data_9OA4
# 
_entry.id   9OA4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9OA4         pdb_00009oa4 10.2210/pdb9oa4/pdb 
WWPDB D_1000294860 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9OA4 
_pdbx_database_status.recvd_initial_deposition_date   2025-04-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              gpoon@gsu.edu 
_pdbx_contact_author.name_first         Gregory 
_pdbx_contact_author.name_last          Poon 
_pdbx_contact_author.name_mi            MK 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5107-9458 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Terrell, J.R.' 1 0000-0001-5394-5663 
'Poon, G.M.K.'  2 0000-0001-5107-9458 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'DNA Recognition by ETS Proteins in UV Photodamage' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Sivapragasam, S.' 1 ?                   
primary 'Terrell, J.R.'    2 0000-0001-5394-5663 
primary 'Poon, G.M.K.'     3 ?                   
primary 'Wyrick, J.J.'     4 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer syn 
;DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3')
;
5036.292  1   ? ? ?                                 ? 
2 polymer syn 
;DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*TP*CP*GP*CP*TP*TP*AP*T)-3')
;
4775.103  1   ? ? ?                                 ? 
3 polymer man 'Transcription factor PU.1'                                      12436.583 1   ? ? 'ETS-Domain UNP residues 165-270' 
? 
4 water   nat water                                                            18.015    239 ? ? ?                                 
? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        '31 kDa-transforming protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polydeoxyribonucleotide no no '(DA)(DA)(DT)(DA)(DA)(DG)(DC)(DG)(DG)(DA)(DA)(DG)(DT)(DG)(DG)(DG)' AATAAGCGGAAGTGGG C ? 
2 polydeoxyribonucleotide no no '(DT)(DC)(DC)(DC)(DA)(DC)(DT)(DT)(DT)(DC)(DG)(DC)(DT)(DT)(DA)(DT)' TCCCACTTTCGCTTAT D ? 
3 'polypeptide(L)'        no no 
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
F ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   DA  n 
1 2   DA  n 
1 3   DT  n 
1 4   DA  n 
1 5   DA  n 
1 6   DG  n 
1 7   DC  n 
1 8   DG  n 
1 9   DG  n 
1 10  DA  n 
1 11  DA  n 
1 12  DG  n 
1 13  DT  n 
1 14  DG  n 
1 15  DG  n 
1 16  DG  n 
2 1   DT  n 
2 2   DC  n 
2 3   DC  n 
2 4   DC  n 
2 5   DA  n 
2 6   DC  n 
2 7   DT  n 
2 8   DT  n 
2 9   DT  n 
2 10  DC  n 
2 11  DG  n 
2 12  DC  n 
2 13  DT  n 
2 14  DT  n 
2 15  DA  n 
2 16  DT  n 
3 1   GLY n 
3 2   SER n 
3 3   LYS n 
3 4   LYS n 
3 5   LYS n 
3 6   ILE n 
3 7   ARG n 
3 8   LEU n 
3 9   TYR n 
3 10  GLN n 
3 11  PHE n 
3 12  LEU n 
3 13  LEU n 
3 14  ASP n 
3 15  LEU n 
3 16  LEU n 
3 17  ARG n 
3 18  SER n 
3 19  GLY n 
3 20  ASP n 
3 21  MET n 
3 22  LYS n 
3 23  ASP n 
3 24  SER n 
3 25  ILE n 
3 26  TRP n 
3 27  TRP n 
3 28  VAL n 
3 29  ASP n 
3 30  LYS n 
3 31  ASP n 
3 32  LYS n 
3 33  GLY n 
3 34  THR n 
3 35  PHE n 
3 36  GLN n 
3 37  PHE n 
3 38  SER n 
3 39  SER n 
3 40  LYS n 
3 41  HIS n 
3 42  LYS n 
3 43  GLU n 
3 44  ALA n 
3 45  LEU n 
3 46  ALA n 
3 47  HIS n 
3 48  ARG n 
3 49  TRP n 
3 50  GLY n 
3 51  ILE n 
3 52  GLN n 
3 53  LYS n 
3 54  GLY n 
3 55  ASN n 
3 56  ARG n 
3 57  LYS n 
3 58  LYS n 
3 59  MET n 
3 60  THR n 
3 61  TYR n 
3 62  GLN n 
3 63  LYS n 
3 64  MET n 
3 65  ALA n 
3 66  ARG n 
3 67  ALA n 
3 68  LEU n 
3 69  ARG n 
3 70  ASN n 
3 71  TYR n 
3 72  GLY n 
3 73  LYS n 
3 74  THR n 
3 75  GLY n 
3 76  GLU n 
3 77  VAL n 
3 78  LYS n 
3 79  LYS n 
3 80  VAL n 
3 81  LYS n 
3 82  LYS n 
3 83  LYS n 
3 84  LEU n 
3 85  THR n 
3 86  TYR n 
3 87  GLN n 
3 88  PHE n 
3 89  SER n 
3 90  GLY n 
3 91  GLU n 
3 92  VAL n 
3 93  LEU n 
3 94  GLY n 
3 95  ARG n 
3 96  GLY n 
3 97  GLY n 
3 98  LEU n 
3 99  ALA n 
3 100 GLU n 
3 101 ARG n 
3 102 ARG n 
3 103 HIS n 
3 104 PRO n 
3 105 PRO n 
3 106 HIS n 
# 
_entity_src_gen.entity_id                          3 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   106 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SPI1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
1 1 sample 1 16 'synthetic construct' ? 32630 ? 
2 1 sample 1 16 'synthetic construct' ? 32630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   DA  1   1   1   DA  DA  C . n 
A 1 2   DA  2   2   2   DA  DA  C . n 
A 1 3   DT  3   3   3   DT  DT  C . n 
A 1 4   DA  4   4   4   DA  DA  C . n 
A 1 5   DA  5   5   5   DA  DA  C . n 
A 1 6   DG  6   6   6   DG  DG  C . n 
A 1 7   DC  7   7   7   DC  DC  C . n 
A 1 8   DG  8   8   8   DG  DG  C . n 
A 1 9   DG  9   9   9   DG  DG  C . n 
A 1 10  DA  10  10  10  DA  DA  C . n 
A 1 11  DA  11  11  11  DA  DA  C . n 
A 1 12  DG  12  12  12  DG  DG  C . n 
A 1 13  DT  13  13  13  DT  DT  C . n 
A 1 14  DG  14  14  14  DG  DG  C . n 
A 1 15  DG  15  15  15  DG  DG  C . n 
A 1 16  DG  16  16  16  DG  DG  C . n 
B 2 1   DT  1   17  17  DT  DT  D . n 
B 2 2   DC  2   18  18  DC  DC  D . n 
B 2 3   DC  3   19  19  DC  DC  D . n 
B 2 4   DC  4   20  20  DC  DC  D . n 
B 2 5   DA  5   21  21  DA  DA  D . n 
B 2 6   DC  6   22  22  DC  DC  D . n 
B 2 7   DT  7   23  23  DT  DT  D . n 
B 2 8   DT  8   24  24  DT  DT  D . n 
B 2 9   DT  9   25  25  DT  DT  D . n 
B 2 10  DC  10  26  26  DC  DC  D . n 
B 2 11  DG  11  27  27  DG  DG  D . n 
B 2 12  DC  12  28  28  DC  DC  D . n 
B 2 13  DT  13  29  29  DT  DT  D . n 
B 2 14  DT  14  30  30  DT  DT  D . n 
B 2 15  DA  15  31  31  DA  DA  D . n 
B 2 16  DT  16  32  32  DT  DT  D . n 
C 3 1   GLY 1   165 ?   ?   ?   F . n 
C 3 2   SER 2   166 ?   ?   ?   F . n 
C 3 3   LYS 3   167 ?   ?   ?   F . n 
C 3 4   LYS 4   168 ?   ?   ?   F . n 
C 3 5   LYS 5   169 169 LYS LYS F . n 
C 3 6   ILE 6   170 170 ILE ILE F . n 
C 3 7   ARG 7   171 171 ARG ARG F . n 
C 3 8   LEU 8   172 172 LEU LEU F . n 
C 3 9   TYR 9   173 173 TYR TYR F . n 
C 3 10  GLN 10  174 174 GLN GLN F . n 
C 3 11  PHE 11  175 175 PHE PHE F . n 
C 3 12  LEU 12  176 176 LEU LEU F . n 
C 3 13  LEU 13  177 177 LEU LEU F . n 
C 3 14  ASP 14  178 178 ASP ASP F . n 
C 3 15  LEU 15  179 179 LEU LEU F . n 
C 3 16  LEU 16  180 180 LEU LEU F . n 
C 3 17  ARG 17  181 181 ARG ARG F . n 
C 3 18  SER 18  182 182 SER SER F . n 
C 3 19  GLY 19  183 183 GLY GLY F . n 
C 3 20  ASP 20  184 184 ASP ASP F . n 
C 3 21  MET 21  185 185 MET MET F . n 
C 3 22  LYS 22  186 186 LYS LYS F . n 
C 3 23  ASP 23  187 187 ASP ASP F . n 
C 3 24  SER 24  188 188 SER SER F . n 
C 3 25  ILE 25  189 189 ILE ILE F . n 
C 3 26  TRP 26  190 190 TRP TRP F . n 
C 3 27  TRP 27  191 191 TRP TRP F . n 
C 3 28  VAL 28  192 192 VAL VAL F . n 
C 3 29  ASP 29  193 193 ASP ASP F . n 
C 3 30  LYS 30  194 194 LYS LYS F . n 
C 3 31  ASP 31  195 195 ASP ASP F . n 
C 3 32  LYS 32  196 196 LYS LYS F . n 
C 3 33  GLY 33  197 197 GLY GLY F . n 
C 3 34  THR 34  198 198 THR THR F . n 
C 3 35  PHE 35  199 199 PHE PHE F . n 
C 3 36  GLN 36  200 200 GLN GLN F . n 
C 3 37  PHE 37  201 201 PHE PHE F . n 
C 3 38  SER 38  202 202 SER SER F . n 
C 3 39  SER 39  203 203 SER SER F . n 
C 3 40  LYS 40  204 204 LYS LYS F . n 
C 3 41  HIS 41  205 205 HIS HIS F . n 
C 3 42  LYS 42  206 206 LYS LYS F . n 
C 3 43  GLU 43  207 207 GLU GLU F . n 
C 3 44  ALA 44  208 208 ALA ALA F . n 
C 3 45  LEU 45  209 209 LEU LEU F . n 
C 3 46  ALA 46  210 210 ALA ALA F . n 
C 3 47  HIS 47  211 211 HIS HIS F . n 
C 3 48  ARG 48  212 212 ARG ARG F . n 
C 3 49  TRP 49  213 213 TRP TRP F . n 
C 3 50  GLY 50  214 214 GLY GLY F . n 
C 3 51  ILE 51  215 215 ILE ILE F . n 
C 3 52  GLN 52  216 216 GLN GLN F . n 
C 3 53  LYS 53  217 217 LYS LYS F . n 
C 3 54  GLY 54  218 218 GLY GLY F . n 
C 3 55  ASN 55  219 219 ASN ASN F . n 
C 3 56  ARG 56  220 220 ARG ARG F . n 
C 3 57  LYS 57  221 221 LYS LYS F . n 
C 3 58  LYS 58  222 222 LYS LYS F . n 
C 3 59  MET 59  223 223 MET MET F . n 
C 3 60  THR 60  224 224 THR THR F . n 
C 3 61  TYR 61  225 225 TYR TYR F . n 
C 3 62  GLN 62  226 226 GLN GLN F . n 
C 3 63  LYS 63  227 227 LYS LYS F . n 
C 3 64  MET 64  228 228 MET MET F . n 
C 3 65  ALA 65  229 229 ALA ALA F . n 
C 3 66  ARG 66  230 230 ARG ARG F . n 
C 3 67  ALA 67  231 231 ALA ALA F . n 
C 3 68  LEU 68  232 232 LEU LEU F . n 
C 3 69  ARG 69  233 233 ARG ARG F . n 
C 3 70  ASN 70  234 234 ASN ASN F . n 
C 3 71  TYR 71  235 235 TYR TYR F . n 
C 3 72  GLY 72  236 236 GLY GLY F . n 
C 3 73  LYS 73  237 237 LYS LYS F . n 
C 3 74  THR 74  238 238 THR THR F . n 
C 3 75  GLY 75  239 239 GLY GLY F . n 
C 3 76  GLU 76  240 240 GLU GLU F . n 
C 3 77  VAL 77  241 241 VAL VAL F . n 
C 3 78  LYS 78  242 242 LYS LYS F . n 
C 3 79  LYS 79  243 243 LYS LYS F . n 
C 3 80  VAL 80  244 244 VAL VAL F . n 
C 3 81  LYS 81  245 245 LYS LYS F . n 
C 3 82  LYS 82  246 246 LYS LYS F . n 
C 3 83  LYS 83  247 247 LYS LYS F . n 
C 3 84  LEU 84  248 248 LEU LEU F . n 
C 3 85  THR 85  249 249 THR THR F . n 
C 3 86  TYR 86  250 250 TYR TYR F . n 
C 3 87  GLN 87  251 251 GLN GLN F . n 
C 3 88  PHE 88  252 252 PHE PHE F . n 
C 3 89  SER 89  253 253 SER SER F . n 
C 3 90  GLY 90  254 254 GLY GLY F . n 
C 3 91  GLU 91  255 255 GLU GLU F . n 
C 3 92  VAL 92  256 256 VAL VAL F . n 
C 3 93  LEU 93  257 257 LEU LEU F . n 
C 3 94  GLY 94  258 258 GLY GLY F . n 
C 3 95  ARG 95  259 259 ARG ARG F . n 
C 3 96  GLY 96  260 ?   ?   ?   F . n 
C 3 97  GLY 97  261 ?   ?   ?   F . n 
C 3 98  LEU 98  262 ?   ?   ?   F . n 
C 3 99  ALA 99  263 ?   ?   ?   F . n 
C 3 100 GLU 100 264 ?   ?   ?   F . n 
C 3 101 ARG 101 265 ?   ?   ?   F . n 
C 3 102 ARG 102 266 ?   ?   ?   F . n 
C 3 103 HIS 103 267 ?   ?   ?   F . n 
C 3 104 PRO 104 268 ?   ?   ?   F . n 
C 3 105 PRO 105 269 ?   ?   ?   F . n 
C 3 106 HIS 106 270 ?   ?   ?   F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 HOH 1   101 83  HOH HOH C . 
D 4 HOH 2   102 95  HOH HOH C . 
D 4 HOH 3   103 193 HOH HOH C . 
D 4 HOH 4   104 50  HOH HOH C . 
D 4 HOH 5   105 76  HOH HOH C . 
D 4 HOH 6   106 79  HOH HOH C . 
D 4 HOH 7   107 22  HOH HOH C . 
D 4 HOH 8   108 65  HOH HOH C . 
D 4 HOH 9   109 27  HOH HOH C . 
D 4 HOH 10  110 86  HOH HOH C . 
D 4 HOH 11  111 175 HOH HOH C . 
D 4 HOH 12  112 11  HOH HOH C . 
D 4 HOH 13  113 158 HOH HOH C . 
D 4 HOH 14  114 21  HOH HOH C . 
D 4 HOH 15  115 37  HOH HOH C . 
D 4 HOH 16  116 209 HOH HOH C . 
D 4 HOH 17  117 41  HOH HOH C . 
D 4 HOH 18  118 57  HOH HOH C . 
