data_8Q81
# 
_entry.id   8Q81 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Q81         pdb_00008q81 10.2210/pdb8q81/pdb 
WWPDB D_1292132797 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-05 ? 
2 'Structure model' 1 1 2025-06-11 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.country'                 
2 2 'Structure model' '_citation.journal_abbrev'          
3 2 'Structure model' '_citation.journal_id_CSD'          
4 2 'Structure model' '_citation.journal_id_ISSN'         
5 2 'Structure model' '_citation.pdbx_database_id_DOI'    
6 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
7 2 'Structure model' '_citation.title'                   
8 2 'Structure model' '_citation.year'                    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Q81 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              michaw@chemi.muni.cz 
_pdbx_contact_author.name_first         Michaela 
_pdbx_contact_author.name_last          Wimmerova 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7108-4198 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Melicher, F.'  1 0000-0002-2296-798X 
'Houser, J.'    2 0000-0003-4504-3891 
'Paulenova, E.' 3 0000-0001-6432-1696 
'Wimmerova, M.' 4 0000-0002-7108-4198 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Glycobiology 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            9999 
_citation.journal_id_ISSN           1460-2423 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;The insight into the biology of five homologous lectins produced by the entomopathogenic bacterium and nematode symbiont Photorhabdus laumondii.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/glycob/cwaf033 
_citation.pdbx_database_id_PubMed   40459235 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Paulenova, E.' 1 ? 
primary 'Dobes, P.'     2 ? 
primary 'Melicher, F.'  3 ? 
primary 'Houser, J.'    4 ? 
primary 'Faltinek, L.'  5 ? 
primary 'Hyrsl, P.'     6 ? 
primary 'Wimmerova, M.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 3/17' 40509.156 1   ? ? ? ? 
2 non-polymer syn 'methyl alpha-L-fucopyranoside'                                               178.183   4   ? ? ? ? 
3 non-polymer syn 1,2-ETHANEDIOL                                                                62.068    3   ? ? ? ? 
4 non-polymer syn 'DI(HYDROXYETHYL)ETHER'                                                       106.120   1   ? ? ? ? 
5 water       nat water                                                                         18.015    221 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKKESINTSGPDNTKSSISDEIEISNEISWTALSGVISAANNADGRLEVFGVGTNNAVWHNWQTVPNTGSSWSGWHSLNE
GATSKPAVHINSDGRLEVFVRGTDNALWHNWQTVPGAGWSGWQSLGGQITSNPVVYINSDGRLEVFARGADNALWHIWQT
APHAGPWSNWQSLNGVLTSDPTVYVNASGRPEVFARSNDYSLWYIKQTASHTYPWTNWQSLSGVITSNPVVISNSDGRLE
VFARGSDNALWHIWQVAPNAGWTNWRSLSGIITSDPAVHINADGRLEVFARGPDNALWHIWQTATSDAWSEWTSLSGVIT
SAPTVAKNSDGWLEVFARGANNALCHIQQTTSSWSTWTSLGGNLIDASAIK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKKESINTSGPDNTKSSISDEIEISNEISWTALSGVISAANNADGRLEVFGVGTNNAVWHNWQTVPNTGSSWSGWHSLNE
GATSKPAVHINSDGRLEVFVRGTDNALWHNWQTVPGAGWSGWQSLGGQITSNPVVYINSDGRLEVFARGADNALWHIWQT
APHAGPWSNWQSLNGVLTSDPTVYVNASGRPEVFARSNDYSLWYIKQTASHTYPWTNWQSLSGVITSNPVVISNSDGRLE
VFARGSDNALWHIWQVAPNAGWTNWRSLSGIITSDPAVHINADGRLEVFARGPDNALWHIWQTATSDAWSEWTSLSGVIT
SAPTVAKNSDGWLEVFARGANNALCHIQQTTSSWSTWTSLGGNLIDASAIK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'methyl alpha-L-fucopyranoside' MFU 
3 1,2-ETHANEDIOL                  EDO 
4 'DI(HYDROXYETHYL)ETHER'         PEG 
5 water                           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LYS n 
1 4   GLU n 
1 5   SER n 
1 6   ILE n 
1 7   ASN n 
1 8   THR n 
1 9   SER n 
1 10  GLY n 
1 11  PRO n 
1 12  ASP n 
1 13  ASN n 
1 14  THR n 
1 15  LYS n 
1 16  SER n 
1 17  SER n 
1 18  ILE n 
1 19  SER n 
1 20  ASP n 
1 21  GLU n 
1 22  ILE n 
1 23  GLU n 
1 24  ILE n 
1 25  SER n 
1 26  ASN n 
1 27  GLU n 
1 28  ILE n 
1 29  SER n 
1 30  TRP n 
1 31  THR n 
1 32  ALA n 
1 33  LEU n 
1 34  SER n 
1 35  GLY n 
1 36  VAL n 
1 37  ILE n 
1 38  SER n 
1 39  ALA n 
1 40  ALA n 
1 41  ASN n 
1 42  ASN n 
1 43  ALA n 
1 44  ASP n 
1 45  GLY n 
1 46  ARG n 
1 47  LEU n 
1 48  GLU n 
1 49  VAL n 
1 50  PHE n 
1 51  GLY n 
1 52  VAL n 
1 53  GLY n 
1 54  THR n 
1 55  ASN n 
1 56  ASN n 
1 57  ALA n 
1 58  VAL n 
1 59  TRP n 
1 60  HIS n 
1 61  ASN n 
1 62  TRP n 
1 63  GLN n 
1 64  THR n 
1 65  VAL n 
1 66  PRO n 
1 67  ASN n 
1 68  THR n 
1 69  GLY n 
1 70  SER n 
1 71  SER n 
1 72  TRP n 
1 73  SER n 
1 74  GLY n 
1 75  TRP n 
1 76  HIS n 
1 77  SER n 
1 78  LEU n 
1 79  ASN n 
1 80  GLU n 
1 81  GLY n 
1 82  ALA n 
1 83  THR n 
1 84  SER n 
1 85  LYS n 
1 86  PRO n 
1 87  ALA n 
1 88  VAL n 
1 89  HIS n 
1 90  ILE n 
1 91  ASN n 
1 92  SER n 
1 93  ASP n 
1 94  GLY n 
1 95  ARG n 
1 96  LEU n 
1 97  GLU n 
1 98  VAL n 
1 99  PHE n 
1 100 VAL n 
1 101 ARG n 
1 102 GLY n 
1 103 THR n 
1 104 ASP n 
1 105 ASN n 
1 106 ALA n 
1 107 LEU n 
1 108 TRP n 
1 109 HIS n 
1 110 ASN n 
1 111 TRP n 
1 112 GLN n 
1 113 THR n 
1 114 VAL n 
1 115 PRO n 
1 116 GLY n 
1 117 ALA n 
1 118 GLY n 
1 119 TRP n 
1 120 SER n 
1 121 GLY n 
1 122 TRP n 
1 123 GLN n 
1 124 SER n 
1 125 LEU n 
1 126 GLY n 
1 127 GLY n 
1 128 GLN n 
1 129 ILE n 
1 130 THR n 
1 131 SER n 
1 132 ASN n 
1 133 PRO n 
1 134 VAL n 
1 135 VAL n 
1 136 TYR n 
1 137 ILE n 
1 138 ASN n 
1 139 SER n 
1 140 ASP n 
1 141 GLY n 
1 142 ARG n 
1 143 LEU n 
1 144 GLU n 
1 145 VAL n 
1 146 PHE n 
1 147 ALA n 
1 148 ARG n 
1 149 GLY n 
1 150 ALA n 
1 151 ASP n 
1 152 ASN n 
1 153 ALA n 
1 154 LEU n 
1 155 TRP n 
1 156 HIS n 
1 157 ILE n 
1 158 TRP n 
1 159 GLN n 
1 160 THR n 
1 161 ALA n 
1 162 PRO n 
1 163 HIS n 
1 164 ALA n 
1 165 GLY n 
1 166 PRO n 
1 167 TRP n 
1 168 SER n 
1 169 ASN n 
1 170 TRP n 
1 171 GLN n 
1 172 SER n 
1 173 LEU n 
1 174 ASN n 
1 175 GLY n 
1 176 VAL n 
1 177 LEU n 
1 178 THR n 
1 179 SER n 
1 180 ASP n 
1 181 PRO n 
1 182 THR n 
1 183 VAL n 
1 184 TYR n 
1 185 VAL n 
1 186 ASN n 
1 187 ALA n 
1 188 SER n 
1 189 GLY n 
1 190 ARG n 
1 191 PRO n 
1 192 GLU n 
1 193 VAL n 
1 194 PHE n 
1 195 ALA n 
1 196 ARG n 
1 197 SER n 
1 198 ASN n 
1 199 ASP n 
1 200 TYR n 
1 201 SER n 
1 202 LEU n 
1 203 TRP n 
1 204 TYR n 
1 205 ILE n 
1 206 LYS n 
1 207 GLN n 
1 208 THR n 
1 209 ALA n 
1 210 SER n 
1 211 HIS n 
1 212 THR n 
1 213 TYR n 
1 214 PRO n 
1 215 TRP n 
1 216 THR n 
1 217 ASN n 
1 218 TRP n 
1 219 GLN n 
1 220 SER n 
1 221 LEU n 
1 222 SER n 
1 223 GLY n 
1 224 VAL n 
1 225 ILE n 
1 226 THR n 
1 227 SER n 
1 228 ASN n 
1 229 PRO n 
1 230 VAL n 
1 231 VAL n 
1 232 ILE n 
1 233 SER n 
1 234 ASN n 
1 235 SER n 
1 236 ASP n 
1 237 GLY n 
1 238 ARG n 
1 239 LEU n 
1 240 GLU n 
1 241 VAL n 
1 242 PHE n 
1 243 ALA n 
1 244 ARG n 
1 245 GLY n 
1 246 SER n 
1 247 ASP n 
1 248 ASN n 
1 249 ALA n 
1 250 LEU n 
1 251 TRP n 
1 252 HIS n 
1 253 ILE n 
1 254 TRP n 
1 255 GLN n 
1 256 VAL n 
1 257 ALA n 
1 258 PRO n 
1 259 ASN n 
1 260 ALA n 
1 261 GLY n 
1 262 TRP n 
1 263 THR n 
1 264 ASN n 
1 265 TRP n 
1 266 ARG n 
1 267 SER n 
1 268 LEU n 
1 269 SER n 
1 270 GLY n 
1 271 ILE n 
1 272 ILE n 
1 273 THR n 
1 274 SER n 
1 275 ASP n 
1 276 PRO n 
1 277 ALA n 
1 278 VAL n 
1 279 HIS n 
1 280 ILE n 
1 281 ASN n 
1 282 ALA n 
1 283 ASP n 
1 284 GLY n 
1 285 ARG n 
1 286 LEU n 
1 287 GLU n 
1 288 VAL n 
1 289 PHE n 
1 290 ALA n 
1 291 ARG n 
1 292 GLY n 
1 293 PRO n 
1 294 ASP n 
1 295 ASN n 
1 296 ALA n 
1 297 LEU n 
1 298 TRP n 
1 299 HIS n 
1 300 ILE n 
1 301 TRP n 
1 302 GLN n 
1 303 THR n 
1 304 ALA n 
1 305 THR n 
1 306 SER n 
1 307 ASP n 
1 308 ALA n 
1 309 TRP n 
1 310 SER n 
1 311 GLU n 
1 312 TRP n 
1 313 THR n 
1 314 SER n 
1 315 LEU n 
1 316 SER n 
1 317 GLY n 
1 318 VAL n 
1 319 ILE n 
1 320 THR n 
1 321 SER n 
1 322 ALA n 
1 323 PRO n 
1 324 THR n 
1 325 VAL n 
1 326 ALA n 
1 327 LYS n 
1 328 ASN n 
1 329 SER n 
1 330 ASP n 
1 331 GLY n 
1 332 TRP n 
1 333 LEU n 
1 334 GLU n 
1 335 VAL n 
1 336 PHE n 
1 337 ALA n 
1 338 ARG n 
1 339 GLY n 
1 340 ALA n 
1 341 ASN n 
1 342 ASN n 
1 343 ALA n 
1 344 LEU n 
1 345 CYS n 
1 346 HIS n 
1 347 ILE n 
1 348 GLN n 
1 349 GLN n 
1 350 THR n 
1 351 THR n 
1 352 SER n 
1 353 SER n 
1 354 TRP n 
1 355 SER n 
1 356 THR n 
1 357 TRP n 
1 358 THR n 
1 359 SER n 
1 360 LEU n 
1 361 GLY n 
1 362 GLY n 
1 363 ASN n 
1 364 LEU n 
1 365 ILE n 
1 366 ASP n 
1 367 ALA n 
1 368 SER n 
1 369 ALA n 
1 370 ILE n 
1 371 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   371 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 plu0735 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Photorhabdus laumondii subsp. laumondii TTO1' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     243265 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                 ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                        ? 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL                  'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE                       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                 ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                      ? 'C5 H11 N O2 S'  149.211 
MFU L-saccharide        n 'methyl alpha-L-fucopyranoside' 
'ALPHA-L-METHYL-FUCOSE; methyl 6-deoxy-alpha-L-galactopyranoside; methyl alpha-L-fucoside; methyl L-fucoside; methyl fucoside' 
'C7 H14 O5'      178.183 
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER'         ? 'C4 H10 O3'      106.120 
PHE 'L-peptide linking' y PHENYLALANINE                   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
MFU 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 'LFucp[1Me]a'             
MFU 'COMMON NAME'                         GMML     1.0 1-methyl-a-L-fucopyranose 
MFU 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 o1-methyl-a-L-fucose      
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   ILE 6   6   ?   ?   ?   A . n 
A 1 7   ASN 7   7   ?   ?   ?   A . n 
A 1 8   THR 8   8   ?   ?   ?   A . n 
A 1 9   SER 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  PRO 11  11  ?   ?   ?   A . n 
A 1 12  ASP 12  12  ?   ?   ?   A . n 
A 1 13  ASN 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  LYS 15  15  ?   ?   ?   A . n 
A 1 16  SER 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  ILE 18  18  ?   ?   ?   A . n 
A 1 19  SER 19  19  ?   ?   ?   A . n 
A 1 20  ASP 20  20  ?   ?   ?   A . n 
A 1 21  GLU 21  21  ?   ?   ?   A . n 
A 1 22  ILE 22  22  ?   ?   ?   A . n 
A 1 23  GLU 23  23  ?   ?   ?   A . n 
A 1 24  ILE 24  24  ?   ?   ?   A . n 
A 1 25  SER 25  25  ?   ?   ?   A . n 
A 1 26  ASN 26  26  ?   ?   ?   A . n 
A 1 27  GLU 27  27  ?   ?   ?   A . n 
A 1 28  ILE 28  28  ?   ?   ?   A . n 
A 1 29  SER 29  29  ?   ?   ?   A . n 
A 1 30  TRP 30  30  30  TRP TRP A . n 
A 1 31  THR 31  31  31  THR THR A . n 
A 1 32  ALA 32  32  32  ALA ALA A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  SER 34  34  34  SER SER A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  ILE 37  37  37  ILE ILE A . n 
A 1 38  SER 38  38  38  SER SER A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  ASN 41  41  41  ASN ASN A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  ALA 43  43  43  ALA ALA A . n 
A 1 44  ASP 44  44  44  ASP ASP A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  ARG 46  46  46  ARG ARG A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  PHE 50  50  50  PHE PHE A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ASN 55  55  55  ASN ASN A . n 
A 1 56  ASN 56  56  56  ASN ASN A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  TRP 59  59  59  TRP TRP A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  TRP 62  62  62  TRP TRP A . n 
A 1 63  GLN 63  63  63  GLN GLN A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  PRO 66  66  66  PRO PRO A . n 
A 1 67  ASN 67  67  67  ASN ASN A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  SER 70  70  70  SER SER A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  TRP 72  72  72  TRP TRP A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  SER 77  77  77  SER SER A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  GLU 80  80  80  GLU GLU A . n 
A 1 81  GLY 81  81  81  GLY GLY A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  THR 83  83  83  THR THR A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  LYS 85  85  85  LYS LYS A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  HIS 89  89  89  HIS HIS A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  ASN 91  91  91  ASN ASN A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  ASP 93  93  93  ASP ASP A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 VAL 100 100 100 VAL VAL A . n 
A 1 101 ARG 101 101 101 ARG ARG A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 ASP 104 104 104 ASP ASP A . n 
A 1 105 ASN 105 105 105 ASN ASN A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 TRP 108 108 108 TRP TRP A . n 
A 1 109 HIS 109 109 109 HIS HIS A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 TRP 111 111 111 TRP TRP A . n 
A 1 112 GLN 112 112 112 GLN GLN A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 TRP 119 119 119 TRP TRP A . n 
A 1 120 SER 120 120 120 SER SER A . n 
A 1 121 GLY 121 121 121 GLY GLY A . n 
A 1 122 TRP 122 122 122 TRP TRP A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 SER 124 124 124 SER SER A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 GLN 128 128 128 GLN GLN A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 ASN 132 132 132 ASN ASN A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 TYR 136 136 136 TYR TYR A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 ASN 138 138 138 ASN ASN A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 ARG 142 142 142 ARG ARG A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 ARG 148 148 148 ARG ARG A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 ASP 151 151 151 ASP ASP A . n 
A 1 152 ASN 152 152 152 ASN ASN A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 TRP 155 155 155 TRP TRP A . n 
A 1 156 HIS 156 156 156 HIS HIS A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 TRP 158 158 158 TRP TRP A . n 
A 1 159 GLN 159 159 159 GLN GLN A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 GLY 165 165 165 GLY GLY A . n 
A 1 166 PRO 166 166 166 PRO PRO A . n 
A 1 167 TRP 167 167 167 TRP TRP A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 ASN 169 169 169 ASN ASN A . n 
A 1 170 TRP 170 170 170 TRP TRP A . n 
A 1 171 GLN 171 171 171 GLN GLN A . n 
A 1 172 SER 172 172 172 SER SER A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 ASN 174 174 174 ASN ASN A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 THR 178 178 178 THR THR A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 TYR 184 184 184 TYR TYR A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 GLY 189 189 189 GLY GLY A . n 
A 1 190 ARG 190 190 190 ARG ARG A . n 
A 1 191 PRO 191 191 191 PRO PRO A . n 
A 1 192 GLU 192 192 192 GLU GLU A . n 
A 1 193 VAL 193 193 193 VAL VAL A . n 
A 1 194 PHE 194 194 194 PHE PHE A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 ARG 196 196 196 ARG ARG A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 ASN 198 198 198 ASN ASN A . n 
A 1 199 ASP 199 199 199 ASP ASP A . n 
A 1 200 TYR 200 200 200 TYR TYR A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 TRP 203 203 203 TRP TRP A . n 
A 1 204 TYR 204 204 204 TYR TYR A . n 
A 1 205 ILE 205 205 205 ILE ILE A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 GLN 207 207 207 GLN GLN A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 ALA 209 209 209 ALA ALA A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 HIS 211 211 211 HIS HIS A . n 
A 1 212 THR 212 212 212 THR THR A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 PRO 214 214 214 PRO PRO A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 THR 216 216 216 THR THR A . n 
A 1 217 ASN 217 217 217 ASN ASN A . n 
A 1 218 TRP 218 218 218 TRP TRP A . n 
A 1 219 GLN 219 219 219 GLN GLN A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 SER 222 222 222 SER SER A . n 
A 1 223 GLY 223 223 223 GLY GLY A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 SER 227 227 227 SER SER A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 PRO 229 229 229 PRO PRO A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 VAL 231 231 231 VAL VAL A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 ASN 234 234 234 ASN ASN A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 ASP 236 236 236 ASP ASP A . n 
A 1 237 GLY 237 237 237 GLY GLY A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 PHE 242 242 242 PHE PHE A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ARG 244 244 244 ARG ARG A . n 
A 1 245 GLY 245 245 245 GLY GLY A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 ASP 247 247 247 ASP ASP A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 TRP 251 251 251 TRP TRP A . n 
A 1 252 HIS 252 252 252 HIS HIS A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 TRP 254 254 254 TRP TRP A . n 
A 1 255 GLN 255 255 255 GLN GLN A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 PRO 258 258 258 PRO PRO A . n 
A 1 259 ASN 259 259 259 ASN ASN A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 GLY 261 261 261 GLY GLY A . n 
A 1 262 TRP 262 262 262 TRP TRP A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 ASN 264 264 264 ASN ASN A . n 
A 1 265 TRP 265 265 265 TRP TRP A . n 
A 1 266 ARG 266 266 266 ARG ARG A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 ILE 272 272 272 ILE ILE A . n 
A 1 273 THR 273 273 273 THR THR A . n 
A 1 274 SER 274 274 274 SER SER A . n 
A 1 275 ASP 275 275 275 ASP ASP A . n 
A 1 276 PRO 276 276 276 PRO PRO A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 VAL 278 278 278 VAL VAL A . n 
A 1 279 HIS 279 279 279 HIS HIS A . n 
A 1 280 ILE 280 280 280 ILE ILE A . n 
A 1 281 ASN 281 281 281 ASN ASN A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 ASP 283 283 283 ASP ASP A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ARG 285 285 285 ARG ARG A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 GLU 287 287 287 GLU GLU A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 PHE 289 289 289 PHE PHE A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 ARG 291 291 291 ARG ARG A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 PRO 293 293 293 PRO PRO A . n 
A 1 294 ASP 294 294 294 ASP ASP A . n 
A 1 295 ASN 295 295 295 ASN ASN A . n 
A 1 296 ALA 296 296 296 ALA ALA A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 TRP 298 298 298 TRP TRP A . n 
A 1 299 HIS 299 299 299 HIS HIS A . n 
A 1 300 ILE 300 300 300 ILE ILE A . n 
A 1 301 TRP 301 301 301 TRP TRP A . n 
A 1 302 GLN 302 302 302 GLN GLN A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 THR 305 305 305 THR THR A . n 
A 1 306 SER 306 306 306 SER SER A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 TRP 309 309 309 TRP TRP A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 GLU 311 311 311 GLU GLU A . n 
A 1 312 TRP 312 312 312 TRP TRP A . n 
A 1 313 THR 313 313 313 THR THR A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 VAL 318 318 318 VAL VAL A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 SER 321 321 321 SER SER A . n 
A 1 322 ALA 322 322 322 ALA ALA A . n 
A 1 323 PRO 323 323 323 PRO PRO A . n 
A 1 324 THR 324 324 324 THR THR A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 LYS 327 327 327 LYS LYS A . n 
A 1 328 ASN 328 328 328 ASN ASN A . n 
A 1 329 SER 329 329 329 SER SER A . n 
A 1 330 ASP 330 330 330 ASP ASP A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 TRP 332 332 332 TRP TRP A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 GLU 334 334 334 GLU GLU A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 ARG 338 338 338 ARG ARG A . n 
A 1 339 GLY 339 339 339 GLY GLY A . n 
A 1 340 ALA 340 340 340 ALA ALA A . n 
A 1 341 ASN 341 341 341 ASN ASN A . n 
A 1 342 ASN 342 342 342 ASN ASN A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 LEU 344 344 344 LEU LEU A . n 
A 1 345 CYS 345 345 345 CYS CYS A . n 
A 1 346 HIS 346 346 346 HIS HIS A . n 
A 1 347 ILE 347 347 347 ILE ILE A . n 
A 1 348 GLN 348 348 348 GLN GLN A . n 
A 1 349 GLN 349 349 349 GLN GLN A . n 
A 1 350 THR 350 350 350 THR THR A . n 
A 1 351 THR 351 351 351 THR THR A . n 
A 1 352 SER 352 352 352 SER SER A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 TRP 354 354 354 TRP TRP A . n 
A 1 355 SER 355 355 355 SER SER A . n 
A 1 356 THR 356 356 356 THR THR A . n 
A 1 357 TRP 357 357 357 TRP TRP A . n 
A 1 358 THR 358 358 358 THR THR A . n 
A 1 359 SER 359 359 359 SER SER A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 LEU 364 364 364 LEU LEU A . n 
A 1 365 ILE 365 365 365 ILE ILE A . n 
A 1 366 ASP 366 366 366 ASP ASP A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 SER 368 368 368 SER SER A . n 
A 1 369 ALA 369 369 369 ALA ALA A . n 
A 1 370 ILE 370 370 370 ILE ILE A . n 
A 1 371 LYS 371 371 371 LYS LYS A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        MFU 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   MFU 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 MFU 1   401 402 MFU MFU A . 
C 2 MFU 1   402 403 MFU MFU A . 
D 2 MFU 1   403 404 MFU MFU A . 
E 2 MFU 1   404 405 MFU MFU A . 
F 3 EDO 1   405 406 EDO EDO A . 
G 3 EDO 1   406 407 EDO EDO A . 
H 3 EDO 1   407 408 EDO EDO A . 
I 4 PEG 1   408 409 PEG PEG A . 
J 5 HOH 1   501 189 HOH HOH A . 
J 5 HOH 2   502 60  HOH HOH A . 
J 5 HOH 3   503 203 HOH HOH A . 
J 5 HOH 4   504 64  HOH HOH A . 
J 5 HOH 5   505 210 HOH HOH A . 
J 5 HOH 6   506 131 HOH HOH A . 
J 5 HOH 7   507 196 HOH HOH A . 
J 5 HOH 8   508 216 HOH HOH A . 
J 5 HOH 9   509 42  HOH HOH A . 
J 5 HOH 10  510 153 HOH HOH A . 
J 5 HOH 11  511 62  HOH HOH A . 
J 5 HOH 12  512 77  HOH HOH A . 
J 5 HOH 13  513 178 HOH HOH A . 
J 5 HOH 14  514 221 HOH HOH A . 
J 5 HOH 15  515 195 HOH HOH A . 
J 5 HOH 16  516 17  HOH HOH A . 
J 5 HOH 17  517 100 HOH HOH A . 
J 5 HOH 18  518 174 HOH HOH A . 
J 5 HOH 19  519 122 HOH HOH A . 
J 5 HOH 20  520 220 HOH HOH A . 
J 5 HOH 21  521 127 HOH HOH A . 
J 5 HOH 22  522 126 HOH HOH A . 
J 5 HOH 23  523 184 HOH HOH A . 
J 5 HOH 24  524 101 HOH HOH A . 
J 5 HOH 25  525 69  HOH HOH A . 
J 5 HOH 26  526 158 HOH HOH A . 
J 5 HOH 27  527 23  HOH HOH A . 
J 5 HOH 28  528 193 HOH HOH A . 
J 5 HOH 29  529 37  HOH HOH A . 
J 5 HOH 30  530 120 HOH HOH A . 
J 5 HOH 31  531 15  HOH HOH A . 
J 5 HOH 32  532 155 HOH HOH A . 
J 5 HOH 33  533 89  HOH HOH A . 
J 5 HOH 34  534 19  HOH HOH A . 
J 5 HOH 35  535 39  HOH HOH A . 
J 5 HOH 36  536 2   HOH HOH A . 
J 5 HOH 37  537 136 HOH HOH A . 
J 5 HOH 38  538 169 HOH HOH A . 
J 5 HOH 39  539 207 HOH HOH A . 
J 5 HOH 40  540 119 HOH HOH A . 
J 5 HOH 41  541 65  HOH HOH A . 
J 5 HOH 42  542 157 HOH HOH A . 
J 5 HOH 43  543 114 HOH HOH A . 
J 5 HOH 44  544 121 HOH HOH A . 
J 5 HOH 45  545 104 HOH HOH A . 
J 5 HOH 46  546 208 HOH HOH A . 
J 5 HOH 47  547 22  HOH HOH A . 
J 5 HOH 48  548 137 HOH HOH A . 
J 5 HOH 49  549 167 HOH HOH A . 
J 5 HOH 50  550 6   HOH HOH A . 
J 5 HOH 51  551 8   HOH HOH A . 
J 5 HOH 52  552 68  HOH HOH A . 
J 5 HOH 53  553 183 HOH HOH A . 
J 5 HOH 54  554 132 HOH HOH A . 
J 5 HOH 55  555 73  HOH HOH A . 
J 5 HOH 56  556 115 HOH HOH A . 
J 5 HOH 57  557 12  HOH HOH A . 
J 5 HOH 58  558 141 HOH HOH A . 
J 5 HOH 59  559 194 HOH HOH A . 
J 5 HOH 60  560 45  HOH HOH A . 
J 5 HOH 61  561 52  HOH HOH A . 
J 5 HOH 62  562 151 HOH HOH A . 
J 5 HOH 63  563 156 HOH HOH A . 
J 5 HOH 64  564 54  HOH HOH A . 
J 5 HOH 65  565 190 HOH HOH A . 
J 5 HOH 66  566 90  HOH HOH A . 
J 5 HOH 67  567 128 HOH HOH A . 
J 5 HOH 68  568 53  HOH HOH A . 
J 5 HOH 69  569 107 HOH HOH A . 
J 5 HOH 70  570 48  HOH HOH A . 
J 5 HOH 71  571 36  HOH HOH A . 
J 5 HOH 72  572 63  HOH HOH A . 
J 5 HOH 73  573 9   HOH HOH A . 
J 5 HOH 74  574 14  HOH HOH A . 
J 5 HOH 75  575 116 HOH HOH A . 
J 5 HOH 76  576 182 HOH HOH A . 
J 5 HOH 77  577 133 HOH HOH A . 
J 5 HOH 78  578 46  HOH HOH A . 
J 5 HOH 79  579 32  HOH HOH A . 
J 5 HOH 80  580 94  HOH HOH A . 
J 5 HOH 81  581 149 HOH HOH A . 
J 5 HOH 82  582 75  HOH HOH A . 
J 5 HOH 83  583 162 HOH HOH A . 
J 5 HOH 84  584 147 HOH HOH A . 
J 5 HOH 85  585 130 HOH HOH A . 
J 5 HOH 86  586 30  HOH HOH A . 
J 5 HOH 87  587 43  HOH HOH A . 
J 5 HOH 88  588 7   HOH HOH A . 
J 5 HOH 89  589 58  HOH HOH A . 
J 5 HOH 90  590 56  HOH HOH A . 
J 5 HOH 91  591 187 HOH HOH A . 
J 5 HOH 92  592 18  HOH HOH A . 
J 5 HOH 93  593 171 HOH HOH A . 
J 5 HOH 94  594 117 HOH HOH A . 
J 5 HOH 95  595 192 HOH HOH A . 
J 5 HOH 96  596 170 HOH HOH A . 
J 5 HOH 97  597 163 HOH HOH A . 
J 5 HOH 98  598 29  HOH HOH A . 
J 5 HOH 99  599 209 HOH HOH A . 
J 5 HOH 100 600 27  HOH HOH A . 
J 5 HOH 101 601 1   HOH HOH A . 
J 5 HOH 102 602 47  HOH HOH A . 
J 5 HOH 103 603 50  HOH HOH A . 
J 5 HOH 104 604 83  HOH HOH A . 
J 5 HOH 105 605 219 HOH HOH A . 
J 5 HOH 106 606 35  HOH HOH A . 
J 5 HOH 107 607 34  HOH HOH A . 
J 5 HOH 108 608 105 HOH HOH A . 
J 5 HOH 109 609 164 HOH HOH A . 
J 5 HOH 110 610 113 HOH HOH A . 
J 5 HOH 111 611 202 HOH HOH A . 
J 5 HOH 112 612 71  HOH HOH A . 
J 5 HOH 113 613 61  HOH HOH A . 
J 5 HOH 114 614 55  HOH HOH A . 
J 5 HOH 115 615 111 HOH HOH A . 
J 5 HOH 116 616 41  HOH HOH A . 
J 5 HOH 117 617 109 HOH HOH A . 
J 5 HOH 118 618 96  HOH HOH A . 
J 5 HOH 119 619 142 HOH HOH A . 
J 5 HOH 120 620 176 HOH HOH A . 
J 5 HOH 121 621 31  HOH HOH A . 
J 5 HOH 122 622 129 HOH HOH A . 
J 5 HOH 123 623 106 HOH HOH A . 
J 5 HOH 124 624 201 HOH HOH A . 
J 5 HOH 125 625 145 HOH HOH A . 
J 5 HOH 126 626 72  HOH HOH A . 
J 5 HOH 127 627 217 HOH HOH A . 
J 5 HOH 128 628 57  HOH HOH A . 
J 5 HOH 129 629 40  HOH HOH A . 
J 5 HOH 130 630 97  HOH HOH A . 
J 5 HOH 131 631 124 HOH HOH A . 
J 5 HOH 132 632 166 HOH HOH A . 
J 5 HOH 133 633 200 HOH HOH A . 
J 5 HOH 134 634 185 HOH HOH A . 
J 5 HOH 135 635 49  HOH HOH A . 
J 5 HOH 136 636 103 HOH HOH A . 
J 5 HOH 137 637 159 HOH HOH A . 
J 5 HOH 138 638 123 HOH HOH A . 
J 5 HOH 139 639 38  HOH HOH A . 
J 5 HOH 140 640 215 HOH HOH A . 
J 5 HOH 141 641 16  HOH HOH A . 
J 5 HOH 142 642 172 HOH HOH A . 
J 5 HOH 143 643 173 HOH HOH A . 
J 5 HOH 144 644 102 HOH HOH A . 
J 5 HOH 145 645 86  HOH HOH A . 
J 5 HOH 146 646 199 HOH HOH A . 
J 5 HOH 147 647 165 HOH HOH A . 
J 5 HOH 148 648 67  HOH HOH A . 
J 5 HOH 149 649 85  HOH HOH A . 
J 5 HOH 150 650 143 HOH HOH A . 
J 5 HOH 151 651 3   HOH HOH A . 
J 5 HOH 152 652 44  HOH HOH A . 
J 5 HOH 153 653 28  HOH HOH A . 
J 5 HOH 154 654 98  HOH HOH A . 
J 5 HOH 155 655 154 HOH HOH A . 
J 5 HOH 156 656 26  HOH HOH A . 
J 5 HOH 157 657 4   HOH HOH A . 
J 5 HOH 158 658 81  HOH HOH A . 
J 5 HOH 159 659 179 HOH HOH A . 
J 5 HOH 160 660 91  HOH HOH A . 
J 5 HOH 161 661 99  HOH HOH A . 
J 5 HOH 162 662 191 HOH HOH A . 
J 5 HOH 163 663 138 HOH HOH A . 
J 5 HOH 164 664 70  HOH HOH A . 
J 5 HOH 165 665 150 HOH HOH A . 
J 5 HOH 166 666 177 HOH HOH A . 
J 5 HOH 167 667 10  HOH HOH A . 
J 5 HOH 168 668 74  HOH HOH A . 
J 5 HOH 169 669 134 HOH HOH A . 
J 5 HOH 170 670 186 HOH HOH A . 
J 5 HOH 171 671 5   HOH HOH A . 
J 5 HOH 172 672 21  HOH HOH A . 
J 5 HOH 173 673 59  HOH HOH A . 
J 5 HOH 174 674 66  HOH HOH A . 
J 5 HOH 175 675 11  HOH HOH A . 
J 5 HOH 176 676 93  HOH HOH A . 
J 5 HOH 177 677 20  HOH HOH A . 
J 5 HOH 178 678 188 HOH HOH A . 
J 5 HOH 179 679 88  HOH HOH A . 
J 5 HOH 180 680 206 HOH HOH A . 
J 5 HOH 181 681 95  HOH HOH A . 
J 5 HOH 182 682 25  HOH HOH A . 
J 5 HOH 183 683 78  HOH HOH A . 
J 5 HOH 184 684 175 HOH HOH A . 
J 5 HOH 185 685 118 HOH HOH A . 
J 5 HOH 186 686 87  HOH HOH A . 
J 5 HOH 187 687 160 HOH HOH A . 
J 5 HOH 188 688 82  HOH HOH A . 
J 5 HOH 189 689 79  HOH HOH A . 
J 5 HOH 190 690 180 HOH HOH A . 
J 5 HOH 191 691 148 HOH HOH A . 
J 5 HOH 192 692 110 HOH HOH A . 
J 5 HOH 193 693 152 HOH HOH A . 
J 5 HOH 194 694 144 HOH HOH A . 
J 5 HOH 195 695 24  HOH HOH A . 
J 5 HOH 196 696 76  HOH HOH A . 
J 5 HOH 197 697 112 HOH HOH A . 
J 5 HOH 198 698 168 HOH HOH A . 
J 5 HOH 199 699 161 HOH HOH A . 
J 5 HOH 200 700 33  HOH HOH A . 
J 5 HOH 201 701 84  HOH HOH A . 
J 5 HOH 202 702 197 HOH HOH A . 
J 5 HOH 203 703 198 HOH HOH A . 
J 5 HOH 204 704 181 HOH HOH A . 
J 5 HOH 205 705 204 HOH HOH A . 
J 5 HOH 206 706 139 HOH HOH A . 
J 5 HOH 207 707 13  HOH HOH A . 
J 5 HOH 208 708 92  HOH HOH A . 
J 5 HOH 209 709 212 HOH HOH A . 
J 5 HOH 210 710 211 HOH HOH A . 
J 5 HOH 211 711 218 HOH HOH A . 
J 5 HOH 212 712 205 HOH HOH A . 
J 5 HOH 213 713 214 HOH HOH A . 
J 5 HOH 214 714 213 HOH HOH A . 
J 5 HOH 215 715 80  HOH HOH A . 
J 5 HOH 216 716 125 HOH HOH A . 
J 5 HOH 217 717 135 HOH HOH A . 
J 5 HOH 218 718 51  HOH HOH A . 
J 5 HOH 219 719 146 HOH HOH A . 
J 5 HOH 220 720 108 HOH HOH A . 
J 5 HOH 221 721 140 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A GLU 80  ? CG  ? A GLU 80  CG  
2 1 Y 1 A GLU 80  ? CD  ? A GLU 80  CD  
3 1 Y 1 A GLU 80  ? OE1 ? A GLU 80  OE1 
4 1 Y 1 A GLU 80  ? OE2 ? A GLU 80  OE2 
5 1 Y 1 A LYS 371 ? C   ? A LYS 371 C   
6 1 Y 1 A LYS 371 ? O   ? A LYS 371 O   
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALA  ? ? ? 3.3.22   3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? 2.8.3    4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Q81 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     56.611 
_cell.length_a_esd                 ? 
_cell.length_b                     69.620 
_cell.length_b_esd                 ? 
_cell.length_c                     76.245 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Q81 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Q81 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.85 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          33.68 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;90 m HEPES, 
9% PEG 8000
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-11-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9763 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9763 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P13 (MX1)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8Q81 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.5 
_reflns.d_resolution_low                               76.25 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     48191 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.5 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.101 
_reflns.pdbx_Rpim_I_all                                0.027 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.097 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.50 
_reflns_shell.d_res_low                                     1.58 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.8 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             6850 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.2 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.830 
_reflns_shell.pdbx_Rpim_I_all                               0.225 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.897 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          97.2 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.798 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.794 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            -0.784 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            1.578 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               15.308 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.971 
_refine.correlation_coeff_Fo_to_Fc_free          0.956 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8Q81 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.500 
_refine.ls_d_res_low                             76.25 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     48140 
_refine.ls_number_reflns_R_free                  2382 
_refine.ls_number_reflns_R_work                  45758 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.331 
_refine.ls_percent_reflns_R_free                 4.948 
_refine.ls_R_factor_all                          0.162 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1868 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1603 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.073 
_refine.pdbx_overall_ESU_R_Free                  0.073 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.320 
_refine.overall_SU_ML                            0.049 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        2647 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         67 
_refine_hist.number_atoms_solvent             221 
_refine_hist.number_atoms_total               2935 
_refine_hist.d_res_high                       1.500 
_refine_hist.d_res_low                        76.25 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.011  2830 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2473 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.516  1.631  3897 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.564  1.595  5661 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 8.042  5.000  351  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 7.320  5.000  13   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.358 10.000 364  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 17.653 10.000 127  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.082  0.200  427  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  3522 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  720  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.174  0.200  451  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.193  0.200  2329 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.178  0.200  1427 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.089  0.200  1466 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.111  0.200  182  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.154  0.200  4    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.171  0.200  45   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.172  0.200  21   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.486  1.507  1384 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.486  1.509  1385 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.210  2.705  1735 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.213  2.707  1736 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.225  1.701  1446 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.224  1.702  1447 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.244  3.022  2160 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.244  3.023  2161 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 4.240  17.175 3229 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.154  16.440 3183 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.500 1.539  3571 . 178 3282 96.8916 . 0.208 . . 0.207 . . . . . 0.185 . 20 . 0.965 0.958 0.237 
'X-RAY DIFFRACTION' 1.539 1.581  3488 . 164 3218 96.9610 . 0.191 . . 0.189 . . . . . 0.167 . 20 . 0.972 0.965 0.230 
'X-RAY DIFFRACTION' 1.581 1.627  3373 . 148 3136 97.3614 . 0.182 . . 0.182 . . . . . 0.160 . 20 . 0.975 0.973 0.188 
'X-RAY DIFFRACTION' 1.627 1.677  3265 . 156 3030 97.5804 . 0.191 . . 0.188 . . . . . 0.164 . 20 . 0.974 0.955 0.245 
'X-RAY DIFFRACTION' 1.677 1.732  3230 . 130 3026 97.7090 . 0.170 . . 0.167 . . . . . 0.146 . 20 . 0.981 0.969 0.242 
'X-RAY DIFFRACTION' 1.732 1.793  3087 . 163 2861 97.9592 . 0.158 . . 0.155 . . . . . 0.136 . 20 . 0.984 0.976 0.202 
'X-RAY DIFFRACTION' 1.793 1.860  2974 . 153 2771 98.3188 . 0.156 . . 0.155 . . . . . 0.138 . 20 . 0.984 0.983 0.172 
'X-RAY DIFFRACTION' 1.860 1.936  2891 . 126 2705 97.9246 . 0.154 . . 0.153 . . . . . 0.135 . 20 . 0.985 0.977 0.185 
'X-RAY DIFFRACTION' 1.936 2.022  2777 . 144 2603 98.9197 . 0.151 . . 0.149 . . . . . 0.134 . 20 . 0.986 0.979 0.187 
'X-RAY DIFFRACTION' 2.022 2.120  2639 . 115 2479 98.2948 . 0.161 . . 0.159 . . . . . 0.145 . 20 . 0.985 0.978 0.192 
'X-RAY DIFFRACTION' 2.120 2.235  2520 . 147 2350 99.0873 . 0.159 . . 0.157 . . . . . 0.144 . 20 . 0.985 0.976 0.192 
'X-RAY DIFFRACTION' 2.235 2.370  2402 . 112 2266 99.0008 . 0.157 . . 0.156 . . . . . 0.144 . 20 . 0.985 0.982 0.169 
'X-RAY DIFFRACTION' 2.370 2.533  2240 . 126 2093 99.0625 . 0.148 . . 0.147 . . . . . 0.137 . 20 . 0.987 0.984 0.155 
'X-RAY DIFFRACTION' 2.533 2.736  2129 . 113 2001 99.2954 . 0.151 . . 0.151 . . . . . 0.141 . 20 . 0.987 0.987 0.148 
'X-RAY DIFFRACTION' 2.736 2.996  1944 . 92  1842 99.4856 . 0.159 . . 0.158 . . . . . 0.152 . 20 . 0.985 0.983 0.176 
'X-RAY DIFFRACTION' 2.996 3.348  1777 . 82  1687 99.5498 . 0.160 . . 0.160 . . . . . 0.158 . 20 . 0.985 0.979 0.171 
'X-RAY DIFFRACTION' 3.348 3.864  1576 . 88  1485 99.8096 . 0.171 . . 0.169 . . . . . 0.168 . 20 . 0.983 0.979 0.209 
'X-RAY DIFFRACTION' 3.864 4.725  1365 . 65  1298 99.8535 . 0.136 . . 0.135 . . . . . 0.140 . 20 . 0.990 0.989 0.155 
'X-RAY DIFFRACTION' 4.725 6.655  1056 . 49  1006 99.9053 . 0.161 . . 0.161 . . . . . 0.166 . 20 . 0.988 0.987 0.165 
'X-RAY DIFFRACTION' 6.655 51.412 653  . 31  619  99.5406 . 0.213 . . 0.208 . . . . . 0.207 . 20 . 0.969 0.944 0.315 
# 
_struct.entry_id                     8Q81 
_struct.title                        'Photorhabdus laumondii lectin PLL3 in complex with alpha-methyl-fucoside' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Q81 
_struct_keywords.text            'lectin, saccharide binding protein, seven-bladed beta-propeller, CELL ADHESION' 
_struct_keywords.pdbx_keywords   'CELL ADHESION' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 4 ? 
J N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q7N8I7_PHOLL 
_struct_ref.pdbx_db_accession          Q7N8I7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKKESINTSGPDNTKSSISDEIEISNEISWTALSGVISAANNADGRLEVFGVGTNNAVWHNWQTVPNTGSSWSGWHSLNE
GATSKPAVHINSDGRLEVFVRGTDNALWHNWQTVPGAGWSGWQSLGGQITSNPVVYINSDGRLEVFARGADNALWHIWQT
APHAGPWSNWQSLNGVLTSDPTVYVNASGRPEVFARSNDYSLWYIKQTASHTYPWTNWQSLSGVITSNPVVISNSDGRLE
VFARGSDNALWHIWQVAPNAGWTNWRSLSGIITSDPAVHINADGRLEVFARGPDNALWHIWQTATSDAWSEWTSLSGVIT
SAPTVAKNSDGWLEVFARGANNALCHIQQTTSSWSTWTSLGGNLIDASAIK
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8Q81 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 371 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q7N8I7 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  371 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       371 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2340  ? 
1 MORE         20    ? 
1 'SSA (A^2)'  12860 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'mass spectrometry' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           165 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            165 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    166 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     166 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       6.03 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 37  ? ASN A 41  ? ILE A 37  ASN A 41  
AA1 2 LEU A 47  ? GLY A 53  ? LEU A 47  GLY A 53  
AA1 3 VAL A 58  ? TRP A 62  ? VAL A 58  TRP A 62  
AA1 4 HIS A 76  ? SER A 77  ? HIS A 76  SER A 77  
AA2 1 ILE A 37  ? ASN A 41  ? ILE A 37  ASN A 41  
AA2 2 LEU A 47  ? GLY A 53  ? LEU A 47  GLY A 53  
AA2 3 LEU A 364 ? ILE A 365 ? LEU A 364 ILE A 365 
AA3 1 ALA A 87  ? ILE A 90  ? ALA A 87  ILE A 90  
AA3 2 LEU A 96  ? ARG A 101 ? LEU A 96  ARG A 101 
AA3 3 LEU A 107 ? VAL A 114 ? LEU A 107 VAL A 114 
AA3 4 ALA A 117 ? TRP A 119 ? ALA A 117 TRP A 119 
AA4 1 ALA A 87  ? ILE A 90  ? ALA A 87  ILE A 90  
AA4 2 LEU A 96  ? ARG A 101 ? LEU A 96  ARG A 101 
AA4 3 LEU A 107 ? VAL A 114 ? LEU A 107 VAL A 114 
AA4 4 GLN A 123 ? GLY A 126 ? GLN A 123 GLY A 126 
AA5 1 VAL A 134 ? ILE A 137 ? VAL A 134 ILE A 137 
AA5 2 LEU A 143 ? ARG A 148 ? LEU A 143 ARG A 148 
AA5 3 LEU A 154 ? ALA A 161 ? LEU A 154 ALA A 161 
AA5 4 ALA A 164 ? TRP A 167 ? ALA A 164 TRP A 167 
AA6 1 VAL A 134 ? ILE A 137 ? VAL A 134 ILE A 137 
AA6 2 LEU A 143 ? ARG A 148 ? LEU A 143 ARG A 148 
AA6 3 LEU A 154 ? ALA A 161 ? LEU A 154 ALA A 161 
AA6 4 GLN A 171 ? SER A 172 ? GLN A 171 SER A 172 
AA7 1 THR A 182 ? VAL A 185 ? THR A 182 VAL A 185 
AA7 2 PRO A 191 ? ARG A 196 ? PRO A 191 ARG A 196 
AA7 3 LEU A 202 ? LYS A 206 ? LEU A 202 LYS A 206 
AA7 4 GLN A 219 ? SER A 220 ? GLN A 219 SER A 220 
AA8 1 VAL A 230 ? SER A 233 ? VAL A 230 SER A 233 
AA8 2 LEU A 239 ? ARG A 244 ? LEU A 239 ARG A 244 
AA8 3 LEU A 250 ? TRP A 254 ? LEU A 250 TRP A 254 
AA8 4 ARG A 266 ? SER A 267 ? ARG A 266 SER A 267 
AA9 1 ALA A 277 ? ILE A 280 ? ALA A 277 ILE A 280 
AA9 2 LEU A 286 ? ARG A 291 ? LEU A 286 ARG A 291 
AA9 3 LEU A 297 ? TRP A 301 ? LEU A 297 TRP A 301 
AA9 4 THR A 313 ? SER A 314 ? THR A 313 SER A 314 
AB1 1 THR A 324 ? LYS A 327 ? THR A 324 LYS A 327 
AB1 2 LEU A 333 ? ARG A 338 ? LEU A 333 ARG A 338 
AB1 3 LEU A 344 ? GLN A 348 ? LEU A 344 GLN A 348 
AB1 4 THR A 358 ? SER A 359 ? THR A 358 SER A 359 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 38  ? N SER A 38  O PHE A 50  ? O PHE A 50  
AA1 2 3 N VAL A 49  ? N VAL A 49  O ASN A 61  ? O ASN A 61  
AA1 3 4 N HIS A 60  ? N HIS A 60  O HIS A 76  ? O HIS A 76  
AA2 1 2 N SER A 38  ? N SER A 38  O PHE A 50  ? O PHE A 50  
AA2 2 3 N VAL A 52  ? N VAL A 52  O ILE A 365 ? O ILE A 365 
AA3 1 2 N ALA A 87  ? N ALA A 87  O PHE A 99  ? O PHE A 99  
AA3 2 3 N VAL A 100 ? N VAL A 100 O TRP A 108 ? O TRP A 108 
AA3 3 4 N VAL A 114 ? N VAL A 114 O ALA A 117 ? O ALA A 117 
AA4 1 2 N ALA A 87  ? N ALA A 87  O PHE A 99  ? O PHE A 99  
AA4 2 3 N VAL A 100 ? N VAL A 100 O TRP A 108 ? O TRP A 108 
AA4 3 4 N LEU A 107 ? N LEU A 107 O LEU A 125 ? O LEU A 125 
AA5 1 2 N TYR A 136 ? N TYR A 136 O GLU A 144 ? O GLU A 144 
AA5 2 3 N VAL A 145 ? N VAL A 145 O ILE A 157 ? O ILE A 157 
AA5 3 4 N THR A 160 ? N THR A 160 O PRO A 166 ? O PRO A 166 
AA6 1 2 N TYR A 136 ? N TYR A 136 O GLU A 144 ? O GLU A 144 
AA6 2 3 N VAL A 145 ? N VAL A 145 O ILE A 157 ? O ILE A 157 
AA6 3 4 N HIS A 156 ? N HIS A 156 O GLN A 171 ? O GLN A 171 
AA7 1 2 N THR A 182 ? N THR A 182 O PHE A 194 ? O PHE A 194 
AA7 2 3 N VAL A 193 ? N VAL A 193 O ILE A 205 ? O ILE A 205 
AA7 3 4 N TYR A 204 ? N TYR A 204 O GLN A 219 ? O GLN A 219 
AA8 1 2 N VAL A 230 ? N VAL A 230 O PHE A 242 ? O PHE A 242 
AA8 2 3 N ALA A 243 ? N ALA A 243 O TRP A 251 ? O TRP A 251 
AA8 3 4 N HIS A 252 ? N HIS A 252 O ARG A 266 ? O ARG A 266 
AA9 1 2 N ALA A 277 ? N ALA A 277 O PHE A 289 ? O PHE A 289 
AA9 2 3 N ALA A 290 ? N ALA A 290 O TRP A 298 ? O TRP A 298 
AA9 3 4 N HIS A 299 ? N HIS A 299 O THR A 313 ? O THR A 313 
AB1 1 2 N ALA A 326 ? N ALA A 326 O GLU A 334 ? O GLU A 334 
AB1 2 3 N ALA A 337 ? N ALA A 337 O CYS A 345 ? O CYS A 345 
AB1 3 4 N HIS A 346 ? N HIS A 346 O THR A 358 ? O THR A 358 
# 
_pdbx_entry_details.entry_id                   8Q81 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 67  ? ? 76.94   -4.82   
2  1 SER A 70  ? ? -140.08 -6.89   
3  1 ASN A 79  ? ? 63.85   176.79  
4  1 GLU A 80  ? ? 68.77   -155.49 
5  1 ASN A 174 ? ? 61.28   -151.91 
6  1 SER A 222 ? ? 60.06   -153.20 
7  1 SER A 269 ? ? 60.60   -156.92 
8  1 SER A 269 ? ? 56.04   -154.33 
9  1 SER A 316 ? A 62.63   -148.11 
10 1 SER A 316 ? B 55.92   -152.47 
11 1 SER A 353 ? ? -161.15 -157.37 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     238 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.088 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1  ? A MET 1  
2  1 Y 1 A LYS 2  ? A LYS 2  
3  1 Y 1 A LYS 3  ? A LYS 3  
4  1 Y 1 A GLU 4  ? A GLU 4  
5  1 Y 1 A SER 5  ? A SER 5  
6  1 Y 1 A ILE 6  ? A ILE 6  
7  1 Y 1 A ASN 7  ? A ASN 7  
8  1 Y 1 A THR 8  ? A THR 8  
9  1 Y 1 A SER 9  ? A SER 9  
10 1 Y 1 A GLY 10 ? A GLY 10 
11 1 Y 1 A PRO 11 ? A PRO 11 
12 1 Y 1 A ASP 12 ? A ASP 12 
13 1 Y 1 A ASN 13 ? A ASN 13 
14 1 Y 1 A THR 14 ? A THR 14 
15 1 Y 1 A LYS 15 ? A LYS 15 
16 1 Y 1 A SER 16 ? A SER 16 
17 1 Y 1 A SER 17 ? A SER 17 
18 1 Y 1 A ILE 18 ? A ILE 18 
19 1 Y 1 A SER 19 ? A SER 19 
20 1 Y 1 A ASP 20 ? A ASP 20 
21 1 Y 1 A GLU 21 ? A GLU 21 
22 1 Y 1 A ILE 22 ? A ILE 22 
23 1 Y 1 A GLU 23 ? A GLU 23 
24 1 Y 1 A ILE 24 ? A ILE 24 
25 1 Y 1 A SER 25 ? A SER 25 
26 1 Y 1 A ASN 26 ? A ASN 26 
27 1 Y 1 A GLU 27 ? A GLU 27 
28 1 Y 1 A ILE 28 ? A ILE 28 
29 1 Y 1 A SER 29 ? A SER 29 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
HIS N    N N N 147 
HIS CA   C N S 148 
HIS C    C N N 149 
HIS O    O N N 150 
HIS CB   C N N 151 
HIS CG   C Y N 152 
HIS ND1  N Y N 153 
HIS CD2  C Y N 154 
HIS CE1  C Y N 155 
HIS NE2  N Y N 156 
HIS OXT  O N N 157 
HIS H    H N N 158 
HIS H2   H N N 159 
HIS HA   H N N 160 
HIS HB2  H N N 161 
HIS HB3  H N N 162 
HIS HD1  H N N 163 
HIS HD2  H N N 164 
HIS HE1  H N N 165 
HIS HE2  H N N 166 
HIS HXT  H N N 167 
HOH O    O N N 168 
HOH H1   H N N 169 
HOH H2   H N N 170 
ILE N    N N N 171 
ILE CA   C N S 172 
ILE C    C N N 173 
ILE O    O N N 174 
ILE CB   C N S 175 
ILE CG1  C N N 176 
ILE CG2  C N N 177 
ILE CD1  C N N 178 
ILE OXT  O N N 179 
ILE H    H N N 180 
ILE H2   H N N 181 
ILE HA   H N N 182 
ILE HB   H N N 183 
ILE HG12 H N N 184 
ILE HG13 H N N 185 
ILE HG21 H N N 186 
ILE HG22 H N N 187 
ILE HG23 H N N 188 
ILE HD11 H N N 189 
ILE HD12 H N N 190 
ILE HD13 H N N 191 
ILE HXT  H N N 192 
LEU N    N N N 193 
LEU CA   C N S 194 
LEU C    C N N 195 
LEU O    O N N 196 
LEU CB   C N N 197 
LEU CG   C N N 198 
LEU CD1  C N N 199 
LEU CD2  C N N 200 
LEU OXT  O N N 201 
LEU H    H N N 202 
LEU H2   H N N 203 
LEU HA   H N N 204 
LEU HB2  H N N 205 
LEU HB3  H N N 206 
LEU HG   H N N 207 
LEU HD11 H N N 208 
LEU HD12 H N N 209 
LEU HD13 H N N 210 
LEU HD21 H N N 211 
LEU HD22 H N N 212 
LEU HD23 H N N 213 
LEU HXT  H N N 214 
LYS N    N N N 215 
LYS CA   C N S 216 
LYS C    C N N 217 
LYS O    O N N 218 
LYS CB   C N N 219 
LYS CG   C N N 220 
LYS CD   C N N 221 
LYS CE   C N N 222 
LYS NZ   N N N 223 
LYS OXT  O N N 224 
LYS H    H N N 225 
LYS H2   H N N 226 
LYS HA   H N N 227 
LYS HB2  H N N 228 
LYS HB3  H N N 229 
LYS HG2  H N N 230 
LYS HG3  H N N 231 
LYS HD2  H N N 232 
LYS HD3  H N N 233 
LYS HE2  H N N 234 
LYS HE3  H N N 235 
LYS HZ1  H N N 236 
LYS HZ2  H N N 237 
LYS HZ3  H N N 238 
LYS HXT  H N N 239 
MET N    N N N 240 
MET CA   C N S 241 
MET C    C N N 242 
MET O    O N N 243 
MET CB   C N N 244 
MET CG   C N N 245 
MET SD   S N N 246 
MET CE   C N N 247 
MET OXT  O N N 248 
MET H    H N N 249 
MET H2   H N N 250 
MET HA   H N N 251 
MET HB2  H N N 252 
MET HB3  H N N 253 
MET HG2  H N N 254 
MET HG3  H N N 255 
MET HE1  H N N 256 
MET HE2  H N N 257 
MET HE3  H N N 258 
MET HXT  H N N 259 
MFU C1   C N R 260 
MFU C2   C N S 261 
MFU C3   C N R 262 
MFU C4   C N S 263 
MFU C5   C N S 264 
MFU C6   C N N 265 
MFU O1   O N N 266 
MFU O2   O N N 267 
MFU O3   O N N 268 
MFU O4   O N N 269 
MFU O5   O N N 270 
MFU CM   C N N 271 
MFU H1   H N N 272 
MFU H2   H N N 273 
MFU H3   H N N 274 
MFU H4   H N N 275 
MFU H5   H N N 276 
MFU H61  H N N 277 
MFU H62  H N N 278 
MFU H63  H N N 279 
MFU HO2  H N N 280 
MFU HO3  H N N 281 
MFU HO4  H N N 282 
MFU HM1  H N N 283 
MFU HM2  H N N 284 
MFU HM3  H N N 285 
PEG C1   C N N 286 
PEG O1   O N N 287 
PEG C2   C N N 288 
PEG O2   O N N 289 
PEG C3   C N N 290 
PEG C4   C N N 291 
PEG O4   O N N 292 
PEG H11  H N N 293 
PEG H12  H N N 294 
PEG HO1  H N N 295 
PEG H21  H N N 296 
PEG H22  H N N 297 
PEG H31  H N N 298 
PEG H32  H N N 299 
PEG H41  H N N 300 
PEG H42  H N N 301 
PEG HO4  H N N 302 
PHE N    N N N 303 
PHE CA   C N S 304 
PHE C    C N N 305 
PHE O    O N N 306 
PHE CB   C N N 307 
PHE CG   C Y N 308 
PHE CD1  C Y N 309 
PHE CD2  C Y N 310 
PHE CE1  C Y N 311 
PHE CE2  C Y N 312 
PHE CZ   C Y N 313 
PHE OXT  O N N 314 
PHE H    H N N 315 
PHE H2   H N N 316 
PHE HA   H N N 317 
PHE HB2  H N N 318 
PHE HB3  H N N 319 
PHE HD1  H N N 320 
PHE HD2  H N N 321 
PHE HE1  H N N 322 
PHE HE2  H N N 323 
PHE HZ   H N N 324 
PHE HXT  H N N 325 
PRO N    N N N 326 
PRO CA   C N S 327 
PRO C    C N N 328 
PRO O    O N N 329 
PRO CB   C N N 330 
PRO CG   C N N 331 
PRO CD   C N N 332 
PRO OXT  O N N 333 
PRO H    H N N 334 
PRO HA   H N N 335 
PRO HB2  H N N 336 
PRO HB3  H N N 337 
PRO HG2  H N N 338 
PRO HG3  H N N 339 
PRO HD2  H N N 340 
PRO HD3  H N N 341 
PRO HXT  H N N 342 
SER N    N N N 343 
SER CA   C N S 344 
SER C    C N N 345 
SER O    O N N 346 
SER CB   C N N 347 
SER OG   O N N 348 
SER OXT  O N N 349 
SER H    H N N 350 
SER H2   H N N 351 
SER HA   H N N 352 
SER HB2  H N N 353 
SER HB3  H N N 354 
SER HG   H N N 355 
SER HXT  H N N 356 
THR N    N N N 357 
THR CA   C N S 358 
THR C    C N N 359 
THR O    O N N 360 
THR CB   C N R 361 
THR OG1  O N N 362 
THR CG2  C N N 363 
THR OXT  O N N 364 
THR H    H N N 365 
THR H2   H N N 366 
THR HA   H N N 367 
THR HB   H N N 368 
THR HG1  H N N 369 
THR HG21 H N N 370 
THR HG22 H N N 371 
THR HG23 H N N 372 
THR HXT  H N N 373 
TRP N    N N N 374 
TRP CA   C N S 375 
TRP C    C N N 376 
TRP O    O N N 377 
TRP CB   C N N 378 
TRP CG   C Y N 379 
TRP CD1  C Y N 380 
TRP CD2  C Y N 381 
TRP NE1  N Y N 382 
TRP CE2  C Y N 383 
TRP CE3  C Y N 384 
TRP CZ2  C Y N 385 
TRP CZ3  C Y N 386 
TRP CH2  C Y N 387 
TRP OXT  O N N 388 
TRP H    H N N 389 
TRP H2   H N N 390 
TRP HA   H N N 391 
TRP HB2  H N N 392 
TRP HB3  H N N 393 
TRP HD1  H N N 394 
TRP HE1  H N N 395 
TRP HE3  H N N 396 
TRP HZ2  H N N 397 
TRP HZ3  H N N 398 
TRP HH2  H N N 399 
TRP HXT  H N N 400 
TYR N    N N N 401 
TYR CA   C N S 402 
TYR C    C N N 403 
TYR O    O N N 404 
TYR CB   C N N 405 
TYR CG   C Y N 406 
TYR CD1  C Y N 407 
TYR CD2  C Y N 408 
TYR CE1  C Y N 409 
TYR CE2  C Y N 410 
TYR CZ   C Y N 411 
TYR OH   O N N 412 
TYR OXT  O N N 413 
TYR H    H N N 414 
TYR H2   H N N 415 
TYR HA   H N N 416 
TYR HB2  H N N 417 
TYR HB3  H N N 418 
TYR HD1  H N N 419 
TYR HD2  H N N 420 
TYR HE1  H N N 421 
TYR HE2  H N N 422 
TYR HH   H N N 423 
TYR HXT  H N N 424 
VAL N    N N N 425 
VAL CA   C N S 426 
VAL C    C N N 427 
VAL O    O N N 428 
VAL CB   C N N 429 
VAL CG1  C N N 430 
VAL CG2  C N N 431 
VAL OXT  O N N 432 
VAL H    H N N 433 
VAL H2   H N N 434 
VAL HA   H N N 435 
VAL HB   H N N 436 
VAL HG11 H N N 437 
VAL HG12 H N N 438 
VAL HG13 H N N 439 
VAL HG21 H N N 440 
VAL HG22 H N N 441 
VAL HG23 H N N 442 
VAL HXT  H N N 443 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
MFU C1  C2   sing N N 246 
MFU C1  O1   sing N N 247 
MFU C1  O5   sing N N 248 
MFU C1  H1   sing N N 249 
MFU C2  C3   sing N N 250 
MFU C2  O2   sing N N 251 
MFU C2  H2   sing N N 252 
MFU C3  C4   sing N N 253 
MFU C3  O3   sing N N 254 
MFU C3  H3   sing N N 255 
MFU C4  C5   sing N N 256 
MFU C4  O4   sing N N 257 
MFU C4  H4   sing N N 258 
MFU C5  C6   sing N N 259 
MFU C5  O5   sing N N 260 
MFU C5  H5   sing N N 261 
MFU C6  H61  sing N N 262 
MFU C6  H62  sing N N 263 
MFU C6  H63  sing N N 264 
MFU O1  CM   sing N N 265 
MFU O2  HO2  sing N N 266 
MFU O3  HO3  sing N N 267 
MFU O4  HO4  sing N N 268 
MFU CM  HM1  sing N N 269 
MFU CM  HM2  sing N N 270 
MFU CM  HM3  sing N N 271 
PEG C1  O1   sing N N 272 
PEG C1  C2   sing N N 273 
PEG C1  H11  sing N N 274 
PEG C1  H12  sing N N 275 
PEG O1  HO1  sing N N 276 
PEG C2  O2   sing N N 277 
PEG C2  H21  sing N N 278 
PEG C2  H22  sing N N 279 
PEG O2  C3   sing N N 280 
PEG C3  C4   sing N N 281 
PEG C3  H31  sing N N 282 
PEG C3  H32  sing N N 283 
PEG C4  O4   sing N N 284 
PEG C4  H41  sing N N 285 
PEG C4  H42  sing N N 286 
PEG O4  HO4  sing N N 287 
PHE N   CA   sing N N 288 
PHE N   H    sing N N 289 
PHE N   H2   sing N N 290 
PHE CA  C    sing N N 291 
PHE CA  CB   sing N N 292 
PHE CA  HA   sing N N 293 
PHE C   O    doub N N 294 
PHE C   OXT  sing N N 295 
PHE CB  CG   sing N N 296 
PHE CB  HB2  sing N N 297 
PHE CB  HB3  sing N N 298 
PHE CG  CD1  doub Y N 299 
PHE CG  CD2  sing Y N 300 
PHE CD1 CE1  sing Y N 301 
PHE CD1 HD1  sing N N 302 
PHE CD2 CE2  doub Y N 303 
PHE CD2 HD2  sing N N 304 
PHE CE1 CZ   doub Y N 305 
PHE CE1 HE1  sing N N 306 
PHE CE2 CZ   sing Y N 307 
PHE CE2 HE2  sing N N 308 
PHE CZ  HZ   sing N N 309 
PHE OXT HXT  sing N N 310 
PRO N   CA   sing N N 311 
PRO N   CD   sing N N 312 
PRO N   H    sing N N 313 
PRO CA  C    sing N N 314 
PRO CA  CB   sing N N 315 
PRO CA  HA   sing N N 316 
PRO C   O    doub N N 317 
PRO C   OXT  sing N N 318 
PRO CB  CG   sing N N 319 
PRO CB  HB2  sing N N 320 
PRO CB  HB3  sing N N 321 
PRO CG  CD   sing N N 322 
PRO CG  HG2  sing N N 323 
PRO CG  HG3  sing N N 324 
PRO CD  HD2  sing N N 325 
PRO CD  HD3  sing N N 326 
PRO OXT HXT  sing N N 327 
SER N   CA   sing N N 328 
SER N   H    sing N N 329 
SER N   H2   sing N N 330 
SER CA  C    sing N N 331 
SER CA  CB   sing N N 332 
SER CA  HA   sing N N 333 
SER C   O    doub N N 334 
SER C   OXT  sing N N 335 
SER CB  OG   sing N N 336 
SER CB  HB2  sing N N 337 
SER CB  HB3  sing N N 338 
SER OG  HG   sing N N 339 
SER OXT HXT  sing N N 340 
THR N   CA   sing N N 341 
THR N   H    sing N N 342 
THR N   H2   sing N N 343 
THR CA  C    sing N N 344 
THR CA  CB   sing N N 345 
THR CA  HA   sing N N 346 
THR C   O    doub N N 347 
THR C   OXT  sing N N 348 
THR CB  OG1  sing N N 349 
THR CB  CG2  sing N N 350 
THR CB  HB   sing N N 351 
THR OG1 HG1  sing N N 352 
THR CG2 HG21 sing N N 353 
THR CG2 HG22 sing N N 354 
THR CG2 HG23 sing N N 355 
THR OXT HXT  sing N N 356 
TRP N   CA   sing N N 357 
TRP N   H    sing N N 358 
TRP N   H2   sing N N 359 
TRP CA  C    sing N N 360 
TRP CA  CB   sing N N 361 
TRP CA  HA   sing N N 362 
TRP C   O    doub N N 363 
TRP C   OXT  sing N N 364 
TRP CB  CG   sing N N 365 
TRP CB  HB2  sing N N 366 
TRP CB  HB3  sing N N 367 
TRP CG  CD1  doub Y N 368 
TRP CG  CD2  sing Y N 369 
TRP CD1 NE1  sing Y N 370 
TRP CD1 HD1  sing N N 371 
TRP CD2 CE2  doub Y N 372 
TRP CD2 CE3  sing Y N 373 
TRP NE1 CE2  sing Y N 374 
TRP NE1 HE1  sing N N 375 
TRP CE2 CZ2  sing Y N 376 
TRP CE3 CZ3  doub Y N 377 
TRP CE3 HE3  sing N N 378 
TRP CZ2 CH2  doub Y N 379 
TRP CZ2 HZ2  sing N N 380 
TRP CZ3 CH2  sing Y N 381 
TRP CZ3 HZ3  sing N N 382 
TRP CH2 HH2  sing N N 383 
TRP OXT HXT  sing N N 384 
TYR N   CA   sing N N 385 
TYR N   H    sing N N 386 
TYR N   H2   sing N N 387 
TYR CA  C    sing N N 388 
TYR CA  CB   sing N N 389 
TYR CA  HA   sing N N 390 
TYR C   O    doub N N 391 
TYR C   OXT  sing N N 392 
TYR CB  CG   sing N N 393 
TYR CB  HB2  sing N N 394 
TYR CB  HB3  sing N N 395 
TYR CG  CD1  doub Y N 396 
TYR CG  CD2  sing Y N 397 
TYR CD1 CE1  sing Y N 398 
TYR CD1 HD1  sing N N 399 
TYR CD2 CE2  doub Y N 400 
TYR CD2 HD2  sing N N 401 
TYR CE1 CZ   doub Y N 402 
TYR CE1 HE1  sing N N 403 
TYR CE2 CZ   sing Y N 404 
TYR CE2 HE2  sing N N 405 
TYR CZ  OH   sing N N 406 
TYR OH  HH   sing N N 407 
TYR OXT HXT  sing N N 408 
VAL N   CA   sing N N 409 
VAL N   H    sing N N 410 
VAL N   H2   sing N N 411 
VAL CA  C    sing N N 412 
VAL CA  CB   sing N N 413 
VAL CA  HA   sing N N 414 
VAL C   O    doub N N 415 
VAL C   OXT  sing N N 416 
VAL CB  CG1  sing N N 417 
VAL CB  CG2  sing N N 418 
VAL CB  HB   sing N N 419 
VAL CG1 HG11 sing N N 420 
VAL CG1 HG12 sing N N 421 
VAL CG1 HG13 sing N N 422 
VAL CG2 HG21 sing N N 423 
VAL CG2 HG22 sing N N 424 
VAL CG2 HG23 sing N N 425 
VAL OXT HXT  sing N N 426 
# 
_pdbx_audit_support.funding_organization   'Grant Agency of the Czech Republic' 
_pdbx_audit_support.country                'Czech Republic' 
_pdbx_audit_support.grant_number           21-29622S 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6T96 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8Q81 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017664 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014364 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013116 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0487   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . TRP A 1 30  ? 10.426  7.881   -27.352 1.000 33.394 0 30  TRP A N   1 ? 
