data_8QIZ
# 
_entry.id   8QIZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8QIZ         pdb_00008qiz 10.2210/pdb8qiz/pdb 
WWPDB D_1292133276 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8QIZ 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              pdb@casperwilkens.dk 
_pdbx_contact_author.name_first         Casper 
_pdbx_contact_author.name_last          Wilkens 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7692-067X 
# 
_audit_author.name               'Wilkens, C.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0001-7692-067X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystal structure of Paradendryphiella salina PL7C alginate lyase mutant H124 soaked with with penta-mannuronic acid' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Wilkens, C.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0001-7692-067X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'Alginate lyase' 25520.199 1   ? H124N ? ? 
2 branched man 
;beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
;
1074.758  1   ? ?     ? ? 
3 branched man 
;beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
;
722.510   1   ? ?     ? ? 
4 water    nat water 18.015    337 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;EFLTAVSSIDTFLPVLNEAKLQWPTSALAASSEELLGGYVGSQFYLQDGKYMQFQIAGSSNRCELRQMIPDGGSEIGWAV
DDGTTHTATSSIVVPEQVDGVEEVTIMQINSGEAPQLRISWIRSKSLDGVAYEDFIMSTVRIGTGDSSDNFVKTHLADRT
AGAMSFQIDVKDSKLTITVNGNVVVNGQDLSFWDGTDSCYFKAGAYNNNPTSESATARIKFAALAWVDHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;EFLTAVSSIDTFLPVLNEAKLQWPTSALAASSEELLGGYVGSQFYLQDGKYMQFQIAGSSNRCELRQMIPDGGSEIGWAV
DDGTTHTATSSIVVPEQVDGVEEVTIMQINSGEAPQLRISWIRSKSLDGVAYEDFIMSTVRIGTGDSSDNFVKTHLADRT
AGAMSFQIDVKDSKLTITVNGNVVVNGQDLSFWDGTDSCYFKAGAYNNNPTSESATARIKFAALAWVDHHHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   PHE n 
1 3   LEU n 
1 4   THR n 
1 5   ALA n 
1 6   VAL n 
1 7   SER n 
1 8   SER n 
1 9   ILE n 
1 10  ASP n 
1 11  THR n 
1 12  PHE n 
1 13  LEU n 
1 14  PRO n 
1 15  VAL n 
1 16  LEU n 
1 17  ASN n 
1 18  GLU n 
1 19  ALA n 
1 20  LYS n 
1 21  LEU n 
1 22  GLN n 
1 23  TRP n 
1 24  PRO n 
1 25  THR n 
1 26  SER n 
1 27  ALA n 
1 28  LEU n 
1 29  ALA n 
1 30  ALA n 
1 31  SER n 
1 32  SER n 
1 33  GLU n 
1 34  GLU n 
1 35  LEU n 
1 36  LEU n 
1 37  GLY n 
1 38  GLY n 
1 39  TYR n 
1 40  VAL n 
1 41  GLY n 
1 42  SER n 
1 43  GLN n 
1 44  PHE n 
1 45  TYR n 
1 46  LEU n 
1 47  GLN n 
1 48  ASP n 
1 49  GLY n 
1 50  LYS n 
1 51  TYR n 
1 52  MET n 
1 53  GLN n 
1 54  PHE n 
1 55  GLN n 
1 56  ILE n 
1 57  ALA n 
1 58  GLY n 
1 59  SER n 
1 60  SER n 
1 61  ASN n 
1 62  ARG n 
1 63  CYS n 
1 64  GLU n 
1 65  LEU n 
1 66  ARG n 
1 67  GLN n 
1 68  MET n 
1 69  ILE n 
1 70  PRO n 
1 71  ASP n 
1 72  GLY n 
1 73  GLY n 
1 74  SER n 
1 75  GLU n 
1 76  ILE n 
1 77  GLY n 
1 78  TRP n 
1 79  ALA n 
1 80  VAL n 
1 81  ASP n 
1 82  ASP n 
1 83  GLY n 
1 84  THR n 
1 85  THR n 
1 86  HIS n 
1 87  THR n 
1 88  ALA n 
1 89  THR n 
1 90  SER n 
1 91  SER n 
1 92  ILE n 
1 93  VAL n 
1 94  VAL n 
1 95  PRO n 
1 96  GLU n 
1 97  GLN n 
1 98  VAL n 
1 99  ASP n 
1 100 GLY n 
1 101 VAL n 
1 102 GLU n 
1 103 GLU n 
1 104 VAL n 
1 105 THR n 
1 106 ILE n 
1 107 MET n 
1 108 GLN n 
1 109 ILE n 
1 110 ASN n 
1 111 SER n 
1 112 GLY n 
1 113 GLU n 
1 114 ALA n 
1 115 PRO n 
1 116 GLN n 
1 117 LEU n 
1 118 ARG n 
1 119 ILE n 
1 120 SER n 
1 121 TRP n 
1 122 ILE n 
1 123 ARG n 
1 124 SER n 
1 125 LYS n 
1 126 SER n 
1 127 LEU n 
1 128 ASP n 
1 129 GLY n 
1 130 VAL n 
1 131 ALA n 
1 132 TYR n 
1 133 GLU n 
1 134 ASP n 
1 135 PHE n 
1 136 ILE n 
1 137 MET n 
1 138 SER n 
1 139 THR n 
1 140 VAL n 
1 141 ARG n 
1 142 ILE n 
1 143 GLY n 
1 144 THR n 
1 145 GLY n 
1 146 ASP n 
1 147 SER n 
1 148 SER n 
1 149 ASP n 
1 150 ASN n 
1 151 PHE n 
1 152 VAL n 
1 153 LYS n 
1 154 THR n 
1 155 HIS n 
1 156 LEU n 
1 157 ALA n 
1 158 ASP n 
1 159 ARG n 
1 160 THR n 
1 161 ALA n 
1 162 GLY n 
1 163 ALA n 
1 164 MET n 
1 165 SER n 
1 166 PHE n 
1 167 GLN n 
1 168 ILE n 
1 169 ASP n 
1 170 VAL n 
1 171 LYS n 
1 172 ASP n 
1 173 SER n 
1 174 LYS n 
1 175 LEU n 
1 176 THR n 
1 177 ILE n 
1 178 THR n 
1 179 VAL n 
1 180 ASN n 
1 181 GLY n 
1 182 ASN n 
1 183 VAL n 
1 184 VAL n 
1 185 VAL n 
1 186 ASN n 
1 187 GLY n 
1 188 GLN n 
1 189 ASP n 
1 190 LEU n 
1 191 SER n 
1 192 PHE n 
1 193 TRP n 
1 194 ASP n 
1 195 GLY n 
1 196 THR n 
1 197 ASP n 
1 198 SER n 
1 199 CYS n 
1 200 TYR n 
1 201 PHE n 
1 202 LYS n 
1 203 ALA n 
1 204 GLY n 
1 205 ALA n 
1 206 TYR n 
1 207 ASN n 
1 208 ASN n 
1 209 ASN n 
1 210 PRO n 
1 211 THR n 
1 212 SER n 
1 213 GLU n 
1 214 SER n 
1 215 ALA n 
1 216 THR n 
1 217 ALA n 
1 218 ARG n 
1 219 ILE n 
1 220 LYS n 
1 221 PHE n 
1 222 ALA n 
1 223 ALA n 
1 224 LEU n 
1 225 ALA n 
1 226 TRP n 
1 227 VAL n 
1 228 ASP n 
1 229 HIS n 
1 230 HIS n 
1 231 HIS n 
1 232 HIS n 
1 233 HIS n 
1 234 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   234 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PsAlg7C 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Paradendryphiella salina' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     179392 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Komagataella pastoris' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4922 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DManpAb1-4DManpAb1-4DManpAb1-4DManpAb1-4LGulpAa1-4DManpAb1-ROH                                                        
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/2,6,5/[a1122A-1b_1-5][a1121A-1a_1-5]/1-2-1-1-1-1/a4-b1_b4-c1_c4-d1_d4-e1_e4-f1'                            WURCS 
PDB2Glycan 1.1.0 
3 2 '[][b-D-ManpA]{[(4+1)][a-L-GulpA]{[(4+1)][b-D-ManpA]{[(4+1)][b-D-ManpA]{[(4+1)][b-D-ManpA]{[(4+1)][b-D-ManpA]{}}}}}}' LINUCS 
PDB-CARE   ?     
4 3 DManpAb1-4DManpAb1-4DManpAb1-4DManpAb1-ROH                                                                            
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/1,4,3/[a1122A-1b_1-5]/1-1-1-1/a4-b1_b4-c1_c4-d1'                                                           WURCS 
PDB2Glycan 1.1.0 
6 3 '[][b-D-ManpA]{[(4+1)][b-D-ManpA]{[(4+1)][b-D-ManpA]{[(4+1)][b-D-ManpA]{}}}}'                                         LINUCS 
PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 LGU C1 O1 1 BEM O4 HO4 sing ? 
2 2 3 BEM C1 O1 2 LGU O4 HO4 sing ? 
3 2 4 BEM C1 O1 3 BEM O4 HO4 sing ? 
4 2 5 BEM C1 O1 4 BEM O4 HO4 sing ? 
5 2 6 BEM C1 O1 5 BEM O4 HO4 sing ? 
6 3 2 BEM C1 O1 1 BEM O4 HO4 sing ? 
7 3 3 BEM C1 O1 2 BEM O4 HO4 sing ? 
8 3 4 BEM C1 O1 3 BEM O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                        ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                       ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                     ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                ? 'C4 H7 N O4'     133.103 
BEM 'D-saccharide, beta linking'  . 'beta-D-mannopyranuronic acid' 
'beta-D-mannuronic acid; D-mannuronic acid; mannuronic acid; (2S,3S,4S,5S,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid' 
'C6 H10 O7'      194.139 
CYS 'L-peptide linking'           y CYSTEINE                       ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE                      ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                        ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                      ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                          ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                     ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                        ? 'C6 H13 N O2'    131.173 
LGU 'L-saccharide, alpha linking' . 'alpha-L-gulopyranuronic acid' 
'alpha-L-guluronic acid; L-guluronic acid; guluronic acid; ALPHA-L-GULURONATE'                                             
'C6 H10 O7'      194.139 
LYS 'L-peptide linking'           y LYSINE                         ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                     ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'           y PHENYLALANINE                  ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                        ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                         ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                      ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                     ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                       ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                         ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BEM 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpAb                     
BEM 'COMMON NAME'                         GMML     1.0 'b-D-mannopyranuronic acid' 
BEM 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-ManpA                   
BEM 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 ManA                        
LGU 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LGulpAa                     
LGU 'COMMON NAME'                         GMML     1.0 'a-L-gulopyranuronic acid'  
LGU 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-GulpA                   
LGU 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GulA                        
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   15  15  GLU GLU A . n 
A 1 2   PHE 2   16  16  PHE PHE A . n 
A 1 3   LEU 3   17  17  LEU LEU A . n 
A 1 4   THR 4   18  18  THR THR A . n 
A 1 5   ALA 5   19  19  ALA ALA A . n 
A 1 6   VAL 6   20  20  VAL VAL A . n 
A 1 7   SER 7   21  21  SER SER A . n 
A 1 8   SER 8   22  22  SER SER A . n 
A 1 9   ILE 9   23  23  ILE ILE A . n 
A 1 10  ASP 10  24  24  ASP ASP A . n 
A 1 11  THR 11  25  25  THR THR A . n 
A 1 12  PHE 12  26  26  PHE PHE A . n 
A 1 13  LEU 13  27  27  LEU LEU A . n 
A 1 14  PRO 14  28  28  PRO PRO A . n 
A 1 15  VAL 15  29  29  VAL VAL A . n 
A 1 16  LEU 16  30  30  LEU LEU A . n 
A 1 17  ASN 17  31  31  ASN ASN A . n 
A 1 18  GLU 18  32  32  GLU GLU A . n 
A 1 19  ALA 19  33  33  ALA ALA A . n 
A 1 20  LYS 20  34  34  LYS LYS A . n 
A 1 21  LEU 21  35  35  LEU LEU A . n 
A 1 22  GLN 22  36  36  GLN GLN A . n 
A 1 23  TRP 23  37  37  TRP TRP A . n 
A 1 24  PRO 24  38  38  PRO PRO A . n 
A 1 25  THR 25  39  39  THR THR A . n 
A 1 26  SER 26  40  40  SER SER A . n 
A 1 27  ALA 27  41  41  ALA ALA A . n 
A 1 28  LEU 28  42  42  LEU LEU A . n 
A 1 29  ALA 29  43  43  ALA ALA A . n 
A 1 30  ALA 30  44  44  ALA ALA A . n 
A 1 31  SER 31  45  45  SER SER A . n 
A 1 32  SER 32  46  46  SER SER A . n 
A 1 33  GLU 33  47  47  GLU GLU A . n 
A 1 34  GLU 34  48  48  GLU GLU A . n 
A 1 35  LEU 35  49  49  LEU LEU A . n 
A 1 36  LEU 36  50  50  LEU LEU A . n 
A 1 37  GLY 37  51  51  GLY GLY A . n 
A 1 38  GLY 38  52  52  GLY GLY A . n 
A 1 39  TYR 39  53  53  TYR TYR A . n 
A 1 40  VAL 40  54  54  VAL VAL A . n 
A 1 41  GLY 41  55  55  GLY GLY A . n 
A 1 42  SER 42  56  56  SER SER A . n 
A 1 43  GLN 43  57  57  GLN GLN A . n 
A 1 44  PHE 44  58  58  PHE PHE A . n 
A 1 45  TYR 45  59  59  TYR TYR A . n 
A 1 46  LEU 46  60  60  LEU LEU A . n 
A 1 47  GLN 47  61  61  GLN GLN A . n 
A 1 48  ASP 48  62  62  ASP ASP A . n 
A 1 49  GLY 49  63  63  GLY GLY A . n 
A 1 50  LYS 50  64  64  LYS LYS A . n 
A 1 51  TYR 51  65  65  TYR TYR A . n 
A 1 52  MET 52  66  66  MET MET A . n 
A 1 53  GLN 53  67  67  GLN GLN A . n 
A 1 54  PHE 54  68  68  PHE PHE A . n 
A 1 55  GLN 55  69  69  GLN GLN A . n 
A 1 56  ILE 56  70  70  ILE ILE A . n 
A 1 57  ALA 57  71  71  ALA ALA A . n 
A 1 58  GLY 58  72  72  GLY GLY A . n 
A 1 59  SER 59  73  73  SER SER A . n 
A 1 60  SER 60  74  74  SER SER A . n 
A 1 61  ASN 61  75  75  ASN ASN A . n 
A 1 62  ARG 62  76  76  ARG ARG A . n 
A 1 63  CYS 63  77  77  CYS CYS A . n 
A 1 64  GLU 64  78  78  GLU GLU A . n 
A 1 65  LEU 65  79  79  LEU LEU A . n 
A 1 66  ARG 66  80  80  ARG ARG A . n 
A 1 67  GLN 67  81  81  GLN GLN A . n 
A 1 68  MET 68  82  82  MET MET A . n 
A 1 69  ILE 69  83  83  ILE ILE A . n 
A 1 70  PRO 70  84  84  PRO PRO A . n 
A 1 71  ASP 71  85  85  ASP ASP A . n 
A 1 72  GLY 72  86  86  GLY GLY A . n 
A 1 73  GLY 73  87  87  GLY GLY A . n 
A 1 74  SER 74  88  88  SER SER A . n 
A 1 75  GLU 75  89  89  GLU GLU A . n 
A 1 76  ILE 76  90  90  ILE ILE A . n 
A 1 77  GLY 77  91  91  GLY GLY A . n 
A 1 78  TRP 78  92  92  TRP TRP A . n 
A 1 79  ALA 79  93  93  ALA ALA A . n 
A 1 80  VAL 80  94  94  VAL VAL A . n 
A 1 81  ASP 81  95  95  ASP ASP A . n 
A 1 82  ASP 82  96  96  ASP ASP A . n 
A 1 83  GLY 83  97  97  GLY GLY A . n 
A 1 84  THR 84  98  98  THR THR A . n 
A 1 85  THR 85  99  99  THR THR A . n 
A 1 86  HIS 86  100 100 HIS HIS A . n 
A 1 87  THR 87  101 101 THR THR A . n 
A 1 88  ALA 88  102 102 ALA ALA A . n 
A 1 89  THR 89  103 103 THR THR A . n 
A 1 90  SER 90  104 104 SER SER A . n 
A 1 91  SER 91  105 105 SER SER A . n 
A 1 92  ILE 92  106 106 ILE ILE A . n 
A 1 93  VAL 93  107 107 VAL VAL A . n 
A 1 94  VAL 94  108 108 VAL VAL A . n 
A 1 95  PRO 95  109 109 PRO PRO A . n 
A 1 96  GLU 96  110 110 GLU GLU A . n 
A 1 97  GLN 97  111 111 GLN GLN A . n 
A 1 98  VAL 98  112 112 VAL VAL A . n 
A 1 99  ASP 99  113 113 ASP ASP A . n 
A 1 100 GLY 100 114 114 GLY GLY A . n 
A 1 101 VAL 101 115 115 VAL VAL A . n 
A 1 102 GLU 102 116 116 GLU GLU A . n 
A 1 103 GLU 103 117 117 GLU GLU A . n 
A 1 104 VAL 104 118 118 VAL VAL A . n 
A 1 105 THR 105 119 119 THR THR A . n 
A 1 106 ILE 106 120 120 ILE ILE A . n 
A 1 107 MET 107 121 121 MET MET A . n 
A 1 108 GLN 108 122 122 GLN GLN A . n 
A 1 109 ILE 109 123 123 ILE ILE A . n 
A 1 110 ASN 110 124 124 ASN ASN A . n 
A 1 111 SER 111 125 125 SER SER A . n 
A 1 112 GLY 112 126 126 GLY GLY A . n 
A 1 113 GLU 113 127 127 GLU GLU A . n 
A 1 114 ALA 114 128 128 ALA ALA A . n 
A 1 115 PRO 115 129 129 PRO PRO A . n 
A 1 116 GLN 116 130 130 GLN GLN A . n 
A 1 117 LEU 117 131 131 LEU LEU A . n 
A 1 118 ARG 118 132 132 ARG ARG A . n 
A 1 119 ILE 119 133 133 ILE ILE A . n 
A 1 120 SER 120 134 134 SER SER A . n 
A 1 121 TRP 121 135 135 TRP TRP A . n 
A 1 122 ILE 122 136 136 ILE ILE A . n 
A 1 123 ARG 123 137 137 ARG ARG A . n 
A 1 124 SER 124 138 138 SER SER A . n 
A 1 125 LYS 125 139 139 LYS LYS A . n 
A 1 126 SER 126 140 140 SER SER A . n 
A 1 127 LEU 127 141 141 LEU LEU A . n 
A 1 128 ASP 128 142 142 ASP ASP A . n 
A 1 129 GLY 129 143 143 GLY GLY A . n 
A 1 130 VAL 130 144 144 VAL VAL A . n 
A 1 131 ALA 131 145 145 ALA ALA A . n 
A 1 132 TYR 132 146 146 TYR TYR A . n 
A 1 133 GLU 133 147 147 GLU GLU A . n 
A 1 134 ASP 134 148 148 ASP ASP A . n 
A 1 135 PHE 135 149 149 PHE PHE A . n 
A 1 136 ILE 136 150 150 ILE ILE A . n 
A 1 137 MET 137 151 151 MET MET A . n 
A 1 138 SER 138 152 152 SER SER A . n 
A 1 139 THR 139 153 153 THR THR A . n 
A 1 140 VAL 140 154 154 VAL VAL A . n 
A 1 141 ARG 141 155 155 ARG ARG A . n 
A 1 142 ILE 142 156 156 ILE ILE A . n 
A 1 143 GLY 143 157 157 GLY GLY A . n 
A 1 144 THR 144 158 158 THR THR A . n 
A 1 145 GLY 145 159 159 GLY GLY A . n 
A 1 146 ASP 146 160 160 ASP ASP A . n 
A 1 147 SER 147 161 161 SER SER A . n 
A 1 148 SER 148 162 162 SER SER A . n 
A 1 149 ASP 149 163 163 ASP ASP A . n 
A 1 150 ASN 150 164 164 ASN ASN A . n 
A 1 151 PHE 151 165 165 PHE PHE A . n 
A 1 152 VAL 152 166 166 VAL VAL A . n 
A 1 153 LYS 153 167 167 LYS LYS A . n 
A 1 154 THR 154 168 168 THR THR A . n 
A 1 155 HIS 155 169 169 HIS HIS A . n 
A 1 156 LEU 156 170 170 LEU LEU A . n 
A 1 157 ALA 157 171 171 ALA ALA A . n 
A 1 158 ASP 158 172 172 ASP ASP A . n 
A 1 159 ARG 159 173 173 ARG ARG A . n 
A 1 160 THR 160 174 174 THR THR A . n 
A 1 161 ALA 161 175 175 ALA ALA A . n 
A 1 162 GLY 162 176 176 GLY GLY A . n 
A 1 163 ALA 163 177 177 ALA ALA A . n 
A 1 164 MET 164 178 178 MET MET A . n 
A 1 165 SER 165 179 179 SER SER A . n 
A 1 166 PHE 166 180 180 PHE PHE A . n 
A 1 167 GLN 167 181 181 GLN GLN A . n 
A 1 168 ILE 168 182 182 ILE ILE A . n 
A 1 169 ASP 169 183 183 ASP ASP A . n 
A 1 170 VAL 170 184 184 VAL VAL A . n 
A 1 171 LYS 171 185 185 LYS LYS A . n 
A 1 172 ASP 172 186 186 ASP ASP A . n 
A 1 173 SER 173 187 187 SER SER A . n 
A 1 174 LYS 174 188 188 LYS LYS A . n 
A 1 175 LEU 175 189 189 LEU LEU A . n 
A 1 176 THR 176 190 190 THR THR A . n 
A 1 177 ILE 177 191 191 ILE ILE A . n 
A 1 178 THR 178 192 192 THR THR A . n 
A 1 179 VAL 179 193 193 VAL VAL A . n 
A 1 180 ASN 180 194 194 ASN ASN A . n 
A 1 181 GLY 181 195 195 GLY GLY A . n 
A 1 182 ASN 182 196 196 ASN ASN A . n 
A 1 183 VAL 183 197 197 VAL VAL A . n 
A 1 184 VAL 184 198 198 VAL VAL A . n 
A 1 185 VAL 185 199 199 VAL VAL A . n 
A 1 186 ASN 186 200 200 ASN ASN A . n 
A 1 187 GLY 187 201 201 GLY GLY A . n 
A 1 188 GLN 188 202 202 GLN GLN A . n 
A 1 189 ASP 189 203 203 ASP ASP A . n 
A 1 190 LEU 190 204 204 LEU LEU A . n 
A 1 191 SER 191 205 205 SER SER A . n 
A 1 192 PHE 192 206 206 PHE PHE A . n 
A 1 193 TRP 193 207 207 TRP TRP A . n 
A 1 194 ASP 194 208 208 ASP ASP A . n 
A 1 195 GLY 195 209 209 GLY GLY A . n 
A 1 196 THR 196 210 210 THR THR A . n 
A 1 197 ASP 197 211 211 ASP ASP A . n 
A 1 198 SER 198 212 212 SER SER A . n 
A 1 199 CYS 199 213 213 CYS CYS A . n 
A 1 200 TYR 200 214 214 TYR TYR A . n 
A 1 201 PHE 201 215 215 PHE PHE A . n 
A 1 202 LYS 202 216 216 LYS LYS A . n 
A 1 203 ALA 203 217 217 ALA ALA A . n 
A 1 204 GLY 204 218 218 GLY GLY A . n 
A 1 205 ALA 205 219 219 ALA ALA A . n 
A 1 206 TYR 206 220 220 TYR TYR A . n 
A 1 207 ASN 207 221 221 ASN ASN A . n 
A 1 208 ASN 208 222 222 ASN ASN A . n 
A 1 209 ASN 209 223 223 ASN ASN A . n 
A 1 210 PRO 210 224 224 PRO PRO A . n 
A 1 211 THR 211 225 225 THR THR A . n 
A 1 212 SER 212 226 226 SER SER A . n 
A 1 213 GLU 213 227 227 GLU GLU A . n 
A 1 214 SER 214 228 228 SER SER A . n 
A 1 215 ALA 215 229 229 ALA ALA A . n 
A 1 216 THR 216 230 230 THR THR A . n 
A 1 217 ALA 217 231 231 ALA ALA A . n 
A 1 218 ARG 218 232 232 ARG ARG A . n 
A 1 219 ILE 219 233 233 ILE ILE A . n 
A 1 220 LYS 220 234 234 LYS LYS A . n 
A 1 221 PHE 221 235 235 PHE PHE A . n 
A 1 222 ALA 222 236 236 ALA ALA A . n 
A 1 223 ALA 223 237 237 ALA ALA A . n 
A 1 224 LEU 224 238 238 LEU LEU A . n 
A 1 225 ALA 225 239 239 ALA ALA A . n 
A 1 226 TRP 226 240 240 TRP TRP A . n 
A 1 227 VAL 227 241 241 VAL VAL A . n 
A 1 228 ASP 228 242 242 ASP ASP A . n 
A 1 229 HIS 229 243 243 HIS HIS A . n 
A 1 230 HIS 230 244 ?   ?   ?   A . n 
A 1 231 HIS 231 245 ?   ?   ?   A . n 
A 1 232 HIS 232 246 ?   ?   ?   A . n 
A 1 233 HIS 233 247 ?   ?   ?   A . n 
A 1 234 HIS 234 248 ?   ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
B 2 BEM 1 B BEM 1 A BEM 322 n 
B 2 LGU 2 B LGU 2 A LGU 321 n 
B 2 BEM 3 B BEM 3 A BEM 319 n 
B 2 BEM 4 B BEM 4 A BEM 318 n 
B 2 BEM 5 B BEM 5 A BEM 317 n 
B 2 BEM 6 B BEM 6 A BEM 316 n 
C 3 BEM 1 C BEM 1 A BEM 323 n 
C 3 BEM 2 C BEM 2 A BEM 324 n 
C 3 BEM 3 C BEM 3 A BEM 325 n 
C 3 BEM 4 C BEM 4 A BEM 326 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 BEM ? ? BEM ? ? 'SUBJECT OF INVESTIGATION' ? 
2 LGU ? ? LGU ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 HOH 1   301 220 HOH HOH A . 
D 4 HOH 2   302 358 HOH HOH A . 
D 4 HOH 3   303 309 HOH HOH A . 
D 4 HOH 4   304 343 HOH HOH A . 
D 4 HOH 5   305 194 HOH HOH A . 
D 4 HOH 6   306 198 HOH HOH A . 
D 4 HOH 7   307 293 HOH HOH A . 
D 4 HOH 8   308 148 HOH HOH A . 
D 4 HOH 9   309 168 HOH HOH A . 
D 4 HOH 10  310 346 HOH HOH A . 
D 4 HOH 11  311 252 HOH HOH A . 
D 4 HOH 12  312 136 HOH HOH A . 
D 4 HOH 13  313 297 HOH HOH A . 
D 4 HOH 14  314 158 HOH HOH A . 
D 4 HOH 15  315 202 HOH HOH A . 
D 4 HOH 16  316 179 HOH HOH A . 
D 4 HOH 17  317 94  HOH HOH A . 
D 4 HOH 18  318 304 HOH HOH A . 
D 4 HOH 19  319 166 HOH HOH A . 
D 4 HOH 20  320 40  HOH HOH A . 
D 4 HOH 21  321 329 HOH HOH A . 
D 4 HOH 22  322 193 HOH HOH A . 
D 4 HOH 23  323 208 HOH HOH A . 
D 4 HOH 24  324 142 HOH HOH A . 
D 4 HOH 25  325 12  HOH HOH A . 
D 4 HOH 26  326 127 HOH HOH A . 
D 4 HOH 27  327 160 HOH HOH A . 
D 4 HOH 28  328 59  HOH HOH A . 
D 4 HOH 29  329 35  HOH HOH A . 
D 4 HOH 30  330 139 HOH HOH A . 
D 4 HOH 31  331 250 HOH HOH A . 
D 4 HOH 32  332 161 HOH HOH A . 
D 4 HOH 33  333 331 HOH HOH A . 
D 4 HOH 34  334 75  HOH HOH A . 
D 4 HOH 35  335 76  HOH HOH A . 
D 4 HOH 36  336 169 HOH HOH A . 
D 4 HOH 37  337 77  HOH HOH A . 
D 4 HOH 38  338 22  HOH HOH A . 
D 4 HOH 39  339 8   HOH HOH A . 
D 4 HOH 40  340 10  HOH HOH A . 
D 4 HOH 41  341 327 HOH HOH A . 
D 4 HOH 42  342 303 HOH HOH A . 
D 4 HOH 43  343 141 HOH HOH A . 
D 4 HOH 44  344 19  HOH HOH A . 
D 4 HOH 45  345 58  HOH HOH A . 
D 4 HOH 46  346 98  HOH HOH A . 
D 4 HOH 47  347 191 HOH HOH A . 
D 4 HOH 48  348 123 HOH HOH A . 
D 4 HOH 49  349 149 HOH HOH A . 
D 4 HOH 50  350 157 HOH HOH A . 
D 4 HOH 51  351 315 HOH HOH A . 
D 4 HOH 52  352 213 HOH HOH A . 
D 4 HOH 53  353 265 HOH HOH A . 
D 4 HOH 54  354 134 HOH HOH A . 
D 4 HOH 55  355 283 HOH HOH A . 
D 4 HOH 56  356 107 HOH HOH A . 
D 4 HOH 57  357 167 HOH HOH A . 
D 4 HOH 58  358 178 HOH HOH A . 
D 4 HOH 59  359 229 HOH HOH A . 
D 4 HOH 60  360 163 HOH HOH A . 
D 4 HOH 61  361 223 HOH HOH A . 
D 4 HOH 62  362 246 HOH HOH A . 
D 4 HOH 63  363 31  HOH HOH A . 
D 4 HOH 64  364 279 HOH HOH A . 
D 4 HOH 65  365 37  HOH HOH A . 
D 4 HOH 66  366 140 HOH HOH A . 
D 4 HOH 67  367 78  HOH HOH A . 
D 4 HOH 68  368 1   HOH HOH A . 
D 4 HOH 69  369 64  HOH HOH A . 
D 4 HOH 70  370 15  HOH HOH A . 
D 4 HOH 71  371 207 HOH HOH A . 
D 4 HOH 72  372 7   HOH HOH A . 
D 4 HOH 73  373 228 HOH HOH A . 
D 4 HOH 74  374 23  HOH HOH A . 
D 4 HOH 75  375 243 HOH HOH A . 
D 4 HOH 76  376 109 HOH HOH A . 
D 4 HOH 77  377 93  HOH HOH A . 
D 4 HOH 78  378 105 HOH HOH A . 
D 4 HOH 79  379 306 HOH HOH A . 
D 4 HOH 80  380 113 HOH HOH A . 
D 4 HOH 81  381 95  HOH HOH A . 
D 4 HOH 82  382 131 HOH HOH A . 
D 4 HOH 83  383 43  HOH HOH A . 
D 4 HOH 84  384 143 HOH HOH A . 
D 4 HOH 85  385 51  HOH HOH A . 
D 4 HOH 86  386 17  HOH HOH A . 
D 4 HOH 87  387 353 HOH HOH A . 
D 4 HOH 88  388 214 HOH HOH A . 
D 4 HOH 89  389 101 HOH HOH A . 
D 4 HOH 90  390 2   HOH HOH A . 
D 4 HOH 91  391 54  HOH HOH A . 
D 4 HOH 92  392 27  HOH HOH A . 
D 4 HOH 93  393 200 HOH HOH A . 
D 4 HOH 94  394 3   HOH HOH A . 
D 4 HOH 95  395 320 HOH HOH A . 
D 4 HOH 96  396 65  HOH HOH A . 
D 4 HOH 97  397 96  HOH HOH A . 
D 4 HOH 98  398 70  HOH HOH A . 
D 4 HOH 99  399 126 HOH HOH A . 
D 4 HOH 100 400 28  HOH HOH A . 
D 4 HOH 101 401 177 HOH HOH A . 
D 4 HOH 102 402 55  HOH HOH A . 
D 4 HOH 103 403 124 HOH HOH A . 
D 4 HOH 104 404 110 HOH HOH A . 
D 4 HOH 105 405 32  HOH HOH A . 
D 4 HOH 106 406 41  HOH HOH A . 
D 4 HOH 107 407 11  HOH HOH A . 
D 4 HOH 108 408 72  HOH HOH A . 
D 4 HOH 109 409 106 HOH HOH A . 
D 4 HOH 110 410 181 HOH HOH A . 
D 4 HOH 111 411 60  HOH HOH A . 
D 4 HOH 112 412 20  HOH HOH A . 
D 4 HOH 113 413 4   HOH HOH A . 
D 4 HOH 114 414 13  HOH HOH A . 
D 4 HOH 115 415 138 HOH HOH A . 
D 4 HOH 116 416 188 HOH HOH A . 
D 4 HOH 117 417 129 HOH HOH A . 
D 4 HOH 118 418 276 HOH HOH A . 
D 4 HOH 119 419 108 HOH HOH A . 
D 4 HOH 120 420 24  HOH HOH A . 
D 4 HOH 121 421 83  HOH HOH A . 
D 4 HOH 122 422 34  HOH HOH A . 
D 4 HOH 123 423 151 HOH HOH A . 
D 4 HOH 124 424 18  HOH HOH A . 
D 4 HOH 125 425 82  HOH HOH A . 
D 4 HOH 126 426 5   HOH HOH A . 
D 4 HOH 127 427 310 HOH HOH A . 
D 4 HOH 128 428 26  HOH HOH A . 
D 4 HOH 129 429 125 HOH HOH A . 
D 4 HOH 130 430 164 HOH HOH A . 
D 4 HOH 131 431 71  HOH HOH A . 
D 4 HOH 132 432 354 HOH HOH A . 
D 4 HOH 133 433 174 HOH HOH A . 
D 4 HOH 134 434 122 HOH HOH A . 
D 4 HOH 135 435 52  HOH HOH A . 
D 4 HOH 136 436 38  HOH HOH A . 
D 4 HOH 137 437 286 HOH HOH A . 
D 4 HOH 138 438 46  HOH HOH A . 
D 4 HOH 139 439 112 HOH HOH A . 
D 4 HOH 140 440 225 HOH HOH A . 
D 4 HOH 141 441 16  HOH HOH A . 
D 4 HOH 142 442 9   HOH HOH A . 
D 4 HOH 143 443 69  HOH HOH A . 
D 4 HOH 144 444 189 HOH HOH A . 
D 4 HOH 145 445 100 HOH HOH A . 
D 4 HOH 146 446 85  HOH HOH A . 
D 4 HOH 147 447 325 HOH HOH A . 
D 4 HOH 148 448 62  HOH HOH A . 
D 4 HOH 149 449 135 HOH HOH A . 
D 4 HOH 150 450 42  HOH HOH A . 
D 4 HOH 151 451 121 HOH HOH A . 
D 4 HOH 152 452 79  HOH HOH A . 
D 4 HOH 153 453 180 HOH HOH A . 
D 4 HOH 154 454 280 HOH HOH A . 
D 4 HOH 155 455 68  HOH HOH A . 
D 4 HOH 156 456 319 HOH HOH A . 
D 4 HOH 157 457 205 HOH HOH A . 
D 4 HOH 158 458 204 HOH HOH A . 
D 4 HOH 159 459 61  HOH HOH A . 
D 4 HOH 160 460 185 HOH HOH A . 
D 4 HOH 161 461 226 HOH HOH A . 
D 4 HOH 162 462 175 HOH HOH A . 
D 4 HOH 163 463 6   HOH HOH A . 
D 4 HOH 164 464 278 HOH HOH A . 
D 4 HOH 165 465 117 HOH HOH A . 
D 4 HOH 166 466 92  HOH HOH A . 
D 4 HOH 167 467 183 HOH HOH A . 
D 4 HOH 168 468 288 HOH HOH A . 
D 4 HOH 169 469 130 HOH HOH A . 
D 4 HOH 170 470 29  HOH HOH A . 
D 4 HOH 171 471 53  HOH HOH A . 
D 4 HOH 172 472 145 HOH HOH A . 
D 4 HOH 173 473 187 HOH HOH A . 
D 4 HOH 174 474 119 HOH HOH A . 
D 4 HOH 175 475 128 HOH HOH A . 
D 4 HOH 176 476 176 HOH HOH A . 
D 4 HOH 177 477 262 HOH HOH A . 
D 4 HOH 178 478 184 HOH HOH A . 
D 4 HOH 179 479 115 HOH HOH A . 
D 4 HOH 180 480 87  HOH HOH A . 
D 4 HOH 181 481 66  HOH HOH A . 
D 4 HOH 182 482 339 HOH HOH A . 
D 4 HOH 183 483 295 HOH HOH A . 
D 4 HOH 184 484 36  HOH HOH A . 
D 4 HOH 185 485 153 HOH HOH A . 
D 4 HOH 186 486 203 HOH HOH A . 
D 4 HOH 187 487 170 HOH HOH A . 
D 4 HOH 188 488 33  HOH HOH A . 
D 4 HOH 189 489 267 HOH HOH A . 
D 4 HOH 190 490 25  HOH HOH A . 
D 4 HOH 191 491 97  HOH HOH A . 
D 4 HOH 192 492 206 HOH HOH A . 
D 4 HOH 193 493 67  HOH HOH A . 
D 4 HOH 194 494 45  HOH HOH A . 
D 4 HOH 195 495 84  HOH HOH A . 
D 4 HOH 196 496 86  HOH HOH A . 
D 4 HOH 197 497 133 HOH HOH A . 
D 4 HOH 198 498 326 HOH HOH A . 
D 4 HOH 199 499 90  HOH HOH A . 
D 4 HOH 200 500 21  HOH HOH A . 
D 4 HOH 201 501 253 HOH HOH A . 
D 4 HOH 202 502 73  HOH HOH A . 
D 4 HOH 203 503 39  HOH HOH A . 
D 4 HOH 204 504 196 HOH HOH A . 
D 4 HOH 205 505 132 HOH HOH A . 
D 4 HOH 206 506 217 HOH HOH A . 
D 4 HOH 207 507 356 HOH HOH A . 
D 4 HOH 208 508 91  HOH HOH A . 
D 4 HOH 209 509 147 HOH HOH A . 
D 4 HOH 210 510 114 HOH HOH A . 
D 4 HOH 211 511 154 HOH HOH A . 
D 4 HOH 212 512 120 HOH HOH A . 
D 4 HOH 213 513 345 HOH HOH A . 
D 4 HOH 214 514 162 HOH HOH A . 
D 4 HOH 215 515 14  HOH HOH A . 
D 4 HOH 216 516 201 HOH HOH A . 
D 4 HOH 217 517 239 HOH HOH A . 
D 4 HOH 218 518 118 HOH HOH A . 
D 4 HOH 219 519 80  HOH HOH A . 
D 4 HOH 220 520 56  HOH HOH A . 
D 4 HOH 221 521 270 HOH HOH A . 
D 4 HOH 222 522 292 HOH HOH A . 
D 4 HOH 223 523 44  HOH HOH A . 
D 4 HOH 224 524 321 HOH HOH A . 
D 4 HOH 225 525 248 HOH HOH A . 
D 4 HOH 226 526 290 HOH HOH A . 
D 4 HOH 227 527 317 HOH HOH A . 
D 4 HOH 228 528 57  HOH HOH A . 
D 4 HOH 229 529 190 HOH HOH A . 
D 4 HOH 230 530 316 HOH HOH A . 
D 4 HOH 231 531 341 HOH HOH A . 
D 4 HOH 232 532 301 HOH HOH A . 
D 4 HOH 233 533 271 HOH HOH A . 
D 4 HOH 234 534 255 HOH HOH A . 
D 4 HOH 235 535 230 HOH HOH A . 
D 4 HOH 236 536 273 HOH HOH A . 
D 4 HOH 237 537 264 HOH HOH A . 
D 4 HOH 238 538 266 HOH HOH A . 
D 4 HOH 239 539 296 HOH HOH A . 
D 4 HOH 240 540 256 HOH HOH A . 
D 4 HOH 241 541 146 HOH HOH A . 
D 4 HOH 242 542 314 HOH HOH A . 
D 4 HOH 243 543 352 HOH HOH A . 
D 4 HOH 244 544 173 HOH HOH A . 
D 4 HOH 245 545 156 HOH HOH A . 
D 4 HOH 246 546 221 HOH HOH A . 
D 4 HOH 247 547 195 HOH HOH A . 
D 4 HOH 248 548 254 HOH HOH A . 
D 4 HOH 249 549 332 HOH HOH A . 
D 4 HOH 250 550 102 HOH HOH A . 
D 4 HOH 251 551 199 HOH HOH A . 
D 4 HOH 252 552 342 HOH HOH A . 
D 4 HOH 253 553 224 HOH HOH A . 
D 4 HOH 254 554 215 HOH HOH A . 
D 4 HOH 255 555 257 HOH HOH A . 
D 4 HOH 256 556 302 HOH HOH A . 
D 4 HOH 257 557 289 HOH HOH A . 
D 4 HOH 258 558 322 HOH HOH A . 
D 4 HOH 259 559 103 HOH HOH A . 
D 4 HOH 260 560 186 HOH HOH A . 
D 4 HOH 261 561 357 HOH HOH A . 
D 4 HOH 262 562 263 HOH HOH A . 
D 4 HOH 263 563 333 HOH HOH A . 
D 4 HOH 264 564 287 HOH HOH A . 
D 4 HOH 265 565 212 HOH HOH A . 
D 4 HOH 266 566 241 HOH HOH A . 
D 4 HOH 267 567 47  HOH HOH A . 
D 4 HOH 268 568 150 HOH HOH A . 
D 4 HOH 269 569 272 HOH HOH A . 
D 4 HOH 270 570 216 HOH HOH A . 
D 4 HOH 271 571 299 HOH HOH A . 
D 4 HOH 272 572 30  HOH HOH A . 
D 4 HOH 273 573 323 HOH HOH A . 
D 4 HOH 274 574 311 HOH HOH A . 
D 4 HOH 275 575 99  HOH HOH A . 
D 4 HOH 276 576 347 HOH HOH A . 
D 4 HOH 277 577 81  HOH HOH A . 
D 4 HOH 278 578 222 HOH HOH A . 
D 4 HOH 279 579 192 HOH HOH A . 
D 4 HOH 280 580 324 HOH HOH A . 
D 4 HOH 281 581 63  HOH HOH A . 
D 4 HOH 282 582 137 HOH HOH A . 
D 4 HOH 283 583 245 HOH HOH A . 
D 4 HOH 284 584 50  HOH HOH A . 
D 4 HOH 285 585 284 HOH HOH A . 
D 4 HOH 286 586 237 HOH HOH A . 
D 4 HOH 287 587 291 HOH HOH A . 
D 4 HOH 288 588 348 HOH HOH A . 
D 4 HOH 289 589 227 HOH HOH A . 
D 4 HOH 290 590 211 HOH HOH A . 
D 4 HOH 291 591 171 HOH HOH A . 
D 4 HOH 292 592 234 HOH HOH A . 
D 4 HOH 293 593 89  HOH HOH A . 
D 4 HOH 294 594 155 HOH HOH A . 
D 4 HOH 295 595 111 HOH HOH A . 
D 4 HOH 296 596 210 HOH HOH A . 
D 4 HOH 297 597 104 HOH HOH A . 
D 4 HOH 298 598 336 HOH HOH A . 
D 4 HOH 299 599 231 HOH HOH A . 
D 4 HOH 300 600 275 HOH HOH A . 
D 4 HOH 301 601 307 HOH HOH A . 
D 4 HOH 302 602 240 HOH HOH A . 
D 4 HOH 303 603 300 HOH HOH A . 
D 4 HOH 304 604 344 HOH HOH A . 
D 4 HOH 305 605 251 HOH HOH A . 
D 4 HOH 306 606 116 HOH HOH A . 
D 4 HOH 307 607 182 HOH HOH A . 
D 4 HOH 308 608 340 HOH HOH A . 
D 4 HOH 309 609 209 HOH HOH A . 
D 4 HOH 310 610 338 HOH HOH A . 
D 4 HOH 311 611 49  HOH HOH A . 
D 4 HOH 312 612 260 HOH HOH A . 
D 4 HOH 313 613 313 HOH HOH A . 
D 4 HOH 314 614 144 HOH HOH A . 
D 4 HOH 315 615 197 HOH HOH A . 
D 4 HOH 316 616 165 HOH HOH A . 
D 4 HOH 317 617 152 HOH HOH A . 
D 4 HOH 318 618 281 HOH HOH A . 
D 4 HOH 319 619 351 HOH HOH A . 
D 4 HOH 320 620 238 HOH HOH A . 
D 4 HOH 321 621 294 HOH HOH A . 
D 4 HOH 322 622 74  HOH HOH A . 
D 4 HOH 323 623 330 HOH HOH A . 
D 4 HOH 324 624 350 HOH HOH A . 
D 4 HOH 325 625 88  HOH HOH A . 
D 4 HOH 326 626 159 HOH HOH A . 
D 4 HOH 327 627 219 HOH HOH A . 
D 4 HOH 328 628 355 HOH HOH A . 
D 4 HOH 329 629 232 HOH HOH A . 
D 4 HOH 330 630 312 HOH HOH A . 
D 4 HOH 331 631 236 HOH HOH A . 
D 4 HOH 332 632 242 HOH HOH A . 
D 4 HOH 333 633 48  HOH HOH A . 
D 4 HOH 334 634 233 HOH HOH A . 
D 4 HOH 335 635 308 HOH HOH A . 
D 4 HOH 336 636 337 HOH HOH A . 
D 4 HOH 337 637 285 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 0 A ASN 75  ? CA  A A ASN 61 CA  
2  1 Y 0 A ASN 75  ? CB  A A ASN 61 CB  
3  1 Y 0 A ASN 75  ? CG  A A ASN 61 CG  
4  1 Y 0 A ASN 75  ? OD1 A A ASN 61 OD1 
5  1 Y 0 A ASN 75  ? ND2 A A ASN 61 ND2 
6  1 Y 0 A PRO 109 ? N   B A PRO 95 N   
7  1 Y 0 A PRO 109 ? CA  B A PRO 95 CA  
8  1 Y 0 A PRO 109 ? C   B A PRO 95 C   
9  1 Y 0 A PRO 109 ? O   B A PRO 95 O   
10 1 Y 0 A PRO 109 ? CB  B A PRO 95 CB  
11 1 Y 0 A PRO 109 ? CG  B A PRO 95 CG  
12 1 Y 0 A PRO 109 ? CD  B A PRO 95 CD  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? dev_4788 1 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? MxCuBE ? ? ? 3        2 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        4 
? 'model building'  ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? .        5 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .        6 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   114.640 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8QIZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     42.690 
_cell.length_a_esd                 ? 
_cell.length_b                     69.360 
_cell.length_b_esd                 ? 
_cell.length_c                     42.920 
_cell.length_c_esd                 ? 
_cell.volume                       115513.485 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8QIZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8QIZ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.26 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.65 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '30% PEG3350, 0.1M Bis-Tris pH 5.5, 0.2M NaCl' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            273 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-06-11 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID30B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID30B 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          13.38 
_reflns.entry_id                                       8QIZ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.13 
_reflns.d_resolution_low                               39.01 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     162684 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.94 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.57 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.13 
_reflns_shell.d_res_low                                     1.16 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4929 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.62 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.67 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8QIZ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.13 
_refine.ls_d_res_low                             39.01 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     162683 
_refine.ls_number_reflns_R_free                  2102 
_refine.ls_number_reflns_R_work                  160581 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    96.93 
_refine.ls_percent_reflns_R_free                 1.29 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1268 
_refine.ls_R_factor_R_free                       0.1585 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1264 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.24 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 18.0889 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1377 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.13 
_refine_hist.d_res_low                        39.01 
_refine_hist.number_atoms_solvent             337 
_refine_hist.number_atoms_total               2204 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1745 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         122 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0062  ? 2000 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0438  ? 2751 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0877  ? 341  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0085  ? 349  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.4045 ? 683  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.13 1.16  . . 127 9537  86.21 . . . . 0.3365 . . . . . . . . . . . 0.3222 
'X-RAY DIFFRACTION' 1.16 1.18  . . 134 10239 92.78 . . . . 0.2936 . . . . . . . . . . . 0.3373 
'X-RAY DIFFRACTION' 1.18 1.22  . . 139 10512 95.06 . . . . 0.2400 . . . . . . . . . . . 0.2323 
'X-RAY DIFFRACTION' 1.22 1.25  . . 135 10557 95.88 . . . . 0.2051 . . . . . . . . . . . 0.2672 
'X-RAY DIFFRACTION' 1.25 1.29  . . 140 10784 97.34 . . . . 0.1756 . . . . . . . . . . . 0.1599 
'X-RAY DIFFRACTION' 1.29 1.34  . . 140 10788 97.93 . . . . 0.1633 . . . . . . . . . . . 0.1671 
'X-RAY DIFFRACTION' 1.34 1.39  . . 140 10898 98.77 . . . . 0.1485 . . . . . . . . . . . 0.2061 
'X-RAY DIFFRACTION' 1.39 1.46  . . 142 10899 98.96 . . . . 0.1343 . . . . . . . . . . . 0.1652 
'X-RAY DIFFRACTION' 1.46 1.53  . . 145 11067 99.04 . . . . 0.1063 . . . . . . . . . . . 0.1254 
'X-RAY DIFFRACTION' 1.53 1.63  . . 144 10900 99.28 . . . . 0.0988 . . . . . . . . . . . 0.1334 
'X-RAY DIFFRACTION' 1.63 1.75  . . 144 10936 99.61 . . . . 0.0992 . . . . . . . . . . . 0.1335 
'X-RAY DIFFRACTION' 1.75 1.93  . . 145 10987 98.95 . . . . 0.1135 . . . . . . . . . . . 0.1370 
'X-RAY DIFFRACTION' 1.93 2.21  . . 141 10864 98.41 . . . . 0.1098 . . . . . . . . . . . 0.1285 
'X-RAY DIFFRACTION' 2.21 2.79  . . 141 10783 97.82 . . . . 0.1191 . . . . . . . . . . . 0.1426 
'X-RAY DIFFRACTION' 2.79 39.01 . . 145 10830 97.92 . . . . 0.1138 . . . . . . . . . . . 0.1649 
# 
_struct.entry_id                     8QIZ 
_struct.title                        
'Crystal structure of Paradendryphiella salina PL7C alginate lyase mutant H124N soaked with with penta-mannuronic acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8QIZ 
_struct_keywords.text            'Beta-jelly roll, alginate lyase, complex, LYASE' 
_struct_keywords.pdbx_keywords   LYASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7I9C8Z1_9PLEO 
_struct_ref.pdbx_db_accession          A0A7I9C8Z1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;LTAVSSIDTFLPVLNEAKLQWPTSALAASSEELLGGYVGSQFYLQDGKYMQFQIAGSSNRCELRQMIPDGGSEIGWAVDD
GTTHTATSSIVVPEQVDGVEEVTIMQIHSGEAPQLRISWIRSKSLDGVAYEDFIMSTVRIGTGDSSDNFVKTHLADRTAG
AMSFQIDVKDSKLTITVNGNVVVNGQDLSFWDGTDSCYFKAGAYNNNPTSESATARIKFAALAW
;
_struct_ref.pdbx_align_begin           17 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8QIZ 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 226 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A7I9C8Z1 
_struct_ref_seq.db_align_beg                  17 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  240 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       17 
_struct_ref_seq.pdbx_auth_seq_align_end       240 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8QIZ GLU A 1   ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      15  1  
1 8QIZ PHE A 2   ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      16  2  
1 8QIZ ASN A 110 ? UNP A0A7I9C8Z1 HIS 124 'engineered mutation' 124 3  
1 8QIZ VAL A 227 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      241 4  
1 8QIZ ASP A 228 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      242 5  
1 8QIZ HIS A 229 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      243 6  
1 8QIZ HIS A 230 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      244 7  
1 8QIZ HIS A 231 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      245 8  
1 8QIZ HIS A 232 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      246 9  
1 8QIZ HIS A 233 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      247 10 
1 8QIZ HIS A 234 ? UNP A0A7I9C8Z1 ?   ?   'expression tag'      248 11 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3290 ? 
1 MORE         27   ? 
1 'SSA (A^2)'  9370 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ALA A 5   ? ILE A 9   ? ALA A 19  ILE A 23  5 ? 5 
HELX_P HELX_P2 AA2 PHE A 12  ? ASN A 17  ? PHE A 26  ASN A 31  1 ? 6 
HELX_P HELX_P3 AA3 SER A 31  ? GLY A 37  ? SER A 45  GLY A 51  1 ? 7 
HELX_P HELX_P4 AA4 SER A 147 ? ASP A 149 ? SER A 161 ASP A 163 5 ? 3 
HELX_P HELX_P5 AA5 SER A 191 ? ASP A 194 ? SER A 205 ASP A 208 5 ? 4 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? B BEM . O4 ? ? ? 1_555 B LGU . C1 ? ? B BEM 1 B LGU 2 1_555 ? ? ? ? ? ? ? 1.435 ? ? 
covale2 covale both ? B LGU . O4 ? ? ? 1_555 B BEM . C1 ? ? B LGU 2 B BEM 3 1_555 ? ? ? ? ? ? ? 1.413 ? ? 
covale3 covale both ? B BEM . O4 ? ? ? 1_555 B BEM . C1 ? ? B BEM 3 B BEM 4 1_555 ? ? ? ? ? ? ? 1.446 ? ? 
covale4 covale both ? B BEM . O4 ? ? ? 1_555 B BEM . C1 ? ? B BEM 4 B BEM 5 1_555 ? ? ? ? ? ? ? 1.432 ? ? 
covale5 covale both ? B BEM . O4 ? ? ? 1_555 B BEM . C1 ? ? B BEM 5 B BEM 6 1_555 ? ? ? ? ? ? ? 1.420 ? ? 
covale6 covale both ? C BEM . O4 ? ? ? 1_555 C BEM . C1 ? ? C BEM 1 C BEM 2 1_555 ? ? ? ? ? ? ? 1.425 ? ? 
covale7 covale both ? C BEM . O4 ? ? ? 1_555 C BEM . C1 ? ? C BEM 2 C BEM 3 1_555 ? ? ? ? ? ? ? 1.427 ? ? 
covale8 covale both ? C BEM . O4 ? ? ? 1_555 C BEM . C1 ? ? C BEM 3 C BEM 4 1_555 ? ? ? ? ? ? ? 1.429 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TRP 
_struct_mon_prot_cis.label_seq_id           23 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TRP 
_struct_mon_prot_cis.auth_seq_id            37 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    24 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     38 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -5.42 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 28  ? ALA A 30  ? LEU A 42  ALA A 44  
AA1 2 ALA A 19  ? GLN A 22  ? ALA A 33  GLN A 36  
AA1 3 ARG A 62  ? GLN A 67  ? ARG A 76  GLN A 81  
AA1 4 TYR A 200 ? ASN A 207 ? TYR A 214 ASN A 221 
AA1 5 GLU A 103 ? ASN A 110 ? GLU A 117 ASN A 124 
AA1 6 LEU A 117 ? LEU A 127 ? LEU A 131 LEU A 141 
AA1 7 VAL A 130 ? ARG A 141 ? VAL A 144 ARG A 155 
AA1 8 PHE A 151 ? ASP A 158 ? PHE A 165 ASP A 172 
AA2 1 PHE A 44  ? GLN A 47  ? PHE A 58  GLN A 61  
AA2 2 TYR A 51  ? ALA A 57  ? TYR A 65  ALA A 71  
AA2 3 THR A 216 ? VAL A 227 ? THR A 230 VAL A 241 
AA2 4 HIS A 86  ? VAL A 93  ? HIS A 100 VAL A 107 
AA2 5 MET A 164 ? LYS A 171 ? MET A 178 LYS A 185 
AA2 6 LYS A 174 ? VAL A 179 ? LYS A 188 VAL A 193 
AA2 7 ASN A 182 ? ASP A 189 ? ASN A 196 ASP A 203 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 29  ? O ALA A 43  N LEU A 21  ? N LEU A 35  
AA1 2 3 N GLN A 22  ? N GLN A 36  O GLU A 64  ? O GLU A 78  
AA1 3 4 N LEU A 65  ? N LEU A 79  O ALA A 203 ? O ALA A 217 
AA1 4 5 O TYR A 206 ? O TYR A 220 N THR A 105 ? N THR A 119 
AA1 5 6 N MET A 107 ? N MET A 121 O ILE A 119 ? O ILE A 133 
AA1 6 7 N SER A 120 ? N SER A 134 O MET A 137 ? O MET A 151 
AA1 7 8 N ILE A 136 ? N ILE A 150 O ALA A 157 ? O ALA A 171 
AA2 1 2 N GLN A 47  ? N GLN A 61  O TYR A 51  ? O TYR A 65  
AA2 2 3 N MET A 52  ? N MET A 66  O PHE A 221 ? O PHE A 235 
AA2 3 4 O LYS A 220 ? O LYS A 234 N VAL A 93  ? N VAL A 107 
AA2 4 5 N ALA A 88  ? N ALA A 102 O ILE A 168 ? O ILE A 182 
AA2 5 6 N ASP A 169 ? N ASP A 183 O THR A 176 ? O THR A 190 
AA2 6 7 N ILE A 177 ? N ILE A 191 O VAL A 184 ? O VAL A 198 
# 
_pdbx_entry_details.entry_id                   8QIZ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HG  A SER 161 ? ? OD1 A ASP 163 ? ? 1.56 
2  1 HO1 C BEM 1   ? ? O   A HOH 619 ? ? 1.59 
3  1 O   A HOH 318 ? ? O   A HOH 529 ? ? 1.89 
4  1 O   A HOH 310 ? ? O   A HOH 459 ? ? 1.91 
5  1 O   A HOH 364 ? ? O   A HOH 497 ? ? 1.93 
6  1 O   A HOH 534 ? ? O   A HOH 624 ? ? 1.95 
7  1 O   A HOH 319 ? ? O   A HOH 492 ? ? 2.01 
8  1 O   A HOH 308 ? ? O   A HOH 556 ? ? 2.04 
9  1 O   A HOH 304 ? ? O   A HOH 397 ? ? 2.04 
10 1 O   A HOH 342 ? ? O   A HOH 451 ? ? 2.06 
11 1 O   A HOH 305 ? ? O   A HOH 528 ? ? 2.08 
12 1 O1  C BEM 1   ? ? O   A HOH 619 ? ? 2.12 
13 1 OG  A SER 161 ? ? OD1 A ASP 163 ? ? 2.16 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 304 ? ? 1_555 O A HOH 312 ? ? 1_556 1.99 
2 1 O A HOH 437 ? ? 1_555 O A HOH 618 ? ? 1_455 2.00 
3 1 O A HOH 527 ? ? 1_555 O A HOH 583 ? ? 1_455 2.03 
4 1 O A HOH 591 ? ? 1_555 O A HOH 636 ? ? 1_656 2.05 
5 1 O A HOH 333 ? ? 1_555 O A HOH 432 ? ? 1_454 2.17 
6 1 O A HOH 519 ? ? 1_555 O A HOH 574 ? ? 1_655 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 THR A 39  ? ? -127.94 -159.20 
2 1 LYS A 64  ? ? -150.68 -13.41  
3 1 ALA A 171 ? ? -171.80 148.97  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 632 ? 6.73 . 
2 1 O ? A HOH 633 ? 6.75 . 
3 1 O ? A HOH 636 ? 8.26 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A HIS 244 ? A HIS 230 
2 1 Y 1 A HIS 245 ? A HIS 231 
3 1 Y 1 A HIS 246 ? A HIS 232 
4 1 Y 1 A HIS 247 ? A HIS 233 
5 1 Y 1 A HIS 248 ? A HIS 234 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BEM C1   C N R 74  
BEM C2   C N S 75  
BEM O2   O N N 76  
BEM C3   C N S 77  
BEM O3   O N N 78  
BEM C4   C N S 79  
BEM O4   O N N 80  
BEM C5   C N S 81  
BEM O5   O N N 82  
BEM C6   C N N 83  
BEM O6B  O N N 84  
BEM O6A  O N N 85  
BEM O1   O N N 86  
BEM H1   H N N 87  
BEM H2   H N N 88  
BEM HO2  H N N 89  
BEM H3   H N N 90  
BEM HO3  H N N 91  
BEM H4   H N N 92  
BEM HO4  H N N 93  
BEM H5   H N N 94  
BEM HO1  H N N 95  
BEM HO6B H N N 96  
CYS N    N N N 97  
CYS CA   C N R 98  
CYS C    C N N 99  
CYS O    O N N 100 
CYS CB   C N N 101 
CYS SG   S N N 102 
CYS OXT  O N N 103 
CYS H    H N N 104 
CYS H2   H N N 105 
CYS HA   H N N 106 
CYS HB2  H N N 107 
CYS HB3  H N N 108 
CYS HG   H N N 109 
CYS HXT  H N N 110 
GLN N    N N N 111 
GLN CA   C N S 112 
GLN C    C N N 113 
GLN O    O N N 114 
GLN CB   C N N 115 
GLN CG   C N N 116 
GLN CD   C N N 117 
GLN OE1  O N N 118 
GLN NE2  N N N 119 
GLN OXT  O N N 120 
GLN H    H N N 121 
GLN H2   H N N 122 
GLN HA   H N N 123 
GLN HB2  H N N 124 
GLN HB3  H N N 125 
GLN HG2  H N N 126 
GLN HG3  H N N 127 
GLN HE21 H N N 128 
GLN HE22 H N N 129 
GLN HXT  H N N 130 
GLU N    N N N 131 
GLU CA   C N S 132 
GLU C    C N N 133 
GLU O    O N N 134 
GLU CB   C N N 135 
GLU CG   C N N 136 
GLU CD   C N N 137 
GLU OE1  O N N 138 
GLU OE2  O N N 139 
GLU OXT  O N N 140 
GLU H    H N N 141 
GLU H2   H N N 142 
GLU HA   H N N 143 
GLU HB2  H N N 144 
GLU HB3  H N N 145 
GLU HG2  H N N 146 
GLU HG3  H N N 147 
GLU HE2  H N N 148 
GLU HXT  H N N 149 
GLY N    N N N 150 
GLY CA   C N N 151 
GLY C    C N N 152 
GLY O    O N N 153 
GLY OXT  O N N 154 
GLY H    H N N 155 
GLY H2   H N N 156 
GLY HA2  H N N 157 
GLY HA3  H N N 158 
GLY HXT  H N N 159 
HIS N    N N N 160 
HIS CA   C N S 161 
HIS C    C N N 162 
HIS O    O N N 163 
HIS CB   C N N 164 
HIS CG   C Y N 165 
HIS ND1  N Y N 166 
HIS CD2  C Y N 167 
HIS CE1  C Y N 168 
HIS NE2  N Y N 169 
HIS OXT  O N N 170 
HIS H    H N N 171 
HIS H2   H N N 172 
HIS HA   H N N 173 
HIS HB2  H N N 174 
HIS HB3  H N N 175 
HIS HD1  H N N 176 
HIS HD2  H N N 177 
HIS HE1  H N N 178 
HIS HE2  H N N 179 
HIS HXT  H N N 180 
HOH O    O N N 181 
HOH H1   H N N 182 
HOH H2   H N N 183 
ILE N    N N N 184 
ILE CA   C N S 185 
ILE C    C N N 186 
ILE O    O N N 187 
ILE CB   C N S 188 
ILE CG1  C N N 189 
ILE CG2  C N N 190 
ILE CD1  C N N 191 
ILE OXT  O N N 192 
ILE H    H N N 193 
ILE H2   H N N 194 
ILE HA   H N N 195 
ILE HB   H N N 196 
ILE HG12 H N N 197 
ILE HG13 H N N 198 
ILE HG21 H N N 199 
ILE HG22 H N N 200 
ILE HG23 H N N 201 
ILE HD11 H N N 202 
ILE HD12 H N N 203 
ILE HD13 H N N 204 
ILE HXT  H N N 205 
LEU N    N N N 206 
LEU CA   C N S 207 
LEU C    C N N 208 
LEU O    O N N 209 
LEU CB   C N N 210 
LEU CG   C N N 211 
LEU CD1  C N N 212 
LEU CD2  C N N 213 
LEU OXT  O N N 214 
LEU H    H N N 215 
LEU H2   H N N 216 
LEU HA   H N N 217 
LEU HB2  H N N 218 
LEU HB3  H N N 219 
LEU HG   H N N 220 
LEU HD11 H N N 221 
LEU HD12 H N N 222 
LEU HD13 H N N 223 
LEU HD21 H N N 224 
LEU HD22 H N N 225 
LEU HD23 H N N 226 
LEU HXT  H N N 227 
LGU C1   C N R 228 
LGU C2   C N S 229 
LGU O2   O N N 230 
LGU C3   C N S 231 
LGU O3   O N N 232 
LGU C4   C N S 233 
LGU O4   O N N 234 
LGU C5   C N R 235 
LGU O5   O N N 236 
LGU C6   C N N 237 
LGU O6B  O N N 238 
LGU O6A  O N N 239 
LGU O1   O N N 240 
LGU H1   H N N 241 
LGU H2   H N N 242 
LGU HO2  H N N 243 
LGU H3   H N N 244 
LGU HO3  H N N 245 
LGU H4   H N N 246 
LGU HO4  H N N 247 
LGU H5   H N N 248 
LGU HO6B H N N 249 
LGU HO1  H N N 250 
LYS N    N N N 251 
LYS CA   C N S 252 
LYS C    C N N 253 
LYS O    O N N 254 
LYS CB   C N N 255 
LYS CG   C N N 256 
LYS CD   C N N 257 
LYS CE   C N N 258 
LYS NZ   N N N 259 
LYS OXT  O N N 260 
LYS H    H N N 261 
LYS H2   H N N 262 
LYS HA   H N N 263 
LYS HB2  H N N 264 
LYS HB3  H N N 265 
LYS HG2  H N N 266 
LYS HG3  H N N 267 
LYS HD2  H N N 268 
LYS HD3  H N N 269 
LYS HE2  H N N 270 
LYS HE3  H N N 271 
LYS HZ1  H N N 272 
LYS HZ2  H N N 273 
LYS HZ3  H N N 274 
LYS HXT  H N N 275 
MET N    N N N 276 
MET CA   C N S 277 
MET C    C N N 278 
MET O    O N N 279 
MET CB   C N N 280 
MET CG   C N N 281 
MET SD   S N N 282 
MET CE   C N N 283 
MET OXT  O N N 284 
MET H    H N N 285 
MET H2   H N N 286 
MET HA   H N N 287 
MET HB2  H N N 288 
MET HB3  H N N 289 
MET HG2  H N N 290 
MET HG3  H N N 291 
MET HE1  H N N 292 
MET HE2  H N N 293 
MET HE3  H N N 294 
MET HXT  H N N 295 
PHE N    N N N 296 
PHE CA   C N S 297 
PHE C    C N N 298 
PHE O    O N N 299 
PHE CB   C N N 300 
PHE CG   C Y N 301 
PHE CD1  C Y N 302 
PHE CD2  C Y N 303 
PHE CE1  C Y N 304 
PHE CE2  C Y N 305 
PHE CZ   C Y N 306 
PHE OXT  O N N 307 
PHE H    H N N 308 
PHE H2   H N N 309 
PHE HA   H N N 310 
PHE HB2  H N N 311 
PHE HB3  H N N 312 
PHE HD1  H N N 313 
PHE HD2  H N N 314 
PHE HE1  H N N 315 
PHE HE2  H N N 316 
PHE HZ   H N N 317 
PHE HXT  H N N 318 
PRO N    N N N 319 
PRO CA   C N S 320 
PRO C    C N N 321 
PRO O    O N N 322 
PRO CB   C N N 323 
PRO CG   C N N 324 
PRO CD   C N N 325 
PRO OXT  O N N 326 
PRO H    H N N 327 
PRO HA   H N N 328 
PRO HB2  H N N 329 
PRO HB3  H N N 330 
PRO HG2  H N N 331 
PRO HG3  H N N 332 
PRO HD2  H N N 333 
PRO HD3  H N N 334 
PRO HXT  H N N 335 
SER N    N N N 336 
SER CA   C N S 337 
SER C    C N N 338 
SER O    O N N 339 
SER CB   C N N 340 
SER OG   O N N 341 
SER OXT  O N N 342 
SER H    H N N 343 
SER H2   H N N 344 
SER HA   H N N 345 
SER HB2  H N N 346 
SER HB3  H N N 347 
SER HG   H N N 348 
SER HXT  H N N 349 
THR N    N N N 350 
THR CA   C N S 351 
THR C    C N N 352 
THR O    O N N 353 
THR CB   C N R 354 
THR OG1  O N N 355 
THR CG2  C N N 356 
THR OXT  O N N 357 
THR H    H N N 358 
THR H2   H N N 359 
THR HA   H N N 360 
THR HB   H N N 361 
THR HG1  H N N 362 
THR HG21 H N N 363 
THR HG22 H N N 364 
THR HG23 H N N 365 
THR HXT  H N N 366 
TRP N    N N N 367 
TRP CA   C N S 368 
TRP C    C N N 369 
TRP O    O N N 370 
TRP CB   C N N 371 
TRP CG   C Y N 372 
TRP CD1  C Y N 373 
TRP CD2  C Y N 374 
TRP NE1  N Y N 375 
TRP CE2  C Y N 376 
TRP CE3  C Y N 377 
TRP CZ2  C Y N 378 
TRP CZ3  C Y N 379 
TRP CH2  C Y N 380 
TRP OXT  O N N 381 
TRP H    H N N 382 
TRP H2   H N N 383 
TRP HA   H N N 384 
TRP HB2  H N N 385 
TRP HB3  H N N 386 
TRP HD1  H N N 387 
TRP HE1  H N N 388 
TRP HE3  H N N 389 
TRP HZ2  H N N 390 
TRP HZ3  H N N 391 
TRP HH2  H N N 392 
TRP HXT  H N N 393 
TYR N    N N N 394 
TYR CA   C N S 395 
TYR C    C N N 396 
TYR O    O N N 397 
TYR CB   C N N 398 
TYR CG   C Y N 399 
TYR CD1  C Y N 400 
TYR CD2  C Y N 401 
TYR CE1  C Y N 402 
TYR CE2  C Y N 403 
TYR CZ   C Y N 404 
TYR OH   O N N 405 
TYR OXT  O N N 406 
TYR H    H N N 407 
TYR H2   H N N 408 
TYR HA   H N N 409 
TYR HB2  H N N 410 
TYR HB3  H N N 411 
TYR HD1  H N N 412 
TYR HD2  H N N 413 
TYR HE1  H N N 414 
TYR HE2  H N N 415 
TYR HH   H N N 416 
TYR HXT  H N N 417 
VAL N    N N N 418 
VAL CA   C N S 419 
VAL C    C N N 420 
VAL O    O N N 421 
VAL CB   C N N 422 
VAL CG1  C N N 423 
VAL CG2  C N N 424 
VAL OXT  O N N 425 
VAL H    H N N 426 
VAL H2   H N N 427 
VAL HA   H N N 428 
VAL HB   H N N 429 
VAL HG11 H N N 430 
VAL HG12 H N N 431 
VAL HG13 H N N 432 
VAL HG21 H N N 433 
VAL HG22 H N N 434 
VAL HG23 H N N 435 
VAL HXT  H N N 436 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BEM O3  C3   sing N N 70  
BEM O2  C2   sing N N 71  
BEM C3  C4   sing N N 72  
BEM C3  C2   sing N N 73  
BEM O4  C4   sing N N 74  
BEM C4  C5   sing N N 75  
BEM C2  C1   sing N N 76  
BEM O6A C6   doub N N 77  
BEM C5  O5   sing N N 78  
BEM C5  C6   sing N N 79  
BEM C1  O5   sing N N 80  
BEM C1  O1   sing N N 81  
BEM C6  O6B  sing N N 82  
BEM C1  H1   sing N N 83  
BEM C2  H2   sing N N 84  
BEM O2  HO2  sing N N 85  
BEM C3  H3   sing N N 86  
BEM O3  HO3  sing N N 87  
BEM C4  H4   sing N N 88  
BEM O4  HO4  sing N N 89  
BEM C5  H5   sing N N 90  
BEM O1  HO1  sing N N 91  
BEM O6B HO6B sing N N 92  
CYS N   CA   sing N N 93  
CYS N   H    sing N N 94  
CYS N   H2   sing N N 95  
CYS CA  C    sing N N 96  
CYS CA  CB   sing N N 97  
CYS CA  HA   sing N N 98  
CYS C   O    doub N N 99  
CYS C   OXT  sing N N 100 
CYS CB  SG   sing N N 101 
CYS CB  HB2  sing N N 102 
CYS CB  HB3  sing N N 103 
CYS SG  HG   sing N N 104 
CYS OXT HXT  sing N N 105 
GLN N   CA   sing N N 106 
GLN N   H    sing N N 107 
GLN N   H2   sing N N 108 
GLN CA  C    sing N N 109 
GLN CA  CB   sing N N 110 
GLN CA  HA   sing N N 111 
GLN C   O    doub N N 112 
GLN C   OXT  sing N N 113 
GLN CB  CG   sing N N 114 
GLN CB  HB2  sing N N 115 
GLN CB  HB3  sing N N 116 
GLN CG  CD   sing N N 117 
GLN CG  HG2  sing N N 118 
GLN CG  HG3  sing N N 119 
GLN CD  OE1  doub N N 120 
GLN CD  NE2  sing N N 121 
GLN NE2 HE21 sing N N 122 
GLN NE2 HE22 sing N N 123 
GLN OXT HXT  sing N N 124 
GLU N   CA   sing N N 125 
GLU N   H    sing N N 126 
GLU N   H2   sing N N 127 
GLU CA  C    sing N N 128 
GLU CA  CB   sing N N 129 
GLU CA  HA   sing N N 130 
GLU C   O    doub N N 131 
GLU C   OXT  sing N N 132 
GLU CB  CG   sing N N 133 
GLU CB  HB2  sing N N 134 
GLU CB  HB3  sing N N 135 
GLU CG  CD   sing N N 136 
GLU CG  HG2  sing N N 137 
GLU CG  HG3  sing N N 138 
GLU CD  OE1  doub N N 139 
GLU CD  OE2  sing N N 140 
GLU OE2 HE2  sing N N 141 
GLU OXT HXT  sing N N 142 
GLY N   CA   sing N N 143 
GLY N   H    sing N N 144 
GLY N   H2   sing N N 145 
GLY CA  C    sing N N 146 
GLY CA  HA2  sing N N 147 
GLY CA  HA3  sing N N 148 
GLY C   O    doub N N 149 
GLY C   OXT  sing N N 150 
GLY OXT HXT  sing N N 151 
HIS N   CA   sing N N 152 
HIS N   H    sing N N 153 
HIS N   H2   sing N N 154 
HIS CA  C    sing N N 155 
HIS CA  CB   sing N N 156 
HIS CA  HA   sing N N 157 
HIS C   O    doub N N 158 
HIS C   OXT  sing N N 159 
HIS CB  CG   sing N N 160 
HIS CB  HB2  sing N N 161 
HIS CB  HB3  sing N N 162 
HIS CG  ND1  sing Y N 163 
HIS CG  CD2  doub Y N 164 
HIS ND1 CE1  doub Y N 165 
HIS ND1 HD1  sing N N 166 
HIS CD2 NE2  sing Y N 167 
HIS CD2 HD2  sing N N 168 
HIS CE1 NE2  sing Y N 169 
HIS CE1 HE1  sing N N 170 
HIS NE2 HE2  sing N N 171 
HIS OXT HXT  sing N N 172 
HOH O   H1   sing N N 173 
HOH O   H2   sing N N 174 
ILE N   CA   sing N N 175 
ILE N   H    sing N N 176 
ILE N   H2   sing N N 177 
ILE CA  C    sing N N 178 
ILE CA  CB   sing N N 179 
ILE CA  HA   sing N N 180 
ILE C   O    doub N N 181 
ILE C   OXT  sing N N 182 
ILE CB  CG1  sing N N 183 
ILE CB  CG2  sing N N 184 
ILE CB  HB   sing N N 185 
ILE CG1 CD1  sing N N 186 
ILE CG1 HG12 sing N N 187 
ILE CG1 HG13 sing N N 188 
ILE CG2 HG21 sing N N 189 
ILE CG2 HG22 sing N N 190 
ILE CG2 HG23 sing N N 191 
ILE CD1 HD11 sing N N 192 
ILE CD1 HD12 sing N N 193 
ILE CD1 HD13 sing N N 194 
ILE OXT HXT  sing N N 195 
LEU N   CA   sing N N 196 
LEU N   H    sing N N 197 
LEU N   H2   sing N N 198 
LEU CA  C    sing N N 199 
LEU CA  CB   sing N N 200 
LEU CA  HA   sing N N 201 
LEU C   O    doub N N 202 
LEU C   OXT  sing N N 203 
LEU CB  CG   sing N N 204 
LEU CB  HB2  sing N N 205 
LEU CB  HB3  sing N N 206 
LEU CG  CD1  sing N N 207 
LEU CG  CD2  sing N N 208 
LEU CG  HG   sing N N 209 
LEU CD1 HD11 sing N N 210 
LEU CD1 HD12 sing N N 211 
LEU CD1 HD13 sing N N 212 
LEU CD2 HD21 sing N N 213 
LEU CD2 HD22 sing N N 214 
LEU CD2 HD23 sing N N 215 
LEU OXT HXT  sing N N 216 
LGU C1  C2   sing N N 217 
LGU C1  O5   sing N N 218 
LGU C1  O1   sing N N 219 
LGU C1  H1   sing N N 220 
LGU C2  O2   sing N N 221 
LGU C2  C3   sing N N 222 
LGU C2  H2   sing N N 223 
LGU O2  HO2  sing N N 224 
LGU C3  O3   sing N N 225 
LGU C3  C4   sing N N 226 
LGU C3  H3   sing N N 227 
LGU O3  HO3  sing N N 228 
LGU C4  O4   sing N N 229 
LGU C4  C5   sing N N 230 
LGU C4  H4   sing N N 231 
LGU O4  HO4  sing N N 232 
LGU C5  O5   sing N N 233 
LGU C5  C6   sing N N 234 
LGU C5  H5   sing N N 235 
LGU C6  O6B  sing N N 236 
LGU C6  O6A  doub N N 237 
LGU O6B HO6B sing N N 238 
LGU O1  HO1  sing N N 239 
LYS N   CA   sing N N 240 
LYS N   H    sing N N 241 
LYS N   H2   sing N N 242 
LYS CA  C    sing N N 243 
LYS CA  CB   sing N N 244 
LYS CA  HA   sing N N 245 
LYS C   O    doub N N 246 
LYS C   OXT  sing N N 247 
LYS CB  CG   sing N N 248 
LYS CB  HB2  sing N N 249 
LYS CB  HB3  sing N N 250 
LYS CG  CD   sing N N 251 
LYS CG  HG2  sing N N 252 
LYS CG  HG3  sing N N 253 
LYS CD  CE   sing N N 254 
LYS CD  HD2  sing N N 255 
LYS CD  HD3  sing N N 256 
LYS CE  NZ   sing N N 257 
LYS CE  HE2  sing N N 258 
LYS CE  HE3  sing N N 259 
LYS NZ  HZ1  sing N N 260 
LYS NZ  HZ2  sing N N 261 
LYS NZ  HZ3  sing N N 262 
LYS OXT HXT  sing N N 263 
MET N   CA   sing N N 264 
MET N   H    sing N N 265 
MET N   H2   sing N N 266 
MET CA  C    sing N N 267 
MET CA  CB   sing N N 268 
MET CA  HA   sing N N 269 
MET C   O    doub N N 270 
MET C   OXT  sing N N 271 
MET CB  CG   sing N N 272 
MET CB  HB2  sing N N 273 
MET CB  HB3  sing N N 274 
MET CG  SD   sing N N 275 
MET CG  HG2  sing N N 276 
MET CG  HG3  sing N N 277 
MET SD  CE   sing N N 278 
MET CE  HE1  sing N N 279 
MET CE  HE2  sing N N 280 
MET CE  HE3  sing N N 281 
MET OXT HXT  sing N N 282 
PHE N   CA   sing N N 283 
PHE N   H    sing N N 284 
PHE N   H2   sing N N 285 
PHE CA  C    sing N N 286 
PHE CA  CB   sing N N 287 
PHE CA  HA   sing N N 288 
PHE C   O    doub N N 289 
PHE C   OXT  sing N N 290 
PHE CB  CG   sing N N 291 
PHE CB  HB2  sing N N 292 
PHE CB  HB3  sing N N 293 
PHE CG  CD1  doub Y N 294 
PHE CG  CD2  sing Y N 295 
PHE CD1 CE1  sing Y N 296 
PHE CD1 HD1  sing N N 297 
PHE CD2 CE2  doub Y N 298 
PHE CD2 HD2  sing N N 299 
PHE CE1 CZ   doub Y N 300 
PHE CE1 HE1  sing N N 301 
PHE CE2 CZ   sing Y N 302 
PHE CE2 HE2  sing N N 303 
PHE CZ  HZ   sing N N 304 
PHE OXT HXT  sing N N 305 
PRO N   CA   sing N N 306 
PRO N   CD   sing N N 307 
PRO N   H    sing N N 308 
PRO CA  C    sing N N 309 
PRO CA  CB   sing N N 310 
PRO CA  HA   sing N N 311 
PRO C   O    doub N N 312 
PRO C   OXT  sing N N 313 
PRO CB  CG   sing N N 314 
PRO CB  HB2  sing N N 315 
PRO CB  HB3  sing N N 316 
PRO CG  CD   sing N N 317 
PRO CG  HG2  sing N N 318 
PRO CG  HG3  sing N N 319 
PRO CD  HD2  sing N N 320 
PRO CD  HD3  sing N N 321 
PRO OXT HXT  sing N N 322 
SER N   CA   sing N N 323 
SER N   H    sing N N 324 
SER N   H2   sing N N 325 
SER CA  C    sing N N 326 
SER CA  CB   sing N N 327 
SER CA  HA   sing N N 328 
SER C   O    doub N N 329 
SER C   OXT  sing N N 330 
SER CB  OG   sing N N 331 
SER CB  HB2  sing N N 332 
SER CB  HB3  sing N N 333 
SER OG  HG   sing N N 334 
SER OXT HXT  sing N N 335 
THR N   CA   sing N N 336 
THR N   H    sing N N 337 
THR N   H2   sing N N 338 
THR CA  C    sing N N 339 
THR CA  CB   sing N N 340 
THR CA  HA   sing N N 341 
THR C   O    doub N N 342 
THR C   OXT  sing N N 343 
THR CB  OG1  sing N N 344 
THR CB  CG2  sing N N 345 
THR CB  HB   sing N N 346 
THR OG1 HG1  sing N N 347 
THR CG2 HG21 sing N N 348 
THR CG2 HG22 sing N N 349 
THR CG2 HG23 sing N N 350 
THR OXT HXT  sing N N 351 
TRP N   CA   sing N N 352 
TRP N   H    sing N N 353 
TRP N   H2   sing N N 354 
TRP CA  C    sing N N 355 
TRP CA  CB   sing N N 356 
TRP CA  HA   sing N N 357 
TRP C   O    doub N N 358 
TRP C   OXT  sing N N 359 
TRP CB  CG   sing N N 360 
TRP CB  HB2  sing N N 361 
TRP CB  HB3  sing N N 362 
TRP CG  CD1  doub Y N 363 
TRP CG  CD2  sing Y N 364 
TRP CD1 NE1  sing Y N 365 
TRP CD1 HD1  sing N N 366 
TRP CD2 CE2  doub Y N 367 
TRP CD2 CE3  sing Y N 368 
TRP NE1 CE2  sing Y N 369 
TRP NE1 HE1  sing N N 370 
TRP CE2 CZ2  sing Y N 371 
TRP CE3 CZ3  doub Y N 372 
TRP CE3 HE3  sing N N 373 
TRP CZ2 CH2  doub Y N 374 
TRP CZ2 HZ2  sing N N 375 
TRP CZ3 CH2  sing Y N 376 
TRP CZ3 HZ3  sing N N 377 
TRP CH2 HH2  sing N N 378 
TRP OXT HXT  sing N N 379 
TYR N   CA   sing N N 380 
TYR N   H    sing N N 381 
TYR N   H2   sing N N 382 
TYR CA  C    sing N N 383 
TYR CA  CB   sing N N 384 
TYR CA  HA   sing N N 385 
TYR C   O    doub N N 386 
TYR C   OXT  sing N N 387 
TYR CB  CG   sing N N 388 
TYR CB  HB2  sing N N 389 
TYR CB  HB3  sing N N 390 
TYR CG  CD1  doub Y N 391 
TYR CG  CD2  sing Y N 392 
TYR CD1 CE1  sing Y N 393 
TYR CD1 HD1  sing N N 394 
TYR CD2 CE2  doub Y N 395 
TYR CD2 HD2  sing N N 396 
TYR CE1 CZ   doub Y N 397 
TYR CE1 HE1  sing N N 398 
TYR CE2 CZ   sing Y N 399 
TYR CE2 HE2  sing N N 400 
TYR CZ  OH   sing N N 401 
TYR OH  HH   sing N N 402 
TYR OXT HXT  sing N N 403 
VAL N   CA   sing N N 404 
VAL N   H    sing N N 405 
VAL N   H2   sing N N 406 
VAL CA  C    sing N N 407 
VAL CA  CB   sing N N 408 
VAL CA  HA   sing N N 409 
VAL C   O    doub N N 410 
VAL C   OXT  sing N N 411 
VAL CB  CG1  sing N N 412 
VAL CB  CG2  sing N N 413 
VAL CB  HB   sing N N 414 
VAL CG1 HG11 sing N N 415 
VAL CG1 HG12 sing N N 416 
VAL CG1 HG13 sing N N 417 
VAL CG2 HG21 sing N N 418 
VAL CG2 HG22 sing N N 419 
VAL CG2 HG23 sing N N 420 
VAL OXT HXT  sing N N 421 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 BEM 1 n 
2 LGU 2 n 
2 BEM 3 n 
2 BEM 4 n 
2 BEM 5 n 
2 BEM 6 n 
3 BEM 1 n 
3 BEM 2 n 
3 BEM 3 n 
3 BEM 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8C3X 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8QIZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.023425 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.010744 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014418 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.025633 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . GLU A 1 1   ? 16.81011  6.34357   34.83691  1.000 45.25327  ? 15  GLU A N    1 
ATOM   2    C CA   . GLU A 1 1   ? 17.73906  5.27617   35.19477  1.000 44.67003  ? 15  GLU A CA   1 
ATOM   3    C C    . GLU A 1 1   ? 18.62271  4.88922   34.01205  1.000 37.85424  ? 15  GLU A C    1 
ATOM   4    O O    . GLU A 1 1   ? 18.28490  5.15667   32.86001  1.000 37.76507  ? 15  GLU A O    1 
ATOM   5    C CB   . GLU A 1 1   ? 16.98120  4.04430   35.70472  1.000 50.28313  ? 15  GLU A CB   1 
ATOM   6    C CG   . GLU A 1 1   ? 16.41219  3.13031   34.61031  1.000 54.95594  ? 15  GLU A CG   1 
ATOM   7    C CD   . GLU A 1 1   ? 15.01112  3.52434   34.15872  1.000 58.37499  ? 15  GLU A CD   1 
ATOM   8    O OE1  . GLU A 1 1   ? 14.88571  4.41658   33.29103  1.000 59.32151  ? 15  GLU A OE1  1 
ATOM   9    O OE2  . GLU A 1 1   ? 14.03432  2.93668   34.67556  1.000 59.69743  ? 15  GLU A OE2  1 
ATOM   10   N N    . PHE A 1 2   ? 19.74745  4.24393   34.30764  1.000 31.05930  ? 16  PHE A N    1 
ATOM   11   C CA   . PHE A 1 2   ? 20.68552  3.84058   33.26851  1.000 24.79683  ? 16  PHE A CA   1 
ATOM   12   C C    . PHE A 1 2   ? 20.04822  2.81145   32.34299  1.000 21.47768  ? 16  PHE A C    1 
ATOM   13   O O    . PHE A 1 2   ? 19.46547  1.82153   32.79640  1.000 22.29637  ? 16  PHE A O    1 
ATOM   14   C CB   . PHE A 1 2   ? 21.94221  3.25580   33.91793  1.000 24.25727  ? 16  PHE A CB   1 
ATOM   15   C CG   . PHE A 1 2   ? 23.02758  2.90544   32.94050  1.000 24.75954  ? 16  PHE A CG   1 
ATOM   16   C CD1  . PHE A 1 2   ? 23.08519  1.64400   32.37148  1.000 25.07636  ? 16  PHE A CD1  1 
ATOM   17   C CD2  . PHE A 1 2   ? 24.00192  3.83256   32.60304  1.000 25.72040  ? 16  PHE A CD2  1 
ATOM   18   C CE1  . PHE A 1 2   ? 24.09074  1.31276   31.47527  1.000 25.34653  ? 16  PHE A CE1  1 
ATOM   19   C CE2  . PHE A 1 2   ? 25.00899  3.51102   31.70247  1.000 26.46677  ? 16  PHE A CE2  1 
ATOM   20   C CZ   . PHE A 1 2   ? 25.05235  2.24756   31.13520  1.000 26.29345  ? 16  PHE A CZ   1 
ATOM   21   N N    . LEU A 1 3   ? 20.16642  3.04863   31.04265  1.000 18.36500  ? 17  LEU A N    1 
ATOM   22   C CA   . LEU A 1 3   ? 19.65098  2.13418   30.03962  1.000 17.44922  ? 17  LEU A CA   1 
ATOM   23   C C    . LEU A 1 3   ? 20.79943  1.31403   29.48532  1.000 15.67122  ? 17  LEU A C    1 
ATOM   24   O O    . LEU A 1 3   ? 21.78714  1.86545   28.99167  1.000 16.98706  ? 17  LEU A O    1 
ATOM   25   C CB   . LEU A 1 3   ? 18.98751  2.90643   28.90383  1.000 18.52245  ? 17  LEU A CB   1 
ATOM   26   C CG   . LEU A 1 3   ? 17.62666  3.51595   29.21707  1.000 19.26882  ? 17  LEU A CG   1 
ATOM   27   C CD1  . LEU A 1 3   ? 17.00956  3.99347   27.93498  1.000 20.53024  ? 17  LEU A CD1  1 
ATOM   28   C CD2  . LEU A 1 3   ? 16.71841  2.48989   29.87544  1.000 20.57334  ? 17  LEU A CD2  1 
ATOM   29   N N    . THR A 1 4   ? 20.64637  -0.00123  29.54358  1.000 14.60546  ? 18  THR A N    1 
ATOM   30   C CA   . THR A 1 4   ? 21.66661  -0.93765  29.10129  1.000 14.37801  ? 18  THR A CA   1 
ATOM   31   C C    . THR A 1 4   ? 21.39702  -1.32970  27.65518  1.000 12.90827  ? 18  THR A C    1 
ATOM   32   O O    . THR A 1 4   ? 20.25700  -1.61596  27.28704  1.000 13.31433  ? 18  THR A O    1 
ATOM   33   C CB   . THR A 1 4   ? 21.62651  -2.16832  30.00571  1.000 16.21865  ? 18  THR A CB   1 
ATOM   34   O OG1  . THR A 1 4   ? 21.88342  -1.76365  31.35543  1.000 18.26006  ? 18  THR A OG1  1 
ATOM   35   C CG2  . THR A 1 4   ? 22.65519  -3.19305  29.58344  1.000 17.11714  ? 18  THR A CG2  1 
ATOM   36   H H    . THR A 1 4   ? 19.93901  -0.38684  29.84447  1.000 17.52144  ? 18  THR A H    1 
ATOM   37   H HA   . THR A 1 4   ? 22.54941  -0.53787  29.14315  1.000 17.24851  ? 18  THR A HA   1 
ATOM   38   H HB   . THR A 1 4   ? 20.75312  -2.58576  29.94380  1.000 19.45727  ? 18  THR A HB   1 
ATOM   39   H HG1  . THR A 1 4   ? 22.64810  -1.42060  31.41190  1.000 21.90696  ? 18  THR A HG1  1 
ATOM   40   H HG21 . THR A 1 4   ? 22.78004  -3.84771  30.28823  1.000 20.53546  ? 18  THR A HG21 1 
ATOM   41   H HG22 . THR A 1 4   ? 22.35936  -3.64837  28.77966  1.000 20.53546  ? 18  THR A HG22 1 
ATOM   42   H HG23 . THR A 1 4   ? 23.50325  -2.75753  29.40450  1.000 20.53546  ? 18  THR A HG23 1 
ATOM   43   N N    . ALA A 1 5   ? 22.44603  -1.33265  26.84407  1.000 12.91210  ? 19  ALA A N    1 
ATOM   44   C CA   . ALA A 1 5   ? 22.31764  -1.64262  25.43238  1.000 13.45640  ? 19  ALA A CA   1 
ATOM   45   C C    . ALA A 1 5   ? 22.11858  -3.12985  25.20319  1.000 12.48501  ? 19  ALA A C    1 
ATOM   46   O O    . ALA A 1 5   ? 22.70526  -3.97841  25.88397  1.000 13.10514  ? 19  ALA A O    1 
ATOM   47   C CB   . ALA A 1 5   ? 23.56860  -1.20264  24.68345  1.000 13.60997  ? 19  ALA A CB   1 
ATOM   48   H H    . ALA A 1 5   ? 23.25066  -1.15636  27.09124  1.000 15.48941  ? 19  ALA A H    1 
ATOM   49   H HA   . ALA A 1 5   ? 21.54365  -1.17175  25.08580  1.000 16.14257  ? 19  ALA A HA   1 
ATOM   50   H HB1  . ALA A 1 5   ? 23.66263  -0.24054  24.76354  1.000 16.32685  ? 19  ALA A HB1  1 
ATOM   51   H HB2  . ALA A 1 5   ? 24.34047  -1.64385  25.07134  1.000 16.32685  ? 19  ALA A HB2  1 
ATOM   52   H HB3  . ALA A 1 5   ? 23.48092  -1.44983  23.74959  1.000 16.32685  ? 19  ALA A HB3  1 
ATOM   53   N N    . VAL A 1 6   ? 21.32048  -3.44247  24.19329  1.000 11.86774  ? 20  VAL A N    1 
ATOM   54   C CA   . VAL A 1 6   ? 21.09940  -4.82718  23.81548  1.000 12.30400  ? 20  VAL A CA   1 
ATOM   55   C C    . VAL A 1 6   ? 22.41329  -5.51615  23.46569  1.000 12.14093  ? 20  VAL A C    1 
ATOM   56   O O    . VAL A 1 6   ? 22.59667  -6.69984  23.76270  1.000 12.73681  ? 20  VAL A O    1 
ATOM   57   C CB   . VAL A 1 6   ? 20.06641  -4.89288  22.67343  1.000 11.76733  ? 20  VAL A CB   1 
ATOM   58   C CG1  . VAL A 1 6   ? 19.93781  -6.31339  22.13418  1.000 13.09738  ? 20  VAL A CG1  1 
ATOM   59   C CG2  . VAL A 1 6   ? 18.71327  -4.38066  23.16648  1.000 12.24448  ? 20  VAL A CG2  1 
ATOM   60   H H    . VAL A 1 6   ? 20.89503  -2.87182  23.71064  1.000 14.23618  ? 20  VAL A H    1 
ATOM   61   H HA   . VAL A 1 6   ? 20.73335  -5.30741  24.57461  1.000 14.75969  ? 20  VAL A HA   1 
ATOM   62   H HB   . VAL A 1 6   ? 20.36710  -4.32829  21.94424  1.000 14.11569  ? 20  VAL A HB   1 
ATOM   63   H HG11 . VAL A 1 6   ? 19.13871  -6.37252  21.58751  1.000 15.71174  ? 20  VAL A HG11 1 
ATOM   64   H HG12 . VAL A 1 6   ? 20.72033  -6.52031  21.59963  1.000 15.71174  ? 20  VAL A HG12 1 
ATOM   65   H HG13 . VAL A 1 6   ? 19.87448  -6.92992  22.88036  0.395 15.71174  ? 20  VAL A HG13 1 
ATOM   66   H HG21 . VAL A 1 6   ? 18.10644  -4.31563  22.41254  1.000 14.68827  ? 20  VAL A HG21 1 
ATOM   67   H HG22 . VAL A 1 6   ? 18.36038  -5.00196  23.82249  1.000 14.68827  ? 20  VAL A HG22 1 
ATOM   68   H HG23 . VAL A 1 6   ? 18.83431  -3.50692  23.56999  1.000 14.68827  ? 20  VAL A HG23 1 
ATOM   69   N N    . SER A 1 7   ? 23.33682  -4.80338  22.82268  1.000 12.37907  ? 21  SER A N    1 
ATOM   70   C CA   . SER A 1 7   ? 24.60846  -5.40627  22.42487  1.000 13.77988  ? 21  SER A CA   1 
ATOM   71   C C    . SER A 1 7   ? 25.57191  -5.64278  23.58621  1.000 14.18505  ? 21  SER A C    1 
ATOM   72   O O    . SER A 1 7   ? 26.68350  -6.12361  23.33873  1.000 15.71102  ? 21  SER A O    1 
ATOM   73   C CB   . SER A 1 7   ? 25.28386  -4.54309  21.36909  1.000 14.26438  ? 21  SER A CB   1 
ATOM   74   O OG   . SER A 1 7   ? 25.55964  -3.25837  21.88275  1.000 15.63642  ? 21  SER A OG   1 
ATOM   75   H H    . SER A 1 7   ? 23.25226  -3.97527  22.60662  0.807 14.84977  ? 21  SER A H    1 
ATOM   76   H HA   . SER A 1 7   ? 24.41565  -6.27299  22.03431  1.000 16.53075  ? 21  SER A HA   1 
ATOM   77   H HB2  . SER A 1 7   ? 26.11633  -4.96292  21.10145  0.874 17.11215  ? 21  SER A HB2  1 
ATOM   78   H HB3  . SER A 1 7   ? 24.69387  -4.45859  20.60380  1.000 17.11215  ? 21  SER A HB3  1 
ATOM   79   H HG   . SER A 1 7   ? 24.84915  -2.89544  22.14557  0.647 18.75860  ? 21  SER A HG   1 
ATOM   80   N N    . SER A 1 8   ? 25.19248  -5.31320  24.81981  1.000 14.36355  ? 22  SER A N    1 
ATOM   81   C CA   . SER A 1 8   ? 26.08051  -5.50096  25.96238  1.000 15.76173  ? 22  SER A CA   1 
ATOM   82   C C    . SER A 1 8   ? 26.19617  -6.95728  26.38633  1.000 16.72852  ? 22  SER A C    1 
ATOM   83   O O    . SER A 1 8   ? 27.06247  -7.26706  27.21936  1.000 18.26073  ? 22  SER A O    1 
ATOM   84   C CB   . SER A 1 8   ? 25.59281  -4.65806  27.14211  1.000 16.58709  ? 22  SER A CB   1 
ATOM   85   O OG   . SER A 1 8   ? 24.38502  -5.16669  27.66127  1.000 17.62733  ? 22  SER A OG   1 
ATOM   86   H H    . SER A 1 8   ? 24.42573  -4.97920  25.02018  1.000 17.23116  ? 22  SER A H    1 
ATOM   87   H HA   . SER A 1 8   ? 26.96870  -5.19314  25.72309  0.393 18.90897  ? 22  SER A HA   1 
ATOM   88   H HB2  . SER A 1 8   ? 26.26662  -4.67269  27.83973  0.036 19.89941  ? 22  SER A HB2  1 
ATOM   89   H HB3  . SER A 1 8   ? 25.44750  -3.74775  26.84026  1.000 19.89941  ? 22  SER A HB3  1 
ATOM   90   H HG   . SER A 1 8   ? 23.77457  -5.09810  27.08835  1.000 21.14769  ? 22  SER A HG   1 
ATOM   91   N N    . ILE A 1 9   ? 25.35632  -7.84373  25.84828  1.000 15.09874  ? 23  ILE A N    1 
ATOM   92   C CA   . ILE A 1 9   ? 25.45360  -9.27488  26.07804  1.000 15.29039  ? 23  ILE A CA   1 
ATOM   93   C C    . ILE A 1 9   ? 25.66524  -9.96444  24.73382  1.000 15.47641  ? 23  ILE A C    1 
ATOM   94   O O    . ILE A 1 9   ? 25.59440  -9.34158  23.67881  1.000 16.06733  ? 23  ILE A O    1 
ATOM   95   C CB   . ILE A 1 9   ? 24.23854  -9.83930  26.84051  1.000 15.35322  ? 23  ILE A CB   1 
ATOM   96   C CG1  . ILE A 1 9   ? 22.94924  -9.67502  26.04215  1.000 15.05639  ? 23  ILE A CG1  1 
ATOM   97   C CG2  . ILE A 1 9   ? 24.14004  -9.16778  28.21416  1.000 16.46469  ? 23  ILE A CG2  1 
ATOM   98   C CD1  . ILE A 1 9   ? 21.77288  -10.37101 26.68205  1.000 16.01412  ? 23  ILE A CD1  1 
ATOM   99   H H    . ILE A 1 9   ? 24.70377  -7.62766  25.33147  1.000 18.11338  ? 23  ILE A H    1 
ATOM   100  H HA   . ILE A 1 9   ? 26.23388  -9.46028  26.62365  1.000 18.34337  ? 23  ILE A HA   1 
ATOM   101  H HB   . ILE A 1 9   ? 24.36746  -10.79259 26.96513  0.894 18.41876  ? 23  ILE A HB   1 
ATOM   102  H HG12 . ILE A 1 9   ? 22.73847  -8.73067  25.97380  0.977 18.06256  ? 23  ILE A HG12 1 
ATOM   103  H HG13 . ILE A 1 9   ? 23.07580  -10.05159 25.15723  1.000 18.06256  ? 23  ILE A HG13 1 
ATOM   104  H HG21 . ILE A 1 9   ? 24.99894  -9.23348  28.66011  0.808 19.75252  ? 23  ILE A HG21 1 
ATOM   105  H HG22 . ILE A 1 9   ? 23.90042  -8.23561  28.09352  0.900 19.75252  ? 23  ILE A HG22 1 
ATOM   106  H HG23 . ILE A 1 9   ? 23.45986  -9.61901  28.73822  1.000 19.75252  ? 23  ILE A HG23 1 
ATOM   107  H HD11 . ILE A 1 9   ? 21.01153  -10.31955 26.08322  1.000 19.21184  ? 23  ILE A HD11 1 
ATOM   108  H HD12 . ILE A 1 9   ? 22.00458  -11.29899 26.84351  1.000 19.21184  ? 23  ILE A HD12 1 
ATOM   109  H HD13 . ILE A 1 9   ? 21.56406  -9.93141  27.52112  1.000 19.21184  ? 23  ILE A HD13 1 
ATOM   110  N N    . ASP A 1 10  ? 25.92884  -11.26969 24.77269  1.000 15.11867  ? 24  ASP A N    1 
ATOM   111  C CA   . ASP A 1 10  ? 26.20521  -11.98245 23.53024  1.000 15.79432  ? 24  ASP A CA   1 
ATOM   112  C C    . ASP A 1 10  ? 24.95350  -12.46948 22.81327  1.000 14.59056  ? 24  ASP A C    1 
ATOM   113  O O    . ASP A 1 10  ? 25.01965  -12.74378 21.61431  1.000 15.57060  ? 24  ASP A O    1 
ATOM   114  C CB   . ASP A 1 10  ? 27.17526  -13.15879 23.74961  1.000 18.62786  ? 24  ASP A CB   1 
ATOM   115  C CG   . ASP A 1 10  ? 26.62275  -14.25155 24.63767  1.000 22.93719  ? 24  ASP A CG   1 
ATOM   116  O OD1  . ASP A 1 10  ? 25.62889  -14.02767 25.35529  1.000 24.40106  ? 24  ASP A OD1  1 
ATOM   117  O OD2  . ASP A 1 10  ? 27.23165  -15.35117 24.64112  1.000 26.78802  ? 24  ASP A OD2  1 
ATOM   118  H H    . ASP A 1 10  ? 25.95255  -11.74973 25.48585  0.838 18.13729  ? 24  ASP A H    1 
ATOM   119  H HA   . ASP A 1 10  ? 26.65710  -11.36269 22.93644  1.000 18.94807  ? 24  ASP A HA   1 
ATOM   120  H HB2  . ASP A 1 10  ? 27.38407  -13.55516 22.88927  1.000 22.34832  ? 24  ASP A HB2  1 
ATOM   121  H HB3  . ASP A 1 10  ? 27.98459  -12.82207 24.16495  1.000 22.34832  ? 24  ASP A HB3  1 
ATOM   122  N N    . THR A 1 11  ? 23.82416  -12.54774 23.51210  1.000 13.76868  ? 25  THR A N    1 
ATOM   123  C CA   . THR A 1 11  ? 22.66278  -13.29632 23.03105  1.000 13.73253  ? 25  THR A CA   1 
ATOM   124  C C    . THR A 1 11  ? 22.15982  -12.82009 21.68022  1.000 13.07670  ? 25  THR A C    1 
ATOM   125  O O    . THR A 1 11  ? 21.76805  -13.63877 20.84762  1.000 14.33832  ? 25  THR A O    1 
ATOM   126  C CB   . THR A 1 11  ? 21.56722  -13.18649 24.07723  1.000 14.51028  ? 25  THR A CB   1 
ATOM   127  O OG1  . THR A 1 11  ? 22.10020  -13.71435 25.28816  1.000 15.16178  ? 25  THR A OG1  1 
ATOM   128  C CG2  . THR A 1 11  ? 20.29293  -13.93804 23.67130  1.000 15.21416  ? 25  THR A CG2  1 
ATOM   129  H H    . THR A 1 11  ? 23.70028  -12.17340 24.27638  1.000 16.51731  ? 25  THR A H    1 
ATOM   130  H HA   . THR A 1 11  ? 22.91758  -14.22415 22.90810  1.000 16.47393  ? 25  THR A HA   1 
ATOM   131  H HB   . THR A 1 11  ? 21.29343  -12.26269 24.18919  1.000 17.40722  ? 25  THR A HB   1 
ATOM   132  H HG1  . THR A 1 11  ? 21.49979  -13.75082 25.87449  1.000 18.18903  ? 25  THR A HG1  1 
ATOM   133  H HG21 . THR A 1 11  ? 19.64986  -13.91696 24.39719  1.000 18.25188  ? 25  THR A HG21 1 
ATOM   134  H HG22 . THR A 1 11  ? 19.89796  -13.52284 22.88867  1.000 18.25188  ? 25  THR A HG22 1 
ATOM   135  H HG23 . THR A 1 11  ? 20.50424  -14.86192 23.46468  1.000 18.25188  ? 25  THR A HG23 1 
ATOM   136  N N    . PHE A 1 12  ? 22.12646  -11.51593 21.45090  1.000 12.25154  ? 26  PHE A N    1 
ATOM   137  C CA   . PHE A 1 12  ? 21.50885  -10.97880 20.24455  1.000 12.33009  ? 26  PHE A CA   1 
ATOM   138  C C    . PHE A 1 12  ? 22.51951  -10.53556 19.19874  1.000 12.59182  ? 26  PHE A C    1 
ATOM   139  O O    . PHE A 1 12  ? 22.11908  -10.03650 18.14680  1.000 12.80405  ? 26  PHE A O    1 
ATOM   140  C CB   . PHE A 1 12  ? 20.55846  -9.82749  20.60745  1.000 11.95053  ? 26  PHE A CB   1 
ATOM   141  C CG   . PHE A 1 12  ? 19.54019  -10.21914 21.63237  1.000 11.70230  ? 26  PHE A CG   1 
ATOM   142  C CD1  . PHE A 1 12  ? 18.42036  -10.95629 21.27214  1.000 12.31871  ? 26  PHE A CD1  1 
ATOM   143  C CD2  . PHE A 1 12  ? 19.72375  -9.90432  22.96901  1.000 12.38796  ? 26  PHE A CD2  1 
ATOM   144  C CE1  . PHE A 1 12  ? 17.50130  -11.34852 22.22165  1.000 12.86493  ? 26  PHE A CE1  1 
ATOM   145  C CE2  . PHE A 1 12  ? 18.81041  -10.29332 23.92100  1.000 12.45659  ? 26  PHE A CE2  1 
ATOM   146  C CZ   . PHE A 1 12  ? 17.69828  -11.01469 23.55463  1.000 12.94941  ? 26  PHE A CZ   1 
ATOM   147  H H    . PHE A 1 12  ? 22.45437  -10.92079 21.97804  1.000 14.69675  ? 26  PHE A H    1 
ATOM   148  H HA   . PHE A 1 12  ? 20.97196  -11.67422 19.83340  1.000 14.79100  ? 26  PHE A HA   1 
ATOM   149  H HB2  . PHE A 1 12  ? 21.07746  -9.09059  20.96595  1.000 14.33552  ? 26  PHE A HB2  1 
ATOM   150  H HB3  . PHE A 1 12  ? 20.08692  -9.54352  19.80875  1.000 14.33552  ? 26  PHE A HB3  1 
ATOM   151  H HD1  . PHE A 1 12  ? 18.28888  -11.18785 20.38108  1.000 14.77735  ? 26  PHE A HD1  1 
ATOM   152  H HD2  . PHE A 1 12  ? 20.47629  -9.42242  23.22659  1.000 14.86044  ? 26  PHE A HD2  1 
ATOM   153  H HE1  . PHE A 1 12  ? 16.75047  -11.83602 21.96966  1.000 15.43281  ? 26  PHE A HE1  1 
ATOM   154  H HE2  . PHE A 1 12  ? 18.94502  -10.06833 24.81328  0.768 14.94279  ? 26  PHE A HE2  1 
ATOM   155  H HZ   . PHE A 1 12  ? 17.08025  -11.27797 24.19776  1.000 15.53418  ? 26  PHE A HZ   1 
ATOM   156  N N    . LEU A 1 13  ? 23.81585  -10.71807 19.43948  1.000 12.81421  ? 27  LEU A N    1 
ATOM   157  C CA   . LEU A 1 13  ? 24.78303  -10.25747 18.45145  1.000 13.54989  ? 27  LEU A CA   1 
ATOM   158  C C    . LEU A 1 13  ? 24.58942  -10.89676 17.08423  1.000 12.67802  ? 27  LEU A C    1 
ATOM   159  O O    . LEU A 1 13  ? 24.74117  -10.18797 16.07488  1.000 13.54663  ? 27  LEU A O    1 
ATOM   160  C CB   . LEU A 1 13  ? 26.21175  -10.45483 18.95877  1.000 15.67134  ? 27  LEU A CB   1 
ATOM   161  C CG   . LEU A 1 13  ? 26.55120  -9.73096  20.26608  1.000 17.65269  ? 27  LEU A CG   1 
ATOM   162  C CD1  . LEU A 1 13  ? 28.00394  -9.96852  20.63239  1.000 19.86228  ? 27  LEU A CD1  1 
ATOM   163  C CD2  . LEU A 1 13  ? 26.27828  -8.23356  20.18821  1.000 17.60236  ? 27  LEU A CD2  1 
ATOM   164  H H    . LEU A 1 13  ? 24.14805  -11.09111 20.13954  1.000 15.37194  ? 27  LEU A H    1 
ATOM   165  H HA   . LEU A 1 13  ? 24.64949  -9.30246  18.34642  1.000 16.25475  ? 27  LEU A HA   1 
ATOM   166  H HB2  . LEU A 1 13  ? 26.35422  -11.40278 19.10706  1.000 18.80050  ? 27  LEU A HB2  1 
ATOM   167  H HB3  . LEU A 1 13  ? 26.82374  -10.12953 18.28013  1.000 18.80050  ? 27  LEU A HB3  1 
ATOM   168  H HG   . LEU A 1 13  ? 25.97757  -10.09150 20.96023  1.000 21.17812  ? 27  LEU A HG   1 
ATOM   169  H HD11 . LEU A 1 13  ? 28.16100  -10.92347 20.69799  1.000 23.82962  ? 27  LEU A HD11 1 
ATOM   170  H HD12 . LEU A 1 13  ? 28.56988  -9.58679  19.94327  1.000 23.82962  ? 27  LEU A HD12 1 
ATOM   171  H HD13 . LEU A 1 13  ? 28.18825  -9.54367  21.48470  1.000 23.82962  ? 27  LEU A HD13 1 
ATOM   172  H HD21 . LEU A 1 13  ? 25.32142  -8.09013  20.11926  1.000 21.11772  ? 27  LEU A HD21 1 
ATOM   173  H HD22 . LEU A 1 13  ? 26.61956  -7.80822  20.99040  1.000 21.11772  ? 27  LEU A HD22 1 
ATOM   174  H HD23 . LEU A 1 13  ? 26.72420  -7.87151  19.40656  1.000 21.11772  ? 27  LEU A HD23 1 
ATOM   175  N N    . PRO A 1 14  ? 24.28183  -12.18677 16.96319  1.000 11.70271  ? 28  PRO A N    1 
ATOM   176  C CA   . PRO A 1 14  ? 24.13712  -12.73971 15.61230  1.000 12.58823  ? 28  PRO A CA   1 
ATOM   177  C C    . PRO A 1 14  ? 23.04624  -12.05915 14.81844  1.000 12.84618  ? 28  PRO A C    1 
ATOM   178  O O    . PRO A 1 14  ? 23.26515  -11.73630 13.64788  1.000 14.34270  ? 28  PRO A O    1 
ATOM   179  C CB   . PRO A 1 14  ? 23.88443  -14.22846 15.86937  1.000 12.96240  ? 28  PRO A CB   1 
ATOM   180  C CG   . PRO A 1 14  ? 24.54990  -14.48207 17.19696  1.000 13.01450  ? 28  PRO A CG   1 
ATOM   181  C CD   . PRO A 1 14  ? 24.23459  -13.25063 17.98440  1.000 12.65018  ? 28  PRO A CD   1 
ATOM   182  H HA   . PRO A 1 14  ? 24.96773  -12.66566 15.11680  1.000 15.10077  ? 28  PRO A HA   1 
ATOM   183  H HB2  . PRO A 1 14  ? 22.93144  -14.40350 15.91478  0.747 15.54978  ? 28  PRO A HB2  1 
ATOM   184  H HB3  . PRO A 1 14  ? 24.28676  -14.76270 15.16679  1.000 15.54978  ? 28  PRO A HB3  1 
ATOM   185  H HG2  . PRO A 1 14  ? 24.17615  -15.27329 17.61551  1.000 15.61230  ? 28  PRO A HG2  1 
ATOM   186  H HG3  . PRO A 1 14  ? 25.50669  -14.58963 17.07917  1.000 15.61230  ? 28  PRO A HG3  1 
ATOM   187  H HD2  . PRO A 1 14  ? 23.35217  -13.31011 18.38278  1.000 15.17511  ? 28  PRO A HD2  1 
ATOM   188  H HD3  . PRO A 1 14  ? 24.90025  -13.09970 18.67361  1.000 15.17511  ? 28  PRO A HD3  1 
ATOM   189  N N    . VAL A 1 15  ? 21.90004  -11.76599 15.42709  1.000 11.51901  ? 29  VAL A N    1 
ATOM   190  C CA   . VAL A 1 15  ? 20.84596  -11.10486 14.65627  1.000 11.61649  ? 29  VAL A CA   1 
ATOM   191  C C    . VAL A 1 15  ? 21.15779  -9.62931  14.45153  1.000 12.18007  ? 29  VAL A C    1 
ATOM   192  O O    . VAL A 1 15  ? 20.86883  -9.07441  13.38448  1.000 12.40725  ? 29  VAL A O    1 
ATOM   193  C CB   . VAL A 1 15  ? 19.44119  -11.35938 15.23503  1.000 11.81166  ? 29  VAL A CB   1 
ATOM   194  C CG1  . VAL A 1 15  ? 19.18032  -10.57006 16.53735  1.000 12.30188  ? 29  VAL A CG1  1 
ATOM   195  C CG2  . VAL A 1 15  ? 18.39529  -11.04356 14.20498  1.000 13.19181  ? 29  VAL A CG2  1 
ATOM   196  H H    . VAL A 1 15  ? 21.71275  -11.93098 16.25007  1.000 13.81770  ? 29  VAL A H    1 
ATOM   197  H HA   . VAL A 1 15  ? 20.82860  -11.51449 13.77718  1.000 13.93468  ? 29  VAL A HA   1 
ATOM   198  H HB   . VAL A 1 15  ? 19.38537  -12.29899 15.46937  1.000 14.16889  ? 29  VAL A HB   1 
ATOM   199  H HG11 . VAL A 1 15  ? 18.31904  -10.83224 16.89839  0.682 14.75714  ? 29  VAL A HG11 1 
ATOM   200  H HG12 . VAL A 1 15  ? 19.88211  -10.77288 17.17552  1.000 14.75714  ? 29  VAL A HG12 1 
ATOM   201  H HG13 . VAL A 1 15  ? 19.17985  -9.62103  16.33672  1.000 14.75714  ? 29  VAL A HG13 1 
ATOM   202  H HG21 . VAL A 1 15  ? 18.78833  -11.12162 13.32161  1.000 15.82507  ? 29  VAL A HG21 1 
ATOM   203  H HG22 . VAL A 1 15  ? 17.66155  -11.67127 14.29720  0.421 15.82507  ? 29  VAL A HG22 1 
ATOM   204  H HG23 . VAL A 1 15  ? 18.07610  -10.13854 14.34621  0.914 15.82507  ? 29  VAL A HG23 1 
ATOM   205  N N    . LEU A 1 16  ? 21.80544  -8.97347  15.42046  1.000 11.56121  ? 30  LEU A N    1 
ATOM   206  C CA   . LEU A 1 16  ? 22.12866  -7.56786  15.22581  1.000 12.42523  ? 30  LEU A CA   1 
ATOM   207  C C    . LEU A 1 16  ? 23.12128  -7.39424  14.09308  1.000 12.60112  ? 30  LEU A C    1 
ATOM   208  O O    . LEU A 1 16  ? 23.10754  -6.36296  13.41631  1.000 13.49493  ? 30  LEU A O    1 
ATOM   209  C CB   . LEU A 1 16  ? 22.66090  -6.92894  16.50747  1.000 13.44128  ? 30  LEU A CB   1 
ATOM   210  C CG   . LEU A 1 16  ? 21.69712  -6.89798  17.68581  1.000 14.56427  ? 30  LEU A CG   1 
ATOM   211  C CD1  . LEU A 1 16  ? 22.36189  -6.23936  18.87079  1.000 15.78508  ? 30  LEU A CD1  1 
ATOM   212  C CD2  . LEU A 1 16  ? 20.39103  -6.18346  17.35083  1.000 14.68945  ? 30  LEU A CD2  1 
ATOM   213  H H    . LEU A 1 16  ? 22.05745  -9.31098  16.17025  1.000 13.86834  ? 30  LEU A H    1 
ATOM   214  H HA   . LEU A 1 16  ? 21.31106  -7.09581  15.00310  1.000 14.90517  ? 30  LEU A HA   1 
ATOM   215  H HB2  . LEU A 1 16  ? 23.44484  -7.42534  16.79020  1.000 16.12443  ? 30  LEU A HB2  1 
ATOM   216  H HB3  . LEU A 1 16  ? 22.90311  -6.01067  16.30993  1.000 16.12443  ? 30  LEU A HB3  1 
ATOM   217  H HG   . LEU A 1 16  ? 21.46546  -7.81287  17.90990  1.000 17.47202  ? 30  LEU A HG   1 
ATOM   218  H HD11 . LEU A 1 16  ? 21.73496  -6.21348  19.61051  1.000 18.93698  ? 30  LEU A HD11 1 
ATOM   219  H HD12 . LEU A 1 16  ? 23.14575  -6.75382  19.11938  1.000 18.93698  ? 30  LEU A HD12 1 
ATOM   220  H HD13 . LEU A 1 16  ? 22.62207  -5.33754  18.62599  1.000 18.93698  ? 30  LEU A HD13 1 
ATOM   221  H HD21 . LEU A 1 16  ? 19.84627  -6.12937  18.15159  1.000 17.62223  ? 30  LEU A HD21 1 
ATOM   222  H HD22 . LEU A 1 16  ? 20.59296  -5.29158  17.02728  0.742 17.62223  ? 30  LEU A HD22 1 
ATOM   223  H HD23 . LEU A 1 16  ? 19.92297  -6.68580  16.66565  0.677 17.62223  ? 30  LEU A HD23 1 
ATOM   224  N N    . ASN A 1 17  ? 23.97658  -8.39633  13.87734  1.000 12.33755  ? 31  ASN A N    1 
ATOM   225  C CA   . ASN A 1 17  ? 24.90589  -8.40024  12.75440  1.000 13.13561  ? 31  ASN A CA   1 
ATOM   226  C C    . ASN A 1 17  ? 24.21103  -8.57655  11.41452  1.000 12.87789  ? 31  ASN A C    1 
ATOM   227  O O    . ASN A 1 17  ? 24.86785  -8.47291  10.37466  1.000 13.72581  ? 31  ASN A O    1 
ATOM   228  C CB   . ASN A 1 17  ? 25.89132  -9.54477  12.96362  1.000 14.16391  ? 31  ASN A CB   1 
ATOM   229  C CG   . ASN A 1 17  ? 26.99404  -9.56485  11.93648  1.000 15.34760  ? 31  ASN A CG   1 
ATOM   230  O OD1  . ASN A 1 17  ? 27.64079  -8.54742  11.66644  1.000 16.10830  ? 31  ASN A OD1  1 
ATOM   231  N ND2  . ASN A 1 17  ? 27.21554  -10.73007 11.34564  1.000 16.73315  ? 31  ASN A ND2  1 
ATOM   232  H H    . ASN A 1 17  ? 24.03701  -9.09447  14.37589  0.917 14.79995  ? 31  ASN A H    1 
ATOM   233  H HA   . ASN A 1 17  ? 25.38468  -7.55722  12.72328  1.000 15.75763  ? 31  ASN A HA   1 
ATOM   234  H HB2  . ASN A 1 17  ? 26.29928  -9.45380  13.83894  0.377 16.99158  ? 31  ASN A HB2  1 
ATOM   235  H HB3  . ASN A 1 17  ? 25.41349  -10.38696 12.90620  1.000 16.99158  ? 31  ASN A HB3  1 
ATOM   236  H HD21 . ASN A 1 17  ? 26.74192  -11.41615 11.55676  1.000 20.07467  ? 31  ASN A HD21 1 
ATOM   237  H HD22 . ASN A 1 17  ? 27.83293  -10.80022 10.75107  1.000 20.07467  ? 31  ASN A HD22 1 
ATOM   238  N N    . GLU A 1 18  ? 22.91027  -8.85266  11.42394  1.000 12.54462  ? 32  GLU A N    1 
ATOM   239  C CA   . GLU A 1 18  ? 22.10854  -9.10121  10.23840  1.000 12.98504  ? 32  GLU A CA   1 
ATOM   240  C C    . GLU A 1 18  ? 20.82095  -8.29248  10.28048  1.000 11.70916  ? 32  GLU A C    1 
ATOM   241  O O    . GLU A 1 18  ? 19.79017  -8.74506  9.79793   1.000 11.93844  ? 32  GLU A O    1 
ATOM   242  C CB   . GLU A 1 18  ? 21.79071  -10.59349 10.10323  1.000 16.66786  ? 32  GLU A CB   1 
ATOM   243  C CG   . GLU A 1 18  ? 23.00901  -11.48267 10.10701  1.000 20.37578  ? 32  GLU A CG   1 
ATOM   244  C CD   . GLU A 1 18  ? 22.69451  -12.92769 9.75993   1.000 22.46162  ? 32  GLU A CD   1 
ATOM   245  O OE1  . GLU A 1 18  ? 21.58264  -13.19545 9.23645   1.000 23.47699  ? 32  GLU A OE1  1 
ATOM   246  O OE2  . GLU A 1 18  ? 23.57797  -13.79308 9.99911   1.000 24.10337  ? 32  GLU A OE2  1 
ATOM   247  H H    . GLU A 1 18  ? 22.44708  -8.90365  12.14675  1.000 15.04843  ? 32  GLU A H    1 