D 4 HOH 19  119 61  HOH HOH C . 
D 4 HOH 20  120 96  HOH HOH C . 
D 4 HOH 21  121 16  HOH HOH C . 
D 4 HOH 22  122 19  HOH HOH C . 
D 4 HOH 23  123 88  HOH HOH C . 
D 4 HOH 24  124 49  HOH HOH C . 
D 4 HOH 25  125 109 HOH HOH C . 
D 4 HOH 26  126 129 HOH HOH C . 
D 4 HOH 27  127 163 HOH HOH C . 
D 4 HOH 28  128 17  HOH HOH C . 
D 4 HOH 29  129 73  HOH HOH C . 
D 4 HOH 30  130 67  HOH HOH C . 
D 4 HOH 31  131 148 HOH HOH C . 
D 4 HOH 32  132 141 HOH HOH C . 
D 4 HOH 33  133 232 HOH HOH C . 
D 4 HOH 34  134 90  HOH HOH C . 
D 4 HOH 35  135 25  HOH HOH C . 
D 4 HOH 36  136 52  HOH HOH C . 
D 4 HOH 37  137 198 HOH HOH C . 
D 4 HOH 38  138 66  HOH HOH C . 
D 4 HOH 39  139 100 HOH HOH C . 
D 4 HOH 40  140 201 HOH HOH C . 
D 4 HOH 41  141 82  HOH HOH C . 
D 4 HOH 42  142 144 HOH HOH C . 
D 4 HOH 43  143 103 HOH HOH C . 
D 4 HOH 44  144 74  HOH HOH C . 
D 4 HOH 45  145 240 HOH HOH C . 
D 4 HOH 46  146 127 HOH HOH C . 
D 4 HOH 47  147 121 HOH HOH C . 
D 4 HOH 48  148 160 HOH HOH C . 
D 4 HOH 49  149 167 HOH HOH C . 
D 4 HOH 50  150 195 HOH HOH C . 
D 4 HOH 51  151 128 HOH HOH C . 
D 4 HOH 52  152 92  HOH HOH C . 
D 4 HOH 53  153 235 HOH HOH C . 
D 4 HOH 54  154 108 HOH HOH C . 
D 4 HOH 55  155 219 HOH HOH C . 
D 4 HOH 56  156 159 HOH HOH C . 
D 4 HOH 57  157 150 HOH HOH C . 
D 4 HOH 58  158 228 HOH HOH C . 
D 4 HOH 59  159 241 HOH HOH C . 
D 4 HOH 60  160 138 HOH HOH C . 
D 4 HOH 61  161 194 HOH HOH C . 
D 4 HOH 62  162 145 HOH HOH C . 
D 4 HOH 63  163 136 HOH HOH C . 
D 4 HOH 64  164 172 HOH HOH C . 
D 4 HOH 65  165 226 HOH HOH C . 
E 4 HOH 1   101 131 HOH HOH D . 
E 4 HOH 2   102 229 HOH HOH D . 
E 4 HOH 3   103 4   HOH HOH D . 
E 4 HOH 4   104 60  HOH HOH D . 
E 4 HOH 5   105 133 HOH HOH D . 
E 4 HOH 6   106 98  HOH HOH D . 
E 4 HOH 7   107 190 HOH HOH D . 
E 4 HOH 8   108 91  HOH HOH D . 
E 4 HOH 9   109 69  HOH HOH D . 
E 4 HOH 10  110 42  HOH HOH D . 
E 4 HOH 11  111 12  HOH HOH D . 
E 4 HOH 12  112 239 HOH HOH D . 
E 4 HOH 13  113 137 HOH HOH D . 
E 4 HOH 14  114 62  HOH HOH D . 
E 4 HOH 15  115 5   HOH HOH D . 
E 4 HOH 16  116 56  HOH HOH D . 
E 4 HOH 17  117 3   HOH HOH D . 
E 4 HOH 18  118 13  HOH HOH D . 
E 4 HOH 19  119 202 HOH HOH D . 
E 4 HOH 20  120 196 HOH HOH D . 
E 4 HOH 21  121 8   HOH HOH D . 
E 4 HOH 22  122 81  HOH HOH D . 
E 4 HOH 23  123 236 HOH HOH D . 
E 4 HOH 24  124 87  HOH HOH D . 
E 4 HOH 25  125 7   HOH HOH D . 
E 4 HOH 26  126 6   HOH HOH D . 
E 4 HOH 27  127 114 HOH HOH D . 
E 4 HOH 28  128 168 HOH HOH D . 
E 4 HOH 29  129 153 HOH HOH D . 
E 4 HOH 30  130 134 HOH HOH D . 
E 4 HOH 31  131 2   HOH HOH D . 
E 4 HOH 32  132 115 HOH HOH D . 
E 4 HOH 33  133 33  HOH HOH D . 
E 4 HOH 34  134 122 HOH HOH D . 
E 4 HOH 35  135 39  HOH HOH D . 
E 4 HOH 36  136 117 HOH HOH D . 
E 4 HOH 37  137 31  HOH HOH D . 
E 4 HOH 38  138 142 HOH HOH D . 
E 4 HOH 39  139 93  HOH HOH D . 
E 4 HOH 40  140 58  HOH HOH D . 
E 4 HOH 41  141 105 HOH HOH D . 
E 4 HOH 42  142 143 HOH HOH D . 
E 4 HOH 43  143 46  HOH HOH D . 
E 4 HOH 44  144 124 HOH HOH D . 
E 4 HOH 45  145 55  HOH HOH D . 
E 4 HOH 46  146 197 HOH HOH D . 
E 4 HOH 47  147 180 HOH HOH D . 
E 4 HOH 48  148 135 HOH HOH D . 
E 4 HOH 49  149 162 HOH HOH D . 
E 4 HOH 50  150 47  HOH HOH D . 
E 4 HOH 51  151 206 HOH HOH D . 
E 4 HOH 52  152 208 HOH HOH D . 
E 4 HOH 53  153 213 HOH HOH D . 
E 4 HOH 54  154 24  HOH HOH D . 
E 4 HOH 55  155 63  HOH HOH D . 
E 4 HOH 56  156 221 HOH HOH D . 
E 4 HOH 57  157 104 HOH HOH D . 
E 4 HOH 58  158 212 HOH HOH D . 
F 4 HOH 1   301 28  HOH HOH F . 
F 4 HOH 2   302 214 HOH HOH F . 
F 4 HOH 3   303 147 HOH HOH F . 
F 4 HOH 4   304 192 HOH HOH F . 
F 4 HOH 5   305 130 HOH HOH F . 
F 4 HOH 6   306 200 HOH HOH F . 
F 4 HOH 7   307 234 HOH HOH F . 
F 4 HOH 8   308 53  HOH HOH F . 
F 4 HOH 9   309 34  HOH HOH F . 
F 4 HOH 10  310 174 HOH HOH F . 
F 4 HOH 11  311 207 HOH HOH F . 
F 4 HOH 12  312 125 HOH HOH F . 
F 4 HOH 13  313 64  HOH HOH F . 
F 4 HOH 14  314 89  HOH HOH F . 
F 4 HOH 15  315 15  HOH HOH F . 
F 4 HOH 16  316 54  HOH HOH F . 
F 4 HOH 17  317 181 HOH HOH F . 
F 4 HOH 18  318 176 HOH HOH F . 
F 4 HOH 19  319 171 HOH HOH F . 
F 4 HOH 20  320 179 HOH HOH F . 
F 4 HOH 21  321 26  HOH HOH F . 
F 4 HOH 22  322 72  HOH HOH F . 
F 4 HOH 23  323 119 HOH HOH F . 
F 4 HOH 24  324 1   HOH HOH F . 
F 4 HOH 25  325 78  HOH HOH F . 
F 4 HOH 26  326 40  HOH HOH F . 
F 4 HOH 27  327 84  HOH HOH F . 
F 4 HOH 28  328 139 HOH HOH F . 
F 4 HOH 29  329 23  HOH HOH F . 
F 4 HOH 30  330 102 HOH HOH F . 
F 4 HOH 31  331 59  HOH HOH F . 
F 4 HOH 32  332 80  HOH HOH F . 
F 4 HOH 33  333 224 HOH HOH F . 
F 4 HOH 34  334 51  HOH HOH F . 
F 4 HOH 35  335 120 HOH HOH F . 
F 4 HOH 36  336 35  HOH HOH F . 
F 4 HOH 37  337 70  HOH HOH F . 
F 4 HOH 38  338 71  HOH HOH F . 
F 4 HOH 39  339 154 HOH HOH F . 
F 4 HOH 40  340 146 HOH HOH F . 
F 4 HOH 41  341 36  HOH HOH F . 
F 4 HOH 42  342 164 HOH HOH F . 
F 4 HOH 43  343 99  HOH HOH F . 
F 4 HOH 44  344 211 HOH HOH F . 
F 4 HOH 45  345 75  HOH HOH F . 
F 4 HOH 46  346 215 HOH HOH F . 
F 4 HOH 47  347 237 HOH HOH F . 
F 4 HOH 48  348 140 HOH HOH F . 
F 4 HOH 49  349 220 HOH HOH F . 
F 4 HOH 50  350 184 HOH HOH F . 
F 4 HOH 51  351 32  HOH HOH F . 
F 4 HOH 52  352 18  HOH HOH F . 
F 4 HOH 53  353 45  HOH HOH F . 
F 4 HOH 54  354 233 HOH HOH F . 
F 4 HOH 55  355 111 HOH HOH F . 
F 4 HOH 56  356 29  HOH HOH F . 
F 4 HOH 57  357 218 HOH HOH F . 
F 4 HOH 58  358 225 HOH HOH F . 
F 4 HOH 59  359 38  HOH HOH F . 
F 4 HOH 60  360 126 HOH HOH F . 
F 4 HOH 61  361 230 HOH HOH F . 
F 4 HOH 62  362 14  HOH HOH F . 
F 4 HOH 63  363 20  HOH HOH F . 
F 4 HOH 64  364 9   HOH HOH F . 
F 4 HOH 65  365 238 HOH HOH F . 
F 4 HOH 66  366 68  HOH HOH F . 
F 4 HOH 67  367 10  HOH HOH F . 
F 4 HOH 68  368 222 HOH HOH F . 
F 4 HOH 69  369 85  HOH HOH F . 
F 4 HOH 70  370 204 HOH HOH F . 
F 4 HOH 71  371 123 HOH HOH F . 
F 4 HOH 72  372 77  HOH HOH F . 
F 4 HOH 73  373 48  HOH HOH F . 
F 4 HOH 74  374 30  HOH HOH F . 
F 4 HOH 75  375 43  HOH HOH F . 
F 4 HOH 76  376 110 HOH HOH F . 
F 4 HOH 77  377 169 HOH HOH F . 
F 4 HOH 78  378 44  HOH HOH F . 
F 4 HOH 79  379 177 HOH HOH F . 
F 4 HOH 80  380 156 HOH HOH F . 
F 4 HOH 81  381 106 HOH HOH F . 
F 4 HOH 82  382 152 HOH HOH F . 
F 4 HOH 83  383 166 HOH HOH F . 
F 4 HOH 84  384 183 HOH HOH F . 
F 4 HOH 85  385 189 HOH HOH F . 
F 4 HOH 86  386 217 HOH HOH F . 
F 4 HOH 87  387 157 HOH HOH F . 
F 4 HOH 88  388 149 HOH HOH F . 
F 4 HOH 89  389 97  HOH HOH F . 
F 4 HOH 90  390 216 HOH HOH F . 
F 4 HOH 91  391 191 HOH HOH F . 
F 4 HOH 92  392 155 HOH HOH F . 
F 4 HOH 93  393 223 HOH HOH F . 
F 4 HOH 94  394 170 HOH HOH F . 
F 4 HOH 95  395 187 HOH HOH F . 
F 4 HOH 96  396 113 HOH HOH F . 
F 4 HOH 97  397 112 HOH HOH F . 
F 4 HOH 98  398 178 HOH HOH F . 
F 4 HOH 99  399 94  HOH HOH F . 
F 4 HOH 100 400 182 HOH HOH F . 
F 4 HOH 101 401 185 HOH HOH F . 
F 4 HOH 102 402 118 HOH HOH F . 
F 4 HOH 103 403 186 HOH HOH F . 
F 4 HOH 104 404 173 HOH HOH F . 
F 4 HOH 105 405 107 HOH HOH F . 
F 4 HOH 106 406 116 HOH HOH F . 
F 4 HOH 107 407 151 HOH HOH F . 
F 4 HOH 108 408 165 HOH HOH F . 
F 4 HOH 109 409 188 HOH HOH F . 
F 4 HOH 110 410 132 HOH HOH F . 
F 4 HOH 111 411 101 HOH HOH F . 
F 4 HOH 112 412 161 HOH HOH F . 
F 4 HOH 113 413 199 HOH HOH F . 
F 4 HOH 114 414 203 HOH HOH F . 
F 4 HOH 115 415 231 HOH HOH F . 
F 4 HOH 116 416 210 HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 D DT  32  ? "C5'" ? B DT  16 "C5'" 
2  1 Y 1 D DT  32  ? "C4'" ? B DT  16 "C4'" 
3  1 Y 1 D DT  32  ? "O4'" ? B DT  16 "O4'" 
4  1 Y 1 D DT  32  ? "C3'" ? B DT  16 "C3'" 
5  1 Y 1 D DT  32  ? "O3'" ? B DT  16 "O3'" 
6  1 Y 1 D DT  32  ? "C2'" ? B DT  16 "C2'" 
7  1 Y 1 D DT  32  ? "C1'" ? B DT  16 "C1'" 
8  1 Y 1 D DT  32  ? N1    ? B DT  16 N1    
9  1 Y 1 D DT  32  ? C2    ? B DT  16 C2    
10 1 Y 1 D DT  32  ? O2    ? B DT  16 O2    
11 1 Y 1 D DT  32  ? N3    ? B DT  16 N3    
12 1 Y 1 D DT  32  ? C4    ? B DT  16 C4    
13 1 Y 1 D DT  32  ? O4    ? B DT  16 O4    
14 1 Y 1 D DT  32  ? C5    ? B DT  16 C5    
15 1 Y 1 D DT  32  ? C7    ? B DT  16 C7    
16 1 Y 1 D DT  32  ? C6    ? B DT  16 C6    
17 1 Y 1 F LYS 169 ? CG    ? C LYS 5  CG    
18 1 Y 1 F LYS 169 ? CD    ? C LYS 5  CD    
19 1 Y 1 F LYS 169 ? CE    ? C LYS 5  CE    
20 1 Y 1 F LYS 169 ? NZ    ? C LYS 5  NZ    
21 1 Y 1 F ARG 259 ? CG    ? C ARG 95 CG    
22 1 Y 1 F ARG 259 ? CD    ? C ARG 95 CD    
23 1 Y 1 F ARG 259 ? NE    ? C ARG 95 NE    
24 1 Y 1 F ARG 259 ? CZ    ? C ARG 95 CZ    
25 1 Y 1 F ARG 259 ? NH1   ? C ARG 95 NH1   
26 1 Y 1 F ARG 259 ? NH2   ? C ARG 95 NH2   
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 ? 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           ? 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           ? 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           ? 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   116.593 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9OA4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     43.134 
_cell.length_a_esd                 ? 
_cell.length_b                     60.695 
_cell.length_b_esd                 ? 
_cell.length_c                     44.802 
_cell.length_c_esd                 ? 