ATOM   2    C CA  . TRP A 1 30  ? 10.974  8.819   -26.329 1.000 34.807 0 30  TRP A CA  1 ? 
ATOM   3    C C   . TRP A 1 30  ? 11.334  8.065   -25.054 1.000 32.705 0 30  TRP A C   1 ? 
ATOM   4    O O   . TRP A 1 30  ? 10.871  8.409   -23.984 1.000 28.619 0 30  TRP A O   1 ? 
ATOM   5    C CB  . TRP A 1 30  ? 9.984   9.958   -26.053 1.000 33.867 0 30  TRP A CB  1 ? 
ATOM   6    C CG  . TRP A 1 30  ? 9.862   10.895  -27.224 1.000 32.137 0 30  TRP A CG  1 ? 
ATOM   7    C CD1 . TRP A 1 30  ? 8.748   11.191  -27.956 1.000 32.461 0 30  TRP A CD1 1 ? 
ATOM   8    C CD2 . TRP A 1 30  ? 10.955  11.632  -27.826 1.000 33.232 0 30  TRP A CD2 1 ? 
ATOM   9    N NE1 . TRP A 1 30  ? 9.053   12.102  -28.932 1.000 29.785 0 30  TRP A NE1 1 ? 
ATOM   10   C CE2 . TRP A 1 30  ? 10.399  12.386  -28.887 1.000 30.856 0 30  TRP A CE2 1 ? 
ATOM   11   C CE3 . TRP A 1 30  ? 12.337  11.729  -27.570 1.000 37.404 0 30  TRP A CE3 1 ? 
ATOM   12   C CZ2 . TRP A 1 30  ? 11.188  13.214  -29.689 1.000 32.322 0 30  TRP A CZ2 1 ? 
ATOM   13   C CZ3 . TRP A 1 30  ? 13.115  12.538  -28.374 1.000 33.627 0 30  TRP A CZ3 1 ? 
ATOM   14   C CH2 . TRP A 1 30  ? 12.547  13.250  -29.431 1.000 33.618 0 30  TRP A CH2 1 ? 
ATOM   15   N N   . THR A 1 31  ? 12.197  7.054   -25.197 1.000 35.694 0 31  THR A N   1 ? 
ATOM   16   C CA  . THR A 1 31  ? 12.625  6.190   -24.108 1.000 34.938 0 31  THR A CA  1 ? 
ATOM   17   C C   . THR A 1 31  ? 14.123  6.411   -23.934 1.000 33.756 0 31  THR A C   1 ? 
ATOM   18   O O   . THR A 1 31  ? 14.788  6.793   -24.898 1.000 39.238 0 31  THR A O   1 ? 
ATOM   19   C CB  . THR A 1 31  ? 12.356  4.712   -24.424 1.000 41.050 0 31  THR A CB  1 ? 
ATOM   20   O OG1 . THR A 1 31  ? 13.154  4.406   -25.573 1.000 42.480 0 31  THR A OG1 1 ? 
ATOM   21   C CG2 . THR A 1 31  ? 10.902  4.392   -24.700 1.000 44.218 0 31  THR A CG2 1 ? 
ATOM   22   N N   . ALA A 1 32  ? 14.621  6.219   -22.703 1.000 25.575 0 32  ALA A N   1 ? 
ATOM   23   C CA  . ALA A 1 32  ? 16.036  6.378   -22.396 1.000 24.062 0 32  ALA A CA  1 ? 
ATOM   24   C C   . ALA A 1 32  ? 16.585  4.996   -22.038 1.000 19.670 0 32  ALA A C   1 ? 
ATOM   25   O O   . ALA A 1 32  ? 15.838  4.072   -21.719 1.000 22.954 0 32  ALA A O   1 ? 
ATOM   26   C CB  . ALA A 1 32  ? 16.257  7.393   -21.276 1.000 23.967 0 32  ALA A CB  1 ? 
ATOM   27   N N   . LEU A 1 33  ? 17.893  4.870   -22.056 1.000 20.386 0 33  LEU A N   1 ? 
ATOM   28   C CA  . LEU A 1 33  ? 18.517  3.603   -21.736 1.000 17.441 0 33  LEU A CA  1 ? 
ATOM   29   C C   . LEU A 1 33  ? 18.244  3.221   -20.267 1.000 15.059 0 33  LEU A C   1 ? 
ATOM   30   O O   . LEU A 1 33  ? 18.362  4.013   -19.351 1.000 15.674 0 33  LEU A O   1 ? 
ATOM   31   C CB  . LEU A 1 33  ? 19.987  3.765   -22.087 1.000 22.779 0 33  LEU A CB  1 ? 
ATOM   32   C CG  . LEU A 1 33  ? 20.878  2.561   -21.876 1.000 22.903 0 33  LEU A CG  1 ? 
ATOM   33   C CD1 . LEU A 1 33  ? 20.432  1.398   -22.762 1.000 24.007 0 33  LEU A CD1 1 ? 
ATOM   34   C CD2 . LEU A 1 33  ? 22.331  2.982   -22.228 1.000 22.833 0 33  LEU A CD2 1 ? 
ATOM   35   N N   . SER A 1 34  ? 17.725  1.995   -20.095 1.000 16.308 0 34  SER A N   1 ? 
ATOM   36   C CA  . SER A 1 34  ? 17.393  1.403   -18.820 1.000 17.120 0 34  SER A CA  1 ? 
ATOM   37   C C   . SER A 1 34  ? 18.647  0.951   -18.068 1.000 14.452 0 34  SER A C   1 ? 
ATOM   38   O O   . SER A 1 34  ? 19.698  0.746   -18.670 1.000 13.381 0 34  SER A O   1 ? 
ATOM   39   C CB  . SER A 1 34  ? 16.491  0.160   -19.003 1.000 23.694 0 34  SER A CB  1 ? 
ATOM   40   O OG  . SER A 1 34  ? 15.341  0.519   -19.781 1.000 34.651 0 34  SER A OG  1 ? 
ATOM   41   N N   . GLY A 1 35  ? 18.486  0.732   -16.758 1.000 14.300 0 35  GLY A N   1 ? 
ATOM   42   C CA  . GLY A 1 35  ? 19.427  -0.111  -16.017 1.000 13.696 0 35  GLY A CA  1 ? 
ATOM   43   C C   . GLY A 1 35  ? 19.374  -1.560  -16.494 1.000 13.510 0 35  GLY A C   1 ? 
ATOM   44   O O   . GLY A 1 35  ? 18.377  -1.968  -17.089 1.000 14.107 0 35  GLY A O   1 ? 
ATOM   45   N N   . VAL A 1 36  ? 20.445  -2.325  -16.238 1.000 12.942 0 36  VAL A N   1 ? 
ATOM   46   C CA  . VAL A 1 36  ? 20.507  -3.718  -16.674 1.000 12.800 0 36  VAL A CA  1 ? 
ATOM   47   C C   . VAL A 1 36  ? 20.556  -4.686  -15.507 1.000 12.172 0 36  VAL A C   1 ? 
ATOM   48   O O   . VAL A 1 36  ? 20.662  -5.882  -15.745 1.000 12.414 0 36  VAL A O   1 ? 
ATOM   49   C CB  . VAL A 1 36  ? 21.666  -3.955  -17.643 1.000 14.430 0 36  VAL A CB  1 ? 
ATOM   50   C CG1 . VAL A 1 36  ? 21.390  -3.281  -18.984 1.000 16.131 0 36  VAL A CG1 1 ? 
ATOM   51   C CG2 . VAL A 1 36  ? 22.971  -3.531  -17.012 1.000 15.442 0 36  VAL A CG2 1 ? 
ATOM   52   N N   . ILE A 1 37  ? 20.550  -4.199  -14.253 1.000 11.379 0 37  ILE A N   1 ? 
ATOM   53   C CA  . ILE A 1 37  ? 20.395  -5.093  -13.108 1.000 11.356 0 37  ILE A CA  1 ? 
ATOM   54   C C   . ILE A 1 37  ? 19.369  -4.503  -12.145 1.000 12.669 0 37  ILE A C   1 ? 
ATOM   55   O O   . ILE A 1 37  ? 18.999  -3.335  -12.221 1.000 13.707 0 37  ILE A O   1 ? 
ATOM   56   C CB  . ILE A 1 37  ? 21.707  -5.331  -12.350 1.000 12.430 0 37  ILE A CB  1 ? 
ATOM   57   C CG1 . ILE A 1 37  ? 22.296  -4.011  -11.839 1.000 12.467 0 37  ILE A CG1 1 ? 
ATOM   58   C CG2 . ILE A 1 37  ? 22.692  -6.114  -13.216 1.000 13.738 0 37  ILE A CG2 1 ? 
ATOM   59   C CD1 . ILE A 1 37  ? 23.035  -4.132  -10.547 1.000 14.877 0 37  ILE A CD1 1 ? 
ATOM   60   N N   A SER A 1 38  ? 18.981  -5.353  -11.200 0.700 11.212 0 38  SER A N   1 ? 
ATOM   61   N N   B SER A 1 38  ? 18.887  -5.350  -11.248 0.300 12.059 0 38  SER A N   1 ? 
ATOM   62   C CA  A SER A 1 38  ? 18.256  -5.026  -9.990  0.700 10.118 0 38  SER A CA  1 ? 
ATOM   63   C CA  B SER A 1 38  ? 18.346  -4.869  -9.998  0.300 11.670 0 38  SER A CA  1 ? 
ATOM   64   C C   A SER A 1 38  ? 19.086  -5.524  -8.818  0.700 10.971 0 38  SER A C   1 ? 
ATOM   65   C C   B SER A 1 38  ? 19.193  -5.430  -8.873  0.300 11.622 0 38  SER A C   1 ? 
ATOM   66   O O   A SER A 1 38  ? 19.575  -6.656  -8.852  0.700 11.274 0 38  SER A O   1 ? 
ATOM   67   O O   B SER A 1 38  ? 19.881  -6.434  -9.028  0.300 11.735 0 38  SER A O   1 ? 
ATOM   68   C CB  A SER A 1 38  ? 16.900  -5.694  -10.018 0.700 11.080 0 38  SER A CB  1 ? 
ATOM   69   C CB  B SER A 1 38  ? 16.895  -5.189  -9.862  0.300 12.419 0 38  SER A CB  1 ? 
ATOM   70   O OG  A SER A 1 38  ? 16.127  -5.279  -8.921  0.700 10.927 0 38  SER A OG  1 ? 
ATOM   71   O OG  B SER A 1 38  ? 16.198  -4.675  -10.981 0.300 13.037 0 38  SER A OG  1 ? 
ATOM   72   N N   . ALA A 1 39  ? 19.188  -4.700  -7.766  1.000 11.089 0 39  ALA A N   1 ? 
ATOM   73   C CA  . ALA A 1 39  ? 20.033  -5.027  -6.622  1.000 11.665 0 39  ALA A CA  1 ? 
ATOM   74   C C   . ALA A 1 39  ? 19.181  -5.001  -5.384  1.000 12.501 0 39  ALA A C   1 ? 
ATOM   75   O O   . ALA A 1 39  ? 18.250  -4.215  -5.275  1.000 14.252 0 39  ALA A O   1 ? 
ATOM   76   C CB  . ALA A 1 39  ? 21.132  -4.003  -6.486  1.000 13.560 0 39  ALA A CB  1 ? 
ATOM   77   N N   . ALA A 1 40  ? 19.609  -5.812  -4.416  1.000 11.998 0 40  ALA A N   1 ? 
ATOM   78   C CA  . ALA A 1 40  ? 19.025  -5.770  -3.084  1.000 12.768 0 40  ALA A CA  1 ? 
ATOM   79   C C   . ALA A 1 40  ? 20.077  -6.177  -2.075  1.000 12.337 0 40  ALA A C   1 ? 
ATOM   80   O O   . ALA A 1 40  ? 20.965  -6.947  -2.406  1.000 13.590 0 40  ALA A O   1 ? 
ATOM   81   C CB  . ALA A 1 40  ? 17.834  -6.678  -2.953  1.000 14.432 0 40  ALA A CB  1 ? 
ATOM   82   N N   . ASN A 1 41  ? 19.845  -5.769  -0.813  1.000 12.970 0 41  ASN A N   1 ? 
ATOM   83   C CA  . ASN A 1 41  ? 20.564  -6.370  0.291   1.000 12.528 0 41  ASN A CA  1 ? 
ATOM   84   C C   . ASN A 1 41  ? 19.845  -7.627  0.780   1.000 12.449 0 41  ASN A C   1 ? 
ATOM   85   O O   . ASN A 1 41  ? 18.649  -7.606  1.008   1.000 12.733 0 41  ASN A O   1 ? 
ATOM   86   C CB  . ASN A 1 41  ? 20.714  -5.428  1.491   1.000 13.207 0 41  ASN A CB  1 ? 
ATOM   87   C CG  . ASN A 1 41  ? 21.356  -4.116  1.120   1.000 13.778 0 41  ASN A CG  1 ? 
ATOM   88   O OD1 . ASN A 1 41  ? 20.665  -3.252  0.611   1.000 15.546 0 41  ASN A OD1 1 ? 
ATOM   89   N ND2 . ASN A 1 41  ? 22.655  -3.983  1.328   1.000 14.907 0 41  ASN A ND2 1 ? 
ATOM   90   N N   . ASN A 1 42  ? 20.626  -8.681  1.018   1.000 11.767 0 42  ASN A N   1 ? 
ATOM   91   C CA  . ASN A 1 42  ? 20.195  -9.821  1.811   1.000 11.997 0 42  ASN A CA  1 ? 
ATOM   92   C C   . ASN A 1 42  ? 19.930  -9.358  3.246   1.000 12.935 0 42  ASN A C   1 ? 
ATOM   93   O O   . ASN A 1 42  ? 20.307  -8.272  3.643   1.000 14.423 0 42  ASN A O   1 ? 
ATOM   94   C CB  . ASN A 1 42  ? 21.221  -10.963 1.741   1.000 12.589 0 42  ASN A CB  1 ? 
ATOM   95   C CG  . ASN A 1 42  ? 21.123  -11.766 0.467   1.000 11.520 0 42  ASN A CG  1 ? 
ATOM   96   O OD1 . ASN A 1 42  ? 20.335  -12.708 0.376   1.000 11.845 0 42  ASN A OD1 1 ? 
ATOM   97   N ND2 . ASN A 1 42  ? 21.924  -11.398 -0.518  1.000 11.993 0 42  ASN A ND2 1 ? 
ATOM   98   N N   . ALA A 1 43  ? 19.275  -10.216 3.995   1.000 14.281 0 43  ALA A N   1 ? 
ATOM   99   C CA  . ALA A 1 43  ? 18.924  -9.931  5.371   1.000 15.425 0 43  ALA A CA  1 ? 
ATOM   100  C C   . ALA A 1 43  ? 20.171  -9.578  6.175   1.000 16.045 0 43  ALA A C   1 ? 
ATOM   101  O O   . ALA A 1 43  ? 20.118  -8.739  7.088   1.000 18.742 0 43  ALA A O   1 ? 
ATOM   102  C CB  . ALA A 1 43  ? 18.170  -11.109 5.938   1.000 16.025 0 43  ALA A CB  1 ? 
ATOM   103  N N   . ASP A 1 44  ? 21.281  -10.234 5.856   1.000 13.972 0 44  ASP A N   1 ? 
ATOM   104  C CA  . ASP A 1 44  ? 22.553  -10.025 6.552   1.000 15.794 0 44  ASP A CA  1 ? 
ATOM   105  C C   . ASP A 1 44  ? 23.351  -8.840  5.998   1.000 16.904 0 44  ASP A C   1 ? 
ATOM   106  O O   . ASP A 1 44  ? 24.455  -8.598  6.479   1.000 18.348 0 44  ASP A O   1 ? 
ATOM   107  C CB  . ASP A 1 44  ? 23.419  -11.292 6.504   1.000 16.375 0 44  ASP A CB  1 ? 
ATOM   108  C CG  . ASP A 1 44  ? 23.876  -11.716 5.124   1.000 16.779 0 44  ASP A CG  1 ? 
ATOM   109  O OD1 . ASP A 1 44  ? 23.594  -10.967 4.176   1.000 15.434 0 44  ASP A OD1 1 ? 
ATOM   110  O OD2 . ASP A 1 44  ? 24.563  -12.750 4.991   1.000 16.993 0 44  ASP A OD2 1 ? 
ATOM   111  N N   . GLY A 1 45  ? 22.813  -8.095  5.022   1.000 14.411 0 45  GLY A N   1 ? 
ATOM   112  C CA  . GLY A 1 45  ? 23.499  -6.923  4.483   1.000 14.535 0 45  GLY A CA  1 ? 
ATOM   113  C C   . GLY A 1 45  ? 24.161  -7.135  3.126   1.000 14.836 0 45  GLY A C   1 ? 
ATOM   114  O O   . GLY A 1 45  ? 24.461  -6.136  2.480   1.000 14.899 0 45  GLY A O   1 ? 
ATOM   115  N N   . ARG A 1 46  ? 24.470  -8.376  2.729   1.000 13.324 0 46  ARG A N   1 ? 
ATOM   116  C CA  . ARG A 1 46  ? 25.240  -8.594  1.504   1.000 12.823 0 46  ARG A CA  1 ? 
ATOM   117  C C   . ARG A 1 46  ? 24.415  -8.181  0.288   1.000 13.039 0 46  ARG A C   1 ? 
ATOM   118  O O   . ARG A 1 46  ? 23.306  -8.642  0.092   1.000 12.742 0 46  ARG A O   1 ? 
ATOM   119  C CB  . ARG A 1 46  ? 25.581  -10.081 1.365   1.000 13.121 0 46  ARG A CB  1 ? 
ATOM   120  C CG  . ARG A 1 46  ? 26.473  -10.613 2.484   1.000 13.837 0 46  ARG A CG  1 ? 
ATOM   121  C CD  . ARG A 1 46  ? 26.708  -12.097 2.320   1.000 13.620 0 46  ARG A CD  1 ? 
ATOM   122  N NE  . ARG A 1 46  ? 25.463  -12.881 2.330   1.000 13.218 0 46  ARG A NE  1 ? 
ATOM   123  C CZ  . ARG A 1 46  ? 24.770  -13.251 1.286   1.000 13.499 0 46  ARG A CZ  1 ? 
ATOM   124  N NH1 . ARG A 1 46  ? 25.264  -13.083 0.087   1.000 14.073 0 46  ARG A NH1 1 ? 
ATOM   125  N NH2 . ARG A 1 46  ? 23.585  -13.809 1.450   1.000 15.411 0 46  ARG A NH2 1 ? 
ATOM   126  N N   . LEU A 1 47  ? 24.998  -7.362  -0.561  1.000 12.151 0 47  LEU A N   1 ? 
ATOM   127  C CA  . LEU A 1 47  ? 24.348  -7.000  -1.808  1.000 12.071 0 47  LEU A CA  1 ? 
ATOM   128  C C   . LEU A 1 47  ? 24.345  -8.175  -2.754  1.000 12.107 0 47  LEU A C   1 ? 
ATOM   129  O O   . LEU A 1 47  ? 25.247  -9.021  -2.800  1.000 11.828 0 47  LEU A O   1 ? 
ATOM   130  C CB  . LEU A 1 47  ? 25.070  -5.802  -2.449  1.000 12.417 0 47  LEU A CB  1 ? 
ATOM   131  C CG  . LEU A 1 47  ? 24.874  -4.454  -1.776  1.000 13.506 0 47  LEU A CG  1 ? 
ATOM   132  C CD1 . LEU A 1 47  ? 25.834  -3.428  -2.378  1.000 13.521 0 47  LEU A CD1 1 ? 
ATOM   133  C CD2 . LEU A 1 47  ? 23.444  -4.008  -1.994  1.000 14.551 0 47  LEU A CD2 1 ? 
ATOM   134  N N   . GLU A 1 48  ? 23.273  -8.200  -3.559  1.000 10.769 0 48  GLU A N   1 ? 
ATOM   135  C CA  . GLU A 1 48  ? 23.096  -9.221  -4.586  1.000 11.333 0 48  GLU A CA  1 ? 
ATOM   136  C C   . GLU A 1 48  ? 22.452  -8.568  -5.797  1.000 11.208 0 48  GLU A C   1 ? 
ATOM   137  O O   . GLU A 1 48  ? 21.481  -7.790  -5.654  1.000 11.454 0 48  GLU A O   1 ? 
ATOM   138  C CB  . GLU A 1 48  ? 22.287  -10.397 -4.021  1.000 11.609 0 48  GLU A CB  1 ? 
ATOM   139  C CG  . GLU A 1 48  ? 22.130  -11.605 -4.951  1.000 12.358 0 48  GLU A CG  1 ? 
ATOM   140  C CD  . GLU A 1 48  ? 21.736  -12.901 -4.248  1.000 12.959 0 48  GLU A CD  1 ? 
ATOM   141  O OE1 . GLU A 1 48  ? 21.821  -12.952 -2.995  1.000 13.223 0 48  GLU A OE1 1 ? 
ATOM   142  O OE2 . GLU A 1 48  ? 21.351  -13.853 -4.911  1.000 13.690 0 48  GLU A OE2 1 ? 
ATOM   143  N N   . VAL A 1 49  ? 22.962  -8.916  -6.985  1.000 10.680 0 49  VAL A N   1 ? 
ATOM   144  C CA  . VAL A 1 49  ? 22.493  -8.309  -8.211  1.000 11.078 0 49  VAL A CA  1 ? 
ATOM   145  C C   . VAL A 1 49  ? 21.955  -9.362  -9.148  1.000 11.029 0 49  VAL A C   1 ? 
ATOM   146  O O   . VAL A 1 49  ? 22.419  -10.503 -9.185  1.000 11.478 0 49  VAL A O   1 ? 
ATOM   147  C CB  . VAL A 1 49  ? 23.588  -7.466  -8.894  1.000 10.877 0 49  VAL A CB  1 ? 
ATOM   148  C CG1 . VAL A 1 49  ? 24.063  -6.366  -7.949  1.000 11.652 0 49  VAL A CG1 1 ? 
ATOM   149  C CG2 . VAL A 1 49  ? 24.723  -8.315  -9.389  1.000 12.046 0 49  VAL A CG2 1 ? 
ATOM   150  N N   . PHE A 1 50  ? 20.960  -8.943  -9.926  1.000 11.238 0 50  PHE A N   1 ? 
ATOM   151  C CA  . PHE A 1 50  ? 20.246  -9.806  -10.856 1.000 11.297 0 50  PHE A CA  1 ? 
ATOM   152  C C   . PHE A 1 50  ? 20.214  -9.106  -12.205 1.000 12.052 0 50  PHE A C   1 ? 
ATOM   153  O O   . PHE A 1 50  ? 19.788  -7.959  -12.258 1.000 11.696 0 50  PHE A O   1 ? 
ATOM   154  C CB  . PHE A 1 50  ? 18.826  -10.107 -10.374 1.000 11.148 0 50  PHE A CB  1 ? 
ATOM   155  C CG  . PHE A 1 50  ? 18.769  -10.792 -9.034  1.000 11.311 0 50  PHE A CG  1 ? 
ATOM   156  C CD1 . PHE A 1 50  ? 19.010  -10.061 -7.885  1.000 11.127 0 50  PHE A CD1 1 ? 
ATOM   157  C CD2 . PHE A 1 50  ? 18.505  -12.151 -8.929  1.000 11.605 0 50  PHE A CD2 1 ? 
ATOM   158  C CE1 . PHE A 1 50  ? 19.030  -10.689 -6.659  1.000 11.710 0 50  PHE A CE1 1 ? 
ATOM   159  C CE2 . PHE A 1 50  ? 18.499  -12.771 -7.695  1.000 12.249 0 50  PHE A CE2 1 ? 
ATOM   160  C CZ  . PHE A 1 50  ? 18.758  -12.027 -6.561  1.000 11.926 0 50  PHE A CZ  1 ? 
ATOM   161  N N   . GLY A 1 51  ? 20.578  -9.828  -13.275 1.000 10.613 0 51  GLY A N   1 ? 
ATOM   162  C CA  . GLY A 1 51  ? 20.523  -9.286  -14.623 1.000 11.235 0 51  GLY A CA  1 ? 
ATOM   163  C C   . GLY A 1 51  ? 20.266  -10.398 -15.626 1.000 11.126 0 51  GLY A C   1 ? 
ATOM   164  O O   . GLY A 1 51  ? 20.263  -11.563 -15.265 1.000 14.024 0 51  GLY A O   1 ? 
ATOM   165  N N   . VAL A 1 52  ? 20.039  -10.041 -16.883 1.000 10.440 0 52  VAL A N   1 ? 
ATOM   166  C CA  . VAL A 1 52  ? 19.809  -11.001 -17.937 1.000 11.273 0 52  VAL A CA  1 ? 
ATOM   167  C C   . VAL A 1 52  ? 21.098  -11.184 -18.736 1.000 12.325 0 52  VAL A C   1 ? 
ATOM   168  O O   . VAL A 1 52  ? 21.700  -10.207 -19.205 1.000 11.379 0 52  VAL A O   1 ? 
ATOM   169  C CB  . VAL A 1 52  ? 18.644  -10.581 -18.843 1.000 11.681 0 52  VAL A CB  1 ? 
ATOM   170  C CG1 . VAL A 1 52  ? 18.371  -11.634 -19.894 1.000 12.614 0 52  VAL A CG1 1 ? 
ATOM   171  C CG2 . VAL A 1 52  ? 17.383  -10.291 -18.033 1.000 11.924 0 52  VAL A CG2 1 ? 
ATOM   172  N N   . GLY A 1 53  ? 21.514  -12.453 -18.845 1.000 12.426 0 53  GLY A N   1 ? 
ATOM   173  C CA  . GLY A 1 53  ? 22.722  -12.790 -19.564 1.000 12.406 0 53  GLY A CA  1 ? 
ATOM   174  C C   . GLY A 1 53  ? 22.487  -12.927 -21.066 1.000 12.268 0 53  GLY A C   1 ? 
ATOM   175  O O   . GLY A 1 53  ? 21.360  -12.917 -21.519 1.000 13.069 0 53  GLY A O   1 ? 
ATOM   176  N N   . THR A 1 54  ? 23.579  -13.172 -21.795 1.000 12.724 0 54  THR A N   1 ? 
ATOM   177  C CA  . THR A 1 54  ? 23.548  -13.277 -23.236 1.000 12.624 0 54  THR A CA  1 ? 
ATOM   178  C C   . THR A 1 54  ? 22.698  -14.471 -23.690 1.000 12.927 0 54  THR A C   1 ? 
ATOM   179  O O   . THR A 1 54  ? 22.244  -14.487 -24.834 1.000 15.268 0 54  THR A O   1 ? 
ATOM   180  C CB  . THR A 1 54  ? 24.988  -13.342 -23.747 1.000 14.805 0 54  THR A CB  1 ? 
ATOM   181  O OG1 . THR A 1 54  ? 24.939  -13.180 -25.157 1.000 17.339 0 54  THR A OG1 1 ? 
ATOM   182  C CG2 . THR A 1 54  ? 25.720  -14.587 -23.351 1.000 15.397 0 54  THR A CG2 1 ? 
ATOM   183  N N   . ASN A 1 55  ? 22.547  -15.491 -22.850 1.000 12.567 0 55  ASN A N   1 ? 
ATOM   184  C CA  . ASN A 1 55  ? 21.683  -16.633 -23.131 1.000 12.724 0 55  ASN A CA  1 ? 
ATOM   185  C C   . ASN A 1 55  ? 20.228  -16.432 -22.722 1.000 13.297 0 55  ASN A C   1 ? 
ATOM   186  O O   . ASN A 1 55  ? 19.453  -17.384 -22.762 1.000 14.132 0 55  ASN A O   1 ? 
ATOM   187  C CB  . ASN A 1 55  ? 22.250  -17.908 -22.502 1.000 13.473 0 55  ASN A CB  1 ? 
ATOM   188  C CG  . ASN A 1 55  ? 22.176  -17.916 -20.992 1.000 13.726 0 55  ASN A CG  1 ? 
ATOM   189  O OD1 . ASN A 1 55  ? 22.066  -16.866 -20.354 1.000 13.898 0 55  ASN A OD1 1 ? 
ATOM   190  N ND2 . ASN A 1 55  ? 22.214  -19.100 -20.430 1.000 13.769 0 55  ASN A ND2 1 ? 
ATOM   191  N N   . ASN A 1 56  ? 19.866  -15.193 -22.358 1.000 12.876 0 56  ASN A N   1 ? 
ATOM   192  C CA  . ASN A 1 56  ? 18.496  -14.816 -22.032 1.000 14.101 0 56  ASN A CA  1 ? 
ATOM   193  C C   . ASN A 1 56  ? 18.025  -15.345 -20.687 1.000 16.411 0 56  ASN A C   1 ? 
ATOM   194  O O   . ASN A 1 56  ? 16.855  -15.188 -20.391 1.000 17.556 0 56  ASN A O   1 ? 
ATOM   195  C CB  . ASN A 1 56  ? 17.479  -15.193 -23.111 1.000 14.510 0 56  ASN A CB  1 ? 
ATOM   196  C CG  . ASN A 1 56  ? 17.813  -14.639 -24.461 1.000 18.599 0 56  ASN A CG  1 ? 
ATOM   197  O OD1 . ASN A 1 56  ? 18.077  -15.396 -25.420 1.000 27.087 0 56  ASN A OD1 1 ? 
ATOM   198  N ND2 . ASN A 1 56  ? 17.908  -13.344 -24.525 1.000 15.462 0 56  ASN A ND2 1 ? 
ATOM   199  N N   . ALA A 1 57  ? 18.897  -15.917 -19.862 1.000 12.521 0 57  ALA A N   1 ? 
ATOM   200  C CA  . ALA A 1 57  ? 18.531  -16.330 -18.520 1.000 13.893 0 57  ALA A CA  1 ? 
ATOM   201  C C   . ALA A 1 57  ? 18.849  -15.214 -17.556 1.000 11.909 0 57  ALA A C   1 ? 
ATOM   202  O O   . ALA A 1 57  ? 19.762  -14.426 -17.773 1.000 11.076 0 57  ALA A O   1 ? 
ATOM   203  C CB  . ALA A 1 57  ? 19.271  -17.585 -18.121 1.000 14.805 0 57  ALA A CB  1 ? 
ATOM   204  N N   . VAL A 1 58  ? 18.140  -15.236 -16.421 1.000 13.272 0 58  VAL A N   1 ? 
ATOM   205  C CA  . VAL A 1 58  ? 18.473  -14.399 -15.285 1.000 12.785 0 58  VAL A CA  1 ? 
ATOM   206  C C   . VAL A 1 58  ? 19.671  -15.025 -14.580 1.000 12.840 0 58  VAL A C   1 ? 
ATOM   207  O O   . VAL A 1 58  ? 19.623  -16.203 -14.250 1.000 13.374 0 58  VAL A O   1 ? 
ATOM   208  C CB  . VAL A 1 58  ? 17.295  -14.258 -14.306 1.000 13.827 0 58  VAL A CB  1 ? 
ATOM   209  C CG1 . VAL A 1 58  ? 17.665  -13.495 -13.059 1.000 15.197 0 58  VAL A CG1 1 ? 
ATOM   210  C CG2 . VAL A 1 58  ? 16.066  -13.643 -14.990 1.000 14.767 0 58  VAL A CG2 1 ? 
ATOM   211  N N   . TRP A 1 59  ? 20.732  -14.223 -14.392 1.000 10.804 0 59  TRP A N   1 ? 
ATOM   212  C CA  . TRP A 1 59  ? 21.854  -14.611 -13.555 1.000 12.304 0 59  TRP A CA  1 ? 
ATOM   213  C C   . TRP A 1 59  ? 21.956  -13.688 -12.351 1.000 12.364 0 59  TRP A C   1 ? 
ATOM   214  O O   . TRP A 1 59  ? 21.441  -12.571 -12.330 1.000 11.976 0 59  TRP A O   1 ? 
ATOM   215  C CB  . TRP A 1 59  ? 23.169  -14.547 -14.352 1.000 11.936 0 59  TRP A CB  1 ? 
ATOM   216  C CG  . TRP A 1 59  ? 23.276  -15.433 -15.568 1.000 12.141 0 59  TRP A CG  1 ? 
ATOM   217  C CD1 . TRP A 1 59  ? 22.541  -15.379 -16.710 1.000 12.402 0 59  TRP A CD1 1 ? 
ATOM   218  C CD2 . TRP A 1 59  ? 24.204  -16.524 -15.746 1.000 10.874 0 59  TRP A CD2 1 ? 
ATOM   219  N NE1 . TRP A 1 59  ? 22.966  -16.327 -17.603 1.000 12.698 0 59  TRP A NE1 1 ? 
ATOM   220  C CE2 . TRP A 1 59  ? 23.991  -17.045 -17.045 1.000 11.304 0 59  TRP A CE2 1 ? 
ATOM   221  C CE3 . TRP A 1 59  ? 25.222  -17.077 -14.956 1.000 11.824 0 59  TRP A CE3 1 ? 
ATOM   222  C CZ2 . TRP A 1 59  ? 24.749  -18.116 -17.541 1.000 11.916 0 59  TRP A CZ2 1 ? 
ATOM   223  C CZ3 . TRP A 1 59  ? 25.972  -18.114 -15.452 1.000 11.902 0 59  TRP A CZ3 1 ? 
ATOM   224  C CH2 . TRP A 1 59  ? 25.769  -18.596 -16.745 1.000 12.318 0 59  TRP A CH2 1 ? 
ATOM   225  N N   . HIS A 1 60  ? 22.682  -14.131 -11.314 1.000 11.846 0 60  HIS A N   1 ? 
ATOM   226  C CA  . HIS A 1 60  ? 22.879  -13.332 -10.120 1.000 11.775 0 60  HIS A CA  1 ? 
ATOM   227  C C   . HIS A 1 60  ? 24.295  -13.512 -9.592  1.000 11.223 0 60  HIS A C   1 ? 
ATOM   228  O O   . HIS A 1 60  ? 25.001  -14.444 -9.962  1.000 11.831 0 60  HIS A O   1 ? 
ATOM   229  C CB  . HIS A 1 60  ? 21.798  -13.580 -9.064  1.000 11.800 0 60  HIS A CB  1 ? 
ATOM   230  C CG  . HIS A 1 60  ? 21.738  -14.969 -8.543  1.000 12.573 0 60  HIS A CG  1 ? 
ATOM   231  N ND1 . HIS A 1 60  ? 21.518  -15.180 -7.201  1.000 13.296 0 60  HIS A ND1 1 ? 
ATOM   232  C CD2 . HIS A 1 60  ? 21.889  -16.150 -9.114  1.000 13.255 0 60  HIS A CD2 1 ? 
ATOM   233  C CE1 . HIS A 1 60  ? 21.573  -16.491 -6.987  1.000 14.413 0 60  HIS A CE1 1 ? 
ATOM   234  N NE2 . HIS A 1 60  ? 21.777  -17.109 -8.129  1.000 14.778 0 60  HIS A NE2 1 ? 
ATOM   235  N N   . ASN A 1 61  ? 24.721  -12.536 -8.787  1.000 11.833 0 61  ASN A N   1 ? 
ATOM   236  C CA  . ASN A 1 61  ? 26.072  -12.394 -8.253  1.000 12.517 0 61  ASN A CA  1 ? 
ATOM   237  C C   . ASN A 1 61  ? 25.920  -11.671 -6.928  1.000 11.544 0 61  ASN A C   1 ? 
ATOM   238  O O   . ASN A 1 61  ? 25.067  -10.783 -6.840  1.000 12.131 0 61  ASN A O   1 ? 
ATOM   239  C CB  . ASN A 1 61  ? 26.944  -11.651 -9.263  1.000 12.692 0 61  ASN A CB  1 ? 
ATOM   240  C CG  . ASN A 1 61  ? 28.435  -11.823 -9.055  1.000 14.107 0 61  ASN A CG  1 ? 
ATOM   241  O OD1 . ASN A 1 61  ? 28.906  -12.164 -7.958  1.000 13.955 0 61  ASN A OD1 1 ? 
ATOM   242  N ND2 . ASN A 1 61  ? 29.199  -11.451 -10.066 1.000 15.184 0 61  ASN A ND2 1 ? 
ATOM   243  N N   . TRP A 1 62  ? 26.644  -12.092 -5.882  1.000 11.519 0 62  TRP A N   1 ? 
ATOM   244  C CA  . TRP A 1 62  ? 26.474  -11.515 -4.561  1.000 12.351 0 62  TRP A CA  1 ? 
ATOM   245  C C   . TRP A 1 62  ? 27.815  -11.285 -3.883  1.000 12.466 0 62  TRP A C   1 ? 
ATOM   246  O O   . TRP A 1 62  ? 28.774  -12.014 -4.079  1.000 12.896 0 62  TRP A O   1 ? 
ATOM   247  C CB  . TRP A 1 62  ? 25.580  -12.371 -3.661  1.000 12.101 0 62  TRP A CB  1 ? 
ATOM   248  C CG  . TRP A 1 62  ? 26.016  -13.800 -3.536  1.000 12.048 0 62  TRP A CG  1 ? 
ATOM   249  C CD1 . TRP A 1 62  ? 26.822  -14.334 -2.555  1.000 13.340 0 62  TRP A CD1 1 ? 
ATOM   250  C CD2 . TRP A 1 62  ? 25.651  -14.893 -4.397  1.000 13.299 0 62  TRP A CD2 1 ? 
ATOM   251  N NE1 . TRP A 1 62  ? 26.949  -15.680 -2.737  1.000 13.770 0 62  TRP A NE1 1 ? 
ATOM   252  C CE2 . TRP A 1 62  ? 26.290  -16.045 -3.889  1.000 13.731 0 62  TRP A CE2 1 ? 
ATOM   253  C CE3 . TRP A 1 62  ? 24.904  -14.999 -5.581  1.000 14.441 0 62  TRP A CE3 1 ? 
ATOM   254  C CZ2 . TRP A 1 62  ? 26.158  -17.306 -4.488  1.000 15.229 0 62  TRP A CZ2 1 ? 
ATOM   255  C CZ3 . TRP A 1 62  ? 24.818  -16.223 -6.198  1.000 15.169 0 62  TRP A CZ3 1 ? 
ATOM   256  C CH2 . TRP A 1 62  ? 25.420  -17.363 -5.658  1.000 15.918 0 62  TRP A CH2 1 ? 
ATOM   257  N N   . GLN A 1 63  ? 27.802  -10.312 -2.995  1.000 12.207 0 63  GLN A N   1 ? 
ATOM   258  C CA  . GLN A 1 63  ? 28.885  -10.167 -2.038  1.000 13.292 0 63  GLN A CA  1 ? 
ATOM   259  C C   . GLN A 1 63  ? 28.883  -11.404 -1.155  1.000 14.397 0 63  GLN A C   1 ? 
ATOM   260  O O   . GLN A 1 63  ? 27.823  -11.830 -0.677  1.000 14.262 0 63  GLN A O   1 ? 
ATOM   261  C CB  . GLN A 1 63  ? 28.672  -8.925  -1.173  1.000 13.020 0 63  GLN A CB  1 ? 
ATOM   262  C CG  . GLN A 1 63  ? 28.783  -7.613  -1.948  1.000 12.966 0 63  GLN A CG  1 ? 
ATOM   263  C CD  . GLN A 1 63  ? 28.502  -6.404  -1.084  1.000 13.899 0 63  GLN A CD  1 ? 
ATOM   264  O OE1 . GLN A 1 63  ? 27.678  -6.435  -0.164  1.000 13.328 0 63  GLN A OE1 1 ? 
ATOM   265  N NE2 . GLN A 1 63  ? 29.182  -5.308  -1.364  1.000 15.996 0 63  GLN A NE2 1 ? 
ATOM   266  N N   . THR A 1 64  ? 30.106  -11.920 -0.894  1.000 15.255 0 64  THR A N   1 ? 
ATOM   267  C CA  . THR A 1 64  ? 30.244  -13.057 0.011   1.000 16.572 0 64  THR A CA  1 ? 
ATOM   268  C C   . THR A 1 64  ? 30.274  -12.634 1.489   1.000 18.210 0 64  THR A C   1 ? 
ATOM   269  O O   . THR A 1 64  ? 30.019  -13.467 2.341   1.000 19.610 0 64  THR A O   1 ? 
ATOM   270  C CB  . THR A 1 64  ? 31.536  -13.831 -0.311  1.000 16.103 0 64  THR A CB  1 ? 
ATOM   271  O OG1 . THR A 1 64  ? 32.680  -12.993 -0.131  1.000 18.811 0 64  THR A OG1 1 ? 
ATOM   272  C CG2 . THR A 1 64  ? 31.517  -14.348 -1.723  1.000 19.812 0 64  THR A CG2 1 ? 
ATOM   273  N N   . VAL A 1 65  ? 30.535  -11.360 1.773   1.000 20.281 0 65  VAL A N   1 ? 
ATOM   274  C CA  . VAL A 1 65  ? 30.389  -10.768 3.110   1.000 21.014 0 65  VAL A CA  1 ? 
ATOM   275  C C   . VAL A 1 65  ? 29.965  -9.319  2.934   1.000 21.471 0 65  VAL A C   1 ? 
ATOM   276  O O   . VAL A 1 65  ? 30.244  -8.685  1.927   1.000 21.299 0 65  VAL A O   1 ? 
ATOM   277  C CB  . VAL A 1 65  ? 31.717  -10.783 3.885   1.000 26.043 0 65  VAL A CB  1 ? 
ATOM   278  C CG1 . VAL A 1 65  ? 32.177  -12.203 4.109   1.000 28.546 0 65  VAL A CG1 1 ? 
ATOM   279  C CG2 . VAL A 1 65  ? 32.770  -9.944  3.172   1.000 24.083 0 65  VAL A CG2 1 ? 
ATOM   280  N N   . PRO A 1 66  ? 29.273  -8.725  3.898   1.000 21.283 0 66  PRO A N   1 ? 
ATOM   281  C CA  . PRO A 1 66  ? 28.798  -7.350  3.700   1.000 21.210 0 66  PRO A CA  1 ? 
ATOM   282  C C   . PRO A 1 66  ? 29.957  -6.360  3.516   1.000 21.969 0 66  PRO A C   1 ? 
ATOM   283  O O   . PRO A 1 66  ? 31.056  -6.611  3.998   1.000 23.027 0 66  PRO A O   1 ? 
ATOM   284  C CB  . PRO A 1 66  ? 27.992  -7.078  4.987   1.000 24.265 0 66  PRO A CB  1 ? 
ATOM   285  C CG  . PRO A 1 66  ? 27.769  -8.451  5.612   1.000 23.598 0 66  PRO A CG  1 ? 
ATOM   286  C CD  . PRO A 1 66  ? 28.927  -9.329  5.191   1.000 23.688 0 66  PRO A CD  1 ? 
ATOM   287  N N   . ASN A 1 67  ? 29.719  -5.277  2.747   1.000 20.168 0 67  ASN A N   1 ? 
ATOM   288  C CA  . ASN A 1 67  ? 30.575  -4.098  2.670   1.000 22.598 0 67  ASN A CA  1 ? 
ATOM   289  C C   . ASN A 1 67  ? 31.843  -4.280  1.826   1.000 22.326 0 67  ASN A C   1 ? 
ATOM   290  O O   . ASN A 1 67  ? 32.622  -3.332  1.681   1.000 24.827 0 67  ASN A O   1 ? 
ATOM   291  C CB  . ASN A 1 67  ? 31.018  -3.596  4.058   1.000 20.862 0 67  ASN A CB  1 ? 
ATOM   292  C CG  . ASN A 1 67  ? 29.837  -3.229  4.925   1.000 22.434 0 67  ASN A CG  1 ? 
ATOM   293  O OD1 . ASN A 1 67  ? 28.859  -2.667  4.442   1.000 21.835 0 67  ASN A OD1 1 ? 
ATOM   294  N ND2 . ASN A 1 67  ? 29.899  -3.571  6.201   1.000 25.451 0 67  ASN A ND2 1 ? 
ATOM   295  N N   . THR A 1 68  ? 32.110  -5.487  1.327   1.000 22.020 0 68  THR A N   1 ? 
ATOM   296  C CA  . THR A 1 68  ? 33.348  -5.775  0.604   1.000 21.770 0 68  THR A CA  1 ? 
ATOM   297  C C   . THR A 1 68  ? 33.444  -4.901  -0.653  1.000 24.693 0 68  THR A C   1 ? 
ATOM   298  O O   . THR A 1 68  ? 32.424  -4.580  -1.253  1.000 24.800 0 68  THR A O   1 ? 
ATOM   299  C CB  . THR A 1 68  ? 33.384  -7.263  0.228   1.000 23.538 0 68  THR A CB  1 ? 
ATOM   300  O OG1 . THR A 1 68  ? 34.620  -7.564  -0.408  1.000 22.991 0 68  THR A OG1 1 ? 
ATOM   301  C CG2 . THR A 1 68  ? 32.292  -7.697  -0.734  1.000 24.914 0 68  THR A CG2 1 ? 
ATOM   302  N N   . GLY A 1 69  ? 34.678  -4.577  -1.067  1.000 25.536 0 69  GLY A N   1 ? 
ATOM   303  C CA  . GLY A 1 69  ? 34.953  -3.988  -2.370  1.000 27.963 0 69  GLY A CA  1 ? 
ATOM   304  C C   . GLY A 1 69  ? 35.008  -4.997  -3.512  1.000 27.574 0 69  GLY A C   1 ? 
ATOM   305  O O   . GLY A 1 69  ? 34.654  -4.660  -4.650  1.000 36.851 0 69  GLY A O   1 ? 
ATOM   306  N N   . SER A 1 70  ? 35.499  -6.220  -3.271  1.000 25.988 0 70  SER A N   1 ? 
ATOM   307  C CA  . SER A 1 70  ? 35.870  -7.085  -4.377  1.000 25.966 0 70  SER A CA  1 ? 
ATOM   308  C C   . SER A 1 70  ? 35.491  -8.553  -4.167  1.000 23.078 0 70  SER A C   1 ? 
ATOM   309  O O   . SER A 1 70  ? 35.568  -9.329  -5.125  1.000 25.081 0 70  SER A O   1 ? 
ATOM   310  C CB  . SER A 1 70  ? 37.343  -6.949  -4.678  1.000 31.548 0 70  SER A CB  1 ? 
ATOM   311  O OG  . SER A 1 70  ? 38.086  -7.231  -3.511  1.000 37.517 0 70  SER A OG  1 ? 
ATOM   312  N N   . SER A 1 71  ? 35.001  -8.943  -2.978  1.000 21.772 0 71  SER A N   1 ? 
ATOM   313  C CA  . SER A 1 71  ? 34.762  -10.353 -2.734  1.000 18.677 0 71  SER A CA  1 ? 
ATOM   314  C C   . SER A 1 71  ? 33.320  -10.705 -3.112  1.000 16.698 0 71  SER A C   1 ? 
ATOM   315  O O   . SER A 1 71  ? 32.393  -10.646 -2.280  1.000 16.143 0 71  SER A O   1 ? 
ATOM   316  C CB  . SER A 1 71  ? 35.012  -10.710 -1.292  1.000 18.796 0 71  SER A CB  1 ? 
ATOM   317  O OG  . SER A 1 71  ? 34.968  -12.133 -1.155  1.000 23.411 0 71  SER A OG  1 ? 
ATOM   318  N N   . TRP A 1 72  ? 33.177  -11.058 -4.384  1.000 15.135 0 72  TRP A N   1 ? 
ATOM   319  C CA  . TRP A 1 72  ? 31.901  -11.489 -4.920  1.000 14.361 0 72  TRP A CA  1 ? 
ATOM   320  C C   . TRP A 1 72  ? 31.926  -12.974 -5.278  1.000 14.668 0 72  TRP A C   1 ? 
ATOM   321  O O   . TRP A 1 72  ? 32.977  -13.576 -5.529  1.000 15.275 0 72  TRP A O   1 ? 
ATOM   322  C CB  . TRP A 1 72  ? 31.545  -10.631 -6.135  1.000 13.655 0 72  TRP A CB  1 ? 
ATOM   323  C CG  . TRP A 1 72  ? 31.119  -9.248  -5.749  1.000 13.375 0 72  TRP A CG  1 ? 
ATOM   324  C CD1 . TRP A 1 72  ? 31.921  -8.259  -5.255  1.000 14.725 0 72  TRP A CD1 1 ? 
ATOM   325  C CD2 . TRP A 1 72  ? 29.806  -8.666  -5.848  1.000 11.958 0 72  TRP A CD2 1 ? 
ATOM   326  N NE1 . TRP A 1 72  ? 31.190  -7.119  -5.039  1.000 14.328 0 72  TRP A NE1 1 ? 
ATOM   327  C CE2 . TRP A 1 72  ? 29.890  -7.348  -5.387  1.000 12.661 0 72  TRP A CE2 1 ? 
ATOM   328  C CE3 . TRP A 1 72  ? 28.564  -9.169  -6.260  1.000 12.522 0 72  TRP A CE3 1 ? 
ATOM   329  C CZ2 . TRP A 1 72  ? 28.787  -6.504  -5.354  1.000 13.189 0 72  TRP A CZ2 1 ? 
ATOM   330  C CZ3 . TRP A 1 72  ? 27.470  -8.327  -6.250  1.000 13.756 0 72  TRP A CZ3 1 ? 
ATOM   331  C CH2 . TRP A 1 72  ? 27.585  -7.032  -5.756  1.000 12.065 0 72  TRP A CH2 1 ? 
ATOM   332  N N   . SER A 1 73  ? 30.732  -13.581 -5.333  1.000 13.407 0 73  SER A N   1 ? 
ATOM   333  C CA  . SER A 1 73  ? 30.557  -14.973 -5.663  1.000 12.973 0 73  SER A CA  1 ? 
ATOM   334  C C   . SER A 1 73  ? 30.959  -15.328 -7.088  1.000 14.197 0 73  SER A C   1 ? 
ATOM   335  O O   . SER A 1 73  ? 31.344  -16.470 -7.359  1.000 17.679 0 73  SER A O   1 ? 
ATOM   336  C CB  . SER A 1 73  ? 29.123  -15.364 -5.436  1.000 13.537 0 73  SER A CB  1 ? 
ATOM   337  O OG  . SER A 1 73  ? 28.247  -14.658 -6.321  1.000 13.846 0 73  SER A OG  1 ? 
ATOM   338  N N   . GLY A 1 74  ? 30.848  -14.381 -7.987  1.000 13.654 0 74  GLY A N   1 ? 
ATOM   339  C CA  . GLY A 1 74  ? 30.780  -14.660 -9.403  1.000 15.043 0 74  GLY A CA  1 ? 
ATOM   340  C C   . GLY A 1 74  ? 29.352  -15.030 -9.799  1.000 14.425 0 74  GLY A C   1 ? 
ATOM   341  O O   . GLY A 1 74  ? 28.489  -15.237 -8.954  1.000 15.403 0 74  GLY A O   1 ? 
ATOM   342  N N   . TRP A 1 75  ? 29.142  -15.072 -11.120 1.000 13.947 0 75  TRP A N   1 ? 
ATOM   343  C CA  . TRP A 1 75  ? 27.812  -15.185 -11.693 1.000 12.631 0 75  TRP A CA  1 ? 
ATOM   344  C C   . TRP A 1 75  ? 27.308  -16.628 -11.687 1.000 14.034 0 75  TRP A C   1 ? 
ATOM   345  O O   . TRP A 1 75  ? 27.994  -17.524 -12.146 1.000 15.189 0 75  TRP A O   1 ? 
ATOM   346  C CB  . TRP A 1 75  ? 27.833  -14.667 -13.134 1.000 13.527 0 75  TRP A CB  1 ? 
ATOM   347  C CG  . TRP A 1 75  ? 28.008  -13.164 -13.207 1.000 13.851 0 75  TRP A CG  1 ? 
ATOM   348  C CD1 . TRP A 1 75  ? 29.166  -12.467 -13.425 1.000 15.524 0 75  TRP A CD1 1 ? 
ATOM   349  C CD2 . TRP A 1 75  ? 26.977  -12.173 -13.054 1.000 14.061 0 75  TRP A CD2 1 ? 
ATOM   350  N NE1 . TRP A 1 75  ? 28.909  -11.131 -13.379 1.000 14.430 0 75  TRP A NE1 1 ? 
ATOM   351  C CE2 . TRP A 1 75  ? 27.580  -10.901 -13.185 1.000 12.457 0 75  TRP A CE2 1 ? 
ATOM   352  C CE3 . TRP A 1 75  ? 25.613  -12.224 -12.794 1.000 12.965 0 75  TRP A CE3 1 ? 
ATOM   353  C CZ2 . TRP A 1 75  ? 26.832  -9.722  -13.088 1.000 13.696 0 75  TRP A CZ2 1 ? 
ATOM   354  C CZ3 . TRP A 1 75  ? 24.895  -11.064 -12.665 1.000 13.951 0 75  TRP A CZ3 1 ? 
ATOM   355  C CH2 . TRP A 1 75  ? 25.490  -9.820  -12.813 1.000 13.994 0 75  TRP A CH2 1 ? 
ATOM   356  N N   . HIS A 1 76  ? 26.056  -16.779 -11.259 1.000 12.807 0 76  HIS A N   1 ? 
ATOM   357  C CA  . HIS A 1 76  ? 25.361  -18.053 -11.186 1.000 13.284 0 76  HIS A CA  1 ? 
ATOM   358  C C   . HIS A 1 76  ? 24.031  -17.904 -11.905 1.000 11.922 0 76  HIS A C   1 ? 
ATOM   359  O O   . HIS A 1 76  ? 23.365  -16.867 -11.811 1.000 13.033 0 76  HIS A O   1 ? 
ATOM   360  C CB  . HIS A 1 76  ? 25.178  -18.493 -9.722  1.000 15.539 0 76  HIS A CB  1 ? 
ATOM   361  C CG  . HIS A 1 76  ? 26.427  -18.901 -9.051  1.000 19.476 0 76  HIS A CG  1 ? 
ATOM   362  N ND1 . HIS A 1 76  ? 26.855  -20.210 -9.105  1.000 26.345 0 76  HIS A ND1 1 ? 
ATOM   363  C CD2 . HIS A 1 76  ? 27.361  -18.243 -8.386  1.000 19.524 0 76  HIS A CD2 1 ? 
ATOM   364  C CE1 . HIS A 1 76  ? 28.027  -20.323 -8.493  1.000 25.573 0 76  HIS A CE1 1 ? 
ATOM   365  N NE2 . HIS A 1 76  ? 28.332  -19.174 -7.996  1.000 20.594 0 76  HIS A NE2 1 ? 
ATOM   366  N N   . SER A 1 77  ? 23.612  -18.930 -12.634 1.000 12.612 0 77  SER A N   1 ? 
ATOM   367  C CA  . SER A 1 77  ? 22.413  -18.861 -13.448 1.000 12.899 0 77  SER A CA  1 ? 
ATOM   368  C C   . SER A 1 77  ? 21.194  -19.294 -12.646 1.000 13.778 0 77  SER A C   1 ? 
ATOM   369  O O   . SER A 1 77  ? 21.269  -20.250 -11.869 1.000 14.088 0 77  SER A O   1 ? 
ATOM   370  C CB  . SER A 1 77  ? 22.499  -19.728 -14.662 1.000 12.685 0 77  SER A CB  1 ? 
ATOM   371  O OG  . SER A 1 77  ? 21.351  -19.571 -15.472 1.000 13.507 0 77  SER A OG  1 ? 
ATOM   372  N N   . LEU A 1 78  ? 20.066  -18.599 -12.864 1.000 12.073 0 78  LEU A N   1 ? 
ATOM   373  C CA  . LEU A 1 78  ? 18.799  -19.086 -12.386 1.000 13.507 0 78  LEU A CA  1 ? 
ATOM   374  C C   . LEU A 1 78  ? 18.000  -19.776 -13.490 1.000 15.658 0 78  LEU A C   1 ? 
ATOM   375  O O   . LEU A 1 78  ? 16.848  -20.121 -13.253 1.000 16.855 0 78  LEU A O   1 ? 
ATOM   376  C CB  . LEU A 1 78  ? 18.009  -17.913 -11.788 1.000 15.120 0 78  LEU A CB  1 ? 
ATOM   377  C CG  . LEU A 1 78  ? 18.497  -17.399 -10.452 1.000 16.450 0 78  LEU A CG  1 ? 
ATOM   378  C CD1 . LEU A 1 78  ? 17.665  -16.180 -10.087 1.000 20.074 0 78  LEU A CD1 1 ? 
ATOM   379  C CD2 . LEU A 1 78  ? 18.453  -18.452 -9.362  1.000 17.141 0 78  LEU A CD2 1 ? 
ATOM   380  N N   . ASN A 1 79  ? 18.577  -19.955 -14.685 1.000 15.468 0 79  ASN A N   1 ? 
ATOM   381  C CA  . ASN A 1 79  ? 17.993  -20.708 -15.791 1.000 19.806 0 79  ASN A CA  1 ? 
ATOM   382  C C   . ASN A 1 79  ? 16.702  -20.132 -16.360 1.000 24.784 0 79  ASN A C   1 ? 
