data_8QJU
# 
_entry.id   8QJU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8QJU         pdb_00008qju 10.2210/pdb8qju/pdb 
WWPDB D_1292132335 ?            ?                   
EMDB  EMD-18449    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-26 ? 
2 'EM metadata'     1 0 2025-03-26 ? 
3 FSC               1 0 2025-03-26 ? 
4 'Half map'        1 0 2025-03-26 1 
5 'Half map'        1 0 2025-03-26 2 
6 Image             1 0 2025-03-26 ? 
7 Mask              1 0 2025-03-26 1 
8 'Primary map'     1 0 2025-03-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8QJU 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Structure of the human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) protein' 
_pdbx_database_related.db_id          EMD-18449 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ajw1000@cam.ac.uk 
_pdbx_contact_author.name_first         Alan 
_pdbx_contact_author.name_last          Warren 
_pdbx_contact_author.name_mi            J 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9277-4553 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Faille, A.'   1 0000-0002-0714-4133 
'Warren, A.J.' 2 0000-0001-9277-4553 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of human PLCG2' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Faille, A.J.'         1 0000-0002-0714-4133 
primary 'Qamar, S.'            2 0009-0002-6011-5785 
primary 'Warren, A.J.'         3 0000-0001-9277-4553 
primary 'St George-Hyslop, P.' 4 0000-0003-0796-7209 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           '1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2' 
_entity.formula_weight             148074.578 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSK
DFERAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNS
ISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSH
YWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFP
VILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGT
FLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNP
HESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVS
KEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQ
QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQP
ESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKV
TFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLREKRVSNSKFYS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSK
DFERAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNS
ISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSH
YWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFP
VILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGT
FLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNP
HESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVS
KEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQ
QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQP
ESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKV
TFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLREKRVSNSKFYS
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    SER n 
1 3    THR n 
1 4    THR n 
1 5    VAL n 
1 6    ASN n 
1 7    VAL n 
1 8    ASP n 
1 9    SER n 
1 10   LEU n 
1 11   ALA n 
1 12   GLU n 
1 13   TYR n 
1 14   GLU n 
1 15   LYS n 
1 16   SER n 
1 17   GLN n 
1 18   ILE n 
1 19   LYS n 
1 20   ARG n 
1 21   ALA n 
1 22   LEU n 
1 23   GLU n 
1 24   LEU n 
1 25   GLY n 
1 26   THR n 
1 27   VAL n 
1 28   MET n 
1 29   THR n 
1 30   VAL n 
1 31   PHE n 
1 32   SER n 
1 33   PHE n 
1 34   ARG n 
1 35   LYS n 
1 36   SER n 
1 37   THR n 
1 38   PRO n 
1 39   GLU n 
1 40   ARG n 
1 41   ARG n 
1 42   THR n 
1 43   VAL n 
1 44   GLN n 
1 45   VAL n 
1 46   ILE n 
1 47   MET n 
1 48   GLU n 
1 49   THR n 
1 50   ARG n 
1 51   GLN n 
1 52   VAL n 
1 53   ALA n 
1 54   TRP n 
1 55   SER n 
1 56   LYS n 
1 57   THR n 
1 58   ALA n 
1 59   ASP n 
1 60   LYS n 
1 61   ILE n 
1 62   GLU n 
1 63   GLY n 
1 64   PHE n 
1 65   LEU n 
1 66   ASP n 
1 67   ILE n 
1 68   MET n 
1 69   GLU n 
1 70   ILE n 
1 71   LYS n 
1 72   GLU n 
1 73   ILE n 
1 74   ARG n 
1 75   PRO n 
1 76   GLY n 
1 77   LYS n 
1 78   ASN n 
1 79   SER n 
1 80   LYS n 
1 81   ASP n 
1 82   PHE n 
1 83   GLU n 
1 84   ARG n 
1 85   ALA n 
1 86   LYS n 
1 87   ALA n 
1 88   VAL n 
1 89   ARG n 
1 90   GLN n 
1 91   LYS n 
1 92   GLU n 
1 93   ASP n 
1 94   CYS n 
1 95   CYS n 
1 96   PHE n 
1 97   THR n 
1 98   ILE n 
1 99   LEU n 
1 100  TYR n 
1 101  GLY n 
1 102  THR n 
1 103  GLN n 
1 104  PHE n 
1 105  VAL n 
1 106  LEU n 
1 107  SER n 
1 108  THR n 
1 109  LEU n 
1 110  SER n 
1 111  LEU n 
1 112  ALA n 
1 113  ALA n 
1 114  ASP n 
1 115  SER n 
1 116  LYS n 
1 117  GLU n 
1 118  ASP n 
1 119  ALA n 
1 120  VAL n 
1 121  ASN n 
1 122  TRP n 
1 123  LEU n 
1 124  SER n 
1 125  GLY n 
1 126  LEU n 
1 127  LYS n 
1 128  ILE n 
1 129  LEU n 
1 130  HIS n 
1 131  GLN n 
1 132  GLU n 
1 133  ALA n 
1 134  MET n 
1 135  ASN n 
1 136  ALA n 
1 137  SER n 
1 138  THR n 
1 139  PRO n 
1 140  THR n 
1 141  ILE n 
1 142  ILE n 
1 143  GLU n 
1 144  SER n 
1 145  TRP n 
1 146  LEU n 
1 147  ARG n 
1 148  LYS n 
1 149  GLN n 
1 150  ILE n 
1 151  TYR n 
1 152  SER n 
1 153  VAL n 
1 154  ASP n 
1 155  GLN n 
1 156  THR n 
1 157  ARG n 
1 158  ARG n 
1 159  ASN n 
1 160  SER n 
1 161  ILE n 
1 162  SER n 
1 163  LEU n 
1 164  ARG n 
1 165  GLU n 
1 166  LEU n 
1 167  LYS n 
1 168  THR n 
1 169  ILE n 
1 170  LEU n 
1 171  PRO n 
1 172  LEU n 
1 173  ILE n 
1 174  ASN n 
1 175  PHE n 
1 176  LYS n 
1 177  VAL n 
1 178  SER n 
1 179  SER n 
1 180  ALA n 
1 181  LYS n 
1 182  PHE n 
1 183  LEU n 
1 184  LYS n 
1 185  ASP n 
1 186  LYS n 
1 187  PHE n 
1 188  VAL n 
1 189  GLU n 
1 190  ILE n 
1 191  GLY n 
1 192  ALA n 
1 193  HIS n 
1 194  LYS n 
1 195  ASP n 
1 196  GLU n 
1 197  LEU n 
1 198  SER n 
1 199  PHE n 
1 200  GLU n 
1 201  GLN n 
1 202  PHE n 
1 203  HIS n 
1 204  LEU n 
1 205  PHE n 
1 206  TYR n 
1 207  LYS n 
1 208  LYS n 
1 209  LEU n 
1 210  MET n 
1 211  PHE n 
1 212  GLU n 
1 213  GLN n 
1 214  GLN n 
1 215  LYS n 
1 216  SER n 
1 217  ILE n 
1 218  LEU n 
1 219  ASP n 
1 220  GLU n 
1 221  PHE n 
1 222  LYS n 
1 223  LYS n 
1 224  ASP n 
1 225  SER n 
1 226  SER n 
1 227  VAL n 
1 228  PHE n 
1 229  ILE n 
1 230  LEU n 
1 231  GLY n 
1 232  ASN n 
1 233  THR n 
1 234  ASP n 
1 235  ARG n 
1 236  PRO n 
1 237  ASP n 
1 238  ALA n 
1 239  SER n 
1 240  ALA n 
1 241  VAL n 
1 242  TYR n 
1 243  LEU n 
1 244  HIS n 
1 245  ASP n 
1 246  PHE n 
1 247  GLN n 
1 248  ARG n 
1 249  PHE n 
1 250  LEU n 
1 251  ILE n 
1 252  HIS n 
1 253  GLU n 
1 254  GLN n 
1 255  GLN n 
1 256  GLU n 
1 257  HIS n 
1 258  TRP n 
1 259  ALA n 
1 260  GLN n 
1 261  ASP n 
1 262  LEU n 
1 263  ASN n 
1 264  LYS n 
1 265  VAL n 
1 266  ARG n 
1 267  GLU n 
1 268  ARG n 
1 269  MET n 
1 270  THR n 
1 271  LYS n 
1 272  PHE n 
1 273  ILE n 
1 274  ASP n 
1 275  ASP n 
1 276  THR n 
1 277  MET n 
1 278  ARG n 
1 279  GLU n 
1 280  THR n 
1 281  ALA n 
1 282  GLU n 
1 283  PRO n 
1 284  PHE n 
1 285  LEU n 
1 286  PHE n 
1 287  VAL n 
1 288  ASP n 
1 289  GLU n 
1 290  PHE n 
1 291  LEU n 
1 292  THR n 
1 293  TYR n 
1 294  LEU n 
1 295  PHE n 
1 296  SER n 
1 297  ARG n 
1 298  GLU n 
1 299  ASN n 
1 300  SER n 
1 301  ILE n 
1 302  TRP n 
1 303  ASP n 
1 304  GLU n 
1 305  LYS n 
1 306  TYR n 
1 307  ASP n 
1 308  ALA n 
1 309  VAL n 
1 310  ASP n 
1 311  MET n 
1 312  GLN n 
1 313  ASP n 
1 314  MET n 
1 315  ASN n 
1 316  ASN n 
1 317  PRO n 
1 318  LEU n 
1 319  SER n 
1 320  HIS n 
1 321  TYR n 
1 322  TRP n 
1 323  ILE n 
1 324  SER n 
1 325  SER n 
1 326  SER n 
1 327  HIS n 
1 328  ASN n 
1 329  THR n 
1 330  TYR n 
1 331  LEU n 
1 332  THR n 
1 333  GLY n 
1 334  ASP n 
1 335  GLN n 
1 336  LEU n 
1 337  ARG n 
1 338  SER n 
1 339  GLU n 
1 340  SER n 
1 341  SER n 
1 342  PRO n 
1 343  GLU n 
1 344  ALA n 
1 345  TYR n 
1 346  ILE n 
1 347  ARG n 
1 348  CYS n 
1 349  LEU n 
1 350  ARG n 
1 351  MET n 
1 352  GLY n 
1 353  CYS n 
1 354  ARG n 
1 355  CYS n 
1 356  ILE n 
1 357  GLU n 
1 358  LEU n 
1 359  ASP n 
1 360  CYS n 
1 361  TRP n 
1 362  ASP n 
1 363  GLY n 
1 364  PRO n 
1 365  ASP n 
1 366  GLY n 
1 367  LYS n 
1 368  PRO n 
1 369  VAL n 
1 370  ILE n 
1 371  TYR n 
1 372  HIS n 
1 373  GLY n 
1 374  TRP n 
1 375  THR n 
1 376  ARG n 
1 377  THR n 
1 378  THR n 
1 379  LYS n 
1 380  ILE n 
1 381  LYS n 
1 382  PHE n 
1 383  ASP n 
1 384  ASP n 
1 385  VAL n 
1 386  VAL n 
1 387  GLN n 
1 388  ALA n 
1 389  ILE n 
1 390  LYS n 
1 391  ASP n 
1 392  HIS n 
1 393  ALA n 
1 394  PHE n 
1 395  VAL n 
1 396  THR n 
1 397  SER n 
1 398  SER n 
1 399  PHE n 
1 400  PRO n 
1 401  VAL n 
1 402  ILE n 
1 403  LEU n 
1 404  SER n 
1 405  ILE n 
1 406  GLU n 
1 407  GLU n 
1 408  HIS n 
1 409  CYS n 
1 410  SER n 
1 411  VAL n 
1 412  GLU n 
1 413  GLN n 
1 414  GLN n 
1 415  ARG n 
1 416  HIS n 
1 417  MET n 
1 418  ALA n 
1 419  LYS n 
1 420  ALA n 
1 421  PHE n 
1 422  LYS n 
1 423  GLU n 
1 424  VAL n 
1 425  PHE n 
1 426  GLY n 
1 427  ASP n 
1 428  LEU n 
1 429  LEU n 
1 430  LEU n 
1 431  THR n 
1 432  LYS n 
1 433  PRO n 
1 434  THR n 
1 435  GLU n 
1 436  ALA n 
1 437  SER n 
1 438  ALA n 
1 439  ASP n 
1 440  GLN n 
1 441  LEU n 
1 442  PRO n 
1 443  SER n 
1 444  PRO n 
1 445  SER n 
1 446  GLN n 
1 447  LEU n 
1 448  ARG n 
1 449  GLU n 
1 450  LYS n 
1 451  ILE n 
1 452  ILE n 
1 453  ILE n 
1 454  LYS n 
1 455  HIS n 
1 456  LYS n 
1 457  LYS n 
1 458  LEU n 
1 459  GLY n 
1 460  PRO n 
1 461  ARG n 
1 462  GLY n 
1 463  ASP n 
1 464  VAL n 
1 465  ASP n 
1 466  VAL n 
1 467  ASN n 
1 468  MET n 
1 469  GLU n 
1 470  ASP n 
1 471  LYS n 
1 472  LYS n 
1 473  ASP n 
1 474  GLU n 
1 475  HIS n 
1 476  LYS n 
1 477  GLN n 
1 478  GLN n 
1 479  GLY n 
1 480  GLU n 
1 481  LEU n 
1 482  TYR n 
1 483  MET n 
1 484  TRP n 
1 485  ASP n 
1 486  SER n 
1 487  ILE n 
1 488  ASP n 
1 489  GLN n 
1 490  LYS n 
1 491  TRP n 
1 492  THR n 
1 493  ARG n 
1 494  HIS n 
1 495  TYR n 
1 496  CYS n 
1 497  ALA n 
1 498  ILE n 
1 499  ALA n 
1 500  ASP n 
1 501  ALA n 
1 502  LYS n 
1 503  LEU n 
1 504  SER n 
1 505  PHE n 
1 506  SER n 
1 507  ASP n 
1 508  ASP n 
1 509  ILE n 
1 510  GLU n 
1 511  GLN n 
1 512  THR n 
1 513  MET n 
1 514  GLU n 
1 515  GLU n 
1 516  GLU n 
1 517  VAL n 
1 518  PRO n 
1 519  GLN n 
1 520  ASP n 
1 521  ILE n 
1 522  PRO n 
1 523  PRO n 
1 524  THR n 
1 525  GLU n 
1 526  LEU n 
1 527  HIS n 
1 528  PHE n 
1 529  GLY n 
1 530  GLU n 
1 531  LYS n 
1 532  TRP n 
1 533  PHE n 
1 534  HIS n 
1 535  LYS n 
1 536  LYS n 
1 537  VAL n 
1 538  GLU n 
1 539  LYS n 
1 540  ARG n 
1 541  THR n 
1 542  SER n 
1 543  ALA n 
1 544  GLU n 
1 545  LYS n 
1 546  LEU n 
1 547  LEU n 
1 548  GLN n 
1 549  GLU n 
1 550  TYR n 
1 551  CYS n 
1 552  MET n 
1 553  GLU n 
1 554  THR n 
1 555  GLY n 
1 556  GLY n 
1 557  LYS n 
1 558  ASP n 
1 559  GLY n 
1 560  THR n 
1 561  PHE n 
1 562  LEU n 
1 563  VAL n 
1 564  ARG n 
1 565  GLU n 
1 566  SER n 
1 567  GLU n 
1 568  THR n 
1 569  PHE n 
1 570  PRO n 
1 571  ASN n 
1 572  ASP n 
1 573  TYR n 
1 574  THR n 
1 575  LEU n 
1 576  SER n 
1 577  PHE n 
1 578  TRP n 
1 579  ARG n 
1 580  SER n 
1 581  GLY n 
1 582  ARG n 
1 583  VAL n 
1 584  GLN n 
1 585  HIS n 
1 586  CYS n 
1 587  ARG n 
1 588  ILE n 
1 589  ARG n 
1 590  SER n 
1 591  THR n 
1 592  MET n 
1 593  GLU n 
1 594  GLY n 
1 595  GLY n 
1 596  THR n 
1 597  LEU n 
1 598  LYS n 
1 599  TYR n 
1 600  TYR n 
1 601  LEU n 
1 602  THR n 
1 603  ASP n 
1 604  ASN n 
1 605  LEU n 
1 606  THR n 
1 607  PHE n 
1 608  SER n 
1 609  SER n 
1 610  ILE n 
1 611  TYR n 
1 612  ALA n 
1 613  LEU n 
1 614  ILE n 
1 615  GLN n 
1 616  HIS n 
1 617  TYR n 
1 618  ARG n 
1 619  GLU n 
1 620  THR n 
1 621  HIS n 
1 622  LEU n 
1 623  ARG n 
1 624  CYS n 
1 625  ALA n 
1 626  GLU n 
1 627  PHE n 
1 628  GLU n 
1 629  LEU n 
1 630  ARG n 
1 631  LEU n 
1 632  THR n 
1 633  ASP n 
1 634  PRO n 
1 635  VAL n 
1 636  PRO n 
1 637  ASN n 
1 638  PRO n 
1 639  ASN n 
1 640  PRO n 
1 641  HIS n 
1 642  GLU n 
1 643  SER n 
1 644  LYS n 
1 645  PRO n 
1 646  TRP n 
1 647  TYR n 
1 648  TYR n 
1 649  ASP n 
1 650  SER n 
1 651  LEU n 
1 652  SER n 
1 653  ARG n 
1 654  GLY n 
1 655  GLU n 
1 656  ALA n 
1 657  GLU n 
1 658  ASP n 
1 659  MET n 
1 660  LEU n 
1 661  MET n 
1 662  ARG n 
1 663  ILE n 
1 664  PRO n 
1 665  ARG n 
1 666  ASP n 
1 667  GLY n 
1 668  ALA n 
1 669  PHE n 
1 670  LEU n 
1 671  ILE n 
1 672  ARG n 
1 673  LYS n 
1 674  ARG n 
1 675  GLU n 
1 676  GLY n 
1 677  SER n 
1 678  ASP n 
1 679  SER n 
1 680  TYR n 
1 681  ALA n 
1 682  ILE n 
1 683  THR n 
1 684  PHE n 
1 685  ARG n 
1 686  ALA n 
1 687  ARG n 
1 688  GLY n 
1 689  LYS n 
1 690  VAL n 
1 691  LYS n 
1 692  HIS n 
1 693  CYS n 
1 694  ARG n 
1 695  ILE n 
1 696  ASN n 
1 697  ARG n 
1 698  ASP n 
1 699  GLY n 
1 700  ARG n 
1 701  HIS n 
1 702  PHE n 
1 703  VAL n 
1 704  LEU n 
1 705  GLY n 
1 706  THR n 
1 707  SER n 
1 708  ALA n 
1 709  TYR n 
1 710  PHE n 
1 711  GLU n 
1 712  SER n 
1 713  LEU n 
1 714  VAL n 
1 715  GLU n 
1 716  LEU n 
1 717  VAL n 
1 718  SER n 
1 719  TYR n 
1 720  TYR n 
1 721  GLU n 
1 722  LYS n 
1 723  HIS n 
1 724  SER n 
1 725  LEU n 
1 726  TYR n 
1 727  ARG n 
1 728  LYS n 
1 729  MET n 
1 730  ARG n 
1 731  LEU n 
1 732  ARG n 
1 733  TYR n 
1 734  PRO n 
1 735  VAL n 
1 736  THR n 
1 737  PRO n 
1 738  GLU n 
1 739  LEU n 
1 740  LEU n 
1 741  GLU n 
1 742  ARG n 
1 743  TYR n 
1 744  ASN n 
1 745  MET n 
1 746  GLU n 
1 747  ARG n 
1 748  ASP n 
1 749  ILE n 
1 750  ASN n 
1 751  SER n 
1 752  LEU n 
1 753  TYR n 
1 754  ASP n 
1 755  VAL n 
1 756  SER n 
1 757  ARG n 
1 758  MET n 
1 759  TYR n 
1 760  VAL n 
1 761  ASP n 
1 762  PRO n 
1 763  SER n 
1 764  GLU n 
1 765  ILE n 
1 766  ASN n 
1 767  PRO n 
1 768  SER n 
1 769  MET n 
1 770  PRO n 
1 771  GLN n 
1 772  ARG n 
1 773  THR n 
1 774  VAL n 
1 775  LYS n 
1 776  ALA n 
1 777  LEU n 
1 778  TYR n 
1 779  ASP n 
1 780  TYR n 
1 781  LYS n 
1 782  ALA n 
1 783  LYS n 
1 784  ARG n 
1 785  SER n 
1 786  ASP n 
1 787  GLU n 
1 788  LEU n 
1 789  SER n 
1 790  PHE n 
1 791  CYS n 
1 792  ARG n 
1 793  GLY n 
1 794  ALA n 
1 795  LEU n 
1 796  ILE n 
1 797  HIS n 
1 798  ASN n 
1 799  VAL n 
1 800  SER n 
1 801  LYS n 
1 802  GLU n 
1 803  PRO n 
1 804  GLY n 
1 805  GLY n 
1 806  TRP n 
1 807  TRP n 
1 808  LYS n 
1 809  GLY n 
1 810  ASP n 
1 811  TYR n 
1 812  GLY n 
1 813  THR n 
1 814  ARG n 
1 815  ILE n 
1 816  GLN n 
1 817  GLN n 
1 818  TYR n 
1 819  PHE n 
1 820  PRO n 
1 821  SER n 
1 822  ASN n 
1 823  TYR n 
1 824  VAL n 
1 825  GLU n 
1 826  ASP n 
1 827  ILE n 
1 828  SER n 
1 829  THR n 
1 830  ALA n 
1 831  ASP n 
1 832  PHE n 
1 833  GLU n 
1 834  GLU n 
1 835  LEU n 
1 836  GLU n 
1 837  LYS n 
1 838  GLN n 
1 839  ILE n 
1 840  ILE n 
1 841  GLU n 
1 842  ASP n 
1 843  ASN n 
1 844  PRO n 
1 845  LEU n 
1 846  GLY n 
1 847  SER n 
1 848  LEU n 
1 849  CYS n 
1 850  ARG n 
1 851  GLY n 
1 852  ILE n 
1 853  LEU n 
1 854  ASP n 
1 855  LEU n 
1 856  ASN n 
1 857  THR n 
1 858  TYR n 
1 859  ASN n 
1 860  VAL n 
1 861  VAL n 
1 862  LYS n 
1 863  ALA n 
1 864  PRO n 
1 865  GLN n 
1 866  GLY n 
1 867  LYS n 
1 868  ASN n 
1 869  GLN n 
1 870  LYS n 
1 871  SER n 
1 872  PHE n 
1 873  VAL n 
1 874  PHE n 
1 875  ILE n 
1 876  LEU n 
1 877  GLU n 
1 878  PRO n 
1 879  LYS n 
1 880  GLN n 
1 881  GLN n 
1 882  GLY n 
1 883  ASP n 
1 884  PRO n 
1 885  PRO n 
1 886  VAL n 
1 887  GLU n 
1 888  PHE n 
1 889  ALA n 
1 890  THR n 
1 891  ASP n 
1 892  ARG n 
1 893  VAL n 
1 894  GLU n 
1 895  GLU n 
1 896  LEU n 
1 897  PHE n 
1 898  GLU n 
1 899  TRP n 
1 900  PHE n 
1 901  GLN n 
1 902  SER n 
1 903  ILE n 
1 904  ARG n 
1 905  GLU n 
1 906  ILE n 
1 907  THR n 
1 908  TRP n 
1 909  LYS n 
1 910  ILE n 
1 911  ASP n 
1 912  THR n 
1 913  LYS n 
1 914  GLU n 
1 915  ASN n 
1 916  ASN n 
1 917  MET n 
1 918  LYS n 
1 919  TYR n 
1 920  TRP n 
1 921  GLU n 
1 922  LYS n 
1 923  ASN n 
1 924  GLN n 
1 925  SER n 
1 926  ILE n 
1 927  ALA n 
1 928  ILE n 
1 929  GLU n 
1 930  LEU n 
1 931  SER n 
1 932  ASP n 
1 933  LEU n 
1 934  VAL n 
1 935  VAL n 
1 936  TYR n 
1 937  CYS n 
1 938  LYS n 
1 939  PRO n 
1 940  THR n 
1 941  SER n 
1 942  LYS n 
1 943  THR n 
1 944  LYS n 
1 945  ASP n 
1 946  ASN n 
1 947  LEU n 
1 948  GLU n 
1 949  ASN n 
1 950  PRO n 
1 951  ASP n 
1 952  PHE n 
1 953  ARG n 
1 954  GLU n 
1 955  ILE n 
1 956  ARG n 
1 957  SER n 
1 958  PHE n 
1 959  VAL n 
1 960  GLU n 
1 961  THR n 
1 962  LYS n 
1 963  ALA n 
1 964  ASP n 
1 965  SER n 
1 966  ILE n 
1 967  ILE n 
1 968  ARG n 
1 969  GLN n 
1 970  LYS n 
1 971  PRO n 
1 972  VAL n 
1 973  ASP n 
1 974  LEU n 
1 975  LEU n 
1 976  LYS n 
1 977  TYR n 
1 978  ASN n 
1 979  GLN n 
1 980  LYS n 
1 981  GLY n 
1 982  LEU n 
1 983  THR n 
1 984  ARG n 
1 985  VAL n 
1 986  TYR n 
1 987  PRO n 
1 988  LYS n 
1 989  GLY n 
1 990  GLN n 
1 991  ARG n 
1 992  VAL n 
1 993  ASP n 
1 994  SER n 
1 995  SER n 
1 996  ASN n 
1 997  TYR n 
1 998  ASP n 
1 999  PRO n 
1 1000 PHE n 
1 1001 ARG n 
1 1002 LEU n 
1 1003 TRP n 
1 1004 LEU n 
1 1005 CYS n 
1 1006 GLY n 
1 1007 SER n 
1 1008 GLN n 
1 1009 MET n 
1 1010 VAL n 
1 1011 ALA n 
1 1012 LEU n 
1 1013 ASN n 
1 1014 PHE n 
1 1015 GLN n 
1 1016 THR n 
1 1017 ALA n 
1 1018 ASP n 
1 1019 LYS n 
1 1020 TYR n 
1 1021 MET n 
1 1022 GLN n 
1 1023 MET n 
1 1024 ASN n 
1 1025 HIS n 
1 1026 ALA n 
1 1027 LEU n 
1 1028 PHE n 
1 1029 SER n 
1 1030 LEU n 
1 1031 ASN n 
1 1032 GLY n 
1 1033 ARG n 
1 1034 THR n 
1 1035 GLY n 
1 1036 TYR n 
1 1037 VAL n 
1 1038 LEU n 
1 1039 GLN n 
1 1040 PRO n 
1 1041 GLU n 
1 1042 SER n 
1 1043 MET n 
1 1044 ARG n 
1 1045 THR n 
1 1046 GLU n 
1 1047 LYS n 
1 1048 TYR n 
1 1049 ASP n 
1 1050 PRO n 
1 1051 MET n 
1 1052 PRO n 
1 1053 PRO n 
1 1054 GLU n 
1 1055 SER n 
1 1056 GLN n 
1 1057 ARG n 
1 1058 LYS n 
1 1059 ILE n 
1 1060 LEU n 
1 1061 MET n 
1 1062 THR n 
1 1063 LEU n 
1 1064 THR n 
1 1065 VAL n 
1 1066 LYS n 
1 1067 VAL n 
1 1068 LEU n 
1 1069 GLY n 
1 1070 ALA n 
1 1071 ARG n 
1 1072 HIS n 
1 1073 LEU n 
1 1074 PRO n 
1 1075 LYS n 
1 1076 LEU n 
1 1077 GLY n 
1 1078 ARG n 
1 1079 SER n 
1 1080 ILE n 
1 1081 ALA n 
1 1082 CYS n 
1 1083 PRO n 
1 1084 PHE n 
1 1085 VAL n 
1 1086 GLU n 
1 1087 VAL n 
1 1088 GLU n 
1 1089 ILE n 
1 1090 CYS n 
1 1091 GLY n 
1 1092 ALA n 
1 1093 GLU n 
1 1094 TYR n 
1 1095 ASP n 
1 1096 ASN n 
1 1097 ASN n 
1 1098 LYS n 
1 1099 PHE n 
1 1100 LYS n 
1 1101 THR n 
1 1102 THR n 
1 1103 VAL n 
1 1104 VAL n 
1 1105 ASN n 
1 1106 ASP n 
1 1107 ASN n 
1 1108 GLY n 
1 1109 LEU n 
1 1110 SER n 
1 1111 PRO n 
1 1112 ILE n 
1 1113 TRP n 
1 1114 ALA n 
1 1115 PRO n 
1 1116 THR n 
1 1117 GLN n 
1 1118 GLU n 
1 1119 LYS n 
1 1120 VAL n 
1 1121 THR n 
1 1122 PHE n 
1 1123 GLU n 
1 1124 ILE n 
1 1125 TYR n 
1 1126 ASP n 
1 1127 PRO n 
1 1128 ASN n 
1 1129 LEU n 
1 1130 ALA n 
1 1131 PHE n 
1 1132 LEU n 
1 1133 ARG n 
1 1134 PHE n 
1 1135 VAL n 
1 1136 VAL n 
1 1137 TYR n 
1 1138 GLU n 
1 1139 GLU n 
1 1140 ASP n 
1 1141 MET n 
1 1142 PHE n 
1 1143 SER n 
1 1144 ASP n 
1 1145 PRO n 
1 1146 ASN n 
1 1147 PHE n 
1 1148 LEU n 
1 1149 ALA n 
1 1150 HIS n 
1 1151 ALA n 
1 1152 THR n 
1 1153 TYR n 
1 1154 PRO n 
1 1155 ILE n 
1 1156 LYS n 
1 1157 ALA n 
1 1158 VAL n 
1 1159 LYS n 
1 1160 SER n 
1 1161 GLY n 
1 1162 PHE n 
1 1163 ARG n 
1 1164 SER n 
1 1165 VAL n 
1 1166 PRO n 
1 1167 LEU n 
1 1168 LYS n 
1 1169 ASN n 
1 1170 GLY n 
1 1171 TYR n 
1 1172 SER n 
1 1173 GLU n 
1 1174 ASP n 
1 1175 ILE n 
1 1176 GLU n 
1 1177 LEU n 
1 1178 ALA n 
1 1179 SER n 
1 1180 LEU n 
1 1181 LEU n 
1 1182 VAL n 
1 1183 PHE n 
1 1184 CYS n 
1 1185 GLU n 
1 1186 MET n 
1 1187 ARG n 
1 1188 PRO n 
1 1189 VAL n 
1 1190 LEU n 
1 1191 GLU n 
1 1192 SER n 
1 1193 GLU n 
1 1194 GLU n 
1 1195 GLU n 
1 1196 LEU n 
1 1197 TYR n 
1 1198 SER n 
1 1199 SER n 
1 1200 CYS n 
1 1201 ARG n 
1 1202 GLN n 
1 1203 LEU n 
1 1204 ARG n 
1 1205 ARG n 
1 1206 ARG n 
1 1207 GLN n 
1 1208 GLU n 
1 1209 GLU n 
1 1210 LEU n 
1 1211 ASN n 
1 1212 ASN n 
1 1213 GLN n 
1 1214 LEU n 
1 1215 PHE n 
1 1216 LEU n 
1 1217 TYR n 
1 1218 ASP n 
1 1219 THR n 
1 1220 HIS n 
1 1221 GLN n 
1 1222 ASN n 
1 1223 LEU n 
1 1224 ARG n 
1 1225 ASN n 
1 1226 ALA n 
1 1227 ASN n 
1 1228 ARG n 
1 1229 ASP n 
1 1230 ALA n 
1 1231 LEU n 
1 1232 VAL n 
1 1233 LYS n 
1 1234 GLU n 
1 1235 PHE n 
1 1236 SER n 
1 1237 VAL n 
1 1238 ASN n 
1 1239 GLU n 
1 1240 ASN n 
1 1241 GLN n 
1 1242 LEU n 
1 1243 GLN n 
1 1244 LEU n 
1 1245 TYR n 
1 1246 GLN n 
1 1247 GLU n 
1 1248 LYS n 
1 1249 CYS n 
1 1250 ASN n 
1 1251 LYS n 
1 1252 ARG n 
1 1253 LEU n 
1 1254 ARG n 
1 1255 GLU n 
1 1256 LYS n 
1 1257 ARG n 
1 1258 VAL n 
1 1259 SER n 
1 1260 ASN n 
1 1261 SER n 
1 1262 LYS n 
1 1263 PHE n 
1 1264 TYR n 
1 1265 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1265 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PLCG2 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?    ?   ?   A . n 
A 1 2    SER 2    2    ?    ?   ?   A . n 
A 1 3    THR 3    3    ?    ?   ?   A . n 
A 1 4    THR 4    4    ?    ?   ?   A . n 
A 1 5    VAL 5    5    ?    ?   ?   A . n 
A 1 6    ASN 6    6    ?    ?   ?   A . n 
A 1 7    VAL 7    7    ?    ?   ?   A . n 
A 1 8    ASP 8    8    ?    ?   ?   A . n 
A 1 9    SER 9    9    ?    ?   ?   A . n 
A 1 10   LEU 10   10   ?    ?   ?   A . n 
A 1 11   ALA 11   11   11   ALA ALA A . n 
A 1 12   GLU 12   12   12   GLU GLU A . n 
A 1 13   TYR 13   13   13   TYR TYR A . n 
A 1 14   GLU 14   14   14   GLU GLU A . n 
A 1 15   LYS 15   15   15   LYS LYS A . n 
A 1 16   SER 16   16   16   SER SER A . n 
A 1 17   GLN 17   17   17   GLN GLN A . n 
A 1 18   ILE 18   18   18   ILE ILE A . n 
A 1 19   LYS 19   19   19   LYS LYS A . n 
A 1 20   ARG 20   20   20   ARG ARG A . n 
A 1 21   ALA 21   21   21   ALA ALA A . n 
A 1 22   LEU 22   22   22   LEU LEU A . n 
A 1 23   GLU 23   23   23   GLU GLU A . n 
A 1 24   LEU 24   24   24   LEU LEU A . n 
A 1 25   GLY 25   25   25   GLY GLY A . n 
A 1 26   THR 26   26   26   THR THR A . n 
A 1 27   VAL 27   27   27   VAL VAL A . n 
A 1 28   MET 28   28   28   MET MET A . n 
A 1 29   THR 29   29   29   THR THR A . n 
A 1 30   VAL 30   30   30   VAL VAL A . n 
A 1 31   PHE 31   31   31   PHE PHE A . n 
A 1 32   SER 32   32   32   SER SER A . n 
A 1 33   PHE 33   33   33   PHE PHE A . n 
A 1 34   ARG 34   34   34   ARG ARG A . n 
A 1 35   LYS 35   35   35   LYS LYS A . n 
A 1 36   SER 36   36   36   SER SER A . n 
A 1 37   THR 37   37   37   THR THR A . n 
A 1 38   PRO 38   38   38   PRO PRO A . n 
A 1 39   GLU 39   39   39   GLU GLU A . n 
A 1 40   ARG 40   40   40   ARG ARG A . n 
A 1 41   ARG 41   41   41   ARG ARG A . n 
A 1 42   THR 42   42   42   THR THR A . n 
A 1 43   VAL 43   43   43   VAL VAL A . n 
A 1 44   GLN 44   44   44   GLN GLN A . n 
A 1 45   VAL 45   45   45   VAL VAL A . n 
A 1 46   ILE 46   46   46   ILE ILE A . n 
A 1 47   MET 47   47   47   MET MET A . n 
A 1 48   GLU 48   48   48   GLU GLU A . n 
A 1 49   THR 49   49   49   THR THR A . n 
A 1 50   ARG 50   50   50   ARG ARG A . n 
A 1 51   GLN 51   51   51   GLN GLN A . n 
A 1 52   VAL 52   52   52   VAL VAL A . n 
A 1 53   ALA 53   53   53   ALA ALA A . n 
A 1 54   TRP 54   54   54   TRP TRP A . n 
A 1 55   SER 55   55   55   SER SER A . n 
A 1 56   LYS 56   56   56   LYS LYS A . n 
A 1 57   THR 57   57   57   THR THR A . n 
A 1 58   ALA 58   58   58   ALA ALA A . n 
A 1 59   ASP 59   59   59   ASP ASP A . n 
A 1 60   LYS 60   60   60   LYS LYS A . n 
A 1 61   ILE 61   61   61   ILE ILE A . n 
A 1 62   GLU 62   62   62   GLU GLU A . n 
A 1 63   GLY 63   63   63   GLY GLY A . n 
A 1 64   PHE 64   64   64   PHE PHE A . n 
A 1 65   LEU 65   65   65   LEU LEU A . n 
A 1 66   ASP 66   66   66   ASP ASP A . n 
A 1 67   ILE 67   67   67   ILE ILE A . n 
A 1 68   MET 68   68   68   MET MET A . n 
A 1 69   GLU 69   69   69   GLU GLU A . n 
A 1 70   ILE 70   70   70   ILE ILE A . n 
A 1 71   LYS 71   71   71   LYS LYS A . n 
A 1 72   GLU 72   72   72   GLU GLU A . n 
A 1 73   ILE 73   73   73   ILE ILE A . n 
A 1 74   ARG 74   74   74   ARG ARG A . n 
A 1 75   PRO 75   75   75   PRO PRO A . n 
A 1 76   GLY 76   76   76   GLY GLY A . n 
A 1 77   LYS 77   77   77   LYS LYS A . n 
A 1 78   ASN 78   78   78   ASN ASN A . n 
A 1 79   SER 79   79   79   SER SER A . n 
A 1 80   LYS 80   80   80   LYS LYS A . n 
A 1 81   ASP 81   81   81   ASP ASP A . n 
A 1 82   PHE 82   82   82   PHE PHE A . n 
A 1 83   GLU 83   83   83   GLU GLU A . n 
A 1 84   ARG 84   84   84   ARG ARG A . n 
A 1 85   ALA 85   85   85   ALA ALA A . n 
A 1 86   LYS 86   86   86   LYS LYS A . n 
A 1 87   ALA 87   87   87   ALA ALA A . n 
A 1 88   VAL 88   88   88   VAL VAL A . n 
A 1 89   ARG 89   89   89   ARG ARG A . n 
A 1 90   GLN 90   90   90   GLN GLN A . n 
A 1 91   LYS 91   91   91   LYS LYS A . n 
A 1 92   GLU 92   92   92   GLU GLU A . n 
A 1 93   ASP 93   93   93   ASP ASP A . n 
A 1 94   CYS 94   94   94   CYS CYS A . n 
A 1 95   CYS 95   95   95   CYS CYS A . n 
A 1 96   PHE 96   96   96   PHE PHE A . n 
A 1 97   THR 97   97   97   THR THR A . n 
A 1 98   ILE 98   98   98   ILE ILE A . n 
A 1 99   LEU 99   99   99   LEU LEU A . n 
A 1 100  TYR 100  100  100  TYR TYR A . n 
A 1 101  GLY 101  101  101  GLY GLY A . n 
A 1 102  THR 102  102  102  THR THR A . n 
A 1 103  GLN 103  103  103  GLN GLN A . n 
A 1 104  PHE 104  104  104  PHE PHE A . n 
A 1 105  VAL 105  105  105  VAL VAL A . n 
A 1 106  LEU 106  106  106  LEU LEU A . n 
A 1 107  SER 107  107  107  SER SER A . n 
A 1 108  THR 108  108  108  THR THR A . n 
A 1 109  LEU 109  109  109  LEU LEU A . n 
A 1 110  SER 110  110  110  SER SER A . n 
A 1 111  LEU 111  111  111  LEU LEU A . n 
A 1 112  ALA 112  112  112  ALA ALA A . n 
A 1 113  ALA 113  113  113  ALA ALA A . n 
A 1 114  ASP 114  114  114  ASP ASP A . n 
A 1 115  SER 115  115  115  SER SER A . n 
A 1 116  LYS 116  116  116  LYS LYS A . n 
A 1 117  GLU 117  117  117  GLU GLU A . n 
A 1 118  ASP 118  118  118  ASP ASP A . n 
A 1 119  ALA 119  119  119  ALA ALA A . n 
A 1 120  VAL 120  120  120  VAL VAL A . n 
A 1 121  ASN 121  121  121  ASN ASN A . n 
A 1 122  TRP 122  122  122  TRP TRP A . n 
A 1 123  LEU 123  123  123  LEU LEU A . n 
A 1 124  SER 124  124  124  SER SER A . n 
A 1 125  GLY 125  125  125  GLY GLY A . n 
A 1 126  LEU 126  126  126  LEU LEU A . n 
A 1 127  LYS 127  127  127  LYS LYS A . n 
A 1 128  ILE 128  128  128  ILE ILE A . n 
A 1 129  LEU 129  129  129  LEU LEU A . n 
A 1 130  HIS 130  130  130  HIS HIS A . n 
A 1 131  GLN 131  131  131  GLN GLN A . n 
A 1 132  GLU 132  132  132  GLU GLU A . n 
A 1 133  ALA 133  133  133  ALA ALA A . n 
A 1 134  MET 134  134  134  MET MET A . n 
A 1 135  ASN 135  135  135  ASN ASN A . n 
A 1 136  ALA 136  136  136  ALA ALA A . n 
A 1 137  SER 137  137  137  SER SER A . n 
A 1 138  THR 138  138  138  THR THR A . n 
A 1 139  PRO 139  139  139  PRO PRO A . n 
A 1 140  THR 140  140  140  THR THR A . n 
A 1 141  ILE 141  141  141  ILE ILE A . n 
A 1 142  ILE 142  142  142  ILE ILE A . n 
A 1 143  GLU 143  143  143  GLU GLU A . n 
A 1 144  SER 144  144  144  SER SER A . n 
A 1 145  TRP 145  145  145  TRP TRP A . n 
A 1 146  LEU 146  146  146  LEU LEU A . n 
A 1 147  ARG 147  147  147  ARG ARG A . n 
A 1 148  LYS 148  148  148  LYS LYS A . n 
A 1 149  GLN 149  149  149  GLN GLN A . n 
A 1 150  ILE 150  150  150  ILE ILE A . n 
A 1 151  TYR 151  151  151  TYR TYR A . n 
A 1 152  SER 152  152  152  SER SER A . n 
A 1 153  VAL 153  153  153  VAL VAL A . n 
A 1 154  ASP 154  154  154  ASP ASP A . n 
A 1 155  GLN 155  155  155  GLN GLN A . n 
A 1 156  THR 156  156  156  THR THR A . n 
A 1 157  ARG 157  157  157  ARG ARG A . n 
A 1 158  ARG 158  158  158  ARG ARG A . n 
A 1 159  ASN 159  159  159  ASN ASN A . n 
A 1 160  SER 160  160  160  SER SER A . n 
A 1 161  ILE 161  161  161  ILE ILE A . n 
A 1 162  SER 162  162  162  SER SER A . n 
A 1 163  LEU 163  163  163  LEU LEU A . n 
A 1 164  ARG 164  164  164  ARG ARG A . n 
A 1 165  GLU 165  165  165  GLU GLU A . n 
A 1 166  LEU 166  166  166  LEU LEU A . n 
A 1 167  LYS 167  167  167  LYS LYS A . n 
A 1 168  THR 168  168  168  THR THR A . n 
A 1 169  ILE 169  169  169  ILE ILE A . n 
A 1 170  LEU 170  170  170  LEU LEU A . n 
A 1 171  PRO 171  171  171  PRO PRO A . n 
A 1 172  LEU 172  172  172  LEU LEU A . n 
A 1 173  ILE 173  173  173  ILE ILE A . n 
A 1 174  ASN 174  174  174  ASN ASN A . n 
A 1 175  PHE 175  175  175  PHE PHE A . n 
A 1 176  LYS 176  176  176  LYS LYS A . n 
A 1 177  VAL 177  177  177  VAL VAL A . n 
A 1 178  SER 178  178  178  SER SER A . n 
A 1 179  SER 179  179  179  SER SER A . n 
A 1 180  ALA 180  180  180  ALA ALA A . n 
A 1 181  LYS 181  181  181  LYS LYS A . n 
A 1 182  PHE 182  182  182  PHE PHE A . n 
A 1 183  LEU 183  183  183  LEU LEU A . n 
A 1 184  LYS 184  184  184  LYS LYS A . n 
A 1 185  ASP 185  185  185  ASP ASP A . n 
A 1 186  LYS 186  186  186  LYS LYS A . n 
A 1 187  PHE 187  187  187  PHE PHE A . n 
A 1 188  VAL 188  188  188  VAL VAL A . n 
A 1 189  GLU 189  189  189  GLU GLU A . n 
A 1 190  ILE 190  190  190  ILE ILE A . n 
A 1 191  GLY 191  191  191  GLY GLY A . n 
A 1 192  ALA 192  192  192  ALA ALA A . n 
A 1 193  HIS 193  193  193  HIS HIS A . n 
A 1 194  LYS 194  194  194  LYS LYS A . n 
A 1 195  ASP 195  195  195  ASP ASP A . n 
A 1 196  GLU 196  196  196  GLU GLU A . n 
A 1 197  LEU 197  197  197  LEU LEU A . n 
A 1 198  SER 198  198  198  SER SER A . n 
A 1 199  PHE 199  199  199  PHE PHE A . n 
A 1 200  GLU 200  200  200  GLU GLU A . n 
A 1 201  GLN 201  201  201  GLN GLN A . n 
A 1 202  PHE 202  202  202  PHE PHE A . n 
A 1 203  HIS 203  203  203  HIS HIS A . n 
A 1 204  LEU 204  204  204  LEU LEU A . n 
A 1 205  PHE 205  205  205  PHE PHE A . n 
A 1 206  TYR 206  206  206  TYR TYR A . n 
A 1 207  LYS 207  207  207  LYS LYS A . n 
A 1 208  LYS 208  208  208  LYS LYS A . n 
A 1 209  LEU 209  209  209  LEU LEU A . n 
A 1 210  MET 210  210  210  MET MET A . n 
A 1 211  PHE 211  211  211  PHE PHE A . n 
A 1 212  GLU 212  212  212  GLU GLU A . n 
A 1 213  GLN 213  213  213  GLN GLN A . n 
A 1 214  GLN 214  214  214  GLN GLN A . n 
A 1 215  LYS 215  215  215  LYS LYS A . n 
A 1 216  SER 216  216  216  SER SER A . n 
A 1 217  ILE 217  217  217  ILE ILE A . n 
A 1 218  LEU 218  218  218  LEU LEU A . n 
A 1 219  ASP 219  219  219  ASP ASP A . n 
A 1 220  GLU 220  220  220  GLU GLU A . n 
A 1 221  PHE 221  221  221  PHE PHE A . n 
A 1 222  LYS 222  222  222  LYS LYS A . n 
A 1 223  LYS 223  223  223  LYS LYS A . n 
A 1 224  ASP 224  224  224  ASP ASP A . n 
A 1 225  SER 225  225  225  SER SER A . n 
A 1 226  SER 226  226  226  SER SER A . n 
A 1 227  VAL 227  227  227  VAL VAL A . n 
A 1 228  PHE 228  228  228  PHE PHE A . n 
A 1 229  ILE 229  229  229  ILE ILE A . n 
A 1 230  LEU 230  230  230  LEU LEU A . n 
A 1 231  GLY 231  231  231  GLY GLY A . n 
A 1 232  ASN 232  232  232  ASN ASN A . n 
A 1 233  THR 233  233  233  THR THR A . n 
A 1 234  ASP 234  234  234  ASP ASP A . n 
A 1 235  ARG 235  235  235  ARG ARG A . n 
A 1 236  PRO 236  236  236  PRO PRO A . n 
A 1 237  ASP 237  237  237  ASP ASP A . n 
A 1 238  ALA 238  238  238  ALA ALA A . n 
A 1 239  SER 239  239  239  SER SER A . n 
A 1 240  ALA 240  240  240  ALA ALA A . n 
A 1 241  VAL 241  241  241  VAL VAL A . n 
A 1 242  TYR 242  242  242  TYR TYR A . n 
A 1 243  LEU 243  243  243  LEU LEU A . n 
A 1 244  HIS 244  244  244  HIS HIS A . n 
A 1 245  ASP 245  245  245  ASP ASP A . n 
A 1 246  PHE 246  246  246  PHE PHE A . n 
A 1 247  GLN 247  247  247  GLN GLN A . n 
A 1 248  ARG 248  248  248  ARG ARG A . n 
A 1 249  PHE 249  249  249  PHE PHE A . n 
A 1 250  LEU 250  250  250  LEU LEU A . n 
A 1 251  ILE 251  251  251  ILE ILE A . n 
A 1 252  HIS 252  252  252  HIS HIS A . n 
A 1 253  GLU 253  253  253  GLU GLU A . n 
A 1 254  GLN 254  254  254  GLN GLN A . n 
A 1 255  GLN 255  255  255  GLN GLN A . n 
A 1 256  GLU 256  256  256  GLU GLU A . n 
A 1 257  HIS 257  257  257  HIS HIS A . n 
A 1 258  TRP 258  258  258  TRP TRP A . n 
A 1 259  ALA 259  259  259  ALA ALA A . n 
A 1 260  GLN 260  260  260  GLN GLN A . n 
A 1 261  ASP 261  261  261  ASP ASP A . n 
A 1 262  LEU 262  262  262  LEU LEU A . n 
A 1 263  ASN 263  263  263  ASN ASN A . n 
A 1 264  LYS 264  264  264  LYS LYS A . n 
A 1 265  VAL 265  265  265  VAL VAL A . n 
A 1 266  ARG 266  266  266  ARG ARG A . n 
A 1 267  GLU 267  267  267  GLU GLU A . n 
A 1 268  ARG 268  268  268  ARG ARG A . n 
A 1 269  MET 269  269  269  MET MET A . n 
A 1 270  THR 270  270  270  THR THR A . n 
A 1 271  LYS 271  271  271  LYS LYS A . n 
A 1 272  PHE 272  272  272  PHE PHE A . n 
A 1 273  ILE 273  273  273  ILE ILE A . n 
A 1 274  ASP 274  274  274  ASP ASP A . n 
A 1 275  ASP 275  275  275  ASP ASP A . n 
A 1 276  THR 276  276  276  THR THR A . n 
A 1 277  MET 277  277  277  MET MET A . n 
A 1 278  ARG 278  278  278  ARG ARG A . n 
A 1 279  GLU 279  279  279  GLU GLU A . n 
A 1 280  THR 280  280  280  THR THR A . n 
A 1 281  ALA 281  281  281  ALA ALA A . n 
A 1 282  GLU 282  282  282  GLU GLU A . n 
A 1 283  PRO 283  283  283  PRO PRO A . n 
A 1 284  PHE 284  284  284  PHE PHE A . n 
A 1 285  LEU 285  285  285  LEU LEU A . n 
A 1 286  PHE 286  286  286  PHE PHE A . n 
A 1 287  VAL 287  287  287  VAL VAL A . n 
A 1 288  ASP 288  288  288  ASP ASP A . n 
A 1 289  GLU 289  289  289  GLU GLU A . n 
A 1 290  PHE 290  290  290  PHE PHE A . n 
A 1 291  LEU 291  291  291  LEU LEU A . n 
A 1 292  THR 292  292  292  THR THR A . n 
A 1 293  TYR 293  293  293  TYR TYR A . n 
A 1 294  LEU 294  294  294  LEU LEU A . n 
A 1 295  PHE 295  295  295  PHE PHE A . n 
A 1 296  SER 296  296  296  SER SER A . n 
A 1 297  ARG 297  297  297  ARG ARG A . n 
A 1 298  GLU 298  298  298  GLU GLU A . n 
A 1 299  ASN 299  299  299  ASN ASN A . n 
A 1 300  SER 300  300  300  SER SER A . n 
A 1 301  ILE 301  301  301  ILE ILE A . n 
A 1 302  TRP 302  302  302  TRP TRP A . n 
A 1 303  ASP 303  303  303  ASP ASP A . n 
A 1 304  GLU 304  304  304  GLU GLU A . n 
A 1 305  LYS 305  305  305  LYS LYS A . n 
A 1 306  TYR 306  306  306  TYR TYR A . n 
A 1 307  ASP 307  307  307  ASP ASP A . n 
A 1 308  ALA 308  308  308  ALA ALA A . n 
A 1 309  VAL 309  309  309  VAL VAL A . n 
A 1 310  ASP 310  310  310  ASP ASP A . n 
A 1 311  MET 311  311  311  MET MET A . n 
A 1 312  GLN 312  312  312  GLN GLN A . n 
A 1 313  ASP 313  313  313  ASP ASP A . n 
A 1 314  MET 314  314  314  MET MET A . n 
A 1 315  ASN 315  315  315  ASN ASN A . n 
A 1 316  ASN 316  316  316  ASN ASN A . n 
A 1 317  PRO 317  317  317  PRO PRO A . n 
A 1 318  LEU 318  318  318  LEU LEU A . n 
A 1 319  SER 319  319  319  SER SER A . n 
A 1 320  HIS 320  320  320  HIS HIS A . n 
A 1 321  TYR 321  321  321  TYR TYR A . n 
A 1 322  TRP 322  322  322  TRP TRP A . n 
A 1 323  ILE 323  323  323  ILE ILE A . n 
A 1 324  SER 324  324  324  SER SER A . n 
A 1 325  SER 325  325  325  SER SER A . n 
A 1 326  SER 326  326  326  SER SER A . n 
A 1 327  HIS 327  327  327  HIS HIS A . n 
A 1 328  ASN 328  328  328  ASN ASN A . n 
A 1 329  THR 329  329  329  THR THR A . n 
A 1 330  TYR 330  330  330  TYR TYR A . n 
A 1 331  LEU 331  331  331  LEU LEU A . n 
A 1 332  THR 332  332  332  THR THR A . n 
A 1 333  GLY 333  333  333  GLY GLY A . n 
A 1 334  ASP 334  334  334  ASP ASP A . n 
A 1 335  GLN 335  335  335  GLN GLN A . n 
A 1 336  LEU 336  336  336  LEU LEU A . n 
A 1 337  ARG 337  337  337  ARG ARG A . n 
A 1 338  SER 338  338  338  SER SER A . n 
A 1 339  GLU 339  339  339  GLU GLU A . n 
A 1 340  SER 340  340  340  SER SER A . n 
A 1 341  SER 341  341  341  SER SER A . n 
A 1 342  PRO 342  342  342  PRO PRO A . n 
A 1 343  GLU 343  343  343  GLU GLU A . n 
A 1 344  ALA 344  344  344  ALA ALA A . n 
A 1 345  TYR 345  345  345  TYR TYR A . n 
A 1 346  ILE 346  346  346  ILE ILE A . n 
A 1 347  ARG 347  347  347  ARG ARG A . n 
A 1 348  CYS 348  348  348  CYS CYS A . n 
A 1 349  LEU 349  349  349  LEU LEU A . n 
A 1 350  ARG 350  350  350  ARG ARG A . n 
A 1 351  MET 351  351  351  MET MET A . n 
A 1 352  GLY 352  352  352  GLY GLY A . n 
A 1 353  CYS 353  353  353  CYS CYS A . n 
A 1 354  ARG 354  354  354  ARG ARG A . n 
A 1 355  CYS 355  355  355  CYS CYS A . n 
A 1 356  ILE 356  356  356  ILE ILE A . n 
A 1 357  GLU 357  357  357  GLU GLU A . n 
A 1 358  LEU 358  358  358  LEU LEU A . n 
A 1 359  ASP 359  359  359  ASP ASP A . n 
A 1 360  CYS 360  360  360  CYS CYS A . n 
A 1 361  TRP 361  361  361  TRP TRP A . n 
A 1 362  ASP 362  362  362  ASP ASP A . n 
A 1 363  GLY 363  363  363  GLY GLY A . n 
A 1 364  PRO 364  364  364  PRO PRO A . n 
A 1 365  ASP 365  365  365  ASP ASP A . n 
A 1 366  GLY 366  366  366  GLY GLY A . n 
A 1 367  LYS 367  367  367  LYS LYS A . n 
A 1 368  PRO 368  368  368  PRO PRO A . n 
A 1 369  VAL 369  369  369  VAL VAL A . n 
A 1 370  ILE 370  370  370  ILE ILE A . n 
A 1 371  TYR 371  371  371  TYR TYR A . n 
A 1 372  HIS 372  372  372  HIS HIS A . n 
A 1 373  GLY 373  373  373  GLY GLY A . n 
A 1 374  TRP 374  374  374  TRP TRP A . n 
A 1 375  THR 375  375  375  THR THR A . n 
A 1 376  ARG 376  376  376  ARG ARG A . n 
A 1 377  THR 377  377  377  THR THR A . n 
A 1 378  THR 378  378  378  THR THR A . n 
A 1 379  LYS 379  379  379  LYS LYS A . n 
A 1 380  ILE 380  380  380  ILE ILE A . n 
A 1 381  LYS 381  381  381  LYS LYS A . n 
A 1 382  PHE 382  382  382  PHE PHE A . n 
A 1 383  ASP 383  383  383  ASP ASP A . n 
A 1 384  ASP 384  384  384  ASP ASP A . n 
A 1 385  VAL 385  385  385  VAL VAL A . n 
A 1 386  VAL 386  386  386  VAL VAL A . n 
A 1 387  GLN 387  387  387  GLN GLN A . n 
A 1 388  ALA 388  388  388  ALA ALA A . n 
A 1 389  ILE 389  389  389  ILE ILE A . n 
A 1 390  LYS 390  390  390  LYS LYS A . n 
A 1 391  ASP 391  391  391  ASP ASP A . n 
A 1 392  HIS 392  392  392  HIS HIS A . n 
A 1 393  ALA 393  393  393  ALA ALA A . n 
A 1 394  PHE 394  394  394  PHE PHE A . n 
A 1 395  VAL 395  395  395  VAL VAL A . n 
A 1 396  THR 396  396  396  THR THR A . n 
A 1 397  SER 397  397  397  SER SER A . n 
A 1 398  SER 398  398  398  SER SER A . n 
A 1 399  PHE 399  399  399  PHE PHE A . n 
A 1 400  PRO 400  400  400  PRO PRO A . n 
A 1 401  VAL 401  401  401  VAL VAL A . n 
A 1 402  ILE 402  402  402  ILE ILE A . n 
A 1 403  LEU 403  403  403  LEU LEU A . n 
A 1 404  SER 404  404  404  SER SER A . n 
A 1 405  ILE 405  405  405  ILE ILE A . n 
A 1 406  GLU 406  406  406  GLU GLU A . n 
A 1 407  GLU 407  407  407  GLU GLU A . n 
A 1 408  HIS 408  408  408  HIS HIS A . n 
A 1 409  CYS 409  409  409  CYS CYS A . n 
A 1 410  SER 410  410  410  SER SER A . n 
A 1 411  VAL 411  411  411  VAL VAL A . n 
A 1 412  GLU 412  412  412  GLU GLU A . n 
A 1 413  GLN 413  413  413  GLN GLN A . n 
A 1 414  GLN 414  414  414  GLN GLN A . n 
A 1 415  ARG 415  415  415  ARG ARG A . n 
A 1 416  HIS 416  416  416  HIS HIS A . n 
A 1 417  MET 417  417  417  MET MET A . n 
A 1 418  ALA 418  418  418  ALA ALA A . n 
A 1 419  LYS 419  419  419  LYS LYS A . n 
A 1 420  ALA 420  420  420  ALA ALA A . n 
A 1 421  PHE 421  421  421  PHE PHE A . n 
A 1 422  LYS 422  422  422  LYS LYS A . n 
A 1 423  GLU 423  423  423  GLU GLU A . n 
A 1 424  VAL 424  424  424  VAL VAL A . n 
A 1 425  PHE 425  425  425  PHE PHE A . n 
A 1 426  GLY 426  426  426  GLY GLY A . n 
A 1 427  ASP 427  427  427  ASP ASP A . n 
A 1 428  LEU 428  428  428  LEU LEU A . n 
A 1 429  LEU 429  429  429  LEU LEU A . n 
A 1 430  LEU 430  430  430  LEU LEU A . n 
A 1 431  THR 431  431  431  THR THR A . n 
A 1 432  LYS 432  432  432  LYS LYS A . n 
A 1 433  PRO 433  433  433  PRO PRO A . n 
A 1 434  THR 434  434  434  THR THR A . n 
A 1 435  GLU 435  435  435  GLU GLU A . n 
A 1 436  ALA 436  436  436  ALA ALA A . n 
A 1 437  SER 437  437  437  SER SER A . n 
A 1 438  ALA 438  438  438  ALA ALA A . n 
A 1 439  ASP 439  439  439  ASP ASP A . n 
A 1 440  GLN 440  440  440  GLN GLN A . n 
A 1 441  LEU 441  441  441  LEU LEU A . n 
A 1 442  PRO 442  442  442  PRO PRO A . n 
A 1 443  SER 443  443  443  SER SER A . n 
A 1 444  PRO 444  444  444  PRO PRO A . n 
A 1 445  SER 445  445  445  SER SER A . n 
A 1 446  GLN 446  446  446  GLN GLN A . n 
A 1 447  LEU 447  447  447  LEU LEU A . n 
A 1 448  ARG 448  448  448  ARG ARG A . n 
A 1 449  GLU 449  449  449  GLU GLU A . n 
A 1 450  LYS 450  450  450  LYS LYS A . n 
A 1 451  ILE 451  451  451  ILE ILE A . n 
A 1 452  ILE 452  452  452  ILE ILE A . n 
A 1 453  ILE 453  453  453  ILE ILE A . n 
A 1 454  LYS 454  454  454  LYS LYS A . n 
A 1 455  HIS 455  455  455  HIS HIS A . n 
A 1 456  LYS 456  456  456  LYS LYS A . n 
A 1 457  LYS 457  457  457  LYS LYS A . n 
A 1 458  LEU 458  458  458  LEU LEU A . n 
A 1 459  GLY 459  459  459  GLY GLY A . n 
A 1 460  PRO 460  460  ?    ?   ?   A . n 
A 1 461  ARG 461  461  ?    ?   ?   A . n 
A 1 462  GLY 462  462  ?    ?   ?   A . n 
A 1 463  ASP 463  463  ?    ?   ?   A . n 
A 1 464  VAL 464  464  ?    ?   ?   A . n 
A 1 465  ASP 465  465  ?    ?   ?   A . n 
A 1 466  VAL 466  466  ?    ?   ?   A . n 
A 1 467  ASN 467  467  ?    ?   ?   A . n 
A 1 468  MET 468  468  ?    ?   ?   A . n 
A 1 469  GLU 469  469  ?    ?   ?   A . n 
A 1 470  ASP 470  470  ?    ?   ?   A . n 
A 1 471  LYS 471  471  ?    ?   ?   A . n 
A 1 472  LYS 472  472  ?    ?   ?   A . n 
A 1 473  ASP 473  473  ?    ?   ?   A . n 
A 1 474  GLU 474  474  ?    ?   ?   A . n 
A 1 475  HIS 475  475  475  HIS HIS A . n 
A 1 476  LYS 476  476  476  LYS LYS A . n 
A 1 477  GLN 477  477  477  GLN GLN A . n 
A 1 478  GLN 478  478  478  GLN GLN A . n 
A 1 479  GLY 479  479  479  GLY GLY A . n 
A 1 480  GLU 480  480  480  GLU GLU A . n 
A 1 481  LEU 481  481  481  LEU LEU A . n 
A 1 482  TYR 482  482  482  TYR TYR A . n 
A 1 483  MET 483  483  483  MET MET A . n 
A 1 484  TRP 484  484  484  TRP TRP A . n 
A 1 485  ASP 485  485  485  ASP ASP A . n 
A 1 486  SER 486  486  486  SER SER A . n 
A 1 487  ILE 487  487  487  ILE ILE A . n 
A 1 488  ASP 488  488  488  ASP ASP A . n 
A 1 489  GLN 489  489  489  GLN GLN A . n 
A 1 490  LYS 490  490  490  LYS LYS A . n 
A 1 491  TRP 491  491  491  TRP TRP A . n 
A 1 492  THR 492  492  492  THR THR A . n 
A 1 493  ARG 493  493  493  ARG ARG A . n 
A 1 494  HIS 494  494  494  HIS HIS A . n 
A 1 495  TYR 495  495  495  TYR TYR A . n 
A 1 496  CYS 496  496  496  CYS CYS A . n 
A 1 497  ALA 497  497  497  ALA ALA A . n 
A 1 498  ILE 498  498  498  ILE ILE A . n 
A 1 499  ALA 499  499  499  ALA ALA A . n 
A 1 500  ASP 500  500  500  ASP ASP A . n 
A 1 501  ALA 501  501  501  ALA ALA A . n 
A 1 502  LYS 502  502  502  LYS LYS A . n 
A 1 503  LEU 503  503  503  LEU LEU A . n 
A 1 504  SER 504  504  504  SER SER A . n 
A 1 505  PHE 505  505  505  PHE PHE A . n 
A 1 506  SER 506  506  506  SER SER A . n 
A 1 507  ASP 507  507  507  ASP ASP A . n 
A 1 508  ASP 508  508  508  ASP ASP A . n 
A 1 509  ILE 509  509  509  ILE ILE A . n 
A 1 510  GLU 510  510  510  GLU GLU A . n 
A 1 511  GLN 511  511  ?    ?   ?   A . n 
A 1 512  THR 512  512  ?    ?   ?   A . n 
A 1 513  MET 513  513  ?    ?   ?   A . n 
A 1 514  GLU 514  514  ?    ?   ?   A . n 
A 1 515  GLU 515  515  ?    ?   ?   A . n 
A 1 516  GLU 516  516  ?    ?   ?   A . n 
A 1 517  VAL 517  517  ?    ?   ?   A . n 
A 1 518  PRO 518  518  ?    ?   ?   A . n 
A 1 519  GLN 519  519  ?    ?   ?   A . n 
A 1 520  ASP 520  520  ?    ?   ?   A . n 
A 1 521  ILE 521  521  ?    ?   ?   A . n 
A 1 522  PRO 522  522  ?    ?   ?   A . n 
A 1 523  PRO 523  523  ?    ?   ?   A . n 
A 1 524  THR 524  524  ?    ?   ?   A . n 
A 1 525  GLU 525  525  ?    ?   ?   A . n 
A 1 526  LEU 526  526  526  LEU LEU A . n 
A 1 527  HIS 527  527  527  HIS HIS A . n 
A 1 528  PHE 528  528  528  PHE PHE A . n 
A 1 529  GLY 529  529  529  GLY GLY A . n 
A 1 530  GLU 530  530  530  GLU GLU A . n 
A 1 531  LYS 531  531  531  LYS LYS A . n 
A 1 532  TRP 532  532  532  TRP TRP A . n 
A 1 533  PHE 533  533  533  PHE PHE A . n 
A 1 534  HIS 534  534  534  HIS HIS A . n 
A 1 535  LYS 535  535  535  LYS LYS A . n 
A 1 536  LYS 536  536  536  LYS LYS A . n 
A 1 537  VAL 537  537  537  VAL VAL A . n 
A 1 538  GLU 538  538  538  GLU GLU A . n 
A 1 539  LYS 539  539  539  LYS LYS A . n 
A 1 540  ARG 540  540  540  ARG ARG A . n 
A 1 541  THR 541  541  541  THR THR A . n 
A 1 542  SER 542  542  542  SER SER A . n 
A 1 543  ALA 543  543  543  ALA ALA A . n 
A 1 544  GLU 544  544  544  GLU GLU A . n 
A 1 545  LYS 545  545  545  LYS LYS A . n 
A 1 546  LEU 546  546  546  LEU LEU A . n 
A 1 547  LEU 547  547  547  LEU LEU A . n 
A 1 548  GLN 548  548  548  GLN GLN A . n 
A 1 549  GLU 549  549  549  GLU GLU A . n 
A 1 550  TYR 550  550  550  TYR TYR A . n 
A 1 551  CYS 551  551  551  CYS CYS A . n 
A 1 552  MET 552  552  552  MET MET A . n 
A 1 553  GLU 553  553  553  GLU GLU A . n 
A 1 554  THR 554  554  554  THR THR A . n 
A 1 555  GLY 555  555  555  GLY GLY A . n 
A 1 556  GLY 556  556  556  GLY GLY A . n 
A 1 557  LYS 557  557  557  LYS LYS A . n 
A 1 558  ASP 558  558  558  ASP ASP A . n 
A 1 559  GLY 559  559  559  GLY GLY A . n 
A 1 560  THR 560  560  560  THR THR A . n 
A 1 561  PHE 561  561  561  PHE PHE A . n 
A 1 562  LEU 562  562  562  LEU LEU A . n 
A 1 563  VAL 563  563  563  VAL VAL A . n 
A 1 564  ARG 564  564  564  ARG ARG A . n 
A 1 565  GLU 565  565  565  GLU GLU A . n 
A 1 566  SER 566  566  566  SER SER A . n 
A 1 567  GLU 567  567  567  GLU GLU A . n 
A 1 568  THR 568  568  568  THR THR A . n 
A 1 569  PHE 569  569  569  PHE PHE A . n 
A 1 570  PRO 570  570  570  PRO PRO A . n 
A 1 571  ASN 571  571  571  ASN ASN A . n 
A 1 572  ASP 572  572  572  ASP ASP A . n 
A 1 573  TYR 573  573  573  TYR TYR A . n 
A 1 574  THR 574  574  574  THR THR A . n 
A 1 575  LEU 575  575  575  LEU LEU A . n 
A 1 576  SER 576  576  576  SER SER A . n 
A 1 577  PHE 577  577  577  PHE PHE A . n 
A 1 578  TRP 578  578  578  TRP TRP A . n 
A 1 579  ARG 579  579  579  ARG ARG A . n 
A 1 580  SER 580  580  580  SER SER A . n 
A 1 581  GLY 581  581  581  GLY GLY A . n 
A 1 582  ARG 582  582  582  ARG ARG A . n 
A 1 583  VAL 583  583  583  VAL VAL A . n 
A 1 584  GLN 584  584  584  GLN GLN A . n 
A 1 585  HIS 585  585  585  HIS HIS A . n 
A 1 586  CYS 586  586  586  CYS CYS A . n 
A 1 587  ARG 587  587  587  ARG ARG A . n 
A 1 588  ILE 588  588  588  ILE ILE A . n 
A 1 589  ARG 589  589  589  ARG ARG A . n 
A 1 590  SER 590  590  590  SER SER A . n 
A 1 591  THR 591  591  591  THR THR A . n 
A 1 592  MET 592  592  592  MET MET A . n 
A 1 593  GLU 593  593  593  GLU GLU A . n 
A 1 594  GLY 594  594  594  GLY GLY A . n 
A 1 595  GLY 595  595  595  GLY GLY A . n 
A 1 596  THR 596  596  596  THR THR A . n 
A 1 597  LEU 597  597  597  LEU LEU A . n 
A 1 598  LYS 598  598  598  LYS LYS A . n 
A 1 599  TYR 599  599  599  TYR TYR A . n 
A 1 600  TYR 600  600  600  TYR TYR A . n 
A 1 601  LEU 601  601  601  LEU LEU A . n 
A 1 602  THR 602  602  602  THR THR A . n 
A 1 603  ASP 603  603  603  ASP ASP A . n 
A 1 604  ASN 604  604  604  ASN ASN A . n 
A 1 605  LEU 605  605  605  LEU LEU A . n 
A 1 606  THR 606  606  606  THR THR A . n 
A 1 607  PHE 607  607  607  PHE PHE A . n 
A 1 608  SER 608  608  608  SER SER A . n 
A 1 609  SER 609  609  609  SER SER A . n 
A 1 610  ILE 610  610  610  ILE ILE A . n 
A 1 611  TYR 611  611  611  TYR TYR A . n 
A 1 612  ALA 612  612  612  ALA ALA A . n 
A 1 613  LEU 613  613  613  LEU LEU A . n 
A 1 614  ILE 614  614  614  ILE ILE A . n 
A 1 615  GLN 615  615  615  GLN GLN A . n 
A 1 616  HIS 616  616  616  HIS HIS A . n 
A 1 617  TYR 617  617  617  TYR TYR A . n 
A 1 618  ARG 618  618  618  ARG ARG A . n 
A 1 619  GLU 619  619  619  GLU GLU A . n 
A 1 620  THR 620  620  620  THR THR A . n 
A 1 621  HIS 621  621  621  HIS HIS A . n 
A 1 622  LEU 622  622  622  LEU LEU A . n 
A 1 623  ARG 623  623  623  ARG ARG A . n 
A 1 624  CYS 624  624  624  CYS CYS A . n 
A 1 625  ALA 625  625  625  ALA ALA A . n 
A 1 626  GLU 626  626  626  GLU GLU A . n 
A 1 627  PHE 627  627  627  PHE PHE A . n 
A 1 628  GLU 628  628  628  GLU GLU A . n 
A 1 629  LEU 629  629  629  LEU LEU A . n 
A 1 630  ARG 630  630  630  ARG ARG A . n 
A 1 631  LEU 631  631  631  LEU LEU A . n 
A 1 632  THR 632  632  632  THR THR A . n 
A 1 633  ASP 633  633  633  ASP ASP A . n 
A 1 634  PRO 634  634  634  PRO PRO A . n 
A 1 635  VAL 635  635  635  VAL VAL A . n 
A 1 636  PRO 636  636  636  PRO PRO A . n 
A 1 637  ASN 637  637  637  ASN ASN A . n 
A 1 638  PRO 638  638  638  PRO PRO A . n 
A 1 639  ASN 639  639  639  ASN ASN A . n 
A 1 640  PRO 640  640  640  PRO PRO A . n 
A 1 641  HIS 641  641  641  HIS HIS A . n 
A 1 642  GLU 642  642  642  GLU GLU A . n 
A 1 643  SER 643  643  643  SER SER A . n 
A 1 644  LYS 644  644  644  LYS LYS A . n 
A 1 645  PRO 645  645  645  PRO PRO A . n 
A 1 646  TRP 646  646  646  TRP TRP A . n 
A 1 647  TYR 647  647  647  TYR TYR A . n 
A 1 648  TYR 648  648  648  TYR TYR A . n 
A 1 649  ASP 649  649  649  ASP ASP A . n 
A 1 650  SER 650  650  650  SER SER A . n 
A 1 651  LEU 651  651  651  LEU LEU A . n 
A 1 652  SER 652  652  652  SER SER A . n 
A 1 653  ARG 653  653  653  ARG ARG A . n 
A 1 654  GLY 654  654  654  GLY GLY A . n 
A 1 655  GLU 655  655  655  GLU GLU A . n 
A 1 656  ALA 656  656  656  ALA ALA A . n 
A 1 657  GLU 657  657  657  GLU GLU A . n 
A 1 658  ASP 658  658  658  ASP ASP A . n 
A 1 659  MET 659  659  659  MET MET A . n 
A 1 660  LEU 660  660  660  LEU LEU A . n 
A 1 661  MET 661  661  661  MET MET A . n 
A 1 662  ARG 662  662  662  ARG ARG A . n 
A 1 663  ILE 663  663  663  ILE ILE A . n 
A 1 664  PRO 664  664  664  PRO PRO A . n 
A 1 665  ARG 665  665  665  ARG ARG A . n 
A 1 666  ASP 666  666  666  ASP ASP A . n 
A 1 667  GLY 667  667  667  GLY GLY A . n 
A 1 668  ALA 668  668  668  ALA ALA A . n 
A 1 669  PHE 669  669  669  PHE PHE A . n 
A 1 670  LEU 670  670  670  LEU LEU A . n 
A 1 671  ILE 671  671  671  ILE ILE A . n 
A 1 672  ARG 672  672  672  ARG ARG A . n 
A 1 673  LYS 673  673  673  LYS LYS A . n 
A 1 674  ARG 674  674  674  ARG ARG A . n 
A 1 675  GLU 675  675  675  GLU GLU A . n 
A 1 676  GLY 676  676  676  GLY GLY A . n 
A 1 677  SER 677  677  677  SER SER A . n 
A 1 678  ASP 678  678  678  ASP ASP A . n 
A 1 679  SER 679  679  679  SER SER A . n 
A 1 680  TYR 680  680  680  TYR TYR A . n 
A 1 681  ALA 681  681  681  ALA ALA A . n 
A 1 682  ILE 682  682  682  ILE ILE A . n 
A 1 683  THR 683  683  683  THR THR A . n 
A 1 684  PHE 684  684  684  PHE PHE A . n 
A 1 685  ARG 685  685  685  ARG ARG A . n 
A 1 686  ALA 686  686  686  ALA ALA A . n 
A 1 687  ARG 687  687  687  ARG ARG A . n 
A 1 688  GLY 688  688  688  GLY GLY A . n 
A 1 689  LYS 689  689  689  LYS LYS A . n 
A 1 690  VAL 690  690  690  VAL VAL A . n 
A 1 691  LYS 691  691  691  LYS LYS A . n 
A 1 692  HIS 692  692  692  HIS HIS A . n 
A 1 693  CYS 693  693  693  CYS CYS A . n 
A 1 694  ARG 694  694  694  ARG ARG A . n 
A 1 695  ILE 695  695  695  ILE ILE A . n 
A 1 696  ASN 696  696  696  ASN ASN A . n 
A 1 697  ARG 697  697  697  ARG ARG A . n 
A 1 698  ASP 698  698  698  ASP ASP A . n 
A 1 699  GLY 699  699  699  GLY GLY A . n 
A 1 700  ARG 700  700  700  ARG ARG A . n 
A 1 701  HIS 701  701  701  HIS HIS A . n 
A 1 702  PHE 702  702  702  PHE PHE A . n 
A 1 703  VAL 703  703  703  VAL VAL A . n 
A 1 704  LEU 704  704  704  LEU LEU A . n 
A 1 705  GLY 705  705  705  GLY GLY A . n 
A 1 706  THR 706  706  706  THR THR A . n 
A 1 707  SER 707  707  707  SER SER A . n 
A 1 708  ALA 708  708  708  ALA ALA A . n 
A 1 709  TYR 709  709  709  TYR TYR A . n 
A 1 710  PHE 710  710  710  PHE PHE A . n 
A 1 711  GLU 711  711  711  GLU GLU A . n 
A 1 712  SER 712  712  712  SER SER A . n 
A 1 713  LEU 713  713  713  LEU LEU A . n 
A 1 714  VAL 714  714  714  VAL VAL A . n 
A 1 715  GLU 715  715  715  GLU GLU A . n 
A 1 716  LEU 716  716  716  LEU LEU A . n 
A 1 717  VAL 717  717  717  VAL VAL A . n 
A 1 718  SER 718  718  718  SER SER A . n 
A 1 719  TYR 719  719  719  TYR TYR A . n 
A 1 720  TYR 720  720  720  TYR TYR A . n 
A 1 721  GLU 721  721  721  GLU GLU A . n 
A 1 722  LYS 722  722  722  LYS LYS A . n 
A 1 723  HIS 723  723  723  HIS HIS A . n 
A 1 724  SER 724  724  724  SER SER A . n 
A 1 725  LEU 725  725  725  LEU LEU A . n 
A 1 726  TYR 726  726  726  TYR TYR A . n 
A 1 727  ARG 727  727  727  ARG ARG A . n 
A 1 728  LYS 728  728  728  LYS LYS A . n 
A 1 729  MET 729  729  729  MET MET A . n 
A 1 730  ARG 730  730  730  ARG ARG A . n 
A 1 731  LEU 731  731  731  LEU LEU A . n 
A 1 732  ARG 732  732  732  ARG ARG A . n 
A 1 733  TYR 733  733  733  TYR TYR A . n 
A 1 734  PRO 734  734  734  PRO PRO A . n 
A 1 735  VAL 735  735  735  VAL VAL A . n 
A 1 736  THR 736  736  736  THR THR A . n 
A 1 737  PRO 737  737  737  PRO PRO A . n 
A 1 738  GLU 738  738  738  GLU GLU A . n 
A 1 739  LEU 739  739  739  LEU LEU A . n 
A 1 740  LEU 740  740  740  LEU LEU A . n 
A 1 741  GLU 741  741  741  GLU GLU A . n 
A 1 742  ARG 742  742  742  ARG ARG A . n 
A 1 743  TYR 743  743  743  TYR TYR A . n 
A 1 744  ASN 744  744  ?    ?   ?   A . n 
A 1 745  MET 745  745  ?    ?   ?   A . n 
A 1 746  GLU 746  746  ?    ?   ?   A . n 
A 1 747  ARG 747  747  ?    ?   ?   A . n 
A 1 748  ASP 748  748  ?    ?   ?   A . n 
A 1 749  ILE 749  749  ?    ?   ?   A . n 
A 1 750  ASN 750  750  ?    ?   ?   A . n 
A 1 751  SER 751  751  ?    ?   ?   A . n 
A 1 752  LEU 752  752  ?    ?   ?   A . n 
A 1 753  TYR 753  753  ?    ?   ?   A . n 
A 1 754  ASP 754  754  ?    ?   ?   A . n 
A 1 755  VAL 755  755  ?    ?   ?   A . n 
A 1 756  SER 756  756  ?    ?   ?   A . n 
A 1 757  ARG 757  757  ?    ?   ?   A . n 
A 1 758  MET 758  758  ?    ?   ?   A . n 
A 1 759  TYR 759  759  ?    ?   ?   A . n 
A 1 760  VAL 760  760  ?    ?   ?   A . n 
A 1 761  ASP 761  761  ?    ?   ?   A . n 
A 1 762  PRO 762  762  ?    ?   ?   A . n 
A 1 763  SER 763  763  ?    ?   ?   A . n 
A 1 764  GLU 764  764  ?    ?   ?   A . n 
A 1 765  ILE 765  765  ?    ?   ?   A . n 
A 1 766  ASN 766  766  ?    ?   ?   A . n 
A 1 767  PRO 767  767  ?    ?   ?   A . n 
A 1 768  SER 768  768  ?    ?   ?   A . n 
A 1 769  MET 769  769  ?    ?   ?   A . n 
A 1 770  PRO 770  770  ?    ?   ?   A . n 
A 1 771  GLN 771  771  ?    ?   ?   A . n 
A 1 772  ARG 772  772  ?    ?   ?   A . n 
A 1 773  THR 773  773  ?    ?   ?   A . n 
A 1 774  VAL 774  774  ?    ?   ?   A . n 
A 1 775  LYS 775  775  ?    ?   ?   A . n 
A 1 776  ALA 776  776  ?    ?   ?   A . n 
A 1 777  LEU 777  777  ?    ?   ?   A . n 
A 1 778  TYR 778  778  ?    ?   ?   A . n 
A 1 779  ASP 779  779  ?    ?   ?   A . n 
A 1 780  TYR 780  780  ?    ?   ?   A . n 
A 1 781  LYS 781  781  ?    ?   ?   A . n 
A 1 782  ALA 782  782  ?    ?   ?   A . n 
A 1 783  LYS 783  783  ?    ?   ?   A . n 
A 1 784  ARG 784  784  ?    ?   ?   A . n 
A 1 785  SER 785  785  ?    ?   ?   A . n 
A 1 786  ASP 786  786  ?    ?   ?   A . n 
A 1 787  GLU 787  787  ?    ?   ?   A . n 
A 1 788  LEU 788  788  ?    ?   ?   A . n 
A 1 789  SER 789  789  ?    ?   ?   A . n 
A 1 790  PHE 790  790  ?    ?   ?   A . n 
A 1 791  CYS 791  791  ?    ?   ?   A . n 
A 1 792  ARG 792  792  ?    ?   ?   A . n 
A 1 793  GLY 793  793  ?    ?   ?   A . n 
A 1 794  ALA 794  794  ?    ?   ?   A . n 
A 1 795  LEU 795  795  ?    ?   ?   A . n 
A 1 796  ILE 796  796  ?    ?   ?   A . n 
A 1 797  HIS 797  797  ?    ?   ?   A . n 
A 1 798  ASN 798  798  ?    ?   ?   A . n 
A 1 799  VAL 799  799  ?    ?   ?   A . n 
A 1 800  SER 800  800  ?    ?   ?   A . n 
A 1 801  LYS 801  801  ?    ?   ?   A . n 
A 1 802  GLU 802  802  ?    ?   ?   A . n 
A 1 803  PRO 803  803  ?    ?   ?   A . n 
A 1 804  GLY 804  804  ?    ?   ?   A . n 
A 1 805  GLY 805  805  ?    ?   ?   A . n 
A 1 806  TRP 806  806  ?    ?   ?   A . n 
A 1 807  TRP 807  807  ?    ?   ?   A . n 
A 1 808  LYS 808  808  ?    ?   ?   A . n 
A 1 809  GLY 809  809  ?    ?   ?   A . n 
A 1 810  ASP 810  810  ?    ?   ?   A . n 
A 1 811  TYR 811  811  ?    ?   ?   A . n 
A 1 812  GLY 812  812  ?    ?   ?   A . n 
A 1 813  THR 813  813  ?    ?   ?   A . n 
A 1 814  ARG 814  814  ?    ?   ?   A . n 
A 1 815  ILE 815  815  ?    ?   ?   A . n 
A 1 816  GLN 816  816  ?    ?   ?   A . n 
A 1 817  GLN 817  817  ?    ?   ?   A . n 
A 1 818  TYR 818  818  ?    ?   ?   A . n 
A 1 819  PHE 819  819  ?    ?   ?   A . n 
A 1 820  PRO 820  820  ?    ?   ?   A . n 
A 1 821  SER 821  821  ?    ?   ?   A . n 
A 1 822  ASN 822  822  ?    ?   ?   A . n 
A 1 823  TYR 823  823  ?    ?   ?   A . n 
A 1 824  VAL 824  824  ?    ?   ?   A . n 
A 1 825  GLU 825  825  ?    ?   ?   A . n 
A 1 826  ASP 826  826  ?    ?   ?   A . n 
A 1 827  ILE 827  827  ?    ?   ?   A . n 
A 1 828  SER 828  828  ?    ?   ?   A . n 
A 1 829  THR 829  829  ?    ?   ?   A . n 
A 1 830  ALA 830  830  ?    ?   ?   A . n 
A 1 831  ASP 831  831  ?    ?   ?   A . n 
A 1 832  PHE 832  832  ?    ?   ?   A . n 
A 1 833  GLU 833  833  ?    ?   ?   A . n 
A 1 834  GLU 834  834  834  GLU GLU A . n 
A 1 835  LEU 835  835  835  LEU LEU A . n 
A 1 836  GLU 836  836  836  GLU GLU A . n 
A 1 837  LYS 837  837  837  LYS LYS A . n 
A 1 838  GLN 838  838  838  GLN GLN A . n 
A 1 839  ILE 839  839  839  ILE ILE A . n 
A 1 840  ILE 840  840  840  ILE ILE A . n 
A 1 841  GLU 841  841  841  GLU GLU A . n 
A 1 842  ASP 842  842  842  ASP ASP A . n 
A 1 843  ASN 843  843  843  ASN ASN A . n 
A 1 844  PRO 844  844  844  PRO PRO A . n 
A 1 845  LEU 845  845  845  LEU LEU A . n 
A 1 846  GLY 846  846  846  GLY GLY A . n 
A 1 847  SER 847  847  847  SER SER A . n 
A 1 848  LEU 848  848  848  LEU LEU A . n 
A 1 849  CYS 849  849  849  CYS CYS A . n 
A 1 850  ARG 850  850  850  ARG ARG A . n 
A 1 851  GLY 851  851  851  GLY GLY A . n 
A 1 852  ILE 852  852  852  ILE ILE A . n 
A 1 853  LEU 853  853  853  LEU LEU A . n 
A 1 854  ASP 854  854  854  ASP ASP A . n 
A 1 855  LEU 855  855  855  LEU LEU A . n 
A 1 856  ASN 856  856  856  ASN ASN A . n 
A 1 857  THR 857  857  857  THR THR A . n 
A 1 858  TYR 858  858  858  TYR TYR A . n 
A 1 859  ASN 859  859  859  ASN ASN A . n 
A 1 860  VAL 860  860  860  VAL VAL A . n 
A 1 861  VAL 861  861  861  VAL VAL A . n 
A 1 862  LYS 862  862  862  LYS LYS A . n 
A 1 863  ALA 863  863  863  ALA ALA A . n 
A 1 864  PRO 864  864  864  PRO PRO A . n 
A 1 865  GLN 865  865  865  GLN GLN A . n 
A 1 866  GLY 866  866  866  GLY GLY A . n 
A 1 867  LYS 867  867  867  LYS LYS A . n 
A 1 868  ASN 868  868  868  ASN ASN A . n 
A 1 869  GLN 869  869  869  GLN GLN A . n 
A 1 870  LYS 870  870  870  LYS LYS A . n 
A 1 871  SER 871  871  871  SER SER A . n 
A 1 872  PHE 872  872  872  PHE PHE A . n 
A 1 873  VAL 873  873  873  VAL VAL A . n 
A 1 874  PHE 874  874  874  PHE PHE A . n 
A 1 875  ILE 875  875  875  ILE ILE A . n 
A 1 876  LEU 876  876  876  LEU LEU A . n 
A 1 877  GLU 877  877  877  GLU GLU A . n 
A 1 878  PRO 878  878  878  PRO PRO A . n 
A 1 879  LYS 879  879  879  LYS LYS A . n 
A 1 880  GLN 880  880  880  GLN GLN A . n 
A 1 881  GLN 881  881  881  GLN GLN A . n 
A 1 882  GLY 882  882  882  GLY GLY A . n 
A 1 883  ASP 883  883  883  ASP ASP A . n 
A 1 884  PRO 884  884  884  PRO PRO A . n 
A 1 885  PRO 885  885  885  PRO PRO A . n 
A 1 886  VAL 886  886  886  VAL VAL A . n 
A 1 887  GLU 887  887  887  GLU GLU A . n 
A 1 888  PHE 888  888  888  PHE PHE A . n 
A 1 889  ALA 889  889  889  ALA ALA A . n 
A 1 890  THR 890  890  890  THR THR A . n 
A 1 891  ASP 891  891  891  ASP ASP A . n 
A 1 892  ARG 892  892  892  ARG ARG A . n 
A 1 893  VAL 893  893  893  VAL VAL A . n 
A 1 894  GLU 894  894  894  GLU GLU A . n 
A 1 895  GLU 895  895  895  GLU GLU A . n 
A 1 896  LEU 896  896  896  LEU LEU A . n 
A 1 897  PHE 897  897  897  PHE PHE A . n 
A 1 898  GLU 898  898  898  GLU GLU A . n 
A 1 899  TRP 899  899  899  TRP TRP A . n 
A 1 900  PHE 900  900  900  PHE PHE A . n 
A 1 901  GLN 901  901  901  GLN GLN A . n 
A 1 902  SER 902  902  902  SER SER A . n 
A 1 903  ILE 903  903  903  ILE ILE A . n 
A 1 904  ARG 904  904  904  ARG ARG A . n 
A 1 905  GLU 905  905  905  GLU GLU A . n 
A 1 906  ILE 906  906  906  ILE ILE A . n 
A 1 907  THR 907  907  907  THR THR A . n 
A 1 908  TRP 908  908  908  TRP TRP A . n 
A 1 909  LYS 909  909  ?    ?   ?   A . n 
A 1 910  ILE 910  910  ?    ?   ?   A . n 
A 1 911  ASP 911  911  ?    ?   ?   A . n 
A 1 912  THR 912  912  ?    ?   ?   A . n 
A 1 913  LYS 913  913  ?    ?   ?   A . n 
A 1 914  GLU 914  914  ?    ?   ?   A . n 
A 1 915  ASN 915  915  ?    ?   ?   A . n 
A 1 916  ASN 916  916  ?    ?   ?   A . n 
A 1 917  MET 917  917  ?    ?   ?   A . n 
A 1 918  LYS 918  918  ?    ?   ?   A . n 
A 1 919  TYR 919  919  ?    ?   ?   A . n 
A 1 920  TRP 920  920  ?    ?   ?   A . n 
A 1 921  GLU 921  921  ?    ?   ?   A . n 
A 1 922  LYS 922  922  ?    ?   ?   A . n 
A 1 923  ASN 923  923  ?    ?   ?   A . n 
A 1 924  GLN 924  924  924  GLN GLN A . n 
A 1 925  SER 925  925  925  SER SER A . n 
A 1 926  ILE 926  926  926  ILE ILE A . n 
A 1 927  ALA 927  927  927  ALA ALA A . n 
A 1 928  ILE 928  928  928  ILE ILE A . n 
A 1 929  GLU 929  929  929  GLU GLU A . n 
A 1 930  LEU 930  930  930  LEU LEU A . n 
A 1 931  SER 931  931  931  SER SER A . n 
A 1 932  ASP 932  932  932  ASP ASP A . n 
A 1 933  LEU 933  933  933  LEU LEU A . n 
A 1 934  VAL 934  934  934  VAL VAL A . n 
A 1 935  VAL 935  935  935  VAL VAL A . n 
A 1 936  TYR 936  936  936  TYR TYR A . n 
A 1 937  CYS 937  937  937  CYS CYS A . n 
A 1 938  LYS 938  938  938  LYS LYS A . n 
A 1 939  PRO 939  939  939  PRO PRO A . n 
A 1 940  THR 940  940  940  THR THR A . n 
A 1 941  SER 941  941  941  SER SER A . n 
A 1 942  LYS 942  942  942  LYS LYS A . n 
A 1 943  THR 943  943  943  THR THR A . n 
A 1 944  LYS 944  944  944  LYS LYS A . n 
A 1 945  ASP 945  945  945  ASP ASP A . n 
A 1 946  ASN 946  946  946  ASN ASN A . n 
A 1 947  LEU 947  947  947  LEU LEU A . n 
A 1 948  GLU 948  948  948  GLU GLU A . n 
A 1 949  ASN 949  949  949  ASN ASN A . n 
A 1 950  PRO 950  950  950  PRO PRO A . n 
A 1 951  ASP 951  951  951  ASP ASP A . n 
A 1 952  PHE 952  952  952  PHE PHE A . n 
A 1 953  ARG 953  953  953  ARG ARG A . n 
A 1 954  GLU 954  954  954  GLU GLU A . n 
A 1 955  ILE 955  955  955  ILE ILE A . n 
A 1 956  ARG 956  956  956  ARG ARG A . n 
A 1 957  SER 957  957  957  SER SER A . n 
A 1 958  PHE 958  958  958  PHE PHE A . n 
A 1 959  VAL 959  959  959  VAL VAL A . n 
A 1 960  GLU 960  960  960  GLU GLU A . n 
A 1 961  THR 961  961  961  THR THR A . n 
A 1 962  LYS 962  962  962  LYS LYS A . n 
A 1 963  ALA 963  963  963  ALA ALA A . n 
A 1 964  ASP 964  964  964  ASP ASP A . n 
A 1 965  SER 965  965  965  SER SER A . n 
A 1 966  ILE 966  966  966  ILE ILE A . n 
A 1 967  ILE 967  967  967  ILE ILE A . n 
A 1 968  ARG 968  968  968  ARG ARG A . n 
A 1 969  GLN 969  969  969  GLN GLN A . n 
A 1 970  LYS 970  970  970  LYS LYS A . n 
A 1 971  PRO 971  971  971  PRO PRO A . n 
A 1 972  VAL 972  972  972  VAL VAL A . n 
A 1 973  ASP 973  973  973  ASP ASP A . n 
A 1 974  LEU 974  974  974  LEU LEU A . n 
A 1 975  LEU 975  975  975  LEU LEU A . n 
A 1 976  LYS 976  976  976  LYS LYS A . n 
A 1 977  TYR 977  977  977  TYR TYR A . n 
A 1 978  ASN 978  978  978  ASN ASN A . n 
A 1 979  GLN 979  979  979  GLN GLN A . n 
A 1 980  LYS 980  980  980  LYS LYS A . n 
A 1 981  GLY 981  981  981  GLY GLY A . n 
A 1 982  LEU 982  982  982  LEU LEU A . n 
A 1 983  THR 983  983  983  THR THR A . n 
A 1 984  ARG 984  984  984  ARG ARG A . n 
A 1 985  VAL 985  985  985  VAL VAL A . n 
A 1 986  TYR 986  986  986  TYR TYR A . n 
A 1 987  PRO 987  987  987  PRO PRO A . n 
A 1 988  LYS 988  988  988  LYS LYS A . n 
A 1 989  GLY 989  989  989  GLY GLY A . n 
A 1 990  GLN 990  990  990  GLN GLN A . n 
A 1 991  ARG 991  991  991  ARG ARG A . n 
A 1 992  VAL 992  992  992  VAL VAL A . n 
A 1 993  ASP 993  993  993  ASP ASP A . n 
A 1 994  SER 994  994  994  SER SER A . n 
A 1 995  SER 995  995  995  SER SER A . n 
A 1 996  ASN 996  996  996  ASN ASN A . n 
A 1 997  TYR 997  997  997  TYR TYR A . n 
A 1 998  ASP 998  998  998  ASP ASP A . n 
A 1 999  PRO 999  999  999  PRO PRO A . n 
A 1 1000 PHE 1000 1000 1000 PHE PHE A . n 
A 1 1001 ARG 1001 1001 1001 ARG ARG A . n 
A 1 1002 LEU 1002 1002 1002 LEU LEU A . n 
A 1 1003 TRP 1003 1003 1003 TRP TRP A . n 
A 1 1004 LEU 1004 1004 1004 LEU LEU A . n 
A 1 1005 CYS 1005 1005 1005 CYS CYS A . n 
A 1 1006 GLY 1006 1006 1006 GLY GLY A . n 
A 1 1007 SER 1007 1007 1007 SER SER A . n 
A 1 1008 GLN 1008 1008 1008 GLN GLN A . n 
A 1 1009 MET 1009 1009 1009 MET MET A . n 
A 1 1010 VAL 1010 1010 1010 VAL VAL A . n 
A 1 1011 ALA 1011 1011 1011 ALA ALA A . n 
A 1 1012 LEU 1012 1012 1012 LEU LEU A . n 
A 1 1013 ASN 1013 1013 1013 ASN ASN A . n 
A 1 1014 PHE 1014 1014 1014 PHE PHE A . n 
A 1 1015 GLN 1015 1015 1015 GLN GLN A . n 
A 1 1016 THR 1016 1016 1016 THR THR A . n 
A 1 1017 ALA 1017 1017 1017 ALA ALA A . n 
A 1 1018 ASP 1018 1018 1018 ASP ASP A . n 
A 1 1019 LYS 1019 1019 1019 LYS LYS A . n 
A 1 1020 TYR 1020 1020 1020 TYR TYR A . n 
A 1 1021 MET 1021 1021 1021 MET MET A . n 
A 1 1022 GLN 1022 1022 1022 GLN GLN A . n 
A 1 1023 MET 1023 1023 1023 MET MET A . n 
A 1 1024 ASN 1024 1024 1024 ASN ASN A . n 
A 1 1025 HIS 1025 1025 1025 HIS HIS A . n 
A 1 1026 ALA 1026 1026 1026 ALA ALA A . n 
A 1 1027 LEU 1027 1027 1027 LEU LEU A . n 
A 1 1028 PHE 1028 1028 1028 PHE PHE A . n 
A 1 1029 SER 1029 1029 1029 SER SER A . n 
A 1 1030 LEU 1030 1030 1030 LEU LEU A . n 
A 1 1031 ASN 1031 1031 1031 ASN ASN A . n 
A 1 1032 GLY 1032 1032 1032 GLY GLY A . n 
A 1 1033 ARG 1033 1033 1033 ARG ARG A . n 
A 1 1034 THR 1034 1034 1034 THR THR A . n 
A 1 1035 GLY 1035 1035 1035 GLY GLY A . n 
A 1 1036 TYR 1036 1036 1036 TYR TYR A . n 
A 1 1037 VAL 1037 1037 1037 VAL VAL A . n 
A 1 1038 LEU 1038 1038 1038 LEU LEU A . n 
A 1 1039 GLN 1039 1039 1039 GLN GLN A . n 
A 1 1040 PRO 1040 1040 1040 PRO PRO A . n 
A 1 1041 GLU 1041 1041 1041 GLU GLU A . n 
A 1 1042 SER 1042 1042 1042 SER SER A . n 
A 1 1043 MET 1043 1043 1043 MET MET A . n 
A 1 1044 ARG 1044 1044 1044 ARG ARG A . n 
A 1 1045 THR 1045 1045 1045 THR THR A . n 
A 1 1046 GLU 1046 1046 1046 GLU GLU A . n 
A 1 1047 LYS 1047 1047 1047 LYS LYS A . n 
A 1 1048 TYR 1048 1048 1048 TYR TYR A . n 
A 1 1049 ASP 1049 1049 1049 ASP ASP A . n 
A 1 1050 PRO 1050 1050 1050 PRO PRO A . n 
A 1 1051 MET 1051 1051 1051 MET MET A . n 
A 1 1052 PRO 1052 1052 1052 PRO PRO A . n 
A 1 1053 PRO 1053 1053 1053 PRO PRO A . n 
A 1 1054 GLU 1054 1054 1054 GLU GLU A . n 
A 1 1055 SER 1055 1055 1055 SER SER A . n 
A 1 1056 GLN 1056 1056 1056 GLN GLN A . n 
A 1 1057 ARG 1057 1057 1057 ARG ARG A . n 
A 1 1058 LYS 1058 1058 1058 LYS LYS A . n 
A 1 1059 ILE 1059 1059 1059 ILE ILE A . n 
A 1 1060 LEU 1060 1060 1060 LEU LEU A . n 
A 1 1061 MET 1061 1061 1061 MET MET A . n 
A 1 1062 THR 1062 1062 1062 THR THR A . n 
A 1 1063 LEU 1063 1063 1063 LEU LEU A . n 
A 1 1064 THR 1064 1064 1064 THR THR A . n 
A 1 1065 VAL 1065 1065 1065 VAL VAL A . n 
A 1 1066 LYS 1066 1066 1066 LYS LYS A . n 
A 1 1067 VAL 1067 1067 1067 VAL VAL A . n 
A 1 1068 LEU 1068 1068 1068 LEU LEU A . n 
A 1 1069 GLY 1069 1069 1069 GLY GLY A . n 
A 1 1070 ALA 1070 1070 1070 ALA ALA A . n 
A 1 1071 ARG 1071 1071 1071 ARG ARG A . n 
A 1 1072 HIS 1072 1072 1072 HIS HIS A . n 
A 1 1073 LEU 1073 1073 1073 LEU LEU A . n 
A 1 1074 PRO 1074 1074 1074 PRO PRO A . n 
A 1 1075 LYS 1075 1075 1075 LYS LYS A . n 
A 1 1076 LEU 1076 1076 1076 LEU LEU A . n 
A 1 1077 GLY 1077 1077 1077 GLY GLY A . n 
A 1 1078 ARG 1078 1078 1078 ARG ARG A . n 
A 1 1079 SER 1079 1079 1079 SER SER A . n 
A 1 1080 ILE 1080 1080 1080 ILE ILE A . n 
A 1 1081 ALA 1081 1081 1081 ALA ALA A . n 
A 1 1082 CYS 1082 1082 1082 CYS CYS A . n 
A 1 1083 PRO 1083 1083 1083 PRO PRO A . n 
A 1 1084 PHE 1084 1084 1084 PHE PHE A . n 
A 1 1085 VAL 1085 1085 1085 VAL VAL A . n 
A 1 1086 GLU 1086 1086 1086 GLU GLU A . n 
A 1 1087 VAL 1087 1087 1087 VAL VAL A . n 
A 1 1088 GLU 1088 1088 1088 GLU GLU A . n 
A 1 1089 ILE 1089 1089 1089 ILE ILE A . n 
A 1 1090 CYS 1090 1090 1090 CYS CYS A . n 
A 1 1091 GLY 1091 1091 1091 GLY GLY A . n 
A 1 1092 ALA 1092 1092 1092 ALA ALA A . n 
A 1 1093 GLU 1093 1093 1093 GLU GLU A . n 
A 1 1094 TYR 1094 1094 1094 TYR TYR A . n 
A 1 1095 ASP 1095 1095 1095 ASP ASP A . n 
A 1 1096 ASN 1096 1096 1096 ASN ASN A . n 
A 1 1097 ASN 1097 1097 1097 ASN ASN A . n 
A 1 1098 LYS 1098 1098 1098 LYS LYS A . n 
A 1 1099 PHE 1099 1099 1099 PHE PHE A . n 
A 1 1100 LYS 1100 1100 1100 LYS LYS A . n 
A 1 1101 THR 1101 1101 1101 THR THR A . n 
A 1 1102 THR 1102 1102 1102 THR THR A . n 
A 1 1103 VAL 1103 1103 1103 VAL VAL A . n 
A 1 1104 VAL 1104 1104 1104 VAL VAL A . n 
A 1 1105 ASN 1105 1105 1105 ASN ASN A . n 
A 1 1106 ASP 1106 1106 1106 ASP ASP A . n 
A 1 1107 ASN 1107 1107 1107 ASN ASN A . n 
A 1 1108 GLY 1108 1108 1108 GLY GLY A . n 
A 1 1109 LEU 1109 1109 1109 LEU LEU A . n 
A 1 1110 SER 1110 1110 1110 SER SER A . n 
A 1 1111 PRO 1111 1111 1111 PRO PRO A . n 
A 1 1112 ILE 1112 1112 1112 ILE ILE A . n 
A 1 1113 TRP 1113 1113 1113 TRP TRP A . n 
A 1 1114 ALA 1114 1114 1114 ALA ALA A . n 
A 1 1115 PRO 1115 1115 1115 PRO PRO A . n 
A 1 1116 THR 1116 1116 1116 THR THR A . n 
A 1 1117 GLN 1117 1117 1117 GLN GLN A . n 
A 1 1118 GLU 1118 1118 1118 GLU GLU A . n 
A 1 1119 LYS 1119 1119 1119 LYS LYS A . n 
A 1 1120 VAL 1120 1120 1120 VAL VAL A . n 
A 1 1121 THR 1121 1121 1121 THR THR A . n 
A 1 1122 PHE 1122 1122 1122 PHE PHE A . n 
A 1 1123 GLU 1123 1123 1123 GLU GLU A . n 
A 1 1124 ILE 1124 1124 1124 ILE ILE A . n 
A 1 1125 TYR 1125 1125 1125 TYR TYR A . n 
A 1 1126 ASP 1126 1126 1126 ASP ASP A . n 
A 1 1127 PRO 1127 1127 1127 PRO PRO A . n 
A 1 1128 ASN 1128 1128 1128 ASN ASN A . n 
A 1 1129 LEU 1129 1129 1129 LEU LEU A . n 
A 1 1130 ALA 1130 1130 1130 ALA ALA A . n 
A 1 1131 PHE 1131 1131 1131 PHE PHE A . n 
A 1 1132 LEU 1132 1132 1132 LEU LEU A . n 
A 1 1133 ARG 1133 1133 1133 ARG ARG A . n 
A 1 1134 PHE 1134 1134 1134 PHE PHE A . n 
A 1 1135 VAL 1135 1135 1135 VAL VAL A . n 
A 1 1136 VAL 1136 1136 1136 VAL VAL A . n 
A 1 1137 TYR 1137 1137 1137 TYR TYR A . n 
A 1 1138 GLU 1138 1138 1138 GLU GLU A . n 
A 1 1139 GLU 1139 1139 1139 GLU GLU A . n 
A 1 1140 ASP 1140 1140 1140 ASP ASP A . n 
A 1 1141 MET 1141 1141 1141 MET MET A . n 
A 1 1142 PHE 1142 1142 1142 PHE PHE A . n 
A 1 1143 SER 1143 1143 1143 SER SER A . n 
A 1 1144 ASP 1144 1144 1144 ASP ASP A . n 
A 1 1145 PRO 1145 1145 1145 PRO PRO A . n 
A 1 1146 ASN 1146 1146 1146 ASN ASN A . n 
A 1 1147 PHE 1147 1147 1147 PHE PHE A . n 
A 1 1148 LEU 1148 1148 1148 LEU LEU A . n 
A 1 1149 ALA 1149 1149 1149 ALA ALA A . n 
A 1 1150 HIS 1150 1150 1150 HIS HIS A . n 
A 1 1151 ALA 1151 1151 1151 ALA ALA A . n 
A 1 1152 THR 1152 1152 1152 THR THR A . n 
A 1 1153 TYR 1153 1153 1153 TYR TYR A . n 
A 1 1154 PRO 1154 1154 1154 PRO PRO A . n 
A 1 1155 ILE 1155 1155 1155 ILE ILE A . n 
A 1 1156 LYS 1156 1156 1156 LYS LYS A . n 
A 1 1157 ALA 1157 1157 1157 ALA ALA A . n 
A 1 1158 VAL 1158 1158 1158 VAL VAL A . n 
A 1 1159 LYS 1159 1159 1159 LYS LYS A . n 
A 1 1160 SER 1160 1160 1160 SER SER A . n 
A 1 1161 GLY 1161 1161 1161 GLY GLY A . n 
A 1 1162 PHE 1162 1162 1162 PHE PHE A . n 
A 1 1163 ARG 1163 1163 1163 ARG ARG A . n 
A 1 1164 SER 1164 1164 1164 SER SER A . n 
A 1 1165 VAL 1165 1165 1165 VAL VAL A . n 
A 1 1166 PRO 1166 1166 1166 PRO PRO A . n 
A 1 1167 LEU 1167 1167 1167 LEU LEU A . n 
A 1 1168 LYS 1168 1168 1168 LYS LYS A . n 
A 1 1169 ASN 1169 1169 1169 ASN ASN A . n 
A 1 1170 GLY 1170 1170 1170 GLY GLY A . n 
A 1 1171 TYR 1171 1171 1171 TYR TYR A . n 
A 1 1172 SER 1172 1172 1172 SER SER A . n 
A 1 1173 GLU 1173 1173 1173 GLU GLU A . n 
A 1 1174 ASP 1174 1174 1174 ASP ASP A . n 
A 1 1175 ILE 1175 1175 1175 ILE ILE A . n 
A 1 1176 GLU 1176 1176 1176 GLU GLU A . n 
A 1 1177 LEU 1177 1177 1177 LEU LEU A . n 
A 1 1178 ALA 1178 1178 1178 ALA ALA A . n 
A 1 1179 SER 1179 1179 1179 SER SER A . n 
A 1 1180 LEU 1180 1180 1180 LEU LEU A . n 
A 1 1181 LEU 1181 1181 1181 LEU LEU A . n 
A 1 1182 VAL 1182 1182 1182 VAL VAL A . n 
A 1 1183 PHE 1183 1183 1183 PHE PHE A . n 
A 1 1184 CYS 1184 1184 1184 CYS CYS A . n 
A 1 1185 GLU 1185 1185 1185 GLU GLU A . n 
A 1 1186 MET 1186 1186 1186 MET MET A . n 
A 1 1187 ARG 1187 1187 1187 ARG ARG A . n 
A 1 1188 PRO 1188 1188 1188 PRO PRO A . n 
A 1 1189 VAL 1189 1189 1189 VAL VAL A . n 
A 1 1190 LEU 1190 1190 1190 LEU LEU A . n 
A 1 1191 GLU 1191 1191 ?    ?   ?   A . n 
A 1 1192 SER 1192 1192 ?    ?   ?   A . n 
A 1 1193 GLU 1193 1193 ?    ?   ?   A . n 
A 1 1194 GLU 1194 1194 ?    ?   ?   A . n 
A 1 1195 GLU 1195 1195 ?    ?   ?   A . n 
A 1 1196 LEU 1196 1196 ?    ?   ?   A . n 
A 1 1197 TYR 1197 1197 ?    ?   ?   A . n 
A 1 1198 SER 1198 1198 ?    ?   ?   A . n 
A 1 1199 SER 1199 1199 ?    ?   ?   A . n 
A 1 1200 CYS 1200 1200 ?    ?   ?   A . n 
A 1 1201 ARG 1201 1201 ?    ?   ?   A . n 
A 1 1202 GLN 1202 1202 ?    ?   ?   A . n 
A 1 1203 LEU 1203 1203 ?    ?   ?   A . n 
A 1 1204 ARG 1204 1204 ?    ?   ?   A . n 
A 1 1205 ARG 1205 1205 ?    ?   ?   A . n 
A 1 1206 ARG 1206 1206 ?    ?   ?   A . n 
A 1 1207 GLN 1207 1207 ?    ?   ?   A . n 
A 1 1208 GLU 1208 1208 ?    ?   ?   A . n 
A 1 1209 GLU 1209 1209 ?    ?   ?   A . n 
A 1 1210 LEU 1210 1210 ?    ?   ?   A . n 
A 1 1211 ASN 1211 1211 ?    ?   ?   A . n 
A 1 1212 ASN 1212 1212 ?    ?   ?   A . n 
A 1 1213 GLN 1213 1213 ?    ?   ?   A . n 
A 1 1214 LEU 1214 1214 ?    ?   ?   A . n 
A 1 1215 PHE 1215 1215 ?    ?   ?   A . n 
A 1 1216 LEU 1216 1216 ?    ?   ?   A . n 
A 1 1217 TYR 1217 1217 ?    ?   ?   A . n 
A 1 1218 ASP 1218 1218 ?    ?   ?   A . n 
A 1 1219 THR 1219 1219 ?    ?   ?   A . n 
A 1 1220 HIS 1220 1220 ?    ?   ?   A . n 
A 1 1221 GLN 1221 1221 ?    ?   ?   A . n 
A 1 1222 ASN 1222 1222 ?    ?   ?   A . n 
A 1 1223 LEU 1223 1223 ?    ?   ?   A . n 
A 1 1224 ARG 1224 1224 ?    ?   ?   A . n 
A 1 1225 ASN 1225 1225 ?    ?   ?   A . n 
A 1 1226 ALA 1226 1226 ?    ?   ?   A . n 
A 1 1227 ASN 1227 1227 ?    ?   ?   A . n 
A 1 1228 ARG 1228 1228 ?    ?   ?   A . n 
A 1 1229 ASP 1229 1229 ?    ?   ?   A . n 
A 1 1230 ALA 1230 1230 ?    ?   ?   A . n 
A 1 1231 LEU 1231 1231 ?    ?   ?   A . n 
A 1 1232 VAL 1232 1232 ?    ?   ?   A . n 
A 1 1233 LYS 1233 1233 ?    ?   ?   A . n 
A 1 1234 GLU 1234 1234 ?    ?   ?   A . n 
A 1 1235 PHE 1235 1235 ?    ?   ?   A . n 
A 1 1236 SER 1236 1236 ?    ?   ?   A . n 
A 1 1237 VAL 1237 1237 ?    ?   ?   A . n 
A 1 1238 ASN 1238 1238 ?    ?   ?   A . n 
A 1 1239 GLU 1239 1239 ?    ?   ?   A . n 
A 1 1240 ASN 1240 1240 ?    ?   ?   A . n 
A 1 1241 GLN 1241 1241 ?    ?   ?   A . n 
A 1 1242 LEU 1242 1242 ?    ?   ?   A . n 
A 1 1243 GLN 1243 1243 ?    ?   ?   A . n 
A 1 1244 LEU 1244 1244 ?    ?   ?   A . n 
A 1 1245 TYR 1245 1245 ?    ?   ?   A . n 
A 1 1246 GLN 1246 1246 ?    ?   ?   A . n 
A 1 1247 GLU 1247 1247 ?    ?   ?   A . n 
A 1 1248 LYS 1248 1248 ?    ?   ?   A . n 
A 1 1249 CYS 1249 1249 ?    ?   ?   A . n 
A 1 1250 ASN 1250 1250 ?    ?   ?   A . n 
A 1 1251 LYS 1251 1251 ?    ?   ?   A . n 
A 1 1252 ARG 1252 1252 ?    ?   ?   A . n 
A 1 1253 LEU 1253 1253 ?    ?   ?   A . n 
A 1 1254 ARG 1254 1254 ?    ?   ?   A . n 
A 1 1255 GLU 1255 1255 ?    ?   ?   A . n 
A 1 1256 LYS 1256 1256 ?    ?   ?   A . n 
A 1 1257 ARG 1257 1257 ?    ?   ?   A . n 
A 1 1258 VAL 1258 1258 ?    ?   ?   A . n 
A 1 1259 SER 1259 1259 ?    ?   ?   A . n 
A 1 1260 ASN 1260 1260 ?    ?   ?   A . n 
A 1 1261 SER 1261 1261 ?    ?   ?   A . n 
A 1 1262 LYS 1262 1262 ?    ?   ?   A . n 
A 1 1263 PHE 1263 1263 ?    ?   ?   A . n 
A 1 1264 TYR 1264 1264 ?    ?   ?   A . n 
A 1 1265 SER 1265 1265 ?    ?   ?   A . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8QJU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8QJU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8QJU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               244.720 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.859 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8QJU 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.5 
_refine.ls_d_res_low                             3.5 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     107886 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.39488 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.39488 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.435 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             17.532 
_refine.overall_SU_ML                            0.297 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               9441 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.008  0.012  9665  ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  9057  ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 1.216  1.654  13055 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.421  1.575  20916 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 4.972  5.000  1148  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 3.407  5.000  72    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 25.303 10.000 1751  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.057  0.200  1399  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.006  0.020  11232 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.002  0.020  2296  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 19.659 23.165 4604  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 19.657 23.165 4604  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 31.930 41.728 5748  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 31.927 41.728 5749  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 22.067 25.933 5061  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 22.065 25.934 5062  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 36.803 46.536 7308  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 65.999 268.40 41319 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 65.999 268.40 41320 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.000 
_refine_ls_shell.d_res_low                        3.078 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             7997 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.621 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8QJU 
_struct.title                        
'Structure of the human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) protein' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8QJU 
_struct_keywords.text            'Lipid metabolism, LIPID BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'LIPID BINDING PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PLCG2_HUMAN 
_struct_ref.pdbx_db_accession          P16885 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSK
DFERAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNS
ISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSH
YWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFP
VILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGT
FLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNP
HESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVS
KEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQ
QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQP
ESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKV
TFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLREKRVSNSKFYS
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8QJU 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1265 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P16885 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1265 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       1265 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 11   ? GLY A 25   ? ALA A 11   GLY A 25   1 ? 15 
HELX_P HELX_P2  AA2 SER A 79   ? GLU A 83   ? SER A 79   GLU A 83   5 ? 5  
HELX_P HELX_P3  AA3 SER A 115  ? ALA A 136  ? SER A 115  ALA A 136  1 ? 22 
HELX_P HELX_P4  AA4 SER A 137  ? ASP A 154  ? SER A 137  ASP A 154  1 ? 18 
HELX_P HELX_P5  AA5 LEU A 163  ? ILE A 173  ? LEU A 163  ILE A 173  1 ? 11 
HELX_P HELX_P6  AA6 SER A 179  ? GLY A 191  ? SER A 179  GLY A 191  1 ? 13 
HELX_P HELX_P7  AA7 PHE A 199  ? LYS A 222  ? PHE A 199  LYS A 222  1 ? 24 
HELX_P HELX_P8  AA8 LEU A 243  ? HIS A 252  ? LEU A 243  HIS A 252  1 ? 10 
HELX_P HELX_P9  AA9 GLU A 256  ? GLN A 260  ? GLU A 256  GLN A 260  5 ? 5  
HELX_P HELX_P10 AB1 ASP A 261  ? ASP A 274  ? ASP A 261  ASP A 274  1 ? 14 
HELX_P HELX_P11 AB2 PHE A 286  ? PHE A 295  ? PHE A 286  PHE A 295  1 ? 10 
HELX_P HELX_P12 AB3 SER A 296  ? SER A 300  ? SER A 296  SER A 300  5 ? 5  
HELX_P HELX_P13 AB4 GLU A 304  ? ALA A 308  ? GLU A 304  ALA A 308  5 ? 5  
HELX_P HELX_P14 AB5 MET A 311  ? ASN A 315  ? MET A 311  ASN A 315  5 ? 5  
HELX_P HELX_P15 AB6 PRO A 317  ? TYR A 321  ? PRO A 317  TYR A 321  5 ? 5  
HELX_P HELX_P16 AB7 SER A 341  ? GLY A 352  ? SER A 341  GLY A 352  1 ? 12 
HELX_P HELX_P17 AB8 PHE A 382  ? PHE A 394  ? PHE A 382  PHE A 394  1 ? 13 
HELX_P HELX_P18 AB9 SER A 410  ? GLY A 426  ? SER A 410  GLY A 426  1 ? 17 
HELX_P HELX_P19 AC1 ASP A 427  ? LEU A 429  ? ASP A 427  LEU A 429  5 ? 3  
HELX_P HELX_P20 AC2 LEU A 526  ? GLU A 530  ? LEU A 526  GLU A 530  5 ? 5  
HELX_P HELX_P21 AC3 LYS A 539  ? GLY A 555  ? LYS A 539  GLY A 555  1 ? 17 
HELX_P HELX_P22 AC4 SER A 609  ? THR A 620  ? SER A 609  THR A 620  1 ? 12 
HELX_P HELX_P23 AC5 ASN A 639  ? LYS A 644  ? ASN A 639  LYS A 644  1 ? 6  
HELX_P HELX_P24 AC6 SER A 652  ? ILE A 663  ? SER A 652  ILE A 663  1 ? 12 
HELX_P HELX_P25 AC7 SER A 712  ? HIS A 723  ? SER A 712  HIS A 723  1 ? 12 
HELX_P HELX_P26 AC8 THR A 736  ? TYR A 743  ? THR A 736  TYR A 743  1 ? 8  
HELX_P HELX_P27 AC9 LEU A 835  ? ASN A 843  ? LEU A 835  ASN A 843  1 ? 9  
HELX_P HELX_P28 AD1 LEU A 845  ? CYS A 849  ? LEU A 845  CYS A 849  5 ? 5  
HELX_P HELX_P29 AD2 ARG A 892  ? TRP A 908  ? ARG A 892  TRP A 908  1 ? 17 
HELX_P HELX_P30 AD3 ALA A 927  ? VAL A 934  ? ALA A 927  VAL A 934  1 ? 8  
HELX_P HELX_P31 AD4 VAL A 959  ? LYS A 970  ? VAL A 959  LYS A 970  1 ? 12 
HELX_P HELX_P32 AD5 LYS A 970  ? GLN A 979  ? LYS A 970  GLN A 979  1 ? 10 
HELX_P HELX_P33 AD6 PRO A 999  ? CYS A 1005 ? PRO A 999  CYS A 1005 1 ? 7  
HELX_P HELX_P34 AD7 ASP A 1018 ? LEU A 1030 ? ASP A 1018 LEU A 1030 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            348 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            353 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             348 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             353 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.069 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       348 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      353 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        348 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       353 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 5 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 5 ? 
AB1 ? 3 ? 
AB2 ? 2 ? 