ATOM   248  H HA   . GLU A 1 18  ? 22.61249  -8.82712  9.45622   1.000 15.57694  ? 32  GLU A HA   1 
ATOM   249  H HB2  . GLU A 1 18  ? 21.22831  -10.86022 10.84718  1.000 19.99632  ? 32  GLU A HB2  1 
ATOM   250  H HB3  . GLU A 1 18  ? 21.32305  -10.73714 9.26564   1.000 19.99632  ? 32  GLU A HB3  1 
ATOM   251  H HG2  . GLU A 1 18  ? 23.64332  -11.15002 9.45287   1.000 24.44583  ? 32  GLU A HG2  1 
ATOM   252  H HG3  . GLU A 1 18  ? 23.40641  -11.46808 10.99175  1.000 24.44583  ? 32  GLU A HG3  1 
ATOM   253  N N    . ALA A 1 19  ? 20.86251  -7.08886  10.84295  1.000 11.97413  ? 33  ALA A N    1 
ATOM   254  C CA   . ALA A 1 19  ? 19.64921  -6.30985  10.98963  1.000 11.64513  ? 33  ALA A CA   1 
ATOM   255  C C    . ALA A 1 19  ? 19.98258  -4.83426  11.05124  1.000 11.72167  ? 33  ALA A C    1 
ATOM   256  O O    . ALA A 1 19  ? 21.04981  -4.44539  11.51987  1.000 13.24219  ? 33  ALA A O    1 
ATOM   257  C CB   . ALA A 1 19  ? 18.90722  -6.69228  12.26491  1.000 12.63221  ? 33  ALA A CB   1 
ATOM   258  H H    . ALA A 1 19  ? 21.57433  -6.71034  11.14232  1.000 14.36385  ? 33  ALA A H    1 
ATOM   259  H HA   . ALA A 1 19  ? 19.08594  -6.46574  10.21547  1.000 13.96905  ? 33  ALA A HA   1 
ATOM   260  H HB1  . ALA A 1 19  ? 19.36128  -6.29648  13.02522  1.000 15.15354  ? 33  ALA A HB1  1 
ATOM   261  H HB2  . ALA A 1 19  ? 17.99758  -6.35948  12.21290  1.000 15.15354  ? 33  ALA A HB2  1 
ATOM   262  H HB3  . ALA A 1 19  ? 18.90158  -7.65858  12.34930  1.000 15.15354  ? 33  ALA A HB3  1 
ATOM   263  N N    . LYS A 1 20  ? 19.03234  -4.02169  10.60428  1.000 11.79546  ? 34  LYS A N    1 
ATOM   264  C CA   . LYS A 1 20  ? 18.95966  -2.61408  10.95139  1.000 11.81229  ? 34  LYS A CA   1 
ATOM   265  C C    . LYS A 1 20  ? 17.72372  -2.41911  11.81380  1.000 11.70745  ? 34  LYS A C    1 
ATOM   266  O O    . LYS A 1 20  ? 16.77996  -3.21558  11.77550  1.000 11.91878  ? 34  LYS A O    1 
ATOM   267  C CB   . LYS A 1 20  ? 18.86912  -1.71430  9.70520   1.000 12.25277  ? 34  LYS A CB   1 
ATOM   268  C CG   . LYS A 1 20  ? 17.59861  -1.92057  8.90516   1.000 12.51022  ? 34  LYS A CG   1 
ATOM   269  C CD   . LYS A 1 20  ? 17.47276  -0.98291  7.70920   1.000 13.94609  ? 34  LYS A CD   1 
ATOM   270  C CE   . LYS A 1 20  ? 16.27270  -1.36224  6.85590   1.000 15.02002  ? 34  LYS A CE   1 
ATOM   271  N NZ   . LYS A 1 20  ? 16.04845  -0.39874  5.74085   1.000 15.67800  ? 34  LYS A NZ   1 
ATOM   272  H H    . LYS A 1 20  ? 18.39842  -4.27430  10.08089  1.000 14.14944  ? 34  LYS A H    1 
ATOM   273  H HA   . LYS A 1 20  ? 19.75818  -2.34517  11.43197  1.000 14.16964  ? 34  LYS A HA   1 
ATOM   274  H HB2  . LYS A 1 20  ? 18.89659  -0.78631  9.98625   1.000 14.69821  ? 34  LYS A HB2  1 
ATOM   275  H HB3  . LYS A 1 20  ? 19.62146  -1.90737  9.12416   1.000 14.69821  ? 34  LYS A HB3  1 
ATOM   276  H HG2  . LYS A 1 20  ? 17.58314  -2.83093  8.57066   1.000 15.00715  ? 34  LYS A HG2  1 
ATOM   277  H HG3  . LYS A 1 20  ? 16.83540  -1.76669  9.48373   0.579 15.00715  ? 34  LYS A HG3  1 
ATOM   278  H HD2  . LYS A 1 20  ? 17.35386  -0.07232  8.02159   1.000 16.73020  ? 34  LYS A HD2  1 
ATOM   279  H HD3  . LYS A 1 20  ? 18.27183  -1.04452  7.16277   1.000 16.73020  ? 34  LYS A HD3  1 
ATOM   280  H HE2  . LYS A 1 20  ? 16.42004  -2.24051  6.47140   1.000 18.01891  ? 34  LYS A HE2  1 
ATOM   281  H HE3  . LYS A 1 20  ? 15.47740  -1.37234  7.41115   1.000 18.01891  ? 34  LYS A HE3  1 
ATOM   282  H HZ1  . LYS A 1 20  ? 15.40721  -0.70027  5.20234   1.000 18.80849  ? 34  LYS A HZ1  1 
ATOM   283  H HZ2  . LYS A 1 20  ? 15.80359  0.39240   6.06678   1.000 18.80849  ? 34  LYS A HZ2  1 
ATOM   284  H HZ3  . LYS A 1 20  ? 16.79716  -0.29810  5.27031   1.000 18.80849  ? 34  LYS A HZ3  1 
ATOM   285  N N    . LEU A 1 21  ? 17.70955  -1.32765  12.56315  1.000 11.29763  ? 35  LEU A N    1 
ATOM   286  C CA   . LEU A 1 21  ? 16.55147  -0.95373  13.35906  1.000 11.38422  ? 35  LEU A CA   1 
ATOM   287  C C    . LEU A 1 21  ? 15.82520  0.17731   12.65836  1.000 11.19153  ? 35  LEU A C    1 
ATOM   288  O O    . LEU A 1 21  ? 16.44698  1.17109   12.27019  1.000 12.06140  ? 35  LEU A O    1 
ATOM   289  C CB   . LEU A 1 21  ? 16.95773  -0.49247  14.75588  1.000 11.78580  ? 35  LEU A CB   1 
ATOM   290  C CG   . LEU A 1 21  ? 15.78735  -0.27601  15.72367  1.000 11.95321  ? 35  LEU A CG   1 
ATOM   291  C CD1  . LEU A 1 21  ? 15.15990  -1.59006  16.17631  1.000 13.45318  ? 35  LEU A CD1  1 
ATOM   292  C CD2  . LEU A 1 21  ? 16.23821  0.57225   16.91068  1.000 12.75687  ? 35  LEU A CD2  1 
ATOM   293  H H    . LEU A 1 21  ? 18.36886  -0.77930  12.62803  0.819 13.55204  ? 35  LEU A H    1 
ATOM   294  H HA   . LEU A 1 21  ? 15.96505  -1.72122  13.44839  1.000 13.65596  ? 35  LEU A HA   1 
ATOM   295  H HB2  . LEU A 1 21  ? 17.53914  -1.16445  15.14485  0.699 14.13786  ? 35  LEU A HB2  1 
ATOM   296  H HB3  . LEU A 1 21  ? 17.43156  0.35015   14.67599  0.636 14.13786  ? 35  LEU A HB3  1 
ATOM   297  H HG   . LEU A 1 21  ? 15.08653  0.20454   15.25588  1.000 14.33875  ? 35  LEU A HG   1 
ATOM   298  H HD11 . LEU A 1 21  ? 14.94769  -2.12433  15.39501  1.000 16.13871  ? 35  LEU A HD11 1 
ATOM   299  H HD12 . LEU A 1 21  ? 15.79149  -2.06410  16.73958  1.000 16.13871  ? 35  LEU A HD12 1 
ATOM   300  H HD13 . LEU A 1 21  ? 14.35068  -1.39817  16.67555  0.861 16.13871  ? 35  LEU A HD13 1 
ATOM   301  H HD21 . LEU A 1 21  ? 15.47626  0.73868   17.48742  1.000 15.30314  ? 35  LEU A HD21 1 
ATOM   302  H HD22 . LEU A 1 21  ? 16.92446  0.09177   17.39965  1.000 15.30314  ? 35  LEU A HD22 1 
ATOM   303  H HD23 . LEU A 1 21  ? 16.59364  1.41259   16.58142  1.000 15.30314  ? 35  LEU A HD23 1 
ATOM   304  N N    . GLN A 1 22  ? 14.52533  -0.00310  12.46927  1.000 11.58249  ? 36  GLN A N    1 
ATOM   305  C CA   . GLN A 1 22  ? 13.62347  1.00918   11.94673  1.000 11.79569  ? 36  GLN A CA   1 
ATOM   306  C C    . GLN A 1 22  ? 12.78317  1.53124   13.09890  1.000 11.19628  ? 36  GLN A C    1 
ATOM   307  O O    . GLN A 1 22  ? 12.14359  0.74690   13.81073  1.000 11.67109  ? 36  GLN A O    1 
ATOM   308  C CB   . GLN A 1 22  ? 12.71825  0.40017   10.88299  1.000 12.34913  ? 36  GLN A CB   1 
ATOM   309  C CG   . GLN A 1 22  ? 13.49795  -0.07231  9.68980   1.000 13.63474  ? 36  GLN A CG   1 
ATOM   310  C CD   . GLN A 1 22  ? 12.62488  -0.78158  8.69894   1.000 15.65856  ? 36  GLN A CD   1 
ATOM   311  O OE1  . GLN A 1 22  ? 11.97833  -1.76668  9.03948   1.000 17.18769  ? 36  GLN A OE1  1 
ATOM   312  N NE2  . GLN A 1 22  ? 12.59542  -0.29308  7.47227   1.000 17.16643  ? 36  GLN A NE2  1 
ATOM   313  H H    . GLN A 1 22  ? 14.12326  -0.74250  12.64597  1.000 13.89388  ? 36  GLN A H    1 
ATOM   314  H HA   . GLN A 1 22  ? 14.12650  1.74268   11.55964  0.374 14.14973  ? 36  GLN A HA   1 
ATOM   315  H HB2  . GLN A 1 22  ? 12.24905  -0.36029  11.26042  0.893 14.81384  ? 36  GLN A HB2  1 
ATOM   316  H HB3  . GLN A 1 22  ? 12.08139  1.06844   10.58512  0.938 14.81384  ? 36  GLN A HB3  1 
ATOM   317  H HG2  . GLN A 1 22  ? 13.90049  0.69168   9.24799   1.000 16.35658  ? 36  GLN A HG2  1 
ATOM   318  H HG3  . GLN A 1 22  ? 14.18806  -0.68804  9.98224   0.281 16.35658  ? 36  GLN A HG3  1 
ATOM   319  H HE21 . GLN A 1 22  ? 13.06367  0.40057   7.27430   1.000 20.59461  ? 36  GLN A HE21 1 
ATOM   320  H HE22 . GLN A 1 22  ? 12.10798  -0.66863  6.87146   1.000 20.59461  ? 36  GLN A HE22 1 
ATOM   321  N N    . TRP A 1 23  ? 12.80580  2.84423   13.29269  1.000 11.48721  ? 37  TRP A N    1 
ATOM   322  C CA   . TRP A 1 23  ? 12.07199  3.49422   14.37215  1.000 12.14130  ? 37  TRP A CA   1 
ATOM   323  C C    . TRP A 1 23  ? 12.12418  4.98835   14.12898  1.000 12.42488  ? 37  TRP A C    1 
ATOM   324  O O    . TRP A 1 23  ? 13.16751  5.49850   13.70167  1.000 13.73825  ? 37  TRP A O    1 
ATOM   325  C CB   . TRP A 1 23  ? 12.73835  3.20718   15.72139  1.000 12.77241  ? 37  TRP A CB   1 
ATOM   326  C CG   . TRP A 1 23  ? 12.25668  4.06190   16.86249  1.000 12.68196  ? 37  TRP A CG   1 
ATOM   327  C CD1  . TRP A 1 23  ? 11.19075  3.81874   17.67763  1.000 12.72098  ? 37  TRP A CD1  1 
ATOM   328  C CD2  . TRP A 1 23  ? 12.84016  5.29201   17.31440  1.000 12.62028  ? 37  TRP A CD2  1 
ATOM   329  N NE1  . TRP A 1 23  ? 11.07422  4.82546   18.60888  1.000 12.36507  ? 37  TRP A NE1  1 
ATOM   330  C CE2  . TRP A 1 23  ? 12.08348  5.73221   18.41843  1.000 13.06532  ? 37  TRP A CE2  1 
ATOM   331  C CE3  . TRP A 1 23  ? 13.93965  6.05215   16.90305  1.000 13.68831  ? 37  TRP A CE3  1 
ATOM   332  C CZ2  . TRP A 1 23  ? 12.38768  6.89511   19.11679  1.000 14.05889  ? 37  TRP A CZ2  1 
ATOM   333  C CZ3  . TRP A 1 23  ? 14.23489  7.21608   17.59866  1.000 14.50846  ? 37  TRP A CZ3  1 
ATOM   334  C CH2  . TRP A 1 23  ? 13.46428  7.62181   18.69044  1.000 14.89401  ? 37  TRP A CH2  1 
ATOM   335  H H    . TRP A 1 23  ? 13.24878  3.39391   12.80154  1.000 13.77954  ? 37  TRP A H    1 
ATOM   336  H HA   . TRP A 1 23  ? 11.15720  3.17245   14.39493  1.000 14.56446  ? 37  TRP A HA   1 
ATOM   337  H HB2  . TRP A 1 23  ? 12.56673  2.28232   15.95822  1.000 15.32179  ? 37  TRP A HB2  1 
ATOM   338  H HB3  . TRP A 1 23  ? 13.69272  3.35470   15.63026  1.000 15.32179  ? 37  TRP A HB3  1 
ATOM   339  H HD1  . TRP A 1 23  ? 10.62651  3.08222   17.61375  1.000 15.26006  ? 37  TRP A HD1  1 
ATOM   340  H HE1  . TRP A 1 23  ? 10.46510  4.87709   19.21378  1.000 14.83297  ? 37  TRP A HE1  1 
ATOM   341  H HE3  . TRP A 1 23  ? 14.46043  5.78405   16.18069  1.000 16.42086  ? 37  TRP A HE3  1 
ATOM   342  H HZ2  . TRP A 1 23  ? 11.87862  7.16808   19.84565  1.000 16.86556  ? 37  TRP A HZ2  1 
ATOM   343  H HZ3  . TRP A 1 23  ? 14.95916  7.73543   17.33294  1.000 17.40504  ? 37  TRP A HZ3  1 
ATOM   344  H HH2  . TRP A 1 23  ? 13.68895  8.40531   19.13827  0.224 17.86770  ? 37  TRP A HH2  1 
ATOM   345  N N    . PRO A 1 24  ? 11.04317  5.72585   14.40747  1.000 12.79005  ? 38  PRO A N    1 
ATOM   346  C CA   . PRO A 1 24  ? 9.70769   5.28162   14.83877  1.000 12.94561  ? 38  PRO A CA   1 
ATOM   347  C C    . PRO A 1 24  ? 8.81201   4.89885   13.66423  1.000 13.27038  ? 38  PRO A C    1 
ATOM   348  O O    . PRO A 1 24  ? 7.65048   4.56566   13.85806  1.000 13.71118  ? 38  PRO A O    1 
ATOM   349  C CB   . PRO A 1 24  ? 9.18959   6.49778   15.59776  1.000 14.50261  ? 38  PRO A CB   1 
ATOM   350  C CG   . PRO A 1 24  ? 9.76621   7.64004   14.84869  1.000 15.18834  ? 38  PRO A CG   1 
ATOM   351  C CD   . PRO A 1 24  ? 11.13793  7.19209   14.42009  1.000 13.82810  ? 38  PRO A CD   1 
ATOM   352  H HA   . PRO A 1 24  ? 9.77494   4.52604   15.44331  1.000 15.52962  ? 38  PRO A HA   1 
ATOM   353  H HB2  . PRO A 1 24  ? 8.21994   6.51741   15.58050  1.000 17.39802  ? 38  PRO A HB2  1 
ATOM   354  H HB3  . PRO A 1 24  ? 9.50481   6.48160   16.51497  1.000 17.39802  ? 38  PRO A HB3  1 
ATOM   355  H HG2  . PRO A 1 24  ? 9.21236   7.83981   14.07782  1.000 18.22089  ? 38  PRO A HG2  1 
ATOM   356  H HG3  . PRO A 1 24  ? 9.82234   8.41670   15.42709  1.000 18.22089  ? 38  PRO A HG3  1 
ATOM   357  H HD2  . PRO A 1 24  ? 11.34794  7.52969   13.53531  0.788 16.58861  ? 38  PRO A HD2  1 
ATOM   358  H HD3  . PRO A 1 24  ? 11.80895  7.48682   15.05553  1.000 16.58861  ? 38  PRO A HD3  1 
ATOM   359  N N    . THR A 1 25  ? 9.35302   4.98054   12.45076  1.000 14.19927  ? 39  THR A N    1 
ATOM   360  C CA   . THR A 1 25  ? 8.66103   4.57905   11.22811  1.000 15.32948  ? 39  THR A CA   1 
ATOM   361  C C    . THR A 1 25  ? 9.60056   3.62063   10.49858  1.000 14.42816  ? 39  THR A C    1 
ATOM   362  O O    . THR A 1 25  ? 10.52177  3.04190   11.08398  1.000 15.17739  ? 39  THR A O    1 
ATOM   363  C CB   . THR A 1 25  ? 8.34158   5.80485   10.36974  1.000 17.23484  ? 39  THR A CB   1 
ATOM   364  O OG1  . THR A 1 25  ? 9.57070   6.40353   9.93901   1.000 18.61091  ? 39  THR A OG1  1 
ATOM   365  C CG2  . THR A 1 25  ? 7.50716   6.81252   11.16315  1.000 18.62918  ? 39  THR A CG2  1 
ATOM   366  H H    . THR A 1 25  ? 10.14742  5.27551   12.30405  1.000 17.03402  ? 39  THR A H    1 
ATOM   367  H HA   . THR A 1 25  ? 7.83074   4.13475   11.46076  1.000 18.39027  ? 39  THR A HA   1 
ATOM   368  H HB   . THR A 1 25  ? 7.82292   5.54541   9.59220   1.000 20.67670  ? 39  THR A HB   1 
ATOM   369  H HG1  . THR A 1 25  ? 9.96421   6.75411   10.59310  1.000 22.32798  ? 39  THR A HG1  1 
ATOM   370  H HG21 . THR A 1 25  ? 7.49455   7.66707   10.70436  1.000 22.34991  ? 39  THR A HG21 1 
ATOM   371  H HG22 . THR A 1 25  ? 6.59667   6.49064   11.25419  1.000 22.34991  ? 39  THR A HG22 1 
ATOM   372  H HG23 . THR A 1 25  ? 7.88750   6.93532   12.04698  0.642 22.34991  ? 39  THR A HG23 1 
ATOM   373  N N    . SER A 1 26  ? 9.40110   3.45011   9.19175   1.000 15.24285  ? 40  SER A N    1 
ATOM   374  C CA   . SER A 1 26  ? 10.35739  2.66147   8.42362   1.000 15.46965  ? 40  SER A CA   1 
ATOM   375  C C    . SER A 1 26  ? 11.69169  3.37374   8.21986   1.000 15.98402  ? 40  SER A C    1 
ATOM   376  O O    . SER A 1 26  ? 12.61115  2.75580   7.67199   1.000 17.10271  ? 40  SER A O    1 
ATOM   377  C CB   . SER A 1 26  ? 9.73600   2.24370   7.09168   1.000 16.98421  ? 40  SER A CB   1 
ATOM   378  O OG   . SER A 1 26  ? 8.64481   1.37405   7.33377   1.000 18.31626  ? 40  SER A OG   1 
ATOM   379  H H    . SER A 1 26  ? 8.74106   3.77100   8.74344   1.000 18.28631  ? 40  SER A H    1 
ATOM   380  H HA   . SER A 1 26  ? 10.55580  1.84412   8.90682   1.000 18.55848  ? 40  SER A HA   1 
ATOM   381  H HB2  . SER A 1 26  ? 9.42084   3.03209   6.62262   0.938 20.37595  ? 40  SER A HB2  1 
ATOM   382  H HB3  . SER A 1 26  ? 10.40148  1.78332   6.55681   1.000 20.37595  ? 40  SER A HB3  1 
ATOM   383  H HG   . SER A 1 26  ? 8.89978   0.71113   7.78224   0.449 21.97440  ? 40  SER A HG   1 
ATOM   384  N N    . ALA A 1 27  ? 11.81811  4.62779   8.64877   1.000 16.86911  ? 41  ALA A N    1 
ATOM   385  C CA   . ALA A 1 27  ? 13.09692  5.31547   8.58269   1.000 17.29485  ? 41  ALA A CA   1 
ATOM   386  C C    . ALA A 1 27  ? 14.15459  4.59437   9.41284   1.000 15.42959  ? 41  ALA A C    1 
ATOM   387  O O    . ALA A 1 27  ? 13.86873  3.99633   10.45342  1.000 15.70226  ? 41  ALA A O    1 
ATOM   388  C CB   . ALA A 1 27  ? 12.94047  6.74125   9.10197   1.000 19.15146  ? 41  ALA A CB   1 
ATOM   389  H H    . ALA A 1 27  ? 11.17930  5.09831   8.98064   1.000 20.23782  ? 41  ALA A H    1 
ATOM   390  H HA   . ALA A 1 27  ? 13.39796  5.33794   7.66087   1.000 20.74871  ? 41  ALA A HA   1 
ATOM   391  H HB1  . ALA A 1 27  ? 12.62926  6.71056   10.02017  1.000 22.97664  ? 41  ALA A HB1  1 
ATOM   392  H HB2  . ALA A 1 27  ? 13.79978  7.18915   9.05875   0.091 22.97664  ? 41  ALA A HB2  1 
ATOM   393  H HB3  . ALA A 1 27  ? 12.29521  7.20954   8.54948   0.074 22.97664  ? 41  ALA A HB3  1 
ATOM   394  N N    . LEU A 1 28  ? 15.39323  4.67544   8.94075   1.000 15.51638  ? 42  LEU A N    1 
ATOM   395  C CA   . LEU A 1 28  ? 16.50859  4.06302   9.63572   1.000 14.81250  ? 42  LEU A CA   1 
ATOM   396  C C    . LEU A 1 28  ? 16.70508  4.73806   10.97858  1.000 14.90702  ? 42  LEU A C    1 
ATOM   397  O O    . LEU A 1 28  ? 16.82839  5.96076   11.06837  1.000 16.63606  ? 42  LEU A O    1 
ATOM   398  C CB   . LEU A 1 28  ? 17.77222  4.22438   8.80075   1.000 15.78403  ? 42  LEU A CB   1 
ATOM   399  C CG   . LEU A 1 28  ? 19.04048  3.62550   9.40043   1.000 16.97144  ? 42  LEU A CG   1 
ATOM   400  C CD1  . LEU A 1 28  ? 18.93430  2.11093   9.52094   1.000 16.95091  ? 42  LEU A CD1  1 
ATOM   401  C CD2  . LEU A 1 28  ? 20.22670  4.02418   8.54529   1.000 18.91298  ? 42  LEU A CD2  1 
ATOM   402  H H    . LEU A 1 28  ? 15.61250  5.08243   8.21557   1.000 18.61454  ? 42  LEU A H    1 
ATOM   403  H HA   . LEU A 1 28  ? 16.33593  3.11861   9.77419   1.000 17.76989  ? 42  LEU A HA   1 
ATOM   404  H HB2  . LEU A 1 28  ? 17.62702  3.79408   7.94363   1.000 18.93573  ? 42  LEU A HB2  1 
ATOM   405  H HB3  . LEU A 1 28  ? 17.93298  5.17240   8.67304   0.928 18.93573  ? 42  LEU A HB3  1 
ATOM   406  H HG   . LEU A 1 28  ? 19.16987  3.96658   10.29922  1.000 20.36062  ? 42  LEU A HG   1 
ATOM   407  H HD11 . LEU A 1 28  ? 18.18423  1.89167   10.09558  1.000 20.33598  ? 42  LEU A HD11 1 
ATOM   408  H HD12 . LEU A 1 28  ? 18.79646  1.73280   8.63837   1.000 20.33598  ? 42  LEU A HD12 1 
ATOM   409  H HD13 . LEU A 1 28  ? 19.75617  1.76621   9.90382   1.000 20.33598  ? 42  LEU A HD13 1 
ATOM   410  H HD21 . LEU A 1 28  ? 20.27315  4.99206   8.50123   1.000 22.69047  ? 42  LEU A HD21 1 
ATOM   411  H HD22 . LEU A 1 28  ? 21.03708  3.67201   8.94550   1.000 22.69047  ? 42  LEU A HD22 1 
ATOM   412  H HD23 . LEU A 1 28  ? 20.11133  3.65766   7.65464   0.234 22.69047  ? 42  LEU A HD23 1 
ATOM   413  N N    . ALA A 1 29  ? 16.73713  3.92832   12.02928  1.000 13.47774  ? 43  ALA A N    1 
ATOM   414  C CA   . ALA A 1 29  ? 17.10742  4.38080   13.36093  1.000 13.26155  ? 43  ALA A CA   1 
ATOM   415  C C    . ALA A 1 29  ? 18.52919  3.99971   13.72161  1.000 12.91929  ? 43  ALA A C    1 
ATOM   416  O O    . ALA A 1 29  ? 19.22579  4.78250   14.35761  1.000 14.18193  ? 43  ALA A O    1 
ATOM   417  C CB   . ALA A 1 29  ? 16.15530  3.79286   14.40354  1.000 13.29794  ? 43  ALA A CB   1 
ATOM   418  H H    . ALA A 1 29  ? 16.54336  3.09118   11.99403  1.000 16.16818  ? 43  ALA A H    1 
ATOM   419  H HA   . ALA A 1 29  ? 17.02854  5.34684   13.39881  1.000 15.90875  ? 43  ALA A HA   1 
ATOM   420  H HB1  . ALA A 1 29  ? 16.44840  4.06422   15.28749  1.000 15.95242  ? 43  ALA A HB1  1 
ATOM   421  H HB2  . ALA A 1 29  ? 15.25939  4.12468   14.23577  1.000 15.95242  ? 43  ALA A HB2  1 
ATOM   422  H HB3  . ALA A 1 29  ? 16.16833  2.82551   14.33320  1.000 15.95242  ? 43  ALA A HB3  1 
ATOM   423  N N    . ALA A 1 30  ? 18.97027  2.80658   13.33395  1.000 12.90441  ? 44  ALA A N    1 
ATOM   424  C CA   . ALA A 1 30  ? 20.31366  2.34637   13.65517  1.000 12.63881  ? 44  ALA A CA   1 
ATOM   425  C C    . ALA A 1 30  ? 20.72359  1.29349   12.63959  1.000 13.14227  ? 44  ALA A C    1 
ATOM   426  O O    . ALA A 1 30  ? 20.00149  0.32059   12.41119  1.000 13.01939  ? 44  ALA A O    1 
ATOM   427  C CB   . ALA A 1 30  ? 20.37452  1.76096   15.07182  1.000 12.75011  ? 44  ALA A CB   1 
ATOM   428  H H    . ALA A 1 30  ? 18.50620  2.24204   12.88058  0.242 15.48018  ? 44  ALA A H    1 
ATOM   429  H HA   . ALA A 1 30  ? 20.93155  3.09212   13.60070  0.652 15.16147  ? 44  ALA A HA   1 
ATOM   430  H HB1  . ALA A 1 30  ? 19.83877  0.95293   15.10290  1.000 15.29502  ? 44  ALA A HB1  1 
ATOM   431  H HB2  . ALA A 1 30  ? 21.29713  1.55467   15.28892  1.000 15.29502  ? 44  ALA A HB2  1 
ATOM   432  H HB3  . ALA A 1 30  ? 20.02523  2.41374   15.69854  1.000 15.29502  ? 44  ALA A HB3  1 
ATOM   433  N N    . SER A 1 31  ? 21.89700  1.47569   12.05594  1.000 13.10885  ? 45  SER A N    1 
ATOM   434  C CA   . SER A 1 31  ? 22.44899  0.44740   11.20110  1.000 13.71816  ? 45  SER A CA   1 
ATOM   435  C C    . SER A 1 31  ? 22.90296  -0.73462  12.05367  1.000 12.97257  ? 45  SER A C    1 
ATOM   436  O O    . SER A 1 31  ? 23.02836  -0.63974  13.27304  1.000 13.17266  ? 45  SER A O    1 
ATOM   437  C CB   . SER A 1 31  ? 23.65933  0.99473   10.46182  1.000 14.87055  ? 45  SER A CB   1 
ATOM   438  O OG   . SER A 1 31  ? 24.69482  1.27027   11.38579  1.000 16.35530  ? 45  SER A OG   1 
ATOM   439  H H    . SER A 1 31  ? 22.38575  2.17838   12.13934  0.766 15.72551  ? 45  SER A H    1 
ATOM   440  H HA   . SER A 1 31  ? 21.77810  0.15681   10.56363  1.000 16.45669  ? 45  SER A HA   1 
ATOM   441  H HB2  . SER A 1 31  ? 23.96853  0.33583   9.82061   1.000 17.83955  ? 45  SER A HB2  1 
ATOM   442  H HB3  . SER A 1 31  ? 23.41220  1.81315   10.00353  1.000 17.83955  ? 45  SER A HB3  1 
ATOM   443  H HG   . SER A 1 31  ? 24.39031  1.70364   12.03776  1.000 19.62125  ? 45  SER A HG   1 
ATOM   444  N N    . SER A 1 32  ? 23.17433  -1.85412  11.38618  1.000 13.48598  ? 46  SER A N    1 
ATOM   445  C CA   . SER A 1 32  ? 23.74787  -3.01671  12.05426  1.000 13.31069  ? 46  SER A CA   1 
ATOM   446  C C    . SER A 1 32  ? 24.99211  -2.63300  12.84594  1.000 13.81366  ? 46  SER A C    1 
ATOM   447  O O    . SER A 1 32  ? 25.15721  -3.02541  14.00576  1.000 13.99335  ? 46  SER A O    1 
ATOM   448  C CB   . SER A 1 32  ? 24.09822  -4.06231  10.99875  1.000 14.20218  ? 46  SER A CB   1 
ATOM   449  O OG   . SER A 1 32  ? 24.68726  -5.20150  11.58785  1.000 14.69859  ? 46  SER A OG   1 
ATOM   450  H H    . SER A 1 32  ? 23.03550  -1.96611  10.54488  1.000 16.17807  ? 46  SER A H    1 
ATOM   451  H HA   . SER A 1 32  ? 23.10045  -3.38961  12.67289  1.000 15.96772  ? 46  SER A HA   1 
ATOM   452  H HB2  . SER A 1 32  ? 23.28693  -4.32961  10.53911  1.000 17.03751  ? 46  SER A HB2  1 
ATOM   453  H HB3  . SER A 1 32  ? 24.72473  -3.67480  10.36770  1.000 17.03751  ? 46  SER A HB3  1 
ATOM   454  H HG   . SER A 1 32  ? 24.22704  -5.45684  12.24252  0.677 17.63320  ? 46  SER A HG   1 
ATOM   455  N N    . GLU A 1 33  ? 25.87680  -1.84953  12.23411  1.000 15.03372  ? 47  GLU A N    1 
ATOM   456  C CA   A GLU A 1 33  ? 27.09189  -1.44191  12.92751  0.462 16.93499  ? 47  GLU A CA   1 
ATOM   457  C CA   B GLU A 1 33  ? 27.09312  -1.43556  12.92632  0.538 16.60113  ? 47  GLU A CA   1 
ATOM   458  C C    . GLU A 1 33  ? 26.76953  -0.64399  14.18713  1.000 15.74681  ? 47  GLU A C    1 
ATOM   459  O O    . GLU A 1 33  ? 27.40472  -0.83519  15.23162  1.000 16.06194  ? 47  GLU A O    1 
ATOM   460  C CB   A GLU A 1 33  ? 27.98704  -0.66217  11.96554  0.462 20.33726  ? 47  GLU A CB   1 
ATOM   461  C CB   B GLU A 1 33  ? 27.96245  -0.60334  11.98146  0.538 19.43939  ? 47  GLU A CB   1 
ATOM   462  C CG   A GLU A 1 33  ? 28.58210  -1.55201  10.87736  0.462 24.16745  ? 47  GLU A CG   1 
ATOM   463  C CG   B GLU A 1 33  ? 29.26072  -0.08282  12.59641  0.538 22.94552  ? 47  GLU A CG   1 
ATOM   464  C CD   A GLU A 1 33  ? 28.93210  -0.80474  9.60177   0.462 27.28106  ? 47  GLU A CD   1 
ATOM   465  C CD   B GLU A 1 33  ? 30.04905  0.80580   11.64658  0.538 26.66862  ? 47  GLU A CD   1 
ATOM   466  O OE1  A GLU A 1 33  ? 29.25128  0.40193   9.67354   0.462 28.58710  ? 47  GLU A OE1  1 
ATOM   467  O OE1  B GLU A 1 33  ? 29.59675  1.00942   10.49926  0.538 28.07885  ? 47  GLU A OE1  1 
ATOM   468  O OE2  A GLU A 1 33  ? 28.88553  -1.43334  8.52337   0.462 28.25133  ? 47  GLU A OE2  1 
ATOM   469  O OE2  B GLU A 1 33  ? 31.12013  1.30543   12.05063  0.538 28.77400  ? 47  GLU A OE2  1 
ATOM   470  H H    . GLU A 1 33  ? 25.80166  -1.54695  11.43261  1.000 18.03535  ? 47  GLU A H    1 
ATOM   471  H HA   . GLU A 1 33  ? 27.58589  -2.22610  13.21373  1.000 19.91625  ? 47  GLU A HA   1 
ATOM   472  H HB2  A GLU A 1 33  ? 27.46258  0.03137   11.53560  0.462 24.39960  ? 47  GLU A HB2  1 
ATOM   473  H HB2  B GLU A 1 33  ? 28.20089  -1.15285  11.21852  0.538 23.32216  ? 47  GLU A HB2  1 
ATOM   474  H HB3  A GLU A 1 33  ? 28.71797  -0.26445  12.46400  0.462 24.39960  ? 47  GLU A HB3  1 
ATOM   475  H HB3  B GLU A 1 33  ? 27.44937  0.16606   11.68875  0.538 23.32216  ? 47  GLU A HB3  1 
ATOM   476  H HG2  A GLU A 1 33  ? 29.39575  -1.95760  11.21555  0.462 28.99583  ? 47  GLU A HG2  1 
ATOM   477  H HG2  B GLU A 1 33  ? 29.04918  0.43741   13.38730  0.538 27.52951  ? 47  GLU A HG2  1 
ATOM   478  H HG3  A GLU A 1 33  ? 27.93794  -2.24060  10.64977  0.462 28.99583  ? 47  GLU A HG3  1 
ATOM   479  H HG3  B GLU A 1 33  ? 29.82148  -0.83725  12.83576  0.538 27.52951  ? 47  GLU A HG3  1 
ATOM   480  N N    . GLU A 1 34  ? 25.78158  0.24505   14.11560  1.000 14.64021  ? 48  GLU A N    1 
ATOM   481  C CA   . GLU A 1 34  ? 25.41417  1.02953   15.28775  1.000 14.38957  ? 48  GLU A CA   1 
ATOM   482  C C    . GLU A 1 34  ? 24.77872  0.15873   16.36453  1.000 13.30709  ? 48  GLU A C    1 
ATOM   483  O O    . GLU A 1 34  ? 25.03982  0.35538   17.55831  1.000 13.70649  ? 48  GLU A O    1 
ATOM   484  C CB   . GLU A 1 34  ? 24.49187  2.17023   14.86648  1.000 15.12652  ? 48  GLU A CB   1 
ATOM   485  C CG   . GLU A 1 34  ? 25.22307  3.18496   14.01177  1.000 17.64859  ? 48  GLU A CG   1 
ATOM   486  C CD   . GLU A 1 34  ? 24.33063  4.21886   13.36614  1.000 20.86012  ? 48  GLU A CD   1 
ATOM   487  O OE1  . GLU A 1 34  ? 23.16966  3.92750   13.02602  1.000 20.45760  ? 48  GLU A OE1  1 
ATOM   488  O OE2  . GLU A 1 34  ? 24.82377  5.34314   13.16033  1.000 24.72313  ? 48  GLU A OE2  1 
ATOM   489  H H    . GLU A 1 34  ? 25.31607  0.41017   13.41158  1.000 17.56314  ? 48  GLU A H    1 
ATOM   490  H HA   . GLU A 1 34  ? 26.21105  1.42216   15.67726  0.935 17.26237  ? 48  GLU A HA   1 
ATOM   491  H HB2  . GLU A 1 34  ? 23.75269  1.81153   14.35087  1.000 18.14672  ? 48  GLU A HB2  1 
ATOM   492  H HB3  . GLU A 1 34  ? 24.15684  2.62083   15.65744  1.000 18.14672  ? 48  GLU A HB3  1 
ATOM   493  H HG2  . GLU A 1 34  ? 25.86138  3.65665   14.56941  1.000 21.17321  ? 48  GLU A HG2  1 
ATOM   494  H HG3  . GLU A 1 34  ? 25.68700  2.71446   13.30163  0.377 21.17321  ? 48  GLU A HG3  1 
ATOM   495  N N    . LEU A 1 35  ? 23.95431  -0.81151  15.96101  1.000 12.69529  ? 49  LEU A N    1 
ATOM   496  C CA   . LEU A 1 35  ? 23.36546  -1.73493  16.92018  1.000 12.16227  ? 49  LEU A CA   1 
ATOM   497  C C    . LEU A 1 35  ? 24.44820  -2.51815  17.64782  1.000 12.83881  ? 49  LEU A C    1 
ATOM   498  O O    . LEU A 1 35  ? 24.42098  -2.64800  18.87789  1.000 13.57679  ? 49  LEU A O    1 
ATOM   499  C CB   . LEU A 1 35  ? 22.41321  -2.68319  16.19856  1.000 12.29774  ? 49  LEU A CB   1 
ATOM   500  C CG   . LEU A 1 35  ? 21.13139  -2.03853  15.67753  1.000 12.57512  ? 49  LEU A CG   1 
ATOM   501  C CD1  . LEU A 1 35  ? 20.40478  -2.99347  14.77123  1.000 13.39876  ? 49  LEU A CD1  1 
ATOM   502  C CD2  . LEU A 1 35  ? 20.24609  -1.63318  16.83316  1.000 13.12395  ? 49  LEU A CD2  1 
ATOM   503  H H    . LEU A 1 35  ? 23.72431  -0.95216  15.14436  0.481 15.22924  ? 49  LEU A H    1 
ATOM   504  H HA   . LEU A 1 35  ? 22.85815  -1.23371  17.57768  1.000 14.58961  ? 49  LEU A HA   1 
ATOM   505  H HB2  . LEU A 1 35  ? 22.87846  -3.06342  15.43707  1.000 14.75218  ? 49  LEU A HB2  1 
ATOM   506  H HB3  . LEU A 1 35  ? 22.15587  -3.38645  16.81508  1.000 14.75218  ? 49  LEU A HB3  1 
ATOM   507  H HG   . LEU A 1 35  ? 21.35284  -1.24268  15.16912  1.000 15.08504  ? 49  LEU A HG   1 
ATOM   508  H HD11 . LEU A 1 35  ? 20.09965  -3.75282  15.29198  1.000 16.07340  ? 49  LEU A HD11 1 
ATOM   509  H HD12 . LEU A 1 35  ? 19.64571  -2.53744  14.37531  1.000 16.07340  ? 49  LEU A HD12 1 
ATOM   510  H HD13 . LEU A 1 35  ? 21.01118  -3.29179  14.07540  1.000 16.07340  ? 49  LEU A HD13 1 
ATOM   511  H HD21 . LEU A 1 35  ? 20.02961  -2.42068  17.35649  1.000 15.74364  ? 49  LEU A HD21 1 
ATOM   512  H HD22 . LEU A 1 35  ? 20.71994  -0.99022  17.38358  1.000 15.74364  ? 49  LEU A HD22 1 
ATOM   513  H HD23 . LEU A 1 35  ? 19.43369  -1.23451  16.48391  1.000 15.74364  ? 49  LEU A HD23 1 
ATOM   514  N N    . LEU A 1 36  ? 25.39522  -3.07090  16.89635  1.000 12.99476  ? 50  LEU A N    1 
ATOM   515  C CA   . LEU A 1 36  ? 26.50422  -3.79632  17.50663  1.000 13.77735  ? 50  LEU A CA   1 
ATOM   516  C C    . LEU A 1 36  ? 27.37453  -2.88755  18.36056  1.000 14.86239  ? 50  LEU A C    1 
ATOM   517  O O    . LEU A 1 36  ? 28.04633  -3.36352  19.28177  1.000 16.23354  ? 50  LEU A O    1 
ATOM   518  C CB   . LEU A 1 36  ? 27.34192  -4.44411  16.40869  1.000 14.38552  ? 50  LEU A CB   1 
ATOM   519  C CG   . LEU A 1 36  ? 26.68225  -5.60188  15.65659  1.000 14.48262  ? 50  LEU A CG   1 
ATOM   520  C CD1  . LEU A 1 36  ? 27.53674  -6.01306  14.48388  1.000 16.03510  ? 50  LEU A CD1  1 
ATOM   521  C CD2  . LEU A 1 36  ? 26.39010  -6.77715  16.57028  1.000 15.09268  ? 50  LEU A CD2  1 
ATOM   522  H H    . LEU A 1 36  ? 25.41948  -3.04103  16.03721  1.000 15.58860  ? 50  LEU A H    1 
ATOM   523  H HA   . LEU A 1 36  ? 26.15722  -4.49660  18.08118  0.890 16.52772  ? 50  LEU A HA   1 
ATOM   524  H HB2  . LEU A 1 36  ? 27.56014  -3.76313  15.75329  1.000 17.25752  ? 50  LEU A HB2  1 
ATOM   525  H HB3  . LEU A 1 36  ? 28.15402  -4.78905  16.81169  1.000 17.25752  ? 50  LEU A HB3  1 
ATOM   526  H HG   . LEU A 1 36  ? 25.82478  -5.30212  15.31633  0.757 17.37403  ? 50  LEU A HG   1 
ATOM   527  H HD11 . LEU A 1 36  ? 27.15388  -6.80590  14.07678  0.399 19.23701  ? 50  LEU A HD11 1 
ATOM   528  H HD12 . LEU A 1 36  ? 27.55877  -5.28822  13.83966  1.000 19.23701  ? 50  LEU A HD12 1 
ATOM   529  H HD13 . LEU A 1 36  ? 28.43434  -6.20337  14.79851  0.951 19.23701  ? 50  LEU A HD13 1 
ATOM   530  H HD21 . LEU A 1 36  ? 25.94813  -7.47269  16.05864  1.000 18.10610  ? 50  LEU A HD21 1 
ATOM   531  H HD22 . LEU A 1 36  ? 27.22593  -7.11222  16.93088  1.000 18.10610  ? 50  LEU A HD22 1 
ATOM   532  H HD23 . LEU A 1 36  ? 25.81381  -6.48050  17.29194  1.000 18.10610  ? 50  LEU A HD23 1 
ATOM   533  N N    . GLY A 1 37  ? 27.37749  -1.59429  18.07474  1.000 14.93168  ? 51  GLY A N    1 
ATOM   534  C CA   . GLY A 1 37  ? 28.15735  -0.59918  18.77439  1.000 15.89267  ? 51  GLY A CA   1 
ATOM   535  C C    . GLY A 1 37  ? 27.49607  -0.00555  19.99529  1.000 16.06405  ? 51  GLY A C    1 
ATOM   536  O O    . GLY A 1 37  ? 27.99813  0.98773   20.51976  1.000 18.35380  ? 51  GLY A O    1 
ATOM   537  H H    . GLY A 1 37  ? 26.90630  -1.25335  17.44122  1.000 17.91290  ? 51  GLY A H    1 
ATOM   538  H HA2  . GLY A 1 37  ? 28.99155  -1.00413  19.05903  1.000 19.06610  ? 51  GLY A HA2  1 
ATOM   539  H HA3  . GLY A 1 37  ? 28.35186  0.12769   18.16224  0.109 19.06610  ? 51  GLY A HA3  1 
ATOM   540  N N    . GLY A 1 38  ? 26.38475  -0.55797  20.45946  1.000 14.99907  ? 52  GLY A N    1 
ATOM   541  C CA   . GLY A 1 38  ? 25.78155  -0.11937  21.69152  1.000 14.77261  ? 52  GLY A CA   1 
ATOM   542  C C    . GLY A 1 38  ? 24.67479  0.89973   21.57320  1.000 13.36384  ? 52  GLY A C    1 
ATOM   543  O O    . GLY A 1 38  ? 24.32926  1.51802   22.57986  1.000 13.76262  ? 52  GLY A O    1 
ATOM   544  H H    . GLY A 1 38  ? 25.96096  -1.19627  20.06885  1.000 17.99378  ? 52  GLY A H    1 
ATOM   545  H HA2  . GLY A 1 38  ? 25.41313  -0.89503  22.14265  0.720 17.72202  ? 52  GLY A HA2  1 
ATOM   546  H HA3  . GLY A 1 38  ? 26.47451  0.26983   22.24761  1.000 17.72202  ? 52  GLY A HA3  1 
ATOM   547  N N    . TYR A 1 39  ? 24.07880  1.06247   20.40056  1.000 12.75817  ? 53  TYR A N    1 
ATOM   548  C CA   . TYR A 1 39  ? 22.91553  1.92820   20.28249  1.000 12.21363  ? 53  TYR A CA   1 
ATOM   549  C C    . TYR A 1 39  ? 21.87351  1.51339   21.31038  1.000 11.56361  ? 53  TYR A C    1 
ATOM   550  O O    . TYR A 1 39  ? 21.59552  0.32215   21.48887  1.000 12.02195  ? 53  TYR A O    1 
ATOM   551  C CB   . TYR A 1 39  ? 22.34039  1.77701   18.88398  1.000 13.31240  ? 53  TYR A CB   1 
ATOM   552  C CG   . TYR A 1 39  ? 21.05044  2.50715   18.63339  1.000 13.20872  ? 53  TYR A CG   1 
ATOM   553  C CD1  . TYR A 1 39  ? 19.83155  1.89941   18.88568  1.000 13.51397  ? 53  TYR A CD1  1 
ATOM   554  C CD2  . TYR A 1 39  ? 21.04818  3.78586   18.07541  1.000 13.43101  ? 53  TYR A CD2  1 
ATOM   555  C CE1  . TYR A 1 39  ? 18.65433  2.53869   18.61939  1.000 13.38847  ? 53  TYR A CE1  1 
ATOM   556  C CE2  . TYR A 1 39  ? 19.86368  4.43858   17.81215  1.000 13.30396  ? 53  TYR A CE2  1 
ATOM   557  C CZ   . TYR A 1 39  ? 18.66344  3.79855   18.06612  1.000 13.07734  ? 53  TYR A CZ   1 
ATOM   558  O OH   . TYR A 1 39  ? 17.45417  4.38962   17.78921  1.000 13.69001  ? 53  TYR A OH   1 
ATOM   559  H H    . TYR A 1 39  ? 24.32496  0.68769   19.66671  1.000 15.30470  ? 53  TYR A H    1 
ATOM   560  H HA   . TYR A 1 39  ? 23.15561  2.85614   20.43139  1.000 14.65125  ? 53  TYR A HA   1 
ATOM   561  H HB2  . TYR A 1 39  ? 22.99107  2.11379   18.24829  1.000 15.96977  ? 53  TYR A HB2  1 
ATOM   562  H HB3  . TYR A 1 39  ? 22.17521  0.83499   18.72206  1.000 15.96977  ? 53  TYR A HB3  1 
ATOM   563  H HD1  . TYR A 1 39  ? 19.81447  1.04085   19.24273  0.494 16.21166  ? 53  TYR A HD1  1 
ATOM   564  H HD2  . TYR A 1 39  ? 21.85594  4.20270   17.87879  1.000 16.11210  ? 53  TYR A HD2  1 
ATOM   565  H HE1  . TYR A 1 39  ? 17.84559  2.12198   18.81223  0.772 16.06106  ? 53  TYR A HE1  1 
ATOM   566  H HE2  . TYR A 1 39  ? 19.87078  5.30200   17.46668  0.993 15.95965  ? 53  TYR A HE2  1 
ATOM   567  H HH   . TYR A 1 39  ? 17.57627  5.14462   17.44185  0.956 16.42291  ? 53  TYR A HH   1 
ATOM   568  N N    . VAL A 1 40  ? 21.27423  2.50429   21.96827  1.000 11.48031  ? 54  VAL A N    1 
ATOM   569  C CA   . VAL A 1 40  ? 20.29131  2.23455   23.01084  1.000 11.79470  ? 54  VAL A CA   1 
ATOM   570  C C    . VAL A 1 40  ? 19.40709  3.46112   23.16703  1.000 11.66142  ? 54  VAL A C    1 
ATOM   571  O O    . VAL A 1 40  ? 19.87847  4.59238   23.08936  1.000 12.46308  ? 54  VAL A O    1 
ATOM   572  C CB   . VAL A 1 40  ? 20.98997  1.85898   24.34224  1.000 12.68606  ? 54  VAL A CB   1 
ATOM   573  C CG1  . VAL A 1 40  ? 21.86276  3.00744   24.86984  1.000 14.23063  ? 54  VAL A CG1  1 
ATOM   574  C CG2  . VAL A 1 40  ? 19.97394  1.41771   25.38174  1.000 12.97362  ? 54  VAL A CG2  1 
ATOM   575  H H    . VAL A 1 40  ? 21.42091  3.33999   21.82798  1.000 13.77127  ? 54  VAL A H    1 
ATOM   576  H HA   . VAL A 1 40  ? 19.72892  1.49403   22.73470  0.550 14.14854  ? 54  VAL A HA   1 
ATOM   577  H HB   . VAL A 1 40  ? 21.58187  1.11043   24.16840  1.000 15.21816  ? 54  VAL A HB   1 
ATOM   578  H HG11 . VAL A 1 40  ? 22.35691  2.69809   25.64509  0.550 17.07164  ? 54  VAL A HG11 1 
ATOM   579  H HG12 . VAL A 1 40  ? 22.47890  3.28180   24.17271  1.000 17.07164  ? 54  VAL A HG12 1 
ATOM   580  H HG13 . VAL A 1 40  ? 21.29082  3.75082   25.11716  1.000 17.07164  ? 54  VAL A HG13 1 
ATOM   581  H HG21 . VAL A 1 40  ? 19.28801  0.88687   24.94745  0.858 15.56324  ? 54  VAL A HG21 1 
ATOM   582  H HG22 . VAL A 1 40  ? 20.42392  0.88747   26.05796  0.588 15.56324  ? 54  VAL A HG22 1 
ATOM   583  H HG23 . VAL A 1 40  ? 19.57624  2.20358   25.78811  1.000 15.56324  ? 54  VAL A HG23 1 
ATOM   584  N N    . GLY A 1 41  ? 18.12480  3.22343   23.41463  1.000 11.38915  ? 55  GLY A N    1 
ATOM   585  C CA   . GLY A 1 41  ? 17.19278  4.27170   23.78806  1.000 12.28900  ? 55  GLY A CA   1 
ATOM   586  C C    . GLY A 1 41  ? 16.00380  3.62040   24.45876  1.000 11.79311  ? 55  GLY A C    1 
ATOM   587  O O    . GLY A 1 41  ? 15.90550  2.39564   24.51407  1.000 11.73262  ? 55  GLY A O    1 
ATOM   588  H H    . GLY A 1 41  ? 17.76316  2.44434   23.37162  0.796 13.66188  ? 55  GLY A H    1 
ATOM   589  H HA2  . GLY A 1 41  ? 17.61139  4.89363   24.40358  1.000 14.74170  ? 55  GLY A HA2  1 
ATOM   590  H HA3  . GLY A 1 41  ? 16.89590  4.75670   23.00223  1.000 14.74170  ? 55  GLY A HA3  1 
ATOM   591  N N    . SER A 1 42  ? 15.07028  4.43890   24.95660  1.000 12.10652  ? 56  SER A N    1 
ATOM   592  C CA   A SER A 1 42  ? 13.89700  3.87230   25.61540  0.775 12.86939  ? 56  SER A CA   1 
ATOM   593  C CA   B SER A 1 42  ? 13.89274  3.87659   25.61350  0.225 12.68830  ? 56  SER A CA   1 
ATOM   594  C C    . SER A 1 42  ? 13.13841  2.92656   24.69438  1.000 11.95542  ? 56  SER A C    1 
ATOM   595  O O    . SER A 1 42  ? 12.48058  1.99523   25.16814  1.000 12.27478  ? 56  SER A O    1 
ATOM   596  C CB   A SER A 1 42  ? 12.97605  4.97139   26.12063  0.775 14.95656  ? 56  SER A CB   1 
ATOM   597  C CB   B SER A 1 42  ? 12.95795  4.99250   26.07607  0.225 14.14489  ? 56  SER A CB   1 
ATOM   598  O OG   A SER A 1 42  ? 12.48765  5.73380   25.04556  0.775 15.84154  ? 56  SER A OG   1 
ATOM   599  O OG   B SER A 1 42  ? 13.60011  5.85333   26.99718  0.225 15.12851  ? 56  SER A OG   1 
ATOM   600  H H    . SER A 1 42  ? 15.09102  5.29815   24.92733  1.000 14.52272  ? 56  SER A H    1 
ATOM   601  H HA   . SER A 1 42  ? 14.19734  3.36747   26.38731  0.455 15.22086  ? 56  SER A HA   1 
ATOM   602  H HB2  A SER A 1 42  ? 12.22863  4.56872   26.58980  0.775 17.94276  ? 56  SER A HB2  1 
ATOM   603  H HB2  B SER A 1 42  ? 12.68075  5.50989   25.30382  0.225 16.96876  ? 56  SER A HB2  1 
ATOM   604  H HB3  A SER A 1 42  ? 13.47171  5.55002   26.72098  0.775 17.94276  ? 56  SER A HB3  1 
ATOM   605  H HB3  B SER A 1 42  ? 12.18364  4.59562   26.50482  0.225 16.96876  ? 56  SER A HB3  1 
ATOM   606  H HG   A SER A 1 42  ? 13.12778  6.03335   24.59157  0.775 19.00473  ? 56  SER A HG   1 
ATOM   607  H HG   B SER A 1 42  ? 14.00904  5.40170   27.57546  0.225 18.14910  ? 56  SER A HG   1 
ATOM   608  N N    . GLN A 1 43  ? 13.23248  3.14088   23.38635  1.000 11.51770  ? 57  GLN A N    1 
ATOM   609  C CA   . GLN A 1 43  ? 12.51886  2.32228   22.41895  1.000 11.53738  ? 57  GLN A CA   1 
ATOM   610  C C    . GLN A 1 43  ? 13.16558  0.96135   22.20071  1.000 11.26418  ? 57  GLN A C    1 
ATOM   611  O O    . GLN A 1 43  ? 12.52238  0.07179   21.62793  1.000 11.48497  ? 57  GLN A O    1 
ATOM   612  C CB   . GLN A 1 43  ? 12.41407  3.06639   21.08115  1.000 11.99797  ? 57  GLN A CB   1 
ATOM   613  C CG   . GLN A 1 43  ? 13.72692  3.21270   20.29467  1.000 11.80650  ? 57  GLN A CG   1 
ATOM   614  C CD   . GLN A 1 43  ? 14.64385  4.32808   20.75191  1.000 11.69961  ? 57  GLN A CD   1 
ATOM   615  O OE1  . GLN A 1 43  ? 14.43362  4.96985   21.78451  1.000 12.93338  ? 57  GLN A OE1  1 
ATOM   616  N NE2  . GLN A 1 43  ? 15.68016  4.56223   19.97018  1.000 12.40228  ? 57  GLN A NE2  1 
ATOM   617  H H    . GLN A 1 43  ? 13.70919  3.76199   23.03059  0.923 13.81613  ? 57  GLN A H    1 
ATOM   618  H HA   . GLN A 1 43  ? 11.61969  2.16756   22.74827  1.000 13.83975  ? 57  GLN A HA   1 
ATOM   619  H HB2  . GLN A 1 43  ? 11.79083  2.58607   20.51392  1.000 14.39245  ? 57  GLN A HB2  1 
ATOM   620  H HB3  . GLN A 1 43  ? 12.08206  3.96091   21.25583  1.000 14.39245  ? 57  GLN A HB3  1 
ATOM   621  H HG2  . GLN A 1 43  ? 14.22291  2.38269   20.37208  1.000 14.16269  ? 57  GLN A HG2  1 
ATOM   622  H HG3  . GLN A 1 43  ? 13.50820  3.38303   19.36513  1.000 14.16269  ? 57  GLN A HG3  1 
ATOM   623  H HE21 . GLN A 1 43  ? 15.79590  4.09436   19.25792  1.000 14.87763  ? 57  GLN A HE21 1 
ATOM   624  H HE22 . GLN A 1 43  ? 16.24009  5.18275   20.17275  1.000 14.87763  ? 57  GLN A HE22 1 
ATOM   625  N N    . PHE A 1 44  ? 14.42102  0.78057   22.62107  1.000 11.08485  ? 58  PHE A N    1 
ATOM   626  C CA   . PHE A 1 44  ? 15.19307  -0.40658  22.24665  1.000 10.82147  ? 58  PHE A CA   1 
ATOM   627  C C    . PHE A 1 44  ? 16.31986  -0.54740  23.26840  1.000 10.83612  ? 58  PHE A C    1 
ATOM   628  O O    . PHE A 1 44  ? 17.35897  0.10332   23.13617  1.000 10.84134  ? 58  PHE A O    1 
ATOM   629  C CB   . PHE A 1 44  ? 15.74758  -0.25213  20.83815  1.000 11.08821  ? 58  PHE A CB   1 
ATOM   630  C CG   . PHE A 1 44  ? 16.53311  -1.43706  20.36521  1.000 11.10632  ? 58  PHE A CG   1 
ATOM   631  C CD1  . PHE A 1 44  ? 15.89290  -2.60370  19.96955  1.000 11.36742  ? 58  PHE A CD1  1 
ATOM   632  C CD2  . PHE A 1 44  ? 17.92025  -1.40090  20.35613  1.000 11.41868  ? 58  PHE A CD2  1 
ATOM   633  C CE1  . PHE A 1 44  ? 16.61863  -3.69514  19.54328  1.000 12.03064  ? 58  PHE A CE1  1 
ATOM   634  C CE2  . PHE A 1 44  ? 18.65305  -2.49525  19.94402  1.000 11.90800  ? 58  PHE A CE2  1 
ATOM   635  C CZ   . PHE A 1 44  ? 18.00714  -3.63659  19.53079  1.000 12.10700  ? 58  PHE A CZ   1 
ATOM   636  H H    . PHE A 1 44  ? 14.84849  1.33145   23.12446  1.000 13.29671  ? 58  PHE A H    1 
ATOM   637  H HA   . PHE A 1 44  ? 14.63174  -1.19669  22.28580  1.000 12.98066  ? 58  PHE A HA   1 
ATOM   638  H HB2  . PHE A 1 44  ? 15.00779  -0.12322  20.22415  1.000 13.30074  ? 58  PHE A HB2  1 
ATOM   639  H HB3  . PHE A 1 44  ? 16.33462  0.51977   20.81701  1.000 13.30074  ? 58  PHE A HB3  1 
ATOM   640  H HD1  . PHE A 1 44  ? 14.96429  -2.64923  19.99239  1.000 13.63580  ? 58  PHE A HD1  1 
ATOM   641  H HD2  . PHE A 1 44  ? 18.36145  -0.62979  20.63113  1.000 13.69731  ? 58  PHE A HD2  1 
ATOM   642  H HE1  . PHE A 1 44  ? 16.18117  -4.46730  19.26526  1.000 14.43166  ? 58  PHE A HE1  1 
ATOM   643  H HE2  . PHE A 1 44  ? 19.58241  -2.46083  19.94579  1.000 14.28450  ? 58  PHE A HE2  1 
ATOM   644  H HZ   . PHE A 1 44  ? 18.50019  -4.37053  19.24249  1.000 14.52330  ? 58  PHE A HZ   1 
ATOM   645  N N    . TYR A 1 45  ? 16.10838  -1.38674  24.28537  1.000 10.61809  ? 59  TYR A N    1 
ATOM   646  C CA   . TYR A 1 45  ? 17.11576  -1.55246  25.32283  1.000 10.86251  ? 59  TYR A CA   1 
ATOM   647  C C    . TYR A 1 45  ? 17.00836  -2.94846  25.90085  1.000 11.03002  ? 59  TYR A C    1 
ATOM   648  O O    . TYR A 1 45  ? 16.04614  -3.67919  25.64316  1.000 11.24057  ? 59  TYR A O    1 
ATOM   649  C CB   . TYR A 1 45  ? 17.02493  -0.46919  26.39154  1.000 12.24787  ? 59  TYR A CB   1 
ATOM   650  C CG   . TYR A 1 45  ? 15.80266  -0.45193  27.28053  1.000 12.49230  ? 59  TYR A CG   1 
ATOM   651  C CD1  . TYR A 1 45  ? 15.71912  -1.25292  28.41447  1.000 14.10104  ? 59  TYR A CD1  1 
ATOM   652  C CD2  . TYR A 1 45  ? 14.77099  0.45198   27.04856  1.000 13.63538  ? 59  TYR A CD2  1 
ATOM   653  C CE1  . TYR A 1 45  ? 14.62382  -1.18724  29.26771  1.000 15.23449  ? 59  TYR A CE1  1 
ATOM   654  C CE2  . TYR A 1 45  ? 13.67952  0.53083   27.89848  1.000 14.57534  ? 59  TYR A CE2  1 
ATOM   655  C CZ   . TYR A 1 45  ? 13.60936  -0.28600  29.00721  1.000 15.26025  ? 59  TYR A CZ   1 
ATOM   656  O OH   . TYR A 1 45  ? 12.52130  -0.19631  29.85300  1.000 17.52488  ? 59  TYR A OH   1 
ATOM   657  H H    . TYR A 1 45  ? 15.39930  -1.86177  24.39090  0.784 12.73661  ? 59  TYR A H    1 
ATOM   658  H HA   . TYR A 1 45  ? 17.99621  -1.47610  24.92299  1.000 13.02991  ? 59  TYR A HA   1 
ATOM   659  H HB2  . TYR A 1 45  ? 17.79269  -0.56601  26.97640  1.000 14.69234  ? 59  TYR A HB2  1 
ATOM   660  H HB3  . TYR A 1 45  ? 17.05523  0.39080   25.94388  1.000 14.69234  ? 59  TYR A HB3  1 
ATOM   661  H HD1  . TYR A 1 45  ? 16.41049  -1.84478  28.60580  0.497 16.91614  ? 59  TYR A HD1  1 
ATOM   662  H HD2  . TYR A 1 45  ? 14.81470  1.01406   26.30892  0.916 16.35735  ? 59  TYR A HD2  1 
ATOM   663  H HE1  . TYR A 1 45  ? 14.57409  -1.74633  30.00922  1.000 18.27628  ? 59  TYR A HE1  1 
ATOM   664  H HE2  . TYR A 1 45  ? 12.99455  1.13440   27.72125  0.580 17.48530  ? 59  TYR A HE2  1 
ATOM   665  H HH   . TYR A 1 45  ? 12.62820  -0.70416  30.51350  1.000 21.02475  ? 59  TYR A HH   1 
ATOM   666  N N    . LEU A 1 46  ? 18.01629  -3.29655  26.70087  1.000 11.40957  ? 60  LEU A N    1 
ATOM   667  C CA   . LEU A 1 46  ? 18.09485  -4.59313  27.35699  1.000 11.74186  ? 60  LEU A CA   1 
ATOM   668  C C    . LEU A 1 46  ? 17.39015  -4.48915  28.69761  1.000 12.03272  ? 60  LEU A C    1 
ATOM   669  O O    . LEU A 1 46  ? 17.82854  -3.75208  29.58341  1.000 13.35313  ? 60  LEU A O    1 
ATOM   670  C CB   . LEU A 1 46  ? 19.54771  -5.00572  27.52945  1.000 11.94042  ? 60  LEU A CB   1 
ATOM   671  C CG   . LEU A 1 46  ? 19.74830  -6.46295  27.95492  1.000 12.70622  ? 60  LEU A CG   1 
ATOM   672  C CD1  . LEU A 1 46  ? 19.42766  -7.41187  26.82063  1.000 13.78467  ? 60  LEU A CD1  1 
ATOM   673  C CD2  . LEU A 1 46  ? 21.16747  -6.68614  28.45146  1.000 13.98968  ? 60  LEU A CD2  1 
ATOM   674  H H    . LEU A 1 46  ? 18.68196  -2.78285  26.88143  1.000 13.68637  ? 60  LEU A H    1 
ATOM   675  H HA   . LEU A 1 46  ? 17.64556  -5.26580  26.82169  1.000 14.08512  ? 60  LEU A HA   1 
ATOM   676  H HB2  . LEU A 1 46  ? 20.00594  -4.88115  26.68364  1.000 14.32340  ? 60  LEU A HB2  1 
ATOM   677  H HB3  . LEU A 1 46  ? 19.94908  -4.44326  28.21021  1.000 14.32340  ? 60  LEU A HB3  1 
ATOM   678  H HG   . LEU A 1 46  ? 19.13797  -6.65701  28.68345  1.000 15.24236  ? 60  LEU A HG   1 
ATOM   679  H HD11 . LEU A 1 46  ? 19.98241  -7.18964  26.05659  1.000 16.53649  ? 60  LEU A HD11 1 
ATOM   680  H HD12 . LEU A 1 46  ? 19.60909  -8.32037  27.10807  0.335 16.53649  ? 60  LEU A HD12 1 
ATOM   681  H HD13 . LEU A 1 46  ? 18.49071  -7.31971  26.58709  1.000 16.53649  ? 60  LEU A HD13 1 
ATOM   682  H HD21 . LEU A 1 46  ? 21.78831  -6.48682  27.73332  1.000 16.78251  ? 60  LEU A HD21 1 
ATOM   683  H HD22 . LEU A 1 46  ? 21.33425  -6.09905  29.20539  0.628 16.78251  ? 60  LEU A HD22 1 
ATOM   684  H HD23 . LEU A 1 46  ? 21.26439  -7.61166  28.72516  1.000 16.78251  ? 60  LEU A HD23 1 
ATOM   685  N N    . GLN A 1 47  ? 16.28183  -5.19819  28.83229  1.000 12.09458  ? 61  GLN A N    1 
ATOM   686  C CA   . GLN A 1 47  ? 15.46202  -5.17835  30.02849  1.000 12.66274  ? 61  GLN A CA   1 
ATOM   687  C C    . GLN A 1 47  ? 15.76183  -6.40195  30.89443  1.000 13.31883  ? 61  GLN A C    1 
ATOM   688  O O    . GLN A 1 47  ? 15.91809  -7.52124  30.39226  1.000 12.96723  ? 61  GLN A O    1 
ATOM   689  C CB   . GLN A 1 47  ? 13.98570  -5.14438  29.61508  1.000 13.51680  ? 61  GLN A CB   1 
ATOM   690  C CG   . GLN A 1 47  ? 13.01968  -4.78271  30.72654  1.000 14.65945  ? 61  GLN A CG   1 
ATOM   691  C CD   . GLN A 1 47  ? 12.60467  -5.97248  31.55272  1.000 14.54666  ? 61  GLN A CD   1 
ATOM   692  O OE1  . GLN A 1 47  ? 12.60812  -7.10400  31.07384  1.000 14.93429  ? 61  GLN A OE1  1 
ATOM   693  N NE2  . GLN A 1 47  ? 12.23038  -5.72793  32.80218  1.000 16.38113  ? 61  GLN A NE2  1 
ATOM   694  H H    . GLN A 1 47  ? 15.97307  -5.71795  28.22064  1.000 14.50838  ? 61  GLN A H    1 
ATOM   695  H HA   . GLN A 1 47  ? 15.65560  -4.39809  30.57128  1.000 15.19017  ? 61  GLN A HA   1 
ATOM   696  H HB2  . GLN A 1 47  ? 13.87884  -4.48616  28.91065  1.000 16.21506  ? 61  GLN A HB2  1 
ATOM   697  H HB3  . GLN A 1 47  ? 13.73774  -6.02335  29.28822  1.000 16.21506  ? 61  GLN A HB3  1 
ATOM   698  H HG2  . GLN A 1 47  ? 13.44436  -4.14137  31.31749  1.000 17.58623  ? 61  GLN A HG2  1 
ATOM   699  H HG3  . GLN A 1 47  ? 12.22035  -4.39571  30.33640  1.000 17.58623  ? 61  GLN A HG3  1 
ATOM   700  H HE21 . GLN A 1 47  ? 12.23321  -4.92188  33.10196  1.000 19.65225  ? 61  GLN A HE21 1 
ATOM   701  H HE22 . GLN A 1 47  ? 11.98499  -6.37550  33.31211  0.630 19.65225  ? 61  GLN A HE22 1 
ATOM   702  N N    . ASP A 1 48  ? 15.87902  -6.17021  32.20472  1.000 14.54011  ? 62  ASP A N    1 
ATOM   703  C CA   . ASP A 1 48  ? 16.15169  -7.22838  33.17858  1.000 16.04154  ? 62  ASP A CA   1 
ATOM   704  C C    . ASP A 1 48  ? 17.39121  -8.04709  32.81698  1.000 15.59641  ? 62  ASP A C    1 
ATOM   705  O O    . ASP A 1 48  ? 17.47302  -9.24099  33.11120  1.000 17.23720  ? 62  ASP A O    1 
ATOM   706  C CB   . ASP A 1 48  ? 14.93769  -8.13212  33.40148  1.000 19.27773  ? 62  ASP A CB   1 
ATOM   707  C CG   . ASP A 1 48  ? 15.00095  -8.87277  34.73883  1.000 24.11369  ? 62  ASP A CG   1 
ATOM   708  O OD1  . ASP A 1 48  ? 15.62696  -8.35632  35.69006  1.000 23.66678  ? 62  ASP A OD1  1 
ATOM   709  O OD2  . ASP A 1 48  ? 14.43311  -9.98263  34.83237  1.000 29.24915  ? 62  ASP A OD2  1 
ATOM   710  H H    . ASP A 1 48  ? 15.80294  -5.39127  32.56118  1.000 17.44303  ? 62  ASP A H    1 
ATOM   711  H HA   . ASP A 1 48  ? 16.34331  -6.79284  34.02386  0.667 19.24474  ? 62  ASP A HA   1 
ATOM   712  H HB2  . ASP A 1 48  ? 14.13300  -7.59052  33.39444  0.424 23.12816  ? 62  ASP A HB2  1 
ATOM   713  H HB3  . ASP A 1 48  ? 14.89912  -8.79282  32.69234  1.000 23.12816  ? 62  ASP A HB3  1 
ATOM   714  N N    . GLY A 1 49  ? 18.36891  -7.42154  32.16881  1.000 15.39528  ? 63  GLY A N    1 
ATOM   715  C CA   . GLY A 1 49  ? 19.61224  -8.09307  31.84441  1.000 15.52169  ? 63  GLY A CA   1 
ATOM   716  C C    . GLY A 1 49  ? 19.53518  -9.12937  30.75001  1.000 15.32871  ? 63  GLY A C    1 
ATOM   717  O O    . GLY A 1 49  ? 20.56235  -9.74452  30.44151  1.000 17.04161  ? 63  GLY A O    1 
ATOM   718  H H    . GLY A 1 49  ? 18.33196  -6.60336  31.90646  1.000 18.46923  ? 63  GLY A H    1 
ATOM   719  H HA2  . GLY A 1 49  ? 20.25846  -7.42463  31.56787  1.000 18.62092  ? 63  GLY A HA2  1 
ATOM   720  H HA3  . GLY A 1 49  ? 19.93854  -8.53636  32.64311  1.000 18.62092  ? 63  GLY A HA3  1 
ATOM   721  N N    . LYS A 1 50  ? 18.37420  -9.34238  30.12934  1.000 14.02913  ? 64  LYS A N    1 
ATOM   722  C CA   . LYS A 1 50  ? 18.29288  -10.45817 29.19582  1.000 15.03023  ? 64  LYS A CA   1 
ATOM   723  C C    . LYS A 1 50  ? 17.30649  -10.27631 28.05951  1.000 13.39100  ? 64  LYS A C    1 
ATOM   724  O O    . LYS A 1 50  ? 17.37558  -11.04482 27.11237  1.000 14.54738  ? 64  LYS A O    1 
ATOM   725  C CB   . LYS A 1 50  ? 18.00933  -11.75933 29.93716  1.000 17.95279  ? 64  LYS A CB   1 
ATOM   726  C CG   . LYS A 1 50  ? 16.64238  -11.84362 30.54560  1.000 20.28913  ? 64  LYS A CG   1 
ATOM   727  C CD   . LYS A 1 50  ? 16.65636  -12.93937 31.60254  1.000 25.15649  ? 64  LYS A CD   1 
ATOM   728  C CE   . LYS A 1 50  ? 15.29414  -13.53053 31.85486  1.000 28.63949  ? 64  LYS A CE   1 
ATOM   729  N NZ   . LYS A 1 50  ? 15.34740  -14.47596 33.00817  1.000 31.05388  ? 64  LYS A NZ   1 
ATOM   730  H H    . LYS A 1 50  ? 17.65774  -8.87717  30.22871  1.000 16.82985  ? 64  LYS A H    1 
ATOM   731  H HA   . LYS A 1 50  ? 19.16235  -10.50760 28.76864  1.000 18.03117  ? 64  LYS A HA   1 
ATOM   732  H HB2  . LYS A 1 50  ? 18.09779  -12.49618 29.31255  1.000 21.53825  ? 64  LYS A HB2  1 
ATOM   733  H HB3  . LYS A 1 50  ? 18.65546  -11.85313 30.65452  1.000 21.53825  ? 64  LYS A HB3  1 
ATOM   734  H HG2  . LYS A 1 50  ? 16.41148  -10.99996 30.96492  1.000 24.34185  ? 64  LYS A HG2  1 
ATOM   735  H HG3  . LYS A 1 50  ? 15.98774  -12.06608 29.86526  1.000 24.34185  ? 64  LYS A HG3  1 
ATOM   736  H HD2  . LYS A 1 50  ? 17.24223  -13.65427 31.30831  1.000 30.18268  ? 64  LYS A HD2  1 
ATOM   737  H HD3  . LYS A 1 50  ? 16.98003  -12.56786 32.43808  1.000 30.18268  ? 64  LYS A HD3  1 
ATOM   738  H HE2  . LYS A 1 50  ? 14.66492  -12.82224 32.06299  1.000 34.36228  ? 64  LYS A HE2  1 
ATOM   739  H HE3  . LYS A 1 50  ? 14.99890  -14.01618 31.06881  1.000 34.36228  ? 64  LYS A HE3  1 
ATOM   740  H HZ1  . LYS A 1 50  ? 14.95733  -14.11040 33.71972  1.000 37.25955  ? 64  LYS A HZ1  1 
ATOM   741  H HZ2  . LYS A 1 50  ? 14.92364  -15.23111 32.80255  1.000 37.25955  ? 64  LYS A HZ2  1 
ATOM   742  H HZ3  . LYS A 1 50  ? 16.19383  -14.66495 33.20801  1.000 37.25955  ? 64  LYS A HZ3  1 
ATOM   743  N N    . TYR A 1 51  ? 16.41196  -9.29907  28.10984  1.000 11.73364  ? 65  TYR A N    1 
ATOM   744  C CA   . TYR A 1 51  ? 15.38652  -9.15926  27.08230  1.000 11.51733  ? 65  TYR A CA   1 
ATOM   745  C C    . TYR A 1 51  ? 15.68430  -7.98149  26.16784  1.000 11.31859  ? 65  TYR A C    1 
ATOM   746  O O    . TYR A 1 51  ? 15.87391  -6.85259  26.63339  1.000 12.25786  ? 65  TYR A O    1 
ATOM   747  C CB   . TYR A 1 51  ? 14.00535  -8.95513  27.69336  1.000 12.45198  ? 65  TYR A CB   1 
ATOM   748  C CG   . TYR A 1 51  ? 13.50748  -10.09100 28.54684  1.000 13.46695  ? 65  TYR A CG   1 
ATOM   749  C CD1  . TYR A 1 51  ? 13.09087  -11.28915 27.98338  1.000 14.33998  ? 65  TYR A CD1  1 
ATOM   750  C CD2  . TYR A 1 51  ? 13.40934  -9.94756  29.92971  1.000 14.26584  ? 65  TYR A CD2  1 
ATOM   751  C CE1  . TYR A 1 51  ? 12.61880  -12.32216 28.77403  1.000 15.57432  ? 65  TYR A CE1  1 
ATOM   752  C CE2  . TYR A 1 51  ? 12.93131  -10.96596 30.72059  1.000 15.40183  ? 65  TYR A CE2  1 
ATOM   753  C CZ   . TYR A 1 51  ? 12.54421  -12.15902 30.14244  1.000 16.00885  ? 65  TYR A CZ   1 
ATOM   754  O OH   . TYR A 1 51  ? 12.06584  -13.17743 30.93634  1.000 18.90004  ? 65  TYR A OH   1 
ATOM   755  H H    . TYR A 1 51  ? 16.37791  -8.70374  28.72953  1.000 14.07525  ? 65  TYR A H    1 
ATOM   756  H HA   . TYR A 1 51  ? 15.39473  -9.97279  26.55410  1.000 13.81569  ? 65  TYR A HA   1 
ATOM   757  H HB2  . TYR A 1 51  ? 14.03180  -8.16269  28.25214  1.000 14.93726  ? 65  TYR A HB2  1 
ATOM   758  H HB3  . TYR A 1 51  ? 13.36709  -8.83220  26.97334  1.000 14.93726  ? 65  TYR A HB3  1 
ATOM   759  H HD1  . TYR A 1 51  ? 13.12956  -11.39937 27.06075  0.476 17.20287  ? 65  TYR A HD1  1 
ATOM   760  H HD2  . TYR A 1 51  ? 13.67215  -9.14789  30.32514  1.000 17.11390  ? 65  TYR A HD2  1 
ATOM   761  H HE1  . TYR A 1 51  ? 12.35270  -13.12365 28.38455  1.000 18.68407  ? 65  TYR A HE1  1 
ATOM   762  H HE2  . TYR A 1 51  ? 12.86891  -10.85171 31.64144  0.413 18.47709  ? 65  TYR A HE2  1 
ATOM   763  H HH   . TYR A 1 51  ? 12.11278  -12.95712 31.74557  0.452 22.67494  ? 65  TYR A HH   1 
ATOM   764  N N    . MET A 1 52  ? 15.66786  -8.23585  24.86434  1.000 10.47144  ? 66  MET A N    1 
ATOM   765  C CA   . MET A 1 52  ? 15.70295  -7.15992  23.88637  1.000 10.38497  ? 66  MET A CA   1 
ATOM   766  C C    . MET A 1 52  ? 14.28691  -6.60950  23.79489  1.000 10.53445  ? 66  MET A C    1 
ATOM   767  O O    . MET A 1 52  ? 13.38194  -7.28434  23.29188  1.000 11.39619  ? 66  MET A O    1 
ATOM   768  C CB   . MET A 1 52  ? 16.17501  -7.72637  22.55755  1.000 10.56935  ? 66  MET A CB   1 
ATOM   769  C CG   . MET A 1 52  ? 16.14475  -6.74651  21.39070  1.000 11.29451  ? 66  MET A CG   1 
ATOM   770  S SD   . MET A 1 52  ? 16.94021  -7.35243  19.90891  1.000 11.91970  ? 66  MET A SD   1 
ATOM   771  C CE   . MET A 1 52  ? 15.97441  -8.80429  19.49697  1.000 11.47883  ? 66  MET A CE   1 
ATOM   772  H H    . MET A 1 52  ? 15.63652  -9.02444  24.52267  1.000 12.56063  ? 66  MET A H    1 
ATOM   773  H HA   . MET A 1 52  ? 16.31368  -6.45214  24.14514  1.000 12.45685  ? 66  MET A HA   1 
ATOM   774  H HB2  . MET A 1 52  ? 17.09139  -8.02725  22.66058  1.000 12.67811  ? 66  MET A HB2  1 
ATOM   775  H HB3  . MET A 1 52  ? 15.60440  -8.47495  22.32319  1.000 12.67811  ? 66  MET A HB3  1 
ATOM   776  H HG2  . MET A 1 52  ? 15.21998  -6.55360  21.17049  1.000 13.54830  ? 66  MET A HG2  1 
ATOM   777  H HG3  . MET A 1 52  ? 16.59930  -5.93195  21.65675  0.506 13.54830  ? 66  MET A HG3  1 
ATOM   778  H HE1  . MET A 1 52  ? 16.30120  -9.17453  18.66208  0.954 13.76949  ? 66  MET A HE1  1 
ATOM   779  H HE2  . MET A 1 52  ? 16.06783  -9.45782  20.20765  0.905 13.76949  ? 66  MET A HE2  1 
ATOM   780  H HE3  . MET A 1 52  ? 15.04352  -8.54822  19.40335  1.000 13.76949  ? 66  MET A HE3  1 
ATOM   781  N N    . GLN A 1 53  ? 14.05673  -5.43183  24.36662  1.000 10.84225  ? 67  GLN A N    1 
ATOM   782  C CA   . GLN A 1 53  ? 12.72257  -4.86889  24.50746  1.000 10.77916  ? 67  GLN A CA   1 
ATOM   783  C C    . GLN A 1 53  ? 12.52141  -3.73500  23.52385  1.000 10.66715  ? 67  GLN A C    1 
ATOM   784  O O    . GLN A 1 53  ? 13.32151  -2.78849  23.46810  1.000 11.03680  ? 67  GLN A O    1 
ATOM   785  C CB   . GLN A 1 53  ? 12.47459  -4.35920  25.92364  1.000 11.31402  ? 67  GLN A CB   1 
ATOM   786  C CG   . GLN A 1 53  ? 11.06514  -3.84755  26.10183  1.000 11.91992  ? 67  GLN A CG   1 
ATOM   787  C CD   . GLN A 1 53  ? 10.80299  -3.40925  27.50861  1.000 12.45916  ? 67  GLN A CD   1 
ATOM   788  O OE1  . GLN A 1 53  ? 10.28830  -4.17076  28.31668  1.000 13.98521  ? 67  GLN A OE1  1 
ATOM   789  N NE2  . GLN A 1 53  ? 11.16741  -2.17248  27.81972  1.000 14.30023  ? 67  GLN A NE2  1 
ATOM   790  H H    . GLN A 1 53  ? 14.67554  -4.92874  24.68846  1.000 13.00559  ? 67  GLN A H    1 
ATOM   791  H HA   . GLN A 1 53  ? 12.07879  -5.56672  24.30878  1.000 12.92989  ? 67  GLN A HA   1 
ATOM   792  H HB2  . GLN A 1 53  ? 12.61622  -5.08405  26.55247  1.000 13.57171  ? 67  GLN A HB2  1 
ATOM   793  H HB3  . GLN A 1 53  ? 13.08781  -3.63171  26.11235  1.000 13.57171  ? 67  GLN A HB3  1 
ATOM   794  H HG2  . GLN A 1 53  ? 10.92511  -3.08717  25.51607  1.000 14.29879  ? 67  GLN A HG2  1 
ATOM   795  H HG3  . GLN A 1 53  ? 10.43864  -4.55493  25.88272  1.000 14.29879  ? 67  GLN A HG3  1 
ATOM   796  H HE21 . GLN A 1 53  ? 11.53308  -1.66962  27.22557  1.000 17.15517  ? 67  GLN A HE21 1 
ATOM   797  H HE22 . GLN A 1 53  ? 11.03804  -1.87342  28.61560  0.941 17.15517  ? 67  GLN A HE22 1 
ATOM   798  N N    . PHE A 1 54  ? 11.41350  -3.82251  22.80060  1.000 10.08511  ? 68  PHE A N    1 
ATOM   799  C CA   . PHE A 1 54  ? 10.96984  -2.81382  21.84585  1.000 10.80511  ? 68  PHE A CA   1 
ATOM   800  C C    . PHE A 1 54  ? 9.75036   -2.10259  22.41231  1.000 11.40529  ? 68  PHE A C    1 
ATOM   801  O O    . PHE A 1 54  ? 8.84379   -2.74463  22.93667  1.000 11.68152  ? 68  PHE A O    1 
ATOM   802  C CB   . PHE A 1 54  ? 10.52944  -3.50018  20.55507  1.000 10.90543  ? 68  PHE A CB   1 
ATOM   803  C CG   . PHE A 1 54  ? 11.60881  -4.29488  19.87564  1.000 10.00849  ? 68  PHE A CG   1 
ATOM   804  C CD1  . PHE A 1 54  ? 11.85117  -5.61077  20.22703  1.000 10.23324  ? 68  PHE A CD1  1 
ATOM   805  C CD2  . PHE A 1 54  ? 12.36244  -3.74322  18.86693  1.000 10.78022  ? 68  PHE A CD2  1 
ATOM   806  C CE1  . PHE A 1 54  ? 12.84744  -6.34441  19.58296  1.000 10.47948  ? 68  PHE A CE1  1 
ATOM   807  C CE2  . PHE A 1 54  ? 13.33307  -4.47590  18.21975  1.000 10.89966  ? 68  PHE A CE2  1 
ATOM   808  C CZ   . PHE A 1 54  ? 13.57689  -5.77585  18.58411  1.000 10.60165  ? 68  PHE A CZ   1 
ATOM   809  H H    . PHE A 1 54  ? 10.87403  -4.49065  22.84704  1.000 12.09702  ? 68  PHE A H    1 
ATOM   810  H HA   . PHE A 1 54  ? 11.68100  -2.17689  21.67415  1.000 12.96102  ? 68  PHE A HA   1 
ATOM   811  H HB2  . PHE A 1 54  ? 9.80241   -4.10854  20.76056  1.000 13.08140  ? 68  PHE A HB2  1 
ATOM   812  H HB3  . PHE A 1 54  ? 10.22784  -2.82154  19.93106  1.000 13.08140  ? 68  PHE A HB3  1 
ATOM   813  H HD1  . PHE A 1 54  ? 11.34572  -6.00950  20.89817  1.000 12.27478  ? 68  PHE A HD1  1 
ATOM   814  H HD2  . PHE A 1 54  ? 12.21440  -2.85975  18.61701  1.000 12.93115  ? 68  PHE A HD2  1 
ATOM   815  H HE1  . PHE A 1 54  ? 13.01365  -7.22363  19.83641  1.000 12.57027  ? 68  PHE A HE1  1 
ATOM   816  H HE2  . PHE A 1 54  ? 13.82521  -4.08758  17.53280  0.832 13.07448  ? 68  PHE A HE2  1 
ATOM   817  H HZ   . PHE A 1 54  ? 14.23751  -6.26640  18.15071  1.000 12.71687  ? 68  PHE A HZ   1 
ATOM   818  N N    . GLN A 1 55  ? 9.70656   -0.78082  22.26281  1.000 11.39119  ? 69  GLN A N    1 
ATOM   819  C CA   . GLN A 1 55  ? 8.55352   0.02297   22.67431  1.000 11.99626  ? 69  GLN A CA   1 
ATOM   820  C C    . GLN A 1 55  ? 8.21641   1.03013   21.59285  1.000 12.02845  ? 69  GLN A C    1 
ATOM   821  O O    . GLN A 1 55  ? 9.11719   1.66956   21.04643  1.000 13.09165  ? 69  GLN A O    1 
ATOM   822  C CB   . GLN A 1 55  ? 8.84944   0.83046   23.95991  1.000 14.82746  ? 69  GLN A CB   1 
ATOM   823  C CG   . GLN A 1 55  ? 8.89538   -0.01166  25.20188  1.000 15.96607  ? 69  GLN A CG   1 
ATOM   824  C CD   . GLN A 1 55  ? 8.93921   0.82072   26.45502  1.000 16.54370  ? 69  GLN A CD   1 
ATOM   825  O OE1  . GLN A 1 55  ? 7.99548   0.81274   27.23707  1.000 18.28926  ? 69  GLN A OE1  1 
ATOM   826  N NE2  . GLN A 1 55  ? 10.03426  1.54748   26.66452  1.000 16.95672  ? 69  GLN A NE2  1 
ATOM   827  H H    . GLN A 1 55  ? 10.34347  -0.31612  21.91929  1.000 13.66433  ? 69  GLN A H    1 
ATOM   828  H HA   . GLN A 1 55  ? 7.80526   -0.57740  22.81768  1.000 14.39041  ? 69  GLN A HA   1 
ATOM   829  H HB2  . GLN A 1 55  ? 9.71121   1.26530   23.86420  0.729 17.78785  ? 69  GLN A HB2  1 
ATOM   830  H HB3  . GLN A 1 55  ? 8.15346   1.49571   24.07805  1.000 17.78785  ? 69  GLN A HB3  1 
ATOM   831  H HG2  . GLN A 1 55  ? 8.10240   -0.56918  25.23739  1.000 19.15417  ? 69  GLN A HG2  1 
ATOM   832  H HG3  . GLN A 1 55  ? 9.69053   -0.56679  25.18026  1.000 19.15417  ? 69  GLN A HG3  1 
ATOM   833  H HE21 . GLN A 1 55  ? 10.67858  1.52818   26.09525  0.157 20.34296  ? 69  GLN A HE21 1 
ATOM   834  H HE22 . GLN A 1 55  ? 10.09755  2.03642   27.36918  1.000 20.34296  ? 69  GLN A HE22 1 
ATOM   835  N N    . ILE A 1 56  ? 6.92217   1.20102   21.32028  1.000 12.24352  ? 70  ILE A N    1 
ATOM   836  C CA   . ILE A 1 56  ? 6.48723   2.18184   20.32840  1.000 12.63843  ? 70  ILE A CA   1 
ATOM   837  C C    . ILE A 1 56  ? 5.03141   2.54100   20.56477  1.000 13.07540  ? 70  ILE A C    1 
ATOM   838  O O    . ILE A 1 56  ? 4.19739   1.67499   20.82665  1.000 13.73449  ? 70  ILE A O    1 
ATOM   839  C CB   . ILE A 1 56  ? 6.70654   1.63321   18.90227  1.000 12.83969  ? 70  ILE A CB   1 
ATOM   840  C CG1  . ILE A 1 56  ? 6.40479   2.70456   17.85492  1.000 13.79778  ? 70  ILE A CG1  1 
ATOM   841  C CG2  . ILE A 1 56  ? 5.84260   0.40622   18.63871  1.000 13.50966  ? 70  ILE A CG2  1 
ATOM   842  C CD1  . ILE A 1 56  ? 7.34921   3.88150   17.88951  1.000 14.89328  ? 70  ILE A CD1  1 
ATOM   843  H H    . ILE A 1 56  ? 6.28270   0.76399   21.69401  0.636 14.68711  ? 70  ILE A H    1 
ATOM   844  H HA   . ILE A 1 56  ? 7.00375   2.99371   20.45077  1.000 15.16101  ? 70  ILE A HA   1 
ATOM   845  H HB   . ILE A 1 56  ? 7.63976   1.37674   18.83731  1.000 15.40252  ? 70  ILE A HB   1 
ATOM   846  H HG12 . ILE A 1 56  ? 6.46551   2.30359   16.97376  1.000 16.55222  ? 70  ILE A HG12 1 
ATOM   847  H HG13 . ILE A 1 56  ? 5.50775   3.04182   18.00484  1.000 16.55222  ? 70  ILE A HG13 1 
ATOM   848  H HG21 . ILE A 1 56  ? 4.96091   0.69556   18.35621  1.000 16.20648  ? 70  ILE A HG21 1 
ATOM   849  H HG22 . ILE A 1 56  ? 6.25521   -0.12658  17.94101  0.866 16.20648  ? 70  ILE A HG22 1 
ATOM   850  H HG23 . ILE A 1 56  ? 5.77447   -0.11330  19.45502  0.790 16.20648  ? 70  ILE A HG23 1 
ATOM   851  H HD11 . ILE A 1 56  ? 7.61804   4.09743   16.98287  0.714 17.86683  ? 70  ILE A HD11 1 
ATOM   852  H HD12 . ILE A 1 56  ? 6.89466   4.63951   18.28916  0.928 17.86683  ? 70  ILE A HD12 1 
ATOM   853  H HD13 . ILE A 1 56  ? 8.12769   3.64629   18.41822  1.000 17.86683  ? 70  ILE A HD13 1 
ATOM   854  N N    . ALA A 1 57  ? 4.72784   3.83432   20.41845  1.000 13.35266  ? 71  ALA A N    1 
ATOM   855  C CA   . ALA A 1 57  ? 3.36550   4.35216   20.41122  1.000 14.63969  ? 71  ALA A CA   1 
ATOM   856  C C    . ALA A 1 57  ? 3.03660   4.95471   19.05179  1.000 15.02622  ? 71  ALA A C    1 
ATOM   857  O O    . ALA A 1 57  ? 3.92953   5.38166   18.31393  1.000 15.56677  ? 71  ALA A O    1 
ATOM   858  C CB   . ALA A 1 57  ? 3.18155   5.43784   21.48062  1.000 15.33805  ? 71  ALA A CB   1 
ATOM   859  H H    . ALA A 1 57  ? 5.31947   4.45038   20.31829  1.000 16.01808  ? 71  ALA A H    1 
ATOM   860  H HA   . ALA A 1 57  ? 2.75174   3.62162   20.58585  1.000 17.56252  ? 71  ALA A HA   1 
ATOM   861  H HB1  . ALA A 1 57  ? 3.87715   6.10568   21.37556  1.000 18.40055  ? 71  ALA A HB1  1 
ATOM   862  H HB2  . ALA A 1 57  ? 2.30969   5.84776   21.36778  0.325 18.40055  ? 71  ALA A HB2  1 
ATOM   863  H HB3  . ALA A 1 57  ? 3.24427   5.03018   22.35856  1.000 18.40055  ? 71  ALA A HB3  1 
ATOM   864  N N    . GLY A 1 58  ? 1.75371   4.98196   18.72834  1.000 15.69632  ? 72  GLY A N    1 
ATOM   865  C CA   . GLY A 1 58  ? 1.25498   5.69241   17.56502  1.000 16.25320  ? 72  GLY A CA   1 
ATOM   866  C C    . GLY A 1 58  ? 0.84582   4.73954   16.45434  1.000 15.92117  ? 72  GLY A C    1 
ATOM   867  O O    . GLY A 1 58  ? 1.42309   3.65752   16.27548  1.000 15.94542  ? 72  GLY A O    1 
ATOM   868  H H    . GLY A 1 58  ? 1.13662   4.58660   19.17832  0.525 18.83047  ? 72  GLY A H    1 
ATOM   869  H HA2  . GLY A 1 58  ? 0.48239   6.22241   17.81623  1.000 19.49874  ? 72  GLY A HA2  1 
ATOM   870  H HA3  . GLY A 1 58  ? 1.94591   6.28254   17.22551  1.000 19.49874  ? 72  GLY A HA3  1 
ATOM   871  N N    . SER A 1 59  ? -0.16195  5.15255   15.68944  1.000 16.23377  ? 73  SER A N    1 
ATOM   872  C CA   . SER A 1 59  ? -0.73147  4.30273   14.64911  1.000 17.11554  ? 73  SER A CA   1 
ATOM   873  C C    . SER A 1 59  ? 0.28100   4.01419   13.55733  1.000 16.56682  ? 73  SER A C    1 
ATOM   874  O O    . SER A 1 59  ? 0.79671   4.93396   12.91296  1.000 17.20103  ? 73  SER A O    1 
ATOM   875  C CB   . SER A 1 59  ? -1.94391  4.98778   14.03079  1.000 18.90332  ? 73  SER A CB   1 
ATOM   876  O OG   . SER A 1 59  ? -3.03220  5.02163   14.92657  1.000 20.60821  ? 73  SER A OG   1 
ATOM   877  H H    . SER A 1 59  ? -0.53557  5.92452   15.75325  1.000 19.47542  ? 73  SER A H    1 
ATOM   878  H HA   . SER A 1 59  ? -0.99879  3.46353   15.05553  1.000 20.53354  ? 73  SER A HA   1 
ATOM   879  H HB2  . SER A 1 59  ? -1.70338  5.89769   13.79603  1.000 22.67888  ? 73  SER A HB2  1 
ATOM   880  H HB3  . SER A 1 59  ? -2.20805  4.49882   13.23577  1.000 22.67888  ? 73  SER A HB3  1 
ATOM   881  H HG   . SER A 1 59  ? -2.76885  5.25278   15.68999  1.000 24.72474  ? 73  SER A HG   1 
ATOM   882  N N    . SER A 1 60  ? 0.54064   2.72685   13.33138  1.000 15.73122  ? 74  SER A N    1 
ATOM   883  C CA   . SER A 1 60  ? 1.43113   2.23393   12.29061  1.000 15.93159  ? 74  SER A CA   1 
ATOM   884  C C    . SER A 1 60  ? 2.88075   2.63585   12.50607  1.000 15.29786  ? 74  SER A C    1 
ATOM   885  O O    . SER A 1 60  ? 3.69973   2.47887   11.59846  1.000 16.34915  ? 74  SER A O    1 
ATOM   886  C CB   . SER A 1 60  ? 0.95260   2.61208   10.88858  1.000 17.70156  ? 74  SER A CB   1 
ATOM   887  O OG   . SER A 1 60  ? -0.29225  1.99559   10.65102  1.000 20.37098  ? 74  SER A OG   1 
ATOM   888  H H    . SER A 1 60  ? 0.19209   2.09180   13.79487  1.000 18.87236  ? 74  SER A H    1 
ATOM   889  H HA   . SER A 1 60  ? 1.41872   1.26470   12.32733  0.651 19.11280  ? 74  SER A HA   1 
ATOM   890  H HB2  . SER A 1 60  ? 0.85349   3.57518   10.82912  1.000 21.23677  ? 74  SER A HB2  1 
ATOM   891  H HB3  . SER A 1 60  ? 1.59702   2.30375   10.23242  1.000 21.23677  ? 74  SER A HB3  1 
ATOM   892  H HG   . SER A 1 60  ? -0.51762  2.10296   9.84897   1.000 24.44007  ? 74  SER A HG   1 
ATOM   893  N N    . ASN A 1 61  ? 3.22292   3.15593   13.67813  1.000 13.78314  ? 75  ASN A N    1 
ATOM   894  C CA   A ASN A 1 61  ? 4.61939   3.33499   14.02518  0.000 13.23761  ? 75  ASN A CA   1 
ATOM   895  C CA   B ASN A 1 61  ? 4.61838   3.33296   14.02364  1.000 13.38252  ? 75  ASN A CA   1 
ATOM   896  C C    . ASN A 1 61  ? 5.22696   1.99083   14.40784  1.000 12.67723  ? 75  ASN A C    1 
ATOM   897  O O    . ASN A 1 61  ? 4.52424   1.01853   14.69508  1.000 12.94701  ? 75  ASN A O    1 
ATOM   898  C CB   A ASN A 1 61  ? 4.76598   4.31861   15.18616  0.000 13.32890  ? 75  ASN A CB   1 
ATOM   899  C CB   B ASN A 1 61  ? 4.75678   4.31573   15.17453  1.000 14.90996  ? 75  ASN A CB   1 
ATOM   900  C CG   A ASN A 1 61  ? 4.52964   5.75612   14.76645  0.000 13.39990  ? 75  ASN A CG   1 
ATOM   901  C CG   B ASN A 1 61  ? 4.47814   5.72431   14.75882  1.000 17.39635  ? 75  ASN A CG   1 
ATOM   902  O OD1  A ASN A 1 61  ? 4.77995   6.12980   13.62068  0.000 13.42071  ? 75  ASN A OD1  1 
ATOM   903  O OD1  B ASN A 1 61  ? 4.65460   6.09643   13.59690  1.000 19.61900  ? 75  ASN A OD1  1 
ATOM   904  N ND2  A ASN A 1 61  ? 4.04865   6.57233   15.69644  0.000 13.42071  ? 75  ASN A ND2  1 
ATOM   905  N ND2  B ASN A 1 61  ? 4.05768   6.53257   15.70902  1.000 20.85262  ? 75  ASN A ND2  1 
ATOM   906  H H    . ASN A 1 61  ? 2.66832   3.41127   14.28379  1.000 16.53466  ? 75  ASN A H    1 
ATOM   907  H HA   . ASN A 1 61  ? 5.10280   3.69717   13.26621  1.000 16.05391  ? 75  ASN A HA   1 
ATOM   908  H HB2  A ASN A 1 61  ? 4.11860   4.09595   15.87335  0.000 15.98957  ? 75  ASN A HB2  1 
ATOM   909  H HB2  B ASN A 1 61  ? 4.12695   4.07747   15.87271  1.000 17.88685  ? 75  ASN A HB2  1 
ATOM   910  H HB3  A ASN A 1 61  ? 5.66521   4.25409   15.54409  0.000 15.98957  ? 75  ASN A HB3  1 
ATOM   911  H HB3  B ASN A 1 61  ? 5.66314   4.27664   15.51789  1.000 17.88685  ? 75  ASN A HB3  1 
ATOM   912  H HD21 A ASN A 1 61  ? 3.89746   7.39764   15.50773  0.000 16.09974  ? 75  ASN A HD21 1 
ATOM   913  H HD21 B ASN A 1 61  ? 3.88166   7.35459   15.52763  1.000 25.01804  ? 75  ASN A HD21 1 
ATOM   914  H HD22 A ASN A 1 61  ? 3.88826   6.27577   16.48759  0.000 16.09974  ? 75  ASN A HD22 1 
ATOM   915  H HD22 B ASN A 1 61  ? 3.95903   6.23858   16.51117  1.000 25.01804  ? 75  ASN A HD22 1 
ATOM   916  N N    . ARG A 1 62  ? 6.55412   1.94691   14.41291  1.000 11.68616  ? 76  ARG A N    1 
ATOM   917  C CA   . ARG A 1 62  ? 7.24145   0.70117   14.69926  1.000 11.39343  ? 76  ARG A CA   1 
ATOM   918  C C    . ARG A 1 62  ? 8.56826   0.96140   15.38394  1.000 11.19989  ? 76  ARG A C    1 
ATOM   919  O O    . ARG A 1 62  ? 9.15428   2.04414   15.28660  1.000 11.98642  ? 76  ARG A O    1 
ATOM   920  C CB   . ARG A 1 62  ? 7.51802   -0.08218  13.41679  1.000 12.01541  ? 76  ARG A CB   1 
ATOM   921  C CG   . ARG A 1 62  ? 8.50536   0.60799   12.48891  1.000 12.66543  ? 76  ARG A CG   1 
ATOM   922  C CD   . ARG A 1 62  ? 8.53777   -0.02427  11.11039  1.000 14.00193  ? 76  ARG A CD   1 
ATOM   923  N NE   . ARG A 1 62  ? 7.36531   0.34420   10.32260  1.000 14.12521  ? 76  ARG A NE   1 
ATOM   924  C CZ   . ARG A 1 62  ? 6.61108   -0.48947  9.61694   1.000 14.68916  ? 76  ARG A CZ   1 
ATOM   925  N NH1  . ARG A 1 62  ? 6.77514   -1.79643  9.67403   1.000 14.97562  ? 76  ARG A NH1  1 
ATOM   926  N NH2  . ARG A 1 62  ? 5.67418   0.00620   8.81538   1.000 15.21207  ? 76  ARG A NH2  1 
ATOM   927  H H    . ARG A 1 62  ? 7.06929   2.61727   14.25539  1.000 14.01828  ? 76  ARG A H    1 
ATOM   928  H HA   . ARG A 1 62  ? 6.67917   0.18964   15.30181  1.000 13.66701  ? 76  ARG A HA   1 
ATOM   929  H HB2  . ARG A 1 62  ? 7.88601   -0.94829  13.65200  1.000 14.41339  ? 76  ARG A HB2  1 
ATOM   930  H HB3  . ARG A 1 62  ? 6.68477   -0.19592  12.93340  1.000 14.41339  ? 76  ARG A HB3  1 
ATOM   931  H HG2  . ARG A 1 62  ? 8.25035   1.53841   12.38799  1.000 15.19341  ? 76  ARG A HG2  1 
ATOM   932  H HG3  . ARG A 1 62  ? 9.39554   0.54738   12.86944  1.000 15.19341  ? 76  ARG A HG3  1 
ATOM   933  H HD2  . ARG A 1 62  ? 9.32939   0.27721   10.63780  1.000 16.79721  ? 76  ARG A HD2  1 
ATOM   934  H HD3  . ARG A 1 62  ? 8.55293   -0.98993  11.20071  1.000 16.79721  ? 76  ARG A HD3  1 
ATOM   935  H HE   . ARG A 1 62  ? 7.14360   1.17510   10.31503  1.000 16.94515  ? 76  ARG A HE   1 
ATOM   936  H HH11 . ARG A 1 62  ? 7.38505   -2.13158  10.17928  1.000 17.96564  ? 76  ARG A HH11 1 
ATOM   937  H HH12 . ARG A 1 62  ? 6.27224   -2.31378  9.20601   1.000 17.96564  ? 76  ARG A HH12 1 
ATOM   938  H HH21 . ARG A 1 62  ? 5.56279   0.85708   8.75886   1.000 18.24938  ? 76  ARG A HH21 1 
ATOM   939  H HH22 . ARG A 1 62  ? 5.17926   -0.52390  8.35316   0.416 18.24938  ? 76  ARG A HH22 1 
ATOM   940  N N    . CYS A 1 63  ? 9.03824   -0.08128  16.06112  1.000 11.18012  ? 77  CYS A N    1 
ATOM   941  C CA   . CYS A 1 63  ? 10.43045  -0.20829  16.46329  1.000 10.83934  ? 77  CYS A CA   1 
ATOM   942  C C    . CYS A 1 63  ? 10.73836  -1.65456  16.10804  1.000 10.50859  ? 77  CYS A C    1 
ATOM   943  O O    . CYS A 1 63  ? 10.28635  -2.57377  16.79696  1.000 10.86635  ? 77  CYS A O    1 
ATOM   944  C CB   . CYS A 1 63  ? 10.64276  0.05053   17.94820  1.000 12.36145  ? 77  CYS A CB   1 
ATOM   945  S SG   . CYS A 1 63  ? 12.37232  0.12040   18.29716  1.000 12.52599  ? 77  CYS A SG   1 
ATOM   946  H H    . CYS A 1 63  ? 8.55322   -0.74792  16.30597  1.000 13.41103  ? 77  CYS A H    1 
ATOM   947  H HA   . CYS A 1 63  ? 10.99996  0.42401   15.99773  1.000 13.00210  ? 77  CYS A HA   1 
ATOM   948  H HB2  . CYS A 1 63  ? 10.23886  0.89748   18.19404  1.000 14.82863  ? 77  CYS A HB2  1 
ATOM   949  H HB3  . CYS A 1 63  ? 10.24729  -0.66825  18.46575  1.000 14.82863  ? 77  CYS A HB3  1 
ATOM   950  H HG   . CYS A 1 63  ? 12.52642  0.38963   19.45637  1.000 15.02608  ? 77  CYS A HG   1 
ATOM   951  N N    . GLU A 1 64  ? 11.42923  -1.85894  14.98808  1.000 11.39940  ? 78  GLU A N    1 
ATOM   952  C CA   A GLU A 1 64  ? 11.52234  -3.18181  14.40337  0.431 11.59540  ? 78  GLU A CA   1 
ATOM   953  C CA   B GLU A 1 64  ? 11.52850  -3.18469  14.39650  0.569 11.79531  ? 78  GLU A CA   1 
ATOM   954  C C    . GLU A 1 64  ? 12.89554  -3.40094  13.79019  1.000 11.19925  ? 78  GLU A C    1 
ATOM   955  O O    . GLU A 1 64  ? 13.44636  -2.50110  13.15198  1.000 12.66170  ? 78  GLU A O    1 
ATOM   956  C CB   A GLU A 1 64  ? 10.42527  -3.29304  13.34438  0.431 13.17429  ? 78  GLU A CB   1 
ATOM   957  C CB   B GLU A 1 64  ? 10.56220  -3.35238  13.22090  0.569 14.12979  ? 78  GLU A CB   1 
ATOM   958  C CG   A GLU A 1 64  ? 10.07129  -4.68043  12.90537  0.431 13.19879  ? 78  GLU A CG   1 
ATOM   959  C CG   B GLU A 1 64  ? 9.17563   -3.85006  13.51303  0.569 13.88901  ? 78  GLU A CG   1 
ATOM   960  C CD   A GLU A 1 64  ? 8.85746   -4.69451  11.98056  0.431 14.22625  ? 78  GLU A CD   1 
ATOM   961  C CD   B GLU A 1 64  ? 8.43329   -4.20076  12.22862  0.569 12.84249  ? 78  GLU A CD   1 
ATOM   962  O OE1  A GLU A 1 64  ? 8.60690   -3.67546  11.29475  0.431 15.08412  ? 78  GLU A OE1  1 
ATOM   963  O OE1  B GLU A 1 64  ? 8.33186   -3.32482  11.33283  0.569 13.15571  ? 78  GLU A OE1  1 
ATOM   964  O OE2  A GLU A 1 64  ? 8.15404   -5.72730  11.94434  0.431 14.54104  ? 78  GLU A OE2  1 
ATOM   965  O OE2  B GLU A 1 64  ? 7.97115   -5.35381  12.10183  0.569 13.23216  ? 78  GLU A OE2  1 
ATOM   966  H H    . GLU A 1 64  ? 11.84692  -1.24339  14.55652  1.000 13.67418  ? 78  GLU A H    1 
ATOM   967  H HA   . GLU A 1 64  ? 11.42580  -3.87771  15.07217  1.000 14.14927  ? 78  GLU A HA   1 
ATOM   968  H HB2  A GLU A 1 64  ? 9.61789   -2.89133  13.70169  0.431 15.80404  ? 78  GLU A HB2  1 
ATOM   969  H HB2  B GLU A 1 64  ? 10.46257  -2.48664  12.79492  0.569 16.95063  ? 78  GLU A HB2  1 
ATOM   970  H HB3  A GLU A 1 64  ? 10.71574  -2.80881  12.55568  0.431 15.80404  ? 78  GLU A HB3  1 
ATOM   971  H HB3  B GLU A 1 64  ? 10.95894  -3.98371  12.60047  0.569 16.95063  ? 78  GLU A HB3  1 
ATOM   972  H HG2  A GLU A 1 64  ? 10.82202  -5.06483  12.42626  0.431 15.83344  ? 78  GLU A HG2  1 
ATOM   973  H HG2  B GLU A 1 64  ? 9.22887   -4.64695  14.06352  0.569 16.66170  ? 78  GLU A HG2  1 
ATOM   974  H HG3  A GLU A 1 64  ? 9.86461   -5.21893  13.68524  0.431 15.83344  ? 78  GLU A HG3  1 
ATOM   975  H HG3  B GLU A 1 64  ? 8.67661   -3.15938  13.97654  0.569 16.66170  ? 78  GLU A HG3  1 
ATOM   976  N N    . LEU A 1 65  ? 13.41098  -4.61350  13.96631  1.000 10.76641  ? 79  LEU A N    1 
ATOM   977  C CA   . LEU A 1 65  ? 14.57685  -5.05344  13.22744  1.000 11.19833  ? 79  LEU A CA   1 
ATOM   978  C C    . LEU A 1 65  ? 14.15470  -5.55633  11.85394  1.000 10.42680  ? 79  LEU A C    1 
ATOM   979  O O    . LEU A 1 65  ? 13.11244  -6.19574  11.70184  1.000 12.03178  ? 79  LEU A O    1 
ATOM   980  C CB   . LEU A 1 65  ? 15.29747  -6.17137  13.97115  1.000 11.73639  ? 79  LEU A CB   1 
ATOM   981  C CG   . LEU A 1 65  ? 15.90073  -5.77977  15.31919  1.000 11.98919  ? 79  LEU A CG   1 
ATOM   982  C CD1  . LEU A 1 65  ? 16.39224  -7.01982  16.06257  1.000 12.47315  ? 79  LEU A CD1  1 
ATOM   983  C CD2  . LEU A 1 65  ? 17.01361  -4.76114  15.17463  1.000 12.37018  ? 79  LEU A CD2  1 
ATOM   984  H H    . LEU A 1 65  ? 13.09865  -5.20010  14.51215  1.000 12.91458  ? 79  LEU A H    1 
ATOM   985  H HA   . LEU A 1 65  ? 15.19251  -4.31095  13.12463  0.810 13.43289  ? 79  LEU A HA   1 
ATOM   986  H HB2  . LEU A 1 65  ? 14.66319  -6.88684  14.13451  1.000 14.07856  ? 79  LEU A HB2  1 
ATOM   987  H HB3  . LEU A 1 65  ? 16.02214  -6.49178  13.41161  1.000 14.07856  ? 79  LEU A HB3  1 
ATOM   988  H HG   . LEU A 1 65  ? 15.20547  -5.35789  15.84790  1.000 14.38192  ? 79  LEU A HG   1 
ATOM   989  H HD11 . LEU A 1 65  ? 16.77929  -6.74769  16.90934  1.000 14.96268  ? 79  LEU A HD11 1 
ATOM   990  H HD12 . LEU A 1 65  ? 15.64096  -7.61343  16.21783  0.299 14.96268  ? 79  LEU A HD12 1 
ATOM   991  H HD13 . LEU A 1 65  ? 17.06142  -7.46770  15.52172  1.000 14.96268  ? 79  LEU A HD13 1 
ATOM   992  H HD21 . LEU A 1 65  ? 16.65877  -3.96365  14.75155  1.000 14.83911  ? 79  LEU A HD21 1 
ATOM   993  H HD22 . LEU A 1 65  ? 17.35848  -4.54316  16.05466  1.000 14.83911  ? 79  LEU A HD22 1 
ATOM   994  H HD23 . LEU A 1 65  ? 17.71924  -5.13986  14.62732  1.000 14.83911  ? 79  LEU A HD23 1 
ATOM   995  N N    . ARG A 1 66  ? 14.97239  -5.24718  10.85626  1.000 10.87125  ? 80  ARG A N    1 
ATOM   996  C CA   . ARG A 1 66  ? 14.73050  -5.57065  9.46036   1.000 11.34512  ? 80  ARG A CA   1 
ATOM   997  C C    . ARG A 1 66  ? 15.95988  -6.31731  8.96005   1.000 11.66063  ? 80  ARG A C    1 
ATOM   998  O O    . ARG A 1 66  ? 17.08069  -5.82429  9.09323   1.000 11.83529  ? 80  ARG A O    1 
ATOM   999  C CB   . ARG A 1 66  ? 14.51740  -4.26417  8.68487   1.000 11.99708  ? 80  ARG A CB   1 
ATOM   1000 C CG   . ARG A 1 66  ? 14.01400  -4.37058  7.24550   1.000 12.17285  ? 80  ARG A CG   1 
ATOM   1001 C CD   . ARG A 1 66  ? 15.03533  -4.88258  6.26082   1.000 12.87331  ? 80  ARG A CD   1 
ATOM   1002 N NE   . ARG A 1 66  ? 14.64123  -4.49801  4.91237   1.000 12.87184  ? 80  ARG A NE   1 
ATOM   1003 C CZ   . ARG A 1 66  ? 14.85962  -5.21332  3.82290   1.000 12.99269  ? 80  ARG A CZ   1 
ATOM   1004 N NH1  . ARG A 1 66  ? 15.52103  -6.35290  3.86311   1.000 13.07423  ? 80  ARG A NH1  1 
ATOM   1005 N NH2  . ARG A 1 66  ? 14.39037  -4.77153  2.66311   1.000 14.05374  ? 80  ARG A NH2  1 
ATOM   1006 H H    . ARG A 1 66  ? 15.71396  -4.82696  10.97067  0.586 13.04039  ? 80  ARG A H    1 
ATOM   1007 H HA   . ARG A 1 66  ? 13.95472  -6.13849  9.33140   1.000 13.60904  ? 80  ARG A HA   1 
ATOM   1008 H HB2  . ARG A 1 66  ? 13.86666  -3.73339  9.17036   0.659 14.39139  ? 80  ARG A HB2  1 
ATOM   1009 H HB3  . ARG A 1 66  ? 15.36697  -3.79733  8.65037   1.000 14.39139  ? 80  ARG A HB3  1 
ATOM   1010 H HG2  . ARG A 1 66  ? 13.25888  -4.97910  7.22577   0.310 14.60231  ? 80  ARG A HG2  1 
ATOM   1011 H HG3  . ARG A 1 66  ? 13.73793  -3.48953  6.94811   0.681 14.60231  ? 80  ARG A HG3  1 
ATOM   1012 H HD2  . ARG A 1 66  ? 15.90349  -4.49659  6.45634   1.000 15.44286  ? 80  ARG A HD2  1 
ATOM   1013 H HD3  . ARG A 1 66  ? 15.08377  -5.85012  6.30990   0.735 15.44286  ? 80  ARG A HD3  1 
ATOM   1014 H HE   . ARG A 1 66  ? 14.23438  -3.74626  4.81776   1.000 15.44110  ? 80  ARG A HE   1 
ATOM   1015 H HH11 . ARG A 1 66  ? 15.82303  -6.64860  4.61208   1.000 15.68396  ? 80  ARG A HH11 1 
ATOM   1016 H HH12 . ARG A 1 66  ? 15.65053  -6.80065  3.14037   0.551 15.68396  ? 80  ARG A HH12 1 
ATOM   1017 H HH21 . ARG A 1 66  ? 13.95294  -4.03183  2.62993   1.000 16.85938  ? 80  ARG A HH21 1 
ATOM   1018 H HH22 . ARG A 1 66  ? 14.52366  -5.22487  1.94456   0.621 16.85938  ? 80  ARG A HH22 1 
ATOM   1019 N N    . GLN A 1 67  ? 15.74938  -7.49586  8.38373   1.000 11.22168  ? 81  GLN A N    1 
ATOM   1020 C CA   . GLN A 1 67  ? 16.85593  -8.36781  7.99566   1.000 11.59736  ? 81  GLN A CA   1 
ATOM   1021 C C    . GLN A 1 67  ? 17.76127  -7.72689  6.94674   1.000 11.93888  ? 81  GLN A C    1 
ATOM   1022 O O    . GLN A 1 67  ? 17.29809  -7.21983  5.92116   1.000 13.00672  ? 81  GLN A O    1 
ATOM   1023 C CB   . GLN A 1 67  ? 16.29053  -9.67711  7.45210   1.000 11.99104  ? 81  GLN A CB   1 
ATOM   1024 C CG   . GLN A 1 67  ? 17.33840  -10.74038 7.18197   1.000 12.19101  ? 81  GLN A CG   1 
ATOM   1025 C CD   . GLN A 1 67  ? 16.76112  -11.98670 6.53190   1.000 12.68012  ? 81  GLN A CD   1 
ATOM   1026 O OE1  . GLN A 1 67  ? 15.58820  -12.02663 6.14874   1.000 12.64199  ? 81  GLN A OE1  1 
ATOM   1027 N NE2  . GLN A 1 67  ? 17.59453  -13.00935 6.39669   1.000 15.46667  ? 81  GLN A NE2  1 
ATOM   1028 H H    . GLN A 1 67  ? 14.97216  -7.81748  8.20459   0.527 13.46090  ? 81  GLN A H    1 
ATOM   1029 H HA   . GLN A 1 67  ? 17.40247  -8.53845  8.77865   1.000 13.91172  ? 81  GLN A HA   1 
ATOM   1030 H HB2  . GLN A 1 67  ? 15.66512  -10.03776 8.09994   1.000 14.38414  ? 81  GLN A HB2  1 
ATOM   1031 H HB3  . GLN A 1 67  ? 15.83378  -9.49456  6.61606   1.000 14.38414  ? 81  GLN A HB3  1 
ATOM   1032 H HG2  . GLN A 1 67  ? 18.01142  -10.37610 6.58594   1.000 14.62410  ? 81  GLN A HG2  1 
ATOM   1033 H HG3  . GLN A 1 67  ? 17.74618  -11.00239 8.02220   1.000 14.62410  ? 81  GLN A HG3  1 
ATOM   1034 H HE21 . GLN A 1 67  ? 18.40701  -12.94099 6.67021   0.725 18.55489  ? 81  GLN A HE21 1 
ATOM   1035 H HE22 . GLN A 1 67  ? 17.32252  -13.74088 6.03548   0.391 18.55489  ? 81  GLN A HE22 1 
ATOM   1036 N N    . MET A 1 68  ? 19.06026  -7.78648  7.19843   1.000 12.71710  ? 82  MET A N    1 
ATOM   1037 C CA   . MET A 1 68  ? 20.08036  -7.25740  6.31480   1.000 13.43013  ? 82  MET A CA   1 
ATOM   1038 C C    . MET A 1 68  ? 21.05311  -8.36656  5.94665   1.000 14.16158  ? 82  MET A C    1 
ATOM   1039 O O    . MET A 1 68  ? 21.16513  -9.38202  6.63726   1.000 15.05628  ? 82  MET A O    1 
ATOM   1040 C CB   . MET A 1 68  ? 20.87880  -6.14413  7.00355   1.000 13.68997  ? 82  MET A CB   1 
ATOM   1041 C CG   . MET A 1 68  ? 20.04247  -5.00797  7.50917   1.000 14.27884  ? 82  MET A CG   1 
ATOM   1042 S SD   . MET A 1 68  ? 19.27370  -4.02563  6.20902   1.000 14.75882  ? 82  MET A SD   1 
ATOM   1043 C CE   . MET A 1 68  ? 20.66475  -2.98831  5.76052   1.000 15.96431  ? 82  MET A CE   1 
ATOM   1044 H H    . MET A 1 68  ? 19.38793  -8.14554  7.90787   1.000 15.25541  ? 82  MET A H    1 
ATOM   1045 H HA   . MET A 1 68  ? 19.65319  -6.90194  5.51976   1.000 16.11105  ? 82  MET A HA   1 
ATOM   1046 H HB2  . MET A 1 68  ? 21.34835  -6.52391  7.76262   1.000 16.42285  ? 82  MET A HB2  1 
ATOM   1047 H HB3  . MET A 1 68  ? 21.51499  -5.78058  6.36795   1.000 16.42285  ? 82  MET A HB3  1 
ATOM   1048 H HG2  . MET A 1 68  ? 19.33329  -5.36717  8.06499   0.561 17.12950  ? 82  MET A HG2  1 
ATOM   1049 H HG3  . MET A 1 68  ? 20.60567  -4.41568  8.03156   0.852 17.12950  ? 82  MET A HG3  1 
ATOM   1050 H HE1  . MET A 1 68  ? 20.40235  -2.40666  5.02996   1.000 19.15206  ? 82  MET A HE1  1 
ATOM   1051 H HE2  . MET A 1 68  ? 20.92347  -2.45704  6.52976   1.000 19.15206  ? 82  MET A HE2  1 
ATOM   1052 H HE3  . MET A 1 68  ? 21.40375  -3.55289  5.48478   1.000 19.15206  ? 82  MET A HE3  1 
ATOM   1053 N N    . ILE A 1 69  ? 21.76222  -8.14802  4.84795   1.000 15.43255  ? 83  ILE A N    1 
ATOM   1054 C CA   . ILE A 1 69  ? 22.90506  -9.00364  4.52525   1.000 17.06373  ? 83  ILE A CA   1 
ATOM   1055 C C    . ILE A 1 69  ? 23.91050  -8.91531  5.66613   1.000 16.82241  ? 83  ILE A C    1 
ATOM   1056 O O    . ILE A 1 69  ? 24.17934  -7.80559  6.16304   1.000 16.75031  ? 83  ILE A O    1 
ATOM   1057 C CB   . ILE A 1 69  ? 23.52254  -8.54426  3.19995   1.000 18.51242  ? 83  ILE A CB   1 
ATOM   1058 C CG1  . ILE A 1 69  ? 22.51337  -8.78396  2.07142   1.000 20.18672  ? 83  ILE A CG1  1 
ATOM   1059 C CG2  . ILE A 1 69  ? 24.85914  -9.24846  2.94163   1.000 19.93402  ? 83  ILE A CG2  1 
ATOM   1060 C CD1  . ILE A 1 69  ? 22.84447  -8.08129  0.77622   1.000 21.96482  ? 83  ILE A CD1  1 
ATOM   1061 H H    . ILE A 1 69  ? 21.60947  -7.52232  4.27807   1.000 18.51395  ? 83  ILE A H    1 
ATOM   1062 H HA   . ILE A 1 69  ? 22.62870  -9.92900  4.43454   0.323 20.47137  ? 83  ILE A HA   1 
ATOM   1063 H HB   . ILE A 1 69  ? 23.71668  -7.59490  3.24384   1.000 22.20980  ? 83  ILE A HB   1 
ATOM   1064 H HG12 . ILE A 1 69  ? 22.47594  -9.73557  1.88720   1.000 24.21896  ? 83  ILE A HG12 1 
ATOM   1065 H HG13 . ILE A 1 69  ? 21.64364  -8.46786  2.36220   0.780 24.21896  ? 83  ILE A HG13 1 
ATOM   1066 H HG21 . ILE A 1 69  ? 25.13347  -9.07949  2.02671   1.000 23.91571  ? 83  ILE A HG21 1 
ATOM   1067 H HG22 . ILE A 1 69  ? 25.52378  -8.89964  3.55603   1.000 23.91571  ? 83  ILE A HG22 1 
ATOM   1068 H HG23 . ILE A 1 69  ? 24.74636  -10.20152 3.08250   0.050 23.91571  ? 83  ILE A HG23 1 
ATOM   1069 H HD11 . ILE A 1 69  ? 22.13477  -8.24771  0.13628   0.446 26.35267  ? 83  ILE A HD11 1 
ATOM   1070 H HD12 . ILE A 1 69  ? 22.92171  -7.12910  0.94432   1.000 26.35267  ? 83  ILE A HD12 1 
ATOM   1071 H HD13 . ILE A 1 69  ? 23.68462  -8.42628  0.43559   1.000 26.35267  ? 83  ILE A HD13 1 
ATOM   1072 N N    . PRO A 1 70  ? 24.46032  -10.02769 6.15242   1.000 18.15737  ? 84  PRO A N    1 
ATOM   1073 C CA   . PRO A 1 70  ? 25.30492  -9.96639  7.35250   1.000 19.33168  ? 84  PRO A CA   1 
ATOM   1074 C C    . PRO A 1 70  ? 26.57896  -9.16704  7.13610   1.000 19.18506  ? 84  PRO A C    1 
ATOM   1075 O O    . PRO A 1 70  ? 27.03635  -8.94095  6.01287   1.000 19.73337  ? 84  PRO A O    1 
ATOM   1076 C CB   . PRO A 1 70  ? 25.64468  -11.43628 7.63316   1.000 20.53300  ? 84  PRO A CB   1 
ATOM   1077 C CG   . PRO A 1 70  ? 24.59518  -12.21399 6.91830   1.000 21.85222  ? 84  PRO A CG   1 
ATOM   1078 C CD   . PRO A 1 70  ? 24.22425  -11.41636 5.71998   1.000 20.12108  ? 84  PRO A CD   1 
ATOM   1079 H HA   . PRO A 1 70  ? 24.79812  -9.58247  8.08506   0.430 23.19291  ? 84  PRO A HA   1 
ATOM   1080 H HB2  . PRO A 1 70  ? 26.52698  -11.64358 7.28752   1.000 24.63449  ? 84  PRO A HB2  1 
ATOM   1081 H HB3  . PRO A 1 70  ? 25.61388  -11.60640 8.58763   1.000 24.63449  ? 84  PRO A HB3  1 
ATOM   1082 H HG2  . PRO A 1 70  ? 24.95205  -13.07723 6.65683   1.000 26.21755  ? 84  PRO A HG2  1 
ATOM   1083 H HG3  . PRO A 1 70  ? 23.82779  -12.33442 7.49927   0.689 26.21755  ? 84  PRO A HG3  1 
ATOM   1084 H HD2  . PRO A 1 70  ? 24.78936  -11.64386 4.96513   0.358 24.14019  ? 84  PRO A HD2  1 
ATOM   1085 H HD3  . PRO A 1 70  ? 23.29195  -11.55257 5.48940   0.999 24.14019  ? 84  PRO A HD3  1 
ATOM   1086 N N    . ASP A 1 71  ? 27.17800  -8.76529  8.25058   1.000 19.69108  ? 85  ASP A N    1 
ATOM   1087 C CA   . ASP A 1 71  ? 28.50742  -8.15391  8.24289   1.000 21.07760  ? 85  ASP A CA   1 
ATOM   1088 C C    . ASP A 1 71  ? 28.50961  -6.82659  7.48617   1.000 21.45455  ? 85  ASP A C    1 
ATOM   1089 O O    . ASP A 1 71  ? 29.38614  -6.55909  6.65889   1.000 23.84517  ? 85  ASP A O    1 