ATOM   383  O O   . ASN A 1 79  ? 16.194  -19.144 -15.885 1.000 23.399 0 79  ASN A O   1 ? 
ATOM   384  C CB  . ASN A 1 79  ? 17.690  -22.152 -15.393 1.000 22.868 0 79  ASN A CB  1 ? 
ATOM   385  C CG  . ASN A 1 79  ? 18.914  -22.813 -14.820 1.000 26.931 0 79  ASN A CG  1 ? 
ATOM   386  O OD1 . ASN A 1 79  ? 18.900  -23.199 -13.654 1.000 39.518 0 79  ASN A OD1 1 ? 
ATOM   387  N ND2 . ASN A 1 79  ? 19.947  -22.967 -15.629 1.000 28.941 0 79  ASN A ND2 1 ? 
ATOM   388  N N   . GLU A 1 80  ? 16.219  -20.800 -17.418 1.000 28.103 0 80  GLU A N   1 ? 
ATOM   389  C CA  . GLU A 1 80  ? 14.999  -20.441 -18.132 1.000 30.555 0 80  GLU A CA  1 ? 
ATOM   390  C C   . GLU A 1 80  ? 15.271  -19.120 -18.861 1.000 31.225 0 80  GLU A C   1 ? 
ATOM   391  O O   . GLU A 1 80  ? 16.429  -18.809 -19.157 1.000 32.071 0 80  GLU A O   1 ? 
ATOM   392  C CB  . GLU A 1 80  ? 13.778  -20.495 -17.197 1.000 31.609 0 80  GLU A CB  1 ? 
ATOM   393  N N   . GLY A 1 81  ? 14.213  -18.360 -19.148 1.000 27.317 0 81  GLY A N   1 ? 
ATOM   394  C CA  . GLY A 1 81  ? 14.252  -17.393 -20.227 1.000 22.489 0 81  GLY A CA  1 ? 
ATOM   395  C C   . GLY A 1 81  ? 13.487  -16.146 -19.808 1.000 22.498 0 81  GLY A C   1 ? 
ATOM   396  O O   . GLY A 1 81  ? 12.309  -16.246 -19.473 1.000 24.159 0 81  GLY A O   1 ? 
ATOM   397  N N   . ALA A 1 82  ? 14.161  -15.003 -19.878 1.000 16.461 0 82  ALA A N   1 ? 
ATOM   398  C CA  . ALA A 1 82  ? 13.672  -13.702 -19.427 1.000 15.142 0 82  ALA A CA  1 ? 
ATOM   399  C C   . ALA A 1 82  ? 13.434  -12.784 -20.625 1.000 13.784 0 82  ALA A C   1 ? 
ATOM   400  O O   . ALA A 1 82  ? 14.168  -12.830 -21.634 1.000 16.373 0 82  ALA A O   1 ? 
ATOM   401  C CB  . ALA A 1 82  ? 14.664  -13.108 -18.480 1.000 17.770 0 82  ALA A CB  1 ? 
ATOM   402  N N   . THR A 1 83  ? 12.386  -11.969 -20.545 1.000 13.175 0 83  THR A N   1 ? 
ATOM   403  C CA  . THR A 1 83  ? 12.060  -11.008 -21.590 1.000 12.958 0 83  THR A CA  1 ? 
ATOM   404  C C   . THR A 1 83  ? 11.735  -9.645  -20.986 1.000 11.986 0 83  THR A C   1 ? 
ATOM   405  O O   . THR A 1 83  ? 11.123  -8.790  -21.617 1.000 13.815 0 83  THR A O   1 ? 
ATOM   406  C CB  . THR A 1 83  ? 10.873  -11.451 -22.456 1.000 13.139 0 83  THR A CB  1 ? 
ATOM   407  O OG1 . THR A 1 83  ? 9.725   -11.489 -21.604 1.000 12.968 0 83  THR A OG1 1 ? 
ATOM   408  C CG2 . THR A 1 83  ? 11.081  -12.803 -23.118 1.000 14.229 0 83  THR A CG2 1 ? 
ATOM   409  N N   . SER A 1 84  ? 12.217  -9.399  -19.758 1.000 12.497 0 84  SER A N   1 ? 
ATOM   410  C CA  . SER A 1 84  ? 12.211  -8.064  -19.187 1.000 12.067 0 84  SER A CA  1 ? 
ATOM   411  C C   . SER A 1 84  ? 13.431  -7.893  -18.298 1.000 11.019 0 84  SER A C   1 ? 
ATOM   412  O O   . SER A 1 84  ? 14.154  -8.843  -18.027 1.000 11.021 0 84  SER A O   1 ? 
ATOM   413  C CB  . SER A 1 84  ? 10.983  -7.754  -18.372 1.000 11.663 0 84  SER A CB  1 ? 
ATOM   414  O OG  . SER A 1 84  ? 10.994  -8.444  -17.123 1.000 11.361 0 84  SER A OG  1 ? 
ATOM   415  N N   . LYS A 1 85  ? 13.647  -6.656  -17.853 1.000 11.903 0 85  LYS A N   1 ? 
ATOM   416  C CA  . LYS A 1 85  ? 14.560  -6.422  -16.758 1.000 12.525 0 85  LYS A CA  1 ? 
ATOM   417  C C   . LYS A 1 85  ? 13.981  -7.112  -15.534 1.000 12.443 0 85  LYS A C   1 ? 
ATOM   418  O O   . LYS A 1 85  ? 12.782  -7.067  -15.261 1.000 11.713 0 85  LYS A O   1 ? 
ATOM   419  C CB  . LYS A 1 85  ? 14.685  -4.915  -16.517 1.000 13.300 0 85  LYS A CB  1 ? 
ATOM   420  C CG  . LYS A 1 85  ? 15.676  -4.482  -15.439 1.000 14.682 0 85  LYS A CG  1 ? 
ATOM   421  C CD  . LYS A 1 85  ? 15.612  -2.974  -15.250 1.000 16.562 0 85  LYS A CD  1 ? 
ATOM   422  C CE  . LYS A 1 85  ? 16.667  -2.416  -14.303 1.000 21.033 0 85  LYS A CE  1 ? 
ATOM   423  N NZ  . LYS A 1 85  ? 16.269  -2.338  -12.874 1.000 23.482 0 85  LYS A NZ  1 ? 
ATOM   424  N N   . PRO A 1 86  ? 14.813  -7.830  -14.762 1.000 11.624 0 86  PRO A N   1 ? 
ATOM   425  C CA  . PRO A 1 86  ? 14.351  -8.388  -13.499 1.000 11.610 0 86  PRO A CA  1 ? 
ATOM   426  C C   . PRO A 1 86  ? 14.226  -7.355  -12.409 1.000 11.973 0 86  PRO A C   1 ? 
ATOM   427  O O   . PRO A 1 86  ? 14.851  -6.308  -12.491 1.000 13.399 0 86  PRO A O   1 ? 
ATOM   428  C CB  . PRO A 1 86  ? 15.416  -9.416  -13.121 1.000 12.969 0 86  PRO A CB  1 ? 
ATOM   429  C CG  . PRO A 1 86  ? 16.629  -9.061  -13.931 1.000 13.953 0 86  PRO A CG  1 ? 
ATOM   430  C CD  . PRO A 1 86  ? 16.218  -8.109  -15.023 1.000 11.883 0 86  PRO A CD  1 ? 
ATOM   431  N N   . ALA A 1 87  ? 13.429  -7.698  -11.407 1.000 10.816 0 87  ALA A N   1 ? 
ATOM   432  C CA  . ALA A 1 87  ? 13.262  -6.882  -10.219 1.000 10.292 0 87  ALA A CA  1 ? 
ATOM   433  C C   . ALA A 1 87  ? 13.316  -7.741  -8.975  1.000 11.019 0 87  ALA A C   1 ? 
ATOM   434  O O   . ALA A 1 87  ? 12.670  -8.758  -8.937  1.000 12.004 0 87  ALA A O   1 ? 
ATOM   435  C CB  . ALA A 1 87  ? 11.938  -6.129  -10.237 1.000 11.353 0 87  ALA A CB  1 ? 
ATOM   436  N N   . VAL A 1 88  ? 14.135  -7.352  -8.006  1.000 12.085 0 88  VAL A N   1 ? 
ATOM   437  C CA  . VAL A 1 88  ? 14.248  -8.103  -6.755  1.000 12.290 0 88  VAL A CA  1 ? 
ATOM   438  C C   . VAL A 1 88  ? 13.816  -7.253  -5.579  1.000 11.697 0 88  VAL A C   1 ? 
ATOM   439  O O   . VAL A 1 88  ? 14.026  -6.037  -5.551  1.000 12.528 0 88  VAL A O   1 ? 
ATOM   440  C CB  . VAL A 1 88  ? 15.684  -8.646  -6.581  1.000 12.512 0 88  VAL A CB  1 ? 
ATOM   441  C CG1 . VAL A 1 88  ? 16.745  -7.543  -6.547  1.000 13.227 0 88  VAL A CG1 1 ? 
ATOM   442  C CG2 . VAL A 1 88  ? 15.848  -9.530  -5.340  1.000 13.160 0 88  VAL A CG2 1 ? 
ATOM   443  N N   . HIS A 1 89  ? 13.213  -7.936  -4.590  1.000 11.452 0 89  HIS A N   1 ? 
ATOM   444  C CA  . HIS A 1 89  ? 12.887  -7.305  -3.329  1.000 12.153 0 89  HIS A CA  1 ? 
ATOM   445  C C   . HIS A 1 89  ? 13.038  -8.357  -2.233  1.000 12.125 0 89  HIS A C   1 ? 
ATOM   446  O O   . HIS A 1 89  ? 12.714  -9.522  -2.443  1.000 12.154 0 89  HIS A O   1 ? 
ATOM   447  C CB  . HIS A 1 89  ? 11.449  -6.741  -3.342  1.000 13.088 0 89  HIS A CB  1 ? 
ATOM   448  C CG  . HIS A 1 89  ? 11.248  -5.645  -2.362  1.000 14.929 0 89  HIS A CG  1 ? 
ATOM   449  N ND1 . HIS A 1 89  ? 11.246  -5.822  -0.977  1.000 17.832 0 89  HIS A ND1 1 ? 
ATOM   450  C CD2 . HIS A 1 89  ? 11.043  -4.307  -2.576  1.000 17.516 0 89  HIS A CD2 1 ? 
ATOM   451  C CE1 . HIS A 1 89  ? 11.120  -4.633  -0.398  1.000 19.006 0 89  HIS A CE1 1 ? 
ATOM   452  N NE2 . HIS A 1 89  ? 10.972  -3.714  -1.337  1.000 19.981 0 89  HIS A NE2 1 ? 
ATOM   453  N N   . ILE A 1 90  ? 13.444  -7.933  -1.024  1.000 14.776 0 90  ILE A N   1 ? 
ATOM   454  C CA  . ILE A 1 90  ? 13.462  -8.843  0.103   1.000 14.007 0 90  ILE A CA  1 ? 
ATOM   455  C C   . ILE A 1 90  ? 12.038  -8.960  0.636   1.000 13.725 0 90  ILE A C   1 ? 
ATOM   456  O O   . ILE A 1 90  ? 11.267  -8.011  0.639   1.000 13.302 0 90  ILE A O   1 ? 
ATOM   457  C CB  . ILE A 1 90  ? 14.459  -8.364  1.168   1.000 15.564 0 90  ILE A CB  1 ? 
ATOM   458  C CG1 . ILE A 1 90  ? 14.861  -9.495  2.121   1.000 15.303 0 90  ILE A CG1 1 ? 
ATOM   459  C CG2 . ILE A 1 90  ? 13.913  -7.171  1.937   1.000 15.345 0 90  ILE A CG2 1 ? 
ATOM   460  C CD1 . ILE A 1 90  ? 16.122  -9.195  2.906   1.000 16.866 0 90  ILE A CD1 1 ? 
ATOM   461  N N   . ASN A 1 91  ? 11.700  -10.153 1.089   1.000 12.999 0 91  ASN A N   1 ? 
ATOM   462  C CA  . ASN A 1 91  ? 10.510  -10.350 1.903   1.000 13.985 0 91  ASN A CA  1 ? 
ATOM   463  C C   . ASN A 1 91  ? 10.749  -9.932  3.358   1.000 14.291 0 91  ASN A C   1 ? 
ATOM   464  O O   . ASN A 1 91  ? 11.873  -9.749  3.793   1.000 15.751 0 91  ASN A O   1 ? 
ATOM   465  C CB  . ASN A 1 91  ? 10.079  -11.809 1.878   1.000 13.844 0 91  ASN A CB  1 ? 
ATOM   466  C CG  . ASN A 1 91  ? 9.372   -12.232 0.600   1.000 13.643 0 91  ASN A CG  1 ? 
ATOM   467  O OD1 . ASN A 1 91  ? 8.154   -12.104 0.485   1.000 14.469 0 91  ASN A OD1 1 ? 
ATOM   468  N ND2 . ASN A 1 91  ? 10.117  -12.824 -0.316  1.000 13.858 0 91  ASN A ND2 1 ? 
ATOM   469  N N   . SER A 1 92  ? 9.642   -9.788  4.086   1.000 15.178 0 92  SER A N   1 ? 
ATOM   470  C CA  . SER A 1 92  ? 9.672   -9.335  5.475   1.000 16.391 0 92  SER A CA  1 ? 
ATOM   471  C C   . SER A 1 92  ? 10.228  -10.426 6.396   1.000 18.135 0 92  SER A C   1 ? 
ATOM   472  O O   . SER A 1 92  ? 10.456  -10.134 7.566   1.000 23.478 0 92  SER A O   1 ? 
ATOM   473  C CB  . SER A 1 92  ? 8.319   -8.855  5.950   1.000 18.255 0 92  SER A CB  1 ? 
ATOM   474  O OG  . SER A 1 92  ? 7.354   -9.856  5.758   1.000 19.882 0 92  SER A OG  1 ? 
ATOM   475  N N   . ASP A 1 93  ? 10.450  -11.639 5.892   1.000 15.644 0 93  ASP A N   1 ? 
ATOM   476  C CA  . ASP A 1 93  ? 11.136  -12.708 6.646   1.000 15.865 0 93  ASP A CA  1 ? 
ATOM   477  C C   . ASP A 1 93  ? 12.606  -12.899 6.232   1.000 17.183 0 93  ASP A C   1 ? 
ATOM   478  O O   . ASP A 1 93  ? 13.240  -13.896 6.598   1.000 17.101 0 93  ASP A O   1 ? 
ATOM   479  C CB  . ASP A 1 93  ? 10.383  -14.028 6.498   1.000 16.085 0 93  ASP A CB  1 ? 
ATOM   480  C CG  . ASP A 1 93  ? 10.320  -14.569 5.085   1.000 17.691 0 93  ASP A CG  1 ? 
ATOM   481  O OD1 . ASP A 1 93  ? 10.930  -13.906 4.196   1.000 16.394 0 93  ASP A OD1 1 ? 
ATOM   482  O OD2 . ASP A 1 93  ? 9.664   -15.619 4.859   1.000 19.052 0 93  ASP A OD2 1 ? 
ATOM   483  N N   . GLY A 1 94  ? 13.121  -11.986 5.394   1.000 15.727 0 94  GLY A N   1 ? 
ATOM   484  C CA  . GLY A 1 94  ? 14.526  -12.009 5.006   1.000 15.463 0 94  GLY A CA  1 ? 
ATOM   485  C C   . GLY A 1 94  ? 14.869  -12.705 3.690   1.000 15.466 0 94  GLY A C   1 ? 
ATOM   486  O O   . GLY A 1 94  ? 16.056  -12.722 3.345   1.000 15.202 0 94  GLY A O   1 ? 
ATOM   487  N N   . ARG A 1 95  ? 13.915  -13.373 3.030   1.000 13.046 0 95  ARG A N   1 ? 
ATOM   488  C CA  . ARG A 1 95  ? 14.169  -14.082 1.790   1.000 13.236 0 95  ARG A CA  1 ? 
ATOM   489  C C   . ARG A 1 95  ? 14.086  -13.149 0.580   1.000 12.485 0 95  ARG A C   1 ? 
ATOM   490  O O   . ARG A 1 95  ? 13.056  -12.507 0.349   1.000 13.615 0 95  ARG A O   1 ? 
ATOM   491  C CB  . ARG A 1 95  ? 13.143  -15.197 1.649   1.000 12.753 0 95  ARG A CB  1 ? 
ATOM   492  C CG  . ARG A 1 95  ? 13.221  -16.214 2.798   1.000 14.177 0 95  ARG A CG  1 ? 
ATOM   493  C CD  . ARG A 1 95  ? 12.216  -17.349 2.641   1.000 14.680 0 95  ARG A CD  1 ? 
ATOM   494  N NE  . ARG A 1 95  ? 10.851  -16.845 2.697   1.000 16.210 0 95  ARG A NE  1 ? 
ATOM   495  C CZ  . ARG A 1 95  ? 10.063  -16.591 1.652   1.000 15.488 0 95  ARG A CZ  1 ? 
ATOM   496  N NH1 . ARG A 1 95  ? 10.474  -16.775 0.406   1.000 15.427 0 95  ARG A NH1 1 ? 
ATOM   497  N NH2 . ARG A 1 95  ? 8.898   -16.004 1.862   1.000 16.058 0 95  ARG A NH2 1 ? 
ATOM   498  N N   . LEU A 1 96  ? 15.127  -13.142 -0.249  1.000 11.669 0 96  LEU A N   1 ? 
ATOM   499  C CA  . LEU A 1 96  ? 15.029  -12.393 -1.492  1.000 12.225 0 96  LEU A CA  1 ? 
ATOM   500  C C   . LEU A 1 96  ? 14.073  -13.086 -2.453  1.000 12.025 0 96  LEU A C   1 ? 
ATOM   501  O O   . LEU A 1 96  ? 13.997  -14.299 -2.493  1.000 12.377 0 96  LEU A O   1 ? 
ATOM   502  C CB  . LEU A 1 96  ? 16.399  -12.320 -2.163  1.000 12.500 0 96  LEU A CB  1 ? 
ATOM   503  C CG  . LEU A 1 96  ? 17.461  -11.475 -1.472  1.000 12.881 0 96  LEU A CG  1 ? 
ATOM   504  C CD1 . LEU A 1 96  ? 18.672  -11.371 -2.393  1.000 12.620 0 96  LEU A CD1 1 ? 
ATOM   505  C CD2 . LEU A 1 96  ? 16.964  -10.119 -1.113  1.000 14.187 0 96  LEU A CD2 1 ? 
ATOM   506  N N   . GLU A 1 97  ? 13.450  -12.297 -3.342  1.000 11.980 0 97  GLU A N   1 ? 
ATOM   507  C CA  . GLU A 1 97  ? 12.520  -12.815 -4.328  1.000 11.477 0 97  GLU A CA  1 ? 
ATOM   508  C C   . GLU A 1 97  ? 12.664  -11.953 -5.589  1.000 11.151 0 97  GLU A C   1 ? 
ATOM   509  O O   . GLU A 1 97  ? 12.605  -10.719 -5.539  1.000 10.625 0 97  GLU A O   1 ? 
ATOM   510  C CB  . GLU A 1 97  ? 11.103  -12.781 -3.757  1.000 13.030 0 97  GLU A CB  1 ? 
ATOM   511  C CG  . GLU A 1 97  ? 10.060  -13.419 -4.625  1.000 12.669 0 97  GLU A CG  1 ? 
ATOM   512  C CD  . GLU A 1 97  ? 8.820   -13.863 -3.861  1.000 13.341 0 97  GLU A CD  1 ? 
ATOM   513  O OE1 . GLU A 1 97  ? 8.852   -13.914 -2.625  1.000 13.031 0 97  GLU A OE1 1 ? 
ATOM   514  O OE2 . GLU A 1 97  ? 7.764   -14.032 -4.515  1.000 12.838 0 97  GLU A OE2 1 ? 
ATOM   515  N N   . VAL A 1 98  ? 12.881  -12.620 -6.701  1.000 11.343 0 98  VAL A N   1 ? 
ATOM   516  C CA  . VAL A 1 98  ? 13.095  -11.968 -7.979  1.000 11.347 0 98  VAL A CA  1 ? 
ATOM   517  C C   . VAL A 1 98  ? 11.929  -12.238 -8.929  1.000 11.245 0 98  VAL A C   1 ? 
ATOM   518  O O   . VAL A 1 98  ? 11.363  -13.326 -8.954  1.000 10.452 0 98  VAL A O   1 ? 
ATOM   519  C CB  . VAL A 1 98  ? 14.470  -12.347 -8.597  1.000 12.396 0 98  VAL A CB  1 ? 
ATOM   520  C CG1 . VAL A 1 98  ? 14.600  -13.826 -8.918  1.000 14.313 0 98  VAL A CG1 1 ? 
ATOM   521  C CG2 . VAL A 1 98  ? 14.799  -11.521 -9.809  1.000 13.091 0 98  VAL A CG2 1 ? 
ATOM   522  N N   . PHE A 1 99  ? 11.614  -11.215 -9.719  1.000 11.395 0 99  PHE A N   1 ? 
ATOM   523  C CA  . PHE A 1 99  ? 10.484  -11.203 -10.615 1.000 11.058 0 99  PHE A CA  1 ? 
ATOM   524  C C   . PHE A 1 99  ? 11.020  -10.889 -12.016 1.000 12.341 0 99  PHE A C   1 ? 
ATOM   525  O O   . PHE A 1 99  ? 11.854  -9.981  -12.177 1.000 12.340 0 99  PHE A O   1 ? 
ATOM   526  C CB  . PHE A 1 99  ? 9.502   -10.130 -10.197 1.000 11.616 0 99  PHE A CB  1 ? 
ATOM   527  C CG  . PHE A 1 99  ? 8.915   -10.391 -8.826  1.000 10.805 0 99  PHE A CG  1 ? 
ATOM   528  C CD1 . PHE A 1 99  ? 9.609   -10.013 -7.677  1.000 11.550 0 99  PHE A CD1 1 ? 
ATOM   529  C CD2 . PHE A 1 99  ? 7.684   -11.030 -8.703  1.000 10.864 0 99  PHE A CD2 1 ? 
ATOM   530  C CE1 . PHE A 1 99  ? 9.104   -10.310 -6.430  1.000 11.445 0 99  PHE A CE1 1 ? 
ATOM   531  C CE2 . PHE A 1 99  ? 7.187   -11.314 -7.444  1.000 10.945 0 99  PHE A CE2 1 ? 
ATOM   532  C CZ  . PHE A 1 99  ? 7.903   -10.982 -6.313  1.000 11.106 0 99  PHE A CZ  1 ? 
ATOM   533  N N   . VAL A 1 100 ? 10.440  -11.502 -13.057 1.000 11.301 0 100 VAL A N   1 ? 
ATOM   534  C CA  . VAL A 1 100 ? 10.809  -11.170 -14.433 1.000 11.744 0 100 VAL A CA  1 ? 
ATOM   535  C C   . VAL A 1 100 ? 9.677   -11.588 -15.340 1.000 11.242 0 100 VAL A C   1 ? 
ATOM   536  O O   . VAL A 1 100 ? 8.936   -12.541 -15.058 1.000 12.485 0 100 VAL A O   1 ? 
ATOM   537  C CB  . VAL A 1 100 ? 12.153  -11.821 -14.829 1.000 12.791 0 100 VAL A CB  1 ? 
ATOM   538  C CG1 . VAL A 1 100 ? 11.959  -13.291 -15.103 1.000 12.127 0 100 VAL A CG1 1 ? 
ATOM   539  C CG2 . VAL A 1 100 ? 12.840  -11.114 -15.981 1.000 12.974 0 100 VAL A CG2 1 ? 
ATOM   540  N N   . ARG A 1 101 ? 9.591   -10.941 -16.509 1.000 10.740 0 101 ARG A N   1 ? 
ATOM   541  C CA  . ARG A 1 101 ? 8.695   -11.457 -17.529 1.000 10.732 0 101 ARG A CA  1 ? 
ATOM   542  C C   . ARG A 1 101 ? 9.323   -12.651 -18.222 1.000 10.736 0 101 ARG A C   1 ? 
ATOM   543  O O   . ARG A 1 101 ? 10.526  -12.681 -18.459 1.000 11.940 0 101 ARG A O   1 ? 
ATOM   544  C CB  . ARG A 1 101 ? 8.417   -10.352 -18.546 1.000 12.113 0 101 ARG A CB  1 ? 
ATOM   545  C CG  . ARG A 1 101 ? 7.264   -10.702 -19.479 1.000 11.704 0 101 ARG A CG  1 ? 
ATOM   546  C CD  . ARG A 1 101 ? 6.848   -9.592  -20.436 1.000 12.023 0 101 ARG A CD  1 ? 
ATOM   547  N NE  . ARG A 1 101 ? 7.890   -9.295  -21.406 1.000 12.640 0 101 ARG A NE  1 ? 
ATOM   548  C CZ  . ARG A 1 101 ? 7.800   -8.343  -22.324 1.000 12.671 0 101 ARG A CZ  1 ? 
ATOM   549  N NH1 . ARG A 1 101 ? 6.674   -7.652  -22.431 1.000 13.491 0 101 ARG A NH1 1 ? 
ATOM   550  N NH2 . ARG A 1 101 ? 8.808   -8.123  -23.159 1.000 13.656 0 101 ARG A NH2 1 ? 
ATOM   551  N N   . GLY A 1 102 ? 8.509   -13.667 -18.514 1.000 11.899 0 102 GLY A N   1 ? 
ATOM   552  C CA  . GLY A 1 102 ? 8.974   -14.884 -19.169 1.000 12.820 0 102 GLY A CA  1 ? 
ATOM   553  C C   . GLY A 1 102 ? 8.754   -14.823 -20.668 1.000 12.127 0 102 GLY A C   1 ? 
ATOM   554  O O   . GLY A 1 102 ? 8.226   -13.856 -21.212 1.000 12.689 0 102 GLY A O   1 ? 
ATOM   555  N N   . THR A 1 103 ? 9.079   -15.931 -21.343 1.000 13.840 0 103 THR A N   1 ? 
ATOM   556  C CA  . THR A 1 103 ? 8.940   -15.948 -22.801 1.000 14.287 0 103 THR A CA  1 ? 
ATOM   557  C C   . THR A 1 103 ? 7.469   -16.046 -23.226 1.000 14.313 0 103 THR A C   1 ? 
ATOM   558  O O   . THR A 1 103 ? 7.157   -15.784 -24.384 1.000 17.360 0 103 THR A O   1 ? 
ATOM   559  C CB  . THR A 1 103 ? 9.741   -17.103 -23.407 1.000 17.888 0 103 THR A CB  1 ? 
ATOM   560  O OG1 . THR A 1 103 ? 9.250   -18.296 -22.817 1.000 20.427 0 103 THR A OG1 1 ? 
ATOM   561  C CG2 . THR A 1 103 ? 11.236  -16.977 -23.194 1.000 19.145 0 103 THR A CG2 1 ? 
ATOM   562  N N   . ASP A 1 104 ? 6.575   -16.386 -22.294 1.000 13.820 0 104 ASP A N   1 ? 
ATOM   563  C CA  . ASP A 1 104 ? 5.144   -16.335 -22.502 1.000 13.570 0 104 ASP A CA  1 ? 
ATOM   564  C C   . ASP A 1 104 ? 4.499   -14.980 -22.227 1.000 11.932 0 104 ASP A C   1 ? 
ATOM   565  O O   . ASP A 1 104 ? 3.279   -14.844 -22.339 1.000 13.645 0 104 ASP A O   1 ? 
ATOM   566  C CB  . ASP A 1 104 ? 4.439   -17.422 -21.671 1.000 12.755 0 104 ASP A CB  1 ? 
ATOM   567  C CG  . ASP A 1 104 ? 4.647   -17.343 -20.167 1.000 13.455 0 104 ASP A CG  1 ? 
ATOM   568  O OD1 . ASP A 1 104 ? 5.452   -16.466 -19.726 1.000 14.177 0 104 ASP A OD1 1 ? 
ATOM   569  O OD2 . ASP A 1 104 ? 3.989   -18.109 -19.473 1.000 15.287 0 104 ASP A OD2 1 ? 
ATOM   570  N N   . ASN A 1 105 ? 5.319   -13.978 -21.851 1.000 12.760 0 105 ASN A N   1 ? 
ATOM   571  C CA  . ASN A 1 105 ? 4.905   -12.637 -21.455 1.000 13.045 0 105 ASN A CA  1 ? 
ATOM   572  C C   . ASN A 1 105 ? 4.144   -12.590 -20.128 1.000 12.501 0 105 ASN A C   1 ? 
ATOM   573  O O   . ASN A 1 105 ? 3.613   -11.546 -19.773 1.000 13.001 0 105 ASN A O   1 ? 
ATOM   574  C CB  . ASN A 1 105 ? 4.200   -11.880 -22.573 1.000 14.616 0 105 ASN A CB  1 ? 
ATOM   575  C CG  . ASN A 1 105 ? 5.150   -11.548 -23.685 1.000 17.141 0 105 ASN A CG  1 ? 
ATOM   576  O OD1 . ASN A 1 105 ? 6.296   -11.191 -23.445 1.000 17.668 0 105 ASN A OD1 1 ? 
ATOM   577  N ND2 . ASN A 1 105 ? 4.724   -11.836 -24.905 1.000 22.101 0 105 ASN A ND2 1 ? 
ATOM   578  N N   . ALA A 1 106 ? 4.097   -13.693 -19.393 1.000 11.636 0 106 ALA A N   1 ? 
ATOM   579  C CA  . ALA A 1 106 ? 3.613   -13.715 -18.028 1.000 11.572 0 106 ALA A CA  1 ? 
ATOM   580  C C   . ALA A 1 106 ? 4.672   -13.192 -17.073 1.000 11.828 0 106 ALA A C   1 ? 
ATOM   581  O O   . ALA A 1 106 ? 5.847   -13.175 -17.412 1.000 12.617 0 106 ALA A O   1 ? 
ATOM   582  C CB  . ALA A 1 106 ? 3.178   -15.087 -17.623 1.000 11.955 0 106 ALA A CB  1 ? 
ATOM   583  N N   . LEU A 1 107 ? 4.230   -12.857 -15.836 1.000 11.170 0 107 LEU A N   1 ? 
ATOM   584  C CA  . LEU A 1 107 ? 5.132   -12.566 -14.734 1.000 11.993 0 107 LEU A CA  1 ? 
ATOM   585  C C   . LEU A 1 107 ? 5.547   -13.860 -14.063 1.000 11.828 0 107 LEU A C   1 ? 
ATOM   586  O O   . LEU A 1 107 ? 4.694   -14.676 -13.725 1.000 12.775 0 107 LEU A O   1 ? 
ATOM   587  C CB  . LEU A 1 107 ? 4.417   -11.644 -13.750 1.000 11.219 0 107 LEU A CB  1 ? 
ATOM   588  C CG  . LEU A 1 107 ? 5.229   -11.251 -12.517 1.000 12.599 0 107 LEU A CG  1 ? 
ATOM   589  C CD1 . LEU A 1 107 ? 6.443   -10.404 -12.881 1.000 13.338 0 107 LEU A CD1 1 ? 
ATOM   590  C CD2 . LEU A 1 107 ? 4.386   -10.547 -11.490 1.000 13.126 0 107 LEU A CD2 1 ? 
ATOM   591  N N   . TRP A 1 108 ? 6.850   -14.054 -13.881 1.000 11.246 0 108 TRP A N   1 ? 
ATOM   592  C CA  . TRP A 1 108 ? 7.403   -15.191 -13.180 1.000 11.302 0 108 TRP A CA  1 ? 
ATOM   593  C C   . TRP A 1 108 ? 8.176   -14.755 -11.951 1.000 12.381 0 108 TRP A C   1 ? 
ATOM   594  O O   . TRP A 1 108 ? 8.689   -13.620 -11.885 1.000 10.922 0 108 TRP A O   1 ? 
ATOM   595  C CB  . TRP A 1 108 ? 8.303   -16.040 -14.091 1.000 11.654 0 108 TRP A CB  1 ? 
ATOM   596  C CG  . TRP A 1 108 ? 7.545   -16.751 -15.177 1.000 12.077 0 108 TRP A CG  1 ? 
ATOM   597  C CD1 . TRP A 1 108 ? 7.075   -16.169 -16.318 1.000 13.141 0 108 TRP A CD1 1 ? 
ATOM   598  C CD2 . TRP A 1 108 ? 7.201   -18.162 -15.242 1.000 13.191 0 108 TRP A CD2 1 ? 
ATOM   599  N NE1 . TRP A 1 108 ? 6.416   -17.109 -17.078 1.000 14.116 0 108 TRP A NE1 1 ? 
ATOM   600  C CE2 . TRP A 1 108 ? 6.511   -18.329 -16.469 1.000 14.003 0 108 TRP A CE2 1 ? 
ATOM   601  C CE3 . TRP A 1 108 ? 7.431   -19.263 -14.416 1.000 13.384 0 108 TRP A CE3 1 ? 
ATOM   602  C CZ2 . TRP A 1 108 ? 6.023   -19.569 -16.861 1.000 15.764 0 108 TRP A CZ2 1 ? 
ATOM   603  C CZ3 . TRP A 1 108 ? 6.962   -20.496 -14.807 1.000 15.702 0 108 TRP A CZ3 1 ? 
ATOM   604  C CH2 . TRP A 1 108 ? 6.281   -20.641 -16.032 1.000 14.471 0 108 TRP A CH2 1 ? 
ATOM   605  N N   . HIS A 1 109 ? 8.304   -15.637 -10.953 1.000 11.569 0 109 HIS A N   1 ? 
ATOM   606  C CA  . HIS A 1 109 ? 9.100   -15.294 -9.789  1.000 11.452 0 109 HIS A CA  1 ? 
ATOM   607  C C   . HIS A 1 109 ? 9.802   -16.531 -9.222  1.000 12.417 0 109 HIS A C   1 ? 
ATOM   608  O O   . HIS A 1 109 ? 9.458   -17.672 -9.552  1.000 12.453 0 109 HIS A O   1 ? 
ATOM   609  C CB  . HIS A 1 109 ? 8.292   -14.566 -8.738  1.000 12.156 0 109 HIS A CB  1 ? 
ATOM   610  C CG  . HIS A 1 109 ? 7.190   -15.352 -8.108  1.000 12.627 0 109 HIS A CG  1 ? 
ATOM   611  N ND1 . HIS A 1 109 ? 6.878   -15.096 -6.779  1.000 12.636 0 109 HIS A ND1 1 ? 
ATOM   612  C CD2 . HIS A 1 109 ? 6.317   -16.263 -8.551  1.000 14.763 0 109 HIS A CD2 1 ? 
ATOM   613  C CE1 . HIS A 1 109 ? 5.835   -15.858 -6.447  1.000 14.386 0 109 HIS A CE1 1 ? 
ATOM   614  N NE2 . HIS A 1 109 ? 5.477   -16.594 -7.490  1.000 14.041 0 109 HIS A NE2 1 ? 
ATOM   615  N N   . ASN A 1 110 ? 10.835  -16.269 -8.425  1.000 11.692 0 110 ASN A N   1 ? 
ATOM   616  C CA  . ASN A 1 110 ? 11.744  -17.255 -7.868  1.000 12.835 0 110 ASN A CA  1 ? 
ATOM   617  C C   . ASN A 1 110 ? 12.199  -16.662 -6.535  1.000 14.180 0 110 ASN A C   1 ? 
ATOM   618  O O   . ASN A 1 110 ? 12.416  -15.450 -6.440  1.000 14.788 0 110 ASN A O   1 ? 
ATOM   619  C CB  . ASN A 1 110 ? 12.882  -17.501 -8.862  1.000 13.628 0 110 ASN A CB  1 ? 
ATOM   620  C CG  . ASN A 1 110 ? 13.714  -18.742 -8.637  1.000 14.885 0 110 ASN A CG  1 ? 
ATOM   621  O OD1 . ASN A 1 110 ? 13.750  -19.281 -7.548  1.000 17.158 0 110 ASN A OD1 1 ? 
ATOM   622  N ND2 . ASN A 1 110 ? 14.372  -19.131 -9.715  1.000 17.970 0 110 ASN A ND2 1 ? 
ATOM   623  N N   . TRP A 1 111 ? 12.319  -17.476 -5.500  1.000 13.160 0 111 TRP A N   1 ? 
ATOM   624  C CA  . TRP A 1 111 ? 12.635  -16.963 -4.176  1.000 13.616 0 111 TRP A CA  1 ? 
ATOM   625  C C   . TRP A 1 111 ? 13.654  -17.834 -3.456  1.000 13.780 0 111 TRP A C   1 ? 
ATOM   626  O O   . TRP A 1 111 ? 13.653  -19.064 -3.571  1.000 14.011 0 111 TRP A O   1 ? 
ATOM   627  C CB  . TRP A 1 111 ? 11.373  -16.777 -3.318  1.000 14.288 0 111 TRP A CB  1 ? 
ATOM   628  C CG  . TRP A 1 111 ? 10.492  -17.992 -3.198  1.000 14.309 0 111 TRP A CG  1 ? 
ATOM   629  C CD1 . TRP A 1 111 ? 10.509  -18.971 -2.258  1.000 15.589 0 111 TRP A CD1 1 ? 
ATOM   630  C CD2 . TRP A 1 111 ? 9.476   -18.372 -4.151  1.000 13.838 0 111 TRP A CD2 1 ? 
ATOM   631  N NE1 . TRP A 1 111 ? 9.557   -19.919 -2.531  1.000 15.704 0 111 TRP A NE1 1 ? 
ATOM   632  C CE2 . TRP A 1 111 ? 8.926   -19.599 -3.701  1.000 14.153 0 111 TRP A CE2 1 ? 
ATOM   633  C CE3 . TRP A 1 111 ? 9.015   -17.790 -5.344  1.000 15.596 0 111 TRP A CE3 1 ? 
ATOM   634  C CZ2 . TRP A 1 111 ? 7.928   -20.261 -4.394  1.000 15.616 0 111 TRP A CZ2 1 ? 
ATOM   635  C CZ3 . TRP A 1 111 ? 8.031   -18.446 -6.035  1.000 16.191 0 111 TRP A CZ3 1 ? 
ATOM   636  C CH2 . TRP A 1 111 ? 7.502   -19.658 -5.561  1.000 17.152 0 111 TRP A CH2 1 ? 
ATOM   637  N N   . GLN A 1 112 ? 14.441  -17.169 -2.608  1.000 13.312 0 112 GLN A N   1 ? 
ATOM   638  C CA  . GLN A 1 112 ? 15.189  -17.897 -1.578  1.000 13.548 0 112 GLN A CA  1 ? 
ATOM   639  C C   . GLN A 1 112 ? 14.208  -18.641 -0.670  1.000 14.245 0 112 GLN A C   1 ? 
ATOM   640  O O   . GLN A 1 112 ? 13.162  -18.128 -0.329  1.000 14.972 0 112 GLN A O   1 ? 
ATOM   641  C CB  . GLN A 1 112 ? 16.030  -16.893 -0.819  1.000 13.039 0 112 GLN A CB  1 ? 
ATOM   642  C CG  . GLN A 1 112 ? 17.215  -16.337 -1.573  1.000 13.858 0 112 GLN A CG  1 ? 
ATOM   643  C CD  . GLN A 1 112 ? 17.969  -15.279 -0.796  1.000 12.851 0 112 GLN A CD  1 ? 
ATOM   644  O OE1 . GLN A 1 112 ? 17.479  -14.738 0.193   1.000 12.893 0 112 GLN A OE1 1 ? 
ATOM   645  N NE2 . GLN A 1 112 ? 19.192  -14.960 -1.253  1.000 12.385 0 112 GLN A NE2 1 ? 
ATOM   646  N N   . THR A 1 113 ? 14.541  -19.879 -0.289  1.000 15.780 0 113 THR A N   1 ? 
ATOM   647  C CA  . THR A 1 113 ? 13.628  -20.608 0.579   1.000 17.190 0 113 THR A CA  1 ? 
ATOM   648  C C   . THR A 1 113 ? 14.032  -20.437 2.030   1.000 18.053 0 113 THR A C   1 ? 
ATOM   649  O O   . THR A 1 113 ? 13.219  -20.679 2.911   1.000 19.675 0 113 THR A O   1 ? 
ATOM   650  C CB  . THR A 1 113 ? 13.464  -22.077 0.164   1.000 18.475 0 113 THR A CB  1 ? 
ATOM   651  O OG1 . THR A 1 113 ? 14.763  -22.677 0.080   1.000 21.673 0 113 THR A OG1 1 ? 
ATOM   652  C CG2 . THR A 1 113 ? 12.762  -22.223 -1.171  1.000 19.857 0 113 THR A CG2 1 ? 
ATOM   653  N N   . VAL A 1 114 ? 15.281  -20.022 2.281   1.000 16.322 0 114 VAL A N   1 ? 
ATOM   654  C CA  . VAL A 1 114 ? 15.705  -19.524 3.572   1.000 18.024 0 114 VAL A CA  1 ? 
ATOM   655  C C   . VAL A 1 114 ? 16.545  -18.279 3.293   1.000 17.816 0 114 VAL A C   1 ? 
ATOM   656  O O   . VAL A 1 114 ? 17.038  -18.137 2.176   1.000 18.013 0 114 VAL A O   1 ? 
ATOM   657  C CB  . VAL A 1 114 ? 16.573  -20.542 4.359   1.000 22.285 0 114 VAL A CB  1 ? 
ATOM   658  C CG1 . VAL A 1 114 ? 15.838  -21.849 4.648   1.000 23.937 0 114 VAL A CG1 1 ? 
ATOM   659  C CG2 . VAL A 1 114 ? 17.884  -20.822 3.634   1.000 23.442 0 114 VAL A CG2 1 ? 
ATOM   660  N N   . PRO A 1 115 ? 16.625  -17.314 4.212   1.000 18.892 0 115 PRO A N   1 ? 
ATOM   661  C CA  . PRO A 1 115 ? 17.377  -16.086 3.966   1.000 18.613 0 115 PRO A CA  1 ? 
ATOM   662  C C   . PRO A 1 115 ? 18.791  -16.393 3.508   1.000 21.453 0 115 PRO A C   1 ? 
ATOM   663  O O   . PRO A 1 115 ? 19.537  -17.141 4.169   1.000 21.272 0 115 PRO A O   1 ? 
ATOM   664  C CB  . PRO A 1 115 ? 17.374  -15.374 5.321   1.000 19.900 0 115 PRO A CB  1 ? 
ATOM   665  C CG  . PRO A 1 115 ? 16.099  -15.869 5.981   1.000 20.602 0 115 PRO A CG  1 ? 
ATOM   666  C CD  . PRO A 1 115 ? 15.975  -17.292 5.535   1.000 17.961 0 115 PRO A CD  1 ? 
ATOM   667  N N   . GLY A 1 116 ? 19.100  -15.888 2.305   1.000 18.489 0 116 GLY A N   1 ? 
ATOM   668  C CA  . GLY A 1 116 ? 20.434  -16.018 1.779   1.000 18.253 0 116 GLY A CA  1 ? 
ATOM   669  C C   . GLY A 1 116 ? 20.677  -17.227 0.879   1.000 18.958 0 116 GLY A C   1 ? 
ATOM   670  O O   . GLY A 1 116 ? 21.752  -17.293 0.282   1.000 21.823 0 116 GLY A O   1 ? 
ATOM   671  N N   . ALA A 1 117 ? 19.711  -18.174 0.698   1.000 18.125 0 117 ALA A N   1 ? 
ATOM   672  C CA  . ALA A 1 117 ? 20.011  -19.350 -0.100  1.000 19.509 0 117 ALA A CA  1 ? 
ATOM   673  C C   . ALA A 1 117 ? 18.786  -20.145 -0.524  1.000 19.175 0 117 ALA A C   1 ? 
ATOM   674  O O   . ALA A 1 117 ? 17.653  -19.893 -0.132  1.000 18.805 0 117 ALA A O   1 ? 
ATOM   675  C CB  . ALA A 1 117 ? 20.920  -20.268 0.679   1.000 21.794 0 117 ALA A CB  1 ? 
ATOM   676  N N   . GLY A 1 118 ? 19.066  -21.133 -1.353  1.000 18.702 0 118 GLY A N   1 ? 
ATOM   677  C CA  . GLY A 1 118 ? 18.093  -22.156 -1.686  1.000 19.018 0 118 GLY A CA  1 ? 
ATOM   678  C C   . GLY A 1 118 ? 16.942  -21.630 -2.530  1.000 19.129 0 118 GLY A C   1 ? 
ATOM   679  O O   . GLY A 1 118 ? 15.769  -21.743 -2.148  1.000 20.584 0 118 GLY A O   1 ? 
ATOM   680  N N   . TRP A 1 119 ? 17.238  -21.343 -3.794  1.000 17.146 0 119 TRP A N   1 ? 
ATOM   681  C CA  . TRP A 1 119 ? 16.200  -20.833 -4.668  1.000 15.594 0 119 TRP A CA  1 ? 
ATOM   682  C C   . TRP A 1 119 ? 15.130  -21.889 -4.983  1.000 17.149 0 119 TRP A C   1 ? 
ATOM   683  O O   . TRP A 1 119 ? 15.448  -23.049 -5.231  1.000 18.594 0 119 TRP A O   1 ? 
ATOM   684  C CB  . TRP A 1 119 ? 16.802  -20.207 -5.921  1.000 15.356 0 119 TRP A CB  1 ? 
ATOM   685  C CG  . TRP A 1 119 ? 17.590  -18.970 -5.584  1.000 14.297 0 119 TRP A CG  1 ? 
ATOM   686  C CD1 . TRP A 1 119 ? 18.889  -18.894 -5.175  1.000 15.058 0 119 TRP A CD1 1 ? 
ATOM   687  C CD2 . TRP A 1 119 ? 17.099  -17.619 -5.572  1.000 13.322 0 119 TRP A CD2 1 ? 
ATOM   688  N NE1 . TRP A 1 119 ? 19.210  -17.603 -4.865  1.000 15.032 0 119 TRP A NE1 1 ? 
ATOM   689  C CE2 . TRP A 1 119 ? 18.141  -16.798 -5.111  1.000 12.500 0 119 TRP A CE2 1 ? 
ATOM   690  C CE3 . TRP A 1 119 ? 15.864  -17.048 -5.885  1.000 13.806 0 119 TRP A CE3 1 ? 
ATOM   691  C CZ2 . TRP A 1 119 ? 18.000  -15.424 -4.995  1.000 12.351 0 119 TRP A CZ2 1 ? 
ATOM   692  C CZ3 . TRP A 1 119 ? 15.718  -15.690 -5.738  1.000 14.000 0 119 TRP A CZ3 1 ? 
ATOM   693  C CH2 . TRP A 1 119 ? 16.789  -14.896 -5.324  1.000 12.745 0 119 TRP A CH2 1 ? 
ATOM   694  N N   . SER A 1 120 ? 13.874  -21.437 -4.998  1.000 16.880 0 120 SER A N   1 ? 
ATOM   695  C CA  . SER A 1 120 ? 12.712  -22.295 -5.209  1.000 16.923 0 120 SER A CA  1 ? 
ATOM   696  C C   . SER A 1 120 ? 12.661  -22.885 -6.609  1.000 16.522 0 120 SER A C   1 ? 
ATOM   697  O O   . SER A 1 120 ? 12.090  -23.972 -6.789  1.000 19.123 0 120 SER A O   1 ? 
ATOM   698  C CB  . SER A 1 120 ? 11.432  -21.501 -4.975  1.000 18.136 0 120 SER A CB  1 ? 
ATOM   699  O OG  . SER A 1 120 ? 11.414  -20.347 -5.835  1.000 16.613 0 120 SER A OG  1 ? 
ATOM   700  N N   . GLY A 1 121 ? 13.179  -22.163 -7.586  1.000 16.890 0 121 GLY A N   1 ? 
ATOM   701  C CA  . GLY A 1 121 ? 12.873  -22.384 -8.992  1.000 15.353 0 121 GLY A CA  1 ? 
ATOM   702  C C   . GLY A 1 121 ? 11.704  -21.451 -9.381  1.000 14.790 0 121 GLY A C   1 ? 
ATOM   703  O O   . GLY A 1 121 ? 10.998  -20.949 -8.518  1.000 17.847 0 121 GLY A O   1 ? 
ATOM   704  N N   . TRP A 1 122 ? 11.500  -21.290 -10.673 1.000 16.908 0 122 TRP A N   1 ? 
ATOM   705  C CA  . TRP A 1 122 ? 10.558  -20.314 -11.183 1.000 16.661 0 122 TRP A CA  1 ? 
ATOM   706  C C   . TRP A 1 122 ? 9.122   -20.830 -11.164 1.000 16.987 0 122 TRP A C   1 ? 
ATOM   707  O O   . TRP A 1 122 ? 8.855   -21.968 -11.572 1.000 19.608 0 122 TRP A O   1 ? 
ATOM   708  C CB  . TRP A 1 122 ? 10.935  -19.960 -12.611 1.000 16.473 0 122 TRP A CB  1 ? 
ATOM   709  C CG  . TRP A 1 122 ? 12.229  -19.203 -12.707 1.000 17.643 0 122 TRP A CG  1 ? 
ATOM   710  C CD1 . TRP A 1 122 ? 13.459  -19.724 -13.015 1.000 22.529 0 122 TRP A CD1 1 ? 
ATOM   711  C CD2 . TRP A 1 122 ? 12.428  -17.795 -12.486 1.000 18.023 0 122 TRP A CD2 1 ? 
ATOM   712  N NE1 . TRP A 1 122 ? 14.401  -18.720 -13.019 1.000 24.049 0 122 TRP A NE1 1 ? 
ATOM   713  C CE2 . TRP A 1 122 ? 13.803  -17.529 -12.693 1.000 18.760 0 122 TRP A CE2 1 ? 
ATOM   714  C CE3 . TRP A 1 122 ? 11.588  -16.737 -12.148 1.000 14.130 0 122 TRP A CE3 1 ? 
ATOM   715  C CZ2 . TRP A 1 122 ? 14.337  -16.256 -12.537 1.000 18.456 0 122 TRP A CZ2 1 ? 
ATOM   716  C CZ3 . TRP A 1 122 ? 12.113  -15.469 -12.048 1.000 14.818 0 122 TRP A CZ3 1 ? 
ATOM   717  C CH2 . TRP A 1 122 ? 13.482  -15.228 -12.249 1.000 14.525 0 122 TRP A CH2 1 ? 
ATOM   718  N N   . GLN A 1 123 ? 8.204   -19.941 -10.763 1.000 15.904 0 123 GLN A N   1 ? 
ATOM   719  C CA  . GLN A 1 123 ? 6.776   -20.208 -10.809 1.000 15.323 0 123 GLN A CA  1 ? 
ATOM   720  C C   . GLN A 1 123 ? 6.053   -19.032 -11.408 1.000 13.066 0 123 GLN A C   1 ? 
ATOM   721  O O   . GLN A 1 123 ? 6.456   -17.872 -11.270 1.000 12.971 0 123 GLN A O   1 ? 
ATOM   722  C CB  . GLN A 1 123 ? 6.294   -20.519 -9.402  1.000 17.663 0 123 GLN A CB  1 ? 
ATOM   723  C CG  . GLN A 1 123 ? 6.974   -21.807 -8.976  1.000 26.112 0 123 GLN A CG  1 ? 
ATOM   724  C CD  . GLN A 1 123 ? 6.387   -22.469 -7.759  1.000 32.811 0 123 GLN A CD  1 ? 
ATOM   725  O OE1 . GLN A 1 123 ? 5.212   -22.309 -7.450  1.000 37.202 0 123 GLN A OE1 1 ? 
ATOM   726  N NE2 . GLN A 1 123 ? 7.225   -23.241 -7.078  1.000 37.328 0 123 GLN A NE2 1 ? 
ATOM   727  N N   . SER A 1 124 ? 4.965   -19.335 -12.115 1.000 12.793 0 124 SER A N   1 ? 
ATOM   728  C CA  . SER A 1 124 ? 4.224   -18.316 -12.830 1.000 12.459 0 124 SER A CA  1 ? 
ATOM   729  C C   . SER A 1 124 ? 3.234   -17.590 -11.946 1.000 12.961 0 124 SER A C   1 ? 
ATOM   730  O O   . SER A 1 124 ? 2.514   -18.211 -11.155 1.000 15.441 0 124 SER A O   1 ? 
ATOM   731  C CB  . SER A 1 124 ? 3.498   -18.918 -14.005 1.000 13.703 0 124 SER A CB  1 ? 
ATOM   732  O OG  . SER A 1 124 ? 2.785   -17.932 -14.714 1.000 15.440 0 124 SER A OG  1 ? 
ATOM   733  N N   . LEU A 1 125 ? 3.166   -16.261 -12.121 1.000 12.063 0 125 LEU A N   1 ? 
ATOM   734  C CA  . LEU A 1 125 ? 2.072   -15.458 -11.587 1.000 12.142 0 125 LEU A CA  1 ? 
ATOM   735  C C   . LEU A 1 125 ? 1.130   -15.010 -12.691 1.000 11.982 0 125 LEU A C   1 ? 
ATOM   736  O O   . LEU A 1 125 ? 0.224   -14.206 -12.446 1.000 13.675 0 125 LEU A O   1 ? 
ATOM   737  C CB  . LEU A 1 125 ? 2.651   -14.250 -10.857 1.000 12.817 0 125 LEU A CB  1 ? 
ATOM   738  C CG  . LEU A 1 125 ? 3.272   -14.560 -9.496  1.000 13.852 0 125 LEU A CG  1 ? 
ATOM   739  C CD1 . LEU A 1 125 ? 4.041   -13.345 -8.999  1.000 15.168 0 125 LEU A CD1 1 ? 
ATOM   740  C CD2 . LEU A 1 125 ? 2.241   -14.994 -8.490  1.000 16.847 0 125 LEU A CD2 1 ? 
ATOM   741  N N   . GLY A 1 126 ? 1.282   -15.585 -13.894 1.000 13.374 0 126 GLY A N   1 ? 
ATOM   742  C CA  . GLY A 1 126 ? 0.360   -15.344 -14.978 1.000 12.986 0 126 GLY A CA  1 ? 
ATOM   743  C C   . GLY A 1 126 ? 0.343   -13.910 -15.475 1.000 13.046 0 126 GLY A C   1 ? 
ATOM   744  O O   . GLY A 1 126 ? 1.320   -13.160 -15.370 1.000 12.009 0 126 GLY A O   1 ? 
ATOM   745  N N   . GLY A 1 127 ? -0.814  -13.533 -16.018 1.000 14.724 0 127 GLY A N   1 ? 
ATOM   746  C CA  . GLY A 1 127 ? -0.942  -12.216 -16.609 1.000 13.971 0 127 GLY A CA  1 ? 
ATOM   747  C C   . GLY A 1 127 ? -0.245  -12.098 -17.966 1.000 13.601 0 127 GLY A C   1 ? 
ATOM   748  O O   . GLY A 1 127 ? 0.418   -13.035 -18.435 1.000 14.294 0 127 GLY A O   1 ? 
ATOM   749  N N   . GLN A 1 128 ? -0.411  -10.904 -18.571 1.000 14.106 0 128 GLN A N   1 ? 
ATOM   750  C CA  . GLN A 1 128 ? 0.412   -10.494 -19.690 1.000 14.737 0 128 GLN A CA  1 ? 
ATOM   751  C C   . GLN A 1 128 ? 0.947   -9.130  -19.320 1.000 15.325 0 128 GLN A C   1 ? 
ATOM   752  O O   . GLN A 1 128 ? 0.138   -8.238  -19.021 1.000 16.866 0 128 GLN A O   1 ? 
ATOM   753  C CB  . GLN A 1 128 ? -0.396  -10.442 -20.979 1.000 16.231 0 128 GLN A CB  1 ? 
ATOM   754  C CG  . GLN A 1 128 ? -0.894  -11.818 -21.468 1.000 16.377 0 128 GLN A CG  1 ? 
ATOM   755  C CD  . GLN A 1 128 ? 0.243   -12.558 -22.117 1.000 18.180 0 128 GLN A CD  1 ? 
ATOM   756  O OE1 . GLN A 1 128 ? 0.490   -12.396 -23.315 1.000 22.596 0 128 GLN A OE1 1 ? 
ATOM   757  N NE2 . GLN A 1 128 ? 0.941   -13.389 -21.353 1.000 15.189 0 128 GLN A NE2 1 ? 
ATOM   758  N N   . ILE A 1 129 ? 2.264   -8.966  -19.301 1.000 13.815 0 129 ILE A N   1 ? 
ATOM   759  C CA  . ILE A 1 129 ? 2.776   -7.654  -18.951 1.000 14.479 0 129 ILE A CA  1 ? 
ATOM   760  C C   . ILE A 1 129 ? 3.593   -7.101  -20.111 1.000 13.966 0 129 ILE A C   1 ? 
ATOM   761  O O   . ILE A 1 129 ? 4.193   -7.870  -20.907 1.000 13.472 0 129 ILE A O   1 ? 
ATOM   762  C CB  . ILE A 1 129 ? 3.528   -7.647  -17.600 1.000 14.877 0 129 ILE A CB  1 ? 
ATOM   763  C CG1 . ILE A 1 129 ? 4.775   -8.523  -17.622 1.000 16.566 0 129 ILE A CG1 1 ? 
ATOM   764  C CG2 . ILE A 1 129 ? 2.606   -8.061  -16.446 1.000 16.121 0 129 ILE A CG2 1 ? 
ATOM   765  C CD1 . ILE A 1 129 ? 5.703   -8.365  -16.427 1.000 18.048 0 129 ILE A CD1 1 ? 
ATOM   766  N N   . THR A 1 130 ? 3.584   -5.749  -20.197 1.000 12.764 0 130 THR A N   1 ? 
ATOM   767  C CA  . THR A 1 130 ? 4.158   -5.044  -21.331 1.000 12.843 0 130 THR A CA  1 ? 
ATOM   768  C C   . THR A 1 130 ? 5.108   -3.955  -20.846 1.000 12.870 0 130 THR A C   1 ? 
ATOM   769  O O   . THR A 1 130 ? 5.548   -3.134  -21.621 1.000 14.944 0 130 THR A O   1 ? 
ATOM   770  C CB  . THR A 1 130 ? 3.047   -4.449  -22.203 1.000 13.771 0 130 THR A CB  1 ? 
ATOM   771  O OG1 . THR A 1 130 ? 2.355   -3.483  -21.403 1.000 14.073 0 130 THR A OG1 1 ? 
ATOM   772  C CG2 . THR A 1 130 ? 2.110   -5.519  -22.734 1.000 14.367 0 130 THR A CG2 1 ? 
ATOM   773  N N   . SER A 1 131 ? 5.463   -3.987  -19.561 1.000 11.803 0 131 SER A N   1 ? 
ATOM   774  C CA  . SER A 1 131 ? 6.545   -3.145  -19.031 1.000 11.979 0 131 SER A CA  1 ? 
ATOM   775  C C   . SER A 1 131 ? 7.408   -4.052  -18.177 1.000 12.230 0 131 SER A C   1 ? 
ATOM   776  O O   . SER A 1 131 ? 7.037   -5.193  -17.907 1.000 12.828 0 131 SER A O   1 ? 
ATOM   777  C CB  . SER A 1 131 ? 6.024   -1.967  -18.237 1.000 12.337 0 131 SER A CB  1 ? 
ATOM   778  O OG  . SER A 1 131 ? 5.588   -2.364  -16.953 1.000 12.812 0 131 SER A OG  1 ? 
ATOM   779  N N   . ASN A 1 132 ? 8.518   -3.488  -17.698 1.000 11.843 0 132 ASN A N   1 ? 
ATOM   780  C CA  . ASN A 1 132 ? 9.249   -4.157  -16.653 1.000 11.932 0 132 ASN A CA  1 ? 
ATOM   781  C C   . ASN A 1 132 ? 8.407   -4.132  -15.371 1.000 12.990 0 132 ASN A C   1 ? 
ATOM   782  O O   . ASN A 1 132 ? 7.628   -3.203  -15.159 1.000 13.728 0 132 ASN A O   1 ? 
ATOM   783  C CB  . ASN A 1 132 ? 10.598  -3.498  -16.418 1.000 11.898 0 132 ASN A CB  1 ? 
ATOM   784  C CG  . ASN A 1 132 ? 11.438  -3.452  -17.672 1.000 11.956 0 132 ASN A CG  1 ? 
ATOM   785  O OD1 . ASN A 1 132 ? 11.671  -4.495  -18.273 1.000 11.637 0 132 ASN A OD1 1 ? 
ATOM   786  N ND2 . ASN A 1 132 ? 11.837  -2.258  -18.076 1.000 13.532 0 132 ASN A ND2 1 ? 
ATOM   787  N N   . PRO A 1 133 ? 8.463   -5.198  -14.542 1.000 12.598 0 133 PRO A N   1 ? 
ATOM   788  C CA  . PRO A 1 133 ? 7.740   -5.229  -13.256 1.000 13.979 0 133 PRO A CA  1 ? 
ATOM   789  C C   . PRO A 1 133 ? 8.491   -4.460  -12.189 1.000 13.015 0 133 PRO A C   1 ? 
ATOM   790  O O   . PRO A 1 133 ? 9.730   -4.435  -12.220 1.000 13.232 0 133 PRO A O   1 ? 
ATOM   791  C CB  . PRO A 1 133 ? 7.762   -6.713  -12.894 1.000 15.214 0 133 PRO A CB  1 ? 
ATOM   792  C CG  . PRO A 1 133 ? 9.053   -7.249  -13.510 1.000 13.174 0 133 PRO A CG  1 ? 
ATOM   793  C CD  . PRO A 1 133 ? 9.205   -6.446  -14.790 1.000 13.376 0 133 PRO A CD  1 ? 
ATOM   794  N N   . VAL A 1 134 ? 7.747   -3.808  -11.283 1.000 12.190 0 134 VAL A N   1 ? 
ATOM   795  C CA  . VAL A 1 134 ? 8.360   -3.168  -10.120 1.000 12.777 0 134 VAL A CA  1 ? 
ATOM   796  C C   . VAL A 1 134 ? 7.672   -3.680  -8.876  1.000 11.661 0 134 VAL A C   1 ? 
ATOM   797  O O   . VAL A 1 134 ? 6.470   -3.969  -8.869  1.000 12.412 0 134 VAL A O   1 ? 
ATOM   798  C CB  . VAL A 1 134 ? 8.436   -1.613  -10.099 1.000 18.783 0 134 VAL A CB  1 ? 
ATOM   799  C CG1 . VAL A 1 134 ? 9.223   -1.062  -11.270 1.000 20.012 0 134 VAL A CG1 1 ? 
ATOM   800  C CG2 . VAL A 1 134 ? 7.084   -0.957  -10.024 1.000 20.629 0 134 VAL A CG2 1 ? 
ATOM   801  N N   . VAL A 1 135 ? 8.450   -3.748  -7.791  1.000 12.908 0 135 VAL A N   1 ? 
ATOM   802  C CA  . VAL A 1 135 ? 8.015   -4.406  -6.580  1.000 13.185 0 135 VAL A CA  1 ? 
ATOM   803  C C   . VAL A 1 135 ? 7.950   -3.412  -5.433  1.000 13.762 0 135 VAL A C   1 ? 
ATOM   804  O O   . VAL A 1 135 ? 8.831   -2.552  -5.283  1.000 16.626 0 135 VAL A O   1 ? 
ATOM   805  C CB  . VAL A 1 135 ? 8.945   -5.574  -6.175  1.000 15.118 0 135 VAL A CB  1 ? 
ATOM   806  C CG1 . VAL A 1 135 ? 8.318   -6.414  -5.074  1.000 16.119 0 135 VAL A CG1 1 ? 
ATOM   807  C CG2 . VAL A 1 135 ? 9.344   -6.419  -7.353  1.000 16.135 0 135 VAL A CG2 1 ? 
ATOM   808  N N   . TYR A 1 136 ? 6.925   -3.572  -4.620  1.000 14.487 0 136 TYR A N   1 ? 
ATOM   809  C CA  . TYR A 1 136 ? 6.654   -2.773  -3.451  1.000 13.431 0 136 TYR A CA  1 ? 
ATOM   810  C C   . TYR A 1 136 ? 6.491   -3.740  -2.295  1.000 14.309 0 136 TYR A C   1 ? 
ATOM   811  O O   . TYR A 1 136 ? 5.948   -4.817  -2.485  1.000 13.970 0 136 TYR A O   1 ? 
ATOM   812  C CB  . TYR A 1 136 ? 5.373   -1.961  -3.701  1.000 14.561 0 136 TYR A CB  1 ? 