AB3 ? 4 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
AB6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? parallel      
AB2 1 2 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? parallel      
AB3 3 4 ? parallel      
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 63   ? ASP A 66   ? GLY A 63   ASP A 66   
AA1 2 GLN A 51   ? SER A 55   ? GLN A 51   SER A 55   
AA1 3 GLU A 39   ? ILE A 46   ? GLU A 39   ILE A 46   
AA1 4 THR A 26   ? PHE A 31   ? THR A 26   PHE A 31   
AA1 5 SER A 107  ? ALA A 113  ? SER A 107  ALA A 113  
AA1 6 CYS A 95   ? TYR A 100  ? CYS A 95   TYR A 100  
AA1 7 ILE A 70   ? GLU A 72   ? ILE A 70   GLU A 72   
AA2 1 SER A 160  ? SER A 162  ? SER A 160  SER A 162  
AA2 2 GLU A 196  ? SER A 198  ? GLU A 196  SER A 198  
AA3 1 VAL A 241  ? TYR A 242  ? VAL A 241  TYR A 242  
AA3 2 PHE A 284  ? LEU A 285  ? PHE A 284  LEU A 285  
AA4 1 LEU A 331  ? THR A 332  ? LEU A 331  THR A 332  
AA4 2 GLU A 339  ? SER A 340  ? GLU A 339  SER A 340  
AA5 1 VAL A 369  ? ILE A 370  ? VAL A 369  ILE A 370  
AA5 2 ILE A 380  ? LYS A 381  ? ILE A 380  LYS A 381  
AA6 1 GLY A 851  ? ASP A 854  ? GLY A 851  ASP A 854  
AA6 2 LYS A 502  ? PHE A 505  ? LYS A 502  PHE A 505  
AA6 3 THR A 492  ? ALA A 499  ? THR A 492  ALA A 499  
AA6 4 GLY A 479  ? MET A 483  ? GLY A 479  MET A 483  
AA6 5 PHE A 888  ? ALA A 889  ? PHE A 888  ALA A 889  
AA7 1 PHE A 561  ? GLU A 565  ? PHE A 561  GLU A 565  
AA7 2 TYR A 573  ? ARG A 579  ? TYR A 573  ARG A 579  
AA7 3 ARG A 582  ? GLU A 593  ? ARG A 582  GLU A 593  
AA7 4 THR A 596  ? TYR A 600  ? THR A 596  TYR A 600  
AA8 1 LEU A 622  ? CYS A 624  ? LEU A 622  CYS A 624  
AA8 2 PHE A 627  ? LEU A 629  ? PHE A 627  LEU A 629  
AA9 1 TYR A 647  ? TYR A 648  ? TYR A 647  TYR A 648  
AA9 2 ALA A 668  ? LYS A 673  ? ALA A 668  LYS A 673  
AA9 3 TYR A 680  ? ARG A 685  ? TYR A 680  ARG A 685  
AA9 4 VAL A 690  ? ARG A 697  ? VAL A 690  ARG A 697  
AA9 5 PHE A 702  ? LEU A 704  ? PHE A 702  LEU A 704  
AB1 1 TYR A 647  ? TYR A 648  ? TYR A 647  TYR A 648  
AB1 2 ALA A 668  ? LYS A 673  ? ALA A 668  LYS A 673  
AB1 3 TYR A 733  ? PRO A 734  ? TYR A 733  PRO A 734  
AB2 1 TYR A 858  ? LYS A 862  ? TYR A 858  LYS A 862  
AB2 2 PHE A 874  ? PRO A 878  ? PHE A 874  PRO A 878  
AB3 1 LYS A 938  ? PRO A 939  ? LYS A 938  PRO A 939  
AB3 2 GLU A 954  ? ARG A 956  ? GLU A 954  ARG A 956  
AB3 3 LEU A 982  ? VAL A 985  ? LEU A 982  VAL A 985  
AB3 4 MET A 1009 ? VAL A 1010 ? MET A 1009 VAL A 1010 
AB4 1 MET A 1061 ? LEU A 1063 ? MET A 1061 LEU A 1063 
AB4 2 MET A 1186 ? PRO A 1188 ? MET A 1186 PRO A 1188 
AB5 1 LYS A 1098 ? LYS A 1100 ? LYS A 1098 LYS A 1100 
AB5 2 CYS A 1082 ? GLU A 1088 ? CYS A 1082 GLU A 1088 
AB5 3 LEU A 1132 ? ASP A 1140 ? LEU A 1132 ASP A 1140 
AB5 4 ASP A 1144 ? TYR A 1153 ? ASP A 1144 TYR A 1153 
AB6 1 ARG A 1163 ? SER A 1164 ? ARG A 1163 SER A 1164 
AB6 2 LEU A 1181 ? VAL A 1182 ? LEU A 1181 VAL A 1182 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 65   ? O LEU A 65   N VAL A 52   ? N VAL A 52   
AA1 2 3 O GLN A 51   ? O GLN A 51   N ILE A 46   ? N ILE A 46   
AA1 3 4 O GLU A 39   ? O GLU A 39   N VAL A 30   ? N VAL A 30   
AA1 4 5 N THR A 29   ? N THR A 29   O ALA A 112  ? O ALA A 112  
AA1 5 6 O LEU A 109  ? O LEU A 109  N ILE A 98   ? N ILE A 98   
AA1 6 7 O LEU A 99   ? O LEU A 99   N GLU A 72   ? N GLU A 72   
AA2 1 2 N ILE A 161  ? N ILE A 161  O LEU A 197  ? O LEU A 197  
AA3 1 2 N VAL A 241  ? N VAL A 241  O LEU A 285  ? O LEU A 285  
AA4 1 2 N THR A 332  ? N THR A 332  O GLU A 339  ? O GLU A 339  
AA5 1 2 N ILE A 370  ? N ILE A 370  O ILE A 380  ? O ILE A 380  
AA6 1 2 O GLY A 851  ? O GLY A 851  N PHE A 505  ? N PHE A 505  
AA6 2 3 O SER A 504  ? O SER A 504  N ALA A 497  ? N ALA A 497  
AA6 3 4 O CYS A 496  ? O CYS A 496  N GLY A 479  ? N GLY A 479  
AA6 4 5 N TYR A 482  ? N TYR A 482  O ALA A 889  ? O ALA A 889  
AA7 1 2 N ARG A 564  ? N ARG A 564  O THR A 574  ? O THR A 574  
AA7 2 3 N LEU A 575  ? N LEU A 575  O CYS A 586  ? O CYS A 586  
AA7 3 4 N THR A 591  ? N THR A 591  O LYS A 598  ? O LYS A 598  
AA8 1 2 N LEU A 622  ? N LEU A 622  O LEU A 629  ? O LEU A 629  
AA9 1 2 N TYR A 648  ? N TYR A 648  O ILE A 671  ? O ILE A 671  
AA9 2 3 N LEU A 670  ? N LEU A 670  O THR A 683  ? O THR A 683  
AA9 3 4 N ILE A 682  ? N ILE A 682  O CYS A 693  ? O CYS A 693  
AA9 4 5 N ASN A 696  ? N ASN A 696  O VAL A 703  ? O VAL A 703  
AB1 1 2 N TYR A 648  ? N TYR A 648  O ILE A 671  ? O ILE A 671  
AB1 2 3 N PHE A 669  ? N PHE A 669  O TYR A 733  ? O TYR A 733  
AB2 1 2 N VAL A 861  ? N VAL A 861  O ILE A 875  ? O ILE A 875  
AB3 1 2 N LYS A 938  ? N LYS A 938  O ILE A 955  ? O ILE A 955  
AB3 2 3 N ARG A 956  ? N ARG A 956  O ARG A 984  ? O ARG A 984  
AB3 3 4 N THR A 983  ? N THR A 983  O MET A 1009 ? O MET A 1009 
AB4 1 2 N THR A 1062 ? N THR A 1062 O ARG A 1187 ? O ARG A 1187 
AB5 1 2 O PHE A 1099 ? O PHE A 1099 N VAL A 1087 ? N VAL A 1087 
AB5 2 3 N GLU A 1086 ? N GLU A 1086 O VAL A 1135 ? O VAL A 1135 
AB5 3 4 N PHE A 1134 ? N PHE A 1134 O ALA A 1151 ? O ALA A 1151 
AB6 1 2 N ARG A 1163 ? N ARG A 1163 O VAL A 1182 ? O VAL A 1182 
# 
_pdbx_entry_details.entry_id                   8QJU 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 35   ? ? 81.26   8.02    
2  1 SER A 36   ? ? 52.17   -124.11 
3  1 THR A 57   ? ? -126.54 -121.73 
4  1 ASP A 59   ? ? 86.28   0.32    
5  1 MET A 68   ? ? -37.04  -33.20  
6  1 LYS A 80   ? ? 50.85   -130.40 
7  1 ASP A 81   ? ? 19.31   -83.57  
8  1 ALA A 85   ? ? 56.96   -137.29 
9  1 ASN A 174  ? ? 80.30   43.13   
10 1 LYS A 222  ? ? -60.02  60.29   
11 1 SER A 225  ? ? 80.56   5.95    
12 1 VAL A 227  ? ? 77.83   -3.36   
13 1 ILE A 229  ? ? 36.72   64.34   
14 1 ASP A 237  ? ? 80.45   4.40    
15 1 SER A 239  ? ? 61.53   -179.99 
16 1 HIS A 252  ? ? -105.95 -66.50  
17 1 GLU A 253  ? ? -54.28  -71.64  
18 1 GLU A 256  ? ? -163.60 86.75   
19 1 HIS A 257  ? ? -61.26  2.82    
20 1 THR A 276  ? ? 53.94   -123.33 
21 1 ARG A 278  ? ? 89.29   -4.22   
22 1 THR A 280  ? ? 82.95   -68.30  
23 1 HIS A 327  ? ? -66.28  -121.15 
24 1 CYS A 355  ? ? 172.26  49.16   
25 1 TRP A 374  ? ? 78.51   -20.24  
26 1 ALA A 436  ? ? 53.75   -126.69 
27 1 ALA A 438  ? ? 57.87   107.81  
28 1 LYS A 476  ? ? 90.25   0.23    
29 1 ILE A 487  ? ? -90.64  -108.42 
30 1 LYS A 535  ? ? 39.78   -130.44 
31 1 ASN A 571  ? ? 78.96   -6.54   
32 1 THR A 632  ? ? -109.44 -100.78 
33 1 PRO A 636  ? ? -100.14 58.41   
34 1 PRO A 638  ? ? -71.11  -100.01 
35 1 GLU A 642  ? ? -168.01 -42.60  
36 1 TRP A 646  ? ? -75.44  46.96   
37 1 SER A 650  ? ? 81.81   1.47    
38 1 HIS A 723  ? ? -106.38 -151.06 
39 1 ARG A 727  ? ? 46.65   -123.72 
40 1 ARG A 732  ? ? -131.94 -30.58  
41 1 GLN A 865  ? ? 79.11   178.39  
42 1 GLN A 869  ? ? 65.92   -142.01 
43 1 SER A 925  ? ? -77.24  -164.57 
44 1 ILE A 926  ? ? 86.75   101.94  
45 1 CYS A 937  ? ? 59.95   102.46  
46 1 LYS A 944  ? ? -43.86  -13.30  
47 1 GLU A 948  ? ? 126.71  -177.46 
48 1 ASN A 949  ? ? 32.15   52.85   
49 1 LYS A 980  ? ? 81.40   12.64   
50 1 SER A 994  ? ? 89.88   5.27    
51 1 ASP A 998  ? ? -59.93  102.85  
52 1 THR A 1045 ? ? 170.06  -150.20 
53 1 LYS A 1058 ? ? 80.43   177.05  
54 1 ARG A 1071 ? ? -174.14 125.94  
55 1 ILE A 1089 ? ? -119.09 71.38   
56 1 ASN A 1105 ? ? -63.21  -172.81 
57 1 ASN A 1107 ? ? 162.82  88.37   
58 1 ALA A 1114 ? ? -30.96  123.28  
59 1 PRO A 1115 ? ? -10.01  71.73   
60 1 GLN A 1117 ? ? 62.71   -73.13  
61 1 GLU A 1118 ? ? 40.89   -115.45 
62 1 MET A 1141 ? ? 51.37   -137.02 
63 1 PHE A 1142 ? ? -32.59  121.24  
64 1 GLU A 1176 ? ? -59.74  177.71  
65 1 LEU A 1177 ? ? -34.34  83.99   
66 1 SER A 1179 ? ? 171.52  159.66  
67 1 MET A 1186 ? ? -108.09 56.29   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8QJU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8QJU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               130911 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 CELL 
_em_entity_assembly.name                 '1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8QJU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'UltrAuFoil R0./1' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8QJU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8QJU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1    
2   1 Y 1 A SER 2    ? A SER 2    
3   1 Y 1 A THR 3    ? A THR 3    
4   1 Y 1 A THR 4    ? A THR 4    
5   1 Y 1 A VAL 5    ? A VAL 5    
6   1 Y 1 A ASN 6    ? A ASN 6    
7   1 Y 1 A VAL 7    ? A VAL 7    
8   1 Y 1 A ASP 8    ? A ASP 8    
9   1 Y 1 A SER 9    ? A SER 9    
10  1 Y 1 A LEU 10   ? A LEU 10   
11  1 Y 1 A PRO 460  ? A PRO 460  
12  1 Y 1 A ARG 461  ? A ARG 461  
13  1 Y 1 A GLY 462  ? A GLY 462  
14  1 Y 1 A ASP 463  ? A ASP 463  
15  1 Y 1 A VAL 464  ? A VAL 464  
16  1 Y 1 A ASP 465  ? A ASP 465  
17  1 Y 1 A VAL 466  ? A VAL 466  
18  1 Y 1 A ASN 467  ? A ASN 467  
19  1 Y 1 A MET 468  ? A MET 468  
20  1 Y 1 A GLU 469  ? A GLU 469  
21  1 Y 1 A ASP 470  ? A ASP 470  
22  1 Y 1 A LYS 471  ? A LYS 471  
23  1 Y 1 A LYS 472  ? A LYS 472  
24  1 Y 1 A ASP 473  ? A ASP 473  
25  1 Y 1 A GLU 474  ? A GLU 474  
26  1 Y 1 A GLN 511  ? A GLN 511  
27  1 Y 1 A THR 512  ? A THR 512  
28  1 Y 1 A MET 513  ? A MET 513  
29  1 Y 1 A GLU 514  ? A GLU 514  
30  1 Y 1 A GLU 515  ? A GLU 515  
31  1 Y 1 A GLU 516  ? A GLU 516  
32  1 Y 1 A VAL 517  ? A VAL 517  
33  1 Y 1 A PRO 518  ? A PRO 518  
34  1 Y 1 A GLN 519  ? A GLN 519  
35  1 Y 1 A ASP 520  ? A ASP 520  
36  1 Y 1 A ILE 521  ? A ILE 521  
37  1 Y 1 A PRO 522  ? A PRO 522  
38  1 Y 1 A PRO 523  ? A PRO 523  
39  1 Y 1 A THR 524  ? A THR 524  
40  1 Y 1 A GLU 525  ? A GLU 525  
41  1 Y 1 A ASN 744  ? A ASN 744  
42  1 Y 1 A MET 745  ? A MET 745  
43  1 Y 1 A GLU 746  ? A GLU 746  
44  1 Y 1 A ARG 747  ? A ARG 747  
45  1 Y 1 A ASP 748  ? A ASP 748  
46  1 Y 1 A ILE 749  ? A ILE 749  
47  1 Y 1 A ASN 750  ? A ASN 750  
48  1 Y 1 A SER 751  ? A SER 751  
49  1 Y 1 A LEU 752  ? A LEU 752  
50  1 Y 1 A TYR 753  ? A TYR 753  
51  1 Y 1 A ASP 754  ? A ASP 754  
52  1 Y 1 A VAL 755  ? A VAL 755  
53  1 Y 1 A SER 756  ? A SER 756  
54  1 Y 1 A ARG 757  ? A ARG 757  
55  1 Y 1 A MET 758  ? A MET 758  
56  1 Y 1 A TYR 759  ? A TYR 759  
57  1 Y 1 A VAL 760  ? A VAL 760  
58  1 Y 1 A ASP 761  ? A ASP 761  
59  1 Y 1 A PRO 762  ? A PRO 762  
60  1 Y 1 A SER 763  ? A SER 763  
61  1 Y 1 A GLU 764  ? A GLU 764  
62  1 Y 1 A ILE 765  ? A ILE 765  
63  1 Y 1 A ASN 766  ? A ASN 766  
64  1 Y 1 A PRO 767  ? A PRO 767  
65  1 Y 1 A SER 768  ? A SER 768  
66  1 Y 1 A MET 769  ? A MET 769  
67  1 Y 1 A PRO 770  ? A PRO 770  
68  1 Y 1 A GLN 771  ? A GLN 771  
69  1 Y 1 A ARG 772  ? A ARG 772  
70  1 Y 1 A THR 773  ? A THR 773  
71  1 Y 1 A VAL 774  ? A VAL 774  
72  1 Y 1 A LYS 775  ? A LYS 775  
73  1 Y 1 A ALA 776  ? A ALA 776  
74  1 Y 1 A LEU 777  ? A LEU 777  
75  1 Y 1 A TYR 778  ? A TYR 778  
76  1 Y 1 A ASP 779  ? A ASP 779  
77  1 Y 1 A TYR 780  ? A TYR 780  
78  1 Y 1 A LYS 781  ? A LYS 781  
79  1 Y 1 A ALA 782  ? A ALA 782  
80  1 Y 1 A LYS 783  ? A LYS 783  
81  1 Y 1 A ARG 784  ? A ARG 784  
82  1 Y 1 A SER 785  ? A SER 785  
83  1 Y 1 A ASP 786  ? A ASP 786  
84  1 Y 1 A GLU 787  ? A GLU 787  
85  1 Y 1 A LEU 788  ? A LEU 788  
86  1 Y 1 A SER 789  ? A SER 789  
87  1 Y 1 A PHE 790  ? A PHE 790  
88  1 Y 1 A CYS 791  ? A CYS 791  
89  1 Y 1 A ARG 792  ? A ARG 792  
90  1 Y 1 A GLY 793  ? A GLY 793  
91  1 Y 1 A ALA 794  ? A ALA 794  
92  1 Y 1 A LEU 795  ? A LEU 795  
93  1 Y 1 A ILE 796  ? A ILE 796  
94  1 Y 1 A HIS 797  ? A HIS 797  
95  1 Y 1 A ASN 798  ? A ASN 798  
96  1 Y 1 A VAL 799  ? A VAL 799  
97  1 Y 1 A SER 800  ? A SER 800  
98  1 Y 1 A LYS 801  ? A LYS 801  
99  1 Y 1 A GLU 802  ? A GLU 802  
100 1 Y 1 A PRO 803  ? A PRO 803  
101 1 Y 1 A GLY 804  ? A GLY 804  
102 1 Y 1 A GLY 805  ? A GLY 805  
103 1 Y 1 A TRP 806  ? A TRP 806  
104 1 Y 1 A TRP 807  ? A TRP 807  
105 1 Y 1 A LYS 808  ? A LYS 808  
106 1 Y 1 A GLY 809  ? A GLY 809  
107 1 Y 1 A ASP 810  ? A ASP 810  
108 1 Y 1 A TYR 811  ? A TYR 811  
109 1 Y 1 A GLY 812  ? A GLY 812  
110 1 Y 1 A THR 813  ? A THR 813  
111 1 Y 1 A ARG 814  ? A ARG 814  
112 1 Y 1 A ILE 815  ? A ILE 815  
113 1 Y 1 A GLN 816  ? A GLN 816  
114 1 Y 1 A GLN 817  ? A GLN 817  
115 1 Y 1 A TYR 818  ? A TYR 818  
116 1 Y 1 A PHE 819  ? A PHE 819  
117 1 Y 1 A PRO 820  ? A PRO 820  
118 1 Y 1 A SER 821  ? A SER 821  
119 1 Y 1 A ASN 822  ? A ASN 822  
120 1 Y 1 A TYR 823  ? A TYR 823  
121 1 Y 1 A VAL 824  ? A VAL 824  
122 1 Y 1 A GLU 825  ? A GLU 825  
123 1 Y 1 A ASP 826  ? A ASP 826  
124 1 Y 1 A ILE 827  ? A ILE 827  
125 1 Y 1 A SER 828  ? A SER 828  
126 1 Y 1 A THR 829  ? A THR 829  
127 1 Y 1 A ALA 830  ? A ALA 830  
128 1 Y 1 A ASP 831  ? A ASP 831  
129 1 Y 1 A PHE 832  ? A PHE 832  
130 1 Y 1 A GLU 833  ? A GLU 833  
131 1 Y 1 A LYS 909  ? A LYS 909  
132 1 Y 1 A ILE 910  ? A ILE 910  
133 1 Y 1 A ASP 911  ? A ASP 911  
134 1 Y 1 A THR 912  ? A THR 912  
135 1 Y 1 A LYS 913  ? A LYS 913  
136 1 Y 1 A GLU 914  ? A GLU 914  
137 1 Y 1 A ASN 915  ? A ASN 915  
138 1 Y 1 A ASN 916  ? A ASN 916  
139 1 Y 1 A MET 917  ? A MET 917  
140 1 Y 1 A LYS 918  ? A LYS 918  
141 1 Y 1 A TYR 919  ? A TYR 919  
142 1 Y 1 A TRP 920  ? A TRP 920  
143 1 Y 1 A GLU 921  ? A GLU 921  
144 1 Y 1 A LYS 922  ? A LYS 922  
145 1 Y 1 A ASN 923  ? A ASN 923  
146 1 Y 1 A GLU 1191 ? A GLU 1191 
147 1 Y 1 A SER 1192 ? A SER 1192 
148 1 Y 1 A GLU 1193 ? A GLU 1193 
149 1 Y 1 A GLU 1194 ? A GLU 1194 
150 1 Y 1 A GLU 1195 ? A GLU 1195 
151 1 Y 1 A LEU 1196 ? A LEU 1196 
152 1 Y 1 A TYR 1197 ? A TYR 1197 
153 1 Y 1 A SER 1198 ? A SER 1198 
154 1 Y 1 A SER 1199 ? A SER 1199 
155 1 Y 1 A CYS 1200 ? A CYS 1200 
156 1 Y 1 A ARG 1201 ? A ARG 1201 
157 1 Y 1 A GLN 1202 ? A GLN 1202 
158 1 Y 1 A LEU 1203 ? A LEU 1203 
159 1 Y 1 A ARG 1204 ? A ARG 1204 
160 1 Y 1 A ARG 1205 ? A ARG 1205 
161 1 Y 1 A ARG 1206 ? A ARG 1206 
162 1 Y 1 A GLN 1207 ? A GLN 1207 
163 1 Y 1 A GLU 1208 ? A GLU 1208 
164 1 Y 1 A GLU 1209 ? A GLU 1209 
165 1 Y 1 A LEU 1210 ? A LEU 1210 
166 1 Y 1 A ASN 1211 ? A ASN 1211 
167 1 Y 1 A ASN 1212 ? A ASN 1212 
168 1 Y 1 A GLN 1213 ? A GLN 1213 
169 1 Y 1 A LEU 1214 ? A LEU 1214 
170 1 Y 1 A PHE 1215 ? A PHE 1215 
171 1 Y 1 A LEU 1216 ? A LEU 1216 
172 1 Y 1 A TYR 1217 ? A TYR 1217 
173 1 Y 1 A ASP 1218 ? A ASP 1218 
174 1 Y 1 A THR 1219 ? A THR 1219 
175 1 Y 1 A HIS 1220 ? A HIS 1220 
176 1 Y 1 A GLN 1221 ? A GLN 1221 
177 1 Y 1 A ASN 1222 ? A ASN 1222 
178 1 Y 1 A LEU 1223 ? A LEU 1223 
179 1 Y 1 A ARG 1224 ? A ARG 1224 
180 1 Y 1 A ASN 1225 ? A ASN 1225 
181 1 Y 1 A ALA 1226 ? A ALA 1226 
182 1 Y 1 A ASN 1227 ? A ASN 1227 
183 1 Y 1 A ARG 1228 ? A ARG 1228 
184 1 Y 1 A ASP 1229 ? A ASP 1229 
185 1 Y 1 A ALA 1230 ? A ALA 1230 
186 1 Y 1 A LEU 1231 ? A LEU 1231 
187 1 Y 1 A VAL 1232 ? A VAL 1232 
188 1 Y 1 A LYS 1233 ? A LYS 1233 
189 1 Y 1 A GLU 1234 ? A GLU 1234 
190 1 Y 1 A PHE 1235 ? A PHE 1235 
191 1 Y 1 A SER 1236 ? A SER 1236 
192 1 Y 1 A VAL 1237 ? A VAL 1237 
193 1 Y 1 A ASN 1238 ? A ASN 1238 
194 1 Y 1 A GLU 1239 ? A GLU 1239 
195 1 Y 1 A ASN 1240 ? A ASN 1240 
196 1 Y 1 A GLN 1241 ? A GLN 1241 
197 1 Y 1 A LEU 1242 ? A LEU 1242 
198 1 Y 1 A GLN 1243 ? A GLN 1243 
199 1 Y 1 A LEU 1244 ? A LEU 1244 
200 1 Y 1 A TYR 1245 ? A TYR 1245 
201 1 Y 1 A GLN 1246 ? A GLN 1246 
202 1 Y 1 A GLU 1247 ? A GLU 1247 
203 1 Y 1 A LYS 1248 ? A LYS 1248 
204 1 Y 1 A CYS 1249 ? A CYS 1249 
205 1 Y 1 A ASN 1250 ? A ASN 1250 
206 1 Y 1 A LYS 1251 ? A LYS 1251 
207 1 Y 1 A ARG 1252 ? A ARG 1252 
208 1 Y 1 A LEU 1253 ? A LEU 1253 
209 1 Y 1 A ARG 1254 ? A ARG 1254 
210 1 Y 1 A GLU 1255 ? A GLU 1255 
211 1 Y 1 A LYS 1256 ? A LYS 1256 
212 1 Y 1 A ARG 1257 ? A ARG 1257 
213 1 Y 1 A VAL 1258 ? A VAL 1258 
214 1 Y 1 A SER 1259 ? A SER 1259 
215 1 Y 1 A ASN 1260 ? A ASN 1260 
216 1 Y 1 A SER 1261 ? A SER 1261 
217 1 Y 1 A LYS 1262 ? A LYS 1262 
218 1 Y 1 A PHE 1263 ? A PHE 1263 
219 1 Y 1 A TYR 1264 ? A TYR 1264 
220 1 Y 1 A SER 1265 ? A SER 1265 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-09-13 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           8QJU 
_em_admin.last_update        2025-03-26 
_em_admin.map_release_date   2025-03-26 
_em_admin.title              
'Structure of the human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) protein' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           1.5 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Medical Research Council (MRC, United Kingdom)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8QJU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 11   ? 123.429 70.262  111.724 1.00 175.17 ? 11   ALA A N   1 
ATOM 2    C CA  . ALA A 1 11   ? 123.139 69.287  112.805 1.00 178.28 ? 11   ALA A CA  1 
ATOM 3    C C   . ALA A 1 11   ? 122.611 70.019  114.035 1.00 170.43 ? 11   ALA A C   1 
ATOM 4    O O   . ALA A 1 11   ? 123.022 71.142  114.317 1.00 169.98 ? 11   ALA A O   1 
ATOM 5    C CB  . ALA A 1 11   ? 124.378 68.488  113.136 1.00 182.89 ? 11   ALA A CB  1 
ATOM 6    N N   . GLU A 1 12   ? 121.697 69.361  114.758 1.00 168.01 ? 12   GLU A N   1 
ATOM 7    C CA  . GLU A 1 12   ? 121.065 69.947  115.928 1.00 172.02 ? 12   GLU A CA  1 
ATOM 8    C C   . GLU A 1 12   ? 122.140 70.481  116.866 1.00 161.58 ? 12   GLU A C   1 
ATOM 9    O O   . GLU A 1 12   ? 122.028 71.599  117.365 1.00 162.23 ? 12   GLU A O   1 
ATOM 10   C CB  . GLU A 1 12   ? 120.192 68.922  116.654 1.00 190.82 ? 12   GLU A CB  1 
ATOM 11   C CG  . GLU A 1 12   ? 119.394 69.503  117.814 1.00 203.10 ? 12   GLU A CG  1 
ATOM 12   C CD  . GLU A 1 12   ? 118.174 70.334  117.444 1.00 213.87 ? 12   GLU A CD  1 
ATOM 13   O OE1 . GLU A 1 12   ? 117.604 70.969  118.354 1.00 223.84 ? 12   GLU A OE1 1 
ATOM 14   O OE2 . GLU A 1 12   ? 117.786 70.338  116.257 1.00 217.26 ? 12   GLU A OE2 1 
ATOM 15   N N   . TYR A 1 13   ? 123.174 69.669  117.102 1.00 172.73 ? 13   TYR A N   1 
ATOM 16   C CA  . TYR A 1 13   ? 124.307 70.139  117.875 1.00 195.85 ? 13   TYR A CA  1 
ATOM 17   C C   . TYR A 1 13   ? 124.850 71.419  117.251 1.00 197.54 ? 13   TYR A C   1 
ATOM 18   O O   . TYR A 1 13   ? 125.124 72.376  117.967 1.00 208.03 ? 13   TYR A O   1 
ATOM 19   C CB  . TYR A 1 13   ? 125.447 69.124  117.961 1.00 213.65 ? 13   TYR A CB  1 
ATOM 20   C CG  . TYR A 1 13   ? 126.683 69.717  118.591 1.00 234.35 ? 13   TYR A CG  1 
ATOM 21   C CD1 . TYR A 1 13   ? 126.690 70.088  119.926 1.00 248.25 ? 13   TYR A CD1 1 
ATOM 22   C CD2 . TYR A 1 13   ? 127.813 69.994  117.838 1.00 240.42 ? 13   TYR A CD2 1 
ATOM 23   C CE1 . TYR A 1 13   ? 127.806 70.665  120.512 1.00 251.99 ? 13   TYR A CE1 1 
ATOM 24   C CE2 . TYR A 1 13   ? 128.939 70.567  118.408 1.00 246.69 ? 13   TYR A CE2 1 
ATOM 25   C CZ  . TYR A 1 13   ? 128.936 70.906  119.751 1.00 250.04 ? 13   TYR A CZ  1 
ATOM 26   O OH  . TYR A 1 13   ? 130.044 71.479  120.330 1.00 244.00 ? 13   TYR A OH  1 
ATOM 27   N N   . GLU A 1 14   ? 125.029 71.418  115.925 1.00 191.72 ? 14   GLU A N   1 
ATOM 28   C CA  . GLU A 1 14   ? 125.606 72.575  115.260 1.00 190.19 ? 14   GLU A CA  1 
ATOM 29   C C   . GLU A 1 14   ? 124.724 73.800  115.482 1.00 165.06 ? 14   GLU A C   1 
ATOM 30   O O   . GLU A 1 14   ? 125.232 74.840  115.892 1.00 160.04 ? 14   GLU A O   1 
ATOM 31   C CB  . GLU A 1 14   ? 125.853 72.335  113.768 1.00 211.17 ? 14   GLU A CB  1 
ATOM 32   C CG  . GLU A 1 14   ? 127.324 72.179  113.419 1.00 222.91 ? 14   GLU A CG  1 
ATOM 33   C CD  . GLU A 1 14   ? 128.136 73.461  113.521 1.00 226.64 ? 14   GLU A CD  1 
ATOM 34   O OE1 . GLU A 1 14   ? 128.648 73.915  112.479 1.00 228.81 ? 14   GLU A OE1 1 
ATOM 35   O OE2 . GLU A 1 14   ? 128.262 74.000  114.640 1.00 226.81 ? 14   GLU A OE2 1 
ATOM 36   N N   . LYS A 1 15   ? 123.415 73.670  115.230 1.00 142.85 ? 15   LYS A N   1 
ATOM 37   C CA  . LYS A 1 15   ? 122.525 74.820  115.297 1.00 126.32 ? 15   LYS A CA  1 
ATOM 38   C C   . LYS A 1 15   ? 122.658 75.484  116.664 1.00 120.57 ? 15   LYS A C   1 
ATOM 39   O O   . LYS A 1 15   ? 122.914 76.682  116.744 1.00 118.01 ? 15   LYS A O   1 
ATOM 40   C CB  . LYS A 1 15   ? 121.070 74.436  115.014 1.00 117.59 ? 15   LYS A CB  1 
ATOM 41   C CG  . LYS A 1 15   ? 120.809 73.923  113.604 1.00 123.70 ? 15   LYS A CG  1 
ATOM 42   C CD  . LYS A 1 15   ? 119.394 74.161  113.109 1.00 132.10 ? 15   LYS A CD  1 
ATOM 43   C CE  . LYS A 1 15   ? 118.319 73.630  114.034 1.00 137.64 ? 15   LYS A CE  1 
ATOM 44   N NZ  . LYS A 1 15   ? 116.965 73.801  113.454 1.00 137.18 ? 15   LYS A NZ  1 
ATOM 45   N N   . SER A 1 16   ? 122.521 74.688  117.729 1.00 122.87 ? 16   SER A N   1 
ATOM 46   C CA  . SER A 1 16   ? 122.609 75.216  119.078 1.00 128.81 ? 16   SER A CA  1 
ATOM 47   C C   . SER A 1 16   ? 123.881 76.041  119.235 1.00 119.23 ? 16   SER A C   1 
ATOM 48   O O   . SER A 1 16   ? 123.834 77.125  119.809 1.00 128.35 ? 16   SER A O   1 
ATOM 49   C CB  . SER A 1 16   ? 122.542 74.128  120.114 1.00 146.83 ? 16   SER A CB  1 
ATOM 50   O OG  . SER A 1 16   ? 122.638 74.673  121.423 1.00 158.32 ? 16   SER A OG  1 
ATOM 51   N N   . GLN A 1 17   ? 125.002 75.533  118.710 1.00 119.75 ? 17   GLN A N   1 
ATOM 52   C CA  . GLN A 1 17   ? 126.273 76.220  118.859 1.00 137.86 ? 17   GLN A CA  1 
ATOM 53   C C   . GLN A 1 17   ? 126.183 77.609  118.229 1.00 150.86 ? 17   GLN A C   1 
ATOM 54   O O   . GLN A 1 17   ? 126.632 78.584  118.829 1.00 159.29 ? 17   GLN A O   1 
ATOM 55   C CB  . GLN A 1 17   ? 127.424 75.413  118.256 1.00 147.32 ? 17   GLN A CB  1 
ATOM 56   C CG  . GLN A 1 17   ? 128.788 76.063  118.440 1.00 160.42 ? 17   GLN A CG  1 
ATOM 57   C CD  . GLN A 1 17   ? 129.118 76.283  119.896 1.00 182.03 ? 17   GLN A CD  1 
ATOM 58   O OE1 . GLN A 1 17   ? 129.193 75.343  120.685 1.00 188.22 ? 17   GLN A OE1 1 
ATOM 59   N NE2 . GLN A 1 17   ? 129.317 77.538  120.267 1.00 194.16 ? 17   GLN A NE2 1 
ATOM 60   N N   . ILE A 1 18   ? 125.593 77.703  117.032 1.00 146.56 ? 18   ILE A N   1 
ATOM 61   C CA  . ILE A 1 18   ? 125.459 78.993  116.375 1.00 140.41 ? 18   ILE A CA  1 
ATOM 62   C C   . ILE A 1 18   ? 124.572 79.884  117.241 1.00 124.23 ? 18   ILE A C   1 
ATOM 63   O O   . ILE A 1 18   ? 124.938 81.015  117.526 1.00 125.22 ? 18   ILE A O   1 
ATOM 64   C CB  . ILE A 1 18   ? 124.931 78.861  114.931 1.00 156.16 ? 18   ILE A CB  1 
ATOM 65   C CG1 . ILE A 1 18   ? 125.827 77.961  114.076 1.00 175.08 ? 18   ILE A CG1 1 
ATOM 66   C CG2 . ILE A 1 18   ? 124.750 80.231  114.290 1.00 157.75 ? 18   ILE A CG2 1 
ATOM 67   C CD1 . ILE A 1 18   ? 127.269 78.417  113.993 1.00 181.22 ? 18   ILE A CD1 1 
ATOM 68   N N   . LYS A 1 19   ? 123.439 79.354  117.713 1.00 110.29 ? 19   LYS A N   1 
ATOM 69   C CA  . LYS A 1 19   ? 122.496 80.171  118.460 1.00 103.44 ? 19   LYS A CA  1 
ATOM 70   C C   . LYS A 1 19   ? 123.183 80.732  119.700 1.00 101.53 ? 19   LYS A C   1 
ATOM 71   O O   . LYS A 1 19   ? 123.011 81.906  120.012 1.00 105.82 ? 19   LYS A O   1 
ATOM 72   C CB  . LYS A 1 19   ? 121.233 79.377  118.801 1.00 103.32 ? 19   LYS A CB  1 
ATOM 73   C CG  . LYS A 1 19   ? 120.445 78.917  117.579 1.00 116.83 ? 19   LYS A CG  1 
ATOM 74   C CD  . LYS A 1 19   ? 119.225 78.072  117.894 1.00 132.61 ? 19   LYS A CD  1 
ATOM 75   C CE  . LYS A 1 19   ? 118.183 78.795  118.717 1.00 142.39 ? 19   LYS A CE  1 
ATOM 76   N NZ  . LYS A 1 19   ? 117.024 77.919  119.015 1.00 149.20 ? 19   LYS A NZ  1 
ATOM 77   N N   . ARG A 1 20   ? 123.986 79.904  120.377 1.00 106.61 ? 20   ARG A N   1 
ATOM 78   C CA  . ARG A 1 20   ? 124.692 80.328  121.575 1.00 117.41 ? 20   ARG A CA  1 
ATOM 79   C C   . ARG A 1 20   ? 125.614 81.496  121.243 1.00 109.98 ? 20   ARG A C   1 
ATOM 80   O O   . ARG A 1 20   ? 125.702 82.449  122.013 1.00 121.68 ? 20   ARG A O   1 
ATOM 81   C CB  . ARG A 1 20   ? 125.500 79.177  122.184 1.00 138.65 ? 20   ARG A CB  1 
ATOM 82   C CG  . ARG A 1 20   ? 126.289 79.544  123.436 1.00 152.82 ? 20   ARG A CG  1 
ATOM 83   C CD  . ARG A 1 20   ? 125.420 79.989  124.601 1.00 163.39 ? 20   ARG A CD  1 
ATOM 84   N NE  . ARG A 1 20   ? 124.467 78.957  124.995 1.00 177.00 ? 20   ARG A NE  1 
ATOM 85   C CZ  . ARG A 1 20   ? 123.142 79.077  124.958 1.00 187.72 ? 20   ARG A CZ  1 
ATOM 86   N NH1 . ARG A 1 20   ? 122.580 80.203  124.558 1.00 190.81 ? 20   ARG A NH1 1 
ATOM 87   N NH2 . ARG A 1 20   ? 122.379 78.063  125.327 1.00 192.67 ? 20   ARG A NH2 1 
ATOM 88   N N   . ALA A 1 21   ? 126.305 81.415  120.104 1.00 103.26 ? 21   ALA A N   1 
ATOM 89   C CA  . ALA A 1 21   ? 127.259 82.447  119.738 1.00 115.53 ? 21   ALA A CA  1 
ATOM 90   C C   . ALA A 1 21   ? 126.555 83.798  119.634 1.00 111.01 ? 21   ALA A C   1 
ATOM 91   O O   . ALA A 1 21   ? 127.093 84.801  120.097 1.00 107.29 ? 21   ALA A O   1 
ATOM 92   C CB  . ALA A 1 21   ? 127.966 82.083  118.456 1.00 129.24 ? 21   ALA A CB  1 
ATOM 93   N N   . LEU A 1 22   ? 125.346 83.818  119.053 1.00 107.60 ? 22   LEU A N   1 
ATOM 94   C CA  . LEU A 1 22   ? 124.598 85.058  118.924 1.00 112.09 ? 22   LEU A CA  1 
ATOM 95   C C   . LEU A 1 22   ? 124.212 85.587  120.305 1.00 114.75 ? 22   LEU A C   1 
ATOM 96   O O   . LEU A 1 22   ? 124.309 86.788  120.536 1.00 124.39 ? 22   LEU A O   1 
ATOM 97   C CB  . LEU A 1 22   ? 123.368 84.860  118.027 1.00 113.23 ? 22   LEU A CB  1 
ATOM 98   C CG  . LEU A 1 22   ? 123.665 84.778  116.527 1.00 124.07 ? 22   LEU A CG  1 
ATOM 99   C CD1 . LEU A 1 22   ? 124.170 83.397  116.138 1.00 133.47 ? 22   LEU A CD1 1 
ATOM 100  C CD2 . LEU A 1 22   ? 122.442 85.147  115.694 1.00 126.18 ? 22   LEU A CD2 1 
ATOM 101  N N   . GLU A 1 23   ? 123.795 84.710  121.230 1.00 106.00 ? 23   GLU A N   1 
ATOM 102  C CA  . GLU A 1 23   ? 123.245 85.175  122.497 1.00 99.57  ? 23   GLU A CA  1 
ATOM 103  C C   . GLU A 1 23   ? 124.316 85.896  123.310 1.00 84.35  ? 23   GLU A C   1 
ATOM 104  O O   . GLU A 1 23   ? 124.021 86.910  123.931 1.00 85.83  ? 23   GLU A O   1 
ATOM 105  C CB  . GLU A 1 23   ? 122.609 84.040  123.300 1.00 115.20 ? 23   GLU A CB  1 
ATOM 106  C CG  . GLU A 1 23   ? 121.368 83.459  122.640 1.00 137.45 ? 23   GLU A CG  1 
ATOM 107  C CD  . GLU A 1 23   ? 120.683 82.357  123.428 1.00 159.14 ? 23   GLU A CD  1 
ATOM 108  O OE1 . GLU A 1 23   ? 120.226 82.639  124.555 1.00 162.77 ? 23   GLU A OE1 1 
ATOM 109  O OE2 . GLU A 1 23   ? 120.616 81.215  122.917 1.00 176.85 ? 23   GLU A OE2 1 
ATOM 110  N N   . LEU A 1 24   ? 125.550 85.385  123.307 1.00 87.71  ? 24   LEU A N   1 
ATOM 111  C CA  . LEU A 1 24   ? 126.635 86.069  123.989 1.00 106.38 ? 24   LEU A CA  1 
ATOM 112  C C   . LEU A 1 24   ? 126.806 87.442  123.353 1.00 101.11 ? 24   LEU A C   1 
ATOM 113  O O   . LEU A 1 24   ? 126.632 88.458  124.020 1.00 102.63 ? 24   LEU A O   1 
ATOM 114  C CB  . LEU A 1 24   ? 127.927 85.248  123.902 1.00 134.49 ? 24   LEU A CB  1 
ATOM 115  C CG  . LEU A 1 24   ? 127.869 83.844  124.508 1.00 166.56 ? 24   LEU A CG  1 
ATOM 116  C CD1 . LEU A 1 24   ? 129.270 83.282  124.702 1.00 182.19 ? 24   LEU A CD1 1 
ATOM 117  C CD2 . LEU A 1 24   ? 127.101 83.831  125.824 1.00 175.89 ? 24   LEU A CD2 1 
ATOM 118  N N   . GLY A 1 25   ? 127.117 87.451  122.053 1.00 104.47 ? 25   GLY A N   1 
ATOM 119  C CA  . GLY A 1 25   ? 127.211 88.681  121.287 1.00 106.61 ? 25   GLY A CA  1 
ATOM 120  C C   . GLY A 1 25   ? 128.650 89.011  120.911 1.00 109.85 ? 25   GLY A C   1 
ATOM 121  O O   . GLY A 1 25   ? 129.590 88.567  121.568 1.00 126.83 ? 25   GLY A O   1 
ATOM 122  N N   . THR A 1 26   ? 128.786 89.809  119.848 1.00 100.30 ? 26   THR A N   1 
ATOM 123  C CA  . THR A 1 26   ? 130.075 90.177  119.295 1.00 99.95  ? 26   THR A CA  1 
ATOM 124  C C   . THR A 1 26   ? 130.089 91.681  119.079 1.00 88.17  ? 26   THR A C   1 
ATOM 125  O O   . THR A 1 26   ? 129.038 92.275  118.873 1.00 94.53  ? 26   THR A O   1 
ATOM 126  C CB  . THR A 1 26   ? 130.313 89.461  117.960 1.00 117.09 ? 26   THR A CB  1 
ATOM 127  O OG1 . THR A 1 26   ? 129.249 88.527  117.759 1.00 114.99 ? 26   THR A OG1 1 
ATOM 128  C CG2 . THR A 1 26   ? 131.659 88.774  117.891 1.00 128.60 ? 26   THR A CG2 1 
ATOM 129  N N   . VAL A 1 27   ? 131.272 92.290  119.127 1.00 84.40  ? 27   VAL A N   1 
ATOM 130  C CA  . VAL A 1 27   ? 131.385 93.698  118.798 1.00 89.92  ? 27   VAL A CA  1 
ATOM 131  C C   . VAL A 1 27   ? 131.421 93.826  117.281 1.00 96.04  ? 27   VAL A C   1 
ATOM 132  O O   . VAL A 1 27   ? 132.389 93.412  116.647 1.00 103.01 ? 27   VAL A O   1 
ATOM 133  C CB  . VAL A 1 27   ? 132.628 94.339  119.434 1.00 101.70 ? 27   VAL A CB  1 
ATOM 134  C CG1 . VAL A 1 27   ? 132.818 95.767  118.952 1.00 106.36 ? 27   VAL A CG1 1 
ATOM 135  C CG2 . VAL A 1 27   ? 132.572 94.279  120.952 1.00 110.49 ? 27   VAL A CG2 1 
ATOM 136  N N   . MET A 1 28   ? 130.364 94.414  116.707 1.00 95.37  ? 28   MET A N   1 
ATOM 137  C CA  . MET A 1 28   ? 130.321 94.636  115.271 1.00 89.60  ? 28   MET A CA  1 
ATOM 138  C C   . MET A 1 28   ? 129.891 96.067  114.969 1.00 86.41  ? 28   MET A C   1 
ATOM 139  O O   . MET A 1 28   ? 128.747 96.436  115.231 1.00 87.39  ? 28   MET A O   1 
ATOM 140  C CB  . MET A 1 28   ? 129.377 93.667  114.561 1.00 83.54  ? 28   MET A CB  1 
ATOM 141  C CG  . MET A 1 28   ? 128.407 92.965  115.460 1.00 89.49  ? 28   MET A CG  1 
ATOM 142  S SD  . MET A 1 28   ? 127.665 91.607  114.545 1.00 109.58 ? 28   MET A SD  1 
ATOM 143  C CE  . MET A 1 28   ? 129.011 90.426  114.645 1.00 117.31 ? 28   MET A CE  1 
ATOM 144  N N   . THR A 1 29   ? 130.822 96.838  114.387 1.00 75.95  ? 29   THR A N   1 
ATOM 145  C CA  . THR A 1 29   ? 130.588 98.215  113.991 1.00 68.37  ? 29   THR A CA  1 
ATOM 146  C C   . THR A 1 29   ? 129.208 98.360  113.365 1.00 68.47  ? 29   THR A C   1 
ATOM 147  O O   . THR A 1 29   ? 128.793 97.495  112.603 1.00 79.28  ? 29   THR A O   1 
ATOM 148  C CB  . THR A 1 29   ? 131.650 98.684  112.996 1.00 71.99  ? 29   THR A CB  1 
ATOM 149  O OG1 . THR A 1 29   ? 132.930 98.424  113.573 1.00 79.32  ? 29   THR A OG1 1 
ATOM 150  C CG2 . THR A 1 29   ? 131.514 100.150 112.652 1.00 77.90  ? 29   THR A CG2 1 
ATOM 151  N N   . VAL A 1 30   ? 128.520 99.463  113.683 1.00 69.95  ? 30   VAL A N   1 
ATOM 152  C CA  . VAL A 1 30   ? 127.200 99.741  113.140 1.00 80.65  ? 30   VAL A CA  1 
ATOM 153  C C   . VAL A 1 30   ? 127.255 101.060 112.366 1.00 96.27  ? 30   VAL A C   1 
ATOM 154  O O   . VAL A 1 30   ? 127.516 102.113 112.948 1.00 103.87 ? 30   VAL A O   1 
ATOM 155  C CB  . VAL A 1 30   ? 126.132 99.789  114.249 1.00 82.87  ? 30   VAL A CB  1 
ATOM 156  C CG1 . VAL A 1 30   ? 124.754 100.120 113.692 1.00 86.74  ? 30   VAL A CG1 1 
ATOM 157  C CG2 . VAL A 1 30   ? 126.090 98.499  115.052 1.00 83.83  ? 30   VAL A CG2 1 
ATOM 158  N N   . PHE A 1 31   ? 127.002 100.976 111.049 1.00 93.21  ? 31   PHE A N   1 
ATOM 159  C CA  . PHE A 1 31   ? 126.924 102.130 110.169 1.00 87.76  ? 31   PHE A CA  1 
ATOM 160  C C   . PHE A 1 31   ? 125.458 102.460 109.911 1.00 91.57  ? 31   PHE A C   1 
ATOM 161  O O   . PHE A 1 31   ? 124.645 101.555 109.736 1.00 90.39  ? 31   PHE A O   1 
ATOM 162  C CB  . PHE A 1 31   ? 127.553 101.836 108.805 1.00 88.44  ? 31   PHE A CB  1 
ATOM 163  C CG  . PHE A 1 31   ? 129.052 101.679 108.742 1.00 96.43  ? 31   PHE A CG  1 
ATOM 164  C CD1 . PHE A 1 31   ? 129.901 102.760 108.933 1.00 111.54 ? 31   PHE A CD1 1 
ATOM 165  C CD2 . PHE A 1 31   ? 129.612 100.456 108.414 1.00 98.84  ? 31   PHE A CD2 1 
ATOM 166  C CE1 . PHE A 1 31   ? 131.276 102.606 108.823 1.00 122.72 ? 31   PHE A CE1 1 
ATOM 167  C CE2 . PHE A 1 31   ? 130.986 100.301 108.318 1.00 110.78 ? 31   PHE A CE2 1 
ATOM 168  C CZ  . PHE A 1 31   ? 131.817 101.375 108.523 1.00 119.71 ? 31   PHE A CZ  1 
ATOM 169  N N   . SER A 1 32   ? 125.140 103.758 109.905 1.00 106.36 ? 32   SER A N   1 
ATOM 170  C CA  . SER A 1 32   ? 123.897 104.269 109.347 1.00 123.48 ? 32   SER A CA  1 
ATOM 171  C C   . SER A 1 32   ? 124.210 105.550 108.579 1.00 138.14 ? 32   SER A C   1 
ATOM 172  O O   . SER A 1 32   ? 125.238 106.176 108.823 1.00 146.24 ? 32   SER A O   1 
ATOM 173  C CB  . SER A 1 32   ? 122.850 104.496 110.414 1.00 124.83 ? 32   SER A CB  1 
ATOM 174  O OG  . SER A 1 32   ? 122.297 103.267 110.865 1.00 119.88 ? 32   SER A OG  1 
ATOM 175  N N   . PHE A 1 33   ? 123.332 105.947 107.652 1.00 147.83 ? 33   PHE A N   1 
ATOM 176  C CA  . PHE A 1 33   ? 123.599 107.154 106.885 1.00 159.86 ? 33   PHE A CA  1 
ATOM 177  C C   . PHE A 1 33   ? 123.613 108.343 107.844 1.00 160.26 ? 33   PHE A C   1 
ATOM 178  O O   . PHE A 1 33   ? 124.470 109.214 107.736 1.00 157.73 ? 33   PHE A O   1 
ATOM 179  C CB  . PHE A 1 33   ? 122.674 107.274 105.666 1.00 170.67 ? 33   PHE A CB  1 
ATOM 180  C CG  . PHE A 1 33   ? 121.186 107.335 105.914 1.00 177.31 ? 33   PHE A CG  1 
ATOM 181  C CD1 . PHE A 1 33   ? 120.613 108.410 106.575 1.00 185.49 ? 33   PHE A CD1 1 
ATOM 182  C CD2 . PHE A 1 33   ? 120.348 106.344 105.418 1.00 187.12 ? 33   PHE A CD2 1 
ATOM 183  C CE1 . PHE A 1 33   ? 119.240 108.475 106.758 1.00 198.08 ? 33   PHE A CE1 1 
ATOM 184  C CE2 . PHE A 1 33   ? 118.978 106.403 105.618 1.00 190.72 ? 33   PHE A CE2 1 
ATOM 185  C CZ  . PHE A 1 33   ? 118.426 107.470 106.286 1.00 199.07 ? 33   PHE A CZ  1 
ATOM 186  N N   . ARG A 1 34   ? 122.724 108.315 108.841 1.00 166.86 ? 34   ARG A N   1 
ATOM 187  C CA  . ARG A 1 34   ? 122.766 109.282 109.924 1.00 172.27 ? 34   ARG A CA  1 
ATOM 188  C C   . ARG A 1 34   ? 123.964 108.927 110.800 1.00 156.04 ? 34   ARG A C   1 
ATOM 189  O O   . ARG A 1 34   ? 124.432 107.791 110.772 1.00 150.09 ? 34   ARG A O   1 
ATOM 190  C CB  . ARG A 1 34   ? 121.469 109.286 110.747 1.00 184.22 ? 34   ARG A CB  1 
ATOM 191  C CG  . ARG A 1 34   ? 120.370 108.368 110.228 1.00 193.56 ? 34   ARG A CG  1 
ATOM 192  C CD  . ARG A 1 34   ? 119.035 109.044 110.057 1.00 200.37 ? 34   ARG A CD  1 
ATOM 193  N NE  . ARG A 1 34   ? 118.100 108.095 109.468 1.00 204.58 ? 34   ARG A NE  1 
ATOM 194  C CZ  . ARG A 1 34   ? 116.869 107.876 109.905 1.00 207.02 ? 34   ARG A CZ  1 
ATOM 195  N NH1 . ARG A 1 34   ? 116.440 108.481 110.997 1.00 212.91 ? 34   ARG A NH1 1 
ATOM 196  N NH2 . ARG A 1 34   ? 116.078 107.037 109.258 1.00 205.51 ? 34   ARG A NH2 1 
ATOM 197  N N   . LYS A 1 35   ? 124.461 109.921 111.543 1.00 154.09 ? 35   LYS A N   1 
ATOM 198  C CA  . LYS A 1 35   ? 125.478 109.735 112.570 1.00 160.20 ? 35   LYS A CA  1 
ATOM 199  C C   . LYS A 1 35   ? 126.879 109.665 111.959 1.00 156.47 ? 35   LYS A C   1 
ATOM 200  O O   . LYS A 1 35   ? 127.837 109.384 112.676 1.00 157.78 ? 35   LYS A O   1 
ATOM 201  C CB  . LYS A 1 35   ? 125.196 108.501 113.437 1.00 165.16 ? 35   LYS A CB  1 
ATOM 202  C CG  . LYS A 1 35   ? 123.831 108.481 114.116 1.00 165.13 ? 35   LYS A CG  1 
ATOM 203  C CD  . LYS A 1 35   ? 123.682 107.393 115.158 1.00 169.00 ? 35   LYS A CD  1 
ATOM 204  C CE  . LYS A 1 35   ? 123.704 105.994 114.578 1.00 172.90 ? 35   LYS A CE  1 
ATOM 205  N NZ  . LYS A 1 35   ? 123.609 104.955 115.632 1.00 171.32 ? 35   LYS A NZ  1 
ATOM 206  N N   . SER A 1 36   ? 127.007 109.940 110.654 1.00 155.16 ? 36   SER A N   1 
ATOM 207  C CA  . SER A 1 36   ? 128.307 110.095 110.020 1.00 161.99 ? 36   SER A CA  1 
ATOM 208  C C   . SER A 1 36   ? 129.204 108.892 110.322 1.00 170.30 ? 36   SER A C   1 
ATOM 209  O O   . SER A 1 36   ? 128.816 107.758 110.064 1.00 180.02 ? 36   SER A O   1 
ATOM 210  C CB  . SER A 1 36   ? 128.949 111.391 110.448 1.00 162.05 ? 36   SER A CB  1 
ATOM 211  O OG  . SER A 1 36   ? 129.438 111.301 111.779 1.00 161.37 ? 36   SER A OG  1 
ATOM 212  N N   . THR A 1 37   ? 130.390 109.161 110.889 1.00 165.33 ? 37   THR A N   1 
ATOM 213  C CA  . THR A 1 37   ? 131.428 108.169 111.131 1.00 160.31 ? 37   THR A CA  1 
ATOM 214  C C   . THR A 1 37   ? 130.906 106.980 111.941 1.00 160.74 ? 37   THR A C   1 
ATOM 215  O O   . THR A 1 37   ? 130.053 107.138 112.811 1.00 165.58 ? 37   THR A O   1 
ATOM 216  C CB  . THR A 1 37   ? 132.636 108.805 111.836 1.00 158.76 ? 37   THR A CB  1 
ATOM 217  O OG1 . THR A 1 37   ? 133.328 107.770 112.535 1.00 160.36 ? 37   THR A OG1 1 
ATOM 218  C CG2 . THR A 1 37   ? 132.273 109.895 112.822 1.00 160.83 ? 37   THR A CG2 1 
ATOM 219  N N   . PRO A 1 38   ? 131.453 105.761 111.720 1.00 161.94 ? 38   PRO A N   1 
ATOM 220  C CA  . PRO A 1 38   ? 131.011 104.555 112.428 1.00 159.97 ? 38   PRO A CA  1 
ATOM 221  C C   . PRO A 1 38   ? 131.262 104.507 113.933 1.00 168.05 ? 38   PRO A C   1 
ATOM 222  O O   . PRO A 1 38   ? 132.216 105.092 114.438 1.00 177.18 ? 38   PRO A O   1 
ATOM 223  C CB  . PRO A 1 38   ? 131.898 103.451 111.841 1.00 165.02 ? 38   PRO A CB  1 
ATOM 224  C CG  . PRO A 1 38   ? 133.116 104.192 111.345 1.00 167.73 ? 38   PRO A CG  1 
ATOM 225  C CD  . PRO A 1 38   ? 132.544 105.471 110.775 1.00 169.52 ? 38   PRO A CD  1 
ATOM 226  N N   . GLU A 1 39   ? 130.438 103.711 114.611 1.00 165.26 ? 39   GLU A N   1 
ATOM 227  C CA  . GLU A 1 39   ? 130.495 103.513 116.049 1.00 169.31 ? 39   GLU A CA  1 
ATOM 228  C C   . GLU A 1 39   ? 130.416 102.009 116.279 1.00 157.27 ? 39   GLU A C   1 
ATOM 229  O O   . GLU A 1 39   ? 129.798 101.334 115.469 1.00 160.14 ? 39   GLU A O   1 
ATOM 230  C CB  . GLU A 1 39   ? 129.314 104.248 116.681 1.00 187.56 ? 39   GLU A CB  1 
ATOM 231  C CG  . GLU A 1 39   ? 127.982 103.884 116.036 1.00 197.56 ? 39   GLU A CG  1 
ATOM 232  C CD  . GLU A 1 39   ? 126.776 104.701 116.475 1.00 206.18 ? 39   GLU A CD  1 
ATOM 233  O OE1 . GLU A 1 39   ? 125.830 104.109 117.030 1.00 202.77 ? 39   GLU A OE1 1 
ATOM 234  O OE2 . GLU A 1 39   ? 126.764 105.924 116.237 1.00 213.71 ? 39   GLU A OE2 1 
ATOM 235  N N   . ARG A 1 40   ? 131.007 101.466 117.347 1.00 138.16 ? 40   ARG A N   1 
ATOM 236  C CA  . ARG A 1 40   ? 130.893 100.028 117.566 1.00 126.02 ? 40   ARG A CA  1 
ATOM 237  C C   . ARG A 1 40   ? 130.048 99.775  118.809 1.00 109.86 ? 40   ARG A C   1 
ATOM 238  O O   . ARG A 1 40   ? 130.348 100.284 119.884 1.00 114.29 ? 40   ARG A O   1 
ATOM 239  C CB  . ARG A 1 40   ? 132.249 99.315  117.615 1.00 127.54 ? 40   ARG A CB  1 
ATOM 240  C CG  . ARG A 1 40   ? 133.163 99.703  118.766 1.00 143.53 ? 40   ARG A CG  1 
ATOM 241  C CD  . ARG A 1 40   ? 133.699 101.118 118.693 1.00 156.54 ? 40   ARG A CD  1 
ATOM 242  N NE  . ARG A 1 40   ? 134.318 101.425 117.407 1.00 170.33 ? 40   ARG A NE  1 
ATOM 243  C CZ  . ARG A 1 40   ? 135.617 101.648 117.214 1.00 199.36 ? 40   ARG A CZ  1 
ATOM 244  N NH1 . ARG A 1 40   ? 136.466 101.609 118.227 1.00 207.98 ? 40   ARG A NH1 1 
ATOM 245  N NH2 . ARG A 1 40   ? 136.064 101.903 115.996 1.00 212.23 ? 40   ARG A NH2 1 
ATOM 246  N N   . ARG A 1 41   ? 128.961 99.022  118.618 1.00 98.46  ? 41   ARG A N   1 
ATOM 247  C CA  . ARG A 1 41   ? 128.018 98.704  119.676 1.00 94.36  ? 41   ARG A CA  1 
ATOM 248  C C   . ARG A 1 41   ? 127.799 97.199  119.675 1.00 89.95  ? 41   ARG A C   1 
ATOM 249  O O   . ARG A 1 41   ? 127.493 96.637  118.632 1.00 90.05  ? 41   ARG A O   1 
ATOM 250  C CB  . ARG A 1 41   ? 126.696 99.437  119.433 1.00 98.05  ? 41   ARG A CB  1 
ATOM 251  C CG  . ARG A 1 41   ? 126.872 100.924 119.157 1.00 104.63 ? 41   ARG A CG  1 
ATOM 252  C CD  . ARG A 1 41   ? 125.586 101.724 119.295 1.00 114.05 ? 41   ARG A CD  1 
ATOM 253  N NE  . ARG A 1 41   ? 125.790 103.167 119.235 1.00 118.30 ? 41   ARG A NE  1 
ATOM 254  C CZ  . ARG A 1 41   ? 126.586 103.877 120.031 1.00 125.31 ? 41   ARG A CZ  1 
ATOM 255  N NH1 . ARG A 1 41   ? 127.247 103.310 121.027 1.00 122.87 ? 41   ARG A NH1 1 
ATOM 256  N NH2 . ARG A 1 41   ? 126.703 105.178 119.825 1.00 139.45 ? 41   ARG A NH2 1 
ATOM 257  N N   . THR A 1 42   ? 127.970 96.551  120.831 1.00 86.98  ? 42   THR A N   1 
ATOM 258  C CA  . THR A 1 42   ? 127.884 95.102  120.883 1.00 84.02  ? 42   THR A CA  1 
ATOM 259  C C   . THR A 1 42   ? 126.483 94.691  120.456 1.00 60.96  ? 42   THR A C   1 
ATOM 260  O O   . THR A 1 42   ? 125.525 95.328  120.852 1.00 55.45  ? 42   THR A O   1 
ATOM 261  C CB  . THR A 1 42   ? 128.220 94.553  122.276 1.00 102.72 ? 42   THR A CB  1 
ATOM 262  O OG1 . THR A 1 42   ? 129.508 95.046  122.651 1.00 106.01 ? 42   THR A OG1 1 
ATOM 263  C CG2 . THR A 1 42   ? 128.193 93.039  122.324 1.00 111.25 ? 42   THR A CG2 1 
ATOM 264  N N   . VAL A 1 43   ? 126.384 93.655  119.628 1.00 52.75  ? 43   VAL A N   1 
ATOM 265  C CA  . VAL A 1 43   ? 125.110 93.194  119.119 1.00 55.24  ? 43   VAL A CA  1 
ATOM 266  C C   . VAL A 1 43   ? 124.842 91.819  119.709 1.00 57.31  ? 43   VAL A C   1 
ATOM 267  O O   . VAL A 1 43   ? 125.728 90.975  119.712 1.00 71.30  ? 43   VAL A O   1 
ATOM 268  C CB  . VAL A 1 43   ? 125.125 93.151  117.583 1.00 70.97  ? 43   VAL A CB  1 
ATOM 269  C CG1 . VAL A 1 43   ? 123.807 92.649  117.007 1.00 78.43  ? 43   VAL A CG1 1 
ATOM 270  C CG2 . VAL A 1 43   ? 125.477 94.509  116.994 1.00 79.96  ? 43   VAL A CG2 1 
ATOM 271  N N   . GLN A 1 44   ? 123.629 91.622  120.233 1.00 57.77  ? 44   GLN A N   1 
ATOM 272  C CA  . GLN A 1 44   ? 123.235 90.385  120.890 1.00 59.64  ? 44   GLN A CA  1 
ATOM 273  C C   . GLN A 1 44   ? 121.885 89.966  120.356 1.00 49.79  ? 44   GLN A C   1 
ATOM 274  O O   . GLN A 1 44   ? 121.107 90.812  119.943 1.00 55.29  ? 44   GLN A O   1 
ATOM 275  C CB  . GLN A 1 44   ? 123.032 90.566  122.394 1.00 80.38  ? 44   GLN A CB  1 
ATOM 276  C CG  . GLN A 1 44   ? 124.296 90.916  123.165 1.00 110.62 ? 44   GLN A CG  1 
ATOM 277  C CD  . GLN A 1 44   ? 124.002 91.175  124.623 1.00 139.04 ? 44   GLN A CD  1 
ATOM 278  O OE1 . GLN A 1 44   ? 123.354 90.376  125.300 1.00 145.73 ? 44   GLN A OE1 1 
ATOM 279  N NE2 . GLN A 1 44   ? 124.468 92.311  125.116 1.00 151.50 ? 44   GLN A NE2 1 
ATOM 280  N N   . VAL A 1 45   ? 121.611 88.671  120.398 1.00 48.97  ? 45   VAL A N   1 
ATOM 281  C CA  . VAL A 1 45   ? 120.245 88.203  120.298 1.00 55.63  ? 45   VAL A CA  1 
ATOM 282  C C   . VAL A 1 45   ? 119.786 87.882  121.713 1.00 65.62  ? 45   VAL A C   1 
ATOM 283  O O   . VAL A 1 45   ? 120.389 87.050  122.388 1.00 84.59  ? 45   VAL A O   1 
ATOM 284  C CB  . VAL A 1 45   ? 120.110 86.986  119.366 1.00 61.78  ? 45   VAL A CB  1 
ATOM 285  C CG1 . VAL A 1 45   ? 118.779 86.273  119.560 1.00 64.13  ? 45   VAL A CG1 1 
ATOM 286  C CG2 . VAL A 1 45   ? 120.309 87.375  117.906 1.00 65.48  ? 45   VAL A CG2 1 
ATOM 287  N N   . ILE A 1 46   ? 118.739 88.580  122.160 1.00 63.68  ? 46   ILE A N   1 
ATOM 288  C CA  . ILE A 1 46   ? 118.142 88.340  123.460 1.00 60.65  ? 46   ILE A CA  1 
ATOM 289  C C   . ILE A 1 46   ? 117.003 87.356  123.248 1.00 52.66  ? 46   ILE A C   1 
ATOM 290  O O   . ILE A 1 46   ? 115.954 87.759  122.781 1.00 51.87  ? 46   ILE A O   1 
ATOM 291  C CB  . ILE A 1 46   ? 117.670 89.675  124.070 1.00 64.70  ? 46   ILE A CB  1 
ATOM 292  C CG1 . ILE A 1 46   ? 118.781 90.730  124.050 1.00 70.61  ? 46   ILE A CG1 1 
ATOM 293  C CG2 . ILE A 1 46   ? 117.101 89.464  125.466 1.00 70.91  ? 46   ILE A CG2 1 
ATOM 294  C CD1 . ILE A 1 46   ? 118.375 92.061  124.631 1.00 76.60  ? 46   ILE A CD1 1 
ATOM 295  N N   . MET A 1 47   ? 117.214 86.080  123.580 1.00 61.17  ? 47   MET A N   1 
ATOM 296  C CA  . MET A 1 47   ? 116.324 85.019  123.140 1.00 83.57  ? 47   MET A CA  1 
ATOM 297  C C   . MET A 1 47   ? 114.897 85.138  123.695 1.00 92.72  ? 47   MET A C   1 
ATOM 298  O O   . MET A 1 47   ? 113.941 84.884  122.957 1.00 102.09 ? 47   MET A O   1 
ATOM 299  C CB  . MET A 1 47   ? 116.902 83.651  123.511 1.00 104.03 ? 47   MET A CB  1 
ATOM 300  C CG  . MET A 1 47   ? 117.487 82.932  122.327 1.00 122.38 ? 47   MET A CG  1 
ATOM 301  S SD  . MET A 1 47   ? 116.136 82.485  121.195 1.00 140.31 ? 47   MET A SD  1 
ATOM 302  C CE  . MET A 1 47   ? 116.941 81.214  120.227 1.00 148.42 ? 47   MET A CE  1 
ATOM 303  N N   . GLU A 1 48   ? 114.718 85.451  124.985 1.00 89.55  ? 48   GLU A N   1 
ATOM 304  C CA  . GLU A 1 48   ? 113.367 85.502  125.532 1.00 91.46  ? 48   GLU A CA  1 
ATOM 305  C C   . GLU A 1 48   ? 112.565 86.588  124.808 1.00 84.67  ? 48   GLU A C   1 
ATOM 306  O O   . GLU A 1 48   ? 111.410 86.369  124.453 1.00 72.86  ? 48   GLU A O   1 
ATOM 307  C CB  . GLU A 1 48   ? 113.363 85.641  127.060 1.00 106.47 ? 48   GLU A CB  1 
ATOM 308  C CG  . GLU A 1 48   ? 114.070 86.870  127.619 1.00 118.86 ? 48   GLU A CG  1 
ATOM 309  C CD  . GLU A 1 48   ? 115.580 86.865  127.479 1.00 129.57 ? 48   GLU A CD  1 
ATOM 310  O OE1 . GLU A 1 48   ? 116.284 86.873  128.511 1.00 135.89 ? 48   GLU A OE1 1 
ATOM 311  O OE2 . GLU A 1 48   ? 116.042 86.845  126.335 1.00 126.94 ? 48   GLU A OE2 1 
ATOM 312  N N   . THR A 1 49   ? 113.204 87.732  124.532 1.00 88.78  ? 49   THR A N   1 
ATOM 313  C CA  . THR A 1 49   ? 112.568 88.835  123.823 1.00 91.59  ? 49   THR A CA  1 
ATOM 314  C C   . THR A 1 49   ? 112.282 88.472  122.364 1.00 83.37  ? 49   THR A C   1 
ATOM 315  O O   . THR A 1 49   ? 111.285 88.923  121.820 1.00 87.96  ? 49   THR A O   1 
ATOM 316  C CB  . THR A 1 49   ? 113.421 90.112  123.884 1.00 101.98 ? 49   THR A CB  1 
ATOM 317  O OG1 . THR A 1 49   ? 114.678 89.855  123.252 1.00 105.75 ? 49   THR A OG1 1 
ATOM 318  C CG2 . THR A 1 49   ? 113.643 90.611  125.296 1.00 106.60 ? 49   THR A CG2 1 
ATOM 319  N N   . ARG A 1 50   ? 113.164 87.678  121.738 1.00 78.12  ? 50   ARG A N   1 
ATOM 320  C CA  . ARG A 1 50   ? 113.128 87.374  120.312 1.00 67.07  ? 50   ARG A CA  1 
ATOM 321  C C   . ARG A 1 50   ? 113.641 88.587  119.546 1.00 57.76  ? 50   ARG A C   1 
ATOM 322  O O   . ARG A 1 50   ? 113.482 88.655  118.336 1.00 76.23  ? 50   ARG A O   1 
ATOM 323  C CB  . ARG A 1 50   ? 111.741 86.949  119.808 1.00 67.55  ? 50   ARG A CB  1 
ATOM 324  C CG  . ARG A 1 50   ? 111.138 85.758  120.537 1.00 73.98  ? 50   ARG A CG  1 
ATOM 325  C CD  . ARG A 1 50   ? 111.986 84.513  120.501 1.00 86.94  ? 50   ARG A CD  1 
ATOM 326  N NE  . ARG A 1 50   ? 112.250 84.070  119.146 1.00 109.15 ? 50   ARG A NE  1 
ATOM 327  C CZ  . ARG A 1 50   ? 111.967 82.857  118.686 1.00 139.74 ? 50   ARG A CZ  1 
ATOM 328  N NH1 . ARG A 1 50   ? 112.321 82.516  117.456 1.00 155.05 ? 50   ARG A NH1 1 
ATOM 329  N NH2 . ARG A 1 50   ? 111.345 81.983  119.461 1.00 138.09 ? 50   ARG A NH2 1 
ATOM 330  N N   . GLN A 1 51   ? 114.310 89.498  120.257 1.00 50.38  ? 51   GLN A N   1 
ATOM 331  C CA  . GLN A 1 51   ? 114.806 90.737  119.690 1.00 53.70  ? 51   GLN A CA  1 
ATOM 332  C C   . GLN A 1 51   ? 116.320 90.690  119.506 1.00 50.01  ? 51   GLN A C   1 
ATOM 333  O O   . GLN A 1 51   ? 116.988 89.912  120.179 1.00 63.43  ? 51   GLN A O   1 
ATOM 334  C CB  . GLN A 1 51   ? 114.499 91.890  120.643 1.00 65.00  ? 51   GLN A CB  1 
ATOM 335  C CG  . GLN A 1 51   ? 113.020 92.056  120.958 1.00 75.43  ? 51   GLN A CG  1 
ATOM 336  C CD  . GLN A 1 51   ? 112.817 93.220  121.898 1.00 86.79  ? 51   GLN A CD  1 
ATOM 337  O OE1 . GLN A 1 51   ? 113.326 93.233  123.018 1.00 86.94  ? 51   GLN A OE1 1 
ATOM 338  N NE2 . GLN A 1 51   ? 112.065 94.209  121.443 1.00 94.38  ? 51   GLN A NE2 1 
ATOM 339  N N   . VAL A 1 52   ? 116.847 91.562  118.635 1.00 44.51  ? 52   VAL A N   1 
ATOM 340  C CA  . VAL A 1 52   ? 118.277 91.811  118.489 1.00 44.81  ? 52   VAL A CA  1 
ATOM 341  C C   . VAL A 1 52   ? 118.578 93.206  119.018 1.00 43.81  ? 52   VAL A C   1 
ATOM 342  O O   . VAL A 1 52   ? 117.843 94.117  118.688 1.00 53.48  ? 52   VAL A O   1 
ATOM 343  C CB  . VAL A 1 52   ? 118.691 91.723  117.008 1.00 50.41  ? 52   VAL A CB  1 
ATOM 344  C CG1 . VAL A 1 52   ? 120.078 92.305  116.762 1.00 52.53  ? 52   VAL A CG1 1 
ATOM 345  C CG2 . VAL A 1 52   ? 118.602 90.306  116.466 1.00 56.45  ? 52   VAL A CG2 1 
ATOM 346  N N   . ALA A 1 53   ? 119.676 93.417  119.749 1.00 46.05  ? 53   ALA A N   1 
ATOM 347  C CA  . ALA A 1 53   ? 119.880 94.711  120.385 1.00 53.68  ? 53   ALA A CA  1 
ATOM 348  C C   . ALA A 1 53   ? 121.346 95.128  120.384 1.00 56.64  ? 53   ALA A C   1 
ATOM 349  O O   . ALA A 1 53   ? 122.218 94.291  120.585 1.00 66.97  ? 53   ALA A O   1 
ATOM 350  C CB  . ALA A 1 53   ? 119.340 94.661  121.793 1.00 61.22  ? 53   ALA A CB  1 
ATOM 351  N N   . TRP A 1 54   ? 121.603 96.432  120.209 1.00 60.86  ? 54   TRP A N   1 
ATOM 352  C CA  . TRP A 1 54   ? 122.969 96.940  120.225 1.00 74.09  ? 54   TRP A CA  1 
ATOM 353  C C   . TRP A 1 54   ? 123.173 97.855  121.425 1.00 80.38  ? 54   TRP A C   1 
ATOM 354  O O   . TRP A 1 54   ? 122.447 98.823  121.589 1.00 91.95  ? 54   TRP A O   1 
ATOM 355  C CB  . TRP A 1 54   ? 123.402 97.608  118.903 1.00 76.58  ? 54   TRP A CB  1 
ATOM 356  C CG  . TRP A 1 54   ? 122.491 98.637  118.314 1.00 72.20  ? 54   TRP A CG  1 
ATOM 357  C CD1 . TRP A 1 54   ? 122.776 99.956  118.131 1.00 77.24  ? 54   TRP A CD1 1 
ATOM 358  C CD2 . TRP A 1 54   ? 121.195 98.425  117.733 1.00 65.21  ? 54   TRP A CD2 1 
ATOM 359  N NE1 . TRP A 1 54   ? 121.728 100.588 117.521 1.00 78.22  ? 54   TRP A NE1 1 
ATOM 360  C CE2 . TRP A 1 54   ? 120.741 99.674  117.274 1.00 70.83  ? 54   TRP A CE2 1 
ATOM 361  C CE3 . TRP A 1 54   ? 120.361 97.317  117.579 1.00 67.62  ? 54   TRP A CE3 1 
ATOM 362  C CZ2 . TRP A 1 54   ? 119.497 99.838  116.670 1.00 79.35  ? 54   TRP A CZ2 1 
ATOM 363  C CZ3 . TRP A 1 54   ? 119.131 97.485  116.993 1.00 70.18  ? 54   TRP A CZ3 1 
ATOM 364  C CH2 . TRP A 1 54   ? 118.702 98.726  116.545 1.00 75.19  ? 54   TRP A CH2 1 
ATOM 365  N N   . SER A 1 55   ? 124.181 97.535  122.244 1.00 86.40  ? 55   SER A N   1 
ATOM 366  C CA  . SER A 1 55   ? 124.438 98.219  123.502 1.00 96.09  ? 55   SER A CA  1 
ATOM 367  C C   . SER A 1 55   ? 125.783 98.931  123.444 1.00 100.57 ? 55   SER A C   1 
ATOM 368  O O   . SER A 1 55   ? 126.777 98.297  123.106 1.00 113.07 ? 55   SER A O   1 
ATOM 369  C CB  . SER A 1 55   ? 124.443 97.223  124.620 1.00 110.89 ? 55   SER A CB  1 
ATOM 370  O OG  . SER A 1 55   ? 125.456 96.248  124.411 1.00 117.24 ? 55   SER A OG  1 
ATOM 371  N N   . LYS A 1 56   ? 125.832 100.214 123.829 1.00 105.79 ? 56   LYS A N   1 
ATOM 372  C CA  . LYS A 1 56   ? 127.088 100.952 123.784 1.00 119.82 ? 56   LYS A CA  1 
ATOM 373  C C   . LYS A 1 56   ? 128.135 100.215 124.607 1.00 128.68 ? 56   LYS A C   1 
ATOM 374  O O   . LYS A 1 56   ? 129.271 100.033 124.175 1.00 130.68 ? 56   LYS A O   1 
ATOM 375  C CB  . LYS A 1 56   ? 126.994 102.354 124.388 1.00 131.11 ? 56   LYS A CB  1 
ATOM 376  C CG  . LYS A 1 56   ? 125.944 103.283 123.800 1.00 147.22 ? 56   LYS A CG  1 
ATOM 377  C CD  . LYS A 1 56   ? 125.960 104.673 124.389 1.00 157.89 ? 56   LYS A CD  1 
ATOM 378  C CE  . LYS A 1 56   ? 127.321 105.347 124.382 1.00 157.82 ? 56   LYS A CE  1 
ATOM 379  N NZ  . LYS A 1 56   ? 127.858 105.563 123.016 1.00 153.20 ? 56   LYS A NZ  1 
ATOM 380  N N   . THR A 1 57   ? 127.728 99.852  125.828 1.00 149.76 ? 57   THR A N   1 
ATOM 381  C CA  . THR A 1 57   ? 128.552 99.105  126.762 1.00 174.75 ? 57   THR A CA  1 
ATOM 382  C C   . THR A 1 57   ? 127.741 97.883  127.192 1.00 173.52 ? 57   THR A C   1 
ATOM 383  O O   . THR A 1 57   ? 127.343 97.089  126.342 1.00 178.91 ? 57   THR A O   1 
ATOM 384  C CB  . THR A 1 57   ? 129.049 100.028 127.888 1.00 199.31 ? 57   THR A CB  1 
ATOM 385  O OG1 . THR A 1 57   ? 129.783 99.238  128.825 1.00 209.66 ? 57   THR A OG1 1 
ATOM 386  C CG2 . THR A 1 57   ? 127.943 100.785 128.600 1.00 206.91 ? 57   THR A CG2 1 
ATOM 387  N N   . ALA A 1 58   ? 127.499 97.742  128.502 1.00 167.83 ? 58   ALA A N   1 
ATOM 388  C CA  . ALA A 1 58   ? 126.566 96.762  129.026 1.00 168.07 ? 58   ALA A CA  1 
ATOM 389  C C   . ALA A 1 58   ? 125.532 97.485  129.883 1.00 162.52 ? 58   ALA A C   1 
ATOM 390  O O   . ALA A 1 58   ? 125.805 98.571  130.386 1.00 150.13 ? 58   ALA A O   1 
ATOM 391  C CB  . ALA A 1 58   ? 127.323 95.724  129.817 1.00 175.70 ? 58   ALA A CB  1 
ATOM 392  N N   . ASP A 1 59   ? 124.341 96.891  130.018 1.00 178.10 ? 59   ASP A N   1 
ATOM 393  C CA  . ASP A 1 59   ? 123.323 97.397  130.926 1.00 196.46 ? 59   ASP A CA  1 
ATOM 394  C C   . ASP A 1 59   ? 122.486 98.470  130.225 1.00 181.16 ? 59   ASP A C   1 
ATOM 395  O O   . ASP A 1 59   ? 121.563 99.010  130.828 1.00 186.49 ? 59   ASP A O   1 
ATOM 396  C CB  . ASP A 1 59   ? 123.965 97.895  132.232 1.00 231.60 ? 59   ASP A CB  1 
ATOM 397  C CG  . ASP A 1 59   ? 123.031 98.086  133.417 1.00 262.89 ? 59   ASP A CG  1 
ATOM 398  O OD1 . ASP A 1 59   ? 121.806 98.055  133.223 1.00 276.45 ? 59   ASP A OD1 1 
ATOM 399  O OD2 . ASP A 1 59   ? 123.548 98.291  134.536 1.00 279.58 ? 59   ASP A OD2 1 
ATOM 400  N N   . LYS A 1 60   ? 122.781 98.772  128.953 1.00 163.89 ? 60   LYS A N   1 
ATOM 401  C CA  . LYS A 1 60   ? 121.977 99.706  128.176 1.00 153.16 ? 60   LYS A CA  1 
ATOM 402  C C   . LYS A 1 60   ? 121.596 99.041  126.856 1.00 128.24 ? 60   LYS A C   1 
ATOM 403  O O   . LYS A 1 60   ? 122.444 98.440  126.208 1.00 128.16 ? 60   LYS A O   1 
ATOM 404  C CB  . LYS A 1 60   ? 122.749 101.003 127.912 1.00 171.00 ? 60   LYS A CB  1 
ATOM 405  C CG  . LYS A 1 60   ? 123.177 101.792 129.144 1.00 189.20 ? 60   LYS A CG  1 
ATOM 406  C CD  . LYS A 1 60   ? 123.907 103.080 128.812 1.00 209.01 ? 60   LYS A CD  1 
ATOM 407  C CE  . LYS A 1 60   ? 125.215 102.858 128.076 1.00 226.25 ? 60   LYS A CE  1 
ATOM 408  N NZ  . LYS A 1 60   ? 125.930 104.132 127.822 1.00 232.15 ? 60   LYS A NZ  1 
ATOM 409  N N   . ILE A 1 61   ? 120.321 99.147  126.465 1.00 107.75 ? 61   ILE A N   1 
ATOM 410  C CA  . ILE A 1 61   ? 119.858 98.631  125.186 1.00 96.97  ? 61   ILE A CA  1 
ATOM 411  C C   . ILE A 1 61   ? 119.372 99.806  124.336 1.00 104.05 ? 61   ILE A C   1 
ATOM 412  O O   . ILE A 1 61   ? 118.213 100.203 124.450 1.00 114.78 ? 61   ILE A O   1 
ATOM 413  C CB  . ILE A 1 61   ? 118.753 97.575  125.405 1.00 89.62  ? 61   ILE A CB  1 
ATOM 414  C CG1 . ILE A 1 61   ? 119.233 96.418  126.283 1.00 90.90  ? 61   ILE A CG1 1 
ATOM 415  C CG2 . ILE A 1 61   ? 118.202 97.068  124.081 1.00 91.63  ? 61   ILE A CG2 1 
ATOM 416  C CD1 . ILE A 1 61   ? 118.174 95.373  126.548 1.00 92.94  ? 61   ILE A CD1 1 
ATOM 417  N N   . GLU A 1 62   ? 120.240 100.351 123.466 1.00 101.61 ? 62   GLU A N   1 
ATOM 418  C CA  . GLU A 1 62   ? 119.894 101.551 122.713 1.00 102.96 ? 62   GLU A CA  1 
ATOM 419  C C   . GLU A 1 62   ? 118.705 101.284 121.792 1.00 102.80 ? 62   GLU A C   1 
ATOM 420  O O   . GLU A 1 62   ? 117.729 102.030 121.825 1.00 117.01 ? 62   GLU A O   1 
ATOM 421  C CB  . GLU A 1 62   ? 121.071 102.093 121.901 1.00 111.15 ? 62   GLU A CB  1 
ATOM 422  C CG  . GLU A 1 62   ? 122.114 102.784 122.757 1.00 135.51 ? 62   GLU A CG  1 
ATOM 423  C CD  . GLU A 1 62   ? 122.884 101.839 123.661 1.00 154.87 ? 62   GLU A CD  1 
ATOM 424  O OE1 . GLU A 1 62   ? 122.852 102.022 124.901 1.00 169.96 ? 62   GLU A OE1 1 
ATOM 425  O OE2 . GLU A 1 62   ? 123.529 100.932 123.118 1.00 153.42 ? 62   GLU A OE2 1 
ATOM 426  N N   . GLY A 1 63   ? 118.785 100.225 120.979 1.00 95.06  ? 63   GLY A N   1 
ATOM 427  C CA  . GLY A 1 63   ? 117.754 99.940  119.991 1.00 87.29  ? 63   GLY A CA  1 
ATOM 428  C C   . GLY A 1 63   ? 117.493 98.447  119.842 1.00 66.17  ? 63   GLY A C   1 
ATOM 429  O O   . GLY A 1 63   ? 118.360 97.636  120.100 1.00 63.01  ? 63   GLY A O   1 
ATOM 430  N N   . PHE A 1 64   ? 116.296 98.091  119.398 1.00 57.98  ? 64   PHE A N   1 
ATOM 431  C CA  . PHE A 1 64   ? 115.986 96.695  119.176 1.00 62.62  ? 64   PHE A CA  1 
ATOM 432  C C   . PHE A 1 64   ? 115.305 96.556  117.810 1.00 65.52  ? 64   PHE A C   1 
ATOM 433  O O   . PHE A 1 64   ? 114.576 97.442  117.372 1.00 79.00  ? 64   PHE A O   1 
ATOM 434  C CB  . PHE A 1 64   ? 115.245 96.131  120.402 1.00 75.41  ? 64   PHE A CB  1 
ATOM 435  C CG  . PHE A 1 64   ? 113.961 96.813  120.787 1.00 97.67  ? 64   PHE A CG  1 
ATOM 436  C CD1 . PHE A 1 64   ? 112.842 96.735  119.970 1.00 118.27 ? 64   PHE A CD1 1 
ATOM 437  C CD2 . PHE A 1 64   ? 113.865 97.514  121.978 1.00 116.23 ? 64   PHE A CD2 1 
ATOM 438  C CE1 . PHE A 1 64   ? 111.655 97.358  120.328 1.00 129.52 ? 64   PHE A CE1 1 
ATOM 439  C CE2 . PHE A 1 64   ? 112.678 98.140  122.331 1.00 141.08 ? 64   PHE A CE2 1 
ATOM 440  C CZ  . PHE A 1 64   ? 111.576 98.061  121.508 1.00 140.55 ? 64   PHE A CZ  1 
ATOM 441  N N   . LEU A 1 65   ? 115.624 95.465  117.101 1.00 61.65  ? 65   LEU A N   1 
ATOM 442  C CA  . LEU A 1 65   ? 114.830 94.964  115.990 1.00 58.28  ? 65   LEU A CA  1 
ATOM 443  C C   . LEU A 1 65   ? 113.973 93.864  116.576 1.00 48.77  ? 65   LEU A C   1 
ATOM 444  O O   . LEU A 1 65   ? 114.316 93.329  117.612 1.00 49.83  ? 65   LEU A O   1 
ATOM 445  C CB  . LEU A 1 65   ? 115.710 94.346  114.899 1.00 68.29  ? 65   LEU A CB  1 
ATOM 446  C CG  . LEU A 1 65   ? 116.864 95.188  114.350 1.00 88.28  ? 65   LEU A CG  1 
ATOM 447  C CD1 . LEU A 1 65   ? 118.059 95.188  115.284 1.00 95.82  ? 65   LEU A CD1 1 
ATOM 448  C CD2 . LEU A 1 65   ? 117.309 94.689  112.975 1.00 95.39  ? 65   LEU A CD2 1 
ATOM 449  N N   . ASP A 1 66   ? 112.921 93.462  115.898 1.00 54.01  ? 66   ASP A N   1 
ATOM 450  C CA  . ASP A 1 66   ? 112.269 92.247  116.328 1.00 70.06  ? 66   ASP A CA  1 
ATOM 451  C C   . ASP A 1 66   ? 112.444 91.207  115.228 1.00 69.68  ? 66   ASP A C   1 
ATOM 452  O O   . ASP A 1 66   ? 112.061 91.449  114.091 1.00 82.32  ? 66   ASP A O   1 
ATOM 453  C CB  . ASP A 1 66   ? 110.809 92.507  116.696 1.00 94.44  ? 66   ASP A CB  1 
ATOM 454  C CG  . ASP A 1 66   ? 110.135 91.306  117.337 1.00 121.50 ? 66   ASP A CG  1 
ATOM 455  O OD1 . ASP A 1 66   ? 110.788 90.245  117.441 1.00 130.35 ? 66   ASP A OD1 1 
ATOM 456  O OD2 . ASP A 1 66   ? 108.960 91.440  117.727 1.00 138.04 ? 66   ASP A OD2 1 
ATOM 457  N N   . ILE A 1 67   ? 113.015 90.052  115.579 1.00 63.06  ? 67   ILE A N   1 
ATOM 458  C CA  . ILE A 1 67   ? 113.267 89.006  114.607 1.00 60.31  ? 67   ILE A CA  1 
ATOM 459  C C   . ILE A 1 67   ? 111.924 88.573  114.043 1.00 56.07  ? 67   ILE A C   1 
ATOM 460  O O   . ILE A 1 67   ? 111.800 88.366  112.841 1.00 67.74  ? 67   ILE A O   1 
ATOM 461  C CB  . ILE A 1 67   ? 114.062 87.834  115.216 1.00 71.19  ? 67   ILE A CB  1 
ATOM 462  C CG1 . ILE A 1 67   ? 115.401 88.309  115.795 1.00 74.30  ? 67   ILE A CG1 1 
ATOM 463  C CG2 . ILE A 1 67   ? 114.249 86.701  114.205 1.00 83.16  ? 67   ILE A CG2 1 
ATOM 464  C CD1 . ILE A 1 67   ? 116.217 87.200  116.440 1.00 84.08  ? 67   ILE A CD1 1 
ATOM 465  N N   . MET A 1 68   ? 110.906 88.530  114.893 1.00 57.62  ? 68   MET A N   1 
ATOM 466  C CA  . MET A 1 68   ? 109.553 88.310  114.420 1.00 75.29  ? 68   MET A CA  1 
ATOM 467  C C   . MET A 1 68   ? 109.325 89.017  113.086 1.00 71.98  ? 68   MET A C   1 
ATOM 468  O O   . MET A 1 68   ? 108.574 88.509  112.259 1.00 75.11  ? 68   MET A O   1 
ATOM 469  C CB  . MET A 1 68   ? 108.523 88.836  115.423 1.00 100.88 ? 68   MET A CB  1 
ATOM 470  C CG  . MET A 1 68   ? 108.096 87.828  116.489 1.00 118.55 ? 68   MET A CG  1 
ATOM 471  S SD  . MET A 1 68   ? 107.243 86.348  115.854 1.00 147.10 ? 68   MET A SD  1 
ATOM 472  C CE  . MET A 1 68   ? 106.462 86.974  114.365 1.00 145.75 ? 68   MET A CE  1 
ATOM 473  N N   . GLU A 1 69   ? 109.970 90.175  112.874 1.00 71.94  ? 69   GLU A N   1 
ATOM 474  C CA  . GLU A 1 69   ? 109.708 90.984  111.693 1.00 78.72  ? 69   GLU A CA  1 
ATOM 475  C C   . GLU A 1 69   ? 110.981 91.451  110.979 1.00 72.23  ? 69   GLU A C   1 
ATOM 476  O O   . GLU A 1 69   ? 111.123 92.646  110.732 1.00 71.66  ? 69   GLU A O   1 
ATOM 477  C CB  . GLU A 1 69   ? 108.927 92.230  112.109 1.00 106.35 ? 69   GLU A CB  1 
ATOM 478  C CG  . GLU A 1 69   ? 107.627 91.929  112.835 1.00 140.47 ? 69   GLU A CG  1 
ATOM 479  C CD  . GLU A 1 69   ? 106.835 93.154  113.269 1.00 169.04 ? 69   GLU A CD  1 
ATOM 480  O OE1 . GLU A 1 69   ? 105.736 92.972  113.838 1.00 171.70 ? 69   GLU A OE1 1 
ATOM 481  O OE2 . GLU A 1 69   ? 107.318 94.284  113.048 1.00 185.96 ? 69   GLU A OE2 1 
ATOM 482  N N   . ILE A 1 70   ? 111.886 90.528  110.625 1.00 64.61  ? 70   ILE A N   1 
ATOM 483  C CA  . ILE A 1 70   ? 112.996 90.838  109.734 1.00 59.61  ? 70   ILE A CA  1 
ATOM 484  C C   . ILE A 1 70   ? 112.619 90.300  108.356 1.00 66.97  ? 70   ILE A C   1 
ATOM 485  O O   . ILE A 1 70   ? 112.397 89.102  108.216 1.00 78.10  ? 70   ILE A O   1 
ATOM 486  C CB  . ILE A 1 70   ? 114.329 90.261  110.260 1.00 53.14  ? 70   ILE A CB  1 
ATOM 487  C CG1 . ILE A 1 70   ? 114.973 91.200  111.276 1.00 55.02  ? 70   ILE A CG1 1 
ATOM 488  C CG2 . ILE A 1 70   ? 115.307 89.964  109.126 1.00 56.43  ? 70   ILE A CG2 1 
ATOM 489  C CD1 . ILE A 1 70   ? 116.142 90.596  112.017 1.00 63.78  ? 70   ILE A CD1 1 
ATOM 490  N N   . LYS A 1 71   ? 112.517 91.180  107.354 1.00 62.45  ? 71   LYS A N   1 
ATOM 491  C CA  . LYS A 1 71   ? 111.992 90.785  106.059 1.00 62.36  ? 71   LYS A CA  1 
ATOM 492  C C   . LYS A 1 71   ? 113.072 90.121  105.213 1.00 63.65  ? 71   LYS A C   1 
ATOM 493  O O   . LYS A 1 71   ? 112.782 89.143  104.527 1.00 76.72  ? 71   LYS A O   1 
ATOM 494  C CB  . LYS A 1 71   ? 111.390 91.985  105.333 1.00 69.23  ? 71   LYS A CB  1 
ATOM 495  C CG  . LYS A 1 71   ? 110.183 92.606  106.022 1.00 75.68  ? 71   LYS A CG  1 
ATOM 496  C CD  . LYS A 1 71   ? 109.062 91.634  106.305 1.00 79.09  ? 71   LYS A CD  1 
ATOM 497  C CE  . LYS A 1 71   ? 107.850 92.320  106.898 1.00 87.60  ? 71   LYS A CE  1 
ATOM 498  N NZ  . LYS A 1 71   ? 106.799 91.348  107.285 1.00 96.18  ? 71   LYS A NZ  1 
ATOM 499  N N   . GLU A 1 72   ? 114.297 90.650  105.240 1.00 60.24  ? 72   GLU A N   1 
ATOM 500  C CA  . GLU A 1 72   ? 115.392 90.050  104.489 1.00 69.29  ? 72   GLU A CA  1 
ATOM 501  C C   . GLU A 1 72   ? 116.705 90.290  105.219 1.00 64.64  ? 72   GLU A C   1 
ATOM 502  O O   . GLU A 1 72   ? 116.806 91.239  105.985 1.00 73.20  ? 72   GLU A O   1 
ATOM 503  C CB  . GLU A 1 72   ? 115.486 90.637  103.080 1.00 88.63  ? 72   GLU A CB  1 
ATOM 504  C CG  . GLU A 1 72   ? 115.750 92.135  103.071 1.00 111.46 ? 72   GLU A CG  1 
ATOM 505  C CD  . GLU A 1 72   ? 115.898 92.748  101.687 1.00 128.45 ? 72   GLU A CD  1 
ATOM 506  O OE1 . GLU A 1 72   ? 115.856 91.992  100.691 1.00 130.73 ? 72   GLU A OE1 1 
ATOM 507  O OE2 . GLU A 1 72   ? 116.088 93.982  101.608 1.00 129.64 ? 72   GLU A OE2 1 
ATOM 508  N N   . ILE A 1 73   ? 117.700 89.433  104.970 1.00 55.91  ? 73   ILE A N   1 
ATOM 509  C CA  . ILE A 1 73   ? 118.999 89.579  105.598 1.00 55.15  ? 73   ILE A CA  1 
ATOM 510  C C   . ILE A 1 73   ? 120.050 89.492  104.506 1.00 55.78  ? 73   ILE A C   1 
ATOM 511  O O   . ILE A 1 73   ? 120.749 88.493  104.405 1.00 61.77  ? 73   ILE A O   1 
ATOM 512  C CB  . ILE A 1 73   ? 119.230 88.503  106.677 1.00 67.15  ? 73   ILE A CB  1 
ATOM 513  C CG1 . ILE A 1 73   ? 118.002 88.305  107.573 1.00 80.83  ? 73   ILE A CG1 1 
ATOM 514  C CG2 . ILE A 1 73   ? 120.483 88.829  107.485 1.00 73.31  ? 73   ILE A CG2 1 
ATOM 515  C CD1 . ILE A 1 73   ? 118.172 87.217  108.622 1.00 92.31  ? 73   ILE A CD1 1 
ATOM 516  N N   . ARG A 1 74   ? 120.147 90.525  103.673 1.00 61.87  ? 74   ARG A N   1 
ATOM 517  C CA  . ARG A 1 74   ? 120.973 90.401  102.481 1.00 69.36  ? 74   ARG A CA  1 
ATOM 518  C C   . ARG A 1 74   ? 122.460 90.419  102.846 1.00 60.66  ? 74   ARG A C   1 
ATOM 519  O O   . ARG A 1 74   ? 122.886 91.111  103.755 1.00 60.80  ? 74   ARG A O   1 
ATOM 520  C CB  . ARG A 1 74   ? 120.580 91.408  101.397 1.00 83.57  ? 74   ARG A CB  1 
ATOM 521  C CG  . ARG A 1 74   ? 120.474 92.863  101.821 1.00 93.00  ? 74   ARG A CG  1 
ATOM 522  C CD  . ARG A 1 74   ? 119.774 93.500  100.629 1.00 94.02  ? 74   ARG A CD  1 
ATOM 523  N NE  . ARG A 1 74   ? 119.720 94.948  100.571 1.00 98.61  ? 74   ARG A NE  1 
ATOM 524  C CZ  . ARG A 1 74   ? 120.250 95.682  99.598  1.00 118.34 ? 74   ARG A CZ  1 
ATOM 525  N NH1 . ARG A 1 74   ? 121.082 95.146  98.726  1.00 134.04 ? 74   ARG A NH1 1 
ATOM 526  N NH2 . ARG A 1 74   ? 119.961 96.963  99.498  1.00 123.87 ? 74   ARG A NH2 1 
ATOM 527  N N   . PRO A 1 75   ? 123.284 89.584  102.175 1.00 64.56  ? 75   PRO A N   1 
ATOM 528  C CA  . PRO A 1 75   ? 124.668 89.331  102.579 1.00 59.62  ? 75   PRO A CA  1 
ATOM 529  C C   . PRO A 1 75   ? 125.751 90.396  102.487 1.00 53.51  ? 75   PRO A C   1 
ATOM 530  O O   . PRO A 1 75   ? 126.690 90.324  103.261 1.00 57.15  ? 75   PRO A O   1 
ATOM 531  C CB  . PRO A 1 75   ? 125.139 88.264  101.575 1.00 74.32  ? 75   PRO A CB  1 
ATOM 532  C CG  . PRO A 1 75   ? 123.870 87.575  101.154 1.00 84.26  ? 75   PRO A CG  1 
ATOM 533  C CD  . PRO A 1 75   ? 122.885 88.720  101.050 1.00 82.47  ? 75   PRO A CD  1 
ATOM 534  N N   . GLY A 1 76   ? 125.688 91.316  101.521 1.00 59.97  ? 76   GLY A N   1 
ATOM 535  C CA  . GLY A 1 76   ? 126.816 92.198  101.248 1.00 72.97  ? 76   GLY A CA  1 
ATOM 536  C C   . GLY A 1 76   ? 126.554 93.670  101.581 1.00 85.19  ? 76   GLY A C   1 
ATOM 537  O O   . GLY A 1 76   ? 125.488 94.026  102.084 1.00 101.09 ? 76   GLY A O   1 
ATOM 538  N N   . LYS A 1 77   ? 127.541 94.523  101.267 1.00 81.12  ? 77   LYS A N   1 
ATOM 539  C CA  . LYS A 1 77   ? 127.458 95.948  101.550 1.00 81.52  ? 77   LYS A CA  1 
ATOM 540  C C   . LYS A 1 77   ? 126.762 96.669  100.399 1.00 80.40  ? 77   LYS A C   1 
ATOM 541  O O   . LYS A 1 77   ? 127.392 97.432  99.672  1.00 80.53  ? 77   LYS A O   1 
ATOM 542  C CB  . LYS A 1 77   ? 128.849 96.542  101.785 1.00 83.96  ? 77   LYS A CB  1 
ATOM 543  C CG  . LYS A 1 77   ? 129.891 96.187  100.732 1.00 92.92  ? 77   LYS A CG  1 
ATOM 544  C CD  . LYS A 1 77   ? 130.917 97.279  100.497 1.00 105.49 ? 77   LYS A CD  1 
ATOM 545  C CE  . LYS A 1 77   ? 131.764 97.599  101.712 1.00 112.55 ? 77   LYS A CE  1 
ATOM 546  N NZ  . LYS A 1 77   ? 132.679 96.486  102.061 1.00 115.75 ? 77   LYS A NZ  1 
ATOM 547  N N   . ASN A 1 78   ? 125.455 96.446  100.256 1.00 89.20  ? 78   ASN A N   1 
ATOM 548  C CA  . ASN A 1 78   ? 124.769 96.926  99.071  1.00 103.81 ? 78   ASN A CA  1 
ATOM 549  C C   . ASN A 1 78   ? 123.742 98.016  99.382  1.00 114.00 ? 78   ASN A C   1 
ATOM 550  O O   . ASN A 1 78   ? 123.353 98.729  98.458  1.00 128.66 ? 78   ASN A O   1 
ATOM 551  C CB  . ASN A 1 78   ? 124.149 95.779  98.274  1.00 117.89 ? 78   ASN A CB  1 
ATOM 552  C CG  . ASN A 1 78   ? 123.525 96.257  96.978  1.00 144.53 ? 78   ASN A CG  1 
ATOM 553  O OD1 . ASN A 1 78   ? 122.326 96.090  96.758  1.00 158.88 ? 78   ASN A OD1 1 
ATOM 554  N ND2 . ASN A 1 78   ? 124.324 96.877  96.123  1.00 151.64 ? 78   ASN A ND2 1 
ATOM 555  N N   . SER A 1 79   ? 123.300 98.186  100.639 1.00 114.77 ? 79   SER A N   1 
ATOM 556  C CA  . SER A 1 79   ? 122.239 99.155  100.907 1.00 116.90 ? 79   SER A CA  1 
ATOM 557  C C   . SER A 1 79   ? 122.703 100.358 101.726 1.00 114.28 ? 79   SER A C   1 
ATOM 558  O O   . SER A 1 79   ? 123.058 100.201 102.884 1.00 110.88 ? 79   SER A O   1 
ATOM 559  C CB  . SER A 1 79   ? 121.074 98.535  101.611 1.00 111.01 ? 79   SER A CB  1 
ATOM 560  O OG  . SER A 1 79   ? 120.056 99.508  101.793 1.00 107.15 ? 79   SER A OG  1 
ATOM 561  N N   . LYS A 1 80   ? 122.570 101.562 101.153 1.00 112.98 ? 80   LYS A N   1 
ATOM 562  C CA  . LYS A 1 80   ? 122.610 102.794 101.920 1.00 109.69 ? 80   LYS A CA  1 
ATOM 563  C C   . LYS A 1 80   ? 123.850 102.797 102.804 1.00 96.15  ? 80   LYS A C   1 
ATOM 564  O O   . LYS A 1 80   ? 124.946 102.548 102.321 1.00 91.74  ? 80   LYS A O   1 
ATOM 565  C CB  . LYS A 1 80   ? 121.313 102.907 102.725 1.00 125.12 ? 80   LYS A CB  1 
ATOM 566  C CG  . LYS A 1 80   ? 120.041 102.925 101.892 1.00 144.98 ? 80   LYS A CG  1 
ATOM 567  C CD  . LYS A 1 80   ? 119.958 104.101 100.930 1.00 160.71 ? 80   LYS A CD  1 
ATOM 568  C CE  . LYS A 1 80   ? 120.035 105.462 101.596 1.00 164.32 ? 80   LYS A CE  1 
ATOM 569  N NZ  . LYS A 1 80   ? 118.907 105.694 102.531 1.00 165.68 ? 80   LYS A NZ  1 
ATOM 570  N N   . ASP A 1 81   ? 123.664 103.094 104.090 1.00 102.18 ? 81   ASP A N   1 
ATOM 571  C CA  . ASP A 1 81   ? 124.676 102.867 105.105 1.00 124.88 ? 81   ASP A CA  1 
ATOM 572  C C   . ASP A 1 81   ? 126.063 102.720 104.482 1.00 128.86 ? 81   ASP A C   1 
ATOM 573  O O   . ASP A 1 81   ? 126.811 103.691 104.428 1.00 140.97 ? 81   ASP A O   1 
ATOM 574  C CB  . ASP A 1 81   ? 124.306 101.647 105.945 1.00 149.29 ? 81   ASP A CB  1 
ATOM 575  C CG  . ASP A 1 81   ? 122.907 101.725 106.528 1.00 166.45 ? 81   ASP A CG  1 
ATOM 576  O OD1 . ASP A 1 81   ? 121.954 101.880 105.745 1.00 163.00 ? 81   ASP A OD1 1 
ATOM 577  O OD2 . ASP A 1 81   ? 122.783 101.626 107.756 1.00 179.75 ? 81   ASP A OD2 1 
ATOM 578  N N   . PHE A 1 82   ? 126.405 101.512 104.014 1.00 126.22 ? 82   PHE A N   1 
ATOM 579  C CA  . PHE A 1 82   ? 127.761 101.209 103.588 1.00 128.29 ? 82   PHE A CA  1 
ATOM 580  C C   . PHE A 1 82   ? 128.164 102.109 102.419 1.00 145.60 ? 82   PHE A C   1 
ATOM 581  O O   . PHE A 1 82   ? 129.299 102.578 102.373 1.00 145.98 ? 82   PHE A O   1 
ATOM 582  C CB  . PHE A 1 82   ? 127.901 99.720  103.256 1.00 116.41 ? 82   PHE A CB  1 
ATOM 583  C CG  . PHE A 1 82   ? 127.752 98.804  104.443 1.00 107.44 ? 82   PHE A CG  1 
ATOM 584  C CD1 . PHE A 1 82   ? 128.590 98.915  105.545 1.00 107.77 ? 82   PHE A CD1 1 
ATOM 585  C CD2 . PHE A 1 82   ? 126.771 97.826  104.455 1.00 113.18 ? 82   PHE A CD2 1 
ATOM 586  C CE1 . PHE A 1 82   ? 128.441 98.065  106.632 1.00 121.04 ? 82   PHE A CE1 1 
ATOM 587  C CE2 . PHE A 1 82   ? 126.629 96.976  105.543 1.00 126.91 ? 82   PHE A CE2 1 
ATOM 588  C CZ  . PHE A 1 82   ? 127.451 97.106  106.639 1.00 130.14 ? 82   PHE A CZ  1 
ATOM 589  N N   . GLU A 1 83   ? 127.234 102.368 101.490 1.00 164.03 ? 83   GLU A N   1 
ATOM 590  C CA  . GLU A 1 83   ? 127.489 103.296 100.397 1.00 181.85 ? 83   GLU A CA  1 
ATOM 591  C C   . GLU A 1 83   ? 127.850 104.667 100.968 1.00 171.97 ? 83   GLU A C   1 
ATOM 592  O O   . GLU A 1 83   ? 128.777 105.311 100.487 1.00 174.96 ? 83   GLU A O   1 
ATOM 593  C CB  . GLU A 1 83   ? 126.286 103.400 99.457  1.00 202.40 ? 83   GLU A CB  1 
ATOM 594  C CG  . GLU A 1 83   ? 125.928 102.085 98.787  1.00 226.54 ? 83   GLU A CG  1 
ATOM 595  C CD  . GLU A 1 83   ? 124.740 102.138 97.842  1.00 251.82 ? 83   GLU A CD  1 
ATOM 596  O OE1 . GLU A 1 83   ? 124.152 103.228 97.685  1.00 260.71 ? 83   GLU A OE1 1 
ATOM 597  O OE2 . GLU A 1 83   ? 124.403 101.084 97.267  1.00 266.01 ? 83   GLU A OE2 1 
ATOM 598  N N   . ARG A 1 84   ? 127.118 105.101 102.001 1.00 163.89 ? 84   ARG A N   1 
ATOM 599  C CA  . ARG A 1 84   ? 127.390 106.367 102.665 1.00 159.43 ? 84   ARG A CA  1 
ATOM 600  C C   . ARG A 1 84   ? 128.755 106.314 103.349 1.00 136.40 ? 84   ARG A C   1 
ATOM 601  O O   . ARG A 1 84   ? 129.224 105.242 103.716 1.00 121.36 ? 84   ARG A O   1 
ATOM 602  C CB  . ARG A 1 84   ? 126.298 106.670 103.694 1.00 185.15 ? 84   ARG A CB  1 
ATOM 603  C CG  . ARG A 1 84   ? 124.895 106.733 103.108 1.00 211.00 ? 84   ARG A CG  1 
ATOM 604  C CD  . ARG A 1 84   ? 124.727 107.869 102.120 1.00 227.29 ? 84   ARG A CD  1 
ATOM 605  N NE  . ARG A 1 84   ? 125.007 109.161 102.731 1.00 241.51 ? 84   ARG A NE  1 
ATOM 606  C CZ  . ARG A 1 84   ? 125.015 110.317 102.080 1.00 259.94 ? 84   ARG A CZ  1 
ATOM 607  N NH1 . ARG A 1 84   ? 124.753 110.352 100.785 1.00 269.53 ? 84   ARG A NH1 1 
ATOM 608  N NH2 . ARG A 1 84   ? 125.285 111.438 102.727 1.00 263.69 ? 84   ARG A NH2 1 
ATOM 609  N N   . ALA A 1 85   ? 129.392 107.482 103.488 1.00 141.04 ? 85   ALA A N   1 
ATOM 610  C CA  . ALA A 1 85   ? 130.665 107.621 104.182 1.00 150.47 ? 85   ALA A CA  1 
ATOM 611  C C   . ALA A 1 85   ? 131.730 106.711 103.559 1.00 157.11 ? 85   ALA A C   1 
ATOM 612  O O   . ALA A 1 85   ? 131.842 106.637 102.335 1.00 159.22 ? 85   ALA A O   1 
ATOM 613  C CB  . ALA A 1 85   ? 130.458 107.373 105.661 1.00 152.38 ? 85   ALA A CB  1 
ATOM 614  N N   . LYS A 1 86   ? 132.531 106.042 104.404 1.00 171.02 ? 86   LYS A N   1 
ATOM 615  C CA  . LYS A 1 86   ? 133.637 105.207 103.957 1.00 177.53 ? 86   LYS A CA  1 
ATOM 616  C C   . LYS A 1 86   ? 133.542 103.822 104.599 1.00 181.34 ? 86   LYS A C   1 
ATOM 617  O O   . LYS A 1 86   ? 133.330 103.707 105.807 1.00 189.51 ? 86   LYS A O   1 
ATOM 618  C CB  . LYS A 1 86   ? 134.970 105.866 104.327 1.00 180.51 ? 86   LYS A CB  1 
ATOM 619  C CG  . LYS A 1 86   ? 135.183 107.263 103.758 1.00 192.91 ? 86   LYS A CG  1 
ATOM 620  C CD  . LYS A 1 86   ? 136.472 107.927 104.198 1.00 212.66 ? 86   LYS A CD  1 
ATOM 621  C CE  . LYS A 1 86   ? 137.720 107.192 103.752 1.00 224.38 ? 86   LYS A CE  1 
ATOM 622  N NZ  . LYS A 1 86   ? 137.757 106.995 102.283 1.00 227.94 ? 86   LYS A NZ  1 
ATOM 623  N N   . ALA A 1 87   ? 133.721 102.770 103.785 1.00 175.35 ? 87   ALA A N   1 
ATOM 624  C CA  . ALA A 1 87   ? 133.766 101.402 104.282 1.00 170.14 ? 87   ALA A CA  1 
ATOM 625  C C   . ALA A 1 87   ? 135.168 100.820 104.096 1.00 178.98 ? 87   ALA A C   1 
ATOM 626  O O   . ALA A 1 87   ? 135.326 99.617  103.898 1.00 176.43 ? 87   ALA A O   1 
ATOM 627  C CB  . ALA A 1 87   ? 132.727 100.557 103.588 1.00 157.89 ? 87   ALA A CB  1 
ATOM 628  N N   . VAL A 1 88   ? 136.186 101.682 104.199 1.00 185.74 ? 88   VAL A N   1 
ATOM 629  C CA  . VAL A 1 88   ? 137.566 101.277 103.984 1.00 190.70 ? 88   VAL A CA  1 
ATOM 630  C C   . VAL A 1 88   ? 137.861 100.008 104.783 1.00 178.65 ? 88   VAL A C   1 
ATOM 631  O O   . VAL A 1 88   ? 138.476 99.082  104.263 1.00 184.34 ? 88   VAL A O   1 
ATOM 632  C CB  . VAL A 1 88   ? 138.560 102.408 104.328 1.00 205.11 ? 88   VAL A CB  1 
ATOM 633  C CG1 . VAL A 1 88   ? 138.473 103.553 103.328 1.00 212.22 ? 88   VAL A CG1 1 
ATOM 634  C CG2 . VAL A 1 88   ? 138.398 102.930 105.752 1.00 208.61 ? 88   VAL A CG2 1 
ATOM 635  N N   . ARG A 1 89   ? 137.369 99.954  106.025 1.00 170.11 ? 89   ARG A N   1 
ATOM 636  C CA  . ARG A 1 89   ? 137.853 98.992  106.999 1.00 175.99 ? 89   ARG A CA  1 
ATOM 637  C C   . ARG A 1 89   ? 137.416 97.568  106.655 1.00 175.70 ? 89   ARG A C   1 
ATOM 638  O O   . ARG A 1 89   ? 138.175 96.629  106.888 1.00 183.68 ? 89   ARG A O   1 
ATOM 639  C CB  . ARG A 1 89   ? 137.400 99.396  108.406 1.00 187.39 ? 89   ARG A CB  1 
ATOM 640  C CG  . ARG A 1 89   ? 138.217 98.778  109.533 1.00 199.56 ? 89   ARG A CG  1 
ATOM 641  C CD  . ARG A 1 89   ? 139.721 98.950  109.372 1.00 209.45 ? 89   ARG A CD  1 
ATOM 642  N NE  . ARG A 1 89   ? 140.353 97.826  108.682 1.00 215.07 ? 89   ARG A NE  1 
ATOM 643  C CZ  . ARG A 1 89   ? 141.022 97.892  107.532 1.00 216.24 ? 89   ARG A CZ  1 
ATOM 644  N NH1 . ARG A 1 89   ? 141.564 96.797  107.028 1.00 213.86 ? 89   ARG A NH1 1 
ATOM 645  N NH2 . ARG A 1 89   ? 141.146 99.038  106.881 1.00 219.34 ? 89   ARG A NH2 1 
ATOM 646  N N   . GLN A 1 90   ? 136.220 97.400  106.076 1.00 168.66 ? 90   GLN A N   1 
ATOM 647  C CA  . GLN A 1 90   ? 135.581 96.091  106.046 1.00 170.50 ? 90   GLN A CA  1 
ATOM 648  C C   . GLN A 1 90   ? 135.414 95.589  104.612 1.00 150.46 ? 90   GLN A C   1 
ATOM 649  O O   . GLN A 1 90   ? 134.852 96.279  103.766 1.00 151.30 ? 90   GLN A O   1 
ATOM 650  C CB  . GLN A 1 90   ? 134.232 96.117  106.768 1.00 199.22 ? 90   GLN A CB  1 
ATOM 651  C CG  . GLN A 1 90   ? 133.438 97.405  106.584 1.00 222.89 ? 90   GLN A CG  1 
ATOM 652  C CD  . GLN A 1 90   ? 133.817 98.461  107.595 1.00 239.00 ? 90   GLN A CD  1 
ATOM 653  O OE1 . GLN A 1 90   ? 133.701 98.260  108.801 1.00 245.61 ? 90   GLN A OE1 1 
ATOM 654  N NE2 . GLN A 1 90   ? 134.278 99.601  107.108 1.00 240.56 ? 90   GLN A NE2 1 
ATOM 655  N N   . LYS A 1 91   ? 135.881 94.356  104.368 1.00 140.85 ? 91   LYS A N   1 
ATOM 656  C CA  . LYS A 1 91   ? 135.732 93.705  103.076 1.00 135.98 ? 91   LYS A CA  1 
ATOM 657  C C   . LYS A 1 91   ? 134.284 93.264  102.895 1.00 120.28 ? 91   LYS A C   1 
ATOM 658  O O   . LYS A 1 91   ? 133.587 93.018  103.872 1.00 111.80 ? 91   LYS A O   1 
ATOM 659  C CB  . LYS A 1 91   ? 136.665 92.497  102.951 1.00 147.57 ? 91   LYS A CB  1 
ATOM 660  C CG  . LYS A 1 91   ? 136.308 91.298  103.822 1.00 162.33 ? 91   LYS A CG  1 
ATOM 661  C CD  . LYS A 1 91   ? 137.144 90.064  103.540 1.00 172.65 ? 91   LYS A CD  1 
ATOM 662  C CE  . LYS A 1 91   ? 138.636 90.331  103.503 1.00 178.24 ? 91   LYS A CE  1 
ATOM 663  N NZ  . LYS A 1 91   ? 139.110 91.037  104.717 1.00 180.97 ? 91   LYS A NZ  1 
ATOM 664  N N   . GLU A 1 92   ? 133.876 93.127  101.628 1.00 133.06 ? 92   GLU A N   1 
ATOM 665  C CA  . GLU A 1 92   ? 132.488 92.933  101.240 1.00 154.44 ? 92   GLU A CA  1 
ATOM 666  C C   . GLU A 1 92   ? 131.858 91.745  101.962 1.00 154.06 ? 92   GLU A C   1 
ATOM 667  O O   . GLU A 1 92   ? 130.713 91.829  102.396 1.00 163.94 ? 92   GLU A O   1 
ATOM 668  C CB  . GLU A 1 92   ? 132.398 92.734  99.724  1.00 185.31 ? 92   GLU A CB  1 
ATOM 669  C CG  . GLU A 1 92   ? 131.040 92.257  99.222  1.00 210.92 ? 92   GLU A CG  1 
ATOM 670  C CD  . GLU A 1 92   ? 130.931 90.775  98.892  1.00 228.80 ? 92   GLU A CD  1 
ATOM 671  O OE1 . GLU A 1 92   ? 130.724 90.454  97.702  1.00 238.29 ? 92   GLU A OE1 1 
ATOM 672  O OE2 . GLU A 1 92   ? 131.040 89.942  99.812  1.00 230.78 ? 92   GLU A OE2 1 
ATOM 673  N N   . ASP A 1 93   ? 132.580 90.625  102.038 1.00 150.59 ? 93   ASP A N   1 
ATOM 674  C CA  . ASP A 1 93   ? 131.986 89.399  102.542 1.00 154.60 ? 93   ASP A CA  1 
ATOM 675  C C   . ASP A 1 93   ? 131.575 89.585  104.001 1.00 136.69 ? 93   ASP A C   1 
ATOM 676  O O   . ASP A 1 93   ? 130.546 89.059  104.417 1.00 142.66 ? 93   ASP A O   1 
ATOM 677  C CB  . ASP A 1 93   ? 132.918 88.201  102.349 1.00 175.44 ? 93   ASP A CB  1 
ATOM 678  C CG  . ASP A 1 93   ? 132.181 86.871  102.290 1.00 191.60 ? 93   ASP A CG  1 
ATOM 679  O OD1 . ASP A 1 93   ? 130.952 86.866  102.520 1.00 185.85 ? 93   ASP A OD1 1 
ATOM 680  O OD2 . ASP A 1 93   ? 132.838 85.853  101.994 1.00 205.78 ? 93   ASP A OD2 1 
ATOM 681  N N   . CYS A 1 94   ? 132.352 90.373  104.754 1.00 110.04 ? 94   CYS A N   1 
ATOM 682  C CA  . CYS A 1 94   ? 132.152 90.514  106.189 1.00 98.83  ? 94   CYS A CA  1 
ATOM 683  C C   . CYS A 1 94   ? 130.823 91.188  106.537 1.00 79.87  ? 94   CYS A C   1 
ATOM 684  O O   . CYS A 1 94   ? 130.150 90.769  107.471 1.00 83.26  ? 94   CYS A O   1 
ATOM 685  C CB  . CYS A 1 94   ? 133.304 91.281  106.823 1.00 110.15 ? 94   CYS A CB  1 
ATOM 686  S SG  . CYS A 1 94   ? 134.801 90.275  107.017 1.00 140.71 ? 94   CYS A SG  1 
ATOM 687  N N   . CYS A 1 95   ? 130.436 92.214  105.781 1.00 70.35  ? 95   CYS A N   1 
ATOM 688  C CA  . CYS A 1 95   ? 129.275 93.023  106.115 1.00 70.23  ? 95   CYS A CA  1 
ATOM 689  C C   . CYS A 1 95   ? 127.976 92.252  105.942 1.00 55.93  ? 95   CYS A C   1 
ATOM 690  O O   . CYS A 1 95   ? 127.842 91.489  105.002 1.00 63.30  ? 95   CYS A O   1 
ATOM 691  C CB  . CYS A 1 95   ? 129.165 94.234  105.200 1.00 93.44  ? 95   CYS A CB  1 
ATOM 692  S SG  . CYS A 1 95   ? 130.679 95.226  105.115 1.00 128.49 ? 95   CYS A SG  1 
ATOM 693  N N   . PHE A 1 96   ? 127.008 92.506  106.822 1.00 49.65  ? 96   PHE A N   1 
ATOM 694  C CA  . PHE A 1 96   ? 125.673 91.950  106.684 1.00 55.04  ? 96   PHE A CA  1 
ATOM 695  C C   . PHE A 1 96   ? 124.656 93.003  107.093 1.00 56.45  ? 96   PHE A C   1 
ATOM 696  O O   . PHE A 1 96   ? 124.701 93.466  108.224 1.00 69.44  ? 96   PHE A O   1 
ATOM 697  C CB  . PHE A 1 96   ? 125.488 90.675  107.515 1.00 67.39  ? 96   PHE A CB  1 
ATOM 698  C CG  . PHE A 1 96   ? 125.624 90.825  109.009 1.00 88.29  ? 96   PHE A CG  1 
ATOM 699  C CD1 . PHE A 1 96   ? 126.813 91.261  109.584 1.00 108.44 ? 96   PHE A CD1 1 
ATOM 700  C CD2 . PHE A 1 96   ? 124.573 90.487  109.848 1.00 101.98 ? 96   PHE A CD2 1 
ATOM 701  C CE1 . PHE A 1 96   ? 126.939 91.386  110.959 1.00 128.75 ? 96   PHE A CE1 1 
ATOM 702  C CE2 . PHE A 1 96   ? 124.698 90.609  111.223 1.00 126.64 ? 96   PHE A CE2 1 
ATOM 703  C CZ  . PHE A 1 96   ? 125.875 91.068  111.772 1.00 139.06 ? 96   PHE A CZ  1 
ATOM 704  N N   . THR A 1 97   ? 123.756 93.388  106.180 1.00 54.39  ? 97   THR A N   1 
ATOM 705  C CA  . THR A 1 97   ? 122.718 94.362  106.482 1.00 51.42  ? 97   THR A CA  1 
ATOM 706  C C   . THR A 1 97   ? 121.373 93.663  106.636 1.00 45.40  ? 97   THR A C   1 
ATOM 707  O O   . THR A 1 97   ? 121.012 92.829  105.815 1.00 50.03  ? 97   THR A O   1 
ATOM 708  C CB  . THR A 1 97   ? 122.623 95.435  105.395 1.00 63.65  ? 97   THR A CB  1 
ATOM 709  O OG1 . THR A 1 97   ? 123.893 96.081  105.317 1.00 69.11  ? 97   THR A OG1 1 
ATOM 710  C CG2 . THR A 1 97   ? 121.539 96.459  105.662 1.00 69.10  ? 97   THR A CG2 1 
ATOM 711  N N   . ILE A 1 98   ? 120.654 94.006  107.705 1.00 43.96  ? 98   ILE A N   1 
ATOM 712  C CA  . ILE A 1 98   ? 119.380 93.393  108.034 1.00 48.85  ? 98   ILE A CA  1 
ATOM 713  C C   . ILE A 1 98   ? 118.310 94.453  107.849 1.00 47.77  ? 98   ILE A C   1 
ATOM 714  O O   . ILE A 1 98   ? 118.504 95.572  108.293 1.00 49.50  ? 98   ILE A O   1 
ATOM 715  C CB  . ILE A 1 98   ? 119.361 92.867  109.483 1.00 60.30  ? 98   ILE A CB  1 
ATOM 716  C CG1 . ILE A 1 98   ? 120.697 92.252  109.905 1.00 74.94  ? 98   ILE A CG1 1 
ATOM 717  C CG2 . ILE A 1 98   ? 118.205 91.895  109.697 1.00 60.33  ? 98   ILE A CG2 1 
ATOM 718  C CD1 . ILE A 1 98   ? 120.893 92.199  111.411 1.00 84.51  ? 98   ILE A CD1 1 
ATOM 719  N N   . LEU A 1 99   ? 117.192 94.082  107.216 1.00 52.11  ? 99   LEU A N   1 
ATOM 720  C CA  . LEU A 1 99   ? 116.099 95.009  106.976 1.00 58.36  ? 99   LEU A CA  1 
ATOM 721  C C   . LEU A 1 99   ? 114.867 94.563  107.761 1.00 57.18  ? 99   LEU A C   1 
ATOM 722  O O   . LEU A 1 99   ? 114.296 93.514  107.487 1.00 61.29  ? 99   LEU A O   1 
ATOM 723  C CB  . LEU A 1 99   ? 115.820 95.087  105.473 1.00 64.57  ? 99   LEU A CB  1 
ATOM 724  C CG  . LEU A 1 99   ? 116.950 95.696  104.646 1.00 73.30  ? 99   LEU A CG  1 
ATOM 725  C CD1 . LEU A 1 99   ? 118.034 94.658  104.340 1.00 75.40  ? 99   LEU A CD1 1 
ATOM 726  C CD2 . LEU A 1 99   ? 116.406 96.342  103.371 1.00 77.73  ? 99   LEU A CD2 1 
ATOM 727  N N   . TYR A 1 100  ? 114.466 95.405  108.724 1.00 49.94  ? 100  TYR A N   1 
ATOM 728  C CA  . TYR A 1 100  ? 113.388 95.134  109.658 1.00 44.30  ? 100  TYR A CA  1 
ATOM 729  C C   . TYR A 1 100  ? 112.369 96.238  109.550 1.00 45.29  ? 100  TYR A C   1 
ATOM 730  O O   . TYR A 1 100  ? 112.753 97.397  109.654 1.00 46.25  ? 100  TYR A O   1 
ATOM 731  C CB  . TYR A 1 100  ? 113.857 95.190  111.111 1.00 47.34  ? 100  TYR A CB  1 
ATOM 732  C CG  . TYR A 1 100  ? 114.513 96.468  111.573 1.00 47.91  ? 100  TYR A CG  1 
ATOM 733  C CD1 . TYR A 1 100  ? 115.705 96.907  111.029 1.00 50.36  ? 100  TYR A CD1 1 
ATOM 734  C CD2 . TYR A 1 100  ? 113.979 97.210  112.610 1.00 54.19  ? 100  TYR A CD2 1 
ATOM 735  C CE1 . TYR A 1 100  ? 116.334 98.056  111.474 1.00 57.45  ? 100  TYR A CE1 1 
ATOM 736  C CE2 . TYR A 1 100  ? 114.597 98.359  113.076 1.00 61.92  ? 100  TYR A CE2 1 
ATOM 737  C CZ  . TYR A 1 100  ? 115.784 98.788  112.507 1.00 63.68  ? 100  TYR A CZ  1 
ATOM 738  O OH  . TYR A 1 100  ? 116.410 99.938  112.944 1.00 69.35  ? 100  TYR A OH  1 
ATOM 739  N N   . GLY A 1 101  ? 111.087 95.894  109.395 1.00 53.02  ? 101  GLY A N   1 
ATOM 740  C CA  . GLY A 1 101  ? 110.085 96.948  109.397 1.00 61.30  ? 101  GLY A CA  1 
ATOM 741  C C   . GLY A 1 101  ? 108.652 96.459  109.261 1.00 56.41  ? 101  GLY A C   1 
ATOM 742  O O   . GLY A 1 101  ? 108.389 95.336  108.842 1.00 57.40  ? 101  GLY A O   1 
ATOM 743  N N   . THR A 1 102  ? 107.744 97.357  109.630 1.00 58.50  ? 102  THR A N   1 
ATOM 744  C CA  . THR A 1 102  ? 106.323 97.117  109.503 1.00 69.83  ? 102  THR A CA  1 
ATOM 745  C C   . THR A 1 102  ? 105.755 98.028  108.419 1.00 67.15  ? 102  THR A C   1 
ATOM 746  O O   . THR A 1 102  ? 104.559 97.986  108.160 1.00 63.23  ? 102  THR A O   1 
ATOM 747  C CB  . THR A 1 102  ? 105.630 97.362  110.851 1.00 93.51  ? 102  THR A CB  1 
ATOM 748  O OG1 . THR A 1 102  ? 106.637 97.655  111.823 1.00 99.81  ? 102  THR A OG1 1 
ATOM 749  C CG2 . THR A 1 102  ? 104.782 96.191  111.306 1.00 106.35 ? 102  THR A CG2 1 
ATOM 750  N N   . GLN A 1 103  ? 106.600 98.860  107.796 1.00 71.85  ? 103  GLN A N   1 
ATOM 751  C CA  . GLN A 1 103  ? 106.114 99.876  106.869 1.00 75.73  ? 103  GLN A CA  1 
ATOM 752  C C   . GLN A 1 103  ? 106.653 99.592  105.470 1.00 74.99  ? 103  GLN A C   1 
ATOM 753  O O   . GLN A 1 103  ? 107.194 98.516  105.252 1.00 88.27  ? 103  GLN A O   1 
ATOM 754  C CB  . GLN A 1 103  ? 106.512 101.264 107.366 1.00 78.73  ? 103  GLN A CB  1 
ATOM 755  C CG  . GLN A 1 103  ? 105.904 101.620 108.712 1.00 85.58  ? 103  GLN A CG  1 
ATOM 756  C CD  . GLN A 1 103  ? 106.554 102.851 109.294 1.00 108.85 ? 103  GLN A CD  1 
ATOM 757  O OE1 . GLN A 1 103  ? 107.618 103.280 108.850 1.00 116.45 ? 103  GLN A OE1 1 
ATOM 758  N NE2 . GLN A 1 103  ? 105.925 103.421 110.311 1.00 127.29 ? 103  GLN A NE2 1 
ATOM 759  N N   . PHE A 1 104  ? 106.480 100.529 104.524 1.00 62.18  ? 104  PHE A N   1 
ATOM 760  C CA  . PHE A 1 104  ? 107.012 100.348 103.183 1.00 53.91  ? 104  PHE A CA  1 
ATOM 761  C C   . PHE A 1 104  ? 108.501 100.668 103.188 1.00 39.07  ? 104  PHE A C   1 
ATOM 762  O O   . PHE A 1 104  ? 109.335 99.800  102.981 1.00 38.37  ? 104  PHE A O   1 
ATOM 763  C CB  . PHE A 1 104  ? 106.257 101.189 102.149 1.00 62.93  ? 104  PHE A CB  1 
ATOM 764  C CG  . PHE A 1 104  ? 106.689 100.953 100.722 1.00 58.53  ? 104  PHE A CG  1 
ATOM 765  C CD1 . PHE A 1 104  ? 107.950 101.340 100.300 1.00 60.43  ? 104  PHE A CD1 1 
ATOM 766  C CD2 . PHE A 1 104  ? 105.829 100.367 99.804  1.00 53.35  ? 104  PHE A CD2 1 
ATOM 767  C CE1 . PHE A 1 104  ? 108.348 101.125 98.993  1.00 68.29  ? 104  PHE A CE1 1 
ATOM 768  C CE2 . PHE A 1 104  ? 106.238 100.124 98.508  1.00 57.60  ? 104  PHE A CE2 1 
ATOM 769  C CZ  . PHE A 1 104  ? 107.494 100.514 98.102  1.00 70.73  ? 104  PHE A CZ  1 
ATOM 770  N N   . VAL A 1 105  ? 108.861 101.914 103.415 1.00 38.79  ? 105  VAL A N   1 
ATOM 771  C CA  . VAL A 1 105  ? 110.269 102.134 103.627 1.00 50.88  ? 105  VAL A CA  1 
ATOM 772  C C   . VAL A 1 105  ? 110.620 101.128 104.714 1.00 53.67  ? 105  VAL A C   1 
ATOM 773  O O   . VAL A 1 105  ? 109.859 100.969 105.672 1.00 63.57  ? 105  VAL A O   1 
ATOM 774  C CB  . VAL A 1 105  ? 110.600 103.588 104.019 1.00 76.79  ? 105  VAL A CB  1 
ATOM 775  C CG1 . VAL A 1 105  ? 112.104 103.852 104.032 1.00 85.84  ? 105  VAL A CG1 1 
ATOM 776  C CG2 . VAL A 1 105  ? 109.893 104.582 103.104 1.00 87.85  ? 105  VAL A CG2 1 
ATOM 777  N N   . LEU A 1 106  ? 111.682 100.345 104.498 1.00 52.08  ? 106  LEU A N   1 
ATOM 778  C CA  . LEU A 1 106  ? 112.155 99.413  105.508 1.00 47.41  ? 106  LEU A CA  1 
ATOM 779  C C   . LEU A 1 106  ? 113.418 99.990  106.129 1.00 47.74  ? 106  LEU A C   1 
ATOM 780  O O   . LEU A 1 106  ? 114.349 100.372 105.424 1.00 51.09  ? 106  LEU A O   1 
ATOM 781  C CB  . LEU A 1 106  ? 112.428 98.045  104.880 1.00 50.25  ? 106  LEU A CB  1 
ATOM 782  C CG  . LEU A 1 106  ? 111.233 97.323  104.254 1.00 55.95  ? 106  LEU A CG  1 
ATOM 783  C CD1 . LEU A 1 106  ? 111.574 95.879  103.930 1.00 58.48  ? 106  LEU A CD1 1 
ATOM 784  C CD2 . LEU A 1 106  ? 110.023 97.380  105.163 1.00 58.73  ? 106  LEU A CD2 1 
ATOM 785  N N   . SER A 1 107  ? 113.412 100.073 107.459 1.00 52.30  ? 107  SER A N   1 
ATOM 786  C CA  . SER A 1 107  ? 114.550 100.545 108.232 1.00 58.05  ? 107  SER A CA  1 
ATOM 787  C C   . SER A 1 107  ? 115.670 99.521  108.182 1.00 52.30  ? 107  SER A C   1 
ATOM 788  O O   . SER A 1 107  ? 115.400 98.330  108.250 1.00 51.40  ? 107  SER A O   1 
ATOM 789  C CB  . SER A 1 107  ? 114.148 100.758 109.656 1.00 67.91  ? 107  SER A CB  1 
ATOM 790  O OG  . SER A 1 107  ? 113.841 99.507  110.258 1.00 66.84  ? 107  SER A OG  1 
ATOM 791  N N   . THR A 1 108  ? 116.910 100.001 108.137 1.00 58.20  ? 108  THR A N   1 
ATOM 792  C CA  . THR A 1 108  ? 118.054 99.134  107.919 1.00 73.17  ? 108  THR A CA  1 
ATOM 793  C C   . THR A 1 108  ? 119.045 99.264  109.069 1.00 73.14  ? 108  THR A C   1 
ATOM 794  O O   . THR A 1 108  ? 119.479 100.364 109.399 1.00 86.79  ? 108  THR A O   1 
ATOM 795  C CB  . THR A 1 108  ? 118.775 99.477  106.610 1.00 93.69  ? 108  THR A CB  1 
ATOM 796  O OG1 . THR A 1 108  ? 119.299 100.798 106.758 1.00 100.05 ? 108  THR A OG1 1 
ATOM 797  C CG2 . THR A 1 108  ? 117.877 99.403  105.393 1.00 100.32 ? 108  THR A CG2 1 
ATOM 798  N N   . LEU A 1 109  ? 119.392 98.121  109.658 1.00 68.33  ? 109  LEU A N   1 
ATOM 799  C CA  . LEU A 1 109  ? 120.539 98.012  110.537 1.00 69.08  ? 109  LEU A CA  1 
ATOM 800  C C   . LEU A 1 109  ? 121.679 97.400  109.745 1.00 71.52  ? 109  LEU A C   1 
ATOM 801  O O   . LEU A 1 109  ? 121.538 96.267  109.303 1.00 81.87  ? 109  LEU A O   1 
ATOM 802  C CB  . LEU A 1 109  ? 120.177 97.094  111.703 1.00 76.21  ? 109  LEU A CB  1 
ATOM 803  C CG  . LEU A 1 109  ? 121.345 96.738  112.620 1.00 88.57  ? 109  LEU A CG  1 
ATOM 804  C CD1 . LEU A 1 109  ? 121.616 97.857  113.616 1.00 98.86  ? 109  LEU A CD1 1 
ATOM 805  C CD2 . LEU A 1 109  ? 121.092 95.421  113.333 1.00 91.42  ? 109  LEU A CD2 1 
ATOM 806  N N   . SER A 1 110  ? 122.787 98.127  109.581 1.00 72.64  ? 110  SER A N   1 
ATOM 807  C CA  . SER A 1 110  ? 123.909 97.609  108.815 1.00 76.09  ? 110  SER A CA  1 
ATOM 808  C C   . SER A 1 110  ? 125.123 97.428  109.719 1.00 79.98  ? 110  SER A C   1 
ATOM 809  O O   . SER A 1 110  ? 125.620 98.397  110.280 1.00 87.31  ? 110  SER A O   1 
ATOM 810  C CB  . SER A 1 110  ? 124.229 98.507  107.679 1.00 76.36  ? 110  SER A CB  1 
ATOM 811  O OG  . SER A 1 110  ? 124.640 99.762  108.175 1.00 81.79  ? 110  SER A OG  1 
ATOM 812  N N   . LEU A 1 111  ? 125.592 96.180  109.822 1.00 71.45  ? 111  LEU A N   1 
ATOM 813  C CA  . LEU A 1 111  ? 126.613 95.778  110.772 1.00 64.50  ? 111  LEU A CA  1 
ATOM 814  C C   . LEU A 1 111  ? 127.789 95.223  109.992 1.00 66.09  ? 111  LEU A C   1 
ATOM 815  O O   . LEU A 1 111  ? 127.591 94.347  109.166 1.00 79.80  ? 111  LEU A O   1 
ATOM 816  C CB  . LEU A 1 111  ? 126.032 94.679  111.663 1.00 69.06  ? 111  LEU A CB  1 
ATOM 817  C CG  . LEU A 1 111  ? 124.652 94.966  112.251 1.00 84.72  ? 111  LEU A CG  1 
ATOM 818  C CD1 . LEU A 1 111  ? 124.066 93.721  112.910 1.00 87.69  ? 111  LEU A CD1 1 
ATOM 819  C CD2 . LEU A 1 111  ? 124.731 96.118  113.244 1.00 90.90  ? 111  LEU A CD2 1 
ATOM 820  N N   . ALA A 1 112  ? 128.997 95.726  110.252 1.00 72.14  ? 112  ALA A N   1 
ATOM 821  C CA  . ALA A 1 112  ? 130.196 95.149  109.665 1.00 81.21  ? 112  ALA A CA  1 
ATOM 822  C C   . ALA A 1 112  ? 131.010 94.465  110.755 1.00 82.18  ? 112  ALA A C   1 
ATOM 823  O O   . ALA A 1 112  ? 131.604 95.139  111.590 1.00 81.75  ? 112  ALA A O   1 
ATOM 824  C CB  . ALA A 1 112  ? 131.000 96.216  108.976 1.00 85.61  ? 112  ALA A CB  1 
ATOM 825  N N   . ALA A 1 113  ? 131.008 93.129  110.745 1.00 87.69  ? 113  ALA A N   1 
ATOM 826  C CA  . ALA A 1 113  ? 131.796 92.352  111.683 1.00 96.67  ? 113  ALA A CA  1 
ATOM 827  C C   . ALA A 1 113  ? 133.262 92.742  111.527 1.00 106.36 ? 113  ALA A C   1 
ATOM 828  O O   . ALA A 1 113  ? 133.705 93.088  110.434 1.00 115.20 ? 113  ALA A O   1 
ATOM 829  C CB  . ALA A 1 113  ? 131.584 90.877  111.442 1.00 96.07  ? 113  ALA A CB  1 
ATOM 830  N N   . ASP A 1 114  ? 133.995 92.721  112.639 1.00 112.30 ? 114  ASP A N   1 
ATOM 831  C CA  . ASP A 1 114  ? 135.429 92.940  112.604 1.00 125.82 ? 114  ASP A CA  1 
ATOM 832  C C   . ASP A 1 114  ? 136.079 91.865  111.737 1.00 123.26 ? 114  ASP A C   1 
ATOM 833  O O   . ASP A 1 114  ? 136.971 92.173  110.952 1.00 128.28 ? 114  ASP A O   1 
ATOM 834  C CB  . ASP A 1 114  ? 136.014 92.964  114.017 1.00 150.58 ? 114  ASP A CB  1 
ATOM 835  C CG  . ASP A 1 114  ? 135.264 92.072  114.990 1.00 173.58 ? 114  ASP A CG  1 
ATOM 836  O OD1 . ASP A 1 114  ? 134.914 90.942  114.593 1.00 181.11 ? 114  ASP A OD1 1 
ATOM 837  O OD2 . ASP A 1 114  ? 135.020 92.520  116.129 1.00 188.50 ? 114  ASP A OD2 1 
ATOM 838  N N   . SER A 1 115  ? 135.608 90.617  111.869 1.00 130.30 ? 115  SER A N   1 
ATOM 839  C CA  . SER A 1 115  ? 136.255 89.478  111.233 1.00 143.56 ? 115  SER A CA  1 
ATOM 840  C C   . SER A 1 115  ? 135.238 88.541  110.582 1.00 129.88 ? 115  SER A C   1 
ATOM 841  O O   . SER A 1 115  ? 134.078 88.484  110.983 1.00 127.06 ? 115  SER A O   1 
ATOM 842  C CB  . SER A 1 115  ? 137.118 88.740  112.226 1.00 166.27 ? 115  SER A CB  1 
ATOM 843  O OG  . SER A 1 115  ? 136.359 88.327  113.354 1.00 176.58 ? 115  SER A OG  1 
ATOM 844  N N   . LYS A 1 116  ? 135.736 87.764  109.611 1.00 124.04 ? 116  LYS A N   1 
ATOM 845  C CA  . LYS A 1 116  ? 134.938 86.994  108.669 1.00 125.87 ? 116  LYS A CA  1 
ATOM 846  C C   . LYS A 1 116  ? 134.075 85.944  109.363 1.00 131.34 ? 116  LYS A C   1 
ATOM 847  O O   . LYS A 1 116  ? 132.910 85.775  109.008 1.00 140.62 ? 116  LYS A O   1 
ATOM 848  C CB  . LYS A 1 116  ? 135.877 86.310  107.669 1.00 129.57 ? 116  LYS A CB  1 
ATOM 849  C CG  . LYS A 1 116  ? 135.267 85.202  106.820 1.00 132.61 ? 116  LYS A CG  1 
ATOM 850  C CD  . LYS A 1 116  ? 134.067 85.628  105.998 1.00 133.64 ? 116  LYS A CD  1 
ATOM 851  C CE  . LYS A 1 116  ? 133.751 84.669  104.869 1.00 137.09 ? 116  LYS A CE  1 
ATOM 852  N NZ  . LYS A 1 116  ? 133.705 83.258  105.323 1.00 137.91 ? 116  LYS A NZ  1 
ATOM 853  N N   . GLU A 1 117  ? 134.663 85.205  110.306 1.00 141.02 ? 117  GLU A N   1 
ATOM 854  C CA  . GLU A 1 117  ? 134.043 83.997  110.832 1.00 158.71 ? 117  GLU A CA  1 
ATOM 855  C C   . GLU A 1 117  ? 132.667 84.331  111.409 1.00 143.94 ? 117  GLU A C   1 
ATOM 856  O O   . GLU A 1 117  ? 131.682 83.653  111.125 1.00 133.66 ? 117  GLU A O   1 
ATOM 857  C CB  . GLU A 1 117  ? 134.962 83.354  111.876 1.00 194.27 ? 117  GLU A CB  1 
ATOM 858  C CG  . GLU A 1 117  ? 134.764 81.855  112.039 1.00 224.87 ? 117  GLU A CG  1 
ATOM 859  C CD  . GLU A 1 117  ? 135.700 81.191  113.036 1.00 253.87 ? 117  GLU A CD  1 
ATOM 860  O OE1 . GLU A 1 117  ? 135.598 79.959  113.207 1.00 268.88 ? 117  GLU A OE1 1 
ATOM 861  O OE2 . GLU A 1 117  ? 136.529 81.904  113.639 1.00 266.27 ? 117  GLU A OE2 1 
ATOM 862  N N   . ASP A 1 118  ? 132.611 85.403  112.203 1.00 139.47 ? 118  ASP A N   1 
ATOM 863  C CA  . ASP A 1 118  ? 131.410 85.770  112.933 1.00 134.30 ? 118  ASP A CA  1 
ATOM 864  C C   . ASP A 1 118  ? 130.271 85.984  111.943 1.00 102.80 ? 118  ASP A C   1 
ATOM 865  O O   . ASP A 1 118  ? 129.185 85.433  112.105 1.00 82.72  ? 118  ASP A O   1 
ATOM 866  C CB  . ASP A 1 118  ? 131.655 87.025  113.773 1.00 153.01 ? 118  ASP A CB  1 
ATOM 867  C CG  . ASP A 1 118  ? 133.072 87.094  114.318 1.00 170.74 ? 118  ASP A CG  1 
ATOM 868  O OD1 . ASP A 1 118  ? 134.006 87.065  113.496 1.00 173.09 ? 118  ASP A OD1 1 
ATOM 869  O OD2 . ASP A 1 118  ? 133.230 87.152  115.552 1.00 184.35 ? 118  ASP A OD2 1 
ATOM 870  N N   . ALA A 1 119  ? 130.552 86.776  110.907 1.00 94.59  ? 119  ALA A N   1 
ATOM 871  C CA  . ALA A 1 119  ? 129.543 87.147  109.934 1.00 94.05  ? 119  ALA A CA  1 
ATOM 872  C C   . ALA A 1 119  ? 128.849 85.892  109.426 1.00 85.34  ? 119  ALA A C   1 
ATOM 873  O O   . ALA A 1 119  ? 127.624 85.823  109.419 1.00 93.52  ? 119  ALA A O   1 
ATOM 874  C CB  . ALA A 1 119  ? 130.163 87.936  108.808 1.00 100.07 ? 119  ALA A CB  1 
ATOM 875  N N   . VAL A 1 120  ? 129.634 84.893  109.023 1.00 84.74  ? 120  VAL A N   1 
ATOM 876  C CA  . VAL A 1 120  ? 129.030 83.656  108.570 1.00 99.52  ? 120  VAL A CA  1 
ATOM 877  C C   . VAL A 1 120  ? 128.058 83.203  109.652 1.00 101.19 ? 120  VAL A C   1 
ATOM 878  O O   . VAL A 1 120  ? 126.908 82.897  109.347 1.00 98.30  ? 120  VAL A O   1 
ATOM 879  C CB  . VAL A 1 120  ? 130.066 82.567  108.236 1.00 124.72 ? 120  VAL A CB  1 
ATOM 880  C CG1 . VAL A 1 120  ? 129.399 81.241  107.879 1.00 129.30 ? 120  VAL A CG1 1 
ATOM 881  C CG2 . VAL A 1 120  ? 131.004 83.017  107.125 1.00 137.94 ? 120  VAL A CG2 1 
ATOM 882  N N   . ASN A 1 121  ? 128.507 83.215  110.915 1.00 106.38 ? 121  ASN A N   1 
ATOM 883  C CA  . ASN A 1 121  ? 127.662 82.754  112.003 1.00 109.43 ? 121  ASN A CA  1 
ATOM 884  C C   . ASN A 1 121  ? 126.368 83.556  111.987 1.00 101.37 ? 121  ASN A C   1 
ATOM 885  O O   . ASN A 1 121  ? 125.290 82.983  111.850 1.00 93.19  ? 121  ASN A O   1 
ATOM 886  C CB  . ASN A 1 121  ? 128.345 82.812  113.372 1.00 114.36 ? 121  ASN A CB  1 
ATOM 887  C CG  . ASN A 1 121  ? 129.388 81.731  113.556 1.00 132.85 ? 121  ASN A CG  1 
ATOM 888  O OD1 . ASN A 1 121  ? 129.719 81.011  112.615 1.00 145.39 ? 121  ASN A OD1 1 
ATOM 889  N ND2 . ASN A 1 121  ? 129.910 81.606  114.765 1.00 144.79 ? 121  ASN A ND2 1 
ATOM 890  N N   . TRP A 1 122  ? 126.482 84.880  112.100 1.00 93.18  ? 122  TRP A N   1 
ATOM 891  C CA  . TRP A 1 122  ? 125.295 85.713  112.197 1.00 85.45  ? 122  TRP A CA  1 
ATOM 892  C C   . TRP A 1 122  ? 124.339 85.369  111.064 1.00 77.17  ? 122  TRP A C   1 
ATOM 893  O O   . TRP A 1 122  ? 123.207 84.976  111.315 1.00 73.10  ? 122  TRP A O   1 
ATOM 894  C CB  . TRP A 1 122  ? 125.644 87.211  112.216 1.00 82.76  ? 122  TRP A CB  1 
ATOM 895  C CG  . TRP A 1 122  ? 125.963 87.739  113.582 1.00 72.23  ? 122  TRP A CG  1 
ATOM 896  C CD1 . TRP A 1 122  ? 127.197 87.836  114.152 1.00 70.18  ? 122  TRP A CD1 1 
ATOM 897  C CD2 . TRP A 1 122  ? 125.038 88.267  114.545 1.00 70.23  ? 122  TRP A CD2 1 
ATOM 898  N NE1 . TRP A 1 122  ? 127.102 88.360  115.409 1.00 70.58  ? 122  TRP A NE1 1 
ATOM 899  C CE2 . TRP A 1 122  ? 125.793 88.641  115.675 1.00 76.73  ? 122  TRP A CE2 1 
ATOM 900  C CE3 . TRP A 1 122  ? 123.652 88.445  114.575 1.00 77.55  ? 122  TRP A CE3 1 
ATOM 901  C CZ2 . TRP A 1 122  ? 125.209 89.182  116.822 1.00 98.02  ? 122  TRP A CZ2 1 
ATOM 902  C CZ3 . TRP A 1 122  ? 123.075 88.997  115.700 1.00 93.67  ? 122  TRP A CZ3 1 
ATOM 903  C CH2 . TRP A 1 122  ? 123.844 89.358  116.813 1.00 103.61 ? 122  TRP A CH2 1 
ATOM 904  N N   . LEU A 1 123  ? 124.808 85.512  109.823 1.00 80.30  ? 123  LEU A N   1 
ATOM 905  C CA  . LEU A 1 123  ? 123.924 85.382  108.679 1.00 84.72  ? 123  LEU A CA  1 
ATOM 906  C C   . LEU A 1 123  ? 123.254 84.017  108.704 1.00 90.90  ? 123  LEU A C   1 
ATOM 907  O O   . LEU A 1 123  ? 122.050 83.930  108.494 1.00 107.17 ? 123  LEU A O   1 
ATOM 908  C CB  . LEU A 1 123  ? 124.692 85.606  107.376 1.00 86.56  ? 123  LEU A CB  1 
ATOM 909  C CG  . LEU A 1 123  ? 124.956 87.069  107.029 1.00 98.38  ? 123  LEU A CG  1 
ATOM 910  C CD1 . LEU A 1 123  ? 125.448 87.183  105.599 1.00 109.65 ? 123  LEU A CD1 1 
ATOM 911  C CD2 . LEU A 1 123  ? 123.709 87.916  107.251 1.00 105.53 ? 123  LEU A CD2 1 
ATOM 912  N N   . SER A 1 124  ? 124.020 82.961  108.977 1.00 87.60  ? 124  SER A N   1 
ATOM 913  C CA  . SER A 1 124  ? 123.392 81.683  109.244 1.00 90.82  ? 124  SER A CA  1 
ATOM 914  C C   . SER A 1 124  ? 122.437 81.861  110.417 1.00 84.64  ? 124  SER A C   1 
ATOM 915  O O   . SER A 1 124  ? 121.256 81.543  110.313 1.00 83.73  ? 124  SER A O   1 
ATOM 916  C CB  . SER A 1 124  ? 124.404 80.608  109.506 1.00 103.37 ? 124  SER A CB  1 
ATOM 917  O OG  . SER A 1 124  ? 125.411 81.066  110.392 1.00 105.57 ? 124  SER A OG  1 
ATOM 918  N N   . GLY A 1 125  ? 122.957 82.460  111.491 1.00 84.96  ? 125  GLY A N   1 
ATOM 919  C CA  . GLY A 1 125  ? 122.255 82.543  112.761 1.00 92.56  ? 125  GLY A CA  1 
ATOM 920  C C   . GLY A 1 125  ? 120.879 83.188  112.625 1.00 90.92  ? 125  GLY A C   1 
ATOM 921  O O   . GLY A 1 125  ? 119.860 82.559  112.892 1.00 87.68  ? 125  GLY A O   1 
ATOM 922  N N   . LEU A 1 126  ? 120.858 84.455  112.206 1.00 81.32  ? 126  LEU A N   1 
ATOM 923  C CA  . LEU A 1 126  ? 119.611 85.195  112.187 1.00 71.24  ? 126  LEU A CA  1 
ATOM 924  C C   . LEU A 1 126  ? 118.589 84.388  111.401 1.00 67.52  ? 126  LEU A C   1 
ATOM 925  O O   . LEU A 1 126  ? 117.456 84.235  111.848 1.00 71.34  ? 126  LEU A O   1 
ATOM 926  C CB  . LEU A 1 126  ? 119.847 86.592  111.610 1.00 65.20  ? 126  LEU A CB  1 
ATOM 927  C CG  . LEU A 1 126  ? 120.711 87.497  112.487 1.00 65.16  ? 126  LEU A CG  1 
ATOM 928  C CD1 . LEU A 1 126  ? 120.818 88.879  111.875 1.00 69.65  ? 126  LEU A CD1 1 
ATOM 929  C CD2 . LEU A 1 126  ? 120.161 87.590  113.908 1.00 65.31  ? 126  LEU A CD2 1 
ATOM 930  N N   . LYS A 1 127  ? 119.031 83.789  110.295 1.00 65.81  ? 127  LYS A N   1 
ATOM 931  C CA  . LYS A 1 127  ? 118.152 82.953  109.504 1.00 76.24  ? 127  LYS A CA  1 
ATOM 932  C C   . LYS A 1 127  ? 117.638 81.800  110.364 1.00 77.47  ? 127  LYS A C   1 
ATOM 933  O O   . LYS A 1 127  ? 116.451 81.488  110.287 1.00 88.79  ? 127  LYS A O   1 
ATOM 934  C CB  . LYS A 1 127  ? 118.846 82.461  108.231 1.00 97.18  ? 127  LYS A CB  1 
ATOM 935  C CG  . LYS A 1 127  ? 117.908 82.009  107.117 1.00 121.72 ? 127  LYS A CG  1 
ATOM 936  C CD  . LYS A 1 127  ? 117.292 80.636  107.328 1.00 142.32 ? 127  LYS A CD  1 
ATOM 937  C CE  . LYS A 1 127  ? 116.086 80.379  106.447 1.00 154.65 ? 127  LYS A CE  1 
ATOM 938  N NZ  . LYS A 1 127  ? 116.434 80.423  105.006 1.00 160.62 ? 127  LYS A NZ  1 
ATOM 939  N N   . ILE A 1 128  ? 118.505 81.172  111.175 1.00 76.06  ? 128  ILE A N   1 
ATOM 940  C CA  . ILE A 1 128  ? 118.076 80.016  111.956 1.00 81.17  ? 128  ILE A CA  1 
ATOM 941  C C   . ILE A 1 128  ? 116.942 80.462  112.879 1.00 79.60  ? 128  ILE A C   1 
ATOM 942  O O   . ILE A 1 128  ? 115.905 79.802  112.938 1.00 76.59  ? 128  ILE A O   1 
ATOM 943  C CB  . ILE A 1 128  ? 119.215 79.336  112.755 1.00 90.08  ? 128  ILE A CB  1 
ATOM 944  C CG1 . ILE A 1 128  ? 120.513 79.149  111.961 1.00 100.64 ? 128  ILE A CG1 1 
ATOM 945  C CG2 . ILE A 1 128  ? 118.744 78.008  113.331 1.00 91.71  ? 128  ILE A CG2 1 
ATOM 946  C CD1 . ILE A 1 128  ? 120.379 78.301  110.711 1.00 111.29 ? 128  ILE A CD1 1 
ATOM 947  N N   . LEU A 1 129  ? 117.134 81.608  113.556 1.00 74.76  ? 129  LEU A N   1 
ATOM 948  C CA  . LEU A 1 129  ? 116.168 82.113  114.519 1.00 68.49  ? 129  LEU A CA  1 
ATOM 949  C C   . LEU A 1 129  ? 114.892 82.530  113.803 1.00 66.02  ? 129  LEU A C   1 
ATOM 950  O O   . LEU A 1 129  ? 113.800 82.177  114.242 1.00 65.43  ? 129  LEU A O   1 
ATOM 951  C CB  . LEU A 1 129  ? 116.771 83.294  115.282 1.00 66.83  ? 129  LEU A CB  1 
ATOM 952  C CG  . LEU A 1 129  ? 118.056 82.970  116.037 1.00 74.73  ? 129  LEU A CG  1 
ATOM 953  C CD1 . LEU A 1 129  ? 118.415 84.092  116.983 1.00 72.82  ? 129  LEU A CD1 1 
ATOM 954  C CD2 . LEU A 1 129  ? 117.929 81.650  116.792 1.00 83.73  ? 129  LEU A CD2 1 
ATOM 955  N N   . HIS A 1 130  ? 115.048 83.285  112.713 1.00 66.77  ? 130  HIS A N   1 
ATOM 956  C CA  . HIS A 1 130  ? 113.894 83.825  112.022 1.00 71.83  ? 130  HIS A CA  1 
ATOM 957  C C   . HIS A 1 130  ? 112.972 82.691  111.600 1.00 74.56  ? 130  HIS A C   1 
ATOM 958  O O   . HIS A 1 130  ? 111.760 82.827  111.691 1.00 86.51  ? 130  HIS A O   1 
ATOM 959  C CB  . HIS A 1 130  ? 114.285 84.676  110.814 1.00 76.47  ? 130  HIS A CB  1 
ATOM 960  C CG  . HIS A 1 130  ? 113.103 85.176  110.046 1.00 83.04  ? 130  HIS A CG  1 
ATOM 961  N ND1 . HIS A 1 130  ? 112.229 84.345  109.376 1.00 85.59  ? 130  HIS A ND1 1 
ATOM 962  C CD2 . HIS A 1 130  ? 112.660 86.423  109.838 1.00 87.50  ? 130  HIS A CD2 1 
ATOM 963  C CE1 . HIS A 1 130  ? 111.299 85.075  108.781 1.00 86.87  ? 130  HIS A CE1 1 
ATOM 964  N NE2 . HIS A 1 130  ? 111.537 86.338  109.055 1.00 88.47  ? 130  HIS A NE2 1 
ATOM 965  N N   . GLN A 1 131  ? 113.537 81.585  111.125 1.00 84.08  ? 131  GLN A N   1 
ATOM 966  C CA  . GLN A 1 131  ? 112.704 80.465  110.730 1.00 107.75 ? 131  GLN A CA  1 
ATOM 967  C C   . GLN A 1 131  ? 111.861 80.062  111.937 1.00 116.10 ? 131  GLN A C   1 
ATOM 968  O O   . GLN A 1 131  ? 110.651 79.875  111.812 1.00 124.71 ? 131  GLN A O   1 
ATOM 969  C CB  . GLN A 1 131  ? 113.544 79.297  110.204 1.00 132.81 ? 131  GLN A CB  1 
ATOM 970  C CG  . GLN A 1 131  ? 113.040 78.711  108.885 1.00 150.05 ? 131  GLN A CG  1 
ATOM 971  C CD  . GLN A 1 131  ? 111.575 78.342  108.889 1.00 156.55 ? 131  GLN A CD  1 
ATOM 972  O OE1 . GLN A 1 131  ? 110.787 78.847  108.091 1.00 152.90 ? 131  GLN A OE1 1 
ATOM 973  N NE2 . GLN A 1 131  ? 111.199 77.448  109.790 1.00 157.42 ? 131  GLN A NE2 1 
ATOM 974  N N   . GLU A 1 132  ? 112.499 79.981  113.113 1.00 121.28 ? 132  GLU A N   1 
ATOM 975  C CA  . GLU A 1 132  ? 111.824 79.528  114.321 1.00 130.55 ? 132  GLU A CA  1 
ATOM 976  C C   . GLU A 1 132  ? 110.632 80.432  114.623 1.00 112.35 ? 132  GLU A C   1 
ATOM 977  O O   . GLU A 1 132  ? 109.497 79.962  114.649 1.00 105.31 ? 132  GLU A O   1 
ATOM 978  C CB  . GLU A 1 132  ? 112.775 79.500  115.519 1.00 154.02 ? 132  GLU A CB  1 
ATOM 979  C CG  . GLU A 1 132  ? 113.945 78.550  115.349 1.00 179.49 ? 132  GLU A CG  1 
ATOM 980  C CD  . GLU A 1 132  ? 114.925 78.526  116.511 1.00 195.04 ? 132  GLU A CD  1 
ATOM 981  O OE1 . GLU A 1 132  ? 115.918 77.780  116.418 1.00 193.74 ? 132  GLU A OE1 1 
ATOM 982  O OE2 . GLU A 1 132  ? 114.695 79.251  117.506 1.00 201.53 ? 132  GLU A OE2 1 
ATOM 983  N N   . ALA A 1 133  ? 110.901 81.727  114.837 1.00 93.65  ? 133  ALA A N   1 
ATOM 984  C CA  . ALA A 1 133  ? 109.872 82.676  115.230 1.00 82.17  ? 133  ALA A CA  1 
ATOM 985  C C   . ALA A 1 133  ? 108.609 82.444  114.414 1.00 76.26  ? 133  ALA A C   1 
ATOM 986  O O   . ALA A 1 133  ? 107.549 82.181  114.971 1.00 82.23  ? 133  ALA A O   1 
ATOM 987  C CB  . ALA A 1 133  ? 110.370 84.091  115.070 1.00 81.91  ? 133  ALA A CB  1 
ATOM 988  N N   . MET A 1 134  ? 108.733 82.515  113.092 1.00 77.05  ? 134  MET A N   1 
ATOM 989  C CA  . MET A 1 134  ? 107.558 82.416  112.251 1.00 89.66  ? 134  MET A CA  1 
ATOM 990  C C   . MET A 1 134  ? 106.783 81.158  112.633 1.00 95.96  ? 134  MET A C   1 
ATOM 991  O O   . MET A 1 134  ? 105.560 81.145  112.559 1.00 105.59 ? 134  MET A O   1 
ATOM 992  C CB  . MET A 1 134  ? 107.908 82.403  110.759 1.00 108.92 ? 134  MET A CB  1 
ATOM 993  C CG  . MET A 1 134  ? 107.358 83.603  109.983 1.00 131.19 ? 134  MET A CG  1 
ATOM 994  S SD  . MET A 1 134  ? 108.407 85.091  109.915 1.00 155.84 ? 134  MET A SD  1 
ATOM 995  C CE  . MET A 1 134  ? 109.140 85.145  111.549 1.00 144.60 ? 134  MET A CE  1 
ATOM 996  N N   . ASN A 1 135  ? 107.473 80.114  113.093 1.00 101.01 ? 135  ASN A N   1 
ATOM 997  C CA  . ASN A 1 135  ? 106.761 78.898  113.441 1.00 111.63 ? 135  ASN A CA  1 
ATOM 998  C C   . ASN A 1 135  ? 106.592 78.739  114.949 1.00 104.07 ? 135  ASN A C   1 
ATOM 999  O O   . ASN A 1 135  ? 106.131 77.690  115.388 1.00 115.53 ? 135  ASN A O   1 
ATOM 1000 C CB  . ASN A 1 135  ? 107.395 77.663  112.800 1.00 129.81 ? 135  ASN A CB  1 
ATOM 1001 C CG  . ASN A 1 135  ? 106.502 77.075  111.728 1.00 143.82 ? 135  ASN A CG  1 
ATOM 1002 O OD1 . ASN A 1 135  ? 106.026 75.950  111.862 1.00 151.36 ? 135  ASN A OD1 1 
ATOM 1003 N ND2 . ASN A 1 135  ? 106.237 77.843  110.682 1.00 146.73 ? 135  ASN A ND2 1 
ATOM 1004 N N   . ALA A 1 136  ? 106.913 79.770  115.738 1.00 94.22  ? 136  ALA A N   1 
ATOM 1005 C CA  . ALA A 1 136  ? 106.612 79.737  117.161 1.00 89.37  ? 136  ALA A CA  1 
ATOM 1006 C C   . ALA A 1 136  ? 105.100 79.648  117.337 1.00 84.37  ? 136  ALA A C   1 
ATOM 1007 O O   . ALA A 1 136  ? 104.357 80.283  116.595 1.00 86.48  ? 136  ALA A O   1 
ATOM 1008 C CB  . ALA A 1 136  ? 107.169 80.952  117.859 1.00 90.65  ? 136  ALA A CB  1 
ATOM 1009 N N   . SER A 1 137  ? 104.657 78.836  118.300 1.00 86.99  ? 137  SER A N   1 
ATOM 1010 C CA  . SER A 1 137  ? 103.238 78.670  118.570 1.00 97.24  ? 137  SER A CA  1 
ATOM 1011 C C   . SER A 1 137  ? 102.747 79.850  119.402 1.00 99.87  ? 137  SER A C   1 
ATOM 1012 O O   . SER A 1 137  ? 103.546 80.495  120.070 1.00 104.52 ? 137  SER A O   1 
ATOM 1013 C CB  . SER A 1 137  ? 102.978 77.365  119.270 1.00 111.23 ? 137  SER A CB  1 
ATOM 1014 O OG  . SER A 1 137  ? 101.589 77.170  119.464 1.00 118.78 ? 137  SER A OG  1 
ATOM 1015 N N   . THR A 1 138  ? 101.435 80.117  119.382 1.00 92.60  ? 138  THR A N   1 
ATOM 1016 C CA  . THR A 1 138  ? 100.897 81.329  119.985 1.00 90.00  ? 138  THR A CA  1 
ATOM 1017 C C   . THR A 1 138  ? 101.350 81.478  121.437 1.00 77.69  ? 138  THR A C   1 
ATOM 1018 O O   . THR A 1 138  ? 101.865 82.525  121.816 1.00 69.47  ? 138  THR A O   1 
ATOM 1019 C CB  . THR A 1 138  ? 99.370  81.405  119.871 1.00 94.85  ? 138  THR A CB  1 
ATOM 1020 O OG1 . THR A 1 138  ? 99.023  82.721  120.304 1.00 97.29  ? 138  THR A OG1 1 
ATOM 1021 C CG2 . THR A 1 138  ? 98.653  80.361  120.706 1.00 98.92  ? 138  THR A CG2 1 
ATOM 1022 N N   . PRO A 1 139  ? 101.140 80.473  122.310 1.00 72.16  ? 139  PRO A N   1 
ATOM 1023 C CA  . PRO A 1 139  ? 101.525 80.610  123.713 1.00 70.44  ? 139  PRO A CA  1 
ATOM 1024 C C   . PRO A 1 139  ? 102.988 80.987  123.910 1.00 60.89  ? 139  PRO A C   1 
ATOM 1025 O O   . PRO A 1 139  ? 103.313 81.692  124.857 1.00 67.54  ? 139  PRO A O   1 
ATOM 1026 C CB  . PRO A 1 139  ? 101.215 79.222  124.282 1.00 80.64  ? 139  PRO A CB  1 
ATOM 1027 C CG  . PRO A 1 139  ? 100.070 78.747  123.410 1.00 81.83  ? 139  PRO A CG  1 
ATOM 1028 C CD  . PRO A 1 139  ? 100.490 79.185  122.024 1.00 76.85  ? 139  PRO A CD  1 
ATOM 1029 N N   . THR A 1 140  ? 103.869 80.525  123.027 1.00 57.60  ? 140  THR A N   1 
ATOM 1030 C CA  . THR A 1 140  ? 105.272 80.863  123.157 1.00 66.82  ? 140  THR A CA  1 
ATOM 1031 C C   . THR A 1 140  ? 105.491 82.341  122.847 1.00 73.81  ? 140  THR A C   1 
ATOM 1032 O O   . THR A 1 140  ? 106.336 82.966  123.484 1.00 85.03  ? 140  THR A O   1 
ATOM 1033 C CB  . THR A 1 140  ? 106.167 79.995  122.267 1.00 83.49  ? 140  THR A CB  1 
ATOM 1034 O OG1 . THR A 1 140  ? 105.948 78.626  122.613 1.00 99.97  ? 140  THR A OG1 1 
ATOM 1035 C CG2 . THR A 1 140  ? 107.636 80.337  122.420 1.00 85.86  ? 140  THR A CG2 1 
ATOM 1036 N N   . ILE A 1 141  ? 104.730 82.903  121.893 1.00 71.67  ? 141  ILE A N   1 
ATOM 1037 C CA  . ILE A 1 141  ? 104.924 84.297  121.504 1.00 67.86  ? 141  ILE A CA  1 
ATOM 1038 C C   . ILE A 1 141  ? 104.558 85.176  122.696 1.00 64.87  ? 141  ILE A C   1 
ATOM 1039 O O   . ILE A 1 141  ? 105.340 86.036  123.087 1.00 56.52  ? 141  ILE A O   1 
ATOM 1040 C CB  . ILE A 1 141  ? 104.116 84.729  120.260 1.00 69.83  ? 141  ILE A CB  1 
ATOM 1041 C CG1 . ILE A 1 141  ? 103.751 83.559  119.347 1.00 80.02  ? 141  ILE A CG1 1 
ATOM 1042 C CG2 . ILE A 1 141  ? 104.855 85.824  119.500 1.00 72.94  ? 141  ILE A CG2 1 
ATOM 1043 C CD1 . ILE A 1 141  ? 103.020 83.972  118.087 1.00 87.90  ? 141  ILE A CD1 1 
ATOM 1044 N N   . ILE A 1 142  ? 103.377 84.922  123.283 1.00 59.15  ? 142  ILE A N   1 
ATOM 1045 C CA  . ILE A 1 142  ? 102.867 85.766  124.346 1.00 50.69  ? 142  ILE A CA  1 
ATOM 1046 C C   . ILE A 1 142  ? 103.982 85.971  125.355 1.00 48.39  ? 142  ILE A C   1 
ATOM 1047 O O   . ILE A 1 142  ? 104.283 87.105  125.692 1.00 50.44  ? 142  ILE A O   1 
ATOM 1048 C CB  . ILE A 1 142  ? 101.601 85.186  124.997 1.00 52.48  ? 142  ILE A CB  1 
ATOM 1049 C CG1 . ILE A 1 142  ? 100.426 85.207  124.019 1.00 58.00  ? 142  ILE A CG1 1 
ATOM 1050 C CG2 . ILE A 1 142  ? 101.271 85.931  126.280 1.00 57.03  ? 142  ILE A CG2 1 
ATOM 1051 C CD1 . ILE A 1 142  ? 99.061  85.015  124.664 1.00 67.59  ? 142  ILE A CD1 1 
ATOM 1052 N N   . GLU A 1 143  ? 104.578 84.873  125.826 1.00 55.73  ? 143  GLU A N   1 
ATOM 1053 C CA  . GLU A 1 143  ? 105.624 84.955  126.824 1.00 67.81  ? 143  GLU A CA  1 
ATOM 1054 C C   . GLU A 1 143  ? 106.606 86.041  126.414 1.00 62.73  ? 143  GLU A C   1 
ATOM 1055 O O   . GLU A 1 143  ? 106.982 86.874  127.232 1.00 71.77  ? 143  GLU A O   1 
ATOM 1056 C CB  . GLU A 1 143  ? 106.355 83.623  127.001 1.00 90.02  ? 143  GLU A CB  1 
ATOM 1057 C CG  . GLU A 1 143  ? 107.709 83.773  127.685 1.00 115.04 ? 143  GLU A CG  1 
ATOM 1058 C CD  . GLU A 1 143  ? 108.350 82.496  128.214 1.00 134.51 ? 143  GLU A CD  1 
ATOM 1059 O OE1 . GLU A 1 143  ? 109.508 82.573  128.685 1.00 135.53 ? 143  GLU A OE1 1 
ATOM 1060 O OE2 . GLU A 1 143  ? 107.694 81.429  128.172 1.00 142.46 ? 143  GLU A OE2 1 
ATOM 1061 N N   . SER A 1 144  ? 107.041 86.014  125.159 1.00 59.16  ? 144  SER A N   1 
ATOM 1062 C CA  . SER A 1 144  ? 108.052 86.960  124.728 1.00 72.19  ? 144  SER A CA  1 
ATOM 1063 C C   . SER A 1 144  ? 107.534 88.390  124.856 1.00 72.64  ? 144  SER A C   1 
ATOM 1064 O O   . SER A 1 144  ? 108.223 89.259  125.385 1.00 72.90  ? 144  SER A O   1 
ATOM 1065 C CB  . SER A 1 144  ? 108.506 86.685  123.335 1.00 83.33  ? 144  SER A CB  1 
ATOM 1066 O OG  . SER A 1 144  ? 109.503 87.624  122.970 1.00 84.06  ? 144  SER A OG  1 
