.29  ? 347 PHE C O   1 
ATOM   9612  C  CB  . PHE C 1 347 ? -15.753 61.936  -28.202 1.00 43.45  ? 347 PHE C CB  1 
ATOM   9613  C  CG  . PHE C 1 347 ? -15.685 60.557  -27.599 1.00 44.66  ? 347 PHE C CG  1 
ATOM   9614  C  CD1 . PHE C 1 347 ? -15.351 59.457  -28.378 1.00 45.80  ? 347 PHE C CD1 1 
ATOM   9615  C  CD2 . PHE C 1 347 ? -15.934 60.363  -26.252 1.00 44.38  ? 347 PHE C CD2 1 
ATOM   9616  C  CE1 . PHE C 1 347 ? -15.290 58.186  -27.834 1.00 44.99  ? 347 PHE C CE1 1 
ATOM   9617  C  CE2 . PHE C 1 347 ? -15.861 59.095  -25.700 1.00 44.39  ? 347 PHE C CE2 1 
ATOM   9618  C  CZ  . PHE C 1 347 ? -15.539 58.006  -26.500 1.00 48.84  ? 347 PHE C CZ  1 
ATOM   9619  N  N   . LEU C 1 348 ? -18.601 60.382  -29.238 1.00 44.52  ? 348 LEU C N   1 
ATOM   9620  C  CA  . LEU C 1 348 ? -19.167 59.370  -30.119 1.00 43.32  ? 348 LEU C CA  1 
ATOM   9621  C  C   . LEU C 1 348 ? -19.887 59.999  -31.294 1.00 44.00  ? 348 LEU C C   1 
ATOM   9622  O  O   . LEU C 1 348 ? -20.145 59.313  -32.285 1.00 41.06  ? 348 LEU C O   1 
ATOM   9623  C  CB  . LEU C 1 348 ? -20.124 58.454  -29.360 1.00 43.72  ? 348 LEU C CB  1 
ATOM   9624  C  CG  . LEU C 1 348 ? -19.493 57.413  -28.435 1.00 41.53  ? 348 LEU C CG  1 
ATOM   9625  C  CD1 . LEU C 1 348 ? -20.549 56.454  -27.902 1.00 45.86  ? 348 LEU C CD1 1 
ATOM   9626  C  CD2 . LEU C 1 348 ? -18.410 56.643  -29.167 1.00 40.69  ? 348 LEU C CD2 1 
ATOM   9627  N  N   . ASP C 1 349 ? -20.229 61.283  -31.210 1.00 42.73  ? 349 ASP C N   1 
ATOM   9628  C  CA  . ASP C 1 349 ? -20.805 61.944  -32.375 1.00 42.26  ? 349 ASP C CA  1 
ATOM   9629  C  C   . ASP C 1 349 ? -19.737 62.443  -33.344 1.00 37.97  ? 349 ASP C C   1 
ATOM   9630  O  O   . ASP C 1 349 ? -20.073 62.886  -34.446 1.00 41.29  ? 349 ASP C O   1 
ATOM   9631  C  CB  . ASP C 1 349 ? -21.728 63.080  -31.919 1.00 41.97  ? 349 ASP C CB  1 
ATOM   9632  C  CG  . ASP C 1 349 ? -23.014 62.560  -31.267 1.00 46.53  ? 349 ASP C CG  1 
ATOM   9633  O  OD1 . ASP C 1 349 ? -23.632 61.608  -31.802 1.00 50.72  ? 349 ASP C OD1 1 
ATOM   9634  O  OD2 . ASP C 1 349 ? -23.410 63.094  -30.214 1.00 48.42  ? 349 ASP C OD2 1 
ATOM   9635  N  N   . GLY C 1 350 ? -18.464 62.342  -32.977 1.00 37.84  ? 350 GLY C N   1 
ATOM   9636  C  CA  . GLY C 1 350 ? -17.371 62.712  -33.851 1.00 42.02  ? 350 GLY C CA  1 
ATOM   9637  C  C   . GLY C 1 350 ? -16.771 64.033  -33.432 1.00 41.22  ? 350 GLY C C   1 
ATOM   9638  O  O   . GLY C 1 350 ? -17.499 65.017  -33.310 1.00 46.90  ? 350 GLY C O   1 
ATOM   9639  N  N   . ILE C 1 351 ? -15.459 64.087  -33.201 1.00 41.42  ? 351 ILE C N   1 
ATOM   9640  C  CA  . ILE C 1 351 ? -14.841 65.309  -32.698 1.00 36.22  ? 351 ILE C CA  1 
ATOM   9641  C  C   . ILE C 1 351 ? -14.243 66.181  -33.802 1.00 41.97  ? 351 ILE C C   1 
ATOM   9642  O  O   . ILE C 1 351 ? -13.671 67.244  -33.496 1.00 43.13  ? 351 ILE C O   1 
ATOM   9643  C  CB  . ILE C 1 351 ? -13.785 64.979  -31.626 1.00 37.08  ? 351 ILE C CB  1 
ATOM   9644  C  CG1 . ILE C 1 351 ? -12.662 64.120  -32.213 1.00 36.64  ? 351 ILE C CG1 1 
ATOM   9645  C  CG2 . ILE C 1 351 ? -14.456 64.310  -30.455 1.00 38.11  ? 351 ILE C CG2 1 
ATOM   9646  C  CD1 . ILE C 1 351 ? -11.456 63.980  -31.308 1.00 31.61  ? 351 ILE C CD1 1 
ATOM   9647  N  N   . HIS C 1 352 ? -14.346 65.762  -35.072 1.00 38.40  ? 352 HIS C N   1 
ATOM   9648  C  CA  . HIS C 1 352 ? -14.071 66.615  -36.233 1.00 34.93  ? 352 HIS C CA  1 
ATOM   9649  C  C   . HIS C 1 352 ? -12.685 67.235  -36.189 1.00 37.49  ? 352 HIS C C   1 
ATOM   9650  O  O   . HIS C 1 352 ? -12.530 68.431  -36.435 1.00 41.91  ? 352 HIS C O   1 
ATOM   9651  C  CB  . HIS C 1 352 ? -15.100 67.738  -36.372 1.00 41.97  ? 352 HIS C CB  1 
ATOM   9652  C  CG  . HIS C 1 352 ? -16.502 67.273  -36.603 1.00 47.40  ? 352 HIS C CG  1 
ATOM   9653  N  ND1 . HIS C 1 352 ? -17.204 67.577  -37.750 1.00 45.80  ? 352 HIS C ND1 1 
ATOM   9654  C  CD2 . HIS C 1 352 ? -17.349 66.564  -35.818 1.00 46.77  ? 352 HIS C CD2 1 
ATOM   9655  C  CE1 . HIS C 1 352 ? -18.420 67.060  -37.669 1.00 48.82  ? 352 HIS C CE1 1 
ATOM   9656  N  NE2 . HIS C 1 352 ? -18.532 66.436  -36.508 1.00 49.29  ? 352 HIS C NE2 1 
ATOM   9657  N  N   . VAL C 1 353 ? -11.662 66.447  -35.867 1.00 33.69  ? 353 VAL C N   1 
ATOM   9658  C  CA  . VAL C 1 353 ? -10.318 66.994  -35.989 1.00 35.92  ? 353 VAL C CA  1 
ATOM   9659  C  C   . VAL C 1 353 ? -10.094 67.410  -37.438 1.00 42.15  ? 353 VAL C C   1 
ATOM   9660  O  O   . VAL C 1 353 ? -10.566 66.753  -38.377 1.00 39.71  ? 353 VAL C O   1 
ATOM   9661  C  CB  . VAL C 1 353 ? -9.254  65.994  -35.510 1.00 37.04  ? 353 VAL C CB  1 
ATOM   9662  C  CG1 . VAL C 1 353 ? -7.860  66.555  -35.736 1.00 35.50  ? 353 VAL C CG1 1 
ATOM   9663  C  CG2 . VAL C 1 353 ? -9.452  65.701  -34.035 1.00 36.55  ? 353 VAL C CG2 1 
ATOM   9664  N  N   . ASP C 1 354 ? -9.431  68.550  -37.613 1.00 42.45  ? 354 ASP C N   1 
ATOM   9665  C  CA  . ASP C 1 354 ? -9.093  69.076  -38.935 1.00 39.87  ? 354 ASP C CA  1 
ATOM   9666  C  C   . ASP C 1 354 ? -7.913  68.300  -39.505 1.00 39.41  ? 354 ASP C C   1 
ATOM   9667  O  O   . ASP C 1 354 ? -6.813  68.355  -38.933 1.00 36.00  ? 354 ASP C O   1 
ATOM   9668  C  CB  . ASP C 1 354 ? -8.745  70.571  -38.819 1.00 42.32  ? 354 ASP C CB  1 
ATOM   9669  C  CG  . ASP C 1 354 ? -8.463  71.253  -40.171 1.00 46.09  ? 354 ASP C CG  1 
ATOM   9670  O  OD1 . ASP C 1 354 ? -7.843  70.649  -41.069 1.00 44.85  ? 354 ASP C OD1 1 
ATOM   9671  O  OD2 . ASP C 1 354 ? -8.818  72.440  -40.313 1.00 43.45  ? 354 ASP C OD2 1 
ATOM   9672  N  N   . PRO C 1 355 ? -8.081  67.599  -40.633 1.00 34.37  ? 355 PRO C N   1 
ATOM   9673  C  CA  . PRO C 1 355 ? -6.955  66.897  -41.257 1.00 31.50  ? 355 PRO C CA  1 
ATOM   9674  C  C   . PRO C 1 355 ? -5.673  67.703  -41.323 1.00 37.44  ? 355 PRO C C   1 
ATOM   9675  O  O   . PRO C 1 355 ? -4.594  67.142  -41.132 1.00 37.15  ? 355 PRO C O   1 
ATOM   9676  C  CB  . PRO C 1 355 ? -7.486  66.603  -42.661 1.00 39.17  ? 355 PRO C CB  1 
ATOM   9677  C  CG  . PRO C 1 355 ? -8.953  66.413  -42.442 1.00 41.86  ? 355 PRO C CG  1 
ATOM   9678  C  CD  . PRO C 1 355 ? -9.337  67.398  -41.380 1.00 33.25  ? 355 PRO C CD  1 
ATOM   9679  N  N   . ASN C 1 356 ? -5.765  69.011  -41.599 1.00 37.79  ? 356 ASN C N   1 
ATOM   9680  C  CA  . ASN C 1 356 ? -4.556  69.815  -41.749 1.00 41.85  ? 356 ASN C CA  1 
ATOM   9681  C  C   . ASN C 1 356 ? -3.758  69.893  -40.463 1.00 38.70  ? 356 ASN C C   1 
ATOM   9682  O  O   . ASN C 1 356 ? -2.572  70.231  -40.508 1.00 41.60  ? 356 ASN C O   1 
ATOM   9683  C  CB  . ASN C 1 356 ? -4.890  71.229  -42.233 1.00 41.78  ? 356 ASN C CB  1 
ATOM   9684  C  CG  . ASN C 1 356 ? -5.366  71.252  -43.674 1.00 46.80  ? 356 ASN C CG  1 
ATOM   9685  O  OD1 . ASN C 1 356 ? -6.485  71.674  -43.964 1.00 51.69  ? 356 ASN C OD1 1 
ATOM   9686  N  ND2 . ASN C 1 356 ? -4.522  70.771  -44.585 1.00 41.96  ? 356 ASN C ND2 1 
ATOM   9687  N  N   . ASP C 1 357 ? -4.375  69.567  -39.322 1.00 40.07  ? 357 ASP C N   1 
ATOM   9688  C  CA  . ASP C 1 357 ? -3.658  69.606  -38.051 1.00 40.91  ? 357 ASP C CA  1 
ATOM   9689  C  C   . ASP C 1 357 ? -2.469  68.654  -38.035 1.00 36.79  ? 357 ASP C C   1 
ATOM   9690  O  O   . ASP C 1 357 ? -1.504  68.886  -37.299 1.00 39.96  ? 357 ASP C O   1 
ATOM   9691  C  CB  . ASP C 1 357 ? -4.619  69.283  -36.908 1.00 43.65  ? 357 ASP C CB  1 
ATOM   9692  C  CG  . ASP C 1 357 ? -5.551  70.434  -36.604 1.00 42.03  ? 357 ASP C CG  1 
ATOM   9693  O  OD1 . ASP C 1 357 ? -5.322  71.524  -37.152 1.00 47.88  ? 357 ASP C OD1 1 
ATOM   9694  O  OD2 . ASP C 1 357 ? -6.513  70.255  -35.834 1.00 44.56  ? 357 ASP C OD2 1 
ATOM   9695  N  N   . VAL C 1 358 ? -2.513  67.591  -38.846 1.00 42.52  ? 358 VAL C N   1 
ATOM   9696  C  CA  . VAL C 1 358 ? -1.422  66.626  -38.897 1.00 33.78  ? 358 VAL C CA  1 
ATOM   9697  C  C   . VAL C 1 358 ? -0.129  67.259  -39.387 1.00 37.86  ? 358 VAL C C   1 
ATOM   9698  O  O   . VAL C 1 358 ? 0.953   66.719  -39.142 1.00 37.28  ? 358 VAL C O   1 
ATOM   9699  C  CB  . VAL C 1 358 ? -1.819  65.414  -39.776 1.00 41.19  ? 358 VAL C CB  1 
ATOM   9700  C  CG1 . VAL C 1 358 ? -3.235  64.939  -39.450 1.00 36.28  ? 358 VAL C CG1 1 
ATOM   9701  C  CG2 . VAL C 1 358 ? -1.708  65.753  -41.257 1.00 38.92  ? 358 VAL C CG2 1 
ATOM   9702  N  N   . PHE C 1 359 ? -0.208  68.415  -40.053 1.00 44.84  ? 359 PHE C N   1 
ATOM   9703  C  CA  . PHE C 1 359 ? 0.988   69.007  -40.650 1.00 35.39  ? 359 PHE C CA  1 
ATOM   9704  C  C   . PHE C 1 359 ? 2.012   69.396  -39.592 1.00 40.39  ? 359 PHE C C   1 
ATOM   9705  O  O   . PHE C 1 359 ? 3.206   69.118  -39.749 1.00 39.20  ? 359 PHE C O   1 
ATOM   9706  C  CB  . PHE C 1 359 ? 0.599   70.216  -41.496 1.00 38.80  ? 359 PHE C CB  1 
ATOM   9707  C  CG  . PHE C 1 359 ? 0.054   69.855  -42.845 1.00 43.49  ? 359 PHE C CG  1 
ATOM   9708  C  CD1 . PHE C 1 359 ? -1.295  69.612  -43.018 1.00 41.24  ? 359 PHE C CD1 1 
ATOM   9709  C  CD2 . PHE C 1 359 ? 0.892   69.755  -43.944 1.00 44.71  ? 359 PHE C CD2 1 
ATOM   9710  C  CE1 . PHE C 1 359 ? -1.805  69.272  -44.244 1.00 41.04  ? 359 PHE C CE1 1 
ATOM   9711  C  CE2 . PHE C 1 359 ? 0.383   69.417  -45.179 1.00 43.01  ? 359 PHE C CE2 1 
ATOM   9712  C  CZ  . PHE C 1 359 ? -0.969  69.178  -45.328 1.00 42.20  ? 359 PHE C CZ  1 
ATOM   9713  N  N   . ASP C 1 360 ? 1.559   70.021  -38.495 1.00 39.59  ? 360 ASP C N   1 
ATOM   9714  C  CA  . ASP C 1 360 ? 2.455   70.477  -37.433 1.00 42.19  ? 360 ASP C CA  1 
ATOM   9715  C  C   . ASP C 1 360 ? 3.085   69.339  -36.635 1.00 46.33  ? 360 ASP C C   1 
ATOM   9716  O  O   . ASP C 1 360 ? 4.123   69.554  -35.996 1.00 39.93  ? 360 ASP C O   1 
ATOM   9717  C  CB  . ASP C 1 360 ? 1.699   71.388  -36.458 1.00 50.10  ? 360 ASP C CB  1 
ATOM   9718  C  CG  . ASP C 1 360 ? 0.789   72.374  -37.165 1.00 60.46  ? 360 ASP C CG  1 
ATOM   9719  O  OD1 . ASP C 1 360 ? 1.321   73.342  -37.762 1.00 67.60  ? 360 ASP C OD1 1 
ATOM   9720  O  OD2 . ASP C 1 360 ? -0.452  72.187  -37.122 1.00 54.88  ? 360 ASP C OD2 1 
ATOM   9721  N  N   . VAL C 1 361 ? 2.471   68.156  -36.623 1.00 44.17  ? 361 VAL C N   1 
ATOM   9722  C  CA  . VAL C 1 361 ? 2.948   67.020  -35.844 1.00 44.22  ? 361 VAL C CA  1 
ATOM   9723  C  C   . VAL C 1 361 ? 3.412   65.877  -36.732 1.00 46.88  ? 361 VAL C C   1 
ATOM   9724  O  O   . VAL C 1 361 ? 3.644   64.772  -36.232 1.00 51.83  ? 361 VAL C O   1 
ATOM   9725  C  CB  . VAL C 1 361 ? 1.864   66.510  -34.874 1.00 43.28  ? 361 VAL C CB  1 
ATOM   9726  C  CG1 . VAL C 1 361 ? 1.362   67.614  -34.000 1.00 38.61  ? 361 VAL C CG1 1 
ATOM   9727  C  CG2 . VAL C 1 361 ? 0.714   65.890  -35.650 1.00 39.85  ? 361 VAL C CG2 1 
ATOM   9728  N  N   . ILE C 1 362 ? 3.514   66.086  -38.046 1.00 45.69  ? 362 ILE C N   1 
ATOM   9729  C  CA  . ILE C 1 362 ? 3.673   64.918  -38.906 1.00 44.13  ? 362 ILE C CA  1 
ATOM   9730  C  C   . ILE C 1 362 ? 5.084   64.357  -38.813 1.00 42.50  ? 362 ILE C C   1 
ATOM   9731  O  O   . ILE C 1 362 ? 5.301   63.162  -39.042 1.00 42.53  ? 362 ILE C O   1 
ATOM   9732  C  CB  . ILE C 1 362 ? 3.292   65.247  -40.355 1.00 47.15  ? 362 ILE C CB  1 
ATOM   9733  C  CG1 . ILE C 1 362 ? 3.171   63.948  -41.151 1.00 45.58  ? 362 ILE C CG1 1 
ATOM   9734  C  CG2 . ILE C 1 362 ? 4.312   66.175  -40.971 1.00 45.29  ? 362 ILE C CG2 1 
ATOM   9735  C  CD1 . ILE C 1 362 ? 1.759   63.424  -41.227 1.00 44.02  ? 362 ILE C CD1 1 
ATOM   9736  N  N   . GLU C 1 363 ? 6.059   65.183  -38.446 1.00 44.54  ? 363 GLU C N   1 
ATOM   9737  C  CA  . GLU C 1 363 ? 7.418   64.679  -38.308 1.00 49.42  ? 363 GLU C CA  1 
ATOM   9738  C  C   . GLU C 1 363 ? 7.540   63.633  -37.207 1.00 51.84  ? 363 GLU C C   1 
ATOM   9739  O  O   . GLU C 1 363 ? 8.606   63.021  -37.072 1.00 49.05  ? 363 GLU C O   1 
ATOM   9740  C  CB  . GLU C 1 363 ? 8.365   65.837  -38.022 1.00 48.81  ? 363 GLU C CB  1 
ATOM   9741  C  CG  . GLU C 1 363 ? 8.665   66.681  -39.239 1.00 56.54  ? 363 GLU C CG  1 
ATOM   9742  C  CD  . GLU C 1 363 ? 9.734   67.702  -38.959 1.00 65.75  ? 363 GLU C CD  1 
ATOM   9743  O  OE1 . GLU C 1 363 ? 9.882   68.067  -37.775 1.00 68.50  ? 363 GLU C OE1 1 
ATOM   9744  O  OE2 . GLU C 1 363 ? 10.423  68.139  -39.910 1.00 70.05  ? 363 GLU C OE2 1 
ATOM   9745  N  N   . ASN C 1 364 ? 6.472   63.412  -36.437 1.00 48.17  ? 364 ASN C N   1 
ATOM   9746  C  CA  . ASN C 1 364 ? 6.471   62.546  -35.269 1.00 41.97  ? 364 ASN C CA  1 
ATOM   9747  C  C   . ASN C 1 364 ? 5.432   61.433  -35.365 1.00 39.53  ? 364 ASN C C   1 
ATOM   9748  O  O   . ASN C 1 364 ? 5.390   60.560  -34.483 1.00 35.75  ? 364 ASN C O   1 
ATOM   9749  C  CB  . ASN C 1 364 ? 6.220   63.380  -34.003 1.00 39.68  ? 364 ASN C CB  1 
ATOM   9750  C  CG  . ASN C 1 364 ? 7.478   64.060  -33.482 1.00 46.14  ? 364 ASN C CG  1 
ATOM   9751  O  OD1 . ASN C 1 364 ? 8.526   63.434  -33.368 1.00 50.67  ? 364 ASN C OD1 1 
ATOM   9752  N  ND2 . ASN C 1 364 ? 7.369   65.345  -33.139 1.00 43.62  ? 364 ASN C ND2 1 
ATOM   9753  N  N   . VAL C 1 365 ? 4.597   61.447  -36.399 1.00 37.57  ? 365 VAL C N   1 
ATOM   9754  C  CA  . VAL C 1 365 ? 3.611   60.397  -36.635 1.00 37.71  ? 365 VAL C CA  1 
ATOM   9755  C  C   . VAL C 1 365 ? 4.315   59.221  -37.305 1.00 40.04  ? 365 VAL C C   1 
ATOM   9756  O  O   . VAL C 1 365 ? 4.946   59.379  -38.355 1.00 35.53  ? 365 VAL C O   1 
ATOM   9757  C  CB  . VAL C 1 365 ? 2.451   60.916  -37.499 1.00 33.59  ? 365 VAL C CB  1 
ATOM   9758  C  CG1 . VAL C 1 365 ? 1.633   59.762  -38.064 1.00 34.16  ? 365 VAL C CG1 1 
ATOM   9759  C  CG2 . VAL C 1 365 ? 1.577   61.840  -36.699 1.00 35.98  ? 365 VAL C CG2 1 
ATOM   9760  N  N   . VAL C 1 366 ? 4.209   58.037  -36.704 1.00 34.08  ? 366 VAL C N   1 
ATOM   9761  C  CA  . VAL C 1 366 ? 4.957   56.875  -37.171 1.00 31.47  ? 366 VAL C CA  1 
ATOM   9762  C  C   . VAL C 1 366 ? 4.055   55.727  -37.611 1.00 35.27  ? 366 VAL C C   1 
ATOM   9763  O  O   . VAL C 1 366 ? 4.521   54.816  -38.317 1.00 33.28  ? 366 VAL C O   1 
ATOM   9764  C  CB  . VAL C 1 366 ? 5.933   56.394  -36.081 1.00 34.36  ? 366 VAL C CB  1 
ATOM   9765  C  CG1 . VAL C 1 366 ? 7.031   57.437  -35.822 1.00 31.73  ? 366 VAL C CG1 1 
ATOM   9766  C  CG2 . VAL C 1 366 ? 5.163   56.089  -34.796 1.00 37.25  ? 366 VAL C CG2 1 
ATOM   9767  N  N   . PHE C 1 367 ? 2.782   55.727  -37.232 1.00 35.91  ? 367 PHE C N   1 
ATOM   9768  C  CA  . PHE C 1 367 ? 1.880   54.636  -37.549 1.00 31.32  ? 367 PHE C CA  1 
ATOM   9769  C  C   . PHE C 1 367 ? 0.485   55.206  -37.512 1.00 26.72  ? 367 PHE C C   1 
ATOM   9770  O  O   . PHE C 1 367 ? 0.201   56.118  -36.727 1.00 30.17  ? 367 PHE C O   1 
ATOM   9771  C  CB  . PHE C 1 367 ? 2.029   53.479  -36.550 1.00 26.59  ? 367 PHE C CB  1 
ATOM   9772  C  CG  . PHE C 1 367 ? 1.345   52.207  -36.979 1.00 29.36  ? 367 PHE C CG  1 
ATOM   9773  C  CD1 . PHE C 1 367 ? 1.896   51.414  -37.970 1.00 33.17  ? 367 PHE C CD1 1 
ATOM   9774  C  CD2 . PHE C 1 367 ? 0.155   51.803  -36.378 1.00 27.50  ? 367 PHE C CD2 1 
ATOM   9775  C  CE1 . PHE C 1 367 ? 1.265   50.228  -38.360 1.00 35.68  ? 367 PHE C CE1 1 
ATOM   9776  C  CE2 . PHE C 1 367 ? -0.471  50.628  -36.753 1.00 32.31  ? 367 PHE C CE2 1 
ATOM   9777  C  CZ  . PHE C 1 367 ? 0.077   49.837  -37.738 1.00 30.89  ? 367 PHE C CZ  1 
ATOM   9778  N  N   . ILE C 1 368 ? -0.372  54.699  -38.380 1.00 22.92  ? 368 ILE C N   1 
ATOM   9779  C  CA  . ILE C 1 368 ? -1.751  55.164  -38.422 1.00 28.76  ? 368 ILE C CA  1 
ATOM   9780  C  C   . ILE C 1 368 ? -2.691  53.967  -38.358 1.00 30.57  ? 368 ILE C C   1 
ATOM   9781  O  O   . ILE C 1 368 ? -2.572  53.025  -39.152 1.00 34.63  ? 368 ILE C O   1 
ATOM   9782  C  CB  . ILE C 1 368 ? -2.019  56.039  -39.652 1.00 29.37  ? 368 ILE C CB  1 
ATOM   9783  C  CG1 . ILE C 1 368 ? -1.224  57.338  -39.470 1.00 31.86  ? 368 ILE C CG1 1 
ATOM   9784  C  CG2 . ILE C 1 368 ? -3.494  56.353  -39.755 1.00 28.08  ? 368 ILE C CG2 1 
ATOM   9785  C  CD1 . ILE C 1 368 ? -1.409  58.398  -40.553 1.00 29.35  ? 368 ILE C CD1 1 
ATOM   9786  N  N   . GLN C 1 369 ? -3.587  53.984  -37.375 1.00 31.64  ? 369 GLN C N   1 
ATOM   9787  C  CA  . GLN C 1 369 ? -4.688  53.035  -37.272 1.00 28.86  ? 369 GLN C CA  1 
ATOM   9788  C  C   . GLN C 1 369 ? -5.877  53.636  -38.008 1.00 32.49  ? 369 GLN C C   1 
ATOM   9789  O  O   . GLN C 1 369 ? -6.413  54.671  -37.594 1.00 29.42  ? 369 GLN C O   1 
ATOM   9790  C  CB  . GLN C 1 369 ? -5.030  52.769  -35.806 1.00 34.84  ? 369 GLN C CB  1 
ATOM   9791  C  CG  . GLN C 1 369 ? -4.272  51.593  -35.203 1.00 40.33  ? 369 GLN C CG  1 
ATOM   9792  C  CD  . GLN C 1 369 ? -4.310  51.547  -33.675 1.00 39.57  ? 369 GLN C CD  1 
ATOM   9793  O  OE1 . GLN C 1 369 ? -4.930  52.395  -33.012 1.00 40.01  ? 369 GLN C OE1 1 
ATOM   9794  N  NE2 . GLN C 1 369 ? -3.638  50.545  -33.110 1.00 32.72  ? 369 GLN C NE2 1 
ATOM   9795  N  N   . ALA C 1 370 ? -6.281  52.998  -39.109 1.00 29.41  ? 370 ALA C N   1 
ATOM   9796  C  CA  . ALA C 1 370 ? -7.416  53.446  -39.914 1.00 30.18  ? 370 ALA C CA  1 
ATOM   9797  C  C   . ALA C 1 370 ? -8.700  52.893  -39.306 1.00 30.91  ? 370 ALA C C   1 
ATOM   9798  O  O   . ALA C 1 370 ? -9.288  51.920  -39.786 1.00 27.91  ? 370 ALA C O   1 
ATOM   9799  C  CB  . ALA C 1 370 ? -7.262  53.005  -41.368 1.00 31.52  ? 370 ALA C CB  1 
ATOM   9800  N  N   . LYS C 1 371 ? -9.143  53.537  -38.228 1.00 27.58  ? 371 LYS C N   1 
ATOM   9801  C  CA  . LYS C 1 371 ? -10.431 53.210  -37.629 1.00 28.91  ? 371 LYS C CA  1 
ATOM   9802  C  C   . LYS C 1 371 ? -11.584 53.661  -38.524 1.00 28.68  ? 371 LYS C C   1 
ATOM   9803  O  O   . LYS C 1 371 ? -11.508 54.674  -39.234 1.00 30.76  ? 371 LYS C O   1 
ATOM   9804  C  CB  . LYS C 1 371 ? -10.561 53.869  -36.242 1.00 32.21  ? 371 LYS C CB  1 
ATOM   9805  C  CG  . LYS C 1 371 ? -11.863 53.523  -35.467 1.00 31.41  ? 371 LYS C CG  1 
ATOM   9806  C  CD  . LYS C 1 371 ? -11.592 52.714  -34.198 1.00 32.88  ? 371 LYS C CD  1 
ATOM   9807  C  CE  . LYS C 1 371 ? -11.402 53.629  -32.996 1.00 34.02  ? 371 LYS C CE  1 
ATOM   9808  N  NZ  . LYS C 1 371 ? -10.206 53.316  -32.190 1.00 41.78  ? 371 LYS C NZ  1 
ATOM   9809  N  N   . PHE C 1 372 ? -12.653 52.888  -38.482 1.00 19.36  ? 372 PHE C N   1 
ATOM   9810  C  CA  . PHE C 1 372 ? -13.905 53.186  -39.162 1.00 28.36  ? 372 PHE C CA  1 
ATOM   9811  C  C   . PHE C 1 372 ? -14.969 52.297  -38.539 1.00 26.49  ? 372 PHE C C   1 
ATOM   9812  O  O   . PHE C 1 372 ? -14.659 51.423  -37.730 1.00 30.18  ? 372 PHE C O   1 
ATOM   9813  C  CB  . PHE C 1 372 ? -13.802 52.940  -40.667 1.00 35.00  ? 372 PHE C CB  1 
ATOM   9814  C  CG  . PHE C 1 372 ? -13.750 51.483  -41.035 1.00 30.76  ? 372 PHE C CG  1 
ATOM   9815  C  CD1 . PHE C 1 372 ? -12.646 50.711  -40.711 1.00 28.33  ? 372 PHE C CD1 1 
ATOM   9816  C  CD2 . PHE C 1 372 ? -14.797 50.893  -41.704 1.00 29.42  ? 372 PHE C CD2 1 
ATOM   9817  C  CE1 . PHE C 1 372 ? -12.590 49.384  -41.074 1.00 30.27  ? 372 PHE C CE1 1 
ATOM   9818  C  CE2 . PHE C 1 372 ? -14.750 49.569  -42.054 1.00 30.70  ? 372 PHE C CE2 1 
ATOM   9819  C  CZ  . PHE C 1 372 ? -13.648 48.813  -41.738 1.00 26.24  ? 372 PHE C CZ  1 
ATOM   9820  N  N   . HIS C 1 373 ? -16.232 52.518  -38.928 1.00 27.84  ? 373 HIS C N   1 
ATOM   9821  C  CA  . HIS C 1 373 ? -17.359 51.840  -38.287 1.00 32.57  ? 373 HIS C CA  1 
ATOM   9822  C  C   . HIS C 1 373 ? -18.313 51.201  -39.281 1.00 29.51  ? 373 HIS C C   1 
ATOM   9823  O  O   . HIS C 1 373 ? -18.976 50.218  -38.946 1.00 28.39  ? 373 HIS C O   1 
ATOM   9824  C  CB  . HIS C 1 373 ? -18.142 52.817  -37.386 1.00 29.53  ? 373 HIS C CB  1 
ATOM   9825  C  CG  . HIS C 1 373 ? -17.271 53.562  -36.422 1.00 32.78  ? 373 HIS C CG  1 
ATOM   9826  N  ND1 . HIS C 1 373 ? -16.989 53.092  -35.160 1.00 32.95  ? 373 HIS C ND1 1 
ATOM   9827  C  CD2 . HIS C 1 373 ? -16.569 54.712  -36.558 1.00 34.62  ? 373 HIS C CD2 1 
ATOM   9828  C  CE1 . HIS C 1 373 ? -16.161 53.923  -34.555 1.00 32.94  ? 373 HIS C CE1 1 
ATOM   9829  N  NE2 . HIS C 1 373 ? -15.893 54.917  -35.380 1.00 31.47  ? 373 HIS C NE2 1 
ATOM   9830  N  N   . ASP C 1 374 ? -18.399 51.745  -40.495 1.00 28.40  ? 374 ASP C N   1 
ATOM   9831  C  CA  . ASP C 1 374 ? -19.490 51.387  -41.399 1.00 26.49  ? 374 ASP C CA  1 
ATOM   9832  C  C   . ASP C 1 374 ? -19.217 51.890  -42.815 1.00 33.60  ? 374 ASP C C   1 
ATOM   9833  O  O   . ASP C 1 374 ? -19.077 53.095  -43.037 1.00 31.09  ? 374 ASP C O   1 
ATOM   9834  C  CB  . ASP C 1 374 ? -20.806 51.964  -40.869 1.00 27.73  ? 374 ASP C CB  1 
ATOM   9835  C  CG  . ASP C 1 374 ? -22.032 51.376  -41.530 1.00 36.28  ? 374 ASP C CG  1 
ATOM   9836  O  OD1 . ASP C 1 374 ? -21.950 50.316  -42.197 1.00 34.49  ? 374 ASP C OD1 1 
ATOM   9837  O  OD2 . ASP C 1 374 ? -23.108 51.978  -41.347 1.00 40.88  ? 374 ASP C OD2 1 
ATOM   9838  N  N   . ILE C 1 375 ? -19.116 50.974  -43.774 1.00 32.65  ? 375 ILE C N   1 
ATOM   9839  C  CA  . ILE C 1 375 ? -18.970 51.313  -45.181 1.00 33.06  ? 375 ILE C CA  1 
ATOM   9840  C  C   . ILE C 1 375 ? -19.985 50.470  -45.928 1.00 31.09  ? 375 ILE C C   1 
ATOM   9841  O  O   . ILE C 1 375 ? -20.051 49.256  -45.720 1.00 32.49  ? 375 ILE C O   1 
ATOM   9842  C  CB  . ILE C 1 375 ? -17.536 51.059  -45.684 1.00 29.60  ? 375 ILE C CB  1 
ATOM   9843  C  CG1 . ILE C 1 375 ? -16.550 51.862  -44.836 1.00 28.22  ? 375 ILE C CG1 1 
ATOM   9844  C  CG2 . ILE C 1 375 ? -17.387 51.471  -47.130 1.00 29.65  ? 375 ILE C CG2 1 
ATOM   9845  C  CD1 . ILE C 1 375 ? -15.090 51.649  -45.169 1.00 29.45  ? 375 ILE C CD1 1 
ATOM   9846  N  N   . ASP C 1 376 ? -20.795 51.107  -46.773 1.00 34.79  ? 376 ASP C N   1 
ATOM   9847  C  CA  . ASP C 1 376 ? -21.922 50.416  -47.387 1.00 38.43  ? 376 ASP C CA  1 
ATOM   9848  C  C   . ASP C 1 376 ? -21.538 49.851  -48.766 1.00 36.22  ? 376 ASP C C   1 
ATOM   9849  O  O   . ASP C 1 376 ? -20.363 49.816  -49.145 1.00 34.65  ? 376 ASP C O   1 
ATOM   9850  C  CB  . ASP C 1 376 ? -23.136 51.353  -47.433 1.00 40.86  ? 376 ASP C CB  1 
ATOM   9851  C  CG  . ASP C 1 376 ? -22.951 52.527  -48.390 1.00 36.08  ? 376 ASP C CG  1 
ATOM   9852  O  OD1 . ASP C 1 376 ? -21.844 52.689  -48.937 1.00 38.48  ? 376 ASP C OD1 1 
ATOM   9853  O  OD2 . ASP C 1 376 ? -23.926 53.286  -48.597 1.00 38.71  ? 376 ASP C OD2 1 
ATOM   9854  N  N   . GLU C 1 377 ? -22.549 49.401  -49.527 1.00 36.05  ? 377 GLU C N   1 
ATOM   9855  C  CA  . GLU C 1 377 ? -22.374 48.777  -50.843 1.00 34.50  ? 377 GLU C CA  1 
ATOM   9856  C  C   . GLU C 1 377 ? -21.719 49.684  -51.882 1.00 39.29  ? 377 GLU C C   1 
ATOM   9857  O  O   . GLU C 1 377 ? -21.195 49.173  -52.882 1.00 39.14  ? 377 GLU C O   1 
ATOM   9858  C  CB  . GLU C 1 377 ? -23.733 48.334  -51.388 1.00 40.91  ? 377 GLU C CB  1 
ATOM   9859  C  CG  . GLU C 1 377 ? -24.364 47.169  -50.631 1.00 43.37  ? 377 GLU C CG  1 
ATOM   9860  C  CD  . GLU C 1 377 ? -24.738 47.545  -49.214 1.00 53.46  ? 377 GLU C CD  1 
ATOM   9861  O  OE1 . GLU C 1 377 ? -24.779 48.772  -48.915 1.00 44.51  ? 377 GLU C OE1 1 
ATOM   9862  O  OE2 . GLU C 1 377 ? -24.952 46.617  -48.399 1.00 51.77  ? 377 GLU C OE2 1 
ATOM   9863  N  N   . GLU C 1 378 ? -21.777 51.006  -51.711 1.00 33.99  ? 378 GLU C N   1 
ATOM   9864  C  CA  . GLU C 1 378 ? -21.199 51.938  -52.674 1.00 33.86  ? 378 GLU C CA  1 
ATOM   9865  C  C   . GLU C 1 378 ? -19.876 52.514  -52.206 1.00 34.79  ? 378 GLU C C   1 
ATOM   9866  O  O   . GLU C 1 378 ? -19.416 53.518  -52.759 1.00 35.30  ? 378 GLU C O   1 
ATOM   9867  C  CB  . GLU C 1 378 ? -22.164 53.089  -52.964 1.00 40.71  ? 378 GLU C CB  1 
ATOM   9868  C  CG  . GLU C 1 378 ? -23.501 52.665  -53.521 1.00 42.10  ? 378 GLU C CG  1 
ATOM   9869  C  CD  . GLU C 1 378 ? -23.386 52.202  -54.961 1.00 47.28  ? 378 GLU C CD  1 
ATOM   9870  O  OE1 . GLU C 1 378 ? -22.556 52.780  -55.711 1.00 42.04  ? 378 GLU C OE1 1 
ATOM   9871  O  OE2 . GLU C 1 378 ? -24.121 51.251  -55.324 1.00 45.71  ? 378 GLU C OE2 1 
ATOM   9872  N  N   . LEU C 1 379 ? -19.269 51.915  -51.189 1.00 36.00  ? 379 LEU C N   1 
ATOM   9873  C  CA  . LEU C 1 379 ? -18.057 52.443  -50.579 1.00 33.52  ? 379 LEU C CA  1 
ATOM   9874  C  C   . LEU C 1 379 ? -18.289 53.838  -49.991 1.00 31.40  ? 379 LEU C C   1 
ATOM   9875  O  O   . LEU C 1 379 ? -17.408 54.698  -50.025 1.00 28.83  ? 379 LEU C O   1 
ATOM   9876  C  CB  . LEU C 1 379 ? -16.897 52.447  -51.575 1.00 31.53  ? 379 LEU C CB  1 
ATOM   9877  C  CG  . LEU C 1 379 ? -16.492 51.064  -52.096 1.00 32.28  ? 379 LEU C CG  1 
ATOM   9878  C  CD1 . LEU C 1 379 ? -15.112 51.172  -52.759 1.00 28.91  ? 379 LEU C CD1 1 
ATOM   9879  C  CD2 . LEU C 1 379 ? -16.468 50.027  -50.969 1.00 31.17  ? 379 LEU C CD2 1 
ATOM   9880  N  N   . ASP C 1 380 ? -19.479 54.067  -49.429 1.00 33.13  ? 380 ASP C N   1 
ATOM   9881  C  CA  . ASP C 1 380 ? -19.738 55.287  -48.660 1.00 37.85  ? 380 ASP C CA  1 
ATOM   9882  C  C   . ASP C 1 380 ? -19.453 55.004  -47.189 1.00 33.11  ? 380 ASP C C   1 
ATOM   9883  O  O   . ASP C 1 380 ? -20.168 54.221  -46.550 1.00 29.29  ? 380 ASP C O   1 
ATOM   9884  C  CB  . ASP C 1 380 ? -21.173 55.780  -48.855 1.00 38.16  ? 380 ASP C CB  1 
ATOM   9885  C  CG  . ASP C 1 380 ? -21.511 57.000  -47.978 1.00 32.57  ? 380 ASP C CG  1 
ATOM   9886  O  OD1 . ASP C 1 380 ? -20.613 57.813  -47.691 1.00 42.05  ? 380 ASP C OD1 1 
ATOM   9887  O  OD2 . ASP C 1 380 ? -22.689 57.155  -47.595 1.00 35.77  ? 380 ASP C OD2 1 
ATOM   9888  N  N   . ASP C 1 381 ? -18.407 55.626  -46.653 1.00 34.70  ? 381 ASP C N   1 
ATOM   9889  C  CA  . ASP C 1 381 ? -18.151 55.554  -45.215 1.00 38.65  ? 381 ASP C CA  1 
ATOM   9890  C  C   . ASP C 1 381 ? -19.080 56.514  -44.483 1.00 40.31  ? 381 ASP C C   1 
ATOM   9891  O  O   . ASP C 1 381 ? -19.195 57.682  -44.868 1.00 39.06  ? 381 ASP C O   1 
ATOM   9892  C  CB  . ASP C 1 381 ? -16.695 55.902  -44.893 1.00 30.35  ? 381 ASP C CB  1 
ATOM   9893  C  CG  . ASP C 1 381 ? -16.309 55.543  -43.450 1.00 38.81  ? 381 ASP C CG  1 
ATOM   9894  O  OD1 . ASP C 1 381 ? -16.709 56.274  -42.508 1.00 33.17  ? 381 ASP C OD1 1 
ATOM   9895  O  OD2 . ASP C 1 381 ? -15.603 54.522  -43.267 1.00 35.35  ? 381 ASP C OD2 1 
ATOM   9896  N  N   . LYS C 1 382 ? -19.724 56.032  -43.412 1.00 39.08  ? 382 LYS C N   1 
ATOM   9897  C  CA  . LYS C 1 382 ? -20.774 56.788  -42.742 1.00 36.08  ? 382 LYS C CA  1 
ATOM   9898  C  C   . LYS C 1 382 ? -20.255 57.709  -41.643 1.00 39.48  ? 382 LYS C C   1 
ATOM   9899  O  O   . LYS C 1 382 ? -21.050 58.475  -41.080 1.00 36.49  ? 382 LYS C O   1 
ATOM   9900  C  CB  . LYS C 1 382 ? -21.819 55.844  -42.145 1.00 35.92  ? 382 LYS C CB  1 
ATOM   9901  C  CG  . LYS C 1 382 ? -22.353 54.798  -43.109 1.00 34.12  ? 382 LYS C CG  1 
ATOM   9902  C  CD  . LYS C 1 382 ? -22.796 55.415  -44.417 1.00 39.64  ? 382 LYS C CD  1 
ATOM   9903  C  CE  . LYS C 1 382 ? -23.826 54.521  -45.112 1.00 38.99  ? 382 LYS C CE  1 
ATOM   9904  N  NZ  . LYS C 1 382 ? -24.209 55.113  -46.426 1.00 38.26  ? 382 LYS C NZ  1 
ATOM   9905  N  N   . GLN C 1 383 ? -18.953 57.678  -41.341 1.00 31.66  ? 383 GLN C N   1 
ATOM   9906  C  CA  . GLN C 1 383 ? -18.434 58.408  -40.196 1.00 35.58  ? 383 GLN C CA  1 
ATOM   9907  C  C   . GLN C 1 383 ? -17.129 59.132  -40.496 1.00 34.23  ? 383 GLN C C   1 
ATOM   9908  O  O   . GLN C 1 383 ? -16.906 60.226  -39.970 1.00 35.55  ? 383 GLN C O   1 
ATOM   9909  C  CB  . GLN C 1 383 ? -18.221 57.455  -39.011 1.00 33.91  ? 383 GLN C CB  1 
ATOM   9910  C  CG  . GLN C 1 383 ? -19.446 57.252  -38.127 1.00 34.91  ? 383 GLN C CG  1 
ATOM   9911  C  CD  . GLN C 1 383 ? -20.404 56.212  -38.669 1.00 34.56  ? 383 GLN C CD  1 
ATOM   9912  O  OE1 . GLN C 1 383 ? -19.986 55.208  -39.237 1.00 36.33  ? 383 GLN C OE1 1 
ATOM   9913  N  NE2 . GLN C 1 383 ? -21.695 56.450  -38.499 1.00 38.13  ? 383 GLN C NE2 1 
ATOM   9914  N  N   . ILE C 1 384 ? -16.238 58.542  -41.282 1.00 31.33  ? 384 ILE C N   1 
ATOM   9915  C  CA  . ILE C 1 384 ? -14.882 59.062  -41.446 1.00 30.63  ? 384 ILE C CA  1 
ATOM   9916  C  C   . ILE C 1 384 ? -14.784 59.777  -42.789 1.00 31.97  ? 384 ILE C C   1 
ATOM   9917  O  O   . ILE C 1 384 ? -15.086 59.165  -43.821 1.00 37.00  ? 384 ILE C O   1 
ATOM   9918  C  CB  . ILE C 1 384 ? -13.811 57.963  -41.338 1.00 29.08  ? 384 ILE C CB  1 
ATOM   9919  C  CG1 . ILE C 1 384 ? -13.949 57.195  -40.032 1.00 36.68  ? 384 ILE C CG1 1 
ATOM   9920  C  CG2 . ILE C 1 384 ? -12.416 58.588  -41.391 1.00 34.14  ? 384 ILE C CG2 1 
ATOM   9921  C  CD1 . ILE C 1 384 ? -14.019 58.084  -38.810 1.00 33.67  ? 384 ILE C CD1 1 
ATOM   9922  N  N   . PRO C 1 385 ? -14.358 61.045  -42.819 1.00 33.93  ? 385 PRO C N   1 
ATOM   9923  C  CA  . PRO C 1 385 ? -14.086 61.728  -44.093 1.00 33.52  ? 385 PRO C CA  1 
ATOM   9924  C  C   . PRO C 1 385 ? -12.740 61.347  -44.689 1.00 30.30  ? 385 PRO C C   1 
ATOM   9925  O  O   . PRO C 1 385 ? -11.730 61.992  -44.394 1.00 33.54  ? 385 PRO C O   1 
ATOM   9926  C  CB  . PRO C 1 385 ? -14.109 63.204  -43.693 1.00 36.87  ? 385 PRO C CB  1 
ATOM   9927  C  CG  . PRO C 1 385 ? -13.653 63.194  -42.253 1.00 34.18  ? 385 PRO C CG  1 
ATOM   9928  C  CD  . PRO C 1 385 ? -14.190 61.935  -41.658 1.00 34.49  ? 385 PRO C CD  1 
ATOM   9929  N  N   . TRP C 1 386 ? -12.710 60.317  -45.545 1.00 37.44  ? 386 TRP C N   1 
ATOM   9930  C  CA  . TRP C 1 386 ? -11.439 59.739  -45.989 1.00 28.63  ? 386 TRP C CA  1 
ATOM   9931  C  C   . TRP C 1 386 ? -10.723 60.622  -47.010 1.00 30.78  ? 386 TRP C C   1 
ATOM   9932  O  O   . TRP C 1 386 ? -9.495  60.739  -46.965 1.00 32.84  ? 386 TRP C O   1 
ATOM   9933  C  CB  . TRP C 1 386 ? -11.680 58.334  -46.548 1.00 29.75  ? 386 TRP C CB  1 
ATOM   9934  C  CG  . TRP C 1 386 ? -11.862 57.311  -45.448 1.00 31.71  ? 386 TRP C CG  1 
ATOM   9935  C  CD1 . TRP C 1 386 ? -13.000 56.620  -45.144 1.00 26.25  ? 386 TRP C CD1 1 
ATOM   9936  C  CD2 . TRP C 1 386 ? -10.878 56.901  -44.493 1.00 27.95  ? 386 TRP C CD2 1 
ATOM   9937  N  NE1 . TRP C 1 386 ? -12.786 55.805  -44.065 1.00 29.16  ? 386 TRP C NE1 1 
ATOM   9938  C  CE2 . TRP C 1 386 ? -11.489 55.952  -43.647 1.00 31.24  ? 386 TRP C CE2 1 
ATOM   9939  C  CE3 . TRP C 1 386 ? -9.539  57.240  -44.274 1.00 26.22  ? 386 TRP C CE3 1 
ATOM   9940  C  CZ2 . TRP C 1 386 ? -10.808 55.341  -42.596 1.00 26.09  ? 386 TRP C CZ2 1 
ATOM   9941  C  CZ3 . TRP C 1 386 ? -8.866  56.633  -43.238 1.00 28.62  ? 386 TRP C CZ3 1 
ATOM   9942  C  CH2 . TRP C 1 386 ? -9.501  55.696  -42.408 1.00 28.05  ? 386 TRP C CH2 1 
ATOM   9943  N  N   . GLU C 1 387 ? -11.461 61.269  -47.920 1.00 33.50  ? 387 GLU C N   1 
ATOM   9944  C  CA  . GLU C 1 387 ? -10.811 62.121  -48.917 1.00 33.93  ? 387 GLU C CA  1 
ATOM   9945  C  C   . GLU C 1 387 ? -9.965  63.217  -48.283 1.00 34.54  ? 387 GLU C C   1 
ATOM   9946  O  O   . GLU C 1 387 ? -8.760  63.292  -48.586 1.00 32.10  ? 387 GLU C O   1 
ATOM   9947  C  CB  . GLU C 1 387 ? -11.856 62.690  -49.881 1.00 35.67  ? 387 GLU C CB  1 
ATOM   9948  C  CG  . GLU C 1 387 ? -12.606 61.663  -50.688 1.00 38.34  ? 387 GLU C CG  1 
ATOM   9949  C  CD  . GLU C 1 387 ? -14.005 61.449  -50.166 1.00 49.40  ? 387 GLU C CD  1 
ATOM   9950  O  OE1 . GLU C 1 387 ? -14.131 60.997  -49.001 1.00 41.80  ? 387 GLU C OE1 1 
ATOM   9951  O  OE2 . GLU C 1 387 ? -14.971 61.750  -50.917 1.00 50.54  ? 387 GLU C OE2 1 
ATOM   9952  N  N   . PRO C 1 388 ? -10.500 64.085  -47.403 1.00 34.25  ? 388 PRO C N   1 
ATOM   9953  C  CA  . PRO C 1 388 ? -9.630  65.090  -46.776 1.00 34.49  ? 388 PRO C CA  1 
ATOM   9954  C  C   . PRO C 1 388 ? -8.544  64.494  -45.911 1.00 34.50  ? 388 PRO C C   1 
ATOM   9955  O  O   . PRO C 1 388 ? -7.443  65.055  -45.840 1.00 36.11  ? 388 PRO C O   1 
ATOM   9956  C  CB  . PRO C 1 388 ? -10.604 65.934  -45.936 1.00 42.41  ? 388 PRO C CB  1 
ATOM   9957  C  CG  . PRO C 1 388 ? -11.809 65.101  -45.752 1.00 31.02  ? 388 PRO C CG  1 
ATOM   9958  C  CD  . PRO C 1 388 ? -11.906 64.265  -46.990 1.00 34.70  ? 388 PRO C CD  1 
ATOM   9959  N  N   . VAL C 1 389 ? -8.815  63.379  -45.236 1.00 38.14  ? 389 VAL C N   1 
ATOM   9960  C  CA  . VAL C 1 389 ? -7.806  62.797  -44.361 1.00 34.13  ? 389 VAL C CA  1 
ATOM   9961  C  C   . VAL C 1 389 ? -6.624  62.300  -45.178 1.00 31.06  ? 389 VAL C C   1 
ATOM   9962  O  O   . VAL C 1 389 ? -5.473  62.658  -44.917 1.00 27.99  ? 389 VAL C O   1 
ATOM   9963  C  CB  . VAL C 1 389 ? -8.428  61.683  -43.495 1.00 37.51  ? 389 VAL C CB  1 
ATOM   9964  C  CG1 . VAL C 1 389 ? -7.366  60.676  -43.032 1.00 34.55  ? 389 VAL C CG1 1 
ATOM   9965  C  CG2 . VAL C 1 389 ? -9.111  62.306  -42.308 1.00 34.00  ? 389 VAL C CG2 1 
ATOM   9966  N  N   . LEU C 1 390 ? -6.889  61.496  -46.206 1.00 34.17  ? 390 LEU C N   1 
ATOM   9967  C  CA  . LEU C 1 390 ? -5.779  61.010  -47.011 1.00 29.60  ? 390 LEU C CA  1 
ATOM   9968  C  C   . LEU C 1 390 ? -5.098  62.153  -47.757 1.00 32.71  ? 390 LEU C C   1 
ATOM   9969  O  O   . LEU C 1 390 ? -3.876  62.125  -47.953 1.00 32.87  ? 390 LEU C O   1 
ATOM   9970  C  CB  . LEU C 1 390 ? -6.276  59.912  -47.956 1.00 33.73  ? 390 LEU C CB  1 
ATOM   9971  C  CG  . LEU C 1 390 ? -7.052  58.798  -47.232 1.00 32.66  ? 390 LEU C CG  1 
ATOM   9972  C  CD1 . LEU C 1 390 ? -7.749  57.862  -48.200 1.00 31.11  ? 390 LEU C CD1 1 
ATOM   9973  C  CD2 . LEU C 1 390 ? -6.142  58.002  -46.312 1.00 28.42  ? 390 LEU C CD2 1 
ATOM   9974  N  N   . LYS C 1 391 ? -5.849  63.195  -48.125 1.00 32.60  ? 391 LYS C N   1 
ATOM   9975  C  CA  . LYS C 1 391 ? -5.214  64.347  -48.764 1.00 37.58  ? 391 LYS C CA  1 
ATOM   9976  C  C   . LYS C 1 391 ? -4.222  65.031  -47.833 1.00 38.32  ? 391 LYS C C   1 
ATOM   9977  O  O   . LYS C 1 391 ? -3.117  65.395  -48.254 1.00 42.61  ? 391 LYS C O   1 
ATOM   9978  C  CB  . LYS C 1 391 ? -6.264  65.347  -49.243 1.00 41.13  ? 391 LYS C CB  1 
ATOM   9979  C  CG  . LYS C 1 391 ? -5.751  66.222  -50.369 1.00 40.86  ? 391 LYS C CG  1 
ATOM   9980  C  CD  . LYS C 1 391 ? -6.317  67.612  -50.335 1.00 41.87  ? 391 LYS C CD  1 
ATOM   9981  C  CE  . LYS C 1 391 ? -5.339  68.582  -51.008 1.00 44.03  ? 391 LYS C CE  1 
ATOM   9982  N  NZ  . LYS C 1 391 ? -4.736  68.020  -52.261 1.00 48.49  ? 391 LYS C NZ  1 
ATOM   9983  N  N   . ALA C 1 392 ? -4.596  65.233  -46.568 1.00 36.89  ? 392 ALA C N   1 
ATOM   9984  C  CA  . ALA C 1 392 ? -3.668  65.859  -45.634 1.00 36.41  ? 392 ALA C CA  1 
ATOM   9985  C  C   . ALA C 1 392 ? -2.450  64.974  -45.393 1.00 39.50  ? 392 ALA C C   1 
ATOM   9986  O  O   . ALA C 1 392 ? -1.310  65.449  -45.424 1.00 44.50  ? 392 ALA C O   1 
ATOM   9987  C  CB  . ALA C 1 392 ? -4.378  66.186  -44.318 1.00 37.46  ? 392 ALA C CB  1 
ATOM   9988  N  N   . LEU C 1 393 ? -2.672  63.676  -45.151 1.00 39.95  ? 393 LEU C N   1 
ATOM   9989  C  CA  . LEU C 1 393 ? -1.554  62.782  -44.848 1.00 36.52  ? 393 LEU C CA  1 
ATOM   9990  C  C   . LEU C 1 393 ? -0.607  62.653  -46.039 1.00 39.30  ? 393 LEU C C   1 
ATOM   9991  O  O   . LEU C 1 393 ? 0.622   62.676  -45.880 1.00 33.44  ? 393 LEU C O   1 
ATOM   9992  C  CB  . LEU C 1 393 ? -2.085  61.412  -44.436 1.00 36.86  ? 393 LEU C CB  1 
ATOM   9993  C  CG  . LEU C 1 393 ? -2.977  61.311  -43.197 1.00 32.15  ? 393 LEU C CG  1 
ATOM   9994  C  CD1 . LEU C 1 393 ? -3.408  59.894  -43.052 1.00 25.48  ? 393 LEU C CD1 1 
ATOM   9995  C  CD2 . LEU C 1 393 ? -2.236  61.785  -41.949 1.00 29.00  ? 393 LEU C CD2 1 
ATOM   9996  N  N   . LYS C 1 394 ? -1.163  62.506  -47.242 1.00 40.47  ? 394 LYS C N   1 
ATOM   9997  C  CA  . LYS C 1 394 ? -0.344  62.507  -48.450 1.00 36.99  ? 394 LYS C CA  1 
ATOM   9998  C  C   . LYS C 1 394 ? 0.465   63.799  -48.561 1.00 36.61  ? 394 LYS C C   1 
ATOM   9999  O  O   . LYS C 1 394 ? 1.702   63.782  -48.488 1.00 35.77  ? 394 LYS C O   1 
ATOM   10000 C  CB  . LYS C 1 394 ? -1.243  62.298  -49.673 1.00 35.97  ? 394 LYS C CB  1 
ATOM   10001 C  CG  . LYS C 1 394 ? -0.507  62.345  -51.013 1.00 42.05  ? 394 LYS C CG  1 
ATOM   10002 C  CD  . LYS C 1 394 ? -1.375  61.802  -52.139 1.00 37.53  ? 394 LYS C CD  1 
ATOM   10003 C  CE  . LYS C 1 394 ? -0.557  61.395  -53.391 1.00 43.72  ? 394 LYS C CE  1 
ATOM   10004 N  NZ  . LYS C 1 394 ? -0.134  62.546  -54.239 1.00 41.38  ? 394 LYS C NZ  1 
ATOM   10005 N  N   . ASP C 1 395 ? -0.227  64.942  -48.677 1.00 40.02  ? 395 ASP C N   1 
ATOM   10006 C  CA  . ASP C 1 395 ? 0.455   66.222  -48.875 1.00 40.32  ? 395 ASP C CA  1 
ATOM   10007 C  C   . ASP C 1 395 ? 1.433   66.535  -47.755 1.00 41.88  ? 395 ASP C C   1 
ATOM   10008 O  O   . ASP C 1 395 ? 2.445   67.201  -47.991 1.00 39.46  ? 395 ASP C O   1 
ATOM   10009 C  CB  . ASP C 1 395 ? -0.554  67.357  -48.991 1.00 38.37  ? 395 ASP C CB  1 
ATOM   10010 C  CG  . ASP C 1 395 ? -1.419  67.239  -50.216 1.00 40.76  ? 395 ASP C CG  1 
ATOM   10011 O  OD1 . ASP C 1 395 ? -0.998  66.570  -51.179 1.00 42.60  ? 395 ASP C OD1 1 
ATOM   10012 O  OD2 . ASP C 1 395 ? -2.517  67.826  -50.226 1.00 41.12  ? 395 ASP C OD2 1 
ATOM   10013 N  N   . ALA C 1 396 ? 1.156   66.075  -46.530 1.00 39.67  ? 396 ALA C N   1 
ATOM   10014 C  CA  . ALA C 1 396 ? 2.118   66.288  -45.456 1.00 38.04  ? 396 ALA C CA  1 
ATOM   10015 C  C   . ALA C 1 396 ? 3.273   65.297  -45.495 1.00 33.82  ? 396 ALA C C   1 
ATOM   10016 O  O   . ALA C 1 396 ? 4.202   65.424  -44.687 1.00 33.67  ? 396 ALA C O   1 
ATOM   10017 C  CB  . ALA C 1 396 ? 1.425   66.228  -44.090 1.00 44.88  ? 396 ALA C CB  1 
ATOM   10018 N  N   . GLY C 1 397 ? 3.243   64.331  -46.409 1.00 34.66  ? 397 GLY C N   1 
ATOM   10019 C  CA  . GLY C 1 397 ? 4.365   63.451  -46.640 1.00 30.14  ? 397 GLY C CA  1 
ATOM   10020 C  C   . GLY C 1 397 ? 4.333   62.150  -45.872 1.00 34.52  ? 397 GLY C C   1 
ATOM   10021 O  O   . GLY C 1 397 ? 5.397   61.609  -45.559 1.00 33.98  ? 397 GLY C O   1 
ATOM   10022 N  N   . TYR C 1 398 ? 3.157   61.642  -45.535 1.00 33.84  ? 398 TYR C N   1 
ATOM   10023 C  CA  . TYR C 1 398 ? 3.074   60.410  -44.769 1.00 33.82  ? 398 TYR C CA  1 
ATOM   10024 C  C   . TYR C 1 398 ? 3.132   59.235  -45.729 1.00 35.93  ? 398 TYR C C   1 
ATOM   10025 O  O   . TYR C 1 398 ? 2.327   59.136  -46.662 1.00 37.77  ? 398 TYR C O   1 
ATOM   10026 C  CB  . TYR C 1 398 ? 1.803   60.339  -43.937 1.00 33.39  ? 398 TYR C CB  1 
ATOM   10027 C  CG  . TYR C 1 398 ? 1.771   59.088  -43.077 1.00 35.71  ? 398 TYR C CG  1 
ATOM   10028 C  CD1 . TYR C 1 398 ? 2.581   58.985  -41.964 1.00 34.00  ? 398 TYR C CD1 1 
ATOM   10029 C  CD2 . TYR C 1 398 ? 0.947   58.014  -43.388 1.00 29.05  ? 398 TYR C CD2 1 
ATOM   10030 C  CE1 . TYR C 1 398 ? 2.566   57.865  -41.178 1.00 30.31  ? 398 TYR C CE1 1 
ATOM   10031 C  CE2 . TYR C 1 398 ? 0.922   56.887  -42.588 1.00 26.49  ? 398 TYR C CE2 1 
ATOM   10032 C  CZ  . TYR C 1 398 ? 1.740   56.831  -41.483 1.00 31.12  ? 398 TYR C CZ  1 
ATOM   10033 O  OH  . TYR C 1 398 ? 1.760   55.724  -40.662 1.00 31.41  ? 398 TYR C OH  1 
ATOM   10034 N  N   . THR C 1 399 ? 4.083   58.349  -45.497 1.00 37.60  ? 399 THR C N   1 
ATOM   10035 C  CA  . THR C 1 399 ? 4.213   57.166  -46.322 1.00 32.81  ? 399 THR C CA  1 
ATOM   10036 C  C   . THR C 1 399 ? 4.254   55.893  -45.470 1.00 31.41  ? 399 THR C C   1 
ATOM   10037 O  O   . THR C 1 399 ? 4.562   54.821  -45.999 1.00 30.54  ? 399 THR C O   1 
ATOM   10038 C  CB  . THR C 1 399 ? 5.459   57.298  -47.200 1.00 31.29  ? 399 THR C CB  1 
ATOM   10039 O  OG1 . THR C 1 399 ? 6.611   57.433  -46.369 1.00 33.30  ? 399 THR C OG1 1 
ATOM   10040 C  CG2 . THR C 1 399 ? 5.356   58.567  -48.110 1.00 35.33  ? 399 THR C CG2 1 
ATOM   10041 N  N   . GLY C 1 400 ? 3.938   55.988  -44.172 1.00 34.71  ? 400 GLY C N   1 
ATOM   10042 C  CA  . GLY C 1 400 ? 3.843   54.836  -43.289 1.00 32.19  ? 400 GLY C CA  1 
ATOM   10043 C  C   . GLY C 1 400 ? 2.573   54.024  -43.488 1.00 30.28  ? 400 GLY C C   1 
ATOM   10044 O  O   . GLY C 1 400 ? 1.881   54.128  -44.503 1.00 32.69  ? 400 GLY C O   1 
ATOM   10045 N  N   . TYR C 1 401 ? 2.248   53.219  -42.477 1.00 33.12  ? 401 TYR C N   1 
ATOM   10046 C  CA  . TYR C 1 401 ? 1.133   52.286  -42.581 1.00 31.35  ? 401 TYR C CA  1 
ATOM   10047 C  C   . TYR C 1 401 ? -0.203  52.952  -42.266 1.00 32.37  ? 401 TYR C C   1 
ATOM   10048 O  O   . TYR C 1 401 ? -0.282  53.863  -41.430 1.00 30.87  ? 401 TYR C O   1 
ATOM   10049 C  CB  . TYR C 1 401 ? 1.362   51.099  -41.639 1.00 26.74  ? 401 TYR C CB  1 
ATOM   10050 C  CG  . TYR C 1 401 ? 1.972   49.896  -42.333 1.00 26.22  ? 401 TYR C CG  1 
ATOM   10051 C  CD1 . TYR C 1 401 ? 1.180   49.022  -43.060 1.00 27.71  ? 401 TYR C CD1 1 
ATOM   10052 C  CD2 . TYR C 1 401 ? 3.328   49.642  -42.271 1.00 28.95  ? 401 TYR C CD2 1 
ATOM   10053 C  CE1 . TYR C 1 401 ? 1.715   47.932  -43.696 1.00 27.83  ? 401 TYR C CE1 1 
ATOM   10054 C  CE2 . TYR C 1 401 ? 3.873   48.546  -42.912 1.00 27.33  ? 401 TYR C CE2 1 
ATOM   10055 C  CZ  . TYR C 1 401 ? 3.057   47.699  -43.626 1.00 27.57  ? 401 TYR C CZ  1 
ATOM   10056 O  OH  . TYR C 1 401 ? 3.570   46.598  -44.277 1.00 31.34  ? 401 TYR C OH  1 
ATOM   10057 N  N   . LEU C 1 402 ? -1.248  52.503  -42.973 1.00 26.75  ? 402 LEU C N   1 
ATOM   10058 C  CA  . LEU C 1 402 ? -2.650  52.669  -42.585 1.00 31.48  ? 402 LEU C CA  1 
ATOM   10059 C  C   . LEU C 1 402 ? -3.175  51.288  -42.201 1.00 26.69  ? 402 LEU C C   1 
ATOM   10060 O  O   . LEU C 1 402 ? -3.318  50.420  -43.066 1.00 27.72  ? 402 LEU C O   1 
ATOM   10061 C  CB  . LEU C 1 402 ? -3.503  53.229  -43.725 1.00 31.27  ? 402 LEU C CB  1 
ATOM   10062 C  CG  . LEU C 1 402 ? -3.451  54.664  -44.245 1.00 37.51  ? 402 LEU C CG  1 
ATOM   10063 C  CD1 . LEU C 1 402 ? -4.833  54.968  -44.774 1.00 40.95  ? 402 LEU C CD1 1 
ATOM   10064 C  CD2 . LEU C 1 402 ? -3.064  55.682  -43.180 1.00 24.16  ? 402 LEU C CD2 1 
ATOM   10065 N  N   . SER C 1 403 ? -3.506  51.087  -40.929 1.00 30.63  ? 403 SER C N   1 
ATOM   10066 C  CA  . SER C 1 403 ? -3.818  49.750  -40.427 1.00 27.70  ? 403 SER C CA  1 
ATOM   10067 C  C   . SER C 1 403 ? -5.281  49.663  -39.985 1.00 32.04  ? 403 SER C C   1 
ATOM   10068 O  O   . SER C 1 403 ? -5.690  50.334  -39.031 1.00 22.27  ? 403 SER C O   1 
ATOM   10069 C  CB  . SER C 1 403 ? -2.876  49.394  -39.281 1.00 30.61  ? 403 SER C CB  1 
ATOM   10070 O  OG  . SER C 1 403 ? -2.987  48.020  -38.939 1.00 32.34  ? 403 SER C OG  1 
ATOM   10071 N  N   . SER C 1 404 ? -6.052  48.800  -40.650 1.00 23.72  ? 404 SER C N   1 
ATOM   10072 C  CA  . SER C 1 404 ? -7.493  48.765  -40.440 1.00 27.63  ? 404 SER C CA  1 
ATOM   10073 C  C   . SER C 1 404 ? -7.846  48.453  -38.993 1.00 29.78  ? 404 SER C C   1 
ATOM   10074 O  O   . SER C 1 404 ? -7.386  47.459  -38.420 1.00 29.81  ? 404 SER C O   1 
ATOM   10075 C  CB  . SER C 1 404 ? -8.137  47.727  -41.352 1.00 27.25  ? 404 SER C CB  1 
ATOM   10076 O  OG  . SER C 1 404 ? -7.910  48.061  -42.700 1.00 30.62  ? 404 SER C OG  1 
ATOM   10077 N  N   . GLU C 1 405 ? -8.699  49.294  -38.414 1.00 32.90  ? 405 GLU C N   1 
ATOM   10078 C  CA  . GLU C 1 405 ? -9.299  49.041  -37.103 1.00 28.77  ? 405 GLU C CA  1 
ATOM   10079 C  C   . GLU C 1 405 ? -10.801 49.197  -37.256 1.00 27.01  ? 405 GLU C C   1 
ATOM   10080 O  O   . GLU C 1 405 ? -11.379 50.253  -36.988 1.00 31.56  ? 405 GLU C O   1 
ATOM   10081 C  CB  . GLU C 1 405 ? -8.736  49.977  -36.062 1.00 29.12  ? 405 GLU C CB  1 
ATOM   10082 C  CG  . GLU C 1 405 ? -7.553  49.387  -35.331 1.00 29.11  ? 405 GLU C CG  1 
ATOM   10083 C  CD  . GLU C 1 405 ? -7.270  50.096  -34.027 1.00 32.48  ? 405 GLU C CD  1 
ATOM   10084 O  OE1 . GLU C 1 405 ? -7.838  51.192  -33.797 1.00 31.71  ? 405 GLU C OE1 1 
ATOM   10085 O  OE2 . GLU C 1 405 ? -6.488  49.540  -33.221 1.00 36.64  ? 405 GLU C OE2 1 
ATOM   10086 N  N   . TYR C 1 406 ? -11.443 48.138  -37.696 1.00 25.10  ? 406 TYR C N   1 
ATOM   10087 C  CA  . TYR C 1 406 ? -12.892 48.135  -37.761 1.00 25.39  ? 406 TYR C CA  1 
ATOM   10088 C  C   . TYR C 1 406 ? -13.485 48.082  -36.362 1.00 31.29  ? 406 TYR C C   1 
ATOM   10089 O  O   . TYR C 1 406 ? -13.158 47.196  -35.567 1.00 29.07  ? 406 TYR C O   1 
ATOM   10090 C  CB  . TYR C 1 406 ? -13.376 46.941  -38.551 1.00 24.49  ? 406 TYR C CB  1 
ATOM   10091 C  CG  . TYR C 1 406 ? -14.865 46.711  -38.447 1.00 25.11  ? 406 TYR C CG  1 
ATOM   10092 C  CD1 . TYR C 1 406 ? -15.760 47.567  -39.086 1.00 26.02  ? 406 TYR C CD1 1 
ATOM   10093 C  CD2 . TYR C 1 406 ? -15.379 45.619  -37.764 1.00 21.82  ? 406 TYR C CD2 1 
ATOM   10094 C  CE1 . TYR C 1 406 ? -17.135 47.340  -39.031 1.00 29.35  ? 406 TYR C CE1 1 
ATOM   10095 C  CE2 . TYR C 1 406 ? -16.742 45.396  -37.694 1.00 21.72  ? 406 TYR C CE2 1 
ATOM   10096 C  CZ  . TYR C 1 406 ? -17.617 46.260  -38.325 1.00 25.13  ? 406 TYR C CZ  1 
ATOM   10097 O  OH  . TYR C 1 406 ? -18.979 46.037  -38.274 1.00 29.24  ? 406 TYR C OH  1 
ATOM   10098 N  N   . GLU C 1 407 ? -14.377 49.018  -36.080 1.00 29.60  ? 407 GLU C N   1 
ATOM   10099 C  CA  . GLU C 1 407 ? -15.048 49.155  -34.796 1.00 31.84  ? 407 GLU C CA  1 
ATOM   10100 C  C   . GLU C 1 407 ? -16.524 49.376  -35.037 1.00 30.33  ? 407 GLU C C   1 
ATOM   10101 O  O   . GLU C 1 407 ? -17.164 50.232  -34.420 1.00 31.57  ? 407 GLU C O   1 
ATOM   10102 C  CB  . GLU C 1 407 ? -14.453 50.300  -33.984 1.00 33.82  ? 407 GLU C CB  1 
ATOM   10103 C  CG  . GLU C 1 407 ? -14.415 50.108  -32.461 1.00 34.76  ? 407 GLU C CG  1 
ATOM   10104 C  CD  . GLU C 1 407 ? -13.695 51.262  -31.775 1.00 36.97  ? 407 GLU C CD  1 
ATOM   10105 O  OE1 . GLU C 1 407 ? -14.216 52.399  -31.833 1.00 37.43  ? 407 GLU C OE1 1 
ATOM   10106 O  OE2 . GLU C 1 407 ? -12.597 51.057  -31.208 1.00 40.27  ? 407 GLU C OE2 1 
ATOM   10107 N  N   . GLY C 1 408 ? -17.065 48.661  -36.016 1.00 29.71  ? 408 GLY C N   1 
ATOM   10108 C  CA  . GLY C 1 408 ? -18.478 48.697  -36.295 1.00 28.38  ? 408 GLY C CA  1 
ATOM   10109 C  C   . GLY C 1 408 ? -19.219 47.676  -35.474 1.00 28.76  ? 408 GLY C C   1 
ATOM   10110 O  O   . GLY C 1 408 ? -18.687 47.071  -34.540 1.00 28.19  ? 408 GLY C O   1 
ATOM   10111 N  N   . GLU C 1 409 ? -20.491 47.514  -35.817 1.00 30.87  ? 409 GLU C N   1 
ATOM   10112 C  CA  . GLU C 1 409 ? -21.310 46.492  -35.197 1.00 36.01  ? 409 GLU C CA  1 
ATOM   10113 C  C   . GLU C 1 409 ? -20.612 45.144  -35.313 1.00 40.59  ? 409 GLU C C   1 
ATOM   10114 O  O   . GLU C 1 409 ? -20.038 44.815  -36.356 1.00 38.07  ? 409 GLU C O   1 
ATOM   10115 C  CB  . GLU C 1 409 ? -22.678 46.458  -35.876 1.00 42.44  ? 409 GLU C CB  1 
ATOM   10116 C  CG  . GLU C 1 409 ? -23.807 46.043  -34.977 1.00 50.17  ? 409 GLU C CG  1 
ATOM   10117 C  CD  . GLU C 1 409 ? -25.127 46.091  -35.689 1.00 57.38  ? 409 GLU C CD  1 
ATOM   10118 O  OE1 . GLU C 1 409 ? -25.135 45.835  -36.911 1.00 65.07  ? 409 GLU C OE1 1 
ATOM   10119 O  OE2 . GLU C 1 409 ? -26.148 46.389  -35.035 1.00 63.81  ? 409 GLU C OE2 1 
ATOM   10120 N  N   . ARG C 1 410 ? -20.637 44.376  -34.224 1.00 38.28  ? 410 ARG C N   1 
ATOM   10121 C  CA  . ARG C 1 410 ? -19.923 43.102  -34.150 1.00 35.89  ? 410 ARG C CA  1 
ATOM   10122 C  C   . ARG C 1 410 ? -20.786 41.918  -34.567 1.00 30.39  ? 410 ARG C C   1 
ATOM   10123 O  O   . ARG C 1 410 ? -20.765 40.897  -33.879 1.00 31.72  ? 410 ARG C O   1 
ATOM   10124 C  CB  . ARG C 1 410 ? -19.383 42.900  -32.734 1.00 33.11  ? 410 ARG C CB  1 
ATOM   10125 C  CG  . ARG C 1 410 ? -18.387 43.962  -32.248 1.00 34.73  ? 410 ARG C CG  1 
ATOM   10126 C  CD  . ARG C 1 410 ? -17.091 43.892  -33.003 1.00 26.47  ? 410 ARG C CD  1 
ATOM   10127 N  NE  . ARG C 1 410 ? -16.154 44.957  -32.663 1.00 30.37  ? 410 ARG C NE  1 
ATOM   10128 C  CZ  . ARG C 1 410 ? -15.119 45.285  -33.427 1.00 29.94  ? 410 ARG C CZ  1 
ATOM   10129 N  NH1 . ARG C 1 410 ? -14.885 44.669  -34.571 1.00 26.25  ? 410 ARG C NH1 1 
ATOM   10130 N  NH2 . ARG C 1 410 ? -14.285 46.235  -33.025 1.00 32.99  ? 410 ARG C NH2 1 
ATOM   10131 N  N   . GLU C 1 411 ? -21.573 42.022  -35.643 1.00 33.62  ? 411 GLU C N   1 
ATOM   10132 C  CA  . GLU C 1 411 ? -22.309 40.862  -36.144 1.00 36.81  ? 411 GLU C CA  1 
ATOM   10133 C  C   . GLU C 1 411 ? -21.326 39.817  -36.649 1.00 34.40  ? 411 GLU C C   1 
ATOM   10134 O  O   . GLU C 1 411 ? -20.397 40.162  -37.395 1.00 30.64  ? 411 GLU C O   1 
ATOM   10135 C  CB  . GLU C 1 411 ? -23.232 41.199  -37.321 1.00 37.13  ? 411 GLU C CB  1 
ATOM   10136 C  CG  . GLU C 1 411 ? -24.289 42.246  -37.135 1.00 49.31  ? 411 GLU C CG  1 
ATOM   10137 C  CD  . GLU C 1 411 ? -25.175 42.334  -38.380 1.00 57.27  ? 411 GLU C CD  1 
ATOM   10138 O  OE1 . GLU C 1 411 ? -24.904 41.582  -39.347 1.00 49.20  ? 411 GLU C OE1 1 
ATOM   10139 O  OE2 . GLU C 1 411 ? -26.130 43.140  -38.397 1.00 57.84  ? 411 GLU C OE2 1 
ATOM   10140 N  N   . PRO C 1 412 ? -21.519 38.521  -36.313 1.00 31.27  ? 412 PRO C N   1 
ATOM   10141 C  CA  . PRO C 1 412 ? -20.656 37.476  -36.847 1.00 31.09  ? 412 PRO C CA  1 
ATOM   10142 C  C   . PRO C 1 412 ? -20.319 37.647  -38.335 1.00 29.28  ? 412 PRO C C   1 
ATOM   10143 O  O   . PRO C 1 412 ? -21.241 37.747  -39.105 1.00 31.90  ? 412 PRO C O   1 
ATOM   10144 C  CB  . PRO C 1 412 ? -21.492 36.218  -36.624 1.00 34.34  ? 412 PRO C CB  1 
ATOM   10145 C  CG  . PRO C 1 412 ? -22.234 36.489  -35.350 1.00 28.74  ? 412 PRO C CG  1 
ATOM   10146 C  CD  . PRO C 1 412 ? -22.540 37.968  -35.407 1.00 32.56  ? 412 PRO C CD  1 
ATOM   10147 N  N   . TRP C 1 413 ? -19.034 37.746  -38.663 1.00 26.30  ? 413 TRP C N   1 
ATOM   10148 C  CA  . TRP C 1 413 ? -18.538 37.800  -40.069 1.00 30.94  ? 413 TRP C CA  1 
ATOM   10149 C  C   . TRP C 1 413 ? -18.659 39.179  -40.733 1.00 31.23  ? 413 TRP C C   1 
ATOM   10150 O  O   . TRP C 1 413 ? -18.053 39.364  -41.789 1.00 25.25  ? 413 TRP C O   1 
ATOM   10151 C  CB  . TRP C 1 413 ? -19.248 36.752  -40.946 1.00 27.90  ? 413 TRP C CB  1 
ATOM   10152 C  CG  . TRP C 1 413 ? -18.928 35.345  -40.550 1.00 27.09  ? 413 TRP C CG  1 
ATOM   10153 C  CD1 . TRP C 1 413 ? -17.750 34.687  -40.742 1.00 28.38  ? 413 TRP C CD1 1 
ATOM   10154 C  CD2 . TRP C 1 413 ? -19.789 34.423  -39.859 1.00 27.72  ? 413 TRP C CD2 1 
ATOM   10155 N  NE1 . TRP C 1 413 ? -17.821 33.422  -40.231 1.00 27.84  ? 413 TRP C NE1 1 
ATOM   10156 C  CE2 . TRP C 1 413 ? -19.058 33.231  -39.682 1.00 26.68  ? 413 TRP C CE2 1 
ATOM   10157 C  CE3 . TRP C 1 413 ? -21.101 34.483  -39.384 1.00 27.33  ? 413 TRP C CE3 1 
ATOM   10158 C  CZ2 . TRP C 1 413 ? -19.596 32.117  -39.045 1.00 29.59  ? 413 TRP C CZ2 1 
ATOM   10159 C  CZ3 . TRP C 1 413 ? -21.631 33.384  -38.748 1.00 29.31  ? 413 TRP C CZ3 1 
ATOM   10160 C  CH2 . TRP C 1 413 ? -20.885 32.220  -38.578 1.00 31.55  ? 413 TRP C CH2 1 
ATOM   10161 N  N   . ARG C 1 414 ? -19.358 40.119  -40.113 1.00 31.22  ? 414 ARG C N   1 
ATOM   10162 C  CA  . ARG C 1 414 ? -19.501 41.445  -40.759 1.00 30.20  ? 414 ARG C CA  1 
ATOM   10163 C  C   . ARG C 1 414 ? -18.125 42.064  -40.965 1.00 28.79  ? 414 ARG C C   1 
ATOM   10164 O  O   . ARG C 1 414 ? -17.911 42.688  -42.004 1.00 24.80  ? 414 ARG C O   1 
ATOM   10165 C  CB  . ARG C 1 414 ? -20.386 42.372  -39.920 1.00 36.08  ? 414 ARG C CB  1 
ATOM   10166 C  CG  . ARG C 1 414 ? -20.755 43.676  -40.609 1.00 38.74  ? 414 ARG C CG  1 
ATOM   10167 C  CD  . ARG C 1 414 ? -21.508 44.593  -39.665 1.00 46.50  ? 414 ARG C CD  1 
ATOM   10168 N  NE  . ARG C 1 414 ? -21.402 45.986  -40.059 1.00 36.96  ? 414 ARG C NE  1 
ATOM   10169 C  CZ  . ARG C 1 414 ? -22.151 46.554  -40.993 1.00 43.88  ? 414 ARG C CZ  1 
ATOM   10170 N  NH1 . ARG C 1 414 ? -22.919 45.810  -41.769 1.00 39.99  ? 414 ARG C NH1 1 
ATOM   10171 N  NH2 . ARG C 1 414 ? -22.132 47.866  -41.146 1.00 38.32  ? 414 ARG C NH2 1 
ATOM   10172 N  N   . SER C 1 415 ? -17.221 41.838  -40.023 1.00 25.90  ? 415 SER C N   1 
ATOM   10173 C  CA  . SER C 1 415 ? -15.952 42.534  -40.101 1.00 25.93  ? 415 SER C CA  1 
ATOM   10174 C  C   . SER C 1 415 ? -15.164 42.182  -41.351 1.00 23.93  ? 415 SER C C   1 
ATOM   10175 O  O   . SER C 1 415 ? -14.314 42.969  -41.768 1.00 33.05  ? 415 SER C O   1 
ATOM   10176 C  CB  . SER C 1 415 ? -15.129 42.221  -38.868 1.00 28.62  ? 415 SER C CB  1 
ATOM   10177 O  OG  . SER C 1 415 ? -14.889 40.828  -38.824 1.00 27.16  ? 415 SER C OG  1 
ATOM   10178 N  N   . ILE C 1 416 ? -15.418 41.042  -41.984 1.00 29.12  ? 416 ILE C N   1 
ATOM   10179 C  CA  . ILE C 1 416 ? -14.565 40.660  -43.107 1.00 24.70  ? 416 ILE C CA  1 
ATOM   10180 C  C   . ILE C 1 416 ? -14.859 41.532  -44.319 1.00 26.17  ? 416 ILE C C   1 