ATOM   813  C CG  . TYR A 1 136 ? 4.890   -1.177  -2.491  1.000 13.790 0 136 TYR A CG  1 ? 
ATOM   814  C CD1 . TYR A 1 136 ? 5.567   -0.022  -2.095  1.000 13.585 0 136 TYR A CD1 1 ? 
ATOM   815  C CD2 . TYR A 1 136 ? 3.753   -1.545  -1.768  1.000 14.574 0 136 TYR A CD2 1 ? 
ATOM   816  C CE1 . TYR A 1 136 ? 5.135   0.710   -0.992  1.000 14.912 0 136 TYR A CE1 1 ? 
ATOM   817  C CE2 . TYR A 1 136 ? 3.330   -0.820  -0.657  1.000 13.479 0 136 TYR A CE2 1 ? 
ATOM   818  C CZ  . TYR A 1 136 ? 4.019   0.313   -0.281  1.000 14.960 0 136 TYR A CZ  1 ? 
ATOM   819  O OH  . TYR A 1 136 ? 3.636   1.006   0.831   1.000 17.373 0 136 TYR A OH  1 ? 
ATOM   820  N N   . ILE A 1 137 ? 6.808   -3.312  -1.062  1.000 15.493 0 137 ILE A N   1 ? 
ATOM   821  C CA  . ILE A 1 137 ? 6.394   -4.058  0.121   1.000 16.225 0 137 ILE A CA  1 ? 
ATOM   822  C C   . ILE A 1 137 ? 5.446   -3.206  0.957   1.000 15.261 0 137 ILE A C   1 ? 
ATOM   823  O O   . ILE A 1 137 ? 5.768   -2.088  1.297   1.000 16.060 0 137 ILE A O   1 ? 
ATOM   824  C CB  . ILE A 1 137 ? 7.583   -4.634  0.916   1.000 15.489 0 137 ILE A CB  1 ? 
ATOM   825  C CG1 . ILE A 1 137 ? 7.079   -5.730  1.866   1.000 16.950 0 137 ILE A CG1 1 ? 
ATOM   826  C CG2 . ILE A 1 137 ? 8.392   -3.568  1.657   1.000 15.600 0 137 ILE A CG2 1 ? 
ATOM   827  C CD1 . ILE A 1 137 ? 8.208   -6.538  2.546   1.000 17.895 0 137 ILE A CD1 1 ? 
ATOM   828  N N   . ASN A 1 138 ? 4.254   -3.748  1.240   1.000 14.913 0 138 ASN A N   1 ? 
ATOM   829  C CA  . ASN A 1 138 ? 3.269   -3.128  2.099   1.000 15.930 0 138 ASN A CA  1 ? 
ATOM   830  C C   . ASN A 1 138 ? 3.771   -3.077  3.540   1.000 17.875 0 138 ASN A C   1 ? 
ATOM   831  O O   . ASN A 1 138 ? 4.631   -3.845  3.927   1.000 17.405 0 138 ASN A O   1 ? 
ATOM   832  C CB  . ASN A 1 138 ? 1.954   -3.913  2.024   1.000 15.894 0 138 ASN A CB  1 ? 
ATOM   833  C CG  . ASN A 1 138 ? 1.255   -3.619  0.718   1.000 16.121 0 138 ASN A CG  1 ? 
ATOM   834  O OD1 . ASN A 1 138 ? 0.622   -2.575  0.563   1.000 17.422 0 138 ASN A OD1 1 ? 
ATOM   835  N ND2 . ASN A 1 138 ? 1.432   -4.490  -0.254  1.000 17.196 0 138 ASN A ND2 1 ? 
ATOM   836  N N   A SER A 1 139 ? 3.220   -2.153  4.326   0.500 18.759 0 139 SER A N   1 ? 
ATOM   837  N N   B SER A 1 139 ? 3.166   -2.184  4.321   0.500 19.638 0 139 SER A N   1 ? 
ATOM   838  C CA  A SER A 1 139 ? 3.625   -2.036  5.722   0.500 19.361 0 139 SER A CA  1 ? 
ATOM   839  C CA  B SER A 1 139 ? 3.530   -2.012  5.721   0.500 21.077 0 139 SER A CA  1 ? 
ATOM   840  C C   A SER A 1 139 ? 3.390   -3.331  6.503   0.500 20.575 0 139 SER A C   1 ? 
ATOM   841  C C   B SER A 1 139 ? 3.308   -3.276  6.548   0.500 21.645 0 139 SER A C   1 ? 
ATOM   842  O O   A SER A 1 139 ? 4.116   -3.608  7.456   0.500 21.168 0 139 SER A O   1 ? 
ATOM   843  O O   B SER A 1 139 ? 3.937   -3.457  7.585   0.500 24.435 0 139 SER A O   1 ? 
ATOM   844  C CB  A SER A 1 139 ? 2.939   -0.869  6.373   0.500 20.036 0 139 SER A CB  1 ? 
ATOM   845  C CB  B SER A 1 139 ? 2.777   -0.844  6.279   0.500 22.175 0 139 SER A CB  1 ? 
ATOM   846  O OG  A SER A 1 139 ? 1.539   -1.044  6.359   0.500 19.746 0 139 SER A OG  1 ? 
ATOM   847  O OG  B SER A 1 139 ? 3.224   0.336   5.635   0.500 24.520 0 139 SER A OG  1 ? 
ATOM   848  N N   . ASP A 1 140 ? 2.432   -4.161  6.098   1.000 19.391 0 140 ASP A N   1 ? 
ATOM   849  C CA  . ASP A 1 140 ? 2.181   -5.425  6.791   1.000 19.489 0 140 ASP A CA  1 ? 
ATOM   850  C C   . ASP A 1 140 ? 3.126   -6.548  6.359   1.000 18.779 0 140 ASP A C   1 ? 
ATOM   851  O O   . ASP A 1 140 ? 2.994   -7.681  6.831   1.000 21.657 0 140 ASP A O   1 ? 
ATOM   852  C CB  . ASP A 1 140 ? 0.715   -5.856  6.630   1.000 20.408 0 140 ASP A CB  1 ? 
ATOM   853  C CG  . ASP A 1 140 ? 0.281   -6.159  5.205   1.000 20.847 0 140 ASP A CG  1 ? 
ATOM   854  O OD1 . ASP A 1 140 ? 1.154   -6.087  4.278   1.000 19.191 0 140 ASP A OD1 1 ? 
ATOM   855  O OD2 . ASP A 1 140 ? -0.918  -6.492  5.031   1.000 23.938 0 140 ASP A OD2 1 ? 
ATOM   856  N N   . GLY A 1 141 ? 3.983   -6.293  5.366   1.000 16.955 0 141 GLY A N   1 ? 
ATOM   857  C CA  . GLY A 1 141 ? 4.908   -7.311  4.918   1.000 17.421 0 141 GLY A CA  1 ? 
ATOM   858  C C   . GLY A 1 141 ? 4.541   -8.056  3.628   1.000 17.269 0 141 GLY A C   1 ? 
ATOM   859  O O   . GLY A 1 141 ? 5.251   -9.008  3.274   1.000 19.586 0 141 GLY A O   1 ? 
ATOM   860  N N   . ARG A 1 142 ? 3.423   -7.707  2.991   1.000 14.804 0 142 ARG A N   1 ? 
ATOM   861  C CA  . ARG A 1 142 ? 3.035   -8.318  1.719   1.000 15.644 0 142 ARG A CA  1 ? 
ATOM   862  C C   . ARG A 1 142 ? 3.715   -7.632  0.542   1.000 15.045 0 142 ARG A C   1 ? 
ATOM   863  O O   . ARG A 1 142 ? 3.556   -6.429  0.323   1.000 14.308 0 142 ARG A O   1 ? 
ATOM   864  C CB  . ARG A 1 142 ? 1.511   -8.221  1.543   1.000 15.424 0 142 ARG A CB  1 ? 
ATOM   865  C CG  . ARG A 1 142 ? 0.720   -9.012  2.588   1.000 17.573 0 142 ARG A CG  1 ? 
ATOM   866  C CD  . ARG A 1 142 ? -0.774  -8.860  2.417   1.000 16.860 0 142 ARG A CD  1 ? 
ATOM   867  N NE  . ARG A 1 142 ? -1.185  -7.491  2.469   1.000 17.672 0 142 ARG A NE  1 ? 
ATOM   868  C CZ  . ARG A 1 142 ? -1.435  -6.746  1.400   1.000 18.962 0 142 ARG A CZ  1 ? 
ATOM   869  N NH1 . ARG A 1 142 ? -1.428  -7.311  0.203   1.000 20.355 0 142 ARG A NH1 1 ? 
ATOM   870  N NH2 . ARG A 1 142 ? -1.721  -5.463  1.521   1.000 23.815 0 142 ARG A NH2 1 ? 
ATOM   871  N N   . LEU A 1 143 ? 4.398   -8.433  -0.274  1.000 13.268 0 143 LEU A N   1 ? 
ATOM   872  C CA  . LEU A 1 143 ? 4.923   -7.933  -1.537  1.000 12.459 0 143 LEU A CA  1 ? 
ATOM   873  C C   . LEU A 1 143 ? 3.767   -7.683  -2.495  1.000 12.502 0 143 LEU A C   1 ? 
ATOM   874  O O   . LEU A 1 143 ? 2.731   -8.369  -2.457  1.000 12.409 0 143 LEU A O   1 ? 
ATOM   875  C CB  . LEU A 1 143 ? 5.885   -8.922  -2.179  1.000 12.285 0 143 LEU A CB  1 ? 
ATOM   876  C CG  . LEU A 1 143 ? 7.207   -9.211  -1.458  1.000 13.030 0 143 LEU A CG  1 ? 
ATOM   877  C CD1 . LEU A 1 143 ? 8.066   -10.147 -2.314  1.000 12.769 0 143 LEU A CD1 1 ? 
ATOM   878  C CD2 . LEU A 1 143 ? 7.971   -7.931  -1.170  1.000 13.799 0 143 LEU A CD2 1 ? 
ATOM   879  N N   . GLU A 1 144 ? 4.021   -6.762  -3.444  1.000 12.515 0 144 GLU A N   1 ? 
ATOM   880  C CA  . GLU A 1 144 ? 3.044   -6.358  -4.444  1.000 13.339 0 144 GLU A CA  1 ? 
ATOM   881  C C   . GLU A 1 144 ? 3.822   -5.910  -5.675  1.000 13.494 0 144 GLU A C   1 ? 
ATOM   882  O O   . GLU A 1 144 ? 4.834   -5.214  -5.568  1.000 14.953 0 144 GLU A O   1 ? 
ATOM   883  C CB  . GLU A 1 144 ? 2.137   -5.261  -3.868  1.000 12.731 0 144 GLU A CB  1 ? 
ATOM   884  C CG  . GLU A 1 144 ? 1.086   -4.682  -4.805  1.000 14.584 0 144 GLU A CG  1 ? 
ATOM   885  C CD  . GLU A 1 144 ? 0.055   -3.820  -4.098  1.000 17.956 0 144 GLU A CD  1 ? 
ATOM   886  O OE1 . GLU A 1 144 ? 0.258   -3.565  -2.894  1.000 24.929 0 144 GLU A OE1 1 ? 
ATOM   887  O OE2 . GLU A 1 144 ? -0.890  -3.344  -4.695  1.000 15.608 0 144 GLU A OE2 1 ? 
ATOM   888  N N   . VAL A 1 145 ? 3.377   -6.348  -6.827  1.000 11.465 0 145 VAL A N   1 ? 
ATOM   889  C CA  . VAL A 1 145 ? 4.024   -6.044  -8.086  1.000 11.264 0 145 VAL A CA  1 ? 
ATOM   890  C C   . VAL A 1 145 ? 3.097   -5.183  -8.930  1.000 12.320 0 145 VAL A C   1 ? 
ATOM   891  O O   . VAL A 1 145 ? 1.887   -5.454  -9.020  1.000 12.246 0 145 VAL A O   1 ? 
ATOM   892  C CB  . VAL A 1 145 ? 4.441   -7.335  -8.826  1.000 12.837 0 145 VAL A CB  1 ? 
ATOM   893  C CG1 . VAL A 1 145 ? 5.018   -7.027  -10.198 1.000 12.742 0 145 VAL A CG1 1 ? 
ATOM   894  C CG2 . VAL A 1 145 ? 5.411   -8.111  -7.984  1.000 12.704 0 145 VAL A CG2 1 ? 
ATOM   895  N N   . PHE A 1 146 ? 3.690   -4.172  -9.563  1.000 11.261 0 146 PHE A N   1 ? 
ATOM   896  C CA  . PHE A 1 146 ? 3.036   -3.289  -10.507 1.000 11.406 0 146 PHE A CA  1 ? 
ATOM   897  C C   . PHE A 1 146 ? 3.685   -3.444  -11.878 1.000 11.729 0 146 PHE A C   1 ? 
ATOM   898  O O   . PHE A 1 146 ? 4.899   -3.521  -11.997 1.000 12.510 0 146 PHE A O   1 ? 
ATOM   899  C CB  . PHE A 1 146 ? 3.196   -1.834  -10.021 1.000 10.633 0 146 PHE A CB  1 ? 
ATOM   900  C CG  . PHE A 1 146 ? 2.546   -1.557  -8.693  1.000 10.854 0 146 PHE A CG  1 ? 
ATOM   901  C CD1 . PHE A 1 146 ? 1.205   -1.171  -8.666  1.000 11.008 0 146 PHE A CD1 1 ? 
ATOM   902  C CD2 . PHE A 1 146 ? 3.214   -1.721  -7.494  1.000 11.882 0 146 PHE A CD2 1 ? 
ATOM   903  C CE1 . PHE A 1 146 ? 0.541   -1.010  -7.469  1.000 11.418 0 146 PHE A CE1 1 ? 
ATOM   904  C CE2 . PHE A 1 146 ? 2.562   -1.482  -6.302  1.000 12.865 0 146 PHE A CE2 1 ? 
ATOM   905  C CZ  . PHE A 1 146 ? 1.222   -1.147  -6.284  1.000 11.849 0 146 PHE A CZ  1 ? 
ATOM   906  N N   . ALA A 1 147 ? 2.867   -3.453  -12.926 1.000 11.241 0 147 ALA A N   1 ? 
ATOM   907  C CA  . ALA A 1 147 ? 3.337   -3.535  -14.301 1.000 12.391 0 147 ALA A CA  1 ? 
ATOM   908  C C   . ALA A 1 147 ? 2.275   -3.015  -15.230 1.000 12.230 0 147 ALA A C   1 ? 
ATOM   909  O O   . ALA A 1 147 ? 1.087   -3.134  -14.944 1.000 13.332 0 147 ALA A O   1 ? 
ATOM   910  C CB  . ALA A 1 147 ? 3.732   -4.944  -14.656 1.000 12.705 0 147 ALA A CB  1 ? 
ATOM   911  N N   . ARG A 1 148 ? 2.704   -2.576  -16.412 1.000 11.547 0 148 ARG A N   1 ? 
ATOM   912  C CA  . ARG A 1 148 ? 1.744   -2.289  -17.450 1.000 11.688 0 148 ARG A CA  1 ? 
ATOM   913  C C   . ARG A 1 148 ? 1.221   -3.581  -18.062 1.000 11.491 0 148 ARG A C   1 ? 
ATOM   914  O O   . ARG A 1 148 ? 1.951   -4.546  -18.200 1.000 11.453 0 148 ARG A O   1 ? 
ATOM   915  C CB  . ARG A 1 148 ? 2.395   -1.442  -18.530 1.000 12.958 0 148 ARG A CB  1 ? 
ATOM   916  C CG  . ARG A 1 148 ? 1.421   -0.869  -19.553 1.000 12.566 0 148 ARG A CG  1 ? 
ATOM   917  C CD  . ARG A 1 148 ? 2.088   0.006   -20.602 1.000 12.751 0 148 ARG A CD  1 ? 
ATOM   918  N NE  . ARG A 1 148 ? 3.032   -0.690  -21.461 1.000 14.065 0 148 ARG A NE  1 ? 
ATOM   919  C CZ  . ARG A 1 148 ? 3.667   -0.138  -22.478 1.000 16.825 0 148 ARG A CZ  1 ? 
ATOM   920  N NH1 . ARG A 1 148 ? 3.494   1.152   -22.747 1.000 16.502 0 148 ARG A NH1 1 ? 
ATOM   921  N NH2 . ARG A 1 148 ? 4.474   -0.888  -23.215 1.000 17.385 0 148 ARG A NH2 1 ? 
ATOM   922  N N   . GLY A 1 149 ? -0.063  -3.564  -18.427 1.000 12.546 0 149 GLY A N   1 ? 
ATOM   923  C CA  . GLY A 1 149 ? -0.769  -4.721  -18.966 1.000 11.533 0 149 GLY A CA  1 ? 
ATOM   924  C C   . GLY A 1 149 ? -0.848  -4.677  -20.487 1.000 12.953 0 149 GLY A C   1 ? 
ATOM   925  O O   . GLY A 1 149 ? -0.426  -3.709  -21.123 1.000 13.336 0 149 GLY A O   1 ? 
ATOM   926  N N   . ALA A 1 150 ? -1.531  -5.681  -21.037 1.000 15.264 0 150 ALA A N   1 ? 
ATOM   927  C CA  . ALA A 1 150 ? -1.734  -5.781  -22.474 1.000 15.214 0 150 ALA A CA  1 ? 
ATOM   928  C C   . ALA A 1 150 ? -2.651  -4.690  -23.030 1.000 16.835 0 150 ALA A C   1 ? 
ATOM   929  O O   . ALA A 1 150 ? -2.516  -4.358  -24.206 1.000 18.034 0 150 ALA A O   1 ? 
ATOM   930  C CB  . ALA A 1 150 ? -2.286  -7.153  -22.769 1.000 16.062 0 150 ALA A CB  1 ? 
ATOM   931  N N   . ASP A 1 151 ? -3.456  -4.069  -22.158 1.000 15.714 0 151 ASP A N   1 ? 
ATOM   932  C CA  . ASP A 1 151 ? -4.325  -2.971  -22.537 1.000 14.727 0 151 ASP A CA  1 ? 
ATOM   933  C C   . ASP A 1 151 ? -3.708  -1.606  -22.193 1.000 14.690 0 151 ASP A C   1 ? 
ATOM   934  O O   . ASP A 1 151 ? -4.406  -0.609  -22.240 1.000 15.668 0 151 ASP A O   1 ? 
ATOM   935  C CB  . ASP A 1 151 ? -5.683  -3.092  -21.859 1.000 16.167 0 151 ASP A CB  1 ? 
ATOM   936  C CG  . ASP A 1 151 ? -5.620  -3.109  -20.346 1.000 18.170 0 151 ASP A CG  1 ? 
ATOM   937  O OD1 . ASP A 1 151 ? -4.480  -2.993  -19.819 1.000 16.321 0 151 ASP A OD1 1 ? 
ATOM   938  O OD2 . ASP A 1 151 ? -6.669  -3.314  -19.720 1.000 17.691 0 151 ASP A OD2 1 ? 
ATOM   939  N N   . ASN A 1 152 ? -2.416  -1.612  -21.827 1.000 14.534 0 152 ASN A N   1 ? 
ATOM   940  C CA  . ASN A 1 152 ? -1.630  -0.439  -21.483 1.000 14.741 0 152 ASN A CA  1 ? 
ATOM   941  C C   . ASN A 1 152 ? -2.084  0.253   -20.212 1.000 14.191 0 152 ASN A C   1 ? 
ATOM   942  O O   . ASN A 1 152 ? -1.515  1.295   -19.876 1.000 13.962 0 152 ASN A O   1 ? 
ATOM   943  C CB  . ASN A 1 152 ? -1.480  0.571   -22.619 1.000 16.735 0 152 ASN A CB  1 ? 
ATOM   944  C CG  . ASN A 1 152 ? -0.654  0.004   -23.752 1.000 19.975 0 152 ASN A CG  1 ? 
ATOM   945  O OD1 . ASN A 1 152 ? 0.384   -0.611  -23.544 1.000 23.443 0 152 ASN A OD1 1 ? 
ATOM   946  N ND2 . ASN A 1 152 ? -1.141  0.173   -24.961 1.000 26.096 0 152 ASN A ND2 1 ? 
ATOM   947  N N   . ALA A 1 153 ? -2.976  -0.355  -19.446 1.000 12.365 0 153 ALA A N   1 ? 
ATOM   948  C CA  . ALA A 1 153 ? -3.305  0.082   -18.098 1.000 12.344 0 153 ALA A CA  1 ? 
ATOM   949  C C   . ALA A 1 153 ? -2.262  -0.402  -17.126 1.000 12.696 0 153 ALA A C   1 ? 
ATOM   950  O O   . ALA A 1 153 ? -1.453  -1.278  -17.422 1.000 12.435 0 153 ALA A O   1 ? 
ATOM   951  C CB  . ALA A 1 153 ? -4.651  -0.441  -17.672 1.000 13.171 0 153 ALA A CB  1 ? 
ATOM   952  N N   . LEU A 1 154 ? -2.312  0.194   -15.929 1.000 12.650 0 154 LEU A N   1 ? 
ATOM   953  C CA  . LEU A 1 154 ? -1.514  -0.287  -14.817 1.000 12.856 0 154 LEU A CA  1 ? 
ATOM   954  C C   . LEU A 1 154 ? -2.249  -1.456  -14.180 1.000 12.701 0 154 LEU A C   1 ? 
ATOM   955  O O   . LEU A 1 154 ? -3.407  -1.323  -13.808 1.000 12.845 0 154 LEU A O   1 ? 
ATOM   956  C CB  . LEU A 1 154 ? -1.334  0.822   -13.784 1.000 13.374 0 154 LEU A CB  1 ? 
ATOM   957  C CG  . LEU A 1 154 ? -0.572  0.428   -12.517 1.000 13.611 0 154 LEU A CG  1 ? 
ATOM   958  C CD1 . LEU A 1 154 ? 0.891   0.071   -12.828 1.000 13.772 0 154 LEU A CD1 1 ? 
ATOM   959  C CD2 . LEU A 1 154 ? -0.663  1.534   -11.444 1.000 14.969 0 154 LEU A CD2 1 ? 
ATOM   960  N N   . TRP A 1 155 ? -1.544  -2.555  -13.966 1.000 12.065 0 155 TRP A N   1 ? 
ATOM   961  C CA  . TRP A 1 155 ? -2.086  -3.678  -13.215 1.000 13.303 0 155 TRP A CA  1 ? 
ATOM   962  C C   . TRP A 1 155 ? -1.208  -3.971  -12.002 1.000 12.405 0 155 TRP A C   1 ? 
ATOM   963  O O   . TRP A 1 155 ? -0.016  -3.625  -11.981 1.000 11.847 0 155 TRP A O   1 ? 
ATOM   964  C CB  . TRP A 1 155 ? -2.229  -4.890  -14.140 1.000 14.349 0 155 TRP A CB  1 ? 
ATOM   965  C CG  . TRP A 1 155 ? -3.265  -4.729  -15.222 1.000 12.446 0 155 TRP A CG  1 ? 
ATOM   966  C CD1 . TRP A 1 155 ? -3.187  -3.972  -16.344 1.000 13.095 0 155 TRP A CD1 1 ? 
ATOM   967  C CD2 . TRP A 1 155 ? -4.513  -5.456  -15.304 1.000 12.969 0 155 TRP A CD2 1 ? 
ATOM   968  N NE1 . TRP A 1 155 ? -4.316  -4.135  -17.097 1.000 13.976 0 155 TRP A NE1 1 ? 
ATOM   969  C CE2 . TRP A 1 155 ? -5.116  -5.077  -16.532 1.000 12.491 0 155 TRP A CE2 1 ? 
ATOM   970  C CE3 . TRP A 1 155 ? -5.133  -6.421  -14.515 1.000 13.524 0 155 TRP A CE3 1 ? 
ATOM   971  C CZ2 . TRP A 1 155 ? -6.359  -5.573  -16.951 1.000 13.426 0 155 TRP A CZ2 1 ? 
ATOM   972  C CZ3 . TRP A 1 155 ? -6.341  -6.940  -14.938 1.000 14.004 0 155 TRP A CZ3 1 ? 
ATOM   973  C CH2 . TRP A 1 155 ? -6.940  -6.515  -16.136 1.000 14.405 0 155 TRP A CH2 1 ? 
ATOM   974  N N   . HIS A 1 156 ? -1.764  -4.707  -11.050 1.000 12.113 0 156 HIS A N   1 ? 
ATOM   975  C CA  . HIS A 1 156 ? -1.053  -5.117  -9.858  1.000 11.644 0 156 HIS A CA  1 ? 
ATOM   976  C C   . HIS A 1 156 ? -1.548  -6.455  -9.311  1.000 11.981 0 156 HIS A C   1 ? 
ATOM   977  O O   . HIS A 1 156 ? -2.658  -6.879  -9.604  1.000 12.386 0 156 HIS A O   1 ? 
ATOM   978  C CB  . HIS A 1 156 ? -1.024  -4.010  -8.793  1.000 12.264 0 156 HIS A CB  1 ? 
ATOM   979  C CG  . HIS A 1 156 ? -2.326  -3.713  -8.177  1.000 13.201 0 156 HIS A CG  1 ? 
ATOM   980  N ND1 . HIS A 1 156 ? -2.408  -3.416  -6.825  1.000 13.730 0 156 HIS A ND1 1 ? 
ATOM   981  C CD2 . HIS A 1 156 ? -3.572  -3.628  -8.672  1.000 13.713 0 156 HIS A CD2 1 ? 
ATOM   982  C CE1 . HIS A 1 156 ? -3.688  -3.165  -6.537  1.000 14.862 0 156 HIS A CE1 1 ? 
ATOM   983  N NE2 . HIS A 1 156 ? -4.421  -3.248  -7.644  1.000 14.533 0 156 HIS A NE2 1 ? 
ATOM   984  N N   . ILE A 1 157 ? -0.696  -7.064  -8.488  1.000 12.385 0 157 ILE A N   1 ? 
ATOM   985  C CA  . ILE A 1 157 ? -0.900  -8.407  -7.938  1.000 12.519 0 157 ILE A CA  1 ? 
ATOM   986  C C   . ILE A 1 157 ? -0.100  -8.449  -6.636  1.000 13.023 0 157 ILE A C   1 ? 
ATOM   987  O O   . ILE A 1 157 ? 0.925   -7.761  -6.573  1.000 12.196 0 157 ILE A O   1 ? 
ATOM   988  C CB  . ILE A 1 157 ? -0.458  -9.465  -8.977  1.000 13.516 0 157 ILE A CB  1 ? 
ATOM   989  C CG1 . ILE A 1 157 ? -0.958  -10.845 -8.563  1.000 14.239 0 157 ILE A CG1 1 ? 
ATOM   990  C CG2 . ILE A 1 157 ? 1.049   -9.476  -9.210  1.000 13.235 0 157 ILE A CG2 1 ? 
ATOM   991  C CD1 . ILE A 1 157 ? -0.773  -11.880 -9.639  1.000 14.458 0 157 ILE A CD1 1 ? 
ATOM   992  N N   . TRP A 1 158 ? -0.574  -9.146  -5.601  1.000 12.308 0 158 TRP A N   1 ? 
ATOM   993  C CA  . TRP A 1 158 ? 0.047   -9.074  -4.286  1.000 13.342 0 158 TRP A CA  1 ? 
ATOM   994  C C   . TRP A 1 158 ? -0.001  -10.435 -3.614  1.000 13.196 0 158 TRP A C   1 ? 
ATOM   995  O O   . TRP A 1 158 ? -0.906  -11.239 -3.814  1.000 12.565 0 158 TRP A O   1 ? 
ATOM   996  C CB  . TRP A 1 158 ? -0.592  -8.007  -3.385  1.000 13.538 0 158 TRP A CB  1 ? 
ATOM   997  C CG  . TRP A 1 158 ? -2.095  -8.089  -3.353  1.000 13.902 0 158 TRP A CG  1 ? 
ATOM   998  C CD1 . TRP A 1 158 ? -2.845  -8.765  -2.436  1.000 15.741 0 158 TRP A CD1 1 ? 
ATOM   999  C CD2 . TRP A 1 158 ? -3.015  -7.526  -4.296  1.000 14.228 0 158 TRP A CD2 1 ? 
ATOM   1000 N NE1 . TRP A 1 158 ? -4.176  -8.666  -2.741  1.000 15.863 0 158 TRP A NE1 1 ? 
ATOM   1001 C CE2 . TRP A 1 158 ? -4.314  -7.926  -3.882  1.000 15.731 0 158 TRP A CE2 1 ? 
ATOM   1002 C CE3 . TRP A 1 158 ? -2.856  -6.766  -5.466  1.000 14.814 0 158 TRP A CE3 1 ? 
ATOM   1003 C CZ2 . TRP A 1 158 ? -5.452  -7.566  -4.591  1.000 16.698 0 158 TRP A CZ2 1 ? 
ATOM   1004 C CZ3 . TRP A 1 158 ? -3.987  -6.418  -6.161  1.000 15.986 0 158 TRP A CZ3 1 ? 
ATOM   1005 C CH2 . TRP A 1 158 ? -5.257  -6.810  -5.722  1.000 16.199 0 158 TRP A CH2 1 ? 
ATOM   1006 N N   . GLN A 1 159 ? 0.944   -10.636 -2.702  1.000 12.742 0 159 GLN A N   1 ? 
ATOM   1007 C CA  . GLN A 1 159 ? 0.866   -11.662 -1.690  1.000 13.628 0 159 GLN A CA  1 ? 
ATOM   1008 C C   . GLN A 1 159 ? -0.381  -11.435 -0.837  1.000 13.565 0 159 GLN A C   1 ? 
ATOM   1009 O O   . GLN A 1 159 ? -0.671  -10.283 -0.451  1.000 14.055 0 159 GLN A O   1 ? 
ATOM   1010 C CB  . GLN A 1 159 ? 2.094   -11.602 -0.790  1.000 12.832 0 159 GLN A CB  1 ? 
ATOM   1011 C CG  . GLN A 1 159 ? 3.361   -12.131 -1.432  1.000 12.390 0 159 GLN A CG  1 ? 
ATOM   1012 C CD  . GLN A 1 159 ? 4.618   -11.977 -0.604  1.000 12.430 0 159 GLN A CD  1 ? 
ATOM   1013 O OE1 . GLN A 1 159 ? 4.678   -11.179 0.329   1.000 13.373 0 159 GLN A OE1 1 ? 
ATOM   1014 N NE2 . GLN A 1 159 ? 5.616   -12.778 -0.948  1.000 12.457 0 159 GLN A NE2 1 ? 
ATOM   1015 N N   . THR A 1 160 ? -1.087  -12.524 -0.513  1.000 14.712 0 160 THR A N   1 ? 
ATOM   1016 C CA  . THR A 1 160 ? -2.298  -12.318 0.284   1.000 16.621 0 160 THR A CA  1 ? 
ATOM   1017 C C   . THR A 1 160 ? -1.991  -12.378 1.779   1.000 17.461 0 160 THR A C   1 ? 
ATOM   1018 O O   . THR A 1 160 ? -2.859  -11.974 2.547   1.000 18.677 0 160 THR A O   1 ? 
ATOM   1019 C CB  . THR A 1 160 ? -3.426  -13.300 -0.077  1.000 16.058 0 160 THR A CB  1 ? 
ATOM   1020 O OG1 . THR A 1 160 ? -2.992  -14.634 0.126   1.000 18.453 0 160 THR A OG1 1 ? 
ATOM   1021 C CG2 . THR A 1 160 ? -3.825  -13.133 -1.524  1.000 19.111 0 160 THR A CG2 1 ? 
ATOM   1022 N N   . ALA A 1 161 ? -0.795  -12.817 2.177   1.000 16.841 0 161 ALA A N   1 ? 
ATOM   1023 C CA  . ALA A 1 161 ? -0.361  -12.845 3.555   1.000 16.560 0 161 ALA A CA  1 ? 
ATOM   1024 C C   . ALA A 1 161 ? 1.099   -12.415 3.599   1.000 17.133 0 161 ALA A C   1 ? 
ATOM   1025 O O   . ALA A 1 161 ? 1.804   -12.540 2.600   1.000 15.524 0 161 ALA A O   1 ? 
ATOM   1026 C CB  . ALA A 1 161 ? -0.531  -14.226 4.154   1.000 17.184 0 161 ALA A CB  1 ? 
ATOM   1027 N N   . PRO A 1 162 ? 1.574   -11.892 4.739   1.000 17.306 0 162 PRO A N   1 ? 
ATOM   1028 C CA  . PRO A 1 162 ? 2.954   -11.434 4.843   1.000 18.837 0 162 PRO A CA  1 ? 
ATOM   1029 C C   . PRO A 1 162 ? 3.904   -12.558 4.430   1.000 17.785 0 162 PRO A C   1 ? 
ATOM   1030 O O   . PRO A 1 162 ? 3.846   -13.694 4.919   1.000 18.505 0 162 PRO A O   1 ? 
ATOM   1031 C CB  . PRO A 1 162 ? 3.121   -11.024 6.307   1.000 21.192 0 162 PRO A CB  1 ? 
ATOM   1032 C CG  . PRO A 1 162 ? 1.713   -10.789 6.824   1.000 23.331 0 162 PRO A CG  1 ? 
ATOM   1033 C CD  . PRO A 1 162 ? 0.814   -11.666 5.979   1.000 20.124 0 162 PRO A CD  1 ? 
ATOM   1034 N N   . HIS A 1 163 ? 4.803   -12.228 3.482   1.000 17.873 0 163 HIS A N   1 ? 
ATOM   1035 C CA  . HIS A 1 163 ? 5.847   -13.114 2.997   1.000 17.390 0 163 HIS A CA  1 ? 
ATOM   1036 C C   . HIS A 1 163 ? 5.346   -14.510 2.645   1.000 17.625 0 163 HIS A C   1 ? 
ATOM   1037 O O   . HIS A 1 163 ? 6.073   -15.485 2.781   1.000 18.496 0 163 HIS A O   1 ? 
ATOM   1038 C CB  . HIS A 1 163 ? 7.044   -13.134 3.973   1.000 17.353 0 163 HIS A CB  1 ? 
ATOM   1039 C CG  . HIS A 1 163 ? 6.727   -13.554 5.366   1.000 18.618 0 163 HIS A CG  1 ? 
ATOM   1040 N ND1 . HIS A 1 163 ? 6.502   -14.865 5.693   1.000 19.083 0 163 HIS A ND1 1 ? 
ATOM   1041 C CD2 . HIS A 1 163 ? 6.653   -12.871 6.477   1.000 20.774 0 163 HIS A CD2 1 ? 
ATOM   1042 C CE1 . HIS A 1 163 ? 6.224   -14.916 7.003   1.000 17.911 0 163 HIS A CE1 1 ? 
ATOM   1043 N NE2 . HIS A 1 163 ? 6.310   -13.734 7.501   1.000 19.596 0 163 HIS A NE2 1 ? 
ATOM   1044 N N   . ALA A 1 164 ? 4.130   -14.626 2.077   1.000 16.693 0 164 ALA A N   1 ? 
ATOM   1045 C CA  . ALA A 1 164 ? 3.587   -15.945 1.780   1.000 16.848 0 164 ALA A CA  1 ? 
ATOM   1046 C C   . ALA A 1 164 ? 2.544   -15.849 0.680   1.000 16.663 0 164 ALA A C   1 ? 
ATOM   1047 O O   . ALA A 1 164 ? 1.766   -14.908 0.668   1.000 18.513 0 164 ALA A O   1 ? 
ATOM   1048 C CB  . ALA A 1 164 ? 2.982   -16.527 3.050   1.000 18.429 0 164 ALA A CB  1 ? 
ATOM   1049 N N   . GLY A 1 165 ? 2.554   -16.817 -0.234  1.000 17.355 0 165 GLY A N   1 ? 
ATOM   1050 C CA  . GLY A 1 165 ? 1.443   -17.110 -1.127  1.000 16.568 0 165 GLY A CA  1 ? 
ATOM   1051 C C   . GLY A 1 165 ? 0.235   -17.693 -0.394  1.000 19.939 0 165 GLY A C   1 ? 
ATOM   1052 O O   . GLY A 1 165 ? 0.247   -17.884 0.853   1.000 18.533 0 165 GLY A O   1 ? 
ATOM   1053 N N   . PRO A 1 166 ? -0.919  -17.771 -1.064  1.000 17.274 0 166 PRO A N   1 ? 
ATOM   1054 C CA  . PRO A 1 166 ? -1.051  -17.452 -2.477  1.000 16.854 0 166 PRO A CA  1 ? 
ATOM   1055 C C   . PRO A 1 166 ? -1.012  -15.952 -2.775  1.000 14.877 0 166 PRO A C   1 ? 
ATOM   1056 O O   . PRO A 1 166 ? -1.234  -15.084 -1.914  1.000 15.442 0 166 PRO A O   1 ? 
ATOM   1057 C CB  . PRO A 1 166 ? -2.455  -18.044 -2.751  1.000 16.112 0 166 PRO A CB  1 ? 
ATOM   1058 C CG  . PRO A 1 166 ? -3.239  -17.890 -1.489  1.000 17.899 0 166 PRO A CG  1 ? 
ATOM   1059 C CD  . PRO A 1 166 ? -2.213  -18.034 -0.404  1.000 17.484 0 166 PRO A CD  1 ? 
ATOM   1060 N N   . TRP A 1 167 ? -0.784  -15.672 -4.061  1.000 15.928 0 167 TRP A N   1 ? 
ATOM   1061 C CA  . TRP A 1 167 ? -0.953  -14.324 -4.579  1.000 14.719 0 167 TRP A CA  1 ? 
ATOM   1062 C C   . TRP A 1 167 ? -2.390  -14.140 -5.042  1.000 14.427 0 167 TRP A C   1 ? 
ATOM   1063 O O   . TRP A 1 167 ? -3.125  -15.104 -5.279  1.000 16.076 0 167 TRP A O   1 ? 
ATOM   1064 C CB  . TRP A 1 167 ? 0.022   -14.065 -5.731  1.000 13.312 0 167 TRP A CB  1 ? 
ATOM   1065 C CG  . TRP A 1 167 ? 1.449   -13.927 -5.266  1.000 13.171 0 167 TRP A CG  1 ? 
ATOM   1066 C CD1 . TRP A 1 167 ? 2.194   -14.853 -4.595  1.000 12.622 0 167 TRP A CD1 1 ? 
ATOM   1067 C CD2 . TRP A 1 167 ? 2.285   -12.763 -5.399  1.000 11.229 0 167 TRP A CD2 1 ? 
ATOM   1068 N NE1 . TRP A 1 167 ? 3.437   -14.362 -4.338  1.000 12.998 0 167 TRP A NE1 1 ? 
ATOM   1069 C CE2 . TRP A 1 167 ? 3.510   -13.069 -4.784  1.000 11.207 0 167 TRP A CE2 1 ? 
ATOM   1070 C CE3 . TRP A 1 167 ? 2.107   -11.488 -5.930  1.000 11.468 0 167 TRP A CE3 1 ? 
ATOM   1071 C CZ2 . TRP A 1 167 ? 4.569   -12.162 -4.728  1.000 11.746 0 167 TRP A CZ2 1 ? 
ATOM   1072 C CZ3 . TRP A 1 167 ? 3.152   -10.578 -5.878  1.000 11.829 0 167 TRP A CZ3 1 ? 
ATOM   1073 C CH2 . TRP A 1 167 ? 4.372   -10.924 -5.307  1.000 11.897 0 167 TRP A CH2 1 ? 
ATOM   1074 N N   . SER A 1 168 ? -2.798  -12.885 -5.120  1.000 14.489 0 168 SER A N   1 ? 
ATOM   1075 C CA  . SER A 1 168 ? -4.100  -12.449 -5.587  1.000 15.744 0 168 SER A CA  1 ? 
ATOM   1076 C C   . SER A 1 168 ? -4.208  -12.682 -7.089  1.000 14.743 0 168 SER A C   1 ? 
ATOM   1077 O O   . SER A 1 168 ? -3.226  -13.038 -7.762  1.000 15.085 0 168 SER A O   1 ? 
ATOM   1078 C CB  . SER A 1 168 ? -4.265  -10.971 -5.267  1.000 15.567 0 168 SER A CB  1 ? 
ATOM   1079 O OG  . SER A 1 168 ? -3.427  -10.195 -6.144  1.000 13.809 0 168 SER A OG  1 ? 
ATOM   1080 N N   . ASN A 1 169 ? -5.413  -12.464 -7.626  1.000 16.709 0 169 ASN A N   1 ? 
ATOM   1081 C CA  . ASN A 1 169 ? -5.571  -12.320 -9.055  1.000 19.013 0 169 ASN A CA  1 ? 
ATOM   1082 C C   . ASN A 1 169 ? -4.975  -10.971 -9.445  1.000 16.431 0 169 ASN A C   1 ? 
ATOM   1083 O O   . ASN A 1 169 ? -4.906  -10.076 -8.616  1.000 15.263 0 169 ASN A O   1 ? 
ATOM   1084 C CB  . ASN A 1 169 ? -7.050  -12.418 -9.441  1.000 25.258 0 169 ASN A CB  1 ? 
ATOM   1085 C CG  . ASN A 1 169 ? -7.615  -13.800 -9.173  1.000 35.259 0 169 ASN A CG  1 ? 
ATOM   1086 O OD1 . ASN A 1 169 ? -7.090  -14.779 -9.680  1.000 38.250 0 169 ASN A OD1 1 ? 
ATOM   1087 N ND2 . ASN A 1 169 ? -8.632  -13.905 -8.329  1.000 41.526 0 169 ASN A ND2 1 ? 
ATOM   1088 N N   . TRP A 1 170 ? -4.613  -10.816 -10.717 1.000 16.155 0 170 TRP A N   1 ? 
ATOM   1089 C CA  . TRP A 1 170 ? -4.308  -9.538  -11.310 1.000 14.145 0 170 TRP A CA  1 ? 
ATOM   1090 C C   . TRP A 1 170 ? -5.518  -8.616  -11.227 1.000 14.870 0 170 TRP A C   1 ? 
ATOM   1091 O O   . TRP A 1 170 ? -6.633  -9.056  -11.518 1.000 17.103 0 170 TRP A O   1 ? 
ATOM   1092 C CB  . TRP A 1 170 ? -3.878  -9.704  -12.765 1.000 15.008 0 170 TRP A CB  1 ? 
ATOM   1093 C CG  . TRP A 1 170 ? -2.469  -10.205 -12.908 1.000 13.538 0 170 TRP A CG  1 ? 
ATOM   1094 C CD1 . TRP A 1 170 ? -2.048  -11.477 -13.181 1.000 14.574 0 170 TRP A CD1 1 ? 
ATOM   1095 C CD2 . TRP A 1 170 ? -1.268  -9.411  -12.801 1.000 12.876 0 170 TRP A CD2 1 ? 
ATOM   1096 N NE1 . TRP A 1 170 ? -0.681  -11.525 -13.268 1.000 15.443 0 170 TRP A NE1 1 ? 
ATOM   1097 C CE2 . TRP A 1 170 ? -0.167  -10.283 -13.038 1.000 14.287 0 170 TRP A CE2 1 ? 
ATOM   1098 C CE3 . TRP A 1 170 ? -0.992  -8.065  -12.550 1.000 12.960 0 170 TRP A CE3 1 ? 
ATOM   1099 C CZ2 . TRP A 1 170 ? 1.144   -9.832  -13.046 1.000 13.725 0 170 TRP A CZ2 1 ? 
ATOM   1100 C CZ3 . TRP A 1 170 ? 0.306   -7.622  -12.557 1.000 12.161 0 170 TRP A CZ3 1 ? 
ATOM   1101 C CH2 . TRP A 1 170 ? 1.369   -8.504  -12.790 1.000 12.562 0 170 TRP A CH2 1 ? 
ATOM   1102 N N   . GLN A 1 171 ? -5.288  -7.353  -10.875 1.000 13.647 0 171 GLN A N   1 ? 
ATOM   1103 C CA  . GLN A 1 171 ? -6.348  -6.361  -10.878 1.000 14.206 0 171 GLN A CA  1 ? 
ATOM   1104 C C   . GLN A 1 171 ? -5.856  -5.103  -11.591 1.000 13.787 0 171 GLN A C   1 ? 
ATOM   1105 O O   . GLN A 1 171 ? -4.697  -4.710  -11.446 1.000 14.250 0 171 GLN A O   1 ? 
ATOM   1106 C CB  . GLN A 1 171 ? -6.721  -6.071  -9.428  1.000 17.849 0 171 GLN A CB  1 ? 
ATOM   1107 C CG  . GLN A 1 171 ? -7.703  -4.948  -9.246  1.000 23.825 0 171 GLN A CG  1 ? 
ATOM   1108 C CD  . GLN A 1 171 ? -7.781  -4.568  -7.787  1.000 29.968 0 171 GLN A CD  1 ? 
ATOM   1109 O OE1 . GLN A 1 171 ? -7.136  -3.608  -7.319  1.000 26.878 0 171 GLN A OE1 1 ? 
ATOM   1110 N NE2 . GLN A 1 171 ? -8.598  -5.351  -7.092  1.000 28.982 0 171 GLN A NE2 1 ? 
ATOM   1111 N N   . SER A 1 172 ? -6.758  -4.436  -12.309 1.000 14.178 0 172 SER A N   1 ? 
ATOM   1112 C CA  . SER A 1 172 ? -6.443  -3.231  -13.049 1.000 13.544 0 172 SER A CA  1 ? 
ATOM   1113 C C   . SER A 1 172 ? -6.614  -2.018  -12.147 1.000 14.045 0 172 SER A C   1 ? 
ATOM   1114 O O   . SER A 1 172 ? -7.579  -1.933  -11.355 1.000 15.177 0 172 SER A O   1 ? 
ATOM   1115 C CB  . SER A 1 172 ? -7.310  -3.072  -14.268 1.000 13.615 0 172 SER A CB  1 ? 
ATOM   1116 O OG  . SER A 1 172 ? -6.917  -1.941  -15.040 1.000 14.383 0 172 SER A OG  1 ? 
ATOM   1117 N N   . LEU A 1 173 ? -5.694  -1.055  -12.327 1.000 11.548 0 173 LEU A N   1 ? 
ATOM   1118 C CA  . LEU A 1 173 ? -5.782  0.289   -11.760 1.000 14.323 0 173 LEU A CA  1 ? 
ATOM   1119 C C   . LEU A 1 173 ? -6.002  1.327   -12.862 1.000 14.000 0 173 LEU A C   1 ? 
ATOM   1120 O O   . LEU A 1 173 ? -5.858  2.555   -12.630 1.000 14.336 0 173 LEU A O   1 ? 
ATOM   1121 C CB  . LEU A 1 173 ? -4.481  0.550   -10.958 1.000 13.987 0 173 LEU A CB  1 ? 
ATOM   1122 C CG  . LEU A 1 173 ? -4.387  -0.184  -9.615  1.000 15.282 0 173 LEU A CG  1 ? 
ATOM   1123 C CD1 . LEU A 1 173 ? -2.996  -0.026  -8.973  1.000 15.324 0 173 LEU A CD1 1 ? 
ATOM   1124 C CD2 . LEU A 1 173 ? -5.504  0.258   -8.677  1.000 17.070 0 173 LEU A CD2 1 ? 
ATOM   1125 N N   . ASN A 1 174 ? -6.355  0.846   -14.088 1.000 14.403 0 174 ASN A N   1 ? 
ATOM   1126 C CA  . ASN A 1 174 ? -6.665  1.704   -15.234 1.000 15.093 0 174 ASN A CA  1 ? 
ATOM   1127 C C   . ASN A 1 174 ? -5.478  2.576   -15.643 1.000 14.750 0 174 ASN A C   1 ? 
ATOM   1128 O O   . ASN A 1 174 ? -4.324  2.229   -15.405 1.000 13.593 0 174 ASN A O   1 ? 
ATOM   1129 C CB  . ASN A 1 174 ? -7.945  2.501   -14.949 1.000 15.222 0 174 ASN A CB  1 ? 
ATOM   1130 C CG  . ASN A 1 174 ? -9.085  1.611   -14.508 1.000 17.605 0 174 ASN A CG  1 ? 
ATOM   1131 O OD1 . ASN A 1 174 ? -9.520  0.726   -15.242 1.000 19.427 0 174 ASN A OD1 1 ? 
ATOM   1132 N ND2 . ASN A 1 174 ? -9.559  1.800   -13.288 1.000 19.644 0 174 ASN A ND2 1 ? 
ATOM   1133 N N   . GLY A 1 175 ? -5.755  3.741   -16.228 1.000 14.494 0 175 GLY A N   1 ? 
ATOM   1134 C CA  . GLY A 1 175 ? -4.720  4.587   -16.754 1.000 15.102 0 175 GLY A CA  1 ? 
ATOM   1135 C C   . GLY A 1 175 ? -4.254  4.101   -18.126 1.000 13.590 0 175 GLY A C   1 ? 
ATOM   1136 O O   . GLY A 1 175 ? -4.677  3.051   -18.589 1.000 15.324 0 175 GLY A O   1 ? 
ATOM   1137 N N   . VAL A 1 176 ? -3.394  4.909   -18.743 1.000 14.948 0 176 VAL A N   1 ? 
ATOM   1138 C CA  . VAL A 1 176 ? -2.735  4.649   -20.020 1.000 15.381 0 176 VAL A CA  1 ? 
ATOM   1139 C C   . VAL A 1 176 ? -1.254  4.952   -19.811 1.000 16.225 0 176 VAL A C   1 ? 
ATOM   1140 O O   . VAL A 1 176 ? -0.881  6.078   -19.532 1.000 16.808 0 176 VAL A O   1 ? 
ATOM   1141 C CB  . VAL A 1 176 ? -3.315  5.458   -21.190 1.000 17.444 0 176 VAL A CB  1 ? 
ATOM   1142 C CG1 . VAL A 1 176 ? -2.645  5.044   -22.501 1.000 18.308 0 176 VAL A CG1 1 ? 
ATOM   1143 C CG2 . VAL A 1 176 ? -4.829  5.317   -21.293 1.000 18.460 0 176 VAL A CG2 1 ? 
ATOM   1144 N N   . LEU A 1 177 ? -0.432  3.910   -19.809 1.000 13.564 0 177 LEU A N   1 ? 
ATOM   1145 C CA  . LEU A 1 177 ? 0.986   4.025   -19.475 1.000 13.771 0 177 LEU A CA  1 ? 
ATOM   1146 C C   . LEU A 1 177 ? 1.865   3.949   -20.715 1.000 13.819 0 177 LEU A C   1 ? 
ATOM   1147 O O   . LEU A 1 177 ? 1.649   3.121   -21.603 1.000 13.812 0 177 LEU A O   1 ? 
ATOM   1148 C CB  . LEU A 1 177 ? 1.373   2.917   -18.488 1.000 13.629 0 177 LEU A CB  1 ? 
ATOM   1149 C CG  . LEU A 1 177 ? 1.092   3.209   -17.000 1.000 15.375 0 177 LEU A CG  1 ? 
ATOM   1150 C CD1 . LEU A 1 177 ? -0.391  3.278   -16.666 1.000 16.182 0 177 LEU A CD1 1 ? 
ATOM   1151 C CD2 . LEU A 1 177 ? 1.719   2.183   -16.119 1.000 16.267 0 177 LEU A CD2 1 ? 
ATOM   1152 N N   . THR A 1 178 ? 2.936   4.774   -20.695 1.000 12.150 0 178 THR A N   1 ? 
ATOM   1153 C CA  . THR A 1 178 ? 3.964   4.765   -21.719 1.000 12.608 0 178 THR A CA  1 ? 
ATOM   1154 C C   . THR A 1 178 ? 5.369   4.685   -21.135 1.000 12.242 0 178 THR A C   1 ? 
ATOM   1155 O O   . THR A 1 178 ? 6.358   5.062   -21.744 1.000 14.645 0 178 THR A O   1 ? 
ATOM   1156 C CB  . THR A 1 178 ? 3.854   6.000   -22.626 1.000 13.372 0 178 THR A CB  1 ? 
ATOM   1157 O OG1 . THR A 1 178 ? 4.070   7.173   -21.836 1.000 14.190 0 178 THR A OG1 1 ? 
ATOM   1158 C CG2 . THR A 1 178 ? 2.500   6.059   -23.295 1.000 14.192 0 178 THR A CG2 1 ? 
ATOM   1159 N N   . SER A 1 179 ? 5.458   4.296   -19.863 1.000 12.763 0 179 SER A N   1 ? 
ATOM   1160 C CA  . SER A 1 179 ? 6.723   4.034   -19.194 1.000 11.683 0 179 SER A CA  1 ? 
ATOM   1161 C C   . SER A 1 179 ? 6.530   2.867   -18.230 1.000 11.838 0 179 SER A C   1 ? 
ATOM   1162 O O   . SER A 1 179 ? 5.404   2.466   -17.943 1.000 12.854 0 179 SER A O   1 ? 
ATOM   1163 C CB  . SER A 1 179 ? 7.225   5.242   -18.430 1.000 12.739 0 179 SER A CB  1 ? 
ATOM   1164 O OG  . SER A 1 179 ? 6.435   5.510   -17.243 1.000 12.391 0 179 SER A OG  1 ? 
ATOM   1165 N N   . ASP A 1 180 ? 7.639   2.420   -17.646 1.000 11.770 0 180 ASP A N   1 ? 
ATOM   1166 C CA  . ASP A 1 180 ? 7.538   1.593   -16.462 1.000 12.476 0 180 ASP A CA  1 ? 
ATOM   1167 C C   . ASP A 1 180 ? 6.874   2.411   -15.366 1.000 12.801 0 180 ASP A C   1 ? 
ATOM   1168 O O   . ASP A 1 180 ? 7.076   3.635   -15.264 1.000 11.633 0 180 ASP A O   1 ? 
ATOM   1169 C CB  . ASP A 1 180 ? 8.901   1.125   -15.939 1.000 11.921 0 180 ASP A CB  1 ? 
ATOM   1170 C CG  . ASP A 1 180 ? 9.614   0.101   -16.804 1.000 14.804 0 180 ASP A CG  1 ? 
ATOM   1171 O OD1 . ASP A 1 180 ? 8.937   -0.571  -17.577 1.000 14.484 0 180 ASP A OD1 1 ? 
ATOM   1172 O OD2 . ASP A 1 180 ? 10.839  -0.031  -16.635 1.000 16.026 0 180 ASP A OD2 1 ? 
ATOM   1173 N N   . PRO A 1 181 ? 6.115   1.766   -14.477 1.000 11.928 0 181 PRO A N   1 ? 
ATOM   1174 C CA  . PRO A 1 181 ? 5.648   2.438   -13.269 1.000 12.112 0 181 PRO A CA  1 ? 
ATOM   1175 C C   . PRO A 1 181 ? 6.803   2.566   -12.292 1.000 11.929 0 181 PRO A C   1 ? 
ATOM   1176 O O   . PRO A 1 181 ? 7.710   1.745   -12.337 1.000 12.276 0 181 PRO A O   1 ? 
ATOM   1177 C CB  . PRO A 1 181 ? 4.557   1.521   -12.752 1.000 12.846 0 181 PRO A CB  1 ? 
ATOM   1178 C CG  . PRO A 1 181 ? 4.928   0.180   -13.268 1.000 13.541 0 181 PRO A CG  1 ? 
ATOM   1179 C CD  . PRO A 1 181 ? 5.652   0.362   -14.585 1.000 12.347 0 181 PRO A CD  1 ? 
ATOM   1180 N N   . THR A 1 182 ? 6.726   3.527   -11.379 1.000 12.049 0 182 THR A N   1 ? 
ATOM   1181 C CA  . THR A 1 182 ? 7.684   3.659   -10.281 1.000 11.315 0 182 THR A CA  1 ? 
ATOM   1182 C C   . THR A 1 182 ? 6.867   3.878   -9.002  1.000 11.313 0 182 THR A C   1 ? 
ATOM   1183 O O   . THR A 1 182 ? 5.883   4.623   -9.008  1.000 12.628 0 182 THR A O   1 ? 
ATOM   1184 C CB  . THR A 1 182 ? 8.716   4.780   -10.550 1.000 11.724 0 182 THR A CB  1 ? 
ATOM   1185 O OG1 . THR A 1 182 ? 9.691   4.880   -9.517  1.000 12.191 0 182 THR A OG1 1 ? 
ATOM   1186 C CG2 . THR A 1 182 ? 8.083   6.145   -10.706 1.000 12.123 0 182 THR A CG2 1 ? 
ATOM   1187 N N   . VAL A 1 183 ? 7.249   3.244   -7.897  1.000 11.090 0 183 VAL A N   1 ? 
ATOM   1188 C CA  . VAL A 1 183 ? 6.425   3.220   -6.698  1.000 10.894 0 183 VAL A CA  1 ? 
ATOM   1189 C C   . VAL A 1 183 ? 7.282   3.536   -5.482  1.000 12.082 0 183 VAL A C   1 ? 
ATOM   1190 O O   . VAL A 1 183 ? 8.439   3.154   -5.409  1.000 12.672 0 183 VAL A O   1 ? 
ATOM   1191 C CB  . VAL A 1 183 ? 5.718   1.857   -6.531  1.000 11.588 0 183 VAL A CB  1 ? 
ATOM   1192 C CG1 . VAL A 1 183 ? 6.709   0.710   -6.452  1.000 12.999 0 183 VAL A CG1 1 ? 
ATOM   1193 C CG2 . VAL A 1 183 ? 4.737   1.836   -5.350  1.000 12.692 0 183 VAL A CG2 1 ? 
ATOM   1194 N N   . TYR A 1 184 ? 6.664   4.204   -4.503  1.000 11.722 0 184 TYR A N   1 ? 
ATOM   1195 C CA  . TYR A 1 184 ? 7.263   4.384   -3.185  1.000 12.611 0 184 TYR A CA  1 ? 
ATOM   1196 C C   . TYR A 1 184 ? 6.159   4.490   -2.148  1.000 13.072 0 184 TYR A C   1 ? 
ATOM   1197 O O   . TYR A 1 184 ? 5.067   4.951   -2.411  1.000 13.618 0 184 TYR A O   1 ? 
ATOM   1198 C CB  . TYR A 1 184 ? 8.153   5.639   -3.100  1.000 12.364 0 184 TYR A CB  1 ? 
ATOM   1199 C CG  . TYR A 1 184 ? 9.470   5.497   -2.355  1.000 13.519 0 184 TYR A CG  1 ? 
ATOM   1200 C CD1 . TYR A 1 184 ? 10.553  4.963   -3.022  1.000 15.957 0 184 TYR A CD1 1 ? 
ATOM   1201 C CD2 . TYR A 1 184 ? 9.574   5.779   -0.982  1.000 14.125 0 184 TYR A CD2 1 ? 
ATOM   1202 C CE1 . TYR A 1 184 ? 11.752  4.791   -2.363  1.000 17.545 0 184 TYR A CE1 1 ? 
ATOM   1203 C CE2 . TYR A 1 184 ? 10.776  5.591   -0.315  1.000 15.644 0 184 TYR A CE2 1 ? 
ATOM   1204 C CZ  . TYR A 1 184 ? 11.849  5.093   -1.027  1.000 17.748 0 184 TYR A CZ  1 ? 
ATOM   1205 O OH  . TYR A 1 184 ? 13.057  4.884   -0.402  1.000 22.207 0 184 TYR A OH  1 ? 
ATOM   1206 N N   . VAL A 1 185 ? 6.521   4.185   -0.897  1.000 12.507 0 185 VAL A N   1 ? 
ATOM   1207 C CA  . VAL A 1 185 ? 5.655   4.432   0.233   1.000 14.066 0 185 VAL A CA  1 ? 
ATOM   1208 C C   . VAL A 1 185 ? 5.560   5.938   0.486   1.000 14.785 0 185 VAL A C   1 ? 
ATOM   1209 O O   . VAL A 1 185 ? 6.577   6.631   0.441   1.000 14.135 0 185 VAL A O   1 ? 
ATOM   1210 C CB  . VAL A 1 185 ? 6.148   3.669   1.474   1.000 13.444 0 185 VAL A CB  1 ? 
ATOM   1211 C CG1 . VAL A 1 185 ? 7.478   4.209   2.035   1.000 14.836 0 185 VAL A CG1 1 ? 
ATOM   1212 C CG2 . VAL A 1 185 ? 5.028   3.664   2.528   1.000 14.925 0 185 VAL A CG2 1 ? 
ATOM   1213 N N   . ASN A 1 186 ? 4.333   6.409   0.730   1.000 14.528 0 186 ASN A N   1 ? 
ATOM   1214 C CA  . ASN A 1 186 ? 4.094   7.814   1.025   1.000 14.568 0 186 ASN A CA  1 ? 
ATOM   1215 C C   . ASN A 1 186 ? 4.040   7.993   2.531   1.000 16.441 0 186 ASN A C   1 ? 
ATOM   1216 O O   . ASN A 1 186 ? 4.254   7.041   3.278   1.000 17.056 0 186 ASN A O   1 ? 
ATOM   1217 C CB  . ASN A 1 186 ? 2.900   8.412   0.277   1.000 14.594 0 186 ASN A CB  1 ? 
ATOM   1218 C CG  . ASN A 1 186 ? 1.544   7.882   0.709   1.000 15.524 0 186 ASN A CG  1 ? 
ATOM   1219 O OD1 . ASN A 1 186 ? 1.383   7.370   1.818   1.000 17.846 0 186 ASN A OD1 1 ? 
ATOM   1220 N ND2 . ASN A 1 186 ? 0.575   7.967   -0.190  1.000 16.281 0 186 ASN A ND2 1 ? 
ATOM   1221 N N   . ALA A 1 187 ? 3.794   9.232   2.948   1.000 17.543 0 187 ALA A N   1 ? 
ATOM   1222 C CA  . ALA A 1 187 ? 3.943   9.545   4.362   1.000 19.033 0 187 ALA A CA  1 ? 
ATOM   1223 C C   . ALA A 1 187 ? 2.788   8.950   5.156   1.000 19.575 0 187 ALA A C   1 ? 
ATOM   1224 O O   . ALA A 1 187 ? 2.877   8.910   6.378   1.000 23.329 0 187 ALA A O   1 ? 
ATOM   1225 C CB  . ALA A 1 187 ? 4.039   11.048  4.542   1.000 20.977 0 187 ALA A CB  1 ? 
ATOM   1226 N N   . SER A 1 188 ? 1.717   8.504   4.510   1.000 19.319 0 188 SER A N   1 ? 
ATOM   1227 C CA  . SER A 1 188 ? 0.635   7.792   5.175   1.000 20.028 0 188 SER A CA  1 ? 
ATOM   1228 C C   . SER A 1 188 ? 0.945   6.292   5.285   1.000 20.743 0 188 SER A C   1 ? 
ATOM   1229 O O   . SER A 1 188 ? 0.120   5.557   5.809   1.000 20.617 0 188 SER A O   1 ? 
ATOM   1230 C CB  . SER A 1 188 ? -0.646  8.033   4.439   1.000 22.799 0 188 SER A CB  1 ? 
ATOM   1231 O OG  . SER A 1 188 ? -0.684  7.229   3.249   1.000 28.517 0 188 SER A OG  1 ? 
ATOM   1232 N N   . GLY A 1 189 ? 2.117   5.807   4.816   1.000 18.113 0 189 GLY A N   1 ? 
ATOM   1233 C CA  . GLY A 1 189 ? 2.474   4.395   4.911   1.000 17.738 0 189 GLY A CA  1 ? 
ATOM   1234 C C   . GLY A 1 189 ? 1.815   3.544   3.838   1.000 17.174 0 189 GLY A C   1 ? 
ATOM   1235 O O   . GLY A 1 189 ? 1.739   2.333   3.981   1.000 18.630 0 189 GLY A O   1 ? 
ATOM   1236 N N   . ARG A 1 190 ? 1.384   4.177   2.741   1.000 16.195 0 190 ARG A N   1 ? 
ATOM   1237 C CA  . ARG A 1 190 ? 0.722   3.463   1.661   1.000 15.541 0 190 ARG A CA  1 ? 
ATOM   1238 C C   . ARG A 1 190 ? 1.421   3.736   0.325   1.000 13.777 0 190 ARG A C   1 ? 
ATOM   1239 O O   . ARG A 1 190 ? 2.142   4.709   0.179   1.000 15.225 0 190 ARG A O   1 ? 
ATOM   1240 C CB  . ARG A 1 190 ? -0.737  3.901   1.550   1.000 18.779 0 190 ARG A CB  1 ? 
ATOM   1241 C CG  . ARG A 1 190 ? -1.600  3.387   2.699   1.000 20.900 0 190 ARG A CG  1 ? 