ATOM 1067 N N   . TRP A 1 145  ? 106.315 88.619  124.360 1.00 71.99  ? 145  TRP A N   1 
ATOM 1068 C CA  . TRP A 1 145  ? 105.690 89.926  124.453 1.00 72.65  ? 145  TRP A CA  1 
ATOM 1069 C C   . TRP A 1 145  ? 105.760 90.395  125.900 1.00 65.51  ? 145  TRP A C   1 
ATOM 1070 O O   . TRP A 1 145  ? 106.358 91.425  126.190 1.00 61.46  ? 145  TRP A O   1 
ATOM 1071 C CB  . TRP A 1 145  ? 104.240 89.879  123.939 1.00 78.09  ? 145  TRP A CB  1 
ATOM 1072 C CG  . TRP A 1 145  ? 103.544 91.201  123.970 1.00 74.19  ? 145  TRP A CG  1 
ATOM 1073 C CD1 . TRP A 1 145  ? 103.834 92.276  123.193 1.00 76.38  ? 145  TRP A CD1 1 
ATOM 1074 C CD2 . TRP A 1 145  ? 102.472 91.603  124.838 1.00 82.27  ? 145  TRP A CD2 1 
ATOM 1075 N NE1 . TRP A 1 145  ? 103.012 93.318  123.505 1.00 85.87  ? 145  TRP A NE1 1 
ATOM 1076 C CE2 . TRP A 1 145  ? 102.168 92.939  124.511 1.00 88.37  ? 145  TRP A CE2 1 
ATOM 1077 C CE3 . TRP A 1 145  ? 101.740 90.979  125.858 1.00 105.23 ? 145  TRP A CE3 1 
ATOM 1078 C CZ2 . TRP A 1 145  ? 101.171 93.665  125.162 1.00 113.19 ? 145  TRP A CZ2 1 
ATOM 1079 C CZ3 . TRP A 1 145  ? 100.759 91.701  126.506 1.00 121.29 ? 145  TRP A CZ3 1 
ATOM 1080 C CH2 . TRP A 1 145  ? 100.477 93.025  126.160 1.00 122.24 ? 145  TRP A CH2 1 
ATOM 1081 N N   . LEU A 1 146  ? 105.147 89.618  126.801 1.00 58.76  ? 146  LEU A N   1 
ATOM 1082 C CA  . LEU A 1 146  ? 105.096 90.013  128.189 1.00 51.67  ? 146  LEU A CA  1 
ATOM 1083 C C   . LEU A 1 146  ? 106.523 90.338  128.588 1.00 49.81  ? 146  LEU A C   1 
ATOM 1084 O O   . LEU A 1 146  ? 106.774 91.400  129.133 1.00 59.05  ? 146  LEU A O   1 
ATOM 1085 C CB  . LEU A 1 146  ? 104.483 88.905  129.044 1.00 54.69  ? 146  LEU A CB  1 
ATOM 1086 C CG  . LEU A 1 146  ? 102.970 88.730  128.909 1.00 64.70  ? 146  LEU A CG  1 
ATOM 1087 C CD1 . LEU A 1 146  ? 102.484 87.578  129.779 1.00 75.95  ? 146  LEU A CD1 1 
ATOM 1088 C CD2 . LEU A 1 146  ? 102.230 90.004  129.287 1.00 67.47  ? 146  LEU A CD2 1 
ATOM 1089 N N   . ARG A 1 147  ? 107.469 89.470  128.240 1.00 50.46  ? 147  ARG A N   1 
ATOM 1090 C CA  . ARG A 1 147  ? 108.848 89.756  128.575 1.00 60.37  ? 147  ARG A CA  1 
ATOM 1091 C C   . ARG A 1 147  ? 109.228 91.099  127.973 1.00 65.70  ? 147  ARG A C   1 
ATOM 1092 O O   . ARG A 1 147  ? 109.909 91.885  128.619 1.00 71.40  ? 147  ARG A O   1 
ATOM 1093 C CB  . ARG A 1 147  ? 109.817 88.673  128.098 1.00 70.14  ? 147  ARG A CB  1 
ATOM 1094 C CG  . ARG A 1 147  ? 111.277 88.949  128.450 1.00 79.03  ? 147  ARG A CG  1 
ATOM 1095 C CD  . ARG A 1 147  ? 111.716 88.418  129.806 1.00 85.43  ? 147  ARG A CD  1 
ATOM 1096 N NE  . ARG A 1 147  ? 111.414 86.999  129.975 1.00 84.61  ? 147  ARG A NE  1 
ATOM 1097 C CZ  . ARG A 1 147  ? 111.745 86.275  131.037 1.00 83.86  ? 147  ARG A CZ  1 
ATOM 1098 N NH1 . ARG A 1 147  ? 112.647 86.719  131.897 1.00 83.65  ? 147  ARG A NH1 1 
ATOM 1099 N NH2 . ARG A 1 147  ? 111.197 85.084  131.209 1.00 84.44  ? 147  ARG A NH2 1 
ATOM 1100 N N   . LYS A 1 148  ? 108.794 91.361  126.741 1.00 72.97  ? 148  LYS A N   1 
ATOM 1101 C CA  . LYS A 1 148  ? 109.195 92.592  126.079 1.00 83.99  ? 148  LYS A CA  1 
ATOM 1102 C C   . LYS A 1 148  ? 108.713 93.776  126.918 1.00 78.47  ? 148  LYS A C   1 
ATOM 1103 O O   . LYS A 1 148  ? 109.477 94.701  127.188 1.00 78.34  ? 148  LYS A O   1 
ATOM 1104 C CB  . LYS A 1 148  ? 108.656 92.626  124.645 1.00 88.66  ? 148  LYS A CB  1 
ATOM 1105 C CG  . LYS A 1 148  ? 109.581 93.281  123.629 1.00 88.97  ? 148  LYS A CG  1 
ATOM 1106 C CD  . LYS A 1 148  ? 109.066 93.230  122.205 1.00 89.25  ? 148  LYS A CD  1 
ATOM 1107 C CE  . LYS A 1 148  ? 108.784 91.824  121.720 1.00 88.21  ? 148  LYS A CE  1 
ATOM 1108 N NZ  . LYS A 1 148  ? 108.004 91.809  120.459 1.00 89.11  ? 148  LYS A NZ  1 
ATOM 1109 N N   . GLN A 1 149  ? 107.449 93.717  127.349 1.00 68.74  ? 149  GLN A N   1 
ATOM 1110 C CA  . GLN A 1 149  ? 106.837 94.809  128.084 1.00 64.77  ? 149  GLN A CA  1 
ATOM 1111 C C   . GLN A 1 149  ? 107.659 95.079  129.344 1.00 67.14  ? 149  GLN A C   1 
ATOM 1112 O O   . GLN A 1 149  ? 108.069 96.210  129.586 1.00 68.55  ? 149  GLN A O   1 
ATOM 1113 C CB  . GLN A 1 149  ? 105.365 94.492  128.376 1.00 64.74  ? 149  GLN A CB  1 
ATOM 1114 C CG  . GLN A 1 149  ? 104.510 94.296  127.128 1.00 66.27  ? 149  GLN A CG  1 
ATOM 1115 C CD  . GLN A 1 149  ? 104.441 95.557  126.307 1.00 78.41  ? 149  GLN A CD  1 
ATOM 1116 O OE1 . GLN A 1 149  ? 104.708 96.651  126.802 1.00 88.62  ? 149  GLN A OE1 1 
ATOM 1117 N NE2 . GLN A 1 149  ? 104.034 95.425  125.055 1.00 85.93  ? 149  GLN A NE2 1 
ATOM 1118 N N   . ILE A 1 150  ? 107.935 94.034  130.129 1.00 68.17  ? 150  ILE A N   1 
ATOM 1119 C CA  . ILE A 1 150  ? 108.705 94.201  131.349 1.00 67.05  ? 150  ILE A CA  1 
ATOM 1120 C C   . ILE A 1 150  ? 110.003 94.919  131.007 1.00 65.22  ? 150  ILE A C   1 
ATOM 1121 O O   . ILE A 1 150  ? 110.422 95.820  131.724 1.00 71.67  ? 150  ILE A O   1 
ATOM 1122 C CB  . ILE A 1 150  ? 108.980 92.858  132.051 1.00 72.39  ? 150  ILE A CB  1 
ATOM 1123 C CG1 . ILE A 1 150  ? 107.730 92.315  132.746 1.00 79.19  ? 150  ILE A CG1 1 
ATOM 1124 C CG2 . ILE A 1 150  ? 110.142 93.001  133.022 1.00 77.72  ? 150  ILE A CG2 1 
ATOM 1125 C CD1 . ILE A 1 150  ? 107.956 91.014  133.482 1.00 88.76  ? 150  ILE A CD1 1 
ATOM 1126 N N   . TYR A 1 151  ? 110.637 94.508  129.911 1.00 70.54  ? 151  TYR A N   1 
ATOM 1127 C CA  . TYR A 1 151  ? 111.868 95.140  129.476 1.00 87.78  ? 151  TYR A CA  1 
ATOM 1128 C C   . TYR A 1 151  ? 111.631 96.625  129.196 1.00 91.55  ? 151  TYR A C   1 
ATOM 1129 O O   . TYR A 1 151  ? 112.568 97.414  129.261 1.00 92.23  ? 151  TYR A O   1 
ATOM 1130 C CB  . TYR A 1 151  ? 112.444 94.426  128.248 1.00 105.93 ? 151  TYR A CB  1 
ATOM 1131 C CG  . TYR A 1 151  ? 113.358 93.254  128.525 1.00 116.51 ? 151  TYR A CG  1 
ATOM 1132 C CD1 . TYR A 1 151  ? 112.970 92.186  129.327 1.00 115.63 ? 151  TYR A CD1 1 
ATOM 1133 C CD2 . TYR A 1 151  ? 114.612 93.191  127.938 1.00 120.28 ? 151  TYR A CD2 1 
ATOM 1134 C CE1 . TYR A 1 151  ? 113.811 91.109  129.561 1.00 110.95 ? 151  TYR A CE1 1 
ATOM 1135 C CE2 . TYR A 1 151  ? 115.463 92.119  128.159 1.00 118.10 ? 151  TYR A CE2 1 
ATOM 1136 C CZ  . TYR A 1 151  ? 115.063 91.072  128.972 1.00 113.48 ? 151  TYR A CZ  1 
ATOM 1137 O OH  . TYR A 1 151  ? 115.916 90.015  129.189 1.00 110.21 ? 151  TYR A OH  1 
ATOM 1138 N N   . SER A 1 152  ? 110.385 97.009  128.887 1.00 93.35  ? 152  SER A N   1 
ATOM 1139 C CA  . SER A 1 152  ? 110.069 98.381  128.518 1.00 101.22 ? 152  SER A CA  1 
ATOM 1140 C C   . SER A 1 152  ? 110.223 99.349  129.692 1.00 104.87 ? 152  SER A C   1 
ATOM 1141 O O   . SER A 1 152  ? 110.833 100.403 129.517 1.00 110.37 ? 152  SER A O   1 
ATOM 1142 C CB  . SER A 1 152  ? 108.687 98.492  127.921 1.00 103.65 ? 152  SER A CB  1 
ATOM 1143 O OG  . SER A 1 152  ? 108.382 99.845  127.613 1.00 108.31 ? 152  SER A OG  1 
ATOM 1144 N N   . VAL A 1 153  ? 109.639 99.023  130.858 1.00 101.37 ? 153  VAL A N   1 
ATOM 1145 C CA  . VAL A 1 153  ? 109.518 99.985  131.950 1.00 100.08 ? 153  VAL A CA  1 
ATOM 1146 C C   . VAL A 1 153  ? 110.871 100.639 132.195 1.00 100.92 ? 153  VAL A C   1 
ATOM 1147 O O   . VAL A 1 153  ? 110.978 101.862 132.244 1.00 110.39 ? 153  VAL A O   1 
ATOM 1148 C CB  . VAL A 1 153  ? 108.980 99.377  133.261 1.00 104.60 ? 153  VAL A CB  1 
ATOM 1149 C CG1 . VAL A 1 153  ? 107.515 98.981  133.150 1.00 111.97 ? 153  VAL A CG1 1 
ATOM 1150 C CG2 . VAL A 1 153  ? 109.818 98.212  133.762 1.00 106.18 ? 153  VAL A CG2 1 
ATOM 1151 N N   . ASP A 1 154  ? 111.882 99.793  132.370 1.00 112.61 ? 154  ASP A N   1 
ATOM 1152 C CA  . ASP A 1 154  ? 113.265 100.214 132.427 1.00 145.82 ? 154  ASP A CA  1 
ATOM 1153 C C   . ASP A 1 154  ? 113.927 99.515  131.253 1.00 157.28 ? 154  ASP A C   1 
ATOM 1154 O O   . ASP A 1 154  ? 113.754 98.312  131.096 1.00 166.89 ? 154  ASP A O   1 
ATOM 1155 C CB  . ASP A 1 154  ? 113.893 99.851  133.774 1.00 175.10 ? 154  ASP A CB  1 
ATOM 1156 C CG  . ASP A 1 154  ? 115.379 100.148 133.882 1.00 197.90 ? 154  ASP A CG  1 
ATOM 1157 O OD1 . ASP A 1 154  ? 116.127 99.727  132.979 1.00 210.61 ? 154  ASP A OD1 1 
ATOM 1158 O OD2 . ASP A 1 154  ? 115.778 100.786 134.878 1.00 207.94 ? 154  ASP A OD2 1 
ATOM 1159 N N   . GLN A 1 155  ? 114.650 100.269 130.426 1.00 170.16 ? 155  GLN A N   1 
ATOM 1160 C CA  . GLN A 1 155  ? 115.135 99.727  129.169 1.00 187.95 ? 155  GLN A CA  1 
ATOM 1161 C C   . GLN A 1 155  ? 115.900 98.432  129.453 1.00 182.36 ? 155  GLN A C   1 
ATOM 1162 O O   . GLN A 1 155  ? 115.652 97.414  128.810 1.00 172.84 ? 155  GLN A O   1 
ATOM 1163 C CB  . GLN A 1 155  ? 115.963 100.777 128.423 1.00 205.96 ? 155  GLN A CB  1 
ATOM 1164 C CG  . GLN A 1 155  ? 115.719 100.788 126.918 1.00 217.07 ? 155  GLN A CG  1 
ATOM 1165 C CD  . GLN A 1 155  ? 114.268 101.018 126.561 1.00 218.72 ? 155  GLN A CD  1 
ATOM 1166 O OE1 . GLN A 1 155  ? 113.660 100.249 125.821 1.00 213.77 ? 155  GLN A OE1 1 
ATOM 1167 N NE2 . GLN A 1 155  ? 113.693 102.085 127.093 1.00 222.86 ? 155  GLN A NE2 1 
ATOM 1168 N N   . THR A 1 156  ? 116.784 98.467  130.459 1.00 178.68 ? 156  THR A N   1 
ATOM 1169 C CA  . THR A 1 156  ? 117.588 97.313  130.833 1.00 178.64 ? 156  THR A CA  1 
ATOM 1170 C C   . THR A 1 156  ? 116.694 96.202  131.385 1.00 163.66 ? 156  THR A C   1 
ATOM 1171 O O   . THR A 1 156  ? 115.726 96.473  132.088 1.00 165.59 ? 156  THR A O   1 
ATOM 1172 C CB  . THR A 1 156  ? 118.658 97.701  131.862 1.00 193.99 ? 156  THR A CB  1 
ATOM 1173 O OG1 . THR A 1 156  ? 119.336 98.865  131.386 1.00 196.55 ? 156  THR A OG1 1 
ATOM 1174 C CG2 . THR A 1 156  ? 119.657 96.596  132.125 1.00 200.18 ? 156  THR A CG2 1 
ATOM 1175 N N   . ARG A 1 157  ? 117.047 94.954  131.062 1.00 152.83 ? 157  ARG A N   1 
ATOM 1176 C CA  . ARG A 1 157  ? 116.291 93.777  131.468 1.00 141.12 ? 157  ARG A CA  1 
ATOM 1177 C C   . ARG A 1 157  ? 116.128 93.713  132.985 1.00 131.21 ? 157  ARG A C   1 
ATOM 1178 O O   . ARG A 1 157  ? 117.095 93.843  133.731 1.00 128.99 ? 157  ARG A O   1 
ATOM 1179 C CB  . ARG A 1 157  ? 116.925 92.491  130.920 1.00 140.85 ? 157  ARG A CB  1 
ATOM 1180 C CG  . ARG A 1 157  ? 118.429 92.526  130.686 1.00 150.20 ? 157  ARG A CG  1 
ATOM 1181 C CD  . ARG A 1 157  ? 118.878 91.576  129.586 1.00 155.51 ? 157  ARG A CD  1 
ATOM 1182 N NE  . ARG A 1 157  ? 120.109 92.055  128.962 1.00 159.74 ? 157  ARG A NE  1 
ATOM 1183 C CZ  . ARG A 1 157  ? 121.240 91.365  128.859 1.00 162.37 ? 157  ARG A CZ  1 
ATOM 1184 N NH1 . ARG A 1 157  ? 121.289 90.099  129.232 1.00 169.18 ? 157  ARG A NH1 1 
ATOM 1185 N NH2 . ARG A 1 157  ? 122.322 91.945  128.369 1.00 157.77 ? 157  ARG A NH2 1 
ATOM 1186 N N   . ARG A 1 158  ? 114.875 93.506  133.410 1.00 122.46 ? 158  ARG A N   1 
ATOM 1187 C CA  . ARG A 1 158  ? 114.513 93.361  134.808 1.00 118.75 ? 158  ARG A CA  1 
ATOM 1188 C C   . ARG A 1 158  ? 113.591 92.153  134.944 1.00 110.37 ? 158  ARG A C   1 
ATOM 1189 O O   . ARG A 1 158  ? 112.721 91.934  134.110 1.00 104.54 ? 158  ARG A O   1 
ATOM 1190 C CB  . ARG A 1 158  ? 113.846 94.643  135.321 1.00 131.32 ? 158  ARG A CB  1 
ATOM 1191 C CG  . ARG A 1 158  ? 113.108 94.470  136.640 1.00 145.24 ? 158  ARG A CG  1 
ATOM 1192 C CD  . ARG A 1 158  ? 113.063 95.731  137.481 1.00 153.13 ? 158  ARG A CD  1 
ATOM 1193 N NE  . ARG A 1 158  ? 112.311 96.822  136.878 1.00 147.33 ? 158  ARG A NE  1 
ATOM 1194 C CZ  . ARG A 1 158  ? 112.832 97.989  136.515 1.00 146.44 ? 158  ARG A CZ  1 
ATOM 1195 N NH1 . ARG A 1 158  ? 112.033 99.000  136.223 1.00 152.86 ? 158  ARG A NH1 1 
ATOM 1196 N NH2 . ARG A 1 158  ? 114.143 98.166  136.511 1.00 141.41 ? 158  ARG A NH2 1 
ATOM 1197 N N   . ASN A 1 159  ? 113.781 91.376  136.012 1.00 118.10 ? 159  ASN A N   1 
ATOM 1198 C CA  . ASN A 1 159  ? 113.049 90.134  136.174 1.00 126.80 ? 159  ASN A CA  1 
ATOM 1199 C C   . ASN A 1 159  ? 111.618 90.420  136.631 1.00 129.75 ? 159  ASN A C   1 
ATOM 1200 O O   . ASN A 1 159  ? 110.702 89.712  136.224 1.00 129.38 ? 159  ASN A O   1 
ATOM 1201 C CB  . ASN A 1 159  ? 113.770 89.178  137.130 1.00 141.33 ? 159  ASN A CB  1 
ATOM 1202 C CG  . ASN A 1 159  ? 113.270 87.752  137.024 1.00 162.59 ? 159  ASN A CG  1 
ATOM 1203 O OD1 . ASN A 1 159  ? 112.835 87.166  138.014 1.00 179.18 ? 159  ASN A OD1 1 
ATOM 1204 N ND2 . ASN A 1 159  ? 113.333 87.183  135.830 1.00 169.84 ? 159  ASN A ND2 1 
ATOM 1205 N N   . SER A 1 160  ? 111.421 91.454  137.463 1.00 130.81 ? 160  SER A N   1 
ATOM 1206 C CA  . SER A 1 160  ? 110.144 91.649  138.142 1.00 126.90 ? 160  SER A CA  1 
ATOM 1207 C C   . SER A 1 160  ? 109.699 93.112  138.114 1.00 116.08 ? 160  SER A C   1 
ATOM 1208 O O   . SER A 1 160  ? 110.516 94.025  138.057 1.00 111.11 ? 160  SER A O   1 
ATOM 1209 C CB  . SER A 1 160  ? 110.211 91.133  139.557 1.00 129.06 ? 160  SER A CB  1 
ATOM 1210 O OG  . SER A 1 160  ? 111.062 91.942  140.355 1.00 137.72 ? 160  SER A OG  1 
ATOM 1211 N N   . ILE A 1 161  ? 108.379 93.305  138.220 1.00 109.23 ? 161  ILE A N   1 
ATOM 1212 C CA  . ILE A 1 161  ? 107.744 94.599  138.035 1.00 108.27 ? 161  ILE A CA  1 
ATOM 1213 C C   . ILE A 1 161  ? 106.973 94.961  139.304 1.00 115.69 ? 161  ILE A C   1 
ATOM 1214 O O   . ILE A 1 161  ? 106.198 94.150  139.803 1.00 120.17 ? 161  ILE A O   1 
ATOM 1215 C CB  . ILE A 1 161  ? 106.824 94.573  136.797 1.00 113.83 ? 161  ILE A CB  1 
ATOM 1216 C CG1 . ILE A 1 161  ? 106.278 95.965  136.469 1.00 125.99 ? 161  ILE A CG1 1 
ATOM 1217 C CG2 . ILE A 1 161  ? 105.701 93.555  136.958 1.00 111.82 ? 161  ILE A CG2 1 
ATOM 1218 C CD1 . ILE A 1 161  ? 105.504 96.024  135.175 1.00 132.36 ? 161  ILE A CD1 1 
ATOM 1219 N N   . SER A 1 162  ? 107.192 96.190  139.803 1.00 110.99 ? 162  SER A N   1 
ATOM 1220 C CA  . SER A 1 162  ? 106.484 96.744  140.953 1.00 96.52  ? 162  SER A CA  1 
ATOM 1221 C C   . SER A 1 162  ? 105.101 97.228  140.531 1.00 89.87  ? 162  SER A C   1 
ATOM 1222 O O   . SER A 1 162  ? 104.943 97.682  139.402 1.00 99.45  ? 162  SER A O   1 
ATOM 1223 C CB  . SER A 1 162  ? 107.262 97.883  141.539 1.00 92.43  ? 162  SER A CB  1 
ATOM 1224 O OG  . SER A 1 162  ? 107.307 98.966  140.624 1.00 90.49  ? 162  SER A OG  1 
ATOM 1225 N N   . LEU A 1 163  ? 104.120 97.172  141.441 1.00 84.62  ? 163  LEU A N   1 
ATOM 1226 C CA  . LEU A 1 163  ? 102.749 97.510  141.089 1.00 84.63  ? 163  LEU A CA  1 
ATOM 1227 C C   . LEU A 1 163  ? 102.704 98.874  140.408 1.00 90.03  ? 163  LEU A C   1 
ATOM 1228 O O   . LEU A 1 163  ? 102.038 99.020  139.389 1.00 99.97  ? 163  LEU A O   1 
ATOM 1229 C CB  . LEU A 1 163  ? 101.844 97.511  142.322 1.00 86.80  ? 163  LEU A CB  1 
ATOM 1230 C CG  . LEU A 1 163  ? 100.431 98.046  142.085 1.00 89.85  ? 163  LEU A CG  1 
ATOM 1231 C CD1 . LEU A 1 163  ? 99.594  97.067  141.282 1.00 85.29  ? 163  LEU A CD1 1 
ATOM 1232 C CD2 . LEU A 1 163  ? 99.742  98.365  143.400 1.00 101.59 ? 163  LEU A CD2 1 
ATOM 1233 N N   . ARG A 1 164  ? 103.395 99.868  140.972 1.00 94.57  ? 164  ARG A N   1 
ATOM 1234 C CA  . ARG A 1 164  ? 103.452 101.175 140.340 1.00 107.86 ? 164  ARG A CA  1 
ATOM 1235 C C   . ARG A 1 164  ? 103.709 100.991 138.847 1.00 99.97  ? 164  ARG A C   1 
ATOM 1236 O O   . ARG A 1 164  ? 102.921 101.436 138.013 1.00 100.78 ? 164  ARG A O   1 
ATOM 1237 C CB  . ARG A 1 164  ? 104.550 102.050 140.950 1.00 134.86 ? 164  ARG A CB  1 
ATOM 1238 C CG  . ARG A 1 164  ? 104.765 103.363 140.208 1.00 164.73 ? 164  ARG A CG  1 
ATOM 1239 C CD  . ARG A 1 164  ? 106.027 104.090 140.624 1.00 193.80 ? 164  ARG A CD  1 
ATOM 1240 N NE  . ARG A 1 164  ? 106.200 105.324 139.863 1.00 222.26 ? 164  ARG A NE  1 
ATOM 1241 C CZ  . ARG A 1 164  ? 107.293 105.655 139.181 1.00 244.05 ? 164  ARG A CZ  1 
ATOM 1242 N NH1 . ARG A 1 164  ? 108.337 104.845 139.159 1.00 247.15 ? 164  ARG A NH1 1 
ATOM 1243 N NH2 . ARG A 1 164  ? 107.336 106.798 138.516 1.00 250.23 ? 164  ARG A NH2 1 
ATOM 1244 N N   . GLU A 1 165  ? 104.819 100.322 138.523 1.00 91.97  ? 165  GLU A N   1 
ATOM 1245 C CA  . GLU A 1 165  ? 105.216 100.155 137.135 1.00 87.20  ? 165  GLU A CA  1 
ATOM 1246 C C   . GLU A 1 165  ? 104.090 99.461  136.376 1.00 70.93  ? 165  GLU A C   1 
ATOM 1247 O O   . GLU A 1 165  ? 103.685 99.937  135.327 1.00 71.25  ? 165  GLU A O   1 
ATOM 1248 C CB  . GLU A 1 165  ? 106.572 99.454  137.049 1.00 97.97  ? 165  GLU A CB  1 
ATOM 1249 C CG  . GLU A 1 165  ? 107.733 100.400 137.319 1.00 114.09 ? 165  GLU A CG  1 
ATOM 1250 C CD  . GLU A 1 165  ? 108.930 99.815  138.053 1.00 131.11 ? 165  GLU A CD  1 
ATOM 1251 O OE1 . GLU A 1 165  ? 109.919 100.555 138.235 1.00 142.33 ? 165  GLU A OE1 1 
ATOM 1252 O OE2 . GLU A 1 165  ? 108.872 98.636  138.462 1.00 131.22 ? 165  GLU A OE2 1 
ATOM 1253 N N   . LEU A 1 166  ? 103.517 98.393  136.930 1.00 67.48  ? 166  LEU A N   1 
ATOM 1254 C CA  . LEU A 1 166  ? 102.425 97.730  136.242 1.00 69.10  ? 166  LEU A CA  1 
ATOM 1255 C C   . LEU A 1 166  ? 101.368 98.764  135.875 1.00 76.28  ? 166  LEU A C   1 
ATOM 1256 O O   . LEU A 1 166  ? 100.745 98.661  134.821 1.00 94.57  ? 166  LEU A O   1 
ATOM 1257 C CB  . LEU A 1 166  ? 101.821 96.620  137.103 1.00 72.36  ? 166  LEU A CB  1 
ATOM 1258 C CG  . LEU A 1 166  ? 100.567 95.970  136.523 1.00 79.17  ? 166  LEU A CG  1 
ATOM 1259 C CD1 . LEU A 1 166  ? 100.931 94.988  135.420 1.00 83.93  ? 166  LEU A CD1 1 
ATOM 1260 C CD2 . LEU A 1 166  ? 99.757  95.282  137.606 1.00 83.99  ? 166  LEU A CD2 1 
ATOM 1261 N N   . LYS A 1 167  ? 101.181 99.776  136.724 1.00 78.43  ? 167  LYS A N   1 
ATOM 1262 C CA  . LYS A 1 167  ? 100.228 100.823 136.402 1.00 90.93  ? 167  LYS A CA  1 
ATOM 1263 C C   . LYS A 1 167  ? 100.698 101.588 135.164 1.00 80.51  ? 167  LYS A C   1 
ATOM 1264 O O   . LYS A 1 167  ? 99.860  102.001 134.370 1.00 75.26  ? 167  LYS A O   1 
ATOM 1265 C CB  . LYS A 1 167  ? 99.986  101.772 137.581 1.00 111.00 ? 167  LYS A CB  1 
ATOM 1266 C CG  . LYS A 1 167  ? 98.557  102.298 137.698 1.00 119.97 ? 167  LYS A CG  1 
ATOM 1267 C CD  . LYS A 1 167  ? 97.663  101.469 138.596 1.00 119.95 ? 167  LYS A CD  1 
ATOM 1268 C CE  . LYS A 1 167  ? 98.092  101.573 140.046 1.00 128.80 ? 167  LYS A CE  1 
ATOM 1269 N NZ  . LYS A 1 167  ? 97.157  100.892 140.970 1.00 133.64 ? 167  LYS A NZ  1 
ATOM 1270 N N   . THR A 1 168  ? 102.012 101.772 134.978 1.00 75.17  ? 168  THR A N   1 
ATOM 1271 C CA  . THR A 1 168  ? 102.486 102.451 133.777 1.00 80.00  ? 168  THR A CA  1 
ATOM 1272 C C   . THR A 1 168  ? 102.273 101.565 132.544 1.00 75.75  ? 168  THR A C   1 
ATOM 1273 O O   . THR A 1 168  ? 101.863 102.063 131.500 1.00 78.57  ? 168  THR A O   1 
ATOM 1274 C CB  . THR A 1 168  ? 103.941 102.933 133.896 1.00 87.08  ? 168  THR A CB  1 
ATOM 1275 O OG1 . THR A 1 168  ? 104.085 103.996 132.953 1.00 93.43  ? 168  THR A OG1 1 
ATOM 1276 C CG2 . THR A 1 168  ? 104.997 101.883 133.611 1.00 88.51  ? 168  THR A CG2 1 
ATOM 1277 N N   . ILE A 1 169  ? 102.518 100.258 132.682 1.00 67.08  ? 169  ILE A N   1 
ATOM 1278 C CA  . ILE A 1 169  ? 102.448 99.323  131.572 1.00 60.45  ? 169  ILE A CA  1 
ATOM 1279 C C   . ILE A 1 169  ? 101.024 99.122  131.084 1.00 52.42  ? 169  ILE A C   1 
ATOM 1280 O O   . ILE A 1 169  ? 100.837 98.989  129.879 1.00 62.00  ? 169  ILE A O   1 
ATOM 1281 C CB  . ILE A 1 169  ? 103.094 97.972  131.937 1.00 72.02  ? 169  ILE A CB  1 
ATOM 1282 C CG1 . ILE A 1 169  ? 104.622 98.042  131.824 1.00 81.32  ? 169  ILE A CG1 1 
ATOM 1283 C CG2 . ILE A 1 169  ? 102.497 96.829  131.115 1.00 75.10  ? 169  ILE A CG2 1 
ATOM 1284 C CD1 . ILE A 1 169  ? 105.145 99.094  130.855 1.00 86.12  ? 169  ILE A CD1 1 
ATOM 1285 N N   . LEU A 1 170  ? 100.038 99.063  131.979 1.00 53.47  ? 170  LEU A N   1 
ATOM 1286 C CA  . LEU A 1 170  ? 98.711  98.646  131.556 1.00 67.41  ? 170  LEU A CA  1 
ATOM 1287 C C   . LEU A 1 170  ? 98.134  99.623  130.516 1.00 76.59  ? 170  LEU A C   1 
ATOM 1288 O O   . LEU A 1 170  ? 97.456  99.185  129.583 1.00 75.60  ? 170  LEU A O   1 
ATOM 1289 C CB  . LEU A 1 170  ? 97.799  98.487  132.778 1.00 84.90  ? 170  LEU A CB  1 
ATOM 1290 C CG  . LEU A 1 170  ? 96.405  97.932  132.480 1.00 103.83 ? 170  LEU A CG  1 
ATOM 1291 C CD1 . LEU A 1 170  ? 96.478  96.442  132.153 1.00 99.46  ? 170  LEU A CD1 1 
ATOM 1292 C CD2 . LEU A 1 170  ? 95.426  98.203  133.626 1.00 118.63 ? 170  LEU A CD2 1 
ATOM 1293 N N   . PRO A 1 171  ? 98.345  100.964 130.605 1.00 80.24  ? 171  PRO A N   1 
ATOM 1294 C CA  . PRO A 1 171  ? 97.925  101.880 129.542 1.00 74.89  ? 171  PRO A CA  1 
ATOM 1295 C C   . PRO A 1 171  ? 98.582  101.649 128.185 1.00 75.13  ? 171  PRO A C   1 
ATOM 1296 O O   . PRO A 1 171  ? 97.899  101.710 127.167 1.00 87.07  ? 171  PRO A O   1 
ATOM 1297 C CB  . PRO A 1 171  ? 98.324  103.264 130.064 1.00 83.51  ? 171  PRO A CB  1 
ATOM 1298 C CG  . PRO A 1 171  ? 98.315  103.096 131.561 1.00 93.56  ? 171  PRO A CG  1 
ATOM 1299 C CD  . PRO A 1 171  ? 98.836  101.690 131.782 1.00 89.79  ? 171  PRO A CD  1 
ATOM 1300 N N   . LEU A 1 172  ? 99.899  101.400 128.169 1.00 63.92  ? 172  LEU A N   1 
ATOM 1301 C CA  . LEU A 1 172  ? 100.617 101.163 126.929 1.00 58.07  ? 172  LEU A CA  1 
ATOM 1302 C C   . LEU A 1 172  ? 100.079 99.913  126.239 1.00 51.00  ? 172  LEU A C   1 
ATOM 1303 O O   . LEU A 1 172  ? 99.942  99.901  125.018 1.00 51.94  ? 172  LEU A O   1 
ATOM 1304 C CB  . LEU A 1 172  ? 102.115 101.044 127.212 1.00 63.34  ? 172  LEU A CB  1 
ATOM 1305 C CG  . LEU A 1 172  ? 102.774 102.285 127.815 1.00 73.49  ? 172  LEU A CG  1 
ATOM 1306 C CD1 . LEU A 1 172  ? 104.288 102.225 127.644 1.00 81.73  ? 172  LEU A CD1 1 
ATOM 1307 C CD2 . LEU A 1 172  ? 102.223 103.571 127.214 1.00 75.85  ? 172  LEU A CD2 1 
ATOM 1308 N N   . ILE A 1 173  ? 99.770  98.869  127.018 1.00 50.32  ? 173  ILE A N   1 
ATOM 1309 C CA  . ILE A 1 173  ? 99.144  97.685  126.458 1.00 56.06  ? 173  ILE A CA  1 
ATOM 1310 C C   . ILE A 1 173  ? 97.757  98.070  125.955 1.00 56.47  ? 173  ILE A C   1 
ATOM 1311 O O   . ILE A 1 173  ? 97.160  97.313  125.188 1.00 74.27  ? 173  ILE A O   1 
ATOM 1312 C CB  . ILE A 1 173  ? 99.144  96.461  127.410 1.00 69.13  ? 173  ILE A CB  1 
ATOM 1313 C CG1 . ILE A 1 173  ? 98.292  96.636  128.676 1.00 87.72  ? 173  ILE A CG1 1 
ATOM 1314 C CG2 . ILE A 1 173  ? 100.578 96.095  127.769 1.00 72.19  ? 173  ILE A CG2 1 
ATOM 1315 C CD1 . ILE A 1 173  ? 98.294  95.442  129.620 1.00 97.38  ? 173  ILE A CD1 1 
ATOM 1316 N N   . ASN A 1 174  ? 97.283  99.264  126.320 1.00 51.34  ? 174  ASN A N   1 
ATOM 1317 C CA  . ASN A 1 174  ? 96.019  99.766  125.817 1.00 60.20  ? 174  ASN A CA  1 
ATOM 1318 C C   . ASN A 1 174  ? 94.901  99.117  126.626 1.00 60.76  ? 174  ASN A C   1 
ATOM 1319 O O   . ASN A 1 174  ? 93.923  98.661  126.046 1.00 49.40  ? 174  ASN A O   1 
ATOM 1320 C CB  . ASN A 1 174  ? 95.884  99.556  124.299 1.00 67.92  ? 174  ASN A CB  1 
ATOM 1321 C CG  . ASN A 1 174  ? 94.725  100.301 123.657 1.00 81.76  ? 174  ASN A CG  1 
ATOM 1322 O OD1 . ASN A 1 174  ? 93.567  100.050 123.978 1.00 81.36  ? 174  ASN A OD1 1 
ATOM 1323 N ND2 . ASN A 1 174  ? 95.010  101.205 122.731 1.00 87.57  ? 174  ASN A ND2 1 
ATOM 1324 N N   . PHE A 1 175  ? 95.082  99.038  127.953 1.00 70.63  ? 175  PHE A N   1 
ATOM 1325 C CA  . PHE A 1 175  ? 93.995  98.707  128.860 1.00 75.93  ? 175  PHE A CA  1 
ATOM 1326 C C   . PHE A 1 175  ? 93.944  99.783  129.930 1.00 84.65  ? 175  PHE A C   1 
ATOM 1327 O O   . PHE A 1 175  ? 94.986  100.158 130.450 1.00 79.84  ? 175  PHE A O   1 
ATOM 1328 C CB  . PHE A 1 175  ? 94.195  97.363  129.560 1.00 69.93  ? 175  PHE A CB  1 
ATOM 1329 C CG  . PHE A 1 175  ? 93.006  96.839  130.323 1.00 67.98  ? 175  PHE A CG  1 
ATOM 1330 C CD1 . PHE A 1 175  ? 91.767  97.442  130.222 1.00 72.68  ? 175  PHE A CD1 1 
ATOM 1331 C CD2 . PHE A 1 175  ? 93.124  95.721  131.129 1.00 75.08  ? 175  PHE A CD2 1 
ATOM 1332 C CE1 . PHE A 1 175  ? 90.674  96.932  130.901 1.00 81.98  ? 175  PHE A CE1 1 
ATOM 1333 C CE2 . PHE A 1 175  ? 92.036  95.219  131.823 1.00 81.26  ? 175  PHE A CE2 1 
ATOM 1334 C CZ  . PHE A 1 175  ? 90.809  95.823  131.702 1.00 81.05  ? 175  PHE A CZ  1 
ATOM 1335 N N   . LYS A 1 176  ? 92.736  100.264 130.248 1.00 92.20  ? 176  LYS A N   1 
ATOM 1336 C CA  . LYS A 1 176  ? 92.575  101.290 131.261 1.00 96.39  ? 176  LYS A CA  1 
ATOM 1337 C C   . LYS A 1 176  ? 92.145  100.667 132.583 1.00 99.37  ? 176  LYS A C   1 
ATOM 1338 O O   . LYS A 1 176  ? 91.114  99.999  132.645 1.00 98.62  ? 176  LYS A O   1 
ATOM 1339 C CB  . LYS A 1 176  ? 91.533  102.318 130.821 1.00 107.20 ? 176  LYS A CB  1 
ATOM 1340 C CG  . LYS A 1 176  ? 91.261  103.413 131.847 1.00 122.63 ? 176  LYS A CG  1 
ATOM 1341 C CD  . LYS A 1 176  ? 90.159  104.374 131.460 1.00 137.21 ? 176  LYS A CD  1 
ATOM 1342 C CE  . LYS A 1 176  ? 88.787  103.731 131.420 1.00 146.69 ? 176  LYS A CE  1 
ATOM 1343 N NZ  . LYS A 1 176  ? 87.752  104.685 130.952 1.00 150.59 ? 176  LYS A NZ  1 
ATOM 1344 N N   . VAL A 1 177  ? 92.909  100.968 133.644 1.00 100.85 ? 177  VAL A N   1 
ATOM 1345 C CA  . VAL A 1 177  ? 92.662  100.395 134.953 1.00 101.91 ? 177  VAL A CA  1 
ATOM 1346 C C   . VAL A 1 177  ? 91.292  100.894 135.400 1.00 103.80 ? 177  VAL A C   1 
ATOM 1347 O O   . VAL A 1 177  ? 91.060  102.102 135.441 1.00 112.64 ? 177  VAL A O   1 
ATOM 1348 C CB  . VAL A 1 177  ? 93.738  100.772 135.992 1.00 110.90 ? 177  VAL A CB  1 
ATOM 1349 C CG1 . VAL A 1 177  ? 93.772  99.739  137.106 1.00 120.26 ? 177  VAL A CG1 1 
ATOM 1350 C CG2 . VAL A 1 177  ? 95.141  100.963 135.412 1.00 108.81 ? 177  VAL A CG2 1 
ATOM 1351 N N   . SER A 1 178  ? 90.377  99.967  135.696 1.00 106.07 ? 178  SER A N   1 
ATOM 1352 C CA  . SER A 1 178  ? 89.057  100.344 136.174 1.00 116.52 ? 178  SER A CA  1 
ATOM 1353 C C   . SER A 1 178  ? 89.189  101.209 137.425 1.00 134.46 ? 178  SER A C   1 
ATOM 1354 O O   . SER A 1 178  ? 88.507  102.222 137.560 1.00 148.11 ? 178  SER A O   1 
ATOM 1355 C CB  . SER A 1 178  ? 88.201  99.136  136.444 1.00 114.03 ? 178  SER A CB  1 
ATOM 1356 O OG  . SER A 1 178  ? 87.027  99.500  137.157 1.00 107.06 ? 178  SER A OG  1 
ATOM 1357 N N   . SER A 1 179  ? 90.093  100.790 138.319 1.00 143.93 ? 179  SER A N   1 
ATOM 1358 C CA  . SER A 1 179  ? 90.298  101.419 139.613 1.00 149.55 ? 179  SER A CA  1 
ATOM 1359 C C   . SER A 1 179  ? 91.664  101.030 140.167 1.00 150.88 ? 179  SER A C   1 
ATOM 1360 O O   . SER A 1 179  ? 92.242  100.029 139.753 1.00 162.89 ? 179  SER A O   1 
ATOM 1361 C CB  . SER A 1 179  ? 89.210  101.011 140.574 1.00 155.01 ? 179  SER A CB  1 
ATOM 1362 O OG  . SER A 1 179  ? 89.691  101.003 141.910 1.00 154.06 ? 179  SER A OG  1 
ATOM 1363 N N   . ALA A 1 180  ? 92.155  101.805 141.138 1.00 145.60 ? 180  ALA A N   1 
ATOM 1364 C CA  . ALA A 1 180  ? 93.284  101.375 141.946 1.00 139.53 ? 180  ALA A CA  1 
ATOM 1365 C C   . ALA A 1 180  ? 92.965  100.019 142.572 1.00 122.82 ? 180  ALA A C   1 
ATOM 1366 O O   . ALA A 1 180  ? 93.822  99.140  142.633 1.00 121.45 ? 180  ALA A O   1 
ATOM 1367 C CB  . ALA A 1 180  ? 93.597  102.407 143.000 1.00 148.20 ? 180  ALA A CB  1 
ATOM 1368 N N   . LYS A 1 181  ? 91.710  99.857  143.002 1.00 116.10 ? 181  LYS A N   1 
ATOM 1369 C CA  . LYS A 1 181  ? 91.262  98.637  143.649 1.00 124.05 ? 181  LYS A CA  1 
ATOM 1370 C C   . LYS A 1 181  ? 91.457  97.432  142.732 1.00 131.64 ? 181  LYS A C   1 
ATOM 1371 O O   . LYS A 1 181  ? 91.939  96.398  143.186 1.00 145.03 ? 181  LYS A O   1 
ATOM 1372 C CB  . LYS A 1 181  ? 89.797  98.758  144.074 1.00 130.89 ? 181  LYS A CB  1 
ATOM 1373 C CG  . LYS A 1 181  ? 89.302  97.620  144.957 1.00 138.93 ? 181  LYS A CG  1 
ATOM 1374 C CD  . LYS A 1 181  ? 88.680  98.092  146.251 1.00 146.61 ? 181  LYS A CD  1 
ATOM 1375 C CE  . LYS A 1 181  ? 89.694  98.731  147.179 1.00 148.45 ? 181  LYS A CE  1 
ATOM 1376 N NZ  . LYS A 1 181  ? 89.073  99.174  148.449 1.00 152.66 ? 181  LYS A NZ  1 
ATOM 1377 N N   . PHE A 1 182  ? 91.091  97.570  141.452 1.00 129.11 ? 182  PHE A N   1 
ATOM 1378 C CA  . PHE A 1 182  ? 91.061  96.435  140.538 1.00 123.34 ? 182  PHE A CA  1 
ATOM 1379 C C   . PHE A 1 182  ? 92.432  95.768  140.446 1.00 107.00 ? 182  PHE A C   1 
ATOM 1380 O O   . PHE A 1 182  ? 92.518  94.545  140.484 1.00 111.44 ? 182  PHE A O   1 
ATOM 1381 C CB  . PHE A 1 182  ? 90.582  96.859  139.147 1.00 131.38 ? 182  PHE A CB  1 
ATOM 1382 C CG  . PHE A 1 182  ? 90.483  95.746  138.134 1.00 134.20 ? 182  PHE A CG  1 
ATOM 1383 C CD1 . PHE A 1 182  ? 89.546  94.735  138.280 1.00 140.67 ? 182  PHE A CD1 1 
ATOM 1384 C CD2 . PHE A 1 182  ? 91.322  95.716  137.030 1.00 132.13 ? 182  PHE A CD2 1 
ATOM 1385 C CE1 . PHE A 1 182  ? 89.452  93.716  137.345 1.00 142.84 ? 182  PHE A CE1 1 
ATOM 1386 C CE2 . PHE A 1 182  ? 91.229  94.693  136.099 1.00 136.54 ? 182  PHE A CE2 1 
ATOM 1387 C CZ  . PHE A 1 182  ? 90.297  93.695  136.260 1.00 138.54 ? 182  PHE A CZ  1 
ATOM 1388 N N   . LEU A 1 183  ? 93.503  96.559  140.324 1.00 96.27  ? 183  LEU A N   1 
ATOM 1389 C CA  . LEU A 1 183  ? 94.824  95.970  140.194 1.00 99.13  ? 183  LEU A CA  1 
ATOM 1390 C C   . LEU A 1 183  ? 95.180  95.193  141.458 1.00 109.88 ? 183  LEU A C   1 
ATOM 1391 O O   . LEU A 1 183  ? 95.709  94.092  141.355 1.00 123.42 ? 183  LEU A O   1 
ATOM 1392 C CB  . LEU A 1 183  ? 95.874  97.042  139.893 1.00 104.66 ? 183  LEU A CB  1 
ATOM 1393 C CG  . LEU A 1 183  ? 95.953  97.519  138.441 1.00 118.68 ? 183  LEU A CG  1 
ATOM 1394 C CD1 . LEU A 1 183  ? 97.374  97.936  138.077 1.00 122.91 ? 183  LEU A CD1 1 
ATOM 1395 C CD2 . LEU A 1 183  ? 95.449  96.465  137.456 1.00 123.64 ? 183  LEU A CD2 1 
ATOM 1396 N N   . LYS A 1 184  ? 94.858  95.740  142.636 1.00 114.78 ? 184  LYS A N   1 
ATOM 1397 C CA  . LYS A 1 184  ? 95.274  95.131  143.893 1.00 115.90 ? 184  LYS A CA  1 
ATOM 1398 C C   . LYS A 1 184  ? 94.639  93.753  144.075 1.00 109.48 ? 184  LYS A C   1 
ATOM 1399 O O   . LYS A 1 184  ? 95.331  92.805  144.435 1.00 108.79 ? 184  LYS A O   1 
ATOM 1400 C CB  . LYS A 1 184  ? 94.953  96.040  145.086 1.00 124.94 ? 184  LYS A CB  1 
ATOM 1401 C CG  . LYS A 1 184  ? 96.058  97.016  145.478 1.00 136.01 ? 184  LYS A CG  1 
ATOM 1402 C CD  . LYS A 1 184  ? 97.367  96.362  145.911 1.00 143.43 ? 184  LYS A CD  1 
ATOM 1403 C CE  . LYS A 1 184  ? 97.229  95.421  147.092 1.00 148.40 ? 184  LYS A CE  1 
ATOM 1404 N NZ  . LYS A 1 184  ? 98.517  94.775  147.438 1.00 145.43 ? 184  LYS A NZ  1 
ATOM 1405 N N   . ASP A 1 185  ? 93.329  93.640  143.832 1.00 109.28 ? 185  ASP A N   1 
ATOM 1406 C CA  . ASP A 1 185  ? 92.619  92.396  144.090 1.00 118.36 ? 185  ASP A CA  1 
ATOM 1407 C C   . ASP A 1 185  ? 93.213  91.275  143.238 1.00 116.33 ? 185  ASP A C   1 
ATOM 1408 O O   . ASP A 1 185  ? 93.429  90.171  143.734 1.00 118.16 ? 185  ASP A O   1 
ATOM 1409 C CB  . ASP A 1 185  ? 91.112  92.551  143.862 1.00 131.24 ? 185  ASP A CB  1 
ATOM 1410 C CG  . ASP A 1 185  ? 90.285  91.424  144.458 1.00 149.04 ? 185  ASP A CG  1 
ATOM 1411 O OD1 . ASP A 1 185  ? 90.476  90.264  144.035 1.00 159.09 ? 185  ASP A OD1 1 
ATOM 1412 O OD2 . ASP A 1 185  ? 89.458  91.714  145.348 1.00 160.31 ? 185  ASP A OD2 1 
ATOM 1413 N N   . LYS A 1 186  ? 93.493  91.566  141.961 1.00 116.28 ? 186  LYS A N   1 
ATOM 1414 C CA  . LYS A 1 186  ? 94.110  90.585  141.083 1.00 116.25 ? 186  LYS A CA  1 
ATOM 1415 C C   . LYS A 1 186  ? 95.473  90.192  141.651 1.00 123.54 ? 186  LYS A C   1 
ATOM 1416 O O   . LYS A 1 186  ? 95.829  89.017  141.621 1.00 142.10 ? 186  LYS A O   1 
ATOM 1417 C CB  . LYS A 1 186  ? 94.228  91.105  139.644 1.00 110.99 ? 186  LYS A CB  1 
ATOM 1418 C CG  . LYS A 1 186  ? 92.918  91.373  138.913 1.00 105.28 ? 186  LYS A CG  1 
ATOM 1419 C CD  . LYS A 1 186  ? 92.014  90.164  138.741 1.00 107.64 ? 186  LYS A CD  1 
ATOM 1420 C CE  . LYS A 1 186  ? 91.201  89.798  139.968 1.00 114.00 ? 186  LYS A CE  1 
ATOM 1421 N NZ  . LYS A 1 186  ? 90.603  90.977  140.640 1.00 115.49 ? 186  LYS A NZ  1 
ATOM 1422 N N   . PHE A 1 187  ? 96.215  91.165  142.198 1.00 114.60 ? 187  PHE A N   1 
ATOM 1423 C CA  . PHE A 1 187  ? 97.520  90.891  142.784 1.00 111.34 ? 187  PHE A CA  1 
ATOM 1424 C C   . PHE A 1 187  ? 97.435  89.738  143.782 1.00 125.78 ? 187  PHE A C   1 
ATOM 1425 O O   . PHE A 1 187  ? 98.316  88.885  143.799 1.00 133.69 ? 187  PHE A O   1 
ATOM 1426 C CB  . PHE A 1 187  ? 98.110  92.124  143.472 1.00 107.95 ? 187  PHE A CB  1 
ATOM 1427 C CG  . PHE A 1 187  ? 99.235  92.807  142.737 1.00 110.09 ? 187  PHE A CG  1 
ATOM 1428 C CD1 . PHE A 1 187  ? 99.114  93.144  141.400 1.00 116.44 ? 187  PHE A CD1 1 
ATOM 1429 C CD2 . PHE A 1 187  ? 100.404 93.150  143.398 1.00 119.05 ? 187  PHE A CD2 1 
ATOM 1430 C CE1 . PHE A 1 187  ? 100.140 93.803  140.742 1.00 129.95 ? 187  PHE A CE1 1 
ATOM 1431 C CE2 . PHE A 1 187  ? 101.433 93.802  142.736 1.00 126.69 ? 187  PHE A CE2 1 
ATOM 1432 C CZ  . PHE A 1 187  ? 101.297 94.136  141.410 1.00 128.35 ? 187  PHE A CZ  1 
ATOM 1433 N N   . VAL A 1 188  ? 96.375  89.713  144.602 1.00 136.25 ? 188  VAL A N   1 
ATOM 1434 C CA  . VAL A 1 188  ? 96.243  88.723  145.662 1.00 146.27 ? 188  VAL A CA  1 
ATOM 1435 C C   . VAL A 1 188  ? 96.188  87.315  145.070 1.00 145.35 ? 188  VAL A C   1 
ATOM 1436 O O   . VAL A 1 188  ? 96.860  86.418  145.573 1.00 150.62 ? 188  VAL A O   1 
ATOM 1437 C CB  . VAL A 1 188  ? 95.021  89.007  146.563 1.00 157.61 ? 188  VAL A CB  1 
ATOM 1438 C CG1 . VAL A 1 188  ? 94.539  87.764  147.301 1.00 162.01 ? 188  VAL A CG1 1 
ATOM 1439 C CG2 . VAL A 1 188  ? 95.297  90.134  147.548 1.00 162.64 ? 188  VAL A CG2 1 
ATOM 1440 N N   . GLU A 1 189  ? 95.373  87.112  144.026 1.00 138.74 ? 189  GLU A N   1 
ATOM 1441 C CA  . GLU A 1 189  ? 95.190  85.779  143.472 1.00 137.15 ? 189  GLU A CA  1 
ATOM 1442 C C   . GLU A 1 189  ? 96.477  85.333  142.775 1.00 119.63 ? 189  GLU A C   1 
ATOM 1443 O O   . GLU A 1 189  ? 96.830  84.159  142.823 1.00 114.64 ? 189  GLU A O   1 
ATOM 1444 C CB  . GLU A 1 189  ? 93.953  85.713  142.569 1.00 156.57 ? 189  GLU A CB  1 
ATOM 1445 C CG  . GLU A 1 189  ? 94.060  86.503  141.276 1.00 179.49 ? 189  GLU A CG  1 
ATOM 1446 C CD  . GLU A 1 189  ? 92.867  86.376  140.340 1.00 197.08 ? 189  GLU A CD  1 
ATOM 1447 O OE1 . GLU A 1 189  ? 92.951  86.892  139.209 1.00 203.03 ? 189  GLU A OE1 1 
ATOM 1448 O OE2 . GLU A 1 189  ? 91.857  85.762  140.741 1.00 203.47 ? 189  GLU A OE2 1 
ATOM 1449 N N   . ILE A 1 190  ? 97.187  86.275  142.148 1.00 117.37 ? 190  ILE A N   1 
ATOM 1450 C CA  . ILE A 1 190  ? 98.538  86.020  141.670 1.00 123.40 ? 190  ILE A CA  1 
ATOM 1451 C C   . ILE A 1 190  ? 99.398  85.590  142.857 1.00 125.34 ? 190  ILE A C   1 
ATOM 1452 O O   . ILE A 1 190  ? 100.241 84.707  142.718 1.00 133.32 ? 190  ILE A O   1 
ATOM 1453 C CB  . ILE A 1 190  ? 99.115  87.241  140.918 1.00 134.23 ? 190  ILE A CB  1 
ATOM 1454 C CG1 . ILE A 1 190  ? 98.750  87.209  139.431 1.00 140.11 ? 190  ILE A CG1 1 
ATOM 1455 C CG2 . ILE A 1 190  ? 100.623 87.357  141.092 1.00 132.98 ? 190  ILE A CG2 1 
ATOM 1456 C CD1 . ILE A 1 190  ? 97.268  87.313  139.143 1.00 140.25 ? 190  ILE A CD1 1 
ATOM 1457 N N   . GLY A 1 191  ? 99.190  86.230  144.014 1.00 125.76 ? 191  GLY A N   1 
ATOM 1458 C CA  . GLY A 1 191  ? 99.679  85.693  145.273 1.00 130.06 ? 191  GLY A CA  1 
ATOM 1459 C C   . GLY A 1 191  ? 100.996 86.305  145.746 1.00 127.69 ? 191  GLY A C   1 
ATOM 1460 O O   . GLY A 1 191  ? 101.616 85.779  146.666 1.00 138.78 ? 191  GLY A O   1 
ATOM 1461 N N   . ALA A 1 192  ? 101.424 87.411  145.131 1.00 124.32 ? 192  ALA A N   1 
ATOM 1462 C CA  . ALA A 1 192  ? 102.514 88.192  145.689 1.00 135.00 ? 192  ALA A CA  1 
ATOM 1463 C C   . ALA A 1 192  ? 101.926 89.364  146.468 1.00 143.25 ? 192  ALA A C   1 
ATOM 1464 O O   . ALA A 1 192  ? 101.277 90.229  145.890 1.00 141.58 ? 192  ALA A O   1 
ATOM 1465 C CB  . ALA A 1 192  ? 103.451 88.651  144.602 1.00 139.41 ? 192  ALA A CB  1 
ATOM 1466 N N   . HIS A 1 193  ? 102.169 89.376  147.783 1.00 161.74 ? 193  HIS A N   1 
ATOM 1467 C CA  . HIS A 1 193  ? 101.609 90.385  148.672 1.00 181.63 ? 193  HIS A CA  1 
ATOM 1468 C C   . HIS A 1 193  ? 102.619 91.507  148.913 1.00 176.42 ? 193  HIS A C   1 
ATOM 1469 O O   . HIS A 1 193  ? 102.297 92.492  149.574 1.00 177.50 ? 193  HIS A O   1 
ATOM 1470 C CB  . HIS A 1 193  ? 101.095 89.739  149.967 1.00 205.76 ? 193  HIS A CB  1 
ATOM 1471 C CG  . HIS A 1 193  ? 101.787 88.467  150.329 1.00 230.74 ? 193  HIS A CG  1 
ATOM 1472 N ND1 . HIS A 1 193  ? 101.117 87.267  150.436 1.00 241.93 ? 193  HIS A ND1 1 
ATOM 1473 C CD2 . HIS A 1 193  ? 103.074 88.196  150.579 1.00 242.17 ? 193  HIS A CD2 1 
ATOM 1474 C CE1 . HIS A 1 193  ? 101.979 86.312  150.753 1.00 244.77 ? 193  HIS A CE1 1 
ATOM 1475 N NE2 . HIS A 1 193  ? 103.174 86.855  150.842 1.00 245.68 ? 193  HIS A NE2 1 
ATOM 1476 N N   . LYS A 1 194  ? 103.825 91.371  148.348 1.00 177.39 ? 194  LYS A N   1 
ATOM 1477 C CA  . LYS A 1 194  ? 104.890 92.340  148.563 1.00 183.37 ? 194  LYS A CA  1 
ATOM 1478 C C   . LYS A 1 194  ? 104.829 93.440  147.500 1.00 179.70 ? 194  LYS A C   1 
ATOM 1479 O O   . LYS A 1 194  ? 105.654 94.354  147.508 1.00 178.56 ? 194  LYS A O   1 
ATOM 1480 C CB  . LYS A 1 194  ? 106.255 91.638  148.592 1.00 190.64 ? 194  LYS A CB  1 
ATOM 1481 C CG  . LYS A 1 194  ? 106.645 90.854  147.342 1.00 194.23 ? 194  LYS A CG  1 
ATOM 1482 C CD  . LYS A 1 194  ? 107.934 90.067  147.495 1.00 194.71 ? 194  LYS A CD  1 
ATOM 1483 C CE  . LYS A 1 194  ? 109.155 90.939  147.697 1.00 194.98 ? 194  LYS A CE  1 
ATOM 1484 N NZ  . LYS A 1 194  ? 110.394 90.131  147.796 1.00 196.66 ? 194  LYS A NZ  1 
ATOM 1485 N N   . ASP A 1 195  ? 103.834 93.363  146.606 1.00 170.93 ? 195  ASP A N   1 
ATOM 1486 C CA  . ASP A 1 195  ? 103.685 94.312  145.513 1.00 167.05 ? 195  ASP A CA  1 
ATOM 1487 C C   . ASP A 1 195  ? 104.956 94.332  144.663 1.00 156.52 ? 195  ASP A C   1 
ATOM 1488 O O   . ASP A 1 195  ? 105.447 95.396  144.283 1.00 152.80 ? 195  ASP A O   1 
ATOM 1489 C CB  . ASP A 1 195  ? 103.296 95.700  146.031 1.00 176.80 ? 195  ASP A CB  1 
ATOM 1490 C CG  . ASP A 1 195  ? 101.889 95.770  146.602 1.00 187.53 ? 195  ASP A CG  1 
ATOM 1491 O OD1 . ASP A 1 195  ? 101.146 94.773  146.474 1.00 186.56 ? 195  ASP A OD1 1 
ATOM 1492 O OD2 . ASP A 1 195  ? 101.543 96.827  147.167 1.00 197.45 ? 195  ASP A OD2 1 
ATOM 1493 N N   . GLU A 1 196  ? 105.482 93.135  144.383 1.00 147.64 ? 196  GLU A N   1 
ATOM 1494 C CA  . GLU A 1 196  ? 106.578 92.952  143.444 1.00 139.97 ? 196  GLU A CA  1 
ATOM 1495 C C   . GLU A 1 196  ? 106.292 91.698  142.622 1.00 124.43 ? 196  GLU A C   1 
ATOM 1496 O O   . GLU A 1 196  ? 106.892 90.651  142.860 1.00 130.43 ? 196  GLU A O   1 
ATOM 1497 C CB  . GLU A 1 196  ? 107.911 92.820  144.188 1.00 158.01 ? 196  GLU A CB  1 
ATOM 1498 C CG  . GLU A 1 196  ? 109.139 92.885  143.289 1.00 170.07 ? 196  GLU A CG  1 
ATOM 1499 C CD  . GLU A 1 196  ? 109.915 94.189  143.365 1.00 180.86 ? 196  GLU A CD  1 
ATOM 1500 O OE1 . GLU A 1 196  ? 111.144 94.134  143.577 1.00 186.89 ? 196  GLU A OE1 1 
ATOM 1501 O OE2 . GLU A 1 196  ? 109.287 95.258  143.247 1.00 181.93 ? 196  GLU A OE2 1 
ATOM 1502 N N   . LEU A 1 197  ? 105.366 91.803  141.661 1.00 109.50 ? 197  LEU A N   1 
ATOM 1503 C CA  . LEU A 1 197  ? 104.987 90.650  140.859 1.00 107.42 ? 197  LEU A CA  1 
ATOM 1504 C C   . LEU A 1 197  ? 106.214 90.107  140.132 1.00 115.59 ? 197  LEU A C   1 
ATOM 1505 O O   . LEU A 1 197  ? 106.988 90.871  139.569 1.00 115.96 ? 197  LEU A O   1 
ATOM 1506 C CB  . LEU A 1 197  ? 103.880 91.018  139.865 1.00 106.36 ? 197  LEU A CB  1 
ATOM 1507 C CG  . LEU A 1 197  ? 102.475 91.212  140.445 1.00 120.26 ? 197  LEU A CG  1 
ATOM 1508 C CD1 . LEU A 1 197  ? 101.407 90.864  139.417 1.00 123.36 ? 197  LEU A CD1 1 
ATOM 1509 C CD2 . LEU A 1 197  ? 102.255 90.399  141.714 1.00 125.11 ? 197  LEU A CD2 1 
ATOM 1510 N N   . SER A 1 198  ? 106.378 88.778  140.197 1.00 121.17 ? 198  SER A N   1 
ATOM 1511 C CA  . SER A 1 198  ? 107.466 88.050  139.557 1.00 120.67 ? 198  SER A CA  1 
ATOM 1512 C C   . SER A 1 198  ? 107.141 87.828  138.085 1.00 107.84 ? 198  SER A C   1 
ATOM 1513 O O   . SER A 1 198  ? 105.971 87.673  137.750 1.00 105.35 ? 198  SER A O   1 
ATOM 1514 C CB  . SER A 1 198  ? 107.671 86.724  140.241 1.00 127.19 ? 198  SER A CB  1 
ATOM 1515 O OG  . SER A 1 198  ? 106.543 85.880  140.046 1.00 119.97 ? 198  SER A OG  1 
ATOM 1516 N N   . PHE A 1 199  ? 108.161 87.763  137.218 1.00 90.33  ? 199  PHE A N   1 
ATOM 1517 C CA  . PHE A 1 199  ? 107.884 87.568  135.805 1.00 85.15  ? 199  PHE A CA  1 
ATOM 1518 C C   . PHE A 1 199  ? 106.891 86.424  135.653 1.00 79.96  ? 199  PHE A C   1 
ATOM 1519 O O   . PHE A 1 199  ? 105.903 86.561  134.942 1.00 85.41  ? 199  PHE A O   1 
ATOM 1520 C CB  . PHE A 1 199  ? 109.123 87.264  134.959 1.00 90.55  ? 199  PHE A CB  1 
ATOM 1521 C CG  . PHE A 1 199  ? 108.792 86.868  133.537 1.00 91.46  ? 199  PHE A CG  1 
ATOM 1522 C CD1 . PHE A 1 199  ? 108.300 85.606  133.237 1.00 96.80  ? 199  PHE A CD1 1 
ATOM 1523 C CD2 . PHE A 1 199  ? 108.922 87.774  132.499 1.00 87.83  ? 199  PHE A CD2 1 
ATOM 1524 C CE1 . PHE A 1 199  ? 107.974 85.258  131.935 1.00 95.70  ? 199  PHE A CE1 1 
ATOM 1525 C CE2 . PHE A 1 199  ? 108.594 87.425  131.199 1.00 89.68  ? 199  PHE A CE2 1 
ATOM 1526 C CZ  . PHE A 1 199  ? 108.126 86.166  130.917 1.00 92.30  ? 199  PHE A CZ  1 
ATOM 1527 N N   . GLU A 1 200  ? 107.160 85.305  136.327 1.00 83.14  ? 200  GLU A N   1 
ATOM 1528 C CA  . GLU A 1 200  ? 106.317 84.128  136.206 1.00 96.43  ? 200  GLU A CA  1 
ATOM 1529 C C   . GLU A 1 200  ? 104.889 84.501  136.585 1.00 88.95  ? 200  GLU A C   1 
ATOM 1530 O O   . GLU A 1 200  ? 103.940 84.057  135.942 1.00 87.12  ? 200  GLU A O   1 
ATOM 1531 C CB  . GLU A 1 200  ? 106.836 82.984  137.079 1.00 126.80 ? 200  GLU A CB  1 
ATOM 1532 C CG  . GLU A 1 200  ? 108.131 82.363  136.575 1.00 155.92 ? 200  GLU A CG  1 
ATOM 1533 C CD  . GLU A 1 200  ? 109.403 83.122  136.919 1.00 172.72 ? 200  GLU A CD  1 
ATOM 1534 O OE1 . GLU A 1 200  ? 110.318 82.507  137.503 1.00 178.60 ? 200  GLU A OE1 1 
ATOM 1535 O OE2 . GLU A 1 200  ? 109.474 84.328  136.611 1.00 176.19 ? 200  GLU A OE2 1 
ATOM 1536 N N   . GLN A 1 201  ? 104.757 85.337  137.621 1.00 90.96  ? 201  GLN A N   1 
ATOM 1537 C CA  . GLN A 1 201  ? 103.454 85.785  138.082 1.00 94.36  ? 201  GLN A CA  1 
ATOM 1538 C C   . GLN A 1 201  ? 102.815 86.695  137.035 1.00 84.54  ? 201  GLN A C   1 
ATOM 1539 O O   . GLN A 1 201  ? 101.648 86.517  136.701 1.00 74.36  ? 201  GLN A O   1 
ATOM 1540 C CB  . GLN A 1 201  ? 103.575 86.458  139.453 1.00 97.15  ? 201  GLN A CB  1 
ATOM 1541 C CG  . GLN A 1 201  ? 103.612 85.453  140.595 1.00 105.20 ? 201  GLN A CG  1 
ATOM 1542 C CD  . GLN A 1 201  ? 103.981 86.067  141.921 1.00 106.83 ? 201  GLN A CD  1 
ATOM 1543 O OE1 . GLN A 1 201  ? 105.064 86.627  142.079 1.00 99.14  ? 201  GLN A OE1 1 
ATOM 1544 N NE2 . GLN A 1 201  ? 103.093 85.934  142.896 1.00 110.06 ? 201  GLN A NE2 1 
ATOM 1545 N N   . PHE A 1 202  ? 103.580 87.662  136.514 1.00 76.22  ? 202  PHE A N   1 
ATOM 1546 C CA  . PHE A 1 202  ? 103.041 88.582  135.527 1.00 68.18  ? 202  PHE A CA  1 
ATOM 1547 C C   . PHE A 1 202  ? 102.292 87.733  134.514 1.00 58.75  ? 202  PHE A C   1 
ATOM 1548 O O   . PHE A 1 202  ? 101.103 87.929  134.307 1.00 57.97  ? 202  PHE A O   1 
ATOM 1549 C CB  . PHE A 1 202  ? 104.146 89.445  134.907 1.00 74.13  ? 202  PHE A CB  1 
ATOM 1550 C CG  . PHE A 1 202  ? 103.720 90.716  134.214 1.00 79.10  ? 202  PHE A CG  1 
ATOM 1551 C CD1 . PHE A 1 202  ? 102.389 90.994  133.944 1.00 93.00  ? 202  PHE A CD1 1 
ATOM 1552 C CD2 . PHE A 1 202  ? 104.670 91.651  133.838 1.00 79.02  ? 202  PHE A CD2 1 
ATOM 1553 C CE1 . PHE A 1 202  ? 102.027 92.173  133.311 1.00 106.83 ? 202  PHE A CE1 1 
ATOM 1554 C CE2 . PHE A 1 202  ? 104.308 92.825  133.197 1.00 86.78  ? 202  PHE A CE2 1 
ATOM 1555 C CZ  . PHE A 1 202  ? 102.987 93.086  132.936 1.00 103.95 ? 202  PHE A CZ  1 
ATOM 1556 N N   . HIS A 1 203  ? 102.977 86.735  133.960 1.00 64.38  ? 203  HIS A N   1 
ATOM 1557 C CA  . HIS A 1 203  ? 102.339 85.847  133.008 1.00 75.17  ? 203  HIS A CA  1 
ATOM 1558 C C   . HIS A 1 203  ? 101.035 85.340  133.616 1.00 84.02  ? 203  HIS A C   1 
ATOM 1559 O O   . HIS A 1 203  ? 100.020 85.318  132.926 1.00 95.29  ? 203  HIS A O   1 
ATOM 1560 C CB  . HIS A 1 203  ? 103.287 84.743  132.525 1.00 78.68  ? 203  HIS A CB  1 
ATOM 1561 C CG  . HIS A 1 203  ? 102.696 83.897  131.445 1.00 84.47  ? 203  HIS A CG  1 
ATOM 1562 N ND1 . HIS A 1 203  ? 101.467 83.281  131.571 1.00 87.07  ? 203  HIS A ND1 1 
ATOM 1563 C CD2 . HIS A 1 203  ? 103.148 83.579  130.227 1.00 92.68  ? 203  HIS A CD2 1 
ATOM 1564 C CE1 . HIS A 1 203  ? 101.197 82.610  130.463 1.00 95.07  ? 203  HIS A CE1 1 
ATOM 1565 N NE2 . HIS A 1 203  ? 102.205 82.779  129.631 1.00 100.04 ? 203  HIS A NE2 1 
ATOM 1566 N N   . LEU A 1 204  ? 101.033 84.971  134.903 1.00 86.75  ? 204  LEU A N   1 
ATOM 1567 C CA  . LEU A 1 204  ? 99.792  84.510  135.506 1.00 92.73  ? 204  LEU A CA  1 
ATOM 1568 C C   . LEU A 1 204  ? 98.762  85.636  135.485 1.00 86.75  ? 204  LEU A C   1 
ATOM 1569 O O   . LEU A 1 204  ? 97.592  85.378  135.224 1.00 81.06  ? 204  LEU A O   1 
ATOM 1570 C CB  . LEU A 1 204  ? 100.007 83.985  136.928 1.00 105.07 ? 204  LEU A CB  1 
ATOM 1571 C CG  . LEU A 1 204  ? 98.736  83.471  137.612 1.00 120.66 ? 204  LEU A CG  1 
ATOM 1572 C CD1 . LEU A 1 204  ? 98.116  82.306  136.838 1.00 115.35 ? 204  LEU A CD1 1 
ATOM 1573 C CD2 . LEU A 1 204  ? 99.026  83.074  139.056 1.00 137.51 ? 204  LEU A CD2 1 
ATOM 1574 N N   . PHE A 1 205  ? 99.200  86.879  135.715 1.00 82.76  ? 205  PHE A N   1 
ATOM 1575 C CA  . PHE A 1 205  ? 98.297  88.019  135.640 1.00 82.50  ? 205  PHE A CA  1 
ATOM 1576 C C   . PHE A 1 205  ? 97.678  88.098  134.246 1.00 78.24  ? 205  PHE A C   1 
ATOM 1577 O O   . PHE A 1 205  ? 96.465  87.962  134.108 1.00 68.58  ? 205  PHE A O   1 
ATOM 1578 C CB  . PHE A 1 205  ? 99.014  89.323  136.016 1.00 78.82  ? 205  PHE A CB  1 
ATOM 1579 C CG  . PHE A 1 205  ? 98.128  90.524  136.218 1.00 79.98  ? 205  PHE A CG  1 
ATOM 1580 C CD1 . PHE A 1 205  ? 96.787  90.374  136.540 1.00 93.08  ? 205  PHE A CD1 1 
ATOM 1581 C CD2 . PHE A 1 205  ? 98.634  91.803  136.070 1.00 77.19  ? 205  PHE A CD2 1 
ATOM 1582 C CE1 . PHE A 1 205  ? 95.973  91.477  136.733 1.00 100.47 ? 205  PHE A CE1 1 
ATOM 1583 C CE2 . PHE A 1 205  ? 97.813  92.903  136.252 1.00 89.46  ? 205  PHE A CE2 1 
ATOM 1584 C CZ  . PHE A 1 205  ? 96.488  92.742  136.590 1.00 101.64 ? 205  PHE A CZ  1 
ATOM 1585 N N   . TYR A 1 206  ? 98.513  88.326  133.222 1.00 77.26  ? 206  TYR A N   1 
ATOM 1586 C CA  . TYR A 1 206  ? 98.013  88.471  131.867 1.00 69.33  ? 206  TYR A CA  1 
ATOM 1587 C C   . TYR A 1 206  ? 96.998  87.357  131.645 1.00 60.80  ? 206  TYR A C   1 
ATOM 1588 O O   . TYR A 1 206  ? 95.861  87.616  131.287 1.00 68.65  ? 206  TYR A O   1 
ATOM 1589 C CB  . TYR A 1 206  ? 99.158  88.520  130.840 1.00 67.87  ? 206  TYR A CB  1 
ATOM 1590 C CG  . TYR A 1 206  ? 98.730  88.409  129.395 1.00 73.52  ? 206  TYR A CG  1 
ATOM 1591 C CD1 . TYR A 1 206  ? 98.147  87.242  128.931 1.00 90.26  ? 206  TYR A CD1 1 
ATOM 1592 C CD2 . TYR A 1 206  ? 98.917  89.437  128.482 1.00 72.19  ? 206  TYR A CD2 1 
ATOM 1593 C CE1 . TYR A 1 206  ? 97.745  87.097  127.615 1.00 95.50  ? 206  TYR A CE1 1 
ATOM 1594 C CE2 . TYR A 1 206  ? 98.515  89.312  127.160 1.00 82.75  ? 206  TYR A CE2 1 
ATOM 1595 C CZ  . TYR A 1 206  ? 97.933  88.132  126.723 1.00 95.80  ? 206  TYR A CZ  1 
ATOM 1596 O OH  . TYR A 1 206  ? 97.502  87.930  125.431 1.00 109.01 ? 206  TYR A OH  1 
ATOM 1597 N N   . LYS A 1 207  ? 97.401  86.115  131.881 1.00 63.01  ? 207  LYS A N   1 
ATOM 1598 C CA  . LYS A 1 207  ? 96.554  84.991  131.529 1.00 80.05  ? 207  LYS A CA  1 
ATOM 1599 C C   . LYS A 1 207  ? 95.222  85.099  132.272 1.00 84.33  ? 207  LYS A C   1 
ATOM 1600 O O   . LYS A 1 207  ? 94.228  84.538  131.816 1.00 89.52  ? 207  LYS A O   1 
ATOM 1601 C CB  . LYS A 1 207  ? 97.274  83.666  131.806 1.00 104.56 ? 207  LYS A CB  1 
ATOM 1602 C CG  . LYS A 1 207  ? 96.526  82.409  131.374 1.00 123.55 ? 207  LYS A CG  1 
ATOM 1603 C CD  . LYS A 1 207  ? 97.302  81.110  131.579 1.00 137.13 ? 207  LYS A CD  1 
ATOM 1604 C CE  . LYS A 1 207  ? 97.640  80.797  133.024 1.00 143.69 ? 207  LYS A CE  1 
ATOM 1605 N NZ  . LYS A 1 207  ? 96.435  80.741  133.888 1.00 144.10 ? 207  LYS A NZ  1 
ATOM 1606 N N   . LYS A 1 208  ? 95.192  85.816  133.406 1.00 85.14  ? 208  LYS A N   1 
ATOM 1607 C CA  . LYS A 1 208  ? 93.945  86.042  134.124 1.00 95.95  ? 208  LYS A CA  1 
ATOM 1608 C C   . LYS A 1 208  ? 93.182  87.200  133.493 1.00 89.16  ? 208  LYS A C   1 
ATOM 1609 O O   . LYS A 1 208  ? 92.032  87.045  133.089 1.00 76.68  ? 208  LYS A O   1 
ATOM 1610 C CB  . LYS A 1 208  ? 94.174  86.381  135.601 1.00 115.64 ? 208  LYS A CB  1 
ATOM 1611 C CG  . LYS A 1 208  ? 94.825  85.298  136.450 1.00 137.86 ? 208  LYS A CG  1 
ATOM 1612 C CD  . LYS A 1 208  ? 94.022  84.020  136.564 1.00 152.39 ? 208  LYS A CD  1 
ATOM 1613 C CE  . LYS A 1 208  ? 94.665  83.004  137.485 1.00 160.35 ? 208  LYS A CE  1 
ATOM 1614 N NZ  . LYS A 1 208  ? 94.861  83.541  138.853 1.00 159.11 ? 208  LYS A NZ  1 
ATOM 1615 N N   . LEU A 1 209  ? 93.827  88.372  133.455 1.00 88.67  ? 209  LEU A N   1 
ATOM 1616 C CA  . LEU A 1 209  ? 93.164  89.588  133.015 1.00 83.15  ? 209  LEU A CA  1 
ATOM 1617 C C   . LEU A 1 209  ? 92.414  89.260  131.733 1.00 69.32  ? 209  LEU A C   1 
ATOM 1618 O O   . LEU A 1 209  ? 91.201  89.406  131.658 1.00 67.14  ? 209  LEU A O   1 
ATOM 1619 C CB  . LEU A 1 209  ? 94.202  90.702  132.806 1.00 85.91  ? 209  LEU A CB  1 
ATOM 1620 C CG  . LEU A 1 209  ? 93.665  92.131  132.813 1.00 95.88  ? 209  LEU A CG  1 
ATOM 1621 C CD1 . LEU A 1 209  ? 93.026  92.445  134.160 1.00 103.15 ? 209  LEU A CD1 1 
ATOM 1622 C CD2 . LEU A 1 209  ? 94.780  93.113  132.488 1.00 101.09 ? 209  LEU A CD2 1 
ATOM 1623 N N   . MET A 1 210  ? 93.157  88.739  130.757 1.00 68.83  ? 210  MET A N   1 
ATOM 1624 C CA  . MET A 1 210  ? 92.586  88.424  129.468 1.00 68.56  ? 210  MET A CA  1 
ATOM 1625 C C   . MET A 1 210  ? 91.387  87.511  129.685 1.00 71.54  ? 210  MET A C   1 
ATOM 1626 O O   . MET A 1 210  ? 90.342  87.736  129.079 1.00 83.95  ? 210  MET A O   1 
ATOM 1627 C CB  . MET A 1 210  ? 93.599  87.735  128.550 1.00 73.61  ? 210  MET A CB  1 
ATOM 1628 C CG  . MET A 1 210  ? 94.709  88.644  128.026 1.00 78.62  ? 210  MET A CG  1 
ATOM 1629 S SD  . MET A 1 210  ? 94.215  90.178  127.173 1.00 111.38 ? 210  MET A SD  1 
ATOM 1630 C CE  . MET A 1 210  ? 92.608  89.744  126.499 1.00 121.50 ? 210  MET A CE  1 
ATOM 1631 N N   . PHE A 1 211  ? 91.513  86.507  130.563 1.00 69.67  ? 211  PHE A N   1 
ATOM 1632 C CA  . PHE A 1 211  ? 90.411  85.572  130.728 1.00 75.96  ? 211  PHE A CA  1 
ATOM 1633 C C   . PHE A 1 211  ? 89.205  86.290  131.333 1.00 91.13  ? 211  PHE A C   1 
ATOM 1634 O O   . PHE A 1 211  ? 88.075  86.007  130.937 1.00 89.84  ? 211  PHE A O   1 
ATOM 1635 C CB  . PHE A 1 211  ? 90.787  84.330  131.541 1.00 71.47  ? 211  PHE A CB  1 
ATOM 1636 C CG  . PHE A 1 211  ? 89.669  83.318  131.664 1.00 74.05  ? 211  PHE A CG  1 
ATOM 1637 C CD1 . PHE A 1 211  ? 88.529  83.598  132.402 1.00 76.70  ? 211  PHE A CD1 1 
ATOM 1638 C CD2 . PHE A 1 211  ? 89.752  82.078  131.052 1.00 81.89  ? 211  PHE A CD2 1 
ATOM 1639 C CE1 . PHE A 1 211  ? 87.500  82.674  132.511 1.00 83.44  ? 211  PHE A CE1 1 
ATOM 1640 C CE2 . PHE A 1 211  ? 88.725  81.154  131.168 1.00 86.80  ? 211  PHE A CE2 1 
ATOM 1641 C CZ  . PHE A 1 211  ? 87.601  81.450  131.897 1.00 86.27  ? 211  PHE A CZ  1 
ATOM 1642 N N   . GLU A 1 212  ? 89.420  87.215  132.280 1.00 101.50 ? 212  GLU A N   1 
ATOM 1643 C CA  . GLU A 1 212  ? 88.288  87.745  133.020 1.00 110.42 ? 212  GLU A CA  1 
ATOM 1644 C C   . GLU A 1 212  ? 87.407  88.582  132.098 1.00 97.57  ? 212  GLU A C   1 
ATOM 1645 O O   . GLU A 1 212  ? 86.186  88.463  132.154 1.00 105.12 ? 212  GLU A O   1 
ATOM 1646 C CB  . GLU A 1 212  ? 88.711  88.553  134.246 1.00 130.11 ? 212  GLU A CB  1 
ATOM 1647 C CG  . GLU A 1 212  ? 87.532  88.867  135.144 1.00 156.88 ? 212  GLU A CG  1 
ATOM 1648 C CD  . GLU A 1 212  ? 86.528  87.727  135.223 1.00 172.22 ? 212  GLU A CD  1 
ATOM 1649 O OE1 . GLU A 1 212  ? 85.363  87.933  134.829 1.00 169.98 ? 212  GLU A OE1 1 
ATOM 1650 O OE2 . GLU A 1 212  ? 86.928  86.622  135.642 1.00 177.46 ? 212  GLU A OE2 1 
ATOM 1651 N N   . GLN A 1 213  ? 88.034  89.391  131.237 1.00 84.83  ? 213  GLN A N   1 
ATOM 1652 C CA  . GLN A 1 213  ? 87.311  90.317  130.381 1.00 79.66  ? 213  GLN A CA  1 
ATOM 1653 C C   . GLN A 1 213  ? 86.526  89.561  129.308 1.00 76.78  ? 213  GLN A C   1 
ATOM 1654 O O   . GLN A 1 213  ? 85.365  89.883  129.061 1.00 85.50  ? 213  GLN A O   1 
ATOM 1655 C CB  . GLN A 1 213  ? 88.276  91.328  129.756 1.00 80.36  ? 213  GLN A CB  1 
ATOM 1656 C CG  . GLN A 1 213  ? 89.062  92.149  130.774 1.00 87.90  ? 213  GLN A CG  1 
ATOM 1657 C CD  . GLN A 1 213  ? 88.162  92.985  131.647 1.00 110.92 ? 213  GLN A CD  1 
ATOM 1658 O OE1 . GLN A 1 213  ? 87.423  93.845  131.170 1.00 125.72 ? 213  GLN A OE1 1 
ATOM 1659 N NE2 . GLN A 1 213  ? 88.219  92.737  132.945 1.00 126.62 ? 213  GLN A NE2 1 
ATOM 1660 N N   . GLN A 1 214  ? 87.153  88.551  128.688 1.00 68.13  ? 214  GLN A N   1 
ATOM 1661 C CA  . GLN A 1 214  ? 86.606  87.897  127.509 1.00 67.79  ? 214  GLN A CA  1 
ATOM 1662 C C   . GLN A 1 214  ? 85.794  86.646  127.846 1.00 66.02  ? 214  GLN A C   1 
ATOM 1663 O O   . GLN A 1 214  ? 85.286  85.993  126.948 1.00 64.77  ? 214  GLN A O   1 
ATOM 1664 C CB  . GLN A 1 214  ? 87.745  87.508  126.567 1.00 72.80  ? 214  GLN A CB  1 
ATOM 1665 C CG  . GLN A 1 214  ? 88.607  88.678  126.116 1.00 82.02  ? 214  GLN A CG  1 
ATOM 1666 C CD  . GLN A 1 214  ? 89.689  88.253  125.152 1.00 98.19  ? 214  GLN A CD  1 
ATOM 1667 O OE1 . GLN A 1 214  ? 89.939  87.065  124.959 1.00 103.38 ? 214  GLN A OE1 1 
ATOM 1668 N NE2 . GLN A 1 214  ? 90.377  89.226  124.578 1.00 105.40 ? 214  GLN A NE2 1 
ATOM 1669 N N   . LYS A 1 215  ? 85.672  86.302  129.126 1.00 71.43  ? 215  LYS A N   1 
ATOM 1670 C CA  . LYS A 1 215  ? 85.040  85.058  129.541 1.00 87.35  ? 215  LYS A CA  1 
ATOM 1671 C C   . LYS A 1 215  ? 83.704  84.837  128.826 1.00 76.45  ? 215  LYS A C   1 
ATOM 1672 O O   . LYS A 1 215  ? 83.242  83.700  128.706 1.00 79.44  ? 215  LYS A O   1 
ATOM 1673 C CB  . LYS A 1 215  ? 84.864  85.088  131.064 1.00 113.06 ? 215  LYS A CB  1 
ATOM 1674 C CG  . LYS A 1 215  ? 84.180  83.882  131.705 1.00 128.11 ? 215  LYS A CG  1 
ATOM 1675 C CD  . LYS A 1 215  ? 84.059  84.007  133.214 1.00 137.80 ? 215  LYS A CD  1 
ATOM 1676 C CE  . LYS A 1 215  ? 83.386  85.291  133.658 1.00 146.88 ? 215  LYS A CE  1 
ATOM 1677 N NZ  . LYS A 1 215  ? 83.308  85.403  135.133 1.00 152.08 ? 215  LYS A NZ  1 
ATOM 1678 N N   . SER A 1 216  ? 83.090  85.921  128.337 1.00 74.47  ? 216  SER A N   1 
ATOM 1679 C CA  . SER A 1 216  ? 81.756  85.855  127.758 1.00 88.00  ? 216  SER A CA  1 
ATOM 1680 C C   . SER A 1 216  ? 81.722  85.038  126.461 1.00 89.39  ? 216  SER A C   1 
ATOM 1681 O O   . SER A 1 216  ? 80.750  84.326  126.202 1.00 88.64  ? 216  SER A O   1 
ATOM 1682 C CB  . SER A 1 216  ? 81.213  87.241  127.556 1.00 99.70  ? 216  SER A CB  1 
ATOM 1683 O OG  . SER A 1 216  ? 81.078  87.911  128.803 1.00 107.61 ? 216  SER A OG  1 
ATOM 1684 N N   . ILE A 1 217  ? 82.790  85.119  125.659 1.00 79.29  ? 217  ILE A N   1 
ATOM 1685 C CA  . ILE A 1 217  ? 82.856  84.456  124.366 1.00 70.59  ? 217  ILE A CA  1 
ATOM 1686 C C   . ILE A 1 217  ? 82.680  82.948  124.558 1.00 71.18  ? 217  ILE A C   1 
ATOM 1687 O O   . ILE A 1 217  ? 81.986  82.287  123.785 1.00 71.73  ? 217  ILE A O   1 
ATOM 1688 C CB  . ILE A 1 217  ? 84.189  84.814  123.675 1.00 65.83  ? 217  ILE A CB  1 
ATOM 1689 C CG1 . ILE A 1 217  ? 84.390  86.330  123.641 1.00 64.39  ? 217  ILE A CG1 1 
ATOM 1690 C CG2 . ILE A 1 217  ? 84.283  84.210  122.277 1.00 74.12  ? 217  ILE A CG2 1 
ATOM 1691 C CD1 . ILE A 1 217  ? 85.691  86.762  123.039 1.00 64.75  ? 217  ILE A CD1 1 
ATOM 1692 N N   . LEU A 1 218  ? 83.368  82.409  125.571 1.00 72.84  ? 218  LEU A N   1 
ATOM 1693 C CA  . LEU A 1 218  ? 83.347  80.991  125.867 1.00 71.83  ? 218  LEU A CA  1 
ATOM 1694 C C   . LEU A 1 218  ? 81.908  80.565  126.119 1.00 75.74  ? 218  LEU A C   1 
ATOM 1695 O O   . LEU A 1 218  ? 81.513  79.467  125.740 1.00 84.92  ? 218  LEU A O   1 
ATOM 1696 C CB  . LEU A 1 218  ? 84.248  80.744  127.079 1.00 75.25  ? 218  LEU A CB  1 
ATOM 1697 C CG  . LEU A 1 218  ? 85.702  81.189  126.904 1.00 90.04  ? 218  LEU A CG  1 
ATOM 1698 C CD1 . LEU A 1 218  ? 86.571  80.715  128.061 1.00 98.81  ? 218  LEU A CD1 1 
ATOM 1699 C CD2 . LEU A 1 218  ? 86.276  80.711  125.571 1.00 89.20  ? 218  LEU A CD2 1 
ATOM 1700 N N   . ASP A 1 219  ? 81.129  81.465  126.726 1.00 91.21  ? 219  ASP A N   1 
ATOM 1701 C CA  . ASP A 1 219  ? 79.742  81.191  127.066 1.00 121.26 ? 219  ASP A CA  1 
ATOM 1702 C C   . ASP A 1 219  ? 78.944  80.835  125.816 1.00 125.80 ? 219  ASP A C   1 
ATOM 1703 O O   . ASP A 1 219  ? 78.064  79.982  125.893 1.00 134.85 ? 219  ASP A O   1 
ATOM 1704 C CB  . ASP A 1 219  ? 79.099  82.360  127.815 1.00 148.92 ? 219  ASP A CB  1 
ATOM 1705 C CG  . ASP A 1 219  ? 79.834  82.755  129.089 1.00 181.13 ? 219  ASP A CG  1 
ATOM 1706 O OD1 . ASP A 1 219  ? 80.852  82.107  129.416 1.00 193.45 ? 219  ASP A OD1 1 
ATOM 1707 O OD2 . ASP A 1 219  ? 79.393  83.722  129.742 1.00 197.54 ? 219  ASP A OD2 1 
ATOM 1708 N N   . GLU A 1 220  ? 79.264  81.465  124.677 1.00 136.02 ? 220  GLU A N   1 
ATOM 1709 C CA  . GLU A 1 220  ? 78.484  81.313  123.453 1.00 159.03 ? 220  GLU A CA  1 
ATOM 1710 C C   . GLU A 1 220  ? 78.376  79.845  123.029 1.00 136.08 ? 220  GLU A C   1 
ATOM 1711 O O   . GLU A 1 220  ? 77.296  79.405  122.628 1.00 132.80 ? 220  GLU A O   1 
ATOM 1712 C CB  . GLU A 1 220  ? 79.074  82.164  122.321 1.00 182.84 ? 220  GLU A CB  1 
ATOM 1713 C CG  . GLU A 1 220  ? 78.170  82.298  121.098 1.00 195.70 ? 220  GLU A CG  1 
ATOM 1714 C CD  . GLU A 1 220  ? 78.164  81.134  120.118 1.00 206.37 ? 220  GLU A CD  1 
ATOM 1715 O OE1 . GLU A 1 220  ? 77.469  81.238  119.083 1.00 214.77 ? 220  GLU A OE1 1 
ATOM 1716 O OE2 . GLU A 1 220  ? 78.847  80.127  120.386 1.00 209.51 ? 220  GLU A OE2 1 
ATOM 1717 N N   . PHE A 1 221  ? 79.484  79.091  123.097 1.00 116.98 ? 221  PHE A N   1 
ATOM 1718 C CA  . PHE A 1 221  ? 79.468  77.702  122.661 1.00 108.64 ? 221  PHE A CA  1 
ATOM 1719 C C   . PHE A 1 221  ? 78.365  76.931  123.378 1.00 121.70 ? 221  PHE A C   1 
ATOM 1720 O O   . PHE A 1 221  ? 77.681  76.131  122.752 1.00 131.73 ? 221  PHE A O   1 
ATOM 1721 C CB  . PHE A 1 221  ? 80.773  76.961  122.957 1.00 93.72  ? 221  PHE A CB  1 
ATOM 1722 C CG  . PHE A 1 221  ? 82.014  77.549  122.343 1.00 92.51  ? 221  PHE A CG  1 
ATOM 1723 C CD1 . PHE A 1 221  ? 82.164  77.660  120.967 1.00 99.11  ? 221  PHE A CD1 1 
ATOM 1724 C CD2 . PHE A 1 221  ? 83.047  77.974  123.158 1.00 98.17  ? 221  PHE A CD2 1 
ATOM 1725 C CE1 . PHE A 1 221  ? 83.327  78.192  120.429 1.00 105.82 ? 221  PHE A CE1 1 
ATOM 1726 C CE2 . PHE A 1 221  ? 84.207  78.501  122.619 1.00 105.91 ? 221  PHE A CE2 1 
ATOM 1727 C CZ  . PHE A 1 221  ? 84.339  78.609  121.257 1.00 106.68 ? 221  PHE A CZ  1 
ATOM 1728 N N   . LYS A 1 222  ? 78.224  77.178  124.689 1.00 129.89 ? 222  LYS A N   1 
ATOM 1729 C CA  . LYS A 1 222  ? 77.334  76.439  125.575 1.00 135.24 ? 222  LYS A CA  1 
ATOM 1730 C C   . LYS A 1 222  ? 75.879  76.545  125.123 1.00 136.10 ? 222  LYS A C   1 
ATOM 1731 O O   . LYS A 1 222  ? 75.024  77.006  125.871 1.00 131.71 ? 222  LYS A O   1 
ATOM 1732 C CB  . LYS A 1 222  ? 77.460  76.975  127.006 1.00 146.49 ? 222  LYS A CB  1 
ATOM 1733 C CG  . LYS A 1 222  ? 78.857  76.904  127.607 1.00 163.34 ? 222  LYS A CG  1 
ATOM 1734 C CD  . LYS A 1 222  ? 78.992  77.555  128.970 1.00 181.21 ? 222  LYS A CD  1 
ATOM 1735 C CE  . LYS A 1 222  ? 78.133  76.925  130.045 1.00 202.73 ? 222  LYS A CE  1 
ATOM 1736 N NZ  . LYS A 1 222  ? 78.329  77.597  131.352 1.00 211.18 ? 222  LYS A NZ  1 
ATOM 1737 N N   . LYS A 1 223  ? 75.604  76.077  123.906 1.00 168.74 ? 223  LYS A N   1 
ATOM 1738 C CA  . LYS A 1 223  ? 74.255  76.005  123.376 1.00 217.08 ? 223  LYS A CA  1 
ATOM 1739 C C   . LYS A 1 223  ? 73.970  74.520  123.169 1.00 239.78 ? 223  LYS A C   1 
ATOM 1740 O O   . LYS A 1 223  ? 74.865  73.788  122.759 1.00 246.20 ? 223  LYS A O   1 
ATOM 1741 C CB  . LYS A 1 223  ? 74.181  76.861  122.105 1.00 251.18 ? 223  LYS A CB  1 
ATOM 1742 C CG  . LYS A 1 223  ? 72.789  77.086  121.530 1.00 280.65 ? 223  LYS A CG  1 
ATOM 1743 C CD  . LYS A 1 223  ? 72.198  75.856  120.877 1.00 304.62 ? 223  LYS A CD  1 
ATOM 1744 C CE  . LYS A 1 223  ? 70.879  76.115  120.180 1.00 319.52 ? 223  LYS A CE  1 
ATOM 1745 N NZ  . LYS A 1 223  ? 71.025  77.061  119.048 1.00 326.18 ? 223  LYS A NZ  1 
ATOM 1746 N N   . ASP A 1 224  ? 72.749  74.070  123.479 1.00 264.99 ? 224  ASP A N   1 
ATOM 1747 C CA  . ASP A 1 224  ? 72.425  72.651  123.418 1.00 279.29 ? 224  ASP A CA  1 
ATOM 1748 C C   . ASP A 1 224  ? 72.561  72.142  121.981 1.00 273.37 ? 224  ASP A C   1 
ATOM 1749 O O   . ASP A 1 224  ? 72.165  72.829  121.042 1.00 271.22 ? 224  ASP A O   1 
ATOM 1750 C CB  . ASP A 1 224  ? 71.025  72.376  123.973 1.00 295.00 ? 224  ASP A CB  1 
ATOM 1751 C CG  . ASP A 1 224  ? 69.917  73.084  123.212 1.00 312.01 ? 224  ASP A CG  1 
ATOM 1752 O OD1 . ASP A 1 224  ? 69.945  74.330  123.167 1.00 324.80 ? 224  ASP A OD1 1 
ATOM 1753 O OD2 . ASP A 1 224  ? 69.045  72.385  122.663 1.00 322.00 ? 224  ASP A OD2 1 
ATOM 1754 N N   . SER A 1 225  ? 73.144  70.940  121.837 1.00 261.44 ? 225  SER A N   1 
ATOM 1755 C CA  . SER A 1 225  ? 73.272  70.225  120.571 1.00 246.25 ? 225  SER A CA  1 
ATOM 1756 C C   . SER A 1 225  ? 74.444  70.738  119.730 1.00 223.25 ? 225  SER A C   1 
ATOM 1757 O O   . SER A 1 225  ? 74.635  70.281  118.605 1.00 227.37 ? 225  SER A O   1 
ATOM 1758 C CB  . SER A 1 225  ? 71.983  70.236  119.778 1.00 254.69 ? 225  SER A CB  1 
ATOM 1759 O OG  . SER A 1 225  ? 70.920  69.661  120.525 1.00 258.50 ? 225  SER A OG  1 
ATOM 1760 N N   . SER A 1 226  ? 75.254  71.650  120.278 1.00 200.17 ? 226  SER A N   1 
ATOM 1761 C CA  . SER A 1 226  ? 76.495  72.048  119.630 1.00 185.13 ? 226  SER A CA  1 
ATOM 1762 C C   . SER A 1 226  ? 77.450  70.859  119.558 1.00 163.35 ? 226  SER A C   1 
ATOM 1763 O O   . SER A 1 226  ? 78.117  70.670  118.547 1.00 166.08 ? 226  SER A O   1 
ATOM 1764 C CB  . SER A 1 226  ? 77.133  73.202  120.350 1.00 193.55 ? 226  SER A CB  1 
ATOM 1765 O OG  . SER A 1 226  ? 78.363  73.560  119.748 1.00 198.35 ? 226  SER A OG  1 
ATOM 1766 N N   . VAL A 1 227  ? 77.472  70.085  120.653 1.00 144.02 ? 227  VAL A N   1 
ATOM 1767 C CA  . VAL A 1 227  ? 78.317  68.918  120.896 1.00 130.97 ? 227  VAL A CA  1 
ATOM 1768 C C   . VAL A 1 227  ? 79.736  69.336  121.279 1.00 118.00 ? 227  VAL A C   1 
ATOM 1769 O O   . VAL A 1 227  ? 80.539  68.467  121.605 1.00 123.70 ? 227  VAL A O   1 
ATOM 1770 C CB  . VAL A 1 227  ? 78.346  67.849  119.778 1.00 137.46 ? 227  VAL A CB  1 
ATOM 1771 C CG1 . VAL A 1 227  ? 76.961  67.486  119.261 1.00 143.02 ? 227  VAL A CG1 1 
ATOM 1772 C CG2 . VAL A 1 227  ? 79.288  68.185  118.631 1.00 143.16 ? 227  VAL A CG2 1 
ATOM 1773 N N   . PHE A 1 228  ? 80.060  70.634  121.283 1.00 107.71 ? 228  PHE A N   1 
ATOM 1774 C CA  . PHE A 1 228  ? 81.304  71.039  121.913 1.00 106.88 ? 228  PHE A CA  1 
ATOM 1775 C C   . PHE A 1 228  ? 81.178  70.847  123.424 1.00 109.55 ? 228  PHE A C   1 
ATOM 1776 O O   . PHE A 1 228  ? 82.149  70.448  124.064 1.00 114.30 ? 228  PHE A O   1 
ATOM 1777 C CB  . PHE A 1 228  ? 81.705  72.475  121.573 1.00 113.86 ? 228  PHE A CB  1 
ATOM 1778 C CG  . PHE A 1 228  ? 82.982  72.905  122.252 1.00 121.81 ? 228  PHE A CG  1 
ATOM 1779 C CD1 . PHE A 1 228  ? 84.138  72.155  122.105 1.00 112.38 ? 228  PHE A CD1 1 
ATOM 1780 C CD2 . PHE A 1 228  ? 83.024  74.023  123.073 1.00 144.84 ? 228  PHE A CD2 1 
ATOM 1781 C CE1 . PHE A 1 228  ? 85.320  72.541  122.717 1.00 123.23 ? 228  PHE A CE1 1 
ATOM 1782 C CE2 . PHE A 1 228  ? 84.202  74.396  123.703 1.00 143.28 ? 228  PHE A CE2 1 
ATOM 1783 C CZ  . PHE A 1 228  ? 85.347  73.655  123.523 1.00 135.21 ? 228  PHE A CZ  1 
ATOM 1784 N N   . ILE A 1 229  ? 79.972  71.095  123.965 1.00 111.97 ? 229  ILE A N   1 
ATOM 1785 C CA  . ILE A 1 229  ? 79.662  70.951  125.382 1.00 119.59 ? 229  ILE A CA  1 
ATOM 1786 C C   . ILE A 1 229  ? 80.861  71.382  126.227 1.00 106.62 ? 229  ILE A C   1 
ATOM 1787 O O   . ILE A 1 229  ? 81.437  70.587  126.972 1.00 114.39 ? 229  ILE A O   1 
ATOM 1788 C CB  . ILE A 1 229  ? 79.169  69.518  125.698 1.00 155.75 ? 229  ILE A CB  1 
ATOM 1789 C CG1 . ILE A 1 229  ? 78.684  69.376  127.146 1.00 177.88 ? 229  ILE A CG1 1 
ATOM 1790 C CG2 . ILE A 1 229  ? 80.208  68.452  125.346 1.00 164.32 ? 229  ILE A CG2 1 
ATOM 1791 C CD1 . ILE A 1 229  ? 77.539  70.295  127.510 1.00 186.04 ? 229  ILE A CD1 1 
ATOM 1792 N N   . LEU A 1 230  ? 81.203  72.671  126.133 1.00 95.94  ? 230  LEU A N   1 
ATOM 1793 C CA  . LEU A 1 230  ? 82.294  73.248  126.904 1.00 93.93  ? 230  LEU A CA  1 
ATOM 1794 C C   . LEU A 1 230  ? 81.979  73.209  128.398 1.00 102.88 ? 230  LEU A C   1 
ATOM 1795 O O   . LEU A 1 230  ? 80.837  73.413  128.808 1.00 98.98  ? 230  LEU A O   1 
ATOM 1796 C CB  . LEU A 1 230  ? 82.503  74.697  126.462 1.00 94.81  ? 230  LEU A CB  1 
ATOM 1797 C CG  . LEU A 1 230  ? 83.581  75.467  127.224 1.00 96.62  ? 230  LEU A CG  1 
ATOM 1798 C CD1 . LEU A 1 230  ? 84.976  74.982  126.850 1.00 97.32  ? 230  LEU A CD1 1 
ATOM 1799 C CD2 . LEU A 1 230  ? 83.439  76.967  126.985 1.00 100.12 ? 230  LEU A CD2 1 
ATOM 1800 N N   . GLY A 1 231  ? 83.024  73.010  129.211 1.00 122.50 ? 231  GLY A N   1 
ATOM 1801 C CA  . GLY A 1 231  ? 82.892  72.976  130.660 1.00 137.01 ? 231  GLY A CA  1 
ATOM 1802 C C   . GLY A 1 231  ? 82.514  74.341  131.227 1.00 132.50 ? 231  GLY A C   1 
ATOM 1803 O O   . GLY A 1 231  ? 82.386  75.311  130.484 1.00 133.98 ? 231  GLY A O   1 
ATOM 1804 N N   . ASN A 1 232  ? 82.316  74.404  132.547 1.00 126.21 ? 232  ASN A N   1 
ATOM 1805 C CA  . ASN A 1 232  ? 82.014  75.667  133.201 1.00 131.69 ? 232  ASN A CA  1 
ATOM 1806 C C   . ASN A 1 232  ? 83.197  76.608  132.983 1.00 125.80 ? 232  ASN A C   1 
ATOM 1807 O O   . ASN A 1 232  ? 84.343  76.207  133.161 1.00 124.88 ? 232  ASN A O   1 
ATOM 1808 C CB  . ASN A 1 232  ? 81.673  75.476  134.682 1.00 148.61 ? 232  ASN A CB  1 
ATOM 1809 C CG  . ASN A 1 232  ? 82.770  74.802  135.483 1.00 170.94 ? 232  ASN A CG  1 
ATOM 1810 O OD1 . ASN A 1 232  ? 82.566  73.722  136.035 1.00 190.09 ? 232  ASN A OD1 1 
ATOM 1811 N ND2 . ASN A 1 232  ? 83.929  75.434  135.573 1.00 173.52 ? 232  ASN A ND2 1 
ATOM 1812 N N   . THR A 1 233  ? 82.910  77.855  132.589 1.00 118.45 ? 233  THR A N   1 
ATOM 1813 C CA  . THR A 1 233  ? 83.944  78.804  132.202 1.00 116.25 ? 233  THR A CA  1 
ATOM 1814 C C   . THR A 1 233  ? 84.213  79.837  133.293 1.00 107.10 ? 233  THR A C   1 
ATOM 1815 O O   . THR A 1 233  ? 84.631  80.956  132.998 1.00 107.83 ? 233  THR A O   1 
ATOM 1816 C CB  . THR A 1 233  ? 83.524  79.580  130.954 1.00 125.70 ? 233  THR A CB  1 
ATOM 1817 O OG1 . THR A 1 233  ? 82.362  80.319  131.331 1.00 129.38 ? 233  THR A OG1 1 
ATOM 1818 C CG2 . THR A 1 233  ? 83.247  78.690  129.765 1.00 129.83 ? 233  THR A CG2 1 
ATOM 1819 N N   . ASP A 1 234  ? 83.986  79.452  134.550 1.00 102.16 ? 234  ASP A N   1 
ATOM 1820 C CA  . ASP A 1 234  ? 83.923  80.399  135.647 1.00 105.00 ? 234  ASP A CA  1 
ATOM 1821 C C   . ASP A 1 234  ? 85.273  81.086  135.818 1.00 83.87  ? 234  ASP A C   1 
ATOM 1822 O O   . ASP A 1 234  ? 85.331  82.296  136.005 1.00 88.56  ? 234  ASP A O   1 
ATOM 1823 C CB  . ASP A 1 234  ? 83.461  79.720  136.941 1.00 131.63 ? 234  ASP A CB  1 
ATOM 1824 C CG  . ASP A 1 234  ? 83.269  80.689  138.097 1.00 159.70 ? 234  ASP A CG  1 
ATOM 1825 O OD1 . ASP A 1 234  ? 84.262  81.332  138.496 1.00 173.71 ? 234  ASP A OD1 1 
ATOM 1826 O OD2 . ASP A 1 234  ? 82.127  80.797  138.584 1.00 174.54 ? 234  ASP A OD2 1 
ATOM 1827 N N   . ARG A 1 235  ? 86.359  80.317  135.782 1.00 79.13  ? 235  ARG A N   1 
ATOM 1828 C CA  . ARG A 1 235  ? 87.658  80.870  136.119 1.00 92.71  ? 235  ARG A CA  1 
ATOM 1829 C C   . ARG A 1 235  ? 88.752  80.186  135.302 1.00 88.27  ? 235  ARG A C   1 
ATOM 1830 O O   . ARG A 1 235  ? 88.584  79.061  134.838 1.00 90.55  ? 235  ARG A O   1 
ATOM 1831 C CB  . ARG A 1 235  ? 87.898  80.752  137.629 1.00 117.81 ? 235  ARG A CB  1 
ATOM 1832 C CG  . ARG A 1 235  ? 87.858  79.328  138.165 1.00 144.43 ? 235  ARG A CG  1 
ATOM 1833 C CD  . ARG A 1 235  ? 87.933  79.258  139.679 1.00 166.00 ? 235  ARG A CD  1 
ATOM 1834 N NE  . ARG A 1 235  ? 87.742  77.892  140.157 1.00 188.37 ? 235  ARG A NE  1 
ATOM 1835 C CZ  . ARG A 1 235  ? 88.658  77.167  140.794 1.00 215.13 ? 235  ARG A CZ  1 
ATOM 1836 N NH1 . ARG A 1 235  ? 89.856  77.667  141.046 1.00 223.89 ? 235  ARG A NH1 1 
ATOM 1837 N NH2 . ARG A 1 235  ? 88.370  75.935  141.178 1.00 221.10 ? 235  ARG A NH2 1 
ATOM 1838 N N   . PRO A 1 236  ? 89.923  80.839  135.118 1.00 87.48  ? 236  PRO A N   1 
ATOM 1839 C CA  . PRO A 1 236  ? 91.060  80.222  134.439 1.00 82.95  ? 236  PRO A CA  1 
ATOM 1840 C C   . PRO A 1 236  ? 91.461  79.017  135.275 1.00 96.63  ? 236  PRO A C   1 
ATOM 1841 O O   . PRO A 1 236  ? 91.405  79.093  136.499 1.00 106.70 ? 236  PRO A O   1 
ATOM 1842 C CB  . PRO A 1 236  ? 92.181  81.273  134.491 1.00 84.19  ? 236  PRO A CB  1 
ATOM 1843 C CG  . PRO A 1 236  ? 91.457  82.567  134.796 1.00 96.08  ? 236  PRO A CG  1 
ATOM 1844 C CD  . PRO A 1 236  ? 90.257  82.175  135.632 1.00 96.75  ? 236  PRO A CD  1 
ATOM 1845 N N   . ASP A 1 237  ? 91.833  77.914  134.620 1.00 119.41 ? 237  ASP A N   1 
ATOM 1846 C CA  . ASP A 1 237  ? 92.277  76.710  135.311 1.00 142.80 ? 237  ASP A CA  1 
ATOM 1847 C C   . ASP A 1 237  ? 91.076  75.902  135.812 1.00 121.33 ? 237  ASP A C   1 
ATOM 1848 O O   . ASP A 1 237  ? 91.259  74.885  136.476 1.00 130.66 ? 237  ASP A O   1 
ATOM 1849 C CB  . ASP A 1 237  ? 93.266  77.037  136.442 1.00 174.23 ? 237  ASP A CB  1 
ATOM 1850 C CG  . ASP A 1 237  ? 93.870  75.821  137.129 1.00 200.17 ? 237  ASP A CG  1 
ATOM 1851 O OD1 . ASP A 1 237  ? 94.504  75.014  136.432 1.00 206.22 ? 237  ASP A OD1 1 
ATOM 1852 O OD2 . ASP A 1 237  ? 93.692  75.693  138.358 1.00 215.47 ? 237  ASP A OD2 1 
ATOM 1853 N N   . ALA A 1 238  ? 89.853  76.333  135.486 1.00 100.07 ? 238  ALA A N   1 
ATOM 1854 C CA  . ALA A 1 238  ? 88.672  75.552  135.807 1.00 94.47  ? 238  ALA A CA  1 
ATOM 1855 C C   . ALA A 1 238  ? 88.219  74.816  134.554 1.00 92.65  ? 238  ALA A C   1 
ATOM 1856 O O   . ALA A 1 238  ? 88.294  75.372  133.461 1.00 104.00 ? 238  ALA A O   1 
ATOM 1857 C CB  . ALA A 1 238  ? 87.585  76.442  136.334 1.00 103.90 ? 238  ALA A CB  1 
ATOM 1858 N N   . SER A 1 239  ? 87.755  73.574  134.725 1.00 101.70 ? 239  SER A N   1 
ATOM 1859 C CA  . SER A 1 239  ? 87.368  72.711  133.615 1.00 116.26 ? 239  SER A CA  1 
ATOM 1860 C C   . SER A 1 239  ? 88.582  72.456  132.720 1.00 120.04 ? 239  SER A C   1 
ATOM 1861 O O   . SER A 1 239  ? 89.677  72.940  133.004 1.00 114.28 ? 239  SER A O   1 
ATOM 1862 C CB  . SER A 1 239  ? 86.192  73.273  132.830 1.00 114.98 ? 239  SER A CB  1 
ATOM 1863 O OG  . SER A 1 239  ? 85.090  73.539  133.683 1.00 115.78 ? 239  SER A OG  1 
ATOM 1864 N N   . ALA A 1 240  ? 88.385  71.676  131.651 1.00 118.49 ? 240  ALA A N   1 
ATOM 1865 C CA  . ALA A 1 240  ? 89.458  71.392  130.715 1.00 122.31 ? 240  ALA A CA  1 
ATOM 1866 C C   . ALA A 1 240  ? 88.872  70.933  129.384 1.00 124.46 ? 240  ALA A C   1 
ATOM 1867 O O   . ALA A 1 240  ? 87.741  70.451  129.335 1.00 129.04 ? 240  ALA A O   1 
ATOM 1868 C CB  . ALA A 1 240  ? 90.378  70.345  131.297 1.00 131.23 ? 240  ALA A CB  1 
ATOM 1869 N N   . VAL A 1 241  ? 89.646  71.099  128.306 1.00 121.07 ? 241  VAL A N   1 
ATOM 1870 C CA  . VAL A 1 241  ? 89.298  70.490  127.035 1.00 129.93 ? 241  VAL A CA  1 
ATOM 1871 C C   . VAL A 1 241  ? 90.444  69.555  126.661 1.00 134.81 ? 241  VAL A C   1 
ATOM 1872 O O   . VAL A 1 241  ? 91.510  70.016  126.262 1.00 127.71 ? 241  VAL A O   1 
ATOM 1873 C CB  . VAL A 1 241  ? 88.956  71.516  125.929 1.00 140.81 ? 241  VAL A CB  1 
ATOM 1874 C CG1 . VAL A 1 241  ? 87.671  72.273  126.242 1.00 147.52 ? 241  VAL A CG1 1 
ATOM 1875 C CG2 . VAL A 1 241  ? 90.084  72.488  125.620 1.00 139.79 ? 241  VAL A CG2 1 
ATOM 1876 N N   . TYR A 1 242  ? 90.215  68.242  126.849 1.00 138.87 ? 242  TYR A N   1 
ATOM 1877 C CA  . TYR A 1 242  ? 91.218  67.218  126.580 1.00 132.53 ? 242  TYR A CA  1 
ATOM 1878 C C   . TYR A 1 242  ? 91.068  66.720  125.140 1.00 123.77 ? 242  TYR A C   1 
ATOM 1879 O O   . TYR A 1 242  ? 90.064  66.990  124.488 1.00 121.37 ? 242  TYR A O   1 
ATOM 1880 C CB  . TYR A 1 242  ? 91.149  66.017  127.538 1.00 131.54 ? 242  TYR A CB  1 
ATOM 1881 C CG  . TYR A 1 242  ? 90.165  66.079  128.681 1.00 126.60 ? 242  TYR A CG  1 
ATOM 1882 C CD1 . TYR A 1 242  ? 88.818  65.846  128.460 1.00 127.22 ? 242  TYR A CD1 1 
ATOM 1883 C CD2 . TYR A 1 242  ? 90.574  66.311  129.986 1.00 126.30 ? 242  TYR A CD2 1 
ATOM 1884 C CE1 . TYR A 1 242  ? 87.895  65.876  129.492 1.00 132.81 ? 242  TYR A CE1 1 
ATOM 1885 C CE2 . TYR A 1 242  ? 89.664  66.353  131.030 1.00 134.90 ? 242  TYR A CE2 1 
ATOM 1886 C CZ  . TYR A 1 242  ? 88.319  66.130  130.783 1.00 137.75 ? 242  TYR A CZ  1 
ATOM 1887 O OH  . TYR A 1 242  ? 87.394  66.160  131.801 1.00 145.22 ? 242  TYR A OH  1 
ATOM 1888 N N   . LEU A 1 243  ? 92.056  65.932  124.691 1.00 107.38 ? 243  LEU A N   1 
ATOM 1889 C CA  . LEU A 1 243  ? 92.271  65.618  123.284 1.00 97.82  ? 243  LEU A CA  1 
ATOM 1890 C C   . LEU A 1 243  ? 91.001  65.083  122.624 1.00 85.97  ? 243  LEU A C   1 
ATOM 1891 O O   . LEU A 1 243  ? 90.667  65.482  121.514 1.00 91.64  ? 243  LEU A O   1 
ATOM 1892 C CB  . LEU A 1 243  ? 93.406  64.595  123.165 1.00 106.61 ? 243  LEU A CB  1 
ATOM 1893 C CG  . LEU A 1 243  ? 94.404  64.812  122.023 1.00 120.21 ? 243  LEU A CG  1 
ATOM 1894 C CD1 . LEU A 1 243  ? 93.722  65.278  120.745 1.00 123.34 ? 243  LEU A CD1 1 
ATOM 1895 C CD2 . LEU A 1 243  ? 95.500  65.791  122.424 1.00 125.13 ? 243  LEU A CD2 1 
ATOM 1896 N N   . HIS A 1 244  ? 90.302  64.162  123.285 1.00 90.31  ? 244  HIS A N   1 
ATOM 1897 C CA  . HIS A 1 244  ? 89.076  63.631  122.715 1.00 108.19 ? 244  HIS A CA  1 
ATOM 1898 C C   . HIS A 1 244  ? 88.136  64.780  122.361 1.00 98.48  ? 244  HIS A C   1 
ATOM 1899 O O   . HIS A 1 244  ? 87.570  64.798  121.272 1.00 99.12  ? 244  HIS A O   1 
ATOM 1900 C CB  . HIS A 1 244  ? 88.451  62.564  123.625 1.00 137.11 ? 244  HIS A CB  1 
ATOM 1901 C CG  . HIS A 1 244  ? 89.017  61.200  123.385 1.00 165.49 ? 244  HIS A CG  1 
ATOM 1902 N ND1 . HIS A 1 244  ? 88.256  60.133  122.959 1.00 172.50 ? 244  HIS A ND1 1 
ATOM 1903 C CD2 . HIS A 1 244  ? 90.275  60.743  123.481 1.00 178.57 ? 244  HIS A CD2 1 
ATOM 1904 C CE1 . HIS A 1 244  ? 89.035  59.068  122.821 1.00 175.24 ? 244  HIS A CE1 1 
ATOM 1905 N NE2 . HIS A 1 244  ? 90.265  59.416  123.133 1.00 174.67 ? 244  HIS A NE2 1 
ATOM 1906 N N   . ASP A 1 245  ? 88.029  65.767  123.256 1.00 100.49 ? 245  ASP A N   1 
ATOM 1907 C CA  . ASP A 1 245  ? 87.064  66.841  123.081 1.00 108.35 ? 245  ASP A CA  1 
ATOM 1908 C C   . ASP A 1 245  ? 87.544  67.788  121.983 1.00 88.22  ? 245  ASP A C   1 
ATOM 1909 O O   . ASP A 1 245  ? 86.782  68.143  121.086 1.00 83.68  ? 245  ASP A O   1 
ATOM 1910 C CB  . ASP A 1 245  ? 86.807  67.642  124.362 1.00 135.93 ? 245  ASP A CB  1 
ATOM 1911 C CG  . ASP A 1 245  ? 87.290  66.996  125.649 1.00 154.80 ? 245  ASP A CG  1 
ATOM 1912 O OD1 . ASP A 1 245  ? 87.102  65.776  125.817 1.00 170.89 ? 245  ASP A OD1 1 
ATOM 1913 O OD2 . ASP A 1 245  ? 87.856  67.726  126.473 1.00 151.33 ? 245  ASP A OD2 1 
ATOM 1914 N N   . PHE A 1 246  ? 88.803  68.227  122.065 1.00 72.82  ? 246  PHE A N   1 
ATOM 1915 C CA  . PHE A 1 246  ? 89.315  69.145  121.064 1.00 63.40  ? 246  PHE A CA  1 
ATOM 1916 C C   . PHE A 1 246  ? 88.936  68.599  119.697 1.00 63.14  ? 246  PHE A C   1 
ATOM 1917 O O   . PHE A 1 246  ? 88.402  69.325  118.867 1.00 71.47  ? 246  PHE A O   1 
ATOM 1918 C CB  . PHE A 1 246  ? 90.826  69.325  121.185 1.00 59.82  ? 246  PHE A CB  1 
ATOM 1919 C CG  . PHE A 1 246  ? 91.339  70.605  120.597 1.00 60.43  ? 246  PHE A CG  1 
ATOM 1920 C CD1 . PHE A 1 246  ? 91.053  71.813  121.205 1.00 73.65  ? 246  PHE A CD1 1 
ATOM 1921 C CD2 . PHE A 1 246  ? 92.100  70.598  119.446 1.00 66.54  ? 246  PHE A CD2 1 
ATOM 1922 C CE1 . PHE A 1 246  ? 91.539  72.995  120.674 1.00 89.58  ? 246  PHE A CE1 1 
ATOM 1923 C CE2 . PHE A 1 246  ? 92.569  71.782  118.904 1.00 79.38  ? 246  PHE A CE2 1 
ATOM 1924 C CZ  . PHE A 1 246  ? 92.304  72.975  119.534 1.00 87.75  ? 246  PHE A CZ  1 
ATOM 1925 N N   . GLN A 1 247  ? 89.161  67.299  119.492 1.00 65.21  ? 247  GLN A N   1 
ATOM 1926 C CA  . GLN A 1 247  ? 88.821  66.683  118.226 1.00 71.45  ? 247  GLN A CA  1 
ATOM 1927 C C   . GLN A 1 247  ? 87.366  67.000  117.882 1.00 71.82  ? 247  GLN A C   1 
ATOM 1928 O O   . GLN A 1 247  ? 87.096  67.413  116.762 1.00 83.09  ? 247  GLN A O   1 
ATOM 1929 C CB  . GLN A 1 247  ? 89.069  65.176  118.237 1.00 82.22  ? 247  GLN A CB  1 
ATOM 1930 C CG  . GLN A 1 247  ? 88.423  64.456  117.058 1.00 94.04  ? 247  GLN A CG  1 
ATOM 1931 C CD  . GLN A 1 247  ? 88.459  62.951  117.193 1.00 101.71 ? 247  GLN A CD  1 
ATOM 1932 O OE1 . GLN A 1 247  ? 87.427  62.297  117.347 1.00 102.50 ? 247  GLN A OE1 1 
ATOM 1933 N NE2 . GLN A 1 247  ? 89.655  62.388  117.131 1.00 100.82 ? 247  GLN A NE2 1 
ATOM 1934 N N   . ARG A 1 248  ? 86.429  66.819  118.819 1.00 71.99  ? 248  ARG A N   1 
ATOM 1935 C CA  . ARG A 1 248  ? 85.020  66.943  118.463 1.00 80.39  ? 248  ARG A CA  1 
ATOM 1936 C C   . ARG A 1 248  ? 84.676  68.402  118.133 1.00 76.47  ? 248  ARG A C   1 
ATOM 1937 O O   . ARG A 1 248  ? 83.818  68.637  117.282 1.00 81.38  ? 248  ARG A O   1 
ATOM 1938 C CB  . ARG A 1 248  ? 84.084  66.245  119.464 1.00 102.10 ? 248  ARG A CB  1 
ATOM 1939 C CG  . ARG A 1 248  ? 84.238  66.609  120.935 1.00 128.09 ? 248  ARG A CG  1 
ATOM 1940 C CD  . ARG A 1 248  ? 83.579  65.597  121.864 1.00 144.68 ? 248  ARG A CD  1 
ATOM 1941 N NE  . ARG A 1 248  ? 82.137  65.466  121.680 1.00 170.49 ? 248  ARG A NE  1 
ATOM 1942 C CZ  . ARG A 1 248  ? 81.227  65.610  122.641 1.00 197.42 ? 248  ARG A CZ  1 
ATOM 1943 N NH1 . ARG A 1 248  ? 81.589  65.974  123.861 1.00 204.00 ? 248  ARG A NH1 1 
ATOM 1944 N NH2 . ARG A 1 248  ? 79.949  65.403  122.370 1.00 201.26 ? 248  ARG A NH2 1 
ATOM 1945 N N   . PHE A 1 249  ? 85.373  69.385  118.728 1.00 74.97  ? 249  PHE A N   1 
ATOM 1946 C CA  . PHE A 1 249  ? 85.234  70.777  118.298 1.00 72.18  ? 249  PHE A CA  1 
ATOM 1947 C C   . PHE A 1 249  ? 85.845  70.934  116.906 1.00 63.29  ? 249  PHE A C   1 
ATOM 1948 O O   . PHE A 1 249  ? 85.182  71.418  115.997 1.00 70.84  ? 249  PHE A O   1 
ATOM 1949 C CB  . PHE A 1 249  ? 85.750  71.746  119.372 1.00 68.96  ? 249  PHE A CB  1 
ATOM 1950 C CG  . PHE A 1 249  ? 86.467  73.001  118.937 1.00 58.74  ? 249  PHE A CG  1 
ATOM 1951 C CD1 . PHE A 1 249  ? 87.833  72.984  118.735 1.00 59.50  ? 249  PHE A CD1 1 
ATOM 1952 C CD2 . PHE A 1 249  ? 85.800  74.206  118.795 1.00 57.12  ? 249  PHE A CD2 1 
ATOM 1953 C CE1 . PHE A 1 249  ? 88.519  74.136  118.382 1.00 58.93  ? 249  PHE A CE1 1 
ATOM 1954 C CE2 . PHE A 1 249  ? 86.482  75.355  118.420 1.00 58.04  ? 249  PHE A CE2 1 
ATOM 1955 C CZ  . PHE A 1 249  ? 87.844  75.321  118.226 1.00 55.97  ? 249  PHE A CZ  1 
ATOM 1956 N N   . LEU A 1 250  ? 87.061  70.439  116.699 1.00 54.96  ? 250  LEU A N   1 
ATOM 1957 C CA  . LEU A 1 250  ? 87.663  70.601  115.390 1.00 54.66  ? 250  LEU A CA  1 
ATOM 1958 C C   . LEU A 1 250  ? 86.795  69.928  114.322 1.00 64.28  ? 250  LEU A C   1 
ATOM 1959 O O   . LEU A 1 250  ? 86.773  70.410  113.193 1.00 79.00  ? 250  LEU A O   1 
ATOM 1960 C CB  . LEU A 1 250  ? 89.102  70.079  115.390 1.00 53.24  ? 250  LEU A CB  1 
ATOM 1961 C CG  . LEU A 1 250  ? 90.133  70.981  116.065 1.00 57.56  ? 250  LEU A CG  1 
ATOM 1962 C CD1 . LEU A 1 250  ? 91.556  70.576  115.674 1.00 62.73  ? 250  LEU A CD1 1 
ATOM 1963 C CD2 . LEU A 1 250  ? 89.877  72.446  115.729 1.00 63.44  ? 250  LEU A CD2 1 
ATOM 1964 N N   . ILE A 1 251  ? 86.026  68.876  114.656 1.00 67.63  ? 251  ILE A N   1 
ATOM 1965 C CA  . ILE A 1 251  ? 85.240  68.195  113.636 1.00 76.00  ? 251  ILE A CA  1 
ATOM 1966 C C   . ILE A 1 251  ? 83.890  68.872  113.413 1.00 71.51  ? 251  ILE A C   1 
ATOM 1967 O O   . ILE A 1 251  ? 83.425  68.865  112.276 1.00 82.38  ? 251  ILE A O   1 
ATOM 1968 C CB  . ILE A 1 251  ? 85.061  66.685  113.895 1.00 99.89  ? 251  ILE A CB  1 
ATOM 1969 C CG1 . ILE A 1 251  ? 84.636  65.952  112.619 1.00 119.49 ? 251  ILE A CG1 1 
ATOM 1970 C CG2 . ILE A 1 251  ? 84.085  66.407  115.028 1.00 104.69 ? 251  ILE A CG2 1 
ATOM 1971 C CD1 . ILE A 1 251  ? 85.632  66.059  111.481 1.00 130.59 ? 251  ILE A CD1 1 
ATOM 1972 N N   . HIS A 1 252  ? 83.231  69.418  114.446 1.00 73.15  ? 252  HIS A N   1 
ATOM 1973 C CA  . HIS A 1 252  ? 81.868  69.909  114.251 1.00 87.07  ? 252  HIS A CA  1 
ATOM 1974 C C   . HIS A 1 252  ? 81.746  71.437  114.204 1.00 86.77  ? 252  HIS A C   1 
ATOM 1975 O O   . HIS A 1 252  ? 81.322  71.970  113.183 1.00 88.72  ? 252  HIS A O   1 
ATOM 1976 C CB  . HIS A 1 252  ? 80.886  69.281  115.242 1.00 97.42  ? 252  HIS A CB  1 
ATOM 1977 C CG  . HIS A 1 252  ? 80.633  67.831  114.984 1.00 111.02 ? 252  HIS A CG  1 
ATOM 1978 N ND1 . HIS A 1 252  ? 79.723  67.096  115.713 1.00 124.09 ? 252  HIS A ND1 1 
ATOM 1979 C CD2 . HIS A 1 252  ? 81.146  66.985  114.077 1.00 114.33 ? 252  HIS A CD2 1 
ATOM 1980 C CE1 . HIS A 1 252  ? 79.710  65.848  115.263 1.00 129.80 ? 252  HIS A CE1 1 
ATOM 1981 N NE2 . HIS A 1 252  ? 80.578  65.756  114.276 1.00 123.11 ? 252  HIS A NE2 1 
ATOM 1982 N N   . GLU A 1 253  ? 82.010  72.146  115.307 1.00 91.91  ? 253  GLU A N   1 
ATOM 1983 C CA  . GLU A 1 253  ? 81.830  73.591  115.298 1.00 101.13 ? 253  GLU A CA  1 
ATOM 1984 C C   . GLU A 1 253  ? 82.623  74.190  114.142 1.00 83.16  ? 253  GLU A C   1 
ATOM 1985 O O   . GLU A 1 253  ? 82.032  74.628  113.159 1.00 88.96  ? 253  GLU A O   1 
ATOM 1986 C CB  . GLU A 1 253  ? 82.222  74.222  116.634 1.00 124.44 ? 253  GLU A CB  1 
ATOM 1987 C CG  . GLU A 1 253  ? 81.248  73.911  117.748 1.00 145.82 ? 253  GLU A CG  1 
ATOM 1988 C CD  . GLU A 1 253  ? 79.817  74.366  117.505 1.00 157.90 ? 253  GLU A CD  1 
ATOM 1989 O OE1 . GLU A 1 253  ? 79.176  73.834  116.581 1.00 159.30 ? 253  GLU A OE1 1 
ATOM 1990 O OE2 . GLU A 1 253  ? 79.345  75.252  118.246 1.00 163.99 ? 253  GLU A OE2 1 
ATOM 1991 N N   . GLN A 1 254  ? 83.950  74.200  114.264 1.00 68.32  ? 254  GLN A N   1 
ATOM 1992 C CA  . GLN A 1 254  ? 84.801  74.506  113.130 1.00 67.06  ? 254  GLN A CA  1 
ATOM 1993 C C   . GLN A 1 254  ? 84.837  73.254  112.275 1.00 78.58  ? 254  GLN A C   1 
ATOM 1994 O O   . GLN A 1 254  ? 84.590  72.183  112.796 1.00 82.94  ? 254  GLN A O   1 
ATOM 1995 C CB  . GLN A 1 254  ? 86.217  74.855  113.570 1.00 63.53  ? 254  GLN A CB  1 
ATOM 1996 C CG  . GLN A 1 254  ? 86.275  76.002  114.563 1.00 73.90  ? 254  GLN A CG  1 
ATOM 1997 C CD  . GLN A 1 254  ? 87.705  76.269  114.957 1.00 85.66  ? 254  GLN A CD  1 
ATOM 1998 O OE1 . GLN A 1 254  ? 88.635  75.645  114.449 1.00 80.77  ? 254  GLN A OE1 1 
ATOM 1999 N NE2 . GLN A 1 254  ? 87.895  77.218  115.861 1.00 96.73  ? 254  GLN A NE2 1 
ATOM 2000 N N   . GLN A 1 255  ? 85.139  73.365  110.983 1.00 95.27  ? 255  GLN A N   1 
ATOM 2001 C CA  . GLN A 1 255  ? 85.270  72.165  110.170 1.00 101.19 ? 255  GLN A CA  1 
ATOM 2002 C C   . GLN A 1 255  ? 86.680  72.145  109.598 1.00 100.61 ? 255  GLN A C   1 
ATOM 2003 O O   . GLN A 1 255  ? 87.125  73.124  109.002 1.00 111.65 ? 255  GLN A O   1 
ATOM 2004 C CB  . GLN A 1 255  ? 84.186  72.115  109.092 1.00 109.64 ? 255  GLN A CB  1 
ATOM 2005 C CG  . GLN A 1 255  ? 82.775  72.064  109.659 1.00 115.32 ? 255  GLN A CG  1 
ATOM 2006 C CD  . GLN A 1 255  ? 81.708  72.340  108.628 1.00 126.39 ? 255  GLN A CD  1 
ATOM 2007 O OE1 . GLN A 1 255  ? 81.983  72.489  107.439 1.00 132.70 ? 255  GLN A OE1 1 
ATOM 2008 N NE2 . GLN A 1 255  ? 80.467  72.414  109.083 1.00 129.37 ? 255  GLN A NE2 1 
ATOM 2009 N N   . GLU A 1 256  ? 87.382  71.034  109.816 1.00 95.45  ? 256  GLU A N   1 
ATOM 2010 C CA  . GLU A 1 256  ? 88.738  70.886  109.327 1.00 107.21 ? 256  GLU A CA  1 
ATOM 2011 C C   . GLU A 1 256  ? 89.072  69.401  109.384 1.00 125.25 ? 256  GLU A C   1 
ATOM 2012 O O   . GLU A 1 256  ? 89.601  68.914  110.379 1.00 140.97 ? 256  GLU A O   1 
ATOM 2013 C CB  . GLU A 1 256  ? 89.677  71.771  110.150 1.00 114.43 ? 256  GLU A CB  1 
ATOM 2014 C CG  . GLU A 1 256  ? 91.043  71.995  109.518 1.00 136.39 ? 256  GLU A CG  1 
ATOM 2015 C CD  . GLU A 1 256  ? 91.923  72.947  110.316 1.00 162.32 ? 256  GLU A CD  1 
ATOM 2016 O OE1 . GLU A 1 256  ? 91.525  74.111  110.484 1.00 170.15 ? 256  GLU A OE1 1 
ATOM 2017 O OE2 . GLU A 1 256  ? 93.001  72.532  110.780 1.00 174.31 ? 256  GLU A OE2 1 
ATOM 2018 N N   . HIS A 1 257  ? 88.721  68.679  108.314 1.00 129.11 ? 257  HIS A N   1 
ATOM 2019 C CA  . HIS A 1 257  ? 88.909  67.239  108.274 1.00 120.97 ? 257  HIS A CA  1 
ATOM 2020 C C   . HIS A 1 257  ? 90.393  66.913  108.409 1.00 107.45 ? 257  HIS A C   1 
ATOM 2021 O O   . HIS A 1 257  ? 90.765  65.744  108.401 1.00 106.49 ? 257  HIS A O   1 
ATOM 2022 C CB  . HIS A 1 257  ? 88.248  66.640  107.027 1.00 132.46 ? 257  HIS A CB  1 
ATOM 2023 C CG  . HIS A 1 257  ? 86.758  66.693  107.074 1.00 152.89 ? 257  HIS A CG  1 
ATOM 2024 N ND1 . HIS A 1 257  ? 86.080  67.228  108.148 1.00 167.18 ? 257  HIS A ND1 1 
ATOM 2025 C CD2 . HIS A 1 257  ? 85.820  66.286  106.209 1.00 168.76 ? 257  HIS A CD2 1 
ATOM 2026 C CE1 . HIS A 1 257  ? 84.777  67.143  107.930 1.00 175.36 ? 257  HIS A CE1 1 
ATOM 2027 N NE2 . HIS A 1 257  ? 84.595  66.574  106.757 1.00 177.16 ? 257  HIS A NE2 1 
ATOM 2028 N N   . TRP A 1 258  ? 91.241  67.933  108.594 1.00 99.47  ? 258  TRP A N   1 
ATOM 2029 C CA  . TRP A 1 258  ? 92.634  67.654  108.871 1.00 93.15  ? 258  TRP A CA  1 
ATOM 2030 C C   . TRP A 1 258  ? 92.727  66.722  110.067 1.00 86.82  ? 258  TRP A C   1 
ATOM 2031 O O   . TRP A 1 258  ? 93.664  65.948  110.169 1.00 97.28  ? 258  TRP A O   1 
ATOM 2032 C CB  . TRP A 1 258  ? 93.427  68.932  109.109 1.00 93.15  ? 258  TRP A CB  1 
ATOM 2033 C CG  . TRP A 1 258  ? 93.352  69.436  110.512 1.00 100.32 ? 258  TRP A CG  1 
ATOM 2034 C CD1 . TRP A 1 258  ? 92.241  69.789  111.215 1.00 114.32 ? 258  TRP A CD1 1 
ATOM 2035 C CD2 . TRP A 1 258  ? 94.463  69.683  111.382 1.00 115.76 ? 258  TRP A CD2 1 
ATOM 2036 N NE1 . TRP A 1 258  ? 92.581  70.234  112.462 1.00 121.66 ? 258  TRP A NE1 1 
ATOM 2037 C CE2 . TRP A 1 258  ? 93.940  70.181  112.596 1.00 121.83 ? 258  TRP A CE2 1 
ATOM 2038 C CE3 . TRP A 1 258  ? 95.848  69.552  111.243 1.00 138.86 ? 258  TRP A CE3 1 
ATOM 2039 C CZ2 . TRP A 1 258  ? 94.753  70.523  113.674 1.00 132.16 ? 258  TRP A CZ2 1 
ATOM 2040 C CZ3 . TRP A 1 258  ? 96.653  69.902  112.303 1.00 148.99 ? 258  TRP A CZ3 1 
ATOM 2041 C CH2 . TRP A 1 258  ? 96.111  70.383  113.495 1.00 144.42 ? 258  TRP A CH2 1 
ATOM 2042 N N   . ALA A 1 259  ? 91.748  66.799  110.964 1.00 85.16  ? 259  ALA A N   1 
ATOM 2043 C CA  . ALA A 1 259  ? 91.739  65.923  112.115 1.00 90.82  ? 259  ALA A CA  1 
ATOM 2044 C C   . ALA A 1 259  ? 90.407  65.183  112.217 1.00 90.56  ? 259  ALA A C   1 
ATOM 2045 O O   . ALA A 1 259  ? 89.631  65.392  113.146 1.00 94.17  ? 259  ALA A O   1 
ATOM 2046 C CB  . ALA A 1 259  ? 92.048  66.714  113.356 1.00 96.83  ? 259  ALA A CB  1 
ATOM 2047 N N   . GLN A 1 260  ? 90.162  64.293  111.255 1.00 92.04  ? 260  GLN A N   1 
ATOM 2048 C CA  . GLN A 1 260  ? 89.302  63.149  111.501 1.00 100.12 ? 260  GLN A CA  1 
ATOM 2049 C C   . GLN A 1 260  ? 90.137  62.085  112.211 1.00 100.10 ? 260  GLN A C   1 
ATOM 2050 O O   . GLN A 1 260  ? 89.596  61.118  112.742 1.00 91.39  ? 260  GLN A O   1 
ATOM 2051 C CB  . GLN A 1 260  ? 88.699  62.618  110.199 1.00 113.67 ? 260  GLN A CB  1 
ATOM 2052 C CG  . GLN A 1 260  ? 87.778  61.421  110.400 1.00 129.11 ? 260  GLN A CG  1 
ATOM 2053 C CD  . GLN A 1 260  ? 86.731  61.663  111.461 1.00 137.49 ? 260  GLN A CD  1 
ATOM 2054 O OE1 . GLN A 1 260  ? 86.734  61.040  112.521 1.00 138.88 ? 260  GLN A OE1 1 
ATOM 2055 N NE2 . GLN A 1 260  ? 85.829  62.591  111.187 1.00 139.97 ? 260  GLN A NE2 1 
ATOM 2056 N N   . ASP A 1 261  ? 91.462  62.302  112.218 1.00 117.23 ? 261  ASP A N   1 
ATOM 2057 C CA  . ASP A 1 261  ? 92.441  61.393  112.795 1.00 136.74 ? 261  ASP A CA  1 
ATOM 2058 C C   . ASP A 1 261  ? 92.996  61.946  114.107 1.00 126.09 ? 261  ASP A C   1 
ATOM 2059 O O   . ASP A 1 261  ? 93.590  63.020  114.133 1.00 119.19 ? 261  ASP A O   1 
ATOM 2060 C CB  . ASP A 1 261  ? 93.610  61.168  111.836 1.00 153.85 ? 261  ASP A CB  1 
ATOM 2061 C CG  . ASP A 1 261  ? 94.950  61.096  112.552 1.00 165.74 ? 261  ASP A CG  1 
ATOM 2062 O OD1 . ASP A 1 261  ? 95.143  60.167  113.363 1.00 177.89 ? 261  ASP A OD1 1 
ATOM 2063 O OD2 . ASP A 1 261  ? 95.768  62.002  112.335 1.00 162.07 ? 261  ASP A OD2 1 
ATOM 2064 N N   . LEU A 1 262  ? 92.879  61.150  115.175 1.00 115.28 ? 262  LEU A N   1 
ATOM 2065 C CA  . LEU A 1 262  ? 93.221  61.606  116.507 1.00 108.35 ? 262  LEU A CA  1 
ATOM 2066 C C   . LEU A 1 262  ? 94.694  61.992  116.559 1.00 97.83  ? 262  LEU A C   1 
ATOM 2067 O O   . LEU A 1 262  ? 95.039  63.007  117.155 1.00 103.61 ? 262  LEU A O   1 
ATOM 2068 C CB  . LEU A 1 262  ? 92.885  60.507  117.520 1.00 124.20 ? 262  LEU A CB  1 
ATOM 2069 C CG  . LEU A 1 262  ? 93.018  60.902  118.991 1.00 145.05 ? 262  LEU A CG  1 
ATOM 2070 C CD1 . LEU A 1 262  ? 92.063  62.033  119.342 1.00 145.46 ? 262  LEU A CD1 1 
ATOM 2071 C CD2 . LEU A 1 262  ? 92.772  59.706  119.901 1.00 159.31 ? 262  LEU A CD2 1 
ATOM 2072 N N   . ASN A 1 263  ? 95.562  61.204  115.920 1.00 99.09  ? 263  ASN A N   1 
ATOM 2073 C CA  . ASN A 1 263  ? 96.987  61.408  116.101 1.00 114.42 ? 263  ASN A CA  1 
ATOM 2074 C C   . ASN A 1 263  ? 97.374  62.829  115.704 1.00 115.25 ? 263  ASN A C   1 
ATOM 2075 O O   . ASN A 1 263  ? 98.187  63.444  116.387 1.00 126.46 ? 263  ASN A O   1 
ATOM 2076 C CB  . ASN A 1 263  ? 97.860  60.393  115.360 1.00 135.11 ? 263  ASN A CB  1 
ATOM 2077 C CG  . ASN A 1 263  ? 99.336  60.616  115.626 1.00 147.74 ? 263  ASN A CG  1 
ATOM 2078 O OD1 . ASN A 1 263  ? 100.095 60.941  114.715 1.00 156.45 ? 263  ASN A OD1 1 
ATOM 2079 N ND2 . ASN A 1 263  ? 99.746  60.477  116.877 1.00 149.26 ? 263  ASN A ND2 1 
ATOM 2080 N N   . LYS A 1 264  ? 96.810  63.378  114.626 1.00 114.83 ? 264  LYS A N   1 
ATOM 2081 C CA  . LYS A 1 264  ? 97.235  64.718  114.251 1.00 119.94 ? 264  LYS A CA  1 
ATOM 2082 C C   . LYS A 1 264  ? 96.627  65.750  115.203 1.00 104.54 ? 264  LYS A C   1 
ATOM 2083 O O   . LYS A 1 264  ? 97.266  66.763  115.465 1.00 93.53  ? 264  LYS A O   1 
ATOM 2084 C CB  . LYS A 1 264  ? 96.967  65.003  112.771 1.00 132.25 ? 264  LYS A CB  1 
ATOM 2085 C CG  . LYS A 1 264  ? 97.859  64.211  111.822 1.00 146.70 ? 264  LYS A CG  1 
ATOM 2086 C CD  . LYS A 1 264  ? 97.710  64.563  110.353 1.00 159.34 ? 264  LYS A CD  1 
ATOM 2087 C CE  . LYS A 1 264  ? 96.308  64.377  109.808 1.00 170.29 ? 264  LYS A CE  1 
ATOM 2088 N NZ  . LYS A 1 264  ? 95.831  62.979  109.937 1.00 174.98 ? 264  LYS A NZ  1 
ATOM 2089 N N   . VAL A 1 265  ? 95.435  65.489  115.761 1.00 88.30  ? 265  VAL A N   1 
ATOM 2090 C CA  . VAL A 1 265  ? 94.843  66.448  116.680 1.00 76.62  ? 265  VAL A CA  1 
ATOM 2091 C C   . VAL A 1 265  ? 95.861  66.658  117.787 1.00 71.10  ? 265  VAL A C   1 
ATOM 2092 O O   . VAL A 1 265  ? 96.137  67.788  118.173 1.00 78.91  ? 265  VAL A O   1 
ATOM 2093 C CB  . VAL A 1 265  ? 93.489  66.017  117.286 1.00 80.97  ? 265  VAL A CB  1 
ATOM 2094 C CG1 . VAL A 1 265  ? 92.895  67.109  118.163 1.00 85.45  ? 265  VAL A CG1 1 
ATOM 2095 C CG2 . VAL A 1 265  ? 92.454  65.605  116.255 1.00 81.67  ? 265  VAL A CG2 1 
ATOM 2096 N N   . ARG A 1 266  ? 96.402  65.549  118.290 1.00 73.67  ? 266  ARG A N   1 
ATOM 2097 C CA  . ARG A 1 266  ? 97.329  65.587  119.402 1.00 88.74  ? 266  ARG A CA  1 
ATOM 2098 C C   . ARG A 1 266  ? 98.543  66.430  119.036 1.00 95.56  ? 266  ARG A C   1 
ATOM 2099 O O   . ARG A 1 266  ? 99.019  67.201  119.866 1.00 108.25 ? 266  ARG A O   1 
ATOM 2100 C CB  . ARG A 1 266  ? 97.770  64.177  119.801 1.00 101.59 ? 266  ARG A CB  1 
ATOM 2101 C CG  . ARG A 1 266  ? 98.754  64.125  120.964 1.00 109.56 ? 266  ARG A CG  1 
ATOM 2102 C CD  . ARG A 1 266  ? 99.189  62.699  121.266 1.00 112.59 ? 266  ARG A CD  1 
ATOM 2103 N NE  . ARG A 1 266  ? 98.052  61.861  121.635 1.00 118.27 ? 266  ARG A NE  1 
ATOM 2104 C CZ  . ARG A 1 266  ? 97.605  60.819  120.939 1.00 125.22 ? 266  ARG A CZ  1 
ATOM 2105 N NH1 . ARG A 1 266  ? 98.247  60.414  119.857 1.00 125.34 ? 266  ARG A NH1 1 
ATOM 2106 N NH2 . ARG A 1 266  ? 96.517  60.179  121.331 1.00 130.19 ? 266  ARG A NH2 1 
ATOM 2107 N N   . GLU A 1 267  ? 99.040  66.278  117.807 1.00 105.57 ? 267  GLU A N   1 
ATOM 2108 C CA  . GLU A 1 267  ? 100.235 67.000  117.401 1.00 133.05 ? 267  GLU A CA  1 
ATOM 2109 C C   . GLU A 1 267  ? 99.989  68.498  117.553 1.00 134.88 ? 267  GLU A C   1 
ATOM 2110 O O   . GLU A 1 267  ? 100.821 69.212  118.106 1.00 132.11 ? 267  GLU A O   1 
ATOM 2111 C CB  . GLU A 1 267  ? 100.630 66.658  115.965 1.00 162.60 ? 267  GLU A CB  1 
ATOM 2112 C CG  . GLU A 1 267  ? 100.918 65.182  115.751 1.00 193.00 ? 267  GLU A CG  1 
ATOM 2113 C CD  . GLU A 1 267  ? 101.293 64.799  114.329 1.00 218.41 ? 267  GLU A CD  1 
ATOM 2114 O OE1 . GLU A 1 267  ? 101.487 63.593  114.077 1.00 229.71 ? 267  GLU A OE1 1 
ATOM 2115 O OE2 . GLU A 1 267  ? 101.403 65.708  113.480 1.00 232.70 ? 267  GLU A OE2 1 
ATOM 2116 N N   . ARG A 1 268  ? 98.824  68.940  117.069 1.00 131.22 ? 268  ARG A N   1 
ATOM 2117 C CA  . ARG A 1 268  ? 98.409  70.333  117.108 1.00 131.73 ? 268  ARG A CA  1 
ATOM 2118 C C   . ARG A 1 268  ? 98.412  70.854  118.539 1.00 115.28 ? 268  ARG A C   1 
ATOM 2119 O O   . ARG A 1 268  ? 98.962  71.917  118.814 1.00 112.34 ? 268  ARG A O   1 
ATOM 2120 C CB  . ARG A 1 268  ? 96.988  70.440  116.548 1.00 147.83 ? 268  ARG A CB  1 
ATOM 2121 C CG  . ARG A 1 268  ? 96.407  71.845  116.467 1.00 162.15 ? 268  ARG A CG  1 
ATOM 2122 C CD  . ARG A 1 268  ? 97.152  72.801  115.555 1.00 168.56 ? 268  ARG A CD  1 
ATOM 2123 N NE  . ARG A 1 268  ? 96.376  74.023  115.432 1.00 170.21 ? 268  ARG A NE  1 
ATOM 2124 C CZ  . ARG A 1 268  ? 95.807  74.453  114.312 1.00 165.39 ? 268  ARG A CZ  1 
ATOM 2125 N NH1 . ARG A 1 268  ? 96.017  73.826  113.168 1.00 158.52 ? 268  ARG A NH1 1 
ATOM 2126 N NH2 . ARG A 1 268  ? 95.042  75.530  114.335 1.00 165.35 ? 268  ARG A NH2 1 
ATOM 2127 N N   . MET A 1 269  ? 97.731  70.122  119.426 1.00 106.24 ? 269  MET A N   1 
ATOM 2128 C CA  . MET A 1 269  ? 97.567  70.558  120.801 1.00 97.51  ? 269  MET A CA  1 
ATOM 2129 C C   . MET A 1 269  ? 98.938  70.636  121.462 1.00 89.23  ? 269  MET A C   1 
ATOM 2130 O O   . MET A 1 269  ? 99.226  71.597  122.171 1.00 96.73  ? 269  MET A O   1 
ATOM 2131 C CB  . MET A 1 269  ? 96.643  69.620  121.584 1.00 96.52  ? 269  MET A CB  1 
ATOM 2132 C CG  . MET A 1 269  ? 95.181  70.022  121.484 1.00 102.02 ? 269  MET A CG  1 
ATOM 2133 S SD  . MET A 1 269  ? 94.071  68.899  122.365 1.00 117.06 ? 269  MET A SD  1 
ATOM 2134 C CE  . MET A 1 269  ? 94.027  69.683  123.980 1.00 133.52 ? 269  MET A CE  1 
ATOM 2135 N N   . THR A 1 270  ? 99.787  69.642  121.193 1.00 89.37  ? 270  THR A N   1 
ATOM 2136 C CA  . THR A 1 270  ? 101.139 69.644  121.720 1.00 99.23  ? 270  THR A CA  1 
ATOM 2137 C C   . THR A 1 270  ? 101.888 70.857  121.181 1.00 106.49 ? 270  THR A C   1 
ATOM 2138 O O   . THR A 1 270  ? 102.622 71.508  121.922 1.00 121.10 ? 270  THR A O   1 
ATOM 2139 C CB  . THR A 1 270  ? 101.872 68.342  121.378 1.00 117.12 ? 270  THR A CB  1 
ATOM 2140 O OG1 . THR A 1 270  ? 101.106 67.253  121.895 1.00 119.20 ? 270  THR A OG1 1 
ATOM 2141 C CG2 . THR A 1 270  ? 103.275 68.288  121.944 1.00 129.95 ? 270  THR A CG2 1 
ATOM 2142 N N   . LYS A 1 271  ? 101.694 71.153  119.891 1.00 107.98 ? 271  LYS A N   1 
ATOM 2143 C CA  . LYS A 1 271  ? 102.368 72.269  119.248 1.00 123.29 ? 271  LYS A CA  1 
ATOM 2144 C C   . LYS A 1 271  ? 101.978 73.578  119.932 1.00 110.93 ? 271  LYS A C   1 
ATOM 2145 O O   . LYS A 1 271  ? 102.836 74.422  120.184 1.00 106.69 ? 271  LYS A O   1 
ATOM 2146 C CB  . LYS A 1 271  ? 102.032 72.304  117.753 1.00 145.71 ? 271  LYS A CB  1 
ATOM 2147 C CG  . LYS A 1 271  ? 102.705 73.413  116.954 1.00 164.02 ? 271  LYS A CG  1 
ATOM 2148 C CD  . LYS A 1 271  ? 104.221 73.356  116.972 1.00 172.55 ? 271  LYS A CD  1 
ATOM 2149 C CE  . LYS A 1 271  ? 104.863 74.453  116.150 1.00 179.49 ? 271  LYS A CE  1 
ATOM 2150 N NZ  . LYS A 1 271  ? 104.630 75.795  116.739 1.00 184.63 ? 271  LYS A NZ  1 
ATOM 2151 N N   . PHE A 1 272  ? 100.682 73.718  120.245 1.00 99.71  ? 272  PHE A N   1 
ATOM 2152 C CA  . PHE A 1 272  ? 100.136 74.947  120.801 1.00 89.81  ? 272  PHE A CA  1 
ATOM 2153 C C   . PHE A 1 272  ? 100.749 75.232  122.169 1.00 84.88  ? 272  PHE A C   1 
ATOM 2154 O O   . PHE A 1 272  ? 101.324 76.292  122.383 1.00 88.99  ? 272  PHE A O   1 
ATOM 2155 C CB  . PHE A 1 272  ? 98.612  74.865  120.889 1.00 88.32  ? 272  PHE A CB  1 
ATOM 2156 C CG  . PHE A 1 272  ? 97.938  76.082  121.468 1.00 94.31  ? 272  PHE A CG  1 
ATOM 2157 C CD1 . PHE A 1 272  ? 98.019  77.314  120.839 1.00 103.16 ? 272  PHE A CD1 1 
ATOM 2158 C CD2 . PHE A 1 272  ? 97.205  75.989  122.641 1.00 114.95 ? 272  PHE A CD2 1 
ATOM 2159 C CE1 . PHE A 1 272  ? 97.374  78.424  121.369 1.00 118.24 ? 272  PHE A CE1 1 
ATOM 2160 C CE2 . PHE A 1 272  ? 96.575  77.102  123.179 1.00 125.19 ? 272  PHE A CE2 1 
ATOM 2161 C CZ  . PHE A 1 272  ? 96.663  78.322  122.546 1.00 126.43 ? 272  PHE A CZ  1 
ATOM 2162 N N   . ILE A 1 273  ? 100.654 74.261  123.081 1.00 84.14  ? 273  ILE A N   1 
ATOM 2163 C CA  . ILE A 1 273  ? 100.985 74.497  124.476 1.00 84.23  ? 273  ILE A CA  1 
ATOM 2164 C C   . ILE A 1 273  ? 102.482 74.767  124.606 1.00 92.10  ? 273  ILE A C   1 
ATOM 2165 O O   . ILE A 1 273  ? 102.882 75.562  125.455 1.00 99.79  ? 273  ILE A O   1 
ATOM 2166 C CB  . ILE A 1 273  ? 100.534 73.324  125.366 1.00 91.33  ? 273  ILE A CB  1 
ATOM 2167 C CG1 . ILE A 1 273  ? 99.079  72.930  125.098 1.00 95.28  ? 273  ILE A CG1 1 
ATOM 2168 C CG2 . ILE A 1 273  ? 100.749 73.649  126.839 1.00 103.02 ? 273  ILE A CG2 1 
ATOM 2169 C CD1 . ILE A 1 273  ? 98.670  71.623  125.744 1.00 104.57 ? 273  ILE A CD1 1 
ATOM 2170 N N   . ASP A 1 274  ? 103.299 74.120  123.764 1.00 106.45 ? 274  ASP A N   1 
ATOM 2171 C CA  . ASP A 1 274  ? 104.746 74.191  123.897 1.00 130.90 ? 274  ASP A CA  1 
ATOM 2172 C C   . ASP A 1 274  ? 105.100 73.809  125.332 1.00 136.54 ? 274  ASP A C   1 
ATOM 2173 O O   . ASP A 1 274  ? 105.892 74.475  125.996 1.00 126.07 ? 274  ASP A O   1 
ATOM 2174 C CB  . ASP A 1 274  ? 105.258 75.580  123.505 1.00 158.13 ? 274  ASP A CB  1 
ATOM 2175 C CG  . ASP A 1 274  ? 106.742 75.641  123.180 1.00 183.89 ? 274  ASP A CG  1 
ATOM 2176 O OD1 . ASP A 1 274  ? 107.555 75.249  124.044 1.00 184.60 ? 274  ASP A OD1 1 
ATOM 2177 O OD2 . ASP A 1 274  ? 107.075 76.104  122.068 1.00 202.64 ? 274  ASP A OD2 1 
ATOM 2178 N N   . ASP A 1 275  ? 104.488 72.711  125.788 1.00 166.20 ? 275  ASP A N   1 
ATOM 2179 C CA  . ASP A 1 275  ? 104.413 72.365  127.200 1.00 191.68 ? 275  ASP A CA  1 
ATOM 2180 C C   . ASP A 1 275  ? 105.758 71.886  127.744 1.00 181.58 ? 275  ASP A C   1 
ATOM 2181 O O   . ASP A 1 275  ? 106.099 72.192  128.886 1.00 176.63 ? 275  ASP A O   1 
ATOM 2182 C CB  . ASP A 1 275  ? 103.345 71.296  127.457 1.00 218.53 ? 275  ASP A CB  1 
ATOM 2183 C CG  . ASP A 1 275  ? 103.327 70.128  126.482 1.00 240.87 ? 275  ASP A CG  1 
ATOM 2184 O OD1 . ASP A 1 275  ? 104.175 70.108  125.566 1.00 252.24 ? 275  ASP A OD1 1 
ATOM 2185 O OD2 . ASP A 1 275  ? 102.447 69.254  126.635 1.00 249.04 ? 275  ASP A OD2 1 
ATOM 2186 N N   . THR A 1 276  ? 106.502 71.111  126.947 1.00 172.30 ? 276  THR A N   1 
ATOM 2187 C CA  . THR A 1 276  ? 107.548 70.271  127.504 1.00 163.37 ? 276  THR A CA  1 
ATOM 2188 C C   . THR A 1 276  ? 106.859 69.440  128.585 1.00 155.37 ? 276  THR A C   1 
ATOM 2189 O O   . THR A 1 276  ? 105.844 68.819  128.295 1.00 148.31 ? 276  THR A O   1 
ATOM 2190 C CB  . THR A 1 276  ? 108.757 71.118  127.930 1.00 166.04 ? 276  THR A CB  1 
ATOM 2191 O OG1 . THR A 1 276  ? 108.498 71.766  129.176 1.00 169.40 ? 276  THR A OG1 1 
ATOM 2192 C CG2 . THR A 1 276  ? 109.116 72.167  126.900 1.00 169.64 ? 276  THR A CG2 1 
ATOM 2193 N N   . MET A 1 277  ? 107.339 69.498  129.833 1.00 158.40 ? 277  MET A N   1 
ATOM 2194 C CA  . MET A 1 277  ? 106.631 68.888  130.951 1.00 160.53 ? 277  MET A CA  1 
ATOM 2195 C C   . MET A 1 277  ? 105.171 69.332  130.911 1.00 143.89 ? 277  MET A C   1 
ATOM 2196 O O   . MET A 1 277  ? 104.888 70.469  130.548 1.00 141.29 ? 277  MET A O   1 
ATOM 2197 C CB  . MET A 1 277  ? 107.247 69.284  132.300 1.00 186.51 ? 277  MET A CB  1 
ATOM 2198 C CG  . MET A 1 277  ? 108.169 68.230  132.895 1.00 209.35 ? 277  MET A CG  1 
ATOM 2199 S SD  . MET A 1 277  ? 107.289 66.903  133.772 1.00 239.70 ? 277  MET A SD  1 
ATOM 2200 C CE  . MET A 1 277  ? 107.146 65.667  132.481 1.00 246.74 ? 277  MET A CE  1 
ATOM 2201 N N   . ARG A 1 278  ? 104.262 68.431  131.306 1.00 145.53 ? 278  ARG A N   1 
ATOM 2202 C CA  . ARG A 1 278  ? 102.866 68.497  130.897 1.00 153.36 ? 278  ARG A CA  1 
ATOM 2203 C C   . ARG A 1 278  ? 102.742 67.712  129.590 1.00 177.69 ? 278  ARG A C   1 
ATOM 2204 O O   . ARG A 1 278  ? 101.649 67.547  129.052 1.00 184.63 ? 278  ARG A O   1 
ATOM 2205 C CB  . ARG A 1 278  ? 102.413 69.958  130.771 1.00 148.92 ? 278  ARG A CB  1 
ATOM 2206 C CG  . ARG A 1 278  ? 100.919 70.192  130.600 1.00 142.30 ? 278  ARG A CG  1 
ATOM 2207 C CD  . ARG A 1 278  ? 100.695 71.598  130.061 1.00 127.60 ? 278  ARG A CD  1 
ATOM 2208 N NE  . ARG A 1 278  ? 99.328  72.075  130.209 1.00 118.37 ? 278  ARG A NE  1 
ATOM 2209 C CZ  . ARG A 1 278  ? 98.263  71.557  129.603 1.00 116.89 ? 278  ARG A CZ  1 
ATOM 2210 N NH1 . ARG A 1 278  ? 97.063  72.046  129.862 1.00 121.88 ? 278  ARG A NH1 1 
ATOM 2211 N NH2 . ARG A 1 278  ? 98.387  70.554  128.750 1.00 118.08 ? 278  ARG A NH2 1 
ATOM 2212 N N   . GLU A 1 279  ? 103.893 67.241  129.086 1.00 192.92 ? 279  GLU A N   1 
ATOM 2213 C CA  . GLU A 1 279  ? 103.957 66.233  128.039 1.00 207.10 ? 279  GLU A CA  1 
ATOM 2214 C C   . GLU A 1 279  ? 103.580 64.869  128.614 1.00 205.89 ? 279  GLU A C   1 
ATOM 2215 O O   . GLU A 1 279  ? 103.456 64.722  129.826 1.00 206.99 ? 279  GLU A O   1 
ATOM 2216 C CB  . GLU A 1 279  ? 105.367 66.168  127.444 1.00 223.01 ? 279  GLU A CB  1 
ATOM 2217 C CG  . GLU A 1 279  ? 106.449 65.826  128.464 1.00 246.50 ? 279  GLU A CG  1 
ATOM 2218 C CD  . GLU A 1 279  ? 107.882 66.046  128.007 1.00 270.94 ? 279  GLU A CD  1 
ATOM 2219 O OE1 . GLU A 1 279  ? 108.801 65.709  128.782 1.00 283.01 ? 279  GLU A OE1 1 
ATOM 2220 O OE2 . GLU A 1 279  ? 108.078 66.562  126.888 1.00 282.60 ? 279  GLU A OE2 1 
ATOM 2221 N N   . THR A 1 280  ? 103.434 63.882  127.718 1.00 200.19 ? 280  THR A N   1 
ATOM 2222 C CA  . THR A 1 280  ? 103.181 62.485  128.051 1.00 194.95 ? 280  THR A CA  1 
ATOM 2223 C C   . THR A 1 280  ? 101.692 62.273  128.300 1.00 183.46 ? 280  THR A C   1 
ATOM 2224 O O   . THR A 1 280  ? 101.032 61.579  127.534 1.00 188.89 ? 280  THR A O   1 
ATOM 2225 C CB  . THR A 1 280  ? 103.987 61.969  129.253 1.00 201.36 ? 280  THR A CB  1 
ATOM 2226 O OG1 . THR A 1 280  ? 103.453 62.525  130.455 1.00 196.92 ? 280  THR A OG1 1 
ATOM 2227 C CG2 . THR A 1 280  ? 105.469 62.260  129.156 1.00 207.51 ? 280  THR A CG2 1 
ATOM 2228 N N   . ALA A 1 281  ? 101.182 62.848  129.393 1.00 173.80 ? 281  ALA A N   1 
ATOM 2229 C CA  . ALA A 1 281  ? 99.753  62.826  129.651 1.00 173.34 ? 281  ALA A CA  1 
ATOM 2230 C C   . ALA A 1 281  ? 99.045  63.336  128.402 1.00 167.61 ? 281  ALA A C   1 
ATOM 2231 O O   . ALA A 1 281  ? 99.498  64.312  127.803 1.00 167.86 ? 281  ALA A O   1 
ATOM 2232 C CB  . ALA A 1 281  ? 99.428  63.665  130.862 1.00 181.06 ? 281  ALA A CB  1 
ATOM 2233 N N   . GLU A 1 282  ? 97.978  62.641  127.985 1.00 161.63 ? 282  GLU A N   1 
ATOM 2234 C CA  . GLU A 1 282  ? 97.232  63.052  126.807 1.00 155.21 ? 282  GLU A CA  1 
ATOM 2235 C C   . GLU A 1 282  ? 97.024  64.557  126.906 1.00 141.49 ? 282  GLU A C   1 
ATOM 2236 O O   . GLU A 1 282  ? 96.420  65.010  127.872 1.00 150.84 ? 282  GLU A O   1 
ATOM 2237 C CB  . GLU A 1 282  ? 95.883  62.336  126.699 1.00 163.36 ? 282  GLU A CB  1 
ATOM 2238 C CG  . GLU A 1 282  ? 95.985  60.839  126.450 1.00 184.33 ? 282  GLU A CG  1 
ATOM 2239 C CD  . GLU A 1 282  ? 96.556  60.421  125.102 1.00 197.13 ? 282  GLU A CD  1 
ATOM 2240 O OE1 . GLU A 1 282  ? 95.924  60.717  124.064 1.00 200.56 ? 282  GLU A OE1 1 
ATOM 2241 O OE2 . GLU A 1 282  ? 97.629  59.782  125.096 1.00 202.08 ? 282  GLU A OE2 1 
ATOM 2242 N N   . PRO A 1 283  ? 97.561  65.375  125.972 1.00 127.57 ? 283  PRO A N   1 
ATOM 2243 C CA  . PRO A 1 283  ? 97.537  66.827  126.131 1.00 124.51 ? 283  PRO A CA  1 
ATOM 2244 C C   . PRO A 1 283  ? 96.097  67.307  126.282 1.00 129.79 ? 283  PRO A C   1 
ATOM 2245 O O   . PRO A 1 283  ? 95.201  66.798  125.615 1.00 118.55 ? 283  PRO A O   1 
ATOM 2246 C CB  . PRO A 1 283  ? 98.208  67.356  124.856 1.00 128.89 ? 283  PRO A CB  1 
ATOM 2247 C CG  . PRO A 1 283  ? 99.027  66.185  124.361 1.00 132.67 ? 283  PRO A CG  1 
ATOM 2248 C CD  . PRO A 1 283  ? 98.207  64.964  124.717 1.00 131.21 ? 283  PRO A CD  1 
ATOM 2249 N N   . PHE A 1 284  ? 95.902  68.256  127.203 1.00 135.03 ? 284  PHE A N   1 
ATOM 2250 C CA  . PHE A 1 284  ? 94.590  68.770  127.563 1.00 131.97 ? 284  PHE A CA  1 
ATOM 2251 C C   . PHE A 1 284  ? 94.680  70.291  127.607 1.00 124.88 ? 284  PHE A C   1 
ATOM 2252 O O   . PHE A 1 284  ? 95.710  70.829  128.002 1.00 123.06 ? 284  PHE A O   1 
ATOM 2253 C CB  . PHE A 1 284  ? 94.133  68.201  128.912 1.00 137.20 ? 284  PHE A CB  1 
ATOM 2254 C CG  . PHE A 1 284  ? 94.814  68.789  130.125 1.00 142.64 ? 284  PHE A CG  1 
ATOM 2255 C CD1 . PHE A 1 284  ? 96.196  68.763  130.259 1.00 144.07 ? 284  PHE A CD1 1 
ATOM 2256 C CD2 . PHE A 1 284  ? 94.071  69.374  131.139 1.00 144.26 ? 284  PHE A CD2 1 
ATOM 2257 C CE1 . PHE A 1 284  ? 96.818  69.309  131.371 1.00 139.87 ? 284  PHE A CE1 1 
ATOM 2258 C CE2 . PHE A 1 284  ? 94.695  69.922  132.250 1.00 148.76 ? 284  PHE A CE2 1 
ATOM 2259 C CZ  . PHE A 1 284  ? 96.066  69.887  132.366 1.00 144.15 ? 284  PHE A CZ  1 
ATOM 2260 N N   . LEU A 1 285  ? 93.606  70.978  127.205 1.00 113.61 ? 285  LEU A N   1 
ATOM 2261 C CA  . LEU A 1 285  ? 93.614  72.430  127.188 1.00 106.53 ? 285  LEU A CA  1 
ATOM 2262 C C   . LEU A 1 285  ? 92.607  72.975  128.196 1.00 107.75 ? 285  LEU A C   1 
ATOM 2263 O O   . LEU A 1 285  ? 91.455  72.551  128.200 1.00 99.51  ? 285  LEU A O   1 
ATOM 2264 C CB  . LEU A 1 285  ? 93.321  72.912  125.764 1.00 107.35 ? 285  LEU A CB  1 
ATOM 2265 C CG  . LEU A 1 285  ? 94.543  73.097  124.861 1.00 114.92 ? 285  LEU A CG  1 
ATOM 2266 C CD1 . LEU A 1 285  ? 94.194  73.939  123.641 1.00 117.31 ? 285  LEU A CD1 1 
ATOM 2267 C CD2 . LEU A 1 285  ? 95.706  73.730  125.614 1.00 109.49 ? 285  LEU A CD2 1 
ATOM 2268 N N   . PHE A 1 286  ? 93.072  73.922  129.037 1.00 105.73 ? 286  PHE A N   1 
ATOM 2269 C CA  . PHE A 1 286  ? 92.245  74.583  130.041 1.00 99.94  ? 286  PHE A CA  1 
ATOM 2270 C C   . PHE A 1 286  ? 91.308  75.593  129.384 1.00 82.26  ? 286  PHE A C   1 
ATOM 2271 O O   . PHE A 1 286  ? 91.689  76.243  128.414 1.00 82.47  ? 286  PHE A O   1 
ATOM 2272 C CB  . PHE A 1 286  ? 93.087  75.387  131.035 1.00 105.85 ? 286  PHE A CB  1 
ATOM 2273 C CG  . PHE A 1 286  ? 93.991  74.591  131.939 1.00 115.66 ? 286  PHE A CG  1 
ATOM 2274 C CD1 . PHE A 1 286  ? 93.485  73.600  132.767 1.00 116.60 ? 286  PHE A CD1 1 
ATOM 2275 C CD2 . PHE A 1 286  ? 95.347  74.874  131.992 1.00 122.27 ? 286  PHE A CD2 1 
ATOM 2276 C CE1 . PHE A 1 286  ? 94.328  72.885  133.604 1.00 123.86 ? 286  PHE A CE1 1 
ATOM 2277 C CE2 . PHE A 1 286  ? 96.188  74.163  132.835 1.00 123.28 ? 286  PHE A CE2 1 
ATOM 2278 C CZ  . PHE A 1 286  ? 95.677  73.165  133.633 1.00 126.62 ? 286  PHE A CZ  1 
ATOM 2279 N N   . VAL A 1 287  ? 90.126  75.800  129.973 1.00 68.08  ? 287  VAL A N   1 
ATOM 2280 C CA  . VAL A 1 287  ? 89.148  76.700  129.387 1.00 65.93  ? 287  VAL A CA  1 
ATOM 2281 C C   . VAL A 1 287  ? 89.814  78.034  129.063 1.00 64.39  ? 287  VAL A C   1 
ATOM 2282 O O   . VAL A 1 287  ? 89.444  78.674  128.083 1.00 64.29  ? 287  VAL A O   1 
ATOM 2283 C CB  . VAL A 1 287  ? 87.908  76.881  130.280 1.00 72.42  ? 287  VAL A CB  1 
ATOM 2284 C CG1 . VAL A 1 287  ? 86.964  77.955  129.760 1.00 73.37  ? 287  VAL A CG1 1 
ATOM 2285 C CG2 . VAL A 1 287  ? 87.158  75.568  130.431 1.00 80.94  ? 287  VAL A CG2 1 
ATOM 2286 N N   . ASP A 1 288  ? 90.806  78.449  129.857 1.00 70.79  ? 288  ASP A N   1 
ATOM 2287 C CA  . ASP A 1 288  ? 91.534  79.659  129.519 1.00 83.68  ? 288  ASP A CA  1 
ATOM 2288 C C   . ASP A 1 288  ? 92.260  79.498  128.197 1.00 76.19  ? 288  ASP A C   1 
ATOM 2289 O O   . ASP A 1 288  ? 92.243  80.404  127.370 1.00 88.04  ? 288  ASP A O   1 
ATOM 2290 C CB  . ASP A 1 288  ? 92.628  80.052  130.509 1.00 106.51 ? 288  ASP A CB  1 
ATOM 2291 C CG  . ASP A 1 288  ? 93.366  81.290  130.025 1.00 121.35 ? 288  ASP A CG  1 
ATOM 2292 O OD1 . ASP A 1 288  ? 92.723  82.350  129.915 1.00 130.51 ? 288  ASP A OD1 1 
ATOM 2293 O OD2 . ASP A 1 288  ? 94.545  81.168  129.675 1.00 124.77 ? 288  ASP A OD2 1 
ATOM 2294 N N   . GLU A 1 289  ? 92.942  78.367  128.034 1.00 66.55  ? 289  GLU A N   1 
ATOM 2295 C CA  . GLU A 1 289  ? 93.794  78.211  126.878 1.00 66.81  ? 289  GLU A CA  1 
ATOM 2296 C C   . GLU A 1 289  ? 92.912  78.125  125.639 1.00 60.09  ? 289  GLU A C   1 
ATOM 2297 O O   . GLU A 1 289  ? 93.202  78.798  124.658 1.00 62.99  ? 289  GLU A O   1 
ATOM 2298 C CB  . GLU A 1 289  ? 94.734  77.022  127.049 1.00 84.88  ? 289  GLU A CB  1 
ATOM 2299 C CG  . GLU A 1 289  ? 96.191  77.394  126.828 1.00 101.65 ? 289  GLU A CG  1 
ATOM 2300 C CD  . GLU A 1 289  ? 96.712  78.455  127.782 1.00 118.25 ? 289  GLU A CD  1 
ATOM 2301 O OE1 . GLU A 1 289  ? 97.870  78.895  127.607 1.00 134.52 ? 289  GLU A OE1 1 
ATOM 2302 O OE2 . GLU A 1 289  ? 95.962  78.828  128.707 1.00 118.38 ? 289  GLU A OE2 1 
ATOM 2303 N N   . PHE A 1 290  ? 91.797  77.385  125.706 1.00 51.84  ? 290  PHE A N   1 
ATOM 2304 C CA  . PHE A 1 290  ? 90.895  77.315  124.566 1.00 47.87  ? 290  PHE A CA  1 
ATOM 2305 C C   . PHE A 1 290  ? 90.698  78.725  124.011 1.00 55.90  ? 290  PHE A C   1 
ATOM 2306 O O   . PHE A 1 290  ? 90.757  78.919  122.801 1.00 66.98  ? 290  PHE A O   1 
ATOM 2307 C CB  . PHE A 1 290  ? 89.559  76.667  124.920 1.00 44.66  ? 290  PHE A CB  1 
ATOM 2308 C CG  . PHE A 1 290  ? 88.788  76.167  123.732 1.00 50.89  ? 290  PHE A CG  1 
ATOM 2309 C CD1 . PHE A 1 290  ? 89.310  75.162  122.929 1.00 65.41  ? 290  PHE A CD1 1 
ATOM 2310 C CD2 . PHE A 1 290  ? 87.533  76.677  123.427 1.00 57.83  ? 290  PHE A CD2 1 
ATOM 2311 C CE1 . PHE A 1 290  ? 88.600  74.687  121.831 1.00 78.55  ? 290  PHE A CE1 1 
ATOM 2312 C CE2 . PHE A 1 290  ? 86.833  76.213  122.321 1.00 69.76  ? 290  PHE A CE2 1 
ATOM 2313 C CZ  . PHE A 1 290  ? 87.364  75.215  121.530 1.00 77.78  ? 290  PHE A CZ  1 
ATOM 2314 N N   . LEU A 1 291  ? 90.546  79.727  124.889 1.00 56.64  ? 291  LEU A N   1 
ATOM 2315 C CA  . LEU A 1 291  ? 90.333  81.098  124.449 1.00 56.89  ? 291  LEU A CA  1 
ATOM 2316 C C   . LEU A 1 291  ? 91.608  81.697  123.856 1.00 49.92  ? 291  LEU A C   1 
ATOM 2317 O O   . LEU A 1 291  ? 91.525  82.539  122.961 1.00 61.30  ? 291  LEU A O   1 
ATOM 2318 C CB  . LEU A 1 291  ? 89.816  81.948  125.611 1.00 64.99  ? 291  LEU A CB  1 