_cell.volume                       104883.955 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9OA4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9OA4 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.36 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          47.82 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              4.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2% PEG 3350, 100 mM Sodium Acetate, pH 4.6' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-07-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    'Vertical DCM' 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.920119 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NSLS-II BEAMLINE 17-ID-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.920119 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   17-ID-1 
_diffrn_source.pdbx_synchrotron_site       NSLS-II 
# 
_reflns.B_iso_Wilson_estimate                          20.01 
_reflns.entry_id                                       9OA4 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.42 
_reflns.d_resolution_low                               24.19 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     38841 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.26 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.66 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.04924 
_reflns.pdbx_Rpim_I_all                                0.02424 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.04254 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.42 
_reflns_shell.d_res_low                                     1.471 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.89 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3882 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               4.3 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.4867 
_reflns_shell.pdbx_Rpim_I_all                               0.2282 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.926 
_reflns_shell.pdbx_CC_star                                  0.981 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.67 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.428 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               29.39 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9OA4 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.42 
_refine.ls_d_res_low                             24.19 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     38768 
_refine.ls_number_reflns_R_free                  1985 
_refine.ls_number_reflns_R_work                  36783 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.28 
_refine.ls_percent_reflns_R_free                 5.12 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1610 
_refine.ls_R_factor_R_free                       0.1946 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1592 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 19.5153 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1418 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.42 
_refine_hist.d_res_low                        24.19 
_refine_hist.number_atoms_solvent             239 
_refine_hist.number_atoms_total               1625 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        751 
_refine_hist.pdbx_number_atoms_nucleic_acid   635 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0078  ? 1493 ? f_bond_d           ? ? ? 
'X-RAY DIFFRACTION' ? 1.0372  ? 2137 ? f_angle_d          ? ? ? 
'X-RAY DIFFRACTION' ? 0.0616  ? 228  ? f_chiral_restr     ? ? ? 
'X-RAY DIFFRACTION' ? 0.0163  ? 159  ? f_plane_restr      ? ? ? 
'X-RAY DIFFRACTION' ? 24.1832 ? 610  ? f_dihedral_angle_d ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.42 1.46  . . 140 2627 99.64 . . . . 0.2222 . . . . . . . . . . . . . . . 0.2507 
'X-RAY DIFFRACTION' 1.46 1.49  . . 134 2664 99.71 . . . . 0.1973 . . . . . . . . . . . . . . . 0.2312 
'X-RAY DIFFRACTION' 1.49 1.54  . . 151 2610 99.78 . . . . 0.1688 . . . . . . . . . . . . . . . 0.2124 
'X-RAY DIFFRACTION' 1.54 1.59  . . 131 2607 99.74 . . . . 0.1504 . . . . . . . . . . . . . . . 0.2259 
'X-RAY DIFFRACTION' 1.59 1.65  . . 152 2638 99.57 . . . . 0.1395 . . . . . . . . . . . . . . . 0.1843 
'X-RAY DIFFRACTION' 1.65 1.71  . . 137 2605 98.95 . . . . 0.1333 . . . . . . . . . . . . . . . 0.1773 
'X-RAY DIFFRACTION' 1.71 1.79  . . 154 2615 98.68 . . . . 0.1330 . . . . . . . . . . . . . . . 0.1724 
'X-RAY DIFFRACTION' 1.79 1.88  . . 131 2593 99.13 . . . . 0.1311 . . . . . . . . . . . . . . . 0.1657 
'X-RAY DIFFRACTION' 1.88 2.00  . . 146 2622 99.86 . . . . 0.1468 . . . . . . . . . . . . . . . 0.1815 
'X-RAY DIFFRACTION' 2.00 2.16  . . 147 2650 99.57 . . . . 0.1505 . . . . . . . . . . . . . . . 0.2179 
'X-RAY DIFFRACTION' 2.16 2.37  . . 137 2635 99.50 . . . . 0.1486 . . . . . . . . . . . . . . . 0.1914 
'X-RAY DIFFRACTION' 2.37 2.72  . . 135 2651 99.75 . . . . 0.1583 . . . . . . . . . . . . . . . 0.2034 
'X-RAY DIFFRACTION' 2.72 3.42  . . 139 2636 98.82 . . . . 0.1738 . . . . . . . . . . . . . . . 0.1932 
'X-RAY DIFFRACTION' 3.42 24.19 . . 151 2630 97.34 . . . . 0.1650 . . . . . . . . . . . . . . . 0.1920 
# 
_struct.entry_id                     9OA4 
_struct.title                        
;Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGGAAGTGGG-3') d(5'-TCCCACTTTCGCTTAT-3') with a GT mismatch
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9OA4 
_struct_keywords.text            
'transcription factor, protein-DNA complex, ETS family, ETS, PU.1, TRANSCRIPTION-DNA complex, DNA mismatch, TRANSCRIPTION' 
_struct_keywords.pdbx_keywords   TRANSCRIPTION/DNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9OA4       9OA4   ? 1 ? 1   
2 PDB 9OA4       9OA4   ? 2 ? 1   
3 UNP SPI1_HUMAN P17947 ? 3 
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
165 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9OA4 C 1 ? 16  ? 9OA4   1   ? 16  ? 1   16  
2 2 9OA4 D 1 ? 16  ? 9OA4   17  ? 32  ? 17  32  
3 3 9OA4 F 1 ? 106 ? P17947 165 ? 270 ? 165 270 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3290  ? 
1 MORE         -21   ? 
1 'SSA (A^2)'  10130 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ARG C 7  ? GLY C 19 ? ARG F 171 GLY F 183 1 ? 13 
HELX_P HELX_P2 AA2 LYS C 30 ? LYS C 32 ? LYS F 194 LYS F 196 5 ? 3  
HELX_P HELX_P3 AA3 HIS C 41 ? GLY C 54 ? HIS F 205 GLY F 218 1 ? 14 
HELX_P HELX_P4 AA4 THR C 60 ? TYR C 71 ? THR F 224 TYR F 235 1 ? 12 
HELX_P HELX_P5 AA5 SER C 89 ? ARG C 95 ? SER F 253 ARG F 259 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? A DT 3  N3 ? ? ? 1_555 B DA 15 N1 ? ? C DT 3  D DA 31 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog2  hydrog ? ? A DT 3  O4 ? ? ? 1_555 B DA 15 N6 ? ? C DT 3  D DA 31 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog3  hydrog ? ? A DA 4  N1 ? ? ? 1_555 B DT 14 N3 ? ? C DA 4  D DT 30 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog4  hydrog ? ? A DA 4  N6 ? ? ? 1_555 B DT 14 O4 ? ? C DA 4  D DT 30 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog5  hydrog ? ? A DA 5  N1 ? ? ? 1_555 B DT 13 N3 ? ? C DA 5  D DT 29 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog6  hydrog ? ? A DA 5  N6 ? ? ? 1_555 B DT 13 O4 ? ? C DA 5  D DT 29 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog7  hydrog ? ? A DG 6  N1 ? ? ? 1_555 B DC 12 N3 ? ? C DG 6  D DC 28 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog8  hydrog ? ? A DG 6  N2 ? ? ? 1_555 B DC 12 O2 ? ? C DG 6  D DC 28 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog9  hydrog ? ? A DG 6  O6 ? ? ? 1_555 B DC 12 N4 ? ? C DG 6  D DC 28 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog10 hydrog ? ? A DC 7  N3 ? ? ? 1_555 B DG 11 N1 ? ? C DC 7  D DG 27 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog11 hydrog ? ? A DC 7  N4 ? ? ? 1_555 B DG 11 O6 ? ? C DC 7  D DG 27 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog12 hydrog ? ? A DC 7  O2 ? ? ? 1_555 B DG 11 N2 ? ? C DC 7  D DG 27 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog13 hydrog ? ? A DG 8  N1 ? ? ? 1_555 B DC 10 N3 ? ? C DG 8  D DC 26 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog14 hydrog ? ? A DG 8  N2 ? ? ? 1_555 B DC 10 O2 ? ? C DG 8  D DC 26 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog15 hydrog ? ? A DG 8  O6 ? ? ? 1_555 B DC 10 N4 ? ? C DG 8  D DC 26 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog16 hydrog ? ? A DG 9  N1 ? ? ? 1_555 B DT 9  O2 ? ? C DG 9  D DT 25 1_555 ? ? ? ? ? ? TYPE_28_PAIR ? ? ? 
hydrog17 hydrog ? ? A DG 9  O6 ? ? ? 1_555 B DT 9  N3 ? ? C DG 9  D DT 25 1_555 ? ? ? ? ? ? TYPE_28_PAIR ? ? ? 
hydrog18 hydrog ? ? A DA 10 N1 ? ? ? 1_555 B DT 8  N3 ? ? C DA 10 D DT 24 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog19 hydrog ? ? A DA 10 N6 ? ? ? 1_555 B DT 8  O4 ? ? C DA 10 D DT 24 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog20 hydrog ? ? A DA 11 N1 ? ? ? 1_555 B DT 7  N3 ? ? C DA 11 D DT 23 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog21 hydrog ? ? A DA 11 N6 ? ? ? 1_555 B DT 7  O4 ? ? C DA 11 D DT 23 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog22 hydrog ? ? A DG 12 N1 ? ? ? 1_555 B DC 6  N3 ? ? C DG 12 D DC 22 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog23 hydrog ? ? A DG 12 N2 ? ? ? 1_555 B DC 6  O2 ? ? C DG 12 D DC 22 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog24 hydrog ? ? A DG 12 O6 ? ? ? 1_555 B DC 6  N4 ? ? C DG 12 D DC 22 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog25 hydrog ? ? A DT 13 N3 ? ? ? 1_555 B DA 5  N1 ? ? C DT 13 D DA 21 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog26 hydrog ? ? A DT 13 O4 ? ? ? 1_555 B DA 5  N6 ? ? C DT 13 D DA 21 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog27 hydrog ? ? A DG 14 O6 ? ? ? 1_555 B DC 4  N4 ? ? C DG 14 D DC 20 1_555 ? ? ? ? ? ? 'DG-DC PAIR' ? ? ? 
hydrog28 hydrog ? ? A DG 15 N1 ? ? ? 1_555 B DC 3  N3 ? ? C DG 15 D DC 19 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog29 hydrog ? ? A DG 15 N2 ? ? ? 1_555 B DC 3  O2 ? ? C DG 15 D DC 19 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog30 hydrog ? ? A DG 15 O6 ? ? ? 1_555 B DC 3  N4 ? ? C DG 15 D DC 19 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog31 hydrog ? ? A DG 16 N1 ? ? ? 1_555 B DC 2  N3 ? ? C DG 16 D DC 18 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog32 hydrog ? ? A DG 16 N2 ? ? ? 1_555 B DC 2  O2 ? ? C DG 16 D DC 18 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog33 hydrog ? ? A DG 16 O6 ? ? ? 1_555 B DC 2  N4 ? ? C DG 16 D DC 18 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   4 
_struct_sheet.details          ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE C 25 ? ASP C 29 ? ILE F 189 ASP F 193 
AA1 2 THR C 34 ? PHE C 37 ? THR F 198 PHE F 201 
AA1 3 THR C 85 ? PHE C 88 ? THR F 249 PHE F 252 
AA1 4 VAL C 77 ? LYS C 79 ? VAL F 241 LYS F 243 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL C 28 ? N VAL F 192 O THR C 34 ? O THR F 198 
AA1 2 3 N PHE C 35 ? N PHE F 199 O TYR C 86 ? O TYR F 250 
AA1 3 4 O GLN C 87 ? O GLN F 251 N LYS C 78 ? N LYS F 242 
# 
_pdbx_entry_details.entry_id                   9OA4 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OP2 D DC  28  ? ? O D HOH 101 ? ? 2.07 
2 1 O   F ARG 259 ? ? O F HOH 301 ? ? 2.08 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 "O4'" C DG 8  ? ? "C1'" C DG 8  ? ? N9 C DG 8  ? ? 110.84 108.30 2.54 0.30 N 
2 1 "O4'" C DG 15 ? ? "C1'" C DG 15 ? ? N9 C DG 15 ? ? 110.30 108.30 2.00 0.30 N 
3 1 "O4'" D DC 18 ? ? "C1'" D DC 18 ? ? N1 D DC 18 ? ? 110.60 108.30 2.30 0.30 N 
4 1 "O4'" D DA 21 ? ? "C1'" D DA 21 ? ? N9 D DA 21 ? ? 110.17 108.30 1.87 0.30 N 
5 1 "O4'" D DC 22 ? ? "C1'" D DC 22 ? ? N1 D DC 22 ? ? 110.42 108.30 2.12 0.30 N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    LYS 
_pdbx_validate_torsion.auth_asym_id    F 
_pdbx_validate_torsion.auth_seq_id     245 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -80.44 
_pdbx_validate_torsion.psi             49.34 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    F 
_pdbx_validate_planes.auth_seq_id     230 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.085 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 F GLY 165 ? C GLY 1   