ATOM   10181 O  O   . ILE C 1 416 ? -13.946 42.132  -44.897 1.00 28.00  ? 416 ILE C O   1 
ATOM   10182 C  CB  . ILE C 1 416 ? -14.714 39.165  -43.438 1.00 28.60  ? 416 ILE C CB  1 
ATOM   10183 C  CG1 . ILE C 1 416 ? -13.896 38.300  -42.459 1.00 30.30  ? 416 ILE C CG1 1 
ATOM   10184 C  CG2 . ILE C 1 416 ? -14.248 38.904  -44.842 1.00 25.23  ? 416 ILE C CG2 1 
ATOM   10185 C  CD1 . ILE C 1 416 ? -14.527 36.970  -42.155 1.00 20.34  ? 416 ILE C CD1 1 
ATOM   10186 N  N   . GLU C 1 417 ? -16.136 41.589  -44.731 1.00 26.09  ? 417 GLU C N   1 
ATOM   10187 C  CA  . GLU C 1 417 ? -16.574 42.491  -45.796 1.00 28.79  ? 417 GLU C CA  1 
ATOM   10188 C  C   . GLU C 1 417 ? -16.191 43.926  -45.486 1.00 31.57  ? 417 GLU C C   1 
ATOM   10189 O  O   . GLU C 1 417 ? -15.741 44.670  -46.370 1.00 32.18  ? 417 GLU C O   1 
ATOM   10190 C  CB  . GLU C 1 417 ? -18.093 42.396  -45.981 1.00 25.47  ? 417 GLU C CB  1 
ATOM   10191 C  CG  . GLU C 1 417 ? -18.578 41.687  -47.243 1.00 34.74  ? 417 GLU C CG  1 
ATOM   10192 C  CD  . GLU C 1 417 ? -17.795 42.095  -48.497 1.00 35.04  ? 417 GLU C CD  1 
ATOM   10193 O  OE1 . GLU C 1 417 ? -18.020 43.226  -48.996 1.00 35.24  ? 417 GLU C OE1 1 
ATOM   10194 O  OE2 . GLU C 1 417 ? -16.993 41.273  -49.009 1.00 34.94  ? 417 GLU C OE2 1 
ATOM   10195 N  N   . GLN C 1 418 ? -16.348 44.328  -44.222 1.00 30.41  ? 418 GLN C N   1 
ATOM   10196 C  CA  . GLN C 1 418 ? -16.095 45.711  -43.863 1.00 25.94  ? 418 GLN C CA  1 
ATOM   10197 C  C   . GLN C 1 418 ? -14.643 46.085  -44.098 1.00 28.56  ? 418 GLN C C   1 
ATOM   10198 O  O   . GLN C 1 418 ? -14.360 47.108  -44.728 1.00 31.79  ? 418 GLN C O   1 
ATOM   10199 C  CB  . GLN C 1 418 ? -16.521 45.946  -42.423 1.00 24.42  ? 418 GLN C CB  1 
ATOM   10200 C  CG  . GLN C 1 418 ? -18.034 45.879  -42.272 1.00 30.54  ? 418 GLN C CG  1 
ATOM   10201 C  CD  . GLN C 1 418 ? -18.726 47.062  -42.942 1.00 34.53  ? 418 GLN C CD  1 
ATOM   10202 O  OE1 . GLN C 1 418 ? -18.409 48.218  -42.651 1.00 31.79  ? 418 GLN C OE1 1 
ATOM   10203 N  NE2 . GLN C 1 418 ? -19.669 46.778  -43.842 1.00 32.50  ? 418 GLN C NE2 1 
ATOM   10204 N  N   . VAL C 1 419 ? -13.702 45.260  -43.624 1.00 20.97  ? 419 VAL C N   1 
ATOM   10205 C  CA  . VAL C 1 419 ? -12.297 45.586  -43.838 1.00 23.02  ? 419 VAL C CA  1 
ATOM   10206 C  C   . VAL C 1 419 ? -11.964 45.605  -45.338 1.00 26.19  ? 419 VAL C C   1 
ATOM   10207 O  O   . VAL C 1 419 ? -11.202 46.467  -45.798 1.00 27.45  ? 419 VAL C O   1 
ATOM   10208 C  CB  . VAL C 1 419 ? -11.392 44.624  -43.051 1.00 26.94  ? 419 VAL C CB  1 
ATOM   10209 C  CG1 . VAL C 1 419 ? -9.936  44.908  -43.363 1.00 28.25  ? 419 VAL C CG1 1 
ATOM   10210 C  CG2 . VAL C 1 419 ? -11.604 44.804  -41.559 1.00 25.76  ? 419 VAL C CG2 1 
ATOM   10211 N  N   . ARG C 1 420 ? -12.543 44.675  -46.125 1.00 24.66  ? 420 ARG C N   1 
ATOM   10212 C  CA  . ARG C 1 420 ? -12.302 44.662  -47.573 1.00 22.66  ? 420 ARG C CA  1 
ATOM   10213 C  C   . ARG C 1 420 ? -12.768 45.966  -48.207 1.00 26.53  ? 420 ARG C C   1 
ATOM   10214 O  O   . ARG C 1 420 ? -12.022 46.621  -48.955 1.00 28.17  ? 420 ARG C O   1 
ATOM   10215 C  CB  . ARG C 1 420 ? -13.026 43.483  -48.234 1.00 24.46  ? 420 ARG C CB  1 
ATOM   10216 C  CG  . ARG C 1 420 ? -12.548 42.096  -47.829 1.00 24.21  ? 420 ARG C CG  1 
ATOM   10217 C  CD  . ARG C 1 420 ? -13.372 41.030  -48.536 1.00 31.41  ? 420 ARG C CD  1 
ATOM   10218 N  NE  . ARG C 1 420 ? -12.954 40.902  -49.927 1.00 26.38  ? 420 ARG C NE  1 
ATOM   10219 C  CZ  . ARG C 1 420 ? -11.808 40.348  -50.309 1.00 32.32  ? 420 ARG C CZ  1 
ATOM   10220 N  NH1 . ARG C 1 420 ? -10.961 39.830  -49.427 1.00 25.31  ? 420 ARG C NH1 1 
ATOM   10221 N  NH2 . ARG C 1 420 ? -11.499 40.316  -51.612 1.00 31.70  ? 420 ARG C NH2 1 
ATOM   10222 N  N   . ARG C 1 421 ? -14.012 46.352  -47.910 1.00 27.17  ? 421 ARG C N   1 
ATOM   10223 C  CA  . ARG C 1 421 ? -14.541 47.640  -48.340 1.00 30.98  ? 421 ARG C CA  1 
ATOM   10224 C  C   . ARG C 1 421 ? -13.615 48.804  -47.973 1.00 30.03  ? 421 ARG C C   1 
ATOM   10225 O  O   . ARG C 1 421 ? -13.390 49.702  -48.792 1.00 28.69  ? 421 ARG C O   1 
ATOM   10226 C  CB  . ARG C 1 421 ? -15.942 47.815  -47.753 1.00 29.75  ? 421 ARG C CB  1 
ATOM   10227 C  CG  . ARG C 1 421 ? -16.951 46.941  -48.458 1.00 29.27  ? 421 ARG C CG  1 
ATOM   10228 C  CD  . ARG C 1 421 ? -18.286 46.961  -47.800 1.00 29.07  ? 421 ARG C CD  1 
ATOM   10229 N  NE  . ARG C 1 421 ? -19.056 45.785  -48.169 1.00 31.34  ? 421 ARG C NE  1 
ATOM   10230 C  CZ  . ARG C 1 421 ? -20.361 45.664  -47.985 1.00 29.63  ? 421 ARG C CZ  1 
ATOM   10231 N  NH1 . ARG C 1 421 ? -21.074 46.634  -47.439 1.00 32.65  ? 421 ARG C NH1 1 
ATOM   10232 N  NH2 . ARG C 1 421 ? -20.967 44.546  -48.363 1.00 30.37  ? 421 ARG C NH2 1 
ATOM   10233 N  N   . GLN C 1 422 ? -13.034 48.794  -46.768 1.00 31.62  ? 422 GLN C N   1 
ATOM   10234 C  CA  . GLN C 1 422 ? -12.143 49.898  -46.388 1.00 30.89  ? 422 GLN C CA  1 
ATOM   10235 C  C   . GLN C 1 422 ? -10.914 49.975  -47.295 1.00 35.12  ? 422 GLN C C   1 
ATOM   10236 O  O   . GLN C 1 422 ? -10.519 51.062  -47.747 1.00 30.59  ? 422 GLN C O   1 
ATOM   10237 C  CB  . GLN C 1 422 ? -11.686 49.782  -44.927 1.00 27.27  ? 422 GLN C CB  1 
ATOM   10238 C  CG  . GLN C 1 422 ? -11.019 51.097  -44.446 1.00 30.53  ? 422 GLN C CG  1 
ATOM   10239 C  CD  . GLN C 1 422 ? -10.221 51.008  -43.133 1.00 34.07  ? 422 GLN C CD  1 
ATOM   10240 O  OE1 . GLN C 1 422 ? -9.431  50.086  -42.919 1.00 34.66  ? 422 GLN C OE1 1 
ATOM   10241 N  NE2 . GLN C 1 422 ? -10.401 52.000  -42.270 1.00 30.38  ? 422 GLN C NE2 1 
ATOM   10242 N  N   . HIS C 1 423 ? -10.262 48.834  -47.527 1.00 32.46  ? 423 HIS C N   1 
ATOM   10243 C  CA  . HIS C 1 423 ? -9.057  48.825  -48.346 1.00 26.87  ? 423 HIS C CA  1 
ATOM   10244 C  C   . HIS C 1 423 ? -9.360  49.222  -49.783 1.00 26.53  ? 423 HIS C C   1 
ATOM   10245 O  O   . HIS C 1 423 ? -8.587  49.966  -50.407 1.00 31.52  ? 423 HIS C O   1 
ATOM   10246 C  CB  . HIS C 1 423 ? -8.405  47.444  -48.272 1.00 32.00  ? 423 HIS C CB  1 
ATOM   10247 C  CG  . HIS C 1 423 ? -7.608  47.246  -47.024 1.00 25.19  ? 423 HIS C CG  1 
ATOM   10248 N  ND1 . HIS C 1 423 ? -6.234  47.357  -46.995 1.00 23.94  ? 423 HIS C ND1 1 
ATOM   10249 C  CD2 . HIS C 1 423 ? -7.997  47.007  -45.749 1.00 25.13  ? 423 HIS C CD2 1 
ATOM   10250 C  CE1 . HIS C 1 423 ? -5.809  47.173  -45.757 1.00 26.90  ? 423 HIS C CE1 1 
ATOM   10251 N  NE2 . HIS C 1 423 ? -6.859  46.955  -44.985 1.00 26.90  ? 423 HIS C NE2 1 
ATOM   10252 N  N   . SER C 1 424 ? -10.477 48.746  -50.321 1.00 27.29  ? 424 SER C N   1 
ATOM   10253 C  CA  . SER C 1 424 ? -10.890 49.185  -51.650 1.00 31.12  ? 424 SER C CA  1 
ATOM   10254 C  C   . SER C 1 424 ? -11.128 50.691  -51.680 1.00 31.08  ? 424 SER C C   1 
ATOM   10255 O  O   . SER C 1 424 ? -10.765 51.369  -52.655 1.00 29.30  ? 424 SER C O   1 
ATOM   10256 C  CB  . SER C 1 424 ? -12.147 48.434  -52.087 1.00 30.03  ? 424 SER C CB  1 
ATOM   10257 O  OG  . SER C 1 424 ? -12.559 48.876  -53.375 1.00 34.68  ? 424 SER C OG  1 
ATOM   10258 N  N   . LEU C 1 425 ? -11.708 51.241  -50.609 1.00 28.24  ? 425 LEU C N   1 
ATOM   10259 C  CA  . LEU C 1 425 ? -12.033 52.662  -50.613 1.00 28.47  ? 425 LEU C CA  1 
ATOM   10260 C  C   . LEU C 1 425 ? -10.778 53.515  -50.545 1.00 29.39  ? 425 LEU C C   1 
ATOM   10261 O  O   . LEU C 1 425 ? -10.597 54.437  -51.349 1.00 30.16  ? 425 LEU C O   1 
ATOM   10262 C  CB  . LEU C 1 425 ? -12.960 53.010  -49.450 1.00 34.02  ? 425 LEU C CB  1 
ATOM   10263 C  CG  . LEU C 1 425 ? -13.357 54.497  -49.440 1.00 32.90  ? 425 LEU C CG  1 
ATOM   10264 C  CD1 . LEU C 1 425 ? -14.082 54.846  -50.752 1.00 26.04  ? 425 LEU C CD1 1 
ATOM   10265 C  CD2 . LEU C 1 425 ? -14.201 54.887  -48.224 1.00 30.20  ? 425 LEU C CD2 1 
ATOM   10266 N  N   . ILE C 1 426 ? -9.905  53.252  -49.581 1.00 26.68  ? 426 ILE C N   1 
ATOM   10267 C  CA  . ILE C 1 426 ? -8.817  54.213  -49.434 1.00 33.49  ? 426 ILE C CA  1 
ATOM   10268 C  C   . ILE C 1 426 ? -7.800  54.043  -50.562 1.00 32.25  ? 426 ILE C C   1 
ATOM   10269 O  O   . ILE C 1 426 ? -7.165  55.013  -50.985 1.00 32.72  ? 426 ILE C O   1 
ATOM   10270 C  CB  . ILE C 1 426 ? -8.163  54.121  -48.039 1.00 30.66  ? 426 ILE C CB  1 
ATOM   10271 C  CG1 . ILE C 1 426 ? -7.276  52.905  -47.918 1.00 37.55  ? 426 ILE C CG1 1 
ATOM   10272 C  CG2 . ILE C 1 426 ? -9.224  54.042  -46.954 1.00 27.92  ? 426 ILE C CG2 1 
ATOM   10273 C  CD1 . ILE C 1 426 ? -6.804  52.639  -46.480 1.00 39.08  ? 426 ILE C CD1 1 
ATOM   10274 N  N   . ARG C 1 427 ? -7.657  52.838  -51.108 1.00 30.74  ? 427 ARG C N   1 
ATOM   10275 C  CA  . ARG C 1 427 ? -6.727  52.677  -52.221 1.00 32.87  ? 427 ARG C CA  1 
ATOM   10276 C  C   . ARG C 1 427 ? -7.225  53.398  -53.472 1.00 27.03  ? 427 ARG C C   1 
ATOM   10277 O  O   . ARG C 1 427 ? -6.438  54.021  -54.184 1.00 28.77  ? 427 ARG C O   1 
ATOM   10278 C  CB  . ARG C 1 427 ? -6.469  51.193  -52.466 1.00 30.24  ? 427 ARG C CB  1 
ATOM   10279 C  CG  . ARG C 1 427 ? -5.420  50.679  -51.462 1.00 33.41  ? 427 ARG C CG  1 
ATOM   10280 C  CD  . ARG C 1 427 ? -5.420  49.199  -51.331 1.00 33.51  ? 427 ARG C CD  1 
ATOM   10281 N  NE  . ARG C 1 427 ? -4.978  48.590  -52.570 1.00 37.29  ? 427 ARG C NE  1 
ATOM   10282 C  CZ  . ARG C 1 427 ? -4.080  47.622  -52.653 1.00 41.50  ? 427 ARG C CZ  1 
ATOM   10283 N  NH1 . ARG C 1 427 ? -3.480  47.146  -51.570 1.00 43.77  ? 427 ARG C NH1 1 
ATOM   10284 N  NH2 . ARG C 1 427 ? -3.787  47.109  -53.852 1.00 37.09  ? 427 ARG C NH2 1 
ATOM   10285 N  N   . GLN C 1 428 ? -8.524  53.368  -53.738 1.00 28.79  ? 428 GLN C N   1 
ATOM   10286 C  CA  . GLN C 1 428 ? -9.033  54.128  -54.873 1.00 30.28  ? 428 GLN C CA  1 
ATOM   10287 C  C   . GLN C 1 428 ? -8.848  55.626  -54.656 1.00 33.62  ? 428 GLN C C   1 
ATOM   10288 O  O   . GLN C 1 428 ? -8.404  56.340  -55.561 1.00 30.92  ? 428 GLN C O   1 
ATOM   10289 C  CB  . GLN C 1 428 ? -10.500 53.798  -55.103 1.00 25.13  ? 428 GLN C CB  1 
ATOM   10290 C  CG  . GLN C 1 428 ? -10.744 52.426  -55.699 1.00 31.60  ? 428 GLN C CG  1 
ATOM   10291 C  CD  . GLN C 1 428 ? -12.215 52.182  -55.941 1.00 33.05  ? 428 GLN C CD  1 
ATOM   10292 O  OE1 . GLN C 1 428 ? -12.866 51.428  -55.221 1.00 30.11  ? 428 GLN C OE1 1 
ATOM   10293 N  NE2 . GLN C 1 428 ? -12.756 52.841  -56.955 1.00 29.61  ? 428 GLN C NE2 1 
ATOM   10294 N  N   . ILE C 1 429 ? -9.166  56.121  -53.452 1.00 30.79  ? 429 ILE C N   1 
ATOM   10295 C  CA  . ILE C 1 429 ? -9.040  57.553  -53.188 1.00 29.92  ? 429 ILE C CA  1 
ATOM   10296 C  C   . ILE C 1 429 ? -7.593  58.002  -53.325 1.00 35.49  ? 429 ILE C C   1 
ATOM   10297 O  O   . ILE C 1 429 ? -7.309  59.065  -53.889 1.00 33.12  ? 429 ILE C O   1 
ATOM   10298 C  CB  . ILE C 1 429 ? -9.607  57.893  -51.804 1.00 31.96  ? 429 ILE C CB  1 
ATOM   10299 C  CG1 . ILE C 1 429 ? -11.131 57.917  -51.882 1.00 28.34  ? 429 ILE C CG1 1 
ATOM   10300 C  CG2 . ILE C 1 429 ? -9.050  59.221  -51.306 1.00 35.40  ? 429 ILE C CG2 1 
ATOM   10301 C  CD1 . ILE C 1 429 ? -11.765 57.557  -50.608 1.00 28.44  ? 429 ILE C CD1 1 
ATOM   10302 N  N   . ALA C 1 430 ? -6.654  57.199  -52.833 1.00 32.24  ? 430 ALA C N   1 
ATOM   10303 C  CA  . ALA C 1 430 ? -5.257  57.592  -52.944 1.00 30.72  ? 430 ALA C CA  1 
ATOM   10304 C  C   . ALA C 1 430 ? -4.788  57.584  -54.402 1.00 35.54  ? 430 ALA C C   1 
ATOM   10305 O  O   . ALA C 1 430 ? -3.900  58.365  -54.781 1.00 30.57  ? 430 ALA C O   1 
ATOM   10306 C  CB  . ALA C 1 430 ? -4.398  56.682  -52.061 1.00 32.53  ? 430 ALA C CB  1 
ATOM   10307 N  N   . ASP C 1 431 ? -5.394  56.744  -55.246 1.00 33.46  ? 431 ASP C N   1 
ATOM   10308 C  CA  . ASP C 1 431 ? -5.061  56.786  -56.666 1.00 29.74  ? 431 ASP C CA  1 
ATOM   10309 C  C   . ASP C 1 431 ? -5.601  58.055  -57.323 1.00 33.61  ? 431 ASP C C   1 
ATOM   10310 O  O   . ASP C 1 431 ? -4.919  58.667  -58.156 1.00 36.08  ? 431 ASP C O   1 
ATOM   10311 C  CB  . ASP C 1 431 ? -5.611  55.547  -57.371 1.00 30.35  ? 431 ASP C CB  1 
ATOM   10312 C  CG  . ASP C 1 431 ? -4.704  54.338  -57.223 1.00 27.47  ? 431 ASP C CG  1 
ATOM   10313 O  OD1 . ASP C 1 431 ? -3.786  54.355  -56.373 1.00 32.06  ? 431 ASP C OD1 1 
ATOM   10314 O  OD2 . ASP C 1 431 ? -4.916  53.362  -57.959 1.00 32.40  ? 431 ASP C OD2 1 
ATOM   10315 N  N   . ARG C 1 432 ? -6.825  58.464  -56.963 1.00 37.39  ? 432 ARG C N   1 
ATOM   10316 C  CA  . ARG C 1 432 ? -7.420  59.688  -57.504 1.00 34.41  ? 432 ARG C CA  1 
ATOM   10317 C  C   . ARG C 1 432 ? -6.800  60.963  -56.938 1.00 40.15  ? 432 ARG C C   1 
ATOM   10318 O  O   . ARG C 1 432 ? -6.924  62.021  -57.566 1.00 38.27  ? 432 ARG C O   1 
ATOM   10319 C  CB  . ARG C 1 432 ? -8.912  59.707  -57.229 1.00 35.23  ? 432 ARG C CB  1 
ATOM   10320 C  CG  . ARG C 1 432 ? -9.709  58.754  -58.060 1.00 37.97  ? 432 ARG C CG  1 
ATOM   10321 C  CD  . ARG C 1 432 ? -11.042 58.643  -57.395 1.00 39.73  ? 432 ARG C CD  1 
ATOM   10322 N  NE  . ARG C 1 432 ? -11.769 57.425  -57.720 1.00 41.15  ? 432 ARG C NE  1 
ATOM   10323 C  CZ  . ARG C 1 432 ? -12.485 56.734  -56.844 1.00 41.74  ? 432 ARG C CZ  1 
ATOM   10324 N  NH1 . ARG C 1 432 ? -12.506 57.057  -55.555 1.00 38.54  ? 432 ARG C NH1 1 
ATOM   10325 N  NH2 . ARG C 1 432 ? -13.203 55.699  -57.268 1.00 45.31  ? 432 ARG C NH2 1 
ATOM   10326 N  N   . LEU C 1 433 ? -6.160  60.902  -55.766 1.00 31.24  ? 433 LEU C N   1 
ATOM   10327 C  CA  . LEU C 1 433 ? -5.437  62.071  -55.274 1.00 35.18  ? 433 LEU C CA  1 
ATOM   10328 C  C   . LEU C 1 433 ? -4.129  62.286  -56.029 1.00 36.54  ? 433 LEU C C   1 
ATOM   10329 O  O   . LEU C 1 433 ? -3.663  63.425  -56.163 1.00 41.08  ? 433 LEU C O   1 
ATOM   10330 C  CB  . LEU C 1 433 ? -5.152  61.933  -53.777 1.00 34.14  ? 433 LEU C CB  1 
ATOM   10331 C  CG  . LEU C 1 433 ? -6.335  62.095  -52.830 1.00 34.61  ? 433 LEU C CG  1 
ATOM   10332 C  CD1 . LEU C 1 433 ? -6.066  61.329  -51.577 1.00 34.71  ? 433 LEU C CD1 1 
ATOM   10333 C  CD2 . LEU C 1 433 ? -6.559  63.539  -52.499 1.00 41.02  ? 433 LEU C CD2 1 
ATOM   10334 N  N   . ALA C 1 434 ? -3.513  61.210  -56.503 1.00 34.91  ? 434 ALA C N   1 
ATOM   10335 C  CA  . ALA C 1 434 ? -2.315  61.353  -57.307 1.00 36.58  ? 434 ALA C CA  1 
ATOM   10336 C  C   . ALA C 1 434 ? -2.635  61.985  -58.653 1.00 43.65  ? 434 ALA C C   1 
ATOM   10337 O  O   . ALA C 1 434 ? -1.766  62.628  -59.256 1.00 41.95  ? 434 ALA C O   1 
ATOM   10338 C  CB  . ALA C 1 434 ? -1.652  59.991  -57.495 1.00 39.66  ? 434 ALA C CB  1 
ATOM   10339 N  N   . GLU C 1 435 ? -3.867  61.806  -59.135 1.00 39.59  ? 435 GLU C N   1 
ATOM   10340 C  CA  . GLU C 1 435 ? -4.380  62.539  -60.295 1.00 44.20  ? 435 GLU C CA  1 
ATOM   10341 C  C   . GLU C 1 435 ? -4.886  63.916  -59.862 1.00 39.60  ? 435 GLU C C   1 
ATOM   10342 O  O   . GLU C 1 435 ? -4.386  64.944  -60.309 1.00 45.68  ? 435 GLU C O   1 
ATOM   10343 C  CB  . GLU C 1 435 ? -5.505  61.748  -60.978 1.00 38.99  ? 435 GLU C CB  1 
ATOM   10344 C  CG  . GLU C 1 435 ? -5.221  60.276  -61.096 1.00 33.35  ? 435 GLU C CG  1 
ATOM   10345 C  CD  . GLU C 1 435 ? -6.448  59.459  -61.511 1.00 42.63  ? 435 GLU C CD  1 
ATOM   10346 O  OE1 . GLU C 1 435 ? -7.576  60.007  -61.552 1.00 40.82  ? 435 GLU C OE1 1 
ATOM   10347 O  OE2 . GLU C 1 435 ? -6.284  58.251  -61.787 1.00 46.94  ? 435 GLU C OE2 1 
ATOM   10348 N  N   . MET D 1 1   ? -9.929  24.868  -29.849 1.00 46.27  ? 1   MET D N   1 
ATOM   10349 C  CA  . MET D 1 1   ? -11.301 25.016  -29.388 1.00 41.87  ? 1   MET D CA  1 
ATOM   10350 C  C   . MET D 1 1   ? -11.836 26.429  -29.535 1.00 42.09  ? 1   MET D C   1 
ATOM   10351 O  O   . MET D 1 1   ? -11.361 27.363  -28.879 1.00 46.10  ? 1   MET D O   1 
ATOM   10352 C  CB  . MET D 1 1   ? -11.439 24.587  -27.923 1.00 36.24  ? 1   MET D CB  1 
ATOM   10353 C  CG  . MET D 1 1   ? -10.949 23.193  -27.643 1.00 40.22  ? 1   MET D CG  1 
ATOM   10354 S  SD  . MET D 1 1   ? -12.230 22.195  -26.874 1.00 45.18  ? 1   MET D SD  1 
ATOM   10355 C  CE  . MET D 1 1   ? -12.638 23.126  -25.392 1.00 36.25  ? 1   MET D CE  1 
ATOM   10356 N  N   . LEU D 1 2   ? -12.854 26.564  -30.376 1.00 34.62  ? 2   LEU D N   1 
ATOM   10357 C  CA  . LEU D 1 2   ? -13.578 27.818  -30.498 1.00 33.44  ? 2   LEU D CA  1 
ATOM   10358 C  C   . LEU D 1 2   ? -14.581 27.989  -29.360 1.00 28.39  ? 2   LEU D C   1 
ATOM   10359 O  O   . LEU D 1 2   ? -15.058 27.022  -28.768 1.00 30.14  ? 2   LEU D O   1 
ATOM   10360 C  CB  . LEU D 1 2   ? -14.297 27.870  -31.846 1.00 29.63  ? 2   LEU D CB  1 
ATOM   10361 C  CG  . LEU D 1 2   ? -13.319 27.790  -33.028 1.00 36.00  ? 2   LEU D CG  1 
ATOM   10362 C  CD1 . LEU D 1 2   ? -13.986 27.235  -34.276 1.00 29.98  ? 2   LEU D CD1 1 
ATOM   10363 C  CD2 . LEU D 1 2   ? -12.733 29.165  -33.306 1.00 26.64  ? 2   LEU D CD2 1 
ATOM   10364 N  N   . LEU D 1 3   ? -14.925 29.244  -29.087 1.00 29.13  ? 3   LEU D N   1 
ATOM   10365 C  CA  . LEU D 1 3   ? -15.924 29.616  -28.094 1.00 27.81  ? 3   LEU D CA  1 
ATOM   10366 C  C   . LEU D 1 3   ? -17.257 29.953  -28.771 1.00 31.02  ? 3   LEU D C   1 
ATOM   10367 O  O   . LEU D 1 3   ? -17.290 30.458  -29.898 1.00 30.07  ? 3   LEU D O   1 
ATOM   10368 C  CB  . LEU D 1 3   ? -15.424 30.815  -27.276 1.00 25.37  ? 3   LEU D CB  1 
ATOM   10369 C  CG  . LEU D 1 3   ? -14.156 30.549  -26.429 1.00 26.01  ? 3   LEU D CG  1 
ATOM   10370 C  CD1 . LEU D 1 3   ? -13.602 31.810  -25.815 1.00 32.16  ? 3   LEU D CD1 1 
ATOM   10371 C  CD2 . LEU D 1 3   ? -14.450 29.534  -25.334 1.00 31.13  ? 3   LEU D CD2 1 
ATOM   10372 N  N   . GLU D 1 4   ? -18.366 29.666  -28.085 1.00 30.27  ? 4   GLU D N   1 
ATOM   10373 C  CA  . GLU D 1 4   ? -19.659 30.064  -28.636 1.00 30.08  ? 4   GLU D CA  1 
ATOM   10374 C  C   . GLU D 1 4   ? -19.784 31.580  -28.576 1.00 27.35  ? 4   GLU D C   1 
ATOM   10375 O  O   . GLU D 1 4   ? -19.084 32.253  -27.825 1.00 27.05  ? 4   GLU D O   1 
ATOM   10376 C  CB  . GLU D 1 4   ? -20.808 29.363  -27.887 1.00 28.57  ? 4   GLU D CB  1 
ATOM   10377 C  CG  . GLU D 1 4   ? -20.521 27.881  -27.660 1.00 32.97  ? 4   GLU D CG  1 
ATOM   10378 C  CD  . GLU D 1 4   ? -21.336 27.238  -26.542 1.00 35.14  ? 4   GLU D CD  1 
ATOM   10379 O  OE1 . GLU D 1 4   ? -22.468 27.695  -26.283 1.00 31.13  ? 4   GLU D OE1 1 
ATOM   10380 O  OE2 . GLU D 1 4   ? -20.854 26.237  -25.963 1.00 30.56  ? 4   GLU D OE2 1 
ATOM   10381 N  N   . ARG D 1 5   ? -20.662 32.139  -29.400 1.00 34.10  ? 5   ARG D N   1 
ATOM   10382 C  CA  . ARG D 1 5   ? -20.659 33.596  -29.466 1.00 27.85  ? 5   ARG D CA  1 
ATOM   10383 C  C   . ARG D 1 5   ? -21.342 34.255  -28.277 1.00 31.38  ? 5   ARG D C   1 
ATOM   10384 O  O   . ARG D 1 5   ? -20.915 35.329  -27.846 1.00 32.95  ? 5   ARG D O   1 
ATOM   10385 C  CB  . ARG D 1 5   ? -21.312 34.082  -30.735 1.00 30.75  ? 5   ARG D CB  1 
ATOM   10386 C  CG  . ARG D 1 5   ? -20.969 35.541  -30.957 1.00 35.88  ? 5   ARG D CG  1 
ATOM   10387 C  CD  . ARG D 1 5   ? -20.378 35.700  -32.285 1.00 34.18  ? 5   ARG D CD  1 
ATOM   10388 N  NE  . ARG D 1 5   ? -19.804 37.017  -32.516 1.00 28.24  ? 5   ARG D NE  1 
ATOM   10389 C  CZ  . ARG D 1 5   ? -19.036 37.289  -33.562 1.00 29.66  ? 5   ARG D CZ  1 
ATOM   10390 N  NH1 . ARG D 1 5   ? -18.633 36.331  -34.390 1.00 31.73  ? 5   ARG D NH1 1 
ATOM   10391 N  NH2 . ARG D 1 5   ? -18.697 38.552  -33.806 1.00 34.68  ? 5   ARG D NH2 1 
ATOM   10392 N  N   . ASP D 1 6   ? -22.434 33.675  -27.778 1.00 33.60  ? 6   ASP D N   1 
ATOM   10393 C  CA  . ASP D 1 6   ? -23.005 34.132  -26.522 1.00 31.93  ? 6   ASP D CA  1 
ATOM   10394 C  C   . ASP D 1 6   ? -21.925 34.115  -25.454 1.00 31.51  ? 6   ASP D C   1 
ATOM   10395 O  O   . ASP D 1 6   ? -21.152 33.161  -25.361 1.00 34.42  ? 6   ASP D O   1 
ATOM   10396 C  CB  . ASP D 1 6   ? -24.163 33.227  -26.090 1.00 32.75  ? 6   ASP D CB  1 
ATOM   10397 C  CG  . ASP D 1 6   ? -25.367 33.326  -27.014 1.00 39.03  ? 6   ASP D CG  1 
ATOM   10398 O  OD1 . ASP D 1 6   ? -25.561 34.397  -27.648 1.00 38.77  ? 6   ASP D OD1 1 
ATOM   10399 O  OD2 . ASP D 1 6   ? -26.100 32.318  -27.118 1.00 33.67  ? 6   ASP D OD2 1 
ATOM   10400 N  N   . LEU D 1 7   ? -21.867 35.182  -24.656 1.00 29.00  ? 7   LEU D N   1 
ATOM   10401 C  CA  . LEU D 1 7   ? -20.863 35.244  -23.601 1.00 29.63  ? 7   LEU D CA  1 
ATOM   10402 C  C   . LEU D 1 7   ? -20.986 34.046  -22.675 1.00 28.24  ? 7   LEU D C   1 
ATOM   10403 O  O   . LEU D 1 7   ? -19.978 33.425  -22.312 1.00 26.85  ? 7   LEU D O   1 
ATOM   10404 C  CB  . LEU D 1 7   ? -20.992 36.544  -22.815 1.00 31.17  ? 7   LEU D CB  1 
ATOM   10405 C  CG  . LEU D 1 7   ? -20.743 37.880  -23.501 1.00 32.53  ? 7   LEU D CG  1 
ATOM   10406 C  CD1 . LEU D 1 7   ? -20.684 38.929  -22.397 1.00 34.73  ? 7   LEU D CD1 1 
ATOM   10407 C  CD2 . LEU D 1 7   ? -19.456 37.879  -24.351 1.00 28.98  ? 7   LEU D CD2 1 
ATOM   10408 N  N   . ILE D 1 8   ? -22.220 33.683  -22.323 1.00 29.80  ? 8   ILE D N   1 
ATOM   10409 C  CA  . ILE D 1 8   ? -22.492 32.498  -21.517 1.00 31.05  ? 8   ILE D CA  1 
ATOM   10410 C  C   . ILE D 1 8   ? -22.474 31.284  -22.432 1.00 30.94  ? 8   ILE D C   1 
ATOM   10411 O  O   . ILE D 1 8   ? -23.295 31.186  -23.348 1.00 33.55  ? 8   ILE D O   1 
ATOM   10412 C  CB  . ILE D 1 8   ? -23.844 32.615  -20.795 1.00 27.40  ? 8   ILE D CB  1 
ATOM   10413 C  CG1 . ILE D 1 8   ? -23.894 33.890  -19.935 1.00 34.03  ? 8   ILE D CG1 1 
ATOM   10414 C  CG2 . ILE D 1 8   ? -24.111 31.359  -19.992 1.00 28.49  ? 8   ILE D CG2 1 
ATOM   10415 C  CD1 . ILE D 1 8   ? -25.304 34.249  -19.451 1.00 36.52  ? 8   ILE D CD1 1 
ATOM   10416 N  N   . GLN D 1 9   ? -21.546 30.357  -22.187 1.00 27.14  ? 9   GLN D N   1 
ATOM   10417 C  CA  . GLN D 1 9   ? -21.483 29.141  -22.996 1.00 28.96  ? 9   GLN D CA  1 
ATOM   10418 C  C   . GLN D 1 9   ? -22.500 28.119  -22.496 1.00 32.45  ? 9   GLN D C   1 
ATOM   10419 O  O   . GLN D 1 9   ? -22.818 28.070  -21.306 1.00 36.72  ? 9   GLN D O   1 
ATOM   10420 C  CB  . GLN D 1 9   ? -20.091 28.517  -22.952 1.00 23.48  ? 9   GLN D CB  1 
ATOM   10421 C  CG  . GLN D 1 9   ? -18.966 29.481  -23.049 1.00 22.19  ? 9   GLN D CG  1 
ATOM   10422 C  CD  . GLN D 1 9   ? -18.848 30.100  -24.433 1.00 30.20  ? 9   GLN D CD  1 
ATOM   10423 O  OE1 . GLN D 1 9   ? -18.481 29.428  -25.406 1.00 27.67  ? 9   GLN D OE1 1 
ATOM   10424 N  NE2 . GLN D 1 9   ? -19.168 31.393  -24.526 1.00 28.88  ? 9   GLN D NE2 1 
ATOM   10425 N  N   . SER D 1 10  ? -23.017 27.300  -23.417 1.00 29.54  ? 10  SER D N   1 
ATOM   10426 C  CA  . SER D 1 10  ? -23.784 26.137  -22.981 1.00 37.05  ? 10  SER D CA  1 
ATOM   10427 C  C   . SER D 1 10  ? -22.877 24.991  -22.572 1.00 35.40  ? 10  SER D C   1 
ATOM   10428 O  O   . SER D 1 10  ? -23.225 24.218  -21.673 1.00 30.15  ? 10  SER D O   1 
ATOM   10429 C  CB  . SER D 1 10  ? -24.743 25.666  -24.069 1.00 30.96  ? 10  SER D CB  1 
ATOM   10430 O  OG  . SER D 1 10  ? -25.551 26.734  -24.516 1.00 36.33  ? 10  SER D OG  1 
ATOM   10431 N  N   . VAL D 1 11  ? -21.713 24.867  -23.189 1.00 30.84  ? 11  VAL D N   1 
ATOM   10432 C  CA  . VAL D 1 11  ? -20.838 23.759  -22.842 1.00 28.01  ? 11  VAL D CA  1 
ATOM   10433 C  C   . VAL D 1 11  ? -20.157 24.061  -21.520 1.00 30.36  ? 11  VAL D C   1 
ATOM   10434 O  O   . VAL D 1 11  ? -19.639 25.168  -21.311 1.00 26.09  ? 11  VAL D O   1 
ATOM   10435 C  CB  . VAL D 1 11  ? -19.827 23.494  -23.959 1.00 33.80  ? 11  VAL D CB  1 
ATOM   10436 C  CG1 . VAL D 1 11  ? -18.591 22.785  -23.379 1.00 25.59  ? 11  VAL D CG1 1 
ATOM   10437 C  CG2 . VAL D 1 11  ? -20.513 22.655  -25.064 1.00 27.60  ? 11  VAL D CG2 1 
ATOM   10438 N  N   . GLY D 1 12  ? -20.170 23.076  -20.617 1.00 29.05  ? 12  GLY D N   1 
ATOM   10439 C  CA  . GLY D 1 12  ? -19.606 23.240  -19.289 1.00 33.40  ? 12  GLY D CA  1 
ATOM   10440 C  C   . GLY D 1 12  ? -20.544 23.789  -18.232 1.00 33.25  ? 12  GLY D C   1 
ATOM   10441 O  O   . GLY D 1 12  ? -20.078 24.162  -17.146 1.00 29.95  ? 12  GLY D O   1 
ATOM   10442 N  N   . PHE D 1 13  ? -21.845 23.861  -18.513 1.00 34.66  ? 13  PHE D N   1 
ATOM   10443 C  CA  . PHE D 1 13  ? -22.859 24.236  -17.522 1.00 30.97  ? 13  PHE D CA  1 
ATOM   10444 C  C   . PHE D 1 13  ? -23.314 22.940  -16.861 1.00 31.48  ? 13  PHE D C   1 
ATOM   10445 O  O   . PHE D 1 13  ? -24.091 22.178  -17.434 1.00 27.51  ? 13  PHE D O   1 
ATOM   10446 C  CB  . PHE D 1 13  ? -23.997 24.989  -18.197 1.00 32.79  ? 13  PHE D CB  1 
ATOM   10447 C  CG  . PHE D 1 13  ? -25.141 25.336  -17.291 1.00 32.78  ? 13  PHE D CG  1 
ATOM   10448 C  CD1 . PHE D 1 13  ? -24.917 25.947  -16.065 1.00 32.85  ? 13  PHE D CD1 1 
ATOM   10449 C  CD2 . PHE D 1 13  ? -26.446 25.092  -17.690 1.00 28.29  ? 13  PHE D CD2 1 
ATOM   10450 C  CE1 . PHE D 1 13  ? -25.981 26.293  -15.244 1.00 36.49  ? 13  PHE D CE1 1 
ATOM   10451 C  CE2 . PHE D 1 13  ? -27.507 25.420  -16.881 1.00 36.94  ? 13  PHE D CE2 1 
ATOM   10452 C  CZ  . PHE D 1 13  ? -27.282 26.032  -15.655 1.00 34.77  ? 13  PHE D CZ  1 
ATOM   10453 N  N   . ARG D 1 14  ? -22.794 22.663  -15.666 1.00 32.94  ? 14  ARG D N   1 
ATOM   10454 C  CA  . ARG D 1 14  ? -23.016 21.372  -15.027 1.00 31.88  ? 14  ARG D CA  1 
ATOM   10455 C  C   . ARG D 1 14  ? -22.950 21.538  -13.516 1.00 34.31  ? 14  ARG D C   1 
ATOM   10456 O  O   . ARG D 1 14  ? -22.369 22.501  -13.002 1.00 30.45  ? 14  ARG D O   1 
ATOM   10457 C  CB  . ARG D 1 14  ? -21.985 20.333  -15.490 1.00 33.32  ? 14  ARG D CB  1 
ATOM   10458 C  CG  . ARG D 1 14  ? -20.588 20.548  -14.894 1.00 32.87  ? 14  ARG D CG  1 
ATOM   10459 C  CD  . ARG D 1 14  ? -19.511 19.780  -15.660 1.00 31.97  ? 14  ARG D CD  1 
ATOM   10460 N  NE  . ARG D 1 14  ? -19.652 18.342  -15.463 1.00 35.43  ? 14  ARG D NE  1 
ATOM   10461 C  CZ  . ARG D 1 14  ? -20.035 17.491  -16.404 1.00 29.69  ? 14  ARG D CZ  1 
ATOM   10462 N  NH1 . ARG D 1 14  ? -20.297 17.895  -17.636 1.00 30.00  ? 14  ARG D NH1 1 
ATOM   10463 N  NH2 . ARG D 1 14  ? -20.172 16.205  -16.097 1.00 35.63  ? 14  ARG D NH2 1 
ATOM   10464 N  N   . ASN D 1 15  ? -23.562 20.587  -12.805 1.00 26.87  ? 15  ASN D N   1 
ATOM   10465 C  CA  . ASN D 1 15  ? -23.381 20.578  -11.366 1.00 35.01  ? 15  ASN D CA  1 
ATOM   10466 C  C   . ASN D 1 15  ? -21.978 20.079  -11.060 1.00 35.72  ? 15  ASN D C   1 
ATOM   10467 O  O   . ASN D 1 15  ? -21.343 19.392  -11.864 1.00 33.86  ? 15  ASN D O   1 
ATOM   10468 C  CB  . ASN D 1 15  ? -24.424 19.701  -10.668 1.00 32.75  ? 15  ASN D CB  1 
ATOM   10469 C  CG  . ASN D 1 15  ? -25.762 20.378  -10.551 1.00 29.03  ? 15  ASN D CG  1 
ATOM   10470 O  OD1 . ASN D 1 15  ? -25.847 21.576  -10.303 1.00 35.31  ? 15  ASN D OD1 1 
ATOM   10471 N  ND2 . ASN D 1 15  ? -26.817 19.620  -10.737 1.00 34.92  ? 15  ASN D ND2 1 
ATOM   10472 N  N   . VAL D 1 16  ? -21.485 20.450  -9.889  1.00 37.62  ? 16  VAL D N   1 
ATOM   10473 C  CA  . VAL D 1 16  ? -20.122 20.143  -9.483  1.00 38.20  ? 16  VAL D CA  1 
ATOM   10474 C  C   . VAL D 1 16  ? -20.209 19.324  -8.208  1.00 38.14  ? 16  VAL D C   1 
ATOM   10475 O  O   . VAL D 1 16  ? -20.962 19.679  -7.297  1.00 35.74  ? 16  VAL D O   1 
ATOM   10476 C  CB  . VAL D 1 16  ? -19.306 21.436  -9.283  1.00 33.66  ? 16  VAL D CB  1 
ATOM   10477 C  CG1 . VAL D 1 16  ? -18.023 21.177  -8.501  1.00 40.23  ? 16  VAL D CG1 1 
ATOM   10478 C  CG2 . VAL D 1 16  ? -19.007 22.070  -10.627 1.00 30.89  ? 16  VAL D CG2 1 
ATOM   10479 N  N   . ARG D 1 17  ? -19.419 18.257  -8.166  1.00 36.23  ? 17  ARG D N   1 
ATOM   10480 C  CA  . ARG D 1 17  ? -19.417 17.365  -6.991  1.00 42.49  ? 17  ARG D CA  1 
ATOM   10481 C  C   . ARG D 1 17  ? -18.001 17.110  -6.483  1.00 45.11  ? 17  ARG D C   1 
ATOM   10482 O  O   . ARG D 1 17  ? -17.062 17.167  -7.285  1.00 38.80  ? 17  ARG D O   1 
ATOM   10483 C  CB  . ARG D 1 17  ? -19.999 15.996  -7.332  1.00 42.88  ? 17  ARG D CB  1 
ATOM   10484 C  CG  . ARG D 1 17  ? -21.298 16.019  -8.121  1.00 45.91  ? 17  ARG D CG  1 
ATOM   10485 C  CD  . ARG D 1 17  ? -21.536 14.663  -8.754  1.00 43.12  ? 17  ARG D CD  1 
ATOM   10486 N  NE  . ARG D 1 17  ? -22.891 14.522  -9.264  1.00 54.08  ? 17  ARG D NE  1 
ATOM   10487 C  CZ  . ARG D 1 17  ? -23.919 14.075  -8.554  1.00 57.69  ? 17  ARG D CZ  1 
ATOM   10488 N  NH1 . ARG D 1 17  ? -23.805 13.927  -7.246  1.00 53.74  ? 17  ARG D NH1 1 
ATOM   10489 N  NH2 . ARG D 1 17  ? -25.060 13.782  -9.153  1.00 56.89  ? 17  ARG D NH2 1 
ATOM   10490 N  N   . GLU D 1 18  ? -17.874 16.874  -5.183  1.00 44.91  ? 18  GLU D N   1 
ATOM   10491 C  CA  . GLU D 1 18  ? -16.584 16.465  -4.586  1.00 43.60  ? 18  GLU D CA  1 
ATOM   10492 C  C   . GLU D 1 18  ? -16.949 15.298  -3.675  1.00 45.53  ? 18  GLU D C   1 
ATOM   10493 O  O   . GLU D 1 18  ? -17.917 15.443  -2.902  1.00 42.61  ? 18  GLU D O   1 
ATOM   10494 C  CB  . GLU D 1 18  ? -15.945 17.609  -3.805  1.00 46.94  ? 18  GLU D CB  1 
ATOM   10495 C  CG  . GLU D 1 18  ? -15.500 18.766  -4.675  1.00 49.64  ? 18  GLU D CG  1 
ATOM   10496 C  CD  . GLU D 1 18  ? -15.435 20.090  -3.939  1.00 55.09  ? 18  GLU D CD  1 
ATOM   10497 O  OE1 . GLU D 1 18  ? -14.923 20.101  -2.806  1.00 56.39  ? 18  GLU D OE1 1 
ATOM   10498 O  OE2 . GLU D 1 18  ? -15.901 21.101  -4.500  1.00 59.69  ? 18  GLU D OE2 1 
ATOM   10499 N  N   . GLY D 1 19  ? -16.292 14.164  -3.853  1.00 39.72  ? 19  GLY D N   1 
ATOM   10500 C  CA  . GLY D 1 19  ? -16.570 12.987  -3.016  1.00 45.27  ? 19  GLY D CA  1 
ATOM   10501 C  C   . GLY D 1 19  ? -17.978 12.448  -3.192  1.00 47.85  ? 19  GLY D C   1 
ATOM   10502 O  O   . GLY D 1 19  ? -18.384 11.621  -2.374  1.00 48.22  ? 19  GLY D O   1 
ATOM   10503 N  N   . GLY D 1 20  ? -18.689 12.888  -4.223  1.00 52.04  ? 20  GLY D N   1 
ATOM   10504 C  CA  . GLY D 1 20  ? -20.029 12.334  -4.517  1.00 57.85  ? 20  GLY D CA  1 
ATOM   10505 C  C   . GLY D 1 20  ? -21.154 13.347  -4.419  1.00 51.26  ? 20  GLY D C   1 
ATOM   10506 O  O   . GLY D 1 20  ? -21.951 13.399  -5.355  1.00 56.61  ? 20  GLY D O   1 
ATOM   10507 N  N   . GLU D 1 21  ? -21.191 14.153  -3.358  1.00 50.90  ? 21  GLU D N   1 
ATOM   10508 C  CA  . GLU D 1 21  ? -22.332 15.082  -3.142  1.00 51.78  ? 21  GLU D CA  1 
ATOM   10509 C  C   . GLU D 1 21  ? -22.155 16.410  -3.895  1.00 52.32  ? 21  GLU D C   1 
ATOM   10510 O  O   . GLU D 1 21  ? -21.022 16.907  -3.949  1.00 48.50  ? 21  GLU D O   1 
ATOM   10511 C  CB  . GLU D 1 21  ? -22.520 15.291  -1.649  1.00 57.68  ? 21  GLU D CB  1 
ATOM   10512 C  CG  . GLU D 1 21  ? -23.961 15.548  -1.256  1.00 65.72  ? 21  GLU D CG  1 
ATOM   10513 C  CD  . GLU D 1 21  ? -24.662 14.340  -0.662  1.00 65.05  ? 21  GLU D CD  1 
ATOM   10514 O  OE1 . GLU D 1 21  ? -24.276 13.927  0.445   1.00 68.24  ? 21  GLU D OE1 1 
ATOM   10515 O  OE2 . GLU D 1 21  ? -25.584 13.815  -1.313  1.00 68.21  ? 21  GLU D OE2 1 
ATOM   10516 N  N   . ILE D 1 22  ? -23.252 16.964  -4.429  1.00 48.61  ? 22  ILE D N   1 
ATOM   10517 C  CA  . ILE D 1 22  ? -23.178 18.205  -5.259  1.00 42.77  ? 22  ILE D CA  1 
ATOM   10518 C  C   . ILE D 1 22  ? -22.909 19.425  -4.381  1.00 41.74  ? 22  ILE D C   1 
ATOM   10519 O  O   . ILE D 1 22  ? -23.741 19.740  -3.527  1.00 35.70  ? 22  ILE D O   1 
ATOM   10520 C  CB  . ILE D 1 22  ? -24.404 18.390  -6.179  1.00 42.00  ? 22  ILE D CB  1 
ATOM   10521 C  CG1 . ILE D 1 22  ? -24.623 17.163  -7.065  1.00 39.83  ? 22  ILE D CG1 1 
ATOM   10522 C  CG2 . ILE D 1 22  ? -24.266 19.655  -7.004  1.00 36.13  ? 22  ILE D CG2 1 
ATOM   10523 C  CD1 . ILE D 1 22  ? -25.977 17.109  -7.716  1.00 40.34  ? 22  ILE D CD1 1 
ATOM   10524 N  N   . THR D 1 23  ? -21.774 20.073  -4.623  1.00 40.09  ? 23  THR D N   1 
ATOM   10525 C  CA  . THR D 1 23  ? -21.373 21.270  -3.910  1.00 40.12  ? 23  THR D CA  1 
ATOM   10526 C  C   . THR D 1 23  ? -21.886 22.549  -4.559  1.00 36.68  ? 23  THR D C   1 
ATOM   10527 O  O   . THR D 1 23  ? -21.983 23.572  -3.877  1.00 34.67  ? 23  THR D O   1 
ATOM   10528 C  CB  . THR D 1 23  ? -19.848 21.296  -3.826  1.00 44.50  ? 23  THR D CB  1 
ATOM   10529 O  OG1 . THR D 1 23  ? -19.314 21.737  -5.079  1.00 41.93  ? 23  THR D OG1 1 
ATOM   10530 C  CG2 . THR D 1 23  ? -19.326 19.889  -3.568  1.00 43.42  ? 23  THR D CG2 1 
ATOM   10531 N  N   . GLY D 1 24  ? -22.220 22.507  -5.849  1.00 37.37  ? 24  GLY D N   1 
ATOM   10532 C  CA  . GLY D 1 24  ? -22.784 23.656  -6.544  1.00 29.47  ? 24  GLY D CA  1 
ATOM   10533 C  C   . GLY D 1 24  ? -22.805 23.427  -8.047  1.00 33.79  ? 24  GLY D C   1 
ATOM   10534 O  O   . GLY D 1 24  ? -22.845 22.289  -8.514  1.00 34.50  ? 24  GLY D O   1 
ATOM   10535 N  N   . PHE D 1 25  ? -22.744 24.522  -8.799  1.00 30.52  ? 25  PHE D N   1 
ATOM   10536 C  CA  . PHE D 1 25  ? -22.704 24.388  -10.247 1.00 27.54  ? 25  PHE D CA  1 
ATOM   10537 C  C   . PHE D 1 25  ? -21.727 25.400  -10.844 1.00 29.06  ? 25  PHE D C   1 
ATOM   10538 O  O   . PHE D 1 25  ? -21.280 26.350  -10.188 1.00 26.41  ? 25  PHE D O   1 
ATOM   10539 C  CB  . PHE D 1 25  ? -24.102 24.534  -10.853 1.00 24.30  ? 25  PHE D CB  1 
ATOM   10540 C  CG  . PHE D 1 25  ? -24.612 25.914  -10.849 1.00 30.81  ? 25  PHE D CG  1 
ATOM   10541 C  CD1 . PHE D 1 25  ? -25.185 26.445  -9.714  1.00 31.06  ? 25  PHE D CD1 1 
ATOM   10542 C  CD2 . PHE D 1 25  ? -24.514 26.702  -11.986 1.00 30.15  ? 25  PHE D CD2 1 
ATOM   10543 C  CE1 . PHE D 1 25  ? -25.660 27.733  -9.702  1.00 30.72  ? 25  PHE D CE1 1 
ATOM   10544 C  CE2 . PHE D 1 25  ? -24.978 27.982  -11.981 1.00 28.91  ? 25  PHE D CE2 1 
ATOM   10545 C  CZ  . PHE D 1 25  ? -25.558 28.509  -10.836 1.00 38.32  ? 25  PHE D CZ  1 
ATOM   10546 N  N   . GLN D 1 26  ? -21.377 25.156  -12.101 1.00 28.83  ? 26  GLN D N   1 
ATOM   10547 C  CA  . GLN D 1 26  ? -20.409 25.972  -12.811 1.00 28.18  ? 26  GLN D CA  1 
ATOM   10548 C  C   . GLN D 1 26  ? -20.969 26.340  -14.176 1.00 29.79  ? 26  GLN D C   1 
ATOM   10549 O  O   . GLN D 1 26  ? -21.948 25.752  -14.652 1.00 27.01  ? 26  GLN D O   1 
ATOM   10550 C  CB  . GLN D 1 26  ? -19.061 25.248  -12.964 1.00 23.78  ? 26  GLN D CB  1 
ATOM   10551 C  CG  . GLN D 1 26  ? -19.148 23.944  -13.727 1.00 25.57  ? 26  GLN D CG  1 
ATOM   10552 C  CD  . GLN D 1 26  ? -17.818 23.524  -14.303 1.00 32.22  ? 26  GLN D CD  1 
ATOM   10553 O  OE1 . GLN D 1 26  ? -16.775 23.646  -13.653 1.00 29.86  ? 26  GLN D OE1 1 
ATOM   10554 N  NE2 . GLN D 1 26  ? -17.844 23.007  -15.535 1.00 29.43  ? 26  GLN D NE2 1 
ATOM   10555 N  N   . PHE D 1 27  ? -20.349 27.343  -14.792 1.00 28.13  ? 27  PHE D N   1 
ATOM   10556 C  CA  . PHE D 1 27  ? -20.640 27.685  -16.178 1.00 29.47  ? 27  PHE D CA  1 
ATOM   10557 C  C   . PHE D 1 27  ? -19.451 28.468  -16.706 1.00 26.66  ? 27  PHE D C   1 
ATOM   10558 O  O   . PHE D 1 27  ? -18.546 28.830  -15.959 1.00 27.24  ? 27  PHE D O   1 
ATOM   10559 C  CB  . PHE D 1 27  ? -21.957 28.463  -16.334 1.00 26.09  ? 27  PHE D CB  1 
ATOM   10560 C  CG  . PHE D 1 27  ? -21.920 29.855  -15.783 1.00 24.26  ? 27  PHE D CG  1 
ATOM   10561 C  CD1 . PHE D 1 27  ? -22.238 30.100  -14.459 1.00 28.11  ? 27  PHE D CD1 1 
ATOM   10562 C  CD2 . PHE D 1 27  ? -21.569 30.922  -16.588 1.00 23.86  ? 27  PHE D CD2 1 
ATOM   10563 C  CE1 . PHE D 1 27  ? -22.199 31.377  -13.944 1.00 30.01  ? 27  PHE D CE1 1 
ATOM   10564 C  CE2 . PHE D 1 27  ? -21.534 32.202  -16.084 1.00 25.50  ? 27  PHE D CE2 1 
ATOM   10565 C  CZ  . PHE D 1 27  ? -21.846 32.435  -14.757 1.00 29.92  ? 27  PHE D CZ  1 
ATOM   10566 N  N   . ARG D 1 28  ? -19.443 28.702  -18.010 1.00 28.22  ? 28  ARG D N   1 
ATOM   10567 C  CA  . ARG D 1 28  ? -18.256 29.233  -18.653 1.00 23.69  ? 28  ARG D CA  1 
ATOM   10568 C  C   . ARG D 1 28  ? -18.606 30.526  -19.369 1.00 27.11  ? 28  ARG D C   1 
ATOM   10569 O  O   . ARG D 1 28  ? -19.728 30.699  -19.848 1.00 29.43  ? 28  ARG D O   1 
ATOM   10570 C  CB  . ARG D 1 28  ? -17.647 28.199  -19.620 1.00 26.32  ? 28  ARG D CB  1 
ATOM   10571 C  CG  . ARG D 1 28  ? -16.863 27.123  -18.869 1.00 25.92  ? 28  ARG D CG  1 
ATOM   10572 C  CD  . ARG D 1 28  ? -16.505 25.960  -19.728 1.00 26.87  ? 28  ARG D CD  1 
ATOM   10573 N  NE  . ARG D 1 28  ? -15.606 26.390  -20.791 1.00 30.85  ? 28  ARG D NE  1 
ATOM   10574 C  CZ  . ARG D 1 28  ? -15.946 26.426  -22.073 1.00 32.14  ? 28  ARG D CZ  1 
ATOM   10575 N  NH1 . ARG D 1 28  ? -17.161 26.070  -22.475 1.00 24.78  ? 28  ARG D NH1 1 
ATOM   10576 N  NH2 . ARG D 1 28  ? -15.055 26.852  -22.972 1.00 31.60  ? 28  ARG D NH2 1 
ATOM   10577 N  N   . VAL D 1 29  ? -17.641 31.443  -19.397 1.00 23.08  ? 29  VAL D N   1 
ATOM   10578 C  CA  . VAL D 1 29  ? -17.832 32.784  -19.930 1.00 29.22  ? 29  VAL D CA  1 
ATOM   10579 C  C   . VAL D 1 29  ? -16.637 33.109  -20.809 1.00 26.55  ? 29  VAL D C   1 
ATOM   10580 O  O   . VAL D 1 29  ? -15.489 32.953  -20.384 1.00 29.18  ? 29  VAL D O   1 
ATOM   10581 C  CB  . VAL D 1 29  ? -17.948 33.846  -18.817 1.00 27.31  ? 29  VAL D CB  1 
ATOM   10582 C  CG1 . VAL D 1 29  ? -18.144 35.262  -19.432 1.00 23.98  ? 29  VAL D CG1 1 
ATOM   10583 C  CG2 . VAL D 1 29  ? -19.048 33.493  -17.841 1.00 28.42  ? 29  VAL D CG2 1 
ATOM   10584 N  N   . ARG D 1 30  ? -16.892 33.590  -22.015 1.00 33.04  ? 30  ARG D N   1 
ATOM   10585 C  CA  . ARG D 1 30  ? -15.794 34.100  -22.816 1.00 30.97  ? 30  ARG D CA  1 
ATOM   10586 C  C   . ARG D 1 30  ? -15.595 35.577  -22.509 1.00 24.68  ? 30  ARG D C   1 
ATOM   10587 O  O   . ARG D 1 30  ? -16.563 36.309  -22.310 1.00 26.49  ? 30  ARG D O   1 
ATOM   10588 C  CB  . ARG D 1 30  ? -16.046 33.883  -24.308 1.00 36.76  ? 30  ARG D CB  1 
ATOM   10589 C  CG  . ARG D 1 30  ? -17.479 34.054  -24.762 1.00 37.50  ? 30  ARG D CG  1 
ATOM   10590 C  CD  . ARG D 1 30  ? -17.546 34.050  -26.307 1.00 42.56  ? 30  ARG D CD  1 
ATOM   10591 N  NE  . ARG D 1 30  ? -16.803 35.126  -26.942 1.00 33.88  ? 30  ARG D NE  1 
ATOM   10592 C  CZ  . ARG D 1 30  ? -17.287 36.318  -27.276 1.00 35.47  ? 30  ARG D CZ  1 
ATOM   10593 N  NH1 . ARG D 1 30  ? -18.590 36.565  -27.311 1.00 36.27  ? 30  ARG D NH1 1 
ATOM   10594 N  NH2 . ARG D 1 30  ? -16.438 37.283  -27.601 1.00 28.56  ? 30  ARG D NH2 1 
ATOM   10595 N  N   . MET D 1 31  ? -14.327 35.986  -22.432 1.00 27.02  ? 31  MET D N   1 
ATOM   10596 C  CA  . MET D 1 31  ? -13.903 37.376  -22.302 1.00 33.70  ? 31  MET D CA  1 
ATOM   10597 C  C   . MET D 1 31  ? -14.671 38.285  -23.264 1.00 34.05  ? 31  MET D C   1 
ATOM   10598 O  O   . MET D 1 31  ? -14.614 38.069  -24.486 1.00 36.19  ? 31  MET D O   1 
ATOM   10599 C  CB  . MET D 1 31  ? -12.400 37.476  -22.572 1.00 30.20  ? 31  MET D CB  1 
ATOM   10600 C  CG  . MET D 1 31  ? -11.809 38.823  -22.351 1.00 30.57  ? 31  MET D CG  1 
ATOM   10601 S  SD  . MET D 1 31  ? -12.427 39.632  -20.865 1.00 33.99  ? 31  MET D SD  1 
ATOM   10602 C  CE  . MET D 1 31  ? -10.912 39.671  -19.903 1.00 29.99  ? 31  MET D CE  1 
ATOM   10603 N  N   . PRO D 1 32  ? -15.403 39.310  -22.756 1.00 31.39  ? 32  PRO D N   1 
ATOM   10604 C  CA  . PRO D 1 32  ? -16.167 40.195  -23.652 1.00 31.64  ? 32  PRO D CA  1 
ATOM   10605 C  C   . PRO D 1 32  ? -15.261 41.232  -24.286 1.00 31.06  ? 32  PRO D C   1 
ATOM   10606 O  O   . PRO D 1 32  ? -15.519 41.735  -25.382 1.00 31.72  ? 32  PRO D O   1 
ATOM   10607 C  CB  . PRO D 1 32  ? -17.196 40.837  -22.716 1.00 34.05  ? 32  PRO D CB  1 
ATOM   10608 C  CG  . PRO D 1 32  ? -16.527 40.794  -21.354 1.00 27.06  ? 32  PRO D CG  1 
ATOM   10609 C  CD  . PRO D 1 32  ? -15.751 39.522  -21.337 1.00 35.19  ? 32  PRO D CD  1 
ATOM   10610 N  N   . SER D 1 33  ? -14.174 41.523  -23.583 1.00 28.65  ? 33  SER D N   1 
ATOM   10611 C  CA  . SER D 1 33  ? -13.175 42.468  -24.012 1.00 29.95  ? 33  SER D CA  1 
ATOM   10612 C  C   . SER D 1 33  ? -12.438 41.952  -25.240 1.00 28.94  ? 33  SER D C   1 
ATOM   10613 O  O   . SER D 1 33  ? -12.496 40.771  -25.609 1.00 31.60  ? 33  SER D O   1 
ATOM   10614 C  CB  . SER D 1 33  ? -12.196 42.732  -22.874 1.00 26.72  ? 33  SER D CB  1 
ATOM   10615 O  OG  . SER D 1 33  ? -11.170 43.606  -23.259 1.00 29.27  ? 33  SER D OG  1 
ATOM   10616 N  N   . TYR D 1 34  ? -11.715 42.859  -25.865 1.00 32.79  ? 34  TYR D N   1 
ATOM   10617 C  CA  . TYR D 1 34  ? -10.926 42.519  -27.032 1.00 32.56  ? 34  TYR D CA  1 
ATOM   10618 C  C   . TYR D 1 34  ? -9.549  41.992  -26.673 1.00 34.83  ? 34  TYR D C   1 
ATOM   10619 O  O   . TYR D 1 34  ? -8.767  41.727  -27.583 1.00 29.09  ? 34  TYR D O   1 
ATOM   10620 C  CB  . TYR D 1 34  ? -10.797 43.734  -27.954 1.00 30.07  ? 34  TYR D CB  1 
ATOM   10621 C  CG  . TYR D 1 34  ? -10.578 45.031  -27.233 1.00 36.16  ? 34  TYR D CG  1 
ATOM   10622 C  CD1 . TYR D 1 34  ? -11.542 46.035  -27.277 1.00 39.92  ? 34  TYR D CD1 1 
ATOM   10623 C  CD2 . TYR D 1 34  ? -9.398  45.276  -26.537 1.00 36.25  ? 34  TYR D CD2 1 
ATOM   10624 C  CE1 . TYR D 1 34  ? -11.346 47.229  -26.634 1.00 33.35  ? 34  TYR D CE1 1 
ATOM   10625 C  CE2 . TYR D 1 34  ? -9.186  46.478  -25.902 1.00 31.97  ? 34  TYR D CE2 1 
ATOM   10626 C  CZ  . TYR D 1 34  ? -10.170 47.445  -25.956 1.00 40.03  ? 34  TYR D CZ  1 
ATOM   10627 O  OH  . TYR D 1 34  ? -9.992  48.637  -25.319 1.00 48.48  ? 34  TYR D OH  1 
ATOM   10628 N  N   . ARG D 1 35  ? -9.233  41.848  -25.379 1.00 27.97  ? 35  ARG D N   1 
ATOM   10629 C  CA  . ARG D 1 35  ? -7.996  41.227  -24.936 1.00 22.22  ? 35  ARG D CA  1 
ATOM   10630 C  C   . ARG D 1 35  ? -8.252  40.409  -23.674 1.00 30.55  ? 35  ARG D C   1 
ATOM   10631 O  O   . ARG D 1 35  ? -9.105  40.754  -22.850 1.00 33.48  ? 35  ARG D O   1 
ATOM   10632 C  CB  . ARG D 1 35  ? -6.917  42.258  -24.643 1.00 26.14  ? 35  ARG D CB  1 
ATOM   10633 C  CG  . ARG D 1 35  ? -7.370  43.280  -23.666 1.00 25.56  ? 35  ARG D CG  1 
ATOM   10634 C  CD  . ARG D 1 35  ? -6.233  43.805  -22.877 1.00 24.15  ? 35  ARG D CD  1 
ATOM   10635 N  NE  . ARG D 1 35  ? -6.731  44.869  -22.028 1.00 22.62  ? 35  ARG D NE  1 
ATOM   10636 C  CZ  . ARG D 1 35  ? -6.076  45.368  -20.994 1.00 25.88  ? 35  ARG D CZ  1 
ATOM   10637 N  NH1 . ARG D 1 35  ? -4.866  44.945  -20.679 1.00 29.31  ? 35  ARG D NH1 1 
ATOM   10638 N  NH2 . ARG D 1 35  ? -6.640  46.336  -20.271 1.00 30.29  ? 35  ARG D NH2 1 
ATOM   10639 N  N   . GLY D 1 36  ? -7.501  39.324  -23.527 1.00 26.80  ? 36  GLY D N   1 
ATOM   10640 C  CA  . GLY D 1 36  ? -7.340  38.744  -22.211 1.00 29.21  ? 36  GLY D CA  1 
ATOM   10641 C  C   . GLY D 1 36  ? -6.660  39.728  -21.288 1.00 27.49  ? 36  GLY D C   1 
ATOM   10642 O  O   . GLY D 1 36  ? -6.006  40.669  -21.736 1.00 25.50  ? 36  GLY D O   1 
ATOM   10643 N  N   . MET D 1 37  ? -6.822  39.522  -19.984 1.00 28.78  ? 37  MET D N   1 
ATOM   10644 C  CA  . MET D 1 37  ? -6.377  40.514  -19.013 1.00 25.14  ? 37  MET D CA  1 
ATOM   10645 C  C   . MET D 1 37  ? -5.828  39.829  -17.773 1.00 27.36  ? 37  MET D C   1 
ATOM   10646 O  O   . MET D 1 37  ? -6.094  38.646  -17.525 1.00 28.23  ? 37  MET D O   1 
ATOM   10647 C  CB  . MET D 1 37  ? -7.515  41.464  -18.605 1.00 29.60  ? 37  MET D CB  1 
ATOM   10648 C  CG  . MET D 1 37  ? -8.110  42.264  -19.779 1.00 37.90  ? 37  MET D CG  1 
ATOM   10649 S  SD  . MET D 1 37  ? -9.702  43.040  -19.418 1.00 46.64  ? 37  MET D SD  1 
ATOM   10650 C  CE  . MET D 1 37  ? -9.491  43.337  -17.695 1.00 25.63  ? 37  MET D CE  1 
ATOM   10651 N  N   . ALA D 1 38  ? -5.045  40.599  -17.004 1.00 29.48  ? 38  ALA D N   1 
ATOM   10652 C  CA  . ALA D 1 38  ? -4.615  40.155  -15.683 1.00 27.27  ? 38  ALA D CA  1 
ATOM   10653 C  C   . ALA D 1 38  ? -5.855  39.849  -14.861 1.00 28.09  ? 38  ALA D C   1 
ATOM   10654 O  O   . ALA D 1 38  ? -6.854  40.557  -14.952 1.00 29.57  ? 38  ALA D O   1 
ATOM   10655 C  CB  . ALA D 1 38  ? -3.767  41.231  -15.003 1.00 25.45  ? 38  ALA D CB  1 
ATOM   10656 N  N   . ALA D 1 39  ? -5.824  38.749  -14.107 1.00 29.35  ? 39  ALA D N   1 
ATOM   10657 C  CA  . ALA D 1 39  ? -7.013  38.380  -13.343 1.00 26.65  ? 39  ALA D CA  1 
ATOM   10658 C  C   . ALA D 1 39  ? -7.364  39.415  -12.267 1.00 22.36  ? 39  ALA D C   1 
ATOM   10659 O  O   . ALA D 1 39  ? -8.535  39.565  -11.924 1.00 25.91  ? 39  ALA D O   1 
ATOM   10660 C  CB  . ALA D 1 39  ? -6.819  36.993  -12.733 1.00 26.31  ? 39  ALA D CB  1 
ATOM   10661 N  N   . SER D 1 40  ? -6.401  40.178  -11.776 1.00 24.75  ? 40  SER D N   1 
ATOM   10662 C  CA  . SER D 1 40  ? -6.716  41.128  -10.718 1.00 21.53  ? 40  SER D CA  1 
ATOM   10663 C  C   . SER D 1 40  ? -7.629  42.258  -11.169 1.00 29.70  ? 40  SER D C   1 
ATOM   10664 O  O   . SER D 1 40  ? -8.145  42.969  -10.306 1.00 27.16  ? 40  SER D O   1 
ATOM   10665 C  CB  . SER D 1 40  ? -5.436  41.708  -10.143 1.00 29.10  ? 40  SER D CB  1 
ATOM   10666 O  OG  . SER D 1 40  ? -4.818  42.571  -11.072 1.00 27.11  ? 40  SER D OG  1 
ATOM   10667 N  N   . LEU D 1 41  ? -7.845  42.439  -12.483 1.00 29.05  ? 41  LEU D N   1 
ATOM   10668 C  CA  . LEU D 1 41  ? -8.723  43.477  -13.011 1.00 25.28  ? 41  LEU D CA  1 
ATOM   10669 C  C   . LEU D 1 41  ? -10.177 43.044  -13.117 1.00 27.67  ? 41  LEU D C   1 
ATOM   10670 O  O   . LEU D 1 41  ? -11.030 43.866  -13.475 1.00 28.72  ? 41  LEU D O   1 
ATOM   10671 C  CB  . LEU D 1 41  ? -8.238  43.933  -14.402 1.00 27.17  ? 41  LEU D CB  1 
ATOM   10672 C  CG  . LEU D 1 41  ? -6.853  44.549  -14.511 1.00 24.43  ? 41  LEU D CG  1 
ATOM   10673 C  CD1 . LEU D 1 41  ? -6.396  44.563  -15.970 1.00 24.16  ? 41  LEU D CD1 1 
ATOM   10674 C  CD2 . LEU D 1 41  ? -6.841  45.960  -13.906 1.00 30.25  ? 41  LEU D CD2 1 
ATOM   10675 N  N   . ILE D 1 42  ? -10.478 41.775  -12.855 1.00 29.51  ? 42  ILE D N   1 
ATOM   10676 C  CA  . ILE D 1 42  ? -11.864 41.350  -12.739 1.00 27.34  ? 42  ILE D CA  1 
ATOM   10677 C  C   . ILE D 1 42  ? -12.478 41.981  -11.497 1.00 36.84  ? 42  ILE D C   1 
ATOM   10678 O  O   . ILE D 1 42  ? -11.839 42.067  -10.442 1.00 33.01  ? 42  ILE D O   1 
ATOM   10679 C  CB  . ILE D 1 42  ? -11.946 39.819  -12.677 1.00 30.26  ? 42  ILE D CB  1 
ATOM   10680 C  CG1 . ILE D 1 42  ? -11.362 39.212  -13.961 1.00 28.23  ? 42  ILE D CG1 1 
ATOM   10681 C  CG2 . ILE D 1 42  ? -13.376 39.394  -12.490 1.00 29.94  ? 42  ILE D CG2 1 
ATOM   10682 C  CD1 . ILE D 1 42  ? -11.164 37.695  -13.919 1.00 22.82  ? 42  ILE D CD1 1 
ATOM   10683 N  N   . ASP D 1 43  ? -13.717 42.453  -11.622 1.00 35.39  ? 43  ASP D N   1 
ATOM   10684 C  CA  . ASP D 1 43  ? -14.439 43.036  -10.501 1.00 35.33  ? 43  ASP D CA  1 
ATOM   10685 C  C   . ASP D 1 43  ? -15.638 42.182  -10.113 1.00 38.01  ? 43  ASP D C   1 
ATOM   10686 O  O   . ASP D 1 43  ? -16.514 42.634  -9.374  1.00 33.16  ? 43  ASP D O   1 
ATOM   10687 C  CB  . ASP D 1 43  ? -14.871 44.466  -10.822 1.00 33.94  ? 43  ASP D CB  1 
ATOM   10688 C  CG  . ASP D 1 43  ? -14.089 45.505  -10.053 1.00 38.41  ? 43  ASP D CG  1 
ATOM   10689 O  OD1 . ASP D 1 43  ? -13.009 45.192  -9.497  1.00 42.02  ? 43  ASP D OD1 1 
ATOM   10690 O  OD2 . ASP D 1 43  ? -14.556 46.660  -10.015 1.00 42.01  ? 43  ASP D OD2 1 
ATOM   10691 N  N   . GLY D 1 44  ? -15.686 40.952  -10.595 1.00 34.37  ? 44  GLY D N   1 
ATOM   10692 C  CA  . GLY D 1 44  ? -16.659 39.996  -10.125 1.00 32.76  ? 44  GLY D CA  1 
ATOM   10693 C  C   . GLY D 1 44  ? -17.750 39.793  -11.140 1.00 34.56  ? 44  GLY D C   1 
ATOM   10694 O  O   . GLY D 1 44  ? -17.800 40.434  -12.194 1.00 34.25  ? 44  GLY D O   1 
ATOM   10695 N  N   . ILE D 1 45  ? -18.650 38.879  -10.789 1.00 30.56  ? 45  ILE D N   1 
ATOM   10696 C  CA  . ILE D 1 45  ? -19.744 38.483  -11.660 1.00 33.73  ? 45  ILE D CA  1 
ATOM   10697 C  C   . ILE D 1 45  ? -20.954 38.191  -10.781 1.00 36.23  ? 45  ILE D C   1 
ATOM   10698 O  O   . ILE D 1 45  ? -20.914 37.322  -9.906  1.00 37.51  ? 45  ILE D O   1 
ATOM   10699 C  CB  . ILE D 1 45  ? -19.344 37.270  -12.541 1.00 31.57  ? 45  ILE D CB  1 
ATOM   10700 C  CG1 . ILE D 1 45  ? -20.497 36.818  -13.442 1.00 34.15  ? 45  ILE D CG1 1 
ATOM   10701 C  CG2 . ILE D 1 45  ? -18.839 36.099  -11.699 1.00 30.94  ? 45  ILE D CG2 1 
ATOM   10702 C  CD1 . ILE D 1 45  ? -20.079 35.895  -14.609 1.00 24.15  ? 45  ILE D CD1 1 
ATOM   10703 N  N   . GLY D 1 46  ? -22.031 38.942  -10.972 1.00 39.33  ? 46  GLY D N   1 
ATOM   10704 C  CA  . GLY D 1 46  ? -23.287 38.565  -10.364 1.00 36.73  ? 46  GLY D CA  1 
ATOM   10705 C  C   . GLY D 1 46  ? -23.914 37.437  -11.161 1.00 37.77  ? 46  GLY D C   1 
ATOM   10706 O  O   . GLY D 1 46  ? -23.809 37.380  -12.385 1.00 37.69  ? 46  GLY D O   1 
ATOM   10707 N  N   . VAL D 1 47  ? -24.551 36.515  -10.455 1.00 33.62  ? 47  VAL D N   1 
ATOM   10708 C  CA  . VAL D 1 47  ? -25.206 35.400  -11.116 1.00 36.56  ? 47  VAL D CA  1 
ATOM   10709 C  C   . VAL D 1 47  ? -26.609 35.264  -10.546 1.00 45.81  ? 47  VAL D C   1 
ATOM   10710 O  O   . VAL D 1 47  ? -26.854 35.550  -9.367  1.00 36.14  ? 47  VAL D O   1 
ATOM   10711 C  CB  . VAL D 1 47  ? -24.414 34.080  -10.964 1.00 37.41  ? 47  VAL D CB  1 
ATOM   10712 C  CG1 . VAL D 1 47  ? -25.060 32.998  -11.778 1.00 35.71  ? 47  VAL D CG1 1 
ATOM   10713 C  CG2 . VAL D 1 47  ? -22.961 34.257  -11.408 1.00 32.45  ? 47  VAL D CG2 1 
ATOM   10714 N  N   . ARG D 1 48  ? -27.538 34.837  -11.404 1.00 38.76  ? 48  ARG D N   1 
ATOM   10715 C  CA  . ARG D 1 48  ? -28.917 34.659  -10.983 1.00 40.89  ? 48  ARG D CA  1 
ATOM   10716 C  C   . ARG D 1 48  ? -29.651 33.770  -11.974 1.00 43.54  ? 48  ARG D C   1 
ATOM   10717 O  O   . ARG D 1 48  ? -29.605 34.018  -13.182 1.00 45.92  ? 48  ARG D O   1 
ATOM   10718 C  CB  . ARG D 1 48  ? -29.631 36.004  -10.857 1.00 41.24  ? 48  ARG D CB  1 
ATOM   10719 C  CG  . ARG D 1 48  ? -31.013 35.875  -10.274 1.00 49.52  ? 48  ARG D CG  1 
ATOM   10720 C  CD  . ARG D 1 48  ? -31.835 37.145  -10.427 1.00 58.58  ? 48  ARG D CD  1 
ATOM   10721 N  NE  . ARG D 1 48  ? -33.248 36.818  -10.599 1.00 61.88  ? 48  ARG D NE  1 
ATOM   10722 C  CZ  . ARG D 1 48  ? -34.098 36.630  -9.596  1.00 63.18  ? 48  ARG D CZ  1 
ATOM   10723 N  NH1 . ARG D 1 48  ? -33.705 36.709  -8.330  1.00 59.27  ? 48  ARG D NH1 1 
ATOM   10724 N  NH2 . ARG D 1 48  ? -35.371 36.348  -9.867  1.00 63.61  ? 48  ARG D NH2 1 
ATOM   10725 N  N   . ILE D 1 49  ? -30.287 32.725  -11.459 1.00 44.38  ? 49  ILE D N   1 
ATOM   10726 C  CA  . ILE D 1 49  ? -31.376 32.007  -12.118 1.00 44.62  ? 49  ILE D CA  1 
ATOM   10727 C  C   . ILE D 1 49  ? -32.626 32.255  -11.281 1.00 47.31  ? 49  ILE D C   1 
ATOM   10728 O  O   . ILE D 1 49  ? -32.627 31.941  -10.081 1.00 47.60  ? 49  ILE D O   1 
ATOM   10729 C  CB  . ILE D 1 49  ? -31.099 30.498  -12.256 1.00 43.64  ? 49  ILE D CB  1 
ATOM   10730 C  CG1 . ILE D 1 49  ? -29.841 30.239  -13.076 1.00 45.09  ? 49  ILE D CG1 1 
ATOM   10731 C  CG2 . ILE D 1 49  ? -32.236 29.819  -12.965 1.00 40.93  ? 49  ILE D CG2 1 
ATOM   10732 C  CD1 . ILE D 1 49  ? -28.965 29.155  -12.529 1.00 39.78  ? 49  ILE D CD1 1 
ATOM   10733 N  N   . PRO D 1 50  ? -33.680 32.843  -11.847 1.00 47.95  ? 50  PRO D N   1 
ATOM   10734 C  CA  . PRO D 1 50  ? -34.848 33.227  -11.037 1.00 50.10  ? 50  PRO D CA  1 
ATOM   10735 C  C   . PRO D 1 50  ? -35.425 32.050  -10.266 1.00 47.99  ? 50  PRO D C   1 
ATOM   10736 O  O   . PRO D 1 50  ? -35.669 30.977  -10.820 1.00 47.65  ? 50  PRO D O   1 
ATOM   10737 C  CB  . PRO D 1 50  ? -35.846 33.767  -12.069 1.00 54.24  ? 50  PRO D CB  1 
ATOM   10738 C  CG  . PRO D 1 50  ? -35.070 34.012  -13.325 1.00 56.83  ? 50  PRO D CG  1 
ATOM   10739 C  CD  . PRO D 1 50  ? -33.727 33.364  -13.225 1.00 51.69  ? 50  PRO D CD  1 
ATOM   10740 N  N   . GLY D 1 51  ? -35.631 32.260  -8.969  1.00 46.79  ? 51  GLY D N   1 
ATOM   10741 C  CA  . GLY D 1 51  ? -36.179 31.219  -8.130  1.00 47.62  ? 51  GLY D CA  1 
ATOM   10742 C  C   . GLY D 1 51  ? -35.218 30.111  -7.778  1.00 49.92  ? 51  GLY D C   1 
ATOM   10743 O  O   . GLY D 1 51  ? -35.645 29.114  -7.188  1.00 47.96  ? 51  GLY D O   1 
ATOM   10744 N  N   . LEU D 1 52  ? -33.936 30.245  -8.112  1.00 48.40  ? 52  LEU D N   1 
ATOM   10745 C  CA  . LEU D 1 52  ? -32.969 29.229  -7.709  1.00 43.45  ? 52  LEU D CA  1 
ATOM   10746 C  C   . LEU D 1 52  ? -31.698 29.810  -7.110  1.00 43.48  ? 52  LEU D C   1 
ATOM   10747 O  O   . LEU D 1 52  ? -31.204 29.273  -6.117  1.00 46.32  ? 52  LEU D O   1 
ATOM   10748 C  CB  . LEU D 1 52  ? -32.618 28.317  -8.898  1.00 45.20  ? 52  LEU D CB  1 
ATOM   10749 C  CG  . LEU D 1 52  ? -33.737 27.339  -9.262  1.00 41.01  ? 52  LEU D CG  1 