ATOM   1090 C CB   . ASP A 1 71  ? 29.56422  -9.09167  7.65086   1.000 24.20526  ? 85  ASP A CB   1 
ATOM   1091 C CG   . ASP A 1 71  ? 29.60912  -10.45452 8.31825   1.000 28.76040  ? 85  ASP A CG   1 
ATOM   1092 O OD1  . ASP A 1 71  ? 29.49311  -10.54419 9.55373   1.000 29.14560  ? 85  ASP A OD1  1 
ATOM   1093 O OD2  . ASP A 1 71  ? 29.80171  -11.45082 7.58675   1.000 33.35113  ? 85  ASP A OD2  1 
ATOM   1094 H H    . ASP A 1 71  ? 26.83288  -8.83562  9.03515   1.000 23.62419  ? 85  ASP A H    1 
ATOM   1095 H HA   . ASP A 1 71  ? 28.74226  -7.97681  9.16721   1.000 25.28801  ? 85  ASP A HA   1 
ATOM   1096 H HB2  . ASP A 1 71  ? 29.36969  -9.22839  6.71045   0.748 29.04121  ? 85  ASP A HB2  1 
ATOM   1097 H HB3  . ASP A 1 71  ? 30.43787  -8.68272  7.75289   0.398 29.04121  ? 85  ASP A HB3  1 
ATOM   1098 N N    . GLY A 1 72  ? 27.51426  -5.99153  7.77014   1.000 20.98590  ? 86  GLY A N    1 
ATOM   1099 C CA   . GLY A 1 72  ? 27.48260  -4.64265  7.24075   1.000 21.43227  ? 86  GLY A CA   1 
ATOM   1100 C C    . GLY A 1 72  ? 26.91846  -4.50547  5.84544   1.000 21.55073  ? 86  GLY A C    1 
ATOM   1101 O O    . GLY A 1 72  ? 27.10870  -3.45853  5.21795   1.000 22.76480  ? 86  GLY A O    1 
ATOM   1102 H H    . GLY A 1 72  ? 26.84322  -6.18801  8.27084   0.331 25.17798  ? 86  GLY A H    1 
ATOM   1103 H HA2  . GLY A 1 72  ? 26.94339  -4.09274  7.83046   1.000 25.71362  ? 86  GLY A HA2  1 
ATOM   1104 H HA3  . GLY A 1 72  ? 28.38841  -4.29596  7.22624   0.728 25.71362  ? 86  GLY A HA3  1 
ATOM   1105 N N    . GLY A 1 73  ? 26.23318  -5.52225  5.33260   1.000 21.07957  ? 87  GLY A N    1 
ATOM   1106 C CA   . GLY A 1 73  ? 25.64871  -5.45424  4.01303   1.000 20.20012  ? 87  GLY A CA   1 
ATOM   1107 C C    . GLY A 1 73  ? 24.35920  -4.65681  3.97137   1.000 18.92257  ? 87  GLY A C    1 
ATOM   1108 O O    . GLY A 1 73  ? 23.86107  -4.13260  4.96614   1.000 19.46388  ? 87  GLY A O    1 
ATOM   1109 H H    . GLY A 1 73  ? 26.09491  -6.26762  5.73868   1.000 25.29037  ? 87  GLY A H    1 
ATOM   1110 H HA2  . GLY A 1 73  ? 26.28105  -5.03834  3.40634   0.209 24.23503  ? 87  GLY A HA2  1 
ATOM   1111 H HA3  . GLY A 1 73  ? 25.45823  -6.35341  3.70300   1.000 24.23503  ? 87  GLY A HA3  1 
ATOM   1112 N N    . SER A 1 74  ? 23.80628  -4.56635  2.77591   1.000 19.32790  ? 88  SER A N    1 
ATOM   1113 C CA   A SER A 1 74  ? 22.60291  -3.78293  2.56391   0.716 20.09369  ? 88  SER A CA   1 
ATOM   1114 C CA   B SER A 1 74  ? 22.60310  -3.78470  2.55767   0.284 19.52537  ? 88  SER A CA   1 
ATOM   1115 C C    . SER A 1 74  ? 21.37445  -4.66326  2.78038   1.000 18.13432  ? 88  SER A C    1 
ATOM   1116 O O    . SER A 1 74  ? 21.46946  -5.80690  3.23805   1.000 18.21152  ? 88  SER A O    1 
ATOM   1117 C CB   A SER A 1 74  ? 22.62983  -3.13862  1.18346   0.716 22.79799  ? 88  SER A CB   1 
ATOM   1118 C CB   B SER A 1 74  ? 22.63167  -3.16436  1.16367   0.284 21.11917  ? 88  SER A CB   1 
ATOM   1119 O OG   A SER A 1 74  ? 22.73416  -4.13003  0.18574   0.716 24.20703  ? 88  SER A OG   1 
ATOM   1120 O OG   B SER A 1 74  ? 23.86760  -2.51316  0.93063   0.284 22.07046  ? 88  SER A OG   1 
ATOM   1121 H H    . SER A 1 74  ? 24.11026  -4.95084  2.06926   0.960 23.18837  ? 88  SER A H    1 
ATOM   1122 H HA   . SER A 1 74  ? 22.57888  -3.07089  3.22218   1.000 23.42534  ? 88  SER A HA   1 
ATOM   1123 H HB2  A SER A 1 74  ? 21.81008  -2.63754  1.04992   0.716 27.35248  ? 88  SER A HB2  1 
ATOM   1124 H HB2  B SER A 1 74  ? 22.51379  -3.86493  0.50321   0.284 25.33789  ? 88  SER A HB2  1 
ATOM   1125 H HB3  A SER A 1 74  ? 23.39483  -2.54522  1.12391   0.716 27.35248  ? 88  SER A HB3  1 
ATOM   1126 H HB3  B SER A 1 74  ? 21.91389  -2.51594  1.09123   0.284 25.33789  ? 88  SER A HB3  1 
ATOM   1127 H HG   A SER A 1 74  ? 22.68242  -3.77829  -0.57531  0.716 29.04333  ? 88  SER A HG   1 
ATOM   1128 H HG   B SER A 1 74  ? 23.88152  -2.19255  0.15435   0.284 26.47945  ? 88  SER A HG   1 
ATOM   1129 N N    . GLU A 1 75  ? 20.20531  -4.12039  2.45854   1.000 17.43656  ? 89  GLU A N    1 
ATOM   1130 C CA   . GLU A 1 75  ? 18.95288  -4.81978  2.68047   1.000 16.66227  ? 89  GLU A CA   1 
ATOM   1131 C C    . GLU A 1 75  ? 18.92222  -6.11328  1.88189   1.000 17.09825  ? 89  GLU A C    1 
ATOM   1132 O O    . GLU A 1 75  ? 19.22661  -6.12662  0.68651   1.000 18.72694  ? 89  GLU A O    1 
ATOM   1133 C CB   . GLU A 1 75  ? 17.79841  -3.92623  2.24163   1.000 16.88366  ? 89  GLU A CB   1 
ATOM   1134 C CG   . GLU A 1 75  ? 17.45261  -2.79922  3.19868   1.000 17.81570  ? 89  GLU A CG   1 
ATOM   1135 C CD   . GLU A 1 75  ? 18.37367  -1.59492  3.11558   1.000 19.85948  ? 89  GLU A CD   1 
ATOM   1136 O OE1  . GLU A 1 75  ? 19.25962  -1.55991  2.23380   1.000 20.75179  ? 89  GLU A OE1  1 
ATOM   1137 O OE2  . GLU A 1 75  ? 18.19098  -0.66904  3.93993   1.000 21.17822  ? 89  GLU A OE2  1 
ATOM   1138 H H    . GLU A 1 75  ? 20.11183  -3.34101  2.10721   1.000 20.91877  ? 89  GLU A H    1 
ATOM   1139 H HA   . GLU A 1 75  ? 18.85817  -5.03302  3.62199   1.000 19.98962  ? 89  GLU A HA   1 
ATOM   1140 H HB2  . GLU A 1 75  ? 18.02996  -3.52289  1.39040   1.000 20.25528  ? 89  GLU A HB2  1 
ATOM   1141 H HB3  . GLU A 1 75  ? 17.00568  -4.47651  2.14329   0.396 20.25528  ? 89  GLU A HB3  1 
ATOM   1142 H HG2  . GLU A 1 75  ? 16.55312  -2.49308  3.00349   0.494 21.37374  ? 89  GLU A HG2  1 
ATOM   1143 H HG3  . GLU A 1 75  ? 17.49771  -3.13944  4.10594   1.000 21.37374  ? 89  GLU A HG3  1 
ATOM   1144 N N    . ILE A 1 76  ? 18.52057  -7.19745  2.53872   1.000 15.80875  ? 90  ILE A N    1 
ATOM   1145 C CA   . ILE A 1 76  ? 18.43573  -8.49008  1.87300   1.000 17.01316  ? 90  ILE A CA   1 
ATOM   1146 C C    . ILE A 1 76  ? 17.10099  -8.60605  1.15984   1.000 15.29262  ? 90  ILE A C    1 
ATOM   1147 O O    . ILE A 1 76  ? 16.10593  -7.98014  1.53367   1.000 15.50964  ? 90  ILE A O    1 
ATOM   1148 C CB   . ILE A 1 76  ? 18.62352  -9.63575  2.88503   1.000 17.84997  ? 90  ILE A CB   1 
ATOM   1149 C CG1  . ILE A 1 76  ? 19.07643  -10.91703 2.18044   1.000 18.91080  ? 90  ILE A CG1  1 
ATOM   1150 C CG2  . ILE A 1 76  ? 17.33017  -9.90115  3.65558   1.000 17.42499  ? 90  ILE A CG2  1 
ATOM   1151 C CD1  . ILE A 1 76  ? 19.60491  -11.96948 3.12807   1.000 20.93366  ? 90  ILE A CD1  1 
ATOM   1152 H H    . ILE A 1 76  ? 18.29264  -7.20924  3.36788   1.000 18.96540  ? 90  ILE A H    1 
ATOM   1153 H HA   . ILE A 1 76  ? 19.14422  -8.54719  1.21293   1.000 20.41068  ? 90  ILE A HA   1 
ATOM   1154 H HB   . ILE A 1 76  ? 19.31207  -9.36069  3.51045   1.000 21.41486  ? 90  ILE A HB   1 
ATOM   1155 H HG12 . ILE A 1 76  ? 18.32088  -11.29698 1.70539   0.701 22.68786  ? 90  ILE A HG12 1 
ATOM   1156 H HG13 . ILE A 1 76  ? 19.78475  -10.69701 1.55533   0.225 22.68786  ? 90  ILE A HG13 1 
ATOM   1157 H HG21 . ILE A 1 76  ? 17.52605  -10.47375 4.41364   1.000 20.90488  ? 90  ILE A HG21 1 
ATOM   1158 H HG22 . ILE A 1 76  ? 16.96744  -9.05616  3.96430   1.000 20.90488  ? 90  ILE A HG22 1 
ATOM   1159 H HG23 . ILE A 1 76  ? 16.69549  -10.33803 3.06632   1.000 20.90488  ? 90  ILE A HG23 1 
ATOM   1160 H HD11 . ILE A 1 76  ? 19.86172  -12.75348 2.61787   0.803 25.11528  ? 90  ILE A HD11 1 
ATOM   1161 H HD12 . ILE A 1 76  ? 20.37540  -11.61340 3.59759   1.000 25.11528  ? 90  ILE A HD12 1 
ATOM   1162 H HD13 . ILE A 1 76  ? 18.90885  -12.20119 3.76266   1.000 25.11528  ? 90  ILE A HD13 1 
ATOM   1163 N N    . GLY A 1 77  ? 17.08093  -9.42819  0.12496   1.000 15.34833  ? 91  GLY A N    1 
ATOM   1164 C CA   . GLY A 1 77  ? 15.84235  -9.84781  -0.47104  1.000 16.00223  ? 91  GLY A CA   1 
ATOM   1165 C C    . GLY A 1 77  ? 16.00126  -11.27570 -0.91829  1.000 16.55305  ? 91  GLY A C    1 
ATOM   1166 O O    . GLY A 1 77  ? 16.97278  -11.60311 -1.60988  1.000 19.04446  ? 91  GLY A O    1 
ATOM   1167 H H    . GLY A 1 77  ? 17.78185  -9.75685  -0.24960  0.694 18.41289  ? 91  GLY A H    1 
ATOM   1168 H HA2  . GLY A 1 77  ? 15.12012  -9.78845  0.17376   0.665 19.19757  ? 91  GLY A HA2  1 
ATOM   1169 H HA3  . GLY A 1 77  ? 15.62958  -9.29026  -1.23574  1.000 19.19757  ? 91  GLY A HA3  1 
ATOM   1170 N N    . TRP A 1 78  ? 15.06939  -12.13432 -0.51035  1.000 15.49600  ? 92  TRP A N    1 
ATOM   1171 C CA   . TRP A 1 78  ? 15.06569  -13.52843 -0.91426  1.000 15.80195  ? 92  TRP A CA   1 
ATOM   1172 C C    . TRP A 1 78  ? 13.68654  -13.88838 -1.44516  1.000 16.68190  ? 92  TRP A C    1 
ATOM   1173 O O    . TRP A 1 78  ? 12.75915  -13.07654 -1.43936  1.000 17.70185  ? 92  TRP A O    1 
ATOM   1174 C CB   . TRP A 1 78  ? 15.55017  -14.45969 0.20582   1.000 16.14101  ? 92  TRP A CB   1 
ATOM   1175 C CG   . TRP A 1 78  ? 14.99780  -14.21427 1.58573   1.000 15.46052  ? 92  TRP A CG   1 
ATOM   1176 C CD1  . TRP A 1 78  ? 15.61377  -13.54427 2.60494   1.000 15.34752  ? 92  TRP A CD1  1 
ATOM   1177 C CD2  . TRP A 1 78  ? 13.75332  -14.68867 2.12079   1.000 14.74437  ? 92  TRP A CD2  1 
ATOM   1178 N NE1  . TRP A 1 78  ? 14.82717  -13.55951 3.72530   1.000 14.70689  ? 92  TRP A NE1  1 
ATOM   1179 C CE2  . TRP A 1 78  ? 13.67529  -14.24968 3.45546   1.000 14.63387  ? 92  TRP A CE2  1 
ATOM   1180 C CE3  . TRP A 1 78  ? 12.69804  -15.43633 1.59656   1.000 15.42701  ? 92  TRP A CE3  1 
ATOM   1181 C CZ2  . TRP A 1 78  ? 12.58454  -14.53028 4.26779   1.000 14.30609  ? 92  TRP A CZ2  1 
ATOM   1182 C CZ3  . TRP A 1 78  ? 11.61752  -15.71315 2.39511   1.000 15.25887  ? 92  TRP A CZ3  1 
ATOM   1183 C CH2  . TRP A 1 78  ? 11.56849  -15.26806 3.72908   1.000 15.57435  ? 92  TRP A CH2  1 
ATOM   1184 H H    . TRP A 1 78  ? 14.41858  -11.92362 0.01086   0.580 18.59009  ? 92  TRP A H    1 
ATOM   1185 H HA   . TRP A 1 78  ? 15.69022  -13.65140 -1.64620  1.000 18.95723  ? 92  TRP A HA   1 
ATOM   1186 H HB2  . TRP A 1 78  ? 15.31152  -15.36823 -0.03606  1.000 19.36410  ? 92  TRP A HB2  1 
ATOM   1187 H HB3  . TRP A 1 78  ? 16.51445  -14.37558 0.26893   1.000 19.36410  ? 92  TRP A HB3  1 
ATOM   1188 H HD1  . TRP A 1 78  ? 16.44753  -13.13650 2.54600   0.808 18.41191  ? 92  TRP A HD1  1 
ATOM   1189 H HE1  . TRP A 1 78  ? 15.02475  -13.19409 4.47831   1.000 17.64316  ? 92  TRP A HE1  1 
ATOM   1190 H HE3  . TRP A 1 78  ? 12.72687  -15.74237 0.71883   1.000 18.50730  ? 92  TRP A HE3  1 
ATOM   1191 H HZ2  . TRP A 1 78  ? 12.54700  -14.22717 5.14621   1.000 17.16220  ? 92  TRP A HZ2  1 
ATOM   1192 H HZ3  . TRP A 1 78  ? 10.90631  -16.20263 2.04945   0.517 18.30554  ? 92  TRP A HZ3  1 
ATOM   1193 H HH2  . TRP A 1 78  ? 10.83061  -15.48005 4.25395   1.000 18.68411  ? 92  TRP A HH2  1 
ATOM   1194 N N    . ALA A 1 79  ? 13.56046  -15.10963 -1.94450  1.000 17.87360  ? 93  ALA A N    1 
ATOM   1195 C CA   . ALA A 1 79  ? 12.32677  -15.54957 -2.57066  1.000 17.81385  ? 93  ALA A CA   1 
ATOM   1196 C C    . ALA A 1 79  ? 11.86371  -16.83916 -1.91755  1.000 18.46567  ? 93  ALA A C    1 
ATOM   1197 O O    . ALA A 1 79  ? 12.67485  -17.65241 -1.47182  1.000 19.66722  ? 93  ALA A O    1 
ATOM   1198 C CB   . ALA A 1 79  ? 12.50665  -15.76938 -4.07897  1.000 19.37210  ? 93  ALA A CB   1 
ATOM   1199 H H    . ALA A 1 79  ? 14.18120  -15.70470 -1.93160  1.000 21.44321  ? 93  ALA A H    1 
ATOM   1200 H HA   . ALA A 1 79  ? 11.63988  -14.87654 -2.44371  1.000 21.37151  ? 93  ALA A HA   1 
ATOM   1201 H HB1  . ALA A 1 79  ? 11.66252  -16.05947 -4.45871  0.510 23.24141  ? 93  ALA A HB1  1 
ATOM   1202 H HB2  . ALA A 1 79  ? 12.78443  -14.93523 -4.48876  1.000 23.24141  ? 93  ALA A HB2  1 
ATOM   1203 H HB3  . ALA A 1 79  ? 13.18401  -16.44912 -4.22048  1.000 23.24141  ? 93  ALA A HB3  1 
ATOM   1204 N N    . VAL A 1 80  ? 10.54293  -17.02871 -1.88095  1.000 17.89777  ? 94  VAL A N    1 
ATOM   1205 C CA   . VAL A 1 80  ? 10.00571  -18.24113 -1.27777  1.000 18.43411  ? 94  VAL A CA   1 
ATOM   1206 C C    . VAL A 1 80  ? 10.38297  -19.46222 -2.08635  1.000 19.63430  ? 94  VAL A C    1 
ATOM   1207 O O    . VAL A 1 80  ? 10.41233  -20.57463 -1.54508  1.000 20.04767  ? 94  VAL A O    1 
ATOM   1208 C CB   . VAL A 1 80  ? 8.47709   -18.17005 -1.10001  1.000 17.96994  ? 94  VAL A CB   1 
ATOM   1209 C CG1  . VAL A 1 80  ? 8.09952   -16.93363 -0.29786  1.000 18.43435  ? 94  VAL A CG1  1 
ATOM   1210 C CG2  . VAL A 1 80  ? 7.75672   -18.21451 -2.45312  1.000 18.15106  ? 94  VAL A CG2  1 
ATOM   1211 H H    . VAL A 1 80  ? 9.95468   -16.48334 -2.19100  0.715 21.47222  ? 94  VAL A H    1 
ATOM   1212 H HA   . VAL A 1 80  ? 10.39033  -18.31687 -0.39050  1.000 22.11583  ? 94  VAL A HA   1 
ATOM   1213 H HB   . VAL A 1 80  ? 8.18038   -18.94816 -0.60261  1.000 21.55882  ? 94  VAL A HB   1 
ATOM   1214 H HG11 . VAL A 1 80  ? 8.83101   -16.70821 0.29797   1.000 22.11611  ? 94  VAL A HG11 1 
ATOM   1215 H HG12 . VAL A 1 80  ? 7.93264   -16.19932 -0.90929  0.335 22.11611  ? 94  VAL A HG12 1 
ATOM   1216 H HG13 . VAL A 1 80  ? 7.29980   -17.12342 0.21724   1.000 22.11611  ? 94  VAL A HG13 1 
ATOM   1217 H HG21 . VAL A 1 80  ? 6.82572   -17.97520 -2.32325  0.775 21.77616  ? 94  VAL A HG21 1 
ATOM   1218 H HG22 . VAL A 1 80  ? 8.17932   -17.58368 -3.05674  1.000 21.77616  ? 94  VAL A HG22 1 
ATOM   1219 H HG23 . VAL A 1 80  ? 7.82010   -19.11213 -2.81528  1.000 21.77616  ? 94  VAL A HG23 1 
ATOM   1220 N N    . ASP A 1 81  ? 10.68536  -19.27583 -3.37180  1.000 20.82708  ? 95  ASP A N    1 
ATOM   1221 C CA   . ASP A 1 81  ? 10.97970  -20.36701 -4.28824  1.000 22.81605  ? 95  ASP A CA   1 
ATOM   1222 C C    . ASP A 1 81  ? 12.43363  -20.35956 -4.74929  1.000 24.06494  ? 95  ASP A C    1 
ATOM   1223 O O    . ASP A 1 81  ? 12.74192  -20.93746 -5.79694  1.000 25.63798  ? 95  ASP A O    1 
ATOM   1224 C CB   . ASP A 1 81  ? 10.02179  -20.35011 -5.48768  1.000 23.48717  ? 95  ASP A CB   1 
ATOM   1225 C CG   . ASP A 1 81  ? 10.13609  -19.08311 -6.33886  1.000 24.96479  ? 95  ASP A CG   1 
ATOM   1226 O OD1  . ASP A 1 81  ? 10.54738  -18.02024 -5.82454  1.000 25.73992  ? 95  ASP A OD1  1 
ATOM   1227 O OD2  . ASP A 1 81  ? 9.78603   -19.15330 -7.53968  1.000 26.11203  ? 95  ASP A OD2  1 
ATOM   1228 H H    . ASP A 1 81  ? 10.72643  -18.50138 -3.74348  0.365 24.98739  ? 95  ASP A H    1 
ATOM   1229 H HA   . ASP A 1 81  ? 10.83050  -21.20301 -3.81949  1.000 27.37416  ? 95  ASP A HA   1 
ATOM   1230 H HB2  . ASP A 1 81  ? 10.21927  -21.10984 -6.05753  0.533 28.17950  ? 95  ASP A HB2  1 
ATOM   1231 H HB3  . ASP A 1 81  ? 9.11002   -20.40800 -5.16176  0.298 28.17950  ? 95  ASP A HB3  1 
ATOM   1232 N N    . ASP A 1 82  ? 13.34217  -19.73716 -3.98665  1.000 24.78529  ? 96  ASP A N    1 
ATOM   1233 C CA   . ASP A 1 82  ? 14.74063  -19.71566 -4.40108  1.000 25.73507  ? 96  ASP A CA   1 
ATOM   1234 C C    . ASP A 1 82  ? 15.49143  -20.98388 -4.02472  1.000 27.38402  ? 96  ASP A C    1 
ATOM   1235 O O    . ASP A 1 82  ? 16.68476  -21.09060 -4.33596  1.000 29.38870  ? 96  ASP A O    1 
ATOM   1236 C CB   . ASP A 1 82  ? 15.47940  -18.44975 -3.92192  1.000 25.54722  ? 96  ASP A CB   1 
ATOM   1237 C CG   . ASP A 1 82  ? 15.56678  -18.31729 -2.40559  1.000 25.40139  ? 96  ASP A CG   1 
ATOM   1238 O OD1  . ASP A 1 82  ? 15.32687  -19.29562 -1.66267  1.000 25.45718  ? 96  ASP A OD1  1 
ATOM   1239 O OD2  . ASP A 1 82  ? 15.89371  -17.19156 -1.95990  1.000 25.78690  ? 96  ASP A OD2  1 
ATOM   1240 H H    . ASP A 1 82  ? 13.17282  -19.33304 -3.24665  0.847 29.73724  ? 96  ASP A H    1 
ATOM   1241 H HA   . ASP A 1 82  ? 14.75798  -19.65121 -5.36878  1.000 30.87698  ? 96  ASP A HA   1 
ATOM   1242 H HB2  . ASP A 1 82  ? 16.38520  -18.46831 -4.26845  1.000 30.65155  ? 96  ASP A HB2  1 
ATOM   1243 H HB3  . ASP A 1 82  ? 15.01114  -17.67000 -4.25900  0.234 30.65155  ? 96  ASP A HB3  1 
ATOM   1244 N N    . GLY A 1 83  ? 14.81955  -21.95448 -3.40391  1.000 27.90325  ? 97  GLY A N    1 
ATOM   1245 C CA   . GLY A 1 83  ? 15.42198  -23.21900 -3.05216  1.000 28.57305  ? 97  GLY A CA   1 
ATOM   1246 C C    . GLY A 1 83  ? 16.10515  -23.24374 -1.70204  1.000 29.54708  ? 97  GLY A C    1 
ATOM   1247 O O    . GLY A 1 83  ? 16.39482  -24.33023 -1.18784  1.000 31.60222  ? 97  GLY A O    1 
ATOM   1248 H H    . GLY A 1 83  ? 13.99302  -21.89325 -3.17432  0.971 33.47880  ? 97  GLY A H    1 
ATOM   1249 H HA2  . GLY A 1 83  ? 14.73232  -23.90110 -3.04738  0.334 34.28255  ? 97  GLY A HA2  1 
ATOM   1250 H HA3  . GLY A 1 83  ? 16.08482  -23.44480 -3.72340  0.419 34.28255  ? 97  GLY A HA3  1 
ATOM   1251 N N    . THR A 1 84  ? 16.37336  -22.08469 -1.11734  1.000 27.61713  ? 98  THR A N    1 
ATOM   1252 C CA   . THR A 1 84  ? 16.97087  -21.99987 0.20404   1.000 26.60853  ? 98  THR A CA   1 
ATOM   1253 C C    . THR A 1 84  ? 15.87071  -22.04084 1.25711   1.000 24.05405  ? 98  THR A C    1 
ATOM   1254 O O    . THR A 1 84  ? 14.76342  -21.53822 1.04612   1.000 24.02069  ? 98  THR A O    1 
ATOM   1255 C CB   . THR A 1 84  ? 17.76186  -20.69448 0.32252   1.000 28.84802  ? 98  THR A CB   1 
ATOM   1256 O OG1  . THR A 1 84  ? 18.85619  -20.71562 -0.60452  1.000 31.18412  ? 98  THR A OG1  1 
ATOM   1257 C CG2  . THR A 1 84  ? 18.29083  -20.49887 1.73815   1.000 29.03927  ? 98  THR A CG2  1 
ATOM   1258 H H    . THR A 1 84  ? 16.21485  -21.31826 -1.47381  1.000 33.13545  ? 98  THR A H    1 
ATOM   1259 H HA   . THR A 1 84  ? 17.57589  -22.74180 0.36024   1.000 31.92513  ? 98  THR A HA   1 
ATOM   1260 H HB   . THR A 1 84  ? 17.17902  -19.94590 0.12047   1.000 34.61252  ? 98  THR A HB   1 
ATOM   1261 H HG1  . THR A 1 84  ? 19.25284  -21.45496 -0.56396  1.000 37.41583  ? 98  THR A HG1  1 
ATOM   1262 H HG21 . THR A 1 84  ? 18.98226  -19.81857 1.74290   1.000 34.84202  ? 98  THR A HG21 1 
ATOM   1263 H HG22 . THR A 1 84  ? 17.57107  -20.22028 2.32572   1.000 34.84202  ? 98  THR A HG22 1 
ATOM   1264 H HG23 . THR A 1 84  ? 18.66464  -21.32998 2.07043   0.636 34.84202  ? 98  THR A HG23 1 
ATOM   1265 N N    . THR A 1 85  ? 16.17536  -22.65769 2.39443   1.000 21.79084  ? 99  THR A N    1 
ATOM   1266 C CA   . THR A 1 85  ? 15.28742  -22.60493 3.54986   1.000 20.59911  ? 99  THR A CA   1 
ATOM   1267 C C    . THR A 1 85  ? 15.59656  -21.33520 4.32882   1.000 18.77679  ? 99  THR A C    1 
ATOM   1268 O O    . THR A 1 85  ? 16.73983  -21.11334 4.74066   1.000 20.38462  ? 99  THR A O    1 
ATOM   1269 C CB   . THR A 1 85  ? 15.46592  -23.81887 4.45896   1.000 22.63482  ? 99  THR A CB   1 
ATOM   1270 O OG1  . THR A 1 85  ? 15.19608  -25.01694 3.72496   1.000 24.84326  ? 99  THR A OG1  1 
ATOM   1271 C CG2  . THR A 1 85  ? 14.51711  -23.74766 5.64417   1.000 23.36025  ? 99  THR A CG2  1 
ATOM   1272 H H    . THR A 1 85  ? 16.89289  -23.11443 2.52147   1.000 26.14390  ? 99  THR A H    1 
ATOM   1273 H HA   . THR A 1 85  ? 14.36784  -22.59625 3.24133   0.601 24.71382  ? 99  THR A HA   1 
ATOM   1274 H HB   . THR A 1 85  ? 16.37741  -23.83459 4.79036   1.000 27.15668  ? 99  THR A HB   1 
ATOM   1275 H HG1  . THR A 1 85  ? 15.24290  -25.68291 4.23476   0.537 29.80680  ? 99  THR A HG1  1 
ATOM   1276 H HG21 . THR A 1 85  ? 14.85556  -23.12124 6.30291   0.182 28.02719  ? 99  THR A HG21 1 
ATOM   1277 H HG22 . THR A 1 85  ? 13.64091  -23.45286 5.35046   0.072 28.02719  ? 99  THR A HG22 1 
ATOM   1278 H HG23 . THR A 1 85  ? 14.43354  -24.62226 6.05525   1.000 28.02719  ? 99  THR A HG23 1 
ATOM   1279 N N    . HIS A 1 86  ? 14.58722  -20.50262 4.51581   1.000 16.22684  ? 100 HIS A N    1 
ATOM   1280 C CA   . HIS A 1 86  ? 14.71861  -19.27359 5.27945   1.000 15.08943  ? 100 HIS A CA   1 
ATOM   1281 C C    . HIS A 1 86  ? 14.01980  -19.48471 6.61081   1.000 14.16422  ? 100 HIS A C    1 
ATOM   1282 O O    . HIS A 1 86  ? 12.82759  -19.80030 6.64354   1.000 15.10331  ? 100 HIS A O    1 
ATOM   1283 C CB   . HIS A 1 86  ? 14.10782  -18.11631 4.49978   1.000 16.63955  ? 100 HIS A CB   1 
ATOM   1284 C CG   . HIS A 1 86  ? 14.67437  -17.98110 3.12823   1.000 19.34870  ? 100 HIS A CG   1 
ATOM   1285 N ND1  . HIS A 1 86  ? 15.82919  -17.27736 2.86968   1.000 20.46054  ? 100 HIS A ND1  1 
ATOM   1286 C CD2  . HIS A 1 86  ? 14.27274  -18.49968 1.94423   1.000 20.97534  ? 100 HIS A CD2  1 
ATOM   1287 C CE1  . HIS A 1 86  ? 16.11161  -17.36099 1.58061   1.000 21.09696  ? 100 HIS A CE1  1 
ATOM   1288 N NE2  . HIS A 1 86  ? 15.17956  -18.09305 0.99645   1.000 21.83000  ? 100 HIS A NE2  1 
ATOM   1289 H H    . HIS A 1 86  ? 13.79665  -20.63082 4.20250   1.000 19.46710  ? 100 HIS A H    1 
ATOM   1290 H HA   . HIS A 1 86  ? 15.64846  -19.06085 5.45557   0.481 18.10220  ? 100 HIS A HA   1 
ATOM   1291 H HB2  . HIS A 1 86  ? 13.15229  -18.26117 4.41683   1.000 19.96235  ? 100 HIS A HB2  1 
ATOM   1292 H HB3  . HIS A 1 86  ? 14.27777  -17.28941 4.97754   1.000 19.96235  ? 100 HIS A HB3  1 
ATOM   1293 H HD1  . HIS A 1 86  ? 16.29359  -16.85067 3.45438   1.000 24.54755  ? 100 HIS A HD1  1 
ATOM   1294 H HD2  . HIS A 1 86  ? 13.52354  -19.03140 1.79973   1.000 25.16529  ? 100 HIS A HD2  1 
ATOM   1295 H HE1  . HIS A 1 86  ? 16.84199  -16.97093 1.15718   0.082 25.31125  ? 100 HIS A HE1  1 
ATOM   1296 N N    . THR A 1 87  ? 14.75636  -19.32633 7.70132   1.000 13.66125  ? 101 THR A N    1 
ATOM   1297 C CA   . THR A 1 87  ? 14.23770  -19.63678 9.02193   1.000 13.57268  ? 101 THR A CA   1 
ATOM   1298 C C    . THR A 1 87  ? 14.45823  -18.46559 9.95583   1.000 13.23641  ? 101 THR A C    1 
ATOM   1299 O O    . THR A 1 87  ? 15.55964  -17.91732 10.01659  1.000 15.00553  ? 101 THR A O    1 
ATOM   1300 C CB   . THR A 1 87  ? 14.92129  -20.89131 9.56636   1.000 15.72673  ? 101 THR A CB   1 
ATOM   1301 O OG1  . THR A 1 87  ? 14.64558  -21.99625 8.69653   1.000 17.60538  ? 101 THR A OG1  1 
ATOM   1302 C CG2  . THR A 1 87  ? 14.43804  -21.21491 10.96320  1.000 16.73855  ? 101 THR A CG2  1 
ATOM   1303 H H    . THR A 1 87  ? 15.56650  -19.03776 7.70017   0.826 16.38840  ? 101 THR A H    1 
ATOM   1304 H HA   . THR A 1 87  ? 13.28045  -19.78595 8.97383   1.000 16.28211  ? 101 THR A HA   1 
ATOM   1305 H HB   . THR A 1 87  ? 15.87840  -20.74055 9.61236   1.000 18.86697  ? 101 THR A HB   1 
ATOM   1306 H HG1  . THR A 1 87  ? 13.81830  -22.13877 8.66650   0.107 21.12135  ? 101 THR A HG1  1 
ATOM   1307 H HG21 . THR A 1 87  ? 14.77258  -20.55554 11.59106  0.616 20.08115  ? 101 THR A HG21 1 
ATOM   1308 H HG22 . THR A 1 87  ? 13.46837  -21.20989 10.98826  1.000 20.08115  ? 101 THR A HG22 1 
ATOM   1309 H HG23 . THR A 1 87  ? 14.75528  -22.09215 11.22909  0.632 20.08115  ? 101 THR A HG23 1 
ATOM   1310 N N    . ALA A 1 88  ? 13.42977  -18.11466 10.70922  1.000 12.72862  ? 102 ALA A N    1 
ATOM   1311 C CA   . ALA A 1 88  ? 13.53911  -17.16474 11.80141  1.000 12.23093  ? 102 ALA A CA   1 
ATOM   1312 C C    . ALA A 1 88  ? 13.08786  -17.87284 13.06090  1.000 12.23121  ? 102 ALA A C    1 
ATOM   1313 O O    . ALA A 1 88  ? 12.06832  -18.56947 13.05020  1.000 13.61711  ? 102 ALA A O    1 
ATOM   1314 C CB   . ALA A 1 88  ? 12.67138  -15.93765 11.54540  1.000 13.00346  ? 102 ALA A CB   1 
ATOM   1315 H H    . ALA A 1 88  ? 12.63398  -18.42310 10.60348  1.000 15.26923  ? 102 ALA A H    1 
ATOM   1316 H HA   . ALA A 1 88  ? 14.45491  -16.86302 11.90717  1.000 14.67200  ? 102 ALA A HA   1 
ATOM   1317 H HB1  . ALA A 1 88  ? 13.03693  -15.44333 10.79513  1.000 15.59904  ? 102 ALA A HB1  1 
ATOM   1318 H HB2  . ALA A 1 88  ? 11.76789  -16.22653 11.34252  1.000 15.59904  ? 102 ALA A HB2  1 
ATOM   1319 H HB3  . ALA A 1 88  ? 12.67007  -15.38055 12.33947  1.000 15.59904  ? 102 ALA A HB3  1 
ATOM   1320 N N    . THR A 1 89  ? 13.84827  -17.71563 14.13251  1.000 11.78801  ? 103 THR A N    1 
ATOM   1321 C CA   . THR A 1 89  ? 13.47340  -18.26630 15.41676  1.000 11.97799  ? 103 THR A CA   1 
ATOM   1322 C C    . THR A 1 89  ? 13.43497  -17.14960 16.44566  1.000 11.28323  ? 103 THR A C    1 
ATOM   1323 O O    . THR A 1 89  ? 14.15496  -16.15099 16.33400  1.000 12.82136  ? 103 THR A O    1 
ATOM   1324 C CB   . THR A 1 89  ? 14.49212  -19.31730 15.87904  1.000 13.81859  ? 103 THR A CB   1 
ATOM   1325 O OG1  . THR A 1 89  ? 15.80048  -18.73214 15.91075  1.000 15.52724  ? 103 THR A OG1  1 
ATOM   1326 C CG2  . THR A 1 89  ? 14.49027  -20.52964 14.97209  1.000 15.82923  ? 103 THR A CG2  1 
ATOM   1327 H H    . THR A 1 89  ? 14.59446  -17.28811 14.13732  1.000 14.14050  ? 103 THR A H    1 
ATOM   1328 H HA   . THR A 1 89  ? 12.59767  -18.67863 15.35361  1.000 14.36847  ? 103 THR A HA   1 
ATOM   1329 H HB   . THR A 1 89  ? 14.25226  -19.62304 16.76780  1.000 16.57721  ? 103 THR A HB   1 
ATOM   1330 H HG1  . THR A 1 89  ? 16.04035  -18.52249 15.13351  1.000 18.62758  ? 103 THR A HG1  1 
ATOM   1331 H HG21 . THR A 1 89  ? 14.60385  -20.25368 14.04914  1.000 18.98997  ? 103 THR A HG21 1 
ATOM   1332 H HG22 . THR A 1 89  ? 15.21605  -21.12600 15.21394  1.000 18.98997  ? 103 THR A HG22 1 
ATOM   1333 H HG23 . THR A 1 89  ? 13.64968  -21.00619 15.05700  0.894 18.98997  ? 103 THR A HG23 1 
ATOM   1334 N N    . SER A 1 90  ? 12.61462  -17.34417 17.46821  1.000 11.14302  ? 104 SER A N    1 
ATOM   1335 C CA   . SER A 1 90  ? 12.55085  -16.37309 18.53824  1.000 10.62291  ? 104 SER A CA   1 
ATOM   1336 C C    . SER A 1 90  ? 11.98464  -17.00787 19.78672  1.000 10.77322  ? 104 SER A C    1 
ATOM   1337 O O    . SER A 1 90  ? 11.36518  -18.06913 19.75773  1.000 11.36239  ? 104 SER A O    1 
ATOM   1338 C CB   . SER A 1 90  ? 11.68620  -15.17813 18.15625  1.000 11.23166  ? 104 SER A CB   1 
ATOM   1339 O OG   . SER A 1 90  ? 10.33522  -15.59258 18.05649  1.000 11.86282  ? 104 SER A OG   1 
ATOM   1340 H H    . SER A 1 90  ? 12.09372  -18.02220 17.56057  1.000 13.36651  ? 104 SER A H    1 
ATOM   1341 H HA   . SER A 1 90  ? 13.45636  -16.08046 18.72615  1.000 12.74238  ? 104 SER A HA   1 
ATOM   1342 H HB2  . SER A 1 90  ? 11.76352  -14.49323 18.83877  1.000 13.47288  ? 104 SER A HB2  1 
ATOM   1343 H HB3  . SER A 1 90  ? 11.97992  -14.82837 17.30051  1.000 13.47288  ? 104 SER A HB3  1 
ATOM   1344 H HG   . SER A 1 90  ? 9.87328   -14.98455 17.70647  0.204 14.23028  ? 104 SER A HG   1 
ATOM   1345 N N    . SER A 1 91  ? 12.21162  -16.31883 20.89123  1.000 10.98220  ? 105 SER A N    1 
ATOM   1346 C CA   . SER A 1 91  ? 11.53373  -16.57453 22.14633  1.000 10.81678  ? 105 SER A CA   1 
ATOM   1347 C C    . SER A 1 91  ? 11.04783  -15.21737 22.60089  1.000 9.98216   ? 105 SER A C    1 
ATOM   1348 O O    . SER A 1 91  ? 11.85990  -14.30163 22.76587  1.000 10.67795  ? 105 SER A O    1 
ATOM   1349 C CB   . SER A 1 91  ? 12.49992  -17.17009 23.16459  1.000 11.77273  ? 105 SER A CB   1 
ATOM   1350 O OG   . SER A 1 91  ? 11.85757  -17.36965 24.39160  1.000 14.00258  ? 105 SER A OG   1 
ATOM   1351 H H    . SER A 1 91  ? 12.77678  -15.67241 20.93956  1.000 13.17353  ? 105 SER A H    1 
ATOM   1352 H HA   . SER A 1 91  ? 10.79293  -17.19329 22.05021  1.000 12.97502  ? 105 SER A HA   1 
ATOM   1353 H HB2  . SER A 1 91  ? 12.82353  -18.02257 22.83375  1.000 14.12217  ? 105 SER A HB2  1 
ATOM   1354 H HB3  . SER A 1 91  ? 13.24305  -16.55967 23.29130  1.000 14.12217  ? 105 SER A HB3  1 
ATOM   1355 H HG   . SER A 1 91  ? 11.20572  -17.89026 24.29332  0.154 16.79799  ? 105 SER A HG   1 
ATOM   1356 N N    . ILE A 1 92  ? 9.73797   -15.06492 22.74813  1.000 10.41842  ? 106 ILE A N    1 
ATOM   1357 C CA   . ILE A 1 92  ? 9.13119   -13.75673 22.95968  1.000 10.64595  ? 106 ILE A CA   1 
ATOM   1358 C C    . ILE A 1 92  ? 8.31734   -13.78830 24.23336  1.000 10.60829  ? 106 ILE A C    1 
ATOM   1359 O O    . ILE A 1 92  ? 7.52734   -14.70866 24.45140  1.000 11.46431  ? 106 ILE A O    1 
ATOM   1360 C CB   . ILE A 1 92  ? 8.22921   -13.35490 21.77589  1.000 11.12411  ? 106 ILE A CB   1 
ATOM   1361 C CG1  . ILE A 1 92  ? 9.00937   -13.43136 20.47292  1.000 11.49567  ? 106 ILE A CG1  1 
ATOM   1362 C CG2  . ILE A 1 92  ? 7.70788   -11.94760 21.96493  1.000 12.55607  ? 106 ILE A CG2  1 
ATOM   1363 C CD1  . ILE A 1 92  ? 8.21075   -13.11394 19.22253  1.000 11.80282  ? 106 ILE A CD1  1 
ATOM   1364 H H    . ILE A 1 92  ? 9.17285   -15.71290 22.72899  0.502 12.49699  ? 106 ILE A H    1 
ATOM   1365 H HA   . ILE A 1 92  ? 9.83815   -13.10009 23.05941  1.000 12.77003  ? 106 ILE A HA   1 
ATOM   1366 H HB   . ILE A 1 92  ? 7.48195   -13.97243 21.74178  1.000 13.34382  ? 106 ILE A HB   1 
ATOM   1367 H HG12 . ILE A 1 92  ? 9.74255   -12.79781 20.51725  1.000 13.78970  ? 106 ILE A HG12 1 
ATOM   1368 H HG13 . ILE A 1 92  ? 9.35498   -14.33242 20.37523  1.000 13.78970  ? 106 ILE A HG13 1 
ATOM   1369 H HG21 . ILE A 1 92  ? 8.45459   -11.32881 21.94457  1.000 15.06218  ? 106 ILE A HG21 1 
ATOM   1370 H HG22 . ILE A 1 92  ? 7.08788   -11.74153 21.24796  1.000 15.06218  ? 106 ILE A HG22 1 
ATOM   1371 H HG23 . ILE A 1 92  ? 7.25463   -11.89102 22.82065  1.000 15.06218  ? 106 ILE A HG23 1 
ATOM   1372 H HD11 . ILE A 1 92  ? 8.72788   -13.37207 18.44352  1.000 14.15828  ? 106 ILE A HD11 1 
ATOM   1373 H HD12 . ILE A 1 92  ? 7.37749   -13.60997 19.24562  1.000 14.15828  ? 106 ILE A HD12 1 
ATOM   1374 H HD13 . ILE A 1 92  ? 8.02822   -12.16160 19.19767  1.000 14.15828  ? 106 ILE A HD13 1 
ATOM   1375 N N    . VAL A 1 93  ? 8.46800   -12.74796 25.03845  1.000 10.95978  ? 107 VAL A N    1 
ATOM   1376 C CA   . VAL A 1 93  ? 7.58035   -12.47394 26.15701  1.000 11.87790  ? 107 VAL A CA   1 
ATOM   1377 C C    . VAL A 1 93  ? 6.72048   -11.29760 25.75414  1.000 11.54847  ? 107 VAL A C    1 
ATOM   1378 O O    . VAL A 1 93  ? 7.21940   -10.18589 25.55221  1.000 12.39271  ? 107 VAL A O    1 
ATOM   1379 C CB   . VAL A 1 93  ? 8.33511   -12.16854 27.45309  1.000 13.46010  ? 107 VAL A CB   1 
ATOM   1380 C CG1  . VAL A 1 93  ? 7.33851   -11.77975 28.53396  1.000 14.86470  ? 107 VAL A CG1  1 
ATOM   1381 C CG2  . VAL A 1 93  ? 9.16305   -13.35363 27.87020  1.000 14.12131  ? 107 VAL A CG2  1 
ATOM   1382 H H    . VAL A 1 93  ? 9.09748   -12.16812 24.95391  1.000 13.14663  ? 107 VAL A H    1 
ATOM   1383 H HA   . VAL A 1 93  ? 7.02152   -13.25153 26.31180  1.000 14.24837  ? 107 VAL A HA   1 
ATOM   1384 H HB   . VAL A 1 93  ? 8.94436   -11.42631 27.31594  1.000 16.14702  ? 107 VAL A HB   1 
ATOM   1385 H HG11 . VAL A 1 93  ? 7.78880   -11.77879 29.39311  1.000 17.83253  ? 107 VAL A HG11 1 
ATOM   1386 H HG12 . VAL A 1 93  ? 6.99257   -10.89435 28.34082  1.000 17.83253  ? 107 VAL A HG12 1 
ATOM   1387 H HG13 . VAL A 1 93  ? 6.61330   -12.42388 28.54131  1.000 17.83253  ? 107 VAL A HG13 1 
ATOM   1388 H HG21 . VAL A 1 93  ? 9.77462   -13.58006 27.15214  1.000 16.94046  ? 107 VAL A HG21 1 
ATOM   1389 H HG22 . VAL A 1 93  ? 9.66209   -13.12450 28.66981  1.000 16.94046  ? 107 VAL A HG22 1 
ATOM   1390 H HG23 . VAL A 1 93  ? 8.57377   -14.10253 28.05131  1.000 16.94046  ? 107 VAL A HG23 1 
ATOM   1391 N N    . VAL A 1 94  ? 5.42469   -11.54576 25.62450  1.000 11.78787  ? 108 VAL A N    1 
ATOM   1392 C CA   . VAL A 1 94  ? 4.45259   -10.49413 25.35784  1.000 12.26713  ? 108 VAL A CA   1 
ATOM   1393 C C    . VAL A 1 94  ? 3.81994   -10.13717 26.69585  1.000 13.13390  ? 108 VAL A C    1 
ATOM   1394 O O    . VAL A 1 94  ? 3.03813   -10.94150 27.23164  1.000 14.02914  ? 108 VAL A O    1 
ATOM   1395 C CB   . VAL A 1 94  ? 3.38974   -10.92841 24.34323  1.000 13.36322  ? 108 VAL A CB   1 
ATOM   1396 C CG1  . VAL A 1 94  ? 2.43722   -9.76446  24.06577  1.000 14.37174  ? 108 VAL A CG1  1 
ATOM   1397 C CG2  . VAL A 1 94  ? 4.03275   -11.41210 23.04769  1.000 14.18913  ? 108 VAL A CG2  1 
ATOM   1398 H H    . VAL A 1 94  ? 5.07750   -12.32999 25.68799  1.000 14.14033  ? 108 VAL A H    1 
ATOM   1399 H HA   . VAL A 1 94  ? 4.90527   -9.71700  24.99444  1.000 14.71545  ? 108 VAL A HA   1 
ATOM   1400 H HB   . VAL A 1 94  ? 2.88463   -11.66927 24.71323  0.929 16.03076  ? 108 VAL A HB   1 
ATOM   1401 H HG11 . VAL A 1 94  ? 1.99985   -9.51015  24.89337  1.000 17.24098  ? 108 VAL A HG11 1 
ATOM   1402 H HG12 . VAL A 1 94  ? 2.94630   -9.01601  23.71712  1.000 17.24098  ? 108 VAL A HG12 1 
ATOM   1403 H HG13 . VAL A 1 94  ? 1.77546   -10.04621 23.41493  0.712 17.24098  ? 108 VAL A HG13 1 
ATOM   1404 H HG21 . VAL A 1 94  ? 4.82605   -10.88232 22.87188  1.000 17.02185  ? 108 VAL A HG21 1 
ATOM   1405 H HG22 . VAL A 1 94  ? 4.27387   -12.34665 23.14452  1.000 17.02185  ? 108 VAL A HG22 1 
ATOM   1406 H HG23 . VAL A 1 94  ? 3.39778   -11.30780 22.32185  0.397 17.02185  ? 108 VAL A HG23 1 
ATOM   1407 N N    A PRO A 1 95  ? 4.15156   -8.99240  27.28725  1.000 13.89587  ? 109 PRO A N    1 
ATOM   1408 N N    B PRO A 1 95  ? 4.15749   -9.00027  27.29530  0.000 14.73440  ? 109 PRO A N    1 
ATOM   1409 C CA   A PRO A 1 95  ? 3.47697   -8.57800  28.51549  1.000 14.96159  ? 109 PRO A CA   1 
ATOM   1410 C CA   B PRO A 1 95  ? 3.47610   -8.60191  28.52617  0.000 15.67995  ? 109 PRO A CA   1 
ATOM   1411 C C    A PRO A 1 95  ? 2.03869   -8.20780  28.20818  1.000 15.21340  ? 109 PRO A C    1 
ATOM   1412 C C    B PRO A 1 95  ? 2.06263   -8.14231  28.21639  0.000 16.10086  ? 109 PRO A C    1 
ATOM   1413 O O    A PRO A 1 95  ? 1.64188   -8.04380  27.05679  1.000 14.58237  ? 109 PRO A O    1 
ATOM   1414 O O    B PRO A 1 95  ? 1.70447   -7.86916  27.06867  0.000 16.06122  ? 109 PRO A O    1 
ATOM   1415 C CB   A PRO A 1 95  ? 4.28196   -7.35678  28.96993  1.000 16.42764  ? 109 PRO A CB   1 
ATOM   1416 C CB   B PRO A 1 95  ? 4.33494   -7.44783  29.05265  0.000 16.07573  ? 109 PRO A CB   1 
ATOM   1417 C CG   A PRO A 1 95  ? 4.92529   -6.84168  27.77325  1.000 18.02598  ? 109 PRO A CG   1 
ATOM   1418 C CG   B PRO A 1 95  ? 4.97907   -6.87842  27.84581  0.000 16.15435  ? 109 PRO A CG   1 
ATOM   1419 C CD   A PRO A 1 95  ? 5.10190   -7.97411  26.81031  1.000 15.13442  ? 109 PRO A CD   1 
ATOM   1420 C CD   B PRO A 1 95  ? 5.17226   -8.01463  26.88083  0.000 15.49470  ? 109 PRO A CD   1 
ATOM   1421 H HA   A PRO A 1 95  ? 3.51745   -9.26263  29.20146  1.000 17.94880  ? 109 PRO A HA   1 
ATOM   1422 H HA   B PRO A 1 95  ? 3.46531   -9.31678  29.18173  0.000 18.81083  ? 109 PRO A HA   1 
ATOM   1423 H HB2  A PRO A 1 95  ? 3.68464   -6.69487  29.35200  1.000 19.70806  ? 109 PRO A HB2  1 
ATOM   1424 H HB2  B PRO A 1 95  ? 3.77311   -6.78970  29.49096  0.000 19.28577  ? 109 PRO A HB2  1 
ATOM   1425 H HB3  A PRO A 1 95  ? 4.94241   -7.62637  29.62722  1.000 19.70806  ? 109 PRO A HB3  1 
ATOM   1426 H HB3  B PRO A 1 95  ? 4.99804   -7.78523  29.67503  0.000 19.28577  ? 109 PRO A HB3  1 
ATOM   1427 H HG2  A PRO A 1 95  ? 4.36356   -6.15443  27.38204  1.000 21.62607  ? 109 PRO A HG2  1 
ATOM   1428 H HG2  B PRO A 1 95  ? 4.40260   -6.19970  27.46121  0.000 19.38012  ? 109 PRO A HG2  1 
ATOM   1429 H HG3  A PRO A 1 95  ? 5.78803   -6.46850  28.01264  1.000 21.62607  ? 109 PRO A HG3  1 
ATOM   1430 H HG3  B PRO A 1 95  ? 5.83374   -6.48912  28.08850  0.000 19.38012  ? 109 PRO A HG3  1 
ATOM   1431 H HD2  A PRO A 1 95  ? 4.88157   -7.69486  25.90788  1.000 18.15620  ? 109 PRO A HD2  1 
ATOM   1432 H HD2  B PRO A 1 95  ? 5.01524   -7.72207  25.96943  0.000 18.58853  ? 109 PRO A HD2  1 
ATOM   1433 H HD3  A PRO A 1 95  ? 6.01071   -8.31183  26.84053  1.000 18.15620  ? 109 PRO A HD3  1 
ATOM   1434 H HD3  B PRO A 1 95  ? 6.06486   -8.38575  26.96101  0.000 18.58853  ? 109 PRO A HD3  1 
ATOM   1435 N N    . GLU A 1 96  ? 1.24773   -8.06944  29.26281  1.000 16.54509  ? 110 GLU A N    1 
ATOM   1436 C CA   . GLU A 1 96  ? -0.08173  -7.51449  29.10609  1.000 19.00895  ? 110 GLU A CA   1 
ATOM   1437 C C    . GLU A 1 96  ? 0.06618   -6.11851  28.51816  1.000 17.97987  ? 110 GLU A C    1 
ATOM   1438 O O    . GLU A 1 96  ? 0.87583   -5.31759  28.99009  1.000 19.54119  ? 110 GLU A O    1 
ATOM   1439 C CB   . GLU A 1 96  ? -0.75773  -7.44995  30.47121  1.000 24.69481  ? 110 GLU A CB   1 
ATOM   1440 C CG   . GLU A 1 96  ? -2.27279  -7.44542  30.42556  1.000 32.32593  ? 110 GLU A CG   1 
ATOM   1441 C CD   . GLU A 1 96  ? -2.90003  -7.92260  31.72884  1.000 38.87124  ? 110 GLU A CD   1 
ATOM   1442 O OE1  . GLU A 1 96  ? -2.17481  -8.50348  32.57422  1.000 41.25243  ? 110 GLU A OE1  1 
ATOM   1443 O OE2  . GLU A 1 96  ? -4.12360  -7.72467  31.90250  1.000 41.34352  ? 110 GLU A OE2  1 
ATOM   1444 H H    . GLU A 1 96  ? 1.45830   -8.28767  30.06756  0.707 19.84900  ? 110 GLU A H    1 
ATOM   1445 H HA   . GLU A 1 96  ? -0.63438  -8.05846  28.52336  1.000 22.80563  ? 110 GLU A HA   1 
ATOM   1446 H HB2  . GLU A 1 96  ? -0.48297  -8.22321  30.98840  1.000 29.62867  ? 110 GLU A HB2  1 
ATOM   1447 H HB3  . GLU A 1 96  ? -0.47606  -6.63568  30.91677  1.000 29.62867  ? 110 GLU A HB3  1 
ATOM   1448 H HG2  . GLU A 1 96  ? -2.58169  -6.54155  30.25674  0.010 38.78601  ? 110 GLU A HG2  1 
ATOM   1449 H HG3  . GLU A 1 96  ? -2.56985  -8.03561  29.71540  1.000 38.78601  ? 110 GLU A HG3  1 
ATOM   1450 N N    . GLN A 1 97  ? -0.66149  -5.84469  27.44518  1.000 16.95600  ? 111 GLN A N    1 
ATOM   1451 C CA   . GLN A 1 97  ? -0.52818  -4.57077  26.75853  1.000 16.65567  ? 111 GLN A CA   1 
ATOM   1452 C C    . GLN A 1 97  ? -1.45120  -3.53708  27.37414  1.000 17.66025  ? 111 GLN A C    1 
ATOM   1453 O O    . GLN A 1 97  ? -2.55060  -3.85164  27.83113  1.000 19.18881  ? 111 GLN A O    1 
ATOM   1454 C CB   . GLN A 1 97  ? -0.83782  -4.71916  25.27244  1.000 15.85520  ? 111 GLN A CB   1 
ATOM   1455 C CG   . GLN A 1 97  ? 0.09428   -5.67245  24.56475  1.000 14.72894  ? 111 GLN A CG   1 
ATOM   1456 C CD   . GLN A 1 97  ? 1.53313   -5.18555  24.58727  1.000 14.08164  ? 111 GLN A CD   1 
ATOM   1457 O OE1  . GLN A 1 97  ? 1.83289   -4.08659  24.11182  1.000 14.99673  ? 111 GLN A OE1  1 
ATOM   1458 N NE2  . GLN A 1 97  ? 2.43450   -6.00043  25.13523  1.000 14.52692  ? 111 GLN A NE2  1 
ATOM   1459 H H    . GLN A 1 97  ? -1.23783  -6.37950  27.09674  1.000 20.34209  ? 111 GLN A H    1 
ATOM   1460 H HA   . GLN A 1 97  ? 0.38520   -4.25602  26.84556  1.000 19.98170  ? 111 GLN A HA   1 
ATOM   1461 H HB2  . GLN A 1 97  ? -1.74204  -5.05559  25.17196  1.000 19.02113  ? 111 GLN A HB2  1 
ATOM   1462 H HB3  . GLN A 1 97  ? -0.75748  -3.85136  24.84657  1.000 19.02113  ? 111 GLN A HB3  1 
ATOM   1463 H HG2  . GLN A 1 97  ? 0.06005   -6.53668  25.00388  1.000 17.66962  ? 111 GLN A HG2  1 
ATOM   1464 H HG3  . GLN A 1 97  ? -0.18155  -5.75960  23.63889  1.000 17.66962  ? 111 GLN A HG3  1 
ATOM   1465 H HE21 . GLN A 1 97  ? 2.18933   -6.76054  25.45417  1.000 17.42719  ? 111 GLN A HE21 1 
ATOM   1466 H HE22 . GLN A 1 97  ? 3.26123   -5.76607  25.16981  1.000 17.42719  ? 111 GLN A HE22 1 
ATOM   1467 N N    . VAL A 1 98  ? -0.98245  -2.29059  27.39037  1.000 18.15858  ? 112 VAL A N    1 
ATOM   1468 C CA   . VAL A 1 98  ? -1.75364  -1.23311  28.02398  1.000 19.71149  ? 112 VAL A CA   1 
ATOM   1469 C C    . VAL A 1 98  ? -2.99509  -0.91507  27.20319  1.000 20.10267  ? 112 VAL A C    1 
ATOM   1470 O O    . VAL A 1 98  ? -3.08171  -1.19910  26.00315  1.000 19.33474  ? 112 VAL A O    1 
ATOM   1471 C CB   . VAL A 1 98  ? -0.90576  0.02514   28.26770  1.000 21.44519  ? 112 VAL A CB   1 
ATOM   1472 C CG1  . VAL A 1 98  ? 0.31310   -0.31930  29.09487  1.000 22.06352  ? 112 VAL A CG1  1 
ATOM   1473 C CG2  . VAL A 1 98  ? -0.51315  0.68290   26.96228  1.000 21.16725  ? 112 VAL A CG2  1 
ATOM   1474 H H    . VAL A 1 98  ? -0.23510  -2.03838  27.04764  1.000 21.78519  ? 112 VAL A H    1 
ATOM   1475 H HA   . VAL A 1 98  ? -2.04640  -1.55607  28.89051  1.000 23.64868  ? 112 VAL A HA   1 
ATOM   1476 H HB   . VAL A 1 98  ? -1.43663  0.66844   28.76292  1.000 25.72912  ? 112 VAL A HB   1 
ATOM   1477 H HG11 . VAL A 1 98  ? 0.15226   -1.15420  29.56175  0.048 26.47111  ? 112 VAL A HG11 1 
ATOM   1478 H HG12 . VAL A 1 98  ? 1.07848   -0.41165  28.50617  1.000 26.47111  ? 112 VAL A HG12 1 
ATOM   1479 H HG13 . VAL A 1 98  ? 0.47189   0.39222   29.73473  0.034 26.47111  ? 112 VAL A HG13 1 
ATOM   1480 H HG21 . VAL A 1 98  ? 0.15891   1.35960   27.13921  0.918 25.39559  ? 112 VAL A HG21 1 
ATOM   1481 H HG22 . VAL A 1 98  ? -0.15427  0.00868   26.36434  1.000 25.39559  ? 112 VAL A HG22 1 
ATOM   1482 H HG23 . VAL A 1 98  ? -1.29835  1.09213   26.56617  1.000 25.39559  ? 112 VAL A HG23 1 
ATOM   1483 N N    . ASP A 1 99  ? -3.96705  -0.29838  27.87092  1.000 21.79977  ? 113 ASP A N    1 
ATOM   1484 C CA   . ASP A 1 99  ? -5.18626  0.11528   27.19845  1.000 23.17223  ? 113 ASP A CA   1 
ATOM   1485 C C    . ASP A 1 99  ? -4.84375  1.02179   26.02998  1.000 21.72116  ? 113 ASP A C    1 
ATOM   1486 O O    . ASP A 1 99  ? -3.99926  1.91465   26.14370  1.000 23.13304  ? 113 ASP A O    1 
ATOM   1487 C CB   . ASP A 1 99  ? -6.07305  0.89338   28.16710  1.000 27.44154  ? 113 ASP A CB   1 
ATOM   1488 C CG   . ASP A 1 99  ? -6.70589  0.01202   29.23171  1.000 32.61678  ? 113 ASP A CG   1 
ATOM   1489 O OD1  . ASP A 1 99  ? -6.73895  -1.22709  29.04849  1.000 34.21154  ? 113 ASP A OD1  1 
ATOM   1490 O OD2  . ASP A 1 99  ? -7.18706  0.57129   30.24669  1.000 35.26073  ? 113 ASP A OD2  1 
ATOM   1491 H H    . ASP A 1 99  ? -3.94235  -0.11010  28.70970  1.000 26.15462  ? 113 ASP A H    1 
ATOM   1492 H HA   . ASP A 1 99  ? -5.66384  -0.66716  26.88126  0.515 27.80156  ? 113 ASP A HA   1 
ATOM   1493 H HB2  . ASP A 1 99  ? -5.53608  1.56520   28.61569  0.415 32.92475  ? 113 ASP A HB2  1 
ATOM   1494 H HB3  . ASP A 1 99  ? -6.78759  1.31887   27.66782  0.600 32.92475  ? 113 ASP A HB3  1 
ATOM   1495 N N    . GLY A 1 100 ? -5.51830  0.79939   24.90466  1.000 20.80208  ? 114 GLY A N    1 
ATOM   1496 C CA   . GLY A 1 100 ? -5.27905  1.55151   23.70119  1.000 20.11258  ? 114 GLY A CA   1 
ATOM   1497 C C    . GLY A 1 100 ? -4.45107  0.81688   22.67434  1.000 18.88513  ? 114 GLY A C    1 
ATOM   1498 O O    . GLY A 1 100 ? -4.52449  1.14153   21.48317  1.000 19.27305  ? 114 GLY A O    1 
ATOM   1499 H H    . GLY A 1 100 ? -6.13141  0.20189   24.82291  0.165 24.95739  ? 114 GLY A H    1 
ATOM   1500 H HA2  . GLY A 1 100 ? -6.13129  1.77448   23.29514  1.000 24.12999  ? 114 GLY A HA2  1 
ATOM   1501 H HA3  . GLY A 1 100 ? -4.81414  2.37148   23.93009  1.000 24.12999  ? 114 GLY A HA3  1 
ATOM   1502 N N    . VAL A 1 101 ? -3.66177  -0.15817  23.10469  1.000 16.99618  ? 115 VAL A N    1 
ATOM   1503 C CA   . VAL A 1 101 ? -2.93629  -1.03116  22.19164  1.000 16.37792  ? 115 VAL A CA   1 
ATOM   1504 C C    . VAL A 1 101 ? -3.85861  -2.18666  21.83005  1.000 16.07238  ? 115 VAL A C    1 
ATOM   1505 O O    . VAL A 1 101 ? -4.36288  -2.89157  22.71171  1.000 17.66085  ? 115 VAL A O    1 
ATOM   1506 C CB   . VAL A 1 101 ? -1.62959  -1.53664  22.83301  1.000 15.84295  ? 115 VAL A CB   1 
ATOM   1507 C CG1  . VAL A 1 101 ? -0.89639  -2.45724  21.85878  1.000 14.94115  ? 115 VAL A CG1  1 
ATOM   1508 C CG2  . VAL A 1 101 ? -0.75023  -0.36047  23.24408  1.000 17.04266  ? 115 VAL A CG2  1 
ATOM   1509 H H    . VAL A 1 101 ? -3.52757  -0.33740  23.93503  1.000 20.39031  ? 115 VAL A H    1 
ATOM   1510 H HA   . VAL A 1 101 ? -2.70184  -0.54876  21.38342  1.000 19.64840  ? 115 VAL A HA   1 
ATOM   1511 H HB   . VAL A 1 101 ? -1.83576  -2.04410  23.63356  1.000 19.00643  ? 115 VAL A HB   1 
ATOM   1512 H HG11 . VAL A 1 101 ? -0.02021  -2.66509  22.21935  0.778 17.92427  ? 115 VAL A HG11 1 
ATOM   1513 H HG12 . VAL A 1 101 ? -1.41009  -3.27246  21.74727  1.000 17.92427  ? 115 VAL A HG12 1 
ATOM   1514 H HG13 . VAL A 1 101 ? -0.80421  -2.00504  21.00560  1.000 17.92427  ? 115 VAL A HG13 1 
ATOM   1515 H HG21 . VAL A 1 101 ? -0.93682  0.39217   22.66132  0.115 20.44608  ? 115 VAL A HG21 1 
ATOM   1516 H HG22 . VAL A 1 101 ? -0.94872  -0.12399  24.16363  1.000 20.44608  ? 115 VAL A HG22 1 
ATOM   1517 H HG23 . VAL A 1 101 ? 0.18116   -0.61891  23.16267  1.000 20.44608  ? 115 VAL A HG23 1 
ATOM   1518 N N    . GLU A 1 102 ? -4.06247  -2.39181  20.53122  1.000 15.34026  ? 116 GLU A N    1 
ATOM   1519 C CA   . GLU A 1 102 ? -5.03269  -3.35195  20.01917  1.000 16.30158  ? 116 GLU A CA   1 
ATOM   1520 C C    . GLU A 1 102 ? -4.41005  -4.49676  19.23338  1.000 15.06745  ? 116 GLU A C    1 
ATOM   1521 O O    . GLU A 1 102 ? -4.97588  -5.59886  19.22443  1.000 15.67139  ? 116 GLU A O    1 
ATOM   1522 C CB   . GLU A 1 102 ? -6.03761  -2.63971  19.10352  1.000 19.32405  ? 116 GLU A CB   1 
ATOM   1523 C CG   . GLU A 1 102 ? -6.73758  -1.45296  19.73824  1.000 23.86362  ? 116 GLU A CG   1 
ATOM   1524 C CD   . GLU A 1 102 ? -7.46456  -1.79948  21.02184  1.000 29.59017  ? 116 GLU A CD   1 
ATOM   1525 O OE1  . GLU A 1 102 ? -7.89090  -2.96332  21.17231  1.000 32.15276  ? 116 GLU A OE1  1 
ATOM   1526 O OE2  . GLU A 1 102 ? -7.62454  -0.89202  21.87487  1.000 32.58187  ? 116 GLU A OE2  1 
ATOM   1527 H H    . GLU A 1 102 ? -3.63833  -1.97448  19.91030  1.000 18.40320  ? 116 GLU A H    1 
ATOM   1528 H HA   . GLU A 1 102 ? -5.51273  -3.73408  20.77047  1.000 19.55679  ? 116 GLU A HA   1 
ATOM   1529 H HB2  . GLU A 1 102 ? -5.56604  -2.31662  18.31986  1.000 23.18375  ? 116 GLU A HB2  1 
ATOM   1530 H HB3  . GLU A 1 102 ? -6.72072  -3.27623  18.84068  1.000 23.18375  ? 116 GLU A HB3  1 
ATOM   1531 H HG2  . GLU A 1 102 ? -6.07732  -0.77304  19.94480  1.000 28.63123  ? 116 GLU A HG2  1 
ATOM   1532 H HG3  . GLU A 1 102 ? -7.39033  -1.10223  19.11230  1.000 28.63123  ? 116 GLU A HG3  1 
ATOM   1533 N N    . GLU A 1 103 ? -3.28108  -4.26797  18.55973  1.000 14.46125  ? 117 GLU A N    1 
ATOM   1534 C CA   . GLU A 1 103 ? -2.62505  -5.29697  17.76745  1.000 13.65900  ? 117 GLU A CA   1 
ATOM   1535 C C    . GLU A 1 103 ? -1.17101  -4.88621  17.64323  1.000 12.32391  ? 117 GLU A C    1 
ATOM   1536 O O    . GLU A 1 103 ? -0.88914  -3.72789  17.32999  1.000 13.42978  ? 117 GLU A O    1 
ATOM   1537 C CB   . GLU A 1 103 ? -3.25109  -5.46392  16.36216  1.000 14.92584  ? 117 GLU A CB   1 
ATOM   1538 C CG   . GLU A 1 103 ? -2.46990  -6.51571  15.55054  1.000 15.78612  ? 117 GLU A CG   1 
ATOM   1539 C CD   . GLU A 1 103 ? -3.03475  -6.84866  14.17908  1.000 17.44887  ? 117 GLU A CD   1 
ATOM   1540 O OE1  . GLU A 1 103 ? -3.89377  -6.10126  13.66281  1.000 19.35686  ? 117 GLU A OE1  1 
ATOM   1541 O OE2  . GLU A 1 103 ? -2.60711  -7.87737  13.60232  1.000 17.01201  ? 117 GLU A OE2  1 
ATOM   1542 H H    . GLU A 1 103 ? -2.87216  -3.51150  18.54810  1.000 17.34840  ? 117 GLU A H    1 
ATOM   1543 H HA   . GLU A 1 103 ? -2.70531  -6.15434  18.21396  1.000 16.38569  ? 117 GLU A HA   1 
ATOM   1544 H HB2  . GLU A 1 103 ? -4.17105  -5.75893  16.44905  1.000 17.90590  ? 117 GLU A HB2  1 
ATOM   1545 H HB3  . GLU A 1 103 ? -3.21725  -4.61805  15.88861  1.000 17.90590  ? 117 GLU A HB3  1 
ATOM   1546 H HG2  . GLU A 1 103 ? -1.56704  -6.18736  15.41666  1.000 18.93823  ? 117 GLU A HG2  1 
ATOM   1547 H HG3  . GLU A 1 103 ? -2.45072  -7.34057  16.06058  1.000 18.93823  ? 117 GLU A HG3  1 
ATOM   1548 N N    . VAL A 1 104 ? -0.25493  -5.81813  17.88529  1.000 11.29944  ? 118 VAL A N    1 
ATOM   1549 C CA   . VAL A 1 104 ? 1.17203   -5.54215  17.75499  1.000 11.55910  ? 118 VAL A CA   1 
ATOM   1550 C C    . VAL A 1 104 ? 1.79420   -6.64909  16.92764  1.000 10.45284  ? 118 VAL A C    1 
ATOM   1551 O O    . VAL A 1 104 ? 1.78948   -7.81147  17.33356  1.000 10.87306  ? 118 VAL A O    1 
ATOM   1552 C CB   . VAL A 1 104 ? 1.89472   -5.42833  19.10496  1.000 11.49054  ? 118 VAL A CB   1 
ATOM   1553 C CG1  . VAL A 1 104 ? 3.33854   -5.03270  18.88404  1.000 11.74619  ? 118 VAL A CG1  1 
ATOM   1554 C CG2  . VAL A 1 104 ? 1.20104   -4.43644  19.99285  1.000 12.46140  ? 118 VAL A CG2  1 
ATOM   1555 H H    . VAL A 1 104 ? -0.43688  -6.62288  18.12791  0.924 13.55422  ? 118 VAL A H    1 
ATOM   1556 H HA   . VAL A 1 104 ? 1.27435   -4.69862  17.28714  1.000 13.86581  ? 118 VAL A HA   1 
ATOM   1557 H HB   . VAL A 1 104 ? 1.87629   -6.28921  19.55156  1.000 13.78354  ? 118 VAL A HB   1 
ATOM   1558 H HG11 . VAL A 1 104 ? 3.37116   -4.29511  18.25492  1.000 14.09032  ? 118 VAL A HG11 1 
ATOM   1559 H HG12 . VAL A 1 104 ? 3.72501   -4.76193  19.73153  0.447 14.09032  ? 118 VAL A HG12 1 
ATOM   1560 H HG13 . VAL A 1 104 ? 3.82340   -5.79336  18.52737  1.000 14.09032  ? 118 VAL A HG13 1 
ATOM   1561 H HG21 . VAL A 1 104 ? 0.25530   -4.64944  20.02585  1.000 14.94858  ? 118 VAL A HG21 1 
ATOM   1562 H HG22 . VAL A 1 104 ? 1.58301   -4.48817  20.88298  1.000 14.94858  ? 118 VAL A HG22 1 
ATOM   1563 H HG23 . VAL A 1 104 ? 1.32703   -3.54568  19.63010  1.000 14.94858  ? 118 VAL A HG23 1 
ATOM   1564 N N    . THR A 1 105 ? 2.30662   -6.29930  15.76150  1.000 10.21125  ? 119 THR A N    1 
ATOM   1565 C CA   . THR A 1 105 ? 3.01243   -7.26601  14.93452  1.000 10.17227  ? 119 THR A CA   1 
ATOM   1566 C C    . THR A 1 105 ? 4.42269   -7.44058  15.48066  1.000 10.25503  ? 119 THR A C    1 
ATOM   1567 O O    . THR A 1 105 ? 5.14564   -6.45752  15.67567  1.000 10.92059  ? 119 THR A O    1 
ATOM   1568 C CB   . THR A 1 105 ? 3.03384   -6.77508  13.49106  1.000 11.12595  ? 119 THR A CB   1 
ATOM   1569 O OG1  . THR A 1 105 ? 1.70164   -6.75196  12.98967  1.000 12.36040  ? 119 THR A OG1  1 
ATOM   1570 C CG2  . THR A 1 105 ? 3.85622   -7.68896  12.59861  1.000 11.82502  ? 119 THR A CG2  1 
ATOM   1571 H H    . THR A 1 105 ? 2.26045   -5.50936  15.42467  1.000 12.24839  ? 119 THR A H    1 
ATOM   1572 H HA   . THR A 1 105 ? 2.57230   -8.13030  14.94836  1.000 12.20162  ? 119 THR A HA   1 
ATOM   1573 H HB   . THR A 1 105 ? 3.43131   -5.89051  13.46995  1.000 13.34604  ? 119 THR A HB   1 
ATOM   1574 H HG1  . THR A 1 105 ? 1.15663   -6.68381  13.62521  0.194 14.82738  ? 119 THR A HG1  1 
ATOM   1575 H HG21 . THR A 1 105 ? 3.60230   -8.61339  12.74651  1.000 14.18491  ? 119 THR A HG21 1 
ATOM   1576 H HG22 . THR A 1 105 ? 3.70521   -7.46627  11.66667  1.000 14.18491  ? 119 THR A HG22 1 
ATOM   1577 H HG23 . THR A 1 105 ? 4.79990   -7.58595  12.79797  1.000 14.18491  ? 119 THR A HG23 1 
ATOM   1578 N N    . ILE A 1 106 ? 4.79389   -8.69823  15.73536  1.000 9.54721   ? 120 ILE A N    1 
ATOM   1579 C CA   . ILE A 1 106 ? 6.02381   -9.03824  16.43135  1.000 9.46413   ? 120 ILE A CA   1 
ATOM   1580 C C    . ILE A 1 106 ? 7.02704   -9.78974  15.56939  1.000 9.41094   ? 120 ILE A C    1 
ATOM   1581 O O    . ILE A 1 106 ? 8.22186   -9.73763  15.86911  1.000 9.82528   ? 120 ILE A O    1 
ATOM   1582 C CB   . ILE A 1 106 ? 5.73413   -9.80089  17.74341  1.000 10.28637  ? 120 ILE A CB   1 
ATOM   1583 C CG1  . ILE A 1 106 ? 5.06055   -11.16272 17.49526  1.000 10.78205  ? 120 ILE A CG1  1 
ATOM   1584 C CG2  . ILE A 1 106 ? 4.90583   -8.92829  18.66754  1.000 11.56328  ? 120 ILE A CG2  1 
ATOM   1585 C CD1  . ILE A 1 106 ? 4.63883   -11.89094 18.75500  1.000 11.67827  ? 120 ILE A CD1  1 
ATOM   1586 H H    . ILE A 1 106 ? 4.33347   -9.38757  15.50638  1.000 11.45154  ? 120 ILE A H    1 
ATOM   1587 H HA   . ILE A 1 106 ? 6.46368   -8.20929  16.67681  1.000 11.35185  ? 120 ILE A HA   1 
ATOM   1588 H HB   . ILE A 1 106 ? 6.58391   -9.99670  18.16820  1.000 12.33853  ? 120 ILE A HB   1 
ATOM   1589 H HG12 . ILE A 1 106 ? 4.26537   -11.02129 16.95806  0.584 12.93335  ? 120 ILE A HG12 1 
ATOM   1590 H HG13 . ILE A 1 106 ? 5.68413   -11.73446 17.02075  1.000 12.93335  ? 120 ILE A HG13 1 
ATOM   1591 H HG21 . ILE A 1 106 ? 3.99892   -8.87938  18.32693  1.000 13.87083  ? 120 ILE A HG21 1 
ATOM   1592 H HG22 . ILE A 1 106 ? 4.90519   -9.31976  19.55504  1.000 13.87083  ? 120 ILE A HG22 1 
ATOM   1593 H HG23 . ILE A 1 106 ? 5.29613   -8.04079  18.69777  1.000 13.87083  ? 120 ILE A HG23 1 
ATOM   1594 H HD11 . ILE A 1 106 ? 5.41536   -12.01533 19.32284  0.566 14.00881  ? 120 ILE A HD11 1 
ATOM   1595 H HD12 . ILE A 1 106 ? 3.97189   -11.36036 19.21823  1.000 14.00881  ? 120 ILE A HD12 1 
ATOM   1596 H HD13 . ILE A 1 106 ? 4.26551   -12.75254 18.51174  1.000 14.00881  ? 120 ILE A HD13 1 
ATOM   1597 N N    . MET A 1 107 ? 6.59663   -10.49270 14.52399  1.000 9.97896   ? 121 MET A N    1 
ATOM   1598 C CA   . MET A 1 107 ? 7.50782   -11.04415 13.53060  1.000 10.07241  ? 121 MET A CA   1 
ATOM   1599 C C    . MET A 1 107 ? 6.82369   -10.94575 12.17897  1.000 9.76318   ? 121 MET A C    1 
ATOM   1600 O O    . MET A 1 107 ? 5.59327   -10.99260 12.09482  1.000 10.54530  ? 121 MET A O    1 
ATOM   1601 C CB   . MET A 1 107 ? 7.83811   -12.51220 13.78464  1.000 10.46722  ? 121 MET A CB   1 
ATOM   1602 C CG   . MET A 1 107 ? 8.50460   -12.77307 15.11729  1.000 11.33145  ? 121 MET A CG   1 
ATOM   1603 S SD   . MET A 1 107 ? 8.95243   -14.51107 15.36937  1.000 12.26606  ? 121 MET A SD   1 
ATOM   1604 C CE   . MET A 1 107 ? 10.46437  -14.63932 14.40698  1.000 14.14969  ? 121 MET A CE   1 
ATOM   1605 H H    . MET A 1 107 ? 5.76867   -10.66508 14.36790  1.000 11.96964  ? 121 MET A H    1 
ATOM   1606 H HA   . MET A 1 107 ? 8.33815   -10.54316 13.55167  1.000 12.08179  ? 121 MET A HA   1 
ATOM   1607 H HB2  . MET A 1 107 ? 7.01462   -13.02429 13.76163  0.327 12.55556  ? 121 MET A HB2  1 
ATOM   1608 H HB3  . MET A 1 107 ? 8.43978   -12.82006 13.08886  1.000 12.55556  ? 121 MET A HB3  1 
ATOM   1609 H HG2  . MET A 1 107 ? 9.31717   -12.24597 15.17015  1.000 13.59263  ? 121 MET A HG2  1 
ATOM   1610 H HG3  . MET A 1 107 ? 7.89607   -12.51675 15.82786  1.000 13.59263  ? 121 MET A HG3  1 
ATOM   1611 H HE1  . MET A 1 107 ? 10.82384  -15.53528 14.50149  1.000 16.97452  ? 121 MET A HE1  1 
ATOM   1612 H HE2  . MET A 1 107 ? 10.26180  -14.46076 13.47532  0.651 16.97452  ? 121 MET A HE2  1 
ATOM   1613 H HE3  . MET A 1 107 ? 11.10466  -13.98953 14.73668  1.000 16.97452  ? 121 MET A HE3  1 
ATOM   1614 N N    . GLN A 1 108 ? 7.61334   -10.80183 11.11530  1.000 10.11650  ? 122 GLN A N    1 
ATOM   1615 C CA   . GLN A 1 108 ? 7.04580   -10.70757 9.77658   1.000 11.11214  ? 122 GLN A CA   1 
ATOM   1616 C C    . GLN A 1 108 ? 7.94786   -11.36560 8.75461   1.000 10.59458  ? 122 GLN A C    1 
ATOM   1617 O O    . GLN A 1 108 ? 9.16163   -11.49204 8.93058   1.000 11.38733  ? 122 GLN A O    1 
ATOM   1618 C CB   . GLN A 1 108 ? 6.89697   -9.25900  9.30771   1.000 12.18002  ? 122 GLN A CB   1 
ATOM   1619 C CG   . GLN A 1 108 ? 6.22941   -8.33282  10.27361  1.000 12.91559  ? 122 GLN A CG   1 
ATOM   1620 C CD   . GLN A 1 108 ? 5.76938   -7.07314  9.59932   1.000 14.69586  ? 122 GLN A CD   1 
ATOM   1621 O OE1  . GLN A 1 108 ? 4.99913   -7.13212  8.63840   1.000 16.99460  ? 122 GLN A OE1  1 
ATOM   1622 N NE2  . GLN A 1 108 ? 6.20869   -5.92972  10.08651  1.000 14.99444  ? 122 GLN A NE2  1 
ATOM   1623 H H    . GLN A 1 108 ? 8.47165   -10.75685 11.14498  1.000 12.13469  ? 122 GLN A H    1 
ATOM   1624 H HA   . GLN A 1 108 ? 6.19035   -11.16255 9.82250   1.000 13.32945  ? 122 GLN A HA   1 
ATOM   1625 H HB2  . GLN A 1 108 ? 7.78208   -8.90321  9.13193   0.942 14.61092  ? 122 GLN A HB2  1 
ATOM   1626 H HB3  . GLN A 1 108 ? 6.37004   -9.25498  8.49333   1.000 14.61092  ? 122 GLN A HB3  1 
ATOM   1627 H HG2  . GLN A 1 108 ? 5.45548   -8.77340  10.65808  1.000 15.49360  ? 122 GLN A HG2  1 
ATOM   1628 H HG3  . GLN A 1 108 ? 6.85641   -8.09283  10.97373  1.000 15.49360  ? 122 GLN A HG3  1 
ATOM   1629 H HE21 . GLN A 1 108 ? 6.73752   -5.92612  10.76468  1.000 17.98822  ? 122 GLN A HE21 1 
ATOM   1630 H HE22 . GLN A 1 108 ? 5.96645   -5.18738  9.72617   0.882 17.98822  ? 122 GLN A HE22 1 
ATOM   1631 N N    . ILE A 1 109 ? 7.31162   -11.74081 7.64840   1.000 11.15143  ? 123 ILE A N    1 
ATOM   1632 C CA   . ILE A 1 109 ? 7.95901   -11.80691 6.34538   1.000 11.82806  ? 123 ILE A CA   1 
ATOM   1633 C C    . ILE A 1 109 ? 7.32924   -10.70271 5.52068   1.000 12.51624  ? 123 ILE A C    1 
ATOM   1634 O O    . ILE A 1 109 ? 6.11440   -10.70496 5.31067   1.000 12.54088  ? 123 ILE A O    1 
ATOM   1635 C CB   . ILE A 1 109 ? 7.76398   -13.15713 5.63631   1.000 12.24813  ? 123 ILE A CB   1 
ATOM   1636 C CG1  . ILE A 1 109 ? 8.28733   -14.31074 6.48342   1.000 13.03783  ? 123 ILE A CG1  1 
ATOM   1637 C CG2  . ILE A 1 109 ? 8.42249   -13.12406 4.26933   1.000 13.14201  ? 123 ILE A CG2  1 
ATOM   1638 C CD1  . ILE A 1 109 ? 7.78592   -15.66382 5.99593   1.000 14.38230  ? 123 ILE A CD1  1 
ATOM   1639 H H    . ILE A 1 109 ? 6.48226   -11.96750 7.62931   0.322 13.37661  ? 123 ILE A H    1 
ATOM   1640 H HA   . ILE A 1 109 ? 8.91314   -11.67073 6.45491   1.000 14.18857  ? 123 ILE A HA   1 
ATOM   1641 H HB   . ILE A 1 109 ? 6.81291   -13.30527 5.51626   0.681 14.69265  ? 123 ILE A HB   1 
ATOM   1642 H HG12 . ILE A 1 109 ? 9.25660   -14.31698 6.44638   1.000 15.64029  ? 123 ILE A HG12 1 
ATOM   1643 H HG13 . ILE A 1 109 ? 7.99108   -14.19134 7.39932   0.568 15.64029  ? 123 ILE A HG13 1 
ATOM   1644 H HG21 . ILE A 1 109 ? 9.35447   -12.87622 4.37367   1.000 15.76530  ? 123 ILE A HG21 1 
ATOM   1645 H HG22 . ILE A 1 109 ? 8.35733   -14.00383 3.86604   0.163 15.76530  ? 123 ILE A HG22 1 
ATOM   1646 H HG23 . ILE A 1 109 ? 7.96674   -12.47148 3.71496   1.000 15.76530  ? 123 ILE A HG23 1 
ATOM   1647 H HD11 . ILE A 1 109 ? 8.13121   -15.82595 5.10409   1.000 17.25365  ? 123 ILE A HD11 1 
ATOM   1648 H HD12 . ILE A 1 109 ? 8.09852   -16.35354 6.60211   1.000 17.25365  ? 123 ILE A HD12 1 
ATOM   1649 H HD13 . ILE A 1 109 ? 6.81613   -15.65360 5.97837   1.000 17.25365  ? 123 ILE A HD13 1 
ATOM   1650 N N    . ASN A 1 110 ? 8.13106   -9.74804  5.08330   1.000 13.02460  ? 124 ASN A N    1 
ATOM   1651 C CA   A ASN A 1 110 ? 7.65925   -8.66406  4.23701   0.581 13.43216  ? 124 ASN A CA   1 
ATOM   1652 C CA   B ASN A 1 110 ? 7.66957   -8.65743  4.23834   0.419 13.46568  ? 124 ASN A CA   1 
ATOM   1653 C C    . ASN A 1 110 ? 8.44096   -8.68215  2.93168   1.000 13.96659  ? 124 ASN A C    1 
ATOM   1654 O O    . ASN A 1 110 ? 9.42351   -9.39650  2.78110   1.000 13.60787  ? 124 ASN A O    1 
ATOM   1655 C CB   A ASN A 1 110 ? 7.79824   -7.31548  4.95809   0.581 14.71165  ? 124 ASN A CB   1 
ATOM   1656 C CB   B ASN A 1 110 ? 7.91708   -7.29580  4.90400   0.419 14.18805  ? 124 ASN A CB   1 
ATOM   1657 C CG   A ASN A 1 110 ? 6.85404   -6.25778  4.42266   0.581 16.71604  ? 124 ASN A CG   1 
ATOM   1658 C CG   B ASN A 1 110 ? 6.81824   -6.88310  5.85579   0.419 14.85182  ? 124 ASN A CG   1 
ATOM   1659 O OD1  A ASN A 1 110 ? 5.88895   -6.55831  3.73665   0.581 16.88284  ? 124 ASN A OD1  1 
ATOM   1660 O OD1  B ASN A 1 110 ? 6.73483   -5.71669  6.23844   0.419 16.10466  ? 124 ASN A OD1  1 
ATOM   1661 N ND2  A ASN A 1 110 ? 7.12415   -5.01105  4.75328   0.581 19.01264  ? 124 ASN A ND2  1 
ATOM   1662 N ND2  B ASN A 1 110 ? 5.97380   -7.82767  6.24993   0.419 13.90863  ? 124 ASN A ND2  1 
ATOM   1663 H H    . ASN A 1 110 ? 8.96994   -9.70746  5.26830   0.807 15.62441  ? 124 ASN A H    1 
ATOM   1664 H HA   . ASN A 1 110 ? 6.72057   -8.78256  4.02313   1.000 16.15371  ? 124 ASN A HA   1 
ATOM   1665 N N    . SER A 1 111 ? 7.98004   -7.88465  1.98326   1.000 14.95077  ? 125 SER A N    1 
ATOM   1666 C CA   . SER A 1 111 ? 8.64731   -7.76564  0.69862   1.000 15.63143  ? 125 SER A CA   1 
ATOM   1667 C C    . SER A 1 111 ? 8.41098   -6.35660  0.18305   1.000 17.15223  ? 125 SER A C    1 
ATOM   1668 O O    . SER A 1 111 ? 7.77399   -5.53144  0.84103   1.000 18.65538  ? 125 SER A O    1 
ATOM   1669 C CB   . SER A 1 111 ? 8.11078   -8.80112  -0.29130  1.000 16.69026  ? 125 SER A CB   1 
ATOM   1670 O OG   . SER A 1 111 ? 6.76858   -8.51176  -0.61693  1.000 17.73922  ? 125 SER A OG   1 
ATOM   1671 H H    . SER A 1 111 ? 7.27570   -7.39717  2.05983   0.887 17.93581  ? 125 SER A H    1 
ATOM   1672 H HA   . SER A 1 111 ? 9.59932   -7.91051  0.81517   1.000 18.75261  ? 125 SER A HA   1 
ATOM   1673 H HB2  . SER A 1 111 ? 8.64694   -8.77715  -1.09930  0.517 20.02321  ? 125 SER A HB2  1 
ATOM   1674 H HB3  . SER A 1 111 ? 8.15797   -9.68196  0.11216   1.000 20.02321  ? 125 SER A HB3  1 
ATOM   1675 H HG   . SER A 1 111 ? 6.56773   -8.86802  -1.35064  1.000 21.28196  ? 125 SER A HG   1 
ATOM   1676 N N    . GLY A 1 112 ? 8.91393   -6.09120  -1.01741  1.000 19.00308  ? 126 GLY A N    1 
ATOM   1677 C CA   . GLY A 1 112 ? 8.68021   -4.80141  -1.63244  1.000 22.31758  ? 126 GLY A CA   1 
ATOM   1678 C C    . GLY A 1 112 ? 7.24120   -4.54778  -2.01926  1.000 26.78515  ? 126 GLY A C    1 
ATOM   1679 O O    . GLY A 1 112 ? 6.90214   -3.40484  -2.34868  1.000 30.92868  ? 126 GLY A O    1 
ATOM   1680 H H    . GLY A 1 112 ? 9.38637   -6.63611  -1.48589  1.000 22.79859  ? 126 GLY A H    1 
ATOM   1681 H HA2  . GLY A 1 112 ? 8.94913   -4.10574  -1.01225  1.000 26.77599  ? 126 GLY A HA2  1 
ATOM   1682 H HA3  . GLY A 1 112 ? 9.22071   -4.73503  -2.43516  0.102 26.77599  ? 126 GLY A HA3  1 
ATOM   1683 N N    . GLU A 1 113 ? 6.39996   -5.57973  -2.03055  1.000 27.47295  ? 127 GLU A N    1 
ATOM   1684 C CA   . GLU A 1 113 ? 5.00752   -5.43380  -2.44312  1.000 31.33477  ? 127 GLU A CA   1 
ATOM   1685 C C    . GLU A 1 113 ? 4.03542   -5.44605  -1.26910  1.000 27.97611  ? 127 GLU A C    1 
ATOM   1686 O O    . GLU A 1 113 ? 3.16549   -4.57594  -1.16813  1.000 28.80782  ? 127 GLU A O    1 
ATOM   1687 C CB   . GLU A 1 113 ? 4.62343   -6.53502  -3.44464  1.000 38.14145  ? 127 GLU A CB   1 
ATOM   1688 C CG   . GLU A 1 113 ? 4.51444   -6.05743  -4.90638  1.000 43.80744  ? 127 GLU A CG   1 
ATOM   1689 C CD   . GLU A 1 113 ? 3.30678   -5.14187  -5.18036  1.000 47.68004  ? 127 GLU A CD   1 
ATOM   1690 O OE1  . GLU A 1 113 ? 2.17699   -5.47691  -4.74584  1.000 49.23915  ? 127 GLU A OE1  1 
ATOM   1691 O OE2  . GLU A 1 113 ? 3.49354   -4.08983  -5.84206  1.000 48.95385  ? 127 GLU A OE2  1 
ATOM   1692 H H    . GLU A 1 113 ? 6.61493   -6.38032  -1.80155  1.000 32.96243  ? 127 GLU A H    1 
ATOM   1693 H HA   . GLU A 1 113 ? 4.91821   -4.57886  -2.89258  0.319 37.59662  ? 127 GLU A HA   1 
ATOM   1694 H HB2  . GLU A 1 113 ? 5.29846   -7.23088  -3.41300  1.000 45.76463  ? 127 GLU A HB2  1 
ATOM   1695 H HB3  . GLU A 1 113 ? 3.76076   -6.89780  -3.18952  1.000 45.76463  ? 127 GLU A HB3  1 
ATOM   1696 H HG2  . GLU A 1 113 ? 5.31689   -5.56141  -5.13207  1.000 52.56381  ? 127 GLU A HG2  1 
ATOM   1697 H HG3  . GLU A 1 113 ? 4.43152   -6.83389  -5.48182  1.000 52.56381  ? 127 GLU A HG3  1 
ATOM   1698 N N    . ALA A 1 114 ? 4.15702   -6.41365  -0.37518  1.000 25.12992  ? 128 ALA A N    1 
ATOM   1699 C CA   . ALA A 1 114 ? 3.16751   -6.60713  0.67126   1.000 21.60256  ? 128 ALA A CA   1 
ATOM   1700 C C    . ALA A 1 114 ? 3.71809   -7.61271  1.66238   1.000 19.94150  ? 128 ALA A C    1 
ATOM   1701 O O    . ALA A 1 114 ? 4.67675   -8.33229  1.35165   1.000 21.10283  ? 128 ALA A O    1 
ATOM   1702 C CB   . ALA A 1 114 ? 1.84650   -7.13181  0.09195   1.000 22.24441  ? 128 ALA A CB   1 
ATOM   1703 H H    . ALA A 1 114 ? 4.80829   -6.97488  -0.35370  1.000 30.15079  ? 128 ALA A H    1 
ATOM   1704 H HA   . ALA A 1 114 ? 3.00641   -5.76658  1.12779   0.519 25.91797  ? 128 ALA A HA   1 
ATOM   1705 H HB1  . ALA A 1 114 ? 2.03361   -7.88659  -0.48787  1.000 26.68818  ? 128 ALA A HB1  1 
ATOM   1706 H HB2  . ALA A 1 114 ? 1.27020   -7.40967  0.82104   1.000 26.68818  ? 128 ALA A HB2  1 
ATOM   1707 H HB3  . ALA A 1 114 ? 1.42030   -6.42302  -0.41487  0.046 26.68818  ? 128 ALA A HB3  1 
ATOM   1708 N N    . PRO A 1 115 ? 3.11619   -7.69465  2.85008   1.000 17.38821  ? 129 PRO A N    1 
ATOM   1709 C CA   . PRO A 1 115 ? 3.58793   -8.66012  3.84782   1.000 16.13428  ? 129 PRO A CA   1 
ATOM   1710 C C    . PRO A 1 115 ? 3.06445   -10.05955 3.56671   1.000 14.45679  ? 129 PRO A C    1 
ATOM   1711 O O    . PRO A 1 115 ? 1.85626   -10.31152 3.60256   1.000 14.84828  ? 129 PRO A O    1 
ATOM   1712 C CB   . PRO A 1 115 ? 3.02442   -8.11072  5.16213   1.000 17.76556  ? 129 PRO A CB   1 
ATOM   1713 C CG   . PRO A 1 115 ? 1.79712   -7.36996  4.75668   1.000 19.46918  ? 129 PRO A CG   1 
ATOM   1714 C CD   . PRO A 1 115 ? 2.12275   -6.76051  3.41563   1.000 18.90906  ? 129 PRO A CD   1 
ATOM   1715 H HA   . PRO A 1 115 ? 4.55760   -8.67561  3.86789   1.000 19.35602  ? 129 PRO A HA   1 
ATOM   1716 H HB2  . PRO A 1 115 ? 2.80928   -8.84112  5.76307   0.279 21.31356  ? 129 PRO A HB2  1 
ATOM   1717 H HB3  . PRO A 1 115 ? 3.66915   -7.51751  5.57845   1.000 21.31356  ? 129 PRO A HB3  1 
ATOM   1718 H HG2  . PRO A 1 115 ? 1.05037   -7.98481  4.68440   0.311 23.35790  ? 129 PRO A HG2  1 
ATOM   1719 H HG3  . PRO A 1 115 ? 1.59763   -6.68107  5.40978   1.000 23.35790  ? 129 PRO A HG3  1 
ATOM   1720 H HD2  . PRO A 1 115 ? 1.33217   -6.71656  2.85533   1.000 22.68577  ? 129 PRO A HD2  1 
ATOM   1721 H HD3  . PRO A 1 115 ? 2.50344   -5.87474  3.52231   1.000 22.68577  ? 129 PRO A HD3  1 
ATOM   1722 N N    . GLN A 1 116 ? 3.98971   -10.97917 3.31267   1.000 13.34657  ? 130 GLN A N    1 
ATOM   1723 C CA   . GLN A 1 116 ? 3.62077   -12.37808 3.17637   1.000 13.07492  ? 130 GLN A CA   1 
ATOM   1724 C C    . GLN A 1 116 ? 3.07048   -12.92607 4.48209   1.000 12.46406  ? 130 GLN A C    1 
ATOM   1725 O O    . GLN A 1 116 ? 2.11918   -13.71492 4.47662   1.000 12.66135  ? 130 GLN A O    1 
ATOM   1726 C CB   . GLN A 1 116 ? 4.83054   -13.20234 2.76084   1.000 14.03587  ? 130 GLN A CB   1 
ATOM   1727 C CG   . GLN A 1 116 ? 5.28920   -13.01961 1.34187   1.000 15.16586  ? 130 GLN A CG   1 
ATOM   1728 C CD   . GLN A 1 116 ? 5.86903   -11.66211 1.06279   1.000 16.22824  ? 130 GLN A CD   1 
ATOM   1729 O OE1  . GLN A 1 116 ? 6.53626   -11.06185 1.91307   1.000 15.94561  ? 130 GLN A OE1  1 
ATOM   1730 N NE2  . GLN A 1 116 ? 5.65008   -11.17164 -0.15490  1.000 17.90771  ? 130 GLN A NE2  1 
ATOM   1731 H H    . GLN A 1 116 ? 4.82919   -10.81944 3.21595   0.232 16.01078  ? 130 GLN A H    1 
ATOM   1732 H HA   . GLN A 1 116 ? 2.94077   -12.44896 2.48827   1.000 15.68480  ? 130 GLN A HA   1 
ATOM   1733 H HB2  . GLN A 1 116 ? 5.57374   -12.96282 3.33633   1.000 16.83794  ? 130 GLN A HB2  1 
ATOM   1734 H HB3  . GLN A 1 116 ? 4.61239   -14.14070 2.87391   1.000 16.83794  ? 130 GLN A HB3  1 
ATOM   1735 H HG2  . GLN A 1 116 ? 5.97360   -13.67899 1.14766   1.000 18.19393  ? 130 GLN A HG2  1 
ATOM   1736 H HG3  . GLN A 1 116 ? 4.53080   -13.14445 0.75013   1.000 18.19393  ? 130 GLN A HG3  1 
ATOM   1737 H HE21 . GLN A 1 116 ? 5.19937   -11.62812 -0.72769  0.776 21.48415  ? 130 GLN A HE21 1 
ATOM   1738 H HE22 . GLN A 1 116 ? 5.95931   -10.39824 -0.36895  1.000 21.48415  ? 130 GLN A HE22 1 
ATOM   1739 N N    . LEU A 1 117 ? 3.66763   -12.52907 5.61358   1.000 11.37936  ? 131 LEU A N    1 
ATOM   1740 C CA   . LEU A 1 117 ? 3.29449   -13.05501 6.91712   1.000 11.15665  ? 131 LEU A CA   1 
ATOM   1741 C C    . LEU A 1 117 ? 3.44240   -11.97117 7.96633   1.000 10.90064  ? 131 LEU A C    1 
ATOM   1742 O O    . LEU A 1 117 ? 4.49042   -11.33083 8.06146   1.000 11.21904  ? 131 LEU A O    1 
ATOM   1743 C CB   . LEU A 1 117 ? 4.20168   -14.22993 7.31010   1.000 11.36539  ? 131 LEU A CB   1 
ATOM   1744 C CG   . LEU A 1 117 ? 4.10196   -14.72533 8.75732   1.000 11.38615  ? 131 LEU A CG   1 
ATOM   1745 C CD1  . LEU A 1 117 ? 2.73538   -15.31611 9.05542   1.000 11.55572  ? 131 LEU A CD1  1 
ATOM   1746 C CD2  . LEU A 1 117 ? 5.18564   -15.73566 9.04607   1.000 12.12120  ? 131 LEU A CD2  1 
ATOM   1747 H H    . LEU A 1 117 ? 4.30016   -11.94726 5.64514   1.000 13.65013  ? 131 LEU A H    1 
ATOM   1748 H HA   . LEU A 1 117 ? 2.36831   -13.34102 6.88141   0.868 13.38287  ? 131 LEU A HA   1 
ATOM   1749 H HB2  . LEU A 1 117 ? 3.98319   -14.98150 6.73712   1.000 13.63336  ? 131 LEU A HB2  1 
ATOM   1750 H HB3  . LEU A 1 117 ? 5.12180   -13.95905 7.16556   1.000 13.63336  ? 131 LEU A HB3  1 
ATOM   1751 H HG   . LEU A 1 117 ? 4.22303   -13.96403 9.34612   1.000 13.65827  ? 131 LEU A HG   1 
ATOM   1752 H HD11 . LEU A 1 117 ? 2.05277   -14.67070 8.81376   1.000 13.86175  ? 131 LEU A HD11 1 
ATOM   1753 H HD12 . LEU A 1 117 ? 2.62202   -16.12754 8.53616   1.000 13.86175  ? 131 LEU A HD12 1 
ATOM   1754 H HD13 . LEU A 1 117 ? 2.67864   -15.51871 10.00232  1.000 13.86175  ? 131 LEU A HD13 1 
ATOM   1755 H HD21 . LEU A 1 117 ? 6.05069   -15.31909 8.90797   1.000 14.54033  ? 131 LEU A HD21 1 
ATOM   1756 H HD22 . LEU A 1 117 ? 5.10424   -16.03183 9.96615   1.000 14.54033  ? 131 LEU A HD22 1 
ATOM   1757 H HD23 . LEU A 1 117 ? 5.08216   -16.49017 8.44532   1.000 14.54033  ? 131 LEU A HD23 1 
ATOM   1758 N N    . ARG A 1 118 ? 2.44421   -11.85138 8.83033   1.000 10.52800  ? 132 ARG A N    1 
ATOM   1759 C CA   . ARG A 1 118 ? 2.58316   -11.14825 10.09671  1.000 10.81056  ? 132 ARG A CA   1 
ATOM   1760 C C    . ARG A 1 118 ? 2.17439   -12.07682 11.21801  1.000 10.20517  ? 132 ARG A C    1 
ATOM   1761 O O    . ARG A 1 118 ? 1.09763   -12.67386 11.16489  1.000 11.38566  ? 132 ARG A O    1 
ATOM   1762 C CB   . ARG A 1 118 ? 1.70904   -9.89751  10.16692  1.000 11.56632  ? 132 ARG A CB   1 
ATOM   1763 C CG   . ARG A 1 118 ? 2.04934   -8.85850  9.13119   1.000 12.94709  ? 132 ARG A CG   1 
ATOM   1764 C CD   . ARG A 1 118 ? 1.31731   -7.54547  9.36178   1.000 15.00163  ? 132 ARG A CD   1 
ATOM   1765 N NE   . ARG A 1 118 ? -0.12622  -7.71212  9.25302   1.000 15.97746  ? 132 ARG A NE   1 
ATOM   1766 C CZ   . ARG A 1 118 ? -0.96597  -7.82367  10.27169  1.000 17.96712  ? 132 ARG A CZ   1 
ATOM   1767 N NH1  . ARG A 1 118 ? -0.57398  -7.65607  11.52424  1.000 17.75069  ? 132 ARG A NH1  1 
ATOM   1768 N NH2  . ARG A 1 118 ? -2.24489  -8.08894  10.02154  1.000 20.20658  ? 132 ARG A NH2  1 
ATOM   1769 H H    . ARG A 1 118 ? 1.65847   -12.17663 8.70221   1.000 12.62850  ? 132 ARG A H    1 
ATOM   1770 H HA   . ARG A 1 118 ? 3.51141   -10.88573 10.19833  1.000 12.96756  ? 132 ARG A HA   1 
ATOM   1771 H HB2  . ARG A 1 118 ? 0.78375   -10.15624 10.03354  1.000 13.87447  ? 132 ARG A HB2  1 
ATOM   1772 H HB3  . ARG A 1 118 ? 1.81709   -9.49060  11.04079  1.000 13.87447  ? 132 ARG A HB3  1 
ATOM   1773 H HG2  . ARG A 1 118 ? 3.00242   -8.68063  9.16109   1.000 15.53140  ? 132 ARG A HG2  1 
ATOM   1774 H HG3  . ARG A 1 118 ? 1.80126   -9.19106  8.25440   1.000 15.53140  ? 132 ARG A HG3  1 
ATOM   1775 H HD2  . ARG A 1 118 ? 1.52021   -7.21676  10.25154  1.000 17.99685  ? 132 ARG A HD2  1 
ATOM   1776 H HD3  . ARG A 1 118 ? 1.60066   -6.89883  8.69659   0.625 17.99685  ? 132 ARG A HD3  1 
ATOM   1777 H HE   . ARG A 1 118 ? -0.46108  -7.74042  8.46140   1.000 19.16784  ? 132 ARG A HE   1 
ATOM   1778 H HH11 . ARG A 1 118 ? 0.24756   -7.46880  11.69630  1.000 21.29572  ? 132 ARG A HH11 1 
ATOM   1779 H HH12 . ARG A 1 118 ? -1.14073  -7.73439  12.16631  0.137 21.29572  ? 132 ARG A HH12 1 
ATOM   1780 H HH21 . ARG A 1 118 ? -2.51345  -8.18481  9.21019   1.000 24.24279  ? 132 ARG A HH21 1 
ATOM   1781 H HH22 . ARG A 1 118 ? -2.80338  -8.16460  10.67113  1.000 24.24279  ? 132 ARG A HH22 1 
ATOM   1782 N N    . ILE A 1 119 ? 3.02277   -12.19259 12.23434  1.000 10.13123  ? 133 ILE A N    1 
ATOM   1783 C CA   . ILE A 1 119 ? 2.64048   -12.78851 13.50897  1.000 9.92475   ? 133 ILE A CA   1 
ATOM   1784 C C    . ILE A 1 119 ? 2.37735   -11.62135 14.43151  1.000 9.92121   ? 133 ILE A C    1 
ATOM   1785 O O    . ILE A 1 119 ? 3.24187   -10.74889 14.58319  1.000 10.12765  ? 133 ILE A O    1 
ATOM   1786 C CB   . ILE A 1 119 ? 3.73349   -13.71706 14.06019  1.000 10.04701  ? 133 ILE A CB   1 
ATOM   1787 C CG1  . ILE A 1 119 ? 3.97413   -14.87675 13.08145  1.000 11.23264  ? 133 ILE A CG1  1 
ATOM   1788 C CG2  . ILE A 1 119 ? 3.34936   -14.21099 15.44799  1.000 11.30386  ? 133 ILE A CG2  1 
ATOM   1789 C CD1  . ILE A 1 119 ? 4.97184   -15.89206 13.57813  1.000 12.95108  ? 133 ILE A CD1  1 
ATOM   1790 H H    . ILE A 1 119 ? 3.84066   -11.92802 12.20848  1.000 12.15236  ? 133 ILE A H    1 
ATOM   1791 H HA   . ILE A 1 119 ? 1.83922   -13.32731 13.41629  1.000 11.90459  ? 133 ILE A HA   1 
ATOM   1792 H HB   . ILE A 1 119 ? 4.56509   -13.22498 14.14501  1.000 12.05131  ? 133 ILE A HB   1 
ATOM   1793 H HG12 . ILE A 1 119 ? 3.13370   -15.33678 12.93000  1.000 13.47406  ? 133 ILE A HG12 1 
ATOM   1794 H HG13 . ILE A 1 119 ? 4.30986   -14.51556 12.24614  0.406 13.47406  ? 133 ILE A HG13 1 
ATOM   1795 H HG21 . ILE A 1 119 ? 3.26190   -13.44875 16.04149  1.000 13.55952  ? 133 ILE A HG21 1 
ATOM   1796 H HG22 . ILE A 1 119 ? 2.50500   -14.68515 15.39194  1.000 13.55952  ? 133 ILE A HG22 1 
ATOM   1797 H HG23 . ILE A 1 119 ? 4.04210   -14.80646 15.77422  1.000 13.55952  ? 133 ILE A HG23 1 
ATOM   1798 H HD11 . ILE A 1 119 ? 4.57262   -16.39899 14.30239  1.000 15.53619  ? 133 ILE A HD11 1 
ATOM   1799 H HD12 . ILE A 1 119 ? 5.20715   -16.48659 12.84871  0.463 15.53619  ? 133 ILE A HD12 1 
ATOM   1800 H HD13 . ILE A 1 119 ? 5.76270   -15.42863 13.89542  0.496 15.53619  ? 133 ILE A HD13 1 
ATOM   1801 N N    . SER A 1 120 ? 1.18427   -11.57385 15.01802  1.000 10.09846  ? 134 SER A N    1 
ATOM   1802 C CA   . SER A 1 120 ? 0.84658   -10.43905 15.85413  1.000 10.38566  ? 134 SER A CA   1 
ATOM   1803 C C    . SER A 1 120 ? 0.13437   -10.88587 17.11757  1.000 10.96964  ? 134 SER A C    1 
ATOM   1804 O O    . SER A 1 120 ? -0.59077  -11.88281 17.13427  1.000 12.06357  ? 134 SER A O    1 
ATOM   1805 C CB   . SER A 1 120 ? -0.02220  -9.41632  15.10826  1.000 11.51431  ? 134 SER A CB   1 
ATOM   1806 O OG   . SER A 1 120 ? -1.24754  -9.97100  14.70198  1.000 12.77704  ? 134 SER A OG   1 
ATOM   1807 H H    . SER A 1 120 ? 0.57265   -12.17406 14.94546  1.000 12.11305  ? 134 SER A H    1 
ATOM   1808 H HA   . SER A 1 120 ? 1.67320   -10.00993 16.12515  1.000 12.45769  ? 134 SER A HA   1 
ATOM   1809 H HB2  . SER A 1 120 ? -0.19922  -8.66754  15.69893  1.000 13.81206  ? 134 SER A HB2  1 
ATOM   1810 H HB3  . SER A 1 120 ? 0.45861   -9.11256  14.32248  1.000 13.81206  ? 134 SER A HB3  1 
ATOM   1811 H HG   . SER A 1 120 ? -1.68985  -10.21358 15.37363  0.018 15.32734  ? 134 SER A HG   1 
ATOM   1812 N N    . TRP A 1 121 ? 0.33062   -10.10761 18.17150  1.000 10.65836  ? 135 TRP A N    1 
ATOM   1813 C CA   . TRP A 1 121 ? -0.55437  -10.17238 19.31407  1.000 10.91661  ? 135 TRP A CA   1 
ATOM   1814 C C    . TRP A 1 121 ? -1.78727  -9.34842  18.98381  1.000 10.95752  ? 135 TRP A C    1 
ATOM   1815 O O    . TRP A 1 121 ? -1.68559  -8.27597  18.37351  1.000 11.70568  ? 135 TRP A O    1 
ATOM   1816 C CB   . TRP A 1 121 ? 0.11956   -9.59437  20.55842  1.000 11.26193  ? 135 TRP A CB   1 
ATOM   1817 C CG   . TRP A 1 121 ? -0.84456  -9.41686  21.67190  1.000 11.82837  ? 135 TRP A CG   1 
ATOM   1818 C CD1  . TRP A 1 121 ? -1.25320  -10.36023 22.56005  1.000 12.56038  ? 135 TRP A CD1  1 
ATOM   1819 C CD2  . TRP A 1 121 ? -1.60102  -8.23498  21.96574  1.000 12.15428  ? 135 TRP A CD2  1 
ATOM   1820 N NE1  . TRP A 1 121 ? -2.19530  -9.83815  23.40389  1.000 12.86708  ? 135 TRP A NE1  1 
ATOM   1821 C CE2  . TRP A 1 121 ? -2.43015  -8.53415  23.06603  1.000 12.60321  ? 135 TRP A CE2  1 
ATOM   1822 C CE3  . TRP A 1 121 ? -1.66036  -6.95403  21.40328  1.000 13.19435  ? 135 TRP A CE3  1 
ATOM   1823 C CZ2  . TRP A 1 121 ? -3.30010  -7.59075  23.63595  1.000 14.51855  ? 135 TRP A CZ2  1 
ATOM   1824 C CZ3  . TRP A 1 121 ? -2.52933  -6.01887  21.96589  1.000 14.31694  ? 135 TRP A CZ3  1 
ATOM   1825 C CH2  . TRP A 1 121 ? -3.33220  -6.34560  23.06898  1.000 15.06198  ? 135 TRP A CH2  1 
ATOM   1826 H H    . TRP A 1 121 ? 0.96880   -9.53596  18.24596  0.863 12.78493  ? 135 TRP A H    1 
ATOM   1827 H HA   . TRP A 1 121 ? -0.79370  -11.09111 19.51297  0.909 13.09482  ? 135 TRP A HA   1 
ATOM   1828 H HB2  . TRP A 1 121 ? 0.81824   -10.19893 20.85379  0.614 13.50921  ? 135 TRP A HB2  1 
ATOM   1829 H HB3  . TRP A 1 121 ? 0.49943   -8.72817  20.34327  1.000 13.50921  ? 135 TRP A HB3  1 
ATOM   1830 H HD1  . TRP A 1 121 ? -0.93805  -11.23469 22.59013  1.000 15.06735  ? 135 TRP A HD1  1 
ATOM   1831 H HE1  . TRP A 1 121 ? -2.57916  -10.26309 24.04551  1.000 15.43539  ? 135 TRP A HE1  1 
ATOM   1832 H HE3  . TRP A 1 121 ? -1.13216  -6.73161  20.67086  1.000 15.82811  ? 135 TRP A HE3  1 
ATOM   1833 H HZ2  . TRP A 1 121 ? -3.83241  -7.80326  24.36833  0.956 17.41715  ? 135 TRP A HZ2  1 
ATOM   1834 H HZ3  . TRP A 1 121 ? -2.57725  -5.16380  21.60331  1.000 17.17522  ? 135 TRP A HZ3  1 
ATOM   1835 H HH2  . TRP A 1 121 ? -3.90016  -5.70020  23.42364  0.421 18.06927  ? 135 TRP A HH2  1 
ATOM   1836 N N    . ILE A 1 122 ? -2.95668  -9.84257  19.37105  1.000 11.36300  ? 136 ILE A N    1 
ATOM   1837 C CA   . ILE A 1 122 ? -4.18172  -9.10810  19.11596  1.000 13.24246  ? 136 ILE A CA   1 
ATOM   1838 C C    . ILE A 1 122 ? -5.09092  -9.19928  20.33236  1.000 12.04827  ? 136 ILE A C    1 
ATOM   1839 O O    . ILE A 1 122 ? -5.23446  -10.25296 20.96359  1.000 13.02599  ? 136 ILE A O    1 
ATOM   1840 C CB   . ILE A 1 122 ? -4.84020  -9.54706  17.80280  1.000 15.79187  ? 136 ILE A CB   1 
ATOM   1841 C CG1  . ILE A 1 122 ? -6.01496  -8.63404  17.46297  1.000 18.23742  ? 136 ILE A CG1  1 
ATOM   1842 C CG2  . ILE A 1 122 ? -5.24319  -10.95500 17.89591  1.000 17.13286  ? 136 ILE A CG2  1 
ATOM   1843 C CD1  . ILE A 1 122 ? -6.30999  -8.55624  15.97473  1.000 19.46571  ? 136 ILE A CD1  1 
ATOM   1844 H H    . ILE A 1 122 ? -3.06139  -10.59278 19.77826  0.807 13.63049  ? 136 ILE A H    1 
ATOM   1845 H HA   . ILE A 1 122 ? -3.98634  -8.16307  19.01776  1.000 15.88585  ? 136 ILE A HA   1 
ATOM   1846 H HB   . ILE A 1 122 ? -4.19898  -9.46719  17.07936  1.000 18.94514  ? 136 ILE A HB   1 
ATOM   1847 H HG12 . ILE A 1 122 ? -6.81002  -8.96875  17.90655  1.000 21.87980  ? 136 ILE A HG12 1 
ATOM   1848 H HG13 . ILE A 1 122 ? -5.81445  -7.73726  17.77357  1.000 21.87980  ? 136 ILE A HG13 1 
ATOM   1849 H HG21 . ILE A 1 122 ? -5.61661  -11.23353 17.04510  1.000 20.55432  ? 136 ILE A HG21 1 
ATOM   1850 H HG22 . ILE A 1 122 ? -4.46432  -11.49310 18.10734  1.000 20.55432  ? 136 ILE A HG22 1 
ATOM   1851 H HG23 . ILE A 1 122 ? -5.90883  -11.04736 18.59541  1.000 20.55432  ? 136 ILE A HG23 1 
ATOM   1852 H HD11 . ILE A 1 122 ? -5.51380  -8.25408  15.51032  1.000 23.35375  ? 136 ILE A HD11 1 
ATOM   1853 H HD12 . ILE A 1 122 ? -6.56434  -9.43664  15.65675  1.000 23.35375  ? 136 ILE A HD12 1 
ATOM   1854 H HD13 . ILE A 1 122 ? -7.03583  -7.92948  15.82901  1.000 23.35375  ? 136 ILE A HD13 1 
ATOM   1855 N N    . ARG A 1 123 ? -5.69617  -8.06819  20.67068  1.000 12.68708  ? 137 ARG A N    1 
ATOM   1856 C CA   . ARG A 1 123 ? -6.50860  -7.99463  21.87594  1.000 13.71740  ? 137 ARG A CA   1 
ATOM   1857 C C    . ARG A 1 123 ? -7.79420  -8.79533  21.73657  1.000 14.02346  ? 137 ARG A C    1 
ATOM   1858 O O    . ARG A 1 123 ? -8.18011  -9.53005  22.65197  1.000 14.22776  ? 137 ARG A O    1 
ATOM   1859 C CB   . ARG A 1 123 ? -6.83038  -6.53578  22.19200  1.000 16.08897  ? 137 ARG A CB   1 
ATOM   1860 C CG   . ARG A 1 123 ? -7.54214  -6.36923  23.51432  1.000 18.00716  ? 137 ARG A CG   1 
ATOM   1861 C CD   . ARG A 1 123 ? -7.75047  -4.92057  23.88390  1.000 20.42417  ? 137 ARG A CD   1 
ATOM   1862 N NE   . ARG A 1 123 ? -6.48952  -4.24072  24.14575  1.000 21.45578  ? 137 ARG A NE   1 
ATOM   1863 C CZ   . ARG A 1 123 ? -5.82088  -4.29159  25.29164  1.000 22.62125  ? 137 ARG A CZ   1 
ATOM   1864 N NH1  . ARG A 1 123 ? -6.23901  -5.02801  26.31054  1.000 24.01528  ? 137 ARG A NH1  1 
ATOM   1865 N NH2  . ARG A 1 123 ? -4.69763  -3.59190  25.41476  1.000 22.13037  ? 137 ARG A NH2  1 
ATOM   1866 H H    . ARG A 1 123 ? -5.65336  -7.33468  20.22377  1.000 15.21939  ? 137 ARG A H    1 
ATOM   1867 H HA   . ARG A 1 123 ? -6.00088  -8.36991  22.61234  1.000 16.45577  ? 137 ARG A HA   1 
ATOM   1868 H HB2  . ARG A 1 123 ? -6.00302  -6.03089  22.23018  1.000 19.30165  ? 137 ARG A HB2  1 
ATOM   1869 H HB3  . ARG A 1 123 ? -7.40390  -6.18061  21.49499  1.000 19.30165  ? 137 ARG A HB3  1 
ATOM   1870 H HG2  . ARG A 1 123 ? -8.41283  -6.79348  23.46122  1.000 21.60348  ? 137 ARG A HG2  1 
ATOM   1871 H HG3  . ARG A 1 123 ? -7.01304  -6.78409  24.21349  1.000 21.60348  ? 137 ARG A HG3  1 
ATOM   1872 H HD2  . ARG A 1 123 ? -8.19480  -4.46466  23.15203  1.000 24.50389  ? 137 ARG A HD2  1 
ATOM   1873 H HD3  . ARG A 1 123 ? -8.29458  -4.87017  24.68533  0.571 24.50389  ? 137 ARG A HD3  1 
ATOM   1874 H HE   . ARG A 1 123 ? -6.15226  -3.77042  23.50962  1.000 25.74183  ? 137 ARG A HE   1 
ATOM   1875 H HH11 . ARG A 1 123 ? -6.96119  -5.48956  26.23970  1.000 28.81322  ? 137 ARG A HH11 1 
ATOM   1876 H HH12 . ARG A 1 123 ? -5.78825  -5.04447  27.04275  0.417 28.81322  ? 137 ARG A HH12 1 
ATOM   1877 H HH21 . ARG A 1 123 ? -4.41377  -3.11519  24.75767  1.000 26.55133  ? 137 ARG A HH21 1 
ATOM   1878 H HH22 . ARG A 1 123 ? -4.25468  -3.61586  26.15152  1.000 26.55133  ? 137 ARG A HH22 1 
ATOM   1879 N N    A SER A 1 124 ? -8.45140  -8.70834  20.58414  0.537 14.69796  ? 138 SER A N    1 
ATOM   1880 N N    B SER A 1 124 ? -8.51054  -8.60805  20.63143  0.463 14.80430  ? 138 SER A N    1 
ATOM   1881 C CA   A SER A 1 124 ? -9.77481  -9.29455  20.44206  0.537 17.38365  ? 138 SER A CA   1 
ATOM   1882 C CA   B SER A 1 124 ? -9.78675  -9.27022  20.41131  0.463 17.52446  ? 138 SER A CA   1 
ATOM   1883 C C    A SER A 1 124 ? -10.10415 -9.40528  18.96261  0.537 17.19925  ? 138 SER A C    1 
ATOM   1884 C C    B SER A 1 124 ? -9.97028  -9.44406  18.91385  0.463 17.54957  ? 138 SER A C    1 
ATOM   1885 O O    A SER A 1 124 ? -10.04870 -8.40076  18.24903  0.537 18.08470  ? 138 SER A O    1 
ATOM   1886 O O    B SER A 1 124 ? -9.64781  -8.54291  18.13561  0.463 18.70680  ? 138 SER A O    1 
ATOM   1887 C CB   A SER A 1 124 ? -10.78448 -8.37839  21.13699  0.537 20.07601  ? 138 SER A CB   1 
ATOM   1888 C CB   B SER A 1 124 ? -10.96081 -8.44019  20.95710  0.463 19.89564  ? 138 SER A CB   1 
ATOM   1889 O OG   A SER A 1 124 ? -12.09806 -8.85558  20.98894  0.537 21.76777  ? 138 SER A OG   1 
ATOM   1890 O OG   B SER A 1 124 ? -10.78507 -8.08630  22.32278  0.463 21.02144  ? 138 SER A OG   1 
ATOM   1891 H H    A SER A 1 124 ? -8.15346  -8.31837  19.87791  0.537 17.63245  ? 138 SER A H    1 
ATOM   1892 H H    B SER A 1 124 ? -8.27267  -8.09315  19.98498  0.463 17.76005  ? 138 SER A H    1 
ATOM   1893 H HA   A SER A 1 124 ? -9.80681  -10.18639 20.82220  0.537 20.85528  ? 138 SER A HA   1 
ATOM   1894 H HA   B SER A 1 124 ? -9.78407  -10.13433 20.85201  0.463 21.02425  ? 138 SER A HA   1 
ATOM   1895 H HB2  A SER A 1 124 ? -10.57093 -8.33664  22.08227  0.537 24.08611  ? 138 SER A HB2  1 
ATOM   1896 H HB2  B SER A 1 124 ? -11.03470 -7.62692  20.43362  0.463 23.86966  ? 138 SER A HB2  1 
ATOM   1897 H HB3  A SER A 1 124 ? -10.72651 -7.49329  20.74437  0.537 24.08611  ? 138 SER A HB3  1 
ATOM   1898 H HB3  B SER A 1 124 ? -11.77392 -8.96269  20.87488  0.463 23.86966  ? 138 SER A HB3  1 
ATOM   1899 H HG   A SER A 1 124 ? -12.64136 -8.31067  21.32581  0.537 26.11621  ? 138 SER A HG   1 
ATOM   1900 H HG   B SER A 1 124 ? -11.44329 -7.63831  22.59047  0.463 25.22062  ? 138 SER A HG   1 
ATOM   1901 N N    . LYS A 1 125 ? -10.46679 -10.60806 18.51172  1.000 17.00976  ? 139 LYS A N    1 
ATOM   1902 C CA   . LYS A 1 125 ? -10.76028 -10.82125 17.10143  1.000 17.05387  ? 139 LYS A CA   1 
ATOM   1903 C C    . LYS A 1 125 ? -11.58476 -12.08271 16.92754  1.000 15.77368  ? 139 LYS A C    1 
ATOM   1904 O O    . LYS A 1 125 ? -11.33597 -13.10048 17.57671  1.000 16.60702  ? 139 LYS A O    1 
ATOM   1905 C CB   . LYS A 1 125 ? -9.45876  -10.94882 16.30311  1.000 19.91902  ? 139 LYS A CB   1 
ATOM   1906 C CG   . LYS A 1 125 ? -9.62233  -11.28454 14.83094  1.000 23.28204  ? 139 LYS A CG   1 
ATOM   1907 C CD   . LYS A 1 125 ? -9.31269  -10.11499 13.94937  1.000 25.64972  ? 139 LYS A CD   1 
ATOM   1908 C CE   . LYS A 1 125 ? -9.49415  -10.47435 12.47804  1.000 27.14633  ? 139 LYS A CE   1 
ATOM   1909 N NZ   . LYS A 1 125 ? -10.86346 -10.99363 12.14751  1.000 28.44621  ? 139 LYS A NZ   1 
ATOM   1910 H H    . LYS A 1 125 ? -10.54855 -11.30981 19.00210  1.000 20.40660  ? 139 LYS A H    1 
ATOM   1911 H HA   . LYS A 1 125 ? -11.28361 -10.07596 16.76741  0.879 20.45954  ? 139 LYS A HA   1 
ATOM   1912 H HB2  . LYS A 1 125 ? -8.98533  -10.10380 16.35522  1.000 23.89771  ? 139 LYS A HB2  1 
ATOM   1913 H HB3  . LYS A 1 125 ? -8.92460  -11.65350 16.70187  1.000 23.89771  ? 139 LYS A HB3  1 
ATOM   1914 H HG2  . LYS A 1 125 ? -9.01737  -12.00649 14.59915  1.000 27.93334  ? 139 LYS A HG2  1 
ATOM   1915 H HG3  . LYS A 1 125 ? -10.53929 -11.55390 14.66504  1.000 27.93334  ? 139 LYS A HG3  1 
ATOM   1916 H HD2  . LYS A 1 125 ? -9.91182  -9.38246  14.16232  0.427 30.77455  ? 139 LYS A HD2  1 
ATOM   1917 H HD3  . LYS A 1 125 ? -8.39227  -9.84151  14.08704  0.043 30.77455  ? 139 LYS A HD3  1 
ATOM   1918 H HE2  . LYS A 1 125 ? -9.34140  -9.68094  11.94134  1.000 32.57048  ? 139 LYS A HE2  1 
ATOM   1919 H HE3  . LYS A 1 125 ? -8.85231  -11.16258 12.24290  0.010 32.57048  ? 139 LYS A HE3  1 
ATOM   1920 H HZ1  . LYS A 1 125 ? -10.99023 -10.97875 11.26671  1.000 34.13034  ? 139 LYS A HZ1  1 
ATOM   1921 H HZ2  . LYS A 1 125 ? -10.94985 -11.83056 12.43766  0.352 34.13034  ? 139 LYS A HZ2  1 
ATOM   1922 H HZ3  . LYS A 1 125 ? -11.48320 -10.48745 12.53712  1.000 34.13034  ? 139 LYS A HZ3  1 
ATOM   1923 N N    . SER A 1 126 ? -12.56333 -11.99884 16.04201  1.000 15.03608  ? 140 SER A N    1 
ATOM   1924 C CA   A SER A 1 126 ? -13.32347 -13.15923 15.61110  0.832 15.48115  ? 140 SER A CA   1 
ATOM   1925 C CA   B SER A 1 126 ? -13.32331 -13.15918 15.61199  0.168 15.30520  ? 140 SER A CA   1 
ATOM   1926 C C    . SER A 1 126 ? -12.66590 -13.76323 14.37870  1.000 15.43351  ? 140 SER A C    1 
ATOM   1927 O O    . SER A 1 126 ? -12.36289 -13.05383 13.41309  1.000 17.28538  ? 140 SER A O    1 
ATOM   1928 C CB   A SER A 1 126 ? -14.76577 -12.76930 15.28534  0.832 16.81105  ? 140 SER A CB   1 
ATOM   1929 C CB   B SER A 1 126 ? -14.76042 -12.75318 15.29617  0.168 15.63959  ? 140 SER A CB   1 
ATOM   1930 O OG   A SER A 1 126 ? -15.51335 -13.90607 14.88281  0.832 18.76229  ? 140 SER A OG   1 
ATOM   1931 O OG   B SER A 1 126 ? -15.38996 -12.25098 16.45877  0.168 15.96909  ? 140 SER A OG   1 