2  1 Y 1 F SER 166 ? C SER 2   
3  1 Y 1 F LYS 167 ? C LYS 3   
4  1 Y 1 F LYS 168 ? C LYS 4   
5  1 Y 1 F GLY 260 ? C GLY 96  
6  1 Y 1 F GLY 261 ? C GLY 97  
7  1 Y 1 F LEU 262 ? C LEU 98  
8  1 Y 1 F ALA 263 ? C ALA 99  
9  1 Y 1 F GLU 264 ? C GLU 100 
10 1 Y 1 F ARG 265 ? C ARG 101 
11 1 Y 1 F ARG 266 ? C ARG 102 
12 1 Y 1 F HIS 267 ? C HIS 103 
13 1 Y 1 F PRO 268 ? C PRO 104 
14 1 Y 1 F PRO 269 ? C PRO 105 
15 1 Y 1 F HIS 270 ? C HIS 106 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
DA  OP3    O N N 74  
DA  P      P N N 75  
DA  OP1    O N N 76  
DA  OP2    O N N 77  
DA  "O5'"  O N N 78  
DA  "C5'"  C N N 79  
DA  "C4'"  C N R 80  
DA  "O4'"  O N N 81  
DA  "C3'"  C N S 82  
DA  "O3'"  O N N 83  
DA  "C2'"  C N N 84  
DA  "C1'"  C N R 85  
DA  N9     N Y N 86  
DA  C8     C Y N 87  
DA  N7     N Y N 88  
DA  C5     C Y N 89  
DA  C6     C Y N 90  
DA  N6     N N N 91  
DA  N1     N Y N 92  
DA  C2     C Y N 93  
DA  N3     N Y N 94  
DA  C4     C Y N 95  
DA  HOP3   H N N 96  
DA  HOP2   H N N 97  
DA  "H5'"  H N N 98  
DA  "H5''" H N N 99  
DA  "H4'"  H N N 100 
DA  "H3'"  H N N 101 
DA  "HO3'" H N N 102 
DA  "H2'"  H N N 103 
DA  "H2''" H N N 104 
DA  "H1'"  H N N 105 
DA  H8     H N N 106 
DA  H61    H N N 107 
DA  H62    H N N 108 
DA  H2     H N N 109 
DC  OP3    O N N 110 
DC  P      P N N 111 
DC  OP1    O N N 112 
DC  OP2    O N N 113 
DC  "O5'"  O N N 114 
DC  "C5'"  C N N 115 
DC  "C4'"  C N R 116 
DC  "O4'"  O N N 117 
DC  "C3'"  C N S 118 
DC  "O3'"  O N N 119 
DC  "C2'"  C N N 120 
DC  "C1'"  C N R 121 
DC  N1     N N N 122 
DC  C2     C N N 123 
DC  O2     O N N 124 
DC  N3     N N N 125 
DC  C4     C N N 126 
DC  N4     N N N 127 
DC  C5     C N N 128 
DC  C6     C N N 129 
DC  HOP3   H N N 130 
DC  HOP2   H N N 131 
DC  "H5'"  H N N 132 
DC  "H5''" H N N 133 
DC  "H4'"  H N N 134 
DC  "H3'"  H N N 135 
DC  "HO3'" H N N 136 
DC  "H2'"  H N N 137 
DC  "H2''" H N N 138 
DC  "H1'"  H N N 139 
DC  H41    H N N 140 
DC  H42    H N N 141 
DC  H5     H N N 142 
DC  H6     H N N 143 
DG  OP3    O N N 144 
DG  P      P N N 145 
DG  OP1    O N N 146 
DG  OP2    O N N 147 
DG  "O5'"  O N N 148 
DG  "C5'"  C N N 149 
DG  "C4'"  C N R 150 
DG  "O4'"  O N N 151 
DG  "C3'"  C N S 152 
DG  "O3'"  O N N 153 
DG  "C2'"  C N N 154 
DG  "C1'"  C N R 155 
DG  N9     N Y N 156 
DG  C8     C Y N 157 
DG  N7     N Y N 158 
DG  C5     C Y N 159 
DG  C6     C N N 160 
DG  O6     O N N 161 
DG  N1     N N N 162 
DG  C2     C N N 163 
DG  N2     N N N 164 
DG  N3     N N N 165 
DG  C4     C Y N 166 
DG  HOP3   H N N 167 
DG  HOP2   H N N 168 
DG  "H5'"  H N N 169 
DG  "H5''" H N N 170 
DG  "H4'"  H N N 171 
DG  "H3'"  H N N 172 
DG  "HO3'" H N N 173 
DG  "H2'"  H N N 174 
DG  "H2''" H N N 175 
DG  "H1'"  H N N 176 
DG  H8     H N N 177 
DG  H1     H N N 178 
DG  H21    H N N 179 
DG  H22    H N N 180 
DT  OP3    O N N 181 
DT  P      P N N 182 
DT  OP1    O N N 183 
DT  OP2    O N N 184 
DT  "O5'"  O N N 185 
DT  "C5'"  C N N 186 
DT  "C4'"  C N R 187 
DT  "O4'"  O N N 188 
DT  "C3'"  C N S 189 
DT  "O3'"  O N N 190 
DT  "C2'"  C N N 191 
DT  "C1'"  C N R 192 
DT  N1     N N N 193 
DT  C2     C N N 194 
DT  O2     O N N 195 
DT  N3     N N N 196 
DT  C4     C N N 197 
DT  O4     O N N 198 
DT  C5     C N N 199 
DT  C7     C N N 200 
DT  C6     C N N 201 
DT  HOP3   H N N 202 
DT  HOP2   H N N 203 
DT  "H5'"  H N N 204 
DT  "H5''" H N N 205 
DT  "H4'"  H N N 206 
DT  "H3'"  H N N 207 
DT  "HO3'" H N N 208 
DT  "H2'"  H N N 209 
DT  "H2''" H N N 210 
DT  "H1'"  H N N 211 
DT  H3     H N N 212 
DT  H71    H N N 213 
DT  H72    H N N 214 
DT  H73    H N N 215 
DT  H6     H N N 216 
GLN N      N N N 217 
GLN CA     C N S 218 
GLN C      C N N 219 
GLN O      O N N 220 
GLN CB     C N N 221 
GLN CG     C N N 222 
GLN CD     C N N 223 
GLN OE1    O N N 224 
GLN NE2    N N N 225 
GLN OXT    O N N 226 
GLN H      H N N 227 
GLN H2     H N N 228 
GLN HA     H N N 229 
GLN HB2    H N N 230 
GLN HB3    H N N 231 
GLN HG2    H N N 232 
GLN HG3    H N N 233 
GLN HE21   H N N 234 
GLN HE22   H N N 235 
GLN HXT    H N N 236 
GLU N      N N N 237 
GLU CA     C N S 238 
GLU C      C N N 239 
GLU O      O N N 240 
GLU CB     C N N 241 
GLU CG     C N N 242 
GLU CD     C N N 243 
GLU OE1    O N N 244 
GLU OE2    O N N 245 
GLU OXT    O N N 246 
GLU H      H N N 247 
GLU H2     H N N 248 
GLU HA     H N N 249 
GLU HB2    H N N 250 
GLU HB3    H N N 251 
GLU HG2    H N N 252 
GLU HG3    H N N 253 
GLU HE2    H N N 254 
GLU HXT    H N N 255 
GLY N      N N N 256 
GLY CA     C N N 257 
GLY C      C N N 258 
GLY O      O N N 259 
GLY OXT    O N N 260 
GLY H      H N N 261 
GLY H2     H N N 262 
GLY HA2    H N N 263 
GLY HA3    H N N 264 
GLY HXT    H N N 265 
HIS N      N N N 266 
HIS CA     C N S 267 
HIS C      C N N 268 
HIS O      O N N 269 
HIS CB     C N N 270 
HIS CG     C Y N 271 
HIS ND1    N Y N 272 
HIS CD2    C Y N 273 
HIS CE1    C Y N 274 
HIS NE2    N Y N 275 
HIS OXT    O N N 276 
HIS H      H N N 277 
HIS H2     H N N 278 
HIS HA     H N N 279 
HIS HB2    H N N 280 
HIS HB3    H N N 281 
HIS HD1    H N N 282 
HIS HD2    H N N 283 
HIS HE1    H N N 284 
HIS HE2    H N N 285 
HIS HXT    H N N 286 
HOH O      O N N 287 
HOH H1     H N N 288 
HOH H2     H N N 289 
ILE N      N N N 290 
ILE CA     C N S 291 
ILE C      C N N 292 
ILE O      O N N 293 
ILE CB     C N S 294 
ILE CG1    C N N 295 
ILE CG2    C N N 296 
ILE CD1    C N N 297 
ILE OXT    O N N 298 
ILE H      H N N 299 
ILE H2     H N N 300 
ILE HA     H N N 301 
ILE HB     H N N 302 
ILE HG12   H N N 303 
ILE HG13   H N N 304 
ILE HG21   H N N 305 
ILE HG22   H N N 306 
ILE HG23   H N N 307 
ILE HD11   H N N 308 
ILE HD12   H N N 309 
ILE HD13   H N N 310 
ILE HXT    H N N 311 
LEU N      N N N 312 
LEU CA     C N S 313 
LEU C      C N N 314 
LEU O      O N N 315 
LEU CB     C N N 316 
LEU CG     C N N 317 
LEU CD1    C N N 318 
LEU CD2    C N N 319 
LEU OXT    O N N 320 
LEU H      H N N 321 
LEU H2     H N N 322 
LEU HA     H N N 323 
LEU HB2    H N N 324 
LEU HB3    H N N 325 
LEU HG     H N N 326 
LEU HD11   H N N 327 
LEU HD12   H N N 328 
LEU HD13   H N N 329 
LEU HD21   H N N 330 
LEU HD22   H N N 331 
LEU HD23   H N N 332 
LEU HXT    H N N 333 
LYS N      N N N 334 
LYS CA     C N S 335 
LYS C      C N N 336 
LYS O      O N N 337 
LYS CB     C N N 338 
LYS CG     C N N 339 
LYS CD     C N N 340 
LYS CE     C N N 341 
LYS NZ     N N N 342 
LYS OXT    O N N 343 
LYS H      H N N 344 
LYS H2     H N N 345 
LYS HA     H N N 346 
LYS HB2    H N N 347 
LYS HB3    H N N 348 
LYS HG2    H N N 349 
LYS HG3    H N N 350 
LYS HD2    H N N 351 
LYS HD3    H N N 352 
LYS HE2    H N N 353 
LYS HE3    H N N 354 
LYS HZ1    H N N 355 
LYS HZ2    H N N 356 
LYS HZ3    H N N 357 
LYS HXT    H N N 358 
MET N      N N N 359 
MET CA     C N S 360 
MET C      C N N 361 
MET O      O N N 362 
MET CB     C N N 363 
MET CG     C N N 364 
MET SD     S N N 365 
MET CE     C N N 366 
MET OXT    O N N 367 
MET H      H N N 368 
MET H2     H N N 369 
MET HA     H N N 370 
MET HB2    H N N 371 
MET HB3    H N N 372 
MET HG2    H N N 373 
MET HG3    H N N 374 
MET HE1    H N N 375 
MET HE2    H N N 376 
MET HE3    H N N 377 
MET HXT    H N N 378 
PHE N      N N N 379 
PHE CA     C N S 380 
PHE C      C N N 381 
PHE O      O N N 382 
PHE CB     C N N 383 
PHE CG     C Y N 384 
PHE CD1    C Y N 385 
PHE CD2    C Y N 386 
PHE CE1    C Y N 387 
PHE CE2    C Y N 388 
PHE CZ     C Y N 389 
PHE OXT    O N N 390 
PHE H      H N N 391 
PHE H2     H N N 392 
PHE HA     H N N 393 
PHE HB2    H N N 394 
PHE HB3    H N N 395 
PHE HD1    H N N 396 
PHE HD2    H N N 397 
PHE HE1    H N N 398 
PHE HE2    H N N 399 
PHE HZ     H N N 400 
PHE HXT    H N N 401 
PRO N      N N N 402 
PRO CA     C N S 403 
PRO C      C N N 404 
PRO O      O N N 405 
PRO CB     C N N 406 
PRO CG     C N N 407 
PRO CD     C N N 408 
PRO OXT    O N N 409 
PRO H      H N N 410 
PRO HA     H N N 411 
PRO HB2    H N N 412 
PRO HB3    H N N 413 
PRO HG2    H N N 414 
PRO HG3    H N N 415 
PRO HD2    H N N 416 
PRO HD3    H N N 417 
PRO HXT    H N N 418 
SER N      N N N 419 
SER CA     C N S 420 
SER C      C N N 421 
SER O      O N N 422 
SER CB     C N N 423 
SER OG     O N N 424 
SER OXT    O N N 425 
SER H      H N N 426 
SER H2     H N N 427 
SER HA     H N N 428 
SER HB2    H N N 429 
SER HB3    H N N 430 
SER HG     H N N 431 
SER HXT    H N N 432 
THR N      N N N 433 
THR CA     C N S 434 
THR C      C N N 435 
THR O      O N N 436 
THR CB     C N R 437 
THR OG1    O N N 438 
THR CG2    C N N 439 
THR OXT    O N N 440 
THR H      H N N 441 
THR H2     H N N 442 
THR HA     H N N 443 
THR HB     H N N 444 
THR HG1    H N N 445 
THR HG21   H N N 446 
THR HG22   H N N 447 
THR HG23   H N N 448 
THR HXT    H N N 449 
TRP N      N N N 450 
TRP CA     C N S 451 
TRP C      C N N 452 
TRP O      O N N 453 
TRP CB     C N N 454 
TRP CG     C Y N 455 
TRP CD1    C Y N 456 
TRP CD2    C Y N 457 
TRP NE1    N Y N 458 
TRP CE2    C Y N 459 
TRP CE3    C Y N 460 
TRP CZ2    C Y N 461 
TRP CZ3    C Y N 462 
TRP CH2    C Y N 463 
TRP OXT    O N N 464 
TRP H      H N N 465 
TRP H2     H N N 466 
TRP HA     H N N 467 
TRP HB2    H N N 468 
TRP HB3    H N N 469 
TRP HD1    H N N 470 
TRP HE1    H N N 471 
TRP HE3    H N N 472 
TRP HZ2    H N N 473 
TRP HZ3    H N N 474 
TRP HH2    H N N 475 
TRP HXT    H N N 476 
TYR N      N N N 477 
TYR CA     C N S 478 
TYR C      C N N 479 
TYR O      O N N 480 
TYR CB     C N N 481 
TYR CG     C Y N 482 
TYR CD1    C Y N 483 
TYR CD2    C Y N 484 
TYR CE1    C Y N 485 
TYR CE2    C Y N 486 
TYR CZ     C Y N 487 
TYR OH     O N N 488 
TYR OXT    O N N 489 
TYR H      H N N 490 
TYR H2     H N N 491 
TYR HA     H N N 492 
TYR HB2    H N N 493 
TYR HB3    H N N 494 
TYR HD1    H N N 495 
TYR HD2    H N N 496 
TYR HE1    H N N 497 
TYR HE2    H N N 498 
TYR HH     H N N 499 
TYR HXT    H N N 500 
VAL N      N N N 501 
VAL CA     C N S 502 
VAL C      C N N 503 
VAL O      O N N 504 
VAL CB     C N N 505 
VAL CG1    C N N 506 
VAL CG2    C N N 507 
VAL OXT    O N N 508 
VAL H      H N N 509 
VAL H2     H N N 510 
VAL HA     H N N 511 
VAL HB     H N N 512 
VAL HG11   H N N 513 
VAL HG12   H N N 514 
VAL HG13   H N N 515 
VAL HG21   H N N 516 
VAL HG22   H N N 517 
VAL HG23   H N N 518 
VAL HXT    H N N 519 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
DA  OP3   P      sing N N 70  
DA  OP3   HOP3   sing N N 71  
DA  P     OP1    doub N N 72  
DA  P     OP2    sing N N 73  
DA  P     "O5'"  sing N N 74  
DA  OP2   HOP2   sing N N 75  
DA  "O5'" "C5'"  sing N N 76  
DA  "C5'" "C4'"  sing N N 77  
DA  "C5'" "H5'"  sing N N 78  
DA  "C5'" "H5''" sing N N 79  
DA  "C4'" "O4'"  sing N N 80  
DA  "C4'" "C3'"  sing N N 81  
DA  "C4'" "H4'"  sing N N 82  
DA  "O4'" "C1'"  sing N N 83  
DA  "C3'" "O3'"  sing N N 84  
DA  "C3'" "C2'"  sing N N 85  
DA  "C3'" "H3'"  sing N N 86  
DA  "O3'" "HO3'" sing N N 87  
DA  "C2'" "C1'"  sing N N 88  
DA  "C2'" "H2'"  sing N N 89  
DA  "C2'" "H2''" sing N N 90  
DA  "C1'" N9     sing N N 91  
DA  "C1'" "H1'"  sing N N 92  
DA  N9    C8     sing Y N 93  
DA  N9    C4     sing Y N 94  
DA  C8    N7     doub Y N 95  
DA  C8    H8     sing N N 96  
DA  N7    C5     sing Y N 97  
DA  C5    C6     sing Y N 98  
DA  C5    C4     doub Y N 99  
DA  C6    N6     sing N N 100 
DA  C6    N1     doub Y N 101 
DA  N6    H61    sing N N 102 
DA  N6    H62    sing N N 103 
DA  N1    C2     sing Y N 104 
DA  C2    N3     doub Y N 105 
DA  C2    H2     sing N N 106 
DA  N3    C4     sing Y N 107 
DC  OP3   P      sing N N 108 
DC  OP3   HOP3   sing N N 109 
DC  P     OP1    doub N N 110 
DC  P     OP2    sing N N 111 
DC  P     "O5'"  sing N N 112 
DC  OP2   HOP2   sing N N 113 
DC  "O5'" "C5'"  sing N N 114 
DC  "C5'" "C4'"  sing N N 115 
DC  "C5'" "H5'"  sing N N 116 
DC  "C5'" "H5''" sing N N 117 
DC  "C4'" "O4'"  sing N N 118 
DC  "C4'" "C3'"  sing N N 119 
DC  "C4'" "H4'"  sing N N 120 
DC  "O4'" "C1'"  sing N N 121 
DC  "C3'" "O3'"  sing N N 122 
DC  "C3'" "C2'"  sing N N 123 
DC  "C3'" "H3'"  sing N N 124 
DC  "O3'" "HO3'" sing N N 125 
DC  "C2'" "C1'"  sing N N 126 