ATOM 2319 C CG  . LEU A 1 291  ? 89.447  83.390  125.257 1.00 78.79  ? 291  LEU A CG  1 
ATOM 2320 C CD1 . LEU A 1 291  ? 88.141  83.455  124.467 1.00 81.25  ? 291  LEU A CD1 1 
ATOM 2321 C CD2 . LEU A 1 291  ? 89.361  84.238  126.519 1.00 87.87  ? 291  LEU A CD2 1 
ATOM 2322 N N   . THR A 1 292  ? 92.783  81.284  124.330 1.00 43.69  ? 292  THR A N   1 
ATOM 2323 C CA  . THR A 1 292  ? 94.017  81.774  123.741 1.00 45.58  ? 292  THR A CA  1 
ATOM 2324 C C   . THR A 1 292  ? 94.250  81.107  122.390 1.00 42.82  ? 292  THR A C   1 
ATOM 2325 O O   . THR A 1 292  ? 94.780  81.756  121.494 1.00 48.30  ? 292  THR A O   1 
ATOM 2326 C CB  . THR A 1 292  ? 95.223  81.617  124.676 1.00 56.65  ? 292  THR A CB  1 
ATOM 2327 O OG1 . THR A 1 292  ? 94.957  82.370  125.863 1.00 62.17  ? 292  THR A OG1 1 
ATOM 2328 C CG2 . THR A 1 292  ? 96.517  82.105  124.060 1.00 61.48  ? 292  THR A CG2 1 
ATOM 2329 N N   . TYR A 1 293  ? 93.856  79.839  122.223 1.00 43.15  ? 293  TYR A N   1 
ATOM 2330 C CA  . TYR A 1 293  ? 93.924  79.204  120.912 1.00 48.89  ? 293  TYR A CA  1 
ATOM 2331 C C   . TYR A 1 293  ? 92.997  79.979  119.981 1.00 44.76  ? 293  TYR A C   1 
ATOM 2332 O O   . TYR A 1 293  ? 93.439  80.464  118.938 1.00 47.68  ? 293  TYR A O   1 
ATOM 2333 C CB  . TYR A 1 293  ? 93.623  77.699  121.015 1.00 55.50  ? 293  TYR A CB  1 
ATOM 2334 C CG  . TYR A 1 293  ? 93.577  76.892  119.739 1.00 59.59  ? 293  TYR A CG  1 
ATOM 2335 C CD1 . TYR A 1 293  ? 92.572  77.077  118.809 1.00 66.50  ? 293  TYR A CD1 1 
ATOM 2336 C CD2 . TYR A 1 293  ? 94.501  75.896  119.490 1.00 69.79  ? 293  TYR A CD2 1 
ATOM 2337 C CE1 . TYR A 1 293  ? 92.502  76.326  117.645 1.00 73.45  ? 293  TYR A CE1 1 
ATOM 2338 C CE2 . TYR A 1 293  ? 94.452  75.135  118.336 1.00 80.86  ? 293  TYR A CE2 1 
ATOM 2339 C CZ  . TYR A 1 293  ? 93.460  75.359  117.395 1.00 81.65  ? 293  TYR A CZ  1 
ATOM 2340 O OH  . TYR A 1 293  ? 93.432  74.606  116.241 1.00 88.34  ? 293  TYR A OH  1 
ATOM 2341 N N   . LEU A 1 294  ? 91.727  80.121  120.368 1.00 35.50  ? 294  LEU A N   1 
ATOM 2342 C CA  . LEU A 1 294  ? 90.775  80.686  119.438 1.00 35.72  ? 294  LEU A CA  1 
ATOM 2343 C C   . LEU A 1 294  ? 91.343  81.984  118.863 1.00 41.58  ? 294  LEU A C   1 
ATOM 2344 O O   . LEU A 1 294  ? 91.508  82.090  117.655 1.00 46.21  ? 294  LEU A O   1 
ATOM 2345 C CB  . LEU A 1 294  ? 89.422  80.881  120.117 1.00 34.46  ? 294  LEU A CB  1 
ATOM 2346 C CG  . LEU A 1 294  ? 88.640  79.606  120.418 1.00 36.77  ? 294  LEU A CG  1 
ATOM 2347 C CD1 . LEU A 1 294  ? 87.144  79.865  120.384 1.00 39.27  ? 294  LEU A CD1 1 
ATOM 2348 C CD2 . LEU A 1 294  ? 88.978  78.479  119.459 1.00 40.49  ? 294  LEU A CD2 1 
ATOM 2349 N N   . PHE A 1 295  ? 91.672  82.967  119.702 1.00 43.99  ? 295  PHE A N   1 
ATOM 2350 C CA  . PHE A 1 295  ? 92.242  84.209  119.206 1.00 47.40  ? 295  PHE A CA  1 
ATOM 2351 C C   . PHE A 1 295  ? 93.719  84.058  118.875 1.00 43.82  ? 295  PHE A C   1 
ATOM 2352 O O   . PHE A 1 295  ? 94.546  84.729  119.495 1.00 46.54  ? 295  PHE A O   1 
ATOM 2353 C CB  . PHE A 1 295  ? 92.213  85.314  120.263 1.00 56.23  ? 295  PHE A CB  1 
ATOM 2354 C CG  . PHE A 1 295  ? 90.864  85.825  120.681 1.00 64.74  ? 295  PHE A CG  1 
ATOM 2355 C CD1 . PHE A 1 295  ? 90.070  86.502  119.777 1.00 82.55  ? 295  PHE A CD1 1 
ATOM 2356 C CD2 . PHE A 1 295  ? 90.425  85.680  121.987 1.00 70.10  ? 295  PHE A CD2 1 
ATOM 2357 C CE1 . PHE A 1 295  ? 88.833  86.988  120.163 1.00 94.79  ? 295  PHE A CE1 1 
ATOM 2358 C CE2 . PHE A 1 295  ? 89.183  86.153  122.364 1.00 89.41  ? 295  PHE A CE2 1 
ATOM 2359 C CZ  . PHE A 1 295  ? 88.402  86.828  121.456 1.00 96.50  ? 295  PHE A CZ  1 
ATOM 2360 N N   . SER A 1 296  ? 94.057  83.244  117.879 1.00 47.03  ? 296  SER A N   1 
ATOM 2361 C CA  . SER A 1 296  ? 95.462  83.022  117.589 1.00 60.49  ? 296  SER A CA  1 
ATOM 2362 C C   . SER A 1 296  ? 95.682  82.630  116.130 1.00 78.41  ? 296  SER A C   1 
ATOM 2363 O O   . SER A 1 296  ? 94.751  82.207  115.447 1.00 86.06  ? 296  SER A O   1 
ATOM 2364 C CB  . SER A 1 296  ? 96.008  81.982  118.509 1.00 63.58  ? 296  SER A CB  1 
ATOM 2365 O OG  . SER A 1 296  ? 97.366  81.719  118.211 1.00 69.10  ? 296  SER A OG  1 
ATOM 2366 N N   . ARG A 1 297  ? 96.947  82.727  115.686 1.00 76.61  ? 297  ARG A N   1 
ATOM 2367 C CA  . ARG A 1 297  ? 97.307  82.444  114.306 1.00 74.20  ? 297  ARG A CA  1 
ATOM 2368 C C   . ARG A 1 297  ? 96.841  81.052  113.899 1.00 62.36  ? 297  ARG A C   1 
ATOM 2369 O O   . ARG A 1 297  ? 96.288  80.887  112.820 1.00 65.97  ? 297  ARG A O   1 
ATOM 2370 C CB  . ARG A 1 297  ? 98.816  82.540  114.083 1.00 78.38  ? 297  ARG A CB  1 
ATOM 2371 C CG  . ARG A 1 297  ? 99.356  83.960  114.136 1.00 92.98  ? 297  ARG A CG  1 
ATOM 2372 C CD  . ARG A 1 297  ? 100.583 84.121  113.257 1.00 102.75 ? 297  ARG A CD  1 
ATOM 2373 N NE  . ARG A 1 297  ? 101.230 82.835  113.033 1.00 106.76 ? 297  ARG A NE  1 
ATOM 2374 C CZ  . ARG A 1 297  ? 102.264 82.362  113.719 1.00 112.86 ? 297  ARG A CZ  1 
ATOM 2375 N NH1 . ARG A 1 297  ? 102.949 83.138  114.543 1.00 107.76 ? 297  ARG A NH1 1 
ATOM 2376 N NH2 . ARG A 1 297  ? 102.635 81.107  113.536 1.00 120.38 ? 297  ARG A NH2 1 
ATOM 2377 N N   . GLU A 1 298  ? 97.058  80.073  114.775 1.00 56.77  ? 298  GLU A N   1 
ATOM 2378 C CA  . GLU A 1 298  ? 96.821  78.681  114.447 1.00 61.36  ? 298  GLU A CA  1 
ATOM 2379 C C   . GLU A 1 298  ? 95.422  78.496  113.882 1.00 55.82  ? 298  GLU A C   1 
ATOM 2380 O O   . GLU A 1 298  ? 95.210  77.568  113.107 1.00 63.05  ? 298  GLU A O   1 
ATOM 2381 C CB  . GLU A 1 298  ? 97.025  77.786  115.670 1.00 82.75  ? 298  GLU A CB  1 
ATOM 2382 C CG  . GLU A 1 298  ? 98.489  77.639  116.085 1.00 108.38 ? 298  GLU A CG  1 
ATOM 2383 C CD  . GLU A 1 298  ? 99.174  78.875  116.652 1.00 125.91 ? 298  GLU A CD  1 
ATOM 2384 O OE1 . GLU A 1 298  ? 100.353 78.767  117.066 1.00 115.51 ? 298  GLU A OE1 1 
ATOM 2385 O OE2 . GLU A 1 298  ? 98.535  79.943  116.692 1.00 145.39 ? 298  GLU A OE2 1 
ATOM 2386 N N   . ASN A 1 299  ? 94.471  79.356  114.248 1.00 54.34  ? 299  ASN A N   1 
ATOM 2387 C CA  . ASN A 1 299  ? 93.102  79.143  113.806 1.00 61.68  ? 299  ASN A CA  1 
ATOM 2388 C C   . ASN A 1 299  ? 92.647  80.273  112.870 1.00 71.45  ? 299  ASN A C   1 
ATOM 2389 O O   . ASN A 1 299  ? 91.519  80.739  112.982 1.00 77.09  ? 299  ASN A O   1 
ATOM 2390 C CB  . ASN A 1 299  ? 92.207  78.923  115.027 1.00 60.26  ? 299  ASN A CB  1 
ATOM 2391 C CG  . ASN A 1 299  ? 90.782  78.605  114.643 1.00 64.32  ? 299  ASN A CG  1 
ATOM 2392 O OD1 . ASN A 1 299  ? 90.528  77.642  113.919 1.00 69.25  ? 299  ASN A OD1 1 
ATOM 2393 N ND2 . ASN A 1 299  ? 89.855  79.421  115.117 1.00 68.07  ? 299  ASN A ND2 1 
ATOM 2394 N N   . SER A 1 300  ? 93.500  80.672  111.912 1.00 65.07  ? 300  SER A N   1 
ATOM 2395 C CA  . SER A 1 300  ? 93.215  81.785  111.010 1.00 54.93  ? 300  SER A CA  1 
ATOM 2396 C C   . SER A 1 300  ? 92.080  81.440  110.046 1.00 50.32  ? 300  SER A C   1 
ATOM 2397 O O   . SER A 1 300  ? 91.990  80.307  109.592 1.00 58.11  ? 300  SER A O   1 
ATOM 2398 C CB  . SER A 1 300  ? 94.448  82.184  110.243 1.00 54.59  ? 300  SER A CB  1 
ATOM 2399 O OG  . SER A 1 300  ? 94.163  83.236  109.326 1.00 53.15  ? 300  SER A OG  1 
ATOM 2400 N N   . ILE A 1 301  ? 91.254  82.435  109.703 1.00 44.25  ? 301  ILE A N   1 
ATOM 2401 C CA  . ILE A 1 301  ? 90.195  82.281  108.714 1.00 44.98  ? 301  ILE A CA  1 
ATOM 2402 C C   . ILE A 1 301  ? 90.809  81.889  107.370 1.00 49.83  ? 301  ILE A C   1 
ATOM 2403 O O   . ILE A 1 301  ? 90.141  81.273  106.540 1.00 41.95  ? 301  ILE A O   1 
ATOM 2404 C CB  . ILE A 1 301  ? 89.386  83.587  108.604 1.00 51.65  ? 301  ILE A CB  1 
ATOM 2405 C CG1 . ILE A 1 301  ? 88.131  83.440  107.743 1.00 51.71  ? 301  ILE A CG1 1 
ATOM 2406 C CG2 . ILE A 1 301  ? 90.268  84.713  108.093 1.00 59.68  ? 301  ILE A CG2 1 
ATOM 2407 C CD1 . ILE A 1 301  ? 87.126  82.529  108.355 1.00 56.19  ? 301  ILE A CD1 1 
ATOM 2408 N N   . TRP A 1 302  ? 92.096  82.246  107.188 1.00 56.51  ? 302  TRP A N   1 
ATOM 2409 C CA  . TRP A 1 302  ? 92.886  81.907  106.012 1.00 58.19  ? 302  TRP A CA  1 
ATOM 2410 C C   . TRP A 1 302  ? 93.015  80.398  105.884 1.00 65.68  ? 302  TRP A C   1 
ATOM 2411 O O   . TRP A 1 302  ? 93.518  79.754  106.800 1.00 71.32  ? 302  TRP A O   1 
ATOM 2412 C CB  . TRP A 1 302  ? 94.271  82.546  106.135 1.00 60.21  ? 302  TRP A CB  1 
ATOM 2413 C CG  . TRP A 1 302  ? 95.152  82.520  104.923 1.00 72.43  ? 302  TRP A CG  1 
ATOM 2414 C CD1 . TRP A 1 302  ? 96.441  82.078  104.879 1.00 85.40  ? 302  TRP A CD1 1 
ATOM 2415 C CD2 . TRP A 1 302  ? 94.866  83.035  103.608 1.00 85.28  ? 302  TRP A CD2 1 
ATOM 2416 N NE1 . TRP A 1 302  ? 96.969  82.256  103.630 1.00 94.72  ? 302  TRP A NE1 1 
ATOM 2417 C CE2 . TRP A 1 302  ? 96.025  82.839  102.828 1.00 94.01  ? 302  TRP A CE2 1 
ATOM 2418 C CE3 . TRP A 1 302  ? 93.740  83.601  103.002 1.00 92.52  ? 302  TRP A CE3 1 
ATOM 2419 C CZ2 . TRP A 1 302  ? 96.090  83.200  101.483 1.00 107.49 ? 302  TRP A CZ2 1 
ATOM 2420 C CZ3 . TRP A 1 302  ? 93.807  83.972  101.677 1.00 101.15 ? 302  TRP A CZ3 1 
ATOM 2421 C CH2 . TRP A 1 302  ? 94.968  83.771  100.928 1.00 111.87 ? 302  TRP A CH2 1 
ATOM 2422 N N   . ASP A 1 303  ? 92.556  79.840  104.760 1.00 73.22  ? 303  ASP A N   1 
ATOM 2423 C CA  . ASP A 1 303  ? 92.863  78.456  104.464 1.00 77.07  ? 303  ASP A CA  1 
ATOM 2424 C C   . ASP A 1 303  ? 94.357  78.387  104.178 1.00 84.65  ? 303  ASP A C   1 
ATOM 2425 O O   . ASP A 1 303  ? 94.909  79.298  103.569 1.00 83.71  ? 303  ASP A O   1 
ATOM 2426 C CB  . ASP A 1 303  ? 92.024  77.903  103.314 1.00 79.21  ? 303  ASP A CB  1 
ATOM 2427 C CG  . ASP A 1 303  ? 92.027  76.386  103.292 1.00 89.98  ? 303  ASP A CG  1 
ATOM 2428 O OD1 . ASP A 1 303  ? 93.130  75.806  103.369 1.00 95.28  ? 303  ASP A OD1 1 
ATOM 2429 O OD2 . ASP A 1 303  ? 90.929  75.795  103.208 1.00 100.17 ? 303  ASP A OD2 1 
ATOM 2430 N N   . GLU A 1 304  ? 95.012  77.344  104.694 1.00 95.13  ? 304  GLU A N   1 
ATOM 2431 C CA  . GLU A 1 304  ? 96.417  77.124  104.402 1.00 109.12 ? 304  GLU A CA  1 
ATOM 2432 C C   . GLU A 1 304  ? 96.560  76.721  102.937 1.00 102.52 ? 304  GLU A C   1 
ATOM 2433 O O   . GLU A 1 304  ? 97.545  77.079  102.301 1.00 98.62  ? 304  GLU A O   1 
ATOM 2434 C CB  . GLU A 1 304  ? 97.023  76.066  105.329 1.00 138.38 ? 304  GLU A CB  1 
ATOM 2435 C CG  . GLU A 1 304  ? 97.482  76.611  106.674 1.00 162.94 ? 304  GLU A CG  1 
ATOM 2436 C CD  . GLU A 1 304  ? 96.377  76.991  107.647 1.00 187.19 ? 304  GLU A CD  1 
ATOM 2437 O OE1 . GLU A 1 304  ? 95.192  76.766  107.319 1.00 197.94 ? 304  GLU A OE1 1 
ATOM 2438 O OE2 . GLU A 1 304  ? 96.701  77.517  108.733 1.00 194.47 ? 304  GLU A OE2 1 
ATOM 2439 N N   . LYS A 1 305  ? 95.561  75.991  102.417 1.00 96.83  ? 305  LYS A N   1 
ATOM 2440 C CA  . LYS A 1 305  ? 95.630  75.377  101.098 1.00 90.70  ? 305  LYS A CA  1 
ATOM 2441 C C   . LYS A 1 305  ? 96.117  76.376  100.054 1.00 76.85  ? 305  LYS A C   1 
ATOM 2442 O O   . LYS A 1 305  ? 97.096  76.125  99.355  1.00 85.68  ? 305  LYS A O   1 
ATOM 2443 C CB  . LYS A 1 305  ? 94.269  74.798  100.698 1.00 95.08  ? 305  LYS A CB  1 
ATOM 2444 C CG  . LYS A 1 305  ? 94.098  74.483  99.218  1.00 111.07 ? 305  LYS A CG  1 
ATOM 2445 C CD  . LYS A 1 305  ? 93.355  73.184  98.945  1.00 130.26 ? 305  LYS A CD  1 
ATOM 2446 C CE  . LYS A 1 305  ? 92.069  73.019  99.728  1.00 137.35 ? 305  LYS A CE  1 
ATOM 2447 N NZ  . LYS A 1 305  ? 91.150  74.160  99.521  1.00 136.45 ? 305  LYS A NZ  1 
ATOM 2448 N N   . TYR A 1 306  ? 95.435  77.509  99.954  1.00 64.82  ? 306  TYR A N   1 
ATOM 2449 C CA  . TYR A 1 306  ? 95.800  78.500  98.967  1.00 60.12  ? 306  TYR A CA  1 
ATOM 2450 C C   . TYR A 1 306  ? 96.996  79.283  99.498  1.00 59.20  ? 306  TYR A C   1 
ATOM 2451 O O   . TYR A 1 306  ? 96.956  80.510  99.541  1.00 65.49  ? 306  TYR A O   1 
ATOM 2452 C CB  . TYR A 1 306  ? 94.626  79.435  98.678  1.00 60.49  ? 306  TYR A CB  1 
ATOM 2453 C CG  . TYR A 1 306  ? 93.346  78.767  98.256  1.00 64.33  ? 306  TYR A CG  1 
ATOM 2454 C CD1 . TYR A 1 306  ? 92.643  77.942  99.113  1.00 76.29  ? 306  TYR A CD1 1 
ATOM 2455 C CD2 . TYR A 1 306  ? 92.817  78.992  97.003  1.00 73.98  ? 306  TYR A CD2 1 
ATOM 2456 C CE1 . TYR A 1 306  ? 91.450  77.350  98.732  1.00 91.47  ? 306  TYR A CE1 1 
ATOM 2457 C CE2 . TYR A 1 306  ? 91.628  78.409  96.601  1.00 87.97  ? 306  TYR A CE2 1 
ATOM 2458 C CZ  . TYR A 1 306  ? 90.937  77.584  97.469  1.00 97.10  ? 306  TYR A CZ  1 
ATOM 2459 O OH  . TYR A 1 306  ? 89.755  76.999  97.073  1.00 105.64 ? 306  TYR A OH  1 
ATOM 2460 N N   . ASP A 1 307  ? 98.047  78.577  99.926  1.00 63.04  ? 307  ASP A N   1 
ATOM 2461 C CA  . ASP A 1 307  ? 99.244  79.254  100.394 1.00 83.94  ? 307  ASP A CA  1 
ATOM 2462 C C   . ASP A 1 307  ? 100.486 78.660  99.727  1.00 88.50  ? 307  ASP A C   1 
ATOM 2463 O O   . ASP A 1 307  ? 101.604 78.894  100.185 1.00 87.79  ? 307  ASP A O   1 
ATOM 2464 C CB  . ASP A 1 307  ? 99.342  79.204  101.923 1.00 110.52 ? 307  ASP A CB  1 
ATOM 2465 C CG  . ASP A 1 307  ? 100.055 80.397  102.542 1.00 135.79 ? 307  ASP A CG  1 
ATOM 2466 O OD1 . ASP A 1 307  ? 101.249 80.605  102.227 1.00 142.36 ? 307  ASP A OD1 1 
ATOM 2467 O OD2 . ASP A 1 307  ? 99.407  81.112  103.343 1.00 151.00 ? 307  ASP A OD2 1 
ATOM 2468 N N   . ALA A 1 308  ? 100.287 77.921  98.628  1.00 96.62  ? 308  ALA A N   1 
ATOM 2469 C CA  . ALA A 1 308  ? 101.387 77.288  97.915  1.00 105.08 ? 308  ALA A CA  1 
ATOM 2470 C C   . ALA A 1 308  ? 101.115 77.330  96.414  1.00 105.72 ? 308  ALA A C   1 
ATOM 2471 O O   . ALA A 1 308  ? 99.985  77.108  95.975  1.00 105.61 ? 308  ALA A O   1 
ATOM 2472 C CB  . ALA A 1 308  ? 101.561 75.866  98.397  1.00 113.09 ? 308  ALA A CB  1 
ATOM 2473 N N   . VAL A 1 309  ? 102.171 77.585  95.629  1.00 96.42  ? 309  VAL A N   1 
ATOM 2474 C CA  . VAL A 1 309  ? 102.048 77.629  94.181  1.00 85.74  ? 309  VAL A CA  1 
ATOM 2475 C C   . VAL A 1 309  ? 101.291 76.391  93.737  1.00 79.05  ? 309  VAL A C   1 
ATOM 2476 O O   . VAL A 1 309  ? 101.628 75.281  94.135  1.00 86.44  ? 309  VAL A O   1 
ATOM 2477 C CB  . VAL A 1 309  ? 103.407 77.689  93.465  1.00 92.40  ? 309  VAL A CB  1 
ATOM 2478 C CG1 . VAL A 1 309  ? 103.220 77.887  91.967  1.00 92.54  ? 309  VAL A CG1 1 
ATOM 2479 C CG2 . VAL A 1 309  ? 104.319 78.762  94.047  1.00 103.61 ? 309  VAL A CG2 1 
ATOM 2480 N N   . ASP A 1 310  ? 100.257 76.595  92.930  1.00 86.86  ? 310  ASP A N   1 
ATOM 2481 C CA  . ASP A 1 310  ? 99.557  75.477  92.335  1.00 110.57 ? 310  ASP A CA  1 
ATOM 2482 C C   . ASP A 1 310  ? 100.044 75.361  90.895  1.00 115.36 ? 310  ASP A C   1 
ATOM 2483 O O   . ASP A 1 310  ? 99.751  76.231  90.083  1.00 130.07 ? 310  ASP A O   1 
ATOM 2484 C CB  . ASP A 1 310  ? 98.043  75.662  92.453  1.00 128.34 ? 310  ASP A CB  1 
ATOM 2485 C CG  . ASP A 1 310  ? 97.241  74.519  91.852  1.00 147.27 ? 310  ASP A CG  1 
ATOM 2486 O OD1 . ASP A 1 310  ? 97.864  73.630  91.227  1.00 155.60 ? 310  ASP A OD1 1 
ATOM 2487 O OD2 . ASP A 1 310  ? 96.002  74.522  92.018  1.00 150.33 ? 310  ASP A OD2 1 
ATOM 2488 N N   . MET A 1 311  ? 100.795 74.297  90.586  1.00 104.81 ? 311  MET A N   1 
ATOM 2489 C CA  . MET A 1 311  ? 101.396 74.175  89.270  1.00 101.69 ? 311  MET A CA  1 
ATOM 2490 C C   . MET A 1 311  ? 100.317 73.952  88.214  1.00 97.81  ? 311  MET A C   1 
ATOM 2491 O O   . MET A 1 311  ? 100.420 74.493  87.115  1.00 106.50 ? 311  MET A O   1 
ATOM 2492 C CB  . MET A 1 311  ? 102.424 73.043  89.207  1.00 114.19 ? 311  MET A CB  1 
ATOM 2493 C CG  . MET A 1 311  ? 103.849 73.544  89.321  1.00 126.39 ? 311  MET A CG  1 
ATOM 2494 S SD  . MET A 1 311  ? 104.104 74.452  90.857  1.00 145.61 ? 311  MET A SD  1 
ATOM 2495 C CE  . MET A 1 311  ? 105.379 75.607  90.360  1.00 143.29 ? 311  MET A CE  1 
ATOM 2496 N N   . GLN A 1 312  ? 99.272  73.189  88.540  1.00 91.92  ? 312  GLN A N   1 
ATOM 2497 C CA  . GLN A 1 312  ? 98.275  72.870  87.530  1.00 98.61  ? 312  GLN A CA  1 
ATOM 2498 C C   . GLN A 1 312  ? 97.777  74.155  86.877  1.00 95.76  ? 312  GLN A C   1 
ATOM 2499 O O   . GLN A 1 312  ? 97.601  74.201  85.662  1.00 108.55 ? 312  GLN A O   1 
ATOM 2500 C CB  . GLN A 1 312  ? 97.101  72.071  88.098  1.00 113.76 ? 312  GLN A CB  1 
ATOM 2501 C CG  . GLN A 1 312  ? 97.116  70.603  87.695  1.00 134.61 ? 312  GLN A CG  1 
ATOM 2502 C CD  . GLN A 1 312  ? 98.387  69.891  88.095  1.00 156.96 ? 312  GLN A CD  1 
ATOM 2503 O OE1 . GLN A 1 312  ? 98.731  69.804  89.273  1.00 167.22 ? 312  GLN A OE1 1 
ATOM 2504 N NE2 . GLN A 1 312  ? 99.099  69.370  87.108  1.00 166.26 ? 312  GLN A NE2 1 
ATOM 2505 N N   . ASP A 1 313  ? 97.588  75.203  87.681  1.00 89.86  ? 313  ASP A N   1 
ATOM 2506 C CA  . ASP A 1 313  ? 96.922  76.401  87.205  1.00 94.75  ? 313  ASP A CA  1 
ATOM 2507 C C   . ASP A 1 313  ? 97.916  77.440  86.698  1.00 77.22  ? 313  ASP A C   1 
ATOM 2508 O O   . ASP A 1 313  ? 97.491  78.497  86.255  1.00 87.61  ? 313  ASP A O   1 
ATOM 2509 C CB  . ASP A 1 313  ? 96.007  76.978  88.289  1.00 117.12 ? 313  ASP A CB  1 
ATOM 2510 C CG  . ASP A 1 313  ? 94.693  76.225  88.434  1.00 133.36 ? 313  ASP A CG  1 
ATOM 2511 O OD1 . ASP A 1 313  ? 94.556  75.149  87.809  1.00 139.60 ? 313  ASP A OD1 1 
ATOM 2512 O OD2 . ASP A 1 313  ? 93.809  76.725  89.163  1.00 138.80 ? 313  ASP A OD2 1 
ATOM 2513 N N   . MET A 1 314  ? 99.219  77.149  86.723  1.00 63.60  ? 314  MET A N   1 
ATOM 2514 C CA  . MET A 1 314  ? 100.189 78.072  86.154  1.00 66.27  ? 314  MET A CA  1 
ATOM 2515 C C   . MET A 1 314  ? 100.491 77.696  84.701  1.00 77.24  ? 314  MET A C   1 
ATOM 2516 O O   . MET A 1 314  ? 101.353 78.312  84.067  1.00 75.28  ? 314  MET A O   1 
ATOM 2517 C CB  . MET A 1 314  ? 101.483 78.064  86.963  1.00 67.89  ? 314  MET A CB  1 
ATOM 2518 C CG  . MET A 1 314  ? 101.272 78.514  88.374  1.00 73.37  ? 314  MET A CG  1 
ATOM 2519 S SD  . MET A 1 314  ? 100.613 80.186  88.541  1.00 91.08  ? 314  MET A SD  1 
ATOM 2520 C CE  . MET A 1 314  ? 101.450 81.044  87.212  1.00 89.58  ? 314  MET A CE  1 
ATOM 2521 N N   . ASN A 1 315  ? 99.724  76.729  84.170  1.00 86.05  ? 315  ASN A N   1 
ATOM 2522 C CA  . ASN A 1 315  ? 99.918  76.204  82.827  1.00 85.30  ? 315  ASN A CA  1 
ATOM 2523 C C   . ASN A 1 315  ? 99.298  77.091  81.752  1.00 77.18  ? 315  ASN A C   1 
ATOM 2524 O O   . ASN A 1 315  ? 99.819  77.120  80.642  1.00 86.95  ? 315  ASN A O   1 
ATOM 2525 C CB  . ASN A 1 315  ? 99.344  74.797  82.655  1.00 93.37  ? 315  ASN A CB  1 
ATOM 2526 C CG  . ASN A 1 315  ? 100.419 73.732  82.621  1.00 115.74 ? 315  ASN A CG  1 
ATOM 2527 O OD1 . ASN A 1 315  ? 101.606 74.037  82.507  1.00 118.76 ? 315  ASN A OD1 1 
ATOM 2528 N ND2 . ASN A 1 315  ? 100.012 72.475  82.690  1.00 133.23 ? 315  ASN A ND2 1 
ATOM 2529 N N   . ASN A 1 316  ? 98.177  77.765  82.052  1.00 65.27  ? 316  ASN A N   1 
ATOM 2530 C CA  . ASN A 1 316  ? 97.441  78.528  81.049  1.00 62.78  ? 316  ASN A CA  1 
ATOM 2531 C C   . ASN A 1 316  ? 98.279  79.713  80.560  1.00 62.79  ? 316  ASN A C   1 
ATOM 2532 O O   . ASN A 1 316  ? 99.320  80.007  81.136  1.00 67.02  ? 316  ASN A O   1 
ATOM 2533 C CB  . ASN A 1 316  ? 96.075  78.977  81.576  1.00 64.94  ? 316  ASN A CB  1 
ATOM 2534 C CG  . ASN A 1 316  ? 95.147  77.820  81.884  1.00 78.38  ? 316  ASN A CG  1 
ATOM 2535 O OD1 . ASN A 1 316  ? 94.005  78.014  82.298  1.00 80.80  ? 316  ASN A OD1 1 
ATOM 2536 N ND2 . ASN A 1 316  ? 95.619  76.603  81.680  1.00 91.89  ? 316  ASN A ND2 1 
ATOM 2537 N N   . PRO A 1 317  ? 97.878  80.410  79.467  1.00 56.76  ? 317  PRO A N   1 
ATOM 2538 C CA  . PRO A 1 317  ? 98.619  81.557  78.924  1.00 50.48  ? 317  PRO A CA  1 
ATOM 2539 C C   . PRO A 1 317  ? 98.623  82.825  79.778  1.00 54.71  ? 317  PRO A C   1 
ATOM 2540 O O   . PRO A 1 317  ? 97.682  83.053  80.541  1.00 65.69  ? 317  PRO A O   1 
ATOM 2541 C CB  . PRO A 1 317  ? 97.826  81.923  77.659  1.00 53.81  ? 317  PRO A CB  1 
ATOM 2542 C CG  . PRO A 1 317  ? 97.046  80.674  77.315  1.00 57.75  ? 317  PRO A CG  1 
ATOM 2543 C CD  . PRO A 1 317  ? 96.690  80.088  78.661  1.00 57.02  ? 317  PRO A CD  1 
ATOM 2544 N N   . LEU A 1 318  ? 99.629  83.690  79.580  1.00 46.96  ? 318  LEU A N   1 
ATOM 2545 C CA  . LEU A 1 318  ? 99.848  84.869  80.412  1.00 40.88  ? 318  LEU A CA  1 
ATOM 2546 C C   . LEU A 1 318  ? 98.584  85.712  80.501  1.00 44.24  ? 318  LEU A C   1 
ATOM 2547 O O   . LEU A 1 318  ? 98.229  86.197  81.572  1.00 50.68  ? 318  LEU A O   1 
ATOM 2548 C CB  . LEU A 1 318  ? 100.973 85.715  79.830  1.00 41.13  ? 318  LEU A CB  1 
ATOM 2549 C CG  . LEU A 1 318  ? 101.947 86.271  80.864  1.00 51.69  ? 318  LEU A CG  1 
ATOM 2550 C CD1 . LEU A 1 318  ? 103.152 85.348  81.020  1.00 54.61  ? 318  LEU A CD1 1 
ATOM 2551 C CD2 . LEU A 1 318  ? 102.388 87.687  80.499  1.00 61.41  ? 318  LEU A CD2 1 
ATOM 2552 N N   . SER A 1 319  ? 97.894  85.857  79.371  1.00 49.77  ? 319  SER A N   1 
ATOM 2553 C CA  . SER A 1 319  ? 96.742  86.735  79.291  1.00 57.14  ? 319  SER A CA  1 
ATOM 2554 C C   . SER A 1 319  ? 95.708  86.382  80.349  1.00 51.61  ? 319  SER A C   1 
ATOM 2555 O O   . SER A 1 319  ? 95.065  87.275  80.887  1.00 63.83  ? 319  SER A O   1 
ATOM 2556 C CB  . SER A 1 319  ? 96.078  86.678  77.955  1.00 69.18  ? 319  SER A CB  1 
ATOM 2557 O OG  . SER A 1 319  ? 94.848  85.974  78.065  1.00 71.36  ? 319  SER A OG  1 
ATOM 2558 N N   . HIS A 1 320  ? 95.516  85.094  80.613  1.00 46.96  ? 320  HIS A N   1 
ATOM 2559 C CA  . HIS A 1 320  ? 94.443  84.701  81.505  1.00 58.92  ? 320  HIS A CA  1 
ATOM 2560 C C   . HIS A 1 320  ? 94.817  84.898  82.978  1.00 57.94  ? 320  HIS A C   1 
ATOM 2561 O O   . HIS A 1 320  ? 93.989  84.640  83.842  1.00 62.85  ? 320  HIS A O   1 
ATOM 2562 C CB  . HIS A 1 320  ? 93.984  83.275  81.199  1.00 71.96  ? 320  HIS A CB  1 
ATOM 2563 C CG  . HIS A 1 320  ? 93.553  83.117  79.791  1.00 88.86  ? 320  HIS A CG  1 
ATOM 2564 N ND1 . HIS A 1 320  ? 94.195  82.269  78.919  1.00 106.91 ? 320  HIS A ND1 1 
ATOM 2565 C CD2 . HIS A 1 320  ? 92.587  83.712  79.091  1.00 111.96 ? 320  HIS A CD2 1 
ATOM 2566 C CE1 . HIS A 1 320  ? 93.608  82.340  77.732  1.00 128.53 ? 320  HIS A CE1 1 
ATOM 2567 N NE2 . HIS A 1 320  ? 92.629  83.210  77.812  1.00 131.43 ? 320  HIS A NE2 1 
ATOM 2568 N N   . TYR A 1 321  ? 96.046  85.340  83.271  1.00 55.43  ? 321  TYR A N   1 
ATOM 2569 C CA  . TYR A 1 321  ? 96.470  85.620  84.638  1.00 57.69  ? 321  TYR A CA  1 
ATOM 2570 C C   . TYR A 1 321  ? 96.371  87.108  84.962  1.00 54.39  ? 321  TYR A C   1 
ATOM 2571 O O   . TYR A 1 321  ? 96.682  87.936  84.113  1.00 61.00  ? 321  TYR A O   1 
ATOM 2572 C CB  . TYR A 1 321  ? 97.909  85.143  84.850  1.00 67.67  ? 321  TYR A CB  1 
ATOM 2573 C CG  . TYR A 1 321  ? 98.027  83.651  84.697  1.00 81.77  ? 321  TYR A CG  1 
ATOM 2574 C CD1 . TYR A 1 321  ? 97.578  82.806  85.691  1.00 94.06  ? 321  TYR A CD1 1 
ATOM 2575 C CD2 . TYR A 1 321  ? 98.464  83.083  83.517  1.00 85.75  ? 321  TYR A CD2 1 
ATOM 2576 C CE1 . TYR A 1 321  ? 97.623  81.431  85.545  1.00 99.13  ? 321  TYR A CE1 1 
ATOM 2577 C CE2 . TYR A 1 321  ? 98.508  81.711  83.352  1.00 89.74  ? 321  TYR A CE2 1 
ATOM 2578 C CZ  . TYR A 1 321  ? 98.084  80.879  84.366  1.00 98.93  ? 321  TYR A CZ  1 
ATOM 2579 O OH  . TYR A 1 321  ? 98.136  79.521  84.187  1.00 114.05 ? 321  TYR A OH  1 
ATOM 2580 N N   . TRP A 1 322  ? 95.949  87.412  86.206  1.00 45.00  ? 322  TRP A N   1 
ATOM 2581 C CA  . TRP A 1 322  ? 95.892  88.759  86.761  1.00 32.86  ? 322  TRP A CA  1 
ATOM 2582 C C   . TRP A 1 322  ? 97.259  89.127  87.299  1.00 25.50  ? 322  TRP A C   1 
ATOM 2583 O O   . TRP A 1 322  ? 97.470  89.094  88.490  1.00 28.08  ? 322  TRP A O   1 
ATOM 2584 C CB  . TRP A 1 322  ? 94.883  88.872  87.916  1.00 33.05  ? 322  TRP A CB  1 
ATOM 2585 C CG  . TRP A 1 322  ? 93.433  88.902  87.566  1.00 37.91  ? 322  TRP A CG  1 
ATOM 2586 C CD1 . TRP A 1 322  ? 92.839  89.592  86.555  1.00 48.54  ? 322  TRP A CD1 1 
ATOM 2587 C CD2 . TRP A 1 322  ? 92.365  88.293  88.300  1.00 40.08  ? 322  TRP A CD2 1 
ATOM 2588 N NE1 . TRP A 1 322  ? 91.481  89.419  86.584  1.00 51.03  ? 322  TRP A NE1 1 
ATOM 2589 C CE2 . TRP A 1 322  ? 91.161  88.632  87.654  1.00 43.20  ? 322  TRP A CE2 1 
ATOM 2590 C CE3 . TRP A 1 322  ? 92.310  87.494  89.437  1.00 49.61  ? 322  TRP A CE3 1 
ATOM 2591 C CZ2 . TRP A 1 322  ? 89.919  88.173  88.078  1.00 44.91  ? 322  TRP A CZ2 1 
ATOM 2592 C CZ3 . TRP A 1 322  ? 91.082  87.049  89.872  1.00 55.77  ? 322  TRP A CZ3 1 
ATOM 2593 C CH2 . TRP A 1 322  ? 89.905  87.385  89.200  1.00 51.82  ? 322  TRP A CH2 1 
ATOM 2594 N N   . ILE A 1 323  ? 98.162  89.562  86.455  1.00 26.90  ? 323  ILE A N   1 
ATOM 2595 C CA  . ILE A 1 323  ? 99.508  89.834  86.904  1.00 35.50  ? 323  ILE A CA  1 
ATOM 2596 C C   . ILE A 1 323  ? 99.508  91.017  87.872  1.00 32.33  ? 323  ILE A C   1 
ATOM 2597 O O   . ILE A 1 323  ? 98.853  92.022  87.629  1.00 35.72  ? 323  ILE A O   1 
ATOM 2598 C CB  . ILE A 1 323  ? 100.401 90.120  85.686  1.00 58.01  ? 323  ILE A CB  1 
ATOM 2599 C CG1 . ILE A 1 323  ? 100.150 89.118  84.546  1.00 74.67  ? 323  ILE A CG1 1 
ATOM 2600 C CG2 . ILE A 1 323  ? 101.859 90.158  86.115  1.00 62.26  ? 323  ILE A CG2 1 
ATOM 2601 C CD1 . ILE A 1 323  ? 100.561 89.601  83.166  1.00 75.06  ? 323  ILE A CD1 1 
ATOM 2602 N N   . SER A 1 324  ? 100.252 90.902  88.973  1.00 31.57  ? 324  SER A N   1 
ATOM 2603 C CA  . SER A 1 324  ? 100.400 91.992  89.919  1.00 33.65  ? 324  SER A CA  1 
ATOM 2604 C C   . SER A 1 324  ? 101.127 93.142  89.242  1.00 36.27  ? 324  SER A C   1 
ATOM 2605 O O   . SER A 1 324  ? 101.876 92.903  88.302  1.00 38.68  ? 324  SER A O   1 
ATOM 2606 C CB  . SER A 1 324  ? 101.168 91.543  91.127  1.00 36.69  ? 324  SER A CB  1 
ATOM 2607 O OG  . SER A 1 324  ? 101.332 92.613  92.040  1.00 40.21  ? 324  SER A OG  1 
ATOM 2608 N N   . SER A 1 325  ? 100.954 94.375  89.735  1.00 38.97  ? 325  SER A N   1 
ATOM 2609 C CA  . SER A 1 325  ? 101.544 95.515  89.047  1.00 44.83  ? 325  SER A CA  1 
ATOM 2610 C C   . SER A 1 325  ? 101.809 96.670  89.992  1.00 45.39  ? 325  SER A C   1 
ATOM 2611 O O   . SER A 1 325  ? 101.054 96.878  90.930  1.00 54.08  ? 325  SER A O   1 
ATOM 2612 C CB  . SER A 1 325  ? 100.660 95.983  87.911  1.00 53.90  ? 325  SER A CB  1 
ATOM 2613 O OG  . SER A 1 325  ? 100.415 94.920  87.000  1.00 62.55  ? 325  SER A OG  1 
ATOM 2614 N N   . SER A 1 326  ? 102.849 97.442  89.680  1.00 49.87  ? 326  SER A N   1 
ATOM 2615 C CA  . SER A 1 326  ? 103.163 98.679  90.373  1.00 60.54  ? 326  SER A CA  1 
ATOM 2616 C C   . SER A 1 326  ? 103.175 99.815  89.358  1.00 66.88  ? 326  SER A C   1 
ATOM 2617 O O   . SER A 1 326  ? 103.726 99.621  88.274  1.00 72.04  ? 326  SER A O   1 
ATOM 2618 C CB  . SER A 1 326  ? 104.505 98.546  91.059  1.00 60.74  ? 326  SER A CB  1 
ATOM 2619 O OG  . SER A 1 326  ? 104.904 99.758  91.685  1.00 57.98  ? 326  SER A OG  1 
ATOM 2620 N N   . HIS A 1 327  ? 102.585 100.975 89.699  1.00 71.75  ? 327  HIS A N   1 
ATOM 2621 C CA  . HIS A 1 327  ? 102.721 102.159 88.860  1.00 83.80  ? 327  HIS A CA  1 
ATOM 2622 C C   . HIS A 1 327  ? 104.175 102.606 88.880  1.00 76.69  ? 327  HIS A C   1 
ATOM 2623 O O   . HIS A 1 327  ? 105.054 101.829 88.533  1.00 79.55  ? 327  HIS A O   1 
ATOM 2624 C CB  . HIS A 1 327  ? 101.848 103.330 89.320  1.00 90.88  ? 327  HIS A CB  1 
ATOM 2625 C CG  . HIS A 1 327  ? 101.978 104.558 88.463  1.00 95.60  ? 327  HIS A CG  1 
ATOM 2626 N ND1 . HIS A 1 327  ? 101.428 105.771 88.811  1.00 93.17  ? 327  HIS A ND1 1 
ATOM 2627 C CD2 . HIS A 1 327  ? 102.580 104.758 87.273  1.00 115.00 ? 327  HIS A CD2 1 
ATOM 2628 C CE1 . HIS A 1 327  ? 101.672 106.658 87.862  1.00 112.59 ? 327  HIS A CE1 1 
ATOM 2629 N NE2 . HIS A 1 327  ? 102.379 106.068 86.920  1.00 124.95 ? 327  HIS A NE2 1 
ATOM 2630 N N   . ASN A 1 328  ? 104.442 103.837 89.312  1.00 69.68  ? 328  ASN A N   1 
ATOM 2631 C CA  . ASN A 1 328  ? 105.819 104.184 89.575  1.00 80.46  ? 328  ASN A CA  1 
ATOM 2632 C C   . ASN A 1 328  ? 106.237 103.267 90.713  1.00 72.36  ? 328  ASN A C   1 
ATOM 2633 O O   . ASN A 1 328  ? 105.433 103.002 91.606  1.00 80.54  ? 328  ASN A O   1 
ATOM 2634 C CB  . ASN A 1 328  ? 105.992 105.671 89.872  1.00 100.20 ? 328  ASN A CB  1 
ATOM 2635 C CG  . ASN A 1 328  ? 105.474 106.546 88.752  1.00 115.30 ? 328  ASN A CG  1 
ATOM 2636 O OD1 . ASN A 1 328  ? 105.944 106.456 87.622  1.00 115.12 ? 328  ASN A OD1 1 
ATOM 2637 N ND2 . ASN A 1 328  ? 104.520 107.407 89.056  1.00 119.88 ? 328  ASN A ND2 1 
ATOM 2638 N N   . THR A 1 329  ? 107.419 102.666 90.602  1.00 55.03  ? 329  THR A N   1 
ATOM 2639 C CA  . THR A 1 329  ? 107.854 101.766 91.641  1.00 47.77  ? 329  THR A CA  1 
ATOM 2640 C C   . THR A 1 329  ? 108.977 102.437 92.397  1.00 49.32  ? 329  THR A C   1 
ATOM 2641 O O   . THR A 1 329  ? 109.084 102.300 93.611  1.00 64.75  ? 329  THR A O   1 
ATOM 2642 C CB  . THR A 1 329  ? 108.232 100.393 91.092  1.00 46.66  ? 329  THR A CB  1 
ATOM 2643 O OG1 . THR A 1 329  ? 107.098 99.897  90.384  1.00 39.99  ? 329  THR A OG1 1 
ATOM 2644 C CG2 . THR A 1 329  ? 108.606 99.411  92.184  1.00 57.11  ? 329  THR A CG2 1 
ATOM 2645 N N   . TYR A 1 330  ? 109.787 103.179 91.660  1.00 49.13  ? 330  TYR A N   1 
ATOM 2646 C CA  . TYR A 1 330  ? 110.946 103.854 92.213  1.00 60.67  ? 330  TYR A CA  1 
ATOM 2647 C C   . TYR A 1 330  ? 110.567 104.844 93.324  1.00 71.85  ? 330  TYR A C   1 
ATOM 2648 O O   . TYR A 1 330  ? 111.286 104.957 94.313  1.00 68.48  ? 330  TYR A O   1 
ATOM 2649 C CB  . TYR A 1 330  ? 111.753 104.477 91.072  1.00 61.73  ? 330  TYR A CB  1 
ATOM 2650 C CG  . TYR A 1 330  ? 111.023 105.429 90.155  1.00 66.01  ? 330  TYR A CG  1 
ATOM 2651 C CD1 . TYR A 1 330  ? 109.936 105.031 89.383  1.00 71.02  ? 330  TYR A CD1 1 
ATOM 2652 C CD2 . TYR A 1 330  ? 111.464 106.735 90.010  1.00 71.32  ? 330  TYR A CD2 1 
ATOM 2653 C CE1 . TYR A 1 330  ? 109.278 105.908 88.536  1.00 78.91  ? 330  TYR A CE1 1 
ATOM 2654 C CE2 . TYR A 1 330  ? 110.828 107.621 89.159  1.00 79.68  ? 330  TYR A CE2 1 
ATOM 2655 C CZ  . TYR A 1 330  ? 109.729 107.210 88.424  1.00 86.59  ? 330  TYR A CZ  1 
ATOM 2656 O OH  . TYR A 1 330  ? 109.097 108.076 87.571  1.00 97.90  ? 330  TYR A OH  1 
ATOM 2657 N N   . LEU A 1 331  ? 109.442 105.557 93.190  1.00 81.50  ? 331  LEU A N   1 
ATOM 2658 C CA  . LEU A 1 331  ? 109.077 106.586 94.160  1.00 88.17  ? 331  LEU A CA  1 
ATOM 2659 C C   . LEU A 1 331  ? 108.524 105.971 95.447  1.00 89.94  ? 331  LEU A C   1 
ATOM 2660 O O   . LEU A 1 331  ? 107.396 105.484 95.460  1.00 96.45  ? 331  LEU A O   1 
ATOM 2661 C CB  . LEU A 1 331  ? 108.028 107.507 93.527  1.00 95.98  ? 331  LEU A CB  1 
ATOM 2662 C CG  . LEU A 1 331  ? 108.467 108.234 92.256  1.00 113.38 ? 331  LEU A CG  1 
ATOM 2663 C CD1 . LEU A 1 331  ? 107.481 109.326 91.882  1.00 118.33 ? 331  LEU A CD1 1 
ATOM 2664 C CD2 . LEU A 1 331  ? 109.862 108.818 92.407  1.00 117.56 ? 331  LEU A CD2 1 
ATOM 2665 N N   . THR A 1 332  ? 109.303 106.008 96.535  1.00 82.09  ? 332  THR A N   1 
ATOM 2666 C CA  . THR A 1 332  ? 108.768 105.692 97.849  1.00 75.59  ? 332  THR A CA  1 
ATOM 2667 C C   . THR A 1 332  ? 108.040 106.915 98.384  1.00 79.59  ? 332  THR A C   1 
ATOM 2668 O O   . THR A 1 332  ? 108.702 107.884 98.738  1.00 88.90  ? 332  THR A O   1 
ATOM 2669 C CB  . THR A 1 332  ? 109.883 105.394 98.850  1.00 79.20  ? 332  THR A CB  1 
ATOM 2670 O OG1 . THR A 1 332  ? 110.795 106.485 98.735  1.00 68.94  ? 332  THR A OG1 1 
ATOM 2671 C CG2 . THR A 1 332  ? 110.585 104.077 98.601  1.00 90.10  ? 332  THR A CG2 1 
ATOM 2672 N N   . GLY A 1 333  ? 106.704 106.893 98.399  1.00 78.89  ? 333  GLY A N   1 
ATOM 2673 C CA  . GLY A 1 333  ? 105.919 108.022 98.890  1.00 86.53  ? 333  GLY A CA  1 
ATOM 2674 C C   . GLY A 1 333  ? 105.242 108.830 97.779  1.00 87.56  ? 333  GLY A C   1 
ATOM 2675 O O   . GLY A 1 333  ? 104.879 108.271 96.749  1.00 88.89  ? 333  GLY A O   1 
ATOM 2676 N N   . ASP A 1 334  ? 105.068 110.142 98.012  1.00 89.29  ? 334  ASP A N   1 
ATOM 2677 C CA  . ASP A 1 334  ? 104.319 111.032 97.130  1.00 96.30  ? 334  ASP A CA  1 
ATOM 2678 C C   . ASP A 1 334  ? 105.085 111.289 95.834  1.00 84.06  ? 334  ASP A C   1 
ATOM 2679 O O   . ASP A 1 334  ? 106.300 111.459 95.871  1.00 79.85  ? 334  ASP A O   1 
ATOM 2680 C CB  . ASP A 1 334  ? 104.061 112.381 97.805  1.00 124.98 ? 334  ASP A CB  1 
ATOM 2681 C CG  . ASP A 1 334  ? 105.337 113.113 98.200  1.00 146.33 ? 334  ASP A CG  1 
ATOM 2682 O OD1 . ASP A 1 334  ? 106.100 112.547 99.012  1.00 149.65 ? 334  ASP A OD1 1 
ATOM 2683 O OD2 . ASP A 1 334  ? 105.561 114.237 97.691  1.00 157.28 ? 334  ASP A OD2 1 
ATOM 2684 N N   . GLN A 1 335  ? 104.372 111.408 94.700  1.00 71.30  ? 335  GLN A N   1 
ATOM 2685 C CA  . GLN A 1 335  ? 105.031 111.434 93.402  1.00 61.26  ? 335  GLN A CA  1 
ATOM 2686 C C   . GLN A 1 335  ? 105.766 112.749 93.154  1.00 58.22  ? 335  GLN A C   1 
ATOM 2687 O O   . GLN A 1 335  ? 106.573 112.811 92.232  1.00 62.62  ? 335  GLN A O   1 
ATOM 2688 C CB  . GLN A 1 335  ? 104.054 111.158 92.262  1.00 55.98  ? 335  GLN A CB  1 
ATOM 2689 C CG  . GLN A 1 335  ? 103.513 109.735 92.269  1.00 60.58  ? 335  GLN A CG  1 
ATOM 2690 C CD  . GLN A 1 335  ? 102.643 109.499 91.063  1.00 81.58  ? 335  GLN A CD  1 
ATOM 2691 O OE1 . GLN A 1 335  ? 102.481 110.378 90.217  1.00 96.58  ? 335  GLN A OE1 1 
ATOM 2692 N NE2 . GLN A 1 335  ? 102.059 108.315 90.979  1.00 95.24  ? 335  GLN A NE2 1 
ATOM 2693 N N   . LEU A 1 336  ? 105.517 113.786 93.964  1.00 58.88  ? 336  LEU A N   1 
ATOM 2694 C CA  . LEU A 1 336  ? 106.108 115.094 93.716  1.00 63.49  ? 336  LEU A CA  1 
ATOM 2695 C C   . LEU A 1 336  ? 107.461 115.246 94.404  1.00 66.24  ? 336  LEU A C   1 
ATOM 2696 O O   . LEU A 1 336  ? 108.409 115.671 93.763  1.00 72.02  ? 336  LEU A O   1 
ATOM 2697 C CB  . LEU A 1 336  ? 105.134 116.177 94.172  1.00 72.11  ? 336  LEU A CB  1 
ATOM 2698 C CG  . LEU A 1 336  ? 103.774 116.130 93.478  1.00 85.98  ? 336  LEU A CG  1 
ATOM 2699 C CD1 . LEU A 1 336  ? 102.961 117.378 93.787  1.00 96.72  ? 336  LEU A CD1 1 
ATOM 2700 C CD2 . LEU A 1 336  ? 103.936 115.945 91.972  1.00 86.95  ? 336  LEU A CD2 1 
ATOM 2701 N N   . ARG A 1 337  ? 107.572 114.929 95.696  1.00 72.23  ? 337  ARG A N   1 
ATOM 2702 C CA  . ARG A 1 337  ? 108.778 115.275 96.438  1.00 80.75  ? 337  ARG A CA  1 
ATOM 2703 C C   . ARG A 1 337  ? 109.505 114.029 96.954  1.00 82.01  ? 337  ARG A C   1 
ATOM 2704 O O   . ARG A 1 337  ? 110.522 114.167 97.635  1.00 81.58  ? 337  ARG A O   1 
ATOM 2705 C CB  . ARG A 1 337  ? 108.366 116.236 97.558  1.00 94.20  ? 337  ARG A CB  1 
ATOM 2706 C CG  . ARG A 1 337  ? 109.488 116.804 98.417  1.00 101.62 ? 337  ARG A CG  1 
ATOM 2707 C CD  . ARG A 1 337  ? 108.851 117.619 99.530  1.00 105.33 ? 337  ARG A CD  1 
ATOM 2708 N NE  . ARG A 1 337  ? 107.887 116.815 100.283 1.00 116.46 ? 337  ARG A NE  1 
ATOM 2709 C CZ  . ARG A 1 337  ? 106.557 116.938 100.233 1.00 127.70 ? 337  ARG A CZ  1 
ATOM 2710 N NH1 . ARG A 1 337  ? 105.796 116.093 100.907 1.00 130.53 ? 337  ARG A NH1 1 
ATOM 2711 N NH2 . ARG A 1 337  ? 105.984 117.886 99.508  1.00 130.32 ? 337  ARG A NH2 1 
ATOM 2712 N N   . SER A 1 338  ? 109.031 112.825 96.583  1.00 83.29  ? 338  SER A N   1 
ATOM 2713 C CA  . SER A 1 338  ? 109.505 111.566 97.156  1.00 80.48  ? 338  SER A CA  1 
ATOM 2714 C C   . SER A 1 338  ? 110.989 111.326 96.902  1.00 82.27  ? 338  SER A C   1 
ATOM 2715 O O   . SER A 1 338  ? 111.509 111.648 95.838  1.00 98.04  ? 338  SER A O   1 
ATOM 2716 C CB  . SER A 1 338  ? 108.739 110.412 96.601  1.00 79.67  ? 338  SER A CB  1 
ATOM 2717 O OG  . SER A 1 338  ? 109.307 109.169 96.995  1.00 88.60  ? 338  SER A OG  1 
ATOM 2718 N N   . GLU A 1 339  ? 111.647 110.675 97.866  1.00 84.05  ? 339  GLU A N   1 
ATOM 2719 C CA  . GLU A 1 339  ? 112.993 110.171 97.658  1.00 94.07  ? 339  GLU A CA  1 
ATOM 2720 C C   . GLU A 1 339  ? 112.862 108.782 97.047  1.00 98.83  ? 339  GLU A C   1 
ATOM 2721 O O   . GLU A 1 339  ? 112.228 107.918 97.643  1.00 105.47 ? 339  GLU A O   1 
ATOM 2722 C CB  . GLU A 1 339  ? 113.774 110.127 98.972  1.00 109.94 ? 339  GLU A CB  1 
ATOM 2723 C CG  . GLU A 1 339  ? 115.201 109.629 98.809  1.00 122.87 ? 339  GLU A CG  1 
ATOM 2724 C CD  . GLU A 1 339  ? 116.036 109.624 100.080 1.00 145.50 ? 339  GLU A CD  1 
ATOM 2725 O OE1 . GLU A 1 339  ? 117.206 109.196 100.010 1.00 157.46 ? 339  GLU A OE1 1 
ATOM 2726 O OE2 . GLU A 1 339  ? 115.520 110.049 101.136 1.00 156.65 ? 339  GLU A OE2 1 
ATOM 2727 N N   . SER A 1 340  ? 113.419 108.594 95.846  1.00 98.02  ? 340  SER A N   1 
ATOM 2728 C CA  . SER A 1 340  ? 113.334 107.320 95.149  1.00 91.96  ? 340  SER A CA  1 
ATOM 2729 C C   . SER A 1 340  ? 114.655 106.580 95.328  1.00 94.76  ? 340  SER A C   1 
ATOM 2730 O O   . SER A 1 340  ? 115.718 107.196 95.291  1.00 89.00  ? 340  SER A O   1 
ATOM 2731 C CB  . SER A 1 340  ? 112.998 107.523 93.703  1.00 89.04  ? 340  SER A CB  1 
ATOM 2732 O OG  . SER A 1 340  ? 113.086 106.302 92.984  1.00 84.30  ? 340  SER A OG  1 
ATOM 2733 N N   . SER A 1 341  ? 114.578 105.263 95.553  1.00 98.41  ? 341  SER A N   1 
ATOM 2734 C CA  . SER A 1 341  ? 115.755 104.495 95.920  1.00 101.61 ? 341  SER A CA  1 
ATOM 2735 C C   . SER A 1 341  ? 115.692 103.089 95.331  1.00 85.55  ? 341  SER A C   1 
ATOM 2736 O O   . SER A 1 341  ? 114.618 102.505 95.161  1.00 80.60  ? 341  SER A O   1 
ATOM 2737 C CB  . SER A 1 341  ? 115.924 104.454 97.417  1.00 117.73 ? 341  SER A CB  1 
ATOM 2738 O OG  . SER A 1 341  ? 114.827 103.792 98.036  1.00 126.92 ? 341  SER A OG  1 
ATOM 2739 N N   . PRO A 1 342  ? 116.862 102.467 95.083  1.00 77.21  ? 342  PRO A N   1 
ATOM 2740 C CA  . PRO A 1 342  ? 116.894 101.131 94.507  1.00 74.31  ? 342  PRO A CA  1 
ATOM 2741 C C   . PRO A 1 342  ? 115.959 100.287 95.358  1.00 66.95  ? 342  PRO A C   1 
ATOM 2742 O O   . PRO A 1 342  ? 115.089 99.600  94.838  1.00 62.65  ? 342  PRO A O   1 
ATOM 2743 C CB  . PRO A 1 342  ? 118.356 100.676 94.628  1.00 82.62  ? 342  PRO A CB  1 
ATOM 2744 C CG  . PRO A 1 342  ? 119.146 101.962 94.814  1.00 85.13  ? 342  PRO A CG  1 
ATOM 2745 C CD  . PRO A 1 342  ? 118.197 102.948 95.467  1.00 81.33  ? 342  PRO A CD  1 
ATOM 2746 N N   . GLU A 1 343  ? 116.132 100.408 96.677  1.00 71.14  ? 343  GLU A N   1 
ATOM 2747 C CA  . GLU A 1 343  ? 115.383 99.631  97.647  1.00 76.85  ? 343  GLU A CA  1 
ATOM 2748 C C   . GLU A 1 343  ? 113.907 99.608  97.278  1.00 59.71  ? 343  GLU A C   1 
ATOM 2749 O O   . GLU A 1 343  ? 113.231 98.618  97.515  1.00 63.76  ? 343  GLU A O   1 
ATOM 2750 C CB  . GLU A 1 343  ? 115.530 100.201 99.063  1.00 98.55  ? 343  GLU A CB  1 
ATOM 2751 C CG  . GLU A 1 343  ? 116.961 100.289 99.594  1.00 118.14 ? 343  GLU A CG  1 
ATOM 2752 C CD  . GLU A 1 343  ? 117.708 98.971  99.728  1.00 136.04 ? 343  GLU A CD  1 
ATOM 2753 O OE1 . GLU A 1 343  ? 118.047 98.585  100.872 1.00 148.21 ? 343  GLU A OE1 1 
ATOM 2754 O OE2 . GLU A 1 343  ? 117.950 98.330  98.684  1.00 142.35 ? 343  GLU A OE2 1 
ATOM 2755 N N   . ALA A 1 344  ? 113.390 100.711 96.757  1.00 56.82  ? 344  ALA A N   1 
ATOM 2756 C CA  . ALA A 1 344  ? 111.971 100.783 96.471  1.00 66.92  ? 344  ALA A CA  1 
ATOM 2757 C C   . ALA A 1 344  ? 111.553 99.603  95.604  1.00 66.49  ? 344  ALA A C   1 
ATOM 2758 O O   . ALA A 1 344  ? 110.471 99.054  95.811  1.00 66.63  ? 344  ALA A O   1 
ATOM 2759 C CB  . ALA A 1 344  ? 111.649 102.092 95.803  1.00 80.17  ? 344  ALA A CB  1 
ATOM 2760 N N   . TYR A 1 345  ? 112.402 99.248  94.626  1.00 70.09  ? 345  TYR A N   1 
ATOM 2761 C CA  . TYR A 1 345  ? 112.154 98.101  93.760  1.00 75.24  ? 345  TYR A CA  1 
ATOM 2762 C C   . TYR A 1 345  ? 112.220 96.815  94.580  1.00 68.88  ? 345  TYR A C   1 
ATOM 2763 O O   . TYR A 1 345  ? 111.268 96.038  94.611  1.00 60.52  ? 345  TYR A O   1 
ATOM 2764 C CB  . TYR A 1 345  ? 113.155 98.035  92.595  1.00 80.01  ? 345  TYR A CB  1 
ATOM 2765 C CG  . TYR A 1 345  ? 113.082 99.175  91.608  1.00 74.00  ? 345  TYR A CG  1 
ATOM 2766 C CD1 . TYR A 1 345  ? 111.963 99.371  90.817  1.00 67.23  ? 345  TYR A CD1 1 
ATOM 2767 C CD2 . TYR A 1 345  ? 114.139 100.063 91.472  1.00 71.85  ? 345  TYR A CD2 1 
ATOM 2768 C CE1 . TYR A 1 345  ? 111.883 100.442 89.946  1.00 74.55  ? 345  TYR A CE1 1 
ATOM 2769 C CE2 . TYR A 1 345  ? 114.077 101.135 90.603  1.00 72.06  ? 345  TYR A CE2 1 
ATOM 2770 C CZ  . TYR A 1 345  ? 112.948 101.321 89.829  1.00 81.58  ? 345  TYR A CZ  1 
ATOM 2771 O OH  . TYR A 1 345  ? 112.886 102.391 88.960  1.00 85.46  ? 345  TYR A OH  1 
ATOM 2772 N N   . ILE A 1 346  ? 113.350 96.606  95.266  1.00 63.11  ? 346  ILE A N   1 
ATOM 2773 C CA  . ILE A 1 346  ? 113.565 95.354  95.970  1.00 58.68  ? 346  ILE A CA  1 
ATOM 2774 C C   . ILE A 1 346  ? 112.297 95.016  96.742  1.00 53.09  ? 346  ILE A C   1 
ATOM 2775 O O   . ILE A 1 346  ? 111.774 93.919  96.600  1.00 56.82  ? 346  ILE A O   1 
ATOM 2776 C CB  . ILE A 1 346  ? 114.814 95.376  96.872  1.00 58.95  ? 346  ILE A CB  1 
ATOM 2777 C CG1 . ILE A 1 346  ? 116.078 95.716  96.072  1.00 65.80  ? 346  ILE A CG1 1 
ATOM 2778 C CG2 . ILE A 1 346  ? 114.946 94.040  97.586  1.00 61.80  ? 346  ILE A CG2 1 
ATOM 2779 C CD1 . ILE A 1 346  ? 117.362 95.714  96.872  1.00 69.68  ? 346  ILE A CD1 1 
ATOM 2780 N N   . ARG A 1 347  ? 111.786 95.977  97.510  1.00 55.02  ? 347  ARG A N   1 
ATOM 2781 C CA  . ARG A 1 347  ? 110.632 95.739  98.360  1.00 59.93  ? 347  ARG A CA  1 
ATOM 2782 C C   . ARG A 1 347  ? 109.466 95.272  97.497  1.00 53.69  ? 347  ARG A C   1 
ATOM 2783 O O   . ARG A 1 347  ? 108.789 94.313  97.865  1.00 54.29  ? 347  ARG A O   1 
ATOM 2784 C CB  . ARG A 1 347  ? 110.295 96.995  99.179  1.00 70.03  ? 347  ARG A CB  1 
ATOM 2785 C CG  . ARG A 1 347  ? 109.100 96.871  100.119 1.00 72.22  ? 347  ARG A CG  1 
ATOM 2786 C CD  . ARG A 1 347  ? 109.346 95.933  101.285 1.00 70.05  ? 347  ARG A CD  1 
ATOM 2787 N NE  . ARG A 1 347  ? 108.222 95.900  102.214 1.00 64.93  ? 347  ARG A NE  1 
ATOM 2788 C CZ  . ARG A 1 347  ? 107.462 94.845  102.471 1.00 73.81  ? 347  ARG A CZ  1 
ATOM 2789 N NH1 . ARG A 1 347  ? 107.680 93.687  101.871 1.00 88.69  ? 347  ARG A NH1 1 
ATOM 2790 N NH2 . ARG A 1 347  ? 106.483 94.943  103.350 1.00 70.57  ? 347  ARG A NH2 1 
ATOM 2791 N N   . CYS A 1 348  ? 109.240 95.938  96.358  1.00 55.73  ? 348  CYS A N   1 
ATOM 2792 C CA  . CYS A 1 348  ? 108.071 95.627  95.558  1.00 68.48  ? 348  CYS A CA  1 
ATOM 2793 C C   . CYS A 1 348  ? 108.160 94.193  95.028  1.00 76.79  ? 348  CYS A C   1 
ATOM 2794 O O   . CYS A 1 348  ? 107.177 93.460  95.109  1.00 78.30  ? 348  CYS A O   1 
ATOM 2795 C CB  . CYS A 1 348  ? 107.863 96.604  94.409  1.00 78.66  ? 348  CYS A CB  1 
ATOM 2796 S SG  . CYS A 1 348  ? 106.304 96.321  93.527  1.00 119.80 ? 348  CYS A SG  1 
ATOM 2797 N N   . LEU A 1 349  ? 109.320 93.776  94.494  1.00 72.69  ? 349  LEU A N   1 
ATOM 2798 C CA  . LEU A 1 349  ? 109.376 92.478  93.829  1.00 64.25  ? 349  LEU A CA  1 
ATOM 2799 C C   . LEU A 1 349  ? 109.178 91.365  94.859  1.00 62.75  ? 349  LEU A C   1 
ATOM 2800 O O   . LEU A 1 349  ? 108.457 90.412  94.585  1.00 65.34  ? 349  LEU A O   1 
ATOM 2801 C CB  . LEU A 1 349  ? 110.677 92.300  93.037  1.00 63.42  ? 349  LEU A CB  1 
ATOM 2802 C CG  . LEU A 1 349  ? 110.768 93.072  91.721  1.00 71.19  ? 349  LEU A CG  1 
ATOM 2803 C CD1 . LEU A 1 349  ? 111.225 94.499  91.980  1.00 80.73  ? 349  LEU A CD1 1 
ATOM 2804 C CD2 . LEU A 1 349  ? 111.720 92.387  90.747  1.00 73.25  ? 349  LEU A CD2 1 
ATOM 2805 N N   . ARG A 1 350  ? 109.776 91.490  96.054  1.00 54.01  ? 350  ARG A N   1 
ATOM 2806 C CA  . ARG A 1 350  ? 109.616 90.459  97.064  1.00 46.21  ? 350  ARG A CA  1 
ATOM 2807 C C   . ARG A 1 350  ? 108.161 90.393  97.520  1.00 47.35  ? 350  ARG A C   1 
ATOM 2808 O O   . ARG A 1 350  ? 107.626 89.301  97.681  1.00 52.00  ? 350  ARG A O   1 
ATOM 2809 C CB  . ARG A 1 350  ? 110.570 90.667  98.237  1.00 43.38  ? 350  ARG A CB  1 
ATOM 2810 C CG  . ARG A 1 350  ? 112.036 90.512  97.868  1.00 43.78  ? 350  ARG A CG  1 
ATOM 2811 C CD  . ARG A 1 350  ? 112.861 90.698  99.120  1.00 48.42  ? 350  ARG A CD  1 
ATOM 2812 N NE  . ARG A 1 350  ? 114.282 90.528  98.884  1.00 55.18  ? 350  ARG A NE  1 
ATOM 2813 C CZ  . ARG A 1 350  ? 115.028 89.600  99.468  1.00 68.10  ? 350  ARG A CZ  1 
ATOM 2814 N NH1 . ARG A 1 350  ? 114.470 88.719  100.282 1.00 71.27  ? 350  ARG A NH1 1 
ATOM 2815 N NH2 . ARG A 1 350  ? 116.330 89.559  99.236  1.00 75.73  ? 350  ARG A NH2 1 
ATOM 2816 N N   . MET A 1 351  ? 107.505 91.539  97.714  1.00 53.04  ? 351  MET A N   1 
ATOM 2817 C CA  . MET A 1 351  ? 106.082 91.512  98.019  1.00 61.55  ? 351  MET A CA  1 
ATOM 2818 C C   . MET A 1 351  ? 105.413 90.595  97.007  1.00 53.29  ? 351  MET A C   1 
ATOM 2819 O O   . MET A 1 351  ? 104.407 89.964  97.301  1.00 49.76  ? 351  MET A O   1 
ATOM 2820 C CB  . MET A 1 351  ? 105.425 92.896  97.943  1.00 74.44  ? 351  MET A CB  1 
ATOM 2821 C CG  . MET A 1 351  ? 105.449 93.673  99.246  1.00 87.62  ? 351  MET A CG  1 
ATOM 2822 S SD  . MET A 1 351  ? 104.613 95.265  99.036  1.00 117.03 ? 351  MET A SD  1 
ATOM 2823 C CE  . MET A 1 351  ? 105.455 96.263  100.260 1.00 123.67 ? 351  MET A CE  1 
ATOM 2824 N N   . GLY A 1 352  ? 105.988 90.553  95.806  1.00 59.89  ? 352  GLY A N   1 
ATOM 2825 C CA  . GLY A 1 352  ? 105.540 89.644  94.772  1.00 74.60  ? 352  GLY A CA  1 
ATOM 2826 C C   . GLY A 1 352  ? 104.840 90.376  93.628  1.00 86.76  ? 352  GLY A C   1 
ATOM 2827 O O   . GLY A 1 352  ? 104.095 89.750  92.875  1.00 83.22  ? 352  GLY A O   1 
ATOM 2828 N N   . CYS A 1 353  ? 105.086 91.689  93.484  1.00 86.27  ? 353  CYS A N   1 
ATOM 2829 C CA  . CYS A 1 353  ? 104.642 92.388  92.292  1.00 84.81  ? 353  CYS A CA  1 
ATOM 2830 C C   . CYS A 1 353  ? 105.495 91.905  91.130  1.00 80.62  ? 353  CYS A C   1 
ATOM 2831 O O   . CYS A 1 353  ? 106.708 91.767  91.284  1.00 77.66  ? 353  CYS A O   1 
ATOM 2832 C CB  . CYS A 1 353  ? 104.768 93.901  92.413  1.00 101.13 ? 353  CYS A CB  1 
ATOM 2833 S SG  . CYS A 1 353  ? 106.474 94.496  92.568  1.00 122.36 ? 353  CYS A SG  1 
ATOM 2834 N N   . ARG A 1 354  ? 104.839 91.637  89.990  1.00 71.75  ? 354  ARG A N   1 
ATOM 2835 C CA  . ARG A 1 354  ? 105.502 91.121  88.806  1.00 61.68  ? 354  ARG A CA  1 
ATOM 2836 C C   . ARG A 1 354  ? 105.201 92.046  87.636  1.00 70.22  ? 354  ARG A C   1 
ATOM 2837 O O   . ARG A 1 354  ? 104.468 91.645  86.739  1.00 77.15  ? 354  ARG A O   1 
ATOM 2838 C CB  . ARG A 1 354  ? 104.974 89.728  88.473  1.00 52.87  ? 354  ARG A CB  1 
ATOM 2839 C CG  . ARG A 1 354  ? 105.087 88.711  89.593  1.00 53.81  ? 354  ARG A CG  1 
ATOM 2840 C CD  . ARG A 1 354  ? 106.475 88.160  89.885  1.00 54.34  ? 354  ARG A CD  1 
ATOM 2841 N NE  . ARG A 1 354  ? 107.412 89.069  90.517  1.00 59.02  ? 354  ARG A NE  1 
ATOM 2842 C CZ  . ARG A 1 354  ? 108.637 88.729  90.909  1.00 60.86  ? 354  ARG A CZ  1 
ATOM 2843 N NH1 . ARG A 1 354  ? 109.042 87.482  90.786  1.00 55.63  ? 354  ARG A NH1 1 
ATOM 2844 N NH2 . ARG A 1 354  ? 109.454 89.632  91.430  1.00 71.02  ? 354  ARG A NH2 1 
ATOM 2845 N N   . CYS A 1 355  ? 105.735 93.278  87.675  1.00 64.41  ? 355  CYS A N   1 
ATOM 2846 C CA  . CYS A 1 355  ? 105.500 94.266  86.634  1.00 54.06  ? 355  CYS A CA  1 
ATOM 2847 C C   . CYS A 1 355  ? 106.072 95.612  87.045  1.00 41.70  ? 355  CYS A C   1 
ATOM 2848 O O   . CYS A 1 355  ? 105.384 96.617  86.938  1.00 45.60  ? 355  CYS A O   1 
ATOM 2849 C CB  . CYS A 1 355  ? 104.010 94.421  86.336  1.00 62.23  ? 355  CYS A CB  1 
ATOM 2850 S SG  . CYS A 1 355  ? 103.624 95.651  85.058  1.00 90.30  ? 355  CYS A SG  1 
ATOM 2851 N N   . ILE A 1 356  ? 107.319 95.646  87.498  1.00 40.42  ? 356  ILE A N   1 
ATOM 2852 C CA  . ILE A 1 356  ? 107.875 96.908  87.952  1.00 50.34  ? 356  ILE A CA  1 
ATOM 2853 C C   . ILE A 1 356  ? 107.933 97.870  86.767  1.00 61.18  ? 356  ILE A C   1 
ATOM 2854 O O   . ILE A 1 356  ? 108.143 97.429  85.645  1.00 74.80  ? 356  ILE A O   1 
ATOM 2855 C CB  . ILE A 1 356  ? 109.261 96.709  88.592  1.00 59.63  ? 356  ILE A CB  1 
ATOM 2856 C CG1 . ILE A 1 356  ? 110.279 96.187  87.569  1.00 67.43  ? 356  ILE A CG1 1 
ATOM 2857 C CG2 . ILE A 1 356  ? 109.146 95.826  89.831  1.00 64.88  ? 356  ILE A CG2 1 
ATOM 2858 C CD1 . ILE A 1 356  ? 111.653 95.887  88.141  1.00 73.65  ? 356  ILE A CD1 1 
ATOM 2859 N N   . GLU A 1 357  ? 107.748 99.178  87.018  1.00 63.45  ? 357  GLU A N   1 
ATOM 2860 C CA  . GLU A 1 357  ? 107.922 100.222 86.016  1.00 59.61  ? 357  GLU A CA  1 
ATOM 2861 C C   . GLU A 1 357  ? 109.262 100.895 86.282  1.00 50.54  ? 357  GLU A C   1 
ATOM 2862 O O   . GLU A 1 357  ? 109.763 100.839 87.395  1.00 51.03  ? 357  GLU A O   1 
ATOM 2863 C CB  . GLU A 1 357  ? 106.755 101.202 86.102  1.00 70.87  ? 357  GLU A CB  1 
ATOM 2864 C CG  . GLU A 1 357  ? 106.785 102.323 85.070  1.00 97.37  ? 357  GLU A CG  1 
ATOM 2865 C CD  . GLU A 1 357  ? 105.592 103.278 85.124  1.00 121.20 ? 357  GLU A CD  1 
ATOM 2866 O OE1 . GLU A 1 357  ? 105.794 104.486 85.387  1.00 123.89 ? 357  GLU A OE1 1 
ATOM 2867 O OE2 . GLU A 1 357  ? 104.454 102.823 84.899  1.00 121.31 ? 357  GLU A OE2 1 
ATOM 2868 N N   . LEU A 1 358  ? 109.857 101.509 85.264  1.00 53.16  ? 358  LEU A N   1 
ATOM 2869 C CA  . LEU A 1 358  ? 111.219 102.000 85.394  1.00 60.56  ? 358  LEU A CA  1 
ATOM 2870 C C   . LEU A 1 358  ? 111.429 103.227 84.509  1.00 72.02  ? 358  LEU A C   1 
ATOM 2871 O O   . LEU A 1 358  ? 112.256 103.160 83.607  1.00 81.01  ? 358  LEU A O   1 
ATOM 2872 C CB  . LEU A 1 358  ? 112.158 100.869 84.966  1.00 58.32  ? 358  LEU A CB  1 
ATOM 2873 C CG  . LEU A 1 358  ? 113.485 100.782 85.717  1.00 66.93  ? 358  LEU A CG  1 
ATOM 2874 C CD1 . LEU A 1 358  ? 113.520 99.539  86.594  1.00 80.44  ? 358  LEU A CD1 1 
ATOM 2875 C CD2 . LEU A 1 358  ? 114.671 100.799 84.767  1.00 67.14  ? 358  LEU A CD2 1 
ATOM 2876 N N   . ASP A 1 359  ? 110.694 104.323 84.769  1.00 70.12  ? 359  ASP A N   1 
ATOM 2877 C CA  . ASP A 1 359  ? 110.794 105.542 83.971  1.00 64.14  ? 359  ASP A CA  1 
ATOM 2878 C C   . ASP A 1 359  ? 112.229 106.049 84.013  1.00 57.65  ? 359  ASP A C   1 
ATOM 2879 O O   . ASP A 1 359  ? 112.817 106.152 85.086  1.00 54.76  ? 359  ASP A O   1 
ATOM 2880 C CB  . ASP A 1 359  ? 109.881 106.672 84.461  1.00 71.21  ? 359  ASP A CB  1 
ATOM 2881 C CG  . ASP A 1 359  ? 108.388 106.358 84.485  1.00 77.73  ? 359  ASP A CG  1 
ATOM 2882 O OD1 . ASP A 1 359  ? 108.004 105.284 83.984  1.00 88.88  ? 359  ASP A OD1 1 
ATOM 2883 O OD2 . ASP A 1 359  ? 107.615 107.181 85.030  1.00 64.66  ? 359  ASP A OD2 1 
ATOM 2884 N N   . CYS A 1 360  ? 112.777 106.368 82.838  1.00 59.56  ? 360  CYS A N   1 
ATOM 2885 C CA  . CYS A 1 360  ? 114.190 106.684 82.699  1.00 67.22  ? 360  CYS A CA  1 
ATOM 2886 C C   . CYS A 1 360  ? 114.349 108.008 81.966  1.00 71.30  ? 360  CYS A C   1 
ATOM 2887 O O   . CYS A 1 360  ? 113.649 108.254 80.991  1.00 84.39  ? 360  CYS A O   1 
ATOM 2888 C CB  . CYS A 1 360  ? 114.903 105.573 81.945  1.00 72.35  ? 360  CYS A CB  1 
ATOM 2889 S SG  . CYS A 1 360  ? 113.825 104.799 80.709  1.00 84.76  ? 360  CYS A SG  1 
ATOM 2890 N N   . TRP A 1 361  ? 115.266 108.846 82.458  1.00 69.85  ? 361  TRP A N   1 
ATOM 2891 C CA  . TRP A 1 361  ? 115.531 110.150 81.876  1.00 69.94  ? 361  TRP A CA  1 
ATOM 2892 C C   . TRP A 1 361  ? 117.029 110.294 81.650  1.00 75.26  ? 361  TRP A C   1 
ATOM 2893 O O   . TRP A 1 361  ? 117.809 109.581 82.262  1.00 76.86  ? 361  TRP A O   1 
ATOM 2894 C CB  . TRP A 1 361  ? 114.951 111.258 82.763  1.00 65.87  ? 361  TRP A CB  1 
ATOM 2895 C CG  . TRP A 1 361  ? 113.463 111.345 82.647  1.00 68.15  ? 361  TRP A CG  1 
ATOM 2896 C CD1 . TRP A 1 361  ? 112.541 110.486 83.162  1.00 72.60  ? 361  TRP A CD1 1 
ATOM 2897 C CD2 . TRP A 1 361  ? 112.719 112.319 81.903  1.00 81.70  ? 361  TRP A CD2 1 
ATOM 2898 N NE1 . TRP A 1 361  ? 111.276 110.866 82.808  1.00 78.91  ? 361  TRP A NE1 1 
ATOM 2899 C CE2 . TRP A 1 361  ? 111.355 111.988 82.035  1.00 84.77  ? 361  TRP A CE2 1 
ATOM 2900 C CE3 . TRP A 1 361  ? 113.073 113.441 81.146  1.00 106.38 ? 361  TRP A CE3 1 
ATOM 2901 C CZ2 . TRP A 1 361  ? 110.345 112.745 81.444  1.00 105.57 ? 361  TRP A CZ2 1 
ATOM 2902 C CZ3 . TRP A 1 361  ? 112.074 114.191 80.561  1.00 122.69 ? 361  TRP A CZ3 1 
ATOM 2903 C CH2 . TRP A 1 361  ? 110.729 113.844 80.709  1.00 122.06 ? 361  TRP A CH2 1 
ATOM 2904 N N   . ASP A 1 362  ? 117.414 111.203 80.752  1.00 87.93  ? 362  ASP A N   1 
ATOM 2905 C CA  . ASP A 1 362  ? 118.806 111.357 80.361  1.00 99.05  ? 362  ASP A CA  1 
ATOM 2906 C C   . ASP A 1 362  ? 119.628 111.696 81.598  1.00 87.11  ? 362  ASP A C   1 
ATOM 2907 O O   . ASP A 1 362  ? 119.174 112.436 82.468  1.00 89.73  ? 362  ASP A O   1 
ATOM 2908 C CB  . ASP A 1 362  ? 118.994 112.459 79.315  1.00 134.26 ? 362  ASP A CB  1 
ATOM 2909 C CG  . ASP A 1 362  ? 117.937 112.467 78.223  1.00 167.88 ? 362  ASP A CG  1 
ATOM 2910 O OD1 . ASP A 1 362  ? 116.745 112.597 78.564  1.00 182.30 ? 362  ASP A OD1 1 
ATOM 2911 O OD2 . ASP A 1 362  ? 118.314 112.349 77.045  1.00 183.80 ? 362  ASP A OD2 1 
ATOM 2912 N N   . GLY A 1 363  ? 120.855 111.174 81.640  1.00 85.85  ? 363  GLY A N   1 
ATOM 2913 C CA  . GLY A 1 363  ? 121.696 111.268 82.819  1.00 88.32  ? 363  GLY A CA  1 
ATOM 2914 C C   . GLY A 1 363  ? 122.973 112.055 82.547  1.00 93.85  ? 363  GLY A C   1 
ATOM 2915 O O   . GLY A 1 363  ? 123.376 112.223 81.398  1.00 104.65 ? 363  GLY A O   1 
ATOM 2916 N N   . PRO A 1 364  ? 123.651 112.538 83.609  1.00 110.00 ? 364  PRO A N   1 
ATOM 2917 C CA  . PRO A 1 364  ? 124.805 113.425 83.472  1.00 125.77 ? 364  PRO A CA  1 
ATOM 2918 C C   . PRO A 1 364  ? 125.903 112.943 82.528  1.00 138.02 ? 364  PRO A C   1 
ATOM 2919 O O   . PRO A 1 364  ? 126.401 113.724 81.718  1.00 154.51 ? 364  PRO A O   1 
ATOM 2920 C CB  . PRO A 1 364  ? 125.363 113.494 84.901  1.00 131.95 ? 364  PRO A CB  1 
ATOM 2921 C CG  . PRO A 1 364  ? 124.150 113.281 85.770  1.00 134.20 ? 364  PRO A CG  1 
ATOM 2922 C CD  . PRO A 1 364  ? 123.325 112.261 85.015  1.00 125.44 ? 364  PRO A CD  1 
ATOM 2923 N N   . ASP A 1 365  ? 126.293 111.669 82.645  1.00 139.47 ? 365  ASP A N   1 
ATOM 2924 C CA  . ASP A 1 365  ? 127.464 111.189 81.931  1.00 149.56 ? 365  ASP A CA  1 
ATOM 2925 C C   . ASP A 1 365  ? 127.174 109.834 81.295  1.00 138.26 ? 365  ASP A C   1 
ATOM 2926 O O   . ASP A 1 365  ? 127.704 108.809 81.724  1.00 136.70 ? 365  ASP A O   1 
ATOM 2927 C CB  . ASP A 1 365  ? 128.675 111.164 82.865  1.00 168.57 ? 365  ASP A CB  1 
ATOM 2928 C CG  . ASP A 1 365  ? 128.927 112.510 83.522  1.00 181.45 ? 365  ASP A CG  1 
ATOM 2929 O OD1 . ASP A 1 365  ? 129.187 113.479 82.782  1.00 188.21 ? 365  ASP A OD1 1 
ATOM 2930 O OD2 . ASP A 1 365  ? 128.819 112.585 84.761  1.00 189.29 ? 365  ASP A OD2 1 
ATOM 2931 N N   . GLY A 1 366  ? 126.332 109.852 80.257  1.00 125.73 ? 366  GLY A N   1 
ATOM 2932 C CA  . GLY A 1 366  ? 126.104 108.681 79.429  1.00 120.75 ? 366  GLY A CA  1 
ATOM 2933 C C   . GLY A 1 366  ? 125.088 107.728 80.052  1.00 107.34 ? 366  GLY A C   1 
ATOM 2934 O O   . GLY A 1 366  ? 124.041 107.455 79.470  1.00 109.67 ? 366  GLY A O   1 
ATOM 2935 N N   . LYS A 1 367  ? 125.433 107.214 81.233  1.00 89.86  ? 367  LYS A N   1 
ATOM 2936 C CA  . LYS A 1 367  ? 124.578 106.299 81.965  1.00 84.74  ? 367  LYS A CA  1 
ATOM 2937 C C   . LYS A 1 367  ? 123.227 106.966 82.190  1.00 66.70  ? 367  LYS A C   1 
ATOM 2938 O O   . LYS A 1 367  ? 123.177 108.101 82.647  1.00 63.63  ? 367  LYS A O   1 
ATOM 2939 C CB  . LYS A 1 367  ? 125.176 105.940 83.327  1.00 107.51 ? 367  LYS A CB  1 
ATOM 2940 C CG  . LYS A 1 367  ? 126.601 106.427 83.575  1.00 126.57 ? 367  LYS A CG  1 
ATOM 2941 C CD  . LYS A 1 367  ? 127.545 105.353 84.023  1.00 134.41 ? 367  LYS A CD  1 
ATOM 2942 C CE  . LYS A 1 367  ? 127.868 104.392 82.900  1.00 138.90 ? 367  LYS A CE  1 
ATOM 2943 N NZ  . LYS A 1 367  ? 128.751 103.293 83.361  1.00 144.02 ? 367  LYS A NZ  1 
ATOM 2944 N N   . PRO A 1 368  ? 122.096 106.283 81.917  1.00 62.81  ? 368  PRO A N   1 
ATOM 2945 C CA  . PRO A 1 368  ? 120.783 106.835 82.218  1.00 60.81  ? 368  PRO A CA  1 
ATOM 2946 C C   . PRO A 1 368  ? 120.630 106.965 83.729  1.00 59.66  ? 368  PRO A C   1 
ATOM 2947 O O   . PRO A 1 368  ? 121.352 106.313 84.481  1.00 66.27  ? 368  PRO A O   1 
ATOM 2948 C CB  . PRO A 1 368  ? 119.768 105.820 81.667  1.00 65.49  ? 368  PRO A CB  1 
ATOM 2949 C CG  . PRO A 1 368  ? 120.585 104.877 80.804  1.00 70.78  ? 368  PRO A CG  1 
ATOM 2950 C CD  . PRO A 1 368  ? 122.000 104.934 81.348  1.00 71.38  ? 368  PRO A CD  1 
ATOM 2951 N N   . VAL A 1 369  ? 119.692 107.823 84.144  1.00 53.05  ? 369  VAL A N   1 
ATOM 2952 C CA  . VAL A 1 369  ? 119.309 107.991 85.535  1.00 48.32  ? 369  VAL A CA  1 
ATOM 2953 C C   . VAL A 1 369  ? 117.793 107.911 85.608  1.00 49.38  ? 369  VAL A C   1 
ATOM 2954 O O   . VAL A 1 369  ? 117.124 108.214 84.626  1.00 58.17  ? 369  VAL A O   1 
ATOM 2955 C CB  . VAL A 1 369  ? 119.815 109.329 86.098  1.00 48.87  ? 369  VAL A CB  1 
ATOM 2956 C CG1 . VAL A 1 369  ? 121.336 109.411 86.059  1.00 52.89  ? 369  VAL A CG1 1 
ATOM 2957 C CG2 . VAL A 1 369  ? 119.195 110.515 85.371  1.00 51.28  ? 369  VAL A CG2 1 
ATOM 2958 N N   . ILE A 1 370  ? 117.258 107.507 86.766  1.00 48.66  ? 370  ILE A N   1 
ATOM 2959 C CA  . ILE A 1 370  ? 115.822 107.402 86.953  1.00 50.48  ? 370  ILE A CA  1 
ATOM 2960 C C   . ILE A 1 370  ? 115.355 108.451 87.960  1.00 68.14  ? 370  ILE A C   1 
ATOM 2961 O O   . ILE A 1 370  ? 115.894 108.557 89.060  1.00 84.13  ? 370  ILE A O   1 
ATOM 2962 C CB  . ILE A 1 370  ? 115.442 105.978 87.375  1.00 49.61  ? 370  ILE A CB  1 
ATOM 2963 C CG1 . ILE A 1 370  ? 115.677 105.005 86.218  1.00 62.08  ? 370  ILE A CG1 1 
ATOM 2964 C CG2 . ILE A 1 370  ? 114.023 105.947 87.900  1.00 51.26  ? 370  ILE A CG2 1 
ATOM 2965 C CD1 . ILE A 1 370  ? 114.671 103.867 86.074  1.00 69.12  ? 370  ILE A CD1 1 
ATOM 2966 N N   . TYR A 1 371  ? 114.349 109.240 87.557  1.00 72.90  ? 371  TYR A N   1 
ATOM 2967 C CA  . TYR A 1 371  ? 113.720 110.250 88.403  1.00 67.14  ? 371  TYR A CA  1 
ATOM 2968 C C   . TYR A 1 371  ? 112.307 110.447 87.859  1.00 56.40  ? 371  TYR A C   1 
ATOM 2969 O O   . TYR A 1 371  ? 112.085 110.234 86.677  1.00 57.90  ? 371  TYR A O   1 
ATOM 2970 C CB  . TYR A 1 371  ? 114.610 111.504 88.495  1.00 69.46  ? 371  TYR A CB  1 
ATOM 2971 C CG  . TYR A 1 371  ? 114.411 112.614 87.490  1.00 83.45  ? 371  TYR A CG  1 
ATOM 2972 C CD1 . TYR A 1 371  ? 114.278 112.381 86.127  1.00 104.93 ? 371  TYR A CD1 1 
ATOM 2973 C CD2 . TYR A 1 371  ? 114.441 113.934 87.909  1.00 102.60 ? 371  TYR A CD2 1 
ATOM 2974 C CE1 . TYR A 1 371  ? 114.113 113.423 85.223  1.00 126.80 ? 371  TYR A CE1 1 
ATOM 2975 C CE2 . TYR A 1 371  ? 114.288 114.987 87.021  1.00 128.57 ? 371  TYR A CE2 1 
ATOM 2976 C CZ  . TYR A 1 371  ? 114.119 114.734 85.670  1.00 140.83 ? 371  TYR A CZ  1 
ATOM 2977 O OH  . TYR A 1 371  ? 113.957 115.776 84.781  1.00 159.19 ? 371  TYR A OH  1 
ATOM 2978 N N   . HIS A 1 372  ? 111.325 110.760 88.705  1.00 54.91  ? 372  HIS A N   1 
ATOM 2979 C CA  . HIS A 1 372  ? 110.050 111.173 88.145  1.00 56.35  ? 372  HIS A CA  1 
ATOM 2980 C C   . HIS A 1 372  ? 110.375 112.416 87.341  1.00 68.51  ? 372  HIS A C   1 
ATOM 2981 O O   . HIS A 1 372  ? 111.391 113.046 87.620  1.00 63.54  ? 372  HIS A O   1 
ATOM 2982 C CB  . HIS A 1 372  ? 108.967 111.422 89.198  1.00 52.34  ? 372  HIS A CB  1 
ATOM 2983 C CG  . HIS A 1 372  ? 107.611 111.537 88.596  1.00 48.02  ? 372  HIS A CG  1 
ATOM 2984 N ND1 . HIS A 1 372  ? 106.519 112.053 89.251  1.00 53.51  ? 372  HIS A ND1 1 
ATOM 2985 C CD2 . HIS A 1 372  ? 107.186 111.196 87.379  1.00 48.08  ? 372  HIS A CD2 1 
ATOM 2986 C CE1 . HIS A 1 372  ? 105.468 112.002 88.448  1.00 58.10  ? 372  HIS A CE1 1 
ATOM 2987 N NE2 . HIS A 1 372  ? 105.853 111.484 87.305  1.00 54.89  ? 372  HIS A NE2 1 
ATOM 2988 N N   . GLY A 1 373  ? 109.522 112.750 86.360  1.00 85.66  ? 373  GLY A N   1 
ATOM 2989 C CA  . GLY A 1 373  ? 109.872 113.686 85.301  1.00 97.14  ? 373  GLY A CA  1 
ATOM 2990 C C   . GLY A 1 373  ? 109.463 115.126 85.605  1.00 90.62  ? 373  GLY A C   1 
ATOM 2991 O O   . GLY A 1 373  ? 108.275 115.422 85.744  1.00 81.59  ? 373  GLY A O   1 
ATOM 2992 N N   . TRP A 1 374  ? 110.474 116.007 85.666  1.00 85.15  ? 374  TRP A N   1 
ATOM 2993 C CA  . TRP A 1 374  ? 110.281 117.421 85.916  1.00 90.17  ? 374  TRP A CA  1 
ATOM 2994 C C   . TRP A 1 374  ? 110.045 117.660 87.406  1.00 87.98  ? 374  TRP A C   1 
ATOM 2995 O O   . TRP A 1 374  ? 110.232 118.772 87.898  1.00 104.30 ? 374  TRP A O   1 
ATOM 2996 C CB  . TRP A 1 374  ? 109.153 117.965 85.026  1.00 101.50 ? 374  TRP A CB  1 
ATOM 2997 C CG  . TRP A 1 374  ? 109.367 117.665 83.572  1.00 105.05 ? 374  TRP A CG  1 
ATOM 2998 C CD1 . TRP A 1 374  ? 108.542 116.976 82.728  1.00 101.19 ? 374  TRP A CD1 1 
ATOM 2999 C CD2 . TRP A 1 374  ? 110.515 118.043 82.792  1.00 107.39 ? 374  TRP A CD2 1 
ATOM 3000 N NE1 . TRP A 1 374  ? 109.098 116.900 81.480  1.00 105.29 ? 374  TRP A NE1 1 
ATOM 3001 C CE2 . TRP A 1 374  ? 110.308 117.546 81.489  1.00 112.09 ? 374  TRP A CE2 1 
ATOM 3002 C CE3 . TRP A 1 374  ? 111.692 118.747 83.071  1.00 110.24 ? 374  TRP A CE3 1 
ATOM 3003 C CZ2 . TRP A 1 374  ? 111.237 117.747 80.468  1.00 125.32 ? 374  TRP A CZ2 1 
ATOM 3004 C CZ3 . TRP A 1 374  ? 112.604 118.949 82.062  1.00 117.03 ? 374  TRP A CZ3 1 
ATOM 3005 C CH2 . TRP A 1 374  ? 112.382 118.447 80.780  1.00 125.24 ? 374  TRP A CH2 1 
ATOM 3006 N N   . THR A 1 375  ? 109.642 116.604 88.117  1.00 78.02  ? 375  THR A N   1 
ATOM 3007 C CA  . THR A 1 375  ? 109.499 116.640 89.562  1.00 79.61  ? 375  THR A CA  1 
ATOM 3008 C C   . THR A 1 375  ? 110.889 116.695 90.195  1.00 74.74  ? 375  THR A C   1 
ATOM 3009 O O   . THR A 1 375  ? 111.879 116.390 89.528  1.00 78.29  ? 375  THR A O   1 
ATOM 3010 C CB  . THR A 1 375  ? 108.697 115.417 90.028  1.00 90.12  ? 375  THR A CB  1 
ATOM 3011 O OG1 . THR A 1 375  ? 109.438 114.248 89.678  1.00 99.81  ? 375  THR A OG1 1 
ATOM 3012 C CG2 . THR A 1 375  ? 107.315 115.336 89.416  1.00 89.35  ? 375  THR A CG2 1 
ATOM 3013 N N   . ARG A 1 376  ? 110.949 117.060 91.483  1.00 71.47  ? 376  ARG A N   1 
ATOM 3014 C CA  . ARG A 1 376  ? 112.211 117.261 92.179  1.00 79.35  ? 376  ARG A CA  1 
ATOM 3015 C C   . ARG A 1 376  ? 112.641 116.013 92.953  1.00 82.76  ? 376  ARG A C   1 
ATOM 3016 O O   . ARG A 1 376  ? 113.587 116.073 93.737  1.00 93.16  ? 376  ARG A O   1 
ATOM 3017 C CB  . ARG A 1 376  ? 112.119 118.482 93.098  1.00 89.59  ? 376  ARG A CB  1 
ATOM 3018 C CG  . ARG A 1 376  ? 112.050 119.792 92.328  1.00 110.81 ? 376  ARG A CG  1 
ATOM 3019 C CD  . ARG A 1 376  ? 111.974 121.050 93.177  1.00 136.91 ? 376  ARG A CD  1 
ATOM 3020 N NE  . ARG A 1 376  ? 111.768 122.226 92.336  1.00 154.54 ? 376  ARG A NE  1 
ATOM 3021 C CZ  . ARG A 1 376  ? 112.640 122.694 91.444  1.00 170.32 ? 376  ARG A CZ  1 
ATOM 3022 N NH1 . ARG A 1 376  ? 113.816 122.113 91.285  1.00 172.75 ? 376  ARG A NH1 1 
ATOM 3023 N NH2 . ARG A 1 376  ? 112.344 123.769 90.731  1.00 172.32 ? 376  ARG A NH2 1 
ATOM 3024 N N   . THR A 1 377  ? 112.012 114.862 92.700  1.00 78.62  ? 377  THR A N   1 
ATOM 3025 C CA  . THR A 1 377  ? 112.404 113.616 93.351  1.00 74.72  ? 377  THR A CA  1 
ATOM 3026 C C   . THR A 1 377  ? 113.833 113.228 92.982  1.00 73.02  ? 377  THR A C   1 
ATOM 3027 O O   . THR A 1 377  ? 114.227 113.401 91.835  1.00 87.15  ? 377  THR A O   1 
ATOM 3028 C CB  . THR A 1 377  ? 111.508 112.451 92.930  1.00 68.09  ? 377  THR A CB  1 
ATOM 3029 O OG1 . THR A 1 377  ? 111.750 112.260 91.540  1.00 65.64  ? 377  THR A OG1 1 
ATOM 3030 C CG2 . THR A 1 377  ? 110.045 112.712 93.206  1.00 69.68  ? 377  THR A CG2 1 
ATOM 3031 N N   . THR A 1 378  ? 114.562 112.651 93.943  1.00 68.48  ? 378  THR A N   1 
ATOM 3032 C CA  . THR A 1 378  ? 115.987 112.372 93.837  1.00 81.52  ? 378  THR A CA  1 
ATOM 3033 C C   . THR A 1 378  ? 116.335 111.414 92.691  1.00 93.76  ? 378  THR A C   1 
ATOM 3034 O O   . THR A 1 378  ? 115.454 110.806 92.084  1.00 97.36  ? 378  THR A O   1 
ATOM 3035 C CB  . THR A 1 378  ? 116.478 111.764 95.153  1.00 93.57  ? 378  THR A CB  1 
ATOM 3036 O OG1 . THR A 1 378  ? 115.729 110.565 95.348  1.00 92.98  ? 378  THR A OG1 1 
ATOM 3037 C CG2 . THR A 1 378  ? 116.295 112.686 96.337  1.00 102.95 ? 378  THR A CG2 1 
ATOM 3038 N N   . LYS A 1 379  ? 117.652 111.256 92.445  1.00 93.48  ? 379  LYS A N   1 
ATOM 3039 C CA  . LYS A 1 379  ? 118.202 110.515 91.316  1.00 91.98  ? 379  LYS A CA  1 
ATOM 3040 C C   . LYS A 1 379  ? 118.782 109.172 91.768  1.00 92.57  ? 379  LYS A C   1 
ATOM 3041 O O   . LYS A 1 379  ? 119.564 109.146 92.717  1.00 99.38  ? 379  LYS A O   1 
ATOM 3042 C CB  . LYS A 1 379  ? 119.369 111.303 90.719  1.00 98.37  ? 379  LYS A CB  1 
ATOM 3043 C CG  . LYS A 1 379  ? 119.246 112.822 90.749  1.00 110.93 ? 379  LYS A CG  1 
ATOM 3044 C CD  . LYS A 1 379  ? 118.997 113.456 89.395  1.00 123.81 ? 379  LYS A CD  1 
ATOM 3045 C CE  . LYS A 1 379  ? 117.700 113.025 88.743  1.00 125.50 ? 379  LYS A CE  1 
ATOM 3046 N NZ  . LYS A 1 379  ? 117.498 113.715 87.448  1.00 120.41 ? 379  LYS A NZ  1 
ATOM 3047 N N   . ILE A 1 380  ? 118.435 108.086 91.052  1.00 81.68  ? 380  ILE A N   1 
ATOM 3048 C CA  . ILE A 1 380  ? 118.950 106.741 91.297  1.00 74.01  ? 380  ILE A CA  1 
ATOM 3049 C C   . ILE A 1 380  ? 119.627 106.231 90.029  1.00 83.23  ? 380  ILE A C   1 
ATOM 3050 O O   . ILE A 1 380  ? 118.953 106.031 89.030  1.00 91.81  ? 380  ILE A O   1 
ATOM 3051 C CB  . ILE A 1 380  ? 117.841 105.751 91.708  1.00 69.70  ? 380  ILE A CB  1 
ATOM 3052 C CG1 . ILE A 1 380  ? 116.563 105.941 90.891  1.00 67.08  ? 380  ILE A CG1 1 
ATOM 3053 C CG2 . ILE A 1 380  ? 117.553 105.830 93.197  1.00 82.33  ? 380  ILE A CG2 1 
ATOM 3054 C CD1 . ILE A 1 380  ? 115.562 104.804 91.027  1.00 70.94  ? 380  ILE A CD1 1 
ATOM 3055 N N   . LYS A 1 381  ? 120.935 105.946 90.090  1.00 82.33  ? 381  LYS A N   1 
ATOM 3056 C CA  . LYS A 1 381  ? 121.690 105.493 88.928  1.00 81.21  ? 381  LYS A CA  1 
ATOM 3057 C C   . LYS A 1 381  ? 121.052 104.232 88.336  1.00 86.74  ? 381  LYS A C   1 
ATOM 3058 O O   . LYS A 1 381  ? 120.671 103.330 89.081  1.00 102.19 ? 381  LYS A O   1 
ATOM 3059 C CB  . LYS A 1 381  ? 123.133 105.218 89.347  1.00 86.26  ? 381  LYS A CB  1 
ATOM 3060 C CG  . LYS A 1 381  ? 123.901 106.439 89.830  1.00 104.88 ? 381  LYS A CG  1 
ATOM 3061 C CD  . LYS A 1 381  ? 124.579 107.220 88.721  1.00 128.46 ? 381  LYS A CD  1 
ATOM 3062 C CE  . LYS A 1 381  ? 125.604 106.407 87.957  1.00 145.50 ? 381  LYS A CE  1 
ATOM 3063 N NZ  . LYS A 1 381  ? 126.543 105.696 88.860  1.00 147.95 ? 381  LYS A NZ  1 
ATOM 3064 N N   . PHE A 1 382  ? 120.955 104.163 86.998  1.00 81.88  ? 382  PHE A N   1 
ATOM 3065 C CA  . PHE A 1 382  ? 120.293 103.059 86.309  1.00 77.13  ? 382  PHE A CA  1 
ATOM 3066 C C   . PHE A 1 382  ? 121.004 101.742 86.585  1.00 77.73  ? 382  PHE A C   1 
ATOM 3067 O O   . PHE A 1 382  ? 120.359 100.719 86.782  1.00 80.63  ? 382  PHE A O   1 
ATOM 3068 C CB  . PHE A 1 382  ? 120.302 103.230 84.787  1.00 77.30  ? 382  PHE A CB  1 
ATOM 3069 C CG  . PHE A 1 382  ? 119.545 102.168 84.026  1.00 68.06  ? 382  PHE A CG  1 
ATOM 3070 C CD1 . PHE A 1 382  ? 118.169 102.227 83.910  1.00 71.18  ? 382  PHE A CD1 1 
ATOM 3071 C CD2 . PHE A 1 382  ? 120.202 101.108 83.429  1.00 67.35  ? 382  PHE A CD2 1 
ATOM 3072 C CE1 . PHE A 1 382  ? 117.469 101.254 83.215  1.00 73.73  ? 382  PHE A CE1 1 
ATOM 3073 C CE2 . PHE A 1 382  ? 119.499 100.134 82.736  1.00 71.81  ? 382  PHE A CE2 1 
ATOM 3074 C CZ  . PHE A 1 382  ? 118.132 100.205 82.633  1.00 72.26  ? 382  PHE A CZ  1 
ATOM 3075 N N   . ASP A 1 383  ? 122.337 101.779 86.551  1.00 82.81  ? 383  ASP A N   1 
ATOM 3076 C CA  . ASP A 1 383  ? 123.127 100.580 86.751  1.00 95.79  ? 383  ASP A CA  1 
ATOM 3077 C C   . ASP A 1 383  ? 122.639 99.895  88.024  1.00 93.24  ? 383  ASP A C   1 
ATOM 3078 O O   . ASP A 1 383  ? 122.319 98.709  88.012  1.00 89.59  ? 383  ASP A O   1 
ATOM 3079 C CB  . ASP A 1 383  ? 124.620 100.916 86.771  1.00 111.95 ? 383  ASP A CB  1 
ATOM 3080 C CG  . ASP A 1 383  ? 125.115 101.528 85.470  1.00 127.69 ? 383  ASP A CG  1 
ATOM 3081 O OD1 . ASP A 1 383  ? 124.260 101.930 84.646  1.00 134.90 ? 383  ASP A OD1 1 
ATOM 3082 O OD2 . ASP A 1 383  ? 126.351 101.584 85.277  1.00 131.56 ? 383  ASP A OD2 1 
ATOM 3083 N N   . ASP A 1 384  ? 122.533 100.682 89.100  1.00 92.00  ? 384  ASP A N   1 
ATOM 3084 C CA  . ASP A 1 384  ? 122.164 100.176 90.410  1.00 90.71  ? 384  ASP A CA  1 
ATOM 3085 C C   . ASP A 1 384  ? 120.746 99.621  90.396  1.00 63.08  ? 384  ASP A C   1 
ATOM 3086 O O   . ASP A 1 384  ? 120.494 98.603  91.022  1.00 66.11  ? 384  ASP A O   1 
ATOM 3087 C CB  . ASP A 1 384  ? 122.340 101.246 91.491  1.00 113.93 ? 384  ASP A CB  1 
ATOM 3088 C CG  . ASP A 1 384  ? 123.797 101.567 91.796  1.00 136.14 ? 384  ASP A CG  1 
ATOM 3089 O OD1 . ASP A 1 384  ? 124.683 101.011 91.104  1.00 139.01 ? 384  ASP A OD1 1 
ATOM 3090 O OD2 . ASP A 1 384  ? 124.040 102.365 92.729  1.00 150.70 ? 384  ASP A OD2 1 
ATOM 3091 N N   . VAL A 1 385  ? 119.814 100.271 89.706  1.00 52.54  ? 385  VAL A N   1 
ATOM 3092 C CA  . VAL A 1 385  ? 118.490 99.686  89.629  1.00 53.69  ? 385  VAL A CA  1 
ATOM 3093 C C   . VAL A 1 385  ? 118.630 98.316  88.991  1.00 59.43  ? 385  VAL A C   1 
ATOM 3094 O O   . VAL A 1 385  ? 117.984 97.381  89.443  1.00 69.03  ? 385  VAL A O   1 
ATOM 3095 C CB  . VAL A 1 385  ? 117.467 100.528 88.851  1.00 61.97  ? 385  VAL A CB  1 
ATOM 3096 C CG1 . VAL A 1 385  ? 116.139 99.798  88.721  1.00 57.97  ? 385  VAL A CG1 1 
ATOM 3097 C CG2 . VAL A 1 385  ? 117.273 101.893 89.486  1.00 74.86  ? 385  VAL A CG2 1 
ATOM 3098 N N   . VAL A 1 386  ? 119.497 98.194  87.976  1.00 66.97  ? 386  VAL A N   1 
ATOM 3099 C CA  . VAL A 1 386  ? 119.581 96.967  87.197  1.00 75.87  ? 386  VAL A CA  1 
ATOM 3100 C C   . VAL A 1 386  ? 120.170 95.839  88.037  1.00 76.57  ? 386  VAL A C   1 
ATOM 3101 O O   . VAL A 1 386  ? 119.603 94.753  88.041  1.00 75.35  ? 386  VAL A O   1 
ATOM 3102 C CB  . VAL A 1 386  ? 120.331 97.149  85.860  1.00 90.16  ? 386  VAL A CB  1 
ATOM 3103 C CG1 . VAL A 1 386  ? 121.587 96.290  85.748  1.00 98.55  ? 386  VAL A CG1 1 
ATOM 3104 C CG2 . VAL A 1 386  ? 119.409 96.906  84.668  1.00 92.23  ? 386  VAL A CG2 1 
ATOM 3105 N N   . GLN A 1 387  ? 121.293 96.069  88.732  1.00 75.85  ? 387  GLN A N   1 
ATOM 3106 C CA  . GLN A 1 387  ? 121.861 95.012  89.559  1.00 72.78  ? 387  GLN A CA  1 
ATOM 3107 C C   . GLN A 1 387  ? 120.764 94.485  90.475  1.00 64.50  ? 387  GLN A C   1 
ATOM 3108 O O   . GLN A 1 387  ? 120.509 93.288  90.531  1.00 67.27  ? 387  GLN A O   1 
ATOM 3109 C CB  . GLN A 1 387  ? 123.033 95.495  90.414  1.00 75.20  ? 387  GLN A CB  1 
ATOM 3110 C CG  . GLN A 1 387  ? 123.973 94.372  90.828  1.00 83.04  ? 387  GLN A CG  1 
ATOM 3111 C CD  . GLN A 1 387  ? 124.980 94.067  89.744  1.00 99.57  ? 387  GLN A CD  1 
ATOM 3112 O OE1 . GLN A 1 387  ? 125.805 94.905  89.383  1.00 107.51 ? 387  GLN A OE1 1 
ATOM 3113 N NE2 . GLN A 1 387  ? 124.928 92.856  89.212  1.00 110.73 ? 387  GLN A NE2 1 
ATOM 3114 N N   . ALA A 1 388  ? 120.080 95.429  91.121  1.00 59.28  ? 388  ALA A N   1 
ATOM 3115 C CA  . ALA A 1 388  ? 119.049 95.147  92.098  1.00 61.17  ? 388  ALA A CA  1 
ATOM 3116 C C   . ALA A 1 388  ? 117.869 94.403  91.479  1.00 55.25  ? 388  ALA A C   1 
ATOM 3117 O O   . ALA A 1 388  ? 117.287 93.553  92.140  1.00 65.32  ? 388  ALA A O   1 
ATOM 3118 C CB  . ALA A 1 388  ? 118.593 96.436  92.745  1.00 69.85  ? 388  ALA A CB  1 
ATOM 3119 N N   . ILE A 1 389  ? 117.460 94.717  90.249  1.00 49.11  ? 389  ILE A N   1 
ATOM 3120 C CA  . ILE A 1 389  ? 116.333 93.971  89.720  1.00 53.75  ? 389  ILE A CA  1 
ATOM 3121 C C   . ILE A 1 389  ? 116.767 92.511  89.638  1.00 61.19  ? 389  ILE A C   1 
ATOM 3122 O O   . ILE A 1 389  ? 116.025 91.633  90.059  1.00 64.99  ? 389  ILE A O   1 
ATOM 3123 C CB  . ILE A 1 389  ? 115.790 94.479  88.373  1.00 59.65  ? 389  ILE A CB  1 
ATOM 3124 C CG1 . ILE A 1 389  ? 115.666 96.002  88.316  1.00 71.17  ? 389  ILE A CG1 1 
ATOM 3125 C CG2 . ILE A 1 389  ? 114.448 93.813  88.075  1.00 58.24  ? 389  ILE A CG2 1 
ATOM 3126 C CD1 . ILE A 1 389  ? 115.607 96.556  86.902  1.00 80.65  ? 389  ILE A CD1 1 
ATOM 3127 N N   . LYS A 1 390  ? 118.001 92.270  89.176  1.00 69.58  ? 390  LYS A N   1 
ATOM 3128 C CA  . LYS A 1 390  ? 118.480 90.919  88.914  1.00 76.83  ? 390  LYS A CA  1 
ATOM 3129 C C   . LYS A 1 390  ? 118.537 90.080  90.183  1.00 76.90  ? 390  LYS A C   1 
ATOM 3130 O O   . LYS A 1 390  ? 118.044 88.955  90.193  1.00 84.07  ? 390  LYS A O   1 
ATOM 3131 C CB  . LYS A 1 390  ? 119.917 90.903  88.387  1.00 88.01  ? 390  LYS A CB  1 
ATOM 3132 C CG  . LYS A 1 390  ? 120.444 89.512  88.051  1.00 101.16 ? 390  LYS A CG  1 
ATOM 3133 C CD  . LYS A 1 390  ? 121.823 89.217  88.606  1.00 111.35 ? 390  LYS A CD  1 
ATOM 3134 C CE  . LYS A 1 390  ? 122.871 90.239  88.218  1.00 117.76 ? 390  LYS A CE  1 
ATOM 3135 N NZ  . LYS A 1 390  ? 124.230 89.818  88.638  1.00 120.58 ? 390  LYS A NZ  1 
ATOM 3136 N N   . ASP A 1 391  ? 119.222 90.605  91.203  1.00 77.91  ? 391  ASP A N   1 
ATOM 3137 C CA  . ASP A 1 391  ? 119.614 89.815  92.358  1.00 86.30  ? 391  ASP A CA  1 
ATOM 3138 C C   . ASP A 1 391  ? 118.383 89.358  93.135  1.00 82.03  ? 391  ASP A C   1 
ATOM 3139 O O   . ASP A 1 391  ? 118.311 88.195  93.519  1.00 97.60  ? 391  ASP A O   1 
ATOM 3140 C CB  . ASP A 1 391  ? 120.598 90.569  93.255  1.00 101.96 ? 391  ASP A CB  1 
ATOM 3141 C CG  . ASP A 1 391  ? 122.026 90.530  92.735  1.00 128.68 ? 391  ASP A CG  1 
ATOM 3142 O OD1 . ASP A 1 391  ? 122.246 90.971  91.580  1.00 141.92 ? 391  ASP A OD1 1 
ATOM 3143 O OD2 . ASP A 1 391  ? 122.910 90.052  93.483  1.00 139.70 ? 391  ASP A OD2 1 
ATOM 3144 N N   . HIS A 1 392  ? 117.419 90.261  93.339  1.00 65.59  ? 392  HIS A N   1 
ATOM 3145 C CA  . HIS A 1 392  ? 116.279 89.976  94.187  1.00 56.11  ? 392  HIS A CA  1 
ATOM 3146 C C   . HIS A 1 392  ? 115.027 89.707  93.367  1.00 47.01  ? 392  HIS A C   1 
ATOM 3147 O O   . HIS A 1 392  ? 113.943 89.672  93.935  1.00 54.09  ? 392  HIS A O   1 
ATOM 3148 C CB  . HIS A 1 392  ? 115.995 91.155  95.123  1.00 62.79  ? 392  HIS A CB  1 
ATOM 3149 C CG  . HIS A 1 392  ? 117.160 91.567  95.949  1.00 73.24  ? 392  HIS A CG  1 
ATOM 3150 N ND1 . HIS A 1 392  ? 117.120 91.575  97.326  1.00 89.85  ? 392  HIS A ND1 1 
ATOM 3151 C CD2 . HIS A 1 392  ? 118.385 91.984  95.612  1.00 81.98  ? 392  HIS A CD2 1 
ATOM 3152 C CE1 . HIS A 1 392  ? 118.294 91.973  97.793  1.00 97.02  ? 392  HIS A CE1 1 
ATOM 3153 N NE2 . HIS A 1 392  ? 119.076 92.230  96.766  1.00 93.90  ? 392  HIS A NE2 1 
ATOM 3154 N N   . ALA A 1 393  ? 115.151 89.532  92.052  1.00 44.24  ? 393  ALA A N   1 
ATOM 3155 C CA  . ALA A 1 393  ? 113.964 89.502  91.212  1.00 53.02  ? 393  ALA A CA  1 
ATOM 3156 C C   . ALA A 1 393  ? 113.156 88.235  91.455  1.00 52.22  ? 393  ALA A C   1 
ATOM 3157 O O   . ALA A 1 393  ? 111.939 88.302  91.613  1.00 46.53  ? 393  ALA A O   1 
ATOM 3158 C CB  . ALA A 1 393  ? 114.310 89.618  89.747  1.00 61.93  ? 393  ALA A CB  1 
ATOM 3159 N N   . PHE A 1 394  ? 113.830 87.080  91.430  1.00 61.93  ? 394  PHE A N   1 
ATOM 3160 C CA  . PHE A 1 394  ? 113.116 85.814  91.452  1.00 78.95  ? 394  PHE A CA  1 
ATOM 3161 C C   . PHE A 1 394  ? 113.383 85.017  92.733  1.00 95.77  ? 394  PHE A C   1 
ATOM 3162 O O   . PHE A 1 394  ? 113.201 83.799  92.750  1.00 103.33 ? 394  PHE A O   1 
ATOM 3163 C CB  . PHE A 1 394  ? 113.483 84.961  90.238  1.00 82.80  ? 394  PHE A CB  1 
ATOM 3164 C CG  . PHE A 1 394  ? 113.120 85.544  88.900  1.00 83.86  ? 394  PHE A CG  1 
ATOM 3165 C CD1 . PHE A 1 394  ? 111.802 85.824  88.582  1.00 90.08  ? 394  PHE A CD1 1 
ATOM 3166 C CD2 . PHE A 1 394  ? 114.100 85.787  87.951  1.00 87.98  ? 394  PHE A CD2 1 
ATOM 3167 C CE1 . PHE A 1 394  ? 111.470 86.354  87.346  1.00 102.35 ? 394  PHE A CE1 1 
ATOM 3168 C CE2 . PHE A 1 394  ? 113.767 86.316  86.716  1.00 96.67  ? 394  PHE A CE2 1 
ATOM 3169 C CZ  . PHE A 1 394  ? 112.456 86.612  86.424  1.00 107.00 ? 394  PHE A CZ  1 
ATOM 3170 N N   . VAL A 1 395  ? 113.756 85.702  93.820  1.00 91.37  ? 395  VAL A N   1 
ATOM 3171 C CA  . VAL A 1 395  ? 113.975 85.054  95.103  1.00 76.63  ? 395  VAL A CA  1 
ATOM 3172 C C   . VAL A 1 395  ? 112.639 84.598  95.678  1.00 67.05  ? 395  VAL A C   1 
ATOM 3173 O O   . VAL A 1 395  ? 112.487 83.430  96.009  1.00 71.27  ? 395  VAL A O   1 
ATOM 3174 C CB  . VAL A 1 395  ? 114.716 85.981  96.080  1.00 85.32  ? 395  VAL A CB  1 
ATOM 3175 C CG1 . VAL A 1 395  ? 114.544 85.548  97.530  1.00 95.89  ? 395  VAL A CG1 1 
ATOM 3176 C CG2 . VAL A 1 395  ? 116.188 86.075  95.717  1.00 90.94  ? 395  VAL A CG2 1 
ATOM 3177 N N   . THR A 1 396  ? 111.693 85.523  95.834  1.00 64.65  ? 396  THR A N   1 
ATOM 3178 C CA  . THR A 1 396  ? 110.416 85.172  96.422  1.00 70.39  ? 396  THR A CA  1 
ATOM 3179 C C   . THR A 1 396  ? 109.686 84.197  95.513  1.00 66.86  ? 396  THR A C   1 
ATOM 3180 O O   . THR A 1 396  ? 109.092 83.237  96.000  1.00 73.47  ? 396  THR A O   1 
ATOM 3181 C CB  . THR A 1 396  ? 109.509 86.386  96.643  1.00 89.44  ? 396  THR A CB  1 
ATOM 3182 O OG1 . THR A 1 396  ? 110.091 87.217  97.652  1.00 100.82 ? 396  THR A OG1 1 
ATOM 3183 C CG2 . THR A 1 396  ? 108.102 85.995  97.050  1.00 93.15  ? 396  THR A CG2 1 
ATOM 3184 N N   . SER A 1 397  ? 109.715 84.473  94.204  1.00 66.58  ? 397  SER A N   1 
ATOM 3185 C CA  . SER A 1 397  ? 108.914 83.718  93.254  1.00 75.41  ? 397  SER A CA  1 
ATOM 3186 C C   . SER A 1 397  ? 109.621 83.573  91.909  1.00 74.68  ? 397  SER A C   1 
ATOM 3187 O O   . SER A 1 397  ? 110.196 84.521  91.402  1.00 69.41  ? 397  SER A O   1 
ATOM 3188 C CB  . SER A 1 397  ? 107.563 84.356  93.071  1.00 80.11  ? 397  SER A CB  1 
ATOM 3189 O OG  . SER A 1 397  ? 106.812 83.633  92.107  1.00 83.65  ? 397  SER A OG  1 
ATOM 3190 N N   . SER A 1 398  ? 109.485 82.403  91.283  1.00 80.54  ? 398  SER A N   1 
ATOM 3191 C CA  . SER A 1 398  ? 110.232 82.108  90.075  1.00 80.56  ? 398  SER A CA  1 
ATOM 3192 C C   . SER A 1 398  ? 109.520 82.628  88.827  1.00 72.92  ? 398  SER A C   1 
ATOM 3193 O O   . SER A 1 398  ? 110.179 82.873  87.820  1.00 81.78  ? 398  SER A O   1 
ATOM 3194 C CB  . SER A 1 398  ? 110.494 80.632  89.970  1.00 94.16  ? 398  SER A CB  1 
ATOM 3195 O OG  . SER A 1 398  ? 109.272 79.904  89.959  1.00 100.76 ? 398  SER A OG  1 
ATOM 3196 N N   . PHE A 1 399  ? 108.194 82.815  88.885  1.00 60.72  ? 399  PHE A N   1 
ATOM 3197 C CA  . PHE A 1 399  ? 107.420 83.202  87.711  1.00 61.36  ? 399  PHE A CA  1 
ATOM 3198 C C   . PHE A 1 399  ? 107.886 84.571  87.189  1.00 60.56  ? 399  PHE A C   1 
ATOM 3199 O O   . PHE A 1 399  ? 108.602 85.263  87.898  1.00 69.26  ? 399  PHE A O   1 
ATOM 3200 C CB  . PHE A 1 399  ? 105.941 83.091  88.074  1.00 60.52  ? 399  PHE A CB  1 
ATOM 3201 C CG  . PHE A 1 399  ? 105.535 81.693  88.447  1.00 61.88  ? 399  PHE A CG  1 
ATOM 3202 C CD1 . PHE A 1 399  ? 106.445 80.652  88.386  1.00 68.06  ? 399  PHE A CD1 1 
ATOM 3203 C CD2 . PHE A 1 399  ? 104.239 81.419  88.845  1.00 69.45  ? 399  PHE A CD2 1 
ATOM 3204 C CE1 . PHE A 1 399  ? 106.065 79.365  88.727  1.00 87.26  ? 399  PHE A CE1 1 
ATOM 3205 C CE2 . PHE A 1 399  ? 103.871 80.138  89.209  1.00 76.76  ? 399  PHE A CE2 1 
ATOM 3206 C CZ  . PHE A 1 399  ? 104.777 79.111  89.137  1.00 87.54  ? 399  PHE A CZ  1 
ATOM 3207 N N   . PRO A 1 400  ? 107.575 84.979  85.929  1.00 42.91  ? 400  PRO A N   1 
ATOM 3208 C CA  . PRO A 1 400  ? 108.277 86.088  85.258  1.00 36.89  ? 400  PRO A CA  1 
ATOM 3209 C C   . PRO A 1 400  ? 107.969 87.562  85.523  1.00 36.45  ? 400  PRO A C   1 
ATOM 3210 O O   . PRO A 1 400  ? 106.808 87.955  85.536  1.00 38.13  ? 400  PRO A O   1 
ATOM 3211 C CB  . PRO A 1 400  ? 107.824 85.934  83.803  1.00 38.38  ? 400  PRO A CB  1 
ATOM 3212 C CG  . PRO A 1 400  ? 106.460 85.308  83.903  1.00 40.07  ? 400  PRO A CG  1 
ATOM 3213 C CD  . PRO A 1 400  ? 106.578 84.338  85.054  1.00 40.27  ? 400  PRO A CD  1 
ATOM 3214 N N   . VAL A 1 401  ? 109.025 88.392  85.616  1.00 35.88  ? 401  VAL A N   1 
ATOM 3215 C CA  . VAL A 1 401  ? 108.896 89.838  85.740  1.00 37.46  ? 401  VAL A CA  1 
ATOM 3216 C C   . VAL A 1 401  ? 108.493 90.417  84.386  1.00 40.83  ? 401  VAL A C   1 
ATOM 3217 O O   . VAL A 1 401  ? 108.877 89.859  83.364  1.00 48.74  ? 401  VAL A O   1 
ATOM 3218 C CB  . VAL A 1 401  ? 110.218 90.462  86.214  1.00 43.68  ? 401  VAL A CB  1 
ATOM 3219 C CG1 . VAL A 1 401  ? 110.157 91.988  86.233  1.00 49.83  ? 401  VAL A CG1 1 
ATOM 3220 C CG2 . VAL A 1 401  ? 110.631 89.931  87.577  1.00 47.66  ? 401  VAL A CG2 1 
ATOM 3221 N N   . ILE A 1 402  ? 107.733 91.531  84.368  1.00 37.39  ? 402  ILE A N   1 
ATOM 3222 C CA  . ILE A 1 402  ? 107.343 92.184  83.124  1.00 32.99  ? 402  ILE A CA  1 
ATOM 3223 C C   . ILE A 1 402  ? 107.742 93.653  83.164  1.00 29.95  ? 402  ILE A C   1 
ATOM 3224 O O   . ILE A 1 402  ? 106.906 94.524  82.970  1.00 28.58  ? 402  ILE A O   1 
ATOM 3225 C CB  . ILE A 1 402  ? 105.847 91.991  82.820  1.00 33.38  ? 402  ILE A CB  1 
ATOM 3226 C CG1 . ILE A 1 402  ? 105.492 90.505  82.857  1.00 40.40  ? 402  ILE A CG1 1 
ATOM 3227 C CG2 . ILE A 1 402  ? 105.506 92.617  81.479  1.00 36.23  ? 402  ILE A CG2 1 
ATOM 3228 C CD1 . ILE A 1 402  ? 104.047 90.180  82.570  1.00 46.43  ? 402  ILE A CD1 1 
ATOM 3229 N N   . LEU A 1 403  ? 109.038 93.899  83.360  1.00 31.69  ? 403  LEU A N   1 
ATOM 3230 C CA  . LEU A 1 403  ? 109.583 95.244  83.402  1.00 37.24  ? 403  LEU A CA  1 
ATOM 3231 C C   . LEU A 1 403  ? 108.980 96.073  82.264  1.00 47.06  ? 403  LEU A C   1 
ATOM 3232 O O   . LEU A 1 403  ? 108.809 95.570  81.151  1.00 56.03  ? 403  LEU A O   1 
ATOM 3233 C CB  . LEU A 1 403  ? 111.106 95.141  83.283  1.00 39.11  ? 403  LEU A CB  1 
ATOM 3234 C CG  . LEU A 1 403  ? 111.897 96.052  84.214  1.00 47.29  ? 403  LEU A CG  1 
ATOM 3235 C CD1 . LEU A 1 403  ? 113.387 95.912  83.950  1.00 48.98  ? 403  LEU A CD1 1 
ATOM 3236 C CD2 . LEU A 1 403  ? 111.447 97.502  84.066  1.00 51.17  ? 403  LEU A CD2 1 
ATOM 3237 N N   . SER A 1 404  ? 108.649 97.344  82.543  1.00 50.48  ? 404  SER A N   1 
ATOM 3238 C CA  . SER A 1 404  ? 107.950 98.187  81.585  1.00 52.72  ? 404  SER A CA  1 
ATOM 3239 C C   . SER A 1 404  ? 108.652 99.523  81.409  1.00 50.89  ? 404  SER A C   1 
ATOM 3240 O O   . SER A 1 404  ? 108.110 100.555 81.794  1.00 53.54  ? 404  SER A O   1 
ATOM 3241 C CB  . SER A 1 404  ? 106.518 98.400  82.002  1.00 54.81  ? 404  SER A CB  1 
ATOM 3242 O OG  . SER A 1 404  ? 105.942 99.461  81.250  1.00 59.18  ? 404  SER A OG  1 
ATOM 3243 N N   . ILE A 1 405  ? 109.821 99.506  80.769  1.00 54.98  ? 405  ILE A N   1 
ATOM 3244 C CA  . ILE A 1 405  ? 110.561 100.741 80.582  1.00 66.25  ? 405  ILE A CA  1 
ATOM 3245 C C   . ILE A 1 405  ? 109.669 101.717 79.817  1.00 80.51  ? 405  ILE A C   1 
ATOM 3246 O O   . ILE A 1 405  ? 108.995 101.325 78.863  1.00 88.58  ? 405  ILE A O   1 
ATOM 3247 C CB  . ILE A 1 405  ? 111.905 100.525 79.856  1.00 73.36  ? 405  ILE A CB  1 
ATOM 3248 C CG1 . ILE A 1 405  ? 112.719 99.353  80.419  1.00 84.66  ? 405  ILE A CG1 1 
ATOM 3249 C CG2 . ILE A 1 405  ? 112.710 101.816 79.887  1.00 71.36  ? 405  ILE A CG2 1 
ATOM 3250 C CD1 . ILE A 1 405  ? 113.196 99.581  81.837  1.00 89.68  ? 405  ILE A CD1 1 
ATOM 3251 N N   . GLU A 1 406  ? 109.624 102.965 80.298  1.00 96.70  ? 406  GLU A N   1 
ATOM 3252 C CA  . GLU A 1 406  ? 109.191 104.105 79.509  1.00 110.54 ? 406  GLU A CA  1 
ATOM 3253 C C   . GLU A 1 406  ? 110.397 105.024 79.376  1.00 108.95 ? 406  GLU A C   1 
ATOM 3254 O O   . GLU A 1 406  ? 111.009 105.366 80.383  1.00 110.71 ? 406  GLU A O   1 
ATOM 3255 C CB  . GLU A 1 406  ? 108.034 104.839 80.189  1.00 123.78 ? 406  GLU A CB  1 
ATOM 3256 C CG  . GLU A 1 406  ? 107.802 106.241 79.647  1.00 140.36 ? 406  GLU A CG  1 
ATOM 3257 C CD  . GLU A 1 406  ? 106.990 107.144 80.559  1.00 163.70 ? 406  GLU A CD  1 
ATOM 3258 O OE1 . GLU A 1 406  ? 105.902 107.582 80.137  1.00 177.15 ? 406  GLU A OE1 1 
ATOM 3259 O OE2 . GLU A 1 406  ? 107.456 107.420 81.683  1.00 176.86 ? 406  GLU A OE2 1 
ATOM 3260 N N   . GLU A 1 407  ? 110.753 105.402 78.144  1.00 104.64 ? 407  GLU A N   1 
ATOM 3261 C CA  . GLU A 1 407  ? 112.013 106.090 77.937  1.00 105.93 ? 407  GLU A CA  1 
ATOM 3262 C C   . GLU A 1 407  ? 111.762 107.492 77.400  1.00 104.43 ? 407  GLU A C   1 
ATOM 3263 O O   . GLU A 1 407  ? 111.166 107.666 76.341  1.00 118.00 ? 407  GLU A O   1 
ATOM 3264 C CB  . GLU A 1 407  ? 112.893 105.295 76.979  1.00 111.97 ? 407  GLU A CB  1 
ATOM 3265 C CG  . GLU A 1 407  ? 114.297 105.087 77.498  1.00 125.87 ? 407  GLU A CG  1 
ATOM 3266 C CD  . GLU A 1 407  ? 115.389 105.029 76.449  1.00 151.95 ? 407  GLU A CD  1 
ATOM 3267 O OE1 . GLU A 1 407  ? 116.499 104.584 76.799  1.00 159.77 ? 407  GLU A OE1 1 
ATOM 3268 O OE2 . GLU A 1 407  ? 115.144 105.482 75.313  1.00 161.20 ? 407  GLU A OE2 1 
ATOM 3269 N N   . HIS A 1 408  ? 112.233 108.480 78.159  1.00 94.89  ? 408  HIS A N   1 
ATOM 3270 C CA  . HIS A 1 408  ? 112.352 109.833 77.663  1.00 93.12  ? 408  HIS A CA  1 
ATOM 3271 C C   . HIS A 1 408  ? 113.805 110.026 77.248  1.00 82.13  ? 408  HIS A C   1 
ATOM 3272 O O   . HIS A 1 408  ? 114.192 111.109 76.823  1.00 93.02  ? 408  HIS A O   1 
ATOM 3273 C CB  . HIS A 1 408  ? 111.821 110.814 78.716  1.00 97.44  ? 408  HIS A CB  1 
ATOM 3274 C CG  . HIS A 1 408  ? 110.444 110.472 79.185  1.00 101.08 ? 408  HIS A CG  1 
ATOM 3275 N ND1 . HIS A 1 408  ? 109.353 111.263 78.900  1.00 112.53 ? 408  HIS A ND1 1 
ATOM 3276 C CD2 . HIS A 1 408  ? 109.973 109.428 79.884  1.00 106.14 ? 408  HIS A CD2 1 
ATOM 3277 C CE1 . HIS A 1 408  ? 108.268 110.714 79.425  1.00 121.07 ? 408  HIS A CE1 1 
ATOM 3278 N NE2 . HIS A 1 408  ? 108.624 109.601 80.031  1.00 116.63 ? 408  HIS A NE2 1 
ATOM 3279 N N   . CYS A 1 409  ? 114.590 108.952 77.339  1.00 75.74  ? 409  CYS A N   1 
ATOM 3280 C CA  . CYS A 1 409  ? 116.028 109.051 77.167  1.00 96.31  ? 409  CYS A CA  1 
ATOM 3281 C C   . CYS A 1 409  ? 116.386 109.270 75.699  1.00 104.51 ? 409  CYS A C   1 
ATOM 3282 O O   . CYS A 1 409  ? 115.693 108.786 74.804  1.00 107.70 ? 409  CYS A O   1 
ATOM 3283 C CB  . CYS A 1 409  ? 116.725 107.793 77.667  1.00 122.01 ? 409  CYS A CB  1 
ATOM 3284 S SG  . CYS A 1 409  ? 116.699 107.615 79.470  1.00 155.16 ? 409  CYS A SG  1 
ATOM 3285 N N   . SER A 1 410  ? 117.499 109.984 75.475  1.00 108.59 ? 410  SER A N   1 
ATOM 3286 C CA  . SER A 1 410  ? 118.043 110.202 74.141  1.00 113.91 ? 410  SER A CA  1 
ATOM 3287 C C   . SER A 1 410  ? 118.699 108.923 73.637  1.00 116.76 ? 410  SER A C   1 
ATOM 3288 O O   . SER A 1 410  ? 119.062 108.068 74.437  1.00 127.54 ? 410  SER A O   1 
ATOM 3289 C CB  . SER A 1 410  ? 119.053 111.316 74.125  1.00 117.99 ? 410  SER A CB  1 
ATOM 3290 O OG  . SER A 1 410  ? 120.346 110.819 74.448  1.00 113.54 ? 410  SER A OG  1 
ATOM 3291 N N   . VAL A 1 411  ? 118.949 108.868 72.324  1.00 117.33 ? 411  VAL A N   1 
ATOM 3292 C CA  . VAL A 1 411  ? 119.376 107.644 71.656  1.00 118.05 ? 411  VAL A CA  1 
ATOM 3293 C C   . VAL A 1 411  ? 120.751 107.199 72.149  1.00 114.62 ? 411  VAL A C   1 
ATOM 3294 O O   . VAL A 1 411  ? 120.959 106.007 72.353  1.00 118.81 ? 411  VAL A O   1 
ATOM 3295 C CB  . VAL A 1 411  ? 119.362 107.736 70.115  1.00 131.07 ? 411  VAL A CB  1 
ATOM 3296 C CG1 . VAL A 1 411  ? 118.439 106.691 69.513  1.00 133.28 ? 411  VAL A CG1 1 
ATOM 3297 C CG2 . VAL A 1 411  ? 119.031 109.126 69.577  1.00 141.92 ? 411  VAL A CG2 1 
ATOM 3298 N N   . GLU A 1 412  ? 121.687 108.138 72.323  1.00 114.02 ? 412  GLU A N   1 
ATOM 3299 C CA  . GLU A 1 412  ? 123.032 107.782 72.744  1.00 118.21 ? 412  GLU A CA  1 
ATOM 3300 C C   . GLU A 1 412  ? 122.983 107.102 74.110  1.00 112.79 ? 412  GLU A C   1 
ATOM 3301 O O   . GLU A 1 412  ? 123.674 106.111 74.335  1.00 107.65 ? 412  GLU A O   1 
ATOM 3302 C CB  . GLU A 1 412  ? 123.937 109.014 72.773  1.00 133.29 ? 412  GLU A CB  1 
ATOM 3303 C CG  . GLU A 1 412  ? 125.377 108.685 73.124  1.00 149.23 ? 412  GLU A CG  1 
ATOM 3304 C CD  . GLU A 1 412  ? 125.910 107.440 72.434  1.00 164.99 ? 412  GLU A CD  1 
ATOM 3305 O OE1 . GLU A 1 412  ? 126.297 106.491 73.146  1.00 175.40 ? 412  GLU A OE1 1 
ATOM 3306 O OE2 . GLU A 1 412  ? 125.910 107.413 71.186  1.00 170.73 ? 412  GLU A OE2 1 
ATOM 3307 N N   . GLN A 1 413  ? 122.126 107.624 74.995  1.00 113.58 ? 413  GLN A N   1 
ATOM 3308 C CA  . GLN A 1 413  ? 121.973 107.103 76.345  1.00 109.69 ? 413  GLN A CA  1 
ATOM 3309 C C   . GLN A 1 413  ? 121.274 105.744 76.305  1.00 102.19 ? 413  GLN A C   1 
ATOM 3310 O O   . GLN A 1 413  ? 121.606 104.859 77.089  1.00 108.68 ? 413  GLN A O   1 
ATOM 3311 C CB  . GLN A 1 413  ? 121.179 108.080 77.220  1.00 115.58 ? 413  GLN A CB  1 
ATOM 3312 C CG  . GLN A 1 413  ? 121.677 109.523 77.190  1.00 129.03 ? 413  GLN A CG  1 
ATOM 3313 C CD  . GLN A 1 413  ? 123.077 109.719 77.724  1.00 137.95 ? 413  GLN A CD  1 
ATOM 3314 O OE1 . GLN A 1 413  ? 123.287 110.364 78.751  1.00 140.94 ? 413  GLN A OE1 1 
ATOM 3315 N NE2 . GLN A 1 413  ? 124.058 109.190 77.010  1.00 140.48 ? 413  GLN A NE2 1 
ATOM 3316 N N   . GLN A 1 414  ? 120.305 105.588 75.394  1.00 90.42  ? 414  GLN A N   1 
ATOM 3317 C CA  . GLN A 1 414  ? 119.506 104.377 75.310  1.00 82.21  ? 414  GLN A CA  1 
ATOM 3318 C C   . GLN A 1 414  ? 120.410 103.176 75.069  1.00 86.03  ? 414  GLN A C   1 
ATOM 3319 O O   . GLN A 1 414  ? 120.176 102.113 75.631  1.00 93.83  ? 414  GLN A O   1 
ATOM 3320 C CB  . GLN A 1 414  ? 118.453 104.506 74.212  1.00 80.00  ? 414  GLN A CB  1 
ATOM 3321 C CG  . GLN A 1 414  ? 117.519 103.309 74.089  1.00 88.28  ? 414  GLN A CG  1 
ATOM 3322 C CD  . GLN A 1 414  ? 116.229 103.686 73.394  1.00 104.83 ? 414  GLN A CD  1 
ATOM 3323 O OE1 . GLN A 1 414  ? 115.376 102.844 73.109  1.00 112.17 ? 414  GLN A OE1 1 
ATOM 3324 N NE2 . GLN A 1 414  ? 116.071 104.972 73.114  1.00 104.80 ? 414  GLN A NE2 1 
ATOM 3325 N N   . ARG A 1 415  ? 121.456 103.357 74.258  1.00 94.40  ? 415  ARG A N   1 
ATOM 3326 C CA  . ARG A 1 415  ? 122.350 102.260 73.930  1.00 112.72 ? 415  ARG A CA  1 
ATOM 3327 C C   . ARG A 1 415  ? 122.925 101.667 75.211  1.00 101.15 ? 415  ARG A C   1 
ATOM 3328 O O   . ARG A 1 415  ? 122.848 100.459 75.413  1.00 108.56 ? 415  ARG A O   1 
ATOM 3329 C CB  . ARG A 1 415  ? 123.449 102.717 72.967  1.00 145.54 ? 415  ARG A CB  1 
ATOM 3330 C CG  . ARG A 1 415  ? 122.921 103.057 71.579  1.00 170.31 ? 415  ARG A CG  1 
ATOM 3331 C CD  . ARG A 1 415  ? 123.997 103.408 70.569  1.00 185.68 ? 415  ARG A CD  1 
ATOM 3332 N NE  . ARG A 1 415  ? 123.426 103.790 69.284  1.00 199.38 ? 415  ARG A NE  1 
ATOM 3333 C CZ  . ARG A 1 415  ? 124.121 104.277 68.262  1.00 223.99 ? 415  ARG A CZ  1 
ATOM 3334 N NH1 . ARG A 1 415  ? 125.429 104.437 68.365  1.00 232.85 ? 415  ARG A NH1 1 
ATOM 3335 N NH2 . ARG A 1 415  ? 123.505 104.604 67.139  1.00 233.09 ? 415  ARG A NH2 1 
ATOM 3336 N N   . HIS A 1 416  ? 123.480 102.512 76.082  1.00 91.33  ? 416  HIS A N   1 
ATOM 3337 C CA  . HIS A 1 416  ? 124.049 102.007 77.319  1.00 90.87  ? 416  HIS A CA  1 
ATOM 3338 C C   . HIS A 1 416  ? 123.025 101.116 78.008  1.00 76.13  ? 416  HIS A C   1 
ATOM 3339 O O   . HIS A 1 416  ? 123.355 100.037 78.475  1.00 79.05  ? 416  HIS A O   1 
ATOM 3340 C CB  . HIS A 1 416  ? 124.462 103.122 78.282  1.00 108.00 ? 416  HIS A CB  1 
ATOM 3341 C CG  . HIS A 1 416  ? 125.193 102.590 79.471  1.00 126.06 ? 416  HIS A CG  1 
ATOM 3342 N ND1 . HIS A 1 416  ? 126.505 102.178 79.391  1.00 140.30 ? 416  HIS A ND1 1 
ATOM 3343 C CD2 . HIS A 1 416  ? 124.815 102.388 80.743  1.00 136.99 ? 416  HIS A CD2 1 
ATOM 3344 C CE1 . HIS A 1 416  ? 126.897 101.744 80.580  1.00 154.35 ? 416  HIS A CE1 1 
ATOM 3345 N NE2 . HIS A 1 416  ? 125.887 101.867 81.418  1.00 149.86 ? 416  HIS A NE2 1 
ATOM 3346 N N   . MET A 1 417  ? 121.780 101.581 78.053  1.00 73.06  ? 417  MET A N   1 
ATOM 3347 C CA  . MET A 1 417  ? 120.707 100.820 78.665  1.00 81.27  ? 417  MET A CA  1 
ATOM 3348 C C   . MET A 1 417  ? 120.646 99.409  78.086  1.00 84.00  ? 417  MET A C   1 
ATOM 3349 O O   . MET A 1 417  ? 120.649 98.434  78.837  1.00 94.87  ? 417  MET A O   1 
ATOM 3350 C CB  . MET A 1 417  ? 119.357 101.506 78.450  1.00 87.89  ? 417  MET A CB  1 
ATOM 3351 C CG  . MET A 1 417  ? 118.653 101.863 79.732  1.00 94.39  ? 417  MET A CG  1 
ATOM 3352 S SD  . MET A 1 417  ? 117.071 102.638 79.379  1.00 106.20 ? 417  MET A SD  1 
ATOM 3353 C CE  . MET A 1 417  ? 116.131 101.211 78.835  1.00 104.82 ? 417  MET A CE  1 
ATOM 3354 N N   . ALA A 1 418  ? 120.589 99.302  76.755  1.00 82.81  ? 418  ALA A N   1 
ATOM 3355 C CA  . ALA A 1 418  ? 120.371 98.014  76.114  1.00 81.98  ? 418  ALA A CA  1 
ATOM 3356 C C   . ALA A 1 418  ? 121.541 97.083  76.408  1.00 77.08  ? 418  ALA A C   1 
ATOM 3357 O O   . ALA A 1 418  ? 121.328 95.941  76.803  1.00 80.87  ? 418  ALA A O   1 
ATOM 3358 C CB  . ALA A 1 418  ? 120.167 98.182  74.631  1.00 88.33  ? 418  ALA A CB  1 
ATOM 3359 N N   . LYS A 1 419  ? 122.770 97.574  76.218  1.00 75.82  ? 419  LYS A N   1 
ATOM 3360 C CA  . LYS A 1 419  ? 123.936 96.765  76.524  1.00 81.17  ? 419  LYS A CA  1 
ATOM 3361 C C   . LYS A 1 419  ? 123.769 96.227  77.934  1.00 79.17  ? 419  LYS A C   1 
ATOM 3362 O O   . LYS A 1 419  ? 123.835 95.023  78.149  1.00 88.51  ? 419  LYS A O   1 
ATOM 3363 C CB  . LYS A 1 419  ? 125.236 97.566  76.427  1.00 88.77  ? 419  LYS A CB  1 
ATOM 3364 C CG  . LYS A 1 419  ? 126.450 96.907  77.064  1.00 99.14  ? 419  LYS A CG  1 
ATOM 3365 C CD  . LYS A 1 419  ? 127.686 97.775  77.024  1.00 118.50 ? 419  LYS A CD  1 
ATOM 3366 C CE  . LYS A 1 419  ? 128.021 98.286  75.636  1.00 133.52 ? 419  LYS A CE  1 
ATOM 3367 N NZ  . LYS A 1 419  ? 128.030 97.196  74.628  1.00 140.10 ? 419  LYS A NZ  1 
ATOM 3368 N N   . ALA A 1 420  ? 123.533 97.141  78.875  1.00 76.71  ? 420  ALA A N   1 
ATOM 3369 C CA  . ALA A 1 420  ? 123.405 96.768  80.269  1.00 82.96  ? 420  ALA A CA  1 
ATOM 3370 C C   . ALA A 1 420  ? 122.367 95.661  80.400  1.00 75.91  ? 420  ALA A C   1 
ATOM 3371 O O   . ALA A 1 420  ? 122.662 94.616  80.961  1.00 85.29  ? 420  ALA A O   1 
ATOM 3372 C CB  . ALA A 1 420  ? 123.063 97.967  81.126  1.00 92.34  ? 420  ALA A CB  1 
ATOM 3373 N N   . PHE A 1 421  ? 121.163 95.860  79.865  1.00 73.35  ? 421  PHE A N   1 
ATOM 3374 C CA  . PHE A 1 421  ? 120.120 94.878  80.107  1.00 78.89  ? 421  PHE A CA  1 
ATOM 3375 C C   . PHE A 1 421  ? 120.631 93.481  79.768  1.00 93.72  ? 421  PHE A C   1 
ATOM 3376 O O   . PHE A 1 421  ? 120.484 92.575  80.582  1.00 112.31 ? 421  PHE A O   1 
ATOM 3377 C CB  . PHE A 1 421  ? 118.823 95.184  79.358  1.00 80.10  ? 421  PHE A CB  1 
ATOM 3378 C CG  . PHE A 1 421  ? 117.843 96.030  80.125  1.00 84.63  ? 421  PHE A CG  1 
ATOM 3379 C CD1 . PHE A 1 421  ? 117.518 95.730  81.437  1.00 92.06  ? 421  PHE A CD1 1 
ATOM 3380 C CD2 . PHE A 1 421  ? 117.234 97.119  79.524  1.00 99.22  ? 421  PHE A CD2 1 
ATOM 3381 C CE1 . PHE A 1 421  ? 116.625 96.523  82.139  1.00 107.72 ? 421  PHE A CE1 1 
ATOM 3382 C CE2 . PHE A 1 421  ? 116.343 97.911  80.228  1.00 111.88 ? 421  PHE A CE2 1 
ATOM 3383 C CZ  . PHE A 1 421  ? 116.028 97.604  81.530  1.00 113.80 ? 421  PHE A CZ  1 
ATOM 3384 N N   . LYS A 1 422  ? 121.266 93.301  78.603  1.00 98.52  ? 422  LYS A N   1 
ATOM 3385 C CA  . LYS A 1 422  ? 121.603 91.949  78.173  1.00 100.26 ? 422  LYS A CA  1 
ATOM 3386 C C   . LYS A 1 422  ? 122.742 91.380  79.019  1.00 94.31  ? 422  LYS A C   1 
ATOM 3387 O O   . LYS A 1 422  ? 122.651 90.230  79.435  1.00 99.60  ? 422  LYS A O   1 
ATOM 3388 C CB  . LYS A 1 422  ? 121.862 91.815  76.667  1.00 106.47 ? 422  LYS A CB  1 
ATOM 3389 C CG  . LYS A 1 422  ? 122.393 93.029  75.913  1.00 117.68 ? 422  LYS A CG  1 
ATOM 3390 C CD  . LYS A 1 422  ? 122.322 92.841  74.407  1.00 127.88 ? 422  LYS A CD  1 
ATOM 3391 C CE  . LYS A 1 422  ? 120.902 92.661  73.908  1.00 130.09 ? 422  LYS A CE  1 
ATOM 3392 N NZ  . LYS A 1 422  ? 120.826 92.527  72.434  1.00 132.67 ? 422  LYS A NZ  1 
ATOM 3393 N N   . GLU A 1 423  ? 123.776 92.174  79.319  1.00 89.43  ? 423  GLU A N   1 
ATOM 3394 C CA  . GLU A 1 423  ? 124.913 91.653  80.063  1.00 95.29  ? 423  GLU A CA  1 
ATOM 3395 C C   . GLU A 1 423  ? 124.488 91.290  81.485  1.00 94.18  ? 423  GLU A C   1 
ATOM 3396 O O   . GLU A 1 423  ? 124.638 90.143  81.901  1.00 101.51 ? 423  GLU A O   1 
ATOM 3397 C CB  . GLU A 1 423  ? 126.072 92.651  80.096  1.00 107.90 ? 423  GLU A CB  1 
ATOM 3398 C CG  . GLU A 1 423  ? 127.433 91.986  80.046  1.00 131.70 ? 423  GLU A CG  1 
ATOM 3399 C CD  . GLU A 1 423  ? 127.814 91.475  78.666  1.00 159.32 ? 423  GLU A CD  1 
ATOM 3400 O OE1 . GLU A 1 423  ? 127.005 90.739  78.060  1.00 169.21 ? 423  GLU A OE1 1 
ATOM 3401 O OE2 . GLU A 1 423  ? 128.919 91.816  78.195  1.00 179.68 ? 423  GLU A OE2 1 
ATOM 3402 N N   . VAL A 1 424  ? 123.953 92.271  82.222  1.00 89.46  ? 424  VAL A N   1 
ATOM 3403 C CA  . VAL A 1 424  ? 123.762 92.130  83.656  1.00 83.52  ? 424  VAL A CA  1 
ATOM 3404 C C   . VAL A 1 424  ? 122.666 91.104  83.918  1.00 70.48  ? 424  VAL A C   1 
ATOM 3405 O O   . VAL A 1 424  ? 122.828 90.243  84.780  1.00 79.67  ? 424  VAL A O   1 
ATOM 3406 C CB  . VAL A 1 424  ? 123.459 93.473  84.351  1.00 89.26  ? 424  VAL A CB  1 
ATOM 3407 C CG1 . VAL A 1 424  ? 123.083 93.277  85.815  1.00 94.66  ? 424  VAL A CG1 1 
ATOM 3408 C CG2 . VAL A 1 424  ? 124.623 94.451  84.232  1.00 88.04  ? 424  VAL A CG2 1 
ATOM 3409 N N   . PHE A 1 425  ? 121.556 91.196  83.189  1.00 63.42  ? 425  PHE A N   1 
ATOM 3410 C CA  . PHE A 1 425  ? 120.481 90.244  83.391  1.00 75.84  ? 425  PHE A CA  1 
ATOM 3411 C C   . PHE A 1 425  ? 120.895 88.884  82.840  1.00 85.32  ? 425  PHE A C   1 
ATOM 3412 O O   . PHE A 1 425  ? 120.422 87.859  83.322  1.00 96.85  ? 425  PHE A O   1 
ATOM 3413 C CB  . PHE A 1 425  ? 119.174 90.737  82.769  1.00 85.99  ? 425  PHE A CB  1 
ATOM 3414 C CG  . PHE A 1 425  ? 118.539 91.921  83.455  1.00 93.71  ? 425  PHE A CG  1 
ATOM 3415 C CD1 . PHE A 1 425  ? 119.205 92.630  84.447  1.00 98.37  ? 425  PHE A CD1 1 
ATOM 3416 C CD2 . PHE A 1 425  ? 117.256 92.322  83.106  1.00 95.78  ? 425  PHE A CD2 1 
ATOM 3417 C CE1 . PHE A 1 425  ? 118.603 93.716  85.064  1.00 103.44 ? 425  PHE A CE1 1 
ATOM 3418 C CE2 . PHE A 1 425  ? 116.658 93.409  83.722  1.00 103.46 ? 425  PHE A CE2 1 
ATOM 3419 C CZ  . PHE A 1 425  ? 117.333 94.104  84.700  1.00 107.56 ? 425  PHE A CZ  1 
ATOM 3420 N N   . GLY A 1 426  ? 121.789 88.875  81.846  1.00 90.80  ? 426  GLY A N   1 
ATOM 3421 C CA  . GLY A 1 426  ? 122.315 87.629  81.315  1.00 98.70  ? 426  GLY A CA  1 
ATOM 3422 C C   . GLY A 1 426  ? 121.216 86.757  80.707  1.00 97.69  ? 426  GLY A C   1 
ATOM 3423 O O   . GLY A 1 426  ? 120.395 87.242  79.932  1.00 102.05 ? 426  GLY A O   1 
ATOM 3424 N N   . ASP A 1 427  ? 121.206 85.475  81.089  1.00 98.88  ? 427  ASP A N   1 
ATOM 3425 C CA  . ASP A 1 427  ? 120.357 84.469  80.472  1.00 108.53 ? 427  ASP A CA  1 
ATOM 3426 C C   . ASP A 1 427  ? 118.890 84.883  80.502  1.00 100.11 ? 427  ASP A C   1 
ATOM 3427 O O   . ASP A 1 427  ? 118.124 84.503  79.619  1.00 109.27 ? 427  ASP A O   1 
ATOM 3428 C CB  . ASP A 1 427  ? 120.491 83.123  81.189  1.00 131.24 ? 427  ASP A CB  1 
ATOM 3429 C CG  . ASP A 1 427  ? 119.651 82.004  80.592  1.00 148.88 ? 427  ASP A CG  1 
ATOM 3430 O OD1 . ASP A 1 427  ? 119.254 82.119  79.410  1.00 150.75 ? 427  ASP A OD1 1 
ATOM 3431 O OD2 . ASP A 1 427  ? 119.391 81.022  81.319  1.00 166.59 ? 427  ASP A OD2 1 
ATOM 3432 N N   . LEU A 1 428  ? 118.510 85.669  81.512  1.00 90.88  ? 428  LEU A N   1 
ATOM 3433 C CA  . LEU A 1 428  ? 117.115 85.830  81.885  1.00 93.61  ? 428  LEU A CA  1 
ATOM 3434 C C   . LEU A 1 428  ? 116.323 86.532  80.780  1.00 93.68  ? 428  LEU A C   1 
ATOM 3435 O O   . LEU A 1 428  ? 115.249 86.069  80.403  1.00 89.71  ? 428  LEU A O   1 
ATOM 3436 C CB  . LEU A 1 428  ? 117.068 86.610  83.201  1.00 102.03 ? 428  LEU A CB  1 
ATOM 3437 C CG  . LEU A 1 428  ? 117.928 86.036  84.330  1.00 113.49 ? 428  LEU A CG  1 
ATOM 3438 C CD1 . LEU A 1 428  ? 117.730 86.802  85.631  1.00 117.16 ? 428  LEU A CD1 1 
ATOM 3439 C CD2 . LEU A 1 428  ? 117.648 84.554  84.531  1.00 118.89 ? 428  LEU A CD2 1 
ATOM 3440 N N   . LEU A 1 429  ? 116.856 87.640  80.249  1.00 84.72  ? 429  LEU A N   1 
ATOM 3441 C CA  . LEU A 1 429  ? 116.130 88.464  79.290  1.00 73.51  ? 429  LEU A CA  1 
ATOM 3442 C C   . LEU A 1 429  ? 115.583 87.600  78.158  1.00 62.29  ? 429  LEU A C   1 
ATOM 3443 O O   . LEU A 1 429  ? 116.317 86.810  77.576  1.00 70.91  ? 429  LEU A O   1 
ATOM 3444 C CB  . LEU A 1 429  ? 117.084 89.541  78.765  1.00 79.81  ? 429  LEU A CB  1 
ATOM 3445 C CG  . LEU A 1 429  ? 116.512 90.955  78.743  1.00 99.21  ? 429  LEU A CG  1 
ATOM 3446 C CD1 . LEU A 1 429  ? 115.795 91.265  80.054  1.00 111.74 ? 429  LEU A CD1 1 
ATOM 3447 C CD2 . LEU A 1 429  ? 117.616 91.968  78.490  1.00 101.92 ? 429  LEU A CD2 1 
ATOM 3448 N N   . LEU A 1 430  ? 114.291 87.748  77.860  1.00 58.72  ? 430  LEU A N   1 
ATOM 3449 C CA  . LEU A 1 430  ? 113.612 86.873  76.921  1.00 64.64  ? 430  LEU A CA  1 
ATOM 3450 C C   . LEU A 1 430  ? 113.844 87.368  75.496  1.00 77.00  ? 430  LEU A C   1 
ATOM 3451 O O   . LEU A 1 430  ? 112.950 87.928  74.866  1.00 82.44  ? 430  LEU A O   1 
ATOM 3452 C CB  . LEU A 1 430  ? 112.123 86.864  77.260  1.00 67.49  ? 430  LEU A CB  1 
ATOM 3453 C CG  . LEU A 1 430  ? 111.282 85.877  76.460  1.00 79.14  ? 430  LEU A CG  1 
ATOM 3454 C CD1 . LEU A 1 430  ? 111.374 84.482  77.058  1.00 94.12  ? 430  LEU A CD1 1 
ATOM 3455 C CD2 . LEU A 1 430  ? 109.842 86.338  76.396  1.00 82.01  ? 430  LEU A CD2 1 
ATOM 3456 N N   . THR A 1 431  ? 115.053 87.135  74.982  1.00 86.95  ? 431  THR A N   1 
ATOM 3457 C CA  . THR A 1 431  ? 115.468 87.697  73.707  1.00 90.31  ? 431  THR A CA  1 
ATOM 3458 C C   . THR A 1 431  ? 114.710 87.041  72.555  1.00 88.24  ? 431  THR A C   1 
ATOM 3459 O O   . THR A 1 431  ? 114.387 87.718  71.585  1.00 99.32  ? 431  THR A O   1 
ATOM 3460 C CB  . THR A 1 431  ? 116.988 87.592  73.518  1.00 100.75 ? 431  THR A CB  1 
ATOM 3461 O OG1 . THR A 1 431  ? 117.425 86.346  74.063  1.00 107.18 ? 431  THR A OG1 1 
ATOM 3462 C CG2 . THR A 1 431  ? 117.739 88.730  74.176  1.00 103.38 ? 431  THR A CG2 1 
ATOM 3463 N N   . LYS A 1 432  ? 114.432 85.736  72.656  1.00 85.49  ? 432  LYS A N   1 
ATOM 3464 C CA  . LYS A 1 432  ? 113.839 85.003  71.547  1.00 90.89  ? 432  LYS A CA  1 
ATOM 3465 C C   . LYS A 1 432  ? 112.467 84.466  71.942  1.00 81.72  ? 432  LYS A C   1 
ATOM 3466 O O   . LYS A 1 432  ? 112.318 83.848  72.992  1.00 90.83  ? 432  LYS A O   1 
ATOM 3467 C CB  . LYS A 1 432  ? 114.760 83.855  71.121  1.00 117.47 ? 432  LYS A CB  1 
ATOM 3468 C CG  . LYS A 1 432  ? 116.203 84.261  70.845  1.00 143.88 ? 432  LYS A CG  1 
ATOM 3469 C CD  . LYS A 1 432  ? 117.022 83.227  70.090  1.00 167.38 ? 432  LYS A CD  1 
ATOM 3470 C CE  . LYS A 1 432  ? 116.936 83.355  68.581  1.00 179.83 ? 432  LYS A CE  1 
ATOM 3471 N NZ  . LYS A 1 432  ? 115.590 83.023  68.054  1.00 184.82 ? 432  LYS A NZ  1 
ATOM 3472 N N   . PRO A 1 433  ? 111.425 84.636  71.102  1.00 80.43  ? 433  PRO A N   1 
ATOM 3473 C CA  . PRO A 1 433  ? 110.096 84.136  71.437  1.00 84.80  ? 433  PRO A CA  1 
ATOM 3474 C C   . PRO A 1 433  ? 110.218 82.639  71.680  1.00 93.01  ? 433  PRO A C   1 
ATOM 3475 O O   . PRO A 1 433  ? 110.871 81.941  70.910  1.00 98.65  ? 433  PRO A O   1 
ATOM 3476 C CB  . PRO A 1 433  ? 109.203 84.438  70.226  1.00 88.10  ? 433  PRO A CB  1 
ATOM 3477 C CG  . PRO A 1 433  ? 110.025 85.369  69.343  1.00 94.29  ? 433  PRO A CG  1 
ATOM 3478 C CD  . PRO A 1 433  ? 111.476 85.252  69.773  1.00 88.35  ? 433  PRO A CD  1 
ATOM 3479 N N   . THR A 1 434  ? 109.613 82.174  72.774  1.00 106.43 ? 434  THR A N   1 
ATOM 3480 C CA  . THR A 1 434  ? 109.810 80.819  73.259  1.00 124.38 ? 434  THR A CA  1 
ATOM 3481 C C   . THR A 1 434  ? 109.145 79.788  72.352  1.00 133.44 ? 434  THR A C   1 
ATOM 3482 O O   . THR A 1 434  ? 109.723 78.738  72.087  1.00 143.49 ? 434  THR A O   1 
ATOM 3483 C CB  . THR A 1 434  ? 109.216 80.640  74.659  1.00 133.32 ? 434  THR A CB  1 
ATOM 3484 O OG1 . THR A 1 434  ? 107.828 80.921  74.500  1.00 133.73 ? 434  THR A OG1 1 
ATOM 3485 C CG2 . THR A 1 434  ? 109.841 81.538  75.705  1.00 135.17 ? 434  THR A CG2 1 
ATOM 3486 N N   . GLU A 1 435  ? 107.908 80.058  71.920  1.00 147.70 ? 435  GLU A N   1 
ATOM 3487 C CA  . GLU A 1 435  ? 107.124 79.040  71.238  1.00 175.20 ? 435  GLU A CA  1 
ATOM 3488 C C   . GLU A 1 435  ? 107.065 79.298  69.734  1.00 199.43 ? 435  GLU A C   1 
ATOM 3489 O O   . GLU A 1 435  ? 106.029 79.058  69.117  1.00 214.35 ? 435  GLU A O   1 
ATOM 3490 C CB  . GLU A 1 435  ? 105.703 78.987  71.805  1.00 187.12 ? 435  GLU A CB  1 
ATOM 3491 C CG  . GLU A 1 435  ? 105.643 78.615  73.271  1.00 202.19 ? 435  GLU A CG  1 
ATOM 3492 C CD  . GLU A 1 435  ? 106.310 77.297  73.626  1.00 214.78 ? 435  GLU A CD  1 
ATOM 3493 O OE1 . GLU A 1 435  ? 107.263 77.318  74.433  1.00 219.79 ? 435  GLU A OE1 1 
ATOM 3494 O OE2 . GLU A 1 435  ? 105.868 76.252  73.107  1.00 223.13 ? 435  GLU A OE2 1 
ATOM 3495 N N   . ALA A 1 436  ? 108.178 79.749  69.139  1.00 211.69 ? 436  ALA A N   1 
ATOM 3496 C CA  . ALA A 1 436  ? 108.241 79.983  67.704  1.00 222.37 ? 436  ALA A CA  1 
ATOM 3497 C C   . ALA A 1 436  ? 107.094 80.908  67.289  1.00 234.83 ? 436  ALA A C   1 
ATOM 3498 O O   . ALA A 1 436  ? 106.939 81.972  67.883  1.00 239.65 ? 436  ALA A O   1 
ATOM 3499 C CB  . ALA A 1 436  ? 108.230 78.658  66.978  1.00 224.94 ? 436  ALA A CB  1 
ATOM 3500 N N   . SER A 1 437  ? 106.285 80.501  66.297  1.00 238.10 ? 437  SER A N   1 
ATOM 3501 C CA  . SER A 1 437  ? 105.197 81.325  65.792  1.00 239.30 ? 437  SER A CA  1 
ATOM 3502 C C   . SER A 1 437  ? 104.214 81.687  66.906  1.00 224.36 ? 437  SER A C   1 
ATOM 3503 O O   . SER A 1 437  ? 103.835 82.848  67.020  1.00 231.66 ? 437  SER A O   1 
ATOM 3504 C CB  . SER A 1 437  ? 104.495 80.646  64.645  1.00 247.64 ? 437  SER A CB  1 
ATOM 3505 O OG  . SER A 1 437  ? 103.937 79.408  65.056  1.00 244.85 ? 437  SER A OG  1 
ATOM 3506 N N   . ALA A 1 438  ? 103.788 80.687  67.694  1.00 200.01 ? 438  ALA A N   1 
ATOM 3507 C CA  . ALA A 1 438  ? 102.949 80.881  68.873  1.00 186.27 ? 438  ALA A CA  1 
ATOM 3508 C C   . ALA A 1 438  ? 101.629 81.585  68.539  1.00 170.96 ? 438  ALA A C   1 
ATOM 3509 O O   . ALA A 1 438  ? 101.600 82.791  68.313  1.00 175.62 ? 438  ALA A O   1 
ATOM 3510 C CB  . ALA A 1 438  ? 103.720 81.654  69.916  1.00 192.43 ? 438  ALA A CB  1 
ATOM 3511 N N   . ASP A 1 439  ? 100.515 80.844  68.573  1.00 158.21 ? 439  ASP A N   1 
ATOM 3512 C CA  . ASP A 1 439  ? 99.205  81.438  68.346  1.00 152.30 ? 439  ASP A CA  1 
ATOM 3513 C C   . ASP A 1 439  ? 98.858  82.418  69.473  1.00 132.58 ? 439  ASP A C   1 
ATOM 3514 O O   . ASP A 1 439  ? 98.308  83.482  69.206  1.00 122.92 ? 439  ASP A O   1 
ATOM 3515 C CB  . ASP A 1 439  ? 98.125  80.365  68.168  1.00 161.93 ? 439  ASP A CB  1 
ATOM 3516 C CG  . ASP A 1 439  ? 97.993  79.418  69.348  1.00 173.21 ? 439  ASP A CG  1 
ATOM 3517 O OD1 . ASP A 1 439  ? 98.991  78.743  69.667  1.00 177.92 ? 439  ASP A OD1 1 
ATOM 3518 O OD2 . ASP A 1 439  ? 96.897  79.373  69.944  1.00 180.84 ? 439  ASP A OD2 1 
ATOM 3519 N N   . GLN A 1 440  ? 99.193  82.060  70.721  1.00 116.02 ? 440  GLN A N   1 
ATOM 3520 C CA  . GLN A 1 440  ? 98.848  82.849  71.897  1.00 93.50  ? 440  GLN A CA  1 
ATOM 3521 C C   . GLN A 1 440  ? 100.085 83.021  72.769  1.00 81.75  ? 440  GLN A C   1 
ATOM 3522 O O   . GLN A 1 440  ? 101.067 82.306  72.596  1.00 88.94  ? 440  GLN A O   1 
ATOM 3523 C CB  . GLN A 1 440  ? 97.735  82.163  72.689  1.00 93.41  ? 440  GLN A CB  1 
ATOM 3524 C CG  . GLN A 1 440  ? 98.097  80.767  73.180  1.00 100.96 ? 440  GLN A CG  1 
ATOM 3525 C CD  . GLN A 1 440  ? 96.952  80.107  73.910  1.00 122.49 ? 440  GLN A CD  1 
ATOM 3526 O OE1 . GLN A 1 440  ? 95.885  80.690  74.093  1.00 132.79 ? 440  GLN A OE1 1 
ATOM 3527 N NE2 . GLN A 1 440  ? 97.170  78.877  74.348  1.00 130.91 ? 440  GLN A NE2 1 
ATOM 3528 N N   . LEU A 1 441  ? 100.024 83.962  73.719  1.00 76.41  ? 441  LEU A N   1 
ATOM 3529 C CA  . LEU A 1 441  ? 101.179 84.302  74.537  1.00 70.12  ? 441  LEU A CA  1 
ATOM 3530 C C   . LEU A 1 441  ? 101.664 83.078  75.303  1.00 65.05  ? 441  LEU A C   1 
ATOM 3531 O O   . LEU A 1 441  ? 100.873 82.246  75.729  1.00 64.92  ? 441  LEU A O   1 
ATOM 3532 C CB  . LEU A 1 441  ? 100.836 85.446  75.495  1.00 69.94  ? 441  LEU A CB  1 
ATOM 3533 C CG  . LEU A 1 441  ? 101.471 86.793  75.148  1.00 74.61  ? 441  LEU A CG  1 
ATOM 3534 C CD1 . LEU A 1 441  ? 100.662 87.942  75.741  1.00 82.42  ? 441  LEU A CD1 1 
ATOM 3535 C CD2 . LEU A 1 441  ? 102.919 86.861  75.620  1.00 72.46  ? 441  LEU A CD2 1 
ATOM 3536 N N   . PRO A 1 442  ? 102.990 82.933  75.494  1.00 62.46  ? 442  PRO A N   1 
ATOM 3537 C CA  . PRO A 1 442  ? 103.533 81.841  76.297  1.00 64.05  ? 442  PRO A CA  1 
ATOM 3538 C C   . PRO A 1 442  ? 103.009 81.910  77.727  1.00 80.08  ? 442  PRO A C   1 
ATOM 3539 O O   . PRO A 1 442  ? 102.849 82.992  78.284  1.00 84.12  ? 442  PRO A O   1 
ATOM 3540 C CB  . PRO A 1 442  ? 105.040 82.095  76.227  1.00 62.03  ? 442  PRO A CB  1 
ATOM 3541 C CG  . PRO A 1 442  ? 105.114 83.589  76.039  1.00 65.38  ? 442  PRO A CG  1 
ATOM 3542 C CD  . PRO A 1 442  ? 104.041 83.831  75.000  1.00 63.19  ? 442  PRO A CD  1 
ATOM 3543 N N   . SER A 1 443  ? 102.723 80.730  78.287  1.00 97.47  ? 443  SER A N   1 
ATOM 3544 C CA  . SER A 1 443  ? 102.241 80.549  79.648  1.00 97.68  ? 443  SER A CA  1 
ATOM 3545 C C   . SER A 1 443  ? 103.329 80.856  80.678  1.00 95.17  ? 443  SER A C   1 
ATOM 3546 O O   . SER A 1 443  ? 104.499 80.632  80.410  1.00 104.13 ? 443  SER A O   1 
ATOM 3547 C CB  . SER A 1 443  ? 101.745 79.142  79.802  1.00 98.15  ? 443  SER A CB  1 
ATOM 3548 O OG  . SER A 1 443  ? 101.994 78.673  81.112  1.00 94.54  ? 443  SER A OG  1 
ATOM 3549 N N   . PRO A 1 444  ? 103.006 81.334  81.901  1.00 79.79  ? 444  PRO A N   1 
ATOM 3550 C CA  . PRO A 1 444  ? 104.040 81.721  82.859  1.00 72.87  ? 444  PRO A CA  1 
ATOM 3551 C C   . PRO A 1 444  ? 105.116 80.668  83.075  1.00 81.25  ? 444  PRO A C   1 
ATOM 3552 O O   . PRO A 1 444  ? 106.286 81.013  83.214  1.00 78.21  ? 444  PRO A O   1 
ATOM 3553 C CB  . PRO A 1 444  ? 103.259 81.898  84.160  1.00 77.33  ? 444  PRO A CB  1 
ATOM 3554 C CG  . PRO A 1 444  ? 101.889 82.318  83.705  1.00 78.66  ? 444  PRO A CG  1 
ATOM 3555 C CD  . PRO A 1 444  ? 101.652 81.520  82.441  1.00 79.76  ? 444  PRO A CD  1 
ATOM 3556 N N   . SER A 1 445  ? 104.708 79.392  83.100  1.00 92.65  ? 445  SER A N   1 
ATOM 3557 C CA  . SER A 1 445  ? 105.623 78.294  83.373  1.00 100.97 ? 445  SER A CA  1 
ATOM 3558 C C   . SER A 1 445  ? 106.747 78.259  82.339  1.00 97.69  ? 445  SER A C   1 
ATOM 3559 O O   . SER A 1 445  ? 107.907 78.063  82.695  1.00 97.24  ? 445  SER A O   1 
ATOM 3560 C CB  . SER A 1 445  ? 104.887 76.975  83.426  1.00 102.79 ? 445  SER A CB  1 
ATOM 3561 O OG  . SER A 1 445  ? 103.883 76.995  84.428  1.00 99.99  ? 445  SER A OG  1 
ATOM 3562 N N   . GLN A 1 446  ? 106.392 78.462  81.064  1.00 87.45  ? 446  GLN A N   1 
ATOM 3563 C CA  . GLN A 1 446  ? 107.350 78.413  79.974  1.00 81.36  ? 446  GLN A CA  1 
ATOM 3564 C C   . GLN A 1 446  ? 108.413 79.491  80.177  1.00 77.17  ? 446  GLN A C   1 
ATOM 3565 O O   . GLN A 1 446  ? 109.589 79.244  79.913  1.00 87.39  ? 446  GLN A O   1 
ATOM 3566 C CB  . GLN A 1 446  ? 106.656 78.595  78.621  1.00 85.58  ? 446  GLN A CB  1 
ATOM 3567 C CG  . GLN A 1 446  ? 105.492 77.644  78.349  1.00 91.22  ? 446  GLN A CG  1 
ATOM 3568 C CD  . GLN A 1 446  ? 105.871 76.191  78.229  1.00 107.95 ? 446  GLN A CD  1 
ATOM 3569 O OE1 . GLN A 1 446  ? 105.680 75.565  77.188  1.00 115.29 ? 446  GLN A OE1 1 
ATOM 3570 N NE2 . GLN A 1 446  ? 106.380 75.633  79.316  1.00 117.03 ? 446  GLN A NE2 1 
ATOM 3571 N N   . LEU A 1 447  ? 107.996 80.673  80.656  1.00 70.20  ? 447  LEU A N   1 