ATOM   1932 H H    . SER A 1 126 ? -12.81082 -11.26473 15.66860  1.000 18.03818  ? 140 SER A H    1 
ATOM   1933 H HA   . SER A 1 126 ? -13.33589 -13.81972 16.32138  0.561 18.36113  ? 140 SER A HA   1 
ATOM   1934 H HB2  A SER A 1 126 ? -15.17579 -12.38461 16.07579  0.832 20.16816  ? 140 SER A HB2  1 
ATOM   1935 H HB2  B SER A 1 126 ? -14.75427 -12.06371 14.61389  0.168 18.76241  ? 140 SER A HB2  1 
ATOM   1936 H HB3  A SER A 1 126 ? -14.76301 -12.12076 14.56403  0.832 20.16816  ? 140 SER A HB3  1 
ATOM   1937 H HB3  B SER A 1 126 ? -15.24857 -13.52918 14.97926  0.168 18.76241  ? 140 SER A HB3  1 
ATOM   1938 H HG   A SER A 1 126 ? -15.48756 -14.49390 15.48231  0.832 22.50963  ? 140 SER A HG   1 
ATOM   1939 H HG   B SER A 1 126 ? -14.90207 -11.67181 16.82227  0.168 19.15779  ? 140 SER A HG   1 
ATOM   1940 N N    . LEU A 1 127 ? -12.43754 -15.07009 14.42313  1.000 15.48179  ? 141 LEU A N    1 
ATOM   1941 C CA   . LEU A 1 127 ? -11.85914 -15.81442 13.31369  1.000 16.74595  ? 141 LEU A CA   1 
ATOM   1942 C C    . LEU A 1 127 ? -12.77680 -16.98043 13.00709  1.000 17.92437  ? 141 LEU A C    1 
ATOM   1943 O O    . LEU A 1 127 ? -13.04898 -17.80686 13.88326  1.000 18.26710  ? 141 LEU A O    1 
ATOM   1944 C CB   . LEU A 1 127 ? -10.47116 -16.34832 13.65542  1.000 18.02540  ? 141 LEU A CB   1 
ATOM   1945 C CG   . LEU A 1 127 ? -9.39679  -15.29798 13.88925  1.000 18.34926  ? 141 LEU A CG   1 
ATOM   1946 C CD1  . LEU A 1 127 ? -8.09557  -15.96146 14.31075  1.000 19.27813  ? 141 LEU A CD1  1 
ATOM   1947 C CD2  . LEU A 1 127 ? -9.20383  -14.47350 12.63666  1.000 19.13957  ? 141 LEU A CD2  1 
ATOM   1948 H H    . LEU A 1 127 ? -12.61489 -15.56167 15.10614  1.000 18.57304  ? 141 LEU A H    1 
ATOM   1949 H HA   . LEU A 1 127 ? -11.78836 -15.23170 12.54147  1.000 20.09003  ? 141 LEU A HA   1 
ATOM   1950 H HB2  . LEU A 1 127 ? -10.54037 -16.87512 14.46695  1.000 21.62537  ? 141 LEU A HB2  1 
ATOM   1951 H HB3  . LEU A 1 127 ? -10.17229 -16.90753 12.92135  1.000 21.62537  ? 141 LEU A HB3  1 
ATOM   1952 H HG   . LEU A 1 127 ? -9.66984  -14.70204 14.60424  1.000 22.01401  ? 141 LEU A HG   1 
ATOM   1953 H HD11 . LEU A 1 127 ? -7.44835  -15.27417 14.53357  0.525 23.12865  ? 141 LEU A HD11 1 
ATOM   1954 H HD12 . LEU A 1 127 ? -8.26295  -16.52161 15.08478  1.000 23.12865  ? 141 LEU A HD12 1 
ATOM   1955 H HD13 . LEU A 1 127 ? -7.76446  -16.50208 13.57659  1.000 23.12865  ? 141 LEU A HD13 1 
ATOM   1956 H HD21 . LEU A 1 127 ? -9.16030  -15.06760 11.87112  0.545 22.96237  ? 141 LEU A HD21 1 
ATOM   1957 H HD22 . LEU A 1 127 ? -9.95291  -13.86475 12.54076  0.601 22.96237  ? 141 LEU A HD22 1 
ATOM   1958 H HD23 . LEU A 1 127 ? -8.37736  -13.97151 12.71320  1.000 22.96237  ? 141 LEU A HD23 1 
ATOM   1959 N N    . ASP A 1 128 ? -13.25618 -17.04054 11.77010  1.000 19.98824  ? 142 ASP A N    1 
ATOM   1960 C CA   . ASP A 1 128 ? -14.15560 -18.10074 11.33264  1.000 23.36853  ? 142 ASP A CA   1 
ATOM   1961 C C    . ASP A 1 128 ? -15.29837 -18.29782 12.32109  1.000 22.13565  ? 142 ASP A C    1 
ATOM   1962 O O    . ASP A 1 128 ? -15.65295 -19.42197 12.67757  1.000 23.65111  ? 142 ASP A O    1 
ATOM   1963 C CB   . ASP A 1 128 ? -13.40226 -19.40448 11.07504  1.000 29.10445  ? 142 ASP A CB   1 
ATOM   1964 C CG   . ASP A 1 128 ? -12.45461 -19.30270 9.88619   1.000 35.37028  ? 142 ASP A CG   1 
ATOM   1965 O OD1  . ASP A 1 128 ? -12.70850 -18.46796 8.98419   1.000 37.16292  ? 142 ASP A OD1  1 
ATOM   1966 O OD2  . ASP A 1 128 ? -11.45205 -20.05043 9.85474   1.000 38.71134  ? 142 ASP A OD2  1 
ATOM   1967 H H    . ASP A 1 128 ? -13.07200 -16.46879 11.15465  1.000 23.98078  ? 142 ASP A H    1 
ATOM   1968 H HA   . ASP A 1 128 ? -14.55215 -17.83018 10.48976  1.000 28.03713  ? 142 ASP A HA   1 
ATOM   1969 H HB2  . ASP A 1 128 ? -12.87819 -19.62866 11.85989  1.000 34.92024  ? 142 ASP A HB2  1 
ATOM   1970 H HB3  . ASP A 1 128 ? -14.04219 -20.10979 10.89086  1.000 34.92024  ? 142 ASP A HB3  1 
ATOM   1971 N N    . GLY A 1 129 ? -15.86835 -17.18682 12.78109  1.000 20.19949  ? 143 GLY A N    1 
ATOM   1972 C CA   . GLY A 1 129 ? -17.06136 -17.23162 13.60088  1.000 20.48400  ? 143 GLY A CA   1 
ATOM   1973 C C    . GLY A 1 129 ? -16.82420 -17.48723 15.06900  1.000 19.78937  ? 143 GLY A C    1 
ATOM   1974 O O    . GLY A 1 129 ? -17.79864 -17.64282 15.81503  1.000 20.95630  ? 143 GLY A O    1 
ATOM   1975 H H    . GLY A 1 129 ? -15.57705 -16.39223 12.62821  1.000 24.23428  ? 143 GLY A H    1 
ATOM   1976 H HA2  . GLY A 1 129 ? -17.52326 -16.38241 13.52099  1.000 24.57569  ? 143 GLY A HA2  1 
ATOM   1977 H HA3  . GLY A 1 129 ? -17.63814 -17.93730 13.26884  0.203 24.57569  ? 143 GLY A HA3  1 
ATOM   1978 N N    . VAL A 1 130 ? -15.56808 -17.53581 15.51074  1.000 18.62434  ? 144 VAL A N    1 
ATOM   1979 C CA   . VAL A 1 130 ? -15.21696 -17.79034 16.90228  1.000 18.61428  ? 144 VAL A CA   1 
ATOM   1980 C C    . VAL A 1 130 ? -14.43404 -16.60026 17.42989  1.000 15.49956  ? 144 VAL A C    1 
ATOM   1981 O O    . VAL A 1 130 ? -13.45908 -16.16797 16.80714  1.000 15.77163  ? 144 VAL A O    1 
ATOM   1982 C CB   . VAL A 1 130 ? -14.38539 -19.07579 17.04167  1.000 22.07990  ? 144 VAL A CB   1 
ATOM   1983 C CG1  . VAL A 1 130 ? -13.99247 -19.29534 18.49898  1.000 23.59592  ? 144 VAL A CG1  1 
ATOM   1984 C CG2  . VAL A 1 130 ? -15.16381 -20.26722 16.49340  1.000 23.99651  ? 144 VAL A CG2  1 
ATOM   1985 H H    . VAL A 1 130 ? -14.88231 -17.42038 15.00478  0.527 22.34410  ? 144 VAL A H    1 
ATOM   1986 H HA   . VAL A 1 130 ? -16.02976 -17.87971 17.42407  1.000 22.33202  ? 144 VAL A HA   1 
ATOM   1987 H HB   . VAL A 1 130 ? -13.56893 -18.99054 16.52492  0.734 26.49077  ? 144 VAL A HB   1 
ATOM   1988 H HG11 . VAL A 1 130 ? -13.36657 -18.60367 18.76495  0.944 28.31000  ? 144 VAL A HG11 1 
ATOM   1989 H HG12 . VAL A 1 130 ? -14.78888 -19.25079 19.05094  0.505 28.31000  ? 144 VAL A HG12 1 
ATOM   1990 H HG13 . VAL A 1 130 ? -13.57791 -20.16793 18.58627  1.000 28.31000  ? 144 VAL A HG13 1 
ATOM   1991 H HG21 . VAL A 1 130 ? -16.10540 -20.03770 16.45301  0.221 28.79070  ? 144 VAL A HG21 1 
ATOM   1992 H HG22 . VAL A 1 130 ? -14.83601 -20.47675 15.60484  1.000 28.79070  ? 144 VAL A HG22 1 
ATOM   1993 H HG23 . VAL A 1 130 ? -15.03358 -21.02732 17.08178  0.466 28.79070  ? 144 VAL A HG23 1 
ATOM   1994 N N    . ALA A 1 131 ? -14.84257 -16.09471 18.58515  1.000 15.18487  ? 145 ALA A N    1 
ATOM   1995 C CA   . ALA A 1 131 ? -14.15695 -14.97604 19.20399  1.000 15.28240  ? 145 ALA A CA   1 
ATOM   1996 C C    . ALA A 1 131 ? -12.96320 -15.48431 19.99303  1.000 14.76117  ? 145 ALA A C    1 
ATOM   1997 O O    . ALA A 1 131 ? -13.09108 -16.42364 20.78422  1.000 17.34968  ? 145 ALA A O    1 
ATOM   1998 C CB   . ALA A 1 131 ? -15.11323 -14.25217 20.14083  1.000 16.21992  ? 145 ALA A CB   1 
ATOM   1999 H H    . ALA A 1 131 ? -15.51807 -16.38465 19.03150  1.000 18.21674  ? 145 ALA A H    1 
ATOM   2000 H HA   . ALA A 1 131 ? -13.84538 -14.35864 18.52381  1.000 18.33377  ? 145 ALA A HA   1 
ATOM   2001 H HB1  . ALA A 1 131 ? -15.87853 -13.94120 19.63239  0.385 19.45879  ? 145 ALA A HB1  1 
ATOM   2002 H HB2  . ALA A 1 131 ? -15.40345 -14.86701 20.83267  1.000 19.45879  ? 145 ALA A HB2  1 
ATOM   2003 H HB3  . ALA A 1 131 ? -14.65302 -13.49768 20.54063  1.000 19.45879  ? 145 ALA A HB3  1 
ATOM   2004 N N    . TYR A 1 132 ? -11.81571 -14.84776 19.78986  1.000 15.18083  ? 146 TYR A N    1 
ATOM   2005 C CA   . TYR A 1 132 ? -10.60604 -15.09732 20.54829  1.000 15.64697  ? 146 TYR A CA   1 
ATOM   2006 C C    . TYR A 1 132 ? -10.15229 -13.78934 21.17307  1.000 15.09484  ? 146 TYR A C    1 
ATOM   2007 O O    . TYR A 1 132 ? -10.35980 -12.70965 20.62116  1.000 15.81538  ? 146 TYR A O    1 
ATOM   2008 C CB   . TYR A 1 132 ? -9.48514  -15.64378 19.64715  1.000 17.47876  ? 146 TYR A CB   1 
ATOM   2009 C CG   . TYR A 1 132 ? -9.83447  -16.95261 18.98843  1.000 18.93379  ? 146 TYR A CG   1 
ATOM   2010 C CD1  . TYR A 1 132 ? -9.65171  -18.15526 19.65003  1.000 21.18416  ? 146 TYR A CD1  1 
ATOM   2011 C CD2  . TYR A 1 132 ? -10.34625 -16.98160 17.69833  1.000 19.70265  ? 146 TYR A CD2  1 
ATOM   2012 C CE1  . TYR A 1 132 ? -9.97873  -19.35020 19.04334  1.000 22.34018  ? 146 TYR A CE1  1 
ATOM   2013 C CE2  . TYR A 1 132 ? -10.67100 -18.15839 17.08945  1.000 21.73687  ? 146 TYR A CE2  1 
ATOM   2014 C CZ   . TYR A 1 132 ? -10.49005 -19.34116 17.76039  1.000 22.70421  ? 146 TYR A CZ   1 
ATOM   2015 O OH   . TYR A 1 132 ? -10.82881 -20.51894 17.14240  1.000 25.25085  ? 146 TYR A OH   1 
ATOM   2016 H H    . TYR A 1 132 ? -11.71268 -14.24013 19.19005  1.000 18.21189  ? 146 TYR A H    1 
ATOM   2017 H HA   . TYR A 1 132 ? -10.77644 -15.74928 21.24601  0.909 18.77125  ? 146 TYR A HA   1 
ATOM   2018 H HB2  . TYR A 1 132 ? -9.30227  -14.99747 18.94734  1.000 20.96940  ? 146 TYR A HB2  1 
ATOM   2019 H HB3  . TYR A 1 132 ? -8.69037  -15.78385 20.18533  1.000 20.96940  ? 146 TYR A HB3  1 
ATOM   2020 H HD1  . TYR A 1 132 ? -9.30469  -18.15739 20.51286  1.000 25.41588  ? 146 TYR A HD1  1 
ATOM   2021 H HD2  . TYR A 1 132 ? -10.47029 -16.18217 17.23961  1.000 23.63807  ? 146 TYR A HD2  1 
ATOM   2022 H HE1  . TYR A 1 132 ? -9.85604  -20.15440 19.49401  1.000 26.80311  ? 146 TYR A HE1  1 
ATOM   2023 H HE2  . TYR A 1 132 ? -11.01303 -18.15878 16.22463  1.000 26.07913  ? 146 TYR A HE2  1 
ATOM   2024 H HH   . TYR A 1 132 ? -10.80494 -21.15077 17.69541  1.000 30.29591  ? 146 TYR A HH   1 
ATOM   2025 N N    . GLU A 1 133 ? -9.49374  -13.89310 22.31285  1.000 16.10924  ? 147 GLU A N    1 
ATOM   2026 C CA   . GLU A 1 133 ? -9.03768  -12.72891 23.05250  1.000 16.87203  ? 147 GLU A CA   1 
ATOM   2027 C C    . GLU A 1 133 ? -7.59419  -12.93938 23.47154  1.000 15.81194  ? 147 GLU A C    1 
ATOM   2028 O O    . GLU A 1 133 ? -7.21200  -14.05273 23.84938  1.000 15.76464  ? 147 GLU A O    1 
ATOM   2029 C CB   . GLU A 1 133 ? -9.86911  -12.54075 24.32614  1.000 20.11781  ? 147 GLU A CB   1 
ATOM   2030 C CG   . GLU A 1 133 ? -11.37185 -12.46671 24.10770  1.000 26.13003  ? 147 GLU A CG   1 
ATOM   2031 C CD   . GLU A 1 133 ? -11.87437 -11.04725 23.95612  1.000 31.58947  ? 147 GLU A CD   1 
ATOM   2032 O OE1  . GLU A 1 133 ? -11.03291 -10.13086 23.81619  1.000 33.73968  ? 147 GLU A OE1  1 
ATOM   2033 O OE2  . GLU A 1 133 ? -13.11231 -10.84669 23.98281  1.000 33.93812  ? 147 GLU A OE2  1 
ATOM   2034 H H    . GLU A 1 133 ? -9.29449  -14.64159 22.68655  0.911 19.32598  ? 147 GLU A H    1 
ATOM   2035 H HA   . GLU A 1 133 ? -9.10525  -11.94111 22.49062  0.701 20.24132  ? 147 GLU A HA   1 
ATOM   2036 H HB2  . GLU A 1 133 ? -9.69787  -13.28999 24.91794  1.000 24.13627  ? 147 GLU A HB2  1 
ATOM   2037 H HB3  . GLU A 1 133 ? -9.59596  -11.71287 24.75147  0.731 24.13627  ? 147 GLU A HB3  1 
ATOM   2038 H HG2  . GLU A 1 133 ? -11.59767 -12.95239 23.29899  1.000 31.35092  ? 147 GLU A HG2  1 
ATOM   2039 H HG3  . GLU A 1 133 ? -11.82165 -12.86394 24.86979  1.000 31.35092  ? 147 GLU A HG3  1 
ATOM   2040 N N    . ASP A 1 134 ? -6.80918  -11.86146 23.43850  1.000 14.59866  ? 148 ASP A N    1 
ATOM   2041 C CA   . ASP A 1 134 ? -5.47622  -11.83086 24.03871  1.000 14.10861  ? 148 ASP A CA   1 
ATOM   2042 C C    . ASP A 1 134 ? -4.62403  -12.99328 23.52789  1.000 13.55058  ? 148 ASP A C    1 
ATOM   2043 O O    . ASP A 1 134 ? -4.18892  -13.86879 24.28145  1.000 14.36217  ? 148 ASP A O    1 
ATOM   2044 C CB   . ASP A 1 134 ? -5.59906  -11.84353 25.57155  1.000 14.91989  ? 148 ASP A CB   1 
ATOM   2045 C CG   . ASP A 1 134 ? -4.27329  -11.59302 26.29212  1.000 15.61221  ? 148 ASP A CG   1 
ATOM   2046 O OD1  . ASP A 1 134 ? -3.39313  -10.93055 25.71375  1.000 15.90320  ? 148 ASP A OD1  1 
ATOM   2047 O OD2  . ASP A 1 134 ? -4.13117  -12.04084 27.45743  1.000 16.83333  ? 148 ASP A OD2  1 
ATOM   2048 H H    . ASP A 1 134 ? -7.03250  -11.11945 23.06548  1.000 17.51328  ? 148 ASP A H    1 
ATOM   2049 H HA   . ASP A 1 134 ? -5.02295  -11.01489 23.77484  1.000 16.92522  ? 148 ASP A HA   1 
ATOM   2050 H HB2  . ASP A 1 134 ? -6.21956  -11.14864 25.84177  0.395 17.89876  ? 148 ASP A HB2  1 
ATOM   2051 H HB3  . ASP A 1 134 ? -5.92991  -12.71114 25.85207  0.630 17.89876  ? 148 ASP A HB3  1 
ATOM   2052 N N    . PHE A 1 135 ? -4.38930  -13.00173 22.21614  1.000 12.52253  ? 149 PHE A N    1 
ATOM   2053 C CA   . PHE A 1 135 ? -3.80491  -14.16745 21.58169  1.000 11.83225  ? 149 PHE A CA   1 
ATOM   2054 C C    . PHE A 1 135 ? -2.81931  -13.75795 20.50820  1.000 11.21638  ? 149 PHE A C    1 
ATOM   2055 O O    . PHE A 1 135 ? -2.72400  -12.59668 20.11640  1.000 11.82902  ? 149 PHE A O    1 
ATOM   2056 C CB   . PHE A 1 135 ? -4.87943  -15.10139 21.02222  1.000 12.30524  ? 149 PHE A CB   1 
ATOM   2057 C CG   . PHE A 1 135 ? -5.58632  -14.59293 19.79009  1.000 13.33244  ? 149 PHE A CG   1 
ATOM   2058 C CD1  . PHE A 1 135 ? -6.60451  -13.65024 19.86705  1.000 14.33372  ? 149 PHE A CD1  1 
ATOM   2059 C CD2  . PHE A 1 135 ? -5.24869  -15.09969 18.54674  1.000 14.02533  ? 149 PHE A CD2  1 
ATOM   2060 C CE1  . PHE A 1 135 ? -7.27264  -13.22579 18.72242  1.000 15.35370  ? 149 PHE A CE1  1 
ATOM   2061 C CE2  . PHE A 1 135 ? -5.91768  -14.68717 17.41613  1.000 14.52928  ? 149 PHE A CE2  1 
ATOM   2062 C CZ   . PHE A 1 135 ? -6.91726  -13.74031 17.49912  1.000 15.01706  ? 149 PHE A CZ   1 
ATOM   2063 H H    . PHE A 1 135 ? -4.56020  -12.34844 21.68360  1.000 15.02193  ? 149 PHE A H    1 
ATOM   2064 H HA   . PHE A 1 135 ? -3.29673  -14.65319 22.25006  1.000 14.19359  ? 149 PHE A HA   1 
ATOM   2065 H HB2  . PHE A 1 135 ? -4.46214  -15.94584 20.79054  1.000 14.76119  ? 149 PHE A HB2  1 
ATOM   2066 H HB3  . PHE A 1 135 ? -5.55223  -15.24063 21.70695  1.000 14.76119  ? 149 PHE A HB3  1 
ATOM   2067 H HD1  . PHE A 1 135 ? -6.84253  -13.29840 20.69437  0.954 17.19535  ? 149 PHE A HD1  1 
ATOM   2068 H HD2  . PHE A 1 135 ? -4.56367  -15.72452 18.47447  0.946 16.82528  ? 149 PHE A HD2  1 
ATOM   2069 H HE1  . PHE A 1 135 ? -7.95557  -12.59765 18.78521  1.000 18.41933  ? 149 PHE A HE1  1 
ATOM   2070 H HE2  . PHE A 1 135 ? -5.69370  -15.05000 16.58964  1.000 17.43002  ? 149 PHE A HE2  1 
ATOM   2071 H HZ   . PHE A 1 135 ? -7.34983  -13.45075 16.72845  1.000 18.01536  ? 149 PHE A HZ   1 
ATOM   2072 N N    . ILE A 1 136 ? -2.09160  -14.75886 20.03213  1.000 10.83341  ? 150 ILE A N    1 
ATOM   2073 C CA   . ILE A 1 136 ? -1.11323  -14.60803 18.96894  1.000 11.07137  ? 150 ILE A CA   1 
ATOM   2074 C C    . ILE A 1 136 ? -1.70858  -15.19703 17.70086  1.000 10.99702  ? 150 ILE A C    1 
ATOM   2075 O O    . ILE A 1 136 ? -2.17093  -16.34465 17.69916  1.000 11.63951  ? 150 ILE A O    1 
ATOM   2076 C CB   . ILE A 1 136 ? 0.21617   -15.29550 19.31936  1.000 11.82676  ? 150 ILE A CB   1 
ATOM   2077 C CG1  . ILE A 1 136 ? 0.66646   -14.96680 20.75801  1.000 13.26566  ? 150 ILE A CG1  1 
ATOM   2078 C CG2  . ILE A 1 136 ? 1.24979   -14.91237 18.27648  1.000 13.02126  ? 150 ILE A CG2  1 
ATOM   2079 C CD1  . ILE A 1 136 ? 0.89072   -13.50451 21.03900  1.000 13.04646  ? 150 ILE A CD1  1 
ATOM   2080 H H    . ILE A 1 136 ? -2.15062  -15.56639 20.32200  1.000 12.99498  ? 150 ILE A H    1 
ATOM   2081 H HA   . ILE A 1 136 ? -0.93666  -13.66526 18.82433  1.000 13.28053  ? 150 ILE A HA   1 
ATOM   2082 H HB   . ILE A 1 136 ? 0.09895   -16.25822 19.30148  1.000 14.18701  ? 150 ILE A HB   1 
ATOM   2083 H HG12 . ILE A 1 136 ? -0.01657  -15.27893 21.37196  1.000 15.91368  ? 150 ILE A HG12 1 
ATOM   2084 H HG13 . ILE A 1 136 ? 1.50276   -15.42705 20.93026  1.000 15.91368  ? 150 ILE A HG13 1 
ATOM   2085 H HG21 . ILE A 1 136 ? 1.32337   -13.94568 18.24503  1.000 15.62041  ? 150 ILE A HG21 1 
ATOM   2086 H HG22 . ILE A 1 136 ? 2.10412   -15.30137 18.52081  1.000 15.62041  ? 150 ILE A HG22 1 
ATOM   2087 H HG23 . ILE A 1 136 ? 0.96718   -15.25088 17.41251  1.000 15.62041  ? 150 ILE A HG23 1 
ATOM   2088 H HD11 . ILE A 1 136 ? 0.04563   -13.03476 20.96119  0.730 15.65065  ? 150 ILE A HD11 1 
ATOM   2089 H HD12 . ILE A 1 136 ? 1.24245   -13.40592 21.93759  1.000 15.65065  ? 150 ILE A HD12 1 
ATOM   2090 H HD13 . ILE A 1 136 ? 1.52516   -13.15286 20.39502  1.000 15.65065  ? 150 ILE A HD13 1 
ATOM   2091 N N    . MET A 1 137 ? -1.65178  -14.41860 16.62638  1.000 10.92352  ? 151 MET A N    1 
ATOM   2092 C CA   . MET A 1 137 ? -2.30942  -14.71834 15.36859  1.000 11.27793  ? 151 MET A CA   1 
ATOM   2093 C C    . MET A 1 137 ? -1.28156  -14.67688 14.25124  1.000 11.18163  ? 151 MET A C    1 
ATOM   2094 O O    . MET A 1 137 ? -0.32031  -13.90593 14.30221  1.000 11.89445  ? 151 MET A O    1 
ATOM   2095 C CB   . MET A 1 137 ? -3.34746  -13.62705 15.06687  1.000 13.05930  ? 151 MET A CB   1 
ATOM   2096 C CG   . MET A 1 137 ? -4.21144  -13.88705 13.86152  1.000 14.73708  ? 151 MET A CG   1 
ATOM   2097 S SD   . MET A 1 137 ? -5.59481  -12.73861 13.74758  1.000 16.18168  ? 151 MET A SD   1 
ATOM   2098 C CE   . MET A 1 137 ? -4.76897  -11.21581 13.30766  1.000 19.44985  ? 151 MET A CE   1 
ATOM   2099 H H    . MET A 1 137 ? -1.21691  -13.67700 16.60382  1.000 13.10312  ? 151 MET A H    1 
ATOM   2100 H HA   . MET A 1 137 ? -2.72705  -15.59282 15.41057  0.931 13.52840  ? 151 MET A HA   1 
ATOM   2101 H HB2  . MET A 1 137 ? -3.93561  -13.54236 15.83355  1.000 15.66605  ? 151 MET A HB2  1 
ATOM   2102 H HB3  . MET A 1 137 ? -2.87900  -12.79149 14.91421  1.000 15.66605  ? 151 MET A HB3  1 
ATOM   2103 H HG2  . MET A 1 137 ? -3.67417  -13.79232 13.05948  0.825 17.67938  ? 151 MET A HG2  1 
ATOM   2104 H HG3  . MET A 1 137 ? -4.57017  -14.78661 13.91621  1.000 17.67938  ? 151 MET A HG3  1 
ATOM   2105 H HE1  . MET A 1 137 ? -5.38882  -10.47764 13.41624  1.000 23.33471  ? 151 MET A HE1  1 
ATOM   2106 H HE2  . MET A 1 137 ? -4.00271  -11.09263 13.88952  1.000 23.33471  ? 151 MET A HE2  1 
ATOM   2107 H HE3  . MET A 1 137 ? -4.47763  -11.26998 12.38403  0.739 23.33471  ? 151 MET A HE3  1 
ATOM   2108 N N    . SER A 1 138 ? -1.45923  -15.52343 13.24567  1.000 10.40938  ? 152 SER A N    1 
ATOM   2109 C CA   . SER A 1 138 ? -0.75396  -15.34879 11.98833  1.000 10.67114  ? 152 SER A CA   1 
ATOM   2110 C C    . SER A 1 138 ? -1.70771  -14.83115 10.92933  1.000 10.12562  ? 152 SER A C    1 
ATOM   2111 O O    . SER A 1 138 ? -2.86493  -15.25579 10.85552  1.000 11.15853  ? 152 SER A O    1 
ATOM   2112 C CB   . SER A 1 138 ? -0.10105  -16.62793 11.48480  1.000 12.06959  ? 152 SER A CB   1 
ATOM   2113 O OG   . SER A 1 138 ? -1.00167  -17.69422 11.32093  1.000 13.24554  ? 152 SER A OG   1 
ATOM   2114 H H    . SER A 1 138 ? -1.98305  -16.20506 13.27015  1.000 12.48615  ? 152 SER A H    1 
ATOM   2115 H HA   . SER A 1 138 ? -0.04651  -14.70150 12.13473  1.000 12.80025  ? 152 SER A HA   1 
ATOM   2116 H HB2  . SER A 1 138 ? 0.31019   -16.44216 10.62615  1.000 14.47839  ? 152 SER A HB2  1 
ATOM   2117 H HB3  . SER A 1 138 ? 0.57573   -16.89685 12.12554  1.000 14.47839  ? 152 SER A HB3  1 
ATOM   2118 H HG   . SER A 1 138 ? -1.39848  -17.84897 12.04495  1.000 15.88954  ? 152 SER A HG   1 
ATOM   2119 N N    . THR A 1 139 ? -1.21002  -13.91368 10.10593  1.000 9.92223   ? 153 THR A N    1 
ATOM   2120 C CA   . THR A 1 139 ? -1.92404  -13.40886 8.93158   1.000 11.51684  ? 153 THR A CA   1 
ATOM   2121 C C    . THR A 1 139 ? -1.01658  -13.62619 7.73684   1.000 10.74410  ? 153 THR A C    1 
ATOM   2122 O O    . THR A 1 139 ? 0.05719   -13.01875 7.64991   1.000 11.26155  ? 153 THR A O    1 
ATOM   2123 C CB   . THR A 1 139 ? -2.24367  -11.92690 9.07026   1.000 12.57505  ? 153 THR A CB   1 
ATOM   2124 O OG1  . THR A 1 139 ? -3.04894  -11.71482 10.22260  1.000 13.03253  ? 153 THR A OG1  1 
ATOM   2125 C CG2  . THR A 1 139 ? -2.97617  -11.41698 7.84623   1.000 13.85976  ? 153 THR A CG2  1 
ATOM   2126 H H    . THR A 1 139 ? -0.43495  -13.55542 10.20842  0.829 11.90157  ? 153 THR A H    1 
ATOM   2127 H HA   . THR A 1 139 ? -2.75535  -13.89616 8.82041   1.000 13.81510  ? 153 THR A HA   1 
ATOM   2128 H HB   . THR A 1 139 ? -1.41564  -11.42937 9.15822   1.000 15.08495  ? 153 THR A HB   1 
ATOM   2129 H HG1  . THR A 1 139 ? -3.11919  -10.89204 10.37655  1.000 15.63393  ? 153 THR A HG1  1 
ATOM   2130 H HG21 . THR A 1 139 ? -3.28443  -10.50987 7.99801   0.508 16.62661  ? 153 THR A HG21 1 
ATOM   2131 H HG22 . THR A 1 139 ? -2.38368  -11.42376 7.07825   1.000 16.62661  ? 153 THR A HG22 1 
ATOM   2132 H HG23 . THR A 1 139 ? -3.74168  -11.98229 7.65825   1.000 16.62661  ? 153 THR A HG23 1 
ATOM   2133 N N    . VAL A 1 140 ? -1.42590  -14.51317 6.84347   1.000 10.75084  ? 154 VAL A N    1 
ATOM   2134 C CA   . VAL A 1 140 ? -0.67550  -14.83030 5.64271   1.000 11.02522  ? 154 VAL A CA   1 
ATOM   2135 C C    . VAL A 1 140 ? -1.42289  -14.23040 4.46513   1.000 11.84119  ? 154 VAL A C    1 
ATOM   2136 O O    . VAL A 1 140 ? -2.64032  -14.40935 4.34074   1.000 12.83790  ? 154 VAL A O    1 
ATOM   2137 C CB   . VAL A 1 140 ? -0.55730  -16.34895 5.46394   1.000 12.09420  ? 154 VAL A CB   1 
ATOM   2138 C CG1  . VAL A 1 140 ? 0.05615   -16.67818 4.12339   1.000 13.03822  ? 154 VAL A CG1  1 
ATOM   2139 C CG2  . VAL A 1 140 ? 0.25369   -16.94754 6.60227   1.000 13.10167  ? 154 VAL A CG2  1 
ATOM   2140 H H    . VAL A 1 140 ? -2.15879  -14.95745 6.91479   0.411 12.89590  ? 154 VAL A H    1 
ATOM   2141 H HA   . VAL A 1 140 ? 0.21201   -14.44229 5.69434   1.000 13.22516  ? 154 VAL A HA   1 
ATOM   2142 H HB   . VAL A 1 140 ? -1.44261  -16.74473 5.48595   1.000 14.50793  ? 154 VAL A HB   1 
ATOM   2143 H HG11 . VAL A 1 140 ? 0.74222   -16.02312 3.92061   1.000 15.64076  ? 154 VAL A HG11 1 
ATOM   2144 H HG12 . VAL A 1 140 ? 0.44721   -17.56491 4.16426   1.000 15.64076  ? 154 VAL A HG12 1 
ATOM   2145 H HG13 . VAL A 1 140 ? -0.63623  -16.65298 3.44451   1.000 15.64076  ? 154 VAL A HG13 1 
ATOM   2146 H HG21 . VAL A 1 140 ? 0.22485   -17.91484 6.53597   1.000 15.71690  ? 154 VAL A HG21 1 
ATOM   2147 H HG22 . VAL A 1 140 ? 1.17054   -16.63845 6.53341   1.000 15.71690  ? 154 VAL A HG22 1 
ATOM   2148 H HG23 . VAL A 1 140 ? -0.12900  -16.66231 7.44672   1.000 15.71690  ? 154 VAL A HG23 1 
ATOM   2149 N N    . ARG A 1 141 ? -0.70684  -13.54811 3.58063   1.000 11.67727  ? 155 ARG A N    1 
ATOM   2150 C CA   . ARG A 1 141 ? -1.31390  -13.08024 2.34509   1.000 12.87334  ? 155 ARG A CA   1 
ATOM   2151 C C    . ARG A 1 141 ? -1.12844  -14.12341 1.25831   1.000 12.90750  ? 155 ARG A C    1 
ATOM   2152 O O    . ARG A 1 141 ? -0.01292  -14.59727 1.01112   1.000 13.95906  ? 155 ARG A O    1 
ATOM   2153 C CB   . ARG A 1 141 ? -0.72389  -11.75786 1.87842   1.000 13.71932  ? 155 ARG A CB   1 
ATOM   2154 C CG   . ARG A 1 141 ? -1.39972  -10.54701 2.43254   1.000 14.60889  ? 155 ARG A CG   1 
ATOM   2155 C CD   . ARG A 1 141 ? -0.82578  -9.30221  1.81360   1.000 15.34219  ? 155 ARG A CD   1 
ATOM   2156 N NE   . ARG A 1 141 ? -1.57031  -8.10205  2.16829   1.000 16.15909  ? 155 ARG A NE   1 
ATOM   2157 C CZ   . ARG A 1 141 ? -2.65017  -7.68187  1.52995   1.000 17.36664  ? 155 ARG A CZ   1 
ATOM   2158 N NH1  . ARG A 1 141 ? -3.14903  -8.34846  0.49916   1.000 17.78409  ? 155 ARG A NH1  1 
ATOM   2159 N NH2  . ARG A 1 141 ? -3.23631  -6.56215  1.93169   1.000 19.30077  ? 155 ARG A NH2  1 
ATOM   2160 H H    . ARG A 1 141 ? 0.12396   -13.34627 3.67353   1.000 14.00762  ? 155 ARG A H    1 
ATOM   2161 H HA   . ARG A 1 141 ? -2.25998  -12.94140 2.50808   1.000 15.44290  ? 155 ARG A HA   1 
ATOM   2162 H HB2  . ARG A 1 141 ? 0.20713   -11.72281 2.14839   1.000 16.45808  ? 155 ARG A HB2  1 
ATOM   2163 H HB3  . ARG A 1 141 ? -0.79088  -11.71393 0.91174   1.000 16.45808  ? 155 ARG A HB3  1 
ATOM   2164 H HG2  . ARG A 1 141 ? -2.34842  -10.58329 2.23366   1.000 17.52556  ? 155 ARG A HG2  1 
ATOM   2165 H HG3  . ARG A 1 141 ? -1.26317  -10.50767 3.39207   0.760 17.52556  ? 155 ARG A HG3  1 
ATOM   2166 H HD2  . ARG A 1 141 ? 0.08790   -9.18941  2.11915   1.000 18.40553  ? 155 ARG A HD2  1 
ATOM   2167 H HD3  . ARG A 1 141 ? -0.84400  -9.39182  0.84792   0.875 18.40553  ? 155 ARG A HD3  1 
ATOM   2168 H HE   . ARG A 1 141 ? -1.29020  -7.63681  2.83515   1.000 19.38579  ? 155 ARG A HE   1 
ATOM   2169 H HH11 . ARG A 1 141 ? -2.76971  -9.07214  0.23083   1.000 21.33580  ? 155 ARG A HH11 1 
ATOM   2170 H HH12 . ARG A 1 141 ? -3.85212  -8.05742  0.09846   0.342 21.33580  ? 155 ARG A HH12 1 
ATOM   2171 H HH21 . ARG A 1 141 ? -2.91363  -6.12254  2.59669   0.529 23.15581  ? 155 ARG A HH21 1 
ATOM   2172 H HH22 . ARG A 1 141 ? -3.93909  -6.27563  1.52720   1.000 23.15581  ? 155 ARG A HH22 1 
ATOM   2173 N N    . ILE A 1 142 ? -2.23694  -14.45625 0.60548   1.000 13.62765  ? 156 ILE A N    1 
ATOM   2174 C CA   . ILE A 1 142 ? -2.25468  -15.26519 -0.59854  1.000 15.26519  ? 156 ILE A CA   1 
ATOM   2175 C C    . ILE A 1 142 ? -2.72273  -14.44446 -1.79270  1.000 16.65379  ? 156 ILE A C    1 
ATOM   2176 O O    . ILE A 1 142 ? -3.05710  -14.99811 -2.84353  1.000 17.62748  ? 156 ILE A O    1 
ATOM   2177 C CB   . ILE A 1 142 ? -3.08747  -16.54680 -0.41425  1.000 16.74572  ? 156 ILE A CB   1 
ATOM   2178 C CG1  . ILE A 1 142 ? -4.53120  -16.21383 -0.01646  1.000 17.93299  ? 156 ILE A CG1  1 
ATOM   2179 C CG2  . ILE A 1 142 ? -2.44554  -17.44716 0.62661   1.000 17.43230  ? 156 ILE A CG2  1 
ATOM   2180 C CD1  . ILE A 1 142 ? -5.48806  -17.40251 -0.06312  1.000 20.09774  ? 156 ILE A CD1  1 
ATOM   2181 H H    . ILE A 1 142 ? -3.02321  -14.21279 0.85470   1.000 16.34808  ? 156 ILE A H    1 
ATOM   2182 H HA   . ILE A 1 142 ? -1.35004  -15.55807 -0.79024  1.000 18.31312  ? 156 ILE A HA   1 
ATOM   2183 H HB   . ILE A 1 142 ? -3.10988  -17.01379 -1.26414  1.000 20.08975  ? 156 ILE A HB   1 
ATOM   2184 H HG12 . ILE A 1 142 ? -4.53114  -15.87276 0.89160   1.000 21.51448  ? 156 ILE A HG12 1 
ATOM   2185 H HG13 . ILE A 1 142 ? -4.87184  -15.53900 -0.62430  1.000 21.51448  ? 156 ILE A HG13 1 
ATOM   2186 H HG21 . ILE A 1 142 ? -3.00670  -18.22727 0.75864   1.000 20.91366  ? 156 ILE A HG21 1 
ATOM   2187 H HG22 . ILE A 1 142 ? -1.56945  -17.71939 0.31156   0.781 20.91366  ? 156 ILE A HG22 1 
ATOM   2188 H HG23 . ILE A 1 142 ? -2.35998  -16.95653 1.45900   1.000 20.91366  ? 156 ILE A HG23 1 
ATOM   2189 H HD11 . ILE A 1 142 ? -6.39005  -17.08870 0.10673   1.000 24.11218  ? 156 ILE A HD11 1 
ATOM   2190 H HD12 . ILE A 1 142 ? -5.44019  -17.81218 -0.94106  1.000 24.11218  ? 156 ILE A HD12 1 
ATOM   2191 H HD13 . ILE A 1 142 ? -5.22775  -18.04432 0.61601   1.000 24.11218  ? 156 ILE A HD13 1 
ATOM   2192 N N    . GLY A 1 143 ? -2.77503  -13.12748 -1.63882  1.000 17.02508  ? 157 GLY A N    1 
ATOM   2193 C CA   . GLY A 1 143 ? -3.11062  -12.21736 -2.71361  1.000 17.45161  ? 157 GLY A CA   1 
ATOM   2194 C C    . GLY A 1 143 ? -2.70958  -10.82976 -2.27529  1.000 18.15675  ? 157 GLY A C    1 
ATOM   2195 O O    . GLY A 1 143 ? -2.32750  -10.60369 -1.12283  1.000 17.68836  ? 157 GLY A O    1 
ATOM   2196 H H    . GLY A 1 143 ? -2.61437  -12.72618 -0.89535  0.065 20.42499  ? 157 GLY A H    1 
ATOM   2197 H HA2  . GLY A 1 143 ? -2.63113  -12.45473 -3.52271  1.000 20.93683  ? 157 GLY A HA2  1 
ATOM   2198 H HA3  . GLY A 1 143 ? -4.06359  -12.23956 -2.89324  0.645 20.93683  ? 157 GLY A HA3  1 
ATOM   2199 N N    . THR A 1 144 ? -2.79088  -9.89623  -3.22255  1.000 19.08985  ? 158 THR A N    1 
ATOM   2200 C CA   . THR A 1 144 ? -2.47413  -8.50062  -2.95632  1.000 20.84839  ? 158 THR A CA   1 
ATOM   2201 C C    . THR A 1 144 ? -3.71336  -7.64688  -2.76865  1.000 22.50550  ? 158 THR A C    1 
ATOM   2202 O O    . THR A 1 144 ? -3.58752  -6.45943  -2.45944  1.000 24.10633  ? 158 THR A O    1 
ATOM   2203 C CB   . THR A 1 144 ? -1.61082  -7.90507  -4.06677  1.000 21.20369  ? 158 THR A CB   1 
ATOM   2204 O OG1  . THR A 1 144 ? -2.31870  -8.00442  -5.30203  1.000 22.32829  ? 158 THR A OG1  1 
ATOM   2205 C CG2  . THR A 1 144 ? -0.27774  -8.63217  -4.17556  1.000 21.72909  ? 158 THR A CG2  1 
ATOM   2206 H H    . THR A 1 144 ? -3.02981  -10.05161 -4.03395  0.925 22.90271  ? 158 THR A H    1 
ATOM   2207 H HA   . THR A 1 144 ? -1.95033  -8.46612  -2.14063  1.000 25.01295  ? 158 THR A HA   1 
ATOM   2208 H HB   . THR A 1 144 ? -1.41829  -6.97493  -3.87014  1.000 25.43931  ? 158 THR A HB   1 
ATOM   2209 H HG1  . THR A 1 144 ? -3.00809  -7.52511  -5.27745  1.000 26.78883  ? 158 THR A HG1  1 
ATOM   2210 H HG21 . THR A 1 144 ? 0.31783   -8.14633  -4.76731  1.000 26.06980  ? 158 THR A HG21 1 
ATOM   2211 H HG22 . THR A 1 144 ? 0.13507   -8.70088  -3.30048  1.000 26.06980  ? 158 THR A HG22 1 
ATOM   2212 H HG23 . THR A 1 144 ? -0.41458  -9.52465  -4.53003  0.931 26.06980  ? 158 THR A HG23 1 
ATOM   2213 N N    . GLY A 1 145 ? -4.90112  -8.21720  -2.94902  1.000 23.32705  ? 159 GLY A N    1 
ATOM   2214 C CA   . GLY A 1 145 ? -6.13074  -7.48150  -2.76796  1.000 24.81109  ? 159 GLY A CA   1 
ATOM   2215 C C    . GLY A 1 145 ? -6.44414  -7.26868  -1.30330  1.000 26.58901  ? 159 GLY A C    1 
ATOM   2216 O O    . GLY A 1 145 ? -5.73049  -7.71725  -0.40468  1.000 26.33386  ? 159 GLY A O    1 
ATOM   2217 H H    . GLY A 1 145 ? -5.01493  -9.03808  -3.17881  0.920 27.98735  ? 159 GLY A H    1 
ATOM   2218 H HA2  . GLY A 1 145 ? -6.05553  -6.61466  -3.19673  0.410 29.76820  ? 159 GLY A HA2  1 
ATOM   2219 H HA3  . GLY A 1 145 ? -6.86371  -7.97139  -3.17252  0.220 29.76820  ? 159 GLY A HA3  1 
ATOM   2220 N N    . ASP A 1 146 ? -7.54684  -6.57135  -1.05367  1.000 29.01511  ? 160 ASP A N    1 
ATOM   2221 C CA   . ASP A 1 146 ? -7.92261  -6.20038  0.29967   1.000 32.75251  ? 160 ASP A CA   1 
ATOM   2222 C C    . ASP A 1 146 ? -9.09051  -7.00073  0.85244   1.000 31.43748  ? 160 ASP A C    1 
ATOM   2223 O O    . ASP A 1 146 ? -9.33741  -6.94345  2.06256   1.000 32.26942  ? 160 ASP A O    1 
ATOM   2224 C CB   . ASP A 1 146 ? -8.22960  -4.69895  0.36657   1.000 38.65435  ? 160 ASP A CB   1 
ATOM   2225 C CG   . ASP A 1 146 ? -7.02345  -3.85118  0.00966   1.000 43.68571  ? 160 ASP A CG   1 
ATOM   2226 O OD1  . ASP A 1 146 ? -5.88286  -4.31636  0.24163   1.000 45.72830  ? 160 ASP A OD1  1 
ATOM   2227 O OD2  . ASP A 1 146 ? -7.21339  -2.72755  -0.50543  1.000 45.71544  ? 160 ASP A OD2  1 
ATOM   2228 H H    . ASP A 1 146 ? -8.09596  -6.30065  -1.65765  0.010 34.81303  ? 160 ASP A H    1 
ATOM   2229 H HA   . ASP A 1 146 ? -7.17072  -6.36667  0.88951   1.000 39.29791  ? 160 ASP A HA   1 
ATOM   2230 H HB2  . ASP A 1 146 ? -8.94097  -4.49134  -0.25932  0.089 46.38011  ? 160 ASP A HB2  1 
ATOM   2231 H HB3  . ASP A 1 146 ? -8.50387  -4.47004  1.26839   1.000 46.38011  ? 160 ASP A HB3  1 
ATOM   2232 N N    . SER A 1 147 ? -9.79305  -7.76050  0.01817   1.000 29.71147  ? 161 SER A N    1 
ATOM   2233 C CA   . SER A 1 147 ? -10.88558 -8.57123  0.51862   1.000 28.28202  ? 161 SER A CA   1 
ATOM   2234 C C    . SER A 1 147 ? -10.34437 -9.73446  1.34473   1.000 26.53377  ? 161 SER A C    1 
ATOM   2235 O O    . SER A 1 147 ? -9.16965  -10.10267 1.26230   1.000 25.32437  ? 161 SER A O    1 
ATOM   2236 C CB   . SER A 1 147 ? -11.75138 -9.06853  -0.63986  1.000 28.09768  ? 161 SER A CB   1 
ATOM   2237 O OG   . SER A 1 147 ? -11.03837 -9.94914  -1.48715  1.000 29.51975  ? 161 SER A OG   1 
ATOM   2238 H H    . SER A 1 147 ? -9.65605  -7.82055  -0.82872  0.542 35.64866  ? 161 SER A H    1 
ATOM   2239 H HA   . SER A 1 147 ? -11.45660 -8.04295  1.09806   1.000 33.93332  ? 161 SER A HA   1 
ATOM   2240 H HB2  . SER A 1 147 ? -12.51883 -9.53776  -0.27688  1.000 33.71211  ? 161 SER A HB2  1 
ATOM   2241 H HB3  . SER A 1 147 ? -12.04531 -8.30448  -1.16018  1.000 33.71211  ? 161 SER A HB3  1 
ATOM   2242 H HG   . SER A 1 147 ? -10.78942 -10.62502 -1.05493  0.056 35.41859  ? 161 SER A HG   1 
ATOM   2243 N N    . SER A 1 148 ? -11.23100 -10.32882 2.14167   1.000 25.85370  ? 162 SER A N    1 
ATOM   2244 C CA   A SER A 1 148 ? -10.79938 -11.33631 3.10383   0.528 25.87199  ? 162 SER A CA   1 
ATOM   2245 C CA   B SER A 1 148 ? -10.79937 -11.33723 3.10355   0.472 25.71619  ? 162 SER A CA   1 
ATOM   2246 C C    . SER A 1 148 ? -10.16940 -12.54261 2.42390   1.000 25.10425  ? 162 SER A C    1 
ATOM   2247 O O    . SER A 1 148 ? -9.33988  -13.22828 3.02964   1.000 24.38069  ? 162 SER A O    1 
ATOM   2248 C CB   A SER A 1 148 ? -11.98950 -11.77773 3.95293   0.528 27.34583  ? 162 SER A CB   1 
ATOM   2249 C CB   B SER A 1 148 ? -11.98671 -11.78366 3.95372   0.472 26.81553  ? 162 SER A CB   1 
ATOM   2250 O OG   A SER A 1 148 ? -13.01781 -12.30781 3.13674   0.528 28.52234  ? 162 SER A OG   1 
ATOM   2251 O OG   B SER A 1 148 ? -12.56619 -10.68127 4.62236   0.472 27.66857  ? 162 SER A OG   1 
ATOM   2252 H H    . SER A 1 148 ? -12.07640 -10.17115 2.14740   0.304 31.01934  ? 162 SER A H    1 
ATOM   2253 H HA   . SER A 1 148 ? -10.13063 -10.94240 3.68565   1.000 30.85432  ? 162 SER A HA   1 
ATOM   2254 H HB2  A SER A 1 148 ? -11.69706 -12.46064 4.57664   0.528 32.80989  ? 162 SER A HB2  1 
ATOM   2255 H HB2  B SER A 1 148 ? -12.65305 -12.18995 3.37769   0.472 32.17353  ? 162 SER A HB2  1 
ATOM   2256 H HB3  A SER A 1 148 ? -12.33383 -11.01129 4.43760   0.528 32.80989  ? 162 SER A HB3  1 
ATOM   2257 H HB3  B SER A 1 148 ? -11.68027 -12.42710 4.61173   0.472 32.17353  ? 162 SER A HB3  1 
ATOM   2258 H HG   A SER A 1 148 ? -12.74817 -13.00318 2.75026   0.528 34.22170  ? 162 SER A HG   1 
ATOM   2259 H HG   B SER A 1 148 ? -12.84715 -10.12123 4.06288   0.472 33.19717  ? 162 SER A HG   1 
ATOM   2260 N N    . ASP A 1 149 ? -10.54256 -12.82570 1.17998   1.000 25.43939  ? 163 ASP A N    1 
ATOM   2261 C CA   . ASP A 1 149 ? -9.99494  -13.99059 0.49253   1.000 25.76216  ? 163 ASP A CA   1 
ATOM   2262 C C    . ASP A 1 149 ? -8.49936  -13.86416 0.21941   1.000 23.44250  ? 163 ASP A C    1 
ATOM   2263 O O    . ASP A 1 149 ? -7.87541  -14.84830 -0.18214  1.000 24.08608  ? 163 ASP A O    1 
ATOM   2264 C CB   . ASP A 1 149 ? -10.76386 -14.26156 -0.80622  1.000 30.27926  ? 163 ASP A CB   1 
ATOM   2265 C CG   . ASP A 1 149 ? -10.43594 -13.26740 -1.89596  1.000 34.26010  ? 163 ASP A CG   1 
ATOM   2266 O OD1  . ASP A 1 149 ? -10.58553 -12.05149 -1.65472  1.000 34.87543  ? 163 ASP A OD1  1 
ATOM   2267 O OD2  . ASP A 1 149 ? -10.01987 -13.69836 -2.99522  1.000 37.39078  ? 163 ASP A OD2  1 
ATOM   2268 H H    . ASP A 1 149 ? -11.10353 -12.36577 0.71805   1.000 30.52216  ? 163 ASP A H    1 
ATOM   2269 H HA   . ASP A 1 149 ? -10.11938 -14.76940 1.05721   1.000 30.90948  ? 163 ASP A HA   1 
ATOM   2270 H HB2  . ASP A 1 149 ? -10.53646 -15.14735 -1.12958  1.000 36.33000  ? 163 ASP A HB2  1 
ATOM   2271 H HB3  . ASP A 1 149 ? -11.71572 -14.20791 -0.62740  1.000 36.33000  ? 163 ASP A HB3  1 
ATOM   2272 N N    . ASN A 1 150 ? -7.92221  -12.68607 0.40648   1.000 20.81517  ? 164 ASN A N    1 
ATOM   2273 C CA   . ASN A 1 150 ? -6.48048  -12.51780 0.24652   1.000 19.25922  ? 164 ASN A CA   1 
ATOM   2274 C C    . ASN A 1 150 ? -5.67736  -12.95152 1.46192   1.000 17.19154  ? 164 ASN A C    1 
ATOM   2275 O O    . ASN A 1 150 ? -4.44653  -12.92112 1.40112   1.000 16.40046  ? 164 ASN A O    1 
ATOM   2276 C CB   . ASN A 1 150 ? -6.16611  -11.05632 -0.03677  1.000 20.08227  ? 164 ASN A CB   1 
ATOM   2277 C CG   . ASN A 1 150 ? -6.68927  -10.62329 -1.37517  1.000 21.13769  ? 164 ASN A CG   1 
ATOM   2278 O OD1  . ASN A 1 150 ? -6.03050  -10.82262 -2.38756  1.000 21.12655  ? 164 ASN A OD1  1 
ATOM   2279 N ND2  . ASN A 1 150 ? -7.89824  -10.07798 -1.40057  1.000 22.20844  ? 164 ASN A ND2  1 
ATOM   2280 H H    . ASN A 1 150 ? -8.34057  -11.96758 0.62636   1.000 24.97309  ? 164 ASN A H    1 
ATOM   2281 H HA   . ASN A 1 150 ? -6.19790  -13.05954 -0.50686  1.000 23.10595  ? 164 ASN A HA   1 
ATOM   2282 H HB2  . ASN A 1 150 ? -6.57855  -10.50258 0.64454   1.000 24.09361  ? 164 ASN A HB2  1 
ATOM   2283 H HB3  . ASN A 1 150 ? -5.20453  -10.92898 -0.03049  1.000 24.09361  ? 164 ASN A HB3  1 
ATOM   2284 H HD21 . ASN A 1 150 ? -8.34414  -9.98656  -0.67090  1.000 26.64502  ? 164 ASN A HD21 1 
ATOM   2285 H HD22 . ASN A 1 150 ? -8.23613  -9.81586  -2.14670  1.000 26.64502  ? 164 ASN A HD22 1 
ATOM   2286 N N    . PHE A 1 151 ? -6.33484  -13.32415 2.55245   1.000 16.06271  ? 165 PHE A N    1 
ATOM   2287 C CA   . PHE A 1 151 ? -5.65925  -13.60822 3.81390   1.000 15.88565  ? 165 PHE A CA   1 
ATOM   2288 C C    . PHE A 1 151 ? -6.05865  -14.97488 4.33889   1.000 15.76776  ? 165 PHE A C    1 
ATOM   2289 O O    . PHE A 1 151 ? -7.20407  -15.41832 4.18169   1.000 17.60678  ? 165 PHE A O    1 
ATOM   2290 C CB   . PHE A 1 151 ? -6.03948  -12.57173 4.87763   1.000 16.74637  ? 165 PHE A CB   1 
ATOM   2291 C CG   . PHE A 1 151 ? -5.83505  -11.15566 4.43133   1.000 17.11799  ? 165 PHE A CG   1 
ATOM   2292 C CD1  . PHE A 1 151 ? -4.58561  -10.56130 4.49790   1.000 17.57572  ? 165 PHE A CD1  1 
ATOM   2293 C CD2  . PHE A 1 151 ? -6.89213  -10.42125 3.92236   1.000 19.17951  ? 165 PHE A CD2  1 
ATOM   2294 C CE1  . PHE A 1 151 ? -4.40669  -9.24701  4.07648   1.000 19.46389  ? 165 PHE A CE1  1 
ATOM   2295 C CE2  . PHE A 1 151 ? -6.71183  -9.11479  3.49787   1.000 20.63882  ? 165 PHE A CE2  1 
ATOM   2296 C CZ   . PHE A 1 151 ? -5.47297  -8.52996  3.57321   1.000 20.83326  ? 165 PHE A CZ   1 
ATOM   2297 H H    . PHE A 1 151 ? -7.18854  -13.42158 2.58841   1.000 19.27014  ? 165 PHE A H    1 
ATOM   2298 H HA   . PHE A 1 151 ? -4.70149  -13.60196 3.66047   1.000 19.05767  ? 165 PHE A HA   1 
ATOM   2299 H HB2  . PHE A 1 151 ? -6.97735  -12.68090 5.09986   1.000 20.09053  ? 165 PHE A HB2  1 
ATOM   2300 H HB3  . PHE A 1 151 ? -5.49274  -12.71692 5.66561   1.000 20.09053  ? 165 PHE A HB3  1 
ATOM   2301 H HD1  . PHE A 1 151 ? -3.86152  -11.04369 4.82637   0.596 21.08576  ? 165 PHE A HD1  1 
ATOM   2302 H HD2  . PHE A 1 151 ? -7.73496  -10.81009 3.86454   0.718 23.01031  ? 165 PHE A HD2  1 
ATOM   2303 H HE1  . PHE A 1 151 ? -3.56705  -8.85129  4.13415   1.000 23.35156  ? 165 PHE A HE1  1 
ATOM   2304 H HE2  . PHE A 1 151 ? -7.43243  -8.63297  3.16097   1.000 24.76148  ? 165 PHE A HE2  1 
ATOM   2305 H HZ   . PHE A 1 151 ? -5.35228  -7.65363  3.28620   1.000 24.99481  ? 165 PHE A HZ   1 
ATOM   2306 N N    . VAL A 1 152 ? -5.10357  -15.62205 5.00353   1.000 14.31129  ? 166 VAL A N    1 
ATOM   2307 C CA   . VAL A 1 152 ? -5.37482  -16.76734 5.85600   1.000 13.24195  ? 166 VAL A CA   1 
ATOM   2308 C C    . VAL A 1 152 ? -4.93756  -16.36034 7.25062   1.000 12.72554  ? 166 VAL A C    1 
ATOM   2309 O O    . VAL A 1 152 ? -3.75122  -16.08406 7.47997   1.000 12.57295  ? 166 VAL A O    1 
ATOM   2310 C CB   . VAL A 1 152 ? -4.63463  -18.03276 5.39354   1.000 14.66709  ? 166 VAL A CB   1 
ATOM   2311 C CG1  . VAL A 1 152 ? -4.99293  -19.20850 6.27321   1.000 15.45221  ? 166 VAL A CG1  1 
ATOM   2312 C CG2  . VAL A 1 152 ? -4.93201  -18.33077 3.93235   1.000 16.23406  ? 166 VAL A CG2  1 
ATOM   2313 H H    . VAL A 1 152 ? -4.27135  -15.40745 4.97275   0.576 17.16845  ? 166 VAL A H    1 
ATOM   2314 H HA   . VAL A 1 152 ? -6.32305  -16.97164 5.85273   1.000 15.88523  ? 166 VAL A HA   1 
ATOM   2315 H HB   . VAL A 1 152 ? -3.67972  -17.88179 5.47266   1.000 17.59540  ? 166 VAL A HB   1 
ATOM   2316 H HG11 . VAL A 1 152 ? -5.94373  -19.18238 6.46347   1.000 18.53754  ? 166 VAL A HG11 1 
ATOM   2317 H HG12 . VAL A 1 152 ? -4.77116  -20.03020 5.80789   1.000 18.53754  ? 166 VAL A HG12 1 
ATOM   2318 H HG13 . VAL A 1 152 ? -4.48848  -19.14988 7.09965   0.917 18.53754  ? 166 VAL A HG13 1 
ATOM   2319 H HG21 . VAL A 1 152 ? -4.49812  -19.16230 3.68499   1.000 19.47576  ? 166 VAL A HG21 1 
ATOM   2320 H HG22 . VAL A 1 152 ? -5.89160  -18.41080 3.81532   1.000 19.47576  ? 166 VAL A HG22 1 
ATOM   2321 H HG23 . VAL A 1 152 ? -4.59160  -17.60487 3.38637   1.000 19.47576  ? 166 VAL A HG23 1 
ATOM   2322 N N    . LYS A 1 153 ? -5.89000  -16.27398 8.16955   1.000 13.38325  ? 167 LYS A N    1 
ATOM   2323 C CA   A LYS A 1 153 ? -5.63090  -15.85686 9.54207   0.527 13.86625  ? 167 LYS A CA   1 
ATOM   2324 C CA   B LYS A 1 153 ? -5.62902  -15.85653 9.54071   0.473 13.97585  ? 167 LYS A CA   1 
ATOM   2325 C C    . LYS A 1 153 ? -5.85511  -17.04160 10.46816  1.000 14.05361  ? 167 LYS A C    1 
ATOM   2326 O O    . LYS A 1 153 ? -6.85497  -17.75271 10.34419  1.000 15.81333  ? 167 LYS A O    1 
ATOM   2327 C CB   A LYS A 1 153 ? -6.53672  -14.68435 9.93400   0.527 15.65802  ? 167 LYS A CB   1 
ATOM   2328 C CB   B LYS A 1 153 ? -6.51363  -14.66243 9.91727   0.473 15.65918  ? 167 LYS A CB   1 
ATOM   2329 C CG   A LYS A 1 153 ? -6.23105  -13.39468 9.18667   0.527 18.12815  ? 167 LYS A CG   1 
ATOM   2330 C CG   B LYS A 1 153 ? -6.24837  -13.43733 9.04353   0.473 18.10212  ? 167 LYS A CG   1 
ATOM   2331 C CD   A LYS A 1 153 ? -7.14470  -12.26172 9.62067   0.527 20.80898  ? 167 LYS A CD   1 
ATOM   2332 C CD   B LYS A 1 153 ? -6.94846  -12.18403 9.54449   0.473 20.63292  ? 167 LYS A CD   1 
ATOM   2333 C CE   A LYS A 1 153 ? -6.66514  -10.91516 9.09844   0.527 22.15362  ? 167 LYS A CE   1 
ATOM   2334 C CE   B LYS A 1 153 ? -6.46747  -10.94496 8.80022   0.473 22.40075  ? 167 LYS A CE   1 
ATOM   2335 N NZ   A LYS A 1 153 ? -5.61580  -10.30462 9.98146   0.527 21.64199  ? 167 LYS A NZ   1 
ATOM   2336 N NZ   B LYS A 1 153 ? -7.22146  -9.72094  9.19622   0.473 22.84465  ? 167 LYS A NZ   1 
ATOM   2337 H H    . LYS A 1 153 ? -6.71593  -16.45739 8.01525   0.561 16.05479  ? 167 LYS A H    1 
ATOM   2338 H HA   . LYS A 1 153 ? -4.70967  -15.56756 9.63454   1.000 16.76592  ? 167 LYS A HA   1 
ATOM   2339 H HB2  A LYS A 1 153 ? -7.45712  -14.92495 9.74460   0.527 18.78451  ? 167 LYS A HB2  1 
ATOM   2340 H HB2  B LYS A 1 153 ? -7.44477  -14.91246 9.81066   0.473 18.78591  ? 167 LYS A HB2  1 
ATOM   2341 H HB3  A LYS A 1 153 ? -6.42775  -14.50987 10.88193  0.527 18.78451  ? 167 LYS A HB3  1 
ATOM   2342 H HB3  B LYS A 1 153 ? -6.33927  -14.41797 10.83962  0.473 18.78591  ? 167 LYS A HB3  1 
ATOM   2343 H HG2  A LYS A 1 153 ? -5.31471  -13.13094 9.36461   0.527 21.74867  ? 167 LYS A HG2  1 
ATOM   2344 H HG2  B LYS A 1 153 ? -5.29470  -13.26063 9.02973   0.473 21.71743  ? 167 LYS A HG2  1 
ATOM   2345 H HG3  A LYS A 1 153 ? -6.35620  -13.53834 8.23557   0.527 21.74867  ? 167 LYS A HG3  1 
ATOM   2346 H HG3  B LYS A 1 153 ? -6.56558  -13.61674 8.14459   0.473 21.71743  ? 167 LYS A HG3  1 
ATOM   2347 H HD2  A LYS A 1 153 ? -8.03725  -12.42046 9.27561   0.527 24.96567  ? 167 LYS A HD2  1 
ATOM   2348 H HD2  B LYS A 1 153 ? -7.90441  -12.27198 9.40550   0.473 24.75440  ? 167 LYS A HD2  1 
ATOM   2349 H HD3  A LYS A 1 153 ? -7.16595  -12.22116 10.58959  0.527 24.96567  ? 167 LYS A HD3  1 
ATOM   2350 H HD3  B LYS A 1 153 ? -6.75998  -12.06564 10.48861  0.473 24.75440  ? 167 LYS A HD3  1 
ATOM   2351 H HE2  A LYS A 1 153 ? -6.28407  -11.03397 8.21438   0.527 26.57924  ? 167 LYS A HE2  1 
ATOM   2352 H HE2  B LYS A 1 153 ? -5.52919  -10.79890 8.99818   0.473 26.87579  ? 167 LYS A HE2  1 
ATOM   2353 H HE3  A LYS A 1 153 ? -7.41717  -10.30396 9.05616   0.527 26.57924  ? 167 LYS A HE3  1 
ATOM   2354 H HE3  B LYS A 1 153 ? -6.58850  -11.07905 7.84719   0.473 26.87579  ? 167 LYS A HE3  1 
ATOM   2355 H HZ1  A LYS A 1 153 ? -5.21106  -9.63603  9.55570   0.527 25.96528  ? 167 LYS A HZ1  1 
ATOM   2356 H HZ1  B LYS A 1 153 ? -6.75278  -8.99378  8.98724   0.473 27.40847  ? 167 LYS A HZ1  1 
ATOM   2357 H HZ2  A LYS A 1 153 ? -5.98955  -9.98930  10.72509  0.527 25.96528  ? 167 LYS A HZ2  1 
ATOM   2358 H HZ2  B LYS A 1 153 ? -8.00249  -9.69344  8.77038   0.473 27.40847  ? 167 LYS A HZ2  1 
ATOM   2359 H HZ3  A LYS A 1 153 ? -5.00847  -10.91713 10.20074  0.527 25.96528  ? 167 LYS A HZ3  1 
ATOM   2360 H HZ3  B LYS A 1 153 ? -7.37088  -9.72600  10.07358  0.473 27.40847  ? 167 LYS A HZ3  1 
ATOM   2361 N N    . THR A 1 154 ? -4.91623  -17.25655 11.38743  1.000 12.80341  ? 168 THR A N    1 
ATOM   2362 C CA   . THR A 1 154 ? -4.92972  -18.43110 12.24306  1.000 13.73281  ? 168 THR A CA   1 
ATOM   2363 C C    . THR A 1 154 ? -4.65625  -18.02867 13.68163  1.000 12.89616  ? 168 THR A C    1 
ATOM   2364 O O    . THR A 1 154 ? -3.73058  -17.25815 13.96086  1.000 12.57973  ? 168 THR A O    1 
ATOM   2365 C CB   . THR A 1 154 ? -3.84614  -19.41996 11.77846  1.000 14.85688  ? 168 THR A CB   1 
ATOM   2366 O OG1  . THR A 1 154 ? -4.00672  -19.66607 10.37960  1.000 16.03757  ? 168 THR A OG1  1 
ATOM   2367 C CG2  . THR A 1 154 ? -3.91293  -20.73514 12.52538  1.000 15.86094  ? 168 THR A CG2  1 
ATOM   2368 H H    . THR A 1 154 ? -4.25442  -16.72698 11.53293  1.000 15.35899  ? 168 THR A H    1 
ATOM   2369 H HA   . THR A 1 154 ? -5.80145  -18.85554 12.21392  1.000 16.47426  ? 168 THR A HA   1 
ATOM   2370 H HB   . THR A 1 154 ? -2.97526  -19.03237 11.95801  1.000 17.82315  ? 168 THR A HB   1 
ATOM   2371 H HG1  . THR A 1 154 ? -3.37207  -20.13774 10.09616  1.000 19.23998  ? 168 THR A HG1  1 
ATOM   2372 H HG21 . THR A 1 154 ? -3.34865  -21.39303 12.08987  1.000 19.02802  ? 168 THR A HG21 1 
ATOM   2373 H HG22 . THR A 1 154 ? -3.60830  -20.61404 13.43830  1.000 19.02802  ? 168 THR A HG22 1 
ATOM   2374 H HG23 . THR A 1 154 ? -4.82576  -21.06296 12.53899  1.000 19.02802  ? 168 THR A HG23 1 
ATOM   2375 N N    . HIS A 1 155 ? -5.43883  -18.59081 14.59742  1.000 13.17320  ? 169 HIS A N    1 
ATOM   2376 C CA   . HIS A 1 155 ? -5.14408  -18.50800 16.02576  1.000 13.08391  ? 169 HIS A CA   1 
ATOM   2377 C C    . HIS A 1 155 ? -3.97370  -19.43165 16.30974  1.000 13.11568  ? 169 HIS A C    1 
ATOM   2378 O O    . HIS A 1 155 ? -4.09645  -20.64660 16.17024  1.000 15.98741  ? 169 HIS A O    1 
ATOM   2379 C CB   . HIS A 1 155 ? -6.37736  -18.94453 16.81577  1.000 14.62033  ? 169 HIS A CB   1 
ATOM   2380 C CG   . HIS A 1 155 ? -6.14379  -19.05046 18.28845  1.000 15.67596  ? 169 HIS A CG   1 
ATOM   2381 N ND1  . HIS A 1 155 ? -5.69346  -20.20714 18.88549  1.000 18.17910  ? 169 HIS A ND1  1 
ATOM   2382 C CD2  . HIS A 1 155 ? -6.28665  -18.14576 19.28540  1.000 18.40332  ? 169 HIS A CD2  1 
ATOM   2383 C CE1  . HIS A 1 155 ? -5.58579  -20.01556 20.18933  1.000 18.16285  ? 169 HIS A CE1  1 
ATOM   2384 N NE2  . HIS A 1 155 ? -5.93939  -18.77387 20.45795  1.000 18.49608  ? 169 HIS A NE2  1 
ATOM   2385 H H    . HIS A 1 155 ? -6.15497  -19.03112 14.41614  0.695 15.80273  ? 169 HIS A H    1 
ATOM   2386 H HA   . HIS A 1 155 ? -4.91390  -17.60137 16.28256  1.000 15.69558  ? 169 HIS A HA   1 
ATOM   2387 H HB2  . HIS A 1 155 ? -7.08412  -18.29542 16.67420  1.000 17.53929  ? 169 HIS A HB2  1 
ATOM   2388 H HB3  . HIS A 1 155 ? -6.65902  -19.81642 16.49738  1.000 17.53929  ? 169 HIS A HB3  1 
ATOM   2389 H HD2  . HIS A 1 155 ? -6.56735  -17.26385 19.19409  1.000 22.07888  ? 169 HIS A HD2  1 
ATOM   2390 H HE1  . HIS A 1 155 ? -5.30794  -20.64880 20.81119  1.000 21.79032  ? 169 HIS A HE1  1 
ATOM   2391 H HE2  . HIS A 1 155 ? -5.95088  -18.41531 21.23955  0.715 22.19018  ? 169 HIS A HE2  1 
ATOM   2392 N N    . LEU A 1 156 ? -2.82614  -18.87168 16.68359  1.000 12.31074  ? 170 LEU A N    1 
ATOM   2393 C CA   . LEU A 1 156 ? -1.65132  -19.68699 16.97113  1.000 12.70244  ? 170 LEU A CA   1 
ATOM   2394 C C    . LEU A 1 156 ? -1.64322  -20.18337 18.41099  1.000 13.61962  ? 170 LEU A C    1 
ATOM   2395 O O    . LEU A 1 156 ? -1.40676  -21.36839 18.65824  1.000 15.82665  ? 170 LEU A O    1 
ATOM   2396 C CB   . LEU A 1 156 ? -0.35732  -18.91756 16.69593  1.000 12.52221  ? 170 LEU A CB   1 
ATOM   2397 C CG   . LEU A 1 156 ? -0.19144  -18.37207 15.27924  1.000 12.81437  ? 170 LEU A CG   1 
ATOM   2398 C CD1  . LEU A 1 156 ? 1.17403   -17.71378 15.14735  1.000 13.51507  ? 170 LEU A CD1  1 
ATOM   2399 C CD2  . LEU A 1 156 ? -0.40419  -19.44906 14.22276  1.000 15.11453  ? 170 LEU A CD2  1 
ATOM   2400 H H    . LEU A 1 156 ? -2.70374  -18.02562 16.77737  1.000 14.76778  ? 170 LEU A H    1 
ATOM   2401 H HA   . LEU A 1 156 ? -1.67403  -20.44981 16.37239  0.951 15.23782  ? 170 LEU A HA   1 
ATOM   2402 H HB2  . LEU A 1 156 ? -0.32104  -18.16052 17.30129  1.000 15.02154  ? 170 LEU A HB2  1 
ATOM   2403 H HB3  . LEU A 1 156 ? 0.38998   -19.51275 16.86386  1.000 15.02154  ? 170 LEU A HB3  1 
ATOM   2404 H HG   . LEU A 1 156 ? -0.87407  -17.70307 15.11382  1.000 15.37214  ? 170 LEU A HG   1 
ATOM   2405 H HD11 . LEU A 1 156 ? 1.20077   -16.92602 15.71270  1.000 16.21298  ? 170 LEU A HD11 1 
ATOM   2406 H HD12 . LEU A 1 156 ? 1.85671   -18.34410 15.42581  0.887 16.21298  ? 170 LEU A HD12 1 
ATOM   2407 H HD13 . LEU A 1 156 ? 1.31480   -17.46134 14.22141  1.000 16.21298  ? 170 LEU A HD13 1 
ATOM   2408 H HD21 . LEU A 1 156 ? 0.19428   -20.19085 14.40301  1.000 18.13233  ? 170 LEU A HD21 1 
ATOM   2409 H HD22 . LEU A 1 156 ? -1.32537  -19.75061 14.26024  1.000 18.13233  ? 170 LEU A HD22 1 
ATOM   2410 H HD23 . LEU A 1 156 ? -0.21377  -19.07543 13.34810  1.000 18.13233  ? 170 LEU A HD23 1 
ATOM   2411 N N    . ALA A 1 157 ? -1.90402  -19.28944 19.35814  1.000 12.72553  ? 171 ALA A N    1 
ATOM   2412 C CA   . ALA A 1 157 ? -1.82349  -19.61376 20.77217  1.000 12.80004  ? 171 ALA A CA   1 
ATOM   2413 C C    . ALA A 1 157 ? -2.37670  -18.43759 21.55096  1.000 13.04668  ? 171 ALA A C    1 
ATOM   2414 O O    . ALA A 1 157 ? -2.22770  -17.28968 21.14256  1.000 15.25824  ? 171 ALA A O    1 
ATOM   2415 C CB   . ALA A 1 157 ? -0.37080  -19.85520 21.19601  1.000 14.52264  ? 171 ALA A CB   1 
ATOM   2416 H H    . ALA A 1 157 ? -2.13338  -18.47533 19.20250  1.000 15.26552  ? 171 ALA A H    1 
ATOM   2417 H HA   . ALA A 1 157 ? -2.34893  -20.40694 20.96105  0.788 15.35494  ? 171 ALA A HA   1 
ATOM   2418 H HB1  . ALA A 1 157 ? 0.12845   -19.02947 21.09700  1.000 17.42206  ? 171 ALA A HB1  1 
ATOM   2419 H HB2  . ALA A 1 157 ? -0.35565  -20.14183 22.12257  0.279 17.42206  ? 171 ALA A HB2  1 
ATOM   2420 H HB3  . ALA A 1 157 ? 0.01291   -20.54358 20.63050  0.461 17.42206  ? 171 ALA A HB3  1 
ATOM   2421 N N    . ASP A 1 158 ? -2.97025  -18.72146 22.69712  1.000 13.51461  ? 172 ASP A N    1 
ATOM   2422 C CA   . ASP A 1 158 ? -3.27737  -17.63556 23.60874  1.000 14.43155  ? 172 ASP A CA   1 
ATOM   2423 C C    . ASP A 1 158 ? -1.97711  -17.07703 24.17420  1.000 13.61430  ? 172 ASP A C    1 
ATOM   2424 O O    . ASP A 1 158 ? -0.98737  -17.79813 24.36324  1.000 14.54903  ? 172 ASP A O    1 
ATOM   2425 C CB   . ASP A 1 158 ? -4.16383  -18.12827 24.74614  1.000 17.28164  ? 172 ASP A CB   1 
ATOM   2426 C CG   . ASP A 1 158 ? -5.59778  -18.40937 24.29249  1.000 20.94182  ? 172 ASP A CG   1 
ATOM   2427 O OD1  . ASP A 1 158 ? -5.99103  -17.98783 23.17146  1.000 21.36494  ? 172 ASP A OD1  1 
ATOM   2428 O OD2  . ASP A 1 158 ? -6.33820  -19.04815 25.06846  1.000 25.12443  ? 172 ASP A OD2  1 
ATOM   2429 H H    . ASP A 1 158 ? -3.19791  -19.50741 22.96180  0.764 16.21242  ? 172 ASP A H    1 
ATOM   2430 H HA   . ASP A 1 158 ? -3.75709  -16.93181 23.14452  1.000 17.31275  ? 172 ASP A HA   1 
ATOM   2431 H HB2  . ASP A 1 158 ? -3.79416  -18.95128 25.10238  1.000 20.73286  ? 172 ASP A HB2  1 
ATOM   2432 H HB3  . ASP A 1 158 ? -4.19502  -17.45100 25.43985  0.212 20.73286  ? 172 ASP A HB3  1 
ATOM   2433 N N    . ARG A 1 159 ? -1.97173  -15.77372 24.44718  1.000 13.73942  ? 173 ARG A N    1 
ATOM   2434 C CA   . ARG A 1 159 ? -0.78343  -15.16675 25.02649  1.000 13.37279  ? 173 ARG A CA   1 
ATOM   2435 C C    . ARG A 1 159 ? -0.48017  -15.78374 26.38510  1.000 14.23780  ? 173 ARG A C    1 
ATOM   2436 O O    . ARG A 1 159 ? -1.37210  -15.97245 27.21235  1.000 15.70298  ? 173 ARG A O    1 
ATOM   2437 C CB   . ARG A 1 159 ? -0.99273  -13.66675 25.19198  1.000 13.44095  ? 173 ARG A CB   1 
ATOM   2438 C CG   . ARG A 1 159 ? 0.26037   -12.95016 25.64739  1.000 13.75959  ? 173 ARG A CG   1 
ATOM   2439 C CD   . ARG A 1 159 ? 0.00250   -11.49116 25.96585  1.000 14.42929  ? 173 ARG A CD   1 
ATOM   2440 N NE   . ARG A 1 159 ? -0.97766  -11.36129 27.03040  1.000 15.55254  ? 173 ARG A NE   1 
ATOM   2441 C CZ   . ARG A 1 159 ? -0.70933  -11.52645 28.31400  1.000 16.68936  ? 173 ARG A CZ   1 
ATOM   2442 N NH1  . ARG A 1 159 ? 0.53323   -11.66595 28.74838  1.000 16.54787  ? 173 ARG A NH1  1 
ATOM   2443 N NH2  . ARG A 1 159 ? -1.71130  -11.55132 29.18580  1.000 18.80941  ? 173 ARG A NH2  1 
ATOM   2444 H H    . ARG A 1 159 ? -2.62765  -15.23493 24.30907  1.000 16.48220  ? 173 ARG A H    1 
ATOM   2445 H HA   . ARG A 1 159 ? -0.02780  -15.31658 24.43702  1.000 16.04224  ? 173 ARG A HA   1 
ATOM   2446 H HB2  . ARG A 1 159 ? -1.26235  -13.28935 24.34006  0.328 16.12403  ? 173 ARG A HB2  1 
ATOM   2447 H HB3  . ARG A 1 159 ? -1.68387  -13.51536 25.85553  1.000 16.12403  ? 173 ARG A HB3  1 
ATOM   2448 H HG2  . ARG A 1 159 ? 0.59895   -13.37877 26.44899  1.000 16.50641  ? 173 ARG A HG2  1 
ATOM   2449 H HG3  . ARG A 1 159 ? 0.92541   -12.99225 24.94252  1.000 16.50641  ? 173 ARG A HG3  1 
ATOM   2450 H HD2  . ARG A 1 159 ? 0.82820   -11.07188 26.25449  1.000 17.31004  ? 173 ARG A HD2  1 
ATOM   2451 H HD3  . ARG A 1 159 ? -0.33892  -11.04282 25.17634  0.473 17.31004  ? 173 ARG A HD3  1 
ATOM   2452 H HE   . ARG A 1 159 ? -1.78544  -11.16400 26.81094  0.664 18.65794  ? 173 ARG A HE   1 
ATOM   2453 H HH11 . ARG A 1 159 ? 1.18793   -11.65021 28.19095  0.953 19.85233  ? 173 ARG A HH11 1 
ATOM   2454 H HH12 . ARG A 1 159 ? 0.68583   -11.77232 29.58802  0.313 19.85233  ? 173 ARG A HH12 1 
ATOM   2455 H HH21 . ARG A 1 159 ? -2.52159  -11.46061 28.91232  1.000 22.56618  ? 173 ARG A HH21 1 
ATOM   2456 H HH22 . ARG A 1 159 ? -1.54968  -11.65814 30.02370  1.000 22.56618  ? 173 ARG A HH22 1 
ATOM   2457 N N    . THR A 1 160 ? 0.79394   -16.07338 26.62871  1.000 13.76437  ? 174 THR A N    1 
ATOM   2458 C CA   . THR A 1 160 ? 1.23824   -16.59439 27.91453  1.000 14.86078  ? 174 THR A CA   1 
ATOM   2459 C C    . THR A 1 160 ? 2.03859   -15.54422 28.67026  1.000 15.14190  ? 174 THR A C    1 
ATOM   2460 O O    . THR A 1 160 ? 2.65948   -14.65910 28.08211  1.000 15.97966  ? 174 THR A O    1 
ATOM   2461 C CB   . THR A 1 160 ? 2.09329   -17.85366 27.74654  1.000 15.18661  ? 174 THR A CB   1 
ATOM   2462 O OG1  . THR A 1 160 ? 3.23437   -17.57498 26.91764  1.000 14.89738  ? 174 THR A OG1  1 
ATOM   2463 C CG2  . THR A 1 160 ? 1.27760   -18.96914 27.12765  1.000 16.07161  ? 174 THR A CG2  1 
ATOM   2464 H H    . THR A 1 160 ? 1.42762   -15.97466 26.05573  1.000 16.51213  ? 174 THR A H    1 
ATOM   2465 H HA   . THR A 1 160 ? 0.45651   -16.82289 28.44139  1.000 17.82783  ? 174 THR A HA   1 
ATOM   2466 H HB   . THR A 1 160 ? 2.40344   -18.14556 28.61803  1.000 18.21883  ? 174 THR A HB   1 
ATOM   2467 H HG1  . THR A 1 160 ? 3.72619   -17.00381 27.28842  0.359 17.87175  ? 174 THR A HG1  1 
ATOM   2468 H HG21 . THR A 1 160 ? 1.82857   -19.75935 27.01408  1.000 19.28082  ? 174 THR A HG21 1 
ATOM   2469 H HG22 . THR A 1 160 ? 0.52677   -19.18865 27.70121  0.357 19.28082  ? 174 THR A HG22 1 
ATOM   2470 H HG23 . THR A 1 160 ? 0.94129   -18.69263 26.26085  1.000 19.28082  ? 174 THR A HG23 1 
ATOM   2471 N N    . ALA A 1 161 ? 2.04258   -15.67203 29.99422  1.000 15.32231  ? 175 ALA A N    1 
ATOM   2472 C CA   . ALA A 1 161 ? 2.91427   -14.82781 30.80269  1.000 16.24324  ? 175 ALA A CA   1 
ATOM   2473 C C    . ALA A 1 161 ? 4.38051   -15.08335 30.48390  1.000 15.38013  ? 175 ALA A C    1 
ATOM   2474 O O    . ALA A 1 161 ? 5.18526   -14.14565 30.41455  1.000 16.56682  ? 175 ALA A O    1 
ATOM   2475 C CB   . ALA A 1 161 ? 2.65878   -15.09269 32.28222  1.000 17.38255  ? 175 ALA A CB   1 
ATOM   2476 H H    . ALA A 1 161 ? 1.56064   -16.22779 30.43972  1.000 18.38167  ? 175 ALA A H    1 
ATOM   2477 H HA   . ALA A 1 161 ? 2.71359   -13.89871 30.60929  1.000 19.48678  ? 175 ALA A HA   1 
ATOM   2478 H HB1  . ALA A 1 161 ? 2.86839   -16.01932 32.47795  1.000 20.85395  ? 175 ALA A HB1  1 
ATOM   2479 H HB2  . ALA A 1 161 ? 3.22390   -14.50710 32.81007  1.000 20.85395  ? 175 ALA A HB2  1 
ATOM   2480 H HB3  . ALA A 1 161 ? 1.72528   -14.91623 32.47803  1.000 20.85395  ? 175 ALA A HB3  1 
ATOM   2481 N N    . GLY A 1 162 ? 4.75607   -16.34683 30.34186  1.000 15.41555  ? 176 GLY A N    1 
ATOM   2482 C CA   . GLY A 1 162 ? 6.13769   -16.68770 30.09201  1.000 15.18936  ? 176 GLY A CA   1 
ATOM   2483 C C    . GLY A 1 162 ? 6.50155   -16.62319 28.62556  1.000 14.05064  ? 176 GLY A C    1 
ATOM   2484 O O    . GLY A 1 162 ? 5.66096   -16.41725 27.74800  1.000 14.21223  ? 176 GLY A O    1 
ATOM   2485 H H    . GLY A 1 162 ? 4.22517   -17.02190 30.38683  1.000 18.49355  ? 176 GLY A H    1 
ATOM   2486 H HA2  . GLY A 1 162 ? 6.71090   -16.07181 30.57472  1.000 18.22213  ? 176 GLY A HA2  1 
ATOM   2487 H HA3  . GLY A 1 162 ? 6.30629   -17.58931 30.40757  0.753 18.22213  ? 176 GLY A HA3  1 
ATOM   2488 N N    . ALA A 1 163 ? 7.79060   -16.83341 28.37055  1.000 13.72082  ? 177 ALA A N    1 
ATOM   2489 C CA   . ALA A 1 163 ? 8.29691   -16.79631 27.00526  1.000 13.12624  ? 177 ALA A CA   1 
ATOM   2490 C C    . ALA A 1 163 ? 7.62241   -17.85271 26.14459  1.000 12.67132  ? 177 ALA A C    1 
ATOM   2491 O O    . ALA A 1 163 ? 7.32950   -18.96403 26.59437  1.000 14.07804  ? 177 ALA A O    1 
ATOM   2492 C CB   . ALA A 1 163 ? 9.80530   -17.03810 27.00078  1.000 14.29352  ? 177 ALA A CB   1 
ATOM   2493 H H    . ALA A 1 163 ? 8.38777   -16.99840 28.96701  1.000 16.45987  ? 177 ALA A H    1 
ATOM   2494 H HA   . ALA A 1 163 ? 8.11118   -15.92278 26.62664  1.000 15.74638  ? 177 ALA A HA   1 
ATOM   2495 H HB1  . ALA A 1 163 ? 10.11874  -17.06095 26.08310  1.000 17.14712  ? 177 ALA A HB1  1 
ATOM   2496 H HB2  . ALA A 1 163 ? 10.24204  -16.31774 27.48165  1.000 17.14712  ? 177 ALA A HB2  1 
ATOM   2497 H HB3  . ALA A 1 163 ? 9.99058   -17.88557 27.43480  1.000 17.14712  ? 177 ALA A HB3  1 
ATOM   2498 N N    . MET A 1 164 ? 7.41537   -17.49786 24.88657  1.000 11.67904  ? 178 MET A N    1 
ATOM   2499 C CA   . MET A 1 164 ? 6.80346   -18.36169 23.89485  1.000 11.26058  ? 178 MET A CA   1 
ATOM   2500 C C    . MET A 1 164 ? 7.78255   -18.47573 22.73896  1.000 10.99081  ? 178 MET A C    1 
ATOM   2501 O O    . MET A 1 164 ? 8.26717   -17.45414 22.23496  1.000 11.39247  ? 178 MET A O    1 
ATOM   2502 C CB   . MET A 1 164 ? 5.49178   -17.72887 23.43621  1.000 11.60071  ? 178 MET A CB   1 
ATOM   2503 C CG   . MET A 1 164 ? 4.75035   -18.48798 22.35891  1.000 12.77888  ? 178 MET A CG   1 
ATOM   2504 S SD   . MET A 1 164 ? 3.09893   -17.84413 22.09087  1.000 12.77390  ? 178 MET A SD   1 
ATOM   2505 C CE   . MET A 1 164 ? 2.23609   -18.56971 23.47192  1.000 13.45277  ? 178 MET A CE   1 
ATOM   2506 H H    . MET A 1 164 ? 7.63090   -16.72734 24.57122  1.000 14.00973  ? 178 MET A H    1 
ATOM   2507 H HA   . MET A 1 164 ? 6.61301   -19.24675 24.24312  1.000 13.50759  ? 178 MET A HA   1 
ATOM   2508 H HB2  . MET A 1 164 ? 4.90045   -17.66148 24.20217  1.000 13.91575  ? 178 MET A HB2  1 
ATOM   2509 H HB3  . MET A 1 164 ? 5.68444   -16.84465 23.08702  1.000 13.91575  ? 178 MET A HB3  1 
ATOM   2510 H HG2  . MET A 1 164 ? 5.24114   -18.41795 21.52517  1.000 15.32954  ? 178 MET A HG2  1 
ATOM   2511 H HG3  . MET A 1 164 ? 4.67309   -19.41864 22.62124  0.584 15.32954  ? 178 MET A HG3  1 
ATOM   2512 H HE1  . MET A 1 164 ? 1.34801   -18.18356 23.52762  0.707 16.13822  ? 178 MET A HE1  1 
ATOM   2513 H HE2  . MET A 1 164 ? 2.17218   -19.52803 23.33617  1.000 16.13822  ? 178 MET A HE2  1 
ATOM   2514 H HE3  . MET A 1 164 ? 2.72956   -18.38312 24.28591  1.000 16.13822  ? 178 MET A HE3  1 
ATOM   2515 N N    . SER A 1 165 ? 8.08258   -19.69938 22.31967  1.000 10.87748  ? 179 SER A N    1 
ATOM   2516 C CA   . SER A 1 165 ? 9.00689   -19.89317 21.21532  1.000 11.43966  ? 179 SER A CA   1 
ATOM   2517 C C    . SER A 1 165 ? 8.27916   -19.89976 19.88400  1.000 10.77048  ? 179 SER A C    1 
ATOM   2518 O O    . SER A 1 165 ? 7.15205   -20.39136 19.76501  1.000 11.32779  ? 179 SER A O    1 
ATOM   2519 C CB   . SER A 1 165 ? 9.80993   -21.17578 21.37007  1.000 12.63433  ? 179 SER A CB   1 
ATOM   2520 O OG   . SER A 1 165 ? 9.00067   -22.31892 21.23838  1.000 14.27793  ? 179 SER A OG   1 
ATOM   2521 H H    . SER A 1 165 ? 7.76592   -20.42453 22.65653  1.000 13.04787  ? 179 SER A H    1 
ATOM   2522 H HA   . SER A 1 165 ? 9.63023   -19.14997 21.21510  1.000 13.72249  ? 179 SER A HA   1 
ATOM   2523 H HB2  . SER A 1 165 ? 10.49590  -21.19876 20.68464  1.000 15.15608  ? 179 SER A HB2  1 
ATOM   2524 H HB3  . SER A 1 165 ? 10.21924  -21.18318 22.24945  1.000 15.15608  ? 179 SER A HB3  1 
ATOM   2525 H HG   . SER A 1 165 ? 9.46894   -23.01242 21.31166  1.000 17.12840  ? 179 SER A HG   1 
ATOM   2526 N N    . PHE A 1 166 ? 8.94952   -19.35339 18.87919  1.000 10.87420  ? 180 PHE A N    1 
ATOM   2527 C CA   . PHE A 1 166 ? 8.46833   -19.33328 17.50403  1.000 11.34763  ? 180 PHE A CA   1 
ATOM   2528 C C    . PHE A 1 166 ? 9.56220   -19.82192 16.57326  1.000 11.66972  ? 180 PHE A C    1 
ATOM   2529 O O    . PHE A 1 166 ? 10.74475  -19.51924 16.76437  1.000 12.19706  ? 180 PHE A O    1 
ATOM   2530 C CB   . PHE A 1 166 ? 8.08743   -17.90583 17.07644  1.000 12.45056  ? 180 PHE A CB   1 
ATOM   2531 C CG   . PHE A 1 166 ? 6.92941   -17.35790 17.83074  1.000 11.82012  ? 180 PHE A CG   1 
ATOM   2532 C CD1  . PHE A 1 166 ? 7.12434   -16.72276 19.05345  1.000 12.42768  ? 180 PHE A CD1  1 
ATOM   2533 C CD2  . PHE A 1 166 ? 5.64727   -17.46060 17.33577  1.000 12.87896  ? 180 PHE A CD2  1 
ATOM   2534 C CE1  . PHE A 1 166 ? 6.06233   -16.23726 19.77147  1.000 12.75156  ? 180 PHE A CE1  1 
ATOM   2535 C CE2  . PHE A 1 166 ? 4.58756   -16.98758 18.05321  1.000 12.96230  ? 180 PHE A CE2  1 
ATOM   2536 C CZ   . PHE A 1 166 ? 4.78525   -16.35966 19.26748  1.000 12.47875  ? 180 PHE A CZ   1 
ATOM   2537 H H    . PHE A 1 166 ? 9.71533   -18.97319 18.97179  1.000 13.04393  ? 180 PHE A H    1 
ATOM   2538 H HA   . PHE A 1 166 ? 7.69723   -19.91714 17.43046  1.000 13.61205  ? 180 PHE A HA   1 
ATOM   2539 H HB2  . PHE A 1 166 ? 8.84577   -17.32003 17.22693  1.000 14.93557  ? 180 PHE A HB2  1 
ATOM   2540 H HB3  . PHE A 1 166 ? 7.85446   -17.91169 16.13485  1.000 14.93557  ? 180 PHE A HB3  1 
ATOM   2541 H HD1  . PHE A 1 166 ? 7.98671   -16.62637 19.38799  1.000 14.90811  ? 180 PHE A HD1  1 
ATOM   2542 H HD2  . PHE A 1 166 ? 5.50329   -17.85546 16.50616  1.000 15.44964  ? 180 PHE A HD2  1 
ATOM   2543 H HE1  . PHE A 1 166 ? 6.20276   -15.82740 20.59440  1.000 15.29677  ? 180 PHE A HE1  1 
ATOM   2544 H HE2  . PHE A 1 166 ? 3.72455   -17.08881 17.72177  0.353 15.54966  ? 180 PHE A HE2  1 
ATOM   2545 H HZ   . PHE A 1 166 ? 4.06073   -16.02136 19.74238  1.000 14.96939  ? 180 PHE A HZ   1 
ATOM   2546 N N    . GLN A 1 167 ? 9.15486   -20.54258 15.54183  1.000 11.23989  ? 181 GLN A N    1 
ATOM   2547 C CA   . GLN A 1 167 ? 10.01875  -20.80796 14.40881  1.000 12.05896  ? 181 GLN A CA   1 
ATOM   2548 C C    . GLN A 1 167 ? 9.18954   -20.61975 13.15443  1.000 11.94280  ? 181 GLN A C    1 
ATOM   2549 O O    . GLN A 1 167 ? 8.09469   -21.17556 13.04319  1.000 13.31073  ? 181 GLN A O    1 
ATOM   2550 C CB   . GLN A 1 167 ? 10.63157  -22.20585 14.47498  1.000 13.80597  ? 181 GLN A CB   1 
ATOM   2551 C CG   . GLN A 1 167 ? 11.59468  -22.45420 13.34707  1.000 15.52344  ? 181 GLN A CG   1 
ATOM   2552 C CD   . GLN A 1 167 ? 12.46833  -23.66476 13.57851  1.000 18.23128  ? 181 GLN A CD   1 
ATOM   2553 O OE1  . GLN A 1 167 ? 12.99714  -23.87456 14.67126  1.000 20.22654  ? 181 GLN A OE1  1 
ATOM   2554 N NE2  . GLN A 1 167 ? 12.61999  -24.48033 12.55188  1.000 20.86009  ? 181 GLN A NE2  1 
ATOM   2555 H H    . GLN A 1 167 ? 8.37215   -20.89262 15.47533  1.000 13.48276  ? 181 GLN A H    1 
ATOM   2556 H HA   . GLN A 1 167 ? 10.76173  -20.18467 14.38915  1.000 14.46564  ? 181 GLN A HA   1 
ATOM   2557 H HB2  . GLN A 1 167 ? 11.11262  -22.30328 15.31163  1.000 16.56205  ? 181 GLN A HB2  1 
ATOM   2558 H HB3  . GLN A 1 167 ? 9.92363   -22.86671 14.42043  0.889 16.56205  ? 181 GLN A HB3  1 
ATOM   2559 H HG2  . GLN A 1 167 ? 11.09313  -22.59850 12.52944  1.000 18.62303  ? 181 GLN A HG2  1 
ATOM   2560 H HG3  . GLN A 1 167 ? 12.17294  -21.68154 13.24957  0.342 18.62303  ? 181 GLN A HG3  1 
ATOM   2561 H HE21 . GLN A 1 167 ? 12.23135  -24.30759 11.80440  1.000 25.02700  ? 181 GLN A HE21 1 
ATOM   2562 H HE22 . GLN A 1 167 ? 13.10745  -25.18447 12.63043  0.144 25.02700  ? 181 GLN A HE22 1 
ATOM   2563 N N    . ILE A 1 168 ? 9.71853   -19.82028 12.23896  1.000 12.06234  ? 182 ILE A N    1 
ATOM   2564 C CA   . ILE A 1 168 ? 9.12375   -19.58962 10.92660  1.000 12.07264  ? 182 ILE A CA   1 
ATOM   2565 C C    . ILE A 1 168 ? 10.06880  -20.20828 9.91738   1.000 12.58774  ? 182 ILE A C    1 
ATOM   2566 O O    . ILE A 1 168 ? 11.24362  -19.82774 9.87908   1.000 13.72514  ? 182 ILE A O    1 
ATOM   2567 C CB   . ILE A 1 168 ? 8.99497   -18.08712 10.64948  1.000 11.92204  ? 182 ILE A CB   1 
ATOM   2568 C CG1  . ILE A 1 168 ? 8.15879   -17.38841 11.72185  1.000 13.76437  ? 182 ILE A CG1  1 
ATOM   2569 C CG2  . ILE A 1 168 ? 8.41024   -17.85544 9.26438   1.000 14.11584  ? 182 ILE A CG2  1 
ATOM   2570 C CD1  . ILE A 1 168 ? 8.21686   -15.87642 11.61338  1.000 13.84124  ? 182 ILE A CD1  1 
ATOM   2571 H H    . ILE A 1 168 ? 10.44952  -19.38311 12.35784  1.000 14.46969  ? 182 ILE A H    1 
ATOM   2572 H HA   . ILE A 1 168 ? 8.25003   -20.00721 10.87057  0.852 14.48206  ? 182 ILE A HA   1 
ATOM   2573 H HB   . ILE A 1 168 ? 9.88431   -17.70112 10.68084  0.982 14.30134  ? 182 ILE A HB   1 
ATOM   2574 H HG12 . ILE A 1 168 ? 7.23270   -17.66145 11.62859  0.388 16.51214  ? 182 ILE A HG12 1 
ATOM   2575 H HG13 . ILE A 1 168 ? 8.49242   -17.64035 12.59713  1.000 16.51214  ? 182 ILE A HG13 1 
ATOM   2576 H HG21 . ILE A 1 168 ? 7.51498   -18.22752 9.23325   0.785 16.93390  ? 182 ILE A HG21 1 
ATOM   2577 H HG22 . ILE A 1 168 ? 8.37829   -16.90168 9.09057   0.822 16.93390  ? 182 ILE A HG22 1 
ATOM   2578 H HG23 . ILE A 1 168 ? 8.97329   -18.29284 8.60669   1.000 16.93390  ? 182 ILE A HG23 1 
ATOM   2579 H HD11 . ILE A 1 168 ? 9.14539   -15.59608 11.60167  1.000 16.60438  ? 182 ILE A HD11 1 
ATOM   2580 H HD12 . ILE A 1 168 ? 7.77798   -15.60156 10.79318  1.000 16.60438  ? 182 ILE A HD12 1 
ATOM   2581 H HD13 . ILE A 1 168 ? 7.76347   -15.48734 12.37755  1.000 16.60438  ? 182 ILE A HD13 1 
ATOM   2582 N N    . ASP A 1 169 ? 9.57678   -21.15039 9.11216   1.000 12.50049  ? 183 ASP A N    1 
ATOM   2583 C CA   . ASP A 1 169 ? 10.37321  -21.79034 8.06937   1.000 13.51455  ? 183 ASP A CA   1 
ATOM   2584 C C    . ASP A 1 169 ? 9.68614   -21.57583 6.73224   1.000 13.72921  ? 183 ASP A C    1 
ATOM   2585 O O    . ASP A 1 169 ? 8.49584   -21.87656 6.59525   1.000 14.31806  ? 183 ASP A O    1 
ATOM   2586 C CB   . ASP A 1 169 ? 10.47615  -23.30449 8.28566   1.000 15.84055  ? 183 ASP A CB   1 
ATOM   2587 C CG   . ASP A 1 169 ? 11.23855  -23.66614 9.51909   1.000 18.19625  ? 183 ASP A CG   1 
ATOM   2588 O OD1  . ASP A 1 169 ? 12.43720  -23.33702 9.59198   1.000 20.42264  ? 183 ASP A OD1  1 
ATOM   2589 O OD2  . ASP A 1 169 ? 10.63556  -24.27902 10.42192  1.000 18.81605  ? 183 ASP A OD2  1 
ATOM   2590 H H    . ASP A 1 169 ? 8.76800   -21.43986 9.15315   1.000 14.99548  ? 183 ASP A H    1 
ATOM   2591 H HA   . ASP A 1 169 ? 11.25946  -21.39607 8.07350   1.000 16.21235  ? 183 ASP A HA   1 
ATOM   2592 H HB2  . ASP A 1 169 ? 9.58256   -23.67287 8.36750   0.763 19.00355  ? 183 ASP A HB2  1 
ATOM   2593 H HB3  . ASP A 1 169 ? 10.93035  -23.70144 7.52603   0.370 19.00355  ? 183 ASP A HB3  1 
ATOM   2594 N N    . VAL A 1 170 ? 10.44530  -21.11297 5.73874   1.000 13.77011  ? 184 VAL A N    1 
ATOM   2595 C CA   . VAL A 1 170 ? 9.98856   -21.00460 4.35786   1.000 14.67110  ? 184 VAL A CA   1 
ATOM   2596 C C    . VAL A 1 170 ? 10.90659  -21.86566 3.51352   1.000 15.14859  ? 184 VAL A C    1 
ATOM   2597 O O    . VAL A 1 170 ? 12.12927  -21.68331 3.53091   1.000 16.66301  ? 184 VAL A O    1 
ATOM   2598 C CB   . VAL A 1 170 ? 10.01323  -19.55705 3.85806   1.000 15.89206  ? 184 VAL A CB   1 
ATOM   2599 C CG1  . VAL A 1 170 ? 9.64683   -19.50146 2.38512   1.000 16.93771  ? 184 VAL A CG1  1 
ATOM   2600 C CG2  . VAL A 1 170 ? 9.07100   -18.70322 4.68488   1.000 17.09862  ? 184 VAL A CG2  1 
ATOM   2601 H H    . VAL A 1 170 ? 11.25606  -20.84717 5.84653   1.000 16.51902  ? 184 VAL A H    1 
ATOM   2602 H HA   . VAL A 1 170 ? 9.08028   -21.33837 4.29048   1.000 17.60021  ? 184 VAL A HA   1 
ATOM   2603 H HB   . VAL A 1 170 ? 10.90905  -19.19815 3.95602   1.000 19.06537  ? 184 VAL A HB   1 
ATOM   2604 H HG11 . VAL A 1 170 ? 9.46976   -18.58025 2.13829   0.006 20.32015  ? 184 VAL A HG11 1 
ATOM   2605 H HG12 . VAL A 1 170 ? 10.38695  -19.84758 1.86231   0.326 20.32015  ? 184 VAL A HG12 1 
ATOM   2606 H HG13 . VAL A 1 170 ? 8.85524   -20.04187 2.23599   1.000 20.32015  ? 184 VAL A HG13 1 
ATOM   2607 H HG21 . VAL A 1 170 ? 8.50255   -19.28321 5.21533   1.000 20.51323  ? 184 VAL A HG21 1 
ATOM   2608 H HG22 . VAL A 1 170 ? 9.59337   -18.12954 5.26706   0.343 20.51323  ? 184 VAL A HG22 1 
ATOM   2609 H HG23 . VAL A 1 170 ? 8.52853   -18.16356 4.08873   1.000 20.51323  ? 184 VAL A HG23 1 
ATOM   2610 N N    . LYS A 1 171 ? 10.32588  -22.80461 2.78022   1.000 17.25968  ? 185 LYS A N    1 
ATOM   2611 C CA   A LYS A 1 171 ? 11.09854  -23.67715 1.91070   0.028 18.94678  ? 185 LYS A CA   1 
ATOM   2612 C CA   B LYS A 1 171 ? 11.09827  -23.67598 1.90849   0.972 19.89818  ? 185 LYS A CA   1 
ATOM   2613 C C    . LYS A 1 171 ? 10.20035  -24.10426 0.76441   1.000 19.91856  ? 185 LYS A C    1 
ATOM   2614 O O    . LYS A 1 171 ? 9.07276   -24.54553 0.99595   1.000 19.11041  ? 185 LYS A O    1 
ATOM   2615 C CB   A LYS A 1 171 ? 11.58736  -24.91091 2.67766   0.028 19.66495  ? 185 LYS A CB   1 
ATOM   2616 C CB   B LYS A 1 171 ? 11.57779  -24.91212 2.67163   0.972 22.52974  ? 185 LYS A CB   1 
ATOM   2617 C CG   A LYS A 1 171 ? 12.46788  -25.84770 1.86299   0.028 20.37624  ? 185 LYS A CG   1 
ATOM   2618 C CG   B LYS A 1 171 ? 12.49549  -25.82894 1.87024   0.972 27.20761  ? 185 LYS A CG   1 
ATOM   2619 C CD   A LYS A 1 171 ? 12.76149  -27.13084 2.62424   0.028 20.96491  ? 185 LYS A CD   1 
ATOM   2620 C CD   B LYS A 1 171 ? 12.78484  -27.12477 2.61134   0.972 31.27826  ? 185 LYS A CD   1 
ATOM   2621 C CE   A LYS A 1 171 ? 13.58953  -28.09879 1.79377   0.028 21.42649  ? 185 LYS A CE   1 
ATOM   2622 C CE   B LYS A 1 171 ? 13.81669  -27.97519 1.87082   0.972 34.91165  ? 185 LYS A CE   1 
ATOM   2623 N NZ   A LYS A 1 171 ? 14.90820  -27.52520 1.40753   0.028 21.62826  ? 185 LYS A NZ   1 
ATOM   2624 N NZ   B LYS A 1 171 ? 14.00383  -29.33848 2.47279   0.972 36.71994  ? 185 LYS A NZ   1 
ATOM   2625 H H    . LYS A 1 171 ? 9.47966   -22.95766 2.77027   1.000 20.70651  ? 185 LYS A H    1 
ATOM   2626 H HA   . LYS A 1 171 ? 11.86889  -23.20592 1.55657   1.000 23.87270  ? 185 LYS A HA   1 
ATOM   2627 H HB2  A LYS A 1 171 ? 12.10352  -24.61477 3.44367   0.028 23.59283  ? 185 LYS A HB2  1 
ATOM   2628 H HB2  B LYS A 1 171 ? 12.06694  -24.62060 3.45690   0.972 27.03058  ? 185 LYS A HB2  1 
ATOM   2629 H HB3  A LYS A 1 171 ? 10.81492  -25.41738 2.97384   0.028 23.59283  ? 185 LYS A HB3  1 
ATOM   2630 H HB3  B LYS A 1 171 ? 10.80295  -25.43167 2.93735   0.972 27.03058  ? 185 LYS A HB3  1 
ATOM   2631 H HG2  A LYS A 1 171 ? 12.01453  -26.07903 1.03724   0.028 24.44638  ? 185 LYS A HG2  1 
ATOM   2632 H HG2  B LYS A 1 171 ? 12.07043  -26.04983 1.02677   0.972 32.64402  ? 185 LYS A HG2  1 
ATOM   2633 H HG3  A LYS A 1 171 ? 13.31043  -25.40878 1.66717   0.028 24.44638  ? 185 LYS A HG3  1 
ATOM   2634 H HG3  B LYS A 1 171 ? 13.33829  -25.37676 1.70862   0.972 32.64402  ? 185 LYS A HG3  1 
ATOM   2635 H HD2  A LYS A 1 171 ? 13.25833  -26.91921 3.43001   0.028 25.15278  ? 185 LYS A HD2  1 
ATOM   2636 H HD2  B LYS A 1 171 ? 13.13465  -26.91973 3.49253   0.972 37.52881  ? 185 LYS A HD2  1 
ATOM   2637 H HD3  A LYS A 1 171 ? 11.92552  -27.56561 2.85451   0.028 25.15278  ? 185 LYS A HD3  1 
ATOM   2638 H HD3  B LYS A 1 171 ? 11.96631  -27.63916 2.69077   0.972 37.52881  ? 185 LYS A HD3  1 
ATOM   2639 H HE2  A LYS A 1 171 ? 13.75021  -28.90416 2.30997   0.028 25.70668  ? 185 LYS A HE2  1 
ATOM   2640 H HE2  B LYS A 1 171 ? 13.52669  -28.09258 0.95266   0.972 41.88887  ? 185 LYS A HE2  1 
ATOM   2641 H HE3  A LYS A 1 171 ? 13.10544  -28.31622 0.98181   0.028 25.70668  ? 185 LYS A HE3  1 
ATOM   2642 H HE3  B LYS A 1 171 ? 14.67306  -27.52016 1.89265   0.972 41.88887  ? 185 LYS A HE3  1 
ATOM   2643 H HZ1  A LYS A 1 171 ? 15.26096  -27.08322 2.09478   0.028 25.94880  ? 185 LYS A HZ1  1 
ATOM   2644 H HZ1  B LYS A 1 171 ? 13.22361  -29.76519 2.50849   0.972 44.05882  ? 185 LYS A HZ1  1 
ATOM   2645 H HZ2  A LYS A 1 171 ? 15.46476  -28.17664 1.16676   0.028 25.94880  ? 185 LYS A HZ2  1 
ATOM   2646 H HZ2  B LYS A 1 171 ? 14.57087  -29.81422 1.97859   0.972 44.05882  ? 185 LYS A HZ2  1 
ATOM   2647 H HZ3  A LYS A 1 171 ? 14.80762  -26.96395 0.72417   0.028 25.94880  ? 185 LYS A HZ3  1 
ATOM   2648 H HZ3  B LYS A 1 171 ? 14.33079  -29.26491 3.29728   0.972 44.05882  ? 185 LYS A HZ3  1 
ATOM   2649 N N    . ASP A 1 172 ? 10.69723  -23.95996 -0.45866  1.000 20.82016  ? 186 ASP A N    1 
ATOM   2650 C CA   . ASP A 1 172 ? 10.00458  -24.47076 -1.63221  1.000 21.88536  ? 186 ASP A CA   1 
ATOM   2651 C C    . ASP A 1 172 ? 8.54889   -24.00892 -1.65026  1.000 20.74756  ? 186 ASP A C    1 
ATOM   2652 O O    . ASP A 1 172 ? 7.61341   -24.78970 -1.84888  1.000 21.08941  ? 186 ASP A O    1 
ATOM   2653 C CB   . ASP A 1 172 ? 10.11916  -25.99416 -1.70367  1.000 24.35214  ? 186 ASP A CB   1 
ATOM   2654 C CG   . ASP A 1 172 ? 11.55223  -26.46348 -1.90148  1.000 28.53818  ? 186 ASP A CG   1 
ATOM   2655 O OD1  . ASP A 1 172 ? 12.33777  -25.73086 -2.54529  1.000 29.74917  ? 186 ASP A OD1  1 
ATOM   2656 O OD2  . ASP A 1 172 ? 11.89054  -27.56423 -1.41455  1.000 30.68156  ? 186 ASP A OD2  1 
ATOM   2657 H H    . ASP A 1 172 ? 11.44106  -23.56594 -0.63491  0.746 24.97909  ? 186 ASP A H    1 
ATOM   2658 H HA   . ASP A 1 172 ? 10.42511  -24.10791 -2.42744  0.118 26.25732  ? 186 ASP A HA   1 
ATOM   2659 H HB2  . ASP A 1 172 ? 9.78945   -26.37583 -0.87511  1.000 29.21746  ? 186 ASP A HB2  1 
ATOM   2660 H HB3  . ASP A 1 172 ? 9.59128   -26.31682 -2.45075  1.000 29.21746  ? 186 ASP A HB3  1 
ATOM   2661 N N    . SER A 1 173 ? 8.36093   -22.71264 -1.42864  1.000 19.35676  ? 187 SER A N    1 
ATOM   2662 C CA   . SER A 1 173 ? 7.06618   -22.05741 -1.56983  1.000 18.90568  ? 187 SER A CA   1 
ATOM   2663 C C    . SER A 1 173 ? 6.06357   -22.50461 -0.51726  1.000 17.38753  ? 187 SER A C    1 
ATOM   2664 O O    . SER A 1 173 ? 4.85046   -22.42607 -0.75278  1.000 18.49102  ? 187 SER A O    1 
ATOM   2665 C CB   . SER A 1 173 ? 6.47867   -22.24465 -2.97813  1.000 20.25593  ? 187 SER A CB   1 
ATOM   2666 O OG   . SER A 1 173 ? 7.38419   -21.79005 -3.96679  1.000 21.43770  ? 187 SER A OG   1 
ATOM   2667 H H    . SER A 1 173 ? 8.98858   -22.17621 -1.18805  1.000 23.22300  ? 187 SER A H    1 
ATOM   2668 H HA   . SER A 1 173 ? 7.20629   -21.10621 -1.44145  1.000 22.68170  ? 187 SER A HA   1 
ATOM   2669 H HB2  . SER A 1 173 ? 6.30014   -23.18701 -3.12296  1.000 24.30201  ? 187 SER A HB2  1 
ATOM   2670 H HB3  . SER A 1 173 ? 5.65520   -21.73661 -3.04675  0.718 24.30201  ? 187 SER A HB3  1 
ATOM   2671 H HG   . SER A 1 173 ? 7.55125   -20.97509 -3.85042  0.396 25.72013  ? 187 SER A HG   1 
ATOM   2672 N N    . LYS A 1 174 ? 6.54201   -23.00024 0.61923   1.000 16.48935  ? 188 LYS A N    1 
ATOM   2673 C CA   . LYS A 1 174 ? 5.68067   -23.39419 1.72167   1.000 17.05588  ? 188 LYS A CA   1 
ATOM   2674 C C    . LYS A 1 174 ? 6.16834   -22.77084 3.02014   1.000 15.03439  ? 188 LYS A C    1 
ATOM   2675 O O    . LYS A 1 174 ? 7.36569   -22.57129 3.22582   1.000 16.13102  ? 188 LYS A O    1 
ATOM   2676 C CB   . LYS A 1 174 ? 5.62626   -24.90420 1.87514   1.000 20.59502  ? 188 LYS A CB   1 
ATOM   2677 C CG   . LYS A 1 174 ? 5.09415   -25.57113 0.63197   1.000 24.44353  ? 188 LYS A CG   1 
ATOM   2678 C CD   . LYS A 1 174 ? 4.40850   -26.88031 0.92762   1.000 28.45393  ? 188 LYS A CD   1 
ATOM   2679 C CE   . LYS A 1 174 ? 3.87321   -27.51134 -0.35213  1.000 32.09788  ? 188 LYS A CE   1 
ATOM   2680 N NZ   . LYS A 1 174 ? 3.04715   -26.57186 -1.17619  1.000 34.21607  ? 188 LYS A NZ   1 
ATOM   2681 H H    . LYS A 1 174 ? 7.37919   -23.11912 0.77601   0.910 19.78211  ? 188 LYS A H    1 
ATOM   2682 H HA   . LYS A 1 174 ? 4.78336   -23.06768 1.55104   1.000 20.46194  ? 188 LYS A HA   1 
ATOM   2683 H HB2  . LYS A 1 174 ? 6.52024   -25.24106 2.04315   1.000 24.70892  ? 188 LYS A HB2  1 
ATOM   2684 H HB3  . LYS A 1 174 ? 5.04212   -25.12958 2.61601   1.000 24.70892  ? 188 LYS A HB3  1 
ATOM   2685 H HG2  . LYS A 1 174 ? 4.44961   -24.98344 0.20760   1.000 29.32713  ? 188 LYS A HG2  1 
ATOM   2686 H HG3  . LYS A 1 174 ? 5.83101   -25.74783 0.02640   1.000 29.32713  ? 188 LYS A HG3  1 
ATOM   2687 H HD2  . LYS A 1 174 ? 5.04187   -27.49378 1.33184   1.000 34.13961  ? 188 LYS A HD2  1 
ATOM   2688 H HD3  . LYS A 1 174 ? 3.66397   -26.72734 1.53026   1.000 34.13961  ? 188 LYS A HD3  1 
ATOM   2689 H HE2  . LYS A 1 174 ? 4.62188   -27.80352 -0.89528  0.014 38.51235  ? 188 LYS A HE2  1 
ATOM   2690 H HE3  . LYS A 1 174 ? 3.31629   -28.27051 -0.11891  1.000 38.51235  ? 188 LYS A HE3  1 
ATOM   2691 H HZ1  . LYS A 1 174 ? 2.65412   -27.01484 -1.84057  0.010 41.05418  ? 188 LYS A HZ1  1 
ATOM   2692 H HZ2  . LYS A 1 174 ? 2.42001   -26.19406 -0.67017  1.000 41.05418  ? 188 LYS A HZ2  1 
ATOM   2693 H HZ3  . LYS A 1 174 ? 3.56376   -25.93399 -1.52019  1.000 41.05418  ? 188 LYS A HZ3  1 
ATOM   2694 N N    . LEU A 1 175 ? 5.22148   -22.50491 3.90898   1.000 13.66654  ? 189 LEU A N    1 
ATOM   2695 C CA   . LEU A 1 175 ? 5.47200   -21.84836 5.18138   1.000 13.06826  ? 189 LEU A CA   1 
ATOM   2696 C C    . LEU A 1 175 ? 5.06009   -22.76717 6.31509   1.000 12.44944  ? 189 LEU A C    1 
ATOM   2697 O O    . LEU A 1 175 ? 3.94682   -23.29646 6.30458   1.000 13.15202  ? 189 LEU A O    1 
ATOM   2698 C CB   . LEU A 1 175 ? 4.62005   -20.59129 5.24806   1.000 13.27466  ? 189 LEU A CB   1 
ATOM   2699 C CG   . LEU A 1 175 ? 4.51409   -19.91152 6.61679   1.000 12.80665  ? 189 LEU A CG   1 
ATOM   2700 C CD1  . LEU A 1 175 ? 5.83505   -19.32085 7.05198   1.000 13.43123  ? 189 LEU A CD1  1 
ATOM   2701 C CD2  . LEU A 1 175 ? 3.43178   -18.84518 6.56645   1.000 14.35700  ? 189 LEU A CD2  1 
ATOM   2702 H H    . LEU A 1 175 ? 4.39303   -22.70374 3.79176   0.803 16.39473  ? 189 LEU A H    1 
ATOM   2703 H HA   . LEU A 1 175 ? 6.41493   -21.64225 5.27776   1.000 15.67680  ? 189 LEU A HA   1 
ATOM   2704 H HB2  . LEU A 1 175 ? 4.99562   -19.94056 4.63455   1.000 15.92448  ? 189 LEU A HB2  1 
ATOM   2705 H HB3  . LEU A 1 175 ? 3.71898   -20.82380 4.97437   1.000 15.92448  ? 189 LEU A HB3  1 
ATOM   2706 H HG   . LEU A 1 175 ? 4.27517   -20.57444 7.28340   1.000 15.36288  ? 189 LEU A HG   1 
ATOM   2707 H HD11 . LEU A 1 175 ? 5.73988   -18.95973 7.94721   0.914 16.11237  ? 189 LEU A HD11 1 
ATOM   2708 H HD12 . LEU A 1 175 ? 6.50974   -20.01775 7.04641   1.000 16.11237  ? 189 LEU A HD12 1 
ATOM   2709 H HD13 . LEU A 1 175 ? 6.08375   -18.61474 6.43517   1.000 16.11237  ? 189 LEU A HD13 1 
ATOM   2710 H HD21 . LEU A 1 175 ? 3.29658   -18.49006 7.45892   1.000 17.22329  ? 189 LEU A HD21 1 
ATOM   2711 H HD22 . LEU A 1 175 ? 3.71447   -18.13631 5.96770   0.574 17.22329  ? 189 LEU A HD22 1 
ATOM   2712 H HD23 . LEU A 1 175 ? 2.60979   -19.24460 6.24134   0.551 17.22329  ? 189 LEU A HD23 1 
ATOM   2713 N N    . THR A 1 176 ? 5.93945   -22.92649 7.29821   1.000 12.35824  ? 190 THR A N    1 
ATOM   2714 C CA   . THR A 1 176 ? 5.59760   -23.60099 8.53887   1.000 12.86156  ? 190 THR A CA   1 
ATOM   2715 C C    . THR A 1 176 ? 5.88622   -22.67414 9.70692   1.000 11.83273  ? 190 THR A C    1 
ATOM   2716 O O    . THR A 1 176 ? 6.92401   -22.00588 9.74438   1.000 13.22991  ? 190 THR A O    1 
ATOM   2717 C CB   . THR A 1 176 ? 6.37115   -24.90685 8.66631   1.000 14.58458  ? 190 THR A CB   1 
ATOM   2718 O OG1  . THR A 1 176 ? 5.94966   -25.75800 7.59820   1.000 16.55352  ? 190 THR A OG1  1 
ATOM   2719 C CG2  . THR A 1 176 ? 6.09391   -25.61718 9.99334   1.000 15.77396  ? 190 THR A CG2  1 
ATOM   2720 H H    . THR A 1 176 ? 6.75215   -22.64702 7.26649   1.000 14.82478  ? 190 THR A H    1 
ATOM   2721 H HA   . THR A 1 176 ? 4.65203   -23.81579 8.56438   1.000 15.42877  ? 190 THR A HA   1 
ATOM   2722 H HB   . THR A 1 176 ? 7.32345   -24.72526 8.63392   1.000 17.49639  ? 190 THR A HB   1 
ATOM   2723 H HG1  . THR A 1 176 ? 5.19521   -26.08420 7.77141   1.000 19.85911  ? 190 THR A HG1  1 
ATOM   2724 H HG21 . THR A 1 176 ? 6.47742   -26.50803 9.97924   1.000 18.92364  ? 190 THR A HG21 1 
ATOM   2725 H HG22 . THR A 1 176 ? 6.48661   -25.11695 10.72578  0.322 18.92364  ? 190 THR A HG22 1 
ATOM   2726 H HG23 . THR A 1 176 ? 5.13740   -25.68847 10.13797  1.000 18.92364  ? 190 THR A HG23 1 
ATOM   2727 N N    . ILE A 1 177 ? 4.95458   -22.62666 10.65352  1.000 11.09431  ? 191 ILE A N    1 
ATOM   2728 C CA   . ILE A 1 177 ? 5.12886   -21.89128 11.89722  1.000 10.92615  ? 191 ILE A CA   1 
ATOM   2729 C C    . ILE A 1 177 ? 4.97169   -22.88125 13.03830  1.000 11.53861  ? 191 ILE A C    1 
ATOM   2730 O O    . ILE A 1 177 ? 3.95211   -23.57555 13.13195  1.000 11.61865  ? 191 ILE A O    1 
ATOM   2731 C CB   . ILE A 1 177 ? 4.12859   -20.73233 12.05165  1.000 11.29599  ? 191 ILE A CB   1 
ATOM   2732 C CG1  . ILE A 1 177 ? 4.19361   -19.77663 10.85485  1.000 12.05290  ? 191 ILE A CG1  1 
ATOM   2733 C CG2  . ILE A 1 177 ? 4.41514   -20.00626 13.36268  1.000 12.44628  ? 191 ILE A CG2  1 
ATOM   2734 C CD1  . ILE A 1 177 ? 3.12378   -18.68840 10.87172  1.000 13.10861  ? 191 ILE A CD1  1 
ATOM   2735 H H    . ILE A 1 177 ? 4.19398   -23.02365 10.59452  1.000 13.30807  ? 191 ILE A H    1 
ATOM   2736 H HA   . ILE A 1 177 ? 6.02119   -21.51136 11.91485  1.000 13.10627  ? 191 ILE A HA   1 
ATOM   2737 H HB   . ILE A 1 177 ? 3.22709   -21.08975 12.07275  1.000 13.55008  ? 191 ILE A HB   1 
ATOM   2738 H HG12 . ILE A 1 177 ? 5.05944   -19.33933 10.85264  0.567 14.45837  ? 191 ILE A HG12 1 
ATOM   2739 H HG13 . ILE A 1 177 ? 4.07930   -20.29031 10.04000  1.000 14.45837  ? 191 ILE A HG13 1 
ATOM   2740 H HG21 . ILE A 1 177 ? 5.35079   -19.75134 13.38453  0.610 14.93043  ? 191 ILE A HG21 1 
ATOM   2741 H HG22 . ILE A 1 177 ? 3.85560   -19.21563 13.41466  1.000 14.93043  ? 191 ILE A HG22 1 
ATOM   2742 H HG23 . ILE A 1 177 ? 4.21697   -20.60099 14.10290  0.552 14.93043  ? 191 ILE A HG23 1 
ATOM   2743 H HD11 . ILE A 1 177 ? 2.25009   -19.10539 10.93246  1.000 15.72522  ? 191 ILE A HD11 1 
ATOM   2744 H HD12 . ILE A 1 177 ? 3.27006   -18.11362 11.63927  1.000 15.72522  ? 191 ILE A HD12 1 
ATOM   2745 H HD13 . ILE A 1 177 ? 3.18706   -18.17064 10.05391  1.000 15.72522  ? 191 ILE A HD13 1 
ATOM   2746 N N    . THR A 1 178 ? 5.97109   -22.91900 13.91139  1.000 11.09386  ? 192 THR A N    1 
ATOM   2747 C CA   . THR A 1 178 ? 5.98487   -23.75964 15.09425  1.000 11.15639  ? 192 THR A CA   1 
ATOM   2748 C C    . THR A 1 178 ? 5.97317   -22.84561 16.31188  1.000 11.53534  ? 192 THR A C    1 
ATOM   2749 O O    . THR A 1 178 ? 6.80688   -21.93800 16.41942  1.000 12.38802  ? 192 THR A O    1 
ATOM   2750 C CB   . THR A 1 178 ? 7.25181   -24.62000 15.08375  1.000 11.90195  ? 192 THR A CB   1 
ATOM   2751 O OG1  . THR A 1 178 ? 7.33640   -25.34718 13.85045  1.000 13.21328  ? 192 THR A OG1  1 
ATOM   2752 C CG2  . THR A 1 178 ? 7.24263   -25.61931 16.20245  1.000 12.85131  ? 192 THR A CG2  1 
ATOM   2753 H H    . THR A 1 178 ? 6.68341   -22.44348 13.83349  1.000 13.30752  ? 192 THR A H    1 
ATOM   2754 H HA   . THR A 1 178 ? 5.21013   -24.34204 15.13278  1.000 13.38256  ? 192 THR A HA   1 
ATOM   2755 H HB   . THR A 1 178 ? 8.01742   -24.03379 15.18905  1.000 14.27724  ? 192 THR A HB   1 
ATOM   2756 H HG1  . THR A 1 178 ? 6.66833   -25.84943 13.76666  0.428 15.85083  ? 192 THR A HG1  1 
ATOM   2757 H HG21 . THR A 1 178 ? 8.08280   -26.10371 16.22150  1.000 15.41647  ? 192 THR A HG21 1 
ATOM   2758 H HG22 . THR A 1 178 ? 7.12135   -25.16589 17.05133  1.000 15.41647  ? 192 THR A HG22 1 
ATOM   2759 H HG23 . THR A 1 178 ? 6.51763   -26.25135 16.07676  0.980 15.41647  ? 192 THR A HG23 1 
ATOM   2760 N N    . VAL A 1 179 ? 5.05195   -23.09996 17.23498  1.000 10.90454  ? 193 VAL A N    1 
ATOM   2761 C CA   . VAL A 1 179 ? 4.87267   -22.28531 18.43324  1.000 11.54867  ? 193 VAL A CA   1 
ATOM   2762 C C    . VAL A 1 179 ? 5.02168   -23.20720 19.63297  1.000 11.39452  ? 193 VAL A C    1 
ATOM   2763 O O    . VAL A 1 179 ? 4.32132   -24.21997 19.74068  1.000 11.65389  ? 193 VAL A O    1 
ATOM   2764 C CB   . VAL A 1 179 ? 3.52421   -21.55068 18.44484  1.000 12.93010  ? 193 VAL A CB   1 
ATOM   2765 C CG1  . VAL A 1 179 ? 3.29456   -20.85152 19.76655  1.000 14.46323  ? 193 VAL A CG1  1 
ATOM   2766 C CG2  . VAL A 1 179 ? 3.50872   -20.52440 17.34324  1.000 15.52029  ? 193 VAL A CG2  1 
ATOM   2767 H H    . VAL A 1 179 ? 4.50178   -23.75929 17.18813  1.000 13.08034  ? 193 VAL A H    1 
ATOM   2768 H HA   . VAL A 1 179 ? 5.56818   -21.61055 18.47622  0.856 13.85329  ? 193 VAL A HA   1 
ATOM   2769 H HB   . VAL A 1 179 ? 2.81595   -22.20019 18.31295  1.000 15.51101  ? 193 VAL A HB   1 
ATOM   2770 H HG11 . VAL A 1 179 ? 3.18532   -21.51883 20.46201  1.000 17.35077  ? 193 VAL A HG11 1 
ATOM   2771 H HG12 . VAL A 1 179 ? 4.06053   -20.29015 19.96414  1.000 17.35077  ? 193 VAL A HG12 1 
ATOM   2772 H HG13 . VAL A 1 179 ? 2.49398   -20.30772 19.70124  0.550 17.35077  ? 193 VAL A HG13 1 
ATOM   2773 H HG21 . VAL A 1 179 ? 4.35602   -20.05219 17.33962  1.000 18.61924  ? 193 VAL A HG21 1 