DC  "C2'" "H2'"  sing N N 127 
DC  "C2'" "H2''" sing N N 128 
DC  "C1'" N1     sing N N 129 
DC  "C1'" "H1'"  sing N N 130 
DC  N1    C2     sing N N 131 
DC  N1    C6     sing N N 132 
DC  C2    O2     doub N N 133 
DC  C2    N3     sing N N 134 
DC  N3    C4     doub N N 135 
DC  C4    N4     sing N N 136 
DC  C4    C5     sing N N 137 
DC  N4    H41    sing N N 138 
DC  N4    H42    sing N N 139 
DC  C5    C6     doub N N 140 
DC  C5    H5     sing N N 141 
DC  C6    H6     sing N N 142 
DG  OP3   P      sing N N 143 
DG  OP3   HOP3   sing N N 144 
DG  P     OP1    doub N N 145 
DG  P     OP2    sing N N 146 
DG  P     "O5'"  sing N N 147 
DG  OP2   HOP2   sing N N 148 
DG  "O5'" "C5'"  sing N N 149 
DG  "C5'" "C4'"  sing N N 150 
DG  "C5'" "H5'"  sing N N 151 
DG  "C5'" "H5''" sing N N 152 
DG  "C4'" "O4'"  sing N N 153 
DG  "C4'" "C3'"  sing N N 154 
DG  "C4'" "H4'"  sing N N 155 
DG  "O4'" "C1'"  sing N N 156 
DG  "C3'" "O3'"  sing N N 157 
DG  "C3'" "C2'"  sing N N 158 
DG  "C3'" "H3'"  sing N N 159 
DG  "O3'" "HO3'" sing N N 160 
DG  "C2'" "C1'"  sing N N 161 
DG  "C2'" "H2'"  sing N N 162 
DG  "C2'" "H2''" sing N N 163 
DG  "C1'" N9     sing N N 164 
DG  "C1'" "H1'"  sing N N 165 
DG  N9    C8     sing Y N 166 
DG  N9    C4     sing Y N 167 
DG  C8    N7     doub Y N 168 
DG  C8    H8     sing N N 169 
DG  N7    C5     sing Y N 170 
DG  C5    C6     sing N N 171 
DG  C5    C4     doub Y N 172 
DG  C6    O6     doub N N 173 
DG  C6    N1     sing N N 174 
DG  N1    C2     sing N N 175 
DG  N1    H1     sing N N 176 
DG  C2    N2     sing N N 177 
DG  C2    N3     doub N N 178 
DG  N2    H21    sing N N 179 
DG  N2    H22    sing N N 180 
DG  N3    C4     sing N N 181 
DT  OP3   P      sing N N 182 
DT  OP3   HOP3   sing N N 183 
DT  P     OP1    doub N N 184 
DT  P     OP2    sing N N 185 
DT  P     "O5'"  sing N N 186 
DT  OP2   HOP2   sing N N 187 
DT  "O5'" "C5'"  sing N N 188 
DT  "C5'" "C4'"  sing N N 189 
DT  "C5'" "H5'"  sing N N 190 
DT  "C5'" "H5''" sing N N 191 
DT  "C4'" "O4'"  sing N N 192 
DT  "C4'" "C3'"  sing N N 193 
DT  "C4'" "H4'"  sing N N 194 
DT  "O4'" "C1'"  sing N N 195 
DT  "C3'" "O3'"  sing N N 196 
DT  "C3'" "C2'"  sing N N 197 
DT  "C3'" "H3'"  sing N N 198 
DT  "O3'" "HO3'" sing N N 199 
DT  "C2'" "C1'"  sing N N 200 
DT  "C2'" "H2'"  sing N N 201 
DT  "C2'" "H2''" sing N N 202 
DT  "C1'" N1     sing N N 203 
DT  "C1'" "H1'"  sing N N 204 
DT  N1    C2     sing N N 205 
DT  N1    C6     sing N N 206 
DT  C2    O2     doub N N 207 
DT  C2    N3     sing N N 208 
DT  N3    C4     sing N N 209 
DT  N3    H3     sing N N 210 
DT  C4    O4     doub N N 211 
DT  C4    C5     sing N N 212 
DT  C5    C7     sing N N 213 
DT  C5    C6     doub N N 214 
DT  C7    H71    sing N N 215 
DT  C7    H72    sing N N 216 
DT  C7    H73    sing N N 217 
DT  C6    H6     sing N N 218 
GLN N     CA     sing N N 219 
GLN N     H      sing N N 220 
GLN N     H2     sing N N 221 
GLN CA    C      sing N N 222 
GLN CA    CB     sing N N 223 
GLN CA    HA     sing N N 224 
GLN C     O      doub N N 225 
GLN C     OXT    sing N N 226 
GLN CB    CG     sing N N 227 
GLN CB    HB2    sing N N 228 
GLN CB    HB3    sing N N 229 
GLN CG    CD     sing N N 230 
GLN CG    HG2    sing N N 231 
GLN CG    HG3    sing N N 232 
GLN CD    OE1    doub N N 233 
GLN CD    NE2    sing N N 234 
GLN NE2   HE21   sing N N 235 
GLN NE2   HE22   sing N N 236 
GLN OXT   HXT    sing N N 237 
GLU N     CA     sing N N 238 
GLU N     H      sing N N 239 
GLU N     H2     sing N N 240 
GLU CA    C      sing N N 241 
GLU CA    CB     sing N N 242 
GLU CA    HA     sing N N 243 
GLU C     O      doub N N 244 
GLU C     OXT    sing N N 245 
GLU CB    CG     sing N N 246 
GLU CB    HB2    sing N N 247 
GLU CB    HB3    sing N N 248 
GLU CG    CD     sing N N 249 
GLU CG    HG2    sing N N 250 
GLU CG    HG3    sing N N 251 
GLU CD    OE1    doub N N 252 
GLU CD    OE2    sing N N 253 
GLU OE2   HE2    sing N N 254 
GLU OXT   HXT    sing N N 255 
GLY N     CA     sing N N 256 
GLY N     H      sing N N 257 
GLY N     H2     sing N N 258 
GLY CA    C      sing N N 259 
GLY CA    HA2    sing N N 260 
GLY CA    HA3    sing N N 261 
GLY C     O      doub N N 262 
GLY C     OXT    sing N N 263 
GLY OXT   HXT    sing N N 264 
HIS N     CA     sing N N 265 
HIS N     H      sing N N 266 
HIS N     H2     sing N N 267 
HIS CA    C      sing N N 268 
HIS CA    CB     sing N N 269 
HIS CA    HA     sing N N 270 
HIS C     O      doub N N 271 
HIS C     OXT    sing N N 272 
HIS CB    CG     sing N N 273 
HIS CB    HB2    sing N N 274 
HIS CB    HB3    sing N N 275 
HIS CG    ND1    sing Y N 276 
HIS CG    CD2    doub Y N 277 
HIS ND1   CE1    doub Y N 278 
HIS ND1   HD1    sing N N 279 
HIS CD2   NE2    sing Y N 280 
HIS CD2   HD2    sing N N 281 
HIS CE1   NE2    sing Y N 282 
HIS CE1   HE1    sing N N 283 
HIS NE2   HE2    sing N N 284 
HIS OXT   HXT    sing N N 285 
HOH O     H1     sing N N 286 
HOH O     H2     sing N N 287 
ILE N     CA     sing N N 288 
ILE N     H      sing N N 289 
ILE N     H2     sing N N 290 
ILE CA    C      sing N N 291 
ILE CA    CB     sing N N 292 
ILE CA    HA     sing N N 293 
ILE C     O      doub N N 294 
ILE C     OXT    sing N N 295 
ILE CB    CG1    sing N N 296 
ILE CB    CG2    sing N N 297 
ILE CB    HB     sing N N 298 
ILE CG1   CD1    sing N N 299 
ILE CG1   HG12   sing N N 300 
ILE CG1   HG13   sing N N 301 
ILE CG2   HG21   sing N N 302 
ILE CG2   HG22   sing N N 303 
ILE CG2   HG23   sing N N 304 
ILE CD1   HD11   sing N N 305 
ILE CD1   HD12   sing N N 306 
ILE CD1   HD13   sing N N 307 
ILE OXT   HXT    sing N N 308 
LEU N     CA     sing N N 309 
LEU N     H      sing N N 310 
LEU N     H2     sing N N 311 
LEU CA    C      sing N N 312 
LEU CA    CB     sing N N 313 
LEU CA    HA     sing N N 314 
LEU C     O      doub N N 315 
LEU C     OXT    sing N N 316 
LEU CB    CG     sing N N 317 
LEU CB    HB2    sing N N 318 
LEU CB    HB3    sing N N 319 
LEU CG    CD1    sing N N 320 
LEU CG    CD2    sing N N 321 
LEU CG    HG     sing N N 322 
LEU CD1   HD11   sing N N 323 
LEU CD1   HD12   sing N N 324 
LEU CD1   HD13   sing N N 325 
LEU CD2   HD21   sing N N 326 
LEU CD2   HD22   sing N N 327 
LEU CD2   HD23   sing N N 328 
LEU OXT   HXT    sing N N 329 
LYS N     CA     sing N N 330 
LYS N     H      sing N N 331 
LYS N     H2     sing N N 332 
LYS CA    C      sing N N 333 
LYS CA    CB     sing N N 334 
LYS CA    HA     sing N N 335 
LYS C     O      doub N N 336 
LYS C     OXT    sing N N 337 
LYS CB    CG     sing N N 338 
LYS CB    HB2    sing N N 339 
LYS CB    HB3    sing N N 340 
LYS CG    CD     sing N N 341 
LYS CG    HG2    sing N N 342 
LYS CG    HG3    sing N N 343 
LYS CD    CE     sing N N 344 
LYS CD    HD2    sing N N 345 
LYS CD    HD3    sing N N 346 
LYS CE    NZ     sing N N 347 
LYS CE    HE2    sing N N 348 
LYS CE    HE3    sing N N 349 
LYS NZ    HZ1    sing N N 350 
LYS NZ    HZ2    sing N N 351 
LYS NZ    HZ3    sing N N 352 
LYS OXT   HXT    sing N N 353 
MET N     CA     sing N N 354 
MET N     H      sing N N 355 
MET N     H2     sing N N 356 
MET CA    C      sing N N 357 
MET CA    CB     sing N N 358 
MET CA    HA     sing N N 359 
MET C     O      doub N N 360 
MET C     OXT    sing N N 361 
MET CB    CG     sing N N 362 
MET CB    HB2    sing N N 363 
MET CB    HB3    sing N N 364 
MET CG    SD     sing N N 365 
MET CG    HG2    sing N N 366 
MET CG    HG3    sing N N 367 
MET SD    CE     sing N N 368 
MET CE    HE1    sing N N 369 
MET CE    HE2    sing N N 370 
MET CE    HE3    sing N N 371 
MET OXT   HXT    sing N N 372 
PHE N     CA     sing N N 373 
PHE N     H      sing N N 374 
PHE N     H2     sing N N 375 
PHE CA    C      sing N N 376 
PHE CA    CB     sing N N 377 
PHE CA    HA     sing N N 378 
PHE C     O      doub N N 379 
PHE C     OXT    sing N N 380 
PHE CB    CG     sing N N 381 
PHE CB    HB2    sing N N 382 
PHE CB    HB3    sing N N 383 
PHE CG    CD1    doub Y N 384 
PHE CG    CD2    sing Y N 385 
PHE CD1   CE1    sing Y N 386 
PHE CD1   HD1    sing N N 387 
PHE CD2   CE2    doub Y N 388 
PHE CD2   HD2    sing N N 389 
PHE CE1   CZ     doub Y N 390 
PHE CE1   HE1    sing N N 391 
PHE CE2   CZ     sing Y N 392 
PHE CE2   HE2    sing N N 393 
PHE CZ    HZ     sing N N 394 
PHE OXT   HXT    sing N N 395 
PRO N     CA     sing N N 396 
PRO N     CD     sing N N 397 
PRO N     H      sing N N 398 
PRO CA    C      sing N N 399 
PRO CA    CB     sing N N 400 
PRO CA    HA     sing N N 401 
PRO C     O      doub N N 402 
PRO C     OXT    sing N N 403 
PRO CB    CG     sing N N 404 
PRO CB    HB2    sing N N 405 
PRO CB    HB3    sing N N 406 
PRO CG    CD     sing N N 407 
PRO CG    HG2    sing N N 408 
PRO CG    HG3    sing N N 409 
PRO CD    HD2    sing N N 410 
PRO CD    HD3    sing N N 411 
PRO OXT   HXT    sing N N 412 
SER N     CA     sing N N 413 
SER N     H      sing N N 414 
SER N     H2     sing N N 415 
SER CA    C      sing N N 416 
SER CA    CB     sing N N 417 
SER CA    HA     sing N N 418 
SER C     O      doub N N 419 
SER C     OXT    sing N N 420 
SER CB    OG     sing N N 421 
SER CB    HB2    sing N N 422 
SER CB    HB3    sing N N 423 
SER OG    HG     sing N N 424 
SER OXT   HXT    sing N N 425 
THR N     CA     sing N N 426 
THR N     H      sing N N 427 
THR N     H2     sing N N 428 
THR CA    C      sing N N 429 
THR CA    CB     sing N N 430 
THR CA    HA     sing N N 431 
THR C     O      doub N N 432 
THR C     OXT    sing N N 433 
THR CB    OG1    sing N N 434 
THR CB    CG2    sing N N 435 
THR CB    HB     sing N N 436 
THR OG1   HG1    sing N N 437 
THR CG2   HG21   sing N N 438 
THR CG2   HG22   sing N N 439 
THR CG2   HG23   sing N N 440 
THR OXT   HXT    sing N N 441 
TRP N     CA     sing N N 442 
TRP N     H      sing N N 443 
TRP N     H2     sing N N 444 
TRP CA    C      sing N N 445 
TRP CA    CB     sing N N 446 
TRP CA    HA     sing N N 447 
TRP C     O      doub N N 448 
TRP C     OXT    sing N N 449 
TRP CB    CG     sing N N 450 
TRP CB    HB2    sing N N 451 
TRP CB    HB3    sing N N 452 
TRP CG    CD1    doub Y N 453 
TRP CG    CD2    sing Y N 454 
TRP CD1   NE1    sing Y N 455 
TRP CD1   HD1    sing N N 456 
TRP CD2   CE2    doub Y N 457 
TRP CD2   CE3    sing Y N 458 
TRP NE1   CE2    sing Y N 459 
TRP NE1   HE1    sing N N 460 
TRP CE2   CZ2    sing Y N 461 
TRP CE3   CZ3    doub Y N 462 
TRP CE3   HE3    sing N N 463 
TRP CZ2   CH2    doub Y N 464 
TRP CZ2   HZ2    sing N N 465 
TRP CZ3   CH2    sing Y N 466 
TRP CZ3   HZ3    sing N N 467 
TRP CH2   HH2    sing N N 468 
TRP OXT   HXT    sing N N 469 
TYR N     CA     sing N N 470 
TYR N     H      sing N N 471 
TYR N     H2     sing N N 472 
TYR CA    C      sing N N 473 
TYR CA    CB     sing N N 474 
TYR CA    HA     sing N N 475 
TYR C     O      doub N N 476 
TYR C     OXT    sing N N 477 
TYR CB    CG     sing N N 478 
TYR CB    HB2    sing N N 479 
TYR CB    HB3    sing N N 480 
TYR CG    CD1    doub Y N 481 
TYR CG    CD2    sing Y N 482 
TYR CD1   CE1    sing Y N 483 
TYR CD1   HD1    sing N N 484 
TYR CD2   CE2    doub Y N 485 
TYR CD2   HD2    sing N N 486 
TYR CE1   CZ     doub Y N 487 
TYR CE1   HE1    sing N N 488 
TYR CE2   CZ     sing Y N 489 
TYR CE2   HE2    sing N N 490 
TYR CZ    OH     sing N N 491 
TYR OH    HH     sing N N 492 
TYR OXT   HXT    sing N N 493 
VAL N     CA     sing N N 494 
VAL N     H      sing N N 495 
VAL N     H2     sing N N 496 
VAL CA    C      sing N N 497 
VAL CA    CB     sing N N 498 
VAL CA    HA     sing N N 499 
VAL C     O      doub N N 500 
VAL C     OXT    sing N N 501 
VAL CB    CG1    sing N N 502 
VAL CB    CG2    sing N N 503 
VAL CB    HB     sing N N 504 
VAL CG1   HG11   sing N N 505 
VAL CG1   HG12   sing N N 506 
VAL CG1   HG13   sing N N 507 
VAL CG2   HG21   sing N N 508 
VAL CG2   HG22   sing N N 509 
VAL CG2   HG23   sing N N 510 
VAL OXT   HXT    sing N N 511 
# 
_ndb_struct_conf_na.entry_id   9OA4 
_ndb_struct_conf_na.feature    'double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A DT 3  1_555 B DA 15 1_555 -0.031 -0.143 -0.039 -0.750  -11.701 1.328  1  C_DT3:DA31_D  C 3  ? D 31 ? 20 1 