ATOM 3572 C CA  . LEU A 1 447  ? 108.894 81.812  80.790  1.00 73.98  ? 447  LEU A CA  1 
ATOM 3573 C C   . LEU A 1 447  ? 109.474 81.886  82.198  1.00 72.44  ? 447  LEU A C   1 
ATOM 3574 O O   . LEU A 1 447  ? 110.111 82.881  82.527  1.00 67.38  ? 447  LEU A O   1 
ATOM 3575 C CB  . LEU A 1 447  ? 108.169 83.132  80.502  1.00 80.64  ? 447  LEU A CB  1 
ATOM 3576 C CG  . LEU A 1 447  ? 107.492 83.270  79.139  1.00 86.08  ? 447  LEU A CG  1 
ATOM 3577 C CD1 . LEU A 1 447  ? 106.177 82.521  79.144  1.00 85.21  ? 447  LEU A CD1 1 
ATOM 3578 C CD2 . LEU A 1 447  ? 107.273 84.739  78.783  1.00 88.76  ? 447  LEU A CD2 1 
ATOM 3579 N N   . ARG A 1 448  ? 109.249 80.865  83.033  1.00 73.31  ? 448  ARG A N   1 
ATOM 3580 C CA  . ARG A 1 448  ? 109.679 80.911  84.423  1.00 76.94  ? 448  ARG A CA  1 
ATOM 3581 C C   . ARG A 1 448  ? 111.163 81.257  84.507  1.00 68.29  ? 448  ARG A C   1 
ATOM 3582 O O   . ARG A 1 448  ? 111.959 80.667  83.787  1.00 73.75  ? 448  ARG A O   1 
ATOM 3583 C CB  . ARG A 1 448  ? 109.441 79.558  85.091  1.00 84.66  ? 448  ARG A CB  1 
ATOM 3584 C CG  . ARG A 1 448  ? 109.839 79.507  86.560  1.00 96.44  ? 448  ARG A CG  1 
ATOM 3585 C CD  . ARG A 1 448  ? 109.628 78.115  87.135  1.00 105.15 ? 448  ARG A CD  1 
ATOM 3586 N NE  . ARG A 1 448  ? 108.241 77.682  86.984  1.00 120.18 ? 448  ARG A NE  1 
ATOM 3587 C CZ  . ARG A 1 448  ? 107.767 76.491  87.341  1.00 131.67 ? 448  ARG A CZ  1 
ATOM 3588 N NH1 . ARG A 1 448  ? 106.492 76.204  87.141  1.00 134.99 ? 448  ARG A NH1 1 
ATOM 3589 N NH2 . ARG A 1 448  ? 108.565 75.596  87.898  1.00 137.10 ? 448  ARG A NH2 1 
ATOM 3590 N N   . GLU A 1 449  ? 111.502 82.175  85.421  1.00 65.14  ? 449  GLU A N   1 
ATOM 3591 C CA  . GLU A 1 449  ? 112.849 82.678  85.620  1.00 72.64  ? 449  GLU A CA  1 
ATOM 3592 C C   . GLU A 1 449  ? 113.257 83.676  84.534  1.00 73.19  ? 449  GLU A C   1 
ATOM 3593 O O   . GLU A 1 449  ? 114.444 83.982  84.431  1.00 75.83  ? 449  GLU A O   1 
ATOM 3594 C CB  . GLU A 1 449  ? 113.877 81.543  85.670  1.00 96.56  ? 449  GLU A CB  1 
ATOM 3595 C CG  . GLU A 1 449  ? 113.643 80.514  86.767  1.00 125.51 ? 449  GLU A CG  1 
ATOM 3596 C CD  . GLU A 1 449  ? 113.790 81.034  88.186  1.00 152.06 ? 449  GLU A CD  1 
ATOM 3597 O OE1 . GLU A 1 449  ? 113.596 80.242  89.136  1.00 165.73 ? 449  GLU A OE1 1 
ATOM 3598 O OE2 . GLU A 1 449  ? 114.113 82.222  88.336  1.00 161.04 ? 449  GLU A OE2 1 
ATOM 3599 N N   . LYS A 1 450  ? 112.305 84.226  83.756  1.00 72.59  ? 450  LYS A N   1 
ATOM 3600 C CA  . LYS A 1 450  ? 112.659 85.097  82.635  1.00 77.07  ? 450  LYS A CA  1 
ATOM 3601 C C   . LYS A 1 450  ? 112.053 86.497  82.757  1.00 65.34  ? 450  LYS A C   1 
ATOM 3602 O O   . LYS A 1 450  ? 110.844 86.629  82.906  1.00 69.04  ? 450  LYS A O   1 
ATOM 3603 C CB  . LYS A 1 450  ? 112.194 84.505  81.300  1.00 93.25  ? 450  LYS A CB  1 
ATOM 3604 C CG  . LYS A 1 450  ? 112.787 83.150  80.934  1.00 113.26 ? 450  LYS A CG  1 
ATOM 3605 C CD  . LYS A 1 450  ? 114.298 83.147  80.789  1.00 127.32 ? 450  LYS A CD  1 
ATOM 3606 C CE  . LYS A 1 450  ? 114.851 81.821  80.308  1.00 136.69 ? 450  LYS A CE  1 
ATOM 3607 N NZ  . LYS A 1 450  ? 114.318 81.448  78.975  1.00 139.21 ? 450  LYS A NZ  1 
ATOM 3608 N N   . ILE A 1 451  ? 112.900 87.531  82.602  1.00 52.88  ? 451  ILE A N   1 
ATOM 3609 C CA  . ILE A 1 451  ? 112.482 88.925  82.500  1.00 47.76  ? 451  ILE A CA  1 
ATOM 3610 C C   . ILE A 1 451  ? 111.924 89.193  81.100  1.00 50.34  ? 451  ILE A C   1 
ATOM 3611 O O   . ILE A 1 451  ? 112.498 88.713  80.126  1.00 61.63  ? 451  ILE A O   1 
ATOM 3612 C CB  . ILE A 1 451  ? 113.675 89.855  82.790  1.00 44.18  ? 451  ILE A CB  1 
ATOM 3613 C CG1 . ILE A 1 451  ? 114.263 89.574  84.172  1.00 46.42  ? 451  ILE A CG1 1 
ATOM 3614 C CG2 . ILE A 1 451  ? 113.278 91.315  82.625  1.00 46.17  ? 451  ILE A CG2 1 
ATOM 3615 C CD1 . ILE A 1 451  ? 115.433 90.442  84.545  1.00 47.15  ? 451  ILE A CD1 1 
ATOM 3616 N N   . ILE A 1 452  ? 110.825 89.963  81.011  1.00 46.06  ? 452  ILE A N   1 
ATOM 3617 C CA  . ILE A 1 452  ? 110.256 90.430  79.750  1.00 46.29  ? 452  ILE A CA  1 
ATOM 3618 C C   . ILE A 1 452  ? 110.327 91.955  79.745  1.00 53.22  ? 452  ILE A C   1 
ATOM 3619 O O   . ILE A 1 452  ? 110.065 92.536  80.790  1.00 61.81  ? 452  ILE A O   1 
ATOM 3620 C CB  . ILE A 1 452  ? 108.797 89.959  79.601  1.00 42.60  ? 452  ILE A CB  1 
ATOM 3621 C CG1 . ILE A 1 452  ? 108.659 88.453  79.804  1.00 49.38  ? 452  ILE A CG1 1 
ATOM 3622 C CG2 . ILE A 1 452  ? 108.224 90.394  78.268  1.00 42.16  ? 452  ILE A CG2 1 
ATOM 3623 C CD1 . ILE A 1 452  ? 107.222 87.980  79.825  1.00 59.05  ? 452  ILE A CD1 1 
ATOM 3624 N N   . ILE A 1 453  ? 110.664 92.594  78.607  1.00 51.82  ? 453  ILE A N   1 
ATOM 3625 C CA  . ILE A 1 453  ? 110.796 94.048  78.553  1.00 50.52  ? 453  ILE A CA  1 
ATOM 3626 C C   . ILE A 1 453  ? 109.759 94.625  77.595  1.00 57.03  ? 453  ILE A C   1 
ATOM 3627 O O   . ILE A 1 453  ? 109.624 94.120  76.484  1.00 61.88  ? 453  ILE A O   1 
ATOM 3628 C CB  . ILE A 1 453  ? 112.219 94.469  78.140  1.00 51.25  ? 453  ILE A CB  1 
ATOM 3629 C CG1 . ILE A 1 453  ? 113.277 93.884  79.080  1.00 59.29  ? 453  ILE A CG1 1 
ATOM 3630 C CG2 . ILE A 1 453  ? 112.336 95.987  78.057  1.00 52.61  ? 453  ILE A CG2 1 
ATOM 3631 C CD1 . ILE A 1 453  ? 114.692 94.354  78.799  1.00 64.29  ? 453  ILE A CD1 1 
ATOM 3632 N N   . LYS A 1 454  ? 109.070 95.709  78.008  1.00 64.70  ? 454  LYS A N   1 
ATOM 3633 C CA  . LYS A 1 454  ? 108.119 96.397  77.138  1.00 69.07  ? 454  LYS A CA  1 
ATOM 3634 C C   . LYS A 1 454  ? 108.481 97.878  76.953  1.00 70.50  ? 454  LYS A C   1 
ATOM 3635 O O   . LYS A 1 454  ? 108.166 98.709  77.797  1.00 72.06  ? 454  LYS A O   1 
ATOM 3636 C CB  . LYS A 1 454  ? 106.683 96.228  77.644  1.00 66.84  ? 454  LYS A CB  1 
ATOM 3637 C CG  . LYS A 1 454  ? 106.399 96.653  79.075  1.00 73.89  ? 454  LYS A CG  1 
ATOM 3638 C CD  . LYS A 1 454  ? 104.932 96.510  79.444  1.00 76.57  ? 454  LYS A CD  1 
ATOM 3639 C CE  . LYS A 1 454  ? 103.999 97.353  78.596  1.00 71.68  ? 454  LYS A CE  1 
ATOM 3640 N NZ  . LYS A 1 454  ? 104.304 98.800  78.703  1.00 70.23  ? 454  LYS A NZ  1 
ATOM 3641 N N   . HIS A 1 455  ? 109.120 98.182  75.810  1.00 71.91  ? 455  HIS A N   1 
ATOM 3642 C CA  . HIS A 1 455  ? 109.428 99.528  75.338  1.00 70.40  ? 455  HIS A CA  1 
ATOM 3643 C C   . HIS A 1 455  ? 108.777 99.669  73.967  1.00 81.70  ? 455  HIS A C   1 
ATOM 3644 O O   . HIS A 1 455  ? 108.426 98.659  73.366  1.00 90.80  ? 455  HIS A O   1 
ATOM 3645 C CB  . HIS A 1 455  ? 110.941 99.689  75.164  1.00 67.77  ? 455  HIS A CB  1 
ATOM 3646 C CG  . HIS A 1 455  ? 111.429 101.090 75.075  1.00 81.18  ? 455  HIS A CG  1 
ATOM 3647 N ND1 . HIS A 1 455  ? 112.762 101.382 74.888  1.00 101.07 ? 455  HIS A ND1 1 
ATOM 3648 C CD2 . HIS A 1 455  ? 110.809 102.268 75.175  1.00 96.87  ? 455  HIS A CD2 1 
ATOM 3649 C CE1 . HIS A 1 455  ? 112.932 102.698 74.878  1.00 113.72 ? 455  HIS A CE1 1 
ATOM 3650 N NE2 . HIS A 1 455  ? 111.756 103.257 75.055  1.00 113.97 ? 455  HIS A NE2 1 
ATOM 3651 N N   . LYS A 1 456  ? 108.605 100.896 73.466  1.00 97.21  ? 456  LYS A N   1 
ATOM 3652 C CA  . LYS A 1 456  ? 107.977 101.101 72.169  1.00 119.43 ? 456  LYS A CA  1 
ATOM 3653 C C   . LYS A 1 456  ? 108.796 100.417 71.077  1.00 122.44 ? 456  LYS A C   1 
ATOM 3654 O O   . LYS A 1 456  ? 109.992 100.662 70.951  1.00 123.78 ? 456  LYS A O   1 
ATOM 3655 C CB  . LYS A 1 456  ? 107.820 102.596 71.874  1.00 139.46 ? 456  LYS A CB  1 
ATOM 3656 C CG  . LYS A 1 456  ? 106.687 103.286 72.624  1.00 153.26 ? 456  LYS A CG  1 
ATOM 3657 C CD  . LYS A 1 456  ? 106.493 104.740 72.223  1.00 158.72 ? 456  LYS A CD  1 
ATOM 3658 C CE  . LYS A 1 456  ? 107.690 105.617 72.529  1.00 163.24 ? 456  LYS A CE  1 
ATOM 3659 N NZ  . LYS A 1 456  ? 107.438 107.034 72.179  1.00 166.15 ? 456  LYS A NZ  1 
ATOM 3660 N N   . LYS A 1 457  ? 108.122 99.571  70.285  1.00 111.69 ? 457  LYS A N   1 
ATOM 3661 C CA  . LYS A 1 457  ? 108.764 98.796  69.238  1.00 103.36 ? 457  LYS A CA  1 
ATOM 3662 C C   . LYS A 1 457  ? 108.848 99.639  67.968  1.00 109.02 ? 457  LYS A C   1 
ATOM 3663 O O   . LYS A 1 457  ? 107.858 100.253 67.580  1.00 125.46 ? 457  LYS A O   1 
ATOM 3664 C CB  . LYS A 1 457  ? 107.969 97.513  68.976  1.00 107.15 ? 457  LYS A CB  1 
ATOM 3665 C CG  . LYS A 1 457  ? 108.588 96.593  67.936  1.00 124.00 ? 457  LYS A CG  1 
ATOM 3666 C CD  . LYS A 1 457  ? 109.937 96.050  68.347  1.00 141.12 ? 457  LYS A CD  1 
ATOM 3667 C CE  . LYS A 1 457  ? 110.544 95.123  67.314  1.00 159.88 ? 457  LYS A CE  1 
ATOM 3668 N NZ  . LYS A 1 457  ? 110.733 95.795  66.005  1.00 169.44 ? 457  LYS A NZ  1 
ATOM 3669 N N   . LEU A 1 458  ? 110.019 99.653  67.313  1.00 105.21 ? 458  LEU A N   1 
ATOM 3670 C CA  . LEU A 1 458  ? 110.192 100.386 66.067  1.00 98.83  ? 458  LEU A CA  1 
ATOM 3671 C C   . LEU A 1 458  ? 109.300 99.779  64.988  1.00 106.11 ? 458  LEU A C   1 
ATOM 3672 O O   . LEU A 1 458  ? 109.199 98.559  64.887  1.00 101.74 ? 458  LEU A O   1 
ATOM 3673 C CB  . LEU A 1 458  ? 111.663 100.341 65.641  1.00 93.66  ? 458  LEU A CB  1 
ATOM 3674 C CG  . LEU A 1 458  ? 112.646 101.033 66.585  1.00 102.96 ? 458  LEU A CG  1 
ATOM 3675 C CD1 . LEU A 1 458  ? 114.017 101.184 65.937  1.00 105.26 ? 458  LEU A CD1 1 
ATOM 3676 C CD2 . LEU A 1 458  ? 112.122 102.391 67.034  1.00 109.22 ? 458  LEU A CD2 1 
ATOM 3677 N N   . GLY A 1 459  ? 108.653 100.652 64.201  1.00 126.63 ? 459  GLY A N   1 
ATOM 3678 C CA  . GLY A 1 459  ? 107.867 100.252 63.039  1.00 137.75 ? 459  GLY A CA  1 
ATOM 3679 C C   . GLY A 1 459  ? 108.036 101.212 61.867  1.00 132.35 ? 459  GLY A C   1 
ATOM 3680 O O   . GLY A 1 459  ? 108.719 100.820 60.890  1.00 108.44 ? 459  GLY A O   1 
ATOM 3681 N N   . HIS A 1 475  ? 105.584 119.790 80.743  1.00 131.11 ? 475  HIS A N   1 
ATOM 3682 C CA  . HIS A 1 475  ? 106.596 120.489 81.586  1.00 140.56 ? 475  HIS A CA  1 
ATOM 3683 C C   . HIS A 1 475  ? 105.875 121.129 82.779  1.00 137.43 ? 475  HIS A C   1 
ATOM 3684 O O   . HIS A 1 475  ? 105.682 120.458 83.792  1.00 141.62 ? 475  HIS A O   1 
ATOM 3685 C CB  . HIS A 1 475  ? 107.455 121.393 80.689  1.00 150.13 ? 475  HIS A CB  1 
ATOM 3686 C CG  . HIS A 1 475  ? 108.806 121.745 81.224  1.00 163.26 ? 475  HIS A CG  1 
ATOM 3687 N ND1 . HIS A 1 475  ? 109.393 121.166 82.330  1.00 169.88 ? 475  HIS A ND1 1 
ATOM 3688 C CD2 . HIS A 1 475  ? 109.698 122.629 80.756  1.00 175.44 ? 475  HIS A CD2 1 
ATOM 3689 C CE1 . HIS A 1 475  ? 110.592 121.701 82.520  1.00 179.08 ? 475  HIS A CE1 1 
ATOM 3690 N NE2 . HIS A 1 475  ? 110.796 122.593 81.576  1.00 180.94 ? 475  HIS A NE2 1 
ATOM 3691 N N   . LYS A 1 476  ? 105.484 122.411 82.657  1.00 125.61 ? 476  LYS A N   1 
ATOM 3692 C CA  . LYS A 1 476  ? 104.585 123.090 83.589  1.00 117.05 ? 476  LYS A CA  1 
ATOM 3693 C C   . LYS A 1 476  ? 105.349 123.775 84.725  1.00 97.93  ? 476  LYS A C   1 
ATOM 3694 O O   . LYS A 1 476  ? 104.737 124.364 85.606  1.00 96.92  ? 476  LYS A O   1 
ATOM 3695 C CB  . LYS A 1 476  ? 103.545 122.124 84.168  1.00 127.88 ? 476  LYS A CB  1 
ATOM 3696 C CG  . LYS A 1 476  ? 102.650 121.446 83.139  1.00 134.33 ? 476  LYS A CG  1 
ATOM 3697 C CD  . LYS A 1 476  ? 102.466 119.965 83.390  1.00 138.10 ? 476  LYS A CD  1 
ATOM 3698 C CE  . LYS A 1 476  ? 101.826 119.654 84.726  1.00 137.77 ? 476  LYS A CE  1 
ATOM 3699 N NZ  . LYS A 1 476  ? 100.457 120.214 84.818  1.00 138.44 ? 476  LYS A NZ  1 
ATOM 3700 N N   . GLN A 1 477  ? 106.678 123.678 84.724  1.00 87.62  ? 477  GLN A N   1 
ATOM 3701 C CA  . GLN A 1 477  ? 107.512 124.473 85.611  1.00 82.70  ? 477  GLN A CA  1 
ATOM 3702 C C   . GLN A 1 477  ? 107.140 124.246 87.081  1.00 80.89  ? 477  GLN A C   1 
ATOM 3703 O O   . GLN A 1 477  ? 107.124 125.186 87.866  1.00 80.24  ? 477  GLN A O   1 
ATOM 3704 C CB  . GLN A 1 477  ? 107.402 125.951 85.230  1.00 82.79  ? 477  GLN A CB  1 
ATOM 3705 C CG  . GLN A 1 477  ? 108.747 126.664 85.178  1.00 96.41  ? 477  GLN A CG  1 
ATOM 3706 C CD  . GLN A 1 477  ? 109.711 126.190 86.239  1.00 107.86 ? 477  GLN A CD  1 
ATOM 3707 O OE1 . GLN A 1 477  ? 110.723 125.553 85.953  1.00 117.45 ? 477  GLN A OE1 1 
ATOM 3708 N NE2 . GLN A 1 477  ? 109.390 126.482 87.486  1.00 106.83 ? 477  GLN A NE2 1 
ATOM 3709 N N   . GLN A 1 478  ? 106.902 122.986 87.462  1.00 82.06  ? 478  GLN A N   1 
ATOM 3710 C CA  . GLN A 1 478  ? 106.606 122.628 88.840  1.00 75.64  ? 478  GLN A CA  1 
ATOM 3711 C C   . GLN A 1 478  ? 107.883 122.715 89.678  1.00 72.60  ? 478  GLN A C   1 
ATOM 3712 O O   . GLN A 1 478  ? 108.794 121.913 89.483  1.00 82.35  ? 478  GLN A O   1 
ATOM 3713 C CB  . GLN A 1 478  ? 106.095 121.185 88.924  1.00 79.89  ? 478  GLN A CB  1 
ATOM 3714 C CG  . GLN A 1 478  ? 104.868 120.879 88.077  1.00 86.34  ? 478  GLN A CG  1 
ATOM 3715 C CD  . GLN A 1 478  ? 104.451 119.430 88.194  1.00 86.98  ? 478  GLN A CD  1 
ATOM 3716 O OE1 . GLN A 1 478  ? 103.480 118.983 87.589  1.00 92.73  ? 478  GLN A OE1 1 
ATOM 3717 N NE2 . GLN A 1 478  ? 105.187 118.670 88.983  1.00 83.10  ? 478  GLN A NE2 1 
ATOM 3718 N N   . GLY A 1 479  ? 107.950 123.655 90.629  1.00 68.12  ? 479  GLY A N   1 
ATOM 3719 C CA  . GLY A 1 479  ? 109.136 123.787 91.467  1.00 71.18  ? 479  GLY A CA  1 
ATOM 3720 C C   . GLY A 1 479  ? 108.802 124.091 92.930  1.00 80.19  ? 479  GLY A C   1 
ATOM 3721 O O   . GLY A 1 479  ? 107.701 124.551 93.225  1.00 79.00  ? 479  GLY A O   1 
ATOM 3722 N N   . GLU A 1 480  ? 109.748 123.826 93.845  1.00 94.23  ? 480  GLU A N   1 
ATOM 3723 C CA  . GLU A 1 480  ? 109.596 124.193 95.245  1.00 113.09 ? 480  GLU A CA  1 
ATOM 3724 C C   . GLU A 1 480  ? 110.068 125.632 95.441  1.00 124.95 ? 480  GLU A C   1 
ATOM 3725 O O   . GLU A 1 480  ? 111.240 125.918 95.212  1.00 130.18 ? 480  GLU A O   1 
ATOM 3726 C CB  . GLU A 1 480  ? 110.438 123.300 96.155  1.00 129.55 ? 480  GLU A CB  1 
ATOM 3727 C CG  . GLU A 1 480  ? 109.999 121.849 96.186  1.00 153.14 ? 480  GLU A CG  1 
ATOM 3728 C CD  . GLU A 1 480  ? 110.828 120.966 97.107  1.00 175.29 ? 480  GLU A CD  1 
ATOM 3729 O OE1 . GLU A 1 480  ? 110.577 119.742 97.130  1.00 183.83 ? 480  GLU A OE1 1 
ATOM 3730 O OE2 . GLU A 1 480  ? 111.710 121.502 97.818  1.00 179.01 ? 480  GLU A OE2 1 
ATOM 3731 N N   . LEU A 1 481  ? 109.162 126.516 95.889  1.00 121.16 ? 481  LEU A N   1 
ATOM 3732 C CA  . LEU A 1 481  ? 109.466 127.929 96.065  1.00 109.74 ? 481  LEU A CA  1 
ATOM 3733 C C   . LEU A 1 481  ? 109.226 128.361 97.506  1.00 104.71 ? 481  LEU A C   1 
ATOM 3734 O O   . LEU A 1 481  ? 108.140 128.144 98.037  1.00 113.65 ? 481  LEU A O   1 
ATOM 3735 C CB  . LEU A 1 481  ? 108.573 128.756 95.137  1.00 114.76 ? 481  LEU A CB  1 
ATOM 3736 C CG  . LEU A 1 481  ? 109.049 128.896 93.695  1.00 129.29 ? 481  LEU A CG  1 
ATOM 3737 C CD1 . LEU A 1 481  ? 108.377 130.092 93.041  1.00 138.21 ? 481  LEU A CD1 1 
ATOM 3738 C CD2 . LEU A 1 481  ? 110.567 129.027 93.627  1.00 133.81 ? 481  LEU A CD2 1 
ATOM 3739 N N   . TYR A 1 482  ? 110.227 129.020 98.105  1.00 96.13  ? 482  TYR A N   1 
ATOM 3740 C CA  . TYR A 1 482  ? 110.052 129.649 99.405  1.00 94.53  ? 482  TYR A CA  1 
ATOM 3741 C C   . TYR A 1 482  ? 108.960 130.714 99.307  1.00 93.03  ? 482  TYR A C   1 
ATOM 3742 O O   . TYR A 1 482  ? 108.895 131.450 98.325  1.00 99.21  ? 482  TYR A O   1 
ATOM 3743 C CB  . TYR A 1 482  ? 111.372 130.242 99.906  1.00 94.06  ? 482  TYR A CB  1 
ATOM 3744 C CG  . TYR A 1 482  ? 112.336 129.288 100.564 1.00 100.59 ? 482  TYR A CG  1 
ATOM 3745 C CD1 . TYR A 1 482  ? 111.956 128.019 100.979 1.00 109.35 ? 482  TYR A CD1 1 
ATOM 3746 C CD2 . TYR A 1 482  ? 113.647 129.674 100.789 1.00 106.06 ? 482  TYR A CD2 1 
ATOM 3747 C CE1 . TYR A 1 482  ? 112.852 127.161 101.596 1.00 117.48 ? 482  TYR A CE1 1 
ATOM 3748 C CE2 . TYR A 1 482  ? 114.554 128.831 101.410 1.00 115.60 ? 482  TYR A CE2 1 
ATOM 3749 C CZ  . TYR A 1 482  ? 114.154 127.571 101.817 1.00 125.49 ? 482  TYR A CZ  1 
ATOM 3750 O OH  . TYR A 1 482  ? 115.053 126.730 102.429 1.00 140.97 ? 482  TYR A OH  1 
ATOM 3751 N N   . MET A 1 483  ? 108.094 130.765 100.324 1.00 89.44  ? 483  MET A N   1 
ATOM 3752 C CA  . MET A 1 483  ? 107.001 131.722 100.385 1.00 90.10  ? 483  MET A CA  1 
ATOM 3753 C C   . MET A 1 483  ? 107.118 132.499 101.697 1.00 110.01 ? 483  MET A C   1 
ATOM 3754 O O   . MET A 1 483  ? 107.492 131.922 102.713 1.00 121.32 ? 483  MET A O   1 
ATOM 3755 C CB  . MET A 1 483  ? 105.660 130.989 100.320 1.00 79.91  ? 483  MET A CB  1 
ATOM 3756 C CG  . MET A 1 483  ? 104.472 131.912 100.248 1.00 84.24  ? 483  MET A CG  1 
ATOM 3757 S SD  . MET A 1 483  ? 102.933 131.108 99.694  1.00 106.75 ? 483  MET A SD  1 
ATOM 3758 C CE  . MET A 1 483  ? 103.519 129.685 98.772  1.00 108.68 ? 483  MET A CE  1 
ATOM 3759 N N   . TRP A 1 484  ? 106.846 133.811 101.656 1.00 121.80 ? 484  TRP A N   1 
ATOM 3760 C CA  . TRP A 1 484  ? 106.906 134.682 102.824 1.00 130.48 ? 484  TRP A CA  1 
ATOM 3761 C C   . TRP A 1 484  ? 105.500 134.903 103.376 1.00 134.24 ? 484  TRP A C   1 
ATOM 3762 O O   . TRP A 1 484  ? 104.536 134.859 102.615 1.00 131.40 ? 484  TRP A O   1 
ATOM 3763 C CB  . TRP A 1 484  ? 107.549 136.024 102.454 1.00 140.66 ? 484  TRP A CB  1 
ATOM 3764 C CG  . TRP A 1 484  ? 107.499 137.054 103.540 1.00 151.90 ? 484  TRP A CG  1 
ATOM 3765 C CD1 . TRP A 1 484  ? 106.891 138.276 103.490 1.00 152.01 ? 484  TRP A CD1 1 
ATOM 3766 C CD2 . TRP A 1 484  ? 108.084 136.953 104.850 1.00 157.70 ? 484  TRP A CD2 1 
ATOM 3767 N NE1 . TRP A 1 484  ? 107.060 138.942 104.673 1.00 152.37 ? 484  TRP A NE1 1 
ATOM 3768 C CE2 . TRP A 1 484  ? 107.782 138.153 105.529 1.00 157.65 ? 484  TRP A CE2 1 
ATOM 3769 C CE3 . TRP A 1 484  ? 108.821 135.968 105.520 1.00 161.42 ? 484  TRP A CE3 1 
ATOM 3770 C CZ2 . TRP A 1 484  ? 108.204 138.394 106.837 1.00 162.35 ? 484  TRP A CZ2 1 
ATOM 3771 C CZ3 . TRP A 1 484  ? 109.247 136.212 106.808 1.00 160.44 ? 484  TRP A CZ3 1 
ATOM 3772 C CH2 . TRP A 1 484  ? 108.940 137.409 107.457 1.00 157.74 ? 484  TRP A CH2 1 
ATOM 3773 N N   . ASP A 1 485  ? 105.387 135.165 104.687 1.00 139.69 ? 485  ASP A N   1 
ATOM 3774 C CA  . ASP A 1 485  ? 104.086 135.392 105.301 1.00 157.18 ? 485  ASP A CA  1 
ATOM 3775 C C   . ASP A 1 485  ? 104.032 136.744 106.017 1.00 166.16 ? 485  ASP A C   1 
ATOM 3776 O O   . ASP A 1 485  ? 104.995 137.177 106.646 1.00 162.62 ? 485  ASP A O   1 
ATOM 3777 C CB  . ASP A 1 485  ? 103.719 134.256 106.260 1.00 172.96 ? 485  ASP A CB  1 
ATOM 3778 C CG  . ASP A 1 485  ? 103.486 132.914 105.584 1.00 189.29 ? 485  ASP A CG  1 
ATOM 3779 O OD1 . ASP A 1 485  ? 103.713 132.822 104.360 1.00 198.08 ? 485  ASP A OD1 1 
ATOM 3780 O OD2 . ASP A 1 485  ? 103.080 131.965 106.291 1.00 188.96 ? 485  ASP A OD2 1 
ATOM 3781 N N   . SER A 1 486  ? 102.848 137.371 105.956 1.00 181.08 ? 486  SER A N   1 
ATOM 3782 C CA  . SER A 1 486  ? 102.574 138.664 106.569 1.00 181.43 ? 486  SER A CA  1 
ATOM 3783 C C   . SER A 1 486  ? 102.572 138.566 108.095 1.00 164.07 ? 486  SER A C   1 
ATOM 3784 O O   . SER A 1 486  ? 103.013 139.494 108.774 1.00 163.07 ? 486  SER A O   1 
ATOM 3785 C CB  . SER A 1 486  ? 101.254 139.212 106.072 1.00 191.16 ? 486  SER A CB  1 
ATOM 3786 O OG  . SER A 1 486  ? 100.181 138.334 106.396 1.00 193.50 ? 486  SER A OG  1 
ATOM 3787 N N   . ILE A 1 487  ? 102.078 137.435 108.615 1.00 150.60 ? 487  ILE A N   1 
ATOM 3788 C CA  . ILE A 1 487  ? 101.823 137.261 110.038 1.00 147.26 ? 487  ILE A CA  1 
ATOM 3789 C C   . ILE A 1 487  ? 103.074 136.682 110.701 1.00 136.73 ? 487  ILE A C   1 
ATOM 3790 O O   . ILE A 1 487  ? 104.053 137.404 110.846 1.00 134.38 ? 487  ILE A O   1 
ATOM 3791 C CB  . ILE A 1 487  ? 100.503 136.495 110.303 1.00 170.50 ? 487  ILE A CB  1 
ATOM 3792 C CG1 . ILE A 1 487  ? 100.421 135.068 109.734 1.00 184.80 ? 487  ILE A CG1 1 
ATOM 3793 C CG2 . ILE A 1 487  ? 99.326  137.340 109.833 1.00 176.41 ? 487  ILE A CG2 1 
ATOM 3794 C CD1 . ILE A 1 487  ? 100.703 134.912 108.263 1.00 191.06 ? 487  ILE A CD1 1 
ATOM 3795 N N   . ASP A 1 488  ? 103.077 135.415 111.122 1.00 140.95 ? 488  ASP A N   1 
ATOM 3796 C CA  . ASP A 1 488  ? 104.281 134.841 111.701 1.00 152.85 ? 488  ASP A CA  1 
ATOM 3797 C C   . ASP A 1 488  ? 105.434 135.112 110.741 1.00 160.67 ? 488  ASP A C   1 
ATOM 3798 O O   . ASP A 1 488  ? 105.281 134.889 109.549 1.00 171.12 ? 488  ASP A O   1 
ATOM 3799 C CB  . ASP A 1 488  ? 104.097 133.349 111.982 1.00 159.51 ? 488  ASP A CB  1 
ATOM 3800 C CG  . ASP A 1 488  ? 102.895 133.050 112.861 1.00 169.98 ? 488  ASP A CG  1 
ATOM 3801 O OD1 . ASP A 1 488  ? 101.771 133.384 112.442 1.00 161.22 ? 488  ASP A OD1 1 
ATOM 3802 O OD2 . ASP A 1 488  ? 103.098 132.504 113.970 1.00 185.62 ? 488  ASP A OD2 1 
ATOM 3803 N N   . GLN A 1 489  ? 106.566 135.613 111.253 1.00 167.94 ? 489  GLN A N   1 
ATOM 3804 C CA  . GLN A 1 489  ? 107.616 136.167 110.403 1.00 177.47 ? 489  GLN A CA  1 
ATOM 3805 C C   . GLN A 1 489  ? 108.657 135.114 110.021 1.00 172.66 ? 489  GLN A C   1 
ATOM 3806 O O   . GLN A 1 489  ? 109.820 135.222 110.405 1.00 166.09 ? 489  GLN A O   1 
ATOM 3807 C CB  . GLN A 1 489  ? 108.319 137.338 111.097 1.00 189.67 ? 489  GLN A CB  1 
ATOM 3808 C CG  . GLN A 1 489  ? 107.422 138.531 111.403 1.00 197.27 ? 489  GLN A CG  1 
ATOM 3809 C CD  . GLN A 1 489  ? 106.825 139.182 110.177 1.00 201.80 ? 489  GLN A CD  1 
ATOM 3810 O OE1 . GLN A 1 489  ? 107.081 140.347 109.882 1.00 203.50 ? 489  GLN A OE1 1 
ATOM 3811 N NE2 . GLN A 1 489  ? 105.994 138.440 109.463 1.00 199.42 ? 489  GLN A NE2 1 
ATOM 3812 N N   . LYS A 1 490  ? 108.255 134.129 109.211 1.00 170.70 ? 490  LYS A N   1 
ATOM 3813 C CA  . LYS A 1 490  ? 109.205 133.197 108.626 1.00 167.07 ? 490  LYS A CA  1 
ATOM 3814 C C   . LYS A 1 490  ? 108.715 132.762 107.248 1.00 145.90 ? 490  LYS A C   1 
ATOM 3815 O O   . LYS A 1 490  ? 107.515 132.685 106.997 1.00 134.98 ? 490  LYS A O   1 
ATOM 3816 C CB  . LYS A 1 490  ? 109.435 131.986 109.538 1.00 184.69 ? 490  LYS A CB  1 
ATOM 3817 C CG  . LYS A 1 490  ? 108.184 131.264 110.029 1.00 201.94 ? 490  LYS A CG  1 
ATOM 3818 C CD  . LYS A 1 490  ? 107.764 131.595 111.454 1.00 217.43 ? 490  LYS A CD  1 
ATOM 3819 C CE  . LYS A 1 490  ? 108.848 131.361 112.488 1.00 229.07 ? 490  LYS A CE  1 
ATOM 3820 N NZ  . LYS A 1 490  ? 109.508 130.043 112.321 1.00 233.07 ? 490  LYS A NZ  1 
ATOM 3821 N N   . TRP A 1 491  ? 109.671 132.468 106.360 1.00 133.15 ? 491  TRP A N   1 
ATOM 3822 C CA  . TRP A 1 491  ? 109.362 131.907 105.057 1.00 121.83 ? 491  TRP A CA  1 
ATOM 3823 C C   . TRP A 1 491  ? 109.069 130.420 105.230 1.00 110.89 ? 491  TRP A C   1 
ATOM 3824 O O   . TRP A 1 491  ? 109.834 129.714 105.882 1.00 110.83 ? 491  TRP A O   1 
ATOM 3825 C CB  . TRP A 1 491  ? 110.512 132.117 104.066 1.00 127.50 ? 491  TRP A CB  1 
ATOM 3826 C CG  . TRP A 1 491  ? 110.928 133.542 103.866 1.00 129.00 ? 491  TRP A CG  1 
ATOM 3827 C CD1 . TRP A 1 491  ? 111.493 134.377 104.784 1.00 137.02 ? 491  TRP A CD1 1 
ATOM 3828 C CD2 . TRP A 1 491  ? 110.816 134.307 102.654 1.00 128.58 ? 491  TRP A CD2 1 
ATOM 3829 N NE1 . TRP A 1 491  ? 111.728 135.607 104.231 1.00 140.07 ? 491  TRP A NE1 1 
ATOM 3830 C CE2 . TRP A 1 491  ? 111.325 135.593 102.924 1.00 136.36 ? 491  TRP A CE2 1 
ATOM 3831 C CE3 . TRP A 1 491  ? 110.328 134.034 101.375 1.00 134.81 ? 491  TRP A CE3 1 
ATOM 3832 C CZ2 . TRP A 1 491  ? 111.361 136.595 101.957 1.00 149.26 ? 491  TRP A CZ2 1 
ATOM 3833 C CZ3 . TRP A 1 491  ? 110.362 135.024 100.421 1.00 143.39 ? 491  TRP A CZ3 1 
ATOM 3834 C CH2 . TRP A 1 491  ? 110.876 136.287 100.708 1.00 149.77 ? 491  TRP A CH2 1 
ATOM 3835 N N   . THR A 1 492  ? 107.967 129.955 104.635 1.00 104.77 ? 492  THR A N   1 
ATOM 3836 C CA  . THR A 1 492  ? 107.579 128.557 104.704 1.00 107.11 ? 492  THR A CA  1 
ATOM 3837 C C   . THR A 1 492  ? 107.632 127.956 103.302 1.00 108.33 ? 492  THR A C   1 
ATOM 3838 O O   . THR A 1 492  ? 106.999 128.474 102.391 1.00 107.66 ? 492  THR A O   1 
ATOM 3839 C CB  . THR A 1 492  ? 106.171 128.407 105.291 1.00 112.95 ? 492  THR A CB  1 
ATOM 3840 O OG1 . THR A 1 492  ? 105.243 128.928 104.339 1.00 115.14 ? 492  THR A OG1 1 
ATOM 3841 C CG2 . THR A 1 492  ? 106.007 129.111 106.620 1.00 116.84 ? 492  THR A CG2 1 
ATOM 3842 N N   . ARG A 1 493  ? 108.369 126.852 103.145 1.00 105.83 ? 493  ARG A N   1 
ATOM 3843 C CA  . ARG A 1 493  ? 108.592 126.243 101.842 1.00 96.40  ? 493  ARG A CA  1 
ATOM 3844 C C   . ARG A 1 493  ? 107.320 125.561 101.360 1.00 81.02  ? 493  ARG A C   1 
ATOM 3845 O O   . ARG A 1 493  ? 106.719 124.801 102.112 1.00 93.46  ? 493  ARG A O   1 
ATOM 3846 C CB  . ARG A 1 493  ? 109.709 125.200 101.936 1.00 105.31 ? 493  ARG A CB  1 
ATOM 3847 C CG  . ARG A 1 493  ? 110.009 124.490 100.626 1.00 118.79 ? 493  ARG A CG  1 
ATOM 3848 C CD  . ARG A 1 493  ? 111.063 123.408 100.788 1.00 131.04 ? 493  ARG A CD  1 
ATOM 3849 N NE  . ARG A 1 493  ? 112.354 123.907 101.247 1.00 132.61 ? 493  ARG A NE  1 
ATOM 3850 C CZ  . ARG A 1 493  ? 113.484 123.829 100.551 1.00 142.94 ? 493  ARG A CZ  1 
ATOM 3851 N NH1 . ARG A 1 493  ? 113.496 123.268 99.354  1.00 150.02 ? 493  ARG A NH1 1 
ATOM 3852 N NH2 . ARG A 1 493  ? 114.604 124.311 101.061 1.00 145.19 ? 493  ARG A NH2 1 
ATOM 3853 N N   . HIS A 1 494  ? 106.940 125.805 100.102 1.00 77.14  ? 494  HIS A N   1 
ATOM 3854 C CA  . HIS A 1 494  ? 105.828 125.100 99.482  1.00 88.24  ? 494  HIS A CA  1 
ATOM 3855 C C   . HIS A 1 494  ? 106.226 124.681 98.070  1.00 91.71  ? 494  HIS A C   1 
ATOM 3856 O O   . HIS A 1 494  ? 106.929 125.411 97.382  1.00 95.36  ? 494  HIS A O   1 
ATOM 3857 C CB  . HIS A 1 494  ? 104.576 125.980 99.381  1.00 96.95  ? 494  HIS A CB  1 
ATOM 3858 C CG  . HIS A 1 494  ? 104.105 126.604 100.653 1.00 106.95 ? 494  HIS A CG  1 
ATOM 3859 N ND1 . HIS A 1 494  ? 102.942 126.227 101.291 1.00 116.52 ? 494  HIS A ND1 1 
ATOM 3860 C CD2 . HIS A 1 494  ? 104.622 127.598 101.384 1.00 107.82 ? 494  HIS A CD2 1 
ATOM 3861 C CE1 . HIS A 1 494  ? 102.784 126.966 102.380 1.00 124.66 ? 494  HIS A CE1 1 
ATOM 3862 N NE2 . HIS A 1 494  ? 103.793 127.805 102.455 1.00 120.00 ? 494  HIS A NE2 1 
ATOM 3863 N N   . TYR A 1 495  ? 105.755 123.515 97.631  1.00 92.59  ? 495  TYR A N   1 
ATOM 3864 C CA  . TYR A 1 495  ? 105.897 123.117 96.242  1.00 99.77  ? 495  TYR A CA  1 
ATOM 3865 C C   . TYR A 1 495  ? 104.822 123.867 95.456  1.00 106.01 ? 495  TYR A C   1 
ATOM 3866 O O   . TYR A 1 495  ? 103.730 124.047 95.977  1.00 114.51 ? 495  TYR A O   1 
ATOM 3867 C CB  . TYR A 1 495  ? 105.784 121.591 96.177  1.00 107.13 ? 495  TYR A CB  1 
ATOM 3868 C CG  . TYR A 1 495  ? 106.071 120.941 94.849  1.00 103.80 ? 495  TYR A CG  1 
ATOM 3869 C CD1 . TYR A 1 495  ? 107.306 121.082 94.237  1.00 109.96 ? 495  TYR A CD1 1 
ATOM 3870 C CD2 . TYR A 1 495  ? 105.121 120.146 94.229  1.00 92.11  ? 495  TYR A CD2 1 
ATOM 3871 C CE1 . TYR A 1 495  ? 107.579 120.475 93.021  1.00 119.08 ? 495  TYR A CE1 1 
ATOM 3872 C CE2 . TYR A 1 495  ? 105.377 119.539 93.014  1.00 101.04 ? 495  TYR A CE2 1 
ATOM 3873 C CZ  . TYR A 1 495  ? 106.613 119.693 92.414  1.00 119.43 ? 495  TYR A CZ  1 
ATOM 3874 O OH  . TYR A 1 495  ? 106.890 119.092 91.211  1.00 131.96 ? 495  TYR A OH  1 
ATOM 3875 N N   . CYS A 1 496  ? 105.128 124.332 94.232  1.00 100.90 ? 496  CYS A N   1 
ATOM 3876 C CA  . CYS A 1 496  ? 104.192 125.142 93.455  1.00 95.97  ? 496  CYS A CA  1 
ATOM 3877 C C   . CYS A 1 496  ? 104.130 124.665 92.002  1.00 86.65  ? 496  CYS A C   1 
ATOM 3878 O O   . CYS A 1 496  ? 105.163 124.365 91.413  1.00 83.87  ? 496  CYS A O   1 
ATOM 3879 C CB  . CYS A 1 496  ? 104.592 126.616 93.459  1.00 110.93 ? 496  CYS A CB  1 
ATOM 3880 S SG  . CYS A 1 496  ? 105.736 127.073 94.791  1.00 126.92 ? 496  CYS A SG  1 
ATOM 3881 N N   . ALA A 1 497  ? 102.920 124.648 91.424  1.00 85.16  ? 497  ALA A N   1 
ATOM 3882 C CA  . ALA A 1 497  ? 102.678 124.151 90.075  1.00 98.73  ? 497  ALA A CA  1 
ATOM 3883 C C   . ALA A 1 497  ? 101.890 125.172 89.257  1.00 107.35 ? 497  ALA A C   1 
ATOM 3884 O O   . ALA A 1 497  ? 100.944 125.766 89.762  1.00 123.73 ? 497  ALA A O   1 
ATOM 3885 C CB  . ALA A 1 497  ? 101.913 122.849 90.138  1.00 100.67 ? 497  ALA A CB  1 
ATOM 3886 N N   . ILE A 1 498  ? 102.238 125.337 87.975  1.00 100.15 ? 498  ILE A N   1 
ATOM 3887 C CA  . ILE A 1 498  ? 101.536 126.274 87.108  1.00 89.10  ? 498  ILE A CA  1 
ATOM 3888 C C   . ILE A 1 498  ? 100.718 125.487 86.091  1.00 83.59  ? 498  ILE A C   1 
ATOM 3889 O O   . ILE A 1 498  ? 101.289 124.786 85.261  1.00 89.41  ? 498  ILE A O   1 
ATOM 3890 C CB  . ILE A 1 498  ? 102.518 127.224 86.394  1.00 93.29  ? 498  ILE A CB  1 
ATOM 3891 C CG1 . ILE A 1 498  ? 103.546 127.849 87.346  1.00 99.06  ? 498  ILE A CG1 1 
ATOM 3892 C CG2 . ILE A 1 498  ? 101.744 128.281 85.618  1.00 94.91  ? 498  ILE A CG2 1 
ATOM 3893 C CD1 . ILE A 1 498  ? 102.987 128.936 88.225  1.00 103.37 ? 498  ILE A CD1 1 
ATOM 3894 N N   . ALA A 1 499  ? 99.389  125.616 86.156  1.00 94.84  ? 499  ALA A N   1 
ATOM 3895 C CA  . ALA A 1 499  ? 98.519  125.095 85.112  1.00 120.85 ? 499  ALA A CA  1 
ATOM 3896 C C   . ALA A 1 499  ? 97.287  125.982 84.963  1.00 147.12 ? 499  ALA A C   1 
ATOM 3897 O O   . ALA A 1 499  ? 96.784  126.522 85.944  1.00 158.38 ? 499  ALA A O   1 
ATOM 3898 C CB  . ALA A 1 499  ? 98.119  123.677 85.419  1.00 121.72 ? 499  ALA A CB  1 
ATOM 3899 N N   . ASP A 1 500  ? 96.802  126.114 83.724  1.00 160.43 ? 500  ASP A N   1 
ATOM 3900 C CA  . ASP A 1 500  ? 95.583  126.858 83.452  1.00 162.71 ? 500  ASP A CA  1 
ATOM 3901 C C   . ASP A 1 500  ? 95.749  128.282 83.981  1.00 151.56 ? 500  ASP A C   1 
ATOM 3902 O O   . ASP A 1 500  ? 94.786  128.891 84.441  1.00 142.70 ? 500  ASP A O   1 
ATOM 3903 C CB  . ASP A 1 500  ? 94.375  126.149 84.073  1.00 174.34 ? 500  ASP A CB  1 
ATOM 3904 C CG  . ASP A 1 500  ? 94.581  124.653 84.235  1.00 187.75 ? 500  ASP A CG  1 
ATOM 3905 O OD1 . ASP A 1 500  ? 94.844  123.985 83.216  1.00 195.54 ? 500  ASP A OD1 1 
ATOM 3906 O OD2 . ASP A 1 500  ? 94.511  124.173 85.385  1.00 193.48 ? 500  ASP A OD2 1 
ATOM 3907 N N   . ALA A 1 501  ? 96.995  128.777 83.930  1.00 149.15 ? 501  ALA A N   1 
ATOM 3908 C CA  . ALA A 1 501  ? 97.357  130.113 84.379  1.00 151.12 ? 501  ALA A CA  1 
ATOM 3909 C C   . ALA A 1 501  ? 97.064  130.310 85.868  1.00 136.57 ? 501  ALA A C   1 
ATOM 3910 O O   . ALA A 1 501  ? 96.750  131.420 86.296  1.00 138.07 ? 501  ALA A O   1 
ATOM 3911 C CB  . ALA A 1 501  ? 96.644  131.142 83.534  1.00 162.24 ? 501  ALA A CB  1 
ATOM 3912 N N   . LYS A 1 502  ? 97.195  129.237 86.656  1.00 121.51 ? 502  LYS A N   1 
ATOM 3913 C CA  . LYS A 1 502  ? 96.996  129.309 88.094  1.00 108.72 ? 502  LYS A CA  1 
ATOM 3914 C C   . LYS A 1 502  ? 98.172  128.636 88.791  1.00 102.01 ? 502  LYS A C   1 
ATOM 3915 O O   . LYS A 1 502  ? 98.346  127.424 88.666  1.00 115.29 ? 502  LYS A O   1 
ATOM 3916 C CB  . LYS A 1 502  ? 95.694  128.610 88.492  1.00 107.30 ? 502  LYS A CB  1 
ATOM 3917 C CG  . LYS A 1 502  ? 94.438  129.164 87.835  1.00 119.14 ? 502  LYS A CG  1 
ATOM 3918 C CD  . LYS A 1 502  ? 93.385  128.114 87.562  1.00 137.09 ? 502  LYS A CD  1 
ATOM 3919 C CE  . LYS A 1 502  ? 92.836  127.463 88.816  1.00 151.66 ? 502  LYS A CE  1 
ATOM 3920 N NZ  . LYS A 1 502  ? 91.781  126.468 88.501  1.00 152.93 ? 502  LYS A NZ  1 
ATOM 3921 N N   . LEU A 1 503  ? 98.978  129.416 89.523  1.00 80.83  ? 503  LEU A N   1 
ATOM 3922 C CA  . LEU A 1 503  ? 99.898  128.803 90.463  1.00 66.52  ? 503  LEU A CA  1 
ATOM 3923 C C   . LEU A 1 503  ? 99.047  128.072 91.496  1.00 70.32  ? 503  LEU A C   1 
ATOM 3924 O O   . LEU A 1 503  ? 98.024  128.582 91.932  1.00 76.09  ? 503  LEU A O   1 
ATOM 3925 C CB  . LEU A 1 503  ? 100.819 129.848 91.094  1.00 59.33  ? 503  LEU A CB  1 
ATOM 3926 C CG  . LEU A 1 503  ? 102.014 129.275 91.859  1.00 63.56  ? 503  LEU A CG  1 
ATOM 3927 C CD1 . LEU A 1 503  ? 103.254 130.134 91.663  1.00 67.24  ? 503  LEU A CD1 1 
ATOM 3928 C CD2 . LEU A 1 503  ? 101.722 129.145 93.352  1.00 69.10  ? 503  LEU A CD2 1 
ATOM 3929 N N   . SER A 1 504  ? 99.417  126.828 91.783  1.00 76.99  ? 504  SER A N   1 
ATOM 3930 C CA  . SER A 1 504  ? 98.759  126.024 92.794  1.00 78.90  ? 504  SER A CA  1 
ATOM 3931 C C   . SER A 1 504  ? 99.815  125.643 93.824  1.00 85.34  ? 504  SER A C   1 
ATOM 3932 O O   . SER A 1 504  ? 100.913 125.230 93.465  1.00 78.90  ? 504  SER A O   1 
ATOM 3933 C CB  . SER A 1 504  ? 98.099  124.822 92.177  1.00 77.83  ? 504  SER A CB  1 
ATOM 3934 O OG  . SER A 1 504  ? 98.893  124.303 91.121  1.00 83.61  ? 504  SER A OG  1 
ATOM 3935 N N   . PHE A 1 505  ? 99.503  125.830 95.103  1.00 93.47  ? 505  PHE A N   1 
ATOM 3936 C CA  . PHE A 1 505  ? 100.497 125.608 96.135  1.00 98.07  ? 505  PHE A CA  1 
ATOM 3937 C C   . PHE A 1 505  ? 99.933  124.618 97.156  1.00 108.22 ? 505  PHE A C   1 
ATOM 3938 O O   . PHE A 1 505  ? 98.729  124.394 97.234  1.00 105.65 ? 505  PHE A O   1 
ATOM 3939 C CB  . PHE A 1 505  ? 101.053 126.948 96.647  1.00 96.64  ? 505  PHE A CB  1 
ATOM 3940 C CG  . PHE A 1 505  ? 100.177 127.832 97.503  1.00 103.13 ? 505  PHE A CG  1 
ATOM 3941 C CD1 . PHE A 1 505  ? 99.744  127.425 98.755  1.00 117.95 ? 505  PHE A CD1 1 
ATOM 3942 C CD2 . PHE A 1 505  ? 99.891  129.128 97.102  1.00 114.28 ? 505  PHE A CD2 1 
ATOM 3943 C CE1 . PHE A 1 505  ? 98.984  128.266 99.552  1.00 133.66 ? 505  PHE A CE1 1 
ATOM 3944 C CE2 . PHE A 1 505  ? 99.135  129.974 97.897  1.00 131.42 ? 505  PHE A CE2 1 
ATOM 3945 C CZ  . PHE A 1 505  ? 98.680  129.539 99.120  1.00 140.42 ? 505  PHE A CZ  1 
ATOM 3946 N N   . SER A 1 506  ? 100.861 123.987 97.879  1.00 111.15 ? 506  SER A N   1 
ATOM 3947 C CA  . SER A 1 506  ? 100.582 122.919 98.820  1.00 102.09 ? 506  SER A CA  1 
ATOM 3948 C C   . SER A 1 506  ? 101.081 123.334 100.197 1.00 105.94 ? 506  SER A C   1 
ATOM 3949 O O   . SER A 1 506  ? 101.979 124.166 100.292 1.00 101.98 ? 506  SER A O   1 
ATOM 3950 C CB  . SER A 1 506  ? 101.275 121.674 98.391  1.00 104.30 ? 506  SER A CB  1 
ATOM 3951 O OG  . SER A 1 506  ? 102.680 121.828 98.541  1.00 104.42 ? 506  SER A OG  1 
ATOM 3952 N N   . ASP A 1 507  ? 100.548 122.686 101.238 1.00 110.59 ? 507  ASP A N   1 
ATOM 3953 C CA  . ASP A 1 507  ? 100.895 122.992 102.619 1.00 117.78 ? 507  ASP A CA  1 
ATOM 3954 C C   . ASP A 1 507  ? 102.414 123.004 102.809 1.00 101.95 ? 507  ASP A C   1 
ATOM 3955 O O   . ASP A 1 507  ? 103.162 122.464 101.998 1.00 102.03 ? 507  ASP A O   1 
ATOM 3956 C CB  . ASP A 1 507  ? 100.248 121.991 103.580 1.00 140.25 ? 507  ASP A CB  1 
ATOM 3957 C CG  . ASP A 1 507  ? 98.730  121.947 103.495 1.00 154.25 ? 507  ASP A CG  1 
ATOM 3958 O OD1 . ASP A 1 507  ? 98.209  121.656 102.393 1.00 159.07 ? 507  ASP A OD1 1 
ATOM 3959 O OD2 . ASP A 1 507  ? 98.079  122.210 104.528 1.00 158.05 ? 507  ASP A OD2 1 
ATOM 3960 N N   . ASP A 1 508  ? 102.853 123.601 103.920 1.00 96.74  ? 508  ASP A N   1 
ATOM 3961 C CA  . ASP A 1 508  ? 104.262 123.851 104.172 1.00 104.53 ? 508  ASP A CA  1 
ATOM 3962 C C   . ASP A 1 508  ? 105.023 122.526 104.227 1.00 98.85  ? 508  ASP A C   1 
ATOM 3963 O O   . ASP A 1 508  ? 104.553 121.564 104.816 1.00 98.46  ? 508  ASP A O   1 
ATOM 3964 C CB  . ASP A 1 508  ? 104.429 124.656 105.465 1.00 122.73 ? 508  ASP A CB  1 
ATOM 3965 C CG  . ASP A 1 508  ? 105.857 125.052 105.797 1.00 141.69 ? 508  ASP A CG  1 
ATOM 3966 O OD1 . ASP A 1 508  ? 106.756 124.745 104.988 1.00 153.88 ? 508  ASP A OD1 1 
ATOM 3967 O OD2 . ASP A 1 508  ? 106.059 125.660 106.872 1.00 148.98 ? 508  ASP A OD2 1 
ATOM 3968 N N   . ILE A 1 509  ? 106.219 122.505 103.632 1.00 104.63 ? 509  ILE A N   1 
ATOM 3969 C CA  . ILE A 1 509  ? 107.121 121.369 103.734 1.00 116.03 ? 509  ILE A CA  1 
ATOM 3970 C C   . ILE A 1 509  ? 107.672 121.345 105.157 1.00 135.22 ? 509  ILE A C   1 
ATOM 3971 O O   . ILE A 1 509  ? 107.912 122.399 105.735 1.00 143.14 ? 509  ILE A O   1 
ATOM 3972 C CB  . ILE A 1 509  ? 108.261 121.476 102.697 1.00 128.85 ? 509  ILE A CB  1 
ATOM 3973 C CG1 . ILE A 1 509  ? 107.750 121.697 101.268 1.00 137.17 ? 509  ILE A CG1 1 
ATOM 3974 C CG2 . ILE A 1 509  ? 109.189 120.272 102.780 1.00 138.93 ? 509  ILE A CG2 1 
ATOM 3975 C CD1 . ILE A 1 509  ? 106.785 120.643 100.771 1.00 141.39 ? 509  ILE A CD1 1 
ATOM 3976 N N   . GLU A 1 510  ? 107.880 120.149 105.720 1.00 161.08 ? 510  GLU A N   1 
ATOM 3977 C CA  . GLU A 1 510  ? 108.490 120.004 107.037 1.00 178.36 ? 510  GLU A CA  1 
ATOM 3978 C C   . GLU A 1 510  ? 109.547 121.096 107.264 1.00 159.04 ? 510  GLU A C   1 
ATOM 3979 O O   . GLU A 1 510  ? 110.710 120.888 106.852 1.00 134.78 ? 510  GLU A O   1 
ATOM 3980 C CB  . GLU A 1 510  ? 109.108 118.612 107.191 1.00 212.13 ? 510  GLU A CB  1 
ATOM 3981 C CG  . GLU A 1 510  ? 108.082 117.494 107.282 1.00 238.35 ? 510  GLU A CG  1 
ATOM 3982 C CD  . GLU A 1 510  ? 108.671 116.103 107.449 1.00 259.58 ? 510  GLU A CD  1 
ATOM 3983 O OE1 . GLU A 1 510  ? 108.444 115.255 106.561 1.00 268.73 ? 510  GLU A OE1 1 
ATOM 3984 O OE2 . GLU A 1 510  ? 109.354 115.869 108.467 1.00 270.24 ? 510  GLU A OE2 1 
ATOM 3985 N N   . LEU A 1 526  ? 119.825 129.600 133.362 1.00 558.71 ? 526  LEU A N   1 
ATOM 3986 C CA  . LEU A 1 526  ? 119.797 128.115 133.234 1.00 562.23 ? 526  LEU A CA  1 
ATOM 3987 C C   . LEU A 1 526  ? 118.670 127.530 134.085 1.00 556.33 ? 526  LEU A C   1 
ATOM 3988 O O   . LEU A 1 526  ? 117.995 126.599 133.653 1.00 550.07 ? 526  LEU A O   1 
ATOM 3989 C CB  . LEU A 1 526  ? 121.155 127.537 133.654 1.00 572.19 ? 526  LEU A CB  1 
ATOM 3990 C CG  . LEU A 1 526  ? 122.317 127.803 132.697 1.00 582.43 ? 526  LEU A CG  1 
ATOM 3991 C CD1 . LEU A 1 526  ? 123.625 127.292 133.280 1.00 585.28 ? 526  LEU A CD1 1 
ATOM 3992 C CD2 . LEU A 1 526  ? 122.066 127.168 131.335 1.00 587.72 ? 526  LEU A CD2 1 
ATOM 3993 N N   . HIS A 1 527  ? 118.471 128.086 135.289 1.00 558.02 ? 527  HIS A N   1 
ATOM 3994 C CA  . HIS A 1 527  ? 117.538 127.527 136.256 1.00 561.59 ? 527  HIS A CA  1 
ATOM 3995 C C   . HIS A 1 527  ? 116.087 127.737 135.819 1.00 542.97 ? 527  HIS A C   1 
ATOM 3996 O O   . HIS A 1 527  ? 115.203 127.031 136.295 1.00 545.68 ? 527  HIS A O   1 
ATOM 3997 C CB  . HIS A 1 527  ? 117.800 128.078 137.665 1.00 575.88 ? 527  HIS A CB  1 
ATOM 3998 C CG  . HIS A 1 527  ? 117.503 129.533 137.838 1.00 581.70 ? 527  HIS A CG  1 
ATOM 3999 N ND1 . HIS A 1 527  ? 118.392 130.539 137.523 1.00 583.20 ? 527  HIS A ND1 1 
ATOM 4000 C CD2 . HIS A 1 527  ? 116.420 130.141 138.338 1.00 582.50 ? 527  HIS A CD2 1 
ATOM 4001 C CE1 . HIS A 1 527  ? 117.844 131.712 137.807 1.00 581.75 ? 527  HIS A CE1 1 
ATOM 4002 N NE2 . HIS A 1 527  ? 116.645 131.494 138.302 1.00 580.85 ? 527  HIS A NE2 1 
ATOM 4003 N N   . PHE A 1 528  ? 115.847 128.692 134.909 1.00 520.12 ? 528  PHE A N   1 
ATOM 4004 C CA  . PHE A 1 528  ? 114.504 128.986 134.426 1.00 506.47 ? 528  PHE A CA  1 
ATOM 4005 C C   . PHE A 1 528  ? 113.961 127.853 133.554 1.00 496.70 ? 528  PHE A C   1 
ATOM 4006 O O   . PHE A 1 528  ? 112.749 127.750 133.372 1.00 497.53 ? 528  PHE A O   1 
ATOM 4007 C CB  . PHE A 1 528  ? 114.489 130.311 133.659 1.00 505.39 ? 528  PHE A CB  1 
ATOM 4008 C CG  . PHE A 1 528  ? 114.541 131.538 134.533 1.00 506.97 ? 528  PHE A CG  1 
ATOM 4009 C CD1 . PHE A 1 528  ? 113.458 131.890 135.325 1.00 506.18 ? 528  PHE A CD1 1 
ATOM 4010 C CD2 . PHE A 1 528  ? 115.675 132.337 134.574 1.00 512.04 ? 528  PHE A CD2 1 
ATOM 4011 C CE1 . PHE A 1 528  ? 113.505 133.017 136.132 1.00 508.42 ? 528  PHE A CE1 1 
ATOM 4012 C CE2 . PHE A 1 528  ? 115.720 133.463 135.382 1.00 514.67 ? 528  PHE A CE2 1 
ATOM 4013 C CZ  . PHE A 1 528  ? 114.636 133.801 136.160 1.00 512.44 ? 528  PHE A CZ  1 
ATOM 4014 N N   . GLY A 1 529  ? 114.856 127.016 133.009 1.00 485.91 ? 529  GLY A N   1 
ATOM 4015 C CA  . GLY A 1 529  ? 114.459 125.890 132.178 1.00 479.48 ? 529  GLY A CA  1 
ATOM 4016 C C   . GLY A 1 529  ? 114.388 124.572 132.950 1.00 472.57 ? 529  GLY A C   1 
ATOM 4017 O O   . GLY A 1 529  ? 114.093 123.533 132.363 1.00 473.13 ? 529  GLY A O   1 
ATOM 4018 N N   . GLU A 1 530  ? 114.645 124.624 134.264 1.00 463.56 ? 530  GLU A N   1 
ATOM 4019 C CA  . GLU A 1 530  ? 114.753 123.427 135.084 1.00 453.06 ? 530  GLU A CA  1 
ATOM 4020 C C   . GLU A 1 530  ? 113.395 123.068 135.682 1.00 420.77 ? 530  GLU A C   1 
ATOM 4021 O O   . GLU A 1 530  ? 112.661 123.931 136.160 1.00 415.43 ? 530  GLU A O   1 
ATOM 4022 C CB  . GLU A 1 530  ? 115.785 123.626 136.195 1.00 468.69 ? 530  GLU A CB  1 
ATOM 4023 C CG  . GLU A 1 530  ? 117.216 123.657 135.691 1.00 483.55 ? 530  GLU A CG  1 
ATOM 4024 C CD  . GLU A 1 530  ? 117.721 122.322 135.170 1.00 493.85 ? 530  GLU A CD  1 
ATOM 4025 O OE1 . GLU A 1 530  ? 118.119 122.261 133.990 1.00 499.30 ? 530  GLU A OE1 1 
ATOM 4026 O OE2 . GLU A 1 530  ? 117.706 121.346 135.946 1.00 499.56 ? 530  GLU A OE2 1 
ATOM 4027 N N   . LYS A 1 531  ? 113.107 121.763 135.684 1.00 399.86 ? 531  LYS A N   1 
ATOM 4028 C CA  . LYS A 1 531  ? 111.868 121.214 136.207 1.00 393.58 ? 531  LYS A CA  1 
ATOM 4029 C C   . LYS A 1 531  ? 111.644 121.676 137.648 1.00 393.19 ? 531  LYS A C   1 
ATOM 4030 O O   . LYS A 1 531  ? 110.525 122.005 138.038 1.00 390.20 ? 531  LYS A O   1 
ATOM 4031 C CB  . LYS A 1 531  ? 111.935 119.686 136.099 1.00 395.80 ? 531  LYS A CB  1 
ATOM 4032 C CG  . LYS A 1 531  ? 111.900 119.136 134.678 1.00 403.43 ? 531  LYS A CG  1 
ATOM 4033 C CD  . LYS A 1 531  ? 111.853 117.625 134.620 1.00 413.50 ? 531  LYS A CD  1 
ATOM 4034 C CE  . LYS A 1 531  ? 111.803 117.088 133.205 1.00 419.61 ? 531  LYS A CE  1 
ATOM 4035 N NZ  . LYS A 1 531  ? 111.735 115.608 133.183 1.00 420.79 ? 531  LYS A NZ  1 
ATOM 4036 N N   . TRP A 1 532  ? 112.727 121.725 138.429 1.00 398.92 ? 532  TRP A N   1 
ATOM 4037 C CA  . TRP A 1 532  ? 112.633 121.905 139.870 1.00 413.44 ? 532  TRP A CA  1 
ATOM 4038 C C   . TRP A 1 532  ? 112.371 123.359 140.258 1.00 418.46 ? 532  TRP A C   1 
ATOM 4039 O O   . TRP A 1 532  ? 112.117 123.631 141.426 1.00 423.96 ? 532  TRP A O   1 
ATOM 4040 C CB  . TRP A 1 532  ? 113.890 121.364 140.568 1.00 419.62 ? 532  TRP A CB  1 
ATOM 4041 C CG  . TRP A 1 532  ? 115.185 121.735 139.912 1.00 415.78 ? 532  TRP A CG  1 
ATOM 4042 C CD1 . TRP A 1 532  ? 115.943 120.934 139.108 1.00 417.98 ? 532  TRP A CD1 1 
ATOM 4043 C CD2 . TRP A 1 532  ? 115.899 122.981 140.024 1.00 411.20 ? 532  TRP A CD2 1 
ATOM 4044 N NE1 . TRP A 1 532  ? 117.064 121.600 138.692 1.00 418.93 ? 532  TRP A NE1 1 
ATOM 4045 C CE2 . TRP A 1 532  ? 117.067 122.855 139.241 1.00 415.60 ? 532  TRP A CE2 1 
ATOM 4046 C CE3 . TRP A 1 532  ? 115.665 124.190 140.693 1.00 409.26 ? 532  TRP A CE3 1 
ATOM 4047 C CZ2 . TRP A 1 532  ? 117.993 123.889 139.115 1.00 421.30 ? 532  TRP A CZ2 1 
ATOM 4048 C CZ3 . TRP A 1 532  ? 116.580 125.212 140.565 1.00 414.08 ? 532  TRP A CZ3 1 
ATOM 4049 C CH2 . TRP A 1 532  ? 117.728 125.061 139.787 1.00 422.36 ? 532  TRP A CH2 1 
ATOM 4050 N N   . PHE A 1 533  ? 112.465 124.303 139.317 1.00 427.14 ? 533  PHE A N   1 
ATOM 4051 C CA  . PHE A 1 533  ? 112.268 125.698 139.678 1.00 442.90 ? 533  PHE A CA  1 
ATOM 4052 C C   . PHE A 1 533  ? 110.786 126.040 139.530 1.00 435.98 ? 533  PHE A C   1 
ATOM 4053 O O   . PHE A 1 533  ? 110.184 125.739 138.502 1.00 437.00 ? 533  PHE A O   1 
ATOM 4054 C CB  . PHE A 1 533  ? 113.189 126.604 138.856 1.00 463.45 ? 533  PHE A CB  1 
ATOM 4055 C CG  . PHE A 1 533  ? 113.109 128.065 139.223 1.00 484.73 ? 533  PHE A CG  1 
ATOM 4056 C CD1 . PHE A 1 533  ? 113.371 128.487 140.518 1.00 494.16 ? 533  PHE A CD1 1 
ATOM 4057 C CD2 . PHE A 1 533  ? 112.763 129.017 138.276 1.00 495.46 ? 533  PHE A CD2 1 
ATOM 4058 C CE1 . PHE A 1 533  ? 113.288 129.830 140.856 1.00 500.00 ? 533  PHE A CE1 1 
ATOM 4059 C CE2 . PHE A 1 533  ? 112.683 130.359 138.617 1.00 496.29 ? 533  PHE A CE2 1 
ATOM 4060 C CZ  . PHE A 1 533  ? 112.946 130.763 139.905 1.00 499.33 ? 533  PHE A CZ  1 
ATOM 4061 N N   . HIS A 1 534  ? 110.202 126.655 140.570 1.00 428.19 ? 534  HIS A N   1 
ATOM 4062 C CA  . HIS A 1 534  ? 108.776 126.950 140.591 1.00 419.16 ? 534  HIS A CA  1 
ATOM 4063 C C   . HIS A 1 534  ? 108.509 128.456 140.639 1.00 444.97 ? 534  HIS A C   1 
ATOM 4064 O O   . HIS A 1 534  ? 107.433 128.874 141.067 1.00 450.03 ? 534  HIS A O   1 
ATOM 4065 C CB  . HIS A 1 534  ? 108.101 126.222 141.761 1.00 395.18 ? 534  HIS A CB  1 
ATOM 4066 C CG  . HIS A 1 534  ? 108.108 124.739 141.619 1.00 372.05 ? 534  HIS A CG  1 
ATOM 4067 N ND1 . HIS A 1 534  ? 106.955 123.987 141.560 1.00 364.23 ? 534  HIS A ND1 1 
ATOM 4068 C CD2 . HIS A 1 534  ? 109.121 123.877 141.519 1.00 361.40 ? 534  HIS A CD2 1 
ATOM 4069 C CE1 . HIS A 1 534  ? 107.280 122.711 141.431 1.00 363.18 ? 534  HIS A CE1 1 
ATOM 4070 N NE2 . HIS A 1 534  ? 108.592 122.620 141.404 1.00 363.85 ? 534  HIS A NE2 1 
ATOM 4071 N N   . LYS A 1 535  ? 109.480 129.261 140.180 1.00 464.26 ? 535  LYS A N   1 
ATOM 4072 C CA  . LYS A 1 535  ? 109.351 130.712 140.133 1.00 475.39 ? 535  LYS A CA  1 
ATOM 4073 C C   . LYS A 1 535  ? 108.639 131.203 141.397 1.00 500.09 ? 535  LYS A C   1 
ATOM 4074 O O   . LYS A 1 535  ? 109.022 130.825 142.504 1.00 511.86 ? 535  LYS A O   1 
ATOM 4075 C CB  . LYS A 1 535  ? 108.656 131.128 138.830 1.00 469.46 ? 535  LYS A CB  1 
ATOM 4076 C CG  . LYS A 1 535  ? 109.405 130.779 137.550 1.00 469.93 ? 535  LYS A CG  1 
ATOM 4077 C CD  . LYS A 1 535  ? 108.674 131.186 136.288 1.00 471.31 ? 535  LYS A CD  1 
ATOM 4078 C CE  . LYS A 1 535  ? 109.496 130.976 135.034 1.00 471.95 ? 535  LYS A CE  1 
ATOM 4079 N NZ  . LYS A 1 535  ? 108.744 131.365 133.816 1.00 469.27 ? 535  LYS A NZ  1 
ATOM 4080 N N   . LYS A 1 536  ? 107.608 132.044 141.227 1.00 522.91 ? 536  LYS A N   1 
ATOM 4081 C CA  . LYS A 1 536  ? 106.841 132.571 142.343 1.00 550.21 ? 536  LYS A CA  1 
ATOM 4082 C C   . LYS A 1 536  ? 105.696 131.618 142.674 1.00 571.70 ? 536  LYS A C   1 
ATOM 4083 O O   . LYS A 1 536  ? 104.674 131.612 141.990 1.00 564.88 ? 536  LYS A O   1 
ATOM 4084 C CB  . LYS A 1 536  ? 106.294 133.964 142.011 1.00 561.12 ? 536  LYS A CB  1 
ATOM 4085 C CG  . LYS A 1 536  ? 107.340 135.066 141.915 1.00 576.03 ? 536  LYS A CG  1 
ATOM 4086 C CD  . LYS A 1 536  ? 106.758 136.431 141.616 1.00 590.10 ? 536  LYS A CD  1 
ATOM 4087 C CE  . LYS A 1 536  ? 107.801 137.528 141.588 1.00 599.60 ? 536  LYS A CE  1 
ATOM 4088 N NZ  . LYS A 1 536  ? 107.198 138.849 141.292 1.00 602.18 ? 536  LYS A NZ  1 
ATOM 4089 N N   . VAL A 1 537  ? 105.892 130.806 143.720 1.00 607.55 ? 537  VAL A N   1 
ATOM 4090 C CA  . VAL A 1 537  ? 104.810 130.064 144.345 1.00 637.27 ? 537  VAL A CA  1 
ATOM 4091 C C   . VAL A 1 537  ? 104.232 130.951 145.446 1.00 675.74 ? 537  VAL A C   1 
ATOM 4092 O O   . VAL A 1 537  ? 104.957 131.375 146.344 1.00 684.31 ? 537  VAL A O   1 
ATOM 4093 C CB  . VAL A 1 537  ? 105.296 128.704 144.883 1.00 634.93 ? 537  VAL A CB  1 
ATOM 4094 C CG1 . VAL A 1 537  ? 104.178 127.926 145.563 1.00 632.96 ? 537  VAL A CG1 1 
ATOM 4095 C CG2 . VAL A 1 537  ? 105.940 127.868 143.786 1.00 632.33 ? 537  VAL A CG2 1 
ATOM 4096 N N   . GLU A 1 538  ? 102.921 131.213 145.365 1.00 716.20 ? 538  GLU A N   1 
ATOM 4097 C CA  . GLU A 1 538  ? 102.283 132.306 146.085 1.00 751.96 ? 538  GLU A CA  1 
ATOM 4098 C C   . GLU A 1 538  ? 102.386 132.130 147.600 1.00 780.16 ? 538  GLU A C   1 
ATOM 4099 O O   . GLU A 1 538  ? 102.395 133.122 148.327 1.00 785.93 ? 538  GLU A O   1 
ATOM 4100 C CB  . GLU A 1 538  ? 100.812 132.420 145.682 1.00 760.15 ? 538  GLU A CB  1 
ATOM 4101 C CG  . GLU A 1 538  ? 100.608 132.821 144.231 1.00 764.41 ? 538  GLU A CG  1 
ATOM 4102 C CD  . GLU A 1 538  ? 99.158  132.946 143.793 1.00 768.24 ? 538  GLU A CD  1 
ATOM 4103 O OE1 . GLU A 1 538  ? 98.928  133.275 142.613 1.00 767.66 ? 538  GLU A OE1 1 
ATOM 4104 O OE2 . GLU A 1 538  ? 98.263  132.714 144.630 1.00 772.23 ? 538  GLU A OE2 1 
ATOM 4105 N N   . LYS A 1 539  ? 102.433 130.877 148.072 1.00 805.78 ? 539  LYS A N   1 
ATOM 4106 C CA  . LYS A 1 539  ? 102.413 130.591 149.499 1.00 825.98 ? 539  LYS A CA  1 
ATOM 4107 C C   . LYS A 1 539  ? 103.246 129.349 149.809 1.00 818.14 ? 539  LYS A C   1 
ATOM 4108 O O   . LYS A 1 539  ? 103.295 128.411 149.016 1.00 811.13 ? 539  LYS A O   1 
ATOM 4109 C CB  . LYS A 1 539  ? 100.973 130.385 149.982 1.00 849.10 ? 539  LYS A CB  1 
ATOM 4110 C CG  . LYS A 1 539  ? 100.066 131.605 149.877 1.00 866.04 ? 539  LYS A CG  1 
ATOM 4111 C CD  . LYS A 1 539  ? 98.698  131.391 150.489 1.00 878.63 ? 539  LYS A CD  1 
ATOM 4112 C CE  . LYS A 1 539  ? 97.806  132.611 150.387 1.00 886.45 ? 539  LYS A CE  1 
ATOM 4113 N NZ  . LYS A 1 539  ? 96.476  132.369 150.995 1.00 889.09 ? 539  LYS A NZ  1 
ATOM 4114 N N   . ARG A 1 540  ? 103.873 129.350 150.993 1.00 811.38 ? 540  ARG A N   1 
ATOM 4115 C CA  . ARG A 1 540  ? 104.643 128.216 151.482 1.00 804.71 ? 540  ARG A CA  1 
ATOM 4116 C C   . ARG A 1 540  ? 103.797 126.944 151.431 1.00 790.39 ? 540  ARG A C   1 
ATOM 4117 O O   . ARG A 1 540  ? 104.307 125.878 151.092 1.00 765.68 ? 540  ARG A O   1 
ATOM 4118 C CB  . ARG A 1 540  ? 105.128 128.484 152.911 1.00 815.16 ? 540  ARG A CB  1 
ATOM 4119 C CG  . ARG A 1 540  ? 105.783 127.286 153.583 1.00 824.80 ? 540  ARG A CG  1 
ATOM 4120 C CD  . ARG A 1 540  ? 106.188 127.550 155.020 1.00 835.39 ? 540  ARG A CD  1 
ATOM 4121 N NE  . ARG A 1 540  ? 106.356 126.289 155.731 1.00 843.65 ? 540  ARG A NE  1 
ATOM 4122 C CZ  . ARG A 1 540  ? 107.484 125.863 156.289 1.00 853.63 ? 540  ARG A CZ  1 
ATOM 4123 N NH1 . ARG A 1 540  ? 108.559 126.633 156.311 1.00 857.40 ? 540  ARG A NH1 1 
ATOM 4124 N NH2 . ARG A 1 540  ? 107.529 124.660 156.835 1.00 855.73 ? 540  ARG A NH2 1 
ATOM 4125 N N   . THR A 1 541  ? 102.508 127.074 151.773 1.00 787.03 ? 541  THR A N   1 
ATOM 4126 C CA  . THR A 1 541  ? 101.584 125.952 151.840 1.00 778.84 ? 541  THR A CA  1 
ATOM 4127 C C   . THR A 1 541  ? 101.408 125.294 150.471 1.00 740.57 ? 541  THR A C   1 
ATOM 4128 O O   . THR A 1 541  ? 101.164 124.090 150.396 1.00 734.83 ? 541  THR A O   1 
ATOM 4129 C CB  . THR A 1 541  ? 100.226 126.399 152.398 1.00 798.62 ? 541  THR A CB  1 
ATOM 4130 O OG1 . THR A 1 541  ? 99.765  127.505 151.620 1.00 806.62 ? 541  THR A OG1 1 
ATOM 4131 C CG2 . THR A 1 541  ? 100.291 126.799 153.856 1.00 805.94 ? 541  THR A CG2 1 
ATOM 4132 N N   . SER A 1 542  ? 101.508 126.091 149.399 1.00 694.64 ? 542  SER A N   1 
ATOM 4133 C CA  . SER A 1 542  ? 101.387 125.585 148.041 1.00 653.14 ? 542  SER A CA  1 
ATOM 4134 C C   . SER A 1 542  ? 102.584 124.701 147.692 1.00 595.89 ? 542  SER A C   1 
ATOM 4135 O O   . SER A 1 542  ? 102.413 123.655 147.071 1.00 599.90 ? 542  SER A O   1 
ATOM 4136 C CB  . SER A 1 542  ? 101.228 126.714 147.056 1.00 657.94 ? 542  SER A CB  1 
ATOM 4137 O OG  . SER A 1 542  ? 100.085 127.495 147.368 1.00 661.50 ? 542  SER A OG  1 
ATOM 4138 N N   . ALA A 1 543  ? 103.787 125.127 148.101 1.00 524.92 ? 543  ALA A N   1 
ATOM 4139 C CA  . ALA A 1 543  ? 105.002 124.352 147.891 1.00 469.72 ? 543  ALA A CA  1 
ATOM 4140 C C   . ALA A 1 543  ? 104.934 123.034 148.661 1.00 434.88 ? 543  ALA A C   1 
ATOM 4141 O O   . ALA A 1 543  ? 105.366 121.999 148.156 1.00 411.45 ? 543  ALA A O   1 
ATOM 4142 C CB  . ALA A 1 543  ? 106.209 125.163 148.300 1.00 459.63 ? 543  ALA A CB  1 
ATOM 4143 N N   . GLU A 1 544  ? 104.392 123.084 149.885 1.00 430.10 ? 544  GLU A N   1 
ATOM 4144 C CA  . GLU A 1 544  ? 104.233 121.900 150.715 1.00 434.51 ? 544  GLU A CA  1 
ATOM 4145 C C   . GLU A 1 544  ? 103.264 120.922 150.052 1.00 443.87 ? 544  GLU A C   1 
ATOM 4146 O O   . GLU A 1 544  ? 103.520 119.721 150.026 1.00 434.04 ? 544  GLU A O   1 
ATOM 4147 C CB  . GLU A 1 544  ? 103.745 122.285 152.114 1.00 440.53 ? 544  GLU A CB  1 
ATOM 4148 C CG  . GLU A 1 544  ? 104.802 122.972 152.962 1.00 448.22 ? 544  GLU A CG  1 
ATOM 4149 C CD  . GLU A 1 544  ? 104.326 123.458 154.322 1.00 454.78 ? 544  GLU A CD  1 
ATOM 4150 O OE1 . GLU A 1 544  ? 105.185 123.832 155.147 1.00 462.97 ? 544  GLU A OE1 1 
ATOM 4151 O OE2 . GLU A 1 544  ? 103.099 123.473 154.550 1.00 454.90 ? 544  GLU A OE2 1 
ATOM 4152 N N   . LYS A 1 545  ? 102.157 121.449 149.512 1.00 469.36 ? 545  LYS A N   1 
ATOM 4153 C CA  . LYS A 1 545  ? 101.125 120.636 148.886 1.00 489.09 ? 545  LYS A CA  1 
ATOM 4154 C C   . LYS A 1 545  ? 101.688 119.905 147.667 1.00 479.47 ? 545  LYS A C   1 
ATOM 4155 O O   . LYS A 1 545  ? 101.447 118.713 147.501 1.00 472.45 ? 545  LYS A O   1 
ATOM 4156 C CB  . LYS A 1 545  ? 99.930  121.512 148.492 1.00 511.40 ? 545  LYS A CB  1 
ATOM 4157 C CG  . LYS A 1 545  ? 98.771  120.779 147.830 1.00 523.27 ? 545  LYS A CG  1 
ATOM 4158 C CD  . LYS A 1 545  ? 97.611  121.683 147.471 1.00 529.21 ? 545  LYS A CD  1 
ATOM 4159 C CE  . LYS A 1 545  ? 96.552  120.991 146.639 1.00 531.33 ? 545  LYS A CE  1 
ATOM 4160 N NZ  . LYS A 1 545  ? 95.389  121.874 146.388 1.00 532.01 ? 545  LYS A NZ  1 
ATOM 4161 N N   . LEU A 1 546  ? 102.432 120.634 146.822 1.00 463.88 ? 546  LEU A N   1 
ATOM 4162 C CA  . LEU A 1 546  ? 102.984 120.085 145.591 1.00 442.75 ? 546  LEU A CA  1 
ATOM 4163 C C   . LEU A 1 546  ? 103.923 118.920 145.897 1.00 399.03 ? 546  LEU A C   1 
ATOM 4164 O O   . LEU A 1 546  ? 103.900 117.909 145.196 1.00 394.38 ? 546  LEU A O   1 
ATOM 4165 C CB  . LEU A 1 546  ? 103.726 121.190 144.828 1.00 456.70 ? 546  LEU A CB  1 
ATOM 4166 C CG  . LEU A 1 546  ? 102.848 122.246 144.159 1.00 469.14 ? 546  LEU A CG  1 
ATOM 4167 C CD1 . LEU A 1 546  ? 103.704 123.339 143.536 1.00 470.50 ? 546  LEU A CD1 1 
ATOM 4168 C CD2 . LEU A 1 546  ? 101.936 121.621 143.112 1.00 472.82 ? 546  LEU A CD2 1 
ATOM 4169 N N   . LEU A 1 547  ? 104.753 119.081 146.934 1.00 357.65 ? 547  LEU A N   1 
ATOM 4170 C CA  . LEU A 1 547  ? 105.695 118.051 147.347 1.00 330.70 ? 547  LEU A CA  1 
ATOM 4171 C C   . LEU A 1 547  ? 104.947 116.842 147.908 1.00 312.87 ? 547  LEU A C   1 
ATOM 4172 O O   . LEU A 1 547  ? 105.284 115.704 147.583 1.00 297.47 ? 547  LEU A O   1 
ATOM 4173 C CB  . LEU A 1 547  ? 106.672 118.649 148.368 1.00 328.67 ? 547  LEU A CB  1 
ATOM 4174 C CG  . LEU A 1 547  ? 107.997 119.132 147.779 1.00 330.46 ? 547  LEU A CG  1 
ATOM 4175 C CD1 . LEU A 1 547  ? 108.590 120.273 148.593 1.00 332.15 ? 547  LEU A CD1 1 
ATOM 4176 C CD2 . LEU A 1 547  ? 108.986 117.981 147.691 1.00 336.22 ? 547  LEU A CD2 1 
ATOM 4177 N N   . GLN A 1 548  ? 103.932 117.101 148.743 1.00 314.45 ? 548  GLN A N   1 
ATOM 4178 C CA  . GLN A 1 548  ? 103.140 116.042 149.347 1.00 321.13 ? 548  GLN A CA  1 
ATOM 4179 C C   . GLN A 1 548  ? 102.489 115.199 148.254 1.00 317.46 ? 548  GLN A C   1 
ATOM 4180 O O   . GLN A 1 548  ? 102.518 113.975 148.326 1.00 318.71 ? 548  GLN A O   1 
ATOM 4181 C CB  . GLN A 1 548  ? 102.100 116.622 150.309 1.00 336.26 ? 548  GLN A CB  1 
ATOM 4182 C CG  . GLN A 1 548  ? 102.689 117.070 151.640 1.00 357.00 ? 548  GLN A CG  1 
ATOM 4183 C CD  . GLN A 1 548  ? 101.692 117.807 152.501 1.00 372.36 ? 548  GLN A CD  1 
ATOM 4184 O OE1 . GLN A 1 548  ? 100.512 117.912 152.174 1.00 376.01 ? 548  GLN A OE1 1 
ATOM 4185 N NE2 . GLN A 1 548  ? 102.165 118.324 153.624 1.00 379.08 ? 548  GLN A NE2 1 
ATOM 4186 N N   . GLU A 1 549  ? 101.919 115.858 147.238 1.00 322.05 ? 549  GLU A N   1 
ATOM 4187 C CA  . GLU A 1 549  ? 101.303 115.152 146.124 1.00 327.43 ? 549  GLU A CA  1 
ATOM 4188 C C   . GLU A 1 549  ? 102.329 114.238 145.461 1.00 322.85 ? 549  GLU A C   1 
ATOM 4189 O O   . GLU A 1 549  ? 102.238 113.014 145.555 1.00 323.08 ? 549  GLU A O   1 
ATOM 4190 C CB  . GLU A 1 549  ? 100.755 116.126 145.079 1.00 330.46 ? 549  GLU A CB  1 
ATOM 4191 C CG  . GLU A 1 549  ? 99.625  117.000 145.587 1.00 328.66 ? 549  GLU A CG  1 
ATOM 4192 C CD  . GLU A 1 549  ? 99.071  117.969 144.556 1.00 320.89 ? 549  GLU A CD  1 
ATOM 4193 O OE1 . GLU A 1 549  ? 98.148  118.726 144.904 1.00 320.99 ? 549  GLU A OE1 1 
ATOM 4194 O OE2 . GLU A 1 549  ? 99.560  117.962 143.407 1.00 311.64 ? 549  GLU A OE2 1 
ATOM 4195 N N   . TYR A 1 550  ? 103.315 114.860 144.807 1.00 320.14 ? 550  TYR A N   1 
ATOM 4196 C CA  . TYR A 1 550  ? 104.295 114.137 144.019 1.00 320.81 ? 550  TYR A CA  1 
ATOM 4197 C C   . TYR A 1 550  ? 104.803 112.953 144.830 1.00 323.77 ? 550  TYR A C   1 
ATOM 4198 O O   . TYR A 1 550  ? 105.077 111.893 144.279 1.00 322.15 ? 550  TYR A O   1 
ATOM 4199 C CB  . TYR A 1 550  ? 105.433 115.076 143.609 1.00 325.58 ? 550  TYR A CB  1 
ATOM 4200 C CG  . TYR A 1 550  ? 106.438 114.531 142.624 1.00 329.28 ? 550  TYR A CG  1 
ATOM 4201 C CD1 . TYR A 1 550  ? 106.063 114.172 141.340 1.00 324.02 ? 550  TYR A CD1 1 
ATOM 4202 C CD2 . TYR A 1 550  ? 107.782 114.424 142.957 1.00 340.86 ? 550  TYR A CD2 1 
ATOM 4203 C CE1 . TYR A 1 550  ? 106.988 113.699 140.422 1.00 324.30 ? 550  TYR A CE1 1 
ATOM 4204 C CE2 . TYR A 1 550  ? 108.721 113.950 142.054 1.00 341.34 ? 550  TYR A CE2 1 
ATOM 4205 C CZ  . TYR A 1 550  ? 108.321 113.585 140.780 1.00 331.41 ? 550  TYR A CZ  1 
ATOM 4206 O OH  . TYR A 1 550  ? 109.240 113.111 139.875 1.00 330.05 ? 550  TYR A OH  1 
ATOM 4207 N N   . CYS A 1 551  ? 104.917 113.140 146.145 1.00 343.69 ? 551  CYS A N   1 
ATOM 4208 C CA  . CYS A 1 551  ? 105.467 112.082 146.969 1.00 372.98 ? 551  CYS A CA  1 
ATOM 4209 C C   . CYS A 1 551  ? 104.425 110.992 147.209 1.00 393.73 ? 551  CYS A C   1 
ATOM 4210 O O   . CYS A 1 551  ? 104.779 109.817 147.249 1.00 403.74 ? 551  CYS A O   1 
ATOM 4211 C CB  . CYS A 1 551  ? 106.040 112.633 148.267 1.00 385.94 ? 551  CYS A CB  1 
ATOM 4212 S SG  . CYS A 1 551  ? 107.569 113.571 148.009 1.00 404.67 ? 551  CYS A SG  1 
ATOM 4213 N N   . MET A 1 552  ? 103.152 111.378 147.347 1.00 409.57 ? 552  MET A N   1 
ATOM 4214 C CA  . MET A 1 552  ? 102.080 110.422 147.576 1.00 424.04 ? 552  MET A CA  1 
ATOM 4215 C C   . MET A 1 552  ? 101.891 109.535 146.346 1.00 423.64 ? 552  MET A C   1 
ATOM 4216 O O   . MET A 1 552  ? 101.647 108.337 146.485 1.00 418.24 ? 552  MET A O   1 
ATOM 4217 C CB  . MET A 1 552  ? 100.760 111.132 147.897 1.00 437.60 ? 552  MET A CB  1 
ATOM 4218 C CG  . MET A 1 552  ? 100.613 111.492 149.361 1.00 449.25 ? 552  MET A CG  1 
ATOM 4219 S SD  . MET A 1 552  ? 99.089  112.410 149.690 1.00 464.77 ? 552  MET A SD  1 
ATOM 4220 C CE  . MET A 1 552  ? 97.914  111.061 149.781 1.00 470.01 ? 552  MET A CE  1 
ATOM 4221 N N   . GLU A 1 553  ? 102.026 110.117 145.149 1.00 427.92 ? 553  GLU A N   1 
ATOM 4222 C CA  . GLU A 1 553  ? 101.656 109.414 143.930 1.00 432.20 ? 553  GLU A CA  1 
ATOM 4223 C C   . GLU A 1 553  ? 102.658 108.297 143.619 1.00 425.98 ? 553  GLU A C   1 
ATOM 4224 O O   . GLU A 1 553  ? 102.262 107.133 143.573 1.00 418.71 ? 553  GLU A O   1 
ATOM 4225 C CB  . GLU A 1 553  ? 101.442 110.421 142.798 1.00 437.63 ? 553  GLU A CB  1 
ATOM 4226 C CG  . GLU A 1 553  ? 100.281 111.360 143.093 1.00 440.13 ? 553  GLU A CG  1 
ATOM 4227 C CD  . GLU A 1 553  ? 99.786  112.217 141.941 1.00 439.72 ? 553  GLU A CD  1 
ATOM 4228 O OE1 . GLU A 1 553  ? 98.805  112.959 142.144 1.00 442.42 ? 553  GLU A OE1 1 
ATOM 4229 O OE2 . GLU A 1 553  ? 100.385 112.156 140.848 1.00 435.35 ? 553  GLU A OE2 1 
ATOM 4230 N N   . THR A 1 554  ? 103.946 108.626 143.434 1.00 422.89 ? 554  THR A N   1 
ATOM 4231 C CA  . THR A 1 554  ? 104.916 107.637 142.980 1.00 416.89 ? 554  THR A CA  1 
ATOM 4232 C C   . THR A 1 554  ? 105.584 106.899 144.143 1.00 418.63 ? 554  THR A C   1 
ATOM 4233 O O   . THR A 1 554  ? 106.090 105.800 143.938 1.00 416.84 ? 554  THR A O   1 
ATOM 4234 C CB  . THR A 1 554  ? 105.995 108.250 142.076 1.00 412.41 ? 554  THR A CB  1 
ATOM 4235 O OG1 . THR A 1 554  ? 106.723 109.230 142.816 1.00 413.40 ? 554  THR A OG1 1 
ATOM 4236 C CG2 . THR A 1 554  ? 105.428 108.868 140.817 1.00 411.39 ? 554  THR A CG2 1 
ATOM 4237 N N   . GLY A 1 555  ? 105.621 107.492 145.345 1.00 419.54 ? 555  GLY A N   1 
ATOM 4238 C CA  . GLY A 1 555  ? 106.316 106.879 146.471 1.00 413.09 ? 555  GLY A CA  1 
ATOM 4239 C C   . GLY A 1 555  ? 107.569 107.665 146.844 1.00 399.91 ? 555  GLY A C   1 
ATOM 4240 O O   . GLY A 1 555  ? 108.672 107.119 146.918 1.00 387.24 ? 555  GLY A O   1 
ATOM 4241 N N   . GLY A 1 556  ? 107.347 108.951 147.132 1.00 392.48 ? 556  GLY A N   1 
ATOM 4242 C CA  . GLY A 1 556  ? 108.389 109.958 147.240 1.00 384.17 ? 556  GLY A CA  1 
ATOM 4243 C C   . GLY A 1 556  ? 109.565 109.536 148.117 1.00 376.17 ? 556  GLY A C   1 
ATOM 4244 O O   . GLY A 1 556  ? 109.382 108.984 149.202 1.00 366.41 ? 556  GLY A O   1 
ATOM 4245 N N   . LYS A 1 557  ? 110.774 109.832 147.624 1.00 382.17 ? 557  LYS A N   1 
ATOM 4246 C CA  . LYS A 1 557  ? 112.011 109.567 148.339 1.00 391.92 ? 557  LYS A CA  1 
ATOM 4247 C C   . LYS A 1 557  ? 112.435 110.826 149.089 1.00 420.92 ? 557  LYS A C   1 
ATOM 4248 O O   . LYS A 1 557  ? 112.112 111.941 148.679 1.00 426.48 ? 557  LYS A O   1 
ATOM 4249 C CB  . LYS A 1 557  ? 113.109 109.149 147.355 1.00 383.16 ? 557  LYS A CB  1 
ATOM 4250 C CG  . LYS A 1 557  ? 112.793 107.923 146.508 1.00 381.08 ? 557  LYS A CG  1 
ATOM 4251 C CD  . LYS A 1 557  ? 113.794 107.679 145.400 1.00 381.18 ? 557  LYS A CD  1 
ATOM 4252 C CE  . LYS A 1 557  ? 113.432 106.494 144.530 1.00 382.20 ? 557  LYS A CE  1 
ATOM 4253 N NZ  . LYS A 1 557  ? 114.421 106.289 143.445 1.00 383.49 ? 557  LYS A NZ  1 
ATOM 4254 N N   . ASP A 1 558  ? 113.175 110.638 150.187 1.00 457.12 ? 558  ASP A N   1 
ATOM 4255 C CA  . ASP A 1 558  ? 113.785 111.757 150.885 1.00 488.24 ? 558  ASP A CA  1 
ATOM 4256 C C   . ASP A 1 558  ? 114.700 112.489 149.905 1.00 509.56 ? 558  ASP A C   1 
ATOM 4257 O O   . ASP A 1 558  ? 115.422 111.861 149.130 1.00 523.15 ? 558  ASP A O   1 
ATOM 4258 C CB  . ASP A 1 558  ? 114.510 111.306 152.158 1.00 494.68 ? 558  ASP A CB  1 
ATOM 4259 C CG  . ASP A 1 558  ? 113.598 111.131 153.362 1.00 496.15 ? 558  ASP A CG  1 
ATOM 4260 O OD1 . ASP A 1 558  ? 112.364 111.128 153.173 1.00 495.39 ? 558  ASP A OD1 1 
ATOM 4261 O OD2 . ASP A 1 558  ? 114.124 111.041 154.489 1.00 496.83 ? 558  ASP A OD2 1 
ATOM 4262 N N   . GLY A 1 559  ? 114.620 113.824 149.921 1.00 514.28 ? 559  GLY A N   1 
ATOM 4263 C CA  . GLY A 1 559  ? 115.397 114.659 149.021 1.00 512.83 ? 559  GLY A CA  1 
ATOM 4264 C C   . GLY A 1 559  ? 114.618 115.107 147.783 1.00 506.89 ? 559  GLY A C   1 
ATOM 4265 O O   . GLY A 1 559  ? 115.146 115.883 146.991 1.00 503.95 ? 559  GLY A O   1 
ATOM 4266 N N   . THR A 1 560  ? 113.386 114.607 147.596 1.00 503.04 ? 560  THR A N   1 
ATOM 4267 C CA  . THR A 1 560  ? 112.502 115.127 146.560 1.00 500.87 ? 560  THR A CA  1 
ATOM 4268 C C   . THR A 1 560  ? 112.318 116.621 146.811 1.00 495.87 ? 560  THR A C   1 
ATOM 4269 O O   . THR A 1 560  ? 112.006 116.999 147.935 1.00 501.27 ? 560  THR A O   1 
ATOM 4270 C CB  . THR A 1 560  ? 111.144 114.407 146.554 1.00 507.96 ? 560  THR A CB  1 
ATOM 4271 O OG1 . THR A 1 560  ? 111.345 112.999 146.424 1.00 508.93 ? 560  THR A OG1 1 
ATOM 4272 C CG2 . THR A 1 560  ? 110.227 114.868 145.440 1.00 512.51 ? 560  THR A CG2 1 
ATOM 4273 N N   . PHE A 1 561  ? 112.508 117.468 145.785 1.00 490.26 ? 561  PHE A N   1 
ATOM 4274 C CA  . PHE A 1 561  ? 112.664 118.893 146.045 1.00 491.92 ? 561  PHE A CA  1 
ATOM 4275 C C   . PHE A 1 561  ? 112.100 119.782 144.935 1.00 504.02 ? 561  PHE A C   1 
ATOM 4276 O O   . PHE A 1 561  ? 111.894 119.349 143.800 1.00 494.20 ? 561  PHE A O   1 
ATOM 4277 C CB  . PHE A 1 561  ? 114.141 119.232 146.260 1.00 483.17 ? 561  PHE A CB  1 
ATOM 4278 C CG  . PHE A 1 561  ? 114.969 119.280 145.000 1.00 474.99 ? 561  PHE A CG  1 
ATOM 4279 C CD1 . PHE A 1 561  ? 115.367 118.115 144.360 1.00 469.23 ? 561  PHE A CD1 1 
ATOM 4280 C CD2 . PHE A 1 561  ? 115.330 120.496 144.439 1.00 475.51 ? 561  PHE A CD2 1 
ATOM 4281 C CE1 . PHE A 1 561  ? 116.123 118.166 143.199 1.00 472.81 ? 561  PHE A CE1 1 
ATOM 4282 C CE2 . PHE A 1 561  ? 116.086 120.545 143.278 1.00 477.26 ? 561  PHE A CE2 1 
ATOM 4283 C CZ  . PHE A 1 561  ? 116.483 119.381 142.660 1.00 478.38 ? 561  PHE A CZ  1 
ATOM 4284 N N   . LEU A 1 562  ? 111.864 121.049 145.320 1.00 526.89 ? 562  LEU A N   1 
ATOM 4285 C CA  . LEU A 1 562  ? 111.612 122.155 144.407 1.00 544.70 ? 562  LEU A CA  1 
ATOM 4286 C C   . LEU A 1 562  ? 112.269 123.427 144.949 1.00 553.72 ? 562  LEU A C   1 
ATOM 4287 O O   . LEU A 1 562  ? 112.571 123.520 146.140 1.00 559.85 ? 562  LEU A O   1 
ATOM 4288 C CB  . LEU A 1 562  ? 110.101 122.355 144.217 1.00 552.65 ? 562  LEU A CB  1 
ATOM 4289 C CG  . LEU A 1 562  ? 109.272 122.691 145.460 1.00 562.50 ? 562  LEU A CG  1 
ATOM 4290 C CD1 . LEU A 1 562  ? 109.258 124.190 145.742 1.00 569.53 ? 562  LEU A CD1 1 
ATOM 4291 C CD2 . LEU A 1 562  ? 107.846 122.179 145.311 1.00 561.54 ? 562  LEU A CD2 1 
ATOM 4292 N N   . VAL A 1 563  ? 112.478 124.402 144.053 1.00 561.06 ? 563  VAL A N   1 
ATOM 4293 C CA  . VAL A 1 563  ? 113.009 125.710 144.409 1.00 566.19 ? 563  VAL A CA  1 
ATOM 4294 C C   . VAL A 1 563  ? 112.032 126.781 143.928 1.00 597.56 ? 563  VAL A C   1 
ATOM 4295 O O   . VAL A 1 563  ? 111.505 126.689 142.821 1.00 599.54 ? 563  VAL A O   1 
ATOM 4296 C CB  . VAL A 1 563  ? 114.412 125.943 143.812 1.00 542.79 ? 563  VAL A CB  1 
ATOM 4297 C CG1 . VAL A 1 563  ? 114.955 127.321 144.167 1.00 538.03 ? 563  VAL A CG1 1 
ATOM 4298 C CG2 . VAL A 1 563  ? 115.396 124.859 144.223 1.00 531.04 ? 563  VAL A CG2 1 
ATOM 4299 N N   . ARG A 1 564  ? 111.823 127.803 144.770 1.00 624.54 ? 564  ARG A N   1 
ATOM 4300 C CA  . ARG A 1 564  ? 110.918 128.904 144.474 1.00 643.34 ? 564  ARG A CA  1 
ATOM 4301 C C   . ARG A 1 564  ? 111.545 130.212 144.946 1.00 664.42 ? 564  ARG A C   1 
ATOM 4302 O O   . ARG A 1 564  ? 112.457 130.196 145.768 1.00 671.30 ? 564  ARG A O   1 
ATOM 4303 C CB  . ARG A 1 564  ? 109.570 128.683 145.169 1.00 638.45 ? 564  ARG A CB  1 
ATOM 4304 C CG  . ARG A 1 564  ? 109.663 128.531 146.682 1.00 626.58 ? 564  ARG A CG  1 
ATOM 4305 C CD  . ARG A 1 564  ? 108.308 128.310 147.324 1.00 614.38 ? 564  ARG A CD  1 
ATOM 4306 N NE  . ARG A 1 564  ? 108.398 128.182 148.773 1.00 599.70 ? 564  ARG A NE  1 
ATOM 4307 C CZ  . ARG A 1 564  ? 108.131 129.159 149.633 1.00 587.49 ? 564  ARG A CZ  1 
ATOM 4308 N NH1 . ARG A 1 564  ? 107.870 130.376 149.193 1.00 586.59 ? 564  ARG A NH1 1 
ATOM 4309 N NH2 . ARG A 1 564  ? 108.149 128.922 150.933 1.00 582.88 ? 564  ARG A NH2 1 
ATOM 4310 N N   . GLU A 1 565  ? 111.042 131.341 144.430 1.00 685.70 ? 565  GLU A N   1 
ATOM 4311 C CA  . GLU A 1 565  ? 111.432 132.648 144.935 1.00 704.45 ? 565  GLU A CA  1 
ATOM 4312 C C   . GLU A 1 565  ? 110.935 132.787 146.373 1.00 724.76 ? 565  GLU A C   1 
ATOM 4313 O O   . GLU A 1 565  ? 109.876 132.263 146.715 1.00 721.65 ? 565  GLU A O   1 
ATOM 4314 C CB  . GLU A 1 565  ? 110.879 133.768 144.049 1.00 706.38 ? 565  GLU A CB  1 
ATOM 4315 C CG  . GLU A 1 565  ? 111.541 133.847 142.684 1.00 709.77 ? 565  GLU A CG  1 
ATOM 4316 C CD  . GLU A 1 565  ? 111.110 135.017 141.815 1.00 713.27 ? 565  GLU A CD  1 
ATOM 4317 O OE1 . GLU A 1 565  ? 111.565 135.086 140.656 1.00 715.58 ? 565  GLU A OE1 1 
ATOM 4318 O OE2 . GLU A 1 565  ? 110.328 135.861 142.297 1.00 714.66 ? 565  GLU A OE2 1 
ATOM 4319 N N   . SER A 1 566  ? 111.718 133.481 147.208 1.00 756.73 ? 566  SER A N   1 
ATOM 4320 C CA  . SER A 1 566  ? 111.379 133.663 148.611 1.00 786.74 ? 566  SER A CA  1 
ATOM 4321 C C   . SER A 1 566  ? 110.360 134.791 148.758 1.00 827.87 ? 566  SER A C   1 
ATOM 4322 O O   . SER A 1 566  ? 110.620 135.923 148.355 1.00 831.63 ? 566  SER A O   1 
ATOM 4323 C CB  . SER A 1 566  ? 112.610 133.933 149.440 1.00 785.85 ? 566  SER A CB  1 
ATOM 4324 O OG  . SER A 1 566  ? 112.299 133.925 150.827 1.00 784.95 ? 566  SER A OG  1 
ATOM 4325 N N   . GLU A 1 567  ? 109.203 134.462 149.349 1.00 875.12 ? 567  GLU A N   1 
ATOM 4326 C CA  . GLU A 1 567  ? 108.170 135.437 149.666 1.00 915.00 ? 567  GLU A CA  1 
ATOM 4327 C C   . GLU A 1 567  ? 108.687 136.464 150.671 1.00 954.07 ? 567  GLU A C   1 
ATOM 4328 O O   . GLU A 1 567  ? 108.291 137.627 150.625 1.00 962.54 ? 567  GLU A O   1 
ATOM 4329 C CB  . GLU A 1 567  ? 106.948 134.743 150.271 1.00 914.31 ? 567  GLU A CB  1 
ATOM 4330 C CG  . GLU A 1 567  ? 106.176 133.875 149.295 1.00 909.21 ? 567  GLU A CG  1 
ATOM 4331 C CD  . GLU A 1 567  ? 105.325 132.811 149.967 1.00 900.64 ? 567  GLU A CD  1 
ATOM 4332 O OE1 . GLU A 1 567  ? 105.438 131.634 149.573 1.00 892.22 ? 567  GLU A OE1 1 
ATOM 4333 O OE2 . GLU A 1 567  ? 104.579 133.158 150.905 1.00 898.04 ? 567  GLU A OE2 1 
ATOM 4334 N N   . THR A 1 568  ? 109.555 136.010 151.586 1.00 990.36 ? 568  THR A N   1 
ATOM 4335 C CA  . THR A 1 568  ? 109.959 136.790 152.747 1.00 999.00 ? 568  THR A CA  1 
ATOM 4336 C C   . THR A 1 568  ? 111.181 137.653 152.435 1.00 999.00 ? 568  THR A C   1 
ATOM 4337 O O   . THR A 1 568  ? 111.365 138.700 153.054 1.00 999.00 ? 568  THR A O   1 
ATOM 4338 C CB  . THR A 1 568  ? 110.249 135.870 153.941 1.00 999.00 ? 568  THR A CB  1 
ATOM 4339 O OG1 . THR A 1 568  ? 109.185 134.923 154.047 1.00 999.00 ? 568  THR A OG1 1 
ATOM 4340 C CG2 . THR A 1 568  ? 110.389 136.619 155.248 1.00 999.00 ? 568  THR A CG2 1 
ATOM 4341 N N   . PHE A 1 569  ? 112.017 137.205 151.489 1.00 999.00 ? 569  PHE A N   1 
ATOM 4342 C CA  . PHE A 1 569  ? 113.304 137.835 151.238 1.00 999.00 ? 569  PHE A CA  1 
ATOM 4343 C C   . PHE A 1 569  ? 113.469 138.091 149.741 1.00 999.00 ? 569  PHE A C   1 
ATOM 4344 O O   . PHE A 1 569  ? 113.758 137.169 148.983 1.00 999.00 ? 569  PHE A O   1 
ATOM 4345 C CB  . PHE A 1 569  ? 114.424 136.957 151.801 1.00 999.00 ? 569  PHE A CB  1 
ATOM 4346 C CG  . PHE A 1 569  ? 114.314 136.691 153.282 1.00 999.00 ? 569  PHE A CG  1 
ATOM 4347 C CD1 . PHE A 1 569  ? 114.596 137.687 154.205 1.00 999.00 ? 569  PHE A CD1 1 
ATOM 4348 C CD2 . PHE A 1 569  ? 113.905 135.452 153.753 1.00 999.00 ? 569  PHE A CD2 1 
ATOM 4349 C CE1 . PHE A 1 569  ? 114.488 137.445 155.567 1.00 999.00 ? 569  PHE A CE1 1 
ATOM 4350 C CE2 . PHE A 1 569  ? 113.797 135.212 155.115 1.00 999.00 ? 569  PHE A CE2 1 
ATOM 4351 C CZ  . PHE A 1 569  ? 114.088 136.208 156.019 1.00 999.00 ? 569  PHE A CZ  1 
ATOM 4352 N N   . PRO A 1 570  ? 113.280 139.345 149.265 1.00 999.00 ? 570  PRO A N   1 
ATOM 4353 C CA  . PRO A 1 570  ? 113.507 139.680 147.857 1.00 999.00 ? 570  PRO A CA  1 
ATOM 4354 C C   . PRO A 1 570  ? 114.895 139.263 147.372 1.00 999.00 ? 570  PRO A C   1 
ATOM 4355 O O   . PRO A 1 570  ? 115.873 139.419 148.100 1.00 999.00 ? 570  PRO A O   1 
ATOM 4356 C CB  . PRO A 1 570  ? 113.356 141.209 147.819 1.00 999.00 ? 570  PRO A CB  1 
ATOM 4357 C CG  . PRO A 1 570  ? 112.447 141.522 148.987 1.00 999.00 ? 570  PRO A CG  1 
ATOM 4358 C CD  . PRO A 1 570  ? 112.806 140.499 150.045 1.00 999.00 ? 570  PRO A CD  1 
ATOM 4359 N N   . ASN A 1 571  ? 114.940 138.700 146.156 1.00 999.00 ? 571  ASN A N   1 
ATOM 4360 C CA  . ASN A 1 571  ? 116.162 138.293 145.471 1.00 999.00 ? 571  ASN A CA  1 
ATOM 4361 C C   . ASN A 1 571  ? 116.687 136.956 146.001 1.00 999.00 ? 571  ASN A C   1 
ATOM 4362 O O   . ASN A 1 571  ? 117.629 136.410 145.429 1.00 999.00 ? 571  ASN A O   1 
ATOM 4363 C CB  . ASN A 1 571  ? 117.259 139.365 145.511 1.00 999.00 ? 571  ASN A CB  1 
ATOM 4364 C CG  . ASN A 1 571  ? 116.816 140.691 144.926 1.00 999.00 ? 571  ASN A CG  1 
ATOM 4365 O OD1 . ASN A 1 571  ? 116.033 140.725 143.980 1.00 999.00 ? 571  ASN A OD1 1 
ATOM 4366 N ND2 . ASN A 1 571  ? 117.294 141.788 145.492 1.00 999.00 ? 571  ASN A ND2 1 
ATOM 4367 N N   . ASP A 1 572  ? 116.075 136.419 147.067 1.00 999.00 ? 572  ASP A N   1 
ATOM 4368 C CA  . ASP A 1 572  ? 116.467 135.132 147.622 1.00 999.00 ? 572  ASP A CA  1 
ATOM 4369 C C   . ASP A 1 572  ? 115.477 134.060 147.174 1.00 999.00 ? 572  ASP A C   1 
ATOM 4370 O O   . ASP A 1 572  ? 114.399 134.367 146.668 1.00 999.00 ? 572  ASP A O   1 
ATOM 4371 C CB  . ASP A 1 572  ? 116.559 135.176 149.151 1.00 999.00 ? 572  ASP A CB  1 
ATOM 4372 C CG  . ASP A 1 572  ? 117.833 135.804 149.690 1.00 999.00 ? 572  ASP A CG  1 
ATOM 4373 O OD1 . ASP A 1 572  ? 118.619 136.340 148.883 1.00 999.00 ? 572  ASP A OD1 1 
ATOM 4374 O OD2 . ASP A 1 572  ? 118.042 135.730 150.915 1.00 999.00 ? 572  ASP A OD2 1 
ATOM 4375 N N   . TYR A 1 573  ? 115.865 132.796 147.380 1.00 981.62 ? 573  TYR A N   1 
ATOM 4376 C CA  . TYR A 1 573  ? 115.060 131.660 146.966 1.00 924.17 ? 573  TYR A CA  1 
ATOM 4377 C C   . TYR A 1 573  ? 114.847 130.727 148.157 1.00 872.84 ? 573  TYR A C   1 
ATOM 4378 O O   . TYR A 1 573  ? 115.490 130.876 149.195 1.00 863.42 ? 573  TYR A O   1 
ATOM 4379 C CB  . TYR A 1 573  ? 115.716 130.970 145.766 1.00 918.94 ? 573  TYR A CB  1 
ATOM 4380 C CG  . TYR A 1 573  ? 115.835 131.854 144.550 1.00 919.65 ? 573  TYR A CG  1 
ATOM 4381 C CD1 . TYR A 1 573  ? 116.847 132.796 144.436 1.00 921.80 ? 573  TYR A CD1 1 
ATOM 4382 C CD2 . TYR A 1 573  ? 114.905 131.781 143.526 1.00 914.94 ? 573  TYR A CD2 1 
ATOM 4383 C CE1 . TYR A 1 573  ? 116.942 133.626 143.331 1.00 920.91 ? 573  TYR A CE1 1 
ATOM 4384 C CE2 . TYR A 1 573  ? 114.990 132.597 142.410 1.00 915.62 ? 573  TYR A CE2 1 
ATOM 4385 C CZ  . TYR A 1 573  ? 116.010 133.527 142.313 1.00 918.14 ? 573  TYR A CZ  1 
ATOM 4386 O OH  . TYR A 1 573  ? 116.103 134.338 141.208 1.00 916.22 ? 573  TYR A OH  1 
ATOM 4387 N N   . THR A 1 574  ? 113.908 129.787 147.997 1.00 828.31 ? 574  THR A N   1 
ATOM 4388 C CA  . THR A 1 574  ? 113.588 128.815 149.029 1.00 797.01 ? 574  THR A CA  1 
ATOM 4389 C C   . THR A 1 574  ? 113.612 127.415 148.422 1.00 776.67 ? 574  THR A C   1 
ATOM 4390 O O   . THR A 1 574  ? 112.789 127.092 147.567 1.00 770.52 ? 574  THR A O   1 
ATOM 4391 C CB  . THR A 1 574  ? 112.228 129.108 149.678 1.00 786.82 ? 574  THR A CB  1 
ATOM 4392 O OG1 . THR A 1 574  ? 112.230 130.452 150.160 1.00 781.03 ? 574  THR A OG1 1 
ATOM 4393 C CG2 . THR A 1 574  ? 111.907 128.166 150.818 1.00 784.70 ? 574  THR A CG2 1 
ATOM 4394 N N   . LEU A 1 575  ? 114.582 126.607 148.864 1.00 754.49 ? 575  LEU A N   1 
ATOM 4395 C CA  . LEU A 1 575  ? 114.620 125.186 148.560 1.00 735.09 ? 575  LEU A CA  1 
ATOM 4396 C C   . LEU A 1 575  ? 113.664 124.465 149.506 1.00 739.54 ? 575  LEU A C   1 
ATOM 4397 O O   . LEU A 1 575  ? 113.801 124.582 150.721 1.00 744.03 ? 575  LEU A O   1 
ATOM 4398 C CB  . LEU A 1 575  ? 116.062 124.689 148.724 1.00 714.50 ? 575  LEU A CB  1 
ATOM 4399 C CG  . LEU A 1 575  ? 116.269 123.175 148.669 1.00 698.36 ? 575  LEU A CG  1 
ATOM 4400 C CD1 . LEU A 1 575  ? 115.969 122.631 147.281 1.00 691.87 ? 575  LEU A CD1 1 
ATOM 4401 C CD2 . LEU A 1 575  ? 117.685 122.811 149.089 1.00 693.11 ? 575  LEU A CD2 1 
ATOM 4402 N N   . SER A 1 576  ? 112.686 123.749 148.934 1.00 736.23 ? 576  SER A N   1 
ATOM 4403 C CA  . SER A 1 576  ? 111.756 122.936 149.702 1.00 729.56 ? 576  SER A CA  1 
ATOM 4404 C C   . SER A 1 576  ? 111.979 121.470 149.340 1.00 708.24 ? 576  SER A C   1 
ATOM 4405 O O   . SER A 1 576  ? 112.036 121.145 148.157 1.00 702.19 ? 576  SER A O   1 
ATOM 4406 C CB  . SER A 1 576  ? 110.327 123.348 149.441 1.00 734.16 ? 576  SER A CB  1 
ATOM 4407 O OG  . SER A 1 576  ? 110.180 124.759 149.507 1.00 736.34 ? 576  SER A OG  1 
ATOM 4408 N N   . PHE A 1 577  ? 112.113 120.595 150.347 1.00 679.46 ? 577  PHE A N   1 
ATOM 4409 C CA  . PHE A 1 577  ? 112.431 119.198 150.085 1.00 651.72 ? 577  PHE A CA  1 
ATOM 4410 C C   . PHE A 1 577  ? 111.731 118.260 151.069 1.00 659.51 ? 577  PHE A C   1 
ATOM 4411 O O   . PHE A 1 577  ? 111.416 118.634 152.198 1.00 668.23 ? 577  PHE A O   1 
ATOM 4412 C CB  . PHE A 1 577  ? 113.945 118.970 150.102 1.00 618.73 ? 577  PHE A CB  1 
ATOM 4413 C CG  . PHE A 1 577  ? 114.633 119.323 151.396 1.00 590.51 ? 577  PHE A CG  1 
ATOM 4414 C CD1 . PHE A 1 577  ? 115.038 120.623 151.657 1.00 578.29 ? 577  PHE A CD1 1 
ATOM 4415 C CD2 . PHE A 1 577  ? 114.859 118.356 152.363 1.00 577.24 ? 577  PHE A CD2 1 
ATOM 4416 C CE1 . PHE A 1 577  ? 115.669 120.944 152.849 1.00 573.39 ? 577  PHE A CE1 1 
ATOM 4417 C CE2 . PHE A 1 577  ? 115.488 118.679 153.556 1.00 573.78 ? 577  PHE A CE2 1 
ATOM 4418 C CZ  . PHE A 1 577  ? 115.891 119.972 153.796 1.00 573.25 ? 577  PHE A CZ  1 
ATOM 4419 N N   . TRP A 1 578  ? 111.517 117.021 150.607 1.00 654.24 ? 578  TRP A N   1 
ATOM 4420 C CA  . TRP A 1 578  ? 110.869 115.970 151.375 1.00 647.11 ? 578  TRP A CA  1 
ATOM 4421 C C   . TRP A 1 578  ? 111.885 115.308 152.301 1.00 670.21 ? 578  TRP A C   1 
ATOM 4422 O O   . TRP A 1 578  ? 112.983 114.971 151.864 1.00 665.86 ? 578  TRP A O   1 
ATOM 4423 C CB  . TRP A 1 578  ? 110.255 114.939 150.419 1.00 621.47 ? 578  TRP A CB  1 
ATOM 4424 C CG  . TRP A 1 578  ? 109.270 114.007 151.054 1.00 593.28 ? 578  TRP A CG  1 
ATOM 4425 C CD1 . TRP A 1 578  ? 109.451 112.687 151.350 1.00 572.66 ? 578  TRP A CD1 1 
ATOM 4426 C CD2 . TRP A 1 578  ? 107.918 114.319 151.433 1.00 586.43 ? 578  TRP A CD2 1 
ATOM 4427 N NE1 . TRP A 1 578  ? 108.314 112.163 151.905 1.00 570.62 ? 578  TRP A NE1 1 
ATOM 4428 C CE2 . TRP A 1 578  ? 107.355 113.140 151.967 1.00 578.68 ? 578  TRP A CE2 1 
ATOM 4429 C CE3 . TRP A 1 578  ? 107.133 115.477 151.379 1.00 591.12 ? 578  TRP A CE3 1 
ATOM 4430 C CZ2 . TRP A 1 578  ? 106.044 113.093 152.442 1.00 583.83 ? 578  TRP A CZ2 1 
ATOM 4431 C CZ3 . TRP A 1 578  ? 105.840 115.429 151.851 1.00 588.83 ? 578  TRP A CZ3 1 
ATOM 4432 C CH2 . TRP A 1 578  ? 105.304 114.252 152.375 1.00 587.85 ? 578  TRP A CH2 1 
ATOM 4433 N N   . ARG A 1 579  ? 111.506 115.113 153.570 1.00 701.31 ? 579  ARG A N   1 
ATOM 4434 C CA  . ARG A 1 579  ? 112.321 114.359 154.511 1.00 731.78 ? 579  ARG A CA  1 
ATOM 4435 C C   . ARG A 1 579  ? 111.425 113.700 155.557 1.00 724.30 ? 579  ARG A C   1 
ATOM 4436 O O   . ARG A 1 579  ? 110.715 114.388 156.287 1.00 723.19 ? 579  ARG A O   1 
ATOM 4437 C CB  . ARG A 1 579  ? 113.352 115.265 155.193 1.00 767.39 ? 579  ARG A CB  1 
ATOM 4438 C CG  . ARG A 1 579  ? 114.236 114.539 156.198 1.00 797.57 ? 579  ARG A CG  1 
ATOM 4439 C CD  . ARG A 1 579  ? 115.247 115.449 156.870 1.00 823.59 ? 579  ARG A CD  1 
ATOM 4440 N NE  . ARG A 1 579  ? 115.877 114.797 158.013 1.00 848.20 ? 579  ARG A NE  1 
ATOM 4441 C CZ  . ARG A 1 579  ? 116.180 115.387 159.168 1.00 874.40 ? 579  ARG A CZ  1 
ATOM 4442 N NH1 . ARG A 1 579  ? 116.052 116.694 159.314 1.00 882.97 ? 579  ARG A NH1 1 
ATOM 4443 N NH2 . ARG A 1 579  ? 116.654 114.664 160.169 1.00 882.16 ? 579  ARG A NH2 1 
ATOM 4444 N N   . SER A 1 580  ? 111.472 112.363 155.608 1.00 720.47 ? 580  SER A N   1 
ATOM 4445 C CA  . SER A 1 580  ? 110.841 111.576 156.657 1.00 722.25 ? 580  SER A CA  1 
ATOM 4446 C C   . SER A 1 580  ? 109.359 111.924 156.792 1.00 720.96 ? 580  SER A C   1 
ATOM 4447 O O   . SER A 1 580  ? 108.844 112.048 157.903 1.00 724.55 ? 580  SER A O   1 
ATOM 4448 C CB  . SER A 1 580  ? 111.575 111.746 157.966 1.00 726.84 ? 580  SER A CB  1 
ATOM 4449 O OG  . SER A 1 580  ? 112.950 111.423 157.819 1.00 728.76 ? 580  SER A OG  1 
ATOM 4450 N N   . GLY A 1 581  ? 108.681 112.080 155.648 1.00 718.77 ? 581  GLY A N   1 
ATOM 4451 C CA  . GLY A 1 581  ? 107.237 112.248 155.614 1.00 722.52 ? 581  GLY A CA  1 
ATOM 4452 C C   . GLY A 1 581  ? 106.782 113.696 155.797 1.00 731.09 ? 581  GLY A C   1 
ATOM 4453 O O   . GLY A 1 581  ? 105.582 113.947 155.892 1.00 732.20 ? 581  GLY A O   1 
ATOM 4454 N N   . ARG A 1 582  ? 107.732 114.642 155.835 1.00 742.23 ? 582  ARG A N   1 
ATOM 4455 C CA  . ARG A 1 582  ? 107.417 116.050 156.037 1.00 754.97 ? 582  ARG A CA  1 
ATOM 4456 C C   . ARG A 1 582  ? 108.232 116.909 155.073 1.00 744.38 ? 582  ARG A C   1 
ATOM 4457 O O   . ARG A 1 582  ? 109.285 116.492 154.595 1.00 737.53 ? 582  ARG A O   1 
ATOM 4458 C CB  . ARG A 1 582  ? 107.697 116.465 157.485 1.00 777.61 ? 582  ARG A CB  1 
ATOM 4459 C CG  . ARG A 1 582  ? 106.815 115.776 158.516 1.00 800.10 ? 582  ARG A CG  1 
ATOM 4460 C CD  . ARG A 1 582  ? 107.062 116.293 159.921 1.00 819.23 ? 582  ARG A CD  1 
ATOM 4461 N NE  . ARG A 1 582  ? 106.206 115.650 160.910 1.00 835.42 ? 582  ARG A NE  1 
ATOM 4462 C CZ  . ARG A 1 582  ? 106.204 115.937 162.208 1.00 849.18 ? 582  ARG A CZ  1 
ATOM 4463 N NH1 . ARG A 1 582  ? 107.016 116.865 162.684 1.00 852.87 ? 582  ARG A NH1 1 
ATOM 4464 N NH2 . ARG A 1 582  ? 105.390 115.294 163.027 1.00 853.25 ? 582  ARG A NH2 1 
ATOM 4465 N N   . VAL A 1 583  ? 107.729 118.119 154.801 1.00 741.61 ? 583  VAL A N   1 
ATOM 4466 C CA  . VAL A 1 583  ? 108.407 119.060 153.925 1.00 741.04 ? 583  VAL A CA  1 
ATOM 4467 C C   . VAL A 1 583  ? 109.284 119.974 154.779 1.00 741.05 ? 583  VAL A C   1 
ATOM 4468 O O   . VAL A 1 583  ? 108.836 120.489 155.802 1.00 741.96 ? 583  VAL A O   1 
ATOM 4469 C CB  . VAL A 1 583  ? 107.407 119.870 153.076 1.00 737.26 ? 583  VAL A CB  1 
ATOM 4470 C CG1 . VAL A 1 583  ? 108.112 120.888 152.192 1.00 737.62 ? 583  VAL A CG1 1 
ATOM 4471 C CG2 . VAL A 1 583  ? 106.513 118.969 152.236 1.00 731.93 ? 583  VAL A CG2 1 
ATOM 4472 N N   . GLN A 1 584  ? 110.537 120.153 154.341 1.00 739.08 ? 584  GLN A N   1 
ATOM 4473 C CA  . GLN A 1 584  ? 111.479 121.075 154.958 1.00 736.24 ? 584  GLN A CA  1 
ATOM 4474 C C   . GLN A 1 584  ? 111.757 122.216 153.983 1.00 746.69 ? 584  GLN A C   1 
ATOM 4475 O O   . GLN A 1 584  ? 111.646 122.031 152.773 1.00 751.68 ? 584  GLN A O   1 
ATOM 4476 C CB  . GLN A 1 584  ? 112.776 120.345 155.315 1.00 726.63 ? 584  GLN A CB  1 
ATOM 4477 C CG  . GLN A 1 584  ? 112.595 119.222 156.329 1.00 725.72 ? 584  GLN A CG  1 
ATOM 4478 C CD  . GLN A 1 584  ? 112.243 119.720 157.710 1.00 727.43 ? 584  GLN A CD  1 
ATOM 4479 O OE1 . GLN A 1 584  ? 112.309 120.912 158.004 1.00 727.13 ? 584  GLN A OE1 1 
ATOM 4480 N NE2 . GLN A 1 584  ? 111.880 118.796 158.585 1.00 730.00 ? 584  GLN A NE2 1 
ATOM 4481 N N   . HIS A 1 585  ? 112.114 123.393 154.517 1.00 753.92 ? 585  HIS A N   1 
ATOM 4482 C CA  . HIS A 1 585  ? 112.414 124.554 153.693 1.00 760.31 ? 585  HIS A CA  1 
ATOM 4483 C C   . HIS A 1 585  ? 113.721 125.200 154.151 1.00 740.57 ? 585  HIS A C   1 
ATOM 4484 O O   . HIS A 1 585  ? 113.893 125.481 155.336 1.00 732.79 ? 585  HIS A O   1 
ATOM 4485 C CB  . HIS A 1 585  ? 111.278 125.584 153.732 1.00 780.95 ? 585  HIS A CB  1 
ATOM 4486 C CG  . HIS A 1 585  ? 109.923 125.045 153.405 1.00 799.98 ? 585  HIS A CG  1 
ATOM 4487 N ND1 . HIS A 1 585  ? 109.308 125.219 152.183 1.00 804.97 ? 585  HIS A ND1 1 
ATOM 4488 C CD2 . HIS A 1 585  ? 109.071 124.328 154.147 1.00 809.48 ? 585  HIS A CD2 1 
ATOM 4489 C CE1 . HIS A 1 585  ? 108.122 124.628 152.203 1.00 805.08 ? 585  HIS A CE1 1 
ATOM 4490 N NE2 . HIS A 1 585  ? 107.955 124.086 153.390 1.00 807.61 ? 585  HIS A NE2 1 
ATOM 4491 N N   . CYS A 1 586  ? 114.623 125.443 153.190 1.00 729.14 ? 586  CYS A N   1 
ATOM 4492 C CA  . CYS A 1 586  ? 115.874 126.144 153.434 1.00 722.31 ? 586  CYS A CA  1 
ATOM 4493 C C   . CYS A 1 586  ? 115.972 127.363 152.519 1.00 738.70 ? 586  CYS A C   1 
ATOM 4494 O O   . CYS A 1 586  ? 115.682 127.276 151.327 1.00 741.12 ? 586  CYS A O   1 
ATOM 4495 C CB  . CYS A 1 586  ? 117.073 125.231 153.205 1.00 706.30 ? 586  CYS A CB  1 
ATOM 4496 S SG  . CYS A 1 586  ? 117.205 123.896 154.423 1.00 684.57 ? 586  CYS A SG  1 
ATOM 4497 N N   . ARG A 1 587  ? 116.393 128.495 153.096 1.00 757.31 ? 587  ARG A N   1 
ATOM 4498 C CA  . ARG A 1 587  ? 116.543 129.742 152.364 1.00 774.15 ? 587  ARG A CA  1 
ATOM 4499 C C   . ARG A 1 587  ? 117.865 129.722 151.601 1.00 760.84 ? 587  ARG A C   1 
ATOM 4500 O O   . ARG A 1 587  ? 118.927 129.596 152.207 1.00 759.05 ? 587  ARG A O   1 
ATOM 4501 C CB  . ARG A 1 587  ? 116.493 130.929 153.333 1.00 802.71 ? 587  ARG A CB  1 
ATOM 4502 C CG  . ARG A 1 587  ? 116.719 132.291 152.690 1.00 831.52 ? 587  ARG A CG  1 
ATOM 4503 C CD  . ARG A 1 587  ? 116.733 133.402 153.724 1.00 860.15 ? 587  ARG A CD  1 
ATOM 4504 N NE  . ARG A 1 587  ? 117.089 134.697 153.159 1.00 888.08 ? 587  ARG A NE  1 
ATOM 4505 C CZ  . ARG A 1 587  ? 117.300 135.804 153.866 1.00 913.13 ? 587  ARG A CZ  1 
ATOM 4506 N NH1 . ARG A 1 587  ? 117.132 135.806 155.177 1.00 919.36 ? 587  ARG A NH1 1 
ATOM 4507 N NH2 . ARG A 1 587  ? 117.668 136.916 153.252 1.00 922.76 ? 587  ARG A NH2 1 
ATOM 4508 N N   . ILE A 1 588  ? 117.779 129.834 150.269 1.00 752.39 ? 588  ILE A N   1 
ATOM 4509 C CA  . ILE A 1 588  ? 118.936 130.099 149.429 1.00 749.57 ? 588  ILE A CA  1 
ATOM 4510 C C   . ILE A 1 588  ? 119.189 131.605 149.451 1.00 794.65 ? 588  ILE A C   1 
ATOM 4511 O O   . ILE A 1 588  ? 118.390 132.375 148.922 1.00 800.93 ? 588  ILE A O   1 
ATOM 4512 C CB  . ILE A 1 588  ? 118.717 129.581 147.992 1.00 714.09 ? 588  ILE A CB  1 
ATOM 4513 C CG1 . ILE A 1 588  ? 118.414 128.079 147.959 1.00 695.85 ? 588  ILE A CG1 1 
ATOM 4514 C CG2 . ILE A 1 588  ? 119.904 129.937 147.106 1.00 707.10 ? 588  ILE A CG2 1 
ATOM 4515 C CD1 . ILE A 1 588  ? 117.882 127.588 146.631 1.00 685.92 ? 588  ILE A CD1 1 
ATOM 4516 N N   . ARG A 1 589  ? 120.303 132.007 150.075 1.00 854.92 ? 589  ARG A N   1 
ATOM 4517 C CA  . ARG A 1 589  ? 120.641 133.410 150.246 1.00 914.21 ? 589  ARG A CA  1 
ATOM 4518 C C   . ARG A 1 589  ? 121.405 133.907 149.021 1.00 982.65 ? 589  ARG A C   1 
ATOM 4519 O O   . ARG A 1 589  ? 122.165 133.152 148.417 1.00 984.97 ? 589  ARG A O   1 
ATOM 4520 C CB  . ARG A 1 589  ? 121.497 133.599 151.502 1.00 917.28 ? 589  ARG A CB  1 
ATOM 4521 C CG  . ARG A 1 589  ? 120.812 133.218 152.806 1.00 921.93 ? 589  ARG A CG  1 
ATOM 4522 C CD  . ARG A 1 589  ? 121.811 133.165 153.947 1.00 930.33 ? 589  ARG A CD  1 
ATOM 4523 N NE  . ARG A 1 589  ? 121.205 132.841 155.231 1.00 938.52 ? 589  ARG A NE  1 
ATOM 4524 C CZ  . ARG A 1 589  ? 121.885 132.635 156.355 1.00 947.02 ? 589  ARG A CZ  1 
ATOM 4525 N NH1 . ARG A 1 589  ? 123.205 132.697 156.353 1.00 950.24 ? 589  ARG A NH1 1 
ATOM 4526 N NH2 . ARG A 1 589  ? 121.242 132.361 157.477 1.00 949.49 ? 589  ARG A NH2 1 
ATOM 4527 N N   . SER A 1 590  ? 121.198 135.186 148.678 1.00 999.00 ? 590  SER A N   1 
ATOM 4528 C CA  . SER A 1 590  ? 121.960 135.847 147.630 1.00 999.00 ? 590  SER A CA  1 
ATOM 4529 C C   . SER A 1 590  ? 122.907 136.868 148.257 1.00 999.00 ? 590  SER A C   1 
ATOM 4530 O O   . SER A 1 590  ? 122.601 137.438 149.304 1.00 999.00 ? 590  SER A O   1 
ATOM 4531 C CB  . SER A 1 590  ? 121.050 136.484 146.603 1.00 999.00 ? 590  SER A CB  1 
ATOM 4532 O OG  . SER A 1 590  ? 120.229 137.487 147.186 1.00 999.00 ? 590  SER A OG  1 
ATOM 4533 N N   . THR A 1 591  ? 124.070 137.069 147.620 1.00 999.00 ? 591  THR A N   1 
ATOM 4534 C CA  . THR A 1 591  ? 125.023 138.090 148.030 1.00 999.00 ? 591  THR A CA  1 
ATOM 4535 C C   . THR A 1 591  ? 125.769 138.607 146.802 1.00 999.00 ? 591  THR A C   1 
ATOM 4536 O O   . THR A 1 591  ? 125.958 137.874 145.834 1.00 999.00 ? 591  THR A O   1 
ATOM 4537 C CB  . THR A 1 591  ? 126.010 137.563 149.083 1.00 999.00 ? 591  THR A CB  1 
ATOM 4538 O OG1 . THR A 1 591  ? 126.775 138.669 149.564 1.00 999.00 ? 591  THR A OG1 1 
ATOM 4539 C CG2 . THR A 1 591  ? 126.942 136.495 148.553 1.00 999.00 ? 591  THR A CG2 1 
ATOM 4540 N N   . MET A 1 592  ? 126.182 139.878 146.857 1.00 999.00 ? 592  MET A N   1 
ATOM 4541 C CA  . MET A 1 592  ? 126.990 140.480 145.809 1.00 999.00 ? 592  MET A CA  1 
ATOM 4542 C C   . MET A 1 592  ? 128.452 140.469 146.249 1.00 999.00 ? 592  MET A C   1 
ATOM 4543 O O   . MET A 1 592  ? 128.797 141.078 147.260 1.00 999.00 ? 592  MET A O   1 
ATOM 4544 C CB  . MET A 1 592  ? 126.546 141.921 145.535 1.00 999.00 ? 592  MET A CB  1 
ATOM 4545 C CG  . MET A 1 592  ? 125.414 142.025 144.528 1.00 999.00 ? 592  MET A CG  1 
ATOM 4546 S SD  . MET A 1 592  ? 124.893 143.736 144.238 1.00 999.00 ? 592  MET A SD  1 
ATOM 4547 C CE  . MET A 1 592  ? 123.184 143.488 143.756 1.00 999.00 ? 592  MET A CE  1 
ATOM 4548 N N   . GLU A 1 593  ? 129.295 139.759 145.488 1.00 999.00 ? 593  GLU A N   1 
ATOM 4549 C CA  . GLU A 1 593  ? 130.727 139.710 145.739 1.00 999.00 ? 593  GLU A CA  1 
ATOM 4550 C C   . GLU A 1 593  ? 131.458 140.090 144.453 1.00 999.00 ? 593  GLU A C   1 
ATOM 4551 O O   . GLU A 1 593  ? 131.369 139.381 143.452 1.00 999.00 ? 593  GLU A O   1 
ATOM 4552 C CB  . GLU A 1 593  ? 131.134 138.318 146.231 1.00 999.00 ? 593  GLU A CB  1 
ATOM 4553 C CG  . GLU A 1 593  ? 132.520 138.269 146.855 1.00 999.00 ? 593  GLU A CG  1 
ATOM 4554 C CD  . GLU A 1 593  ? 132.993 136.888 147.279 1.00 999.00 ? 593  GLU A CD  1 
ATOM 4555 O OE1 . GLU A 1 593  ? 134.127 136.785 147.786 1.00 999.00 ? 593  GLU A OE1 1 
ATOM 4556 O OE2 . GLU A 1 593  ? 132.231 135.917 147.098 1.00 999.00 ? 593  GLU A OE2 1 
ATOM 4557 N N   . GLY A 1 594  ? 132.151 141.237 144.486 1.00 999.00 ? 594  GLY A N   1 
ATOM 4558 C CA  . GLY A 1 594  ? 132.946 141.707 143.362 1.00 999.00 ? 594  GLY A CA  1 
ATOM 4559 C C   . GLY A 1 594  ? 132.095 142.122 142.163 1.00 999.00 ? 594  GLY A C   1 
ATOM 4560 O O   . GLY A 1 594  ? 132.580 142.121 141.033 1.00 999.00 ? 594  GLY A O   1 
ATOM 4561 N N   . GLY A 1 595  ? 130.828 142.478 142.419 1.00 999.00 ? 595  GLY A N   1 
ATOM 4562 C CA  . GLY A 1 595  ? 129.906 142.887 141.370 1.00 999.00 ? 595  GLY A CA  1 
ATOM 4563 C C   . GLY A 1 595  ? 129.090 141.725 140.803 1.00 999.00 ? 595  GLY A C   1 
ATOM 4564 O O   . GLY A 1 595  ? 128.157 141.953 140.035 1.00 999.00 ? 595  GLY A O   1 
ATOM 4565 N N   . THR A 1 596  ? 129.444 140.488 141.186 1.00 999.00 ? 596  THR A N   1 
ATOM 4566 C CA  . THR A 1 596  ? 128.780 139.292 140.691 1.00 999.00 ? 596  THR A CA  1 
ATOM 4567 C C   . THR A 1 596  ? 127.860 138.738 141.778 1.00 999.00 ? 596  THR A C   1 
ATOM 4568 O O   . THR A 1 596  ? 128.266 138.600 142.931 1.00 999.00 ? 596  THR A O   1 
ATOM 4569 C CB  . THR A 1 596  ? 129.799 138.233 140.248 1.00 999.00 ? 596  THR A CB  1 
ATOM 4570 O OG1 . THR A 1 596  ? 130.814 138.869 139.470 1.00 999.00 ? 596  THR A OG1 1 
ATOM 4571 C CG2 . THR A 1 596  ? 129.176 137.111 139.445 1.00 999.00 ? 596  THR A CG2 1 
ATOM 4572 N N   . LEU A 1 597  ? 126.618 138.421 141.396 1.00 999.00 ? 597  LEU A N   1 
ATOM 4573 C CA  . LEU A 1 597  ? 125.640 137.876 142.323 1.00 999.00 ? 597  LEU A CA  1 
ATOM 4574 C C   . LEU A 1 597  ? 125.963 136.402 142.564 1.00 999.00 ? 597  LEU A C   1 
ATOM 4575 O O   . LEU A 1 597  ? 126.168 135.651 141.612 1.00 999.00 ? 597  LEU A O   1 
ATOM 4576 C CB  . LEU A 1 597  ? 124.238 138.065 141.733 1.00 999.00 ? 597  LEU A CB  1 
ATOM 4577 C CG  . LEU A 1 597  ? 123.074 137.919 142.714 1.00 999.00 ? 597  LEU A CG  1 
ATOM 4578 C CD1 . LEU A 1 597  ? 123.018 139.098 143.675 1.00 999.00 ? 597  LEU A CD1 1 
ATOM 4579 C CD2 . LEU A 1 597  ? 121.752 137.779 141.973 1.00 999.00 ? 597  LEU A CD2 1 
ATOM 4580 N N   . LYS A 1 598  ? 126.029 136.012 143.845 1.00 999.00 ? 598  LYS A N   1 
ATOM 4581 C CA  . LYS A 1 598  ? 126.330 134.644 144.240 1.00 999.00 ? 598  LYS A CA  1 
ATOM 4582 C C   . LYS A 1 598  ? 125.231 134.116 145.159 1.00 999.00 ? 598  LYS A C   1 
ATOM 4583 O O   . LYS A 1 598  ? 124.603 134.886 145.883 1.00 999.00 ? 598  LYS A O   1 
ATOM 4584 C CB  . LYS A 1 598  ? 127.676 134.567 144.969 1.00 999.00 ? 598  LYS A CB  1 
ATOM 4585 C CG  . LYS A 1 598  ? 128.906 134.863 144.122 1.00 999.00 ? 598  LYS A CG  1 
ATOM 4586 C CD  . LYS A 1 598  ? 130.197 134.599 144.867 1.00 999.00 ? 598  LYS A CD  1 
ATOM 4587 C CE  . LYS A 1 598  ? 131.439 134.892 144.053 1.00 999.00 ? 598  LYS A CE  1 
ATOM 4588 N NZ  . LYS A 1 598  ? 132.674 134.535 144.792 1.00 999.00 ? 598  LYS A NZ  1 
ATOM 4589 N N   . TYR A 1 599  ? 125.049 132.788 145.141 1.00 999.00 ? 599  TYR A N   1 
ATOM 4590 C CA  . TYR A 1 599  ? 124.012 132.110 145.904 1.00 999.00 ? 599  TYR A CA  1 
ATOM 4591 C C   . TYR A 1 599  ? 124.644 131.087 146.844 1.00 999.00 ? 599  TYR A C   1 
ATOM 4592 O O   . TYR A 1 599  ? 125.639 130.454 146.493 1.00 999.00 ? 599  TYR A O   1 
ATOM 4593 C CB  . TYR A 1 599  ? 123.034 131.417 144.953 1.00 999.00 ? 599  TYR A CB  1 
ATOM 4594 C CG  . TYR A 1 599  ? 122.348 132.345 143.985 1.00 999.00 ? 599  TYR A CG  1 
ATOM 4595 C CD1 . TYR A 1 599  ? 121.235 133.079 144.364 1.00 999.00 ? 599  TYR A CD1 1 
ATOM 4596 C CD2 . TYR A 1 599  ? 122.833 132.520 142.699 1.00 999.00 ? 599  TYR A CD2 1 
ATOM 4597 C CE1 . TYR A 1 599  ? 120.602 133.939 143.481 1.00 999.00 ? 599  TYR A CE1 1 
ATOM 4598 C CE2 . TYR A 1 599  ? 122.214 133.378 141.804 1.00 999.00 ? 599  TYR A CE2 1 
ATOM 4599 C CZ  . TYR A 1 599  ? 121.094 134.091 142.196 1.00 999.00 ? 599  TYR A CZ  1 
ATOM 4600 O OH  . TYR A 1 599  ? 120.475 134.945 141.317 1.00 999.00 ? 599  TYR A OH  1 
ATOM 4601 N N   . TYR A 1 600  ? 124.047 130.912 148.031 1.00 999.00 ? 600  TYR A N   1 
ATOM 4602 C CA  . TYR A 1 600  ? 124.576 129.976 149.012 1.00 999.00 ? 600  TYR A CA  1 
ATOM 4603 C C   . TYR A 1 600  ? 123.473 129.493 149.954 1.00 999.00 ? 600  TYR A C   1 
ATOM 4604 O O   . TYR A 1 600  ? 122.508 130.208 150.215 1.00 999.00 ? 600  TYR A O   1 
ATOM 4605 C CB  . TYR A 1 600  ? 125.741 130.610 149.780 1.00 999.00 ? 600  TYR A CB  1 
ATOM 4606 C CG  . TYR A 1 600  ? 125.410 131.859 150.560 1.00 999.00 ? 600  TYR A CG  1 
ATOM 4607 C CD1 . TYR A 1 600  ? 125.237 133.081 149.929 1.00 999.00 ? 600  TYR A CD1 1 
ATOM 4608 C CD2 . TYR A 1 600  ? 125.276 131.821 151.939 1.00 999.00 ? 600  TYR A CD2 1 
ATOM 4609 C CE1 . TYR A 1 600  ? 124.935 134.229 150.645 1.00 999.00 ? 600  TYR A CE1 1 
ATOM 4610 C CE2 . TYR A 1 600  ? 124.977 132.960 152.670 1.00 999.00 ? 600  TYR A CE2 1 
ATOM 4611 C CZ  . TYR A 1 600  ? 124.805 134.170 152.021 1.00 999.00 ? 600  TYR A CZ  1 
ATOM 4612 O OH  . TYR A 1 600  ? 124.505 135.301 152.741 1.00 999.00 ? 600  TYR A OH  1 
ATOM 4613 N N   . LEU A 1 601  ? 123.633 128.252 150.436 1.00 999.00 ? 601  LEU A N   1 
ATOM 4614 C CA  . LEU A 1 601  ? 122.805 127.691 151.495 1.00 999.00 ? 601  LEU A CA  1 
ATOM 4615 C C   . LEU A 1 601  ? 123.568 127.738 152.818 1.00 999.00 ? 601  LEU A C   1 
ATOM 4616 O O   . LEU A 1 601  ? 122.980 128.020 153.860 1.00 999.00 ? 601  LEU A O   1 
ATOM 4617 C CB  . LEU A 1 601  ? 122.420 126.251 151.132 1.00 999.00 ? 601  LEU A CB  1 
ATOM 4618 C CG  . LEU A 1 601  ? 121.203 126.090 150.220 1.00 998.64 ? 601  LEU A CG  1 
ATOM 4619 C CD1 . LEU A 1 601  ? 120.986 124.627 149.854 1.00 997.07 ? 601  LEU A CD1 1 
ATOM 4620 C CD2 . LEU A 1 601  ? 119.950 126.657 150.875 1.00 991.10 ? 601  LEU A CD2 1 
ATOM 4621 N N   . THR A 1 602  ? 124.873 127.434 152.762 1.00 998.48 ? 602  THR A N   1 
ATOM 4622 C CA  . THR A 1 602  ? 125.768 127.568 153.901 1.00 991.35 ? 602  THR A CA  1 
ATOM 4623 C C   . THR A 1 602  ? 126.837 128.609 153.574 1.00 998.62 ? 602  THR A C   1 
ATOM 4624 O O   . THR A 1 602  ? 127.251 128.738 152.425 1.00 997.72 ? 602  THR A O   1 
ATOM 4625 C CB  . THR A 1 602  ? 126.384 126.213 154.277 1.00 979.02 ? 602  THR A CB  1 
ATOM 4626 O OG1 . THR A 1 602  ? 127.103 125.709 153.151 1.00 969.44 ? 602  THR A OG1 1 
ATOM 4627 C CG2 . THR A 1 602  ? 125.346 125.200 154.710 1.00 977.05 ? 602  THR A CG2 1 
ATOM 4628 N N   . ASP A 1 603  ? 127.312 129.317 154.604 1.00 999.00 ? 603  ASP A N   1 
ATOM 4629 C CA  . ASP A 1 603  ? 128.128 130.507 154.417 1.00 999.00 ? 603  ASP A CA  1 
ATOM 4630 C C   . ASP A 1 603  ? 129.503 130.161 153.839 1.00 999.00 ? 603  ASP A C   1 
ATOM 4631 O O   . ASP A 1 603  ? 130.251 131.067 153.476 1.00 999.00 ? 603  ASP A O   1 
ATOM 4632 C CB  . ASP A 1 603  ? 128.273 131.286 155.729 1.00 999.00 ? 603  ASP A CB  1 
ATOM 4633 C CG  . ASP A 1 603  ? 126.947 131.661 156.373 1.00 999.00 ? 603  ASP A CG  1 
ATOM 4634 O OD1 . ASP A 1 603  ? 126.037 132.078 155.632 1.00 999.00 ? 603  ASP A OD1 1 
ATOM 4635 O OD2 . ASP A 1 603  ? 126.840 131.547 157.612 1.00 999.00 ? 603  ASP A OD2 1 
ATOM 4636 N N   . ASN A 1 604  ? 129.825 128.862 153.738 1.00 999.00 ? 604  ASN A N   1 
ATOM 4637 C CA  . ASN A 1 604  ? 131.152 128.411 153.344 1.00 997.56 ? 604  ASN A CA  1 
ATOM 4638 C C   . ASN A 1 604  ? 131.234 128.119 151.843 1.00 975.76 ? 604  ASN A C   1 
ATOM 4639 O O   . ASN A 1 604  ? 132.336 127.975 151.318 1.00 976.57 ? 604  ASN A O   1 
ATOM 4640 C CB  . ASN A 1 604  ? 131.568 127.162 154.128 1.00 999.00 ? 604  ASN A CB  1 
ATOM 4641 C CG  . ASN A 1 604  ? 131.691 127.395 155.620 1.00 999.00 ? 604  ASN A CG  1 
ATOM 4642 O OD1 . ASN A 1 604  ? 131.645 128.530 156.090 1.00 999.00 ? 604  ASN A OD1 1 
ATOM 4643 N ND2 . ASN A 1 604  ? 131.863 126.323 156.375 1.00 999.00 ? 604  ASN A ND2 1 
ATOM 4644 N N   . LEU A 1 605  ? 130.084 128.037 151.157 1.00 950.65 ? 605  LEU A N   1 
ATOM 4645 C CA  . LEU A 1 605  ? 130.033 127.575 149.776 1.00 932.14 ? 605  LEU A CA  1 
ATOM 4646 C C   . LEU A 1 605  ? 129.128 128.482 148.942 1.00 917.32 ? 605  LEU A C   1 
ATOM 4647 O O   . LEU A 1 605  ? 127.907 128.435 149.080 1.00 918.54 ? 605  LEU A O   1 
ATOM 4648 C CB  . LEU A 1 605  ? 129.521 126.130 149.766 1.00 928.49 ? 605  LEU A CB  1 
ATOM 4649 C CG  . LEU A 1 605  ? 130.567 125.046 150.027 1.00 929.77 ? 605  LEU A CG  1 
ATOM 4650 C CD1 . LEU A 1 605  ? 129.898 123.735 150.413 1.00 929.09 ? 605  LEU A CD1 1 
ATOM 4651 C CD2 . LEU A 1 605  ? 131.456 124.835 148.808 1.00 931.58 ? 605  LEU A CD2 1 
ATOM 4652 N N   . THR A 1 606  ? 129.745 129.283 148.060 1.00 899.23 ? 606  THR A N   1 
ATOM 4653 C CA  . THR A 1 606  ? 129.030 130.211 147.193 1.00 883.20 ? 606  THR A CA  1 
ATOM 4654 C C   . THR A 1 606  ? 129.057 129.709 145.750 1.00 851.53 ? 606  THR A C   1 
ATOM 4655 O O   . THR A 1 606  ? 130.082 129.216 145.283 1.00 848.84 ? 606  THR A O   1 
ATOM 4656 C CB  . THR A 1 606  ? 129.636 131.619 147.263 1.00 892.10 ? 606  THR A CB  1 
ATOM 4657 O OG1 . THR A 1 606  ? 130.970 131.564 146.757 1.00 894.27 ? 606  THR A OG1 1 
ATOM 4658 C CG2 . THR A 1 606  ? 129.645 132.191 148.664 1.00 895.03 ? 606  THR A CG2 1 
ATOM 4659 N N   . PHE A 1 607  ? 127.925 129.877 145.051 1.00 816.11 ? 607  PHE A N   1 
ATOM 4660 C CA  . PHE A 1 607  ? 127.768 129.433 143.674 1.00 784.65 ? 607  PHE A CA  1 
ATOM 4661 C C   . PHE A 1 607  ? 127.381 130.614 142.787 1.00 790.43 ? 607  PHE A C   1 
ATOM 4662 O O   . PHE A 1 607  ? 126.740 131.558 143.246 1.00 805.40 ? 607  PHE A O   1 
ATOM 4663 C CB  . PHE A 1 607  ? 126.718 128.323 143.582 1.00 754.11 ? 607  PHE A CB  1 
ATOM 4664 C CG  . PHE A 1 607  ? 127.014 127.114 144.433 1.00 722.69 ? 607  PHE A CG  1 
ATOM 4665 C CD1 . PHE A 1 607  ? 126.641 127.072 145.768 1.00 710.84 ? 607  PHE A CD1 1 
ATOM 4666 C CD2 . PHE A 1 607  ? 127.704 126.034 143.906 1.00 699.98 ? 607  PHE A CD2 1 
ATOM 4667 C CE1 . PHE A 1 607  ? 126.925 125.961 146.548 1.00 697.09 ? 607  PHE A CE1 1 
ATOM 4668 C CE2 . PHE A 1 607  ? 127.991 124.925 144.688 1.00 689.21 ? 607  PHE A CE2 1 
ATOM 4669 C CZ  . PHE A 1 607  ? 127.600 124.890 146.007 1.00 687.97 ? 607  PHE A CZ  1 
ATOM 4670 N N   . SER A 1 608  ? 127.758 130.529 141.505 1.00 788.56 ? 608  SER A N   1 
ATOM 4671 C CA  . SER A 1 608  ? 127.550 131.607 140.550 1.00 786.02 ? 608  SER A CA  1 
ATOM 4672 C C   . SER A 1 608  ? 126.094 131.661 140.086 1.00 775.63 ? 608  SER A C   1 
ATOM 4673 O O   . SER A 1 608  ? 125.645 132.694 139.591 1.00 780.20 ? 608  SER A O   1 
ATOM 4674 C CB  . SER A 1 608  ? 128.489 131.466 139.379 1.00 790.94 ? 608  SER A CB  1 
ATOM 4675 O OG  . SER A 1 608  ? 128.396 130.170 138.807 1.00 794.41 ? 608  SER A OG  1 
ATOM 4676 N N   . SER A 1 609  ? 125.368 130.544 140.233 1.00 761.49 ? 609  SER A N   1 
ATOM 4677 C CA  . SER A 1 609  ? 123.963 130.481 139.861 1.00 750.37 ? 609  SER A CA  1 
ATOM 4678 C C   . SER A 1 609  ? 123.234 129.451 140.722 1.00 744.39 ? 609  SER A C   1 
ATOM 4679 O O   . SER A 1 609  ? 123.862 128.593 141.341 1.00 742.94 ? 609  SER A O   1 
ATOM 4680 C CB  . SER A 1 609  ? 123.802 130.175 138.391 1.00 747.46 ? 609  SER A CB  1 
ATOM 4681 O OG  . SER A 1 609  ? 124.185 128.837 138.099 1.00 745.37 ? 609  SER A OG  1 
ATOM 4682 N N   . ILE A 1 610  ? 121.899 129.548 140.736 1.00 743.27 ? 610  ILE A N   1 
ATOM 4683 C CA  . ILE A 1 610  ? 121.055 128.622 141.476 1.00 745.52 ? 610  ILE A CA  1 
ATOM 4684 C C   . ILE A 1 610  ? 121.205 127.230 140.865 1.00 754.29 ? 610  ILE A C   1 
ATOM 4685 O O   . ILE A 1 610  ? 121.197 126.234 141.585 1.00 769.41 ? 610  ILE A O   1 
ATOM 4686 C CB  . ILE A 1 610  ? 119.582 129.084 141.482 1.00 740.41 ? 610  ILE A CB  1 
ATOM 4687 C CG1 . ILE A 1 610  ? 119.414 130.488 142.073 1.00 742.19 ? 610  ILE A CG1 1 
ATOM 4688 C CG2 . ILE A 1 610  ? 118.704 128.074 142.207 1.00 735.70 ? 610  ILE A CG2 1 
ATOM 4689 C CD1 . ILE A 1 610  ? 118.097 131.136 141.733 1.00 744.45 ? 610  ILE A CD1 1 
ATOM 4690 N N   . TYR A 1 611  ? 121.338 127.179 139.532 1.00 748.57 ? 611  TYR A N   1 
ATOM 4691 C CA  . TYR A 1 611  ? 121.561 125.933 138.817 1.00 742.38 ? 611  TYR A CA  1 
ATOM 4692 C C   . TYR A 1 611  ? 122.772 125.208 139.403 1.00 758.92 ? 611  TYR A C   1 
ATOM 4693 O O   . TYR A 1 611  ? 122.673 124.041 139.772 1.00 765.07 ? 611  TYR A O   1 
ATOM 4694 C CB  . TYR A 1 611  ? 121.756 126.191 137.320 1.00 721.62 ? 611  TYR A CB  1 
ATOM 4695 C CG  . TYR A 1 611  ? 122.010 124.950 136.502 1.00 700.58 ? 611  TYR A CG  1 
ATOM 4696 C CD1 . TYR A 1 611  ? 120.966 124.156 136.051 1.00 689.29 ? 611  TYR A CD1 1 
ATOM 4697 C CD2 . TYR A 1 611  ? 123.303 124.540 136.219 1.00 688.17 ? 611  TYR A CD2 1 
ATOM 4698 C CE1 . TYR A 1 611  ? 121.199 123.007 135.312 1.00 679.97 ? 611  TYR A CE1 1 
ATOM 4699 C CE2 . TYR A 1 611  ? 123.554 123.392 135.484 1.00 679.89 ? 611  TYR A CE2 1 
ATOM 4700 C CZ  . TYR A 1 611  ? 122.498 122.622 135.029 1.00 675.31 ? 611  TYR A CZ  1 
ATOM 4701 O OH  . TYR A 1 611  ? 122.744 121.484 134.301 1.00 666.79 ? 611  TYR A OH  1 
ATOM 4702 N N   . ALA A 1 612  ? 123.904 125.920 139.496 1.00 770.21 ? 612  ALA A N   1 
ATOM 4703 C CA  . ALA A 1 612  ? 125.152 125.350 139.984 1.00 781.86 ? 612  ALA A CA  1 
ATOM 4704 C C   . ALA A 1 612  ? 124.997 124.861 141.423 1.00 806.07 ? 612  ALA A C   1 
ATOM 4705 O O   . ALA A 1 612  ? 125.514 123.801 141.774 1.00 800.91 ? 612  ALA A O   1 
ATOM 4706 C CB  . ALA A 1 612  ? 126.259 126.370 139.870 1.00 776.73 ? 612  ALA A CB  1 
ATOM 4707 N N   . LEU A 1 613  ? 124.289 125.647 142.246 1.00 840.19 ? 613  LEU A N   1 
ATOM 4708 C CA  . LEU A 1 613  ? 124.045 125.314 143.641 1.00 868.59 ? 613  LEU A CA  1 
ATOM 4709 C C   . LEU A 1 613  ? 123.267 124.002 143.745 1.00 873.31 ? 613  LEU A C   1 
ATOM 4710 O O   . LEU A 1 613  ? 123.629 123.135 144.538 1.00 874.72 ? 613  LEU A O   1 
ATOM 4711 C CB  . LEU A 1 613  ? 123.300 126.484 144.299 1.00 889.80 ? 613  LEU A CB  1 
ATOM 4712 C CG  . LEU A 1 613  ? 122.984 126.346 145.790 1.00 905.72 ? 613  LEU A CG  1 
ATOM 4713 C CD1 . LEU A 1 613  ? 122.925 127.713 146.455 1.00 910.68 ? 613  LEU A CD1 1 
ATOM 4714 C CD2 . LEU A 1 613  ? 121.671 125.609 146.017 1.00 912.56 ? 613  LEU A CD2 1 
ATOM 4715 N N   . ILE A 1 614  ? 122.213 123.853 142.932 1.00 868.26 ? 614  ILE A N   1 
ATOM 4716 C CA  . ILE A 1 614  ? 121.334 122.696 143.022 1.00 855.81 ? 614  ILE A CA  1 
ATOM 4717 C C   . ILE A 1 614  ? 122.053 121.448 142.508 1.00 826.25 ? 614  ILE A C   1 
ATOM 4718 O O   . ILE A 1 614  ? 121.956 120.394 143.132 1.00 836.34 ? 614  ILE A O   1 
ATOM 4719 C CB  . ILE A 1 614  ? 119.994 122.958 142.299 1.00 859.03 ? 614  ILE A CB  1 
ATOM 4720 C CG1 . ILE A 1 614  ? 119.158 124.010 143.036 1.00 854.12 ? 614  ILE A CG1 1 
ATOM 4721 C CG2 . ILE A 1 614  ? 119.208 121.669 142.096 1.00 860.12 ? 614  ILE A CG2 1 
ATOM 4722 C CD1 . ILE A 1 614  ? 118.734 123.608 144.435 1.00 852.22 ? 614  ILE A CD1 1 
ATOM 4723 N N   . GLN A 1 615  ? 122.781 121.562 141.389 1.00 777.96 ? 615  GLN A N   1 
ATOM 4724 C CA  . GLN A 1 615  ? 123.503 120.421 140.843 1.00 738.07 ? 615  GLN A CA  1 
ATOM 4725 C C   . GLN A 1 615  ? 124.513 119.907 141.870 1.00 745.41 ? 615  GLN A C   1 
ATOM 4726 O O   . GLN A 1 615  ? 124.678 118.697 142.015 1.00 741.51 ? 615  GLN A O   1 
ATOM 4727 C CB  . GLN A 1 615  ? 124.186 120.777 139.519 1.00 702.91 ? 615  GLN A CB  1 
ATOM 4728 C CG  . GLN A 1 615  ? 123.215 121.105 138.390 1.00 677.58 ? 615  GLN A CG  1 
ATOM 4729 C CD  . GLN A 1 615  ? 122.341 119.943 137.980 1.00 654.43 ? 615  GLN A CD  1 
ATOM 4730 O OE1 . GLN A 1 615  ? 122.595 118.789 138.319 1.00 639.35 ? 615  GLN A OE1 1 
ATOM 4731 N NE2 . GLN A 1 615  ? 121.297 120.244 137.224 1.00 648.61 ? 615  GLN A NE2 1 
ATOM 4732 N N   . HIS A 1 616  ? 125.160 120.828 142.598 1.00 758.93 ? 616  HIS A N   1 
ATOM 4733 C CA  . HIS A 1 616  ? 126.128 120.466 143.622 1.00 771.70 ? 616  HIS A CA  1 
ATOM 4734 C C   . HIS A 1 616  ? 125.479 119.600 144.703 1.00 799.45 ? 616  HIS A C   1 
ATOM 4735 O O   . HIS A 1 616  ? 126.056 118.592 145.101 1.00 801.89 ? 616  HIS A O   1 
ATOM 4736 C CB  . HIS A 1 616  ? 126.776 121.709 144.243 1.00 762.69 ? 616  HIS A CB  1 
ATOM 4737 C CG  . HIS A 1 616  ? 127.671 121.388 145.394 1.00 759.74 ? 616  HIS A CG  1 
ATOM 4738 N ND1 . HIS A 1 616  ? 128.966 120.938 145.253 1.00 762.13 ? 616  HIS A ND1 1 
ATOM 4739 C CD2 . HIS A 1 616  ? 127.442 121.453 146.711 1.00 758.77 ? 616  HIS A CD2 1 
ATOM 4740 C CE1 . HIS A 1 616  ? 129.492 120.741 146.453 1.00 764.53 ? 616  HIS A CE1 1 
ATOM 4741 N NE2 . HIS A 1 616  ? 128.584 121.049 147.353 1.00 762.89 ? 616  HIS A NE2 1 
ATOM 4742 N N   . TYR A 1 617  ? 124.287 119.996 145.172 1.00 829.84 ? 617  TYR A N   1 
ATOM 4743 C CA  . TYR A 1 617  ? 123.616 119.311 146.269 1.00 852.72 ? 617  TYR A CA  1 
ATOM 4744 C C   . TYR A 1 617  ? 122.826 118.094 145.779 1.00 871.09 ? 617  TYR A C   1 
ATOM 4745 O O   . TYR A 1 617  ? 122.239 117.380 146.591 1.00 883.38 ? 617  TYR A O   1 
ATOM 4746 C CB  . TYR A 1 617  ? 122.716 120.281 147.041 1.00 852.15 ? 617  TYR A CB  1 
ATOM 4747 C CG  . TYR A 1 617  ? 123.460 121.266 147.909 1.00 844.19 ? 617  TYR A CG  1 
ATOM 4748 C CD1 . TYR A 1 617  ? 124.239 120.838 148.973 1.00 840.38 ? 617  TYR A CD1 1 
ATOM 4749 C CD2 . TYR A 1 617  ? 123.390 122.628 147.667 1.00 838.90 ? 617  TYR A CD2 1 
ATOM 4750 C CE1 . TYR A 1 617  ? 124.926 121.737 149.774 1.00 833.08 ? 617  TYR A CE1 1 
ATOM 4751 C CE2 . TYR A 1 617  ? 124.071 123.541 148.456 1.00 831.96 ? 617  TYR A CE2 1 
ATOM 4752 C CZ  . TYR A 1 617  ? 124.842 123.094 149.515 1.00 827.01 ? 617  TYR A CZ  1 
ATOM 4753 O OH  . TYR A 1 617  ? 125.517 123.998 150.299 1.00 818.60 ? 617  TYR A OH  1 
ATOM 4754 N N   . ARG A 1 618  ? 122.807 117.858 144.460 1.00 872.30 ? 618  ARG A N   1 
ATOM 4755 C CA  . ARG A 1 618  ? 122.294 116.610 143.914 1.00 868.39 ? 618  ARG A CA  1 
ATOM 4756 C C   . ARG A 1 618  ? 123.388 115.543 143.936 1.00 839.19 ? 618  ARG A C   1 
ATOM 4757 O O   . ARG A 1 618  ? 123.083 114.353 143.978 1.00 833.32 ? 618  ARG A O   1 
ATOM 4758 C CB  . ARG A 1 618  ? 121.755 116.812 142.494 1.00 885.65 ? 618  ARG A CB  1 
ATOM 4759 C CG  . ARG A 1 618  ? 120.443 117.581 142.433 1.00 903.48 ? 618  ARG A CG  1 
ATOM 4760 C CD  . ARG A 1 618  ? 119.910 117.703 141.018 1.00 911.53 ? 618  ARG A CD  1 
ATOM 4761 N NE  . ARG A 1 618  ? 119.365 116.445 140.525 1.00 915.50 ? 618  ARG A NE  1 
ATOM 4762 C CZ  . ARG A 1 618  ? 118.939 116.241 139.283 1.00 916.93 ? 618  ARG A CZ  1 
ATOM 4763 N NH1 . ARG A 1 618  ? 119.054 117.196 138.376 1.00 917.23 ? 618  ARG A NH1 1 
ATOM 4764 N NH2 . ARG A 1 618  ? 118.411 115.076 138.950 1.00 915.35 ? 618  ARG A NH2 1 
ATOM 4765 N N   . GLU A 1 619  ? 124.656 115.974 143.893 1.00 813.07 ? 619  GLU A N   1 
ATOM 4766 C CA  . GLU A 1 619  ? 125.792 115.064 143.945 1.00 795.90 ? 619  GLU A CA  1 
ATOM 4767 C C   . GLU A 1 619  ? 126.312 114.945 145.378 1.00 813.56 ? 619  GLU A C   1 
ATOM 4768 O O   . GLU A 1 619  ? 126.729 113.865 145.792 1.00 812.54 ? 619  GLU A O   1 
ATOM 4769 C CB  . GLU A 1 619  ? 126.895 115.547 143.001 1.00 770.73 ? 619  GLU A CB  1 
ATOM 4770 C CG  . GLU A 1 619  ? 126.483 115.552 141.538 1.00 751.19 ? 619  GLU A CG  1 
ATOM 4771 C CD  . GLU A 1 619  ? 127.555 116.017 140.566 1.00 738.94 ? 619  GLU A CD  1 
ATOM 4772 O OE1 . GLU A 1 619  ? 127.273 116.046 139.352 1.00 731.01 ? 619  GLU A OE1 1 
ATOM 4773 O OE2 . GLU A 1 619  ? 128.667 116.348 141.023 1.00 735.13 ? 619  GLU A OE2 1 
ATOM 4774 N N   . THR A 1 620  ? 126.283 116.061 146.122 1.00 837.18 ? 620  THR A N   1 
ATOM 4775 C CA  . THR A 1 620  ? 126.855 116.145 147.459 1.00 858.00 ? 620  THR A CA  1 
ATOM 4776 C C   . THR A 1 620  ? 125.735 116.248 148.495 1.00 895.13 ? 620  THR A C   1 
ATOM 4777 O O   . THR A 1 620  ? 124.651 116.741 148.195 1.00 905.02 ? 620  THR A O   1 
ATOM 4778 C CB  . THR A 1 620  ? 127.802 117.349 147.571 1.00 848.76 ? 620  THR A CB  1 
ATOM 4779 O OG1 . THR A 1 620  ? 128.499 117.517 146.336 1.00 843.88 ? 620  THR A OG1 1 
ATOM 4780 C CG2 . THR A 1 620  ? 128.799 117.210 148.701 1.00 845.07 ? 620  THR A CG2 1 
ATOM 4781 N N   . HIS A 1 621  ? 126.010 115.791 149.722 1.00 929.77 ? 621  HIS A N   1 
ATOM 4782 C CA  . HIS A 1 621  ? 125.033 115.850 150.797 1.00 959.05 ? 621  HIS A CA  1 
ATOM 4783 C C   . HIS A 1 621  ? 124.959 117.269 151.357 1.00 999.00 ? 621  HIS A C   1 
ATOM 4784 O O   . HIS A 1 621  ? 125.984 117.863 151.684 1.00 999.00 ? 621  HIS A O   1 
ATOM 4785 C CB  . HIS A 1 621  ? 125.375 114.849 151.907 1.00 933.60 ? 621  HIS A CB  1 
ATOM 4786 C CG  . HIS A 1 621  ? 125.251 113.418 151.502 1.00 904.21 ? 621  HIS A CG  1 
ATOM 4787 N ND1 . HIS A 1 621  ? 126.226 112.731 150.811 1.00 888.38 ? 621  HIS A ND1 1 
ATOM 4788 C CD2 . HIS A 1 621  ? 124.268 112.539 151.726 1.00 888.33 ? 621  HIS A CD2 1 
ATOM 4789 C CE1 . HIS A 1 621  ? 125.826 111.483 150.617 1.00 879.36 ? 621  HIS A CE1 1 
ATOM 4790 N NE2 . HIS A 1 621  ? 124.638 111.345 151.163 1.00 880.04 ? 621  HIS A NE2 1 
ATOM 4791 N N   . LEU A 1 622  ? 123.734 117.804 151.452 1.00 999.00 ? 622  LEU A N   1 
ATOM 4792 C CA  . LEU A 1 622  ? 123.471 119.005 152.229 1.00 999.00 ? 622  LEU A CA  1 
ATOM 4793 C C   . LEU A 1 622  ? 123.583 118.648 153.709 1.00 999.00 ? 622  LEU A C   1 
ATOM 4794 O O   . LEU A 1 622  ? 122.781 117.866 154.218 1.00 999.00 ? 622  LEU A O   1 
ATOM 4795 C CB  . LEU A 1 622  ? 122.074 119.537 151.882 1.00 999.00 ? 622  LEU A CB  1 
ATOM 4796 C CG  . LEU A 1 622  ? 121.617 120.780 152.648 1.00 999.00 ? 622  LEU A CG  1 
ATOM 4797 C CD1 . LEU A 1 622  ? 122.373 122.016 152.187 1.00 999.00 ? 622  LEU A CD1 1 
ATOM 4798 C CD2 . LEU A 1 622  ? 120.118 120.988 152.496 1.00 999.00 ? 622  LEU A CD2 1 
ATOM 4799 N N   . ARG A 1 623  ? 124.596 119.216 154.377 1.00 999.00 ? 623  ARG A N   1 
ATOM 4800 C CA  . ARG A 1 623  ? 124.891 118.910 155.768 1.00 999.00 ? 623  ARG A CA  1 
ATOM 4801 C C   . ARG A 1 623  ? 124.378 120.033 156.666 1.00 999.00 ? 623  ARG A C   1 
ATOM 4802 O O   . ARG A 1 623  ? 124.890 121.150 156.619 1.00 999.00 ? 623  ARG A O   1 
ATOM 4803 C CB  . ARG A 1 623  ? 126.399 118.724 155.967 1.00 999.00 ? 623  ARG A CB  1 
ATOM 4804 C CG  . ARG A 1 623  ? 126.963 117.467 155.321 1.00 999.00 ? 623  ARG A CG  1 
ATOM 4805 C CD  . ARG A 1 623  ? 128.420 117.226 155.669 1.00 999.00 ? 623  ARG A CD  1 
ATOM 4806 N NE  . ARG A 1 623  ? 128.851 115.882 155.306 1.00 999.00 ? 623  ARG A NE  1 
ATOM 4807 C CZ  . ARG A 1 623  ? 130.081 115.409 155.476 1.00 999.00 ? 623  ARG A CZ  1 
ATOM 4808 N NH1 . ARG A 1 623  ? 131.028 116.183 155.975 1.00 999.00 ? 623  ARG A NH1 1 
ATOM 4809 N NH2 . ARG A 1 623  ? 130.358 114.160 155.145 1.00 999.00 ? 623  ARG A NH2 1 
ATOM 4810 N N   . CYS A 1 624  ? 123.357 119.716 157.470 1.00 999.00 ? 624  CYS A N   1 
ATOM 4811 C CA  . CYS A 1 624  ? 122.905 120.579 158.549 1.00 999.00 ? 624  CYS A CA  1 
ATOM 4812 C C   . CYS A 1 624  ? 123.095 119.845 159.874 1.00 999.00 ? 624  CYS A C   1 
ATOM 4813 O O   . CYS A 1 624  ? 123.317 118.635 159.889 1.00 999.00 ? 624  CYS A O   1 
ATOM 4814 C CB  . CYS A 1 624  ? 121.449 120.987 158.358 1.00 999.00 ? 624  CYS A CB  1 
ATOM 4815 S SG  . CYS A 1 624  ? 121.189 122.081 156.937 1.00 999.00 ? 624  CYS A SG  1 
ATOM 4816 N N   . ALA A 1 625  ? 122.981 120.586 160.981 1.00 999.00 ? 625  ALA A N   1 
ATOM 4817 C CA  . ALA A 1 625  ? 123.266 120.059 162.307 1.00 999.00 ? 625  ALA A CA  1 
ATOM 4818 C C   . ALA A 1 625  ? 122.403 118.835 162.619 1.00 999.00 ? 625  ALA A C   1 
ATOM 4819 O O   . ALA A 1 625  ? 122.790 118.014 163.450 1.00 999.00 ? 625  ALA A O   1 
ATOM 4820 C CB  . ALA A 1 625  ? 123.061 121.143 163.338 1.00 999.00 ? 625  ALA A CB  1 
ATOM 4821 N N   . GLU A 1 626  ? 121.243 118.721 161.954 1.00 999.00 ? 626  GLU A N   1 
ATOM 4822 C CA  . GLU A 1 626  ? 120.252 117.708 162.286 1.00 999.00 ? 626  GLU A CA  1 
ATOM 4823 C C   . GLU A 1 626  ? 120.133 116.632 161.204 1.00 999.00 ? 626  GLU A C   1 