ATOM   10750 C  CD1 . LEU D 1 52  ? -33.380 26.459  -10.472 1.00 38.89  ? 52  LEU D CD1 1 
ATOM   10751 C  CD2 . LEU D 1 52  ? -34.113 26.471  -8.053  1.00 45.86  ? 52  LEU D CD2 1 
ATOM   10752 N  N   . VAL D 1 53  ? -31.154 30.882  -7.683  1.00 34.29  ? 53  VAL D N   1 
ATOM   10753 C  CA  . VAL D 1 53  ? -29.909 31.463  -7.199  1.00 42.67  ? 53  VAL D CA  1 
ATOM   10754 C  C   . VAL D 1 53  ? -29.952 32.958  -7.437  1.00 40.63  ? 53  VAL D C   1 
ATOM   10755 O  O   . VAL D 1 53  ? -30.524 33.430  -8.419  1.00 41.66  ? 53  VAL D O   1 
ATOM   10756 C  CB  . VAL D 1 53  ? -28.646 30.870  -7.877  1.00 48.89  ? 53  VAL D CB  1 
ATOM   10757 C  CG1 . VAL D 1 53  ? -28.336 29.471  -7.363  1.00 40.29  ? 53  VAL D CG1 1 
ATOM   10758 C  CG2 . VAL D 1 53  ? -28.788 30.877  -9.388  1.00 41.74  ? 53  VAL D CG2 1 
ATOM   10759 N  N   . ASP D 1 54  ? -29.320 33.703  -6.537  1.00 40.47  ? 54  ASP D N   1 
ATOM   10760 C  CA  . ASP D 1 54  ? -29.188 35.141  -6.714  1.00 40.25  ? 54  ASP D CA  1 
ATOM   10761 C  C   . ASP D 1 54  ? -28.037 35.655  -5.860  1.00 50.87  ? 54  ASP D C   1 
ATOM   10762 O  O   . ASP D 1 54  ? -28.244 36.365  -4.867  1.00 46.00  ? 54  ASP D O   1 
ATOM   10763 C  CB  . ASP D 1 54  ? -30.500 35.841  -6.367  1.00 43.98  ? 54  ASP D CB  1 
ATOM   10764 C  CG  . ASP D 1 54  ? -30.516 37.293  -6.774  1.00 48.47  ? 54  ASP D CG  1 
ATOM   10765 O  OD1 . ASP D 1 54  ? -29.439 37.868  -7.070  1.00 47.90  ? 54  ASP D OD1 1 
ATOM   10766 O  OD2 . ASP D 1 54  ? -31.624 37.865  -6.807  1.00 55.19  ? 54  ASP D OD2 1 
ATOM   10767 N  N   . VAL D 1 55  ? -26.817 35.296  -6.243  1.00 49.29  ? 55  VAL D N   1 
ATOM   10768 C  CA  . VAL D 1 55  ? -25.629 35.777  -5.560  1.00 40.06  ? 55  VAL D CA  1 
ATOM   10769 C  C   . VAL D 1 55  ? -25.166 37.069  -6.218  1.00 38.66  ? 55  VAL D C   1 
ATOM   10770 O  O   . VAL D 1 55  ? -25.520 37.387  -7.356  1.00 41.81  ? 55  VAL D O   1 
ATOM   10771 C  CB  . VAL D 1 55  ? -24.519 34.718  -5.570  1.00 40.60  ? 55  VAL D CB  1 
ATOM   10772 C  CG1 . VAL D 1 55  ? -25.070 33.383  -5.093  1.00 37.33  ? 55  VAL D CG1 1 
ATOM   10773 C  CG2 . VAL D 1 55  ? -23.967 34.573  -6.967  1.00 41.36  ? 55  VAL D CG2 1 
ATOM   10774 N  N   . GLY D 1 56  ? -24.375 37.832  -5.478  1.00 34.74  ? 56  GLY D N   1 
ATOM   10775 C  CA  . GLY D 1 56  ? -23.850 39.084  -5.955  1.00 42.37  ? 56  GLY D CA  1 
ATOM   10776 C  C   . GLY D 1 56  ? -22.418 38.928  -6.421  1.00 36.38  ? 56  GLY D C   1 
ATOM   10777 O  O   . GLY D 1 56  ? -21.839 37.842  -6.344  1.00 38.16  ? 56  GLY D O   1 
ATOM   10778 N  N   . PRO D 1 57  ? -21.802 40.029  -6.856  1.00 35.94  ? 57  PRO D N   1 
ATOM   10779 C  CA  . PRO D 1 57  ? -20.579 39.915  -7.666  1.00 39.95  ? 57  PRO D CA  1 
ATOM   10780 C  C   . PRO D 1 57  ? -19.380 39.323  -6.927  1.00 41.54  ? 57  PRO D C   1 
ATOM   10781 O  O   . PRO D 1 57  ? -18.420 38.894  -7.580  1.00 40.95  ? 57  PRO D O   1 
ATOM   10782 C  CB  . PRO D 1 57  ? -20.311 41.363  -8.096  1.00 38.25  ? 57  PRO D CB  1 
ATOM   10783 C  CG  . PRO D 1 57  ? -20.908 42.195  -6.984  1.00 44.41  ? 57  PRO D CG  1 
ATOM   10784 C  CD  . PRO D 1 57  ? -22.128 41.429  -6.520  1.00 40.79  ? 57  PRO D CD  1 
ATOM   10785 N  N   . ASP D 1 58  ? -19.396 39.270  -5.602  1.00 38.75  ? 58  ASP D N   1 
ATOM   10786 C  CA  . ASP D 1 58  ? -18.232 38.841  -4.847  1.00 39.79  ? 58  ASP D CA  1 
ATOM   10787 C  C   . ASP D 1 58  ? -18.300 37.376  -4.427  1.00 36.06  ? 58  ASP D C   1 
ATOM   10788 O  O   . ASP D 1 58  ? -17.392 36.904  -3.734  1.00 38.87  ? 58  ASP D O   1 
ATOM   10789 C  CB  . ASP D 1 58  ? -18.044 39.743  -3.615  1.00 41.85  ? 58  ASP D CB  1 
ATOM   10790 C  CG  . ASP D 1 58  ? -19.162 39.587  -2.587  1.00 45.76  ? 58  ASP D CG  1 
ATOM   10791 O  OD1 . ASP D 1 58  ? -20.306 39.264  -2.972  1.00 46.20  ? 58  ASP D OD1 1 
ATOM   10792 O  OD2 . ASP D 1 58  ? -18.901 39.814  -1.387  1.00 54.29  ? 58  ASP D OD2 1 
ATOM   10793 N  N   . VAL D 1 59  ? -19.322 36.637  -4.851  1.00 36.64  ? 59  VAL D N   1 
ATOM   10794 C  CA  . VAL D 1 59  ? -19.554 35.281  -4.337  1.00 36.53  ? 59  VAL D CA  1 
ATOM   10795 C  C   . VAL D 1 59  ? -18.977 34.177  -5.230  1.00 36.21  ? 59  VAL D C   1 
ATOM   10796 O  O   . VAL D 1 59  ? -18.285 33.287  -4.714  1.00 28.27  ? 59  VAL D O   1 
ATOM   10797 C  CB  . VAL D 1 59  ? -21.059 35.049  -4.082  1.00 35.27  ? 59  VAL D CB  1 
ATOM   10798 C  CG1 . VAL D 1 59  ? -21.362 33.574  -3.898  1.00 35.89  ? 59  VAL D CG1 1 
ATOM   10799 C  CG2 . VAL D 1 59  ? -21.529 35.855  -2.868  1.00 38.87  ? 59  VAL D CG2 1 
ATOM   10800 N  N   . PRO D 1 60  ? -19.222 34.149  -6.546  1.00 34.50  ? 60  PRO D N   1 
ATOM   10801 C  CA  . PRO D 1 60  ? -18.786 32.977  -7.330  1.00 31.16  ? 60  PRO D CA  1 
ATOM   10802 C  C   . PRO D 1 60  ? -17.268 32.827  -7.325  1.00 25.54  ? 60  PRO D C   1 
ATOM   10803 O  O   . PRO D 1 60  ? -16.531 33.800  -7.174  1.00 32.60  ? 60  PRO D O   1 
ATOM   10804 C  CB  . PRO D 1 60  ? -19.326 33.268  -8.740  1.00 31.85  ? 60  PRO D CB  1 
ATOM   10805 C  CG  . PRO D 1 60  ? -20.457 34.261  -8.517  1.00 31.67  ? 60  PRO D CG  1 
ATOM   10806 C  CD  . PRO D 1 60  ? -19.990 35.104  -7.364  1.00 27.86  ? 60  PRO D CD  1 
ATOM   10807 N  N   . LEU D 1 61  ? -16.798 31.588  -7.428  1.00 28.81  ? 61  LEU D N   1 
ATOM   10808 C  CA  . LEU D 1 61  ? -15.363 31.351  -7.536  1.00 30.39  ? 61  LEU D CA  1 
ATOM   10809 C  C   . LEU D 1 61  ? -14.964 31.267  -9.007  1.00 29.91  ? 61  LEU D C   1 
ATOM   10810 O  O   . LEU D 1 61  ? -15.784 30.947  -9.871  1.00 27.52  ? 61  LEU D O   1 
ATOM   10811 C  CB  . LEU D 1 61  ? -14.954 30.072  -6.810  1.00 27.83  ? 61  LEU D CB  1 
ATOM   10812 C  CG  . LEU D 1 61  ? -15.492 29.932  -5.387  1.00 30.25  ? 61  LEU D CG  1 
ATOM   10813 C  CD1 . LEU D 1 61  ? -14.886 28.727  -4.722  1.00 30.39  ? 61  LEU D CD1 1 
ATOM   10814 C  CD2 . LEU D 1 61  ? -15.193 31.193  -4.602  1.00 31.83  ? 61  LEU D CD2 1 
ATOM   10815 N  N   . TRP D 1 62  ? -13.684 31.546  -9.281  1.00 28.28  ? 62  TRP D N   1 
ATOM   10816 C  CA  . TRP D 1 62  ? -13.159 31.658  -10.641 1.00 28.06  ? 62  TRP D CA  1 
ATOM   10817 C  C   . TRP D 1 62  ? -12.010 30.686  -10.847 1.00 26.00  ? 62  TRP D C   1 
ATOM   10818 O  O   . TRP D 1 62  ? -10.980 30.783  -10.167 1.00 23.94  ? 62  TRP D O   1 
ATOM   10819 C  CB  . TRP D 1 62  ? -12.643 33.073  -10.931 1.00 24.31  ? 62  TRP D CB  1 
ATOM   10820 C  CG  . TRP D 1 62  ? -13.659 34.136  -11.015 1.00 28.76  ? 62  TRP D CG  1 
ATOM   10821 C  CD1 . TRP D 1 62  ? -14.419 34.636  -9.998  1.00 30.07  ? 62  TRP D CD1 1 
ATOM   10822 C  CD2 . TRP D 1 62  ? -14.012 34.883  -12.188 1.00 29.18  ? 62  TRP D CD2 1 
ATOM   10823 N  NE1 . TRP D 1 62  ? -15.233 35.643  -10.468 1.00 31.86  ? 62  TRP D NE1 1 
ATOM   10824 C  CE2 . TRP D 1 62  ? -15.004 35.809  -11.811 1.00 29.10  ? 62  TRP D CE2 1 
ATOM   10825 C  CE3 . TRP D 1 62  ? -13.591 34.846  -13.525 1.00 26.56  ? 62  TRP D CE3 1 
ATOM   10826 C  CZ2 . TRP D 1 62  ? -15.585 36.692  -12.719 1.00 27.01  ? 62  TRP D CZ2 1 
ATOM   10827 C  CZ3 . TRP D 1 62  ? -14.179 35.726  -14.431 1.00 28.88  ? 62  TRP D CZ3 1 
ATOM   10828 C  CH2 . TRP D 1 62  ? -15.157 36.639  -14.017 1.00 31.08  ? 62  TRP D CH2 1 
ATOM   10829 N  N   . THR D 1 63  ? -12.141 29.807  -11.834 1.00 24.13  ? 63  THR D N   1 
ATOM   10830 C  CA  . THR D 1 63  ? -11.017 28.990  -12.255 1.00 22.94  ? 63  THR D CA  1 
ATOM   10831 C  C   . THR D 1 63  ? -10.377 29.640  -13.485 1.00 26.25  ? 63  THR D C   1 
ATOM   10832 O  O   . THR D 1 63  ? -11.059 29.901  -14.482 1.00 25.14  ? 63  THR D O   1 
ATOM   10833 C  CB  . THR D 1 63  ? -11.460 27.560  -12.517 1.00 24.68  ? 63  THR D CB  1 
ATOM   10834 O  OG1 . THR D 1 63  ? -12.005 27.027  -11.298 1.00 29.57  ? 63  THR D OG1 1 
ATOM   10835 C  CG2 . THR D 1 63  ? -10.283 26.703  -12.949 1.00 26.00  ? 63  THR D CG2 1 
ATOM   10836 N  N   . LEU D 1 64  ? -9.084  29.960  -13.379 1.00 24.74  ? 64  LEU D N   1 
ATOM   10837 C  CA  . LEU D 1 64  ? -8.324  30.610  -14.441 1.00 23.77  ? 64  LEU D CA  1 
ATOM   10838 C  C   . LEU D 1 64  ? -6.934  30.015  -14.420 1.00 32.28  ? 64  LEU D C   1 
ATOM   10839 O  O   . LEU D 1 64  ? -6.325  29.918  -13.349 1.00 28.65  ? 64  LEU D O   1 
ATOM   10840 C  CB  . LEU D 1 64  ? -8.232  32.122  -14.252 1.00 24.23  ? 64  LEU D CB  1 
ATOM   10841 C  CG  . LEU D 1 64  ? -9.540  32.905  -14.226 1.00 26.96  ? 64  LEU D CG  1 
ATOM   10842 C  CD1 . LEU D 1 64  ? -9.321  34.314  -13.626 1.00 22.11  ? 64  LEU D CD1 1 
ATOM   10843 C  CD2 . LEU D 1 64  ? -10.123 32.955  -15.618 1.00 22.90  ? 64  LEU D CD2 1 
ATOM   10844 N  N   . GLN D 1 65  ? -6.453  29.587  -15.595 1.00 27.64  ? 65  GLN D N   1 
ATOM   10845 C  CA  . GLN D 1 65  ? -5.121  29.011  -15.709 1.00 24.55  ? 65  GLN D CA  1 
ATOM   10846 C  C   . GLN D 1 65  ? -4.928  27.878  -14.694 1.00 26.71  ? 65  GLN D C   1 
ATOM   10847 O  O   . GLN D 1 65  ? -3.858  27.717  -14.100 1.00 27.63  ? 65  GLN D O   1 
ATOM   10848 C  CB  . GLN D 1 65  ? -4.046  30.100  -15.559 1.00 25.29  ? 65  GLN D CB  1 
ATOM   10849 C  CG  . GLN D 1 65  ? -4.252  31.297  -16.512 1.00 27.57  ? 65  GLN D CG  1 
ATOM   10850 C  CD  . GLN D 1 65  ? -3.096  32.275  -16.540 1.00 24.54  ? 65  GLN D CD  1 
ATOM   10851 O  OE1 . GLN D 1 65  ? -2.763  32.916  -15.542 1.00 30.32  ? 65  GLN D OE1 1 
ATOM   10852 N  NE2 . GLN D 1 65  ? -2.495  32.417  -17.696 1.00 21.89  ? 65  GLN D NE2 1 
ATOM   10853 N  N   . GLY D 1 66  ? -5.984  27.089  -14.495 1.00 28.57  ? 66  GLY D N   1 
ATOM   10854 C  CA  . GLY D 1 66  ? -5.905  25.807  -13.803 1.00 28.37  ? 66  GLY D CA  1 
ATOM   10855 C  C   . GLY D 1 66  ? -6.026  25.850  -12.297 1.00 29.87  ? 66  GLY D C   1 
ATOM   10856 O  O   . GLY D 1 66  ? -5.765  24.836  -11.643 1.00 35.29  ? 66  GLY D O   1 
ATOM   10857 N  N   . GLN D 1 67  ? -6.387  26.989  -11.725 1.00 25.67  ? 67  GLN D N   1 
ATOM   10858 C  CA  . GLN D 1 67  ? -6.478  27.168  -10.290 1.00 26.23  ? 67  GLN D CA  1 
ATOM   10859 C  C   . GLN D 1 67  ? -7.732  27.973  -10.013 1.00 26.60  ? 67  GLN D C   1 
ATOM   10860 O  O   . GLN D 1 67  ? -8.128  28.807  -10.832 1.00 25.48  ? 67  GLN D O   1 
ATOM   10861 C  CB  . GLN D 1 67  ? -5.261  27.903  -9.734  1.00 29.20  ? 67  GLN D CB  1 
ATOM   10862 C  CG  . GLN D 1 67  ? -4.060  27.034  -9.442  1.00 34.58  ? 67  GLN D CG  1 
ATOM   10863 C  CD  . GLN D 1 67  ? -3.062  27.740  -8.542  1.00 41.08  ? 67  GLN D CD  1 
ATOM   10864 O  OE1 . GLN D 1 67  ? -3.416  28.227  -7.461  1.00 42.48  ? 67  GLN D OE1 1 
ATOM   10865 N  NE2 . GLN D 1 67  ? -1.811  27.822  -8.994  1.00 45.60  ? 67  GLN D NE2 1 
ATOM   10866 N  N   . GLN D 1 68  ? -8.349  27.741  -8.853  1.00 21.26  ? 68  GLN D N   1 
ATOM   10867 C  CA  . GLN D 1 68  ? -9.600  28.394  -8.499  1.00 20.55  ? 68  GLN D CA  1 
ATOM   10868 C  C   . GLN D 1 68  ? -9.361  29.424  -7.401  1.00 26.33  ? 68  GLN D C   1 
ATOM   10869 O  O   . GLN D 1 68  ? -8.613  29.171  -6.454  1.00 28.29  ? 68  GLN D O   1 
ATOM   10870 C  CB  . GLN D 1 68  ? -10.637 27.363  -8.056  1.00 28.60  ? 68  GLN D CB  1 
ATOM   10871 C  CG  . GLN D 1 68  ? -11.979 27.937  -7.682  1.00 27.67  ? 68  GLN D CG  1 
ATOM   10872 C  CD  . GLN D 1 68  ? -12.956 26.853  -7.271  1.00 29.23  ? 68  GLN D CD  1 
ATOM   10873 O  OE1 . GLN D 1 68  ? -12.778 26.197  -6.244  1.00 28.40  ? 68  GLN D OE1 1 
ATOM   10874 N  NE2 . GLN D 1 68  ? -13.978 26.637  -8.089  1.00 27.59  ? 68  GLN D NE2 1 
ATOM   10875 N  N   . TYR D 1 69  ? -10.028 30.567  -7.528  1.00 22.38  ? 69  TYR D N   1 
ATOM   10876 C  CA  . TYR D 1 69  ? -9.804  31.753  -6.715  1.00 25.18  ? 69  TYR D CA  1 
ATOM   10877 C  C   . TYR D 1 69  ? -11.130 32.357  -6.281  1.00 27.47  ? 69  TYR D C   1 
ATOM   10878 O  O   . TYR D 1 69  ? -12.123 32.289  -7.010  1.00 22.84  ? 69  TYR D O   1 
ATOM   10879 C  CB  . TYR D 1 69  ? -9.032  32.839  -7.490  1.00 23.44  ? 69  TYR D CB  1 
ATOM   10880 C  CG  . TYR D 1 69  ? -7.710  32.401  -8.039  1.00 21.93  ? 69  TYR D CG  1 
ATOM   10881 C  CD1 . TYR D 1 69  ? -6.585  32.400  -7.234  1.00 24.62  ? 69  TYR D CD1 1 
ATOM   10882 C  CD2 . TYR D 1 69  ? -7.567  31.987  -9.373  1.00 26.27  ? 69  TYR D CD2 1 
ATOM   10883 C  CE1 . TYR D 1 69  ? -5.344  32.005  -7.729  1.00 26.05  ? 69  TYR D CE1 1 
ATOM   10884 C  CE2 . TYR D 1 69  ? -6.314  31.589  -9.879  1.00 25.05  ? 69  TYR D CE2 1 
ATOM   10885 C  CZ  . TYR D 1 69  ? -5.209  31.607  -9.038  1.00 25.28  ? 69  TYR D CZ  1 
ATOM   10886 O  OH  . TYR D 1 69  ? -3.958  31.219  -9.458  1.00 24.60  ? 69  TYR D OH  1 
ATOM   10887 N  N   . THR D 1 70  ? -11.127 33.002  -5.109  1.00 28.38  ? 70  THR D N   1 
ATOM   10888 C  CA  . THR D 1 70  ? -12.179 33.962  -4.803  1.00 25.37  ? 70  THR D CA  1 
ATOM   10889 C  C   . THR D 1 70  ? -11.877 35.310  -5.452  1.00 28.90  ? 70  THR D C   1 
ATOM   10890 O  O   . THR D 1 70  ? -10.731 35.633  -5.776  1.00 29.10  ? 70  THR D O   1 
ATOM   10891 C  CB  . THR D 1 70  ? -12.314 34.184  -3.297  1.00 29.98  ? 70  THR D CB  1 
ATOM   10892 O  OG1 . THR D 1 70  ? -11.100 34.760  -2.803  1.00 29.54  ? 70  THR D OG1 1 
ATOM   10893 C  CG2 . THR D 1 70  ? -12.585 32.882  -2.562  1.00 24.16  ? 70  THR D CG2 1 
ATOM   10894 N  N   . LEU D 1 71  ? -12.915 36.135  -5.582  1.00 28.73  ? 71  LEU D N   1 
ATOM   10895 C  CA  . LEU D 1 71  ? -12.690 37.493  -6.069  1.00 32.74  ? 71  LEU D CA  1 
ATOM   10896 C  C   . LEU D 1 71  ? -11.629 38.219  -5.254  1.00 32.13  ? 71  LEU D C   1 
ATOM   10897 O  O   . LEU D 1 71  ? -10.774 38.922  -5.812  1.00 29.37  ? 71  LEU D O   1 
ATOM   10898 C  CB  . LEU D 1 71  ? -13.991 38.292  -6.046  1.00 31.85  ? 71  LEU D CB  1 
ATOM   10899 C  CG  . LEU D 1 71  ? -13.794 39.650  -6.695  1.00 35.46  ? 71  LEU D CG  1 
ATOM   10900 C  CD1 . LEU D 1 71  ? -13.274 39.419  -8.118  1.00 32.18  ? 71  LEU D CD1 1 
ATOM   10901 C  CD2 . LEU D 1 71  ? -15.099 40.416  -6.697  1.00 34.19  ? 71  LEU D CD2 1 
ATOM   10902 N  N   . ALA D 1 72  ? -11.669 38.064  -3.923  1.00 30.21  ? 72  ALA D N   1 
ATOM   10903 C  CA  . ALA D 1 72  ? -10.699 38.742  -3.069  1.00 25.88  ? 72  ALA D CA  1 
ATOM   10904 C  C   . ALA D 1 72  ? -9.279  38.285  -3.378  1.00 28.85  ? 72  ALA D C   1 
ATOM   10905 O  O   . ALA D 1 72  ? -8.338  39.087  -3.345  1.00 30.12  ? 72  ALA D O   1 
ATOM   10906 C  CB  . ALA D 1 72  ? -11.035 38.494  -1.599  1.00 36.20  ? 72  ALA D CB  1 
ATOM   10907 N  N   . GLU D 1 73  ? -9.099  36.997  -3.673  1.00 25.72  ? 73  GLU D N   1 
ATOM   10908 C  CA  . GLU D 1 73  ? -7.778  36.525  -4.074  1.00 25.80  ? 73  GLU D CA  1 
ATOM   10909 C  C   . GLU D 1 73  ? -7.365  37.142  -5.404  1.00 25.64  ? 73  GLU D C   1 
ATOM   10910 O  O   . GLU D 1 73  ? -6.243  37.634  -5.545  1.00 27.55  ? 73  GLU D O   1 
ATOM   10911 C  CB  . GLU D 1 73  ? -7.769  35.006  -4.156  1.00 21.73  ? 73  GLU D CB  1 
ATOM   10912 C  CG  . GLU D 1 73  ? -7.820  34.372  -2.771  1.00 27.75  ? 73  GLU D CG  1 
ATOM   10913 C  CD  . GLU D 1 73  ? -8.066  32.882  -2.792  1.00 29.11  ? 73  GLU D CD  1 
ATOM   10914 O  OE1 . GLU D 1 73  ? -8.782  32.400  -3.689  1.00 31.49  ? 73  GLU D OE1 1 
ATOM   10915 O  OE2 . GLU D 1 73  ? -7.534  32.189  -1.900  1.00 31.90  ? 73  GLU D OE2 1 
ATOM   10916 N  N   . LEU D 1 74  ? -8.271  37.139  -6.385  1.00 28.76  ? 74  LEU D N   1 
ATOM   10917 C  CA  . LEU D 1 74  ? -7.941  37.688  -7.700  1.00 26.09  ? 74  LEU D CA  1 
ATOM   10918 C  C   . LEU D 1 74  ? -7.432  39.105  -7.562  1.00 26.26  ? 74  LEU D C   1 
ATOM   10919 O  O   . LEU D 1 74  ? -6.426  39.472  -8.167  1.00 30.35  ? 74  LEU D O   1 
ATOM   10920 C  CB  . LEU D 1 74  ? -9.164  37.650  -8.619  1.00 30.77  ? 74  LEU D CB  1 
ATOM   10921 C  CG  . LEU D 1 74  ? -9.679  36.283  -9.072  1.00 28.81  ? 74  LEU D CG  1 
ATOM   10922 C  CD1 . LEU D 1 74  ? -10.836 36.456  -10.048 1.00 30.65  ? 74  LEU D CD1 1 
ATOM   10923 C  CD2 . LEU D 1 74  ? -8.593  35.473  -9.714  1.00 24.02  ? 74  LEU D CD2 1 
ATOM   10924 N  N   . TRP D 1 75  ? -8.054  39.874  -6.674  1.00 28.62  ? 75  TRP D N   1 
ATOM   10925 C  CA  . TRP D 1 75  ? -7.688  41.270  -6.470  1.00 28.63  ? 75  TRP D CA  1 
ATOM   10926 C  C   . TRP D 1 75  ? -6.250  41.437  -5.962  1.00 31.24  ? 75  TRP D C   1 
ATOM   10927 O  O   . TRP D 1 75  ? -5.573  42.412  -6.315  1.00 31.57  ? 75  TRP D O   1 
ATOM   10928 C  CB  . TRP D 1 75  ? -8.692  41.891  -5.511  1.00 28.95  ? 75  TRP D CB  1 
ATOM   10929 C  CG  . TRP D 1 75  ? -9.979  42.259  -6.185  1.00 32.01  ? 75  TRP D CG  1 
ATOM   10930 C  CD1 . TRP D 1 75  ? -10.226 42.263  -7.531  1.00 36.12  ? 75  TRP D CD1 1 
ATOM   10931 C  CD2 . TRP D 1 75  ? -11.187 42.708  -5.559  1.00 34.14  ? 75  TRP D CD2 1 
ATOM   10932 N  NE1 . TRP D 1 75  ? -11.513 42.680  -7.780  1.00 35.86  ? 75  TRP D NE1 1 
ATOM   10933 C  CE2 . TRP D 1 75  ? -12.125 42.959  -6.587  1.00 33.63  ? 75  TRP D CE2 1 
ATOM   10934 C  CE3 . TRP D 1 75  ? -11.570 42.920  -4.231  1.00 32.44  ? 75  TRP D CE3 1 
ATOM   10935 C  CZ2 . TRP D 1 75  ? -13.418 43.417  -6.326  1.00 36.88  ? 75  TRP D CZ2 1 
ATOM   10936 C  CZ3 . TRP D 1 75  ? -12.858 43.366  -3.972  1.00 33.68  ? 75  TRP D CZ3 1 
ATOM   10937 C  CH2 . TRP D 1 75  ? -13.768 43.605  -5.014  1.00 34.25  ? 75  TRP D CH2 1 
ATOM   10938 N  N   . ASP D 1 76  ? -5.758  40.512  -5.138  1.00 31.55  ? 76  ASP D N   1 
ATOM   10939 C  CA  . ASP D 1 76  ? -4.413  40.647  -4.586  1.00 30.89  ? 76  ASP D CA  1 
ATOM   10940 C  C   . ASP D 1 76  ? -3.366  39.825  -5.325  1.00 32.49  ? 76  ASP D C   1 
ATOM   10941 O  O   . ASP D 1 76  ? -2.179  39.928  -5.003  1.00 33.69  ? 76  ASP D O   1 
ATOM   10942 C  CB  . ASP D 1 76  ? -4.399  40.261  -3.096  1.00 36.62  ? 76  ASP D CB  1 
ATOM   10943 C  CG  . ASP D 1 76  ? -5.001  41.339  -2.203  1.00 38.42  ? 76  ASP D CG  1 
ATOM   10944 O  OD1 . ASP D 1 76  ? -5.395  42.398  -2.741  1.00 45.77  ? 76  ASP D OD1 1 
ATOM   10945 O  OD2 . ASP D 1 76  ? -5.066  41.136  -0.965  1.00 46.37  ? 76  ASP D OD2 1 
ATOM   10946 N  N   . GLY D 1 77  ? -3.765  39.014  -6.301  1.00 32.22  ? 77  GLY D N   1 
ATOM   10947 C  CA  . GLY D 1 77  ? -2.813  38.161  -6.978  1.00 32.28  ? 77  GLY D CA  1 
ATOM   10948 C  C   . GLY D 1 77  ? -2.096  38.839  -8.140  1.00 28.67  ? 77  GLY D C   1 
ATOM   10949 O  O   . GLY D 1 77  ? -2.561  39.829  -8.708  1.00 32.54  ? 77  GLY D O   1 
ATOM   10950 N  N   . ASP D 1 78  ? -0.942  38.263  -8.487  1.00 27.52  ? 78  ASP D N   1 
ATOM   10951 C  CA  . ASP D 1 78  ? -0.091  38.715  -9.582  1.00 34.72  ? 78  ASP D CA  1 
ATOM   10952 C  C   . ASP D 1 78  ? 0.125   37.569  -10.569 1.00 31.46  ? 78  ASP D C   1 
ATOM   10953 O  O   . ASP D 1 78  ? 0.261   36.411  -10.161 1.00 29.92  ? 78  ASP D O   1 
ATOM   10954 C  CB  . ASP D 1 78  ? 1.273   39.185  -9.070  1.00 30.30  ? 78  ASP D CB  1 
ATOM   10955 C  CG  . ASP D 1 78  ? 1.439   40.703  -9.106  1.00 47.14  ? 78  ASP D CG  1 
ATOM   10956 O  OD1 . ASP D 1 78  ? 0.495   41.386  -9.553  1.00 48.51  ? 78  ASP D OD1 1 
ATOM   10957 O  OD2 . ASP D 1 78  ? 2.533   41.208  -8.732  1.00 46.83  ? 78  ASP D OD2 1 
ATOM   10958 N  N   . GLY D 1 79  ? 0.158   37.891  -11.865 1.00 31.21  ? 79  GLY D N   1 
ATOM   10959 C  CA  . GLY D 1 79  ? 0.530   36.933  -12.904 1.00 34.04  ? 79  GLY D CA  1 
ATOM   10960 C  C   . GLY D 1 79  ? -0.569  36.016  -13.398 1.00 30.74  ? 79  GLY D C   1 
ATOM   10961 O  O   . GLY D 1 79  ? -0.409  35.377  -14.452 1.00 33.75  ? 79  GLY D O   1 
ATOM   10962 N  N   . VAL D 1 80  ? -1.666  35.906  -12.670 1.00 31.35  ? 80  VAL D N   1 
ATOM   10963 C  CA  . VAL D 1 80  ? -2.812  35.139  -13.134 1.00 28.80  ? 80  VAL D CA  1 
ATOM   10964 C  C   . VAL D 1 80  ? -3.550  35.974  -14.172 1.00 26.27  ? 80  VAL D C   1 
ATOM   10965 O  O   . VAL D 1 80  ? -3.766  37.172  -13.978 1.00 24.19  ? 80  VAL D O   1 
ATOM   10966 C  CB  . VAL D 1 80  ? -3.714  34.756  -11.949 1.00 26.38  ? 80  VAL D CB  1 
ATOM   10967 C  CG1 . VAL D 1 80  ? -4.918  33.980  -12.404 1.00 20.79  ? 80  VAL D CG1 1 
ATOM   10968 C  CG2 . VAL D 1 80  ? -2.921  33.924  -10.941 1.00 28.32  ? 80  VAL D CG2 1 
ATOM   10969 N  N   . ARG D 1 81  ? -3.901  35.360  -15.296 1.00 25.46  ? 81  ARG D N   1 
ATOM   10970 C  CA  . ARG D 1 81  ? -4.646  36.053  -16.332 1.00 25.26  ? 81  ARG D CA  1 
ATOM   10971 C  C   . ARG D 1 81  ? -6.001  35.401  -16.544 1.00 24.55  ? 81  ARG D C   1 
ATOM   10972 O  O   . ARG D 1 81  ? -6.257  34.280  -16.105 1.00 27.35  ? 81  ARG D O   1 
ATOM   10973 C  CB  . ARG D 1 81  ? -3.879  36.074  -17.656 1.00 23.43  ? 81  ARG D CB  1 
ATOM   10974 C  CG  . ARG D 1 81  ? -2.516  36.721  -17.538 1.00 29.51  ? 81  ARG D CG  1 
ATOM   10975 C  CD  . ARG D 1 81  ? -1.805  36.927  -18.883 1.00 29.55  ? 81  ARG D CD  1 
ATOM   10976 N  NE  . ARG D 1 81  ? -2.667  37.395  -19.965 1.00 24.15  ? 81  ARG D NE  1 
ATOM   10977 C  CZ  . ARG D 1 81  ? -2.963  38.664  -20.196 1.00 29.73  ? 81  ARG D CZ  1 
ATOM   10978 N  NH1 . ARG D 1 81  ? -2.573  39.625  -19.374 1.00 30.46  ? 81  ARG D NH1 1 
ATOM   10979 N  NH2 . ARG D 1 81  ? -3.656  38.979  -21.286 1.00 31.42  ? 81  ARG D NH2 1 
ATOM   10980 N  N   . TRP D 1 82  ? -6.862  36.128  -17.235 1.00 29.49  ? 82  TRP D N   1 
ATOM   10981 C  CA  . TRP D 1 82  ? -7.978  35.526  -17.949 1.00 21.75  ? 82  TRP D CA  1 
ATOM   10982 C  C   . TRP D 1 82  ? -7.613  35.530  -19.426 1.00 24.66  ? 82  TRP D C   1 
ATOM   10983 O  O   . TRP D 1 82  ? -7.830  36.533  -20.116 1.00 26.73  ? 82  TRP D O   1 
ATOM   10984 C  CB  . TRP D 1 82  ? -9.270  36.296  -17.694 1.00 24.82  ? 82  TRP D CB  1 
ATOM   10985 C  CG  . TRP D 1 82  ? -10.508 35.723  -18.367 1.00 24.88  ? 82  TRP D CG  1 
ATOM   10986 C  CD1 . TRP D 1 82  ? -10.571 34.659  -19.228 1.00 24.48  ? 82  TRP D CD1 1 
ATOM   10987 C  CD2 . TRP D 1 82  ? -11.849 36.214  -18.236 1.00 22.40  ? 82  TRP D CD2 1 
ATOM   10988 N  NE1 . TRP D 1 82  ? -11.881 34.455  -19.635 1.00 25.38  ? 82  TRP D NE1 1 
ATOM   10989 C  CE2 . TRP D 1 82  ? -12.680 35.391  -19.029 1.00 24.44  ? 82  TRP D CE2 1 
ATOM   10990 C  CE3 . TRP D 1 82  ? -12.428 37.261  -17.515 1.00 24.07  ? 82  TRP D CE3 1 
ATOM   10991 C  CZ2 . TRP D 1 82  ? -14.058 35.589  -19.123 1.00 25.82  ? 82  TRP D CZ2 1 
ATOM   10992 C  CZ3 . TRP D 1 82  ? -13.808 37.452  -17.606 1.00 21.27  ? 82  TRP D CZ3 1 
ATOM   10993 C  CH2 . TRP D 1 82  ? -14.598 36.627  -18.415 1.00 25.06  ? 82  TRP D CH2 1 
ATOM   10994 N  N   . PRO D 1 83  ? -7.030  34.458  -19.948 1.00 30.43  ? 83  PRO D N   1 
ATOM   10995 C  CA  . PRO D 1 83  ? -6.598  34.483  -21.351 1.00 28.13  ? 83  PRO D CA  1 
ATOM   10996 C  C   . PRO D 1 83  ? -7.786  34.535  -22.295 1.00 27.01  ? 83  PRO D C   1 
ATOM   10997 O  O   . PRO D 1 83  ? -8.800  33.867  -22.079 1.00 21.75  ? 83  PRO D O   1 
ATOM   10998 C  CB  . PRO D 1 83  ? -5.801  33.182  -21.510 1.00 27.55  ? 83  PRO D CB  1 
ATOM   10999 C  CG  . PRO D 1 83  ? -5.441  32.766  -20.060 1.00 26.18  ? 83  PRO D CG  1 
ATOM   11000 C  CD  . PRO D 1 83  ? -6.663  33.205  -19.275 1.00 24.95  ? 83  PRO D CD  1 
ATOM   11001 N  N   . LEU D 1 84  ? -7.648  35.358  -23.347 1.00 25.71  ? 84  LEU D N   1 
ATOM   11002 C  CA  . LEU D 1 84  ? -8.683  35.475  -24.374 1.00 23.58  ? 84  LEU D CA  1 
ATOM   11003 C  C   . LEU D 1 84  ? -9.106  34.125  -24.912 1.00 25.75  ? 84  LEU D C   1 
ATOM   11004 O  O   . LEU D 1 84  ? -10.303 33.873  -25.132 1.00 26.46  ? 84  LEU D O   1 
ATOM   11005 C  CB  . LEU D 1 84  ? -8.178  36.326  -25.555 1.00 25.03  ? 84  LEU D CB  1 
ATOM   11006 C  CG  . LEU D 1 84  ? -9.145  36.474  -26.726 1.00 20.64  ? 84  LEU D CG  1 
ATOM   11007 C  CD1 . LEU D 1 84  ? -10.506 37.017  -26.281 1.00 27.92  ? 84  LEU D CD1 1 
ATOM   11008 C  CD2 . LEU D 1 84  ? -8.566  37.410  -27.765 1.00 24.31  ? 84  LEU D CD2 1 
ATOM   11009 N  N   . GLU D 1 85  ? -8.136  33.261  -25.184 1.00 25.44  ? 85  GLU D N   1 
ATOM   11010 C  CA  . GLU D 1 85  ? -8.444  31.955  -25.739 1.00 24.73  ? 85  GLU D CA  1 
ATOM   11011 C  C   . GLU D 1 85  ? -9.185  31.047  -24.749 1.00 30.79  ? 85  GLU D C   1 
ATOM   11012 O  O   . GLU D 1 85  ? -9.636  29.964  -25.140 1.00 22.94  ? 85  GLU D O   1 
ATOM   11013 C  CB  . GLU D 1 85  ? -7.143  31.306  -26.203 1.00 24.83  ? 85  GLU D CB  1 
ATOM   11014 C  CG  . GLU D 1 85  ? -6.220  30.897  -25.064 1.00 29.09  ? 85  GLU D CG  1 
ATOM   11015 C  CD  . GLU D 1 85  ? -5.185  31.958  -24.735 1.00 26.07  ? 85  GLU D CD  1 
ATOM   11016 O  OE1 . GLU D 1 85  ? -5.474  33.150  -24.947 1.00 29.12  ? 85  GLU D OE1 1 
ATOM   11017 O  OE2 . GLU D 1 85  ? -4.089  31.606  -24.249 1.00 25.91  ? 85  GLU D OE2 1 
ATOM   11018 N  N   . ASP D 1 86  ? -9.352  31.458  -23.494 1.00 24.30  ? 86  ASP D N   1 
ATOM   11019 C  CA  . ASP D 1 86  ? -9.905  30.570  -22.462 1.00 23.36  ? 86  ASP D CA  1 
ATOM   11020 C  C   . ASP D 1 86  ? -11.216 31.121  -21.918 1.00 21.40  ? 86  ASP D C   1 
ATOM   11021 O  O   . ASP D 1 86  ? -11.264 32.267  -21.463 1.00 26.45  ? 86  ASP D O   1 
ATOM   11022 C  CB  . ASP D 1 86  ? -8.951  30.435  -21.277 1.00 24.65  ? 86  ASP D CB  1 
ATOM   11023 C  CG  . ASP D 1 86  ? -7.796  29.537  -21.535 1.00 22.75  ? 86  ASP D CG  1 
ATOM   11024 O  OD1 . ASP D 1 86  ? -7.784  28.806  -22.535 1.00 27.18  ? 86  ASP D OD1 1 
ATOM   11025 O  OD2 . ASP D 1 86  ? -6.863  29.596  -20.713 1.00 25.98  ? 86  ASP D OD2 1 
ATOM   11026 N  N   . ALA D 1 87  ? -12.257 30.302  -21.873 1.00 27.01  ? 87  ALA D N   1 
ATOM   11027 C  CA  . ALA D 1 87  ? -13.431 30.760  -21.139 1.00 26.75  ? 87  ALA D CA  1 
ATOM   11028 C  C   . ALA D 1 87  ? -13.145 30.779  -19.634 1.00 29.24  ? 87  ALA D C   1 
ATOM   11029 O  O   . ALA D 1 87  ? -12.447 29.914  -19.096 1.00 29.23  ? 87  ALA D O   1 
ATOM   11030 C  CB  . ALA D 1 87  ? -14.641 29.883  -21.440 1.00 30.09  ? 87  ALA D CB  1 
ATOM   11031 N  N   . ALA D 1 88  ? -13.680 31.768  -18.939 1.00 23.30  ? 88  ALA D N   1 
ATOM   11032 C  CA  . ALA D 1 88  ? -13.580 31.662  -17.500 1.00 24.83  ? 88  ALA D CA  1 
ATOM   11033 C  C   . ALA D 1 88  ? -14.513 30.548  -17.037 1.00 24.63  ? 88  ALA D C   1 
ATOM   11034 O  O   . ALA D 1 88  ? -15.537 30.280  -17.661 1.00 29.91  ? 88  ALA D O   1 
ATOM   11035 C  CB  . ALA D 1 88  ? -13.915 32.999  -16.835 1.00 26.91  ? 88  ALA D CB  1 
ATOM   11036 N  N   . ILE D 1 89  ? -14.131 29.855  -15.967 1.00 25.92  ? 89  ILE D N   1 
ATOM   11037 C  CA  . ILE D 1 89  ? -14.977 28.821  -15.373 1.00 30.88  ? 89  ILE D CA  1 
ATOM   11038 C  C   . ILE D 1 89  ? -15.497 29.367  -14.049 1.00 26.63  ? 89  ILE D C   1 
ATOM   11039 O  O   . ILE D 1 89  ? -14.739 29.491  -13.083 1.00 25.71  ? 89  ILE D O   1 
ATOM   11040 C  CB  . ILE D 1 89  ? -14.233 27.498  -15.164 1.00 21.97  ? 89  ILE D CB  1 
ATOM   11041 C  CG1 . ILE D 1 89  ? -13.779 26.894  -16.505 1.00 23.11  ? 89  ILE D CG1 1 
ATOM   11042 C  CG2 . ILE D 1 89  ? -15.150 26.552  -14.431 1.00 24.80  ? 89  ILE D CG2 1 
ATOM   11043 C  CD1 . ILE D 1 89  ? -12.834 25.714  -16.377 1.00 25.20  ? 89  ILE D CD1 1 
ATOM   11044 N  N   . ILE D 1 90  ? -16.789 29.682  -14.008 1.00 29.91  ? 90  ILE D N   1 
ATOM   11045 C  CA  . ILE D 1 90  ? -17.426 30.340  -12.871 1.00 31.33  ? 90  ILE D CA  1 
ATOM   11046 C  C   . ILE D 1 90  ? -18.119 29.274  -12.036 1.00 32.82  ? 90  ILE D C   1 
ATOM   11047 O  O   . ILE D 1 90  ? -18.995 28.560  -12.537 1.00 32.15  ? 90  ILE D O   1 
ATOM   11048 C  CB  . ILE D 1 90  ? -18.440 31.401  -13.330 1.00 31.09  ? 90  ILE D CB  1 
ATOM   11049 C  CG1 . ILE D 1 90  ? -17.807 32.357  -14.343 1.00 29.23  ? 90  ILE D CG1 1 
ATOM   11050 C  CG2 . ILE D 1 90  ? -18.950 32.209  -12.123 1.00 32.39  ? 90  ILE D CG2 1 
ATOM   11051 C  CD1 . ILE D 1 90  ? -16.724 33.187  -13.737 1.00 24.10  ? 90  ILE D CD1 1 
ATOM   11052 N  N   . PHE D 1 91  ? -17.749 29.160  -10.769 1.00 31.02  ? 91  PHE D N   1 
ATOM   11053 C  CA  . PHE D 1 91  ? -18.373 28.180  -9.885  1.00 33.58  ? 91  PHE D CA  1 
ATOM   11054 C  C   . PHE D 1 91  ? -19.332 28.881  -8.936  1.00 30.41  ? 91  PHE D C   1 
ATOM   11055 O  O   . PHE D 1 91  ? -18.963 29.871  -8.287  1.00 35.67  ? 91  PHE D O   1 
ATOM   11056 C  CB  . PHE D 1 91  ? -17.322 27.394  -9.103  1.00 31.99  ? 91  PHE D CB  1 
ATOM   11057 C  CG  . PHE D 1 91  ? -17.892 26.589  -7.967  1.00 33.51  ? 91  PHE D CG  1 
ATOM   11058 C  CD1 . PHE D 1 91  ? -18.449 25.356  -8.201  1.00 29.96  ? 91  PHE D CD1 1 
ATOM   11059 C  CD2 . PHE D 1 91  ? -17.856 27.069  -6.670  1.00 31.96  ? 91  PHE D CD2 1 
ATOM   11060 C  CE1 . PHE D 1 91  ? -18.973 24.604  -7.159  1.00 36.58  ? 91  PHE D CE1 1 
ATOM   11061 C  CE2 . PHE D 1 91  ? -18.377 26.329  -5.637  1.00 35.03  ? 91  PHE D CE2 1 
ATOM   11062 C  CZ  . PHE D 1 91  ? -18.930 25.090  -5.883  1.00 31.90  ? 91  PHE D CZ  1 
ATOM   11063 N  N   . VAL D 1 92  ? -20.559 28.374  -8.850  1.00 35.71  ? 92  VAL D N   1 
ATOM   11064 C  CA  . VAL D 1 92  ? -21.557 28.967  -7.967  1.00 36.62  ? 92  VAL D CA  1 
ATOM   11065 C  C   . VAL D 1 92  ? -21.829 27.991  -6.821  1.00 36.52  ? 92  VAL D C   1 
ATOM   11066 O  O   . VAL D 1 92  ? -22.405 26.907  -7.042  1.00 32.59  ? 92  VAL D O   1 
ATOM   11067 C  CB  . VAL D 1 92  ? -22.851 29.327  -8.706  1.00 33.09  ? 92  VAL D CB  1 
ATOM   11068 C  CG1 . VAL D 1 92  ? -23.832 29.953  -7.714  1.00 38.34  ? 92  VAL D CG1 1 
ATOM   11069 C  CG2 . VAL D 1 92  ? -22.564 30.293  -9.833  1.00 33.43  ? 92  VAL D CG2 1 
ATOM   11070 N  N   . PRO D 1 93  ? -21.443 28.337  -5.580  1.00 37.02  ? 93  PRO D N   1 
ATOM   11071 C  CA  . PRO D 1 93  ? -21.670 27.445  -4.433  1.00 33.65  ? 93  PRO D CA  1 
ATOM   11072 C  C   . PRO D 1 93  ? -23.144 27.314  -4.090  1.00 39.02  ? 93  PRO D C   1 
ATOM   11073 O  O   . PRO D 1 93  ? -23.737 28.259  -3.564  1.00 43.90  ? 93  PRO D O   1 
ATOM   11074 C  CB  . PRO D 1 93  ? -20.911 28.135  -3.293  1.00 36.81  ? 93  PRO D CB  1 
ATOM   11075 C  CG  . PRO D 1 93  ? -20.068 29.175  -3.940  1.00 40.22  ? 93  PRO D CG  1 
ATOM   11076 C  CD  . PRO D 1 93  ? -20.786 29.589  -5.175  1.00 39.96  ? 93  PRO D CD  1 
ATOM   11077 N  N   . LEU D 1 94  ? -23.738 26.154  -4.383  1.00 37.08  ? 94  LEU D N   1 
ATOM   11078 C  CA  . LEU D 1 94  ? -25.138 25.876  -4.055  1.00 40.07  ? 94  LEU D CA  1 
ATOM   11079 C  C   . LEU D 1 94  ? -25.253 24.383  -3.780  1.00 37.99  ? 94  LEU D C   1 
ATOM   11080 O  O   . LEU D 1 94  ? -25.294 23.573  -4.716  1.00 39.36  ? 94  LEU D O   1 
ATOM   11081 C  CB  . LEU D 1 94  ? -26.076 26.298  -5.181  1.00 39.54  ? 94  LEU D CB  1 
ATOM   11082 C  CG  . LEU D 1 94  ? -27.524 25.810  -5.132  1.00 43.93  ? 94  LEU D CG  1 
ATOM   11083 C  CD1 . LEU D 1 94  ? -28.292 26.494  -4.020  1.00 38.59  ? 94  LEU D CD1 1 
ATOM   11084 C  CD2 . LEU D 1 94  ? -28.199 26.023  -6.492  1.00 44.59  ? 94  LEU D CD2 1 
ATOM   11085 N  N   . PRO D 1 95  ? -25.308 23.976  -2.513  1.00 41.37  ? 95  PRO D N   1 
ATOM   11086 C  CA  . PRO D 1 95  ? -25.285 22.534  -2.205  1.00 38.03  ? 95  PRO D CA  1 
ATOM   11087 C  C   . PRO D 1 95  ? -26.483 21.805  -2.811  1.00 38.05  ? 95  PRO D C   1 
ATOM   11088 O  O   . PRO D 1 95  ? -27.614 22.299  -2.792  1.00 30.46  ? 95  PRO D O   1 
ATOM   11089 C  CB  . PRO D 1 95  ? -25.313 22.489  -0.667  1.00 41.74  ? 95  PRO D CB  1 
ATOM   11090 C  CG  . PRO D 1 95  ? -25.062 23.913  -0.195  1.00 41.65  ? 95  PRO D CG  1 
ATOM   11091 C  CD  . PRO D 1 95  ? -25.534 24.809  -1.317  1.00 44.92  ? 95  PRO D CD  1 
ATOM   11092 N  N   . GLY D 1 96  ? -26.217 20.621  -3.375  1.00 28.86  ? 96  GLY D N   1 
ATOM   11093 C  CA  . GLY D 1 96  ? -27.238 19.839  -4.033  1.00 33.89  ? 96  GLY D CA  1 
ATOM   11094 C  C   . GLY D 1 96  ? -27.504 20.209  -5.477  1.00 43.07  ? 96  GLY D C   1 
ATOM   11095 O  O   . GLY D 1 96  ? -28.106 19.408  -6.203  1.00 37.38  ? 96  GLY D O   1 
ATOM   11096 N  N   . GLY D 1 97  ? -27.081 21.401  -5.913  1.00 39.97  ? 97  GLY D N   1 
ATOM   11097 C  CA  . GLY D 1 97  ? -27.155 21.823  -7.294  1.00 37.37  ? 97  GLY D CA  1 
ATOM   11098 C  C   . GLY D 1 97  ? -28.560 22.152  -7.765  1.00 40.06  ? 97  GLY D C   1 
ATOM   11099 O  O   . GLY D 1 97  ? -29.485 22.399  -6.991  1.00 40.48  ? 97  GLY D O   1 
ATOM   11100 N  N   . LEU D 1 98  ? -28.700 22.143  -9.083  1.00 46.32  ? 98  LEU D N   1 
ATOM   11101 C  CA  . LEU D 1 98  ? -29.742 22.450  -10.049 1.00 38.73  ? 98  LEU D CA  1 
ATOM   11102 C  C   . LEU D 1 98  ? -30.393 21.184  -10.573 1.00 35.13  ? 98  LEU D C   1 
ATOM   11103 O  O   . LEU D 1 98  ? -29.704 20.189  -10.849 1.00 34.51  ? 98  LEU D O   1 
ATOM   11104 C  CB  . LEU D 1 98  ? -29.166 23.234  -11.234 1.00 40.51  ? 98  LEU D CB  1 
ATOM   11105 C  CG  . LEU D 1 98  ? -28.701 24.635  -10.881 1.00 34.07  ? 98  LEU D CG  1 
ATOM   11106 C  CD1 . LEU D 1 98  ? -28.058 25.357  -12.062 1.00 37.78  ? 98  LEU D CD1 1 
ATOM   11107 C  CD2 . LEU D 1 98  ? -29.906 25.374  -10.382 1.00 40.43  ? 98  LEU D CD2 1 
ATOM   11108 N  N   . PRO D 1 99  ? -31.711 21.211  -10.733 1.00 38.38  ? 99  PRO D N   1 
ATOM   11109 C  CA  . PRO D 1 99  ? -32.378 20.138  -11.468 1.00 36.36  ? 99  PRO D CA  1 
ATOM   11110 C  C   . PRO D 1 99  ? -31.970 20.191  -12.928 1.00 36.19  ? 99  PRO D C   1 
ATOM   11111 O  O   . PRO D 1 99  ? -31.515 21.218  -13.436 1.00 34.65  ? 99  PRO D O   1 
ATOM   11112 C  CB  . PRO D 1 99  ? -33.859 20.474  -11.308 1.00 34.21  ? 99  PRO D CB  1 
ATOM   11113 C  CG  . PRO D 1 99  ? -33.865 21.970  -11.235 1.00 32.33  ? 99  PRO D CG  1 
ATOM   11114 C  CD  . PRO D 1 99  ? -32.626 22.328  -10.437 1.00 38.58  ? 99  PRO D CD  1 
ATOM   11115 N  N   . ASP D 1 100 ? -32.152 19.069  -13.610 1.00 34.63  ? 100 ASP D N   1 
ATOM   11116 C  CA  . ASP D 1 100 ? -31.992 19.073  -15.053 1.00 35.96  ? 100 ASP D CA  1 
ATOM   11117 C  C   . ASP D 1 100 ? -32.964 20.060  -15.682 1.00 39.26  ? 100 ASP D C   1 
ATOM   11118 O  O   . ASP D 1 100 ? -34.011 20.380  -15.120 1.00 37.59  ? 100 ASP D O   1 
ATOM   11119 C  CB  . ASP D 1 100 ? -32.231 17.677  -15.602 1.00 40.04  ? 100 ASP D CB  1 
ATOM   11120 C  CG  . ASP D 1 100 ? -31.070 16.778  -15.344 1.00 43.41  ? 100 ASP D CG  1 
ATOM   11121 O  OD1 . ASP D 1 100 ? -29.927 17.320  -15.313 1.00 38.49  ? 100 ASP D OD1 1 
ATOM   11122 O  OD2 . ASP D 1 100 ? -31.298 15.560  -15.134 1.00 38.38  ? 100 ASP D OD2 1 
ATOM   11123 N  N   . GLY D 1 101 ? -32.609 20.558  -16.856 1.00 39.13  ? 101 GLY D N   1 
ATOM   11124 C  CA  . GLY D 1 101 ? -33.536 21.420  -17.546 1.00 33.85  ? 101 GLY D CA  1 
ATOM   11125 C  C   . GLY D 1 101 ? -32.835 22.624  -18.117 1.00 37.27  ? 101 GLY D C   1 
ATOM   11126 O  O   . GLY D 1 101 ? -31.609 22.720  -18.045 1.00 37.98  ? 101 GLY D O   1 
ATOM   11127 N  N   . VAL D 1 102 ? -33.595 23.529  -18.699 1.00 34.08  ? 102 VAL D N   1 
ATOM   11128 C  CA  . VAL D 1 102 ? -33.068 24.783  -19.210 1.00 35.20  ? 102 VAL D CA  1 
ATOM   11129 C  C   . VAL D 1 102 ? -33.238 25.831  -18.128 1.00 37.21  ? 102 VAL D C   1 
ATOM   11130 O  O   . VAL D 1 102 ? -34.244 25.841  -17.415 1.00 45.10  ? 102 VAL D O   1 
ATOM   11131 C  CB  . VAL D 1 102 ? -33.802 25.183  -20.495 1.00 37.51  ? 102 VAL D CB  1 
ATOM   11132 C  CG1 . VAL D 1 102 ? -33.066 26.323  -21.192 1.00 31.36  ? 102 VAL D CG1 1 
ATOM   11133 C  CG2 . VAL D 1 102 ? -33.965 23.966  -21.388 1.00 33.61  ? 102 VAL D CG2 1 
ATOM   11134 N  N   . HIS D 1 103 ? -32.253 26.703  -17.976 1.00 41.43  ? 103 HIS D N   1 
ATOM   11135 C  CA  . HIS D 1 103 ? -32.299 27.712  -16.929 1.00 40.26  ? 103 HIS D CA  1 
ATOM   11136 C  C   . HIS D 1 103 ? -32.004 29.073  -17.523 1.00 37.19  ? 103 HIS D C   1 
ATOM   11137 O  O   . HIS D 1 103 ? -31.111 29.219  -18.358 1.00 38.64  ? 103 HIS D O   1 
ATOM   11138 C  CB  . HIS D 1 103 ? -31.313 27.398  -15.799 1.00 38.58  ? 103 HIS D CB  1 
ATOM   11139 C  CG  . HIS D 1 103 ? -31.571 26.084  -15.128 1.00 40.83  ? 103 HIS D CG  1 
ATOM   11140 N  ND1 . HIS D 1 103 ? -32.677 25.857  -14.336 1.00 45.86  ? 103 HIS D ND1 1 
ATOM   11141 C  CD2 . HIS D 1 103 ? -30.870 24.923  -15.135 1.00 42.30  ? 103 HIS D CD2 1 
ATOM   11142 C  CE1 . HIS D 1 103 ? -32.647 24.613  -13.886 1.00 42.00  ? 103 HIS D CE1 1 
ATOM   11143 N  NE2 . HIS D 1 103 ? -31.562 24.024  -14.359 1.00 40.39  ? 103 HIS D NE2 1 
ATOM   11144 N  N   . GLU D 1 104 ? -32.759 30.067  -17.075 1.00 38.85  ? 104 GLU D N   1 
ATOM   11145 C  CA  . GLU D 1 104 ? -32.593 31.441  -17.528 1.00 40.14  ? 104 GLU D CA  1 
ATOM   11146 C  C   . GLU D 1 104 ? -31.494 32.114  -16.709 1.00 43.22  ? 104 GLU D C   1 
ATOM   11147 O  O   . GLU D 1 104 ? -31.733 32.941  -15.828 1.00 48.04  ? 104 GLU D O   1 
ATOM   11148 C  CB  . GLU D 1 104 ? -33.918 32.180  -17.429 1.00 47.29  ? 104 GLU D CB  1 
ATOM   11149 C  CG  . GLU D 1 104 ? -33.968 33.524  -18.091 1.00 46.53  ? 104 GLU D CG  1 
ATOM   11150 C  CD  . GLU D 1 104 ? -34.918 34.444  -17.375 1.00 55.67  ? 104 GLU D CD  1 
ATOM   11151 O  OE1 . GLU D 1 104 ? -36.141 34.230  -17.513 1.00 62.37  ? 104 GLU D OE1 1 
ATOM   11152 O  OE2 . GLU D 1 104 ? -34.449 35.380  -16.684 1.00 59.36  ? 104 GLU D OE2 1 
ATOM   11153 N  N   . LEU D 1 105 ? -30.260 31.733  -17.032 1.00 41.05  ? 105 LEU D N   1 
ATOM   11154 C  CA  . LEU D 1 105 ? -29.081 32.279  -16.374 1.00 36.41  ? 105 LEU D CA  1 
ATOM   11155 C  C   . LEU D 1 105 ? -28.847 33.724  -16.791 1.00 38.43  ? 105 LEU D C   1 
ATOM   11156 O  O   . LEU D 1 105 ? -28.880 34.049  -17.979 1.00 41.14  ? 105 LEU D O   1 
ATOM   11157 C  CB  . LEU D 1 105 ? -27.864 31.427  -16.725 1.00 39.17  ? 105 LEU D CB  1 
ATOM   11158 C  CG  . LEU D 1 105 ? -26.547 31.643  -15.985 1.00 37.33  ? 105 LEU D CG  1 
ATOM   11159 C  CD1 . LEU D 1 105 ? -26.786 31.630  -14.497 1.00 38.03  ? 105 LEU D CD1 1 
ATOM   11160 C  CD2 . LEU D 1 105 ? -25.516 30.572  -16.375 1.00 29.03  ? 105 LEU D CD2 1 
ATOM   11161 N  N   . SER D 1 106 ? -28.602 34.590  -15.810 1.00 35.83  ? 106 SER D N   1 
ATOM   11162 C  CA  . SER D 1 106 ? -28.340 36.001  -16.034 1.00 39.94  ? 106 SER D CA  1 
ATOM   11163 C  C   . SER D 1 106 ? -27.084 36.383  -15.273 1.00 36.56  ? 106 SER D C   1 
ATOM   11164 O  O   . SER D 1 106 ? -26.966 36.086  -14.082 1.00 38.26  ? 106 SER D O   1 
ATOM   11165 C  CB  . SER D 1 106 ? -29.516 36.863  -15.576 1.00 41.51  ? 106 SER D CB  1 
ATOM   11166 O  OG  . SER D 1 106 ? -30.702 36.467  -16.241 1.00 47.52  ? 106 SER D OG  1 
ATOM   11167 N  N   . ILE D 1 107 ? -26.144 37.035  -15.954 1.00 31.43  ? 107 ILE D N   1 
ATOM   11168 C  CA  . ILE D 1 107 ? -24.867 37.350  -15.334 1.00 34.40  ? 107 ILE D CA  1 
ATOM   11169 C  C   . ILE D 1 107 ? -24.677 38.858  -15.349 1.00 35.10  ? 107 ILE D C   1 
ATOM   11170 O  O   . ILE D 1 107 ? -25.265 39.574  -16.162 1.00 36.16  ? 107 ILE D O   1 
ATOM   11171 C  CB  . ILE D 1 107 ? -23.691 36.623  -16.027 1.00 34.31  ? 107 ILE D CB  1 
ATOM   11172 C  CG1 . ILE D 1 107 ? -23.696 36.879  -17.535 1.00 38.74  ? 107 ILE D CG1 1 
ATOM   11173 C  CG2 . ILE D 1 107 ? -23.773 35.133  -15.767 1.00 30.10  ? 107 ILE D CG2 1 
ATOM   11174 C  CD1 . ILE D 1 107 ? -22.702 37.906  -17.985 1.00 35.26  ? 107 ILE D CD1 1 
ATOM   11175 N  N   . GLU D 1 108 ? -23.851 39.346  -14.424 1.00 36.19  ? 108 GLU D N   1 
ATOM   11176 C  CA  . GLU D 1 108 ? -23.420 40.745  -14.449 1.00 38.16  ? 108 GLU D CA  1 
ATOM   11177 C  C   . GLU D 1 108 ? -21.907 40.759  -14.270 1.00 35.26  ? 108 GLU D C   1 
ATOM   11178 O  O   . GLU D 1 108 ? -21.395 40.837  -13.153 1.00 39.98  ? 108 GLU D O   1 
ATOM   11179 C  CB  . GLU D 1 108 ? -24.132 41.587  -13.389 1.00 42.59  ? 108 GLU D CB  1 
ATOM   11180 C  CG  . GLU D 1 108 ? -23.675 43.041  -13.397 1.00 48.39  ? 108 GLU D CG  1 
ATOM   11181 C  CD  . GLU D 1 108 ? -23.981 43.763  -12.106 1.00 54.94  ? 108 GLU D CD  1 
ATOM   11182 O  OE1 . GLU D 1 108 ? -25.063 43.514  -11.525 1.00 61.09  ? 108 GLU D OE1 1 
ATOM   11183 O  OE2 . GLU D 1 108 ? -23.139 44.583  -11.677 1.00 54.93  ? 108 GLU D OE2 1 
ATOM   11184 N  N   . LEU D 1 109 ? -21.189 40.673  -15.381 1.00 39.13  ? 109 LEU D N   1 
ATOM   11185 C  CA  . LEU D 1 109 ? -19.734 40.670  -15.362 1.00 34.23  ? 109 LEU D CA  1 
ATOM   11186 C  C   . LEU D 1 109 ? -19.214 42.086  -15.211 1.00 34.43  ? 109 LEU D C   1 
ATOM   11187 O  O   . LEU D 1 109 ? -19.688 42.993  -15.892 1.00 39.06  ? 109 LEU D O   1 
ATOM   11188 C  CB  . LEU D 1 109 ? -19.201 40.063  -16.654 1.00 32.03  ? 109 LEU D CB  1 
ATOM   11189 C  CG  . LEU D 1 109 ? -17.695 40.072  -16.822 1.00 32.39  ? 109 LEU D CG  1 
ATOM   11190 C  CD1 . LEU D 1 109 ? -17.055 39.277  -15.702 1.00 29.95  ? 109 LEU D CD1 1 
ATOM   11191 C  CD2 . LEU D 1 109 ? -17.412 39.424  -18.157 1.00 35.64  ? 109 LEU D CD2 1 
ATOM   11192 N  N   . ARG D 1 110 ? -18.235 42.280  -14.330 1.00 29.43  ? 110 ARG D N   1 
ATOM   11193 C  CA  . ARG D 1 110 ? -17.616 43.583  -14.140 1.00 34.80  ? 110 ARG D CA  1 
ATOM   11194 C  C   . ARG D 1 110 ? -16.118 43.444  -14.349 1.00 34.83  ? 110 ARG D C   1 
ATOM   11195 O  O   . ARG D 1 110 ? -15.502 42.532  -13.787 1.00 33.81  ? 110 ARG D O   1 
ATOM   11196 C  CB  . ARG D 1 110 ? -17.924 44.145  -12.745 1.00 38.75  ? 110 ARG D CB  1 
ATOM   11197 C  CG  . ARG D 1 110 ? -19.405 44.220  -12.435 1.00 39.60  ? 110 ARG D CG  1 
ATOM   11198 C  CD  . ARG D 1 110 ? -19.650 44.511  -10.965 1.00 48.18  ? 110 ARG D CD  1 
ATOM   11199 N  NE  . ARG D 1 110 ? -20.166 45.858  -10.761 1.00 48.18  ? 110 ARG D NE  1 
ATOM   11200 C  CZ  . ARG D 1 110 ? -20.287 46.443  -9.578  1.00 54.92  ? 110 ARG D CZ  1 
ATOM   11201 N  NH1 . ARG D 1 110 ? -19.939 45.825  -8.460  1.00 53.54  ? 110 ARG D NH1 1 
ATOM   11202 N  NH2 . ARG D 1 110 ? -20.781 47.676  -9.512  1.00 59.59  ? 110 ARG D NH2 1 
ATOM   11203 N  N   . LEU D 1 111 ? -15.550 44.338  -15.166 1.00 30.12  ? 111 LEU D N   1 
ATOM   11204 C  CA  . LEU D 1 111 ? -14.138 44.360  -15.527 1.00 31.17  ? 111 LEU D CA  1 
ATOM   11205 C  C   . LEU D 1 111 ? -13.614 45.789  -15.436 1.00 34.47  ? 111 LEU D C   1 
ATOM   11206 O  O   . LEU D 1 111 ? -14.323 46.739  -15.774 1.00 36.76  ? 111 LEU D O   1 
ATOM   11207 C  CB  . LEU D 1 111 ? -13.896 43.860  -16.968 1.00 38.03  ? 111 LEU D CB  1 
ATOM   11208 C  CG  . LEU D 1 111 ? -14.378 42.514  -17.506 1.00 34.89  ? 111 LEU D CG  1 
ATOM   11209 C  CD1 . LEU D 1 111 ? -13.808 42.312  -18.925 1.00 33.84  ? 111 LEU D CD1 1 
ATOM   11210 C  CD2 . LEU D 1 111 ? -13.950 41.387  -16.593 1.00 30.63  ? 111 LEU D CD2 1 
ATOM   11211 N  N   . ARG D 1 112 ? -12.355 45.937  -15.021 1.00 32.92  ? 112 ARG D N   1 
ATOM   11212 C  CA  . ARG D 1 112 ? -11.733 47.246  -14.836 1.00 33.17  ? 112 ARG D CA  1 
ATOM   11213 C  C   . ARG D 1 112 ? -10.791 47.553  -15.998 1.00 37.28  ? 112 ARG D C   1 
ATOM   11214 O  O   . ARG D 1 112 ? -9.811  46.828  -16.220 1.00 34.23  ? 112 ARG D O   1 
ATOM   11215 C  CB  . ARG D 1 112 ? -10.957 47.326  -13.518 1.00 31.68  ? 112 ARG D CB  1 
ATOM   11216 C  CG  . ARG D 1 112 ? -11.810 47.341  -12.261 1.00 36.78  ? 112 ARG D CG  1 
ATOM   11217 C  CD  . ARG D 1 112 ? -10.976 47.643  -11.018 1.00 26.22  ? 112 ARG D CD  1 
ATOM   11218 N  NE  . ARG D 1 112 ? -10.363 46.427  -10.496 1.00 37.75  ? 112 ARG D NE  1 
ATOM   11219 C  CZ  . ARG D 1 112 ? -9.062  46.191  -10.538 1.00 37.26  ? 112 ARG D CZ  1 
ATOM   11220 N  NH1 . ARG D 1 112 ? -8.215  47.093  -11.008 1.00 31.03  ? 112 ARG D NH1 1 
ATOM   11221 N  NH2 . ARG D 1 112 ? -8.595  45.039  -10.067 1.00 33.09  ? 112 ARG D NH2 1 
ATOM   11222 N  N   . MET D 1 113 ? -11.063 48.654  -16.701 1.00 30.52  ? 113 MET D N   1 
ATOM   11223 C  CA  . MET D 1 113 ? -10.245 49.118  -17.813 1.00 35.80  ? 113 MET D CA  1 
ATOM   11224 C  C   . MET D 1 113 ? -9.574  50.410  -17.377 1.00 37.32  ? 113 MET D C   1 
ATOM   11225 O  O   . MET D 1 113 ? -10.225 51.460  -17.311 1.00 36.87  ? 113 MET D O   1 
ATOM   11226 C  CB  . MET D 1 113 ? -11.080 49.359  -19.067 1.00 39.88  ? 113 MET D CB  1 
ATOM   11227 C  CG  . MET D 1 113 ? -12.287 48.438  -19.244 1.00 40.09  ? 113 MET D CG  1 
ATOM   11228 S  SD  . MET D 1 113 ? -11.842 46.728  -19.211 1.00 45.81  ? 113 MET D SD  1 
ATOM   11229 C  CE  . MET D 1 113 ? -13.161 45.965  -20.148 1.00 34.87  ? 113 MET D CE  1 
ATOM   11230 N  N   . SER D 1 114 ? -8.274  50.338  -17.097 1.00 34.77  ? 114 SER D N   1 
ATOM   11231 C  CA  . SER D 1 114 ? -7.560  51.512  -16.614 1.00 34.70  ? 114 SER D CA  1 
ATOM   11232 C  C   . SER D 1 114 ? -7.520  52.633  -17.642 1.00 38.20  ? 114 SER D C   1 
ATOM   11233 O  O   . SER D 1 114 ? -7.247  53.781  -17.271 1.00 40.54  ? 114 SER D O   1 
ATOM   11234 C  CB  . SER D 1 114 ? -6.135  51.134  -16.207 1.00 36.80  ? 114 SER D CB  1 
ATOM   11235 O  OG  . SER D 1 114 ? -6.108  49.865  -15.560 1.00 32.15  ? 114 SER D OG  1 
ATOM   11236 N  N   . TYR D 1 115 ? -7.762  52.338  -18.921 1.00 32.26  ? 115 TYR D N   1 
ATOM   11237 C  CA  . TYR D 1 115 ? -7.749  53.386  -19.934 1.00 35.81  ? 115 TYR D CA  1 
ATOM   11238 C  C   . TYR D 1 115 ? -9.114  54.038  -20.113 1.00 35.50  ? 115 TYR D C   1 
ATOM   11239 O  O   . TYR D 1 115 ? -9.249  54.965  -20.913 1.00 39.08  ? 115 TYR D O   1 
ATOM   11240 C  CB  . TYR D 1 115 ? -7.254  52.833  -21.282 1.00 40.97  ? 115 TYR D CB  1 
ATOM   11241 C  CG  . TYR D 1 115 ? -7.992  51.599  -21.725 1.00 36.26  ? 115 TYR D CG  1 
ATOM   11242 C  CD1 . TYR D 1 115 ? -7.553  50.335  -21.364 1.00 34.23  ? 115 TYR D CD1 1 
ATOM   11243 C  CD2 . TYR D 1 115 ? -9.159  51.702  -22.471 1.00 37.70  ? 115 TYR D CD2 1 
ATOM   11244 C  CE1 . TYR D 1 115 ? -8.254  49.198  -21.752 1.00 38.92  ? 115 TYR D CE1 1 
ATOM   11245 C  CE2 . TYR D 1 115 ? -9.864  50.574  -22.863 1.00 36.86  ? 115 TYR D CE2 1 
ATOM   11246 C  CZ  . TYR D 1 115 ? -9.403  49.323  -22.501 1.00 36.06  ? 115 TYR D CZ  1 
ATOM   11247 O  OH  . TYR D 1 115 ? -10.102 48.203  -22.900 1.00 37.41  ? 115 TYR D OH  1 
ATOM   11248 N  N   . ILE D 1 116 ? -10.128 53.591  -19.389 1.00 37.55  ? 116 ILE D N   1 
ATOM   11249 C  CA  . ILE D 1 116 ? -11.406 54.291  -19.405 1.00 39.14  ? 116 ILE D CA  1 
ATOM   11250 C  C   . ILE D 1 116 ? -11.502 55.205  -18.183 1.00 41.46  ? 116 ILE D C   1 
ATOM   11251 O  O   . ILE D 1 116 ? -11.010 54.851  -17.100 1.00 38.37  ? 116 ILE D O   1 
ATOM   11252 C  CB  . ILE D 1 116 ? -12.560 53.287  -19.488 1.00 36.34  ? 116 ILE D CB  1 
ATOM   11253 C  CG1 . ILE D 1 116 ? -12.412 52.506  -20.786 1.00 37.55  ? 116 ILE D CG1 1 
ATOM   11254 C  CG2 . ILE D 1 116 ? -13.900 53.991  -19.447 1.00 34.49  ? 116 ILE D CG2 1 
ATOM   11255 C  CD1 . ILE D 1 116 ? -13.326 51.368  -20.922 1.00 29.59  ? 116 ILE D CD1 1 
ATOM   11256 N  N   . PRO D 1 117 ? -12.073 56.406  -18.320 1.00 41.50  ? 117 PRO D N   1 
ATOM   11257 C  CA  . PRO D 1 117 ? -12.242 57.276  -17.149 1.00 42.64  ? 117 PRO D CA  1 
ATOM   11258 C  C   . PRO D 1 117 ? -13.125 56.630  -16.088 1.00 44.88  ? 117 PRO D C   1 
ATOM   11259 O  O   . PRO D 1 117 ? -14.100 55.937  -16.391 1.00 40.59  ? 117 PRO D O   1 
ATOM   11260 C  CB  . PRO D 1 117 ? -12.884 58.537  -17.738 1.00 45.77  ? 117 PRO D CB  1 
ATOM   11261 C  CG  . PRO D 1 117 ? -12.463 58.533  -19.175 1.00 45.87  ? 117 PRO D CG  1 
ATOM   11262 C  CD  . PRO D 1 117 ? -12.438 57.092  -19.573 1.00 42.35  ? 117 PRO D CD  1 
ATOM   11263 N  N   . GLN D 1 118 ? -12.778 56.892  -14.827 1.00 41.52  ? 118 GLN D N   1 
ATOM   11264 C  CA  . GLN D 1 118 ? -13.341 56.135  -13.711 1.00 47.23  ? 118 GLN D CA  1 
ATOM   11265 C  C   . GLN D 1 118 ? -14.841 56.379  -13.536 1.00 49.65  ? 118 GLN D C   1 
ATOM   11266 O  O   . GLN D 1 118 ? -15.562 55.486  -13.072 1.00 43.33  ? 118 GLN D O   1 
ATOM   11267 C  CB  . GLN D 1 118 ? -12.545 56.476  -12.448 1.00 50.55  ? 118 GLN D CB  1 
ATOM   11268 C  CG  . GLN D 1 118 ? -13.203 56.205  -11.111 1.00 59.72  ? 118 GLN D CG  1 
ATOM   11269 C  CD  . GLN D 1 118 ? -12.553 57.025  -10.004 1.00 55.15  ? 118 GLN D CD  1 
ATOM   11270 O  OE1 . GLN D 1 118 ? -13.205 57.837  -9.345  1.00 56.29  ? 118 GLN D OE1 1 
ATOM   11271 N  NE2 . GLN D 1 118 ? -11.255 56.820  -9.806  1.00 54.52  ? 118 GLN D NE2 1 
ATOM   11272 N  N   . GLU D 1 119 ? -15.336 57.560  -13.924 1.00 49.94  ? 119 GLU D N   1 
ATOM   11273 C  CA  . GLU D 1 119 ? -16.775 57.821  -13.921 1.00 49.31  ? 119 GLU D CA  1 
ATOM   11274 C  C   . GLU D 1 119 ? -17.524 57.004  -14.967 1.00 49.64  ? 119 GLU D C   1 
ATOM   11275 O  O   . GLU D 1 119 ? -18.758 57.079  -15.025 1.00 55.21  ? 119 GLU D O   1 
ATOM   11276 C  CB  . GLU D 1 119 ? -17.052 59.313  -14.139 1.00 47.80  ? 119 GLU D CB  1 
ATOM   11277 C  CG  . GLU D 1 119 ? -16.211 59.960  -15.237 1.00 49.77  ? 119 GLU D CG  1 
ATOM   11278 C  CD  . GLU D 1 119 ? -14.867 60.496  -14.736 1.00 50.39  ? 119 GLU D CD  1 
ATOM   11279 O  OE1 . GLU D 1 119 ? -13.835 60.236  -15.389 1.00 50.83  ? 119 GLU D OE1 1 
ATOM   11280 O  OE2 . GLU D 1 119 ? -14.838 61.195  -13.702 1.00 44.22  ? 119 GLU D OE2 1 
ATOM   11281 N  N   . HIS D 1 120 ? -16.812 56.241  -15.797 1.00 43.50  ? 120 HIS D N   1 
ATOM   11282 C  CA  . HIS D 1 120 ? -17.417 55.316  -16.747 1.00 41.38  ? 120 HIS D CA  1 
ATOM   11283 C  C   . HIS D 1 120 ? -17.015 53.874  -16.454 1.00 46.48  ? 120 HIS D C   1 
ATOM   11284 O  O   . HIS D 1 120 ? -17.034 53.028  -17.357 1.00 43.26  ? 120 HIS D O   1 
ATOM   11285 C  CB  . HIS D 1 120 ? -17.033 55.708  -18.175 1.00 39.96  ? 120 HIS D CB  1 
ATOM   11286 C  CG  . HIS D 1 120 ? -17.768 56.906  -18.684 1.00 40.84  ? 120 HIS D CG  1 
ATOM   11287 N  ND1 . HIS D 1 120 ? -17.143 57.932  -19.361 1.00 43.99  ? 120 HIS D ND1 1 
ATOM   11288 C  CD2 . HIS D 1 120 ? -19.075 57.247  -18.604 1.00 39.99  ? 120 HIS D CD2 1 
ATOM   11289 C  CE1 . HIS D 1 120 ? -18.036 58.848  -19.689 1.00 42.82  ? 120 HIS D CE1 1 
ATOM   11290 N  NE2 . HIS D 1 120 ? -19.216 58.457  -19.239 1.00 48.19  ? 120 HIS D NE2 1 
ATOM   11291 N  N   . GLN D 1 121 ? -16.657 53.578  -15.205 1.00 45.47  ? 121 GLN D N   1 
ATOM   11292 C  CA  . GLN D 1 121 ? -16.089 52.297  -14.814 1.00 37.68  ? 121 GLN D CA  1 
ATOM   11293 C  C   . GLN D 1 121 ? -16.688 51.850  -13.491 1.00 44.68  ? 121 GLN D C   1 
ATOM   11294 O  O   . GLN D 1 121 ? -17.096 52.689  -12.677 1.00 49.00  ? 121 GLN D O   1 
ATOM   11295 C  CB  . GLN D 1 121 ? -14.561 52.374  -14.683 1.00 36.62  ? 121 GLN D CB  1 
ATOM   11296 C  CG  . GLN D 1 121 ? -13.839 52.473  -15.993 1.00 39.45  ? 121 GLN D CG  1 
ATOM   11297 C  CD  . GLN D 1 121 ? -13.762 51.141  -16.693 1.00 41.30  ? 121 GLN D CD  1 
ATOM   11298 O  OE1 . GLN D 1 121 ? -12.999 50.269  -16.284 1.00 42.73  ? 121 GLN D OE1 1 
ATOM   11299 N  NE2 . GLN D 1 121 ? -14.539 50.977  -17.766 1.00 38.33  ? 121 GLN D NE2 1 
ATOM   11300 N  N   . PRO D 1 122 ? -16.739 50.528  -13.236 1.00 44.96  ? 122 PRO D N   1 
ATOM   11301 C  CA  . PRO D 1 122 ? -16.236 49.453  -14.105 1.00 36.97  ? 122 PRO D CA  1 
ATOM   11302 C  C   . PRO D 1 122 ? -17.022 49.238  -15.403 1.00 35.65  ? 122 PRO D C   1 
ATOM   11303 O  O   . PRO D 1 122 ? -18.181 49.639  -15.508 1.00 38.73  ? 122 PRO D O   1 
ATOM   11304 C  CB  . PRO D 1 122 ? -16.353 48.212  -13.212 1.00 40.75  ? 122 PRO D CB  1 
ATOM   11305 C  CG  . PRO D 1 122 ? -17.480 48.528  -12.301 1.00 45.38  ? 122 PRO D CG  1 
ATOM   11306 C  CD  . PRO D 1 122 ? -17.307 49.989  -11.985 1.00 40.50  ? 122 PRO D CD  1 
ATOM   11307 N  N   . SER D 1 123 ? -16.381 48.610  -16.390 1.00 37.03  ? 123 SER D N   1 
ATOM   11308 C  CA  . SER D 1 123 ? -17.105 48.105  -17.546 1.00 30.45  ? 123 SER D CA  1 
ATOM   11309 C  C   . SER D 1 123 ? -18.006 46.952  -17.123 1.00 36.51  ? 123 SER D C   1 
ATOM   11310 O  O   . SER D 1 123 ? -17.600 46.080  -16.349 1.00 37.88  ? 123 SER D O   1 
ATOM   11311 C  CB  . SER D 1 123 ? -16.129 47.651  -18.627 1.00 34.18  ? 123 SER D CB  1 
ATOM   11312 O  OG  . SER D 1 123 ? -15.320 48.728  -19.067 1.00 36.89  ? 123 SER D OG  1 
ATOM   11313 N  N   . THR D 1 124 ? -19.240 46.949  -17.614 1.00 32.27  ? 124 THR D N   1 
ATOM   11314 C  CA  . THR D 1 124 ? -20.231 45.988  -17.137 1.00 33.15  ? 124 THR D CA  1 
ATOM   11315 C  C   . THR D 1 124 ? -20.919 45.298  -18.309 1.00 37.40  ? 124 THR D C   1 
ATOM   11316 O  O   . THR D 1 124 ? -21.198 45.924  -19.334 1.00 36.55  ? 124 THR D O   1 
ATOM   11317 C  CB  . THR D 1 124 ? -21.268 46.672  -16.231 1.00 34.53  ? 124 THR D CB  1 
ATOM   11318 O  OG1 . THR D 1 124 ? -20.601 47.257  -15.101 1.00 39.47  ? 124 THR D OG1 1 
ATOM   11319 C  CG2 . THR D 1 124 ? -22.328 45.671  -15.734 1.00 38.71  ? 124 THR D CG2 1 