1 A DA 4  1_555 B DT 14 1_555 0.019  -0.072 -0.057 -0.296  -6.368  5.021  2  C_DA4:DT30_D  C 4  ? D 30 ? 20 1 
1 A DA 5  1_555 B DT 13 1_555 0.021  -0.112 0.014  6.845   -9.235  2.752  3  C_DA5:DT29_D  C 5  ? D 29 ? 20 1 
1 A DG 6  1_555 B DC 12 1_555 -0.317 -0.174 -0.155 1.184   -8.108  1.563  4  C_DG6:DC28_D  C 6  ? D 28 ? 19 1 
1 A DC 7  1_555 B DG 11 1_555 0.287  -0.140 0.167  -11.648 1.009   1.507  5  C_DC7:DG27_D  C 7  ? D 27 ? 19 1 
1 A DG 8  1_555 B DC 10 1_555 -0.260 -0.141 -0.189 4.960   -0.771  3.118  6  C_DG8:DC26_D  C 8  ? D 26 ? 19 1 
1 A DG 9  1_555 B DT 9  1_555 -2.419 -0.656 -0.232 12.062  -5.098  -8.523 7  C_DG9:DT25_D  C 9  ? D 25 ? 28 1 
1 A DA 10 1_555 B DT 8  1_555 0.004  -0.132 0.064  11.628  -17.949 2.894  8  C_DA10:DT24_D C 10 ? D 24 ? 20 1 
1 A DA 11 1_555 B DT 7  1_555 0.112  -0.152 0.092  6.426   -17.802 4.632  9  C_DA11:DT23_D C 11 ? D 23 ? 20 1 
1 A DG 12 1_555 B DC 6  1_555 -0.193 -0.121 0.037  -5.708  -15.122 -0.421 10 C_DG12:DC22_D C 12 ? D 22 ? 19 1 
1 A DT 13 1_555 B DA 5  1_555 -0.083 -0.140 0.076  -4.219  -10.299 3.756  11 C_DT13:DA21_D C 13 ? D 21 ? 20 1 
1 A DG 14 1_555 B DC 4  1_555 0.461  -3.442 -0.619 13.138  4.608   70.459 12 C_DG14:DC20_D C 14 ? D 20 ? ?  ? 
1 A DG 15 1_555 B DC 3  1_555 -0.181 -0.155 -0.009 -0.577  -9.903  0.118  13 C_DG15:DC19_D C 15 ? D 19 ? 19 1 
1 A DG 16 1_555 B DC 2  1_555 -0.309 -0.149 -0.152 -12.012 -11.583 0.321  14 C_DG16:DC18_D C 16 ? D 18 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A DT 3  1_555 B DA 15 1_555 A DA 4  1_555 B DT 14 1_555 0.236  -0.536 3.284  -0.225   8.568   29.086   -2.724 -0.496 3.006  
16.611  0.436   30.296   1  CC_DT3DA4:DT30DA31_DD   C 3  ? D 31 ? C 4  ? D 30 ? 
1 A DA 4  1_555 B DT 14 1_555 A DA 5  1_555 B DT 13 1_555 -0.415 -0.159 3.196  -1.174   2.732   32.950   -0.729 0.535  3.185  
4.805   2.064   33.080   2  CC_DA4DA5:DT29DT30_DD   C 4  ? D 30 ? C 5  ? D 29 ? 
1 A DA 5  1_555 B DT 13 1_555 A DG 6  1_555 B DC 12 1_555 0.474  -1.013 3.503  -0.977   5.819   29.909   -3.134 -1.105 3.236  
11.138  1.869   30.472   3  CC_DA5DG6:DC28DT29_DD   C 5  ? D 29 ? C 6  ? D 28 ? 
1 A DG 6  1_555 B DC 12 1_555 A DC 7  1_555 B DG 11 1_555 -0.056 -1.297 3.666  -2.558   5.744   32.901   -3.283 -0.363 3.393  
10.027  4.465   33.480   4  CC_DG6DC7:DG27DC28_DD   C 6  ? D 28 ? C 7  ? D 27 ? 
1 A DC 7  1_555 B DG 11 1_555 A DG 8  1_555 B DC 10 1_555 0.175  -0.429 3.055  4.062    6.070   26.845   -2.240 0.538  2.885  
12.776  -8.551  27.804   5  CC_DC7DG8:DC26DG27_DD   C 7  ? D 27 ? C 8  ? D 26 ? 
1 A DG 8  1_555 B DC 10 1_555 A DG 9  1_555 B DT 9  1_555 -2.193 -0.257 3.160  -6.986   5.555   24.393   -2.182 2.857  3.501  
12.618  15.871  25.951   6  CC_DG8DG9:DT25DC26_DD   C 8  ? D 26 ? C 9  ? D 25 ? 
1 A DG 9  1_555 B DT 9  1_555 A DA 10 1_555 B DT 8  1_555 1.070  -0.323 3.419  -1.719   3.954   40.956   -0.901 -1.713 3.329  
5.632   2.449   41.172   7  CC_DG9DA10:DT24DT25_DD  C 9  ? D 25 ? C 10 ? D 24 ? 
1 A DA 10 1_555 B DT 8  1_555 A DA 11 1_555 B DT 7  1_555 0.265  -0.361 3.364  1.519    4.834   31.692   -1.541 -0.200 3.283  
8.781   -2.760  32.085   8  CC_DA10DA11:DT23DT24_DD C 10 ? D 24 ? C 11 ? D 23 ? 
1 A DA 11 1_555 B DT 7  1_555 A DG 12 1_555 B DC 6  1_555 -0.363 -0.856 3.549  -4.355   5.450   39.935   -1.891 0.001  3.427  
7.906   6.318   40.515   9  CC_DA11DG12:DC22DT23_DD C 11 ? D 23 ? C 12 ? D 22 ? 
1 A DG 12 1_555 B DC 6  1_555 A DT 13 1_555 B DA 5  1_555 -1.026 -0.961 3.259  -0.448   2.009   25.800   -2.696 2.169  3.193  
4.491   1.001   25.881   10 CC_DG12DT13:DA21DC22_DD C 12 ? D 22 ? C 13 ? D 21 ? 
1 A DT 13 1_555 B DA 5  1_555 A DG 14 1_555 B DC 4  1_555 -2.176 3.530  -0.997 174.333  -15.991 -123.578 -1.773 -1.176 0.298  
8.022   87.458  -177.668 11 CC_DT13DG14:DC20DA21_DD C 13 ? D 21 ? C 14 ? D 20 ? 
1 A DG 14 1_555 B DC 4  1_555 A DG 15 1_555 B DC 3  1_555 0.254  3.866  -0.799 -136.192 106.390 -172.707 -1.916 0.149  -0.936 
-53.200 -68.102 -179.544 12 CC_DG14DG15:DC19DC20_DD C 14 ? D 20 ? C 15 ? D 19 ? 
1 A DG 15 1_555 B DC 3  1_555 A DG 16 1_555 B DC 2  1_555 0.896  -0.447 3.604  2.884    1.723   30.707   -1.211 -1.060 3.641  
3.241   -5.425  30.886   13 CC_DG15DG16:DC18DC19_DD C 15 ? D 19 ? C 16 ? D 18 ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of Environmental Health Sciences (NIH/NIEHS)' 'United States' ES035139 1 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'           'United States' HL155178 2 
'National Science Foundation (NSF, United States)'                                              'United States' 2028902  3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8E3K 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9OA4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.023184 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.011606 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.016476 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.024961 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    O "O5'"  . DA  A 1 1  ? 3.69812   1.33708   32.98860  1.000 28.86978 ? 1   DA  C "O5'"  1 
ATOM   2    C "C5'"  . DA  A 1 1  ? 3.61854   2.14717   34.14614  1.000 29.57256 ? 1   DA  C "C5'"  1 
ATOM   3    C "C4'"  . DA  A 1 1  ? 4.50711   3.36931   34.00503  1.000 27.49287 ? 1   DA  C "C4'"  1 
ATOM   4    O "O4'"  . DA  A 1 1  ? 5.89519   2.98669   34.19834  1.000 25.90889 ? 1   DA  C "O4'"  1 
ATOM   5    C "C3'"  . DA  A 1 1  ? 4.44360   4.04881   32.64586  1.000 26.66547 ? 1   DA  C "C3'"  1 
ATOM   6    O "O3'"  . DA  A 1 1  ? 4.51820   5.45251   32.80816  1.000 27.41201 ? 1   DA  C "O3'"  1 
ATOM   7    C "C2'"  . DA  A 1 1  ? 5.65307   3.47895   31.90728  1.000 25.55975 ? 1   DA  C "C2'"  1 
ATOM   8    C "C1'"  . DA  A 1 1  ? 6.65511   3.22737   33.02506  1.000 26.71736 ? 1   DA  C "C1'"  1 
ATOM   9    N N9     . DA  A 1 1  ? 7.52676   2.06915   32.81604  1.000 24.49084 ? 1   DA  C N9     1 
ATOM   10   C C8     . DA  A 1 1  ? 7.21060   0.76302   33.05709  1.000 26.56430 ? 1   DA  C C8     1 
ATOM   11   N N7     . DA  A 1 1  ? 8.18651   -0.07177  32.80655  1.000 23.52395 ? 1   DA  C N7     1 
ATOM   12   C C5     . DA  A 1 1  ? 9.21510   0.74073   32.36527  1.000 20.83209 ? 1   DA  C C5     1 
ATOM   13   C C6     . DA  A 1 1  ? 10.52019  0.45117   31.95833  1.000 18.64019 ? 1   DA  C C6     1 
ATOM   14   N N6     . DA  A 1 1  ? 11.01316  -0.79043  31.92474  1.000 19.44207 ? 1   DA  C N6     1 
ATOM   15   N N1     . DA  A 1 1  ? 11.29921  1.48303   31.56669  1.000 19.43984 ? 1   DA  C N1     1 
ATOM   16   C C2     . DA  A 1 1  ? 10.80785  2.72168   31.63034  1.000 21.53232 ? 1   DA  C C2     1 
ATOM   17   N N3     . DA  A 1 1  ? 9.58970   3.12102   32.01116  1.000 22.06773 ? 1   DA  C N3     1 
ATOM   18   C C4     . DA  A 1 1  ? 8.83759   2.06470   32.37472  1.000 21.16154 ? 1   DA  C C4     1 
ATOM   19   H "H5'"  . DA  A 1 1  ? 3.90168   1.63228   34.91790  1.000 35.48707 ? 1   DA  C "H5'"  1 
ATOM   20   H "H5''" . DA  A 1 1  ? 2.70031   2.43163   34.27589  1.000 35.48707 ? 1   DA  C "H5''" 1 
ATOM   21   H "H4'"  . DA  A 1 1  ? 4.27097   4.01619   34.68818  1.000 32.99145 ? 1   DA  C "H4'"  1 
ATOM   22   H "H3'"  . DA  A 1 1  ? 3.63219   3.80057   32.17586  1.000 31.99856 ? 1   DA  C "H3'"  1 
ATOM   23   H "H2'"  . DA  A 1 1  ? 5.42656   2.65499   31.44828  1.000 30.67170 ? 1   DA  C "H2'"  1 
ATOM   24   H "H2''" . DA  A 1 1  ? 6.00060   4.11454   31.26219  1.000 30.67170 ? 1   DA  C "H2''" 1 
ATOM   25   H "H1'"  . DA  A 1 1  ? 7.20069   4.02223   33.13204  1.000 32.06083 ? 1   DA  C "H1'"  1 
ATOM   26   H H8     . DA  A 1 1  ? 6.37814   0.49161   33.37053  1.000 31.87716 ? 1   DA  C H8     1 
ATOM   27   H H61    . DA  A 1 1  ? 11.81867  -0.92613  31.65578  1.000 23.33048 ? 1   DA  C H61    1 
ATOM   28   H H62    . DA  A 1 1  ? 10.52491  -1.45378  32.17209  1.000 23.33048 ? 1   DA  C H62    1 
ATOM   29   H H2     . DA  A 1 1  ? 11.39156  3.39928   31.37532  1.000 25.83879 ? 1   DA  C H2     1 
ATOM   30   H "HO5'" . DA  A 1 1  ? 4.44044   1.03472   32.73685  1.000 34.64374 ? 1   DA  C "HO5'" 1 
ATOM   31   P P      . DA  A 1 2  ? 4.03448   6.43741   31.64915  1.000 28.85165 ? 2   DA  C P      1 
ATOM   32   O OP1    . DA  A 1 2  ? 3.75736   7.73414   32.31089  1.000 32.75054 ? 2   DA  C OP1    1 
ATOM   33   O OP2    . DA  A 1 2  ? 2.97169   5.76446   30.86875  1.000 30.71857 ? 2   DA  C OP2    1 
ATOM   34   O "O5'"  . DA  A 1 2  ? 5.31432   6.58603   30.70265  1.000 27.08394 ? 2   DA  C "O5'"  1 
ATOM   35   C "C5'"  . DA  A 1 2  ? 6.42624   7.33943   31.14569  1.000 26.37310 ? 2   DA  C "C5'"  1 
ATOM   36   C "C4'"  . DA  A 1 2  ? 7.48618   7.42529   30.06400  1.000 27.18088 ? 2   DA  C "C4'"  1 
ATOM   37   O "O4'"  . DA  A 1 2  ? 8.17209   6.16632   29.97263  1.000 27.06966 ? 2   DA  C "O4'"  1 
ATOM   38   C "C3'"  . DA  A 1 2  ? 6.96497   7.72229   28.65553  1.000 29.50089 ? 2   DA  C "C3'"  1 
ATOM   39   O "O3'"  . DA  A 1 2  ? 7.78012   8.72071   28.05702  1.000 35.59983 ? 2   DA  C "O3'"  1 
ATOM   40   C "C2'"  . DA  A 1 2  ? 7.05785   6.37047   27.94112  1.000 26.80814 ? 2   DA  C "C2'"  1 
ATOM   41   C "C1'"  . DA  A 1 2  ? 8.26927   5.76703   28.61505  1.000 24.88869 ? 2   DA  C "C1'"  1 
ATOM   42   N N9     . DA  A 1 2  ? 8.34099   4.32274   28.61701  1.000 22.64937 ? 2   DA  C N9     1 
ATOM   43   C C8     . DA  A 1 2  ? 7.33475   3.44736   28.93842  1.000 22.78215 ? 2   DA  C C8     1 
ATOM   44   N N7     . DA  A 1 2  ? 7.70702   2.19098   28.92209  1.000 22.89772 ? 2   DA  C N7     1 