ATOM   2774 H HG22 . VAL A 1 179 ? 3.37726   -20.97451 16.49412  1.000 18.61924  ? 193 VAL A HG22 1 
ATOM   2775 H HG23 . VAL A 1 179 ? 2.78314   -19.90073 17.50284  1.000 18.61924  ? 193 VAL A HG23 1 
ATOM   2776 N N    . ASN A 1 180 ? 5.95176   -22.87041 20.52129  1.000 11.39886  ? 194 ASN A N    1 
ATOM   2777 C CA   . ASN A 1 180 ? 6.22582   -23.70819 21.67814  1.000 12.57191  ? 194 ASN A CA   1 
ATOM   2778 C C    . ASN A 1 180 ? 6.42361   -25.15707 21.26806  1.000 12.02982  ? 194 ASN A C    1 
ATOM   2779 O O    . ASN A 1 180 ? 5.96784   -26.08467 21.93871  1.000 13.28961  ? 194 ASN A O    1 
ATOM   2780 C CB   . ASN A 1 180 ? 5.15803   -23.56064 22.76364  1.000 13.45535  ? 194 ASN A CB   1 
ATOM   2781 C CG   . ASN A 1 180 ? 5.31415   -22.28364 23.54450  1.000 13.11210  ? 194 ASN A CG   1 
ATOM   2782 O OD1  . ASN A 1 180 ? 6.38647   -21.70112 23.58229  1.000 13.61108  ? 194 ASN A OD1  1 
ATOM   2783 N ND2  . ASN A 1 180 ? 4.25751   -21.84974 24.19221  1.000 14.42517  ? 194 ASN A ND2  1 
ATOM   2784 H H    . ASN A 1 180 ? 6.43606   -22.16131 20.47400  1.000 13.67352  ? 194 ASN A H    1 
ATOM   2785 H HA   . ASN A 1 180 ? 7.05859   -23.40659 22.07366  0.665 15.08119  ? 194 ASN A HA   1 
ATOM   2786 H HB2  . ASN A 1 180 ? 4.28113   -23.55622 22.34901  1.000 16.14131  ? 194 ASN A HB2  1 
ATOM   2787 H HB3  . ASN A 1 180 ? 5.22857   -24.30411 23.38265  0.814 16.14131  ? 194 ASN A HB3  1 
ATOM   2788 H HD21 . ASN A 1 180 ? 3.52044   -22.29147 24.15748  1.000 17.30509  ? 194 ASN A HD21 1 
ATOM   2789 H HD22 . ASN A 1 180 ? 4.30255   -21.12383 24.65116  1.000 17.30509  ? 194 ASN A HD22 1 
ATOM   2790 N N    . GLY A 1 181 ? 7.14255   -25.34169 20.16723  1.000 12.33662  ? 195 GLY A N    1 
ATOM   2791 C CA   . GLY A 1 181 ? 7.54212   -26.64906 19.69941  1.000 12.72755  ? 195 GLY A CA   1 
ATOM   2792 C C    . GLY A 1 181 ? 6.51999   -27.39869 18.87467  1.000 12.89940  ? 195 GLY A C    1 
ATOM   2793 O O    . GLY A 1 181 ? 6.85604   -28.44267 18.32608  1.000 13.75092  ? 195 GLY A O    1 
ATOM   2794 H H    . GLY A 1 181 ? 7.41673   -24.70165 19.66249  1.000 14.79883  ? 195 GLY A H    1 
ATOM   2795 H HA2  . GLY A 1 181 ? 8.33860   -26.54900 19.15488  1.000 15.26796  ? 195 GLY A HA2  1 
ATOM   2796 H HA3  . GLY A 1 181 ? 7.75357   -27.19851 20.47030  1.000 15.26796  ? 195 GLY A HA3  1 
ATOM   2797 N N    . ASN A 1 182 ? 5.29798   -26.89664 18.74101  1.000 12.27913  ? 196 ASN A N    1 
ATOM   2798 C CA   . ASN A 1 182 ? 4.23064   -27.58377 18.02205  1.000 12.90001  ? 196 ASN A CA   1 
ATOM   2799 C C    . ASN A 1 182 ? 3.87045   -26.81101 16.76162  1.000 12.54960  ? 196 ASN A C    1 
ATOM   2800 O O    . ASN A 1 182 ? 3.69705   -25.59387 16.80712  1.000 12.02608  ? 196 ASN A O    1 
ATOM   2801 C CB   . ASN A 1 182 ? 3.00490   -27.72527 18.92287  1.000 13.46938  ? 196 ASN A CB   1 
ATOM   2802 C CG   . ASN A 1 182 ? 1.87835   -28.52037 18.27569  1.000 14.45581  ? 196 ASN A CG   1 
ATOM   2803 O OD1  . ASN A 1 182 ? 2.09822   -29.55777 17.66013  1.000 13.98524  ? 196 ASN A OD1  1 
ATOM   2804 N ND2  . ASN A 1 182 ? 0.65378   -28.01743 18.41568  1.000 18.64691  ? 196 ASN A ND2  1 
ATOM   2805 H H    . ASN A 1 182 ? 5.05605   -26.13848 19.06698  1.000 14.72985  ? 196 ASN A H    1 
ATOM   2806 H HA   . ASN A 1 182 ? 4.53150   -28.46484 17.74985  1.000 15.47490  ? 196 ASN A HA   1 
ATOM   2807 H HB2  . ASN A 1 182 ? 3.26398   -28.18325 19.73775  1.000 16.15814  ? 196 ASN A HB2  1 
ATOM   2808 H HB3  . ASN A 1 182 ? 2.66453   -26.84154 19.13284  1.000 16.15814  ? 196 ASN A HB3  1 
ATOM   2809 H HD21 . ASN A 1 182 ? 0.53687   -27.28513 18.85119  0.088 22.37118  ? 196 ASN A HD21 1 
ATOM   2810 H HD22 . ASN A 1 182 ? -0.02043  -28.42481 18.07059  1.000 22.37118  ? 196 ASN A HD22 1 
ATOM   2811 N N    . VAL A 1 183 ? 3.76094   -27.52097 15.64225  1.000 12.42949  ? 197 VAL A N    1 
ATOM   2812 C CA   . VAL A 1 183 ? 3.40038   -26.87773 14.37606  1.000 12.89552  ? 197 VAL A CA   1 
ATOM   2813 C C    . VAL A 1 183 ? 1.96514   -26.38318 14.43906  1.000 13.97548  ? 197 VAL A C    1 
ATOM   2814 O O    . VAL A 1 183 ? 1.03222   -27.14932 14.70006  1.000 16.36669  ? 197 VAL A O    1 
ATOM   2815 C CB   . VAL A 1 183 ? 3.60720   -27.82070 13.18581  1.000 13.39183  ? 197 VAL A CB   1 
ATOM   2816 C CG1  . VAL A 1 183 ? 3.12678   -27.16251 11.90228  1.000 14.26068  ? 197 VAL A CG1  1 
ATOM   2817 C CG2  . VAL A 1 183 ? 5.05515   -28.16846 13.06872  1.000 14.14508  ? 197 VAL A CG2  1 
ATOM   2818 H H    . VAL A 1 183 ? 3.88860   -28.36962 15.58658  1.000 14.91028  ? 197 VAL A H    1 
ATOM   2819 H HA   . VAL A 1 183 ? 3.97786   -26.10743 14.25750  0.817 15.46952  ? 197 VAL A HA   1 
ATOM   2820 H HB   . VAL A 1 183 ? 3.09470   -28.63239 13.32512  0.899 16.06509  ? 197 VAL A HB   1 
ATOM   2821 H HG11 . VAL A 1 183 ? 3.44679   -27.67685 11.14469  1.000 17.10770  ? 197 VAL A HG11 1 
ATOM   2822 H HG12 . VAL A 1 183 ? 2.15701   -27.14155 11.90194  0.428 17.10770  ? 197 VAL A HG12 1 
ATOM   2823 H HG13 . VAL A 1 183 ? 3.47718   -26.25898 11.86039  1.000 17.10770  ? 197 VAL A HG13 1 
ATOM   2824 H HG21 . VAL A 1 183 ? 5.17301   -28.78529 12.32944  1.000 16.96899  ? 197 VAL A HG21 1 
ATOM   2825 H HG22 . VAL A 1 183 ? 5.56259   -27.35771 12.90717  1.000 16.96899  ? 197 VAL A HG22 1 
ATOM   2826 H HG23 . VAL A 1 183 ? 5.34823   -28.58294 13.89529  1.000 16.96899  ? 197 VAL A HG23 1 
ATOM   2827 N N    . VAL A 1 184 ? 1.78709   -25.09598 14.18893  1.000 12.45596  ? 198 VAL A N    1 
ATOM   2828 C CA   A VAL A 1 184 ? 0.46499   -24.49357 14.17497  0.750 13.43374  ? 198 VAL A CA   1 
ATOM   2829 C CA   B VAL A 1 184 ? 0.46300   -24.49509 14.17268  0.250 13.54140  ? 198 VAL A CA   1 
ATOM   2830 C C    . VAL A 1 184 ? 0.05263   -24.02079 12.78807  1.000 13.98315  ? 198 VAL A C    1 
ATOM   2831 O O    . VAL A 1 184 ? -1.14179  -23.78469 12.56969  1.000 16.66451  ? 198 VAL A O    1 
ATOM   2832 C CB   A VAL A 1 184 ? 0.35386   -23.34930 15.20523  0.750 14.38314  ? 198 VAL A CB   1 
ATOM   2833 C CB   B VAL A 1 184 ? 0.33081   -23.35060 15.19663  0.250 14.38084  ? 198 VAL A CB   1 
ATOM   2834 C CG1  A VAL A 1 184 ? 0.36607   -23.90886 16.61675  0.750 14.41709  ? 198 VAL A CG1  1 
ATOM   2835 C CG1  B VAL A 1 184 ? -1.13069  -23.00300 15.38887  0.250 15.33229  ? 198 VAL A CG1  1 
ATOM   2836 C CG2  A VAL A 1 184 ? 1.50166   -22.35296 15.04444  0.750 14.85791  ? 198 VAL A CG2  1 
ATOM   2837 C CG2  B VAL A 1 184 ? 0.97985   -23.73599 16.51709  0.250 14.15429  ? 198 VAL A CG2  1 
ATOM   2838 H H    . VAL A 1 184 ? 2.42446   -24.54323 14.02211  0.733 14.94205  ? 198 VAL A H    1 
ATOM   2839 H HA   . VAL A 1 184 ? -0.18063  -25.16730 14.43986  1.000 16.24458  ? 198 VAL A HA   1 
ATOM   2840 H HB   A VAL A 1 184 ? -0.48298  -22.88341 15.05179  0.750 17.25466  ? 198 VAL A HB   1 
ATOM   2841 H HB   B VAL A 1 184 ? 0.79139   -22.56434 14.86414  0.250 17.25190  ? 198 VAL A HB   1 
ATOM   2842 H HG11 A VAL A 1 184 ? 0.33697   -23.17324 17.24834  0.750 17.29540  ? 198 VAL A HG11 1 
ATOM   2843 H HG11 B VAL A 1 184 ? -1.23417  -22.52559 16.22689  0.250 18.39364  ? 198 VAL A HG11 1 
ATOM   2844 H HG12 A VAL A 1 184 ? -0.40935  -24.47907 16.73713  0.750 17.29540  ? 198 VAL A HG12 1 
ATOM   2845 H HG12 B VAL A 1 184 ? -1.42198  -22.44402 14.65158  0.250 18.39364  ? 198 VAL A HG12 1 
ATOM   2846 H HG13 A VAL A 1 184 ? 1.17821   -24.42342 16.74546  0.750 17.29540  ? 198 VAL A HG13 1 
ATOM   2847 H HG13 B VAL A 1 184 ? -1.65015  -23.82195 15.40840  0.250 18.39364  ? 198 VAL A HG13 1 
ATOM   2848 H HG21 A VAL A 1 184 ? 1.36952   -21.61665 15.66192  0.750 17.82438  ? 198 VAL A HG21 1 
ATOM   2849 H HG21 B VAL A 1 184 ? 0.71444   -23.09774 17.19759  0.250 16.98004  ? 198 VAL A HG21 1 
ATOM   2850 H HG22 A VAL A 1 184 ? 2.33915   -22.80187 15.23935  0.750 17.82438  ? 198 VAL A HG22 1 
ATOM   2851 H HG22 B VAL A 1 184 ? 0.68550   -24.62618 16.76572  0.250 16.98004  ? 198 VAL A HG22 1 
ATOM   2852 H HG23 A VAL A 1 184 ? 1.50779   -22.02277 14.13239  0.750 17.82438  ? 198 VAL A HG23 1 
ATOM   2853 H HG23 B VAL A 1 184 ? 1.94390   -23.72412 16.41046  0.250 16.98004  ? 198 VAL A HG23 1 
ATOM   2854 N N    . VAL A 1 185 ? 0.99453   -23.84595 11.86608  1.000 12.95631  ? 199 VAL A N    1 
ATOM   2855 C CA   . VAL A 1 185 ? 0.73339   -23.63095 10.44713  1.000 12.45173  ? 199 VAL A CA   1 
ATOM   2856 C C    . VAL A 1 185 ? 1.66289   -24.60372 9.74216   1.000 12.42699  ? 199 VAL A C    1 
ATOM   2857 O O    . VAL A 1 185 ? 2.88537   -24.50729 9.88463   1.000 12.19440  ? 199 VAL A O    1 
ATOM   2858 C CB   . VAL A 1 185 ? 1.01826   -22.18208 10.01245  1.000 13.03620  ? 199 VAL A CB   1 
ATOM   2859 C CG1  . VAL A 1 185 ? 0.97426   -22.04340 8.49630   1.000 13.62822  ? 199 VAL A CG1  1 
ATOM   2860 C CG2  . VAL A 1 185 ? 0.03399   -21.22696 10.67921  1.000 13.67532  ? 199 VAL A CG2  1 
ATOM   2861 H H    . VAL A 1 185 ? 1.83506   -23.84802 12.04805  1.000 15.54247  ? 199 VAL A H    1 
ATOM   2862 H HA   . VAL A 1 185 ? -0.19191  -23.81469 10.22140  1.000 14.93697  ? 199 VAL A HA   1 
ATOM   2863 H HB   . VAL A 1 185 ? 1.91391   -21.94236 10.29749  1.000 15.63833  ? 199 VAL A HB   1 
ATOM   2864 H HG11 . VAL A 1 185 ? 1.72521   -22.52333 8.11336   1.000 16.34876  ? 199 VAL A HG11 1 
ATOM   2865 H HG12 . VAL A 1 185 ? 0.14118   -22.41724 8.16902   1.000 16.34876  ? 199 VAL A HG12 1 
ATOM   2866 H HG13 . VAL A 1 185 ? 1.02904   -21.10336 8.26344   0.815 16.34876  ? 199 VAL A HG13 1 
ATOM   2867 H HG21 . VAL A 1 185 ? 0.26928   -20.31587 10.44371  1.000 16.40527  ? 199 VAL A HG21 1 
ATOM   2868 H HG22 . VAL A 1 185 ? -0.86210  -21.42836 10.36719  1.000 16.40527  ? 199 VAL A HG22 1 
ATOM   2869 H HG23 . VAL A 1 185 ? 0.08332   -21.34327 11.64094  0.889 16.40527  ? 199 VAL A HG23 1 
ATOM   2870 N N    . ASN A 1 186 ? 1.09643   -25.57785 9.04239   1.000 13.23451  ? 200 ASN A N    1 
ATOM   2871 C CA   . ASN A 1 186 ? 1.84506   -26.74456 8.57774   1.000 14.16236  ? 200 ASN A CA   1 
ATOM   2872 C C    . ASN A 1 186 ? 1.86723   -26.73869 7.05450   1.000 15.29038  ? 200 ASN A C    1 
ATOM   2873 O O    . ASN A 1 186 ? 0.94436   -27.24145 6.42052   1.000 16.78778  ? 200 ASN A O    1 
ATOM   2874 C CB   . ASN A 1 186 ? 1.19311   -27.99649 9.13624   1.000 14.66834  ? 200 ASN A CB   1 
ATOM   2875 C CG   . ASN A 1 186 ? 2.13475   -29.17955 9.17875   1.000 16.10837  ? 200 ASN A CG   1 
ATOM   2876 O OD1  . ASN A 1 186 ? 3.18276   -29.17718 8.54047   1.000 16.24123  ? 200 ASN A OD1  1 
ATOM   2877 N ND2  . ASN A 1 186 ? 1.75688   -30.20451 9.93303   1.000 18.22986  ? 200 ASN A ND2  1 
ATOM   2878 H H    . ASN A 1 186 ? 0.26585   -25.58750 8.81958   0.455 15.87630  ? 200 ASN A H    1 
ATOM   2879 H HA   . ASN A 1 186 ? 2.76820   -26.69232 8.87097   1.000 16.98973  ? 200 ASN A HA   1 
ATOM   2880 H HB2  . ASN A 1 186 ? 0.89338   -27.81943 10.04162  1.000 17.59690  ? 200 ASN A HB2  1 
ATOM   2881 H HB3  . ASN A 1 186 ? 0.43718   -28.23515 8.57722   1.000 17.59690  ? 200 ASN A HB3  1 
ATOM   2882 H HD21 . ASN A 1 186 ? 1.01279   -30.17076 10.36290  0.744 21.87073  ? 200 ASN A HD21 1 
ATOM   2883 H HD22 . ASN A 1 186 ? 2.25617   -30.90226 9.99180   0.643 21.87073  ? 200 ASN A HD22 1 
ATOM   2884 N N    . GLY A 1 187 ? 2.90645   -26.15539 6.46440   1.000 15.77148  ? 201 GLY A N    1 
ATOM   2885 C CA   . GLY A 1 187 ? 3.02096   -26.14306 5.01011   1.000 16.77246  ? 201 GLY A CA   1 
ATOM   2886 C C    . GLY A 1 187 ? 1.99150   -25.29675 4.28258   1.000 16.87351  ? 201 GLY A C    1 
ATOM   2887 O O    . GLY A 1 187 ? 1.45753   -25.72401 3.25311   1.000 18.63121  ? 201 GLY A O    1 
ATOM   2888 H H    . GLY A 1 187 ? 3.55094   -25.76449 6.87845   0.899 18.92067  ? 201 GLY A H    1 
ATOM   2889 H HA2  . GLY A 1 187 ? 3.89873   -25.80550 4.77244   1.000 20.12184  ? 201 GLY A HA2  1 
ATOM   2890 H HA3  . GLY A 1 187 ? 2.93419   -27.05316 4.68592   1.000 20.12184  ? 201 GLY A HA3  1 
ATOM   2891 N N    . GLN A 1 188 ? 1.68910   -24.11245 4.80320   1.000 15.71749  ? 202 GLN A N    1 
ATOM   2892 C CA   . GLN A 1 188 ? 0.85002   -23.15723 4.09187   1.000 14.89281  ? 202 GLN A CA   1 
ATOM   2893 C C    . GLN A 1 188 ? 1.47034   -22.79595 2.74892   1.000 15.50523  ? 202 GLN A C    1 
ATOM   2894 O O    . GLN A 1 188 ? 2.66949   -22.53196 2.64825   1.000 16.00918  ? 202 GLN A O    1 
ATOM   2895 C CB   . GLN A 1 188 ? 0.70085   -21.90648 4.96399   1.000 14.93311  ? 202 GLN A CB   1 
ATOM   2896 C CG   . GLN A 1 188 ? 0.25237   -20.62048 4.25922   1.000 14.98425  ? 202 GLN A CG   1 
ATOM   2897 C CD   . GLN A 1 188 ? -1.19607  -20.63631 3.86586   1.000 15.85280  ? 202 GLN A CD   1 
ATOM   2898 O OE1  . GLN A 1 188 ? -2.06907  -20.87759 4.69245   1.000 16.34889  ? 202 GLN A OE1  1 
ATOM   2899 N NE2  . GLN A 1 188 ? -1.47120  -20.36577 2.59112   1.000 16.51961  ? 202 GLN A NE2  1 
ATOM   2900 H H    . GLN A 1 188 ? 1.95872   -23.83580 5.57155   1.000 18.85588  ? 202 GLN A H    1 
ATOM   2901 H HA   . GLN A 1 188 ? -0.02605  -23.53483 3.91629   1.000 17.86626  ? 202 GLN A HA   1 
ATOM   2902 H HB2  . GLN A 1 188 ? 0.04299   -22.09674 5.65095   1.000 17.91462  ? 202 GLN A HB2  1 
ATOM   2903 H HB3  . GLN A 1 188 ? 1.56141   -21.72055 5.37114   1.000 17.91462  ? 202 GLN A HB3  1 
ATOM   2904 H HG2  . GLN A 1 188 ? 0.39061   -19.86950 4.85741   1.000 17.97599  ? 202 GLN A HG2  1 
ATOM   2905 H HG3  . GLN A 1 188 ? 0.77895   -20.50373 3.45300   1.000 17.97599  ? 202 GLN A HG3  1 
ATOM   2906 H HE21 . GLN A 1 188 ? -0.83322  -20.19383 2.04065   0.367 19.81843  ? 202 GLN A HE21 1 
ATOM   2907 H HE22 . GLN A 1 188 ? -2.28683  -20.36303 2.31848   1.000 19.81843  ? 202 GLN A HE22 1 
ATOM   2908 N N    . ASP A 1 189 ? 0.63034   -22.76316 1.71821   1.000 16.68478  ? 203 ASP A N    1 
ATOM   2909 C CA   . ASP A 1 189 ? 1.08341   -22.45432 0.36665   1.000 17.89398  ? 203 ASP A CA   1 
ATOM   2910 C C    . ASP A 1 189 ? 1.47629   -20.98666 0.26257   1.000 18.22210  ? 203 ASP A C    1 
ATOM   2911 O O    . ASP A 1 189 ? 0.69245   -20.10095 0.61266   1.000 19.95044  ? 203 ASP A O    1 
ATOM   2912 C CB   . ASP A 1 189 ? -0.06991  -22.74264 -0.58812  1.000 19.91996  ? 203 ASP A CB   1 
ATOM   2913 C CG   . ASP A 1 189 ? 0.31681   -22.65959 -2.05106  1.000 22.49800  ? 203 ASP A CG   1 
ATOM   2914 O OD1  . ASP A 1 189 ? 1.50838   -22.51699 -2.38654  1.000 23.52409  ? 203 ASP A OD1  1 
ATOM   2915 O OD2  . ASP A 1 189 ? -0.61241  -22.75470 -2.87905  1.000 24.77573  ? 203 ASP A OD2  1 
ATOM   2916 H H    . ASP A 1 189 ? -0.21381  -22.91729 1.77532   0.721 20.01663  ? 203 ASP A H    1 
ATOM   2917 H HA   . ASP A 1 189 ? 1.85819   -22.98965 0.13417   1.000 21.46767  ? 203 ASP A HA   1 
ATOM   2918 H HB2  . ASP A 1 189 ? -0.39892  -23.63937 -0.41922  0.897 23.89884  ? 203 ASP A HB2  1 
ATOM   2919 H HB3  . ASP A 1 189 ? -0.77513  -22.09543 -0.43102  1.000 23.89884  ? 203 ASP A HB3  1 
ATOM   2920 N N    . LEU A 1 190 ? 2.69986   -20.72948 -0.20965  1.000 16.44188  ? 204 LEU A N    1 
ATOM   2921 C CA   . LEU A 1 190 ? 3.15602   -19.37799 -0.51735  1.000 16.92334  ? 204 LEU A CA   1 
ATOM   2922 C C    . LEU A 1 190 ? 3.44954   -19.20452 -2.00084  1.000 17.48676  ? 204 LEU A C    1 
ATOM   2923 O O    . LEU A 1 190 ? 4.08923   -18.21915 -2.38700  1.000 18.11811  ? 204 LEU A O    1 
ATOM   2924 C CB   . LEU A 1 190 ? 4.40825   -19.01793 0.28793   1.000 17.54975  ? 204 LEU A CB   1 
ATOM   2925 C CG   . LEU A 1 190 ? 4.27527   -18.86213 1.79956   1.000 19.01609  ? 204 LEU A CG   1 
ATOM   2926 C CD1  . LEU A 1 190 ? 5.61451   -18.44229 2.34693   1.000 19.81132  ? 204 LEU A CD1  1 
ATOM   2927 C CD2  . LEU A 1 190 ? 3.21229   -17.84807 2.16638   1.000 21.29434  ? 204 LEU A CD2  1 
ATOM   2928 H H    . LEU A 1 190 ? 3.29189   -21.33445 -0.36166  1.000 19.72514  ? 204 LEU A H    1 
ATOM   2929 H HA   . LEU A 1 190 ? 2.45495   -18.75907 -0.25979  1.000 20.30290  ? 204 LEU A HA   1 
ATOM   2930 H HB2  . LEU A 1 190 ? 5.06450   -19.71628 0.13778   0.640 21.05459  ? 204 LEU A HB2  1 
ATOM   2931 H HB3  . LEU A 1 190 ? 4.74106   -18.17174 -0.04986  1.000 21.05459  ? 204 LEU A HB3  1 
ATOM   2932 H HG   . LEU A 1 190 ? 4.00102   -19.70488 2.19384   0.487 22.81420  ? 204 LEU A HG   1 
ATOM   2933 H HD11 . LEU A 1 190 ? 6.24092   -19.17604 2.24625   1.000 23.76848  ? 204 LEU A HD11 1 
ATOM   2934 H HD12 . LEU A 1 190 ? 5.92902   -17.66878 1.85329   0.033 23.76848  ? 204 LEU A HD12 1 
ATOM   2935 H HD13 . LEU A 1 190 ? 5.51585   -18.21802 3.28547   1.000 23.76848  ? 204 LEU A HD13 1 
ATOM   2936 H HD21 . LEU A 1 190 ? 2.34463   -18.18913 1.89852   1.000 25.54810  ? 204 LEU A HD21 1 
ATOM   2937 H HD22 . LEU A 1 190 ? 3.22978   -17.70517 3.12564   1.000 25.54810  ? 204 LEU A HD22 1 
ATOM   2938 H HD23 . LEU A 1 190 ? 3.39737   -17.01542 1.70449   1.000 25.54810  ? 204 LEU A HD23 1 
ATOM   2939 N N    . SER A 1 191 ? 3.00931   -20.13660 -2.84236  1.000 17.94257  ? 205 SER A N    1 
ATOM   2940 C CA   . SER A 1 191 ? 3.38695   -20.09027 -4.24892  1.000 19.60088  ? 205 SER A CA   1 
ATOM   2941 C C    . SER A 1 191 ? 2.80995   -18.88511 -4.97666  1.000 19.48176  ? 205 SER A C    1 
ATOM   2942 O O    . SER A 1 191 ? 3.32060   -18.52548 -6.03756  1.000 19.67050  ? 205 SER A O    1 
ATOM   2943 C CB   . SER A 1 191 ? 2.98548   -21.37958 -4.95437  1.000 22.08211  ? 205 SER A CB   1 
ATOM   2944 O OG   . SER A 1 191 ? 1.58149   -21.53249 -4.93663  1.000 23.81628  ? 205 SER A OG   1 
ATOM   2945 H H    . SER A 1 191 ? 2.49951   -20.79482 -2.62685  1.000 21.52597  ? 205 SER A H    1 
ATOM   2946 H HA   . SER A 1 191 ? 4.35319   -20.02124 -4.29915  0.193 23.51594  ? 205 SER A HA   1 
ATOM   2947 H HB2  . SER A 1 191 ? 3.28985   -21.34620 -5.87478  1.000 26.49343  ? 205 SER A HB2  1 
ATOM   2948 H HB3  . SER A 1 191 ? 3.39283   -22.13195 -4.49731  1.000 26.49343  ? 205 SER A HB3  1 
ATOM   2949 H HG   . SER A 1 191 ? 1.36792   -22.26579 -5.28628  1.000 28.57443  ? 205 SER A HG   1 
ATOM   2950 N N    . PHE A 1 192 ? 1.78843   -18.22861 -4.42993  1.000 19.06706  ? 206 PHE A N    1 
ATOM   2951 C CA   . PHE A 1 192 ? 1.36764   -16.96381 -5.01664  1.000 18.82737  ? 206 PHE A CA   1 
ATOM   2952 C C    . PHE A 1 192 ? 2.53600   -16.00007 -5.14601  1.000 18.63601  ? 206 PHE A C    1 
ATOM   2953 O O    . PHE A 1 192 ? 2.56199   -15.17077 -6.06351  1.000 19.68008  ? 206 PHE A O    1 
ATOM   2954 C CB   . PHE A 1 192 ? 0.27938   -16.31659 -4.16205  1.000 19.03696  ? 206 PHE A CB   1 
ATOM   2955 C CG   . PHE A 1 192 ? -0.06254  -14.92739 -4.59879  1.000 19.12297  ? 206 PHE A CG   1 
ATOM   2956 C CD1  . PHE A 1 192 ? -0.92358  -14.71315 -5.66196  1.000 20.23461  ? 206 PHE A CD1  1 
ATOM   2957 C CD2  . PHE A 1 192 ? 0.49654   -13.83151 -3.96946  1.000 20.53998  ? 206 PHE A CD2  1 
ATOM   2958 C CE1  . PHE A 1 192 ? -1.22396  -13.42013 -6.08579  1.000 20.77950  ? 206 PHE A CE1  1 
ATOM   2959 C CE2  . PHE A 1 192 ? 0.20789   -12.55009 -4.38147  1.000 21.05869  ? 206 PHE A CE2  1 
ATOM   2960 C CZ   . PHE A 1 192 ? -0.65166  -12.33929 -5.43849  1.000 21.27625  ? 206 PHE A CZ   1 
ATOM   2961 H H    . PHE A 1 192 ? 1.33903   -18.48607 -3.74337  1.000 22.87537  ? 206 PHE A H    1 
ATOM   2962 H HA   . PHE A 1 192 ? 1.00174   -17.14126 -5.89728  1.000 22.58774  ? 206 PHE A HA   1 
ATOM   2963 H HB2  . PHE A 1 192 ? -0.52600  -16.85423 -4.21872  1.000 22.83924  ? 206 PHE A HB2  1 
ATOM   2964 H HB3  . PHE A 1 192 ? 0.58568   -16.27377 -3.24268  1.000 22.83924  ? 206 PHE A HB3  1 
ATOM   2965 H HD1  . PHE A 1 192 ? -1.30564  -15.44035 -6.09798  1.000 24.27642  ? 206 PHE A HD1  1 
ATOM   2966 H HD2  . PHE A 1 192 ? 1.07780   -13.96190 -3.25529  0.348 24.64287  ? 206 PHE A HD2  1 
ATOM   2967 H HE1  . PHE A 1 192 ? -1.80522  -13.28449 -6.79898  1.000 24.93029  ? 206 PHE A HE1  1 
ATOM   2968 H HE2  . PHE A 1 192 ? 0.59372   -11.82476 -3.94565  0.642 25.26532  ? 206 PHE A HE2  1 
ATOM   2969 H HZ   . PHE A 1 192 ? -0.84631  -11.47317 -5.71571  0.725 25.52639  ? 206 PHE A HZ   1 
ATOM   2970 N N    . TRP A 1 193 ? 3.50899   -16.09841 -4.24582  1.000 17.75913  ? 207 TRP A N    1 
ATOM   2971 C CA   . TRP A 1 193 ? 4.64303   -15.19201 -4.18924  1.000 17.54981  ? 207 TRP A CA   1 
ATOM   2972 C C    . TRP A 1 193 ? 5.85360   -15.68581 -4.97092  1.000 18.56076  ? 207 TRP A C    1 
ATOM   2973 O O    . TRP A 1 193 ? 6.91321   -15.05107 -4.90523  1.000 18.58293  ? 207 TRP A O    1 
ATOM   2974 C CB   . TRP A 1 193 ? 5.02679   -14.95364 -2.72630  1.000 17.53083  ? 207 TRP A CB   1 
ATOM   2975 C CG   . TRP A 1 193 ? 3.93457   -14.27644 -1.97534  1.000 16.56111  ? 207 TRP A CG   1 
ATOM   2976 C CD1  . TRP A 1 193 ? 3.10330   -14.82808 -1.04787  1.000 16.60214  ? 207 TRP A CD1  1 
ATOM   2977 C CD2  . TRP A 1 193 ? 3.52254   -12.91557 -2.12481  1.000 17.35871  ? 207 TRP A CD2  1 
ATOM   2978 N NE1  . TRP A 1 193 ? 2.21452   -13.88804 -0.59598  1.000 16.76066  ? 207 TRP A NE1  1 
ATOM   2979 C CE2  . TRP A 1 193 ? 2.44682   -12.70526 -1.24537  1.000 16.97138  ? 207 TRP A CE2  1 
ATOM   2980 C CE3  . TRP A 1 193 ? 3.96169   -11.85310 -2.92072  1.000 17.91481  ? 207 TRP A CE3  1 
ATOM   2981 C CZ2  . TRP A 1 193 ? 1.81051   -11.47342 -1.12760  1.000 18.88269  ? 207 TRP A CZ2  1 
ATOM   2982 C CZ3  . TRP A 1 193 ? 3.32426   -10.62894 -2.80278  1.000 19.30521  ? 207 TRP A CZ3  1 
ATOM   2983 C CH2  . TRP A 1 193 ? 2.26329   -10.45116 -1.91470  1.000 19.65499  ? 207 TRP A CH2  1 
ATOM   2984 H H    . TRP A 1 193 ? 3.53265   -16.70495 -3.63661  0.694 21.30585  ? 207 TRP A H    1 
ATOM   2985 H HA   . TRP A 1 193 ? 4.38111   -14.34492 -4.58260  1.000 21.05466  ? 207 TRP A HA   1 
ATOM   2986 H HB2  . TRP A 1 193 ? 5.20711   -15.80596 -2.29977  1.000 21.03189  ? 207 TRP A HB2  1 
ATOM   2987 H HB3  . TRP A 1 193 ? 5.81608   -14.39096 -2.69008  1.000 21.03189  ? 207 TRP A HB3  1 
ATOM   2988 H HD1  . TRP A 1 193 ? 3.13440   -15.71286 -0.76311  1.000 19.91745  ? 207 TRP A HD1  1 
ATOM   2989 H HE1  . TRP A 1 193 ? 1.60835   -14.01981 -0.00033  1.000 20.10769  ? 207 TRP A HE1  1 
ATOM   2990 H HE3  . TRP A 1 193 ? 4.66675   -11.96592 -3.51659  1.000 21.49267  ? 207 TRP A HE3  1 
ATOM   2991 H HZ2  . TRP A 1 193 ? 1.10381   -11.35006 -0.53577  0.350 22.65412  ? 207 TRP A HZ2  1 
ATOM   2992 H HZ3  . TRP A 1 193 ? 3.60845   -9.91345  -3.32452  1.000 23.16115  ? 207 TRP A HZ3  1 
ATOM   2993 H HH2  . TRP A 1 193 ? 1.85439   -9.61789  -1.85663  0.725 23.58088  ? 207 TRP A HH2  1 
ATOM   2994 N N    . ASP A 1 194 ? 5.73499   -16.79227 -5.69679  1.000 19.52313  ? 208 ASP A N    1 
ATOM   2995 C CA   . ASP A 1 194 ? 6.85199   -17.26653 -6.50064  1.000 21.06182  ? 208 ASP A CA   1 
ATOM   2996 C C    . ASP A 1 194 ? 7.36788   -16.13770 -7.38101  1.000 21.74142  ? 208 ASP A C    1 
ATOM   2997 O O    . ASP A 1 194 ? 6.59047   -15.42515 -8.01448  1.000 22.89379  ? 208 ASP A O    1 
ATOM   2998 C CB   . ASP A 1 194 ? 6.39777   -18.43578 -7.37545  1.000 22.09838  ? 208 ASP A CB   1 
ATOM   2999 C CG   . ASP A 1 194 ? 6.27106   -19.73294 -6.59963  1.000 23.88010  ? 208 ASP A CG   1 
ATOM   3000 O OD1  . ASP A 1 194 ? 6.57952   -19.74268 -5.38888  1.000 24.34445  ? 208 ASP A OD1  1 
ATOM   3001 O OD2  . ASP A 1 194 ? 5.86571   -20.74837 -7.20106  1.000 26.23962  ? 208 ASP A OD2  1 
ATOM   3002 H H    . ASP A 1 194 ? 5.02752   -17.27934 -5.73985  1.000 23.42265  ? 208 ASP A H    1 
ATOM   3003 H HA   . ASP A 1 194 ? 7.56746   -17.57372 -5.92217  1.000 25.26908  ? 208 ASP A HA   1 
ATOM   3004 H HB2  . ASP A 1 194 ? 5.53014   -18.22768 -7.75599  0.111 26.51295  ? 208 ASP A HB2  1 
ATOM   3005 H HB3  . ASP A 1 194 ? 7.04664   -18.57173 -8.08353  1.000 26.51295  ? 208 ASP A HB3  1 
ATOM   3006 N N    . GLY A 1 195 ? 8.68296   -15.94869 -7.38313  1.000 22.44482  ? 209 GLY A N    1 
ATOM   3007 C CA   . GLY A 1 195 ? 9.29480   -14.92079 -8.19191  1.000 22.52498  ? 209 GLY A CA   1 
ATOM   3008 C C    . GLY A 1 195 ? 9.45758   -13.57538 -7.51855  1.000 21.50080  ? 209 GLY A C    1 
ATOM   3009 O O    . GLY A 1 195 ? 10.17496  -12.71940 -8.05484  1.000 22.26245  ? 209 GLY A O    1 
ATOM   3010 H H    . GLY A 1 195 ? 9.24030   -16.41029 -6.91849  0.627 26.92867  ? 209 GLY A H    1 
ATOM   3011 H HA2  . GLY A 1 195 ? 10.17658  -15.22336 -8.45989  1.000 27.02487  ? 209 GLY A HA2  1 
ATOM   3012 H HA3  . GLY A 1 195 ? 8.75191   -14.78831 -8.98476  1.000 27.02487  ? 209 GLY A HA3  1 
ATOM   3013 N N    . THR A 1 196 ? 8.81726   -13.34542 -6.37596  1.000 20.44282  ? 210 THR A N    1 
ATOM   3014 C CA   . THR A 1 196 ? 9.05655   -12.12221 -5.61947  1.000 19.95433  ? 210 THR A CA   1 
ATOM   3015 C C    . THR A 1 196 ? 10.40966  -12.26394 -4.92977  1.000 20.47980  ? 210 THR A C    1 
ATOM   3016 O O    . THR A 1 196 ? 10.57856  -13.10645 -4.04582  1.000 21.75404  ? 210 THR A O    1 
ATOM   3017 C CB   . THR A 1 196 ? 7.93198   -11.89841 -4.61454  1.000 20.76050  ? 210 THR A CB   1 
ATOM   3018 O OG1  . THR A 1 196 ? 6.70905   -11.63555 -5.31370  1.000 21.95041  ? 210 THR A OG1  1 
ATOM   3019 C CG2  . THR A 1 196 ? 8.24541   -10.71677 -3.71496  1.000 22.11399  ? 210 THR A CG2  1 
ATOM   3020 H H    . THR A 1 196 ? 8.24373   -13.87906 -6.02114  1.000 24.52627  ? 210 THR A H    1 
ATOM   3021 H HA   . THR A 1 196 ? 9.08237   -11.35287 -6.20969  1.000 23.94009  ? 210 THR A HA   1 
ATOM   3022 H HB   . THR A 1 196 ? 7.83319   -12.69056 -4.06349  1.000 24.90749  ? 210 THR A HB   1 
ATOM   3023 H HG1  . THR A 1 196 ? 6.48479   -12.30868 -5.76337  0.256 26.33539  ? 210 THR A HG1  1 
ATOM   3024 H HG21 . THR A 1 196 ? 7.44130   -10.42601 -3.25697  1.000 26.53167  ? 210 THR A HG21 1 
ATOM   3025 H HG22 . THR A 1 196 ? 8.90977   -10.96937 -3.05487  1.000 26.53167  ? 210 THR A HG22 1 
ATOM   3026 H HG23 . THR A 1 196 ? 8.59069   -9.98010  -4.24316  1.000 26.53167  ? 210 THR A HG23 1 
ATOM   3027 N N    . ASP A 1 197 ? 11.37520  -11.43992 -5.31838  1.000 19.75938  ? 211 ASP A N    1 
ATOM   3028 C CA   . ASP A 1 197 ? 12.76223  -11.61810 -4.91584  1.000 20.31984  ? 211 ASP A CA   1 
ATOM   3029 C C    . ASP A 1 197 ? 13.17254  -10.70382 -3.77654  1.000 19.16533  ? 211 ASP A C    1 
ATOM   3030 O O    . ASP A 1 197 ? 14.36903  -10.61120 -3.46754  1.000 19.70605  ? 211 ASP A O    1 
ATOM   3031 C CB   . ASP A 1 197 ? 13.66748  -11.37925 -6.11846  1.000 22.35998  ? 211 ASP A CB   1 
ATOM   3032 C CG   . ASP A 1 197 ? 13.46298  -12.41132 -7.19652  1.000 24.73075  ? 211 ASP A CG   1 
ATOM   3033 O OD1  . ASP A 1 197 ? 13.18900  -13.57759 -6.84363  1.000 27.38632  ? 211 ASP A OD1  1 
ATOM   3034 O OD2  . ASP A 1 197 ? 13.56955  -12.06546 -8.39134  1.000 25.18158  ? 211 ASP A OD2  1 
ATOM   3035 H H    . ASP A 1 197 ? 11.24803  -10.75708 -5.82549  1.000 23.70615  ? 211 ASP A H    1 
ATOM   3036 H HA   . ASP A 1 197 ? 12.88165  -12.53065 -4.60942  1.000 24.37869  ? 211 ASP A HA   1 
ATOM   3037 H HB2  . ASP A 1 197 ? 13.47377  -10.50636 -6.49455  0.910 26.82687  ? 211 ASP A HB2  1 
ATOM   3038 H HB3  . ASP A 1 197 ? 14.59363  -11.41937 -5.83292  1.000 26.82687  ? 211 ASP A HB3  1 
ATOM   3039 N N    . SER A 1 198 ? 12.20745  -10.05095 -3.13045  1.000 18.26111  ? 212 SER A N    1 
ATOM   3040 C CA   . SER A 1 198 ? 12.47908  -8.97783  -2.18749  1.000 17.60521  ? 212 SER A CA   1 
ATOM   3041 C C    . SER A 1 198 ? 12.00157  -9.30551  -0.77997  1.000 16.18189  ? 212 SER A C    1 
ATOM   3042 O O    . SER A 1 198 ? 11.84180  -8.38888  0.03342   1.000 16.50441  ? 212 SER A O    1 
ATOM   3043 C CB   . SER A 1 198 ? 11.82270  -7.68386  -2.66233  1.000 18.17999  ? 212 SER A CB   1 
ATOM   3044 O OG   . SER A 1 198 ? 10.42191  -7.83747  -2.75138  1.000 18.64166  ? 212 SER A OG   1 
ATOM   3045 H H    . SER A 1 198 ? 11.36937  -10.21827 -3.22650  0.404 21.90822  ? 212 SER A H    1 
ATOM   3046 H HA   . SER A 1 198 ? 13.43936  -8.84656  -2.14838  1.000 21.12115  ? 212 SER A HA   1 
ATOM   3047 H HB2  . SER A 1 198 ? 12.02366  -6.97664  -2.02958  1.000 21.81087  ? 212 SER A HB2  1 
ATOM   3048 H HB3  . SER A 1 198 ? 12.17199  -7.45486  -3.53780  0.267 21.81087  ? 212 SER A HB3  1 
ATOM   3049 H HG   . SER A 1 198 ? 10.23397  -8.44850  -3.29629  0.564 22.36489  ? 212 SER A HG   1 
ATOM   3050 N N    . CYS A 1 199 ? 11.76906  -10.58075 -0.46857  1.000 15.57748  ? 213 CYS A N    1 
ATOM   3051 C CA   . CYS A 1 199 ? 11.28637  -10.94302 0.85721   1.000 14.17208  ? 213 CYS A CA   1 
ATOM   3052 C C    . CYS A 1 199 ? 12.39103  -10.84112 1.89750   1.000 13.95607  ? 213 CYS A C    1 
ATOM   3053 O O    . CYS A 1 199 ? 13.57762  -11.00381 1.60507   1.000 14.85981  ? 213 CYS A O    1 
ATOM   3054 C CB   . CYS A 1 199 ? 10.74118  -12.36962 0.86186   1.000 16.29868  ? 213 CYS A CB   1 
ATOM   3055 S SG   . CYS A 1 199 ? 9.34683   -12.65842 -0.22570  1.000 17.69332  ? 213 CYS A SG   1 
ATOM   3056 H H    . CYS A 1 199 ? 11.88232  -11.24534 -1.00251  1.000 18.68786  ? 213 CYS A H    1 
ATOM   3057 H HA   . CYS A 1 199 ? 10.57433  -10.33028 1.09895   1.000 17.00139  ? 213 CYS A HA   1 
ATOM   3058 H HB2  . CYS A 1 199 ? 11.45211  -12.96969 0.58728   1.000 19.55331  ? 213 CYS A HB2  1 
ATOM   3059 H HB3  . CYS A 1 199 ? 10.45507  -12.58482 1.76337   0.533 19.55331  ? 213 CYS A HB3  1 
ATOM   3060 H HG   . CYS A 1 199 ? 9.70300   -12.51875 -1.36308  1.000 21.22688  ? 213 CYS A HG   1 
ATOM   3061 N N    . TYR A 1 200 ? 11.97489  -10.59372 3.13469   1.000 12.53669  ? 214 TYR A N    1 
ATOM   3062 C CA   . TYR A 1 200 ? 12.90235  -10.46103 4.24755   1.000 12.45543  ? 214 TYR A CA   1 
ATOM   3063 C C    . TYR A 1 200 ? 12.13350  -10.63844 5.54914   1.000 11.85253  ? 214 TYR A C    1 
ATOM   3064 O O    . TYR A 1 200 ? 10.92042  -10.42705 5.60747   1.000 11.95712  ? 214 TYR A O    1 
ATOM   3065 C CB   . TYR A 1 200 ? 13.59674  -9.10017  4.23271   1.000 12.45707  ? 214 TYR A CB   1 
ATOM   3066 C CG   . TYR A 1 200 ? 12.66740  -7.91243  4.21282   1.000 12.64294  ? 214 TYR A CG   1 
ATOM   3067 C CD1  . TYR A 1 200 ? 12.18713  -7.41050  3.01351   1.000 13.59691  ? 214 TYR A CD1  1 
ATOM   3068 C CD2  . TYR A 1 200 ? 12.26548  -7.28939  5.38131   1.000 13.03237  ? 214 TYR A CD2  1 
ATOM   3069 C CE1  . TYR A 1 200 ? 11.33661  -6.31633  2.97838   1.000 14.24737  ? 214 TYR A CE1  1 
ATOM   3070 C CE2  . TYR A 1 200 ? 11.42672  -6.19546  5.35260   1.000 13.70336  ? 214 TYR A CE2  1 
ATOM   3071 C CZ   . TYR A 1 200 ? 10.96508  -5.70869  4.15553   1.000 14.60428  ? 214 TYR A CZ   1 
ATOM   3072 O OH   . TYR A 1 200 ? 10.12536  -4.61963  4.17543   1.000 17.20220  ? 214 TYR A OH   1 
ATOM   3073 H H    . TYR A 1 200 ? 11.14969  -10.49749 3.35692   0.641 15.03892  ? 214 TYR A H    1 
ATOM   3074 H HA   . TYR A 1 200 ? 13.57521  -11.15707 4.18689   1.000 14.94140  ? 214 TYR A HA   1 
ATOM   3075 H HB2  . TYR A 1 200 ? 14.14594  -9.02672  5.02888   1.000 14.94338  ? 214 TYR A HB2  1 
ATOM   3076 H HB3  . TYR A 1 200 ? 14.15313  -9.04771  3.43988   1.000 14.94338  ? 214 TYR A HB3  1 
ATOM   3077 H HD1  . TYR A 1 200 ? 12.44065  -7.81607  2.21592   1.000 16.31118  ? 214 TYR A HD1  1 
ATOM   3078 H HD2  . TYR A 1 200 ? 12.56608  -7.61388  6.19938   0.858 15.63374  ? 214 TYR A HD2  1 
ATOM   3079 H HE1  . TYR A 1 200 ? 11.01952  -5.99542  2.16513   1.000 17.09174  ? 214 TYR A HE1  1 
ATOM   3080 H HE2  . TYR A 1 200 ? 11.17274  -5.78574  6.14791   1.000 16.43893  ? 214 TYR A HE2  1 
ATOM   3081 H HH   . TYR A 1 200 ? 9.90211   -4.44338  4.96580   1.000 20.63753  ? 214 TYR A HH   1 
ATOM   3082 N N    . PHE A 1 201 ? 12.85777  -11.00472 6.59986   1.000 11.25235  ? 215 PHE A N    1 
ATOM   3083 C CA   . PHE A 1 201 ? 12.28301  -11.10051 7.93257   1.000 10.46616  ? 215 PHE A CA   1 
ATOM   3084 C C    . PHE A 1 201 ? 12.31395  -9.75866  8.64868   1.000 10.66850  ? 215 PHE A C    1 
ATOM   3085 O O    . PHE A 1 201 ? 13.19140  -8.91714  8.42689   1.000 11.08362  ? 215 PHE A O    1 
ATOM   3086 C CB   . PHE A 1 201 ? 13.05666  -12.11660 8.77202   1.000 10.68725  ? 215 PHE A CB   1 
ATOM   3087 C CG   . PHE A 1 201 ? 12.86135  -13.56259 8.36330   1.000 11.43053  ? 215 PHE A CG   1 
ATOM   3088 C CD1  . PHE A 1 201 ? 11.60549  -14.13659 8.34065   1.000 12.09087  ? 215 PHE A CD1  1 
ATOM   3089 C CD2  . PHE A 1 201 ? 13.95193  -14.35678 8.03969   1.000 12.98955  ? 215 PHE A CD2  1 
ATOM   3090 C CE1  . PHE A 1 201 ? 11.45629  -15.46383 7.98104   1.000 13.17538  ? 215 PHE A CE1  1 
ATOM   3091 C CE2  . PHE A 1 201 ? 13.79832  -15.66986 7.68865   1.000 14.11988  ? 215 PHE A CE2  1 
ATOM   3092 C CZ   . PHE A 1 201 ? 12.55999  -16.22500 7.66335   1.000 14.05363  ? 215 PHE A CZ   1 
ATOM   3093 H H    . PHE A 1 201 ? 13.69343  -11.20485 6.56490   1.000 13.49771  ? 215 PHE A H    1 
ATOM   3094 H HA   . PHE A 1 201 ? 11.35854  -11.38224 7.84953   1.000 12.55428  ? 215 PHE A HA   1 
ATOM   3095 H HB2  . PHE A 1 201 ? 14.00342  -11.91867 8.69878   1.000 12.81959  ? 215 PHE A HB2  1 
ATOM   3096 H HB3  . PHE A 1 201 ? 12.77089  -12.03386 9.69527   0.866 12.81959  ? 215 PHE A HB3  1 
ATOM   3097 H HD1  . PHE A 1 201 ? 10.85920  -13.63013 8.56745   1.000 14.50394  ? 215 PHE A HD1  1 
ATOM   3098 H HD2  . PHE A 1 201 ? 14.80562  -13.98852 8.06191   1.000 15.58236  ? 215 PHE A HD2  1 
ATOM   3099 H HE1  . PHE A 1 201 ? 10.60792  -15.84385 7.95359   1.000 15.80534  ? 215 PHE A HE1  1 
ATOM   3100 H HE2  . PHE A 1 201 ? 14.54226  -16.18219 7.46734   1.000 16.93874  ? 215 PHE A HE2  1 
ATOM   3101 H HZ   . PHE A 1 201 ? 12.45641  -17.11965 7.43146   0.736 16.85925  ? 215 PHE A HZ   1 
ATOM   3102 N N    . LYS A 1 202 ? 11.35866  -9.58948  9.55441   1.000 10.10886  ? 216 LYS A N    1 
ATOM   3103 C CA   . LYS A 1 202 ? 11.34441  -8.49426  10.51348  1.000 10.38367  ? 216 LYS A CA   1 
ATOM   3104 C C    . LYS A 1 202 ? 10.91983  -9.03575  11.86165  1.000 9.32360   ? 216 LYS A C    1 
ATOM   3105 O O    . LYS A 1 202 ? 10.23302  -10.05040 11.95978  1.000 9.78755   ? 216 LYS A O    1 
ATOM   3106 C CB   . LYS A 1 202 ? 10.33454  -7.40040  10.13875  1.000 10.81712  ? 216 LYS A CB   1 
ATOM   3107 C CG   . LYS A 1 202 ? 10.39918  -6.94349  8.69214   1.000 12.31868  ? 216 LYS A CG   1 
ATOM   3108 C CD   . LYS A 1 202 ? 9.59192   -5.66608  8.48060   1.000 12.60849  ? 216 LYS A CD   1 
ATOM   3109 C CE   . LYS A 1 202 ? 10.42356  -4.43165  8.79603   1.000 14.18393  ? 216 LYS A CE   1 
ATOM   3110 N NZ   . LYS A 1 202 ? 9.61135   -3.19497  8.82095   1.000 14.60964  ? 216 LYS A NZ   1 
ATOM   3111 H H    . LYS A 1 202 ? 10.68318  -10.11544 9.63621   1.000 12.12553  ? 216 LYS A H    1 
ATOM   3112 H HA   . LYS A 1 202 ? 12.23757  -8.11783  10.55194  1.000 12.45530  ? 216 LYS A HA   1 
ATOM   3113 H HB2  . LYS A 1 202 ? 9.43989   -7.73977  10.29789  1.000 12.97544  ? 216 LYS A HB2  1 
ATOM   3114 H HB3  . LYS A 1 202 ? 10.49939  -6.62475  10.69741  1.000 12.97544  ? 216 LYS A HB3  1 
ATOM   3115 H HG2  . LYS A 1 202 ? 11.32180  -6.76608  8.45090   0.822 14.77731  ? 216 LYS A HG2  1 
ATOM   3116 H HG3  . LYS A 1 202 ? 10.03349  -7.63522  8.11882   0.423 14.77731  ? 216 LYS A HG3  1 
ATOM   3117 H HD2  . LYS A 1 202 ? 9.30634   -5.61458  7.55502   1.000 15.12508  ? 216 LYS A HD2  1 
ATOM   3118 H HD3  . LYS A 1 202 ? 8.81885   -5.67237  9.06645   1.000 15.12508  ? 216 LYS A HD3  1 
ATOM   3119 H HE2  . LYS A 1 202 ? 10.83428  -4.53978  9.66811   1.000 17.01561  ? 216 LYS A HE2  1 
ATOM   3120 H HE3  . LYS A 1 202 ? 11.10866  -4.32832  8.11717   0.718 17.01561  ? 216 LYS A HE3  1 
ATOM   3121 H HZ1  . LYS A 1 202 ? 9.98007   -2.57800  8.29608   0.449 17.52646  ? 216 LYS A HZ1  1 
ATOM   3122 H HZ2  . LYS A 1 202 ? 8.78749   -3.36597  8.53095   0.264 17.52646  ? 216 LYS A HZ2  1 
ATOM   3123 H HZ3  . LYS A 1 202 ? 9.56527   -2.87774  9.65122   1.000 17.52646  ? 216 LYS A HZ3  1 
ATOM   3124 N N    . ALA A 1 203 ? 11.29799  -8.31724  12.91313  1.000 9.48743   ? 217 ALA A N    1 
ATOM   3125 C CA   . ALA A 1 203 ? 10.80643  -8.64964  14.23784  1.000 9.85339   ? 217 ALA A CA   1 
ATOM   3126 C C    . ALA A 1 203 ? 10.93824  -7.43142  15.12942  1.000 9.96080   ? 217 ALA A C    1 
ATOM   3127 O O    . ALA A 1 203 ? 11.86575  -6.64055  14.98230  1.000 11.29502  ? 217 ALA A O    1 
ATOM   3128 C CB   . ALA A 1 203 ? 11.58349  -9.81361  14.85786  1.000 10.93839  ? 217 ALA A CB   1 
ATOM   3129 H H    . ALA A 1 203 ? 11.83078  -7.64284  12.88279  1.000 11.37980  ? 217 ALA A H    1 
ATOM   3130 H HA   . ALA A 1 203 ? 9.87094   -8.89709  14.17068  1.000 11.81896  ? 217 ALA A HA   1 
ATOM   3131 H HB1  . ALA A 1 203 ? 11.53296  -10.57895 14.26405  1.000 13.12096  ? 217 ALA A HB1  1 
ATOM   3132 H HB2  . ALA A 1 203 ? 12.50874  -9.54782  14.97690  1.000 13.12096  ? 217 ALA A HB2  1 
ATOM   3133 H HB3  . ALA A 1 203 ? 11.18971  -10.03449 15.71638  1.000 13.12096  ? 217 ALA A HB3  1 
ATOM   3134 N N    . GLY A 1 204 ? 10.03669  -7.32293  16.08981  1.000 9.82727   ? 218 GLY A N    1 
ATOM   3135 C CA   . GLY A 1 204 ? 10.06389  -6.22308  17.03781  1.000 10.20519  ? 218 GLY A CA   1 
ATOM   3136 C C    . GLY A 1 204 ? 8.66386   -5.86934  17.45462  1.000 9.75916   ? 218 GLY A C    1 
ATOM   3137 O O    . GLY A 1 204 ? 7.91601   -6.73503  17.92002  1.000 10.57629  ? 218 GLY A O    1 
ATOM   3138 H H    . GLY A 1 204 ? 9.39222   -7.87825  16.21583  1.000 11.78762  ? 218 GLY A H    1 
ATOM   3139 H HA2  . GLY A 1 204 ? 10.57293  -6.47695  17.82351  1.000 12.24112  ? 218 GLY A HA2  1 
ATOM   3140 H HA3  . GLY A 1 204 ? 10.47817  -5.44631  16.63051  1.000 12.24112  ? 218 GLY A HA3  1 
ATOM   3141 N N    . ALA A 1 205 ? 8.29789   -4.60193  17.28386  1.000 10.51625  ? 219 ALA A N    1 
ATOM   3142 C CA   . ALA A 1 205 ? 6.95319   -4.14447  17.61125  1.000 10.98396  ? 219 ALA A CA   1 
ATOM   3143 C C    . ALA A 1 205 ? 6.48855   -3.16461  16.54395  1.000 10.85927  ? 219 ALA A C    1 
ATOM   3144 O O    . ALA A 1 205 ? 7.07092   -2.08586  16.36852  1.000 12.27900  ? 219 ALA A O    1 
ATOM   3145 C CB   . ALA A 1 205 ? 6.91774   -3.48058  18.99334  1.000 11.65669  ? 219 ALA A CB   1 
ATOM   3146 H H    . ALA A 1 205 ? 8.81418   -3.98583  16.97815  0.939 12.61439  ? 219 ALA A H    1 
ATOM   3147 H HA   . ALA A 1 205 ? 6.34950   -4.90372  17.61251  1.000 13.17565  ? 219 ALA A HA   1 
ATOM   3148 H HB1  . ALA A 1 205 ? 7.41286   -2.64729  18.95620  1.000 13.98292  ? 219 ALA A HB1  1 
ATOM   3149 H HB2  . ALA A 1 205 ? 5.99499   -3.30651  19.23650  1.000 13.98292  ? 219 ALA A HB2  1 
ATOM   3150 H HB3  . ALA A 1 205 ? 7.32348   -4.07783  19.64108  1.000 13.98292  ? 219 ALA A HB3  1 
ATOM   3151 N N    . TYR A 1 206 ? 5.40042   -3.51404  15.86892  1.000 11.24722  ? 220 TYR A N    1 
ATOM   3152 C CA   . TYR A 1 206 ? 4.78708   -2.67180  14.85545  1.000 11.65678  ? 220 TYR A CA   1 
ATOM   3153 C C    . TYR A 1 206 ? 3.33317   -2.52045  15.26828  1.000 11.68916  ? 220 TYR A C    1 
ATOM   3154 O O    . TYR A 1 206 ? 2.60838   -3.50889  15.37736  1.000 12.40685  ? 220 TYR A O    1 
ATOM   3155 C CB   . TYR A 1 206 ? 4.98555   -3.34612  13.50212  1.000 12.45947  ? 220 TYR A CB   1 
ATOM   3156 C CG   . TYR A 1 206 ? 4.21911   -2.78025  12.33408  1.000 13.73198  ? 220 TYR A CG   1 
ATOM   3157 C CD1  . TYR A 1 206 ? 4.01250   -1.41174  12.18732  1.000 14.37520  ? 220 TYR A CD1  1 
ATOM   3158 C CD2  . TYR A 1 206 ? 3.70961   -3.62145  11.36472  1.000 15.06661  ? 220 TYR A CD2  1 
ATOM   3159 C CE1  . TYR A 1 206 ? 3.31323   -0.90262  11.10027  1.000 16.33486  ? 220 TYR A CE1  1 
ATOM   3160 C CE2  . TYR A 1 206 ? 3.01805   -3.12281  10.27109  1.000 15.85591  ? 220 TYR A CE2  1 
ATOM   3161 C CZ   . TYR A 1 206 ? 2.82042   -1.76379  10.15133  1.000 17.20257  ? 220 TYR A CZ   1 
ATOM   3162 O OH   . TYR A 1 206 ? 2.13799   -1.24775  9.07520   1.000 20.38966  ? 220 TYR A OH   1 
ATOM   3163 H H    . TYR A 1 206 ? 4.98707   -4.25913  15.98548  0.198 13.49156  ? 220 TYR A H    1 
ATOM   3164 H HA   . TYR A 1 206 ? 5.15750   -1.77768  14.79033  1.000 13.98303  ? 220 TYR A HA   1 
ATOM   3165 H HB2  . TYR A 1 206 ? 5.92696   -3.28957  13.27528  1.000 14.94625  ? 220 TYR A HB2  1 
ATOM   3166 H HB3  . TYR A 1 206 ? 4.72056   -4.27513  13.58943  1.000 14.94625  ? 220 TYR A HB3  1 
ATOM   3167 H HD1  . TYR A 1 206 ? 4.34855   -0.82776  12.82837  1.000 17.24513  ? 220 TYR A HD1  1 
ATOM   3168 H HD2  . TYR A 1 206 ? 3.83258   -4.53962  11.44687  1.000 18.07483  ? 220 TYR A HD2  1 
ATOM   3169 H HE1  . TYR A 1 206 ? 3.18003   0.01393   11.01604  1.000 19.59673  ? 220 TYR A HE1  1 
ATOM   3170 H HE2  . TYR A 1 206 ? 2.68937   -3.70206  9.62198   0.708 19.02199  ? 220 TYR A HE2  1 
ATOM   3171 H HH   . TYR A 1 206 ? 1.66372   -1.84473  8.72265   0.074 24.46248  ? 220 TYR A HH   1 
ATOM   3172 N N    . ASN A 1 207 ? 2.94314   -1.29845  15.59280  1.000 12.55020  ? 221 ASN A N    1 
ATOM   3173 C CA   . ASN A 1 207 ? 1.69679   -1.01158  16.30742  1.000 13.12917  ? 221 ASN A CA   1 
ATOM   3174 C C    . ASN A 1 207 ? 0.56616   -0.78177  15.31207  1.000 13.70279  ? 221 ASN A C    1 
ATOM   3175 O O    . ASN A 1 207 ? 0.58005   0.20329   14.57156  1.000 15.38488  ? 221 ASN A O    1 
ATOM   3176 C CB   . ASN A 1 207 ? 1.92952   0.22998   17.15787  1.000 13.67833  ? 221 ASN A CB   1 
ATOM   3177 C CG   . ASN A 1 207 ? 0.83926   0.47921   18.16021  1.000 14.28068  ? 221 ASN A CG   1 
ATOM   3178 O OD1  . ASN A 1 207 ? 0.16898   -0.44283  18.62860  1.000 16.47513  ? 221 ASN A OD1  1 
ATOM   3179 N ND2  . ASN A 1 207 ? 0.67527   1.74223   18.52775  1.000 15.68641  ? 221 ASN A ND2  1 
ATOM   3180 H H    . ASN A 1 207 ? 3.39442   -0.59048  15.40641  0.415 15.05514  ? 221 ASN A H    1 
ATOM   3181 H HA   . ASN A 1 207 ? 1.43853   -1.76779  16.85729  1.000 15.74990  ? 221 ASN A HA   1 
ATOM   3182 H HB2  . ASN A 1 207 ? 2.76221   0.12539   17.64427  1.000 16.40888  ? 221 ASN A HB2  1 
ATOM   3183 H HB3  . ASN A 1 207 ? 1.98047   1.00403   16.57549  1.000 16.40888  ? 221 ASN A HB3  1 
ATOM   3184 H HD21 . ASN A 1 207 ? 0.06651   1.94819   19.09924  0.119 18.81858  ? 221 ASN A HD21 1 
ATOM   3185 H HD22 . ASN A 1 207 ? 1.17765   2.35567   18.19472  1.000 18.81858  ? 221 ASN A HD22 1 
ATOM   3186 N N    . ASN A 1 208 ? -0.42002  -1.67797  15.31331  1.000 14.02736  ? 222 ASN A N    1 
ATOM   3187 C CA   . ASN A 1 208 ? -1.47959  -1.69400  14.30560  1.000 14.54835  ? 222 ASN A CA   1 
ATOM   3188 C C    . ASN A 1 208 ? -2.81474  -1.25728  14.91182  1.000 15.28399  ? 222 ASN A C    1 
ATOM   3189 O O    . ASN A 1 208 ? -3.29993  -1.86127  15.86981  1.000 16.29503  ? 222 ASN A O    1 
ATOM   3190 C CB   . ASN A 1 208 ? -1.61776  -3.09263  13.70324  1.000 15.22096  ? 222 ASN A CB   1 
ATOM   3191 C CG   . ASN A 1 208 ? -0.28649  -3.70412  13.32883  1.000 15.45469  ? 222 ASN A CG   1 
ATOM   3192 O OD1  . ASN A 1 208 ? 0.05256   -4.79112  13.79453  1.000 15.04059  ? 222 ASN A OD1  1 
ATOM   3193 N ND2  . ASN A 1 208 ? 0.47034   -3.01477  12.48969  1.000 17.08918  ? 222 ASN A ND2  1 
ATOM   3194 H H    . ASN A 1 208 ? -0.49805  -2.30061  15.90138  1.000 16.82772  ? 222 ASN A H    1 
ATOM   3195 H HA   . ASN A 1 208 ? -1.25150  -1.05379  13.61350  1.000 17.45291  ? 222 ASN A HA   1 
ATOM   3196 H HB2  . ASN A 1 208 ? -2.04332  -3.67515  14.35167  1.000 18.26004  ? 222 ASN A HB2  1 
ATOM   3197 H HB3  . ASN A 1 208 ? -2.15914  -3.03859  12.90019  1.000 18.26004  ? 222 ASN A HB3  1 
ATOM   3198 H HD21 . ASN A 1 208 ? 0.19646   -2.25830  12.18582  0.691 20.50191  ? 222 ASN A HD21 1 
ATOM   3199 H HD22 . ASN A 1 208 ? 1.23593   -3.32337  12.24836  1.000 20.50191  ? 222 ASN A HD22 1 
ATOM   3200 N N    . ASN A 1 209 ? -3.41135  -0.21546  14.34221  1.000 16.01726  ? 223 ASN A N    1 
ATOM   3201 C CA   . ASN A 1 209 ? -4.75707  0.22771   14.69061  1.000 18.02911  ? 223 ASN A CA   1 
ATOM   3202 C C    . ASN A 1 209 ? -4.98772  0.45392   16.18847  1.000 18.10741  ? 223 ASN A C    1 
ATOM   3203 O O    . ASN A 1 209 ? -6.00577  0.02336   16.73470  1.000 19.19791  ? 223 ASN A O    1 
ATOM   3204 C CB   . ASN A 1 209 ? -5.79355  -0.74049  14.13951  1.000 20.73897  ? 223 ASN A CB   1 
ATOM   3205 C CG   . ASN A 1 209 ? -5.61789  -0.98629  12.66614  1.000 23.26955  ? 223 ASN A CG   1 
ATOM   3206 O OD1  . ASN A 1 209 ? -5.53001  -0.04575  11.88014  1.000 25.40790  ? 223 ASN A OD1  1 
ATOM   3207 N ND2  . ASN A 1 209 ? -5.53840  -2.25125  12.28152  1.000 25.20266  ? 223 ASN A ND2  1 
ATOM   3208 H H    . ASN A 1 209 ? -3.04449  0.26603   13.73133  1.000 19.21561  ? 223 ASN A H    1 
ATOM   3209 H HA   . ASN A 1 209 ? -4.88413  1.09729   14.28002  1.000 21.62983  ? 223 ASN A HA   1 
ATOM   3210 H HB2  . ASN A 1 209 ? -5.71076  -1.59051  14.59941  1.000 24.88165  ? 223 ASN A HB2  1 
ATOM   3211 H HB3  . ASN A 1 209 ? -6.67961  -0.37187  14.28060  1.000 24.88165  ? 223 ASN A HB3  1 
ATOM   3212 H HD21 . ASN A 1 209 ? -5.58749  -2.88178  12.86429  0.055 30.23808  ? 223 ASN A HD21 1 
ATOM   3213 H HD22 . ASN A 1 209 ? -5.43770  -2.44204  11.44902  1.000 30.23808  ? 223 ASN A HD22 1 
ATOM   3214 N N    . PRO A 1 210 ? -4.09682  1.16769   16.86780  1.000 16.82783  ? 224 PRO A N    1 
ATOM   3215 C CA   . PRO A 1 210 ? -4.35365  1.49220   18.27285  1.000 17.64768  ? 224 PRO A CA   1 
ATOM   3216 C C    . PRO A 1 210 ? -5.52888  2.44223   18.37699  1.000 19.13441  ? 224 PRO A C    1 
ATOM   3217 O O    . PRO A 1 210 ? -5.85452  3.17924   17.44450  1.000 19.97439  ? 224 PRO A O    1 
ATOM   3218 C CB   . PRO A 1 210 ? -3.06993  2.18851   18.71862  1.000 16.79404  ? 224 PRO A CB   1 
ATOM   3219 C CG   . PRO A 1 210 ? -2.56174  2.81259   17.46501  1.000 16.70788  ? 224 PRO A CG   1 
ATOM   3220 C CD   . PRO A 1 210 ? -2.85875  1.80192   16.38531  1.000 16.95991  ? 224 PRO A CD   1 
ATOM   3221 H HA   . PRO A 1 210 ? -4.49775  0.69381   18.80456  1.000 21.17211  ? 224 PRO A HA   1 
ATOM   3222 H HB2  . PRO A 1 210 ? -3.26690  2.85865   19.39169  1.000 20.14775  ? 224 PRO A HB2  1 
ATOM   3223 H HB3  . PRO A 1 210 ? -2.44012  1.54008   19.07043  1.000 20.14775  ? 224 PRO A HB3  1 
ATOM   3224 H HG2  . PRO A 1 210 ? -3.02716  3.64701   17.29760  1.000 20.04435  ? 224 PRO A HG2  1 
ATOM   3225 H HG3  . PRO A 1 210 ? -1.60794  2.97350   17.53764  1.000 20.04435  ? 224 PRO A HG3  1 
ATOM   3226 H HD2  . PRO A 1 210 ? -3.00190  2.23812   15.53083  0.826 20.34679  ? 224 PRO A HD2  1 
ATOM   3227 H HD3  . PRO A 1 210 ? -2.14202  1.15262   16.31039  1.000 20.34679  ? 224 PRO A HD3  1 
ATOM   3228 N N    . THR A 1 211 ? -6.16613  2.42130   19.53879  1.000 21.36793  ? 225 THR A N    1 
ATOM   3229 C CA   . THR A 1 211 ? -7.25973  3.33919   19.81548  1.000 22.78585  ? 225 THR A CA   1 
ATOM   3230 C C    . THR A 1 211 ? -6.80692  4.55605   20.60271  1.000 23.58499  ? 225 THR A C    1 
ATOM   3231 O O    . THR A 1 211 ? -7.61996  5.43792   20.87560  1.000 25.17708  ? 225 THR A O    1 
ATOM   3232 C CB   . THR A 1 211 ? -8.40491  2.63237   20.54784  1.000 25.09036  ? 225 THR A CB   1 
ATOM   3233 O OG1  . THR A 1 211 ? -7.90340  1.98861   21.72210  1.000 26.60565  ? 225 THR A OG1  1 
ATOM   3234 C CG2  . THR A 1 211 ? -9.06706  1.60457   19.64445  1.000 25.21063  ? 225 THR A CG2  1 
ATOM   3235 H H    . THR A 1 211 ? -5.98263  1.88311   20.18399  1.000 25.63641  ? 225 THR A H    1 
ATOM   3236 H HA   . THR A 1 211 ? -7.62263  3.64517   18.96957  1.000 27.33791  ? 225 THR A HA   1 
ATOM   3237 H HB   . THR A 1 211 ? -9.07490  3.28553   20.80358  1.000 30.10332  ? 225 THR A HB   1 
ATOM   3238 H HG1  . THR A 1 211 ? -7.38300  1.36501   21.50783  1.000 31.92167  ? 225 THR A HG1  1 
ATOM   3239 H HG21 . THR A 1 211 ? -9.73623  1.10830   20.14127  0.009 30.24765  ? 225 THR A HG21 1 
ATOM   3240 H HG22 . THR A 1 211 ? -9.49553  2.04804   18.89569  0.020 30.24765  ? 225 THR A HG22 1 
ATOM   3241 H HG23 . THR A 1 211 ? -8.40292  0.98444   19.30493  0.120 30.24765  ? 225 THR A HG23 1 
ATOM   3242 N N    . SER A 1 212 ? -5.53627  4.61154   20.98333  1.000 23.10168  ? 226 SER A N    1 
ATOM   3243 C CA   . SER A 1 212 ? -4.91978  5.78786   21.57078  1.000 23.97964  ? 226 SER A CA   1 
ATOM   3244 C C    . SER A 1 212 ? -3.57285  5.96367   20.89531  1.000 22.58411  ? 226 SER A C    1 
ATOM   3245 O O    . SER A 1 212 ? -2.83193  4.99196   20.73349  1.000 22.43046  ? 226 SER A O    1 
ATOM   3246 C CB   . SER A 1 212 ? -4.69601  5.58982   23.06859  1.000 26.06238  ? 226 SER A CB   1 
ATOM   3247 O OG   . SER A 1 212 ? -3.82878  6.58562   23.57852  1.000 27.50210  ? 226 SER A OG   1 
ATOM   3248 H H    . SER A 1 212 ? -4.98991  3.95175   20.90742  1.000 27.71691  ? 226 SER A H    1 
ATOM   3249 H HA   . SER A 1 212 ? -5.47539  6.57145   21.43595  1.000 28.77046  ? 226 SER A HA   1 
ATOM   3250 H HB2  . SER A 1 212 ? -5.54905  5.64790   23.52668  0.438 31.26974  ? 226 SER A HB2  1 
ATOM   3251 H HB3  . SER A 1 212 ? -4.29854  4.71750   23.21684  1.000 31.26974  ? 226 SER A HB3  1 
ATOM   3252 H HG   . SER A 1 212 ? -3.03655  6.41871   23.35466  1.000 32.99741  ? 226 SER A HG   1 
ATOM   3253 N N    . GLU A 1 213 ? -3.25621  7.19285   20.49765  1.000 22.23516  ? 227 GLU A N    1 
ATOM   3254 C CA   . GLU A 1 213 ? -1.97925  7.45800   19.84696  1.000 22.99570  ? 227 GLU A CA   1 
ATOM   3255 C C    . GLU A 1 213 ? -0.81894  7.48236   20.82342  1.000 23.03394  ? 227 GLU A C    1 
ATOM   3256 O O    . GLU A 1 213 ? 0.33210   7.36121   20.39644  1.000 23.08740  ? 227 GLU A O    1 
ATOM   3257 C CB   . GLU A 1 213 ? -2.02825  8.79440   19.10541  1.000 24.55746  ? 227 GLU A CB   1 
ATOM   3258 C CG   . GLU A 1 213 ? -2.93972  8.78266   17.91085  1.000 24.94677  ? 227 GLU A CG   1 
ATOM   3259 C CD   . GLU A 1 213 ? -2.56358  7.70145   16.92604  1.000 26.02137  ? 227 GLU A CD   1 
ATOM   3260 O OE1  . GLU A 1 213 ? -1.36782  7.60731   16.56663  1.000 25.28538  ? 227 GLU A OE1  1 
ATOM   3261 O OE2  . GLU A 1 213 ? -3.46174  6.92642   16.53021  1.000 28.35703  ? 227 GLU A OE2  1 
ATOM   3262 H H    . GLU A 1 213 ? -3.75938  7.88381   20.59249  1.000 26.67708  ? 227 GLU A H    1 
ATOM   3263 H HA   . GLU A 1 213 ? -1.81873  6.75513   19.19803  1.000 27.58973  ? 227 GLU A HA   1 
ATOM   3264 H HB2  . GLU A 1 213 ? -2.34557  9.47903   19.71491  1.000 29.46385  ? 227 GLU A HB2  1 
ATOM   3265 H HB3  . GLU A 1 213 ? -1.13539  9.01356   18.79609  1.000 29.46385  ? 227 GLU A HB3  1 
ATOM   3266 H HG2  . GLU A 1 213 ? -3.84991  8.62194   18.20515  1.000 29.93101  ? 227 GLU A HG2  1 
ATOM   3267 H HG3  . GLU A 1 213 ? -2.88374  9.63862   17.45796  1.000 29.93101  ? 227 GLU A HG3  1 
ATOM   3268 N N    . SER A 1 214 ? -1.08659  7.62992   22.11282  1.000 23.36944  ? 228 SER A N    1 
ATOM   3269 C CA   . SER A 1 214 ? -0.02557  7.67750   23.10174  1.000 23.53005  ? 228 SER A CA   1 
ATOM   3270 C C    . SER A 1 214 ? 0.20978   6.34450   23.79824  1.000 22.40841  ? 228 SER A C    1 
ATOM   3271 O O    . SER A 1 214 ? 1.20287   6.21311   24.51364  1.000 23.54627  ? 228 SER A O    1 
ATOM   3272 C CB   . SER A 1 214 ? -0.34275  8.74520   24.14592  1.000 25.68396  ? 228 SER A CB   1 
ATOM   3273 O OG   . SER A 1 214 ? -1.63280  8.53319   24.67911  1.000 27.26629  ? 228 SER A OG   1 
ATOM   3274 H H    . SER A 1 214 ? -1.87866  7.70480   22.43932  1.000 28.03821  ? 228 SER A H    1 
ATOM   3275 H HA   . SER A 1 214 ? 0.80236   7.92268   22.65979  1.000 28.23095  ? 228 SER A HA   1 
ATOM   3276 H HB2  . SER A 1 214 ? 0.31019   8.69529   24.86151  1.000 30.81564  ? 228 SER A HB2  1 
ATOM   3277 H HB3  . SER A 1 214 ? -0.31037  9.61980   23.72767  1.000 30.81564  ? 228 SER A HB3  1 
ATOM   3278 H HG   . SER A 1 214 ? -2.21300  8.65233   24.08348  1.000 32.71444  ? 228 SER A HG   1 
ATOM   3279 N N    . ALA A 1 215 ? -0.66545  5.36084   23.60599  1.000 20.57909  ? 229 ALA A N    1 
ATOM   3280 C CA   . ALA A 1 215 ? -0.49407  4.05671   24.23687  1.000 19.27597  ? 229 ALA A CA   1 
ATOM   3281 C C    . ALA A 1 215 ? 0.72514   3.34078   23.66400  1.000 17.81460  ? 229 ALA A C    1 
ATOM   3282 O O    . ALA A 1 215 ? 0.84489   3.16558   22.44805  1.000 17.99074  ? 229 ALA A O    1 
ATOM   3283 C CB   . ALA A 1 215 ? -1.74202  3.21156   24.00833  1.000 20.33699  ? 229 ALA A CB   1 
ATOM   3284 H H    . ALA A 1 215 ? -1.36801  5.42329   23.11396  0.225 24.68980  ? 229 ALA A H    1 
ATOM   3285 H HA   . ALA A 1 215 ? -0.35828  4.17437   25.19008  1.000 23.12605  ? 229 ALA A HA   1 
ATOM   3286 H HB1  . ALA A 1 215 ? -2.51360  3.68823   24.35235  1.000 24.39928  ? 229 ALA A HB1  1 
ATOM   3287 H HB2  . ALA A 1 215 ? -1.84731  3.05467   23.05691  1.000 24.39928  ? 229 ALA A HB2  1 
ATOM   3288 H HB3  . ALA A 1 215 ? -1.64074  2.36653   24.47370  1.000 24.39928  ? 229 ALA A HB3  1 
ATOM   3289 N N    . THR A 1 216 ? 1.62591   2.90322   24.53858  1.000 16.89250  ? 230 THR A N    1 
ATOM   3290 C CA   . THR A 1 216 ? 2.90950   2.35071   24.11012  1.000 16.06262  ? 230 THR A CA   1 
ATOM   3291 C C    . THR A 1 216 ? 2.87693   0.82126   24.10258  1.000 15.18968  ? 230 THR A C    1 
ATOM   3292 O O    . THR A 1 216 ? 2.75338   0.18415   25.15396  1.000 16.61530  ? 230 THR A O    1 
ATOM   3293 C CB   . THR A 1 216 ? 4.03719   2.87352   24.99467  1.000 16.65056  ? 230 THR A CB   1 
ATOM   3294 O OG1  . THR A 1 216 ? 4.05612   4.30138   24.93016  1.000 19.23436  ? 230 THR A OG1  1 
ATOM   3295 C CG2  . THR A 1 216 ? 5.37915   2.34367   24.53066  1.000 17.03710  ? 230 THR A CG2  1 
ATOM   3296 H H    . THR A 1 216 ? 1.51648   2.91571   25.39150  0.949 20.26589  ? 230 THR A H    1 
ATOM   3297 H HA   . THR A 1 216 ? 3.06164   2.62752   23.19299  0.543 19.27004  ? 230 THR A HA   1 
ATOM   3298 H HB   . THR A 1 216 ? 3.89381   2.57985   25.90796  0.677 19.97557  ? 230 THR A HB   1 
ATOM   3299 H HG1  . THR A 1 216 ? 4.21843   4.55135   24.14481  1.000 23.07612  ? 230 THR A HG1  1 
ATOM   3300 H HG21 . THR A 1 216 ? 6.09642   2.82257   24.97461  1.000 20.43942  ? 230 THR A HG21 1 
ATOM   3301 H HG22 . THR A 1 216 ? 5.45373   1.39963   24.74073  0.676 20.43942  ? 230 THR A HG22 1 
ATOM   3302 H HG23 . THR A 1 216 ? 5.46860   2.46085   23.57193  1.000 20.43942  ? 230 THR A HG23 1 
ATOM   3303 N N    . ALA A 1 217 ? 2.99979   0.23917   22.91077  1.000 13.85482  ? 231 ALA A N    1 
ATOM   3304 C CA   . ALA A 1 217 ? 3.20043   -1.19532  22.77107  1.000 13.00679  ? 231 ALA A CA   1 
ATOM   3305 C C    . ALA A 1 217 ? 4.58340   -1.56439  23.28258  1.000 12.83155  ? 231 ALA A C    1 
ATOM   3306 O O    . ALA A 1 217 ? 5.53487   -0.79486  23.14417  1.000 13.31320  ? 231 ALA A O    1 
ATOM   3307 C CB   . ALA A 1 217 ? 3.09145   -1.58527  21.29698  1.000 13.58666  ? 231 ALA A CB   1 
ATOM   3308 H H    . ALA A 1 217 ? 2.96987   0.65949   22.16107  0.429 16.62068  ? 231 ALA A H    1 
ATOM   3309 H HA   . ALA A 1 217 ? 2.53047   -1.68260  23.27567  0.363 15.60304  ? 231 ALA A HA   1 
ATOM   3310 H HB1  . ALA A 1 217 ? 3.76164   -1.09934  20.79139  1.000 16.29888  ? 231 ALA A HB1  1 
ATOM   3311 H HB2  . ALA A 1 217 ? 3.24008   -2.53996  21.21104  0.744 16.29888  ? 231 ALA A HB2  1 
ATOM   3312 H HB3  . ALA A 1 217 ? 2.20510   -1.35819  20.97493  1.000 16.29888  ? 231 ALA A HB3  1 
ATOM   3313 N N    . ARG A 1 218 ? 4.69772   -2.75636  23.87253  1.000 12.09636  ? 232 ARG A N    1 
ATOM   3314 C CA   . ARG A 1 218 ? 5.96083   -3.17442  24.47613  1.000 11.94885  ? 232 ARG A CA   1 
ATOM   3315 C C    . ARG A 1 218 ? 6.09345   -4.68205  24.32691  1.000 11.28735  ? 232 ARG A C    1 
ATOM   3316 O O    . ARG A 1 218 ? 5.21736   -5.43179  24.76233  1.000 12.47865  ? 232 ARG A O    1 
ATOM   3317 C CB   . ARG A 1 218 ? 6.00963   -2.77741  25.95511  1.000 13.04985  ? 232 ARG A CB   1 
ATOM   3318 C CG   . ARG A 1 218 ? 7.32526   -3.08470  26.65927  1.000 13.35563  ? 232 ARG A CG   1 
ATOM   3319 C CD   . ARG A 1 218 ? 7.40361   -2.40212  28.01611  1.000 15.04427  ? 232 ARG A CD   1 
ATOM   3320 N NE   . ARG A 1 218 ? 6.43915   -2.95603  28.95309  1.000 16.08456  ? 232 ARG A NE   1 
ATOM   3321 C CZ   . ARG A 1 218 ? 6.62641   -4.06690  29.64992  1.000 16.10473  ? 232 ARG A CZ   1 
ATOM   3322 N NH1  . ARG A 1 218 ? 7.76973   -4.72895  29.59685  1.000 15.56752  ? 232 ARG A NH1  1 
ATOM   3323 N NH2  . ARG A 1 218 ? 5.64202   -4.52562  30.41957  1.000 17.36739  ? 232 ARG A NH2  1 
ATOM   3324 H H    . ARG A 1 218 ? 4.06350   -3.33385  23.93468  1.000 14.51052  ? 232 ARG A H    1 
ATOM   3325 H HA   . ARG A 1 218 ? 6.70056   -2.75233  24.01188  1.000 14.33351  ? 232 ARG A HA   1 
ATOM   3326 H HB2  . ARG A 1 218 ? 5.86014   -1.82132  26.02169  1.000 15.65471  ? 232 ARG A HB2  1 
ATOM   3327 H HB3  . ARG A 1 218 ? 5.30909   -3.25626  26.42506  1.000 15.65471  ? 232 ARG A HB3  1 
ATOM   3328 H HG2  . ARG A 1 218 ? 7.40123   -4.04218  26.79479  0.800 16.02165  ? 232 ARG A HG2  1 
ATOM   3329 H HG3  . ARG A 1 218 ? 8.06280   -2.76710  26.11515  1.000 16.02165  ? 232 ARG A HG3  1 
ATOM   3330 H HD2  . ARG A 1 218 ? 8.29198   -2.52500  28.38569  0.972 18.04802  ? 232 ARG A HD2  1 
ATOM   3331 H HD3  . ARG A 1 218 ? 7.21625   -1.45630  27.91019  1.000 18.04802  ? 232 ARG A HD3  1 
ATOM   3332 H HE   . ARG A 1 218 ? 5.69769   -2.53418  29.06205  0.473 19.29636  ? 232 ARG A HE   1 
ATOM   3333 H HH11 . ARG A 1 218 ? 8.41131   -4.44013  29.10232  0.288 18.67592  ? 232 ARG A HH11 1 
ATOM   3334 H HH12 . ARG A 1 218 ? 7.87179   -5.44838  30.05686  1.000 18.67592  ? 232 ARG A HH12 1 
ATOM   3335 H HH21 . ARG A 1 218 ? 4.89488   -4.10168  30.46032  0.468 20.83575  ? 232 ARG A HH21 1 
ATOM   3336 H HH22 . ARG A 1 218 ? 5.75315   -5.24593  30.87608  1.000 20.83575  ? 232 ARG A HH22 1 
ATOM   3337 N N    . ILE A 1 219 ? 7.19858   -5.12839  23.72844  1.000 10.67754  ? 233 ILE A N    1 
ATOM   3338 C CA   . ILE A 1 219 ? 7.41924   -6.53492  23.41244  1.000 10.52418  ? 233 ILE A CA   1 
ATOM   3339 C C    . ILE A 1 219 ? 8.85217   -6.87656  23.78074  1.000 10.54848  ? 233 ILE A C    1 
ATOM   3340 O O    . ILE A 1 219 ? 9.77068   -6.12247  23.45505  1.000 11.38777  ? 233 ILE A O    1 
ATOM   3341 C CB   . ILE A 1 219 ? 7.21712   -6.80862  21.90143  1.000 10.72584  ? 233 ILE A CB   1 
ATOM   3342 C CG1  . ILE A 1 219 ? 5.83100   -6.36385  21.41277  1.000 11.62540  ? 233 ILE A CG1  1 
ATOM   3343 C CG2  . ILE A 1 219 ? 7.44282   -8.28339  21.59187  1.000 11.17114  ? 233 ILE A CG2  1 
ATOM   3344 C CD1  . ILE A 1 219 ? 4.65947   -7.15465  21.95379  1.000 11.89193  ? 233 ILE A CD1  1 
ATOM   3345 H H    . ILE A 1 219 ? 7.85030   -4.62016  23.49058  1.000 12.80793  ? 233 ILE A H    1 
ATOM   3346 H HA   . ILE A 1 219 ? 6.80337   -7.07825  23.92857  1.000 12.62391  ? 233 ILE A HA   1 
ATOM   3347 H HB   . ILE A 1 219 ? 7.87514   -6.27825  21.42539  1.000 12.86591  ? 233 ILE A HB   1 
ATOM   3348 H HG12 . ILE A 1 219 ? 5.69874   -5.43894  21.67344  1.000 13.94537  ? 233 ILE A HG12 1 
ATOM   3349 H HG13 . ILE A 1 219 ? 5.80938   -6.44247  20.44620  1.000 13.94537  ? 233 ILE A HG13 1 
ATOM   3350 H HG21 . ILE A 1 219 ? 6.90623   -8.81883  22.19707  1.000 13.40027  ? 233 ILE A HG21 1 
ATOM   3351 H HG22 . ILE A 1 219 ? 7.17979   -8.45738  20.67457  1.000 13.40027  ? 233 ILE A HG22 1 
ATOM   3352 H HG23 . ILE A 1 219 ? 8.38278   -8.49093  21.71149  1.000 13.40027  ? 233 ILE A HG23 1 
ATOM   3353 H HD11 . ILE A 1 219 ? 4.74189   -8.07753  21.66674  1.000 14.26520  ? 233 ILE A HD11 1 
ATOM   3354 H HD12 . ILE A 1 219 ? 4.66718   -7.10764  22.92262  0.933 14.26520  ? 233 ILE A HD12 1 
ATOM   3355 H HD13 . ILE A 1 219 ? 3.83598   -6.77381  21.61069  0.662 14.26520  ? 233 ILE A HD13 1 
ATOM   3356 N N    . LYS A 1 220 ? 9.05236   -8.02816  24.42757  1.000 10.32776  ? 234 LYS A N    1 
ATOM   3357 C CA   . LYS A 1 220 ? 10.36316  -8.45288  24.90340  1.000 11.50301  ? 234 LYS A CA   1 
ATOM   3358 C C    . LYS A 1 220 ? 10.78544  -9.71386  24.17015  1.000 11.25004  ? 234 LYS A C    1 
ATOM   3359 O O    . LYS A 1 220 ? 10.02157  -10.67658 24.09677  1.000 13.71282  ? 234 LYS A O    1 
ATOM   3360 C CB   . LYS A 1 220 ? 10.32616  -8.71593  26.42502  1.000 12.60498  ? 234 LYS A CB   1 
ATOM   3361 C CG   . LYS A 1 220 ? 9.89290   -7.52044  27.21958  1.000 13.92291  ? 234 LYS A CG   1 
ATOM   3362 C CD   . LYS A 1 220 ? 10.39205  -7.59380  28.66680  1.000 14.75666  ? 234 LYS A CD   1 
ATOM   3363 C CE   . LYS A 1 220 ? 9.90486   -8.82526  29.42031  1.000 15.27894  ? 234 LYS A CE   1 
ATOM   3364 N NZ   . LYS A 1 220 ? 10.16091  -8.69443  30.88533  1.000 15.08450  ? 234 LYS A NZ   1 
ATOM   3365 H H    . LYS A 1 220 ? 8.42635   -8.59062  24.60465  1.000 12.38820  ? 234 LYS A H    1 
ATOM   3366 H HA   . LYS A 1 220 ? 11.01734  -7.76125  24.71739  0.951 13.79851  ? 234 LYS A HA   1 
ATOM   3367 H HB2  . LYS A 1 220 ? 9.70152   -9.43607  26.60422  1.000 15.12087  ? 234 LYS A HB2  1 
ATOM   3368 H HB3  . LYS A 1 220 ? 11.21497  -8.96603  26.72228  1.000 15.12087  ? 234 LYS A HB3  1 
ATOM   3369 H HG2  . LYS A 1 220 ? 10.25405  -6.71705  26.81334  0.499 16.70238  ? 234 LYS A HG2  1 
ATOM   3370 H HG3  . LYS A 1 220 ? 8.92392   -7.47836  27.23351  0.803 16.70238  ? 234 LYS A HG3  1 
ATOM   3371 H HD2  . LYS A 1 220 ? 11.36182  -7.61418  28.66275  1.000 17.70289  ? 234 LYS A HD2  1 
ATOM   3372 H HD3  . LYS A 1 220 ? 10.07867  -6.81083  29.14603  1.000 17.70289  ? 234 LYS A HD3  1 
ATOM   3373 H HE2  . LYS A 1 220 ? 8.95028   -8.93043  29.28387  0.946 18.32961  ? 234 LYS A HE2  1 
ATOM   3374 H HE3  . LYS A 1 220 ? 10.37477  -9.60923  29.09553  1.000 18.32961  ? 234 LYS A HE3  1 
ATOM   3375 H HZ1  . LYS A 1 220 ? 9.69535   -8.01174  31.21593  1.000 18.09629  ? 234 LYS A HZ1  1 
ATOM   3376 H HZ2  . LYS A 1 220 ? 9.91693   -9.44049  31.30480  1.000 18.09629  ? 234 LYS A HZ2  1 
ATOM   3377 H HZ3  . LYS A 1 220 ? 11.02705  -8.55101  31.03134  1.000 18.09629  ? 234 LYS A HZ3  1 
ATOM   3378 N N    . PHE A 1 221 ? 12.01370  -9.74086  23.67816  1.000 9.99190   ? 235 PHE A N    1 
ATOM   3379 C CA   . PHE A 1 221 ? 12.57509  -10.92925 23.04992  1.000 10.36285  ? 235 PHE A CA   1 
ATOM   3380 C C    . PHE A 1 221 ? 13.65230  -11.49806 23.96196  1.000 10.71060  ? 235 PHE A C    1 
ATOM   3381 O O    . PHE A 1 221 ? 14.59864  -10.79073 24.33745  1.000 11.85942  ? 235 PHE A O    1 
ATOM   3382 C CB   . PHE A 1 221 ? 13.18296  -10.60934 21.68921  1.000 10.53186  ? 235 PHE A CB   1 
ATOM   3383 C CG   . PHE A 1 221 ? 12.16163  -10.42993 20.59828  1.000 10.41773  ? 235 PHE A CG   1 
ATOM   3384 C CD1  . PHE A 1 221 ? 11.34417  -9.31119  20.56069  1.000 10.90899  ? 235 PHE A CD1  1 
ATOM   3385 C CD2  . PHE A 1 221 ? 12.03628  -11.38203 19.60486  1.000 11.03188  ? 235 PHE A CD2  1 
ATOM   3386 C CE1  . PHE A 1 221 ? 10.39785  -9.17199  19.56189  1.000 11.53343  ? 235 PHE A CE1  1 
ATOM   3387 C CE2  . PHE A 1 221 ? 11.10709  -11.23278 18.60927  1.000 10.74507  ? 235 PHE A CE2  1 
ATOM   3388 C CZ   . PHE A 1 221 ? 10.30463  -10.12211 18.57887  1.000 11.08736  ? 235 PHE A CZ   1 
ATOM   3389 H H    . PHE A 1 221 ? 12.55263  -9.07090  23.69614  1.000 11.98517  ? 235 PHE A H    1 
ATOM   3390 H HA   . PHE A 1 221 ? 11.86872  -11.58319 22.93036  1.000 12.43031  ? 235 PHE A HA   1 
ATOM   3391 H HB2  . PHE A 1 221 ? 13.68949  -9.78509  21.75953  1.000 12.63313  ? 235 PHE A HB2  1 
ATOM   3392 H HB3  . PHE A 1 221 ? 13.76881  -11.33767 21.42994  1.000 12.63313  ? 235 PHE A HB3  1 
ATOM   3393 H HD1  . PHE A 1 221 ? 11.43247  -8.65127  21.21000  1.000 13.08568  ? 235 PHE A HD1  1 
ATOM   3394 H HD2  . PHE A 1 221 ? 12.58765  -12.13093 19.61211  1.000 13.23315  ? 235 PHE A HD2  1 
ATOM   3395 H HE1  . PHE A 1 221 ? 9.82764   -8.43732  19.55739  1.000 13.83501  ? 235 PHE A HE1  1 
ATOM   3396 H HE2  . PHE A 1 221 ? 11.02070  -11.88610 17.95306  1.000 12.88897  ? 235 PHE A HE2  1 
ATOM   3397 H HZ   . PHE A 1 221 ? 9.69308   -10.01262 17.88683  1.000 13.29972  ? 235 PHE A HZ   1 
ATOM   3398 N N    . ALA A 1 222 ? 13.52158  -12.77063 24.31829  1.000 11.10626  ? 236 ALA A N    1 
ATOM   3399 C CA   . ALA A 1 222 ? 14.60281  -13.49665 24.97893  1.000 10.91724  ? 236 ALA A CA   1 
ATOM   3400 C C    . ALA A 1 222 ? 15.58920  -14.09719 23.98947  1.000 11.17049  ? 236 ALA A C    1 
ATOM   3401 O O    . ALA A 1 222 ? 16.72305  -14.40414 24.36369  1.000 11.90706  ? 236 ALA A O    1 
ATOM   3402 C CB   . ALA A 1 222 ? 14.02548  -14.61300 25.85190  1.000 12.19175  ? 236 ALA A CB   1 
ATOM   3403 H H    . ALA A 1 222 ? 12.81287  -13.24016 24.18842  0.764 13.32241  ? 236 ALA A H    1 
ATOM   3404 H HA   . ALA A 1 222 ? 15.08766  -12.88697 25.55695  1.000 13.09558  ? 236 ALA A HA   1 
ATOM   3405 H HB1  . ALA A 1 222 ? 14.75532  -15.13309 26.22305  0.457 14.62499  ? 236 ALA A HB1  1 
ATOM   3406 H HB2  . ALA A 1 222 ? 13.50430  -14.21669 26.56759  1.000 14.62499  ? 236 ALA A HB2  1 
ATOM   3407 H HB3  . ALA A 1 222 ? 13.45939  -15.18038 25.30553  1.000 14.62499  ? 236 ALA A HB3  1 
ATOM   3408 N N    . ALA A 1 223 ? 15.18560  -14.25440 22.73609  1.000 11.23926  ? 237 ALA A N    1 
ATOM   3409 C CA   . ALA A 1 223 ? 16.03031  -14.79993 21.68918  1.000 11.38771  ? 237 ALA A CA   1 
ATOM   3410 C C    . ALA A 1 223 ? 15.44939  -14.35508 20.36041  1.000 10.31674  ? 237 ALA A C    1 
ATOM   3411 O O    . ALA A 1 223 ? 14.23131  -14.21986 20.22068  1.000 10.38347  ? 237 ALA A O    1 
ATOM   3412 C CB   . ALA A 1 223 ? 16.07663  -16.32683 21.73403  1.000 11.89651  ? 237 ALA A CB   1 
ATOM   3413 H H    . ALA A 1 223 ? 14.39906  -14.04485 22.45852  1.000 13.48200  ? 237 ALA A H    1 
ATOM   3414 H HA   . ALA A 1 223 ? 16.93487  -14.46413 21.78872  1.000 13.66015  ? 237 ALA A HA   1 
ATOM   3415 H HB1  . ALA A 1 223 ? 16.37099  -16.60813 22.61445  0.786 14.27070  ? 237 ALA A HB1  1 
ATOM   3416 H HB2  . ALA A 1 223 ? 15.18918  -16.67510 21.55503  1.000 14.27070  ? 237 ALA A HB2  1 
ATOM   3417 H HB3  . ALA A 1 223 ? 16.69845  -16.64384 21.06042  1.000 14.27070  ? 237 ALA A HB3  1 
ATOM   3418 N N    . LEU A 1 224 ? 16.32066  -14.16089 19.38051  1.000 11.03989  ? 238 LEU A N    1 
ATOM   3419 C CA   . LEU A 1 224 ? 15.90162  -13.90100 18.00617  1.000 10.72732  ? 238 LEU A CA   1 
ATOM   3420 C C    . LEU A 1 224 ? 17.06293  -14.23318 17.09138  1.000 11.39494  ? 238 LEU A C    1 
ATOM   3421 O O    . LEU A 1 224 ? 18.18093  -13.78348 17.33551  1.000 11.86838  ? 238 LEU A O    1 
ATOM   3422 C CB   . LEU A 1 224 ? 15.53065  -12.43455 17.81600  1.000 11.02888  ? 238 LEU A CB   1 
ATOM   3423 C CG   . LEU A 1 224 ? 15.14981  -12.06477 16.38030  1.000 11.26639  ? 238 LEU A CG   1 
ATOM   3424 C CD1  . LEU A 1 224 ? 13.86141  -12.71592 15.93608  1.000 11.67926  ? 238 LEU A CD1  1 
ATOM   3425 C CD2  . LEU A 1 224 ? 15.05519  -10.57175 16.23344  1.000 11.89666  ? 238 LEU A CD2  1 
ATOM   3426 H H    . LEU A 1 224 ? 17.17424  -14.17433 19.48460  1.000 13.24276  ? 238 LEU A H    1 
ATOM   3427 H HA   . LEU A 1 224 ? 15.13670  -14.45671 17.78940  1.000 12.86768  ? 238 LEU A HA   1 
ATOM   3428 H HB2  . LEU A 1 224 ? 14.77124  -12.23126 18.38422  1.000 13.22955  ? 238 LEU A HB2  1 
ATOM   3429 H HB3  . LEU A 1 224 ? 16.29060  -11.88771 18.06967  1.000 13.22955  ? 238 LEU A HB3  1 
ATOM   3430 H HG   . LEU A 1 224 ? 15.84838  -12.39910 15.79624  1.000 13.51456  ? 238 LEU A HG   1 
ATOM   3431 H HD11 . LEU A 1 224 ? 13.69705  -12.48961 15.00728  1.000 14.01001  ? 238 LEU A HD11 1 
ATOM   3432 H HD12 . LEU A 1 224 ? 13.94392  -13.67758 16.03261  1.000 14.01001  ? 238 LEU A HD12 1 
ATOM   3433 H HD13 . LEU A 1 224 ? 13.13510  -12.38902 16.48971  1.000 14.01001  ? 238 LEU A HD13 1 
ATOM   3434 H HD21 . LEU A 1 224 ? 15.92770  -10.18210 16.40015  0.288 14.27089  ? 238 LEU A HD21 1 
ATOM   3435 H HD22 . LEU A 1 224 ? 14.76548  -10.36082 15.33207  1.000 14.27089  ? 238 LEU A HD22 1 
ATOM   3436 H HD23 . LEU A 1 224 ? 14.41274  -10.23135 16.87555  1.000 14.27089  ? 238 LEU A HD23 1 
ATOM   3437 N N    . ALA A 1 225 ? 16.79871  -14.97707 16.02608  1.000 11.98940  ? 239 ALA A N    1 
ATOM   3438 C CA   . ALA A 1 225 ? 17.82576  -15.26373 15.03992  1.000 12.67826  ? 239 ALA A CA   1 
ATOM   3439 C C    . ALA A 1 225 ? 17.16464  -15.50653 13.70156  1.000 13.04495  ? 239 ALA A C    1 
ATOM   3440 O O    . ALA A 1 225 ? 16.03561  -15.99722 13.62346  1.000 13.47267  ? 239 ALA A O    1 
ATOM   3441 C CB   . ALA A 1 225 ? 18.62050  -16.51782 15.39445  1.000 13.82956  ? 239 ALA A CB   1 
ATOM   3442 H H    . ALA A 1 225 ? 16.03219  -15.32656 15.85313  1.000 14.38217  ? 239 ALA A H    1 
ATOM   3443 H HA   . ALA A 1 225 ? 18.42267  -14.50094 14.98739  1.000 15.20881  ? 239 ALA A HA   1 
ATOM   3444 H HB1  . ALA A 1 225 ? 19.07172  -16.37680 16.24146  1.000 16.59036  ? 239 ALA A HB1  1 
ATOM   3445 H HB2  . ALA A 1 225 ? 18.01051  -17.26865 15.46561  1.000 16.59036  ? 239 ALA A HB2  1 
ATOM   3446 H HB3  . ALA A 1 225 ? 19.27252  -16.68636 14.69635  1.000 16.59036  ? 239 ALA A HB3  1 
ATOM   3447 N N    A TRP A 1 226 ? 17.89710  -15.19256 12.64717  0.902 13.16485  ? 240 TRP A N    1 
ATOM   3448 N N    B TRP A 1 226 ? 17.84086  -15.17055 12.61929  0.098 15.53946  ? 240 TRP A N    1 
ATOM   3449 C CA   A TRP A 1 226 ? 17.46325  -15.59736 11.32485  0.902 14.85280  ? 240 TRP A CA   1 
ATOM   3450 C CA   B TRP A 1 226 ? 17.39965  -15.72303 11.34916  0.098 18.08481  ? 240 TRP A CA   1 
ATOM   3451 C C    A TRP A 1 226 ? 18.61797  -16.22516 10.56598  0.902 18.32375  ? 240 TRP A C    1 
ATOM   3452 C C    B TRP A 1 226 ? 18.58828  -16.22978 10.56010  0.098 20.62887  ? 240 TRP A C    1 
ATOM   3453 O O    A TRP A 1 226 ? 19.76212  -15.80578 10.72345  0.902 19.51570  ? 240 TRP A O    1 
ATOM   3454 O O    B TRP A 1 226 ? 19.68979  -15.67743 10.61280  0.098 21.05410  ? 240 TRP A O    1 
ATOM   3455 C CB   A TRP A 1 226 ? 16.66499  -14.51610 10.56780  0.902 16.90277  ? 240 TRP A CB   1 
ATOM   3456 C CB   B TRP A 1 226 ? 16.49949  -14.82845 10.47484  0.098 17.99974  ? 240 TRP A CB   1 
ATOM   3457 C CG   A TRP A 1 226 ? 17.01746  -13.07613 10.71483  0.902 15.50573  ? 240 TRP A CG   1 
ATOM   3458 C CG   B TRP A 1 226 ? 15.96770  -13.59849 11.10069  0.098 17.32843  ? 240 TRP A CG   1 
ATOM   3459 C CD1  A TRP A 1 226 ? 18.19395  -12.47087 10.35411  0.902 15.08848  ? 240 TRP A CD1  1 
ATOM   3460 C CD1  B TRP A 1 226 ? 14.76884  -13.43169 11.72394  0.098 16.48837  ? 240 TRP A CD1  1 
ATOM   3461 C CD2  A TRP A 1 226 ? 16.15529  -12.02270 11.17726  0.902 13.32139  ? 240 TRP A CD2  1 
ATOM   3462 C CD2  B TRP A 1 226 ? 16.60708  -12.33666 11.11717  0.098 17.39760  ? 240 TRP A CD2  1 
ATOM   3463 N NE1  A TRP A 1 226 ? 18.11459  -11.12345 10.57462  0.902 14.72628  ? 240 TRP A NE1  1 
ATOM   3464 N NE1  B TRP A 1 226 ? 14.62860  -12.13153 12.14000  0.098 16.61875  ? 240 TRP A NE1  1 
ATOM   3465 C CE2  A TRP A 1 226 ? 16.87379  -10.82219 11.06319  0.902 12.56683  ? 240 TRP A CE2  1 
ATOM   3466 C CE2  B TRP A 1 226 ? 15.75296  -11.43776 11.78037  0.098 17.24820  ? 240 TRP A CE2  1 
ATOM   3467 C CE3  A TRP A 1 226 ? 14.83280  -11.97093 11.66343  0.902 13.90560  ? 240 TRP A CE3  1 
ATOM   3468 C CE3  B TRP A 1 226 ? 17.82935  -11.87906 10.64067  0.098 17.77800  ? 240 TRP A CE3  1 
ATOM   3469 C CZ2  A TRP A 1 226 ? 16.33554  -9.59857  11.41384  0.902 13.61632  ? 240 TRP A CZ2  1 
ATOM   3470 C CZ2  B TRP A 1 226 ? 16.08978  -10.10777 11.97732  0.098 17.83757  ? 240 TRP A CZ2  1 
ATOM   3471 C CZ3  A TRP A 1 226 ? 14.32712  -10.74802 12.02992  0.902 13.62433  ? 240 TRP A CZ3  1 
ATOM   3472 C CZ3  B TRP A 1 226 ? 18.15676  -10.58533 10.83283  0.098 17.81426  ? 240 TRP A CZ3  1 
ATOM   3473 C CH2  A TRP A 1 226 ? 15.05442  -9.58289  11.87846  0.902 14.23821  ? 240 TRP A CH2  1 
ATOM   3474 C CH2  B TRP A 1 226 ? 17.29721  -9.69920  11.49350  0.098 17.97742  ? 240 TRP A CH2  1 
ATOM   3475 H H    A TRP A 1 226 ? 18.63602  -14.75333 12.67313  0.902 15.79272  ? 240 TRP A H    1 
ATOM   3476 H H    B TRP A 1 226 ? 18.52506  -14.65011 12.59450  0.098 18.64225  ? 240 TRP A H    1 
ATOM   3477 H HA   A TRP A 1 226 ? 16.81040  -16.31120 11.39645  0.902 17.81825  ? 240 TRP A HA   1 
ATOM   3478 H HA   B TRP A 1 226 ? 16.82504  -16.47158 11.57365  0.098 21.69666  ? 240 TRP A HA   1 
ATOM   3479 H HB2  A TRP A 1 226 ? 16.74189  -14.71437 9.62140   0.902 20.27822  ? 240 TRP A HB2  1 
ATOM   3480 H HB2  B TRP A 1 226 ? 17.01385  -14.55156 9.70046   0.098 21.59458  ? 240 TRP A HB2  1 
ATOM   3481 H HB3  A TRP A 1 226 ? 15.73999  -14.59448 10.84909  0.902 20.27822  ? 240 TRP A HB3  1 
ATOM   3482 H HB3  B TRP A 1 226 ? 15.73516  -15.35566 10.19421  0.098 21.59458  ? 240 TRP A HB3  1 
ATOM   3483 H HD1  A TRP A 1 226 ? 18.93686  -12.91197 10.00999  0.902 18.10107  ? 240 TRP A HD1  1 
ATOM   3484 H HD1  B TRP A 1 226 ? 14.13643  -14.10191 11.84955  0.098 19.78093  ? 240 TRP A HD1  1 
ATOM   3485 H HE1  A TRP A 1 226 ? 18.74452  -10.55632 10.42918  0.902 17.66643  ? 240 TRP A HE1  1 
ATOM   3486 H HE1  B TRP A 1 226 ? 13.94943  -11.80733 12.55620  0.098 19.93739  ? 240 TRP A HE1  1 
ATOM   3487 H HE3  A TRP A 1 226 ? 14.31813  -12.74234 11.73383  0.902 16.68161  ? 240 TRP A HE3  1 
ATOM   3488 H HE3  B TRP A 1 226 ? 18.41058  -12.45419 10.19762  0.098 21.32849  ? 240 TRP A HE3  1 
ATOM   3489 H HZ2  A TRP A 1 226 ? 16.82950  -8.81449  11.33562  0.902 16.33447  ? 240 TRP A HZ2  1 
ATOM   3490 H HZ2  B TRP A 1 226 ? 15.51877  -9.52139  12.41892  0.098 21.39998  ? 240 TRP A HZ2  1 
ATOM   3491 H HZ3  A TRP A 1 226 ? 13.47097  -10.70265 12.39025  0.902 16.34409  ? 240 TRP A HZ3  1 
ATOM   3492 H HZ3  B TRP A 1 226 ? 18.97458  -10.27349 10.51846  0.098 21.37200  ? 240 TRP A HZ3  1 
ATOM   3493 H HH2  A TRP A 1 226 ? 14.66076  -8.76958  12.09856  0.902 17.08074  ? 240 TRP A HH2  1 
ATOM   3494 H HH2  B TRP A 1 226 ? 17.55550  -8.81274  11.60470  0.098 21.56780  ? 240 TRP A HH2  1 
ATOM   3495 N N    . VAL A 1 227 ? 18.32418  -17.30442 9.82627   1.000 22.66329  ? 241 VAL A N    1 
ATOM   3496 C CA   A VAL A 1 227 ? 19.35349  -18.14783 9.22960   0.669 26.49896  ? 241 VAL A CA   1 
ATOM   3497 C CA   B VAL A 1 227 ? 19.35604  -18.14477 9.22980   0.331 26.46120  ? 241 VAL A CA   1 
ATOM   3498 C C    . VAL A 1 227 ? 18.83208  -18.69597 7.90917   1.000 28.99844  ? 241 VAL A C    1 
ATOM   3499 O O    . VAL A 1 227 ? 17.62155  -18.73395 7.65510   1.000 27.71147  ? 241 VAL A O    1 
ATOM   3500 C CB   A VAL A 1 227 ? 19.74057  -19.30956 10.17364  0.669 28.49014  ? 241 VAL A CB   1 
ATOM   3501 C CB   B VAL A 1 227 ? 19.74128  -19.30641 10.17938  0.331 27.86948  ? 241 VAL A CB   1 
ATOM   3502 C CG1  A VAL A 1 227 ? 20.22447  -18.77100 11.51185  0.669 29.73105  ? 241 VAL A CG1  1 
ATOM   3503 C CG1  B VAL A 1 227 ? 20.92615  -20.09249 9.62235   0.331 27.72948  ? 241 VAL A CG1  1 
ATOM   3504 C CG2  A VAL A 1 227 ? 18.56352  -20.25079 10.37745  0.669 28.66770  ? 241 VAL A CG2  1 
ATOM   3505 C CG2  B VAL A 1 227 ? 20.04271  -18.77900 11.58118  0.331 28.82608  ? 241 VAL A CG2  1 
ATOM   3506 H H    . VAL A 1 227 ? 17.52279  -17.56674 9.65727   0.270 27.19084  ? 241 VAL A H    1 
ATOM   3507 H HA   . VAL A 1 227 ? 20.14133  -17.61375 9.04257   1.000 31.74833  ? 241 VAL A HA   1 
ATOM   3508 H HB   A VAL A 1 227 ? 20.46369  -19.81162 9.76629   0.669 34.18306  ? 241 VAL A HB   1 
ATOM   3509 H HB   B VAL A 1 227 ? 18.98936  -19.91553 10.24639  0.331 33.43826  ? 241 VAL A HB   1 
ATOM   3510 H HG11 A VAL A 1 227 ? 19.47072  -18.39307 11.99137  0.669 35.67215  ? 241 VAL A HG11 1 
ATOM   3511 H HG11 B VAL A 1 227 ? 21.43020  -19.52096 9.02220   0.331 33.27027  ? 241 VAL A HG11 1 
ATOM   3512 H HG12 A VAL A 1 227 ? 20.61111  -19.49849 12.02387  0.669 35.67215  ? 241 VAL A HG12 1 
ATOM   3513 H HG12 B VAL A 1 227 ? 21.48974  -20.37805 10.35837  0.331 33.27027  ? 241 VAL A HG12 1 
ATOM   3514 H HG13 A VAL A 1 227 ? 20.89288  -18.08611 11.35359  0.669 35.67215  ? 241 VAL A HG13 1 
ATOM   3515 H HG13 B VAL A 1 227 ? 20.59358  -20.86613 9.14092   0.331 33.27027  ? 241 VAL A HG13 1 
ATOM   3516 H HG21 A VAL A 1 227 ? 17.73844  -19.74873 10.28759  0.669 34.39613  ? 241 VAL A HG21 1 
ATOM   3517 H HG21 B VAL A 1 227 ? 20.50322  -17.92857 11.50637  0.331 34.58619  ? 241 VAL A HG21 1 
ATOM   3518 H HG22 A VAL A 1 227 ? 18.59934  -20.95099 9.70712   0.669 34.39613  ? 241 VAL A HG22 1 
ATOM   3519 H HG22 B VAL A 1 227 ? 19.20778  -18.66197 12.06086  0.331 34.58619  ? 241 VAL A HG22 1 
ATOM   3520 H HG23 A VAL A 1 227 ? 18.61955  -20.63901 11.26461  0.669 34.39613  ? 241 VAL A HG23 1 
ATOM   3521 H HG23 B VAL A 1 227 ? 20.60405  -19.41940 12.04560  0.331 34.58619  ? 241 VAL A HG23 1 
ATOM   3522 N N    . ASP A 1 228 ? 19.75989  -19.13933 7.06126   1.000 38.30045  ? 242 ASP A N    1 
ATOM   3523 C CA   . ASP A 1 228 ? 19.41797  -19.66271 5.74510   1.000 47.89956  ? 242 ASP A CA   1 
ATOM   3524 C C    . ASP A 1 228 ? 19.89406  -21.09067 5.49679   1.000 52.92492  ? 242 ASP A C    1 
ATOM   3525 O O    . ASP A 1 228 ? 19.65124  -21.62240 4.40694   1.000 53.59338  ? 242 ASP A O    1 
ATOM   3526 C CB   . ASP A 1 228 ? 19.96758  -18.73757 4.64972   1.000 52.03994  ? 242 ASP A CB   1 
ATOM   3527 C CG   . ASP A 1 228 ? 21.48710  -18.66066 4.65094   1.000 55.53625  ? 242 ASP A CG   1 
ATOM   3528 O OD1  . ASP A 1 228 ? 22.13768  -19.45687 5.36296   1.000 56.69315  ? 242 ASP A OD1  1 
ATOM   3529 O OD2  . ASP A 1 228 ? 22.03396  -17.79557 3.93484   1.000 57.12962  ? 242 ASP A OD2  1 
ATOM   3530 H H    . ASP A 1 228 ? 20.60318  -19.14624 7.22983   0.553 45.95543  ? 242 ASP A H    1 
ATOM   3531 H HA   . ASP A 1 228 ? 18.45087  -19.67520 5.67120   1.000 57.47436  ? 242 ASP A HA   1 
ATOM   3532 H HB2  . ASP A 1 228 ? 19.68496  -19.07067 3.78365   1.000 62.44283  ? 242 ASP A HB2  1 
ATOM   3533 H HB3  . ASP A 1 228 ? 19.62197  -17.84210 4.78967   1.000 62.44283  ? 242 ASP A HB3  1 
ATOM   3534 N N    . HIS A 1 229 ? 20.55876  -21.72590 6.45851   1.000 56.97881  ? 243 HIS A N    1 
ATOM   3535 C CA   . HIS A 1 229 ? 21.02099  -23.10301 6.28961   1.000 60.56777  ? 243 HIS A CA   1 
ATOM   3536 C C    . HIS A 1 229 ? 21.92451  -23.23073 5.06261   1.000 61.98683  ? 243 HIS A C    1 
ATOM   3537 O O    . HIS A 1 229 ? 22.58645  -24.25252 4.86558   1.000 62.71053  ? 243 HIS A O    1 
ATOM   3538 C CB   . HIS A 1 229 ? 19.82817  -24.05528 6.16225   1.000 61.99018  ? 243 HIS A CB   1 
ATOM   3539 C CG   . HIS A 1 229 ? 18.87790  -23.99172 7.31784   1.000 63.30253  ? 243 HIS A CG   1 
ATOM   3540 N ND1  . HIS A 1 229 ? 18.76938  -25.00287 8.24753   1.000 63.90686  ? 243 HIS A ND1  1 
ATOM   3541 C CD2  . HIS A 1 229 ? 17.99341  -23.03801 7.69537   1.000 63.88949  ? 243 HIS A CD2  1 
ATOM   3542 C CE1  . HIS A 1 229 ? 17.85852  -24.67639 9.14718   1.000 64.16251  ? 243 HIS A CE1  1 
ATOM   3543 N NE2  . HIS A 1 229 ? 17.37194  -23.48866 8.83516   1.000 63.99044  ? 243 HIS A NE2  1 
ATOM   3544 H H    . HIS A 1 229 ? 20.75585  -21.38098 7.22126   1.000 68.36946  ? 243 HIS A H    1 
ATOM   3545 H HA   . HIS A 1 229 ? 21.53401  -23.36257 7.07086   1.000 72.67621  ? 243 HIS A HA   1 
ATOM   3546 H HB2  . HIS A 1 229 ? 19.33311  -23.82909 5.35934   1.000 74.38310  ? 243 HIS A HB2  1 
ATOM   3547 H HB3  . HIS A 1 229 ? 20.16035  -24.96464 6.10205   1.000 74.38310  ? 243 HIS A HB3  1 
ATOM   3548 H HD1  . HIS A 1 229 ? 19.22386  -25.73295 8.24292   0.759 76.68313  ? 243 HIS A HD1  1 
ATOM   3549 H HD2  . HIS A 1 229 ? 17.83607  -22.22932 7.26390   1.000 76.66228  ? 243 HIS A HD2  1 
ATOM   3550 H HE1  . HIS A 1 229 ? 17.60338  -25.19461 9.87605   0.124 76.98990  ? 243 HIS A HE1  1 
HETATM 3551 C C1   . BEM B 2 .   ? 18.04664  2.42435   1.29415   1.000 53.30847  ? 1   BEM B C1   1 
HETATM 3552 C C2   . BEM B 2 .   ? 16.92149  1.72821   0.55630   1.000 52.46508  ? 1   BEM B C2   1 
HETATM 3553 O O2   . BEM B 2 .   ? 17.41117  0.50330   -0.03364  1.000 53.45187  ? 1   BEM B O2   1 
HETATM 3554 C C3   . BEM B 2 .   ? 15.82035  1.42901   1.50267   1.000 49.80761  ? 1   BEM B C3   1 
HETATM 3555 O O3   . BEM B 2 .   ? 16.13877  0.18333   2.17832   1.000 51.08813  ? 1   BEM B O3   1 
HETATM 3556 C C4   . BEM B 2 .   ? 15.60966  2.49346   2.54426   1.000 45.45283  ? 1   BEM B C4   1 
HETATM 3557 O O4   . BEM B 2 .   ? 14.19607  2.67175   2.67636   1.000 35.25611  ? 1   BEM B O4   1 
HETATM 3558 C C5   . BEM B 2 .   ? 16.23043  3.85635   2.18841   1.000 51.18082  ? 1   BEM B C5   1 
HETATM 3559 O O5   . BEM B 2 .   ? 17.61674  3.80756   1.68361   1.000 52.69780  ? 1   BEM B O5   1 
HETATM 3560 C C6   . BEM B 2 .   ? 16.25312  4.70459   3.42400   1.000 54.71909  ? 1   BEM B C6   1 
HETATM 3561 O O6B  . BEM B 2 .   ? 15.23307  5.37637   3.75209   1.000 55.96080  ? 1   BEM B O6B  1 
HETATM 3562 O O6A  . BEM B 2 .   ? 17.30025  4.74730   4.13086   1.000 55.89829  ? 1   BEM B O6A  1 
HETATM 3563 O O1   . BEM B 2 .   ? 18.35014  1.71355   2.41359   1.000 53.78676  ? 1   BEM B O1   1 
HETATM 3564 H H1   . BEM B 2 .   ? 18.84193  2.46505   0.74030   1.000 63.96505  ? 1   BEM B H1   1 
HETATM 3565 H H2   . BEM B 2 .   ? 16.59714  2.28378   -0.16967  1.000 62.95299  ? 1   BEM B H2   1 
HETATM 3566 H HO2  . BEM B 2 .   ? 17.59170  -0.05749  0.57900   1.000 64.13714  ? 1   BEM B HO2  1 
HETATM 3567 H H3   . BEM B 2 .   ? 14.99806  1.34619   0.99486   1.000 59.76402  ? 1   BEM B H3   1 
HETATM 3568 H HO3  . BEM B 2 .   ? 15.80956  0.19053   2.96193   1.000 61.30065  ? 1   BEM B HO3  1 
HETATM 3569 H H4   . BEM B 2 .   ? 16.01676  2.19720   3.37335   1.000 54.53829  ? 1   BEM B H4   1 
HETATM 3570 H H5   . BEM B 2 .   ? 15.67089  4.23474   1.49226   1.000 61.41187  ? 1   BEM B H5   1 
HETATM 3571 H HO1  . BEM B 2 .   ? 18.31523  2.22489   3.09215   1.000 64.53901  ? 1   BEM B HO1  1 
HETATM 3572 C C1   . LGU B 2 .   ? 13.68019  2.23043   3.94101   1.000 26.74372  ? 2   LGU B C1   1 
HETATM 3573 C C2   . LGU B 2 .   ? 12.20192  2.57021   4.01624   1.000 24.29945  ? 2   LGU B C2   1 
HETATM 3574 O O2   . LGU B 2 .   ? 12.04833  3.96845   3.70524   1.000 25.74506  ? 2   LGU B O2   1 
HETATM 3575 C C3   . LGU B 2 .   ? 11.39079  1.76120   3.06207   1.000 21.65291  ? 2   LGU B C3   1 
HETATM 3576 O O3   . LGU B 2 .   ? 11.74272  2.16399   1.70144   1.000 22.86741  ? 2   LGU B O3   1 
HETATM 3577 C C4   . LGU B 2 .   ? 11.63332  0.28186   3.21041   1.000 18.44018  ? 2   LGU B C4   1 
HETATM 3578 O O4   . LGU B 2 .   ? 11.13012  -0.21955  4.44802   1.000 17.42391  ? 2   LGU B O4   1 
HETATM 3579 C C5   . LGU B 2 .   ? 13.12854  -0.01678  3.16999   1.000 18.89890  ? 2   LGU B C5   1 
HETATM 3580 O O5   . LGU B 2 .   ? 13.86782  0.77241   4.15588   1.000 21.13397  ? 2   LGU B O5   1 
HETATM 3581 C C6   . LGU B 2 .   ? 13.37227  -1.46010  3.46841   1.000 17.51110  ? 2   LGU B C6   1 
HETATM 3582 O O6B  . LGU B 2 .   ? 12.90445  -2.32658  2.68596   1.000 17.89941  ? 2   LGU B O6B  1 
HETATM 3583 O O6A  . LGU B 2 .   ? 14.05451  -1.78410  4.47900   1.000 17.26742  ? 2   LGU B O6A  1 
HETATM 3584 H H1   . LGU B 2 .   ? 14.16116  2.71185   4.63224   1.000 32.08736  ? 2   LGU B H1   1 
HETATM 3585 H H2   . LGU B 2 .   ? 11.87557  2.40012   4.91372   1.000 29.15423  ? 2   LGU B H2   1 
HETATM 3586 H HO2  . LGU B 2 .   ? 12.76282  4.25865   3.34580   1.000 30.88897  ? 2   LGU B HO2  1 
HETATM 3587 H H3   . LGU B 2 .   ? 10.45005  1.93523   3.22213   1.000 25.97839  ? 2   LGU B H3   1 
HETATM 3588 H HO3  . LGU B 2 .   ? 12.23551  2.85659   1.72942   1.000 27.43579  ? 2   LGU B HO3  1 
HETATM 3589 H H4   . LGU B 2 .   ? 11.15309  -0.16645  2.49675   1.000 22.12310  ? 2   LGU B H4   1 
HETATM 3590 H H5   . LGU B 2 .   ? 13.44696  0.18095   2.27534   1.000 22.67358  ? 2   LGU B H5   1 
HETATM 3591 C C1   . BEM B 2 .   ? 9.80650   -0.70409  4.34707   1.000 17.50502  ? 3   BEM B C1   1 
HETATM 3592 C C2   . BEM B 2 .   ? 9.50637   -1.68228  5.46062   1.000 17.23916  ? 3   BEM B C2   1 
HETATM 3593 O O2   . BEM B 2 .   ? 9.71293   -1.05546  6.73830   1.000 17.55267  ? 3   BEM B O2   1 
HETATM 3594 C C3   . BEM B 2 .   ? 8.09745   -2.15018  5.36725   1.000 17.94944  ? 3   BEM B C3   1 
HETATM 3595 O O3   . BEM B 2 .   ? 7.80611   -2.98347  6.52207   1.000 17.86431  ? 3   BEM B O3   1 
HETATM 3596 C C4   . BEM B 2 .   ? 7.10346   -1.02202  5.29014   1.000 19.41204  ? 3   BEM B C4   1 
HETATM 3597 O O4   . BEM B 2 .   ? 5.84941   -1.53249  4.83181   1.000 20.66718  ? 3   BEM B O4   1 
HETATM 3598 C C5   . BEM B 2 .   ? 7.51492   0.04137   4.26642   1.000 20.17717  ? 3   BEM B C5   1 
HETATM 3599 O O5   . BEM B 2 .   ? 8.90746   0.45153   4.42639   1.000 18.56297  ? 3   BEM B O5   1 
HETATM 3600 C C6   . BEM B 2 .   ? 6.71735   1.29408   4.43907   1.000 23.42528  ? 3   BEM B C6   1 
HETATM 3601 O O6B  . BEM B 2 .   ? 5.98709   1.70020   3.49346   1.000 27.39557  ? 3   BEM B O6B  1 
HETATM 3602 O O6A  . BEM B 2 .   ? 6.79878   1.94558   5.51831   1.000 24.84975  ? 3   BEM B O6A  1 
HETATM 3603 H H1   . BEM B 2 .   ? 9.69822   -1.19678  3.51855   1.000 21.00092  ? 3   BEM B H1   1 
HETATM 3604 H H2   . BEM B 2 .   ? 10.11601  -2.43454  5.40281   1.000 20.68189  ? 3   BEM B H2   1 
HETATM 3605 H HO2  . BEM B 2 .   ? 10.08525  -0.30070  6.62573   1.000 21.05810  ? 3   BEM B HO2  1 
HETATM 3606 H H3   . BEM B 2 .   ? 8.00033   -2.67978  4.56042   1.000 21.53422  ? 3   BEM B H3   1 
HETATM 3607 H HO3  . BEM B 2 .   ? 8.37682   -3.61086  6.56718   1.000 21.43206  ? 3   BEM B HO3  1 
HETATM 3608 H H4   . BEM B 2 .   ? 7.02469   -0.63903  6.17784   1.000 23.28934  ? 3   BEM B H4   1 
HETATM 3609 H H5   . BEM B 2 .   ? 7.34792   -0.34709  3.39343   1.000 24.20749  ? 3   BEM B H5   1 
HETATM 3610 C C1   . BEM B 2 .   ? 4.75366   -0.98611  5.60049   1.000 21.12104  ? 4   BEM B C1   1 
HETATM 3611 C C2   . BEM B 2 .   ? 3.39813   -0.97033  4.90310   1.000 22.88048  ? 4   BEM B C2   1 
HETATM 3612 O O2   . BEM B 2 .   ? 3.53964   -0.22793  3.67941   1.000 24.99493  ? 4   BEM B O2   1 
HETATM 3613 C C3   . BEM B 2 .   ? 2.82112   -2.31823  4.64490   1.000 24.16236  ? 4   BEM B C3   1 
HETATM 3614 O O3   . BEM B 2 .   ? 3.61060   -3.02160  3.63917   1.000 27.07085  ? 4   BEM B O3   1 
HETATM 3615 C C4   . BEM B 2 .   ? 2.68174   -3.10760  5.92853   0.558 22.84514  ? 4   BEM B C4   1 