ATOM   11320 N  N   . TYR D 1 125 ? -21.166 43.998  -18.155 1.00 30.55  ? 125 TYR D N   1 
ATOM   11321 C  CA  . TYR D 1 125 ? -21.828 43.174  -19.158 1.00 33.67  ? 125 TYR D CA  1 
ATOM   11322 C  C   . TYR D 1 125 ? -22.965 42.433  -18.476 1.00 37.78  ? 125 TYR D C   1 
ATOM   11323 O  O   . TYR D 1 125 ? -22.728 41.658  -17.545 1.00 33.70  ? 125 TYR D O   1 
ATOM   11324 C  CB  . TYR D 1 125 ? -20.833 42.196  -19.791 1.00 33.45  ? 125 TYR D CB  1 
ATOM   11325 C  CG  . TYR D 1 125 ? -19.541 42.890  -20.130 1.00 35.18  ? 125 TYR D CG  1 
ATOM   11326 C  CD1 . TYR D 1 125 ? -18.526 42.997  -19.202 1.00 37.24  ? 125 TYR D CD1 1 
ATOM   11327 C  CD2 . TYR D 1 125 ? -19.356 43.482  -21.363 1.00 34.18  ? 125 TYR D CD2 1 
ATOM   11328 C  CE1 . TYR D 1 125 ? -17.355 43.668  -19.501 1.00 35.79  ? 125 TYR D CE1 1 
ATOM   11329 C  CE2 . TYR D 1 125 ? -18.182 44.147  -21.672 1.00 33.13  ? 125 TYR D CE2 1 
ATOM   11330 C  CZ  . TYR D 1 125 ? -17.192 44.237  -20.740 1.00 33.85  ? 125 TYR D CZ  1 
ATOM   11331 O  OH  . TYR D 1 125 ? -16.022 44.899  -21.029 1.00 30.30  ? 125 TYR D OH  1 
ATOM   11332 N  N   . ARG D 1 126 ? -24.196 42.683  -18.919 1.00 39.95  ? 126 ARG D N   1 
ATOM   11333 C  CA  . ARG D 1 126 ? -25.366 41.974  -18.421 1.00 33.27  ? 126 ARG D CA  1 
ATOM   11334 C  C   . ARG D 1 126 ? -25.951 41.212  -19.586 1.00 39.44  ? 126 ARG D C   1 
ATOM   11335 O  O   . ARG D 1 126 ? -26.520 41.813  -20.502 1.00 47.86  ? 126 ARG D O   1 
ATOM   11336 C  CB  . ARG D 1 126 ? -26.409 42.918  -17.832 1.00 38.06  ? 126 ARG D CB  1 
ATOM   11337 C  CG  . ARG D 1 126 ? -25.833 44.042  -17.032 1.00 41.85  ? 126 ARG D CG  1 
ATOM   11338 C  CD  . ARG D 1 126 ? -26.927 44.943  -16.536 1.00 51.85  ? 126 ARG D CD  1 
ATOM   11339 N  NE  . ARG D 1 126 ? -26.860 45.048  -15.086 1.00 60.55  ? 126 ARG D NE  1 
ATOM   11340 C  CZ  . ARG D 1 126 ? -26.172 45.983  -14.450 1.00 57.50  ? 126 ARG D CZ  1 
ATOM   11341 N  NH1 . ARG D 1 126 ? -25.503 46.913  -15.113 1.00 52.49  ? 126 ARG D NH1 1 
ATOM   11342 N  NH2 . ARG D 1 126 ? -26.153 45.982  -13.117 1.00 62.87  ? 126 ARG D NH2 1 
ATOM   11343 N  N   . VAL D 1 127 ? -25.793 39.899  -19.572 1.00 38.62  ? 127 VAL D N   1 
ATOM   11344 C  CA  . VAL D 1 127 ? -26.472 39.068  -20.546 1.00 38.33  ? 127 VAL D CA  1 
ATOM   11345 C  C   . VAL D 1 127 ? -27.226 37.967  -19.817 1.00 40.91  ? 127 VAL D C   1 
ATOM   11346 O  O   . VAL D 1 127 ? -26.876 37.559  -18.702 1.00 40.77  ? 127 VAL D O   1 
ATOM   11347 C  CB  . VAL D 1 127 ? -25.512 38.481  -21.605 1.00 41.42  ? 127 VAL D CB  1 
ATOM   11348 C  CG1 . VAL D 1 127 ? -24.498 39.540  -22.065 1.00 42.19  ? 127 VAL D CG1 1 
ATOM   11349 C  CG2 . VAL D 1 127 ? -24.828 37.246  -21.100 1.00 31.45  ? 127 VAL D CG2 1 
ATOM   11350 N  N   . THR D 1 128 ? -28.295 37.523  -20.461 1.00 35.68  ? 128 THR D N   1 
ATOM   11351 C  CA  . THR D 1 128 ? -29.167 36.460  -20.018 1.00 35.76  ? 128 THR D CA  1 
ATOM   11352 C  C   . THR D 1 128 ? -29.185 35.414  -21.111 1.00 38.77  ? 128 THR D C   1 
ATOM   11353 O  O   . THR D 1 128 ? -29.258 35.756  -22.290 1.00 38.70  ? 128 THR D O   1 
ATOM   11354 C  CB  . THR D 1 128 ? -30.589 36.982  -19.800 1.00 42.71  ? 128 THR D CB  1 
ATOM   11355 O  OG1 . THR D 1 128 ? -30.608 37.922  -18.712 1.00 42.50  ? 128 THR D OG1 1 
ATOM   11356 C  CG2 . THR D 1 128 ? -31.573 35.818  -19.563 1.00 35.75  ? 128 THR D CG2 1 
ATOM   11357 N  N   . LYS D 1 129 ? -29.126 34.147  -20.730 1.00 33.68  ? 129 LYS D N   1 
ATOM   11358 C  CA  . LYS D 1 129 ? -29.261 33.092  -21.716 1.00 34.11  ? 129 LYS D CA  1 
ATOM   11359 C  C   . LYS D 1 129 ? -29.966 31.902  -21.082 1.00 31.80  ? 129 LYS D C   1 
ATOM   11360 O  O   . LYS D 1 129 ? -29.819 31.641  -19.887 1.00 34.48  ? 129 LYS D O   1 
ATOM   11361 C  CB  . LYS D 1 129 ? -27.888 32.675  -22.263 1.00 38.20  ? 129 LYS D CB  1 
ATOM   11362 C  CG  . LYS D 1 129 ? -27.924 31.529  -23.277 1.00 34.32  ? 129 LYS D CG  1 
ATOM   11363 C  CD  . LYS D 1 129 ? -26.523 31.119  -23.656 1.00 36.42  ? 129 LYS D CD  1 
ATOM   11364 C  CE  . LYS D 1 129 ? -26.519 30.072  -24.743 1.00 36.99  ? 129 LYS D CE  1 
ATOM   11365 N  NZ  . LYS D 1 129 ? -25.148 29.496  -24.856 1.00 39.00  ? 129 LYS D NZ  1 
ATOM   11366 N  N   . HIS D 1 130 ? -30.740 31.190  -21.893 1.00 33.52  ? 130 HIS D N   1 
ATOM   11367 C  CA  . HIS D 1 130 ? -31.301 29.896  -21.514 1.00 28.52  ? 130 HIS D CA  1 
ATOM   11368 C  C   . HIS D 1 130 ? -30.302 28.806  -21.887 1.00 36.96  ? 130 HIS D C   1 
ATOM   11369 O  O   . HIS D 1 130 ? -30.154 28.472  -23.067 1.00 35.03  ? 130 HIS D O   1 
ATOM   11370 C  CB  . HIS D 1 130 ? -32.636 29.663  -22.220 1.00 40.19  ? 130 HIS D CB  1 
ATOM   11371 C  CG  . HIS D 1 130 ? -33.722 30.594  -21.785 1.00 40.91  ? 130 HIS D CG  1 
ATOM   11372 N  ND1 . HIS D 1 130 ? -33.878 31.856  -22.321 1.00 39.52  ? 130 HIS D ND1 1 
ATOM   11373 C  CD2 . HIS D 1 130 ? -34.713 30.446  -20.875 1.00 37.88  ? 130 HIS D CD2 1 
ATOM   11374 C  CE1 . HIS D 1 130 ? -34.911 32.448  -21.752 1.00 38.88  ? 130 HIS D CE1 1 
ATOM   11375 N  NE2 . HIS D 1 130 ? -35.437 31.613  -20.873 1.00 42.97  ? 130 HIS D NE2 1 
ATOM   11376 N  N   . VAL D 1 131 ? -29.625 28.244  -20.881 1.00 36.48  ? 131 VAL D N   1 
ATOM   11377 C  CA  . VAL D 1 131 ? -28.648 27.175  -21.063 1.00 30.84  ? 131 VAL D CA  1 
ATOM   11378 C  C   . VAL D 1 131 ? -29.184 25.903  -20.429 1.00 36.82  ? 131 VAL D C   1 
ATOM   11379 O  O   . VAL D 1 131 ? -29.898 25.935  -19.416 1.00 33.36  ? 131 VAL D O   1 
ATOM   11380 C  CB  . VAL D 1 131 ? -27.259 27.521  -20.472 1.00 35.84  ? 131 VAL D CB  1 
ATOM   11381 C  CG1 . VAL D 1 131 ? -26.486 28.371  -21.411 1.00 32.14  ? 131 VAL D CG1 1 
ATOM   11382 C  CG2 . VAL D 1 131 ? -27.390 28.263  -19.119 1.00 35.45  ? 131 VAL D CG2 1 
ATOM   11383 N  N   . THR D 1 132 ? -28.809 24.769  -21.025 1.00 34.66  ? 132 THR D N   1 
ATOM   11384 C  CA  . THR D 1 132 ? -29.210 23.444  -20.572 1.00 30.93  ? 132 THR D CA  1 
ATOM   11385 C  C   . THR D 1 132 ? -28.128 22.872  -19.665 1.00 33.56  ? 132 THR D C   1 
ATOM   11386 O  O   . THR D 1 132 ? -26.940 22.949  -19.979 1.00 33.30  ? 132 THR D O   1 
ATOM   11387 C  CB  . THR D 1 132 ? -29.437 22.524  -21.774 1.00 31.70  ? 132 THR D CB  1 
ATOM   11388 O  OG1 . THR D 1 132 ? -30.284 23.181  -22.722 1.00 35.04  ? 132 THR D OG1 1 
ATOM   11389 C  CG2 . THR D 1 132 ? -30.076 21.210  -21.366 1.00 34.36  ? 132 THR D CG2 1 
ATOM   11390 N  N   . LEU D 1 133 ? -28.534 22.302  -18.545 1.00 29.93  ? 133 LEU D N   1 
ATOM   11391 C  CA  . LEU D 1 133 ? -27.574 21.762  -17.609 1.00 27.12  ? 133 LEU D CA  1 
ATOM   11392 C  C   . LEU D 1 133 ? -27.151 20.388  -18.095 1.00 28.18  ? 133 LEU D C   1 
ATOM   11393 O  O   . LEU D 1 133 ? -27.966 19.643  -18.636 1.00 30.65  ? 133 LEU D O   1 
ATOM   11394 C  CB  . LEU D 1 133 ? -28.195 21.706  -16.208 1.00 30.66  ? 133 LEU D CB  1 
ATOM   11395 C  CG  . LEU D 1 133 ? -27.310 21.410  -14.996 1.00 24.67  ? 133 LEU D CG  1 
ATOM   11396 C  CD1 . LEU D 1 133 ? -26.730 22.706  -14.482 1.00 33.10  ? 133 LEU D CD1 1 
ATOM   11397 C  CD2 . LEU D 1 133 ? -28.097 20.712  -13.914 1.00 32.81  ? 133 LEU D CD2 1 
ATOM   11398 N  N   . ALA D 1 134 ? -25.870 20.065  -17.950 1.00 24.29  ? 134 ALA D N   1 
ATOM   11399 C  CA  . ALA D 1 134 ? -25.453 18.710  -18.257 1.00 28.92  ? 134 ALA D CA  1 
ATOM   11400 C  C   . ALA D 1 134 ? -26.356 17.740  -17.492 1.00 36.33  ? 134 ALA D C   1 
ATOM   11401 O  O   . ALA D 1 134 ? -26.601 17.947  -16.293 1.00 38.10  ? 134 ALA D O   1 
ATOM   11402 C  CB  . ALA D 1 134 ? -23.991 18.479  -17.888 1.00 26.36  ? 134 ALA D CB  1 
ATOM   11403 N  N   . PRO D 1 135 ? -26.891 16.710  -18.146 1.00 38.07  ? 135 PRO D N   1 
ATOM   11404 C  CA  . PRO D 1 135 ? -27.960 15.907  -17.533 1.00 38.78  ? 135 PRO D CA  1 
ATOM   11405 C  C   . PRO D 1 135 ? -27.497 15.155  -16.290 1.00 36.93  ? 135 PRO D C   1 
ATOM   11406 O  O   . PRO D 1 135 ? -26.487 14.445  -16.308 1.00 37.18  ? 135 PRO D O   1 
ATOM   11407 C  CB  . PRO D 1 135 ? -28.361 14.941  -18.658 1.00 39.40  ? 135 PRO D CB  1 
ATOM   11408 C  CG  . PRO D 1 135 ? -27.230 14.961  -19.627 1.00 38.79  ? 135 PRO D CG  1 
ATOM   11409 C  CD  . PRO D 1 135 ? -26.676 16.345  -19.556 1.00 41.83  ? 135 PRO D CD  1 
ATOM   11410 N  N   . GLU D 1 136 ? -28.262 15.304  -15.210 1.00 39.96  ? 136 GLU D N   1 
ATOM   11411 C  CA  . GLU D 1 136 ? -28.067 14.472  -14.029 1.00 38.49  ? 136 GLU D CA  1 
ATOM   11412 C  C   . GLU D 1 136 ? -28.810 13.155  -14.120 1.00 34.36  ? 136 GLU D C   1 
ATOM   11413 O  O   . GLU D 1 136 ? -28.394 12.187  -13.481 1.00 38.10  ? 136 GLU D O   1 
ATOM   11414 C  CB  . GLU D 1 136 ? -28.499 15.220  -12.768 1.00 35.03  ? 136 GLU D CB  1 
ATOM   11415 C  CG  . GLU D 1 136 ? -27.657 16.457  -12.493 1.00 35.43  ? 136 GLU D CG  1 
ATOM   11416 C  CD  . GLU D 1 136 ? -26.342 16.140  -11.813 1.00 36.73  ? 136 GLU D CD  1 
ATOM   11417 O  OE1 . GLU D 1 136 ? -26.183 15.019  -11.288 1.00 43.48  ? 136 GLU D OE1 1 
ATOM   11418 O  OE2 . GLU D 1 136 ? -25.460 17.015  -11.803 1.00 39.66  ? 136 GLU D OE2 1 
ATOM   11419 N  N   . ALA D 1 137 ? -29.884 13.094  -14.909 1.00 43.39  ? 137 ALA D N   1 
ATOM   11420 C  CA  . ALA D 1 137 ? -30.644 11.863  -15.103 1.00 38.77  ? 137 ALA D CA  1 
ATOM   11421 C  C   . ALA D 1 137 ? -29.772 10.753  -15.695 1.00 40.70  ? 137 ALA D C   1 
ATOM   11422 O  O   . ALA D 1 137 ? -28.745 11.003  -16.327 1.00 37.76  ? 137 ALA D O   1 
ATOM   11423 C  CB  . ALA D 1 137 ? -31.838 12.116  -16.019 1.00 42.59  ? 137 ALA D CB  1 
ATOM   11424 N  N   . SER D 1 138 ? -30.205 9.504   -15.484 1.00 40.49  ? 138 SER D N   1 
ATOM   11425 C  CA  . SER D 1 138 ? -29.449 8.346   -15.967 1.00 38.76  ? 138 SER D CA  1 
ATOM   11426 C  C   . SER D 1 138 ? -29.668 8.081   -17.455 1.00 39.56  ? 138 SER D C   1 
ATOM   11427 O  O   . SER D 1 138 ? -28.734 8.170   -18.258 1.00 42.13  ? 138 SER D O   1 
ATOM   11428 C  CB  . SER D 1 138 ? -29.817 7.104   -15.158 1.00 37.24  ? 138 SER D CB  1 
ATOM   11429 O  OG  . SER D 1 138 ? -29.560 5.944   -15.933 1.00 40.05  ? 138 SER D OG  1 
ATOM   11430 N  N   . GLY D 1 139 ? -30.897 7.725   -17.834 1.00 43.64  ? 139 GLY D N   1 
ATOM   11431 C  CA  . GLY D 1 139 ? -31.221 7.346   -19.198 1.00 36.37  ? 139 GLY D CA  1 
ATOM   11432 C  C   . GLY D 1 139 ? -31.148 5.860   -19.468 1.00 35.94  ? 139 GLY D C   1 
ATOM   11433 O  O   . GLY D 1 139 ? -31.376 5.434   -20.614 1.00 26.37  ? 139 GLY D O   1 
ATOM   11434 N  N   . ALA D 1 140 ? -30.823 5.064   -18.458 1.00 38.34  ? 140 ALA D N   1 
ATOM   11435 C  CA  . ALA D 1 140 ? -30.845 3.622   -18.611 1.00 39.44  ? 140 ALA D CA  1 
ATOM   11436 C  C   . ALA D 1 140 ? -32.202 3.202   -19.166 1.00 38.48  ? 140 ALA D C   1 
ATOM   11437 O  O   . ALA D 1 140 ? -33.219 3.839   -18.858 1.00 34.95  ? 140 ALA D O   1 
ATOM   11438 C  CB  . ALA D 1 140 ? -30.568 2.944   -17.264 1.00 37.79  ? 140 ALA D CB  1 
ATOM   11439 N  N   . PRO D 1 141 ? -32.261 2.165   -20.002 1.00 33.79  ? 141 PRO D N   1 
ATOM   11440 C  CA  . PRO D 1 141 ? -31.176 1.263   -20.419 1.00 38.80  ? 141 PRO D CA  1 
ATOM   11441 C  C   . PRO D 1 141 ? -30.380 1.691   -21.650 1.00 41.29  ? 141 PRO D C   1 
ATOM   11442 O  O   . PRO D 1 141 ? -29.466 0.962   -22.055 1.00 38.21  ? 141 PRO D O   1 
ATOM   11443 C  CB  . PRO D 1 141 ? -31.929 -0.023  -20.745 1.00 43.33  ? 141 PRO D CB  1 
ATOM   11444 C  CG  . PRO D 1 141 ? -33.209 0.482   -21.306 1.00 39.27  ? 141 PRO D CG  1 
ATOM   11445 C  CD  . PRO D 1 141 ? -33.564 1.717   -20.512 1.00 34.47  ? 141 PRO D CD  1 
ATOM   11446 N  N   . PHE D 1 142 ? -30.725 2.838   -22.234 1.00 42.17  ? 142 PHE D N   1 
ATOM   11447 C  CA  . PHE D 1 142 ? -30.168 3.235   -23.520 1.00 40.75  ? 142 PHE D CA  1 
ATOM   11448 C  C   . PHE D 1 142 ? -28.732 3.726   -23.358 1.00 39.27  ? 142 PHE D C   1 
ATOM   11449 O  O   . PHE D 1 142 ? -28.216 3.878   -22.247 1.00 37.64  ? 142 PHE D O   1 
ATOM   11450 C  CB  . PHE D 1 142 ? -31.042 4.313   -24.171 1.00 38.31  ? 142 PHE D CB  1 
ATOM   11451 C  CG  . PHE D 1 142 ? -32.514 3.960   -24.215 1.00 41.59  ? 142 PHE D CG  1 
ATOM   11452 C  CD1 . PHE D 1 142 ? -32.942 2.759   -24.766 1.00 37.06  ? 142 PHE D CD1 1 
ATOM   11453 C  CD2 . PHE D 1 142 ? -33.464 4.820   -23.689 1.00 37.74  ? 142 PHE D CD2 1 
ATOM   11454 C  CE1 . PHE D 1 142 ? -34.274 2.441   -24.803 1.00 39.59  ? 142 PHE D CE1 1 
ATOM   11455 C  CE2 . PHE D 1 142 ? -34.800 4.496   -23.727 1.00 38.78  ? 142 PHE D CE2 1 
ATOM   11456 C  CZ  . PHE D 1 142 ? -35.205 3.309   -24.286 1.00 35.41  ? 142 PHE D CZ  1 
ATOM   11457 N  N   . ARG D 1 143 ? -28.076 3.954   -24.493 1.00 38.94  ? 143 ARG D N   1 
ATOM   11458 C  CA  . ARG D 1 143 ? -26.768 4.602   -24.537 1.00 36.83  ? 143 ARG D CA  1 
ATOM   11459 C  C   . ARG D 1 143 ? -26.882 5.873   -25.364 1.00 38.53  ? 143 ARG D C   1 
ATOM   11460 O  O   . ARG D 1 143 ? -27.756 5.995   -26.229 1.00 42.01  ? 143 ARG D O   1 
ATOM   11461 C  CB  . ARG D 1 143 ? -25.691 3.677   -25.118 1.00 36.82  ? 143 ARG D CB  1 
ATOM   11462 C  CG  . ARG D 1 143 ? -25.574 2.351   -24.392 1.00 38.48  ? 143 ARG D CG  1 
ATOM   11463 C  CD  . ARG D 1 143 ? -24.476 1.476   -24.963 1.00 42.68  ? 143 ARG D CD  1 
ATOM   11464 N  NE  . ARG D 1 143 ? -23.161 1.929   -24.528 1.00 42.94  ? 143 ARG D NE  1 
ATOM   11465 C  CZ  . ARG D 1 143 ? -22.017 1.479   -25.022 1.00 40.46  ? 143 ARG D CZ  1 
ATOM   11466 N  NH1 . ARG D 1 143 ? -21.989 0.538   -25.958 1.00 40.44  ? 143 ARG D NH1 1 
ATOM   11467 N  NH2 . ARG D 1 143 ? -20.874 1.979   -24.561 1.00 37.96  ? 143 ARG D NH2 1 
ATOM   11468 N  N   . TYR D 1 144 ? -26.011 6.832   -25.089 1.00 34.12  ? 144 TYR D N   1 
ATOM   11469 C  CA  . TYR D 1 144 ? -26.209 8.186   -25.568 1.00 35.20  ? 144 TYR D CA  1 
ATOM   11470 C  C   . TYR D 1 144 ? -25.027 8.631   -26.414 1.00 36.93  ? 144 TYR D C   1 
ATOM   11471 O  O   . TYR D 1 144 ? -23.869 8.463   -26.020 1.00 34.95  ? 144 TYR D O   1 
ATOM   11472 C  CB  . TYR D 1 144 ? -26.471 9.119   -24.388 1.00 33.20  ? 144 TYR D CB  1 
ATOM   11473 C  CG  . TYR D 1 144 ? -27.808 8.757   -23.801 1.00 39.38  ? 144 TYR D CG  1 
ATOM   11474 C  CD1 . TYR D 1 144 ? -28.979 9.230   -24.377 1.00 41.10  ? 144 TYR D CD1 1 
ATOM   11475 C  CD2 . TYR D 1 144 ? -27.913 7.872   -22.731 1.00 39.37  ? 144 TYR D CD2 1 
ATOM   11476 C  CE1 . TYR D 1 144 ? -30.217 8.867   -23.880 1.00 41.13  ? 144 TYR D CE1 1 
ATOM   11477 C  CE2 . TYR D 1 144 ? -29.165 7.503   -22.225 1.00 37.56  ? 144 TYR D CE2 1 
ATOM   11478 C  CZ  . TYR D 1 144 ? -30.307 8.015   -22.808 1.00 36.98  ? 144 TYR D CZ  1 
ATOM   11479 O  OH  . TYR D 1 144 ? -31.555 7.677   -22.342 1.00 40.50  ? 144 TYR D OH  1 
ATOM   11480 N  N   . GLY D 1 145 ? -25.331 9.167   -27.597 1.00 35.66  ? 145 GLY D N   1 
ATOM   11481 C  CA  . GLY D 1 145 ? -24.319 9.711   -28.475 1.00 31.89  ? 145 GLY D CA  1 
ATOM   11482 C  C   . GLY D 1 145 ? -24.828 10.954  -29.170 1.00 34.64  ? 145 GLY D C   1 
ATOM   11483 O  O   . GLY D 1 145 ? -25.995 11.339  -29.032 1.00 34.50  ? 145 GLY D O   1 
ATOM   11484 N  N   . VAL D 1 146 ? -23.919 11.574  -29.918 1.00 29.76  ? 146 VAL D N   1 
ATOM   11485 C  CA  . VAL D 1 146 ? -24.212 12.678  -30.813 1.00 26.17  ? 146 VAL D CA  1 
ATOM   11486 C  C   . VAL D 1 146 ? -23.589 12.360  -32.167 1.00 34.47  ? 146 VAL D C   1 
ATOM   11487 O  O   . VAL D 1 146 ? -22.441 11.907  -32.248 1.00 30.99  ? 146 VAL D O   1 
ATOM   11488 C  CB  . VAL D 1 146 ? -23.645 14.018  -30.286 1.00 30.54  ? 146 VAL D CB  1 
ATOM   11489 C  CG1 . VAL D 1 146 ? -23.797 15.141  -31.334 1.00 26.03  ? 146 VAL D CG1 1 
ATOM   11490 C  CG2 . VAL D 1 146 ? -24.281 14.413  -28.990 1.00 27.92  ? 146 VAL D CG2 1 
ATOM   11491 N  N   . SER D 1 147 ? -24.331 12.601  -33.234 1.00 33.54  ? 147 SER D N   1 
ATOM   11492 C  CA  . SER D 1 147 ? -23.707 12.607  -34.537 1.00 32.73  ? 147 SER D CA  1 
ATOM   11493 C  C   . SER D 1 147 ? -23.211 14.003  -34.855 1.00 27.63  ? 147 SER D C   1 
ATOM   11494 O  O   . SER D 1 147 ? -23.867 14.997  -34.552 1.00 24.35  ? 147 SER D O   1 
ATOM   11495 C  CB  . SER D 1 147 ? -24.662 12.158  -35.626 1.00 32.87  ? 147 SER D CB  1 
ATOM   11496 O  OG  . SER D 1 147 ? -24.012 12.400  -36.838 1.00 29.78  ? 147 SER D OG  1 
ATOM   11497 N  N   . LEU D 1 148 ? -22.060 14.074  -35.510 1.00 34.16  ? 148 LEU D N   1 
ATOM   11498 C  CA  . LEU D 1 148 ? -21.600 15.380  -35.955 1.00 27.06  ? 148 LEU D CA  1 
ATOM   11499 C  C   . LEU D 1 148 ? -22.554 16.001  -36.979 1.00 25.40  ? 148 LEU D C   1 
ATOM   11500 O  O   . LEU D 1 148 ? -22.559 17.218  -37.135 1.00 24.57  ? 148 LEU D O   1 
ATOM   11501 C  CB  . LEU D 1 148 ? -20.182 15.255  -36.497 1.00 22.87  ? 148 LEU D CB  1 
ATOM   11502 C  CG  . LEU D 1 148 ? -19.109 14.913  -35.464 1.00 20.77  ? 148 LEU D CG  1 
ATOM   11503 C  CD1 . LEU D 1 148 ? -17.720 14.932  -36.092 1.00 23.37  ? 148 LEU D CD1 1 
ATOM   11504 C  CD2 . LEU D 1 148 ? -19.161 15.830  -34.281 1.00 20.65  ? 148 LEU D CD2 1 
ATOM   11505 N  N   . TYR D 1 149 ? -23.385 15.201  -37.656 1.00 29.34  ? 149 TYR D N   1 
ATOM   11506 C  CA  . TYR D 1 149 ? -24.499 15.757  -38.434 1.00 31.22  ? 149 TYR D CA  1 
ATOM   11507 C  C   . TYR D 1 149 ? -25.272 16.837  -37.665 1.00 34.32  ? 149 TYR D C   1 
ATOM   11508 O  O   . TYR D 1 149 ? -25.781 17.790  -38.264 1.00 31.70  ? 149 TYR D O   1 
ATOM   11509 C  CB  . TYR D 1 149 ? -25.446 14.634  -38.838 1.00 33.24  ? 149 TYR D CB  1 
ATOM   11510 C  CG  . TYR D 1 149 ? -26.576 15.054  -39.727 1.00 41.63  ? 149 TYR D CG  1 
ATOM   11511 C  CD1 . TYR D 1 149 ? -27.897 14.952  -39.301 1.00 43.86  ? 149 TYR D CD1 1 
ATOM   11512 C  CD2 . TYR D 1 149 ? -26.334 15.522  -41.016 1.00 53.68  ? 149 TYR D CD2 1 
ATOM   11513 C  CE1 . TYR D 1 149 ? -28.947 15.325  -40.121 1.00 41.37  ? 149 TYR D CE1 1 
ATOM   11514 C  CE2 . TYR D 1 149 ? -27.377 15.896  -41.851 1.00 45.59  ? 149 TYR D CE2 1 
ATOM   11515 C  CZ  . TYR D 1 149 ? -28.683 15.796  -41.398 1.00 51.66  ? 149 TYR D CZ  1 
ATOM   11516 O  OH  . TYR D 1 149 ? -29.716 16.173  -42.227 1.00 52.71  ? 149 TYR D OH  1 
ATOM   11517 N  N   . SER D 1 150 ? -25.381 16.703  -36.345 1.00 28.52  ? 150 SER D N   1 
ATOM   11518 C  CA  . SER D 1 150 ? -26.124 17.689  -35.575 1.00 29.19  ? 150 SER D CA  1 
ATOM   11519 C  C   . SER D 1 150 ? -25.524 19.072  -35.722 1.00 27.74  ? 150 SER D C   1 
ATOM   11520 O  O   . SER D 1 150 ? -26.241 20.065  -35.625 1.00 26.43  ? 150 SER D O   1 
ATOM   11521 C  CB  . SER D 1 150 ? -26.154 17.292  -34.101 1.00 26.29  ? 150 SER D CB  1 
ATOM   11522 O  OG  . SER D 1 150 ? -26.770 16.022  -33.944 1.00 32.56  ? 150 SER D OG  1 
ATOM   11523 N  N   . TYR D 1 151 ? -24.228 19.116  -36.002 1.00 27.41  ? 151 TYR D N   1 
ATOM   11524 C  CA  . TYR D 1 151 ? -23.504 20.403  -36.074 1.00 30.02  ? 151 TYR D CA  1 
ATOM   11525 C  C   . TYR D 1 151 ? -23.273 20.838  -37.523 1.00 31.91  ? 151 TYR D C   1 
ATOM   11526 O  O   . TYR D 1 151 ? -22.364 21.640  -37.750 1.00 35.23  ? 151 TYR D O   1 
ATOM   11527 C  CB  . TYR D 1 151 ? -22.198 20.272  -35.299 1.00 27.70  ? 151 TYR D CB  1 
ATOM   11528 C  CG  . TYR D 1 151 ? -22.402 19.947  -33.840 1.00 34.13  ? 151 TYR D CG  1 
ATOM   11529 C  CD1 . TYR D 1 151 ? -23.469 20.479  -33.135 1.00 31.28  ? 151 TYR D CD1 1 
ATOM   11530 C  CD2 . TYR D 1 151 ? -21.543 19.098  -33.164 1.00 26.91  ? 151 TYR D CD2 1 
ATOM   11531 C  CE1 . TYR D 1 151 ? -23.673 20.189  -31.797 1.00 33.05  ? 151 TYR D CE1 1 
ATOM   11532 C  CE2 . TYR D 1 151 ? -21.732 18.797  -31.826 1.00 34.41  ? 151 TYR D CE2 1 
ATOM   11533 C  CZ  . TYR D 1 151 ? -22.799 19.345  -31.139 1.00 32.39  ? 151 TYR D CZ  1 
ATOM   11534 O  OH  . TYR D 1 151 ? -22.990 19.045  -29.818 1.00 32.61  ? 151 TYR D OH  1 
ATOM   11535 N  N   . MET D 1 152 ? -24.079 20.337  -38.450 1.00 28.74  ? 152 MET D N   1 
ATOM   11536 C  CA  . MET D 1 152 ? -23.987 20.773  -39.866 1.00 30.49  ? 152 MET D CA  1 
ATOM   11537 C  C   . MET D 1 152 ? -24.081 22.299  -39.970 1.00 29.73  ? 152 MET D C   1 
ATOM   11538 O  O   . MET D 1 152 ? -24.895 22.876  -39.246 1.00 29.23  ? 152 MET D O   1 
ATOM   11539 C  CB  . MET D 1 152 ? -25.088 20.143  -40.717 1.00 33.22  ? 152 MET D CB  1 
ATOM   11540 C  CG  . MET D 1 152 ? -24.942 20.416  -42.197 1.00 41.18  ? 152 MET D CG  1 
ATOM   11541 S  SD  . MET D 1 152 ? -26.529 20.543  -43.044 1.00 44.93  ? 152 MET D SD  1 
ATOM   11542 C  CE  . MET D 1 152 ? -27.326 19.046  -42.483 1.00 37.29  ? 152 MET D CE  1 
ATOM   11543 N  N   . SER D 1 153 ? -23.265 22.900  -40.838 1.00 29.71  ? 153 SER D N   1 
ATOM   11544 C  CA  . SER D 1 153 ? -23.216 24.371  -41.052 1.00 28.43  ? 153 SER D CA  1 
ATOM   11545 C  C   . SER D 1 153 ? -22.326 25.027  -39.978 1.00 33.46  ? 153 SER D C   1 
ATOM   11546 O  O   . SER D 1 153 ? -21.473 25.827  -40.351 1.00 31.08  ? 153 SER D O   1 
ATOM   11547 C  CB  . SER D 1 153 ? -24.593 24.983  -41.201 1.00 32.57  ? 153 SER D CB  1 
ATOM   11548 O  OG  . SER D 1 153 ? -25.264 24.464  -42.334 1.00 35.53  ? 153 SER D OG  1 
ATOM   11549 N  N   . ASP D 1 154 ? -22.488 24.667  -38.703 1.00 31.62  ? 154 ASP D N   1 
ATOM   11550 C  CA  . ASP D 1 154 ? -21.570 25.171  -37.650 1.00 31.61  ? 154 ASP D CA  1 
ATOM   11551 C  C   . ASP D 1 154 ? -20.220 24.482  -37.848 1.00 30.90  ? 154 ASP D C   1 
ATOM   11552 O  O   . ASP D 1 154 ? -19.197 25.169  -37.775 1.00 31.93  ? 154 ASP D O   1 
ATOM   11553 C  CB  . ASP D 1 154 ? -22.130 24.965  -36.242 1.00 33.33  ? 154 ASP D CB  1 
ATOM   11554 C  CG  . ASP D 1 154 ? -23.332 25.826  -35.906 1.00 32.99  ? 154 ASP D CG  1 
ATOM   11555 O  OD1 . ASP D 1 154 ? -23.337 26.996  -36.297 1.00 30.06  ? 154 ASP D OD1 1 
ATOM   11556 O  OD2 . ASP D 1 154 ? -24.247 25.311  -35.246 1.00 37.22  ? 154 ASP D OD2 1 
ATOM   11557 N  N   . TYR D 1 155 ? -20.238 23.181  -38.117 1.00 29.17  ? 155 TYR D N   1 
ATOM   11558 C  CA  . TYR D 1 155 ? -18.999 22.463  -38.382 1.00 34.36  ? 155 TYR D CA  1 
ATOM   11559 C  C   . TYR D 1 155 ? -18.298 23.032  -39.597 1.00 29.20  ? 155 TYR D C   1 
ATOM   11560 O  O   . TYR D 1 155 ? -18.780 22.896  -40.722 1.00 30.69  ? 155 TYR D O   1 
ATOM   11561 C  CB  . TYR D 1 155 ? -19.227 20.964  -38.613 1.00 30.14  ? 155 TYR D CB  1 
ATOM   11562 C  CG  . TYR D 1 155 ? -17.972 20.148  -38.367 1.00 35.02  ? 155 TYR D CG  1 
ATOM   11563 C  CD1 . TYR D 1 155 ? -17.618 19.771  -37.069 1.00 34.30  ? 155 TYR D CD1 1 
ATOM   11564 C  CD2 . TYR D 1 155 ? -17.124 19.783  -39.411 1.00 32.15  ? 155 TYR D CD2 1 
ATOM   11565 C  CE1 . TYR D 1 155 ? -16.477 19.038  -36.813 1.00 29.05  ? 155 TYR D CE1 1 
ATOM   11566 C  CE2 . TYR D 1 155 ? -15.968 19.038  -39.165 1.00 30.73  ? 155 TYR D CE2 1 
ATOM   11567 C  CZ  . TYR D 1 155 ? -15.662 18.671  -37.857 1.00 28.82  ? 155 TYR D CZ  1 
ATOM   11568 O  OH  . TYR D 1 155 ? -14.535 17.942  -37.554 1.00 35.59  ? 155 TYR D OH  1 
ATOM   11569 N  N   . GLY D 1 156 ? -17.141 23.628  -39.381 1.00 29.24  ? 156 GLY D N   1 
ATOM   11570 C  CA  . GLY D 1 156 ? -16.374 24.200  -40.442 1.00 29.73  ? 156 GLY D CA  1 
ATOM   11571 C  C   . GLY D 1 156 ? -16.469 25.698  -40.524 1.00 26.53  ? 156 GLY D C   1 
ATOM   11572 O  O   . GLY D 1 156 ? -15.659 26.309  -41.225 1.00 30.37  ? 156 GLY D O   1 
ATOM   11573 N  N   . THR D 1 157 ? -17.436 26.304  -39.831 1.00 29.49  ? 157 THR D N   1 
ATOM   11574 C  CA  . THR D 1 157 ? -17.577 27.758  -39.791 1.00 25.77  ? 157 THR D CA  1 
ATOM   11575 C  C   . THR D 1 157 ? -17.414 28.312  -38.392 1.00 30.62  ? 157 THR D C   1 
ATOM   11576 O  O   . THR D 1 157 ? -16.757 29.350  -38.223 1.00 27.88  ? 157 THR D O   1 
ATOM   11577 C  CB  . THR D 1 157 ? -18.943 28.208  -40.356 1.00 25.42  ? 157 THR D CB  1 
ATOM   11578 O  OG1 . THR D 1 157 ? -20.007 27.758  -39.502 1.00 26.70  ? 157 THR D OG1 1 
ATOM   11579 C  CG2 . THR D 1 157 ? -19.174 27.644  -41.749 1.00 26.01  ? 157 THR D CG2 1 
ATOM   11580 N  N   . VAL D 1 158 ? -17.978 27.637  -37.383 1.00 26.72  ? 158 VAL D N   1 
ATOM   11581 C  CA  . VAL D 1 158 ? -17.845 28.043  -35.987 1.00 28.76  ? 158 VAL D CA  1 
ATOM   11582 C  C   . VAL D 1 158 ? -17.347 26.923  -35.081 1.00 32.97  ? 158 VAL D C   1 
ATOM   11583 O  O   . VAL D 1 158 ? -17.215 27.134  -33.873 1.00 26.71  ? 158 VAL D O   1 
ATOM   11584 C  CB  . VAL D 1 158 ? -19.175 28.600  -35.436 1.00 32.32  ? 158 VAL D CB  1 
ATOM   11585 C  CG1 . VAL D 1 158 ? -19.743 29.657  -36.358 1.00 29.79  ? 158 VAL D CG1 1 
ATOM   11586 C  CG2 . VAL D 1 158 ? -20.170 27.475  -35.258 1.00 29.72  ? 158 VAL D CG2 1 
ATOM   11587 N  N   . MET D 1 159 ? -17.066 25.735  -35.610 1.00 27.67  ? 159 MET D N   1 
ATOM   11588 C  CA  . MET D 1 159 ? -16.741 24.623  -34.740 1.00 30.64  ? 159 MET D CA  1 
ATOM   11589 C  C   . MET D 1 159 ? -15.854 23.632  -35.479 1.00 31.47  ? 159 MET D C   1 
ATOM   11590 O  O   . MET D 1 159 ? -16.039 23.379  -36.675 1.00 30.16  ? 159 MET D O   1 
ATOM   11591 C  CB  . MET D 1 159 ? -18.038 23.980  -34.217 1.00 33.59  ? 159 MET D CB  1 
ATOM   11592 C  CG  . MET D 1 159 ? -17.962 22.522  -33.919 1.00 35.24  ? 159 MET D CG  1 
ATOM   11593 S  SD  . MET D 1 159 ? -19.572 21.867  -33.438 1.00 37.03  ? 159 MET D SD  1 
ATOM   11594 C  CE  . MET D 1 159 ? -20.138 23.162  -32.353 1.00 30.28  ? 159 MET D CE  1 
ATOM   11595 N  N   . ASP D 1 160 ? -14.846 23.129  -34.775 1.00 32.66  ? 160 ASP D N   1 
ATOM   11596 C  CA  . ASP D 1 160 ? -13.967 22.111  -35.303 1.00 25.70  ? 160 ASP D CA  1 
ATOM   11597 C  C   . ASP D 1 160 ? -14.184 20.796  -34.544 1.00 31.08  ? 160 ASP D C   1 
ATOM   11598 O  O   . ASP D 1 160 ? -15.129 20.642  -33.755 1.00 26.43  ? 160 ASP D O   1 
ATOM   11599 C  CB  . ASP D 1 160 ? -12.525 22.591  -35.242 1.00 25.92  ? 160 ASP D CB  1 
ATOM   11600 C  CG  . ASP D 1 160 ? -12.115 23.039  -33.858 1.00 31.38  ? 160 ASP D CG  1 
ATOM   11601 O  OD1 . ASP D 1 160 ? -12.798 22.679  -32.872 1.00 28.34  ? 160 ASP D OD1 1 
ATOM   11602 O  OD2 . ASP D 1 160 ? -11.087 23.740  -33.753 1.00 28.29  ? 160 ASP D OD2 1 
ATOM   11603 N  N   . LEU D 1 161 ? -13.310 19.825  -34.806 1.00 30.10  ? 161 LEU D N   1 
ATOM   11604 C  CA  . LEU D 1 161 ? -13.524 18.484  -34.275 1.00 31.35  ? 161 LEU D CA  1 
ATOM   11605 C  C   . LEU D 1 161 ? -13.448 18.474  -32.756 1.00 27.23  ? 161 LEU D C   1 
ATOM   11606 O  O   . LEU D 1 161 ? -14.329 17.919  -32.090 1.00 29.81  ? 161 LEU D O   1 
ATOM   11607 C  CB  . LEU D 1 161 ? -12.509 17.508  -34.862 1.00 30.99  ? 161 LEU D CB  1 
ATOM   11608 C  CG  . LEU D 1 161 ? -12.599 16.103  -34.266 1.00 32.42  ? 161 LEU D CG  1 
ATOM   11609 C  CD1 . LEU D 1 161 ? -14.001 15.547  -34.437 1.00 31.36  ? 161 LEU D CD1 1 
ATOM   11610 C  CD2 . LEU D 1 161 ? -11.581 15.185  -34.891 1.00 27.56  ? 161 LEU D CD2 1 
ATOM   11611 N  N   . GLU D 1 162 ? -12.402 19.077  -32.189 1.00 21.29  ? 162 GLU D N   1 
ATOM   11612 C  CA  . GLU D 1 162 ? -12.258 19.046  -30.736 1.00 29.92  ? 162 GLU D CA  1 
ATOM   11613 C  C   . GLU D 1 162 ? -13.366 19.826  -30.043 1.00 33.22  ? 162 GLU D C   1 
ATOM   11614 O  O   . GLU D 1 162 ? -13.855 19.412  -28.985 1.00 25.72  ? 162 GLU D O   1 
ATOM   11615 C  CB  . GLU D 1 162 ? -10.904 19.597  -30.289 1.00 30.55  ? 162 GLU D CB  1 
ATOM   11616 C  CG  . GLU D 1 162 ? -10.697 19.344  -28.768 1.00 25.82  ? 162 GLU D CG  1 
ATOM   11617 C  CD  . GLU D 1 162 ? -9.343  19.784  -28.248 1.00 36.05  ? 162 GLU D CD  1 
ATOM   11618 O  OE1 . GLU D 1 162 ? -8.620  20.487  -29.003 1.00 34.66  ? 162 GLU D OE1 1 
ATOM   11619 O  OE2 . GLU D 1 162 ? -9.025  19.444  -27.071 1.00 29.69  ? 162 GLU D OE2 1 
ATOM   11620 N  N   . THR D 1 163 ? -13.748 20.980  -30.590 1.00 31.04  ? 163 THR D N   1 
ATOM   11621 C  CA  . THR D 1 163 ? -14.871 21.707  -30.004 1.00 30.86  ? 163 THR D CA  1 
ATOM   11622 C  C   . THR D 1 163 ? -16.137 20.854  -30.018 1.00 28.07  ? 163 THR D C   1 
ATOM   11623 O  O   . THR D 1 163 ? -16.912 20.850  -29.055 1.00 26.46  ? 163 THR D O   1 
ATOM   11624 C  CB  . THR D 1 163 ? -15.083 23.020  -30.752 1.00 26.38  ? 163 THR D CB  1 
ATOM   11625 O  OG1 . THR D 1 163 ? -13.860 23.762  -30.741 1.00 27.40  ? 163 THR D OG1 1 
ATOM   11626 C  CG2 . THR D 1 163 ? -16.195 23.838  -30.110 1.00 26.27  ? 163 THR D CG2 1 
ATOM   11627 N  N   . ALA D 1 164 ? -16.355 20.124  -31.107 1.00 28.24  ? 164 ALA D N   1 
ATOM   11628 C  CA  . ALA D 1 164 ? -17.464 19.184  -31.179 1.00 31.76  ? 164 ALA D CA  1 
ATOM   11629 C  C   . ALA D 1 164 ? -17.372 18.135  -30.070 1.00 33.33  ? 164 ALA D C   1 
ATOM   11630 O  O   . ALA D 1 164 ? -18.342 17.901  -29.337 1.00 34.79  ? 164 ALA D O   1 
ATOM   11631 C  CB  . ALA D 1 164 ? -17.471 18.518  -32.558 1.00 27.96  ? 164 ALA D CB  1 
ATOM   11632 N  N   . MET D 1 165 ? -16.210 17.492  -29.932 1.00 32.32  ? 165 MET D N   1 
ATOM   11633 C  CA  . MET D 1 165 ? -16.090 16.399  -28.973 1.00 28.38  ? 165 MET D CA  1 
ATOM   11634 C  C   . MET D 1 165 ? -16.212 16.909  -27.534 1.00 25.62  ? 165 MET D C   1 
ATOM   11635 O  O   . MET D 1 165 ? -16.873 16.275  -26.697 1.00 30.66  ? 165 MET D O   1 
ATOM   11636 C  CB  . MET D 1 165 ? -14.778 15.649  -29.225 1.00 29.04  ? 165 MET D CB  1 
ATOM   11637 C  CG  . MET D 1 165 ? -14.748 14.920  -30.607 1.00 24.52  ? 165 MET D CG  1 
ATOM   11638 S  SD  . MET D 1 165 ? -13.624 13.508  -30.826 1.00 39.66  ? 165 MET D SD  1 
ATOM   11639 C  CE  . MET D 1 165 ? -12.866 13.636  -29.286 1.00 26.51  ? 165 MET D CE  1 
ATOM   11640 N  N   . ALA D 1 166 ? -15.621 18.065  -27.226 1.00 26.94  ? 166 ALA D N   1 
ATOM   11641 C  CA  . ALA D 1 166 ? -15.831 18.661  -25.903 1.00 24.72  ? 166 ALA D CA  1 
ATOM   11642 C  C   . ALA D 1 166 ? -17.317 18.796  -25.581 1.00 30.48  ? 166 ALA D C   1 
ATOM   11643 O  O   . ALA D 1 166 ? -17.741 18.553  -24.446 1.00 21.67  ? 166 ALA D O   1 
ATOM   11644 C  CB  . ALA D 1 166 ? -15.154 20.025  -25.813 1.00 30.12  ? 166 ALA D CB  1 
ATOM   11645 N  N   . SER D 1 167 ? -18.123 19.202  -26.568 1.00 31.20  ? 167 SER D N   1 
ATOM   11646 C  CA  . SER D 1 167 ? -19.552 19.402  -26.344 1.00 27.59  ? 167 SER D CA  1 
ATOM   11647 C  C   . SER D 1 167 ? -20.284 18.087  -26.126 1.00 30.17  ? 167 SER D C   1 
ATOM   11648 O  O   . SER D 1 167 ? -21.258 18.041  -25.370 1.00 30.20  ? 167 SER D O   1 
ATOM   11649 C  CB  . SER D 1 167 ? -20.167 20.121  -27.541 1.00 29.58  ? 167 SER D CB  1 
ATOM   11650 O  OG  . SER D 1 167 ? -20.318 19.183  -28.602 1.00 22.90  ? 167 SER D OG  1 
ATOM   11651 N  N   . ILE D 1 168 ? -19.863 17.027  -26.814 1.00 25.96  ? 168 ILE D N   1 
ATOM   11652 C  CA  . ILE D 1 168 ? -20.514 15.735  -26.676 1.00 26.31  ? 168 ILE D CA  1 
ATOM   11653 C  C   . ILE D 1 168 ? -20.252 15.147  -25.295 1.00 30.43  ? 168 ILE D C   1 
ATOM   11654 O  O   . ILE D 1 168 ? -21.173 14.692  -24.610 1.00 31.93  ? 168 ILE D O   1 
ATOM   11655 C  CB  . ILE D 1 168 ? -20.027 14.777  -27.774 1.00 30.73  ? 168 ILE D CB  1 
ATOM   11656 C  CG1 . ILE D 1 168 ? -20.375 15.291  -29.174 1.00 29.78  ? 168 ILE D CG1 1 
ATOM   11657 C  CG2 . ILE D 1 168 ? -20.612 13.416  -27.546 1.00 24.81  ? 168 ILE D CG2 1 
ATOM   11658 C  CD1 . ILE D 1 168 ? -19.852 14.353  -30.296 1.00 29.79  ? 168 ILE D CD1 1 
ATOM   11659 N  N   . ALA D 1 169 ? -18.984 15.125  -24.879 1.00 28.91  ? 169 ALA D N   1 
ATOM   11660 C  CA  . ALA D 1 169 ? -18.624 14.552  -23.588 1.00 27.91  ? 169 ALA D CA  1 
ATOM   11661 C  C   . ALA D 1 169 ? -19.326 15.279  -22.441 1.00 34.94  ? 169 ALA D C   1 
ATOM   11662 O  O   . ALA D 1 169 ? -19.898 14.639  -21.547 1.00 32.08  ? 169 ALA D O   1 
ATOM   11663 C  CB  . ALA D 1 169 ? -17.109 14.598  -23.405 1.00 28.15  ? 169 ALA D CB  1 
ATOM   11664 N  N   . ASP D 1 170 ? -19.318 16.622  -22.472 1.00 28.35  ? 170 ASP D N   1 
ATOM   11665 C  CA  . ASP D 1 170 ? -19.947 17.428  -21.422 1.00 35.47  ? 170 ASP D CA  1 
ATOM   11666 C  C   . ASP D 1 170 ? -21.410 17.072  -21.213 1.00 35.68  ? 170 ASP D C   1 
ATOM   11667 O  O   . ASP D 1 170 ? -21.980 17.404  -20.164 1.00 35.61  ? 170 ASP D O   1 
ATOM   11668 C  CB  . ASP D 1 170 ? -19.846 18.913  -21.765 1.00 30.04  ? 170 ASP D CB  1 
ATOM   11669 C  CG  . ASP D 1 170 ? -20.124 19.831  -20.565 1.00 34.46  ? 170 ASP D CG  1 
ATOM   11670 O  OD1 . ASP D 1 170 ? -19.289 19.898  -19.649 1.00 29.10  ? 170 ASP D OD1 1 
ATOM   11671 O  OD2 . ASP D 1 170 ? -21.169 20.509  -20.553 1.00 32.81  ? 170 ASP D OD2 1 
ATOM   11672 N  N   . LEU D 1 171 ? -22.028 16.439  -22.202 1.00 33.31  ? 171 LEU D N   1 
ATOM   11673 C  CA  . LEU D 1 171 ? -23.416 16.004  -22.162 1.00 34.61  ? 171 LEU D CA  1 
ATOM   11674 C  C   . LEU D 1 171 ? -23.590 14.640  -21.512 1.00 34.58  ? 171 LEU D C   1 
ATOM   11675 O  O   . LEU D 1 171 ? -24.686 14.070  -21.568 1.00 38.37  ? 171 LEU D O   1 
ATOM   11676 C  CB  . LEU D 1 171 ? -23.964 15.960  -23.594 1.00 40.27  ? 171 LEU D CB  1 
ATOM   11677 C  CG  . LEU D 1 171 ? -24.686 17.210  -24.054 1.00 36.64  ? 171 LEU D CG  1 
ATOM   11678 C  CD1 . LEU D 1 171 ? -25.117 17.024  -25.493 1.00 32.65  ? 171 LEU D CD1 1 
ATOM   11679 C  CD2 . LEU D 1 171 ? -25.887 17.395  -23.135 1.00 35.66  ? 171 LEU D CD2 1 
ATOM   11680 N  N   . GLY D 1 172 ? -22.528 14.076  -20.945 1.00 37.87  ? 172 GLY D N   1 
ATOM   11681 C  CA  . GLY D 1 172 ? -22.581 12.695  -20.528 1.00 40.43  ? 172 GLY D CA  1 
ATOM   11682 C  C   . GLY D 1 172 ? -22.598 11.685  -21.653 1.00 37.40  ? 172 GLY D C   1 
ATOM   11683 O  O   . GLY D 1 172 ? -22.515 10.479  -21.384 1.00 41.52  ? 172 GLY D O   1 
ATOM   11684 N  N   . ALA D 1 173 ? -22.686 12.122  -22.906 1.00 32.16  ? 173 ALA D N   1 
ATOM   11685 C  CA  . ALA D 1 173 ? -22.694 11.157  -23.993 1.00 29.41  ? 173 ALA D CA  1 
ATOM   11686 C  C   . ALA D 1 173 ? -21.345 10.456  -24.083 1.00 26.90  ? 173 ALA D C   1 
ATOM   11687 O  O   . ALA D 1 173 ? -20.332 10.940  -23.596 1.00 32.37  ? 173 ALA D O   1 
ATOM   11688 C  CB  . ALA D 1 173 ? -23.030 11.837  -25.324 1.00 32.12  ? 173 ALA D CB  1 
ATOM   11689 N  N   . THR D 1 174 ? -21.349 9.300   -24.724 1.00 27.74  ? 174 THR D N   1 
ATOM   11690 C  CA  . THR D 1 174 ? -20.175 8.465   -24.848 1.00 29.31  ? 174 THR D CA  1 
ATOM   11691 C  C   . THR D 1 174 ? -19.921 8.039   -26.279 1.00 28.89  ? 174 THR D C   1 
ATOM   11692 O  O   . THR D 1 174 ? -18.846 7.500   -26.551 1.00 28.38  ? 174 THR D O   1 
ATOM   11693 C  CB  . THR D 1 174 ? -20.300 7.177   -23.999 1.00 32.63  ? 174 THR D CB  1 
ATOM   11694 O  OG1 . THR D 1 174 ? -21.368 6.361   -24.507 1.00 31.72  ? 174 THR D OG1 1 
ATOM   11695 C  CG2 . THR D 1 174 ? -20.552 7.483   -22.532 1.00 31.45  ? 174 THR D CG2 1 
ATOM   11696 N  N   . GLY D 1 175 ? -20.888 8.208   -27.182 1.00 30.98  ? 175 GLY D N   1 
ATOM   11697 C  CA  . GLY D 1 175 ? -20.751 7.790   -28.568 1.00 27.58  ? 175 GLY D CA  1 
ATOM   11698 C  C   . GLY D 1 175 ? -20.609 9.026   -29.444 1.00 30.45  ? 175 GLY D C   1 
ATOM   11699 O  O   . GLY D 1 175 ? -21.194 10.075  -29.157 1.00 29.47  ? 175 GLY D O   1 
ATOM   11700 N  N   . ILE D 1 176 ? -19.794 8.917   -30.488 1.00 30.32  ? 176 ILE D N   1 
ATOM   11701 C  CA  . ILE D 1 176 ? -19.712 9.959   -31.504 1.00 24.55  ? 176 ILE D CA  1 
ATOM   11702 C  C   . ILE D 1 176 ? -19.926 9.297   -32.856 1.00 28.99  ? 176 ILE D C   1 
ATOM   11703 O  O   . ILE D 1 176 ? -19.236 8.331   -33.201 1.00 27.44  ? 176 ILE D O   1 
ATOM   11704 C  CB  . ILE D 1 176 ? -18.386 10.733  -31.449 1.00 29.03  ? 176 ILE D CB  1 
ATOM   11705 C  CG1 . ILE D 1 176 ? -18.233 11.631  -32.685 1.00 29.68  ? 176 ILE D CG1 1 
ATOM   11706 C  CG2 . ILE D 1 176 ? -17.208 9.793   -31.291 1.00 27.87  ? 176 ILE D CG2 1 
ATOM   11707 C  CD1 . ILE D 1 176 ? -17.230 12.743  -32.468 1.00 27.98  ? 176 ILE D CD1 1 
ATOM   11708 N  N   . GLU D 1 177 ? -20.931 9.759   -33.584 1.00 27.28  ? 177 GLU D N   1 
ATOM   11709 C  CA  . GLU D 1 177 ? -21.188 9.261   -34.922 1.00 29.70  ? 177 GLU D CA  1 
ATOM   11710 C  C   . GLU D 1 177 ? -20.737 10.346  -35.894 1.00 26.16  ? 177 GLU D C   1 
ATOM   11711 O  O   . GLU D 1 177 ? -20.748 11.537  -35.558 1.00 27.94  ? 177 GLU D O   1 
ATOM   11712 C  CB  . GLU D 1 177 ? -22.679 8.889   -35.074 1.00 28.00  ? 177 GLU D CB  1 
ATOM   11713 C  CG  . GLU D 1 177 ? -23.231 8.809   -36.474 1.00 31.33  ? 177 GLU D CG  1 
ATOM   11714 C  CD  . GLU D 1 177 ? -24.706 8.435   -36.515 1.00 36.67  ? 177 GLU D CD  1 
ATOM   11715 O  OE1 . GLU D 1 177 ? -25.462 8.883   -35.615 1.00 35.71  ? 177 GLU D OE1 1 
ATOM   11716 O  OE2 . GLU D 1 177 ? -25.108 7.708   -37.457 1.00 34.11  ? 177 GLU D OE2 1 
ATOM   11717 N  N   . ILE D 1 178 ? -20.269 9.940   -37.072 1.00 26.95  ? 178 ILE D N   1 
ATOM   11718 C  CA  . ILE D 1 178 ? -19.804 10.899  -38.072 1.00 27.26  ? 178 ILE D CA  1 
ATOM   11719 C  C   . ILE D 1 178 ? -20.270 10.460  -39.462 1.00 27.81  ? 178 ILE D C   1 
ATOM   11720 O  O   . ILE D 1 178 ? -20.826 9.379   -39.654 1.00 30.14  ? 178 ILE D O   1 
ATOM   11721 C  CB  . ILE D 1 178 ? -18.266 11.087  -38.053 1.00 24.23  ? 178 ILE D CB  1 
ATOM   11722 C  CG1 . ILE D 1 178 ? -17.560 9.972   -38.832 1.00 26.64  ? 178 ILE D CG1 1 
ATOM   11723 C  CG2 . ILE D 1 178 ? -17.700 11.229  -36.632 1.00 24.14  ? 178 ILE D CG2 1 
ATOM   11724 C  CD1 . ILE D 1 178 ? -16.046 10.122  -38.803 1.00 25.18  ? 178 ILE D CD1 1 
ATOM   11725 N  N   . LEU D 1 179 ? -20.072 11.345  -40.433 1.00 33.95  ? 179 LEU D N   1 
ATOM   11726 C  CA  . LEU D 1 179 ? -20.214 11.019  -41.843 1.00 29.83  ? 179 LEU D CA  1 
ATOM   11727 C  C   . LEU D 1 179 ? -18.811 11.058  -42.425 1.00 28.92  ? 179 LEU D C   1 
ATOM   11728 O  O   . LEU D 1 179 ? -18.140 12.090  -42.332 1.00 29.11  ? 179 LEU D O   1 
ATOM   11729 C  CB  . LEU D 1 179 ? -21.118 12.024  -42.561 1.00 32.59  ? 179 LEU D CB  1 
ATOM   11730 C  CG  . LEU D 1 179 ? -22.503 12.399  -42.028 1.00 30.66  ? 179 LEU D CG  1 
ATOM   11731 C  CD1 . LEU D 1 179 ? -23.112 13.475  -42.915 1.00 29.84  ? 179 LEU D CD1 1 
ATOM   11732 C  CD2 . LEU D 1 179 ? -23.428 11.201  -41.962 1.00 29.35  ? 179 LEU D CD2 1 
ATOM   11733 N  N   . GLY D 1 180 ? -18.363 9.939   -42.997 1.00 27.46  ? 180 GLY D N   1 
ATOM   11734 C  CA  . GLY D 1 180 ? -16.984 9.856   -43.455 1.00 24.40  ? 180 GLY D CA  1 
ATOM   11735 C  C   . GLY D 1 180 ? -16.627 10.936  -44.465 1.00 25.70  ? 180 GLY D C   1 
ATOM   11736 O  O   . GLY D 1 180 ? -15.537 11.508  -44.408 1.00 25.41  ? 180 GLY D O   1 
ATOM   11737 N  N   . GLU D 1 181 ? -17.542 11.233  -45.390 1.00 26.89  ? 181 GLU D N   1 
ATOM   11738 C  CA  . GLU D 1 181 ? -17.348 12.259  -46.419 1.00 27.93  ? 181 GLU D CA  1 
ATOM   11739 C  C   . GLU D 1 181 ? -17.617 13.663  -45.915 1.00 27.67  ? 181 GLU D C   1 
ATOM   11740 O  O   . GLU D 1 181 ? -17.499 14.621  -46.692 1.00 31.26  ? 181 GLU D O   1 
ATOM   11741 C  CB  . GLU D 1 181 ? -18.239 11.970  -47.633 1.00 28.82  ? 181 GLU D CB  1 
ATOM   11742 C  CG  . GLU D 1 181 ? -17.685 10.855  -48.497 1.00 30.58  ? 181 GLU D CG  1 
ATOM   11743 C  CD  . GLU D 1 181 ? -18.495 10.630  -49.741 1.00 30.87  ? 181 GLU D CD  1 
ATOM   11744 O  OE1 . GLU D 1 181 ? -18.557 11.554  -50.596 1.00 31.92  ? 181 GLU D OE1 1 
ATOM   11745 O  OE2 . GLU D 1 181 ? -19.093 9.536   -49.841 1.00 30.36  ? 181 GLU D OE2 1 
ATOM   11746 N  N   . ALA D 1 182 ? -17.975 13.817  -44.644 1.00 24.14  ? 182 ALA D N   1 
ATOM   11747 C  CA  . ALA D 1 182 ? -18.032 15.130  -44.029 1.00 25.31  ? 182 ALA D CA  1 
ATOM   11748 C  C   . ALA D 1 182 ? -16.867 15.404  -43.096 1.00 25.65  ? 182 ALA D C   1 
ATOM   11749 O  O   . ALA D 1 182 ? -16.255 16.469  -43.177 1.00 27.80  ? 182 ALA D O   1 
ATOM   11750 C  CB  . ALA D 1 182 ? -19.339 15.311  -43.260 1.00 26.72  ? 182 ALA D CB  1 
ATOM   11751 N  N   . HIS D 1 183 ? -16.519 14.468  -42.218 1.00 25.98  ? 183 HIS D N   1 
ATOM   11752 C  CA  . HIS D 1 183 ? -15.684 14.813  -41.072 1.00 27.86  ? 183 HIS D CA  1 
ATOM   11753 C  C   . HIS D 1 183 ? -14.300 14.213  -41.106 1.00 23.35  ? 183 HIS D C   1 
ATOM   11754 O  O   . HIS D 1 183 ? -13.538 14.455  -40.171 1.00 26.69  ? 183 HIS D O   1 
ATOM   11755 C  CB  . HIS D 1 183 ? -16.379 14.409  -39.770 1.00 28.67  ? 183 HIS D CB  1 
ATOM   11756 C  CG  . HIS D 1 183 ? -17.801 14.849  -39.711 1.00 25.93  ? 183 HIS D CG  1 
ATOM   11757 N  ND1 . HIS D 1 183 ? -18.854 13.965  -39.708 1.00 29.01  ? 183 HIS D ND1 1 
ATOM   11758 C  CD2 . HIS D 1 183 ? -18.345 16.086  -39.686 1.00 24.27  ? 183 HIS D CD2 1 
ATOM   11759 C  CE1 . HIS D 1 183 ? -19.988 14.637  -39.672 1.00 26.15  ? 183 HIS D CE1 1 
ATOM   11760 N  NE2 . HIS D 1 183 ? -19.705 15.926  -39.669 1.00 28.62  ? 183 HIS D NE2 1 
ATOM   11761 N  N   . VAL D 1 184 ? -13.952 13.457  -42.144 1.00 20.10  ? 184 VAL D N   1 
ATOM   11762 C  CA  . VAL D 1 184 ? -12.610 12.901  -42.306 1.00 23.90  ? 184 VAL D CA  1 
ATOM   11763 C  C   . VAL D 1 184 ? -11.830 13.789  -43.270 1.00 24.50  ? 184 VAL D C   1 
ATOM   11764 O  O   . VAL D 1 184 ? -12.004 13.654  -44.486 1.00 24.29  ? 184 VAL D O   1 
ATOM   11765 C  CB  . VAL D 1 184 ? -12.648 11.452  -42.830 1.00 22.10  ? 184 VAL D CB  1 
ATOM   11766 C  CG1 . VAL D 1 184 ? -11.230 10.941  -43.046 1.00 22.69  ? 184 VAL D CG1 1 
ATOM   11767 C  CG2 . VAL D 1 184 ? -13.350 10.536  -41.834 1.00 27.02  ? 184 VAL D CG2 1 
ATOM   11768 N  N   . PRO D 1 185 ? -10.996 14.711  -42.799 1.00 23.97  ? 185 PRO D N   1 
ATOM   11769 C  CA  . PRO D 1 185 ? -10.260 15.582  -43.740 1.00 26.71  ? 185 PRO D CA  1 
ATOM   11770 C  C   . PRO D 1 185 ? -9.461  14.765  -44.741 1.00 24.59  ? 185 PRO D C   1 
ATOM   11771 O  O   . PRO D 1 185 ? -8.842  13.759  -44.390 1.00 30.44  ? 185 PRO D O   1 
ATOM   11772 C  CB  . PRO D 1 185 ? -9.342  16.405  -42.833 1.00 23.19  ? 185 PRO D CB  1 
ATOM   11773 C  CG  . PRO D 1 185 ? -10.047 16.406  -41.505 1.00 27.82  ? 185 PRO D CG  1 
ATOM   11774 C  CD  . PRO D 1 185 ? -10.697 15.035  -41.397 1.00 23.50  ? 185 PRO D CD  1 
ATOM   11775 N  N   . ASN D 1 186 ? -9.468  15.216  -45.998 1.00 26.72  ? 186 ASN D N   1 
ATOM   11776 C  CA  . ASN D 1 186 ? -8.772  14.549  -47.093 1.00 25.73  ? 186 ASN D CA  1 
ATOM   11777 C  C   . ASN D 1 186 ? -9.347  13.176  -47.385 1.00 27.92  ? 186 ASN D C   1 
ATOM   11778 O  O   . ASN D 1 186 ? -8.633  12.309  -47.893 1.00 29.95  ? 186 ASN D O   1 
ATOM   11779 C  CB  . ASN D 1 186 ? -7.261  14.426  -46.838 1.00 26.77  ? 186 ASN D CB  1 
ATOM   11780 C  CG  . ASN D 1 186 ? -6.476  14.279  -48.118 1.00 30.72  ? 186 ASN D CG  1 
ATOM   11781 O  OD1 . ASN D 1 186 ? -6.722  15.010  -49.074 1.00 29.27  ? 186 ASN D OD1 1 
ATOM   11782 N  ND2 . ASN D 1 186 ? -5.542  13.324  -48.159 1.00 25.53  ? 186 ASN D ND2 1 
ATOM   11783 N  N   . TYR D 1 187 ? -10.618 12.965  -47.039 1.00 22.02  ? 187 TYR D N   1 
ATOM   11784 C  CA  . TYR D 1 187 ? -11.298 11.740  -47.391 1.00 26.69  ? 187 TYR D CA  1 
ATOM   11785 C  C   . TYR D 1 187 ? -11.008 11.425  -48.851 1.00 26.23  ? 187 TYR D C   1 
ATOM   11786 O  O   . TYR D 1 187 ? -11.067 12.328  -49.695 1.00 26.02  ? 187 TYR D O   1 
ATOM   11787 C  CB  . TYR D 1 187 ? -12.803 11.880  -47.165 1.00 26.72  ? 187 TYR D CB  1 
ATOM   11788 C  CG  . TYR D 1 187 ? -13.590 10.684  -47.649 1.00 28.73  ? 187 TYR D CG  1 
ATOM   11789 C  CD1 . TYR D 1 187 ? -13.915 10.541  -48.993 1.00 27.01  ? 187 TYR D CD1 1 
ATOM   11790 C  CD2 . TYR D 1 187 ? -14.016 9.694   -46.751 1.00 26.04  ? 187 TYR D CD2 1 
ATOM   11791 C  CE1 . TYR D 1 187 ? -14.620 9.454   -49.441 1.00 28.66  ? 187 TYR D CE1 1 
ATOM   11792 C  CE2 . TYR D 1 187 ? -14.735 8.600   -47.189 1.00 28.63  ? 187 TYR D CE2 1 
ATOM   11793 C  CZ  . TYR D 1 187 ? -15.033 8.479   -48.539 1.00 29.48  ? 187 TYR D CZ  1 
ATOM   11794 O  OH  . TYR D 1 187 ? -15.740 7.386   -48.993 1.00 22.84  ? 187 TYR D OH  1 
ATOM   11795 N  N   . PRO D 1 188 ? -10.698 10.166  -49.187 1.00 23.86  ? 188 PRO D N   1 
ATOM   11796 C  CA  . PRO D 1 188 ? -10.755 9.070   -48.211 1.00 29.33  ? 188 PRO D CA  1 
ATOM   11797 C  C   . PRO D 1 188 ? -9.425  8.798   -47.516 1.00 27.24  ? 188 PRO D C   1 
ATOM   11798 O  O   . PRO D 1 188 ? -9.265  7.752   -46.912 1.00 28.73  ? 188 PRO D O   1 
ATOM   11799 C  CB  . PRO D 1 188 ? -11.151 7.866   -49.079 1.00 26.43  ? 188 PRO D CB  1 
ATOM   11800 C  CG  . PRO D 1 188 ? -10.437 8.127   -50.364 1.00 23.86  ? 188 PRO D CG  1 
ATOM   11801 C  CD  . PRO D 1 188 ? -10.449 9.661   -50.555 1.00 27.71  ? 188 PRO D CD  1 
ATOM   11802 N  N   . ASN D 1 189 ? -8.469  9.717   -47.608 1.00 29.57  ? 189 ASN D N   1 
ATOM   11803 C  CA  . ASN D 1 189 ? -7.095  9.460   -47.177 1.00 28.85  ? 189 ASN D CA  1 
ATOM   11804 C  C   . ASN D 1 189 ? -6.723  10.368  -46.009 1.00 26.14  ? 189 ASN D C   1 
ATOM   11805 O  O   . ASN D 1 189 ? -5.889  11.265  -46.152 1.00 26.10  ? 189 ASN D O   1 
ATOM   11806 C  CB  . ASN D 1 189 ? -6.121  9.652   -48.338 1.00 27.01  ? 189 ASN D CB  1 
ATOM   11807 C  CG  . ASN D 1 189 ? -6.410  8.728   -49.518 1.00 27.59  ? 189 ASN D CG  1 
ATOM   11808 O  OD1 . ASN D 1 189 ? -6.759  7.567   -49.347 1.00 27.97  ? 189 ASN D OD1 1 
ATOM   11809 N  ND2 . ASN D 1 189 ? -6.277  9.254   -50.721 1.00 25.25  ? 189 ASN D ND2 1 
ATOM   11810 N  N   . PRO D 1 190 ? -7.271  10.129  -44.823 1.00 27.31  ? 190 PRO D N   1 
ATOM   11811 C  CA  . PRO D 1 190 ? -6.829  10.914  -43.669 1.00 28.89  ? 190 PRO D CA  1 
ATOM   11812 C  C   . PRO D 1 190 ? -5.348  10.677  -43.443 1.00 30.19  ? 190 PRO D C   1 
ATOM   11813 O  O   . PRO D 1 190 ? -4.841  9.567   -43.627 1.00 31.53  ? 190 PRO D O   1 
ATOM   11814 C  CB  . PRO D 1 190 ? -7.670  10.357  -42.520 1.00 27.15  ? 190 PRO D CB  1 
ATOM   11815 C  CG  . PRO D 1 190 ? -7.861  8.950   -42.878 1.00 25.39  ? 190 PRO D CG  1 
ATOM   11816 C  CD  . PRO D 1 190 ? -8.055  8.964   -44.394 1.00 27.54  ? 190 PRO D CD  1 
ATOM   11817 N  N   . SER D 1 191 ? -4.645  11.739  -43.090 1.00 24.97  ? 191 SER D N   1 
ATOM   11818 C  CA  . SER D 1 191 ? -3.242  11.594  -42.788 1.00 26.65  ? 191 SER D CA  1 
ATOM   11819 C  C   . SER D 1 191 ? -3.073  10.812  -41.486 1.00 28.48  ? 191 SER D C   1 
ATOM   11820 O  O   . SER D 1 191 ? -3.985  10.721  -40.656 1.00 26.89  ? 191 SER D O   1 
ATOM   11821 C  CB  . SER D 1 191 ? -2.581  12.966  -42.671 1.00 26.58  ? 191 SER D CB  1 
ATOM   11822 O  OG  . SER D 1 191 ? -3.210  13.698  -41.644 1.00 27.63  ? 191 SER D OG  1 
ATOM   11823 N  N   . ASP D 1 192 ? -1.873  10.252  -41.305 1.00 25.41  ? 192 ASP D N   1 
ATOM   11824 C  CA  . ASP D 1 192 ? -1.565  9.586   -40.046 1.00 29.28  ? 192 ASP D CA  1 
ATOM   11825 C  C   . ASP D 1 192 ? -1.576  10.567  -38.884 1.00 27.17  ? 192 ASP D C   1 
ATOM   11826 O  O   . ASP D 1 192 ? -1.858  10.189  -37.749 1.00 29.58  ? 192 ASP D O   1 
ATOM   11827 C  CB  . ASP D 1 192 ? -0.203  8.913   -40.130 1.00 28.12  ? 192 ASP D CB  1 
ATOM   11828 C  CG  . ASP D 1 192 ? -0.188  7.752   -41.076 1.00 27.21  ? 192 ASP D CG  1 
ATOM   11829 O  OD1 . ASP D 1 192 ? -1.255  7.408   -41.626 1.00 29.49  ? 192 ASP D OD1 1 
ATOM   11830 O  OD2 . ASP D 1 192 ? 0.909   7.199   -41.272 1.00 32.62  ? 192 ASP D OD2 1 
ATOM   11831 N  N   . GLU D 1 193 ? -1.263  11.826  -39.140 1.00 28.61  ? 193 GLU D N   1 
ATOM   11832 C  CA  . GLU D 1 193 ? -1.292  12.789  -38.052 1.00 30.68  ? 193 GLU D CA  1 
ATOM   11833 C  C   . GLU D 1 193 ? -2.719  13.121  -37.641 1.00 31.05  ? 193 GLU D C   1 
ATOM   11834 O  O   . GLU D 1 193 ? -2.985  13.335  -36.455 1.00 32.49  ? 193 GLU D O   1 
ATOM   11835 C  CB  . GLU D 1 193 ? -0.508  14.034  -38.459 1.00 37.44  ? 193 GLU D CB  1 
ATOM   11836 C  CG  . GLU D 1 193 ? -1.059  15.339  -37.974 1.00 43.31  ? 193 GLU D CG  1 
ATOM   11837 C  CD  . GLU D 1 193 ? -0.520  16.487  -38.807 1.00 48.52  ? 193 GLU D CD  1 
ATOM   11838 O  OE1 . GLU D 1 193 ? 0.651   16.866  -38.575 1.00 54.30  ? 193 GLU D OE1 1 
ATOM   11839 O  OE2 . GLU D 1 193 ? -1.249  16.987  -39.705 1.00 44.56  ? 193 GLU D OE2 1 
ATOM   11840 N  N   . TRP D 1 194 ? -3.658  13.138  -38.582 1.00 26.23  ? 194 TRP D N   1 
ATOM   11841 C  CA  . TRP D 1 194 ? -5.040  13.348  -38.177 1.00 28.18  ? 194 TRP D CA  1 
ATOM   11842 C  C   . TRP D 1 194 ? -5.630  12.101  -37.521 1.00 28.67  ? 194 TRP D C   1 
ATOM   11843 O  O   . TRP D 1 194 ? -6.462  12.218  -36.613 1.00 27.19  ? 194 TRP D O   1 
ATOM   11844 C  CB  . TRP D 1 194 ? -5.905  13.750  -39.364 1.00 25.16  ? 194 TRP D CB  1 
ATOM   11845 C  CG  . TRP D 1 194 ? -7.307  14.047  -38.978 1.00 24.04  ? 194 TRP D CG  1 
ATOM   11846 C  CD1 . TRP D 1 194 ? -7.813  15.261  -38.618 1.00 25.00  ? 194 TRP D CD1 1 
ATOM   11847 C  CD2 . TRP D 1 194 ? -8.396  13.113  -38.895 1.00 25.26  ? 194 TRP D CD2 1 
ATOM   11848 N  NE1 . TRP D 1 194 ? -9.150  15.144  -38.307 1.00 27.73  ? 194 TRP D NE1 1 
ATOM   11849 C  CE2 . TRP D 1 194 ? -9.531  13.833  -38.485 1.00 27.78  ? 194 TRP D CE2 1 
ATOM   11850 C  CE3 . TRP D 1 194 ? -8.515  11.741  -39.130 1.00 27.54  ? 194 TRP D CE3 1 
ATOM   11851 C  CZ2 . TRP D 1 194 ? -10.778 13.229  -38.314 1.00 24.00  ? 194 TRP D CZ2 1 
ATOM   11852 C  CZ3 . TRP D 1 194 ? -9.757  11.135  -38.948 1.00 29.23  ? 194 TRP D CZ3 1 
ATOM   11853 C  CH2 . TRP D 1 194 ? -10.867 11.876  -38.535 1.00 25.52  ? 194 TRP D CH2 1 
ATOM   11854 N  N   . VAL D 1 195 ? -5.211  10.917  -37.963 1.00 24.08  ? 195 VAL D N   1 
ATOM   11855 C  CA  . VAL D 1 195 ? -5.735  9.681   -37.400 1.00 23.15  ? 195 VAL D CA  1 
ATOM   11856 C  C   . VAL D 1 195 ? -5.237  9.497   -35.970 1.00 27.77  ? 195 VAL D C   1 
ATOM   11857 O  O   . VAL D 1 195 ? -5.956  8.974   -35.114 1.00 28.01  ? 195 VAL D O   1 
ATOM   11858 C  CB  . VAL D 1 195 ? -5.357  8.478   -38.286 1.00 24.18  ? 195 VAL D CB  1 
ATOM   11859 C  CG1 . VAL D 1 195 ? -5.659  7.167   -37.564 1.00 28.25  ? 195 VAL D CG1 1 
ATOM   11860 C  CG2 . VAL D 1 195 ? -6.134  8.510   -39.612 1.00 24.73  ? 195 VAL D CG2 1 
ATOM   11861 N  N   . GLU D 1 196 ? -3.993  9.907   -35.703 1.00 22.75  ? 196 GLU D N   1 
ATOM   11862 C  CA  . GLU D 1 196 ? -3.450  9.891   -34.351 1.00 31.85  ? 196 GLU D CA  1 
ATOM   11863 C  C   . GLU D 1 196 ? -4.161  10.899  -33.460 1.00 32.23  ? 196 GLU D C   1 
ATOM   11864 O  O   . GLU D 1 196 ? -4.444  10.616  -32.290 1.00 30.25  ? 196 GLU D O   1 
ATOM   11865 C  CB  . GLU D 1 196 ? -1.946  10.193  -34.398 1.00 38.69  ? 196 GLU D CB  1 
ATOM   11866 C  CG  . GLU D 1 196 ? -1.084  9.425   -33.404 1.00 42.96  ? 196 GLU D CG  1 
ATOM   11867 C  CD  . GLU D 1 196 ? 0.390   9.747   -33.573 1.00 58.04  ? 196 GLU D CD  1 
ATOM   11868 O  OE1 . GLU D 1 196 ? 0.841   10.728  -32.944 1.00 58.10  ? 196 GLU D OE1 1 
ATOM   11869 O  OE2 . GLU D 1 196 ? 1.090   9.039   -34.342 1.00 62.58  ? 196 GLU D OE2 1 
ATOM   11870 N  N   . GLN D 1 197 ? -4.449  12.083  -33.990 1.00 23.25  ? 197 GLN D N   1 
ATOM   11871 C  CA  . GLN D 1 197 ? -5.179  13.070  -33.204 1.00 30.93  ? 197 GLN D CA  1 
ATOM   11872 C  C   . GLN D 1 197 ? -6.617  12.627  -32.973 1.00 30.24  ? 197 GLN D C   1 
ATOM   11873 O  O   . GLN D 1 197 ? -7.194  12.915  -31.923 1.00 31.06  ? 197 GLN D O   1 
ATOM   11874 C  CB  . GLN D 1 197 ? -5.122  14.435  -33.896 1.00 29.04  ? 197 GLN D CB  1 
ATOM   11875 C  CG  . GLN D 1 197 ? -5.227  15.631  -32.957 1.00 41.40  ? 197 GLN D CG  1 
ATOM   11876 C  CD  . GLN D 1 197 ? -4.306  15.544  -31.721 1.00 47.10  ? 197 GLN D CD  1 
ATOM   11877 O  OE1 . GLN D 1 197 ? -3.137  15.127  -31.803 1.00 48.80  ? 197 GLN D OE1 1 
ATOM   11878 N  NE2 . GLN D 1 197 ? -4.837  15.953  -30.575 1.00 39.38  ? 197 GLN D NE2 1 
ATOM   11879 N  N   . TRP D 1 198 ? -7.201  11.902  -33.921 1.00 28.02  ? 198 TRP D N   1 
ATOM   11880 C  CA  . TRP D 1 198 ? -8.537  11.362  -33.713 1.00 26.69  ? 198 TRP D CA  1 
ATOM   11881 C  C   . TRP D 1 198 ? -8.567  10.479  -32.472 1.00 27.77  ? 198 TRP D C   1 
ATOM   11882 O  O   . TRP D 1 198 ? -9.385  10.678  -31.569 1.00 29.16  ? 198 TRP D O   1 
ATOM   11883 C  CB  . TRP D 1 198 ? -8.955  10.596  -34.965 1.00 26.83  ? 198 TRP D CB  1 
ATOM   11884 C  CG  . TRP D 1 198 ? -10.134 9.699   -34.856 1.00 27.70  ? 198 TRP D CG  1 
ATOM   11885 C  CD1 . TRP D 1 198 ? -10.109 8.344   -34.826 1.00 24.41  ? 198 TRP D CD1 1 
ATOM   11886 C  CD2 . TRP D 1 198 ? -11.524 10.078  -34.828 1.00 29.13  ? 198 TRP D CD2 1 
ATOM   11887 N  NE1 . TRP D 1 198 ? -11.380 7.851   -34.749 1.00 27.59  ? 198 TRP D NE1 1 
ATOM   11888 C  CE2 . TRP D 1 198 ? -12.271 8.892   -34.743 1.00 28.69  ? 198 TRP D CE2 1 