ATOM   45   C C5     . DA  A 1 2  ? 9.06357   2.25006   28.59670  1.000 20.85646 ? 2   DA  C C5     1 
ATOM   46   C C6     . DA  A 1 2  ? 10.03758  1.25078   28.42437  1.000 20.29116 ? 2   DA  C C6     1 
ATOM   47   N N6     . DA  A 1 2  ? 9.78740   -0.04803  28.58133  1.000 19.69060 ? 2   DA  C N6     1 
ATOM   48   N N1     . DA  A 1 2  ? 11.28580  1.63969   28.07558  1.000 20.12267 ? 2   DA  C N1     1 
ATOM   49   C C2     . DA  A 1 2  ? 11.53893  2.94396   27.92576  1.000 22.34348 ? 2   DA  C C2     1 
ATOM   50   N N3     . DA  A 1 2  ? 10.70949  3.97635   28.07910  1.000 23.80651 ? 2   DA  C N3     1 
ATOM   51   C C4     . DA  A 1 2  ? 9.47013   3.55274   28.41309  1.000 22.17868 ? 2   DA  C C4     1 
ATOM   52   H "H5'"  . DA  A 1 2  ? 6.80566   6.91696   31.93212  1.000 31.64772 ? 2   DA  C "H5'"  1 
ATOM   53   H "H5''" . DA  A 1 2  ? 6.13363   8.23453   31.37820  1.000 31.64772 ? 2   DA  C "H5''" 1 
ATOM   54   H "H4'"  . DA  A 1 2  ? 8.12488   8.11502   30.30323  1.000 32.61706 ? 2   DA  C "H4'"  1 
ATOM   55   H "H3'"  . DA  A 1 2  ? 6.03611   8.00078   28.67933  1.000 35.40107 ? 2   DA  C "H3'"  1 
ATOM   56   H "H2'"  . DA  A 1 2  ? 6.26309   5.83366   28.08633  1.000 32.16977 ? 2   DA  C "H2'"  1 
ATOM   57   H "H2''" . DA  A 1 2  ? 7.19589   6.47867   26.98711  1.000 32.16977 ? 2   DA  C "H2''" 1 
ATOM   58   H "H1'"  . DA  A 1 2  ? 9.06164   6.11627   28.17793  1.000 29.86643 ? 2   DA  C "H1'"  1 
ATOM   59   H H8     . DA  A 1 2  ? 6.47056   3.71968   29.14798  1.000 27.33858 ? 2   DA  C H8     1 
ATOM   60   H H61    . DA  A 1 2  ? 10.41435  -0.62430  28.46115  1.000 23.62872 ? 2   DA  C H61    1 
ATOM   61   H H62    . DA  A 1 2  ? 8.99891   -0.31035  28.80285  1.000 23.62872 ? 2   DA  C H62    1 
ATOM   62   H H2     . DA  A 1 2  ? 12.41006  3.15985   27.68200  1.000 26.81217 ? 2   DA  C H2     1 
ATOM   63   P P      . DT  A 1 3  ? 7.43099   9.30906   26.60721  1.000 41.73884 ? 3   DT  C P      1 
ATOM   64   O OP1    . DT  A 1 3  ? 7.87686   10.71614  26.60060  1.000 45.32870 ? 3   DT  C OP1    1 
ATOM   65   O OP2    . DT  A 1 3  ? 6.01817   8.96900   26.30800  1.000 45.11224 ? 3   DT  C OP2    1 
ATOM   66   O "O5'"  . DT  A 1 3  ? 8.35842   8.45964   25.62981  1.000 39.92500 ? 3   DT  C "O5'"  1 
ATOM   67   C "C5'"  . DT  A 1 3  ? 9.74493   8.42753   25.85523  1.000 37.10448 ? 3   DT  C "C5'"  1 
ATOM   68   C "C4'"  . DT  A 1 3  ? 10.40664  7.40928   24.95938  1.000 35.82187 ? 3   DT  C "C4'"  1 
ATOM   69   O "O4'"  . DT  A 1 3  ? 10.09640  6.08615   25.40754  1.000 33.08079 ? 3   DT  C "O4'"  1 
ATOM   70   C "C3'"  . DT  A 1 3  ? 9.95855   7.45649   23.50041  1.000 37.18152 ? 3   DT  C "C3'"  1 
ATOM   71   O "O3'"  . DT  A 1 3  ? 11.00761  7.94666   22.71692  1.000 40.60642 ? 3   DT  C "O3'"  1 
ATOM   72   C "C2'"  . DT  A 1 3  ? 9.58815   6.00417   23.15836  1.000 33.86533 ? 3   DT  C "C2'"  1 
ATOM   73   C "C1'"  . DT  A 1 3  ? 10.21051  5.22975   24.30046  1.000 31.57231 ? 3   DT  C "C1'"  1 
ATOM   74   N N1     . DT  A 1 3  ? 9.56059   3.94451   24.64661  1.000 28.74590 ? 3   DT  C N1     1 
ATOM   75   C C2     . DT  A 1 3  ? 10.30424  2.79768   24.60047  1.000 27.65213 ? 3   DT  C C2     1 
ATOM   76   O O2     . DT  A 1 3  ? 11.46380  2.76868   24.24658  1.000 27.75158 ? 3   DT  C O2     1 
ATOM   77   N N3     . DT  A 1 3  ? 9.64180   1.67447   24.98412  1.000 25.07787 ? 3   DT  C N3     1 
ATOM   78   C C4     . DT  A 1 3  ? 8.33059   1.57577   25.39648  1.000 25.40412 ? 3   DT  C C4     1 
ATOM   79   O O4     . DT  A 1 3  ? 7.83222   0.50047   25.71062  1.000 25.78547 ? 3   DT  C O4     1 
ATOM   80   C C5     . DT  A 1 3  ? 7.59000   2.81530   25.41085  1.000 26.45903 ? 3   DT  C C5     1 
ATOM   81   C C7     . DT  A 1 3  ? 6.14601   2.83455   25.83613  1.000 28.21050 ? 3   DT  C C7     1 
ATOM   82   C C6     . DT  A 1 3  ? 8.24013   3.93273   25.05788  1.000 28.76656 ? 3   DT  C C6     1 
ATOM   83   H "H5'"  . DT  A 1 3  ? 9.91358   8.19653   26.78211  1.000 44.52538 ? 3   DT  C "H5'"  1 
ATOM   84   H "H5''" . DT  A 1 3  ? 10.11921  9.30409   25.67510  1.000 44.52538 ? 3   DT  C "H5''" 1 
ATOM   85   H "H4'"  . DT  A 1 3  ? 11.36770  7.53233   25.00563  1.000 42.98624 ? 3   DT  C "H4'"  1 
ATOM   86   H "H3'"  . DT  A 1 3  ? 9.16196   8.00218   23.40781  1.000 44.61783 ? 3   DT  C "H3'"  1 
ATOM   87   H "H2'"  . DT  A 1 3  ? 8.62618   5.88234   23.13264  1.000 40.63840 ? 3   DT  C "H2'"  1 
ATOM   88   H "H2''" . DT  A 1 3  ? 9.96334   5.73625   22.30493  1.000 40.63840 ? 3   DT  C "H2''" 1 
ATOM   89   H "H1'"  . DT  A 1 3  ? 11.13596  5.03778   24.08232  1.000 37.88677 ? 3   DT  C "H1'"  1 
ATOM   90   H H3     . DT  A 1 3  ? 10.09223  0.94205   24.96764  1.000 30.09344 ? 3   DT  C H3     1 
ATOM   91   H H71    . DT  A 1 3  ? 6.01999   3.53577   26.49440  1.000 33.85260 ? 3   DT  C H71    1 
ATOM   92   H H72    . DT  A 1 3  ? 5.59039   3.00598   25.05973  1.000 33.85260 ? 3   DT  C H72    1 
ATOM   93   H H73    . DT  A 1 3  ? 5.91891   1.97403   26.22191  1.000 33.85260 ? 3   DT  C H73    1 
ATOM   94   H H6     . DT  A 1 3  ? 7.78051   4.74052   25.09114  1.000 34.51987 ? 3   DT  C H6     1 
ATOM   95   P P      . DA  A 1 4  ? 10.79736  8.23556   21.15340  1.000 44.78668 ? 4   DA  C P      1 
ATOM   96   O OP1    . DA  A 1 4  ? 11.78384  9.26300   20.76807  1.000 49.17592 ? 4   DA  C OP1    1 
ATOM   97   O OP2    . DA  A 1 4  ? 9.35463   8.46899   20.90560  1.000 47.58728 ? 4   DA  C OP2    1 
ATOM   98   O "O5'"  . DA  A 1 4  ? 11.19067  6.85832   20.45789  1.000 40.05542 ? 4   DA  C "O5'"  1 
ATOM   99   C "C5'"  . DA  A 1 4  ? 12.44727  6.29169   20.71722  1.000 38.10601 ? 4   DA  C "C5'"  1 
ATOM   100  C "C4'"  . DA  A 1 4  ? 12.55073  4.92899   20.09170  1.000 33.56801 ? 4   DA  C "C4'"  1 
ATOM   101  O "O4'"  . DA  A 1 4  ? 11.78153  3.98321   20.85540  1.000 32.10871 ? 4   DA  C "O4'"  1 
ATOM   102  C "C3'"  . DA  A 1 4  ? 12.02434  4.85517   18.66613  1.000 34.82244 ? 4   DA  C "C3'"  1 
ATOM   103  O "O3'"  . DA  A 1 4  ? 13.10900  4.55386   17.79697  1.000 37.14946 ? 4   DA  C "O3'"  1 
ATOM   104  C "C2'"  . DA  A 1 4  ? 10.94029  3.76121   18.71296  1.000 35.81870 ? 4   DA  C "C2'"  1 
ATOM   105  C "C1'"  . DA  A 1 4  ? 11.27522  3.00945   19.99600  1.000 34.24148 ? 4   DA  C "C1'"  1 
ATOM   106  N N9     . DA  A 1 4  ? 10.15783  2.34146   20.68529  1.000 33.68426 ? 4   DA  C N9     1 
ATOM   107  C C8     . DA  A 1 4  ? 9.00970   2.90829   21.16362  1.000 34.03755 ? 4   DA  C C8     1 
ATOM   108  N N7     . DA  A 1 4  ? 8.21430   2.05811   21.78408  1.000 33.02993 ? 4   DA  C N7     1 
ATOM   109  C C5     . DA  A 1 4  ? 8.89765   0.85810   21.72913  1.000 31.81185 ? 4   DA  C C5     1 
ATOM   110  C C6     . DA  A 1 4  ? 8.60086   -0.44256  22.21759  1.000 30.61761 ? 4   DA  C C6     1 
ATOM   111  N N6     . DA  A 1 4  ? 7.48098   -0.75445  22.87028  1.000 31.36939 ? 4   DA  C N6     1 
ATOM   112  N N1     . DA  A 1 4  ? 9.50308   -1.41492  21.99199  1.000 29.79063 ? 4   DA  C N1     1 
ATOM   113  C C2     . DA  A 1 4  ? 10.62681  -1.10967  21.33388  1.000 30.25338 ? 4   DA  C C2     1 
ATOM   114  N N3     . DA  A 1 4  ? 11.02119  0.07060   20.83982  1.000 31.32671 ? 4   DA  C N3     1 
ATOM   115  C C4     . DA  A 1 4  ? 10.10339  1.01746   21.06921  1.000 32.29291 ? 4   DA  C C4     1 
ATOM   116  H "H5'"  . DA  A 1 4  ? 12.57301  6.21505   21.67597  1.000 45.72721 ? 4   DA  C "H5'"  1 
ATOM   117  H "H5''" . DA  A 1 4  ? 13.13933  6.86541   20.35281  1.000 45.72721 ? 4   DA  C "H5''" 1 
ATOM   118  H "H4'"  . DA  A 1 4  ? 13.47570  4.63707   20.10257  1.000 40.28161 ? 4   DA  C "H4'"  1 
ATOM   119  H "H3'"  . DA  A 1 4  ? 11.59152  5.68355   18.40660  1.000 41.78693 ? 4   DA  C "H3'"  1 
ATOM   120  H "H2'"  . DA  A 1 4  ? 10.05183  4.14830   18.75409  1.000 42.98244 ? 4   DA  C "H2'"  1 
ATOM   121  H "H2''" . DA  A 1 4  ? 10.99537  3.17843   17.93951  1.000 42.98244 ? 4   DA  C "H2''" 1 
ATOM   122  H "H1'"  . DA  A 1 4  ? 11.93139  2.32736   19.78364  1.000 41.08978 ? 4   DA  C "H1'"  1 
ATOM   123  H H8     . DA  A 1 4  ? 8.80780   3.81031   21.06111  1.000 40.84506 ? 4   DA  C H8     1 
ATOM   124  H H61    . DA  A 1 4  ? 7.34887   -1.56154  23.13627  1.000 37.64327 ? 4   DA  C H61    1 
ATOM   125  H H62    . DA  A 1 4  ? 6.89069   -0.14855  23.02531  1.000 37.64327 ? 4   DA  C H62    1 
ATOM   126  H H2     . DA  A 1 4  ? 11.21680  -1.81615  21.20084  1.000 36.30406 ? 4   DA  C H2     1 
ATOM   127  P P      . DA  A 1 5  ? 12.94422  4.56773   16.20275  1.000 38.27277 ? 5   DA  C P      1 
ATOM   128  O OP1    . DA  A 1 5  ? 14.17041  5.20641   15.67697  1.000 42.50877 ? 5   DA  C OP1    1 
ATOM   129  O OP2    . DA  A 1 5  ? 11.61635  5.10143   15.83189  1.000 38.41575 ? 5   DA  C OP2    1 
ATOM   130  O "O5'"  . DA  A 1 5  ? 12.94280  3.02248   15.83370  1.000 36.16500 ? 5   DA  C "O5'"  1 
ATOM   131  C "C5'"  . DA  A 1 5  ? 14.04381  2.23606   16.17716  1.000 32.66697 ? 5   DA  C "C5'"  1 
ATOM   132  C "C4'"  . DA  A 1 5  ? 13.73227  0.76945   16.03384  1.000 29.45919 ? 5   DA  C "C4'"  1 
ATOM   133  O "O4'"  . DA  A 1 5  ? 12.65847  0.40668   16.94003  1.000 28.81873 ? 5   DA  C "O4'"  1 
ATOM   134  C "C3'"  . DA  A 1 5  ? 13.28163  0.34039   14.63578  1.000 28.73375 ? 5   DA  C "C3'"  1 
ATOM   135  O "O3'"  . DA  A 1 5  ? 14.12580  -0.73099  14.19328  1.000 28.39106 ? 5   DA  C "O3'"  1 