HETATM 3616 O O4   . BEM B 2 .   ? 1.55220   -2.59976  6.66017   0.215 23.82293  ? 4   BEM B O4   1 
HETATM 3617 C C5   . BEM B 2 .   ? 3.71587   -2.88684  7.01827   0.584 21.13053  ? 4   BEM B C5   1 
HETATM 3618 O O5   . BEM B 2 .   ? 4.67655   -1.80667  6.82392   1.000 20.11060  ? 4   BEM B O5   1 
HETATM 3619 C C6   . BEM B 2 .   ? 4.47020   -4.09327  7.48062   1.000 20.36939  ? 4   BEM B C6   1 
HETATM 3620 O O6B  . BEM B 2 .   ? 3.97993   -5.24504  7.33958   1.000 20.44025  ? 4   BEM B O6B  1 
HETATM 3621 O O6A  . BEM B 2 .   ? 5.56040   -3.89038  8.07716   1.000 20.66123  ? 4   BEM B O6A  1 
HETATM 3622 H H1   . BEM B 2 .   ? 4.93149   -0.04234  5.73679   1.000 25.34013  ? 4   BEM B H1   1 
HETATM 3623 H H2   . BEM B 2 .   ? 2.75847   -0.52238  5.47849   1.000 27.45147  ? 4   BEM B H2   1 
HETATM 3624 H HO2  . BEM B 2 .   ? 4.32931   -0.32552  3.37853   1.000 29.98880  ? 4   BEM B HO2  1 
HETATM 3625 H H3   . BEM B 2 .   ? 1.93571   -2.23029  4.25862   1.000 28.98973  ? 4   BEM B H3   1 
HETATM 3626 H HO3  . BEM B 2 .   ? 4.17559   -2.48715  3.29474   1.000 32.47991  ? 4   BEM B HO3  1 
HETATM 3627 H H4   . BEM B 2 .   ? 2.66760   -4.02081  5.60181   1.000 27.40906  ? 4   BEM B H4   1 
HETATM 3628 H H5   . BEM B 2 .   ? 3.11111   -2.64827  7.73816   1.000 25.35153  ? 4   BEM B H5   1 
HETATM 3629 C C1   . BEM B 2 .   ? 0.69798   -3.65843  7.10704   1.000 24.12544  ? 5   BEM B C1   1 
HETATM 3630 C C2   . BEM B 2 .   ? -0.30654  -3.26286  8.17973   1.000 25.66778  ? 5   BEM B C2   1 
HETATM 3631 O O2   . BEM B 2 .   ? -0.94051  -2.04017  7.76675   1.000 27.92277  ? 5   BEM B O2   1 
HETATM 3632 C C3   . BEM B 2 .   ? -1.36122  -4.30200  8.41812   1.000 25.39713  ? 5   BEM B C3   1 
HETATM 3633 O O3   . BEM B 2 .   ? -2.35921  -3.76096  9.32340   1.000 26.56040  ? 5   BEM B O3   1 
HETATM 3634 C C4   . BEM B 2 .   ? -2.01971  -4.80685  7.16231   1.000 24.85012  ? 5   BEM B C4   1 
HETATM 3635 O O4   . BEM B 2 .   ? -2.75672  -5.99923  7.44794   1.000 27.07722  ? 5   BEM B O4   1 
HETATM 3636 C C5   . BEM B 2 .   ? -0.92944  -5.22502  6.18265   1.000 23.07811  ? 5   BEM B C5   1 
HETATM 3637 O O5   . BEM B 2 .   ? -0.01174  -4.13071  5.89904   1.000 23.31801  ? 5   BEM B O5   1 
HETATM 3638 C C6   . BEM B 2 .   ? -1.45615  -5.69292  4.86955   1.000 22.21473  ? 5   BEM B C6   1 
HETATM 3639 O O6B  . BEM B 2 .   ? -1.51439  -6.92961  4.69733   1.000 21.48583  ? 5   BEM B O6B  1 
HETATM 3640 O O6A  . BEM B 2 .   ? -1.78558  -4.88644  3.95777   1.000 23.25853  ? 5   BEM B O6A  1 
HETATM 3641 H H1   . BEM B 2 .   ? 1.24356   -4.32383  7.55480   1.000 28.94542  ? 5   BEM B H1   1 
HETATM 3642 H H2   . BEM B 2 .   ? 0.16869   -3.12839  9.01458   1.000 30.79623  ? 5   BEM B H2   1 
HETATM 3643 H HO2  . BEM B 2 .   ? -0.54527  -1.73442  7.07833   1.000 33.50222  ? 5   BEM B HO2  1 
HETATM 3644 H H3   . BEM B 2 .   ? -0.93705  -5.06757  8.83631   1.000 30.47145  ? 5   BEM B H3   1 
HETATM 3645 H HO3  . BEM B 2 .   ? -2.07409  -3.80935  10.12236  1.000 31.86738  ? 5   BEM B HO3  1 
HETATM 3646 H H4   . BEM B 2 .   ? -2.61812  -4.12860  6.81190   1.000 29.81503  ? 5   BEM B H4   1 
HETATM 3647 H H5   . BEM B 2 .   ? -0.48527  -5.97839  6.60221   1.000 27.68863  ? 5   BEM B H5   1 
HETATM 3648 C C1   . BEM B 2 .   ? -4.11136  -5.91571  7.02963   1.000 30.51752  ? 6   BEM B C1   1 
HETATM 3649 C C2   . BEM B 2 .   ? -4.74962  -7.29041  7.14714   1.000 31.15568  ? 6   BEM B C2   1 
HETATM 3650 O O2   . BEM B 2 .   ? -4.54803  -7.80152  8.48067   1.000 31.58536  ? 6   BEM B O2   1 
HETATM 3651 C C3   . BEM B 2 .   ? -6.20729  -7.24082  6.87121   1.000 33.46558  ? 6   BEM B C3   1 
HETATM 3652 O O3   . BEM B 2 .   ? -6.78081  -8.55607  7.10923   1.000 34.08802  ? 6   BEM B O3   1 
HETATM 3653 C C4   . BEM B 2 .   ? -6.89176  -6.23969  7.75107   1.000 35.49939  ? 6   BEM B C4   1 
HETATM 3654 O O4   . BEM B 2 .   ? -8.24876  -6.11638  7.32306   1.000 35.75836  ? 6   BEM B O4   1 
HETATM 3655 C C5   . BEM B 2 .   ? -6.24482  -4.85241  7.68575   1.000 36.92008  ? 6   BEM B C5   1 
HETATM 3656 O O5   . BEM B 2 .   ? -4.78783  -4.87809  7.85366   1.000 33.35130  ? 6   BEM B O5   1 
HETATM 3657 C C6   . BEM B 2 .   ? -6.76126  -4.00184  8.80247   1.000 41.71101  ? 6   BEM B C6   1 
HETATM 3658 O O6B  . BEM B 2 .   ? -7.40468  -2.94727  8.54314   1.000 43.24996  ? 6   BEM B O6B  1 
HETATM 3659 O O6A  . BEM B 2 .   ? -6.53477  -4.33757  10.00008  1.000 43.21415  ? 6   BEM B O6A  1 
HETATM 3660 H H1   . BEM B 2 .   ? -4.18329  -5.67571  6.09254   1.000 36.61592  ? 6   BEM B H1   1 
HETATM 3661 H H2   . BEM B 2 .   ? -4.32054  -7.88889  6.51577   1.000 37.38171  ? 6   BEM B H2   1 
HETATM 3662 H HO2  . BEM B 2 .   ? -4.85925  -7.25079  9.04809   1.000 37.89732  ? 6   BEM B HO2  1 
HETATM 3663 H H3   . BEM B 2 .   ? -6.35183  -7.00349  5.94186   1.000 40.15359  ? 6   BEM B H3   1 
HETATM 3664 H HO3  . BEM B 2 .   ? -6.31388  -9.14784  6.71627   1.000 40.90051  ? 6   BEM B HO3  1 
HETATM 3665 H H4   . BEM B 2 .   ? -6.85428  -6.55923  8.66615   1.000 42.59416  ? 6   BEM B H4   1 
HETATM 3666 H HO4  . BEM B 2 .   ? -8.71122  -5.76007  7.94125   1.000 42.90492  ? 6   BEM B HO4  1 
HETATM 3667 H H5   . BEM B 2 .   ? -6.47936  -4.48335  6.81991   1.000 44.29899  ? 6   BEM B H5   1 
HETATM 3668 C C1   . BEM C 3 .   ? 8.50565   -14.33830 33.20833  1.000 27.61476  ? 1   BEM C C1   1 
HETATM 3669 C C2   . BEM C 3 .   ? 8.31149   -13.27558 32.14065  1.000 24.76031  ? 1   BEM C C2   1 
HETATM 3670 O O2   . BEM C 3 .   ? 6.91697   -12.91450 32.10171  1.000 24.92322  ? 1   BEM C O2   1 
HETATM 3671 C C3   . BEM C 3 .   ? 9.12398   -12.06388 32.43125  1.000 22.33408  ? 1   BEM C C3   1 
HETATM 3672 O O3   . BEM C 3 .   ? 8.79400   -11.01938 31.48650  1.000 20.98011  ? 1   BEM C O3   1 
HETATM 3673 C C4   . BEM C 3 .   ? 8.88942   -11.53142 33.81089  1.000 23.49541  ? 1   BEM C C4   1 
HETATM 3674 O O4   . BEM C 3 .   ? 9.84838   -10.50856 34.07643  1.000 21.97832  ? 1   BEM C O4   1 
HETATM 3675 C C5   . BEM C 3 .   ? 9.05755   -12.64062 34.84659  1.000 27.85613  ? 1   BEM C C5   1 
HETATM 3676 O O5   . BEM C 3 .   ? 8.15294   -13.75914 34.54264  1.000 28.37037  ? 1   BEM C O5   1 
HETATM 3677 C C6   . BEM C 3 .   ? 8.76110   -12.11266 36.21191  1.000 32.12026  ? 1   BEM C C6   1 
HETATM 3678 O O6B  . BEM C 3 .   ? 9.64048   -11.44775 36.83370  1.000 33.18715  ? 1   BEM C O6B  1 
HETATM 3679 O O6A  . BEM C 3 .   ? 7.63026   -12.33947 36.72176  1.000 33.72755  ? 1   BEM C O6A  1 
HETATM 3680 O O1   . BEM C 3 .   ? 7.72005   -15.42099 32.96413  1.000 28.56021  ? 1   BEM C O1   1 
HETATM 3681 H H1   . BEM C 3 .   ? 9.42240   -14.65492 33.19319  1.000 33.13260  ? 1   BEM C H1   1 
HETATM 3682 H H2   . BEM C 3 .   ? 8.56899   -13.62939 31.27496  1.000 29.70727  ? 1   BEM C H2   1 
HETATM 3683 H HO2  . BEM C 3 .   ? 6.49853   -13.45766 31.60001  1.000 29.90275  ? 1   BEM C HO2  1 
HETATM 3684 H H3   . BEM C 3 .   ? 10.05862  -12.30456 32.33420  1.000 26.79579  ? 1   BEM C H3   1 
HETATM 3685 H HO3  . BEM C 3 .   ? 8.34915   -10.41302 31.88220  1.000 25.17103  ? 1   BEM C HO3  1 
HETATM 3686 H H4   . BEM C 3 .   ? 7.99907   -11.15144 33.87244  1.000 28.18939  ? 1   BEM C H4   1 
HETATM 3687 H H5   . BEM C 3 .   ? 9.97739   -12.94850 34.84934  1.000 33.42225  ? 1   BEM C H5   1 
HETATM 3688 H HO1  . BEM C 3 .   ? 8.17656   -16.01405 32.56203  1.000 34.26714  ? 1   BEM C HO1  1 
HETATM 3689 C C1   . BEM C 3 .   ? 9.22041   -9.29992  34.49433  1.000 20.77306  ? 2   BEM C C1   1 
HETATM 3690 C C2   . BEM C 3 .   ? 10.24474  -8.33545  35.06004  1.000 20.58056  ? 2   BEM C C2   1 
HETATM 3691 O O2   . BEM C 3 .   ? 11.31080  -8.20682  34.10046  1.000 21.27185  ? 2   BEM C O2   1 
HETATM 3692 C C3   . BEM C 3 .   ? 9.68034   -6.98735  35.32903  1.000 20.65997  ? 2   BEM C C3   1 
HETATM 3693 O O3   . BEM C 3 .   ? 10.75146  -6.08402  35.73746  1.000 22.54726  ? 2   BEM C O3   1 
HETATM 3694 C C4   . BEM C 3 .   ? 8.96102   -6.42033  34.14563  1.000 20.24495  ? 2   BEM C C4   1 
HETATM 3695 O O4   . BEM C 3 .   ? 8.29721   -5.24245  34.58417  1.000 20.91184  ? 2   BEM C O4   1 
HETATM 3696 C C5   . BEM C 3 .   ? 7.91746   -7.40439  33.63684  1.000 19.76008  ? 2   BEM C C5   1 
HETATM 3697 O O5   . BEM C 3 .   ? 8.52244   -8.69666  33.33982  1.000 20.30472  ? 2   BEM C O5   1 
HETATM 3698 C C6   . BEM C 3 .   ? 7.33123   -6.91296  32.35767  1.000 20.67820  ? 2   BEM C C6   1 
HETATM 3699 O O6B  . BEM C 3 .   ? 6.16209   -6.44871  32.34715  1.000 22.67709  ? 2   BEM C O6B  1 
HETATM 3700 O O6A  . BEM C 3 .   ? 8.02839   -6.94260  31.30232  1.000 20.31652  ? 2   BEM C O6A  1 
HETATM 3701 H H1   . BEM C 3 .   ? 8.59920   -9.49831  35.21241  1.000 24.92256  ? 2   BEM C H1   1 
HETATM 3702 H H2   . BEM C 3 .   ? 10.58597  -8.69267  35.89482  1.000 24.69156  ? 2   BEM C H2   1 
HETATM 3703 H HO2  . BEM C 3 .   ? 10.98917  -8.23999  33.31480  1.000 25.52111  ? 2   BEM C HO2  1 
HETATM 3704 H H3   . BEM C 3 .   ? 9.04737   -7.05908  36.06054  1.000 24.78686  ? 2   BEM C H3   1 
HETATM 3705 H HO3  . BEM C 3 .   ? 10.68919  -5.35451  35.30488  1.000 27.05161  ? 2   BEM C HO3  1 
HETATM 3706 H H4   . BEM C 3 .   ? 9.58192   -6.20637  33.43177  1.000 24.28884  ? 2   BEM C H4   1 
HETATM 3707 H H5   . BEM C 3 .   ? 7.22251   -7.47971  34.30935  1.000 23.70698  ? 2   BEM C H5   1 
HETATM 3708 C C1   . BEM C 3 .   ? 8.29439   -4.22230  33.58639  1.000 22.25719  ? 3   BEM C C1   1 
HETATM 3709 C C2   . BEM C 3 .   ? 7.31290   -3.13196  33.96511  1.000 23.82468  ? 3   BEM C C2   1 
HETATM 3710 O O2   . BEM C 3 .   ? 7.67554   -2.58949  35.24901  1.000 25.14309  ? 3   BEM C O2   1 
HETATM 3711 C C3   . BEM C 3 .   ? 7.31545   -2.05501  32.94938  1.000 23.98180  ? 3   BEM C C3   1 
HETATM 3712 O O3   . BEM C 3 .   ? 6.48836   -0.96295  33.41951  1.000 25.19320  ? 3   BEM C O3   1 
HETATM 3713 C C4   . BEM C 3 .   ? 8.68881   -1.53920  32.63643  1.000 22.89805  ? 3   BEM C C4   1 
HETATM 3714 O O4   . BEM C 3 .   ? 8.56618   -0.67862  31.50444  1.000 23.68097  ? 3   BEM C O4   1 
HETATM 3715 C C5   . BEM C 3 .   ? 9.61809   -2.70688  32.30661  1.000 22.64541  ? 3   BEM C C5   1 
HETATM 3716 O O5   . BEM C 3 .   ? 9.64988   -3.64782  33.42469  1.000 21.74000  ? 3   BEM C O5   1 
HETATM 3717 C C6   . BEM C 3 .   ? 11.02166  -2.27039  32.05321  1.000 23.21867  ? 3   BEM C C6   1 
HETATM 3718 O O6B  . BEM C 3 .   ? 11.34594  -1.84043  30.91097  1.000 22.47500  ? 3   BEM C O6B  1 
HETATM 3719 O O6A  . BEM C 3 .   ? 11.87796  -2.36504  32.97422  1.000 24.07502  ? 3   BEM C O6A  1 
HETATM 3720 H H1   . BEM C 3 .   ? 7.99698   -4.61750  32.75197  1.000 26.70352  ? 3   BEM C H1   1 
HETATM 3721 H H2   . BEM C 3 .   ? 6.42002   -3.50324  34.04131  1.000 28.58450  ? 3   BEM C H2   1 
HETATM 3722 H HO2  . BEM C 3 .   ? 8.52234   -2.57499  35.32141  1.000 30.16661  ? 3   BEM C HO2  1 
HETATM 3723 H H3   . BEM C 3 .   ? 6.93925   -2.41152  32.12946  1.000 28.77305  ? 3   BEM C H3   1 
HETATM 3724 H HO3  . BEM C 3 .   ? 6.90491   -0.22844  33.31571  1.000 30.22673  ? 3   BEM C HO3  1 
HETATM 3725 H H4   . BEM C 3 .   ? 9.06246   -1.03527  33.37625  1.000 27.47255  ? 3   BEM C H4   1 
HETATM 3726 H H5   . BEM C 3 .   ? 9.29475   -3.11133  31.48638  1.000 27.16939  ? 3   BEM C H5   1 
HETATM 3727 C C1   . BEM C 3 .   ? 9.38077   0.48775   31.63472  1.000 26.45869  ? 4   BEM C C1   1 
HETATM 3728 C C2   . BEM C 3 .   ? 9.49065   1.18327   30.29218  1.000 27.06718  ? 4   BEM C C2   1 
HETATM 3729 O O2   . BEM C 3 .   ? 8.14847   1.46245   29.84159  1.000 25.95856  ? 4   BEM C O2   1 
HETATM 3730 C C3   . BEM C 3 .   ? 10.29544  2.43516   30.40255  1.000 28.71249  ? 4   BEM C C3   1 
HETATM 3731 O O3   . BEM C 3 .   ? 10.28819  3.13303   29.12770  1.000 28.70443  ? 4   BEM C O3   1 
HETATM 3732 C C4   . BEM C 3 .   ? 9.78304   3.35193   31.47330  1.000 31.27801  ? 4   BEM C C4   1 
HETATM 3733 O O4   . BEM C 3 .   ? 10.69026  4.44131   31.65515  1.000 32.74435  ? 4   BEM C O4   1 
HETATM 3734 C C5   . BEM C 3 .   ? 9.63428   2.62140   32.80692  1.000 32.48125  ? 4   BEM C C5   1 
HETATM 3735 O O5   . BEM C 3 .   ? 8.81698   1.40736   32.66266  1.000 29.21160  ? 4   BEM C O5   1 
HETATM 3736 C C6   . BEM C 3 .   ? 8.96712   3.53633   33.78677  1.000 36.96414  ? 4   BEM C C6   1 
HETATM 3737 O O6B  . BEM C 3 .   ? 9.61868   4.46008   34.35871  1.000 39.21001  ? 4   BEM C O6B  1 
HETATM 3738 O O6A  . BEM C 3 .   ? 7.74034   3.37755   34.02929  1.000 38.49690  ? 4   BEM C O6A  1 
HETATM 3739 H H1   . BEM C 3 .   ? 10.27351  0.21530   31.89870  1.000 31.74532  ? 4   BEM C H1   1 
HETATM 3740 H H2   . BEM C 3 .   ? 9.92130   0.61632   29.63340  1.000 32.47551  ? 4   BEM C H2   1 
HETATM 3741 H HO2  . BEM C 3 .   ? 7.60144   1.33094   30.47898  1.000 31.14517  ? 4   BEM C HO2  1 
HETATM 3742 H H3   . BEM C 3 .   ? 11.20994  2.19192   30.61567  1.000 34.44988  ? 4   BEM C H3   1 
HETATM 3743 H HO3  . BEM C 3 .   ? 9.60552   3.63736   29.08344  1.000 34.44020  ? 4   BEM C HO3  1 
HETATM 3744 H H4   . BEM C 3 .   ? 8.92539   3.70635   31.19095  1.000 37.52850  ? 4   BEM C H4   1 
HETATM 3745 H HO4  . BEM C 3 .   ? 10.25764  5.13893   31.87695  1.000 39.28812  ? 4   BEM C HO4  1 
HETATM 3746 H H5   . BEM C 3 .   ? 10.51235  2.38189   33.14236  1.000 38.97240  ? 4   BEM C H5   1 
HETATM 3747 O O    . HOH D 4 .   ? -5.69983  -3.14190  28.75019  1.000 50.67891  ? 301 HOH A O    1 
HETATM 3748 O O    . HOH D 4 .   ? 24.67154  -14.03647 27.34506  1.000 65.45111  ? 302 HOH A O    1 
HETATM 3749 O O    . HOH D 4 .   ? 12.37453  -10.77695 34.58851  1.000 51.85362  ? 303 HOH A O    1 
HETATM 3750 O O    . HOH D 4 .   ? -4.94343  -13.67045 28.76475  1.000 108.37110 ? 304 HOH A O    1 
HETATM 3751 O O    . HOH D 4 .   ? 22.32013  -11.22567 30.76712  1.000 50.36055  ? 305 HOH A O    1 
HETATM 3752 O O    . HOH D 4 .   ? 3.32734   -24.57329 -2.48797  1.000 54.55377  ? 306 HOH A O    1 
HETATM 3753 O O    . HOH D 4 .   ? 18.96905  -23.51975 3.02482   1.000 37.38882  ? 307 HOH A O    1 
HETATM 3754 O O    . HOH D 4 .   ? 9.28739   -3.52560  2.14253   1.000 48.55987  ? 308 HOH A O    1 
HETATM 3755 O O    . HOH D 4 .   ? 20.64353  -4.74692  -0.97940  1.000 47.35555  ? 309 HOH A O    1 
HETATM 3756 O O    . HOH D 4 .   ? -15.16081 -9.79258  15.88155  1.000 90.84065  ? 310 HOH A O    1 
HETATM 3757 O O    . HOH D 4 .   ? 5.74382   -23.21350 -6.55095  1.000 41.57745  ? 311 HOH A O    1 
HETATM 3758 O O    . HOH D 4 .   ? 11.23021  -12.68258 -10.39731 1.000 40.12658  ? 312 HOH A O    1 
HETATM 3759 O O    . HOH D 4 .   ? 20.74555  -13.52137 11.66114  1.000 42.39820  ? 313 HOH A O    1 
HETATM 3760 O O    . HOH D 4 .   ? 30.30097  1.95573   19.81179  1.000 44.39867  ? 314 HOH A O    1 
HETATM 3761 O O    . HOH D 4 .   ? -4.58592  -8.61744  11.67376  1.000 46.79608  ? 315 HOH A O    1 
HETATM 3762 O O    . HOH D 4 .   ? 0.46378   -4.91147  -2.86686  1.000 46.62581  ? 316 HOH A O    1 
HETATM 3763 O O    . HOH D 4 .   ? 5.70044   -28.33124 7.96647   1.000 29.95686  ? 317 HOH A O    1 
HETATM 3764 O O    . HOH D 4 .   ? 6.78243   -25.92182 5.12229   1.000 35.01658  ? 318 HOH A O    1 
HETATM 3765 O O    . HOH D 4 .   ? 13.24973  -15.53787 -8.58265  1.000 52.69533  ? 319 HOH A O    1 
HETATM 3766 O O    . HOH D 4 .   ? -0.42252  3.81595   20.23992  1.000 16.84708  ? 320 HOH A O    1 
HETATM 3767 O O    . HOH D 4 .   ? -9.72053  -4.45224  20.01413  1.000 51.49193  ? 321 HOH A O    1 
HETATM 3768 O O    . HOH D 4 .   ? -6.81017  -11.41621 -4.82802  1.000 53.31124  ? 322 HOH A O    1 
HETATM 3769 O O    . HOH D 4 .   ? 2.28824   8.80047   19.38271  1.000 40.57009  ? 323 HOH A O    1 
HETATM 3770 O O    . HOH D 4 .   ? 20.09740  -0.84049  33.05537  1.000 28.02948  ? 324 HOH A O    1 
HETATM 3771 O O    . HOH D 4 .   ? 7.42652   -7.30447  13.92336  1.000 15.07424  ? 325 HOH A O    1 
HETATM 3772 O O    . HOH D 4 .   ? -5.52544  5.99079   17.87272  1.000 32.17213  ? 326 HOH A O    1 
HETATM 3773 O O    . HOH D 4 .   ? 2.81324   5.79969   26.71044  1.000 52.26218  ? 327 HOH A O    1 
HETATM 3774 O O    . HOH D 4 .   ? -15.39944 -14.51869 12.31756  1.000 25.46592  ? 328 HOH A O    1 
HETATM 3775 O O    . HOH D 4 .   ? 27.04254  -6.02582  10.72522  1.000 18.37087  ? 329 HOH A O    1 
HETATM 3776 O O    . HOH D 4 .   ? -1.10093  -8.96034  -7.44096  1.000 46.29142  ? 330 HOH A O    1 
HETATM 3777 O O    . HOH D 4 .   ? -1.34812  -27.53578 5.14272   1.000 52.56213  ? 331 HOH A O    1 
HETATM 3778 O O    . HOH D 4 .   ? -3.04905  -23.53987 -2.20925  1.000 36.79492  ? 332 HOH A O    1 
HETATM 3779 O O    . HOH D 4 .   ? -7.51748  -15.46855 -2.72969  1.000 46.91171  ? 333 HOH A O    1 
HETATM 3780 O O    . HOH D 4 .   ? -5.95029  -4.52786  14.20960  1.000 29.70270  ? 334 HOH A O    1 
HETATM 3781 O O    . HOH D 4 .   ? 10.89658  -19.83832 24.37041  1.000 25.25132  ? 335 HOH A O    1 
HETATM 3782 O O    . HOH D 4 .   ? 0.61571   -26.18417 0.78196   1.000 53.33144  ? 336 HOH A O    1 
HETATM 3783 O O    . HOH D 4 .   ? 8.95909   -14.97835 -3.08191  1.000 22.33432  ? 337 HOH A O    1 
HETATM 3784 O O    . HOH D 4 .   ? 8.43766   -23.83926 11.84981  1.000 14.95127  ? 338 HOH A O    1 
HETATM 3785 O O    . HOH D 4 .   ? 17.75467  -13.66016 26.82492  1.000 15.86514  ? 339 HOH A O    1 
HETATM 3786 O O    . HOH D 4 .   ? 7.03167   -28.28320 22.99256  1.000 15.06662  ? 340 HOH A O    1 
HETATM 3787 O O    . HOH D 4 .   ? -3.24380  3.75965   27.91259  1.000 44.13154  ? 341 HOH A O    1 
HETATM 3788 O O    . HOH D 4 .   ? 5.33334   0.68398   27.13449  1.000 59.26019  ? 342 HOH A O    1 
HETATM 3789 O O    . HOH D 4 .   ? 10.23530  -26.81518 11.15877  1.000 37.60768  ? 343 HOH A O    1 
HETATM 3790 O O    . HOH D 4 .   ? 20.43274  -14.00099 27.35540  1.000 16.48358  ? 344 HOH A O    1 
HETATM 3791 O O    . HOH D 4 .   ? 14.65425  7.45883   12.65392  1.000 22.81149  ? 345 HOH A O    1 
HETATM 3792 O O    . HOH D 4 .   ? 26.51795  2.89727   10.29559  1.000 34.79182  ? 346 HOH A O    1 
HETATM 3793 O O    . HOH D 4 .   ? 2.49204   1.17511   7.99333   1.000 38.94671  ? 347 HOH A O    1 
HETATM 3794 O O    . HOH D 4 .   ? 9.69694   -7.50022  -5.30630  1.000 37.28955  ? 348 HOH A O    1 
HETATM 3795 O O    . HOH D 4 .   ? 11.67562  -15.47300 29.61507  1.000 25.15533  ? 349 HOH A O    1 
HETATM 3796 O O    . HOH D 4 .   ? 2.60087   -4.60692  30.91066  1.000 42.74714  ? 350 HOH A O    1 
HETATM 3797 O O    . HOH D 4 .   ? -9.52629  -17.96242 10.38455  1.000 37.81252  ? 351 HOH A O    1 
HETATM 3798 O O    . HOH D 4 .   ? 29.28923  -2.46728  21.48295  1.000 34.73961  ? 352 HOH A O    1 
HETATM 3799 O O    . HOH D 4 .   ? 16.05359  -27.41678 4.58109   1.000 52.81471  ? 353 HOH A O    1 
HETATM 3800 O O    . HOH D 4 .   ? -0.78276  -23.35531 20.36143  1.000 34.57195  ? 354 HOH A O    1 
HETATM 3801 O O    . HOH D 4 .   ? -4.12772  -22.61070 4.74340   1.000 44.89349  ? 355 HOH A O    1 
HETATM 3802 O O    . HOH D 4 .   ? -3.56924  -17.33541 -4.07675  1.000 23.00536  ? 356 HOH A O    1 
HETATM 3803 O O    . HOH D 4 .   ? -5.85249  -22.73813 17.95687  1.000 48.56428  ? 357 HOH A O    1 
HETATM 3804 O O    . HOH D 4 .   ? -5.43911  -22.78632 15.20536  1.000 53.55935  ? 358 HOH A O    1 
HETATM 3805 O O    . HOH D 4 .   ? -8.62533  -17.20534 2.71701   1.000 47.29022  ? 359 HOH A O    1 
HETATM 3806 O O    . HOH D 4 .   ? 24.33389  -2.16702  32.46065  1.000 44.57010  ? 360 HOH A O    1 
HETATM 3807 O O    . HOH D 4 .   ? 10.74285  -17.65157 -9.60346  1.000 51.54947  ? 361 HOH A O    1 
HETATM 3808 O O    . HOH D 4 .   ? -7.89515  -5.87288  4.11380   1.000 52.22775  ? 362 HOH A O    1 
HETATM 3809 O O    . HOH D 4 .   ? 1.74476   -2.15984  26.11683  1.000 18.12331  ? 363 HOH A O    1 
HETATM 3810 O O    . HOH D 4 .   ? 17.22330  -16.20328 6.71916   1.000 42.74271  ? 364 HOH A O    1 
HETATM 3811 O O    . HOH D 4 .   ? 24.21334  -3.73065  7.64195   1.000 18.72015  ? 365 HOH A O    1 
HETATM 3812 O O    . HOH D 4 .   ? 29.07690  -5.88978  19.37418  1.000 27.16292  ? 366 HOH A O    1 
HETATM 3813 O O    . HOH D 4 .   ? 12.97584  -23.28702 17.34715  1.000 21.54100  ? 367 HOH A O    1 
HETATM 3814 O O    . HOH D 4 .   ? 19.95698  -1.22328  23.05452  1.000 12.05809  ? 368 HOH A O    1 
HETATM 3815 O O    . HOH D 4 .   ? 29.91101  -1.92599  15.47219  1.000 28.15747  ? 369 HOH A O    1 
HETATM 3816 O O    . HOH D 4 .   ? 23.19938  -9.05692  22.37003  1.000 14.39951  ? 370 HOH A O    1 
HETATM 3817 O O    . HOH D 4 .   ? 10.29656  8.68222   11.28468  1.000 38.29572  ? 371 HOH A O    1 
HETATM 3818 O O    . HOH D 4 .   ? -1.32995  -11.52902 12.35433  1.000 13.34204  ? 372 HOH A O    1 
HETATM 3819 O O    . HOH D 4 .   ? 14.29696  -25.34038 9.84536   1.000 41.16117  ? 373 HOH A O    1 
HETATM 3820 O O    . HOH D 4 .   ? 20.86508  -13.41513 17.79271  1.000 15.19210  ? 374 HOH A O    1 
HETATM 3821 O O    . HOH D 4 .   ? 6.53653   -27.26331 -2.37723  1.000 47.43046  ? 375 HOH A O    1 
HETATM 3822 O O    . HOH D 4 .   ? -5.41165  3.61798   14.76442  1.000 27.38383  ? 376 HOH A O    1 
HETATM 3823 O O    . HOH D 4 .   ? 12.94213  -21.91562 -0.98635  1.000 30.63463  ? 377 HOH A O    1 
HETATM 3824 O O    . HOH D 4 .   ? 0.27893   -29.80966 15.60654  1.000 27.46715  ? 378 HOH A O    1 
HETATM 3825 O O    . HOH D 4 .   ? -11.94216 -20.26386 14.46217  1.000 27.75096  ? 379 HOH A O    1 
HETATM 3826 O O    . HOH D 4 .   ? 30.11934  -8.31736  12.85270  1.000 27.51407  ? 380 HOH A O    1 
HETATM 3827 O O    . HOH D 4 .   ? -2.97592  -23.97540 10.51891  1.000 22.53823  ? 381 HOH A O    1 
HETATM 3828 O O    . HOH D 4 .   ? -2.84234  -5.54806  -6.44385  1.000 34.69401  ? 382 HOH A O    1 
HETATM 3829 O O    . HOH D 4 .   ? 4.11612   -11.66293 29.85900  1.000 18.92719  ? 383 HOH A O    1 
HETATM 3830 O O    . HOH D 4 .   ? 22.08940  5.63436   11.14564  1.000 41.76492  ? 384 HOH A O    1 
HETATM 3831 O O    . HOH D 4 .   ? 19.04599  -4.73514  31.85702  1.000 21.40979  ? 385 HOH A O    1 
HETATM 3832 O O    . HOH D 4 .   ? 14.09820  7.56308   22.66832  1.000 16.56117  ? 386 HOH A O    1 
HETATM 3833 O O    . HOH D 4 .   ? 22.48971  -16.24164 10.80775  1.000 51.45727  ? 387 HOH A O    1 
HETATM 3834 O O    . HOH D 4 .   ? -3.51903  -24.12453 13.93903  1.000 43.85860  ? 388 HOH A O    1 
HETATM 3835 O O    . HOH D 4 .   ? 7.68968   -20.04604 29.11305  1.000 40.35773  ? 389 HOH A O    1 
HETATM 3836 O O    . HOH D 4 .   ? -2.33648  -18.00858 8.92007   1.000 13.10597  ? 390 HOH A O    1 
HETATM 3837 O O    . HOH D 4 .   ? 10.31834  4.86626   23.56498  1.000 23.53787  ? 391 HOH A O    1 
HETATM 3838 O O    . HOH D 4 .   ? 24.41103  -6.33607  8.49530   1.000 17.63666  ? 392 HOH A O    1 
HETATM 3839 O O    . HOH D 4 .   ? 25.66251  1.97429   24.96064  1.000 33.26177  ? 393 HOH A O    1 
HETATM 3840 O O    . HOH D 4 .   ? -2.47616  -1.26679  18.44386  1.000 15.33016  ? 394 HOH A O    1 
HETATM 3841 O O    . HOH D 4 .   ? -1.62753  -21.10241 -4.85801  1.000 47.60832  ? 395 HOH A O    1 
HETATM 3842 O O    . HOH D 4 .   ? -20.51123 -17.21136 15.44877  1.000 24.15112  ? 396 HOH A O    1 
HETATM 3843 O O    . HOH D 4 .   ? -3.94167  -15.00423 27.58540  1.000 25.84096  ? 397 HOH A O    1 
HETATM 3844 O O    . HOH D 4 .   ? 13.55662  -17.99967 26.49222  1.000 25.05229  ? 398 HOH A O    1 
HETATM 3845 O O    . HOH D 4 .   ? 6.13903   5.70129   23.74414  1.000 25.46580  ? 399 HOH A O    1 
HETATM 3846 O O    . HOH D 4 .   ? 6.10712   2.86524   10.26926  1.000 17.26448  ? 400 HOH A O    1 
HETATM 3847 O O    . HOH D 4 .   ? 16.72074  7.99627   9.18237   1.000 44.77586  ? 401 HOH A O    1 
HETATM 3848 O O    . HOH D 4 .   ? 25.21516  -12.92898 12.06917  1.000 23.01437  ? 402 HOH A O    1 
HETATM 3849 O O    . HOH D 4 .   ? 18.01010  -20.38173 16.27457  1.000 46.50160  ? 403 HOH A O    1 
HETATM 3850 O O    . HOH D 4 .   ? 10.90729  7.58071   26.39811  1.000 34.03784  ? 404 HOH A O    1 
HETATM 3851 O O    . HOH D 4 .   ? 16.23670  -17.53969 18.38591  1.000 18.99910  ? 405 HOH A O    1 
HETATM 3852 O O    . HOH D 4 .   ? 22.95338  -16.07500 20.20227  1.000 18.28933  ? 406 HOH A O    1 
HETATM 3853 O O    . HOH D 4 .   ? 4.54707   -14.29291 26.06713  1.000 15.15179  ? 407 HOH A O    1 
HETATM 3854 O O    . HOH D 4 .   ? 27.65190  -2.82629  23.67052  1.000 25.18323  ? 408 HOH A O    1 
HETATM 3855 O O    . HOH D 4 .   ? 9.07072   -23.78546 -4.93676  1.000 33.02407  ? 409 HOH A O    1 
HETATM 3856 O O    . HOH D 4 .   ? 4.12145   -1.44826  29.31408  1.000 33.28464  ? 410 HOH A O    1 
HETATM 3857 O O    . HOH D 4 .   ? 18.16637  -16.78967 24.48562  1.000 24.17309  ? 411 HOH A O    1 
HETATM 3858 O O    . HOH D 4 .   ? 4.70643   -19.86934 26.29219  1.000 15.66940  ? 412 HOH A O    1 
HETATM 3859 O O    . HOH D 4 .   ? 8.53144   -23.23102 18.63995  1.000 13.52517  ? 413 HOH A O    1 
HETATM 3860 O O    . HOH D 4 .   ? 9.37186   4.45208   21.01421  1.000 14.15443  ? 414 HOH A O    1 
HETATM 3861 O O    . HOH D 4 .   ? 3.08817   5.80298   11.29957  1.000 31.94093  ? 415 HOH A O    1 
HETATM 3862 O O    . HOH D 4 .   ? 16.54129  -15.30172 -3.92209  1.000 47.71861  ? 416 HOH A O    1 
HETATM 3863 O O    . HOH D 4 .   ? 15.68571  -3.62690  33.36042  1.000 33.35135  ? 417 HOH A O    1 
HETATM 3864 O O    . HOH D 4 .   ? 1.59876   -24.73049 20.15837  1.000 42.92874  ? 418 HOH A O    1 
HETATM 3865 O O    . HOH D 4 .   ? 29.16278  -6.28372  22.04352  1.000 30.36785  ? 419 HOH A O    1 
HETATM 3866 O O    . HOH D 4 .   ? 18.36622  -1.23163  30.69008  1.000 20.27809  ? 420 HOH A O    1 
HETATM 3867 O O    . HOH D 4 .   ? 24.49949  -6.11919  30.29832  1.000 27.31276  ? 421 HOH A O    1 
HETATM 3868 O O    . HOH D 4 .   ? 20.49885  -12.10389 6.82426   1.000 16.72904  ? 422 HOH A O    1 
HETATM 3869 O O    . HOH D 4 .   ? -2.33552  -18.33780 28.38413  1.000 41.50000  ? 423 HOH A O    1 
HETATM 3870 O O    . HOH D 4 .   ? 0.28821   -10.77541 5.89167   1.000 15.34781  ? 424 HOH A O    1 
HETATM 3871 O O    . HOH D 4 .   ? -0.66801  -0.78855  10.83072  1.000 25.49155  ? 425 HOH A O    1 
HETATM 3872 O O    . HOH D 4 .   ? -1.68144  -20.13588 7.38046   1.000 15.28046  ? 426 HOH A O    1 
HETATM 3873 O O    . HOH D 4 .   ? -9.07357  -5.05480  -2.86983  1.000 37.83661  ? 427 HOH A O    1 
HETATM 3874 O O    . HOH D 4 .   ? -1.14912  -8.59852  6.78272   1.000 17.84786  ? 428 HOH A O    1 
HETATM 3875 O O    . HOH D 4 .   ? -8.52687  -9.06373  25.40970  1.000 33.42696  ? 429 HOH A O    1 
HETATM 3876 O O    . HOH D 4 .   ? 8.64911   -27.27201 1.57284   1.000 29.82813  ? 430 HOH A O    1 
HETATM 3877 O O    . HOH D 4 .   ? -5.97991  -15.61069 25.85405  1.000 27.88076  ? 431 HOH A O    1 
HETATM 3878 O O    . HOH D 4 .   ? 17.54566  -13.99709 34.71653  1.000 59.72005  ? 432 HOH A O    1 
HETATM 3879 O O    . HOH D 4 .   ? 1.12322   -15.15778 -8.50279  1.000 37.53957  ? 433 HOH A O    1 
HETATM 3880 O O    . HOH D 4 .   ? -5.13718  9.26301   20.94332  1.000 42.24077  ? 434 HOH A O    1 
HETATM 3881 O O    . HOH D 4 .   ? -2.44716  1.70322   12.49080  1.000 21.03215  ? 435 HOH A O    1 
HETATM 3882 O O    . HOH D 4 .   ? 22.35238  -2.00873  8.67662   1.000 18.90420  ? 436 HOH A O    1 
HETATM 3883 O O    . HOH D 4 .   ? -12.24834 -15.35425 9.72312   1.000 48.39507  ? 437 HOH A O    1 
HETATM 3884 O O    . HOH D 4 .   ? 15.30116  2.03446   7.12663   1.000 21.29561  ? 438 HOH A O    1 
HETATM 3885 O O    . HOH D 4 .   ? -8.50695  -16.67875 22.98345  1.000 35.67559  ? 439 HOH A O    1 
HETATM 3886 O O    . HOH D 4 .   ? 12.12414  -23.59524 -4.41636  1.000 43.31858  ? 440 HOH A O    1 
HETATM 3887 O O    . HOH D 4 .   ? 9.37213   -27.33947 13.84581  1.000 15.69700  ? 441 HOH A O    1 
HETATM 3888 O O    . HOH D 4 .   ? 12.09806  -0.83803  25.15039  1.000 14.51726  ? 442 HOH A O    1 
HETATM 3889 O O    . HOH D 4 .   ? 24.26196  1.61866   27.59600  1.000 22.34868  ? 443 HOH A O    1 
HETATM 3890 O O    . HOH D 4 .   ? -3.32011  -21.93358 8.78609   1.000 26.95937  ? 444 HOH A O    1 
HETATM 3891 O O    . HOH D 4 .   ? -0.89653  -20.60242 24.89617  1.000 27.74354  ? 445 HOH A O    1 
HETATM 3892 O O    . HOH D 4 .   ? 19.81434  0.99427   5.60288   1.000 25.58230  ? 446 HOH A O    1 
HETATM 3893 O O    . HOH D 4 .   ? 12.68350  -12.95820 33.71860  1.000 53.25363  ? 447 HOH A O    1 
HETATM 3894 O O    . HOH D 4 .   ? -7.42043  -20.47998 13.76785  1.000 20.98004  ? 448 HOH A O    1 
HETATM 3895 O O    . HOH D 4 .   ? -0.18611  -26.02229 20.28913  1.000 48.18045  ? 449 HOH A O    1 
HETATM 3896 O O    . HOH D 4 .   ? 13.89695  -6.40002  0.20055   1.000 22.17672  ? 450 HOH A O    1 
HETATM 3897 O O    . HOH D 4 .   ? 3.42089   0.73761   27.88569  1.000 44.09464  ? 451 HOH A O    1 
HETATM 3898 O O    . HOH D 4 .   ? -2.03643  -23.77101 2.01468   1.000 27.34904  ? 452 HOH A O    1 
HETATM 3899 O O    . HOH D 4 .   ? 18.99117  -13.51142 -0.89771  1.000 41.38195  ? 453 HOH A O    1 
HETATM 3900 O O    . HOH D 4 .   ? -3.33557  10.23559  23.12141  1.000 58.86776  ? 454 HOH A O    1 
HETATM 3901 O O    . HOH D 4 .   ? -1.76151  -25.78315 8.91112   1.000 26.49618  ? 455 HOH A O    1 
HETATM 3902 O O    . HOH D 4 .   ? 27.54216  -11.15962 4.26675   1.000 47.40398  ? 456 HOH A O    1 
HETATM 3903 O O    . HOH D 4 .   ? 18.48704  -17.10437 -0.73502  1.000 39.42320  ? 457 HOH A O    1 
HETATM 3904 O O    . HOH D 4 .   ? 0.74661   -17.23481 0.17391   1.000 53.57578  ? 458 HOH A O    1 
HETATM 3905 O O    . HOH D 4 .   ? -13.41027 -9.37165  15.25316  1.000 21.41413  ? 459 HOH A O    1 
HETATM 3906 O O    . HOH D 4 .   ? 10.98280  -12.81411 11.74402  1.000 30.27833  ? 460 HOH A O    1 
HETATM 3907 O O    . HOH D 4 .   ? -12.03288 -18.55642 22.39151  1.000 58.50573  ? 461 HOH A O    1 
HETATM 3908 O O    . HOH D 4 .   ? 1.40342   -28.53768 2.66225   1.000 43.79429  ? 462 HOH A O    1 
HETATM 3909 O O    . HOH D 4 .   ? 22.62574  -2.34777  21.10568  1.000 13.46028  ? 463 HOH A O    1 
HETATM 3910 O O    . HOH D 4 .   ? 16.30154  -12.48016 -4.50241  1.000 53.67940  ? 464 HOH A O    1 
HETATM 3911 O O    . HOH D 4 .   ? -9.54570  -14.29509 5.70305   1.000 36.38516  ? 465 HOH A O    1 
HETATM 3912 O O    . HOH D 4 .   ? 3.53185   -18.90119 30.89914  1.000 27.36580  ? 466 HOH A O    1 
HETATM 3913 O O    . HOH D 4 .   ? 23.41854  -16.24091 24.82232  1.000 48.21402  ? 467 HOH A O    1 
HETATM 3914 O O    . HOH D 4 .   ? 2.65447   -17.97094 -8.79291  1.000 53.34710  ? 468 HOH A O    1 
HETATM 3915 O O    . HOH D 4 .   ? 2.88424   -3.38054  28.21703  1.000 28.50367  ? 469 HOH A O    1 
HETATM 3916 O O    . HOH D 4 .   ? -17.14819 -17.19647 19.95137  1.000 20.31236  ? 470 HOH A O    1 
HETATM 3917 O O    . HOH D 4 .   ? 9.64950   -17.12662 30.57423  1.000 23.61139  ? 471 HOH A O    1 
HETATM 3918 O O    . HOH D 4 .   ? -0.43546  -12.39049 31.65048  1.000 35.58732  ? 472 HOH A O    1 
HETATM 3919 O O    . HOH D 4 .   ? -1.14712  -5.75114  -1.04933  1.000 42.22616  ? 473 HOH A O    1 
HETATM 3920 O O    . HOH D 4 .   ? -12.74690 -7.61312  17.49926  1.000 30.46570  ? 474 HOH A O    1 
HETATM 3921 O O    . HOH D 4 .   ? 9.95345   -23.87889 23.50162  1.000 52.52962  ? 475 HOH A O    1 
HETATM 3922 O O    . HOH D 4 .   ? 15.82861  6.26809   6.54538   1.000 42.47693  ? 476 HOH A O    1 
HETATM 3923 O O    . HOH D 4 .   ? 25.71537  -15.23381 8.64956   1.000 49.50858  ? 477 HOH A O    1 
HETATM 3924 O O    . HOH D 4 .   ? -3.53024  0.08433   30.72216  1.000 45.39675  ? 478 HOH A O    1 
HETATM 3925 O O    . HOH D 4 .   ? 2.16745   -8.50239  31.99284  1.000 28.08203  ? 479 HOH A O    1 
HETATM 3926 O O    . HOH D 4 .   ? -3.40170  -21.52194 23.38575  1.000 31.67801  ? 480 HOH A O    1 
HETATM 3927 O O    . HOH D 4 .   ? -4.06406  -11.09679 -5.56190  1.000 25.36944  ? 481 HOH A O    1 
HETATM 3928 O O    . HOH D 4 .   ? 4.83282   -12.68805 -7.29495  1.000 51.20226  ? 482 HOH A O    1 
HETATM 3929 O O    . HOH D 4 .   ? -13.97132 -9.07238  2.62352   1.000 47.06484  ? 483 HOH A O    1 
HETATM 3930 O O    . HOH D 4 .   ? -7.81896  -6.18229  18.83822  1.000 20.67076  ? 484 HOH A O    1 
HETATM 3931 O O    . HOH D 4 .   ? 3.10270   -26.50902 22.38246  1.000 41.73988  ? 485 HOH A O    1 
HETATM 3932 O O    . HOH D 4 .   ? 21.94963  5.57876   15.11730  1.000 42.43904  ? 486 HOH A O    1 
HETATM 3933 O O    . HOH D 4 .   ? 10.84619  -9.07313  -6.97401  1.000 42.73554  ? 487 HOH A O    1 
HETATM 3934 O O    . HOH D 4 .   ? 0.18639   -18.81011 -2.03849  1.000 20.36315  ? 488 HOH A O    1 
HETATM 3935 O O    . HOH D 4 .   ? -8.25369  -1.86996  16.59560  1.000 42.61173  ? 489 HOH A O    1 
HETATM 3936 O O    . HOH D 4 .   ? 19.04104  -14.70706 20.36783  1.000 16.71011  ? 490 HOH A O    1 
HETATM 3937 O O    . HOH D 4 .   ? 19.67228  -9.80581  -1.23313  1.000 30.39456  ? 491 HOH A O    1 
HETATM 3938 O O    . HOH D 4 .   ? 12.93323  -16.99677 -7.23715  1.000 45.13350  ? 492 HOH A O    1 
HETATM 3939 O O    . HOH D 4 .   ? -4.65996  -13.84703 -5.04854  1.000 22.86109  ? 493 HOH A O    1 
HETATM 3940 O O    . HOH D 4 .   ? 12.53569  -20.90439 18.67211  1.000 20.08964  ? 494 HOH A O    1 
HETATM 3941 O O    . HOH D 4 .   ? 0.07859   -17.49410 31.25753  1.000 32.43669  ? 495 HOH A O    1 
HETATM 3942 O O    . HOH D 4 .   ? 27.01757  -11.92322 27.45026  1.000 29.67150  ? 496 HOH A O    1 
HETATM 3943 O O    . HOH D 4 .   ? 17.31809  -15.67193 4.86827   1.000 32.89045  ? 497 HOH A O    1 
HETATM 3944 O O    . HOH D 4 .   ? -12.66224 -15.44976 23.55795  1.000 43.57517  ? 498 HOH A O    1 
HETATM 3945 O O    . HOH D 4 .   ? 25.60592  -5.57338  0.63320   1.000 33.43146  ? 499 HOH A O    1 
HETATM 3946 O O    . HOH D 4 .   ? 6.91280   5.75168   21.04905  1.000 17.80939  ? 500 HOH A O    1 
HETATM 3947 O O    . HOH D 4 .   ? -2.99391  -23.68072 17.66479  1.000 43.99680  ? 501 HOH A O    1 
HETATM 3948 O O    . HOH D 4 .   ? -4.07537  -21.01473 1.30648   1.000 26.11177  ? 502 HOH A O    1 
HETATM 3949 O O    . HOH D 4 .   ? 25.21549  -0.89991  27.84413  1.000 18.91696  ? 503 HOH A O    1 
HETATM 3950 O O    . HOH D 4 .   ? 13.04262  4.20450   29.41220  1.000 34.40282  ? 504 HOH A O    1 
HETATM 3951 O O    . HOH D 4 .   ? 24.36146  -5.44886  -1.93206  1.000 44.10797  ? 505 HOH A O    1 
HETATM 3952 O O    . HOH D 4 .   ? 28.55006  -8.30722  24.12983  1.000 34.37375  ? 506 HOH A O    1 
HETATM 3953 O O    . HOH D 4 .   ? -10.17099 -9.53424  9.61819   1.000 67.74155  ? 507 HOH A O    1 
HETATM 3954 O O    . HOH D 4 .   ? 1.67664   3.86308   27.36879  1.000 28.51363  ? 508 HOH A O    1 
HETATM 3955 O O    . HOH D 4 .   ? -8.71894  -6.68724  26.50098  1.000 48.44343  ? 509 HOH A O    1 
HETATM 3956 O O    . HOH D 4 .   ? -7.70709  -1.24764  24.84965  1.000 45.23715  ? 510 HOH A O    1 
HETATM 3957 O O    . HOH D 4 .   ? -3.94385  -5.62708  10.68858  1.000 35.86834  ? 511 HOH A O    1 
HETATM 3958 O O    . HOH D 4 .   ? 6.90899   4.18077   7.65570   1.000 31.96992  ? 512 HOH A O    1 
HETATM 3959 O O    . HOH D 4 .   ? -13.31389 -12.08424 0.13959   1.000 49.73471  ? 513 HOH A O    1 
HETATM 3960 O O    . HOH D 4 .   ? -0.86732  -30.29616 11.43444  1.000 54.53905  ? 514 HOH A O    1 
HETATM 3961 O O    . HOH D 4 .   ? 2.53911   -15.25907 24.29178  1.000 14.10382  ? 515 HOH A O    1 
HETATM 3962 O O    . HOH D 4 .   ? 8.89715   -21.75402 25.27765  1.000 41.59966  ? 516 HOH A O    1 
HETATM 3963 O O    . HOH D 4 .   ? 0.94600   7.87075   13.66390  1.000 46.36724  ? 517 HOH A O    1 
HETATM 3964 O O    . HOH D 4 .   ? 11.42870  7.77661   23.05805  1.000 33.57844  ? 518 HOH A O    1 
HETATM 3965 O O    . HOH D 4 .   ? 20.72721  -14.61244 13.65563  1.000 27.28695  ? 519 HOH A O    1 
HETATM 3966 O O    . HOH D 4 .   ? -2.62907  -8.12831  26.90574  1.000 24.17740  ? 520 HOH A O    1 
HETATM 3967 O O    . HOH D 4 .   ? 5.76191   -3.70395  2.27846   1.000 49.76939  ? 521 HOH A O    1 
HETATM 3968 O O    . HOH D 4 .   ? 17.15402  -19.26422 13.19540  1.000 59.71655  ? 522 HOH A O    1 
HETATM 3969 O O    . HOH D 4 .   ? 25.84925  -1.61725  9.16089   1.000 21.66189  ? 523 HOH A O    1 
HETATM 3970 O O    . HOH D 4 .   ? 1.53282   -23.13242 23.42604  1.000 41.58377  ? 524 HOH A O    1 
HETATM 3971 O O    . HOH D 4 .   ? 6.05593   7.56805   18.97529  1.000 54.08211  ? 525 HOH A O    1 
HETATM 3972 O O    . HOH D 4 .   ? -18.25733 -19.24671 18.46840  1.000 43.01442  ? 526 HOH A O    1 
HETATM 3973 O O    . HOH D 4 .   ? -9.42126  -7.49644  8.92755   1.000 56.44839  ? 527 HOH A O    1 
HETATM 3974 O O    . HOH D 4 .   ? 21.36258  -12.71204 29.67648  1.000 24.63432  ? 528 HOH A O    1 
HETATM 3975 O O    . HOH D 4 .   ? 8.27736   -24.77455 5.32090   1.000 32.50251  ? 529 HOH A O    1 
HETATM 3976 O O    . HOH D 4 .   ? 1.80528   -3.14536  1.32152   1.000 46.31004  ? 530 HOH A O    1 
HETATM 3977 O O    . HOH D 4 .   ? 23.63047  -0.96019  4.70364   1.000 46.76115  ? 531 HOH A O    1 
HETATM 3978 O O    . HOH D 4 .   ? -9.95310  -20.25759 12.67793  1.000 33.39523  ? 532 HOH A O    1 
HETATM 3979 O O    . HOH D 4 .   ? 16.18749  -23.79537 14.28675  1.000 58.70199  ? 533 HOH A O    1 
HETATM 3980 O O    . HOH D 4 .   ? 27.96352  -9.79923  29.00431  1.000 47.55274  ? 534 HOH A O    1 
HETATM 3981 O O    . HOH D 4 .   ? -6.81982  -7.83145  11.78845  1.000 60.12069  ? 535 HOH A O    1 
HETATM 3982 O O    . HOH D 4 .   ? -8.33509  -20.18843 22.79507  1.000 48.40721  ? 536 HOH A O    1 
HETATM 3983 O O    . HOH D 4 .   ? -10.16919 5.62725   18.89500  1.000 54.50898  ? 537 HOH A O    1 
HETATM 3984 O O    . HOH D 4 .   ? -0.90595  -27.43642 12.08586  1.000 54.33864  ? 538 HOH A O    1 
HETATM 3985 O O    . HOH D 4 .   ? -7.00231  -20.93004 9.59024   1.000 51.79059  ? 539 HOH A O    1 
HETATM 3986 O O    . HOH D 4 .   ? 31.93973  -12.91147 9.61693   1.000 45.72402  ? 540 HOH A O    1 
HETATM 3987 O O    . HOH D 4 .   ? 14.45000  -19.21853 19.95686  1.000 33.27044  ? 541 HOH A O    1 
HETATM 3988 O O    . HOH D 4 .   ? -9.49045  -9.59805  6.76659   1.000 43.71274  ? 542 HOH A O    1 
HETATM 3989 O O    . HOH D 4 .   ? -8.77259  -15.83818 26.18988  1.000 75.98819  ? 543 HOH A O    1 
HETATM 3990 O O    . HOH D 4 .   ? 2.13108   -11.15335 31.65515  1.000 30.90884  ? 544 HOH A O    1 
HETATM 3991 O O    . HOH D 4 .   ? 19.60353  -15.48183 3.61849   1.000 36.03455  ? 545 HOH A O    1 
HETATM 3992 O O    . HOH D 4 .   ? -13.78142 -13.64811 10.37270  1.000 54.54600  ? 546 HOH A O    1 
HETATM 3993 O O    . HOH D 4 .   ? 17.46329  2.74243   5.65688   1.000 40.34287  ? 547 HOH A O    1 
HETATM 3994 O O    . HOH D 4 .   ? -1.62395  -30.59600 18.73461  1.000 35.48218  ? 548 HOH A O    1 
HETATM 3995 O O    . HOH D 4 .   ? -0.39989  -4.60573  1.37622   1.000 44.72750  ? 549 HOH A O    1 
HETATM 3996 O O    . HOH D 4 .   ? 8.47825   -26.14430 24.38219  1.000 26.95228  ? 550 HOH A O    1 
HETATM 3997 O O    . HOH D 4 .   ? -11.37750 -6.17676  -2.68343  1.000 42.59756  ? 551 HOH A O    1 
HETATM 3998 O O    . HOH D 4 .   ? -2.31734  -29.22060 16.97680  1.000 46.81319  ? 552 HOH A O    1 
HETATM 3999 O O    . HOH D 4 .   ? 16.19045  -15.46542 -6.61967  1.000 45.57487  ? 553 HOH A O    1 
HETATM 4000 O O    . HOH D 4 .   ? 12.10666  -4.50564  -0.83207  1.000 32.17420  ? 554 HOH A O    1 
HETATM 4001 O O    . HOH D 4 .   ? 2.57310   -11.81781 -7.41352  1.000 51.29707  ? 555 HOH A O    1 
HETATM 4002 O O    . HOH D 4 .   ? 10.91159  -2.83287  1.12664   1.000 37.32882  ? 556 HOH A O    1 
HETATM 4003 O O    . HOH D 4 .   ? 14.25656  -1.86938  32.64734  1.000 52.70339  ? 557 HOH A O    1 
HETATM 4004 O O    . HOH D 4 .   ? 16.36739  -0.19479  32.54789  1.000 41.74050  ? 558 HOH A O    1 
HETATM 4005 O O    . HOH D 4 .   ? -2.36497  -19.49064 -3.00617  1.000 27.41975  ? 559 HOH A O    1 
HETATM 4006 O O    . HOH D 4 .   ? 3.93036   5.17649   9.05402   1.000 57.41778  ? 560 HOH A O    1 
HETATM 4007 O O    . HOH D 4 .   ? -10.10355 -12.35832 6.87350   1.000 68.99238  ? 561 HOH A O    1 
HETATM 4008 O O    . HOH D 4 .   ? 32.27686  -8.23576  4.97571   1.000 52.66961  ? 562 HOH A O    1 
HETATM 4009 O O    . HOH D 4 .   ? -13.79122 -22.42180 13.99333  1.000 50.91464  ? 563 HOH A O    1 
HETATM 4010 O O    . HOH D 4 .   ? 15.84363  -6.72420  -2.20316  1.000 57.02845  ? 564 HOH A O    1 
HETATM 4011 O O    . HOH D 4 .   ? 26.45871  -8.11318  30.87548  1.000 50.51633  ? 565 HOH A O    1 
HETATM 4012 O O    . HOH D 4 .   ? -0.48167  -28.17891 22.11337  1.000 56.07241  ? 566 HOH A O    1 
HETATM 4013 O O    . HOH D 4 .   ? 10.56427  -24.63344 17.58664  1.000 17.82397  ? 567 HOH A O    1 
HETATM 4014 O O    . HOH D 4 .   ? 6.57867   -25.05195 25.63888  1.000 50.74612  ? 568 HOH A O    1 
HETATM 4015 O O    . HOH D 4 .   ? 19.22293  -14.13736 -3.52375  1.000 66.71226  ? 569 HOH A O    1 
HETATM 4016 O O    . HOH D 4 .   ? 4.12633   -21.76158 28.09678  1.000 45.46262  ? 570 HOH A O    1 
HETATM 4017 O O    . HOH D 4 .   ? 29.28079  -4.47835  10.95950  1.000 42.60067  ? 571 HOH A O    1 
HETATM 4018 O O    . HOH D 4 .   ? 21.36833  -16.25598 17.93202  1.000 17.44454  ? 572 HOH A O    1 
HETATM 4019 O O    . HOH D 4 .   ? -2.32253  -2.91397  31.68831  1.000 51.90650  ? 573 HOH A O    1 
HETATM 4020 O O    . HOH D 4 .   ? -20.27270 -15.90653 13.22531  1.000 54.45625  ? 574 HOH A O    1 
HETATM 4021 O O    . HOH D 4 .   ? 8.37779   4.92977   25.35656  1.000 33.24056  ? 575 HOH A O    1 
HETATM 4022 O O    . HOH D 4 .   ? 13.01197  -21.04596 23.35080  1.000 52.24405  ? 576 HOH A O    1 
HETATM 4023 O O    . HOH D 4 .   ? 21.52175  -13.98937 5.07291   1.000 25.25443  ? 577 HOH A O    1 
HETATM 4024 O O    . HOH D 4 .   ? 16.06683  -18.24207 25.42848  1.000 48.55101  ? 578 HOH A O    1 
HETATM 4025 O O    . HOH D 4 .   ? 0.17788   -10.27341 35.33630  1.000 51.49785  ? 579 HOH A O    1 
HETATM 4026 O O    . HOH D 4 .   ? 12.22629  -4.28676  -3.42427  1.000 42.45021  ? 580 HOH A O    1 
HETATM 4027 O O    . HOH D 4 .   ? 6.29365   -9.84855  31.10720  1.000 21.73749  ? 581 HOH A O    1 
HETATM 4028 O O    . HOH D 4 .   ? -3.95041  -21.01198 -1.39783  1.000 31.11219  ? 582 HOH A O    1 
HETATM 4029 O O    . HOH D 4 .   ? 31.61657  -7.13494  10.05146  1.000 54.48726  ? 583 HOH A O    1 
HETATM 4030 O O    . HOH D 4 .   ? 18.97124  -17.35820 19.12775  1.000 22.41384  ? 584 HOH A O    1 
HETATM 4031 O O    . HOH D 4 .   ? -2.40612  -25.09407 4.44686   1.000 42.86495  ? 585 HOH A O    1 
HETATM 4032 O O    . HOH D 4 .   ? -7.86828  -4.98302  16.37815  1.000 49.96738  ? 586 HOH A O    1 
HETATM 4033 O O    . HOH D 4 .   ? -8.95561  -18.99608 5.18822   1.000 46.80119  ? 587 HOH A O    1 
HETATM 4034 O O    . HOH D 4 .   ? 15.42766  -1.89940  -0.15318  1.000 46.27494  ? 588 HOH A O    1 
HETATM 4035 O O    . HOH D 4 .   ? 8.82798   -0.94312  0.40681   1.000 42.55235  ? 589 HOH A O    1 
HETATM 4036 O O    . HOH D 4 .   ? -0.98582  -30.87178 21.00867  1.000 51.21855  ? 590 HOH A O    1 
HETATM 4037 O O    . HOH D 4 .   ? 19.96831  -17.20340 26.26779  1.000 46.83696  ? 591 HOH A O    1 
HETATM 4038 O O    . HOH D 4 .   ? -6.44696  -17.21568 -4.10426  1.000 48.91612  ? 592 HOH A O    1 
HETATM 4039 O O    . HOH D 4 .   ? 22.07770  -17.64548 22.23699  1.000 27.45200  ? 593 HOH A O    1 
HETATM 4040 O O    . HOH D 4 .   ? 25.12184  -4.49242  32.03274  1.000 48.12997  ? 594 HOH A O    1 
HETATM 4041 O O    . HOH D 4 .   ? 18.35823  -16.25916 30.51991  1.000 30.66339  ? 595 HOH A O    1 
HETATM 4042 O O    . HOH D 4 .   ? 13.03985  9.12491   11.40313  1.000 57.50050  ? 596 HOH A O    1 
HETATM 4043 O O    . HOH D 4 .   ? 19.11853  -15.23689 0.93868   1.000 38.00745  ? 597 HOH A O    1 
HETATM 4044 O O    . HOH D 4 .   ? -5.88009  -22.36279 7.54643   1.000 55.46410  ? 598 HOH A O    1 
HETATM 4045 O O    . HOH D 4 .   ? 18.39765  -3.14231  34.03421  1.000 49.18673  ? 599 HOH A O    1 
HETATM 4046 O O    . HOH D 4 .   ? -8.42031  -19.15356 0.00459   1.000 58.33974  ? 600 HOH A O    1 
HETATM 4047 O O    . HOH D 4 .   ? 5.77512   0.63278   31.31001  1.000 37.07937  ? 601 HOH A O    1 
HETATM 4048 O O    . HOH D 4 .   ? 23.96622  4.80335   8.82481   1.000 49.41357  ? 602 HOH A O    1 
HETATM 4049 O O    . HOH D 4 .   ? 16.57888  -15.44326 28.62457  1.000 26.78044  ? 603 HOH A O    1 
HETATM 4050 O O    . HOH D 4 .   ? 21.29569  -11.43682 -0.83630  1.000 48.57113  ? 604 HOH A O    1 
HETATM 4051 O O    . HOH D 4 .   ? 4.44794   9.37951   20.07980  1.000 55.58217  ? 605 HOH A O    1 
HETATM 4052 O O    . HOH D 4 .   ? 19.46155  -17.24273 21.92636  1.000 36.27025  ? 606 HOH A O    1 
HETATM 4053 O O    . HOH D 4 .   ? -2.36379  -20.75339 27.35732  1.000 42.84159  ? 607 HOH A O    1 
HETATM 4054 O O    . HOH D 4 .   ? -1.26795  -23.30467 22.65686  1.000 56.37110  ? 608 HOH A O    1 
HETATM 4055 O O    . HOH D 4 .   ? 26.21465  -1.83346  30.23249  1.000 41.31146  ? 609 HOH A O    1 
HETATM 4056 O O    . HOH D 4 .   ? 12.10216  -24.00938 24.03866  1.000 53.35373  ? 610 HOH A O    1 
HETATM 4057 O O    . HOH D 4 .   ? 13.98810  -16.60928 28.72294  1.000 25.16411  ? 611 HOH A O    1 
HETATM 4058 O O    . HOH D 4 .   ? 15.28079  -19.79188 22.68547  1.000 47.00581  ? 612 HOH A O    1 
HETATM 4059 O O    . HOH D 4 .   ? 30.38008  -3.67578  13.31276  1.000 38.82307  ? 613 HOH A O    1 
HETATM 4060 O O    . HOH D 4 .   ? 23.54264  2.48399   7.15366   1.000 30.98212  ? 614 HOH A O    1 
HETATM 4061 O O    . HOH D 4 .   ? 10.48262  -3.33883  36.26499  1.000 48.33190  ? 615 HOH A O    1 
HETATM 4062 O O    . HOH D 4 .   ? -3.09688  -17.40881 -6.74432  1.000 43.94544  ? 616 HOH A O    1 
HETATM 4063 O O    . HOH D 4 .   ? 27.11916  -0.97209  25.62686  1.000 35.10476  ? 617 HOH A O    1 
HETATM 4064 O O    . HOH D 4 .   ? 32.27762  -15.20537 8.94401   1.000 47.46406  ? 618 HOH A O    1 
HETATM 4065 O O    . HOH D 4 .   ? 8.32351   -17.43385 33.26425  1.000 46.68299  ? 619 HOH A O    1 
HETATM 4066 O O    . HOH D 4 .   ? 20.47757  -19.54939 15.68436  1.000 53.35832  ? 620 HOH A O    1 
HETATM 4067 O O    . HOH D 4 .   ? 13.48839  -23.97025 21.47989  1.000 44.85296  ? 621 HOH A O    1 
HETATM 4068 O O    . HOH D 4 .   ? 21.84320  0.34220   7.25716   1.000 25.67488  ? 622 HOH A O    1 
HETATM 4069 O O    . HOH D 4 .   ? 31.30728  -6.09252  13.75147  1.000 47.51695  ? 623 HOH A O    1 
HETATM 4070 O O    . HOH D 4 .   ? 29.37180  -10.42894 30.19907  1.000 59.50979  ? 624 HOH A O    1 
HETATM 4071 O O    . HOH D 4 .   ? -4.39039  -14.76934 -7.59716  1.000 25.63954  ? 625 HOH A O    1 
HETATM 4072 O O    . HOH D 4 .   ? -0.05966  -12.67231 -9.49623  1.000 47.90528  ? 626 HOH A O    1 
HETATM 4073 O O    . HOH D 4 .   ? 31.48522  -4.99646  22.58032  1.000 45.84370  ? 627 HOH A O    1 
HETATM 4074 O O    . HOH D 4 .   ? 1.94764   -11.99016 33.90763  1.000 58.72363  ? 628 HOH A O    1 
HETATM 4075 O O    . HOH D 4 .   ? 4.76180   -8.92500  33.13422  1.000 55.52842  ? 629 HOH A O    1 
HETATM 4076 O O    . HOH D 4 .   ? -6.79187  -20.47335 1.80727   1.000 45.58606  ? 630 HOH A O    1 
HETATM 4077 O O    . HOH D 4 .   ? 27.43758  -7.84467  0.33255   1.000 53.64994  ? 631 HOH A O    1 
HETATM 4078 O O    . HOH D 4 .   ? -2.45827  -25.03600 24.96879  1.000 57.91179  ? 632 HOH A O    1 
HETATM 4079 O O    . HOH D 4 .   ? 34.09649  -16.64364 7.18037   1.000 23.10547  ? 633 HOH A O    1 
HETATM 4080 O O    . HOH D 4 .   ? 12.69312  5.19815   1.27308   1.000 48.77501  ? 634 HOH A O    1 
HETATM 4081 O O    . HOH D 4 .   ? 7.35499   0.90364   35.22830  1.000 51.72015  ? 635 HOH A O    1 
HETATM 4082 O O    . HOH D 4 .   ? -3.87914  -16.75197 -10.98035 1.000 52.28594  ? 636 HOH A O    1 
HETATM 4083 O O    . HOH D 4 .   ? 8.45380   -2.54150  39.48939  1.000 59.86781  ? 637 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . GLU A 1   ? 0.60781 0.45243 0.65918 0.02463  0.20741  0.06321  15  GLU A N   
2    C CA  . GLU A 1   ? 0.59837 0.45099 0.64790 0.02110  0.19365  0.05817  15  GLU A CA  
3    C C   . GLU A 1   ? 0.51443 0.40405 0.51982 0.02441  0.11012  0.04951  15  GLU A C   
4    O O   . GLU A 1   ? 0.51309 0.40245 0.51935 0.03761  0.10928  0.05506  15  GLU A O   
5    C CB  . GLU A 1   ? 0.66364 0.49174 0.75515 0.01337  0.24876  0.05916  15  GLU A CB  
6    C CG  . GLU A 1   ? 0.71609 0.52637 0.84562 0.00948  0.28901  0.06164  15  GLU A CG  
7    C CD  . GLU A 1   ? 0.75551 0.55225 0.91022 0.00390  0.31707  0.06536  15  GLU A CD  
8    O OE1 . GLU A 1   ? 0.76754 0.55889 0.92752 0.00275  0.32527  0.06978  15  GLU A OE1 
9    O OE2 . GLU A 1   ? 0.77066 0.56272 0.93485 0.00142  0.32443  0.06359  15  GLU A OE2 
10   N N   . PHE A 2   ? 0.43425 0.36011 0.38575 0.01478  0.00987  0.03369  16  PHE A N   
11   C CA  . PHE A 2   ? 0.35213 0.31063 0.27941 0.00741  -0.08159 0.01275  16  PHE A CA  
12   C C   . PHE A 2   ? 0.29909 0.26166 0.25530 -0.00535 -0.08153 0.00275  16  PHE A C   
13   O O   . PHE A 2   ? 0.32242 0.26937 0.25537 -0.00985 -0.06044 0.01927  16  PHE A O   
14   C CB  . PHE A 2   ? 0.33858 0.31407 0.26902 0.01322  -0.12854 0.01719  16  PHE A CB  
15   C CG  . PHE A 2   ? 0.33244 0.31634 0.29197 0.01538  -0.14964 0.02295  16  PHE A CG  
16   C CD1 . PHE A 2   ? 0.34085 0.31387 0.29807 0.00836  -0.14534 0.01942  16  PHE A CD1 
17   C CD2 . PHE A 2   ? 0.33824 0.32440 0.31462 0.02318  -0.14713 0.03274  16  PHE A CD2 
18   C CE1 . PHE A 2   ? 0.34693 0.32158 0.29455 0.00049  -0.14374 0.01999  16  PHE A CE1 
19   C CE2 . PHE A 2   ? 0.34974 0.33192 0.32395 0.01288  -0.14041 0.01908  16  PHE A CE2 
20   C CZ  . PHE A 2   ? 0.35296 0.32902 0.31705 0.00683  -0.13739 0.01624  16  PHE A CZ  
21   N N   . LEU A 3   ? 0.22913 0.21481 0.25384 -0.00480 -0.08972 0.00395  17  LEU A N   
22   C CA  . LEU A 3   ? 0.20306 0.20603 0.25389 0.00027  -0.07899 0.00355  17  LEU A CA  
23   C C   . LEU A 3   ? 0.17462 0.17915 0.24166 -0.01935 -0.09629 0.00368  17  LEU A C   
24   O O   . LEU A 3   ? 0.18570 0.17742 0.28231 -0.02519 -0.06614 -0.00227 17  LEU A O   
25   C CB  . LEU A 3   ? 0.22249 0.22549 0.25578 0.01559  -0.06524 0.03063  17  LEU A CB  
26   C CG  . LEU A 3   ? 0.21964 0.24930 0.26318 0.01045  -0.08998 0.04417  17  LEU A CG  
27   C CD1 . LEU A 3   ? 0.22635 0.27380 0.27991 0.00805  -0.07552 0.05115  17  LEU A CD1 
28   C CD2 . LEU A 3   ? 0.23094 0.26075 0.29000 0.01099  -0.08317 0.05488  17  LEU A CD2 
29   N N   . THR A 4   ? 0.17360 0.16049 0.22084 -0.02412 -0.08438 -0.00214 18  THR A N   
30   C CA  . THR A 4   ? 0.18613 0.16127 0.19890 -0.01419 -0.09432 0.00865  18  THR A CA  
31   C C   . THR A 4   ? 0.15878 0.15360 0.17808 -0.01296 -0.09988 0.01027  18  THR A C   
32   O O   . THR A 4   ? 0.15395 0.15602 0.19592 -0.01279 -0.10075 0.01912  18  THR A O   
33   C CB  . THR A 4   ? 0.23065 0.18011 0.20547 -0.01444 -0.09968 0.00847  18  THR A CB  
34   O OG1 . THR A 4   ? 0.27830 0.20189 0.21361 0.00628  -0.09923 0.00324  18  THR A OG1 
35   C CG2 . THR A 4   ? 0.23757 0.18544 0.22736 -0.00303 -0.10401 0.02557  18  THR A CG2 
43   N N   . ALA A 5   ? 0.14537 0.14989 0.19534 -0.00925 -0.09840 0.00118  19  ALA A N   
44   C CA  . ALA A 5   ? 0.13826 0.15064 0.22238 -0.00751 -0.08109 0.00664  19  ALA A CA  
45   C C   . ALA A 5   ? 0.11850 0.14887 0.20700 -0.00713 -0.08651 0.01046  19  ALA A C   
46   O O   . ALA A 5   ? 0.13575 0.16010 0.20209 -0.00692 -0.09495 0.01533  19  ALA A O   
47   C CB  . ALA A 5   ? 0.13562 0.15497 0.22652 -0.03294 -0.07101 -0.00182 19  ALA A CB  
53   N N   . VAL A 6   ? 0.11277 0.13769 0.20046 -0.00888 -0.08224 0.01581  20  VAL A N   
54   C CA  . VAL A 6   ? 0.11970 0.14451 0.20329 -0.00277 -0.06964 0.02058  20  VAL A CA  
55   C C   . VAL A 6   ? 0.12482 0.15039 0.18609 -0.00968 -0.06985 0.01520  20  VAL A C   
56   O O   . VAL A 6   ? 0.13426 0.14742 0.20227 0.00061  -0.07187 0.01707  20  VAL A O   
57   C CB  . VAL A 6   ? 0.11099 0.15696 0.17916 0.00239  -0.06913 0.01023  20  VAL A CB  
58   C CG1 . VAL A 6   ? 0.13968 0.16407 0.19389 -0.00757 -0.06937 -0.00955 20  VAL A CG1 
59   C CG2 . VAL A 6   ? 0.11156 0.16320 0.19048 0.00283  -0.07361 0.01273  20  VAL A CG2 
69   N N   . SER A 7   ? 0.11164 0.16167 0.19703 -0.00713 -0.07288 0.01107  21  SER A N   
70   C CA  . SER A 7   ? 0.11307 0.17858 0.23192 -0.00918 -0.07590 0.02740  21  SER A CA  
71   C C   . SER A 7   ? 0.10672 0.19837 0.23388 -0.00760 -0.07834 0.01917  21  SER A C   
72   O O   . SER A 7   ? 0.10780 0.21876 0.27039 0.00623  -0.07208 0.03166  21  SER A O   
73   C CB  . SER A 7   ? 0.12951 0.17874 0.23373 0.00709  -0.07051 0.03673  21  SER A CB  
74   O OG  . SER A 7   ? 0.13555 0.18890 0.26966 -0.01227 -0.06050 0.02890  21  SER A OG  
80   N N   . SER A 8   ? 0.12359 0.20186 0.22030 0.00496  -0.09008 0.01113  22  SER A N   
81   C CA  . SER A 8   ? 0.14621 0.21079 0.24188 0.00003  -0.10587 0.00424  22  SER A CA  
82   C C   . SER A 8   ? 0.15847 0.21442 0.26273 0.00828  -0.11357 0.01237  22  SER A C   
83   O O   . SER A 8   ? 0.18808 0.21702 0.28872 0.01255  -0.13281 0.00093  22  SER A O   
84   C CB  . SER A 8   ? 0.16607 0.23029 0.23387 0.00044  -0.11478 -0.00585 22  SER A CB  
85   O OG  . SER A 8   ? 0.18159 0.25483 0.23334 0.02648  -0.11882 -0.00087 22  SER A OG  
91   N N   . ILE A 9   ? 0.15440 0.20032 0.21896 0.00508  -0.10507 0.01947  23  ILE A N   
92   C CA  . ILE A 9   ? 0.16195 0.19952 0.21950 0.01186  -0.10877 0.01133  23  ILE A CA  
93   C C   . ILE A 9   ? 0.15044 0.20456 0.23303 0.00921  -0.10545 0.01079  23  ILE A C   
94   O O   . ILE A 9   ? 0.15918 0.21668 0.23462 -0.00154 -0.10976 0.02460  23  ILE A O   
95   C CB  . ILE A 9   ? 0.17697 0.20189 0.20449 0.01680  -0.09957 0.01038  23  ILE A CB  
96   C CG1 . ILE A 9   ? 0.17583 0.19336 0.20289 0.00194  -0.08462 0.01392  23  ILE A CG1 
97   C CG2 . ILE A 9   ? 0.19456 0.20997 0.22106 0.01363  -0.09854 0.00258  23  ILE A CG2 
98   C CD1 . ILE A 9   ? 0.19394 0.19704 0.21748 -0.01118 -0.07859 0.01427  23  ILE A CD1 
110  N N   . ASP A 10  ? 0.15039 0.20801 0.21604 0.01263  -0.09322 0.01914  24  ASP A N   
111  C CA  . ASP A 10  ? 0.14367 0.22498 0.23146 0.02809  -0.09881 -0.00263 24  ASP A CA  
112  C C   . ASP A 10  ? 0.13002 0.21151 0.21284 0.03615  -0.08687 -0.00228 24  ASP A C   
113  O O   . ASP A 10  ? 0.13466 0.23590 0.22106 0.04463  -0.08238 -0.01861 24  ASP A O   
114  C CB  . ASP A 10  ? 0.17198 0.25983 0.27596 0.03524  -0.11213 -0.00522 24  ASP A CB  
115  C CG  . ASP A 10  ? 0.21870 0.29209 0.36072 0.06280  -0.09721 0.01270  24  ASP A CG  
116  O OD1 . ASP A 10  ? 0.22492 0.30928 0.39293 0.04815  -0.09298 0.03097  24  ASP A OD1 
117  O OD2 . ASP A 10  ? 0.28851 0.30866 0.42065 0.07747  -0.03144 0.01763  24  ASP A OD2 
122  N N   . THR A 11  ? 0.13163 0.18861 0.20290 0.03044  -0.08466 -0.00426 25  THR A N   
123  C CA  . THR A 11  ? 0.14066 0.18902 0.19209 0.02789  -0.09210 -0.00021 25  THR A CA  
124  C C   . THR A 11  ? 0.12892 0.17995 0.18798 0.02022  -0.08817 -0.00654 25  THR A C   
125  O O   . THR A 11  ? 0.16276 0.18625 0.19578 0.01710  -0.07875 -0.01137 25  THR A O   
126  C CB  . THR A 11  ? 0.15073 0.19674 0.20385 0.01477  -0.08510 0.01466  25  THR A CB  
127  O OG1 . THR A 11  ? 0.15805 0.21333 0.20471 0.00596  -0.07936 0.04060  25  THR A OG1 
128  C CG2 . THR A 11  ? 0.15957 0.20617 0.21233 0.00849  -0.08049 0.01058  25  THR A CG2 
136  N N   . PHE A 12  ? 0.11209 0.17150 0.18191 0.01152  -0.07987 0.00108  26  PHE A N   
137  C CA  . PHE A 12  ? 0.11396 0.17129 0.18325 0.01906  -0.07034 -0.00194 26  PHE A CA  
138  C C   . PHE A 12  ? 0.10393 0.18076 0.19374 0.00739  -0.07159 -0.00203 26  PHE A C   
139  O O   . PHE A 12  ? 0.10241 0.19302 0.19107 0.01978  -0.07259 0.00650  26  PHE A O   
140  C CB  . PHE A 12  ? 0.11461 0.17203 0.16743 0.01027  -0.06543 0.00964  26  PHE A CB  
141  C CG  . PHE A 12  ? 0.09653 0.17311 0.17499 0.01256  -0.06832 0.01491  26  PHE A CG  
142  C CD1 . PHE A 12  ? 0.10629 0.17705 0.18471 0.01726  -0.05271 0.01525  26  PHE A CD1 
143  C CD2 . PHE A 12  ? 0.12111 0.16844 0.18113 0.01167  -0.05957 0.02166  26  PHE A CD2 
144  C CE1 . PHE A 12  ? 0.12408 0.16558 0.19914 0.01420  -0.04521 0.01210  26  PHE A CE1 
145  C CE2 . PHE A 12  ? 0.11964 0.17132 0.18233 0.01991  -0.05866 0.00843  26  PHE A CE2 
146  C CZ  . PHE A 12  ? 0.12417 0.17584 0.19201 0.01764  -0.04422 0.02217  26  PHE A CZ  
156  N N   . LEU A 13  ? 0.10636 0.19077 0.18975 -0.00118 -0.07816 0.00321  27  LEU A N   
157  C CA  . LEU A 13  ? 0.09625 0.19379 0.22479 -0.00521 -0.07113 0.00697  27  LEU A CA  
158  C C   . LEU A 13  ? 0.07916 0.18923 0.21332 0.00674  -0.05451 0.01269  27  LEU A C   
159  O O   . LEU A 13  ? 0.08228 0.20015 0.23228 0.00085  -0.04632 0.01557  27  LEU A O   
160  C CB  . LEU A 13  ? 0.11444 0.21903 0.26197 -0.01429 -0.08350 0.01775  27  LEU A CB  
161  C CG  . LEU A 13  ? 0.14465 0.24058 0.28549 -0.02686 -0.10462 0.01443  27  LEU A CG  
162  C CD1 . LEU A 13  ? 0.16259 0.25939 0.33269 -0.02234 -0.11956 0.01690  27  LEU A CD1 
163  C CD2 . LEU A 13  ? 0.16105 0.24504 0.26272 -0.03920 -0.08646 0.00357  27  LEU A CD2 
175  N N   . PRO A 14  ? 0.07673 0.17843 0.18949 0.00363  -0.05562 0.00804  28  PRO A N   
176  C CA  . PRO A 14  ? 0.08593 0.18478 0.20759 -0.00101 -0.04600 0.00347  28  PRO A CA  
177  C C   . PRO A 14  ? 0.07538 0.20783 0.20489 -0.00013 -0.03836 -0.00753 28  PRO A C   
178  O O   . PRO A 14  ? 0.09894 0.24692 0.19910 0.02527  -0.02727 0.01605  28  PRO A O   
179  C CB  . PRO A 14  ? 0.09899 0.18324 0.21028 0.00106  -0.04106 -0.00238 28  PRO A CB  
180  C CG  . PRO A 14  ? 0.08719 0.18365 0.22365 0.00750  -0.04692 0.00049  28  PRO A CG  
181  C CD  . PRO A 14  ? 0.08378 0.18046 0.21641 -0.00023 -0.04725 -0.00760 28  PRO A CD  
189  N N   . VAL A 15  ? 0.06882 0.19910 0.16975 -0.00039 -0.04599 -0.00812 29  VAL A N   
190  C CA  . VAL A 15  ? 0.06722 0.20198 0.17216 -0.00123 -0.04467 -0.00160 29  VAL A CA  
191  C C   . VAL A 15  ? 0.08089 0.20799 0.17390 -0.00464 -0.05052 0.00734  29  VAL A C   
192  O O   . VAL A 15  ? 0.08102 0.20949 0.18091 -0.00247 -0.05624 0.01395  29  VAL A O   
193  C CB  . VAL A 15  ? 0.07019 0.20815 0.17045 -0.00275 -0.04583 0.00177  29  VAL A CB  
194  C CG1 . VAL A 15  ? 0.07674 0.21609 0.17459 -0.00065 -0.04925 0.01503  29  VAL A CG1 
195  C CG2 . VAL A 15  ? 0.07536 0.23318 0.19269 -0.01018 -0.04611 -0.00424 29  VAL A CG2 
205  N N   . LEU A 16  ? 0.08533 0.19223 0.16171 -0.00122 -0.05614 0.01537  30  LEU A N   
206  C CA  . LEU A 16  ? 0.09471 0.19651 0.18088 -0.00018 -0.06034 0.02875  30  LEU A CA  
207  C C   . LEU A 16  ? 0.08853 0.20006 0.19020 -0.01262 -0.05611 0.01465  30  LEU A C   
208  O O   . LEU A 16  ? 0.11279 0.20025 0.19971 0.00034  -0.03518 0.02611  30  LEU A O   
209  C CB  . LEU A 16  ? 0.11684 0.20029 0.19358 0.00266  -0.06217 0.01653  30  LEU A CB  
210  C CG  . LEU A 16  ? 0.14690 0.20281 0.20367 -0.00172 -0.05150 0.00268  30  LEU A CG  
211  C CD1 . LEU A 16  ? 0.17750 0.21088 0.21138 -0.00704 -0.04648 0.01289  30  LEU A CD1 
212  C CD2 . LEU A 16  ? 0.13122 0.20322 0.22369 0.00028  -0.03177 -0.00310 30  LEU A CD2 
224  N N   . ASN A 17  ? 0.08655 0.20567 0.17655 -0.00208 -0.04805 0.01949  31  ASN A N   
225  C CA  . ASN A 17  ? 0.08308 0.22246 0.19356 0.00254  -0.05430 0.00824  31  ASN A CA  
226  C C   . ASN A 17  ? 0.08246 0.22450 0.18233 0.00287  -0.04581 0.00278  31  ASN A C   
227  O O   . ASN A 17  ? 0.09768 0.23501 0.18882 0.00071  -0.04133 0.00827  31  ASN A O   
228  C CB  . ASN A 17  ? 0.08315 0.23196 0.22305 0.01261  -0.05224 0.02144  31  ASN A CB  
229  C CG  . ASN A 17  ? 0.10787 0.24804 0.22722 0.00580  -0.03697 0.01629  31  ASN A CG  
230  O OD1 . ASN A 17  ? 0.09908 0.25946 0.25351 0.00435  -0.03483 0.02609  31  ASN A OD1 
231  N ND2 . ASN A 17  ? 0.12857 0.25497 0.25224 0.02716  -0.01228 0.00549  31  ASN A ND2 
238  N N   . GLU A 18  ? 0.07064 0.21289 0.19311 0.00732  -0.04677 -0.00403 32  GLU A N   
239  C CA  . GLU A 18  ? 0.07935 0.20741 0.20661 0.01204  -0.05274 -0.01818 32  GLU A CA  
240  C C   . GLU A 18  ? 0.07490 0.19588 0.17411 0.00719  -0.04878 0.00987  32  GLU A C   
241  O O   . GLU A 18  ? 0.07484 0.19591 0.18286 0.00700  -0.04557 -0.00655 32  GLU A O   
242  C CB  . GLU A 18  ? 0.12939 0.23256 0.27135 0.02935  -0.08905 -0.05024 32  GLU A CB  
243  C CG  . GLU A 18  ? 0.16968 0.26385 0.34066 0.01752  -0.06682 -0.04175 32  GLU A CG  
244  C CD  . GLU A 18  ? 0.20850 0.27315 0.37179 0.01308  -0.07996 -0.02575 32  GLU A CD  
245  O OE1 . GLU A 18  ? 0.24456 0.27236 0.37510 -0.00597 -0.06101 -0.01183 32  GLU A OE1 
246  O OE2 . GLU A 18  ? 0.22080 0.28568 0.40933 0.01326  -0.06010 -0.02053 32  GLU A OE2 
253  N N   . ALA A 19  ? 0.08148 0.19147 0.18201 -0.00314 -0.04705 0.00564  33  ALA A N   
254  C CA  . ALA A 19  ? 0.07945 0.19494 0.16807 0.00727  -0.04403 -0.00030 33  ALA A CA  
255  C C   . ALA A 19  ? 0.08134 0.20014 0.16389 -0.00374 -0.05399 0.01374  33  ALA A C   
256  O O   . ALA A 19  ? 0.09635 0.21141 0.19538 -0.00275 -0.06341 -0.00464 33  ALA A O   
257  C CB  . ALA A 19  ? 0.10033 0.19570 0.18394 0.01463  -0.03354 0.00380  33  ALA A CB  
263  N N   . LYS A 20  ? 0.09504 0.18435 0.16878 -0.00717 -0.05418 0.00794  34  LYS A N   
264  C CA  . LYS A 20  ? 0.09621 0.17247 0.18013 -0.01481 -0.04466 0.00977  34  LYS A CA  
265  C C   . LYS A 20  ? 0.10118 0.16825 0.17540 -0.00661 -0.04955 0.01566  34  LYS A C   
266  O O   . LYS A 20  ? 0.10082 0.18019 0.17184 -0.02069 -0.04937 -0.00230 34  LYS A O   
267  C CB  . LYS A 20  ? 0.10649 0.18249 0.17657 -0.01338 -0.04361 0.02349  34  LYS A CB  
268  C CG  . LYS A 20  ? 0.10891 0.20238 0.16403 -0.01109 -0.04622 0.04055  34  LYS A CG  
269  C CD  . LYS A 20  ? 0.13422 0.21916 0.17650 -0.00699 -0.04406 0.03422  34  LYS A CD  
270  C CE  . LYS A 20  ? 0.14520 0.22522 0.20027 -0.01037 -0.06330 0.03059  34  LYS A CE  
271  N NZ  . LYS A 20  ? 0.16614 0.22563 0.20393 -0.00932 -0.06490 0.04005  34  LYS A NZ  
285  N N   . LEU A 21  ? 0.09488 0.15397 0.18040 0.01040  -0.05798 0.01198  35  LEU A N   
286  C CA  . LEU A 21  ? 0.10497 0.15332 0.17426 0.00123  -0.05005 0.01203  35  LEU A CA  
287  C C   . LEU A 21  ? 0.10004 0.15047 0.17471 0.00117  -0.05913 0.01561  35  LEU A C   
288  O O   . LEU A 21  ? 0.11945 0.14870 0.19013 -0.00498 -0.05225 0.01773  35  LEU A O   
289  C CB  . LEU A 21  ? 0.10813 0.16692 0.17276 -0.00726 -0.06236 0.01580  35  LEU A CB  
290  C CG  . LEU A 21  ? 0.11627 0.16988 0.16802 -0.00448 -0.07849 0.01302  35  LEU A CG  
291  C CD1 . LEU A 21  ? 0.15237 0.18110 0.17769 -0.01067 -0.04068 0.01375  35  LEU A CD1 
292  C CD2 . LEU A 21  ? 0.12811 0.18272 0.17387 -0.00825 -0.07022 0.00558  35  LEU A CD2 
304  N N   . GLN A 22  ? 0.09926 0.15867 0.18216 0.00017  -0.06542 0.02414  36  GLN A N   
305  C CA  . GLN A 22  ? 0.10657 0.16536 0.17625 -0.00660 -0.06596 0.01995  36  GLN A CA  
306  C C   . GLN A 22  ? 0.10186 0.15135 0.17220 -0.00031 -0.07059 0.02681  36  GLN A C   
307  O O   . GLN A 22  ? 0.11125 0.14597 0.18623 -0.00367 -0.05188 0.02285  36  GLN A O   
308  C CB  . GLN A 22  ? 0.11234 0.18555 0.17133 -0.00265 -0.06818 0.00759  36  GLN A CB  
309  C CG  . GLN A 22  ? 0.12409 0.20301 0.19095 -0.00117 -0.07418 0.00985  36  GLN A CG  
310  C CD  . GLN A 22  ? 0.16474 0.21612 0.21409 -0.00344 -0.07672 0.00994  36  GLN A CD  
311  O OE1 . GLN A 22  ? 0.18123 0.22605 0.24578 -0.01328 -0.08890 0.00560  36  GLN A OE1 
312  N NE2 . GLN A 22  ? 0.19330 0.23626 0.22268 0.00064  -0.09572 0.00952  36  GLN A NE2 
321  N N   . TRP A 23  ? 0.11333 0.14584 0.17730 0.00239  -0.06229 0.02844  37  TRP A N   
322  C CA  . TRP A 23  ? 0.12361 0.14371 0.19400 -0.00181 -0.06613 0.01829  37  TRP A CA  
323  C C   . TRP A 23  ? 0.13241 0.14773 0.19196 -0.00893 -0.07431 0.01084  37  TRP A C   
324  O O   . TRP A 23  ? 0.13646 0.16000 0.22553 -0.00898 -0.05419 0.02708  37  TRP A O   
325  C CB  . TRP A 23  ? 0.13408 0.16399 0.18723 -0.00330 -0.06535 0.01442  37  TRP A CB  
326  C CG  . TRP A 23  ? 0.13420 0.16247 0.18518 0.00527  -0.08174 0.01334  37  TRP A CG  
327  C CD1 . TRP A 23  ? 0.13794 0.16137 0.18403 0.01944  -0.07525 0.01027  37  TRP A CD1 
328  C CD2 . TRP A 23  ? 0.13323 0.15367 0.19262 0.00969  -0.08011 0.00946  37  TRP A CD2 
329  N NE1 . TRP A 23  ? 0.12108 0.15614 0.19259 0.01791  -0.06412 0.00828  37  TRP A NE1 
330  C CE2 . TRP A 23  ? 0.14339 0.15842 0.19461 0.01442  -0.08613 0.00601  37  TRP A CE2 
331  C CE3 . TRP A 23  ? 0.14830 0.16777 0.20402 0.00258  -0.09115 -0.00246 37  TRP A CE3 
332  C CZ2 . TRP A 23  ? 0.16395 0.17393 0.19630 0.01728  -0.07577 -0.00042 37  TRP A CZ2 
333  C CZ3 . TRP A 23  ? 0.16367 0.16700 0.22059 0.00678  -0.09117 0.01002  37  TRP A CZ3 
334  C CH2 . TRP A 23  ? 0.16907 0.17542 0.22141 0.01072  -0.08757 0.00125  37  TRP A CH2 
345  N N   . PRO A 24  ? 0.12752 0.15235 0.20610 0.00104  -0.07095 0.01461  38  PRO A N   
346  C CA  . PRO A 24  ? 0.12707 0.15771 0.20710 0.01275  -0.07666 0.01449  38  PRO A CA  
347  C C   . PRO A 24  ? 0.13057 0.16430 0.20934 0.01104  -0.07892 0.02593  38  PRO A C   
348  O O   . PRO A 24  ? 0.13686 0.16138 0.22272 0.01031  -0.06807 0.02502  38  PRO A O   
349  C CB  . PRO A 24  ? 0.14502 0.16331 0.24270 0.01584  -0.05612 0.00466  38  PRO A CB  
350  C CG  . PRO A 24  ? 0.16983 0.16472 0.24254 0.01164  -0.05638 0.01125  38  PRO A CG  
351  C CD  . PRO A 24  ? 0.15310 0.15059 0.22172 0.00939  -0.05704 0.01466  38  PRO A CD  
359  N N   . THR A 25  ? 0.15276 0.18184 0.20491 -0.00613 -0.07852 0.02111  39  THR A N   
360  C CA  . THR A 25  ? 0.17370 0.19752 0.21123 0.00520  -0.07474 0.02323  39  THR A CA  
361  C C   . THR A 25  ? 0.15491 0.20476 0.18854 0.00403  -0.08826 0.00552  39  THR A C   
362  O O   . THR A 25  ? 0.15048 0.21578 0.21042 0.01282  -0.08557 0.01537  39  THR A O   
363  C CB  . THR A 25  ? 0.21658 0.20152 0.23674 0.01878  -0.06928 0.03243  39  THR A CB  
364  O OG1 . THR A 25  ? 0.25684 0.20509 0.24519 0.01478  -0.07165 0.05102  39  THR A OG1 
365  C CG2 . THR A 25  ? 0.23738 0.20681 0.26363 0.02974  -0.06473 0.01747  39  THR A CG2 
373  N N   . SER A 26  ? 0.16619 0.21047 0.20249 0.01622  -0.08419 0.00604  40  SER A N   
374  C CA  . SER A 26  ? 0.16439 0.21775 0.20563 0.00560  -0.08278 0.00566  40  SER A CA  
375  C C   . SER A 26  ? 0.16637 0.22048 0.22048 0.01703  -0.08000 0.01835  40  SER A C   
376  O O   . SER A 26  ? 0.16982 0.23116 0.24884 0.00937  -0.06403 0.02449  40  SER A O   
377  C CB  . SER A 26  ? 0.18029 0.24056 0.22447 -0.00814 -0.07407 -0.00237 40  SER A CB  
378  O OG  . SER A 26  ? 0.20519 0.25444 0.23630 -0.00685 -0.05264 -0.01847 40  SER A OG  
384  N N   . ALA A 27  ? 0.17260 0.22669 0.24166 0.01325  -0.08576 0.02987  41  ALA A N   
385  C CA  . ALA A 27  ? 0.17621 0.22265 0.25826 0.00928  -0.06848 0.03892  41  ALA A CA  
386  C C   . ALA A 27  ? 0.15871 0.20662 0.22093 -0.01847 -0.07675 0.03548  41  ALA A C   
387  O O   . ALA A 27  ? 0.16630 0.20489 0.22543 -0.02439 -0.07098 0.03260  41  ALA A O   
388  C CB  . ALA A 27  ? 0.19747 0.23367 0.29653 0.01066  -0.06836 0.02132  41  ALA A CB  
394  N N   . LEU A 28  ? 0.17332 0.20431 0.21192 -0.01104 -0.06460 0.05513  42  LEU A N   
395  C CA  . LEU A 28  ? 0.16715 0.19124 0.20442 -0.01035 -0.07730 0.04326  42  LEU A CA  
396  C C   . LEU A 28  ? 0.17839 0.16278 0.22523 -0.01982 -0.07512 0.02273  42  LEU A C   
397  O O   . LEU A 28  ? 0.22642 0.16483 0.24084 -0.01061 -0.05353 0.03399  42  LEU A O   
398  C CB  . LEU A 28  ? 0.17600 0.21283 0.21090 -0.02105 -0.03768 0.04087  42  LEU A CB  
399  C CG  . LEU A 28  ? 0.17246 0.23622 0.23616 -0.02337 -0.03541 0.04593  42  LEU A CG  
400  C CD1 . LEU A 28  ? 0.15099 0.24658 0.24649 -0.01225 -0.05453 0.04299  42  LEU A CD1 
401  C CD2 . LEU A 28  ? 0.20292 0.24399 0.27170 -0.03122 -0.01158 0.03983  42  LEU A CD2 
413  N N   . ALA A 29  ? 0.14711 0.15869 0.20630 -0.02268 -0.08039 0.02382  43  ALA A N   
414  C CA  . ALA A 29  ? 0.13589 0.17240 0.19559 -0.01812 -0.07553 0.01674  43  ALA A CA  
415  C C   . ALA A 29  ? 0.12707 0.17077 0.19303 -0.02763 -0.06632 0.00587  43  ALA A C   
416  O O   . ALA A 29  ? 0.13614 0.17652 0.22619 -0.01745 -0.08368 0.00389  43  ALA A O   
417  C CB  . ALA A 29  ? 0.13560 0.17299 0.19668 -0.02077 -0.06322 0.00684  43  ALA A CB  
423  N N   . ALA A 30  ? 0.12153 0.17873 0.19005 -0.02000 -0.06406 0.00895  44  ALA A N   
424  C CA  . ALA A 30  ? 0.10745 0.17672 0.19605 -0.01827 -0.06364 -0.00108 44  ALA A CA  
425  C C   . ALA A 30  ? 0.11347 0.17716 0.20873 -0.00973 -0.05036 0.01155  44  ALA A C   
426  O O   . ALA A 30  ? 0.11279 0.18294 0.19894 -0.02293 -0.05199 0.00545  44  ALA A O   
427  C CB  . ALA A 30  ? 0.11468 0.18282 0.18694 -0.01126 -0.05179 0.00860  44  ALA A CB  
433  N N   . SER A 31  ? 0.11428 0.18583 0.19796 -0.01328 -0.04974 0.01205  45  SER A N   
434  C CA  . SER A 31  ? 0.12621 0.20314 0.19188 -0.01184 -0.03653 0.02314  45  SER A CA  
435  C C   . SER A 31  ? 0.11005 0.19656 0.18629 -0.01869 -0.04734 0.01486  45  SER A C   
436  O O   . SER A 31  ? 0.11902 0.19250 0.18898 -0.01128 -0.05291 0.01688  45  SER A O   
437  C CB  . SER A 31  ? 0.12456 0.22135 0.21910 -0.02454 -0.02916 0.03688  45  SER A CB  
438  O OG  . SER A 31  ? 0.12797 0.23449 0.25897 -0.02845 -0.03733 0.02829  45  SER A OG  
444  N N   . SER A 32  ? 0.12755 0.19952 0.18533 -0.01230 -0.04854 0.02002  46  SER A N   
445  C CA  . SER A 32  ? 0.11670 0.20490 0.18415 -0.00121 -0.05003 0.02278  46  SER A CA  
446  C C   . SER A 32  ? 0.10098 0.21230 0.21158 0.00260  -0.04210 0.02830  46  SER A C   
447  O O   . SER A 32  ? 0.10841 0.21218 0.21110 -0.00233 -0.05449 0.01956  46  SER A O   
448  C CB  . SER A 32  ? 0.13223 0.20295 0.20443 -0.00469 -0.04606 0.00843  46  SER A CB  
449  O OG  . SER A 32  ? 0.14147 0.20625 0.21076 0.00861  -0.01917 0.01339  46  SER A OG  
455  N N   . GLU A 33  ? 0.11361 0.22996 0.22763 -0.01522 -0.04702 0.03492  47  GLU A N   
456  C CA  A GLU A 33  ? 0.14264 0.24391 0.25690 -0.02867 -0.02007 0.01721  47  GLU A CA  
457  C CA  B GLU A 33  ? 0.11937 0.24612 0.26528 -0.03273 -0.04092 0.02787  47  GLU A CA  
458  C C   . GLU A 33  ? 0.12102 0.23122 0.24606 -0.02859 -0.05451 0.02446  47  GLU A C   
459  O O   . GLU A 33  ? 0.12462 0.22635 0.25931 -0.01849 -0.06618 0.02355  47  GLU A O   
460  C CB  A GLU A 33  ? 0.21443 0.26592 0.29237 -0.04565 0.02819  -0.00457 47  GLU A CB  
461  C CB  B GLU A 33  ? 0.15090 0.27130 0.31641 -0.05983 -0.03029 0.02724  47  GLU A CB  
462  C CG  A GLU A 33  ? 0.29278 0.28619 0.33929 -0.04962 0.05932  -0.02869 47  GLU A CG  
463  C CG  B GLU A 33  ? 0.19585 0.29341 0.38257 -0.06901 -0.02215 0.02833  47  GLU A CG  
464  C CD  A GLU A 33  ? 0.35639 0.30278 0.37739 -0.05236 0.09068  -0.04132 47  GLU A CD  
465  C CD  B GLU A 33  ? 0.25391 0.31295 0.44643 -0.07475 0.00477  0.02818  47  GLU A CD  
466  O OE1 A GLU A 33  ? 0.38534 0.30671 0.39413 -0.06094 0.10529  -0.04522 47  GLU A OE1 
467  O OE1 B GLU A 33  ? 0.27820 0.32069 0.46798 -0.08176 0.02114  0.02352  47  GLU A OE1 
468  O OE2 A GLU A 33  ? 0.37614 0.31580 0.38149 -0.05014 0.09795  -0.03840 47  GLU A OE2 
469  O OE2 B GLU A 33  ? 0.28540 0.32283 0.48506 -0.07108 0.01943  0.02976  47  GLU A OE2 
480  N N   . GLU A 34  ? 0.11190 0.21380 0.23055 -0.03206 -0.05108 0.03243  48  GLU A N   
481  C CA  . GLU A 34  ? 0.12124 0.19569 0.22981 -0.02624 -0.06650 0.01909  48  GLU A CA  
482  C C   . GLU A 34  ? 0.11277 0.18421 0.20863 -0.01802 -0.06959 0.01606  48  GLU A C   
483  O O   . GLU A 34  ? 0.11582 0.18797 0.21699 -0.02310 -0.06977 0.01684  48  GLU A O   
484  C CB  . GLU A 34  ? 0.14911 0.19569 0.22994 -0.03062 -0.06130 0.02143  48  GLU A CB  
485  C CG  . GLU A 34  ? 0.18492 0.20471 0.28093 -0.04236 -0.07338 0.03573  48  GLU A CG  
486  C CD  . GLU A 34  ? 0.21859 0.21960 0.35440 -0.04939 -0.08516 0.05149  48  GLU A CD  
487  O OE1 . GLU A 34  ? 0.20112 0.21142 0.36476 -0.04160 -0.08768 0.05877  48  GLU A OE1 
488  O OE2 . GLU A 34  ? 0.27440 0.24358 0.42138 -0.05166 -0.07280 0.05150  48  GLU A OE2 
495  N N   . LEU A 35  ? 0.09342 0.17716 0.21178 -0.02309 -0.06130 0.02421  49  LEU A N   
496  C CA  . LEU A 35  ? 0.08449 0.18091 0.19672 -0.01242 -0.05931 0.02272  49  LEU A CA  
497  C C   . LEU A 35  ? 0.09263 0.19104 0.20414 -0.00863 -0.05904 0.01674  49  LEU A C   
498  O O   . LEU A 35  ? 0.10644 0.20679 0.20262 0.00454  -0.07290 0.01259  49  LEU A O   
499  C CB  . LEU A 35  ? 0.08990 0.18465 0.19271 -0.01365 -0.05984 0.01760  49  LEU A CB  
500  C CG  . LEU A 35  ? 0.09600 0.19425 0.18755 -0.01528 -0.06008 0.01085  49  LEU A CG  
501  C CD1 . LEU A 35  ? 0.09850 0.21149 0.19910 -0.01840 -0.06972 0.00892  49  LEU A CD1 
502  C CD2 . LEU A 35  ? 0.11302 0.19097 0.19466 0.00350  -0.05140 0.00895  49  LEU A CD2 
514  N N   . LEU A 36  ? 0.09342 0.19771 0.20261 -0.00196 -0.06643 0.00316  50  LEU A N   
515  C CA  . LEU A 36  ? 0.09245 0.20447 0.22656 0.00501  -0.06765 0.00466  50  LEU A CA  
516  C C   . LEU A 36  ? 0.10207 0.21359 0.24904 0.00901  -0.07443 0.00414  50  LEU A C   
517  O O   . LEU A 36  ? 0.13589 0.22270 0.25821 0.00942  -0.08969 -0.01099 50  LEU A O   
518  C CB  . LEU A 36  ? 0.09753 0.20480 0.24426 -0.00005 -0.06531 -0.00549 50  LEU A CB  
519  C CG  . LEU A 36  ? 0.09866 0.20218 0.24942 0.01192  -0.06866 0.00340  50  LEU A CG  
520  C CD1 . LEU A 36  ? 0.11994 0.21862 0.27070 0.01362  -0.04441 -0.00302 50  LEU A CD1 
521  C CD2 . LEU A 36  ? 0.11388 0.20657 0.25300 0.00544  -0.06851 0.00349  50  LEU A CD2 
533  N N   . GLY A 37  ? 0.10185 0.21070 0.25479 0.00013  -0.07414 0.00965  51  GLY A N   
534  C CA  . GLY A 37  ? 0.11682 0.21844 0.26859 -0.01846 -0.07862 -0.00371 51  GLY A CA  
535  C C   . GLY A 37  ? 0.12333 0.20730 0.27973 -0.01483 -0.08028 -0.00241 51  GLY A C   
536  O O   . GLY A 37  ? 0.15738 0.22880 0.31117 -0.03629 -0.06478 -0.02263 51  GLY A O   
540  N N   . GLY A 38  ? 0.10759 0.18661 0.27570 -0.00876 -0.07706 -0.00548 52  GLY A N   
541  C CA  . GLY A 38  ? 0.11800 0.18213 0.26116 -0.01156 -0.05784 0.01298  52  GLY A CA  
542  C C   . GLY A 38  ? 0.11586 0.17297 0.21894 -0.01602 -0.07552 0.00830  52  GLY A C   
543  O O   . GLY A 38  ? 0.12832 0.18041 0.21418 -0.01413 -0.07880 0.00788  52  GLY A O   
547  N N   . TYR A 39  ? 0.10783 0.16460 0.21232 -0.01553 -0.05577 0.00826  53  TYR A N   
548  C CA  . TYR A 39  ? 0.11334 0.15446 0.19627 -0.01495 -0.06366 0.00760  53  TYR A CA  
549  C C   . TYR A 39  ? 0.11279 0.13800 0.18858 -0.01027 -0.06093 0.00907  53  TYR A C   
550  O O   . TYR A 39  ? 0.10788 0.13205 0.21685 -0.01189 -0.05460 0.01384  53  TYR A O   
551  C CB  . TYR A 39  ? 0.11300 0.17886 0.21395 -0.00386 -0.06263 0.00333  53  TYR A CB  
552  C CG  . TYR A 39  ? 0.12457 0.18236 0.19495 -0.00672 -0.06629 -0.00019 53  TYR A CG  
553  C CD1 . TYR A 39  ? 0.12987 0.18126 0.20235 -0.01508 -0.06327 -0.00300 53  TYR A CD1 
554  C CD2 . TYR A 39  ? 0.12573 0.18025 0.20433 -0.01473 -0.06053 0.01822  53  TYR A CD2 
555  C CE1 . TYR A 39  ? 0.12409 0.18617 0.19845 -0.01760 -0.07253 0.01142  53  TYR A CE1 
556  C CE2 . TYR A 39  ? 0.11713 0.17535 0.21301 -0.01693 -0.06493 -0.00104 53  TYR A CE2 
557  C CZ  . TYR A 39  ? 0.10680 0.18623 0.20385 -0.00839 -0.06762 0.00201  53  TYR A CZ  
558  O OH  . TYR A 39  ? 0.12321 0.19756 0.19939 -0.00361 -0.05909 0.00781  53  TYR A OH  
568  N N   . VAL A 40  ? 0.11791 0.13751 0.18079 -0.01295 -0.06755 0.00897  54  VAL A N   
569  C CA  . VAL A 40  ? 0.12424 0.13836 0.18554 -0.00862 -0.06837 0.00729  54  VAL A CA  
570  C C   . VAL A 40  ? 0.12338 0.13021 0.18949 -0.00691 -0.08086 0.01587  54  VAL A C   
571  O O   . VAL A 40  ? 0.14485 0.12693 0.20176 -0.01448 -0.06650 0.01640  54  VAL A O   
572  C CB  . VAL A 40  ? 0.13936 0.15967 0.18298 -0.00458 -0.09385 0.00732  54  VAL A CB  
573  C CG1 . VAL A 40  ? 0.15673 0.17138 0.21259 -0.01937 -0.10569 0.01136  54  VAL A CG1 
574  C CG2 . VAL A 40  ? 0.15030 0.16143 0.18121 0.00283  -0.06115 0.00329  54  VAL A CG2 
584  N N   . GLY A 41  ? 0.11253 0.12890 0.19131 -0.01663 -0.07488 0.00490  55  GLY A N   
585  C CA  . GLY A 41  ? 0.12613 0.13916 0.20163 -0.00907 -0.06658 0.00090  55  GLY A CA  
586  C C   . GLY A 41  ? 0.12062 0.14255 0.18491 -0.00828 -0.08299 0.00393  55  GLY A C   
587  O O   . GLY A 41  ? 0.12415 0.13880 0.18284 -0.00630 -0.07310 0.00228  55  GLY A O   
591  N N   . SER A 42  ? 0.13739 0.14061 0.18200 -0.00389 -0.05974 0.00852  56  SER A N   
592  C CA  A SER A 42  ? 0.14370 0.15500 0.19027 -0.00999 -0.04779 -0.00211 56  SER A CA  
593  C CA  B SER A 42  ? 0.14297 0.14910 0.19003 -0.00936 -0.05351 -0.00035 56  SER A CA  
594  C C   . SER A 42  ? 0.12616 0.14490 0.18320 -0.00527 -0.05604 0.01682  56  SER A C   
595  O O   . SER A 42  ? 0.12931 0.15356 0.18351 -0.00822 -0.05848 0.00570  56  SER A O   
596  C CB  A SER A 42  ? 0.15936 0.17397 0.23495 -0.00493 -0.03675 -0.01213 56  SER A CB  
597  C CB  B SER A 42  ? 0.16337 0.15975 0.21432 -0.01455 -0.04961 -0.02142 56  SER A CB  
598  O OG  A SER A 42  ? 0.16502 0.17964 0.25725 -0.00774 -0.02807 -0.01067 56  SER A OG  
599  O OG  B SER A 42  ? 0.17930 0.16545 0.23007 -0.02271 -0.05083 -0.03870 56  SER A OG  
608  N N   . GLN A 43  ? 0.11324 0.14197 0.18240 -0.00772 -0.06306 0.00884  57  GLN A N   
609  C CA  . GLN A 43  ? 0.10862 0.15118 0.17857 -0.01357 -0.06704 0.01067  57  GLN A CA  
610  C C   . GLN A 43  ? 0.10539 0.14440 0.17820 -0.01716 -0.05731 0.00767  57  GLN A C   
611  O O   . GLN A 43  ? 0.11466 0.14482 0.17690 -0.00435 -0.07295 0.00841  57  GLN A O   
612  C CB  . GLN A 43  ? 0.11690 0.14920 0.18977 -0.01258 -0.06705 0.01599  57  GLN A CB  
613  C CG  . GLN A 43  ? 0.11294 0.15060 0.18506 0.00226  -0.07378 0.01684  57  GLN A CG  
614  C CD  . GLN A 43  ? 0.12461 0.14203 0.17789 -0.00113 -0.05937 0.01581  57  GLN A CD  
615  O OE1 . GLN A 43  ? 0.15143 0.14577 0.19421 -0.01526 -0.04892 0.00465  57  GLN A OE1 
616  N NE2 . GLN A 43  ? 0.12763 0.15086 0.19274 -0.01187 -0.06155 0.00395  57  GLN A NE2 
625  N N   . PHE A 44  ? 0.11122 0.14130 0.16865 0.00132  -0.06000 0.00368  58  PHE A N   
626  C CA  . PHE A 44  ? 0.10110 0.14039 0.16967 -0.00350 -0.06926 0.00620  58  PHE A CA  
627  C C   . PHE A 44  ? 0.10290 0.13544 0.17339 -0.01281 -0.06004 0.00561  58  PHE A C   
628  O O   . PHE A 44  ? 0.09997 0.13782 0.17413 -0.00490 -0.06621 0.01505  58  PHE A O   
629  C CB  . PHE A 44  ? 0.10765 0.14091 0.17274 -0.00803 -0.06819 0.02102  58  PHE A CB  
630  C CG  . PHE A 44  ? 0.12047 0.14096 0.16056 -0.00472 -0.06223 0.01693  58  PHE A CG  
631  C CD1 . PHE A 44  ? 0.12747 0.14731 0.15713 -0.00987 -0.05978 0.00578  58  PHE A CD1 
632  C CD2 . PHE A 44  ? 0.11320 0.14759 0.17307 -0.00405 -0.05817 0.01290  58  PHE A CD2 
633  C CE1 . PHE A 44  ? 0.12971 0.15705 0.17036 -0.00049 -0.06712 0.01415  58  PHE A CE1 
634  C CE2 . PHE A 44  ? 0.10480 0.16445 0.18320 -0.00309 -0.07067 0.01718  58  PHE A CE2 
635  C CZ  . PHE A 44  ? 0.13009 0.16236 0.16755 0.00913  -0.06886 0.01352  58  PHE A CZ  
645  N N   . TYR A 45  ? 0.10284 0.14151 0.15909 -0.01122 -0.06085 0.01441  59  TYR A N   
646  C CA  . TYR A 45  ? 0.11375 0.14776 0.15122 -0.01347 -0.07536 -0.00501 59  TYR A CA  
647  C C   . TYR A 45  ? 0.11167 0.15031 0.15711 -0.02106 -0.07378 -0.00292 59  TYR A C   
648  O O   . TYR A 45  ? 0.11289 0.15476 0.15944 -0.01098 -0.07745 0.00707  59  TYR A O   
649  C CB  . TYR A 45  ? 0.13218 0.15099 0.18219 -0.00238 -0.07652 0.00550  59  TYR A CB  
650  C CG  . TYR A 45  ? 0.14746 0.15687 0.17032 -0.00036 -0.05713 0.00101  59  TYR A CG  
651  C CD1 . TYR A 45  ? 0.18939 0.17653 0.16986 0.00670  -0.04349 0.01079  59  TYR A CD1 
652  C CD2 . TYR A 45  ? 0.14778 0.18365 0.18665 0.00769  -0.05552 0.01222  59  TYR A CD2 
653  C CE1 . TYR A 45  ? 0.19527 0.19307 0.19050 0.00169  -0.03296 0.01457  59  TYR A CE1 
654  C CE2 . TYR A 45  ? 0.15872 0.19610 0.19897 0.00843  -0.04315 0.00853  59  TYR A CE2 
655  C CZ  . TYR A 45  ? 0.17670 0.21112 0.19200 -0.00703 -0.04989 -0.00671 59  TYR A CZ  
656  O OH  . TYR A 45  ? 0.20734 0.24093 0.21760 0.00384  -0.03118 -0.00203 59  TYR A OH  
666  N N   . LEU A 46  ? 0.11677 0.13790 0.17884 -0.01929 -0.07908 0.00510  60  LEU A N   
667  C CA  . LEU A 46  ? 0.11883 0.14396 0.18335 -0.02217 -0.07837 0.00483  60  LEU A CA  
668  C C   . LEU A 46  ? 0.12306 0.16614 0.16798 -0.00532 -0.08398 0.00587  60  LEU A C   
669  O O   . LEU A 46  ? 0.15655 0.17261 0.17819 -0.01392 -0.08101 -0.00725 60  LEU A O   
670  C CB  . LEU A 46  ? 0.12103 0.14563 0.18702 -0.01807 -0.07237 0.00935  60  LEU A CB  
671  C CG  . LEU A 46  ? 0.13100 0.16110 0.19068 -0.00731 -0.07279 0.01027  60  LEU A CG  
672  C CD1 . LEU A 46  ? 0.13650 0.16847 0.21879 0.00647  -0.06816 0.00350  60  LEU A CD1 
673  C CD2 . LEU A 46  ? 0.13054 0.17320 0.22781 0.00385  -0.07898 0.01676  60  LEU A CD2 
685  N N   . GLN A 47  ? 0.12949 0.17545 0.15460 0.00131  -0.07345 -0.00536 61  GLN A N   
686  C CA  . GLN A 47  ? 0.13640 0.18972 0.15500 0.00782  -0.07718 0.00369  61  GLN A CA  
687  C C   . GLN A 47  ? 0.13743 0.20575 0.16288 -0.01185 -0.07915 0.00433  61  GLN A C   
688  O O   . GLN A 47  ? 0.12317 0.20090 0.16863 -0.00470 -0.08048 0.01537  61  GLN A O   
689  C CB  . GLN A 47  ? 0.14024 0.19244 0.18090 0.00881  -0.05877 0.00728  61  GLN A CB  
690  C CG  . GLN A 47  ? 0.14070 0.20999 0.20630 0.00495  -0.05155 -0.00422 61  GLN A CG  
691  C CD  . GLN A 47  ? 0.14626 0.22238 0.18406 0.00371  -0.06840 0.00320  61  GLN A CD  
692  O OE1 . GLN A 47  ? 0.15432 0.22009 0.19303 -0.00493 -0.06346 -0.00109 61  GLN A OE1 
693  N NE2 . GLN A 47  ? 0.19977 0.23204 0.19060 -0.00283 -0.02421 -0.01190 61  GLN A NE2 
702  N N   . ASP A 48  ? 0.16485 0.23065 0.15696 -0.03493 -0.07809 0.01100  62  ASP A N   
703  C CA  . ASP A 48  ? 0.17354 0.25252 0.18345 -0.04210 -0.09813 0.03162  62  ASP A CA  
704  C C   . ASP A 48  ? 0.18345 0.23365 0.17550 -0.02972 -0.08251 0.02236  62  ASP A C   
705  O O   . ASP A 48  ? 0.22246 0.22507 0.20741 -0.03745 -0.05646 0.01894  62  ASP A O   
706  C CB  . ASP A 48  ? 0.20222 0.30463 0.22562 -0.05895 -0.10701 0.04960  62  ASP A CB  
707  C CG  . ASP A 48  ? 0.27615 0.35078 0.28928 -0.06962 -0.06717 0.05715  62  ASP A CG  
708  O OD1 . ASP A 48  ? 0.27525 0.37097 0.25302 -0.04097 -0.10436 0.10129  62  ASP A OD1 
709  O OD2 . ASP A 48  ? 0.36039 0.37030 0.38065 -0.07747 0.01213  0.05846  62  ASP A OD2 
714  N N   . GLY A 49  ? 0.14827 0.22932 0.20736 -0.01182 -0.09970 0.02533  63  GLY A N   
715  C CA  . GLY A 49  ? 0.14982 0.22497 0.21496 -0.00302 -0.09549 0.02833  63  GLY A CA  
716  C C   . GLY A 49  ? 0.14696 0.22546 0.21000 0.01613  -0.09483 0.03411  63  GLY A C   
717  O O   . GLY A 49  ? 0.15467 0.25609 0.23675 0.01248  -0.10853 0.01056  63  GLY A O   
721  N N   . LYS A 50  ? 0.13839 0.20027 0.19438 0.01198  -0.09214 0.02145  64  LYS A N   
722  C CA  . LYS A 50  ? 0.17594 0.20295 0.19218 0.00043  -0.10280 0.02496  64  LYS A CA  
723  C C   . LYS A 50  ? 0.14901 0.19279 0.16700 0.00707  -0.08885 0.03060  64  LYS A C   
724  O O   . LYS A 50  ? 0.17352 0.21284 0.16637 0.02510  -0.08533 -0.00320 64  LYS A O   
725  C CB  . LYS A 50  ? 0.23460 0.22511 0.22241 -0.01543 -0.11105 0.02117  64  LYS A CB  
726  C CG  . LYS A 50  ? 0.27362 0.25622 0.24106 -0.02861 -0.11334 0.03911  64  LYS A CG  
727  C CD  . LYS A 50  ? 0.33378 0.28938 0.33267 -0.02284 -0.07133 0.06669  64  LYS A CD  
728  C CE  . LYS A 50  ? 0.37853 0.31201 0.39763 -0.01915 -0.03064 0.09420  64  LYS A CE  
729  N NZ  . LYS A 50  ? 0.40689 0.32891 0.44411 -0.01648 -0.00636 0.10418  64  LYS A NZ  
743  N N   . TYR A 51  ? 0.11403 0.16898 0.16282 -0.00726 -0.07787 0.01690  65  TYR A N   
744  C CA  . TYR A 51  ? 0.11277 0.16292 0.16192 -0.01276 -0.07733 0.01215  65  TYR A CA  
745  C C   . TYR A 51  ? 0.11355 0.15788 0.15862 -0.01428 -0.07714 0.00408  65  TYR A C   
746  O O   . TYR A 51  ? 0.15086 0.16608 0.14879 -0.00964 -0.06300 -0.00479 65  TYR A O   
747  C CB  . TYR A 51  ? 0.11900 0.16735 0.18677 -0.00621 -0.07532 0.01328  65  TYR A CB  
748  C CG  . TYR A 51  ? 0.14293 0.16836 0.20039 -0.02066 -0.05494 0.01338  65  TYR A CG  
749  C CD1 . TYR A 51  ? 0.14979 0.17201 0.22305 -0.02217 -0.03565 -0.00047 65  TYR A CD1 
750  C CD2 . TYR A 51  ? 0.16019 0.17829 0.20355 -0.02118 -0.06383 0.01927  65  TYR A CD2 
751  C CE1 . TYR A 51  ? 0.19897 0.18322 0.20956 -0.03112 -0.02563 -0.00451 65  TYR A CE1 
752  C CE2 . TYR A 51  ? 0.19343 0.18499 0.20678 -0.02307 -0.05111 0.02162  65  TYR A CE2 
753  C CZ  . TYR A 51  ? 0.21534 0.18936 0.20357 -0.03377 -0.02468 0.01826  65  TYR A CZ  
754  O OH  . TYR A 51  ? 0.25739 0.20686 0.25386 -0.03327 0.01655  0.03094  65  TYR A OH  
764  N N   . MET A 52  ? 0.10207 0.14307 0.15273 -0.00632 -0.07161 0.00689  66  MET A N   
765  C CA  . MET A 52  ? 0.09846 0.14395 0.15217 -0.00947 -0.06942 0.00731  66  MET A CA  
766  C C   . MET A 52  ? 0.08627 0.15470 0.15929 -0.00465 -0.06293 0.01165  66  MET A C   
767  O O   . MET A 52  ? 0.09061 0.15591 0.18648 -0.00235 -0.06744 0.00739  66  MET A O   
768  C CB  . MET A 52  ? 0.08825 0.15078 0.16255 -0.00425 -0.06239 0.00621  66  MET A CB  
769  C CG  . MET A 52  ? 0.10987 0.15496 0.16431 -0.00491 -0.07710 0.00837  66  MET A CG  
770  S SD  . MET A 52  ? 0.11324 0.17195 0.16770 -0.00760 -0.06259 0.00660  66  MET A SD  
771  C CE  . MET A 52  ? 0.09971 0.17856 0.15787 -0.00864 -0.05701 0.01211  66  MET A CE  
781  N N   . GLN A 53  ? 0.09313 0.15650 0.16233 -0.00238 -0.06738 0.00604  67  GLN A N   
782  C CA  . GLN A 53  ? 0.10429 0.15323 0.15205 -0.00044 -0.05985 0.00875  67  GLN A CA  
783  C C   . GLN A 53  ? 0.08918 0.14185 0.17428 0.00196  -0.06369 0.00999  67  GLN A C   
784  O O   . GLN A 53  ? 0.10680 0.14690 0.16565 -0.00568 -0.06690 0.00856  67  GLN A O   
785  C CB  . GLN A 53  ? 0.10700 0.16201 0.16087 -0.00372 -0.05401 0.01907  67  GLN A CB  