ATOM   11889 C  CE3 . TRP D 1 198 ? -12.200 11.299  -34.832 1.00 27.24  ? 198 TRP D CE3 1 
ATOM   11890 C  CZ2 . TRP D 1 198 ? -13.671 8.886   -34.686 1.00 28.75  ? 198 TRP D CZ2 1 
ATOM   11891 C  CZ3 . TRP D 1 198 ? -13.581 11.296  -34.785 1.00 27.42  ? 198 TRP D CZ3 1 
ATOM   11892 C  CH2 . TRP D 1 198 ? -14.306 10.092  -34.715 1.00 26.31  ? 198 TRP D CH2 1 
ATOM   11893 N  N   . PHE D 1 199 ? -7.650  9.523   -32.393 1.00 26.93  ? 199 PHE D N   1 
ATOM   11894 C  CA  . PHE D 1 199 ? -7.657  8.597   -31.268 1.00 31.63  ? 199 PHE D CA  1 
ATOM   11895 C  C   . PHE D 1 199 ? -7.244  9.272   -29.979 1.00 32.15  ? 199 PHE D C   1 
ATOM   11896 O  O   . PHE D 1 199 ? -7.736  8.897   -28.913 1.00 38.47  ? 199 PHE D O   1 
ATOM   11897 C  CB  . PHE D 1 199 ? -6.748  7.422   -31.562 1.00 30.90  ? 199 PHE D CB  1 
ATOM   11898 C  CG  . PHE D 1 199 ? -7.331  6.482   -32.540 1.00 28.88  ? 199 PHE D CG  1 
ATOM   11899 C  CD1 . PHE D 1 199 ? -8.488  5.799   -32.234 1.00 28.97  ? 199 PHE D CD1 1 
ATOM   11900 C  CD2 . PHE D 1 199 ? -6.748  6.297   -33.773 1.00 27.45  ? 199 PHE D CD2 1 
ATOM   11901 C  CE1 . PHE D 1 199 ? -9.050  4.929   -33.143 1.00 26.19  ? 199 PHE D CE1 1 
ATOM   11902 C  CE2 . PHE D 1 199 ? -7.300  5.435   -34.682 1.00 28.37  ? 199 PHE D CE2 1 
ATOM   11903 C  CZ  . PHE D 1 199 ? -8.456  4.738   -34.366 1.00 30.12  ? 199 PHE D CZ  1 
ATOM   11904 N  N   . ALA D 1 200 ? -6.348  10.257  -30.047 1.00 24.73  ? 200 ALA D N   1 
ATOM   11905 C  CA  . ALA D 1 200 ? -6.011  11.025  -28.853 1.00 30.47  ? 200 ALA D CA  1 
ATOM   11906 C  C   . ALA D 1 200 ? -7.224  11.782  -28.327 1.00 29.72  ? 200 ALA D C   1 
ATOM   11907 O  O   . ALA D 1 200 ? -7.444  11.871  -27.107 1.00 27.95  ? 200 ALA D O   1 
ATOM   11908 C  CB  . ALA D 1 200 ? -4.859  11.994  -29.154 1.00 24.68  ? 200 ALA D CB  1 
ATOM   11909 N  N   . LEU D 1 201 ? -8.010  12.358  -29.232 1.00 25.45  ? 201 LEU D N   1 
ATOM   11910 C  CA  . LEU D 1 201 ? -9.155  13.160  -28.822 1.00 27.50  ? 201 LEU D CA  1 
ATOM   11911 C  C   . LEU D 1 201 ? -10.260 12.287  -28.215 1.00 28.55  ? 201 LEU D C   1 
ATOM   11912 O  O   . LEU D 1 201 ? -10.920 12.691  -27.246 1.00 28.48  ? 201 LEU D O   1 
ATOM   11913 C  CB  . LEU D 1 201 ? -9.675  13.963  -30.022 1.00 26.11  ? 201 LEU D CB  1 
ATOM   11914 C  CG  . LEU D 1 201 ? -8.865  15.182  -30.472 1.00 28.09  ? 201 LEU D CG  1 
ATOM   11915 C  CD1 . LEU D 1 201 ? -9.508  15.782  -31.710 1.00 25.83  ? 201 LEU D CD1 1 
ATOM   11916 C  CD2 . LEU D 1 201 ? -8.826  16.206  -29.349 1.00 24.94  ? 201 LEU D CD2 1 
ATOM   11917 N  N   . LEU D 1 202 ? -10.506 11.111  -28.795 1.00 19.87  ? 202 LEU D N   1 
ATOM   11918 C  CA  . LEU D 1 202 ? -11.483 10.198  -28.215 1.00 29.23  ? 202 LEU D CA  1 
ATOM   11919 C  C   . LEU D 1 202 ? -11.101 9.808   -26.786 1.00 31.77  ? 202 LEU D C   1 
ATOM   11920 O  O   . LEU D 1 202 ? -11.963 9.746   -25.898 1.00 35.17  ? 202 LEU D O   1 
ATOM   11921 C  CB  . LEU D 1 202 ? -11.601 8.955   -29.090 1.00 30.22  ? 202 LEU D CB  1 
ATOM   11922 C  CG  . LEU D 1 202 ? -12.163 9.232   -30.478 1.00 28.98  ? 202 LEU D CG  1 
ATOM   11923 C  CD1 . LEU D 1 202 ? -11.983 7.981   -31.356 1.00 24.06  ? 202 LEU D CD1 1 
ATOM   11924 C  CD2 . LEU D 1 202 ? -13.616 9.649   -30.358 1.00 24.71  ? 202 LEU D CD2 1 
ATOM   11925 N  N   . SER D 1 203 ? -9.813  9.542   -26.553 1.00 31.24  ? 203 SER D N   1 
ATOM   11926 C  CA  . SER D 1 203 ? -9.326  9.215   -25.216 1.00 28.94  ? 203 SER D CA  1 
ATOM   11927 C  C   . SER D 1 203 ? -9.513  10.391  -24.280 1.00 35.00  ? 203 SER D C   1 
ATOM   11928 O  O   . SER D 1 203 ? -10.015 10.237  -23.164 1.00 34.06  ? 203 SER D O   1 
ATOM   11929 C  CB  . SER D 1 203 ? -7.849  8.799   -25.290 1.00 30.15  ? 203 SER D CB  1 
ATOM   11930 O  OG  . SER D 1 203 ? -7.236  8.740   -24.007 1.00 33.58  ? 203 SER D OG  1 
ATOM   11931 N  N   . THR D 1 204 ? -9.146  11.585  -24.743 1.00 28.12  ? 204 THR D N   1 
ATOM   11932 C  CA  . THR D 1 204 ? -9.233  12.784  -23.924 1.00 31.85  ? 204 THR D CA  1 
ATOM   11933 C  C   . THR D 1 204 ? -10.663 13.067  -23.497 1.00 34.96  ? 204 THR D C   1 
ATOM   11934 O  O   . THR D 1 204 ? -10.927 13.362  -22.327 1.00 40.91  ? 204 THR D O   1 
ATOM   11935 C  CB  . THR D 1 204 ? -8.673  13.967  -24.705 1.00 27.72  ? 204 THR D CB  1 
ATOM   11936 O  OG1 . THR D 1 204 ? -7.243  13.898  -24.685 1.00 32.62  ? 204 THR D OG1 1 
ATOM   11937 C  CG2 . THR D 1 204 ? -9.141  15.269  -24.110 1.00 27.57  ? 204 THR D CG2 1 
ATOM   11938 N  N   . TYR D 1 205 ? -11.602 13.013  -24.436 1.00 33.74  ? 205 TYR D N   1 
ATOM   11939 C  CA  . TYR D 1 205 ? -12.979 13.336  -24.118 1.00 28.45  ? 205 TYR D CA  1 
ATOM   11940 C  C   . TYR D 1 205 ? -13.797 12.103  -23.790 1.00 24.94  ? 205 TYR D C   1 
ATOM   11941 O  O   . TYR D 1 205 ? -15.002 12.213  -23.591 1.00 25.54  ? 205 TYR D O   1 
ATOM   11942 C  CB  . TYR D 1 205 ? -13.608 14.146  -25.250 1.00 29.42  ? 205 TYR D CB  1 
ATOM   11943 C  CG  . TYR D 1 205 ? -12.976 15.514  -25.329 1.00 25.55  ? 205 TYR D CG  1 
ATOM   11944 C  CD1 . TYR D 1 205 ? -13.295 16.494  -24.402 1.00 27.99  ? 205 TYR D CD1 1 
ATOM   11945 C  CD2 . TYR D 1 205 ? -12.008 15.798  -26.279 1.00 26.82  ? 205 TYR D CD2 1 
ATOM   11946 C  CE1 . TYR D 1 205 ? -12.700 17.738  -24.433 1.00 25.24  ? 205 TYR D CE1 1 
ATOM   11947 C  CE2 . TYR D 1 205 ? -11.409 17.040  -26.323 1.00 25.80  ? 205 TYR D CE2 1 
ATOM   11948 C  CZ  . TYR D 1 205 ? -11.751 18.003  -25.400 1.00 30.01  ? 205 TYR D CZ  1 
ATOM   11949 O  OH  . TYR D 1 205 ? -11.151 19.240  -25.447 1.00 34.10  ? 205 TYR D OH  1 
ATOM   11950 N  N   . GLY D 1 206 ? -13.163 10.940  -23.708 1.00 30.07  ? 206 GLY D N   1 
ATOM   11951 C  CA  . GLY D 1 206 ? -13.854 9.753   -23.226 1.00 34.12  ? 206 GLY D CA  1 
ATOM   11952 C  C   . GLY D 1 206 ? -15.005 9.325   -24.104 1.00 35.52  ? 206 GLY D C   1 
ATOM   11953 O  O   . GLY D 1 206 ? -16.029 8.867   -23.589 1.00 29.40  ? 206 GLY D O   1 
ATOM   11954 N  N   . LEU D 1 207 ? -14.857 9.455   -25.426 1.00 30.54  ? 207 LEU D N   1 
ATOM   11955 C  CA  . LEU D 1 207 ? -15.871 9.039   -26.388 1.00 31.32  ? 207 LEU D CA  1 
ATOM   11956 C  C   . LEU D 1 207 ? -15.428 7.777   -27.123 1.00 27.54  ? 207 LEU D C   1 
ATOM   11957 O  O   . LEU D 1 207 ? -14.239 7.475   -27.212 1.00 28.28  ? 207 LEU D O   1 
ATOM   11958 C  CB  . LEU D 1 207 ? -16.153 10.172  -27.399 1.00 29.27  ? 207 LEU D CB  1 
ATOM   11959 C  CG  . LEU D 1 207 ? -16.413 11.522  -26.723 1.00 31.46  ? 207 LEU D CG  1 
ATOM   11960 C  CD1 . LEU D 1 207 ? -16.266 12.714  -27.698 1.00 27.69  ? 207 LEU D CD1 1 
ATOM   11961 C  CD2 . LEU D 1 207 ? -17.772 11.522  -26.037 1.00 31.07  ? 207 LEU D CD2 1 
ATOM   11962 N  N   . GLU D 1 208 ? -16.400 7.074   -27.701 1.00 26.67  ? 208 GLU D N   1 
ATOM   11963 C  CA  . GLU D 1 208 ? -16.106 5.878   -28.527 1.00 27.61  ? 208 GLU D CA  1 
ATOM   11964 C  C   . GLU D 1 208 ? -16.740 6.067   -29.902 1.00 31.73  ? 208 GLU D C   1 
ATOM   11965 O  O   . GLU D 1 208 ? -17.848 6.608   -29.975 1.00 32.20  ? 208 GLU D O   1 
ATOM   11966 C  CB  . GLU D 1 208 ? -16.659 4.600   -27.901 1.00 30.85  ? 208 GLU D CB  1 
ATOM   11967 C  CG  . GLU D 1 208 ? -18.151 4.626   -27.649 1.00 35.79  ? 208 GLU D CG  1 
ATOM   11968 C  CD  . GLU D 1 208 ? -18.676 3.410   -26.906 1.00 45.27  ? 208 GLU D CD  1 
ATOM   11969 O  OE1 . GLU D 1 208 ? -18.379 3.284   -25.704 1.00 47.92  ? 208 GLU D OE1 1 
ATOM   11970 O  OE2 . GLU D 1 208 ? -19.384 2.603   -27.528 1.00 40.74  ? 208 GLU D OE2 1 
ATOM   11971 N  N   . PRO D 1 209 ? -16.077 5.657   -30.995 1.00 31.10  ? 209 PRO D N   1 
ATOM   11972 C  CA  . PRO D 1 209 ? -16.704 5.730   -32.309 1.00 33.25  ? 209 PRO D CA  1 
ATOM   11973 C  C   . PRO D 1 209 ? -17.904 4.774   -32.423 1.00 34.56  ? 209 PRO D C   1 
ATOM   11974 O  O   . PRO D 1 209 ? -17.750 3.621   -32.135 1.00 35.49  ? 209 PRO D O   1 
ATOM   11975 C  CB  . PRO D 1 209 ? -15.569 5.302   -33.245 1.00 30.99  ? 209 PRO D CB  1 
ATOM   11976 C  CG  . PRO D 1 209 ? -14.315 5.534   -32.445 1.00 30.30  ? 209 PRO D CG  1 
ATOM   11977 C  CD  . PRO D 1 209 ? -14.705 5.170   -31.031 1.00 28.44  ? 209 PRO D CD  1 
ATOM   11978 N  N   . THR D 1 210 ? -19.046 5.271   -32.894 1.00 31.29  ? 210 THR D N   1 
ATOM   11979 C  CA  . THR D 1 210 ? -20.269 4.435   -33.041 1.00 34.10  ? 210 THR D CA  1 
ATOM   11980 C  C   . THR D 1 210 ? -20.578 4.047   -34.490 1.00 32.80  ? 210 THR D C   1 
ATOM   11981 O  O   . THR D 1 210 ? -20.168 2.960   -34.903 1.00 36.49  ? 210 THR D O   1 
ATOM   11982 C  CB  . THR D 1 210 ? -21.482 5.115   -32.393 1.00 29.20  ? 210 THR D CB  1 
ATOM   11983 O  OG1 . THR D 1 210 ? -21.687 6.394   -32.988 1.00 31.19  ? 210 THR D OG1 1 
ATOM   11984 C  CG2 . THR D 1 210 ? -21.319 5.272   -30.899 1.00 28.42  ? 210 THR D CG2 1 
ATOM   11985 N  N   . ASN D 1 211 ? -21.248 4.928   -35.223 1.00 32.23  ? 211 ASN D N   1 
ATOM   11986 C  CA  . ASN D 1 211 ? -21.577 4.670   -36.643 1.00 29.27  ? 211 ASN D CA  1 
ATOM   11987 C  C   . ASN D 1 211 ? -20.954 5.732   -37.548 1.00 31.14  ? 211 ASN D C   1 
ATOM   11988 O  O   . ASN D 1 211 ? -20.855 6.892   -37.143 1.00 28.38  ? 211 ASN D O   1 
ATOM   11989 C  CB  . ASN D 1 211 ? -23.084 4.618   -36.888 1.00 32.84  ? 211 ASN D CB  1 
ATOM   11990 C  CG  . ASN D 1 211 ? -23.480 4.584   -38.345 1.00 36.06  ? 211 ASN D CG  1 
ATOM   11991 O  OD1 . ASN D 1 211 ? -23.368 3.552   -39.000 1.00 36.38  ? 211 ASN D OD1 1 
ATOM   11992 N  ND2 . ASN D 1 211 ? -23.961 5.706   -38.850 1.00 35.34  ? 211 ASN D ND2 1 
ATOM   11993 N  N   . MET D 1 212 ? -20.513 5.311   -38.716 1.00 28.58  ? 212 MET D N   1 
ATOM   11994 C  CA  . MET D 1 212 ? -20.042 6.240   -39.735 1.00 31.46  ? 212 MET D CA  1 
ATOM   11995 C  C   . MET D 1 212 ? -20.919 6.082   -40.970 1.00 35.00  ? 212 MET D C   1 
ATOM   11996 O  O   . MET D 1 212 ? -20.891 5.041   -41.642 1.00 38.54  ? 212 MET D O   1 
ATOM   11997 C  CB  . MET D 1 212 ? -18.561 6.030   -40.059 1.00 28.68  ? 212 MET D CB  1 
ATOM   11998 C  CG  . MET D 1 212 ? -18.034 6.892   -41.232 1.00 30.42  ? 212 MET D CG  1 
ATOM   11999 S  SD  . MET D 1 212 ? -16.370 6.394   -41.752 1.00 32.12  ? 212 MET D SD  1 
ATOM   12000 C  CE  . MET D 1 212 ? -16.726 5.396   -43.209 1.00 24.12  ? 212 MET D CE  1 
ATOM   12001 N  N   . GLY D 1 213 ? -21.708 7.114   -41.248 1.00 36.05  ? 213 GLY D N   1 
ATOM   12002 C  CA  . GLY D 1 213 ? -22.469 7.136   -42.484 1.00 36.90  ? 213 GLY D CA  1 
ATOM   12003 C  C   . GLY D 1 213 ? -21.559 7.163   -43.702 1.00 35.49  ? 213 GLY D C   1 
ATOM   12004 O  O   . GLY D 1 213 ? -20.479 7.755   -43.691 1.00 33.03  ? 213 GLY D O   1 
ATOM   12005 N  N   . SER D 1 214 ? -21.992 6.481   -44.750 1.00 33.31  ? 214 SER D N   1 
ATOM   12006 C  CA  . SER D 1 214 ? -21.305 6.481   -46.024 1.00 34.24  ? 214 SER D CA  1 
ATOM   12007 C  C   . SER D 1 214 ? -22.365 6.571   -47.110 1.00 29.09  ? 214 SER D C   1 
ATOM   12008 O  O   . SER D 1 214 ? -23.565 6.635   -46.825 1.00 31.60  ? 214 SER D O   1 
ATOM   12009 C  CB  . SER D 1 214 ? -20.414 5.248   -46.152 1.00 34.48  ? 214 SER D CB  1 
ATOM   12010 O  OG  . SER D 1 214 ? -21.189 4.085   -46.360 1.00 33.20  ? 214 SER D OG  1 
ATOM   12011 N  N   . TRP D 1 215 ? -21.921 6.613   -48.366 1.00 35.33  ? 215 TRP D N   1 
ATOM   12012 C  CA  . TRP D 1 215 ? -22.832 6.756   -49.496 1.00 35.67  ? 215 TRP D CA  1 
ATOM   12013 C  C   . TRP D 1 215 ? -22.462 5.776   -50.601 1.00 33.38  ? 215 TRP D C   1 
ATOM   12014 O  O   . TRP D 1 215 ? -21.290 5.426   -50.786 1.00 32.15  ? 215 TRP D O   1 
ATOM   12015 C  CB  . TRP D 1 215 ? -22.829 8.193   -50.063 1.00 30.47  ? 215 TRP D CB  1 
ATOM   12016 C  CG  . TRP D 1 215 ? -23.557 9.136   -49.211 1.00 27.88  ? 215 TRP D CG  1 
ATOM   12017 C  CD1 . TRP D 1 215 ? -24.856 9.527   -49.343 1.00 33.33  ? 215 TRP D CD1 1 
ATOM   12018 C  CD2 . TRP D 1 215 ? -23.048 9.809   -48.049 1.00 29.42  ? 215 TRP D CD2 1 
ATOM   12019 N  NE1 . TRP D 1 215 ? -25.192 10.411  -48.328 1.00 30.29  ? 215 TRP D NE1 1 
ATOM   12020 C  CE2 . TRP D 1 215 ? -24.097 10.595  -47.523 1.00 27.16  ? 215 TRP D CE2 1 
ATOM   12021 C  CE3 . TRP D 1 215 ? -21.805 9.830   -47.409 1.00 27.98  ? 215 TRP D CE3 1 
ATOM   12022 C  CZ2 . TRP D 1 215 ? -23.937 11.393  -46.390 1.00 30.99  ? 215 TRP D CZ2 1 
ATOM   12023 C  CZ3 . TRP D 1 215 ? -21.649 10.625  -46.284 1.00 28.20  ? 215 TRP D CZ3 1 
ATOM   12024 C  CH2 . TRP D 1 215 ? -22.713 11.387  -45.781 1.00 29.09  ? 215 TRP D CH2 1 
ATOM   12025 N  N   . ILE D 1 216 ? -23.495 5.317   -51.310 1.00 34.42  ? 216 ILE D N   1 
ATOM   12026 C  CA  . ILE D 1 216 ? -23.365 4.602   -52.574 1.00 30.58  ? 216 ILE D CA  1 
ATOM   12027 C  C   . ILE D 1 216 ? -23.979 5.518   -53.612 1.00 30.09  ? 216 ILE D C   1 
ATOM   12028 O  O   . ILE D 1 216 ? -25.188 5.467   -53.867 1.00 29.87  ? 216 ILE D O   1 
ATOM   12029 C  CB  . ILE D 1 216 ? -24.067 3.233   -52.586 1.00 36.46  ? 216 ILE D CB  1 
ATOM   12030 C  CG1 . ILE D 1 216 ? -23.906 2.471   -51.256 1.00 34.66  ? 216 ILE D CG1 1 
ATOM   12031 C  CG2 . ILE D 1 216 ? -23.552 2.403   -53.770 1.00 32.44  ? 216 ILE D CG2 1 
ATOM   12032 C  CD1 . ILE D 1 216 ? -22.468 2.232   -50.835 1.00 35.41  ? 216 ILE D CD1 1 
ATOM   12033 N  N   . ASP D 1 217 ? -23.142 6.365   -54.208 1.00 28.43  ? 217 ASP D N   1 
ATOM   12034 C  CA  . ASP D 1 217 ? -23.587 7.439   -55.091 1.00 31.71  ? 217 ASP D CA  1 
ATOM   12035 C  C   . ASP D 1 217 ? -23.875 6.890   -56.487 1.00 32.33  ? 217 ASP D C   1 
ATOM   12036 O  O   . ASP D 1 217 ? -23.126 7.108   -57.442 1.00 31.45  ? 217 ASP D O   1 
ATOM   12037 C  CB  . ASP D 1 217 ? -22.530 8.533   -55.139 1.00 31.13  ? 217 ASP D CB  1 
ATOM   12038 C  CG  . ASP D 1 217 ? -22.391 9.264   -53.818 1.00 32.53  ? 217 ASP D CG  1 
ATOM   12039 O  OD1 . ASP D 1 217 ? -23.414 9.798   -53.327 1.00 32.31  ? 217 ASP D OD1 1 
ATOM   12040 O  OD2 . ASP D 1 217 ? -21.267 9.316   -53.272 1.00 32.51  ? 217 ASP D OD2 1 
ATOM   12041 N  N   . THR D 1 218 ? -25.026 6.212   -56.602 1.00 28.66  ? 218 THR D N   1 
ATOM   12042 C  CA  . THR D 1 218 ? -25.399 5.581   -57.869 1.00 31.33  ? 218 THR D CA  1 
ATOM   12043 C  C   . THR D 1 218 ? -25.392 6.566   -59.039 1.00 32.82  ? 218 THR D C   1 
ATOM   12044 O  O   . THR D 1 218 ? -25.137 6.169   -60.182 1.00 30.23  ? 218 THR D O   1 
ATOM   12045 C  CB  . THR D 1 218 ? -26.788 4.939   -57.757 1.00 33.43  ? 218 THR D CB  1 
ATOM   12046 O  OG1 . THR D 1 218 ? -27.701 5.880   -57.183 1.00 38.85  ? 218 THR D OG1 1 
ATOM   12047 C  CG2 . THR D 1 218 ? -26.750 3.717   -56.889 1.00 32.50  ? 218 THR D CG2 1 
ATOM   12048 N  N   . ARG D 1 219 ? -25.685 7.841   -58.786 1.00 32.08  ? 219 ARG D N   1 
ATOM   12049 C  CA  . ARG D 1 219 ? -25.751 8.831   -59.850 1.00 32.52  ? 219 ARG D CA  1 
ATOM   12050 C  C   . ARG D 1 219 ? -24.403 9.514   -60.084 1.00 33.26  ? 219 ARG D C   1 
ATOM   12051 O  O   . ARG D 1 219 ? -24.359 10.617  -60.648 1.00 29.85  ? 219 ARG D O   1 
ATOM   12052 C  CB  . ARG D 1 219 ? -26.836 9.867   -59.546 1.00 32.06  ? 219 ARG D CB  1 
ATOM   12053 C  CG  . ARG D 1 219 ? -28.209 9.278   -59.357 1.00 36.06  ? 219 ARG D CG  1 
ATOM   12054 C  CD  . ARG D 1 219 ? -29.317 10.290  -59.585 1.00 38.70  ? 219 ARG D CD  1 
ATOM   12055 N  NE  . ARG D 1 219 ? -30.631 9.668   -59.441 1.00 50.10  ? 219 ARG D NE  1 
ATOM   12056 C  CZ  . ARG D 1 219 ? -31.476 9.903   -58.443 1.00 52.31  ? 219 ARG D CZ  1 
ATOM   12057 N  NH1 . ARG D 1 219 ? -31.259 10.870  -57.567 1.00 51.76  ? 219 ARG D NH1 1 
ATOM   12058 N  NH2 . ARG D 1 219 ? -32.572 9.155   -58.327 1.00 50.98  ? 219 ARG D NH2 1 
ATOM   12059 N  N   . LEU D 1 220 ? -23.316 8.850   -59.683 1.00 31.17  ? 220 LEU D N   1 
ATOM   12060 C  CA  . LEU D 1 220 ? -21.973 9.412   -59.757 1.00 30.92  ? 220 LEU D CA  1 
ATOM   12061 C  C   . LEU D 1 220 ? -21.691 10.047  -61.109 1.00 33.36  ? 220 LEU D C   1 
ATOM   12062 O  O   . LEU D 1 220 ? -21.278 11.211  -61.183 1.00 34.71  ? 220 LEU D O   1 
ATOM   12063 C  CB  . LEU D 1 220 ? -20.943 8.321   -59.465 1.00 28.27  ? 220 LEU D CB  1 
ATOM   12064 C  CG  . LEU D 1 220 ? -19.573 8.900   -59.128 1.00 26.08  ? 220 LEU D CG  1 
ATOM   12065 C  CD1 . LEU D 1 220 ? -19.706 9.811   -57.904 1.00 29.18  ? 220 LEU D CD1 1 
ATOM   12066 C  CD2 . LEU D 1 220 ? -18.558 7.820   -58.878 1.00 26.08  ? 220 LEU D CD2 1 
ATOM   12067 N  N   . HIS D 1 221 ? -21.899 9.291   -62.193 1.00 35.96  ? 221 HIS D N   1 
ATOM   12068 C  CA  . HIS D 1 221 ? -21.663 9.783   -63.542 1.00 34.32  ? 221 HIS D CA  1 
ATOM   12069 C  C   . HIS D 1 221 ? -22.937 9.777   -64.369 1.00 38.90  ? 221 HIS D C   1 
ATOM   12070 O  O   . HIS D 1 221 ? -22.961 9.210   -65.468 1.00 36.19  ? 221 HIS D O   1 
ATOM   12071 C  CB  . HIS D 1 221 ? -20.610 8.941   -64.257 1.00 38.55  ? 221 HIS D CB  1 
ATOM   12072 C  CG  . HIS D 1 221 ? -19.272 8.954   -63.596 1.00 39.94  ? 221 HIS D CG  1 
ATOM   12073 N  ND1 . HIS D 1 221 ? -18.888 8.000   -62.680 1.00 36.89  ? 221 HIS D ND1 1 
ATOM   12074 C  CD2 . HIS D 1 221 ? -18.213 9.788   -63.738 1.00 37.17  ? 221 HIS D CD2 1 
ATOM   12075 C  CE1 . HIS D 1 221 ? -17.656 8.252   -62.275 1.00 39.91  ? 221 HIS D CE1 1 
ATOM   12076 N  NE2 . HIS D 1 221 ? -17.224 9.332   -62.900 1.00 39.49  ? 221 HIS D NE2 1 
ATOM   12077 N  N   . SER D 1 222 ? -23.991 10.406  -63.860 1.00 34.23  ? 222 SER D N   1 
ATOM   12078 C  CA  . SER D 1 222 ? -25.276 10.408  -64.544 1.00 37.27  ? 222 SER D CA  1 
ATOM   12079 C  C   . SER D 1 222 ? -25.430 11.552  -65.532 1.00 42.19  ? 222 SER D C   1 
ATOM   12080 O  O   . SER D 1 222 ? -26.259 11.450  -66.444 1.00 46.53  ? 222 SER D O   1 
ATOM   12081 C  CB  . SER D 1 222 ? -26.412 10.494  -63.532 1.00 33.06  ? 222 SER D CB  1 
ATOM   12082 O  OG  . SER D 1 222 ? -26.501 11.823  -63.036 1.00 36.36  ? 222 SER D OG  1 
ATOM   12083 N  N   . SER D 1 223 ? -24.663 12.626  -65.370 1.00 40.20  ? 223 SER D N   1 
ATOM   12084 C  CA  . SER D 1 223 ? -24.764 13.823  -66.186 1.00 37.51  ? 223 SER D CA  1 
ATOM   12085 C  C   . SER D 1 223 ? -23.791 13.755  -67.358 1.00 35.14  ? 223 SER D C   1 
ATOM   12086 O  O   . SER D 1 223 ? -22.832 12.982  -67.349 1.00 36.80  ? 223 SER D O   1 
ATOM   12087 C  CB  . SER D 1 223 ? -24.472 15.067  -65.335 1.00 35.20  ? 223 SER D CB  1 
ATOM   12088 O  OG  . SER D 1 223 ? -25.570 15.416  -64.511 1.00 32.32  ? 223 SER D OG  1 
ATOM   12089 N  N   . GLY D 1 224 ? -24.046 14.586  -68.374 1.00 39.93  ? 224 GLY D N   1 
ATOM   12090 C  CA  . GLY D 1 224 ? -23.123 14.753  -69.481 1.00 41.28  ? 224 GLY D CA  1 
ATOM   12091 C  C   . GLY D 1 224 ? -23.274 13.749  -70.616 1.00 43.81  ? 224 GLY D C   1 
ATOM   12092 O  O   . GLY D 1 224 ? -24.068 12.806  -70.552 1.00 41.89  ? 224 GLY D O   1 
ATOM   12093 N  N   . PRO D 1 225 ? -22.491 13.938  -71.684 1.00 49.17  ? 225 PRO D N   1 
ATOM   12094 C  CA  . PRO D 1 225 ? -22.650 13.083  -72.869 1.00 47.20  ? 225 PRO D CA  1 
ATOM   12095 C  C   . PRO D 1 225 ? -22.181 11.664  -72.650 1.00 48.74  ? 225 PRO D C   1 
ATOM   12096 O  O   . PRO D 1 225 ? -22.688 10.743  -73.303 1.00 48.16  ? 225 PRO D O   1 
ATOM   12097 C  CB  . PRO D 1 225 ? -21.789 13.789  -73.926 1.00 47.15  ? 225 PRO D CB  1 
ATOM   12098 C  CG  . PRO D 1 225 ? -21.524 15.147  -73.377 1.00 50.98  ? 225 PRO D CG  1 
ATOM   12099 C  CD  . PRO D 1 225 ? -21.461 14.964  -71.900 1.00 50.58  ? 225 PRO D CD  1 
ATOM   12100 N  N   . ASN D 1 226 ? -21.208 11.454  -71.770 1.00 47.57  ? 226 ASN D N   1 
ATOM   12101 C  CA  . ASN D 1 226 ? -20.687 10.117  -71.511 1.00 47.69  ? 226 ASN D CA  1 
ATOM   12102 C  C   . ASN D 1 226 ? -21.286 9.524   -70.239 1.00 50.97  ? 226 ASN D C   1 
ATOM   12103 O  O   . ASN D 1 226 ? -20.590 8.890   -69.441 1.00 49.29  ? 226 ASN D O   1 
ATOM   12104 C  CB  . ASN D 1 226 ? -19.163 10.150  -71.446 1.00 47.89  ? 226 ASN D CB  1 
ATOM   12105 C  CG  . ASN D 1 226 ? -18.520 9.461   -72.642 1.00 55.42  ? 226 ASN D CG  1 
ATOM   12106 O  OD1 . ASN D 1 226 ? -19.208 9.106   -73.601 1.00 57.77  ? 226 ASN D OD1 1 
ATOM   12107 N  ND2 . ASN D 1 226 ? -17.202 9.263   -72.590 1.00 53.71  ? 226 ASN D ND2 1 
ATOM   12108 N  N   . GLY D 1 227 ? -22.587 9.718   -70.031 1.00 46.32  ? 227 GLY D N   1 
ATOM   12109 C  CA  . GLY D 1 227 ? -23.211 9.253   -68.812 1.00 43.30  ? 227 GLY D CA  1 
ATOM   12110 C  C   . GLY D 1 227 ? -23.300 7.741   -68.757 1.00 47.71  ? 227 GLY D C   1 
ATOM   12111 O  O   . GLY D 1 227 ? -23.479 7.066   -69.771 1.00 47.38  ? 227 GLY D O   1 
ATOM   12112 N  N   . ARG D 1 228 ? -23.169 7.215   -67.537 1.00 48.24  ? 228 ARG D N   1 
ATOM   12113 C  CA  . ARG D 1 228 ? -23.189 5.783   -67.266 1.00 45.56  ? 228 ARG D CA  1 
ATOM   12114 C  C   . ARG D 1 228 ? -23.727 5.562   -65.867 1.00 45.75  ? 228 ARG D C   1 
ATOM   12115 O  O   . ARG D 1 228 ? -23.672 6.450   -65.010 1.00 45.76  ? 228 ARG D O   1 
ATOM   12116 C  CB  . ARG D 1 228 ? -21.792 5.154   -67.351 1.00 46.25  ? 228 ARG D CB  1 
ATOM   12117 C  CG  . ARG D 1 228 ? -20.782 5.834   -66.434 1.00 43.86  ? 228 ARG D CG  1 
ATOM   12118 C  CD  . ARG D 1 228 ? -19.380 5.340   -66.685 1.00 42.84  ? 228 ARG D CD  1 
ATOM   12119 N  NE  . ARG D 1 228 ? -18.483 5.498   -65.544 1.00 42.84  ? 228 ARG D NE  1 
ATOM   12120 C  CZ  . ARG D 1 228 ? -18.501 4.741   -64.453 1.00 43.71  ? 228 ARG D CZ  1 
ATOM   12121 N  NH1 . ARG D 1 228 ? -19.449 3.831   -64.249 1.00 40.47  ? 228 ARG D NH1 1 
ATOM   12122 N  NH2 . ARG D 1 228 ? -17.553 4.904   -63.535 1.00 43.83  ? 228 ARG D NH2 1 
ATOM   12123 N  N   . ASP D 1 229 ? -24.215 4.353   -65.634 1.00 46.67  ? 229 ASP D N   1 
ATOM   12124 C  CA  . ASP D 1 229 ? -24.696 3.967   -64.322 1.00 40.20  ? 229 ASP D CA  1 
ATOM   12125 C  C   . ASP D 1 229 ? -23.557 3.368   -63.507 1.00 36.77  ? 229 ASP D C   1 
ATOM   12126 O  O   . ASP D 1 229 ? -22.493 3.052   -64.033 1.00 39.69  ? 229 ASP D O   1 
ATOM   12127 C  CB  . ASP D 1 229 ? -25.846 2.977   -64.451 1.00 50.92  ? 229 ASP D CB  1 
ATOM   12128 C  CG  . ASP D 1 229 ? -27.190 3.646   -64.316 1.00 59.61  ? 229 ASP D CG  1 
ATOM   12129 O  OD1 . ASP D 1 229 ? -27.336 4.765   -64.861 1.00 55.59  ? 229 ASP D OD1 1 
ATOM   12130 O  OD2 . ASP D 1 229 ? -28.083 3.072   -63.651 1.00 60.45  ? 229 ASP D OD2 1 
ATOM   12131 N  N   . MET D 1 230 ? -23.783 3.259   -62.197 1.00 34.85  ? 230 MET D N   1 
ATOM   12132 C  CA  . MET D 1 230 ? -22.846 2.626   -61.269 1.00 32.96  ? 230 MET D CA  1 
ATOM   12133 C  C   . MET D 1 230 ? -22.957 1.107   -61.351 1.00 35.98  ? 230 MET D C   1 
ATOM   12134 O  O   . MET D 1 230 ? -24.036 0.562   -61.112 1.00 34.11  ? 230 MET D O   1 
ATOM   12135 C  CB  . MET D 1 230 ? -23.142 3.067   -59.836 1.00 31.83  ? 230 MET D CB  1 
ATOM   12136 C  CG  . MET D 1 230 ? -22.200 2.446   -58.836 1.00 31.06  ? 230 MET D CG  1 
ATOM   12137 S  SD  . MET D 1 230 ? -22.143 3.338   -57.303 1.00 40.83  ? 230 MET D SD  1 
ATOM   12138 C  CE  . MET D 1 230 ? -20.626 4.264   -57.528 1.00 32.15  ? 230 MET D CE  1 
ATOM   12139 N  N   . THR D 1 231 ? -21.847 0.420   -61.639 1.00 35.71  ? 231 THR D N   1 
ATOM   12140 C  CA  . THR D 1 231 ? -21.882 -1.041  -61.680 1.00 39.43  ? 231 THR D CA  1 
ATOM   12141 C  C   . THR D 1 231 ? -21.820 -1.636  -60.266 1.00 36.05  ? 231 THR D C   1 
ATOM   12142 O  O   . THR D 1 231 ? -21.410 -0.981  -59.301 1.00 36.40  ? 231 THR D O   1 
ATOM   12143 C  CB  . THR D 1 231 ? -20.737 -1.609  -62.525 1.00 31.15  ? 231 THR D CB  1 
ATOM   12144 O  OG1 . THR D 1 231 ? -19.503 -1.521  -61.798 1.00 33.22  ? 231 THR D OG1 1 
ATOM   12145 C  CG2 . THR D 1 231 ? -20.617 -0.861  -63.835 1.00 39.34  ? 231 THR D CG2 1 
ATOM   12146 N  N   . VAL D 1 232 ? -22.231 -2.904  -60.159 1.00 37.67  ? 232 VAL D N   1 
ATOM   12147 C  CA  . VAL D 1 232 ? -22.193 -3.599  -58.872 1.00 38.32  ? 232 VAL D CA  1 
ATOM   12148 C  C   . VAL D 1 232 ? -20.772 -3.648  -58.322 1.00 34.53  ? 232 VAL D C   1 
ATOM   12149 O  O   . VAL D 1 232 ? -20.543 -3.424  -57.125 1.00 37.15  ? 232 VAL D O   1 
ATOM   12150 C  CB  . VAL D 1 232 ? -22.793 -5.007  -59.011 1.00 40.41  ? 232 VAL D CB  1 
ATOM   12151 C  CG1 . VAL D 1 232 ? -22.340 -5.884  -57.852 1.00 42.25  ? 232 VAL D CG1 1 
ATOM   12152 C  CG2 . VAL D 1 232 ? -24.313 -4.917  -59.072 1.00 36.79  ? 232 VAL D CG2 1 
ATOM   12153 N  N   . GLU D 1 233 ? -19.794 -3.918  -59.187 1.00 35.03  ? 233 GLU D N   1 
ATOM   12154 C  CA  . GLU D 1 233 ? -18.408 -3.966  -58.731 1.00 36.55  ? 233 GLU D CA  1 
ATOM   12155 C  C   . GLU D 1 233 ? -17.929 -2.606  -58.239 1.00 35.45  ? 233 GLU D C   1 
ATOM   12156 O  O   . GLU D 1 233 ? -17.075 -2.542  -57.355 1.00 32.96  ? 233 GLU D O   1 
ATOM   12157 C  CB  . GLU D 1 233 ? -17.501 -4.484  -59.849 1.00 34.87  ? 233 GLU D CB  1 
ATOM   12158 C  CG  . GLU D 1 233 ? -17.728 -5.958  -60.180 1.00 36.73  ? 233 GLU D CG  1 
ATOM   12159 C  CD  . GLU D 1 233 ? -18.979 -6.179  -61.011 1.00 37.88  ? 233 GLU D CD  1 
ATOM   12160 O  OE1 . GLU D 1 233 ? -19.313 -5.301  -61.846 1.00 36.96  ? 233 GLU D OE1 1 
ATOM   12161 O  OE2 . GLU D 1 233 ? -19.646 -7.213  -60.795 1.00 37.08  ? 233 GLU D OE2 1 
ATOM   12162 N  N   . GLU D 1 234 ? -18.467 -1.514  -58.790 1.00 35.21  ? 234 GLU D N   1 
ATOM   12163 C  CA  . GLU D 1 234 ? -18.059 -0.185  -58.357 1.00 33.36  ? 234 GLU D CA  1 
ATOM   12164 C  C   . GLU D 1 234 ? -18.706 0.200   -57.027 1.00 33.54  ? 234 GLU D C   1 
ATOM   12165 O  O   . GLU D 1 234 ? -18.028 0.727   -56.135 1.00 32.19  ? 234 GLU D O   1 
ATOM   12166 C  CB  . GLU D 1 234 ? -18.387 0.834   -59.452 1.00 33.38  ? 234 GLU D CB  1 
ATOM   12167 C  CG  . GLU D 1 234 ? -17.282 0.961   -60.539 1.00 34.31  ? 234 GLU D CG  1 
ATOM   12168 C  CD  . GLU D 1 234 ? -17.807 1.486   -61.870 1.00 36.01  ? 234 GLU D CD  1 
ATOM   12169 O  OE1 . GLU D 1 234 ? -18.974 1.932   -61.926 1.00 35.66  ? 234 GLU D OE1 1 
ATOM   12170 O  OE2 . GLU D 1 234 ? -17.056 1.440   -62.866 1.00 37.74  ? 234 GLU D OE2 1 
ATOM   12171 N  N   . GLY D 1 235 ? -20.009 -0.057  -56.870 1.00 33.60  ? 235 GLY D N   1 
ATOM   12172 C  CA  . GLY D 1 235 ? -20.664 0.259   -55.611 1.00 32.04  ? 235 GLY D CA  1 
ATOM   12173 C  C   . GLY D 1 235 ? -20.098 -0.525  -54.440 1.00 32.74  ? 235 GLY D C   1 
ATOM   12174 O  O   . GLY D 1 235 ? -19.952 0.002   -53.335 1.00 35.86  ? 235 GLY D O   1 
ATOM   12175 N  N   . ALA D 1 236 ? -19.772 -1.792  -54.666 1.00 29.49  ? 236 ALA D N   1 
ATOM   12176 C  CA  . ALA D 1 236 ? -19.196 -2.610  -53.604 1.00 31.16  ? 236 ALA D CA  1 
ATOM   12177 C  C   . ALA D 1 236 ? -17.786 -2.164  -53.236 1.00 32.78  ? 236 ALA D C   1 
ATOM   12178 O  O   . ALA D 1 236 ? -17.376 -2.316  -52.081 1.00 32.56  ? 236 ALA D O   1 
ATOM   12179 C  CB  . ALA D 1 236 ? -19.174 -4.072  -54.035 1.00 34.33  ? 236 ALA D CB  1 
ATOM   12180 N  N   . ALA D 1 237 ? -17.015 -1.649  -54.201 1.00 31.01  ? 237 ALA D N   1 
ATOM   12181 C  CA  . ALA D 1 237 ? -15.676 -1.174  -53.868 1.00 26.01  ? 237 ALA D CA  1 
ATOM   12182 C  C   . ALA D 1 237 ? -15.749 0.081   -53.017 1.00 30.71  ? 237 ALA D C   1 
ATOM   12183 O  O   . ALA D 1 237 ? -14.905 0.275   -52.137 1.00 33.03  ? 237 ALA D O   1 
ATOM   12184 C  CB  . ALA D 1 237 ? -14.858 -0.934  -55.135 1.00 24.16  ? 237 ALA D CB  1 
ATOM   12185 N  N   . ALA D 1 238 ? -16.765 0.921   -53.243 1.00 32.52  ? 238 ALA D N   1 
ATOM   12186 C  CA  . ALA D 1 238 ? -17.008 2.072   -52.372 1.00 30.88  ? 238 ALA D CA  1 
ATOM   12187 C  C   . ALA D 1 238 ? -17.314 1.639   -50.940 1.00 34.86  ? 238 ALA D C   1 
ATOM   12188 O  O   . ALA D 1 238 ? -16.668 2.090   -49.980 1.00 36.08  ? 238 ALA D O   1 
ATOM   12189 C  CB  . ALA D 1 238 ? -18.161 2.906   -52.929 1.00 31.60  ? 238 ALA D CB  1 
ATOM   12190 N  N   . LEU D 1 239 ? -18.336 0.796   -50.780 1.00 30.96  ? 239 LEU D N   1 
ATOM   12191 C  CA  . LEU D 1 239 ? -18.690 0.274   -49.464 1.00 27.51  ? 239 LEU D CA  1 
ATOM   12192 C  C   . LEU D 1 239 ? -17.503 -0.414  -48.809 1.00 29.00  ? 239 LEU D C   1 
ATOM   12193 O  O   . LEU D 1 239 ? -17.219 -0.191  -47.627 1.00 31.29  ? 239 LEU D O   1 
ATOM   12194 C  CB  . LEU D 1 239 ? -19.866 -0.688  -49.591 1.00 29.17  ? 239 LEU D CB  1 
ATOM   12195 C  CG  . LEU D 1 239 ? -20.446 -1.209  -48.269 1.00 30.33  ? 239 LEU D CG  1 
ATOM   12196 C  CD1 . LEU D 1 239 ? -20.713 -0.044  -47.319 1.00 29.64  ? 239 LEU D CD1 1 
ATOM   12197 C  CD2 . LEU D 1 239 ? -21.704 -2.001  -48.530 1.00 32.97  ? 239 LEU D CD2 1 
ATOM   12198 N  N   . GLN D 1 240 ? -16.794 -1.260  -49.562 1.00 29.06  ? 240 GLN D N   1 
ATOM   12199 C  CA  . GLN D 1 240 ? -15.602 -1.899  -49.013 1.00 31.06  ? 240 GLN D CA  1 
ATOM   12200 C  C   . GLN D 1 240 ? -14.619 -0.859  -48.504 1.00 30.33  ? 240 GLN D C   1 
ATOM   12201 O  O   . GLN D 1 240 ? -14.032 -1.021  -47.428 1.00 32.46  ? 240 GLN D O   1 
ATOM   12202 C  CB  . GLN D 1 240 ? -14.936 -2.797  -50.058 1.00 31.47  ? 240 GLN D CB  1 
ATOM   12203 C  CG  . GLN D 1 240 ? -15.603 -4.153  -50.262 1.00 35.45  ? 240 GLN D CG  1 
ATOM   12204 C  CD  . GLN D 1 240 ? -15.100 -4.893  -51.505 1.00 33.60  ? 240 GLN D CD  1 
ATOM   12205 O  OE1 . GLN D 1 240 ? -14.019 -4.599  -52.043 1.00 42.50  ? 240 GLN D OE1 1 
ATOM   12206 N  NE2 . GLN D 1 240 ? -15.866 -5.874  -51.948 1.00 31.99  ? 240 GLN D NE2 1 
ATOM   12207 N  N   . ARG D 1 241 ? -14.468 0.241   -49.247 1.00 32.24  ? 241 ARG D N   1 
ATOM   12208 C  CA  . ARG D 1 241 ? -13.524 1.297   -48.893 1.00 27.95  ? 241 ARG D CA  1 
ATOM   12209 C  C   . ARG D 1 241 ? -13.965 2.031   -47.637 1.00 28.35  ? 241 ARG D C   1 
ATOM   12210 O  O   . ARG D 1 241 ? -13.143 2.340   -46.768 1.00 28.14  ? 241 ARG D O   1 
ATOM   12211 C  CB  . ARG D 1 241 ? -13.399 2.261   -50.082 1.00 32.27  ? 241 ARG D CB  1 
ATOM   12212 C  CG  . ARG D 1 241 ? -12.632 3.566   -49.868 1.00 30.13  ? 241 ARG D CG  1 
ATOM   12213 C  CD  . ARG D 1 241 ? -13.205 4.674   -50.790 1.00 30.02  ? 241 ARG D CD  1 
ATOM   12214 N  NE  . ARG D 1 241 ? -14.627 4.915   -50.525 1.00 39.32  ? 241 ARG D NE  1 
ATOM   12215 C  CZ  . ARG D 1 241 ? -15.554 5.166   -51.441 1.00 36.09  ? 241 ARG D CZ  1 
ATOM   12216 N  NH1 . ARG D 1 241 ? -15.282 5.125   -52.737 1.00 37.71  ? 241 ARG D NH1 1 
ATOM   12217 N  NH2 . ARG D 1 241 ? -16.792 5.455   -51.048 1.00 38.45  ? 241 ARG D NH2 1 
ATOM   12218 N  N   . ASP D 1 242 ? -15.259 2.306   -47.510 1.00 30.44  ? 242 ASP D N   1 
ATOM   12219 C  CA  . ASP D 1 242 ? -15.725 2.980   -46.306 1.00 30.52  ? 242 ASP D CA  1 
ATOM   12220 C  C   . ASP D 1 242 ? -15.765 2.038   -45.111 1.00 31.34  ? 242 ASP D C   1 
ATOM   12221 O  O   . ASP D 1 242 ? -15.607 2.490   -43.968 1.00 31.85  ? 242 ASP D O   1 
ATOM   12222 C  CB  . ASP D 1 242 ? -17.102 3.593   -46.544 1.00 33.11  ? 242 ASP D CB  1 
ATOM   12223 C  CG  . ASP D 1 242 ? -17.095 4.585   -47.678 1.00 33.59  ? 242 ASP D CG  1 
ATOM   12224 O  OD1 . ASP D 1 242 ? -16.175 5.426   -47.700 1.00 35.18  ? 242 ASP D OD1 1 
ATOM   12225 O  OD2 . ASP D 1 242 ? -18.004 4.520   -48.539 1.00 31.31  ? 242 ASP D OD2 1 
ATOM   12226 N  N   . LEU D 1 243 ? -15.990 0.743   -45.340 1.00 32.06  ? 243 LEU D N   1 
ATOM   12227 C  CA  . LEU D 1 243 ? -15.913 -0.213  -44.232 1.00 31.86  ? 243 LEU D CA  1 
ATOM   12228 C  C   . LEU D 1 243 ? -14.501 -0.252  -43.660 1.00 32.08  ? 243 LEU D C   1 
ATOM   12229 O  O   . LEU D 1 243 ? -14.315 -0.183  -42.439 1.00 32.38  ? 243 LEU D O   1 
ATOM   12230 C  CB  . LEU D 1 243 ? -16.347 -1.608  -44.695 1.00 36.49  ? 243 LEU D CB  1 
ATOM   12231 C  CG  . LEU D 1 243 ? -17.826 -1.963  -44.908 1.00 32.82  ? 243 LEU D CG  1 
ATOM   12232 C  CD1 . LEU D 1 243 ? -17.936 -3.202  -45.761 1.00 30.27  ? 243 LEU D CD1 1 
ATOM   12233 C  CD2 . LEU D 1 243 ? -18.516 -2.194  -43.580 1.00 31.12  ? 243 LEU D CD2 1 
ATOM   12234 N  N   . ARG D 1 244 ? -13.488 -0.297  -44.535 1.00 31.03  ? 244 ARG D N   1 
ATOM   12235 C  CA  . ARG D 1 244 ? -12.104 -0.231  -44.071 1.00 32.03  ? 244 ARG D CA  1 
ATOM   12236 C  C   . ARG D 1 244 ? -11.839 1.067   -43.318 1.00 34.07  ? 244 ARG D C   1 
ATOM   12237 O  O   . ARG D 1 244 ? -11.229 1.062   -42.245 1.00 31.61  ? 244 ARG D O   1 
ATOM   12238 C  CB  . ARG D 1 244 ? -11.153 -0.378  -45.253 1.00 32.46  ? 244 ARG D CB  1 
ATOM   12239 C  CG  . ARG D 1 244 ? -11.334 -1.704  -45.974 1.00 33.79  ? 244 ARG D CG  1 
ATOM   12240 C  CD  . ARG D 1 244 ? -10.162 -2.091  -46.822 1.00 34.50  ? 244 ARG D CD  1 
ATOM   12241 N  NE  . ARG D 1 244 ? -10.513 -3.196  -47.705 1.00 37.49  ? 244 ARG D NE  1 
ATOM   12242 C  CZ  . ARG D 1 244 ? -10.848 -3.049  -48.981 1.00 44.16  ? 244 ARG D CZ  1 
ATOM   12243 N  NH1 . ARG D 1 244 ? -10.843 -1.860  -49.563 1.00 44.59  ? 244 ARG D NH1 1 
ATOM   12244 N  NH2 . ARG D 1 244 ? -11.203 -4.119  -49.690 1.00 41.24  ? 244 ARG D NH2 1 
ATOM   12245 N  N   . LEU D 1 245 ? -12.286 2.197   -43.868 1.00 33.43  ? 245 LEU D N   1 
ATOM   12246 C  CA  . LEU D 1 245 ? -12.047 3.461   -43.181 1.00 33.33  ? 245 LEU D CA  1 
ATOM   12247 C  C   . LEU D 1 245 ? -12.732 3.465   -41.828 1.00 28.07  ? 245 LEU D C   1 
ATOM   12248 O  O   . LEU D 1 245 ? -12.135 3.869   -40.827 1.00 28.88  ? 245 LEU D O   1 
ATOM   12249 C  CB  . LEU D 1 245 ? -12.526 4.641   -44.032 1.00 29.47  ? 245 LEU D CB  1 
ATOM   12250 C  CG  . LEU D 1 245 ? -12.432 6.015   -43.363 1.00 29.40  ? 245 LEU D CG  1 
ATOM   12251 C  CD1 . LEU D 1 245 ? -10.978 6.369   -43.051 1.00 23.51  ? 245 LEU D CD1 1 
ATOM   12252 C  CD2 . LEU D 1 245 ? -13.060 7.062   -44.268 1.00 25.71  ? 245 LEU D CD2 1 
ATOM   12253 N  N   . ALA D 1 246 ? -13.985 2.997   -41.786 1.00 33.33  ? 246 ALA D N   1 
ATOM   12254 C  CA  . ALA D 1 246 ? -14.706 2.851   -40.526 1.00 27.04  ? 246 ALA D CA  1 
ATOM   12255 C  C   . ALA D 1 246 ? -13.925 2.018   -39.517 1.00 25.96  ? 246 ALA D C   1 
ATOM   12256 O  O   . ALA D 1 246 ? -13.797 2.402   -38.345 1.00 26.98  ? 246 ALA D O   1 
ATOM   12257 C  CB  . ALA D 1 246 ? -16.075 2.232   -40.783 1.00 26.18  ? 246 ALA D CB  1 
ATOM   12258 N  N   . LYS D 1 247 ? -13.390 0.879   -39.955 1.00 28.03  ? 247 LYS D N   1 
ATOM   12259 C  CA  . LYS D 1 247 ? -12.614 0.027   -39.056 1.00 29.00  ? 247 LYS D CA  1 
ATOM   12260 C  C   . LYS D 1 247 ? -11.348 0.732   -38.588 1.00 25.79  ? 247 LYS D C   1 
ATOM   12261 O  O   . LYS D 1 247 ? -11.042 0.757   -37.397 1.00 25.87  ? 247 LYS D O   1 
ATOM   12262 C  CB  . LYS D 1 247 ? -12.271 -1.296  -39.750 1.00 33.03  ? 247 LYS D CB  1 
ATOM   12263 C  CG  . LYS D 1 247 ? -11.381 -2.240  -38.932 1.00 30.31  ? 247 LYS D CG  1 
ATOM   12264 C  CD  . LYS D 1 247 ? -11.850 -2.342  -37.491 1.00 35.83  ? 247 LYS D CD  1 
ATOM   12265 C  CE  . LYS D 1 247 ? -11.536 -3.715  -36.877 1.00 35.20  ? 247 LYS D CE  1 
ATOM   12266 N  NZ  . LYS D 1 247 ? -10.228 -4.239  -37.342 1.00 38.97  ? 247 LYS D NZ  1 
ATOM   12267 N  N   . ARG D 1 248 ? -10.600 1.321   -39.517 1.00 28.97  ? 248 ARG D N   1 
ATOM   12268 C  CA  . ARG D 1 248 ? -9.390  2.055   -39.151 1.00 23.99  ? 248 ARG D CA  1 
ATOM   12269 C  C   . ARG D 1 248 ? -9.665  3.133   -38.109 1.00 27.66  ? 248 ARG D C   1 
ATOM   12270 O  O   . ARG D 1 248 ? -8.815  3.412   -37.253 1.00 32.43  ? 248 ARG D O   1 
ATOM   12271 C  CB  . ARG D 1 248 ? -8.781  2.679   -40.404 1.00 29.63  ? 248 ARG D CB  1 
ATOM   12272 C  CG  . ARG D 1 248 ? -7.556  3.524   -40.172 1.00 30.49  ? 248 ARG D CG  1 
ATOM   12273 C  CD  . ARG D 1 248 ? -7.067  3.984   -41.523 1.00 40.40  ? 248 ARG D CD  1 
ATOM   12274 N  NE  . ARG D 1 248 ? -5.904  4.851   -41.426 1.00 42.88  ? 248 ARG D NE  1 
ATOM   12275 C  CZ  . ARG D 1 248 ? -5.513  5.675   -42.388 1.00 37.06  ? 248 ARG D CZ  1 
ATOM   12276 N  NH1 . ARG D 1 248 ? -6.208  5.813   -43.513 1.00 31.57  ? 248 ARG D NH1 1 
ATOM   12277 N  NH2 . ARG D 1 248 ? -4.398  6.372   -42.222 1.00 37.68  ? 248 ARG D NH2 1 
ATOM   12278 N  N   . LEU D 1 249 ? -10.835 3.766   -38.168 1.00 24.51  ? 249 LEU D N   1 
ATOM   12279 C  CA  . LEU D 1 249 ? -11.127 4.836   -37.226 1.00 25.70  ? 249 LEU D CA  1 
ATOM   12280 C  C   . LEU D 1 249 ? -11.868 4.355   -35.978 1.00 27.23  ? 249 LEU D C   1 
ATOM   12281 O  O   . LEU D 1 249 ? -12.247 5.191   -35.148 1.00 24.15  ? 249 LEU D O   1 
ATOM   12282 C  CB  . LEU D 1 249 ? -11.933 5.942   -37.924 1.00 27.89  ? 249 LEU D CB  1 
ATOM   12283 C  CG  . LEU D 1 249 ? -11.233 6.661   -39.102 1.00 21.96  ? 249 LEU D CG  1 
ATOM   12284 C  CD1 . LEU D 1 249 ? -12.024 7.874   -39.531 1.00 25.00  ? 249 LEU D CD1 1 
ATOM   12285 C  CD2 . LEU D 1 249 ? -9.827  7.041   -38.781 1.00 22.60  ? 249 LEU D CD2 1 
ATOM   12286 N  N   . GLY D 1 250 ? -12.125 3.047   -35.847 1.00 27.39  ? 250 GLY D N   1 
ATOM   12287 C  CA  . GLY D 1 250 ? -12.705 2.466   -34.632 1.00 26.27  ? 250 GLY D CA  1 
ATOM   12288 C  C   . GLY D 1 250 ? -14.218 2.288   -34.608 1.00 30.98  ? 250 GLY D C   1 
ATOM   12289 O  O   . GLY D 1 250 ? -14.750 1.772   -33.610 1.00 30.54  ? 250 GLY D O   1 
ATOM   12290 N  N   . PHE D 1 251 ? -14.930 2.702   -35.652 1.00 29.61  ? 251 PHE D N   1 
ATOM   12291 C  CA  . PHE D 1 251 ? -16.382 2.560   -35.701 1.00 30.10  ? 251 PHE D CA  1 
ATOM   12292 C  C   . PHE D 1 251 ? -16.775 1.083   -35.764 1.00 35.34  ? 251 PHE D C   1 
ATOM   12293 O  O   . PHE D 1 251 ? -16.046 0.254   -36.308 1.00 36.25  ? 251 PHE D O   1 
ATOM   12294 C  CB  . PHE D 1 251 ? -16.948 3.321   -36.917 1.00 31.79  ? 251 PHE D CB  1 
ATOM   12295 C  CG  . PHE D 1 251 ? -16.836 4.819   -36.786 1.00 30.48  ? 251 PHE D CG  1 
ATOM   12296 C  CD1 . PHE D 1 251 ? -15.686 5.491   -37.215 1.00 31.02  ? 251 PHE D CD1 1 
ATOM   12297 C  CD2 . PHE D 1 251 ? -17.841 5.546   -36.161 1.00 27.13  ? 251 PHE D CD2 1 
ATOM   12298 C  CE1 . PHE D 1 251 ? -15.559 6.874   -37.049 1.00 24.44  ? 251 PHE D CE1 1 
ATOM   12299 C  CE2 . PHE D 1 251 ? -17.729 6.918   -35.995 1.00 27.56  ? 251 PHE D CE2 1 
ATOM   12300 C  CZ  . PHE D 1 251 ? -16.583 7.586   -36.440 1.00 26.50  ? 251 PHE D CZ  1 
ATOM   12301 N  N   . ARG D 1 252 ? -17.938 0.748   -35.186 1.00 30.88  ? 252 ARG D N   1 
ATOM   12302 C  CA  . ARG D 1 252 ? -18.484 -0.601  -35.297 1.00 37.54  ? 252 ARG D CA  1 
ATOM   12303 C  C   . ARG D 1 252 ? -19.690 -0.674  -36.220 1.00 40.33  ? 252 ARG D C   1 
ATOM   12304 O  O   . ARG D 1 252 ? -20.224 -1.770  -36.442 1.00 34.48  ? 252 ARG D O   1 
ATOM   12305 C  CB  . ARG D 1 252 ? -18.857 -1.185  -33.923 1.00 39.33  ? 252 ARG D CB  1 
ATOM   12306 C  CG  . ARG D 1 252 ? -18.977 -0.205  -32.779 1.00 41.61  ? 252 ARG D CG  1 
ATOM   12307 C  CD  . ARG D 1 252 ? -19.222 -0.927  -31.442 1.00 41.12  ? 252 ARG D CD  1 
ATOM   12308 N  NE  . ARG D 1 252 ? -20.574 -0.703  -30.929 1.00 47.92  ? 252 ARG D NE  1 
ATOM   12309 C  CZ  . ARG D 1 252 ? -20.869 0.075   -29.891 1.00 48.07  ? 252 ARG D CZ  1 
ATOM   12310 N  NH1 . ARG D 1 252 ? -19.925 0.703   -29.205 1.00 46.47  ? 252 ARG D NH1 1 
ATOM   12311 N  NH2 . ARG D 1 252 ? -22.142 0.233   -29.536 1.00 47.27  ? 252 ARG D NH2 1 
ATOM   12312 N  N   . PHE D 1 253 ? -20.106 0.453   -36.792 1.00 37.79  ? 253 PHE D N   1 
ATOM   12313 C  CA  . PHE D 1 253 ? -21.229 0.500   -37.713 1.00 38.42  ? 253 PHE D CA  1 
ATOM   12314 C  C   . PHE D 1 253 ? -20.857 1.318   -38.946 1.00 32.04  ? 253 PHE D C   1 
ATOM   12315 O  O   . PHE D 1 253 ? -20.040 2.232   -38.871 1.00 38.25  ? 253 PHE D O   1 
ATOM   12316 C  CB  . PHE D 1 253 ? -22.457 1.115   -37.037 1.00 39.13  ? 253 PHE D CB  1 
ATOM   12317 C  CG  . PHE D 1 253 ? -22.953 0.337   -35.854 1.00 38.70  ? 253 PHE D CG  1 
ATOM   12318 C  CD1 . PHE D 1 253 ? -23.185 -1.028  -35.951 1.00 37.33  ? 253 PHE D CD1 1 
ATOM   12319 C  CD2 . PHE D 1 253 ? -23.197 0.971   -34.649 1.00 36.59  ? 253 PHE D CD2 1 
ATOM   12320 C  CE1 . PHE D 1 253 ? -23.650 -1.744  -34.865 1.00 36.93  ? 253 PHE D CE1 1 
ATOM   12321 C  CE2 . PHE D 1 253 ? -23.665 0.258   -33.556 1.00 37.97  ? 253 PHE D CE2 1 
ATOM   12322 C  CZ  . PHE D 1 253 ? -23.888 -1.095  -33.659 1.00 34.56  ? 253 PHE D CZ  1 
ATOM   12323 N  N   . VAL D 1 254 ? -21.444 0.961   -40.084 1.00 33.18  ? 254 VAL D N   1 
ATOM   12324 C  CA  . VAL D 1 254 ? -21.440 1.781   -41.293 1.00 34.94  ? 254 VAL D CA  1 
ATOM   12325 C  C   . VAL D 1 254 ? -22.860 1.833   -41.844 1.00 34.32  ? 254 VAL D C   1 
ATOM   12326 O  O   . VAL D 1 254 ? -23.475 0.787   -42.064 1.00 36.28  ? 254 VAL D O   1 
ATOM   12327 C  CB  . VAL D 1 254 ? -20.486 1.245   -42.377 1.00 30.92  ? 254 VAL D CB  1 
ATOM   12328 C  CG1 . VAL D 1 254 ? -20.478 2.199   -43.583 1.00 33.05  ? 254 VAL D CG1 1 
ATOM   12329 C  CG2 . VAL D 1 254 ? -19.108 1.087   -41.835 1.00 35.95  ? 254 VAL D CG2 1 
ATOM   12330 N  N   . ARG D 1 255 ? -23.366 3.049   -42.087 1.00 33.55  ? 255 ARG D N   1 
ATOM   12331 C  CA  . ARG D 1 255 ? -24.658 3.329   -42.691 1.00 30.27  ? 255 ARG D CA  1 
ATOM   12332 C  C   . ARG D 1 255 ? -24.492 3.708   -44.156 1.00 39.14  ? 255 ARG D C   1 
ATOM   12333 O  O   . ARG D 1 255 ? -24.373 4.898   -44.465 1.00 38.41  ? 255 ARG D O   1 
ATOM   12334 C  CB  . ARG D 1 255 ? -25.353 4.481   -41.961 1.00 34.19  ? 255 ARG D CB  1 
ATOM   12335 C  CG  . ARG D 1 255 ? -26.826 4.628   -42.271 1.00 34.27  ? 255 ARG D CG  1 
ATOM   12336 C  CD  . ARG D 1 255 ? -27.208 5.724   -43.254 1.00 41.51  ? 255 ARG D CD  1 
ATOM   12337 N  NE  . ARG D 1 255 ? -26.120 6.542   -43.786 1.00 43.18  ? 255 ARG D NE  1 
ATOM   12338 C  CZ  . ARG D 1 255 ? -26.154 7.868   -43.873 1.00 40.26  ? 255 ARG D CZ  1 
ATOM   12339 N  NH1 . ARG D 1 255 ? -27.167 8.568   -43.381 1.00 35.43  ? 255 ARG D NH1 1 
ATOM   12340 N  NH2 . ARG D 1 255 ? -25.155 8.507   -44.487 1.00 36.27  ? 255 ARG D NH2 1 
ATOM   12341 N  N   . PRO D 1 256 ? -24.486 2.769   -45.080 1.00 36.43  ? 256 PRO D N   1 
ATOM   12342 C  CA  . PRO D 1 256 ? -24.447 3.154   -46.494 1.00 36.91  ? 256 PRO D CA  1 
ATOM   12343 C  C   . PRO D 1 256 ? -25.781 3.694   -46.983 1.00 39.37  ? 256 PRO D C   1 
ATOM   12344 O  O   . PRO D 1 256 ? -26.779 2.966   -47.064 1.00 38.38  ? 256 PRO D O   1 
ATOM   12345 C  CB  . PRO D 1 256 ? -24.062 1.849   -47.201 1.00 32.27  ? 256 PRO D CB  1 
ATOM   12346 C  CG  . PRO D 1 256 ? -24.561 0.805   -46.320 1.00 32.70  ? 256 PRO D CG  1 
ATOM   12347 C  CD  . PRO D 1 256 ? -24.449 1.312   -44.913 1.00 37.87  ? 256 PRO D CD  1 
ATOM   12348 N  N   . LYS D 1 257 ? -25.798 4.988   -47.298 1.00 38.32  ? 257 LYS D N   1 
ATOM   12349 C  CA  . LYS D 1 257 ? -26.945 5.626   -47.931 1.00 41.06  ? 257 LYS D CA  1 
ATOM   12350 C  C   . LYS D 1 257 ? -26.840 5.398   -49.442 1.00 40.65  ? 257 LYS D C   1 
ATOM   12351 O  O   . LYS D 1 257 ? -25.960 5.961   -50.098 1.00 39.20  ? 257 LYS D O   1 
ATOM   12352 C  CB  . LYS D 1 257 ? -26.971 7.113   -47.579 1.00 37.42  ? 257 LYS D CB  1 
ATOM   12353 C  CG  . LYS D 1 257 ? -28.354 7.774   -47.658 1.00 41.82  ? 257 LYS D CG  1 
ATOM   12354 C  CD  . LYS D 1 257 ? -29.021 7.773   -46.291 1.00 45.11  ? 257 LYS D CD  1 
ATOM   12355 C  CE  . LYS D 1 257 ? -30.289 8.610   -46.284 1.00 46.39  ? 257 LYS D CE  1 
ATOM   12356 N  NZ  . LYS D 1 257 ? -30.139 9.832   -47.140 1.00 50.66  ? 257 LYS D NZ  1 
ATOM   12357 N  N   . ILE D 1 258 ? -27.734 4.560   -49.999 1.00 38.56  ? 258 ILE D N   1 
ATOM   12358 C  CA  . ILE D 1 258 ? -27.718 4.172   -51.406 1.00 43.25  ? 258 ILE D CA  1 
ATOM   12359 C  C   . ILE D 1 258 ? -28.626 5.098   -52.216 1.00 40.63  ? 258 ILE D C   1 
ATOM   12360 O  O   . ILE D 1 258 ? -29.645 5.594   -51.729 1.00 39.91  ? 258 ILE D O   1 
ATOM   12361 C  CB  . ILE D 1 258 ? -28.139 2.689   -51.520 1.00 46.53  ? 258 ILE D CB  1 
ATOM   12362 C  CG1 . ILE D 1 258 ? -28.343 2.245   -52.966 1.00 46.37  ? 258 ILE D CG1 1 
ATOM   12363 C  CG2 . ILE D 1 258 ? -29.375 2.414   -50.679 1.00 49.11  ? 258 ILE D CG2 1 
ATOM   12364 C  CD1 . ILE D 1 258 ? -27.082 1.917   -53.689 1.00 44.46  ? 258 ILE D CD1 1 
ATOM   12365 N  N   . GLY D 1 259 ? -28.248 5.357   -53.463 1.00 43.30  ? 259 GLY D N   1 
ATOM   12366 C  CA  . GLY D 1 259 ? -29.131 6.090   -54.351 1.00 46.63  ? 259 GLY D CA  1 
ATOM   12367 C  C   . GLY D 1 259 ? -30.469 5.393   -54.522 1.00 47.89  ? 259 GLY D C   1 
ATOM   12368 O  O   . GLY D 1 259 ? -30.610 4.192   -54.286 1.00 49.16  ? 259 GLY D O   1 
ATOM   12369 N  N   . VAL D 1 260 ? -31.473 6.169   -54.934 1.00 48.51  ? 260 VAL D N   1 
ATOM   12370 C  CA  . VAL D 1 260 ? -32.854 5.700   -55.031 1.00 54.66  ? 260 VAL D CA  1 
ATOM   12371 C  C   . VAL D 1 260 ? -33.329 5.787   -56.481 1.00 53.49  ? 260 VAL D C   1 
ATOM   12372 O  O   . VAL D 1 260 ? -32.711 6.438   -57.323 1.00 54.41  ? 260 VAL D O   1 
ATOM   12373 C  CB  . VAL D 1 260 ? -33.800 6.499   -54.118 1.00 51.43  ? 260 VAL D CB  1 
ATOM   12374 C  CG1 . VAL D 1 260 ? -33.206 6.632   -52.726 1.00 54.88  ? 260 VAL D CG1 1 
ATOM   12375 C  CG2 . VAL D 1 260 ? -34.070 7.859   -54.727 1.00 50.01  ? 260 VAL D CG2 1 
ATOM   12376 N  N   . VAL D 1 261 ? -34.467 5.135   -56.757 1.00 59.24  ? 261 VAL D N   1 
ATOM   12377 C  CA  . VAL D 1 261 ? -35.082 5.166   -58.087 1.00 60.15  ? 261 VAL D CA  1 
ATOM   12378 C  C   . VAL D 1 261 ? -36.597 5.380   -58.009 1.00 63.63  ? 261 VAL D C   1 
ATOM   12379 O  O   . VAL D 1 261 ? -37.280 5.419   -59.041 1.00 59.90  ? 261 VAL D O   1 
ATOM   12380 C  CB  . VAL D 1 261 ? -34.758 3.882   -58.877 1.00 58.14  ? 261 VAL D CB  1 
ATOM   12381 C  CG1 . VAL D 1 261 ? -33.312 3.893   -59.352 1.00 47.95  ? 261 VAL D CG1 1 
ATOM   12382 C  CG2 . VAL D 1 261 ? -35.044 2.647   -58.039 1.00 57.60  ? 261 VAL D CG2 1 
ATOM   12383 N  N   . SER D 1 262 ? -37.133 5.538   -56.795 1.00 65.60  ? 262 SER D N   1 
ATOM   12384 C  CA  . SER D 1 262 ? -38.560 5.762   -56.584 1.00 70.28  ? 262 SER D CA  1 
ATOM   12385 C  C   . SER D 1 262 ? -38.764 6.875   -55.561 1.00 66.17  ? 262 SER D C   1 
ATOM   12386 O  O   . SER D 1 262 ? -37.880 7.178   -54.755 1.00 63.93  ? 262 SER D O   1 
ATOM   12387 C  CB  . SER D 1 262 ? -39.269 4.482   -56.107 1.00 69.10  ? 262 SER D CB  1 
ATOM   12388 O  OG  . SER D 1 262 ? -39.479 4.509   -54.704 1.00 66.74  ? 262 SER D OG  1 
ATOM   12389 N  N   . SER D 1 263 ? -39.965 7.467   -55.582 1.00 64.21  ? 263 SER D N   1 
ATOM   12390 C  CA  . SER D 1 263 ? -40.252 8.579   -54.678 1.00 68.54  ? 263 SER D CA  1 
ATOM   12391 C  C   . SER D 1 263 ? -40.328 8.145   -53.217 1.00 67.41  ? 263 SER D C   1 
ATOM   12392 O  O   . SER D 1 263 ? -40.227 8.996   -52.327 1.00 66.95  ? 263 SER D O   1 
ATOM   12393 C  CB  . SER D 1 263 ? -41.552 9.282   -55.091 1.00 70.15  ? 263 SER D CB  1 
ATOM   12394 O  OG  . SER D 1 263 ? -42.702 8.606   -54.611 1.00 72.49  ? 263 SER D OG  1 
ATOM   12395 N  N   . ASP D 1 264 ? -40.504 6.849   -52.949 1.00 73.00  ? 264 ASP D N   1 
ATOM   12396 C  CA  . ASP D 1 264 ? -40.470 6.314   -51.592 1.00 73.02  ? 264 ASP D CA  1 
ATOM   12397 C  C   . ASP D 1 264 ? -39.142 5.622   -51.282 1.00 71.68  ? 264 ASP D C   1 
ATOM   12398 O  O   . ASP D 1 264 ? -39.117 4.611   -50.567 1.00 70.28  ? 264 ASP D O   1 
ATOM   12399 C  CB  . ASP D 1 264 ? -41.650 5.368   -51.356 1.00 69.72  ? 264 ASP D CB  1 
ATOM   12400 C  CG  . ASP D 1 264 ? -41.669 4.196   -52.324 1.00 71.99  ? 264 ASP D CG  1 
ATOM   12401 O  OD1 . ASP D 1 264 ? -41.500 4.423   -53.544 1.00 65.42  ? 264 ASP D OD1 1 
ATOM   12402 O  OD2 . ASP D 1 264 ? -41.863 3.048   -51.859 1.00 63.99  ? 264 ASP D OD2 1 
ATOM   12403 N  N   . LEU D 1 265 ? -38.042 6.142   -51.843 1.00 67.14  ? 265 LEU D N   1 
ATOM   12404 C  CA  . LEU D 1 265 ? -36.671 5.831   -51.419 1.00 65.67  ? 265 LEU D CA  1 
ATOM   12405 C  C   . LEU D 1 265 ? -36.317 4.352   -51.597 1.00 65.94  ? 265 LEU D C   1 
ATOM   12406 O  O   . LEU D 1 265 ? -35.586 3.769   -50.790 1.00 61.02  ? 265 LEU D O   1 
ATOM   12407 C  CB  . LEU D 1 265 ? -36.423 6.282   -49.972 1.00 65.15  ? 265 LEU D CB  1 
ATOM   12408 C  CG  . LEU D 1 265 ? -36.723 7.746   -49.593 1.00 63.16  ? 265 LEU D CG  1 
ATOM   12409 C  CD1 . LEU D 1 265 ? -36.052 8.126   -48.271 1.00 63.03  ? 265 LEU D CD1 1 
ATOM   12410 C  CD2 . LEU D 1 265 ? -36.327 8.725   -50.701 1.00 59.41  ? 265 LEU D CD2 1 
ATOM   12411 N  N   . ILE D 1 266 ? -36.808 3.750   -52.675 1.00 61.83  ? 266 ILE D N   1 
ATOM   12412 C  CA  . ILE D 1 266 ? -36.458 2.354   -52.973 1.00 65.23  ? 266 ILE D CA  1 
ATOM   12413 C  C   . ILE D 1 266 ? -35.029 2.303   -53.509 1.00 58.95  ? 266 ILE D C   1 
ATOM   12414 O  O   . ILE D 1 266 ? -34.702 3.038   -54.456 1.00 56.76  ? 266 ILE D O   1 
ATOM   12415 C  CB  . ILE D 1 266 ? -37.452 1.751   -53.975 1.00 61.03  ? 266 ILE D CB  1 
ATOM   12416 C  CG1 . ILE D 1 266 ? -38.775 1.406   -53.273 1.00 68.30  ? 266 ILE D CG1 1 
ATOM   12417 C  CG2 . ILE D 1 266 ? -36.852 0.521   -54.655 1.00 62.35  ? 266 ILE D CG2 1 
ATOM   12418 C  CD1 . ILE D 1 266 ? -39.644 0.380   -54.005 1.00 62.07  ? 266 ILE D CD1 1 
ATOM   12419 N  N   . PRO D 1 267 ? -34.154 1.469   -52.946 1.00 62.20  ? 267 PRO D N   1 
ATOM   12420 C  CA  . PRO D 1 267 ? -32.742 1.490   -53.350 1.00 58.10  ? 267 PRO D CA  1 
ATOM   12421 C  C   . PRO D 1 267 ? -32.538 0.997   -54.775 1.00 57.29  ? 267 PRO D C   1 
ATOM   12422 O  O   . PRO D 1 267 ? -33.272 0.139   -55.274 1.00 59.75  ? 267 PRO D O   1 
ATOM   12423 C  CB  . PRO D 1 267 ? -32.069 0.547   -52.342 1.00 55.95  ? 267 PRO D CB  1 
ATOM   12424 C  CG  . PRO D 1 267 ? -33.020 0.475   -51.175 1.00 58.75  ? 267 PRO D CG  1 
ATOM   12425 C  CD  . PRO D 1 267 ? -34.385 0.576   -51.795 1.00 60.78  ? 267 PRO D CD  1 
ATOM   12426 N  N   . HIS D 1 268 ? -31.521 1.564   -55.425 1.00 49.28  ? 268 HIS D N   1 
ATOM   12427 C  CA  . HIS D 1 268 ? -31.116 1.126   -56.752 1.00 45.45  ? 268 HIS D CA  1 
ATOM   12428 C  C   . HIS D 1 268 ? -30.925 -0.392  -56.769 1.00 46.72  ? 268 HIS D C   1 
ATOM   12429 O  O   . HIS D 1 268 ? -30.485 -0.971  -55.766 1.00 49.03  ? 268 HIS D O   1 
ATOM   12430 C  CB  . HIS D 1 268 ? -29.823 1.848   -57.155 1.00 42.70  ? 268 HIS D CB  1 
ATOM   12431 C  CG  . HIS D 1 268 ? -29.431 1.648   -58.586 1.00 41.28  ? 268 HIS D CG  1 
ATOM   12432 N  ND1 . HIS D 1 268 ? -28.750 0.533   -59.022 1.00 40.75  ? 268 HIS D ND1 1 
ATOM   12433 C  CD2 . HIS D 1 268 ? -29.630 2.418   -59.684 1.00 43.78  ? 268 HIS D CD2 1 
ATOM   12434 C  CE1 . HIS D 1 268 ? -28.542 0.624   -60.324 1.00 43.42  ? 268 HIS D CE1 1 
ATOM   12435 N  NE2 . HIS D 1 268 ? -29.071 1.757   -60.752 1.00 41.14  ? 268 HIS D NE2 1 
ATOM   12436 N  N   . PRO D 1 269 ? -31.248 -1.067  -57.877 1.00 43.99  ? 269 PRO D N   1 
ATOM   12437 C  CA  . PRO D 1 269 ? -31.190 -2.538  -57.895 1.00 44.39  ? 269 PRO D CA  1 
ATOM   12438 C  C   . PRO D 1 269 ? -29.837 -3.123  -57.541 1.00 46.63  ? 269 PRO D C   1 
ATOM   12439 O  O   . PRO D 1 269 ? -29.773 -4.289  -57.121 1.00 47.19  ? 269 PRO D O   1 
ATOM   12440 C  CB  . PRO D 1 269 ? -31.576 -2.885  -59.339 1.00 46.53  ? 269 PRO D CB  1 
ATOM   12441 C  CG  . PRO D 1 269 ? -32.382 -1.723  -59.798 1.00 45.99  ? 269 PRO D CG  1 
ATOM   12442 C  CD  . PRO D 1 269 ? -31.800 -0.520  -59.128 1.00 44.99  ? 269 PRO D CD  1 
ATOM   12443 N  N   . ILE D 1 270 ? -28.748 -2.371  -57.700 1.00 42.51  ? 270 ILE D N   1 
ATOM   12444 C  CA  . ILE D 1 270 ? -27.447 -2.929  -57.356 1.00 42.03  ? 270 ILE D CA  1 
ATOM   12445 C  C   . ILE D 1 270 ? -27.313 -3.159  -55.860 1.00 37.85  ? 270 ILE D C   1 
ATOM   12446 O  O   . ILE D 1 270 ? -26.433 -3.907  -55.435 1.00 39.01  ? 270 ILE D O   1 
ATOM   12447 C  CB  . ILE D 1 270 ? -26.303 -2.018  -57.847 1.00 39.05  ? 270 ILE D CB  1 
ATOM   12448 C  CG1 . ILE D 1 270 ? -26.429 -0.622  -57.241 1.00 39.38  ? 270 ILE D CG1 1 
ATOM   12449 C  CG2 . ILE D 1 270 ? -26.301 -1.936  -59.355 1.00 40.61  ? 270 ILE D CG2 1 
ATOM   12450 C  CD1 . ILE D 1 270 ? -25.111 0.130   -57.165 1.00 36.13  ? 270 ILE D CD1 1 
ATOM   12451 N  N   . TRP D 1 271 ? -28.163 -2.536  -55.044 1.00 41.30  ? 271 TRP D N   1 
ATOM   12452 C  CA  . TRP D 1 271 ? -27.900 -2.505  -53.612 1.00 46.11  ? 271 TRP D CA  1 
ATOM   12453 C  C   . TRP D 1 271 ? -27.734 -3.899  -53.031 1.00 46.28  ? 271 TRP D C   1 
ATOM   12454 O  O   . TRP D 1 271 ? -27.029 -4.054  -52.031 1.00 46.22  ? 271 TRP D O   1 
ATOM   12455 C  CB  . TRP D 1 271 ? -29.000 -1.727  -52.877 1.00 47.05  ? 271 TRP D CB  1 
ATOM   12456 C  CG  . TRP D 1 271 ? -30.096 -2.572  -52.300 1.00 53.59  ? 271 TRP D CG  1 
ATOM   12457 C  CD1 . TRP D 1 271 ? -31.329 -2.778  -52.843 1.00 56.80  ? 271 TRP D CD1 1 