ATOM 4824 O O   . GLU A 1 626  ? 119.396 115.667 161.405 1.00 999.00 ? 626  GLU A O   1 
ATOM 4825 C CB  . GLU A 1 626  ? 118.888 118.367 162.506 1.00 999.00 ? 626  GLU A CB  1 
ATOM 4826 C CG  . GLU A 1 626  ? 118.856 119.337 163.676 1.00 999.00 ? 626  GLU A CG  1 
ATOM 4827 C CD  . GLU A 1 626  ? 117.508 119.988 163.938 1.00 999.00 ? 626  GLU A CD  1 
ATOM 4828 O OE1 . GLU A 1 626  ? 117.417 120.788 164.891 1.00 999.00 ? 626  GLU A OE1 1 
ATOM 4829 O OE2 . GLU A 1 626  ? 116.552 119.697 163.191 1.00 999.00 ? 626  GLU A OE2 1 
ATOM 4830 N N   . PHE A 1 627  ? 120.827 116.781 160.062 1.00 999.00 ? 627  PHE A N   1 
ATOM 4831 C CA  . PHE A 1 627  ? 120.705 115.797 158.993 1.00 999.00 ? 627  PHE A CA  1 
ATOM 4832 C C   . PHE A 1 627  ? 121.747 115.975 157.890 1.00 999.00 ? 627  PHE A C   1 
ATOM 4833 O O   . PHE A 1 627  ? 122.249 117.072 157.651 1.00 999.00 ? 627  PHE A O   1 
ATOM 4834 C CB  . PHE A 1 627  ? 119.319 115.855 158.343 1.00 999.00 ? 627  PHE A CB  1 
ATOM 4835 C CG  . PHE A 1 627  ? 118.971 117.155 157.658 1.00 999.00 ? 627  PHE A CG  1 
ATOM 4836 C CD1 . PHE A 1 627  ? 118.519 118.248 158.385 1.00 999.00 ? 627  PHE A CD1 1 
ATOM 4837 C CD2 . PHE A 1 627  ? 119.098 117.288 156.283 1.00 999.00 ? 627  PHE A CD2 1 
ATOM 4838 C CE1 . PHE A 1 627  ? 118.195 119.438 157.753 1.00 999.00 ? 627  PHE A CE1 1 
ATOM 4839 C CE2 . PHE A 1 627  ? 118.781 118.482 155.653 1.00 999.00 ? 627  PHE A CE2 1 
ATOM 4840 C CZ  . PHE A 1 627  ? 118.331 119.554 156.389 1.00 999.00 ? 627  PHE A CZ  1 
ATOM 4841 N N   . GLU A 1 628  ? 122.034 114.860 157.206 1.00 999.00 ? 628  GLU A N   1 
ATOM 4842 C CA  . GLU A 1 628  ? 122.670 114.868 155.898 1.00 999.00 ? 628  GLU A CA  1 
ATOM 4843 C C   . GLU A 1 628  ? 121.665 114.340 154.877 1.00 999.00 ? 628  GLU A C   1 
ATOM 4844 O O   . GLU A 1 628  ? 121.115 113.256 155.063 1.00 999.00 ? 628  GLU A O   1 
ATOM 4845 C CB  . GLU A 1 628  ? 123.935 114.007 155.902 1.00 999.00 ? 628  GLU A CB  1 
ATOM 4846 C CG  . GLU A 1 628  ? 124.982 114.472 156.897 1.00 999.00 ? 628  GLU A CG  1 
ATOM 4847 C CD  . GLU A 1 628  ? 126.383 113.933 156.656 1.00 999.00 ? 628  GLU A CD  1 
ATOM 4848 O OE1 . GLU A 1 628  ? 127.336 114.507 157.219 1.00 999.00 ? 628  GLU A OE1 1 
ATOM 4849 O OE2 . GLU A 1 628  ? 126.522 112.944 155.907 1.00 999.00 ? 628  GLU A OE2 1 
ATOM 4850 N N   . LEU A 1 629  ? 121.425 115.111 153.807 1.00 999.00 ? 629  LEU A N   1 
ATOM 4851 C CA  . LEU A 1 629  ? 120.467 114.721 152.783 1.00 972.42 ? 629  LEU A CA  1 
ATOM 4852 C C   . LEU A 1 629  ? 120.932 115.218 151.415 1.00 940.67 ? 629  LEU A C   1 
ATOM 4853 O O   . LEU A 1 629  ? 121.390 116.351 151.279 1.00 948.61 ? 629  LEU A O   1 
ATOM 4854 C CB  . LEU A 1 629  ? 119.084 115.269 153.162 1.00 958.72 ? 629  LEU A CB  1 
ATOM 4855 C CG  . LEU A 1 629  ? 117.960 115.038 152.148 1.00 943.46 ? 629  LEU A CG  1 
ATOM 4856 C CD1 . LEU A 1 629  ? 116.630 114.821 152.856 1.00 939.08 ? 629  LEU A CD1 1 
ATOM 4857 C CD2 . LEU A 1 629  ? 117.839 116.203 151.172 1.00 932.27 ? 629  LEU A CD2 1 
ATOM 4858 N N   . ARG A 1 630  ? 120.826 114.333 150.415 1.00 895.18 ? 630  ARG A N   1 
ATOM 4859 C CA  . ARG A 1 630  ? 121.132 114.648 149.029 1.00 855.15 ? 630  ARG A CA  1 
ATOM 4860 C C   . ARG A 1 630  ? 119.818 114.901 148.291 1.00 824.74 ? 630  ARG A C   1 
ATOM 4861 O O   . ARG A 1 630  ? 118.837 114.198 148.525 1.00 819.77 ? 630  ARG A O   1 
ATOM 4862 C CB  . ARG A 1 630  ? 121.921 113.485 148.415 1.00 840.32 ? 630  ARG A CB  1 
ATOM 4863 C CG  . ARG A 1 630  ? 122.238 113.627 146.932 1.00 825.86 ? 630  ARG A CG  1 
ATOM 4864 C CD  . ARG A 1 630  ? 122.904 112.376 146.388 1.00 809.12 ? 630  ARG A CD  1 
ATOM 4865 N NE  . ARG A 1 630  ? 124.295 112.250 146.801 1.00 796.19 ? 630  ARG A NE  1 
ATOM 4866 C CZ  . ARG A 1 630  ? 125.081 111.221 146.499 1.00 784.84 ? 630  ARG A CZ  1 
ATOM 4867 N NH1 . ARG A 1 630  ? 124.603 110.201 145.810 1.00 780.98 ? 630  ARG A NH1 1 
ATOM 4868 N NH2 . ARG A 1 630  ? 126.344 111.217 146.889 1.00 783.75 ? 630  ARG A NH2 1 
ATOM 4869 N N   . LEU A 1 631  ? 119.804 115.912 147.413 1.00 786.85 ? 631  LEU A N   1 
ATOM 4870 C CA  . LEU A 1 631  ? 118.629 116.215 146.609 1.00 751.20 ? 631  LEU A CA  1 
ATOM 4871 C C   . LEU A 1 631  ? 118.448 115.117 145.562 1.00 705.51 ? 631  LEU A C   1 
ATOM 4872 O O   . LEU A 1 631  ? 119.387 114.796 144.836 1.00 714.71 ? 631  LEU A O   1 
ATOM 4873 C CB  . LEU A 1 631  ? 118.803 117.590 145.951 1.00 757.71 ? 631  LEU A CB  1 
ATOM 4874 C CG  . LEU A 1 631  ? 118.888 118.781 146.907 1.00 758.41 ? 631  LEU A CG  1 
ATOM 4875 C CD1 . LEU A 1 631  ? 118.997 120.089 146.135 1.00 762.76 ? 631  LEU A CD1 1 
ATOM 4876 C CD2 . LEU A 1 631  ? 117.691 118.820 147.846 1.00 751.58 ? 631  LEU A CD2 1 
ATOM 4877 N N   . THR A 1 632  ? 117.235 114.547 145.500 1.00 645.88 ? 632  THR A N   1 
ATOM 4878 C CA  . THR A 1 632  ? 116.949 113.403 144.645 1.00 599.22 ? 632  THR A CA  1 
ATOM 4879 C C   . THR A 1 632  ? 116.050 113.839 143.486 1.00 548.43 ? 632  THR A C   1 
ATOM 4880 O O   . THR A 1 632  ? 116.537 114.426 142.520 1.00 549.44 ? 632  THR A O   1 
ATOM 4881 C CB  . THR A 1 632  ? 116.399 112.224 145.466 1.00 600.52 ? 632  THR A CB  1 
ATOM 4882 O OG1 . THR A 1 632  ? 115.260 112.626 146.229 1.00 600.93 ? 632  THR A OG1 1 
ATOM 4883 C CG2 . THR A 1 632  ? 117.428 111.644 146.411 1.00 601.22 ? 632  THR A CG2 1 
ATOM 4884 N N   . ASP A 1 633  ? 114.743 113.561 143.587 1.00 491.25 ? 633  ASP A N   1 
ATOM 4885 C CA  . ASP A 1 633  ? 113.829 113.725 142.466 1.00 445.78 ? 633  ASP A CA  1 
ATOM 4886 C C   . ASP A 1 633  ? 113.290 115.155 142.440 1.00 400.35 ? 633  ASP A C   1 
ATOM 4887 O O   . ASP A 1 633  ? 112.726 115.623 143.425 1.00 396.29 ? 633  ASP A O   1 
ATOM 4888 C CB  . ASP A 1 633  ? 112.677 112.716 142.533 1.00 445.95 ? 633  ASP A CB  1 
ATOM 4889 C CG  . ASP A 1 633  ? 113.125 111.264 142.479 1.00 448.88 ? 633  ASP A CG  1 
ATOM 4890 O OD1 . ASP A 1 633  ? 113.938 110.937 141.591 1.00 449.81 ? 633  ASP A OD1 1 
ATOM 4891 O OD2 . ASP A 1 633  ? 112.645 110.468 143.313 1.00 449.57 ? 633  ASP A OD2 1 
ATOM 4892 N N   . PRO A 1 634  ? 113.430 115.893 141.313 1.00 355.72 ? 634  PRO A N   1 
ATOM 4893 C CA  . PRO A 1 634  ? 112.800 117.208 141.177 1.00 336.43 ? 634  PRO A CA  1 
ATOM 4894 C C   . PRO A 1 634  ? 111.306 117.083 140.879 1.00 314.68 ? 634  PRO A C   1 
ATOM 4895 O O   . PRO A 1 634  ? 110.908 116.296 140.023 1.00 307.45 ? 634  PRO A O   1 
ATOM 4896 C CB  . PRO A 1 634  ? 113.569 117.825 139.998 1.00 339.06 ? 634  PRO A CB  1 
ATOM 4897 C CG  . PRO A 1 634  ? 113.932 116.635 139.136 1.00 339.48 ? 634  PRO A CG  1 
ATOM 4898 C CD  . PRO A 1 634  ? 114.199 115.511 140.117 1.00 344.27 ? 634  PRO A CD  1 
ATOM 4899 N N   . VAL A 1 635  ? 110.477 117.858 141.588 1.00 295.41 ? 635  VAL A N   1 
ATOM 4900 C CA  . VAL A 1 635  ? 109.035 117.812 141.381 1.00 282.52 ? 635  VAL A CA  1 
ATOM 4901 C C   . VAL A 1 635  ? 108.605 119.045 140.583 1.00 276.19 ? 635  VAL A C   1 
ATOM 4902 O O   . VAL A 1 635  ? 108.426 120.119 141.149 1.00 291.06 ? 635  VAL A O   1 
ATOM 4903 C CB  . VAL A 1 635  ? 108.268 117.678 142.714 1.00 291.48 ? 635  VAL A CB  1 
ATOM 4904 C CG1 . VAL A 1 635  ? 108.840 118.555 143.820 1.00 295.33 ? 635  VAL A CG1 1 
ATOM 4905 C CG2 . VAL A 1 635  ? 106.776 117.934 142.548 1.00 296.25 ? 635  VAL A CG2 1 
ATOM 4906 N N   . PRO A 1 636  ? 108.390 118.940 139.247 1.00 265.23 ? 636  PRO A N   1 
ATOM 4907 C CA  . PRO A 1 636  ? 108.249 120.125 138.391 1.00 258.59 ? 636  PRO A CA  1 
ATOM 4908 C C   . PRO A 1 636  ? 106.889 120.651 137.933 1.00 239.04 ? 636  PRO A C   1 
ATOM 4909 O O   . PRO A 1 636  ? 106.654 120.770 136.733 1.00 241.19 ? 636  PRO A O   1 
ATOM 4910 C CB  . PRO A 1 636  ? 108.897 119.556 137.125 1.00 269.43 ? 636  PRO A CB  1 
ATOM 4911 C CG  . PRO A 1 636  ? 108.332 118.162 137.036 1.00 268.54 ? 636  PRO A CG  1 
ATOM 4912 C CD  . PRO A 1 636  ? 108.314 117.685 138.475 1.00 264.12 ? 636  PRO A CD  1 
ATOM 4913 N N   . ASN A 1 637  ? 105.991 120.999 138.855 1.00 231.48 ? 637  ASN A N   1 
ATOM 4914 C CA  . ASN A 1 637  ? 104.699 121.515 138.430 1.00 236.30 ? 637  ASN A CA  1 
ATOM 4915 C C   . ASN A 1 637  ? 104.350 122.798 139.177 1.00 219.68 ? 637  ASN A C   1 
ATOM 4916 O O   . ASN A 1 637  ? 103.424 122.796 139.982 1.00 224.54 ? 637  ASN A O   1 
ATOM 4917 C CB  . ASN A 1 637  ? 103.587 120.476 138.613 1.00 261.27 ? 637  ASN A CB  1 
ATOM 4918 C CG  . ASN A 1 637  ? 103.734 119.263 137.718 1.00 279.12 ? 637  ASN A CG  1 
ATOM 4919 O OD1 . ASN A 1 637  ? 102.910 119.032 136.836 1.00 286.02 ? 637  ASN A OD1 1 
ATOM 4920 N ND2 . ASN A 1 637  ? 104.770 118.472 137.942 1.00 282.31 ? 637  ASN A ND2 1 
ATOM 4921 N N   . PRO A 1 638  ? 105.037 123.938 138.925 1.00 211.84 ? 638  PRO A N   1 
ATOM 4922 C CA  . PRO A 1 638  ? 104.600 125.218 139.479 1.00 217.93 ? 638  PRO A CA  1 
ATOM 4923 C C   . PRO A 1 638  ? 103.324 125.653 138.764 1.00 217.09 ? 638  PRO A C   1 
ATOM 4924 O O   . PRO A 1 638  ? 102.243 125.151 139.061 1.00 217.20 ? 638  PRO A O   1 
ATOM 4925 C CB  . PRO A 1 638  ? 105.782 126.160 139.216 1.00 222.85 ? 638  PRO A CB  1 
ATOM 4926 C CG  . PRO A 1 638  ? 106.474 125.563 138.003 1.00 218.42 ? 638  PRO A CG  1 
ATOM 4927 C CD  . PRO A 1 638  ? 106.257 124.068 138.114 1.00 207.99 ? 638  PRO A CD  1 
ATOM 4928 N N   . ASN A 1 639  ? 103.476 126.563 137.799 1.00 217.61 ? 639  ASN A N   1 
ATOM 4929 C CA  . ASN A 1 639  ? 102.395 126.961 136.917 1.00 215.84 ? 639  ASN A CA  1 
ATOM 4930 C C   . ASN A 1 639  ? 102.957 127.035 135.501 1.00 189.24 ? 639  ASN A C   1 
ATOM 4931 O O   . ASN A 1 639  ? 103.090 128.114 134.925 1.00 201.88 ? 639  ASN A O   1 
ATOM 4932 C CB  . ASN A 1 639  ? 101.753 128.282 137.353 1.00 241.83 ? 639  ASN A CB  1 
ATOM 4933 C CG  . ASN A 1 639  ? 101.128 128.209 138.730 1.00 259.38 ? 639  ASN A CG  1 
ATOM 4934 O OD1 . ASN A 1 639  ? 101.507 128.959 139.628 1.00 269.76 ? 639  ASN A OD1 1 
ATOM 4935 N ND2 . ASN A 1 639  ? 100.173 127.311 138.907 1.00 260.78 ? 639  ASN A ND2 1 
ATOM 4936 N N   . PRO A 1 640  ? 103.336 125.884 134.902 1.00 151.03 ? 640  PRO A N   1 
ATOM 4937 C CA  . PRO A 1 640  ? 103.950 125.886 133.580 1.00 131.09 ? 640  PRO A CA  1 
ATOM 4938 C C   . PRO A 1 640  ? 102.951 126.501 132.608 1.00 119.36 ? 640  PRO A C   1 
ATOM 4939 O O   . PRO A 1 640  ? 103.324 127.302 131.761 1.00 123.05 ? 640  PRO A O   1 
ATOM 4940 C CB  . PRO A 1 640  ? 104.236 124.409 133.286 1.00 133.40 ? 640  PRO A CB  1 
ATOM 4941 C CG  . PRO A 1 640  ? 104.147 123.724 134.627 1.00 143.44 ? 640  PRO A CG  1 
ATOM 4942 C CD  . PRO A 1 640  ? 103.136 124.524 135.419 1.00 147.67 ? 640  PRO A CD  1 
ATOM 4943 N N   . HIS A 1 641  ? 101.674 126.164 132.793 1.00 105.21 ? 641  HIS A N   1 
ATOM 4944 C CA  . HIS A 1 641  ? 100.604 126.731 131.991 1.00 105.64 ? 641  HIS A CA  1 
ATOM 4945 C C   . HIS A 1 641  ? 100.139 128.067 132.564 1.00 111.73 ? 641  HIS A C   1 
ATOM 4946 O O   . HIS A 1 641  ? 99.020  128.153 133.056 1.00 106.91 ? 641  HIS A O   1 
ATOM 4947 C CB  . HIS A 1 641  ? 99.427  125.756 131.948 1.00 117.26 ? 641  HIS A CB  1 
ATOM 4948 C CG  . HIS A 1 641  ? 99.056  125.234 133.298 1.00 142.02 ? 641  HIS A CG  1 
ATOM 4949 N ND1 . HIS A 1 641  ? 99.205  123.908 133.649 1.00 172.92 ? 641  HIS A ND1 1 
ATOM 4950 C CD2 . HIS A 1 641  ? 98.584  125.845 134.390 1.00 158.18 ? 641  HIS A CD2 1 
ATOM 4951 C CE1 . HIS A 1 641  ? 98.822  123.734 134.904 1.00 182.03 ? 641  HIS A CE1 1 
ATOM 4952 N NE2 . HIS A 1 641  ? 98.434  124.898 135.372 1.00 177.20 ? 641  HIS A NE2 1 
ATOM 4953 N N   . GLU A 1 642  ? 100.978 129.108 132.477 1.00 123.11 ? 642  GLU A N   1 
ATOM 4954 C CA  . GLU A 1 642  ? 100.586 130.455 132.878 1.00 131.38 ? 642  GLU A CA  1 
ATOM 4955 C C   . GLU A 1 642  ? 101.623 131.462 132.395 1.00 130.31 ? 642  GLU A C   1 
ATOM 4956 O O   . GLU A 1 642  ? 101.258 132.540 131.933 1.00 141.59 ? 642  GLU A O   1 
ATOM 4957 C CB  . GLU A 1 642  ? 100.400 130.574 134.396 1.00 145.05 ? 642  GLU A CB  1 
ATOM 4958 C CG  . GLU A 1 642  ? 100.065 131.980 134.886 1.00 154.25 ? 642  GLU A CG  1 
ATOM 4959 C CD  . GLU A 1 642  ? 98.747  132.580 134.414 1.00 169.06 ? 642  GLU A CD  1 
ATOM 4960 O OE1 . GLU A 1 642  ? 98.449  133.725 134.817 1.00 178.82 ? 642  GLU A OE1 1 
ATOM 4961 O OE2 . GLU A 1 642  ? 98.017  131.915 133.653 1.00 176.21 ? 642  GLU A OE2 1 
ATOM 4962 N N   . SER A 1 643  ? 102.906 131.113 132.542 1.00 133.18 ? 643  SER A N   1 
ATOM 4963 C CA  . SER A 1 643  ? 103.992 131.929 132.025 1.00 144.19 ? 643  SER A CA  1 
ATOM 4964 C C   . SER A 1 643  ? 103.893 132.070 130.505 1.00 156.97 ? 643  SER A C   1 
ATOM 4965 O O   . SER A 1 643  ? 104.139 133.149 129.970 1.00 159.42 ? 643  SER A O   1 
ATOM 4966 C CB  . SER A 1 643  ? 105.329 131.362 132.432 1.00 144.14 ? 643  SER A CB  1 
ATOM 4967 O OG  . SER A 1 643  ? 106.397 132.153 131.928 1.00 143.25 ? 643  SER A OG  1 
ATOM 4968 N N   . LYS A 1 644  ? 103.525 130.982 129.815 1.00 161.94 ? 644  LYS A N   1 
ATOM 4969 C CA  . LYS A 1 644  ? 103.602 130.934 128.361 1.00 156.80 ? 644  LYS A CA  1 
ATOM 4970 C C   . LYS A 1 644  ? 102.493 131.788 127.743 1.00 135.22 ? 644  LYS A C   1 
ATOM 4971 O O   . LYS A 1 644  ? 101.439 131.985 128.342 1.00 128.77 ? 644  LYS A O   1 
ATOM 4972 C CB  . LYS A 1 644  ? 103.586 129.479 127.880 1.00 163.60 ? 644  LYS A CB  1 
ATOM 4973 C CG  . LYS A 1 644  ? 104.768 128.657 128.382 1.00 166.59 ? 644  LYS A CG  1 
ATOM 4974 C CD  . LYS A 1 644  ? 104.767 127.205 127.960 1.00 172.54 ? 644  LYS A CD  1 
ATOM 4975 C CE  . LYS A 1 644  ? 104.982 126.984 126.478 1.00 179.38 ? 644  LYS A CE  1 
ATOM 4976 N NZ  . LYS A 1 644  ? 106.179 127.692 125.964 1.00 184.55 ? 644  LYS A NZ  1 
ATOM 4977 N N   . PRO A 1 645  ? 102.725 132.347 126.531 1.00 125.34 ? 645  PRO A N   1 
ATOM 4978 C CA  . PRO A 1 645  ? 101.817 133.322 125.930 1.00 115.16 ? 645  PRO A CA  1 
ATOM 4979 C C   . PRO A 1 645  ? 100.421 132.786 125.647 1.00 102.55 ? 645  PRO A C   1 
ATOM 4980 O O   . PRO A 1 645  ? 99.441  133.496 125.840 1.00 106.55 ? 645  PRO A O   1 
ATOM 4981 C CB  . PRO A 1 645  ? 102.468 133.680 124.585 1.00 129.93 ? 645  PRO A CB  1 
ATOM 4982 C CG  . PRO A 1 645  ? 103.918 133.276 124.743 1.00 142.82 ? 645  PRO A CG  1 
ATOM 4983 C CD  . PRO A 1 645  ? 103.892 132.083 125.675 1.00 140.68 ? 645  PRO A CD  1 
ATOM 4984 N N   . TRP A 1 646  ? 100.352 131.535 125.191 1.00 100.15 ? 646  TRP A N   1 
ATOM 4985 C CA  . TRP A 1 646  ? 99.109  130.950 124.709 1.00 112.93 ? 646  TRP A CA  1 
ATOM 4986 C C   . TRP A 1 646  ? 98.179  130.584 125.865 1.00 125.21 ? 646  TRP A C   1 
ATOM 4987 O O   . TRP A 1 646  ? 97.624  129.493 125.868 1.00 113.58 ? 646  TRP A O   1 
ATOM 4988 C CB  . TRP A 1 646  ? 99.395  129.712 123.843 1.00 108.28 ? 646  TRP A CB  1 
ATOM 4989 C CG  . TRP A 1 646  ? 100.395 128.780 124.453 1.00 98.09  ? 646  TRP A CG  1 
ATOM 4990 C CD1 . TRP A 1 646  ? 101.751 128.882 124.360 1.00 99.71  ? 646  TRP A CD1 1 
ATOM 4991 C CD2 . TRP A 1 646  ? 100.136 127.655 125.309 1.00 89.44  ? 646  TRP A CD2 1 
ATOM 4992 N NE1 . TRP A 1 646  ? 102.355 127.887 125.074 1.00 96.52  ? 646  TRP A NE1 1 
ATOM 4993 C CE2 . TRP A 1 646  ? 101.392 127.117 125.667 1.00 95.56  ? 646  TRP A CE2 1 
ATOM 4994 C CE3 . TRP A 1 646  ? 98.977  127.045 125.800 1.00 90.73  ? 646  TRP A CE3 1 
ATOM 4995 C CZ2 . TRP A 1 646  ? 101.518 126.007 126.502 1.00 110.13 ? 646  TRP A CZ2 1 
ATOM 4996 C CZ3 . TRP A 1 646  ? 99.103  125.945 126.622 1.00 109.40 ? 646  TRP A CZ3 1 
ATOM 4997 C CH2 . TRP A 1 646  ? 100.357 125.428 126.962 1.00 120.02 ? 646  TRP A CH2 1 
ATOM 4998 N N   . TYR A 1 647  ? 97.981  131.485 126.835 1.00 130.97 ? 647  TYR A N   1 
ATOM 4999 C CA  . TYR A 1 647  ? 97.054  131.197 127.918 1.00 129.05 ? 647  TYR A CA  1 
ATOM 5000 C C   . TYR A 1 647  ? 96.169  132.404 128.202 1.00 116.87 ? 647  TYR A C   1 
ATOM 5001 O O   . TYR A 1 647  ? 96.661  133.472 128.556 1.00 115.58 ? 647  TYR A O   1 
ATOM 5002 C CB  . TYR A 1 647  ? 97.780  130.779 129.200 1.00 136.70 ? 647  TYR A CB  1 
ATOM 5003 C CG  . TYR A 1 647  ? 96.870  130.280 130.298 1.00 138.48 ? 647  TYR A CG  1 
ATOM 5004 C CD1 . TYR A 1 647  ? 95.503  130.145 130.107 1.00 133.15 ? 647  TYR A CD1 1 
ATOM 5005 C CD2 . TYR A 1 647  ? 97.374  129.929 131.538 1.00 132.43 ? 647  TYR A CD2 1 
ATOM 5006 C CE1 . TYR A 1 647  ? 94.669  129.671 131.103 1.00 129.10 ? 647  TYR A CE1 1 
ATOM 5007 C CE2 . TYR A 1 647  ? 96.555  129.459 132.553 1.00 126.72 ? 647  TYR A CE2 1 
ATOM 5008 C CZ  . TYR A 1 647  ? 95.195  129.339 132.336 1.00 127.08 ? 647  TYR A CZ  1 
ATOM 5009 O OH  . TYR A 1 647  ? 94.369  128.879 133.323 1.00 120.43 ? 647  TYR A OH  1 
ATOM 5010 N N   . TYR A 1 648  ? 94.855  132.199 128.066 1.00 111.46 ? 648  TYR A N   1 
ATOM 5011 C CA  . TYR A 1 648  ? 93.875  133.201 128.435 1.00 111.38 ? 648  TYR A CA  1 
ATOM 5012 C C   . TYR A 1 648  ? 93.227  132.780 129.750 1.00 115.71 ? 648  TYR A C   1 
ATOM 5013 O O   . TYR A 1 648  ? 92.807  131.638 129.898 1.00 116.46 ? 648  TYR A O   1 
ATOM 5014 C CB  . TYR A 1 648  ? 92.886  133.403 127.285 1.00 105.96 ? 648  TYR A CB  1 
ATOM 5015 C CG  . TYR A 1 648  ? 93.493  134.021 126.049 1.00 105.66 ? 648  TYR A CG  1 
ATOM 5016 C CD1 . TYR A 1 648  ? 94.231  135.188 126.138 1.00 113.17 ? 648  TYR A CD1 1 
ATOM 5017 C CD2 . TYR A 1 648  ? 93.324  133.462 124.793 1.00 105.04 ? 648  TYR A CD2 1 
ATOM 5018 C CE1 . TYR A 1 648  ? 94.797  135.778 125.022 1.00 117.18 ? 648  TYR A CE1 1 
ATOM 5019 C CE2 . TYR A 1 648  ? 93.889  134.037 123.665 1.00 113.59 ? 648  TYR A CE2 1 
ATOM 5020 C CZ  . TYR A 1 648  ? 94.626  135.204 123.776 1.00 116.43 ? 648  TYR A CZ  1 
ATOM 5021 O OH  . TYR A 1 648  ? 95.198  135.816 122.681 1.00 113.70 ? 648  TYR A OH  1 
ATOM 5022 N N   . ASP A 1 649  ? 93.209  133.709 130.713 1.00 121.95 ? 649  ASP A N   1 
ATOM 5023 C CA  . ASP A 1 649  ? 92.600  133.489 132.013 1.00 120.01 ? 649  ASP A CA  1 
ATOM 5024 C C   . ASP A 1 649  ? 91.255  134.205 132.030 1.00 127.43 ? 649  ASP A C   1 
ATOM 5025 O O   . ASP A 1 649  ? 91.208  135.425 131.887 1.00 132.80 ? 649  ASP A O   1 
ATOM 5026 C CB  . ASP A 1 649  ? 93.494  134.006 133.144 1.00 118.14 ? 649  ASP A CB  1 
ATOM 5027 C CG  . ASP A 1 649  ? 94.882  133.386 133.170 1.00 121.86 ? 649  ASP A CG  1 
ATOM 5028 O OD1 . ASP A 1 649  ? 95.606  133.519 132.162 1.00 117.33 ? 649  ASP A OD1 1 
ATOM 5029 O OD2 . ASP A 1 649  ? 95.227  132.769 134.199 1.00 131.51 ? 649  ASP A OD2 1 
ATOM 5030 N N   . SER A 1 650  ? 90.175  133.427 132.164 1.00 139.81 ? 650  SER A N   1 
ATOM 5031 C CA  . SER A 1 650  ? 88.823  133.944 132.320 1.00 157.19 ? 650  SER A CA  1 
ATOM 5032 C C   . SER A 1 650  ? 88.203  134.323 130.977 1.00 143.64 ? 650  SER A C   1 
ATOM 5033 O O   . SER A 1 650  ? 87.074  134.810 130.945 1.00 146.98 ? 650  SER A O   1 
ATOM 5034 C CB  . SER A 1 650  ? 88.776  135.121 133.273 1.00 177.94 ? 650  SER A CB  1 
ATOM 5035 O OG  . SER A 1 650  ? 89.050  136.344 132.599 1.00 181.60 ? 650  SER A OG  1 
ATOM 5036 N N   . LEU A 1 651  ? 88.931  134.114 129.874 1.00 121.66 ? 651  LEU A N   1 
ATOM 5037 C CA  . LEU A 1 651  ? 88.354  134.382 128.570 1.00 112.50 ? 651  LEU A CA  1 
ATOM 5038 C C   . LEU A 1 651  ? 87.021  133.645 128.514 1.00 105.34 ? 651  LEU A C   1 
ATOM 5039 O O   . LEU A 1 651  ? 86.958  132.472 128.870 1.00 107.94 ? 651  LEU A O   1 
ATOM 5040 C CB  . LEU A 1 651  ? 89.310  133.915 127.469 1.00 118.15 ? 651  LEU A CB  1 
ATOM 5041 C CG  . LEU A 1 651  ? 89.511  134.912 126.329 1.00 138.21 ? 651  LEU A CG  1 
ATOM 5042 C CD1 . LEU A 1 651  ? 90.463  136.026 126.750 1.00 150.91 ? 651  LEU A CD1 1 
ATOM 5043 C CD2 . LEU A 1 651  ? 90.011  134.223 125.069 1.00 143.97 ? 651  LEU A CD2 1 
ATOM 5044 N N   . SER A 1 652  ? 85.956  134.365 128.153 1.00 108.02 ? 652  SER A N   1 
ATOM 5045 C CA  . SER A 1 652  ? 84.629  133.783 128.051 1.00 120.78 ? 652  SER A CA  1 
ATOM 5046 C C   . SER A 1 652  ? 84.589  132.789 126.895 1.00 121.62 ? 652  SER A C   1 
ATOM 5047 O O   . SER A 1 652  ? 85.217  133.022 125.867 1.00 124.17 ? 652  SER A O   1 
ATOM 5048 C CB  . SER A 1 652  ? 83.584  134.852 127.865 1.00 131.96 ? 652  SER A CB  1 
ATOM 5049 O OG  . SER A 1 652  ? 82.345  134.281 127.466 1.00 138.44 ? 652  SER A OG  1 
ATOM 5050 N N   . ARG A 1 653  ? 83.826  131.701 127.055 1.00 121.47 ? 653  ARG A N   1 
ATOM 5051 C CA  . ARG A 1 653  ? 83.700  130.730 125.982 1.00 119.71 ? 653  ARG A CA  1 
ATOM 5052 C C   . ARG A 1 653  ? 83.286  131.457 124.708 1.00 117.41 ? 653  ARG A C   1 
ATOM 5053 O O   . ARG A 1 653  ? 83.880  131.241 123.658 1.00 121.30 ? 653  ARG A O   1 
ATOM 5054 C CB  . ARG A 1 653  ? 82.691  129.619 126.284 1.00 122.72 ? 653  ARG A CB  1 
ATOM 5055 C CG  . ARG A 1 653  ? 82.478  128.701 125.087 1.00 126.18 ? 653  ARG A CG  1 
ATOM 5056 C CD  . ARG A 1 653  ? 81.652  127.452 125.317 1.00 127.39 ? 653  ARG A CD  1 
ATOM 5057 N NE  . ARG A 1 653  ? 81.461  126.766 124.045 1.00 127.03 ? 653  ARG A NE  1 
ATOM 5058 C CZ  . ARG A 1 653  ? 80.959  125.544 123.906 1.00 135.63 ? 653  ARG A CZ  1 
ATOM 5059 N NH1 . ARG A 1 653  ? 80.537  124.871 124.961 1.00 144.75 ? 653  ARG A NH1 1 
ATOM 5060 N NH2 . ARG A 1 653  ? 80.884  125.000 122.703 1.00 134.80 ? 653  ARG A NH2 1 
ATOM 5061 N N   . GLY A 1 654  ? 82.266  132.313 124.819 1.00 120.71 ? 654  GLY A N   1 
ATOM 5062 C CA  . GLY A 1 654  ? 81.801  133.104 123.693 1.00 130.96 ? 654  GLY A CA  1 
ATOM 5063 C C   . GLY A 1 654  ? 82.918  133.945 123.074 1.00 143.18 ? 654  GLY A C   1 
ATOM 5064 O O   . GLY A 1 654  ? 83.130  133.895 121.863 1.00 147.69 ? 654  GLY A O   1 
ATOM 5065 N N   . GLU A 1 655  ? 83.631  134.699 123.923 1.00 151.20 ? 655  GLU A N   1 
ATOM 5066 C CA  . GLU A 1 655  ? 84.588  135.699 123.467 1.00 157.04 ? 655  GLU A CA  1 
ATOM 5067 C C   . GLU A 1 655  ? 85.733  135.039 122.702 1.00 145.31 ? 655  GLU A C   1 
ATOM 5068 O O   . GLU A 1 655  ? 86.118  135.516 121.638 1.00 151.68 ? 655  GLU A O   1 
ATOM 5069 C CB  . GLU A 1 655  ? 85.130  136.513 124.645 1.00 172.20 ? 655  GLU A CB  1 
ATOM 5070 C CG  . GLU A 1 655  ? 84.117  137.481 125.231 1.00 188.34 ? 655  GLU A CG  1 
ATOM 5071 C CD  . GLU A 1 655  ? 84.630  138.317 126.392 1.00 200.36 ? 655  GLU A CD  1 
ATOM 5072 O OE1 . GLU A 1 655  ? 84.653  139.559 126.260 1.00 207.62 ? 655  GLU A OE1 1 
ATOM 5073 O OE2 . GLU A 1 655  ? 85.003  137.729 127.427 1.00 205.98 ? 655  GLU A OE2 1 
ATOM 5074 N N   . ALA A 1 656  ? 86.272  133.948 123.257 1.00 138.35 ? 656  ALA A N   1 
ATOM 5075 C CA  . ALA A 1 656  ? 87.376  133.239 122.633 1.00 136.56 ? 656  ALA A CA  1 
ATOM 5076 C C   . ALA A 1 656  ? 86.991  132.837 121.216 1.00 129.47 ? 656  ALA A C   1 
ATOM 5077 O O   . ALA A 1 656  ? 87.730  133.106 120.275 1.00 128.69 ? 656  ALA A O   1 
ATOM 5078 C CB  . ALA A 1 656  ? 87.758  132.026 123.448 1.00 140.46 ? 656  ALA A CB  1 
ATOM 5079 N N   . GLU A 1 657  ? 85.824  132.199 121.084 1.00 128.91 ? 657  GLU A N   1 
ATOM 5080 C CA  . GLU A 1 657  ? 85.355  131.748 119.787 1.00 132.76 ? 657  GLU A CA  1 
ATOM 5081 C C   . GLU A 1 657  ? 85.503  132.919 118.822 1.00 134.64 ? 657  GLU A C   1 
ATOM 5082 O O   . GLU A 1 657  ? 86.094  132.781 117.753 1.00 137.44 ? 657  GLU A O   1 
ATOM 5083 C CB  . GLU A 1 657  ? 83.914  131.235 119.871 1.00 142.41 ? 657  GLU A CB  1 
ATOM 5084 C CG  . GLU A 1 657  ? 83.649  130.050 118.960 1.00 157.47 ? 657  GLU A CG  1 
ATOM 5085 C CD  . GLU A 1 657  ? 82.226  129.517 118.943 1.00 173.95 ? 657  GLU A CD  1 
ATOM 5086 O OE1 . GLU A 1 657  ? 81.996  128.481 118.282 1.00 178.65 ? 657  GLU A OE1 1 
ATOM 5087 O OE2 . GLU A 1 657  ? 81.348  130.140 119.577 1.00 184.35 ? 657  GLU A OE2 1 
ATOM 5088 N N   . ASP A 1 658  ? 85.022  134.087 119.260 1.00 144.71 ? 658  ASP A N   1 
ATOM 5089 C CA  . ASP A 1 658  ? 85.135  135.306 118.480 1.00 156.41 ? 658  ASP A CA  1 
ATOM 5090 C C   . ASP A 1 658  ? 86.615  135.651 118.307 1.00 141.46 ? 658  ASP A C   1 
ATOM 5091 O O   . ASP A 1 658  ? 87.056  135.949 117.198 1.00 141.17 ? 658  ASP A O   1 
ATOM 5092 C CB  . ASP A 1 658  ? 84.328  136.440 119.123 1.00 177.74 ? 658  ASP A CB  1 
ATOM 5093 C CG  . ASP A 1 658  ? 83.846  137.497 118.143 1.00 201.62 ? 658  ASP A CG  1 
ATOM 5094 O OD1 . ASP A 1 658  ? 83.142  137.125 117.179 1.00 210.41 ? 658  ASP A OD1 1 
ATOM 5095 O OD2 . ASP A 1 658  ? 84.161  138.686 118.359 1.00 216.97 ? 658  ASP A OD2 1 
ATOM 5096 N N   . MET A 1 659  ? 87.382  135.595 119.404 1.00 125.99 ? 659  MET A N   1 
ATOM 5097 C CA  . MET A 1 659  ? 88.801  135.909 119.344 1.00 115.31 ? 659  MET A CA  1 
ATOM 5098 C C   . MET A 1 659  ? 89.463  135.062 118.264 1.00 112.13 ? 659  MET A C   1 
ATOM 5099 O O   . MET A 1 659  ? 90.284  135.553 117.494 1.00 111.43 ? 659  MET A O   1 
ATOM 5100 C CB  . MET A 1 659  ? 89.508  135.639 120.677 1.00 117.07 ? 659  MET A CB  1 
ATOM 5101 C CG  . MET A 1 659  ? 90.231  136.835 121.236 1.00 129.92 ? 659  MET A CG  1 
ATOM 5102 S SD  . MET A 1 659  ? 91.960  136.414 121.499 1.00 146.08 ? 659  MET A SD  1 
ATOM 5103 C CE  . MET A 1 659  ? 92.501  136.328 119.793 1.00 143.66 ? 659  MET A CE  1 
ATOM 5104 N N   . LEU A 1 660  ? 89.079  133.785 118.210 1.00 116.28 ? 660  LEU A N   1 
ATOM 5105 C CA  . LEU A 1 660  ? 89.714  132.836 117.317 1.00 116.94 ? 660  LEU A CA  1 
ATOM 5106 C C   . LEU A 1 660  ? 89.316  133.135 115.877 1.00 120.44 ? 660  LEU A C   1 
ATOM 5107 O O   . LEU A 1 660  ? 90.162  133.103 114.991 1.00 136.44 ? 660  LEU A O   1 
ATOM 5108 C CB  . LEU A 1 660  ? 89.320  131.417 117.738 1.00 116.38 ? 660  LEU A CB  1 
ATOM 5109 C CG  . LEU A 1 660  ? 90.384  130.345 117.515 1.00 121.52 ? 660  LEU A CG  1 
ATOM 5110 C CD1 . LEU A 1 660  ? 91.782  130.895 117.757 1.00 115.12 ? 660  LEU A CD1 1 
ATOM 5111 C CD2 . LEU A 1 660  ? 90.136  129.144 118.422 1.00 132.46 ? 660  LEU A CD2 1 
ATOM 5112 N N   . MET A 1 661  ? 88.044  133.455 115.639 1.00 113.96 ? 661  MET A N   1 
ATOM 5113 C CA  . MET A 1 661  ? 87.602  133.660 114.271 1.00 112.77 ? 661  MET A CA  1 
ATOM 5114 C C   . MET A 1 661  ? 88.504  134.672 113.571 1.00 109.06 ? 661  MET A C   1 
ATOM 5115 O O   . MET A 1 661  ? 88.792  134.509 112.390 1.00 111.19 ? 661  MET A O   1 
ATOM 5116 C CB  . MET A 1 661  ? 86.145  134.125 114.202 1.00 120.67 ? 661  MET A CB  1 
ATOM 5117 C CG  . MET A 1 661  ? 85.185  132.975 114.063 1.00 132.29 ? 661  MET A CG  1 
ATOM 5118 S SD  . MET A 1 661  ? 85.637  131.919 112.664 1.00 160.75 ? 661  MET A SD  1 
ATOM 5119 C CE  . MET A 1 661  ? 84.027  131.282 112.206 1.00 179.37 ? 661  MET A CE  1 
ATOM 5120 N N   . ARG A 1 662  ? 88.982  135.686 114.304 1.00 109.98 ? 662  ARG A N   1 
ATOM 5121 C CA  . ARG A 1 662  ? 89.767  136.743 113.688 1.00 118.59 ? 662  ARG A CA  1 
ATOM 5122 C C   . ARG A 1 662  ? 91.066  136.194 113.097 1.00 116.48 ? 662  ARG A C   1 
ATOM 5123 O O   . ARG A 1 662  ? 91.437  136.602 112.003 1.00 131.23 ? 662  ARG A O   1 
ATOM 5124 C CB  . ARG A 1 662  ? 90.064  137.880 114.669 1.00 137.36 ? 662  ARG A CB  1 
ATOM 5125 C CG  . ARG A 1 662  ? 88.842  138.693 115.070 1.00 154.41 ? 662  ARG A CG  1 
ATOM 5126 C CD  . ARG A 1 662  ? 89.240  139.859 115.956 1.00 166.47 ? 662  ARG A CD  1 
ATOM 5127 N NE  . ARG A 1 662  ? 88.106  140.656 116.396 1.00 176.95 ? 662  ARG A NE  1 
ATOM 5128 C CZ  . ARG A 1 662  ? 87.144  140.224 117.205 1.00 193.49 ? 662  ARG A CZ  1 
ATOM 5129 N NH1 . ARG A 1 662  ? 87.162  138.984 117.664 1.00 200.52 ? 662  ARG A NH1 1 
ATOM 5130 N NH2 . ARG A 1 662  ? 86.162  141.038 117.553 1.00 201.81 ? 662  ARG A NH2 1 
ATOM 5131 N N   . ILE A 1 663  ? 91.787  135.312 113.798 1.00 107.85 ? 663  ILE A N   1 
ATOM 5132 C CA  . ILE A 1 663  ? 92.955  134.723 113.162 1.00 106.98 ? 663  ILE A CA  1 
ATOM 5133 C C   . ILE A 1 663  ? 92.426  133.547 112.361 1.00 119.61 ? 663  ILE A C   1 
ATOM 5134 O O   . ILE A 1 663  ? 91.823  132.652 112.938 1.00 127.17 ? 663  ILE A O   1 
ATOM 5135 C CB  . ILE A 1 663  ? 94.064  134.308 114.147 1.00 100.38 ? 663  ILE A CB  1 
ATOM 5136 C CG1 . ILE A 1 663  ? 94.457  135.457 115.076 1.00 108.64 ? 663  ILE A CG1 1 
ATOM 5137 C CG2 . ILE A 1 663  ? 95.269  133.765 113.390 1.00 97.84  ? 663  ILE A CG2 1 
ATOM 5138 C CD1 . ILE A 1 663  ? 95.662  135.173 115.947 1.00 109.79 ? 663  ILE A CD1 1 
ATOM 5139 N N   . PRO A 1 664  ? 92.556  133.544 111.019 1.00 130.07 ? 664  PRO A N   1 
ATOM 5140 C CA  . PRO A 1 664  ? 91.905  132.524 110.201 1.00 128.46 ? 664  PRO A CA  1 
ATOM 5141 C C   . PRO A 1 664  ? 92.736  131.289 109.859 1.00 118.97 ? 664  PRO A C   1 
ATOM 5142 O O   . PRO A 1 664  ? 92.180  130.299 109.394 1.00 116.14 ? 664  PRO A O   1 
ATOM 5143 C CB  . PRO A 1 664  ? 91.622  133.327 108.934 1.00 139.09 ? 664  PRO A CB  1 
ATOM 5144 C CG  . PRO A 1 664  ? 92.880  134.163 108.786 1.00 144.16 ? 664  PRO A CG  1 
ATOM 5145 C CD  . PRO A 1 664  ? 93.274  134.538 110.204 1.00 136.39 ? 664  PRO A CD  1 
ATOM 5146 N N   . ARG A 1 665  ? 94.060  131.348 110.060 1.00 107.20 ? 665  ARG A N   1 
ATOM 5147 C CA  . ARG A 1 665  ? 94.903  130.203 109.763 1.00 106.91 ? 665  ARG A CA  1 
ATOM 5148 C C   . ARG A 1 665  ? 94.309  128.995 110.480 1.00 115.74 ? 665  ARG A C   1 
ATOM 5149 O O   . ARG A 1 665  ? 94.001  129.078 111.666 1.00 127.22 ? 665  ARG A O   1 
ATOM 5150 C CB  . ARG A 1 665  ? 96.343  130.413 110.230 1.00 109.26 ? 665  ARG A CB  1 
ATOM 5151 C CG  . ARG A 1 665  ? 97.044  131.625 109.632 1.00 124.63 ? 665  ARG A CG  1 
ATOM 5152 C CD  . ARG A 1 665  ? 98.427  131.774 110.226 1.00 143.29 ? 665  ARG A CD  1 
ATOM 5153 N NE  . ARG A 1 665  ? 98.340  131.645 111.674 1.00 168.17 ? 665  ARG A NE  1 
ATOM 5154 C CZ  . ARG A 1 665  ? 98.724  132.553 112.561 1.00 192.52 ? 665  ARG A CZ  1 
ATOM 5155 N NH1 . ARG A 1 665  ? 99.252  133.700 112.175 1.00 198.20 ? 665  ARG A NH1 1 
ATOM 5156 N NH2 . ARG A 1 665  ? 98.591  132.300 113.851 1.00 196.97 ? 665  ARG A NH2 1 
ATOM 5157 N N   . ASP A 1 666  ? 94.126  127.888 109.752 1.00 120.69 ? 666  ASP A N   1 
ATOM 5158 C CA  . ASP A 1 666  ? 93.604  126.660 110.330 1.00 119.55 ? 666  ASP A CA  1 
ATOM 5159 C C   . ASP A 1 666  ? 94.702  126.070 111.212 1.00 112.26 ? 666  ASP A C   1 
ATOM 5160 O O   . ASP A 1 666  ? 95.865  126.100 110.825 1.00 107.24 ? 666  ASP A O   1 
ATOM 5161 C CB  . ASP A 1 666  ? 93.147  125.717 109.213 1.00 126.68 ? 666  ASP A CB  1 
ATOM 5162 C CG  . ASP A 1 666  ? 92.421  124.468 109.682 1.00 127.12 ? 666  ASP A CG  1 
ATOM 5163 O OD1 . ASP A 1 666  ? 93.025  123.686 110.442 1.00 127.62 ? 666  ASP A OD1 1 
ATOM 5164 O OD2 . ASP A 1 666  ? 91.261  124.277 109.264 1.00 119.77 ? 666  ASP A OD2 1 
ATOM 5165 N N   . GLY A 1 667  ? 94.341  125.576 112.403 1.00 110.61 ? 667  GLY A N   1 
ATOM 5166 C CA  . GLY A 1 667  ? 95.318  125.010 113.322 1.00 116.47 ? 667  GLY A CA  1 
ATOM 5167 C C   . GLY A 1 667  ? 95.839  126.018 114.349 1.00 115.23 ? 667  GLY A C   1 
ATOM 5168 O O   . GLY A 1 667  ? 96.901  125.816 114.934 1.00 113.55 ? 667  GLY A O   1 
ATOM 5169 N N   . ALA A 1 668  ? 95.082  127.093 114.592 1.00 110.70 ? 668  ALA A N   1 
ATOM 5170 C CA  . ALA A 1 668  ? 95.364  127.965 115.722 1.00 105.54 ? 668  ALA A CA  1 
ATOM 5171 C C   . ALA A 1 668  ? 94.560  127.482 116.929 1.00 101.00 ? 668  ALA A C   1 
ATOM 5172 O O   . ALA A 1 668  ? 93.462  126.968 116.748 1.00 89.47  ? 668  ALA A O   1 
ATOM 5173 C CB  . ALA A 1 668  ? 95.038  129.393 115.369 1.00 108.73 ? 668  ALA A CB  1 
ATOM 5174 N N   . PHE A 1 669  ? 95.108  127.666 118.144 1.00 96.20  ? 669  PHE A N   1 
ATOM 5175 C CA  . PHE A 1 669  ? 94.521  127.159 119.379 1.00 95.89  ? 669  PHE A CA  1 
ATOM 5176 C C   . PHE A 1 669  ? 94.709  128.172 120.507 1.00 105.81 ? 669  PHE A C   1 
ATOM 5177 O O   . PHE A 1 669  ? 95.791  128.745 120.623 1.00 113.50 ? 669  PHE A O   1 
ATOM 5178 C CB  . PHE A 1 669  ? 95.221  125.874 119.833 1.00 96.71  ? 669  PHE A CB  1 
ATOM 5179 C CG  . PHE A 1 669  ? 96.678  126.079 120.168 1.00 86.39  ? 669  PHE A CG  1 
ATOM 5180 C CD1 . PHE A 1 669  ? 97.604  126.276 119.163 1.00 80.99  ? 669  PHE A CD1 1 
ATOM 5181 C CD2 . PHE A 1 669  ? 97.115  126.112 121.481 1.00 87.01  ? 669  PHE A CD2 1 
ATOM 5182 C CE1 . PHE A 1 669  ? 98.940  126.486 119.457 1.00 82.90  ? 669  PHE A CE1 1 
ATOM 5183 C CE2 . PHE A 1 669  ? 98.451  126.326 121.776 1.00 91.85  ? 669  PHE A CE2 1 
ATOM 5184 C CZ  . PHE A 1 669  ? 99.362  126.510 120.762 1.00 89.78  ? 669  PHE A CZ  1 
ATOM 5185 N N   . LEU A 1 670  ? 93.681  128.353 121.355 1.00 98.91  ? 670  LEU A N   1 
ATOM 5186 C CA  . LEU A 1 670  ? 93.798  129.168 122.558 1.00 98.58  ? 670  LEU A CA  1 
ATOM 5187 C C   . LEU A 1 670  ? 93.441  128.326 123.782 1.00 103.25 ? 670  LEU A C   1 
ATOM 5188 O O   . LEU A 1 670  ? 92.471  127.574 123.753 1.00 103.46 ? 670  LEU A O   1 
ATOM 5189 C CB  . LEU A 1 670  ? 92.883  130.390 122.436 1.00 104.53 ? 670  LEU A CB  1 
ATOM 5190 C CG  . LEU A 1 670  ? 91.380  130.104 122.407 1.00 122.41 ? 670  LEU A CG  1 
ATOM 5191 C CD1 . LEU A 1 670  ? 90.758  130.233 123.794 1.00 128.48 ? 670  LEU A CD1 1 
ATOM 5192 C CD2 . LEU A 1 670  ? 90.662  131.022 121.425 1.00 131.03 ? 670  LEU A CD2 1 
ATOM 5193 N N   . ILE A 1 671  ? 94.224  128.464 124.862 1.00 103.37 ? 671  ILE A N   1 
ATOM 5194 C CA  . ILE A 1 671  ? 94.003  127.711 126.092 1.00 96.38  ? 671  ILE A CA  1 
ATOM 5195 C C   . ILE A 1 671  ? 93.403  128.641 127.145 1.00 85.29  ? 671  ILE A C   1 
ATOM 5196 O O   . ILE A 1 671  ? 94.027  129.625 127.523 1.00 80.83  ? 671  ILE A O   1 
ATOM 5197 C CB  . ILE A 1 671  ? 95.320  127.065 126.566 1.00 97.40  ? 671  ILE A CB  1 
ATOM 5198 C CG1 . ILE A 1 671  ? 95.660  125.821 125.740 1.00 101.18 ? 671  ILE A CG1 1 
ATOM 5199 C CG2 . ILE A 1 671  ? 95.275  126.744 128.055 1.00 104.91 ? 671  ILE A CG2 1 
ATOM 5200 C CD1 . ILE A 1 671  ? 94.807  124.608 126.065 1.00 101.09 ? 671  ILE A CD1 1 
ATOM 5201 N N   . ARG A 1 672  ? 92.209  128.302 127.641 1.00 75.58  ? 672  ARG A N   1 
ATOM 5202 C CA  . ARG A 1 672  ? 91.437  129.231 128.449 1.00 77.88  ? 672  ARG A CA  1 
ATOM 5203 C C   . ARG A 1 672  ? 90.971  128.586 129.749 1.00 88.28  ? 672  ARG A C   1 
ATOM 5204 O O   . ARG A 1 672  ? 90.242  127.607 129.700 1.00 98.34  ? 672  ARG A O   1 
ATOM 5205 C CB  . ARG A 1 672  ? 90.215  129.695 127.655 1.00 76.92  ? 672  ARG A CB  1 
ATOM 5206 C CG  . ARG A 1 672  ? 89.267  128.598 127.193 1.00 75.23  ? 672  ARG A CG  1 
ATOM 5207 C CD  . ARG A 1 672  ? 88.184  129.295 126.394 1.00 85.01  ? 672  ARG A CD  1 
ATOM 5208 N NE  . ARG A 1 672  ? 87.158  128.428 125.840 1.00 94.87  ? 672  ARG A NE  1 
ATOM 5209 C CZ  . ARG A 1 672  ? 86.223  127.817 126.556 1.00 110.03 ? 672  ARG A CZ  1 
ATOM 5210 N NH1 . ARG A 1 672  ? 86.234  127.922 127.874 1.00 114.39 ? 672  ARG A NH1 1 
ATOM 5211 N NH2 . ARG A 1 672  ? 85.290  127.096 125.952 1.00 112.38 ? 672  ARG A NH2 1 
ATOM 5212 N N   . LYS A 1 673  ? 91.312  129.147 130.917 1.00 89.37  ? 673  LYS A N   1 
ATOM 5213 C CA  . LYS A 1 673  ? 90.734  128.620 132.143 1.00 89.31  ? 673  LYS A CA  1 
ATOM 5214 C C   . LYS A 1 673  ? 89.219  128.699 132.022 1.00 92.67  ? 673  LYS A C   1 
ATOM 5215 O O   . LYS A 1 673  ? 88.688  129.763 131.728 1.00 99.66  ? 673  LYS A O   1 
ATOM 5216 C CB  . LYS A 1 673  ? 91.099  129.432 133.383 1.00 96.03  ? 673  LYS A CB  1 
ATOM 5217 C CG  . LYS A 1 673  ? 90.390  129.018 134.673 1.00 108.04 ? 673  LYS A CG  1 
ATOM 5218 C CD  . LYS A 1 673  ? 90.756  127.646 135.250 1.00 118.02 ? 673  LYS A CD  1 
ATOM 5219 C CE  . LYS A 1 673  ? 92.137  127.568 135.872 1.00 125.14 ? 673  LYS A CE  1 
ATOM 5220 N NZ  . LYS A 1 673  ? 93.212  127.737 134.868 1.00 127.95 ? 673  LYS A NZ  1 
ATOM 5221 N N   . ARG A 1 674  ? 88.528  127.584 132.257 1.00 100.04 ? 674  ARG A N   1 
ATOM 5222 C CA  . ARG A 1 674  ? 87.081  127.633 132.320 1.00 113.37 ? 674  ARG A CA  1 
ATOM 5223 C C   . ARG A 1 674  ? 86.734  128.401 133.588 1.00 133.41 ? 674  ARG A C   1 
ATOM 5224 O O   . ARG A 1 674  ? 87.438  128.284 134.584 1.00 124.19 ? 674  ARG A O   1 
ATOM 5225 C CB  . ARG A 1 674  ? 86.476  126.228 132.311 1.00 118.51 ? 674  ARG A CB  1 
ATOM 5226 C CG  . ARG A 1 674  ? 84.956  126.212 132.288 1.00 127.91 ? 674  ARG A CG  1 
ATOM 5227 C CD  . ARG A 1 674  ? 84.418  124.796 132.263 1.00 132.25 ? 674  ARG A CD  1 
ATOM 5228 N NE  . ARG A 1 674  ? 84.766  124.087 131.042 1.00 127.57 ? 674  ARG A NE  1 
ATOM 5229 C CZ  . ARG A 1 674  ? 83.883  123.623 130.166 1.00 134.95 ? 674  ARG A CZ  1 
ATOM 5230 N NH1 . ARG A 1 674  ? 84.295  122.970 129.095 1.00 144.57 ? 674  ARG A NH1 1 
ATOM 5231 N NH2 . ARG A 1 674  ? 82.587  123.797 130.364 1.00 134.84 ? 674  ARG A NH2 1 
ATOM 5232 N N   . GLU A 1 675  ? 85.679  129.217 133.520 1.00 164.87 ? 675  GLU A N   1 
ATOM 5233 C CA  . GLU A 1 675  ? 85.233  129.973 134.677 1.00 185.14 ? 675  GLU A CA  1 
ATOM 5234 C C   . GLU A 1 675  ? 84.648  129.011 135.703 1.00 179.83 ? 675  GLU A C   1 
ATOM 5235 O O   . GLU A 1 675  ? 84.018  128.021 135.334 1.00 167.27 ? 675  GLU A O   1 
ATOM 5236 C CB  . GLU A 1 675  ? 84.188  131.018 134.284 1.00 211.18 ? 675  GLU A CB  1 
ATOM 5237 C CG  . GLU A 1 675  ? 84.737  132.112 133.386 1.00 233.38 ? 675  GLU A CG  1 
ATOM 5238 C CD  . GLU A 1 675  ? 83.758  133.233 133.081 1.00 250.02 ? 675  GLU A CD  1 
ATOM 5239 O OE1 . GLU A 1 675  ? 84.062  134.392 133.429 1.00 254.29 ? 675  GLU A OE1 1 
ATOM 5240 O OE2 . GLU A 1 675  ? 82.695  132.946 132.494 1.00 262.22 ? 675  GLU A OE2 1 
ATOM 5241 N N   . GLY A 1 676  ? 84.894  129.314 136.983 1.00 189.66 ? 676  GLY A N   1 
ATOM 5242 C CA  . GLY A 1 676  ? 84.228  128.652 138.092 1.00 199.73 ? 676  GLY A CA  1 
ATOM 5243 C C   . GLY A 1 676  ? 84.731  127.233 138.343 1.00 200.26 ? 676  GLY A C   1 
ATOM 5244 O O   . GLY A 1 676  ? 84.052  126.444 138.999 1.00 213.52 ? 676  GLY A O   1 
ATOM 5245 N N   . SER A 1 677  ? 85.919  126.892 137.843 1.00 194.37 ? 677  SER A N   1 
ATOM 5246 C CA  . SER A 1 677  ? 86.432  125.562 138.117 1.00 197.19 ? 677  SER A CA  1 
ATOM 5247 C C   . SER A 1 677  ? 87.952  125.522 138.030 1.00 197.50 ? 677  SER A C   1 
ATOM 5248 O O   . SER A 1 677  ? 88.611  126.534 137.803 1.00 200.62 ? 677  SER A O   1 
ATOM 5249 C CB  . SER A 1 677  ? 85.809  124.542 137.199 1.00 193.32 ? 677  SER A CB  1 
ATOM 5250 O OG  . SER A 1 677  ? 86.270  123.242 137.534 1.00 185.93 ? 677  SER A OG  1 
ATOM 5251 N N   . ASP A 1 678  ? 88.490  124.318 138.247 1.00 185.65 ? 678  ASP A N   1 
ATOM 5252 C CA  . ASP A 1 678  ? 89.900  124.049 138.046 1.00 175.10 ? 678  ASP A CA  1 
ATOM 5253 C C   . ASP A 1 678  ? 90.154  123.790 136.560 1.00 159.01 ? 678  ASP A C   1 
ATOM 5254 O O   . ASP A 1 678  ? 91.223  124.128 136.069 1.00 163.33 ? 678  ASP A O   1 
ATOM 5255 C CB  . ASP A 1 678  ? 90.358  122.882 138.925 1.00 185.23 ? 678  ASP A CB  1 
ATOM 5256 C CG  . ASP A 1 678  ? 91.850  122.864 139.216 1.00 190.46 ? 678  ASP A CG  1 
ATOM 5257 O OD1 . ASP A 1 678  ? 92.562  123.753 138.707 1.00 185.06 ? 678  ASP A OD1 1 
ATOM 5258 O OD2 . ASP A 1 678  ? 92.287  121.964 139.962 1.00 201.00 ? 678  ASP A OD2 1 
ATOM 5259 N N   . SER A 1 679  ? 89.134  123.284 135.849 1.00 133.56 ? 679  SER A N   1 
ATOM 5260 C CA  . SER A 1 679  ? 89.229  122.675 134.524 1.00 117.53 ? 679  SER A CA  1 
ATOM 5261 C C   . SER A 1 679  ? 89.640  123.621 133.387 1.00 94.26  ? 679  SER A C   1 
ATOM 5262 O O   . SER A 1 679  ? 88.797  124.299 132.809 1.00 95.88  ? 679  SER A O   1 
ATOM 5263 C CB  . SER A 1 679  ? 87.887  122.090 134.198 1.00 121.00 ? 679  SER A CB  1 
ATOM 5264 O OG  . SER A 1 679  ? 86.903  123.115 134.235 1.00 120.88 ? 679  SER A OG  1 
ATOM 5265 N N   . TYR A 1 680  ? 90.887  123.516 132.923 1.00 73.83  ? 680  TYR A N   1 
ATOM 5266 C CA  . TYR A 1 680  ? 91.359  124.273 131.777 1.00 71.03  ? 680  TYR A CA  1 
ATOM 5267 C C   . TYR A 1 680  ? 90.611  123.748 130.542 1.00 74.67  ? 680  TYR A C   1 
ATOM 5268 O O   . TYR A 1 680  ? 90.214  122.591 130.569 1.00 83.40  ? 680  TYR A O   1 
ATOM 5269 C CB  . TYR A 1 680  ? 92.877  124.093 131.681 1.00 75.32  ? 680  TYR A CB  1 
ATOM 5270 C CG  . TYR A 1 680  ? 93.674  124.483 132.903 1.00 88.51  ? 680  TYR A CG  1 
ATOM 5271 C CD1 . TYR A 1 680  ? 93.401  123.973 134.162 1.00 99.75  ? 680  TYR A CD1 1 
ATOM 5272 C CD2 . TYR A 1 680  ? 94.764  125.332 132.787 1.00 110.27 ? 680  TYR A CD2 1 
ATOM 5273 C CE1 . TYR A 1 680  ? 94.157  124.324 135.272 1.00 124.51 ? 680  TYR A CE1 1 
ATOM 5274 C CE2 . TYR A 1 680  ? 95.540  125.685 133.880 1.00 128.40 ? 680  TYR A CE2 1 
ATOM 5275 C CZ  . TYR A 1 680  ? 95.232  125.185 135.133 1.00 139.53 ? 680  TYR A CZ  1 
ATOM 5276 O OH  . TYR A 1 680  ? 95.973  125.558 136.231 1.00 154.80 ? 680  TYR A OH  1 
ATOM 5277 N N   . ALA A 1 681  ? 90.407  124.547 129.471 1.00 79.44  ? 681  ALA A N   1 
ATOM 5278 C CA  . ALA A 1 681  ? 89.844  124.065 128.201 1.00 82.42  ? 681  ALA A CA  1 
ATOM 5279 C C   . ALA A 1 681  ? 90.633  124.599 126.998 1.00 90.59  ? 681  ALA A C   1 
ATOM 5280 O O   . ALA A 1 681  ? 91.352  125.589 127.117 1.00 87.65  ? 681  ALA A O   1 
ATOM 5281 C CB  . ALA A 1 681  ? 88.388  124.446 128.074 1.00 79.96  ? 681  ALA A CB  1 
ATOM 5282 N N   . ILE A 1 682  ? 90.463  123.955 125.830 1.00 96.23  ? 682  ILE A N   1 
ATOM 5283 C CA  . ILE A 1 682  ? 91.249  124.261 124.638 1.00 99.01  ? 682  ILE A CA  1 
ATOM 5284 C C   . ILE A 1 682  ? 90.317  124.561 123.465 1.00 111.00 ? 682  ILE A C   1 
ATOM 5285 O O   . ILE A 1 682  ? 89.407  123.779 123.188 1.00 103.92 ? 682  ILE A O   1 
ATOM 5286 C CB  . ILE A 1 682  ? 92.216  123.109 124.292 1.00 95.06  ? 682  ILE A CB  1 
ATOM 5287 C CG1 . ILE A 1 682  ? 93.282  123.545 123.283 1.00 97.78  ? 682  ILE A CG1 1 
ATOM 5288 C CG2 . ILE A 1 682  ? 91.464  121.875 123.805 1.00 91.97  ? 682  ILE A CG2 1 
ATOM 5289 C CD1 . ILE A 1 682  ? 94.428  122.571 123.156 1.00 109.13 ? 682  ILE A CD1 1 
ATOM 5290 N N   . THR A 1 683  ? 90.558  125.699 122.786 1.00 120.31 ? 683  THR A N   1 
ATOM 5291 C CA  . THR A 1 683  ? 89.862  126.043 121.554 1.00 117.59 ? 683  THR A CA  1 
ATOM 5292 C C   . THR A 1 683  ? 90.877  126.231 120.428 1.00 110.67 ? 683  THR A C   1 
ATOM 5293 O O   . THR A 1 683  ? 91.845  126.973 120.573 1.00 90.42  ? 683  THR A O   1 
ATOM 5294 C CB  . THR A 1 683  ? 89.002  127.306 121.696 1.00 120.37 ? 683  THR A CB  1 
ATOM 5295 O OG1 . THR A 1 683  ? 88.278  127.256 122.924 1.00 123.82 ? 683  THR A OG1 1 
ATOM 5296 C CG2 . THR A 1 683  ? 88.022  127.474 120.555 1.00 123.57 ? 683  THR A CG2 1 
ATOM 5297 N N   . PHE A 1 684  ? 90.610  125.548 119.309 1.00 105.98 ? 684  PHE A N   1 
ATOM 5298 C CA  . PHE A 1 684  ? 91.409  125.611 118.099 1.00 95.01  ? 684  PHE A CA  1 
ATOM 5299 C C   . PHE A 1 684  ? 90.476  125.929 116.937 1.00 100.49 ? 684  PHE A C   1 
ATOM 5300 O O   . PHE A 1 684  ? 89.267  125.748 117.055 1.00 97.57  ? 684  PHE A O   1 
ATOM 5301 C CB  . PHE A 1 684  ? 92.119  124.274 117.862 1.00 92.10  ? 684  PHE A CB  1 
ATOM 5302 C CG  . PHE A 1 684  ? 91.200  123.075 117.852 1.00 83.58  ? 684  PHE A CG  1 
ATOM 5303 C CD1 . PHE A 1 684  ? 90.168  122.970 116.932 1.00 79.29  ? 684  PHE A CD1 1 
ATOM 5304 C CD2 . PHE A 1 684  ? 91.344  122.063 118.781 1.00 82.92  ? 684  PHE A CD2 1 
ATOM 5305 C CE1 . PHE A 1 684  ? 89.309  121.886 116.932 1.00 74.61  ? 684  PHE A CE1 1 
ATOM 5306 C CE2 . PHE A 1 684  ? 90.482  120.978 118.780 1.00 84.13  ? 684  PHE A CE2 1 
ATOM 5307 C CZ  . PHE A 1 684  ? 89.468  120.890 117.856 1.00 77.59  ? 684  PHE A CZ  1 
ATOM 5308 N N   . ARG A 1 685  ? 91.042  126.358 115.807 1.00 100.63 ? 685  ARG A N   1 
ATOM 5309 C CA  . ARG A 1 685  ? 90.242  126.639 114.631 1.00 105.98 ? 685  ARG A CA  1 
ATOM 5310 C C   . ARG A 1 685  ? 90.638  125.659 113.538 1.00 101.38 ? 685  ARG A C   1 
ATOM 5311 O O   . ARG A 1 685  ? 91.809  125.594 113.183 1.00 93.18  ? 685  ARG A O   1 
ATOM 5312 C CB  . ARG A 1 685  ? 90.483  128.075 114.166 1.00 125.49 ? 685  ARG A CB  1 
ATOM 5313 C CG  . ARG A 1 685  ? 89.463  128.596 113.162 1.00 138.17 ? 685  ARG A CG  1 
ATOM 5314 C CD  . ARG A 1 685  ? 89.543  128.067 111.735 1.00 141.41 ? 685  ARG A CD  1 
ATOM 5315 N NE  . ARG A 1 685  ? 88.623  128.784 110.861 1.00 130.00 ? 685  ARG A NE  1 
ATOM 5316 C CZ  . ARG A 1 685  ? 88.668  130.092 110.624 1.00 119.74 ? 685  ARG A CZ  1 
ATOM 5317 N NH1 . ARG A 1 685  ? 89.636  130.828 111.136 1.00 105.57 ? 685  ARG A NH1 1 
ATOM 5318 N NH2 . ARG A 1 685  ? 87.743  130.663 109.874 1.00 128.92 ? 685  ARG A NH2 1 
ATOM 5319 N N   . ALA A 1 686  ? 89.655  124.920 113.014 1.00 104.34 ? 686  ALA A N   1 
ATOM 5320 C CA  . ALA A 1 686  ? 89.898  124.017 111.904 1.00 113.92 ? 686  ALA A CA  1 
ATOM 5321 C C   . ALA A 1 686  ? 88.653  123.913 111.032 1.00 127.71 ? 686  ALA A C   1 
ATOM 5322 O O   . ALA A 1 686  ? 87.536  124.015 111.531 1.00 133.11 ? 686  ALA A O   1 
ATOM 5323 C CB  . ALA A 1 686  ? 90.316  122.665 112.418 1.00 113.63 ? 686  ALA A CB  1 
ATOM 5324 N N   . ARG A 1 687  ? 88.862  123.707 109.727 1.00 140.97 ? 687  ARG A N   1 
ATOM 5325 C CA  . ARG A 1 687  ? 87.768  123.553 108.782 1.00 158.18 ? 687  ARG A CA  1 
ATOM 5326 C C   . ARG A 1 687  ? 86.734  124.650 109.031 1.00 148.04 ? 687  ARG A C   1 
ATOM 5327 O O   . ARG A 1 687  ? 85.540  124.376 109.148 1.00 134.03 ? 687  ARG A O   1 
ATOM 5328 C CB  . ARG A 1 687  ? 87.175  122.145 108.914 1.00 182.11 ? 687  ARG A CB  1 
ATOM 5329 C CG  . ARG A 1 687  ? 86.155  121.770 107.846 1.00 199.59 ? 687  ARG A CG  1 
ATOM 5330 C CD  . ARG A 1 687  ? 86.629  122.028 106.427 1.00 211.51 ? 687  ARG A CD  1 
ATOM 5331 N NE  . ARG A 1 687  ? 87.927  121.422 106.147 1.00 217.86 ? 687  ARG A NE  1 
ATOM 5332 C CZ  . ARG A 1 687  ? 88.158  120.511 105.204 1.00 224.92 ? 687  ARG A CZ  1 
ATOM 5333 N NH1 . ARG A 1 687  ? 87.181  120.099 104.416 1.00 225.48 ? 687  ARG A NH1 1 
ATOM 5334 N NH2 . ARG A 1 687  ? 89.375  120.019 105.049 1.00 228.82 ? 687  ARG A NH2 1 
ATOM 5335 N N   . GLY A 1 688  ? 87.214  125.895 109.147 1.00 150.79 ? 688  GLY A N   1 
ATOM 5336 C CA  . GLY A 1 688  ? 86.337  127.039 109.332 1.00 156.53 ? 688  GLY A CA  1 
ATOM 5337 C C   . GLY A 1 688  ? 85.746  127.087 110.739 1.00 156.83 ? 688  GLY A C   1 
ATOM 5338 O O   . GLY A 1 688  ? 85.912  128.071 111.456 1.00 163.91 ? 688  GLY A O   1 
ATOM 5339 N N   . LYS A 1 689  ? 85.039  126.014 111.109 1.00 152.57 ? 689  LYS A N   1 
ATOM 5340 C CA  . LYS A 1 689  ? 84.360  125.934 112.391 1.00 157.12 ? 689  LYS A CA  1 
ATOM 5341 C C   . LYS A 1 689  ? 85.391  126.066 113.510 1.00 147.60 ? 689  LYS A C   1 
ATOM 5342 O O   . LYS A 1 689  ? 86.530  125.629 113.366 1.00 150.84 ? 689  LYS A O   1 
ATOM 5343 C CB  . LYS A 1 689  ? 83.595  124.611 112.506 1.00 167.64 ? 689  LYS A CB  1 
ATOM 5344 C CG  . LYS A 1 689  ? 82.701  124.268 111.320 1.00 185.64 ? 689  LYS A CG  1 
ATOM 5345 C CD  . LYS A 1 689  ? 81.954  122.961 111.487 1.00 202.72 ? 689  LYS A CD  1 
ATOM 5346 C CE  . LYS A 1 689  ? 81.129  122.590 110.272 1.00 210.03 ? 689  LYS A CE  1 
ATOM 5347 N NZ  . LYS A 1 689  ? 80.430  121.295 110.457 1.00 211.09 ? 689  LYS A NZ  1 
ATOM 5348 N N   . VAL A 1 690  ? 84.988  126.692 114.616 1.00 125.88 ? 690  VAL A N   1 
ATOM 5349 C CA  . VAL A 1 690  ? 85.801  126.701 115.819 1.00 114.93 ? 690  VAL A CA  1 
ATOM 5350 C C   . VAL A 1 690  ? 85.160  125.729 116.802 1.00 127.82 ? 690  VAL A C   1 
ATOM 5351 O O   . VAL A 1 690  ? 84.002  125.903 117.176 1.00 135.70 ? 690  VAL A O   1 
ATOM 5352 C CB  . VAL A 1 690  ? 85.968  128.110 116.423 1.00 112.59 ? 690  VAL A CB  1 
ATOM 5353 C CG1 . VAL A 1 690  ? 87.378  128.649 116.238 1.00 112.89 ? 690  VAL A CG1 1 
ATOM 5354 C CG2 . VAL A 1 690  ? 84.946  129.100 115.886 1.00 120.86 ? 690  VAL A CG2 1 
ATOM 5355 N N   . LYS A 1 691  ? 85.924  124.692 117.171 1.00 135.79 ? 691  LYS A N   1 
ATOM 5356 C CA  . LYS A 1 691  ? 85.469  123.646 118.073 1.00 137.27 ? 691  LYS A CA  1 
ATOM 5357 C C   . LYS A 1 691  ? 86.411  123.598 119.270 1.00 138.82 ? 691  LYS A C   1 
ATOM 5358 O O   . LYS A 1 691  ? 87.626  123.640 119.098 1.00 126.94 ? 691  LYS A O   1 
ATOM 5359 C CB  . LYS A 1 691  ? 85.453  122.284 117.371 1.00 134.36 ? 691  LYS A CB  1 
ATOM 5360 C CG  . LYS A 1 691  ? 84.727  122.246 116.032 1.00 136.13 ? 691  LYS A CG  1 
ATOM 5361 C CD  . LYS A 1 691  ? 84.967  120.979 115.227 1.00 136.82 ? 691  LYS A CD  1 
ATOM 5362 C CE  . LYS A 1 691  ? 84.034  119.839 115.577 1.00 138.69 ? 691  LYS A CE  1 
ATOM 5363 N NZ  . LYS A 1 691  ? 84.266  119.321 116.947 1.00 142.92 ? 691  LYS A NZ  1 
ATOM 5364 N N   . HIS A 1 692  ? 85.834  123.477 120.470 1.00 140.81 ? 692  HIS A N   1 
ATOM 5365 C CA  . HIS A 1 692  ? 86.604  123.480 121.704 1.00 142.07 ? 692  HIS A CA  1 
ATOM 5366 C C   . HIS A 1 692  ? 86.282  122.211 122.492 1.00 144.66 ? 692  HIS A C   1 
ATOM 5367 O O   . HIS A 1 692  ? 85.117  121.838 122.626 1.00 144.87 ? 692  HIS A O   1 
ATOM 5368 C CB  . HIS A 1 692  ? 86.470  124.810 122.468 1.00 135.45 ? 692  HIS A CB  1 
ATOM 5369 C CG  . HIS A 1 692  ? 85.263  125.658 122.211 1.00 136.06 ? 692  HIS A CG  1 
ATOM 5370 N ND1 . HIS A 1 692  ? 85.278  126.994 122.554 1.00 131.16 ? 692  HIS A ND1 1 
ATOM 5371 C CD2 . HIS A 1 692  ? 84.059  125.439 121.661 1.00 143.72 ? 692  HIS A CD2 1 
ATOM 5372 C CE1 . HIS A 1 692  ? 84.126  127.552 122.217 1.00 138.06 ? 692  HIS A CE1 1 
ATOM 5373 N NE2 . HIS A 1 692  ? 83.368  126.623 121.679 1.00 141.26 ? 692  HIS A NE2 1 
ATOM 5374 N N   . CYS A 1 693  ? 87.343  121.557 122.991 1.00 131.26 ? 693  CYS A N   1 
ATOM 5375 C CA  . CYS A 1 693  ? 87.249  120.254 123.631 1.00 118.53 ? 693  CYS A CA  1 
ATOM 5376 C C   . CYS A 1 693  ? 87.739  120.345 125.073 1.00 107.47 ? 693  CYS A C   1 
ATOM 5377 O O   . CYS A 1 693  ? 88.812  120.883 125.336 1.00 109.14 ? 693  CYS A O   1 
ATOM 5378 C CB  . CYS A 1 693  ? 88.073  119.226 122.871 1.00 126.07 ? 693  CYS A CB  1 
ATOM 5379 S SG  . CYS A 1 693  ? 87.823  117.529 123.451 1.00 156.65 ? 693  CYS A SG  1 
ATOM 5380 N N   . ARG A 1 694  ? 86.954  119.771 125.992 1.00 92.52  ? 694  ARG A N   1 
ATOM 5381 C CA  . ARG A 1 694  ? 87.089  120.028 127.416 1.00 87.87  ? 694  ARG A CA  1 
ATOM 5382 C C   . ARG A 1 694  ? 88.260  119.252 128.011 1.00 73.06  ? 694  ARG A C   1 
ATOM 5383 O O   . ARG A 1 694  ? 88.295  118.035 127.900 1.00 81.67  ? 694  ARG A O   1 
ATOM 5384 C CB  . ARG A 1 694  ? 85.793  119.602 128.107 1.00 101.75 ? 694  ARG A CB  1 
ATOM 5385 C CG  . ARG A 1 694  ? 85.771  119.825 129.612 1.00 117.35 ? 694  ARG A CG  1 
ATOM 5386 C CD  . ARG A 1 694  ? 84.473  119.316 130.216 1.00 127.58 ? 694  ARG A CD  1 
ATOM 5387 N NE  . ARG A 1 694  ? 83.292  119.902 129.588 1.00 135.49 ? 694  ARG A NE  1 
ATOM 5388 C CZ  . ARG A 1 694  ? 82.382  120.640 130.215 1.00 146.55 ? 694  ARG A CZ  1 
ATOM 5389 N NH1 . ARG A 1 694  ? 82.475  120.849 131.516 1.00 150.51 ? 694  ARG A NH1 1 
ATOM 5390 N NH2 . ARG A 1 694  ? 81.371  121.157 129.538 1.00 147.47 ? 694  ARG A NH2 1 
ATOM 5391 N N   . ILE A 1 695  ? 89.175  119.946 128.697 1.00 58.85  ? 695  ILE A N   1 
ATOM 5392 C CA  . ILE A 1 695  ? 90.247  119.292 129.430 1.00 55.84  ? 695  ILE A CA  1 
ATOM 5393 C C   . ILE A 1 695  ? 89.836  119.191 130.897 1.00 69.18  ? 695  ILE A C   1 
ATOM 5394 O O   . ILE A 1 695  ? 89.735  120.206 131.570 1.00 80.32  ? 695  ILE A O   1 
ATOM 5395 C CB  . ILE A 1 695  ? 91.576  120.059 129.280 1.00 48.19  ? 695  ILE A CB  1 
ATOM 5396 C CG1 . ILE A 1 695  ? 92.157  119.929 127.873 1.00 50.50  ? 695  ILE A CG1 1 
ATOM 5397 C CG2 . ILE A 1 695  ? 92.585  119.633 130.341 1.00 46.91  ? 695  ILE A CG2 1 
ATOM 5398 C CD1 . ILE A 1 695  ? 93.523  120.579 127.706 1.00 54.01  ? 695  ILE A CD1 1 
ATOM 5399 N N   . ASN A 1 696  ? 89.601  117.972 131.398 1.00 78.32  ? 696  ASN A N   1 
ATOM 5400 C CA  . ASN A 1 696  ? 89.394  117.758 132.825 1.00 84.61  ? 696  ASN A CA  1 
ATOM 5401 C C   . ASN A 1 696  ? 90.752  117.571 133.504 1.00 89.51  ? 696  ASN A C   1 
ATOM 5402 O O   . ASN A 1 696  ? 91.761  117.386 132.827 1.00 93.84  ? 696  ASN A O   1 
ATOM 5403 C CB  . ASN A 1 696  ? 88.481  116.560 133.102 1.00 90.59  ? 696  ASN A CB  1 
ATOM 5404 C CG  . ASN A 1 696  ? 87.152  116.632 132.379 1.00 101.40 ? 696  ASN A CG  1 
ATOM 5405 O OD1 . ASN A 1 696  ? 86.904  117.545 131.594 1.00 102.85 ? 696  ASN A OD1 1 
ATOM 5406 N ND2 . ASN A 1 696  ? 86.289  115.661 132.631 1.00 112.94 ? 696  ASN A ND2 1 
ATOM 5407 N N   . ARG A 1 697  ? 90.771  117.587 134.844 1.00 89.32  ? 697  ARG A N   1 
ATOM 5408 C CA  . ARG A 1 697  ? 92.018  117.482 135.587 1.00 94.61  ? 697  ARG A CA  1 
ATOM 5409 C C   . ARG A 1 697  ? 91.838  116.588 136.813 1.00 116.69 ? 697  ARG A C   1 
ATOM 5410 O O   . ARG A 1 697  ? 91.230  117.012 137.794 1.00 134.06 ? 697  ARG A O   1 
ATOM 5411 C CB  . ARG A 1 697  ? 92.498  118.874 136.009 1.00 93.27  ? 697  ARG A CB  1 
ATOM 5412 C CG  . ARG A 1 697  ? 93.814  118.870 136.771 1.00 96.74  ? 697  ARG A CG  1 
ATOM 5413 C CD  . ARG A 1 697  ? 94.283  120.265 137.126 1.00 105.58 ? 697  ARG A CD  1 
ATOM 5414 N NE  . ARG A 1 697  ? 95.691  120.315 137.502 1.00 116.04 ? 697  ARG A NE  1 
ATOM 5415 C CZ  . ARG A 1 697  ? 96.353  121.431 137.796 1.00 132.52 ? 697  ARG A CZ  1 
ATOM 5416 N NH1 . ARG A 1 697  ? 95.727  122.597 137.781 1.00 137.73 ? 697  ARG A NH1 1 
ATOM 5417 N NH2 . ARG A 1 697  ? 97.642  121.382 138.094 1.00 134.39 ? 697  ARG A NH2 1 
ATOM 5418 N N   . ASP A 1 698  ? 92.432  115.382 136.757 1.00 136.81 ? 698  ASP A N   1 
ATOM 5419 C CA  . ASP A 1 698  ? 92.415  114.393 137.831 1.00 146.30 ? 698  ASP A CA  1 
ATOM 5420 C C   . ASP A 1 698  ? 93.836  114.175 138.364 1.00 134.94 ? 698  ASP A C   1 
ATOM 5421 O O   . ASP A 1 698  ? 94.651  113.536 137.702 1.00 125.68 ? 698  ASP A O   1 
ATOM 5422 C CB  . ASP A 1 698  ? 91.835  113.069 137.318 1.00 155.47 ? 698  ASP A CB  1 
ATOM 5423 C CG  . ASP A 1 698  ? 91.914  111.916 138.305 1.00 169.91 ? 698  ASP A CG  1 
ATOM 5424 O OD1 . ASP A 1 698  ? 91.262  112.008 139.367 1.00 181.92 ? 698  ASP A OD1 1 
ATOM 5425 O OD2 . ASP A 1 698  ? 92.623  110.934 137.999 1.00 170.22 ? 698  ASP A OD2 1 
ATOM 5426 N N   . GLY A 1 699  ? 94.129  114.687 139.569 1.00 126.69 ? 699  GLY A N   1 
ATOM 5427 C CA  . GLY A 1 699  ? 95.469  114.609 140.140 1.00 123.93 ? 699  GLY A CA  1 
ATOM 5428 C C   . GLY A 1 699  ? 96.431  115.499 139.363 1.00 123.81 ? 699  GLY A C   1 
ATOM 5429 O O   . GLY A 1 699  ? 95.984  116.381 138.645 1.00 122.91 ? 699  GLY A O   1 
ATOM 5430 N N   . ARG A 1 700  ? 97.744  115.278 139.467 1.00 134.16 ? 700  ARG A N   1 
ATOM 5431 C CA  . ARG A 1 700  ? 98.641  116.023 138.596 1.00 146.41 ? 700  ARG A CA  1 
ATOM 5432 C C   . ARG A 1 700  ? 98.620  115.354 137.220 1.00 144.07 ? 700  ARG A C   1 
ATOM 5433 O O   . ARG A 1 700  ? 99.630  114.850 136.752 1.00 142.50 ? 700  ARG A O   1 
ATOM 5434 C CB  . ARG A 1 700  ? 100.032 116.257 139.213 1.00 155.32 ? 700  ARG A CB  1 
ATOM 5435 C CG  . ARG A 1 700  ? 100.843 115.050 139.681 1.00 166.66 ? 700  ARG A CG  1 
ATOM 5436 C CD  . ARG A 1 700  ? 101.494 114.217 138.584 1.00 178.43 ? 700  ARG A CD  1 
ATOM 5437 N NE  . ARG A 1 700  ? 102.484 113.188 138.917 1.00 204.34 ? 700  ARG A NE  1 
ATOM 5438 C CZ  . ARG A 1 700  ? 102.986 112.910 140.120 1.00 240.19 ? 700  ARG A CZ  1 
ATOM 5439 N NH1 . ARG A 1 700  ? 102.620 113.587 141.194 1.00 250.03 ? 700  ARG A NH1 1 
ATOM 5440 N NH2 . ARG A 1 700  ? 103.874 111.936 140.245 1.00 254.63 ? 700  ARG A NH2 1 
ATOM 5441 N N   . HIS A 1 701  ? 97.453  115.389 136.568 1.00 138.99 ? 701  HIS A N   1 
ATOM 5442 C CA  . HIS A 1 701  ? 97.254  114.760 135.273 1.00 139.04 ? 701  HIS A CA  1 
ATOM 5443 C C   . HIS A 1 701  ? 96.121  115.478 134.540 1.00 129.11 ? 701  HIS A C   1 
ATOM 5444 O O   . HIS A 1 701  ? 95.038  115.628 135.088 1.00 144.93 ? 701  HIS A O   1 
ATOM 5445 C CB  . HIS A 1 701  ? 96.896  113.277 135.438 1.00 148.55 ? 701  HIS A CB  1 
ATOM 5446 C CG  . HIS A 1 701  ? 98.005  112.380 135.875 1.00 158.69 ? 701  HIS A CG  1 
ATOM 5447 N ND1 . HIS A 1 701  ? 99.328  112.760 135.944 1.00 164.57 ? 701  HIS A ND1 1 
ATOM 5448 C CD2 . HIS A 1 701  ? 97.975  111.084 136.214 1.00 170.40 ? 701  HIS A CD2 1 
ATOM 5449 C CE1 . HIS A 1 701  ? 100.059 111.728 136.341 1.00 177.74 ? 701  HIS A CE1 1 
ATOM 5450 N NE2 . HIS A 1 701  ? 99.257  110.698 136.510 1.00 182.19 ? 701  HIS A NE2 1 
ATOM 5451 N N   . PHE A 1 702  ? 96.373  115.921 133.304 1.00 98.17  ? 702  PHE A N   1 
ATOM 5452 C CA  . PHE A 1 702  ? 95.347  116.539 132.483 1.00 80.41  ? 702  PHE A CA  1 
ATOM 5453 C C   . PHE A 1 702  ? 94.783  115.471 131.554 1.00 66.36  ? 702  PHE A C   1 
ATOM 5454 O O   . PHE A 1 702  ? 95.545  114.750 130.921 1.00 70.15  ? 702  PHE A O   1 
ATOM 5455 C CB  . PHE A 1 702  ? 95.951  117.727 131.729 1.00 95.03  ? 702  PHE A CB  1 
ATOM 5456 C CG  . PHE A 1 702  ? 96.419  118.842 132.627 1.00 96.18  ? 702  PHE A CG  1 
ATOM 5457 C CD1 . PHE A 1 702  ? 95.485  119.621 133.286 1.00 102.62 ? 702  PHE A CD1 1 
ATOM 5458 C CD2 . PHE A 1 702  ? 97.770  119.112 132.817 1.00 90.91  ? 702  PHE A CD2 1 
ATOM 5459 C CE1 . PHE A 1 702  ? 95.892  120.656 134.110 1.00 108.27 ? 702  PHE A CE1 1 
ATOM 5460 C CE2 . PHE A 1 702  ? 98.172  120.142 133.652 1.00 93.40  ? 702  PHE A CE2 1 
ATOM 5461 C CZ  . PHE A 1 702  ? 97.232  120.911 134.292 1.00 102.28 ? 702  PHE A CZ  1 
ATOM 5462 N N   . VAL A 1 703  ? 93.457  115.357 131.481 1.00 64.38  ? 703  VAL A N   1 
ATOM 5463 C CA  . VAL A 1 703  ? 92.834  114.270 130.740 1.00 77.32  ? 703  VAL A CA  1 
ATOM 5464 C C   . VAL A 1 703  ? 92.023  114.833 129.577 1.00 76.15  ? 703  VAL A C   1 
ATOM 5465 O O   . VAL A 1 703  ? 90.850  115.153 129.739 1.00 77.88  ? 703  VAL A O   1 
ATOM 5466 C CB  . VAL A 1 703  ? 91.949  113.389 131.649 1.00 98.95  ? 703  VAL A CB  1 
ATOM 5467 C CG1 . VAL A 1 703  ? 92.755  112.343 132.410 1.00 106.62 ? 703  VAL A CG1 1 
ATOM 5468 C CG2 . VAL A 1 703  ? 91.103  114.218 132.607 1.00 111.67 ? 703  VAL A CG2 1 
ATOM 5469 N N   . LEU A 1 704  ? 92.635  114.935 128.393 1.00 75.98  ? 704  LEU A N   1 
ATOM 5470 C CA  . LEU A 1 704  ? 91.892  115.390 127.230 1.00 73.25  ? 704  LEU A CA  1 
ATOM 5471 C C   . LEU A 1 704  ? 91.068  114.226 126.697 1.00 68.30  ? 704  LEU A C   1 
ATOM 5472 O O   . LEU A 1 704  ? 91.624  113.236 126.235 1.00 75.11  ? 704  LEU A O   1 
ATOM 5473 C CB  . LEU A 1 704  ? 92.847  115.930 126.167 1.00 75.88  ? 704  LEU A CB  1 
ATOM 5474 C CG  . LEU A 1 704  ? 92.156  116.437 124.901 1.00 91.49  ? 704  LEU A CG  1 
ATOM 5475 C CD1 . LEU A 1 704  ? 91.155  117.553 125.201 1.00 103.20 ? 704  LEU A CD1 1 
ATOM 5476 C CD2 . LEU A 1 704  ? 93.176  116.913 123.886 1.00 97.47  ? 704  LEU A CD2 1 
ATOM 5477 N N   . GLY A 1 705  ? 89.743  114.359 126.771 1.00 68.03  ? 705  GLY A N   1 
ATOM 5478 C CA  . GLY A 1 705  ? 88.868  113.203 126.698 1.00 75.58  ? 705  GLY A CA  1 
ATOM 5479 C C   . GLY A 1 705  ? 89.129  112.275 127.879 1.00 79.26  ? 705  GLY A C   1 
ATOM 5480 O O   . GLY A 1 705  ? 89.762  112.686 128.850 1.00 80.71  ? 705  GLY A O   1 
ATOM 5481 N N   . THR A 1 706  ? 88.670  111.024 127.774 1.00 81.31  ? 706  THR A N   1 
ATOM 5482 C CA  . THR A 1 706  ? 88.769  110.083 128.879 1.00 84.83  ? 706  THR A CA  1 
ATOM 5483 C C   . THR A 1 706  ? 90.213  109.634 129.087 1.00 84.38  ? 706  THR A C   1 
ATOM 5484 O O   . THR A 1 706  ? 90.678  109.531 130.215 1.00 93.22  ? 706  THR A O   1 
ATOM 5485 C CB  . THR A 1 706  ? 87.914  108.836 128.635 1.00 84.65  ? 706  THR A CB  1 
ATOM 5486 O OG1 . THR A 1 706  ? 88.549  108.122 127.579 1.00 83.91  ? 706  THR A OG1 1 
ATOM 5487 C CG2 . THR A 1 706  ? 86.481  109.148 128.268 1.00 91.37  ? 706  THR A CG2 1 
ATOM 5488 N N   . SER A 1 707  ? 90.918  109.385 127.984 1.00 85.97  ? 707  SER A N   1 
ATOM 5489 C CA  . SER A 1 707  ? 92.042  108.465 127.988 1.00 92.16  ? 707  SER A CA  1 
ATOM 5490 C C   . SER A 1 707  ? 93.372  109.148 128.300 1.00 76.04  ? 707  SER A C   1 
ATOM 5491 O O   . SER A 1 707  ? 94.198  108.555 128.984 1.00 71.09  ? 707  SER A O   1 
ATOM 5492 C CB  . SER A 1 707  ? 92.112  107.718 126.674 1.00 111.11 ? 707  SER A CB  1 
ATOM 5493 O OG  . SER A 1 707  ? 91.515  108.470 125.628 1.00 119.08 ? 707  SER A OG  1 
ATOM 5494 N N   . ALA A 1 708  ? 93.605  110.349 127.763 1.00 70.25  ? 708  ALA A N   1 
ATOM 5495 C CA  . ALA A 1 708  ? 94.943  110.927 127.761 1.00 76.09  ? 708  ALA A CA  1 
ATOM 5496 C C   . ALA A 1 708  ? 95.376  111.318 129.170 1.00 83.60  ? 708  ALA A C   1 
ATOM 5497 O O   . ALA A 1 708  ? 94.545  111.736 129.974 1.00 102.56 ? 708  ALA A O   1 
ATOM 5498 C CB  . ALA A 1 708  ? 94.978  112.128 126.854 1.00 78.30  ? 708  ALA A CB  1 
ATOM 5499 N N   . TYR A 1 709  ? 96.679  111.203 129.457 1.00 80.79  ? 709  TYR A N   1 
ATOM 5500 C CA  . TYR A 1 709  ? 97.209  111.646 130.737 1.00 87.39  ? 709  TYR A CA  1 
ATOM 5501 C C   . TYR A 1 709  ? 98.503  112.422 130.528 1.00 88.67  ? 709  TYR A C   1 
ATOM 5502 O O   . TYR A 1 709  ? 99.577  111.974 130.924 1.00 98.61  ? 709  TYR A O   1 
ATOM 5503 C CB  . TYR A 1 709  ? 97.403  110.473 131.703 1.00 94.81  ? 709  TYR A CB  1 
ATOM 5504 C CG  . TYR A 1 709  ? 96.118  109.926 132.267 1.00 101.79 ? 709  TYR A CG  1 
ATOM 5505 C CD1 . TYR A 1 709  ? 95.278  109.146 131.491 1.00 104.74 ? 709  TYR A CD1 1 
ATOM 5506 C CD2 . TYR A 1 709  ? 95.723  110.210 133.563 1.00 107.74 ? 709  TYR A CD2 1 
ATOM 5507 C CE1 . TYR A 1 709  ? 94.087  108.643 131.988 1.00 105.44 ? 709  TYR A CE1 1 
ATOM 5508 C CE2 . TYR A 1 709  ? 94.534  109.718 134.077 1.00 118.22 ? 709  TYR A CE2 1 
ATOM 5509 C CZ  . TYR A 1 709  ? 93.710  108.933 133.286 1.00 114.35 ? 709  TYR A CZ  1 
ATOM 5510 O OH  . TYR A 1 709  ? 92.530  108.436 133.788 1.00 117.52 ? 709  TYR A OH  1 
ATOM 5511 N N   . PHE A 1 710  ? 98.379  113.606 129.924 1.00 83.55  ? 710  PHE A N   1 
ATOM 5512 C CA  . PHE A 1 710  ? 99.505  114.516 129.813 1.00 83.67  ? 710  PHE A CA  1 
ATOM 5513 C C   . PHE A 1 710  ? 99.815  115.054 131.204 1.00 79.01  ? 710  PHE A C   1 
ATOM 5514 O O   . PHE A 1 710  ? 98.905  115.388 131.954 1.00 69.39  ? 710  PHE A O   1 
ATOM 5515 C CB  . PHE A 1 710  ? 99.200  115.635 128.816 1.00 92.56  ? 710  PHE A CB  1 
ATOM 5516 C CG  . PHE A 1 710  ? 98.711  115.149 127.476 1.00 105.47 ? 710  PHE A CG  1 
ATOM 5517 C CD1 . PHE A 1 710  ? 99.584  114.578 126.572 1.00 114.48 ? 710  PHE A CD1 1 
ATOM 5518 C CD2 . PHE A 1 710  ? 97.367  115.224 127.131 1.00 119.60 ? 710  PHE A CD2 1 
ATOM 5519 C CE1 . PHE A 1 710  ? 99.133  114.123 125.348 1.00 128.82 ? 710  PHE A CE1 1 
ATOM 5520 C CE2 . PHE A 1 710  ? 96.918  114.768 125.898 1.00 130.61 ? 710  PHE A CE2 1 
ATOM 5521 C CZ  . PHE A 1 710  ? 97.805  114.211 125.012 1.00 134.72 ? 710  PHE A CZ  1 
ATOM 5522 N N   . GLU A 1 711  ? 101.106 115.103 131.540 1.00 90.51  ? 711  GLU A N   1 
ATOM 5523 C CA  . GLU A 1 711  ? 101.550 115.506 132.863 1.00 108.21 ? 711  GLU A CA  1 
ATOM 5524 C C   . GLU A 1 711  ? 101.182 116.960 133.131 1.00 110.49 ? 711  GLU A C   1 
ATOM 5525 O O   . GLU A 1 711  ? 100.687 117.285 134.204 1.00 111.00 ? 711  GLU A O   1 
ATOM 5526 C CB  . GLU A 1 711  ? 103.065 115.356 132.983 1.00 127.99 ? 711  GLU A CB  1 
ATOM 5527 C CG  . GLU A 1 711  ? 103.614 115.756 134.340 1.00 152.27 ? 711  GLU A CG  1 
ATOM 5528 C CD  . GLU A 1 711  ? 105.127 115.652 134.454 1.00 175.53 ? 711  GLU A CD  1 
ATOM 5529 O OE1 . GLU A 1 711  ? 105.605 114.851 135.284 1.00 188.98 ? 711  GLU A OE1 1 
ATOM 5530 O OE2 . GLU A 1 711  ? 105.828 116.375 133.714 1.00 184.59 ? 711  GLU A OE2 1 
ATOM 5531 N N   . SER A 1 712  ? 101.478 117.830 132.163 1.00 119.80 ? 712  SER A N   1 
ATOM 5532 C CA  . SER A 1 712  ? 101.365 119.268 132.346 1.00 123.40 ? 712  SER A CA  1 
ATOM 5533 C C   . SER A 1 712  ? 100.767 119.893 131.089 1.00 118.00 ? 712  SER A C   1 
ATOM 5534 O O   . SER A 1 712  ? 100.919 119.355 129.998 1.00 126.06 ? 712  SER A O   1 
ATOM 5535 C CB  . SER A 1 712  ? 102.711 119.863 132.664 1.00 121.89 ? 712  SER A CB  1 
ATOM 5536 O OG  . SER A 1 712  ? 103.366 119.120 133.680 1.00 122.59 ? 712  SER A OG  1 
ATOM 5537 N N   . LEU A 1 713  ? 100.093 121.034 131.224 1.00 98.63  ? 713  LEU A N   1 
ATOM 5538 C CA  . LEU A 1 713  ? 99.495  121.636 130.047 1.00 84.56  ? 713  LEU A CA  1 
ATOM 5539 C C   . LEU A 1 713  ? 100.577 121.905 129.009 1.00 78.11  ? 713  LEU A C   1 
ATOM 5540 O O   . LEU A 1 713  ? 100.360 121.605 127.839 1.00 94.02  ? 713  LEU A O   1 
ATOM 5541 C CB  . LEU A 1 713  ? 98.734  122.913 130.394 1.00 86.75  ? 713  LEU A CB  1 
ATOM 5542 C CG  . LEU A 1 713  ? 97.233  122.777 130.656 1.00 93.86  ? 713  LEU A CG  1 
ATOM 5543 C CD1 . LEU A 1 713  ? 96.512  124.021 130.162 1.00 108.01 ? 713  LEU A CD1 1 
ATOM 5544 C CD2 . LEU A 1 713  ? 96.629  121.538 130.009 1.00 89.33  ? 713  LEU A CD2 1 
ATOM 5545 N N   . VAL A 1 714  ? 101.752 122.390 129.428 1.00 75.47  ? 714  VAL A N   1 
ATOM 5546 C CA  . VAL A 1 714  ? 102.820 122.633 128.469 1.00 89.35  ? 714  VAL A CA  1 
ATOM 5547 C C   . VAL A 1 714  ? 102.945 121.436 127.535 1.00 96.42  ? 714  VAL A C   1 
ATOM 5548 O O   . VAL A 1 714  ? 103.067 121.620 126.326 1.00 108.85 ? 714  VAL A O   1 
ATOM 5549 C CB  . VAL A 1 714  ? 104.192 122.937 129.099 1.00 104.06 ? 714  VAL A CB  1 
ATOM 5550 C CG1 . VAL A 1 714  ? 104.240 124.341 129.671 1.00 119.67 ? 714  VAL A CG1 1 
ATOM 5551 C CG2 . VAL A 1 714  ? 104.616 121.900 130.130 1.00 110.44 ? 714  VAL A CG2 1 
ATOM 5552 N N   . GLU A 1 715  ? 102.904 120.223 128.096 1.00 95.87  ? 715  GLU A N   1 
ATOM 5553 C CA  . GLU A 1 715  ? 103.000 119.013 127.300 1.00 99.84  ? 715  GLU A CA  1 
ATOM 5554 C C   . GLU A 1 715  ? 101.797 118.901 126.368 1.00 80.27  ? 715  GLU A C   1 
ATOM 5555 O O   . GLU A 1 715  ? 101.989 118.713 125.175 1.00 79.49  ? 715  GLU A O   1 
ATOM 5556 C CB  . GLU A 1 715  ? 103.122 117.776 128.190 1.00 129.64 ? 715  GLU A CB  1 
ATOM 5557 C CG  . GLU A 1 715  ? 102.660 116.490 127.522 1.00 152.75 ? 715  GLU A CG  1 
ATOM 5558 C CD  . GLU A 1 715  ? 102.750 115.253 128.399 1.00 168.71 ? 715  GLU A CD  1 
ATOM 5559 O OE1 . GLU A 1 715  ? 102.173 114.226 128.016 1.00 167.79 ? 715  GLU A OE1 1 
ATOM 5560 O OE2 . GLU A 1 715  ? 103.413 115.309 129.453 1.00 175.19 ? 715  GLU A OE2 1 
ATOM 5561 N N   . LEU A 1 716  ? 100.571 119.005 126.899 1.00 67.59  ? 716  LEU A N   1 
ATOM 5562 C CA  . LEU A 1 716  ? 99.403  118.734 126.078 1.00 61.38  ? 716  LEU A CA  1 
ATOM 5563 C C   . LEU A 1 716  ? 99.521  119.513 124.779 1.00 62.85  ? 716  LEU A C   1 
ATOM 5564 O O   . LEU A 1 716  ? 99.244  118.972 123.718 1.00 75.32  ? 716  LEU A O   1 
ATOM 5565 C CB  . LEU A 1 716  ? 98.104  119.125 126.775 1.00 66.20  ? 716  LEU A CB  1 
ATOM 5566 C CG  . LEU A 1 716  ? 96.880  119.112 125.851 1.00 75.36  ? 716  LEU A CG  1 
ATOM 5567 C CD1 . LEU A 1 716  ? 95.797  118.160 126.348 1.00 80.21  ? 716  LEU A CD1 1 
ATOM 5568 C CD2 . LEU A 1 716  ? 96.322  120.519 125.655 1.00 82.78  ? 716  LEU A CD2 1 
ATOM 5569 N N   . VAL A 1 717  ? 99.921  120.782 124.868 1.00 68.26  ? 717  VAL A N   1 
ATOM 5570 C CA  . VAL A 1 717  ? 100.135 121.574 123.671 1.00 78.79  ? 717  VAL A CA  1 
ATOM 5571 C C   . VAL A 1 717  ? 101.272 120.970 122.854 1.00 78.89  ? 717  VAL A C   1 
ATOM 5572 O O   . VAL A 1 717  ? 101.118 120.823 121.647 1.00 96.32  ? 717  VAL A O   1 
ATOM 5573 C CB  . VAL A 1 717  ? 100.381 123.063 123.975 1.00 90.65  ? 717  VAL A CB  1 
ATOM 5574 C CG1 . VAL A 1 717  ? 101.408 123.698 123.041 1.00 93.00  ? 717  VAL A CG1 1 
ATOM 5575 C CG2 . VAL A 1 717  ? 99.072  123.843 123.940 1.00 98.26  ? 717  VAL A CG2 1 
ATOM 5576 N N   . SER A 1 718  ? 102.392 120.614 123.493 1.00 66.09  ? 718  SER A N   1 
ATOM 5577 C CA  . SER A 1 718  ? 103.560 120.182 122.738 1.00 66.04  ? 718  SER A CA  1 
ATOM 5578 C C   . SER A 1 718  ? 103.282 118.878 121.992 1.00 63.01  ? 718  SER A C   1 
ATOM 5579 O O   . SER A 1 718  ? 103.549 118.783 120.798 1.00 64.92  ? 718  SER A O   1 
ATOM 5580 C CB  . SER A 1 718  ? 104.775 120.050 123.604 1.00 72.91  ? 718  SER A CB  1 
ATOM 5581 O OG  . SER A 1 718  ? 105.877 119.574 122.843 1.00 76.04  ? 718  SER A OG  1 
ATOM 5582 N N   . TYR A 1 719  ? 102.770 117.865 122.696 1.00 64.28  ? 719  TYR A N   1 
ATOM 5583 C CA  . TYR A 1 719  ? 102.471 116.595 122.058 1.00 67.40  ? 719  TYR A CA  1 
ATOM 5584 C C   . TYR A 1 719  ? 101.612 116.824 120.831 1.00 61.52  ? 719  TYR A C   1 
ATOM 5585 O O   . TYR A 1 719  ? 101.924 116.307 119.772 1.00 77.23  ? 719  TYR A O   1 
ATOM 5586 C CB  . TYR A 1 719  ? 101.696 115.620 122.946 1.00 73.27  ? 719  TYR A CB  1 
ATOM 5587 C CG  . TYR A 1 719  ? 101.262 114.361 122.235 1.00 71.55  ? 719  TYR A CG  1 
ATOM 5588 C CD1 . TYR A 1 719  ? 102.186 113.445 121.765 1.00 73.45  ? 719  TYR A CD1 1 
ATOM 5589 C CD2 . TYR A 1 719  ? 99.926  114.089 122.014 1.00 70.25  ? 719  TYR A CD2 1 
ATOM 5590 C CE1 . TYR A 1 719  ? 101.791 112.291 121.104 1.00 76.53  ? 719  TYR A CE1 1 
ATOM 5591 C CE2 . TYR A 1 719  ? 99.512  112.938 121.365 1.00 72.89  ? 719  TYR A CE2 1 
ATOM 5592 C CZ  . TYR A 1 719  ? 100.447 112.029 120.908 1.00 72.50  ? 719  TYR A CZ  1 
ATOM 5593 O OH  . TYR A 1 719  ? 100.045 110.889 120.244 1.00 71.77  ? 719  TYR A OH  1 
ATOM 5594 N N   . TYR A 1 720  ? 100.522 117.565 120.966 1.00 55.20  ? 720  TYR A N   1 
ATOM 5595 C CA  . TYR A 1 720  ? 99.622  117.650 119.837 1.00 69.28  ? 720  TYR A CA  1 
ATOM 5596 C C   . TYR A 1 720  ? 100.261 118.434 118.686 1.00 84.34  ? 720  TYR A C   1 
ATOM 5597 O O   . TYR A 1 720  ? 99.882  118.191 117.548 1.00 95.51  ? 720  TYR A O   1 
ATOM 5598 C CB  . TYR A 1 720  ? 98.233  118.135 120.256 1.00 71.95  ? 720  TYR A CB  1 
ATOM 5599 C CG  . TYR A 1 720  ? 97.431  117.076 120.959 1.00 71.95  ? 720  TYR A CG  1 
ATOM 5600 C CD1 . TYR A 1 720  ? 97.203  115.851 120.369 1.00 75.78  ? 720  TYR A CD1 1 
ATOM 5601 C CD2 . TYR A 1 720  ? 96.942  117.283 122.234 1.00 93.32  ? 720  TYR A CD2 1 
ATOM 5602 C CE1 . TYR A 1 720  ? 96.480  114.862 121.017 1.00 92.05  ? 720  TYR A CE1 1 
ATOM 5603 C CE2 . TYR A 1 720  ? 96.225  116.307 122.903 1.00 106.66 ? 720  TYR A CE2 1 
ATOM 5604 C CZ  . TYR A 1 720  ? 95.990  115.086 122.293 1.00 103.28 ? 720  TYR A CZ  1 
ATOM 5605 O OH  . TYR A 1 720  ? 95.283  114.103 122.945 1.00 100.67 ? 720  TYR A OH  1 
ATOM 5606 N N   . GLU A 1 721  ? 101.270 119.289 118.913 1.00 81.94  ? 721  GLU A N   1 
ATOM 5607 C CA  . GLU A 1 721  ? 101.906 119.943 117.775 1.00 89.18  ? 721  GLU A CA  1 
ATOM 5608 C C   . GLU A 1 721  ? 102.571 118.905 116.872 1.00 95.74  ? 721  GLU A C   1 
ATOM 5609 O O   . GLU A 1 721  ? 102.471 118.998 115.654 1.00 106.22 ? 721  GLU A O   1 
ATOM 5610 C CB  . GLU A 1 721  ? 102.931 120.993 118.195 1.00 104.68 ? 721  GLU A CB  1 
ATOM 5611 C CG  . GLU A 1 721  ? 102.315 122.187 118.901 1.00 129.85 ? 721  GLU A CG  1 
ATOM 5612 C CD  . GLU A 1 721  ? 103.295 123.291 119.267 1.00 152.53 ? 721  GLU A CD  1 
ATOM 5613 O OE1 . GLU A 1 721  ? 103.465 123.552 120.479 1.00 163.91 ? 721  GLU A OE1 1 
ATOM 5614 O OE2 . GLU A 1 721  ? 103.882 123.894 118.340 1.00 157.20 ? 721  GLU A OE2 1 
ATOM 5615 N N   . LYS A 1 722  ? 103.234 117.907 117.469 1.00 101.92 ? 722  LYS A N   1 
ATOM 5616 C CA  . LYS A 1 722  ? 103.895 116.855 116.710 1.00 104.84 ? 722  LYS A CA  1 
ATOM 5617 C C   . LYS A 1 722  ? 102.879 115.901 116.075 1.00 91.07  ? 722  LYS A C   1 
ATOM 5618 O O   . LYS A 1 722  ? 103.112 115.451 114.958 1.00 100.06 ? 722  LYS A O   1 
ATOM 5619 C CB  . LYS A 1 722  ? 104.874 116.090 117.605 1.00 126.84 ? 722  LYS A CB  1 
ATOM 5620 C CG  . LYS A 1 722  ? 106.054 116.915 118.105 1.00 153.30 ? 722  LYS A CG  1 
ATOM 5621 C CD  . LYS A 1 722  ? 106.939 116.182 119.097 1.00 187.97 ? 722  LYS A CD  1 
ATOM 5622 C CE  . LYS A 1 722  ? 107.584 114.934 118.529 1.00 207.72 ? 722  LYS A CE  1 
ATOM 5623 N NZ  . LYS A 1 722  ? 108.465 114.271 119.521 1.00 213.33 ? 722  LYS A NZ  1 
ATOM 5624 N N   . HIS A 1 723  ? 101.774 115.585 116.772 1.00 71.44  ? 723  HIS A N   1 
ATOM 5625 C CA  . HIS A 1 723  ? 100.798 114.609 116.297 1.00 66.38  ? 723  HIS A CA  1 
ATOM 5626 C C   . HIS A 1 723  ? 99.543  115.334 115.823 1.00 58.46  ? 723  HIS A C   1 
ATOM 5627 O O   . HIS A 1 723  ? 99.650  116.458 115.351 1.00 62.29  ? 723  HIS A O   1 
ATOM 5628 C CB  . HIS A 1 723  ? 100.559 113.534 117.359 1.00 75.81  ? 723  HIS A CB  1 
ATOM 5629 C CG  . HIS A 1 723  ? 101.802 112.791 117.714 1.00 97.79  ? 723  HIS A CG  1 
ATOM 5630 N ND1 . HIS A 1 723  ? 102.909 113.424 118.242 1.00 105.40 ? 723  HIS A ND1 1 
ATOM 5631 C CD2 . HIS A 1 723  ? 102.130 111.493 117.614 1.00 120.46 ? 723  HIS A CD2 1 
ATOM 5632 C CE1 . HIS A 1 723  ? 103.866 112.535 118.460 1.00 122.02 ? 723  HIS A CE1 1 
ATOM 5633 N NE2 . HIS A 1 723  ? 103.415 111.355 118.085 1.00 132.33 ? 723  HIS A NE2 1 
ATOM 5634 N N   . SER A 1 724  ? 98.363  114.705 115.903 1.00 57.82  ? 724  SER A N   1 
ATOM 5635 C CA  . SER A 1 724  ? 97.180  115.304 115.302 1.00 64.03  ? 724  SER A CA  1 
ATOM 5636 C C   . SER A 1 724  ? 95.949  115.123 116.180 1.00 63.53  ? 724  SER A C   1 
ATOM 5637 O O   . SER A 1 724  ? 95.531  113.999 116.433 1.00 69.39  ? 724  SER A O   1 
ATOM 5638 C CB  . SER A 1 724  ? 96.929  114.734 113.937 1.00 74.78  ? 724  SER A CB  1 
ATOM 5639 O OG  . SER A 1 724  ? 96.668  113.342 114.020 1.00 81.92  ? 724  SER A OG  1 
ATOM 5640 N N   . LEU A 1 725  ? 95.338  116.244 116.578 1.00 67.49  ? 725  LEU A N   1 
ATOM 5641 C CA  . LEU A 1 725  ? 94.246  116.237 117.536 1.00 73.10  ? 725  LEU A CA  1 
ATOM 5642 C C   . LEU A 1 725  ? 92.904  116.024 116.838 1.00 63.82  ? 725  LEU A C   1 
ATOM 5643 O O   . LEU A 1 725  ? 92.104  115.208 117.288 1.00 67.92  ? 725  LEU A O   1 
ATOM 5644 C CB  . LEU A 1 725  ? 94.271  117.546 118.327 1.00 84.57  ? 725  LEU A CB  1 
ATOM 5645 C CG  . LEU A 1 725  ? 93.193  117.689 119.401 1.00 103.79 ? 725  LEU A CG  1 
ATOM 5646 C CD1 . LEU A 1 725  ? 93.294  116.590 120.456 1.00 108.18 ? 725  LEU A CD1 1 
ATOM 5647 C CD2 . LEU A 1 725  ? 93.289  119.060 120.059 1.00 113.15 ? 725  LEU A CD2 1 
ATOM 5648 N N   . TYR A 1 726  ? 92.644  116.767 115.762 1.00 62.68  ? 726  TYR A N   1 
ATOM 5649 C CA  . TYR A 1 726  ? 91.393  116.641 115.027 1.00 69.87  ? 726  TYR A CA  1 
ATOM 5650 C C   . TYR A 1 726  ? 91.690  116.338 113.565 1.00 78.44  ? 726  TYR A C   1 
ATOM 5651 O O   . TYR A 1 726  ? 92.576  116.950 112.969 1.00 81.72  ? 726  TYR A O   1 
ATOM 5652 C CB  . TYR A 1 726  ? 90.569  117.929 115.090 1.00 73.45  ? 726  TYR A CB  1 
ATOM 5653 C CG  . TYR A 1 726  ? 89.161  117.855 114.547 1.00 78.58  ? 726  TYR A CG  1 
ATOM 5654 C CD1 . TYR A 1 726  ? 88.470  116.659 114.432 1.00 88.88  ? 726  TYR A CD1 1 
ATOM 5655 C CD2 . TYR A 1 726  ? 88.504  119.006 114.150 1.00 90.05  ? 726  TYR A CD2 1 
ATOM 5656 C CE1 . TYR A 1 726  ? 87.170  116.611 113.955 1.00 98.24  ? 726  TYR A CE1 1 
ATOM 5657 C CE2 . TYR A 1 726  ? 87.206  118.976 113.666 1.00 102.45 ? 726  TYR A CE2 1 
ATOM 5658 C CZ  . TYR A 1 726  ? 86.533  117.772 113.566 1.00 100.33 ? 726  TYR A CZ  1 
ATOM 5659 O OH  . TYR A 1 726  ? 85.244  117.725 113.092 1.00 99.15  ? 726  TYR A OH  1 
ATOM 5660 N N   . ARG A 1 727  ? 90.949  115.386 112.990 1.00 85.09  ? 727  ARG A N   1 
ATOM 5661 C CA  . ARG A 1 727  ? 91.219  114.994 111.622 1.00 87.62  ? 727  ARG A CA  1 
ATOM 5662 C C   . ARG A 1 727  ? 92.732  114.811 111.537 1.00 91.30  ? 727  ARG A C   1 
ATOM 5663 O O   . ARG A 1 727  ? 93.297  114.074 112.345 1.00 110.12 ? 727  ARG A O   1 
ATOM 5664 C CB  . ARG A 1 727  ? 90.646  116.056 110.685 1.00 93.00  ? 727  ARG A CB  1 
ATOM 5665 C CG  . ARG A 1 727  ? 89.205  116.426 111.002 1.00 94.37  ? 727  ARG A CG  1 
ATOM 5666 C CD  . ARG A 1 727  ? 88.230  115.404 110.454 1.00 92.76  ? 727  ARG A CD  1 
ATOM 5667 N NE  . ARG A 1 727  ? 86.886  115.619 110.973 1.00 99.43  ? 727  ARG A NE  1 
ATOM 5668 C CZ  . ARG A 1 727  ? 85.876  116.162 110.298 1.00 110.55 ? 727  ARG A CZ  1 
ATOM 5669 N NH1 . ARG A 1 727  ? 86.032  116.549 109.044 1.00 116.51 ? 727  ARG A NH1 1 
ATOM 5670 N NH2 . ARG A 1 727  ? 84.705  116.320 110.890 1.00 113.05 ? 727  ARG A NH2 1 
ATOM 5671 N N   . LYS A 1 728  ? 93.405  115.512 110.624 1.00 83.60  ? 728  LYS A N   1 
ATOM 5672 C CA  . LYS A 1 728  ? 94.841  115.360 110.540 1.00 95.95  ? 728  LYS A CA  1 
ATOM 5673 C C   . LYS A 1 728  ? 95.527  116.701 110.753 1.00 91.19  ? 728  LYS A C   1 
ATOM 5674 O O   . LYS A 1 728  ? 96.612  116.904 110.223 1.00 101.16 ? 728  LYS A O   1 
ATOM 5675 C CB  . LYS A 1 728  ? 95.231  114.762 109.182 1.00 129.17 ? 728  LYS A CB  1 
ATOM 5676 C CG  . LYS A 1 728  ? 94.814  113.313 108.950 1.00 159.01 ? 728  LYS A CG  1 
ATOM 5677 C CD  . LYS A 1 728  ? 93.320  113.110 108.766 1.00 182.24 ? 728  LYS A CD  1 
ATOM 5678 C CE  . LYS A 1 728  ? 92.946  111.690 108.393 1.00 200.63 ? 728  LYS A CE  1 
ATOM 5679 N NZ  . LYS A 1 728  ? 93.489  111.297 107.070 1.00 209.36 ? 728  LYS A NZ  1 
ATOM 5680 N N   . MET A 1 729  ? 94.925  117.619 111.513 1.00 90.05  ? 729  MET A N   1 
ATOM 5681 C CA  . MET A 1 729  ? 95.550  118.927 111.649 1.00 95.46  ? 729  MET A CA  1 
ATOM 5682 C C   . MET A 1 729  ? 96.096  119.071 113.065 1.00 67.19  ? 729  MET A C   1 
ATOM 5683 O O   . MET A 1 729  ? 95.360  118.937 114.030 1.00 64.96  ? 729  MET A O   1 
ATOM 5684 C CB  . MET A 1 729  ? 94.571  120.050 111.280 1.00 117.22 ? 729  MET A CB  1 
ATOM 5685 C CG  . MET A 1 729  ? 94.849  121.407 111.937 1.00 130.67 ? 729  MET A CG  1 
ATOM 5686 S SD  . MET A 1 729  ? 94.335  121.549 113.680 1.00 138.21 ? 729  MET A SD  1 
ATOM 5687 C CE  . MET A 1 729  ? 92.908  120.464 113.727 1.00 144.83 ? 729  MET A CE  1 
ATOM 5688 N N   . ARG A 1 730  ? 97.413  119.253 113.169 1.00 58.97  ? 730  ARG A N   1 
ATOM 5689 C CA  . ARG A 1 730  ? 98.051  119.504 114.445 1.00 65.34  ? 730  ARG A CA  1 
ATOM 5690 C C   . ARG A 1 730  ? 97.694  120.914 114.878 1.00 64.51  ? 730  ARG A C   1 
ATOM 5691 O O   . ARG A 1 730  ? 97.554  121.793 114.039 1.00 60.31  ? 730  ARG A O   1 
ATOM 5692 C CB  . ARG A 1 730  ? 99.572  119.312 114.375 1.00 82.15  ? 730  ARG A CB  1 
ATOM 5693 C CG  . ARG A 1 730  ? 100.318 120.190 113.377 1.00 101.92 ? 730  ARG A CG  1 
ATOM 5694 C CD  . ARG A 1 730  ? 100.075 119.845 111.921 1.00 118.39 ? 730  ARG A CD  1 
ATOM 5695 N NE  . ARG A 1 730  ? 100.220 118.422 111.640 1.00 125.06 ? 730  ARG A NE  1 
ATOM 5696 C CZ  . ARG A 1 730  ? 101.363 117.750 111.709 1.00 133.59 ? 730  ARG A CZ  1 
ATOM 5697 N NH1 . ARG A 1 730  ? 102.481 118.379 112.027 1.00 130.02 ? 730  ARG A NH1 1 
ATOM 5698 N NH2 . ARG A 1 730  ? 101.382 116.455 111.438 1.00 138.13 ? 730  ARG A NH2 1 
ATOM 5699 N N   . LEU A 1 731  ? 97.537  121.125 116.191 1.00 74.39  ? 731  LEU A N   1 
ATOM 5700 C CA  . LEU A 1 731  ? 97.594  122.480 116.706 1.00 76.00  ? 731  LEU A CA  1 
ATOM 5701 C C   . LEU A 1 731  ? 98.936  123.010 116.234 1.00 79.23  ? 731  LEU A C   1 
ATOM 5702 O O   . LEU A 1 731  ? 99.935  122.318 116.389 1.00 80.40  ? 731  LEU A O   1 
ATOM 5703 C CB  . LEU A 1 731  ? 97.483  122.486 118.232 1.00 73.53  ? 731  LEU A CB  1 
ATOM 5704 C CG  . LEU A 1 731  ? 96.261  121.769 118.809 1.00 82.82  ? 731  LEU A CG  1 
ATOM 5705 C CD1 . LEU A 1 731  ? 96.083  122.116 120.276 1.00 91.03  ? 731  LEU A CD1 1 
ATOM 5706 C CD2 . LEU A 1 731  ? 94.982  122.080 118.033 1.00 80.02  ? 731  LEU A CD2 1 
ATOM 5707 N N   . ARG A 1 732  ? 98.933  124.144 115.537 1.00 87.24  ? 732  ARG A N   1 
ATOM 5708 C CA  . ARG A 1 732  ? 100.152 124.611 114.904 1.00 99.44  ? 732  ARG A CA  1 
ATOM 5709 C C   . ARG A 1 732  ? 100.387 126.083 115.211 1.00 99.38  ? 732  ARG A C   1 
ATOM 5710 O O   . ARG A 1 732  ? 101.537 126.513 115.234 1.00 98.29  ? 732  ARG A O   1 
ATOM 5711 C CB  . ARG A 1 732  ? 100.091 124.394 113.391 1.00 117.19 ? 732  ARG A CB  1 
ATOM 5712 C CG  . ARG A 1 732  ? 98.934  125.117 112.715 1.00 128.80 ? 732  ARG A CG  1 
ATOM 5713 C CD  . ARG A 1 732  ? 98.863  125.127 111.192 1.00 143.89 ? 732  ARG A CD  1 
ATOM 5714 N NE  . ARG A 1 732  ? 98.452  123.887 110.539 1.00 152.29 ? 732  ARG A NE  1 
ATOM 5715 C CZ  . ARG A 1 732  ? 99.243  122.838 110.330 1.00 161.35 ? 732  ARG A CZ  1 
ATOM 5716 N NH1 . ARG A 1 732  ? 98.781  121.783 109.680 1.00 163.82 ? 732  ARG A NH1 1 
ATOM 5717 N NH2 . ARG A 1 732  ? 100.497 122.864 110.749 1.00 159.73 ? 732  ARG A NH2 1 
ATOM 5718 N N   . TYR A 1 733  ? 99.306  126.852 115.397 1.00 102.13 ? 733  TYR A N   1 
ATOM 5719 C CA  . TYR A 1 733  ? 99.456  128.275 115.656 1.00 108.84 ? 733  TYR A CA  1 
ATOM 5720 C C   . TYR A 1 733  ? 98.900  128.701 117.018 1.00 98.78  ? 733  TYR A C   1 
ATOM 5721 O O   . TYR A 1 733  ? 97.742  128.454 117.353 1.00 83.61  ? 733  TYR A O   1 
ATOM 5722 C CB  . TYR A 1 733  ? 98.813  129.083 114.535 1.00 123.91 ? 733  TYR A CB  1 
ATOM 5723 C CG  . TYR A 1 733  ? 99.492  128.927 113.197 1.00 145.26 ? 733  TYR A CG  1 
ATOM 5724 C CD1 . TYR A 1 733  ? 100.841 129.217 113.033 1.00 146.19 ? 733  TYR A CD1 1 
ATOM 5725 C CD2 . TYR A 1 733  ? 98.784  128.501 112.084 1.00 158.90 ? 733  TYR A CD2 1 
ATOM 5726 C CE1 . TYR A 1 733  ? 101.470 129.079 111.806 1.00 149.67 ? 733  TYR A CE1 1 
ATOM 5727 C CE2 . TYR A 1 733  ? 99.394  128.365 110.846 1.00 162.40 ? 733  TYR A CE2 1 
ATOM 5728 C CZ  . TYR A 1 733  ? 100.742 128.655 110.707 1.00 162.52 ? 733  TYR A CZ  1 
ATOM 5729 O OH  . TYR A 1 733  ? 101.366 128.517 109.491 1.00 174.25 ? 733  TYR A OH  1 
ATOM 5730 N N   . PRO A 1 734  ? 99.715  129.436 117.813 1.00 93.98  ? 734  PRO A N   1 
ATOM 5731 C CA  . PRO A 1 734  ? 99.295  129.963 119.111 1.00 90.99  ? 734  PRO A CA  1 
ATOM 5732 C C   . PRO A 1 734  ? 98.641  131.342 119.026 1.00 83.77  ? 734  PRO A C   1 
ATOM 5733 O O   . PRO A 1 734  ? 99.263  132.303 118.577 1.00 83.78  ? 734  PRO A O   1 
ATOM 5734 C CB  . PRO A 1 734  ? 100.639 130.028 119.854 1.00 92.09  ? 734  PRO A CB  1 
ATOM 5735 C CG  . PRO A 1 734  ? 101.648 130.397 118.785 1.00 89.92  ? 734  PRO A CG  1 
ATOM 5736 C CD  . PRO A 1 734  ? 101.109 129.797 117.503 1.00 90.91  ? 734  PRO A CD  1 
ATOM 5737 N N   . VAL A 1 735  ? 97.399  131.439 119.511 1.00 72.94  ? 735  VAL A N   1 
ATOM 5738 C CA  . VAL A 1 735  ? 96.585  132.630 119.331 1.00 67.60  ? 735  VAL A CA  1 
ATOM 5739 C C   . VAL A 1 735  ? 96.982  133.643 120.396 1.00 67.51  ? 735  VAL A C   1 
ATOM 5740 O O   . VAL A 1 735  ? 96.189  133.989 121.264 1.00 67.26  ? 735  VAL A O   1 
ATOM 5741 C CB  . VAL A 1 735  ? 95.081  132.305 119.412 1.00 71.92  ? 735  VAL A CB  1 
ATOM 5742 C CG1 . VAL A 1 735  ? 94.227  133.412 118.815 1.00 79.53  ? 735  VAL A CG1 1 
ATOM 5743 C CG2 . VAL A 1 735  ? 94.747  130.987 118.745 1.00 73.15  ? 735  VAL A CG2 1 
ATOM 5744 N N   . THR A 1 736  ? 98.229  134.103 120.327 1.00 78.41  ? 736  THR A N   1 
ATOM 5745 C CA  . THR A 1 736  ? 98.757  135.018 121.324 1.00 97.85  ? 736  THR A CA  1 
ATOM 5746 C C   . THR A 1 736  ? 98.078  136.376 121.177 1.00 114.98 ? 736  THR A C   1 
ATOM 5747 O O   . THR A 1 736  ? 97.685  136.744 120.075 1.00 124.25 ? 736  THR A O   1 
ATOM 5748 C CB  . THR A 1 736  ? 100.283 135.175 121.236 1.00 108.95 ? 736  THR A CB  1 
ATOM 5749 O OG1 . THR A 1 736  ? 100.546 136.576 121.151 1.00 119.21 ? 736  THR A OG1 1 
ATOM 5750 C CG2 . THR A 1 736  ? 100.928 134.503 120.043 1.00 114.06 ? 736  THR A CG2 1 
ATOM 5751 N N   . PRO A 1 737  ? 97.934  137.168 122.265 1.00 133.64 ? 737  PRO A N   1 
ATOM 5752 C CA  . PRO A 1 737  ? 97.446  138.542 122.153 1.00 136.12 ? 737  PRO A CA  1 
ATOM 5753 C C   . PRO A 1 737  ? 98.304  139.352 121.185 1.00 138.61 ? 737  PRO A C   1 
ATOM 5754 O O   . PRO A 1 737  ? 97.780  140.033 120.307 1.00 141.92 ? 737  PRO A O   1 
ATOM 5755 C CB  . PRO A 1 737  ? 97.568  139.125 123.568 1.00 140.35 ? 737  PRO A CB  1 
ATOM 5756 C CG  . PRO A 1 737  ? 97.640  137.920 124.482 1.00 148.99 ? 737  PRO A CG  1 
ATOM 5757 C CD  . PRO A 1 737  ? 98.231  136.794 123.656 1.00 147.27 ? 737  PRO A CD  1 
ATOM 5758 N N   . GLU A 1 738  ? 99.627  139.225 121.336 1.00 139.08 ? 738  GLU A N   1 
ATOM 5759 C CA  . GLU A 1 738  ? 100.580 139.997 120.558 1.00 148.07 ? 738  GLU A CA  1 
ATOM 5760 C C   . GLU A 1 738  ? 100.319 139.764 119.073 1.00 137.83 ? 738  GLU A C   1 
ATOM 5761 O O   . GLU A 1 738  ? 100.234 140.716 118.300 1.00 144.07 ? 738  GLU A O   1 
ATOM 5762 C CB  . GLU A 1 738  ? 102.020 139.629 120.927 1.00 163.11 ? 738  GLU A CB  1 
ATOM 5763 C CG  . GLU A 1 738  ? 102.386 139.952 122.370 1.00 182.69 ? 738  GLU A CG  1 
ATOM 5764 C CD  . GLU A 1 738  ? 101.718 139.091 123.431 1.00 186.56 ? 738  GLU A CD  1 
ATOM 5765 O OE1 . GLU A 1 738  ? 101.942 139.350 124.630 1.00 193.44 ? 738  GLU A OE1 1 
ATOM 5766 O OE2 . GLU A 1 738  ? 100.977 138.161 123.058 1.00 177.13 ? 738  GLU A OE2 1 
ATOM 5767 N N   . LEU A 1 739  ? 100.166 138.494 118.690 1.00 127.85 ? 739  LEU A N   1 
ATOM 5768 C CA  . LEU A 1 739  ? 99.919  138.160 117.299 1.00 126.03 ? 739  LEU A CA  1 
ATOM 5769 C C   . LEU A 1 739  ? 98.564  138.714 116.862 1.00 120.01 ? 739  LEU A C   1 
ATOM 5770 O O   . LEU A 1 739  ? 98.410  139.113 115.713 1.00 136.31 ? 739  LEU A O   1 
ATOM 5771 C CB  . LEU A 1 739  ? 99.989  136.643 117.109 1.00 132.78 ? 739  LEU A CB  1 
ATOM 5772 C CG  . LEU A 1 739  ? 99.782  136.158 115.674 1.00 140.37 ? 739  LEU A CG  1 
ATOM 5773 C CD1 . LEU A 1 739  ? 101.017 136.417 114.823 1.00 146.32 ? 739  LEU A CD1 1 
ATOM 5774 C CD2 . LEU A 1 739  ? 99.420  134.686 115.636 1.00 141.56 ? 739  LEU A CD2 1 
ATOM 5775 N N   . LEU A 1 740  ? 97.582  138.752 117.769 1.00 111.76 ? 740  LEU A N   1 
ATOM 5776 C CA  . LEU A 1 740  ? 96.242  139.156 117.379 1.00 117.85 ? 740  LEU A CA  1 
ATOM 5777 C C   . LEU A 1 740  ? 96.276  140.561 116.782 1.00 136.59 ? 740  LEU A C   1 
ATOM 5778 O O   . LEU A 1 740  ? 95.575  140.827 115.810 1.00 146.29 ? 740  LEU A O   1 
ATOM 5779 C CB  . LEU A 1 740  ? 95.288  139.069 118.576 1.00 120.04 ? 740  LEU A CB  1 
ATOM 5780 C CG  . LEU A 1 740  ? 93.797  139.233 118.264 1.00 126.23 ? 740  LEU A CG  1 
ATOM 5781 C CD1 . LEU A 1 740  ? 93.394  140.700 118.140 1.00 130.25 ? 740  LEU A CD1 1 
ATOM 5782 C CD2 . LEU A 1 740  ? 93.422  138.470 117.000 1.00 125.80 ? 740  LEU A CD2 1 
ATOM 5783 N N   . GLU A 1 741  ? 97.118  141.445 117.336 1.00 148.44 ? 741  GLU A N   1 
ATOM 5784 C CA  . GLU A 1 741  ? 97.229  142.803 116.826 1.00 158.99 ? 741  GLU A CA  1 
ATOM 5785 C C   . GLU A 1 741  ? 97.699  142.775 115.373 1.00 152.31 ? 741  GLU A C   1 
ATOM 5786 O O   . GLU A 1 741  ? 97.113  143.450 114.529 1.00 153.76 ? 741  GLU A O   1 
ATOM 5787 C CB  . GLU A 1 741  ? 98.176  143.646 117.685 1.00 170.22 ? 741  GLU A CB  1 
ATOM 5788 C CG  . GLU A 1 741  ? 97.596  144.029 119.035 1.00 182.18 ? 741  GLU A CG  1 
ATOM 5789 C CD  . GLU A 1 741  ? 98.268  145.219 119.704 1.00 196.80 ? 741  GLU A CD  1 
ATOM 5790 O OE1 . GLU A 1 741  ? 98.179  146.333 119.148 1.00 195.70 ? 741  GLU A OE1 1 
ATOM 5791 O OE2 . GLU A 1 741  ? 98.879  145.028 120.775 1.00 211.66 ? 741  GLU A OE2 1 
ATOM 5792 N N   . ARG A 1 742  ? 98.743  141.982 115.097 1.00 135.71 ? 742  ARG A N   1 
ATOM 5793 C CA  . ARG A 1 742  ? 99.315  141.869 113.764 1.00 127.51 ? 742  ARG A CA  1 
ATOM 5794 C C   . ARG A 1 742  ? 98.208  141.708 112.721 1.00 132.59 ? 742  ARG A C   1 
ATOM 5795 O O   . ARG A 1 742  ? 98.043  142.576 111.868 1.00 142.79 ? 742  ARG A O   1 
ATOM 5796 C CB  . ARG A 1 742  ? 100.304 140.702 113.696 1.00 127.36 ? 742  ARG A CB  1 
ATOM 5797 C CG  . ARG A 1 742  ? 100.937 140.508 112.327 1.00 139.26 ? 742  ARG A CG  1 
ATOM 5798 C CD  . ARG A 1 742  ? 101.828 141.677 111.960 1.00 150.78 ? 742  ARG A CD  1 
ATOM 5799 N NE  . ARG A 1 742  ? 102.840 141.892 112.982 1.00 157.68 ? 742  ARG A NE  1 
ATOM 5800 C CZ  . ARG A 1 742  ? 103.808 141.027 113.259 1.00 170.96 ? 742  ARG A CZ  1 
ATOM 5801 N NH1 . ARG A 1 742  ? 103.932 139.930 112.532 1.00 177.10 ? 742  ARG A NH1 1 
ATOM 5802 N NH2 . ARG A 1 742  ? 104.657 141.267 114.244 1.00 178.79 ? 742  ARG A NH2 1 
ATOM 5803 N N   . TYR A 1 743  ? 97.459  140.599 112.792 1.00 136.84 ? 743  TYR A N   1 
ATOM 5804 C CA  . TYR A 1 743  ? 96.406  140.322 111.827 1.00 147.38 ? 743  TYR A CA  1 
ATOM 5805 C C   . TYR A 1 743  ? 95.219  141.261 112.087 1.00 151.01 ? 743  TYR A C   1 
ATOM 5806 O O   . TYR A 1 743  ? 95.150  141.847 113.189 1.00 150.51 ? 743  TYR A O   1 
ATOM 5807 C CB  . TYR A 1 743  ? 95.984  138.845 111.859 1.00 154.92 ? 743  TYR A CB  1 
ATOM 5808 C CG  . TYR A 1 743  ? 94.961  138.481 110.808 1.00 181.00 ? 743  TYR A CG  1 
ATOM 5809 C CD1 . TYR A 1 743  ? 93.686  139.031 110.830 1.00 195.78 ? 743  TYR A CD1 1 
ATOM 5810 C CD2 . TYR A 1 743  ? 95.273  137.628 109.760 1.00 201.65 ? 743  TYR A CD2 1 
ATOM 5811 C CE1 . TYR A 1 743  ? 92.750  138.737 109.852 1.00 207.94 ? 743  TYR A CE1 1 
ATOM 5812 C CE2 . TYR A 1 743  ? 94.349  137.326 108.771 1.00 219.44 ? 743  TYR A CE2 1 
ATOM 5813 C CZ  . TYR A 1 743  ? 93.081  137.881 108.817 1.00 216.42 ? 743  TYR A CZ  1 
ATOM 5814 O OH  . TYR A 1 743  ? 92.147  137.586 107.853 1.00 207.47 ? 743  TYR A OH  1 
ATOM 5815 N N   . GLU A 1 834  ? 80.995  121.360 96.664  1.00 301.81 ? 834  GLU A N   1 
ATOM 5816 C CA  . GLU A 1 834  ? 81.441  120.247 95.780  1.00 311.00 ? 834  GLU A CA  1 
ATOM 5817 C C   . GLU A 1 834  ? 82.339  120.774 94.659  1.00 306.72 ? 834  GLU A C   1 
ATOM 5818 O O   . GLU A 1 834  ? 83.057  119.999 94.027  1.00 301.92 ? 834  GLU A O   1 
ATOM 5819 C CB  . GLU A 1 834  ? 80.224  119.511 95.212  1.00 326.19 ? 834  GLU A CB  1 
ATOM 5820 C CG  . GLU A 1 834  ? 80.498  118.063 94.841  1.00 339.47 ? 834  GLU A CG  1 
ATOM 5821 C CD  . GLU A 1 834  ? 80.643  117.122 96.026  1.00 348.23 ? 834  GLU A CD  1 
ATOM 5822 O OE1 . GLU A 1 834  ? 81.584  117.313 96.824  1.00 351.81 ? 834  GLU A OE1 1 
ATOM 5823 O OE2 . GLU A 1 834  ? 79.812  116.200 96.151  1.00 351.85 ? 834  GLU A OE2 1 
ATOM 5824 N N   . LEU A 1 835  ? 82.295  122.088 94.405  1.00 313.82 ? 835  LEU A N   1 
ATOM 5825 C CA  . LEU A 1 835  ? 83.187  122.705 93.437  1.00 325.96 ? 835  LEU A CA  1 
ATOM 5826 C C   . LEU A 1 835  ? 84.634  122.525 93.893  1.00 310.82 ? 835  LEU A C   1 
ATOM 5827 O O   . LEU A 1 835  ? 85.506  122.247 93.076  1.00 306.04 ? 835  LEU A O   1 
ATOM 5828 C CB  . LEU A 1 835  ? 82.826  124.186 93.277  1.00 348.94 ? 835  LEU A CB  1 
ATOM 5829 C CG  . LEU A 1 835  ? 83.522  124.915 92.126  1.00 363.25 ? 835  LEU A CG  1 
ATOM 5830 C CD1 . LEU A 1 835  ? 82.972  124.463 90.779  1.00 363.79 ? 835  LEU A CD1 1 
ATOM 5831 C CD2 . LEU A 1 835  ? 83.384  126.423 92.276  1.00 367.28 ? 835  LEU A CD2 1 
ATOM 5832 N N   . GLU A 1 836  ? 84.879  122.665 95.203  1.00 298.55 ? 836  GLU A N   1 
ATOM 5833 C CA  . GLU A 1 836  ? 86.206  122.468 95.766  1.00 288.69 ? 836  GLU A CA  1 
ATOM 5834 C C   . GLU A 1 836  ? 86.757  121.124 95.297  1.00 276.57 ? 836  GLU A C   1 
ATOM 5835 O O   . GLU A 1 836  ? 87.880  121.054 94.805  1.00 280.56 ? 836  GLU A O   1 
ATOM 5836 C CB  . GLU A 1 836  ? 86.163  122.538 97.295  1.00 290.64 ? 836  GLU A CB  1 
ATOM 5837 C CG  . GLU A 1 836  ? 87.526  122.432 97.969  1.00 289.64 ? 836  GLU A CG  1 
ATOM 5838 C CD  . GLU A 1 836  ? 88.331  123.720 98.052  1.00 286.41 ? 836  GLU A CD  1 
ATOM 5839 O OE1 . GLU A 1 836  ? 89.437  123.765 97.475  1.00 279.46 ? 836  GLU A OE1 1 
ATOM 5840 O OE2 . GLU A 1 836  ? 87.861  124.670 98.713  1.00 284.20 ? 836  GLU A OE2 1 
ATOM 5841 N N   . LYS A 1 837  ? 85.955  120.062 95.443  1.00 264.54 ? 837  LYS A N   1 
ATOM 5842 C CA  . LYS A 1 837  ? 86.337  118.763 94.918  1.00 260.18 ? 837  LYS A CA  1 
ATOM 5843 C C   . LYS A 1 837  ? 86.645  118.915 93.430  1.00 249.88 ? 837  LYS A C   1 
ATOM 5844 O O   . LYS A 1 837  ? 87.674  118.433 92.965  1.00 248.17 ? 837  LYS A O   1 
ATOM 5845 C CB  . LYS A 1 837  ? 85.252  117.711 95.171  1.00 268.14 ? 837  LYS A CB  1 
ATOM 5846 C CG  . LYS A 1 837  ? 85.665  116.280 94.848  1.00 273.03 ? 837  LYS A CG  1 
ATOM 5847 C CD  . LYS A 1 837  ? 84.630  115.233 95.211  1.00 280.32 ? 837  LYS A CD  1 
ATOM 5848 C CE  . LYS A 1 837  ? 84.412  115.092 96.704  1.00 284.24 ? 837  LYS A CE  1 
ATOM 5849 N NZ  . LYS A 1 837  ? 83.412  114.043 97.015  1.00 286.20 ? 837  LYS A NZ  1 
ATOM 5850 N N   . GLN A 1 838  ? 85.768  119.622 92.704  1.00 241.90 ? 838  GLN A N   1 
ATOM 5851 C CA  . GLN A 1 838  ? 85.963  119.863 91.281  1.00 235.49 ? 838  GLN A CA  1 
ATOM 5852 C C   . GLN A 1 838  ? 87.279  120.610 91.055  1.00 225.95 ? 838  GLN A C   1 
ATOM 5853 O O   . GLN A 1 838  ? 88.021  120.285 90.132  1.00 227.87 ? 838  GLN A O   1 
ATOM 5854 C CB  . GLN A 1 838  ? 84.766  120.622 90.696  1.00 236.23 ? 838  GLN A CB  1 
ATOM 5855 C CG  . GLN A 1 838  ? 84.965  121.152 89.277  1.00 233.68 ? 838  GLN A CG  1 
ATOM 5856 C CD  . GLN A 1 838  ? 84.462  120.228 88.191  1.00 233.04 ? 838  GLN A CD  1 
ATOM 5857 O OE1 . GLN A 1 838  ? 85.215  119.782 87.327  1.00 227.88 ? 838  GLN A OE1 1 
ATOM 5858 N NE2 . GLN A 1 838  ? 83.167  119.956 88.208  1.00 240.16 ? 838  GLN A NE2 1 
ATOM 5859 N N   . ILE A 1 839  ? 87.560  121.612 91.895  1.00 215.01 ? 839  ILE A N   1 
ATOM 5860 C CA  . ILE A 1 839  ? 88.811  122.350 91.807  1.00 208.97 ? 839  ILE A CA  1 
ATOM 5861 C C   . ILE A 1 839  ? 89.965  121.382 92.068  1.00 197.42 ? 839  ILE A C   1 
ATOM 5862 O O   . ILE A 1 839  ? 90.992  121.459 91.404  1.00 191.52 ? 839  ILE A O   1 
ATOM 5863 C CB  . ILE A 1 839  ? 88.838  123.561 92.767  1.00 219.48 ? 839  ILE A CB  1 
ATOM 5864 C CG1 . ILE A 1 839  ? 87.662  124.514 92.527  1.00 232.39 ? 839  ILE A CG1 1 
ATOM 5865 C CG2 . ILE A 1 839  ? 90.175  124.290 92.679  1.00 217.14 ? 839  ILE A CG2 1 
ATOM 5866 C CD1 . ILE A 1 839  ? 87.499  125.579 93.591  1.00 239.28 ? 839  ILE A CD1 1 
ATOM 5867 N N   . ILE A 1 840  ? 89.780  120.455 93.017  1.00 195.73 ? 840  ILE A N   1 
ATOM 5868 C CA  . ILE A 1 840  ? 90.833  119.517 93.374  1.00 198.49 ? 840  ILE A CA  1 
ATOM 5869 C C   . ILE A 1 840  ? 91.236  118.703 92.143  1.00 204.71 ? 840  ILE A C   1 
ATOM 5870 O O   . ILE A 1 840  ? 92.425  118.573 91.871  1.00 204.46 ? 840  ILE A O   1 
ATOM 5871 C CB  . ILE A 1 840  ? 90.426  118.624 94.566  1.00 204.91 ? 840  ILE A CB  1 
ATOM 5872 C CG1 . ILE A 1 840  ? 90.311  119.433 95.862  1.00 219.46 ? 840  ILE A CG1 1 
ATOM 5873 C CG2 . ILE A 1 840  ? 91.394  117.460 94.731  1.00 202.63 ? 840  ILE A CG2 1 
ATOM 5874 C CD1 . ILE A 1 840  ? 89.719  118.667 97.026  1.00 223.60 ? 840  ILE A CD1 1 
ATOM 5875 N N   . GLU A 1 841  ? 90.258  118.179 91.390  1.00 206.12 ? 841  GLU A N   1 
ATOM 5876 C CA  . GLU A 1 841  ? 90.544  117.259 90.294  1.00 200.52 ? 841  GLU A CA  1 
ATOM 5877 C C   . GLU A 1 841  ? 91.474  117.891 89.257  1.00 193.13 ? 841  GLU A C   1 
ATOM 5878 O O   . GLU A 1 841  ? 92.388  117.226 88.782  1.00 198.56 ? 841  GLU A O   1 
ATOM 5879 C CB  . GLU A 1 841  ? 89.263  116.764 89.614  1.00 197.87 ? 841  GLU A CB  1 
ATOM 5880 C CG  . GLU A 1 841  ? 88.930  115.312 89.913  1.00 201.43 ? 841  GLU A CG  1 
ATOM 5881 C CD  . GLU A 1 841  ? 89.015  114.908 91.375  1.00 205.75 ? 841  GLU A CD  1 
ATOM 5882 O OE1 . GLU A 1 841  ? 89.764  113.958 91.680  1.00 210.68 ? 841  GLU A OE1 1 
ATOM 5883 O OE2 . GLU A 1 841  ? 88.343  115.548 92.205  1.00 209.08 ? 841  GLU A OE2 1 
ATOM 5884 N N   . ASP A 1 842  ? 91.238  119.159 88.902  1.00 186.53 ? 842  ASP A N   1 
ATOM 5885 C CA  . ASP A 1 842  ? 91.995  119.810 87.841  1.00 183.41 ? 842  ASP A CA  1 
ATOM 5886 C C   . ASP A 1 842  ? 93.417  120.123 88.307  1.00 147.33 ? 842  ASP A C   1 
ATOM 5887 O O   . ASP A 1 842  ? 94.363  120.021 87.528  1.00 146.55 ? 842  ASP A O   1 
ATOM 5888 C CB  . ASP A 1 842  ? 91.282  121.068 87.328  1.00 211.76 ? 842  ASP A CB  1 
ATOM 5889 C CG  . ASP A 1 842  ? 90.903  122.084 88.396  1.00 237.13 ? 842  ASP A CG  1 
ATOM 5890 O OD1 . ASP A 1 842  ? 91.818  122.634 89.044  1.00 247.18 ? 842  ASP A OD1 1 
ATOM 5891 O OD2 . ASP A 1 842  ? 89.691  122.329 88.560  1.00 250.08 ? 842  ASP A OD2 1 
ATOM 5892 N N   . ASN A 1 843  ? 93.552  120.487 89.587  1.00 113.74 ? 843  ASN A N   1 
ATOM 5893 C CA  . ASN A 1 843  ? 94.775  121.064 90.117  1.00 97.87  ? 843  ASN A CA  1 
ATOM 5894 C C   . ASN A 1 843  ? 95.958  120.135 89.863  1.00 75.63  ? 843  ASN A C   1 
ATOM 5895 O O   . ASN A 1 843  ? 95.874  118.941 90.132  1.00 71.96  ? 843  ASN A O   1 
ATOM 5896 C CB  . ASN A 1 843  ? 94.627  121.359 91.611  1.00 113.63 ? 843  ASN A CB  1 
ATOM 5897 C CG  . ASN A 1 843  ? 95.713  122.264 92.150  1.00 136.08 ? 843  ASN A CG  1 
ATOM 5898 O OD1 . ASN A 1 843  ? 96.883  121.885 92.189  1.00 141.30 ? 843  ASN A OD1 1 
ATOM 5899 N ND2 . ASN A 1 843  ? 95.328  123.457 92.579  1.00 144.33 ? 843  ASN A ND2 1 
ATOM 5900 N N   . PRO A 1 844  ? 97.106  120.664 89.380  1.00 74.04  ? 844  PRO A N   1 
ATOM 5901 C CA  . PRO A 1 844  ? 98.310  119.866 89.160  1.00 80.24  ? 844  PRO A CA  1 
ATOM 5902 C C   . PRO A 1 844  ? 98.802  119.148 90.408  1.00 78.50  ? 844  PRO A C   1 
ATOM 5903 O O   . PRO A 1 844  ? 99.147  117.965 90.356  1.00 88.40  ? 844  PRO A O   1 
ATOM 5904 C CB  . PRO A 1 844  ? 99.410  120.867 88.789  1.00 82.55  ? 844  PRO A CB  1 
ATOM 5905 C CG  . PRO A 1 844  ? 98.670  122.096 88.337  1.00 88.84  ? 844  PRO A CG  1 
ATOM 5906 C CD  . PRO A 1 844  ? 97.318  122.071 89.026  1.00 83.37  ? 844  PRO A CD  1 
ATOM 5907 N N   . LEU A 1 845  ? 98.864  119.890 91.516  1.00 63.18  ? 845  LEU A N   1 
ATOM 5908 C CA  . LEU A 1 845  ? 99.223  119.282 92.779  1.00 56.04  ? 845  LEU A CA  1 
ATOM 5909 C C   . LEU A 1 845  ? 98.046  118.465 93.292  1.00 59.09  ? 845  LEU A C   1 
ATOM 5910 O O   . LEU A 1 845  ? 98.220  117.601 94.136  1.00 65.40  ? 845  LEU A O   1 
ATOM 5911 C CB  . LEU A 1 845  ? 99.633  120.362 93.774  1.00 55.74  ? 845  LEU A CB  1 
ATOM 5912 C CG  . LEU A 1 845  ? 100.965 121.055 93.488  1.00 65.51  ? 845  LEU A CG  1 
ATOM 5913 C CD1 . LEU A 1 845  ? 101.712 121.362 94.781  1.00 70.22  ? 845  LEU A CD1 1 
ATOM 5914 C CD2 . LEU A 1 845  ? 101.846 120.244 92.550  1.00 69.57  ? 845  LEU A CD2 1 
ATOM 5915 N N   . GLY A 1 846  ? 96.844  118.724 92.775  1.00 64.39  ? 846  GLY A N   1 
ATOM 5916 C CA  . GLY A 1 846  ? 95.689  117.919 93.137  1.00 67.57  ? 846  GLY A CA  1 
ATOM 5917 C C   . GLY A 1 846  ? 95.422  117.964 94.638  1.00 68.05  ? 846  GLY A C   1 
ATOM 5918 O O   . GLY A 1 846  ? 95.468  119.032 95.244  1.00 74.46  ? 846  GLY A O   1 
ATOM 5919 N N   . SER A 1 847  ? 95.171  116.796 95.232  1.00 68.40  ? 847  SER A N   1 
ATOM 5920 C CA  . SER A 1 847  ? 94.716  116.724 96.609  1.00 73.98  ? 847  SER A CA  1 
ATOM 5921 C C   . SER A 1 847  ? 95.688  117.413 97.566  1.00 67.05  ? 847  SER A C   1 
ATOM 5922 O O   . SER A 1 847  ? 95.248  118.009 98.544  1.00 75.03  ? 847  SER A O   1 
ATOM 5923 C CB  . SER A 1 847  ? 94.473  115.294 97.017  1.00 88.69  ? 847  SER A CB  1 
ATOM 5924 O OG  . SER A 1 847  ? 93.538  114.659 96.151  1.00 91.69  ? 847  SER A OG  1 
ATOM 5925 N N   . LEU A 1 848  ? 96.992  117.352 97.281  1.00 62.02  ? 848  LEU A N   1 
ATOM 5926 C CA  . LEU A 1 848  ? 98.015  117.805 98.214  1.00 70.67  ? 848  LEU A CA  1 
ATOM 5927 C C   . LEU A 1 848  ? 97.878  119.303 98.528  1.00 92.26  ? 848  LEU A C   1 
ATOM 5928 O O   . LEU A 1 848  ? 98.064  119.709 99.676  1.00 106.80 ? 848  LEU A O   1 
ATOM 5929 C CB  . LEU A 1 848  ? 99.388  117.505 97.603  1.00 69.92  ? 848  LEU A CB  1 
ATOM 5930 C CG  . LEU A 1 848  ? 100.529 117.170 98.564  1.00 74.72  ? 848  LEU A CG  1 
ATOM 5931 C CD1 . LEU A 1 848  ? 101.856 117.107 97.821  1.00 71.62  ? 848  LEU A CD1 1 
ATOM 5932 C CD2 . LEU A 1 848  ? 100.622 118.162 99.712  1.00 80.84  ? 848  LEU A CD2 1 
ATOM 5933 N N   . CYS A 1 849  ? 97.525  120.116 97.520  1.00 103.12 ? 849  CYS A N   1 
ATOM 5934 C CA  . CYS A 1 849  ? 97.735  121.561 97.520  1.00 105.93 ? 849  CYS A CA  1 
ATOM 5935 C C   . CYS A 1 849  ? 96.692  122.338 98.326  1.00 106.93 ? 849  CYS A C   1 
ATOM 5936 O O   . CYS A 1 849  ? 95.493  122.099 98.184  1.00 91.46  ? 849  CYS A O   1 
ATOM 5937 C CB  . CYS A 1 849  ? 97.611  122.089 96.102  1.00 116.10 ? 849  CYS A CB  1 
ATOM 5938 S SG  . CYS A 1 849  ? 95.886  122.137 95.541  1.00 128.20 ? 849  CYS A SG  1 
ATOM 5939 N N   . ARG A 1 850  ? 97.146  123.344 99.089  1.00 111.80 ? 850  ARG A N   1 
ATOM 5940 C CA  . ARG A 1 850  ? 96.239  124.252 99.778  1.00 117.73 ? 850  ARG A CA  1 
ATOM 5941 C C   . ARG A 1 850  ? 95.705  125.347 98.854  1.00 114.97 ? 850  ARG A C   1 
ATOM 5942 O O   . ARG A 1 850  ? 94.500  125.597 98.851  1.00 123.01 ? 850  ARG A O   1 
ATOM 5943 C CB  . ARG A 1 850  ? 96.902  124.922 100.986 1.00 126.75 ? 850  ARG A CB  1 
ATOM 5944 C CG  . ARG A 1 850  ? 96.252  124.574 102.318 1.00 143.44 ? 850  ARG A CG  1 
ATOM 5945 C CD  . ARG A 1 850  ? 96.403  125.677 103.353 1.00 154.73 ? 850  ARG A CD  1 
ATOM 5946 N NE  . ARG A 1 850  ? 97.775  126.158 103.477 1.00 160.13 ? 850  ARG A NE  1 
ATOM 5947 C CZ  . ARG A 1 850  ? 98.159  127.423 103.316 1.00 166.46 ? 850  ARG A CZ  1 
ATOM 5948 N NH1 . ARG A 1 850  ? 99.432  127.746 103.460 1.00 169.25 ? 850  ARG A NH1 1 
ATOM 5949 N NH2 . ARG A 1 850  ? 97.276  128.362 103.020 1.00 165.85 ? 850  ARG A NH2 1 
ATOM 5950 N N   . GLY A 1 851  ? 96.597  126.028 98.114  1.00 105.35 ? 851  GLY A N   1 
ATOM 5951 C CA  . GLY A 1 851  ? 96.308  127.370 97.617  1.00 104.59 ? 851  GLY A CA  1 
ATOM 5952 C C   . GLY A 1 851  ? 96.381  127.530 96.098  1.00 106.37 ? 851  GLY A C   1 
ATOM 5953 O O   . GLY A 1 851  ? 97.390  127.193 95.489  1.00 111.21 ? 851  GLY A O   1 
ATOM 5954 N N   . ILE A 1 852  ? 95.306  128.094 95.519  1.00 101.13 ? 852  ILE A N   1 
ATOM 5955 C CA  . ILE A 1 852  ? 95.234  128.461 94.109  1.00 90.40  ? 852  ILE A CA  1 
ATOM 5956 C C   . ILE A 1 852  ? 95.163  129.981 93.999  1.00 87.59  ? 852  ILE A C   1 
ATOM 5957 O O   . ILE A 1 852  ? 94.247  130.597 94.534  1.00 89.58  ? 852  ILE A O   1 
ATOM 5958 C CB  . ILE A 1 852  ? 94.039  127.819 93.365  1.00 93.15  ? 852  ILE A CB  1 
ATOM 5959 C CG1 . ILE A 1 852  ? 92.921  127.322 94.291  1.00 100.00 ? 852  ILE A CG1 1 
ATOM 5960 C CG2 . ILE A 1 852  ? 94.517  126.714 92.437  1.00 99.04  ? 852  ILE A CG2 1 
ATOM 5961 C CD1 . ILE A 1 852  ? 93.111  125.910 94.832  1.00 102.44 ? 852  ILE A CD1 1 
ATOM 5962 N N   . LEU A 1 853  ? 96.139  130.565 93.294  1.00 92.19  ? 853  LEU A N   1 
ATOM 5963 C CA  . LEU A 1 853  ? 96.138  131.976 92.941  1.00 101.18 ? 853  LEU A CA  1 
ATOM 5964 C C   . LEU A 1 853  ? 95.989  132.094 91.430  1.00 118.69 ? 853  LEU A C   1 
ATOM 5965 O O   . LEU A 1 853  ? 96.827  131.563 90.707  1.00 134.84 ? 853  LEU A O   1 
ATOM 5966 C CB  . LEU A 1 853  ? 97.472  132.603 93.355  1.00 99.90  ? 853  LEU A CB  1 
ATOM 5967 C CG  . LEU A 1 853  ? 97.991  132.253 94.747  1.00 114.19 ? 853  LEU A CG  1 
ATOM 5968 C CD1 . LEU A 1 853  ? 99.245  133.054 95.054  1.00 115.19 ? 853  LEU A CD1 1 
ATOM 5969 C CD2 . LEU A 1 853  ? 96.937  132.501 95.820  1.00 126.77 ? 853  LEU A CD2 1 
ATOM 5970 N N   . ASP A 1 854  ? 94.959  132.805 90.956  1.00 129.52 ? 854  ASP A N   1 
ATOM 5971 C CA  . ASP A 1 854  ? 94.846  133.089 89.534  1.00 136.99 ? 854  ASP A CA  1 
ATOM 5972 C C   . ASP A 1 854  ? 96.013  133.992 89.144  1.00 130.21 ? 854  ASP A C   1 
ATOM 5973 O O   . ASP A 1 854  ? 96.233  135.015 89.783  1.00 137.12 ? 854  ASP A O   1 
ATOM 5974 C CB  . ASP A 1 854  ? 93.493  133.717 89.191  1.00 149.46 ? 854  ASP A CB  1 
ATOM 5975 C CG  . ASP A 1 854  ? 92.307  132.885 89.651  1.00 163.53 ? 854  ASP A CG  1 
ATOM 5976 O OD1 . ASP A 1 854  ? 92.530  131.893 90.377  1.00 168.65 ? 854  ASP A OD1 1 
ATOM 5977 O OD2 . ASP A 1 854  ? 91.170  133.236 89.281  1.00 170.75 ? 854  ASP A OD2 1 
ATOM 5978 N N   . LEU A 1 855  ? 96.795  133.589 88.137  1.00 122.82 ? 855  LEU A N   1 
ATOM 5979 C CA  . LEU A 1 855  ? 97.942  134.387 87.744  1.00 124.27 ? 855  LEU A CA  1 
ATOM 5980 C C   . LEU A 1 855  ? 97.477  135.636 86.999  1.00 141.85 ? 855  LEU A C   1 
ATOM 5981 O O   . LEU A 1 855  ? 98.129  136.671 87.088  1.00 152.45 ? 855  LEU A O   1 
ATOM 5982 C CB  . LEU A 1 855  ? 98.921  133.568 86.896  1.00 123.34 ? 855  LEU A CB  1 
ATOM 5983 C CG  . LEU A 1 855  ? 100.128 132.993 87.638  1.00 124.32 ? 855  LEU A CG  1 
ATOM 5984 C CD1 . LEU A 1 855  ? 101.231 132.608 86.655  1.00 127.66 ? 855  LEU A CD1 1 
ATOM 5985 C CD2 . LEU A 1 855  ? 100.658 133.973 88.679  1.00 119.64 ? 855  LEU A CD2 1 
ATOM 5986 N N   . ASN A 1 856  ? 96.337  135.541 86.304  1.00 145.15 ? 856  ASN A N   1 
ATOM 5987 C CA  . ASN A 1 856  ? 95.798  136.645 85.521  1.00 148.84 ? 856  ASN A CA  1 
ATOM 5988 C C   . ASN A 1 856  ? 95.752  137.917 86.362  1.00 137.32 ? 856  ASN A C   1 
ATOM 5989 O O   . ASN A 1 856  ? 96.212  138.974 85.931  1.00 134.02 ? 856  ASN A O   1 
ATOM 5990 C CB  . ASN A 1 856  ? 94.387  136.350 85.004  1.00 161.25 ? 856  ASN A CB  1 
ATOM 5991 C CG  . ASN A 1 856  ? 94.289  135.053 84.229  1.00 175.02 ? 856  ASN A CG  1 
ATOM 5992 O OD1 . ASN A 1 856  ? 94.170  135.064 83.006  1.00 177.84 ? 856  ASN A OD1 1 
ATOM 5993 N ND2 . ASN A 1 856  ? 94.345  133.931 84.929  1.00 180.66 ? 856  ASN A ND2 1 
ATOM 5994 N N   . THR A 1 857  ? 95.180  137.789 87.562  1.00 136.05 ? 857  THR A N   1 
ATOM 5995 C CA  . THR A 1 857  ? 94.902  138.920 88.429  1.00 148.57 ? 857  THR A CA  1 
ATOM 5996 C C   . THR A 1 857  ? 96.195  139.600 88.881  1.00 135.03 ? 857  THR A C   1 
ATOM 5997 O O   . THR A 1 857  ? 96.250  140.827 88.930  1.00 144.01 ? 857  THR A O   1 
ATOM 5998 C CB  . THR A 1 857  ? 94.023  138.485 89.609  1.00 168.87 ? 857  THR A CB  1 
ATOM 5999 O OG1 . THR A 1 857  ? 94.438  137.178 90.007  1.00 177.19 ? 857  THR A OG1 1 
ATOM 6000 C CG2 . THR A 1 857  ? 92.549  138.448 89.265  1.00 175.45 ? 857  THR A CG2 1 
ATOM 6001 N N   . TYR A 1 858  ? 97.230  138.810 89.190  1.00 122.96 ? 858  TYR A N   1 
ATOM 6002 C CA  . TYR A 1 858  ? 98.480  139.341 89.716  1.00 121.05 ? 858  TYR A CA  1 
ATOM 6003 C C   . TYR A 1 858  ? 99.518  139.360 88.596  1.00 120.23 ? 858  TYR A C   1 
ATOM 6004 O O   . TYR A 1 858  ? 99.707  138.358 87.916  1.00 124.15 ? 858  TYR A O   1 
ATOM 6005 C CB  . TYR A 1 858  ? 99.000  138.516 90.902  1.00 122.99 ? 858  TYR A CB  1 
ATOM 6006 C CG  . TYR A 1 858  ? 97.994  138.202 91.985  1.00 135.74 ? 858  TYR A CG  1 
ATOM 6007 C CD1 . TYR A 1 858  ? 96.888  137.404 91.735  1.00 143.41 ? 858  TYR A CD1 1 
ATOM 6008 C CD2 . TYR A 1 858  ? 98.156  138.676 93.276  1.00 153.31 ? 858  TYR A CD2 1 
ATOM 6009 C CE1 . TYR A 1 858  ? 95.963  137.105 92.724  1.00 156.74 ? 858  TYR A CE1 1 
ATOM 6010 C CE2 . TYR A 1 858  ? 97.241  138.390 94.278  1.00 167.11 ? 858  TYR A CE2 1 
ATOM 6011 C CZ  . TYR A 1 858  ? 96.138  137.601 94.003  1.00 168.06 ? 858  TYR A CZ  1 
ATOM 6012 O OH  . TYR A 1 858  ? 95.234  137.327 95.004  1.00 165.66 ? 858  TYR A OH  1 
ATOM 6013 N N   . ASN A 1 859  ? 100.193 140.503 88.420  1.00 125.97 ? 859  ASN A N   1 
ATOM 6014 C CA  . ASN A 1 859  ? 101.190 140.671 87.373  1.00 133.86 ? 859  ASN A CA  1 
ATOM 6015 C C   . ASN A 1 859  ? 102.583 140.511 87.972  1.00 121.16 ? 859  ASN A C   1 
ATOM 6016 O O   . ASN A 1 859  ? 102.934 141.198 88.926  1.00 115.62 ? 859  ASN A O   1 
ATOM 6017 C CB  . ASN A 1 859  ? 101.076 142.034 86.686  1.00 152.73 ? 859  ASN A CB  1 
ATOM 6018 C CG  . ASN A 1 859  ? 99.792  142.211 85.900  1.00 171.59 ? 859  ASN A CG  1 
ATOM 6019 O OD1 . ASN A 1 859  ? 98.941  141.323 85.866  1.00 177.26 ? 859  ASN A OD1 1 
ATOM 6020 N ND2 . ASN A 1 859  ? 99.645  143.359 85.259  1.00 179.25 ? 859  ASN A ND2 1 
ATOM 6021 N N   . VAL A 1 860  ? 103.386 139.626 87.377  1.00 124.64 ? 860  VAL A N   1 
ATOM 6022 C CA  . VAL A 1 860  ? 104.693 139.291 87.918  1.00 133.93 ? 860  VAL A CA  1 
ATOM 6023 C C   . VAL A 1 860  ? 105.630 140.490 87.792  1.00 124.13 ? 860  VAL A C   1 
ATOM 6024 O O   . VAL A 1 860  ? 105.659 141.162 86.765  1.00 131.21 ? 860  VAL A O   1 
ATOM 6025 C CB  . VAL A 1 860  ? 105.284 138.042 87.233  1.00 154.04 ? 860  VAL A CB  1 
ATOM 6026 C CG1 . VAL A 1 860  ? 105.377 138.190 85.719  1.00 162.19 ? 860  VAL A CG1 1 
ATOM 6027 C CG2 . VAL A 1 860  ? 106.639 137.658 87.815  1.00 155.43 ? 860  VAL A CG2 1 
ATOM 6028 N N   . VAL A 1 861  ? 106.407 140.723 88.853  1.00 119.20 ? 861  VAL A N   1 
ATOM 6029 C CA  . VAL A 1 861  ? 107.503 141.674 88.848  1.00 132.60 ? 861  VAL A CA  1 
ATOM 6030 C C   . VAL A 1 861  ? 108.729 140.932 89.366  1.00 131.40 ? 861  VAL A C   1 
ATOM 6031 O O   . VAL A 1 861  ? 108.579 140.001 90.139  1.00 137.33 ? 861  VAL A O   1 
ATOM 6032 C CB  . VAL A 1 861  ? 107.181 142.895 89.733  1.00 158.55 ? 861  VAL A CB  1 
ATOM 6033 C CG1 . VAL A 1 861  ? 108.340 143.881 89.781  1.00 166.70 ? 861  VAL A CG1 1 
ATOM 6034 C CG2 . VAL A 1 861  ? 105.892 143.592 89.312  1.00 169.29 ? 861  VAL A CG2 1 
ATOM 6035 N N   . LYS A 1 862  ? 109.933 141.323 88.946  1.00 137.69 ? 862  LYS A N   1 
ATOM 6036 C CA  . LYS A 1 862  ? 111.136 140.753 89.530  1.00 143.21 ? 862  LYS A CA  1 
ATOM 6037 C C   . LYS A 1 862  ? 111.761 141.822 90.417  1.00 128.42 ? 862  LYS A C   1 
ATOM 6038 O O   . LYS A 1 862  ? 111.865 142.973 90.006  1.00 129.40 ? 862  LYS A O   1 
ATOM 6039 C CB  . LYS A 1 862  ? 112.093 140.247 88.444  1.00 162.43 ? 862  LYS A CB  1 
ATOM 6040 C CG  . LYS A 1 862  ? 113.351 139.563 88.971  1.00 170.28 ? 862  LYS A CG  1 
ATOM 6041 C CD  . LYS A 1 862  ? 114.187 138.860 87.919  1.00 170.82 ? 862  LYS A CD  1 
ATOM 6042 C CE  . LYS A 1 862  ? 114.810 139.804 86.914  1.00 177.14 ? 862  LYS A CE  1 
ATOM 6043 N NZ  . LYS A 1 862  ? 115.665 139.078 85.946  1.00 179.89 ? 862  LYS A NZ  1 
ATOM 6044 N N   . ALA A 1 863  ? 112.159 141.436 91.633  1.00 130.66 ? 863  ALA A N   1 
ATOM 6045 C CA  . ALA A 1 863  ? 112.599 142.404 92.621  1.00 157.53 ? 863  ALA A CA  1 
ATOM 6046 C C   . ALA A 1 863  ? 114.073 142.201 92.965  1.00 173.47 ? 863  ALA A C   1 
ATOM 6047 O O   . ALA A 1 863  ? 114.468 141.138 93.440  1.00 170.49 ? 863  ALA A O   1 
ATOM 6048 C CB  . ALA A 1 863  ? 111.729 142.303 93.844  1.00 169.07 ? 863  ALA A CB  1 
ATOM 6049 N N   . PRO A 1 864  ? 114.932 143.227 92.760  1.00 214.99 ? 864  PRO A N   1 
ATOM 6050 C CA  . PRO A 1 864  ? 116.329 143.157 93.189  1.00 232.81 ? 864  PRO A CA  1 
ATOM 6051 C C   . PRO A 1 864  ? 116.436 143.194 94.712  1.00 231.37 ? 864  PRO A C   1 
ATOM 6052 O O   . PRO A 1 864  ? 115.599 143.814 95.366  1.00 221.26 ? 864  PRO A O   1 
ATOM 6053 C CB  . PRO A 1 864  ? 116.963 144.404 92.555  1.00 246.62 ? 864  PRO A CB  1 
ATOM 6054 C CG  . PRO A 1 864  ? 115.809 145.376 92.429  1.00 248.52 ? 864  PRO A CG  1 
ATOM 6055 C CD  . PRO A 1 864  ? 114.605 144.511 92.116  1.00 236.50 ? 864  PRO A CD  1 
ATOM 6056 N N   . GLN A 1 865  ? 117.470 142.526 95.245  1.00 236.45 ? 865  GLN A N   1 
ATOM 6057 C CA  . GLN A 1 865  ? 117.760 142.467 96.672  1.00 241.71 ? 865  GLN A CA  1 
ATOM 6058 C C   . GLN A 1 865  ? 116.834 141.445 97.329  1.00 232.35 ? 865  GLN A C   1 
ATOM 6059 O O   . GLN A 1 865  ? 116.006 140.833 96.658  1.00 234.27 ? 865  GLN A O   1 
ATOM 6060 C CB  . GLN A 1 865  ? 117.651 143.846 97.333  1.00 259.88 ? 865  GLN A CB  1 
ATOM 6061 C CG  . GLN A 1 865  ? 118.572 144.894 96.725  1.00 282.78 ? 865  GLN A CG  1 
ATOM 6062 C CD  . GLN A 1 865  ? 120.027 144.511 96.849  1.00 305.86 ? 865  GLN A CD  1 
ATOM 6063 O OE1 . GLN A 1 865  ? 120.546 144.317 97.946  1.00 320.74 ? 865  GLN A OE1 1 
ATOM 6064 N NE2 . GLN A 1 865  ? 120.695 144.385 95.714  1.00 313.75 ? 865  GLN A NE2 1 
ATOM 6065 N N   . GLY A 1 866  ? 117.005 141.253 98.645  1.00 220.33 ? 866  GLY A N   1 
ATOM 6066 C CA  . GLY A 1 866  ? 116.235 140.276 99.400  1.00 205.53 ? 866  GLY A CA  1 
ATOM 6067 C C   . GLY A 1 866  ? 115.422 140.919 100.521 1.00 179.71 ? 866  GLY A C   1 
ATOM 6068 O O   . GLY A 1 866  ? 115.975 141.642 101.347 1.00 185.95 ? 866  GLY A O   1 
ATOM 6069 N N   . LYS A 1 867  ? 114.114 140.642 100.549 1.00 155.55 ? 867  LYS A N   1 
ATOM 6070 C CA  . LYS A 1 867  ? 113.289 140.997 101.689 1.00 150.05 ? 867  LYS A CA  1 
ATOM 6071 C C   . LYS A 1 867  ? 113.398 139.871 102.708 1.00 141.53 ? 867  LYS A C   1 
ATOM 6072 O O   . LYS A 1 867  ? 113.205 138.719 102.346 1.00 147.71 ? 867  LYS A O   1 
ATOM 6073 C CB  . LYS A 1 867  ? 111.829 141.194 101.277 1.00 152.75 ? 867  LYS A CB  1 
ATOM 6074 C CG  . LYS A 1 867  ? 110.927 141.704 102.393 1.00 161.63 ? 867  LYS A CG  1 
ATOM 6075 C CD  . LYS A 1 867  ? 109.476 141.889 102.002 1.00 166.17 ? 867  LYS A CD  1 