786  C CG  . GLN A 53  ? 0.11373 0.17450 0.16468 0.00306  -0.05242 0.00992  67  GLN A CG  
787  C CD  . GLN A 53  ? 0.12168 0.18148 0.17023 0.00425  -0.04397 -0.00388 67  GLN A CD  
788  O OE1 . GLN A 53  ? 0.14609 0.20812 0.17717 0.00535  -0.03655 0.01184  67  GLN A OE1 
789  N NE2 . GLN A 53  ? 0.15767 0.18095 0.20472 -0.00634 -0.03366 -0.03443 67  GLN A NE2 
798  N N   . PHE A 54  ? 0.09466 0.13777 0.15076 -0.00501 -0.05178 0.00375  68  PHE A N   
799  C CA  . PHE A 54  ? 0.10757 0.14839 0.15458 -0.00869 -0.05347 0.01921  68  PHE A CA  
800  C C   . PHE A 54  ? 0.10619 0.15509 0.17207 0.00457  -0.04922 0.01817  68  PHE A C   
801  O O   . PHE A 54  ? 0.10160 0.15880 0.18345 0.00819  -0.04302 0.01798  68  PHE A O   
802  C CB  . PHE A 54  ? 0.10765 0.15051 0.15619 -0.00316 -0.06759 0.01307  68  PHE A CB  
803  C CG  . PHE A 54  ? 0.09183 0.14583 0.14261 -0.00071 -0.06120 0.00846  68  PHE A CG  
804  C CD1 . PHE A 54  ? 0.10002 0.13993 0.14886 -0.00575 -0.05658 0.00751  68  PHE A CD1 
805  C CD2 . PHE A 54  ? 0.09355 0.15671 0.15934 -0.00545 -0.06694 0.01507  68  PHE A CD2 
806  C CE1 . PHE A 54  ? 0.09054 0.14592 0.16171 -0.00277 -0.06374 0.01715  68  PHE A CE1 
807  C CE2 . PHE A 54  ? 0.10208 0.15161 0.16045 -0.00769 -0.05372 0.01167  68  PHE A CE2 
808  C CZ  . PHE A 54  ? 0.09170 0.14715 0.16396 -0.01172 -0.06513 -0.00408 68  PHE A CZ  
818  N N   . GLN A 55  ? 0.10600 0.14873 0.17809 0.00463  -0.05685 0.01583  69  GLN A N   
819  C CA  . GLN A 55  ? 0.12186 0.15997 0.17398 0.01661  -0.05921 0.00317  69  GLN A CA  
820  C C   . GLN A 55  ? 0.11728 0.14842 0.19132 0.01047  -0.06204 0.00036  69  GLN A C   
821  O O   . GLN A 55  ? 0.12219 0.15442 0.22081 0.00639  -0.05967 0.02187  69  GLN A O   
822  C CB  . GLN A 55  ? 0.15496 0.19681 0.21161 0.03507  -0.04503 0.00937  69  GLN A CB  
823  C CG  . GLN A 55  ? 0.17879 0.21706 0.21079 0.00908  -0.05690 -0.00357 69  GLN A CG  
824  C CD  . GLN A 55  ? 0.18985 0.23893 0.19980 -0.01336 -0.04901 -0.03079 69  GLN A CD  
825  O OE1 . GLN A 55  ? 0.19466 0.25667 0.24358 -0.01538 -0.02928 -0.03317 69  GLN A OE1 
826  N NE2 . GLN A 55  ? 0.19610 0.25240 0.19577 -0.01223 -0.03493 -0.03784 69  GLN A NE2 
835  N N   . ILE A 56  ? 0.11433 0.15317 0.19770 0.01513  -0.06387 0.00479  70  ILE A N   
836  C CA  . ILE A 56  ? 0.11754 0.15801 0.20466 0.01613  -0.06315 -0.00165 70  ILE A CA  
837  C C   . ILE A 56  ? 0.13861 0.15889 0.19930 0.02405  -0.05657 0.00959  70  ILE A C   
838  O O   . ILE A 56  ? 0.13349 0.17045 0.21791 0.03481  -0.03693 0.00493  70  ILE A O   
839  C CB  . ILE A 56  ? 0.12177 0.16470 0.20138 0.02346  -0.05746 -0.00040 70  ILE A CB  
840  C CG1 . ILE A 56  ? 0.14296 0.17855 0.20274 0.01624  -0.05968 0.01571  70  ILE A CG1 
841  C CG2 . ILE A 56  ? 0.14338 0.17518 0.19475 0.02188  -0.05304 -0.00521 70  ILE A CG2 
842  C CD1 . ILE A 56  ? 0.16844 0.18397 0.21346 0.00397  -0.05662 0.02370  70  ILE A CD1 
854  N N   . ALA A 57  ? 0.13152 0.15302 0.22280 0.02243  -0.06682 0.00260  71  ALA A N   
855  C CA  . ALA A 57  ? 0.13873 0.17222 0.24529 0.03453  -0.06516 -0.00351 71  ALA A CA  
856  C C   . ALA A 57  ? 0.14754 0.17375 0.24963 0.04142  -0.07129 0.00486  71  ALA A C   
857  O O   . ALA A 57  ? 0.16154 0.17814 0.25178 0.03096  -0.04796 0.00657  71  ALA A O   
858  C CB  . ALA A 57  ? 0.15551 0.17579 0.25148 0.03927  -0.05682 -0.01056 71  ALA A CB  
864  N N   . GLY A 58  ? 0.14305 0.19175 0.26159 0.04637  -0.08060 0.00510  72  GLY A N   
865  C CA  . GLY A 58  ? 0.16196 0.19715 0.25844 0.04867  -0.06824 0.00725  72  GLY A CA  
866  C C   . GLY A 58  ? 0.14279 0.20496 0.25718 0.03582  -0.07386 0.00787  72  GLY A C   
867  O O   . GLY A 58  ? 0.13932 0.20700 0.25953 0.04325  -0.06311 0.01386  72  GLY A O   
871  N N   . SER A 59  ? 0.14327 0.21774 0.25580 0.04309  -0.08464 0.01415  73  SER A N   
872  C CA  . SER A 59  ? 0.13976 0.22876 0.28179 0.04756  -0.08121 0.01718  73  SER A CA  
873  C C   . SER A 59  ? 0.13720 0.21674 0.27552 0.04171  -0.08297 0.02870  73  SER A C   
874  O O   . SER A 59  ? 0.15255 0.21752 0.28349 0.04377  -0.08891 0.02923  73  SER A O   
875  C CB  . SER A 59  ? 0.16078 0.24646 0.31101 0.06031  -0.07113 0.02353  73  SER A CB  
876  O OG  . SER A 59  ? 0.18543 0.26687 0.33072 0.04995  -0.07750 0.01998  73  SER A OG  
882  N N   . SER A 60  ? 0.12684 0.21195 0.25893 0.03504  -0.08300 0.01991  74  SER A N   
883  C CA  . SER A 60  ? 0.14803 0.22099 0.23630 0.02523  -0.08987 0.01997  74  SER A CA  
884  C C   . SER A 60  ? 0.14100 0.19958 0.24066 0.02222  -0.08487 0.01878  74  SER A C   
885  O O   . SER A 60  ? 0.14812 0.21764 0.25543 0.01396  -0.08299 0.01534  74  SER A O   
886  C CB  . SER A 60  ? 0.15885 0.25812 0.25561 0.00658  -0.10627 0.00748  74  SER A CB  
887  O OG  . SER A 60  ? 0.17310 0.28808 0.31282 0.01314  -0.09775 0.01973  74  SER A OG  
893  N N   . ASN A 61  ? 0.12737 0.17016 0.22617 0.03095  -0.08126 0.01753  75  ASN A N   
894  C CA  A ASN A 61  ? 0.12679 0.15808 0.21810 0.01992  -0.08050 0.01522  75  ASN A CA  
895  C CA  B ASN A 61  ? 0.13965 0.15074 0.21808 0.02274  -0.07996 0.01806  75  ASN A CA  
896  C C   . ASN A 61  ? 0.12688 0.14648 0.20832 0.00938  -0.08226 0.01407  75  ASN A C   
897  O O   . ASN A 61  ? 0.11555 0.15293 0.22345 0.01573  -0.07722 0.02766  75  ASN A O   
898  C CB  A ASN A 61  ? 0.12760 0.15827 0.22056 0.01953  -0.07869 0.01434  75  ASN A CB  
899  C CB  B ASN A 61  ? 0.17668 0.15969 0.23014 0.04375  -0.07948 0.01474  75  ASN A CB  
900  C CG  A ASN A 61  ? 0.12800 0.15862 0.22251 0.01926  -0.07760 0.01364  75  ASN A CG  
901  C CG  B ASN A 61  ? 0.23150 0.17599 0.25350 0.04759  -0.03977 0.02171  75  ASN A CG  
902  O OD1 A ASN A 61  ? 0.12806 0.15876 0.22310 0.01917  -0.07717 0.01342  75  ASN A OD1 
903  O OD1 B ASN A 61  ? 0.25759 0.19322 0.29463 0.03309  -0.03059 0.03650  75  ASN A OD1 
904  N ND2 A ASN A 61  ? 0.12806 0.15876 0.22310 0.01917  -0.07717 0.01342  75  ASN A ND2 
905  N ND2 B ASN A 61  ? 0.29884 0.19012 0.30334 0.05460  0.01203  0.02448  75  ASN A ND2 
916  N N   . ARG A 62  ? 0.11512 0.14547 0.18343 0.01592  -0.07506 0.01467  76  ARG A N   
917  C CA  . ARG A 62  ? 0.10231 0.15419 0.17640 0.01277  -0.06053 0.01335  76  ARG A CA  
918  C C   . ARG A 62  ? 0.11321 0.14824 0.16409 0.00646  -0.05174 0.02687  76  ARG A C   
919  O O   . ARG A 62  ? 0.11594 0.14784 0.19165 0.00617  -0.05957 0.02204  76  ARG A O   
920  C CB  . ARG A 62  ? 0.11247 0.16116 0.18291 0.00525  -0.06042 0.00067  76  ARG A CB  
921  C CG  . ARG A 62  ? 0.11739 0.18542 0.17842 0.01134  -0.06309 0.00521  76  ARG A CG  
922  C CD  . ARG A 62  ? 0.12658 0.20084 0.20460 0.00545  -0.04452 0.00279  76  ARG A CD  
923  N NE  . ARG A 62  ? 0.13434 0.20178 0.20057 0.00436  -0.06331 0.00414  76  ARG A NE  
924  C CZ  . ARG A 62  ? 0.14054 0.20979 0.20779 -0.00835 -0.06893 0.00709  76  ARG A CZ  
925  N NH1 . ARG A 62  ? 0.14291 0.20990 0.21620 -0.00832 -0.06758 -0.00625 76  ARG A NH1 
926  N NH2 . ARG A 62  ? 0.14555 0.21853 0.21391 0.00111  -0.09163 0.01979  76  ARG A NH2 
940  N N   . CYS A 63  ? 0.10992 0.14543 0.16945 -0.00427 -0.06098 0.02611  77  CYS A N   
941  C CA  . CYS A 63  ? 0.09045 0.15205 0.16935 0.00321  -0.06517 0.01657  77  CYS A CA  
942  C C   . CYS A 63  ? 0.08537 0.15351 0.16040 -0.00268 -0.06155 0.01740  77  CYS A C   
943  O O   . CYS A 63  ? 0.09285 0.15628 0.16375 -0.00217 -0.06135 0.01466  77  CYS A O   
944  C CB  . CYS A 63  ? 0.12827 0.15832 0.18310 0.00449  -0.05478 0.01276  77  CYS A CB  
945  S SG  . CYS A 63  ? 0.12503 0.16283 0.18807 -0.00318 -0.07729 0.00584  77  CYS A SG  
951  N N   . GLU A 64  ? 0.10088 0.15581 0.17644 -0.00534 -0.04635 0.02210  78  GLU A N   
952  C CA  A GLU A 64  ? 0.09748 0.15775 0.18534 -0.01324 -0.05181 0.01558  78  GLU A CA  
953  C CA  B GLU A 64  ? 0.09746 0.15837 0.19234 -0.01588 -0.06107 0.01494  78  GLU A CA  
954  C C   . GLU A 64  ? 0.10521 0.14782 0.17250 -0.01975 -0.04264 0.00912  78  GLU A C   
955  O O   . GLU A 64  ? 0.12482 0.15617 0.20009 -0.01085 -0.02575 0.02067  78  GLU A O   
956  C CB  A GLU A 64  ? 0.11632 0.17664 0.20760 -0.01698 -0.05449 0.01626  78  GLU A CB  
957  C CB  B GLU A 64  ? 0.12669 0.18067 0.22951 -0.02595 -0.07682 0.01275  78  GLU A CB  
958  C CG  A GLU A 64  ? 0.12730 0.18533 0.18886 -0.00202 -0.04528 0.02200  78  GLU A CG  
959  C CG  B GLU A 64  ? 0.13394 0.18381 0.20997 -0.01288 -0.06899 0.02476  78  GLU A CG  
960  C CD  A GLU A 64  ? 0.13064 0.19742 0.21247 0.00911  -0.05029 0.02876  78  GLU A CD  
961  C CD  B GLU A 64  ? 0.11368 0.18184 0.19244 -0.00057 -0.07928 0.01070  78  GLU A CD  
962  O OE1 A GLU A 64  ? 0.14576 0.20693 0.22044 0.02012  -0.06434 0.02716  78  GLU A OE1 
963  O OE1 B GLU A 64  ? 0.11174 0.18736 0.20076 0.01113  -0.07172 0.01124  78  GLU A OE1 
964  O OE2 A GLU A 64  ? 0.11950 0.20862 0.22437 0.01146  -0.03140 0.02916  78  GLU A OE2 
965  O OE2 B GLU A 64  ? 0.13370 0.18419 0.18487 0.01469  -0.06630 0.01610  78  GLU A OE2 
976  N N   . LEU A 65  ? 0.12193 0.14376 0.14339 -0.01590 -0.03515 0.00232  79  LEU A N   
977  C CA  . LEU A 65  ? 0.11790 0.15497 0.15261 -0.00512 -0.03945 0.00487  79  LEU A CA  
978  C C   . LEU A 65  ? 0.09814 0.16427 0.13376 -0.01002 -0.05284 0.00238  79  LEU A C   
979  O O   . LEU A 65  ? 0.10529 0.18936 0.16251 -0.02747 -0.03444 -0.01160 79  LEU A O   
980  C CB  . LEU A 65  ? 0.12399 0.15852 0.16342 -0.00987 -0.05303 0.01107  79  LEU A CB  
981  C CG  . LEU A 65  ? 0.12797 0.16960 0.15796 -0.00649 -0.03927 0.00268  79  LEU A CG  
982  C CD1 . LEU A 65  ? 0.13956 0.17398 0.16038 0.01217  -0.04453 0.01530  79  LEU A CD1 
983  C CD2 . LEU A 65  ? 0.12273 0.17525 0.17203 -0.01518 -0.05582 -0.00175 79  LEU A CD2 
995  N N   . ARG A 66  ? 0.10242 0.17936 0.13128 -0.01165 -0.03832 0.00094  80  ARG A N   
996  C CA  . ARG A 66  ? 0.09531 0.18455 0.15120 -0.00917 -0.04267 0.00707  80  ARG A CA  
997  C C   . ARG A 66  ? 0.09713 0.19047 0.15545 0.00410  -0.05068 -0.00355 80  ARG A C   
998  O O   . ARG A 66  ? 0.09324 0.19012 0.16633 -0.00612 -0.04522 -0.00122 80  ARG A O   
999  C CB  . ARG A 66  ? 0.10388 0.19243 0.15952 0.00282  -0.04468 0.00864  80  ARG A CB  
1000 C CG  . ARG A 66  ? 0.11689 0.20182 0.14380 0.00617  -0.05134 0.01377  80  ARG A CG  
1001 C CD  . ARG A 66  ? 0.12368 0.21809 0.14735 0.00054  -0.04549 0.01642  80  ARG A CD  
1002 N NE  . ARG A 66  ? 0.13203 0.21549 0.14155 -0.00738 -0.04477 0.00669  80  ARG A NE  
1003 C CZ  . ARG A 66  ? 0.11805 0.22754 0.14807 -0.01191 -0.04572 0.01064  80  ARG A CZ  
1004 N NH1 . ARG A 66  ? 0.12042 0.22459 0.15176 0.00196  -0.02832 0.00233  80  ARG A NH1 
1005 N NH2 . ARG A 66  ? 0.13691 0.24869 0.14838 -0.00814 -0.04034 0.02202  80  ARG A NH2 
1019 N N   . GLN A 67  ? 0.08249 0.18842 0.15546 0.01058  -0.04026 -0.00216 81  GLN A N   
1020 C CA  . GLN A 67  ? 0.09403 0.19756 0.14905 0.00003  -0.04027 0.00157  81  GLN A CA  
1021 C C   . GLN A 67  ? 0.09419 0.21539 0.14404 -0.00588 -0.05029 -0.01092 81  GLN A C   
1022 O O   . GLN A 67  ? 0.10347 0.22513 0.16559 -0.01471 -0.03886 -0.00694 81  GLN A O   
1023 C CB  . GLN A 67  ? 0.08758 0.19538 0.17265 0.00435  -0.04499 -0.00823 81  GLN A CB  
1024 C CG  . GLN A 67  ? 0.08796 0.20276 0.17249 -0.00090 -0.02733 -0.01730 81  GLN A CG  
1025 C CD  . GLN A 67  ? 0.10249 0.20691 0.17239 0.01340  -0.03147 -0.01479 81  GLN A CD  
1026 O OE1 . GLN A 67  ? 0.09811 0.20471 0.17752 0.00259  -0.03627 -0.01158 81  GLN A OE1 
1027 N NE2 . GLN A 67  ? 0.12264 0.21533 0.24969 0.01841  -0.03856 -0.03140 81  GLN A NE2 
1036 N N   . MET A 68  ? 0.08616 0.23093 0.16610 -0.00496 -0.03826 -0.00481 82  MET A N   
1037 C CA  . MET A 68  ? 0.09214 0.23745 0.18069 -0.01837 -0.02232 -0.00197 82  MET A CA  
1038 C C   . MET A 68  ? 0.10319 0.25705 0.17783 -0.01146 -0.02291 -0.01373 82  MET A C   
1039 O O   . MET A 68  ? 0.11125 0.25001 0.21081 0.00792  -0.01976 0.00400  82  MET A O   
1040 C CB  . MET A 68  ? 0.10477 0.23904 0.17635 -0.01938 -0.02519 0.00698  82  MET A CB  
1041 C CG  . MET A 68  ? 0.12914 0.23769 0.17569 -0.00806 -0.02452 0.00333  82  MET A CG  
1042 S SD  . MET A 68  ? 0.13131 0.23598 0.19348 -0.01453 -0.03534 0.01071  82  MET A SD  
1043 C CE  . MET A 68  ? 0.16819 0.24046 0.19792 -0.02471 -0.01801 0.03280  82  MET A CE  
1053 N N   . ILE A 69  ? 0.10886 0.28724 0.19027 -0.00071 -0.00792 -0.01566 83  ILE A N   
1054 C CA  . ILE A 69  ? 0.10858 0.31758 0.22218 -0.00459 -0.00361 -0.02585 83  ILE A CA  
1055 C C   . ILE A 69  ? 0.10624 0.31263 0.22030 0.00303  -0.01862 -0.03133 83  ILE A C   
1056 O O   . ILE A 69  ? 0.11003 0.30432 0.22208 -0.00272 -0.02859 -0.01715 83  ILE A O   
1057 C CB  . ILE A 69  ? 0.12265 0.34988 0.23086 -0.00224 -0.00194 -0.03295 83  ILE A CB  
1058 C CG1 . ILE A 69  ? 0.15801 0.37667 0.23232 -0.00112 0.00555  -0.04180 83  ILE A CG1 
1059 C CG2 . ILE A 69  ? 0.14795 0.35606 0.25339 0.00798  0.02498  -0.01798 83  ILE A CG2 
1060 C CD1 . ILE A 69  ? 0.20542 0.39474 0.23440 -0.01065 0.02267  -0.04035 83  ILE A CD1 
1072 N N   . PRO A 70  ? 0.13014 0.31937 0.24039 0.01014  -0.02029 -0.04039 84  PRO A N   
1073 C CA  . PRO A 70  ? 0.14199 0.33288 0.25965 0.01020  -0.02319 -0.02766 84  PRO A CA  
1074 C C   . PRO A 70  ? 0.11422 0.35679 0.25794 0.00541  -0.02212 -0.01169 84  PRO A C   
1075 O O   . PRO A 70  ? 0.13321 0.37628 0.24028 -0.00719 -0.00554 -0.01307 84  PRO A O   
1076 C CB  . PRO A 70  ? 0.17320 0.33266 0.27430 0.02661  -0.04010 -0.02154 84  PRO A CB  
1077 C CG  . PRO A 70  ? 0.20765 0.33024 0.29239 0.02088  -0.01979 -0.03929 84  PRO A CG  
1078 C CD  . PRO A 70  ? 0.18269 0.32147 0.26034 0.01679  -0.01647 -0.05053 84  PRO A CD  
1086 N N   . ASP A 71  ? 0.11855 0.36484 0.26478 0.01238  -0.03836 0.00587  85  ASP A N   
1087 C CA  . ASP A 71  ? 0.12095 0.37858 0.30132 0.02642  -0.04672 0.01862  85  ASP A CA  
1088 C C   . ASP A 71  ? 0.13031 0.38002 0.30484 0.00419  -0.02971 0.02200  85  ASP A C   
1089 O O   . ASP A 71  ? 0.16310 0.39101 0.35190 0.02155  0.02264  0.02828  85  ASP A O   
1090 C CB  . ASP A 71  ? 0.14381 0.40094 0.37494 0.05259  -0.00684 0.02395  85  ASP A CB  
1091 C CG  . ASP A 71  ? 0.20640 0.42488 0.46148 0.08675  0.04647  0.03620  85  ASP A CG  
1092 O OD1 . ASP A 71  ? 0.20076 0.43486 0.47178 0.10408  0.03515  0.05909  85  ASP A OD1 
1093 O OD2 . ASP A 71  ? 0.30693 0.44050 0.51976 0.06708  0.11398  0.02874  85  ASP A OD2 
1098 N N   . GLY A 72  ? 0.13296 0.37217 0.29223 -0.01205 -0.06476 0.03243  86  GLY A N   
1099 C CA  . GLY A 72  ? 0.14284 0.36837 0.30312 -0.02152 -0.04681 0.04010  86  GLY A CA  
1100 C C   . GLY A 72  ? 0.14435 0.36910 0.30538 -0.03209 -0.05188 0.04675  86  GLY A C   
1101 O O   . GLY A 72  ? 0.17379 0.37054 0.32063 -0.03744 -0.03448 0.05943  86  GLY A O   
1105 N N   . GLY A 73  ? 0.13080 0.36896 0.30117 -0.02677 -0.04819 0.03335  87  GLY A N   
1106 C CA  . GLY A 73  ? 0.12757 0.37022 0.26972 -0.00823 -0.05073 0.02547  87  GLY A CA  
1107 C C   . GLY A 73  ? 0.13313 0.36275 0.22309 -0.01384 -0.04658 0.02271  87  GLY A C   
1108 O O   . GLY A 73  ? 0.15902 0.35457 0.22594 -0.01496 -0.03589 0.03876  87  GLY A O   
1112 N N   . SER A 74  ? 0.14525 0.36583 0.22329 -0.01764 -0.02184 0.02939  88  SER A N   
1113 C CA  A SER A 74  ? 0.16059 0.36678 0.23610 -0.02002 -0.01813 0.03171  88  SER A CA  
1114 C CA  B SER A 74  ? 0.14996 0.35923 0.23268 -0.02658 -0.01282 0.03308  88  SER A CA  
1115 C C   . SER A 74  ? 0.13698 0.34441 0.20763 -0.02572 -0.01471 0.03007  88  SER A C   
1116 O O   . SER A 74  ? 0.13444 0.33674 0.22078 -0.01366 -0.02671 -0.00087 88  SER A O   
1117 C CB  A SER A 74  ? 0.20967 0.38688 0.26967 -0.00248 0.01032  0.03162  88  SER A CB  
1118 C CB  B SER A 74  ? 0.17248 0.36633 0.26362 -0.03043 0.00957  0.03797  88  SER A CB  
1119 O OG  A SER A 74  ? 0.24541 0.40261 0.27174 0.01631  0.02419  0.02227  88  SER A OG  
1120 O OG  B SER A 74  ? 0.18708 0.37152 0.27997 -0.03412 0.02495  0.03985  88  SER A OG  
1129 N N   . GLU A 75  ? 0.12933 0.32509 0.20809 -0.03123 -0.02359 0.03578  89  GLU A N   
1130 C CA  . GLU A 75  ? 0.12467 0.31495 0.19347 -0.03007 -0.03615 0.02972  89  GLU A CA  
1131 C C   . GLU A 75  ? 0.14459 0.31203 0.19304 -0.01648 -0.02073 0.02002  89  GLU A C   
1132 O O   . GLU A 75  ? 0.19359 0.31863 0.19933 -0.02457 -0.01563 0.01732  89  GLU A O   
1133 C CB  . GLU A 75  ? 0.13162 0.31653 0.19336 -0.03395 -0.04133 0.03437  89  GLU A CB  
1134 C CG  . GLU A 75  ? 0.15883 0.31367 0.20442 -0.02788 -0.02738 0.02507  89  GLU A CG  
1135 C CD  . GLU A 75  ? 0.19932 0.32147 0.23378 -0.02034 -0.00667 0.02642  89  GLU A CD  
1136 O OE1 . GLU A 75  ? 0.20823 0.31967 0.26057 -0.02845 -0.02059 0.02035  89  GLU A OE1 
1137 O OE2 . GLU A 75  ? 0.21546 0.33142 0.25779 -0.02191 -0.01177 0.02425  89  GLU A OE2 
1144 N N   . ILE A 76  ? 0.12826 0.29802 0.17438 -0.01739 -0.04475 -0.01065 90  ILE A N   
1145 C CA  . ILE A 76  ? 0.14876 0.29123 0.20643 -0.01183 -0.03151 -0.02218 90  ILE A CA  
1146 C C   . ILE A 76  ? 0.13777 0.28898 0.15430 -0.00968 -0.02435 -0.02520 90  ILE A C   
1147 O O   . ILE A 76  ? 0.13940 0.28769 0.16220 -0.00648 -0.04270 -0.01672 90  ILE A O   
1148 C CB  . ILE A 76  ? 0.17073 0.28569 0.22180 0.00462  -0.02307 -0.01906 90  ILE A CB  
1149 C CG1 . ILE A 76  ? 0.19056 0.28766 0.24030 0.01212  -0.03463 -0.02741 90  ILE A CG1 
1150 C CG2 . ILE A 76  ? 0.18184 0.27934 0.20089 0.01790  -0.03053 -0.01462 90  ILE A CG2 
1151 C CD1 . ILE A 76  ? 0.21904 0.29472 0.28162 0.02053  -0.04688 -0.03263 90  ILE A CD1 
1163 N N   . GLY A 77  ? 0.12631 0.28949 0.16737 -0.01650 -0.02772 -0.03080 91  GLY A N   
1164 C CA  . GLY A 77  ? 0.13466 0.30107 0.17229 -0.01812 -0.03081 -0.03161 91  GLY A CA  
1165 C C   . GLY A 77  ? 0.13076 0.30750 0.19069 -0.01290 -0.01229 -0.04046 91  GLY A C   
1166 O O   . GLY A 77  ? 0.16871 0.32530 0.22960 -0.03316 0.02035  -0.06073 91  GLY A O   
1170 N N   . TRP A 78  ? 0.12687 0.29507 0.16685 -0.00853 -0.02510 -0.04851 92  TRP A N   
1171 C CA  . TRP A 78  ? 0.13594 0.29189 0.17257 0.00155  -0.02034 -0.04508 92  TRP A CA  
1172 C C   . TRP A 78  ? 0.15272 0.30742 0.17370 -0.00261 -0.01534 -0.04401 92  TRP A C   
1173 O O   . TRP A 78  ? 0.16599 0.31841 0.18819 -0.00892 -0.02579 -0.04624 92  TRP A O   
1174 C CB  . TRP A 78  ? 0.13056 0.27878 0.20394 0.00766  -0.02496 -0.04471 92  TRP A CB  
1175 C CG  . TRP A 78  ? 0.12720 0.26307 0.19716 0.00591  -0.03470 -0.02916 92  TRP A CG  
1176 C CD1 . TRP A 78  ? 0.13326 0.25699 0.19288 -0.00007 -0.04296 -0.01881 92  TRP A CD1 
1177 C CD2 . TRP A 78  ? 0.12670 0.25373 0.17979 0.00307  -0.03143 -0.02977 92  TRP A CD2 
1178 N NE1 . TRP A 78  ? 0.13525 0.24452 0.17902 0.00775  -0.04208 -0.03339 92  TRP A NE1 
1179 C CE2 . TRP A 78  ? 0.12501 0.24405 0.18696 0.01083  -0.03303 -0.02798 92  TRP A CE2 
1180 C CE3 . TRP A 78  ? 0.13229 0.26240 0.19146 -0.01432 -0.03476 -0.03833 92  TRP A CE3 
1181 C CZ2 . TRP A 78  ? 0.13392 0.24454 0.16511 0.01153  -0.03525 -0.01822 92  TRP A CZ2 
1182 C CZ3 . TRP A 78  ? 0.13296 0.26423 0.18259 -0.01439 -0.03516 -0.03302 92  TRP A CZ3 
1183 C CH2 . TRP A 78  ? 0.13466 0.25813 0.19896 0.00432  -0.02146 -0.01664 92  TRP A CH2 
1194 N N   . ALA A 79  ? 0.15400 0.31507 0.21004 -0.00590 -0.02062 -0.04659 93  ALA A N   
1195 C CA  . ALA A 79  ? 0.15406 0.32797 0.19482 -0.01978 -0.05495 -0.04753 93  ALA A CA  
1196 C C   . ALA A 79  ? 0.16187 0.33041 0.20933 -0.02082 -0.04741 -0.05340 93  ALA A C   
1197 O O   . ALA A 79  ? 0.16812 0.33177 0.24738 -0.01872 -0.04165 -0.05184 93  ALA A O   
1198 C CB  . ALA A 79  ? 0.18126 0.33583 0.21896 -0.02897 -0.04423 -0.04745 93  ALA A CB  
1204 N N   . VAL A 80  ? 0.15784 0.33396 0.18824 -0.02162 -0.04904 -0.04386 94  VAL A N   
1205 C CA  . VAL A 80  ? 0.16866 0.33911 0.19264 -0.02210 -0.04694 -0.03716 94  VAL A CA  
1206 C C   . VAL A 80  ? 0.17518 0.36107 0.20976 -0.01742 -0.04526 -0.04760 94  VAL A C   
1207 O O   . VAL A 80  ? 0.18945 0.35949 0.21278 -0.01014 -0.04027 -0.04685 94  VAL A O   
1208 C CB  . VAL A 80  ? 0.17603 0.33037 0.17637 -0.02661 -0.03366 -0.02691 94  VAL A CB  
1209 C CG1 . VAL A 80  ? 0.18962 0.32929 0.18151 -0.02038 -0.02134 -0.02245 94  VAL A CG1 
1210 C CG2 . VAL A 80  ? 0.17904 0.32738 0.18323 -0.04405 -0.02313 -0.01584 94  VAL A CG2 
1220 N N   . ASP A 81  ? 0.20867 0.38455 0.19811 -0.02477 -0.03635 -0.06387 95  ASP A N   
1221 C CA  . ASP A 81  ? 0.23473 0.41341 0.21877 -0.02752 -0.02989 -0.08817 95  ASP A CA  
1222 C C   . ASP A 81  ? 0.25141 0.43164 0.23131 -0.01414 -0.01773 -0.11208 95  ASP A C   
1223 O O   . ASP A 81  ? 0.26815 0.44433 0.26165 -0.00502 -0.01899 -0.12176 95  ASP A O   
1224 C CB  . ASP A 81  ? 0.23639 0.42708 0.22893 -0.02809 -0.06401 -0.07304 95  ASP A CB  
1225 C CG  . ASP A 81  ? 0.26996 0.44135 0.23724 -0.03651 -0.07030 -0.08025 95  ASP A CG  
1226 O OD1 . ASP A 81  ? 0.30206 0.44713 0.22881 -0.04864 -0.05467 -0.07435 95  ASP A OD1 
1227 O OD2 . ASP A 81  ? 0.27844 0.44940 0.26431 -0.02751 -0.05799 -0.07836 95  ASP A OD2 
1232 N N   . ASP A 82  ? 0.25060 0.44281 0.24832 -0.00614 -0.01066 -0.10073 96  ASP A N   
1233 C CA  . ASP A 82  ? 0.25776 0.45055 0.26950 0.00499  -0.00534 -0.10303 96  ASP A CA  
1234 C C   . ASP A 82  ? 0.28708 0.46155 0.29184 0.02130  -0.00022 -0.08942 96  ASP A C   
1235 O O   . ASP A 82  ? 0.31124 0.46760 0.33781 0.03516  0.02423  -0.06596 96  ASP A O   
1236 C CB  . ASP A 82  ? 0.25337 0.44921 0.26810 0.00528  -0.00843 -0.10618 96  ASP A CB  
1237 C CG  . ASP A 82  ? 0.24819 0.44715 0.26980 0.00752  -0.01694 -0.10383 96  ASP A CG  
1238 O OD1 . ASP A 82  ? 0.25880 0.44323 0.26523 0.01490  -0.00951 -0.08480 96  ASP A OD1 
1239 O OD2 . ASP A 82  ? 0.25080 0.44749 0.28149 0.00627  -0.00722 -0.10925 96  ASP A OD2 
1244 N N   . GLY A 83  ? 0.30995 0.46197 0.28828 0.02129  -0.03363 -0.10289 97  GLY A N   
1245 C CA  . GLY A 83  ? 0.32787 0.45829 0.29948 0.02940  -0.04101 -0.10164 97  GLY A CA  
1246 C C   . GLY A 83  ? 0.32799 0.45659 0.33807 0.03401  -0.03856 -0.09293 97  GLY A C   
1247 O O   . GLY A 83  ? 0.36124 0.46072 0.37879 0.03654  -0.03873 -0.08186 97  GLY A O   
1251 N N   . THR A 84  ? 0.28546 0.44640 0.31746 0.04470  -0.02793 -0.09885 98  THR A N   
1252 C CA  . THR A 84  ? 0.25673 0.43358 0.32069 0.05075  -0.03644 -0.09987 98  THR A CA  
1253 C C   . THR A 84  ? 0.22200 0.39396 0.29798 0.07408  -0.04485 -0.11001 98  THR A C   
1254 O O   . THR A 84  ? 0.22294 0.40520 0.28454 0.07688  -0.04770 -0.09962 98  THR A O   
1255 C CB  . THR A 84  ? 0.27162 0.45947 0.36501 0.02899  -0.01654 -0.09429 98  THR A CB  
1256 O OG1 . THR A 84  ? 0.29239 0.47169 0.42077 0.02203  -0.00288 -0.08120 98  THR A OG1 
1257 C CG2 . THR A 84  ? 0.26888 0.46685 0.36763 0.01454  -0.02564 -0.09413 98  THR A CG2 
1265 N N   . THR A 85  ? 0.19495 0.34567 0.28733 0.09208  -0.05834 -0.10714 99  THR A N   
1266 C CA  . THR A 85  ? 0.19219 0.31326 0.27722 0.07553  -0.05990 -0.10422 99  THR A CA  
1267 C C   . THR A 85  ? 0.14706 0.29431 0.27206 0.05812  -0.06344 -0.08052 99  THR A C   
1268 O O   . THR A 85  ? 0.14261 0.31004 0.32187 0.05808  -0.06001 -0.08351 99  THR A O   
1269 C CB  . THR A 85  ? 0.24183 0.30684 0.31135 0.06396  -0.07385 -0.10160 99  THR A CB  
1270 O OG1 . THR A 85  ? 0.28839 0.30713 0.34841 0.05351  -0.06453 -0.11420 99  THR A OG1 
1271 C CG2 . THR A 85  ? 0.24888 0.31209 0.32661 0.05052  -0.07675 -0.07889 99  THR A CG2 
1279 N N   . HIS A 86  ? 0.13053 0.26380 0.22221 0.03737  -0.04951 -0.04478 100 HIS A N   
1280 C CA  . HIS A 86  ? 0.12925 0.25307 0.19102 0.01619  -0.03848 -0.04736 100 HIS A CA  
1281 C C   . HIS A 86  ? 0.10221 0.24344 0.19252 0.00969  -0.05220 -0.05855 100 HIS A C   
1282 O O   . HIS A 86  ? 0.10745 0.26120 0.20522 0.00178  -0.05190 -0.04680 100 HIS A O   
1283 C CB  . HIS A 86  ? 0.15342 0.25928 0.21952 0.00172  -0.01422 -0.03080 100 HIS A CB  
1284 C CG  . HIS A 86  ? 0.20439 0.27540 0.25537 0.00945  0.00625  -0.02481 100 HIS A CG  
1285 N ND1 . HIS A 86  ? 0.21178 0.28836 0.27726 0.01635  0.00893  -0.00826 100 HIS A ND1 
1286 C CD2 . HIS A 86  ? 0.24915 0.28729 0.26053 0.01539  0.02024  -0.01911 100 HIS A CD2 
1287 C CE1 . HIS A 86  ? 0.23302 0.29633 0.27223 0.02050  0.01998  -0.01066 100 HIS A CE1 
1288 N NE2 . HIS A 86  ? 0.25438 0.29592 0.27914 0.02004  0.03491  -0.01859 100 HIS A NE2 
1296 N N   . THR A 87  ? 0.09649 0.22787 0.19471 0.00427  -0.03663 -0.04835 101 THR A N   
1297 C CA  . THR A 87  ? 0.10597 0.21481 0.19491 0.01196  -0.04360 -0.04722 101 THR A CA  
1298 C C   . THR A 87  ? 0.09868 0.21835 0.18589 0.00441  -0.05760 -0.04938 101 THR A C   
1299 O O   . THR A 87  ? 0.09213 0.24542 0.23259 -0.00541 -0.04423 -0.06088 101 THR A O   
1300 C CB  . THR A 87  ? 0.16742 0.21308 0.21704 0.01936  -0.04369 -0.04545 101 THR A CB  
1301 O OG1 . THR A 87  ? 0.20004 0.22746 0.24142 0.02669  -0.04792 -0.04715 101 THR A OG1 
1302 C CG2 . THR A 87  ? 0.19620 0.20999 0.22980 0.01844  -0.03715 -0.02939 101 THR A CG2 
1310 N N   . ALA A 88  ? 0.09876 0.20832 0.17655 0.00937  -0.04653 -0.04152 102 ALA A N   
1311 C CA  . ALA A 88  ? 0.09455 0.20530 0.16488 0.00782  -0.04464 -0.03043 102 ALA A CA  
1312 C C   . ALA A 88  ? 0.07780 0.20681 0.18012 0.00142  -0.05305 -0.01517 102 ALA A C   
1313 O O   . ALA A 88  ? 0.11178 0.23185 0.17376 -0.03145 -0.06800 -0.01163 102 ALA A O   
1314 C CB  . ALA A 88  ? 0.10391 0.20123 0.18894 0.00109  -0.04882 -0.03324 102 ALA A CB  
1320 N N   . THR A 89  ? 0.08815 0.19112 0.16862 -0.00337 -0.05347 -0.01570 103 THR A N   
1321 C CA  . THR A 89  ? 0.08830 0.19083 0.17597 0.00554  -0.05011 -0.01123 103 THR A CA  
1322 C C   . THR A 89  ? 0.08120 0.18624 0.16127 -0.00933 -0.05745 -0.01378 103 THR A C   
1323 O O   . THR A 89  ? 0.10749 0.20158 0.17808 -0.02244 -0.04018 -0.03285 103 THR A O   
1324 C CB  . THR A 89  ? 0.11474 0.20628 0.20402 0.01600  -0.05740 -0.01667 103 THR A CB  
1325 O OG1 . THR A 89  ? 0.12066 0.22222 0.24709 0.02164  -0.05954 -0.01870 103 THR A OG1 
1326 C CG2 . THR A 89  ? 0.14763 0.21263 0.24117 0.02188  -0.05287 -0.02254 103 THR A CG2 
1334 N N   . SER A 90  ? 0.09148 0.17210 0.15981 -0.01135 -0.04766 -0.01151 104 SER A N   
1335 C CA  . SER A 90  ? 0.08513 0.16194 0.15656 -0.00035 -0.06059 -0.01806 104 SER A CA  
1336 C C   . SER A 90  ? 0.08919 0.16044 0.15970 -0.00308 -0.06537 -0.00451 104 SER A C   
1337 O O   . SER A 90  ? 0.10381 0.16296 0.16495 -0.01086 -0.06192 -0.00044 104 SER A O   
1338 C CB  . SER A 90  ? 0.08715 0.17281 0.16679 0.01319  -0.05433 0.00019  104 SER A CB  
1339 O OG  . SER A 90  ? 0.08818 0.18540 0.17716 0.00625  -0.04903 0.00758  104 SER A OG  
1345 N N   . SER A 91  ? 0.10268 0.15400 0.16059 -0.00160 -0.07158 0.00198  105 SER A N   
1346 C CA  . SER A 91  ? 0.10234 0.15007 0.15859 0.00150  -0.05787 0.00899  105 SER A CA  
1347 C C   . SER A 91  ? 0.08992 0.14378 0.14558 -0.00140 -0.05796 0.00041  105 SER A C   
1348 O O   . SER A 91  ? 0.09345 0.14437 0.16790 -0.00790 -0.05712 -0.00777 105 SER A O   
1349 C CB  . SER A 91  ? 0.12241 0.16061 0.16428 0.00325  -0.05693 0.01412  105 SER A CB  
1350 O OG  . SER A 91  ? 0.14526 0.18912 0.19765 0.00697  -0.06400 0.02226  105 SER A OG  
1356 N N   . ILE A 92  ? 0.10051 0.13819 0.15716 -0.00572 -0.05180 -0.00506 106 ILE A N   
1357 C CA  . ILE A 92  ? 0.10038 0.14784 0.15628 -0.00243 -0.04849 0.00215  106 ILE A CA  
1358 C C   . ILE A 92  ? 0.10391 0.14465 0.15451 -0.00695 -0.04887 0.00249  106 ILE A C   
1359 O O   . ILE A 92  ? 0.13143 0.13702 0.16714 -0.01512 -0.04932 0.00816  106 ILE A O   
1360 C CB  . ILE A 92  ? 0.10870 0.16843 0.14554 0.00505  -0.05884 0.00604  106 ILE A CB  
1361 C CG1 . ILE A 92  ? 0.09943 0.17619 0.16117 0.01852  -0.05671 0.01065  106 ILE A CG1 
1362 C CG2 . ILE A 92  ? 0.15169 0.17650 0.14888 0.02287  -0.04109 -0.00298 106 ILE A CG2 
1363 C CD1 . ILE A 92  ? 0.11564 0.17857 0.15424 0.01906  -0.04944 -0.00532 106 ILE A CD1 
1375 N N   . VAL A 93  ? 0.11068 0.15602 0.14972 0.00218  -0.03971 0.00369  107 VAL A N   
1376 C CA  . VAL A 93  ? 0.11807 0.17651 0.15673 0.00327  -0.05036 0.00247  107 VAL A CA  
1377 C C   . VAL A 93  ? 0.11518 0.17213 0.15148 0.00576  -0.04571 0.00621  107 VAL A C   
1378 O O   . VAL A 93  ? 0.10996 0.16444 0.19647 0.00734  -0.03902 -0.00528 107 VAL A O   
1379 C CB  . VAL A 93  ? 0.15414 0.19287 0.16441 -0.00186 -0.05545 0.00026  107 VAL A CB  
1380 C CG1 . VAL A 93  ? 0.18683 0.21263 0.16533 0.00438  -0.05540 -0.01952 107 VAL A CG1 
1381 C CG2 . VAL A 93  ? 0.16708 0.20127 0.16819 0.00097  -0.06855 -0.00030 107 VAL A CG2 
1391 N N   . VAL A 94  ? 0.10762 0.17303 0.16723 0.00045  -0.04692 0.00621  108 VAL A N   
1392 C CA  . VAL A 94  ? 0.10007 0.19895 0.16707 0.00202  -0.03453 0.02279  108 VAL A CA  
1393 C C   . VAL A 94  ? 0.11617 0.20875 0.17411 0.00715  -0.04010 0.01861  108 VAL A C   
1394 O O   . VAL A 94  ? 0.13139 0.20656 0.19510 0.00139  -0.01467 0.01343  108 VAL A O   
1395 C CB  . VAL A 94  ? 0.11305 0.21181 0.18289 -0.00664 -0.03993 0.02396  108 VAL A CB  
1396 C CG1 . VAL A 94  ? 0.12046 0.21778 0.20782 -0.00040 -0.05836 0.04206  108 VAL A CG1 
1397 C CG2 . VAL A 94  ? 0.14415 0.21759 0.17738 -0.02850 -0.04402 0.00716  108 VAL A CG2 
1407 N N   A PRO A 95  ? 0.13758 0.21291 0.17750 0.00569  -0.04068 0.00522  109 PRO A N   
1408 N N   B PRO A 95  ? 0.14583 0.22139 0.19262 0.00671  -0.01836 0.00796  109 PRO A N   
1409 C CA  A PRO A 95  ? 0.16681 0.22272 0.17894 -0.00319 -0.01895 -0.00487 109 PRO A CA  
1410 C CA  B PRO A 95  ? 0.16365 0.23164 0.20047 0.00716  -0.00610 0.00365  109 PRO A CA  
1411 C C   A PRO A 95  ? 0.15498 0.22721 0.19585 0.01142  -0.01259 0.00318  109 PRO A C   
1412 C C   B PRO A 95  ? 0.16988 0.24254 0.19935 0.01263  -0.00299 0.00353  109 PRO A C   
1413 O O   A PRO A 95  ? 0.13740 0.21754 0.19912 0.01446  -0.01811 0.00769  109 PRO A O   
1414 O O   B PRO A 95  ? 0.17066 0.24261 0.19698 0.01282  -0.00608 0.00243  109 PRO A O   
1415 C CB  A PRO A 95  ? 0.18940 0.23140 0.20337 -0.01209 -0.02524 -0.01763 109 PRO A CB  
1416 C CB  B PRO A 95  ? 0.17027 0.23111 0.20943 0.00440  -0.00156 0.00077  109 PRO A CB  
1417 C CG  A PRO A 95  ? 0.21708 0.23037 0.23745 -0.02268 -0.00274 -0.01612 109 PRO A CG  
1418 C CG  B PRO A 95  ? 0.17258 0.22856 0.21265 0.00207  0.00145  0.00047  109 PRO A CG  
1419 C CD  A PRO A 95  ? 0.16610 0.21903 0.18991 -0.01005 -0.04902 -0.00595 109 PRO A CD  
1420 C CD  B PRO A 95  ? 0.16058 0.22474 0.20341 0.00429  -0.00783 0.00349  109 PRO A CD  
1435 N N   . GLU A 96  ? 0.17483 0.25372 0.20008 0.01744  0.00240  0.00492  110 GLU A N   
1436 C CA  . GLU A 96  ? 0.20179 0.28730 0.23316 0.02407  0.01805  0.00369  110 GLU A CA  
1437 C C   . GLU A 96  ? 0.18105 0.27786 0.22424 0.03008  -0.01148 -0.00304 110 GLU A C   
1438 O O   . GLU A 96  ? 0.20133 0.28153 0.25962 0.02526  -0.04557 0.00295  110 GLU A O   
1439 C CB  . GLU A 96  ? 0.28300 0.34219 0.31311 0.02218  0.08508  0.00263  110 GLU A CB  
1440 C CG  . GLU A 96  ? 0.39335 0.39751 0.43738 0.00980  0.14477  0.00469  110 GLU A CG  
1441 C CD  . GLU A 96  ? 0.48644 0.43983 0.55067 -0.00208 0.18304  0.01467  110 GLU A CD  
1442 O OE1 . GLU A 96  ? 0.53011 0.45635 0.58094 -0.01220 0.19239  0.02163  110 GLU A OE1 
1443 O OE2 . GLU A 96  ? 0.51816 0.45583 0.59688 -0.00431 0.19249  0.01427  110 GLU A OE2 
1450 N N   . GLN A 97  ? 0.17326 0.27233 0.19865 0.02562  0.00523  -0.00528 111 GLN A N   
1451 C CA  . GLN A 97  ? 0.15690 0.27292 0.20301 0.03092  -0.00936 -0.00547 111 GLN A CA  
1452 C C   . GLN A 97  ? 0.17036 0.28557 0.21509 0.04113  -0.01029 -0.01907 111 GLN A C   
1453 O O   . GLN A 97  ? 0.17738 0.29965 0.25206 0.04108  0.00827  -0.01490 111 GLN A O   
1454 C CB  . GLN A 97  ? 0.13166 0.26507 0.20570 0.02628  -0.01700 -0.00331 111 GLN A CB  
1455 C CG  . GLN A 97  ? 0.13563 0.24194 0.18206 0.02797  -0.04128 -0.00205 111 GLN A CG  
1456 C CD  . GLN A 97  ? 0.13072 0.21416 0.19016 0.02889  -0.03336 0.00174  111 GLN A CD  
1457 O OE1 . GLN A 97  ? 0.15499 0.20506 0.20976 0.03040  -0.03059 0.01881  111 GLN A OE1 
1458 N NE2 . GLN A 97  ? 0.12498 0.20477 0.22220 0.01826  -0.03686 0.00059  111 GLN A NE2 
1467 N N   . VAL A 98  ? 0.18932 0.28265 0.21798 0.05885  -0.01024 -0.02189 112 VAL A N   
1468 C CA  . VAL A 98  ? 0.20305 0.28241 0.26349 0.06447  -0.01353 -0.04250 112 VAL A CA  
1469 C C   . VAL A 98  ? 0.20819 0.28379 0.27183 0.07287  -0.00899 -0.04175 112 VAL A C   
1470 O O   . VAL A 98  ? 0.18850 0.28279 0.26334 0.06602  -0.02781 -0.04473 112 VAL A O   
1471 C CB  . VAL A 98  ? 0.23259 0.29121 0.29102 0.04641  -0.02449 -0.05221 112 VAL A CB  
1472 C CG1 . VAL A 98  ? 0.23565 0.30145 0.30122 0.04670  -0.04898 -0.05293 112 VAL A CG1 
1473 C CG2 . VAL A 98  ? 0.22695 0.28222 0.29509 0.05291  -0.00925 -0.05571 112 VAL A CG2 
1483 N N   . ASP A 99  ? 0.23190 0.29704 0.29935 0.08861  0.02645  -0.04083 113 ASP A N   
1484 C CA  . ASP A 99  ? 0.23352 0.31488 0.33204 0.09538  0.04213  -0.03594 113 ASP A CA  
1485 C C   . ASP A 99  ? 0.20711 0.30335 0.31485 0.08951  -0.00734 -0.02971 113 ASP A C   
1486 O O   . ASP A 99  ? 0.23152 0.30750 0.33993 0.07345  -0.00458 -0.03046 113 ASP A O   
1487 C CB  . ASP A 99  ? 0.29572 0.34484 0.40209 0.09718  0.09318  -0.03542 113 ASP A CB  
1488 C CG  . ASP A 99  ? 0.37292 0.37828 0.48810 0.08387  0.13292  -0.03379 113 ASP A CG  
1489 O OD1 . ASP A 99  ? 0.39595 0.39038 0.51355 0.06876  0.13735  -0.02706 113 ASP A OD1 
1490 O OD2 . ASP A 99  ? 0.41865 0.39578 0.52532 0.07465  0.15817  -0.03697 113 ASP A OD2 
1495 N N   . GLY A 100 ? 0.19895 0.29178 0.29965 0.09349  -0.00617 -0.03243 114 GLY A N   
1496 C CA  . GLY A 100 ? 0.20194 0.27309 0.28916 0.08680  0.00565  -0.02061 114 GLY A CA  
1497 C C   . GLY A 100 ? 0.18664 0.25035 0.28056 0.07587  0.00689  -0.00796 114 GLY A C   
1498 O O   . GLY A 100 ? 0.19605 0.25118 0.28506 0.08848  -0.00310 0.00740  114 GLY A O   
1502 N N   . VAL A 101 ? 0.15367 0.23506 0.25704 0.06771  -0.00354 -0.00245 115 VAL A N   
1503 C CA  . VAL A 101 ? 0.14136 0.22057 0.26036 0.04739  -0.00953 -0.00329 115 VAL A CA  
1504 C C   . VAL A 101 ? 0.12093 0.22619 0.26356 0.03210  -0.01239 -0.00684 115 VAL A C   
1505 O O   . VAL A 101 ? 0.15434 0.24142 0.27527 0.02088  -0.00779 0.00262  115 VAL A O   
1506 C CB  . VAL A 101 ? 0.14211 0.21691 0.24294 0.03794  -0.03007 -0.01075 115 VAL A CB  
1507 C CG1 . VAL A 101 ? 0.14164 0.20726 0.21879 0.03278  -0.03099 -0.02315 115 VAL A CG1 
1508 C CG2 . VAL A 101 ? 0.16771 0.23210 0.24773 0.03707  -0.03329 -0.03728 115 VAL A CG2 
1518 N N   . GLU A 102 ? 0.10554 0.22006 0.25726 0.03195  -0.01191 -0.01507 116 GLU A N   
1519 C CA  . GLU A 102 ? 0.09701 0.22179 0.30058 0.02559  -0.02532 -0.00797 116 GLU A CA  
1520 C C   . GLU A 102 ? 0.08440 0.20456 0.28354 0.01527  -0.03285 -0.00128 116 GLU A C   
1521 O O   . GLU A 102 ? 0.09465 0.20627 0.29452 0.01047  -0.03982 0.00761  116 GLU A O   
1522 C CB  . GLU A 102 ? 0.13053 0.23983 0.36387 0.03573  -0.04106 -0.01665 116 GLU A CB  
1523 C CG  . GLU A 102 ? 0.18567 0.26051 0.46052 0.05815  0.01264  0.00084  116 GLU A CG  
1524 C CD  . GLU A 102 ? 0.26689 0.28530 0.57210 0.06416  0.09988  -0.00070 116 GLU A CD  
1525 O OE1 . GLU A 102 ? 0.28563 0.31150 0.62454 0.05651  0.13803  0.00583  116 GLU A OE1 
1526 O OE2 . GLU A 102 ? 0.33085 0.29971 0.60740 0.05375  0.12342  -0.00566 116 GLU A OE2 
1533 N N   . GLU A 103 ? 0.08927 0.19378 0.26642 0.02070  -0.03912 0.00439  117 GLU A N   
1534 C CA  . GLU A 103 ? 0.08627 0.19041 0.24230 0.02103  -0.05499 0.00433  117 GLU A CA  
1535 C C   . GLU A 103 ? 0.09101 0.17802 0.19923 0.02070  -0.05716 -0.00477 117 GLU A C   
1536 O O   . GLU A 103 ? 0.11013 0.16958 0.23057 0.02089  -0.05541 0.00818  117 GLU A O   
1537 C CB  . GLU A 103 ? 0.10604 0.20617 0.25490 0.02149  -0.06468 0.00900  117 GLU A CB  
1538 C CG  . GLU A 103 ? 0.11976 0.22353 0.25651 0.02288  -0.07979 0.00470  117 GLU A CG  
1539 C CD  . GLU A 103 ? 0.13822 0.24597 0.27878 0.03354  -0.09724 -0.00071 117 GLU A CD  
1540 O OE1 . GLU A 103 ? 0.17139 0.26335 0.30073 0.05946  -0.10182 0.01313  117 GLU A OE1 
1541 O OE2 . GLU A 103 ? 0.13690 0.24662 0.26286 0.03235  -0.09628 0.00150  117 GLU A OE2 
1548 N N   . VAL A 104 ? 0.07721 0.16460 0.18752 0.01784  -0.04844 -0.00657 118 VAL A N   
1549 C CA  . VAL A 104 ? 0.08725 0.16643 0.18551 0.00806  -0.06448 -0.00884 118 VAL A CA  
1550 C C   . VAL A 104 ? 0.07854 0.15210 0.16652 0.00649  -0.05819 -0.00594 118 VAL A C   
1551 O O   . VAL A 104 ? 0.08944 0.15459 0.16910 0.00365  -0.05296 -0.00248 118 VAL A O   
1552 C CB  . VAL A 104 ? 0.09601 0.16789 0.17269 0.00269  -0.06931 -0.01223 118 VAL A CB  
1553 C CG1 . VAL A 104 ? 0.08878 0.17067 0.18685 0.00570  -0.06086 -0.01127 118 VAL A CG1 
1554 C CG2 . VAL A 104 ? 0.12296 0.17001 0.18051 0.00213  -0.03978 -0.01787 118 VAL A CG2 
1564 N N   . THR A 105 ? 0.07975 0.14834 0.15990 0.01644  -0.04355 0.00132  119 THR A N   
1565 C CA  . THR A 105 ? 0.07852 0.15701 0.15097 0.00168  -0.05139 0.00517  119 THR A CA  
1566 C C   . THR A 105 ? 0.08349 0.14955 0.15660 -0.00902 -0.02921 -0.00488 119 THR A C   
1567 O O   . THR A 105 ? 0.08434 0.15507 0.17552 0.00132  -0.05947 0.01338  119 THR A O   
1568 C CB  . THR A 105 ? 0.09211 0.17205 0.15858 0.00706  -0.06289 0.00507  119 THR A CB  
1569 O OG1 . THR A 105 ? 0.10556 0.19043 0.17365 0.02102  -0.07330 0.00317  119 THR A OG1 
1570 C CG2 . THR A 105 ? 0.10756 0.17972 0.16202 0.01209  -0.06280 0.00129  119 THR A CG2 
1578 N N   . ILE A 106 ? 0.07919 0.13754 0.14603 -0.00350 -0.04446 -0.00196 120 ILE A N   
1579 C CA  . ILE A 106 ? 0.07208 0.15245 0.13506 0.00264  -0.05296 -0.00410 120 ILE A CA  
1580 C C   . ILE A 106 ? 0.07616 0.15824 0.12317 0.00684  -0.05320 0.00034  120 ILE A C   
1581 O O   . ILE A 106 ? 0.07317 0.16525 0.13490 0.00320  -0.05343 0.00413  120 ILE A O   
1582 C CB  . ILE A 106 ? 0.08407 0.16386 0.14291 0.00415  -0.04928 0.00214  120 ILE A CB  
1583 C CG1 . ILE A 106 ? 0.08660 0.17288 0.15018 0.00022  -0.04413 0.00890  120 ILE A CG1 
1584 C CG2 . ILE A 106 ? 0.11604 0.18193 0.14138 0.00151  -0.03585 -0.00311 120 ILE A CG2 
1585 C CD1 . ILE A 106 ? 0.10312 0.17699 0.16360 -0.00952 -0.02859 0.01567  120 ILE A CD1 
1597 N N   . MET A 107 ? 0.07945 0.16399 0.13572 0.00738  -0.05172 -0.00626 121 MET A N   
1598 C CA  . MET A 107 ? 0.08277 0.16614 0.13380 0.00784  -0.05306 0.00016  121 MET A CA  
1599 C C   . MET A 107 ? 0.07692 0.16337 0.13067 -0.00291 -0.05563 0.00076  121 MET A C   
1600 O O   . MET A 107 ? 0.07207 0.17955 0.14906 -0.00568 -0.05239 -0.00345 121 MET A O   
1601 C CB  . MET A 107 ? 0.08267 0.17329 0.14175 0.01266  -0.05137 0.00373  121 MET A CB  
1602 C CG  . MET A 107 ? 0.09550 0.17174 0.16331 0.01933  -0.05562 0.01468  121 MET A CG  
1603 S SD  . MET A 107 ? 0.10933 0.18037 0.17635 0.01443  -0.06574 -0.00264 121 MET A SD  
1604 C CE  . MET A 107 ? 0.12738 0.19783 0.21241 0.03471  -0.04689 0.00019  121 MET A CE  
1614 N N   . GLN A 108 ? 0.07814 0.18448 0.12177 0.00047  -0.04814 0.00696  122 GLN A N   
1615 C CA  . GLN A 108 ? 0.09603 0.18470 0.14148 -0.00089 -0.05056 0.00663  122 GLN A CA  
1616 C C   . GLN A 108 ? 0.08531 0.19022 0.12702 -0.00650 -0.05191 0.01766  122 GLN A C   
1617 O O   . GLN A 108 ? 0.08656 0.20233 0.14378 -0.00640 -0.05683 0.00598  122 GLN A O   
1618 C CB  . GLN A 108 ? 0.10291 0.19177 0.16811 0.01288  -0.07087 0.00479  122 GLN A CB  
1619 C CG  . GLN A 108 ? 0.11620 0.19957 0.17496 0.00956  -0.04889 0.00768  122 GLN A CG  
1620 C CD  . GLN A 108 ? 0.12851 0.20297 0.22690 0.01013  -0.09376 0.00073  122 GLN A CD  
1621 O OE1 . GLN A 108 ? 0.16599 0.21059 0.26914 0.00399  -0.11880 0.01316  122 GLN A OE1 
1622 N NE2 . GLN A 108 ? 0.12223 0.21251 0.23499 0.00824  -0.08305 0.00266  122 GLN A NE2 
1631 N N   . ILE A 109 ? 0.08863 0.20751 0.12757 -0.01295 -0.05083 -0.00523 123 ILE A N   
1632 C CA  . ILE A 109 ? 0.09689 0.22397 0.12855 -0.00349 -0.04591 -0.00777 123 ILE A CA  
1633 C C   . ILE A 109 ? 0.10302 0.23208 0.14047 -0.00775 -0.03728 0.00241  123 ILE A C   
1634 O O   . ILE A 109 ? 0.09631 0.22897 0.15122 -0.00651 -0.05875 0.01481  123 ILE A O   
1635 C CB  . ILE A 109 ? 0.10331 0.22412 0.13794 0.01827  -0.05072 -0.01410 123 ILE A CB  
1636 C CG1 . ILE A 109 ? 0.12264 0.20996 0.16278 0.02310  -0.04583 -0.01554 123 ILE A CG1 
1637 C CG2 . ILE A 109 ? 0.11007 0.23670 0.15257 0.01814  -0.03827 -0.01225 123 ILE A CG2 
1638 C CD1 . ILE A 109 ? 0.16461 0.20663 0.17523 0.01383  -0.03152 -0.02379 123 ILE A CD1 
1650 N N   . ASN A 110 ? 0.09823 0.23707 0.15958 0.00163  -0.05921 0.02156  124 ASN A N   
1651 C CA  A ASN A 110 ? 0.10041 0.23872 0.17122 -0.00431 -0.06547 0.01347  124 ASN A CA  
1652 C CA  B ASN A 110 ? 0.11081 0.23932 0.16150 -0.00576 -0.05472 0.01615  124 ASN A CA  
1653 C C   . ASN A 110 ? 0.11800 0.24961 0.16306 -0.00853 -0.06212 0.01163  124 ASN A C   
1654 O O   . ASN A 110 ? 0.11357 0.24627 0.15719 0.00226  -0.04890 0.01871  124 ASN A O   
1655 C CB  A ASN A 110 ? 0.13006 0.23471 0.19421 -0.00642 -0.05497 0.00371  124 ASN A CB  
1656 C CB  B ASN A 110 ? 0.14779 0.22827 0.16302 -0.00896 -0.03500 0.01209  124 ASN A CB  
1657 C CG  A ASN A 110 ? 0.14857 0.23359 0.25298 -0.01079 -0.05089 -0.00586 124 ASN A CG  
1658 C CG  B ASN A 110 ? 0.15122 0.22293 0.19015 -0.01583 -0.05267 0.00820  124 ASN A CG  
1659 O OD1 A ASN A 110 ? 0.14544 0.23227 0.26376 -0.00668 -0.05945 0.00481  124 ASN A OD1 
1660 O OD1 B ASN A 110 ? 0.15494 0.22197 0.23499 -0.01420 -0.06029 0.00421  124 ASN A OD1 
1661 N ND2 A ASN A 110 ? 0.18684 0.24198 0.29358 -0.00787 -0.04665 -0.01686 124 ASN A ND2 
1662 N ND2 B ASN A 110 ? 0.12882 0.22190 0.17774 -0.02030 -0.07902 0.01072  124 ASN A ND2 
1665 N N   . SER A 111 ? 0.14462 0.27375 0.14969 0.00619  -0.04601 0.01726  125 SER A N   
1666 C CA  . SER A 111 ? 0.14760 0.29309 0.15324 -0.01381 -0.06536 0.03399  125 SER A CA  
1667 C C   . SER A 111 ? 0.17926 0.30125 0.17119 -0.01538 -0.06089 0.04823  125 SER A C   
1668 O O   . SER A 111 ? 0.22427 0.28752 0.19703 0.00033  -0.04467 0.04333  125 SER A O   
1669 C CB  . SER A 111 ? 0.14026 0.30075 0.19314 -0.02410 -0.06106 0.02385  125 SER A CB  
1670 O OG  . SER A 111 ? 0.14886 0.31180 0.21335 -0.02571 -0.07857 0.01245  125 SER A OG  
1676 N N   . GLY A 112 ? 0.20283 0.32538 0.19381 -0.02056 -0.04072 0.06781  126 GLY A N   
1677 C CA  . GLY A 112 ? 0.25731 0.35907 0.23159 -0.01663 -0.05223 0.10780  126 GLY A CA  
1678 C C   . GLY A 112 ? 0.30939 0.39931 0.30901 0.00974  -0.04053 0.15496  126 GLY A C   
1679 O O   . GLY A 112 ? 0.34611 0.41358 0.41546 0.01752  -0.03428 0.13265  126 GLY A O   
1683 N N   . GLU A 113 ? 0.31797 0.43072 0.29516 0.02666  -0.03006 0.18082  127 GLU A N   
1684 C CA  . GLU A 113 ? 0.35205 0.45887 0.37966 0.05050  -0.01396 0.18421  127 GLU A CA  
1685 C C   . GLU A 113 ? 0.29850 0.42602 0.33844 0.04346  -0.04392 0.17696  127 GLU A C   
1686 O O   . GLU A 113 ? 0.29979 0.42533 0.36945 0.04187  -0.04882 0.16577  127 GLU A O   
1687 C CB  . GLU A 113 ? 0.44642 0.50791 0.49487 0.07720  0.06070  0.20472  127 GLU A CB  
1688 C CG  . GLU A 113 ? 0.52776 0.54666 0.59006 0.09990  0.12263  0.23379  127 GLU A CG  
1689 C CD  . GLU A 113 ? 0.58793 0.57457 0.64912 0.11459  0.16727  0.26371  127 GLU A CD  
1690 O OE1 . GLU A 113 ? 0.60417 0.58984 0.67686 0.11685  0.17529  0.26192  127 GLU A OE1 
1691 O OE2 . GLU A 113 ? 0.61127 0.58248 0.66628 0.12616  0.17756  0.27468  127 GLU A OE2 
1698 N N   . ALA A 114 ? 0.25974 0.39449 0.30059 0.03568  -0.02208 0.15483  128 ALA A N   
1699 C CA  . ALA A 114 ? 0.21402 0.35712 0.24966 0.02565  -0.04935 0.11906  128 ALA A CA  
1700 C C   . ALA A 114 ? 0.18785 0.32235 0.24749 0.02100  -0.03055 0.07938  128 ALA A C   
1701 O O   . ALA A 114 ? 0.19471 0.32517 0.28194 0.02768  0.01984  0.09245  128 ALA A O   
1702 C CB  . ALA A 114 ? 0.23025 0.36216 0.25278 0.01117  -0.05610 0.10066  128 ALA A CB  
1708 N N   . PRO A 115 ? 0.16373 0.28408 0.21286 -0.00961 -0.05217 0.02650  129 PRO A N   
1709 C CA  . PRO A 115 ? 0.15586 0.26839 0.18877 -0.02103 -0.07527 0.02277  129 PRO A CA  
1710 C C   . PRO A 115 ? 0.12399 0.25073 0.17457 -0.01998 -0.07272 0.01775  129 PRO A C   
1711 O O   . PRO A 115 ? 0.12301 0.23885 0.20231 -0.01352 -0.06675 0.01417  129 PRO A O   
1712 C CB  . PRO A 115 ? 0.18653 0.27532 0.21316 -0.03648 -0.04913 -0.00327 129 PRO A CB  
1713 C CG  . PRO A 115 ? 0.19842 0.28503 0.25629 -0.02394 -0.01252 0.00209  129 PRO A CG  
1714 C CD  . PRO A 115 ? 0.18232 0.28188 0.25425 -0.02212 -0.00934 0.00947  129 PRO A CD  
1722 N N   . GLN A 116 ? 0.10262 0.24587 0.15862 -0.01890 -0.06029 0.01197  130 GLN A N   
1723 C CA  . GLN A 116 ? 0.11490 0.22886 0.15302 -0.01610 -0.07144 0.00736  130 GLN A CA  
1724 C C   . GLN A 116 ? 0.09382 0.21497 0.16478 -0.00957 -0.06535 -0.00020 130 GLN A C   
1725 O O   . GLN A 116 ? 0.10397 0.22824 0.14885 -0.01019 -0.06456 0.00151  130 GLN A O   
1726 C CB  . GLN A 116 ? 0.11041 0.26019 0.16270 -0.02022 -0.06359 -0.00262 130 GLN A CB  
1727 C CG  . GLN A 116 ? 0.12889 0.28652 0.16083 -0.03169 -0.04672 -0.02135 130 GLN A CG  
1728 C CD  . GLN A 116 ? 0.14099 0.30485 0.17076 -0.03175 -0.05487 0.00992  130 GLN A CD  
1729 O OE1 . GLN A 116 ? 0.12736 0.31025 0.16825 -0.03639 -0.05514 0.01466  130 GLN A OE1 
1730 N NE2 . GLN A 116 ? 0.17596 0.31847 0.18598 -0.04234 -0.07286 0.03934  130 GLN A NE2 
1739 N N   . LEU A 117 ? 0.08852 0.19335 0.15050 -0.01471 -0.06055 0.00296  131 LEU A N   
1740 C CA  . LEU A 117 ? 0.09871 0.18854 0.13665 0.00064  -0.04196 0.01403  131 LEU A CA  
1741 C C   . LEU A 117 ? 0.09072 0.18892 0.13453 0.00680  -0.05806 0.00532  131 LEU A C   
1742 O O   . LEU A 117 ? 0.07758 0.19872 0.14997 0.00101  -0.04451 -0.00025 131 LEU A O   
1743 C CB  . LEU A 117 ? 0.09455 0.18174 0.15554 -0.00022 -0.03822 0.00860  131 LEU A CB  
1744 C CG  . LEU A 117 ? 0.08764 0.18724 0.15774 0.01174  -0.04852 0.01284  131 LEU A CG  
1745 C CD1 . LEU A 117 ? 0.09530 0.19013 0.15364 0.00533  -0.05509 0.01223  131 LEU A CD1 
1746 C CD2 . LEU A 117 ? 0.09694 0.19030 0.17331 0.01524  -0.06009 0.00894  131 LEU A CD2 
1758 N N   . ARG A 118 ? 0.08795 0.17677 0.13529 -0.01418 -0.05044 0.01349  132 ARG A N   
1759 C CA  . ARG A 118 ? 0.09459 0.17326 0.14290 -0.00789 -0.04394 0.00554  132 ARG A CA  
1760 C C   . ARG A 118 ? 0.06930 0.17138 0.14706 -0.00146 -0.04993 0.00717  132 ARG A C   
1761 O O   . ARG A 118 ? 0.08718 0.19026 0.15516 -0.01582 -0.05943 0.01146  132 ARG A O   
1762 C CB  . ARG A 118 ? 0.11733 0.17351 0.14863 0.00454  -0.06092 0.01361  132 ARG A CB  
1763 C CG  . ARG A 118 ? 0.13809 0.17856 0.17527 0.00139  -0.06518 0.01284  132 ARG A CG  
1764 C CD  . ARG A 118 ? 0.17071 0.19425 0.20503 0.01676  -0.07185 0.01398  132 ARG A CD  
1765 N NE  . ARG A 118 ? 0.17290 0.21439 0.21978 0.02272  -0.11306 -0.00141 132 ARG A NE  
1766 C CZ  . ARG A 118 ? 0.15641 0.23780 0.28845 0.01821  -0.11443 -0.01111 132 ARG A CZ  
1767 N NH1 . ARG A 118 ? 0.13570 0.24489 0.29386 0.00638  -0.09301 -0.01134 132 ARG A NH1 
1768 N NH2 . ARG A 118 ? 0.15767 0.26678 0.34331 0.01158  -0.11657 -0.02491 132 ARG A NH2 
1782 N N   . ILE A 119 ? 0.07225 0.16382 0.14888 -0.00122 -0.04957 0.00155  133 ILE A N   
1783 C CA  . ILE A 119 ? 0.07177 0.16119 0.14413 0.00401  -0.03256 0.00663  133 ILE A CA  
1784 C C   . ILE A 119 ? 0.07247 0.16511 0.13938 0.00386  -0.05071 0.01009  133 ILE A C   
1785 O O   . ILE A 119 ? 0.07505 0.16645 0.14330 -0.00341 -0.05041 0.00184  133 ILE A O   
1786 C CB  . ILE A 119 ? 0.07643 0.15699 0.14832 0.00931  -0.04330 -0.00392 133 ILE A CB  
1787 C CG1 . ILE A 119 ? 0.09484 0.16091 0.17104 0.01767  -0.04058 -0.00283 133 ILE A CG1 
1788 C CG2 . ILE A 119 ? 0.10182 0.16333 0.16434 0.01687  -0.04963 0.01003  133 ILE A CG2 
1789 C CD1 . ILE A 119 ? 0.11440 0.16475 0.21293 0.02147  -0.03376 -0.00072 133 ILE A CD1 
1801 N N   . SER A 120 ? 0.07686 0.16197 0.14486 0.00395  -0.04853 -0.01015 134 SER A N   
1802 C CA  . SER A 120 ? 0.07211 0.17458 0.14792 0.00791  -0.05098 0.00125  134 SER A CA  
1803 C C   . SER A 120 ? 0.08460 0.18128 0.15091 -0.00288 -0.03555 0.01370  134 SER A C   
1804 O O   . SER A 120 ? 0.10935 0.18840 0.16061 -0.01848 -0.02444 0.00749  134 SER A O   
1805 C CB  . SER A 120 ? 0.08186 0.18962 0.16601 0.01192  -0.05895 -0.00415 134 SER A CB  
1806 O OG  . SER A 120 ? 0.09259 0.20716 0.18572 0.01731  -0.05615 -0.00783 134 SER A OG  
1812 N N   . TRP A 121 ? 0.08480 0.18718 0.13299 0.00580  -0.05040 0.00626  135 TRP A N   
1813 C CA  . TRP A 121 ? 0.09334 0.18838 0.13306 0.00441  -0.04154 0.00646  135 TRP A CA  
1814 C C   . TRP A 121 ? 0.08568 0.18471 0.14595 0.00274  -0.04080 0.00097  135 TRP A C   
1815 O O   . TRP A 121 ? 0.10201 0.17541 0.16734 0.01280  -0.03145 0.00141  135 TRP A O   
1816 C CB  . TRP A 121 ? 0.09873 0.18978 0.13939 0.01889  -0.03255 -0.00052 135 TRP A CB  
1817 C CG  . TRP A 121 ? 0.10255 0.20146 0.14541 0.01053  -0.03131 -0.01406 135 TRP A CG  
1818 C CD1 . TRP A 121 ? 0.12341 0.20943 0.14440 0.01299  -0.03184 0.00274  135 TRP A CD1 
1819 C CD2 . TRP A 121 ? 0.10279 0.20393 0.15509 0.01403  -0.03163 -0.02525 135 TRP A CD2 
1820 N NE1 . TRP A 121 ? 0.13927 0.21193 0.13769 0.01109  -0.01924 0.00121  135 TRP A NE1 
1821 C CE2 . TRP A 121 ? 0.11323 0.20691 0.15872 0.01227  -0.03762 -0.02680 135 TRP A CE2 
1822 C CE3 . TRP A 121 ? 0.12818 0.20463 0.16851 -0.00112 -0.01910 -0.02135 135 TRP A CE3 
1823 C CZ2 . TRP A 121 ? 0.12928 0.22315 0.19921 0.00996  -0.03735 -0.03260 135 TRP A CZ2 
1824 C CZ3 . TRP A 121 ? 0.14399 0.21198 0.18801 0.00430  -0.03527 -0.02481 135 TRP A CZ3 
1825 C CH2 . TRP A 121 ? 0.13733 0.21451 0.22045 0.01401  -0.02797 -0.03825 135 TRP A CH2 
1836 N N   . ILE A 122 ? 0.07967 0.19644 0.15563 0.01374  -0.03888 -0.00111 136 ILE A N   
1837 C CA  . ILE A 122 ? 0.08843 0.22061 0.19411 0.01958  -0.03966 -0.00590 136 ILE A CA  
1838 C C   . ILE A 122 ? 0.07830 0.20551 0.17398 0.01722  -0.04701 -0.00990 136 ILE A C   
1839 O O   . ILE A 122 ? 0.10340 0.21486 0.17667 0.01062  -0.03933 -0.01545 136 ILE A O   
1840 C CB  . ILE A 122 ? 0.11699 0.25664 0.22639 0.03886  -0.05980 -0.00597 136 ILE A CB  
1841 C CG1 . ILE A 122 ? 0.15143 0.28305 0.25846 0.02702  -0.07563 -0.01026 136 ILE A CG1 
1842 C CG2 . ILE A 122 ? 0.13149 0.26329 0.25619 0.03724  -0.05082 -0.00090 136 ILE A CG2 
1843 C CD1 . ILE A 122 ? 0.16318 0.29002 0.28641 0.01615  -0.08064 -0.00238 136 ILE A CD1 
1855 N N   . ARG A 123 ? 0.08040 0.20453 0.19712 0.02855  -0.03743 -0.01284 137 ARG A N   
1856 C CA  . ARG A 123 ? 0.09500 0.22515 0.20105 0.01160  -0.03020 -0.03684 137 ARG A CA  
1857 C C   . ARG A 123 ? 0.07948 0.23383 0.21952 0.00849  -0.02894 -0.02183 137 ARG A C   
1858 O O   . ARG A 123 ? 0.09450 0.23717 0.20892 -0.00288 -0.02258 -0.00741 137 ARG A O   
1859 C CB  . ARG A 123 ? 0.12512 0.23750 0.24869 0.01423  -0.01491 -0.06176 137 ARG A CB  
1860 C CG  . ARG A 123 ? 0.15415 0.25300 0.27704 0.00353  0.01729  -0.08223 137 ARG A CG  
1861 C CD  . ARG A 123 ? 0.19763 0.27368 0.30471 -0.00931 0.03569  -0.07316 137 ARG A CD  
1862 N NE  . ARG A 123 ? 0.23193 0.29270 0.29059 -0.02604 0.02568  -0.06712 137 ARG A NE  
1863 C CZ  . ARG A 123 ? 0.25942 0.30384 0.29624 -0.03548 0.05208  -0.05026 137 ARG A CZ  
1864 N NH1 . ARG A 123 ? 0.29674 0.30602 0.30971 -0.04380 0.06619  -0.04493 137 ARG A NH1 
1865 N NH2 . ARG A 123 ? 0.25447 0.30280 0.28358 -0.03231 0.02525  -0.05614 137 ARG A NH2 
1879 N N   A SER A 124 ? 0.08321 0.24286 0.23239 -0.00109 -0.05223 -0.01038 138 SER A N   
1880 N N   B SER A 124 ? 0.08547 0.24213 0.23490 0.00289  -0.03267 -0.01623 138 SER A N   
1881 C CA  A SER A 124 ? 0.12107 0.26912 0.27031 -0.01612 -0.05592 0.00970  138 SER A CA  
1882 C CA  B SER A 124 ? 0.12364 0.26535 0.27686 -0.01133 -0.03186 0.00037  138 SER A CA  
1883 C C   A SER A 124 ? 0.12934 0.26609 0.25806 -0.02052 -0.09216 0.02436  138 SER A C   
1884 C C   B SER A 124 ? 0.12867 0.26798 0.27015 -0.01672 -0.07720 0.02491  138 SER A C   
1885 O O   A SER A 124 ? 0.15020 0.26687 0.27006 -0.03181 -0.10599 0.01771  138 SER A O   
1886 O O   B SER A 124 ? 0.14864 0.27520 0.28693 -0.03194 -0.07845 0.02141  138 SER A O   
1887 C CB  A SER A 124 ? 0.15604 0.29212 0.31464 -0.01327 -0.02712 0.01587  138 SER A CB  
1888 C CB  B SER A 124 ? 0.15784 0.28110 0.31701 -0.00866 0.00789  -0.00549 138 SER A CB  
1889 O OG  A SER A 124 ? 0.16624 0.30216 0.35868 -0.01854 -0.02326 0.00735  138 SER A OG  
1890 O OG  B SER A 124 ? 0.17354 0.28379 0.34139 -0.00187 0.01654  -0.01740 138 SER A OG  
1901 N N   . LYS A 125 ? 0.12568 0.25901 0.26160 -0.00547 -0.08744 0.04043  139 LYS A N   
1902 C CA  . LYS A 125 ? 0.13308 0.25638 0.25851 -0.01855 -0.09305 0.04000  139 LYS A CA  
1903 C C   . LYS A 125 ? 0.12857 0.23316 0.23760 -0.00794 -0.07091 0.03944  139 LYS A C   
1904 O O   . LYS A 125 ? 0.16735 0.23645 0.22718 -0.00217 -0.06043 0.04176  139 LYS A O   
1905 C CB  . LYS A 125 ? 0.16736 0.29579 0.29369 -0.04089 -0.07185 0.02799  139 LYS A CB  
1906 C CG  . LYS A 125 ? 0.22967 0.32979 0.32515 -0.05496 -0.06573 0.01154  139 LYS A CG  
1907 C CD  . LYS A 125 ? 0.28819 0.35423 0.33215 -0.05946 -0.06848 0.00808  139 LYS A CD  
1908 C CE  . LYS A 125 ? 0.31555 0.37151 0.34438 -0.06819 -0.05803 0.01305  139 LYS A CE  
1909 N NZ  . LYS A 125 ? 0.34322 0.38043 0.35718 -0.07356 -0.03495 0.03004  139 LYS A NZ  
1923 N N   . SER A 126 ? 0.10392 0.22659 0.24079 -0.00742 -0.07196 0.03006  140 SER A N   
1924 C CA  A SER A 126 ? 0.10117 0.23052 0.25653 -0.01767 -0.04943 -0.00089 140 SER A CA  
1925 C CA  B SER A 126 ? 0.10511 0.23500 0.24142 -0.01619 -0.04699 0.02105  140 SER A CA  
1926 C C   . SER A 126 ? 0.10077 0.24064 0.24499 -0.01787 -0.04536 0.01658  140 SER A C   
1927 O O   . SER A 126 ? 0.13252 0.25350 0.27074 -0.01231 -0.03525 0.02742  140 SER A O   
1928 C CB  A SER A 126 ? 0.10281 0.23212 0.30382 -0.01830 -0.05214 -0.03216 140 SER A CB  
1929 C CB  B SER A 126 ? 0.11301 0.23921 0.24202 -0.02056 -0.02924 0.01976  140 SER A CB  
1930 O OG  A SER A 126 ? 0.11982 0.23364 0.35943 -0.00858 -0.02419 -0.04299 140 SER A OG  
1931 O OG  B SER A 126 ? 0.12118 0.24327 0.24231 -0.02301 -0.00650 0.02327  140 SER A OG  
1940 N N   . LEU A 127 ? 0.09120 0.25382 0.24321 -0.00920 -0.04236 0.00690  141 LEU A N   
1941 C CA  . LEU A 127 ? 0.10727 0.28232 0.24668 0.01397  -0.03453 -0.00919 141 LEU A CA  
1942 C C   . LEU A 127 ? 0.13521 0.28334 0.26250 0.01040  -0.01874 -0.03096 141 LEU A C   
1943 O O   . LEU A 127 ? 0.16122 0.26622 0.26663 0.01103  -0.01922 -0.02171 141 LEU A O   
1944 C CB  . LEU A 127 ? 0.11610 0.30590 0.26289 0.03055  -0.02304 -0.00364 141 LEU A CB  
1945 C CG  . LEU A 127 ? 0.11910 0.32332 0.25477 0.02079  -0.04679 0.00177  141 LEU A CG  
1946 C CD1 . LEU A 127 ? 0.13321 0.33704 0.26223 0.02007  -0.06467 -0.00288 141 LEU A CD1 
1947 C CD2 . LEU A 127 ? 0.13157 0.33161 0.26404 0.00200  -0.04047 -0.00257 141 LEU A CD2 
1959 N N   . ASP A 128 ? 0.17124 0.30764 0.28058 0.00015  -0.01557 -0.04241 142 ASP A N   
1960 C CA  . ASP A 128 ? 0.21203 0.32466 0.35121 -0.00406 0.00002  -0.05542 142 ASP A CA  
1961 C C   . ASP A 128 ? 0.19701 0.31479 0.32926 -0.02560 -0.03010 -0.06999 142 ASP A C   
1962 O O   . ASP A 128 ? 0.23631 0.31036 0.35196 -0.02664 -0.00682 -0.08298 142 ASP A O   
1963 C CB  . ASP A 128 ? 0.28549 0.35265 0.46769 0.01066  0.06852  -0.04665 142 ASP A CB  
1964 C CG  . ASP A 128 ? 0.37922 0.38661 0.57808 0.02395  0.11041  -0.01757 142 ASP A CG  
1965 O OD1 . ASP A 128 ? 0.40509 0.39948 0.60745 0.01877  0.11405  -0.01178 142 ASP A OD1 
1966 O OD2 . ASP A 128 ? 0.43433 0.40428 0.63225 0.02801  0.12988  -0.00688 142 ASP A OD2 
1971 N N   . GLY A 129 ? 0.15843 0.30702 0.30204 -0.03269 -0.04665 -0.06926 143 GLY A N   
1972 C CA  . GLY A 129 ? 0.14847 0.29375 0.33608 -0.03311 -0.02316 -0.06285 143 GLY A CA  
1973 C C   . GLY A 129 ? 0.15288 0.27250 0.32652 -0.04851 -0.01331 -0.06864 143 GLY A C   
1974 O O   . GLY A 129 ? 0.16824 0.29011 0.33789 -0.05626 0.00132  -0.07951 143 GLY A O   
1978 N N   . VAL A 130 ? 0.17085 0.24356 0.29323 -0.04399 -0.01950 -0.04554 144 VAL A N   
1979 C CA  . VAL A 130 ? 0.20194 0.21363 0.29169 -0.03270 -0.01343 -0.02233 144 VAL A CA  
1980 C C   . VAL A 130 ? 0.15382 0.19408 0.24101 -0.01869 -0.02841 -0.01119 144 VAL A C   
1981 O O   . VAL A 130 ? 0.15730 0.18786 0.25409 -0.00959 -0.00657 -0.00926 144 VAL A O   
1982 C CB  . VAL A 130 ? 0.27540 0.21424 0.34930 -0.03130 0.01023  -0.01777 144 VAL A CB  
1983 C CG1 . VAL A 130 ? 0.30319 0.22212 0.37123 -0.02443 0.01678  -0.00396 144 VAL A CG1 
1984 C CG2 . VAL A 130 ? 0.30452 0.21695 0.39028 -0.03440 0.02073  -0.02764 144 VAL A CG2 
1994 N N   . ALA A 131 ? 0.13385 0.19994 0.24316 -0.01153 -0.04032 -0.00632 145 ALA A N   
1995 C CA  . ALA A 131 ? 0.12894 0.20732 0.24440 -0.00613 -0.04403 0.00079  145 ALA A CA  
1996 C C   . ALA A 131 ? 0.12825 0.20984 0.22277 -0.00577 -0.05055 0.02401  145 ALA A C   
1997 O O   . ALA A 131 ? 0.16444 0.23237 0.26240 -0.00832 -0.04896 0.05853  145 ALA A O   
1998 C CB  . ALA A 131 ? 0.14475 0.21242 0.25911 0.00497  -0.02941 -0.02000 145 ALA A CB  
2004 N N   . TYR A 132 ? 0.13168 0.20164 0.24348 0.00362  -0.05642 0.01567  146 TYR A N   
2005 C CA  . TYR A 132 ? 0.12514 0.21291 0.25647 0.00365  -0.05563 0.01988  146 TYR A CA  
2006 C C   . TYR A 132 ? 0.12262 0.22211 0.22880 -0.00042 -0.05907 0.02161  146 TYR A C   
2007 O O   . TYR A 132 ? 0.14064 0.22002 0.24025 -0.01594 -0.07156 0.02941  146 TYR A O   
2008 C CB  . TYR A 132 ? 0.15244 0.22483 0.28684 0.00631  -0.05056 0.01467  146 TYR A CB  
2009 C CG  . TYR A 132 ? 0.18365 0.23613 0.29962 0.02576  -0.05969 0.00940  146 TYR A CG  
2010 C CD1 . TYR A 132 ? 0.23985 0.24096 0.32408 0.02663  -0.05118 -0.00362 146 TYR A CD1 
2011 C CD2 . TYR A 132 ? 0.19218 0.24482 0.31161 0.02635  -0.03814 -0.00255 146 TYR A CD2 
2012 C CE1 . TYR A 132 ? 0.26959 0.23749 0.34175 0.03577  -0.05025 -0.00864 146 TYR A CE1 
2013 C CE2 . TYR A 132 ? 0.23590 0.25180 0.33820 0.03343  -0.03059 -0.01274 146 TYR A CE2 
2014 C CZ  . TYR A 132 ? 0.27294 0.24562 0.34410 0.03477  -0.04924 -0.02503 146 TYR A CZ  
2015 O OH  . TYR A 132 ? 0.32319 0.25421 0.38202 0.02511  -0.03765 -0.04397 146 TYR A OH  
2025 N N   . GLU A 133 ? 0.13457 0.24915 0.22836 0.01297  -0.06385 0.02053  147 GLU A N   
2026 C CA  . GLU A 133 ? 0.12694 0.26860 0.24551 0.01049  -0.04627 0.00229  147 GLU A CA  
2027 C C   . GLU A 133 ? 0.12393 0.26031 0.21654 0.00910  -0.03665 0.00729  147 GLU A C   
2028 O O   . GLU A 133 ? 0.13407 0.25446 0.21045 0.01512  -0.04076 0.02082  147 GLU A O   
2029 C CB  . GLU A 133 ? 0.11398 0.30314 0.34727 0.02064  -0.06254 -0.01566 147 GLU A CB  
2030 C CG  . GLU A 133 ? 0.16217 0.33601 0.49464 0.01573  -0.02502 -0.00918 147 GLU A CG  
2031 C CD  . GLU A 133 ? 0.22321 0.36603 0.61101 0.00989  -0.00276 0.01269  147 GLU A CD  
2032 O OE1 . GLU A 133 ? 0.24715 0.38067 0.65414 0.00946  0.00682  0.02287  147 GLU A OE1 
2033 O OE2 . GLU A 133 ? 0.25159 0.37682 0.66108 0.02017  0.02431  0.01727  147 GLU A OE2 
2040 N N   . ASP A 134 ? 0.09402 0.26001 0.20065 0.01214  -0.02029 0.00500  148 ASP A N   
2041 C CA  . ASP A 134 ? 0.10988 0.26414 0.16205 0.01223  -0.02765 -0.00129 148 ASP A CA  
2042 C C   . ASP A 134 ? 0.10353 0.24856 0.16277 0.01920  -0.02712 0.00726  148 ASP A C   
2043 O O   . ASP A 134 ? 0.12089 0.25609 0.16871 0.01485  -0.03376 0.01220  148 ASP A O   
2044 C CB  . ASP A 134 ? 0.11394 0.28781 0.16514 0.01371  -0.01980 0.00192  148 ASP A CB  
2045 C CG  . ASP A 134 ? 0.13094 0.30529 0.15695 0.00642  0.00114  0.01122  148 ASP A CG  
2046 O OD1 . ASP A 134 ? 0.12526 0.31573 0.16326 0.00354  -0.02764 -0.00099 148 ASP A OD1 
2047 O OD2 . ASP A 134 ? 0.15919 0.31836 0.16204 0.00115  -0.01477 0.01781  148 ASP A OD2 
2052 N N   . PHE A 135 ? 0.09386 0.22629 0.15566 0.00697  -0.02802 0.01568  149 PHE A N   
2053 C CA  . PHE A 135 ? 0.08767 0.21309 0.14881 -0.00278 -0.02984 0.00860  149 PHE A CA  
2054 C C   . PHE A 135 ? 0.08845 0.19272 0.14500 0.00288  -0.04049 0.01757  149 PHE A C   
2055 O O   . PHE A 135 ? 0.09748 0.18418 0.16780 0.01060  -0.03249 0.01983  149 PHE A O   
2056 C CB  . PHE A 135 ? 0.08920 0.22158 0.15677 -0.00070 -0.03014 -0.00014 149 PHE A CB  
2057 C CG  . PHE A 135 ? 0.09326 0.24014 0.17317 0.00428  -0.03720 0.00557  149 PHE A CG  
2058 C CD1 . PHE A 135 ? 0.08565 0.26547 0.19349 0.00949  -0.03458 0.00146  149 PHE A CD1 
2059 C CD2 . PHE A 135 ? 0.10008 0.25230 0.18052 -0.00088 -0.03556 0.01750  149 PHE A CD2 
2060 C CE1 . PHE A 135 ? 0.10243 0.27337 0.20757 0.01141  -0.03470 -0.00006 149 PHE A CE1 
2061 C CE2 . PHE A 135 ? 0.09629 0.26114 0.19461 -0.00481 -0.04712 0.00970  149 PHE A CE2 
2062 C CZ  . PHE A 135 ? 0.10311 0.26440 0.20307 -0.00359 -0.03799 0.00339  149 PHE A CZ  
2072 N N   . ILE A 136 ? 0.09309 0.17681 0.14172 0.00914  -0.03300 0.01847  150 ILE A N   
2073 C CA  . ILE A 136 ? 0.08704 0.19168 0.14194 0.00659  -0.04913 0.01677  150 ILE A CA  
2074 C C   . ILE A 136 ? 0.07666 0.17980 0.16138 -0.00175 -0.03989 0.02009  150 ILE A C   
2075 O O   . ILE A 136 ? 0.10551 0.17501 0.16173 -0.00022 -0.04364 0.01630  150 ILE A O   
2076 C CB  . ILE A 136 ? 0.09418 0.20608 0.14910 0.01413  -0.06213 0.00594  150 ILE A CB  
2077 C CG1 . ILE A 136 ? 0.10817 0.21462 0.18125 0.02609  -0.05856 0.00513  150 ILE A CG1 
2078 C CG2 . ILE A 136 ? 0.09528 0.22879 0.17068 0.02352  -0.03422 -0.00039 150 ILE A CG2 
2079 C CD1 . ILE A 136 ? 0.10431 0.21747 0.17393 0.02054  -0.05879 -0.00678 150 ILE A CD1 
2091 N N   . MET A 137 ? 0.08653 0.17799 0.15053 -0.01233 -0.04525 0.00768  151 MET A N   
2092 C CA  . MET A 137 ? 0.07999 0.19645 0.15207 -0.01359 -0.05351 0.00529  151 MET A CA  
2093 C C   . MET A 137 ? 0.09539 0.17798 0.15148 -0.00771 -0.04163 -0.00088 151 MET A C   
2094 O O   . MET A 137 ? 0.09812 0.18528 0.16854 -0.01728 -0.03258 -0.01600 151 MET A O   
2095 C CB  . MET A 137 ? 0.07793 0.23826 0.18000 0.00829  -0.04578 0.00406  151 MET A CB  
2096 C CG  . MET A 137 ? 0.09953 0.25498 0.20543 0.01657  -0.06838 0.00446  151 MET A CG  
2097 S SD  . MET A 137 ? 0.09893 0.29994 0.21596 0.03050  -0.04839 0.01403  151 MET A SD  
2098 C CE  . MET A 137 ? 0.13458 0.30699 0.29743 0.05136  0.00026  0.05186  151 MET A CE  
2108 N N   . SER A 138 ? 0.09565 0.15075 0.14911 -0.01039 -0.04687 0.01444  152 SER A N   
2109 C CA  . SER A 138 ? 0.07399 0.16852 0.16295 -0.00144 -0.05428 0.00912  152 SER A CA  
2110 C C   . SER A 138 ? 0.06880 0.17020 0.14573 0.00060  -0.05128 0.00098  152 SER A C   
2111 O O   . SER A 138 ? 0.08064 0.18031 0.16302 0.00401  -0.05774 0.01373  152 SER A O   
2112 C CB  . SER A 138 ? 0.09864 0.17858 0.18137 0.00967  -0.03951 0.01847  152 SER A CB  
2113 O OG  . SER A 138 ? 0.12807 0.19374 0.18147 0.00221  -0.03912 0.02289  152 SER A OG  
2119 N N   . THR A 139 ? 0.07502 0.16544 0.13654 -0.00202 -0.05321 0.00986  153 THR A N   
2120 C CA  . THR A 139 ? 0.09533 0.18472 0.15754 0.00306  -0.06134 0.01941  153 THR A CA  
2121 C C   . THR A 139 ? 0.09117 0.16519 0.15186 0.00874  -0.06331 0.01681  153 THR A C   
2122 O O   . THR A 139 ? 0.08809 0.18640 0.15340 -0.00155 -0.06145 0.00401  153 THR A O   
2123 C CB  . THR A 139 ? 0.10568 0.20569 0.16642 0.01902  -0.06244 0.01721  153 THR A CB  
2124 O OG1 . THR A 139 ? 0.11456 0.19643 0.18419 0.02374  -0.05409 0.00463  153 THR A OG1 
2125 C CG2 . THR A 139 ? 0.11976 0.22396 0.18289 0.02479  -0.06479 0.03367  153 THR A CG2 
2133 N N   . VAL A 140 ? 0.08262 0.17212 0.15374 -0.00391 -0.05824 0.00735  154 VAL A N   
2134 C CA  . VAL A 140 ? 0.08689 0.18551 0.14650 -0.00279 -0.05540 -0.00113 154 VAL A CA  
2135 C C   . VAL A 140 ? 0.09553 0.19971 0.15467 -0.00240 -0.06873 -0.00151 154 VAL A C   
2136 O O   . VAL A 140 ? 0.10300 0.21290 0.17189 -0.00705 -0.07057 0.01887  154 VAL A O   
2137 C CB  . VAL A 140 ? 0.10425 0.18965 0.16562 -0.00585 -0.06380 -0.00034 154 VAL A CB  
2138 C CG1 . VAL A 140 ? 0.12643 0.19626 0.17271 -0.00207 -0.05531 0.00220  154 VAL A CG1 
2139 C CG2 . VAL A 140 ? 0.12222 0.19707 0.17851 0.00924  -0.07110 0.00181  154 VAL A CG2 
2149 N N   . ARG A 141 ? 0.09954 0.19478 0.14936 -0.00210 -0.05989 0.02012  155 ARG A N   
2150 C CA  . ARG A 141 ? 0.12037 0.20640 0.16236 0.00158  -0.07898 0.01358  155 ARG A CA  
2151 C C   . ARG A 141 ? 0.11198 0.21671 0.16173 0.00062  -0.06527 0.03275  155 ARG A C   
2152 O O   . ARG A 141 ? 0.13691 0.22946 0.16402 -0.00607 -0.06031 0.01225  155 ARG A O   
2153 C CB  . ARG A 141 ? 0.13216 0.21585 0.17326 -0.00220 -0.07854 0.01933  155 ARG A CB  
2154 C CG  . ARG A 141 ? 0.15161 0.21521 0.18826 -0.00071 -0.08260 0.01080  155 ARG A CG  
2155 C CD  . ARG A 141 ? 0.16697 0.21336 0.20260 -0.00845 -0.08496 0.01147  155 ARG A CD  
2156 N NE  . ARG A 141 ? 0.17712 0.22912 0.20773 -0.00401 -0.11370 0.01279  155 ARG A NE  
2157 C CZ  . ARG A 141 ? 0.21158 0.23584 0.21244 0.00669  -0.12482 0.02072  155 ARG A CZ  
2158 N NH1 . ARG A 141 ? 0.21873 0.23264 0.22435 0.00741  -0.13056 0.01961  155 ARG A NH1 
2159 N NH2 . ARG A 141 ? 0.23591 0.24268 0.25475 0.03430  -0.10999 0.03642  155 ARG A NH2 
2173 N N   . ILE A 142 ? 0.13465 0.23239 0.15075 -0.01132 -0.07263 0.02284  156 ILE A N   
2174 C CA  . ILE A 142 ? 0.17346 0.24351 0.16303 -0.02231 -0.07003 0.01544  156 ILE A CA  
2175 C C   . ILE A 142 ? 0.19274 0.26675 0.17327 -0.04136 -0.09812 0.01797  156 ILE A C   
2176 O O   . ILE A 142 ? 0.21658 0.28547 0.16771 -0.05701 -0.09459 0.01449  156 ILE A O   
2177 C CB  . ILE A 142 ? 0.19860 0.24774 0.18991 -0.02872 -0.07219 0.02537  156 ILE A CB  
2178 C CG1 . ILE A 142 ? 0.20011 0.25508 0.22618 -0.04629 -0.07968 0.03219  156 ILE A CG1 
2179 C CG2 . ILE A 142 ? 0.21172 0.24328 0.20735 -0.01942 -0.07733 0.01835  156 ILE A CG2 
2180 C CD1 . ILE A 142 ? 0.22283 0.27422 0.26657 -0.06465 -0.05588 0.03513  156 ILE A CD1 
2192 N N   . GLY A 143 ? 0.19731 0.27192 0.17764 -0.03435 -0.09683 0.03065  157 GLY A N   
2193 C CA  . GLY A 143 ? 0.21276 0.27803 0.17230 -0.04206 -0.10355 0.03987  157 GLY A CA  
2194 C C   . GLY A 143 ? 0.21782 0.28370 0.18835 -0.03266 -0.11254 0.04211  157 GLY A C   
2195 O O   . GLY A 143 ? 0.21098 0.26976 0.19134 -0.01308 -0.10844 0.03283  157 GLY A O   
2199 N N   . THR A 144 ? 0.23264 0.29502 0.19767 -0.04628 -0.11885 0.03932  158 THR A N   
2200 C CA  . THR A 144 ? 0.25213 0.30942 0.23060 -0.05648 -0.13371 0.05487  158 THR A CA  
2201 C C   . THR A 144 ? 0.26455 0.31689 0.27367 -0.03572 -0.15218 0.06520  158 THR A C   
2202 O O   . THR A 144 ? 0.27042 0.31720 0.32832 -0.04178 -0.15491 0.05574  158 THR A O   
2203 C CB  . THR A 144 ? 0.25565 0.31707 0.23293 -0.05977 -0.13570 0.04649  158 THR A CB  
2204 O OG1 . THR A 144 ? 0.27003 0.33783 0.24052 -0.07839 -0.13771 0.04196  158 THR A OG1 
2205 C CG2 . THR A 144 ? 0.25288 0.32820 0.24453 -0.06483 -0.13624 0.04180  158 THR A CG2 
2213 N N   . GLY A 145 ? 0.26970 0.33122 0.28540 -0.01402 -0.15588 0.06639  159 GLY A N   
2214 C CA  . GLY A 145 ? 0.27312 0.35073 0.31885 0.00379  -0.16030 0.07743  159 GLY A CA  
2215 C C   . GLY A 145 ? 0.29059 0.36812 0.35155 0.03335  -0.17214 0.06819  159 GLY A C   
2216 O O   . GLY A 145 ? 0.30109 0.37014 0.32934 0.04120  -0.16880 0.06712  159 GLY A O   
2220 N N   . ASP A 146 ? 0.30910 0.38334 0.41001 0.04863  -0.18762 0.06638  160 ASP A N   
2221 C CA  . ASP A 146 ? 0.34781 0.40092 0.49571 0.06733  -0.13710 0.06832  160 ASP A CA  
2222 C C   . ASP A 146 ? 0.31557 0.40913 0.46978 0.08714  -0.15979 0.07498  160 ASP A C   
2223 O O   . ASP A 146 ? 0.32190 0.41083 0.49336 0.08463  -0.14054 0.06621  160 ASP A O   
2224 C CB  . ASP A 146 ? 0.42832 0.41828 0.62208 0.05605  -0.04056 0.04473  160 ASP A CB  
2225 C CG  . ASP A 146 ? 0.49721 0.43537 0.72727 0.05264  0.03224  0.02958  160 ASP A CG  
2226 O OD1 . ASP A 146 ? 0.52540 0.44283 0.76924 0.04811  0.06827  0.01602  160 ASP A OD1 
2227 O OD2 . ASP A 146 ? 0.52661 0.44350 0.76688 0.04746  0.05689  0.02356  160 ASP A OD2 
2232 N N   . SER A 147 ? 0.28041 0.41640 0.43209 0.08721  -0.16102 0.07035  161 SER A N   
2233 C CA  . SER A 147 ? 0.25834 0.42752 0.38873 0.09024  -0.14497 0.07013  161 SER A CA  
2234 C C   . SER A 147 ? 0.23312 0.43115 0.34390 0.08711  -0.12103 0.06537  161 SER A C   
2235 O O   . SER A 147 ? 0.22857 0.41853 0.31511 0.09031  -0.10661 0.06664  161 SER A O   
2236 C CB  . SER A 147 ? 0.26146 0.43915 0.36698 0.07951  -0.15485 0.05936  161 SER A CB  
2237 O OG  . SER A 147 ? 0.27414 0.45058 0.39689 0.05316  -0.12114 0.05302  161 SER A OG  
2243 N N   . SER A 148 ? 0.21560 0.43488 0.33185 0.08106  -0.10781 0.06463  162 SER A N   
2244 C CA  A SER A 148 ? 0.20714 0.44132 0.33456 0.06844  -0.09265 0.06879  162 SER A CA  
2245 C CA  B SER A 148 ? 0.21042 0.43896 0.32773 0.07289  -0.09298 0.06874  162 SER A CA  
2246 C C   . SER A 148 ? 0.18860 0.43088 0.33437 0.05377  -0.10708 0.05662  162 SER A C   
2247 O O   . SER A 148 ? 0.17687 0.42604 0.32344 0.04292  -0.09482 0.06715  162 SER A O   
2248 C CB  A SER A 148 ? 0.22527 0.44504 0.36871 0.06142  -0.06149 0.06591  162 SER A CB  
2249 C CB  B SER A 148 ? 0.23514 0.43804 0.34568 0.07489  -0.06365 0.06664  162 SER A CB  
2250 O OG  A SER A 148 ? 0.23832 0.45055 0.39485 0.05687  -0.04110 0.06129  162 SER A OG  
2251 O OG  B SER A 148 ? 0.25554 0.43920 0.35654 0.07939  -0.04494 0.06290  162 SER A OG  
2260 N N   . ASP A 149 ? 0.19748 0.42287 0.34622 0.04628  -0.13576 0.02047  163 ASP A N   
2261 C CA  . ASP A 149 ? 0.20961 0.41843 0.35080 0.02386  -0.15035 0.00781  163 ASP A CA  
2262 C C   . ASP A 149 ? 0.19226 0.38908 0.30937 0.01185  -0.13757 0.01061  163 ASP A C   
2263 O O   . ASP A 149 ? 0.18052 0.38003 0.35461 -0.00415 -0.13449 0.00438  163 ASP A O   
2264 C CB  . ASP A 149 ? 0.28274 0.44187 0.42586 0.03589  -0.11277 -0.03232 163 ASP A CB  
2265 C CG  . ASP A 149 ? 0.35786 0.46809 0.47578 0.04261  -0.07684 -0.04617 163 ASP A CG  
2266 O OD1 . ASP A 149 ? 0.37607 0.47908 0.46996 0.04474  -0.09262 -0.04188 163 ASP A OD1 
2267 O OD2 . ASP A 149 ? 0.40160 0.48308 0.53600 0.04528  -0.02810 -0.04988 163 ASP A OD2 
2272 N N   . ASN A 150 ? 0.18745 0.34312 0.26032 0.01604  -0.11981 0.04046  164 ASN A N   
2273 C CA  . ASN A 150 ? 0.17660 0.31543 0.23973 0.01916  -0.10009 0.06359  164 ASN A CA  
2274 C C   . ASN A 150 ? 0.14694 0.29813 0.20813 0.00945  -0.08618 0.04527  164 ASN A C   
2275 O O   . ASN A 150 ? 0.13703 0.30328 0.18283 0.00901  -0.07150 0.04347  164 ASN A O   
2276 C CB  . ASN A 150 ? 0.18419 0.32683 0.25201 0.01698  -0.08957 0.09478  164 ASN A CB  
2277 C CG  . ASN A 150 ? 0.19375 0.34414 0.26525 0.01128  -0.08447 0.10684  164 ASN A CG  
2278 O OD1 . ASN A 150 ? 0.20445 0.35134 0.24692 -0.00809 -0.07747 0.09608  164 ASN A OD1 
2279 N ND2 . ASN A 150 ? 0.20855 0.34868 0.28660 0.01983  -0.09655 0.10471  164 ASN A ND2 
2286 N N   . PHE A 151 ? 0.12355 0.28080 0.20595 0.00693  -0.07378 0.04292  165 PHE A N   
2287 C CA  . PHE A 151 ? 0.11952 0.27864 0.20542 0.00745  -0.07019 0.04454  165 PHE A CA  
2288 C C   . PHE A 151 ? 0.11256 0.27790 0.20864 -0.00325 -0.06810 0.04060  165 PHE A C   
2289 O O   . PHE A 151 ? 0.12839 0.30458 0.23601 -0.00674 -0.07757 0.05300  165 PHE A O   
2290 C CB  . PHE A 151 ? 0.13986 0.28548 0.21095 0.01564  -0.07202 0.04490  165 PHE A CB  
2291 C CG  . PHE A 151 ? 0.15591 0.27557 0.21893 0.02935  -0.09754 0.03539  165 PHE A CG  
2292 C CD1 . PHE A 151 ? 0.16534 0.27251 0.22994 0.03519  -0.09901 0.03116  165 PHE A CD1 
2293 C CD2 . PHE A 151 ? 0.19104 0.28226 0.25544 0.03561  -0.08837 0.04214  165 PHE A CD2 
2294 C CE1 . PHE A 151 ? 0.19654 0.27952 0.26348 0.04059  -0.07567 0.02764  165 PHE A CE1 
2295 C CE2 . PHE A 151 ? 0.22383 0.28724 0.27310 0.04647  -0.07143 0.04743  165 PHE A CE2 
2296 C CZ  . PHE A 151 ? 0.22964 0.28535 0.27658 0.04181  -0.05215 0.03447  165 PHE A CZ  
2306 N N   . VAL A 152 ? 0.10241 0.25569 0.18566 -0.00574 -0.06027 0.03844  166 VAL A N   
2307 C CA  . VAL A 152 ? 0.09490 0.23861 0.16962 -0.02255 -0.05690 0.01813  166 VAL A CA  
2308 C C   . VAL A 152 ? 0.09797 0.22141 0.16413 -0.01711 -0.06128 0.02700  166 VAL A C   
2309 O O   . VAL A 152 ? 0.09404 0.21314 0.17054 -0.01615 -0.06148 0.02443  166 VAL A O   
2310 C CB  . VAL A 152 ? 0.11922 0.24833 0.18973 -0.02482 -0.06785 0.00190  166 VAL A CB  
2311 C CG1 . VAL A 152 ? 0.13544 0.24668 0.20499 -0.02478 -0.06751 -0.00069 166 VAL A CG1 
2312 C CG2 . VAL A 152 ? 0.15726 0.26084 0.19872 -0.02759 -0.06672 -0.00340 166 VAL A CG2 
2322 N N   . LYS A 153 ? 0.10025 0.22860 0.17966 -0.01526 -0.06514 0.02660  167 LYS A N   
2323 C CA  A LYS A 153 ? 0.10586 0.23098 0.19002 -0.01042 -0.07180 0.02464  167 LYS A CA  
2324 C CA  B LYS A 153 ? 0.10379 0.23453 0.19270 -0.01486 -0.06681 0.03622  167 LYS A CA  
2325 C C   . LYS A 153 ? 0.09736 0.23414 0.20248 -0.02596 -0.06294 0.02404  167 LYS A C   
2326 O O   . LYS A 153 ? 0.12010 0.26899 0.21174 -0.04829 -0.06914 0.03506  167 LYS A O   
2327 C CB  A LYS A 153 ? 0.11908 0.24552 0.23034 0.00783  -0.06149 0.02953  167 LYS A CB  
2328 C CB  B LYS A 153 ? 0.12948 0.23600 0.22950 0.00177  -0.03954 0.04604  167 LYS A CB  
2329 C CG  A LYS A 153 ? 0.14432 0.25464 0.28982 0.03437  -0.05983 0.02933  167 LYS A CG  
2330 C CG  B LYS A 153 ? 0.16016 0.24042 0.28721 0.02418  -0.02619 0.05470  167 LYS A CG  
2331 C CD  A LYS A 153 ? 0.17179 0.26926 0.34959 0.05618  -0.04490 0.02411  167 LYS A CD  
2332 C CD  B LYS A 153 ? 0.19362 0.25019 0.34015 0.04315  -0.00660 0.05279  167 LYS A CD  
2333 C CE  A LYS A 153 ? 0.18023 0.28001 0.38149 0.06564  -0.03633 0.01648  167 LYS A CE  
2334 C CE  B LYS A 153 ? 0.22392 0.25635 0.37085 0.05553  0.02080  0.04865  167 LYS A CE  
2335 N NZ  A LYS A 153 ? 0.16636 0.27986 0.37608 0.07312  -0.05596 0.01990  167 LYS A NZ  
2336 N NZ  B LYS A 153 ? 0.23404 0.25238 0.38158 0.05969  0.02638  0.05695  167 LYS A NZ  
2361 N N   . THR A 154 ? 0.09828 0.21782 0.17037 -0.02712 -0.06245 0.01762  168 THR A N   
2362 C CA  . THR A 154 ? 0.12215 0.20939 0.19024 -0.03196 -0.05437 0.02511  168 THR A CA  
2363 C C   . THR A 154 ? 0.10640 0.20111 0.18249 -0.01880 -0.06499 0.03006  168 THR A C   
2364 O O   . THR A 154 ? 0.10111 0.19893 0.17793 -0.02709 -0.05882 0.02760  168 THR A O   
2365 C CB  . THR A 154 ? 0.15908 0.20867 0.19674 -0.02843 -0.05388 0.01281  168 THR A CB  
2366 O OG1 . THR A 154 ? 0.18179 0.21632 0.21125 -0.01932 -0.03960 0.00475  168 THR A OG1 
2367 C CG2 . THR A 154 ? 0.17451 0.21563 0.21250 -0.03254 -0.05816 0.01162  168 THR A CG2 
2375 N N   . HIS A 155 ? 0.11093 0.19726 0.19232 -0.01881 -0.05570 0.02996  169 HIS A N   
2376 C CA  . HIS A 155 ? 0.11464 0.19800 0.18449 -0.00113 -0.05685 0.03502  169 HIS A CA  
2377 C C   . HIS A 155 ? 0.11694 0.18704 0.19436 0.01289  -0.05676 0.02340  169 HIS A C   
2378 O O   . HIS A 155 ? 0.14879 0.19009 0.26857 0.00739  -0.07294 0.02021  169 HIS A O   
2379 C CB  . HIS A 155 ? 0.13929 0.22013 0.19608 -0.00472 -0.03267 0.03392  169 HIS A CB  
2380 C CG  . HIS A 155 ? 0.16929 0.23456 0.19177 -0.00945 -0.04151 0.03963  169 HIS A CG  
2381 N ND1 . HIS A 155 ? 0.22400 0.25809 0.20863 0.00093  -0.03552 0.05048  169 HIS A ND1 
2382 C CD2 . HIS A 155 ? 0.21910 0.25073 0.22941 -0.01385 -0.03717 0.03364  169 HIS A CD2 
2383 C CE1 . HIS A 155 ? 0.22143 0.26967 0.19900 -0.00780 -0.05328 0.06058  169 HIS A CE1 
2384 N NE2 . HIS A 155 ? 0.22378 0.26502 0.21397 -0.03276 -0.02866 0.02657  169 HIS A NE2 
2392 N N   . LEU A 156 ? 0.09570 0.17714 0.19492 0.00939  -0.05295 0.02904  170 LEU A N   
2393 C CA  . LEU A 156 ? 0.11516 0.18333 0.18414 0.01373  -0.05387 0.00635  170 LEU A CA  
2394 C C   . LEU A 156 ? 0.13708 0.18358 0.19683 0.02529  -0.05651 0.01737  170 LEU A C   
2395 O O   . LEU A 156 ? 0.20108 0.19513 0.20513 0.03103  -0.06273 0.02497  170 LEU A O   
2396 C CB  . LEU A 156 ? 0.10723 0.18874 0.17982 0.02890  -0.05148 0.01170  170 LEU A CB  
2397 C CG  . LEU A 156 ? 0.12669 0.18447 0.17573 0.02606  -0.05054 0.01465  170 LEU A CG  
2398 C CD1 . LEU A 156 ? 0.11862 0.19855 0.19634 0.02136  -0.05649 0.00550  170 LEU A CD1 
2399 C CD2 . LEU A 156 ? 0.19850 0.19595 0.17983 0.01595  -0.02360 0.02197  170 LEU A CD2 
2411 N N   . ALA A 157 ? 0.11988 0.18407 0.17957 0.01400  -0.04493 0.01702  171 ALA A N   
2412 C CA  . ALA A 157 ? 0.11375 0.20619 0.16640 -0.00503 -0.05520 0.02515  171 ALA A CA  
2413 C C   . ALA A 157 ? 0.11654 0.20952 0.16965 -0.01596 -0.03699 0.01942  171 ALA A C   
2414 O O   . ALA A 157 ? 0.17148 0.20709 0.20117 -0.00662 -0.00639 0.03043  171 ALA A O   
2415 C CB  . ALA A 157 ? 0.12707 0.23098 0.19375 0.00645  -0.06265 0.02029  171 ALA A CB  
2421 N N   . ASP A 158 ? 0.12721 0.21925 0.16703 -0.02498 -0.03414 0.01006  172 ASP A N   
2422 C CA  . ASP A 158 ? 0.12439 0.24779 0.17615 -0.01039 -0.02925 0.02115  172 ASP A CA  
2423 C C   . ASP A 158 ? 0.11464 0.22989 0.17274 0.00203  -0.04530 0.02118  172 ASP A C   
2424 O O   . ASP A 158 ? 0.13538 0.22589 0.19153 -0.01140 -0.05501 0.01866  172 ASP A O   
2425 C CB  . ASP A 158 ? 0.15250 0.30155 0.20257 -0.02281 -0.00252 0.01370  172 ASP A CB  
2426 C CG  . ASP A 158 ? 0.18341 0.35086 0.26143 -0.03755 0.00321  0.02171  172 ASP A CG  
2427 O OD1 . ASP A 158 ? 0.18597 0.37298 0.25282 -0.04214 -0.01291 -0.00412 172 ASP A OD1 
2428 O OD2 . ASP A 158 ? 0.23399 0.36999 0.35064 -0.04969 0.03593  0.02097  172 ASP A OD2 
2433 N N   . ARG A 159 ? 0.11747 0.22502 0.17955 0.01021  -0.04305 0.01942  173 ARG A N   
2434 C CA  . ARG A 159 ? 0.12504 0.22597 0.15709 0.01002  -0.04357 0.01567  173 ARG A CA  
2435 C C   . ARG A 159 ? 0.14084 0.24113 0.15900 -0.00245 -0.04047 0.00508  173 ARG A C   
2436 O O   . ARG A 159 ? 0.15925 0.27154 0.16585 -0.00555 -0.02606 0.02964  173 ARG A O   
2437 C CB  . ARG A 159 ? 0.11846 0.22678 0.16545 0.00792  -0.04792 0.01480  173 ARG A CB  
2438 C CG  . ARG A 159 ? 0.11055 0.24141 0.17084 0.00226  -0.03726 0.01493  173 ARG A CG  
2439 C CD  . ARG A 159 ? 0.11664 0.25250 0.17910 0.00626  -0.03546 0.00468  173 ARG A CD  
2440 N NE  . ARG A 159 ? 0.13566 0.26558 0.18969 0.00641  -0.03638 -0.00060 173 ARG A NE  
2441 C CZ  . ARG A 159 ? 0.13913 0.29136 0.20363 -0.00401 -0.00723 0.00280  173 ARG A CZ  
2442 N NH1 . ARG A 159 ? 0.13556 0.30163 0.19156 0.00750  -0.02585 0.01794  173 ARG A NH1 
2443 N NH2 . ARG A 159 ? 0.16013 0.31338 0.24116 -0.00278 0.01911  0.00002  173 ARG A NH2 
2457 N N   . THR A 160 ? 0.11803 0.23302 0.17193 0.00600  -0.06382 0.01362  174 THR A N   
2458 C CA  . THR A 160 ? 0.13684 0.23783 0.18998 -0.01076 -0.06221 0.01807  174 THR A CA  
2459 C C   . THR A 160 ? 0.15468 0.23707 0.18358 -0.01024 -0.06162 0.01703  174 THR A C   
2460 O O   . THR A 160 ? 0.17671 0.22928 0.20116 -0.01363 -0.06768 0.01544  174 THR A O   
2461 C CB  . THR A 160 ? 0.16395 0.22805 0.18502 -0.02624 -0.04460 0.01973  174 THR A CB  
2462 O OG1 . THR A 160 ? 0.15727 0.21255 0.19621 -0.00501 -0.06349 0.01525  174 THR A OG1 
2463 C CG2 . THR A 160 ? 0.18250 0.23580 0.19235 -0.03132 -0.05257 0.02001  174 THR A CG2 
2471 N N   . ALA A 161 ? 0.16082 0.24909 0.17227 -0.01798 -0.05497 0.01625  175 ALA A N   
2472 C CA  . ALA A 161 ? 0.16810 0.25982 0.18924 -0.01317 -0.04157 0.00341  175 ALA A CA  
2473 C C   . ALA A 161 ? 0.16073 0.24895 0.17470 -0.01586 -0.05877 0.01537  175 ALA A C   
2474 O O   . ALA A 161 ? 0.17115 0.24902 0.20930 -0.00990 -0.05558 0.01476  175 ALA A O   
2475 C CB  . ALA A 161 ? 0.19339 0.27109 0.19598 -0.01156 -0.01403 -0.01482 175 ALA A CB  
2481 N N   . GLY A 162 ? 0.17258 0.24120 0.17194 -0.00736 -0.03383 0.01584  176 GLY A N   
2482 C CA  . GLY A 162 ? 0.16630 0.23393 0.17690 -0.00262 -0.05077 0.01866  176 GLY A CA  
2483 C C   . GLY A 162 ? 0.15275 0.21445 0.16666 0.00069  -0.06299 0.01079  176 GLY A C   
2484 O O   . GLY A 162 ? 0.15834 0.21357 0.16809 0.00375  -0.05692 0.01787  176 GLY A O   
2488 N N   . ALA A 163 ? 0.14872 0.21549 0.15712 0.00005  -0.06999 0.00695  177 ALA A N   
2489 C CA  . ALA A 163 ? 0.13795 0.19996 0.16083 0.00343  -0.07353 0.00198  177 ALA A CA  
2490 C C   . ALA A 163 ? 0.13499 0.17536 0.17110 0.00074  -0.06141 -0.00089 177 ALA A C   
2491 O O   . ALA A 163 ? 0.17095 0.18390 0.18005 -0.00687 -0.06415 0.00937  177 ALA A O   
2492 C CB  . ALA A 163 ? 0.14198 0.21379 0.18732 -0.00715 -0.06496 0.00754  177 ALA A CB  
2498 N N   . MET A 164 ? 0.12508 0.16702 0.15165 -0.00926 -0.06026 0.00269  178 MET A N   
2499 C CA  . MET A 164 ? 0.11328 0.16843 0.14614 -0.00779 -0.06432 -0.00009 178 MET A CA  
2500 C C   . MET A 164 ? 0.10408 0.14686 0.16666 -0.00363 -0.07216 -0.00043 178 MET A C   
2501 O O   . MET A 164 ? 0.12079 0.14353 0.16854 -0.00664 -0.05766 0.00548  178 MET A O   
2502 C CB  . MET A 164 ? 0.09857 0.18681 0.15539 -0.00377 -0.07020 0.00306  178 MET A CB  
2503 C CG  . MET A 164 ? 0.12186 0.18879 0.17489 -0.00111 -0.06247 0.01320  178 MET A CG  
2504 S SD  . MET A 164 ? 0.12437 0.17901 0.18197 0.00257  -0.05857 -0.00066 178 MET A SD  
2505 C CE  . MET A 164 ? 0.14257 0.18604 0.18253 -0.00475 -0.04920 -0.00217 178 MET A CE  
2515 N N   . SER A 165 ? 0.11113 0.14479 0.15738 -0.00340 -0.05541 -0.00567 179 SER A N   
2516 C CA  . SER A 165 ? 0.11027 0.15847 0.16591 -0.00751 -0.06460 -0.00071 179 SER A CA  
2517 C C   . SER A 165 ? 0.10320 0.13823 0.16780 -0.01786 -0.06941 -0.00583 179 SER A C   
2518 O O   . SER A 165 ? 0.10815 0.15456 0.16770 -0.01272 -0.06195 0.00094  179 SER A O   
2519 C CB  . SER A 165 ? 0.11080 0.18341 0.18584 0.01393  -0.07250 0.00736  179 SER A CB  
2520 O OG  . SER A 165 ? 0.14232 0.17762 0.22256 0.02453  -0.06315 0.00382  179 SER A OG  
2526 N N   . PHE A 166 ? 0.10396 0.14683 0.16239 -0.01337 -0.05081 -0.00411 180 PHE A N   
2527 C CA  . PHE A 166 ? 0.13254 0.15584 0.14278 -0.00924 -0.05561 -0.00635 180 PHE A CA  
2528 C C   . PHE A 166 ? 0.11949 0.17109 0.15281 -0.01221 -0.05613 -0.00570 180 PHE A C   
2529 O O   . PHE A 166 ? 0.09765 0.19116 0.17463 -0.01746 -0.05875 -0.01398 180 PHE A O   
2530 C CB  . PHE A 166 ? 0.15219 0.15154 0.16933 0.00595  -0.05253 0.00818  180 PHE A CB  
2531 C CG  . PHE A 166 ? 0.12914 0.14645 0.17353 0.00722  -0.06283 0.01243  180 PHE A CG  
2532 C CD1 . PHE A 166 ? 0.13799 0.15189 0.18232 0.00085  -0.05413 -0.00037 180 PHE A CD1 
2533 C CD2 . PHE A 166 ? 0.14009 0.16374 0.18551 0.01939  -0.07316 0.01423  180 PHE A CD2 
2534 C CE1 . PHE A 166 ? 0.13855 0.15527 0.19068 0.00708  -0.04508 0.00606  180 PHE A CE1 
2535 C CE2 . PHE A 166 ? 0.13644 0.17272 0.18335 0.01872  -0.06625 0.00843  180 PHE A CE2 
2536 C CZ  . PHE A 166 ? 0.12839 0.16595 0.17980 0.01481  -0.04808 0.00390  180 PHE A CZ  
2546 N N   . GLN A 167 ? 0.10531 0.16262 0.15913 -0.01077 -0.05921 -0.01362 181 GLN A N   
2547 C CA  . GLN A 167 ? 0.10686 0.18123 0.17010 0.01021  -0.05646 -0.02028 181 GLN A CA  
2548 C C   . GLN A 167 ? 0.10393 0.18490 0.16494 -0.00876 -0.06735 -0.02019 181 GLN A C   
2549 O O   . GLN A 167 ? 0.12523 0.20226 0.17826 -0.02752 -0.06307 -0.00626 181 GLN A O   
2550 C CB  . GLN A 167 ? 0.12539 0.20597 0.19321 0.02772  -0.06156 -0.02271 181 GLN A CB  
2551 C CG  . GLN A 167 ? 0.15030 0.22992 0.20960 0.05071  -0.06983 -0.03242 181 GLN A CG  
2552 C CD  . GLN A 167 ? 0.19414 0.26426 0.23430 0.06757  -0.09353 -0.02517 181 GLN A CD  
2553 O OE1 . GLN A 167 ? 0.21093 0.28794 0.26965 0.07676  -0.09824 -0.01480 181 GLN A OE1 
2554 N NE2 . GLN A 167 ? 0.24625 0.27393 0.27240 0.07230  -0.05141 -0.04263 181 GLN A NE2 
2563 N N   . ILE A 168 ? 0.10000 0.18287 0.17544 -0.01473 -0.07029 -0.01449 182 ILE A N   
2564 C CA  . ILE A 168 ? 0.09324 0.18658 0.17889 -0.00433 -0.06347 -0.01723 182 ILE A CA  
2565 C C   . ILE A 168 ? 0.10213 0.20349 0.17266 0.00287  -0.06742 -0.02162 182 ILE A C   
2566 O O   . ILE A 168 ? 0.09663 0.21847 0.20639 -0.00060 -0.05566 -0.03036 182 ILE A O   
2567 C CB  . ILE A 168 ? 0.10563 0.18015 0.16720 -0.00392 -0.06488 -0.01782 182 ILE A CB  
2568 C CG1 . ILE A 168 ? 0.12687 0.19193 0.20418 0.00171  -0.03436 -0.02878 182 ILE A CG1 
2569 C CG2 . ILE A 168 ? 0.14510 0.19577 0.19546 -0.01141 -0.06912 -0.00286 182 ILE A CG2 
2570 C CD1 . ILE A 168 ? 0.12170 0.20342 0.20079 0.00014  -0.05523 -0.02714 182 ILE A CD1 
2582 N N   . ASP A 169 ? 0.10870 0.19478 0.17148 0.00560  -0.05643 -0.03112 183 ASP A N   
2583 C CA  . ASP A 169 ? 0.11546 0.21098 0.18706 0.01736  -0.06480 -0.02488 183 ASP A CA  
2584 C C   . ASP A 169 ? 0.12025 0.22234 0.17906 0.01152  -0.05372 -0.03317 183 ASP A C   
2585 O O   . ASP A 169 ? 0.11760 0.23503 0.19139 -0.00125 -0.06044 -0.03662 183 ASP A O   
2586 C CB  . ASP A 169 ? 0.15399 0.22708 0.22080 0.03628  -0.04539 -0.02266 183 ASP A CB  
2587 C CG  . ASP A 169 ? 0.16425 0.25207 0.27506 0.02938  -0.05128 -0.00474 183 ASP A CG  
2588 O OD1 . ASP A 169 ? 0.18205 0.27113 0.32278 0.01942  -0.07246 0.01401  183 ASP A OD1 
2589 O OD2 . ASP A 169 ? 0.18297 0.26626 0.26570 0.01513  -0.03975 0.00809  183 ASP A OD2 
2594 N N   . VAL A 170 ? 0.11213 0.22486 0.18622 0.00440  -0.05317 -0.03856 184 VAL A N   
2595 C CA  . VAL A 170 ? 0.14101 0.23712 0.17930 0.01625  -0.04669 -0.04256 184 VAL A CA  
2596 C C   . VAL A 170 ? 0.14172 0.24957 0.18429 0.02630  -0.05719 -0.05137 184 VAL A C   
2597 O O   . VAL A 170 ? 0.15363 0.26800 0.21148 0.01478  -0.04634 -0.04812 184 VAL A O   
2598 C CB  . VAL A 170 ? 0.17110 0.24307 0.18965 0.02117  -0.03710 -0.03277 184 VAL A CB  
2599 C CG1 . VAL A 170 ? 0.19636 0.25096 0.19624 0.02403  -0.03119 -0.00919 184 VAL A CG1 
2600 C CG2 . VAL A 170 ? 0.19770 0.24228 0.20969 0.03662  -0.01271 -0.01396 184 VAL A CG2 
2610 N N   . LYS A 171 ? 0.17400 0.26712 0.21466 0.03032  -0.06355 -0.07964 185 LYS A N   
2611 C CA  A LYS A 171 ? 0.19877 0.27815 0.24297 0.03416  -0.04783 -0.08200 185 LYS A CA  
2612 C CA  B LYS A 171 ? 0.21729 0.28232 0.25643 0.04602  -0.05573 -0.08396 185 LYS A CA  
2613 C C   . LYS A 171 ? 0.21998 0.28575 0.25109 0.03762  -0.04382 -0.08325 185 LYS A C   