ATOM   12458 C  CD2 . TRP D 1 271 ? -30.077 -3.306  -51.060 1.00 52.07  ? 271 TRP D CD2 1 
ATOM   12459 N  NE1 . TRP D 1 271 ? -32.073 -3.604  -52.032 1.00 63.98  ? 271 TRP D NE1 1 
ATOM   12460 C  CE2 . TRP D 1 271 ? -31.327 -3.942  -50.932 1.00 60.11  ? 271 TRP D CE2 1 
ATOM   12461 C  CE3 . TRP D 1 271 ? -29.124 -3.495  -50.058 1.00 52.75  ? 271 TRP D CE3 1 
ATOM   12462 C  CZ2 . TRP D 1 271 ? -31.649 -4.751  -49.839 1.00 57.42  ? 271 TRP D CZ2 1 
ATOM   12463 C  CZ3 . TRP D 1 271 ? -29.444 -4.295  -48.979 1.00 56.17  ? 271 TRP D CZ3 1 
ATOM   12464 C  CH2 . TRP D 1 271 ? -30.694 -4.916  -48.879 1.00 51.32  ? 271 TRP D CH2 1 
ATOM   12465 N  N   . THR D 1 272 ? -28.290 -4.925  -53.672 1.00 48.21  ? 272 THR D N   1 
ATOM   12466 C  CA  . THR D 1 272 ? -28.293 -6.234  -53.032 1.00 49.20  ? 272 THR D CA  1 
ATOM   12467 C  C   . THR D 1 272 ? -26.993 -7.009  -53.256 1.00 44.88  ? 272 THR D C   1 
ATOM   12468 O  O   . THR D 1 272 ? -26.437 -7.552  -52.299 1.00 46.57  ? 272 THR D O   1 
ATOM   12469 C  CB  . THR D 1 272 ? -29.517 -7.033  -53.489 1.00 46.94  ? 272 THR D CB  1 
ATOM   12470 O  OG1 . THR D 1 272 ? -30.686 -6.470  -52.877 1.00 43.94  ? 272 THR D OG1 1 
ATOM   12471 C  CG2 . THR D 1 272 ? -29.384 -8.483  -53.095 1.00 43.64  ? 272 THR D CG2 1 
ATOM   12472 N  N   . GLU D 1 273 ? -26.472 -7.068  -54.483 1.00 42.48  ? 273 GLU D N   1 
ATOM   12473 C  CA  . GLU D 1 273 ? -25.175 -7.727  -54.640 1.00 46.05  ? 273 GLU D CA  1 
ATOM   12474 C  C   . GLU D 1 273 ? -24.055 -6.869  -54.074 1.00 43.84  ? 273 GLU D C   1 
ATOM   12475 O  O   . GLU D 1 273 ? -23.021 -7.398  -53.649 1.00 49.65  ? 273 GLU D O   1 
ATOM   12476 C  CB  . GLU D 1 273 ? -24.872 -8.066  -56.105 1.00 41.59  ? 273 GLU D CB  1 
ATOM   12477 C  CG  . GLU D 1 273 ? -26.072 -8.330  -56.981 1.00 46.18  ? 273 GLU D CG  1 
ATOM   12478 C  CD  . GLU D 1 273 ? -25.681 -8.807  -58.376 1.00 52.23  ? 273 GLU D CD  1 
ATOM   12479 O  OE1 . GLU D 1 273 ? -24.468 -8.862  -58.678 1.00 56.21  ? 273 GLU D OE1 1 
ATOM   12480 O  OE2 . GLU D 1 273 ? -26.587 -9.107  -59.183 1.00 59.47  ? 273 GLU D OE2 1 
ATOM   12481 N  N   . VAL D 1 274 ? -24.242 -5.551  -54.046 1.00 41.74  ? 274 VAL D N   1 
ATOM   12482 C  CA  . VAL D 1 274 ? -23.225 -4.678  -53.470 1.00 41.10  ? 274 VAL D CA  1 
ATOM   12483 C  C   . VAL D 1 274 ? -23.006 -5.034  -52.003 1.00 43.51  ? 274 VAL D C   1 
ATOM   12484 O  O   . VAL D 1 274 ? -21.864 -5.147  -51.533 1.00 35.49  ? 274 VAL D O   1 
ATOM   12485 C  CB  . VAL D 1 274 ? -23.637 -3.204  -53.647 1.00 37.45  ? 274 VAL D CB  1 
ATOM   12486 C  CG1 . VAL D 1 274 ? -22.850 -2.319  -52.718 1.00 38.00  ? 274 VAL D CG1 1 
ATOM   12487 C  CG2 . VAL D 1 274 ? -23.460 -2.770  -55.104 1.00 38.35  ? 274 VAL D CG2 1 
ATOM   12488 N  N   . VAL D 1 275 ? -24.101 -5.241  -51.265 1.00 45.39  ? 275 VAL D N   1 
ATOM   12489 C  CA  . VAL D 1 275 ? -24.008 -5.610  -49.854 1.00 42.71  ? 275 VAL D CA  1 
ATOM   12490 C  C   . VAL D 1 275 ? -23.478 -7.033  -49.711 1.00 41.35  ? 275 VAL D C   1 
ATOM   12491 O  O   . VAL D 1 275 ? -22.576 -7.294  -48.907 1.00 41.67  ? 275 VAL D O   1 
ATOM   12492 C  CB  . VAL D 1 275 ? -25.377 -5.436  -49.171 1.00 42.04  ? 275 VAL D CB  1 
ATOM   12493 C  CG1 . VAL D 1 275 ? -25.394 -6.105  -47.801 1.00 45.01  ? 275 VAL D CG1 1 
ATOM   12494 C  CG2 . VAL D 1 275 ? -25.716 -3.983  -49.049 1.00 38.89  ? 275 VAL D CG2 1 
ATOM   12495 N  N   . GLU D 1 276 ? -24.028 -7.972  -50.492 1.00 41.63  ? 276 GLU D N   1 
ATOM   12496 C  CA  . GLU D 1 276 ? -23.541 -9.346  -50.458 1.00 38.20  ? 276 GLU D CA  1 
ATOM   12497 C  C   . GLU D 1 276 ? -22.070 -9.418  -50.820 1.00 38.17  ? 276 GLU D C   1 
ATOM   12498 O  O   . GLU D 1 276 ? -21.323 -10.215 -50.244 1.00 40.02  ? 276 GLU D O   1 
ATOM   12499 C  CB  . GLU D 1 276 ? -24.349 -10.226 -51.408 1.00 50.04  ? 276 GLU D CB  1 
ATOM   12500 C  CG  . GLU D 1 276 ? -25.832 -10.275 -51.103 1.00 54.14  ? 276 GLU D CG  1 
ATOM   12501 C  CD  . GLU D 1 276 ? -26.320 -11.671 -50.773 1.00 55.74  ? 276 GLU D CD  1 
ATOM   12502 O  OE1 . GLU D 1 276 ? -25.647 -12.369 -49.983 1.00 58.12  ? 276 GLU D OE1 1 
ATOM   12503 O  OE2 . GLU D 1 276 ? -27.368 -12.074 -51.319 1.00 58.37  ? 276 GLU D OE2 1 
ATOM   12504 N  N   . ALA D 1 277 ? -21.630 -8.606  -51.784 1.00 39.32  ? 277 ALA D N   1 
ATOM   12505 C  CA  . ALA D 1 277 ? -20.206 -8.547  -52.074 1.00 30.59  ? 277 ALA D CA  1 
ATOM   12506 C  C   . ALA D 1 277 ? -19.417 -8.063  -50.877 1.00 34.70  ? 277 ALA D C   1 
ATOM   12507 O  O   . ALA D 1 277 ? -18.229 -8.374  -50.772 1.00 35.98  ? 277 ALA D O   1 
ATOM   12508 C  CB  . ALA D 1 277 ? -19.942 -7.630  -53.263 1.00 35.28  ? 277 ALA D CB  1 
ATOM   12509 N  N   . SER D 1 278 ? -20.062 -7.323  -49.967 1.00 35.68  ? 278 SER D N   1 
ATOM   12510 C  CA  . SER D 1 278 ? -19.390 -6.642  -48.869 1.00 36.91  ? 278 SER D CA  1 
ATOM   12511 C  C   . SER D 1 278 ? -19.495 -7.363  -47.532 1.00 38.85  ? 278 SER D C   1 
ATOM   12512 O  O   . SER D 1 278 ? -18.715 -7.052  -46.625 1.00 35.90  ? 278 SER D O   1 
ATOM   12513 C  CB  . SER D 1 278 ? -19.949 -5.226  -48.714 1.00 38.74  ? 278 SER D CB  1 
ATOM   12514 O  OG  . SER D 1 278 ? -19.644 -4.435  -49.850 1.00 38.99  ? 278 SER D OG  1 
ATOM   12515 N  N   . LEU D 1 279 ? -20.417 -8.317  -47.390 1.00 38.32  ? 279 LEU D N   1 
ATOM   12516 C  CA  . LEU D 1 279 ? -20.560 -9.018  -46.115 1.00 37.26  ? 279 LEU D CA  1 
ATOM   12517 C  C   . LEU D 1 279 ? -19.297 -9.746  -45.648 1.00 35.97  ? 279 LEU D C   1 
ATOM   12518 O  O   . LEU D 1 279 ? -18.991 -9.667  -44.444 1.00 37.08  ? 279 LEU D O   1 
ATOM   12519 C  CB  . LEU D 1 279 ? -21.748 -9.987  -46.193 1.00 33.89  ? 279 LEU D CB  1 
ATOM   12520 C  CG  . LEU D 1 279 ? -23.085 -9.247  -46.181 1.00 42.88  ? 279 LEU D CG  1 
ATOM   12521 C  CD1 . LEU D 1 279 ? -24.255 -10.222 -46.253 1.00 42.02  ? 279 LEU D CD1 1 
ATOM   12522 C  CD2 . LEU D 1 279 ? -23.194 -8.317  -44.967 1.00 34.64  ? 279 LEU D CD2 1 
ATOM   12523 N  N   . PRO D 1 280 ? -18.545 -10.466 -46.492 1.00 38.18  ? 280 PRO D N   1 
ATOM   12524 C  CA  . PRO D 1 280 ? -17.302 -11.096 -45.990 1.00 35.32  ? 280 PRO D CA  1 
ATOM   12525 C  C   . PRO D 1 280 ? -16.329 -10.133 -45.306 1.00 40.10  ? 280 PRO D C   1 
ATOM   12526 O  O   . PRO D 1 280 ? -15.798 -10.450 -44.228 1.00 37.48  ? 280 PRO D O   1 
ATOM   12527 C  CB  . PRO D 1 280 ? -16.686 -11.701 -47.261 1.00 35.49  ? 280 PRO D CB  1 
ATOM   12528 C  CG  . PRO D 1 280 ? -17.830 -11.901 -48.184 1.00 39.64  ? 280 PRO D CG  1 
ATOM   12529 C  CD  . PRO D 1 280 ? -18.787 -10.784 -47.913 1.00 37.83  ? 280 PRO D CD  1 
ATOM   12530 N  N   . LEU D 1 281 ? -16.068 -8.967  -45.912 1.00 35.73  ? 281 LEU D N   1 
ATOM   12531 C  CA  . LEU D 1 281 ? -15.109 -8.030  -45.330 1.00 30.70  ? 281 LEU D CA  1 
ATOM   12532 C  C   . LEU D 1 281 ? -15.665 -7.400  -44.060 1.00 29.79  ? 281 LEU D C   1 
ATOM   12533 O  O   . LEU D 1 281 ? -14.932 -7.190  -43.094 1.00 35.91  ? 281 LEU D O   1 
ATOM   12534 C  CB  . LEU D 1 281 ? -14.722 -6.946  -46.361 1.00 26.41  ? 281 LEU D CB  1 
ATOM   12535 C  CG  . LEU D 1 281 ? -13.886 -5.743  -45.853 1.00 36.11  ? 281 LEU D CG  1 
ATOM   12536 C  CD1 . LEU D 1 281 ? -12.409 -6.096  -45.613 1.00 29.94  ? 281 LEU D CD1 1 
ATOM   12537 C  CD2 . LEU D 1 281 ? -13.999 -4.494  -46.747 1.00 35.48  ? 281 LEU D CD2 1 
ATOM   12538 N  N   . ALA D 1 282 ? -16.954 -7.081  -44.041 1.00 33.74  ? 282 ALA D N   1 
ATOM   12539 C  CA  . ALA D 1 282 ? -17.538 -6.541  -42.821 1.00 33.16  ? 282 ALA D CA  1 
ATOM   12540 C  C   . ALA D 1 282 ? -17.419 -7.540  -41.682 1.00 38.83  ? 282 ALA D C   1 
ATOM   12541 O  O   . ALA D 1 282 ? -17.212 -7.155  -40.524 1.00 39.01  ? 282 ALA D O   1 
ATOM   12542 C  CB  . ALA D 1 282 ? -18.999 -6.166  -43.053 1.00 32.29  ? 282 ALA D CB  1 
ATOM   12543 N  N   . GLU D 1 283 ? -17.549 -8.828  -41.999 1.00 36.07  ? 283 GLU D N   1 
ATOM   12544 C  CA  . GLU D 1 283 ? -17.351 -9.870  -40.995 1.00 44.86  ? 283 GLU D CA  1 
ATOM   12545 C  C   . GLU D 1 283 ? -15.895 -9.920  -40.555 1.00 43.94  ? 283 GLU D C   1 
ATOM   12546 O  O   . GLU D 1 283 ? -15.599 -10.002 -39.356 1.00 41.97  ? 283 GLU D O   1 
ATOM   12547 C  CB  . GLU D 1 283 ? -17.791 -11.230 -41.548 1.00 37.79  ? 283 GLU D CB  1 
ATOM   12548 C  CG  . GLU D 1 283 ? -18.056 -12.286 -40.467 1.00 46.36  ? 283 GLU D CG  1 
ATOM   12549 C  CD  . GLU D 1 283 ? -18.499 -13.638 -41.037 1.00 53.98  ? 283 GLU D CD  1 
ATOM   12550 O  OE1 . GLU D 1 283 ? -19.180 -13.664 -42.087 1.00 59.14  ? 283 GLU D OE1 1 
ATOM   12551 O  OE2 . GLU D 1 283 ? -18.158 -14.682 -40.432 1.00 56.72  ? 283 GLU D OE2 1 
ATOM   12552 N  N   . GLU D 1 284 ? -14.969 -9.877  -41.523 1.00 41.63  ? 284 GLU D N   1 
ATOM   12553 C  CA  . GLU D 1 284 ? -13.549 -9.818  -41.200 1.00 39.41  ? 284 GLU D CA  1 
ATOM   12554 C  C   . GLU D 1 284 ? -13.247 -8.647  -40.274 1.00 41.50  ? 284 GLU D C   1 
ATOM   12555 O  O   . GLU D 1 284 ? -12.481 -8.782  -39.314 1.00 36.17  ? 284 GLU D O   1 
ATOM   12556 C  CB  . GLU D 1 284 ? -12.736 -9.702  -42.484 1.00 38.28  ? 284 GLU D CB  1 
ATOM   12557 C  CG  . GLU D 1 284 ? -11.233 -9.833  -42.291 1.00 52.48  ? 284 GLU D CG  1 
ATOM   12558 C  CD  . GLU D 1 284 ? -10.445 -9.777  -43.614 1.00 62.36  ? 284 GLU D CD  1 
ATOM   12559 O  OE1 . GLU D 1 284 ? -10.963 -10.210 -44.669 1.00 61.64  ? 284 GLU D OE1 1 
ATOM   12560 O  OE2 . GLU D 1 284 ? -9.292  -9.298  -43.594 1.00 72.54  ? 284 GLU D OE2 1 
ATOM   12561 N  N   . LEU D 1 285 ? -13.859 -7.493  -40.535 1.00 38.74  ? 285 LEU D N   1 
ATOM   12562 C  CA  . LEU D 1 285 ? -13.512 -6.274  -39.818 1.00 39.85  ? 285 LEU D CA  1 
ATOM   12563 C  C   . LEU D 1 285 ? -14.297 -6.086  -38.527 1.00 33.89  ? 285 LEU D C   1 
ATOM   12564 O  O   . LEU D 1 285 ? -13.979 -5.173  -37.761 1.00 36.80  ? 285 LEU D O   1 
ATOM   12565 C  CB  . LEU D 1 285 ? -13.725 -5.052  -40.718 1.00 34.87  ? 285 LEU D CB  1 
ATOM   12566 C  CG  . LEU D 1 285 ? -12.799 -4.933  -41.927 1.00 35.25  ? 285 LEU D CG  1 
ATOM   12567 C  CD1 . LEU D 1 285 ? -13.210 -3.753  -42.783 1.00 35.25  ? 285 LEU D CD1 1 
ATOM   12568 C  CD2 . LEU D 1 285 ? -11.364 -4.813  -41.486 1.00 32.81  ? 285 LEU D CD2 1 
ATOM   12569 N  N   . ASP D 1 286 ? -15.308 -6.919  -38.268 1.00 44.30  ? 286 ASP D N   1 
ATOM   12570 C  CA  . ASP D 1 286 ? -16.176 -6.753  -37.104 1.00 37.39  ? 286 ASP D CA  1 
ATOM   12571 C  C   . ASP D 1 286 ? -16.941 -5.431  -37.168 1.00 34.74  ? 286 ASP D C   1 
ATOM   12572 O  O   . ASP D 1 286 ? -17.154 -4.763  -36.153 1.00 33.29  ? 286 ASP D O   1 
ATOM   12573 C  CB  . ASP D 1 286 ? -15.373 -6.873  -35.797 1.00 36.91  ? 286 ASP D CB  1 
ATOM   12574 C  CG  . ASP D 1 286 ? -16.192 -7.453  -34.652 1.00 38.10  ? 286 ASP D CG  1 
ATOM   12575 O  OD1 . ASP D 1 286 ? -17.355 -7.814  -34.890 1.00 35.55  ? 286 ASP D OD1 1 
ATOM   12576 O  OD2 . ASP D 1 286 ? -15.666 -7.549  -33.522 1.00 47.64  ? 286 ASP D OD2 1 
ATOM   12577 N  N   . VAL D 1 287 ? -17.365 -5.051  -38.374 1.00 35.31  ? 287 VAL D N   1 
ATOM   12578 C  CA  . VAL D 1 287 ? -18.152 -3.846  -38.602 1.00 30.70  ? 287 VAL D CA  1 
ATOM   12579 C  C   . VAL D 1 287 ? -19.498 -4.248  -39.181 1.00 35.46  ? 287 VAL D C   1 
ATOM   12580 O  O   . VAL D 1 287 ? -19.569 -5.118  -40.059 1.00 37.70  ? 287 VAL D O   1 
ATOM   12581 C  CB  . VAL D 1 287 ? -17.434 -2.865  -39.550 1.00 35.05  ? 287 VAL D CB  1 
ATOM   12582 C  CG1 . VAL D 1 287 ? -18.382 -1.796  -40.001 1.00 32.11  ? 287 VAL D CG1 1 
ATOM   12583 C  CG2 . VAL D 1 287 ? -16.239 -2.244  -38.866 1.00 30.95  ? 287 VAL D CG2 1 
ATOM   12584 N  N   . ILE D 1 288 ? -20.569 -3.625  -38.688 1.00 34.44  ? 288 ILE D N   1 
ATOM   12585 C  CA  . ILE D 1 288 ? -21.932 -3.964  -39.099 1.00 36.32  ? 288 ILE D CA  1 
ATOM   12586 C  C   . ILE D 1 288 ? -22.423 -2.958  -40.135 1.00 34.67  ? 288 ILE D C   1 
ATOM   12587 O  O   . ILE D 1 288 ? -22.441 -1.749  -39.875 1.00 36.32  ? 288 ILE D O   1 
ATOM   12588 C  CB  . ILE D 1 288 ? -22.883 -4.002  -37.890 1.00 34.52  ? 288 ILE D CB  1 
ATOM   12589 C  CG1 . ILE D 1 288 ? -22.432 -5.045  -36.868 1.00 35.47  ? 288 ILE D CG1 1 
ATOM   12590 C  CG2 . ILE D 1 288 ? -24.322 -4.251  -38.340 1.00 37.12  ? 288 ILE D CG2 1 
ATOM   12591 C  CD1 . ILE D 1 288 ? -23.368 -5.152  -35.714 1.00 33.53  ? 288 ILE D CD1 1 
ATOM   12592 N  N   . ILE D 1 289 ? -22.844 -3.459  -41.292 1.00 32.73  ? 289 ILE D N   1 
ATOM   12593 C  CA  . ILE D 1 289 ? -23.539 -2.661  -42.303 1.00 35.75  ? 289 ILE D CA  1 
ATOM   12594 C  C   . ILE D 1 289 ? -24.995 -2.479  -41.883 1.00 39.71  ? 289 ILE D C   1 
ATOM   12595 O  O   . ILE D 1 289 ? -25.740 -3.461  -41.788 1.00 40.28  ? 289 ILE D O   1 
ATOM   12596 C  CB  . ILE D 1 289 ? -23.472 -3.339  -43.682 1.00 38.86  ? 289 ILE D CB  1 
ATOM   12597 C  CG1 . ILE D 1 289 ? -22.038 -3.557  -44.159 1.00 31.46  ? 289 ILE D CG1 1 
ATOM   12598 C  CG2 . ILE D 1 289 ? -24.300 -2.579  -44.693 1.00 37.70  ? 289 ILE D CG2 1 
ATOM   12599 C  CD1 . ILE D 1 289 ? -21.967 -4.621  -45.203 1.00 29.42  ? 289 ILE D CD1 1 
ATOM   12600 N  N   . CYS D 1 290 ? -25.415 -1.230  -41.672 1.00 37.31  ? 290 CYS D N   1 
ATOM   12601 C  CA  . CYS D 1 290 ? -26.785 -0.923  -41.252 1.00 38.51  ? 290 CYS D CA  1 
ATOM   12602 C  C   . CYS D 1 290 ? -27.401 0.236   -42.047 1.00 39.52  ? 290 CYS D C   1 
ATOM   12603 O  O   . CYS D 1 290 ? -27.197 1.414   -41.703 1.00 38.80  ? 290 CYS D O   1 
ATOM   12604 C  CB  . CYS D 1 290 ? -26.844 -0.634  -39.750 1.00 35.50  ? 290 CYS D CB  1 
ATOM   12605 S  SG  . CYS D 1 290 ? -25.710 0.618   -39.037 1.00 40.65  ? 290 CYS D SG  1 
ATOM   12606 N  N   . PRO D 1 291 ? -28.182 -0.057  -43.096 1.00 39.68  ? 291 PRO D N   1 
ATOM   12607 C  CA  . PRO D 1 291 ? -28.913 1.010   -43.792 1.00 42.52  ? 291 PRO D CA  1 
ATOM   12608 C  C   . PRO D 1 291 ? -29.953 1.656   -42.897 1.00 42.69  ? 291 PRO D C   1 
ATOM   12609 O  O   . PRO D 1 291 ? -30.450 1.050   -41.941 1.00 39.70  ? 291 PRO D O   1 
ATOM   12610 C  CB  . PRO D 1 291 ? -29.569 0.289   -44.979 1.00 40.45  ? 291 PRO D CB  1 
ATOM   12611 C  CG  . PRO D 1 291 ? -29.404 -1.162  -44.713 1.00 45.97  ? 291 PRO D CG  1 
ATOM   12612 C  CD  . PRO D 1 291 ? -28.164 -1.287  -43.894 1.00 44.09  ? 291 PRO D CD  1 
ATOM   12613 N  N   . GLU D 1 292 ? -30.294 2.897   -43.235 1.00 33.29  ? 292 GLU D N   1 
ATOM   12614 C  CA  . GLU D 1 292 ? -31.117 3.739   -42.384 1.00 39.44  ? 292 GLU D CA  1 
ATOM   12615 C  C   . GLU D 1 292 ? -32.548 3.769   -42.911 1.00 43.16  ? 292 GLU D C   1 
ATOM   12616 O  O   . GLU D 1 292 ? -32.778 4.097   -44.081 1.00 45.72  ? 292 GLU D O   1 
ATOM   12617 C  CB  . GLU D 1 292 ? -30.524 5.145   -42.303 1.00 39.62  ? 292 GLU D CB  1 
ATOM   12618 C  CG  . GLU D 1 292 ? -31.482 6.209   -41.845 1.00 37.85  ? 292 GLU D CG  1 
ATOM   12619 C  CD  . GLU D 1 292 ? -30.929 7.593   -42.079 1.00 45.81  ? 292 GLU D CD  1 
ATOM   12620 O  OE1 . GLU D 1 292 ? -30.040 7.738   -42.947 1.00 50.56  ? 292 GLU D OE1 1 
ATOM   12621 O  OE2 . GLU D 1 292 ? -31.380 8.537   -41.405 1.00 35.34  ? 292 GLU D OE2 1 
ATOM   12622 N  N   . ILE D 1 293 ? -33.498 3.408   -42.052 1.00 41.27  ? 293 ILE D N   1 
ATOM   12623 C  CA  . ILE D 1 293 ? -34.923 3.573   -42.330 1.00 39.03  ? 293 ILE D CA  1 
ATOM   12624 C  C   . ILE D 1 293 ? -35.281 4.995   -41.938 1.00 40.99  ? 293 ILE D C   1 
ATOM   12625 O  O   . ILE D 1 293 ? -35.276 5.332   -40.751 1.00 40.58  ? 293 ILE D O   1 
ATOM   12626 C  CB  . ILE D 1 293 ? -35.784 2.570   -41.551 1.00 41.81  ? 293 ILE D CB  1 
ATOM   12627 C  CG1 . ILE D 1 293 ? -35.202 1.158   -41.578 1.00 43.07  ? 293 ILE D CG1 1 
ATOM   12628 C  CG2 . ILE D 1 293 ? -37.221 2.595   -42.055 1.00 48.48  ? 293 ILE D CG2 1 
ATOM   12629 C  CD1 . ILE D 1 293 ? -35.343 0.439   -40.234 1.00 42.27  ? 293 ILE D CD1 1 
ATOM   12630 N  N   . HIS D 1 294 ? -35.581 5.839   -42.921 1.00 42.50  ? 294 HIS D N   1 
ATOM   12631 C  CA  . HIS D 1 294 ? -35.924 7.216   -42.601 1.00 45.54  ? 294 HIS D CA  1 
ATOM   12632 C  C   . HIS D 1 294 ? -37.054 7.706   -43.499 1.00 43.67  ? 294 HIS D C   1 
ATOM   12633 O  O   . HIS D 1 294 ? -37.251 7.213   -44.613 1.00 43.87  ? 294 HIS D O   1 
ATOM   12634 C  CB  . HIS D 1 294 ? -34.672 8.116   -42.681 1.00 41.47  ? 294 HIS D CB  1 
ATOM   12635 C  CG  . HIS D 1 294 ? -34.483 8.803   -43.995 1.00 48.17  ? 294 HIS D CG  1 
ATOM   12636 N  ND1 . HIS D 1 294 ? -34.914 10.093  -44.234 1.00 47.06  ? 294 HIS D ND1 1 
ATOM   12637 C  CD2 . HIS D 1 294 ? -33.902 8.381   -45.144 1.00 53.64  ? 294 HIS D CD2 1 
ATOM   12638 C  CE1 . HIS D 1 294 ? -34.604 10.435  -45.472 1.00 56.19  ? 294 HIS D CE1 1 
ATOM   12639 N  NE2 . HIS D 1 294 ? -33.991 9.413   -46.046 1.00 64.58  ? 294 HIS D NE2 1 
ATOM   12640 N  N   . SER D 1 295 ? -37.821 8.653   -42.962 1.00 41.60  ? 295 SER D N   1 
ATOM   12641 C  CA  . SER D 1 295 ? -38.954 9.306   -43.595 1.00 44.10  ? 295 SER D CA  1 
ATOM   12642 C  C   . SER D 1 295 ? -38.622 9.607   -45.054 1.00 48.44  ? 295 SER D C   1 
ATOM   12643 O  O   . SER D 1 295 ? -37.547 10.146  -45.342 1.00 50.95  ? 295 SER D O   1 
ATOM   12644 C  CB  . SER D 1 295 ? -39.303 10.585  -42.823 1.00 43.39  ? 295 SER D CB  1 
ATOM   12645 O  OG  . SER D 1 295 ? -40.558 11.127  -43.191 1.00 45.04  ? 295 SER D OG  1 
ATOM   12646 N  N   . PRO D 1 296 ? -39.517 9.293   -46.002 1.00 46.43  ? 296 PRO D N   1 
ATOM   12647 C  CA  . PRO D 1 296 ? -40.865 8.806   -45.725 1.00 48.64  ? 296 PRO D CA  1 
ATOM   12648 C  C   . PRO D 1 296 ? -41.013 7.284   -45.730 1.00 47.22  ? 296 PRO D C   1 
ATOM   12649 O  O   . PRO D 1 296 ? -42.143 6.820   -45.856 1.00 44.90  ? 296 PRO D O   1 
ATOM   12650 C  CB  . PRO D 1 296 ? -41.669 9.422   -46.867 1.00 48.76  ? 296 PRO D CB  1 
ATOM   12651 C  CG  . PRO D 1 296 ? -40.734 9.363   -48.005 1.00 51.25  ? 296 PRO D CG  1 
ATOM   12652 C  CD  . PRO D 1 296 ? -39.343 9.577   -47.435 1.00 48.82  ? 296 PRO D CD  1 
ATOM   12653 N  N   . THR D 1 297 ? -39.921 6.524   -45.599 1.00 41.83  ? 297 THR D N   1 
ATOM   12654 C  CA  . THR D 1 297 ? -40.069 5.073   -45.528 1.00 48.06  ? 297 THR D CA  1 
ATOM   12655 C  C   . THR D 1 297 ? -40.462 4.651   -44.116 1.00 45.68  ? 297 THR D C   1 
ATOM   12656 O  O   . THR D 1 297 ? -39.755 4.976   -43.158 1.00 47.48  ? 297 THR D O   1 
ATOM   12657 C  CB  . THR D 1 297 ? -38.790 4.350   -45.933 1.00 45.80  ? 297 THR D CB  1 
ATOM   12658 O  OG1 . THR D 1 297 ? -38.242 4.954   -47.105 1.00 49.42  ? 297 THR D OG1 1 
ATOM   12659 C  CG2 . THR D 1 297 ? -39.090 2.885   -46.218 1.00 49.07  ? 297 THR D CG2 1 
ATOM   12660 N  N   . PRO D 1 298 ? -41.563 3.934   -43.949 1.00 51.83  ? 298 PRO D N   1 
ATOM   12661 C  CA  . PRO D 1 298 ? -41.960 3.453   -42.624 1.00 48.68  ? 298 PRO D CA  1 
ATOM   12662 C  C   . PRO D 1 298 ? -41.347 2.086   -42.334 1.00 50.82  ? 298 PRO D C   1 
ATOM   12663 O  O   . PRO D 1 298 ? -40.749 1.447   -43.202 1.00 47.83  ? 298 PRO D O   1 
ATOM   12664 C  CB  . PRO D 1 298 ? -43.491 3.355   -42.735 1.00 51.50  ? 298 PRO D CB  1 
ATOM   12665 C  CG  . PRO D 1 298 ? -43.819 3.557   -44.229 1.00 55.91  ? 298 PRO D CG  1 
ATOM   12666 C  CD  . PRO D 1 298 ? -42.531 3.548   -44.985 1.00 52.58  ? 298 PRO D CD  1 
ATOM   12667 N  N   . ILE D 1 299 ? -41.490 1.623   -41.089 1.00 46.79  ? 299 ILE D N   1 
ATOM   12668 C  CA  . ILE D 1 299 ? -40.968 0.272   -40.730 1.00 47.67  ? 299 ILE D CA  1 
ATOM   12669 C  C   . ILE D 1 299 ? -41.635 -0.791  -41.614 1.00 47.41  ? 299 ILE D C   1 
ATOM   12670 O  O   . ILE D 1 299 ? -40.936 -1.687  -42.066 1.00 45.87  ? 299 ILE D O   1 
ATOM   12671 C  CB  . ILE D 1 299 ? -41.159 -0.028  -39.232 1.00 51.58  ? 299 ILE D CB  1 
ATOM   12672 C  CG1 . ILE D 1 299 ? -40.082 0.646   -38.379 1.00 53.47  ? 299 ILE D CG1 1 
ATOM   12673 C  CG2 . ILE D 1 299 ? -41.217 -1.525  -38.979 1.00 49.34  ? 299 ILE D CG2 1 
ATOM   12674 C  CD1 . ILE D 1 299 ? -40.534 0.976   -36.977 1.00 47.51  ? 299 ILE D CD1 1 
ATOM   12675 N  N   . LYS D 1 300 ? -42.949 -0.688  -41.831 1.00 50.58  ? 300 LYS D N   1 
ATOM   12676 C  CA  . LYS D 1 300 ? -43.666 -1.656  -42.698 1.00 51.00  ? 300 LYS D CA  1 
ATOM   12677 C  C   . LYS D 1 300 ? -43.647 -1.245  -44.169 1.00 54.11  ? 300 LYS D C   1 
ATOM   12678 O  O   . LYS D 1 300 ? -44.426 -0.349  -44.532 1.00 54.34  ? 300 LYS D O   1 
ATOM   12679 C  CB  . LYS D 1 300 ? -45.108 -1.842  -42.218 1.00 59.16  ? 300 LYS D CB  1 
ATOM   12680 C  CG  . LYS D 1 300 ? -45.426 -3.230  -41.680 1.00 53.80  ? 300 LYS D CG  1 
ATOM   12681 C  CD  . LYS D 1 300 ? -44.563 -4.306  -42.301 1.00 62.96  ? 300 LYS D CD  1 
ATOM   12682 C  CE  . LYS D 1 300 ? -44.887 -5.701  -41.812 1.00 58.08  ? 300 LYS D CE  1 
ATOM   12683 N  NZ  . LYS D 1 300 ? -44.358 -6.734  -42.732 1.00 60.31  ? 300 LYS D NZ  1 
ATOM   12684 N  N   . HIS D 1 301 ? -42.821 -1.909  -44.974 1.00 49.54  ? 301 HIS D N   1 
ATOM   12685 C  CA  . HIS D 1 301 ? -42.535 -1.465  -46.355 1.00 49.68  ? 301 HIS D CA  1 
ATOM   12686 C  C   . HIS D 1 301 ? -41.563 -2.477  -46.944 1.00 51.53  ? 301 HIS D C   1 
ATOM   12687 O  O   . HIS D 1 301 ? -40.729 -3.013  -46.198 1.00 55.96  ? 301 HIS D O   1 
ATOM   12688 C  CB  . HIS D 1 301 ? -41.894 -0.082  -46.338 1.00 53.32  ? 301 HIS D CB  1 
ATOM   12689 C  CG  . HIS D 1 301 ? -41.858 0.635   -47.639 1.00 58.01  ? 301 HIS D CG  1 
ATOM   12690 N  ND1 . HIS D 1 301 ? -40.860 0.445   -48.568 1.00 55.62  ? 301 HIS D ND1 1 
ATOM   12691 C  CD2 . HIS D 1 301 ? -42.673 1.559   -48.149 1.00 52.91  ? 301 HIS D CD2 1 
ATOM   12692 C  CE1 . HIS D 1 301 ? -41.087 1.224   -49.611 1.00 55.27  ? 301 HIS D CE1 1 
ATOM   12693 N  NE2 . HIS D 1 301 ? -42.183 1.909   -49.375 1.00 57.00  ? 301 HIS D NE2 1 
ATOM   12694 N  N   . GLU D 1 302 ? -41.649 -2.721  -48.242 1.00 50.08  ? 302 GLU D N   1 
ATOM   12695 C  CA  . GLU D 1 302 ? -40.813 -3.783  -48.852 1.00 54.52  ? 302 GLU D CA  1 
ATOM   12696 C  C   . GLU D 1 302 ? -39.325 -3.506  -48.606 1.00 55.68  ? 302 GLU D C   1 
ATOM   12697 O  O   . GLU D 1 302 ? -38.566 -4.465  -48.518 1.00 53.61  ? 302 GLU D O   1 
ATOM   12698 C  CB  . GLU D 1 302 ? -41.161 -3.933  -50.333 1.00 56.69  ? 302 GLU D CB  1 
ATOM   12699 C  CG  . GLU D 1 302 ? -40.881 -2.699  -51.165 1.00 65.03  ? 302 GLU D CG  1 
ATOM   12700 C  CD  . GLU D 1 302 ? -41.047 -2.941  -52.655 1.00 67.78  ? 302 GLU D CD  1 
ATOM   12701 O  OE1 . GLU D 1 302 ? -40.379 -3.853  -53.180 1.00 60.83  ? 302 GLU D OE1 1 
ATOM   12702 O  OE2 . GLU D 1 302 ? -41.850 -2.223  -53.281 1.00 67.52  ? 302 GLU D OE2 1 
ATOM   12703 N  N   . VAL D 1 303 ? -38.940 -2.240  -48.478 1.00 53.25  ? 303 VAL D N   1 
ATOM   12704 C  CA  . VAL D 1 303 ? -37.500 -1.900  -48.300 1.00 52.17  ? 303 VAL D CA  1 
ATOM   12705 C  C   . VAL D 1 303 ? -37.009 -2.522  -46.992 1.00 51.47  ? 303 VAL D C   1 
ATOM   12706 O  O   . VAL D 1 303 ? -35.956 -3.150  -47.008 1.00 52.94  ? 303 VAL D O   1 
ATOM   12707 C  CB  . VAL D 1 303 ? -37.267 -0.382  -48.327 1.00 59.60  ? 303 VAL D CB  1 
ATOM   12708 C  CG1 . VAL D 1 303 ? -35.880 -0.010  -47.828 1.00 54.35  ? 303 VAL D CG1 1 
ATOM   12709 C  CG2 . VAL D 1 303 ? -37.516 0.202   -49.709 1.00 56.45  ? 303 VAL D CG2 1 
ATOM   12710 N  N   . VAL D 1 304 ? -37.768 -2.362  -45.914 1.00 51.04  ? 304 VAL D N   1 
ATOM   12711 C  CA  . VAL D 1 304 ? -37.386 -2.997  -44.625 1.00 44.43  ? 304 VAL D CA  1 
ATOM   12712 C  C   . VAL D 1 304 ? -37.494 -4.507  -44.787 1.00 47.81  ? 304 VAL D C   1 
ATOM   12713 O  O   . VAL D 1 304 ? -36.561 -5.203  -44.396 1.00 47.58  ? 304 VAL D O   1 
ATOM   12714 C  CB  . VAL D 1 304 ? -38.251 -2.495  -43.461 1.00 46.14  ? 304 VAL D CB  1 
ATOM   12715 C  CG1 . VAL D 1 304 ? -37.827 -3.118  -42.142 1.00 46.80  ? 304 VAL D CG1 1 
ATOM   12716 C  CG2 . VAL D 1 304 ? -38.226 -0.978  -43.367 1.00 49.34  ? 304 VAL D CG2 1 
ATOM   12717 N  N   . ASP D 1 305 ? -38.596 -4.964  -45.373 1.00 51.09  ? 305 ASP D N   1 
ATOM   12718 C  CA  . ASP D 1 305 ? -38.816 -6.421  -45.541 1.00 51.48  ? 305 ASP D CA  1 
ATOM   12719 C  C   . ASP D 1 305 ? -37.640 -7.018  -46.314 1.00 49.82  ? 305 ASP D C   1 
ATOM   12720 O  O   . ASP D 1 305 ? -37.210 -8.116  -45.957 1.00 51.54  ? 305 ASP D O   1 
ATOM   12721 C  CB  . ASP D 1 305 ? -40.169 -6.691  -46.197 1.00 53.20  ? 305 ASP D CB  1 
ATOM   12722 C  CG  . ASP D 1 305 ? -41.323 -6.620  -45.218 1.00 55.92  ? 305 ASP D CG  1 
ATOM   12723 O  OD1 . ASP D 1 305 ? -41.175 -7.156  -44.105 1.00 57.01  ? 305 ASP D OD1 1 
ATOM   12724 O  OD2 . ASP D 1 305 ? -42.352 -6.025  -45.575 1.00 60.61  ? 305 ASP D OD2 1 
ATOM   12725 N  N   . ASP D 1 306 ? -37.134 -6.305  -47.322 1.00 55.36  ? 306 ASP D N   1 
ATOM   12726 C  CA  . ASP D 1 306 ? -36.057 -6.864  -48.128 1.00 54.26  ? 306 ASP D CA  1 
ATOM   12727 C  C   . ASP D 1 306 ? -34.739 -6.891  -47.359 1.00 50.96  ? 306 ASP D C   1 
ATOM   12728 O  O   . ASP D 1 306 ? -33.923 -7.795  -47.569 1.00 51.05  ? 306 ASP D O   1 
ATOM   12729 C  CB  . ASP D 1 306 ? -35.938 -6.080  -49.438 1.00 57.64  ? 306 ASP D CB  1 
ATOM   12730 C  CG  . ASP D 1 306 ? -36.983 -6.506  -50.468 1.00 60.60  ? 306 ASP D CG  1 
ATOM   12731 O  OD1 . ASP D 1 306 ? -38.129 -6.805  -50.069 1.00 62.30  ? 306 ASP D OD1 1 
ATOM   12732 O  OD2 . ASP D 1 306 ? -36.664 -6.520  -51.678 1.00 69.75  ? 306 ASP D OD2 1 
ATOM   12733 N  N   . TYR D 1 307 ? -34.515 -5.930  -46.459 1.00 49.01  ? 307 TYR D N   1 
ATOM   12734 C  CA  . TYR D 1 307 ? -33.350 -6.003  -45.584 1.00 48.36  ? 307 TYR D CA  1 
ATOM   12735 C  C   . TYR D 1 307 ? -33.408 -7.261  -44.724 1.00 52.34  ? 307 TYR D C   1 
ATOM   12736 O  O   . TYR D 1 307 ? -32.501 -8.101  -44.761 1.00 51.79  ? 307 TYR D O   1 
ATOM   12737 C  CB  . TYR D 1 307 ? -33.262 -4.751  -44.704 1.00 48.12  ? 307 TYR D CB  1 
ATOM   12738 C  CG  . TYR D 1 307 ? -33.023 -3.466  -45.462 1.00 50.88  ? 307 TYR D CG  1 
ATOM   12739 C  CD1 . TYR D 1 307 ? -32.504 -3.480  -46.742 1.00 49.95  ? 307 TYR D CD1 1 
ATOM   12740 C  CD2 . TYR D 1 307 ? -33.329 -2.243  -44.901 1.00 46.65  ? 307 TYR D CD2 1 
ATOM   12741 C  CE1 . TYR D 1 307 ? -32.287 -2.309  -47.442 1.00 50.41  ? 307 TYR D CE1 1 
ATOM   12742 C  CE2 . TYR D 1 307 ? -33.121 -1.069  -45.595 1.00 49.42  ? 307 TYR D CE2 1 
ATOM   12743 C  CZ  . TYR D 1 307 ? -32.595 -1.108  -46.862 1.00 49.18  ? 307 TYR D CZ  1 
ATOM   12744 O  OH  . TYR D 1 307 ? -32.389 0.064   -47.550 1.00 56.44  ? 307 TYR D OH  1 
ATOM   12745 N  N   . ILE D 1 308 ? -34.493 -7.414  -43.955 1.00 54.68  ? 308 ILE D N   1 
ATOM   12746 C  CA  . ILE D 1 308 ? -34.674 -8.595  -43.110 1.00 53.02  ? 308 ILE D CA  1 
ATOM   12747 C  C   . ILE D 1 308 ? -34.554 -9.867  -43.932 1.00 52.72  ? 308 ILE D C   1 
ATOM   12748 O  O   . ILE D 1 308 ? -33.924 -10.844 -43.507 1.00 51.21  ? 308 ILE D O   1 
ATOM   12749 C  CB  . ILE D 1 308 ? -36.026 -8.520  -42.381 1.00 48.53  ? 308 ILE D CB  1 
ATOM   12750 C  CG1 . ILE D 1 308 ? -36.314 -7.067  -41.995 1.00 50.20  ? 308 ILE D CG1 1 
ATOM   12751 C  CG2 . ILE D 1 308 ? -36.016 -9.428  -41.168 1.00 49.09  ? 308 ILE D CG2 1 
ATOM   12752 C  CD1 . ILE D 1 308 ? -37.480 -6.873  -41.048 1.00 53.95  ? 308 ILE D CD1 1 
ATOM   12753 N  N   . ALA D 1 309 ? -35.138 -9.871  -45.131 1.00 50.88  ? 309 ALA D N   1 
ATOM   12754 C  CA  . ALA D 1 309 ? -34.992 -11.028 -46.006 1.00 52.54  ? 309 ALA D CA  1 
ATOM   12755 C  C   . ALA D 1 309 ? -33.531 -11.299 -46.334 1.00 54.86  ? 309 ALA D C   1 
ATOM   12756 O  O   . ALA D 1 309 ? -33.156 -12.454 -46.570 1.00 58.66  ? 309 ALA D O   1 
ATOM   12757 C  CB  . ALA D 1 309 ? -35.801 -10.830 -47.289 1.00 49.52  ? 309 ALA D CB  1 
ATOM   12758 N  N   . LEU D 1 310 ? -32.691 -10.258 -46.367 1.00 50.48  ? 310 LEU D N   1 
ATOM   12759 C  CA  . LEU D 1 310 ? -31.272 -10.492 -46.610 1.00 50.23  ? 310 LEU D CA  1 
ATOM   12760 C  C   . LEU D 1 310 ? -30.605 -11.072 -45.371 1.00 47.20  ? 310 LEU D C   1 
ATOM   12761 O  O   . LEU D 1 310 ? -29.804 -12.009 -45.476 1.00 50.61  ? 310 LEU D O   1 
ATOM   12762 C  CB  . LEU D 1 310 ? -30.589 -9.197  -47.067 1.00 48.70  ? 310 LEU D CB  1 
ATOM   12763 C  CG  . LEU D 1 310 ? -29.089 -9.131  -47.375 1.00 41.30  ? 310 LEU D CG  1 
ATOM   12764 C  CD1 . LEU D 1 310 ? -28.789 -7.806  -48.036 1.00 51.42  ? 310 LEU D CD1 1 
ATOM   12765 C  CD2 . LEU D 1 310 ? -28.210 -9.254  -46.159 1.00 44.93  ? 310 LEU D CD2 1 
ATOM   12766 N  N   . ILE D 1 311 ? -30.906 -10.513 -44.191 1.00 51.41  ? 311 ILE D N   1 
ATOM   12767 C  CA  . ILE D 1 311 ? -30.400 -11.076 -42.940 1.00 49.33  ? 311 ILE D CA  1 
ATOM   12768 C  C   . ILE D 1 311 ? -30.670 -12.575 -42.890 1.00 50.81  ? 311 ILE D C   1 
ATOM   12769 O  O   . ILE D 1 311 ? -29.755 -13.380 -42.689 1.00 54.64  ? 311 ILE D O   1 
ATOM   12770 C  CB  . ILE D 1 311 ? -31.025 -10.358 -41.730 1.00 50.05  ? 311 ILE D CB  1 
ATOM   12771 C  CG1 . ILE D 1 311 ? -30.939 -8.841  -41.878 1.00 51.17  ? 311 ILE D CG1 1 
ATOM   12772 C  CG2 . ILE D 1 311 ? -30.366 -10.805 -40.442 1.00 47.79  ? 311 ILE D CG2 1 
ATOM   12773 C  CD1 . ILE D 1 311 ? -31.255 -8.070  -40.594 1.00 44.27  ? 311 ILE D CD1 1 
ATOM   12774 N  N   . ARG D 1 312 ? -31.933 -12.970 -43.108 1.00 55.36  ? 312 ARG D N   1 
ATOM   12775 C  CA  . ARG D 1 312 ? -32.321 -14.376 -43.002 1.00 54.70  ? 312 ARG D CA  1 
ATOM   12776 C  C   . ARG D 1 312 ? -31.697 -15.221 -44.107 1.00 56.14  ? 312 ARG D C   1 
ATOM   12777 O  O   . ARG D 1 312 ? -31.312 -16.374 -43.872 1.00 56.86  ? 312 ARG D O   1 
ATOM   12778 C  CB  . ARG D 1 312 ? -33.844 -14.512 -43.033 1.00 60.51  ? 312 ARG D CB  1 
ATOM   12779 C  CG  . ARG D 1 312 ? -34.590 -13.465 -42.218 1.00 59.10  ? 312 ARG D CG  1 
ATOM   12780 C  CD  . ARG D 1 312 ? -36.016 -13.900 -41.880 1.00 61.34  ? 312 ARG D CD  1 
ATOM   12781 N  NE  . ARG D 1 312 ? -36.507 -13.193 -40.703 1.00 63.01  ? 312 ARG D NE  1 
ATOM   12782 C  CZ  . ARG D 1 312 ? -37.776 -12.877 -40.485 1.00 60.72  ? 312 ARG D CZ  1 
ATOM   12783 N  NH1 . ARG D 1 312 ? -38.735 -13.249 -41.317 1.00 59.93  ? 312 ARG D NH1 1 
ATOM   12784 N  NH2 . ARG D 1 312 ? -38.089 -12.154 -39.412 1.00 66.05  ? 312 ARG D NH2 1 
ATOM   12785 N  N   . ARG D 1 313 ? -31.592 -14.675 -45.318 1.00 52.53  ? 313 ARG D N   1 
ATOM   12786 C  CA  . ARG D 1 313 ? -31.026 -15.445 -46.421 1.00 51.18  ? 313 ARG D CA  1 
ATOM   12787 C  C   . ARG D 1 313 ? -29.542 -15.714 -46.194 1.00 53.27  ? 313 ARG D C   1 
ATOM   12788 O  O   . ARG D 1 313 ? -29.092 -16.865 -46.234 1.00 54.45  ? 313 ARG D O   1 
ATOM   12789 C  CB  . ARG D 1 313 ? -31.249 -14.705 -47.741 1.00 54.42  ? 313 ARG D CB  1 
ATOM   12790 C  CG  . ARG D 1 313 ? -31.001 -15.544 -48.999 1.00 51.19  ? 313 ARG D CG  1 
ATOM   12791 C  CD  . ARG D 1 313 ? -31.349 -14.771 -50.276 1.00 54.91  ? 313 ARG D CD  1 
ATOM   12792 N  NE  . ARG D 1 313 ? -30.612 -13.519 -50.404 1.00 58.62  ? 313 ARG D NE  1 
ATOM   12793 C  CZ  . ARG D 1 313 ? -31.157 -12.316 -50.302 1.00 54.70  ? 313 ARG D CZ  1 
ATOM   12794 N  NH1 . ARG D 1 313 ? -32.441 -12.163 -50.027 1.00 53.43  ? 313 ARG D NH1 1 
ATOM   12795 N  NH2 . ARG D 1 313 ? -30.394 -11.240 -50.476 1.00 56.55  ? 313 ARG D NH2 1 
ATOM   12796 N  N   . THR D 1 314 ? -28.770 -14.662 -45.928 1.00 51.72  ? 314 THR D N   1 
ATOM   12797 C  CA  . THR D 1 314 ? -27.322 -14.802 -45.797 1.00 51.26  ? 314 THR D CA  1 
ATOM   12798 C  C   . THR D 1 314 ? -26.915 -15.440 -44.472 1.00 47.91  ? 314 THR D C   1 
ATOM   12799 O  O   . THR D 1 314 ? -25.818 -15.997 -44.365 1.00 46.53  ? 314 THR D O   1 
ATOM   12800 C  CB  . THR D 1 314 ? -26.679 -13.431 -45.909 1.00 46.28  ? 314 THR D CB  1 
ATOM   12801 O  OG1 . THR D 1 314 ? -27.055 -12.658 -44.760 1.00 43.80  ? 314 THR D OG1 1 
ATOM   12802 C  CG2 . THR D 1 314 ? -27.162 -12.733 -47.156 1.00 49.52  ? 314 THR D CG2 1 
ATOM   12803 N  N   . GLY D 1 315 ? -27.754 -15.329 -43.448 1.00 49.54  ? 315 GLY D N   1 
ATOM   12804 C  CA  . GLY D 1 315 ? -27.339 -15.699 -42.110 1.00 51.52  ? 315 GLY D CA  1 
ATOM   12805 C  C   . GLY D 1 315 ? -26.358 -14.760 -41.437 1.00 47.77  ? 315 GLY D C   1 
ATOM   12806 O  O   . GLY D 1 315 ? -25.817 -15.118 -40.387 1.00 45.57  ? 315 GLY D O   1 
ATOM   12807 N  N   . THR D 1 316 ? -26.126 -13.563 -41.984 1.00 44.95  ? 316 THR D N   1 
ATOM   12808 C  CA  . THR D 1 316 ? -25.068 -12.695 -41.472 1.00 45.00  ? 316 THR D CA  1 
ATOM   12809 C  C   . THR D 1 316 ? -25.402 -12.158 -40.081 1.00 44.17  ? 316 THR D C   1 
ATOM   12810 O  O   . THR D 1 316 ? -26.565 -11.922 -39.736 1.00 47.55  ? 316 THR D O   1 
ATOM   12811 C  CB  . THR D 1 316 ? -24.809 -11.515 -42.432 1.00 42.50  ? 316 THR D CB  1 
ATOM   12812 O  OG1 . THR D 1 316 ? -23.715 -10.729 -41.944 1.00 42.02  ? 316 THR D OG1 1 
ATOM   12813 C  CG2 . THR D 1 316 ? -26.025 -10.614 -42.527 1.00 40.74  ? 316 THR D CG2 1 
ATOM   12814 N  N   . LYS D 1 317 ? -24.358 -11.971 -39.276 1.00 44.03  ? 317 LYS D N   1 
ATOM   12815 C  CA  . LYS D 1 317 ? -24.456 -11.278 -37.998 1.00 46.30  ? 317 LYS D CA  1 
ATOM   12816 C  C   . LYS D 1 317 ? -24.051 -9.822  -38.116 1.00 39.65  ? 317 LYS D C   1 
ATOM   12817 O  O   . LYS D 1 317 ? -24.116 -9.084  -37.132 1.00 37.47  ? 317 LYS D O   1 
ATOM   12818 C  CB  . LYS D 1 317 ? -23.582 -11.975 -36.948 1.00 45.05  ? 317 LYS D CB  1 
ATOM   12819 C  CG  . LYS D 1 317 ? -23.971 -13.425 -36.716 1.00 45.45  ? 317 LYS D CG  1 
ATOM   12820 C  CD  . LYS D 1 317 ? -25.423 -13.526 -36.219 1.00 47.23  ? 317 LYS D CD  1 
ATOM   12821 C  CE  . LYS D 1 317 ? -26.167 -14.740 -36.800 1.00 44.70  ? 317 LYS D CE  1 
ATOM   12822 N  NZ  . LYS D 1 317 ? -25.358 -16.001 -36.842 1.00 41.82  ? 317 LYS D NZ  1 
ATOM   12823 N  N   . HIS D 1 318 ? -23.646 -9.404  -39.308 1.00 44.49  ? 318 HIS D N   1 
ATOM   12824 C  CA  . HIS D 1 318 ? -23.167 -8.066  -39.606 1.00 38.11  ? 318 HIS D CA  1 
ATOM   12825 C  C   . HIS D 1 318 ? -24.016 -7.410  -40.678 1.00 40.17  ? 318 HIS D C   1 
ATOM   12826 O  O   . HIS D 1 318 ? -23.493 -6.848  -41.637 1.00 41.79  ? 318 HIS D O   1 
ATOM   12827 C  CB  . HIS D 1 318 ? -21.717 -8.098  -40.060 1.00 34.09  ? 318 HIS D CB  1 
ATOM   12828 C  CG  . HIS D 1 318 ? -20.765 -8.541  -39.004 1.00 40.42  ? 318 HIS D CG  1 
ATOM   12829 N  ND1 . HIS D 1 318 ? -20.339 -9.845  -38.889 1.00 42.63  ? 318 HIS D ND1 1 
ATOM   12830 C  CD2 . HIS D 1 318 ? -20.144 -7.851  -38.019 1.00 43.70  ? 318 HIS D CD2 1 
ATOM   12831 C  CE1 . HIS D 1 318 ? -19.502 -9.942  -37.873 1.00 45.57  ? 318 HIS D CE1 1 
ATOM   12832 N  NE2 . HIS D 1 318 ? -19.361 -8.744  -37.332 1.00 43.17  ? 318 HIS D NE2 1 
ATOM   12833 N  N   . PHE D 1 319 ? -25.335 -7.516  -40.557 1.00 39.94  ? 319 PHE D N   1 
ATOM   12834 C  CA  . PHE D 1 319 ? -26.239 -6.647  -41.301 1.00 40.58  ? 319 PHE D CA  1 
ATOM   12835 C  C   . PHE D 1 319 ? -27.461 -6.425  -40.439 1.00 40.66  ? 319 PHE D C   1 
ATOM   12836 O  O   . PHE D 1 319 ? -28.181 -7.377  -40.128 1.00 42.62  ? 319 PHE D O   1 
ATOM   12837 C  CB  . PHE D 1 319 ? -26.653 -7.221  -42.653 1.00 45.01  ? 319 PHE D CB  1 
ATOM   12838 C  CG  . PHE D 1 319 ? -27.538 -6.298  -43.446 1.00 43.67  ? 319 PHE D CG  1 
ATOM   12839 C  CD1 . PHE D 1 319 ? -27.000 -5.209  -44.118 1.00 44.48  ? 319 PHE D CD1 1 
ATOM   12840 C  CD2 . PHE D 1 319 ? -28.907 -6.497  -43.497 1.00 47.39  ? 319 PHE D CD2 1 
ATOM   12841 C  CE1 . PHE D 1 319 ? -27.803 -4.353  -44.840 1.00 41.54  ? 319 PHE D CE1 1 
ATOM   12842 C  CE2 . PHE D 1 319 ? -29.720 -5.640  -44.213 1.00 47.99  ? 319 PHE D CE2 1 
ATOM   12843 C  CZ  . PHE D 1 319 ? -29.167 -4.565  -44.886 1.00 49.09  ? 319 PHE D CZ  1 
ATOM   12844 N  N   . GLY D 1 320 ? -27.679 -5.176  -40.055 1.00 41.58  ? 320 GLY D N   1 
ATOM   12845 C  CA  . GLY D 1 320 ? -28.774 -4.834  -39.183 1.00 39.41  ? 320 GLY D CA  1 
ATOM   12846 C  C   . GLY D 1 320 ? -29.591 -3.719  -39.782 1.00 41.75  ? 320 GLY D C   1 
ATOM   12847 O  O   . GLY D 1 320 ? -29.431 -3.389  -40.959 1.00 45.36  ? 320 GLY D O   1 
ATOM   12848 N  N   . LEU D 1 321 ? -30.474 -3.139  -38.988 1.00 35.02  ? 321 LEU D N   1 
ATOM   12849 C  CA  . LEU D 1 321 ? -31.238 -1.982  -39.401 1.00 40.18  ? 321 LEU D CA  1 
ATOM   12850 C  C   . LEU D 1 321 ? -30.793 -0.798  -38.572 1.00 40.02  ? 321 LEU D C   1 
ATOM   12851 O  O   . LEU D 1 321 ? -30.528 -0.932  -37.370 1.00 38.05  ? 321 LEU D O   1 
ATOM   12852 C  CB  . LEU D 1 321 ? -32.746 -2.200  -39.236 1.00 43.31  ? 321 LEU D CB  1 
ATOM   12853 C  CG  . LEU D 1 321 ? -33.264 -3.539  -39.773 1.00 45.74  ? 321 LEU D CG  1 
ATOM   12854 C  CD1 . LEU D 1 321 ? -34.759 -3.738  -39.490 1.00 48.40  ? 321 LEU D CD1 1 
ATOM   12855 C  CD2 . LEU D 1 321 ? -32.977 -3.666  -41.252 1.00 45.20  ? 321 LEU D CD2 1 
ATOM   12856 N  N   . LEU D 1 322 ? -30.641 0.340   -39.236 1.00 39.90  ? 322 LEU D N   1 
ATOM   12857 C  CA  . LEU D 1 322 ? -30.491 1.615   -38.561 1.00 38.10  ? 322 LEU D CA  1 
ATOM   12858 C  C   . LEU D 1 322 ? -31.834 2.317   -38.634 1.00 39.90  ? 322 LEU D C   1 
ATOM   12859 O  O   . LEU D 1 322 ? -32.411 2.448   -39.720 1.00 39.79  ? 322 LEU D O   1 
ATOM   12860 C  CB  . LEU D 1 322 ? -29.393 2.477   -39.196 1.00 35.63  ? 322 LEU D CB  1 
ATOM   12861 C  CG  . LEU D 1 322 ? -29.042 3.740   -38.389 1.00 39.01  ? 322 LEU D CG  1 
ATOM   12862 C  CD1 . LEU D 1 322 ? -27.634 4.241   -38.693 1.00 36.38  ? 322 LEU D CD1 1 
ATOM   12863 C  CD2 . LEU D 1 322 ? -30.036 4.853   -38.627 1.00 35.44  ? 322 LEU D CD2 1 
ATOM   12864 N  N   . LEU D 1 323 ? -32.306 2.797   -37.491 1.00 35.72  ? 323 LEU D N   1 
ATOM   12865 C  CA  . LEU D 1 323 ? -33.610 3.426   -37.372 1.00 36.94  ? 323 LEU D CA  1 
ATOM   12866 C  C   . LEU D 1 323 ? -33.457 4.931   -37.192 1.00 39.10  ? 323 LEU D C   1 
ATOM   12867 O  O   . LEU D 1 323 ? -32.600 5.393   -36.434 1.00 40.40  ? 323 LEU D O   1 
ATOM   12868 C  CB  . LEU D 1 323 ? -34.374 2.815   -36.195 1.00 38.68  ? 323 LEU D CB  1 
ATOM   12869 C  CG  . LEU D 1 323 ? -35.891 2.732   -36.258 1.00 40.86  ? 323 LEU D CG  1 
ATOM   12870 C  CD1 . LEU D 1 323 ? -36.356 2.637   -37.688 1.00 44.71  ? 323 LEU D CD1 1 
ATOM   12871 C  CD2 . LEU D 1 323 ? -36.348 1.509   -35.479 1.00 46.41  ? 323 LEU D CD2 1 
ATOM   12872 N  N   . ASP D 1 324 ? -34.318 5.690   -37.872 1.00 40.31  ? 324 ASP D N   1 
ATOM   12873 C  CA  . ASP D 1 324 ? -34.316 7.169   -37.746 1.00 37.90  ? 324 ASP D CA  1 
ATOM   12874 C  C   . ASP D 1 324 ? -35.624 7.619   -37.102 1.00 40.48  ? 324 ASP D C   1 
ATOM   12875 O  O   . ASP D 1 324 ? -36.673 7.447   -37.722 1.00 39.11  ? 324 ASP D O   1 
ATOM   12876 C  CB  . ASP D 1 324 ? -34.134 7.873   -39.088 1.00 43.86  ? 324 ASP D CB  1 
ATOM   12877 C  CG  . ASP D 1 324 ? -33.839 9.354   -38.956 1.00 40.06  ? 324 ASP D CG  1 
ATOM   12878 O  OD1 . ASP D 1 324 ? -34.786 10.114  -38.713 1.00 39.14  ? 324 ASP D OD1 1 
ATOM   12879 O  OD2 . ASP D 1 324 ? -32.667 9.729   -39.109 1.00 41.78  ? 324 ASP D OD2 1 
ATOM   12880 N  N   . THR D 1 325 ? -35.535 8.266   -35.949 1.00 39.44  ? 325 THR D N   1 
ATOM   12881 C  CA  . THR D 1 325 ? -36.734 8.667   -35.170 1.00 41.82  ? 325 THR D CA  1 
ATOM   12882 C  C   . THR D 1 325 ? -37.630 9.659   -35.924 1.00 39.92  ? 325 THR D C   1 
ATOM   12883 O  O   . THR D 1 325 ? -38.664 10.014  -35.373 1.00 38.92  ? 325 THR D O   1 
ATOM   12884 C  CB  . THR D 1 325 ? -36.284 9.197   -33.807 1.00 40.55  ? 325 THR D CB  1 
ATOM   12885 O  OG1 . THR D 1 325 ? -35.286 10.189  -34.028 1.00 42.12  ? 325 THR D OG1 1 
ATOM   12886 C  CG2 . THR D 1 325 ? -35.735 8.103   -32.918 1.00 41.14  ? 325 THR D CG2 1 
ATOM   12887 N  N   . GLY D 1 326 ? -37.247 10.087  -37.124 1.00 41.84  ? 326 GLY D N   1 
ATOM   12888 C  CA  . GLY D 1 326 ? -38.119 10.963  -37.933 1.00 39.46  ? 326 GLY D CA  1 
ATOM   12889 C  C   . GLY D 1 326 ? -39.351 10.215  -38.406 1.00 38.75  ? 326 GLY D C   1 
ATOM   12890 O  O   . GLY D 1 326 ? -40.356 10.853  -38.717 1.00 36.77  ? 326 GLY D O   1 
ATOM   12891 N  N   . ILE D 1 327 ? -39.253 8.894   -38.442 1.00 44.08  ? 327 ILE D N   1 
ATOM   12892 C  CA  . ILE D 1 327 ? -40.389 8.053   -38.906 1.00 48.05  ? 327 ILE D CA  1 
ATOM   12893 C  C   . ILE D 1 327 ? -41.487 8.067   -37.840 1.00 46.35  ? 327 ILE D C   1 
ATOM   12894 O  O   . ILE D 1 327 ? -42.602 7.694   -38.173 1.00 49.62  ? 327 ILE D O   1 
ATOM   12895 C  CB  . ILE D 1 327 ? -39.902 6.633   -39.253 1.00 47.33  ? 327 ILE D CB  1 
ATOM   12896 C  CG1 . ILE D 1 327 ? -39.475 5.846   -38.013 1.00 40.84  ? 327 ILE D CG1 1 
ATOM   12897 C  CG2 . ILE D 1 327 ? -38.803 6.686   -40.301 1.00 41.75  ? 327 ILE D CG2 1 
ATOM   12898 C  CD1 . ILE D 1 327 ? -39.370 4.365   -38.254 1.00 43.08  ? 327 ILE D CD1 1 
ATOM   12899 N  N   . PHE D 1 328 ? -41.166 8.480   -36.613 1.00 47.77  ? 328 PHE D N   1 
ATOM   12900 C  CA  . PHE D 1 328 ? -42.169 8.587   -35.554 1.00 46.97  ? 328 PHE D CA  1 
ATOM   12901 C  C   . PHE D 1 328 ? -42.702 10.000  -35.389 1.00 47.55  ? 328 PHE D C   1 
ATOM   12902 O  O   . PHE D 1 328 ? -43.469 10.249  -34.457 1.00 46.94  ? 328 PHE D O   1 
ATOM   12903 C  CB  . PHE D 1 328 ? -41.602 8.121   -34.208 1.00 41.13  ? 328 PHE D CB  1 
ATOM   12904 C  CG  . PHE D 1 328 ? -41.035 6.740   -34.236 1.00 45.31  ? 328 PHE D CG  1 
ATOM   12905 C  CD1 . PHE D 1 328 ? -41.792 5.675   -34.680 1.00 44.07  ? 328 PHE D CD1 1 
ATOM   12906 C  CD2 . PHE D 1 328 ? -39.739 6.501   -33.816 1.00 43.51  ? 328 PHE D CD2 1 
ATOM   12907 C  CE1 . PHE D 1 328 ? -41.263 4.398   -34.712 1.00 44.23  ? 328 PHE D CE1 1 
ATOM   12908 C  CE2 . PHE D 1 328 ? -39.209 5.223   -33.852 1.00 39.37  ? 328 PHE D CE2 1 
ATOM   12909 C  CZ  . PHE D 1 328 ? -39.970 4.175   -34.299 1.00 37.59  ? 328 PHE D CZ  1 
ATOM   12910 N  N   . GLN D 1 329 ? -42.285 10.933  -36.239 1.00 41.39  ? 329 GLN D N   1 
ATOM   12911 C  CA  . GLN D 1 329 ? -42.770 12.302  -36.144 1.00 44.28  ? 329 GLN D CA  1 
ATOM   12912 C  C   . GLN D 1 329 ? -44.294 12.334  -36.192 1.00 48.22  ? 329 GLN D C   1 
ATOM   12913 O  O   . GLN D 1 329 ? -44.921 11.660  -37.011 1.00 45.22  ? 329 GLN D O   1 
ATOM   12914 C  CB  . GLN D 1 329 ? -42.190 13.143  -37.278 1.00 45.66  ? 329 GLN D CB  1 
ATOM   12915 C  CG  . GLN D 1 329 ? -42.684 14.563  -37.281 1.00 44.47  ? 329 GLN D CG  1 
ATOM   12916 C  CD  . GLN D 1 329 ? -42.091 15.394  -38.400 1.00 49.60  ? 329 GLN D CD  1 
ATOM   12917 O  OE1 . GLN D 1 329 ? -41.616 14.865  -39.411 1.00 51.12  ? 329 GLN D OE1 1 
ATOM   12918 N  NE2 . GLN D 1 329 ? -42.116 16.710  -38.225 1.00 48.38  ? 329 GLN D NE2 1 
ATOM   12919 N  N   . ASP D 1 330 ? -44.892 13.121  -35.298 1.00 50.91  ? 330 ASP D N   1 
ATOM   12920 C  CA  . ASP D 1 330 ? -46.343 13.162  -35.172 1.00 51.61  ? 330 ASP D CA  1 
ATOM   12921 C  C   . ASP D 1 330 ? -46.889 14.581  -35.271 1.00 51.12  ? 330 ASP D C   1 
ATOM   12922 O  O   . ASP D 1 330 ? -48.096 14.780  -35.096 1.00 54.26  ? 330 ASP D O   1 
ATOM   12923 C  CB  . ASP D 1 330 ? -46.782 12.481  -33.859 1.00 48.81  ? 330 ASP D CB  1 
ATOM   12924 C  CG  . ASP D 1 330 ? -46.685 13.393  -32.637 1.00 47.30  ? 330 ASP D CG  1 
ATOM   12925 O  OD1 . ASP D 1 330 ? -45.868 14.334  -32.632 1.00 50.77  ? 330 ASP D OD1 1 
ATOM   12926 O  OD2 . ASP D 1 330 ? -47.405 13.133  -31.647 1.00 50.52  ? 330 ASP D OD2 1 
ATOM   12927 N  N   . ARG D 1 331 ? -46.038 15.560  -35.562 1.00 43.82  ? 331 ARG D N   1 
ATOM   12928 C  CA  . ARG D 1 331 ? -46.419 16.960  -35.666 1.00 46.50  ? 331 ARG D CA  1 
ATOM   12929 C  C   . ARG D 1 331 ? -45.523 17.616  -36.711 1.00 48.54  ? 331 ARG D C   1 
ATOM   12930 O  O   . ARG D 1 331 ? -44.402 17.146  -36.942 1.00 45.24  ? 331 ARG D O   1 
ATOM   12931 C  CB  . ARG D 1 331 ? -46.304 17.661  -34.305 1.00 46.92  ? 331 ARG D CB  1 
ATOM   12932 C  CG  . ARG D 1 331 ? -47.424 17.263  -33.336 1.00 49.96  ? 331 ARG D CG  1 
ATOM   12933 C  CD  . ARG D 1 331 ? -47.106 17.569  -31.881 1.00 54.02  ? 331 ARG D CD  1 
ATOM   12934 N  NE  . ARG D 1 331 ? -45.719 17.290  -31.525 1.00 55.68  ? 331 ARG D NE  1 
ATOM   12935 C  CZ  . ARG D 1 331 ? -45.345 16.518  -30.515 1.00 43.72  ? 331 ARG D CZ  1 
ATOM   12936 N  NH1 . ARG D 1 331 ? -46.234 15.883  -29.765 1.00 55.13  ? 331 ARG D NH1 1 
ATOM   12937 N  NH2 . ARG D 1 331 ? -44.048 16.390  -30.243 1.00 40.54  ? 331 ARG D NH2 1 
ATOM   12938 N  N   . PRO D 1 332 ? -45.983 18.677  -37.371 1.00 44.88  ? 332 PRO D N   1 
ATOM   12939 C  CA  . PRO D 1 332 ? -45.286 19.146  -38.565 1.00 45.63  ? 332 PRO D CA  1 
ATOM   12940 C  C   . PRO D 1 332 ? -44.210 20.168  -38.251 1.00 54.63  ? 332 PRO D C   1 
ATOM   12941 O  O   . PRO D 1 332 ? -44.300 20.951  -37.303 1.00 56.70  ? 332 PRO D O   1 
ATOM   12942 C  CB  . PRO D 1 332 ? -46.412 19.800  -39.377 1.00 52.10  ? 332 PRO D CB  1 
ATOM   12943 C  CG  . PRO D 1 332 ? -47.402 20.282  -38.337 1.00 45.53  ? 332 PRO D CG  1 
ATOM   12944 C  CD  . PRO D 1 332 ? -47.076 19.598  -37.015 1.00 50.12  ? 332 PRO D CD  1 
ATOM   12945 N  N   . ILE D 1 333 ? -43.180 20.156  -39.080 1.00 52.74  ? 333 ILE D N   1 
ATOM   12946 C  CA  . ILE D 1 333 ? -42.217 21.254  -39.026 1.00 49.78  ? 333 ILE D CA  1 
ATOM   12947 C  C   . ILE D 1 333 ? -42.885 22.502  -39.581 1.00 48.91  ? 333 ILE D C   1 
ATOM   12948 O  O   . ILE D 1 333 ? -43.546 22.425  -40.627 1.00 46.94  ? 333 ILE D O   1 
ATOM   12949 C  CB  . ILE D 1 333 ? -40.965 20.898  -39.822 1.00 49.97  ? 333 ILE D CB  1 
ATOM   12950 C  CG1 . ILE D 1 333 ? -40.336 19.623  -39.251 1.00 47.39  ? 333 ILE D CG1 1 
ATOM   12951 C  CG2 . ILE D 1 333 ? -39.981 22.063  -39.796 1.00 46.10  ? 333 ILE D CG2 1 
ATOM   12952 C  CD1 . ILE D 1 333 ? -39.716 18.698  -40.294 1.00 47.13  ? 333 ILE D CD1 1 
ATOM   12953 N  N   . PRO D 1 334 ? -42.795 23.649  -38.916 1.00 56.60  ? 334 PRO D N   1 
ATOM   12954 C  CA  . PRO D 1 334 ? -43.289 24.886  -39.529 1.00 54.82  ? 334 PRO D CA  1 
ATOM   12955 C  C   . PRO D 1 334 ? -42.655 25.113  -40.898 1.00 56.18  ? 334 PRO D C   1 
ATOM   12956 O  O   . PRO D 1 334 ? -41.553 24.641  -41.186 1.00 52.67  ? 334 PRO D O   1 
ATOM   12957 C  CB  . PRO D 1 334 ? -42.874 25.967  -38.526 1.00 50.99  ? 334 PRO D CB  1 
ATOM   12958 C  CG  . PRO D 1 334 ? -42.845 25.255  -37.214 1.00 45.59  ? 334 PRO D CG  1 
ATOM   12959 C  CD  . PRO D 1 334 ? -42.388 23.848  -37.513 1.00 55.74  ? 334 PRO D CD  1 
ATOM   12960 N  N   . LEU D 1 335 ? -43.387 25.804  -41.766 1.00 59.24  ? 335 LEU D N   1 
ATOM   12961 C  CA  . LEU D 1 335 ? -42.795 26.273  -43.010 1.00 59.96  ? 335 LEU D CA  1 
ATOM   12962 C  C   . LEU D 1 335 ? -41.856 27.432  -42.721 1.00 62.10  ? 335 LEU D C   1 
ATOM   12963 O  O   . LEU D 1 335 ? -42.192 28.343  -41.959 1.00 57.35  ? 335 LEU D O   1 
ATOM   12964 C  CB  . LEU D 1 335 ? -43.872 26.722  -43.998 1.00 64.49  ? 335 LEU D CB  1 
ATOM   12965 C  CG  . LEU D 1 335 ? -44.736 25.690  -44.721 1.00 63.00  ? 335 LEU D CG  1 
ATOM   12966 C  CD1 . LEU D 1 335 ? -46.185 25.787  -44.275 1.00 61.47  ? 335 LEU D CD1 1 
ATOM   12967 C  CD2 . LEU D 1 335 ? -44.616 25.919  -46.217 1.00 58.07  ? 335 LEU D CD2 1 
ATOM   12968 N  N   . LYS D 1 336 ? -40.675 27.396  -43.332 1.00 64.66  ? 336 LYS D N   1 
ATOM   12969 C  CA  . LYS D 1 336 ? -39.761 28.518  -43.203 1.00 65.67  ? 336 LYS D CA  1 
ATOM   12970 C  C   . LYS D 1 336 ? -40.451 29.785  -43.705 1.00 70.32  ? 336 LYS D C   1 
ATOM   12971 O  O   . LYS D 1 336 ? -41.340 29.715  -44.560 1.00 70.25  ? 336 LYS D O   1 
ATOM   12972 C  CB  . LYS D 1 336 ? -38.477 28.254  -43.987 1.00 67.00  ? 336 LYS D CB  1 
ATOM   12973 C  CG  . LYS D 1 336 ? -38.076 26.784  -44.005 1.00 69.14  ? 336 LYS D CG  1 
ATOM   12974 C  CD  . LYS D 1 336 ? -36.806 26.534  -44.803 1.00 70.13  ? 336 LYS D CD  1 
ATOM   12975 C  CE  . LYS D 1 336 ? -36.154 25.224  -44.375 1.00 66.33  ? 336 LYS D CE  1 
ATOM   12976 N  NZ  . LYS D 1 336 ? -34.718 25.149  -44.762 1.00 71.91  ? 336 LYS D NZ  1 
ATOM   12977 N  N   . PRO D 1 337 ? -40.110 30.953  -43.157 1.00 75.98  ? 337 PRO D N   1 
ATOM   12978 C  CA  . PRO D 1 337 ? -40.705 32.187  -43.681 1.00 69.57  ? 337 PRO D CA  1 
ATOM   12979 C  C   . PRO D 1 337 ? -40.324 32.355  -45.142 1.00 64.65  ? 337 PRO D C   1 
ATOM   12980 O  O   . PRO D 1 337 ? -39.202 32.048  -45.553 1.00 65.38  ? 337 PRO D O   1 
ATOM   12981 C  CB  . PRO D 1 337 ? -40.111 33.288  -42.792 1.00 69.70  ? 337 PRO D CB  1 
ATOM   12982 C  CG  . PRO D 1 337 ? -39.626 32.577  -41.561 1.00 68.20  ? 337 PRO D CG  1 
ATOM   12983 C  CD  . PRO D 1 337 ? -39.204 31.211  -42.022 1.00 70.84  ? 337 PRO D CD  1 
ATOM   12984 N  N   . GLY D 1 338 ? -41.292 32.791  -45.941 1.00 64.58  ? 338 GLY D N   1 
ATOM   12985 C  CA  . GLY D 1 338 ? -41.059 32.876  -47.366 1.00 63.89  ? 338 GLY D CA  1 
ATOM   12986 C  C   . GLY D 1 338 ? -40.922 31.550  -48.081 1.00 63.63  ? 338 GLY D C   1 
ATOM   12987 O  O   . GLY D 1 338 ? -40.442 31.521  -49.220 1.00 62.06  ? 338 GLY D O   1 
ATOM   12988 N  N   . GLU D 1 339 ? -41.314 30.448  -47.451 1.00 64.22  ? 339 GLU D N   1 
ATOM   12989 C  CA  . GLU D 1 339 ? -41.419 29.169  -48.137 1.00 62.63  ? 339 GLU D CA  1 
ATOM   12990 C  C   . GLU D 1 339 ? -42.794 29.067  -48.785 1.00 59.21  ? 339 GLU D C   1 
ATOM   12991 O  O   . GLU D 1 339 ? -43.787 29.555  -48.239 1.00 53.98  ? 339 GLU D O   1 
ATOM   12992 C  CB  . GLU D 1 339 ? -41.203 28.011  -47.161 1.00 63.47  ? 339 GLU D CB  1 
ATOM   12993 C  CG  . GLU D 1 339 ? -40.410 26.846  -47.721 1.00 64.03  ? 339 GLU D CG  1 
ATOM   12994 C  CD  . GLU D 1 339 ? -40.523 25.600  -46.854 1.00 67.19  ? 339 GLU D CD  1 
ATOM   12995 O  OE1 . GLU D 1 339 ? -41.087 25.695  -45.739 1.00 65.25  ? 339 GLU D OE1 1 
ATOM   12996 O  OE2 . GLU D 1 339 ? -40.061 24.524  -47.295 1.00 61.42  ? 339 GLU D OE2 1 
ATOM   12997 N  N   . LEU D 1 340 ? -42.846 28.448  -49.959 1.00 60.12  ? 340 LEU D N   1 
ATOM   12998 C  CA  . LEU D 1 340 ? -44.106 28.275  -50.675 1.00 58.46  ? 340 LEU D CA  1 
ATOM   12999 C  C   . LEU D 1 340 ? -44.723 26.932  -50.308 1.00 51.54  ? 340 LEU D C   1 
ATOM   13000 O  O   . LEU D 1 340 ? -44.065 25.895  -50.481 1.00 48.12  ? 340 LEU D O   1 
ATOM   13001 C  CB  . LEU D 1 340 ? -43.892 28.350  -52.180 1.00 56.21  ? 340 LEU D CB  1 
ATOM   13002 C  CG  . LEU D 1 340 ? -43.337 29.650  -52.763 1.00 53.64  ? 340 LEU D CG  1 
ATOM   13003 C  CD1 . LEU D 1 340 ? -41.835 29.541  -52.843 1.00 58.65  ? 340 LEU D CD1 1 
ATOM   13004 C  CD2 . LEU D 1 340 ? -43.920 29.910  -54.146 1.00 41.25  ? 340 LEU D CD2 1 
ATOM   13005 N  N   . PRO D 1 341 ? -45.963 26.902  -49.805 1.00 54.26  ? 341 PRO D N   1 
ATOM   13006 C  CA  . PRO D 1 341 ? -46.575 25.616  -49.412 1.00 57.09  ? 341 PRO D CA  1 
ATOM   13007 C  C   . PRO D 1 341 ? -46.601 24.586  -50.526 1.00 62.36  ? 341 PRO D C   1 
ATOM   13008 O  O   . PRO D 1 341 ? -46.511 23.382  -50.254 1.00 220.58 ? 341 PRO D O   1 
ATOM   13009 C  CB  . PRO D 1 341 ? -47.993 26.028  -48.988 1.00 46.15  ? 341 PRO D CB  1 
ATOM   13010 C  CG  . PRO D 1 341 ? -47.853 27.444  -48.537 1.00 54.87  ? 341 PRO D CG  1 
ATOM   13011 C  CD  . PRO D 1 341 ? -46.807 28.054  -49.443 1.00 48.92  ? 341 PRO D CD  1 
ATOM   13012 N  N   . GLY D 1 342 ? -46.710 25.030  -51.776 1.00 52.40  ? 342 GLY D N   1 
ATOM   13013 C  CA  . GLY D 1 342 ? -46.716 24.151  -52.922 1.00 44.75  ? 342 GLY D CA  1 
ATOM   13014 C  C   . GLY D 1 342 ? -45.370 23.619  -53.339 1.00 48.28  ? 342 GLY D C   1 
ATOM   13015 O  O   . GLY D 1 342 ? -45.315 22.766  -54.229 1.00 48.13  ? 342 GLY D O   1 
ATOM   13016 N  N   . GLN D 1 343 ? -44.282 24.086  -52.731 1.00 51.67  ? 343 GLN D N   1 
ATOM   13017 C  CA  . GLN D 1 343 ? -42.947 23.642  -53.117 1.00 51.85  ? 343 GLN D CA  1 
ATOM   13018 C  C   . GLN D 1 343 ? -42.281 22.757  -52.076 1.00 53.51  ? 343 GLN D C   1 
ATOM   13019 O  O   . GLN D 1 343 ? -41.193 22.229  -52.335 1.00 47.64  ? 343 GLN D O   1 
ATOM   13020 C  CB  . GLN D 1 343 ? -42.064 24.851  -53.415 1.00 48.86  ? 343 GLN D CB  1 
ATOM   13021 C  CG  . GLN D 1 343 ? -42.695 25.807  -54.406 1.00 51.52  ? 343 GLN D CG  1 
ATOM   13022 C  CD  . GLN D 1 343 ? -41.683 26.690  -55.092 1.00 47.73  ? 343 GLN D CD  1 
ATOM   13023 O  OE1 . GLN D 1 343 ? -40.778 27.228  -54.453 1.00 49.16  ? 343 GLN D OE1 1 
ATOM   13024 N  NE2 . GLN D 1 343 ? -41.823 26.836  -56.404 1.00 45.60  ? 343 GLN D NE2 1 
ATOM   13025 N  N   . ARG D 1 344 ? -42.914 22.562  -50.925 1.00 59.01  ? 344 ARG D N   1 
ATOM   13026 C  CA  . ARG D 1 344 ? -42.420 21.783  -49.801 1.00 58.03  ? 344 ARG D CA  1 