ATOM 6076 C CE  . LYS A 1 867  ? 109.269 142.872 100.868 1.00 171.56 ? 867  LYS A CE  1 
ATOM 6077 N NZ  . LYS A 1 867  ? 107.835 143.010 100.519 1.00 171.89 ? 867  LYS A NZ  1 
ATOM 6078 N N   . ASN A 1 868  ? 113.726 140.204 103.961 1.00 146.02 ? 868  ASN A N   1 
ATOM 6079 C CA  . ASN A 1 868  ? 113.870 139.207 105.010 1.00 158.23 ? 868  ASN A CA  1 
ATOM 6080 C C   . ASN A 1 868  ? 114.878 138.130 104.609 1.00 171.64 ? 868  ASN A C   1 
ATOM 6081 O O   . ASN A 1 868  ? 114.618 136.949 104.828 1.00 177.48 ? 868  ASN A O   1 
ATOM 6082 C CB  . ASN A 1 868  ? 112.541 138.511 105.319 1.00 160.42 ? 868  ASN A CB  1 
ATOM 6083 C CG  . ASN A 1 868  ? 111.432 139.461 105.709 1.00 161.51 ? 868  ASN A CG  1 
ATOM 6084 O OD1 . ASN A 1 868  ? 111.536 140.164 106.711 1.00 177.36 ? 868  ASN A OD1 1 
ATOM 6085 N ND2 . ASN A 1 868  ? 110.366 139.488 104.927 1.00 151.91 ? 868  ASN A ND2 1 
ATOM 6086 N N   . GLN A 1 869  ? 116.030 138.530 104.048 1.00 184.47 ? 869  GLN A N   1 
ATOM 6087 C CA  . GLN A 1 869  ? 117.019 137.590 103.529 1.00 205.97 ? 869  GLN A CA  1 
ATOM 6088 C C   . GLN A 1 869  ? 116.402 136.867 102.333 1.00 206.51 ? 869  GLN A C   1 
ATOM 6089 O O   . GLN A 1 869  ? 115.707 137.500 101.548 1.00 214.67 ? 869  GLN A O   1 
ATOM 6090 C CB  . GLN A 1 869  ? 117.502 136.640 104.632 1.00 227.52 ? 869  GLN A CB  1 
ATOM 6091 C CG  . GLN A 1 869  ? 118.037 137.355 105.868 1.00 241.99 ? 869  GLN A CG  1 
ATOM 6092 C CD  . GLN A 1 869  ? 118.329 136.404 107.003 1.00 257.33 ? 869  GLN A CD  1 
ATOM 6093 O OE1 . GLN A 1 869  ? 119.172 135.516 106.894 1.00 269.48 ? 869  GLN A OE1 1 
ATOM 6094 N NE2 . GLN A 1 869  ? 117.630 136.586 108.112 1.00 260.44 ? 869  GLN A NE2 1 
ATOM 6095 N N   . LYS A 1 870  ? 116.665 135.565 102.156 1.00 189.30 ? 870  LYS A N   1 
ATOM 6096 C CA  . LYS A 1 870  ? 116.038 134.842 101.063 1.00 172.74 ? 870  LYS A CA  1 
ATOM 6097 C C   . LYS A 1 870  ? 116.110 135.745 99.830  1.00 179.60 ? 870  LYS A C   1 
ATOM 6098 O O   . LYS A 1 870  ? 115.108 135.963 99.154  1.00 177.74 ? 870  LYS A O   1 
ATOM 6099 C CB  . LYS A 1 870  ? 114.605 134.445 101.449 1.00 151.57 ? 870  LYS A CB  1 
ATOM 6100 C CG  . LYS A 1 870  ? 114.498 133.346 102.497 1.00 146.06 ? 870  LYS A CG  1 
ATOM 6101 C CD  . LYS A 1 870  ? 115.094 133.697 103.848 1.00 151.49 ? 870  LYS A CD  1 
ATOM 6102 C CE  . LYS A 1 870  ? 115.089 132.537 104.824 1.00 155.82 ? 870  LYS A CE  1 
ATOM 6103 N NZ  . LYS A 1 870  ? 113.718 132.127 105.211 1.00 151.39 ? 870  LYS A NZ  1 
ATOM 6104 N N   . SER A 1 871  ? 117.313 136.297 99.603  1.00 176.03 ? 871  SER A N   1 
ATOM 6105 C CA  . SER A 1 871  ? 117.572 137.375 98.658  1.00 168.42 ? 871  SER A CA  1 
ATOM 6106 C C   . SER A 1 871  ? 116.911 137.153 97.299  1.00 146.59 ? 871  SER A C   1 
ATOM 6107 O O   . SER A 1 871  ? 116.029 137.915 96.909  1.00 142.11 ? 871  SER A O   1 
ATOM 6108 C CB  . SER A 1 871  ? 119.054 137.596 98.505  1.00 172.08 ? 871  SER A CB  1 
ATOM 6109 O OG  . SER A 1 871  ? 119.638 137.954 99.748  1.00 173.89 ? 871  SER A OG  1 
ATOM 6110 N N   . PHE A 1 872  ? 117.358 136.141 96.553  1.00 129.74 ? 872  PHE A N   1 
ATOM 6111 C CA  . PHE A 1 872  ? 116.764 135.905 95.250  1.00 119.98 ? 872  PHE A CA  1 
ATOM 6112 C C   . PHE A 1 872  ? 115.264 135.903 95.492  1.00 102.22 ? 872  PHE A C   1 
ATOM 6113 O O   . PHE A 1 872  ? 114.818 135.251 96.426  1.00 99.66  ? 872  PHE A O   1 
ATOM 6114 C CB  . PHE A 1 872  ? 117.261 134.595 94.631  1.00 134.84 ? 872  PHE A CB  1 
ATOM 6115 C CG  . PHE A 1 872  ? 118.755 134.475 94.443  1.00 159.87 ? 872  PHE A CG  1 
ATOM 6116 C CD1 . PHE A 1 872  ? 119.613 135.533 94.717  1.00 174.42 ? 872  PHE A CD1 1 
ATOM 6117 C CD2 . PHE A 1 872  ? 119.310 133.287 93.987  1.00 174.83 ? 872  PHE A CD2 1 
ATOM 6118 C CE1 . PHE A 1 872  ? 120.983 135.400 94.543  1.00 181.82 ? 872  PHE A CE1 1 
ATOM 6119 C CE2 . PHE A 1 872  ? 120.681 133.154 93.822  1.00 177.93 ? 872  PHE A CE2 1 
ATOM 6120 C CZ  . PHE A 1 872  ? 121.515 134.212 94.096  1.00 179.91 ? 872  PHE A CZ  1 
ATOM 6121 N N   . VAL A 1 873  ? 114.505 136.711 94.747  1.00 96.72  ? 873  VAL A N   1 
ATOM 6122 C CA  . VAL A 1 873  ? 113.097 136.881 95.073  1.00 101.81 ? 873  VAL A CA  1 
ATOM 6123 C C   . VAL A 1 873  ? 112.316 137.420 93.879  1.00 94.44  ? 873  VAL A C   1 
ATOM 6124 O O   . VAL A 1 873  ? 112.885 137.996 92.955  1.00 102.94 ? 873  VAL A O   1 
ATOM 6125 C CB  . VAL A 1 873  ? 112.919 137.798 96.299  1.00 116.37 ? 873  VAL A CB  1 
ATOM 6126 C CG1 . VAL A 1 873  ? 113.466 139.193 96.038  1.00 128.30 ? 873  VAL A CG1 1 
ATOM 6127 C CG2 . VAL A 1 873  ? 111.468 137.874 96.758  1.00 115.28 ? 873  VAL A CG2 1 
ATOM 6128 N N   . PHE A 1 874  ? 110.997 137.210 93.937  1.00 88.91  ? 874  PHE A N   1 
ATOM 6129 C CA  . PHE A 1 874  ? 110.060 137.736 92.963  1.00 92.50  ? 874  PHE A CA  1 
ATOM 6130 C C   . PHE A 1 874  ? 108.773 138.079 93.714  1.00 92.89  ? 874  PHE A C   1 
ATOM 6131 O O   . PHE A 1 874  ? 108.612 137.677 94.861  1.00 95.95  ? 874  PHE A O   1 
ATOM 6132 C CB  . PHE A 1 874  ? 109.947 136.749 91.792  1.00 102.64 ? 874  PHE A CB  1 
ATOM 6133 C CG  . PHE A 1 874  ? 108.888 135.675 91.864  1.00 116.12 ? 874  PHE A CG  1 
ATOM 6134 C CD1 . PHE A 1 874  ? 107.544 135.997 91.739  1.00 126.16 ? 874  PHE A CD1 1 
ATOM 6135 C CD2 . PHE A 1 874  ? 109.234 134.335 91.984  1.00 121.92 ? 874  PHE A CD2 1 
ATOM 6136 C CE1 . PHE A 1 874  ? 106.571 135.010 91.772  1.00 136.98 ? 874  PHE A CE1 1 
ATOM 6137 C CE2 . PHE A 1 874  ? 108.260 133.349 92.018  1.00 127.44 ? 874  PHE A CE2 1 
ATOM 6138 C CZ  . PHE A 1 874  ? 106.931 133.687 91.908  1.00 136.76 ? 874  PHE A CZ  1 
ATOM 6139 N N   . ILE A 1 875  ? 107.897 138.877 93.089  1.00 102.66 ? 875  ILE A N   1 
ATOM 6140 C CA  . ILE A 1 875  ? 106.675 139.367 93.715  1.00 112.61 ? 875  ILE A CA  1 
ATOM 6141 C C   . ILE A 1 875  ? 105.529 139.246 92.710  1.00 104.49 ? 875  ILE A C   1 
ATOM 6142 O O   . ILE A 1 875  ? 105.772 139.212 91.508  1.00 109.56 ? 875  ILE A O   1 
ATOM 6143 C CB  . ILE A 1 875  ? 106.867 140.820 94.215  1.00 129.77 ? 875  ILE A CB  1 
ATOM 6144 C CG1 . ILE A 1 875  ? 107.505 140.886 95.608  1.00 138.23 ? 875  ILE A CG1 1 
ATOM 6145 C CG2 . ILE A 1 875  ? 105.564 141.604 94.192  1.00 128.21 ? 875  ILE A CG2 1 
ATOM 6146 C CD1 . ILE A 1 875  ? 109.016 140.802 95.627  1.00 135.01 ? 875  ILE A CD1 1 
ATOM 6147 N N   . LEU A 1 876  ? 104.284 139.185 93.207  1.00 104.96 ? 876  LEU A N   1 
ATOM 6148 C CA  . LEU A 1 876  ? 103.110 139.158 92.346  1.00 120.33 ? 876  LEU A CA  1 
ATOM 6149 C C   . LEU A 1 876  ? 102.098 140.212 92.790  1.00 135.23 ? 876  LEU A C   1 
ATOM 6150 O O   . LEU A 1 876  ? 101.040 139.869 93.308  1.00 141.41 ? 876  LEU A O   1 
ATOM 6151 C CB  . LEU A 1 876  ? 102.487 137.760 92.389  1.00 126.21 ? 876  LEU A CB  1 
ATOM 6152 C CG  . LEU A 1 876  ? 103.331 136.630 91.799  1.00 145.88 ? 876  LEU A CG  1 
ATOM 6153 C CD1 . LEU A 1 876  ? 102.561 135.319 91.826  1.00 154.93 ? 876  LEU A CD1 1 
ATOM 6154 C CD2 . LEU A 1 876  ? 103.775 136.940 90.373  1.00 154.26 ? 876  LEU A CD2 1 
ATOM 6155 N N   . GLU A 1 877  ? 102.419 141.488 92.540  1.00 141.13 ? 877  GLU A N   1 
ATOM 6156 C CA  . GLU A 1 877  ? 101.567 142.607 92.918  1.00 138.88 ? 877  GLU A CA  1 
ATOM 6157 C C   . GLU A 1 877  ? 100.245 142.496 92.163  1.00 137.58 ? 877  GLU A C   1 
ATOM 6158 O O   . GLU A 1 877  ? 100.254 142.376 90.945  1.00 142.40 ? 877  GLU A O   1 
ATOM 6159 C CB  . GLU A 1 877  ? 102.222 143.948 92.572  1.00 145.94 ? 877  GLU A CB  1 
ATOM 6160 C CG  . GLU A 1 877  ? 103.717 144.002 92.832  1.00 161.81 ? 877  GLU A CG  1 
ATOM 6161 C CD  . GLU A 1 877  ? 104.362 145.355 92.575  1.00 181.80 ? 877  GLU A CD  1 
ATOM 6162 O OE1 . GLU A 1 877  ? 105.055 145.859 93.482  1.00 185.81 ? 877  GLU A OE1 1 
ATOM 6163 O OE2 . GLU A 1 877  ? 104.163 145.908 91.475  1.00 191.56 ? 877  GLU A OE2 1 
ATOM 6164 N N   . PRO A 1 878  ? 99.070  142.512 92.833  1.00 142.28 ? 878  PRO A N   1 
ATOM 6165 C CA  . PRO A 1 878  ? 97.792  142.428 92.127  1.00 148.96 ? 878  PRO A CA  1 
ATOM 6166 C C   . PRO A 1 878  ? 97.441  143.797 91.560  1.00 167.58 ? 878  PRO A C   1 
ATOM 6167 O O   . PRO A 1 878  ? 97.739  144.807 92.191  1.00 176.99 ? 878  PRO A O   1 
ATOM 6168 C CB  . PRO A 1 878  ? 96.803  142.017 93.224  1.00 143.47 ? 878  PRO A CB  1 
ATOM 6169 C CG  . PRO A 1 878  ? 97.385  142.641 94.471  1.00 144.86 ? 878  PRO A CG  1 
ATOM 6170 C CD  . PRO A 1 878  ? 98.892  142.638 94.287  1.00 143.74 ? 878  PRO A CD  1 
ATOM 6171 N N   . LYS A 1 879  ? 96.799  143.826 90.388  1.00 188.88 ? 879  LYS A N   1 
ATOM 6172 C CA  . LYS A 1 879  ? 96.461  145.089 89.751  1.00 216.03 ? 879  LYS A CA  1 
ATOM 6173 C C   . LYS A 1 879  ? 95.551  145.902 90.675  1.00 235.45 ? 879  LYS A C   1 
ATOM 6174 O O   . LYS A 1 879  ? 95.786  147.091 90.875  1.00 239.22 ? 879  LYS A O   1 
ATOM 6175 C CB  . LYS A 1 879  ? 95.835  144.845 88.375  1.00 229.88 ? 879  LYS A CB  1 
ATOM 6176 C CG  . LYS A 1 879  ? 96.748  144.133 87.384  1.00 241.31 ? 879  LYS A CG  1 
ATOM 6177 C CD  . LYS A 1 879  ? 96.160  143.949 85.999  1.00 251.20 ? 879  LYS A CD  1 
ATOM 6178 C CE  . LYS A 1 879  ? 94.901  143.108 85.977  1.00 254.67 ? 879  LYS A CE  1 
ATOM 6179 N NZ  . LYS A 1 879  ? 95.115  141.772 86.581  1.00 255.69 ? 879  LYS A NZ  1 
ATOM 6180 N N   . GLN A 1 880  ? 94.528  145.249 91.245  1.00 249.71 ? 880  GLN A N   1 
ATOM 6181 C CA  . GLN A 1 880  ? 93.660  145.868 92.238  1.00 257.28 ? 880  GLN A CA  1 
ATOM 6182 C C   . GLN A 1 880  ? 94.490  146.068 93.509  1.00 273.33 ? 880  GLN A C   1 
ATOM 6183 O O   . GLN A 1 880  ? 95.268  145.192 93.874  1.00 287.37 ? 880  GLN A O   1 
ATOM 6184 C CB  . GLN A 1 880  ? 92.406  145.001 92.413  1.00 247.04 ? 880  GLN A CB  1 
ATOM 6185 C CG  . GLN A 1 880  ? 91.299  145.633 93.251  1.00 240.08 ? 880  GLN A CG  1 
ATOM 6186 C CD  . GLN A 1 880  ? 91.655  145.758 94.714  1.00 237.09 ? 880  GLN A CD  1 
ATOM 6187 O OE1 . GLN A 1 880  ? 91.678  146.851 95.278  1.00 232.52 ? 880  GLN A OE1 1 
ATOM 6188 N NE2 . GLN A 1 880  ? 91.943  144.635 95.347  1.00 239.32 ? 880  GLN A NE2 1 
ATOM 6189 N N   . GLN A 1 881  ? 94.355  147.237 94.156  1.00 271.90 ? 881  GLN A N   1 
ATOM 6190 C CA  . GLN A 1 881  ? 95.229  147.633 95.254  1.00 270.29 ? 881  GLN A CA  1 
ATOM 6191 C C   . GLN A 1 881  ? 95.053  146.731 96.479  1.00 252.33 ? 881  GLN A C   1 
ATOM 6192 O O   . GLN A 1 881  ? 96.038  146.417 97.144  1.00 239.52 ? 881  GLN A O   1 
ATOM 6193 C CB  . GLN A 1 881  ? 95.003  149.103 95.627  1.00 289.62 ? 881  GLN A CB  1 
ATOM 6194 C CG  . GLN A 1 881  ? 93.586  149.436 96.083  1.00 311.52 ? 881  GLN A CG  1 
ATOM 6195 C CD  . GLN A 1 881  ? 93.445  150.884 96.484  1.00 331.01 ? 881  GLN A CD  1 
ATOM 6196 O OE1 . GLN A 1 881  ? 92.681  151.642 95.889  1.00 342.31 ? 881  GLN A OE1 1 
ATOM 6197 N NE2 . GLN A 1 881  ? 94.186  151.282 97.505  1.00 337.35 ? 881  GLN A NE2 1 
ATOM 6198 N N   . GLY A 1 882  ? 93.808  146.343 96.783  1.00 249.94 ? 882  GLY A N   1 
ATOM 6199 C CA  . GLY A 1 882  ? 93.444  145.653 98.016  1.00 245.91 ? 882  GLY A CA  1 
ATOM 6200 C C   . GLY A 1 882  ? 94.113  144.294 98.245  1.00 228.40 ? 882  GLY A C   1 
ATOM 6201 O O   . GLY A 1 882  ? 94.554  144.002 99.360  1.00 236.63 ? 882  GLY A O   1 
ATOM 6202 N N   . ASP A 1 883  ? 94.154  143.435 97.219  1.00 197.70 ? 883  ASP A N   1 
ATOM 6203 C CA  . ASP A 1 883  ? 94.606  142.065 97.402  1.00 171.44 ? 883  ASP A CA  1 
ATOM 6204 C C   . ASP A 1 883  ? 96.068  142.082 97.845  1.00 158.48 ? 883  ASP A C   1 
ATOM 6205 O O   . ASP A 1 883  ? 96.853  142.908 97.390  1.00 157.99 ? 883  ASP A O   1 
ATOM 6206 C CB  . ASP A 1 883  ? 94.329  141.229 96.150  1.00 168.25 ? 883  ASP A CB  1 
ATOM 6207 C CG  . ASP A 1 883  ? 92.836  141.080 95.895  1.00 164.44 ? 883  ASP A CG  1 
ATOM 6208 O OD1 . ASP A 1 883  ? 92.164  142.122 95.727  1.00 154.49 ? 883  ASP A OD1 1 
ATOM 6209 O OD2 . ASP A 1 883  ? 92.348  139.934 95.898  1.00 165.39 ? 883  ASP A OD2 1 
ATOM 6210 N N   . PRO A 1 884  ? 96.470  141.199 98.784  1.00 149.30 ? 884  PRO A N   1 
ATOM 6211 C CA  . PRO A 1 884  ? 97.822  141.236 99.350  1.00 137.67 ? 884  PRO A CA  1 
ATOM 6212 C C   . PRO A 1 884  ? 98.922  140.838 98.370  1.00 114.36 ? 884  PRO A C   1 
ATOM 6213 O O   . PRO A 1 884  ? 98.724  139.950 97.547  1.00 117.24 ? 884  PRO A O   1 
ATOM 6214 C CB  . PRO A 1 884  ? 97.753  140.205 100.487 1.00 155.80 ? 884  PRO A CB  1 
ATOM 6215 C CG  . PRO A 1 884  ? 96.652  139.255 100.058 1.00 164.37 ? 884  PRO A CG  1 
ATOM 6216 C CD  . PRO A 1 884  ? 95.635  140.134 99.360  1.00 156.30 ? 884  PRO A CD  1 
ATOM 6217 N N   . PRO A 1 885  ? 100.115 141.466 98.432  1.00 104.98 ? 885  PRO A N   1 
ATOM 6218 C CA  . PRO A 1 885  ? 101.241 141.057 97.594  1.00 112.14 ? 885  PRO A CA  1 
ATOM 6219 C C   . PRO A 1 885  ? 101.947 139.794 98.092  1.00 124.00 ? 885  PRO A C   1 
ATOM 6220 O O   . PRO A 1 885  ? 102.853 139.869 98.921  1.00 133.42 ? 885  PRO A O   1 
ATOM 6221 C CB  . PRO A 1 885  ? 102.173 142.276 97.671  1.00 109.52 ? 885  PRO A CB  1 
ATOM 6222 C CG  . PRO A 1 885  ? 101.922 142.833 99.050  1.00 109.86 ? 885  PRO A CG  1 
ATOM 6223 C CD  . PRO A 1 885  ? 100.443 142.608 99.295  1.00 106.48 ? 885  PRO A CD  1 
ATOM 6224 N N   . VAL A 1 886  ? 101.542 138.633 97.561  1.00 119.86 ? 886  VAL A N   1 
ATOM 6225 C CA  . VAL A 1 886  ? 102.230 137.380 97.837  1.00 111.13 ? 886  VAL A CA  1 
ATOM 6226 C C   . VAL A 1 886  ? 103.662 137.515 97.323  1.00 94.82  ? 886  VAL A C   1 
ATOM 6227 O O   . VAL A 1 886  ? 103.901 138.213 96.342  1.00 98.48  ? 886  VAL A O   1 
ATOM 6228 C CB  . VAL A 1 886  ? 101.502 136.178 97.202  1.00 123.17 ? 886  VAL A CB  1 
ATOM 6229 C CG1 . VAL A 1 886  ? 102.124 134.851 97.627  1.00 131.03 ? 886  VAL A CG1 1 
ATOM 6230 C CG2 . VAL A 1 886  ? 100.006 136.196 97.503  1.00 125.61 ? 886  VAL A CG2 1 
ATOM 6231 N N   . GLU A 1 887  ? 104.616 136.878 98.004  1.00 87.65  ? 887  GLU A N   1 
ATOM 6232 C CA  . GLU A 1 887  ? 106.018 137.089 97.690  1.00 97.65  ? 887  GLU A CA  1 
ATOM 6233 C C   . GLU A 1 887  ? 106.771 135.760 97.612  1.00 106.42 ? 887  GLU A C   1 
ATOM 6234 O O   . GLU A 1 887  ? 107.612 135.477 98.462  1.00 110.36 ? 887  GLU A O   1 
ATOM 6235 C CB  . GLU A 1 887  ? 106.635 138.010 98.741  1.00 117.06 ? 887  GLU A CB  1 
ATOM 6236 C CG  . GLU A 1 887  ? 108.074 138.401 98.439  1.00 150.41 ? 887  GLU A CG  1 
ATOM 6237 C CD  . GLU A 1 887  ? 108.699 139.351 99.446  1.00 182.13 ? 887  GLU A CD  1 
ATOM 6238 O OE1 . GLU A 1 887  ? 109.889 139.685 99.282  1.00 192.75 ? 887  GLU A OE1 1 
ATOM 6239 O OE2 . GLU A 1 887  ? 107.992 139.765 100.384 1.00 196.79 ? 887  GLU A OE2 1 
ATOM 6240 N N   . PHE A 1 888  ? 106.498 134.970 96.563  1.00 100.47 ? 888  PHE A N   1 
ATOM 6241 C CA  . PHE A 1 888  ? 107.236 133.739 96.308  1.00 87.68  ? 888  PHE A CA  1 
ATOM 6242 C C   . PHE A 1 888  ? 108.698 134.058 95.999  1.00 85.10  ? 888  PHE A C   1 
ATOM 6243 O O   . PHE A 1 888  ? 108.974 134.976 95.232  1.00 92.97  ? 888  PHE A O   1 
ATOM 6244 C CB  . PHE A 1 888  ? 106.649 132.987 95.116  1.00 86.03  ? 888  PHE A CB  1 
ATOM 6245 C CG  . PHE A 1 888  ? 105.175 132.688 95.188  1.00 96.72  ? 888  PHE A CG  1 
ATOM 6246 C CD1 . PHE A 1 888  ? 104.642 131.932 96.219  1.00 104.36 ? 888  PHE A CD1 1 
ATOM 6247 C CD2 . PHE A 1 888  ? 104.320 133.140 94.194  1.00 111.82 ? 888  PHE A CD2 1 
ATOM 6248 C CE1 . PHE A 1 888  ? 103.283 131.648 96.256  1.00 114.72 ? 888  PHE A CE1 1 
ATOM 6249 C CE2 . PHE A 1 888  ? 102.963 132.858 94.239  1.00 118.82 ? 888  PHE A CE2 1 
ATOM 6250 C CZ  . PHE A 1 888  ? 102.448 132.113 95.271  1.00 118.78 ? 888  PHE A CZ  1 
ATOM 6251 N N   . ALA A 1 889  ? 109.621 133.286 96.588  1.00 87.72  ? 889  ALA A N   1 
ATOM 6252 C CA  . ALA A 1 889  ? 111.050 133.500 96.417  1.00 97.43  ? 889  ALA A CA  1 
ATOM 6253 C C   . ALA A 1 889  ? 111.791 132.165 96.402  1.00 113.52 ? 889  ALA A C   1 
ATOM 6254 O O   . ALA A 1 889  ? 111.278 131.168 96.898  1.00 117.63 ? 889  ALA A O   1 
ATOM 6255 C CB  . ALA A 1 889  ? 111.559 134.384 97.523  1.00 98.25  ? 889  ALA A CB  1 
ATOM 6256 N N   . THR A 1 890  ? 113.020 132.164 95.867  1.00 128.95 ? 890  THR A N   1 
ATOM 6257 C CA  . THR A 1 890  ? 113.729 130.930 95.562  1.00 144.58 ? 890  THR A CA  1 
ATOM 6258 C C   . THR A 1 890  ? 115.206 131.009 95.945  1.00 144.41 ? 890  THR A C   1 
ATOM 6259 O O   . THR A 1 890  ? 115.816 132.074 95.952  1.00 136.64 ? 890  THR A O   1 
ATOM 6260 C CB  . THR A 1 890  ? 113.607 130.575 94.075  1.00 156.28 ? 890  THR A CB  1 
ATOM 6261 O OG1 . THR A 1 890  ? 114.765 129.814 93.733  1.00 159.09 ? 890  THR A OG1 1 
ATOM 6262 C CG2 . THR A 1 890  ? 113.500 131.784 93.170  1.00 162.54 ? 890  THR A CG2 1 
ATOM 6263 N N   . ASP A 1 891  ? 115.781 129.829 96.193  1.00 157.39 ? 891  ASP A N   1 
ATOM 6264 C CA  . ASP A 1 891  ? 117.181 129.680 96.558  1.00 170.21 ? 891  ASP A CA  1 
ATOM 6265 C C   . ASP A 1 891  ? 118.073 129.780 95.322  1.00 167.55 ? 891  ASP A C   1 
ATOM 6266 O O   . ASP A 1 891  ? 119.179 130.308 95.412  1.00 163.81 ? 891  ASP A O   1 
ATOM 6267 C CB  . ASP A 1 891  ? 117.417 128.356 97.291  1.00 187.79 ? 891  ASP A CB  1 
ATOM 6268 C CG  . ASP A 1 891  ? 116.591 127.193 96.762  1.00 204.50 ? 891  ASP A CG  1 
ATOM 6269 O OD1 . ASP A 1 891  ? 115.658 127.446 95.968  1.00 212.49 ? 891  ASP A OD1 1 
ATOM 6270 O OD2 . ASP A 1 891  ? 116.879 126.045 97.154  1.00 212.55 ? 891  ASP A OD2 1 
ATOM 6271 N N   . ARG A 1 892  ? 117.595 129.257 94.183  1.00 178.60 ? 892  ARG A N   1 
ATOM 6272 C CA  . ARG A 1 892  ? 118.367 129.204 92.949  1.00 195.92 ? 892  ARG A CA  1 
ATOM 6273 C C   . ARG A 1 892  ? 117.896 130.290 91.983  1.00 199.76 ? 892  ARG A C   1 
ATOM 6274 O O   . ARG A 1 892  ? 116.704 130.391 91.704  1.00 202.28 ? 892  ARG A O   1 
ATOM 6275 C CB  . ARG A 1 892  ? 118.194 127.842 92.271  1.00 212.16 ? 892  ARG A CB  1 
ATOM 6276 C CG  . ARG A 1 892  ? 118.663 126.653 93.096  1.00 230.72 ? 892  ARG A CG  1 
ATOM 6277 C CD  . ARG A 1 892  ? 118.432 125.338 92.374  1.00 244.45 ? 892  ARG A CD  1 
ATOM 6278 N NE  . ARG A 1 892  ? 119.110 125.277 91.084  1.00 260.29 ? 892  ARG A NE  1 
ATOM 6279 C CZ  . ARG A 1 892  ? 120.048 124.392 90.760  1.00 279.54 ? 892  ARG A CZ  1 
ATOM 6280 N NH1 . ARG A 1 892  ? 120.592 124.419 89.557  1.00 289.04 ? 892  ARG A NH1 1 
ATOM 6281 N NH2 . ARG A 1 892  ? 120.437 123.479 91.634  1.00 282.21 ? 892  ARG A NH2 1 
ATOM 6282 N N   . VAL A 1 893  ? 118.843 131.076 91.456  1.00 196.29 ? 893  VAL A N   1 
ATOM 6283 C CA  . VAL A 1 893  ? 118.535 132.159 90.532  1.00 194.57 ? 893  VAL A CA  1 
ATOM 6284 C C   . VAL A 1 893  ? 117.897 131.588 89.267  1.00 189.21 ? 893  VAL A C   1 
ATOM 6285 O O   . VAL A 1 893  ? 116.943 132.147 88.732  1.00 173.74 ? 893  VAL A O   1 
ATOM 6286 C CB  . VAL A 1 893  ? 119.780 133.006 90.193  1.00 200.47 ? 893  VAL A CB  1 
ATOM 6287 C CG1 . VAL A 1 893  ? 120.995 132.164 89.819  1.00 199.80 ? 893  VAL A CG1 1 
ATOM 6288 C CG2 . VAL A 1 893  ? 119.479 134.019 89.098  1.00 205.01 ? 893  VAL A CG2 1 
ATOM 6289 N N   . GLU A 1 894  ? 118.448 130.468 88.799  1.00 202.20 ? 894  GLU A N   1 
ATOM 6290 C CA  . GLU A 1 894  ? 117.985 129.816 87.587  1.00 216.20 ? 894  GLU A CA  1 
ATOM 6291 C C   . GLU A 1 894  ? 116.478 129.616 87.692  1.00 205.78 ? 894  GLU A C   1 
ATOM 6292 O O   . GLU A 1 894  ? 115.722 130.083 86.842  1.00 202.29 ? 894  GLU A O   1 
ATOM 6293 C CB  . GLU A 1 894  ? 118.705 128.480 87.373  1.00 236.07 ? 894  GLU A CB  1 
ATOM 6294 C CG  . GLU A 1 894  ? 120.219 128.564 87.505  1.00 252.13 ? 894  GLU A CG  1 
ATOM 6295 C CD  . GLU A 1 894  ? 120.734 128.768 88.922  1.00 255.78 ? 894  GLU A CD  1 
ATOM 6296 O OE1 . GLU A 1 894  ? 121.960 128.926 89.090  1.00 257.04 ? 894  GLU A OE1 1 
ATOM 6297 O OE2 . GLU A 1 894  ? 119.902 128.781 89.854  1.00 249.62 ? 894  GLU A OE2 1 
ATOM 6298 N N   . GLU A 1 895  ? 116.046 128.945 88.766  1.00 201.05 ? 895  GLU A N   1 
ATOM 6299 C CA  . GLU A 1 895  ? 114.623 128.796 89.009  1.00 200.06 ? 895  GLU A CA  1 
ATOM 6300 C C   . GLU A 1 895  ? 113.984 130.167 88.844  1.00 182.97 ? 895  GLU A C   1 
ATOM 6301 O O   . GLU A 1 895  ? 113.029 130.318 88.089  1.00 167.45 ? 895  GLU A O   1 
ATOM 6302 C CB  . GLU A 1 895  ? 114.308 128.257 90.404  1.00 216.72 ? 895  GLU A CB  1 
ATOM 6303 C CG  . GLU A 1 895  ? 114.869 126.878 90.685  1.00 241.41 ? 895  GLU A CG  1 
ATOM 6304 C CD  . GLU A 1 895  ? 114.487 126.365 92.062  1.00 264.92 ? 895  GLU A CD  1 
ATOM 6305 O OE1 . GLU A 1 895  ? 113.272 126.235 92.312  1.00 269.62 ? 895  GLU A OE1 1 
ATOM 6306 O OE2 . GLU A 1 895  ? 115.396 126.119 92.887  1.00 277.40 ? 895  GLU A OE2 1 
ATOM 6307 N N   . LEU A 1 896  ? 114.539 131.165 89.540  1.00 184.05 ? 896  LEU A N   1 
ATOM 6308 C CA  . LEU A 1 896  ? 113.972 132.499 89.481  1.00 190.87 ? 896  LEU A CA  1 
ATOM 6309 C C   . LEU A 1 896  ? 113.807 132.873 88.015  1.00 175.05 ? 896  LEU A C   1 
ATOM 6310 O O   . LEU A 1 896  ? 112.714 133.239 87.597  1.00 157.62 ? 896  LEU A O   1 
ATOM 6311 C CB  . LEU A 1 896  ? 114.849 133.507 90.232  1.00 206.60 ? 896  LEU A CB  1 
ATOM 6312 C CG  . LEU A 1 896  ? 114.397 134.964 90.151  1.00 222.95 ? 896  LEU A CG  1 
ATOM 6313 C CD1 . LEU A 1 896  ? 113.066 135.162 90.858  1.00 223.28 ? 896  LEU A CD1 1 
ATOM 6314 C CD2 . LEU A 1 896  ? 115.450 135.892 90.738  1.00 231.32 ? 896  LEU A CD2 1 
ATOM 6315 N N   . PHE A 1 897  ? 114.879 132.738 87.231  1.00 179.57 ? 897  PHE A N   1 
ATOM 6316 C CA  . PHE A 1 897  ? 114.763 133.074 85.826  1.00 190.46 ? 897  PHE A CA  1 
ATOM 6317 C C   . PHE A 1 897  ? 113.617 132.254 85.245  1.00 175.19 ? 897  PHE A C   1 
ATOM 6318 O O   . PHE A 1 897  ? 112.685 132.822 84.687  1.00 162.00 ? 897  PHE A O   1 
ATOM 6319 C CB  . PHE A 1 897  ? 116.071 132.873 85.057  1.00 211.26 ? 897  PHE A CB  1 
ATOM 6320 C CG  . PHE A 1 897  ? 116.082 133.578 83.724  1.00 239.35 ? 897  PHE A CG  1 
ATOM 6321 C CD1 . PHE A 1 897  ? 116.134 134.962 83.662  1.00 257.29 ? 897  PHE A CD1 1 
ATOM 6322 C CD2 . PHE A 1 897  ? 115.987 132.868 82.536  1.00 254.44 ? 897  PHE A CD2 1 
ATOM 6323 C CE1 . PHE A 1 897  ? 116.122 135.621 82.441  1.00 265.69 ? 897  PHE A CE1 1 
ATOM 6324 C CE2 . PHE A 1 897  ? 115.973 133.528 81.316  1.00 267.43 ? 897  PHE A CE2 1 
ATOM 6325 C CZ  . PHE A 1 897  ? 116.039 134.903 81.271  1.00 269.68 ? 897  PHE A CZ  1 
ATOM 6326 N N   . GLU A 1 898  ? 113.665 130.929 85.440  1.00 172.78 ? 898  GLU A N   1 
ATOM 6327 C CA  . GLU A 1 898  ? 112.634 130.050 84.911  1.00 169.17 ? 898  GLU A CA  1 
ATOM 6328 C C   . GLU A 1 898  ? 111.269 130.561 85.358  1.00 146.48 ? 898  GLU A C   1 
ATOM 6329 O O   . GLU A 1 898  ? 110.382 130.786 84.539  1.00 142.81 ? 898  GLU A O   1 
ATOM 6330 C CB  . GLU A 1 898  ? 112.783 128.601 85.385  1.00 180.81 ? 898  GLU A CB  1 
ATOM 6331 C CG  . GLU A 1 898  ? 114.059 127.910 84.940  1.00 192.86 ? 898  GLU A CG  1 
ATOM 6332 C CD  . GLU A 1 898  ? 114.036 126.406 85.159  1.00 193.12 ? 898  GLU A CD  1 
ATOM 6333 O OE1 . GLU A 1 898  ? 113.784 125.976 86.306  1.00 186.90 ? 898  GLU A OE1 1 
ATOM 6334 O OE2 . GLU A 1 898  ? 114.260 125.665 84.181  1.00 194.01 ? 898  GLU A OE2 1 
ATOM 6335 N N   . TRP A 1 899  ? 111.124 130.726 86.674  1.00 129.25 ? 899  TRP A N   1 
ATOM 6336 C CA  . TRP A 1 899  ? 109.882 131.183 87.266  1.00 120.99 ? 899  TRP A CA  1 
ATOM 6337 C C   . TRP A 1 899  ? 109.474 132.523 86.667  1.00 119.57 ? 899  TRP A C   1 
ATOM 6338 O O   . TRP A 1 899  ? 108.362 132.669 86.166  1.00 109.78 ? 899  TRP A O   1 
ATOM 6339 C CB  . TRP A 1 899  ? 110.024 131.266 88.789  1.00 112.84 ? 899  TRP A CB  1 
ATOM 6340 C CG  . TRP A 1 899  ? 109.983 129.939 89.484  1.00 97.11  ? 899  TRP A CG  1 
ATOM 6341 C CD1 . TRP A 1 899  ? 110.988 129.329 90.180  1.00 89.83  ? 899  TRP A CD1 1 
ATOM 6342 C CD2 . TRP A 1 899  ? 108.844 129.068 89.582  1.00 78.07  ? 899  TRP A CD2 1 
ATOM 6343 N NE1 . TRP A 1 899  ? 110.561 128.135 90.691  1.00 79.25  ? 899  TRP A NE1 1 
ATOM 6344 C CE2 . TRP A 1 899  ? 109.246 127.956 90.348  1.00 75.54  ? 899  TRP A CE2 1 
ATOM 6345 C CE3 . TRP A 1 899  ? 107.532 129.128 89.101  1.00 72.87  ? 899  TRP A CE3 1 
ATOM 6346 C CZ2 . TRP A 1 899  ? 108.376 126.908 90.632  1.00 85.06  ? 899  TRP A CZ2 1 
ATOM 6347 C CZ3 . TRP A 1 899  ? 106.671 128.096 89.390  1.00 74.72  ? 899  TRP A CZ3 1 
ATOM 6348 C CH2 . TRP A 1 899  ? 107.092 127.001 90.146  1.00 86.39  ? 899  TRP A CH2 1 
ATOM 6349 N N   . PHE A 1 900  ? 110.376 133.505 86.731  1.00 130.04 ? 900  PHE A N   1 
ATOM 6350 C CA  . PHE A 1 900  ? 110.020 134.838 86.286  1.00 145.42 ? 900  PHE A CA  1 
ATOM 6351 C C   . PHE A 1 900  ? 109.537 134.754 84.844  1.00 135.63 ? 900  PHE A C   1 
ATOM 6352 O O   . PHE A 1 900  ? 108.485 135.296 84.521  1.00 128.44 ? 900  PHE A O   1 
ATOM 6353 C CB  . PHE A 1 900  ? 111.172 135.834 86.441  1.00 163.51 ? 900  PHE A CB  1 
ATOM 6354 C CG  . PHE A 1 900  ? 110.820 137.238 86.017  1.00 178.94 ? 900  PHE A CG  1 
ATOM 6355 C CD1 . PHE A 1 900  ? 109.792 137.931 86.642  1.00 185.40 ? 900  PHE A CD1 1 
ATOM 6356 C CD2 . PHE A 1 900  ? 111.497 137.855 84.976  1.00 187.73 ? 900  PHE A CD2 1 
ATOM 6357 C CE1 . PHE A 1 900  ? 109.458 139.216 86.244  1.00 190.95 ? 900  PHE A CE1 1 
ATOM 6358 C CE2 . PHE A 1 900  ? 111.170 139.145 84.585  1.00 193.44 ? 900  PHE A CE2 1 
ATOM 6359 C CZ  . PHE A 1 900  ? 110.152 139.822 85.219  1.00 197.53 ? 900  PHE A CZ  1 
ATOM 6360 N N   . GLN A 1 901  ? 110.288 134.053 83.991  1.00 142.92 ? 901  GLN A N   1 
ATOM 6361 C CA  . GLN A 1 901  ? 109.884 133.936 82.602  1.00 159.09 ? 901  GLN A CA  1 
ATOM 6362 C C   . GLN A 1 901  ? 108.523 133.249 82.524  1.00 158.61 ? 901  GLN A C   1 
ATOM 6363 O O   . GLN A 1 901  ? 107.642 133.726 81.817  1.00 162.37 ? 901  GLN A O   1 
ATOM 6364 C CB  . GLN A 1 901  ? 110.921 133.185 81.764  1.00 172.77 ? 901  GLN A CB  1 
ATOM 6365 C CG  . GLN A 1 901  ? 112.288 133.856 81.712  1.00 187.52 ? 901  GLN A CG  1 
ATOM 6366 C CD  . GLN A 1 901  ? 112.237 135.275 81.201  1.00 211.43 ? 901  GLN A CD  1 
ATOM 6367 O OE1 . GLN A 1 901  ? 111.838 135.531 80.067  1.00 219.77 ? 901  GLN A OE1 1 
ATOM 6368 N NE2 . GLN A 1 901  ? 112.643 136.217 82.040  1.00 222.94 ? 901  GLN A NE2 1 
ATOM 6369 N N   . SER A 1 902  ? 108.346 132.142 83.256  1.00 155.62 ? 902  SER A N   1 
ATOM 6370 C CA  . SER A 1 902  ? 107.147 131.331 83.100  1.00 155.21 ? 902  SER A CA  1 
ATOM 6371 C C   . SER A 1 902  ? 105.902 132.121 83.500  1.00 144.21 ? 902  SER A C   1 
ATOM 6372 O O   . SER A 1 902  ? 104.909 132.107 82.779  1.00 138.04 ? 902  SER A O   1 
ATOM 6373 C CB  . SER A 1 902  ? 107.245 130.042 83.867  1.00 163.18 ? 902  SER A CB  1 
ATOM 6374 O OG  . SER A 1 902  ? 107.422 130.291 85.250  1.00 164.85 ? 902  SER A OG  1 
ATOM 6375 N N   . ILE A 1 903  ? 105.965 132.818 84.639  1.00 144.78 ? 903  ILE A N   1 
ATOM 6376 C CA  . ILE A 1 903  ? 104.844 133.633 85.084  1.00 154.05 ? 903  ILE A CA  1 
ATOM 6377 C C   . ILE A 1 903  ? 104.651 134.779 84.089  1.00 163.05 ? 903  ILE A C   1 
ATOM 6378 O O   . ILE A 1 903  ? 103.517 135.108 83.740  1.00 171.05 ? 903  ILE A O   1 
ATOM 6379 C CB  . ILE A 1 903  ? 105.038 134.132 86.534  1.00 160.03 ? 903  ILE A CB  1 
ATOM 6380 C CG1 . ILE A 1 903  ? 105.258 132.968 87.506  1.00 159.02 ? 903  ILE A CG1 1 
ATOM 6381 C CG2 . ILE A 1 903  ? 103.869 134.998 86.982  1.00 163.42 ? 903  ILE A CG2 1 
ATOM 6382 C CD1 . ILE A 1 903  ? 105.474 133.390 88.943  1.00 158.97 ? 903  ILE A CD1 1 
ATOM 6383 N N   . ARG A 1 904  ? 105.762 135.360 83.613  1.00 161.25 ? 904  ARG A N   1 
ATOM 6384 C CA  . ARG A 1 904  ? 105.713 136.496 82.705  1.00 163.10 ? 904  ARG A CA  1 
ATOM 6385 C C   . ARG A 1 904  ? 104.953 136.100 81.443  1.00 171.67 ? 904  ARG A C   1 
ATOM 6386 O O   . ARG A 1 904  ? 104.119 136.858 80.957  1.00 179.86 ? 904  ARG A O   1 
ATOM 6387 C CB  . ARG A 1 904  ? 107.128 136.989 82.380  1.00 166.98 ? 904  ARG A CB  1 
ATOM 6388 C CG  . ARG A 1 904  ? 107.185 138.241 81.517  1.00 179.51 ? 904  ARG A CG  1 
ATOM 6389 C CD  . ARG A 1 904  ? 106.554 139.445 82.192  1.00 190.26 ? 904  ARG A CD  1 
ATOM 6390 N NE  . ARG A 1 904  ? 106.627 140.646 81.371  1.00 205.26 ? 904  ARG A NE  1 
ATOM 6391 C CZ  . ARG A 1 904  ? 107.746 141.298 81.074  1.00 221.27 ? 904  ARG A CZ  1 
ATOM 6392 N NH1 . ARG A 1 904  ? 108.917 140.833 81.473  1.00 216.18 ? 904  ARG A NH1 1 
ATOM 6393 N NH2 . ARG A 1 904  ? 107.689 142.412 80.364  1.00 232.09 ? 904  ARG A NH2 1 
ATOM 6394 N N   . GLU A 1 905  ? 105.227 134.894 80.939  1.00 180.01 ? 905  GLU A N   1 
ATOM 6395 C CA  . GLU A 1 905  ? 104.565 134.389 79.748  1.00 190.41 ? 905  GLU A CA  1 
ATOM 6396 C C   . GLU A 1 905  ? 103.068 134.222 80.012  1.00 178.97 ? 905  GLU A C   1 
ATOM 6397 O O   . GLU A 1 905  ? 102.256 134.540 79.148  1.00 182.61 ? 905  GLU A O   1 
ATOM 6398 C CB  . GLU A 1 905  ? 105.224 133.085 79.293  1.00 208.77 ? 905  GLU A CB  1 
ATOM 6399 C CG  . GLU A 1 905  ? 106.675 133.262 78.868  1.00 222.10 ? 905  GLU A CG  1 
ATOM 6400 C CD  . GLU A 1 905  ? 107.386 131.985 78.452  1.00 237.46 ? 905  GLU A CD  1 
ATOM 6401 O OE1 . GLU A 1 905  ? 106.936 131.354 77.473  1.00 249.42 ? 905  GLU A OE1 1 
ATOM 6402 O OE2 . GLU A 1 905  ? 108.390 131.624 79.100  1.00 241.54 ? 905  GLU A OE2 1 
ATOM 6403 N N   . ILE A 1 906  ? 102.706 133.753 81.214  1.00 172.01 ? 906  ILE A N   1 
ATOM 6404 C CA  . ILE A 1 906  ? 101.306 133.562 81.565  1.00 173.49 ? 906  ILE A CA  1 
ATOM 6405 C C   . ILE A 1 906  ? 100.592 134.911 81.526  1.00 172.34 ? 906  ILE A C   1 
ATOM 6406 O O   . ILE A 1 906  ? 99.466  135.001 81.042  1.00 166.95 ? 906  ILE A O   1 
ATOM 6407 C CB  . ILE A 1 906  ? 101.149 132.875 82.939  1.00 183.50 ? 906  ILE A CB  1 
ATOM 6408 C CG1 . ILE A 1 906  ? 101.891 131.536 83.013  1.00 191.39 ? 906  ILE A CG1 1 
ATOM 6409 C CG2 . ILE A 1 906  ? 99.678  132.715 83.294  1.00 187.99 ? 906  ILE A CG2 1 
ATOM 6410 C CD1 . ILE A 1 906  ? 101.463 130.523 81.973  1.00 200.68 ? 906  ILE A CD1 1 
ATOM 6411 N N   . THR A 1 907  ? 101.259 135.953 82.033  1.00 187.27 ? 907  THR A N   1 
ATOM 6412 C CA  . THR A 1 907  ? 100.691 137.291 82.064  1.00 207.51 ? 907  THR A CA  1 
ATOM 6413 C C   . THR A 1 907  ? 100.535 137.836 80.637  1.00 227.88 ? 907  THR A C   1 
ATOM 6414 O O   . THR A 1 907  ? 99.526  138.476 80.351  1.00 229.46 ? 907  THR A O   1 
ATOM 6415 C CB  . THR A 1 907  ? 101.488 138.179 83.030  1.00 207.47 ? 907  THR A CB  1 
ATOM 6416 O OG1 . THR A 1 907  ? 102.874 138.074 82.716  1.00 207.70 ? 907  THR A OG1 1 
ATOM 6417 C CG2 . THR A 1 907  ? 101.305 137.779 84.478  1.00 208.44 ? 907  THR A CG2 1 
ATOM 6418 N N   . TRP A 1 908  ? 101.496 137.558 79.738  1.00 239.26 ? 908  TRP A N   1 
ATOM 6419 C CA  . TRP A 1 908  ? 101.360 137.900 78.324  1.00 239.91 ? 908  TRP A CA  1 
ATOM 6420 C C   . TRP A 1 908  ? 100.983 136.643 77.525  1.00 231.35 ? 908  TRP A C   1 
ATOM 6421 O O   . TRP A 1 908  ? 101.555 136.452 76.433  1.00 221.55 ? 908  TRP A O   1 
ATOM 6422 C CB  . TRP A 1 908  ? 102.639 138.557 77.773  1.00 248.35 ? 908  TRP A CB  1 
ATOM 6423 C CG  . TRP A 1 908  ? 102.849 140.000 78.134  1.00 263.40 ? 908  TRP A CG  1 
ATOM 6424 C CD1 . TRP A 1 908  ? 102.868 141.058 77.269  1.00 278.54 ? 908  TRP A CD1 1 
ATOM 6425 C CD2 . TRP A 1 908  ? 103.125 140.552 79.436  1.00 265.86 ? 908  TRP A CD2 1 
ATOM 6426 N NE1 . TRP A 1 908  ? 103.111 142.225 77.943  1.00 280.99 ? 908  TRP A NE1 1 
ATOM 6427 C CE2 . TRP A 1 908  ? 103.275 141.947 79.273  1.00 274.88 ? 908  TRP A CE2 1 
ATOM 6428 C CE3 . TRP A 1 908  ? 103.251 140.013 80.721  1.00 263.88 ? 908  TRP A CE3 1 
ATOM 6429 C CZ2 . TRP A 1 908  ? 103.543 142.799 80.345  1.00 274.89 ? 908  TRP A CZ2 1 
ATOM 6430 C CZ3 . TRP A 1 908  ? 103.511 140.855 81.781  1.00 269.33 ? 908  TRP A CZ3 1 
ATOM 6431 C CH2 . TRP A 1 908  ? 103.657 142.229 81.593  1.00 274.24 ? 908  TRP A CH2 1 
ATOM 6432 N N   . GLN A 1 924  ? 111.653 108.662 64.200  1.00 136.22 ? 924  GLN A N   1 
ATOM 6433 C CA  . GLN A 1 924  ? 111.255 108.400 65.611  1.00 138.32 ? 924  GLN A CA  1 
ATOM 6434 C C   . GLN A 1 924  ? 112.463 107.881 66.388  1.00 147.42 ? 924  GLN A C   1 
ATOM 6435 O O   . GLN A 1 924  ? 113.348 107.246 65.817  1.00 159.26 ? 924  GLN A O   1 
ATOM 6436 C CB  . GLN A 1 924  ? 110.095 107.403 65.680  1.00 133.10 ? 924  GLN A CB  1 
ATOM 6437 C CG  . GLN A 1 924  ? 110.448 106.002 65.198  1.00 135.94 ? 924  GLN A CG  1 
ATOM 6438 C CD  . GLN A 1 924  ? 109.236 105.113 65.058  1.00 139.38 ? 924  GLN A CD  1 
ATOM 6439 O OE1 . GLN A 1 924  ? 109.025 104.481 64.025  1.00 141.47 ? 924  GLN A OE1 1 
ATOM 6440 N NE2 . GLN A 1 924  ? 108.436 105.043 66.110  1.00 142.26 ? 924  GLN A NE2 1 
ATOM 6441 N N   . SER A 1 925  ? 112.477 108.135 67.705  1.00 132.13 ? 925  SER A N   1 
ATOM 6442 C CA  . SER A 1 925  ? 113.578 107.714 68.561  1.00 115.92 ? 925  SER A CA  1 
ATOM 6443 C C   . SER A 1 925  ? 113.461 106.219 68.855  1.00 105.68 ? 925  SER A C   1 
ATOM 6444 O O   . SER A 1 925  ? 112.739 105.518 68.152  1.00 110.91 ? 925  SER A O   1 
ATOM 6445 C CB  . SER A 1 925  ? 113.628 108.544 69.811  1.00 113.52 ? 925  SER A CB  1 
ATOM 6446 O OG  . SER A 1 925  ? 113.864 109.906 69.489  1.00 115.68 ? 925  SER A OG  1 
ATOM 6447 N N   . ILE A 1 926  ? 114.196 105.740 69.869  1.00 95.34  ? 926  ILE A N   1 
ATOM 6448 C CA  . ILE A 1 926  ? 114.289 104.327 70.215  1.00 95.30  ? 926  ILE A CA  1 
ATOM 6449 C C   . ILE A 1 926  ? 115.402 103.703 69.377  1.00 93.32  ? 926  ILE A C   1 
ATOM 6450 O O   . ILE A 1 926  ? 115.193 103.418 68.197  1.00 101.24 ? 926  ILE A O   1 
ATOM 6451 C CB  . ILE A 1 926  ? 112.954 103.566 70.030  1.00 96.30  ? 926  ILE A CB  1 
ATOM 6452 C CG1 . ILE A 1 926  ? 111.767 104.242 70.724  1.00 102.88 ? 926  ILE A CG1 1 
ATOM 6453 C CG2 . ILE A 1 926  ? 113.102 102.115 70.473  1.00 99.06  ? 926  ILE A CG2 1 
ATOM 6454 C CD1 . ILE A 1 926  ? 111.948 104.431 72.216  1.00 112.66 ? 926  ILE A CD1 1 
ATOM 6455 N N   . ALA A 1 927  ? 116.576 103.492 69.988  1.00 93.14  ? 927  ALA A N   1 
ATOM 6456 C CA  . ALA A 1 927  ? 117.697 102.861 69.308  1.00 102.69 ? 927  ALA A CA  1 
ATOM 6457 C C   . ALA A 1 927  ? 117.312 101.424 68.964  1.00 120.50 ? 927  ALA A C   1 
ATOM 6458 O O   . ALA A 1 927  ? 116.568 100.792 69.705  1.00 122.23 ? 927  ALA A O   1 
ATOM 6459 C CB  . ALA A 1 927  ? 118.937 102.918 70.166  1.00 98.74  ? 927  ALA A CB  1 
ATOM 6460 N N   . ILE A 1 928  ? 117.809 100.920 67.828  1.00 128.67 ? 928  ILE A N   1 
ATOM 6461 C CA  . ILE A 1 928  ? 117.359 99.641  67.293  1.00 124.61 ? 928  ILE A CA  1 
ATOM 6462 C C   . ILE A 1 928  ? 117.579 98.527  68.317  1.00 118.65 ? 928  ILE A C   1 
ATOM 6463 O O   . ILE A 1 928  ? 116.716 97.672  68.481  1.00 112.12 ? 928  ILE A O   1 
ATOM 6464 C CB  . ILE A 1 928  ? 118.035 99.324  65.940  1.00 131.75 ? 928  ILE A CB  1 
ATOM 6465 C CG1 . ILE A 1 928  ? 117.485 98.040  65.310  1.00 133.21 ? 928  ILE A CG1 1 
ATOM 6466 C CG2 . ILE A 1 928  ? 119.553 99.271  66.074  1.00 137.36 ? 928  ILE A CG2 1 
ATOM 6467 C CD1 . ILE A 1 928  ? 115.998 98.062  65.041  1.00 132.13 ? 928  ILE A CD1 1 
ATOM 6468 N N   . GLU A 1 929  ? 118.722 98.542  69.014  1.00 122.09 ? 929  GLU A N   1 
ATOM 6469 C CA  . GLU A 1 929  ? 119.095 97.433  69.877  1.00 128.61 ? 929  GLU A CA  1 
ATOM 6470 C C   . GLU A 1 929  ? 118.025 97.223  70.951  1.00 115.31 ? 929  GLU A C   1 
ATOM 6471 O O   . GLU A 1 929  ? 117.605 96.092  71.200  1.00 115.23 ? 929  GLU A O   1 
ATOM 6472 C CB  . GLU A 1 929  ? 120.478 97.677  70.485  1.00 143.35 ? 929  GLU A CB  1 
ATOM 6473 C CG  . GLU A 1 929  ? 120.991 96.506  71.306  1.00 167.17 ? 929  GLU A CG  1 
ATOM 6474 C CD  . GLU A 1 929  ? 122.382 96.704  71.886  1.00 189.52 ? 929  GLU A CD  1 
ATOM 6475 O OE1 . GLU A 1 929  ? 122.510 96.664  73.128  1.00 192.70 ? 929  GLU A OE1 1 
ATOM 6476 O OE2 . GLU A 1 929  ? 123.331 96.902  71.099  1.00 203.20 ? 929  GLU A OE2 1 
ATOM 6477 N N   . LEU A 1 930  ? 117.596 98.316  71.593  1.00 106.36 ? 930  LEU A N   1 
ATOM 6478 C CA  . LEU A 1 930  ? 116.569 98.244  72.618  1.00 101.23 ? 930  LEU A CA  1 
ATOM 6479 C C   . LEU A 1 930  ? 115.337 97.615  71.979  1.00 91.17  ? 930  LEU A C   1 
ATOM 6480 O O   . LEU A 1 930  ? 114.705 96.738  72.559  1.00 97.71  ? 930  LEU A O   1 
ATOM 6481 C CB  . LEU A 1 930  ? 116.290 99.653  73.164  1.00 110.13 ? 930  LEU A CB  1 
ATOM 6482 C CG  . LEU A 1 930  ? 115.487 99.763  74.463  1.00 122.70 ? 930  LEU A CG  1 
ATOM 6483 C CD1 . LEU A 1 930  ? 114.263 98.852  74.474  1.00 127.01 ? 930  LEU A CD1 1 
ATOM 6484 C CD2 . LEU A 1 930  ? 116.362 99.496  75.678  1.00 130.30 ? 930  LEU A CD2 1 
ATOM 6485 N N   . SER A 1 931  ? 115.038 98.038  70.750  1.00 91.99  ? 931  SER A N   1 
ATOM 6486 C CA  . SER A 1 931  ? 113.855 97.579  70.049  1.00 114.28 ? 931  SER A CA  1 
ATOM 6487 C C   . SER A 1 931  ? 113.879 96.061  69.872  1.00 121.48 ? 931  SER A C   1 
ATOM 6488 O O   . SER A 1 931  ? 112.839 95.416  69.999  1.00 127.77 ? 931  SER A O   1 
ATOM 6489 C CB  . SER A 1 931  ? 113.700 98.288  68.729  1.00 129.32 ? 931  SER A CB  1 
ATOM 6490 O OG  . SER A 1 931  ? 112.529 97.859  68.049  1.00 137.31 ? 931  SER A OG  1 
ATOM 6491 N N   . ASP A 1 932  ? 115.058 95.494  69.581  1.00 125.60 ? 932  ASP A N   1 
ATOM 6492 C CA  . ASP A 1 932  ? 115.172 94.057  69.379  1.00 140.62 ? 932  ASP A CA  1 
ATOM 6493 C C   . ASP A 1 932  ? 114.748 93.312  70.646  1.00 124.63 ? 932  ASP A C   1 
ATOM 6494 O O   . ASP A 1 932  ? 114.076 92.279  70.561  1.00 123.99 ? 932  ASP A O   1 
ATOM 6495 C CB  . ASP A 1 932  ? 116.585 93.638  68.956  1.00 165.68 ? 932  ASP A CB  1 
ATOM 6496 C CG  . ASP A 1 932  ? 117.002 94.134  67.579  1.00 187.83 ? 932  ASP A CG  1 
ATOM 6497 O OD1 . ASP A 1 932  ? 117.089 95.367  67.402  1.00 198.11 ? 932  ASP A OD1 1 
ATOM 6498 O OD2 . ASP A 1 932  ? 117.247 93.283  66.697  1.00 201.25 ? 932  ASP A OD2 1 
ATOM 6499 N N   . LEU A 1 933  ? 115.129 93.844  71.818  1.00 99.87  ? 933  LEU A N   1 
ATOM 6500 C CA  . LEU A 1 933  ? 114.863 93.163  73.072  1.00 79.03  ? 933  LEU A CA  1 
ATOM 6501 C C   . LEU A 1 933  ? 113.368 92.923  73.230  1.00 66.24  ? 933  LEU A C   1 
ATOM 6502 O O   . LEU A 1 933  ? 112.980 91.874  73.718  1.00 75.05  ? 933  LEU A O   1 
ATOM 6503 C CB  . LEU A 1 933  ? 115.435 93.959  74.250  1.00 74.41  ? 933  LEU A CB  1 
ATOM 6504 C CG  . LEU A 1 933  ? 116.954 94.135  74.234  1.00 83.76  ? 933  LEU A CG  1 
ATOM 6505 C CD1 . LEU A 1 933  ? 117.464 94.619  75.584  1.00 87.01  ? 933  LEU A CD1 1 
ATOM 6506 C CD2 . LEU A 1 933  ? 117.659 92.847  73.827  1.00 85.60  ? 933  LEU A CD2 1 
ATOM 6507 N N   . VAL A 1 934  ? 112.535 93.870  72.799  1.00 58.41  ? 934  VAL A N   1 
ATOM 6508 C CA  . VAL A 1 934  ? 111.123 93.862  73.146  1.00 62.73  ? 934  VAL A CA  1 
ATOM 6509 C C   . VAL A 1 934  ? 110.371 92.789  72.366  1.00 58.46  ? 934  VAL A C   1 
ATOM 6510 O O   . VAL A 1 934  ? 109.559 93.108  71.504  1.00 66.08  ? 934  VAL A O   1 
ATOM 6511 C CB  . VAL A 1 934  ? 110.513 95.259  72.918  1.00 74.52  ? 934  VAL A CB  1 
ATOM 6512 C CG1 . VAL A 1 934  ? 109.014 95.301  73.211  1.00 74.78  ? 934  VAL A CG1 1 
ATOM 6513 C CG2 . VAL A 1 934  ? 111.255 96.317  73.730  1.00 80.66  ? 934  VAL A CG2 1 
ATOM 6514 N N   . VAL A 1 935  ? 110.571 91.519  72.720  1.00 66.77  ? 935  VAL A N   1 
ATOM 6515 C CA  . VAL A 1 935  ? 109.993 90.422  71.956  1.00 84.66  ? 935  VAL A CA  1 
ATOM 6516 C C   . VAL A 1 935  ? 108.505 90.262  72.252  1.00 77.63  ? 935  VAL A C   1 
ATOM 6517 O O   . VAL A 1 935  ? 107.733 89.969  71.340  1.00 74.98  ? 935  VAL A O   1 
ATOM 6518 C CB  . VAL A 1 935  ? 110.753 89.105  72.202  1.00 106.51 ? 935  VAL A CB  1 
ATOM 6519 C CG1 . VAL A 1 935  ? 110.012 87.894  71.648  1.00 109.41 ? 935  VAL A CG1 1 
ATOM 6520 C CG2 . VAL A 1 935  ? 112.164 89.191  71.638  1.00 115.30 ? 935  VAL A CG2 1 
ATOM 6521 N N   . TYR A 1 936  ? 108.110 90.388  73.523  1.00 82.57  ? 936  TYR A N   1 
ATOM 6522 C CA  . TYR A 1 936  ? 106.710 90.218  73.904  1.00 97.40  ? 936  TYR A CA  1 
ATOM 6523 C C   . TYR A 1 936  ? 106.293 91.444  74.717  1.00 109.27 ? 936  TYR A C   1 
ATOM 6524 O O   . TYR A 1 936  ? 107.151 92.137  75.259  1.00 109.58 ? 936  TYR A O   1 
ATOM 6525 C CB  . TYR A 1 936  ? 106.442 88.936  74.712  1.00 99.38  ? 936  TYR A CB  1 
ATOM 6526 C CG  . TYR A 1 936  ? 106.512 87.609  73.989  1.00 102.65 ? 936  TYR A CG  1 
ATOM 6527 C CD1 . TYR A 1 936  ? 105.783 87.360  72.839  1.00 118.87 ? 936  TYR A CD1 1 
ATOM 6528 C CD2 . TYR A 1 936  ? 107.265 86.565  74.498  1.00 111.96 ? 936  TYR A CD2 1 
ATOM 6529 C CE1 . TYR A 1 936  ? 105.864 86.145  72.179  1.00 139.23 ? 936  TYR A CE1 1 
ATOM 6530 C CE2 . TYR A 1 936  ? 107.362 85.343  73.851  1.00 127.23 ? 936  TYR A CE2 1 
ATOM 6531 C CZ  . TYR A 1 936  ? 106.648 85.125  72.688  1.00 141.03 ? 936  TYR A CZ  1 
ATOM 6532 O OH  . TYR A 1 936  ? 106.712 83.903  72.054  1.00 149.20 ? 936  TYR A OH  1 
ATOM 6533 N N   . CYS A 1 937  ? 104.977 91.689  74.799  1.00 113.37 ? 937  CYS A N   1 
ATOM 6534 C CA  . CYS A 1 937  ? 104.443 92.934  75.331  1.00 120.28 ? 937  CYS A CA  1 
ATOM 6535 C C   . CYS A 1 937  ? 104.949 94.104  74.490  1.00 116.62 ? 937  CYS A C   1 
ATOM 6536 O O   . CYS A 1 937  ? 106.093 94.516  74.645  1.00 111.92 ? 937  CYS A O   1 
ATOM 6537 C CB  . CYS A 1 937  ? 104.845 93.158  76.786  1.00 130.43 ? 937  CYS A CB  1 
ATOM 6538 S SG  . CYS A 1 937  ? 104.331 91.840  77.917  1.00 170.96 ? 937  CYS A SG  1 
ATOM 6539 N N   . LYS A 1 938  ? 104.090 94.632  73.608  1.00 109.11 ? 938  LYS A N   1 
ATOM 6540 C CA  . LYS A 1 938  ? 104.475 95.684  72.681  1.00 103.29 ? 938  LYS A CA  1 
ATOM 6541 C C   . LYS A 1 938  ? 103.620 96.919  72.946  1.00 88.78  ? 938  LYS A C   1 
ATOM 6542 O O   . LYS A 1 938  ? 102.395 96.825  72.936  1.00 80.70  ? 938  LYS A O   1 
ATOM 6543 C CB  . LYS A 1 938  ? 104.292 95.181  71.248  1.00 117.19 ? 938  LYS A CB  1 
ATOM 6544 C CG  . LYS A 1 938  ? 104.658 96.165  70.143  1.00 136.05 ? 938  LYS A CG  1 
ATOM 6545 C CD  . LYS A 1 938  ? 104.380 95.644  68.740  1.00 139.58 ? 938  LYS A CD  1 
ATOM 6546 C CE  . LYS A 1 938  ? 105.011 94.298  68.440  1.00 141.78 ? 938  LYS A CE  1 
ATOM 6547 N NZ  . LYS A 1 938  ? 106.488 94.305  68.594  1.00 140.20 ? 938  LYS A NZ  1 
ATOM 6548 N N   . PRO A 1 939  ? 104.215 98.105  73.219  1.00 83.44  ? 939  PRO A N   1 
ATOM 6549 C CA  . PRO A 1 939  ? 103.424 99.328  73.306  1.00 88.29  ? 939  PRO A CA  1 
ATOM 6550 C C   . PRO A 1 939  ? 102.758 99.461  71.946  1.00 95.91  ? 939  PRO A C   1 
ATOM 6551 O O   . PRO A 1 939  ? 103.468 99.509  70.944  1.00 108.51 ? 939  PRO A O   1 
ATOM 6552 C CB  . PRO A 1 939  ? 104.470 100.414 73.596  1.00 86.73  ? 939  PRO A CB  1 
ATOM 6553 C CG  . PRO A 1 939  ? 105.592 99.642  74.242  1.00 81.36  ? 939  PRO A CG  1 
ATOM 6554 C CD  . PRO A 1 939  ? 105.648 98.357  73.444  1.00 76.69  ? 939  PRO A CD  1 
ATOM 6555 N N   . THR A 1 940  ? 101.420 99.429  71.916  1.00 100.61 ? 940  THR A N   1 
ATOM 6556 C CA  . THR A 1 940  ? 100.688 99.421  70.660  1.00 113.05 ? 940  THR A CA  1 
ATOM 6557 C C   . THR A 1 940  ? 100.466 100.844 70.168  1.00 143.73 ? 940  THR A C   1 
ATOM 6558 O O   . THR A 1 940  ? 99.975  101.696 70.901  1.00 155.02 ? 940  THR A O   1 
ATOM 6559 C CB  . THR A 1 940  ? 99.299  98.789  70.784  1.00 108.57 ? 940  THR A CB  1 
ATOM 6560 O OG1 . THR A 1 940  ? 98.501  99.662  71.579  1.00 108.95 ? 940  THR A OG1 1 
ATOM 6561 C CG2 . THR A 1 940  ? 99.319  97.414  71.406  1.00 117.53 ? 940  THR A CG2 1 
ATOM 6562 N N   . SER A 1 941  ? 100.819 101.091 68.913  1.00 170.78 ? 941  SER A N   1 
ATOM 6563 C CA  . SER A 1 941  ? 100.340 102.282 68.250  1.00 190.27 ? 941  SER A CA  1 
ATOM 6564 C C   . SER A 1 941  ? 99.001  101.906 67.640  1.00 195.71 ? 941  SER A C   1 
ATOM 6565 O O   . SER A 1 941  ? 98.972  101.158 66.670  1.00 185.67 ? 941  SER A O   1 
ATOM 6566 C CB  . SER A 1 941  ? 101.325 102.769 67.237  1.00 202.99 ? 941  SER A CB  1 
ATOM 6567 O OG  . SER A 1 941  ? 102.570 103.065 67.851  1.00 206.40 ? 941  SER A OG  1 
ATOM 6568 N N   . LYS A 1 942  ? 97.917  102.334 68.290  1.00 208.01 ? 942  LYS A N   1 
ATOM 6569 C CA  . LYS A 1 942  ? 96.577  101.942 67.894  1.00 219.56 ? 942  LYS A CA  1 
ATOM 6570 C C   . LYS A 1 942  ? 95.601  102.960 68.470  1.00 230.21 ? 942  LYS A C   1 
ATOM 6571 O O   . LYS A 1 942  ? 95.928  103.665 69.421  1.00 231.21 ? 942  LYS A O   1 
ATOM 6572 C CB  . LYS A 1 942  ? 96.260  100.524 68.387  1.00 219.94 ? 942  LYS A CB  1 
ATOM 6573 C CG  . LYS A 1 942  ? 94.958  99.920  67.875  1.00 214.74 ? 942  LYS A CG  1 
ATOM 6574 C CD  . LYS A 1 942  ? 94.900  99.859  66.362  1.00 208.45 ? 942  LYS A CD  1 
ATOM 6575 C CE  . LYS A 1 942  ? 93.632  99.227  65.827  1.00 211.10 ? 942  LYS A CE  1 
ATOM 6576 N NZ  . LYS A 1 942  ? 93.428  97.855  66.350  1.00 212.52 ? 942  LYS A NZ  1 
ATOM 6577 N N   . THR A 1 943  ? 94.411  103.037 67.875  1.00 239.39 ? 943  THR A N   1 
ATOM 6578 C CA  . THR A 1 943  ? 93.373  103.916 68.378  1.00 248.92 ? 943  THR A CA  1 
ATOM 6579 C C   . THR A 1 943  ? 92.770  103.269 69.625  1.00 243.97 ? 943  THR A C   1 
ATOM 6580 O O   . THR A 1 943  ? 92.031  102.295 69.519  1.00 235.04 ? 943  THR A O   1 
ATOM 6581 C CB  . THR A 1 943  ? 92.402  104.223 67.235  1.00 258.91 ? 943  THR A CB  1 
ATOM 6582 O OG1 . THR A 1 943  ? 91.857  102.979 66.796  1.00 262.32 ? 943  THR A OG1 1 
ATOM 6583 C CG2 . THR A 1 943  ? 93.058  104.934 66.073  1.00 261.18 ? 943  THR A CG2 1 
ATOM 6584 N N   . LYS A 1 944  ? 93.119  103.805 70.806  1.00 238.04 ? 944  LYS A N   1 
ATOM 6585 C CA  . LYS A 1 944  ? 92.655  103.276 72.083  1.00 228.99 ? 944  LYS A CA  1 
ATOM 6586 C C   . LYS A 1 944  ? 91.164  102.953 72.004  1.00 217.62 ? 944  LYS A C   1 
ATOM 6587 O O   . LYS A 1 944  ? 90.622  102.284 72.880  1.00 210.87 ? 944  LYS A O   1 
ATOM 6588 C CB  . LYS A 1 944  ? 92.937  104.268 73.220  1.00 233.02 ? 944  LYS A CB  1 
ATOM 6589 C CG  . LYS A 1 944  ? 94.407  104.596 73.457  1.00 239.70 ? 944  LYS A CG  1 
ATOM 6590 C CD  . LYS A 1 944  ? 95.270  103.385 73.750  1.00 240.68 ? 944  LYS A CD  1 
ATOM 6591 C CE  . LYS A 1 944  ? 96.721  103.738 73.998  1.00 245.42 ? 944  LYS A CE  1 
ATOM 6592 N NZ  . LYS A 1 944  ? 97.351  104.361 72.809  1.00 245.76 ? 944  LYS A NZ  1 
ATOM 6593 N N   . ASP A 1 945  ? 90.516  103.449 70.944  1.00 216.84 ? 945  ASP A N   1 
ATOM 6594 C CA  . ASP A 1 945  ? 89.129  103.138 70.648  1.00 220.73 ? 945  ASP A CA  1 
ATOM 6595 C C   . ASP A 1 945  ? 88.961  101.701 70.159  1.00 198.27 ? 945  ASP A C   1 
ATOM 6596 O O   . ASP A 1 945  ? 88.033  101.022 70.587  1.00 199.32 ? 945  ASP A O   1 
ATOM 6597 C CB  . ASP A 1 945  ? 88.563  104.108 69.609  1.00 247.10 ? 945  ASP A CB  1 
ATOM 6598 C CG  . ASP A 1 945  ? 89.425  104.251 68.367  1.00 262.92 ? 945  ASP A CG  1 
ATOM 6599 O OD1 . ASP A 1 945  ? 89.606  103.242 67.655  1.00 270.64 ? 945  ASP A OD1 1 
ATOM 6600 O OD2 . ASP A 1 945  ? 89.919  105.370 68.129  1.00 267.78 ? 945  ASP A OD2 1 
ATOM 6601 N N   . ASN A 1 946  ? 89.811  101.251 69.229  1.00 186.04 ? 946  ASN A N   1 
ATOM 6602 C CA  . ASN A 1 946  ? 89.566  99.995  68.538  1.00 191.09 ? 946  ASN A CA  1 
ATOM 6603 C C   . ASN A 1 946  ? 89.980  98.814  69.412  1.00 177.23 ? 946  ASN A C   1 
ATOM 6604 O O   . ASN A 1 946  ? 90.932  98.106  69.098  1.00 177.57 ? 946  ASN A O   1 
ATOM 6605 C CB  . ASN A 1 946  ? 90.277  99.935  67.182  1.00 214.68 ? 946  ASN A CB  1 
ATOM 6606 C CG  . ASN A 1 946  ? 89.944  98.690  66.384  1.00 240.82 ? 946  ASN A CG  1 
ATOM 6607 O OD1 . ASN A 1 946  ? 89.167  97.845  66.826  1.00 246.23 ? 946  ASN A OD1 1 
ATOM 6608 N ND2 . ASN A 1 946  ? 90.527  98.565  65.202  1.00 253.79 ? 946  ASN A ND2 1 
ATOM 6609 N N   . LEU A 1 947  ? 89.233  98.559  70.488  1.00 171.02 ? 947  LEU A N   1 
ATOM 6610 C CA  . LEU A 1 947  ? 89.305  97.248  71.107  1.00 162.19 ? 947  LEU A CA  1 
ATOM 6611 C C   . LEU A 1 947  ? 88.809  96.264  70.056  1.00 165.81 ? 947  LEU A C   1 
ATOM 6612 O O   . LEU A 1 947  ? 87.869  96.591  69.340  1.00 167.91 ? 947  LEU A O   1 
ATOM 6613 C CB  . LEU A 1 947  ? 88.453  97.207  72.378  1.00 164.94 ? 947  LEU A CB  1 
ATOM 6614 C CG  . LEU A 1 947  ? 88.765  98.279  73.425  1.00 167.89 ? 947  LEU A CG  1 
ATOM 6615 C CD1 . LEU A 1 947  ? 88.187  97.911  74.780  1.00 172.02 ? 947  LEU A CD1 1 
ATOM 6616 C CD2 . LEU A 1 947  ? 90.257  98.529  73.550  1.00 159.49 ? 947  LEU A CD2 1 
ATOM 6617 N N   . GLU A 1 948  ? 89.506  95.126  69.924  1.00 177.86 ? 948  GLU A N   1 
ATOM 6618 C CA  . GLU A 1 948  ? 89.221  94.061  68.966  1.00 190.60 ? 948  GLU A CA  1 
ATOM 6619 C C   . GLU A 1 948  ? 90.490  93.763  68.166  1.00 190.42 ? 948  GLU A C   1 
ATOM 6620 O O   . GLU A 1 948  ? 91.550  94.321  68.450  1.00 188.56 ? 948  GLU A O   1 
ATOM 6621 C CB  . GLU A 1 948  ? 88.035  94.365  68.038  1.00 197.92 ? 948  GLU A CB  1 
ATOM 6622 C CG  . GLU A 1 948  ? 86.661  94.210  68.682  1.00 211.60 ? 948  GLU A CG  1 
ATOM 6623 C CD  . GLU A 1 948  ? 86.370  92.852  69.298  1.00 225.86 ? 948  GLU A CD  1 
ATOM 6624 O OE1 . GLU A 1 948  ? 87.025  92.513  70.305  1.00 231.19 ? 948  GLU A OE1 1 
ATOM 6625 O OE2 . GLU A 1 948  ? 85.480  92.140  68.779  1.00 232.03 ? 948  GLU A OE2 1 
ATOM 6626 N N   . ASN A 1 949  ? 90.375  92.836  67.201  1.00 184.15 ? 949  ASN A N   1 
ATOM 6627 C CA  . ASN A 1 949  ? 91.502  92.347  66.419  1.00 176.67 ? 949  ASN A CA  1 
ATOM 6628 C C   . ASN A 1 949  ? 92.761  92.363  67.284  1.00 147.27 ? 949  ASN A C   1 
ATOM 6629 O O   . ASN A 1 949  ? 93.793  92.908  66.895  1.00 142.98 ? 949  ASN A O   1 
ATOM 6630 C CB  . ASN A 1 949  ? 91.651  93.110  65.099  1.00 193.95 ? 949  ASN A CB  1 
ATOM 6631 C CG  . ASN A 1 949  ? 90.629  92.690  64.063  1.00 213.41 ? 949  ASN A CG  1 
ATOM 6632 O OD1 . ASN A 1 949  ? 89.425  92.813  64.281  1.00 221.50 ? 949  ASN A OD1 1 
ATOM 6633 N ND2 . ASN A 1 949  ? 91.097  92.184  62.934  1.00 224.29 ? 949  ASN A ND2 1 
ATOM 6634 N N   . PRO A 1 950  ? 92.713  91.740  68.484  1.00 119.57 ? 950  PRO A N   1 
ATOM 6635 C CA  . PRO A 1 950  ? 93.859  91.715  69.390  1.00 103.68 ? 950  PRO A CA  1 
ATOM 6636 C C   . PRO A 1 950  ? 95.062  90.993  68.799  1.00 98.47  ? 950  PRO A C   1 
ATOM 6637 O O   . PRO A 1 950  ? 94.902  89.973  68.133  1.00 100.30 ? 950  PRO A O   1 
ATOM 6638 C CB  . PRO A 1 950  ? 93.366  90.886  70.584  1.00 114.04 ? 950  PRO A CB  1 
ATOM 6639 C CG  . PRO A 1 950  ? 92.244  90.051  70.004  1.00 121.41 ? 950  PRO A CG  1 
ATOM 6640 C CD  . PRO A 1 950  ? 91.571  90.974  69.013  1.00 122.58 ? 950  PRO A CD  1 
ATOM 6641 N N   . ASP A 1 951  ? 96.260  91.520  69.073  1.00 113.89 ? 951  ASP A N   1 
ATOM 6642 C CA  . ASP A 1 951  ? 97.504  90.893  68.660  1.00 132.21 ? 951  ASP A CA  1 
ATOM 6643 C C   . ASP A 1 951  ? 98.251  90.447  69.913  1.00 119.58 ? 951  ASP A C   1 
ATOM 6644 O O   . ASP A 1 951  ? 98.611  91.277  70.738  1.00 110.92 ? 951  ASP A O   1 
ATOM 6645 C CB  . ASP A 1 951  ? 98.349  91.854  67.818  1.00 154.05 ? 951  ASP A CB  1 
ATOM 6646 C CG  . ASP A 1 951  ? 99.444  91.175  67.014  1.00 174.72 ? 951  ASP A CG  1 
ATOM 6647 O OD1 . ASP A 1 951  ? 99.454  89.930  66.968  1.00 184.73 ? 951  ASP A OD1 1 
ATOM 6648 O OD2 . ASP A 1 951  ? 100.284 91.899  66.442  1.00 188.94 ? 951  ASP A OD2 1 
ATOM 6649 N N   . PHE A 1 952  ? 98.454  89.133  70.055  1.00 112.87 ? 952  PHE A N   1 
ATOM 6650 C CA  . PHE A 1 952  ? 99.025  88.553  71.262  1.00 105.34 ? 952  PHE A CA  1 
ATOM 6651 C C   . PHE A 1 952  ? 100.186 89.399  71.777  1.00 87.66  ? 952  PHE A C   1 
ATOM 6652 O O   . PHE A 1 952  ? 100.185 89.787  72.943  1.00 99.05  ? 952  PHE A O   1 
ATOM 6653 C CB  . PHE A 1 952  ? 99.452  87.098  71.040  1.00 113.52 ? 952  PHE A CB  1 
ATOM 6654 C CG  . PHE A 1 952  ? 100.580 86.890  70.062  1.00 132.95 ? 952  PHE A CG  1 
ATOM 6655 C CD1 . PHE A 1 952  ? 100.426 87.230  68.726  1.00 165.09 ? 952  PHE A CD1 1 
ATOM 6656 C CD2 . PHE A 1 952  ? 101.788 86.347  70.466  1.00 131.95 ? 952  PHE A CD2 1 
ATOM 6657 C CE1 . PHE A 1 952  ? 101.455 87.040  67.817  1.00 168.43 ? 952  PHE A CE1 1 
ATOM 6658 C CE2 . PHE A 1 952  ? 102.817 86.164  69.556  1.00 143.77 ? 952  PHE A CE2 1 
ATOM 6659 C CZ  . PHE A 1 952  ? 102.651 86.513  68.237  1.00 156.71 ? 952  PHE A CZ  1 
ATOM 6660 N N   . ARG A 1 953  ? 101.163 89.694  70.917  1.00 78.61  ? 953  ARG A N   1 
ATOM 6661 C CA  . ARG A 1 953  ? 102.406 90.295  71.373  1.00 95.57  ? 953  ARG A CA  1 
ATOM 6662 C C   . ARG A 1 953  ? 102.188 91.716  71.907  1.00 100.13 ? 953  ARG A C   1 
ATOM 6663 O O   . ARG A 1 953  ? 102.983 92.188  72.715  1.00 105.37 ? 953  ARG A O   1 
ATOM 6664 C CB  . ARG A 1 953  ? 103.454 90.246  70.256  1.00 116.23 ? 953  ARG A CB  1 
ATOM 6665 C CG  . ARG A 1 953  ? 103.035 90.926  68.960  1.00 143.42 ? 953  ARG A CG  1 
ATOM 6666 C CD  . ARG A 1 953  ? 104.066 90.751  67.855  1.00 153.76 ? 953  ARG A CD  1 
ATOM 6667 N NE  . ARG A 1 953  ? 104.382 89.354  67.581  1.00 152.95 ? 953  ARG A NE  1 
ATOM 6668 C CZ  . ARG A 1 953  ? 105.558 88.776  67.809  1.00 160.06 ? 953  ARG A CZ  1 
ATOM 6669 N NH1 . ARG A 1 953  ? 106.578 89.483  68.264  1.00 165.94 ? 953  ARG A NH1 1 
ATOM 6670 N NH2 . ARG A 1 953  ? 105.715 87.486  67.570  1.00 160.11 ? 953  ARG A NH2 1 
ATOM 6671 N N   . GLU A 1 954  ? 101.108 92.388  71.495  1.00 99.08  ? 954  GLU A N   1 
ATOM 6672 C CA  . GLU A 1 954  ? 100.878 93.796  71.800  1.00 106.99 ? 954  GLU A CA  1 
ATOM 6673 C C   . GLU A 1 954  ? 100.173 94.007  73.143  1.00 103.42 ? 954  GLU A C   1 
ATOM 6674 O O   . GLU A 1 954  ? 99.220  93.292  73.446  1.00 117.45 ? 954  GLU A O   1 
ATOM 6675 C CB  . GLU A 1 954  ? 99.993  94.377  70.702  1.00 131.51 ? 954  GLU A CB  1 
ATOM 6676 C CG  . GLU A 1 954  ? 100.635 94.380  69.331  1.00 156.14 ? 954  GLU A CG  1 
ATOM 6677 C CD  . GLU A 1 954  ? 99.753  94.956  68.235  1.00 177.47 ? 954  GLU A CD  1 
ATOM 6678 O OE1 . GLU A 1 954  ? 100.195 94.962  67.067  1.00 187.51 ? 954  GLU A OE1 1 
ATOM 6679 O OE2 . GLU A 1 954  ? 98.620  95.388  68.547  1.00 184.25 ? 954  GLU A OE2 1 
ATOM 6680 N N   . ILE A 1 955  ? 100.592 95.033  73.909  1.00 88.21  ? 955  ILE A N   1 
ATOM 6681 C CA  . ILE A 1 955  ? 99.955  95.394  75.175  1.00 78.90  ? 955  ILE A CA  1 
ATOM 6682 C C   . ILE A 1 955  ? 99.478  96.843  75.112  1.00 71.09  ? 955  ILE A C   1 
ATOM 6683 O O   . ILE A 1 955  ? 100.274 97.741  74.853  1.00 74.35  ? 955  ILE A O   1 
ATOM 6684 C CB  . ILE A 1 955  ? 100.908 95.195  76.374  1.00 89.78  ? 955  ILE A CB  1 
ATOM 6685 C CG1 . ILE A 1 955  ? 100.235 95.513  77.712  1.00 102.51 ? 955  ILE A CG1 1 
ATOM 6686 C CG2 . ILE A 1 955  ? 102.177 96.013  76.209  1.00 93.84  ? 955  ILE A CG2 1 
ATOM 6687 C CD1 . ILE A 1 955  ? 101.110 95.303  78.926  1.00 116.45 ? 955  ILE A CD1 1 
ATOM 6688 N N   . ARG A 1 956  ? 98.183  97.082  75.367  1.00 68.41  ? 956  ARG A N   1 
ATOM 6689 C CA  . ARG A 1 956  ? 97.646  98.436  75.393  1.00 70.33  ? 956  ARG A CA  1 
ATOM 6690 C C   . ARG A 1 956  ? 97.775  99.015  76.799  1.00 74.17  ? 956  ARG A C   1 
ATOM 6691 O O   . ARG A 1 956  ? 97.764  98.262  77.769  1.00 91.28  ? 956  ARG A O   1 
ATOM 6692 C CB  . ARG A 1 956  ? 96.198  98.410  74.909  1.00 71.84  ? 956  ARG A CB  1 
ATOM 6693 C CG  . ARG A 1 956  ? 96.085  97.937  73.468  1.00 85.45  ? 956  ARG A CG  1 
ATOM 6694 C CD  . ARG A 1 956  ? 94.689  97.988  72.888  1.00 97.90  ? 956  ARG A CD  1 
ATOM 6695 N NE  . ARG A 1 956  ? 94.713  97.507  71.515  1.00 111.35 ? 956  ARG A NE  1 
ATOM 6696 C CZ  . ARG A 1 956  ? 93.640  97.400  70.743  1.00 136.94 ? 956  ARG A CZ  1 
ATOM 6697 N NH1 . ARG A 1 956  ? 93.747  96.935  69.510  1.00 155.68 ? 956  ARG A NH1 1 
ATOM 6698 N NH2 . ARG A 1 956  ? 92.457  97.734  71.228  1.00 133.21 ? 956  ARG A NH2 1 
ATOM 6699 N N   . SER A 1 957  ? 97.912  100.344 76.905  1.00 67.86  ? 957  SER A N   1 
ATOM 6700 C CA  . SER A 1 957  ? 98.158  100.993 78.189  1.00 65.71  ? 957  SER A CA  1 
ATOM 6701 C C   . SER A 1 957  ? 97.107  102.064 78.480  1.00 65.63  ? 957  SER A C   1 
ATOM 6702 O O   . SER A 1 957  ? 97.417  103.253 78.425  1.00 76.49  ? 957  SER A O   1 
ATOM 6703 C CB  . SER A 1 957  ? 99.546  101.596 78.238  1.00 65.51  ? 957  SER A CB  1 
ATOM 6704 O OG  . SER A 1 957  ? 100.543 100.619 77.984  1.00 69.32  ? 957  SER A OG  1 
ATOM 6705 N N   . PHE A 1 958  ? 95.880  101.639 78.819  1.00 57.54  ? 958  PHE A N   1 
ATOM 6706 C CA  . PHE A 1 958  ? 94.785  102.568 79.069  1.00 57.36  ? 958  PHE A CA  1 
ATOM 6707 C C   . PHE A 1 958  ? 94.973  103.291 80.400  1.00 65.34  ? 958  PHE A C   1 
ATOM 6708 O O   . PHE A 1 958  ? 95.178  102.636 81.412  1.00 76.61  ? 958  PHE A O   1 
ATOM 6709 C CB  . PHE A 1 958  ? 93.448  101.835 79.148  1.00 57.35  ? 958  PHE A CB  1 
ATOM 6710 C CG  . PHE A 1 958  ? 93.077  101.036 77.932  1.00 68.03  ? 958  PHE A CG  1 
ATOM 6711 C CD1 . PHE A 1 958  ? 93.852  101.074 76.788  1.00 84.82  ? 958  PHE A CD1 1 
ATOM 6712 C CD2 . PHE A 1 958  ? 91.949  100.232 77.940  1.00 76.61  ? 958  PHE A CD2 1 
ATOM 6713 C CE1 . PHE A 1 958  ? 93.505  100.325 75.677  1.00 109.16 ? 958  PHE A CE1 1 
ATOM 6714 C CE2 . PHE A 1 958  ? 91.602  99.487  76.825  1.00 88.14  ? 958  PHE A CE2 1 
ATOM 6715 C CZ  . PHE A 1 958  ? 92.385  99.532  75.700  1.00 107.32 ? 958  PHE A CZ  1 
ATOM 6716 N N   . VAL A 1 959  ? 94.884  104.631 80.408  1.00 67.71  ? 959  VAL A N   1 
ATOM 6717 C CA  . VAL A 1 959  ? 94.915  105.409 81.643  1.00 66.89  ? 959  VAL A CA  1 
ATOM 6718 C C   . VAL A 1 959  ? 93.557  105.289 82.329  1.00 66.80  ? 959  VAL A C   1 
ATOM 6719 O O   . VAL A 1 959  ? 92.558  105.019 81.676  1.00 70.99  ? 959  VAL A O   1 
ATOM 6720 C CB  . VAL A 1 959  ? 95.278  106.880 81.386  1.00 76.55  ? 959  VAL A CB  1 
ATOM 6721 C CG1 . VAL A 1 959  ? 94.214  107.591 80.556  1.00 91.44  ? 959  VAL A CG1 1 
ATOM 6722 C CG2 . VAL A 1 959  ? 95.546  107.629 82.681  1.00 76.39  ? 959  VAL A CG2 1 
ATOM 6723 N N   . GLU A 1 960  ? 93.529  105.461 83.653  1.00 67.70  ? 960  GLU A N   1 
ATOM 6724 C CA  . GLU A 1 960  ? 92.401  105.023 84.463  1.00 76.95  ? 960  GLU A CA  1 
ATOM 6725 C C   . GLU A 1 960  ? 91.096  105.655 83.986  1.00 84.84  ? 960  GLU A C   1 
ATOM 6726 O O   . GLU A 1 960  ? 90.099  104.954 83.831  1.00 84.08  ? 960  GLU A O   1 
ATOM 6727 C CB  . GLU A 1 960  ? 92.634  105.321 85.946  1.00 81.70  ? 960  GLU A CB  1 
ATOM 6728 C CG  . GLU A 1 960  ? 93.186  106.710 86.219  1.00 89.99  ? 960  GLU A CG  1 
ATOM 6729 C CD  . GLU A 1 960  ? 93.123  107.130 87.674  1.00 95.23  ? 960  GLU A CD  1 
ATOM 6730 O OE1 . GLU A 1 960  ? 91.998  107.299 88.192  1.00 90.70  ? 960  GLU A OE1 1 
ATOM 6731 O OE2 . GLU A 1 960  ? 94.199  107.261 88.290  1.00 92.70  ? 960  GLU A OE2 1 
ATOM 6732 N N   . THR A 1 961  ? 91.102  106.974 83.764  1.00 93.01  ? 961  THR A N   1 
ATOM 6733 C CA  . THR A 1 961  ? 89.878  107.702 83.475  1.00 98.45  ? 961  THR A CA  1 
ATOM 6734 C C   . THR A 1 961  ? 89.196  107.057 82.273  1.00 101.98 ? 961  THR A C   1 
ATOM 6735 O O   . THR A 1 961  ? 88.031  106.670 82.342  1.00 107.43 ? 961  THR A O   1 
ATOM 6736 C CB  . THR A 1 961  ? 90.166  109.193 83.248  1.00 103.42 ? 961  THR A CB  1 
ATOM 6737 O OG1 . THR A 1 961  ? 91.077  109.313 82.156  1.00 105.68 ? 961  THR A OG1 1 
ATOM 6738 C CG2 . THR A 1 961  ? 90.753  109.879 84.463  1.00 105.12 ? 961  THR A CG2 1 
ATOM 6739 N N   . LYS A 1 962  ? 89.957  106.939 81.179  1.00 101.11 ? 962  LYS A N   1 
ATOM 6740 C CA  . LYS A 1 962  ? 89.491  106.320 79.949  1.00 97.37  ? 962  LYS A CA  1 
ATOM 6741 C C   . LYS A 1 962  ? 88.889  104.964 80.292  1.00 85.52  ? 962  LYS A C   1 
ATOM 6742 O O   . LYS A 1 962  ? 87.780  104.642 79.876  1.00 84.36  ? 962  LYS A O   1 
ATOM 6743 C CB  . LYS A 1 962  ? 90.670  106.170 78.982  1.00 99.79  ? 962  LYS A CB  1 
ATOM 6744 C CG  . LYS A 1 962  ? 90.354  106.275 77.496  1.00 109.32 ? 962  LYS A CG  1 
ATOM 6745 C CD  . LYS A 1 962  ? 91.610  106.281 76.639  1.00 123.01 ? 962  LYS A CD  1 
ATOM 6746 C CE  . LYS A 1 962  ? 92.538  107.444 76.942  1.00 129.02 ? 962  LYS A CE  1 
ATOM 6747 N NZ  . LYS A 1 962  ? 93.900  107.231 76.395  1.00 130.30 ? 962  LYS A NZ  1 
ATOM 6748 N N   . ALA A 1 963  ? 89.640  104.203 81.092  1.00 84.03  ? 963  ALA A N   1 
ATOM 6749 C CA  . ALA A 1 963  ? 89.323  102.816 81.367  1.00 93.05  ? 963  ALA A CA  1 
ATOM 6750 C C   . ALA A 1 963  ? 87.910  102.701 81.921  1.00 90.02  ? 963  ALA A C   1 
ATOM 6751 O O   . ALA A 1 963  ? 87.126  101.891 81.443  1.00 88.39  ? 963  ALA A O   1 
ATOM 6752 C CB  . ALA A 1 963  ? 90.345  102.216 82.307  1.00 96.78  ? 963  ALA A CB  1 
ATOM 6753 N N   . ASP A 1 964  ? 87.580  103.475 82.951  1.00 99.56  ? 964  ASP A N   1 
ATOM 6754 C CA  . ASP A 1 964  ? 86.231  103.378 83.469  1.00 124.95 ? 964  ASP A CA  1 
ATOM 6755 C C   . ASP A 1 964  ? 85.286  103.503 82.281  1.00 118.87 ? 964  ASP A C   1 
ATOM 6756 O O   . ASP A 1 964  ? 84.479  102.610 82.036  1.00 121.25 ? 964  ASP A O   1 
ATOM 6757 C CB  . ASP A 1 964  ? 85.965  104.395 84.580  1.00 161.90 ? 964  ASP A CB  1 
ATOM 6758 C CG  . ASP A 1 964  ? 86.672  104.050 85.881  1.00 195.43 ? 964  ASP A CG  1 
ATOM 6759 O OD1 . ASP A 1 964  ? 87.920  103.984 85.863  1.00 215.05 ? 964  ASP A OD1 1 
ATOM 6760 O OD2 . ASP A 1 964  ? 85.974  103.837 86.898  1.00 205.77 ? 964  ASP A OD2 1 
ATOM 6761 N N   . SER A 1 965  ? 85.456  104.581 81.506  1.00 115.25 ? 965  SER A N   1 
ATOM 6762 C CA  . SER A 1 965  ? 84.555  104.879 80.406  1.00 116.55 ? 965  SER A CA  1 
ATOM 6763 C C   . SER A 1 965  ? 84.394  103.649 79.515  1.00 107.04 ? 965  SER A C   1 
ATOM 6764 O O   . SER A 1 965  ? 83.276  103.218 79.243  1.00 102.40 ? 965  SER A O   1 
ATOM 6765 C CB  . SER A 1 965  ? 85.013  106.085 79.624  1.00 123.09 ? 965  SER A CB  1 
ATOM 6766 O OG  . SER A 1 965  ? 85.116  107.222 80.469  1.00 126.98 ? 965  SER A OG  1 
ATOM 6767 N N   . ILE A 1 966  ? 85.520  103.062 79.099  1.00 97.21  ? 966  ILE A N   1 
ATOM 6768 C CA  . ILE A 1 966  ? 85.467  101.869 78.273  1.00 89.03  ? 966  ILE A CA  1 
ATOM 6769 C C   . ILE A 1 966  ? 84.569  100.867 78.989  1.00 85.36  ? 966  ILE A C   1 
ATOM 6770 O O   . ILE A 1 966  ? 83.671  100.303 78.381  1.00 82.15  ? 966  ILE A O   1 
ATOM 6771 C CB  . ILE A 1 966  ? 86.872  101.292 77.988  1.00 95.66  ? 966  ILE A CB  1 
ATOM 6772 C CG1 . ILE A 1 966  ? 87.878  102.389 77.621  1.00 101.79 ? 966  ILE A CG1 1 
ATOM 6773 C CG2 . ILE A 1 966  ? 86.809  100.198 76.927  1.00 101.94 ? 966  ILE A CG2 1 
ATOM 6774 C CD1 . ILE A 1 966  ? 89.158  101.884 77.006  1.00 101.30 ? 966  ILE A CD1 1 
ATOM 6775 N N   . ILE A 1 967  ? 84.792  100.710 80.300  1.00 91.15  ? 967  ILE A N   1 
ATOM 6776 C CA  . ILE A 1 967  ? 84.134  99.688  81.098  1.00 95.13  ? 967  ILE A CA  1 
ATOM 6777 C C   . ILE A 1 967  ? 82.634  99.959  81.197  1.00 108.47 ? 967  ILE A C   1 
ATOM 6778 O O   . ILE A 1 967  ? 81.864  99.025  81.405  1.00 114.81 ? 967  ILE A O   1 
ATOM 6779 C CB  . ILE A 1 967  ? 84.782  99.578  82.493  1.00 93.84  ? 967  ILE A CB  1 
ATOM 6780 C CG1 . ILE A 1 967  ? 86.242  99.127  82.390  1.00 95.92  ? 967  ILE A CG1 1 
ATOM 6781 C CG2 . ILE A 1 967  ? 83.962  98.655  83.389  1.00 98.65  ? 967  ILE A CG2 1 
ATOM 6782 C CD1 . ILE A 1 967  ? 86.987  99.065  83.710  1.00 97.52  ? 967  ILE A CD1 1 
ATOM 6783 N N   . ARG A 1 968  ? 82.215  101.225 81.070  1.00 122.94 ? 968  ARG A N   1 
ATOM 6784 C CA  . ARG A 1 968  ? 80.801  101.556 81.179  1.00 138.35 ? 968  ARG A CA  1 
ATOM 6785 C C   . ARG A 1 968  ? 80.147  101.598 79.797  1.00 143.53 ? 968  ARG A C   1 
ATOM 6786 O O   . ARG A 1 968  ? 79.009  101.154 79.660  1.00 143.19 ? 968  ARG A O   1 
ATOM 6787 C CB  . ARG A 1 968  ? 80.576  102.848 81.980  1.00 150.90 ? 968  ARG A CB  1 
ATOM 6788 C CG  . ARG A 1 968  ? 81.373  104.058 81.513  1.00 159.91 ? 968  ARG A CG  1 
ATOM 6789 C CD  . ARG A 1 968  ? 81.061  105.342 82.267  1.00 162.77 ? 968  ARG A CD  1 
ATOM 6790 N NE  . ARG A 1 968  ? 81.788  105.470 83.526  1.00 167.66 ? 968  ARG A NE  1 
ATOM 6791 C CZ  . ARG A 1 968  ? 81.449  104.888 84.675  1.00 176.75 ? 968  ARG A CZ  1 
ATOM 6792 N NH1 . ARG A 1 968  ? 80.314  104.220 84.782  1.00 180.53 ? 968  ARG A NH1 1 
ATOM 6793 N NH2 . ARG A 1 968  ? 82.238  105.005 85.731  1.00 177.43 ? 968  ARG A NH2 1 
ATOM 6794 N N   . GLN A 1 969  ? 80.851  102.108 78.775  1.00 146.98 ? 969  GLN A N   1 
ATOM 6795 C CA  . GLN A 1 969  ? 80.250  102.267 77.457  1.00 156.47 ? 969  GLN A CA  1 
ATOM 6796 C C   . GLN A 1 969  ? 79.850  100.898 76.906  1.00 162.38 ? 969  GLN A C   1 
ATOM 6797 O O   . GLN A 1 969  ? 78.692  100.688 76.549  1.00 161.45 ? 969  GLN A O   1 
ATOM 6798 C CB  . GLN A 1 969  ? 81.190  103.015 76.509  1.00 164.79 ? 969  GLN A CB  1 
ATOM 6799 C CG  . GLN A 1 969  ? 81.317  104.497 76.836  1.00 179.08 ? 969  GLN A CG  1 
ATOM 6800 C CD  . GLN A 1 969  ? 82.234  105.241 75.894  1.00 196.49 ? 969  GLN A CD  1 
ATOM 6801 O OE1 . GLN A 1 969  ? 82.842  104.661 74.996  1.00 210.88 ? 969  GLN A OE1 1 
ATOM 6802 N NE2 . GLN A 1 969  ? 82.347  106.543 76.099  1.00 197.68 ? 969  GLN A NE2 1 
ATOM 6803 N N   . LYS A 1 970  ? 80.822  99.978  76.840  1.00 169.08 ? 970  LYS A N   1 
ATOM 6804 C CA  . LYS A 1 970  ? 80.562  98.586  76.499  1.00 165.31 ? 970  LYS A CA  1 
ATOM 6805 C C   . LYS A 1 970  ? 81.435  97.687  77.379  1.00 157.49 ? 970  LYS A C   1 
ATOM 6806 O O   . LYS A 1 970  ? 82.662  97.764  77.337  1.00 147.78 ? 970  LYS A O   1 
ATOM 6807 C CB  . LYS A 1 970  ? 80.751  98.328  74.996  1.00 166.31 ? 970  LYS A CB  1 
ATOM 6808 C CG  . LYS A 1 970  ? 81.528  99.377  74.204  1.00 163.27 ? 970  LYS A CG  1 
ATOM 6809 C CD  . LYS A 1 970  ? 83.033  99.333  74.375  1.00 147.93 ? 970  LYS A CD  1 
ATOM 6810 C CE  . LYS A 1 970  ? 83.737  100.314 73.463  1.00 138.58 ? 970  LYS A CE  1 
ATOM 6811 N NZ  . LYS A 1 970  ? 85.209  100.203 73.568  1.00 138.49 ? 970  LYS A NZ  1 
ATOM 6812 N N   . PRO A 1 971  ? 80.833  96.826  78.231  1.00 148.73 ? 971  PRO A N   1 
ATOM 6813 C CA  . PRO A 1 971  ? 81.609  95.996  79.154  1.00 129.40 ? 971  PRO A CA  1 
ATOM 6814 C C   . PRO A 1 971  ? 82.460  94.958  78.434  1.00 109.54 ? 971  PRO A C   1 
ATOM 6815 O O   . PRO A 1 971  ? 83.646  94.831  78.711  1.00 100.67 ? 971  PRO A O   1 
ATOM 6816 C CB  . PRO A 1 971  ? 80.538  95.301  80.011  1.00 145.60 ? 971  PRO A CB  1 
ATOM 6817 C CG  . PRO A 1 971  ? 79.283  95.334  79.164  1.00 157.54 ? 971  PRO A CG  1 
ATOM 6818 C CD  . PRO A 1 971  ? 79.381  96.606  78.350  1.00 159.95 ? 971  PRO A CD  1 
ATOM 6819 N N   . VAL A 1 972  ? 81.828  94.263  77.483  1.00 103.66 ? 972  VAL A N   1 
ATOM 6820 C CA  . VAL A 1 972  ? 82.292  92.979  76.989  1.00 104.63 ? 972  VAL A CA  1 
ATOM 6821 C C   . VAL A 1 972  ? 83.606  93.134  76.231  1.00 101.28 ? 972  VAL A C   1 
ATOM 6822 O O   . VAL A 1 972  ? 84.479  92.280  76.328  1.00 106.46 ? 972  VAL A O   1 
ATOM 6823 C CB  . VAL A 1 972  ? 81.218  92.321  76.105  1.00 115.05 ? 972  VAL A CB  1 
ATOM 6824 C CG1 . VAL A 1 972  ? 81.750  91.091  75.381  1.00 123.48 ? 972  VAL A CG1 1 
ATOM 6825 C CG2 . VAL A 1 972  ? 79.971  91.981  76.910  1.00 118.73 ? 972  VAL A CG2 1 
ATOM 6826 N N   . ASP A 1 973  ? 83.747  94.225  75.482  1.00 100.91 ? 973  ASP A N   1 
ATOM 6827 C CA  . ASP A 1 973  ? 84.828  94.332  74.520  1.00 107.19 ? 973  ASP A CA  1 
ATOM 6828 C C   . ASP A 1 973  ? 86.177  94.317  75.238  1.00 91.41  ? 973  ASP A C   1 
ATOM 6829 O O   . ASP A 1 973  ? 87.085  93.611  74.810  1.00 94.34  ? 973  ASP A O   1 
ATOM 6830 C CB  . ASP A 1 973  ? 84.609  95.539  73.605  1.00 132.74 ? 973  ASP A CB  1 
ATOM 6831 C CG  . ASP A 1 973  ? 83.299  95.453  72.834  1.00 155.21 ? 973  ASP A CG  1 
ATOM 6832 O OD1 . ASP A 1 973  ? 82.522  94.502  73.098  1.00 152.97 ? 973  ASP A OD1 1 
ATOM 6833 O OD2 . ASP A 1 973  ? 83.065  96.327  71.974  1.00 170.54 ? 973  ASP A OD2 1 
ATOM 6834 N N   . LEU A 1 974  ? 86.325  95.063  76.338  1.00 76.48  ? 974  LEU A N   1 
ATOM 6835 C CA  . LEU A 1 974  ? 87.601  95.037  77.033  1.00 66.98  ? 974  LEU A CA  1 
ATOM 6836 C C   . LEU A 1 974  ? 87.929  93.590  77.373  1.00 63.38  ? 974  LEU A C   1 
ATOM 6837 O O   . LEU A 1 974  ? 89.041  93.135  77.131  1.00 67.68  ? 974  LEU A O   1 
ATOM 6838 C CB  . LEU A 1 974  ? 87.574  95.918  78.283  1.00 69.32  ? 974  LEU A CB  1 
ATOM 6839 C CG  . LEU A 1 974  ? 88.917  96.054  79.004  1.00 78.84  ? 974  LEU A CG  1 
ATOM 6840 C CD1 . LEU A 1 974  ? 89.986  96.642  78.091  1.00 78.01  ? 974  LEU A CD1 1 
ATOM 6841 C CD2 . LEU A 1 974  ? 88.782  96.893  80.272  1.00 89.11  ? 974  LEU A CD2 1 
ATOM 6842 N N   . LEU A 1 975  ? 86.934  92.851  77.867  1.00 68.28  ? 975  LEU A N   1 
ATOM 6843 C CA  . LEU A 1 975  ? 87.153  91.468  78.258  1.00 72.51  ? 975  LEU A CA  1 
ATOM 6844 C C   . LEU A 1 975  ? 87.686  90.669  77.072  1.00 76.66  ? 975  LEU A C   1 
ATOM 6845 O O   . LEU A 1 975  ? 88.708  89.999  77.203  1.00 79.31  ? 975  LEU A O   1 
ATOM 6846 C CB  . LEU A 1 975  ? 85.854  90.855  78.787  1.00 72.17  ? 975  LEU A CB  1 
ATOM 6847 C CG  . LEU A 1 975  ? 85.932  89.371  79.121  1.00 75.14  ? 975  LEU A CG  1 
ATOM 6848 C CD1 . LEU A 1 975  ? 86.703  89.174  80.419  1.00 78.51  ? 975  LEU A CD1 1 
ATOM 6849 C CD2 . LEU A 1 975  ? 84.539  88.762  79.177  1.00 79.85  ? 975  LEU A CD2 1 
ATOM 6850 N N   . LYS A 1 976  ? 87.008  90.752  75.920  1.00 77.37  ? 976  LYS A N   1 
ATOM 6851 C CA  . LYS A 1 976  ? 87.391  89.931  74.785  1.00 77.00  ? 976  LYS A CA  1 
ATOM 6852 C C   . LYS A 1 976  ? 88.830  90.265  74.398  1.00 63.69  ? 976  LYS A C   1 
ATOM 6853 O O   . LYS A 1 976  ? 89.617  89.354  74.169  1.00 63.01  ? 976  LYS A O   1 
ATOM 6854 C CB  . LYS A 1 976  ? 86.416  90.092  73.614  1.00 89.70  ? 976  LYS A CB  1 
ATOM 6855 C CG  . LYS A 1 976  ? 86.298  88.875  72.706  1.00 105.27 ? 976  LYS A CG  1 
ATOM 6856 C CD  . LYS A 1 976  ? 85.843  87.615  73.420  1.00 117.08 ? 976  LYS A CD  1 
ATOM 6857 C CE  . LYS A 1 976  ? 84.571  87.800  74.223  1.00 127.39 ? 976  LYS A CE  1 
ATOM 6858 N NZ  . LYS A 1 976  ? 83.457  88.307  73.384  1.00 130.51 ? 976  LYS A NZ  1 
ATOM 6859 N N   . TYR A 1 977  ? 89.184  91.556  74.355  1.00 59.02  ? 977  TYR A N   1 
ATOM 6860 C CA  . TYR A 1 977  ? 90.553  91.935  74.042  1.00 61.86  ? 977  TYR A CA  1 
ATOM 6861 C C   . TYR A 1 977  ? 91.506  91.327  75.060  1.00 62.85  ? 977  TYR A C   1 
ATOM 6862 O O   . TYR A 1 977  ? 92.640  91.004  74.718  1.00 67.55  ? 977  TYR A O   1 
ATOM 6863 C CB  . TYR A 1 977  ? 90.797  93.449  74.058  1.00 65.57  ? 977  TYR A CB  1 
ATOM 6864 C CG  . TYR A 1 977  ? 92.232  93.830  73.784  1.00 66.82  ? 977  TYR A CG  1 
ATOM 6865 C CD1 . TYR A 1 977  ? 92.813  93.524  72.569  1.00 74.79  ? 977  TYR A CD1 1 
ATOM 6866 C CD2 . TYR A 1 977  ? 93.022  94.453  74.736  1.00 69.38  ? 977  TYR A CD2 1 
ATOM 6867 C CE1 . TYR A 1 977  ? 94.131  93.846  72.294  1.00 86.65  ? 977  TYR A CE1 1 
ATOM 6868 C CE2 . TYR A 1 977  ? 94.342  94.780  74.479  1.00 76.15  ? 977  TYR A CE2 1 
ATOM 6869 C CZ  . TYR A 1 977  ? 94.903  94.470  73.255  1.00 87.28  ? 977  TYR A CZ  1 
ATOM 6870 O OH  . TYR A 1 977  ? 96.216  94.767  72.958  1.00 100.41 ? 977  TYR A OH  1 
ATOM 6871 N N   . ASN A 1 978  ? 91.060  91.221  76.315  1.00 62.79  ? 978  ASN A N   1 
ATOM 6872 C CA  . ASN A 1 978  ? 91.956  90.782  77.366  1.00 67.33  ? 978  ASN A CA  1 
ATOM 6873 C C   . ASN A 1 978  ? 92.245  89.297  77.203  1.00 72.03  ? 978  ASN A C   1 
ATOM 6874 O O   . ASN A 1 978  ? 93.404  88.903  77.260  1.00 79.85  ? 978  ASN A O   1 
ATOM 6875 C CB  . ASN A 1 978  ? 91.464  91.184  78.751  1.00 76.01  ? 978  ASN A CB  1 
ATOM 6876 C CG  . ASN A 1 978  ? 91.770  92.640  79.028  1.00 87.97  ? 978  ASN A CG  1 
ATOM 6877 O OD1 . ASN A 1 978  ? 92.894  93.090  78.814  1.00 70.24  ? 978  ASN A OD1 1 
ATOM 6878 N ND2 . ASN A 1 978  ? 90.779  93.389  79.484  1.00 97.55  ? 978  ASN A ND2 1 
ATOM 6879 N N   . GLN A 1 979  ? 91.234  88.468  76.949  1.00 68.18  ? 979  GLN A N   1 
ATOM 6880 C CA  . GLN A 1 979  ? 91.565  87.133  76.487  1.00 62.65  ? 979  GLN A CA  1 
ATOM 6881 C C   . GLN A 1 979  ? 92.463  87.331  75.265  1.00 62.72  ? 979  GLN A C   1 
ATOM 6882 O O   . GLN A 1 979  ? 92.076  88.040  74.342  1.00 72.99  ? 979  GLN A O   1 
ATOM 6883 C CB  . GLN A 1 979  ? 90.290  86.345  76.208  1.00 64.52  ? 979  GLN A CB  1 
ATOM 6884 C CG  . GLN A 1 979  ? 90.550  84.912  75.775  1.00 79.33  ? 979  GLN A CG  1 
ATOM 6885 C CD  . GLN A 1 979  ? 89.283  84.191  75.375  1.00 102.33 ? 979  GLN A CD  1 
ATOM 6886 O OE1 . GLN A 1 979  ? 89.313  83.044  74.930  1.00 111.46 ? 979  GLN A OE1 1 
ATOM 6887 N NE2 . GLN A 1 979  ? 88.152  84.866  75.523  1.00 107.18 ? 979  GLN A NE2 1 
ATOM 6888 N N   . LYS A 1 980  ? 93.700  86.830  75.322  1.00 60.27  ? 980  LYS A N   1 
ATOM 6889 C CA  . LYS A 1 980  ? 94.618  86.854  74.192  1.00 66.93  ? 980  LYS A CA  1 
ATOM 6890 C C   . LYS A 1 980  ? 95.331  88.195  74.027  1.00 63.09  ? 980  LYS A C   1 
ATOM 6891 O O   . LYS A 1 980  ? 95.952  88.406  72.988  1.00 71.79  ? 980  LYS A O   1 
ATOM 6892 C CB  . LYS A 1 980  ? 93.903  86.536  72.872  1.00 81.79  ? 980  LYS A CB  1 
ATOM 6893 C CG  . LYS A 1 980  ? 93.114  85.230  72.845  1.00 102.05 ? 980  LYS A CG  1 
ATOM 6894 C CD  . LYS A 1 980  ? 92.370  84.975  71.543  1.00 116.88 ? 980  LYS A CD  1 
ATOM 6895 C CE  . LYS A 1 980  ? 93.197  84.272  70.483  1.00 129.55 ? 980  LYS A CE  1 
ATOM 6896 N NZ  . LYS A 1 980  ? 94.287  85.124  69.948  1.00 133.64 ? 980  LYS A NZ  1 
ATOM 6897 N N   . GLY A 1 981  ? 95.268  89.091  75.020  1.00 63.83  ? 981  GLY A N   1 
ATOM 6898 C CA  . GLY A 1 981  ? 95.971  90.370  74.940  1.00 69.02  ? 981  GLY A CA  1 
ATOM 6899 C C   . GLY A 1 981  ? 96.192  90.991  76.320  1.00 70.26  ? 981  GLY A C   1 
ATOM 6900 O O   . GLY A 1 981  ? 95.465  90.677  77.252  1.00 79.18  ? 981  GLY A O   1 
ATOM 6901 N N   . LEU A 1 982  ? 97.200  91.857  76.460  1.00 63.49  ? 982  LEU A N   1 
ATOM 6902 C CA  . LEU A 1 982  ? 97.538  92.406  77.765  1.00 62.88  ? 982  LEU A CA  1 
ATOM 6903 C C   . LEU A 1 982  ? 97.127  93.876  77.836  1.00 67.77  ? 982  LEU A C   1 
ATOM 6904 O O   . LEU A 1 982  ? 97.453  94.636  76.927  1.00 75.23  ? 982  LEU A O   1 
ATOM 6905 C CB  . LEU A 1 982  ? 99.044  92.257  77.987  1.00 61.46  ? 982  LEU A CB  1 
ATOM 6906 C CG  . LEU A 1 982  ? 99.586  90.832  77.958  1.00 69.67  ? 982  LEU A CG  1 
ATOM 6907 C CD1 . LEU A 1 982  ? 100.999 90.786  78.528  1.00 74.11  ? 982  LEU A CD1 1 
ATOM 6908 C CD2 . LEU A 1 982  ? 98.680  89.876  78.723  1.00 68.80  ? 982  LEU A CD2 1 
ATOM 6909 N N   . THR A 1 983  ? 96.428  94.273  78.919  1.00 58.17  ? 983  THR A N   1 
ATOM 6910 C CA  . THR A 1 983  ? 96.096  95.672  79.174  1.00 48.28  ? 983  THR A CA  1 
ATOM 6911 C C   . THR A 1 983  ? 96.667  96.119  80.512  1.00 41.93  ? 983  THR A C   1 
ATOM 6912 O O   . THR A 1 983  ? 96.431  95.446  81.508  1.00 53.66  ? 983  THR A O   1 
ATOM 6913 C CB  . THR A 1 983  ? 94.583  95.908  79.197  1.00 49.42  ? 983  THR A CB  1 
ATOM 6914 O OG1 . THR A 1 983  ? 93.999  95.069  80.184  1.00 44.39  ? 983  THR A OG1 1 
ATOM 6915 C CG2 . THR A 1 983  ? 93.923  95.630  77.867  1.00 58.90  ? 983  THR A CG2 1 
ATOM 6916 N N   . ARG A 1 984  ? 97.368  97.258  80.537  1.00 35.38  ? 984  ARG A N   1 
ATOM 6917 C CA  . ARG A 1 984  ? 97.957  97.784  81.761  1.00 34.11  ? 984  ARG A CA  1 
ATOM 6918 C C   . ARG A 1 984  ? 97.323  99.125  82.131  1.00 34.99  ? 984  ARG A C   1 
ATOM 6919 O O   . ARG A 1 984  ? 97.790  100.174 81.692  1.00 41.06  ? 984  ARG A O   1 
ATOM 6920 C CB  . ARG A 1 984  ? 99.469  97.961  81.594  1.00 33.28  ? 984  ARG A CB  1 
ATOM 6921 C CG  . ARG A 1 984  ? 100.172 98.534  82.817  1.00 33.86  ? 984  ARG A CG  1 
ATOM 6922 C CD  . ARG A 1 984  ? 101.635 98.786  82.538  1.00 38.60  ? 984  ARG A CD  1 
ATOM 6923 N NE  . ARG A 1 984  ? 102.323 99.110  83.779  1.00 50.39  ? 984  ARG A NE  1 
ATOM 6924 C CZ  . ARG A 1 984  ? 102.903 100.279 84.025  1.00 65.46  ? 984  ARG A CZ  1 
ATOM 6925 N NH1 . ARG A 1 984  ? 103.019 101.161 83.048  1.00 68.90  ? 984  ARG A NH1 1 
ATOM 6926 N NH2 . ARG A 1 984  ? 103.379 100.555 85.233  1.00 71.98  ? 984  ARG A NH2 1 
ATOM 6927 N N   . VAL A 1 985  ? 96.285  99.101  82.974  1.00 29.72  ? 985  VAL A N   1 
ATOM 6928 C CA  . VAL A 1 985  ? 95.669  100.322 83.479  1.00 28.18  ? 985  VAL A CA  1 
ATOM 6929 C C   . VAL A 1 985  ? 96.686  101.043 84.352  1.00 29.36  ? 985  VAL A C   1 
ATOM 6930 O O   . VAL A 1 985  ? 97.521  100.370 84.936  1.00 37.37  ? 985  VAL A O   1 
ATOM 6931 C CB  . VAL A 1 985  ? 94.401  99.985  84.268  1.00 28.29  ? 985  VAL A CB  1 
ATOM 6932 C CG1 . VAL A 1 985  ? 93.632  101.239 84.640  1.00 30.60  ? 985  VAL A CG1 1 
ATOM 6933 C CG2 . VAL A 1 985  ? 93.516  99.021  83.497  1.00 29.72  ? 985  VAL A CG2 1 
ATOM 6934 N N   . TYR A 1 986  ? 96.701  102.381 84.378  1.00 32.64  ? 986  TYR A N   1 
ATOM 6935 C CA  . TYR A 1 986  ? 97.715  103.080 85.161  1.00 44.67  ? 986  TYR A CA  1 
ATOM 6936 C C   . TYR A 1 986  ? 97.141  104.306 85.875  1.00 48.19  ? 986  TYR A C   1 
ATOM 6937 O O   . TYR A 1 986  ? 96.171  104.886 85.425  1.00 54.13  ? 986  TYR A O   1 
ATOM 6938 C CB  . TYR A 1 986  ? 98.977  103.402 84.340  1.00 56.73  ? 986  TYR A CB  1 
ATOM 6939 C CG  . TYR A 1 986  ? 98.881  104.384 83.193  1.00 67.52  ? 986  TYR A CG  1 
ATOM 6940 C CD1 . TYR A 1 986  ? 98.127  104.108 82.064  1.00 71.02  ? 986  TYR A CD1 1 
ATOM 6941 C CD2 . TYR A 1 986  ? 99.640  105.544 83.186  1.00 73.26  ? 986  TYR A CD2 1 
ATOM 6942 C CE1 . TYR A 1 986  ? 98.068  104.983 80.995  1.00 75.93  ? 986  TYR A CE1 1 
ATOM 6943 C CE2 . TYR A 1 986  ? 99.594  106.431 82.126  1.00 82.31  ? 986  TYR A CE2 1 
ATOM 6944 C CZ  . TYR A 1 986  ? 98.800  106.152 81.028  1.00 85.49  ? 986  TYR A CZ  1 
ATOM 6945 O OH  . TYR A 1 986  ? 98.740  107.021 79.963  1.00 98.67  ? 986  TYR A OH  1 
ATOM 6946 N N   . PRO A 1 987  ? 97.724  104.730 87.021  1.00 51.11  ? 987  PRO A N   1 
ATOM 6947 C CA  . PRO A 1 987  ? 97.230  105.872 87.788  1.00 54.31  ? 987  PRO A CA  1 
ATOM 6948 C C   . PRO A 1 987  ? 97.327  107.206 87.057  1.00 68.80  ? 987  PRO A C   1 
ATOM 6949 O O   . PRO A 1 987  ? 98.337  107.478 86.404  1.00 78.62  ? 987  PRO A O   1 
ATOM 6950 C CB  . PRO A 1 987  ? 98.181  105.927 88.996  1.00 56.87  ? 987  PRO A CB  1 
ATOM 6951 C CG  . PRO A 1 987  ? 98.703  104.526 89.109  1.00 56.74  ? 987  PRO A CG  1 
ATOM 6952 C CD  . PRO A 1 987  ? 98.888  104.112 87.668  1.00 54.53  ? 987  PRO A CD  1 
ATOM 6953 N N   . LYS A 1 988  ? 96.289  108.044 87.217  1.00 67.88  ? 988  LYS A N   1 
ATOM 6954 C CA  . LYS A 1 988  ? 96.204  109.333 86.543  1.00 62.13  ? 988  LYS A CA  1 
ATOM 6955 C C   . LYS A 1 988  ? 97.249  110.279 87.122  1.00 60.94  ? 988  LYS A C   1 
ATOM 6956 O O   . LYS A 1 988  ? 97.743  110.074 88.229  1.00 62.93  ? 988  LYS A O   1 
ATOM 6957 C CB  . LYS A 1 988  ? 94.815  109.961 86.681  1.00 62.78  ? 988  LYS A CB  1 
ATOM 6958 C CG  . LYS A 1 988  ? 94.518  110.597 88.034  1.00 73.65  ? 988  LYS A CG  1 
ATOM 6959 C CD  . LYS A 1 988  ? 93.160  111.283 88.118  1.00 85.70  ? 988  LYS A CD  1 
ATOM 6960 C CE  . LYS A 1 988  ? 91.987  110.323 88.129  1.00 89.12  ? 988  LYS A CE  1 
ATOM 6961 N NZ  . LYS A 1 988  ? 90.692  111.029 88.273  1.00 91.30  ? 988  LYS A NZ  1 
ATOM 6962 N N   . GLY A 1 989  ? 97.570  111.321 86.354  1.00 70.12  ? 989  GLY A N   1 
ATOM 6963 C CA  . GLY A 1 989  ? 98.580  112.290 86.745  1.00 81.67  ? 989  GLY A CA  1 
ATOM 6964 C C   . GLY A 1 989  ? 98.147  113.133 87.941  1.00 83.05  ? 989  GLY A C   1 
ATOM 6965 O O   . GLY A 1 989  ? 98.989  113.567 88.725  1.00 74.19  ? 989  GLY A O   1 
ATOM 6966 N N   . GLN A 1 990  ? 96.829  113.341 88.063  1.00 90.44  ? 990  GLN A N   1 
ATOM 6967 C CA  . GLN A 1 990  ? 96.257  114.146 89.130  1.00 99.41  ? 990  GLN A CA  1 
ATOM 6968 C C   . GLN A 1 990  ? 96.742  113.634 90.484  1.00 95.38  ? 990  GLN A C   1 
ATOM 6969 O O   . GLN A 1 990  ? 97.011  114.421 91.383  1.00 108.22 ? 990  GLN A O   1 
ATOM 6970 C CB  . GLN A 1 990  ? 94.726  114.124 89.088  1.00 112.09 ? 990  GLN A CB  1 
ATOM 6971 C CG  . GLN A 1 990  ? 94.113  114.909 87.933  1.00 139.67 ? 990  GLN A CG  1 
ATOM 6972 C CD  . GLN A 1 990  ? 94.297  114.290 86.566  1.00 164.03 ? 990  GLN A CD  1 
ATOM 6973 O OE1 . GLN A 1 990  ? 94.956  113.269 86.406  1.00 168.74 ? 990  GLN A OE1 1 
ATOM 6974 N NE2 . GLN A 1 990  ? 93.712  114.912 85.554  1.00 176.29 ? 990  GLN A NE2 1 
ATOM 6975 N N   . ARG A 1 991  ? 96.847  112.309 90.629  1.00 76.90  ? 991  ARG A N   1 
ATOM 6976 C CA  . ARG A 1 991  ? 97.148  111.699 91.914  1.00 59.13  ? 991  ARG A CA  1 
ATOM 6977 C C   . ARG A 1 991  ? 98.624  111.875 92.259  1.00 51.60  ? 991  ARG A C   1 
ATOM 6978 O O   . ARG A 1 991  ? 99.398  110.927 92.217  1.00 54.21  ? 991  ARG A O   1 
ATOM 6979 C CB  . ARG A 1 991  ? 96.765  110.216 91.880  1.00 53.69  ? 991  ARG A CB  1 
ATOM 6980 C CG  . ARG A 1 991  ? 95.283  109.950 91.659  1.00 48.10  ? 991  ARG A CG  1 
ATOM 6981 C CD  . ARG A 1 991  ? 95.051  108.456 91.541  1.00 48.40  ? 991  ARG A CD  1 
ATOM 6982 N NE  . ARG A 1 991  ? 93.674  108.089 91.272  1.00 50.91  ? 991  ARG A NE  1 
ATOM 6983 C CZ  . ARG A 1 991  ? 92.666  108.372 92.076  1.00 60.91  ? 991  ARG A CZ  1 
ATOM 6984 N NH1 . ARG A 1 991  ? 92.900  108.946 93.240  1.00 60.69  ? 991  ARG A NH1 1 
ATOM 6985 N NH2 . ARG A 1 991  ? 91.428  108.077 91.719  1.00 71.63  ? 991  ARG A NH2 1 
ATOM 6986 N N   . VAL A 1 992  ? 99.001  113.089 92.650  1.00 54.46  ? 992  VAL A N   1 
ATOM 6987 C CA  . VAL A 1 992  ? 100.315 113.331 93.209  1.00 69.84  ? 992  VAL A CA  1 
ATOM 6988 C C   . VAL A 1 992  ? 100.430 112.551 94.519  1.00 79.94  ? 992  VAL A C   1 
ATOM 6989 O O   . VAL A 1 992  ? 101.499 112.063 94.870  1.00 89.54  ? 992  VAL A O   1 
ATOM 6990 C CB  . VAL A 1 992  ? 100.547 114.830 93.467  1.00 88.86  ? 992  VAL A CB  1 
ATOM 6991 C CG1 . VAL A 1 992  ? 100.361 115.684 92.219  1.00 97.43  ? 992  VAL A CG1 1 
ATOM 6992 C CG2 . VAL A 1 992  ? 99.661  115.341 94.592  1.00 101.16 ? 992  VAL A CG2 1 
ATOM 6993 N N   . ASP A 1 993  ? 99.313  112.466 95.249  1.00 84.82  ? 993  ASP A N   1 
ATOM 6994 C CA  . ASP A 1 993  ? 99.259  111.847 96.562  1.00 91.27  ? 993  ASP A CA  1 
ATOM 6995 C C   . ASP A 1 993  ? 99.598  110.359 96.484  1.00 82.32  ? 993  ASP A C   1 
ATOM 6996 O O   . ASP A 1 993  ? 100.203 109.830 97.410  1.00 91.59  ? 993  ASP A O   1 
ATOM 6997 C CB  . ASP A 1 993  ? 97.882  112.065 97.199  1.00 115.48 ? 993  ASP A CB  1 
ATOM 6998 C CG  . ASP A 1 993  ? 96.718  111.610 96.329  1.00 134.74 ? 993  ASP A CG  1 
ATOM 6999 O OD1 . ASP A 1 993  ? 96.661  110.402 96.021  1.00 132.65 ? 993  ASP A OD1 1 
ATOM 7000 O OD2 . ASP A 1 993  ? 95.881  112.468 95.957  1.00 148.40 ? 993  ASP A OD2 1 
ATOM 7001 N N   . SER A 1 994  ? 99.191  109.694 95.392  1.00 71.36  ? 994  SER A N   1 
ATOM 7002 C CA  . SER A 1 994  ? 99.426  108.272 95.181  1.00 65.72  ? 994  SER A CA  1 
ATOM 7003 C C   . SER A 1 994  ? 98.290  107.422 95.741  1.00 57.44  ? 994  SER A C   1 
ATOM 7004 O O   . SER A 1 994  ? 98.368  106.196 95.730  1.00 60.38  ? 994  SER A O   1 
ATOM 7005 C CB  . SER A 1 994  ? 100.759 107.802 95.732  1.00 69.47  ? 994  SER A CB  1 
ATOM 7006 O OG  . SER A 1 994  ? 101.831 108.476 95.093  1.00 69.67  ? 994  SER A OG  1 
ATOM 7007 N N   . SER A 1 995  ? 97.224  108.040 96.229  1.00 61.90  ? 995  SER A N   1 
ATOM 7008 C CA  . SER A 1 995  ? 96.052  107.239 96.534  1.00 82.78  ? 995  SER A CA  1 
ATOM 7009 C C   . SER A 1 995  ? 95.669  106.509 95.253  1.00 66.70  ? 995  SER A C   1 
ATOM 7010 O O   . SER A 1 995  ? 95.736  107.107 94.190  1.00 69.64  ? 995  SER A O   1 
ATOM 7011 C CB  . SER A 1 995  ? 94.917  108.087 97.049  1.00 110.97 ? 995  SER A CB  1 
ATOM 7012 O OG  . SER A 1 995  ? 94.481  108.992 96.047  1.00 120.20 ? 995  SER A OG  1 
ATOM 7013 N N   . ASN A 1 996  ? 95.270  105.240 95.365  1.00 55.70  ? 996  ASN A N   1 
ATOM 7014 C CA  . ASN A 1 996  ? 95.103  104.393 94.199  1.00 54.25  ? 996  ASN A CA  1 
ATOM 7015 C C   . ASN A 1 996  ? 93.634  104.249 93.809  1.00 49.92  ? 996  ASN A C   1 
ATOM 7016 O O   . ASN A 1 996  ? 92.764  104.121 94.663  1.00 57.74  ? 996  ASN A O   1 
ATOM 7017 C CB  . ASN A 1 996  ? 95.720  103.024 94.461  1.00 65.29  ? 996  ASN A CB  1 
ATOM 7018 C CG  . ASN A 1 996  ? 97.180  103.154 94.834  1.00 74.00  ? 996  ASN A CG  1 
ATOM 7019 O OD1 . ASN A 1 996  ? 97.967  103.718 94.077  1.00 73.99  ? 996  ASN A OD1 1 
ATOM 7020 N ND2 . ASN A 1 996  ? 97.544  102.686 96.014  1.00 77.18  ? 996  ASN A ND2 1 
ATOM 7021 N N   . TYR A 1 997  ? 93.390  104.210 92.496  1.00 46.92  ? 997  TYR A N   1 
ATOM 7022 C CA  . TYR A 1 997  ? 92.072  103.997 91.917  1.00 50.22  ? 997  TYR A CA  1 
ATOM 7023 C C   . TYR A 1 997  ? 91.520  102.616 92.217  1.00 50.76  ? 997  TYR A C   1 
ATOM 7024 O O   . TYR A 1 997  ? 92.272  101.656 92.294  1.00 53.42  ? 997  TYR A O   1 
ATOM 7025 C CB  . TYR A 1 997  ? 92.072  104.050 90.388  1.00 56.27  ? 997  TYR A CB  1 
ATOM 7026 C CG  . TYR A 1 997  ? 93.249  103.401 89.703  1.00 62.20  ? 997  TYR A CG  1 
ATOM 7027 C CD1 . TYR A 1 997  ? 94.507  103.974 89.810  1.00 67.01  ? 997  TYR A CD1 1 
ATOM 7028 C CD2 . TYR A 1 997  ? 93.116  102.268 88.910  1.00 61.30  ? 997  TYR A CD2 1 
ATOM 7029 C CE1 . TYR A 1 997  ? 95.608  103.432 89.182  1.00 68.68  ? 997  TYR A CE1 1 
ATOM 7030 C CE2 . TYR A 1 997  ? 94.218  101.711 88.274  1.00 68.81  ? 997  TYR A CE2 1 
ATOM 7031 C CZ  . TYR A 1 997  ? 95.466  102.301 88.405  1.00 74.31  ? 997  TYR A CZ  1 
ATOM 7032 O OH  . TYR A 1 997  ? 96.584  101.795 87.781  1.00 85.37  ? 997  TYR A OH  1 
ATOM 7033 N N   . ASP A 1 998  ? 90.188  102.534 92.231  1.00 55.61  ? 998  ASP A N   1 
ATOM 7034 C CA  . ASP A 1 998  ? 89.491  101.308 92.561  1.00 63.27  ? 998  ASP A CA  1 
ATOM 7035 C C   . ASP A 1 998  ? 89.863  100.198 91.591  1.00 59.45  ? 998  ASP A C   1 
ATOM 7036 O O   . ASP A 1 998  ? 89.329  100.093 90.491  1.00 62.33  ? 998  ASP A O   1 
ATOM 7037 C CB  . ASP A 1 998  ? 87.972  101.452 92.537  1.00 82.38  ? 998  ASP A CB  1 
ATOM 7038 C CG  . ASP A 1 998  ? 87.300  100.203 93.079  1.00 94.05  ? 998  ASP A CG  1 
ATOM 7039 O OD1 . ASP A 1 998  ? 87.610  99.111  92.566  1.00 92.73  ? 998  ASP A OD1 1 
ATOM 7040 O OD2 . ASP A 1 998  ? 86.506  100.328 94.035  1.00 105.34 ? 998  ASP A OD2 1 
ATOM 7041 N N   . PRO A 1 999  ? 90.728  99.270  92.016  1.00 59.52  ? 999  PRO A N   1 
ATOM 7042 C CA  . PRO A 1 999  ? 91.225  98.255  91.109  1.00 51.70  ? 999  PRO A CA  1 
ATOM 7043 C C   . PRO A 1 999  ? 90.070  97.377  90.660  1.00 45.20  ? 999  PRO A C   1 
ATOM 7044 O O   . PRO A 1 999  ? 90.065  96.964  89.523  1.00 46.31  ? 999  PRO A O   1 
ATOM 7045 C CB  . PRO A 1 999  ? 92.271  97.501  91.939  1.00 62.01  ? 999  PRO A CB  1 
ATOM 7046 C CG  . PRO A 1 999  ? 91.812  97.696  93.370  1.00 73.07  ? 999  PRO A CG  1 
ATOM 7047 C CD  . PRO A 1 999  ? 91.179  99.074  93.400  1.00 75.27  ? 999  PRO A CD  1 
ATOM 7048 N N   . PHE A 1 1000 ? 89.060  97.168  91.506  1.00 49.87  ? 1000 PHE A N   1 
ATOM 7049 C CA  . PHE A 1 1000 ? 88.179  96.013  91.380  1.00 66.32  ? 1000 PHE A CA  1 
ATOM 7050 C C   . PHE A 1 1000 ? 87.460  95.936  90.028  1.00 76.24  ? 1000 PHE A C   1 
ATOM 7051 O O   . PHE A 1 1000 ? 87.351  94.845  89.471  1.00 81.84  ? 1000 PHE A O   1 
ATOM 7052 C CB  . PHE A 1 1000 ? 87.148  95.981  92.514  1.00 76.64  ? 1000 PHE A CB  1 
ATOM 7053 C CG  . PHE A 1 1000 ? 86.635  94.602  92.836  1.00 86.29  ? 1000 PHE A CG  1 
ATOM 7054 C CD1 . PHE A 1 1000 ? 85.899  93.873  91.908  1.00 98.86  ? 1000 PHE A CD1 1 
ATOM 7055 C CD2 . PHE A 1 1000 ? 86.914  94.014  94.059  1.00 96.72  ? 1000 PHE A CD2 1 
ATOM 7056 C CE1 . PHE A 1 1000 ? 85.449  92.592  92.199  1.00 115.68 ? 1000 PHE A CE1 1 
ATOM 7057 C CE2 . PHE A 1 1000 ? 86.461  92.734  94.349  1.00 115.86 ? 1000 PHE A CE2 1 
ATOM 7058 C CZ  . PHE A 1 1000 ? 85.733  92.023  93.420  1.00 125.52 ? 1000 PHE A CZ  1 
ATOM 7059 N N   . ARG A 1 1001 ? 86.899  97.044  89.520  1.00 82.35  ? 1001 ARG A N   1 
ATOM 7060 C CA  . ARG A 1 1001 ? 86.129  96.972  88.283  1.00 83.01  ? 1001 ARG A CA  1 
ATOM 7061 C C   . ARG A 1 1001 ? 86.990  96.380  87.172  1.00 67.92  ? 1001 ARG A C   1 
ATOM 7062 O O   . ARG A 1 1001 ? 86.622  95.384  86.550  1.00 67.16  ? 1001 ARG A O   1 
ATOM 7063 C CB  . ARG A 1 1001 ? 85.626  98.349  87.845  1.00 102.49 ? 1001 ARG A CB  1 
ATOM 7064 C CG  . ARG A 1 1001 ? 84.499  98.902  88.703  1.00 122.55 ? 1001 ARG A CG  1 
ATOM 7065 C CD  . ARG A 1 1001 ? 83.828  100.100 88.054  1.00 136.38 ? 1001 ARG A CD  1 
ATOM 7066 N NE  . ARG A 1 1001 ? 82.861  100.735 88.941  1.00 160.00 ? 1001 ARG A NE  1 
ATOM 7067 C CZ  . ARG A 1 1001 ? 81.735  100.171 89.367  1.00 180.94 ? 1001 ARG A CZ  1 
ATOM 7068 N NH1 . ARG A 1 1001 ? 80.952  100.810 90.219  1.00 194.13 ? 1001 ARG A NH1 1 
ATOM 7069 N NH2 . ARG A 1 1001 ? 81.398  98.964  88.947  1.00 175.89 ? 1001 ARG A NH2 1 
ATOM 7070 N N   . LEU A 1 1002 ? 88.152  97.002  86.958  1.00 54.65  ? 1002 LEU A N   1 
ATOM 7071 C CA  . LEU A 1 1002 ? 89.032  96.640  85.859  1.00 46.98  ? 1002 LEU A CA  1 
ATOM 7072 C C   . LEU A 1 1002 ? 89.290  95.138  85.887  1.00 50.77  ? 1002 LEU A C   1 
ATOM 7073 O O   . LEU A 1 1002 ? 89.087  94.466  84.886  1.00 53.12  ? 1002 LEU A O   1 
ATOM 7074 C CB  . LEU A 1 1002 ? 90.343  97.416  85.980  1.00 38.93  ? 1002 LEU A CB  1 
ATOM 7075 C CG  . LEU A 1 1002 ? 90.194  98.927  85.864  1.00 41.91  ? 1002 LEU A CG  1 
ATOM 7076 C CD1 . LEU A 1 1002 ? 91.220  99.623  86.742  1.00 43.71  ? 1002 LEU A CD1 1 
ATOM 7077 C CD2 . LEU A 1 1002 ? 90.312  99.397  84.419  1.00 44.23  ? 1002 LEU A CD2 1 
ATOM 7078 N N   . TRP A 1 1003 ? 89.742  94.633  87.038  1.00 51.29  ? 1003 TRP A N   1 
ATOM 7079 C CA  . TRP A 1 1003 ? 90.137  93.238  87.174  1.00 48.69  ? 1003 TRP A CA  1 
ATOM 7080 C C   . TRP A 1 1003 ? 88.983  92.348  86.756  1.00 45.33  ? 1003 TRP A C   1 
ATOM 7081 O O   . TRP A 1 1003 ? 89.208  91.292  86.171  1.00 51.49  ? 1003 TRP A O   1 
ATOM 7082 C CB  . TRP A 1 1003 ? 90.563  92.880  88.610  1.00 49.65  ? 1003 TRP A CB  1 
ATOM 7083 C CG  . TRP A 1 1003 ? 91.966  93.208  88.999  1.00 45.40  ? 1003 TRP A CG  1 
ATOM 7084 C CD1 . TRP A 1 1003 ? 93.032  93.398  88.178  1.00 52.02  ? 1003 TRP A CD1 1 
ATOM 7085 C CD2 . TRP A 1 1003 ? 92.442  93.437  90.330  1.00 42.79  ? 1003 TRP A CD2 1 
ATOM 7086 N NE1 . TRP A 1 1003 ? 94.149  93.700  88.907  1.00 55.79  ? 1003 TRP A NE1 1 
ATOM 7087 C CE2 . TRP A 1 1003 ? 93.816  93.734  90.234  1.00 49.27  ? 1003 TRP A CE2 1 
ATOM 7088 C CE3 . TRP A 1 1003 ? 91.852  93.398  91.591  1.00 47.18  ? 1003 TRP A CE3 1 
ATOM 7089 C CZ2 . TRP A 1 1003 ? 94.618  93.989  91.346  1.00 51.53  ? 1003 TRP A CZ2 1 
ATOM 7090 C CZ3 . TRP A 1 1003 ? 92.641  93.655  92.695  1.00 56.46  ? 1003 TRP A CZ3 1 
ATOM 7091 C CH2 . TRP A 1 1003 ? 94.005  93.952  92.575  1.00 54.70  ? 1003 TRP A CH2 1 
ATOM 7092 N N   . LEU A 1 1004 ? 87.764  92.733  87.124  1.00 45.37  ? 1004 LEU A N   1 
ATOM 7093 C CA  . LEU A 1 1004 ? 86.665  91.841  86.843  1.00 58.01  ? 1004 LEU A CA  1 
ATOM 7094 C C   . LEU A 1 1004 ? 86.620  91.608  85.341  1.00 67.75  ? 1004 LEU A C   1 
ATOM 7095 O O   . LEU A 1 1004 ? 86.361  90.498  84.903  1.00 80.80  ? 1004 LEU A O   1 
ATOM 7096 C CB  . LEU A 1 1004 ? 85.346  92.391  87.376  1.00 67.50  ? 1004 LEU A CB  1 
ATOM 7097 C CG  . LEU A 1 1004 ? 84.283  91.315  87.613  1.00 77.38  ? 1004 LEU A CG  1 
ATOM 7098 C CD1 . LEU A 1 1004 ? 83.106  91.880  88.394  1.00 84.49  ? 1004 LEU A CD1 1 
ATOM 7099 C CD2 . LEU A 1 1004 ? 83.819  90.694  86.299  1.00 76.48  ? 1004 LEU A CD2 1 
ATOM 7100 N N   . CYS A 1 1005 ? 86.974  92.614  84.544  1.00 73.73  ? 1005 CYS A N   1 
ATOM 7101 C CA  . CYS A 1 1005 ? 86.834  92.456  83.105  1.00 81.56  ? 1005 CYS A CA  1 
ATOM 7102 C C   . CYS A 1 1005 ? 88.192  92.377  82.407  1.00 73.39  ? 1005 CYS A C   1 
ATOM 7103 O O   . CYS A 1 1005 ? 88.413  93.079  81.430  1.00 75.16  ? 1005 CYS A O   1 
ATOM 7104 C CB  . CYS A 1 1005 ? 86.005  93.592  82.518  1.00 97.41  ? 1005 CYS A CB  1 
ATOM 7105 S SG  . CYS A 1 1005 ? 86.878  95.177  82.462  1.00 125.01 ? 1005 CYS A SG  1 
ATOM 7106 N N   . GLY A 1 1006 ? 89.097  91.531  82.909  1.00 67.28  ? 1006 GLY A N   1 
ATOM 7107 C CA  . GLY A 1 1006 ? 90.192  91.002  82.114  1.00 64.52  ? 1006 GLY A CA  1 
ATOM 7108 C C   . GLY A 1 1006 ? 91.519  91.743  82.246  1.00 55.90  ? 1006 GLY A C   1 
ATOM 7109 O O   . GLY A 1 1006 ? 92.499  91.328  81.639  1.00 60.57  ? 1006 GLY A O   1 
ATOM 7110 N N   . SER A 1 1007 ? 91.590  92.819  83.017  1.00 55.93  ? 1007 SER A N   1 
ATOM 7111 C CA  . SER A 1 1007 ? 92.796  93.627  82.953  1.00 70.87  ? 1007 SER A CA  1 
ATOM 7112 C C   . SER A 1 1007 ? 93.970  92.905  83.602  1.00 59.10  ? 1007 SER A C   1 
ATOM 7113 O O   . SER A 1 1007 ? 94.160  92.962  84.808  1.00 60.97  ? 1007 SER A O   1 
ATOM 7114 C CB  . SER A 1 1007 ? 92.586  94.987  83.536  1.00 90.95  ? 1007 SER A CB  1 
ATOM 7115 O OG  . SER A 1 1007 ? 91.544  95.665  82.842  1.00 99.41  ? 1007 SER A OG  1 
ATOM 7116 N N   . GLN A 1 1008 ? 94.777  92.267  82.764  1.00 54.34  ? 1008 GLN A N   1 
ATOM 7117 C CA  . GLN A 1 1008 ? 95.901  91.497  83.236  1.00 56.45  ? 1008 GLN A CA  1 
ATOM 7118 C C   . GLN A 1 1008 ? 96.633  92.291  84.303  1.00 49.33  ? 1008 GLN A C   1 
ATOM 7119 O O   . GLN A 1 1008 ? 97.009  91.728  85.328  1.00 65.53  ? 1008 GLN A O   1 
ATOM 7120 C CB  . GLN A 1 1008 ? 96.840  91.121  82.092  1.00 68.37  ? 1008 GLN A CB  1 
ATOM 7121 C CG  . GLN A 1 1008 ? 96.236  90.086  81.155  1.00 78.88  ? 1008 GLN A CG  1 
ATOM 7122 C CD  . GLN A 1 1008 ? 95.217  90.678  80.214  1.00 94.11  ? 1008 GLN A CD  1 
ATOM 7123 O OE1 . GLN A 1 1008 ? 95.039  91.894  80.139  1.00 107.09 ? 1008 GLN A OE1 1 
ATOM 7124 N NE2 . GLN A 1 1008 ? 94.533  89.813  79.485  1.00 96.68  ? 1008 GLN A NE2 1 
ATOM 7125 N N   . MET A 1 1009 ? 96.796  93.587  84.088  1.00 43.43  ? 1009 MET A N   1 
ATOM 7126 C CA  . MET A 1 1009 ? 97.670  94.349  84.957  1.00 53.10  ? 1009 MET A CA  1 
ATOM 7127 C C   . MET A 1 1009 ? 96.997  95.651  85.382  1.00 58.36  ? 1009 MET A C   1 
ATOM 7128 O O   . MET A 1 1009 ? 96.736  96.509  84.543  1.00 74.19  ? 1009 MET A O   1 
ATOM 7129 C CB  . MET A 1 1009 ? 98.956  94.712  84.216  1.00 56.80  ? 1009 MET A CB  1 
ATOM 7130 C CG  . MET A 1 1009 ? 100.012 93.653  84.228  1.00 59.14  ? 1009 MET A CG  1 
ATOM 7131 S SD  . MET A 1 1009 ? 101.438 94.297  83.336  1.00 76.21  ? 1009 MET A SD  1 
ATOM 7132 C CE  . MET A 1 1009 ? 102.110 92.781  82.669  1.00 81.49  ? 1009 MET A CE  1 
ATOM 7133 N N   . VAL A 1 1010 ? 96.732  95.801  86.681  1.00 47.64  ? 1010 VAL A N   1 
ATOM 7134 C CA  . VAL A 1 1010 ? 96.300  97.076  87.216  1.00 39.51  ? 1010 VAL A CA  1 
ATOM 7135 C C   . VAL A 1 1010 ? 97.413  97.597  88.093  1.00 32.93  ? 1010 VAL A C   1 
ATOM 7136 O O   . VAL A 1 1010 ? 97.752  96.934  89.061  1.00 39.83  ? 1010 VAL A O   1 
ATOM 7137 C CB  . VAL A 1 1010 ? 95.012  96.919  88.038  1.00 46.03  ? 1010 VAL A CB  1 
ATOM 7138 C CG1 . VAL A 1 1010 ? 94.652  98.227  88.725  1.00 53.08  ? 1010 VAL A CG1 1 
ATOM 7139 C CG2 . VAL A 1 1010 ? 93.851  96.408  87.187  1.00 47.31  ? 1010 VAL A CG2 1 
ATOM 7140 N N   . ALA A 1 1011 ? 97.962  98.764  87.792  1.00 32.29  ? 1011 ALA A N   1 
ATOM 7141 C CA  . ALA A 1 1011 ? 99.090  99.253  88.573  1.00 39.87  ? 1011 ALA A CA  1 
ATOM 7142 C C   . ALA A 1 1011 ? 98.611  100.199 89.669  1.00 41.44  ? 1011 ALA A C   1 
ATOM 7143 O O   . ALA A 1 1011 ? 98.163  101.297 89.372  1.00 47.44  ? 1011 ALA A O   1 
ATOM 7144 C CB  . ALA A 1 1011 ? 100.084 99.943  87.674  1.00 42.64  ? 1011 ALA A CB  1 
ATOM 7145 N N   . LEU A 1 1012 ? 98.720  99.776  90.934  1.00 40.86  ? 1012 LEU A N   1 
ATOM 7146 C CA  . LEU A 1 1012 ? 98.309  100.600 92.059  1.00 40.12  ? 1012 LEU A CA  1 
ATOM 7147 C C   . LEU A 1 1012 ? 99.560  101.051 92.787  1.00 37.36  ? 1012 LEU A C   1 
ATOM 7148 O O   . LEU A 1 1012 ? 100.377 100.210 93.115  1.00 38.27  ? 1012 LEU A O   1 
ATOM 7149 C CB  . LEU A 1 1012 ? 97.423  99.779  92.996  1.00 44.62  ? 1012 LEU A CB  1 
ATOM 7150 C CG  . LEU A 1 1012 ? 96.142  99.217  92.377  1.00 56.88  ? 1012 LEU A CG  1 
ATOM 7151 C CD1 . LEU A 1 1012 ? 96.430  97.933  91.607  1.00 63.16  ? 1012 LEU A CD1 1 
ATOM 7152 C CD2 . LEU A 1 1012 ? 95.073  98.961  93.436  1.00 62.66  ? 1012 LEU A CD2 1 
ATOM 7153 N N   . ASN A 1 1013 ? 99.731  102.354 93.022  1.00 40.15  ? 1013 ASN A N   1 
ATOM 7154 C CA  . ASN A 1 1013 ? 100.928 102.800 93.712  1.00 46.88  ? 1013 ASN A CA  1 
ATOM 7155 C C   . ASN A 1 1013 ? 101.047 101.956 94.973  1.00 51.40  ? 1013 ASN A C   1 
ATOM 7156 O O   . ASN A 1 1013 ? 100.042 101.724 95.628  1.00 53.34  ? 1013 ASN A O   1 
ATOM 7157 C CB  . ASN A 1 1013 ? 100.911 104.292 94.034  1.00 53.98  ? 1013 ASN A CB  1 
ATOM 7158 C CG  . ASN A 1 1013 ? 100.799 105.167 92.806  1.00 71.26  ? 1013 ASN A CG  1 
ATOM 7159 O OD1 . ASN A 1 1013 ? 99.804  105.105 92.079  1.00 80.45  ? 1013 ASN A OD1 1 
ATOM 7160 N ND2 . ASN A 1 1013 ? 101.809 105.995 92.579  1.00 78.11  ? 1013 ASN A ND2 1 
ATOM 7161 N N   . PHE A 1 1014 ? 102.250 101.444 95.268  1.00 53.00  ? 1014 PHE A N   1 
ATOM 7162 C CA  . PHE A 1 1014 ? 102.435 100.496 96.357  1.00 49.02  ? 1014 PHE A CA  1 
ATOM 7163 C C   . PHE A 1 1014 ? 102.962 101.174 97.615  1.00 48.51  ? 1014 PHE A C   1 
ATOM 7164 O O   . PHE A 1 1014 ? 102.943 100.564 98.679  1.00 55.65  ? 1014 PHE A O   1 
ATOM 7165 C CB  . PHE A 1 1014 ? 103.406 99.385  95.956  1.00 51.33  ? 1014 PHE A CB  1 
ATOM 7166 C CG  . PHE A 1 1014 ? 102.785 98.088  95.511  1.00 50.78  ? 1014 PHE A CG  1 
ATOM 7167 C CD1 . PHE A 1 1014 ? 101.430 97.969  95.253  1.00 54.27  ? 1014 PHE A CD1 1 
ATOM 7168 C CD2 . PHE A 1 1014 ? 103.577 96.967  95.377  1.00 53.43  ? 1014 PHE A CD2 1 
ATOM 7169 C CE1 . PHE A 1 1014 ? 100.888 96.755  94.856  1.00 57.00  ? 1014 PHE A CE1 1 
ATOM 7170 C CE2 . PHE A 1 1014 ? 103.031 95.753  95.001  1.00 56.83  ? 1014 PHE A CE2 1 
ATOM 7171 C CZ  . PHE A 1 1014 ? 101.689 95.648  94.736  1.00 56.76  ? 1014 PHE A CZ  1 
ATOM 7172 N N   . GLN A 1 1015 ? 103.439 102.413 97.487  1.00 47.36  ? 1015 GLN A N   1 
ATOM 7173 C CA  . GLN A 1 1015 ? 103.933 103.167 98.623  1.00 52.35  ? 1015 GLN A CA  1 
ATOM 7174 C C   . GLN A 1 1015 ? 102.772 103.808 99.382  1.00 50.89  ? 1015 GLN A C   1 
ATOM 7175 O O   . GLN A 1 1015 ? 102.983 104.747 100.141 1.00 56.41  ? 1015 GLN A O   1 
ATOM 7176 C CB  . GLN A 1 1015 ? 104.969 104.203 98.162  1.00 62.55  ? 1015 GLN A CB  1 
ATOM 7177 C CG  . GLN A 1 1015 ? 104.441 105.253 97.182  1.00 69.85  ? 1015 GLN A CG  1 
ATOM 7178 C CD  . GLN A 1 1015 ? 104.185 104.704 95.802  1.00 84.89  ? 1015 GLN A CD  1 
ATOM 7179 O OE1 . GLN A 1 1015 ? 103.365 103.812 95.616  1.00 82.09  ? 1015 GLN A OE1 1 
ATOM 7180 N NE2 . GLN A 1 1015 ? 104.892 105.228 94.814  1.00 97.67  ? 1015 GLN A NE2 1 
ATOM 7181 N N   . THR A 1 1016 ? 101.549 103.308 99.188  1.00 50.43  ? 1016 THR A N   1 
ATOM 7182 C CA  . THR A 1 1016 ? 100.372 103.912 99.784  1.00 55.69  ? 1016 THR A CA  1 
ATOM 7183 C C   . THR A 1 1016 ? 99.666  102.879 100.644 1.00 52.51  ? 1016 THR A C   1 
ATOM 7184 O O   . THR A 1 1016 ? 99.751  101.689 100.376 1.00 58.72  ? 1016 THR A O   1 
ATOM 7185 C CB  . THR A 1 1016 ? 99.404  104.443 98.721  1.00 69.17  ? 1016 THR A CB  1 
ATOM 7186 O OG1 . THR A 1 1016 ? 100.126 105.326 97.856  1.00 75.00  ? 1016 THR A OG1 1 
ATOM 7187 C CG2 . THR A 1 1016 ? 98.216  105.172 99.315  1.00 79.83  ? 1016 THR A CG2 1 
ATOM 7188 N N   . ALA A 1 1017 ? 98.969  103.354 101.674 1.00 50.49  ? 1017 ALA A N   1 
ATOM 7189 C CA  . ALA A 1 1017 ? 98.343  102.481 102.645 1.00 52.72  ? 1017 ALA A CA  1 
ATOM 7190 C C   . ALA A 1 1017 ? 96.856  102.307 102.355 1.00 49.32  ? 1017 ALA A C   1 
ATOM 7191 O O   . ALA A 1 1017 ? 96.155  101.658 103.121 1.00 52.84  ? 1017 ALA A O   1 
ATOM 7192 C CB  . ALA A 1 1017 ? 98.569  103.062 104.022 1.00 59.27  ? 1017 ALA A CB  1 
ATOM 7193 N N   . ASP A 1 1018 ? 96.379  102.884 101.254 1.00 52.42  ? 1018 ASP A N   1 
ATOM 7194 C CA  . ASP A 1 1018 ? 94.949  103.028 101.029 1.00 65.61  ? 1018 ASP A CA  1 
ATOM 7195 C C   . ASP A 1 1018 ? 94.262  101.667 100.998 1.00 50.83  ? 1018 ASP A C   1 
ATOM 7196 O O   . ASP A 1 1018 ? 94.914  100.650 100.833 1.00 48.54  ? 1018 ASP A O   1 
ATOM 7197 C CB  . ASP A 1 1018 ? 94.657  103.791 99.730  1.00 96.57  ? 1018 ASP A CB  1 
ATOM 7198 C CG  . ASP A 1 1018 ? 95.239  103.182 98.460  1.00 115.91 ? 1018 ASP A CG  1 
ATOM 7199 O OD1 . ASP A 1 1018 ? 94.917  102.005 98.157  1.00 122.82 ? 1018 ASP A OD1 1 
ATOM 7200 O OD2 . ASP A 1 1018 ? 95.992  103.908 97.762  1.00 124.37 ? 1018 ASP A OD2 1 
ATOM 7201 N N   . LYS A 1 1019 ? 92.929  101.679 101.100 1.00 49.97  ? 1019 LYS A N   1 
ATOM 7202 C CA  . LYS A 1 1019 ? 92.141  100.463 101.010 1.00 50.94  ? 1019 LYS A CA  1 
ATOM 7203 C C   . LYS A 1 1019 ? 92.509  99.710  99.743  1.00 52.29  ? 1019 LYS A C   1 
ATOM 7204 O O   . LYS A 1 1019 ? 92.623  98.484  99.762  1.00 63.56  ? 1019 LYS A O   1 
ATOM 7205 C CB  . LYS A 1 1019 ? 90.633  100.727 100.937 1.00 52.49  ? 1019 LYS A CB  1 
ATOM 7206 C CG  . LYS A 1 1019 ? 89.821  99.536  100.441 1.00 52.09  ? 1019 LYS A CG  1 
ATOM 7207 C CD  . LYS A 1 1019 ? 88.348  99.626  100.710 1.00 58.71  ? 1019 LYS A CD  1 
ATOM 7208 C CE  . LYS A 1 1019 ? 87.612  100.501 99.718  1.00 63.13  ? 1019 LYS A CE  1 
ATOM 7209 N NZ  . LYS A 1 1019 ? 86.159  100.191 99.681  1.00 66.50  ? 1019 LYS A NZ  1 
ATOM 7210 N N   . TYR A 1 1020 ? 92.675  100.438 98.641  1.00 49.47  ? 1020 TYR A N   1 
ATOM 7211 C CA  . TYR A 1 1020 ? 92.763  99.771  97.359  1.00 50.31  ? 1020 TYR A CA  1 
ATOM 7212 C C   . TYR A 1 1020 ? 94.060  98.967  97.267  1.00 50.91  ? 1020 TYR A C   1 
ATOM 7213 O O   . TYR A 1 1020 ? 94.009  97.816  96.837  1.00 54.71  ? 1020 TYR A O   1 
ATOM 7214 C CB  . TYR A 1 1020 ? 92.437  100.763 96.243  1.00 51.98  ? 1020 TYR A CB  1 
ATOM 7215 C CG  . TYR A 1 1020 ? 90.965  101.083 96.234  1.00 59.68  ? 1020 TYR A CG  1 
ATOM 7216 C CD1 . TYR A 1 1020 ? 90.028  100.059 96.255  1.00 67.46  ? 1020 TYR A CD1 1 
ATOM 7217 C CD2 . TYR A 1 1020 ? 90.498  102.384 96.296  1.00 64.84  ? 1020 TYR A CD2 1 
ATOM 7218 C CE1 . TYR A 1 1020 ? 88.667  100.314 96.277  1.00 72.31  ? 1020 TYR A CE1 1 
ATOM 7219 C CE2 . TYR A 1 1020 ? 89.139  102.659 96.318  1.00 72.62  ? 1020 TYR A CE2 1 
ATOM 7220 C CZ  . TYR A 1 1020 ? 88.218  101.622 96.313  1.00 75.97  ? 1020 TYR A CZ  1 
ATOM 7221 O OH  . TYR A 1 1020 ? 86.863  101.871 96.343  1.00 77.74  ? 1020 TYR A OH  1 
ATOM 7222 N N   . MET A 1 1021 ? 95.188  99.511  97.739  1.00 45.45  ? 1021 MET A N   1 
ATOM 7223 C CA  . MET A 1 1021 ? 96.433  98.756  97.720  1.00 40.43  ? 1021 MET A CA  1 
ATOM 7224 C C   . MET A 1 1021 ? 96.283  97.494  98.552  1.00 37.86  ? 1021 MET A C   1 
ATOM 7225 O O   . MET A 1 1021 ? 96.743  96.436  98.158  1.00 49.00  ? 1021 MET A O   1 
ATOM 7226 C CB  . MET A 1 1021 ? 97.597  99.573  98.266  1.00 45.97  ? 1021 MET A CB  1 
ATOM 7227 C CG  . MET A 1 1021 ? 98.861  99.492  97.414  1.00 54.09  ? 1021 MET A CG  1 
ATOM 7228 S SD  . MET A 1 1021 ? 100.125 98.317  97.967  1.00 79.00  ? 1021 MET A SD  1 
ATOM 7229 C CE  . MET A 1 1021 ? 99.589  97.964  99.644  1.00 100.76 ? 1021 MET A CE  1 
ATOM 7230 N N   . GLN A 1 1022 ? 95.589  97.599  99.671  1.00 37.51  ? 1022 GLN A N   1 
ATOM 7231 C CA  . GLN A 1 1022 ? 95.372  96.457  100.542 1.00 41.98  ? 1022 GLN A CA  1 
ATOM 7232 C C   . GLN A 1 1022 ? 94.547  95.389  99.833  1.00 36.68  ? 1022 GLN A C   1 
ATOM 7233 O O   . GLN A 1 1022 ? 94.807  94.207  100.024 1.00 39.72  ? 1022 GLN A O   1 
ATOM 7234 C CB  . GLN A 1 1022 ? 94.707  96.884  101.856 1.00 48.96  ? 1022 GLN A CB  1 
ATOM 7235 C CG  . GLN A 1 1022 ? 95.554  97.898  102.615 1.00 51.48  ? 1022 GLN A CG  1 
ATOM 7236 C CD  . GLN A 1 1022 ? 94.814  98.536  103.760 1.00 45.30  ? 1022 GLN A CD  1 
ATOM 7237 O OE1 . GLN A 1 1022 ? 93.643  98.252  103.992 1.00 38.16  ? 1022 GLN A OE1 1 
ATOM 7238 N NE2 . GLN A 1 1022 ? 95.510  99.398  104.483 1.00 45.83  ? 1022 GLN A NE2 1 
ATOM 7239 N N   . MET A 1 1023 ? 93.575  95.773  99.009  1.00 34.47  ? 1023 MET A N   1 
ATOM 7240 C CA  . MET A 1 1023 ? 92.842  94.746  98.299  1.00 39.49  ? 1023 MET A CA  1 
ATOM 7241 C C   . MET A 1 1023 ? 93.795  94.032  97.348  1.00 46.15  ? 1023 MET A C   1 
ATOM 7242 O O   . MET A 1 1023 ? 93.654  92.838  97.141  1.00 54.93  ? 1023 MET A O   1 
ATOM 7243 C CB  . MET A 1 1023 ? 91.667  95.298  97.504  1.00 45.40  ? 1023 MET A CB  1 
ATOM 7244 C CG  . MET A 1 1023 ? 90.458  95.484  98.353  1.00 56.37  ? 1023 MET A CG  1 
ATOM 7245 S SD  . MET A 1 1023 ? 88.930  95.364  97.402  1.00 92.01  ? 1023 MET A SD  1 
ATOM 7246 C CE  . MET A 1 1023 ? 89.438  95.789  95.732  1.00 95.73  ? 1023 MET A CE  1 
ATOM 7247 N N   . ASN A 1 1024 ? 94.783  94.748  96.801  1.00 48.97  ? 1024 ASN A N   1 
ATOM 7248 C CA  . ASN A 1 1024 ? 95.779  94.154  95.921  1.00 48.74  ? 1024 ASN A CA  1 
ATOM 7249 C C   . ASN A 1 1024 ? 96.595  93.099  96.651  1.00 47.92  ? 1024 ASN A C   1 
ATOM 7250 O O   . ASN A 1 1024 ? 96.863  92.040  96.095  1.00 62.31  ? 1024 ASN A O   1 
ATOM 7251 C CB  . ASN A 1 1024 ? 96.786  95.174  95.397  1.00 58.56  ? 1024 ASN A CB  1 
ATOM 7252 C CG  . ASN A 1 1024 ? 97.564  94.650  94.211  1.00 69.39  ? 1024 ASN A CG  1 
ATOM 7253 O OD1 . ASN A 1 1024 ? 96.998  94.519  93.127  1.00 78.00  ? 1024 ASN A OD1 1 
ATOM 7254 N ND2 . ASN A 1 1024 ? 98.850  94.372  94.396  1.00 67.49  ? 1024 ASN A ND2 1 
ATOM 7255 N N   . HIS A 1 1025 ? 97.042  93.410  97.871  1.00 45.27  ? 1025 HIS A N   1 
ATOM 7256 C CA  . HIS A 1 1025 ? 97.865  92.483  98.629  1.00 43.55  ? 1025 HIS A CA  1 
ATOM 7257 C C   . HIS A 1 1025 ? 97.090  91.213  98.941  1.00 36.50  ? 1025 HIS A C   1 
ATOM 7258 O O   . HIS A 1 1025 ? 97.703  90.186  99.177  1.00 38.57  ? 1025 HIS A O   1 
ATOM 7259 C CB  . HIS A 1 1025 ? 98.412  93.102  99.913  1.00 50.45  ? 1025 HIS A CB  1 
ATOM 7260 C CG  . HIS A 1 1025 ? 99.741  93.728  99.707  1.00 65.62  ? 1025 HIS A CG  1 
ATOM 7261 N ND1 . HIS A 1 1025 ? 100.294 93.859  98.454  1.00 78.71  ? 1025 HIS A ND1 1 
ATOM 7262 C CD2 . HIS A 1 1025 ? 100.633 94.239  100.567 1.00 84.09  ? 1025 HIS A CD2 1 
ATOM 7263 C CE1 . HIS A 1 1025 ? 101.486 94.426  98.561  1.00 91.99  ? 1025 HIS A CE1 1 
ATOM 7264 N NE2 . HIS A 1 1025 ? 101.709 94.674  99.836  1.00 86.71  ? 1025 HIS A NE2 1 
ATOM 7265 N N   . ALA A 1 1026 ? 95.761  91.284  98.880  1.00 33.14  ? 1026 ALA A N   1 
ATOM 7266 C CA  . ALA A 1 1026 ? 94.925  90.112  99.045  1.00 36.79  ? 1026 ALA A CA  1 
ATOM 7267 C C   . ALA A 1 1026 ? 94.932  89.235  97.793  1.00 41.28  ? 1026 ALA A C   1 
ATOM 7268 O O   . ALA A 1 1026 ? 95.205  88.037  97.887  1.00 49.98  ? 1026 ALA A O   1 
ATOM 7269 C CB  . ALA A 1 1026 ? 93.523  90.517  99.404  1.00 37.39  ? 1026 ALA A CB  1 
ATOM 7270 N N   . LEU A 1 1027 ? 94.576  89.789  96.630  1.00 39.92  ? 1027 LEU A N   1 
ATOM 7271 C CA  . LEU A 1 1027 ? 94.416  88.925  95.478  1.00 41.29  ? 1027 LEU A CA  1 
ATOM 7272 C C   . LEU A 1 1027 ? 95.731  88.204  95.242  1.00 41.25  ? 1027 LEU A C   1 
ATOM 7273 O O   . LEU A 1 1027 ? 95.732  87.024  94.896  1.00 46.97  ? 1027 LEU A O   1 
ATOM 7274 C CB  . LEU A 1 1027 ? 93.967  89.697  94.238  1.00 47.88  ? 1027 LEU A CB  1 
ATOM 7275 C CG  . LEU A 1 1027 ? 93.161  88.865  93.235  1.00 59.72  ? 1027 LEU A CG  1 
ATOM 7276 C CD1 . LEU A 1 1027 ? 92.163  87.947  93.948  1.00 63.40  ? 1027 LEU A CD1 1 
ATOM 7277 C CD2 . LEU A 1 1027 ? 92.414  89.751  92.243  1.00 67.11  ? 1027 LEU A CD2 1 
ATOM 7278 N N   . PHE A 1 1028 ? 96.844  88.873  95.542  1.00 42.53  ? 1028 PHE A N   1 
ATOM 7279 C CA  . PHE A 1 1028 ? 98.127  88.290  95.202  1.00 54.06  ? 1028 PHE A CA  1 
ATOM 7280 C C   . PHE A 1 1028 ? 98.565  87.224  96.205  1.00 60.07  ? 1028 PHE A C   1 
ATOM 7281 O O   . PHE A 1 1028 ? 99.241  86.286  95.786  1.00 72.68  ? 1028 PHE A O   1 
ATOM 7282 C CB  . PHE A 1 1028 ? 99.103  89.400  94.822  1.00 56.51  ? 1028 PHE A CB  1 
ATOM 7283 C CG  . PHE A 1 1028 ? 98.609  90.058  93.560  1.00 59.71  ? 1028 PHE A CG  1 
ATOM 7284 C CD1 . PHE A 1 1028 ? 97.985  89.297  92.585  1.00 55.38  ? 1028 PHE A CD1 1 
ATOM 7285 C CD2 . PHE A 1 1028 ? 98.689  91.424  93.374  1.00 73.21  ? 1028 PHE A CD2 1 
ATOM 7286 C CE1 . PHE A 1 1028 ? 97.485  89.879  91.442  1.00 59.71  ? 1028 PHE A CE1 1 
ATOM 7287 C CE2 . PHE A 1 1028 ? 98.181  92.007  92.225  1.00 78.90  ? 1028 PHE A CE2 1 
ATOM 7288 C CZ  . PHE A 1 1028 ? 97.584  91.233  91.260  1.00 72.08  ? 1028 PHE A CZ  1 
ATOM 7289 N N   . SER A 1 1029 ? 98.113  87.270  97.463  1.00 50.74  ? 1029 SER A N   1 
ATOM 7290 C CA  . SER A 1 1029 ? 98.393  86.149  98.352  1.00 47.39  ? 1029 SER A CA  1 
ATOM 7291 C C   . SER A 1 1029 ? 97.847  84.848  97.768  1.00 40.51  ? 1029 SER A C   1 
ATOM 7292 O O   . SER A 1 1029 ? 98.557  83.843  97.683  1.00 40.31  ? 1029 SER A O   1 
ATOM 7293 C CB  . SER A 1 1029 ? 97.860  86.363  99.737  1.00 54.85  ? 1029 SER A CB  1 
ATOM 7294 O OG  . SER A 1 1029 ? 98.822  87.049  100.536 1.00 60.66  ? 1029 SER A OG  1 
ATOM 7295 N N   . LEU A 1 1030 ? 96.578  84.889  97.369  1.00 36.14  ? 1030 LEU A N   1 
ATOM 7296 C CA  . LEU A 1 1030 ? 95.958  83.744  96.737  1.00 37.53  ? 1030 LEU A CA  1 
ATOM 7297 C C   . LEU A 1 1030 ? 96.936  83.189  95.697  1.00 45.17  ? 1030 LEU A C   1 
ATOM 7298 O O   . LEU A 1 1030 ? 97.506  83.965  94.924  1.00 44.66  ? 1030 LEU A O   1 
ATOM 7299 C CB  . LEU A 1 1030 ? 94.646  84.226  96.119  1.00 38.27  ? 1030 LEU A CB  1 
ATOM 7300 C CG  . LEU A 1 1030 ? 93.495  83.228  96.160  1.00 46.05  ? 1030 LEU A CG  1 
ATOM 7301 C CD1 . LEU A 1 1030 ? 92.203  83.858  95.655  1.00 49.89  ? 1030 LEU A CD1 1 
ATOM 7302 C CD2 . LEU A 1 1030 ? 93.823  81.999  95.333  1.00 51.01  ? 1030 LEU A CD2 1 
ATOM 7303 N N   . ASN A 1 1031 ? 97.153  81.855  95.724  1.00 53.18  ? 1031 ASN A N   1 
ATOM 7304 C CA  . ASN A 1 1031 ? 98.074  81.118  94.848  1.00 58.90  ? 1031 ASN A CA  1 
ATOM 7305 C C   . ASN A 1 1031 ? 99.522  81.570  95.043  1.00 46.80  ? 1031 ASN A C   1 
ATOM 7306 O O   . ASN A 1 1031 ? 100.255 81.766  94.071  1.00 41.51  ? 1031 ASN A O   1 
ATOM 7307 C CB  . ASN A 1 1031 ? 97.722  81.184  93.351  1.00 71.43  ? 1031 ASN A CB  1 
ATOM 7308 C CG  . ASN A 1 1031 ? 96.564  80.290  92.952  1.00 90.51  ? 1031 ASN A CG  1 
ATOM 7309 O OD1 . ASN A 1 1031 ? 96.171  80.265  91.787  1.00 101.21 ? 1031 ASN A OD1 1 
ATOM 7310 N ND2 . ASN A 1 1031 ? 96.022  79.548  93.905  1.00 98.40  ? 1031 ASN A ND2 1 
ATOM 7311 N N   . GLY A 1 1032 ? 99.936  81.677  96.304  1.00 40.88  ? 1032 GLY A N   1 
ATOM 7312 C CA  . GLY A 1 1032 ? 101.330 81.914  96.612  1.00 40.53  ? 1032 GLY A CA  1 
ATOM 7313 C C   . GLY A 1 1032 ? 101.667 83.390  96.483  1.00 47.79  ? 1032 GLY A C   1 
ATOM 7314 O O   . GLY A 1 1032 ? 100.820 84.211  96.144  1.00 50.64  ? 1032 GLY A O   1 
ATOM 7315 N N   . ARG A 1 1033 ? 102.921 83.721  96.784  1.00 61.80  ? 1033 ARG A N   1 
ATOM 7316 C CA  . ARG A 1 1033 ? 103.408 85.081  96.644  1.00 72.67  ? 1033 ARG A CA  1 
ATOM 7317 C C   . ARG A 1 1033 ? 103.946 85.243  95.223  1.00 68.95  ? 1033 ARG A C   1 
ATOM 7318 O O   . ARG A 1 1033 ? 104.533 86.267  94.884  1.00 72.50  ? 1033 ARG A O   1 
ATOM 7319 C CB  . ARG A 1 1033 ? 104.443 85.351  97.743  1.00 89.25  ? 1033 ARG A CB  1 
ATOM 7320 C CG  . ARG A 1 1033 ? 104.552 86.810  98.164  1.00 107.36 ? 1033 ARG A CG  1 
ATOM 7321 C CD  . ARG A 1 1033 ? 104.754 86.970  99.663  1.00 122.25 ? 1033 ARG A CD  1 
ATOM 7322 N NE  . ARG A 1 1033 ? 103.572 86.597  100.434 1.00 131.15 ? 1033 ARG A NE  1 
ATOM 7323 C CZ  . ARG A 1 1033 ? 102.405 87.233  100.395 1.00 135.08 ? 1033 ARG A CZ  1 
ATOM 7324 N NH1 . ARG A 1 1033 ? 102.253 88.297  99.626  1.00 141.05 ? 1033 ARG A NH1 1 
ATOM 7325 N NH2 . ARG A 1 1033 ? 101.395 86.813  101.140 1.00 135.37 ? 1033 ARG A NH2 1 
ATOM 7326 N N   . THR A 1 1034 ? 103.742 84.199  94.409  1.00 63.51  ? 1034 THR A N   1 
ATOM 7327 C CA  . THR A 1 1034 ? 104.035 84.203  92.988  1.00 61.37  ? 1034 THR A CA  1 