ATOM   1242 C CD  . ARG A 1 190 ? -3.035  3.787   2.550   1.000 22.997 0 190 ARG A CD  1 ? 
ATOM   1243 N NE  . ARG A 1 190 ? -3.744  3.406   3.785   1.000 24.110 0 190 ARG A NE  1 ? 
ATOM   1244 C CZ  . ARG A 1 190 ? -4.231  2.204   4.036   1.000 23.996 0 190 ARG A CZ  1 ? 
ATOM   1245 N NH1 . ARG A 1 190 ? -4.144  1.221   3.149   1.000 23.332 0 190 ARG A NH1 1 ? 
ATOM   1246 N NH2 . ARG A 1 190 ? -4.844  1.991   5.197   1.000 24.454 0 190 ARG A NH2 1 ? 
ATOM   1247 N N   . PRO A 1 191 ? 1.254   2.837   -0.677  1.000 12.512 0 191 PRO A N   1 ? 
ATOM   1248 C CA  . PRO A 1 191 ? 1.941   3.016   -1.953  1.000 12.342 0 191 PRO A CA  1 ? 
ATOM   1249 C C   . PRO A 1 191 ? 1.386   4.137   -2.822  1.000 12.881 0 191 PRO A C   1 ? 
ATOM   1250 O O   . PRO A 1 191 ? 0.191   4.390   -2.851  1.000 12.795 0 191 PRO A O   1 ? 
ATOM   1251 C CB  . PRO A 1 191 ? 1.736   1.696   -2.654  1.000 12.316 0 191 PRO A CB  1 ? 
ATOM   1252 C CG  . PRO A 1 191 ? 0.458   1.183   -2.105  1.000 13.054 0 191 PRO A CG  1 ? 
ATOM   1253 C CD  . PRO A 1 191 ? 0.569   1.546   -0.627  1.000 13.250 0 191 PRO A CD  1 ? 
ATOM   1254 N N   . GLU A 1 192 ? 2.308   4.788   -3.499  1.000 12.363 0 192 GLU A N   1 ? 
ATOM   1255 C CA  . GLU A 1 192 ? 1.987   5.785   -4.484  1.000 12.445 0 192 GLU A CA  1 ? 
ATOM   1256 C C   . GLU A 1 192 ? 2.775   5.436   -5.739  1.000 11.845 0 192 GLU A C   1 ? 
ATOM   1257 O O   . GLU A 1 192 ? 3.987   5.259   -5.682  1.000 12.857 0 192 GLU A O   1 ? 
ATOM   1258 C CB  . GLU A 1 192 ? 2.327   7.170   -3.937  1.000 13.899 0 192 GLU A CB  1 ? 
ATOM   1259 C CG  . GLU A 1 192 ? 1.921   8.342   -4.805  1.000 14.129 0 192 GLU A CG  1 ? 
ATOM   1260 C CD  . GLU A 1 192 ? 1.636   9.647   -4.061  1.000 16.290 0 192 GLU A CD  1 ? 
ATOM   1261 O OE1 . GLU A 1 192 ? 1.432   9.590   -2.857  1.000 16.193 0 192 GLU A OE1 1 ? 
ATOM   1262 O OE2 . GLU A 1 192 ? 1.586   10.709  -4.749  1.000 17.859 0 192 GLU A OE2 1 ? 
ATOM   1263 N N   . VAL A 1 193 ? 2.064   5.358   -6.873  1.000 12.078 0 193 VAL A N   1 ? 
ATOM   1264 C CA  . VAL A 1 193 ? 2.615   4.890   -8.125  1.000 11.636 0 193 VAL A CA  1 ? 
ATOM   1265 C C   . VAL A 1 193 ? 2.523   5.983   -9.170  1.000 11.256 0 193 VAL A C   1 ? 
ATOM   1266 O O   . VAL A 1 193 ? 1.470   6.626   -9.294  1.000 13.371 0 193 VAL A O   1 ? 
ATOM   1267 C CB  . VAL A 1 193 ? 1.879   3.626   -8.634  1.000 11.529 0 193 VAL A CB  1 ? 
ATOM   1268 C CG1 . VAL A 1 193 ? 2.546   3.020   -9.844  1.000 12.788 0 193 VAL A CG1 1 ? 
ATOM   1269 C CG2 . VAL A 1 193 ? 1.752   2.556   -7.554  1.000 13.040 0 193 VAL A CG2 1 ? 
ATOM   1270 N N   . PHE A 1 194 ? 3.607   6.136   -9.920  1.000 10.246 0 194 PHE A N   1 ? 
ATOM   1271 C CA  . PHE A 1 194 ? 3.781   7.172   -10.928 1.000 11.152 0 194 PHE A CA  1 ? 
ATOM   1272 C C   . PHE A 1 194 ? 4.134   6.532   -12.261 1.000 12.196 0 194 PHE A C   1 ? 
ATOM   1273 O O   . PHE A 1 194 ? 4.827   5.516   -12.315 1.000 12.356 0 194 PHE A O   1 ? 
ATOM   1274 C CB  . PHE A 1 194 ? 4.907   8.138   -10.565 1.000 11.577 0 194 PHE A CB  1 ? 
ATOM   1275 C CG  . PHE A 1 194 ? 4.744   8.796   -9.223  1.000 11.019 0 194 PHE A CG  1 ? 
ATOM   1276 C CD1 . PHE A 1 194 ? 4.980   8.098   -8.067  1.000 12.214 0 194 PHE A CD1 1 ? 
ATOM   1277 C CD2 . PHE A 1 194 ? 4.393   10.121  -9.134  1.000 10.952 0 194 PHE A CD2 1 ? 
ATOM   1278 C CE1 . PHE A 1 194 ? 4.862   8.695   -6.832  1.000 12.285 0 194 PHE A CE1 1 ? 
ATOM   1279 C CE2 . PHE A 1 194 ? 4.305   10.728  -7.898  1.000 11.792 0 194 PHE A CE2 1 ? 
ATOM   1280 C CZ  . PHE A 1 194 ? 4.498   10.020  -6.751  1.000 12.364 0 194 PHE A CZ  1 ? 
ATOM   1281 N N   . ALA A 1 195 ? 3.652   7.127   -13.340 1.000 11.002 0 195 ALA A N   1 ? 
ATOM   1282 C CA  . ALA A 1 195 ? 4.007   6.644   -14.665 1.000 11.534 0 195 ALA A CA  1 ? 
ATOM   1283 C C   . ALA A 1 195 ? 3.834   7.762   -15.670 1.000 11.675 0 195 ALA A C   1 ? 
ATOM   1284 O O   . ALA A 1 195 ? 3.006   8.632   -15.469 1.000 14.440 0 195 ALA A O   1 ? 
ATOM   1285 C CB  . ALA A 1 195 ? 3.174   5.465   -15.046 1.000 12.021 0 195 ALA A CB  1 ? 
ATOM   1286 N N   . ARG A 1 196 ? 4.521   7.652   -16.798 1.000 11.992 0 196 ARG A N   1 ? 
ATOM   1287 C CA  . ARG A 1 196 ? 4.266   8.509   -17.939 1.000 12.083 0 196 ARG A CA  1 ? 
ATOM   1288 C C   . ARG A 1 196 ? 3.038   7.992   -18.662 1.000 11.944 0 196 ARG A C   1 ? 
ATOM   1289 O O   . ARG A 1 196 ? 2.788   6.793   -18.723 1.000 11.747 0 196 ARG A O   1 ? 
ATOM   1290 C CB  . ARG A 1 196 ? 5.446   8.508   -18.912 1.000 12.314 0 196 ARG A CB  1 ? 
ATOM   1291 C CG  . ARG A 1 196 ? 5.381   9.626   -19.960 1.000 12.743 0 196 ARG A CG  1 ? 
ATOM   1292 C CD  . ARG A 1 196 ? 6.591   9.712   -20.866 1.000 14.477 0 196 ARG A CD  1 ? 
ATOM   1293 N NE  . ARG A 1 196 ? 6.611   8.537   -21.711 1.000 13.785 0 196 ARG A NE  1 ? 
ATOM   1294 C CZ  . ARG A 1 196 ? 7.483   8.356   -22.682 1.000 15.533 0 196 ARG A CZ  1 ? 
ATOM   1295 N NH1 . ARG A 1 196 ? 8.478   9.204   -22.849 1.000 14.118 0 196 ARG A NH1 1 ? 
ATOM   1296 N NH2 . ARG A 1 196 ? 7.436   7.245   -23.395 1.000 17.186 0 196 ARG A NH2 1 ? 
ATOM   1297 N N   . SER A 1 197 ? 2.229   8.940   -19.188 1.000 11.592 0 197 SER A N   1 ? 
ATOM   1298 C CA  . SER A 1 197 ? 1.026   8.613   -19.944 1.000 12.398 0 197 SER A CA  1 ? 
ATOM   1299 C C   . SER A 1 197 ? 1.189   8.956   -21.413 1.000 12.375 0 197 SER A C   1 ? 
ATOM   1300 O O   . SER A 1 197 ? 2.263   9.358   -21.842 1.000 13.420 0 197 SER A O   1 ? 
ATOM   1301 C CB  . SER A 1 197 ? -0.192  9.252   -19.334 1.000 13.317 0 197 SER A CB  1 ? 
ATOM   1302 O OG  . SER A 1 197 ? -1.394  8.693   -19.859 1.000 13.882 0 197 SER A OG  1 ? 
ATOM   1303 N N   . ASN A 1 198 ? 0.105   8.851   -22.173 1.000 13.818 0 198 ASN A N   1 ? 
ATOM   1304 C CA  . ASN A 1 198 ? 0.196   9.047   -23.613 1.000 14.995 0 198 ASN A CA  1 ? 
ATOM   1305 C C   . ASN A 1 198 ? 0.174   10.522  -24.013 1.000 14.964 0 198 ASN A C   1 ? 
ATOM   1306 O O   . ASN A 1 198 ? 0.373   10.858  -25.182 1.000 18.917 0 198 ASN A O   1 ? 
ATOM   1307 C CB  . ASN A 1 198 ? -0.870  8.241   -24.334 1.000 16.849 0 198 ASN A CB  1 ? 
ATOM   1308 C CG  . ASN A 1 198 ? -2.276  8.662   -24.012 1.000 19.739 0 198 ASN A CG  1 ? 
ATOM   1309 O OD1 . ASN A 1 198 ? -2.553  9.327   -23.018 1.000 21.457 0 198 ASN A OD1 1 ? 
ATOM   1310 N ND2 . ASN A 1 198 ? -3.209  8.191   -24.811 1.000 27.390 0 198 ASN A ND2 1 ? 
ATOM   1311 N N   . ASP A 1 199 ? 0.098   11.437  -23.043 1.000 14.527 0 199 ASP A N   1 ? 
ATOM   1312 C CA  . ASP A 1 199 ? 0.364   12.856  -23.242 1.000 15.994 0 199 ASP A CA  1 ? 
ATOM   1313 C C   . ASP A 1 199 ? 1.805   13.232  -22.892 1.000 15.332 0 199 ASP A C   1 ? 
ATOM   1314 O O   . ASP A 1 199 ? 2.169   14.415  -22.875 1.000 15.660 0 199 ASP A O   1 ? 
ATOM   1315 C CB  . ASP A 1 199 ? -0.643  13.650  -22.398 1.000 15.748 0 199 ASP A CB  1 ? 
ATOM   1316 C CG  . ASP A 1 199 ? -0.594  13.379  -20.890 1.000 16.280 0 199 ASP A CG  1 ? 
ATOM   1317 O OD1 . ASP A 1 199 ? 0.264   12.517  -20.463 1.000 15.413 0 199 ASP A OD1 1 ? 
ATOM   1318 O OD2 . ASP A 1 199 ? -1.467  13.977  -20.154 1.000 15.539 0 199 ASP A OD2 1 ? 
ATOM   1319 N N   . TYR A 1 200 ? 2.618   12.198  -22.565 1.000 13.268 0 200 TYR A N   1 ? 
ATOM   1320 C CA  . TYR A 1 200 ? 4.020   12.342  -22.188 1.000 14.887 0 200 TYR A CA  1 ? 
ATOM   1321 C C   . TYR A 1 200 ? 4.202   13.032  -20.835 1.000 13.621 0 200 TYR A C   1 ? 
ATOM   1322 O O   . TYR A 1 200 ? 5.322   13.383  -20.484 1.000 13.842 0 200 TYR A O   1 ? 
ATOM   1323 C CB  . TYR A 1 200 ? 4.914   13.022  -23.210 1.000 17.386 0 200 TYR A CB  1 ? 
ATOM   1324 C CG  . TYR A 1 200 ? 5.019   12.235  -24.501 1.000 21.618 0 200 TYR A CG  1 ? 
ATOM   1325 C CD1 . TYR A 1 200 ? 6.000   11.267  -24.649 1.000 26.749 0 200 TYR A CD1 1 ? 
ATOM   1326 C CD2 . TYR A 1 200 ? 4.086   12.385  -25.520 1.000 23.678 0 200 TYR A CD2 1 ? 
ATOM   1327 C CE1 . TYR A 1 200 ? 6.079   10.501  -25.804 1.000 30.239 0 200 TYR A CE1 1 ? 
ATOM   1328 C CE2 . TYR A 1 200 ? 4.162   11.637  -26.682 1.000 26.137 0 200 TYR A CE2 1 ? 
ATOM   1329 C CZ  . TYR A 1 200 ? 5.162   10.693  -26.824 1.000 33.642 0 200 TYR A CZ  1 ? 
ATOM   1330 O OH  . TYR A 1 200 ? 5.226   9.952   -27.974 1.000 34.207 0 200 TYR A OH  1 ? 
ATOM   1331 N N   . SER A 1 201 ? 3.113   13.184  -20.093 1.000 12.441 0 201 SER A N   1 ? 
ATOM   1332 C CA  . SER A 1 201 ? 3.149   13.765  -18.760 1.000 11.665 0 201 SER A CA  1 ? 
ATOM   1333 C C   . SER A 1 201 ? 3.241   12.680  -17.698 1.000 11.933 0 201 SER A C   1 ? 
ATOM   1334 O O   . SER A 1 201 ? 2.947   11.521  -17.948 1.000 11.535 0 201 SER A O   1 ? 
ATOM   1335 C CB  . SER A 1 201 ? 1.950   14.632  -18.487 1.000 11.316 0 201 SER A CB  1 ? 
ATOM   1336 O OG  . SER A 1 201 ? 1.956   15.848  -19.258 1.000 13.628 0 201 SER A OG  1 ? 
ATOM   1337 N N   . LEU A 1 202 ? 3.659   13.128  -16.495 1.000 11.301 0 202 LEU A N   1 ? 
ATOM   1338 C CA  . LEU A 1 202 ? 3.727   12.268  -15.318 1.000 12.619 0 202 LEU A CA  1 ? 
ATOM   1339 C C   . LEU A 1 202 ? 2.359   12.258  -14.629 1.000 12.016 0 202 LEU A C   1 ? 
ATOM   1340 O O   . LEU A 1 202 ? 1.796   13.330  -14.339 1.000 12.903 0 202 LEU A O   1 ? 
ATOM   1341 C CB  . LEU A 1 202 ? 4.808   12.805  -14.382 1.000 13.169 0 202 LEU A CB  1 ? 
ATOM   1342 C CG  . LEU A 1 202 ? 5.042   11.952  -13.138 1.000 15.611 0 202 LEU A CG  1 ? 
ATOM   1343 C CD1 . LEU A 1 202 ? 5.696   10.643  -13.501 1.000 15.554 0 202 LEU A CD1 1 ? 
ATOM   1344 C CD2 . LEU A 1 202 ? 5.862   12.739  -12.129 1.000 16.613 0 202 LEU A CD2 1 ? 
ATOM   1345 N N   . TRP A 1 203 ? 1.847   11.087  -14.309 1.000 12.068 0 203 TRP A N   1 ? 
ATOM   1346 C CA  . TRP A 1 203 ? 0.594   10.935  -13.571 1.000 12.682 0 203 TRP A CA  1 ? 
ATOM   1347 C C   . TRP A 1 203 ? 0.837   10.025  -12.367 1.000 12.901 0 203 TRP A C   1 ? 
ATOM   1348 O O   . TRP A 1 203 ? 1.788   9.237   -12.371 1.000 12.934 0 203 TRP A O   1 ? 
ATOM   1349 C CB  . TRP A 1 203 ? -0.506  10.329  -14.469 1.000 13.220 0 203 TRP A CB  1 ? 
ATOM   1350 C CG  . TRP A 1 203 ? -0.981  11.212  -15.601 1.000 12.674 0 203 TRP A CG  1 ? 
ATOM   1351 C CD1 . TRP A 1 203 ? -0.320  11.526  -16.759 1.000 13.753 0 203 TRP A CD1 1 ? 
ATOM   1352 C CD2 . TRP A 1 203 ? -2.281  11.817  -15.703 1.000 12.437 0 203 TRP A CD2 1 ? 
ATOM   1353 N NE1 . TRP A 1 203 ? -1.121  12.311  -17.537 1.000 14.665 0 203 TRP A NE1 1 ? 
ATOM   1354 C CE2 . TRP A 1 203 ? -2.339  12.476  -16.938 1.000 13.944 0 203 TRP A CE2 1 ? 
ATOM   1355 C CE3 . TRP A 1 203 ? -3.396  11.833  -14.880 1.000 12.584 0 203 TRP A CE3 1 ? 
ATOM   1356 C CZ2 . TRP A 1 203 ? -3.480  13.165  -17.350 1.000 15.440 0 203 TRP A CZ2 1 ? 
ATOM   1357 C CZ3 . TRP A 1 203 ? -4.529  12.503  -15.295 1.000 13.753 0 203 TRP A CZ3 1 ? 
ATOM   1358 C CH2 . TRP A 1 203 ? -4.571  13.131  -16.536 1.000 15.475 0 203 TRP A CH2 1 ? 
ATOM   1359 N N   . TYR A 1 204 ? -0.009  10.123  -11.338 1.000 13.455 0 204 TYR A N   1 ? 
ATOM   1360 C CA  . TYR A 1 204 ? 0.135   9.241   -10.188 1.000 12.897 0 204 TYR A CA  1 ? 
ATOM   1361 C C   . TYR A 1 204 ? -1.234  8.790   -9.674  1.000 12.978 0 204 TYR A C   1 ? 
ATOM   1362 O O   . TYR A 1 204 ? -2.262  9.437   -9.894  1.000 13.815 0 204 TYR A O   1 ? 
ATOM   1363 C CB  . TYR A 1 204 ? 0.943   9.917   -9.072  1.000 13.624 0 204 TYR A CB  1 ? 
ATOM   1364 C CG  . TYR A 1 204 ? 0.254   11.057  -8.358  1.000 14.527 0 204 TYR A CG  1 ? 
ATOM   1365 C CD1 . TYR A 1 204 ? -0.561  10.809  -7.253  1.000 17.819 0 204 TYR A CD1 1 ? 
ATOM   1366 C CD2 . TYR A 1 204 ? 0.408   12.361  -8.774  1.000 16.909 0 204 TYR A CD2 1 ? 
ATOM   1367 C CE1 . TYR A 1 204 ? -1.172  11.846  -6.562  1.000 19.798 0 204 TYR A CE1 1 ? 
ATOM   1368 C CE2 . TYR A 1 204 ? -0.208  13.411  -8.093  1.000 19.559 0 204 TYR A CE2 1 ? 
ATOM   1369 C CZ  . TYR A 1 204 ? -0.990  13.142  -6.981  1.000 21.870 0 204 TYR A CZ  1 ? 
ATOM   1370 O OH  . TYR A 1 204 ? -1.603  14.151  -6.282  1.000 24.081 0 204 TYR A OH  1 ? 
ATOM   1371 N N   . ILE A 1 205 ? -1.183  7.714   -8.905  1.000 13.292 0 205 ILE A N   1 ? 
ATOM   1372 C CA  . ILE A 1 205 ? -2.312  7.141   -8.215  1.000 13.163 0 205 ILE A CA  1 ? 
ATOM   1373 C C   . ILE A 1 205 ? -1.794  6.727   -6.848  1.000 13.928 0 205 ILE A C   1 ? 
ATOM   1374 O O   . ILE A 1 205 ? -0.603  6.477   -6.692  1.000 14.486 0 205 ILE A O   1 ? 
ATOM   1375 C CB  . ILE A 1 205 ? -2.913  6.010   -9.074  1.000 16.254 0 205 ILE A CB  1 ? 
ATOM   1376 C CG1 . ILE A 1 205 ? -4.302  5.569   -8.661  1.000 19.937 0 205 ILE A CG1 1 ? 
ATOM   1377 C CG2 . ILE A 1 205 ? -1.959  4.826   -9.180  1.000 16.249 0 205 ILE A CG2 1 ? 
ATOM   1378 C CD1 . ILE A 1 205 ? -4.973  4.618   -9.675  1.000 20.735 0 205 ILE A CD1 1 ? 
ATOM   1379 N N   . LYS A 1 206 ? -2.668  6.644   -5.846  1.000 13.704 0 206 LYS A N   1 ? 
ATOM   1380 C CA  . LYS A 1 206 ? -2.186  6.183   -4.557  1.000 14.765 0 206 LYS A CA  1 ? 
ATOM   1381 C C   . LYS A 1 206 ? -3.308  5.469   -3.822  1.000 16.277 0 206 LYS A C   1 ? 
ATOM   1382 O O   . LYS A 1 206 ? -4.476  5.631   -4.156  1.000 15.992 0 206 LYS A O   1 ? 
ATOM   1383 C CB  . LYS A 1 206 ? -1.701  7.318   -3.670  1.000 15.773 0 206 LYS A CB  1 ? 
ATOM   1384 C CG  . LYS A 1 206 ? -2.774  8.347   -3.340  1.000 16.972 0 206 LYS A CG  1 ? 
ATOM   1385 C CD  . LYS A 1 206 ? -2.249  9.495   -2.498  1.000 18.005 0 206 LYS A CD  1 ? 
ATOM   1386 C CE  . LYS A 1 206 ? -3.347  10.503  -2.230  1.000 18.731 0 206 LYS A CE  1 ? 
ATOM   1387 N NZ  . LYS A 1 206 ? -2.802  11.736  -1.645  1.000 20.589 0 206 LYS A NZ  1 ? 
ATOM   1388 N N   . GLN A 1 207 ? -2.907  4.661   -2.846  1.000 16.068 0 207 GLN A N   1 ? 
ATOM   1389 C CA  . GLN A 1 207 ? -3.831  3.859   -2.072  1.000 15.874 0 207 GLN A CA  1 ? 
ATOM   1390 C C   . GLN A 1 207 ? -4.220  4.654   -0.835  1.000 17.713 0 207 GLN A C   1 ? 
ATOM   1391 O O   . GLN A 1 207 ? -3.425  5.419   -0.333  1.000 17.076 0 207 GLN A O   1 ? 
ATOM   1392 C CB  . GLN A 1 207 ? -3.163  2.547   -1.681  1.000 17.410 0 207 GLN A CB  1 ? 
ATOM   1393 C CG  . GLN A 1 207 ? -4.108  1.549   -1.018  1.000 19.785 0 207 GLN A CG  1 ? 
ATOM   1394 C CD  . GLN A 1 207 ? -3.262  0.468   -0.397  1.000 23.510 0 207 GLN A CD  1 ? 
ATOM   1395 O OE1 . GLN A 1 207 ? -2.657  0.657   0.644   1.000 21.104 0 207 GLN A OE1 1 ? 
ATOM   1396 N NE2 . GLN A 1 207 ? -3.096  -0.627  -1.116  1.000 31.559 0 207 GLN A NE2 1 ? 
ATOM   1397 N N   . THR A 1 208 ? -5.490  4.521   -0.429  1.000 20.317 0 208 THR A N   1 ? 
ATOM   1398 C CA  . THR A 1 208 ? -6.009  5.192   0.748   1.000 22.600 0 208 THR A CA  1 ? 
ATOM   1399 C C   . THR A 1 208 ? -6.572  4.128   1.676   1.000 22.653 0 208 THR A C   1 ? 
ATOM   1400 O O   . THR A 1 208 ? -6.557  2.933   1.362   1.000 21.876 0 208 THR A O   1 ? 
ATOM   1401 C CB  . THR A 1 208 ? -7.119  6.202   0.396   1.000 24.946 0 208 THR A CB  1 ? 
ATOM   1402 O OG1 . THR A 1 208 ? -8.263  5.428   0.045   1.000 25.682 0 208 THR A OG1 1 ? 
ATOM   1403 C CG2 . THR A 1 208 ? -6.745  7.106   -0.753  1.000 27.202 0 208 THR A CG2 1 ? 
ATOM   1404 N N   . ALA A 1 209 ? -7.186  4.602   2.761   1.000 26.348 0 209 ALA A N   1 ? 
ATOM   1405 C CA  . ALA A 1 209 ? -7.891  3.732   3.699   1.000 30.046 0 209 ALA A CA  1 ? 
ATOM   1406 C C   . ALA A 1 209 ? -9.330  3.404   3.284   1.000 29.851 0 209 ALA A C   1 ? 
ATOM   1407 O O   . ALA A 1 209 ? -9.972  2.535   3.878   1.000 30.304 0 209 ALA A O   1 ? 
ATOM   1408 C CB  . ALA A 1 209 ? -7.837  4.412   5.047   1.000 29.820 0 209 ALA A CB  1 ? 
ATOM   1409 N N   . SER A 1 210 ? -9.843  4.025   2.228   1.000 29.828 0 210 SER A N   1 ? 
ATOM   1410 C CA  . SER A 1 210 ? -11.249 3.902   1.843   1.000 26.334 0 210 SER A CA  1 ? 
ATOM   1411 C C   . SER A 1 210 ? -11.583 2.500   1.330   1.000 30.709 0 210 SER A C   1 ? 
ATOM   1412 O O   . SER A 1 210 ? -10.815 1.898   0.586   1.000 27.966 0 210 SER A O   1 ? 
ATOM   1413 C CB  . SER A 1 210 ? -11.594 4.978   0.835   1.000 27.633 0 210 SER A CB  1 ? 
ATOM   1414 O OG  . SER A 1 210 ? -12.802 4.681   0.162   1.000 27.966 0 210 SER A OG  1 ? 
ATOM   1415 N N   . HIS A 1 211 ? -12.771 1.975   1.686   1.000 32.216 0 211 HIS A N   1 ? 
ATOM   1416 C CA  . HIS A 1 211 ? -13.181 0.679   1.167   1.000 35.542 0 211 HIS A CA  1 ? 
ATOM   1417 C C   . HIS A 1 211 ? -13.816 0.847   -0.203  1.000 33.088 0 211 HIS A C   1 ? 
ATOM   1418 O O   . HIS A 1 211 ? -13.784 -0.073  -1.016  1.000 36.124 0 211 HIS A O   1 ? 
ATOM   1419 C CB  . HIS A 1 211 ? -14.100 -0.050  2.159   1.000 46.311 0 211 HIS A CB  1 ? 
ATOM   1420 C CG  . HIS A 1 211 ? -13.348 -0.566  3.342   1.000 55.137 0 211 HIS A CG  1 ? 
ATOM   1421 N ND1 . HIS A 1 211 ? -13.733 -0.359  4.651   1.000 64.278 0 211 HIS A ND1 1 ? 
ATOM   1422 C CD2 . HIS A 1 211 ? -12.210 -1.279  3.394   1.000 59.532 0 211 HIS A CD2 1 ? 
ATOM   1423 C CE1 . HIS A 1 211 ? -12.853 -0.931  5.461   1.000 66.613 0 211 HIS A CE1 1 ? 
ATOM   1424 N NE2 . HIS A 1 211 ? -11.918 -1.491  4.717   1.000 66.585 0 211 HIS A NE2 1 ? 
ATOM   1425 N N   . THR A 1 212 ? -14.420 2.016   -0.432  1.000 30.325 0 212 THR A N   1 ? 
ATOM   1426 C CA  . THR A 1 212 ? -15.123 2.291   -1.671  1.000 28.213 0 212 THR A CA  1 ? 
ATOM   1427 C C   . THR A 1 212 ? -14.181 2.800   -2.751  1.000 25.555 0 212 THR A C   1 ? 
ATOM   1428 O O   . THR A 1 212 ? -14.414 2.528   -3.931  1.000 24.370 0 212 THR A O   1 ? 
ATOM   1429 C CB  . THR A 1 212 ? -16.231 3.326   -1.456  1.000 30.854 0 212 THR A CB  1 ? 
ATOM   1430 O OG1 . THR A 1 212 ? -17.011 2.886   -0.342  1.000 42.821 0 212 THR A OG1 1 ? 
ATOM   1431 C CG2 . THR A 1 212 ? -17.091 3.469   -2.688  1.000 36.393 0 212 THR A CG2 1 ? 
ATOM   1432 N N   . TYR A 1 213 ? -13.166 3.584   -2.335  1.000 23.111 0 213 TYR A N   1 ? 
ATOM   1433 C CA  . TYR A 1 213 ? -12.193 4.135   -3.271  1.000 22.844 0 213 TYR A CA  1 ? 
ATOM   1434 C C   . TYR A 1 213 ? -10.792 3.859   -2.733  1.000 21.140 0 213 TYR A C   1 ? 
ATOM   1435 O O   . TYR A 1 213 ? -10.066 4.784   -2.351  1.000 19.744 0 213 TYR A O   1 ? 
ATOM   1436 C CB  . TYR A 1 213 ? -12.422 5.636   -3.496  1.000 21.228 0 213 TYR A CB  1 ? 
ATOM   1437 C CG  . TYR A 1 213 ? -13.735 5.869   -4.238  1.000 19.845 0 213 TYR A CG  1 ? 
ATOM   1438 C CD1 . TYR A 1 213 ? -13.805 5.672   -5.610  1.000 20.144 0 213 TYR A CD1 1 ? 
ATOM   1439 C CD2 . TYR A 1 213 ? -14.916 6.163   -3.547  1.000 21.045 0 213 TYR A CD2 1 ? 
ATOM   1440 C CE1 . TYR A 1 213 ? -15.006 5.805   -6.289  1.000 20.805 0 213 TYR A CE1 1 ? 
ATOM   1441 C CE2 . TYR A 1 213 ? -16.123 6.310   -4.222  1.000 21.999 0 213 TYR A CE2 1 ? 
ATOM   1442 C CZ  . TYR A 1 213 ? -16.163 6.094   -5.590  1.000 21.932 0 213 TYR A CZ  1 ? 
ATOM   1443 O OH  . TYR A 1 213 ? -17.330 6.250   -6.308  1.000 20.690 0 213 TYR A OH  1 ? 
ATOM   1444 N N   . PRO A 1 214 ? -10.393 2.572   -2.675  1.000 20.947 0 214 PRO A N   1 ? 
ATOM   1445 C CA  . PRO A 1 214 ? -9.103  2.198   -2.097  1.000 19.648 0 214 PRO A CA  1 ? 
ATOM   1446 C C   . PRO A 1 214 ? -7.955  2.845   -2.859  1.000 19.157 0 214 PRO A C   1 ? 
ATOM   1447 O O   . PRO A 1 214 ? -6.932  3.130   -2.282  1.000 19.617 0 214 PRO A O   1 ? 
ATOM   1448 C CB  . PRO A 1 214 ? -9.071  0.673   -2.203  1.000 21.619 0 214 PRO A CB  1 ? 
ATOM   1449 C CG  . PRO A 1 214 ? -10.068 0.347   -3.297  1.000 23.650 0 214 PRO A CG  1 ? 
ATOM   1450 C CD  . PRO A 1 214 ? -11.164 1.395   -3.129  1.000 22.643 0 214 PRO A CD  1 ? 
ATOM   1451 N N   . TRP A 1 215 ? -8.117  3.013   -4.164  1.000 16.758 0 215 TRP A N   1 ? 
ATOM   1452 C CA  . TRP A 1 215 ? -7.137  3.752   -4.915  1.000 16.975 0 215 TRP A CA  1 ? 
ATOM   1453 C C   . TRP A 1 215 ? -7.761  5.006   -5.493  1.000 15.413 0 215 TRP A C   1 ? 
ATOM   1454 O O   . TRP A 1 215 ? -8.932  4.957   -5.896  1.000 17.181 0 215 TRP A O   1 ? 
ATOM   1455 C CB  . TRP A 1 215 ? -6.581  2.851   -6.023  1.000 16.161 0 215 TRP A CB  1 ? 
ATOM   1456 C CG  . TRP A 1 215 ? -5.667  1.759   -5.529  1.000 15.515 0 215 TRP A CG  1 ? 
ATOM   1457 C CD1 . TRP A 1 215 ? -6.031  0.543   -5.037  1.000 17.305 0 215 TRP A CD1 1 ? 
ATOM   1458 C CD2 . TRP A 1 215 ? -4.226  1.782   -5.504  1.000 15.061 0 215 TRP A CD2 1 ? 
ATOM   1459 N NE1 . TRP A 1 215 ? -4.917  -0.171  -4.661  1.000 17.208 0 215 TRP A NE1 1 ? 
ATOM   1460 C CE2 . TRP A 1 215 ? -3.796  0.538   -4.979  1.000 14.907 0 215 TRP A CE2 1 ? 
ATOM   1461 C CE3 . TRP A 1 215 ? -3.271  2.725   -5.886  1.000 14.877 0 215 TRP A CE3 1 ? 
ATOM   1462 C CZ2 . TRP A 1 215 ? -2.448  0.250   -4.807  1.000 15.176 0 215 TRP A CZ2 1 ? 
ATOM   1463 C CZ3 . TRP A 1 215 ? -1.939  2.409   -5.758  1.000 15.315 0 215 TRP A CZ3 1 ? 
ATOM   1464 C CH2 . TRP A 1 215 ? -1.538  1.181   -5.235  1.000 16.412 0 215 TRP A CH2 1 ? 
ATOM   1465 N N   . THR A 1 216 ? -7.012  6.111   -5.494  1.000 13.928 0 216 THR A N   1 ? 
ATOM   1466 C CA  . THR A 1 216 ? -7.481  7.366   -6.046  1.000 13.707 0 216 THR A CA  1 ? 
ATOM   1467 C C   . THR A 1 216 ? -7.641  7.293   -7.554  1.000 14.621 0 216 THR A C   1 ? 
ATOM   1468 O O   . THR A 1 216 ? -7.151  6.360   -8.183  1.000 15.405 0 216 THR A O   1 ? 
ATOM   1469 C CB  . THR A 1 216 ? -6.534  8.498   -5.655  1.000 14.321 0 216 THR A CB  1 ? 
ATOM   1470 O OG1 . THR A 1 216 ? -5.232  8.212   -6.210  1.000 15.723 0 216 THR A OG1 1 ? 
ATOM   1471 C CG2 . THR A 1 216 ? -6.473  8.639   -4.149  1.000 13.579 0 216 THR A CG2 1 ? 
ATOM   1472 N N   . ASN A 1 217 ? -8.339  8.266   -8.111  1.000 16.761 0 217 ASN A N   1 ? 
ATOM   1473 C CA  . ASN A 1 217 ? -8.293  8.513   -9.530  1.000 17.796 0 217 ASN A CA  1 ? 
ATOM   1474 C C   . ASN A 1 217 ? -6.876  8.966   -9.877  1.000 14.930 0 217 ASN A C   1 ? 
ATOM   1475 O O   . ASN A 1 217 ? -6.214  9.629   -9.081  1.000 18.261 0 217 ASN A O   1 ? 
ATOM   1476 C CB  . ASN A 1 217 ? -9.234  9.652   -9.947  1.000 20.882 0 217 ASN A CB  1 ? 
ATOM   1477 C CG  . ASN A 1 217 ? -10.704 9.371   -9.694  1.000 29.024 0 217 ASN A CG  1 ? 
ATOM   1478 O OD1 . ASN A 1 217 ? -11.094 8.231   -9.442  1.000 29.821 0 217 ASN A OD1 1 ? 
ATOM   1479 N ND2 . ASN A 1 217 ? -11.515 10.415  -9.773  1.000 33.053 0 217 ASN A ND2 1 ? 
ATOM   1480 N N   . TRP A 1 218 ? -6.460  8.678   -11.097 1.000 15.092 0 218 TRP A N   1 ? 
ATOM   1481 C CA  . TRP A 1 218 ? -5.201  9.191   -11.588 1.000 14.439 0 218 TRP A CA  1 ? 
ATOM   1482 C C   . TRP A 1 218 ? -5.213  10.723  -11.582 1.000 16.206 0 218 TRP A C   1 ? 
ATOM   1483 O O   . TRP A 1 218 ? -6.224  11.356  -11.964 1.000 17.035 0 218 TRP A O   1 ? 
ATOM   1484 C CB  . TRP A 1 218 ? -4.941  8.671   -13.001 1.000 14.857 0 218 TRP A CB  1 ? 
ATOM   1485 C CG  . TRP A 1 218 ? -4.534  7.221   -13.069 1.000 14.310 0 218 TRP A CG  1 ? 
ATOM   1486 C CD1 . TRP A 1 218 ? -5.333  6.132   -13.273 1.000 14.618 0 218 TRP A CD1 1 ? 
ATOM   1487 C CD2 . TRP A 1 218 ? -3.188  6.732   -12.953 1.000 14.684 0 218 TRP A CD2 1 ? 
ATOM   1488 N NE1 . TRP A 1 218 ? -4.564  5.006   -13.305 1.000 16.978 0 218 TRP A NE1 1 ? 
ATOM   1489 C CE2 . TRP A 1 218 ? -3.248  5.325   -13.103 1.000 15.717 0 218 TRP A CE2 1 ? 
ATOM   1490 C CE3 . TRP A 1 218 ? -1.950  7.328   -12.745 1.000 15.241 0 218 TRP A CE3 1 ? 
ATOM   1491 C CZ2 . TRP A 1 218 ? -2.104  4.544   -13.066 1.000 14.624 0 218 TRP A CZ2 1 ? 
ATOM   1492 C CZ3 . TRP A 1 218 ? -0.824  6.553   -12.680 1.000 15.476 0 218 TRP A CZ3 1 ? 
ATOM   1493 C CH2 . TRP A 1 218 ? -0.896  5.173   -12.869 1.000 16.612 0 218 TRP A CH2 1 ? 
ATOM   1494 N N   . GLN A 1 219 ? -4.075  11.301  -11.181 1.000 15.105 0 219 GLN A N   1 ? 
ATOM   1495 C CA  . GLN A 1 219 ? -3.874  12.733  -11.080 1.000 15.327 0 219 GLN A CA  1 ? 
ATOM   1496 C C   . GLN A 1 219 ? -2.624  13.119  -11.851 1.000 13.991 0 219 GLN A C   1 ? 
ATOM   1497 O O   . GLN A 1 219 ? -1.632  12.381  -11.827 1.000 13.122 0 219 GLN A O   1 ? 
ATOM   1498 C CB  . GLN A 1 219 ? -3.749  13.084  -9.599  1.000 20.346 0 219 GLN A CB  1 ? 
ATOM   1499 C CG  . GLN A 1 219 ? -5.107  13.088  -8.915  1.000 29.329 0 219 GLN A CG  1 ? 
ATOM   1500 C CD  . GLN A 1 219 ? -5.560  14.509  -8.673  1.000 36.495 0 219 GLN A CD  1 ? 
ATOM   1501 O OE1 . GLN A 1 219 ? -5.343  15.407  -9.491  1.000 38.625 0 219 GLN A OE1 1 ? 
ATOM   1502 N NE2 . GLN A 1 219 ? -6.039  14.753  -7.466  1.000 40.911 0 219 GLN A NE2 1 ? 
ATOM   1503 N N   . SER A 1 220 ? -2.695  14.222  -12.600 1.000 13.045 0 220 SER A N   1 ? 
ATOM   1504 C CA  . SER A 1 220 ? -1.620  14.649  -13.449 1.000 12.428 0 220 SER A CA  1 ? 
ATOM   1505 C C   . SER A 1 220 ? -0.646  15.567  -12.706 1.000 13.314 0 220 SER A C   1 ? 
ATOM   1506 O O   . SER A 1 220 ? -1.095  16.474  -11.987 1.000 15.016 0 220 SER A O   1 ? 
ATOM   1507 C CB  . SER A 1 220 ? -2.144  15.378  -14.649 1.000 13.466 0 220 SER A CB  1 ? 
ATOM   1508 O OG  . SER A 1 220 ? -1.047  15.875  -15.427 1.000 13.751 0 220 SER A OG  1 ? 
ATOM   1509 N N   . LEU A 1 221 ? 0.664   15.397  -12.953 1.000 12.493 0 221 LEU A N   1 ? 
ATOM   1510 C CA  . LEU A 1 221 ? 1.666   16.382  -12.584 1.000 12.658 0 221 LEU A CA  1 ? 
ATOM   1511 C C   . LEU A 1 221 ? 2.297   17.004  -13.829 1.000 11.802 0 221 LEU A C   1 ? 
ATOM   1512 O O   . LEU A 1 221 ? 3.329   17.713  -13.729 1.000 12.445 0 221 LEU A O   1 ? 
ATOM   1513 C CB  . LEU A 1 221 ? 2.728   15.656  -11.742 1.000 13.729 0 221 LEU A CB  1 ? 
ATOM   1514 C CG  . LEU A 1 221 ? 2.315   15.274  -10.322 1.000 14.299 0 221 LEU A CG  1 ? 
ATOM   1515 C CD1 . LEU A 1 221 ? 3.354   14.409  -9.643  1.000 14.628 0 221 LEU A CD1 1 ? 
ATOM   1516 C CD2 . LEU A 1 221 ? 2.095   16.540  -9.563  1.000 15.497 0 221 LEU A CD2 1 ? 
ATOM   1517 N N   . SER A 1 222 ? 1.649   16.828  -14.978 1.000 12.625 0 222 SER A N   1 ? 
ATOM   1518 C CA  . SER A 1 222 ? 2.055   17.508  -16.195 1.000 12.359 0 222 SER A CA  1 ? 
ATOM   1519 C C   . SER A 1 222 ? 3.493   17.128  -16.568 1.000 14.272 0 222 SER A C   1 ? 
ATOM   1520 O O   . SER A 1 222 ? 3.958   16.042  -16.227 1.000 12.682 0 222 SER A O   1 ? 
ATOM   1521 C CB  . SER A 1 222 ? 1.899   19.032  -16.076 1.000 12.698 0 222 SER A CB  1 ? 
ATOM   1522 O OG  . SER A 1 222 ? 1.960   19.666  -17.355 1.000 13.954 0 222 SER A OG  1 ? 
ATOM   1523 N N   . GLY A 1 223 ? 4.172   18.029  -17.276 1.000 12.976 0 223 GLY A N   1 ? 
ATOM   1524 C CA  . GLY A 1 223 ? 5.525   17.803  -17.755 1.000 12.049 0 223 GLY A CA  1 ? 
ATOM   1525 C C   . GLY A 1 223 ? 5.554   17.127  -19.136 1.000 11.405 0 223 GLY A C   1 ? 
ATOM   1526 O O   . GLY A 1 223 ? 4.537   16.582  -19.604 1.000 12.654 0 223 GLY A O   1 ? 
ATOM   1527 N N   . VAL A 1 224 ? 6.738   17.154  -19.731 1.000 11.656 0 224 VAL A N   1 ? 
ATOM   1528 C CA  . VAL A 1 224 ? 7.071   16.360  -20.891 1.000 12.650 0 224 VAL A CA  1 ? 
ATOM   1529 C C   . VAL A 1 224 ? 8.286   15.549  -20.485 1.000 12.553 0 224 VAL A C   1 ? 
ATOM   1530 O O   . VAL A 1 224 ? 9.354   16.115  -20.263 1.000 12.944 0 224 VAL A O   1 ? 
ATOM   1531 C CB  . VAL A 1 224 ? 7.383   17.198  -22.148 1.000 14.846 0 224 VAL A CB  1 ? 
ATOM   1532 C CG1 . VAL A 1 224 ? 7.754   16.322  -23.332 1.000 14.419 0 224 VAL A CG1 1 ? 
ATOM   1533 C CG2 . VAL A 1 224 ? 6.232   18.142  -22.481 1.000 17.125 0 224 VAL A CG2 1 ? 
ATOM   1534 N N   . ILE A 1 225 ? 8.118   14.235  -20.363 1.000 12.912 0 225 ILE A N   1 ? 
ATOM   1535 C CA  . ILE A 1 225 ? 9.287   13.481  -19.936 1.000 13.747 0 225 ILE A CA  1 ? 
ATOM   1536 C C   . ILE A 1 225 ? 9.652   12.424  -20.972 1.000 13.415 0 225 ILE A C   1 ? 
ATOM   1537 O O   . ILE A 1 225 ? 8.807   11.869  -21.675 1.000 12.767 0 225 ILE A O   1 ? 
ATOM   1538 C CB  . ILE A 1 225 ? 9.139   12.946  -18.507 1.000 16.682 0 225 ILE A CB  1 ? 
ATOM   1539 C CG1 . ILE A 1 225 ? 7.984   11.964  -18.440 1.000 16.969 0 225 ILE A CG1 1 ? 
ATOM   1540 C CG2 . ILE A 1 225 ? 9.043   14.039  -17.444 1.000 16.882 0 225 ILE A CG2 1 ? 
ATOM   1541 C CD1 . ILE A 1 225 ? 7.981   11.090  -17.194 1.000 18.507 0 225 ILE A CD1 1 ? 
ATOM   1542 N N   . THR A 1 226 ? 10.968  12.229  -21.069 1.000 12.106 0 226 THR A N   1 ? 
ATOM   1543 C CA  . THR A 1 226 ? 11.578  11.406  -22.091 1.000 12.600 0 226 THR A CA  1 ? 
ATOM   1544 C C   . THR A 1 226 ? 12.450  10.282  -21.529 1.000 13.263 0 226 THR A C   1 ? 
ATOM   1545 O O   . THR A 1 226 ? 13.302  9.737   -22.239 1.000 14.283 0 226 THR A O   1 ? 
ATOM   1546 C CB  . THR A 1 226 ? 12.410  12.280  -23.034 1.000 13.838 0 226 THR A CB  1 ? 
ATOM   1547 O OG1 . THR A 1 226 ? 13.503  12.807  -22.289 1.000 14.724 0 226 THR A OG1 1 ? 
ATOM   1548 C CG2 . THR A 1 226 ? 11.624  13.429  -23.637 1.000 14.666 0 226 THR A CG2 1 ? 
ATOM   1549 N N   . SER A 1 227 ? 12.242  9.943   -20.253 1.000 13.370 0 227 SER A N   1 ? 
ATOM   1550 C CA  . SER A 1 227 ? 12.829  8.761   -19.641 1.000 13.311 0 227 SER A CA  1 ? 
ATOM   1551 C C   . SER A 1 227 ? 11.779  8.095   -18.781 1.000 14.028 0 227 SER A C   1 ? 
ATOM   1552 O O   . SER A 1 227 ? 10.773  8.699   -18.460 1.000 14.309 0 227 SER A O   1 ? 
ATOM   1553 C CB  . SER A 1 227 ? 14.050  9.077   -18.830 1.000 13.431 0 227 SER A CB  1 ? 
ATOM   1554 O OG  . SER A 1 227 ? 13.713  9.698   -17.609 1.000 12.347 0 227 SER A OG  1 ? 
ATOM   1555 N N   . ASN A 1 228 ? 12.089  6.906   -18.268 1.000 14.060 0 228 ASN A N   1 ? 
ATOM   1556 C CA  . ASN A 1 228 ? 11.299  6.429   -17.152 1.000 14.682 0 228 ASN A CA  1 ? 
ATOM   1557 C C   . ASN A 1 228 ? 11.436  7.427   -16.021 1.000 12.831 0 228 ASN A C   1 ? 
ATOM   1558 O O   . ASN A 1 228 ? 12.540  7.903   -15.759 1.000 13.257 0 228 ASN A O   1 ? 
ATOM   1559 C CB  . ASN A 1 228 ? 11.821  5.104   -16.607 1.000 14.839 0 228 ASN A CB  1 ? 
ATOM   1560 C CG  . ASN A 1 228 ? 11.340  3.877   -17.314 1.000 18.750 0 228 ASN A CG  1 ? 
ATOM   1561 O OD1 . ASN A 1 228 ? 10.336  3.863   -18.042 1.000 18.416 0 228 ASN A OD1 1 ? 
ATOM   1562 N ND2 . ASN A 1 228 ? 12.049  2.794   -17.003 1.000 22.913 0 228 ASN A ND2 1 ? 
ATOM   1563 N N   . PRO A 1 229 ? 10.352  7.708   -15.295 1.000 12.464 0 229 PRO A N   1 ? 
ATOM   1564 C CA  . PRO A 1 229 ? 10.465  8.458   -14.038 1.000 12.693 0 229 PRO A CA  1 ? 
ATOM   1565 C C   . PRO A 1 229 ? 10.876  7.559   -12.884 1.000 12.279 0 229 PRO A C   1 ? 
ATOM   1566 O O   . PRO A 1 229 ? 10.629  6.346   -12.924 1.000 12.307 0 229 PRO A O   1 ? 
ATOM   1567 C CB  . PRO A 1 229 ? 9.025   8.976   -13.880 1.000 12.462 0 229 PRO A CB  1 ? 
ATOM   1568 C CG  . PRO A 1 229 ? 8.177   7.817   -14.434 1.000 13.536 0 229 PRO A CG  1 ? 
ATOM   1569 C CD  . PRO A 1 229 ? 8.982   7.302   -15.618 1.000 13.049 0 229 PRO A CD  1 ? 
ATOM   1570 N N   . VAL A 1 230 ? 11.511  8.154   -11.891 1.000 11.630 0 230 VAL A N   1 ? 
ATOM   1571 C CA  A VAL A 1 230 ? 11.901  7.424   -10.684 0.800 12.504 0 230 VAL A CA  1 ? 
ATOM   1572 C CA  B VAL A 1 230 ? 11.851  7.410   -10.691 0.200 12.126 0 230 VAL A CA  1 ? 
ATOM   1573 C C   . VAL A 1 230 ? 11.480  8.250   -9.480  1.000 12.091 0 230 VAL A C   1 ? 
ATOM   1574 O O   . VAL A 1 230 ? 11.836  9.434   -9.384  1.000 12.830 0 230 VAL A O   1 ? 
ATOM   1575 C CB  A VAL A 1 230 ? 13.403  7.040   -10.646 0.800 13.328 0 230 VAL A CB  1 ? 
ATOM   1576 C CB  B VAL A 1 230 ? 13.324  6.957   -10.687 0.200 12.373 0 230 VAL A CB  1 ? 
ATOM   1577 C CG1 A VAL A 1 230 ? 14.314  8.232   -10.593 0.800 14.241 0 230 VAL A CG1 1 ? 
ATOM   1578 C CG1 B VAL A 1 230 ? 13.484  5.633   -11.415 0.200 12.385 0 230 VAL A CG1 1 ? 
ATOM   1579 C CG2 A VAL A 1 230 ? 13.716  6.128   -9.470  0.800 12.886 0 230 VAL A CG2 1 ? 
ATOM   1580 C CG2 B VAL A 1 230 ? 14.249  8.010   -11.264 0.200 12.377 0 230 VAL A CG2 1 ? 
ATOM   1581 N N   . VAL A 1 231 ? 10.727  7.619   -8.551  1.000 11.113 0 231 VAL A N   1 ? 
ATOM   1582 C CA  . VAL A 1 231 ? 10.306  8.277   -7.341  1.000 11.540 0 231 VAL A CA  1 ? 
ATOM   1583 C C   . VAL A 1 231 ? 11.138  7.800   -6.150  1.000 11.656 0 231 VAL A C   1 ? 
ATOM   1584 O O   . VAL A 1 231 ? 11.555  6.637   -6.078  1.000 12.993 0 231 VAL A O   1 ? 
ATOM   1585 C CB  . VAL A 1 231 ? 8.799   8.080   -7.110  1.000 11.642 0 231 VAL A CB  1 ? 
ATOM   1586 C CG1 . VAL A 1 231 ? 8.419   6.608   -6.891  1.000 12.375 0 231 VAL A CG1 1 ? 
ATOM   1587 C CG2 . VAL A 1 231 ? 8.363   8.945   -5.928  1.000 12.686 0 231 VAL A CG2 1 ? 
ATOM   1588 N N   . ILE A 1 232 ? 11.296  8.686   -5.177  1.000 11.671 0 232 ILE A N   1 ? 
ATOM   1589 C CA  . ILE A 1 232 ? 11.962  8.346   -3.928  1.000 12.425 0 232 ILE A CA  1 ? 
ATOM   1590 C C   . ILE A 1 232 ? 11.366  9.238   -2.858  1.000 12.151 0 232 ILE A C   1 ? 
ATOM   1591 O O   . ILE A 1 232 ? 10.700  10.227  -3.149  1.000 12.774 0 232 ILE A O   1 ? 
ATOM   1592 C CB  . ILE A 1 232 ? 13.490  8.540   -4.057  1.000 13.393 0 232 ILE A CB  1 ? 
ATOM   1593 C CG1 . ILE A 1 232 ? 14.225  7.966   -2.851  1.000 14.975 0 232 ILE A CG1 1 ? 
ATOM   1594 C CG2 . ILE A 1 232 ? 13.819  10.012  -4.260  1.000 12.864 0 232 ILE A CG2 1 ? 
ATOM   1595 C CD1 . ILE A 1 232 ? 15.682  7.728   -3.053  1.000 15.152 0 232 ILE A CD1 1 ? 
ATOM   1596 N N   . SER A 1 233 ? 11.586  8.906   -1.580  1.000 14.251 0 233 SER A N   1 ? 
ATOM   1597 C CA  . SER A 1 233 ? 11.203  9.780   -0.485  1.000 15.295 0 233 SER A CA  1 ? 
ATOM   1598 C C   . SER A 1 233 ? 12.417  10.491  0.103   1.000 15.349 0 233 SER A C   1 ? 
ATOM   1599 O O   . SER A 1 233 ? 13.454  9.878   0.301   1.000 17.199 0 233 SER A O   1 ? 
ATOM   1600 C CB  . SER A 1 233 ? 10.572  8.982   0.621   1.000 17.209 0 233 SER A CB  1 ? 
ATOM   1601 O OG  . SER A 1 233 ? 10.071  9.863   1.608   1.000 18.461 0 233 SER A OG  1 ? 
ATOM   1602 N N   . ASN A 1 234 ? 12.276  11.790  0.343   1.000 15.287 0 234 ASN A N   1 ? 
ATOM   1603 C CA  . ASN A 1 234 ? 13.212  12.503  1.199   1.000 15.738 0 234 ASN A CA  1 ? 
ATOM   1604 C C   . ASN A 1 234 ? 13.131  11.936  2.620   1.000 17.779 0 234 ASN A C   1 ? 
ATOM   1605 O O   . ASN A 1 234 ? 12.172  11.264  2.956   1.000 19.614 0 234 ASN A O   1 ? 
ATOM   1606 C CB  . ASN A 1 234 ? 12.845  13.989  1.207   1.000 16.503 0 234 ASN A CB  1 ? 
ATOM   1607 C CG  . ASN A 1 234 ? 13.274  14.706  -0.055  1.000 14.521 0 234 ASN A CG  1 ? 
ATOM   1608 O OD1 . ASN A 1 234 ? 14.438  15.078  -0.201  1.000 15.299 0 234 ASN A OD1 1 ? 
ATOM   1609 N ND2 . ASN A 1 234 ? 12.354  14.855  -1.013  1.000 14.160 0 234 ASN A ND2 1 ? 
ATOM   1610 N N   . SER A 1 235 ? 14.164  12.206  3.424   1.000 19.495 0 235 SER A N   1 ? 
ATOM   1611 C CA  . SER A 1 235 ? 14.199  11.651  4.771   1.000 21.307 0 235 SER A CA  1 ? 
ATOM   1612 C C   . SER A 1 235 ? 12.979  12.058  5.591   1.000 22.529 0 235 SER A C   1 ? 
ATOM   1613 O O   . SER A 1 235 ? 12.634  11.336  6.512   1.000 26.533 0 235 SER A O   1 ? 
ATOM   1614 C CB  . SER A 1 235 ? 15.454  12.010  5.453   1.000 22.308 0 235 SER A CB  1 ? 
ATOM   1615 O OG  . SER A 1 235 ? 15.604  13.400  5.499   1.000 27.973 0 235 SER A OG  1 ? 
ATOM   1616 N N   . ASP A 1 236 ? 12.326  13.181  5.282   1.000 19.579 0 236 ASP A N   1 ? 
ATOM   1617 C CA  . ASP A 1 236 ? 11.189  13.655  6.062   1.000 20.582 0 236 ASP A CA  1 ? 
ATOM   1618 C C   . ASP A 1 236 ? 9.836   13.205  5.507   1.000 21.461 0 236 ASP A C   1 ? 
ATOM   1619 O O   . ASP A 1 236 ? 8.782   13.557  6.029   1.000 22.517 0 236 ASP A O   1 ? 
ATOM   1620 C CB  . ASP A 1 236 ? 11.146  15.177  6.159   1.000 22.420 0 236 ASP A CB  1 ? 
ATOM   1621 C CG  . ASP A 1 236 ? 10.908  15.892  4.835   1.000 24.760 0 236 ASP A CG  1 ? 
ATOM   1622 O OD1 . ASP A 1 236 ? 10.876  15.205  3.791   1.000 21.783 0 236 ASP A OD1 1 ? 
ATOM   1623 O OD2 . ASP A 1 236 ? 10.736  17.130  4.860   1.000 28.280 0 236 ASP A OD2 1 ? 
ATOM   1624 N N   . GLY A 1 237 ? 9.834   12.361  4.473   1.000 19.668 0 237 GLY A N   1 ? 
ATOM   1625 C CA  . GLY A 1 237 ? 8.589   11.807  3.977   1.000 18.682 0 237 GLY A CA  1 ? 
ATOM   1626 C C   . GLY A 1 237 ? 8.038   12.438  2.696   1.000 20.252 0 237 GLY A C   1 ? 
ATOM   1627 O O   . GLY A 1 237 ? 7.057   11.937  2.160   1.000 22.678 0 237 GLY A O   1 ? 
ATOM   1628 N N   . ARG A 1 238 ? 8.619   13.547  2.226   1.000 16.700 0 238 ARG A N   1 ? 
ATOM   1629 C CA  . ARG A 1 238 ? 8.212   14.235  1.015   1.000 16.030 0 238 ARG A CA  1 ? 
ATOM   1630 C C   . ARG A 1 238 ? 8.687   13.421  -0.184  1.000 15.561 0 238 ARG A C   1 ? 
ATOM   1631 O O   . ARG A 1 238 ? 9.879   13.183  -0.359  1.000 14.391 0 238 ARG A O   1 ? 
ATOM   1632 C CB  . ARG A 1 238 ? 8.825   15.638  0.957   1.000 16.484 0 238 ARG A CB  1 ? 
ATOM   1633 C CG  . ARG A 1 238 ? 8.243   16.661  1.930   1.000 16.374 0 238 ARG A CG  1 ? 
ATOM   1634 C CD  . ARG A 1 238 ? 8.942   18.009  1.854   1.000 18.828 0 238 ARG A CD  1 ? 
ATOM   1635 N NE  . ARG A 1 238 ? 10.341  17.908  2.247   1.000 19.632 0 238 ARG A NE  1 ? 
ATOM   1636 C CZ  . ARG A 1 238 ? 11.361  18.019  1.417   1.000 21.259 0 238 ARG A CZ  1 ? 
ATOM   1637 N NH1 . ARG A 1 238 ? 11.192  18.552  0.235   1.000 26.068 0 238 ARG A NH1 1 ? 
ATOM   1638 N NH2 . ARG A 1 238 ? 12.546  17.568  1.771   1.000 21.362 0 238 ARG A NH2 1 ? 
ATOM   1639 N N   . LEU A 1 239 ? 7.761   12.979  -1.020  1.000 14.608 0 239 LEU A N   1 ? 
ATOM   1640 C CA  . LEU A 1 239 ? 8.171   12.306  -2.258  1.000 14.585 0 239 LEU A CA  1 ? 
ATOM   1641 C C   . LEU A 1 239 ? 8.714   13.282  -3.292  1.000 13.037 0 239 LEU A C   1 ? 
ATOM   1642 O O   . LEU A 1 239 ? 8.437   14.498  -3.298  1.000 13.127 0 239 LEU A O   1 ? 
ATOM   1643 C CB  . LEU A 1 239 ? 6.960   11.579  -2.865  1.000 13.953 0 239 LEU A CB  1 ? 
ATOM   1644 C CG  . LEU A 1 239 ? 6.317   10.498  -2.004  1.000 14.812 0 239 LEU A CG  1 ? 
ATOM   1645 C CD1 . LEU A 1 239 ? 5.176   9.813   -2.772  1.000 16.044 0 239 LEU A CD1 1 ? 
ATOM   1646 C CD2 . LEU A 1 239 ? 7.318   9.461   -1.592  1.000 15.971 0 239 LEU A CD2 1 ? 
ATOM   1647 N N   . GLU A 1 240 ? 9.560   12.717  -4.147  1.000 12.410 0 240 GLU A N   1 ? 
ATOM   1648 C CA  . GLU A 1 240 ? 10.251  13.488  -5.173  1.000 12.560 0 240 GLU A CA  1 ? 
ATOM   1649 C C   . GLU A 1 240 ? 10.434  12.575  -6.362  1.000 10.859 0 240 GLU A C   1 ? 
ATOM   1650 O O   . GLU A 1 240 ? 10.891  11.442  -6.203  1.000 12.194 0 240 GLU A O   1 ? 
ATOM   1651 C CB  . GLU A 1 240 ? 11.573  14.013  -4.589  1.000 13.035 0 240 GLU A CB  1 ? 
ATOM   1652 C CG  . GLU A 1 240 ? 12.314  14.983  -5.485  1.000 13.733 0 240 GLU A CG  1 ? 
ATOM   1653 C CD  . GLU A 1 240 ? 13.167  16.018  -4.777  1.000 14.288 0 240 GLU A CD  1 ? 
ATOM   1654 O OE1 . GLU A 1 240 ? 13.104  16.112  -3.500  1.000 14.177 0 240 GLU A OE1 1 ? 
ATOM   1655 O OE2 . GLU A 1 240 ? 13.893  16.743  -5.485  1.000 14.685 0 240 GLU A OE2 1 ? 
ATOM   1656 N N   . VAL A 1 241 ? 10.153  13.102  -7.563  1.000 10.734 0 241 VAL A N   1 ? 
ATOM   1657 C CA  . VAL A 1 241 ? 10.297  12.336  -8.795  1.000 10.720 0 241 VAL A CA  1 ? 
ATOM   1658 C C   . VAL A 1 241 ? 11.308  12.983  -9.737  1.000 10.889 0 241 VAL A C   1 ? 
ATOM   1659 O O   . VAL A 1 241 ? 11.360  14.185  -9.849  1.000 11.976 0 241 VAL A O   1 ? 
ATOM   1660 C CB  . VAL A 1 241 ? 8.948   12.174  -9.523  1.000 11.773 0 241 VAL A CB  1 ? 
ATOM   1661 C CG1 . VAL A 1 241 ? 9.065   11.322  -10.766 1.000 13.296 0 241 VAL A CG1 1 ? 
ATOM   1662 C CG2 . VAL A 1 241 ? 7.871   11.634  -8.618  1.000 12.111 0 241 VAL A CG2 1 ? 
ATOM   1663 N N   . PHE A 1 242 ? 12.160  12.160  -10.333 1.000 10.628 0 242 PHE A N   1 ? 
ATOM   1664 C CA  . PHE A 1 242 ? 13.181  12.555  -11.286 1.000 10.813 0 242 PHE A CA  1 ? 
ATOM   1665 C C   . PHE A 1 242 ? 12.879  11.962  -12.666 1.000 10.776 0 242 PHE A C   1 ? 
ATOM   1666 O O   . PHE A 1 242 ? 12.472  10.812  -12.765 1.000 10.289 0 242 PHE A O   1 ? 
ATOM   1667 C CB  . PHE A 1 242 ? 14.553  12.079  -10.808 1.000 10.924 0 242 PHE A CB  1 ? 
ATOM   1668 C CG  . PHE A 1 242 ? 14.890  12.677  -9.476  1.000 11.069 0 242 PHE A CG  1 ? 
ATOM   1669 C CD1 . PHE A 1 242 ? 15.603  13.859  -9.445  1.000 10.779 0 242 PHE A CD1 1 ? 
ATOM   1670 C CD2 . PHE A 1 242 ? 14.543  12.060  -8.283  1.000 11.716 0 242 PHE A CD2 1 ? 