ATOM   13027 C  C   . ARG D 1 344 ? -43.006 20.384  -49.845 1.00 57.02  ? 344 ARG D C   1 
ATOM   13028 O  O   . ARG D 1 344 ? -44.209 20.234  -50.107 1.00 59.76  ? 344 ARG D O   1 
ATOM   13029 C  CB  . ARG D 1 344 ? -42.788 22.484  -48.496 1.00 60.40  ? 344 ARG D CB  1 
ATOM   13030 C  CG  . ARG D 1 344 ? -43.304 21.608  -47.385 1.00 63.79  ? 344 ARG D CG  1 
ATOM   13031 C  CD  . ARG D 1 344 ? -43.742 22.466  -46.200 1.00 57.95  ? 344 ARG D CD  1 
ATOM   13032 N  NE  . ARG D 1 344 ? -44.214 21.654  -45.087 1.00 59.69  ? 344 ARG D NE  1 
ATOM   13033 C  CZ  . ARG D 1 344 ? -43.573 21.522  -43.934 1.00 61.52  ? 344 ARG D CZ  1 
ATOM   13034 N  NH1 . ARG D 1 344 ? -42.448 22.179  -43.688 1.00 61.82  ? 344 ARG D NH1 1 
ATOM   13035 N  NH2 . ARG D 1 344 ? -44.071 20.707  -43.008 1.00 58.31  ? 344 ARG D NH2 1 
ATOM   13036 N  N   . PRO D 1 345 ? -42.203 19.345  -49.635 1.00 58.22  ? 345 PRO D N   1 
ATOM   13037 C  CA  . PRO D 1 345 ? -42.698 17.969  -49.780 1.00 56.61  ? 345 PRO D CA  1 
ATOM   13038 C  C   . PRO D 1 345 ? -43.528 17.532  -48.578 1.00 57.22  ? 345 PRO D C   1 
ATOM   13039 O  O   . PRO D 1 345 ? -43.512 18.149  -47.512 1.00 57.02  ? 345 PRO D O   1 
ATOM   13040 C  CB  . PRO D 1 345 ? -41.418 17.135  -49.910 1.00 57.10  ? 345 PRO D CB  1 
ATOM   13041 C  CG  . PRO D 1 345 ? -40.302 18.134  -50.116 1.00 56.36  ? 345 PRO D CG  1 
ATOM   13042 C  CD  . PRO D 1 345 ? -40.747 19.389  -49.447 1.00 56.80  ? 345 PRO D CD  1 
ATOM   13043 N  N   . ALA D 1 346 ? -44.258 16.428  -48.772 1.00 61.25  ? 346 ALA D N   1 
ATOM   13044 C  CA  . ALA D 1 346 ? -45.340 16.066  -47.857 1.00 58.25  ? 346 ALA D CA  1 
ATOM   13045 C  C   . ALA D 1 346 ? -44.833 15.503  -46.538 1.00 56.97  ? 346 ALA D C   1 
ATOM   13046 O  O   . ALA D 1 346 ? -45.360 15.854  -45.476 1.00 57.51  ? 346 ALA D O   1 
ATOM   13047 C  CB  . ALA D 1 346 ? -46.277 15.055  -48.515 1.00 62.09  ? 346 ALA D CB  1 
ATOM   13048 N  N   . PHE D 1 347 ? -43.826 14.624  -46.583 1.00 62.78  ? 347 PHE D N   1 
ATOM   13049 C  CA  . PHE D 1 347 ? -43.328 13.970  -45.373 1.00 58.98  ? 347 PHE D CA  1 
ATOM   13050 C  C   . PHE D 1 347 ? -42.738 14.947  -44.370 1.00 56.58  ? 347 PHE D C   1 
ATOM   13051 O  O   . PHE D 1 347 ? -42.360 14.527  -43.271 1.00 58.97  ? 347 PHE D O   1 
ATOM   13052 C  CB  . PHE D 1 347 ? -42.257 12.921  -45.696 1.00 57.51  ? 347 PHE D CB  1 
ATOM   13053 C  CG  . PHE D 1 347 ? -41.188 13.396  -46.646 1.00 61.68  ? 347 PHE D CG  1 
ATOM   13054 C  CD1 . PHE D 1 347 ? -41.459 13.581  -47.996 1.00 61.06  ? 347 PHE D CD1 1 
ATOM   13055 C  CD2 . PHE D 1 347 ? -39.909 13.677  -46.177 1.00 58.16  ? 347 PHE D CD2 1 
ATOM   13056 C  CE1 . PHE D 1 347 ? -40.473 14.016  -48.858 1.00 64.67  ? 347 PHE D CE1 1 
ATOM   13057 C  CE2 . PHE D 1 347 ? -38.921 14.117  -47.035 1.00 59.49  ? 347 PHE D CE2 1 
ATOM   13058 C  CZ  . PHE D 1 347 ? -39.202 14.287  -48.376 1.00 63.83  ? 347 PHE D CZ  1 
ATOM   13059 N  N   . LEU D 1 348 ? -42.623 16.222  -44.723 1.00 56.15  ? 348 LEU D N   1 
ATOM   13060 C  CA  . LEU D 1 348 ? -42.227 17.239  -43.764 1.00 55.40  ? 348 LEU D CA  1 
ATOM   13061 C  C   . LEU D 1 348 ? -43.305 17.500  -42.716 1.00 57.15  ? 348 LEU D C   1 
ATOM   13062 O  O   . LEU D 1 348 ? -43.090 18.312  -41.808 1.00 57.60  ? 348 LEU D O   1 
ATOM   13063 C  CB  . LEU D 1 348 ? -41.872 18.526  -44.511 1.00 59.60  ? 348 LEU D CB  1 
ATOM   13064 C  CG  . LEU D 1 348 ? -40.570 18.518  -45.313 1.00 51.16  ? 348 LEU D CG  1 
ATOM   13065 C  CD1 . LEU D 1 348 ? -40.238 19.927  -45.787 1.00 54.71  ? 348 LEU D CD1 1 
ATOM   13066 C  CD2 . LEU D 1 348 ? -39.435 17.952  -44.459 1.00 44.78  ? 348 LEU D CD2 1 
ATOM   13067 N  N   . ASP D 1 349 ? -44.450 16.827  -42.808 1.00 58.36  ? 349 ASP D N   1 
ATOM   13068 C  CA  . ASP D 1 349 ? -45.484 16.919  -41.784 1.00 61.30  ? 349 ASP D CA  1 
ATOM   13069 C  C   . ASP D 1 349 ? -45.447 15.768  -40.790 1.00 52.18  ? 349 ASP D C   1 
ATOM   13070 O  O   . ASP D 1 349 ? -45.905 15.932  -39.649 1.00 49.29  ? 349 ASP D O   1 
ATOM   13071 C  CB  . ASP D 1 349 ? -46.863 16.986  -42.443 1.00 59.75  ? 349 ASP D CB  1 
ATOM   13072 C  CG  . ASP D 1 349 ? -46.991 18.174  -43.360 1.00 60.73  ? 349 ASP D CG  1 
ATOM   13073 O  OD1 . ASP D 1 349 ? -46.792 19.307  -42.870 1.00 61.07  ? 349 ASP D OD1 1 
ATOM   13074 O  OD2 . ASP D 1 349 ? -47.235 17.969  -44.569 1.00 60.84  ? 349 ASP D OD2 1 
ATOM   13075 N  N   . GLY D 1 350 ? -44.900 14.623  -41.193 1.00 53.00  ? 350 GLY D N   1 
ATOM   13076 C  CA  . GLY D 1 350 ? -44.730 13.491  -40.303 1.00 52.40  ? 350 GLY D CA  1 
ATOM   13077 C  C   . GLY D 1 350 ? -45.481 12.253  -40.746 1.00 52.55  ? 350 GLY D C   1 
ATOM   13078 O  O   . GLY D 1 350 ? -46.713 12.258  -40.810 1.00 56.00  ? 350 GLY D O   1 
ATOM   13079 N  N   . ILE D 1 351 ? -44.748 11.175  -41.049 1.00 48.18  ? 351 ILE D N   1 
ATOM   13080 C  CA  . ILE D 1 351 ? -45.378 9.933   -41.490 1.00 50.50  ? 351 ILE D CA  1 
ATOM   13081 C  C   . ILE D 1 351 ? -45.884 9.087   -40.332 1.00 49.93  ? 351 ILE D C   1 
ATOM   13082 O  O   . ILE D 1 351 ? -46.430 8.003   -40.573 1.00 48.97  ? 351 ILE D O   1 
ATOM   13083 C  CB  . ILE D 1 351 ? -44.397 9.144   -42.381 1.00 48.83  ? 351 ILE D CB  1 
ATOM   13084 C  CG1 . ILE D 1 351 ? -43.156 8.705   -41.593 1.00 51.05  ? 351 ILE D CG1 1 
ATOM   13085 C  CG2 . ILE D 1 351 ? -43.991 9.989   -43.557 1.00 42.00  ? 351 ILE D CG2 1 
ATOM   13086 C  CD1 . ILE D 1 351 ? -42.347 7.604   -42.278 1.00 45.17  ? 351 ILE D CD1 1 
ATOM   13087 N  N   . HIS D 1 352 ? -45.691 9.545   -39.089 1.00 51.80  ? 352 HIS D N   1 
ATOM   13088 C  CA  . HIS D 1 352 ? -46.366 9.051   -37.877 1.00 53.76  ? 352 HIS D CA  1 
ATOM   13089 C  C   . HIS D 1 352 ? -46.411 7.526   -37.778 1.00 52.68  ? 352 HIS D C   1 
ATOM   13090 O  O   . HIS D 1 352 ? -47.470 6.924   -37.582 1.00 51.54  ? 352 HIS D O   1 
ATOM   13091 C  CB  . HIS D 1 352 ? -47.776 9.658   -37.759 1.00 57.47  ? 352 HIS D CB  1 
ATOM   13092 C  CG  . HIS D 1 352 ? -48.723 9.262   -38.857 1.00 59.05  ? 352 HIS D CG  1 
ATOM   13093 N  ND1 . HIS D 1 352 ? -49.144 7.962   -39.055 1.00 61.20  ? 352 HIS D ND1 1 
ATOM   13094 C  CD2 . HIS D 1 352 ? -49.336 10.002  -39.814 1.00 57.83  ? 352 HIS D CD2 1 
ATOM   13095 C  CE1 . HIS D 1 352 ? -49.972 7.919   -40.085 1.00 57.22  ? 352 HIS D CE1 1 
ATOM   13096 N  NE2 . HIS D 1 352 ? -50.104 9.143   -40.565 1.00 51.14  ? 352 HIS D NE2 1 
ATOM   13097 N  N   . VAL D 1 353 ? -45.241 6.890   -37.874 1.00 47.61  ? 353 VAL D N   1 
ATOM   13098 C  CA  . VAL D 1 353 ? -45.186 5.456   -37.619 1.00 48.39  ? 353 VAL D CA  1 
ATOM   13099 C  C   . VAL D 1 353 ? -45.515 5.214   -36.153 1.00 47.63  ? 353 VAL D C   1 
ATOM   13100 O  O   . VAL D 1 353 ? -45.208 6.042   -35.282 1.00 47.44  ? 353 VAL D O   1 
ATOM   13101 C  CB  . VAL D 1 353 ? -43.815 4.865   -38.006 1.00 49.28  ? 353 VAL D CB  1 
ATOM   13102 C  CG1 . VAL D 1 353 ? -43.684 3.412   -37.556 1.00 47.15  ? 353 VAL D CG1 1 
ATOM   13103 C  CG2 . VAL D 1 353 ? -43.603 4.944   -39.502 1.00 47.25  ? 353 VAL D CG2 1 
ATOM   13104 N  N   . ASP D 1 354 ? -46.196 4.104   -35.881 1.00 50.25  ? 354 ASP D N   1 
ATOM   13105 C  CA  . ASP D 1 354 ? -46.562 3.721   -34.519 1.00 51.00  ? 354 ASP D CA  1 
ATOM   13106 C  C   . ASP D 1 354 ? -45.349 3.136   -33.806 1.00 42.88  ? 354 ASP D C   1 
ATOM   13107 O  O   . ASP D 1 354 ? -44.682 2.254   -34.356 1.00 48.78  ? 354 ASP D O   1 
ATOM   13108 C  CB  . ASP D 1 354 ? -47.716 2.706   -34.545 1.00 52.60  ? 354 ASP D CB  1 
ATOM   13109 C  CG  . ASP D 1 354 ? -48.166 2.276   -33.155 1.00 55.84  ? 354 ASP D CG  1 
ATOM   13110 O  OD1 . ASP D 1 354 ? -47.425 1.515   -32.493 1.00 54.74  ? 354 ASP D OD1 1 
ATOM   13111 O  OD2 . ASP D 1 354 ? -49.266 2.690   -32.727 1.00 55.20  ? 354 ASP D OD2 1 
ATOM   13112 N  N   . PRO D 1 355 ? -45.040 3.588   -32.588 1.00 44.97  ? 355 PRO D N   1 
ATOM   13113 C  CA  . PRO D 1 355 ? -43.836 3.087   -31.903 1.00 41.42  ? 355 PRO D CA  1 
ATOM   13114 C  C   . PRO D 1 355 ? -43.812 1.582   -31.673 1.00 50.00  ? 355 PRO D C   1 
ATOM   13115 O  O   . PRO D 1 355 ? -42.717 1.017   -31.559 1.00 48.82  ? 355 PRO D O   1 
ATOM   13116 C  CB  . PRO D 1 355 ? -43.848 3.860   -30.581 1.00 42.19  ? 355 PRO D CB  1 
ATOM   13117 C  CG  . PRO D 1 355 ? -44.599 5.106   -30.884 1.00 43.59  ? 355 PRO D CG  1 
ATOM   13118 C  CD  . PRO D 1 355 ? -45.660 4.715   -31.871 1.00 43.93  ? 355 PRO D CD  1 
ATOM   13119 N  N   . ASN D 1 356 ? -44.969 0.906   -31.591 1.00 54.31  ? 356 ASN D N   1 
ATOM   13120 C  CA  . ASN D 1 356 ? -44.973 -0.554  -31.450 1.00 57.12  ? 356 ASN D CA  1 
ATOM   13121 C  C   . ASN D 1 356 ? -44.627 -1.277  -32.748 1.00 55.31  ? 356 ASN D C   1 
ATOM   13122 O  O   . ASN D 1 356 ? -44.585 -2.513  -32.759 1.00 54.69  ? 356 ASN D O   1 
ATOM   13123 C  CB  . ASN D 1 356 ? -46.326 -1.079  -30.924 1.00 56.33  ? 356 ASN D CB  1 
ATOM   13124 C  CG  . ASN D 1 356 ? -46.999 -0.124  -29.937 1.00 63.62  ? 356 ASN D CG  1 
ATOM   13125 O  OD1 . ASN D 1 356 ? -46.523 0.072   -28.811 1.00 61.44  ? 356 ASN D OD1 1 
ATOM   13126 N  ND2 . ASN D 1 356 ? -48.108 0.483   -30.363 1.00 63.82  ? 356 ASN D ND2 1 
ATOM   13127 N  N   . ASP D 1 357 ? -44.375 -0.553  -33.841 1.00 55.64  ? 357 ASP D N   1 
ATOM   13128 C  CA  . ASP D 1 357 ? -43.890 -1.230  -35.035 1.00 52.93  ? 357 ASP D CA  1 
ATOM   13129 C  C   . ASP D 1 357 ? -42.517 -1.844  -34.820 1.00 49.54  ? 357 ASP D C   1 
ATOM   13130 O  O   . ASP D 1 357 ? -42.165 -2.800  -35.515 1.00 48.90  ? 357 ASP D O   1 
ATOM   13131 C  CB  . ASP D 1 357 ? -43.849 -0.267  -36.218 1.00 57.46  ? 357 ASP D CB  1 
ATOM   13132 C  CG  . ASP D 1 357 ? -45.225 0.007   -36.798 1.00 62.63  ? 357 ASP D CG  1 
ATOM   13133 O  OD1 . ASP D 1 357 ? -46.013 0.740   -36.161 1.00 58.47  ? 357 ASP D OD1 1 
ATOM   13134 O  OD2 . ASP D 1 357 ? -45.521 -0.532  -37.891 1.00 64.91  ? 357 ASP D OD2 1 
ATOM   13135 N  N   . VAL D 1 358 ? -41.753 -1.340  -33.848 1.00 55.78  ? 358 VAL D N   1 
ATOM   13136 C  CA  . VAL D 1 358 ? -40.388 -1.821  -33.646 1.00 52.58  ? 358 VAL D CA  1 
ATOM   13137 C  C   . VAL D 1 358 ? -40.352 -3.295  -33.255 1.00 56.52  ? 358 VAL D C   1 
ATOM   13138 O  O   . VAL D 1 358 ? -39.392 -3.996  -33.590 1.00 55.93  ? 358 VAL D O   1 
ATOM   13139 C  CB  . VAL D 1 358 ? -39.664 -0.938  -32.610 1.00 53.92  ? 358 VAL D CB  1 
ATOM   13140 C  CG1 . VAL D 1 358 ? -39.681 0.517   -33.067 1.00 50.88  ? 358 VAL D CG1 1 
ATOM   13141 C  CG2 . VAL D 1 358 ? -40.303 -1.064  -31.236 1.00 46.51  ? 358 VAL D CG2 1 
ATOM   13142 N  N   . PHE D 1 359 ? -41.395 -3.799  -32.576 1.00 55.67  ? 359 PHE D N   1 
ATOM   13143 C  CA  . PHE D 1 359 ? -41.342 -5.150  -32.009 1.00 55.63  ? 359 PHE D CA  1 
ATOM   13144 C  C   . PHE D 1 359 ? -41.036 -6.192  -33.078 1.00 57.73  ? 359 PHE D C   1 
ATOM   13145 O  O   . PHE D 1 359 ? -40.203 -7.089  -32.879 1.00 50.15  ? 359 PHE D O   1 
ATOM   13146 C  CB  . PHE D 1 359 ? -42.664 -5.479  -31.306 1.00 56.17  ? 359 PHE D CB  1 
ATOM   13147 C  CG  . PHE D 1 359 ? -42.887 -4.696  -30.037 1.00 56.69  ? 359 PHE D CG  1 
ATOM   13148 C  CD1 . PHE D 1 359 ? -42.260 -5.065  -28.856 1.00 52.86  ? 359 PHE D CD1 1 
ATOM   13149 C  CD2 . PHE D 1 359 ? -43.705 -3.573  -30.032 1.00 58.54  ? 359 PHE D CD2 1 
ATOM   13150 C  CE1 . PHE D 1 359 ? -42.457 -4.329  -27.690 1.00 54.36  ? 359 PHE D CE1 1 
ATOM   13151 C  CE2 . PHE D 1 359 ? -43.906 -2.836  -28.878 1.00 54.20  ? 359 PHE D CE2 1 
ATOM   13152 C  CZ  . PHE D 1 359 ? -43.281 -3.213  -27.704 1.00 53.99  ? 359 PHE D CZ  1 
ATOM   13153 N  N   . ASP D 1 360 ? -41.683 -6.072  -34.230 1.00 55.54  ? 360 ASP D N   1 
ATOM   13154 C  CA  . ASP D 1 360 ? -41.485 -7.038  -35.292 1.00 55.49  ? 360 ASP D CA  1 
ATOM   13155 C  C   . ASP D 1 360 ? -40.147 -6.861  -35.994 1.00 57.47  ? 360 ASP D C   1 
ATOM   13156 O  O   . ASP D 1 360 ? -39.716 -7.770  -36.712 1.00 54.74  ? 360 ASP D O   1 
ATOM   13157 C  CB  . ASP D 1 360 ? -42.649 -6.914  -36.268 1.00 61.83  ? 360 ASP D CB  1 
ATOM   13158 C  CG  . ASP D 1 360 ? -43.954 -6.580  -35.557 1.00 67.60  ? 360 ASP D CG  1 
ATOM   13159 O  OD1 . ASP D 1 360 ? -44.278 -7.246  -34.543 1.00 67.13  ? 360 ASP D OD1 1 
ATOM   13160 O  OD2 . ASP D 1 360 ? -44.638 -5.629  -35.988 1.00 67.92  ? 360 ASP D OD2 1 
ATOM   13161 N  N   . VAL D 1 361 ? -39.478 -5.726  -35.785 1.00 57.57  ? 361 VAL D N   1 
ATOM   13162 C  CA  . VAL D 1 361 ? -38.170 -5.468  -36.384 1.00 61.70  ? 361 VAL D CA  1 
ATOM   13163 C  C   . VAL D 1 361 ? -37.053 -5.398  -35.354 1.00 55.97  ? 361 VAL D C   1 
ATOM   13164 O  O   . VAL D 1 361 ? -35.876 -5.475  -35.742 1.00 52.36  ? 361 VAL D O   1 
ATOM   13165 C  CB  . VAL D 1 361 ? -38.178 -4.172  -37.230 1.00 47.64  ? 361 VAL D CB  1 
ATOM   13166 C  CG1 . VAL D 1 361 ? -39.235 -4.253  -38.304 1.00 51.16  ? 361 VAL D CG1 1 
ATOM   13167 C  CG2 . VAL D 1 361 ? -38.393 -2.952  -36.360 1.00 48.39  ? 361 VAL D CG2 1 
ATOM   13168 N  N   . ILE D 1 362 ? -37.379 -5.284  -34.062 1.00 58.80  ? 362 ILE D N   1 
ATOM   13169 C  CA  . ILE D 1 362 ? -36.413 -4.867  -33.048 1.00 52.50  ? 362 ILE D CA  1 
ATOM   13170 C  C   . ILE D 1 362 ? -35.240 -5.822  -32.933 1.00 51.36  ? 362 ILE D C   1 
ATOM   13171 O  O   . ILE D 1 362 ? -34.160 -5.419  -32.487 1.00 48.60  ? 362 ILE D O   1 
ATOM   13172 C  CB  . ILE D 1 362 ? -37.121 -4.698  -31.691 1.00 55.43  ? 362 ILE D CB  1 
ATOM   13173 C  CG1 . ILE D 1 362 ? -36.216 -3.964  -30.698 1.00 51.04  ? 362 ILE D CG1 1 
ATOM   13174 C  CG2 . ILE D 1 362 ? -37.593 -6.056  -31.156 1.00 57.18  ? 362 ILE D CG2 1 
ATOM   13175 C  CD1 . ILE D 1 362 ? -35.660 -2.668  -31.223 1.00 47.90  ? 362 ILE D CD1 1 
ATOM   13176 N  N   . GLU D 1 363 ? -35.410 -7.077  -33.348 1.00 50.74  ? 363 GLU D N   1 
ATOM   13177 C  CA  . GLU D 1 363 ? -34.299 -8.015  -33.302 1.00 54.20  ? 363 GLU D CA  1 
ATOM   13178 C  C   . GLU D 1 363 ? -33.143 -7.604  -34.214 1.00 54.64  ? 363 GLU D C   1 
ATOM   13179 O  O   . GLU D 1 363 ? -32.035 -8.136  -34.065 1.00 54.66  ? 363 GLU D O   1 
ATOM   13180 C  CB  . GLU D 1 363 ? -34.798 -9.412  -33.667 1.00 51.26  ? 363 GLU D CB  1 
ATOM   13181 C  CG  . GLU D 1 363 ? -34.142 -10.534 -32.873 1.00 60.52  ? 363 GLU D CG  1 
ATOM   13182 C  CD  . GLU D 1 363 ? -35.111 -11.666 -32.567 1.00 67.05  ? 363 GLU D CD  1 
ATOM   13183 O  OE1 . GLU D 1 363 ? -34.654 -12.806 -32.314 1.00 70.94  ? 363 GLU D OE1 1 
ATOM   13184 O  OE2 . GLU D 1 363 ? -36.334 -11.407 -32.560 1.00 69.60  ? 363 GLU D OE2 1 
ATOM   13185 N  N   . ASN D 1 364 ? -33.360 -6.668  -35.139 1.00 50.95  ? 364 ASN D N   1 
ATOM   13186 C  CA  . ASN D 1 364 ? -32.319 -6.265  -36.076 1.00 47.69  ? 364 ASN D CA  1 
ATOM   13187 C  C   . ASN D 1 364 ? -32.074 -4.766  -36.087 1.00 43.34  ? 364 ASN D C   1 
ATOM   13188 O  O   . ASN D 1 364 ? -31.363 -4.273  -36.971 1.00 45.24  ? 364 ASN D O   1 
ATOM   13189 C  CB  . ASN D 1 364 ? -32.672 -6.733  -37.481 1.00 47.62  ? 364 ASN D CB  1 
ATOM   13190 C  CG  . ASN D 1 364 ? -32.929 -8.205  -37.530 1.00 48.39  ? 364 ASN D CG  1 
ATOM   13191 O  OD1 . ASN D 1 364 ? -32.002 -9.004  -37.461 1.00 48.07  ? 364 ASN D OD1 1 
ATOM   13192 N  ND2 . ASN D 1 364 ? -34.197 -8.581  -37.622 1.00 51.08  ? 364 ASN D ND2 1 
ATOM   13193 N  N   . VAL D 1 365 ? -32.656 -4.028  -35.152 1.00 42.14  ? 365 VAL D N   1 
ATOM   13194 C  CA  . VAL D 1 365 ? -32.348 -2.615  -34.990 1.00 44.72  ? 365 VAL D CA  1 
ATOM   13195 C  C   . VAL D 1 365 ? -31.061 -2.527  -34.177 1.00 46.58  ? 365 VAL D C   1 
ATOM   13196 O  O   . VAL D 1 365 ? -31.062 -2.776  -32.968 1.00 48.09  ? 365 VAL D O   1 
ATOM   13197 C  CB  . VAL D 1 365 ? -33.497 -1.867  -34.314 1.00 41.44  ? 365 VAL D CB  1 
ATOM   13198 C  CG1 . VAL D 1 365 ? -33.072 -0.487  -33.932 1.00 41.79  ? 365 VAL D CG1 1 
ATOM   13199 C  CG2 . VAL D 1 365 ? -34.686 -1.805  -35.253 1.00 48.03  ? 365 VAL D CG2 1 
ATOM   13200 N  N   . VAL D 1 366 ? -29.950 -2.202  -34.846 1.00 38.92  ? 366 VAL D N   1 
ATOM   13201 C  CA  . VAL D 1 366 ? -28.649 -2.198  -34.185 1.00 33.77  ? 366 VAL D CA  1 
ATOM   13202 C  C   . VAL D 1 366 ? -28.215 -0.810  -33.715 1.00 36.90  ? 366 VAL D C   1 
ATOM   13203 O  O   . VAL D 1 366 ? -27.283 -0.705  -32.902 1.00 37.59  ? 366 VAL D O   1 
ATOM   13204 C  CB  . VAL D 1 366 ? -27.581 -2.789  -35.121 1.00 34.86  ? 366 VAL D CB  1 
ATOM   13205 C  CG1 . VAL D 1 366 ? -27.914 -4.226  -35.460 1.00 29.69  ? 366 VAL D CG1 1 
ATOM   13206 C  CG2 . VAL D 1 366 ? -27.463 -1.949  -36.387 1.00 33.53  ? 366 VAL D CG2 1 
ATOM   13207 N  N   . PHE D 1 367 ? -28.837 0.250   -34.216 1.00 36.35  ? 367 PHE D N   1 
ATOM   13208 C  CA  . PHE D 1 367 ? -28.382 1.613   -33.986 1.00 33.96  ? 367 PHE D CA  1 
ATOM   13209 C  C   . PHE D 1 367 ? -29.556 2.511   -34.298 1.00 28.26  ? 367 PHE D C   1 
ATOM   13210 O  O   . PHE D 1 367 ? -30.313 2.234   -35.219 1.00 30.36  ? 367 PHE D O   1 
ATOM   13211 C  CB  . PHE D 1 367 ? -27.169 1.969   -34.871 1.00 31.23  ? 367 PHE D CB  1 
ATOM   13212 C  CG  . PHE D 1 367 ? -26.513 3.287   -34.517 1.00 34.10  ? 367 PHE D CG  1 
ATOM   13213 C  CD1 . PHE D 1 367 ? -25.679 3.386   -33.417 1.00 34.63  ? 367 PHE D CD1 1 
ATOM   13214 C  CD2 . PHE D 1 367 ? -26.715 4.421   -35.306 1.00 32.43  ? 367 PHE D CD2 1 
ATOM   13215 C  CE1 . PHE D 1 367 ? -25.067 4.597   -33.084 1.00 35.83  ? 367 PHE D CE1 1 
ATOM   13216 C  CE2 . PHE D 1 367 ? -26.113 5.631   -34.988 1.00 38.77  ? 367 PHE D CE2 1 
ATOM   13217 C  CZ  . PHE D 1 367 ? -25.278 5.716   -33.873 1.00 38.49  ? 367 PHE D CZ  1 
ATOM   13218 N  N   . ILE D 1 368 ? -29.719 3.568   -33.520 1.00 33.94  ? 368 ILE D N   1 
ATOM   13219 C  CA  . ILE D 1 368 ? -30.824 4.485   -33.720 1.00 37.57  ? 368 ILE D CA  1 
ATOM   13220 C  C   . ILE D 1 368 ? -30.297 5.913   -33.708 1.00 36.29  ? 368 ILE D C   1 
ATOM   13221 O  O   . ILE D 1 368 ? -29.649 6.341   -32.743 1.00 32.09  ? 368 ILE D O   1 
ATOM   13222 C  CB  . ILE D 1 368 ? -31.927 4.298   -32.669 1.00 37.16  ? 368 ILE D CB  1 
ATOM   13223 C  CG1 . ILE D 1 368 ? -32.515 2.895   -32.787 1.00 41.05  ? 368 ILE D CG1 1 
ATOM   13224 C  CG2 . ILE D 1 368 ? -33.019 5.330   -32.870 1.00 39.92  ? 368 ILE D CG2 1 
ATOM   13225 C  CD1 . ILE D 1 368 ? -33.575 2.576   -31.740 1.00 39.72  ? 368 ILE D CD1 1 
ATOM   13226 N  N   . GLN D 1 369 ? -30.576 6.645   -34.784 1.00 31.45  ? 369 GLN D N   1 
ATOM   13227 C  CA  . GLN D 1 369 ? -30.335 8.077   -34.825 1.00 35.00  ? 369 GLN D CA  1 
ATOM   13228 C  C   . GLN D 1 369 ? -31.520 8.814   -34.213 1.00 36.47  ? 369 GLN D C   1 
ATOM   13229 O  O   . GLN D 1 369 ? -32.653 8.699   -34.694 1.00 40.13  ? 369 GLN D O   1 
ATOM   13230 C  CB  . GLN D 1 369 ? -30.093 8.530   -36.262 1.00 37.20  ? 369 GLN D CB  1 
ATOM   13231 C  CG  . GLN D 1 369 ? -28.788 8.009   -36.850 1.00 39.17  ? 369 GLN D CG  1 
ATOM   13232 C  CD  . GLN D 1 369 ? -28.746 8.165   -38.368 1.00 45.52  ? 369 GLN D CD  1 
ATOM   13233 O  OE1 . GLN D 1 369 ? -29.779 8.402   -38.993 1.00 44.07  ? 369 GLN D OE1 1 
ATOM   13234 N  NE2 . GLN D 1 369 ? -27.551 8.033   -38.964 1.00 36.81  ? 369 GLN D NE2 1 
ATOM   13235 N  N   . ALA D 1 370 ? -31.258 9.575   -33.154 1.00 36.12  ? 370 ALA D N   1 
ATOM   13236 C  CA  . ALA D 1 370 ? -32.290 10.360  -32.486 1.00 35.58  ? 370 ALA D CA  1 
ATOM   13237 C  C   . ALA D 1 370 ? -32.499 11.664  -33.249 1.00 32.43  ? 370 ALA D C   1 
ATOM   13238 O  O   . ALA D 1 370 ? -32.067 12.742  -32.841 1.00 35.60  ? 370 ALA D O   1 
ATOM   13239 C  CB  . ALA D 1 370 ? -31.911 10.615  -31.032 1.00 36.50  ? 370 ALA D CB  1 
ATOM   13240 N  N   . LYS D 1 371 ? -33.187 11.547  -34.382 1.00 40.05  ? 371 LYS D N   1 
ATOM   13241 C  CA  . LYS D 1 371 ? -33.520 12.720  -35.184 1.00 36.53  ? 371 LYS D CA  1 
ATOM   13242 C  C   . LYS D 1 371 ? -34.529 13.599  -34.456 1.00 32.90  ? 371 LYS D C   1 
ATOM   13243 O  O   . LYS D 1 371 ? -35.414 13.105  -33.750 1.00 42.45  ? 371 LYS D O   1 
ATOM   13244 C  CB  . LYS D 1 371 ? -34.081 12.293  -36.546 1.00 35.74  ? 371 LYS D CB  1 
ATOM   13245 C  CG  . LYS D 1 371 ? -34.392 13.466  -37.496 1.00 37.64  ? 371 LYS D CG  1 
ATOM   13246 C  CD  . LYS D 1 371 ? -33.296 13.705  -38.541 1.00 32.57  ? 371 LYS D CD  1 
ATOM   13247 C  CE  . LYS D 1 371 ? -33.741 13.176  -39.886 1.00 36.12  ? 371 LYS D CE  1 
ATOM   13248 N  NZ  . LYS D 1 371 ? -33.008 11.940  -40.225 1.00 40.05  ? 371 LYS D NZ  1 
ATOM   13249 N  N   . PHE D 1 372 ? -34.379 14.908  -34.614 1.00 33.84  ? 372 PHE D N   1 
ATOM   13250 C  CA  . PHE D 1 372 ? -35.293 15.879  -34.028 1.00 35.46  ? 372 PHE D CA  1 
ATOM   13251 C  C   . PHE D 1 372 ? -35.032 17.233  -34.676 1.00 35.77  ? 372 PHE D C   1 
ATOM   13252 O  O   . PHE D 1 372 ? -34.099 17.393  -35.466 1.00 35.28  ? 372 PHE D O   1 
ATOM   13253 C  CB  . PHE D 1 372 ? -35.144 15.945  -32.504 1.00 33.80  ? 372 PHE D CB  1 
ATOM   13254 C  CG  . PHE D 1 372 ? -33.936 16.711  -32.026 1.00 32.61  ? 372 PHE D CG  1 
ATOM   13255 C  CD1 . PHE D 1 372 ? -32.664 16.182  -32.151 1.00 30.44  ? 372 PHE D CD1 1 
ATOM   13256 C  CD2 . PHE D 1 372 ? -34.085 17.946  -31.401 1.00 31.72  ? 372 PHE D CD2 1 
ATOM   13257 C  CE1 . PHE D 1 372 ? -31.560 16.881  -31.688 1.00 30.04  ? 372 PHE D CE1 1 
ATOM   13258 C  CE2 . PHE D 1 372 ? -32.984 18.650  -30.940 1.00 28.14  ? 372 PHE D CE2 1 
ATOM   13259 C  CZ  . PHE D 1 372 ? -31.722 18.124  -31.089 1.00 27.47  ? 372 PHE D CZ  1 
ATOM   13260 N  N   . HIS D 1 373 ? -35.869 18.219  -34.332 1.00 33.28  ? 373 HIS D N   1 
ATOM   13261 C  CA  . HIS D 1 373 ? -35.834 19.490  -35.043 1.00 37.01  ? 373 HIS D CA  1 
ATOM   13262 C  C   . HIS D 1 373 ? -35.875 20.694  -34.114 1.00 34.97  ? 373 HIS D C   1 
ATOM   13263 O  O   . HIS D 1 373 ? -35.223 21.700  -34.392 1.00 29.06  ? 373 HIS D O   1 
ATOM   13264 C  CB  . HIS D 1 373 ? -36.988 19.569  -36.050 1.00 36.86  ? 373 HIS D CB  1 
ATOM   13265 C  CG  . HIS D 1 373 ? -37.061 18.391  -36.969 1.00 38.38  ? 373 HIS D CG  1 
ATOM   13266 N  ND1 . HIS D 1 373 ? -36.299 18.289  -38.115 1.00 43.08  ? 373 HIS D ND1 1 
ATOM   13267 C  CD2 . HIS D 1 373 ? -37.786 17.252  -36.899 1.00 40.80  ? 373 HIS D CD2 1 
ATOM   13268 C  CE1 . HIS D 1 373 ? -36.559 17.140  -38.713 1.00 38.43  ? 373 HIS D CE1 1 
ATOM   13269 N  NE2 . HIS D 1 373 ? -37.460 16.494  -37.997 1.00 35.48  ? 373 HIS D NE2 1 
ATOM   13270 N  N   . ASP D 1 374 ? -36.620 20.612  -33.014 1.00 36.43  ? 374 ASP D N   1 
ATOM   13271 C  CA  . ASP D 1 374 ? -36.854 21.798  -32.191 1.00 40.31  ? 374 ASP D CA  1 
ATOM   13272 C  C   . ASP D 1 374 ? -37.266 21.354  -30.794 1.00 42.19  ? 374 ASP D C   1 
ATOM   13273 O  O   . ASP D 1 374 ? -38.118 20.471  -30.662 1.00 41.83  ? 374 ASP D O   1 
ATOM   13274 C  CB  . ASP D 1 374 ? -37.932 22.677  -32.839 1.00 41.50  ? 374 ASP D CB  1 
ATOM   13275 C  CG  . ASP D 1 374 ? -38.078 24.020  -32.177 1.00 41.22  ? 374 ASP D CG  1 
ATOM   13276 O  OD1 . ASP D 1 374 ? -37.176 24.431  -31.417 1.00 43.49  ? 374 ASP D OD1 1 
ATOM   13277 O  OD2 . ASP D 1 374 ? -39.102 24.682  -32.446 1.00 42.63  ? 374 ASP D OD2 1 
ATOM   13278 N  N   . ILE D 1 375 ? -36.633 21.932  -29.763 1.00 40.36  ? 375 ILE D N   1 
ATOM   13279 C  CA  . ILE D 1 375 ? -36.973 21.687  -28.359 1.00 39.33  ? 375 ILE D CA  1 
ATOM   13280 C  C   . ILE D 1 375 ? -36.862 23.010  -27.616 1.00 38.55  ? 375 ILE D C   1 
ATOM   13281 O  O   . ILE D 1 375 ? -35.818 23.667  -27.676 1.00 38.78  ? 375 ILE D O   1 
ATOM   13282 C  CB  . ILE D 1 375 ? -36.057 20.626  -27.714 1.00 41.19  ? 375 ILE D CB  1 
ATOM   13283 C  CG1 . ILE D 1 375 ? -35.955 19.386  -28.608 1.00 34.95  ? 375 ILE D CG1 1 
ATOM   13284 C  CG2 . ILE D 1 375 ? -36.545 20.268  -26.307 1.00 37.03  ? 375 ILE D CG2 1 
ATOM   13285 C  CD1 . ILE D 1 375 ? -35.520 18.134  -27.906 1.00 38.47  ? 375 ILE D CD1 1 
ATOM   13286 N  N   . ASP D 1 376 ? -37.928 23.408  -26.911 1.00 43.07  ? 376 ASP D N   1 
ATOM   13287 C  CA  . ASP D 1 376 ? -37.986 24.775  -26.398 1.00 43.08  ? 376 ASP D CA  1 
ATOM   13288 C  C   . ASP D 1 376 ? -37.386 24.888  -24.993 1.00 37.08  ? 376 ASP D C   1 
ATOM   13289 O  O   . ASP D 1 376 ? -36.842 23.931  -24.441 1.00 35.77  ? 376 ASP D O   1 
ATOM   13290 C  CB  . ASP D 1 376 ? -39.422 25.308  -26.411 1.00 48.05  ? 376 ASP D CB  1 
ATOM   13291 C  CG  . ASP D 1 376 ? -40.394 24.429  -25.646 1.00 44.83  ? 376 ASP D CG  1 
ATOM   13292 O  OD1 . ASP D 1 376 ? -39.962 23.631  -24.784 1.00 44.76  ? 376 ASP D OD1 1 
ATOM   13293 O  OD2 . ASP D 1 376 ? -41.610 24.559  -25.906 1.00 46.78  ? 376 ASP D OD2 1 
ATOM   13294 N  N   . GLU D 1 377 ? -37.488 26.092  -24.405 1.00 42.25  ? 377 GLU D N   1 
ATOM   13295 C  CA  . GLU D 1 377 ? -36.920 26.349  -23.082 1.00 41.38  ? 377 GLU D CA  1 
ATOM   13296 C  C   . GLU D 1 377 ? -37.519 25.454  -22.006 1.00 47.11  ? 377 GLU D C   1 
ATOM   13297 O  O   . GLU D 1 377 ? -36.934 25.329  -20.923 1.00 41.20  ? 377 GLU D O   1 
ATOM   13298 C  CB  . GLU D 1 377 ? -37.117 27.815  -22.674 1.00 48.61  ? 377 GLU D CB  1 
ATOM   13299 C  CG  . GLU D 1 377 ? -36.421 28.830  -23.565 1.00 49.78  ? 377 GLU D CG  1 
ATOM   13300 C  CD  . GLU D 1 377 ? -37.132 29.024  -24.894 1.00 56.78  ? 377 GLU D CD  1 
ATOM   13301 O  OE1 . GLU D 1 377 ? -38.333 29.377  -24.887 1.00 57.54  ? 377 GLU D OE1 1 
ATOM   13302 O  OE2 . GLU D 1 377 ? -36.497 28.791  -25.946 1.00 56.97  ? 377 GLU D OE2 1 
ATOM   13303 N  N   . GLU D 1 378 ? -38.678 24.847  -22.277 1.00 49.00  ? 378 GLU D N   1 
ATOM   13304 C  CA  . GLU D 1 378 ? -39.367 23.964  -21.349 1.00 48.07  ? 378 GLU D CA  1 
ATOM   13305 C  C   . GLU D 1 378 ? -39.186 22.502  -21.698 1.00 43.45  ? 378 GLU D C   1 
ATOM   13306 O  O   . GLU D 1 378 ? -39.875 21.659  -21.117 1.00 43.28  ? 378 GLU D O   1 
ATOM   13307 C  CB  . GLU D 1 378 ? -40.869 24.271  -21.320 1.00 52.13  ? 378 GLU D CB  1 
ATOM   13308 C  CG  . GLU D 1 378 ? -41.250 25.738  -21.309 1.00 49.08  ? 378 GLU D CG  1 
ATOM   13309 C  CD  . GLU D 1 378 ? -40.985 26.402  -19.979 1.00 57.30  ? 378 GLU D CD  1 
ATOM   13310 O  OE1 . GLU D 1 378 ? -40.640 25.675  -19.018 1.00 49.73  ? 378 GLU D OE1 1 
ATOM   13311 O  OE2 . GLU D 1 378 ? -41.125 27.648  -19.902 1.00 54.83  ? 378 GLU D OE2 1 
ATOM   13312 N  N   . LEU D 1 379 ? -38.310 22.186  -22.656 1.00 42.99  ? 379 LEU D N   1 
ATOM   13313 C  CA  . LEU D 1 379 ? -38.005 20.796  -23.031 1.00 40.49  ? 379 LEU D CA  1 
ATOM   13314 C  C   . LEU D 1 379 ? -39.211 20.086  -23.644 1.00 41.37  ? 379 LEU D C   1 
ATOM   13315 O  O   . LEU D 1 379 ? -39.467 18.910  -23.372 1.00 43.34  ? 379 LEU D O   1 
ATOM   13316 C  CB  . LEU D 1 379 ? -37.483 19.986  -21.843 1.00 41.87  ? 379 LEU D CB  1 
ATOM   13317 C  CG  . LEU D 1 379 ? -36.146 20.296  -21.205 1.00 33.42  ? 379 LEU D CG  1 
ATOM   13318 C  CD1 . LEU D 1 379 ? -35.668 19.004  -20.569 1.00 33.80  ? 379 LEU D CD1 1 
ATOM   13319 C  CD2 . LEU D 1 379 ? -35.161 20.809  -22.275 1.00 38.71  ? 379 LEU D CD2 1 
ATOM   13320 N  N   . ASP D 1 380 ? -39.957 20.805  -24.476 1.00 47.25  ? 380 ASP D N   1 
ATOM   13321 C  CA  . ASP D 1 380 ? -41.080 20.248  -25.228 1.00 45.05  ? 380 ASP D CA  1 
ATOM   13322 C  C   . ASP D 1 380 ? -40.624 20.072  -26.676 1.00 39.59  ? 380 ASP D C   1 
ATOM   13323 O  O   . ASP D 1 380 ? -40.296 21.050  -27.355 1.00 43.70  ? 380 ASP D O   1 
ATOM   13324 C  CB  . ASP D 1 380 ? -42.295 21.170  -25.115 1.00 45.72  ? 380 ASP D CB  1 
ATOM   13325 C  CG  . ASP D 1 380 ? -43.489 20.666  -25.893 1.00 51.02  ? 380 ASP D CG  1 
ATOM   13326 O  OD1 . ASP D 1 380 ? -44.073 21.459  -26.661 1.00 49.19  ? 380 ASP D OD1 1 
ATOM   13327 O  OD2 . ASP D 1 380 ? -43.849 19.478  -25.729 1.00 56.21  ? 380 ASP D OD2 1 
ATOM   13328 N  N   . ASP D 1 381 ? -40.498 18.837  -27.117 1.00 43.58  ? 381 ASP D N   1 
ATOM   13329 C  CA  . ASP D 1 381 ? -40.142 18.612  -28.534 1.00 40.51  ? 381 ASP D CA  1 
ATOM   13330 C  C   . ASP D 1 381 ? -41.317 19.114  -29.361 1.00 46.62  ? 381 ASP D C   1 
ATOM   13331 O  O   . ASP D 1 381 ? -42.449 18.745  -29.043 1.00 52.81  ? 381 ASP D O   1 
ATOM   13332 C  CB  . ASP D 1 381 ? -39.838 17.144  -28.809 1.00 44.23  ? 381 ASP D CB  1 
ATOM   13333 C  CG  . ASP D 1 381 ? -39.260 16.881  -30.187 1.00 44.90  ? 381 ASP D CG  1 
ATOM   13334 O  OD1 . ASP D 1 381 ? -39.939 17.191  -31.177 1.00 39.78  ? 381 ASP D OD1 1 
ATOM   13335 O  OD2 . ASP D 1 381 ? -38.137 16.363  -30.255 1.00 43.52  ? 381 ASP D OD2 1 
ATOM   13336 N  N   . LYS D 1 382 ? -41.057 19.899  -30.395 1.00 47.13  ? 382 LYS D N   1 
ATOM   13337 C  CA  . LYS D 1 382 ? -42.167 20.520  -31.158 1.00 43.60  ? 382 LYS D CA  1 
ATOM   13338 C  C   . LYS D 1 382 ? -42.613 19.611  -32.315 1.00 46.56  ? 382 LYS D C   1 
ATOM   13339 O  O   . LYS D 1 382 ? -43.493 20.060  -33.064 1.00 47.31  ? 382 LYS D O   1 
ATOM   13340 C  CB  . LYS D 1 382 ? -41.718 21.911  -31.612 1.00 40.82  ? 382 LYS D CB  1 
ATOM   13341 C  CG  . LYS D 1 382 ? -42.285 23.081  -30.821 1.00 43.99  ? 382 LYS D CG  1 
ATOM   13342 C  CD  . LYS D 1 382 ? -42.148 22.923  -29.328 1.00 41.74  ? 382 LYS D CD  1 
ATOM   13343 C  CE  . LYS D 1 382 ? -43.226 23.657  -28.564 1.00 45.26  ? 382 LYS D CE  1 
ATOM   13344 N  NZ  . LYS D 1 382 ? -42.745 24.961  -28.055 1.00 48.23  ? 382 LYS D NZ  1 
ATOM   13345 N  N   . GLN D 1 383 ? -42.064 18.393  -32.454 1.00 42.02  ? 383 GLN D N   1 
ATOM   13346 C  CA  . GLN D 1 383 ? -42.400 17.538  -33.630 1.00 43.76  ? 383 GLN D CA  1 
ATOM   13347 C  C   . GLN D 1 383 ? -42.471 16.107  -33.086 1.00 43.79  ? 383 GLN D C   1 
ATOM   13348 O  O   . GLN D 1 383 ? -43.525 15.491  -33.261 1.00 45.26  ? 383 GLN D O   1 
ATOM   13349 C  CB  . GLN D 1 383 ? -41.447 17.814  -34.801 1.00 42.28  ? 383 GLN D CB  1 
ATOM   13350 C  CG  . GLN D 1 383 ? -41.760 19.073  -35.593 1.00 41.25  ? 383 GLN D CG  1 
ATOM   13351 C  CD  . GLN D 1 383 ? -41.024 20.268  -35.041 1.00 47.28  ? 383 GLN D CD  1 
ATOM   13352 O  OE1 . GLN D 1 383 ? -40.088 20.134  -34.258 1.00 45.03  ? 383 GLN D OE1 1 
ATOM   13353 N  NE2 . GLN D 1 383 ? -41.460 21.452  -35.431 1.00 44.90  ? 383 GLN D NE2 1 
ATOM   13354 N  N   . ILE D 1 384 ? -41.404 15.586  -32.483 1.00 41.31  ? 384 ILE D N   1 
ATOM   13355 C  CA  . ILE D 1 384 ? -41.286 14.131  -32.182 1.00 38.44  ? 384 ILE D CA  1 
ATOM   13356 C  C   . ILE D 1 384 ? -41.809 13.738  -30.799 1.00 41.11  ? 384 ILE D C   1 
ATOM   13357 O  O   . ILE D 1 384 ? -41.403 14.348  -29.812 1.00 45.52  ? 384 ILE D O   1 
ATOM   13358 C  CB  . ILE D 1 384 ? -39.803 13.757  -32.360 1.00 38.69  ? 384 ILE D CB  1 
ATOM   13359 C  CG1 . ILE D 1 384 ? -39.250 14.238  -33.703 1.00 45.28  ? 384 ILE D CG1 1 
ATOM   13360 C  CG2 . ILE D 1 384 ? -39.597 12.264  -32.173 1.00 42.21  ? 384 ILE D CG2 1 
ATOM   13361 C  CD1 . ILE D 1 384 ? -39.216 13.170  -34.765 1.00 42.23  ? 384 ILE D CD1 1 
ATOM   13362 N  N   . PRO D 1 385 ? -42.712 12.755  -30.697 1.00 43.36  ? 385 PRO D N   1 
ATOM   13363 C  CA  . PRO D 1 385 ? -43.164 12.269  -29.379 1.00 44.49  ? 385 PRO D CA  1 
ATOM   13364 C  C   . PRO D 1 385 ? -42.209 11.250  -28.771 1.00 39.53  ? 385 PRO D C   1 
ATOM   13365 O  O   . PRO D 1 385 ? -42.213 10.075  -29.142 1.00 40.46  ? 385 PRO D O   1 
ATOM   13366 C  CB  . PRO D 1 385 ? -44.530 11.645  -29.690 1.00 40.07  ? 385 PRO D CB  1 
ATOM   13367 C  CG  . PRO D 1 385 ? -44.390 11.160  -31.107 1.00 41.98  ? 385 PRO D CG  1 
ATOM   13368 C  CD  . PRO D 1 385 ? -43.454 12.135  -31.810 1.00 43.64  ? 385 PRO D CD  1 
ATOM   13369 N  N   . TRP D 1 386 ? -41.366 11.689  -27.845 1.00 44.05  ? 386 TRP D N   1 
ATOM   13370 C  CA  . TRP D 1 386 ? -40.338 10.789  -27.330 1.00 41.95  ? 386 TRP D CA  1 
ATOM   13371 C  C   . TRP D 1 386 ? -40.896 9.818   -26.292 1.00 41.18  ? 386 TRP D C   1 
ATOM   13372 O  O   . TRP D 1 386 ? -40.500 8.642   -26.259 1.00 41.05  ? 386 TRP D O   1 
ATOM   13373 C  CB  . TRP D 1 386 ? -39.180 11.615  -26.769 1.00 39.84  ? 386 TRP D CB  1 
ATOM   13374 C  CG  . TRP D 1 386 ? -38.369 12.233  -27.878 1.00 41.30  ? 386 TRP D CG  1 
ATOM   13375 C  CD1 . TRP D 1 386 ? -38.347 13.549  -28.253 1.00 37.30  ? 386 TRP D CD1 1 
ATOM   13376 C  CD2 . TRP D 1 386 ? -37.499 11.541  -28.787 1.00 37.07  ? 386 TRP D CD2 1 
ATOM   13377 N  NE1 . TRP D 1 386 ? -37.500 13.718  -29.326 1.00 40.57  ? 386 TRP D NE1 1 
ATOM   13378 C  CE2 . TRP D 1 386 ? -36.972 12.501  -29.673 1.00 38.77  ? 386 TRP D CE2 1 
ATOM   13379 C  CE3 . TRP D 1 386 ? -37.113 10.209  -28.932 1.00 35.33  ? 386 TRP D CE3 1 
ATOM   13380 C  CZ2 . TRP D 1 386 ? -36.078 12.166  -30.683 1.00 34.85  ? 386 TRP D CZ2 1 
ATOM   13381 C  CZ3 . TRP D 1 386 ? -36.224 9.881   -29.939 1.00 37.55  ? 386 TRP D CZ3 1 
ATOM   13382 C  CH2 . TRP D 1 386 ? -35.723 10.854  -30.804 1.00 33.78  ? 386 TRP D CH2 1 
ATOM   13383 N  N   . GLU D 1 387 ? -41.840 10.274  -25.470 1.00 43.03  ? 387 GLU D N   1 
ATOM   13384 C  CA  . GLU D 1 387 ? -42.400 9.407   -24.437 1.00 48.88  ? 387 GLU D CA  1 
ATOM   13385 C  C   . GLU D 1 387 ? -42.943 8.119   -25.070 1.00 38.83  ? 387 GLU D C   1 
ATOM   13386 O  O   . GLU D 1 387 ? -42.425 7.044   -24.748 1.00 42.03  ? 387 GLU D O   1 
ATOM   13387 C  CB  . GLU D 1 387 ? -43.447 10.164  -23.604 1.00 40.77  ? 387 GLU D CB  1 
ATOM   13388 C  CG  . GLU D 1 387 ? -43.347 9.950   -22.098 1.00 51.64  ? 387 GLU D CG  1 
ATOM   13389 C  CD  . GLU D 1 387 ? -43.884 8.598   -21.654 1.00 57.42  ? 387 GLU D CD  1 
ATOM   13390 O  OE1 . GLU D 1 387 ? -44.516 7.909   -22.480 1.00 55.93  ? 387 GLU D OE1 1 
ATOM   13391 O  OE2 . GLU D 1 387 ? -43.685 8.223   -20.475 1.00 60.03  ? 387 GLU D OE2 1 
ATOM   13392 N  N   . PRO D 1 388 ? -43.923 8.150   -25.993 1.00 40.56  ? 388 PRO D N   1 
ATOM   13393 C  CA  . PRO D 1 388 ? -44.319 6.882   -26.635 1.00 39.15  ? 388 PRO D CA  1 
ATOM   13394 C  C   . PRO D 1 388 ? -43.172 6.145   -27.313 1.00 39.75  ? 388 PRO D C   1 
ATOM   13395 O  O   . PRO D 1 388 ? -43.158 4.905   -27.302 1.00 39.37  ? 388 PRO D O   1 
ATOM   13396 C  CB  . PRO D 1 388 ? -45.397 7.304   -27.648 1.00 42.33  ? 388 PRO D CB  1 
ATOM   13397 C  CG  . PRO D 1 388 ? -45.477 8.771   -27.611 1.00 39.69  ? 388 PRO D CG  1 
ATOM   13398 C  CD  . PRO D 1 388 ? -44.851 9.239   -26.354 1.00 39.82  ? 388 PRO D CD  1 
ATOM   13399 N  N   . VAL D 1 389 ? -42.203 6.867   -27.888 1.00 40.96  ? 389 VAL D N   1 
ATOM   13400 C  CA  . VAL D 1 389 ? -41.138 6.226   -28.665 1.00 39.16  ? 389 VAL D CA  1 
ATOM   13401 C  C   . VAL D 1 389 ? -40.148 5.527   -27.744 1.00 37.75  ? 389 VAL D C   1 
ATOM   13402 O  O   . VAL D 1 389 ? -39.776 4.366   -27.964 1.00 35.97  ? 389 VAL D O   1 
ATOM   13403 C  CB  . VAL D 1 389 ? -40.426 7.257   -29.569 1.00 38.65  ? 389 VAL D CB  1 
ATOM   13404 C  CG1 . VAL D 1 389 ? -39.108 6.700   -30.081 1.00 34.37  ? 389 VAL D CG1 1 
ATOM   13405 C  CG2 . VAL D 1 389 ? -41.303 7.657   -30.728 1.00 40.09  ? 389 VAL D CG2 1 
ATOM   13406 N  N   . LEU D 1 390 ? -39.681 6.231   -26.711 1.00 41.88  ? 390 LEU D N   1 
ATOM   13407 C  CA  . LEU D 1 390 ? -38.750 5.611   -25.771 1.00 40.69  ? 390 LEU D CA  1 
ATOM   13408 C  C   . LEU D 1 390 ? -39.405 4.478   -24.990 1.00 42.15  ? 390 LEU D C   1 
ATOM   13409 O  O   . LEU D 1 390 ? -38.724 3.522   -24.601 1.00 42.08  ? 390 LEU D O   1 
ATOM   13410 C  CB  . LEU D 1 390 ? -38.182 6.671   -24.828 1.00 38.68  ? 390 LEU D CB  1 
ATOM   13411 C  CG  . LEU D 1 390 ? -37.441 7.793   -25.562 1.00 39.92  ? 390 LEU D CG  1 
ATOM   13412 C  CD1 . LEU D 1 390 ? -37.160 8.958   -24.647 1.00 41.85  ? 390 LEU D CD1 1 
ATOM   13413 C  CD2 . LEU D 1 390 ? -36.156 7.270   -26.192 1.00 37.79  ? 390 LEU D CD2 1 
ATOM   13414 N  N   . LYS D 1 391 ? -40.721 4.549   -24.769 1.00 46.26  ? 391 LYS D N   1 
ATOM   13415 C  CA  . LYS D 1 391 ? -41.405 3.455   -24.082 1.00 48.07  ? 391 LYS D CA  1 
ATOM   13416 C  C   . LYS D 1 391 ? -41.363 2.177   -24.912 1.00 40.15  ? 391 LYS D C   1 
ATOM   13417 O  O   . LYS D 1 391 ? -41.016 1.104   -24.405 1.00 43.71  ? 391 LYS D O   1 
ATOM   13418 C  CB  . LYS D 1 391 ? -42.850 3.852   -23.762 1.00 46.20  ? 391 LYS D CB  1 
ATOM   13419 C  CG  . LYS D 1 391 ? -43.752 2.708   -23.264 1.00 46.93  ? 391 LYS D CG  1 
ATOM   13420 C  CD  . LYS D 1 391 ? -45.215 3.165   -23.218 1.00 50.57  ? 391 LYS D CD  1 
ATOM   13421 C  CE  . LYS D 1 391 ? -45.787 3.310   -24.639 1.00 55.34  ? 391 LYS D CE  1 
ATOM   13422 N  NZ  . LYS D 1 391 ? -46.579 4.560   -24.830 1.00 44.94  ? 391 LYS D NZ  1 
ATOM   13423 N  N   . ALA D 1 392 ? -41.716 2.268   -26.193 1.00 45.27  ? 392 ALA D N   1 
ATOM   13424 C  CA  . ALA D 1 392 ? -41.739 1.070   -27.021 1.00 41.11  ? 392 ALA D CA  1 
ATOM   13425 C  C   . ALA D 1 392 ? -40.343 0.506   -27.218 1.00 44.11  ? 392 ALA D C   1 
ATOM   13426 O  O   . ALA D 1 392 ? -40.181 -0.715  -27.301 1.00 47.06  ? 392 ALA D O   1 
ATOM   13427 C  CB  . ALA D 1 392 ? -42.385 1.366   -28.373 1.00 45.85  ? 392 ALA D CB  1 
ATOM   13428 N  N   . LEU D 1 393 ? -39.328 1.375   -27.301 1.00 46.66  ? 393 LEU D N   1 
ATOM   13429 C  CA  . LEU D 1 393 ? -37.956 0.895   -27.455 1.00 43.90  ? 393 LEU D CA  1 
ATOM   13430 C  C   . LEU D 1 393 ? -37.531 0.079   -26.245 1.00 35.88  ? 393 LEU D C   1 
ATOM   13431 O  O   . LEU D 1 393 ? -36.914 -0.981  -26.383 1.00 36.45  ? 393 LEU D O   1 
ATOM   13432 C  CB  . LEU D 1 393 ? -37.007 2.078   -27.675 1.00 38.40  ? 393 LEU D CB  1 
ATOM   13433 C  CG  . LEU D 1 393 ? -37.141 2.744   -29.045 1.00 40.71  ? 393 LEU D CG  1 
ATOM   13434 C  CD1 . LEU D 1 393 ? -36.404 4.073   -29.095 1.00 40.15  ? 393 LEU D CD1 1 
ATOM   13435 C  CD2 . LEU D 1 393 ? -36.613 1.800   -30.083 1.00 38.54  ? 393 LEU D CD2 1 
ATOM   13436 N  N   . LYS D 1 394 ? -37.861 0.562   -25.051 1.00 45.69  ? 394 LYS D N   1 
ATOM   13437 C  CA  . LYS D 1 394 ? -37.587 -0.128  -23.795 1.00 42.48  ? 394 LYS D CA  1 
ATOM   13438 C  C   . LYS D 1 394 ? -38.264 -1.499  -23.764 1.00 45.91  ? 394 LYS D C   1 
ATOM   13439 O  O   . LYS D 1 394 ? -37.580 -2.529  -23.820 1.00 44.81  ? 394 LYS D O   1 
ATOM   13440 C  CB  . LYS D 1 394 ? -38.038 0.758   -22.635 1.00 45.56  ? 394 LYS D CB  1 
ATOM   13441 C  CG  . LYS D 1 394 ? -37.765 0.230   -21.236 1.00 43.06  ? 394 LYS D CG  1 
ATOM   13442 C  CD  . LYS D 1 394 ? -37.777 1.397   -20.234 1.00 46.01  ? 394 LYS D CD  1 
ATOM   13443 C  CE  . LYS D 1 394 ? -37.991 0.913   -18.794 1.00 45.28  ? 394 LYS D CE  1 
ATOM   13444 N  NZ  . LYS D 1 394 ? -36.751 0.886   -17.983 1.00 39.79  ? 394 LYS D NZ  1 
ATOM   13445 N  N   . ASP D 1 395 ? -39.607 -1.527  -23.728 1.00 48.28  ? 395 ASP D N   1 
ATOM   13446 C  CA  . ASP D 1 395 ? -40.334 -2.800  -23.657 1.00 46.55  ? 395 ASP D CA  1 
ATOM   13447 C  C   . ASP D 1 395 ? -39.876 -3.789  -24.727 1.00 45.43  ? 395 ASP D C   1 
ATOM   13448 O  O   . ASP D 1 395 ? -39.979 -5.003  -24.537 1.00 44.89  ? 395 ASP D O   1 
ATOM   13449 C  CB  . ASP D 1 395 ? -41.847 -2.563  -23.774 1.00 43.98  ? 395 ASP D CB  1 
ATOM   13450 C  CG  . ASP D 1 395 ? -42.341 -1.420  -22.883 1.00 48.48  ? 395 ASP D CG  1 
ATOM   13451 O  OD1 . ASP D 1 395 ? -41.718 -1.154  -21.825 1.00 44.05  ? 395 ASP D OD1 1 
ATOM   13452 O  OD2 . ASP D 1 395 ? -43.357 -0.781  -23.250 1.00 46.75  ? 395 ASP D OD2 1 
ATOM   13453 N  N   . ALA D 1 396 ? -39.335 -3.301  -25.839 1.00 46.10  ? 396 ALA D N   1 
ATOM   13454 C  CA  . ALA D 1 396 ? -38.863 -4.199  -26.888 1.00 47.78  ? 396 ALA D CA  1 
ATOM   13455 C  C   . ALA D 1 396 ? -37.429 -4.679  -26.675 1.00 39.04  ? 396 ALA D C   1 
ATOM   13456 O  O   . ALA D 1 396 ? -36.933 -5.466  -27.487 1.00 46.21  ? 396 ALA D O   1 
ATOM   13457 C  CB  . ALA D 1 396 ? -38.992 -3.525  -28.257 1.00 50.74  ? 396 ALA D CB  1 
ATOM   13458 N  N   . GLY D 1 397 ? -36.749 -4.230  -25.615 1.00 42.46  ? 397 GLY D N   1 
ATOM   13459 C  CA  . GLY D 1 397 ? -35.434 -4.740  -25.273 1.00 39.94  ? 397 GLY D CA  1 
ATOM   13460 C  C   . GLY D 1 397 ? -34.248 -3.984  -25.842 1.00 43.12  ? 397 GLY D C   1 
ATOM   13461 O  O   . GLY D 1 397 ? -33.097 -4.348  -25.546 1.00 43.42  ? 397 GLY D O   1 
ATOM   13462 N  N   . TYR D 1 398 ? -34.475 -2.948  -26.638 1.00 41.84  ? 398 TYR D N   1 
ATOM   13463 C  CA  . TYR D 1 398 ? -33.357 -2.230  -27.240 1.00 45.05  ? 398 TYR D CA  1 
ATOM   13464 C  C   . TYR D 1 398 ? -32.549 -1.525  -26.160 1.00 39.74  ? 398 TYR D C   1 
ATOM   13465 O  O   . TYR D 1 398 ? -33.087 -0.722  -25.392 1.00 43.46  ? 398 TYR D O   1 
ATOM   13466 C  CB  . TYR D 1 398 ? -33.850 -1.223  -28.277 1.00 43.72  ? 398 TYR D CB  1 
ATOM   13467 C  CG  . TYR D 1 398 ? -32.723 -0.462  -28.960 1.00 43.16  ? 398 TYR D CG  1 
ATOM   13468 C  CD1 . TYR D 1 398 ? -31.985 -1.043  -29.980 1.00 44.76  ? 398 TYR D CD1 1 
ATOM   13469 C  CD2 . TYR D 1 398 ? -32.403 0.831   -28.580 1.00 40.58  ? 398 TYR D CD2 1 
ATOM   13470 C  CE1 . TYR D 1 398 ? -30.965 -0.352  -30.600 1.00 35.69  ? 398 TYR D CE1 1 
ATOM   13471 C  CE2 . TYR D 1 398 ? -31.390 1.526   -29.202 1.00 40.28  ? 398 TYR D CE2 1 
ATOM   13472 C  CZ  . TYR D 1 398 ? -30.678 0.930   -30.205 1.00 38.46  ? 398 TYR D CZ  1 
ATOM   13473 O  OH  . TYR D 1 398 ? -29.653 1.633   -30.816 1.00 43.13  ? 398 TYR D OH  1 
ATOM   13474 N  N   . THR D 1 399 ? -31.256 -1.822  -26.103 1.00 41.41  ? 399 THR D N   1 
ATOM   13475 C  CA  . THR D 1 399 ? -30.342 -1.160  -25.181 1.00 43.73  ? 399 THR D CA  1 
ATOM   13476 C  C   . THR D 1 399 ? -29.154 -0.536  -25.925 1.00 43.65  ? 399 THR D C   1 
ATOM   13477 O  O   . THR D 1 399 ? -28.054 -0.415  -25.374 1.00 37.58  ? 399 THR D O   1 
ATOM   13478 C  CB  . THR D 1 399 ? -29.864 -2.146  -24.115 1.00 40.10  ? 399 THR D CB  1 
ATOM   13479 O  OG1 . THR D 1 399 ? -29.249 -3.263  -24.759 1.00 43.37  ? 399 THR D OG1 1 
ATOM   13480 C  CG2 . THR D 1 399 ? -31.042 -2.652  -23.268 1.00 43.95  ? 399 THR D CG2 1 
ATOM   13481 N  N   . GLY D 1 400 ? -29.359 -0.133  -27.181 1.00 47.37  ? 400 GLY D N   1 
ATOM   13482 C  CA  . GLY D 1 400 ? -28.302 0.432   -28.002 1.00 34.08  ? 400 GLY D CA  1 
ATOM   13483 C  C   . GLY D 1 400 ? -28.209 1.934   -27.870 1.00 41.88  ? 400 GLY D C   1 
ATOM   13484 O  O   . GLY D 1 400 ? -28.793 2.546   -26.970 1.00 39.98  ? 400 GLY D O   1 
ATOM   13485 N  N   . TYR D 1 401 ? -27.489 2.541   -28.817 1.00 36.18  ? 401 TYR D N   1 
ATOM   13486 C  CA  . TYR D 1 401 ? -27.276 3.977   -28.803 1.00 34.29  ? 401 TYR D CA  1 
ATOM   13487 C  C   . TYR D 1 401 ? -28.490 4.738   -29.327 1.00 33.04  ? 401 TYR D C   1 
ATOM   13488 O  O   . TYR D 1 401 ? -29.225 4.262   -30.192 1.00 35.95  ? 401 TYR D O   1 
ATOM   13489 C  CB  . TYR D 1 401 ? -26.043 4.331   -29.642 1.00 34.42  ? 401 TYR D CB  1 
ATOM   13490 C  CG  . TYR D 1 401 ? -24.779 4.433   -28.839 1.00 29.22  ? 401 TYR D CG  1 
ATOM   13491 C  CD1 . TYR D 1 401 ? -24.488 5.591   -28.128 1.00 35.93  ? 401 TYR D CD1 1 
ATOM   13492 C  CD2 . TYR D 1 401 ? -23.884 3.378   -28.769 1.00 32.04  ? 401 TYR D CD2 1 
ATOM   13493 C  CE1 . TYR D 1 401 ? -23.341 5.704   -27.383 1.00 30.66  ? 401 TYR D CE1 1 
ATOM   13494 C  CE2 . TYR D 1 401 ? -22.723 3.478   -28.022 1.00 30.97  ? 401 TYR D CE2 1 
ATOM   13495 C  CZ  . TYR D 1 401 ? -22.459 4.651   -27.329 1.00 33.97  ? 401 TYR D CZ  1 
ATOM   13496 O  OH  . TYR D 1 401 ? -21.323 4.789   -26.566 1.00 27.56  ? 401 TYR D OH  1 
ATOM   13497 N  N   . LEU D 1 402 ? -28.691 5.933   -28.788 1.00 31.27  ? 402 LEU D N   1 
ATOM   13498 C  CA  . LEU D 1 402 ? -29.517 6.961   -29.412 1.00 34.13  ? 402 LEU D CA  1 
ATOM   13499 C  C   . LEU D 1 402 ? -28.579 8.116   -29.751 1.00 30.92  ? 402 LEU D C   1 
ATOM   13500 O  O   . LEU D 1 402 ? -28.096 8.821   -28.856 1.00 32.68  ? 402 LEU D O   1 
ATOM   13501 C  CB  . LEU D 1 402 ? -30.653 7.422   -28.501 1.00 28.86  ? 402 LEU D CB  1 
ATOM   13502 C  CG  . LEU D 1 402 ? -31.526 6.346   -27.845 1.00 35.73  ? 402 LEU D CG  1 
ATOM   13503 C  CD1 . LEU D 1 402 ? -32.600 7.041   -27.003 1.00 34.53  ? 402 LEU D CD1 1 
ATOM   13504 C  CD2 . LEU D 1 402 ? -32.133 5.333   -28.872 1.00 28.61  ? 402 LEU D CD2 1 
ATOM   13505 N  N   . SER D 1 403 ? -28.336 8.317   -31.043 1.00 38.23  ? 403 SER D N   1 
ATOM   13506 C  CA  . SER D 1 403 ? -27.337 9.264   -31.528 1.00 31.69  ? 403 SER D CA  1 
ATOM   13507 C  C   . SER D 1 403 ? -28.048 10.505  -32.061 1.00 32.15  ? 403 SER D C   1 
ATOM   13508 O  O   . SER D 1 403 ? -28.760 10.435  -33.066 1.00 25.82  ? 403 SER D O   1 
ATOM   13509 C  CB  . SER D 1 403 ? -26.479 8.591   -32.594 1.00 30.66  ? 403 SER D CB  1 
ATOM   13510 O  OG  . SER D 1 403 ? -25.307 9.337   -32.884 1.00 33.96  ? 403 SER D OG  1 
ATOM   13511 N  N   . SER D 1 404 ? -27.867 11.632  -31.365 1.00 30.80  ? 404 SER D N   1 
ATOM   13512 C  CA  . SER D 1 404 ? -28.521 12.889  -31.710 1.00 28.86  ? 404 SER D CA  1 
ATOM   13513 C  C   . SER D 1 404 ? -28.273 13.284  -33.163 1.00 29.55  ? 404 SER D C   1 
ATOM   13514 O  O   . SER D 1 404 ? -27.132 13.280  -33.631 1.00 26.81  ? 404 SER D O   1 
ATOM   13515 C  CB  . SER D 1 404 ? -28.008 14.005  -30.792 1.00 34.29  ? 404 SER D CB  1 
ATOM   13516 O  OG  . SER D 1 404 ? -28.523 13.898  -29.472 1.00 31.44  ? 404 SER D OG  1 
ATOM   13517 N  N   . GLU D 1 405 ? -29.354 13.665  -33.872 1.00 31.53  ? 405 GLU D N   1 
ATOM   13518 C  CA  . GLU D 1 405 ? -29.264 14.234  -35.226 1.00 35.04  ? 405 GLU D CA  1 
ATOM   13519 C  C   . GLU D 1 405 ? -30.126 15.488  -35.274 1.00 26.74  ? 405 GLU D C   1 
ATOM   13520 O  O   . GLU D 1 405 ? -31.257 15.449  -35.751 1.00 35.57  ? 405 GLU D O   1 
ATOM   13521 C  CB  . GLU D 1 405 ? -29.693 13.209  -36.304 1.00 31.70  ? 405 GLU D CB  1 
ATOM   13522 C  CG  . GLU D 1 405 ? -28.568 12.304  -36.762 1.00 37.97  ? 405 GLU D CG  1 
ATOM   13523 C  CD  . GLU D 1 405 ? -28.856 11.547  -38.054 1.00 34.81  ? 405 GLU D CD  1 
ATOM   13524 O  OE1 . GLU D 1 405 ? -30.031 11.408  -38.451 1.00 43.73  ? 405 GLU D OE1 1 
ATOM   13525 O  OE2 . GLU D 1 405 ? -27.880 11.105  -38.697 1.00 42.06  ? 405 GLU D OE2 1 
ATOM   13526 N  N   . TYR D 1 406 ? -29.604 16.609  -34.785 1.00 26.91  ? 406 TYR D N   1 
ATOM   13527 C  CA  . TYR D 1 406 ? -30.386 17.837  -34.831 1.00 30.43  ? 406 TYR D CA  1 
ATOM   13528 C  C   . TYR D 1 406 ? -30.524 18.328  -36.265 1.00 31.75  ? 406 TYR D C   1 
ATOM   13529 O  O   . TYR D 1 406 ? -29.528 18.478  -36.977 1.00 37.47  ? 406 TYR D O   1 
ATOM   13530 C  CB  . TYR D 1 406 ? -29.739 18.927  -34.001 1.00 31.19  ? 406 TYR D CB  1 
ATOM   13531 C  CG  . TYR D 1 406 ? -30.355 20.289  -34.245 1.00 34.39  ? 406 TYR D CG  1 
ATOM   13532 C  CD1 . TYR D 1 406 ? -31.557 20.641  -33.649 1.00 33.71  ? 406 TYR D CD1 1 
ATOM   13533 C  CD2 . TYR D 1 406 ? -29.739 21.221  -35.070 1.00 30.82  ? 406 TYR D CD2 1 
ATOM   13534 C  CE1 . TYR D 1 406 ? -32.119 21.892  -33.849 1.00 33.19  ? 406 TYR D CE1 1 
ATOM   13535 C  CE2 . TYR D 1 406 ? -30.293 22.472  -35.278 1.00 32.93  ? 406 TYR D CE2 1 
ATOM   13536 C  CZ  . TYR D 1 406 ? -31.495 22.803  -34.671 1.00 33.69  ? 406 TYR D CZ  1 
ATOM   13537 O  OH  . TYR D 1 406 ? -32.077 24.050  -34.863 1.00 32.40  ? 406 TYR D OH  1 
ATOM   13538 N  N   . GLU D 1 407 ? -31.770 18.543  -36.680 1.00 35.60  ? 407 GLU D N   1 
ATOM   13539 C  CA  . GLU D 1 407 ? -32.053 18.905  -38.091 1.00 38.52  ? 407 GLU D CA  1 
ATOM   13540 C  C   . GLU D 1 407 ? -33.107 20.005  -38.133 1.00 35.98  ? 407 GLU D C   1 
ATOM   13541 O  O   . GLU D 1 407 ? -34.063 19.870  -38.891 1.00 39.55  ? 407 GLU D O   1 
ATOM   13542 C  CB  . GLU D 1 407 ? -32.480 17.663  -38.873 1.00 40.39  ? 407 GLU D CB  1 
ATOM   13543 C  CG  . GLU D 1 407 ? -32.070 17.673  -40.334 1.00 46.68  ? 407 GLU D CG  1 
ATOM   13544 C  CD  . GLU D 1 407 ? -32.743 16.589  -41.159 1.00 49.89  ? 407 GLU D CD  1 
ATOM   13545 O  OE1 . GLU D 1 407 ? -33.975 16.634  -41.291 1.00 47.97  ? 407 GLU D OE1 1 
ATOM   13546 O  OE2 . GLU D 1 407 ? -32.035 15.695  -41.653 1.00 49.65  ? 407 GLU D OE2 1 
ATOM   13547 N  N   . GLY D 1 408 ? -32.933 21.028  -37.315 1.00 39.92  ? 408 GLY D N   1 
ATOM   13548 C  CA  . GLY D 1 408 ? -33.807 22.200  -37.389 1.00 36.28  ? 408 GLY D CA  1 
ATOM   13549 C  C   . GLY D 1 408 ? -33.053 23.383  -37.959 1.00 38.37  ? 408 GLY D C   1 
ATOM   13550 O  O   . GLY D 1 408 ? -31.968 23.187  -38.500 1.00 38.93  ? 408 GLY D O   1 
ATOM   13551 N  N   . GLU D 1 409 ? -33.603 24.574  -37.796 1.00 38.62  ? 409 GLU D N   1 
ATOM   13552 C  CA  . GLU D 1 409 ? -32.940 25.819  -38.232 1.00 39.88  ? 409 GLU D CA  1 
ATOM   13553 C  C   . GLU D 1 409 ? -31.441 25.737  -37.956 1.00 40.94  ? 409 GLU D C   1 
ATOM   13554 O  O   . GLU D 1 409 ? -31.067 25.541  -36.797 1.00 40.51  ? 409 GLU D O   1 
ATOM   13555 C  CB  . GLU D 1 409 ? -33.573 26.979  -37.470 1.00 42.20  ? 409 GLU D CB  1 
ATOM   13556 C  CG  . GLU D 1 409 ? -34.463 26.513  -36.333 1.00 48.94  ? 409 GLU D CG  1 
ATOM   13557 C  CD  . GLU D 1 409 ? -35.276 27.594  -35.645 1.00 51.35  ? 409 GLU D CD  1 
ATOM   13558 O  OE1 . GLU D 1 409 ? -34.776 28.725  -35.535 1.00 60.30  ? 409 GLU D OE1 1 
ATOM   13559 O  OE2 . GLU D 1 409 ? -36.407 27.297  -35.220 1.00 55.93  ? 409 GLU D OE2 1 
ATOM   13560 N  N   . ARG D 1 410 ? -30.631 25.927  -38.993 1.00 42.90  ? 410 ARG D N   1 
ATOM   13561 C  CA  . ARG D 1 410 ? -29.155 25.911  -38.854 1.00 34.57  ? 410 ARG D CA  1 
ATOM   13562 C  C   . ARG D 1 410 ? -28.677 27.319  -38.502 1.00 33.97  ? 410 ARG D C   1 
ATOM   13563 O  O   . ARG D 1 410 ? -27.693 27.772  -39.089 1.00 32.22  ? 410 ARG D O   1 
ATOM   13564 C  CB  . ARG D 1 410 ? -28.530 25.411  -40.156 1.00 36.31  ? 410 ARG D CB  1 
ATOM   13565 C  CG  . ARG D 1 410 ? -29.027 24.042  -40.594 1.00 37.56  ? 410 ARG D CG  1 
ATOM   13566 C  CD  . ARG D 1 410 ? -28.304 22.939  -39.854 1.00 29.51  ? 410 ARG D CD  1 
ATOM   13567 N  NE  . ARG D 1 410 ? -28.785 21.607  -40.180 1.00 36.00  ? 410 ARG D NE  1 
ATOM   13568 C  CZ  . ARG D 1 410 ? -28.755 20.577  -39.346 1.00 33.91  ? 410 ARG D CZ  1 
ATOM   13569 N  NH1 . ARG D 1 410 ? -28.363 20.749  -38.099 1.00 32.84  ? 410 ARG D NH1 1 
ATOM   13570 N  NH2 . ARG D 1 410 ? -29.112 19.377  -39.761 1.00 33.67  ? 410 ARG D NH2 1 
ATOM   13571 N  N   . GLU D 1 411 ? -29.378 27.989  -37.596 1.00 32.82  ? 411 GLU D N   1 
ATOM   13572 C  CA  . GLU D 1 411 ? -28.898 29.283  -37.148 1.00 33.86  ? 411 GLU D CA  1 
ATOM   13573 C  C   . GLU D 1 411 ? -27.600 29.081  -36.373 1.00 35.84  ? 411 GLU D C   1 
ATOM   13574 O  O   . GLU D 1 411 ? -27.534 28.192  -35.518 1.00 34.87  ? 411 GLU D O   1 
ATOM   13575 C  CB  . GLU D 1 411 ? -29.956 29.956  -36.285 1.00 37.51  ? 411 GLU D CB  1 
ATOM   13576 C  CG  . GLU D 1 411 ? -29.565 31.333  -35.791 1.00 41.51  ? 411 GLU D CG  1 
ATOM   13577 C  CD  . GLU D 1 411 ? -30.174 31.634  -34.443 1.00 53.50  ? 411 GLU D CD  1 
ATOM   13578 O  OE1 . GLU D 1 411 ? -29.861 32.707  -33.875 1.00 63.60  ? 411 GLU D OE1 1 
ATOM   13579 O  OE2 . GLU D 1 411 ? -30.972 30.790  -33.958 1.00 58.23  ? 411 GLU D OE2 1 
ATOM   13580 N  N   . PRO D 1 412 ? -26.553 29.859  -36.648 1.00 33.58  ? 412 PRO D N   1 
ATOM   13581 C  CA  . PRO D 1 412 ? -25.241 29.568  -36.051 1.00 31.87  ? 412 PRO D CA  1 
ATOM   13582 C  C   . PRO D 1 412 ? -25.340 29.337  -34.546 1.00 31.33  ? 412 PRO D C   1 
ATOM   13583 O  O   . PRO D 1 412 ? -26.096 30.013  -33.843 1.00 32.99  ? 412 PRO D O   1 
ATOM   13584 C  CB  . PRO D 1 412 ? -24.418 30.815  -36.381 1.00 26.72  ? 412 PRO D CB  1 
ATOM   13585 C  CG  . PRO D 1 412 ? -25.095 31.414  -37.584 1.00 26.74  ? 412 PRO D CG  1 
ATOM   13586 C  CD  . PRO D 1 412 ? -26.544 31.091  -37.461 1.00 35.71  ? 412 PRO D CD  1 
ATOM   13587 N  N   . TRP D 1 413 ? -24.618 28.317  -34.085 1.00 31.44  ? 413 TRP D N   1 
ATOM   13588 C  CA  . TRP D 1 413 ? -24.498 27.882  -32.692 1.00 24.60  ? 413 TRP D CA  1 
ATOM   13589 C  C   . TRP D 1 413 ? -25.756 27.243  -32.131 1.00 27.07  ? 413 TRP D C   1 
ATOM   13590 O  O   . TRP D 1 413 ? -25.692 26.592  -31.087 1.00 27.92  ? 413 TRP D O   1 
ATOM   13591 C  CB  . TRP D 1 413 ? -24.085 29.038  -31.786 1.00 25.41  ? 413 TRP D CB  1 
ATOM   13592 C  CG  . TRP D 1 413 ? -22.713 29.488  -32.064 1.00 26.25  ? 413 TRP D CG  1 
ATOM   13593 C  CD1 . TRP D 1 413 ? -21.550 28.855  -31.718 1.00 26.97  ? 413 TRP D CD1 1 
ATOM   13594 C  CD2 . TRP D 1 413 ? -22.336 30.665  -32.775 1.00 23.40  ? 413 TRP D CD2 1 
ATOM   13595 N  NE1 . TRP D 1 413 ? -20.466 29.579  -32.170 1.00 25.88  ? 413 TRP D NE1 1 
ATOM   13596 C  CE2 . TRP D 1 413 ? -20.927 30.693  -32.822 1.00 26.04  ? 413 TRP D CE2 1 