ATOM 7328 C C   . THR A 1 1034 ? 103.725 85.545  92.355  1.00 53.74  ? 1034 THR A C   1 
ATOM 7329 O O   . THR A 1 1034 ? 104.578 86.153  91.724  1.00 54.81  ? 1034 THR A O   1 
ATOM 7330 C CB  . THR A 1 1034 ? 103.165 83.175  92.262  1.00 71.86  ? 1034 THR A CB  1 
ATOM 7331 O OG1 . THR A 1 1034 ? 101.838 83.377  92.747  1.00 72.71  ? 1034 THR A OG1 1 
ATOM 7332 C CG2 . THR A 1 1034 ? 103.598 81.750  92.515  1.00 81.96  ? 1034 THR A CG2 1 
ATOM 7333 N N   . GLY A 1 1035 ? 102.476 85.967  92.519  1.00 54.37  ? 1035 GLY A N   1 
ATOM 7334 C CA  . GLY A 1 1035 ? 102.003 87.206  91.937  1.00 55.30  ? 1035 GLY A CA  1 
ATOM 7335 C C   . GLY A 1 1035 ? 101.250 86.980  90.635  1.00 47.21  ? 1035 GLY A C   1 
ATOM 7336 O O   . GLY A 1 1035 ? 101.034 87.911  89.870  1.00 56.14  ? 1035 GLY A O   1 
ATOM 7337 N N   . TYR A 1 1036 ? 100.846 85.743  90.380  1.00 37.81  ? 1036 TYR A N   1 
ATOM 7338 C CA  . TYR A 1 1036 ? 99.896  85.477  89.324  1.00 36.82  ? 1036 TYR A CA  1 
ATOM 7339 C C   . TYR A 1 1036 ? 98.719  84.769  89.961  1.00 33.59  ? 1036 TYR A C   1 
ATOM 7340 O O   . TYR A 1 1036 ? 98.936  83.841  90.731  1.00 48.74  ? 1036 TYR A O   1 
ATOM 7341 C CB  . TYR A 1 1036 ? 100.540 84.596  88.247  1.00 41.08  ? 1036 TYR A CB  1 
ATOM 7342 C CG  . TYR A 1 1036 ? 101.666 85.225  87.461  1.00 43.10  ? 1036 TYR A CG  1 
ATOM 7343 C CD1 . TYR A 1 1036 ? 102.858 85.558  88.075  1.00 45.70  ? 1036 TYR A CD1 1 
ATOM 7344 C CD2 . TYR A 1 1036 ? 101.550 85.483  86.103  1.00 43.27  ? 1036 TYR A CD2 1 
ATOM 7345 C CE1 . TYR A 1 1036 ? 103.895 86.146  87.373  1.00 46.64  ? 1036 TYR A CE1 1 
ATOM 7346 C CE2 . TYR A 1 1036 ? 102.578 86.072  85.387  1.00 45.22  ? 1036 TYR A CE2 1 
ATOM 7347 C CZ  . TYR A 1 1036 ? 103.755 86.411  86.027  1.00 44.70  ? 1036 TYR A CZ  1 
ATOM 7348 O OH  . TYR A 1 1036 ? 104.795 86.981  85.342  1.00 44.09  ? 1036 TYR A OH  1 
ATOM 7349 N N   . VAL A 1 1037 ? 97.502  85.174  89.647  1.00 29.18  ? 1037 VAL A N   1 
ATOM 7350 C CA  . VAL A 1 1037 ? 96.358  84.420  90.106  1.00 34.03  ? 1037 VAL A CA  1 
ATOM 7351 C C   . VAL A 1 1037 ? 95.545  84.095  88.879  1.00 35.32  ? 1037 VAL A C   1 
ATOM 7352 O O   . VAL A 1 1037 ? 95.079  85.006  88.223  1.00 38.07  ? 1037 VAL A O   1 
ATOM 7353 C CB  . VAL A 1 1037 ? 95.495  85.200  91.111  1.00 47.93  ? 1037 VAL A CB  1 
ATOM 7354 C CG1 . VAL A 1 1037 ? 95.001  84.294  92.234  1.00 53.19  ? 1037 VAL A CG1 1 
ATOM 7355 C CG2 . VAL A 1 1037 ? 96.239  86.399  91.691  1.00 58.15  ? 1037 VAL A CG2 1 
ATOM 7356 N N   . LEU A 1 1038 ? 95.407  82.814  88.544  1.00 44.09  ? 1038 LEU A N   1 
ATOM 7357 C CA  . LEU A 1 1038 ? 94.652  82.441  87.358  1.00 48.02  ? 1038 LEU A CA  1 
ATOM 7358 C C   . LEU A 1 1038 ? 93.254  83.024  87.476  1.00 51.00  ? 1038 LEU A C   1 
ATOM 7359 O O   . LEU A 1 1038 ? 92.628  82.931  88.529  1.00 55.68  ? 1038 LEU A O   1 
ATOM 7360 C CB  . LEU A 1 1038 ? 94.559  80.924  87.234  1.00 53.08  ? 1038 LEU A CB  1 
ATOM 7361 C CG  . LEU A 1 1038 ? 93.767  80.427  86.031  1.00 58.69  ? 1038 LEU A CG  1 
ATOM 7362 C CD1 . LEU A 1 1038 ? 94.580  80.587  84.758  1.00 57.31  ? 1038 LEU A CD1 1 
ATOM 7363 C CD2 . LEU A 1 1038 ? 93.330  78.975  86.243  1.00 67.76  ? 1038 LEU A CD2 1 
ATOM 7364 N N   . GLN A 1 1039 ? 92.806  83.668  86.400  1.00 58.55  ? 1039 GLN A N   1 
ATOM 7365 C CA  . GLN A 1 1039 ? 91.490  84.270  86.377  1.00 61.21  ? 1039 GLN A CA  1 
ATOM 7366 C C   . GLN A 1 1039 ? 90.490  83.135  86.499  1.00 48.22  ? 1039 GLN A C   1 
ATOM 7367 O O   . GLN A 1 1039 ? 90.756  82.017  86.076  1.00 47.30  ? 1039 GLN A O   1 
ATOM 7368 C CB  . GLN A 1 1039 ? 91.315  85.092  85.101  1.00 78.07  ? 1039 GLN A CB  1 
ATOM 7369 C CG  . GLN A 1 1039 ? 92.185  86.345  85.057  1.00 90.21  ? 1039 GLN A CG  1 
ATOM 7370 C CD  . GLN A 1 1039 ? 91.987  87.141  83.789  1.00 107.17 ? 1039 GLN A CD  1 
ATOM 7371 O OE1 . GLN A 1 1039 ? 91.165  86.810  82.934  1.00 114.58 ? 1039 GLN A OE1 1 
ATOM 7372 N NE2 . GLN A 1 1039 ? 92.734  88.223  83.659  1.00 112.90 ? 1039 GLN A NE2 1 
ATOM 7373 N N   . PRO A 1 1040 ? 89.319  83.382  87.092  1.00 51.42  ? 1040 PRO A N   1 
ATOM 7374 C CA  . PRO A 1 1040 ? 88.347  82.319  87.306  1.00 61.27  ? 1040 PRO A CA  1 
ATOM 7375 C C   . PRO A 1 1040 ? 87.958  81.740  85.959  1.00 69.34  ? 1040 PRO A C   1 
ATOM 7376 O O   . PRO A 1 1040 ? 87.821  82.485  84.994  1.00 73.28  ? 1040 PRO A O   1 
ATOM 7377 C CB  . PRO A 1 1040 ? 87.144  83.009  87.955  1.00 68.20  ? 1040 PRO A CB  1 
ATOM 7378 C CG  . PRO A 1 1040 ? 87.712  84.320  88.483  1.00 70.57  ? 1040 PRO A CG  1 
ATOM 7379 C CD  . PRO A 1 1040 ? 88.854  84.687  87.556  1.00 58.56  ? 1040 PRO A CD  1 
ATOM 7380 N N   . GLU A 1 1041 ? 87.805  80.416  85.912  1.00 85.57  ? 1041 GLU A N   1 
ATOM 7381 C CA  . GLU A 1 1041 ? 87.534  79.724  84.666  1.00 102.81 ? 1041 GLU A CA  1 
ATOM 7382 C C   . GLU A 1 1041 ? 86.244  80.274  84.061  1.00 100.03 ? 1041 GLU A C   1 
ATOM 7383 O O   . GLU A 1 1041 ? 86.149  80.417  82.846  1.00 108.87 ? 1041 GLU A O   1 
ATOM 7384 C CB  . GLU A 1 1041 ? 87.458  78.213  84.906  1.00 124.79 ? 1041 GLU A CB  1 
ATOM 7385 C CG  . GLU A 1 1041 ? 87.129  77.393  83.666  1.00 146.75 ? 1041 GLU A CG  1 
ATOM 7386 C CD  . GLU A 1 1041 ? 88.139  77.463  82.530  1.00 167.92 ? 1041 GLU A CD  1 
ATOM 7387 O OE1 . GLU A 1 1041 ? 87.883  76.836  81.479  1.00 174.70 ? 1041 GLU A OE1 1 
ATOM 7388 O OE2 . GLU A 1 1041 ? 89.178  78.141  82.695  1.00 176.83 ? 1041 GLU A OE2 1 
ATOM 7389 N N   . SER A 1 1042 ? 85.270  80.585  84.923  1.00 91.87  ? 1042 SER A N   1 
ATOM 7390 C CA  . SER A 1 1042 ? 83.964  81.028  84.473  1.00 91.85  ? 1042 SER A CA  1 
ATOM 7391 C C   . SER A 1 1042 ? 84.075  82.303  83.645  1.00 83.63  ? 1042 SER A C   1 
ATOM 7392 O O   . SER A 1 1042 ? 83.340  82.449  82.678  1.00 82.71  ? 1042 SER A O   1 
ATOM 7393 C CB  . SER A 1 1042 ? 83.031  81.226  85.636  1.00 105.58 ? 1042 SER A CB  1 
ATOM 7394 O OG  . SER A 1 1042 ? 83.506  82.252  86.494  1.00 112.26 ? 1042 SER A OG  1 
ATOM 7395 N N   . MET A 1 1043 ? 84.955  83.237  84.030  1.00 83.60  ? 1043 MET A N   1 
ATOM 7396 C CA  . MET A 1 1043 ? 85.025  84.507  83.321  1.00 84.44  ? 1043 MET A CA  1 
ATOM 7397 C C   . MET A 1 1043 ? 85.277  84.234  81.843  1.00 91.68  ? 1043 MET A C   1 
ATOM 7398 O O   . MET A 1 1043 ? 84.626  84.820  80.985  1.00 98.55  ? 1043 MET A O   1 
ATOM 7399 C CB  . MET A 1 1043 ? 86.134  85.431  83.818  1.00 74.89  ? 1043 MET A CB  1 
ATOM 7400 C CG  . MET A 1 1043 ? 85.813  86.160  85.093  1.00 78.46  ? 1043 MET A CG  1 
ATOM 7401 S SD  . MET A 1 1043 ? 87.062  87.410  85.468  1.00 90.76  ? 1043 MET A SD  1 
ATOM 7402 C CE  . MET A 1 1043 ? 88.509  86.667  84.728  1.00 81.59  ? 1043 MET A CE  1 
ATOM 7403 N N   . ARG A 1 1044 ? 86.250  83.364  81.557  1.00 90.51  ? 1044 ARG A N   1 
ATOM 7404 C CA  . ARG A 1 1044 ? 86.460  82.890  80.198  1.00 85.83  ? 1044 ARG A CA  1 
ATOM 7405 C C   . ARG A 1 1044 ? 85.270  82.004  79.848  1.00 82.68  ? 1044 ARG A C   1 
ATOM 7406 O O   . ARG A 1 1044 ? 84.903  81.181  80.676  1.00 87.46  ? 1044 ARG A O   1 
ATOM 7407 C CB  . ARG A 1 1044 ? 87.775  82.112  80.106  1.00 88.86  ? 1044 ARG A CB  1 
ATOM 7408 C CG  . ARG A 1 1044 ? 88.994  82.860  80.639  1.00 95.99  ? 1044 ARG A CG  1 
ATOM 7409 C CD  . ARG A 1 1044 ? 90.211  81.979  80.862  1.00 102.79 ? 1044 ARG A CD  1 
ATOM 7410 N NE  . ARG A 1 1044 ? 90.569  81.309  79.619  1.00 121.29 ? 1044 ARG A NE  1 
ATOM 7411 C CZ  . ARG A 1 1044 ? 91.565  80.440  79.476  1.00 143.19 ? 1044 ARG A CZ  1 
ATOM 7412 N NH1 . ARG A 1 1044 ? 91.787  79.873  78.303  1.00 152.46 ? 1044 ARG A NH1 1 
ATOM 7413 N NH2 . ARG A 1 1044 ? 92.331  80.145  80.508  1.00 142.79 ? 1044 ARG A NH2 1 
ATOM 7414 N N   . THR A 1 1045 ? 84.661  82.219  78.673  1.00 89.32  ? 1045 THR A N   1 
ATOM 7415 C CA  . THR A 1 1045 ? 83.517  81.456  78.184  1.00 112.23 ? 1045 THR A CA  1 
ATOM 7416 C C   . THR A 1 1045 ? 82.946  82.133  76.945  1.00 141.42 ? 1045 THR A C   1 
ATOM 7417 O O   . THR A 1 1045 ? 83.661  82.822  76.227  1.00 159.43 ? 1045 THR A O   1 
ATOM 7418 C CB  . THR A 1 1045 ? 82.277  81.425  79.090  1.00 121.49 ? 1045 THR A CB  1 
ATOM 7419 O OG1 . THR A 1 1045 ? 81.892  82.785  79.288  1.00 125.58 ? 1045 THR A OG1 1 
ATOM 7420 C CG2 . THR A 1 1045 ? 82.447  80.686  80.397  1.00 129.18 ? 1045 THR A CG2 1 
ATOM 7421 N N   . GLU A 1 1046 ? 81.629  81.971  76.748  1.00 160.74 ? 1046 GLU A N   1 
ATOM 7422 C CA  . GLU A 1 1046 ? 80.922  82.599  75.650  1.00 177.54 ? 1046 GLU A CA  1 
ATOM 7423 C C   . GLU A 1 1046 ? 80.175  83.852  76.109  1.00 174.43 ? 1046 GLU A C   1 
ATOM 7424 O O   . GLU A 1 1046 ? 80.220  84.861  75.411  1.00 168.67 ? 1046 GLU A O   1 
ATOM 7425 C CB  . GLU A 1 1046 ? 79.965  81.592  75.012  1.00 193.22 ? 1046 GLU A CB  1 
ATOM 7426 C CG  . GLU A 1 1046 ? 79.083  82.195  73.933  1.00 216.85 ? 1046 GLU A CG  1 
ATOM 7427 C CD  . GLU A 1 1046 ? 77.831  82.884  74.448  1.00 231.39 ? 1046 GLU A CD  1 
ATOM 7428 O OE1 . GLU A 1 1046 ? 77.664  84.096  74.195  1.00 236.57 ? 1046 GLU A OE1 1 
ATOM 7429 O OE2 . GLU A 1 1046 ? 77.022  82.200  75.100  1.00 241.53 ? 1046 GLU A OE2 1 
ATOM 7430 N N   . LYS A 1 1047 ? 79.452  83.779  77.237  1.00 177.21 ? 1047 LYS A N   1 
ATOM 7431 C CA  . LYS A 1 1047 ? 78.597  84.881  77.663  1.00 178.57 ? 1047 LYS A CA  1 
ATOM 7432 C C   . LYS A 1 1047 ? 78.825  85.217  79.136  1.00 151.16 ? 1047 LYS A C   1 
ATOM 7433 O O   . LYS A 1 1047 ? 77.988  84.931  79.991  1.00 143.61 ? 1047 LYS A O   1 
ATOM 7434 C CB  . LYS A 1 1047 ? 77.119  84.559  77.413  1.00 203.70 ? 1047 LYS A CB  1 
ATOM 7435 C CG  . LYS A 1 1047 ? 76.631  83.220  77.953  1.00 221.81 ? 1047 LYS A CG  1 
ATOM 7436 C CD  . LYS A 1 1047 ? 75.141  83.014  77.776  1.00 237.71 ? 1047 LYS A CD  1 
ATOM 7437 C CE  . LYS A 1 1047 ? 74.700  81.593  78.061  1.00 253.54 ? 1047 LYS A CE  1 
ATOM 7438 N NZ  . LYS A 1 1047 ? 75.310  80.626  77.117  1.00 260.62 ? 1047 LYS A NZ  1 
ATOM 7439 N N   . TYR A 1 1048 ? 79.955  85.870  79.415  1.00 134.08 ? 1048 TYR A N   1 
ATOM 7440 C CA  . TYR A 1 1048 ? 80.226  86.420  80.731  1.00 125.40 ? 1048 TYR A CA  1 
ATOM 7441 C C   . TYR A 1 1048 ? 80.242  87.939  80.639  1.00 122.35 ? 1048 TYR A C   1 
ATOM 7442 O O   . TYR A 1 1048 ? 81.014  88.500  79.863  1.00 126.92 ? 1048 TYR A O   1 
ATOM 7443 C CB  . TYR A 1 1048 ? 81.576  85.931  81.246  1.00 125.91 ? 1048 TYR A CB  1 
ATOM 7444 C CG  . TYR A 1 1048 ? 81.964  86.442  82.610  1.00 132.24 ? 1048 TYR A CG  1 
ATOM 7445 C CD1 . TYR A 1 1048 ? 81.238  86.097  83.737  1.00 147.97 ? 1048 TYR A CD1 1 
ATOM 7446 C CD2 . TYR A 1 1048 ? 83.084  87.241  82.781  1.00 134.25 ? 1048 TYR A CD2 1 
ATOM 7447 C CE1 . TYR A 1 1048 ? 81.604  86.545  84.997  1.00 161.36 ? 1048 TYR A CE1 1 
ATOM 7448 C CE2 . TYR A 1 1048 ? 83.455  87.710  84.029  1.00 144.29 ? 1048 TYR A CE2 1 
ATOM 7449 C CZ  . TYR A 1 1048 ? 82.718  87.354  85.146  1.00 159.90 ? 1048 TYR A CZ  1 
ATOM 7450 O OH  . TYR A 1 1048 ? 83.072  87.800  86.401  1.00 165.75 ? 1048 TYR A OH  1 
ATOM 7451 N N   . ASP A 1 1049 ? 79.395  88.587  81.444  1.00 119.74 ? 1049 ASP A N   1 
ATOM 7452 C CA  . ASP A 1 1049 ? 79.287  90.035  81.428  1.00 118.21 ? 1049 ASP A CA  1 
ATOM 7453 C C   . ASP A 1 1049 ? 79.988  90.578  82.664  1.00 101.21 ? 1049 ASP A C   1 
ATOM 7454 O O   . ASP A 1 1049 ? 79.547  90.333  83.780  1.00 97.09  ? 1049 ASP A O   1 
ATOM 7455 C CB  . ASP A 1 1049 ? 77.825  90.476  81.376  1.00 134.11 ? 1049 ASP A CB  1 
ATOM 7456 C CG  . ASP A 1 1049 ? 77.021  89.759  80.304  1.00 154.35 ? 1049 ASP A CG  1 
ATOM 7457 O OD1 . ASP A 1 1049 ? 76.953  88.508  80.361  1.00 165.13 ? 1049 ASP A OD1 1 
ATOM 7458 O OD2 . ASP A 1 1049 ? 76.476  90.451  79.418  1.00 161.53 ? 1049 ASP A OD2 1 
ATOM 7459 N N   . PRO A 1 1050 ? 81.095  91.335  82.519  1.00 105.61 ? 1050 PRO A N   1 
ATOM 7460 C CA  . PRO A 1 1050 ? 81.865  91.752  83.685  1.00 108.63 ? 1050 PRO A CA  1 
ATOM 7461 C C   . PRO A 1 1050 ? 81.006  92.534  84.674  1.00 111.30 ? 1050 PRO A C   1 
ATOM 7462 O O   . PRO A 1 1050 ? 81.077  92.287  85.870  1.00 119.57 ? 1050 PRO A O   1 
ATOM 7463 C CB  . PRO A 1 1050 ? 83.004  92.591  83.096  1.00 116.18 ? 1050 PRO A CB  1 
ATOM 7464 C CG  . PRO A 1 1050 ? 82.513  93.005  81.723  1.00 128.44 ? 1050 PRO A CG  1 
ATOM 7465 C CD  . PRO A 1 1050 ? 81.644  91.855  81.259  1.00 120.55 ? 1050 PRO A CD  1 
ATOM 7466 N N   . MET A 1 1051 ? 80.187  93.464  84.170  1.00 111.51 ? 1051 MET A N   1 
ATOM 7467 C CA  . MET A 1 1051 ? 79.218  94.161  85.003  1.00 111.39 ? 1051 MET A CA  1 
ATOM 7468 C C   . MET A 1 1051 ? 77.815  93.920  84.444  1.00 103.61 ? 1051 MET A C   1 
ATOM 7469 O O   . MET A 1 1051 ? 77.296  94.720  83.670  1.00 107.16 ? 1051 MET A O   1 
ATOM 7470 C CB  . MET A 1 1051 ? 79.506  95.668  85.070  1.00 117.99 ? 1051 MET A CB  1 
ATOM 7471 C CG  . MET A 1 1051 ? 80.067  96.136  86.411  1.00 122.62 ? 1051 MET A CG  1 
ATOM 7472 S SD  . MET A 1 1051 ? 81.797  96.729  86.426  1.00 130.37 ? 1051 MET A SD  1 
ATOM 7473 C CE  . MET A 1 1051 ? 82.565  95.722  85.159  1.00 133.03 ? 1051 MET A CE  1 
ATOM 7474 N N   . PRO A 1 1052 ? 77.135  92.822  84.836  1.00 97.07  ? 1052 PRO A N   1 
ATOM 7475 C CA  . PRO A 1 1052 ? 75.857  92.455  84.233  1.00 99.62  ? 1052 PRO A CA  1 
ATOM 7476 C C   . PRO A 1 1052 ? 74.637  93.154  84.830  1.00 108.01 ? 1052 PRO A C   1 
ATOM 7477 O O   . PRO A 1 1052 ? 74.748  93.872  85.819  1.00 107.85 ? 1052 PRO A O   1 
ATOM 7478 C CB  . PRO A 1 1052 ? 75.793  90.958  84.557  1.00 107.64 ? 1052 PRO A CB  1 
ATOM 7479 C CG  . PRO A 1 1052 ? 76.421  90.871  85.927  1.00 110.73 ? 1052 PRO A CG  1 
ATOM 7480 C CD  . PRO A 1 1052 ? 77.537  91.895  85.903  1.00 105.10 ? 1052 PRO A CD  1 
ATOM 7481 N N   . PRO A 1 1053 ? 73.438  92.952  84.236  1.00 134.32 ? 1053 PRO A N   1 
ATOM 7482 C CA  . PRO A 1 1053 ? 72.175  93.428  84.807  1.00 150.91 ? 1053 PRO A CA  1 
ATOM 7483 C C   . PRO A 1 1053 ? 71.860  92.793  86.159  1.00 163.74 ? 1053 PRO A C   1 
ATOM 7484 O O   . PRO A 1 1053 ? 72.134  91.612  86.358  1.00 176.14 ? 1053 PRO A O   1 
ATOM 7485 C CB  . PRO A 1 1053 ? 71.118  92.973  83.785  1.00 159.80 ? 1053 PRO A CB  1 
ATOM 7486 C CG  . PRO A 1 1053 ? 71.893  92.779  82.501  1.00 159.44 ? 1053 PRO A CG  1 
ATOM 7487 C CD  . PRO A 1 1053 ? 73.242  92.267  82.951  1.00 146.13 ? 1053 PRO A CD  1 
ATOM 7488 N N   . GLU A 1 1054 ? 71.237  93.572  87.054  1.00 173.39 ? 1054 GLU A N   1 
ATOM 7489 C CA  . GLU A 1 1054 ? 71.005  93.160  88.432  1.00 190.76 ? 1054 GLU A CA  1 
ATOM 7490 C C   . GLU A 1 1054 ? 70.102  91.925  88.477  1.00 191.50 ? 1054 GLU A C   1 
ATOM 7491 O O   . GLU A 1 1054 ? 70.359  91.002  89.247  1.00 194.93 ? 1054 GLU A O   1 
ATOM 7492 C CB  . GLU A 1 1054 ? 70.438  94.338  89.234  1.00 214.26 ? 1054 GLU A CB  1 
ATOM 7493 C CG  . GLU A 1 1054 ? 70.285  94.083  90.733  1.00 242.67 ? 1054 GLU A CG  1 
ATOM 7494 C CD  . GLU A 1 1054 ? 69.072  93.276  91.178  1.00 264.29 ? 1054 GLU A CD  1 
ATOM 7495 O OE1 . GLU A 1 1054 ? 68.305  92.813  90.297  1.00 273.12 ? 1054 GLU A OE1 1 
ATOM 7496 O OE2 . GLU A 1 1054 ? 68.898  93.103  92.412  1.00 272.81 ? 1054 GLU A OE2 1 
ATOM 7497 N N   . SER A 1 1055 ? 69.055  91.898  87.643  1.00 190.64 ? 1055 SER A N   1 
ATOM 7498 C CA  . SER A 1 1055 ? 68.065  90.834  87.687  1.00 196.01 ? 1055 SER A CA  1 
ATOM 7499 C C   . SER A 1 1055 ? 68.698  89.467  87.420  1.00 192.80 ? 1055 SER A C   1 
ATOM 7500 O O   . SER A 1 1055 ? 68.342  88.493  88.075  1.00 196.64 ? 1055 SER A O   1 
ATOM 7501 C CB  . SER A 1 1055 ? 66.951  91.110  86.718  1.00 202.10 ? 1055 SER A CB  1 
ATOM 7502 O OG  . SER A 1 1055 ? 67.444  91.182  85.389  1.00 201.70 ? 1055 SER A OG  1 
ATOM 7503 N N   . GLN A 1 1056 ? 69.646  89.410  86.474  1.00 195.23 ? 1056 GLN A N   1 
ATOM 7504 C CA  . GLN A 1 1056 ? 70.221  88.158  85.999  1.00 206.77 ? 1056 GLN A CA  1 
ATOM 7505 C C   . GLN A 1 1056 ? 71.128  87.485  87.036  1.00 209.17 ? 1056 GLN A C   1 
ATOM 7506 O O   . GLN A 1 1056 ? 71.159  86.257  87.089  1.00 216.97 ? 1056 GLN A O   1 
ATOM 7507 C CB  . GLN A 1 1056 ? 71.024  88.397  84.717  1.00 217.20 ? 1056 GLN A CB  1 
ATOM 7508 C CG  . GLN A 1 1056 ? 70.172  88.767  83.511  1.00 224.77 ? 1056 GLN A CG  1 
ATOM 7509 C CD  . GLN A 1 1056 ? 70.997  88.898  82.254  1.00 228.73 ? 1056 GLN A CD  1 
ATOM 7510 O OE1 . GLN A 1 1056 ? 71.913  89.712  82.175  1.00 212.57 ? 1056 GLN A OE1 1 
ATOM 7511 N NE2 . GLN A 1 1056 ? 70.679  88.090  81.256  1.00 237.27 ? 1056 GLN A NE2 1 
ATOM 7512 N N   . ARG A 1 1057 ? 71.850  88.274  87.854  1.00 192.95 ? 1057 ARG A N   1 
ATOM 7513 C CA  . ARG A 1 1057 ? 73.047  87.834  88.570  1.00 174.75 ? 1057 ARG A CA  1 
ATOM 7514 C C   . ARG A 1 1057 ? 72.809  86.658  89.520  1.00 175.51 ? 1057 ARG A C   1 
ATOM 7515 O O   . ARG A 1 1057 ? 73.634  85.747  89.571  1.00 181.76 ? 1057 ARG A O   1 
ATOM 7516 C CB  . ARG A 1 1057 ? 73.635  88.965  89.416  1.00 165.00 ? 1057 ARG A CB  1 
ATOM 7517 C CG  . ARG A 1 1057 ? 74.095  90.170  88.614  1.00 173.39 ? 1057 ARG A CG  1 
ATOM 7518 C CD  . ARG A 1 1057 ? 74.675  91.258  89.491  1.00 179.60 ? 1057 ARG A CD  1 
ATOM 7519 N NE  . ARG A 1 1057 ? 74.950  92.473  88.731  1.00 195.41 ? 1057 ARG A NE  1 
ATOM 7520 C CZ  . ARG A 1 1057 ? 74.407  93.668  88.954  1.00 206.87 ? 1057 ARG A CZ  1 
ATOM 7521 N NH1 . ARG A 1 1057 ? 73.594  93.870  89.977  1.00 202.14 ? 1057 ARG A NH1 1 
ATOM 7522 N NH2 . ARG A 1 1057 ? 74.726  94.685  88.172  1.00 216.15 ? 1057 ARG A NH2 1 
ATOM 7523 N N   . LYS A 1 1058 ? 71.756  86.723  90.346  1.00 178.09 ? 1058 LYS A N   1 
ATOM 7524 C CA  . LYS A 1 1058 ? 71.428  85.643  91.271  1.00 183.81 ? 1058 LYS A CA  1 
ATOM 7525 C C   . LYS A 1 1058 ? 72.325  85.751  92.509  1.00 176.26 ? 1058 LYS A C   1 
ATOM 7526 O O   . LYS A 1 1058 ? 73.150  86.655  92.595  1.00 171.08 ? 1058 LYS A O   1 
ATOM 7527 C CB  . LYS A 1 1058 ? 71.557  84.285  90.565  1.00 184.96 ? 1058 LYS A CB  1 
ATOM 7528 C CG  . LYS A 1 1058 ? 70.888  83.102  91.252  1.00 194.60 ? 1058 LYS A CG  1 
ATOM 7529 C CD  . LYS A 1 1058 ? 70.835  81.856  90.392  1.00 204.01 ? 1058 LYS A CD  1 
ATOM 7530 C CE  . LYS A 1 1058 ? 72.203  81.259  90.137  1.00 219.84 ? 1058 LYS A CE  1 
ATOM 7531 N NZ  . LYS A 1 1058 ? 72.115  80.012  89.340  1.00 230.05 ? 1058 LYS A NZ  1 
ATOM 7532 N N   . ILE A 1 1059 ? 72.105  84.860  93.490  1.00 156.64 ? 1059 ILE A N   1 
ATOM 7533 C CA  . ILE A 1 1059 ? 72.903  84.758  94.706  1.00 143.94 ? 1059 ILE A CA  1 
ATOM 7534 C C   . ILE A 1 1059 ? 73.573  83.383  94.731  1.00 137.46 ? 1059 ILE A C   1 
ATOM 7535 O O   . ILE A 1 1059 ? 72.907  82.380  94.472  1.00 138.58 ? 1059 ILE A O   1 
ATOM 7536 C CB  . ILE A 1 1059 ? 72.018  84.940  95.961  1.00 164.14 ? 1059 ILE A CB  1 
ATOM 7537 C CG1 . ILE A 1 1059 ? 71.251  86.266  95.972  1.00 178.77 ? 1059 ILE A CG1 1 
ATOM 7538 C CG2 . ILE A 1 1059 ? 72.840  84.782  97.234  1.00 169.20 ? 1059 ILE A CG2 1 
ATOM 7539 C CD1 . ILE A 1 1059 ? 70.171  86.399  94.923  1.00 184.90 ? 1059 ILE A CD1 1 
ATOM 7540 N N   . LEU A 1 1060 ? 74.869  83.335  95.084  1.00 130.64 ? 1060 LEU A N   1 
ATOM 7541 C CA  . LEU A 1 1060 ? 75.606  82.079  95.176  1.00 122.80 ? 1060 LEU A CA  1 
ATOM 7542 C C   . LEU A 1 1060 ? 76.037  81.759  96.610  1.00 110.08 ? 1060 LEU A C   1 
ATOM 7543 O O   . LEU A 1 1060 ? 76.009  80.597  96.998  1.00 107.92 ? 1060 LEU A O   1 
ATOM 7544 C CB  . LEU A 1 1060 ? 76.822  82.137  94.245  1.00 128.00 ? 1060 LEU A CB  1 
ATOM 7545 C CG  . LEU A 1 1060 ? 76.507  82.268  92.753  1.00 144.90 ? 1060 LEU A CG  1 
ATOM 7546 C CD1 . LEU A 1 1060 ? 77.731  81.939  91.910  1.00 153.31 ? 1060 LEU A CD1 1 
ATOM 7547 C CD2 . LEU A 1 1060 ? 75.330  81.388  92.345  1.00 152.13 ? 1060 LEU A CD2 1 
ATOM 7548 N N   . MET A 1 1061 ? 76.460  82.769  97.383  1.00 105.69 ? 1061 MET A N   1 
ATOM 7549 C CA  . MET A 1 1061 ? 77.001  82.554  98.719  1.00 102.09 ? 1061 MET A CA  1 
ATOM 7550 C C   . MET A 1 1061 ? 76.303  83.462  99.732  1.00 103.57 ? 1061 MET A C   1 
ATOM 7551 O O   . MET A 1 1061 ? 75.779  84.511  99.362  1.00 122.73 ? 1061 MET A O   1 
ATOM 7552 C CB  . MET A 1 1061 ? 78.501  82.857  98.748  1.00 110.69 ? 1061 MET A CB  1 
ATOM 7553 C CG  . MET A 1 1061 ? 79.365  81.638  98.987  1.00 132.80 ? 1061 MET A CG  1 
ATOM 7554 S SD  . MET A 1 1061 ? 81.006  82.092  99.600  1.00 165.64 ? 1061 MET A SD  1 
ATOM 7555 C CE  . MET A 1 1061 ? 81.985  80.722  98.987  1.00 173.01 ? 1061 MET A CE  1 
ATOM 7556 N N   . THR A 1 1062 ? 76.332  83.062  101.014 1.00 86.66  ? 1062 THR A N   1 
ATOM 7557 C CA  . THR A 1 1062 ? 75.717  83.832  102.089 1.00 76.66  ? 1062 THR A CA  1 
ATOM 7558 C C   . THR A 1 1062 ? 76.587  83.804  103.345 1.00 62.63  ? 1062 THR A C   1 
ATOM 7559 O O   . THR A 1 1062 ? 76.197  83.226  104.356 1.00 63.37  ? 1062 THR A O   1 
ATOM 7560 C CB  . THR A 1 1062 ? 74.314  83.311  102.427 1.00 84.27  ? 1062 THR A CB  1 
ATOM 7561 O OG1 . THR A 1 1062 ? 74.424  81.927  102.769 1.00 90.40  ? 1062 THR A OG1 1 
ATOM 7562 C CG2 . THR A 1 1062 ? 73.325  83.483  101.295 1.00 89.11  ? 1062 THR A CG2 1 
ATOM 7563 N N   . LEU A 1 1063 ? 77.754  84.452  103.287 1.00 53.65  ? 1063 LEU A N   1 
ATOM 7564 C CA  . LEU A 1 1063 ? 78.619  84.566  104.449 1.00 52.06  ? 1063 LEU A CA  1 
ATOM 7565 C C   . LEU A 1 1063 ? 77.870  85.299  105.560 1.00 59.20  ? 1063 LEU A C   1 
ATOM 7566 O O   . LEU A 1 1063 ? 77.105  86.208  105.267 1.00 70.66  ? 1063 LEU A O   1 
ATOM 7567 C CB  . LEU A 1 1063 ? 79.894  85.307  104.038 1.00 52.94  ? 1063 LEU A CB  1 
ATOM 7568 C CG  . LEU A 1 1063 ? 80.889  85.624  105.156 1.00 59.28  ? 1063 LEU A CG  1 
ATOM 7569 C CD1 . LEU A 1 1063 ? 81.339  84.361  105.895 1.00 72.06  ? 1063 LEU A CD1 1 
ATOM 7570 C CD2 . LEU A 1 1063 ? 82.101  86.360  104.601 1.00 54.03  ? 1063 LEU A CD2 1 
ATOM 7571 N N   . THR A 1 1064 ? 78.074  84.883  106.825 1.00 63.10  ? 1064 THR A N   1 
ATOM 7572 C CA  . THR A 1 1064 ? 77.381  85.455  107.979 1.00 62.00  ? 1064 THR A CA  1 
ATOM 7573 C C   . THR A 1 1064 ? 78.355  85.761  109.114 1.00 49.55  ? 1064 THR A C   1 
ATOM 7574 O O   . THR A 1 1064 ? 78.293  85.138  110.166 1.00 48.27  ? 1064 THR A O   1 
ATOM 7575 C CB  . THR A 1 1064 ? 76.321  84.506  108.562 1.00 69.10  ? 1064 THR A CB  1 
ATOM 7576 O OG1 . THR A 1 1064 ? 76.989  83.278  108.850 1.00 73.28  ? 1064 THR A OG1 1 
ATOM 7577 C CG2 . THR A 1 1064 ? 75.145  84.251  107.646 1.00 73.50  ? 1064 THR A CG2 1 
ATOM 7578 N N   . VAL A 1 1065 ? 79.211  86.761  108.923 1.00 46.16  ? 1065 VAL A N   1 
ATOM 7579 C CA  . VAL A 1 1065 ? 80.145  87.153  109.962 1.00 49.80  ? 1065 VAL A CA  1 
ATOM 7580 C C   . VAL A 1 1065 ? 79.362  87.651  111.173 1.00 56.68  ? 1065 VAL A C   1 
ATOM 7581 O O   . VAL A 1 1065 ? 78.346  88.316  111.017 1.00 65.36  ? 1065 VAL A O   1 
ATOM 7582 C CB  . VAL A 1 1065 ? 81.120  88.240  109.472 1.00 54.37  ? 1065 VAL A CB  1 
ATOM 7583 C CG1 . VAL A 1 1065 ? 82.128  88.615  110.552 1.00 52.93  ? 1065 VAL A CG1 1 
ATOM 7584 C CG2 . VAL A 1 1065 ? 81.836  87.820  108.192 1.00 60.68  ? 1065 VAL A CG2 1 
ATOM 7585 N N   . LYS A 1 1066 ? 79.858  87.325  112.375 1.00 63.69  ? 1066 LYS A N   1 
ATOM 7586 C CA  . LYS A 1 1066 ? 79.455  87.930  113.641 1.00 59.98  ? 1066 LYS A CA  1 
ATOM 7587 C C   . LYS A 1 1066 ? 80.732  88.212  114.425 1.00 44.30  ? 1066 LYS A C   1 
ATOM 7588 O O   . LYS A 1 1066 ? 81.518  87.302  114.621 1.00 47.68  ? 1066 LYS A O   1 
ATOM 7589 C CB  . LYS A 1 1066 ? 78.552  86.951  114.398 1.00 69.21  ? 1066 LYS A CB  1 
ATOM 7590 C CG  . LYS A 1 1066 ? 78.216  87.309  115.841 1.00 84.90  ? 1066 LYS A CG  1 
ATOM 7591 C CD  . LYS A 1 1066 ? 77.794  86.096  116.652 1.00 101.41 ? 1066 LYS A CD  1 
ATOM 7592 C CE  . LYS A 1 1066 ? 77.030  86.442  117.915 1.00 113.79 ? 1066 LYS A CE  1 
ATOM 7593 N NZ  . LYS A 1 1066 ? 76.630  85.230  118.672 1.00 112.21 ? 1066 LYS A NZ  1 
ATOM 7594 N N   . VAL A 1 1067 ? 80.985  89.453  114.817 1.00 36.55  ? 1067 VAL A N   1 
ATOM 7595 C CA  . VAL A 1 1067 ? 82.270  89.756  115.415 1.00 39.70  ? 1067 VAL A CA  1 
ATOM 7596 C C   . VAL A 1 1067 ? 82.156  89.583  116.925 1.00 46.87  ? 1067 VAL A C   1 
ATOM 7597 O O   . VAL A 1 1067 ? 81.393  90.300  117.574 1.00 61.25  ? 1067 VAL A O   1 
ATOM 7598 C CB  . VAL A 1 1067 ? 82.752  91.170  115.051 1.00 46.23  ? 1067 VAL A CB  1 
ATOM 7599 C CG1 . VAL A 1 1067 ? 84.198  91.425  115.480 1.00 45.14  ? 1067 VAL A CG1 1 
ATOM 7600 C CG2 . VAL A 1 1067 ? 82.579  91.428  113.563 1.00 54.75  ? 1067 VAL A CG2 1 
ATOM 7601 N N   . LEU A 1 1068 ? 82.940  88.640  117.477 1.00 43.61  ? 1068 LEU A N   1 
ATOM 7602 C CA  . LEU A 1 1068 ? 82.805  88.204  118.860 1.00 38.65  ? 1068 LEU A CA  1 
ATOM 7603 C C   . LEU A 1 1068 ? 83.924  88.730  119.745 1.00 33.43  ? 1068 LEU A C   1 
ATOM 7604 O O   . LEU A 1 1068 ? 83.834  88.571  120.964 1.00 42.17  ? 1068 LEU A O   1 
ATOM 7605 C CB  . LEU A 1 1068 ? 82.801  86.674  118.919 1.00 39.44  ? 1068 LEU A CB  1 
ATOM 7606 C CG  . LEU A 1 1068 ? 81.514  86.011  118.441 1.00 51.99  ? 1068 LEU A CG  1 
ATOM 7607 C CD1 . LEU A 1 1068 ? 81.557  84.533  118.738 1.00 59.29  ? 1068 LEU A CD1 1 
ATOM 7608 C CD2 . LEU A 1 1068 ? 80.281  86.641  119.082 1.00 60.72  ? 1068 LEU A CD2 1 
ATOM 7609 N N   . GLY A 1 1069 ? 84.988  89.295  119.175 1.00 26.74  ? 1069 GLY A N   1 
ATOM 7610 C CA  . GLY A 1 1069 ? 86.182  89.437  119.991 1.00 25.07  ? 1069 GLY A CA  1 
ATOM 7611 C C   . GLY A 1 1069 ? 87.263  90.327  119.400 1.00 22.14  ? 1069 GLY A C   1 
ATOM 7612 O O   . GLY A 1 1069 ? 87.142  90.816  118.289 1.00 27.17  ? 1069 GLY A O   1 
ATOM 7613 N N   . ALA A 1 1070 ? 88.318  90.512  120.184 1.00 19.09  ? 1070 ALA A N   1 
ATOM 7614 C CA  . ALA A 1 1070 ? 89.505  91.233  119.774 1.00 18.92  ? 1070 ALA A CA  1 
ATOM 7615 C C   . ALA A 1 1070 ? 90.632  90.883  120.740 1.00 21.65  ? 1070 ALA A C   1 
ATOM 7616 O O   . ALA A 1 1070 ? 90.386  90.202  121.733 1.00 28.50  ? 1070 ALA A O   1 
ATOM 7617 C CB  . ALA A 1 1070 ? 89.204  92.697  119.764 1.00 19.70  ? 1070 ALA A CB  1 
ATOM 7618 N N   . ARG A 1 1071 ? 91.843  91.369  120.468 1.00 22.71  ? 1071 ARG A N   1 
ATOM 7619 C CA  . ARG A 1 1071 ? 92.960  91.142  121.421 1.00 28.24  ? 1071 ARG A CA  1 
ATOM 7620 C C   . ARG A 1 1071 ? 94.202  91.909  120.971 1.00 30.15  ? 1071 ARG A C   1 
ATOM 7621 O O   . ARG A 1 1071 ? 94.591  91.745  119.811 1.00 37.03  ? 1071 ARG A O   1 
ATOM 7622 C CB  . ARG A 1 1071 ? 93.258  89.650  121.558 1.00 43.65  ? 1071 ARG A CB  1 
ATOM 7623 C CG  . ARG A 1 1071 ? 94.266  89.315  122.647 1.00 58.63  ? 1071 ARG A CG  1 
ATOM 7624 C CD  . ARG A 1 1071 ? 94.423  87.818  122.819 1.00 74.58  ? 1071 ARG A CD  1 
ATOM 7625 N NE  . ARG A 1 1071 ? 93.240  87.196  123.394 1.00 69.74  ? 1071 ARG A NE  1 
ATOM 7626 C CZ  . ARG A 1 1071 ? 93.236  86.527  124.539 1.00 62.72  ? 1071 ARG A CZ  1 
ATOM 7627 N NH1 . ARG A 1 1071 ? 94.302  86.551  125.318 1.00 58.14  ? 1071 ARG A NH1 1 
ATOM 7628 N NH2 . ARG A 1 1071 ? 92.171  85.833  124.901 1.00 64.31  ? 1071 ARG A NH2 1 
ATOM 7629 N N   . HIS A 1 1072 ? 94.769  92.734  121.848 1.00 34.36  ? 1072 HIS A N   1 
ATOM 7630 C CA  . HIS A 1 1072 ? 96.011  93.509  121.557 1.00 46.18  ? 1072 HIS A CA  1 
ATOM 7631 C C   . HIS A 1 1072 ? 95.856  94.501  120.397 1.00 48.65  ? 1072 HIS A C   1 
ATOM 7632 O O   . HIS A 1 1072 ? 96.901  94.874  119.831 1.00 55.61  ? 1072 HIS A O   1 
ATOM 7633 C CB  . HIS A 1 1072 ? 97.195  92.581  121.286 1.00 52.72  ? 1072 HIS A CB  1 
ATOM 7634 C CG  . HIS A 1 1072 ? 97.735  91.890  122.485 1.00 60.11  ? 1072 HIS A CG  1 
ATOM 7635 N ND1 . HIS A 1 1072 ? 96.971  91.063  123.277 1.00 63.51  ? 1072 HIS A ND1 1 
ATOM 7636 C CD2 . HIS A 1 1072 ? 98.958  91.897  123.022 1.00 58.63  ? 1072 HIS A CD2 1 
ATOM 7637 C CE1 . HIS A 1 1072 ? 97.721  90.595  124.260 1.00 73.08  ? 1072 HIS A CE1 1 
ATOM 7638 N NE2 . HIS A 1 1072 ? 98.931  91.084  124.121 1.00 61.87  ? 1072 HIS A NE2 1 
ATOM 7639 N N   . LEU A 1 1073 ? 94.641  94.948  120.072 1.00 39.87  ? 1073 LEU A N   1 
ATOM 7640 C CA  . LEU A 1 1073 ? 94.512  95.995  119.025 1.00 30.99  ? 1073 LEU A CA  1 
ATOM 7641 C C   . LEU A 1 1073 ? 95.577  97.049  119.327 1.00 29.91  ? 1073 LEU A C   1 
ATOM 7642 O O   . LEU A 1 1073 ? 95.708  97.424  120.501 1.00 32.36  ? 1073 LEU A O   1 
ATOM 7643 C CB  . LEU A 1 1073 ? 93.093  96.564  119.056 1.00 30.53  ? 1073 LEU A CB  1 
ATOM 7644 C CG  . LEU A 1 1073 ? 91.982  95.522  118.943 1.00 38.13  ? 1073 LEU A CG  1 
ATOM 7645 C CD1 . LEU A 1 1073 ? 90.637  96.186  118.713 1.00 38.86  ? 1073 LEU A CD1 1 
ATOM 7646 C CD2 . LEU A 1 1073 ? 92.279  94.531  117.830 1.00 42.37  ? 1073 LEU A CD2 1 
ATOM 7647 N N   . PRO A 1 1074 ? 96.328  97.566  118.335 1.00 38.42  ? 1074 PRO A N   1 
ATOM 7648 C CA  . PRO A 1 1074 ? 97.448  98.461  118.610 1.00 45.18  ? 1074 PRO A CA  1 
ATOM 7649 C C   . PRO A 1 1074 ? 96.946  99.823  119.066 1.00 58.15  ? 1074 PRO A C   1 
ATOM 7650 O O   . PRO A 1 1074 ? 95.834  100.220 118.718 1.00 67.44  ? 1074 PRO A O   1 
ATOM 7651 C CB  . PRO A 1 1074 ? 98.128  98.622  117.252 1.00 51.49  ? 1074 PRO A CB  1 
ATOM 7652 C CG  . PRO A 1 1074 ? 96.970  98.442  116.271 1.00 56.22  ? 1074 PRO A CG  1 
ATOM 7653 C CD  . PRO A 1 1074 ? 96.081  97.377  116.898 1.00 49.68  ? 1074 PRO A CD  1 
ATOM 7654 N N   . LYS A 1 1075 ? 97.767  100.525 119.850 1.00 67.05  ? 1075 LYS A N   1 
ATOM 7655 C CA  . LYS A 1 1075 ? 97.432  101.868 120.288 1.00 74.54  ? 1075 LYS A CA  1 
ATOM 7656 C C   . LYS A 1 1075 ? 98.064  102.857 119.315 1.00 81.40  ? 1075 LYS A C   1 
ATOM 7657 O O   . LYS A 1 1075 ? 99.216  102.670 118.930 1.00 82.13  ? 1075 LYS A O   1 
ATOM 7658 C CB  . LYS A 1 1075 ? 97.924  102.089 121.721 1.00 84.86  ? 1075 LYS A CB  1 
ATOM 7659 C CG  . LYS A 1 1075 ? 97.612  103.462 122.298 1.00 100.50 ? 1075 LYS A CG  1 
ATOM 7660 C CD  . LYS A 1 1075 ? 98.022  103.656 123.745 1.00 110.52 ? 1075 LYS A CD  1 
ATOM 7661 C CE  . LYS A 1 1075 ? 99.521  103.762 123.945 1.00 124.56 ? 1075 LYS A CE  1 
ATOM 7662 N NZ  . LYS A 1 1075 ? 100.234 102.484 123.685 1.00 132.31 ? 1075 LYS A NZ  1 
ATOM 7663 N N   . LEU A 1 1076 ? 97.307  103.900 118.934 1.00 91.53  ? 1076 LEU A N   1 
ATOM 7664 C CA  . LEU A 1 1076 ? 97.725  104.832 117.896 1.00 94.53  ? 1076 LEU A CA  1 
ATOM 7665 C C   . LEU A 1 1076 ? 98.480  106.018 118.487 1.00 87.00  ? 1076 LEU A C   1 
ATOM 7666 O O   . LEU A 1 1076 ? 99.573  106.351 118.030 1.00 90.42  ? 1076 LEU A O   1 
ATOM 7667 C CB  . LEU A 1 1076 ? 96.498  105.324 117.119 1.00 100.54 ? 1076 LEU A CB  1 
ATOM 7668 C CG  . LEU A 1 1076 ? 96.131  104.526 115.868 1.00 118.31 ? 1076 LEU A CG  1 
ATOM 7669 C CD1 . LEU A 1 1076 ? 95.284  105.369 114.921 1.00 120.48 ? 1076 LEU A CD1 1 
ATOM 7670 C CD2 . LEU A 1 1076 ? 97.364  103.995 115.142 1.00 131.74 ? 1076 LEU A CD2 1 
ATOM 7671 N N   . GLY A 1 1077 ? 97.857  106.684 119.460 1.00 84.64  ? 1077 GLY A N   1 
ATOM 7672 C CA  . GLY A 1 1077 ? 98.330  107.981 119.918 1.00 88.53  ? 1077 GLY A CA  1 
ATOM 7673 C C   . GLY A 1 1077 ? 98.699  107.968 121.397 1.00 85.83  ? 1077 GLY A C   1 
ATOM 7674 O O   . GLY A 1 1077 ? 99.609  107.247 121.803 1.00 90.88  ? 1077 GLY A O   1 
ATOM 7675 N N   . ARG A 1 1078 ? 98.002  108.801 122.177 1.00 72.56  ? 1078 ARG A N   1 
ATOM 7676 C CA  . ARG A 1 1078 ? 98.135  108.794 123.619 1.00 64.22  ? 1078 ARG A CA  1 
ATOM 7677 C C   . ARG A 1 1078 ? 96.734  108.709 124.187 1.00 58.42  ? 1078 ARG A C   1 
ATOM 7678 O O   . ARG A 1 1078 ? 96.244  109.673 124.756 1.00 64.56  ? 1078 ARG A O   1 
ATOM 7679 C CB  . ARG A 1 1078 ? 98.867  110.052 124.090 1.00 66.54  ? 1078 ARG A CB  1 
ATOM 7680 C CG  . ARG A 1 1078 ? 99.480  109.955 125.478 1.00 73.71  ? 1078 ARG A CG  1 
ATOM 7681 C CD  . ARG A 1 1078 ? 100.676 110.882 125.578 1.00 80.87  ? 1078 ARG A CD  1 
ATOM 7682 N NE  . ARG A 1 1078 ? 101.316 110.864 126.883 1.00 88.97  ? 1078 ARG A NE  1 
ATOM 7683 C CZ  . ARG A 1 1078 ? 102.462 111.477 127.158 1.00 100.56 ? 1078 ARG A CZ  1 
ATOM 7684 N NH1 . ARG A 1 1078 ? 103.134 112.090 126.198 1.00 101.40 ? 1078 ARG A NH1 1 
ATOM 7685 N NH2 . ARG A 1 1078 ? 102.937 111.470 128.393 1.00 109.41 ? 1078 ARG A NH2 1 
ATOM 7686 N N   . SER A 1 1079 ? 96.091  107.562 123.977 1.00 60.90  ? 1079 SER A N   1 
ATOM 7687 C CA  . SER A 1 1079 ? 94.716  107.368 124.401 1.00 66.62  ? 1079 SER A CA  1 
ATOM 7688 C C   . SER A 1 1079 ? 94.359  105.887 124.331 1.00 67.60  ? 1079 SER A C   1 
ATOM 7689 O O   . SER A 1 1079 ? 94.643  105.247 123.326 1.00 76.97  ? 1079 SER A O   1 
ATOM 7690 C CB  . SER A 1 1079 ? 93.781  108.164 123.529 1.00 72.49  ? 1079 SER A CB  1 
ATOM 7691 O OG  . SER A 1 1079 ? 94.064  109.556 123.590 1.00 79.38  ? 1079 SER A OG  1 
ATOM 7692 N N   . ILE A 1 1080 ? 93.726  105.337 125.369 1.00 61.84  ? 1080 ILE A N   1 
ATOM 7693 C CA  . ILE A 1 1080 ? 93.139  104.019 125.220 1.00 61.85  ? 1080 ILE A CA  1 
ATOM 7694 C C   . ILE A 1 1080 ? 92.115  104.168 124.108 1.00 52.80  ? 1080 ILE A C   1 
ATOM 7695 O O   . ILE A 1 1080 ? 91.411  105.169 124.065 1.00 59.49  ? 1080 ILE A O   1 
ATOM 7696 C CB  . ILE A 1 1080 ? 92.502  103.472 126.513 1.00 78.00  ? 1080 ILE A CB  1 
ATOM 7697 C CG1 . ILE A 1 1080 ? 93.493  103.484 127.684 1.00 98.02  ? 1080 ILE A CG1 1 
ATOM 7698 C CG2 . ILE A 1 1080 ? 91.949  102.072 126.266 1.00 75.41  ? 1080 ILE A CG2 1 
ATOM 7699 C CD1 . ILE A 1 1080 ? 93.767  104.858 128.277 1.00 110.03 ? 1080 ILE A CD1 1 
ATOM 7700 N N   . ALA A 1 1081 ? 92.083  103.218 123.179 1.00 48.69  ? 1081 ALA A N   1 
ATOM 7701 C CA  . ALA A 1 1081 ? 91.338  103.427 121.950 1.00 55.58  ? 1081 ALA A CA  1 
ATOM 7702 C C   . ALA A 1 1081 ? 90.091  102.557 121.919 1.00 56.70  ? 1081 ALA A C   1 
ATOM 7703 O O   . ALA A 1 1081 ? 90.188  101.356 121.676 1.00 59.10  ? 1081 ALA A O   1 
ATOM 7704 C CB  . ALA A 1 1081 ? 92.227  103.128 120.764 1.00 64.39  ? 1081 ALA A CB  1 
ATOM 7705 N N   . CYS A 1 1082 ? 88.921  103.180 122.082 1.00 61.02  ? 1082 CYS A N   1 
ATOM 7706 C CA  . CYS A 1 1082 ? 87.675  102.481 121.815 1.00 71.04  ? 1082 CYS A CA  1 
ATOM 7707 C C   . CYS A 1 1082 ? 87.763  101.851 120.432 1.00 59.66  ? 1082 CYS A C   1 
ATOM 7708 O O   . CYS A 1 1082 ? 88.280  102.480 119.527 1.00 71.38  ? 1082 CYS A O   1 
ATOM 7709 C CB  . CYS A 1 1082 ? 86.476  103.417 121.855 1.00 89.47  ? 1082 CYS A CB  1 
ATOM 7710 S SG  . CYS A 1 1082 ? 86.297  104.277 123.440 1.00 123.31 ? 1082 CYS A SG  1 
ATOM 7711 N N   . PRO A 1 1083 ? 87.345  100.590 120.231 1.00 49.58  ? 1083 PRO A N   1 
ATOM 7712 C CA  . PRO A 1 1083 ? 87.377  99.963  118.923 1.00 48.43  ? 1083 PRO A CA  1 
ATOM 7713 C C   . PRO A 1 1083 ? 86.018  99.567  118.366 1.00 47.65  ? 1083 PRO A C   1 
ATOM 7714 O O   . PRO A 1 1083 ? 85.242  98.905  119.046 1.00 49.67  ? 1083 PRO A O   1 
ATOM 7715 C CB  . PRO A 1 1083 ? 88.135  98.694  119.312 1.00 55.18  ? 1083 PRO A CB  1 
ATOM 7716 C CG  . PRO A 1 1083 ? 87.638  98.350  120.725 1.00 60.91  ? 1083 PRO A CG  1 
ATOM 7717 C CD  . PRO A 1 1083 ? 86.987  99.612  121.254 1.00 55.41  ? 1083 PRO A CD  1 
ATOM 7718 N N   . PHE A 1 1084 ? 85.745  99.936  117.111 1.00 52.51  ? 1084 PHE A N   1 
ATOM 7719 C CA  . PHE A 1 1084 ? 84.573  99.414  116.425 1.00 64.39  ? 1084 PHE A CA  1 
ATOM 7720 C C   . PHE A 1 1084 ? 85.037  98.686  115.166 1.00 63.90  ? 1084 PHE A C   1 
ATOM 7721 O O   . PHE A 1 1084 ? 85.882  99.197  114.443 1.00 77.55  ? 1084 PHE A O   1 
ATOM 7722 C CB  . PHE A 1 1084 ? 83.534  100.524 116.201 1.00 75.65  ? 1084 PHE A CB  1 
ATOM 7723 C CG  . PHE A 1 1084 ? 83.914  101.699 115.333 1.00 75.49  ? 1084 PHE A CG  1 
ATOM 7724 C CD1 . PHE A 1 1084 ? 84.110  101.534 113.976 1.00 77.34  ? 1084 PHE A CD1 1 
ATOM 7725 C CD2 . PHE A 1 1084 ? 83.978  102.983 115.853 1.00 86.72  ? 1084 PHE A CD2 1 
ATOM 7726 C CE1 . PHE A 1 1084 ? 84.406  102.609 113.161 1.00 86.97  ? 1084 PHE A CE1 1 
ATOM 7727 C CE2 . PHE A 1 1084 ? 84.289  104.059 115.039 1.00 99.13  ? 1084 PHE A CE2 1 
ATOM 7728 C CZ  . PHE A 1 1084 ? 84.504  103.867 113.696 1.00 97.17  ? 1084 PHE A CZ  1 
ATOM 7729 N N   . VAL A 1 1085 ? 84.518  97.479  114.925 1.00 52.81  ? 1085 VAL A N   1 
ATOM 7730 C CA  . VAL A 1 1085 ? 84.926  96.700  113.771 1.00 53.60  ? 1085 VAL A CA  1 
ATOM 7731 C C   . VAL A 1 1085 ? 83.868  96.847  112.679 1.00 58.88  ? 1085 VAL A C   1 
ATOM 7732 O O   . VAL A 1 1085 ? 82.686  96.719  112.969 1.00 64.41  ? 1085 VAL A O   1 
ATOM 7733 C CB  . VAL A 1 1085 ? 85.102  95.221  114.159 1.00 66.94  ? 1085 VAL A CB  1 
ATOM 7734 C CG1 . VAL A 1 1085 ? 85.408  94.342  112.946 1.00 73.26  ? 1085 VAL A CG1 1 
ATOM 7735 C CG2 . VAL A 1 1085 ? 86.146  95.057  115.258 1.00 71.97  ? 1085 VAL A CG2 1 
ATOM 7736 N N   . GLU A 1 1086 ? 84.285  97.092  111.425 1.00 56.40  ? 1086 GLU A N   1 
ATOM 7737 C CA  . GLU A 1 1086 ? 83.365  97.084  110.292 1.00 50.98  ? 1086 GLU A CA  1 
ATOM 7738 C C   . GLU A 1 1086 ? 83.685  95.935  109.353 1.00 41.98  ? 1086 GLU A C   1 
ATOM 7739 O O   . GLU A 1 1086 ? 84.717  95.955  108.696 1.00 43.62  ? 1086 GLU A O   1 
ATOM 7740 C CB  . GLU A 1 1086 ? 83.506  98.309  109.402 1.00 63.68  ? 1086 GLU A CB  1 
ATOM 7741 C CG  . GLU A 1 1086 ? 83.796  99.595  110.138 1.00 89.87  ? 1086 GLU A CG  1 
ATOM 7742 C CD  . GLU A 1 1086 ? 84.088  100.755 109.197 1.00 114.38 ? 1086 GLU A CD  1 
ATOM 7743 O OE1 . GLU A 1 1086 ? 84.466  100.491 108.031 1.00 120.84 ? 1086 GLU A OE1 1 
ATOM 7744 O OE2 . GLU A 1 1086 ? 83.904  101.922 109.618 1.00 125.25 ? 1086 GLU A OE2 1 
ATOM 7745 N N   . VAL A 1 1087 ? 82.795  94.951  109.277 1.00 36.86  ? 1087 VAL A N   1 
ATOM 7746 C CA  . VAL A 1 1087 ? 82.869  93.944  108.235 1.00 37.30  ? 1087 VAL A CA  1 
ATOM 7747 C C   . VAL A 1 1087 ? 82.507  94.639  106.928 1.00 47.75  ? 1087 VAL A C   1 
ATOM 7748 O O   . VAL A 1 1087 ? 81.747  95.593  106.947 1.00 57.78  ? 1087 VAL A O   1 
ATOM 7749 C CB  . VAL A 1 1087 ? 81.934  92.761  108.532 1.00 38.76  ? 1087 VAL A CB  1 
ATOM 7750 C CG1 . VAL A 1 1087 ? 82.294  91.527  107.714 1.00 41.49  ? 1087 VAL A CG1 1 
ATOM 7751 C CG2 . VAL A 1 1087 ? 81.923  92.418  110.012 1.00 42.73  ? 1087 VAL A CG2 1 
ATOM 7752 N N   . GLU A 1 1088 ? 83.112  94.215  105.811 1.00 57.37  ? 1088 GLU A N   1 
ATOM 7753 C CA  . GLU A 1 1088 ? 82.784  94.705  104.477 1.00 61.59  ? 1088 GLU A CA  1 
ATOM 7754 C C   . GLU A 1 1088 ? 82.886  93.540  103.499 1.00 62.65  ? 1088 GLU A C   1 
ATOM 7755 O O   . GLU A 1 1088 ? 83.583  92.571  103.785 1.00 77.12  ? 1088 GLU A O   1 
ATOM 7756 C CB  . GLU A 1 1088 ? 83.752  95.798  104.019 1.00 73.07  ? 1088 GLU A CB  1 
ATOM 7757 C CG  . GLU A 1 1088 ? 83.658  97.090  104.813 1.00 101.08 ? 1088 GLU A CG  1 
ATOM 7758 C CD  . GLU A 1 1088 ? 84.526  98.235  104.311 1.00 130.08 ? 1088 GLU A CD  1 
ATOM 7759 O OE1 . GLU A 1 1088 ? 85.103  98.101  103.214 1.00 139.74 ? 1088 GLU A OE1 1 
ATOM 7760 O OE2 . GLU A 1 1088 ? 84.611  99.271  105.011 1.00 131.37 ? 1088 GLU A OE2 1 
ATOM 7761 N N   . ILE A 1 1089 ? 82.198  93.638  102.357 1.00 53.84  ? 1089 ILE A N   1 
ATOM 7762 C CA  . ILE A 1 1089 ? 82.485  92.777  101.221 1.00 47.03  ? 1089 ILE A CA  1 
ATOM 7763 C C   . ILE A 1 1089 ? 82.902  93.662  100.059 1.00 52.07  ? 1089 ILE A C   1 
ATOM 7764 O O   . ILE A 1 1089 ? 82.134  93.848  99.120  1.00 53.54  ? 1089 ILE A O   1 
ATOM 7765 C CB  . ILE A 1 1089 ? 81.282  91.898  100.854 1.00 46.38  ? 1089 ILE A CB  1 
ATOM 7766 C CG1 . ILE A 1 1089 ? 80.886  90.975  102.005 1.00 54.36  ? 1089 ILE A CG1 1 
ATOM 7767 C CG2 . ILE A 1 1089 ? 81.560  91.108  99.585  1.00 46.68  ? 1089 ILE A CG2 1 
ATOM 7768 C CD1 . ILE A 1 1089 ? 81.604  89.630  102.019 1.00 58.20  ? 1089 ILE A CD1 1 
ATOM 7769 N N   . CYS A 1 1090 ? 84.106  94.240  100.162 1.00 62.38  ? 1090 CYS A N   1 
ATOM 7770 C CA  . CYS A 1 1090 ? 84.715  94.906  99.023  1.00 68.84  ? 1090 CYS A CA  1 
ATOM 7771 C C   . CYS A 1 1090 ? 84.471  94.044  97.795  1.00 77.99  ? 1090 CYS A C   1 
ATOM 7772 O O   . CYS A 1 1090 ? 84.748  92.851  97.822  1.00 86.69  ? 1090 CYS A O   1 
ATOM 7773 C CB  . CYS A 1 1090 ? 86.207  95.133  99.211  1.00 68.03  ? 1090 CYS A CB  1 
ATOM 7774 S SG  . CYS A 1 1090 ? 86.605  96.844  99.648  1.00 86.86  ? 1090 CYS A SG  1 
ATOM 7775 N N   . GLY A 1 1091 ? 83.904  94.645  96.749  1.00 87.71  ? 1091 GLY A N   1 
ATOM 7776 C CA  . GLY A 1 1091 ? 83.304  93.863  95.685  1.00 90.46  ? 1091 GLY A CA  1 
ATOM 7777 C C   . GLY A 1 1091 ? 83.226  94.631  94.374  1.00 91.42  ? 1091 GLY A C   1 
ATOM 7778 O O   . GLY A 1 1091 ? 83.443  95.839  94.322  1.00 96.34  ? 1091 GLY A O   1 
ATOM 7779 N N   . ALA A 1 1092 ? 82.932  93.883  93.314  1.00 96.54  ? 1092 ALA A N   1 
ATOM 7780 C CA  . ALA A 1 1092 ? 82.296  94.457  92.149  1.00 113.10 ? 1092 ALA A CA  1 
ATOM 7781 C C   . ALA A 1 1092 ? 81.053  95.181  92.646  1.00 119.39 ? 1092 ALA A C   1 
ATOM 7782 O O   . ALA A 1 1092 ? 80.487  94.781  93.655  1.00 122.25 ? 1092 ALA A O   1 
ATOM 7783 C CB  . ALA A 1 1092 ? 81.955  93.360  91.177  1.00 126.23 ? 1092 ALA A CB  1 
ATOM 7784 N N   . GLU A 1 1093 ? 80.649  96.245  91.951  1.00 137.27 ? 1093 GLU A N   1 
ATOM 7785 C CA  . GLU A 1 1093 ? 79.634  97.162  92.448  1.00 158.80 ? 1093 GLU A CA  1 
ATOM 7786 C C   . GLU A 1 1093 ? 78.393  96.420  92.946  1.00 140.72 ? 1093 GLU A C   1 
ATOM 7787 O O   . GLU A 1 1093 ? 77.825  96.784  93.972  1.00 125.00 ? 1093 GLU A O   1 
ATOM 7788 C CB  . GLU A 1 1093 ? 79.258  98.169  91.355  1.00 191.91 ? 1093 GLU A CB  1 
ATOM 7789 C CG  . GLU A 1 1093 ? 77.990  98.962  91.647  1.00 211.39 ? 1093 GLU A CG  1 
ATOM 7790 C CD  . GLU A 1 1093 ? 77.986  99.751  92.948  1.00 218.56 ? 1093 GLU A CD  1 
ATOM 7791 O OE1 . GLU A 1 1093 ? 78.886  100.597 93.129  1.00 222.71 ? 1093 GLU A OE1 1 
ATOM 7792 O OE2 . GLU A 1 1093 ? 77.069  99.534  93.769  1.00 218.13 ? 1093 GLU A OE2 1 
ATOM 7793 N N   . TYR A 1 1094 ? 77.948  95.406  92.200  1.00 138.03 ? 1094 TYR A N   1 
ATOM 7794 C CA  . TYR A 1 1094 ? 76.685  94.756  92.511  1.00 140.85 ? 1094 TYR A CA  1 
ATOM 7795 C C   . TYR A 1 1094 ? 76.665  94.313  93.975  1.00 137.78 ? 1094 TYR A C   1 
ATOM 7796 O O   . TYR A 1 1094 ? 75.661  94.528  94.648  1.00 138.21 ? 1094 TYR A O   1 
ATOM 7797 C CB  . TYR A 1 1094 ? 76.359  93.657  91.493  1.00 146.12 ? 1094 TYR A CB  1 
ATOM 7798 C CG  . TYR A 1 1094 ? 77.506  92.820  90.983  1.00 156.95 ? 1094 TYR A CG  1 
ATOM 7799 C CD1 . TYR A 1 1094 ? 78.257  92.024  91.832  1.00 173.29 ? 1094 TYR A CD1 1 
ATOM 7800 C CD2 . TYR A 1 1094 ? 77.822  92.795  89.634  1.00 166.83 ? 1094 TYR A CD2 1 
ATOM 7801 C CE1 . TYR A 1 1094 ? 79.294  91.235  91.363  1.00 180.92 ? 1094 TYR A CE1 1 
ATOM 7802 C CE2 . TYR A 1 1094 ? 78.856  92.012  89.147  1.00 176.08 ? 1094 TYR A CE2 1 
ATOM 7803 C CZ  . TYR A 1 1094 ? 79.597  91.231  90.015  1.00 180.86 ? 1094 TYR A CZ  1 
ATOM 7804 O OH  . TYR A 1 1094 ? 80.629  90.449  89.557  1.00 178.88 ? 1094 TYR A OH  1 
ATOM 7805 N N   . ASP A 1 1095 ? 77.785  93.772  94.485  1.00 135.48 ? 1095 ASP A N   1 
ATOM 7806 C CA  . ASP A 1 1095 ? 77.900  93.406  95.892  1.00 126.19 ? 1095 ASP A CA  1 
ATOM 7807 C C   . ASP A 1 1095 ? 78.763  94.424  96.627  1.00 113.71 ? 1095 ASP A C   1 
ATOM 7808 O O   . ASP A 1 1095 ? 79.960  94.521  96.392  1.00 104.25 ? 1095 ASP A O   1 
ATOM 7809 C CB  . ASP A 1 1095 ? 78.560  92.046  96.136  1.00 125.58 ? 1095 ASP A CB  1 
ATOM 7810 C CG  . ASP A 1 1095 ? 77.982  90.890  95.345  1.00 131.80 ? 1095 ASP A CG  1 
ATOM 7811 O OD1 . ASP A 1 1095 ? 76.740  90.763  95.297  1.00 134.17 ? 1095 ASP A OD1 1 
ATOM 7812 O OD2 . ASP A 1 1095 ? 78.787  90.106  94.811  1.00 126.98 ? 1095 ASP A OD2 1 
ATOM 7813 N N   . ASN A 1 1096 ? 78.142  95.158  97.545  1.00 122.02 ? 1096 ASN A N   1 
ATOM 7814 C CA  . ASN A 1 1096 ? 78.865  96.003  98.474  1.00 130.73 ? 1096 ASN A CA  1 
ATOM 7815 C C   . ASN A 1 1096 ? 77.956  96.157  99.689  1.00 117.95 ? 1096 ASN A C   1 
ATOM 7816 O O   . ASN A 1 1096 ? 76.742  96.310  99.548  1.00 125.84 ? 1096 ASN A O   1 
ATOM 7817 C CB  . ASN A 1 1096 ? 79.281  97.330  97.827  1.00 142.41 ? 1096 ASN A CB  1 
ATOM 7818 C CG  . ASN A 1 1096 ? 80.382  98.058  98.571  1.00 153.50 ? 1096 ASN A CG  1 
ATOM 7819 O OD1 . ASN A 1 1096 ? 81.459  98.279  98.022  1.00 149.41 ? 1096 ASN A OD1 1 
ATOM 7820 N ND2 . ASN A 1 1096 ? 80.121  98.443  99.812  1.00 163.14 ? 1096 ASN A ND2 1 
ATOM 7821 N N   . ASN A 1 1097 ? 78.549  96.056  100.877 1.00 89.87  ? 1097 ASN A N   1 
ATOM 7822 C CA  . ASN A 1 1097 ? 77.799  96.164  102.110 1.00 73.61  ? 1097 ASN A CA  1 
ATOM 7823 C C   . ASN A 1 1097 ? 78.774  96.486  103.231 1.00 75.30  ? 1097 ASN A C   1 
ATOM 7824 O O   . ASN A 1 1097 ? 79.974  96.288  103.089 1.00 86.81  ? 1097 ASN A O   1 
ATOM 7825 C CB  . ASN A 1 1097 ? 77.009  94.889  102.393 1.00 73.73  ? 1097 ASN A CB  1 
ATOM 7826 C CG  . ASN A 1 1097 ? 75.671  94.848  101.689 1.00 86.49  ? 1097 ASN A CG  1 
ATOM 7827 O OD1 . ASN A 1 1097 ? 74.746  95.569  102.062 1.00 90.86  ? 1097 ASN A OD1 1 
ATOM 7828 N ND2 . ASN A 1 1097 ? 75.554  93.994  100.683 1.00 93.47  ? 1097 ASN A ND2 1 
ATOM 7829 N N   . LYS A 1 1098 ? 78.244  97.020  104.326 1.00 70.32  ? 1098 LYS A N   1 
ATOM 7830 C CA  . LYS A 1 1098 ? 79.025  97.296  105.515 1.00 64.59  ? 1098 LYS A CA  1 
ATOM 7831 C C   . LYS A 1 1098 ? 78.128  96.939  106.698 1.00 71.34  ? 1098 LYS A C   1 
ATOM 7832 O O   . LYS A 1 1098 ? 76.910  97.092  106.600 1.00 78.71  ? 1098 LYS A O   1 
ATOM 7833 C CB  . LYS A 1 1098 ? 79.473  98.762  105.482 1.00 64.23  ? 1098 LYS A CB  1 
ATOM 7834 C CG  . LYS A 1 1098 ? 80.714  99.092  106.293 1.00 73.80  ? 1098 LYS A CG  1 
ATOM 7835 C CD  . LYS A 1 1098 ? 80.926  100.581 106.507 1.00 88.91  ? 1098 LYS A CD  1 
ATOM 7836 C CE  . LYS A 1 1098 ? 81.312  101.334 105.251 1.00 94.95  ? 1098 LYS A CE  1 
ATOM 7837 N NZ  . LYS A 1 1098 ? 82.705  101.055 104.833 1.00 94.79  ? 1098 LYS A NZ  1 
ATOM 7838 N N   . PHE A 1 1099 ? 78.714  96.413  107.783 1.00 72.84  ? 1099 PHE A N   1 
ATOM 7839 C CA  . PHE A 1 1099 ? 77.960  96.147  108.999 1.00 72.57  ? 1099 PHE A CA  1 
ATOM 7840 C C   . PHE A 1 1099 ? 78.749  96.565  110.233 1.00 64.85  ? 1099 PHE A C   1 
ATOM 7841 O O   . PHE A 1 1099 ? 79.252  95.720  110.959 1.00 65.99  ? 1099 PHE A O   1 
ATOM 7842 C CB  . PHE A 1 1099 ? 77.577  94.677  109.148 1.00 77.20  ? 1099 PHE A CB  1 
ATOM 7843 C CG  . PHE A 1 1099 ? 76.555  94.483  110.234 1.00 106.46 ? 1099 PHE A CG  1 
ATOM 7844 C CD1 . PHE A 1 1099 ? 75.230  94.838  110.015 1.00 145.24 ? 1099 PHE A CD1 1 
ATOM 7845 C CD2 . PHE A 1 1099 ? 76.915  94.016  111.489 1.00 128.62 ? 1099 PHE A CD2 1 
ATOM 7846 C CE1 . PHE A 1 1099 ? 74.279  94.686  111.013 1.00 173.16 ? 1099 PHE A CE1 1 
ATOM 7847 C CE2 . PHE A 1 1099 ? 75.961  93.860  112.486 1.00 162.86 ? 1099 PHE A CE2 1 
ATOM 7848 C CZ  . PHE A 1 1099 ? 74.646  94.199  112.248 1.00 178.13 ? 1099 PHE A CZ  1 
ATOM 7849 N N   . LYS A 1 1100 ? 78.780  97.868  110.504 1.00 66.57  ? 1100 LYS A N   1 
ATOM 7850 C CA  . LYS A 1 1100 ? 79.520  98.388  111.638 1.00 73.63  ? 1100 LYS A CA  1 
ATOM 7851 C C   . LYS A 1 1100 ? 79.027  97.726  112.928 1.00 76.97  ? 1100 LYS A C   1 
ATOM 7852 O O   . LYS A 1 1100 ? 77.851  97.393  113.062 1.00 73.57  ? 1100 LYS A O   1 
ATOM 7853 C CB  . LYS A 1 1100 ? 79.397  99.913  111.704 1.00 86.44  ? 1100 LYS A CB  1 
ATOM 7854 C CG  . LYS A 1 1100 ? 80.435  100.608 112.578 1.00 94.94  ? 1100 LYS A CG  1 
ATOM 7855 C CD  . LYS A 1 1100 ? 80.124  102.064 112.890 1.00 105.88 ? 1100 LYS A CD  1 
ATOM 7856 C CE  . LYS A 1 1100 ? 79.887  102.909 111.656 1.00 115.77 ? 1100 LYS A CE  1 
ATOM 7857 N NZ  . LYS A 1 1100 ? 80.976  102.764 110.660 1.00 117.65 ? 1100 LYS A NZ  1 
ATOM 7858 N N   . THR A 1 1101 ? 79.973  97.529  113.858 1.00 78.49  ? 1101 THR A N   1 
ATOM 7859 C CA  . THR A 1 1101 ? 79.747  96.929  115.161 1.00 74.60  ? 1101 THR A CA  1 
ATOM 7860 C C   . THR A 1 1101 ? 79.804  98.011  116.228 1.00 73.63  ? 1101 THR A C   1 
ATOM 7861 O O   . THR A 1 1101 ? 80.691  98.860  116.173 1.00 75.62  ? 1101 THR A O   1 
ATOM 7862 C CB  . THR A 1 1101 ? 80.864  95.938  115.501 1.00 90.23  ? 1101 THR A CB  1 
ATOM 7863 O OG1 . THR A 1 1101 ? 82.088  96.671  115.411 1.00 81.08  ? 1101 THR A OG1 1 
ATOM 7864 C CG2 . THR A 1 1101 ? 80.911  94.730  114.587 1.00 101.42 ? 1101 THR A CG2 1 
ATOM 7865 N N   . THR A 1 1102 ? 78.935  97.904  117.230 1.00 71.08  ? 1102 THR A N   1 
ATOM 7866 C CA  . THR A 1 1102 ? 78.813  98.946  118.274 1.00 66.47  ? 1102 THR A CA  1 
ATOM 7867 C C   . THR A 1 1102 ? 80.145  99.268  118.906 1.00 50.20  ? 1102 THR A C   1 
ATOM 7868 O O   . THR A 1 1102 ? 80.897  98.381  119.120 1.00 49.67  ? 1102 THR A O   1 
ATOM 7869 C CB  . THR A 1 1102 ? 77.960  98.435  119.422 1.00 72.76  ? 1102 THR A CB  1 
ATOM 7870 O OG1 . THR A 1 1102 ? 78.759  98.511  120.601 1.00 72.46  ? 1102 THR A OG1 1 
ATOM 7871 C CG2 . THR A 1 1102 ? 77.482  97.018  119.206 1.00 81.77  ? 1102 THR A CG2 1 
ATOM 7872 N N   . VAL A 1 1103 ? 80.353  100.505 119.258 1.00 41.82  ? 1103 VAL A N   1 
ATOM 7873 C CA  . VAL A 1 1103 ? 81.629  100.873 119.830 1.00 42.97  ? 1103 VAL A CA  1 
ATOM 7874 C C   . VAL A 1 1103 ? 81.691  100.287 121.232 1.00 47.22  ? 1103 VAL A C   1 
ATOM 7875 O O   . VAL A 1 1103 ? 80.654  100.098 121.867 1.00 60.16  ? 1103 VAL A O   1 
ATOM 7876 C CB  . VAL A 1 1103 ? 81.822  102.400 119.841 1.00 49.58  ? 1103 VAL A CB  1 
ATOM 7877 C CG1 . VAL A 1 1103 ? 83.258  102.794 120.183 1.00 50.57  ? 1103 VAL A CG1 1 
ATOM 7878 C CG2 . VAL A 1 1103 ? 81.392  103.018 118.515 1.00 55.10  ? 1103 VAL A CG2 1 
ATOM 7879 N N   . VAL A 1 1104 ? 82.912  99.995  121.692 1.00 46.55  ? 1104 VAL A N   1 
ATOM 7880 C CA  . VAL A 1 1104 ? 83.176  99.545  123.048 1.00 50.86  ? 1104 VAL A CA  1 
ATOM 7881 C C   . VAL A 1 1104 ? 84.080  100.579 123.715 1.00 59.30  ? 1104 VAL A C   1 
ATOM 7882 O O   . VAL A 1 1104 ? 84.978  101.095 123.073 1.00 61.46  ? 1104 VAL A O   1 
ATOM 7883 C CB  . VAL A 1 1104 ? 83.808  98.138  123.043 1.00 55.20  ? 1104 VAL A CB  1 
ATOM 7884 C CG1 . VAL A 1 1104 ? 84.980  98.016  124.006 1.00 57.77  ? 1104 VAL A CG1 1 
ATOM 7885 C CG2 . VAL A 1 1104 ? 82.766  97.057  123.314 1.00 59.31  ? 1104 VAL A CG2 1 
ATOM 7886 N N   . ASN A 1 1105 ? 83.849  100.875 125.002 1.00 72.81  ? 1105 ASN A N   1 
ATOM 7887 C CA  . ASN A 1 1105 ? 84.582  101.924 125.704 1.00 80.39  ? 1105 ASN A CA  1 
ATOM 7888 C C   . ASN A 1 1105 ? 86.055  101.535 125.753 1.00 74.11  ? 1105 ASN A C   1 
ATOM 7889 O O   . ASN A 1 1105 ? 86.438  100.560 125.125 1.00 73.39  ? 1105 ASN A O   1 
ATOM 7890 C CB  . ASN A 1 1105 ? 83.992  102.169 127.094 1.00 104.38 ? 1105 ASN A CB  1 
ATOM 7891 C CG  . ASN A 1 1105 ? 84.541  103.396 127.793 1.00 129.94 ? 1105 ASN A CG  1 
ATOM 7892 O OD1 . ASN A 1 1105 ? 85.420  104.084 127.280 1.00 123.10 ? 1105 ASN A OD1 1 
ATOM 7893 N ND2 . ASN A 1 1105 ? 84.047  103.667 128.989 1.00 153.13 ? 1105 ASN A ND2 1 
ATOM 7894 N N   . ASP A 1 1106 ? 86.889  102.286 126.480 1.00 83.84  ? 1106 ASP A N   1 
ATOM 7895 C CA  . ASP A 1 1106 ? 88.329  102.059 126.456 1.00 100.19 ? 1106 ASP A CA  1 
ATOM 7896 C C   . ASP A 1 1106 ? 88.664  100.651 126.941 1.00 103.84 ? 1106 ASP A C   1 
ATOM 7897 O O   . ASP A 1 1106 ? 88.161  100.255 127.988 1.00 114.48 ? 1106 ASP A O   1 
ATOM 7898 C CB  . ASP A 1 1106 ? 89.047  103.081 127.335 1.00 110.07 ? 1106 ASP A CB  1 
ATOM 7899 C CG  . ASP A 1 1106 ? 88.852  104.507 126.858 1.00 127.97 ? 1106 ASP A CG  1 
ATOM 7900 O OD1 . ASP A 1 1106 ? 88.083  104.698 125.886 1.00 139.78 ? 1106 ASP A OD1 1 
ATOM 7901 O OD2 . ASP A 1 1106 ? 89.450  105.412 127.469 1.00 133.03 ? 1106 ASP A OD2 1 
ATOM 7902 N N   . ASN A 1 1107 ? 89.500  99.920  126.172 1.00 96.71  ? 1107 ASN A N   1 
ATOM 7903 C CA  . ASN A 1 1107 ? 90.036  98.622  126.565 1.00 95.98  ? 1107 ASN A CA  1 
ATOM 7904 C C   . ASN A 1 1107 ? 90.578  97.892  125.337 1.00 92.36  ? 1107 ASN A C   1 
ATOM 7905 O O   . ASN A 1 1107 ? 89.878  97.090  124.732 1.00 92.38  ? 1107 ASN A O   1 
ATOM 7906 C CB  . ASN A 1 1107 ? 89.039  97.750  127.346 1.00 107.20 ? 1107 ASN A CB  1 
ATOM 7907 C CG  . ASN A 1 1107 ? 87.737  97.444  126.634 1.00 116.26 ? 1107 ASN A CG  1 
ATOM 7908 O OD1 . ASN A 1 1107 ? 86.979  98.339  126.271 1.00 122.25 ? 1107 ASN A OD1 1 
ATOM 7909 N ND2 . ASN A 1 1107 ? 87.433  96.167  126.485 1.00 128.66 ? 1107 ASN A ND2 1 
ATOM 7910 N N   . GLY A 1 1108 ? 91.858  98.129  125.012 1.00 90.17  ? 1108 GLY A N   1 
ATOM 7911 C CA  . GLY A 1 1108 ? 92.497  97.510  123.855 1.00 92.96  ? 1108 GLY A CA  1 
ATOM 7912 C C   . GLY A 1 1108 ? 92.777  96.005  123.969 1.00 90.39  ? 1108 GLY A C   1 
ATOM 7913 O O   . GLY A 1 1108 ? 92.507  95.272  123.021 1.00 87.13  ? 1108 GLY A O   1 
ATOM 7914 N N   . LEU A 1 1109 ? 93.292  95.533  125.106 1.00 71.93  ? 1109 LEU A N   1 
ATOM 7915 C CA  . LEU A 1 1109 ? 93.672  94.096  125.189 1.00 59.07  ? 1109 LEU A CA  1 
ATOM 7916 C C   . LEU A 1 1109 ? 92.460  93.201  124.958 1.00 55.56  ? 1109 LEU A C   1 
ATOM 7917 O O   . LEU A 1 1109 ? 92.608  92.202  124.234 1.00 73.65  ? 1109 LEU A O   1 
ATOM 7918 C CB  . LEU A 1 1109 ? 94.264  93.773  126.559 1.00 57.44  ? 1109 LEU A CB  1 
ATOM 7919 C CG  . LEU A 1 1109 ? 95.704  94.221  126.751 1.00 66.07  ? 1109 LEU A CG  1 
ATOM 7920 C CD1 . LEU A 1 1109 ? 95.708  95.654  127.222 1.00 74.09  ? 1109 LEU A CD1 1 
ATOM 7921 C CD2 . LEU A 1 1109 ? 96.417  93.319  127.744 1.00 70.44  ? 1109 LEU A CD2 1 
ATOM 7922 N N   . SER A 1 1110 ? 91.319  93.524  125.554 1.00 49.47  ? 1110 SER A N   1 
ATOM 7923 C CA  . SER A 1 1110 ? 90.181  92.578  125.447 1.00 58.47  ? 1110 SER A CA  1 
ATOM 7924 C C   . SER A 1 1110 ? 88.881  93.291  125.094 1.00 52.36  ? 1110 SER A C   1 
ATOM 7925 O O   . SER A 1 1110 ? 87.946  93.236  125.905 1.00 74.50  ? 1110 SER A O   1 
ATOM 7926 C CB  . SER A 1 1110 ? 90.028  91.852  126.736 1.00 80.61  ? 1110 SER A CB  1 
ATOM 7927 O OG  . SER A 1 1110 ? 90.206  92.748  127.821 1.00 106.31 ? 1110 SER A OG  1 
ATOM 7928 N N   . PRO A 1 1111 ? 88.756  93.925  123.918 1.00 47.53  ? 1111 PRO A N   1 
ATOM 7929 C CA  . PRO A 1 1111 ? 87.493  94.519  123.545 1.00 51.17  ? 1111 PRO A CA  1 
ATOM 7930 C C   . PRO A 1 1111 ? 86.555  93.349  123.251 1.00 48.59  ? 1111 PRO A C   1 
ATOM 7931 O O   . PRO A 1 1111 ? 86.902  92.535  122.428 1.00 57.16  ? 1111 PRO A O   1 
ATOM 7932 C CB  . PRO A 1 1111 ? 87.818  95.262  122.250 1.00 55.21  ? 1111 PRO A CB  1 
ATOM 7933 C CG  . PRO A 1 1111 ? 89.327  95.340  122.207 1.00 55.64  ? 1111 PRO A CG  1 
ATOM 7934 C CD  . PRO A 1 1111 ? 89.790  94.084  122.907 1.00 57.55  ? 1111 PRO A CD  1 
ATOM 7935 N N   . ILE A 1 1112 ? 85.409  93.287  123.926 1.00 45.93  ? 1112 ILE A N   1 
ATOM 7936 C CA  . ILE A 1 1112 ? 84.494  92.129  123.728 1.00 54.00  ? 1112 ILE A CA  1 
ATOM 7937 C C   . ILE A 1 1112 ? 83.122  92.624  123.272 1.00 52.35  ? 1112 ILE A C   1 
ATOM 7938 O O   . ILE A 1 1112 ? 82.414  93.218  124.100 1.00 57.33  ? 1112 ILE A O   1 
ATOM 7939 C CB  . ILE A 1 1112 ? 84.393  91.290  125.013 1.00 69.30  ? 1112 ILE A CB  1 
ATOM 7940 C CG1 . ILE A 1 1112 ? 85.733  90.626  125.324 1.00 96.60  ? 1112 ILE A CG1 1 
ATOM 7941 C CG2 . ILE A 1 1112 ? 83.277  90.265  124.906 1.00 64.49  ? 1112 ILE A CG2 1 
ATOM 7942 C CD1 . ILE A 1 1112 ? 86.345  89.946  124.124 1.00 106.85 ? 1112 ILE A CD1 1 
ATOM 7943 N N   . TRP A 1 1113 ? 82.767  92.394  122.006 1.00 52.65  ? 1113 TRP A N   1 
ATOM 7944 C CA  . TRP A 1 1113 ? 81.404  92.744  121.537 1.00 50.42  ? 1113 TRP A CA  1 
ATOM 7945 C C   . TRP A 1 1113 ? 80.492  91.593  121.933 1.00 53.78  ? 1113 TRP A C   1 
ATOM 7946 O O   . TRP A 1 1113 ? 79.812  91.035  121.049 1.00 49.34  ? 1113 TRP A O   1 
ATOM 7947 C CB  . TRP A 1 1113 ? 81.373  92.986  120.024 1.00 45.79  ? 1113 TRP A CB  1 
ATOM 7948 C CG  . TRP A 1 1113 ? 82.202  94.154  119.562 1.00 43.45  ? 1113 TRP A CG  1 
ATOM 7949 C CD1 . TRP A 1 1113 ? 81.737  95.373  119.171 1.00 49.28  ? 1113 TRP A CD1 1 
ATOM 7950 C CD2 . TRP A 1 1113 ? 83.635  94.202  119.402 1.00 40.91  ? 1113 TRP A CD2 1 
ATOM 7951 N NE1 . TRP A 1 1113 ? 82.776  96.185  118.806 1.00 48.26  ? 1113 TRP A NE1 1 
ATOM 7952 C CE2 . TRP A 1 1113 ? 83.952  95.493  118.930 1.00 41.20  ? 1113 TRP A CE2 1 
ATOM 7953 C CE3 . TRP A 1 1113 ? 84.675  93.292  119.612 1.00 50.25  ? 1113 TRP A CE3 1 
ATOM 7954 C CZ2 . TRP A 1 1113 ? 85.260  95.890  118.669 1.00 44.62  ? 1113 TRP A CZ2 1 
ATOM 7955 C CZ3 . TRP A 1 1113 ? 85.967  93.687  119.351 1.00 56.54  ? 1113 TRP A CZ3 1 
ATOM 7956 C CH2 . TRP A 1 1113 ? 86.254  94.967  118.887 1.00 50.13  ? 1113 TRP A CH2 1 
ATOM 7957 N N   . ALA A 1 1114 ? 80.495  91.243  123.221 1.00 75.43  ? 1114 ALA A N   1 
ATOM 7958 C CA  . ALA A 1 1114 ? 79.680  90.113  123.719 1.00 105.31 ? 1114 ALA A CA  1 
ATOM 7959 C C   . ALA A 1 1114 ? 78.417  89.992  122.872 1.00 118.87 ? 1114 ALA A C   1 
ATOM 7960 O O   . ALA A 1 1114 ? 77.638  90.958  122.863 1.00 114.92 ? 1114 ALA A O   1 
ATOM 7961 C CB  . ALA A 1 1114 ? 79.336  90.328  125.170 1.00 117.95 ? 1114 ALA A CB  1 
ATOM 7962 N N   . PRO A 1 1115 ? 78.142  88.830  122.244 1.00 152.64 ? 1115 PRO A N   1 
ATOM 7963 C CA  . PRO A 1 1115 ? 77.007  88.666  121.343 1.00 174.08 ? 1115 PRO A CA  1 
ATOM 7964 C C   . PRO A 1 1115 ? 76.039  89.855  121.378 1.00 194.73 ? 1115 PRO A C   1 
ATOM 7965 O O   . PRO A 1 1115 ? 74.954  89.707  121.908 1.00 198.34 ? 1115 PRO A O   1 
ATOM 7966 C CB  . PRO A 1 1115 ? 76.407  87.396  121.956 1.00 177.93 ? 1115 PRO A CB  1 
ATOM 7967 C CG  . PRO A 1 1115 ? 77.632  86.563  122.317 1.00 178.16 ? 1115 PRO A CG  1 
ATOM 7968 C CD  . PRO A 1 1115 ? 78.785  87.540  122.472 1.00 171.01 ? 1115 PRO A CD  1 
ATOM 7969 N N   . THR A 1 1116 ? 76.456  90.995  120.818 1.00 213.05 ? 1116 THR A N   1 
ATOM 7970 C CA  . THR A 1 1116 ? 75.555  92.175  120.738 1.00 223.82 ? 1116 THR A CA  1 
ATOM 7971 C C   . THR A 1 1116 ? 74.807  92.082  119.408 1.00 217.74 ? 1116 THR A C   1 
ATOM 7972 O O   . THR A 1 1116 ? 74.993  92.984  118.567 1.00 218.00 ? 1116 THR A O   1 
ATOM 7973 C CB  . THR A 1 1116 ? 76.334  93.486  120.906 1.00 228.43 ? 1116 THR A CB  1 
ATOM 7974 O OG1 . THR A 1 1116 ? 77.348  93.280  121.891 1.00 218.70 ? 1116 THR A OG1 1 
ATOM 7975 C CG2 . THR A 1 1116 ? 75.454  94.647  121.315 1.00 232.58 ? 1116 THR A CG2 1 
ATOM 7976 N N   . GLN A 1 1117 ? 74.033  91.009  119.222 1.00 204.50 ? 1117 GLN A N   1 
ATOM 7977 C CA  . GLN A 1 1117 ? 73.256  90.808  117.970 1.00 197.73 ? 1117 GLN A CA  1 
ATOM 7978 C C   . GLN A 1 1117 ? 74.216  90.682  116.785 1.00 182.27 ? 1117 GLN A C   1 
ATOM 7979 O O   . GLN A 1 1117 ? 74.381  89.552  116.295 1.00 191.88 ? 1117 GLN A O   1 
ATOM 7980 C CB  . GLN A 1 1117 ? 72.256  91.947  117.753 1.00 210.24 ? 1117 GLN A CB  1 
ATOM 7981 C CG  . GLN A 1 1117 ? 71.495  91.843  116.440 1.00 224.45 ? 1117 GLN A CG  1 
ATOM 7982 C CD  . GLN A 1 1117 ? 70.876  90.480  116.253 1.00 236.66 ? 1117 GLN A CD  1 
ATOM 7983 O OE1 . GLN A 1 1117 ? 70.062  90.031  117.057 1.00 239.68 ? 1117 GLN A OE1 1 
ATOM 7984 N NE2 . GLN A 1 1117 ? 71.264  89.807  115.183 1.00 240.33 ? 1117 GLN A NE2 1 
ATOM 7985 N N   . GLU A 1 1118 ? 74.834  91.787  116.357 1.00 163.50 ? 1118 GLU A N   1 
ATOM 7986 C CA  . GLU A 1 1118 ? 75.688  91.736  115.142 1.00 165.65 ? 1118 GLU A CA  1 
ATOM 7987 C C   . GLU A 1 1118 ? 74.965  90.858  114.117 1.00 167.68 ? 1118 GLU A C   1 
ATOM 7988 O O   . GLU A 1 1118 ? 73.876  91.267  113.670 1.00 179.57 ? 1118 GLU A O   1 
ATOM 7989 C CB  . GLU A 1 1118 ? 77.071  91.187  115.491 1.00 165.30 ? 1118 GLU A CB  1 
ATOM 7990 C CG  . GLU A 1 1118 ? 77.562  91.590  116.870 1.00 166.49 ? 1118 GLU A CG  1 
ATOM 7991 C CD  . GLU A 1 1118 ? 77.982  93.041  117.022 1.00 178.24 ? 1118 GLU A CD  1 
ATOM 7992 O OE1 . GLU A 1 1118 ? 77.923  93.784  116.023 1.00 180.68 ? 1118 GLU A OE1 1 
ATOM 7993 O OE2 . GLU A 1 1118 ? 78.369  93.425  118.142 1.00 185.16 ? 1118 GLU A OE2 1 
ATOM 7994 N N   . LYS A 1 1119 ? 75.542  89.711  113.752 1.00 149.04 ? 1119 LYS A N   1 
ATOM 7995 C CA  . LYS A 1 1119 ? 74.865  88.768  112.871 1.00 135.40 ? 1119 LYS A CA  1 
ATOM 7996 C C   . LYS A 1 1119 ? 74.429  89.432  111.560 1.00 118.36 ? 1119 LYS A C   1 
ATOM 7997 O O   . LYS A 1 1119 ? 73.327  89.189  111.068 1.00 118.58 ? 1119 LYS A O   1 
ATOM 7998 C CB  . LYS A 1 1119 ? 73.685  88.111  113.599 1.00 142.75 ? 1119 LYS A CB  1 
ATOM 7999 C CG  . LYS A 1 1119 ? 73.768  86.595  113.730 1.00 153.30 ? 1119 LYS A CG  1 
ATOM 8000 C CD  . LYS A 1 1119 ? 75.126  86.073  114.168 1.00 159.23 ? 1119 LYS A CD  1 
ATOM 8001 C CE  . LYS A 1 1119 ? 75.112  84.626  114.616 1.00 170.26 ? 1119 LYS A CE  1 
ATOM 8002 N NZ  . LYS A 1 1119 ? 74.735  83.705  113.516 1.00 175.70 ? 1119 LYS A NZ  1 
ATOM 8003 N N   . VAL A 1 1120 ? 75.317  90.260  110.998 1.00 94.78  ? 1120 VAL A N   1 
ATOM 8004 C CA  . VAL A 1 1120 ? 75.229  90.717  109.618 1.00 82.12  ? 1120 VAL A CA  1 
ATOM 8005 C C   . VAL A 1 1120 ? 75.190  89.504  108.690 1.00 79.34  ? 1120 VAL A C   1 
ATOM 8006 O O   . VAL A 1 1120 ? 75.826  88.501  108.992 1.00 80.23  ? 1120 VAL A O   1 
ATOM 8007 C CB  . VAL A 1 1120 ? 76.419  91.632  109.267 1.00 86.32  ? 1120 VAL A CB  1 
ATOM 8008 C CG1 . VAL A 1 1120 ? 77.686  91.294  110.038 1.00 86.50  ? 1120 VAL A CG1 1 
ATOM 8009 C CG2 . VAL A 1 1120 ? 76.724  91.645  107.779 1.00 99.84  ? 1120 VAL A CG2 1 
ATOM 8010 N N   . THR A 1 1121 ? 74.481  89.612  107.551 1.00 81.77  ? 1121 THR A N   1 
ATOM 8011 C CA  . THR A 1 1121 ? 74.477  88.573  106.524 1.00 82.99  ? 1121 THR A CA  1 
ATOM 8012 C C   . THR A 1 1121 ? 74.812  89.155  105.149 1.00 82.35  ? 1121 THR A C   1 
ATOM 8013 O O   . THR A 1 1121 ? 73.948  89.228  104.276 1.00 85.86  ? 1121 THR A O   1 
ATOM 8014 C CB  . THR A 1 1121 ? 73.128  87.849  106.426 1.00 89.70  ? 1121 THR A CB  1 
ATOM 8015 O OG1 . THR A 1 1121 ? 72.131  88.818  106.099 1.00 92.99  ? 1121 THR A OG1 1 
ATOM 8016 C CG2 . THR A 1 1121 ? 72.745  87.131  107.701 1.00 97.99  ? 1121 THR A CG2 1 
ATOM 8017 N N   . PHE A 1 1122 ? 76.083  89.540  104.966 1.00 72.98  ? 1122 PHE A N   1 
ATOM 8018 C CA  . PHE A 1 1122 ? 76.615  89.931  103.671 1.00 65.26  ? 1122 PHE A CA  1 
ATOM 8019 C C   . PHE A 1 1122 ? 76.304  88.847  102.642 1.00 80.30  ? 1122 PHE A C   1 
ATOM 8020 O O   . PHE A 1 1122 ? 76.433  87.668  102.949 1.00 86.74  ? 1122 PHE A O   1 
ATOM 8021 C CB  . PHE A 1 1122 ? 78.119  90.148  103.794 1.00 58.29  ? 1122 PHE A CB  1 
ATOM 8022 C CG  . PHE A 1 1122 ? 78.510  91.398  104.532 1.00 70.64  ? 1122 PHE A CG  1 
ATOM 8023 C CD1 . PHE A 1 1122 ? 77.605  92.437  104.723 1.00 93.25  ? 1122 PHE A CD1 1 
ATOM 8024 C CD2 . PHE A 1 1122 ? 79.793  91.553  105.028 1.00 78.25  ? 1122 PHE A CD2 1 
ATOM 8025 C CE1 . PHE A 1 1122 ? 77.970  93.596  105.401 1.00 111.20 ? 1122 PHE A CE1 1 
ATOM 8026 C CE2 . PHE A 1 1122 ? 80.156  92.712  105.704 1.00 91.96  ? 1122 PHE A CE2 1 
ATOM 8027 C CZ  . PHE A 1 1122 ? 79.247  93.731  105.892 1.00 106.97 ? 1122 PHE A CZ  1 
ATOM 8028 N N   . GLU A 1 1123 ? 75.880  89.254  101.436 1.00 90.74  ? 1123 GLU A N   1 
ATOM 8029 C CA  . GLU A 1 1123 ? 75.501  88.332  100.370 1.00 89.51  ? 1123 GLU A CA  1 
ATOM 8030 C C   . GLU A 1 1123 ? 76.432  88.557  99.179  1.00 91.25  ? 1123 GLU A C   1 
ATOM 8031 O O   . GLU A 1 1123 ? 76.562  89.689  98.719  1.00 98.87  ? 1123 GLU A O   1 
ATOM 8032 C CB  . GLU A 1 1123 ? 74.043  88.580  99.979  1.00 87.37  ? 1123 GLU A CB  1 
ATOM 8033 C CG  . GLU A 1 1123 ? 73.211  87.317  99.896  1.00 98.22  ? 1123 GLU A CG  1 
ATOM 8034 C CD  . GLU A 1 1123 ? 71.734  87.543  99.619  1.00 116.29 ? 1123 GLU A CD  1 
ATOM 8035 O OE1 . GLU A 1 1123 ? 70.968  86.558  99.686  1.00 131.16 ? 1123 GLU A OE1 1 
ATOM 8036 O OE2 . GLU A 1 1123 ? 71.351  88.698  99.332  1.00 118.38 ? 1123 GLU A OE2 1 
ATOM 8037 N N   . ILE A 1 1124 ? 77.090  87.491  98.698  1.00 85.27  ? 1124 ILE A N   1 
ATOM 8038 C CA  . ILE A 1 1124 ? 78.074  87.628  97.637  1.00 89.24  ? 1124 ILE A CA  1 
ATOM 8039 C C   . ILE A 1 1124 ? 77.524  86.970  96.374  1.00 102.71 ? 1124 ILE A C   1 
ATOM 8040 O O   . ILE A 1 1124 ? 77.230  85.779  96.371  1.00 103.91 ? 1124 ILE A O   1 
ATOM 8041 C CB  . ILE A 1 1124 ? 79.444  87.047  98.048  1.00 90.17  ? 1124 ILE A CB  1 
ATOM 8042 C CG1 . ILE A 1 1124 ? 79.834  87.411  99.482  1.00 91.19  ? 1124 ILE A CG1 1 
ATOM 8043 C CG2 . ILE A 1 1124 ? 80.527  87.474  97.069  1.00 99.44  ? 1124 ILE A CG2 1 
ATOM 8044 C CD1 . ILE A 1 1124 ? 79.561  86.322  100.490 1.00 97.35  ? 1124 ILE A CD1 1 
ATOM 8045 N N   . TYR A 1 1125 ? 77.417  87.753  95.293  1.00 114.68 ? 1125 TYR A N   1 
ATOM 8046 C CA  . TYR A 1 1125 ? 76.801  87.293  94.060  1.00 116.78 ? 1125 TYR A CA  1 
ATOM 8047 C C   . TYR A 1 1125 ? 77.746  86.384  93.282  1.00 119.61 ? 1125 TYR A C   1 
ATOM 8048 O O   . TYR A 1 1125 ? 77.317  85.341  92.799  1.00 122.66 ? 1125 TYR A O   1 
ATOM 8049 C CB  . TYR A 1 1125 ? 76.344  88.484  93.216  1.00 122.01 ? 1125 TYR A CB  1 
ATOM 8050 C CG  . TYR A 1 1125 ? 75.034  89.096  93.642  1.00 127.45 ? 1125 TYR A CG  1 
ATOM 8051 C CD1 . TYR A 1 1125 ? 74.179  88.451  94.522  1.00 129.21 ? 1125 TYR A CD1 1 
ATOM 8052 C CD2 . TYR A 1 1125 ? 74.650  90.337  93.164  1.00 136.66 ? 1125 TYR A CD2 1 
ATOM 8053 C CE1 . TYR A 1 1125 ? 72.967  89.010  94.889  1.00 140.76 ? 1125 TYR A CE1 1 
ATOM 8054 C CE2 . TYR A 1 1125 ? 73.447  90.916  93.530  1.00 150.48 ? 1125 TYR A CE2 1 
ATOM 8055 C CZ  . TYR A 1 1125 ? 72.602  90.251  94.399  1.00 153.00 ? 1125 TYR A CZ  1 
ATOM 8056 O OH  . TYR A 1 1125 ? 71.406  90.827  94.766  1.00 160.59 ? 1125 TYR A OH  1 
ATOM 8057 N N   . ASP A 1 1126 ? 79.013  86.795  93.143  1.00 123.69 ? 1126 ASP A N   1 
ATOM 8058 C CA  . ASP A 1 1126 ? 80.009  85.979  92.467  1.00 137.67 ? 1126 ASP A CA  1 
ATOM 8059 C C   . ASP A 1 1126 ? 81.186  85.723  93.404  1.00 126.09 ? 1126 ASP A C   1 
ATOM 8060 O O   . ASP A 1 1126 ? 81.899  86.647  93.776  1.00 120.50 ? 1126 ASP A O   1 
ATOM 8061 C CB  . ASP A 1 1126 ? 80.511  86.626  91.176  1.00 160.34 ? 1126 ASP A CB  1 
ATOM 8062 C CG  . ASP A 1 1126 ? 81.588  85.807  90.483  1.00 178.83 ? 1126 ASP A CG  1 
ATOM 8063 O OD1 . ASP A 1 1126 ? 81.302  84.642  90.135  1.00 186.56 ? 1126 ASP A OD1 1 
ATOM 8064 O OD2 . ASP A 1 1126 ? 82.707  86.333  90.305  1.00 182.14 ? 1126 ASP A OD2 1 
ATOM 8065 N N   . PRO A 1 1127 ? 81.443  84.458  93.798  1.00 115.55 ? 1127 PRO A N   1 
ATOM 8066 C CA  . PRO A 1 1127 ? 82.454  84.175  94.813  1.00 103.29 ? 1127 PRO A CA  1 
ATOM 8067 C C   . PRO A 1 1127 ? 83.879  84.509  94.391  1.00 91.08  ? 1127 PRO A C   1 
ATOM 8068 O O   . PRO A 1 1127 ? 84.633  85.041  95.191  1.00 92.25  ? 1127 PRO A O   1 
ATOM 8069 C CB  . PRO A 1 1127 ? 82.321  82.663  95.049  1.00 116.98 ? 1127 PRO A CB  1 
ATOM 8070 C CG  . PRO A 1 1127 ? 81.702  82.136  93.770  1.00 129.15 ? 1127 PRO A CG  1 
ATOM 8071 C CD  . PRO A 1 1127 ? 80.781  83.243  93.299  1.00 125.73 ? 1127 PRO A CD  1 
ATOM 8072 N N   . ASN A 1 1128 ? 84.232  84.201  93.141  1.00 89.46  ? 1128 ASN A N   1 
ATOM 8073 C CA  . ASN A 1 1128 ? 85.624  83.991  92.780  1.00 97.36  ? 1128 ASN A CA  1 
ATOM 8074 C C   . ASN A 1 1128 ? 86.420  85.293  92.832  1.00 93.96  ? 1128 ASN A C   1 
ATOM 8075 O O   . ASN A 1 1128 ? 87.553  85.284  93.307  1.00 100.07 ? 1128 ASN A O   1 
ATOM 8076 C CB  . ASN A 1 1128 ? 85.742  83.241  91.454  1.00 110.53 ? 1128 ASN A CB  1 
ATOM 8077 C CG  . ASN A 1 1128 ? 85.343  81.790  91.625  1.00 122.03 ? 1128 ASN A CG  1 
ATOM 8078 O OD1 . ASN A 1 1128 ? 85.964  81.066  92.402  1.00 121.50 ? 1128 ASN A OD1 1 
ATOM 8079 N ND2 . ASN A 1 1128 ? 84.295  81.364  90.937  1.00 129.88 ? 1128 ASN A ND2 1 
ATOM 8080 N N   . LEU A 1 1129 ? 85.854  86.408  92.363  1.00 82.59  ? 1129 LEU A N   1 
ATOM 8081 C CA  . LEU A 1 1129 ? 86.433  87.686  92.738  1.00 78.66  ? 1129 LEU A CA  1 
ATOM 8082 C C   . LEU A 1 1129 ? 85.482  88.381  93.699  1.00 77.76  ? 1129 LEU A C   1 
ATOM 8083 O O   . LEU A 1 1129 ? 84.340  88.687  93.371  1.00 84.35  ? 1129 LEU A O   1 
ATOM 8084 C CB  . LEU A 1 1129 ? 86.747  88.551  91.520  1.00 89.26  ? 1129 LEU A CB  1 
ATOM 8085 C CG  . LEU A 1 1129 ? 87.611  89.785  91.806  1.00 98.84  ? 1129 LEU A CG  1 
ATOM 8086 C CD1 . LEU A 1 1129 ? 88.706  89.499  92.838  1.00 86.30  ? 1129 LEU A CD1 1 
ATOM 8087 C CD2 . LEU A 1 1129 ? 88.220  90.308  90.509  1.00 110.69 ? 1129 LEU A CD2 1 
ATOM 8088 N N   . ALA A 1 1130 ? 85.978  88.531  94.924  1.00 74.11  ? 1130 ALA A N   1 
ATOM 8089 C CA  . ALA A 1 1130 ? 85.333  89.257  96.002  1.00 62.79  ? 1130 ALA A CA  1 
ATOM 8090 C C   . ALA A 1 1130 ? 86.419  89.475  97.042  1.00 53.39  ? 1130 ALA A C   1 
ATOM 8091 O O   . ALA A 1 1130 ? 87.552  89.064  96.833  1.00 53.12  ? 1130 ALA A O   1 
ATOM 8092 C CB  . ALA A 1 1130 ? 84.168  88.484  96.573  1.00 57.19  ? 1130 ALA A CB  1 
ATOM 8093 N N   . PHE A 1 1131 ? 86.076  90.115  98.145  1.00 49.06  ? 1131 PHE A N   1 
ATOM 8094 C CA  . PHE A 1 1131 ? 86.985  90.220  99.265  1.00 51.52  ? 1131 PHE A CA  1 
ATOM 8095 C C   . PHE A 1 1131 ? 86.120  90.412  100.507 1.00 56.78  ? 1131 PHE A C   1 
ATOM 8096 O O   . PHE A 1 1131 ? 85.105  91.096  100.429 1.00 71.56  ? 1131 PHE A O   1 
ATOM 8097 C CB  . PHE A 1 1131 ? 87.982  91.362  99.042  1.00 54.98  ? 1131 PHE A CB  1 
ATOM 8098 C CG  . PHE A 1 1131 ? 89.010  91.125  97.968  1.00 64.42  ? 1131 PHE A CG  1 
ATOM 8099 C CD1 . PHE A 1 1131 ? 90.097  90.304  98.205  1.00 79.18  ? 1131 PHE A CD1 1 
ATOM 8100 C CD2 . PHE A 1 1131 ? 88.896  91.714  96.721  1.00 78.53  ? 1131 PHE A CD2 1 
ATOM 8101 C CE1 . PHE A 1 1131 ? 91.043  90.072  97.215  1.00 90.89  ? 1131 PHE A CE1 1 
ATOM 8102 C CE2 . PHE A 1 1131 ? 89.849  91.491  95.735  1.00 95.54  ? 1131 PHE A CE2 1 
ATOM 8103 C CZ  . PHE A 1 1131 ? 90.920  90.661  95.977  1.00 99.71  ? 1131 PHE A CZ  1 
ATOM 8104 N N   . LEU A 1 1132 ? 86.486  89.764  101.620 1.00 46.59  ? 1132 LEU A N   1 
ATOM 8105 C CA  . LEU A 1 1132 ? 85.925  90.063  102.927 1.00 36.38  ? 1132 LEU A CA  1 
ATOM 8106 C C   . LEU A 1 1132 ? 86.913  90.964  103.652 1.00 31.78  ? 1132 LEU A C   1 
ATOM 8107 O O   . LEU A 1 1132 ? 88.038  90.546  103.891 1.00 35.19  ? 1132 LEU A O   1 
ATOM 8108 C CB  . LEU A 1 1132 ? 85.717  88.751  103.675 1.00 35.56  ? 1132 LEU A CB  1 
ATOM 8109 C CG  . LEU A 1 1132 ? 85.110  88.891  105.064 1.00 44.02  ? 1132 LEU A CG  1 
ATOM 8110 C CD1 . LEU A 1 1132 ? 83.671  89.369  104.980 1.00 47.43  ? 1132 LEU A CD1 1 
ATOM 8111 C CD2 . LEU A 1 1132 ? 85.192  87.565  105.816 1.00 48.77  ? 1132 LEU A CD2 1 
ATOM 8112 N N   . ARG A 1 1133 ? 86.523  92.210  103.916 1.00 28.55  ? 1133 ARG A N   1 
ATOM 8113 C CA  . ARG A 1 1133 ? 87.427  93.160  104.532 1.00 29.99  ? 1133 ARG A CA  1 
ATOM 8114 C C   . ARG A 1 1133 ? 86.922  93.451  105.943 1.00 36.59  ? 1133 ARG A C   1 
ATOM 8115 O O   . ARG A 1 1133 ? 85.783  93.865  106.103 1.00 44.88  ? 1133 ARG A O   1 
ATOM 8116 C CB  . ARG A 1 1133 ? 87.540  94.414  103.667 1.00 27.20  ? 1133 ARG A CB  1 
ATOM 8117 C CG  . ARG A 1 1133 ? 88.462  95.493  104.226 1.00 25.70  ? 1133 ARG A CG  1 
ATOM 8118 C CD  . ARG A 1 1133 ? 88.438  96.717  103.331 1.00 25.90  ? 1133 ARG A CD  1 
ATOM 8119 N NE  . ARG A 1 1133 ? 89.232  97.828  103.813 1.00 26.50  ? 1133 ARG A NE  1 
ATOM 8120 C CZ  . ARG A 1 1133 ? 90.557  97.816  103.902 1.00 30.15  ? 1133 ARG A CZ  1 
ATOM 8121 N NH1 . ARG A 1 1133 ? 91.244  96.727  103.591 1.00 31.53  ? 1133 ARG A NH1 1 
ATOM 8122 N NH2 . ARG A 1 1133 ? 91.196  98.906  104.296 1.00 30.54  ? 1133 ARG A NH2 1 
ATOM 8123 N N   . PHE A 1 1134 ? 87.734  93.120  106.958 1.00 35.56  ? 1134 PHE A N   1 
ATOM 8124 C CA  . PHE A 1 1134 ? 87.493  93.496  108.339 1.00 32.54  ? 1134 PHE A CA  1 
ATOM 8125 C C   . PHE A 1 1134 ? 88.423  94.650  108.680 1.00 35.32  ? 1134 PHE A C   1 
ATOM 8126 O O   . PHE A 1 1134 ? 89.630  94.481  108.558 1.00 38.97  ? 1134 PHE A O   1 
ATOM 8127 C CB  . PHE A 1 1134 ? 87.845  92.349  109.287 1.00 31.06  ? 1134 PHE A CB  1 
ATOM 8128 C CG  . PHE A 1 1134 ? 87.003  91.107  109.192 1.00 31.53  ? 1134 PHE A CG  1 
ATOM 8129 C CD1 . PHE A 1 1134 ? 85.685  91.121  109.595 1.00 35.38  ? 1134 PHE A CD1 1 
ATOM 8130 C CD2 . PHE A 1 1134 ? 87.538  89.901  108.792 1.00 31.67  ? 1134 PHE A CD2 1 
ATOM 8131 C CE1 . PHE A 1 1134 ? 84.908  89.976  109.545 1.00 35.05  ? 1134 PHE A CE1 1 
ATOM 8132 C CE2 . PHE A 1 1134 ? 86.756  88.754  108.748 1.00 32.59  ? 1134 PHE A CE2 1 
ATOM 8133 C CZ  . PHE A 1 1134 ? 85.441  88.791  109.122 1.00 31.80  ? 1134 PHE A CZ  1 
ATOM 8134 N N   . VAL A 1 1135 ? 87.875  95.796  109.101 1.00 35.96  ? 1135 VAL A N   1 
ATOM 8135 C CA  . VAL A 1 1135 ? 88.695  96.915  109.542 1.00 40.52  ? 1135 VAL A CA  1 
ATOM 8136 C C   . VAL A 1 1135 ? 88.287  97.300  110.955 1.00 47.58  ? 1135 VAL A C   1 
ATOM 8137 O O   . VAL A 1 1135 ? 87.100  97.395  111.243 1.00 54.19  ? 1135 VAL A O   1 
ATOM 8138 C CB  . VAL A 1 1135 ? 88.538  98.121  108.615 1.00 47.34  ? 1135 VAL A CB  1 
ATOM 8139 C CG1 . VAL A 1 1135 ? 89.426  98.002  107.397 1.00 52.69  ? 1135 VAL A CG1 1 
ATOM 8140 C CG2 . VAL A 1 1135 ? 87.079  98.315  108.214 1.00 56.71  ? 1135 VAL A CG2 1 
ATOM 8141 N N   . VAL A 1 1136 ? 89.272  97.515  111.829 1.00 49.93  ? 1136 VAL A N   1 
ATOM 8142 C CA  . VAL A 1 1136 ? 88.992  97.969  113.176 1.00 53.60  ? 1136 VAL A CA  1 
ATOM 8143 C C   . VAL A 1 1136 ? 89.464  99.414  113.299 1.00 63.02  ? 1136 VAL A C   1 
ATOM 8144 O O   . VAL A 1 1136 ? 90.651  99.691  113.182 1.00 61.27  ? 1136 VAL A O   1 
ATOM 8145 C CB  . VAL A 1 1136 ? 89.662  97.071  114.220 1.00 57.62  ? 1136 VAL A CB  1 
ATOM 8146 C CG1 . VAL A 1 1136 ? 89.189  97.402  115.630 1.00 64.67  ? 1136 VAL A CG1 1 
ATOM 8147 C CG2 . VAL A 1 1136 ? 89.438  95.612  113.881 1.00 57.49  ? 1136 VAL A CG2 1 
ATOM 8148 N N   . TYR A 1 1137 ? 88.490  100.308 113.523 1.00 67.14  ? 1137 TYR A N   1 
ATOM 8149 C CA  . TYR A 1 1137 ? 88.675  101.750 113.606 1.00 60.66  ? 1137 TYR A CA  1 
ATOM 8150 C C   . TYR A 1 1137 ? 88.407  102.238 115.026 1.00 62.81  ? 1137 TYR A C   1 
ATOM 8151 O O   . TYR A 1 1137 ? 87.325  102.004 115.556 1.00 55.35  ? 1137 TYR A O   1 
ATOM 8152 C CB  . TYR A 1 1137 ? 87.622  102.503 112.792 1.00 59.93  ? 1137 TYR A CB  1 
ATOM 8153 C CG  . TYR A 1 1137 ? 87.808  102.579 111.302 1.00 64.12  ? 1137 TYR A CG  1 
ATOM 8154 C CD1 . TYR A 1 1137 ? 88.960  103.108 110.747 1.00 74.04  ? 1137 TYR A CD1 1 
ATOM 8155 C CD2 . TYR A 1 1137 ? 86.789  102.197 110.449 1.00 62.07  ? 1137 TYR A CD2 1 
ATOM 8156 C CE1 . TYR A 1 1137 ? 89.109  103.220 109.375 1.00 92.86  ? 1137 TYR A CE1 1 
ATOM 8157 C CE2 . TYR A 1 1137 ? 86.922  102.303 109.078 1.00 74.72  ? 1137 TYR A CE2 1 
ATOM 8158 C CZ  . TYR A 1 1137 ? 88.090  102.804 108.535 1.00 96.72  ? 1137 TYR A CZ  1 
ATOM 8159 O OH  . TYR A 1 1137 ? 88.224  102.898 107.166 1.00 107.43 ? 1137 TYR A OH  1 
ATOM 8160 N N   . GLU A 1 1138 ? 89.371  102.977 115.589 1.00 71.51  ? 1138 GLU A N   1 
ATOM 8161 C CA  . GLU A 1 1138 ? 89.216  103.677 116.857 1.00 78.66  ? 1138 GLU A CA  1 
ATOM 8162 C C   . GLU A 1 1138 ? 88.296  104.889 116.697 1.00 85.18  ? 1138 GLU A C   1 
ATOM 8163 O O   . GLU A 1 1138 ? 88.285  105.513 115.648 1.00 101.78 ? 1138 GLU A O   1 
ATOM 8164 C CB  . GLU A 1 1138 ? 90.599  104.091 117.365 1.00 79.36  ? 1138 GLU A CB  1 
ATOM 8165 C CG  . GLU A 1 1138 ? 90.668  105.481 117.970 1.00 90.66  ? 1138 GLU A CG  1 
ATOM 8166 C CD  . GLU A 1 1138 ? 92.083  105.871 118.362 1.00 113.75 ? 1138 GLU A CD  1 
ATOM 8167 O OE1 . GLU A 1 1138 ? 92.279  107.011 118.836 1.00 134.67 ? 1138 GLU A OE1 1 
ATOM 8168 O OE2 . GLU A 1 1138 ? 92.989  105.032 118.191 1.00 119.01 ? 1138 GLU A OE2 1 
ATOM 8169 N N   . GLU A 1 1139 ? 87.545  105.222 117.752 1.00 81.35  ? 1139 GLU A N   1 
ATOM 8170 C CA  . GLU A 1 1139 ? 86.764  106.449 117.827 1.00 75.53  ? 1139 GLU A CA  1 
ATOM 8171 C C   . GLU A 1 1139 ? 87.415  107.332 118.890 1.00 81.10  ? 1139 GLU A C   1 
ATOM 8172 O O   . GLU A 1 1139 ? 87.496  106.915 120.043 1.00 96.15  ? 1139 GLU A O   1 
ATOM 8173 C CB  . GLU A 1 1139 ? 85.327  106.087 118.211 1.00 77.19  ? 1139 GLU A CB  1 
ATOM 8174 C CG  . GLU A 1 1139 ? 84.262  106.783 117.385 1.00 90.42  ? 1139 GLU A CG  1 
ATOM 8175 C CD  . GLU A 1 1139 ? 82.823  106.512 117.808 1.00 99.17  ? 1139 GLU A CD  1 
ATOM 8176 O OE1 . GLU A 1 1139 ? 82.609  106.083 118.965 1.00 97.56  ? 1139 GLU A OE1 1 
ATOM 8177 O OE2 . GLU A 1 1139 ? 81.909  106.742 116.980 1.00 98.65  ? 1139 GLU A OE2 1 
ATOM 8178 N N   . ASP A 1 1140 ? 87.919  108.518 118.529 1.00 81.62  ? 1140 ASP A N   1 
ATOM 8179 C CA  . ASP A 1 1140 ? 88.701  109.288 119.488 1.00 98.27  ? 1140 ASP A CA  1 
ATOM 8180 C C   . ASP A 1 1140 ? 88.153  110.704 119.641 1.00 96.53  ? 1140 ASP A C   1 
ATOM 8181 O O   . ASP A 1 1140 ? 88.002  111.423 118.659 1.00 101.13 ? 1140 ASP A O   1 
ATOM 8182 C CB  . ASP A 1 1140 ? 90.186  109.310 119.119 1.00 116.77 ? 1140 ASP A CB  1 
ATOM 8183 C CG  . ASP A 1 1140 ? 90.557  110.311 118.039 1.00 134.74 ? 1140 ASP A CG  1 
ATOM 8184 O OD1 . ASP A 1 1140 ? 89.965  110.237 116.952 1.00 144.03 ? 1140 ASP A OD1 1 
ATOM 8185 O OD2 . ASP A 1 1140 ? 91.431  111.165 118.302 1.00 141.92 ? 1140 ASP A OD2 1 
ATOM 8186 N N   . MET A 1 1141 ? 87.880  111.093 120.894 1.00 98.61  ? 1141 MET A N   1 
ATOM 8187 C CA  . MET A 1 1141 ? 87.497  112.456 121.234 1.00 98.85  ? 1141 MET A CA  1 
ATOM 8188 C C   . MET A 1 1141 ? 86.344  112.902 120.333 1.00 94.07  ? 1141 MET A C   1 
ATOM 8189 O O   . MET A 1 1141 ? 85.387  112.151 120.148 1.00 96.74  ? 1141 MET A O   1 
ATOM 8190 C CB  . MET A 1 1141 ? 88.711  113.381 121.103 1.00 102.77 ? 1141 MET A CB  1 
ATOM 8191 C CG  . MET A 1 1141 ? 89.193  113.939 122.428 1.00 112.91 ? 1141 MET A CG  1 
ATOM 8192 S SD  . MET A 1 1141 ? 90.988  114.183 122.488 1.00 133.41 ? 1141 MET A SD  1 
ATOM 8193 C CE  . MET A 1 1141 ? 91.555  112.597 121.871 1.00 144.34 ? 1141 MET A CE  1 
ATOM 8194 N N   . PHE A 1 1142 ? 86.401  114.142 119.825 1.00 83.69  ? 1142 PHE A N   1 
ATOM 8195 C CA  . PHE A 1 1142 ? 85.603  114.521 118.672 1.00 79.32  ? 1142 PHE A CA  1 
ATOM 8196 C C   . PHE A 1 1142 ? 85.463  113.293 117.787 1.00 83.27  ? 1142 PHE A C   1 
ATOM 8197 O O   . PHE A 1 1142 ? 86.479  112.753 117.366 1.00 96.35  ? 1142 PHE A O   1 
ATOM 8198 C CB  . PHE A 1 1142 ? 86.276  115.631 117.861 1.00 78.54  ? 1142 PHE A CB  1 
ATOM 8199 C CG  . PHE A 1 1142 ? 87.488  116.249 118.509 1.00 83.16  ? 1142 PHE A CG  1 
ATOM 8200 C CD1 . PHE A 1 1142 ? 88.721  115.623 118.443 1.00 84.87  ? 1142 PHE A CD1 1 
ATOM 8201 C CD2 . PHE A 1 1142 ? 87.391  117.436 119.214 1.00 93.65  ? 1142 PHE A CD2 1 
ATOM 8202 C CE1 . PHE A 1 1142 ? 89.837  116.186 119.050 1.00 89.07  ? 1142 PHE A CE1 1 
ATOM 8203 C CE2 . PHE A 1 1142 ? 88.505  117.993 119.824 1.00 99.46  ? 1142 PHE A CE2 1 
ATOM 8204 C CZ  . PHE A 1 1142 ? 89.730  117.373 119.737 1.00 94.01  ? 1142 PHE A CZ  1 
ATOM 8205 N N   . SER A 1 1143 ? 84.227  112.853 117.523 1.00 89.60  ? 1143 SER A N   1 
ATOM 8206 C CA  . SER A 1 1143 ? 83.990  111.550 116.916 1.00 99.54  ? 1143 SER A CA  1 
ATOM 8207 C C   . SER A 1 1143 ? 84.378  111.526 115.435 1.00 110.89 ? 1143 SER A C   1 
ATOM 8208 O O   . SER A 1 1143 ? 83.545  111.806 114.572 1.00 113.65 ? 1143 SER A O   1 
ATOM 8209 C CB  . SER A 1 1143 ? 82.559  111.125 117.087 1.00 100.91 ? 1143 SER A CB  1 
ATOM 8210 O OG  . SER A 1 1143 ? 82.240  110.085 116.171 1.00 101.40 ? 1143 SER A OG  1 
ATOM 8211 N N   . ASP A 1 1144 ? 85.645  111.172 115.170 1.00 114.38 ? 1144 ASP A N   1 
ATOM 8212 C CA  . ASP A 1 1144 ? 86.135  110.836 113.842 1.00 113.47 ? 1144 ASP A CA  1 
ATOM 8213 C C   . ASP A 1 1144 ? 86.680  109.414 113.860 1.00 99.21  ? 1144 ASP A C   1 
ATOM 8214 O O   . ASP A 1 1144 ? 87.619  109.136 114.593 1.00 109.63 ? 1144 ASP A O   1 
ATOM 8215 C CB  . ASP A 1 1144 ? 87.336  111.682 113.406 1.00 129.20 ? 1144 ASP A CB  1 
ATOM 8216 C CG  . ASP A 1 1144 ? 87.143  113.187 113.332 1.00 153.47 ? 1144 ASP A CG  1 
ATOM 8217 O OD1 . ASP A 1 1144 ? 85.986  113.659 113.428 1.00 163.66 ? 1144 ASP A OD1 1 
ATOM 8218 O OD2 . ASP A 1 1144 ? 88.172  113.881 113.172 1.00 167.23 ? 1144 ASP A OD2 1 
ATOM 8219 N N   . PRO A 1 1145 ? 86.161  108.471 113.048 1.00 78.84  ? 1145 PRO A N   1 
ATOM 8220 C CA  . PRO A 1 1145 ? 86.859  107.210 112.827 1.00 69.91  ? 1145 PRO A CA  1 
ATOM 8221 C C   . PRO A 1 1145 ? 88.323  107.495 112.490 1.00 64.04  ? 1145 PRO A C   1 
ATOM 8222 O O   . PRO A 1 1145 ? 88.619  108.412 111.735 1.00 70.10  ? 1145 PRO A O   1 
ATOM 8223 C CB  . PRO A 1 1145 ? 86.074  106.573 111.674 1.00 74.53  ? 1145 PRO A CB  1 
ATOM 8224 C CG  . PRO A 1 1145 ? 84.677  107.127 111.850 1.00 77.24  ? 1145 PRO A CG  1 
ATOM 8225 C CD  . PRO A 1 1145 ? 84.885  108.545 112.333 1.00 78.86  ? 1145 PRO A CD  1 
ATOM 8226 N N   . ASN A 1 1146 ? 89.213  106.741 113.135 1.00 61.27  ? 1146 ASN A N   1 
ATOM 8227 C CA  . ASN A 1 1146 ? 90.642  106.713 112.883 1.00 65.40  ? 1146 ASN A CA  1 
ATOM 8228 C C   . ASN A 1 1146 ? 90.992  105.238 112.646 1.00 82.10  ? 1146 ASN A C   1 
ATOM 8229 O O   . ASN A 1 1146 ? 90.233  104.378 113.083 1.00 88.49  ? 1146 ASN A O   1 
ATOM 8230 C CB  . ASN A 1 1146 ? 91.366  107.334 114.078 1.00 65.95  ? 1146 ASN A CB  1 
ATOM 8231 C CG  . ASN A 1 1146 ? 92.654  108.037 113.723 1.00 82.53  ? 1146 ASN A CG  1 
ATOM 8232 O OD1 . ASN A 1 1146 ? 92.850  109.192 114.095 1.00 99.38  ? 1146 ASN A OD1 1 
ATOM 8233 N ND2 . ASN A 1 1146 ? 93.546  107.353 113.027 1.00 88.26  ? 1146 ASN A ND2 1 
ATOM 8234 N N   . PHE A 1 1147 ? 92.120  104.926 111.983 1.00 88.94  ? 1147 PHE A N   1 
ATOM 8235 C CA  . PHE A 1 1147 ? 92.386  103.582 111.464 1.00 85.72  ? 1147 PHE A CA  1 
ATOM 8236 C C   . PHE A 1 1147 ? 93.540  102.878 112.186 1.00 81.98  ? 1147 PHE A C   1 
ATOM 8237 O O   . PHE A 1 1147 ? 94.683  103.326 112.103 1.00 70.80  ? 1147 PHE A O   1 
ATOM 8238 C CB  . PHE A 1 1147 ? 92.722  103.677 109.974 1.00 86.26  ? 1147 PHE A CB  1 
ATOM 8239 C CG  . PHE A 1 1147 ? 92.904  102.366 109.251 1.00 75.99  ? 1147 PHE A CG  1 
ATOM 8240 C CD1 . PHE A 1 1147 ? 91.812  101.578 108.921 1.00 68.75  ? 1147 PHE A CD1 1 
ATOM 8241 C CD2 . PHE A 1 1147 ? 94.168  101.928 108.885 1.00 70.20  ? 1147 PHE A CD2 1 
ATOM 8242 C CE1 . PHE A 1 1147 ? 91.979  100.394 108.225 1.00 65.49  ? 1147 PHE A CE1 1 
ATOM 8243 C CE2 . PHE A 1 1147 ? 94.331  100.737 108.198 1.00 64.71  ? 1147 PHE A CE2 1 
ATOM 8244 C CZ  . PHE A 1 1147 ? 93.238  99.971  107.877 1.00 63.29  ? 1147 PHE A CZ  1 
ATOM 8245 N N   . LEU A 1 1148 ? 93.233  101.717 112.800 1.00 82.51  ? 1148 LEU A N   1 
ATOM 8246 C CA  . LEU A 1 1148 ? 94.182  100.905 113.555 1.00 75.17  ? 1148 LEU A CA  1 
ATOM 8247 C C   . LEU A 1 1148 ? 94.710  99.731  112.729 1.00 70.27  ? 1148 LEU A C   1 
ATOM 8248 O O   . LEU A 1 1148 ? 95.926  99.533  112.684 1.00 79.70  ? 1148 LEU A O   1 
ATOM 8249 C CB  . LEU A 1 1148 ? 93.487  100.360 114.804 1.00 80.92  ? 1148 LEU A CB  1 
ATOM 8250 C CG  . LEU A 1 1148 ? 92.905  101.402 115.758 1.00 97.71  ? 1148 LEU A CG  1 
ATOM 8251 C CD1 . LEU A 1 1148 ? 91.815  100.780 116.625 1.00 101.94 ? 1148 LEU A CD1 1 
ATOM 8252 C CD2 . LEU A 1 1148 ? 93.990  102.031 116.633 1.00 102.23 ? 1148 LEU A CD2 1 
ATOM 8253 N N   . ALA A 1 1149 ? 93.813  98.920  112.138 1.00 55.09  ? 1149 ALA A N   1 
ATOM 8254 C CA  . ALA A 1 1149 ? 94.237  97.677  111.511 1.00 48.13  ? 1149 ALA A CA  1 
ATOM 8255 C C   . ALA A 1 1149 ? 93.167  97.108  110.584 1.00 43.79  ? 1149 ALA A C   1 
ATOM 8256 O O   . ALA A 1 1149 ? 91.985  97.241  110.866 1.00 51.68  ? 1149 ALA A O   1 
ATOM 8257 C CB  . ALA A 1 1149 ? 94.568  96.687  112.594 1.00 53.07  ? 1149 ALA A CB  1 
ATOM 8258 N N   . HIS A 1 1150 ? 93.594  96.463  109.488 1.00 40.32  ? 1150 HIS A N   1 
ATOM 8259 C CA  . HIS A 1 1150 ? 92.706  95.941  108.453 1.00 40.69  ? 1150 HIS A CA  1 
ATOM 8260 C C   . HIS A 1 1150 ? 93.029  94.488  108.154 1.00 34.98  ? 1150 HIS A C   1 
ATOM 8261 O O   . HIS A 1 1150 ? 94.187  94.138  107.994 1.00 36.99  ? 1150 HIS A O   1 
ATOM 8262 C CB  . HIS A 1 1150 ? 92.873  96.661  107.099 1.00 48.79  ? 1150 HIS A CB  1 
ATOM 8263 C CG  . HIS A 1 1150 ? 94.160  96.361  106.407 1.00 53.28  ? 1150 HIS A CG  1 
ATOM 8264 N ND1 . HIS A 1 1150 ? 94.207  95.537  105.308 1.00 52.73  ? 1150 HIS A ND1 1 
ATOM 8265 C CD2 . HIS A 1 1150 ? 95.433  96.716  106.679 1.00 55.90  ? 1150 HIS A CD2 1 
ATOM 8266 C CE1 . HIS A 1 1150 ? 95.471  95.415  104.928 1.00 62.88  ? 1150 HIS A CE1 1 
ATOM 8267 N NE2 . HIS A 1 1150 ? 96.231  96.129  105.741 1.00 59.84  ? 1150 HIS A NE2 1 
ATOM 8268 N N   . ALA A 1 1151 ? 92.003  93.655  108.023 1.00 36.60  ? 1151 ALA A N   1 
ATOM 8269 C CA  . ALA A 1 1151 ? 92.207  92.312  107.512 1.00 42.15  ? 1151 ALA A CA  1 
ATOM 8270 C C   . ALA A 1 1151 ? 91.514  92.188  106.159 1.00 44.47  ? 1151 ALA A C   1 
ATOM 8271 O O   . ALA A 1 1151 ? 90.329  92.481  106.056 1.00 53.29  ? 1151 ALA A O   1 
ATOM 8272 C CB  . ALA A 1 1151 ? 91.674  91.305  108.501 1.00 40.82  ? 1151 ALA A CB  1 
ATOM 8273 N N   . THR A 1 1152 ? 92.244  91.750  105.129 1.00 39.64  ? 1152 THR A N   1 
ATOM 8274 C CA  . THR A 1 1152 ? 91.670  91.564  103.804 1.00 37.89  ? 1152 THR A CA  1 
ATOM 8275 C C   . THR A 1 1152 ? 91.883  90.120  103.374 1.00 32.81  ? 1152 THR A C   1 
ATOM 8276 O O   . THR A 1 1152 ? 92.991  89.617  103.507 1.00 37.01  ? 1152 THR A O   1 
ATOM 8277 C CB  . THR A 1 1152 ? 92.330  92.522  102.805 1.00 48.96  ? 1152 THR A CB  1 
ATOM 8278 O OG1 . THR A 1 1152 ? 92.588  93.766  103.463 1.00 53.55  ? 1152 THR A OG1 1 
ATOM 8279 C CG2 . THR A 1 1152 ? 91.479  92.758  101.575 1.00 58.80  ? 1152 THR A CG2 1 
ATOM 8280 N N   . TYR A 1 1153 ? 90.848  89.451  102.864 1.00 29.59  ? 1153 TYR A N   1 
ATOM 8281 C CA  . TYR A 1 1153 ? 90.956  88.029  102.558 1.00 32.25  ? 1153 TYR A CA  1 
ATOM 8282 C C   . TYR A 1 1153 ? 90.103  87.697  101.342 1.00 27.79  ? 1153 TYR A C   1 
ATOM 8283 O O   . TYR A 1 1153 ? 88.904  87.908  101.378 1.00 31.31  ? 1153 TYR A O   1 
ATOM 8284 C CB  . TYR A 1 1153 ? 90.511  87.155  103.751 1.00 40.39  ? 1153 TYR A CB  1 
ATOM 8285 C CG  . TYR A 1 1153 ? 91.491  87.128  104.895 1.00 49.67  ? 1153 TYR A CG  1 
ATOM 8286 C CD1 . TYR A 1 1153 ? 92.756  86.604  104.697 1.00 62.59  ? 1153 TYR A CD1 1 
ATOM 8287 C CD2 . TYR A 1 1153 ? 91.205  87.667  106.139 1.00 52.90  ? 1153 TYR A CD2 1 
ATOM 8288 C CE1 . TYR A 1 1153 ? 93.717  86.607  105.696 1.00 69.51  ? 1153 TYR A CE1 1 
ATOM 8289 C CE2 . TYR A 1 1153 ? 92.159  87.685  107.147 1.00 60.81  ? 1153 TYR A CE2 1 
ATOM 8290 C CZ  . TYR A 1 1153 ? 93.425  87.161  106.926 1.00 67.22  ? 1153 TYR A CZ  1 
ATOM 8291 O OH  . TYR A 1 1153 ? 94.417  87.148  107.885 1.00 70.89  ? 1153 TYR A OH  1 
ATOM 8292 N N   . PRO A 1 1154 ? 90.657  87.131  100.258 1.00 27.01  ? 1154 PRO A N   1 
ATOM 8293 C CA  . PRO A 1 1154 ? 89.844  86.693  99.134  1.00 27.04  ? 1154 PRO A CA  1 
ATOM 8294 C C   . PRO A 1 1154 ? 88.877  85.636  99.609  1.00 27.31  ? 1154 PRO A C   1 
ATOM 8295 O O   . PRO A 1 1154 ? 89.279  84.774  100.367 1.00 27.43  ? 1154 PRO A O   1 
ATOM 8296 C CB  . PRO A 1 1154 ? 90.818  86.070  98.145  1.00 31.72  ? 1154 PRO A CB  1 
ATOM 8297 C CG  . PRO A 1 1154 ? 92.184  86.589  98.579  1.00 34.46  ? 1154 PRO A CG  1 
ATOM 8298 C CD  . PRO A 1 1154 ? 92.079  86.855  100.067 1.00 31.91  ? 1154 PRO A CD  1 
ATOM 8299 N N   . ILE A 1 1155 ? 87.622  85.739  99.162  1.00 35.73  ? 1155 ILE A N   1 
ATOM 8300 C CA  . ILE A 1 1155 ? 86.508  85.022  99.765  1.00 44.58  ? 1155 ILE A CA  1 
ATOM 8301 C C   . ILE A 1 1155 ? 86.731  83.511  99.697  1.00 56.65  ? 1155 ILE A C   1 
ATOM 8302 O O   . ILE A 1 1155 ? 86.358  82.809  100.633 1.00 65.11  ? 1155 ILE A O   1 
ATOM 8303 C CB  . ILE A 1 1155 ? 85.168  85.436  99.127  1.00 46.26  ? 1155 ILE A CB  1 
ATOM 8304 C CG1 . ILE A 1 1155 ? 84.474  86.549  99.912  1.00 52.90  ? 1155 ILE A CG1 1 
ATOM 8305 C CG2 . ILE A 1 1155 ? 84.246  84.236  98.975  1.00 45.53  ? 1155 ILE A CG2 1 
ATOM 8306 C CD1 . ILE A 1 1155 ? 83.645  86.051  101.089 1.00 59.43  ? 1155 ILE A CD1 1 
ATOM 8307 N N   . LYS A 1 1156 ? 87.330  83.015  98.608  1.00 62.68  ? 1156 LYS A N   1 
ATOM 8308 C CA  . LYS A 1 1156 ? 87.599  81.592  98.476  1.00 70.62  ? 1156 LYS A CA  1 
ATOM 8309 C C   . LYS A 1 1156 ? 88.281  81.068  99.737  1.00 69.08  ? 1156 LYS A C   1 
ATOM 8310 O O   . LYS A 1 1156 ? 87.884  80.029  100.261 1.00 76.24  ? 1156 LYS A O   1 
ATOM 8311 C CB  . LYS A 1 1156 ? 88.486  81.310  97.259  1.00 93.42  ? 1156 LYS A CB  1 
ATOM 8312 C CG  . LYS A 1 1156 ? 87.785  81.384  95.906  1.00 112.43 ? 1156 LYS A CG  1 
ATOM 8313 C CD  . LYS A 1 1156 ? 88.626  80.884  94.735  1.00 113.73 ? 1156 LYS A CD  1 
ATOM 8314 C CE  . LYS A 1 1156 ? 89.893  81.688  94.522  1.00 106.55 ? 1156 LYS A CE  1 
ATOM 8315 N NZ  . LYS A 1 1156 ? 90.717  81.143  93.418  1.00 104.32 ? 1156 LYS A NZ  1 
ATOM 8316 N N   . ALA A 1 1157 ? 89.296  81.798  100.225 1.00 65.60  ? 1157 ALA A N   1 
ATOM 8317 C CA  . ALA A 1 1157 ? 90.055  81.393  101.401 1.00 64.89  ? 1157 ALA A CA  1 
ATOM 8318 C C   . ALA A 1 1157 ? 89.427  81.961  102.674 1.00 62.17  ? 1157 ALA A C   1 
ATOM 8319 O O   . ALA A 1 1157 ? 90.037  82.777  103.365 1.00 65.50  ? 1157 ALA A O   1 
ATOM 8320 C CB  . ALA A 1 1157 ? 91.491  81.834  101.259 1.00 67.09  ? 1157 ALA A CB  1 
ATOM 8321 N N   . VAL A 1 1158 ? 88.199  81.523  102.967 1.00 60.50  ? 1158 VAL A N   1 
ATOM 8322 C CA  . VAL A 1 1158 ? 87.567  81.745  104.257 1.00 63.38  ? 1158 VAL A CA  1 
ATOM 8323 C C   . VAL A 1 1158 ? 87.096  80.388  104.773 1.00 70.38  ? 1158 VAL A C   1 
ATOM 8324 O O   . VAL A 1 1158 ? 86.421  79.658  104.049 1.00 71.46  ? 1158 VAL A O   1 
ATOM 8325 C CB  . VAL A 1 1158 ? 86.399  82.741  104.143 1.00 71.36  ? 1158 VAL A CB  1 
ATOM 8326 C CG1 . VAL A 1 1158 ? 85.254  82.412  105.100 1.00 73.43  ? 1158 VAL A CG1 1 
ATOM 8327 C CG2 . VAL A 1 1158 ? 86.871  84.179  104.327 1.00 78.64  ? 1158 VAL A CG2 1 
ATOM 8328 N N   . LYS A 1 1159 ? 87.469  80.056  106.015 1.00 70.46  ? 1159 LYS A N   1 
ATOM 8329 C CA  . LYS A 1 1159 ? 87.124  78.775  106.613 1.00 67.64  ? 1159 LYS A CA  1 
ATOM 8330 C C   . LYS A 1 1159 ? 85.959  78.951  107.586 1.00 59.85  ? 1159 LYS A C   1 
ATOM 8331 O O   . LYS A 1 1159 ? 85.895  79.939  108.297 1.00 61.11  ? 1159 LYS A O   1 
ATOM 8332 C CB  . LYS A 1 1159 ? 88.361  78.219  107.314 1.00 70.66  ? 1159 LYS A CB  1 
ATOM 8333 C CG  . LYS A 1 1159 ? 89.579  78.006  106.428 1.00 75.16  ? 1159 LYS A CG  1 
ATOM 8334 C CD  . LYS A 1 1159 ? 90.782  77.491  107.183 1.00 80.88  ? 1159 LYS A CD  1 
ATOM 8335 C CE  . LYS A 1 1159 ? 90.562  76.149  107.847 1.00 87.58  ? 1159 LYS A CE  1 
ATOM 8336 N NZ  . LYS A 1 1159 ? 91.777  75.704  108.565 1.00 92.42  ? 1159 LYS A NZ  1 
ATOM 8337 N N   . SER A 1 1160 ? 85.047  77.983  107.626 1.00 60.95  ? 1160 SER A N   1 
ATOM 8338 C CA  . SER A 1 1160 ? 83.847  78.083  108.442 1.00 66.80  ? 1160 SER A CA  1 
ATOM 8339 C C   . SER A 1 1160 ? 84.190  77.920  109.922 1.00 69.72  ? 1160 SER A C   1 
ATOM 8340 O O   . SER A 1 1160 ? 85.236  77.370  110.266 1.00 69.33  ? 1160 SER A O   1 
ATOM 8341 C CB  . SER A 1 1160 ? 82.832  77.051  107.998 1.00 78.40  ? 1160 SER A CB  1 
ATOM 8342 O OG  . SER A 1 1160 ? 81.690  77.013  108.846 1.00 79.39  ? 1160 SER A OG  1 
ATOM 8343 N N   . GLY A 1 1161 ? 83.293  78.403  110.796 1.00 79.40  ? 1161 GLY A N   1 
ATOM 8344 C CA  . GLY A 1 1161 ? 83.409  78.207  112.238 1.00 82.00  ? 1161 GLY A CA  1 
ATOM 8345 C C   . GLY A 1 1161 ? 84.253  79.281  112.926 1.00 70.02  ? 1161 GLY A C   1 
ATOM 8346 O O   . GLY A 1 1161 ? 84.792  80.173  112.276 1.00 68.92  ? 1161 GLY A O   1 
ATOM 8347 N N   . PHE A 1 1162 ? 84.378  79.180  114.252 1.00 53.85  ? 1162 PHE A N   1 
ATOM 8348 C CA  . PHE A 1 1162 ? 85.049  80.219  115.010 1.00 47.52  ? 1162 PHE A CA  1 
ATOM 8349 C C   . PHE A 1 1162 ? 86.485  80.278  114.537 1.00 38.25  ? 1162 PHE A C   1 
ATOM 8350 O O   . PHE A 1 1162 ? 87.129  79.241  114.492 1.00 41.39  ? 1162 PHE A O   1 
ATOM 8351 C CB  . PHE A 1 1162 ? 85.021  79.932  116.511 1.00 53.32  ? 1162 PHE A CB  1 
ATOM 8352 C CG  . PHE A 1 1162 ? 83.641  79.888  117.111 1.00 58.83  ? 1162 PHE A CG  1 
ATOM 8353 C CD1 . PHE A 1 1162 ? 82.726  78.923  116.719 1.00 61.19  ? 1162 PHE A CD1 1 
ATOM 8354 C CD2 . PHE A 1 1162 ? 83.263  80.804  118.076 1.00 63.44  ? 1162 PHE A CD2 1 
ATOM 8355 C CE1 . PHE A 1 1162 ? 81.458  78.876  117.274 1.00 64.07  ? 1162 PHE A CE1 1 
ATOM 8356 C CE2 . PHE A 1 1162 ? 81.991  80.753  118.630 1.00 70.96  ? 1162 PHE A CE2 1 
ATOM 8357 C CZ  . PHE A 1 1162 ? 81.092  79.792  118.225 1.00 69.08  ? 1162 PHE A CZ  1 
ATOM 8358 N N   . ARG A 1 1163 ? 86.956  81.468  114.167 1.00 36.61  ? 1163 ARG A N   1 
ATOM 8359 C CA  . ARG A 1 1163 ? 88.302  81.607  113.644 1.00 40.61  ? 1163 ARG A CA  1 
ATOM 8360 C C   . ARG A 1 1163 ? 88.824  82.992  113.965 1.00 35.89  ? 1163 ARG A C   1 
ATOM 8361 O O   . ARG A 1 1163 ? 88.065  83.889  114.291 1.00 43.89  ? 1163 ARG A O   1 
ATOM 8362 C CB  . ARG A 1 1163 ? 88.338  81.285  112.148 1.00 54.69  ? 1163 ARG A CB  1 
ATOM 8363 C CG  . ARG A 1 1163 ? 88.028  79.820  111.860 1.00 66.59  ? 1163 ARG A CG  1 
ATOM 8364 C CD  . ARG A 1 1163 ? 88.081  79.362  110.418 1.00 77.85  ? 1163 ARG A CD  1 
ATOM 8365 N NE  . ARG A 1 1163 ? 87.726  77.953  110.330 1.00 79.69  ? 1163 ARG A NE  1 
ATOM 8366 C CZ  . ARG A 1 1163 ? 88.412  76.973  110.911 1.00 81.45  ? 1163 ARG A CZ  1 
ATOM 8367 N NH1 . ARG A 1 1163 ? 89.542  77.246  111.547 1.00 79.67  ? 1163 ARG A NH1 1 
ATOM 8368 N NH2 . ARG A 1 1163 ? 87.980  75.724  110.812 1.00 82.36  ? 1163 ARG A NH2 1 
ATOM 8369 N N   . SER A 1 1164 ? 90.136  83.135  113.940 1.00 34.61  ? 1164 SER A N   1 
ATOM 8370 C CA  . SER A 1 1164 ? 90.767  84.370  114.346 1.00 41.56  ? 1164 SER A CA  1 
ATOM 8371 C C   . SER A 1 1164 ? 91.337  85.036  113.112 1.00 38.71  ? 1164 SER A C   1 
ATOM 8372 O O   . SER A 1 1164 ? 92.090  84.405  112.393 1.00 54.06  ? 1164 SER A O   1 
ATOM 8373 C CB  . SER A 1 1164 ? 91.867  84.083  115.339 1.00 55.04  ? 1164 SER A CB  1 
ATOM 8374 O OG  . SER A 1 1164 ? 92.573  85.259  115.717 1.00 60.82  ? 1164 SER A OG  1 
ATOM 8375 N N   . VAL A 1 1165 ? 91.003  86.294  112.877 1.00 31.20  ? 1165 VAL A N   1 
ATOM 8376 C CA  . VAL A 1 1165 ? 91.540  87.009  111.735 1.00 28.26  ? 1165 VAL A CA  1 
ATOM 8377 C C   . VAL A 1 1165 ? 92.750  87.791  112.199 1.00 21.58  ? 1165 VAL A C   1 
ATOM 8378 O O   . VAL A 1 1165 ? 92.623  88.831  112.820 1.00 24.31  ? 1165 VAL A O   1 
ATOM 8379 C CB  . VAL A 1 1165 ? 90.456  87.916  111.119 1.00 40.10  ? 1165 VAL A CB  1 
ATOM 8380 C CG1 . VAL A 1 1165 ? 89.260  87.084  110.654 1.00 46.18  ? 1165 VAL A CG1 1 
ATOM 8381 C CG2 . VAL A 1 1165 ? 89.981  89.029  112.063 1.00 45.55  ? 1165 VAL A CG2 1 
ATOM 8382 N N   . PRO A 1 1166 ? 93.967  87.357  111.888 1.00 21.79  ? 1166 PRO A N   1 
ATOM 8383 C CA  . PRO A 1 1166 ? 95.145  88.144  112.195 1.00 25.15  ? 1166 PRO A CA  1 
ATOM 8384 C C   . PRO A 1 1166 ? 94.891  89.520  111.608 1.00 28.35  ? 1166 PRO A C   1 
ATOM 8385 O O   . PRO A 1 1166 ? 94.273  89.608  110.550 1.00 31.80  ? 1166 PRO A O   1 
ATOM 8386 C CB  . PRO A 1 1166 ? 96.296  87.478  111.437 1.00 28.85  ? 1166 PRO A CB  1 
ATOM 8387 C CG  . PRO A 1 1166 ? 95.776  86.076  111.182 1.00 31.75  ? 1166 PRO A CG  1 
ATOM 8388 C CD  . PRO A 1 1166 ? 94.274  86.212  111.053 1.00 27.09  ? 1166 PRO A CD  1 
ATOM 8389 N N   . LEU A 1 1167 ? 95.309  90.574  112.324 1.00 27.71  ? 1167 LEU A N   1 
ATOM 8390 C CA  . LEU A 1 1167 ? 95.144  91.941  111.859 1.00 26.21  ? 1167 LEU A CA  1 
ATOM 8391 C C   . LEU A 1 1167 ? 96.493  92.484  111.417 1.00 30.09  ? 1167 LEU A C   1 
ATOM 8392 O O   . LEU A 1 1167 ? 97.519  92.019  111.889 1.00 35.20  ? 1167 LEU A O   1 
ATOM 8393 C CB  . LEU A 1 1167 ? 94.551  92.772  112.989 1.00 25.01  ? 1167 LEU A CB  1 
ATOM 8394 C CG  . LEU A 1 1167 ? 93.148  92.349  113.420 1.00 29.13  ? 1167 LEU A CG  1 
ATOM 8395 C CD1 . LEU A 1 1167 ? 92.497  93.416  114.289 1.00 33.61  ? 1167 LEU A CD1 1 
ATOM 8396 C CD2 . LEU A 1 1167 ? 92.259  92.025  112.236 1.00 30.97  ? 1167 LEU A CD2 1 
ATOM 8397 N N   . LYS A 1 1168 ? 96.477  93.454  110.500 1.00 31.49  ? 1168 LYS A N   1 
ATOM 8398 C CA  . LYS A 1 1168 ? 97.679  93.919  109.833 1.00 34.17  ? 1168 LYS A CA  1 
ATOM 8399 C C   . LYS A 1 1168 ? 97.634  95.431  109.697 1.00 30.73  ? 1168 LYS A C   1 
ATOM 8400 O O   . LYS A 1 1168 ? 96.588  95.963  109.355 1.00 35.77  ? 1168 LYS A O   1 
ATOM 8401 C CB  . LYS A 1 1168 ? 97.743  93.317  108.428 1.00 44.65  ? 1168 LYS A CB  1 
ATOM 8402 C CG  . LYS A 1 1168 ? 97.668  91.800  108.337 1.00 59.48  ? 1168 LYS A CG  1 
ATOM 8403 C CD  . LYS A 1 1168 ? 97.735  91.327  106.885 1.00 73.75  ? 1168 LYS A CD  1 
ATOM 8404 C CE  . LYS A 1 1168 ? 97.573  89.832  106.685 1.00 87.18  ? 1168 LYS A CE  1 
ATOM 8405 N NZ  . LYS A 1 1168 ? 96.268  89.320  107.179 1.00 91.56  ? 1168 LYS A NZ  1 
ATOM 8406 N N   . ASN A 1 1169 ? 98.762  96.112  109.904 1.00 32.11  ? 1169 ASN A N   1 
ATOM 8407 C CA  . ASN A 1 1169 ? 98.832  97.542  109.642 1.00 39.09  ? 1169 ASN A CA  1 
ATOM 8408 C C   . ASN A 1 1169 ? 98.578  97.801  108.163 1.00 43.49  ? 1169 ASN A C   1 
ATOM 8409 O O   . ASN A 1 1169 ? 98.565  96.869  107.375 1.00 45.19  ? 1169 ASN A O   1 
ATOM 8410 C CB  . ASN A 1 1169 ? 100.162 98.171  110.062 1.00 42.67  ? 1169 ASN A CB  1 
ATOM 8411 C CG  . ASN A 1 1169 ? 101.360 97.506  109.429 1.00 48.32  ? 1169 ASN A CG  1 
ATOM 8412 O OD1 . ASN A 1 1169 ? 101.224 96.493  108.746 1.00 56.61  ? 1169 ASN A OD1 1 
ATOM 8413 N ND2 . ASN A 1 1169 ? 102.543 98.044  109.683 1.00 55.06  ? 1169 ASN A ND2 1 
ATOM 8414 N N   . GLY A 1 1170 ? 98.404  99.079  107.798 1.00 53.15  ? 1170 GLY A N   1 
ATOM 8415 C CA  . GLY A 1 1170 ? 97.926  99.471  106.477 1.00 55.02  ? 1170 GLY A CA  1 
ATOM 8416 C C   . GLY A 1 1170 ? 98.806  98.971  105.337 1.00 52.95  ? 1170 GLY A C   1 
ATOM 8417 O O   . GLY A 1 1170 ? 98.356  98.139  104.548 1.00 50.76  ? 1170 GLY A O   1 
ATOM 8418 N N   . TYR A 1 1171 ? 100.044 99.484  105.242 1.00 47.70  ? 1171 TYR A N   1 
ATOM 8419 C CA  . TYR A 1 1171 ? 101.047 98.750  104.498 1.00 46.33  ? 1171 TYR A CA  1 
ATOM 8420 C C   . TYR A 1 1171 ? 100.922 97.352  105.062 1.00 44.73  ? 1171 TYR A C   1 
ATOM 8421 O O   . TYR A 1 1171 ? 101.098 97.225  106.257 1.00 54.99  ? 1171 TYR A O   1 
ATOM 8422 C CB  . TYR A 1 1171 ? 102.445 99.316  104.716 1.00 47.98  ? 1171 TYR A CB  1 
ATOM 8423 C CG  . TYR A 1 1171 ? 102.501 100.811 104.759 1.00 58.16  ? 1171 TYR A CG  1 
ATOM 8424 C CD1 . TYR A 1 1171 ? 101.990 101.587 103.739 1.00 68.21  ? 1171 TYR A CD1 1 
ATOM 8425 C CD2 . TYR A 1 1171 ? 103.047 101.448 105.853 1.00 80.02  ? 1171 TYR A CD2 1 
ATOM 8426 C CE1 . TYR A 1 1171 ? 102.039 102.968 103.804 1.00 83.59  ? 1171 TYR A CE1 1 
ATOM 8427 C CE2 . TYR A 1 1171 ? 103.122 102.828 105.927 1.00 95.51  ? 1171 TYR A CE2 1 
ATOM 8428 C CZ  . TYR A 1 1171 ? 102.608 103.594 104.899 1.00 95.45  ? 1171 TYR A CZ  1 
ATOM 8429 O OH  . TYR A 1 1171 ? 102.667 104.968 104.974 1.00 108.15 ? 1171 TYR A OH  1 
ATOM 8430 N N   . SER A 1 1172 ? 100.461 96.362  104.294 1.00 40.08  ? 1172 SER A N   1 
ATOM 8431 C CA  . SER A 1 1172 ? 99.829  95.220  104.936 1.00 40.54  ? 1172 SER A CA  1 
ATOM 8432 C C   . SER A 1 1172 ? 100.846 94.223  105.508 1.00 51.90  ? 1172 SER A C   1 
ATOM 8433 O O   . SER A 1 1172 ? 100.810 93.048  105.150 1.00 58.47  ? 1172 SER A O   1 
ATOM 8434 C CB  . SER A 1 1172 ? 98.859  94.568  104.011 1.00 37.79  ? 1172 SER A CB  1 
ATOM 8435 O OG  . SER A 1 1172 ? 98.213  93.502  104.687 1.00 40.99  ? 1172 SER A OG  1 
ATOM 8436 N N   . GLU A 1 1173 ? 101.716 94.667  106.436 1.00 62.26  ? 1173 GLU A N   1 
ATOM 8437 C CA  . GLU A 1 1173 ? 102.582 93.770  107.195 1.00 67.99  ? 1173 GLU A CA  1 
ATOM 8438 C C   . GLU A 1 1173 ? 101.757 93.271  108.375 1.00 75.62  ? 1173 GLU A C   1 
ATOM 8439 O O   . GLU A 1 1173 ? 100.549 93.438  108.354 1.00 72.86  ? 1173 GLU A O   1 
ATOM 8440 C CB  . GLU A 1 1173 ? 103.881 94.463  107.606 1.00 74.59  ? 1173 GLU A CB  1 
ATOM 8441 C CG  . GLU A 1 1173 ? 104.778 94.817  106.428 1.00 101.44 ? 1173 GLU A CG  1 
ATOM 8442 C CD  . GLU A 1 1173 ? 104.197 95.798  105.423 1.00 127.23 ? 1173 GLU A CD  1 
ATOM 8443 O OE1 . GLU A 1 1173 ? 103.868 96.931  105.836 1.00 134.15 ? 1173 GLU A OE1 1 
ATOM 8444 O OE2 . GLU A 1 1173 ? 104.057 95.426  104.232 1.00 136.31 ? 1173 GLU A OE2 1 
ATOM 8445 N N   . ASP A 1 1174 ? 102.368 92.645  109.386 1.00 91.71  ? 1174 ASP A N   1 
ATOM 8446 C CA  . ASP A 1 1174 ? 101.566 92.038  110.441 1.00 101.97 ? 1174 ASP A CA  1 
ATOM 8447 C C   . ASP A 1 1174 ? 101.947 92.613  111.804 1.00 100.16 ? 1174 ASP A C   1 
ATOM 8448 O O   . ASP A 1 1174 ? 103.112 92.593  112.186 1.00 103.81 ? 1174 ASP A O   1 
ATOM 8449 C CB  . ASP A 1 1174 ? 101.681 90.511  110.407 1.00 120.73 ? 1174 ASP A CB  1 
ATOM 8450 C CG  . ASP A 1 1174 ? 100.711 89.802  111.338 1.00 142.82 ? 1174 ASP A CG  1 
ATOM 8451 O OD1 . ASP A 1 1174 ? 99.985  90.501  112.072 1.00 147.94 ? 1174 ASP A OD1 1 
ATOM 8452 O OD2 . ASP A 1 1174 ? 100.685 88.553  111.321 1.00 159.42 ? 1174 ASP A OD2 1 
ATOM 8453 N N   . ILE A 1 1175 ? 100.934 93.095  112.546 1.00 98.85  ? 1175 ILE A N   1 
ATOM 8454 C CA  . ILE A 1 1175 ? 101.092 93.556  113.920 1.00 99.54  ? 1175 ILE A CA  1 
ATOM 8455 C C   . ILE A 1 1175 ? 101.170 92.332  114.833 1.00 101.31 ? 1175 ILE A C   1 
ATOM 8456 O O   . ILE A 1 1175 ? 100.629 91.283  114.494 1.00 107.12 ? 1175 ILE A O   1 
ATOM 8457 C CB  . ILE A 1 1175 ? 99.945  94.513  114.321 1.00 108.27 ? 1175 ILE A CB  1 
ATOM 8458 C CG1 . ILE A 1 1175 ? 98.564  93.841  114.291 1.00 111.73 ? 1175 ILE A CG1 1 
ATOM 8459 C CG2 . ILE A 1 1175 ? 99.972  95.775  113.458 1.00 115.68 ? 1175 ILE A CG2 1 
ATOM 8460 C CD1 . ILE A 1 1175 ? 97.409  94.771  114.643 1.00 111.33 ? 1175 ILE A CD1 1 
ATOM 8461 N N   . GLU A 1 1176 ? 101.832 92.466  115.993 1.00 95.25  ? 1176 GLU A N   1 
ATOM 8462 C CA  . GLU A 1 1176 ? 101.985 91.357  116.932 1.00 83.90  ? 1176 GLU A CA  1 
ATOM 8463 C C   . GLU A 1 1176 ? 100.620 90.852  117.393 1.00 64.23  ? 1176 GLU A C   1 
ATOM 8464 O O   . GLU A 1 1176 ? 99.585  91.396  117.022 1.00 63.28  ? 1176 GLU A O   1 
ATOM 8465 C CB  . GLU A 1 1176 ? 102.795 91.766  118.162 1.00 102.94 ? 1176 GLU A CB  1 
ATOM 8466 C CG  . GLU A 1 1176 ? 104.203 92.231  117.845 1.00 130.87 ? 1176 GLU A CG  1 
ATOM 8467 C CD  . GLU A 1 1176 ? 105.086 91.207  117.153 1.00 150.27 ? 1176 GLU A CD  1 
ATOM 8468 O OE1 . GLU A 1 1176 ? 106.220 91.575  116.804 1.00 160.86 ? 1176 GLU A OE1 1 
ATOM 8469 O OE2 . GLU A 1 1176 ? 104.642 90.051  116.972 1.00 149.85 ? 1176 GLU A OE2 1 
ATOM 8470 N N   . LEU A 1 1177 ? 100.641 89.808  118.217 1.00 56.17  ? 1177 LEU A N   1 
ATOM 8471 C CA  . LEU A 1 1177 ? 99.454  89.030  118.515 1.00 59.49  ? 1177 LEU A CA  1 
ATOM 8472 C C   . LEU A 1 1177 ? 98.214  89.914  118.537 1.00 56.34  ? 1177 LEU A C   1 
ATOM 8473 O O   . LEU A 1 1177 ? 97.809  90.304  119.624 1.00 78.18  ? 1177 LEU A O   1 
ATOM 8474 C CB  . LEU A 1 1177 ? 99.623  88.365  119.886 1.00 73.40  ? 1177 LEU A CB  1 
ATOM 8475 C CG  . LEU A 1 1177 ? 100.793 87.389  120.023 1.00 97.42  ? 1177 LEU A CG  1 
ATOM 8476 C CD1 . LEU A 1 1177 ? 102.082 88.117  120.399 1.00 102.57 ? 1177 LEU A CD1 1 
ATOM 8477 C CD2 . LEU A 1 1177 ? 100.463 86.291  121.030 1.00 105.44 ? 1177 LEU A CD2 1 
ATOM 8478 N N   . ALA A 1 1178 ? 97.590  90.199  117.383 1.00 43.20  ? 1178 ALA A N   1 
ATOM 8479 C CA  . ALA A 1 1178 ? 96.285  90.858  117.378 1.00 35.37  ? 1178 ALA A CA  1 
ATOM 8480 C C   . ALA A 1 1178 ? 95.269  89.875  116.845 1.00 26.72  ? 1178 ALA A C   1 
ATOM 8481 O O   . ALA A 1 1178 ? 95.654  88.781  116.482 1.00 29.58  ? 1178 ALA A O   1 
ATOM 8482 C CB  . ALA A 1 1178 ? 96.322  92.110  116.551 1.00 38.63  ? 1178 ALA A CB  1 
ATOM 8483 N N   . SER A 1 1179 ? 93.999  90.238  116.808 1.00 26.29  ? 1179 SER A N   1 
ATOM 8484 C CA  . SER A 1 1179 ? 93.011  89.321  116.261 1.00 33.86  ? 1179 SER A CA  1 
ATOM 8485 C C   . SER A 1 1179 ? 91.609  89.840  116.501 1.00 33.45  ? 1179 SER A C   1 
ATOM 8486 O O   . SER A 1 1179 ? 91.410  90.589  117.443 1.00 42.25  ? 1179 SER A O   1 
ATOM 8487 C CB  . SER A 1 1179 ? 93.113  87.956  116.890 1.00 43.18  ? 1179 SER A CB  1 
ATOM 8488 O OG  . SER A 1 1179 ? 92.978  88.020  118.312 1.00 47.30  ? 1179 SER A OG  1 
ATOM 8489 N N   . LEU A 1 1180 ? 90.658  89.346  115.717 1.00 32.01  ? 1180 LEU A N   1 
ATOM 8490 C CA  . LEU A 1 1180 ? 89.247  89.546  115.967 1.00 38.35  ? 1180 LEU A CA  1 
ATOM 8491 C C   . LEU A 1 1180 ? 88.569  88.196  115.824 1.00 40.60  ? 1180 LEU A C   1 
ATOM 8492 O O   . LEU A 1 1180 ? 88.265  87.802  114.700 1.00 45.06  ? 1180 LEU A O   1 
ATOM 8493 C CB  . LEU A 1 1180 ? 88.627  90.481  114.917 1.00 42.46  ? 1180 LEU A CB  1 
ATOM 8494 C CG  . LEU A 1 1180 ? 89.270  91.847  114.718 1.00 47.69  ? 1180 LEU A CG  1 
ATOM 8495 C CD1 . LEU A 1 1180 ? 88.439  92.644  113.729 1.00 56.31  ? 1180 LEU A CD1 1 
ATOM 8496 C CD2 . LEU A 1 1180 ? 89.419  92.603  116.038 1.00 46.41  ? 1180 LEU A CD2 1 
ATOM 8497 N N   . LEU A 1 1181 ? 88.294  87.498  116.924 1.00 41.38  ? 1181 LEU A N   1 
ATOM 8498 C CA  . LEU A 1 1181 ? 87.605  86.232  116.740 1.00 43.14  ? 1181 LEU A CA  1 
ATOM 8499 C C   . LEU A 1 1181 ? 86.316  86.534  115.992 1.00 36.78  ? 1181 LEU A C   1 
ATOM 8500 O O   . LEU A 1 1181 ? 85.652  87.498  116.328 1.00 41.83  ? 1181 LEU A O   1 
ATOM 8501 C CB  . LEU A 1 1181 ? 87.315  85.542  118.073 1.00 52.72  ? 1181 LEU A CB  1 
ATOM 8502 C CG  . LEU A 1 1181 ? 86.645  84.179  117.935 1.00 72.26  ? 1181 LEU A CG  1 
ATOM 8503 C CD1 . LEU A 1 1181 ? 87.674  83.115  117.533 1.00 76.88  ? 1181 LEU A CD1 1 
ATOM 8504 C CD2 . LEU A 1 1181 ? 85.892  83.807  119.212 1.00 84.34  ? 1181 LEU A CD2 1 
ATOM 8505 N N   . VAL A 1 1182 ? 85.992  85.742  114.972 1.00 36.74  ? 1182 VAL A N   1 
ATOM 8506 C CA  . VAL A 1 1182 ? 84.780  85.917  114.192 1.00 43.81  ? 1182 VAL A CA  1 
ATOM 8507 C C   . VAL A 1 1182 ? 84.137  84.552  114.029 1.00 44.57  ? 1182 VAL A C   1 
ATOM 8508 O O   . VAL A 1 1182 ? 84.806  83.539  114.218 1.00 53.74  ? 1182 VAL A O   1 
ATOM 8509 C CB  . VAL A 1 1182 ? 85.093  86.544  112.821 1.00 61.50  ? 1182 VAL A CB  1 
ATOM 8510 C CG1 . VAL A 1 1182 ? 85.646  87.962  112.945 1.00 70.97  ? 1182 VAL A CG1 1 
ATOM 8511 C CG2 . VAL A 1 1182 ? 86.052  85.685  112.004 1.00 72.09  ? 1182 VAL A CG2 1 
ATOM 8512 N N   . PHE A 1 1183 ? 82.861  84.522  113.649 1.00 49.87  ? 1183 PHE A N   1 
ATOM 8513 C CA  . PHE A 1 1183 ? 82.162  83.257  113.514 1.00 64.02  ? 1183 PHE A CA  1 
ATOM 8514 C C   . PHE A 1 1183 ? 81.622  83.110  112.097 1.00 75.00  ? 1183 PHE A C   1 
ATOM 8515 O O   . PHE A 1 1183 ? 80.433  82.854  111.911 1.00 79.82  ? 1183 PHE A O   1 
ATOM 8516 C CB  . PHE A 1 1183 ? 81.058  83.152  114.568 1.00 74.47  ? 1183 PHE A CB  1 
ATOM 8517 C CG  . PHE A 1 1183 ? 80.159  81.954  114.409 1.00 85.13  ? 1183 PHE A CG  1 
ATOM 8518 C CD1 . PHE A 1 1183 ? 80.675  80.672  114.440 1.00 88.94  ? 1183 PHE A CD1 1 
ATOM 8519 C CD2 . PHE A 1 1183 ? 78.796  82.113  114.201 1.00 99.22  ? 1183 PHE A CD2 1 
ATOM 8520 C CE1 . PHE A 1 1183 ? 79.843  79.575  114.277 1.00 101.79 ? 1183 PHE A CE1 1 
ATOM 8521 C CE2 . PHE A 1 1183 ? 77.967  81.014  114.043 1.00 103.46 ? 1183 PHE A CE2 1 
ATOM 8522 C CZ  . PHE A 1 1183 ? 78.492  79.746  114.084 1.00 105.17 ? 1183 PHE A CZ  1 
ATOM 8523 N N   . CYS A 1 1184 ? 82.509  83.261  111.103 1.00 85.35  ? 1184 CYS A N   1 
ATOM 8524 C CA  . CYS A 1 1184 ? 82.131  83.108  109.703 1.00 87.79  ? 1184 CYS A CA  1 
ATOM 8525 C C   . CYS A 1 1184 ? 81.466  81.750  109.481 1.00 86.68  ? 1184 CYS A C   1 
ATOM 8526 O O   . CYS A 1 1184 ? 81.992  80.728  109.911 1.00 92.94  ? 1184 CYS A O   1 
ATOM 8527 C CB  . CYS A 1 1184 ? 83.344  83.210  108.788 1.00 86.90  ? 1184 CYS A CB  1 
ATOM 8528 S SG  . CYS A 1 1184 ? 84.379  84.658  109.118 1.00 99.70  ? 1184 CYS A SG  1 
ATOM 8529 N N   . GLU A 1 1185 ? 80.288  81.765  108.858 1.00 85.77  ? 1185 GLU A N   1 
ATOM 8530 C CA  . GLU A 1 1185 ? 79.701  80.571  108.279 1.00 99.77  ? 1185 GLU A CA  1 
ATOM 8531 C C   . GLU A 1 1185 ? 79.462  80.860  106.804 1.00 105.02 ? 1185 GLU A C   1 
ATOM 8532 O O   . GLU A 1 1185 ? 78.729  81.786  106.487 1.00 113.38 ? 1185 GLU A O   1 
ATOM 8533 C CB  . GLU A 1 1185 ? 78.384  80.219  108.973 1.00 114.98 ? 1185 GLU A CB  1 
ATOM 8534 C CG  . GLU A 1 1185 ? 77.468  79.337  108.134 1.00 132.71 ? 1185 GLU A CG  1 
ATOM 8535 C CD  . GLU A 1 1185 ? 75.986  79.488  108.437 1.00 147.51 ? 1185 GLU A CD  1 
ATOM 8536 O OE1 . GLU A 1 1185 ? 75.354  78.480  108.814 1.00 158.11 ? 1185 GLU A OE1 1 
ATOM 8537 O OE2 . GLU A 1 1185 ? 75.461  80.614  108.290 1.00 146.44 ? 1185 GLU A OE2 1 
ATOM 8538 N N   . MET A 1 1186 ? 80.056  80.065  105.909 1.00 100.60 ? 1186 MET A N   1 
ATOM 8539 C CA  . MET A 1 1186 ? 79.983  80.350  104.484 1.00 94.99  ? 1186 MET A CA  1 
ATOM 8540 C C   . MET A 1 1186 ? 79.068  79.350  103.787 1.00 86.30  ? 1186 MET A C   1 
ATOM 8541 O O   . MET A 1 1186 ? 79.482  78.697  102.832 1.00 84.46  ? 1186 MET A O   1 
ATOM 8542 C CB  . MET A 1 1186 ? 81.368  80.280  103.838 1.00 108.87 ? 1186 MET A CB  1 
ATOM 8543 C CG  . MET A 1 1186 ? 81.994  81.633  103.590 1.00 126.31 ? 1186 MET A CG  1 
ATOM 8544 S SD  . MET A 1 1186 ? 83.088  81.640  102.135 1.00 164.08 ? 1186 MET A SD  1 
ATOM 8545 C CE  . MET A 1 1186 ? 83.711  79.957  102.132 1.00 177.44 ? 1186 MET A CE  1 
ATOM 8546 N N   . ARG A 1 1187 ? 77.819  79.254  104.251 1.00 88.09  ? 1187 ARG A N   1 
ATOM 8547 C CA  . ARG A 1 1187 ? 76.857  78.352  103.642 1.00 103.08 ? 1187 ARG A CA  1 
ATOM 8548 C C   . ARG A 1 1187 ? 76.688  78.727  102.172 1.00 111.66 ? 1187 ARG A C   1 
ATOM 8549 O O   . ARG A 1 1187 ? 76.679  79.906  101.848 1.00 118.10 ? 1187 ARG A O   1 
ATOM 8550 C CB  . ARG A 1 1187 ? 75.513  78.441  104.367 1.00 116.71 ? 1187 ARG A CB  1 
ATOM 8551 C CG  . ARG A 1 1187 ? 74.505  77.379  103.949 1.00 131.87 ? 1187 ARG A CG  1 
ATOM 8552 C CD  . ARG A 1 1187 ? 73.218  77.479  104.749 1.00 148.18 ? 1187 ARG A CD  1 
ATOM 8553 N NE  . ARG A 1 1187 ? 72.336  78.551  104.296 1.00 160.81 ? 1187 ARG A NE  1 
ATOM 8554 C CZ  . ARG A 1 1187 ? 72.092  79.680  104.957 1.00 174.32 ? 1187 ARG A CZ  1 
ATOM 8555 N NH1 . ARG A 1 1187 ? 72.790  79.993  106.036 1.00 180.00 ? 1187 ARG A NH1 1 
ATOM 8556 N NH2 . ARG A 1 1187 ? 71.164  80.513  104.516 1.00 175.84 ? 1187 ARG A NH2 1 
ATOM 8557 N N   . PRO A 1 1188 ? 76.583  77.757  101.233 1.00 125.63 ? 1188 PRO A N   1 
ATOM 8558 C CA  . PRO A 1 1188 ? 76.193  78.046  99.855  1.00 124.82 ? 1188 PRO A CA  1 
ATOM 8559 C C   . PRO A 1 1188 ? 74.681  77.926  99.717  1.00 124.35 ? 1188 PRO A C   1 
ATOM 8560 O O   . PRO A 1 1188 ? 74.055  77.177  100.461 1.00 124.33 ? 1188 PRO A O   1 
ATOM 8561 C CB  . PRO A 1 1188 ? 76.903  76.934  99.081  1.00 130.79 ? 1188 PRO A CB  1 
ATOM 8562 C CG  . PRO A 1 1188 ? 76.787  75.746  100.017 1.00 144.04 ? 1188 PRO A CG  1 
ATOM 8563 C CD  . PRO A 1 1188 ? 76.856  76.324  101.422 1.00 142.31 ? 1188 PRO A CD  1 
ATOM 8564 N N   . VAL A 1 1189 ? 74.103  78.672  98.773  1.00 127.79 ? 1189 VAL A N   1 
ATOM 8565 C CA  . VAL A 1 1189 ? 72.663  78.672  98.592  1.00 137.07 ? 1189 VAL A CA  1 
ATOM 8566 C C   . VAL A 1 1189 ? 72.343  78.074  97.229  1.00 149.97 ? 1189 VAL A C   1 
ATOM 8567 O O   . VAL A 1 1189 ? 72.906  78.494  96.222  1.00 151.73 ? 1189 VAL A O   1 
ATOM 8568 C CB  . VAL A 1 1189 ? 72.076  80.087  98.734  1.00 143.51 ? 1189 VAL A CB  1 
ATOM 8569 C CG1 . VAL A 1 1189 ? 70.669  80.172  98.162  1.00 148.53 ? 1189 VAL A CG1 1 
ATOM 8570 C CG2 . VAL A 1 1189 ? 72.100  80.558  100.179 1.00 148.29 ? 1189 VAL A CG2 1 
ATOM 8571 N N   . LEU A 1 1190 ? 71.417  77.107  97.226  1.00 169.43 ? 1190 LEU A N   1 
ATOM 8572 C CA  . LEU A 1 1190 ? 70.967  76.449  96.010  1.00 190.90 ? 1190 LEU A CA  1 
ATOM 8573 C C   . LEU A 1 1190 ? 69.463  76.169  96.118  1.00 189.64 ? 1190 LEU A C   1 
ATOM 8574 O O   . LEU A 1 1190 ? 68.740  76.558  95.177  1.00 182.89 ? 1190 LEU A O   1 
ATOM 8575 C CB  . LEU A 1 1190 ? 71.761  75.152  95.817  1.00 202.66 ? 1190 LEU A CB  1 
ATOM 8576 C CG  . LEU A 1 1190 ? 73.208  75.308  95.343  1.00 205.55 ? 1190 LEU A CG  1 
ATOM 8577 C CD1 . LEU A 1 1190 ? 73.896  73.955  95.247  1.00 204.57 ? 1190 LEU A CD1 1 
ATOM 8578 C CD2 . LEU A 1 1190 ? 73.274  76.030  94.002  1.00 203.89 ? 1190 LEU A CD2 1 
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