ATOM   1671 C CE1 . PHE A 1 242 ? 15.876  14.468  -8.227  1.000 11.635 0 242 PHE A CE1 1 ? 
ATOM   1672 C CE2 . PHE A 1 242 ? 14.790  12.694  -7.072  1.000 13.501 0 242 PHE A CE2 1 ? 
ATOM   1673 C CZ  . PHE A 1 242 ? 15.490  13.868  -7.049  1.000 12.038 0 242 PHE A CZ  1 ? 
ATOM   1674 N N   . ALA A 1 243 ? 13.140  12.733  -13.718 1.000 11.358 0 243 ALA A N   1 ? 
ATOM   1675 C CA  . ALA A 1 243 ? 13.023  12.209  -15.067 1.000 11.309 0 243 ALA A CA  1 ? 
ATOM   1676 C C   . ALA A 1 243 ? 13.799  13.090  -16.026 1.000 11.321 0 243 ALA A C   1 ? 
ATOM   1677 O O   . ALA A 1 243 ? 14.018  14.276  -15.757 1.000 12.858 0 243 ALA A O   1 ? 
ATOM   1678 C CB  . ALA A 1 243 ? 11.573  12.184  -15.480 1.000 11.710 0 243 ALA A CB  1 ? 
ATOM   1679 N N   . ARG A 1 244 ? 14.175  12.532  -17.185 1.000 11.288 0 244 ARG A N   1 ? 
ATOM   1680 C CA  . ARG A 1 244 ? 14.714  13.360  -18.246 1.000 11.381 0 244 ARG A CA  1 ? 
ATOM   1681 C C   . ARG A 1 244 ? 13.609  14.170  -18.922 1.000 11.258 0 244 ARG A C   1 ? 
ATOM   1682 O O   . ARG A 1 244 ? 12.480  13.687  -19.076 1.000 11.378 0 244 ARG A O   1 ? 
ATOM   1683 C CB  . ARG A 1 244 ? 15.375  12.506  -19.315 1.000 12.087 0 244 ARG A CB  1 ? 
ATOM   1684 C CG  . ARG A 1 244 ? 16.198  13.297  -20.329 1.000 11.521 0 244 ARG A CG  1 ? 
ATOM   1685 C CD  . ARG A 1 244 ? 16.997  12.364  -21.205 1.000 12.141 0 244 ARG A CD  1 ? 
ATOM   1686 N NE  . ARG A 1 244 ? 16.186  11.541  -22.088 1.000 13.134 0 244 ARG A NE  1 ? 
ATOM   1687 C CZ  . ARG A 1 244 ? 16.676  10.671  -22.941 1.000 17.095 0 244 ARG A CZ  1 ? 
ATOM   1688 N NH1 . ARG A 1 244 ? 17.989  10.496  -23.032 1.000 18.515 0 244 ARG A NH1 1 ? 
ATOM   1689 N NH2 . ARG A 1 244 ? 15.845  9.953   -23.669 1.000 18.028 0 244 ARG A NH2 1 ? 
ATOM   1690 N N   . GLY A 1 245 ? 13.949  15.420  -19.255 1.000 11.735 0 245 GLY A N   1 ? 
ATOM   1691 C CA  . GLY A 1 245 ? 12.981  16.302  -19.885 1.000 12.444 0 245 GLY A CA  1 ? 
ATOM   1692 C C   . GLY A 1 245 ? 13.209  16.372  -21.394 1.000 12.653 0 245 GLY A C   1 ? 
ATOM   1693 O O   . GLY A 1 245 ? 14.092  15.709  -21.917 1.000 13.469 0 245 GLY A O   1 ? 
ATOM   1694 N N   . SER A 1 246 ? 12.422  17.227  -22.067 1.000 13.141 0 246 SER A N   1 ? 
ATOM   1695 C CA  . SER A 1 246 ? 12.458  17.262  -23.516 1.000 14.399 0 246 SER A CA  1 ? 
ATOM   1696 C C   . SER A 1 246 ? 13.742  17.902  -24.037 1.000 15.935 0 246 SER A C   1 ? 
ATOM   1697 O O   . SER A 1 246 ? 14.036  17.796  -25.244 1.000 16.263 0 246 SER A O   1 ? 
ATOM   1698 C CB  . SER A 1 246 ? 11.217  17.989  -24.007 1.000 17.002 0 246 SER A CB  1 ? 
ATOM   1699 O OG  . SER A 1 246 ? 11.235  19.336  -23.581 1.000 17.989 0 246 SER A OG  1 ? 
ATOM   1700 N N   . ASP A 1 247 ? 14.487  18.590  -23.156 1.000 13.787 0 247 ASP A N   1 ? 
ATOM   1701 C CA  . ASP A 1 247 ? 15.757  19.249  -23.471 1.000 13.827 0 247 ASP A CA  1 ? 
ATOM   1702 C C   . ASP A 1 247 ? 16.930  18.364  -23.018 1.000 13.943 0 247 ASP A C   1 ? 
ATOM   1703 O O   . ASP A 1 247 ? 18.082  18.797  -23.085 1.000 16.202 0 247 ASP A O   1 ? 
ATOM   1704 C CB  . ASP A 1 247 ? 15.797  20.637  -22.834 1.000 13.486 0 247 ASP A CB  1 ? 
ATOM   1705 C CG  . ASP A 1 247 ? 15.680  20.607  -21.313 1.000 16.027 0 247 ASP A CG  1 ? 
ATOM   1706 O OD1 . ASP A 1 247 ? 15.482  19.509  -20.764 1.000 14.401 0 247 ASP A OD1 1 ? 
ATOM   1707 O OD2 . ASP A 1 247 ? 15.708  21.709  -20.681 1.000 18.400 0 247 ASP A OD2 1 ? 
ATOM   1708 N N   . ASN A 1 248 ? 16.628  17.120  -22.624 1.000 14.268 0 248 ASN A N   1 ? 
ATOM   1709 C CA  . ASN A 1 248 ? 17.590  16.107  -22.165 1.000 13.082 0 248 ASN A CA  1 ? 
ATOM   1710 C C   . ASN A 1 248 ? 18.250  16.442  -20.834 1.000 12.134 0 248 ASN A C   1 ? 
ATOM   1711 O O   . ASN A 1 248 ? 19.188  15.749  -20.418 1.000 12.379 0 248 ASN A O   1 ? 
ATOM   1712 C CB  . ASN A 1 248 ? 18.633  15.780  -23.229 1.000 15.035 0 248 ASN A CB  1 ? 
ATOM   1713 C CG  . ASN A 1 248 ? 18.009  15.032  -24.369 1.000 17.809 0 248 ASN A CG  1 ? 
ATOM   1714 O OD1 . ASN A 1 248 ? 17.258  14.087  -24.150 1.000 21.316 0 248 ASN A OD1 1 ? 
ATOM   1715 N ND2 . ASN A 1 248 ? 18.282  15.501  -25.574 1.000 23.319 0 248 ASN A ND2 1 ? 
ATOM   1716 N N   . ALA A 1 249 ? 17.801  17.507  -20.177 1.000 12.425 0 249 ALA A N   1 ? 
ATOM   1717 C CA  . ALA A 1 249 ? 18.221  17.775  -18.809 1.000 12.460 0 249 ALA A CA  1 ? 
ATOM   1718 C C   . ALA A 1 249 ? 17.512  16.820  -17.857 1.000 11.681 0 249 ALA A C   1 ? 
ATOM   1719 O O   . ALA A 1 249 ? 16.480  16.233  -18.170 1.000 12.085 0 249 ALA A O   1 ? 
ATOM   1720 C CB  . ALA A 1 249 ? 17.963  19.220  -18.440 1.000 13.906 0 249 ALA A CB  1 ? 
ATOM   1721 N N   . LEU A 1 250 ? 18.072  16.746  -16.647 1.000 11.658 0 250 LEU A N   1 ? 
ATOM   1722 C CA  . LEU A 1 250 ? 17.354  16.144  -15.533 1.000 10.998 0 250 LEU A CA  1 ? 
ATOM   1723 C C   . LEU A 1 250 ? 16.349  17.132  -14.965 1.000 11.524 0 250 LEU A C   1 ? 
ATOM   1724 O O   . LEU A 1 250 ? 16.767  18.228  -14.571 1.000 12.716 0 250 LEU A O   1 ? 
ATOM   1725 C CB  . LEU A 1 250 ? 18.373  15.774  -14.468 1.000 11.425 0 250 LEU A CB  1 ? 
ATOM   1726 C CG  . LEU A 1 250 ? 17.794  15.228  -13.176 1.000 12.606 0 250 LEU A CG  1 ? 
ATOM   1727 C CD1 . LEU A 1 250 ? 17.142  13.884  -13.414 1.000 13.262 0 250 LEU A CD1 1 ? 
ATOM   1728 C CD2 . LEU A 1 250 ? 18.848  15.125  -12.093 1.000 12.528 0 250 LEU A CD2 1 ? 
ATOM   1729 N N   . TRP A 1 251 ? 15.089  16.730  -14.851 1.000 11.519 0 251 TRP A N   1 ? 
ATOM   1730 C CA  . TRP A 1 251 ? 14.090  17.521  -14.171 1.000 11.438 0 251 TRP A CA  1 ? 
ATOM   1731 C C   . TRP A 1 251 ? 13.574  16.806  -12.927 1.000 10.217 0 251 TRP A C   1 ? 
ATOM   1732 O O   . TRP A 1 251 ? 13.735  15.610  -12.799 1.000 10.980 0 251 TRP A O   1 ? 
ATOM   1733 C CB  . TRP A 1 251 ? 12.962  17.865  -15.138 1.000 12.630 0 251 TRP A CB  1 ? 
ATOM   1734 C CG  . TRP A 1 251 ? 13.373  18.799  -16.243 1.000 11.939 0 251 TRP A CG  1 ? 
ATOM   1735 C CD1 . TRP A 1 251 ? 14.152  18.546  -17.344 1.000 12.236 0 251 TRP A CD1 1 ? 
ATOM   1736 C CD2 . TRP A 1 251 ? 12.892  20.145  -16.399 1.000 13.117 0 251 TRP A CD2 1 ? 
ATOM   1737 N NE1 . TRP A 1 251 ? 14.210  19.664  -18.145 1.000 12.388 0 251 TRP A NE1 1 ? 
ATOM   1738 C CE2 . TRP A 1 251 ? 13.470  20.657  -17.578 1.000 12.612 0 251 TRP A CE2 1 ? 
ATOM   1739 C CE3 . TRP A 1 251 ? 12.037  20.954  -15.642 1.000 14.133 0 251 TRP A CE3 1 ? 
ATOM   1740 C CZ2 . TRP A 1 251 ? 13.207  21.956  -18.024 1.000 14.394 0 251 TRP A CZ2 1 ? 
ATOM   1741 C CZ3 . TRP A 1 251 ? 11.765  22.240  -16.076 1.000 13.880 0 251 TRP A CZ3 1 ? 
ATOM   1742 C CH2 . TRP A 1 251 ? 12.296  22.701  -17.290 1.000 13.066 0 251 TRP A CH2 1 ? 
ATOM   1743 N N   . HIS A 1 252 ? 12.939  17.546  -12.017 1.000 11.492 0 252 HIS A N   1 ? 
ATOM   1744 C CA  . HIS A 1 252 ? 12.426  16.961  -10.805 1.000 11.071 0 252 HIS A CA  1 ? 
ATOM   1745 C C   . HIS A 1 252 ? 11.243  17.787  -10.324 1.000 11.207 0 252 HIS A C   1 ? 
ATOM   1746 O O   . HIS A 1 252 ? 11.023  18.933  -10.731 1.000 12.942 0 252 HIS A O   1 ? 
ATOM   1747 C CB  . HIS A 1 252 ? 13.476  16.770  -9.710  1.000 12.196 0 252 HIS A CB  1 ? 
ATOM   1748 C CG  . HIS A 1 252 ? 14.007  18.019  -9.082  1.000 12.536 0 252 HIS A CG  1 ? 
ATOM   1749 N ND1 . HIS A 1 252 ? 14.265  18.106  -7.717  1.000 13.649 0 252 HIS A ND1 1 ? 
ATOM   1750 C CD2 . HIS A 1 252 ? 14.330  19.218  -9.585  1.000 13.479 0 252 HIS A CD2 1 ? 
ATOM   1751 C CE1 . HIS A 1 252 ? 14.737  19.339  -7.450  1.000 13.013 0 252 HIS A CE1 1 ? 
ATOM   1752 N NE2 . HIS A 1 252 ? 14.829  20.022  -8.560  1.000 13.842 0 252 HIS A NE2 1 ? 
ATOM   1753 N N   . ILE A 1 253 ? 10.450  17.126  -9.480  1.000 11.300 0 253 ILE A N   1 ? 
ATOM   1754 C CA  . ILE A 1 253 ? 9.227   17.705  -8.943  1.000 10.617 0 253 ILE A CA  1 ? 
ATOM   1755 C C   . ILE A 1 253 ? 9.058   17.068  -7.571  1.000 12.461 0 253 ILE A C   1 ? 
ATOM   1756 O O   . ILE A 1 253 ? 9.422   15.894  -7.431  1.000 13.179 0 253 ILE A O   1 ? 
ATOM   1757 C CB  . ILE A 1 253 ? 8.051   17.443  -9.915  1.000 11.861 0 253 ILE A CB  1 ? 
ATOM   1758 C CG1 . ILE A 1 253 ? 6.784   18.177  -9.469  1.000 13.016 0 253 ILE A CG1 1 ? 
ATOM   1759 C CG2 . ILE A 1 253 ? 7.812   15.966  -10.107 1.000 13.057 0 253 ILE A CG2 1 ? 
ATOM   1760 C CD1 . ILE A 1 253 ? 5.715   18.236  -10.541 1.000 13.796 0 253 ILE A CD1 1 ? 
ATOM   1761 N N   . TRP A 1 254 ? 8.551   17.775  -6.562  1.000 11.827 0 254 TRP A N   1 ? 
ATOM   1762 C CA  . TRP A 1 254 ? 8.502   17.201  -5.229  1.000 12.748 0 254 TRP A CA  1 ? 
ATOM   1763 C C   . TRP A 1 254 ? 7.334   17.743  -4.431  1.000 12.506 0 254 TRP A C   1 ? 
ATOM   1764 O O   . TRP A 1 254 ? 6.767   18.779  -4.760  1.000 13.578 0 254 TRP A O   1 ? 
ATOM   1765 C CB  . TRP A 1 254 ? 9.826   17.382  -4.460  1.000 13.782 0 254 TRP A CB  1 ? 
ATOM   1766 C CG  . TRP A 1 254 ? 10.173  18.817  -4.147  1.000 15.868 0 254 TRP A CG  1 ? 
ATOM   1767 C CD1 . TRP A 1 254 ? 9.986   19.445  -2.951  1.000 16.526 0 254 TRP A CD1 1 ? 
ATOM   1768 C CD2 . TRP A 1 254 ? 10.826  19.783  -4.997  1.000 16.279 0 254 TRP A CD2 1 ? 
ATOM   1769 N NE1 . TRP A 1 254 ? 10.481  20.727  -2.995  1.000 16.985 0 254 TRP A NE1 1 ? 
ATOM   1770 C CE2 . TRP A 1 254 ? 10.991  20.966  -4.239  1.000 16.292 0 254 TRP A CE2 1 ? 
ATOM   1771 C CE3 . TRP A 1 254 ? 11.270  19.765  -6.310  1.000 14.696 0 254 TRP A CE3 1 ? 
ATOM   1772 C CZ2 . TRP A 1 254 ? 11.610  22.112  -4.756  1.000 16.255 0 254 TRP A CZ2 1 ? 
ATOM   1773 C CZ3 . TRP A 1 254 ? 11.853  20.896  -6.828  1.000 19.382 0 254 TRP A CZ3 1 ? 
ATOM   1774 C CH2 . TRP A 1 254 ? 11.991  22.054  -6.070  1.000 17.698 0 254 TRP A CH2 1 ? 
ATOM   1775 N N   . GLN A 1 255 ? 7.040   17.029  -3.342  1.000 13.643 0 255 GLN A N   1 ? 
ATOM   1776 C CA  . GLN A 1 255 ? 5.996   17.436  -2.412  1.000 13.994 0 255 GLN A CA  1 ? 
ATOM   1777 C C   . GLN A 1 255 ? 6.510   18.544  -1.506  1.000 14.753 0 255 GLN A C   1 ? 
ATOM   1778 O O   . GLN A 1 255 ? 7.637   18.489  -1.046  1.000 15.474 0 255 GLN A O   1 ? 
ATOM   1779 C CB  . GLN A 1 255 ? 5.516   16.247  -1.579  1.000 13.856 0 255 GLN A CB  1 ? 
ATOM   1780 C CG  . GLN A 1 255 ? 4.733   15.253  -2.420  1.000 13.424 0 255 GLN A CG  1 ? 
ATOM   1781 C CD  . GLN A 1 255 ? 4.227   14.092  -1.611  1.000 15.161 0 255 GLN A CD  1 ? 
ATOM   1782 O OE1 . GLN A 1 255 ? 4.926   13.455  -0.833  1.000 16.034 0 255 GLN A OE1 1 ? 
ATOM   1783 N NE2 . GLN A 1 255 ? 2.992   13.701  -1.846  1.000 16.709 0 255 GLN A NE2 1 ? 
ATOM   1784 N N   . VAL A 1 256 ? 5.601   19.470  -1.182  1.000 16.439 0 256 VAL A N   1 ? 
ATOM   1785 C CA  . VAL A 1 256 ? 5.978   20.639  -0.386  1.000 17.122 0 256 VAL A CA  1 ? 
ATOM   1786 C C   . VAL A 1 256 ? 5.942   20.320  1.104   1.000 19.300 0 256 VAL A C   1 ? 
ATOM   1787 O O   . VAL A 1 256 ? 6.551   21.019  1.927   1.000 20.175 0 256 VAL A O   1 ? 
ATOM   1788 C CB  . VAL A 1 256 ? 5.089   21.827  -0.780  1.000 19.275 0 256 VAL A CB  1 ? 
ATOM   1789 C CG1 . VAL A 1 256 ? 5.189   22.106  -2.297  1.000 21.136 0 256 VAL A CG1 1 ? 
ATOM   1790 C CG2 . VAL A 1 256 ? 3.626   21.643  -0.376  1.000 18.400 0 256 VAL A CG2 1 ? 
ATOM   1791 N N   . ALA A 1 257 ? 5.288   19.205  1.427   1.000 19.364 0 257 ALA A N   1 ? 
ATOM   1792 C CA  . ALA A 1 257 ? 5.271   18.653  2.766   1.000 17.569 0 257 ALA A CA  1 ? 
ATOM   1793 C C   . ALA A 1 257 ? 4.852   17.195  2.650   1.000 18.002 0 257 ALA A C   1 ? 
ATOM   1794 O O   . ALA A 1 257 ? 4.417   16.795  1.569   1.000 17.696 0 257 ALA A O   1 ? 
ATOM   1795 C CB  . ALA A 1 257 ? 4.324   19.441  3.667   1.000 18.800 0 257 ALA A CB  1 ? 
ATOM   1796 N N   . PRO A 1 258 ? 5.023   16.375  3.696   1.000 17.343 0 258 PRO A N   1 ? 
ATOM   1797 C CA  . PRO A 1 258 ? 4.696   14.938  3.613   1.000 17.799 0 258 PRO A CA  1 ? 
ATOM   1798 C C   . PRO A 1 258 ? 3.220   14.780  3.280   1.000 19.224 0 258 PRO A C   1 ? 
ATOM   1799 O O   . PRO A 1 258 ? 2.395   15.402  3.937   1.000 19.121 0 258 PRO A O   1 ? 
ATOM   1800 C CB  . PRO A 1 258 ? 5.025   14.426  5.015   1.000 18.185 0 258 PRO A CB  1 ? 
ATOM   1801 C CG  . PRO A 1 258 ? 6.114   15.361  5.474   1.000 20.071 0 258 PRO A CG  1 ? 
ATOM   1802 C CD  . PRO A 1 258 ? 5.618   16.714  4.997   1.000 19.075 0 258 PRO A CD  1 ? 
ATOM   1803 N N   . ASN A 1 259 ? 2.933   14.049  2.203   1.000 19.166 0 259 ASN A N   1 ? 
ATOM   1804 C CA  . ASN A 1 259 ? 1.579   13.804  1.701   1.000 20.605 0 259 ASN A CA  1 ? 
ATOM   1805 C C   . ASN A 1 259 ? 0.850   15.118  1.405   1.000 18.791 0 259 ASN A C   1 ? 
ATOM   1806 O O   . ASN A 1 259 ? -0.362  15.220  1.572   1.000 19.278 0 259 ASN A O   1 ? 
ATOM   1807 C CB  . ASN A 1 259 ? 0.754   12.823  2.557   1.000 22.126 0 259 ASN A CB  1 ? 
ATOM   1808 C CG  . ASN A 1 259 ? -0.355  12.119  1.767   1.000 23.629 0 259 ASN A CG  1 ? 
ATOM   1809 O OD1 . ASN A 1 259 ? -0.449  12.206  0.541   1.000 28.135 0 259 ASN A OD1 1 ? 
ATOM   1810 N ND2 . ASN A 1 259 ? -1.252  11.440  2.453   1.000 28.675 0 259 ASN A ND2 1 ? 
ATOM   1811 N N   . ALA A 1 260 ? 1.551   16.089  0.824   1.000 19.515 0 260 ALA A N   1 ? 
ATOM   1812 C CA  . ALA A 1 260 ? 0.932   17.336  0.440   1.000 22.090 0 260 ALA A CA  1 ? 
ATOM   1813 C C   . ALA A 1 260 ? 0.996   17.468  -1.092  1.000 18.983 0 260 ALA A C   1 ? 
ATOM   1814 O O   . ALA A 1 260 ? 1.493   16.571  -1.757  1.000 19.019 0 260 ALA A O   1 ? 
ATOM   1815 C CB  . ALA A 1 260 ? 1.588   18.502  1.127   1.000 21.365 0 260 ALA A CB  1 ? 
ATOM   1816 N N   . GLY A 1 261 ? 0.606   18.637  -1.602  1.000 18.297 0 261 GLY A N   1 ? 
ATOM   1817 C CA  . GLY A 1 261 ? 0.723   18.897  -3.021  1.000 17.521 0 261 GLY A CA  1 ? 
ATOM   1818 C C   . GLY A 1 261 ? 2.168   19.122  -3.454  1.000 15.851 0 261 GLY A C   1 ? 
ATOM   1819 O O   . GLY A 1 261 ? 3.103   19.121  -2.666  1.000 17.398 0 261 GLY A O   1 ? 
ATOM   1820 N N   . TRP A 1 262 ? 2.316   19.336  -4.760  1.000 16.787 0 262 TRP A N   1 ? 
ATOM   1821 C CA  . TRP A 1 262 ? 3.593   19.275  -5.419  1.000 15.441 0 262 TRP A CA  1 ? 
ATOM   1822 C C   . TRP A 1 262 ? 4.015   20.663  -5.903  1.000 15.236 0 262 TRP A C   1 ? 
ATOM   1823 O O   . TRP A 1 262 ? 3.176   21.520  -6.201  1.000 16.115 0 262 TRP A O   1 ? 
ATOM   1824 C CB  . TRP A 1 262 ? 3.504   18.315  -6.615  1.000 14.765 0 262 TRP A CB  1 ? 
ATOM   1825 C CG  . TRP A 1 262 ? 3.282   16.892  -6.187  1.000 13.449 0 262 TRP A CG  1 ? 
ATOM   1826 C CD1 . TRP A 1 262 ? 2.098   16.356  -5.752  1.000 16.380 0 262 TRP A CD1 1 ? 
ATOM   1827 C CD2 . TRP A 1 262 ? 4.239   15.818  -6.125  1.000 13.332 0 262 TRP A CD2 1 ? 
ATOM   1828 N NE1 . TRP A 1 262 ? 2.242   15.019  -5.492  1.000 15.356 0 262 TRP A NE1 1 ? 
ATOM   1829 C CE2 . TRP A 1 262 ? 3.546   14.657  -5.707  1.000 14.411 0 262 TRP A CE2 1 ? 
ATOM   1830 C CE3 . TRP A 1 262 ? 5.612   15.703  -6.420  1.000 14.349 0 262 TRP A CE3 1 ? 
ATOM   1831 C CZ2 . TRP A 1 262 ? 4.200   13.443  -5.536  1.000 12.928 0 262 TRP A CZ2 1 ? 
ATOM   1832 C CZ3 . TRP A 1 262 ? 6.236   14.484  -6.298  1.000 12.786 0 262 TRP A CZ3 1 ? 
ATOM   1833 C CH2 . TRP A 1 262 ? 5.529   13.361  -5.862  1.000 13.697 0 262 TRP A CH2 1 ? 
ATOM   1834 N N   . THR A 1 263 ? 5.323   20.853  -6.081  1.000 14.020 0 263 THR A N   1 ? 
ATOM   1835 C CA  . THR A 1 263 ? 5.914   21.963  -6.789  1.000 13.668 0 263 THR A CA  1 ? 
ATOM   1836 C C   . THR A 1 263 ? 5.622   21.842  -8.271  1.000 13.192 0 263 THR A C   1 ? 
ATOM   1837 O O   . THR A 1 263 ? 5.016   20.893  -8.691  1.000 15.389 0 263 THR A O   1 ? 
ATOM   1838 C CB  . THR A 1 263 ? 7.433   21.959  -6.609  1.000 14.840 0 263 THR A CB  1 ? 
ATOM   1839 O OG1 . THR A 1 263 ? 7.984   20.788  -7.257  1.000 13.205 0 263 THR A OG1 1 ? 
ATOM   1840 C CG2 . THR A 1 263 ? 7.844   21.982  -5.156  1.000 15.050 0 263 THR A CG2 1 ? 
ATOM   1841 N N   . ASN A 1 264 ? 6.021   22.861  -9.014  1.000 15.685 0 264 ASN A N   1 ? 
ATOM   1842 C CA  . ASN A 1 264 ? 6.144   22.754  -10.451 1.000 15.003 0 264 ASN A CA  1 ? 
ATOM   1843 C C   . ASN A 1 264 ? 7.396   21.911  -10.783 1.000 14.531 0 264 ASN A C   1 ? 
ATOM   1844 O O   . ASN A 1 264 ? 8.270   21.645  -9.953  1.000 14.959 0 264 ASN A O   1 ? 
ATOM   1845 C CB  . ASN A 1 264 ? 6.158   24.148  -11.069 1.000 18.822 0 264 ASN A CB  1 ? 
ATOM   1846 C CG  . ASN A 1 264 ? 7.360   24.978  -10.680 1.000 22.848 0 264 ASN A CG  1 ? 
ATOM   1847 O OD1 . ASN A 1 264 ? 7.822   24.957  -9.538  1.000 25.072 0 264 ASN A OD1 1 ? 
ATOM   1848 N ND2 . ASN A 1 264 ? 7.898   25.727  -11.632 1.000 27.999 0 264 ASN A ND2 1 ? 
ATOM   1849 N N   . TRP A 1 265 ? 7.506   21.540  -12.060 1.000 13.646 0 265 TRP A N   1 ? 
ATOM   1850 C CA  . TRP A 1 265 ? 8.714   20.915  -12.562 1.000 12.796 0 265 TRP A CA  1 ? 
ATOM   1851 C C   . TRP A 1 265 ? 9.850   21.918  -12.613 1.000 13.126 0 265 TRP A C   1 ? 
ATOM   1852 O O   . TRP A 1 265 ? 9.658   23.066  -13.037 1.000 15.175 0 265 TRP A O   1 ? 
ATOM   1853 C CB  . TRP A 1 265 ? 8.505   20.369  -13.983 1.000 12.394 0 265 TRP A CB  1 ? 
ATOM   1854 C CG  . TRP A 1 265 ? 7.746   19.088  -14.048 1.000 12.924 0 265 TRP A CG  1 ? 
ATOM   1855 C CD1 . TRP A 1 265 ? 6.420   18.915  -14.326 1.000 13.238 0 265 TRP A CD1 1 ? 
ATOM   1856 C CD2 . TRP A 1 265 ? 8.298   17.789  -13.851 1.000 12.360 0 265 TRP A CD2 1 ? 
ATOM   1857 N NE1 . TRP A 1 265 ? 6.119   17.598  -14.300 1.000 13.124 0 265 TRP A NE1 1 ? 
ATOM   1858 C CE2 . TRP A 1 265 ? 7.248   16.879  -14.006 1.000 12.264 0 265 TRP A CE2 1 ? 
ATOM   1859 C CE3 . TRP A 1 265 ? 9.582   17.305  -13.545 1.000 12.139 0 265 TRP A CE3 1 ? 
ATOM   1860 C CZ2 . TRP A 1 265 ? 7.443   15.517  -13.882 1.000 13.011 0 265 TRP A CZ2 1 ? 
ATOM   1861 C CZ3 . TRP A 1 265 ? 9.778   15.964  -13.452 1.000 13.508 0 265 TRP A CZ3 1 ? 
ATOM   1862 C CH2 . TRP A 1 265 ? 8.717   15.073  -13.585 1.000 13.448 0 265 TRP A CH2 1 ? 
ATOM   1863 N N   . ARG A 1 266 ? 11.040  21.487  -12.166 1.000 12.341 0 266 ARG A N   1 ? 
ATOM   1864 C CA  . ARG A 1 266 ? 12.214  22.340  -12.109 1.000 13.854 0 266 ARG A CA  1 ? 
ATOM   1865 C C   . ARG A 1 266 ? 13.406  21.588  -12.683 1.000 13.105 0 266 ARG A C   1 ? 
ATOM   1866 O O   . ARG A 1 266 ? 13.515  20.361  -12.528 1.000 13.564 0 266 ARG A O   1 ? 
ATOM   1867 C CB  . ARG A 1 266 ? 12.471  22.795  -10.683 1.000 15.258 0 266 ARG A CB  1 ? 
ATOM   1868 C CG  . ARG A 1 266 ? 11.310  23.624  -10.157 1.000 17.401 0 266 ARG A CG  1 ? 
ATOM   1869 C CD  . ARG A 1 266 ? 11.688  24.441  -8.950  1.000 20.036 0 266 ARG A CD  1 ? 
ATOM   1870 N NE  . ARG A 1 266 ? 10.465  24.992  -8.369  1.000 21.853 0 266 ARG A NE  1 ? 
ATOM   1871 C CZ  . ARG A 1 266 ? 10.429  25.479  -7.140  1.000 22.318 0 266 ARG A CZ  1 ? 
ATOM   1872 N NH1 . ARG A 1 266 ? 11.559  25.735  -6.507  1.000 23.621 0 266 ARG A NH1 1 ? 
ATOM   1873 N NH2 . ARG A 1 266 ? 9.252   25.723  -6.588  1.000 22.786 0 266 ARG A NH2 1 ? 
ATOM   1874 N N   . SER A 1 267 ? 14.242  22.329  -13.400 1.000 13.233 0 267 SER A N   1 ? 
ATOM   1875 C CA  . SER A 1 267 ? 15.398  21.730  -14.062 1.000 13.547 0 267 SER A CA  1 ? 
ATOM   1876 C C   . SER A 1 267 ? 16.610  21.701  -13.139 1.000 14.388 0 267 SER A C   1 ? 
ATOM   1877 O O   . SER A 1 267 ? 16.958  22.708  -12.493 1.000 15.790 0 267 SER A O   1 ? 
ATOM   1878 C CB  . SER A 1 267 ? 15.722  22.451  -15.343 1.000 13.821 0 267 SER A CB  1 ? 
ATOM   1879 O OG  . SER A 1 267 ? 16.843  21.837  -16.003 1.000 13.969 0 267 SER A OG  1 ? 
ATOM   1880 N N   . LEU A 1 268 ? 17.328  20.568  -13.190 1.000 13.404 0 268 LEU A N   1 ? 
ATOM   1881 C CA  . LEU A 1 268 ? 18.660  20.430  -12.633 1.000 13.057 0 268 LEU A CA  1 ? 
ATOM   1882 C C   . LEU A 1 268 ? 19.711  20.384  -13.740 1.000 12.714 0 268 LEU A C   1 ? 
ATOM   1883 O O   . LEU A 1 268 ? 20.868  20.069  -13.448 1.000 13.412 0 268 LEU A O   1 ? 
ATOM   1884 C CB  . LEU A 1 268 ? 18.736  19.179  -11.759 1.000 12.595 0 268 LEU A CB  1 ? 
ATOM   1885 C CG  . LEU A 1 268 ? 17.983  19.280  -10.435 1.000 14.441 0 268 LEU A CG  1 ? 
ATOM   1886 C CD1 . LEU A 1 268 ? 17.913  17.928  -9.742  1.000 15.179 0 268 LEU A CD1 1 ? 
ATOM   1887 C CD2 . LEU A 1 268 ? 18.626  20.304  -9.498  1.000 17.335 0 268 LEU A CD2 1 ? 
ATOM   1888 N N   . SER A 1 269 ? 19.332  20.778  -14.961 1.000 12.595 0 269 SER A N   1 ? 
ATOM   1889 C CA  A SER A 1 269 ? 20.288  20.931  -16.047 0.700 14.112 0 269 SER A CA  1 ? 
ATOM   1890 C CA  B SER A 1 269 ? 20.238  20.916  -16.091 0.300 13.380 0 269 SER A CA  1 ? 
ATOM   1891 C C   . SER A 1 269 ? 20.972  19.597  -16.337 1.000 13.421 0 269 SER A C   1 ? 
ATOM   1892 O O   . SER A 1 269 ? 20.428  18.525  -16.056 1.000 12.675 0 269 SER A O   1 ? 
ATOM   1893 C CB  A SER A 1 269 ? 21.306  22.005  -15.751 0.700 15.377 0 269 SER A CB  1 ? 
ATOM   1894 C CB  B SER A 1 269 ? 21.158  22.102  -15.913 0.300 13.690 0 269 SER A CB  1 ? 
ATOM   1895 O OG  A SER A 1 269 ? 22.005  22.352  -16.933 0.700 17.871 0 269 SER A OG  1 ? 
ATOM   1896 O OG  B SER A 1 269 ? 20.403  23.304  -15.791 0.300 13.965 0 269 SER A OG  1 ? 
ATOM   1897 N N   . GLY A 1 270 ? 22.166  19.653  -16.939 1.000 13.755 0 270 GLY A N   1 ? 
ATOM   1898 C CA  . GLY A 1 270 ? 22.865  18.460  -17.364 1.000 13.580 0 270 GLY A CA  1 ? 
ATOM   1899 C C   . GLY A 1 270 ? 22.371  17.964  -18.719 1.000 13.345 0 270 GLY A C   1 ? 
ATOM   1900 O O   . GLY A 1 270 ? 21.383  18.477  -19.254 1.000 14.636 0 270 GLY A O   1 ? 
ATOM   1901 N N   . ILE A 1 271 ? 23.071  16.967  -19.290 1.000 13.773 0 271 ILE A N   1 ? 
ATOM   1902 C CA  . ILE A 1 271 ? 22.598  16.239  -20.464 1.000 14.108 0 271 ILE A CA  1 ? 
ATOM   1903 C C   . ILE A 1 271 ? 22.669  14.759  -20.108 1.000 12.771 0 271 ILE A C   1 ? 
ATOM   1904 O O   . ILE A 1 271 ? 23.741  14.237  -19.917 1.000 14.186 0 271 ILE A O   1 ? 
ATOM   1905 C CB  . ILE A 1 271 ? 23.401  16.532  -21.744 1.000 15.864 0 271 ILE A CB  1 ? 
ATOM   1906 C CG1 . ILE A 1 271 ? 23.184  17.965  -22.232 1.000 16.099 0 271 ILE A CG1 1 ? 
ATOM   1907 C CG2 . ILE A 1 271 ? 23.067  15.532  -22.836 1.000 15.290 0 271 ILE A CG2 1 ? 
ATOM   1908 C CD1 . ILE A 1 271 ? 21.793  18.230  -22.793 1.000 19.658 0 271 ILE A CD1 1 ? 
ATOM   1909 N N   . ILE A 1 272 ? 21.510  14.134  -19.879 1.000 13.224 0 272 ILE A N   1 ? 
ATOM   1910 C CA  . ILE A 1 272 ? 21.534  12.759  -19.411 1.000 13.236 0 272 ILE A CA  1 ? 
ATOM   1911 C C   . ILE A 1 272 ? 21.163  11.850  -20.582 1.000 13.236 0 272 ILE A C   1 ? 
ATOM   1912 O O   . ILE A 1 272 ? 20.221  12.131  -21.358 1.000 13.122 0 272 ILE A O   1 ? 
ATOM   1913 C CB  . ILE A 1 272 ? 20.731  12.491  -18.117 1.000 15.532 0 272 ILE A CB  1 ? 
ATOM   1914 C CG1 . ILE A 1 272 ? 19.243  12.771  -18.266 1.000 17.301 0 272 ILE A CG1 1 ? 
ATOM   1915 C CG2 . ILE A 1 272 ? 21.297  13.297  -16.949 1.000 16.280 0 272 ILE A CG2 1 ? 
ATOM   1916 C CD1 . ILE A 1 272 ? 18.429  12.296  -17.046 1.000 18.265 0 272 ILE A CD1 1 ? 
ATOM   1917 N N   . THR A 1 273 ? 21.945  10.757  -20.694 1.000 12.375 0 273 THR A N   1 ? 
ATOM   1918 C CA  . THR A 1 273 ? 21.799  9.833   -21.808 1.000 12.951 0 273 THR A CA  1 ? 
ATOM   1919 C C   . THR A 1 273 ? 21.380  8.452   -21.317 1.000 14.210 0 273 THR A C   1 ? 
ATOM   1920 O O   . THR A 1 273 ? 21.616  7.462   -21.997 1.000 14.990 0 273 THR A O   1 ? 
ATOM   1921 C CB  . THR A 1 273 ? 23.102  9.777   -22.619 1.000 13.835 0 273 THR A CB  1 ? 
ATOM   1922 O OG1 . THR A 1 273 ? 24.106  9.261   -21.735 1.000 12.610 0 273 THR A OG1 1 ? 
ATOM   1923 C CG2 . THR A 1 273 ? 23.499  11.131  -23.182 1.000 15.284 0 273 THR A CG2 1 ? 
ATOM   1924 N N   . SER A 1 274 ? 20.779  8.394   -20.129 1.000 12.627 0 274 SER A N   1 ? 
ATOM   1925 C CA  . SER A 1 274 ? 20.158  7.199   -19.588 1.000 11.884 0 274 SER A CA  1 ? 
ATOM   1926 C C   . SER A 1 274 ? 19.003  7.632   -18.701 1.000 12.043 0 274 SER A C   1 ? 
ATOM   1927 O O   . SER A 1 274 ? 18.955  8.789   -18.293 1.000 13.276 0 274 SER A O   1 ? 
ATOM   1928 C CB  . SER A 1 274 ? 21.128  6.382   -18.803 1.000 12.116 0 274 SER A CB  1 ? 
ATOM   1929 O OG  . SER A 1 274 ? 21.441  6.949   -17.532 1.000 12.229 0 274 SER A OG  1 ? 
ATOM   1930 N N   . ASP A 1 275 ? 18.182  6.658   -18.291 1.000 12.295 0 275 ASP A N   1 ? 
ATOM   1931 C CA  . ASP A 1 275 ? 17.352  6.879   -17.127 1.000 12.206 0 275 ASP A CA  1 ? 
ATOM   1932 C C   . ASP A 1 275 ? 18.197  7.343   -15.941 1.000 12.786 0 275 ASP A C   1 ? 
ATOM   1933 O O   . ASP A 1 275 ? 19.313  6.870   -15.735 1.000 12.438 0 275 ASP A O   1 ? 
ATOM   1934 C CB  . ASP A 1 275 ? 16.648  5.586   -16.728 1.000 12.765 0 275 ASP A CB  1 ? 
ATOM   1935 C CG  . ASP A 1 275 ? 15.541  5.100   -17.611 1.000 13.783 0 275 ASP A CG  1 ? 
ATOM   1936 O OD1 . ASP A 1 275 ? 14.994  5.886   -18.360 1.000 14.141 0 275 ASP A OD1 1 ? 
ATOM   1937 O OD2 . ASP A 1 275 ? 15.217  3.857   -17.507 1.000 17.061 0 275 ASP A OD2 1 ? 
ATOM   1938 N N   . PRO A 1 276 ? 17.638  8.228   -15.102 1.000 12.344 0 276 PRO A N   1 ? 
ATOM   1939 C CA  . PRO A 1 276 ? 18.259  8.570   -13.833 1.000 12.350 0 276 PRO A CA  1 ? 
ATOM   1940 C C   . PRO A 1 276 ? 17.984  7.497   -12.780 1.000 12.462 0 276 PRO A C   1 ? 
ATOM   1941 O O   . PRO A 1 276 ? 16.939  6.803   -12.816 1.000 12.751 0 276 PRO A O   1 ? 
ATOM   1942 C CB  . PRO A 1 276 ? 17.604  9.897   -13.490 1.000 13.347 0 276 PRO A CB  1 ? 
ATOM   1943 C CG  . PRO A 1 276 ? 16.246  9.814   -14.089 1.000 13.694 0 276 PRO A CG  1 ? 
ATOM   1944 C CD  . PRO A 1 276 ? 16.408  8.981   -15.343 1.000 13.392 0 276 PRO A CD  1 ? 
ATOM   1945 N N   . ALA A 1 277 ? 18.902  7.396   -11.821 1.000 11.955 0 277 ALA A N   1 ? 
ATOM   1946 C CA  . ALA A 1 277 ? 18.782  6.584   -10.627 1.000 12.013 0 277 ALA A CA  1 ? 
ATOM   1947 C C   . ALA A 1 277 ? 18.999  7.478   -9.428  1.000 13.903 0 277 ALA A C   1 ? 
ATOM   1948 O O   . ALA A 1 277 ? 19.663  8.499   -9.501  1.000 14.241 0 277 ALA A O   1 ? 
ATOM   1949 C CB  . ALA A 1 277 ? 19.788  5.445   -10.679 1.000 12.784 0 277 ALA A CB  1 ? 
ATOM   1950 N N   . VAL A 1 278 ? 18.370  7.135   -8.310  1.000 12.933 0 278 VAL A N   1 ? 
ATOM   1951 C CA  . VAL A 1 278 ? 18.474  7.989   -7.149  1.000 13.062 0 278 VAL A CA  1 ? 
ATOM   1952 C C   . VAL A 1 278 ? 18.468  7.143   -5.882  1.000 12.780 0 278 VAL A C   1 ? 
ATOM   1953 O O   . VAL A 1 278 ? 17.880  6.056   -5.829  1.000 13.179 0 278 VAL A O   1 ? 
ATOM   1954 C CB  . VAL A 1 278 ? 17.336  9.034   -7.138  1.000 13.522 0 278 VAL A CB  1 ? 
ATOM   1955 C CG1 . VAL A 1 278 ? 15.975  8.369   -7.043  1.000 13.333 0 278 VAL A CG1 1 ? 
ATOM   1956 C CG2 . VAL A 1 278 ? 17.514  10.042  -6.003  1.000 13.367 0 278 VAL A CG2 1 ? 
ATOM   1957 N N   . HIS A 1 279 ? 19.141  7.630   -4.832  1.000 12.262 0 279 HIS A N   1 ? 
ATOM   1958 C CA  . HIS A 1 279 ? 19.193  6.953   -3.540  1.000 12.348 0 279 HIS A CA  1 ? 
ATOM   1959 C C   . HIS A 1 279 ? 19.459  8.005   -2.481  1.000 14.056 0 279 HIS A C   1 ? 
ATOM   1960 O O   . HIS A 1 279 ? 20.097  9.014   -2.753  1.000 15.480 0 279 HIS A O   1 ? 
ATOM   1961 C CB  . HIS A 1 279 ? 20.318  5.885   -3.491  1.000 14.027 0 279 HIS A CB  1 ? 
ATOM   1962 C CG  . HIS A 1 279 ? 20.041  4.721   -2.637  1.000 17.579 0 279 HIS A CG  1 ? 
ATOM   1963 N ND1 . HIS A 1 279 ? 20.280  4.809   -1.272  1.000 23.066 0 279 HIS A ND1 1 ? 
ATOM   1964 C CD2 . HIS A 1 279 ? 19.531  3.483   -2.878  1.000 21.751 0 279 HIS A CD2 1 ? 
ATOM   1965 C CE1 . HIS A 1 279 ? 19.916  3.657   -0.712  1.000 25.429 0 279 HIS A CE1 1 ? 
ATOM   1966 N NE2 . HIS A 1 279 ? 19.460  2.862   -1.642  1.000 23.592 0 279 HIS A NE2 1 ? 
ATOM   1967 N N   . ILE A 1 280 ? 18.984  7.788   -1.253  1.000 15.580 0 280 ILE A N   1 ? 
ATOM   1968 C CA  . ILE A 1 280 ? 19.375  8.712   -0.196  1.000 16.473 0 280 ILE A CA  1 ? 
ATOM   1969 C C   . ILE A 1 280 ? 20.778  8.312   0.268   1.000 14.976 0 280 ILE A C   1 ? 
ATOM   1970 O O   . ILE A 1 280 ? 21.090  7.126   0.422   1.000 15.895 0 280 ILE A O   1 ? 
ATOM   1971 C CB  . ILE A 1 280 ? 18.319  8.705   0.921   1.000 22.669 0 280 ILE A CB  1 ? 
ATOM   1972 C CG1 . ILE A 1 280 ? 18.475  9.926   1.831   1.000 29.220 0 280 ILE A CG1 1 ? 
ATOM   1973 C CG2 . ILE A 1 280 ? 18.355  7.424   1.681   1.000 25.461 0 280 ILE A CG2 1 ? 
ATOM   1974 C CD1 . ILE A 1 280 ? 17.173  10.264  2.574   1.000 33.122 0 280 ILE A CD1 1 ? 
ATOM   1975 N N   . ASN A 1 281 ? 21.647  9.307   0.488   1.000 14.728 0 281 ASN A N   1 ? 
ATOM   1976 C CA  . ASN A 1 281 ? 23.025  9.041   0.912   1.000 16.496 0 281 ASN A CA  1 ? 
ATOM   1977 C C   . ASN A 1 281 ? 23.100  8.990   2.440   1.000 20.440 0 281 ASN A C   1 ? 
ATOM   1978 O O   . ASN A 1 281 ? 22.090  9.172   3.130   1.000 20.882 0 281 ASN A O   1 ? 
ATOM   1979 C CB  . ASN A 1 281 ? 23.989  10.015  0.223   1.000 17.704 0 281 ASN A CB  1 ? 
ATOM   1980 C CG  . ASN A 1 281 ? 23.802  11.473  0.602   1.000 18.296 0 281 ASN A CG  1 ? 
ATOM   1981 O OD1 . ASN A 1 281 ? 23.304  11.766  1.683   1.000 16.188 0 281 ASN A OD1 1 ? 
ATOM   1982 N ND2 . ASN A 1 281 ? 24.204  12.413  -0.260  1.000 20.538 0 281 ASN A ND2 1 ? 
ATOM   1983 N N   . ALA A 1 282 ? 24.337  8.917   2.957   1.000 25.622 0 282 ALA A N   1 ? 
ATOM   1984 C CA  . ALA A 1 282 ? 24.592  8.812   4.393   1.000 26.952 0 282 ALA A CA  1 ? 
ATOM   1985 C C   . ALA A 1 282 ? 24.282  10.112  5.136   1.000 28.029 0 282 ALA A C   1 ? 
ATOM   1986 O O   . ALA A 1 282 ? 24.084  10.103  6.352   1.000 29.729 0 282 ALA A O   1 ? 
ATOM   1987 C CB  . ALA A 1 282 ? 26.036  8.416   4.593   1.000 27.464 0 282 ALA A CB  1 ? 
ATOM   1988 N N   . ASP A 1 283 ? 24.208  11.234  4.414   1.000 21.991 0 283 ASP A N   1 ? 
ATOM   1989 C CA  . ASP A 1 283 ? 23.863  12.521  4.996   1.000 21.616 0 283 ASP A CA  1 ? 
ATOM   1990 C C   . ASP A 1 283 ? 22.355  12.754  4.999   1.000 19.975 0 283 ASP A C   1 ? 
ATOM   1991 O O   . ASP A 1 283 ? 21.929  13.859  5.351   1.000 21.855 0 283 ASP A O   1 ? 
ATOM   1992 C CB  . ASP A 1 283 ? 24.552  13.645  4.212   1.000 24.490 0 283 ASP A CB  1 ? 
ATOM   1993 C CG  . ASP A 1 283 ? 26.068  13.536  4.205   1.000 30.094 0 283 ASP A CG  1 ? 
ATOM   1994 O OD1 . ASP A 1 283 ? 26.600  13.246  5.273   1.000 30.643 0 283 ASP A OD1 1 ? 
ATOM   1995 O OD2 . ASP A 1 283 ? 26.690  13.661  3.131   1.000 32.134 0 283 ASP A OD2 1 ? 
ATOM   1996 N N   . GLY A 1 284 ? 21.545  11.755  4.566   1.000 18.709 0 284 GLY A N   1 ? 
ATOM   1997 C CA  . GLY A 1 284 ? 20.098  11.906  4.474   1.000 20.465 0 284 GLY A CA  1 ? 
ATOM   1998 C C   . GLY A 1 284 ? 19.655  12.790  3.309   1.000 18.365 0 284 GLY A C   1 ? 
ATOM   1999 O O   . GLY A 1 284 ? 18.533  13.317  3.269   1.000 23.603 0 284 GLY A O   1 ? 
ATOM   2000 N N   . ARG A 1 285 ? 20.517  12.952  2.294   1.000 16.569 0 285 ARG A N   1 ? 
ATOM   2001 C CA  . ARG A 1 285 ? 20.250  13.813  1.161   1.000 17.298 0 285 ARG A CA  1 ? 
ATOM   2002 C C   . ARG A 1 285 ? 20.093  12.907  -0.070  1.000 15.134 0 285 ARG A C   1 ? 
ATOM   2003 O O   . ARG A 1 285 ? 20.756  11.870  -0.198  1.000 16.146 0 285 ARG A O   1 ? 
ATOM   2004 C CB  . ARG A 1 285 ? 21.410  14.792  0.938   1.000 21.440 0 285 ARG A CB  1 ? 
ATOM   2005 C CG  . ARG A 1 285 ? 21.673  15.803  2.064   1.000 24.520 0 285 ARG A CG  1 ? 
ATOM   2006 C CD  . ARG A 1 285 ? 20.694  16.951  2.138   1.000 28.850 0 285 ARG A CD  1 ? 
ATOM   2007 N NE  . ARG A 1 285 ? 20.770  17.809  3.334   1.000 32.340 0 285 ARG A NE  1 ? 
ATOM   2008 C CZ  . ARG A 1 285 ? 21.784  18.570  3.739   1.000 44.383 0 285 ARG A CZ  1 ? 
ATOM   2009 N NH1 . ARG A 1 285 ? 22.981  18.538  3.177   1.000 44.161 0 285 ARG A NH1 1 ? 
ATOM   2010 N NH2 . ARG A 1 285 ? 21.590  19.369  4.770   1.000 48.517 0 285 ARG A NH2 1 ? 
ATOM   2011 N N   . LEU A 1 286 ? 19.204  13.305  -0.962  1.000 12.880 0 286 LEU A N   1 ? 
ATOM   2012 C CA  . LEU A 1 286 ? 19.041  12.608  -2.242  1.000 12.509 0 286 LEU A CA  1 ? 
ATOM   2013 C C   . LEU A 1 286 ? 20.265  12.841  -3.128  1.000 12.354 0 286 LEU A C   1 ? 
ATOM   2014 O O   . LEU A 1 286 ? 20.782  13.941  -3.264  1.000 13.020 0 286 LEU A O   1 ? 
ATOM   2015 C CB  . LEU A 1 286 ? 17.790  13.131  -2.954  1.000 12.063 0 286 LEU A CB  1 ? 
ATOM   2016 C CG  . LEU A 1 286 ? 16.470  12.963  -2.206  1.000 12.796 0 286 LEU A CG  1 ? 
ATOM   2017 C CD1 . LEU A 1 286 ? 15.289  13.334  -3.111  1.000 14.268 0 286 LEU A CD1 1 ? 
ATOM   2018 C CD2 . LEU A 1 286 ? 16.293  11.547  -1.715  1.000 13.676 0 286 LEU A CD2 1 ? 
ATOM   2019 N N   . GLU A 1 287 ? 20.667  11.764  -3.803  1.000 12.176 0 287 GLU A N   1 ? 
ATOM   2020 C CA  . GLU A 1 287 ? 21.802  11.785  -4.720  1.000 12.332 0 287 GLU A CA  1 ? 
ATOM   2021 C C   . GLU A 1 287 ? 21.377  11.040  -5.978  1.000 12.005 0 287 GLU A C   1 ? 
ATOM   2022 O O   . GLU A 1 287 ? 20.969  9.856   -5.897  1.000 12.144 0 287 GLU A O   1 ? 
ATOM   2023 C CB  . GLU A 1 287 ? 23.034  11.212  -4.040  1.000 13.932 0 287 GLU A CB  1 ? 
ATOM   2024 C CG  . GLU A 1 287 ? 24.305  11.339  -4.847  1.000 16.481 0 287 GLU A CG  1 ? 
ATOM   2025 C CD  . GLU A 1 287 ? 25.568  11.175  -4.020  1.000 17.679 0 287 GLU A CD  1 ? 
ATOM   2026 O OE1 . GLU A 1 287 ? 26.641  10.910  -4.573  1.000 16.706 0 287 GLU A OE1 1 ? 
ATOM   2027 O OE2 . GLU A 1 287 ? 25.482  11.327  -2.748  1.000 19.325 0 287 GLU A OE2 1 ? 
ATOM   2028 N N   . VAL A 1 288 ? 21.463  11.727  -7.137  1.000 11.031 0 288 VAL A N   1 ? 
ATOM   2029 C CA  . VAL A 1 288 ? 21.011  11.221  -8.402  1.000 10.822 0 288 VAL A CA  1 ? 
ATOM   2030 C C   . VAL A 1 288 ? 22.223  10.884  -9.260  1.000 11.747 0 288 VAL A C   1 ? 
ATOM   2031 O O   . VAL A 1 288 ? 23.250  11.617  -9.258  1.000 12.264 0 288 VAL A O   1 ? 
ATOM   2032 C CB  . VAL A 1 288 ? 20.128  12.251  -9.106  1.000 11.690 0 288 VAL A CB  1 ? 
ATOM   2033 C CG1 . VAL A 1 288 ? 19.696  11.768  -10.488 1.000 13.966 0 288 VAL A CG1 1 ? 
ATOM   2034 C CG2 . VAL A 1 288 ? 18.913  12.638  -8.285  1.000 14.189 0 288 VAL A CG2 1 ? 
ATOM   2035 N N   . PHE A 1 289 ? 22.128  9.740   -9.944  1.000 10.975 0 289 PHE A N   1 ? 
ATOM   2036 C CA  . PHE A 1 289 ? 23.136  9.245   -10.859 1.000 10.103 0 289 PHE A CA  1 ? 
ATOM   2037 C C   . PHE A 1 289 ? 22.563  9.051   -12.250 1.000 10.160 0 289 PHE A C   1 ? 
ATOM   2038 O O   . PHE A 1 289 ? 21.440  8.563   -12.410 1.000 11.606 0 289 PHE A O   1 ? 
ATOM   2039 C CB  . PHE A 1 289 ? 23.695  7.918   -10.346 1.000 10.161 0 289 PHE A CB  1 ? 
ATOM   2040 C CG  . PHE A 1 289 ? 24.325  7.984   -8.979  1.000 10.342 0 289 PHE A CG  1 ? 
ATOM   2041 C CD1 . PHE A 1 289 ? 23.579  7.990   -7.825  1.000 10.657 0 289 PHE A CD1 1 ? 
ATOM   2042 C CD2 . PHE A 1 289 ? 25.702  8.057   -8.877  1.000 10.192 0 289 PHE A CD2 1 ? 
ATOM   2043 C CE1 . PHE A 1 289 ? 24.191  8.083   -6.592  1.000 11.961 0 289 PHE A CE1 1 ? 
ATOM   2044 C CE2 . PHE A 1 289 ? 26.299  8.153   -7.627  1.000 10.380 0 289 PHE A CE2 1 ? 
ATOM   2045 C CZ  . PHE A 1 289 ? 25.529  8.169   -6.501  1.000 12.040 0 289 PHE A CZ  1 ? 
ATOM   2046 N N   . ALA A 1 290 ? 23.374  9.338   -13.261 1.000 10.449 0 290 ALA A N   1 ? 
ATOM   2047 C CA  . ALA A 1 290 ? 22.915  9.140   -14.625 1.000 10.913 0 290 ALA A CA  1 ? 
ATOM   2048 C C   . ALA A 1 290 ? 24.114  9.066   -15.544 1.000 10.235 0 290 ALA A C   1 ? 
ATOM   2049 O O   . ALA A 1 290 ? 25.181  9.630   -15.245 1.000 12.414 0 290 ALA A O   1 ? 
ATOM   2050 C CB  . ALA A 1 290 ? 22.000  10.252  -15.063 1.000 12.500 0 290 ALA A CB  1 ? 
ATOM   2051 N N   . ARG A 1 291 ? 23.941  8.455   -16.721 1.000 11.405 0 291 ARG A N   1 ? 
ATOM   2052 C CA  . ARG A 1 291 ? 24.943  8.556   -17.749 1.000 11.104 0 291 ARG A CA  1 ? 
ATOM   2053 C C   . ARG A 1 291 ? 24.922  9.943   -18.387 1.000 11.974 0 291 ARG A C   1 ? 
ATOM   2054 O O   . ARG A 1 291 ? 23.866  10.522  -18.602 1.000 12.128 0 291 ARG A O   1 ? 
ATOM   2055 C CB  . ARG A 1 291 ? 24.748  7.476   -18.806 1.000 12.027 0 291 ARG A CB  1 ? 
ATOM   2056 C CG  . ARG A 1 291 ? 25.964  7.267   -19.686 1.000 14.041 0 291 ARG A CG  1 ? 
ATOM   2057 C CD  . ARG A 1 291 ? 25.818  6.160   -20.703 1.000 16.016 0 291 ARG A CD  1 ? 
ATOM   2058 N NE  . ARG A 1 291 ? 24.866  6.477   -21.707 1.000 18.244 0 291 ARG A NE  1 ? 
ATOM   2059 C CZ  . ARG A 1 291 ? 24.718  5.758   -22.803 1.000 19.739 0 291 ARG A CZ  1 ? 
ATOM   2060 N NH1 . ARG A 1 291 ? 25.482  4.699   -23.005 1.000 19.454 0 291 ARG A NH1 1 ? 
ATOM   2061 N NH2 . ARG A 1 291 ? 23.797  6.122   -23.667 1.000 18.704 0 291 ARG A NH2 1 ? 
ATOM   2062 N N   . GLY A 1 292 ? 26.108  10.454  -18.738 1.000 12.490 0 292 GLY A N   1 ? 
ATOM   2063 C CA  . GLY A 1 292 ? 26.249  11.748  -19.361 1.000 12.070 0 292 GLY A CA  1 ? 
ATOM   2064 C C   . GLY A 1 292 ? 26.556  11.646  -20.840 1.000 14.890 0 292 GLY A C   1 ? 
ATOM   2065 O O   . GLY A 1 292 ? 26.648  10.554  -21.419 1.000 15.620 0 292 GLY A O   1 ? 
ATOM   2066 N N   . PRO A 1 293 ? 26.822  12.791  -21.476 1.000 14.942 0 293 PRO A N   1 ? 
ATOM   2067 C CA  . PRO A 1 293 ? 27.006  12.766  -22.916 1.000 16.540 0 293 PRO A CA  1 ? 
ATOM   2068 C C   . PRO A 1 293 ? 28.387  12.301  -23.359 1.000 19.006 0 293 PRO A C   1 ? 
ATOM   2069 O O   . PRO A 1 293 ? 28.563  12.010  -24.540 1.000 23.810 0 293 PRO A O   1 ? 
ATOM   2070 C CB  . PRO A 1 293 ? 26.712  14.223  -23.241 1.000 17.210 0 293 PRO A CB  1 ? 
ATOM   2071 C CG  . PRO A 1 293 ? 27.190  14.996  -22.092 1.000 16.092 0 293 PRO A CG  1 ? 
ATOM   2072 C CD  . PRO A 1 293 ? 26.923  14.128  -20.879 1.000 15.794 0 293 PRO A CD  1 ? 
ATOM   2073 N N   . ASP A 1 294 ? 29.321  12.156  -22.414 1.000 13.477 0 294 ASP A N   1 ? 
ATOM   2074 C CA  . ASP A 1 294 ? 30.636  11.560  -22.619 1.000 13.770 0 294 ASP A CA  1 ? 
ATOM   2075 C C   . ASP A 1 294 ? 30.670  10.082  -22.216 1.000 13.843 0 294 ASP A C   1 ? 
ATOM   2076 O O   . ASP A 1 294 ? 31.744  9.498   -22.087 1.000 16.005 0 294 ASP A O   1 ? 
ATOM   2077 C CB  . ASP A 1 294 ? 31.674  12.355  -21.828 1.000 13.192 0 294 ASP A CB  1 ? 
ATOM   2078 C CG  . ASP A 1 294 ? 31.401  12.471  -20.328 1.000 13.796 0 294 ASP A CG  1 ? 
ATOM   2079 O OD1 . ASP A 1 294 ? 30.312  11.997  -19.912 1.000 13.239 0 294 ASP A OD1 1 ? 
ATOM   2080 O OD2 . ASP A 1 294 ? 32.213  13.109  -19.606 1.000 14.181 0 294 ASP A OD2 1 ? 
ATOM   2081 N N   . ASN A 1 295 ? 29.477  9.513   -21.951 1.000 15.767 0 295 ASN A N   1 ? 
ATOM   2082 C CA  . ASN A 1 295 ? 29.267  8.136   -21.519 1.000 16.623 0 295 ASN A CA  1 ? 
ATOM   2083 C C   . ASN A 1 295 ? 29.884  7.838   -20.167 1.000 15.574 0 295 ASN A C   1 ? 
ATOM   2084 O O   . ASN A 1 295 ? 30.009  6.665   -19.809 1.000 13.997 0 295 ASN A O   1 ? 
ATOM   2085 C CB  . ASN A 1 295 ? 29.670  7.120   -22.582 1.000 18.750 0 295 ASN A CB  1 ? 
ATOM   2086 C CG  . ASN A 1 295 ? 28.769  7.251   -23.784 1.000 22.421 0 295 ASN A CG  1 ? 
ATOM   2087 O OD1 . ASN A 1 295 ? 27.559  7.423   -23.654 1.000 22.949 0 295 ASN A OD1 1 ? 
ATOM   2088 N ND2 . ASN A 1 295 ? 29.378  7.278   -24.949 1.000 30.575 0 295 ASN A ND2 1 ? 
ATOM   2089 N N   . ALA A 1 296 ? 30.236  8.892   -19.431 1.000 13.362 0 296 ALA A N   1 ? 
ATOM   2090 C CA  . ALA A 1 296 ? 30.673  8.739   -18.055 1.000 11.384 0 296 ALA A CA  1 ? 
ATOM   2091 C C   . ALA A 1 296 ? 29.470  8.657   -17.125 1.000 11.227 0 296 ALA A C   1 ? 
ATOM   2092 O O   . ALA A 1 296 ? 28.379  9.035   -17.476 1.000 12.745 0 296 ALA A O   1 ? 
ATOM   2093 C CB  . ALA A 1 296 ? 31.583  9.857   -17.619 1.000 12.167 0 296 ALA A CB  1 ? 
ATOM   2094 N N   . LEU A 1 297 ? 29.726  8.214   -15.881 1.000 11.637 0 297 LEU A N   1 ? 
ATOM   2095 C CA  . LEU A 1 297 ? 28.745  8.308   -14.820 1.000 11.924 0 297 LEU A CA  1 ? 
ATOM   2096 C C   . LEU A 1 297 ? 28.824  9.687   -14.176 1.000 11.853 0 297 LEU A C   1 ? 
ATOM   2097 O O   . LEU A 1 297 ? 29.910  10.066  -13.791 1.000 12.653 0 297 LEU A O   1 ? 
ATOM   2098 C CB  . LEU A 1 297 ? 29.047  7.242   -13.768 1.000 11.658 0 297 LEU A CB  1 ? 
ATOM   2099 C CG  . LEU A 1 297 ? 28.138  7.282   -12.533 1.000 11.944 0 297 LEU A CG  1 ? 
ATOM   2100 C CD1 . LEU A 1 297 ? 26.694  6.947   -12.907 1.000 12.241 0 297 LEU A CD1 1 ? 