ATOM   13597 C  CE3 . TRP D 1 413 ? -23.050 31.707  -33.357 1.00 23.12  ? 413 TRP D CE3 1 
ATOM   13598 C  CZ2 . TRP D 1 413 ? -20.230 31.722  -33.434 1.00 29.23  ? 413 TRP D CZ2 1 
ATOM   13599 C  CZ3 . TRP D 1 413 ? -22.361 32.717  -33.963 1.00 26.86  ? 413 TRP D CZ3 1 
ATOM   13600 C  CH2 . TRP D 1 413 ? -20.968 32.721  -34.007 1.00 25.40  ? 413 TRP D CH2 1 
ATOM   13601 N  N   . ARG D 1 414 ? -26.898 27.396  -32.804 1.00 28.85  ? 414 ARG D N   1 
ATOM   13602 C  CA  . ARG D 1 414 ? -28.153 26.977  -32.186 1.00 31.26  ? 414 ARG D CA  1 
ATOM   13603 C  C   . ARG D 1 414 ? -28.183 25.485  -31.902 1.00 32.82  ? 414 ARG D C   1 
ATOM   13604 O  O   . ARG D 1 414 ? -28.846 25.047  -30.953 1.00 31.01  ? 414 ARG D O   1 
ATOM   13605 C  CB  . ARG D 1 414 ? -29.331 27.381  -33.063 1.00 32.19  ? 414 ARG D CB  1 
ATOM   13606 C  CG  . ARG D 1 414 ? -30.683 27.024  -32.480 1.00 33.22  ? 414 ARG D CG  1 
ATOM   13607 C  CD  . ARG D 1 414 ? -31.742 27.127  -33.548 1.00 40.25  ? 414 ARG D CD  1 
ATOM   13608 N  NE  . ARG D 1 414 ? -32.894 26.284  -33.266 1.00 37.49  ? 414 ARG D NE  1 
ATOM   13609 C  CZ  . ARG D 1 414 ? -33.866 26.623  -32.437 1.00 40.62  ? 414 ARG D CZ  1 
ATOM   13610 N  NH1 . ARG D 1 414 ? -33.818 27.752  -31.747 1.00 41.64  ? 414 ARG D NH1 1 
ATOM   13611 N  NH2 . ARG D 1 414 ? -34.913 25.812  -32.302 1.00 46.09  ? 414 ARG D NH2 1 
ATOM   13612 N  N   . SER D 1 415 ? -27.467 24.688  -32.695 1.00 28.88  ? 415 SER D N   1 
ATOM   13613 C  CA  . SER D 1 415 ? -27.491 23.247  -32.493 1.00 29.71  ? 415 SER D CA  1 
ATOM   13614 C  C   . SER D 1 415 ? -26.804 22.807  -31.205 1.00 28.03  ? 415 SER D C   1 
ATOM   13615 O  O   . SER D 1 415 ? -26.948 21.649  -30.818 1.00 27.81  ? 415 SER D O   1 
ATOM   13616 C  CB  . SER D 1 415 ? -26.836 22.546  -33.674 1.00 28.59  ? 415 SER D CB  1 
ATOM   13617 O  OG  . SER D 1 415 ? -25.449 22.761  -33.627 1.00 30.23  ? 415 SER D OG  1 
ATOM   13618 N  N   . ILE D 1 416 ? -26.051 23.676  -30.539 1.00 32.27  ? 416 ILE D N   1 
ATOM   13619 C  CA  . ILE D 1 416 ? -25.419 23.259  -29.293 1.00 32.40  ? 416 ILE D CA  1 
ATOM   13620 C  C   . ILE D 1 416 ? -26.450 23.195  -28.179 1.00 27.89  ? 416 ILE D C   1 
ATOM   13621 O  O   . ILE D 1 416 ? -26.553 22.183  -27.482 1.00 39.21  ? 416 ILE D O   1 
ATOM   13622 C  CB  . ILE D 1 416 ? -24.240 24.178  -28.934 1.00 28.94  ? 416 ILE D CB  1 
ATOM   13623 C  CG1 . ILE D 1 416 ? -23.114 24.027  -29.968 1.00 25.77  ? 416 ILE D CG1 1 
ATOM   13624 C  CG2 . ILE D 1 416 ? -23.740 23.864  -27.551 1.00 30.54  ? 416 ILE D CG2 1 
ATOM   13625 C  CD1 . ILE D 1 416 ? -22.119 25.151  -29.937 1.00 20.95  ? 416 ILE D CD1 1 
ATOM   13626 N  N   . GLU D 1 417 ? -27.234 24.268  -28.000 1.00 33.00  ? 417 GLU D N   1 
ATOM   13627 C  CA  . GLU D 1 417 ? -28.329 24.242  -27.027 1.00 31.21  ? 417 GLU D CA  1 
ATOM   13628 C  C   . GLU D 1 417 ? -29.315 23.128  -27.336 1.00 31.88  ? 417 GLU D C   1 
ATOM   13629 O  O   . GLU D 1 417 ? -29.878 22.507  -26.426 1.00 35.92  ? 417 GLU D O   1 
ATOM   13630 C  CB  . GLU D 1 417 ? -29.063 25.585  -27.005 1.00 29.68  ? 417 GLU D CB  1 
ATOM   13631 C  CG  . GLU D 1 417 ? -28.744 26.450  -25.795 1.00 32.99  ? 417 GLU D CG  1 
ATOM   13632 C  CD  . GLU D 1 417 ? -28.953 25.695  -24.485 1.00 34.37  ? 417 GLU D CD  1 
ATOM   13633 O  OE1 . GLU D 1 417 ? -30.096 25.260  -24.219 1.00 35.92  ? 417 GLU D OE1 1 
ATOM   13634 O  OE2 . GLU D 1 417 ? -27.963 25.495  -23.746 1.00 35.94  ? 417 GLU D OE2 1 
ATOM   13635 N  N   . GLN D 1 418 ? -29.539 22.859  -28.618 1.00 34.69  ? 418 GLN D N   1 
ATOM   13636 C  CA  . GLN D 1 418 ? -30.579 21.913  -28.997 1.00 31.74  ? 418 GLN D CA  1 
ATOM   13637 C  C   . GLN D 1 418 ? -30.172 20.485  -28.687 1.00 32.87  ? 418 GLN D C   1 
ATOM   13638 O  O   . GLN D 1 418 ? -30.994 19.699  -28.202 1.00 34.00  ? 418 GLN D O   1 
ATOM   13639 C  CB  . GLN D 1 418 ? -30.919 22.081  -30.473 1.00 29.43  ? 418 GLN D CB  1 
ATOM   13640 C  CG  . GLN D 1 418 ? -31.591 23.419  -30.770 1.00 33.01  ? 418 GLN D CG  1 
ATOM   13641 C  CD  . GLN D 1 418 ? -32.992 23.478  -30.206 1.00 38.50  ? 418 GLN D CD  1 
ATOM   13642 O  OE1 . GLN D 1 418 ? -33.778 22.538  -30.378 1.00 32.51  ? 418 GLN D OE1 1 
ATOM   13643 N  NE2 . GLN D 1 418 ? -33.315 24.579  -29.515 1.00 38.31  ? 418 GLN D NE2 1 
ATOM   13644 N  N   . VAL D 1 419 ? -28.919 20.117  -28.966 1.00 26.76  ? 419 VAL D N   1 
ATOM   13645 C  CA  . VAL D 1 419 ? -28.527 18.745  -28.687 1.00 32.28  ? 419 VAL D CA  1 
ATOM   13646 C  C   . VAL D 1 419 ? -28.506 18.506  -27.176 1.00 29.85  ? 419 VAL D C   1 
ATOM   13647 O  O   . VAL D 1 419 ? -28.923 17.448  -26.702 1.00 30.91  ? 419 VAL D O   1 
ATOM   13648 C  CB  . VAL D 1 419 ? -27.186 18.405  -29.364 1.00 29.06  ? 419 VAL D CB  1 
ATOM   13649 C  CG1 . VAL D 1 419 ? -26.740 17.024  -28.956 1.00 30.77  ? 419 VAL D CG1 1 
ATOM   13650 C  CG2 . VAL D 1 419 ? -27.352 18.401  -30.873 1.00 32.85  ? 419 VAL D CG2 1 
ATOM   13651 N  N   . ARG D 1 420 ? -28.074 19.506  -26.397 1.00 32.73  ? 420 ARG D N   1 
ATOM   13652 C  CA  . ARG D 1 420 ? -28.142 19.395  -24.942 1.00 31.82  ? 420 ARG D CA  1 
ATOM   13653 C  C   . ARG D 1 420 ? -29.579 19.205  -24.484 1.00 33.91  ? 420 ARG D C   1 
ATOM   13654 O  O   . ARG D 1 420 ? -29.871 18.318  -23.673 1.00 32.57  ? 420 ARG D O   1 
ATOM   13655 C  CB  . ARG D 1 420 ? -27.533 20.624  -24.273 1.00 27.82  ? 420 ARG D CB  1 
ATOM   13656 C  CG  . ARG D 1 420 ? -26.054 20.806  -24.566 1.00 30.99  ? 420 ARG D CG  1 
ATOM   13657 C  CD  . ARG D 1 420 ? -25.567 22.112  -24.025 1.00 33.53  ? 420 ARG D CD  1 
ATOM   13658 N  NE  . ARG D 1 420 ? -25.403 22.068  -22.579 1.00 32.62  ? 420 ARG D NE  1 
ATOM   13659 C  CZ  . ARG D 1 420 ? -24.378 21.496  -21.966 1.00 32.62  ? 420 ARG D CZ  1 
ATOM   13660 N  NH1 . ARG D 1 420 ? -23.382 20.953  -22.650 1.00 30.93  ? 420 ARG D NH1 1 
ATOM   13661 N  NH2 . ARG D 1 420 ? -24.357 21.459  -20.632 1.00 32.55  ? 420 ARG D NH2 1 
ATOM   13662 N  N   . ARG D 1 421 ? -30.491 20.027  -25.003 1.00 32.52  ? 421 ARG D N   1 
ATOM   13663 C  CA  . ARG D 1 421 ? -31.897 19.861  -24.660 1.00 32.41  ? 421 ARG D CA  1 
ATOM   13664 C  C   . ARG D 1 421 ? -32.380 18.456  -24.994 1.00 35.86  ? 421 ARG D C   1 
ATOM   13665 O  O   . ARG D 1 421 ? -33.087 17.827  -24.194 1.00 33.59  ? 421 ARG D O   1 
ATOM   13666 C  CB  . ARG D 1 421 ? -32.733 20.922  -25.371 1.00 30.58  ? 421 ARG D CB  1 
ATOM   13667 C  CG  . ARG D 1 421 ? -32.673 22.244  -24.669 1.00 29.68  ? 421 ARG D CG  1 
ATOM   13668 C  CD  . ARG D 1 421 ? -33.380 23.377  -25.392 1.00 32.05  ? 421 ARG D CD  1 
ATOM   13669 N  NE  . ARG D 1 421 ? -32.689 24.628  -25.101 1.00 31.76  ? 421 ARG D NE  1 
ATOM   13670 C  CZ  . ARG D 1 421 ? -33.050 25.828  -25.526 1.00 31.82  ? 421 ARG D CZ  1 
ATOM   13671 N  NH1 . ARG D 1 421 ? -34.141 26.010  -26.248 1.00 36.62  ? 421 ARG D NH1 1 
ATOM   13672 N  NH2 . ARG D 1 421 ? -32.298 26.875  -25.208 1.00 41.89  ? 421 ARG D NH2 1 
ATOM   13673 N  N   . GLN D 1 422 ? -31.972 17.918  -26.145 1.00 32.67  ? 422 GLN D N   1 
ATOM   13674 C  CA  . GLN D 1 422 ? -32.471 16.595  -26.496 1.00 31.22  ? 422 GLN D CA  1 
ATOM   13675 C  C   . GLN D 1 422 ? -31.957 15.538  -25.528 1.00 38.26  ? 422 GLN D C   1 
ATOM   13676 O  O   . GLN D 1 422 ? -32.711 14.649  -25.119 1.00 37.20  ? 422 GLN D O   1 
ATOM   13677 C  CB  . GLN D 1 422 ? -32.117 16.216  -27.929 1.00 31.25  ? 422 GLN D CB  1 
ATOM   13678 C  CG  . GLN D 1 422 ? -32.686 14.850  -28.283 1.00 31.77  ? 422 GLN D CG  1 
ATOM   13679 C  CD  . GLN D 1 422 ? -32.079 14.259  -29.533 1.00 37.21  ? 422 GLN D CD  1 
ATOM   13680 O  OE1 . GLN D 1 422 ? -30.900 14.475  -29.828 1.00 31.66  ? 422 GLN D OE1 1 
ATOM   13681 N  NE2 . GLN D 1 422 ? -32.877 13.486  -30.270 1.00 33.41  ? 422 GLN D NE2 1 
ATOM   13682 N  N   . HIS D 1 423 ? -30.683 15.619  -25.139 1.00 34.17  ? 423 HIS D N   1 
ATOM   13683 C  CA  . HIS D 1 423 ? -30.167 14.659  -24.172 1.00 36.66  ? 423 HIS D CA  1 
ATOM   13684 C  C   . HIS D 1 423 ? -30.833 14.837  -22.810 1.00 36.47  ? 423 HIS D C   1 
ATOM   13685 O  O   . HIS D 1 423 ? -31.145 13.855  -22.137 1.00 35.80  ? 423 HIS D O   1 
ATOM   13686 C  CB  . HIS D 1 423 ? -28.643 14.790  -24.071 1.00 34.93  ? 423 HIS D CB  1 
ATOM   13687 C  CG  . HIS D 1 423 ? -27.916 14.139  -25.206 1.00 36.39  ? 423 HIS D CG  1 
ATOM   13688 N  ND1 . HIS D 1 423 ? -27.263 12.932  -25.079 1.00 31.90  ? 423 HIS D ND1 1 
ATOM   13689 C  CD2 . HIS D 1 423 ? -27.780 14.507  -26.501 1.00 30.34  ? 423 HIS D CD2 1 
ATOM   13690 C  CE1 . HIS D 1 423 ? -26.731 12.598  -26.239 1.00 34.10  ? 423 HIS D CE1 1 
ATOM   13691 N  NE2 . HIS D 1 423 ? -27.034 13.536  -27.118 1.00 33.32  ? 423 HIS D NE2 1 
ATOM   13692 N  N   . SER D 1 424 ? -31.071 16.083  -22.395 1.00 40.06  ? 424 SER D N   1 
ATOM   13693 C  CA  . SER D 1 424 ? -31.750 16.314  -21.127 1.00 32.53  ? 424 SER D CA  1 
ATOM   13694 C  C   . SER D 1 424 ? -33.168 15.740  -21.153 1.00 44.23  ? 424 SER D C   1 
ATOM   13695 O  O   . SER D 1 424 ? -33.558 14.984  -20.253 1.00 39.25  ? 424 SER D O   1 
ATOM   13696 C  CB  . SER D 1 424 ? -31.753 17.808  -20.813 1.00 37.96  ? 424 SER D CB  1 
ATOM   13697 O  OG  . SER D 1 424 ? -32.318 18.059  -19.534 1.00 40.55  ? 424 SER D OG  1 
ATOM   13698 N  N   . LEU D 1 425 ? -33.944 16.049  -22.203 1.00 41.12  ? 425 LEU D N   1 
ATOM   13699 C  CA  . LEU D 1 425 ? -35.318 15.550  -22.275 1.00 39.02  ? 425 LEU D CA  1 
ATOM   13700 C  C   . LEU D 1 425 ? -35.371 14.020  -22.272 1.00 41.42  ? 425 LEU D C   1 
ATOM   13701 O  O   . LEU D 1 425 ? -36.112 13.417  -21.485 1.00 39.95  ? 425 LEU D O   1 
ATOM   13702 C  CB  . LEU D 1 425 ? -36.030 16.108  -23.509 1.00 40.36  ? 425 LEU D CB  1 
ATOM   13703 C  CG  . LEU D 1 425 ? -37.443 15.540  -23.725 1.00 46.78  ? 425 LEU D CG  1 
ATOM   13704 C  CD1 . LEU D 1 425 ? -38.362 15.986  -22.608 1.00 41.66  ? 425 LEU D CD1 1 
ATOM   13705 C  CD2 . LEU D 1 425 ? -38.040 15.922  -25.081 1.00 44.43  ? 425 LEU D CD2 1 
ATOM   13706 N  N   . ILE D 1 426 ? -34.604 13.368  -23.151 1.00 38.88  ? 426 ILE D N   1 
ATOM   13707 C  CA  . ILE D 1 426 ? -34.743 11.918  -23.309 1.00 33.76  ? 426 ILE D CA  1 
ATOM   13708 C  C   . ILE D 1 426 ? -34.358 11.192  -22.024 1.00 39.22  ? 426 ILE D C   1 
ATOM   13709 O  O   . ILE D 1 426 ? -35.093 10.329  -21.534 1.00 43.20  ? 426 ILE D O   1 
ATOM   13710 C  CB  . ILE D 1 426 ? -33.903 11.409  -24.495 1.00 39.44  ? 426 ILE D CB  1 
ATOM   13711 C  CG1 . ILE D 1 426 ? -34.476 11.864  -25.838 1.00 39.32  ? 426 ILE D CG1 1 
ATOM   13712 C  CG2 . ILE D 1 426 ? -33.790 9.883   -24.458 1.00 38.21  ? 426 ILE D CG2 1 
ATOM   13713 C  CD1 . ILE D 1 426 ? -34.067 10.954  -26.989 1.00 38.10  ? 426 ILE D CD1 1 
ATOM   13714 N  N   . ARG D 1 427 ? -33.172 11.484  -21.491 1.00 36.50  ? 427 ARG D N   1 
ATOM   13715 C  CA  . ARG D 1 427 ? -32.703 10.743  -20.324 1.00 40.39  ? 427 ARG D CA  1 
ATOM   13716 C  C   . ARG D 1 427 ? -33.720 10.828  -19.199 1.00 40.20  ? 427 ARG D C   1 
ATOM   13717 O  O   . ARG D 1 427 ? -34.001 9.825   -18.534 1.00 40.50  ? 427 ARG D O   1 
ATOM   13718 C  CB  . ARG D 1 427 ? -31.336 11.271  -19.871 1.00 43.01  ? 427 ARG D CB  1 
ATOM   13719 C  CG  . ARG D 1 427 ? -30.157 10.817  -20.735 1.00 37.97  ? 427 ARG D CG  1 
ATOM   13720 C  CD  . ARG D 1 427 ? -29.032 11.846  -20.712 1.00 43.05  ? 427 ARG D CD  1 
ATOM   13721 N  NE  . ARG D 1 427 ? -28.200 11.683  -19.532 1.00 48.10  ? 427 ARG D NE  1 
ATOM   13722 C  CZ  . ARG D 1 427 ? -26.974 11.178  -19.518 1.00 48.97  ? 427 ARG D CZ  1 
ATOM   13723 N  NH1 . ARG D 1 427 ? -26.328 10.895  -20.634 1.00 45.79  ? 427 ARG D NH1 1 
ATOM   13724 N  NH2 . ARG D 1 427 ? -26.376 10.966  -18.346 1.00 55.16  ? 427 ARG D NH2 1 
ATOM   13725 N  N   . GLN D 1 428 ? -34.321 12.009  -19.013 1.00 40.15  ? 428 GLN D N   1 
ATOM   13726 C  CA  . GLN D 1 428 ? -35.337 12.194  -17.982 1.00 40.77  ? 428 GLN D CA  1 
ATOM   13727 C  C   . GLN D 1 428 ? -36.578 11.347  -18.251 1.00 47.53  ? 428 GLN D C   1 
ATOM   13728 O  O   . GLN D 1 428 ? -37.183 10.809  -17.315 1.00 47.66  ? 428 GLN D O   1 
ATOM   13729 C  CB  . GLN D 1 428 ? -35.718 13.668  -17.880 1.00 37.86  ? 428 GLN D CB  1 
ATOM   13730 C  CG  . GLN D 1 428 ? -34.646 14.543  -17.298 1.00 37.51  ? 428 GLN D CG  1 
ATOM   13731 C  CD  . GLN D 1 428 ? -35.063 15.999  -17.207 1.00 42.84  ? 428 GLN D CD  1 
ATOM   13732 O  OE1 . GLN D 1 428 ? -34.519 16.863  -17.899 1.00 43.97  ? 428 GLN D OE1 1 
ATOM   13733 N  NE2 . GLN D 1 428 ? -36.023 16.285  -16.330 1.00 40.33  ? 428 GLN D NE2 1 
ATOM   13734 N  N   . ILE D 1 429 ? -36.983 11.225  -19.518 1.00 43.09  ? 429 ILE D N   1 
ATOM   13735 C  CA  . ILE D 1 429 ? -38.124 10.372  -19.847 1.00 44.52  ? 429 ILE D CA  1 
ATOM   13736 C  C   . ILE D 1 429 ? -37.780 8.915   -19.597 1.00 48.25  ? 429 ILE D C   1 
ATOM   13737 O  O   . ILE D 1 429 ? -38.570 8.161   -19.014 1.00 52.89  ? 429 ILE D O   1 
ATOM   13738 C  CB  . ILE D 1 429 ? -38.578 10.595  -21.304 1.00 47.63  ? 429 ILE D CB  1 
ATOM   13739 C  CG1 . ILE D 1 429 ? -39.524 11.798  -21.397 1.00 47.15  ? 429 ILE D CG1 1 
ATOM   13740 C  CG2 . ILE D 1 429 ? -39.236 9.339   -21.867 1.00 40.87  ? 429 ILE D CG2 1 
ATOM   13741 C  CD1 . ILE D 1 429 ? -39.526 12.473  -22.768 1.00 45.08  ? 429 ILE D CD1 1 
ATOM   13742 N  N   . ALA D 1 430 ? -36.603 8.487   -20.048 1.00 44.94  ? 430 ALA D N   1 
ATOM   13743 C  CA  . ALA D 1 430 ? -36.145 7.144   -19.718 1.00 40.68  ? 430 ALA D CA  1 
ATOM   13744 C  C   . ALA D 1 430 ? -36.165 6.906   -18.214 1.00 46.73  ? 430 ALA D C   1 
ATOM   13745 O  O   . ALA D 1 430 ? -36.404 5.778   -17.760 1.00 43.38  ? 430 ALA D O   1 
ATOM   13746 C  CB  . ALA D 1 430 ? -34.738 6.913   -20.282 1.00 43.51  ? 430 ALA D CB  1 
ATOM   13747 N  N   . ASP D 1 431 ? -35.950 7.963   -17.425 1.00 51.11  ? 431 ASP D N   1 
ATOM   13748 C  CA  . ASP D 1 431 ? -35.965 7.824   -15.973 1.00 48.11  ? 431 ASP D CA  1 
ATOM   13749 C  C   . ASP D 1 431 ? -37.391 7.634   -15.448 1.00 50.56  ? 431 ASP D C   1 
ATOM   13750 O  O   . ASP D 1 431 ? -37.641 6.744   -14.628 1.00 53.59  ? 431 ASP D O   1 
ATOM   13751 C  CB  . ASP D 1 431 ? -35.291 9.037   -15.327 1.00 42.50  ? 431 ASP D CB  1 
ATOM   13752 C  CG  . ASP D 1 431 ? -33.789 8.838   -15.122 1.00 46.84  ? 431 ASP D CG  1 
ATOM   13753 O  OD1 . ASP D 1 431 ? -33.225 7.849   -15.648 1.00 45.10  ? 431 ASP D OD1 1 
ATOM   13754 O  OD2 . ASP D 1 431 ? -33.168 9.678   -14.436 1.00 43.12  ? 431 ASP D OD2 1 
ATOM   13755 N  N   . ARG D 1 432 ? -38.344 8.453   -15.911 1.00 46.45  ? 432 ARG D N   1 
ATOM   13756 C  CA  . ARG D 1 432 ? -39.730 8.275   -15.479 1.00 55.33  ? 432 ARG D CA  1 
ATOM   13757 C  C   . ARG D 1 432 ? -40.354 6.984   -15.992 1.00 51.24  ? 432 ARG D C   1 
ATOM   13758 O  O   . ARG D 1 432 ? -41.314 6.498   -15.389 1.00 58.29  ? 432 ARG D O   1 
ATOM   13759 C  CB  . ARG D 1 432 ? -40.611 9.442   -15.926 1.00 59.01  ? 432 ARG D CB  1 
ATOM   13760 C  CG  . ARG D 1 432 ? -40.006 10.822  -15.795 1.00 58.60  ? 432 ARG D CG  1 
ATOM   13761 C  CD  . ARG D 1 432 ? -40.799 11.796  -16.662 1.00 62.57  ? 432 ARG D CD  1 
ATOM   13762 N  NE  . ARG D 1 432 ? -42.182 11.355  -16.832 1.00 62.81  ? 432 ARG D NE  1 
ATOM   13763 C  CZ  . ARG D 1 432 ? -42.865 11.450  -17.965 1.00 62.35  ? 432 ARG D CZ  1 
ATOM   13764 N  NH1 . ARG D 1 432 ? -42.340 12.011  -19.044 1.00 60.30  ? 432 ARG D NH1 1 
ATOM   13765 N  NH2 . ARG D 1 432 ? -44.110 10.980  -18.014 1.00 63.02  ? 432 ARG D NH2 1 
ATOM   13766 N  N   . LEU D 1 433 ? -39.850 6.424   -17.091 1.00 50.02  ? 433 LEU D N   1 
ATOM   13767 C  CA  . LEU D 1 433 ? -40.405 5.173   -17.597 1.00 51.14  ? 433 LEU D CA  1 
ATOM   13768 C  C   . LEU D 1 433 ? -39.940 3.970   -16.787 1.00 51.15  ? 433 LEU D C   1 
ATOM   13769 O  O   . LEU D 1 433 ? -40.690 2.998   -16.644 1.00 51.41  ? 433 LEU D O   1 
ATOM   13770 C  CB  . LEU D 1 433 ? -40.027 4.975   -19.070 1.00 47.67  ? 433 LEU D CB  1 
ATOM   13771 C  CG  . LEU D 1 433 ? -40.839 5.638   -20.187 1.00 50.00  ? 433 LEU D CG  1 
ATOM   13772 C  CD1 . LEU D 1 433 ? -39.990 5.758   -21.425 1.00 48.07  ? 433 LEU D CD1 1 
ATOM   13773 C  CD2 . LEU D 1 433 ? -42.091 4.848   -20.506 1.00 53.06  ? 433 LEU D CD2 1 
ATOM   13774 N  N   . ALA D 1 434 ? -38.705 4.001   -16.279 1.00 53.78  ? 434 ALA D N   1 
ATOM   13775 C  CA  . ALA D 1 434 ? -38.200 2.884   -15.489 1.00 53.72  ? 434 ALA D CA  1 
ATOM   13776 C  C   . ALA D 1 434 ? -39.035 2.677   -14.232 1.00 55.67  ? 434 ALA D C   1 
ATOM   13777 O  O   . ALA D 1 434 ? -39.342 1.536   -13.862 1.00 58.48  ? 434 ALA D O   1 
ATOM   13778 C  CB  . ALA D 1 434 ? -36.738 3.125   -15.129 1.00 51.15  ? 434 ALA D CB  1 
ATOM   13779 N  N   . GLU D 1 435 ? -39.422 3.773   -13.579 1.00 56.48  ? 435 GLU D N   1 
ATOM   13780 C  CA  . GLU D 1 435 ? -40.288 3.774   -12.402 1.00 56.87  ? 435 GLU D CA  1 
ATOM   13781 C  C   . GLU D 1 435 ? -41.565 2.974   -12.599 1.00 54.44  ? 435 GLU D C   1 
ATOM   13782 O  O   . GLU D 1 435 ? -42.612 3.558   -12.869 1.00 58.01  ? 435 GLU D O   1 
ATOM   13783 C  CB  . GLU D 1 435 ? -40.655 5.210   -12.047 1.00 56.44  ? 435 GLU D CB  1 
ATOM   13784 C  CG  . GLU D 1 435 ? -39.466 6.099   -11.932 1.00 53.97  ? 435 GLU D CG  1 
ATOM   13785 C  CD  . GLU D 1 435 ? -39.828 7.464   -11.413 1.00 67.48  ? 435 GLU D CD  1 
ATOM   13786 O  OE1 . GLU D 1 435 ? -39.156 7.933   -10.470 1.00 76.22  ? 435 GLU D OE1 1 
ATOM   13787 O  OE2 . GLU D 1 435 ? -40.785 8.068   -11.943 1.00 77.73  ? 435 GLU D OE2 1 
HETATM 13788 RB RB  . RB  E 2 .   ? -1.906  -9.410  8.290   1.00 47.83  ? 501 RB  A RB  1 
HETATM 13789 RB RB  . RB  F 2 .   ? 22.363  33.518  6.378   1.00 52.15  ? 501 RB  B RB  1 
HETATM 13790 RB RB  . RB  G 2 .   ? -6.971  52.608  -32.227 1.00 53.52  ? 501 RB  C RB  1 
HETATM 13791 RB RB  . RB  H 2 .   ? -30.672 9.993   -40.051 1.00 66.68  ? 501 RB  D RB  1 
HETATM 13792 O  O   . HOH I 3 .   ? 4.421   18.780  -1.248  1.00 27.09  ? 601 HOH A O   1 
HETATM 13793 O  O   . HOH I 3 .   ? -13.656 -8.116  -3.458  1.00 33.95  ? 602 HOH A O   1 
HETATM 13794 O  O   . HOH I 3 .   ? -19.595 12.502  9.073   1.00 33.96  ? 603 HOH A O   1 
HETATM 13795 O  O   . HOH I 3 .   ? 6.657   11.681  -3.674  1.00 27.91  ? 604 HOH A O   1 
HETATM 13796 O  O   . HOH I 3 .   ? -15.450 -0.728  -0.982  1.00 30.28  ? 605 HOH A O   1 
HETATM 13797 O  O   . HOH I 3 .   ? 5.437   27.977  -3.382  1.00 21.14  ? 606 HOH A O   1 
HETATM 13798 O  O   . HOH I 3 .   ? 15.543  2.618   -4.450  1.00 34.21  ? 607 HOH A O   1 
HETATM 13799 O  O   . HOH I 3 .   ? -0.194  0.485   -13.058 1.00 34.47  ? 608 HOH A O   1 
HETATM 13800 O  O   . HOH I 3 .   ? 11.485  33.616  -15.331 1.00 29.87  ? 609 HOH A O   1 
HETATM 13801 O  O   . HOH I 3 .   ? -16.711 -2.898  23.976  1.00 30.00  ? 610 HOH A O   1 
HETATM 13802 O  O   . HOH I 3 .   ? 9.377   -11.012 1.540   1.00 29.77  ? 611 HOH A O   1 
HETATM 13803 O  O   . HOH I 3 .   ? 7.639   -4.716  -19.310 1.00 33.26  ? 612 HOH A O   1 
HETATM 13804 O  O   . HOH I 3 .   ? -7.736  -0.467  21.732  1.00 26.68  ? 613 HOH A O   1 
HETATM 13805 O  O   . HOH I 3 .   ? 0.634   -27.251 4.229   1.00 30.43  ? 614 HOH A O   1 
HETATM 13806 O  O   . HOH I 3 .   ? -1.233  -2.098  -8.617  1.00 25.95  ? 615 HOH A O   1 
HETATM 13807 O  O   . HOH I 3 .   ? -10.113 -2.076  20.485  1.00 27.28  ? 616 HOH A O   1 
HETATM 13808 O  O   . HOH I 3 .   ? -13.587 13.597  -7.268  1.00 31.84  ? 617 HOH A O   1 
HETATM 13809 O  O   . HOH I 3 .   ? 14.954  19.573  -19.559 1.00 24.73  ? 618 HOH A O   1 
HETATM 13810 O  O   . HOH I 3 .   ? 0.251   2.997   8.917   1.00 29.72  ? 619 HOH A O   1 
HETATM 13811 O  O   . HOH I 3 .   ? 4.403   2.600   -2.724  1.00 20.51  ? 620 HOH A O   1 
HETATM 13812 O  O   . HOH I 3 .   ? -3.313  -11.757 -16.186 1.00 30.58  ? 621 HOH A O   1 
HETATM 13813 O  O   . HOH I 3 .   ? -5.421  5.964   17.310  1.00 22.39  ? 622 HOH A O   1 
HETATM 13814 O  O   . HOH I 3 .   ? 20.500  14.157  -25.550 1.00 31.24  ? 623 HOH A O   1 
HETATM 13815 O  O   . HOH I 3 .   ? 4.137   18.284  -9.311  1.00 31.83  ? 624 HOH A O   1 
HETATM 13816 O  O   . HOH I 3 .   ? -2.883  -7.781  9.502   1.00 32.70  ? 625 HOH A O   1 
HETATM 13817 O  O   . HOH I 3 .   ? -7.066  -3.316  -0.123  1.00 28.89  ? 626 HOH A O   1 
HETATM 13818 O  O   . HOH I 3 .   ? -19.368 -6.427  2.252   1.00 33.17  ? 627 HOH A O   1 
HETATM 13819 O  O   . HOH I 3 .   ? 7.079   0.823   6.858   1.00 28.15  ? 628 HOH A O   1 
HETATM 13820 O  O   . HOH I 3 .   ? -11.491 -9.433  -1.573  1.00 29.37  ? 629 HOH A O   1 
HETATM 13821 O  O   . HOH I 3 .   ? -13.581 -4.887  16.811  1.00 26.52  ? 630 HOH A O   1 
HETATM 13822 O  O   . HOH I 3 .   ? -0.739  -5.760  36.774  1.00 36.14  ? 631 HOH A O   1 
HETATM 13823 O  O   . HOH I 3 .   ? 9.826   20.084  -4.687  1.00 24.80  ? 632 HOH A O   1 
HETATM 13824 O  O   . HOH I 3 .   ? -9.628  -0.601  14.323  1.00 26.96  ? 633 HOH A O   1 
HETATM 13825 O  O   . HOH I 3 .   ? 3.250   31.044  -8.851  1.00 29.95  ? 634 HOH A O   1 
HETATM 13826 O  O   . HOH I 3 .   ? 6.386   24.194  -28.076 1.00 26.41  ? 635 HOH A O   1 
HETATM 13827 O  O   . HOH I 3 .   ? -7.782  -3.990  -8.560  1.00 31.17  ? 636 HOH A O   1 
HETATM 13828 O  O   . HOH I 3 .   ? 7.671   12.029  2.544   1.00 23.82  ? 637 HOH A O   1 
HETATM 13829 O  O   . HOH I 3 .   ? -16.444 14.102  0.149   1.00 30.24  ? 638 HOH A O   1 
HETATM 13830 O  O   . HOH I 3 .   ? -0.064  -9.262  9.611   1.00 33.47  ? 639 HOH A O   1 
HETATM 13831 O  O   . HOH I 3 .   ? 6.044   26.319  -0.224  1.00 26.26  ? 640 HOH A O   1 
HETATM 13832 O  O   . HOH I 3 .   ? -21.134 18.643  4.461   1.00 44.20  ? 641 HOH A O   1 
HETATM 13833 O  O   . HOH I 3 .   ? -2.319  -25.796 6.316   1.00 31.62  ? 642 HOH A O   1 
HETATM 13834 O  O   . HOH I 3 .   ? 19.309  32.877  -9.088  1.00 31.12  ? 643 HOH A O   1 
HETATM 13835 O  O   . HOH I 3 .   ? 12.638  19.978  -1.326  1.00 23.81  ? 644 HOH A O   1 
HETATM 13836 O  O   . HOH I 3 .   ? 18.424  17.461  -0.601  1.00 30.00  ? 645 HOH A O   1 
HETATM 13837 O  O   . HOH I 3 .   ? 11.151  24.209  -27.605 1.00 28.33  ? 646 HOH A O   1 
HETATM 13838 O  O   . HOH I 3 .   ? 12.196  -1.983  11.307  1.00 34.19  ? 647 HOH A O   1 
HETATM 13839 O  O   . HOH I 3 .   ? 6.759   -2.387  -13.141 1.00 29.89  ? 648 HOH A O   1 
HETATM 13840 O  O   . HOH I 3 .   ? 18.913  8.442   -4.506  1.00 30.97  ? 649 HOH A O   1 
HETATM 13841 O  O   . HOH I 3 .   ? -22.151 -11.326 2.080   1.00 32.08  ? 650 HOH A O   1 
HETATM 13842 O  O   . HOH I 3 .   ? -10.675 -1.727  16.556  1.00 27.40  ? 651 HOH A O   1 
HETATM 13843 O  O   . HOH I 3 .   ? -11.395 -20.177 15.629  1.00 33.92  ? 652 HOH A O   1 
HETATM 13844 O  O   . HOH I 3 .   ? 13.186  -5.505  4.717   1.00 34.46  ? 653 HOH A O   1 
HETATM 13845 O  O   . HOH I 3 .   ? 13.239  20.080  -23.455 1.00 29.28  ? 654 HOH A O   1 
HETATM 13846 O  O   . HOH I 3 .   ? 13.387  -0.699  -1.064  1.00 28.82  ? 655 HOH A O   1 
HETATM 13847 O  O   . HOH I 3 .   ? 9.775   34.722  -13.864 1.00 29.04  ? 656 HOH A O   1 
HETATM 13848 O  O   . HOH I 3 .   ? -18.510 12.769  12.904  1.00 32.18  ? 657 HOH A O   1 
HETATM 13849 O  O   . HOH I 3 .   ? -3.246  -13.237 16.493  1.00 37.65  ? 658 HOH A O   1 
HETATM 13850 O  O   . HOH I 3 .   ? 4.461   22.626  -10.097 1.00 25.43  ? 659 HOH A O   1 
HETATM 13851 O  O   . HOH I 3 .   ? 1.655   -14.582 8.583   1.00 31.94  ? 660 HOH A O   1 
HETATM 13852 O  O   . HOH I 3 .   ? 3.585   3.870   -4.927  1.00 19.97  ? 661 HOH A O   1 
HETATM 13853 O  O   . HOH I 3 .   ? 21.472  4.720   -14.019 1.00 33.41  ? 662 HOH A O   1 
HETATM 13854 O  O   . HOH I 3 .   ? 4.851   20.105  -11.297 1.00 25.26  ? 663 HOH A O   1 
HETATM 13855 O  O   . HOH I 3 .   ? 14.330  24.873  2.641   1.00 30.53  ? 664 HOH A O   1 
HETATM 13856 O  O   . HOH I 3 .   ? -11.239 8.481   21.655  1.00 28.02  ? 665 HOH A O   1 
HETATM 13857 O  O   . HOH I 3 .   ? 18.138  3.218   -4.955  1.00 35.18  ? 666 HOH A O   1 
HETATM 13858 O  O   . HOH I 3 .   ? 20.126  32.536  -0.130  1.00 34.30  ? 667 HOH A O   1 
HETATM 13859 O  O   . HOH I 3 .   ? 18.254  28.901  -4.588  1.00 28.42  ? 668 HOH A O   1 
HETATM 13860 O  O   . HOH I 3 .   ? 5.624   -13.780 6.900   1.00 28.77  ? 669 HOH A O   1 
HETATM 13861 O  O   . HOH I 3 .   ? -3.872  -4.026  7.736   1.00 27.12  ? 670 HOH A O   1 
HETATM 13862 O  O   . HOH I 3 .   ? 3.909   2.682   -16.336 1.00 26.81  ? 671 HOH A O   1 
HETATM 13863 O  O   . HOH I 3 .   ? 14.441  21.701  0.031   1.00 30.42  ? 672 HOH A O   1 
HETATM 13864 O  O   . HOH I 3 .   ? -20.674 -11.616 30.649  1.00 32.36  ? 673 HOH A O   1 
HETATM 13865 O  O   . HOH I 3 .   ? 6.559   11.389  0.178   1.00 30.93  ? 674 HOH A O   1 
HETATM 13866 O  O   . HOH I 3 .   ? 9.468   31.712  -15.504 1.00 30.00  ? 675 HOH A O   1 
HETATM 13867 O  O   . HOH I 3 .   ? -11.151 13.593  13.167  1.00 27.89  ? 676 HOH A O   1 
HETATM 13868 O  O   . HOH I 3 .   ? -1.267  9.573   -7.670  1.00 30.00  ? 677 HOH A O   1 
HETATM 13869 O  O   . HOH I 3 .   ? 3.014   9.696   -2.734  1.00 20.20  ? 678 HOH A O   1 
HETATM 13870 O  O   . HOH I 3 .   ? -5.658  -3.227  33.180  1.00 32.67  ? 679 HOH A O   1 
HETATM 13871 O  O   . HOH I 3 .   ? 4.286   17.305  -6.003  1.00 24.85  ? 680 HOH A O   1 
HETATM 13872 O  O   . HOH I 3 .   ? -5.174  11.189  -25.183 1.00 35.75  ? 681 HOH A O   1 
HETATM 13873 O  O   . HOH I 3 .   ? 9.726   29.848  -17.371 1.00 25.74  ? 682 HOH A O   1 
HETATM 13874 O  O   . HOH I 3 .   ? 10.506  1.272   -25.874 1.00 35.24  ? 683 HOH A O   1 
HETATM 13875 O  O   . HOH I 3 .   ? -11.632 -4.150  22.015  1.00 25.31  ? 684 HOH A O   1 
HETATM 13876 O  O   . HOH I 3 .   ? 1.920   13.183  -12.828 1.00 34.05  ? 685 HOH A O   1 
HETATM 13877 O  O   . HOH I 3 .   ? -5.683  11.812  8.228   1.00 26.80  ? 686 HOH A O   1 
HETATM 13878 O  O   . HOH I 3 .   ? 7.668   -3.294  12.292  1.00 32.41  ? 687 HOH A O   1 
HETATM 13879 O  O   . HOH I 3 .   ? 18.678  11.822  -3.413  1.00 35.62  ? 688 HOH A O   1 
HETATM 13880 O  O   . HOH I 3 .   ? -3.933  14.310  4.248   1.00 23.99  ? 689 HOH A O   1 
HETATM 13881 O  O   . HOH I 3 .   ? 1.273   12.313  13.577  1.00 26.34  ? 690 HOH A O   1 
HETATM 13882 O  O   . HOH I 3 .   ? 25.566  21.031  -5.302  1.00 39.37  ? 691 HOH A O   1 
HETATM 13883 O  O   . HOH I 3 .   ? 1.740   12.641  -6.505  1.00 20.58  ? 692 HOH A O   1 
HETATM 13884 O  O   . HOH I 3 .   ? 2.558   12.124  -3.878  1.00 30.00  ? 693 HOH A O   1 
HETATM 13885 O  O   . HOH I 3 .   ? 7.635   28.717  -18.990 1.00 30.00  ? 694 HOH A O   1 
HETATM 13886 O  O   . HOH I 3 .   ? 3.270   23.911  -25.420 1.00 36.03  ? 695 HOH A O   1 
HETATM 13887 O  O   . HOH I 3 .   ? -9.145  14.942  12.201  1.00 25.71  ? 696 HOH A O   1 
HETATM 13888 O  O   . HOH I 3 .   ? -3.919  -25.651 22.208  1.00 50.19  ? 697 HOH A O   1 
HETATM 13889 O  O   . HOH I 3 .   ? -3.737  10.104  11.503  1.00 26.14  ? 698 HOH A O   1 
HETATM 13890 O  O   . HOH I 3 .   ? -12.749 18.955  14.591  1.00 36.03  ? 699 HOH A O   1 
HETATM 13891 O  O   . HOH J 3 .   ? 13.223  40.446  -3.425  1.00 23.55  ? 601 HOH B O   1 
HETATM 13892 O  O   . HOH J 3 .   ? 12.266  36.295  -3.417  1.00 29.23  ? 602 HOH B O   1 
HETATM 13893 O  O   . HOH J 3 .   ? -8.411  7.998   18.947  1.00 24.49  ? 603 HOH B O   1 
HETATM 13894 O  O   . HOH J 3 .   ? -9.852  0.750   29.030  1.00 27.77  ? 604 HOH B O   1 
HETATM 13895 O  O   . HOH J 3 .   ? 28.838  24.863  14.283  1.00 29.83  ? 605 HOH B O   1 
HETATM 13896 O  O   . HOH J 3 .   ? 10.067  27.022  27.153  1.00 34.15  ? 606 HOH B O   1 
HETATM 13897 O  O   . HOH J 3 .   ? 18.607  23.280  28.026  1.00 29.84  ? 607 HOH B O   1 
HETATM 13898 O  O   . HOH J 3 .   ? 17.876  17.589  9.687   1.00 31.21  ? 608 HOH B O   1 
HETATM 13899 O  O   . HOH J 3 .   ? 12.472  22.523  19.490  1.00 24.30  ? 609 HOH B O   1 
HETATM 13900 O  O   . HOH J 3 .   ? -6.971  8.444   16.716  1.00 27.39  ? 610 HOH B O   1 
HETATM 13901 O  O   . HOH J 3 .   ? 8.352   28.368  -3.849  1.00 21.71  ? 611 HOH B O   1 
HETATM 13902 O  O   . HOH J 3 .   ? -5.668  10.590  41.505  1.00 24.21  ? 612 HOH B O   1 
HETATM 13903 O  O   . HOH J 3 .   ? -4.679  -5.670  23.345  1.00 29.63  ? 613 HOH B O   1 
HETATM 13904 O  O   . HOH J 3 .   ? -4.857  35.777  -1.131  1.00 30.90  ? 614 HOH B O   1 
HETATM 13905 O  O   . HOH J 3 .   ? 7.568   15.911  17.677  1.00 25.68  ? 615 HOH B O   1 
HETATM 13906 O  O   . HOH J 3 .   ? -5.513  15.961  34.134  1.00 31.74  ? 616 HOH B O   1 
HETATM 13907 O  O   . HOH J 3 .   ? 9.886   15.544  24.117  1.00 18.74  ? 617 HOH B O   1 
HETATM 13908 O  O   . HOH J 3 .   ? 16.730  20.005  0.304   1.00 31.64  ? 618 HOH B O   1 
HETATM 13909 O  O   . HOH J 3 .   ? -1.391  -2.884  19.138  1.00 30.13  ? 619 HOH B O   1 
HETATM 13910 O  O   . HOH J 3 .   ? 16.677  16.279  16.351  1.00 25.28  ? 620 HOH B O   1 
HETATM 13911 O  O   . HOH J 3 .   ? -9.664  38.068  1.883   1.00 36.65  ? 621 HOH B O   1 
HETATM 13912 O  O   . HOH J 3 .   ? 11.406  35.237  -0.890  1.00 23.68  ? 622 HOH B O   1 
HETATM 13913 O  O   . HOH J 3 .   ? -3.305  6.829   41.329  1.00 26.33  ? 623 HOH B O   1 
HETATM 13914 O  O   . HOH J 3 .   ? 20.710  32.987  4.903   1.00 35.76  ? 624 HOH B O   1 
HETATM 13915 O  O   . HOH J 3 .   ? 14.024  43.394  16.724  1.00 42.92  ? 625 HOH B O   1 
HETATM 13916 O  O   . HOH J 3 .   ? -10.701 14.736  26.525  1.00 23.67  ? 626 HOH B O   1 
HETATM 13917 O  O   . HOH J 3 .   ? 16.889  32.175  6.520   1.00 27.00  ? 627 HOH B O   1 
HETATM 13918 O  O   . HOH J 3 .   ? 13.007  25.126  5.167   1.00 30.00  ? 628 HOH B O   1 
HETATM 13919 O  O   . HOH J 3 .   ? -13.415 3.017   34.836  1.00 25.88  ? 629 HOH B O   1 
HETATM 13920 O  O   . HOH J 3 .   ? -3.905  32.882  -4.189  1.00 27.93  ? 630 HOH B O   1 
HETATM 13921 O  O   . HOH J 3 .   ? 1.045   9.860   14.298  1.00 30.00  ? 631 HOH B O   1 
HETATM 13922 O  O   . HOH J 3 .   ? 15.115  8.670   40.348  1.00 36.87  ? 632 HOH B O   1 
HETATM 13923 O  O   . HOH J 3 .   ? 0.135   38.501  -4.588  1.00 27.87  ? 633 HOH B O   1 
HETATM 13924 O  O   . HOH J 3 .   ? 8.448   14.604  11.820  1.00 24.20  ? 634 HOH B O   1 
HETATM 13925 O  O   . HOH J 3 .   ? 11.550  3.799   12.135  1.00 29.05  ? 635 HOH B O   1 
HETATM 13926 O  O   . HOH J 3 .   ? 13.539  35.007  13.890  1.00 24.95  ? 636 HOH B O   1 
HETATM 13927 O  O   . HOH J 3 .   ? 14.316  22.470  17.102  1.00 20.38  ? 637 HOH B O   1 
HETATM 13928 O  O   . HOH J 3 .   ? 12.526  28.212  27.165  1.00 33.79  ? 638 HOH B O   1 
HETATM 13929 O  O   . HOH J 3 .   ? 15.311  41.265  -18.406 1.00 34.97  ? 639 HOH B O   1 
HETATM 13930 O  O   . HOH J 3 .   ? 4.031   6.150   15.487  1.00 25.37  ? 640 HOH B O   1 
HETATM 13931 O  O   . HOH J 3 .   ? -0.724  29.085  7.011   1.00 30.74  ? 641 HOH B O   1 
HETATM 13932 O  O   . HOH J 3 .   ? 6.030   23.693  30.565  1.00 30.19  ? 642 HOH B O   1 
HETATM 13933 O  O   . HOH J 3 .   ? -8.499  11.868  28.629  1.00 28.22  ? 643 HOH B O   1 
HETATM 13934 O  O   . HOH J 3 .   ? 1.444   14.850  19.603  1.00 26.19  ? 644 HOH B O   1 
HETATM 13935 O  O   . HOH J 3 .   ? 3.696   5.370   34.108  1.00 24.29  ? 645 HOH B O   1 
HETATM 13936 O  O   . HOH J 3 .   ? 12.898  23.499  30.801  1.00 28.17  ? 646 HOH B O   1 
HETATM 13937 O  O   . HOH J 3 .   ? 8.622   17.816  16.370  1.00 31.84  ? 647 HOH B O   1 
HETATM 13938 O  O   . HOH J 3 .   ? -3.533  27.308  15.264  1.00 27.46  ? 648 HOH B O   1 
HETATM 13939 O  O   . HOH J 3 .   ? 4.535   -2.997  18.128  1.00 36.17  ? 649 HOH B O   1 
HETATM 13940 O  O   . HOH J 3 .   ? 13.147  33.118  -8.317  1.00 19.57  ? 650 HOH B O   1 
HETATM 13941 O  O   . HOH J 3 .   ? -7.453  4.476   30.993  1.00 23.85  ? 651 HOH B O   1 
HETATM 13942 O  O   . HOH J 3 .   ? 1.910   8.857   18.652  1.00 23.46  ? 652 HOH B O   1 
HETATM 13943 O  O   . HOH J 3 .   ? -6.200  34.292  11.455  1.00 31.60  ? 653 HOH B O   1 
HETATM 13944 O  O   . HOH J 3 .   ? -11.016 9.840   31.997  1.00 27.94  ? 654 HOH B O   1 
HETATM 13945 O  O   . HOH J 3 .   ? 3.663   3.499   14.489  1.00 24.51  ? 655 HOH B O   1 
HETATM 13946 O  O   . HOH J 3 .   ? 10.956  4.049   40.947  1.00 28.72  ? 656 HOH B O   1 
HETATM 13947 O  O   . HOH J 3 .   ? 5.167   23.966  21.200  1.00 22.18  ? 657 HOH B O   1 
HETATM 13948 O  O   . HOH J 3 .   ? 17.236  38.497  32.385  1.00 31.34  ? 658 HOH B O   1 
HETATM 13949 O  O   . HOH J 3 .   ? 24.290  17.473  30.291  1.00 34.14  ? 659 HOH B O   1 
HETATM 13950 O  O   . HOH J 3 .   ? 1.744   6.891   37.615  1.00 27.25  ? 660 HOH B O   1 
HETATM 13951 O  O   . HOH J 3 .   ? -3.461  12.179  23.632  1.00 25.01  ? 661 HOH B O   1 
HETATM 13952 O  O   . HOH J 3 .   ? -4.924  31.480  16.797  1.00 30.00  ? 662 HOH B O   1 
HETATM 13953 O  O   . HOH J 3 .   ? 19.603  45.951  18.927  1.00 32.89  ? 663 HOH B O   1 
HETATM 13954 O  O   . HOH J 3 .   ? 19.741  12.744  19.616  1.00 32.95  ? 664 HOH B O   1 
HETATM 13955 O  O   . HOH J 3 .   ? 2.085   25.812  4.801   1.00 27.19  ? 665 HOH B O   1 
HETATM 13956 O  O   . HOH J 3 .   ? 1.869   16.373  22.442  1.00 26.34  ? 666 HOH B O   1 
HETATM 13957 O  O   . HOH J 3 .   ? 18.279  37.939  -16.107 1.00 30.66  ? 667 HOH B O   1 
HETATM 13958 O  O   . HOH J 3 .   ? -1.553  32.272  -8.086  1.00 28.83  ? 668 HOH B O   1 
HETATM 13959 O  O   . HOH J 3 .   ? -1.103  13.235  24.778  1.00 27.42  ? 669 HOH B O   1 
HETATM 13960 O  O   . HOH J 3 .   ? 21.892  48.823  23.986  1.00 33.98  ? 670 HOH B O   1 
HETATM 13961 O  O   . HOH J 3 .   ? 33.346  30.968  7.243   1.00 41.11  ? 671 HOH B O   1 
HETATM 13962 O  O   . HOH J 3 .   ? 5.095   29.005  -5.939  1.00 24.89  ? 672 HOH B O   1 
HETATM 13963 O  O   . HOH J 3 .   ? 3.404   16.670  31.680  1.00 25.65  ? 673 HOH B O   1 
HETATM 13964 O  O   . HOH J 3 .   ? 15.890  38.894  -16.624 1.00 34.92  ? 674 HOH B O   1 
HETATM 13965 O  O   . HOH J 3 .   ? 15.105  6.203   14.887  1.00 30.00  ? 675 HOH B O   1 
HETATM 13966 O  O   . HOH J 3 .   ? 12.991  36.091  22.554  1.00 25.70  ? 676 HOH B O   1 
HETATM 13967 O  O   . HOH J 3 .   ? 36.129  42.057  8.838   1.00 36.08  ? 677 HOH B O   1 
HETATM 13968 O  O   . HOH J 3 .   ? -1.309  29.330  -0.719  1.00 21.13  ? 678 HOH B O   1 
HETATM 13969 O  O   . HOH J 3 .   ? 13.166  36.282  -7.133  1.00 31.12  ? 679 HOH B O   1 
HETATM 13970 O  O   . HOH J 3 .   ? 31.111  36.855  33.668  1.00 46.07  ? 680 HOH B O   1 
HETATM 13971 O  O   . HOH J 3 .   ? 14.215  38.289  -8.403  1.00 31.61  ? 681 HOH B O   1 
HETATM 13972 O  O   . HOH J 3 .   ? 8.183   16.222  13.782  1.00 26.29  ? 682 HOH B O   1 
HETATM 13973 O  O   . HOH J 3 .   ? 20.643  10.387  20.595  1.00 36.05  ? 683 HOH B O   1 
HETATM 13974 O  O   . HOH J 3 .   ? 13.370  5.125   18.790  1.00 26.66  ? 684 HOH B O   1 
HETATM 13975 O  O   . HOH J 3 .   ? -2.547  -6.640  14.214  1.00 29.73  ? 685 HOH B O   1 
HETATM 13976 O  O   . HOH J 3 .   ? -12.935 7.059   22.999  1.00 37.31  ? 686 HOH B O   1 
HETATM 13977 O  O   . HOH J 3 .   ? 17.362  32.059  -19.280 1.00 30.84  ? 687 HOH B O   1 
HETATM 13978 O  O   . HOH J 3 .   ? 7.476   19.937  16.649  1.00 28.70  ? 688 HOH B O   1 
HETATM 13979 O  O   . HOH J 3 .   ? 22.269  21.862  2.900   1.00 31.74  ? 689 HOH B O   1 
HETATM 13980 O  O   . HOH J 3 .   ? 0.872   23.172  8.819   1.00 22.09  ? 690 HOH B O   1 
HETATM 13981 O  O   . HOH J 3 .   ? -1.858  36.347  -3.047  1.00 31.72  ? 691 HOH B O   1 
HETATM 13982 O  O   . HOH J 3 .   ? 1.097   2.491   11.530  1.00 26.59  ? 692 HOH B O   1 
HETATM 13983 O  O   . HOH J 3 .   ? 1.384   15.875  17.207  1.00 30.00  ? 693 HOH B O   1 
HETATM 13984 O  O   . HOH J 3 .   ? 1.389   16.988  6.914   1.00 30.00  ? 694 HOH B O   1 
HETATM 13985 O  O   . HOH J 3 .   ? 0.548   4.277   39.479  1.00 31.15  ? 695 HOH B O   1 
HETATM 13986 O  O   . HOH J 3 .   ? 19.360  31.542  2.307   1.00 37.15  ? 696 HOH B O   1 
HETATM 13987 O  O   . HOH J 3 .   ? -4.452  15.889  16.902  1.00 30.00  ? 697 HOH B O   1 
HETATM 13988 O  O   . HOH J 3 .   ? -6.640  29.155  16.625  1.00 32.92  ? 698 HOH B O   1 
HETATM 13989 O  O   . HOH J 3 .   ? -7.835  6.590   32.478  1.00 21.07  ? 699 HOH B O   1 
HETATM 13990 O  O   . HOH J 3 .   ? 3.696   19.677  20.131  1.00 31.53  ? 700 HOH B O   1 
HETATM 13991 O  O   . HOH J 3 .   ? 5.248   24.857  1.530   1.00 21.70  ? 701 HOH B O   1 
HETATM 13992 O  O   . HOH J 3 .   ? -1.645  26.849  0.576   1.00 29.11  ? 702 HOH B O   1 
HETATM 13993 O  O   . HOH J 3 .   ? 8.827   42.514  -13.211 1.00 29.10  ? 703 HOH B O   1 
HETATM 13994 O  O   . HOH J 3 .   ? 3.322   22.317  21.054  1.00 30.68  ? 704 HOH B O   1 
HETATM 13995 O  O   . HOH K 3 .   ? 5.943   51.066  -41.990 1.00 30.00  ? 601 HOH C O   1 
HETATM 13996 O  O   . HOH K 3 .   ? -8.707  70.496  -35.774 1.00 37.18  ? 602 HOH C O   1 
HETATM 13997 O  O   . HOH K 3 .   ? -15.471 31.458  -40.559 1.00 26.00  ? 603 HOH C O   1 
HETATM 13998 O  O   . HOH K 3 .   ? -6.669  34.689  -51.369 1.00 29.05  ? 604 HOH C O   1 
HETATM 13999 O  O   . HOH K 3 .   ? -13.426 32.243  -46.641 1.00 27.81  ? 605 HOH C O   1 
HETATM 14000 O  O   . HOH K 3 .   ? -18.224 40.836  -37.606 1.00 31.94  ? 606 HOH C O   1 
HETATM 14001 O  O   . HOH K 3 .   ? -8.817  51.762  -31.155 1.00 33.28  ? 607 HOH C O   1 
HETATM 14002 O  O   . HOH K 3 .   ? 0.397   30.292  -18.675 1.00 38.74  ? 608 HOH C O   1 
HETATM 14003 O  O   . HOH K 3 .   ? 0.539   44.550  -22.788 1.00 34.32  ? 609 HOH C O   1 
HETATM 14004 O  O   . HOH K 3 .   ? 1.639   30.916  -34.443 1.00 32.19  ? 610 HOH C O   1 
HETATM 14005 O  O   . HOH K 3 .   ? 8.911   30.112  -25.978 1.00 29.89  ? 611 HOH C O   1 
HETATM 14006 O  O   . HOH K 3 .   ? -19.066 41.625  -29.736 1.00 38.29  ? 612 HOH C O   1 
HETATM 14007 O  O   . HOH K 3 .   ? -25.166 11.352  -54.779 1.00 31.75  ? 613 HOH C O   1 
HETATM 14008 O  O   . HOH K 3 .   ? -16.516 23.705  -48.286 1.00 26.63  ? 614 HOH C O   1 
HETATM 14009 O  O   . HOH K 3 .   ? 8.221   44.993  -38.797 1.00 30.00  ? 615 HOH C O   1 
HETATM 14010 O  O   . HOH K 3 .   ? -0.397  43.137  -25.412 1.00 33.63  ? 616 HOH C O   1 
HETATM 14011 O  O   . HOH K 3 .   ? -15.550 42.356  -35.427 1.00 32.08  ? 617 HOH C O   1 
HETATM 14012 O  O   . HOH K 3 .   ? -13.740 43.507  -68.509 1.00 31.39  ? 618 HOH C O   1 
HETATM 14013 O  O   . HOH K 3 .   ? 4.749   25.748  -38.076 1.00 33.74  ? 619 HOH C O   1 
HETATM 14014 O  O   . HOH K 3 .   ? -1.915  54.523  -26.593 1.00 29.88  ? 620 HOH C O   1 
HETATM 14015 O  O   . HOH K 3 .   ? -5.269  34.814  -48.751 1.00 26.14  ? 621 HOH C O   1 
HETATM 14016 O  O   . HOH K 3 .   ? -8.210  14.790  -62.298 1.00 26.94  ? 622 HOH C O   1 
HETATM 14017 O  O   . HOH K 3 .   ? 8.977   29.292  -38.439 1.00 33.30  ? 623 HOH C O   1 
HETATM 14018 O  O   . HOH K 3 .   ? 3.317   29.811  -19.412 1.00 26.52  ? 624 HOH C O   1 
HETATM 14019 O  O   . HOH K 3 .   ? -7.706  20.920  -47.518 1.00 29.21  ? 625 HOH C O   1 
HETATM 14020 O  O   . HOH K 3 .   ? -16.506 10.912  -59.781 1.00 30.40  ? 626 HOH C O   1 
HETATM 14021 O  O   . HOH K 3 .   ? -8.039  17.626  -58.671 1.00 25.90  ? 627 HOH C O   1 
HETATM 14022 O  O   . HOH K 3 .   ? -5.874  31.108  -33.937 1.00 31.48  ? 628 HOH C O   1 
HETATM 14023 O  O   . HOH K 3 .   ? -13.300 17.332  -43.631 1.00 25.17  ? 629 HOH C O   1 
HETATM 14024 O  O   . HOH K 3 .   ? -4.813  46.411  -49.327 1.00 24.05  ? 630 HOH C O   1 
HETATM 14025 O  O   . HOH K 3 .   ? -10.476 21.562  -53.040 1.00 26.76  ? 631 HOH C O   1 
HETATM 14026 O  O   . HOH K 3 .   ? 5.595   28.760  -23.270 1.00 32.16  ? 632 HOH C O   1 
HETATM 14027 O  O   . HOH K 3 .   ? -0.672  46.621  -40.076 1.00 30.26  ? 633 HOH C O   1 
HETATM 14028 O  O   . HOH K 3 .   ? -17.182 24.550  -67.164 1.00 26.39  ? 634 HOH C O   1 
HETATM 14029 O  O   . HOH K 3 .   ? 1.170   47.789  -48.153 1.00 30.33  ? 635 HOH C O   1 
HETATM 14030 O  O   . HOH K 3 .   ? -14.309 20.935  -71.423 1.00 35.53  ? 636 HOH C O   1 
HETATM 14031 O  O   . HOH K 3 .   ? -24.988 14.520  -49.984 1.00 36.78  ? 637 HOH C O   1 
HETATM 14032 O  O   . HOH K 3 .   ? -21.317 45.532  -31.892 1.00 33.22  ? 638 HOH C O   1 
HETATM 14033 O  O   . HOH K 3 .   ? -19.213 11.482  -53.216 1.00 26.26  ? 639 HOH C O   1 
HETATM 14034 O  O   . HOH K 3 .   ? -9.658  20.982  -71.133 1.00 25.69  ? 640 HOH C O   1 
HETATM 14035 O  O   . HOH K 3 .   ? -9.837  33.887  -44.599 1.00 23.84  ? 641 HOH C O   1 
HETATM 14036 O  O   . HOH K 3 .   ? -22.334 22.001  -44.640 1.00 26.11  ? 642 HOH C O   1 
HETATM 14037 O  O   . HOH K 3 .   ? -12.701 47.573  -4.279  1.00 33.03  ? 643 HOH C O   1 
HETATM 14038 O  O   . HOH K 3 .   ? -12.266 9.569   -66.125 1.00 29.82  ? 644 HOH C O   1 
HETATM 14039 O  O   . HOH K 3 .   ? -8.735  42.038  -58.024 1.00 23.32  ? 645 HOH C O   1 
HETATM 14040 O  O   . HOH K 3 .   ? -10.481 39.708  -46.727 1.00 26.50  ? 646 HOH C O   1 
HETATM 14041 O  O   . HOH K 3 .   ? -15.658 10.878  -53.325 1.00 27.64  ? 647 HOH C O   1 
HETATM 14042 O  O   . HOH K 3 .   ? -14.558 14.732  -61.461 1.00 27.77  ? 648 HOH C O   1 
HETATM 14043 O  O   . HOH K 3 .   ? -19.342 25.291  -64.009 1.00 27.18  ? 649 HOH C O   1 
HETATM 14044 O  O   . HOH K 3 .   ? -10.627 58.029  -32.282 1.00 30.00  ? 650 HOH C O   1 
HETATM 14045 O  O   . HOH K 3 .   ? 6.072   29.451  -44.576 1.00 30.00  ? 651 HOH C O   1 
HETATM 14046 O  O   . HOH K 3 .   ? -22.112 18.534  -42.193 1.00 25.71  ? 652 HOH C O   1 
HETATM 14047 O  O   . HOH K 3 .   ? -11.206 27.923  -60.827 1.00 29.63  ? 653 HOH C O   1 
HETATM 14048 O  O   . HOH K 3 .   ? -9.553  30.492  -60.328 1.00 26.99  ? 654 HOH C O   1 
HETATM 14049 O  O   . HOH K 3 .   ? -4.846  36.515  -23.543 1.00 26.10  ? 655 HOH C O   1 
HETATM 14050 O  O   . HOH K 3 .   ? -24.222 31.360  -70.391 1.00 30.00  ? 656 HOH C O   1 
HETATM 14051 O  O   . HOH K 3 .   ? -3.495  42.907  -18.142 1.00 24.23  ? 657 HOH C O   1 
HETATM 14052 O  O   . HOH K 3 .   ? 5.697   58.597  -43.172 1.00 35.43  ? 658 HOH C O   1 
HETATM 14053 O  O   . HOH K 3 .   ? -11.851 5.545   -63.249 1.00 37.96  ? 659 HOH C O   1 
HETATM 14054 O  O   . HOH K 3 .   ? -10.891 26.993  -48.608 1.00 26.09  ? 660 HOH C O   1 
HETATM 14055 O  O   . HOH K 3 .   ? 8.167   35.655  -21.822 1.00 22.67  ? 661 HOH C O   1 
HETATM 14056 O  O   . HOH K 3 .   ? -6.559  50.994  -30.672 1.00 36.18  ? 662 HOH C O   1 
HETATM 14057 O  O   . HOH K 3 .   ? -9.950  10.609  -53.900 1.00 32.31  ? 663 HOH C O   1 
HETATM 14058 O  O   . HOH K 3 .   ? -14.859 12.896  -59.625 1.00 33.83  ? 664 HOH C O   1 
HETATM 14059 O  O   . HOH K 3 .   ? 7.798   53.944  -7.106  1.00 37.00  ? 665 HOH C O   1 
HETATM 14060 O  O   . HOH K 3 .   ? 7.536   59.617  -44.636 1.00 30.00  ? 666 HOH C O   1 
HETATM 14061 O  O   . HOH K 3 .   ? -11.117 41.209  -44.681 1.00 21.60  ? 667 HOH C O   1 
HETATM 14062 O  O   . HOH K 3 .   ? -26.924 46.802  -55.059 1.00 39.48  ? 668 HOH C O   1 
HETATM 14063 O  O   . HOH K 3 .   ? -4.681  50.246  -19.667 1.00 29.62  ? 669 HOH C O   1 
HETATM 14064 O  O   . HOH K 3 .   ? -25.553 31.557  -48.018 1.00 31.22  ? 670 HOH C O   1 
HETATM 14065 O  O   . HOH K 3 .   ? -3.169  31.195  -32.814 1.00 23.89  ? 671 HOH C O   1 
HETATM 14066 O  O   . HOH K 3 .   ? -25.601 30.410  -44.289 1.00 29.88  ? 672 HOH C O   1 
HETATM 14067 O  O   . HOH K 3 .   ? -9.734  27.707  -51.276 1.00 32.75  ? 673 HOH C O   1 
HETATM 14068 O  O   . HOH K 3 .   ? 0.359   46.276  -17.492 1.00 30.00  ? 674 HOH C O   1 
HETATM 14069 O  O   . HOH K 3 .   ? -4.395  29.191  -36.819 1.00 27.60  ? 675 HOH C O   1 
HETATM 14070 O  O   . HOH K 3 .   ? -31.723 23.331  -51.147 1.00 43.09  ? 676 HOH C O   1 
HETATM 14071 O  O   . HOH K 3 .   ? -24.386 36.163  -72.139 1.00 41.07  ? 677 HOH C O   1 
HETATM 14072 O  O   . HOH K 3 .   ? -8.386  28.975  -49.096 1.00 30.00  ? 678 HOH C O   1 
HETATM 14073 O  O   . HOH K 3 .   ? -6.265  33.484  -53.984 1.00 34.52  ? 679 HOH C O   1 
HETATM 14074 O  O   . HOH K 3 .   ? -24.254 21.462  -69.951 1.00 41.31  ? 680 HOH C O   1 
HETATM 14075 O  O   . HOH K 3 .   ? -8.342  32.647  -50.645 1.00 29.88  ? 681 HOH C O   1 
HETATM 14076 O  O   . HOH K 3 .   ? -19.268 40.615  -27.396 1.00 32.72  ? 682 HOH C O   1 
HETATM 14077 O  O   . HOH K 3 .   ? -29.412 22.946  -47.910 1.00 41.04  ? 683 HOH C O   1 
HETATM 14078 O  O   . HOH K 3 .   ? -7.961  31.466  -48.417 1.00 30.07  ? 684 HOH C O   1 
HETATM 14079 O  O   . HOH L 3 .   ? -24.254 -0.391  -29.165 1.00 39.57  ? 601 HOH D O   1 
HETATM 14080 O  O   . HOH L 3 .   ? -39.877 29.281  -54.342 1.00 30.00  ? 602 HOH D O   1 
HETATM 14081 O  O   . HOH L 3 .   ? -2.683  7.299   -43.441 1.00 30.25  ? 603 HOH D O   1 
HETATM 14082 O  O   . HOH L 3 .   ? -25.822 12.089  -22.537 1.00 30.00  ? 604 HOH D O   1 
HETATM 14083 O  O   . HOH L 3 .   ? -29.580 21.932  -3.949  1.00 37.41  ? 605 HOH D O   1 
HETATM 14084 O  O   . HOH L 3 .   ? -14.750 1.550   -62.604 1.00 31.26  ? 606 HOH D O   1 
HETATM 14085 O  O   . HOH L 3 .   ? -19.549 8.123   -51.653 1.00 30.00  ? 607 HOH D O   1 
HETATM 14086 O  O   . HOH L 3 .   ? -43.575 5.828   -15.496 1.00 40.49  ? 608 HOH D O   1 
HETATM 14087 O  O   . HOH L 3 .   ? -10.384 28.849  -27.082 1.00 25.17  ? 609 HOH D O   1 
HETATM 14088 O  O   . HOH L 3 .   ? -27.056 25.769  -43.269 1.00 30.00  ? 610 HOH D O   1 
HETATM 14089 O  O   . HOH L 3 .   ? -23.829 8.251   -71.846 1.00 41.71  ? 611 HOH D O   1 
HETATM 14090 O  O   . HOH L 3 .   ? -16.913 19.523  -19.879 1.00 36.68  ? 612 HOH D O   1 
HETATM 14091 O  O   . HOH L 3 .   ? -13.245 39.446  -27.510 1.00 28.20  ? 613 HOH D O   1 
HETATM 14092 O  O   . HOH L 3 .   ? -24.932 18.899  -13.941 1.00 31.56  ? 614 HOH D O   1 
HETATM 14093 O  O   . HOH L 3 .   ? -22.856 20.328  -24.969 1.00 32.14  ? 615 HOH D O   1 
HETATM 14094 O  O   . HOH L 3 .   ? -17.780 27.070  -25.607 1.00 27.19  ? 616 HOH D O   1 
HETATM 14095 O  O   . HOH L 3 .   ? -38.449 18.155  -32.906 1.00 36.70  ? 617 HOH D O   1 
HETATM 14096 O  O   . HOH L 3 .   ? -18.357 8.921   -45.900 1.00 31.67  ? 618 HOH D O   1 
HETATM 14097 O  O   . HOH L 3 .   ? -17.777 28.546  -31.504 1.00 26.25  ? 619 HOH D O   1 
HETATM 14098 O  O   . HOH L 3 .   ? -24.269 28.730  -27.793 1.00 30.00  ? 620 HOH D O   1 
HETATM 14099 O  O   . HOH L 3 .   ? -3.342  8.675   -31.019 1.00 30.00  ? 621 HOH D O   1 
HETATM 14100 O  O   . HOH L 3 .   ? -23.423 6.985   -61.921 1.00 33.42  ? 622 HOH D O   1 
HETATM 14101 O  O   . HOH L 3 .   ? -6.863  47.892  -17.035 1.00 29.36  ? 623 HOH D O   1 
HETATM 14102 O  O   . HOH L 3 .   ? -20.946 27.233  -19.540 1.00 25.43  ? 624 HOH D O   1 
HETATM 14103 O  O   . HOH L 3 .   ? -11.529 27.450  -4.338  1.00 31.06  ? 625 HOH D O   1 
HETATM 14104 O  O   . HOH L 3 .   ? -26.782 22.624  -37.234 1.00 25.62  ? 626 HOH D O   1 
HETATM 14105 O  O   . HOH L 3 .   ? -24.808 11.195  -39.011 1.00 34.87  ? 627 HOH D O   1 
HETATM 14106 O  O   . HOH L 3 .   ? -16.070 2.423   -56.562 1.00 25.39  ? 628 HOH D O   1 
HETATM 14107 O  O   . HOH L 3 .   ? -9.192  45.787  -21.980 1.00 34.77  ? 629 HOH D O   1 
HETATM 14108 O  O   . HOH L 3 .   ? -8.077  14.022  -35.578 1.00 30.77  ? 630 HOH D O   1 
HETATM 14109 O  O   . HOH L 3 .   ? -12.262 33.812  -23.359 1.00 24.86  ? 631 HOH D O   1 
HETATM 14110 O  O   . HOH L 3 .   ? -3.247  34.490  -24.389 1.00 28.44  ? 632 HOH D O   1 
HETATM 14111 O  O   . HOH L 3 .   ? 1.328   35.685  -16.445 1.00 33.91  ? 633 HOH D O   1 
HETATM 14112 O  O   . HOH L 3 .   ? 3.592   8.810   -33.462 1.00 46.88  ? 634 HOH D O   1 
HETATM 14113 O  O   . HOH L 3 .   ? -27.172 38.873  -8.823  1.00 39.92  ? 635 HOH D O   1 
HETATM 14114 O  O   . HOH L 3 .   ? -15.094 4.121   -62.864 1.00 37.57  ? 636 HOH D O   1 
HETATM 14115 O  O   . HOH L 3 .   ? -8.762  30.713  -0.032  1.00 24.81  ? 637 HOH D O   1 
HETATM 14116 O  O   . HOH L 3 .   ? -3.199  11.250  -46.151 1.00 29.99  ? 638 HOH D O   1 
HETATM 14117 O  O   . HOH L 3 .   ? -5.215  37.505  -9.557  1.00 29.04  ? 639 HOH D O   1 
HETATM 14118 O  O   . HOH L 3 .   ? -27.969 13.774  -64.194 1.00 30.00  ? 640 HOH D O   1 
HETATM 14119 O  O   . HOH L 3 .   ? -15.147 34.747  -4.948  1.00 36.15  ? 641 HOH D O   1 
HETATM 14120 O  O   . HOH L 3 .   ? -13.787 36.788  -26.724 1.00 29.27  ? 642 HOH D O   1 
HETATM 14121 O  O   . HOH L 3 .   ? -16.278 36.957  -8.329  1.00 30.00  ? 643 HOH D O   1 
HETATM 14122 O  O   . HOH L 3 .   ? -10.207 28.940  -16.880 1.00 25.03  ? 644 HOH D O   1 
HETATM 14123 O  O   . HOH L 3 .   ? -12.423 27.531  -22.758 1.00 24.83  ? 645 HOH D O   1 
HETATM 14124 O  O   . HOH L 3 .   ? -1.137  27.492  -14.076 1.00 22.90  ? 646 HOH D O   1 
HETATM 14125 O  O   . HOH L 3 .   ? -35.157 27.650  -15.558 1.00 42.96  ? 647 HOH D O   1 
HETATM 14126 O  O   . HOH L 3 .   ? -11.805 14.958  -49.385 1.00 30.82  ? 648 HOH D O   1 
HETATM 14127 O  O   . HOH L 3 .   ? -23.288 31.267  -29.351 1.00 31.72  ? 649 HOH D O   1 
HETATM 14128 O  O   . HOH L 3 .   ? -18.658 25.228  -27.361 1.00 24.46  ? 650 HOH D O   1 
HETATM 14129 O  O   . HOH L 3 .   ? -2.293  41.356  -11.055 1.00 29.94  ? 651 HOH D O   1 
HETATM 14130 O  O   . HOH L 3 .   ? -10.607 17.526  -37.966 1.00 26.27  ? 652 HOH D O   1 
HETATM 14131 O  O   . HOH L 3 .   ? -14.049 37.510  -2.524  1.00 31.30  ? 653 HOH D O   1 
HETATM 14132 O  O   . HOH L 3 .   ? -26.204 1.002   -30.831 1.00 34.55  ? 654 HOH D O   1 
HETATM 14133 O  O   . HOH L 3 .   ? -24.450 20.032  -27.565 1.00 28.13  ? 655 HOH D O   1 
HETATM 14134 O  O   . HOH L 3 .   ? -30.384 -5.528  -26.101 1.00 40.71  ? 656 HOH D O   1 
HETATM 14135 O  O   . HOH L 3 .   ? -42.139 14.753  -27.043 1.00 40.80  ? 657 HOH D O   1 
HETATM 14136 O  O   . HOH L 3 .   ? -46.686 19.142  -25.250 1.00 38.98  ? 658 HOH D O   1 
HETATM 14137 O  O   . HOH L 3 .   ? -24.932 37.557  -2.638  1.00 36.89  ? 659 HOH D O   1 
HETATM 14138 O  O   . HOH L 3 .   ? -17.658 22.746  -26.969 1.00 25.10  ? 660 HOH D O   1 
HETATM 14139 O  O   . HOH L 3 .   ? -12.090 20.116  -37.444 1.00 29.50  ? 661 HOH D O   1 
HETATM 14140 O  O   . HOH L 3 .   ? -21.622 12.667  -64.686 1.00 29.53  ? 662 HOH D O   1 
HETATM 14141 O  O   . HOH L 3 .   ? -24.230 8.806   -40.081 1.00 36.87  ? 663 HOH D O   1 
HETATM 14142 O  O   . HOH L 3 .   ? -18.003 26.921  -29.355 1.00 28.27  ? 664 HOH D O   1 
HETATM 14143 O  O   . HOH L 3 .   ? -26.823 15.718  -68.128 1.00 40.72  ? 665 HOH D O   1 
HETATM 14144 O  O   . HOH L 3 .   ? -7.622  56.071  -23.206 1.00 37.17  ? 666 HOH D O   1 
HETATM 14145 O  O   . HOH L 3 .   ? -29.564 32.752  -3.656  1.00 45.25  ? 667 HOH D O   1 
HETATM 14146 O  O   . HOH L 3 .   ? -5.205  27.635  -23.668 1.00 36.02  ? 668 HOH D O   1 
HETATM 14147 O  O   . HOH L 3 .   ? -20.135 6.201   -53.687 1.00 34.24  ? 669 HOH D O   1 
HETATM 14148 O  O   . HOH L 3 .   ? -36.743 10.985  -40.916 1.00 39.13  ? 670 HOH D O   1 
HETATM 14149 O  O   . HOH L 3 .   ? -28.940 10.535  -41.530 1.00 44.23  ? 671 HOH D O   1 
HETATM 14150 O  O   . HOH L 3 .   ? -6.882  13.357  -51.788 1.00 33.22  ? 672 HOH D O   1 
HETATM 14151 O  O   . HOH L 3 .   ? -14.996 22.594  -16.909 1.00 36.30  ? 673 HOH D O   1 
HETATM 14152 O  O   . HOH L 3 .   ? -7.157  49.654  -26.375 1.00 31.87  ? 674 HOH D O   1 
HETATM 14153 O  O   . HOH L 3 .   ? -12.521 26.637  -19.830 1.00 36.60  ? 675 HOH D O   1 
HETATM 14154 O  O   . HOH L 3 .   ? -18.083 17.538  -11.071 1.00 30.55  ? 676 HOH D O   1 
HETATM 14155 O  O   . HOH L 3 .   ? -21.551 38.692  -27.798 1.00 30.00  ? 677 HOH D O   1 
HETATM 14156 O  O   . HOH L 3 .   ? -23.760 14.161  -13.655 1.00 38.29  ? 678 HOH D O   1 
HETATM 14157 O  O   . HOH L 3 .   ? -23.641 10.392  -8.847  1.00 38.74  ? 679 HOH D O   1 
HETATM 14158 O  O   . HOH L 3 .   ? -27.018 12.296  -43.175 1.00 41.99  ? 680 HOH D O   1 
HETATM 14159 O  O   . HOH L 3 .   ? -5.135  35.322  -8.288  1.00 29.09  ? 681 HOH D O   1 
HETATM 14160 O  O   . HOH L 3 .   ? -30.396 19.758  -43.275 1.00 38.46  ? 682 HOH D O   1 
HETATM 14161 O  O   . HOH L 3 .   ? -14.591 23.027  -22.836 1.00 29.54  ? 683 HOH D O   1 
HETATM 14162 O  O   . HOH L 3 .   ? -6.010  16.687  -41.656 1.00 31.80  ? 684 HOH D O   1 
HETATM 14163 O  O   . HOH L 3 .   ? -15.528 19.704  -16.796 1.00 30.00  ? 685 HOH D O   1 
HETATM 14164 O  O   . HOH L 3 .   ? -14.514 16.205  -21.228 1.00 30.00  ? 686 HOH D O   1 
HETATM 14165 O  O   . HOH L 3 .   ? -4.355  3.949   -35.870 1.00 29.25  ? 687 HOH D O   1 
# 