2614 O O   . LYS A 171 ? 0.21427 0.27693 0.23491 0.02713  -0.05611 -0.07962 185 LYS A O   
2615 C CB  A LYS A 171 ? 0.20334 0.28118 0.26265 0.03446  -0.03639 -0.08288 185 LYS A CB  
2616 C CB  B LYS A 171 ? 0.27337 0.28710 0.29555 0.07227  -0.05715 -0.08221 185 LYS A CB  
2617 C CG  A LYS A 171 ? 0.20801 0.28438 0.28182 0.03409  -0.02574 -0.08279 185 LYS A CG  
2618 C CG  B LYS A 171 ? 0.35469 0.30481 0.37426 0.08649  -0.03696 -0.06289 185 LYS A CG  
2619 C CD  A LYS A 171 ? 0.21182 0.28702 0.29774 0.03354  -0.01605 -0.08219 185 LYS A CD  
2620 C CD  B LYS A 171 ? 0.42931 0.32222 0.43691 0.09188  -0.01392 -0.04783 185 LYS A CD  
2621 C CE  A LYS A 171 ? 0.21488 0.28920 0.31003 0.03336  -0.00708 -0.08118 185 LYS A CE  
2622 C CE  B LYS A 171 ? 0.49133 0.34048 0.49467 0.09523  0.01832  -0.03250 185 LYS A CE  
2623 N NZ  A LYS A 171 ? 0.21564 0.29021 0.31593 0.03290  -0.00195 -0.08097 185 LYS A NZ  
2624 N NZ  B LYS A 171 ? 0.52476 0.35016 0.52027 0.09513  0.03685  -0.02302 185 LYS A NZ  
2649 N N   . ASP A 172 ? 0.23490 0.30991 0.24626 0.03666  -0.04437 -0.08498 186 ASP A N   
2650 C CA  . ASP A 172 ? 0.25677 0.32612 0.24865 0.02153  -0.04640 -0.10688 186 ASP A CA  
2651 C C   . ASP A 172 ? 0.24093 0.32886 0.21852 0.00644  -0.04585 -0.08498 186 ASP A C   
2652 O O   . ASP A 172 ? 0.24770 0.33311 0.22049 -0.00015 -0.04632 -0.09224 186 ASP A O   
2653 C CB  . ASP A 172 ? 0.29055 0.34092 0.29380 0.02510  -0.03919 -0.12642 186 ASP A CB  
2654 C CG  . ASP A 172 ? 0.34435 0.36327 0.37670 0.02526  -0.00353 -0.12277 186 ASP A CG  
2655 O OD1 . ASP A 172 ? 0.36155 0.37629 0.39250 0.03578  0.02194  -0.13326 186 ASP A OD1 
2656 O OD2 . ASP A 172 ? 0.36871 0.37239 0.42466 0.02508  0.00465  -0.11198 186 ASP A OD2 
2661 N N   . SER A 173 ? 0.21876 0.31986 0.19685 -0.00621 -0.04751 -0.05507 187 SER A N   
2662 C CA  . SER A 173 ? 0.20224 0.31808 0.19800 -0.00510 -0.05867 -0.03896 187 SER A CA  
2663 C C   . SER A 173 ? 0.18797 0.29116 0.18152 -0.00012 -0.07176 -0.03113 187 SER A C   
2664 O O   . SER A 173 ? 0.19059 0.30225 0.20974 0.01092  -0.06297 -0.02387 187 SER A O   
2665 C CB  . SER A 173 ? 0.22774 0.34385 0.19805 -0.00386 -0.03908 -0.03231 187 SER A CB  
2666 O OG  . SER A 173 ? 0.24327 0.36315 0.20811 0.00126  -0.01331 -0.03440 187 SER A OG  
2672 N N   . LYS A 174 ? 0.18127 0.26420 0.18105 -0.01454 -0.05997 -0.05075 188 LYS A N   
2673 C CA  . LYS A 174 ? 0.20653 0.25815 0.18337 -0.02653 -0.05938 -0.05691 188 LYS A CA  
2674 C C   . LYS A 174 ? 0.15557 0.24303 0.17263 -0.00918 -0.07762 -0.05052 188 LYS A C   
2675 O O   . LYS A 174 ? 0.14392 0.26825 0.20073 -0.00184 -0.06928 -0.06830 188 LYS A O   
2676 C CB  . LYS A 174 ? 0.29581 0.26983 0.21687 -0.04751 -0.03655 -0.06900 188 LYS A CB  
2677 C CG  . LYS A 174 ? 0.38534 0.28607 0.25733 -0.06047 -0.02071 -0.07251 188 LYS A CG  
2678 C CD  . LYS A 174 ? 0.45396 0.31240 0.31476 -0.06541 -0.01601 -0.06167 188 LYS A CD  
2679 C CE  . LYS A 174 ? 0.51325 0.33282 0.37351 -0.06653 0.00555  -0.05846 188 LYS A CE  
2680 N NZ  . LYS A 174 ? 0.54707 0.34277 0.41021 -0.06459 0.01926  -0.05853 188 LYS A NZ  
2694 N N   . LEU A 175 ? 0.14740 0.21239 0.15947 -0.00197 -0.06169 -0.02410 189 LEU A N   
2695 C CA  . LEU A 175 ? 0.13136 0.19921 0.16597 -0.00603 -0.05566 -0.02465 189 LEU A CA  
2696 C C   . LEU A 175 ? 0.11717 0.18418 0.17167 -0.00025 -0.07250 -0.03570 189 LEU A C   
2697 O O   . LEU A 175 ? 0.13150 0.18285 0.18536 -0.00480 -0.06889 -0.01162 189 LEU A O   
2698 C CB  . LEU A 175 ? 0.12344 0.20016 0.18077 -0.00125 -0.06198 -0.01368 189 LEU A CB  
2699 C CG  . LEU A 175 ? 0.11088 0.19443 0.18128 0.00877  -0.07249 -0.01772 189 LEU A CG  
2700 C CD1 . LEU A 175 ? 0.10910 0.19082 0.21040 0.00438  -0.06638 -0.01915 189 LEU A CD1 
2701 C CD2 . LEU A 175 ? 0.12452 0.20372 0.21726 0.02791  -0.06774 -0.02162 189 LEU A CD2 
2713 N N   . THR A 176 ? 0.11402 0.17281 0.18273 -0.00148 -0.06250 -0.02305 190 THR A N   
2714 C CA  . THR A 176 ? 0.13019 0.16724 0.19125 0.00457  -0.06680 -0.01635 190 THR A CA  
2715 C C   . THR A 176 ? 0.11119 0.16216 0.17623 -0.00190 -0.06794 -0.01052 190 THR A C   
2716 O O   . THR A 176 ? 0.11398 0.19649 0.19220 -0.01082 -0.05679 -0.02731 190 THR A O   
2717 C CB  . THR A 176 ? 0.16427 0.17730 0.21258 0.01921  -0.08423 -0.01888 190 THR A CB  
2718 O OG1 . THR A 176 ? 0.21549 0.18845 0.22502 0.02791  -0.08089 -0.03100 190 THR A OG1 
2719 C CG2 . THR A 176 ? 0.17202 0.18036 0.24696 0.02173  -0.07152 -0.01193 190 THR A CG2 
2727 N N   . ILE A 177 ? 0.10266 0.15017 0.16871 0.00387  -0.06772 -0.01028 191 ILE A N   
2728 C CA  . ILE A 177 ? 0.10047 0.13699 0.17769 -0.00893 -0.05808 -0.00253 191 ILE A CA  
2729 C C   . ILE A 177 ? 0.10102 0.14052 0.19688 -0.01101 -0.05726 -0.00872 191 ILE A C   
2730 O O   . ILE A 177 ? 0.10811 0.14999 0.18336 -0.00706 -0.06306 0.00658  191 ILE A O   
2731 C CB  . ILE A 177 ? 0.11630 0.13855 0.17434 0.00286  -0.05641 -0.00827 191 ILE A CB  
2732 C CG1 . ILE A 177 ? 0.12904 0.14683 0.18209 0.00812  -0.05146 0.00615  191 ILE A CG1 
2733 C CG2 . ILE A 177 ? 0.12504 0.15032 0.19754 0.01291  -0.04541 -0.00866 191 ILE A CG2 
2734 C CD1 . ILE A 177 ? 0.14221 0.15074 0.20512 0.01221  -0.04529 0.00982  191 ILE A CD1 
2746 N N   . THR A 178 ? 0.09415 0.13704 0.19033 -0.00986 -0.06945 0.00265  192 THR A N   
2747 C CA  . THR A 178 ? 0.10201 0.14030 0.18158 0.00519  -0.07411 0.00827  192 THR A CA  
2748 C C   . THR A 178 ? 0.10859 0.14254 0.18717 -0.00275 -0.06146 0.00788  192 THR A C   
2749 O O   . THR A 178 ? 0.12224 0.17183 0.17662 -0.02994 -0.05059 -0.01523 192 THR A O   
2750 C CB  . THR A 178 ? 0.11613 0.14928 0.18681 0.01607  -0.07033 -0.00127 192 THR A CB  
2751 O OG1 . THR A 178 ? 0.14530 0.15335 0.20340 0.02813  -0.06573 -0.01992 192 THR A OG1 
2752 C CG2 . THR A 178 ? 0.13202 0.16208 0.19418 0.02764  -0.05004 0.00465  192 THR A CG2 
2760 N N   . VAL A 179 ? 0.09916 0.13266 0.18250 -0.00288 -0.07323 0.00336  193 VAL A N   
2761 C CA  . VAL A 179 ? 0.09994 0.15098 0.18788 0.00363  -0.05884 0.00914  193 VAL A CA  
2762 C C   . VAL A 179 ? 0.09350 0.14233 0.19711 -0.00784 -0.05657 -0.00406 193 VAL A C   
2763 O O   . VAL A 179 ? 0.11792 0.14057 0.18430 -0.00580 -0.05024 -0.00047 193 VAL A O   
2764 C CB  . VAL A 179 ? 0.11865 0.16624 0.20639 0.01762  -0.05211 0.00856  193 VAL A CB  
2765 C CG1 . VAL A 179 ? 0.13201 0.18416 0.23337 0.02202  -0.03336 -0.01994 193 VAL A CG1 
2766 C CG2 . VAL A 179 ? 0.15746 0.17569 0.25655 0.03688  -0.03941 0.01769  193 VAL A CG2 
2776 N N   . ASN A 180 ? 0.11321 0.14532 0.17457 -0.00394 -0.05756 0.00700  194 ASN A N   
2777 C CA  . ASN A 180 ? 0.14885 0.15419 0.17463 -0.00642 -0.07062 0.00340  194 ASN A CA  
2778 C C   . ASN A 180 ? 0.12635 0.14698 0.18375 0.00126  -0.08181 0.02010  194 ASN A C   
2779 O O   . ASN A 180 ? 0.16588 0.14976 0.18931 -0.00249 -0.05973 0.02328  194 ASN A O   
2780 C CB  . ASN A 180 ? 0.16750 0.16789 0.17585 -0.00899 -0.04457 0.00326  194 ASN A CB  
2781 C CG  . ASN A 180 ? 0.15221 0.16620 0.17979 -0.01161 -0.04493 0.01770  194 ASN A CG  
2782 O OD1 . ASN A 180 ? 0.15506 0.17491 0.18719 -0.02707 -0.05428 0.01096  194 ASN A OD1 
2783 N ND2 . ASN A 180 ? 0.15431 0.17252 0.22126 -0.02004 -0.03133 0.00391  194 ASN A ND2 
2790 N N   . GLY A 181 ? 0.11982 0.15257 0.19634 0.00025  -0.07917 0.01494  195 GLY A N   
2791 C CA  . GLY A 181 ? 0.12103 0.15365 0.20891 0.00902  -0.08728 0.00605  195 GLY A CA  
2792 C C   . GLY A 181 ? 0.12791 0.15919 0.20302 0.01223  -0.08709 -0.00173 195 GLY A C   
2793 O O   . GLY A 181 ? 0.14859 0.15992 0.21397 0.02996  -0.08033 -0.01152 195 GLY A O   
2797 N N   . ASN A 182 ? 0.11635 0.14499 0.20522 0.00236  -0.08531 -0.00613 196 ASN A N   
2798 C CA  . ASN A 182 ? 0.12226 0.14907 0.21880 0.00725  -0.07647 -0.00096 196 ASN A CA  
2799 C C   . ASN A 182 ? 0.12540 0.13750 0.21392 0.01144  -0.07329 -0.00836 196 ASN A C   
2800 O O   . ASN A 182 ? 0.12485 0.12528 0.20681 0.00824  -0.07704 -0.00001 196 ASN A O   
2801 C CB  . ASN A 182 ? 0.12353 0.15974 0.22850 0.00479  -0.06108 -0.01465 196 ASN A CB  
2802 C CG  . ASN A 182 ? 0.12870 0.17916 0.24140 0.02057  -0.05849 -0.01829 196 ASN A CG  
2803 O OD1 . ASN A 182 ? 0.13661 0.16562 0.22914 0.00926  -0.06669 -0.01232 196 ASN A OD1 
2804 N ND2 . ASN A 182 ? 0.16465 0.22345 0.32040 0.02113  -0.05981 -0.02887 196 ASN A ND2 
2811 N N   . VAL A 183 ? 0.13539 0.14033 0.19655 0.00899  -0.08048 -0.00546 197 VAL A N   
2812 C CA  . VAL A 183 ? 0.13073 0.15254 0.20669 0.01087  -0.08791 0.00599  197 VAL A CA  
2813 C C   . VAL A 183 ? 0.12505 0.16564 0.24031 -0.01564 -0.08325 0.00515  197 VAL A C   
2814 O O   . VAL A 183 ? 0.13600 0.18611 0.29975 -0.02300 -0.07951 0.02760  197 VAL A O   
2815 C CB  . VAL A 183 ? 0.16785 0.15003 0.19095 0.01810  -0.08203 0.00319  197 VAL A CB  
2816 C CG1 . VAL A 183 ? 0.19194 0.15567 0.19423 0.02850  -0.06971 0.00475  197 VAL A CG1 
2817 C CG2 . VAL A 183 ? 0.17286 0.17975 0.18483 0.02162  -0.07280 0.00171  197 VAL A CG2 
2827 N N   . VAL A 184 ? 0.10361 0.16726 0.20240 0.00087  -0.07697 0.00583  198 VAL A N   
2828 C CA  A VAL A 184 ? 0.11065 0.18640 0.21337 0.01031  -0.07931 0.00378  198 VAL A CA  
2829 C CA  B VAL A 184 ? 0.10923 0.18424 0.22104 0.00535  -0.07179 0.00537  198 VAL A CA  
2830 C C   . VAL A 184 ? 0.11332 0.19928 0.21869 0.00511  -0.08200 0.00207  198 VAL A C   
2831 O O   . VAL A 184 ? 0.12915 0.24789 0.25613 0.01145  -0.09030 0.02930  198 VAL A O   
2832 C CB  A VAL A 184 ? 0.13277 0.19808 0.21564 0.02918  -0.05740 0.00018  198 VAL A CB  
2833 C CB  B VAL A 184 ? 0.11704 0.18836 0.24101 0.01137  -0.04750 0.00704  198 VAL A CB  
2834 C CG1 A VAL A 184 ? 0.14288 0.20630 0.19860 0.02410  -0.05070 0.00195  198 VAL A CG1 
2835 C CG1 B VAL A 184 ? 0.12351 0.19073 0.26832 0.01587  -0.03247 0.00470  198 VAL A CG1 
2836 C CG2 A VAL A 184 ? 0.14161 0.20190 0.22102 0.03949  -0.08173 -0.02756 198 VAL A CG2 
2837 C CG2 B VAL A 184 ? 0.11597 0.18998 0.23186 0.00851  -0.04957 0.00415  198 VAL A CG2 
2854 N N   . VAL A 185 ? 0.12005 0.16992 0.20231 0.01073  -0.06587 -0.00098 199 VAL A N   
2855 C CA  . VAL A 185 ? 0.12566 0.15747 0.18998 0.00611  -0.07391 -0.00422 199 VAL A CA  
2856 C C   . VAL A 185 ? 0.12942 0.15351 0.18924 0.00296  -0.09039 -0.00834 199 VAL A C   
2857 O O   . VAL A 185 ? 0.12114 0.15033 0.19186 0.00306  -0.08451 -0.00625 199 VAL A O   
2858 C CB  . VAL A 185 ? 0.13175 0.16250 0.20107 0.01075  -0.06899 -0.00043 199 VAL A CB  
2859 C CG1 . VAL A 185 ? 0.14273 0.16702 0.20806 0.02678  -0.06965 0.00302  199 VAL A CG1 
2860 C CG2 . VAL A 185 ? 0.14275 0.17919 0.19766 0.00949  -0.05418 0.00308  199 VAL A CG2 
2870 N N   . ASN A 186 ? 0.14384 0.15871 0.20030 0.00543  -0.09237 -0.01951 200 ASN A N   
2871 C CA  . ASN A 186 ? 0.15353 0.16565 0.21892 0.00070  -0.08533 -0.01852 200 ASN A CA  
2872 C C   . ASN A 186 ? 0.16167 0.18332 0.23597 -0.00859 -0.08864 -0.01700 200 ASN A C   
2873 O O   . ASN A 186 ? 0.18463 0.21809 0.23514 -0.02643 -0.10280 -0.01440 200 ASN A O   
2874 C CB  . ASN A 186 ? 0.16322 0.16964 0.22447 0.00170  -0.07831 -0.00598 200 ASN A CB  
2875 C CG  . ASN A 186 ? 0.19079 0.17038 0.25087 0.00188  -0.07043 0.00207  200 ASN A CG  
2876 O OD1 . ASN A 186 ? 0.20324 0.15819 0.25566 0.00241  -0.07128 -0.00621 200 ASN A OD1 
2877 N ND2 . ASN A 186 ? 0.22608 0.17686 0.28971 0.00224  -0.01740 0.00606  200 ASN A ND2 
2884 N N   . GLY A 187 ? 0.17717 0.18904 0.23303 -0.00972 -0.06954 -0.01346 201 GLY A N   
2885 C CA  . GLY A 187 ? 0.19246 0.21607 0.22875 0.00205  -0.05994 -0.00973 201 GLY A CA  
2886 C C   . GLY A 187 ? 0.20336 0.23374 0.20401 -0.02161 -0.08238 -0.02276 201 GLY A C   
2887 O O   . GLY A 187 ? 0.24746 0.24318 0.21725 -0.02385 -0.09518 -0.03171 201 GLY A O   
2891 N N   . GLN A 188 ? 0.17747 0.23521 0.18451 -0.02887 -0.08446 -0.00891 202 GLN A N   
2892 C CA  . GLN A 188 ? 0.14650 0.24485 0.17451 -0.02380 -0.08347 0.00366  202 GLN A CA  
2893 C C   . GLN A 188 ? 0.14061 0.26144 0.18708 -0.01978 -0.08648 0.01163  202 GLN A C   
2894 O O   . GLN A 188 ? 0.14959 0.26440 0.19428 -0.02581 -0.06981 0.00630  202 GLN A O   
2895 C CB  . GLN A 188 ? 0.14741 0.23715 0.18282 -0.02186 -0.08066 0.00739  202 GLN A CB  
2896 C CG  . GLN A 188 ? 0.14140 0.23673 0.19121 -0.01014 -0.07277 0.00683  202 GLN A CG  
2897 C CD  . GLN A 188 ? 0.14293 0.25520 0.20420 -0.00997 -0.06580 0.00340  202 GLN A CD  
2898 O OE1 . GLN A 188 ? 0.13773 0.26245 0.22101 0.00617  -0.05556 0.01133  202 GLN A OE1 
2899 N NE2 . GLN A 188 ? 0.15895 0.26468 0.20403 -0.00430 -0.07779 0.01732  202 GLN A NE2 
2908 N N   . ASP A 189 ? 0.16490 0.27930 0.18974 -0.03942 -0.07995 0.02048  203 ASP A N   
2909 C CA  . ASP A 189 ? 0.17740 0.30892 0.19357 -0.03553 -0.07816 0.01252  203 ASP A CA  
2910 C C   . ASP A 189 ? 0.17930 0.30204 0.21101 -0.01766 -0.04085 0.01429  203 ASP A C   
2911 O O   . ASP A 189 ? 0.19228 0.30176 0.26398 -0.00058 -0.01405 0.05186  203 ASP A O   
2912 C CB  . ASP A 189 ? 0.20354 0.34204 0.21128 -0.04687 -0.09870 -0.00298 203 ASP A CB  
2913 C CG  . ASP A 189 ? 0.24634 0.36908 0.23940 -0.04917 -0.10197 -0.01959 203 ASP A CG  
2914 O OD1 . ASP A 189 ? 0.27023 0.36823 0.25535 -0.05420 -0.06269 -0.03306 203 ASP A OD1 
2915 O OD2 . ASP A 189 ? 0.27793 0.39493 0.26851 -0.03761 -0.09001 -0.00297 203 ASP A OD2 
2920 N N   . LEU A 190 ? 0.15806 0.29620 0.17045 -0.02347 -0.06443 -0.00978 204 LEU A N   
2921 C CA  . LEU A 190 ? 0.15597 0.30758 0.17946 -0.02504 -0.06681 -0.00283 204 LEU A CA  
2922 C C   . LEU A 190 ? 0.16661 0.32057 0.17724 -0.02981 -0.07454 0.00488  204 LEU A C   
2923 O O   . LEU A 190 ? 0.16457 0.32895 0.19488 -0.03540 -0.07196 0.01313  204 LEU A O   
2924 C CB  . LEU A 190 ? 0.17198 0.31598 0.17885 -0.03441 -0.07046 0.01169  204 LEU A CB  
2925 C CG  . LEU A 190 ? 0.19523 0.33369 0.19360 -0.03693 -0.07499 0.02948  204 LEU A CG  
2926 C CD1 . LEU A 190 ? 0.20517 0.34484 0.20272 -0.06033 -0.08226 0.02312  204 LEU A CD1 
2927 C CD2 . LEU A 190 ? 0.24389 0.34586 0.21933 -0.01884 -0.04648 0.02134  204 LEU A CD2 
2939 N N   . SER A 191 ? 0.19411 0.32753 0.16010 -0.04330 -0.06245 -0.00633 205 SER A N   
2940 C CA  . SER A 191 ? 0.22893 0.34134 0.17447 -0.04748 -0.05445 -0.01063 205 SER A CA  
2941 C C   . SER A 191 ? 0.21106 0.34557 0.18358 -0.05771 -0.07970 -0.01300 205 SER A C   
2942 O O   . SER A 191 ? 0.21826 0.34967 0.17946 -0.06264 -0.06284 -0.01680 205 SER A O   
2943 C CB  . SER A 191 ? 0.27636 0.34899 0.21367 -0.04809 -0.04394 -0.02003 205 SER A CB  
2944 O OG  . SER A 191 ? 0.30681 0.35690 0.24120 -0.05341 -0.05870 -0.02811 205 SER A OG  
2950 N N   . PHE A 192 ? 0.19641 0.34921 0.17884 -0.04883 -0.09165 0.01787  206 PHE A N   
2951 C CA  . PHE A 192 ? 0.19378 0.35176 0.16981 -0.05274 -0.07617 0.02436  206 PHE A CA  
2952 C C   . PHE A 192 ? 0.18697 0.34900 0.17212 -0.05084 -0.07335 0.03402  206 PHE A C   
2953 O O   . PHE A 192 ? 0.19456 0.35186 0.20133 -0.06340 -0.08001 0.04297  206 PHE A O   
2954 C CB  . PHE A 192 ? 0.17657 0.35251 0.19424 -0.04976 -0.08812 0.02720  206 PHE A CB  
2955 C CG  . PHE A 192 ? 0.17783 0.35134 0.19741 -0.04798 -0.08964 0.04168  206 PHE A CG  
2956 C CD1 . PHE A 192 ? 0.19728 0.35794 0.21360 -0.04980 -0.09729 0.05720  206 PHE A CD1 
2957 C CD2 . PHE A 192 ? 0.18391 0.36383 0.23269 -0.04634 -0.09863 0.02720  206 PHE A CD2 
2958 C CE1 . PHE A 192 ? 0.21638 0.35871 0.21444 -0.04865 -0.10401 0.05465  206 PHE A CE1 
2959 C CE2 . PHE A 192 ? 0.19025 0.36027 0.24961 -0.06158 -0.09516 0.02140  206 PHE A CE2 
2960 C CZ  . PHE A 192 ? 0.21304 0.35663 0.23873 -0.05674 -0.08569 0.03780  206 PHE A CZ  
2970 N N   . TRP A 193 ? 0.15881 0.34171 0.17425 -0.05139 -0.06023 0.00597  207 TRP A N   
2971 C CA  . TRP A 193 ? 0.16885 0.34137 0.15660 -0.05821 -0.05450 0.00028  207 TRP A CA  
2972 C C   . TRP A 193 ? 0.18795 0.34861 0.16866 -0.06132 -0.05683 -0.01134 207 TRP A C   
2973 O O   . TRP A 193 ? 0.17555 0.35021 0.18031 -0.06607 -0.04844 -0.00461 207 TRP A O   
2974 C CB  . TRP A 193 ? 0.15801 0.33767 0.17041 -0.05591 -0.03896 0.00167  207 TRP A CB  
2975 C CG  . TRP A 193 ? 0.13841 0.32970 0.16114 -0.05427 -0.05584 0.00896  207 TRP A CG  
2976 C CD1 . TRP A 193 ? 0.15008 0.32362 0.15711 -0.04466 -0.06554 0.00674  207 TRP A CD1 
2977 C CD2 . TRP A 193 ? 0.14885 0.33094 0.17976 -0.04605 -0.06305 0.00919  207 TRP A CD2 
2978 N NE1 . TRP A 193 ? 0.14166 0.33094 0.16422 -0.04377 -0.06268 0.01145  207 TRP A NE1 
2979 C CE2 . TRP A 193 ? 0.15255 0.32239 0.16990 -0.02685 -0.07697 0.01779  207 TRP A CE2 
2980 C CE3 . TRP A 193 ? 0.17327 0.32600 0.18141 -0.04109 -0.07437 0.00848  207 TRP A CE3 
2981 C CZ2 . TRP A 193 ? 0.17745 0.33770 0.20230 -0.02408 -0.06507 0.00948  207 TRP A CZ2 
2982 C CZ3 . TRP A 193 ? 0.20161 0.33191 0.19999 -0.03622 -0.07247 0.00861  207 TRP A CZ3 
2983 C CH2 . TRP A 193 ? 0.19948 0.33589 0.21143 -0.02991 -0.06824 0.00151  207 TRP A CH2 
2994 N N   . ASP A 194 ? 0.21302 0.35674 0.17203 -0.06565 -0.03834 -0.01488 208 ASP A N   
2995 C CA  . ASP A 194 ? 0.24031 0.36648 0.19346 -0.07295 -0.02335 -0.02015 208 ASP A CA  
2996 C C   . ASP A 194 ? 0.25309 0.37835 0.19463 -0.06477 -0.02538 -0.01124 208 ASP A C   
2997 O O   . ASP A 194 ? 0.29383 0.38426 0.19177 -0.05440 -0.01841 -0.00114 208 ASP A O   
2998 C CB  . ASP A 194 ? 0.26836 0.36717 0.20411 -0.07721 -0.03320 -0.03391 208 ASP A CB  
2999 C CG  . ASP A 194 ? 0.30486 0.37807 0.22440 -0.07410 -0.03208 -0.04117 208 ASP A CG  
3000 O OD1 . ASP A 194 ? 0.30618 0.38706 0.23174 -0.06317 -0.04238 -0.03121 208 ASP A OD1 
3001 O OD2 . ASP A 194 ? 0.33863 0.38365 0.27471 -0.07598 -0.02704 -0.05120 208 ASP A OD2 
3006 N N   . GLY A 195 ? 0.25232 0.38629 0.21419 -0.06360 0.01083  -0.01411 209 GLY A N   
3007 C CA  . GLY A 195 ? 0.25178 0.38996 0.21411 -0.06667 0.01154  -0.01285 209 GLY A CA  
3008 C C   . GLY A 195 ? 0.22809 0.39257 0.19627 -0.06718 -0.00790 -0.00079 209 GLY A C   
3009 O O   . GLY A 195 ? 0.25558 0.40254 0.18775 -0.06633 0.01031  0.01243  209 GLY A O   
3013 N N   . THR A 196 ? 0.19630 0.38802 0.19241 -0.06227 -0.03095 0.01129  210 THR A N   
3014 C CA  . THR A 196 ? 0.18312 0.39050 0.18455 -0.06700 -0.04630 0.01435  210 THR A CA  
3015 C C   . THR A 196 ? 0.18635 0.39932 0.19247 -0.06248 -0.04470 0.02145  210 THR A C   
3016 O O   . THR A 196 ? 0.19551 0.40325 0.22780 -0.06293 -0.04782 0.05380  210 THR A O   
3017 C CB  . THR A 196 ? 0.19750 0.38969 0.20161 -0.05610 -0.04100 0.02798  210 THR A CB  
3018 O OG1 . THR A 196 ? 0.20565 0.39678 0.23159 -0.03612 -0.04486 0.03203  210 THR A OG1 
3019 C CG2 . THR A 196 ? 0.21616 0.39294 0.23113 -0.05925 -0.02837 0.01616  210 THR A CG2 
3027 N N   . ASP A 197 ? 0.17908 0.40078 0.17090 -0.05490 -0.02594 -0.00876 211 ASP A N   
3028 C CA  . ASP A 197 ? 0.18447 0.40471 0.18287 -0.05405 -0.03213 -0.03787 211 ASP A CA  
3029 C C   . ASP A 197 ? 0.17554 0.38461 0.16804 -0.05119 -0.03882 -0.02147 211 ASP A C   
3030 O O   . ASP A 197 ? 0.18098 0.39129 0.17647 -0.04394 -0.02807 -0.02693 211 ASP A O   
3031 C CB  . ASP A 197 ? 0.22138 0.42916 0.19904 -0.05232 -0.01278 -0.06038 211 ASP A CB  
3032 C CG  . ASP A 197 ? 0.24950 0.44738 0.24277 -0.05469 0.00344  -0.05506 211 ASP A CG  
3033 O OD1 . ASP A 197 ? 0.28553 0.45300 0.30202 -0.05374 0.02057  -0.05310 211 ASP A OD1 
3034 O OD2 . ASP A 197 ? 0.24919 0.45756 0.25004 -0.05141 0.01437  -0.05225 211 ASP A OD2 
3039 N N   . SER A 198 ? 0.16936 0.36251 0.16197 -0.03805 -0.02885 -0.00379 212 SER A N   
3040 C CA  . SER A 198 ? 0.16478 0.33922 0.16492 -0.03553 -0.04768 0.00969  212 SER A CA  
3041 C C   . SER A 198 ? 0.15470 0.32003 0.14011 -0.01777 -0.04559 0.01671  212 SER A C   
3042 O O   . SER A 198 ? 0.17484 0.31081 0.14144 -0.02022 -0.03418 0.00206  212 SER A O   
3043 C CB  . SER A 198 ? 0.17579 0.34249 0.17248 -0.02895 -0.04937 0.01900  212 SER A CB  
3044 O OG  . SER A 198 ? 0.18751 0.34436 0.17643 -0.01315 -0.04846 0.02427  212 SER A OG  
3050 N N   . CYS A 199 ? 0.13970 0.31192 0.14025 -0.01456 -0.04161 -0.00075 213 CYS A N   
3051 C CA  . CYS A 199 ? 0.11015 0.29483 0.13350 -0.01389 -0.04144 -0.00219 213 CYS A CA  
3052 C C   . CYS A 199 ? 0.09973 0.27178 0.15875 -0.00180 -0.02401 -0.00507 213 CYS A C   
3053 O O   . CYS A 199 ? 0.12663 0.27564 0.16233 -0.00175 -0.02544 -0.01275 213 CYS A O   
3054 C CB  . CYS A 199 ? 0.14095 0.30724 0.17108 -0.02249 -0.02545 -0.01231 213 CYS A CB  
3055 S SG  . CYS A 199 ? 0.15794 0.32036 0.19397 -0.02425 -0.06337 -0.02799 213 CYS A SG  
3061 N N   . TYR A 200 ? 0.08706 0.25305 0.13622 -0.00528 -0.03682 -0.00294 214 TYR A N   
3062 C CA  . TYR A 200 ? 0.09589 0.22999 0.14737 -0.00749 -0.03307 -0.00224 214 TYR A CA  
3063 C C   . TYR A 200 ? 0.09450 0.21540 0.14045 -0.00063 -0.04994 -0.01159 214 TYR A C   
3064 O O   . TYR A 200 ? 0.08985 0.22199 0.14247 0.00349  -0.05134 0.00053  214 TYR A O   
3065 C CB  . TYR A 200 ? 0.10517 0.22332 0.14482 -0.01932 -0.03473 -0.00393 214 TYR A CB  
3066 C CG  . TYR A 200 ? 0.11101 0.21281 0.15656 -0.01817 -0.02981 0.01444  214 TYR A CG  
3067 C CD1 . TYR A 200 ? 0.14977 0.21350 0.15334 -0.00363 -0.03233 0.01230  214 TYR A CD1 
3068 C CD2 . TYR A 200 ? 0.13214 0.20500 0.15804 -0.01439 -0.02657 0.02332  214 TYR A CD2 
3069 C CE1 . TYR A 200 ? 0.14382 0.21182 0.18570 -0.01058 -0.04335 0.00400  214 TYR A CE1 
3070 C CE2 . TYR A 200 ? 0.15638 0.20941 0.15487 -0.01309 -0.03011 -0.00249 214 TYR A CE2 
3071 C CZ  . TYR A 200 ? 0.13666 0.21021 0.20803 -0.00656 -0.03228 0.00640  214 TYR A CZ  
3072 O OH  . TYR A 200 ? 0.15759 0.21413 0.28189 0.00046  -0.02853 0.00704  214 TYR A OH  
3082 N N   . PHE A 201 ? 0.08049 0.20301 0.14404 0.00129  -0.04578 -0.01187 215 PHE A N   
3083 C CA  . PHE A 201 ? 0.07539 0.19074 0.13154 0.01027  -0.03971 -0.00705 215 PHE A CA  
3084 C C   . PHE A 201 ? 0.08765 0.18723 0.13047 0.00245  -0.04645 -0.00141 215 PHE A C   
3085 O O   . PHE A 201 ? 0.09484 0.18388 0.14240 0.00283  -0.04087 0.00336  215 PHE A O   
3086 C CB  . PHE A 201 ? 0.08602 0.18744 0.13261 0.01960  -0.03992 -0.00049 215 PHE A CB  
3087 C CG  . PHE A 201 ? 0.10366 0.18944 0.14121 0.01655  -0.04780 -0.01319 215 PHE A CG  
3088 C CD1 . PHE A 201 ? 0.11602 0.19289 0.15049 0.02331  -0.05862 -0.01494 215 PHE A CD1 
3089 C CD2 . PHE A 201 ? 0.12966 0.19237 0.17151 0.01163  -0.03704 -0.01880 215 PHE A CD2 
3090 C CE1 . PHE A 201 ? 0.12847 0.19941 0.17273 0.02005  -0.06658 -0.01042 215 PHE A CE1 
3091 C CE2 . PHE A 201 ? 0.15031 0.20323 0.18295 0.02371  -0.04561 -0.01869 215 PHE A CE2 
3092 C CZ  . PHE A 201 ? 0.15286 0.20392 0.17720 0.01875  -0.06906 -0.02394 215 PHE A CZ  
3102 N N   . LYS A 202 ? 0.07483 0.17876 0.13051 -0.00065 -0.04478 -0.00294 216 LYS A N   
3103 C CA  . LYS A 202 ? 0.07582 0.16536 0.15335 0.00740  -0.04167 0.00119  216 LYS A CA  
3104 C C   . LYS A 202 ? 0.06873 0.15567 0.12985 0.00060  -0.04622 0.00928  216 LYS A C   
3105 O O   . LYS A 202 ? 0.08259 0.15321 0.13608 0.00081  -0.03855 -0.00427 216 LYS A O   
3106 C CB  . LYS A 202 ? 0.09552 0.16038 0.15510 0.01073  -0.04990 0.01010  216 LYS A CB  
3107 C CG  . LYS A 202 ? 0.10931 0.18625 0.17250 0.01481  -0.04107 0.02115  216 LYS A CG  
3108 C CD  . LYS A 202 ? 0.12249 0.19311 0.16347 0.00836  -0.04789 0.02850  216 LYS A CD  
3109 C CE  . LYS A 202 ? 0.15260 0.19228 0.19404 0.01344  -0.03514 0.01181  216 LYS A CE  
3110 N NZ  . LYS A 202 ? 0.16519 0.19341 0.19650 0.02720  -0.04603 0.00861  216 LYS A NZ  
3124 N N   . ALA A 203 ? 0.06981 0.14918 0.14149 0.00527  -0.04932 0.01552  217 ALA A N   
3125 C CA  . ALA A 203 ? 0.08120 0.15300 0.14019 0.01045  -0.04772 0.01133  217 ALA A CA  
3126 C C   . ALA A 203 ? 0.09562 0.14889 0.13396 0.01658  -0.04167 0.01540  217 ALA A C   
3127 O O   . ALA A 203 ? 0.10635 0.16890 0.15391 -0.01632 -0.02984 -0.00009 217 ALA A O   
3128 C CB  . ALA A 203 ? 0.10248 0.16087 0.15225 0.00586  -0.02494 -0.00489 217 ALA A CB  
3134 N N   . GLY A 204 ? 0.08208 0.14620 0.14511 0.00670  -0.04980 0.00422  218 GLY A N   
3135 C CA  . GLY A 204 ? 0.09133 0.15042 0.14600 0.00402  -0.06541 -0.00069 218 GLY A CA  
3136 C C   . GLY A 204 ? 0.08938 0.13618 0.14525 -0.00385 -0.05167 0.01427  218 GLY A C   
3137 O O   . GLY A 204 ? 0.09576 0.14413 0.16196 -0.00895 -0.05364 0.00157  218 GLY A O   
3141 N N   . ALA A 205 ? 0.08396 0.14233 0.17328 0.00693  -0.04892 0.01768  219 ALA A N   
3142 C CA  . ALA A 205 ? 0.09015 0.14968 0.17751 0.00252  -0.05539 0.01308  219 ALA A CA  
3143 C C   . ALA A 205 ? 0.09086 0.15149 0.17025 0.01111  -0.05099 0.01082  219 ALA A C   
3144 O O   . ALA A 205 ? 0.10515 0.16175 0.19965 -0.00245 -0.06036 0.02628  219 ALA A O   
3145 C CB  . ALA A 205 ? 0.10823 0.14991 0.18476 0.00958  -0.03974 -0.00104 219 ALA A CB  
3151 N N   . TYR A 206 ? 0.08824 0.16084 0.17827 0.01547  -0.05346 0.01658  220 TYR A N   
3152 C CA  . TYR A 206 ? 0.09568 0.17287 0.17436 0.02003  -0.05011 0.01918  220 TYR A CA  
3153 C C   . TYR A 206 ? 0.08854 0.17702 0.17857 0.01315  -0.06253 0.01668  220 TYR A C   
3154 O O   . TYR A 206 ? 0.09145 0.17066 0.20929 0.00657  -0.06019 0.01561  220 TYR A O   
3155 C CB  . TYR A 206 ? 0.09845 0.19226 0.18269 0.01771  -0.04505 0.01332  220 TYR A CB  
3156 C CG  . TYR A 206 ? 0.12763 0.20031 0.19381 0.00335  -0.06767 0.00574  220 TYR A CG  
3157 C CD1 . TYR A 206 ? 0.13893 0.20895 0.19831 0.00943  -0.07306 0.01756  220 TYR A CD1 
3158 C CD2 . TYR A 206 ? 0.15696 0.21879 0.19671 -0.01460 -0.07276 0.00477  220 TYR A CD2 
3159 C CE1 . TYR A 206 ? 0.16586 0.23122 0.22357 0.02714  -0.07314 0.01734  220 TYR A CE1 
3160 C CE2 . TYR A 206 ? 0.16413 0.23383 0.20449 0.01051  -0.09577 0.01569  220 TYR A CE2 
3161 C CZ  . TYR A 206 ? 0.18968 0.24963 0.21431 0.02256  -0.09764 0.04244  220 TYR A CZ  
3162 O OH  . TYR A 206 ? 0.24649 0.28602 0.24220 0.01715  -0.10614 0.05378  220 TYR A OH  
3172 N N   . ASN A 207 ? 0.09934 0.17092 0.20659 0.01920  -0.05541 0.01208  221 ASN A N   
3173 C CA  . ASN A 207 ? 0.10288 0.17136 0.22462 0.03270  -0.05923 0.00232  221 ASN A CA  
3174 C C   . ASN A 207 ? 0.10527 0.18191 0.23346 0.02767  -0.06811 0.01339  221 ASN A C   
3175 O O   . ASN A 207 ? 0.12873 0.19344 0.26238 0.02352  -0.06799 0.03306  221 ASN A O   
3176 C CB  . ASN A 207 ? 0.12650 0.17593 0.21728 0.02986  -0.06035 -0.01552 221 ASN A CB  
3177 C CG  . ASN A 207 ? 0.13071 0.18217 0.22973 0.02082  -0.06296 -0.00997 221 ASN A CG  
3178 O OD1 . ASN A 207 ? 0.15035 0.20237 0.27326 0.00210  -0.03609 -0.02933 221 ASN A OD1 
3179 N ND2 . ASN A 207 ? 0.15099 0.18929 0.25574 0.02880  -0.06447 -0.00296 221 ASN A ND2 
3186 N N   . ASN A 208 ? 0.10212 0.18711 0.24374 0.02131  -0.06123 0.01727  222 ASN A N   
3187 C CA  . ASN A 208 ? 0.10334 0.19782 0.25161 0.02075  -0.07142 0.01029  222 ASN A CA  
3188 C C   . ASN A 208 ? 0.10869 0.21302 0.25902 0.03007  -0.07243 0.01031  222 ASN A C   
3189 O O   . ASN A 208 ? 0.10823 0.21296 0.29795 0.03440  -0.04359 0.01754  222 ASN A O   
3190 C CB  . ASN A 208 ? 0.11258 0.20442 0.26133 0.02964  -0.07614 0.00663  222 ASN A CB  
3191 C CG  . ASN A 208 ? 0.12804 0.20622 0.25295 0.02220  -0.08092 0.00686  222 ASN A CG  
3192 O OD1 . ASN A 208 ? 0.12807 0.20101 0.24240 0.02141  -0.07376 -0.00575 222 ASN A OD1 
3193 N ND2 . ASN A 208 ? 0.14699 0.21733 0.28499 0.03179  -0.06072 0.00837  222 ASN A ND2 
3200 N N   . ASN A 209 ? 0.11939 0.22514 0.26405 0.03525  -0.08058 0.00498  223 ASN A N   
3201 C CA  . ASN A 209 ? 0.13262 0.24322 0.30919 0.04906  -0.08255 0.00072  223 ASN A CA  
3202 C C   . ASN A 209 ? 0.13290 0.23902 0.31607 0.05955  -0.06080 0.00840  223 ASN A C   
3203 O O   . ASN A 209 ? 0.14111 0.25408 0.33425 0.05707  -0.04853 0.00094  223 ASN A O   
3204 C CB  . ASN A 209 ? 0.14748 0.27480 0.36571 0.04579  -0.09639 -0.01210 223 ASN A CB  
3205 C CG  . ASN A 209 ? 0.18586 0.30255 0.39572 0.03649  -0.12708 -0.01883 223 ASN A CG  
3206 O OD1 . ASN A 209 ? 0.23916 0.32345 0.40278 0.02009  -0.11324 -0.02440 223 ASN A OD1 
3207 N ND2 . ASN A 209 ? 0.21228 0.31905 0.42626 0.03805  -0.11951 -0.02243 223 ASN A ND2 
3214 N N   . PRO A 210 ? 0.12032 0.22059 0.29847 0.05685  -0.05974 0.00305  224 PRO A N   
3215 C CA  . PRO A 210 ? 0.12711 0.23146 0.31196 0.06547  -0.05836 -0.00198 224 PRO A CA  
3216 C C   . PRO A 210 ? 0.14256 0.25358 0.33088 0.07269  -0.06913 0.00231  224 PRO A C   
3217 O O   . PRO A 210 ? 0.15613 0.25340 0.34940 0.07549  -0.06571 0.00392  224 PRO A O   
3218 C CB  . PRO A 210 ? 0.13331 0.22359 0.28120 0.05741  -0.07578 0.00932  224 PRO A CB  
3219 C CG  . PRO A 210 ? 0.15273 0.20627 0.27581 0.06135  -0.06251 0.01966  224 PRO A CG  
3220 C CD  . PRO A 210 ? 0.13608 0.21399 0.29432 0.04438  -0.06947 -0.00403 224 PRO A CD  
3228 N N   . THR A 211 ? 0.14947 0.27987 0.38254 0.08383  -0.04802 -0.00339 225 THR A N   
3229 C CA  . THR A 211 ? 0.16524 0.29893 0.40159 0.09760  -0.05438 -0.00538 225 THR A CA  
3230 C C   . THR A 211 ? 0.19058 0.30030 0.40524 0.10099  -0.04198 -0.03428 225 THR A C   
3231 O O   . THR A 211 ? 0.20651 0.30933 0.44078 0.11279  -0.02656 -0.05159 225 THR A O   
3232 C CB  . THR A 211 ? 0.18703 0.32838 0.43791 0.08934  -0.03233 0.00515  225 THR A CB  
3233 O OG1 . THR A 211 ? 0.21122 0.34822 0.45145 0.08345  -0.00506 0.00947  225 THR A OG1 
3234 C CG2 . THR A 211 ? 0.17991 0.32890 0.44908 0.08854  -0.04073 0.00435  225 THR A CG2 
3242 N N   . SER A 212 ? 0.19221 0.29804 0.38752 0.09612  -0.05273 -0.03054 226 SER A N   
3243 C CA  . SER A 212 ? 0.22303 0.29509 0.39300 0.07903  -0.02905 -0.03844 226 SER A CA  
3244 C C   . SER A 212 ? 0.21473 0.26901 0.37435 0.09156  -0.03899 -0.03984 226 SER A C   
3245 O O   . SER A 212 ? 0.21168 0.25913 0.38144 0.08998  -0.04098 -0.04438 226 SER A O   
3246 C CB  . SER A 212 ? 0.26632 0.31366 0.41027 0.05042  -0.00850 -0.05382 226 SER A CB  
3247 O OG  . SER A 212 ? 0.29675 0.33376 0.41444 0.03661  -0.00507 -0.05423 226 SER A OG  
3253 N N   . GLU A 213 ? 0.22787 0.25188 0.36508 0.11078  -0.05495 -0.01816 227 GLU A N   
3254 C CA  . GLU A 213 ? 0.25329 0.24677 0.37368 0.10346  -0.05066 -0.01806 227 GLU A CA  
3255 C C   . GLU A 213 ? 0.26220 0.24532 0.36767 0.09363  -0.04249 -0.02104 227 GLU A C   
3256 O O   . GLU A 213 ? 0.25741 0.25230 0.36751 0.07314  -0.04417 -0.02101 227 GLU A O   
3257 C CB  . GLU A 213 ? 0.27451 0.26090 0.39766 0.08250  -0.05244 -0.00987 227 GLU A CB  
3258 C CG  . GLU A 213 ? 0.27854 0.27107 0.39825 0.07869  -0.06064 -0.00954 227 GLU A CG  
3259 C CD  . GLU A 213 ? 0.28492 0.28440 0.41937 0.07778  -0.07497 -0.00568 227 GLU A CD  
3260 O OE1 . GLU A 213 ? 0.27217 0.27326 0.41530 0.10098  -0.11130 0.01107  227 GLU A OE1 
3261 O OE2 . GLU A 213 ? 0.30962 0.30806 0.45976 0.05344  -0.04193 -0.01612 227 GLU A OE2 
3268 N N   . SER A 214 ? 0.27047 0.24361 0.37386 0.09090  -0.03801 -0.02686 228 SER A N   
3269 C CA  . SER A 214 ? 0.27759 0.25286 0.36358 0.08510  -0.04722 -0.03171 228 SER A CA  
3270 C C   . SER A 214 ? 0.25706 0.24814 0.34622 0.07935  -0.03779 -0.03954 228 SER A C   
3271 O O   . SER A 214 ? 0.28398 0.25929 0.35138 0.05642  -0.03548 -0.05161 228 SER A O   
3272 C CB  . SER A 214 ? 0.31617 0.26689 0.39281 0.07821  -0.03128 -0.03679 228 SER A CB  
3273 O OG  . SER A 214 ? 0.33095 0.28507 0.41998 0.07599  -0.02645 -0.05145 228 SER A OG  
3279 N N   . ALA A 215 ? 0.21234 0.23790 0.33166 0.07754  -0.03620 -0.02369 229 ALA A N   
3280 C CA  . ALA A 215 ? 0.18526 0.23431 0.31283 0.06403  -0.03528 -0.01572 229 ALA A CA  
3281 C C   . ALA A 215 ? 0.17680 0.22615 0.27392 0.04055  -0.02780 -0.01112 229 ALA A C   
3282 O O   . ALA A 215 ? 0.17369 0.24107 0.26881 0.04843  -0.03146 0.00144  229 ALA A O   
3283 C CB  . ALA A 215 ? 0.18401 0.24173 0.34698 0.07226  -0.01578 -0.02553 229 ALA A CB  
3289 N N   . THR A 216 ? 0.18228 0.20690 0.25265 0.03348  -0.01934 -0.02460 230 THR A N   
3290 C CA  . THR A 216 ? 0.17466 0.19702 0.23863 0.03729  -0.03271 -0.02763 230 THR A CA  
3291 C C   . THR A 216 ? 0.17095 0.18731 0.21888 0.02629  -0.02968 -0.01473 230 THR A C   
3292 O O   . THR A 216 ? 0.20927 0.19675 0.22529 0.02720  -0.03559 -0.01490 230 THR A O   
3293 C CB  . THR A 216 ? 0.18187 0.20577 0.24501 0.03774  -0.05815 -0.03404 230 THR A CB  
3294 O OG1 . THR A 216 ? 0.23793 0.21281 0.28008 0.03230  -0.02518 -0.04657 230 THR A OG1 
3295 C CG2 . THR A 216 ? 0.17089 0.21808 0.25836 0.02485  -0.06703 -0.04236 230 THR A CG2 
3303 N N   . ALA A 217 ? 0.13913 0.17804 0.20924 0.01964  -0.03724 -0.02075 231 ALA A N   
3304 C CA  . ALA A 217 ? 0.12199 0.17121 0.20100 0.01974  -0.03922 -0.01375 231 ALA A CA  
3305 C C   . ALA A 217 ? 0.12407 0.16614 0.19733 0.00941  -0.03541 -0.01255 231 ALA A C   
3306 O O   . ALA A 217 ? 0.12152 0.16852 0.21581 0.01472  -0.03409 0.01276  231 ALA A O   
3307 C CB  . ALA A 217 ? 0.12801 0.17590 0.21232 -0.00092 -0.05656 -0.00654 231 ALA A CB  
3313 N N   . ARG A 218 ? 0.10435 0.16699 0.18827 0.00756  -0.03718 -0.00777 232 ARG A N   
3314 C CA  . ARG A 218 ? 0.10877 0.16466 0.18057 0.01126  -0.02821 -0.01373 232 ARG A CA  
3315 C C   . ARG A 218 ? 0.11034 0.15492 0.16360 -0.00027 -0.02749 -0.00574 232 ARG A C   
3316 O O   . ARG A 218 ? 0.12014 0.16410 0.18989 0.00331  -0.01795 -0.00190 232 ARG A O   
3317 C CB  . ARG A 218 ? 0.12493 0.17609 0.19481 0.01354  -0.02682 -0.01088 232 ARG A CB  
3318 C CG  . ARG A 218 ? 0.12830 0.19449 0.18467 0.00447  -0.03972 -0.01381 232 ARG A CG  
3319 C CD  . ARG A 218 ? 0.16497 0.20861 0.19804 0.00695  -0.03992 -0.02872 232 ARG A CD  
3320 N NE  . ARG A 218 ? 0.18162 0.23200 0.19753 0.01244  -0.02809 -0.04435 232 ARG A NE  
3321 C CZ  . ARG A 218 ? 0.18322 0.24642 0.18227 -0.00041 -0.02246 -0.03447 232 ARG A CZ  
3322 N NH1 . ARG A 218 ? 0.17145 0.24001 0.18004 0.00592  -0.05164 -0.02329 232 ARG A NH1 
3323 N NH2 . ARG A 218 ? 0.18967 0.27230 0.19792 -0.00581 -0.00883 -0.03403 232 ARG A NH2 
3337 N N   . ILE A 219 ? 0.09461 0.15374 0.15735 -0.00185 -0.04701 -0.00582 233 ILE A N   
3338 C CA  . ILE A 219 ? 0.09096 0.15362 0.15528 -0.00420 -0.04599 -0.00158 233 ILE A CA  
3339 C C   . ILE A 219 ? 0.09466 0.15473 0.15141 -0.00070 -0.05974 -0.00630 233 ILE A C   
3340 O O   . ILE A 219 ? 0.09330 0.16136 0.17802 -0.00652 -0.05852 0.00321  233 ILE A O   
3341 C CB  . ILE A 219 ? 0.08874 0.16486 0.15393 0.00168  -0.06286 0.00077  233 ILE A CB  
3342 C CG1 . ILE A 219 ? 0.09946 0.16949 0.17276 0.00338  -0.05257 -0.00594 233 ILE A CG1 
3343 C CG2 . ILE A 219 ? 0.09893 0.16328 0.16225 0.00888  -0.05136 -0.00584 233 ILE A CG2 
3344 C CD1 . ILE A 219 ? 0.08855 0.18362 0.17966 0.01117  -0.04462 0.00968  233 ILE A CD1 
3356 N N   . LYS A 220 ? 0.08770 0.15372 0.15099 -0.00505 -0.05578 -0.00651 234 LYS A N   
3357 C CA  . LYS A 220 ? 0.09158 0.15777 0.18772 0.00673  -0.06758 -0.01339 234 LYS A CA  
3358 C C   . LYS A 220 ? 0.10084 0.14844 0.17817 0.00361  -0.05444 0.00455  234 LYS A C   
3359 O O   . LYS A 220 ? 0.13951 0.15767 0.22384 -0.02003 -0.00135 -0.02244 234 LYS A O   
3360 C CB  . LYS A 220 ? 0.10860 0.17039 0.19994 0.00853  -0.07302 -0.00497 234 LYS A CB  
3361 C CG  . LYS A 220 ? 0.14157 0.19559 0.19185 -0.00242 -0.05157 0.00738  234 LYS A CG  
3362 C CD  . LYS A 220 ? 0.15242 0.21952 0.18875 -0.01117 -0.06241 0.01109  234 LYS A CD  
3363 C CE  . LYS A 220 ? 0.15649 0.23163 0.19241 -0.02562 -0.03721 0.00482  234 LYS A CE  
3364 N NZ  . LYS A 220 ? 0.16311 0.23846 0.17157 -0.02132 -0.05930 -0.00122 234 LYS A NZ  
3378 N N   . PHE A 221 ? 0.09273 0.14225 0.14466 -0.00865 -0.05692 0.00328  235 PHE A N   
3379 C CA  . PHE A 221 ? 0.08870 0.15462 0.15042 -0.00358 -0.05915 -0.00603 235 PHE A CA  
3380 C C   . PHE A 221 ? 0.08740 0.16121 0.15835 -0.00136 -0.06437 -0.00176 235 PHE A C   
3381 O O   . PHE A 221 ? 0.10741 0.16436 0.17884 0.00047  -0.07771 0.00573  235 PHE A O   
3382 C CB  . PHE A 221 ? 0.07829 0.15753 0.16434 0.00137  -0.05838 -0.00335 235 PHE A CB  
3383 C CG  . PHE A 221 ? 0.07225 0.16128 0.16230 -0.00466 -0.05335 0.00174  235 PHE A CG  
3384 C CD1 . PHE A 221 ? 0.08603 0.16635 0.16211 0.00626  -0.03735 0.01055  235 PHE A CD1 
3385 C CD2 . PHE A 221 ? 0.09459 0.16852 0.15605 0.00436  -0.06768 0.00906  235 PHE A CD2 
3386 C CE1 . PHE A 221 ? 0.09252 0.17451 0.17119 0.00332  -0.04513 0.01464  235 PHE A CE1 
3387 C CE2 . PHE A 221 ? 0.08684 0.17470 0.14672 0.00841  -0.04573 0.01050  235 PHE A CE2 
3388 C CZ  . PHE A 221 ? 0.08460 0.18378 0.15290 -0.00356 -0.04882 0.02245  235 PHE A CZ  
3398 N N   . ALA A 222 ? 0.09936 0.15887 0.16375 0.00860  -0.06219 0.00875  236 ALA A N   
3399 C CA  . ALA A 222 ? 0.11289 0.15873 0.14318 0.00127  -0.06970 0.00127  236 ALA A CA  
3400 C C   . ALA A 222 ? 0.09862 0.15614 0.16966 -0.00352 -0.07158 0.00976  236 ALA A C   
3401 O O   . ALA A 222 ? 0.11026 0.17053 0.17162 0.00269  -0.07800 0.00954  236 ALA A O   
3402 C CB  . ALA A 222 ? 0.15052 0.16612 0.14659 -0.00962 -0.05918 0.01016  236 ALA A CB  
3408 N N   . ALA A 223 ? 0.11083 0.15558 0.16063 0.00574  -0.07644 -0.00137 237 ALA A N   
3409 C CA  . ALA A 223 ? 0.10794 0.16005 0.16469 -0.00151 -0.07371 0.00054  237 ALA A CA  
3410 C C   . ALA A 223 ? 0.09436 0.15547 0.14215 -0.00886 -0.06535 -0.00905 237 ALA A C   
3411 O O   . ALA A 223 ? 0.07978 0.16320 0.15155 -0.00638 -0.05874 0.00224  237 ALA A O   
3412 C CB  . ALA A 223 ? 0.11745 0.15721 0.17735 0.00548  -0.06429 0.00661  237 ALA A CB  
3418 N N   . LEU A 224 ? 0.08398 0.18187 0.15361 0.00702  -0.06084 -0.00142 238 LEU A N   
3419 C CA  . LEU A 224 ? 0.07473 0.17349 0.15937 0.00216  -0.05372 0.00329  238 LEU A CA  
3420 C C   . LEU A 224 ? 0.07966 0.19102 0.16227 -0.00010 -0.05931 -0.00083 238 LEU A C   
3421 O O   . LEU A 224 ? 0.07160 0.19960 0.17975 -0.00686 -0.05185 -0.00266 238 LEU A O   
3422 C CB  . LEU A 224 ? 0.07542 0.17273 0.17089 -0.00715 -0.05537 0.00536  238 LEU A CB  
3423 C CG  . LEU A 224 ? 0.08191 0.18435 0.16181 0.00572  -0.06000 0.00815  238 LEU A CG  
3424 C CD1 . LEU A 224 ? 0.08418 0.19091 0.16866 -0.00493 -0.06219 0.00338  238 LEU A CD1 
3425 C CD2 . LEU A 224 ? 0.09548 0.18819 0.16835 0.01342  -0.05377 0.00922  238 LEU A CD2 
3437 N N   . ALA A 225 ? 0.09005 0.20063 0.16486 -0.00704 -0.05145 -0.01379 239 ALA A N   
3438 C CA  . ALA A 225 ? 0.09280 0.21597 0.17295 0.00419  -0.05883 -0.01811 239 ALA A CA  
3439 C C   . ALA A 225 ? 0.08916 0.22895 0.17754 0.00593  -0.05450 -0.02456 239 ALA A C   
3440 O O   . ALA A 225 ? 0.09472 0.23284 0.18434 -0.01614 -0.05148 -0.01343 239 ALA A O   
3441 C CB  . ALA A 225 ? 0.10673 0.23119 0.18754 0.03039  -0.05209 -0.02097 239 ALA A CB  
3447 N N   A TRP A 226 ? 0.08813 0.22311 0.18896 0.01227  -0.05488 -0.02887 240 TRP A N   
3448 N N   B TRP A 226 ? 0.11892 0.26134 0.21017 0.00116  -0.04386 -0.04592 240 TRP A N   
3449 C CA  A TRP A 226 ? 0.11021 0.24555 0.20858 0.01958  -0.05693 -0.03563 240 TRP A CA  
3450 C CA  B TRP A 226 ? 0.14966 0.29539 0.24210 -0.00187 -0.03496 -0.06684 240 TRP A CA  
3451 C C   A TRP A 226 ? 0.12388 0.30560 0.26674 0.00277  -0.06944 -0.07181 240 TRP A C   
3452 C C   B TRP A 226 ? 0.15723 0.32520 0.30137 -0.00398 -0.04282 -0.09723 240 TRP A C   
3453 O O   A TRP A 226 ? 0.13750 0.32500 0.27901 -0.03333 -0.01227 -0.08325 240 TRP A O   
3454 O O   B TRP A 226 ? 0.16323 0.32729 0.30945 -0.00681 -0.03419 -0.09802 240 TRP A O   
3455 C CB  A TRP A 226 ? 0.16097 0.24087 0.24039 0.03175  -0.02876 -0.01407 240 TRP A CB  
3456 C CB  B TRP A 226 ? 0.16905 0.30016 0.21470 -0.00584 -0.02365 -0.05865 240 TRP A CB  
3457 C CG  A TRP A 226 ? 0.13780 0.24525 0.20610 0.01106  -0.05505 -0.01810 240 TRP A CG  
3458 C CG  B TRP A 226 ? 0.18172 0.30319 0.17349 -0.01006 -0.02172 -0.05138 240 TRP A CG  
3459 C CD1 A TRP A 226 ? 0.12844 0.24084 0.20401 0.02639  -0.03533 -0.00643 240 TRP A CD1 
3460 C CD1 B TRP A 226 ? 0.18200 0.30306 0.14142 -0.01230 -0.02478 -0.04493 240 TRP A CD1 
3461 C CD2 A TRP A 226 ? 0.10053 0.22948 0.17615 0.01452  -0.06874 -0.00362 240 TRP A CD2 
3462 C CD2 B TRP A 226 ? 0.18566 0.30556 0.16982 -0.01002 -0.01254 -0.04839 240 TRP A CD2 
3463 N NE1 A TRP A 226 ? 0.11790 0.23882 0.20281 -0.00614 -0.05134 -0.00718 240 TRP A NE1 
3464 N NE1 B TRP A 226 ? 0.18472 0.30431 0.14241 -0.00502 -0.00845 -0.04131 240 TRP A NE1 
3465 C CE2 A TRP A 226 ? 0.10489 0.22387 0.14872 0.00888  -0.06522 -0.01322 240 TRP A CE2 
3466 C CE2 B TRP A 226 ? 0.18837 0.30591 0.16107 -0.00893 -0.01147 -0.04654 240 TRP A CE2 
3467 C CE3 A TRP A 226 ? 0.11557 0.24820 0.16458 0.02671  -0.06892 0.00043  240 TRP A CE3 
3468 C CE3 B TRP A 226 ? 0.19200 0.30729 0.17619 -0.01138 -0.00618 -0.04948 240 TRP A CE3 
3469 C CZ2 A TRP A 226 ? 0.11721 0.22990 0.17025 0.02565  -0.06119 -0.00499 240 TRP A CZ2 
3470 C CZ2 B TRP A 226 ? 0.19003 0.30756 0.18015 -0.00900 -0.00111 -0.04661 240 TRP A CZ2 
3471 C CZ3 A TRP A 226 ? 0.10337 0.25694 0.15735 0.01150  -0.05838 -0.01720 240 TRP A CZ3 
3472 C CZ3 B TRP A 226 ? 0.19374 0.30775 0.17536 -0.00975 -0.00418 -0.05105 240 TRP A CZ3 
3473 C CH2 A TRP A 226 ? 0.13139 0.24354 0.16606 0.03098  -0.07596 -0.03055 240 TRP A CH2 
3474 C CH2 B TRP A 226 ? 0.19298 0.30801 0.18207 -0.00890 0.00177  -0.04774 240 TRP A CH2 
3495 N N   . VAL A 227 ? 0.15922 0.35107 0.35081 -0.00609 -0.05908 -0.12800 241 VAL A N   
3496 C CA  A VAL A 227 ? 0.20874 0.38507 0.41303 -0.01017 -0.05680 -0.15455 241 VAL A CA  
3497 C CA  B VAL A 227 ? 0.20686 0.38497 0.41358 -0.00421 -0.04023 -0.15508 241 VAL A CA  
3498 C C   . VAL A 227 ? 0.23044 0.41439 0.45698 -0.00838 -0.04178 -0.16801 241 VAL A C   
3499 O O   . VAL A 227 ? 0.17422 0.41933 0.45936 -0.00959 -0.07851 -0.13456 241 VAL A O   
3500 C CB  A VAL A 227 ? 0.24004 0.39161 0.45085 -0.00277 -0.06738 -0.14281 241 VAL A CB  
3501 C CB  B VAL A 227 ? 0.22919 0.38962 0.44010 0.00693  -0.02338 -0.15906 241 VAL A CB  
3502 C CG1 A VAL A 227 ? 0.26174 0.40028 0.46763 0.00326  -0.06101 -0.12624 241 VAL A CG1 
3503 C CG1 B VAL A 227 ? 0.22831 0.38971 0.43557 0.01050  -0.02184 -0.17013 241 VAL A CG1 
3504 C CG2 A VAL A 227 ? 0.24110 0.39137 0.45678 -0.00419 -0.07459 -0.14129 241 VAL A CG2 
3505 C CG2 B VAL A 227 ? 0.24389 0.39508 0.45629 0.01061  -0.00958 -0.14943 241 VAL A CG2 
3522 N N   . ASP A 228 ? 0.38626 0.46711 0.60187 0.01984  0.08678  -0.16733 242 ASP A N   
3523 C CA  . ASP A 228 ? 0.54642 0.51954 0.75401 0.04210  0.19944  -0.15580 242 ASP A CA  
3524 C C   . ASP A 228 ? 0.60966 0.55052 0.85072 0.06976  0.23140  -0.14399 242 ASP A C   
3525 O O   . ASP A 228 ? 0.62179 0.55780 0.85671 0.06787  0.22388  -0.13819 242 ASP A O   
3526 C CB  . ASP A 228 ? 0.63195 0.53927 0.80606 0.03438  0.27482  -0.14966 242 ASP A CB  
3527 C CG  . ASP A 228 ? 0.70303 0.55559 0.85151 0.02914  0.33937  -0.14438 242 ASP A CG  
3528 O OD1 . ASP A 228 ? 0.72673 0.56039 0.86697 0.03210  0.36769  -0.14159 242 ASP A OD1 
3529 O OD2 . ASP A 228 ? 0.73810 0.56175 0.87082 0.02215  0.35258  -0.14342 242 ASP A OD2 
3534 N N   . HIS A 229 ? 0.65716 0.57188 0.93590 0.09061  0.26046  -0.13548 243 HIS A N   
3535 C CA  . HIS A 229 ? 0.69840 0.59277 1.01013 0.10046  0.27615  -0.12695 243 HIS A CA  
3536 C C   . HIS A 229 ? 0.71778 0.60144 1.03599 0.10613  0.29455  -0.12537 243 HIS A C   
3537 O O   . HIS A 229 ? 0.72815 0.60590 1.04866 0.10813  0.30459  -0.12726 243 HIS A O   
3538 C CB  . HIS A 229 ? 0.70973 0.60167 1.04394 0.10086  0.26921  -0.12505 243 HIS A CB  
3539 C CG  . HIS A 229 ? 0.72382 0.60975 1.07164 0.10110  0.26260  -0.12293 243 HIS A CG  
3540 N ND1 . HIS A 229 ? 0.73039 0.61414 1.08364 0.09945  0.26088  -0.12150 243 HIS A ND1 
3541 C CD2 . HIS A 229 ? 0.73239 0.61352 1.08160 0.09888  0.25914  -0.12298 243 HIS A CD2 
3542 C CE1 . HIS A 229 ? 0.73450 0.61514 1.08824 0.09929  0.25928  -0.12202 243 HIS A CE1 
3543 N NE2 . HIS A 229 ? 0.73147 0.61380 1.08608 0.10115  0.25972  -0.12392 243 HIS A NE2 
3551 C C1  . BEM B .   ? 0.72631 0.44352 0.85565 0.00520  0.14531  0.06125  1   BEM B C1  
3552 C C2  . BEM B .   ? 0.71457 0.44245 0.83641 0.00617  0.14092  0.06127  1   BEM B C2  
3553 O O2  . BEM B .   ? 0.73175 0.44973 0.84944 0.00709  0.14944  0.05939  1   BEM B O2  
3554 C C3  . BEM B .   ? 0.67326 0.42975 0.78945 0.00845  0.12526  0.06547  1   BEM B C3  
3555 O O3  . BEM B .   ? 0.68752 0.44140 0.81219 0.01155  0.12980  0.06268  1   BEM B O3  
3556 C C4  . BEM B .   ? 0.61468 0.40318 0.70914 0.00789  0.10055  0.06927  1   BEM B C4  
3557 O O4  . BEM B .   ? 0.47772 0.35144 0.51041 -0.00381 0.03417  0.07570  1   BEM B O4  
3558 C C5  . BEM B .   ? 0.68816 0.43313 0.82335 0.01697  0.14248  0.06420  1   BEM B C5  
3559 O O5  . BEM B .   ? 0.71283 0.44056 0.84889 0.01341  0.14587  0.06418  1   BEM B O5  
3560 C C6  . BEM B .   ? 0.72945 0.45356 0.89606 0.02711  0.17245  0.06264  1   BEM B C6  
3561 O O6B . BEM B .   ? 0.74450 0.45924 0.92252 0.02912  0.18352  0.06072  1   BEM B O6B 
3562 O O6A . BEM B .   ? 0.74253 0.46260 0.91875 0.03234  0.18149  0.06323  1   BEM B O6A 
3563 O O1  . BEM B .   ? 0.73716 0.44180 0.86470 -0.00196 0.14654  0.06442  1   BEM B O1  
3572 C C1  . LGU B .   ? 0.35240 0.30763 0.35610 -0.00193 -0.03868 0.06399  2   LGU B C1  
3573 C C2  . LGU B .   ? 0.31717 0.29019 0.31590 0.00419  -0.04601 0.07140  2   LGU B C2  
3574 O O2  . LGU B .   ? 0.33351 0.28624 0.35844 0.01167  -0.03291 0.06801  2   LGU B O2  
3575 C C3  . LGU B .   ? 0.27277 0.28190 0.26803 0.00199  -0.05998 0.07979  2   LGU B C3  
3576 O O3  . LGU B .   ? 0.28815 0.28503 0.29568 0.01728  -0.05973 0.10825  2   LGU B O3  
3577 C C4  . LGU B .   ? 0.21534 0.27386 0.21144 -0.00388 -0.07568 0.06306  2   LGU B C4  
3578 O O4  . LGU B .   ? 0.17885 0.26950 0.21368 -0.00481 -0.07187 0.04001  2   LGU B O4  
3579 C C5  . LGU B .   ? 0.22122 0.27537 0.22147 -0.00761 -0.08860 0.04727  2   LGU B C5  
3580 O O5  . LGU B .   ? 0.26115 0.28918 0.25267 -0.00651 -0.09919 0.04512  2   LGU B O5  
3581 C C6  . LGU B .   ? 0.19298 0.26844 0.20392 -0.00123 -0.07095 0.02902  2   LGU B C6  
3582 O O6B . LGU B .   ? 0.18940 0.27366 0.21703 -0.01031 -0.08040 0.01267  2   LGU B O6B 
3583 O O6A . LGU B .   ? 0.18155 0.25981 0.21472 -0.00005 -0.06990 0.03194  2   LGU B O6A 
3591 C C1  . BEM B .   ? 0.18147 0.27402 0.20961 -0.00233 -0.07977 0.01153  3   BEM B C1  
3592 C C2  . BEM B .   ? 0.17426 0.26722 0.21353 0.00114  -0.08438 0.01281  3   BEM B C2  
3593 O O2  . BEM B .   ? 0.17352 0.26352 0.22988 -0.00403 -0.08232 0.02640  3   BEM B O2  
3594 C C3  . BEM B .   ? 0.17459 0.27925 0.22816 0.00338  -0.07683 0.01498  3   BEM B C3  
3595 O O3  . BEM B .   ? 0.17099 0.27421 0.23357 -0.00493 -0.07290 0.02024  3   BEM B O3  
3596 C C4  . BEM B .   ? 0.17561 0.30200 0.25996 0.00663  -0.10630 0.00892  3   BEM B C4  
3597 O O4  . BEM B .   ? 0.19302 0.31443 0.27781 0.00170  -0.12255 -0.00853 3   BEM B O4  
3598 C C5  . BEM B .   ? 0.19744 0.31023 0.25897 0.00902  -0.11383 0.01950  3   BEM B C5  
3599 O O5  . BEM B .   ? 0.18730 0.28925 0.22876 0.00432  -0.10057 0.02294  3   BEM B O5  
3600 C C6  . BEM B .   ? 0.25426 0.33804 0.29775 0.02758  -0.13058 0.04261  3   BEM B C6  
3601 O O6B . BEM B .   ? 0.31299 0.36989 0.35803 0.04001  -0.10195 0.05221  3   BEM B O6B 
3602 O O6A . BEM B .   ? 0.26181 0.33794 0.34442 0.02973  -0.12011 0.03434  3   BEM B O6A 
3610 C C1  . BEM B .   ? 0.21305 0.30568 0.28378 0.00523  -0.12806 0.03235  4   BEM B C1  
3611 C C2  . BEM B .   ? 0.25160 0.31661 0.30114 0.00738  -0.15012 0.06772  4   BEM B C2  
3612 O O2  . BEM B .   ? 0.28207 0.33368 0.33395 -0.00162 -0.14882 0.08773  4   BEM B O2  
3613 C C3  . BEM B .   ? 0.26412 0.31735 0.33660 0.00787  -0.13637 0.05107  4   BEM B C3  
3614 O O3  . BEM B .   ? 0.29091 0.33899 0.39866 -0.01623 -0.10454 0.02075  4   BEM B O3  
3615 C C4  . BEM B .   ? 0.24182 0.30193 0.32426 0.00674  -0.16021 0.03695  4   BEM B C4  
3616 O O4  . BEM B .   ? 0.24347 0.30504 0.35665 0.00025  -0.12713 0.00702  4   BEM B O4  
3617 C C5  . BEM B .   ? 0.22455 0.28523 0.29309 0.00218  -0.14877 0.02894  4   BEM B C5  
3618 O O5  . BEM B .   ? 0.21656 0.28465 0.26290 -0.00228 -0.10837 0.02821  4   BEM B O5  
3619 C C6  . BEM B .   ? 0.21203 0.26064 0.30127 -0.00031 -0.14561 0.00338  4   BEM B C6  
3620 O O6B . BEM B .   ? 0.20499 0.24991 0.32174 -0.00006 -0.13942 0.00418  4   BEM B O6B 
3621 O O6A . BEM B .   ? 0.21139 0.24592 0.32772 0.00896  -0.15019 -0.00974 4   BEM B O6A 
3629 C C1  . BEM B .   ? 0.24129 0.30766 0.36771 0.00439  -0.11770 -0.00656 5   BEM B C1  
3630 C C2  . BEM B .   ? 0.25553 0.31515 0.40458 0.01756  -0.10995 -0.00910 5   BEM B C2  
3631 O O2  . BEM B .   ? 0.28936 0.32371 0.44787 0.03532  -0.08524 0.00886  5   BEM B O2  
3632 C C3  . BEM B .   ? 0.23847 0.32699 0.39952 0.01815  -0.12420 -0.03098 5   BEM B C3  
3633 O O3  . BEM B .   ? 0.24190 0.34184 0.42543 0.01592  -0.10349 -0.03506 5   BEM B O3  
3634 C C4  . BEM B .   ? 0.22556 0.33170 0.38693 0.02057  -0.15386 -0.03149 5   BEM B C4  
3635 O O4  . BEM B .   ? 0.23532 0.35653 0.43696 0.02545  -0.17158 -0.04140 5   BEM B O4  
3636 C C5  . BEM B .   ? 0.22076 0.31856 0.33754 0.01648  -0.14596 -0.00823 5   BEM B C5  
3637 O O5  . BEM B .   ? 0.23015 0.30808 0.34775 0.00757  -0.12062 -0.00708 5   BEM B O5  
3638 C C6  . BEM B .   ? 0.23554 0.31750 0.29102 0.02253  -0.15349 0.00487  5   BEM B C6  
3639 O O6B . BEM B .   ? 0.24160 0.30757 0.26720 0.02227  -0.13903 -0.00914 5   BEM B O6B 
3640 O O6A . BEM B .   ? 0.25793 0.31845 0.30734 0.02762  -0.12976 0.02200  5   BEM B O6A 
3648 C C1  . BEM B .   ? 0.27882 0.38801 0.49270 0.03937  -0.16637 -0.07000 6   BEM B C1  
3649 C C2  . BEM B .   ? 0.28218 0.39526 0.50634 0.02866  -0.19286 -0.09474 6   BEM B C2  
3650 O O2  . BEM B .   ? 0.28671 0.38494 0.52845 0.02625  -0.18791 -0.08287 6   BEM B O2  
3651 C C3  . BEM B .   ? 0.29940 0.41283 0.55931 0.03127  -0.14959 -0.10979 6   BEM B C3  
3652 O O3  . BEM B .   ? 0.30100 0.41537 0.57881 0.01888  -0.12166 -0.12742 6   BEM B O3  
3653 C C4  . BEM B .   ? 0.32916 0.42731 0.59234 0.04831  -0.12507 -0.09775 6   BEM B C4  
3654 O O4  . BEM B .   ? 0.32724 0.43503 0.59639 0.04789  -0.14247 -0.09393 6   BEM B O4  
3655 C C5  . BEM B .   ? 0.36564 0.43285 0.60431 0.05818  -0.08749 -0.09015 6   BEM B C5  
3656 O O5  . BEM B .   ? 0.31227 0.40999 0.54493 0.05679  -0.13758 -0.07531 6   BEM B O5  
3657 C C6  . BEM B .   ? 0.46103 0.45666 0.66714 0.06392  0.00090  -0.09305 6   BEM B C6  
3658 O O6B . BEM B .   ? 0.48892 0.46545 0.68893 0.06562  0.02737  -0.08998 6   BEM B O6B 
3659 O O6A . BEM B .   ? 0.49442 0.46647 0.68105 0.06955  0.02232  -0.09319 6   BEM B O6A 
3668 C C1  . BEM C .   ? 0.44522 0.34479 0.25922 -0.10187 -0.06824 0.04116  1   BEM C C1  
3669 C C2  . BEM C .   ? 0.38337 0.33165 0.22576 -0.10386 -0.08395 0.03237  1   BEM C C2  
3670 O O2  . BEM C .   ? 0.36241 0.33403 0.25053 -0.10911 -0.06073 0.02950  1   BEM C O2  
3671 C C3  . BEM C .   ? 0.34478 0.32178 0.18204 -0.09963 -0.09396 0.02373  1   BEM C C3  
3672 O O3  . BEM C .   ? 0.30987 0.30855 0.17873 -0.09744 -0.07919 0.03323  1   BEM C O3  
3673 C C4  . BEM C .   ? 0.36896 0.33002 0.19374 -0.09786 -0.07875 0.01939  1   BEM C C4  
3674 O O4  . BEM C .   ? 0.31193 0.32534 0.19781 -0.07954 -0.07148 0.01184  1   BEM C O4  
3675 C C5  . BEM C .   ? 0.45481 0.35336 0.25024 -0.10670 -0.05775 0.02397  1   BEM C C5  
3676 O O5  . BEM C .   ? 0.46749 0.35150 0.25896 -0.10676 -0.05415 0.04717  1   BEM C O5  
3677 C C6  . BEM C .   ? 0.52199 0.37723 0.32121 -0.11072 -0.01809 0.00754  1   BEM C C6  
3678 O O6B . BEM C .   ? 0.55523 0.38554 0.32020 -0.11029 -0.01910 0.00743  1   BEM C O6B 
3679 O O6A . BEM C .   ? 0.53956 0.38797 0.35396 -0.11294 0.00466  -0.00237 1   BEM C O6A 
3680 O O1  . BEM C .   ? 0.46810 0.34536 0.27170 -0.09613 -0.07839 0.03390  1   BEM C O1  
3689 C C1  . BEM C .   ? 0.27763 0.32996 0.18169 -0.05937 -0.04841 0.01623  2   BEM C C1  
3690 C C2  . BEM C .   ? 0.27143 0.32349 0.18705 -0.05149 -0.06511 0.01036  2   BEM C C2  
3691 O O2  . BEM C .   ? 0.26558 0.31356 0.22910 -0.05765 -0.07009 0.01941  2   BEM C O2  
3692 C C3  . BEM C .   ? 0.26592 0.32804 0.19102 -0.05293 -0.07290 -0.01199 2   BEM C C3  
3693 O O3  . BEM C .   ? 0.28469 0.33076 0.24124 -0.05330 -0.08524 -0.01777 2   BEM C O3  
3694 C C4  . BEM C .   ? 0.24078 0.33139 0.19704 -0.03850 -0.03637 -0.00696 2   BEM C C4  
3695 O O4  . BEM C .   ? 0.24753 0.32834 0.21869 -0.02009 -0.01912 -0.03423 2   BEM C O4  
3696 C C5  . BEM C .   ? 0.22923 0.33893 0.18264 -0.03766 -0.02938 0.00194  2   BEM C C5  
3697 O O5  . BEM C .   ? 0.25467 0.33870 0.17811 -0.04205 -0.04062 0.01426  2   BEM C O5  
3698 C C6  . BEM C .   ? 0.21869 0.35199 0.21500 -0.01591 -0.02551 0.01671  2   BEM C C6  
3699 O O6B . BEM C .   ? 0.23496 0.36661 0.26006 -0.01053 -0.01323 0.01821  2   BEM C O6B 
3700 O O6A . BEM C .   ? 0.21157 0.34549 0.21487 -0.01176 -0.02648 0.03290  2   BEM C O6A 
3708 C C1  . BEM C .   ? 0.26674 0.33391 0.24503 -0.00497 -0.00752 -0.04998 3   BEM C C1  
3709 C C2  . BEM C .   ? 0.29133 0.34252 0.27138 0.00202  -0.01273 -0.06410 3   BEM C C2  
3710 O O2  . BEM C .   ? 0.31388 0.35250 0.28894 0.00506  -0.01256 -0.06849 3   BEM C O2  
3711 C C3  . BEM C .   ? 0.29376 0.33855 0.27889 0.00434  -0.02191 -0.05443 3   BEM C C3  
3712 O O3  . BEM C .   ? 0.29689 0.34387 0.31647 0.00958  -0.02055 -0.03553 3   BEM C O3  
3713 C C4  . BEM C .   ? 0.29824 0.32975 0.24203 0.00319  -0.01671 -0.05725 3   BEM C C4  
3714 O O4  . BEM C .   ? 0.32538 0.32674 0.24764 -0.00102 -0.02465 -0.05549 3   BEM C O4  
3715 C C5  . BEM C .   ? 0.28697 0.33231 0.24114 0.00398  -0.01090 -0.04323 3   BEM C C5  
3716 O O5  . BEM C .   ? 0.27350 0.33258 0.21994 -0.01091 0.00022  -0.05047 3   BEM C O5  
3717 C C6  . BEM C .   ? 0.28950 0.34192 0.25079 0.01287  -0.02413 -0.04367 3   BEM C C6  
3718 O O6B . BEM C .   ? 0.28900 0.33594 0.22901 0.02661  -0.02934 -0.03695 3   BEM C O6B 
3719 O O6A . BEM C .   ? 0.30052 0.35557 0.25865 0.01270  -0.02697 -0.04742 3   BEM C O6A 
3727 C C1  . BEM C .   ? 0.38617 0.32775 0.29140 -0.00039 0.00496  -0.06933 4   BEM C C1  
3728 C C2  . BEM C .   ? 0.40004 0.32647 0.30192 -0.01147 -0.01563 -0.06641 4   BEM C C2  
3729 O O2  . BEM C .   ? 0.36757 0.32468 0.29405 -0.00474 -0.03665 -0.05143 4   BEM C O2  
3730 C C3  . BEM C .   ? 0.44672 0.32458 0.31964 -0.02604 0.01646  -0.09107 4   BEM C C3  
3731 O O3  . BEM C .   ? 0.45826 0.31929 0.31309 -0.03719 0.01280  -0.09167 4   BEM C O3  
3732 C C4  . BEM C .   ? 0.48587 0.33667 0.36588 -0.03317 0.05035  -0.10171 4   BEM C C4  
3733 O O4  . BEM C .   ? 0.50707 0.34517 0.39190 -0.05044 0.05421  -0.10368 4   BEM C O4  
3734 C C5  . BEM C .   ? 0.49911 0.34467 0.39035 -0.01916 0.07619  -0.10069 4   BEM C C5  
3735 O O5  . BEM C .   ? 0.43605 0.33685 0.33701 -0.00268 0.04192  -0.08482 4   BEM C O5  
3736 C C6  . BEM C .   ? 0.56793 0.36740 0.46914 -0.02139 0.12817  -0.10931 4   BEM C C6  
3737 O O6B . BEM C .   ? 0.60227 0.38215 0.50538 -0.02551 0.13193  -0.10549 4   BEM C O6B 
3738 O O6A . BEM C .   ? 0.58675 0.37566 0.50030 -0.01648 0.15606  -0.10928 4   BEM C O6A 
3747 O O   . HOH D .   ? 1.04623 0.47675 0.40259 -0.23294 -0.03277 -0.01268 301 HOH A O   
3748 O O   . HOH D .   ? 0.59709 1.07191 0.81785 -0.11969 0.28987  -0.15755 302 HOH A O   
3749 O O   . HOH D .   ? 0.57081 0.53596 0.86342 -0.00401 -0.37794 -0.04856 303 HOH A O   
3750 O O   . HOH D .   ? 1.41981 1.44465 1.25315 -0.18946 0.02204  -0.25085 304 HOH A O   
3751 O O   . HOH D .   ? 0.65789 0.59368 0.66190 0.21355  -0.20644 0.20870  305 HOH A O   
3752 O O   . HOH D .   ? 1.03782 0.47366 0.56132 0.10307  -0.32341 -0.17231 306 HOH A O   
3753 O O   . HOH D .   ? 0.32423 0.56909 0.52729 0.13984  -0.02259 -0.11160 307 HOH A O   
3754 O O   . HOH D .   ? 1.12237 0.40689 0.31579 0.01614  -0.15030 0.00824  308 HOH A O   
3755 O O   . HOH D .   ? 0.65811 0.84352 0.29767 -0.33147 0.08270  -0.03958 309 HOH A O   
3756 O O   . HOH D .   ? 1.38454 1.08037 0.98662 -0.29233 0.05022  0.17051  310 HOH A O   
3757 O O   . HOH D .   ? 0.54078 0.52438 0.51459 0.06499  -0.04034 -0.04282 311 HOH A O   
3758 O O   . HOH D .   ? 0.51645 0.63841 0.36977 0.10803  0.22594  0.11102  312 HOH A O   
3759 O O   . HOH D .   ? 0.27814 0.61780 0.71499 -0.02026 -0.15899 -0.15625 313 HOH A O   
3760 O O   . HOH D .   ? 0.28999 0.42864 0.96831 -0.03765 -0.09384 -0.05412 314 HOH A O   
3761 O O   . HOH D .   ? 0.78998 0.47947 0.50859 -0.27442 -0.32269 0.19468  315 HOH A O   
3762 O O   . HOH D .   ? 0.45650 0.65085 0.66423 -0.19302 -0.14010 0.23023  316 HOH A O   
3763 O O   . HOH D .   ? 0.36912 0.17842 0.59068 -0.00517 0.02208  0.01229  317 HOH A O   
3764 O O   . HOH D .   ? 0.59540 0.45257 0.28250 0.19434  -0.16030 -0.11028 318 HOH A O   
3765 O O   . HOH D .   ? 0.73154 0.88100 0.38964 -0.14022 0.12642  0.05156  319 HOH A O   
3766 O O   . HOH D .   ? 0.16577 0.22186 0.25248 0.05359  -0.02943 -0.03021 320 HOH A O   
3767 O O   . HOH D .   ? 0.52574 0.51589 0.91483 0.03526  -0.03128 -0.27625 321 HOH A O   
3768 O O   . HOH D .   ? 1.15532 0.45577 0.41449 0.30633  -0.23800 -0.08063 322 HOH A O   
3769 O O   . HOH D .   ? 0.35601 0.52245 0.66302 0.03418  -0.02159 0.03502  323 HOH A O   
3770 O O   . HOH D .   ? 0.38708 0.29709 0.38082 0.07372  -0.04771 0.01263  324 HOH A O   
3771 O O   . HOH D .   ? 0.10756 0.23332 0.23187 0.00357  -0.06013 0.04198  325 HOH A O   
3772 O O   . HOH D .   ? 0.36944 0.33109 0.52187 0.01937  -0.00805 -0.06437 326 HOH A O   
3773 O O   . HOH D .   ? 0.53408 0.93405 0.51759 0.32099  0.00374  -0.15085 327 HOH A O   
3774 O O   . HOH D .   ? 0.17306 0.32722 0.46730 0.02341  -0.10120 -0.07541 328 HOH A O   
3775 O O   . HOH D .   ? 0.16368 0.25780 0.27653 -0.01420 -0.01316 0.01650  329 HOH A O   
3776 O O   . HOH D .   ? 0.95852 0.53578 0.26456 -0.15583 -0.07962 0.00249  330 HOH A O   
3777 O O   . HOH D .   ? 0.40236 0.88846 0.70630 -0.02782 -0.29103 -0.02539 331 HOH A O   
3778 O O   . HOH D .   ? 0.40321 0.49475 0.50008 -0.07629 -0.16342 -0.04877 332 HOH A O   
3779 O O   . HOH D .   ? 0.52275 0.88568 0.37400 0.24732  -0.16012 -0.07077 333 HOH A O   
3780 O O   . HOH D .   ? 0.29720 0.42008 0.41129 0.16566  -0.13076 -0.03840 334 HOH A O   
3781 O O   . HOH D .   ? 0.31711 0.27008 0.37225 -0.04185 -0.16743 -0.03057 335 HOH A O   
3782 O O   . HOH D .   ? 0.95544 0.62475 0.44616 0.27506  0.16537  0.07550  336 HOH A O   
3783 O O   . HOH D .   ? 0.19293 0.35743 0.29824 -0.04662 -0.07519 0.05327  337 HOH A O   
3784 O O   . HOH D .   ? 0.18266 0.18165 0.20378 0.01838  -0.04307 0.01002  338 HOH A O   
3785 O O   . HOH D .   ? 0.16260 0.23085 0.20935 0.00628  -0.10874 0.00014  339 HOH A O   
3786 O O   . HOH D .   ? 0.15793 0.16675 0.24778 0.00792  -0.08005 -0.00705 340 HOH A O   
3787 O O   . HOH D .   ? 0.44935 0.67668 0.55077 -0.02919 0.03960  -0.18103 341 HOH A O   
3788 O O   . HOH D .   ? 0.71974 0.82624 0.70563 0.33480  -0.09018 0.23607  342 HOH A O   
3789 O O   . HOH D .   ? 0.62956 0.28987 0.50949 0.08167  0.28840  0.04982  343 HOH A O   
3790 O O   . HOH D .   ? 0.17425 0.23751 0.21454 0.00797  -0.08689 0.02220  344 HOH A O   
3791 O O   . HOH D .   ? 0.28466 0.25445 0.32762 -0.07998 -0.09048 0.07140  345 HOH A O   
3792 O O   . HOH D .   ? 0.37456 0.57193 0.37544 -0.25477 -0.02512 0.09857  346 HOH A O   
3793 O O   . HOH D .   ? 0.64967 0.51070 0.31942 0.26451  -0.10289 0.04102  347 HOH A O   
3794 O O   . HOH D .   ? 0.47806 0.68275 0.25602 -0.10644 -0.11329 0.12677  348 HOH A O   
3795 O O   . HOH D .   ? 0.27806 0.31759 0.36014 -0.07016 -0.08446 0.02038  349 HOH A O   
3796 O O   . HOH D .   ? 0.32954 0.81727 0.47738 0.17041  -0.12451 -0.27101 350 HOH A O   
3797 O O   . HOH D .   ? 0.22612 0.59656 0.61403 -0.09219 0.06272  -0.18679 351 HOH A O   
3798 O O   . HOH D .   ? 0.43271 0.50481 0.38243 -0.04070 -0.20959 -0.04224 352 HOH A O   
3799 O O   . HOH D .   ? 0.51757 0.71187 0.77729 0.12122  -0.14312 0.12490  353 HOH A O   
3800 O O   . HOH D .   ? 0.60867 0.31336 0.39155 0.07180  0.01504  0.12487  354 HOH A O   
3801 O O   . HOH D .   ? 0.57010 0.42665 0.70901 -0.24829 0.12898  -0.13404 355 HOH A O   
3802 O O   . HOH D .   ? 0.24943 0.32938 0.29529 -0.05675 -0.12112 -0.00351 356 HOH A O   
3803 O O   . HOH D .   ? 1.03093 0.32514 0.48915 -0.05118 0.13965  0.09473  357 HOH A O   
3804 O O   . HOH D .   ? 0.94553 0.46291 0.62657 -0.27143 0.07129  -0.12300 358 HOH A O   
3805 O O   . HOH D .   ? 0.37572 0.57632 0.84477 -0.07069 -0.23419 -0.12099 359 HOH A O   
3806 O O   . HOH D .   ? 0.58874 0.62960 0.47513 0.18542  -0.28292 -0.11852 360 HOH A O   
3807 O O   . HOH D .   ? 0.90270 0.51774 0.53820 0.32015  -0.01490 -0.10680 361 HOH A O   
3808 O O   . HOH D .   ? 0.86161 0.57902 0.54379 0.27413  -0.03554 -0.02379 362 HOH A O   
3809 O O   . HOH D .   ? 0.22422 0.20551 0.25888 0.02633  0.00397  0.00823  363 HOH A O   
3810 O O   . HOH D .   ? 0.27498 0.47914 0.86991 -0.00727 -0.00555 -0.20043 364 HOH A O   
3811 O O   . HOH D .   ? 0.21107 0.27594 0.22428 0.00400  -0.02787 0.02405  365 HOH A O   
3812 O O   . HOH D .   ? 0.37331 0.28105 0.37771 0.04029  -0.16764 0.00259  366 HOH A O   
3813 O O   . HOH D .   ? 0.18298 0.29210 0.34338 -0.01400 -0.09945 0.00013  367 HOH A O   
3814 O O   . HOH D .   ? 0.12756 0.14578 0.18481 -0.02006 -0.07681 0.01482  368 HOH A O   
3815 O O   . HOH D .   ? 0.14087 0.43231 0.49667 -0.00574 -0.06472 0.02668  369 HOH A O   
3816 O O   . HOH D .   ? 0.14930 0.18316 0.21466 -0.00656 -0.08743 0.00372  370 HOH A O   
3817 O O   . HOH D .   ? 0.51323 0.39508 0.54674 0.10037  -0.24155 -0.10755 371 HOH A O   
3818 O O   . HOH D .   ? 0.11220 0.22929 0.16544 0.00802  -0.05539 -0.01737 372 HOH A O   
3819 O O   . HOH D .   ? 0.47071 0.61544 0.47779 0.30001  -0.07022 0.03127  373 HOH A O   
3820 O O   . HOH D .   ? 0.09881 0.23653 0.24189 -0.00533 -0.05588 -0.00293 374 HOH A O   
3821 O O   . HOH D .   ? 0.58174 0.38334 0.83707 -0.14044 0.18476  -0.24565 375 HOH A O   
3822 O O   . HOH D .   ? 0.24845 0.36542 0.42659 0.09799  -0.04670 0.05539  376 HOH A O   
3823 O O   . HOH D .   ? 0.19899 0.69591 0.26908 0.03038  -0.02739 -0.02364 377 HOH A O   
3824 O O   . HOH D .   ? 0.24141 0.34099 0.46123 0.06051  -0.16695 -0.10138 378 HOH A O   
3825 O O   . HOH D .   ? 0.28759 0.27599 0.49083 0.02869  -0.08032 -0.02934 379 HOH A O   
3826 O O   . HOH D .   ? 0.18154 0.44450 0.41937 0.03311  -0.13045 -0.00389 380 HOH A O   
3827 O O   . HOH D .   ? 0.22885 0.28095 0.34655 0.02500  -0.12400 0.01370  381 HOH A O   
3828 O O   . HOH D .   ? 0.41924 0.42770 0.47127 -0.18113 -0.23116 0.19822  382 HOH A O   
3829 O O   . HOH D .   ? 0.19526 0.30340 0.22049 0.00975  -0.03507 0.04439  383 HOH A O   
3830 O O   . HOH D .   ? 0.40332 0.79576 0.38780 -0.02265 -0.16039 0.15975  384 HOH A O   
3831 O O   . HOH D .   ? 0.31150 0.25663 0.24534 -0.07361 -0.14879 0.06523  385 HOH A O   
3832 O O   . HOH D .   ? 0.17754 0.17658 0.27514 -0.02140 -0.07800 0.00330  386 HOH A O   
3833 O O   . HOH D .   ? 0.71864 0.47895 0.75754 0.15950  0.23326  -0.06714 387 HOH A O   
3834 O O   . HOH D .   ? 0.48494 0.43349 0.74800 0.01919  0.23979  0.10207  388 HOH A O   
3835 O O   . HOH D .   ? 0.79574 0.38757 0.35011 -0.08918 -0.20383 0.11793  389 HOH A O   
3836 O O   . HOH D .   ? 0.12383 0.20144 0.17271 -0.00314 -0.08116 0.01008  390 HOH A O   
3837 O O   . HOH D .   ? 0.18470 0.40865 0.30098 0.02009  -0.10844 -0.07967 391 HOH A O   
3838 O O   . HOH D .   ? 0.18282 0.25265 0.23464 0.00791  -0.05621 0.00230  392 HOH A O   
3839 O O   . HOH D .   ? 0.42011 0.49893 0.34476 -0.19415 -0.17614 0.07832  393 HOH A O   
3840 O O   . HOH D .   ? 0.12718 0.17982 0.27547 0.04550  -0.01915 0.02602  394 HOH A O   
3841 O O   . HOH D .   ? 0.42011 0.74306 0.64573 0.16212  -0.16899 -0.14380 395 HOH A O   
3842 O O   . HOH D .   ? 0.17337 0.37958 0.36468 -0.06456 0.00315  -0.08393 396 HOH A O   
3843 O O   . HOH D .   ? 0.27308 0.35533 0.35343 0.02326  -0.03076 0.00567  397 HOH A O   
3844 O O   . HOH D .   ? 0.32415 0.27619 0.35153 -0.04800 -0.19578 0.07091  398 HOH A O   
3845 O O   . HOH D .   ? 0.29630 0.34749 0.32379 0.02566  -0.06208 -0.02891 399 HOH A O   
3846 O O   . HOH D .   ? 0.17413 0.20858 0.27327 0.00425  -0.09199 0.01390  400 HOH A O   
3847 O O   . HOH D .   ? 0.57711 0.30603 0.81814 -0.07982 -0.31867 0.14340  401 HOH A O   
3848 O O   . HOH D .   ? 0.17314 0.31033 0.39097 0.02493  0.03570  -0.02652 402 HOH A O   
3849 O O   . HOH D .   ? 0.36662 0.50564 0.89459 0.15186  -0.18689 -0.09190 403 HOH A O   
3850 O O   . HOH D .   ? 0.34767 0.24604 0.69957 0.05022  0.05025  -0.11402 404 HOH A O   
3851 O O   . HOH D .   ? 0.22345 0.24771 0.25072 -0.00100 -0.10898 -0.03433 405 HOH A O   
3852 O O   . HOH D .   ? 0.15423 0.22885 0.31183 0.01137  -0.06379 0.02664  406 HOH A O   
3853 O O   . HOH D .   ? 0.14993 0.17765 0.24811 -0.02854 -0.08598 0.01298  407 HOH A O   
3854 O O   . HOH D .   ? 0.24341 0.31340 0.40004 -0.05209 -0.16962 0.04571  408 HOH A O   
3855 O O   . HOH D .   ? 0.48371 0.43385 0.33720 0.02173  0.10057  -0.05451 409 HOH A O   
3856 O O   . HOH D .   ? 0.29225 0.49193 0.48049 0.11920  0.03334  0.03535  410 HOH A O   
3857 O O   . HOH D .   ? 0.22675 0.26512 0.42660 0.00022  -0.16782 0.01533  411 HOH A O   
3858 O O   . HOH D .   ? 0.18281 0.21161 0.20094 -0.03113 -0.03810 -0.00089 412 HOH A O   
3859 O O   . HOH D .   ? 0.14035 0.18487 0.18867 -0.01671 -0.06454 -0.01204 413 HOH A O   
3860 O O   . HOH D .   ? 0.14797 0.17163 0.21821 0.01088  -0.05600 0.00107  414 HOH A O   
3861 O O   . HOH D .   ? 0.36033 0.28442 0.56885 -0.01668 -0.15521 0.03250  415 HOH A O   
3862 O O   . HOH D .   ? 0.54349 0.54870 0.72090 0.03954  0.22746  -0.19566 416 HOH A O   
3863 O O   . HOH D .   ? 0.47124 0.40614 0.38982 -0.12475 0.02166  -0.20532 417 HOH A O   
3864 O O   . HOH D .   ? 0.33308 0.34682 0.95120 -0.06209 -0.08618 0.21725  418 HOH A O   
3865 O O   . HOH D .   ? 0.19207 0.60384 0.35793 0.04133  -0.02784 0.03484  419 HOH A O   
3866 O O   . HOH D .   ? 0.22321 0.22049 0.32678 -0.05896 -0.05852 -0.04355 420 HOH A O   
3867 O O   . HOH D .   ? 0.40975 0.37758 0.25043 0.04577  -0.15241 0.01405  421 HOH A O   
3868 O O   . HOH D .   ? 0.10756 0.25752 0.27054 0.02087  -0.04079 -0.02115 422 HOH A O   
3869 O O   . HOH D .   ? 0.37599 0.51642 0.68440 -0.00043 0.16254  0.26909  423 HOH A O   
3870 O O   . HOH D .   ? 0.17669 0.21016 0.19630 0.01208  -0.03724 0.02687  424 HOH A O   
3871 O O   . HOH D .   ? 0.31918 0.32408 0.32530 0.09994  -0.11101 -0.01929 425 HOH A O   
3872 O O   . HOH D .   ? 0.14189 0.23369 0.20501 0.02564  -0.07838 0.00144  426 HOH A O   
3873 O O   . HOH D .   ? 0.58061 0.37352 0.48348 0.13614  -0.24993 0.03056  427 HOH A O   
3874 O O   . HOH D .   ? 0.20728 0.23190 0.23896 0.00990  -0.12097 -0.01944 428 HOH A O   
3875 O O   . HOH D .   ? 0.62935 0.34256 0.29816 -0.06591 0.05991  0.00078  429 HOH A O   
3876 O O   . HOH D .   ? 0.35152 0.38139 0.40042 0.03482  0.01599  0.00153  430 HOH A O   
3877 O O   . HOH D .   ? 0.30795 0.41384 0.33756 -0.06923 -0.11632 0.10624  431 HOH A O   
3878 O O   . HOH D .   ? 0.50831 1.06584 0.69494 -0.20939 -0.10363 0.34629  432 HOH A O   
3879 O O   . HOH D .   ? 0.42185 0.64839 0.35609 -0.01707 -0.18231 0.09534  433 HOH A O   
3880 O O   . HOH D .   ? 0.46990 0.43945 0.69560 0.24441  0.11649  0.00781  434 HOH A O   
3881 O O   . HOH D .   ? 0.19340 0.27745 0.32827 0.03935  -0.08273 0.04474  435 HOH A O   
3882 O O   . HOH D .   ? 0.21738 0.27450 0.22639 0.01063  -0.05388 0.02127  436 HOH A O   
3883 O O   . HOH D .   ? 0.95177 0.51262 0.37440 -0.01878 -0.04804 0.13701  437 HOH A O   
3884 O O   . HOH D .   ? 0.23255 0.28614 0.29045 0.01819  -0.08168 -0.03023 438 HOH A O   
3885 O O   . HOH D .   ? 0.65628 0.27101 0.42822 -0.04125 -0.28319 0.06779  439 HOH A O   
3886 O O   . HOH D .   ? 0.68801 0.50306 0.45483 0.09815  0.16968  0.02405  440 HOH A O   
3887 O O   . HOH D .   ? 0.18445 0.15405 0.25792 0.01857  -0.05317 0.00105  441 HOH A O   
3888 O O   . HOH D .   ? 0.17241 0.16467 0.21451 -0.00609 -0.03967 -0.01312 442 HOH A O   
3889 O O   . HOH D .   ? 0.24778 0.29522 0.30615 0.01782  -0.08094 -0.02148 443 HOH A O   
3890 O O   . HOH D .   ? 0.30066 0.34825 0.37543 -0.07870 -0.16163 0.12858  444 HOH A O   
3891 O O   . HOH D .   ? 0.41905 0.26164 0.37344 -0.11005 -0.17634 0.06522  445 HOH A O   
3892 O O   . HOH D .   ? 0.30452 0.34762 0.31987 -0.04943 -0.07855 0.02690  446 HOH A O   
3893 O O   . HOH D .   ? 0.95735 0.52027 0.54577 0.30753  -0.07152 0.04052  447 HOH A O   
3894 O O   . HOH D .   ? 0.19994 0.32729 0.26991 -0.12412 -0.06012 0.01974  448 HOH A O   
3895 O O   . HOH D .   ? 0.37476 0.62745 0.82843 -0.05529 0.12132  -0.40762 449 HOH A O   
3896 O O   . HOH D .   ? 0.27001 0.38552 0.18708 -0.10371 -0.00887 -0.01416 450 HOH A O   
3897 O O   . HOH D .   ? 0.81161 0.48917 0.37461 -0.20040 -0.11194 -0.06452 451 HOH A O   
3898 O O   . HOH D .   ? 0.22241 0.50083 0.31591 -0.12005 -0.08976 0.00103  452 HOH A O   
3899 O O   . HOH D .   ? 0.28521 0.69270 0.59442 0.08050  0.14924  0.01130  453 HOH A O   
3900 O O   . HOH D .   ? 0.74702 0.72606 0.76363 0.36458  -0.32104 -0.15906 454 HOH A O   
3901 O O   . HOH D .   ? 0.16789 0.37887 0.45997 -0.02023 -0.09380 -0.08525 455 HOH A O   
3902 O O   . HOH D .   ? 0.30110 0.77518 0.72486 0.14394  0.16323  -0.05258 456 HOH A O   
3903 O O   . HOH D .   ? 0.43973 0.65486 0.40331 -0.02089 0.06363  0.07047  457 HOH A O   
3904 O O   . HOH D .   ? 0.39321 1.08446 0.55796 -0.19216 0.07655  0.15627  458 HOH A O   
3905 O O   . HOH D .   ? 0.15690 0.22557 0.43117 0.01820  -0.10495 0.01414  459 HOH A O   
3906 O O   . HOH D .   ? 0.27580 0.33904 0.53560 0.06127  0.12627  0.06874  460 HOH A O   
3907 O O   . HOH D .   ? 0.88677 0.54990 0.78627 0.27022  0.36399  0.27466  461 HOH A O   
3908 O O   . HOH D .   ? 0.66839 0.39129 0.60430 -0.06701 -0.24512 -0.12315 462 HOH A O   
3909 O O   . HOH D .   ? 0.12835 0.17660 0.20648 0.00629  -0.06495 0.02328  463 HOH A O   
3910 O O   . HOH D .   ? 0.64460 1.07154 0.32343 0.30662  -0.06710 -0.05378 464 HOH A O   
3911 O O   . HOH D .   ? 0.22896 0.69255 0.46096 0.11218  0.01997  0.17226  465 HOH A O   
3912 O O   . HOH D .   ? 0.35454 0.29670 0.38853 -0.07023 -0.15138 0.12285  466 HOH A O   
3913 O O   . HOH D .   ? 0.66830 0.38405 0.77957 0.14289  0.10208  0.24961  467 HOH A O   
3914 O O   . HOH D .   ? 0.58253 1.14420 0.30022 -0.12201 -0.04494 0.03057  468 HOH A O   
3915 O O   . HOH D .   ? 0.27269 0.46774 0.34258 0.06711  -0.01269 0.03418  469 HOH A O   
3916 O O   . HOH D .   ? 0.14942 0.30729 0.31506 0.00846  -0.00709 0.05172  470 HOH A O   
3917 O O   . HOH D .   ? 0.26495 0.37768 0.25450 -0.03668 -0.11704 0.07038  471 HOH A O   
3918 O O   . HOH D .   ? 0.36409 0.71872 0.26935 -0.04751 -0.12210 0.06001  472 HOH A O   
3919 O O   . HOH D .   ? 0.42429 0.69991 0.48021 -0.05414 -0.26152 -0.04870 473 HOH A O   
3920 O O   . HOH D .   ? 0.30198 0.37480 0.48078 0.11877  -0.18727 -0.08985 474 HOH A O   
3921 O O   . HOH D .   ? 1.03221 0.33075 0.63293 -0.13216 -0.08140 0.12905  475 HOH A O   
3922 O O   . HOH D .   ? 0.35383 0.82093 0.43917 0.06360  0.02626  0.32368  476 HOH A O   
3923 O O   . HOH D .   ? 0.89852 0.39158 0.59101 0.14257  0.12865  0.08026  477 HOH A O   
3924 O O   . HOH D .   ? 0.41628 0.92601 0.38258 0.13890  0.04478  -0.21211 478 HOH A O   
3925 O O   . HOH D .   ? 0.31933 0.48727 0.26039 0.08335  -0.02914 0.01930  479 HOH A O   
3926 O O   . HOH D .   ? 0.50681 0.24450 0.45232 -0.05064 0.12108  0.06235  480 HOH A O   
3927 O O   . HOH D .   ? 0.37355 0.34827 0.24211 -0.10185 -0.15582 0.07298  481 HOH A O   
3928 O O   . HOH D .   ? 0.92083 0.53852 0.48610 -0.15061 0.00083  -0.06727 482 HOH A O   
3929 O O   . HOH D .   ? 0.37228 0.76569 0.65028 0.16648  0.02508  0.33283  483 HOH A O   
3930 O O   . HOH D .   ? 0.16089 0.28644 0.33807 0.00744  -0.04436 0.05026  484 HOH A O   
3931 O O   . HOH D .   ? 0.36862 0.65154 0.56577 -0.24048 0.09393  -0.19406 485 HOH A O   
3932 O O   . HOH D .   ? 0.63644 0.55276 0.42329 -0.31813 0.05053  -0.14504 486 HOH A O   
3933 O O   . HOH D .   ? 0.52720 0.56203 0.53453 0.06292  0.15545  0.27884  487 HOH A O   
3934 O O   . HOH D .   ? 0.21047 0.35580 0.20744 -0.03711 -0.06015 0.03718  488 HOH A O   
3935 O O   . HOH D .   ? 0.24671 0.87007 0.50227 -0.07298 -0.02775 -0.13764 489 HOH A O   
3936 O O   . HOH D .   ? 0.12620 0.28427 0.22444 0.02753  -0.08002 -0.03808 490 HOH A O   
3937 O O   . HOH D .   ? 0.22653 0.61340 0.31492 -0.04933 0.04139  -0.12849 491 HOH A O   
3938 O O   . HOH D .   ? 0.70965 0.69375 0.31147 -0.21349 0.15178  -0.07569 492 HOH A O   
3939 O O   . HOH D .   ? 0.26303 0.35782 0.24776 -0.06368 -0.12133 0.04099  493 HOH A O   
3940 O O   . HOH D .   ? 0.18267 0.24146 0.33918 0.03349  -0.08185 0.02745  494 HOH A O   
3941 O O   . HOH D .   ? 0.39304 0.51288 0.32653 -0.16186 0.02318  0.03642  495 HOH A O   
3942 O O   . HOH D .   ? 0.42662 0.32327 0.37749 0.09769  -0.13625 0.07536  496 HOH A O   
3943 O O   . HOH D .   ? 0.38805 0.37456 0.48708 0.09878  -0.17030 -0.12035 497 HOH A O   
3944 O O   . HOH D .   ? 0.50849 0.66879 0.47838 0.07392  0.00801  0.08417  498 HOH A O   
3945 O O   . HOH D .   ? 0.26361 0.70115 0.30548 0.00807  0.05806  0.02315  499 HOH A O   
3946 O O   . HOH D .   ? 0.16555 0.20347 0.30766 0.00834  -0.05285 -0.02458 500 HOH A O   
3947 O O   . HOH D .   ? 0.37975 0.58265 0.70928 -0.13699 0.03923  -0.18270 501 HOH A O   
3948 O O   . HOH D .   ? 0.26746 0.36763 0.35703 -0.08329 -0.09826 -0.04238 502 HOH A O   
3949 O O   . HOH D .   ? 0.16810 0.22800 0.32266 -0.03081 -0.11908 0.00224  503 HOH A O   
3950 O O   . HOH D .   ? 0.42363 0.43386 0.44966 0.02787  -0.00923 0.04264  504 HOH A O   
3951 O O   . HOH D .   ? 0.67454 0.73492 0.26644 0.13974  0.13050  -0.04935 505 HOH A O   
3952 O O   . HOH D .   ? 0.28756 0.40791 0.61058 0.04526  -0.20979 -0.02062 506 HOH A O   
3953 O O   . HOH D .   ? 0.66733 1.00581 0.90073 -0.19167 -0.05936 0.43073  507 HOH A O   
3954 O O   . HOH D .   ? 0.38646 0.39249 0.30443 0.05043  -0.02644 -0.13363 508 HOH A O   
3955 O O   . HOH D .   ? 0.49703 0.81074 0.53286 -0.15496 0.11625  0.21680  509 HOH A O   
3956 O O   . HOH D .   ? 0.40601 0.46112 0.85168 0.11178  -0.16561 -0.28537 510 HOH A O   
3957 O O   . HOH D .   ? 0.47378 0.52161 0.36744 0.23561  -0.04714 0.05808  511 HOH A O   
3958 O O   . HOH D .   ? 0.32498 0.52841 0.36132 0.11906  -0.16833 -0.00657 512 HOH A O   
3959 O O   . HOH D .   ? 0.38541 0.73110 0.77319 0.13565  -0.21031 0.14003  513 HOH A O   
3960 O O   . HOH D .   ? 0.41811 0.77981 0.87431 -0.05238 0.14697  -0.26165 514 HOH A O   
3961 O O   . HOH D .   ? 0.13574 0.20683 0.19331 -0.01079 -0.04947 0.01796  515 HOH A O   
3962 O O   . HOH D .   ? 0.54131 0.60905 0.43023 0.02101  -0.04232 0.19097  516 HOH A O   
3963 O O   . HOH D .   ? 0.58402 0.42951 0.74821 0.01665  0.04661  0.20057  517 HOH A O   
3964 O O   . HOH D .   ? 0.27543 0.54064 0.45976 -0.07280 -0.05338 0.11925  518 HOH A O   
3965 O O   . HOH D .   ? 0.17865 0.44232 0.41582 -0.05900 -0.01460 -0.17265 519 HOH A O   
3966 O O   . HOH D .   ? 0.29795 0.36869 0.25199 -0.02216 -0.05464 -0.01311 520 HOH A O   
3967 O O   . HOH D .   ? 0.41421 0.90362 0.57319 0.22438  -0.00341 -0.16671 521 HOH A O   
3968 O O   . HOH D .   ? 0.65968 0.72975 0.87953 0.13535  -0.10818 -0.45246 522 HOH A O   
3969 O O   . HOH D .   ? 0.21147 0.36916 0.24242 0.00511  -0.01503 0.03706  523 HOH A O   
3970 O O   . HOH D .   ? 0.32693 0.68257 0.57050 -0.22622 0.07690  -0.12393 524 HOH A O   
3971 O O   . HOH D .   ? 0.39838 0.94633 0.71016 0.21643  -0.10819 -0.26059 525 HOH A O   
3972 O O   . HOH D .   ? 0.44177 0.48238 0.71020 -0.12642 0.17987  -0.14362 526 HOH A O   
3973 O O   . HOH D .   ? 0.42646 1.04070 0.67763 -0.12142 0.06113  -0.12820 527 HOH A O   
3974 O O   . HOH D .   ? 0.26440 0.43551 0.23608 -0.09205 -0.11804 0.02108  528 HOH A O   
3975 O O   . HOH D .   ? 0.43919 0.40378 0.39197 -0.01327 0.01896  -0.15296 529 HOH A O   
3976 O O   . HOH D .   ? 0.91279 0.44556 0.40122 -0.05250 -0.23374 0.10636  530 HOH A O   
3977 O O   . HOH D .   ? 0.71424 0.41392 0.64855 -0.08216 0.07897  -0.09375 531 HOH A O   
3978 O O   . HOH D .   ? 0.17995 0.46053 0.62839 -0.03258 -0.02877 -0.11508 532 HOH A O   
3979 O O   . HOH D .   ? 0.77448 0.59869 0.85723 0.30649  0.18394  0.19794  533 HOH A O   
3980 O O   . HOH D .   ? 0.50168 0.78395 0.52115 0.12909  -0.26407 0.07620  534 HOH A O   
3981 O O   . HOH D .   ? 0.43156 1.20860 0.64415 -0.22380 -0.15141 0.15054  535 HOH A O   
3982 O O   . HOH D .   ? 0.49223 0.66326 0.68376 -0.23019 -0.08797 0.26702  536 HOH A O   
3983 O O   . HOH D .   ? 0.51337 0.40682 1.15090 0.05438  0.05437  0.20734  537 HOH A O   
3984 O O   . HOH D .   ? 0.43948 1.02834 0.59680 -0.22910 0.09847  -0.38591 538 HOH A O   
3985 O O   . HOH D .   ? 0.63013 0.62351 0.71417 -0.02623 -0.10946 -0.37748 539 HOH A O   
3986 O O   . HOH D .   ? 0.36998 0.94945 0.41787 -0.11295 -0.07720 -0.00075 540 HOH A O   
3987 O O   . HOH D .   ? 0.40968 0.45324 0.40121 0.10835  -0.22616 -0.10186 541 HOH A O   
3988 O O   . HOH D .   ? 0.28771 0.81279 0.56039 0.03832  0.01465  -0.23234 542 HOH A O   
3989 O O   . HOH D .   ? 0.91534 0.81668 1.15519 0.07273  0.41861  0.29000  543 HOH A O   
3990 O O   . HOH D .   ? 0.39997 0.47260 0.30182 0.02828  0.05444  0.04932  544 HOH A O   
3991 O O   . HOH D .   ? 0.37394 0.54763 0.44758 -0.07776 -0.16449 0.01479  545 HOH A O   
3992 O O   . HOH D .   ? 0.42150 0.94621 0.70479 -0.00625 0.27152  -0.10656 546 HOH A O   
3993 O O   . HOH D .   ? 0.59055 0.59890 0.34340 -0.14024 -0.15801 -0.09217 547 HOH A O   
3994 O O   . HOH D .   ? 0.25477 0.30563 0.78776 0.03533  -0.06338 0.07285  548 HOH A O   
3995 O O   . HOH D .   ? 0.49848 0.51609 0.68487 0.07861  -0.25757 -0.15837 549 HOH A O   
3996 O O   . HOH D .   ? 0.36308 0.32037 0.34062 -0.03750 -0.17957 0.03088  550 HOH A O   
3997 O O   . HOH D .   ? 0.30462 0.82699 0.48690 0.09749  -0.13097 0.07079  551 HOH A O   
3998 O O   . HOH D .   ? 0.38198 0.80293 0.59378 -0.05790 -0.04943 -0.03320 552 HOH A O   
3999 O O   . HOH D .   ? 0.50972 0.70955 0.51237 0.14001  -0.08583 -0.08467 553 HOH A O   
4000 O O   . HOH D .   ? 0.34402 0.50792 0.37054 0.02307  -0.06403 -0.06096 554 HOH A O   
4001 O O   . HOH D .   ? 0.39806 0.95703 0.59396 -0.16721 -0.07218 0.15604  555 HOH A O   
4002 O O   . HOH D .   ? 0.38977 0.54761 0.48095 0.09119  -0.22623 -0.16378 556 HOH A O   
4003 O O   . HOH D .   ? 0.73968 0.89783 0.36497 -0.35969 0.15581  -0.09960 557 HOH A O   
4004 O O   . HOH D .   ? 0.43723 0.71814 0.43058 0.02486  0.04022  0.04819  558 HOH A O   
4005 O O   . HOH D .   ? 0.28078 0.43342 0.32763 -0.04072 -0.14423 0.00229  559 HOH A O   
4006 O O   . HOH D .   ? 0.67335 0.96786 0.54041 0.16202  -0.16194 0.04401  560 HOH A O   
4007 O O   . HOH D .   ? 0.62585 1.20751 0.78803 0.35515  -0.13434 0.17853  561 HOH A O   
4008 O O   . HOH D .   ? 0.99367 0.41592 0.59161 -0.00904 0.34849  0.06317  562 HOH A O   
4009 O O   . HOH D .   ? 0.74950 0.55801 0.62701 0.03887  -0.09167 -0.23434 563 HOH A O   
4010 O O   . HOH D .   ? 0.61525 0.77437 0.77720 -0.03431 0.05819  0.44340  564 HOH A O   
4011 O O   . HOH D .   ? 0.44274 0.89864 0.57801 -0.02533 -0.18565 -0.25510 565 HOH A O   
4012 O O   . HOH D .   ? 0.67683 1.02092 0.43275 -0.41135 0.03007  -0.05466 566 HOH A O   
4013 O O   . HOH D .   ? 0.18851 0.18184 0.30688 0.02079  -0.03733 -0.02324 567 HOH A O   
4014 O O   . HOH D .   ? 0.84322 0.61125 0.47365 0.34957  -0.16663 -0.00221 568 HOH A O   
4015 O O   . HOH D .   ? 0.97792 1.22924 0.32761 -0.05333 0.09911  -0.04461 569 HOH A O   
4016 O O   . HOH D .   ? 0.61728 0.61946 0.49063 0.07982  0.08158  0.30913  570 HOH A O   
4017 O O   . HOH D .   ? 0.37293 0.57175 0.67396 -0.25531 -0.03094 -0.06325 571 HOH A O   
4018 O O   . HOH D .   ? 0.12490 0.27181 0.26610 0.01610  -0.06173 -0.00868 572 HOH A O   
4019 O O   . HOH D .   ? 1.07159 0.56381 0.33681 -0.09148 -0.00387 -0.04551 573 HOH A O   
4020 O O   . HOH D .   ? 0.55967 0.95035 0.55906 0.29837  -0.23025 -0.31654 574 HOH A O   
4021 O O   . HOH D .   ? 0.31631 0.57167 0.37502 -0.01452 0.03649  0.02898  575 HOH A O   
4022 O O   . HOH D .   ? 0.48369 0.66884 0.83251 -0.20079 -0.14119 -0.02046 576 HOH A O   
4023 O O   . HOH D .   ? 0.25716 0.35288 0.34952 0.06269  -0.05843 -0.09483 577 HOH A O   
4024 O O   . HOH D .   ? 0.53690 0.43940 0.86842 0.04728  0.19867  0.25215  578 HOH A O   
4025 O O   . HOH D .   ? 0.84994 0.79800 0.30875 -0.25181 0.13570  -0.06990 579 HOH A O   
4026 O O   . HOH D .   ? 0.60402 0.58930 0.41959 0.07629  -0.00825 -0.00863 580 HOH A O   
4027 O O   . HOH D .   ? 0.24252 0.30395 0.27946 -0.00782 -0.03310 -0.05054 581 HOH A O   
4028 O O   . HOH D .   ? 0.34315 0.48767 0.35130 -0.11391 -0.13172 0.00945  582 HOH A O   
4029 O O   . HOH D .   ? 0.58694 0.96507 0.51826 -0.19754 -0.08893 -0.18821 583 HOH A O   
4030 O O   . HOH D .   ? 0.15154 0.36316 0.33692 -0.02143 -0.10946 -0.01574 584 HOH A O   
4031 O O   . HOH D .   ? 0.42241 0.70534 0.50092 -0.07695 0.05413  0.00654  585 HOH A O   
4032 O O   . HOH D .   ? 0.69299 0.75146 0.45409 0.37178  -0.11425 0.04551  586 HOH A O   
4033 O O   . HOH D .   ? 0.30561 0.60409 0.86853 -0.11137 -0.16716 0.10327  587 HOH A O   
4034 O O   . HOH D .   ? 0.65698 0.69102 0.41024 0.02331  -0.05468 0.08819  588 HOH A O   
4035 O O   . HOH D .   ? 0.50614 0.63367 0.47699 -0.01736 -0.12574 0.00235  589 HOH A O   
4036 O O   . HOH D .   ? 0.39257 1.11676 0.43675 0.15243  -0.04291 0.19234  590 HOH A O   
4037 O O   . HOH D .   ? 0.54384 0.61199 0.62376 0.17766  -0.29323 0.01769  591 HOH A O   
4038 O O   . HOH D .   ? 0.40987 0.87909 0.56963 -0.26744 -0.01738 -0.17039 592 HOH A O   
4039 O O   . HOH D .   ? 0.22399 0.41626 0.40280 0.05102  -0.00291 0.15460  593 HOH A O   
4040 O O   . HOH D .   ? 0.69692 0.53479 0.59702 0.23824  -0.35338 -0.18967 594 HOH A O   
4041 O O   . HOH D .   ? 0.38378 0.38813 0.39316 -0.09394 -0.22155 0.06600  595 HOH A O   
4042 O O   . HOH D .   ? 0.72068 0.67260 0.79148 0.09328  -0.29494 0.28059  596 HOH A O   
4043 O O   . HOH D .   ? 0.23822 0.67012 0.53577 0.06224  -0.07865 -0.15170 597 HOH A O   
4044 O O   . HOH D .   ? 1.04333 0.43307 0.63098 -0.26418 -0.34838 0.11959  598 HOH A O   
4045 O O   . HOH D .   ? 0.55535 0.74940 0.56413 0.12119  -0.23874 -0.30036 599 HOH A O   
4046 O O   . HOH D .   ? 0.45098 1.19941 0.56625 -0.31606 -0.05947 0.09644  600 HOH A O   
4047 O O   . HOH D .   ? 0.33603 0.66370 0.40911 0.20834  0.00634  0.10532  601 HOH A O   
4048 O O   . HOH D .   ? 0.70203 0.54257 0.63289 -0.16109 -0.21483 -0.00041 602 HOH A O   
4049 O O   . HOH D .   ? 0.30267 0.38949 0.32538 -0.12217 -0.16161 0.08700  603 HOH A O   
4050 O O   . HOH D .   ? 0.75234 0.63894 0.45421 -0.16746 0.04270  -0.07376 604 HOH A O   
4051 O O   . HOH D .   ? 0.56086 0.60042 0.95059 0.08896  -0.04749 0.10330  605 HOH A O   
4052 O O   . HOH D .   ? 0.21692 0.41851 0.74268 -0.01844 0.00112  -0.07117 606 HOH A O   
4053 O O   . HOH D .   ? 0.84128 0.38818 0.39832 -0.11349 -0.01183 0.10954  607 HOH A O   
4054 O O   . HOH D .   ? 0.90561 0.53109 0.70515 -0.25020 -0.01228 0.10739  608 HOH A O   
4055 O O   . HOH D .   ? 0.50262 0.66813 0.39890 -0.14682 -0.23097 0.04035  609 HOH A O   
4056 O O   . HOH D .   ? 0.49493 0.38686 1.14541 0.07660  -0.25848 0.04154  610 HOH A O   
4057 O O   . HOH D .   ? 0.31889 0.34338 0.29385 -0.05954 -0.12975 0.06232  611 HOH A O   
4058 O O   . HOH D .   ? 0.45777 0.31636 1.01188 0.05320  -0.07445 -0.11925 612 HOH A O   
4059 O O   . HOH D .   ? 0.27609 0.50857 0.69044 -0.07830 0.06386  0.06672  613 HOH A O   
4060 O O   . HOH D .   ? 0.34494 0.42785 0.40439 -0.09149 -0.04194 0.09913  614 HOH A O   
4061 O O   . HOH D .   ? 0.66639 0.53364 0.63637 0.14250  -0.35206 -0.21672 615 HOH A O   
4062 O O   . HOH D .   ? 0.59936 0.53964 0.53073 -0.24641 0.08315  -0.18354 616 HOH A O   
4063 O O   . HOH D .   ? 0.23774 0.65480 0.44129 -0.02085 -0.09640 -0.15551 617 HOH A O   
4064 O O   . HOH D .   ? 0.33316 0.81427 0.65599 0.12496  -0.19065 -0.12018 618 HOH A O   
4065 O O   . HOH D .   ? 0.61726 0.53088 0.62560 0.02113  -0.23190 0.19163  619 HOH A O   
4066 O O   . HOH D .   ? 0.43350 0.50033 1.09354 0.10488  -0.25881 -0.13086 620 HOH A O   
4067 O O   . HOH D .   ? 0.68925 0.45935 0.55562 0.00075  -0.15824 0.03913  621 HOH A O   
4068 O O   . HOH D .   ? 0.28985 0.25720 0.42848 -0.01318 -0.08841 0.06759  622 HOH A O   
4069 O O   . HOH D .   ? 0.29089 0.57068 0.94386 -0.11319 0.04738  -0.14365 623 HOH A O   
4070 O O   . HOH D .   ? 0.72254 0.95299 0.58557 -0.13235 -0.23967 0.02915  624 HOH A O   
4071 O O   . HOH D .   ? 0.29456 0.46241 0.21722 -0.04964 -0.11762 0.00101  625 HOH A O   
4072 O O   . HOH D .   ? 0.76227 0.59697 0.46094 0.20755  0.11000  0.26253  626 HOH A O   
4073 O O   . HOH D .   ? 0.32709 0.50764 0.90712 0.01150  0.00080  -0.23174 627 HOH A O   
4074 O O   . HOH D .   ? 0.57272 0.91278 0.74573 -0.16838 0.03635  0.18259  628 HOH A O   
4075 O O   . HOH D .   ? 0.57750 0.66680 0.86553 -0.28517 0.24052  -0.30755 629 HOH A O   
4076 O O   . HOH D .   ? 0.47327 0.61002 0.64878 -0.24056 -0.08490 -0.14422 630 HOH A O   
4077 O O   . HOH D .   ? 0.46306 0.91841 0.65699 0.27068  0.19856  0.39318  631 HOH A O   
4078 O O   . HOH D .   ? 0.75218 0.43333 1.01488 -0.03307 -0.38397 0.07538  632 HOH A O   
4079 O O   . HOH D .   ? 0.14310 0.44046 0.29435 -0.01474 -0.07655 0.00071  633 HOH A O   
4080 O O   . HOH D .   ? 0.80932 0.46407 0.57984 0.08089  0.10084  0.13366  634 HOH A O   
4081 O O   . HOH D .   ? 0.84700 0.51293 0.60520 -0.22851 0.32824  -0.24289 635 HOH A O   
4082 O O   . HOH D .   ? 0.88616 0.49790 0.60257 0.14326  -0.36512 0.03964  636 HOH A O   
4083 O O   . HOH D .   ? 0.40454 0.87294 0.99723 -0.19063 0.12517  0.09070  637 HOH A O   
# 