ATOM   2101 C CD2 . LEU A 1 297 ? 28.630  6.357   -11.403 1.000 13.750 0 297 LEU A CD2 1 ? 
ATOM   2102 N N   . TRP A 1 298 ? 27.698  10.413  -14.076 1.000 10.951 0 298 TRP A N   1 ? 
ATOM   2103 C CA  . TRP A 1 298 ? 27.652  11.679  -13.394 1.000 10.844 0 298 TRP A CA  1 ? 
ATOM   2104 C C   . TRP A 1 298 ? 26.713  11.586  -12.207 1.000 10.973 0 298 TRP A C   1 ? 
ATOM   2105 O O   . TRP A 1 298 ? 25.801  10.767  -12.190 1.000 11.349 0 298 TRP A O   1 ? 
ATOM   2106 C CB  . TRP A 1 298 ? 27.191  12.764  -14.382 1.000 11.251 0 298 TRP A CB  1 ? 
ATOM   2107 C CG  . TRP A 1 298 ? 28.191  13.048  -15.479 1.000 11.005 0 298 TRP A CG  1 ? 
ATOM   2108 C CD1 . TRP A 1 298 ? 28.524  12.290  -16.565 1.000 11.446 0 298 TRP A CD1 1 ? 
ATOM   2109 C CD2 . TRP A 1 298 ? 29.025  14.227  -15.554 1.000 11.658 0 298 TRP A CD2 1 ? 
ATOM   2110 N NE1 . TRP A 1 298 ? 29.469  12.919  -17.318 1.000 11.748 0 298 TRP A NE1 1 ? 
ATOM   2111 C CE2 . TRP A 1 298 ? 29.773  14.126  -16.757 1.000 11.814 0 298 TRP A CE2 1 ? 
ATOM   2112 C CE3 . TRP A 1 298 ? 29.148  15.390  -14.775 1.000 11.554 0 298 TRP A CE3 1 ? 
ATOM   2113 C CZ2 . TRP A 1 298 ? 30.664  15.119  -17.158 1.000 11.113 0 298 TRP A CZ2 1 ? 
ATOM   2114 C CZ3 . TRP A 1 298 ? 30.012  16.381  -15.188 1.000 12.182 0 298 TRP A CZ3 1 ? 
ATOM   2115 C CH2 . TRP A 1 298 ? 30.751  16.237  -16.363 1.000 12.066 0 298 TRP A CH2 1 ? 
ATOM   2116 N N   . HIS A 1 299 ? 26.886  12.459  -11.209 1.000 11.858 0 299 HIS A N   1 ? 
ATOM   2117 C CA  . HIS A 1 299 ? 25.981  12.521  -10.087 1.000 11.530 0 299 HIS A CA  1 ? 
ATOM   2118 C C   . HIS A 1 299 ? 25.846  13.962  -9.603  1.000 10.711 0 299 HIS A C   1 ? 
ATOM   2119 O O   . HIS A 1 299 ? 26.680  14.807  -9.928  1.000 12.283 0 299 HIS A O   1 ? 
ATOM   2120 C CB  . HIS A 1 299 ? 26.400  11.560  -8.963  1.000 12.304 0 299 HIS A CB  1 ? 
ATOM   2121 C CG  . HIS A 1 299 ? 27.673  11.800  -8.249  1.000 12.260 0 299 HIS A CG  1 ? 
ATOM   2122 N ND1 . HIS A 1 299 ? 27.808  11.590  -6.881  1.000 13.435 0 299 HIS A ND1 1 ? 
ATOM   2123 C CD2 . HIS A 1 299 ? 28.898  12.206  -8.695  1.000 12.929 0 299 HIS A CD2 1 ? 
ATOM   2124 C CE1 . HIS A 1 299 ? 29.065  11.865  -6.545  1.000 12.934 0 299 HIS A CE1 1 ? 
ATOM   2125 N NE2 . HIS A 1 299 ? 29.767  12.218  -7.615  1.000 13.949 0 299 HIS A NE2 1 ? 
ATOM   2126 N N   . ILE A 1 300 ? 24.801  14.182  -8.811  1.000 10.551 0 300 ILE A N   1 ? 
ATOM   2127 C CA  . ILE A 1 300 ? 24.362  15.477  -8.327  1.000 11.248 0 300 ILE A CA  1 ? 
ATOM   2128 C C   . ILE A 1 300 ? 23.582  15.196  -7.064  1.000 11.323 0 300 ILE A C   1 ? 
ATOM   2129 O O   . ILE A 1 300 ? 22.939  14.156  -6.965  1.000 12.597 0 300 ILE A O   1 ? 
ATOM   2130 C CB  . ILE A 1 300 ? 23.573  16.233  -9.405  1.000 11.290 0 300 ILE A CB  1 ? 
ATOM   2131 C CG1 . ILE A 1 300 ? 23.442  17.716  -9.083  1.000 13.721 0 300 ILE A CG1 1 ? 
ATOM   2132 C CG2 . ILE A 1 300 ? 22.230  15.586  -9.735  1.000 12.310 0 300 ILE A CG2 1 ? 
ATOM   2133 C CD1 . ILE A 1 300 ? 22.764  18.552  -10.132 1.000 12.677 0 300 ILE A CD1 1 ? 
ATOM   2134 N N   . TRP A 1 301 ? 23.651  16.074  -6.066  1.000 11.815 0 301 TRP A N   1 ? 
ATOM   2135 C CA  . TRP A 1 301 ? 23.018  15.814  -4.779  1.000 11.694 0 301 TRP A CA  1 ? 
ATOM   2136 C C   . TRP A 1 301 ? 22.484  17.086  -4.133  1.000 12.250 0 301 TRP A C   1 ? 
ATOM   2137 O O   . TRP A 1 301 ? 22.942  18.200  -4.415  1.000 13.203 0 301 TRP A O   1 ? 
ATOM   2138 C CB  . TRP A 1 301 ? 23.984  15.114  -3.841  1.000 13.169 0 301 TRP A CB  1 ? 
ATOM   2139 C CG  . TRP A 1 301 ? 25.283  15.842  -3.659  1.000 12.276 0 301 TRP A CG  1 ? 
ATOM   2140 C CD1 . TRP A 1 301 ? 25.551  16.847  -2.770  1.000 13.336 0 301 TRP A CD1 1 ? 
ATOM   2141 C CD2 . TRP A 1 301 ? 26.455  15.739  -4.501  1.000 13.086 0 301 TRP A CD2 1 ? 
ATOM   2142 N NE1 . TRP A 1 301 ? 26.828  17.336  -2.966  1.000 12.989 0 301 TRP A NE1 1 ? 
ATOM   2143 C CE2 . TRP A 1 301 ? 27.422  16.677  -4.004  1.000 12.324 0 301 TRP A CE2 1 ? 
ATOM   2144 C CE3 . TRP A 1 301 ? 26.802  14.939  -5.588  1.000 12.612 0 301 TRP A CE3 1 ? 
ATOM   2145 C CZ2 . TRP A 1 301 ? 28.670  16.845  -4.602  1.000 13.042 0 301 TRP A CZ2 1 ? 
ATOM   2146 C CZ3 . TRP A 1 301 ? 28.026  15.138  -6.192  1.000 11.864 0 301 TRP A CZ3 1 ? 
ATOM   2147 C CH2 . TRP A 1 301 ? 28.938  16.100  -5.731  1.000 12.194 0 301 TRP A CH2 1 ? 
ATOM   2148 N N   . GLN A 1 302 ? 21.522  16.877  -3.226  1.000 12.298 0 302 GLN A N   1 ? 
ATOM   2149 C CA  . GLN A 1 302 ? 21.014  17.939  -2.381  1.000 13.199 0 302 GLN A CA  1 ? 
ATOM   2150 C C   . GLN A 1 302 ? 22.099  18.412  -1.409  1.000 13.504 0 302 GLN A C   1 ? 
ATOM   2151 O O   . GLN A 1 302 ? 22.872  17.616  -0.907  1.000 14.166 0 302 GLN A O   1 ? 
ATOM   2152 C CB  . GLN A 1 302 ? 19.849  17.428  -1.568  1.000 13.390 0 302 GLN A CB  1 ? 
ATOM   2153 C CG  . GLN A 1 302 ? 18.622  17.082  -2.387  1.000 12.901 0 302 GLN A CG  1 ? 
ATOM   2154 C CD  . GLN A 1 302 ? 17.565  16.459  -1.513  1.000 13.285 0 302 GLN A CD  1 ? 
ATOM   2155 O OE1 . GLN A 1 302 ? 17.837  15.780  -0.513  1.000 12.803 0 302 GLN A OE1 1 ? 
ATOM   2156 N NE2 . GLN A 1 302 ? 16.318  16.658  -1.899  1.000 13.352 0 302 GLN A NE2 1 ? 
ATOM   2157 N N   . THR A 1 303 ? 22.133  19.756  -1.276  1.000 14.555 0 303 THR A N   1 ? 
ATOM   2158 C CA  . THR A 1 303 ? 23.132  20.385  -0.434  1.000 17.678 0 303 THR A CA  1 ? 
ATOM   2159 C C   . THR A 1 303 ? 22.481  21.125  0.729   1.000 19.306 0 303 THR A C   1 ? 
ATOM   2160 O O   . THR A 1 303 ? 23.217  21.700  1.540   1.000 19.935 0 303 THR A O   1 ? 
ATOM   2161 C CB  . THR A 1 303 ? 24.007  21.346  -1.248  1.000 16.004 0 303 THR A CB  1 ? 
ATOM   2162 O OG1 . THR A 1 303 ? 23.200  22.351  -1.870  1.000 19.789 0 303 THR A OG1 1 ? 
ATOM   2163 C CG2 . THR A 1 303 ? 24.799  20.649  -2.334  1.000 15.877 0 303 THR A CG2 1 ? 
ATOM   2164 N N   . ALA A 1 304 ? 21.139  21.144  0.781   1.000 20.419 0 304 ALA A N   1 ? 
ATOM   2165 C CA  . ALA A 1 304 ? 20.395  21.732  1.887   1.000 22.133 0 304 ALA A CA  1 ? 
ATOM   2166 C C   . ALA A 1 304 ? 18.984  21.145  1.840   1.000 23.543 0 304 ALA A C   1 ? 
ATOM   2167 O O   . ALA A 1 304 ? 18.682  20.394  0.914   1.000 25.146 0 304 ALA A O   1 ? 
ATOM   2168 C CB  . ALA A 1 304 ? 20.406  23.231  1.745   1.000 23.304 0 304 ALA A CB  1 ? 
ATOM   2169 N N   . THR A 1 305 ? 18.125  21.459  2.814   1.000 25.659 0 305 THR A N   1 ? 
ATOM   2170 C CA  . THR A 1 305 ? 16.746  20.976  2.781   1.000 28.965 0 305 THR A CA  1 ? 
ATOM   2171 C C   . THR A 1 305 ? 15.927  21.801  1.792   1.000 26.897 0 305 THR A C   1 ? 
ATOM   2172 O O   . THR A 1 305 ? 15.031  21.289  1.123   1.000 28.176 0 305 THR A O   1 ? 
ATOM   2173 C CB  . THR A 1 305 ? 16.098  21.040  4.169   1.000 32.382 0 305 THR A CB  1 ? 
ATOM   2174 O OG1 . THR A 1 305 ? 16.895  20.216  5.014   1.000 32.500 0 305 THR A OG1 1 ? 
ATOM   2175 C CG2 . THR A 1 305 ? 14.645  20.595  4.182   1.000 33.126 0 305 THR A CG2 1 ? 
ATOM   2176 N N   . SER A 1 306 ? 16.217  23.098  1.735   1.000 25.853 0 306 SER A N   1 ? 
ATOM   2177 C CA  . SER A 1 306 ? 15.693  23.913  0.666   1.000 28.532 0 306 SER A CA  1 ? 
ATOM   2178 C C   . SER A 1 306 ? 16.226  23.276  -0.597  1.000 32.215 0 306 SER A C   1 ? 
ATOM   2179 O O   . SER A 1 306 ? 17.125  22.420  -0.538  1.000 33.937 0 306 SER A O   1 ? 
ATOM   2180 C CB  . SER A 1 306 ? 16.084  25.384  0.817   1.000 35.043 0 306 SER A CB  1 ? 
ATOM   2181 O OG  . SER A 1 306 ? 17.487  25.574  0.659   1.000 32.316 0 306 SER A OG  1 ? 
ATOM   2182 N N   . ASP A 1 307 ? 15.663  23.705  -1.709  1.000 27.286 0 307 ASP A N   1 ? 
ATOM   2183 C CA  . ASP A 1 307 ? 15.979  23.145  -3.008  1.000 25.929 0 307 ASP A CA  1 ? 
ATOM   2184 C C   . ASP A 1 307 ? 17.342  23.654  -3.441  1.000 25.041 0 307 ASP A C   1 ? 
ATOM   2185 O O   . ASP A 1 307 ? 17.437  24.476  -4.351  1.000 29.477 0 307 ASP A O   1 ? 
ATOM   2186 C CB  . ASP A 1 307 ? 14.919  23.535  -4.032  1.000 23.654 0 307 ASP A CB  1 ? 
ATOM   2187 C CG  . ASP A 1 307 ? 15.192  22.973  -5.414  1.000 25.462 0 307 ASP A CG  1 ? 
ATOM   2188 O OD1 . ASP A 1 307 ? 15.626  21.805  -5.477  1.000 22.008 0 307 ASP A OD1 1 ? 
ATOM   2189 O OD2 . ASP A 1 307 ? 14.912  23.702  -6.409  1.000 25.594 0 307 ASP A OD2 1 ? 
ATOM   2190 N N   . ALA A 1 308 ? 18.380  23.206  -2.743  1.000 20.455 0 308 ALA A N   1 ? 
ATOM   2191 C CA  . ALA A 1 308 ? 19.740  23.531  -3.105  1.000 18.646 0 308 ALA A CA  1 ? 
ATOM   2192 C C   . ALA A 1 308 ? 20.388  22.223  -3.537  1.000 16.855 0 308 ALA A C   1 ? 
ATOM   2193 O O   . ALA A 1 308 ? 20.257  21.222  -2.827  1.000 17.575 0 308 ALA A O   1 ? 
ATOM   2194 C CB  . ALA A 1 308 ? 20.473  24.136  -1.947  1.000 18.969 0 308 ALA A CB  1 ? 
ATOM   2195 N N   . TRP A 1 309 ? 21.051  22.264  -4.691  1.000 15.859 0 309 TRP A N   1 ? 
ATOM   2196 C CA  . TRP A 1 309 ? 21.742  21.107  -5.230  1.000 15.583 0 309 TRP A CA  1 ? 
ATOM   2197 C C   . TRP A 1 309 ? 23.161  21.480  -5.662  1.000 14.447 0 309 TRP A C   1 ? 
ATOM   2198 O O   . TRP A 1 309 ? 23.480  22.641  -5.934  1.000 16.125 0 309 TRP A O   1 ? 
ATOM   2199 C CB  . TRP A 1 309 ? 20.977  20.550  -6.439  1.000 15.009 0 309 TRP A CB  1 ? 
ATOM   2200 C CG  . TRP A 1 309 ? 19.685  19.855  -6.110  1.000 15.603 0 309 TRP A CG  1 ? 
ATOM   2201 C CD1 . TRP A 1 309 ? 18.485  20.395  -5.712  1.000 16.452 0 309 TRP A CD1 1 ? 
ATOM   2202 C CD2 . TRP A 1 309 ? 19.468  18.436  -6.139  1.000 12.486 0 309 TRP A CD2 1 ? 
ATOM   2203 N NE1 . TRP A 1 309 ? 17.557  19.404  -5.465  1.000 15.247 0 309 TRP A NE1 1 ? 
ATOM   2204 C CE2 . TRP A 1 309 ? 18.141  18.185  -5.717  1.000 13.399 0 309 TRP A CE2 1 ? 
ATOM   2205 C CE3 . TRP A 1 309 ? 20.269  17.339  -6.500  1.000 12.696 0 309 TRP A CE3 1 ? 
ATOM   2206 C CZ2 . TRP A 1 309 ? 17.634  16.894  -5.701  1.000 12.776 0 309 TRP A CZ2 1 ? 
ATOM   2207 C CZ3 . TRP A 1 309 ? 19.758  16.075  -6.445  1.000 13.825 0 309 TRP A CZ3 1 ? 
ATOM   2208 C CH2 . TRP A 1 309 ? 18.464  15.846  -6.019  1.000 13.534 0 309 TRP A CH2 1 ? 
ATOM   2209 N N   . SER A 1 310 ? 23.998  20.463  -5.706  1.000 12.128 0 310 SER A N   1 ? 
ATOM   2210 C CA  . SER A 1 310 ? 25.395  20.553  -6.043  1.000 12.203 0 310 SER A CA  1 ? 
ATOM   2211 C C   . SER A 1 310 ? 25.510  20.795  -7.538  1.000 13.026 0 310 SER A C   1 ? 
ATOM   2212 O O   . SER A 1 310 ? 24.514  20.763  -8.236  1.000 14.681 0 310 SER A O   1 ? 
ATOM   2213 C CB  . SER A 1 310 ? 26.094  19.321  -5.645  1.000 14.012 0 310 SER A CB  1 ? 
ATOM   2214 O OG  . SER A 1 310 ? 25.792  18.249  -6.570  1.000 12.951 0 310 SER A OG  1 ? 
ATOM   2215 N N   . GLU A 1 311 ? 26.747  20.989  -7.988  1.000 15.658 0 311 GLU A N   1 ? 
ATOM   2216 C CA  . GLU A 1 311 ? 27.027  20.907  -9.409  1.000 17.360 0 311 GLU A CA  1 ? 
ATOM   2217 C C   . GLU A 1 311 ? 26.976  19.439  -9.834  1.000 15.376 0 311 GLU A C   1 ? 
ATOM   2218 O O   . GLU A 1 311 ? 27.284  18.531  -9.056  1.000 14.038 0 311 GLU A O   1 ? 
ATOM   2219 C CB  . GLU A 1 311 ? 28.444  21.413  -9.729  1.000 22.964 0 311 GLU A CB  1 ? 
ATOM   2220 C CG  . GLU A 1 311 ? 28.688  22.881  -9.414  1.000 30.722 0 311 GLU A CG  1 ? 
ATOM   2221 C CD  . GLU A 1 311 ? 27.962  23.819  -10.350 1.000 35.012 0 311 GLU A CD  1 ? 
ATOM   2222 O OE1 . GLU A 1 311 ? 28.329  23.874  -11.533 1.000 41.109 0 311 GLU A OE1 1 ? 
ATOM   2223 O OE2 . GLU A 1 311 ? 27.007  24.465  -9.892  1.000 45.759 0 311 GLU A OE2 1 ? 
ATOM   2224 N N   . TRP A 1 312 ? 26.640  19.228  -11.112 1.000 13.789 0 312 TRP A N   1 ? 
ATOM   2225 C CA  . TRP A 1 312 ? 26.892  17.933  -11.715 1.000 13.536 0 312 TRP A CA  1 ? 
ATOM   2226 C C   . TRP A 1 312 ? 28.379  17.647  -11.613 1.000 13.103 0 312 TRP A C   1 ? 
ATOM   2227 O O   . TRP A 1 312 ? 29.195  18.502  -11.942 1.000 13.891 0 312 TRP A O   1 ? 
ATOM   2228 C CB  . TRP A 1 312 ? 26.456  17.947  -13.184 1.000 13.077 0 312 TRP A CB  1 ? 
ATOM   2229 C CG  . TRP A 1 312 ? 24.987  17.702  -13.389 1.000 13.475 0 312 TRP A CG  1 ? 
ATOM   2230 C CD1 . TRP A 1 312 ? 24.015  18.572  -13.809 1.000 13.897 0 312 TRP A CD1 1 ? 
ATOM   2231 C CD2 . TRP A 1 312 ? 24.345  16.414  -13.264 1.000 12.645 0 312 TRP A CD2 1 ? 
ATOM   2232 N NE1 . TRP A 1 312 ? 22.841  17.909  -13.953 1.000 14.746 0 312 TRP A NE1 1 ? 
ATOM   2233 C CE2 . TRP A 1 312 ? 22.996  16.594  -13.623 1.000 13.788 0 312 TRP A CE2 1 ? 
ATOM   2234 C CE3 . TRP A 1 312 ? 24.783  15.135  -12.906 1.000 12.248 0 312 TRP A CE3 1 ? 
ATOM   2235 C CZ2 . TRP A 1 312 ? 22.095  15.543  -13.633 1.000 14.556 0 312 TRP A CZ2 1 ? 
ATOM   2236 C CZ3 . TRP A 1 312 ? 23.888  14.088  -12.905 1.000 12.920 0 312 TRP A CZ3 1 ? 
ATOM   2237 C CH2 . TRP A 1 312 ? 22.549  14.294  -13.276 1.000 14.061 0 312 TRP A CH2 1 ? 
ATOM   2238 N N   . THR A 1 313 ? 28.711  16.427  -11.198 1.000 11.894 0 313 THR A N   1 ? 
ATOM   2239 C CA  . THR A 1 313 ? 30.054  15.984  -10.904 1.000 11.713 0 313 THR A CA  1 ? 
ATOM   2240 C C   . THR A 1 313 ? 30.282  14.632  -11.536 1.000 12.747 0 313 THR A C   1 ? 
ATOM   2241 O O   . THR A 1 313 ? 29.421  13.717  -11.416 1.000 12.664 0 313 THR A O   1 ? 
ATOM   2242 C CB  . THR A 1 313 ? 30.279  15.953  -9.384  1.000 13.564 0 313 THR A CB  1 ? 
ATOM   2243 O OG1 . THR A 1 313 ? 29.876  17.219  -8.858  1.000 14.291 0 313 THR A OG1 1 ? 
ATOM   2244 C CG2 . THR A 1 313 ? 31.710  15.668  -9.012  1.000 14.958 0 313 THR A CG2 1 ? 
ATOM   2245 N N   . SER A 1 314 ? 31.399  14.511  -12.251 1.000 12.453 0 314 SER A N   1 ? 
ATOM   2246 C CA  . SER A 1 314 ? 31.693  13.275  -12.952 1.000 11.592 0 314 SER A CA  1 ? 
ATOM   2247 C C   . SER A 1 314 ? 32.402  12.270  -12.070 1.000 13.511 0 314 SER A C   1 ? 
ATOM   2248 O O   . SER A 1 314 ? 33.349  12.640  -11.378 1.000 14.742 0 314 SER A O   1 ? 
ATOM   2249 C CB  . SER A 1 314 ? 32.508  13.533  -14.175 1.000 12.934 0 314 SER A CB  1 ? 
ATOM   2250 O OG  . SER A 1 314 ? 32.909  12.299  -14.740 1.000 14.395 0 314 SER A OG  1 ? 
ATOM   2251 N N   . LEU A 1 315 ? 31.978  10.997  -12.175 1.000 12.313 0 315 LEU A N   1 ? 
ATOM   2252 C CA  . LEU A 1 315 ? 32.716  9.865   -11.614 1.000 13.681 0 315 LEU A CA  1 ? 
ATOM   2253 C C   . LEU A 1 315 ? 33.419  9.059   -12.711 1.000 14.018 0 315 LEU A C   1 ? 
ATOM   2254 O O   . LEU A 1 315 ? 33.882  7.934   -12.464 1.000 14.501 0 315 LEU A O   1 ? 
ATOM   2255 C CB  . LEU A 1 315 ? 31.751  8.998   -10.788 1.000 15.222 0 315 LEU A CB  1 ? 
ATOM   2256 C CG  . LEU A 1 315 ? 31.315  9.553   -9.438  1.000 16.678 0 315 LEU A CG  1 ? 
ATOM   2257 C CD1 . LEU A 1 315 ? 30.117  8.767   -8.895  1.000 16.957 0 315 LEU A CD1 1 ? 
ATOM   2258 C CD2 . LEU A 1 315 ? 32.471  9.522   -8.432  1.000 18.541 0 315 LEU A CD2 1 ? 
ATOM   2259 N N   A SER A 1 316 ? 33.497  9.613   -13.921 0.600 13.260 0 316 SER A N   1 ? 
ATOM   2260 N N   B SER A 1 316 ? 33.544  9.641   -13.909 0.400 13.051 0 316 SER A N   1 ? 
ATOM   2261 C CA  A SER A 1 316 ? 34.228  9.000   -15.016 0.600 14.497 0 316 SER A CA  1 ? 
ATOM   2262 C CA  B SER A 1 316 ? 34.254  9.019   -15.016 0.400 13.556 0 316 SER A CA  1 ? 
ATOM   2263 C C   A SER A 1 316 ? 33.628  7.649   -15.395 0.600 13.090 0 316 SER A C   1 ? 
ATOM   2264 C C   B SER A 1 316 ? 33.662  7.640   -15.307 0.400 12.948 0 316 SER A C   1 ? 
ATOM   2265 O O   A SER A 1 316 ? 32.426  7.453   -15.303 0.600 13.150 0 316 SER A O   1 ? 
ATOM   2266 O O   B SER A 1 316 ? 32.497  7.411   -15.009 0.400 12.627 0 316 SER A O   1 ? 
ATOM   2267 C CB  A SER A 1 316 ? 35.697  8.895   -14.677 0.600 17.830 0 316 SER A CB  1 ? 
ATOM   2268 C CB  B SER A 1 316 ? 35.749  8.984   -14.747 0.400 15.068 0 316 SER A CB  1 ? 
ATOM   2269 O OG  A SER A 1 316 ? 36.476  8.775   -15.861 0.600 18.551 0 316 SER A OG  1 ? 
ATOM   2270 O OG  B SER A 1 316 ? 36.284  10.297  -14.613 0.400 14.171 0 316 SER A OG  1 ? 
ATOM   2271 N N   . GLY A 1 317 ? 34.479  6.725   -15.852 1.000 14.204 0 317 GLY A N   1 ? 
ATOM   2272 C CA  . GLY A 1 317 ? 33.986  5.479   -16.411 1.000 14.666 0 317 GLY A CA  1 ? 
ATOM   2273 C C   . GLY A 1 317 ? 33.431  5.649   -17.819 1.000 13.715 0 317 GLY A C   1 ? 
ATOM   2274 O O   . GLY A 1 317 ? 33.300  6.750   -18.346 1.000 15.176 0 317 GLY A O   1 ? 
ATOM   2275 N N   . VAL A 1 318 ? 33.220  4.504   -18.463 1.000 13.959 0 318 VAL A N   1 ? 
ATOM   2276 C CA  . VAL A 1 318 ? 32.563  4.413   -19.748 1.000 15.167 0 318 VAL A CA  1 ? 
ATOM   2277 C C   . VAL A 1 318 ? 31.481  3.355   -19.589 1.000 15.889 0 318 VAL A C   1 ? 
ATOM   2278 O O   . VAL A 1 318 ? 31.800  2.189   -19.393 1.000 17.254 0 318 VAL A O   1 ? 
ATOM   2279 C CB  . VAL A 1 318 ? 33.540  4.032   -20.874 1.000 19.700 0 318 VAL A CB  1 ? 
ATOM   2280 C CG1 . VAL A 1 318 ? 32.852  3.877   -22.208 1.000 21.710 0 318 VAL A CG1 1 ? 
ATOM   2281 C CG2 . VAL A 1 318 ? 34.674  5.058   -20.986 1.000 21.968 0 318 VAL A CG2 1 ? 
ATOM   2282 N N   . ILE A 1 319 ? 30.225  3.789   -19.641 1.000 13.496 0 319 ILE A N   1 ? 
ATOM   2283 C CA  . ILE A 1 319 ? 29.111  2.911   -19.334 1.000 13.096 0 319 ILE A CA  1 ? 
ATOM   2284 C C   . ILE A 1 319 ? 28.134  2.829   -20.500 1.000 13.626 0 319 ILE A C   1 ? 
ATOM   2285 O O   . ILE A 1 319 ? 28.015  3.763   -21.297 1.000 14.275 0 319 ILE A O   1 ? 
ATOM   2286 C CB  . ILE A 1 319 ? 28.459  3.266   -17.990 1.000 12.709 0 319 ILE A CB  1 ? 
ATOM   2287 C CG1 . ILE A 1 319 ? 27.782  4.640   -17.979 1.000 13.529 0 319 ILE A CG1 1 ? 
ATOM   2288 C CG2 . ILE A 1 319 ? 29.471  3.093   -16.862 1.000 13.873 0 319 ILE A CG2 1 ? 
ATOM   2289 C CD1 . ILE A 1 319 ? 26.983  4.993   -16.709 1.000 13.283 0 319 ILE A CD1 1 ? 
ATOM   2290 N N   . THR A 1 320 ? 27.425  1.700   -20.574 1.000 13.197 0 320 THR A N   1 ? 
ATOM   2291 C CA  . THR A 1 320 ? 26.533  1.376   -21.682 1.000 13.222 0 320 THR A CA  1 ? 
ATOM   2292 C C   . THR A 1 320 ? 25.120  1.025   -21.192 1.000 13.635 0 320 THR A C   1 ? 
ATOM   2293 O O   . THR A 1 320 ? 24.361  0.292   -21.838 1.000 15.542 0 320 THR A O   1 ? 
ATOM   2294 C CB  . THR A 1 320 ? 27.134  0.259   -22.559 1.000 15.393 0 320 THR A CB  1 ? 
ATOM   2295 O OG1 . THR A 1 320 ? 27.219  -0.925  -21.760 1.000 14.780 0 320 THR A OG1 1 ? 
ATOM   2296 C CG2 . THR A 1 320 ? 28.478  0.643   -23.165 1.000 15.803 0 320 THR A CG2 1 ? 
ATOM   2297 N N   . SER A 1 321 ? 24.787  1.479   -19.989 1.000 12.234 0 321 SER A N   1 ? 
ATOM   2298 C CA  . SER A 1 321 ? 23.450  1.358   -19.430 1.000 12.327 0 321 SER A CA  1 ? 
ATOM   2299 C C   . SER A 1 321 ? 23.215  2.536   -18.495 1.000 11.840 0 321 SER A C   1 ? 
ATOM   2300 O O   . SER A 1 321 ? 24.156  3.258   -18.135 1.000 12.623 0 321 SER A O   1 ? 
ATOM   2301 C CB  . SER A 1 321 ? 23.261  0.043   -18.670 1.000 12.255 0 321 SER A CB  1 ? 
ATOM   2302 O OG  . SER A 1 321 ? 23.999  0.027   -17.460 1.000 13.055 0 321 SER A OG  1 ? 
ATOM   2303 N N   . ALA A 1 322 ? 21.972  2.661   -18.016 1.000 11.245 0 322 ALA A N   1 ? 
ATOM   2304 C CA  . ALA A 1 322 ? 21.734  3.453   -16.833 1.000 11.461 0 322 ALA A CA  1 ? 
ATOM   2305 C C   . ALA A 1 322 ? 22.457  2.833   -15.645 1.000 12.104 0 322 ALA A C   1 ? 
ATOM   2306 O O   . ALA A 1 322 ? 22.622  1.610   -15.569 1.000 12.052 0 322 ALA A O   1 ? 
ATOM   2307 C CB  . ALA A 1 322 ? 20.288  3.619   -16.545 1.000 11.924 0 322 ALA A CB  1 ? 
ATOM   2308 N N   . PRO A 1 323 ? 22.850  3.662   -14.675 1.000 11.238 0 323 PRO A N   1 ? 
ATOM   2309 C CA  . PRO A 1 323 ? 23.305  3.154   -13.381 1.000 11.370 0 323 PRO A CA  1 ? 
ATOM   2310 C C   . PRO A 1 323 ? 22.184  2.597   -12.512 1.000 11.838 0 323 PRO A C   1 ? 
ATOM   2311 O O   . PRO A 1 323 ? 21.048  2.993   -12.632 1.000 12.305 0 323 PRO A O   1 ? 
ATOM   2312 C CB  . PRO A 1 323 ? 23.935  4.365   -12.715 1.000 11.045 0 323 PRO A CB  1 ? 
ATOM   2313 C CG  . PRO A 1 323 ? 23.189  5.528   -13.289 1.000 12.155 0 323 PRO A CG  1 ? 
ATOM   2314 C CD  . PRO A 1 323 ? 22.777  5.129   -14.689 1.000 11.375 0 323 PRO A CD  1 ? 
ATOM   2315 N N   . THR A 1 324 ? 22.573  1.617   -11.683 1.000 10.845 0 324 THR A N   1 ? 
ATOM   2316 C CA  . THR A 1 324 ? 21.771  1.111   -10.579 1.000 11.177 0 324 THR A CA  1 ? 
ATOM   2317 C C   . THR A 1 324 ? 22.497  1.427   -9.283  1.000 11.671 0 324 THR A C   1 ? 
ATOM   2318 O O   . THR A 1 324 ? 23.689  1.088   -9.180  1.000 12.058 0 324 THR A O   1 ? 
ATOM   2319 C CB  . THR A 1 324 ? 21.570  -0.398  -10.741 1.000 12.519 0 324 THR A CB  1 ? 
ATOM   2320 O OG1 . THR A 1 324 ? 20.894  -0.714  -11.980 1.000 13.266 0 324 THR A OG1 1 ? 
ATOM   2321 C CG2 . THR A 1 324 ? 20.753  -0.958  -9.601  1.000 14.110 0 324 THR A CG2 1 ? 
ATOM   2322 N N   . VAL A 1 325 ? 21.800  2.041   -8.326  1.000 12.888 0 325 VAL A N   1 ? 
ATOM   2323 C CA  . VAL A 1 325 ? 22.457  2.470   -7.100  1.000 12.617 0 325 VAL A CA  1 ? 
ATOM   2324 C C   . VAL A 1 325 ? 21.909  1.652   -5.947  1.000 12.441 0 325 VAL A C   1 ? 
ATOM   2325 O O   . VAL A 1 325 ? 20.700  1.468   -5.848  1.000 14.631 0 325 VAL A O   1 ? 
ATOM   2326 C CB  . VAL A 1 325 ? 22.235  3.981   -6.874  1.000 14.861 0 325 VAL A CB  1 ? 
ATOM   2327 C CG1 . VAL A 1 325 ? 23.020  4.442   -5.659  1.000 14.979 0 325 VAL A CG1 1 ? 
ATOM   2328 C CG2 . VAL A 1 325 ? 22.571  4.784   -8.120  1.000 19.267 0 325 VAL A CG2 1 ? 
ATOM   2329 N N   . ALA A 1 326 ? 22.832  1.184   -5.095  1.000 11.762 0 326 ALA A N   1 ? 
ATOM   2330 C CA  . ALA A 1 326 ? 22.479  0.474   -3.883  1.000 13.090 0 326 ALA A CA  1 ? 
ATOM   2331 C C   . ALA A 1 326 ? 23.271  1.052   -2.727  1.000 12.302 0 326 ALA A C   1 ? 
ATOM   2332 O O   . ALA A 1 326 ? 24.074  1.956   -2.889  1.000 13.447 0 326 ALA A O   1 ? 
ATOM   2333 C CB  . ALA A 1 326 ? 22.801  -0.986  -4.052  1.000 13.758 0 326 ALA A CB  1 ? 
ATOM   2334 N N   . LYS A 1 327 ? 23.049  0.475   -1.547  1.000 13.092 0 327 LYS A N   1 ? 
ATOM   2335 C CA  . LYS A 1 327 ? 23.726  0.904   -0.339  1.000 15.307 0 327 LYS A CA  1 ? 
ATOM   2336 C C   . LYS A 1 327 ? 24.211  -0.311  0.432   1.000 15.569 0 327 LYS A C   1 ? 
ATOM   2337 O O   . LYS A 1 327 ? 23.468  -1.256  0.633   1.000 15.747 0 327 LYS A O   1 ? 
ATOM   2338 C CB  . LYS A 1 327 ? 22.755  1.720   0.518   1.000 19.373 0 327 LYS A CB  1 ? 
ATOM   2339 C CG  . LYS A 1 327 ? 23.378  2.253   1.812   1.000 20.923 0 327 LYS A CG  1 ? 
ATOM   2340 C CD  . LYS A 1 327 ? 22.441  3.186   2.602   1.000 24.288 0 327 LYS A CD  1 ? 
ATOM   2341 C CE  . LYS A 1 327 ? 22.363  4.581   2.006   1.000 26.692 0 327 LYS A CE  1 ? 
ATOM   2342 N NZ  . LYS A 1 327 ? 21.334  5.393   2.709   1.000 30.592 0 327 LYS A NZ  1 ? 
ATOM   2343 N N   . ASN A 1 328 ? 25.492  -0.285  0.831   1.000 16.326 0 328 ASN A N   1 ? 
ATOM   2344 C CA  . ASN A 1 328 ? 26.047  -1.343  1.677   1.000 16.328 0 328 ASN A CA  1 ? 
ATOM   2345 C C   . ASN A 1 328 ? 25.557  -1.244  3.123   1.000 17.107 0 328 ASN A C   1 ? 
ATOM   2346 O O   . ASN A 1 328 ? 25.022  -0.226  3.533   1.000 16.752 0 328 ASN A O   1 ? 
ATOM   2347 C CB  . ASN A 1 328 ? 27.568  -1.265  1.628   1.000 17.895 0 328 ASN A CB  1 ? 
ATOM   2348 C CG  . ASN A 1 328 ? 28.055  -1.805  0.332   1.000 19.813 0 328 ASN A CG  1 ? 
ATOM   2349 O OD1 . ASN A 1 328 ? 28.129  -3.018  0.179   1.000 19.582 0 328 ASN A OD1 1 ? 
ATOM   2350 N ND2 . ASN A 1 328 ? 28.321  -0.915  -0.614  1.000 21.515 0 328 ASN A ND2 1 ? 
ATOM   2351 N N   . SER A 1 329 ? 25.772  -2.328  3.898   1.000 18.883 0 329 SER A N   1 ? 
ATOM   2352 C CA  . SER A 1 329 ? 25.372  -2.364  5.304   1.000 22.196 0 329 SER A CA  1 ? 
ATOM   2353 C C   . SER A 1 329 ? 26.058  -1.252  6.098   1.000 21.972 0 329 SER A C   1 ? 
ATOM   2354 O O   . SER A 1 329 ? 25.465  -0.686  7.003   1.000 24.497 0 329 SER A O   1 ? 
ATOM   2355 C CB  . SER A 1 329 ? 25.614  -3.734  5.926   1.000 24.148 0 329 SER A CB  1 ? 
ATOM   2356 O OG  . SER A 1 329 ? 26.922  -4.179  5.642   1.000 33.926 0 329 SER A OG  1 ? 
ATOM   2357 N N   . ASP A 1 330 ? 27.263  -0.858  5.712   1.000 21.590 0 330 ASP A N   1 ? 
ATOM   2358 C CA  . ASP A 1 330 ? 27.962  0.240   6.383   1.000 19.749 0 330 ASP A CA  1 ? 
ATOM   2359 C C   . ASP A 1 330 ? 27.437  1.629   6.011   1.000 21.700 0 330 ASP A C   1 ? 
ATOM   2360 O O   . ASP A 1 330 ? 27.973  2.615   6.514   1.000 22.440 0 330 ASP A O   1 ? 
ATOM   2361 C CB  . ASP A 1 330 ? 29.455  0.163   6.154   1.000 21.521 0 330 ASP A CB  1 ? 
ATOM   2362 C CG  . ASP A 1 330 ? 29.866  0.201   4.705   1.000 22.736 0 330 ASP A CG  1 ? 
ATOM   2363 O OD1 . ASP A 1 330 ? 30.988  -0.280  4.423   1.000 24.714 0 330 ASP A OD1 1 ? 
ATOM   2364 O OD2 . ASP A 1 330 ? 29.063  0.687   3.860   1.000 21.405 0 330 ASP A OD2 1 ? 
ATOM   2365 N N   . GLY A 1 331 ? 26.430  1.734   5.120   1.000 18.779 0 331 GLY A N   1 ? 
ATOM   2366 C CA  . GLY A 1 331 ? 25.853  3.019   4.777   1.000 18.765 0 331 GLY A CA  1 ? 
ATOM   2367 C C   . GLY A 1 331 ? 26.382  3.689   3.500   1.000 17.293 0 331 GLY A C   1 ? 
ATOM   2368 O O   . GLY A 1 331 ? 25.825  4.709   3.093   1.000 22.876 0 331 GLY A O   1 ? 
ATOM   2369 N N   . TRP A 1 332 ? 27.419  3.119   2.892   1.000 15.260 0 332 TRP A N   1 ? 
ATOM   2370 C CA  . TRP A 1 332 ? 28.085  3.723   1.737   1.000 15.541 0 332 TRP A CA  1 ? 
ATOM   2371 C C   . TRP A 1 332 ? 27.400  3.224   0.457   1.000 15.017 0 332 TRP A C   1 ? 
ATOM   2372 O O   . TRP A 1 332 ? 27.031  2.047   0.336   1.000 15.184 0 332 TRP A O   1 ? 
ATOM   2373 C CB  . TRP A 1 332 ? 29.588  3.432   1.700   1.000 18.394 0 332 TRP A CB  1 ? 
ATOM   2374 C CG  . TRP A 1 332 ? 30.355  3.901   2.912   1.000 19.938 0 332 TRP A CG  1 ? 
ATOM   2375 C CD1 . TRP A 1 332 ? 31.171  3.128   3.686   1.000 24.075 0 332 TRP A CD1 1 ? 
ATOM   2376 C CD2 . TRP A 1 332 ? 30.354  5.208   3.499   1.000 22.679 0 332 TRP A CD2 1 ? 
ATOM   2377 N NE1 . TRP A 1 332 ? 31.655  3.860   4.744   1.000 24.667 0 332 TRP A NE1 1 ? 
ATOM   2378 C CE2 . TRP A 1 332 ? 31.192  5.137   4.639   1.000 22.808 0 332 TRP A CE2 1 ? 
ATOM   2379 C CE3 . TRP A 1 332 ? 29.765  6.432   3.179   1.000 25.778 0 332 TRP A CE3 1 ? 
ATOM   2380 C CZ2 . TRP A 1 332 ? 31.437  6.243   5.456   1.000 26.309 0 332 TRP A CZ2 1 ? 
ATOM   2381 C CZ3 . TRP A 1 332 ? 30.030  7.526   3.976   1.000 25.856 0 332 TRP A CZ3 1 ? 
ATOM   2382 C CH2 . TRP A 1 332 ? 30.813  7.419   5.118   1.000 25.967 0 332 TRP A CH2 1 ? 
ATOM   2383 N N   . LEU A 1 333 ? 27.240  4.147   -0.486  1.000 13.103 0 333 LEU A N   1 ? 
ATOM   2384 C CA  . LEU A 1 333 ? 26.600  3.845   -1.766  1.000 13.499 0 333 LEU A CA  1 ? 
ATOM   2385 C C   . LEU A 1 333 ? 27.525  2.984   -2.620  1.000 13.826 0 333 LEU A C   1 ? 
ATOM   2386 O O   . LEU A 1 333 ? 28.765  2.968   -2.521  1.000 14.256 0 333 LEU A O   1 ? 
ATOM   2387 C CB  . LEU A 1 333 ? 26.200  5.135   -2.490  1.000 13.852 0 333 LEU A CB  1 ? 
ATOM   2388 C CG  . LEU A 1 333 ? 25.167  6.027   -1.787  1.000 14.613 0 333 LEU A CG  1 ? 
ATOM   2389 C CD1 . LEU A 1 333 ? 24.862  7.270   -2.615  1.000 16.541 0 333 LEU A CD1 1 ? 
ATOM   2390 C CD2 . LEU A 1 333 ? 23.876  5.293   -1.517  1.000 14.905 0 333 LEU A CD2 1 ? 
ATOM   2391 N N   . GLU A 1 334 ? 26.870  2.285   -3.540  1.000 13.393 0 334 GLU A N   1 ? 
ATOM   2392 C CA  . GLU A 1 334 ? 27.592  1.532   -4.540  1.000 13.710 0 334 GLU A CA  1 ? 
ATOM   2393 C C   . GLU A 1 334 ? 26.807  1.644   -5.843  1.000 12.811 0 334 GLU A C   1 ? 
ATOM   2394 O O   . GLU A 1 334 ? 25.568  1.523   -5.837  1.000 12.997 0 334 GLU A O   1 ? 
ATOM   2395 C CB  . GLU A 1 334 ? 27.753  0.092   -4.053  1.000 15.386 0 334 GLU A CB  1 ? 
ATOM   2396 C CG  . GLU A 1 334 ? 28.585  -0.805  -4.957  1.000 16.427 0 334 GLU A CG  1 ? 
ATOM   2397 C CD  . GLU A 1 334 ? 29.300  -1.974  -4.281  1.000 17.192 0 334 GLU A CD  1 ? 
ATOM   2398 O OE1 . GLU A 1 334 ? 29.325  -2.011  -3.062  1.000 18.600 0 334 GLU A OE1 1 ? 
ATOM   2399 O OE2 . GLU A 1 334 ? 29.908  -2.788  -4.987  1.000 18.427 0 334 GLU A OE2 1 ? 
ATOM   2400 N N   . VAL A 1 335 ? 27.510  1.840   -6.955  1.000 12.061 0 335 VAL A N   1 ? 
ATOM   2401 C CA  . VAL A 1 335 ? 26.858  2.032   -8.234  1.000 12.181 0 335 VAL A CA  1 ? 
ATOM   2402 C C   . VAL A 1 335 ? 27.367  0.989   -9.208  1.000 11.539 0 335 VAL A C   1 ? 
ATOM   2403 O O   . VAL A 1 335 ? 28.544  0.684   -9.278  1.000 12.107 0 335 VAL A O   1 ? 
ATOM   2404 C CB  . VAL A 1 335 ? 27.085  3.459   -8.792  1.000 12.610 0 335 VAL A CB  1 ? 
ATOM   2405 C CG1 . VAL A 1 335 ? 26.408  3.672   -10.128 1.000 14.027 0 335 VAL A CG1 1 ? 
ATOM   2406 C CG2 . VAL A 1 335 ? 26.622  4.476   -7.765  1.000 14.012 0 335 VAL A CG2 1 ? 
ATOM   2407 N N   . PHE A 1 336 ? 26.410  0.414   -9.938  1.000 11.719 0 336 PHE A N   1 ? 
ATOM   2408 C CA  . PHE A 1 336 ? 26.623  -0.615  -10.931 1.000 11.376 0 336 PHE A CA  1 ? 
ATOM   2409 C C   . PHE A 1 336 ? 26.166  -0.116  -12.293 1.000 12.209 0 336 PHE A C   1 ? 
ATOM   2410 O O   . PHE A 1 336 ? 25.151  0.559   -12.399 1.000 11.450 0 336 PHE A O   1 ? 
ATOM   2411 C CB  . PHE A 1 336 ? 25.796  -1.855  -10.592 1.000 11.862 0 336 PHE A CB  1 ? 
ATOM   2412 C CG  . PHE A 1 336 ? 26.075  -2.403  -9.215  1.000 11.317 0 336 PHE A CG  1 ? 
ATOM   2413 C CD1 . PHE A 1 336 ? 25.384  -1.954  -8.132  1.000 12.644 0 336 PHE A CD1 1 ? 
ATOM   2414 C CD2 . PHE A 1 336 ? 27.037  -3.389  -9.060  1.000 11.557 0 336 PHE A CD2 1 ? 
ATOM   2415 C CE1 . PHE A 1 336 ? 25.658  -2.456  -6.870  1.000 12.452 0 336 PHE A CE1 1 ? 
ATOM   2416 C CE2 . PHE A 1 336 ? 27.347  -3.874  -7.804  1.000 12.283 0 336 PHE A CE2 1 ? 
ATOM   2417 C CZ  . PHE A 1 336 ? 26.641  -3.434  -6.719  1.000 12.691 0 336 PHE A CZ  1 ? 
ATOM   2418 N N   . ALA A 1 337 ? 26.913  -0.451  -13.357 1.000 11.499 0 337 ALA A N   1 ? 
ATOM   2419 C CA  . ALA A 1 337 ? 26.490  -0.102  -14.701 1.000 12.622 0 337 ALA A CA  1 ? 
ATOM   2420 C C   . ALA A 1 337 ? 27.185  -1.034  -15.665 1.000 12.708 0 337 ALA A C   1 ? 
ATOM   2421 O O   . ALA A 1 337 ? 28.293  -1.466  -15.400 1.000 13.374 0 337 ALA A O   1 ? 
ATOM   2422 C CB  . ALA A 1 337 ? 26.821  1.357   -14.994 1.000 13.335 0 337 ALA A CB  1 ? 
ATOM   2423 N N   . ARG A 1 338 ? 26.571  -1.243  -16.826 1.000 12.150 0 338 ARG A N   1 ? 
ATOM   2424 C CA  . ARG A 1 338 ? 27.211  -2.076  -17.811 1.000 11.522 0 338 ARG A CA  1 ? 
ATOM   2425 C C   . ARG A 1 338 ? 28.401  -1.322  -18.406 1.000 12.110 0 338 ARG A C   1 ? 
ATOM   2426 O O   . ARG A 1 338 ? 28.321  -0.112  -18.617 1.000 13.084 0 338 ARG A O   1 ? 
ATOM   2427 C CB  . ARG A 1 338 ? 26.201  -2.462  -18.869 1.000 12.208 0 338 ARG A CB  1 ? 
ATOM   2428 C CG  . ARG A 1 338 ? 26.708  -3.627  -19.713 1.000 14.003 0 338 ARG A CG  1 ? 
ATOM   2429 C CD  . ARG A 1 338 ? 25.658  -4.129  -20.661 1.000 16.938 0 338 ARG A CD  1 ? 
ATOM   2430 N NE  . ARG A 1 338 ? 25.197  -3.071  -21.534 1.000 16.212 0 338 ARG A NE  1 ? 
ATOM   2431 C CZ  . ARG A 1 338 ? 24.371  -3.262  -22.550 1.000 20.044 0 338 ARG A CZ  1 ? 
ATOM   2432 N NH1 . ARG A 1 338 ? 23.883  -4.461  -22.820 1.000 17.778 0 338 ARG A NH1 1 ? 
ATOM   2433 N NH2 . ARG A 1 338 ? 24.020  -2.240  -23.301 1.000 19.762 0 338 ARG A NH2 1 ? 
ATOM   2434 N N   . GLY A 1 339 ? 29.492  -2.031  -18.711 1.000 12.822 0 339 GLY A N   1 ? 
ATOM   2435 C CA  . GLY A 1 339 ? 30.634  -1.440  -19.374 1.000 13.463 0 339 GLY A CA  1 ? 
ATOM   2436 C C   . GLY A 1 339 ? 30.648  -1.652  -20.871 1.000 15.279 0 339 GLY A C   1 ? 
ATOM   2437 O O   . GLY A 1 339 ? 29.743  -2.230  -21.449 1.000 16.804 0 339 GLY A O   1 ? 
ATOM   2438 N N   . ALA A 1 340 ? 31.737  -1.183  -21.479 1.000 18.287 0 340 ALA A N   1 ? 
ATOM   2439 C CA  . ALA A 1 340 ? 31.856  -1.180  -22.937 1.000 20.507 0 340 ALA A CA  1 ? 
ATOM   2440 C C   . ALA A 1 340 ? 31.887  -2.598  -23.529 1.000 21.935 0 340 ALA A C   1 ? 
ATOM   2441 O O   . ALA A 1 340 ? 31.518  -2.787  -24.692 1.000 26.436 0 340 ALA A O   1 ? 
ATOM   2442 C CB  . ALA A 1 340 ? 33.100  -0.381  -23.301 1.000 22.065 0 340 ALA A CB  1 ? 
ATOM   2443 N N   . ASN A 1 341 ? 32.302  -3.596  -22.726 1.000 20.332 0 341 ASN A N   1 ? 
ATOM   2444 C CA  . ASN A 1 341 ? 32.373  -4.993  -23.151 1.000 20.554 0 341 ASN A CA  1 ? 
ATOM   2445 C C   . ASN A 1 341 ? 31.201  -5.851  -22.619 1.000 19.226 0 341 ASN A C   1 ? 
ATOM   2446 O O   . ASN A 1 341 ? 31.269  -7.085  -22.651 1.000 17.412 0 341 ASN A O   1 ? 
ATOM   2447 C CB  . ASN A 1 341 ? 33.666  -5.605  -22.606 1.000 23.875 0 341 ASN A CB  1 ? 
ATOM   2448 C CG  . ASN A 1 341 ? 33.710  -5.530  -21.079 1.000 30.257 0 341 ASN A CG  1 ? 
ATOM   2449 O OD1 . ASN A 1 341 ? 32.856  -4.888  -20.443 1.000 26.905 0 341 ASN A OD1 1 ? 
ATOM   2450 N ND2 . ASN A 1 341 ? 34.720  -6.151  -20.462 1.000 30.519 0 341 ASN A ND2 1 ? 
ATOM   2451 N N   . ASN A 1 342 ? 30.164  -5.189  -22.083 1.000 16.547 0 342 ASN A N   1 ? 
ATOM   2452 C CA  . ASN A 1 342 ? 28.942  -5.805  -21.550 1.000 16.368 0 342 ASN A CA  1 ? 
ATOM   2453 C C   . ASN A 1 342 ? 29.112  -6.512  -20.205 1.000 14.597 0 342 ASN A C   1 ? 
ATOM   2454 O O   . ASN A 1 342 ? 28.196  -7.151  -19.733 1.000 13.904 0 342 ASN A O   1 ? 
ATOM   2455 C CB  . ASN A 1 342 ? 28.257  -6.700  -22.558 1.000 18.383 0 342 ASN A CB  1 ? 
ATOM   2456 C CG  . ASN A 1 342 ? 27.885  -5.899  -23.776 1.000 21.229 0 342 ASN A CG  1 ? 
ATOM   2457 O OD1 . ASN A 1 342 ? 27.303  -4.847  -23.637 1.000 20.853 0 342 ASN A OD1 1 ? 
ATOM   2458 N ND2 . ASN A 1 342 ? 28.275  -6.347  -24.959 1.000 30.137 0 342 ASN A ND2 1 ? 
ATOM   2459 N N   . ALA A 1 343 ? 30.255  -6.336  -19.592 1.000 12.624 0 343 ALA A N   1 ? 
ATOM   2460 C CA  . ALA A 1 343 ? 30.432  -6.765  -18.216 1.000 13.200 0 343 ALA A CA  1 ? 
ATOM   2461 C C   . ALA A 1 343 ? 29.745  -5.779  -17.279 1.000 13.747 0 343 ALA A C   1 ? 
ATOM   2462 O O   . ALA A 1 343 ? 29.431  -4.659  -17.635 1.000 14.472 0 343 ALA A O   1 ? 
ATOM   2463 C CB  . ALA A 1 343 ? 31.885  -6.904  -17.907 1.000 14.202 0 343 ALA A CB  1 ? 
ATOM   2464 N N   . LEU A 1 344 ? 29.486  -6.213  -16.049 1.000 13.444 0 344 LEU A N   1 ? 
ATOM   2465 C CA  . LEU A 1 344 ? 28.981  -5.321  -15.006 1.000 13.080 0 344 LEU A CA  1 ? 
ATOM   2466 C C   . LEU A 1 344 ? 30.153  -4.636  -14.323 1.000 14.107 0 344 LEU A C   1 ? 
ATOM   2467 O O   . LEU A 1 344 ? 30.984  -5.341  -13.738 1.000 15.353 0 344 LEU A O   1 ? 
ATOM   2468 C CB  . LEU A 1 344 ? 28.165  -6.078  -13.970 1.000 13.863 0 344 LEU A CB  1 ? 
ATOM   2469 C CG  . LEU A 1 344 ? 27.385  -5.170  -13.010 1.000 13.388 0 344 LEU A CG  1 ? 
ATOM   2470 C CD1 . LEU A 1 344 ? 26.372  -4.323  -13.733 1.000 15.047 0 344 LEU A CD1 1 ? 
ATOM   2471 C CD2 . LEU A 1 344 ? 26.720  -6.007  -11.924 1.000 14.874 0 344 LEU A CD2 1 ? 
ATOM   2472 N N   . CYS A 1 345 ? 30.184  -3.313  -14.390 1.000 13.892 0 345 CYS A N   1 ? 
ATOM   2473 C CA  . CYS A 1 345 ? 31.160  -2.519  -13.682 1.000 14.623 0 345 CYS A CA  1 ? 
ATOM   2474 C C   . CYS A 1 345 ? 30.565  -1.959  -12.393 1.000 13.154 0 345 CYS A C   1 ? 
ATOM   2475 O O   . CYS A 1 345 ? 29.343  -1.776  -12.283 1.000 13.487 0 345 CYS A O   1 ? 
ATOM   2476 C CB  . CYS A 1 345 ? 31.611  -1.394  -14.594 1.000 17.860 0 345 CYS A CB  1 ? 
ATOM   2477 S SG  . CYS A 1 345 ? 32.411  -2.053  -16.081 1.000 27.075 0 345 CYS A SG  1 ? 
ATOM   2478 N N   . HIS A 1 346 ? 31.440  -1.648  -11.438 1.000 13.252 0 346 HIS A N   1 ? 
ATOM   2479 C CA  . HIS A 1 346 ? 30.964  -1.034  -10.210 1.000 14.107 0 346 HIS A CA  1 ? 
ATOM   2480 C C   . HIS A 1 346 ? 32.007  -0.112  -9.601  1.000 13.317 0 346 HIS A C   1 ? 
ATOM   2481 O O   . HIS A 1 346 ? 33.205  -0.204  -9.884  1.000 13.927 0 346 HIS A O   1 ? 
ATOM   2482 C CB  . HIS A 1 346 ? 30.445  -2.025  -9.148  1.000 16.713 0 346 HIS A CB  1 ? 
ATOM   2483 C CG  . HIS A 1 346 ? 31.484  -2.858  -8.477  1.000 16.785 0 346 HIS A CG  1 ? 
ATOM   2484 N ND1 . HIS A 1 346 ? 31.342  -3.169  -7.136  1.000 17.173 0 346 HIS A ND1 1 ? 
ATOM   2485 C CD2 . HIS A 1 346 ? 32.597  -3.505  -8.913  1.000 20.243 0 346 HIS A CD2 1 ? 
ATOM   2486 C CE1 . HIS A 1 346 ? 32.356  -3.959  -6.780  1.000 20.734 0 346 HIS A CE1 1 ? 
ATOM   2487 N NE2 . HIS A 1 346 ? 33.136  -4.180  -7.834  1.000 19.024 0 346 HIS A NE2 1 ? 
ATOM   2488 N N   . ILE A 1 347 ? 31.478  0.833   -8.832  1.000 12.300 0 347 ILE A N   1 ? 
ATOM   2489 C CA  . ILE A 1 347 ? 32.255  1.858   -8.141  1.000 12.316 0 347 ILE A CA  1 ? 
ATOM   2490 C C   . ILE A 1 347 ? 31.609  2.022   -6.776  1.000 14.297 0 347 ILE A C   1 ? 
ATOM   2491 O O   . ILE A 1 347 ? 30.373  2.023   -6.699  1.000 14.473 0 347 ILE A O   1 ? 
ATOM   2492 C CB  . ILE A 1 347 ? 32.355  3.144   -9.000  1.000 13.429 0 347 ILE A CB  1 ? 
ATOM   2493 C CG1 . ILE A 1 347 ? 33.354  4.109   -8.366  1.000 14.855 0 347 ILE A CG1 1 ? 
ATOM   2494 C CG2 . ILE A 1 347 ? 31.002  3.818   -9.234  1.000 14.791 0 347 ILE A CG2 1 ? 
ATOM   2495 C CD1 . ILE A 1 347 ? 33.711  5.297   -9.235  1.000 15.852 0 347 ILE A CD1 1 ? 
ATOM   2496 N N   . GLN A 1 348 ? 32.422  2.118   -5.706  1.000 15.067 0 348 GLN A N   1 ? 
ATOM   2497 C CA  . GLN A 1 348 ? 31.959  2.091   -4.317  1.000 18.036 0 348 GLN A CA  1 ? 
ATOM   2498 C C   . GLN A 1 348 ? 32.320  3.436   -3.671  1.000 17.768 0 348 GLN A C   1 ? 
ATOM   2499 O O   . GLN A 1 348 ? 33.446  3.923   -3.805  1.000 17.065 0 348 GLN A O   1 ? 
ATOM   2500 C CB  . GLN A 1 348 ? 32.631  0.928   -3.562  1.000 21.097 0 348 GLN A CB  1 ? 
ATOM   2501 C CG  . GLN A 1 348 ? 31.902  0.525   -2.281  1.000 24.506 0 348 GLN A CG  1 ? 
ATOM   2502 C CD  . GLN A 1 348 ? 32.473  -0.720  -1.637  1.000 26.177 0 348 GLN A CD  1 ? 
ATOM   2503 O OE1 . GLN A 1 348 ? 33.587  -0.687  -1.120  1.000 27.204 0 348 GLN A OE1 1 ? 
ATOM   2504 N NE2 . GLN A 1 348 ? 31.713  -1.815  -1.641  1.000 25.802 0 348 GLN A NE2 1 ? 
ATOM   2505 N N   . GLN A 1 349 ? 31.387  4.022   -2.930  1.000 15.775 0 349 GLN A N   1 ? 
ATOM   2506 C CA  . GLN A 1 349 ? 31.727  5.109   -2.038  1.000 16.601 0 349 GLN A CA  1 ? 
ATOM   2507 C C   . GLN A 1 349 ? 32.574  4.605   -0.869  1.000 17.274 0 349 GLN A C   1 ? 
ATOM   2508 O O   . GLN A 1 349 ? 32.325  3.526   -0.341  1.000 17.460 0 349 GLN A O   1 ? 
ATOM   2509 C CB  . GLN A 1 349 ? 30.409  5.711   -1.601  1.000 19.464 0 349 GLN A CB  1 ? 
ATOM   2510 C CG  . GLN A 1 349 ? 30.580  6.841   -0.641  1.000 19.425 0 349 GLN A CG  1 ? 
ATOM   2511 C CD  . GLN A 1 349 ? 29.231  7.505   -0.455  1.000 21.817 0 349 GLN A CD  1 ? 
ATOM   2512 O OE1 . GLN A 1 349 ? 28.231  6.894   -0.068  1.000 16.674 0 349 GLN A OE1 1 ? 
ATOM   2513 N NE2 . GLN A 1 349 ? 29.204  8.797   -0.734  1.000 28.612 0 349 GLN A NE2 1 ? 
ATOM   2514 N N   . THR A 1 350 ? 33.579  5.399   -0.478  1.000 16.126 0 350 THR A N   1 ? 
ATOM   2515 C CA  . THR A 1 350 ? 34.432  5.046   0.649   1.000 17.475 0 350 THR A CA  1 ? 
ATOM   2516 C C   . THR A 1 350 ? 34.203  6.061   1.772   1.000 18.745 0 350 THR A C   1 ? 
ATOM   2517 O O   . THR A 1 350 ? 33.315  6.912   1.689   1.000 18.794 0 350 THR A O   1 ? 
ATOM   2518 C CB  . THR A 1 350 ? 35.895  4.976   0.188   1.000 21.092 0 350 THR A CB  1 ? 
ATOM   2519 O OG1 . THR A 1 350 ? 36.237  6.333   -0.130  1.000 23.404 0 350 THR A OG1 1 ? 
ATOM   2520 C CG2 . THR A 1 350 ? 36.052  4.044   -0.992  1.000 23.602 0 350 THR A CG2 1 ? 
ATOM   2521 N N   . THR A 1 351 ? 35.021  5.984   2.829   1.000 19.834 0 351 THR A N   1 ? 
ATOM   2522 C CA  . THR A 1 351 ? 34.800  6.897   3.932   1.000 20.728 0 351 THR A CA  1 ? 
ATOM   2523 C C   . THR A 1 351 ? 35.088  8.338   3.527   1.000 20.017 0 351 THR A C   1 ? 
ATOM   2524 O O   . THR A 1 351 ? 34.521  9.202   4.179   1.000 22.375 0 351 THR A O   1 ? 
ATOM   2525 C CB  . THR A 1 351 ? 35.588  6.503   5.190   1.000 22.165 0 351 THR A CB  1 ? 
ATOM   2526 O OG1 . THR A 1 351 ? 36.966  6.622   4.867   1.000 22.849 0 351 THR A OG1 1 ? 
ATOM   2527 C CG2 . THR A 1 351 ? 35.240  5.123   5.704   1.000 25.397 0 351 THR A CG2 1 ? 
ATOM   2528 N N   . SER A 1 352 ? 35.868  8.601   2.459   1.000 18.266 0 352 SER A N   1 ? 
ATOM   2529 C CA  . SER A 1 352 ? 36.189  9.982   2.099   1.000 19.525 0 352 SER A CA  1 ? 
ATOM   2530 C C   . SER A 1 352 ? 36.149  10.263  0.605   1.000 20.809 0 352 SER A C   1 ? 
ATOM   2531 O O   . SER A 1 352 ? 36.395  11.395  0.185   1.000 21.895 0 352 SER A O   1 ? 
ATOM   2532 C CB  . SER A 1 352 ? 37.509  10.411  2.688   1.000 20.951 0 352 SER A CB  1 ? 
ATOM   2533 O OG  . SER A 1 352 ? 38.554  9.624   2.166   1.000 23.550 0 352 SER A OG  1 ? 
ATOM   2534 N N   . SER A 1 353 ? 35.818  9.256   -0.206  1.000 19.007 0 353 SER A N   1 ? 
ATOM   2535 C CA  . SER A 1 353 ? 35.880  9.439   -1.644  1.000 18.602 0 353 SER A CA  1 ? 
ATOM   2536 C C   . SER A 1 353 ? 35.036  8.363   -2.310  1.000 17.634 0 353 SER A C   1 ? 
ATOM   2537 O O   . SER A 1 353 ? 34.045  7.891   -1.747  1.000 17.898 0 353 SER A O   1 ? 
ATOM   2538 C CB  . SER A 1 353 ? 37.340  9.460   -2.128  1.000 19.897 0 353 SER A CB  1 ? 
ATOM   2539 O OG  . SER A 1 353 ? 37.401  9.990   -3.455  1.000 22.696 0 353 SER A OG  1 ? 
ATOM   2540 N N   . TRP A 1 354 ? 35.349  8.097   -3.575  1.000 15.410 0 354 TRP A N   1 ? 
ATOM   2541 C CA  . TRP A 1 354 ? 34.867  6.933   -4.280  1.000 15.416 0 354 TRP A CA  1 ? 
ATOM   2542 C C   . TRP A 1 354 ? 36.064  6.099   -4.710  1.000 16.065 0 354 TRP A C   1 ? 
ATOM   2543 O O   . TRP A 1 354 ? 37.131  6.660   -4.936  1.000 18.363 0 354 TRP A O   1 ? 
ATOM   2544 C CB  . TRP A 1 354 ? 34.043  7.385   -5.498  1.000 15.323 0 354 TRP A CB  1 ? 
ATOM   2545 C CG  . TRP A 1 354 ? 32.683  7.927   -5.155  1.000 15.896 0 354 TRP A CG  1 ? 
ATOM   2546 C CD1 . TRP A 1 354 ? 32.408  9.171   -4.668  1.000 17.249 0 354 TRP A CD1 1 ? 
ATOM   2547 C CD2 . TRP A 1 354 ? 31.411  7.247   -5.222  1.000 14.795 0 354 TRP A CD2 1 ? 
ATOM   2548 N NE1 . TRP A 1 354 ? 31.057  9.321   -4.434  1.000 17.331 0 354 TRP A NE1 1 ? 
ATOM   2549 C CE2 . TRP A 1 354 ? 30.433  8.158   -4.765  1.000 16.028 0 354 TRP A CE2 1 ? 
ATOM   2550 C CE3 . TRP A 1 354 ? 31.013  5.981   -5.653  1.000 14.984 0 354 TRP A CE3 1 ? 
ATOM   2551 C CZ2 . TRP A 1 354 ? 29.075  7.828   -4.727  1.000 13.105 0 354 TRP A CZ2 1 ? 
ATOM   2552 C CZ3 . TRP A 1 354 ? 29.669  5.668   -5.623  1.000 14.499 0 354 TRP A CZ3 1 ? 
ATOM   2553 C CH2 . TRP A 1 354 ? 28.715  6.575   -5.160  1.000 13.915 0 354 TRP A CH2 1 ? 
ATOM   2554 N N   . SER A 1 355 ? 35.868  4.784   -4.862  1.000 14.091 0 355 SER A N   1 ? 
ATOM   2555 C CA  . SER A 1 355 ? 36.838  3.837   -5.347  1.000 14.770 0 355 SER A CA  1 ? 
ATOM   2556 C C   . SER A 1 355 ? 37.105  4.011   -6.833  1.000 14.065 0 355 SER A C   1 ? 
ATOM   2557 O O   . SER A 1 355 ? 36.447  4.805   -7.477  1.000 16.311 0 355 SER A O   1 ? 
ATOM   2558 C CB  . SER A 1 355 ? 36.389  2.427   -5.079  1.000 16.356 0 355 SER A CB  1 ? 
ATOM   2559 O OG  . SER A 1 355 ? 35.291  2.055   -5.929  1.000 15.754 0 355 SER A OG  1 ? 
ATOM   2560 N N   . THR A 1 356 ? 38.037  3.204   -7.346  1.000 15.362 0 356 THR A N   1 ? 
ATOM   2561 C CA  . THR A 1 356 ? 38.198  2.988   -8.761  1.000 15.630 0 356 THR A CA  1 ? 
ATOM   2562 C C   . THR A 1 356 ? 36.979  2.203   -9.269  1.000 15.078 0 356 THR A C   1 ? 
ATOM   2563 O O   . THR A 1 356 ? 36.266  1.526   -8.513  1.000 15.657 0 356 THR A O   1 ? 
ATOM   2564 C CB  . THR A 1 356 ? 39.475  2.188   -9.073  1.000 18.059 0 356 THR A CB  1 ? 
ATOM   2565 O OG1 . THR A 1 356 ? 39.399  0.895   -8.464  1.000 21.583 0 356 THR A OG1 1 ? 
ATOM   2566 C CG2 . THR A 1 356 ? 40.734  2.889   -8.618  1.000 20.422 0 356 THR A CG2 1 ? 
ATOM   2567 N N   . TRP A 1 357 ? 36.759  2.304   -10.572 1.000 15.213 0 357 TRP A N   1 ? 
ATOM   2568 C CA  . TRP A 1 357 ? 35.900  1.381   -11.301 1.000 13.915 0 357 TRP A CA  1 ? 
ATOM   2569 C C   . TRP A 1 357 ? 36.584  0.017   -11.420 1.000 15.497 0 357 TRP A C   1 ? 
ATOM   2570 O O   . TRP A 1 357 ? 37.733  -0.036  -11.825 1.000 15.642 0 357 TRP A O   1 ? 
ATOM   2571 C CB  . TRP A 1 357 ? 35.598  1.901   -12.706 1.000 14.537 0 357 TRP A CB  1 ? 
ATOM   2572 C CG  . TRP A 1 357 ? 34.601  3.020   -12.765 1.000 13.554 0 357 TRP A CG  1 ? 
ATOM   2573 C CD1 . TRP A 1 357 ? 34.845  4.357   -12.865 1.000 14.654 0 357 TRP A CD1 1 ? 
ATOM   2574 C CD2 . TRP A 1 357 ? 33.169  2.867   -12.780 1.000 13.029 0 357 TRP A CD2 1 ? 
ATOM   2575 N NE1 . TRP A 1 357 ? 33.659  5.027   -12.963 1.000 15.892 0 357 TRP A NE1 1 ? 
ATOM   2576 C CE2 . TRP A 1 357 ? 32.608  4.157   -12.907 1.000 15.331 0 357 TRP A CE2 1 ? 
ATOM   2577 C CE3 . TRP A 1 357 ? 32.304  1.775   -12.704 1.000 13.857 0 357 TRP A CE3 1 ? 
ATOM   2578 C CZ2 . TRP A 1 357 ? 31.236  4.360   -12.984 1.000 16.583 0 357 TRP A CZ2 1 ? 
ATOM   2579 C CZ3 . TRP A 1 357 ? 30.949  1.975   -12.753 1.000 14.639 0 357 TRP A CZ3 1 ? 
ATOM   2580 C CH2 . TRP A 1 357 ? 30.421  3.258   -12.929 1.000 16.069 0 357 TRP A CH2 1 ? 
ATOM   2581 N N   . THR A 1 358 ? 35.852  -1.061  -11.126 1.000 13.672 0 358 THR A N   1 ? 
ATOM   2582 C CA  . THR A 1 358 ? 36.303  -2.419  -11.409 1.000 14.048 0 358 THR A CA  1 ? 
ATOM   2583 C C   . THR A 1 358 ? 35.186  -3.238  -12.025 1.000 14.641 0 358 THR A C   1 ? 
ATOM   2584 O O   . THR A 1 358 ? 34.024  -2.835  -12.017 1.000 15.318 0 358 THR A O   1 ? 
ATOM   2585 C CB  . THR A 1 358 ? 36.842  -3.138  -10.174 1.000 17.154 0 358 THR A CB  1 ? 
ATOM   2586 O OG1 . THR A 1 358 ? 35.775  -3.167  -9.235  1.000 17.951 0 358 THR A OG1 1 ? 
ATOM   2587 C CG2 . THR A 1 358 ? 38.045  -2.453  -9.574  1.000 18.864 0 358 THR A CG2 1 ? 
ATOM   2588 N N   . SER A 1 359 ? 35.558  -4.368  -12.620 1.000 14.823 0 359 SER A N   1 ? 
ATOM   2589 C CA  . SER A 1 359 ? 34.616  -5.239  -13.285 1.000 14.876 0 359 SER A CA  1 ? 
ATOM   2590 C C   . SER A 1 359 ? 34.241  -6.432  -12.415 1.000 15.746 0 359 SER A C   1 ? 
ATOM   2591 O O   . SER A 1 359 ? 35.107  -7.049  -11.790 1.000 17.662 0 359 SER A O   1 ? 
ATOM   2592 C CB  . SER A 1 359 ? 35.187  -5.691  -14.588 1.000 15.899 0 359 SER A CB  1 ? 
ATOM   2593 O OG  . SER A 1 359 ? 34.302  -6.578  -15.255 1.000 18.631 0 359 SER A OG  1 ? 
ATOM   2594 N N   . LEU A 1 360 ? 32.927  -6.753  -12.405 1.000 14.793 0 360 LEU A N   1 ? 
ATOM   2595 C CA  . LEU A 1 360 ? 32.390  -7.997  -11.874 1.000 15.903 0 360 LEU A CA  1 ? 
ATOM   2596 C C   . LEU A 1 360 ? 32.195  -9.021  -12.979 1.000 16.458 0 360 LEU A C   1 ? 
ATOM   2597 O O   . LEU A 1 360 ? 31.609  -10.097 -12.759 1.000 16.409 0 360 LEU A O   1 ? 
ATOM   2598 C CB  . LEU A 1 360 ? 31.068  -7.672  -11.164 1.000 17.942 0 360 LEU A CB  1 ? 
ATOM   2599 C CG  . LEU A 1 360 ? 31.234  -6.860  -9.893  1.000 19.860 0 360 LEU A CG  1 ? 
ATOM   2600 C CD1 . LEU A 1 360 ? 29.882  -6.524  -9.257  1.000 21.681 0 360 LEU A CD1 1 ? 
ATOM   2601 C CD2 . LEU A 1 360 ? 32.103  -7.598  -8.898  1.000 23.171 0 360 LEU A CD2 1 ? 
ATOM   2602 N N   . GLY A 1 361 ? 32.635  -8.717  -14.207 1.000 14.099 0 361 GLY A N   1 ? 
ATOM   2603 C CA  . GLY A 1 361 ? 32.488  -9.675  -15.278 1.000 14.436 0 361 GLY A CA  1 ? 
ATOM   2604 C C   . GLY A 1 361 ? 31.025  -9.854  -15.686 1.000 13.816 0 361 GLY A C   1 ? 
ATOM   2605 O O   . GLY A 1 361 ? 30.184  -8.972  -15.461 1.000 12.756 0 361 GLY A O   1 ? 
ATOM   2606 N N   . GLY A 1 362 ? 30.770  -11.022 -16.289 1.000 15.183 0 362 GLY A N   1 ? 
ATOM   2607 C CA  . GLY A 1 362 ? 29.471  -11.281 -16.893 1.000 13.484 0 362 GLY A CA  1 ? 
ATOM   2608 C C   . GLY A 1 362 ? 29.356  -10.742 -18.310 1.000 14.667 0 362 GLY A C   1 ? 
ATOM   2609 O O   . GLY A 1 362 ? 30.233  -10.034 -18.804 1.000 13.889 0 362 GLY A O   1 ? 
ATOM   2610 N N   . ASN A 1 363 ? 28.189  -11.053 -18.914 1.000 13.559 0 363 ASN A N   1 ? 
ATOM   2611 C CA  . ASN A 1 363 ? 27.854  -10.556 -20.220 1.000 14.700 0 363 ASN A CA  1 ? 
ATOM   2612 C C   . ASN A 1 363 ? 26.354  -10.301 -20.219 1.000 13.146 0 363 ASN A C   1 ? 
ATOM   2613 O O   . ASN A 1 363 ? 25.545  -11.251 -20.333 1.000 14.358 0 363 ASN A O   1 ? 
ATOM   2614 C CB  . ASN A 1 363 ? 28.285  -11.577 -21.278 1.000 15.420 0 363 ASN A CB  1 ? 
ATOM   2615 C CG  . ASN A 1 363 ? 28.119  -11.035 -22.677 1.000 21.421 0 363 ASN A CG  1 ? 
ATOM   2616 O OD1 . ASN A 1 363 ? 27.376  -10.081 -22.911 1.000 24.985 0 363 ASN A OD1 1 ? 
ATOM   2617 N ND2 . ASN A 1 363 ? 28.740  -11.735 -23.625 1.000 28.100 0 363 ASN A ND2 1 ? 
ATOM   2618 N N   . LEU A 1 364 ? 26.028  -9.035  -19.977 1.000 13.140 0 364 LEU A N   1 ? 
ATOM   2619 C CA  . LEU A 1 364 ? 24.660  -8.593  -19.737 1.000 11.703 0 364 LEU A CA  1 ? 
ATOM   2620 C C   . LEU A 1 364 ? 24.048  -8.034  -21.009 1.000 13.656 0 364 LEU A C   1 ? 
ATOM   2621 O O   . LEU A 1 364 ? 24.681  -7.286  -21.765 1.000 16.073 0 364 LEU A O   1 ? 
ATOM   2622 C CB  . LEU A 1 364 ? 24.601  -7.505  -18.667 1.000 12.795 0 364 LEU A CB  1 ? 
ATOM   2623 C CG  . LEU A 1 364 ? 24.875  -7.985  -17.251 1.000 13.250 0 364 LEU A CG  1 ? 
ATOM   2624 C CD1 . LEU A 1 364 ? 25.240  -6.809  -16.387 1.000 15.766 0 364 LEU A CD1 1 ? 
ATOM   2625 C CD2 . LEU A 1 364 ? 23.723  -8.745  -16.638 1.000 16.194 0 364 LEU A CD2 1 ? 
ATOM   2626 N N   . ILE A 1 365 ? 22.779  -8.338  -21.183 1.000 11.387 0 365 ILE A N   1 ? 
ATOM   2627 C CA  . ILE A 1 365 ? 22.016  -7.717  -22.239 1.000 13.379 0 365 ILE A CA  1 ? 
ATOM   2628 C C   . ILE A 1 365 ? 21.005  -6.781  -21.591 1.000 12.331 0 365 ILE A C   1 ? 
ATOM   2629 O O   . ILE A 1 365 ? 20.697  -6.871  -20.393 1.000 14.302 0 365 ILE A O   1 ? 
ATOM   2630 C CB  . ILE A 1 365 ? 21.342  -8.746  -23.157 1.000 13.398 0 365 ILE A CB  1 ? 
ATOM   2631 C CG1 . ILE A 1 365 ? 20.269  -9.569  -22.436 1.000 13.903 0 365 ILE A CG1 1 ? 
ATOM   2632 C CG2 . ILE A 1 365 ? 22.369  -9.591  -23.884 1.000 13.947 0 365 ILE A CG2 1 ? 
ATOM   2633 C CD1 . ILE A 1 365 ? 19.488  -10.529 -23.346 1.000 15.970 0 365 ILE A CD1 1 ? 
ATOM   2634 N N   . ASP A 1 366 ? 20.453  -5.923  -22.450 1.000 13.332 0 366 ASP A N   1 ? 
ATOM   2635 C CA  . ASP A 1 366 ? 19.314  -5.081  -22.082 1.000 13.202 0 366 ASP A CA  1 ? 
ATOM   2636 C C   . ASP A 1 366 ? 18.056  -5.761  -22.574 1.000 13.785 0 366 ASP A C   1 ? 
ATOM   2637 O O   . ASP A 1 366 ? 17.769  -5.707  -23.752 1.000 15.160 0 366 ASP A O   1 ? 
ATOM   2638 C CB  . ASP A 1 366 ? 19.465  -3.671  -22.660 1.000 14.487 0 366 ASP A CB  1 ? 
ATOM   2639 C CG  . ASP A 1 366 ? 18.275  -2.761  -22.398 1.000 14.660 0 366 ASP A CG  1 ? 
ATOM   2640 O OD1 . ASP A 1 366 ? 17.384  -3.129  -21.603 1.000 14.976 0 366 ASP A OD1 1 ? 
ATOM   2641 O OD2 . ASP A 1 366 ? 18.265  -1.680  -23.034 1.000 18.301 0 366 ASP A OD2 1 ? 
ATOM   2642 N N   . ALA A 1 367 ? 17.339  -6.441  -21.661 1.000 12.900 0 367 ALA A N   1 ? 
ATOM   2643 C CA  . ALA A 1 367 ? 16.094  -7.156  -21.961 1.000 13.915 0 367 ALA A CA  1 ? 
ATOM   2644 C C   . ALA A 1 367 ? 14.854  -6.326  -21.584 1.000 14.745 0 367 ALA A C   1 ? 
ATOM   2645 O O   . ALA A 1 367 ? 13.734  -6.828  -21.531 1.000 14.689 0 367 ALA A O   1 ? 
ATOM   2646 C CB  . ALA A 1 367 ? 16.125  -8.481  -21.251 1.000 14.555 0 367 ALA A CB  1 ? 
ATOM   2647 N N   . SER A 1 368 ? 15.017  -5.020  -21.371 1.000 12.903 0 368 SER A N   1 ? 
ATOM   2648 C CA  . SER A 1 368 ? 13.918  -4.159  -20.963 1.000 13.187 0 368 SER A CA  1 ? 
ATOM   2649 C C   . SER A 1 368 ? 12.707  -4.347  -21.861 1.000 14.003 0 368 SER A C   1 ? 
ATOM   2650 O O   . SER A 1 368 ? 12.817  -4.288  -23.088 1.000 14.969 0 368 SER A O   1 ? 
ATOM   2651 C CB  . SER A 1 368 ? 14.306  -2.701  -20.946 1.000 13.144 0 368 SER A CB  1 ? 
ATOM   2652 O OG  . SER A 1 368 ? 13.148  -1.931  -20.674 1.000 15.385 0 368 SER A OG  1 ? 
ATOM   2653 N N   . ALA A 1 369 ? 11.547  -4.495  -21.226 1.000 14.411 0 369 ALA A N   1 ? 
ATOM   2654 C CA  . ALA A 1 369 ? 10.298  -4.731  -21.929 1.000 16.374 0 369 ALA A CA  1 ? 
ATOM   2655 C C   . ALA A 1 369 ? 9.767   -3.445  -22.559 1.000 20.886 0 369 ALA A C   1 ? 
ATOM   2656 O O   . ALA A 1 369 ? 8.887   -3.539  -23.400 1.000 22.719 0 369 ALA A O   1 ? 
ATOM   2657 C CB  . ALA A 1 369 ? 9.272   -5.324  -20.990 1.000 15.771 0 369 ALA A CB  1 ? 
ATOM   2658 N N   . ILE A 1 370 ? 10.322  -2.281  -22.223 1.000 23.339 0 370 ILE A N   1 ? 
ATOM   2659 C CA  . ILE A 1 370 ? 9.996   -1.076  -22.992 1.000 28.646 0 370 ILE A CA  1 ? 
ATOM   2660 C C   . ILE A 1 370 ? 11.230  -0.523  -23.700 1.000 33.503 0 370 ILE A C   1 ? 
ATOM   2661 O O   . ILE A 1 370 ? 12.197  -0.191  -23.032 1.000 45.964 0 370 ILE A O   1 ? 
ATOM   2662 C CB  . ILE A 1 370 ? 9.348   -0.041  -22.071 1.000 32.370 0 370 ILE A CB  1 ? 
ATOM   2663 C CG1 . ILE A 1 370 ? 7.975   -0.542  -21.625 1.000 32.894 0 370 ILE A CG1 1 ? 
ATOM   2664 C CG2 . ILE A 1 370 ? 9.272   1.319   -22.772 1.000 34.911 0 370 ILE A CG2 1 ? 
ATOM   2665 C CD1 . ILE A 1 370 ? 7.109   0.499   -20.963 1.000 29.395 0 370 ILE A CD1 1 ? 
ATOM   2666 N N   . LYS A 1 371 ? 11.167  -0.422  -25.041 1.000 49.372 0 371 LYS A N   1 ? 
ATOM   2667 C CA  . LYS A 1 371 ? 12.175  0.244   -25.860 1.000 50.089 0 371 LYS A CA  1 ? 
ATOM   2668 C CB  . LYS A 1 371 ? 13.588  -0.287  -25.576 1.000 48.465 0 371 LYS A CB  1 ? 
ATOM   2669 C CG  . LYS A 1 371 ? 13.704  -1.804  -25.487 1.000 48.139 0 371 LYS A CG  1 ? 
ATOM   2670 C CD  . LYS A 1 371 ? 15.110  -2.344  -25.430 1.000 46.357 0 371 LYS A CD  1 ? 
ATOM   2671 C CE  . LYS A 1 371 ? 15.132  -3.832  -25.139 1.000 44.020 0 371 LYS A CE  1 ? 
ATOM   2672 N NZ  . LYS A 1 371 ? 16.229  -4.512  -25.860 1.000 46.125 0 371 LYS A NZ  1 ? 
HETATM 2673 C C1  . MFU B 2 .   ? 8.023   20.636  -19.423 1.000 15.683 0 401 MFU A C1  1 ? 
HETATM 2674 C C2  . MFU B 2 .   ? 8.943   20.898  -20.603 1.000 16.766 0 401 MFU A C2  1 ? 
HETATM 2675 C C3  . MFU B 2 .   ? 10.386  20.855  -20.175 1.000 15.158 0 401 MFU A C3  1 ? 
HETATM 2676 C C4  . MFU B 2 .   ? 10.677  19.538  -19.462 1.000 14.020 0 401 MFU A C4  1 ? 
HETATM 2677 C C5  . MFU B 2 .   ? 9.727   19.388  -18.290 1.000 13.839 0 401 MFU A C5  1 ? 
HETATM 2678 C C6  . MFU B 2 .   ? 9.862   18.094  -17.529 1.000 12.781 0 401 MFU A C6  1 ? 
HETATM 2679 O O1  . MFU B 2 .   ? 8.132   21.735  -18.570 1.000 15.900 0 401 MFU A O1  1 ? 
HETATM 2680 O O2  . MFU B 2 .   ? 8.623   22.173  -21.170 1.000 17.109 0 401 MFU A O2  1 ? 
HETATM 2681 O O3  . MFU B 2 .   ? 11.259  20.974  -21.298 1.000 16.828 0 401 MFU A O3  1 ? 
HETATM 2682 O O4  . MFU B 2 .   ? 10.596  18.478  -20.416 1.000 13.958 0 401 MFU A O4  1 ? 
HETATM 2683 O O5  . MFU B 2 .   ? 8.368   19.411  -18.770 1.000 13.673 0 401 MFU A O5  1 ? 
HETATM 2684 C CM  . MFU B 2 .   ? 7.209   21.690  -17.516 1.000 17.790 0 401 MFU A CM  1 ? 
HETATM 2685 C C1  . MFU C 2 .   ? -4.164  -10.257 -18.302 1.000 18.841 0 402 MFU A C1  1 ? 
HETATM 2686 C C2  . MFU C 2 .   ? -4.491  -9.363  -19.492 1.000 19.835 0 402 MFU A C2  1 ? 
HETATM 2687 C C3  . MFU C 2 .   ? -4.670  -7.919  -19.021 1.000 19.429 0 402 MFU A C3  1 ? 
HETATM 2688 C C4  . MFU C 2 .   ? -3.409  -7.510  -18.275 1.000 15.685 0 402 MFU A C4  1 ? 
HETATM 2689 C C5  . MFU C 2 .   ? -3.167  -8.455  -17.111 1.000 15.737 0 402 MFU A C5  1 ? 
HETATM 2690 C C6  . MFU C 2 .   ? -1.919  -8.173  -16.300 1.000 16.034 0 402 MFU A C6  1 ? 
HETATM 2691 O O1  . MFU C 2 .   ? -5.270  -10.267 -17.444 1.000 21.050 0 402 MFU A O1  1 ? 
HETATM 2692 O O2  . MFU C 2 .   ? -5.640  -9.844  -20.206 1.000 21.524 0 402 MFU A O2  1 ? 
HETATM 2693 O O3  . MFU C 2 .   ? -4.856  -7.032  -20.135 1.000 20.872 0 402 MFU A O3  1 ? 
HETATM 2694 O O4  . MFU C 2 .   ? -2.321  -7.549  -19.172 1.000 17.228 0 402 MFU A O4  1 ? 
HETATM 2695 O O5  . MFU C 2 .   ? -3.021  -9.807  -17.603 1.000 17.223 0 402 MFU A O5  1 ? 
HETATM 2696 C CM  . MFU C 2 .   ? -5.110  -11.188 -16.371 1.000 21.107 0 402 MFU A CM  1 ? 
HETATM 2697 C C1  . MFU D 2 .   ? 6.463   -17.569 -0.402  1.000 21.040 0 403 MFU A C1  1 ? 
HETATM 2698 C C2  . MFU D 2 .   ? 6.392   -16.208 -1.080  1.000 18.120 0 403 MFU A C2  1 ? 
HETATM 2699 C C3  . MFU D 2 .   ? 6.346   -16.330 -2.580  1.000 17.600 0 403 MFU A C3  1 ? 
HETATM 2700 C C4  . MFU D 2 .   ? 5.415   -17.421 -3.091  1.000 19.173 0 403 MFU A C4  1 ? 
HETATM 2701 C C5  . MFU D 2 .   ? 5.651   -18.698 -2.309  1.000 20.227 0 403 MFU A C5  1 ? 
HETATM 2702 C C6  . MFU D 2 .   ? 4.720   -19.789 -2.773  1.000 20.526 0 403 MFU A C6  1 ? 
HETATM 2703 O O1  . MFU D 2 .   ? 7.731   -18.123 -0.628  1.000 19.207 0 403 MFU A O1  1 ? 
HETATM 2704 O O2  . MFU D 2 .   ? 7.543   -15.416 -0.726  1.000 18.581 0 403 MFU A O2  1 ? 
HETATM 2705 O O3  . MFU D 2 .   ? 5.952   -15.047 -3.076  1.000 15.338 0 403 MFU A O3  1 ? 
HETATM 2706 O O4  . MFU D 2 .   ? 4.044   -17.013 -3.001  1.000 19.621 0 403 MFU A O4  1 ? 
HETATM 2707 O O5  . MFU D 2 .   ? 5.479   -18.452 -0.882  1.000 17.934 0 403 MFU A O5  1 ? 
HETATM 2708 C CM  . MFU D 2 .   ? 8.028   -19.178 0.307   1.000 21.672 0 403 MFU A CM  1 ? 
HETATM 2709 C C1  . MFU E 2 .   ? -4.712  -4.748  -0.527  1.000 39.079 0 404 MFU A C1  1 ? 
HETATM 2710 C C2  . MFU E 2 .   ? -3.734  -3.850  -1.294  1.000 37.848 0 404 MFU A C2  1 ? 
HETATM 2711 C C3  . MFU E 2 .   ? -3.930  -3.847  -2.828  1.000 32.837 0 404 MFU A C3  1 ? 
HETATM 2712 C C4  . MFU E 2 .   ? -5.403  -3.880  -3.278  1.000 36.054 0 404 MFU A C4  1 ? 
HETATM 2713 C C5  . MFU E 2 .   ? -6.192  -4.881  -2.433  1.000 36.268 0 404 MFU A C5  1 ? 
HETATM 2714 C C6  . MFU E 2 .   ? -7.680  -4.867  -2.708  1.000 37.110 0 404 MFU A C6  1 ? 
HETATM 2715 O O1  . MFU E 2 .   ? -4.275  -6.085  -0.622  1.000 39.860 0 404 MFU A O1  1 ? 
HETATM 2716 O O2  . MFU E 2 .   ? -2.390  -4.253  -1.061  1.000 39.104 0 404 MFU A O2  1 ? 
HETATM 2717 O O3  . MFU E 2 .   ? -3.296  -2.651  -3.319  1.000 26.158 0 404 MFU A O3  1 ? 
HETATM 2718 O O4  . MFU E 2 .   ? -6.002  -2.571  -3.222  1.000 38.639 0 404 MFU A O4  1 ? 
HETATM 2719 O O5  . MFU E 2 .   ? -6.034  -4.602  -1.017  1.000 39.082 0 404 MFU A O5  1 ? 
HETATM 2720 C CM  . MFU E 2 .   ? -5.071  -7.006  0.139   1.000 41.065 0 404 MFU A CM  1 ? 
HETATM 2721 C C1  . EDO F 3 .   ? 13.910  19.401  -2.177  1.000 23.162 0 405 EDO A C1  1 ? 
HETATM 2722 O O1  . EDO F 3 .   ? 13.420  18.113  -1.770  1.000 21.249 0 405 EDO A O1  1 ? 
HETATM 2723 C C2  . EDO F 3 .   ? 14.163  19.471  -3.617  1.000 21.424 0 405 EDO A C2  1 ? 
HETATM 2724 O O2  . EDO F 3 .   ? 15.127  18.532  -4.029  1.000 17.089 0 405 EDO A O2  1 ? 
HETATM 2725 C C1  . EDO G 3 .   ? 5.379   22.495  -14.151 1.000 23.404 0 406 EDO A C1  1 ? 
HETATM 2726 O O1  . EDO G 3 .   ? 4.784   21.619  -13.281 1.000 31.765 0 406 EDO A O1  1 ? 
HETATM 2727 C C2  . EDO G 3 .   ? 4.382   22.926  -15.101 1.000 24.801 0 406 EDO A C2  1 ? 
HETATM 2728 O O2  . EDO G 3 .   ? 4.520   24.264  -15.485 1.000 33.908 0 406 EDO A O2  1 ? 
HETATM 2729 C C1  . EDO H 3 .   ? -2.268  6.993   -16.560 1.000 22.360 0 407 EDO A C1  1 ? 
HETATM 2730 O O1  . EDO H 3 .   ? -0.781  6.996   -16.449 1.000 33.558 0 407 EDO A O1  1 ? 
HETATM 2731 C C2  . EDO H 3 .   ? -2.980  8.281   -16.661 1.000 28.443 0 407 EDO A C2  1 ? 
HETATM 2732 O O2  . EDO H 3 .   ? -4.327  8.360   -17.269 1.000 33.569 0 407 EDO A O2  1 ? 
HETATM 2733 C C1  . PEG I 4 .   ? 9.224   -18.670 -19.046 1.000 30.335 0 408 PEG A C1  1 ? 
HETATM 2734 O O1  . PEG I 4 .   ? 10.209  -17.947 -19.811 1.000 27.248 0 408 PEG A O1  1 ? 
HETATM 2735 C C2  . PEG I 4 .   ? 9.729   -19.066 -17.675 1.000 33.583 0 408 PEG A C2  1 ? 
HETATM 2736 O O2  . PEG I 4 .   ? 10.463  -17.971 -17.137 1.000 35.322 0 408 PEG A O2  1 ? 
HETATM 2737 C C3  . PEG I 4 .   ? 11.309  -18.292 -16.047 1.000 34.216 0 408 PEG A C3  1 ? 
HETATM 2738 C C4  . PEG I 4 .   ? 12.074  -17.054 -15.671 1.000 37.005 0 408 PEG A C4  1 ? 
HETATM 2739 O O4  . PEG I 4 .   ? 12.859  -16.525 -16.711 1.000 33.338 0 408 PEG A O4  1 ? 
HETATM 2740 O O   . HOH J 5 .   ? -0.944  -2.120  -1.426  1.000 26.897 0 501 HOH A O   1 ? 
HETATM 2741 O O   . HOH J 5 .   ? 3.035   20.143  -12.448 1.000 26.357 0 502 HOH A O   1 ? 
HETATM 2742 O O   . HOH J 5 .   ? 8.489   21.809  3.223   1.000 38.161 0 503 HOH A O   1 ? 
HETATM 2743 O O   . HOH J 5 .   ? 0.353   19.254  -19.182 1.000 22.443 0 504 HOH A O   1 ? 
HETATM 2744 O O   . HOH J 5 .   ? 17.537  20.381  -1.886  1.000 32.500 0 505 HOH A O   1 ? 
HETATM 2745 O O   . HOH J 5 .   ? 25.736  8.855   -24.571 1.000 26.507 0 506 HOH A O   1 ? 
HETATM 2746 O O   . HOH J 5 .   ? 14.186  -3.739  -12.139 1.000 33.630 0 507 HOH A O   1 ? 
HETATM 2747 O O   . HOH J 5 .   ? 31.449  -0.597  1.982   1.000 28.407 0 508 HOH A O   1 ? 
HETATM 2748 O O   . HOH J 5 .   ? -1.511  15.837  -17.891 1.000 19.630 0 509 HOH A O   1 ? 
HETATM 2749 O O   . HOH J 5 .   ? 1.591   -2.430  -24.778 1.000 31.845 0 510 HOH A O   1 ? 
HETATM 2750 O O   . HOH J 5 .   ? 15.466  22.722  -8.658  1.000 21.621 0 511 HOH A O   1 ? 
HETATM 2751 O O   . HOH J 5 .   ? 1.610   11.425  -0.705  1.000 20.034 0 512 HOH A O   1 ? 
HETATM 2752 O O   . HOH J 5 .   ? 2.185   -8.091  9.206   1.000 34.997 0 513 HOH A O   1 ? 
HETATM 2753 O O   . HOH J 5 .   ? 17.378  -18.749 -21.527 1.000 28.657 0 514 HOH A O   1 ? 
HETATM 2754 O O   . HOH J 5 .   ? 15.703  23.892  -22.025 1.000 37.138 0 515 HOH A O   1 ? 
HETATM 2755 O O   . HOH J 5 .   ? 2.585   -18.587 -17.188 1.000 16.314 0 516 HOH A O   1 ? 
HETATM 2756 O O   . HOH J 5 .   ? 14.885  13.487  -24.933 1.000 26.580 0 517 HOH A O   1 ? 
HETATM 2757 O O   . HOH J 5 .   ? 39.794  8.273   3.972   1.000 31.641 0 518 HOH A O   1 ? 
HETATM 2758 O O   . HOH J 5 .   ? -4.021  11.430  -23.259 1.000 27.582 0 519 HOH A O   1 ? 
HETATM 2759 O O   . HOH J 5 .   ? 3.567   16.482  -22.222 1.000 28.574 0 520 HOH A O   1 ? 
HETATM 2760 O O   . HOH J 5 .   ? -5.029  -15.732 1.291   1.000 27.988 0 521 HOH A O   1 ? 
HETATM 2761 O O   . HOH J 5 .   ? 2.097   -12.918 -25.281 1.000 29.103 0 522 HOH A O   1 ? 
HETATM 2762 O O   . HOH J 5 .   ? 18.995  0.682   -0.317  1.000 31.104 0 523 HOH A O   1 ? 
HETATM 2763 O O   . HOH J 5 .   ? -4.142  10.255  -7.648  1.000 20.073 0 524 HOH A O   1 ? 
HETATM 2764 O O   . HOH J 5 .   ? 8.421   -11.283 -24.940 1.000 25.570 0 525 HOH A O   1 ? 
HETATM 2765 O O   . HOH J 5 .   ? 15.690  -3.776  -5.420  1.000 34.624 0 526 HOH A O   1 ? 
HETATM 2766 O O   . HOH J 5 .   ? 7.367   -10.189 2.322   1.000 14.858 0 527 HOH A O   1 ? 
HETATM 2767 O O   . HOH J 5 .   ? 24.053  23.555  -15.860 1.000 34.704 0 528 HOH A O   1 ? 
HETATM 2768 O O   . HOH J 5 .   ? 31.289  -4.610  -3.716  1.000 20.150 0 529 HOH A O   1 ? 
HETATM 2769 O O   . HOH J 5 .   ? 28.968  11.241  -3.421  1.000 28.500 0 530 HOH A O   1 ? 
HETATM 2770 O O   . HOH J 5 .   ? -7.772  -2.219  -17.499 1.000 15.397 0 531 HOH A O   1 ? 
HETATM 2771 O O   . HOH J 5 .   ? 1.450   -16.175 -23.666 1.000 26.149 0 532 HOH A O   1 ? 
HETATM 2772 O O   . HOH J 5 .   ? 19.984  -22.244 -18.150 1.000 26.939 0 533 HOH A O   1 ? 
HETATM 2773 O O   . HOH J 5 .   ? 16.883  22.644  -18.500 1.000 16.192 0 534 HOH A O   1 ? 
HETATM 2774 O O   . HOH J 5 .   ? 16.670  0.289   -22.343 1.000 20.072 0 535 HOH A O   1 ? 
HETATM 2775 O O   . HOH J 5 .   ? 22.044  -20.468 -17.842 1.000 15.506 0 536 HOH A O   1 ? 
HETATM 2776 O O   . HOH J 5 .   ? 18.511  27.222  2.432   1.000 26.727 0 537 HOH A O   1 ? 
HETATM 2777 O O   . HOH J 5 .   ? 33.151  1.411   0.987   1.000 35.153 0 538 HOH A O   1 ? 
HETATM 2778 O O   . HOH J 5 .   ? 7.143   -19.648 -23.632 1.000 32.409 0 539 HOH A O   1 ? 
HETATM 2779 O O   . HOH J 5 .   ? 30.493  -19.054 -6.487  1.000 24.473 0 540 HOH A O   1 ? 
HETATM 2780 O O   . HOH J 5 .   ? 31.703  19.229  -11.543 1.000 16.797 0 541 HOH A O   1 ? 
HETATM 2781 O O   . HOH J 5 .   ? 33.500  8.294   -20.515 1.000 36.474 0 542 HOH A O   1 ? 
HETATM 2782 O O   . HOH J 5 .   ? 35.406  -7.104  -17.616 1.000 26.800 0 543 HOH A O   1 ? 
HETATM 2783 O O   . HOH J 5 .   ? -7.202  2.304   -18.972 1.000 25.497 0 544 HOH A O   1 ? 
HETATM 2784 O O   . HOH J 5 .   ? 19.634  -1.396  -25.302 1.000 26.254 0 545 HOH A O   1 ? 
HETATM 2785 O O   . HOH J 5 .   ? 41.357  -0.857  -8.922  1.000 36.133 0 546 HOH A O   1 ? 
HETATM 2786 O O   . HOH J 5 .   ? 4.561   11.610  1.250   1.000 18.092 0 547 HOH A O   1 ? 
HETATM 2787 O O   . HOH J 5 .   ? 19.309  -0.817  -5.739  1.000 26.144 0 548 HOH A O   1 ? 
HETATM 2788 O O   . HOH J 5 .   ? 29.222  -14.231 4.781   1.000 28.144 0 549 HOH A O   1 ? 
HETATM 2789 O O   . HOH J 5 .   ? 19.940  -7.375  -17.862 1.000 12.035 0 550 HOH A O   1 ? 
HETATM 2790 O O   . HOH J 5 .   ? 33.585  12.743  -17.322 1.000 14.605 0 551 HOH A O   1 ? 
HETATM 2791 O O   . HOH J 5 .   ? 33.662  0.296   -19.826 1.000 22.422 0 552 HOH A O   1 ? 
HETATM 2792 O O   . HOH J 5 .   ? 10.827  8.172   -29.997 1.000 30.733 0 553 HOH A O   1 ? 
HETATM 2793 O O   . HOH J 5 .   ? -7.785  -10.603 -13.394 1.000 30.079 0 554 HOH A O   1 ? 
HETATM 2794 O O   . HOH J 5 .   ? 7.812   13.601  -30.791 1.000 24.122 0 555 HOH A O   1 ? 
HETATM 2795 O O   . HOH J 5 .   ? 30.663  18.947  -6.944  1.000 26.776 0 556 HOH A O   1 ? 
HETATM 2796 O O   . HOH J 5 .   ? 18.661  -12.699 2.641   1.000 14.112 0 557 HOH A O   1 ? 
HETATM 2797 O O   . HOH J 5 .   ? 33.847  9.385   6.786   1.000 25.842 0 558 HOH A O   1 ? 
HETATM 2798 O O   . HOH J 5 .   ? 37.364  6.227   -15.938 1.000 39.666 0 559 HOH A O   1 ? 
HETATM 2799 O O   . HOH J 5 .   ? -2.255  7.562   0.819   1.000 22.266 0 560 HOH A O   1 ? 
HETATM 2800 O O   . HOH J 5 .   ? 21.948  -12.463 -26.598 1.000 23.034 0 561 HOH A O   1 ? 
HETATM 2801 O O   . HOH J 5 .   ? -0.413  11.726  5.005   1.000 29.943 0 562 HOH A O   1 ? 
HETATM 2802 O O   . HOH J 5 .   ? 18.920  -11.869 -26.553 1.000 31.149 0 563 HOH A O   1 ? 
HETATM 2803 O O   . HOH J 5 .   ? 16.087  -11.737 -23.195 1.000 22.456 0 564 HOH A O   1 ? 
HETATM 2804 O O   . HOH J 5 .   ? 10.078  -1.022  -3.434  1.000 26.266 0 565 HOH A O   1 ? 
HETATM 2805 O O   . HOH J 5 .   ? 25.849  7.114   1.623   1.000 22.278 0 566 HOH A O   1 ? 
HETATM 2806 O O   . HOH J 5 .   ? 24.382  24.122  -3.539  1.000 28.828 0 567 HOH A O   1 ? 
HETATM 2807 O O   . HOH J 5 .   ? 17.000  -5.497  0.604   1.000 21.314 0 568 HOH A O   1 ? 
HETATM 2808 O O   . HOH J 5 .   ? 31.047  -9.446  -21.344 1.000 27.491 0 569 HOH A O   1 ? 
HETATM 2809 O O   . HOH J 5 .   ? 18.268  -0.060  -12.122 1.000 19.148 0 570 HOH A O   1 ? 
HETATM 2810 O O   . HOH J 5 .   ? 9.723   4.195   -14.301 1.000 15.443 0 571 HOH A O   1 ? 
HETATM 2811 O O   . HOH J 5 .   ? 21.762  -19.739 -8.787  1.000 23.980 0 572 HOH A O   1 ? 
HETATM 2812 O O   . HOH J 5 .   ? 17.261  -3.694  -18.859 1.000 16.733 0 573 HOH A O   1 ? 
HETATM 2813 O O   . HOH J 5 .   ? 20.722  -1.244  -1.212  1.000 15.813 0 574 HOH A O   1 ? 
HETATM 2814 O O   . HOH J 5 .   ? -4.933  1.817   -21.145 1.000 27.279 0 575 HOH A O   1 ? 
HETATM 2815 O O   . HOH J 5 .   ? -10.806 6.246   -7.385  1.000 30.943 0 576 HOH A O   1 ? 
HETATM 2816 O O   . HOH J 5 .   ? 13.844  3.194   -20.087 1.000 30.580 0 577 HOH A O   1 ? 
HETATM 2817 O O   . HOH J 5 .   ? 32.361  12.813  -7.041  1.000 24.879 0 578 HOH A O   1 ? 
HETATM 2818 O O   . HOH J 5 .   ? 21.014  -16.052 -3.341  1.000 14.294 0 579 HOH A O   1 ? 
HETATM 2819 O O   . HOH J 5 .   ? 11.427  2.919   -10.270 1.000 24.009 0 580 HOH A O   1 ? 
HETATM 2820 O O   . HOH J 5 .   ? -3.519  13.809  -4.369  1.000 29.503 0 581 HOH A O   1 ? 
HETATM 2821 O O   . HOH J 5 .   ? 8.003   24.236  -14.865 1.000 23.477 0 582 HOH A O   1 ? 
HETATM 2822 O O   . HOH J 5 .   ? 2.534   -18.254 -4.907  1.000 33.237 0 583 HOH A O   1 ? 
HETATM 2823 O O   . HOH J 5 .   ? 36.074  7.986   -10.835 1.000 27.144 0 584 HOH A O   1 ? 
HETATM 2824 O O   . HOH J 5 .   ? 20.926  21.022  -20.142 1.000 29.486 0 585 HOH A O   1 ? 
HETATM 2825 O O   . HOH J 5 .   ? 10.414  1.960   -12.691 1.000 16.084 0 586 HOH A O   1 ? 
HETATM 2826 O O   . HOH J 5 .   ? 2.604   20.534  -9.931  1.000 25.788 0 587 HOH A O   1 ? 
HETATM 2827 O O   . HOH J 5 .   ? 22.482  21.788  -12.057 1.000 18.277 0 588 HOH A O   1 ? 
HETATM 2828 O O   . HOH J 5 .   ? -2.069  -15.054 -11.213 1.000 23.190 0 589 HOH A O   1 ? 
HETATM 2829 O O   . HOH J 5 .   ? 0.054   17.089  -20.788 1.000 18.022 0 590 HOH A O   1 ? 
HETATM 2830 O O   . HOH J 5 .   ? 20.164  12.656  -24.046 1.000 30.130 0 591 HOH A O   1 ? 
HETATM 2831 O O   . HOH J 5 .   ? 23.165  -14.576 -1.242  1.000 16.586 0 592 HOH A O   1 ? 
HETATM 2832 O O   . HOH J 5 .   ? 16.964  17.091  1.732   1.000 35.817 0 593 HOH A O   1 ? 
HETATM 2833 O O   . HOH J 5 .   ? 2.838   9.793   -29.327 1.000 34.929 0 594 HOH A O   1 ? 
HETATM 2834 O O   . HOH J 5 .   ? -11.051 -1.483  -14.659 1.000 30.453 0 595 HOH A O   1 ? 
HETATM 2835 O O   . HOH J 5 .   ? -7.544  -6.811  -20.678 1.000 35.566 0 596 HOH A O   1 ? 
HETATM 2836 O O   . HOH J 5 .   ? 13.795  15.337  -26.456 1.000 27.522 0 597 HOH A O   1 ? 
HETATM 2837 O O   . HOH J 5 .   ? -0.735  -0.717  2.076   1.000 21.095 0 598 HOH A O   1 ? 
HETATM 2838 O O   . HOH J 5 .   ? 14.392  7.208   0.234   1.000 38.507 0 599 HOH A O   1 ? 
HETATM 2839 O O   . HOH J 5 .   ? 7.331   8.585   2.237   1.000 20.145 0 600 HOH A O   1 ? 
HETATM 2840 O O   . HOH J 5 .   ? 22.233  -0.940  -14.386 1.000 13.193 0 601 HOH A O   1 ? 
HETATM 2841 O O   . HOH J 5 .   ? 1.790   -0.082  2.637   1.000 18.264 0 602 HOH A O   1 ? 
HETATM 2842 O O   . HOH J 5 .   ? -8.763  0.347   -17.874 1.000 22.352 0 603 HOH A O   1 ? 
HETATM 2843 O O   . HOH J 5 .   ? -10.394 2.631   -6.209  1.000 22.914 0 604 HOH A O   1 ? 
HETATM 2844 O O   . HOH J 5 .   ? 14.942  18.534  0.778   1.000 25.905 0 605 HOH A O   1 ? 
HETATM 2845 O O   . HOH J 5 .   ? 32.095  -11.502 -10.424 1.000 20.986 0 606 HOH A O   1 ? 
HETATM 2846 O O   . HOH J 5 .   ? 35.187  -0.972  -7.650  1.000 21.616 0 607 HOH A O   1 ? 
HETATM 2847 O O   . HOH J 5 .   ? 4.887   23.053  2.805   1.000 21.616 0 608 HOH A O   1 ? 
HETATM 2848 O O   . HOH J 5 .   ? 19.155  -18.070 6.756   1.000 29.821 0 609 HOH A O   1 ? 
HETATM 2849 O O   . HOH J 5 .   ? 11.422  -4.398  -25.485 1.000 36.860 0 610 HOH A O   1 ? 
HETATM 2850 O O   . HOH J 5 .   ? 23.077  16.141  6.443   1.000 42.542 0 611 HOH A O   1 ? 
HETATM 2851 O O   . HOH J 5 .   ? 19.754  -22.181 -4.629  1.000 27.946 0 612 HOH A O   1 ? 
HETATM 2852 O O   . HOH J 5 .   ? 12.199  -3.939  -5.590  1.000 21.603 0 613 HOH A O   1 ? 
HETATM 2853 O O   . HOH J 5 .   ? 12.048  -4.755  -13.729 1.000 20.487 0 614 HOH A O   1 ? 
HETATM 2854 O O   . HOH J 5 .   ? -2.371  -15.470 -8.831  1.000 27.772 0 615 HOH A O   1 ? 
HETATM 2855 O O   . HOH J 5 .   ? 16.088  13.757  1.996   1.000 23.640 0 616 HOH A O   1 ? 
HETATM 2856 O O   . HOH J 5 .   ? -1.340  16.788  -7.164  1.000 31.780 0 617 HOH A O   1 ? 
HETATM 2857 O O   . HOH J 5 .   ? 18.349  2.450   -13.114 1.000 22.950 0 618 HOH A O   1 ? 
HETATM 2858 O O   . HOH J 5 .   ? 26.787  -4.606  2.203   1.000 16.695 0 619 HOH A O   1 ? 
HETATM 2859 O O   . HOH J 5 .   ? 0.230   -17.719 -5.683  1.000 34.300 0 620 HOH A O   1 ? 
HETATM 2860 O O   . HOH J 5 .   ? 22.895  -14.837 4.144   1.000 18.190 0 621 HOH A O   1 ? 
HETATM 2861 O O   . HOH J 5 .   ? 8.741   -14.044 -25.912 1.000 30.570 0 622 HOH A O   1 ? 
HETATM 2862 O O   . HOH J 5 .   ? 22.574  22.387  -9.451  1.000 22.607 0 623 HOH A O   1 ? 
HETATM 2863 O O   . HOH J 5 .   ? 0.370   16.141  -24.175 1.000 35.685 0 624 HOH A O   1 ? 
HETATM 2864 O O   . HOH J 5 .   ? -16.855 1.789   -5.118  1.000 31.079 0 625 HOH A O   1 ? 
HETATM 2865 O O   . HOH J 5 .   ? 14.524  6.229   -14.142 1.000 21.486 0 626 HOH A O   1 ? 
HETATM 2866 O O   . HOH J 5 .   ? 7.494   21.777  -23.721 1.000 27.689 0 627 HOH A O   1 ? 
HETATM 2867 O O   . HOH J 5 .   ? 8.051   24.569  -19.794 1.000 22.924 0 628 HOH A O   1 ? 
HETATM 2868 O O   . HOH J 5 .   ? 11.784  -0.107  -13.974 1.000 18.619 0 629 HOH A O   1 ? 
HETATM 2869 O O   . HOH J 5 .   ? -0.061  -2.686  4.701   1.000 29.072 0 630 HOH A O   1 ? 
HETATM 2870 O O   . HOH J 5 .   ? 10.534  -20.476 2.042   1.000 30.754 0 631 HOH A O   1 ? 
HETATM 2871 O O   . HOH J 5 .   ? 0.512   3.081   -24.199 1.000 35.335 0 632 HOH A O   1 ? 
HETATM 2872 O O   . HOH J 5 .   ? 32.982  -10.733 -18.813 1.000 34.138 0 633 HOH A O   1 ? 
HETATM 2873 O O   . HOH J 5 .   ? 5.997   -18.279 3.269   1.000 40.164 0 634 HOH A O   1 ? 
HETATM 2874 O O   . HOH J 5 .   ? 25.356  21.372  -12.456 1.000 26.300 0 635 HOH A O   1 ? 
HETATM 2875 O O   . HOH J 5 .   ? 38.510  3.933   -12.100 1.000 24.854 0 636 HOH A O   1 ? 
HETATM 2876 O O   . HOH J 5 .   ? 24.898  17.494  1.081   1.000 28.713 0 637 HOH A O   1 ? 
HETATM 2877 O O   . HOH J 5 .   ? 3.171   24.132  -7.319  1.000 26.424 0 638 HOH A O   1 ? 
HETATM 2878 O O   . HOH J 5 .   ? 32.200  9.894   -0.932  1.000 21.603 0 639 HOH A O   1 ? 
HETATM 2879 O O   . HOH J 5 .   ? 25.349  -21.180 -12.733 1.000 19.508 0 640 HOH A O   1 ? 
HETATM 2880 O O   . HOH J 5 .   ? 16.507  4.217   -11.705 1.000 19.474 0 641 HOH A O   1 ? 
HETATM 2881 O O   . HOH J 5 .   ? 12.780  21.038  -25.268 1.000 37.682 0 642 HOH A O   1 ? 
HETATM 2882 O O   . HOH J 5 .   ? 13.862  5.216   -5.187  1.000 31.728 0 643 HOH A O   1 ? 
HETATM 2883 O O   . HOH J 5 .   ? 10.338  -0.622  -6.747  1.000 21.480 0 644 HOH A O   1 ? 
HETATM 2884 O O   . HOH J 5 .   ? 21.760  -5.500  -24.952 1.000 24.120 0 645 HOH A O   1 ? 
HETATM 2885 O O   . HOH J 5 .   ? 27.317  -12.602 5.730   1.000 34.133 0 646 HOH A O   1 ? 
HETATM 2886 O O   . HOH J 5 .   ? 14.290  26.249  -7.545  1.000 34.911 0 647 HOH A O   1 ? 
HETATM 2887 O O   . HOH J 5 .   ? 13.166  -8.256  -23.949 1.000 24.856 0 648 HOH A O   1 ? 
HETATM 2888 O O   . HOH J 5 .   ? -3.013  -15.374 -15.961 1.000 21.311 0 649 HOH A O   1 ? 
HETATM 2889 O O   . HOH J 5 .   ? 32.077  9.504   1.842   1.000 26.961 0 650 HOH A O   1 ? 
HETATM 2890 O O   . HOH J 5 .   ? 17.448  -6.399  -18.785 1.000 14.285 0 651 HOH A O   1 ? 
HETATM 2891 O O   . HOH J 5 .   ? 13.721  25.138  -13.771 1.000 21.694 0 652 HOH A O   1 ? 
HETATM 2892 O O   . HOH J 5 .   ? 4.163   -22.086 -12.437 1.000 19.832 0 653 HOH A O   1 ? 
HETATM 2893 O O   . HOH J 5 .   ? -8.048  5.372   -16.860 1.000 26.945 0 654 HOH A O   1 ? 
HETATM 2894 O O   . HOH J 5 .   ? 16.369  1.759   -15.072 1.000 30.072 0 655 HOH A O   1 ? 
HETATM 2895 O O   . HOH J 5 .   ? 14.678  -5.313  -1.002  1.000 15.026 0 656 HOH A O   1 ? 
HETATM 2896 O O   . HOH J 5 .   ? 18.935  2.345   -8.622  1.000 15.460 0 657 HOH A O   1 ? 
HETATM 2897 O O   . HOH J 5 .   ? 9.764   1.612   -3.346  1.000 25.999 0 658 HOH A O   1 ? 
HETATM 2898 O O   . HOH J 5 .   ? 14.338  3.384   -14.781 1.000 29.735 0 659 HOH A O   1 ? 
HETATM 2899 O O   . HOH J 5 .   ? 14.077  -15.116 -23.421 1.000 24.920 0 660 HOH A O   1 ? 
HETATM 2900 O O   . HOH J 5 .   ? 38.414  -4.805  -12.905 1.000 29.251 0 661 HOH A O   1 ? 
HETATM 2901 O O   . HOH J 5 .   ? 9.148   -22.302 -0.922  1.000 29.178 0 662 HOH A O   1 ? 
HETATM 2902 O O   . HOH J 5 .   ? 33.071  16.878  -12.495 1.000 16.493 0 663 HOH A O   1 ? 
HETATM 2903 O O   . HOH J 5 .   ? 10.990  3.844   -6.671  1.000 19.489 0 664 HOH A O   1 ? 
HETATM 2904 O O   . HOH J 5 .   ? 30.128  -17.171 -14.095 1.000 24.985 0 665 HOH A O   1 ? 
HETATM 2905 O O   . HOH J 5 .   ? 19.027  7.209   -23.381 1.000 30.693 0 666 HOH A O   1 ? 
HETATM 2906 O O   . HOH J 5 .   ? 8.746   2.303   -0.722  1.000 17.978 0 667 HOH A O   1 ? 
HETATM 2907 O O   . HOH J 5 .   ? -5.217  15.672  -12.938 1.000 22.199 0 668 HOH A O   1 ? 
HETATM 2908 O O   . HOH J 5 .   ? 16.222  -21.307 -10.370 1.000 34.826 0 669 HOH A O   1 ? 
HETATM 2909 O O   . HOH J 5 .   ? -4.766  -13.361 -12.162 1.000 34.984 0 670 HOH A O   1 ? 
HETATM 2910 O O   . HOH J 5 .   ? 17.894  -2.071  -7.830  1.000 14.941 0 671 HOH A O   1 ? 
HETATM 2911 O O   . HOH J 5 .   ? 9.662   1.613   -8.265  1.000 18.115 0 672 HOH A O   1 ? 
HETATM 2912 O O   . HOH J 5 .   ? 8.740   -1.099  -1.045  1.000 27.551 0 673 HOH A O   1 ? 
HETATM 2913 O O   . HOH J 5 .   ? -1.945  15.085  -0.902  1.000 24.152 0 674 HOH A O   1 ? 
HETATM 2914 O O   . HOH J 5 .   ? -9.439  -5.611  -12.606 1.000 20.828 0 675 HOH A O   1 ? 
HETATM 2915 O O   . HOH J 5 .   ? -6.419  -10.324 -1.742  1.000 31.970 0 676 HOH A O   1 ? 
HETATM 2916 O O   . HOH J 5 .   ? 11.254  -2.849  -8.123  1.000 16.027 0 677 HOH A O   1 ? 
HETATM 2917 O O   . HOH J 5 .   ? -4.365  -9.616  1.569   1.000 37.584 0 678 HOH A O   1 ? 
HETATM 2918 O O   . HOH J 5 .   ? 1.020   13.887  6.084   1.000 27.644 0 679 HOH A O   1 ? 
HETATM 2919 O O   . HOH J 5 .   ? 28.087  5.531   5.951   1.000 37.220 0 680 HOH A O   1 ? 
HETATM 2920 O O   . HOH J 5 .   ? 34.450  -1.723  -5.087  1.000 27.155 0 681 HOH A O   1 ? 
HETATM 2921 O O   . HOH J 5 .   ? -0.129  19.162  -6.448  1.000 25.380 0 682 HOH A O   1 ? 
HETATM 2922 O O   . HOH J 5 .   ? 17.259  5.406   -0.789  1.000 24.720 0 683 HOH A O   1 ? 
HETATM 2923 O O   . HOH J 5 .   ? 13.740  -8.385  5.669   1.000 33.614 0 684 HOH A O   1 ? 
HETATM 2924 O O   . HOH J 5 .   ? 13.017  -23.190 -12.393 1.000 31.920 0 685 HOH A O   1 ? 
HETATM 2925 O O   . HOH J 5 .   ? 6.497   -5.168  -24.129 1.000 27.188 0 686 HOH A O   1 ? 
HETATM 2926 O O   . HOH J 5 .   ? 20.865  24.790  -6.267  1.000 32.963 0 687 HOH A O   1 ? 
HETATM 2927 O O   . HOH J 5 .   ? -8.531  7.607   -12.960 1.000 33.351 0 688 HOH A O   1 ? 
HETATM 2928 O O   . HOH J 5 .   ? -8.503  -16.708 -11.466 1.000 28.482 0 689 HOH A O   1 ? 
HETATM 2929 O O   . HOH J 5 .   ? 37.656  -0.558  -6.520  1.000 33.056 0 690 HOH A O   1 ? 
HETATM 2930 O O   . HOH J 5 .   ? 31.601  -15.078 -12.820 1.000 25.140 0 691 HOH A O   1 ? 
HETATM 2931 O O   . HOH J 5 .   ? 8.684   -5.974  -25.260 1.000 23.639 0 692 HOH A O   1 ? 
HETATM 2932 O O   . HOH J 5 .   ? 14.142  15.587  4.034   1.000 32.699 0 693 HOH A O   1 ? 
HETATM 2933 O O   . HOH J 5 .   ? -13.054 2.644   -6.629  1.000 26.169 0 694 HOH A O   1 ? 
HETATM 2934 O O   . HOH J 5 .   ? 17.015  4.469   -8.759  1.000 17.895 0 695 HOH A O   1 ? 
HETATM 2935 O O   . HOH J 5 .   ? 17.546  8.340   -25.611 1.000 28.871 0 696 HOH A O   1 ? 
HETATM 2936 O O   . HOH J 5 .   ? 23.253  -16.999 -2.357  1.000 30.315 0 697 HOH A O   1 ? 
HETATM 2937 O O   . HOH J 5 .   ? 15.374  4.164   -2.279  1.000 28.815 0 698 HOH A O   1 ? 
HETATM 2938 O O   . HOH J 5 .   ? 4.132   -19.322 -7.048  1.000 36.488 0 699 HOH A O   1 ? 
HETATM 2939 O O   . HOH J 5 .   ? 19.245  -1.944  -3.447  1.000 24.894 0 700 HOH A O   1 ? 
HETATM 2940 O O   . HOH J 5 .   ? 35.530  10.944  -17.859 1.000 21.615 0 701 HOH A O   1 ? 
HETATM 2941 O O   . HOH J 5 .   ? 23.181  4.213   -26.031 1.000 34.095 0 702 HOH A O   1 ? 
HETATM 2942 O O   . HOH J 5 .   ? 20.337  10.115  -25.036 1.000 42.752 0 703 HOH A O   1 ? 
HETATM 2943 O O   . HOH J 5 .   ? 21.969  -2.984  -25.584 1.000 36.957 0 704 HOH A O   1 ? 
HETATM 2944 O O   . HOH J 5 .   ? 14.413  0.253   -13.293 1.000 34.453 0 705 HOH A O   1 ? 
HETATM 2945 O O   . HOH J 5 .   ? 32.420  19.221  -8.881  1.000 27.428 0 706 HOH A O   1 ? 
HETATM 2946 O O   . HOH J 5 .   ? 20.674  -13.185 4.614   1.000 18.464 0 707 HOH A O   1 ? 
HETATM 2947 O O   . HOH J 5 .   ? 19.604  22.891  -19.076 1.000 26.723 0 708 HOH A O   1 ? 
HETATM 2948 O O   . HOH J 5 .   ? 33.410  -12.805 -17.125 1.000 31.651 0 709 HOH A O   1 ? 
HETATM 2949 O O   . HOH J 5 .   ? 18.231  23.440  -7.388  1.000 47.103 0 710 HOH A O   1 ? 
HETATM 2950 O O   . HOH J 5 .   ? 20.184  22.422  5.342   1.000 28.353 0 711 HOH A O   1 ? 
HETATM 2951 O O   . HOH J 5 .   ? 15.491  -24.649 -8.512  1.000 52.959 0 712 HOH A O   1 ? 
HETATM 2952 O O   . HOH J 5 .   ? 14.923  -3.592  -3.004  1.000 37.371 0 713 HOH A O   1 ? 
HETATM 2953 O O   . HOH J 5 .   ? 12.866  -1.687  -3.759  1.000 31.072 0 714 HOH A O   1 ? 
HETATM 2954 O O   . HOH J 5 .   ? 15.086  3.690   -7.192  1.000 24.939 0 715 HOH A O   1 ? 
HETATM 2955 O O   . HOH J 5 .   ? 13.264  -2.297  -9.863  1.000 31.086 0 716 HOH A O   1 ? 
HETATM 2956 O O   . HOH J 5 .   ? -9.926  -3.724  -16.954 1.000 27.510 0 717 HOH A O   1 ? 
HETATM 2957 O O   . HOH J 5 .   ? 15.728  25.055  -18.241 1.000 24.869 0 718 HOH A O   1 ? 
HETATM 2958 O O   . HOH J 5 .   ? -12.748 4.372   -8.724  1.000 30.496 0 719 HOH A O   1 ? 
HETATM 2959 O O   . HOH J 5 .   ? 14.734  26.084  -16.065 1.000 33.023 0 720 HOH A O   1 ? 
HETATM 2960 O O   . HOH J 5 .   ? 21.833  -16.752 -29.151 1.000 28.465 0 721 HOH A O   1 ? 
# 