ATOM   136  C "C2'"  . DA  A 1 5  ? 11.80815  -0.05665  14.83146  1.000 28.13913 ? 5   DA  C "C2'"  1 
ATOM   137  C "C1'"  . DA  A 1 5  ? 11.76638  -0.45362  16.29782  1.000 27.24907 ? 5   DA  C "C1'"  1 
ATOM   138  N N9     . DA  A 1 5  ? 10.47428  -0.31920  16.97391  1.000 25.59886 ? 5   DA  C N9     1 
ATOM   139  C C8     . DA  A 1 5  ? 9.70206   0.80247   17.10025  1.000 26.41933 ? 5   DA  C C8     1 
ATOM   140  N N7     . DA  A 1 5  ? 8.61406   0.62081   17.82245  1.000 26.09688 ? 5   DA  C N7     1 
ATOM   141  C C5     . DA  A 1 5  ? 8.68525   -0.71053  18.19321  1.000 24.00343 ? 5   DA  C C5     1 
ATOM   142  C C6     . DA  A 1 5  ? 7.85939   -1.53000  18.99332  1.000 23.80682 ? 5   DA  C C6     1 
ATOM   143  N N6     . DA  A 1 5  ? 6.70826   -1.12069  19.53639  1.000 24.04228 ? 5   DA  C N6     1 
ATOM   144  N N1     . DA  A 1 5  ? 8.24161   -2.80938  19.18311  1.000 23.99668 ? 5   DA  C N1     1 
ATOM   145  C C2     . DA  A 1 5  ? 9.38771   -3.22964  18.63795  1.000 25.84456 ? 5   DA  C C2     1 
ATOM   146  N N3     . DA  A 1 5  ? 10.25120  -2.55552  17.88097  1.000 26.17441 ? 5   DA  C N3     1 
ATOM   147  C C4     . DA  A 1 5  ? 9.84564   -1.28954  17.70626  1.000 25.44201 ? 5   DA  C C4     1 
ATOM   148  H "H5'"  . DA  A 1 5  ? 14.29187  2.42023   17.09664  1.000 39.20037 ? 5   DA  C "H5'"  1 
ATOM   149  H "H5''" . DA  A 1 5  ? 14.78864  2.46117   15.59798  1.000 39.20037 ? 5   DA  C "H5''" 1 
ATOM   150  H "H4'"  . DA  A 1 5  ? 14.51655  0.25236   16.27557  1.000 35.35102 ? 5   DA  C "H4'"  1 
ATOM   151  H "H3'"  . DA  A 1 5  ? 13.30688  1.07702   14.00520  1.000 34.48050 ? 5   DA  C "H3'"  1 
ATOM   152  H "H2'"  . DA  A 1 5  ? 11.21504  0.68941   14.65114  1.000 33.76695 ? 5   DA  C "H2'"  1 
ATOM   153  H "H2''" . DA  A 1 5  ? 11.56412  -0.79988  14.25790  1.000 33.76695 ? 5   DA  C "H2''" 1 
ATOM   154  H "H1'"  . DA  A 1 5  ? 12.04314  -1.38116  16.36098  1.000 32.69889 ? 5   DA  C "H1'"  1 
ATOM   155  H H8     . DA  A 1 5  ? 9.92393   1.61814   16.71249  1.000 31.70320 ? 5   DA  C H8     1 
ATOM   156  H H61    . DA  A 1 5  ? 6.22997   -1.66921  19.99461  1.000 28.85074 ? 5   DA  C H61    1 
ATOM   157  H H62    . DA  A 1 5  ? 6.44610   -0.30890  19.42749  1.000 28.85074 ? 5   DA  C H62    1 
ATOM   158  H H2     . DA  A 1 5  ? 9.61300   -4.11512  18.81138  1.000 31.01347 ? 5   DA  C H2     1 
ATOM   159  P P      . DG  A 1 6  ? 14.08296  -1.31020  12.69382  1.000 27.91699 ? 6   DG  C P      1 
ATOM   160  O OP1    . DG  A 1 6  ? 15.34002  -2.10541  12.59811  1.000 31.20325 ? 6   DG  C OP1    1 
ATOM   161  O OP2    . DG  A 1 6  ? 13.84595  -0.24176  11.68771  1.000 31.11689 ? 6   DG  C OP2    1 
ATOM   162  O "O5'"  . DG  A 1 6  ? 12.86192  -2.32933  12.76955  1.000 27.52690 ? 6   DG  C "O5'"  1 
ATOM   163  C "C5'"  . DG  A 1 6  ? 13.07563  -3.53955  13.46071  1.000 26.62639 ? 6   DG  C "C5'"  1 
ATOM   164  C "C4'"  . DG  A 1 6  ? 11.81112  -4.34221  13.63014  1.000 27.50272 ? 6   DG  C "C4'"  1 
ATOM   165  O "O4'"  . DG  A 1 6  ? 10.86695  -3.62777  14.46163  1.000 25.96707 ? 6   DG  C "O4'"  1 
ATOM   166  C "C3'"  . DG  A 1 6  ? 11.06004  -4.66458  12.33407  1.000 28.77270 ? 6   DG  C "C3'"  1 
ATOM   167  O "O3'"  . DG  A 1 6  ? 11.20674  -6.06154  12.03645  1.000 29.47992 ? 6   DG  C "O3'"  1 
ATOM   168  C "C2'"  . DG  A 1 6  ? 9.60778   -4.26476  12.64597  1.000 27.89317 ? 6   DG  C "C2'"  1 
ATOM   169  C "C1'"  . DG  A 1 6  ? 9.62058   -4.14863  14.16976  1.000 27.36853 ? 6   DG  C "C1'"  1 
ATOM   170  N N9     . DG  A 1 6  ? 8.58788   -3.29292  14.73537  1.000 27.32328 ? 6   DG  C N9     1 
ATOM   171  C C8     . DG  A 1 6  ? 8.43542   -1.93303  14.58616  1.000 26.72935 ? 6   DG  C C8     1 
ATOM   172  N N7     . DG  A 1 6  ? 7.38684   -1.45719  15.21641  1.000 25.52622 ? 6   DG  C N7     1 
ATOM   173  C C5     . DG  A 1 6  ? 6.83139   -2.57658  15.83869  1.000 25.62157 ? 6   DG  C C5     1 
ATOM   174  C C6     . DG  A 1 6  ? 5.67287   -2.70007  16.64579  1.000 24.82847 ? 6   DG  C C6     1 
ATOM   175  O O6     . DG  A 1 6  ? 4.88297   -1.81481  17.01047  1.000 26.16841 ? 6   DG  C O6     1 
ATOM   176  N N1     . DG  A 1 6  ? 5.45195   -4.01748  17.02743  1.000 26.36482 ? 6   DG  C N1     1 
ATOM   177  C C2     . DG  A 1 6  ? 6.26163   -5.07842  16.69374  1.000 27.30179 ? 6   DG  C C2     1 
ATOM   178  N N2     . DG  A 1 6  ? 5.89602   -6.27680  17.15758  1.000 28.45724 ? 6   DG  C N2     1 
ATOM   179  N N3     . DG  A 1 6  ? 7.34355   -4.97627  15.93917  1.000 27.30540 ? 6   DG  C N3     1 
ATOM   180  C C4     . DG  A 1 6  ? 7.56299   -3.70549  15.54667  1.000 25.38502 ? 6   DG  C C4     1 
ATOM   181  H "H5'"  . DG  A 1 6  ? 13.43791  -3.33858  14.33779  1.000 31.95167 ? 6   DG  C "H5'"  1 
ATOM   182  H "H5''" . DG  A 1 6  ? 13.71951  -4.07149  12.96738  1.000 31.95167 ? 6   DG  C "H5''" 1 
ATOM   183  H "H4'"  . DG  A 1 6  ? 12.03840  -5.17325  14.07579  1.000 33.00326 ? 6   DG  C "H4'"  1 
ATOM   184  H "H3'"  . DG  A 1 6  ? 11.38292  -4.11988  11.59926  1.000 34.52724 ? 6   DG  C "H3'"  1 
ATOM   185  H "H2'"  . DG  A 1 6  ? 9.37692   -3.41975  12.22936  1.000 33.47180 ? 6   DG  C "H2'"  1 
ATOM   186  H "H2''" . DG  A 1 6  ? 8.98281   -4.94450  12.34887  1.000 33.47180 ? 6   DG  C "H2''" 1 
ATOM   187  H "H1'"  . DG  A 1 6  ? 9.51221   -5.02463  14.57200  1.000 32.84224 ? 6   DG  C "H1'"  1 
ATOM   188  H H8     . DG  A 1 6  ? 9.01691   -1.40445  14.08879  1.000 32.07522 ? 6   DG  C H8     1 
ATOM   189  H H1     . DG  A 1 6  ? 4.75779   -4.18190  17.50774  1.000 31.63778 ? 6   DG  C H1     1 
ATOM   190  H H21    . DG  A 1 6  ? 6.36262   -6.97307  16.96500  1.000 34.14868 ? 6   DG  C H21    1 
ATOM   191  H H22    . DG  A 1 6  ? 5.19408   -6.35193  17.64873  1.000 34.14868 ? 6   DG  C H22    1 
ATOM   192  P P      . DC  A 1 7  ? 10.65734  -6.70574  10.66888  1.000 29.67458 ? 7   DC  C P      1 
ATOM   193  O OP1    . DC  A 1 7  ? 11.44755  -7.93931  10.43406  1.000 31.39346 ? 7   DC  C OP1    1 
ATOM   194  O OP2    . DC  A 1 7  ? 10.47804  -5.68090  9.61830   1.000 29.32672 ? 7   DC  C OP2    1 
ATOM   195  O "O5'"  . DC  A 1 7  ? 9.18964   -7.14914  11.03513  1.000 27.99075 ? 7   DC  C "O5'"  1 
ATOM   196  C "C5'"  . DC  A 1 7  ? 9.00516   -8.15509  11.98624  1.000 28.48851 ? 7   DC  C "C5'"  1 
ATOM   197  C "C4'"  . DC  A 1 7  ? 7.54869   -8.31296  12.31083  1.000 27.49262 ? 7   DC  C "C4'"  1 
ATOM   198  O "O4'"  . DC  A 1 7  ? 7.07299   -7.14013  12.98405  1.000 26.28529 ? 7   DC  C "O4'"  1 
ATOM   199  C "C3'"  . DC  A 1 7  ? 6.62598   -8.45503  11.09989  1.000 29.70419 ? 7   DC  C "C3'"  1 
ATOM   200  O "O3'"  . DC  A 1 7  ? 6.41825   -9.80836  10.80474  1.000 34.39400 ? 7   DC  C "O3'"  1 
ATOM   201  C "C2'"  . DC  A 1 7  ? 5.33805   -7.74542  11.52482  1.000 29.07035 ? 7   DC  C "C2'"  1 
ATOM   202  C "C1'"  . DC  A 1 7  ? 5.67013   -7.17500  12.89675  1.000 26.21760 ? 7   DC  C "C1'"  1 
ATOM   203  N N1     . DC  A 1 7  ? 5.14649   -5.82617  13.13077  1.000 25.91833 ? 7   DC  C N1     1 
ATOM   204  C C2     . DC  A 1 7  ? 3.91187   -5.68908  13.75908  1.000 25.04797 ? 7   DC  C C2     1 
ATOM   205  O O2     . DC  A 1 7  ? 3.29021   -6.71252  14.08190  1.000 29.44439 ? 7   DC  C O2     1 
ATOM   206  N N3     . DC  A 1 7  ? 3.44113   -4.44839  14.01847  1.000 26.36275 ? 7   DC  C N3     1 
ATOM   207  C C4     . DC  A 1 7  ? 4.14401   -3.37988  13.65118  1.000 24.99050 ? 7   DC  C C4     1 
ATOM   208  N N4     . DC  A 1 7  ? 3.63037   -2.17448  13.91984  1.000 26.72523 ? 7   DC  C N4     1 
ATOM   209  C C5     . DC  A 1 7  ? 5.41059   -3.49593  12.98571  1.000 25.14564 ? 7   DC  C C5     1 
ATOM   210  C C6     . DC  A 1 7  ? 5.87310   -4.73013  12.75708  1.000 24.97012 ? 7   DC  C C6     1 
ATOM   211  H "H5'"  . DC  A 1 7  ? 9.49083   -7.92582  12.79399  1.000 34.18621 ? 7   DC  C "H5'"  1 
ATOM   212  H "H5''" . DC  A 1 7  ? 9.34885   -8.99268  11.63808  1.000 34.18621 ? 7   DC  C "H5''" 1 
ATOM   213  H "H4'"  . DC  A 1 7  ? 7.44738   -9.08415  12.89041  1.000 32.99115 ? 7   DC  C "H4'"  1 
ATOM   214  H "H3'"  . DC  A 1 7  ? 7.00863   -7.99207  10.33822  1.000 35.64502 ? 7   DC  C "H3'"  1 
ATOM   215  H "H2'"  . DC  A 1 7  ? 5.10910   -7.03866  10.90114  1.000 34.88442 ? 7   DC  C "H2'"  1 
ATOM   216  H "H2''" . DC  A 1 7  ? 4.59860   -8.37089  11.57863  1.000 34.88442 ? 7   DC  C "H2''" 1 
ATOM   217  H "H1'"  . DC  A 1 7  ? 5.31992   -7.76739  13.58036  1.000 31.46112 ? 7   DC  C "H1'"  1 
ATOM   218  H H41    . DC  A 1 7  ? 4.06009   -1.46419  13.69530  1.000 32.07028 ? 7   DC  C H41    1 
ATOM   219  H H42    . DC  A 1 7  ? 2.87038   -2.10974  14.31713  1.000 32.07028 ? 7   DC  C H42    1 
ATOM   220  H H5     . DC  A 1 7  ? 5.89030   -2.74339  12.72406  1.000 30.17477 ? 7   DC  C H5     1 
ATOM   221  H H6     . DC  A 1 7  ? 6.69658   -4.84361  12.34006  1.000 29.96415 ? 7   DC  C H6     1 
ATOM   222  P P      . DG  A 1 8  ? 5.65450   -10.22279 9.45883   1.000 39.82196 ? 8   DG  C P      1 
ATOM   223  O OP1    . DG  A 1 8  ? 5.90475   -11.66285 9.25560   1.000 42.63018 ? 8   DG  C OP1    1 
ATOM   224  O OP2    . DG  A 1 8  ? 6.01101   -9.22920  8.41808   1.000 39.64465 ? 8   DG  C OP2    1 
ATOM   225  O "O5'"  . DG  A 1 8  ? 4.11440   -10.04282 9.82089   1.000 38.78130 ? 8   DG  C "O5'"  1 
ATOM   226  C "C5'"  . DG  A 1 8  ? 3.50384   -10.89211 10.77720  1.000 37.65040 ? 8   DG  C "C5'"  1 
ATOM   227  C "C4'"  . DG  A 1 8  ? 2.03659   -10.55740 10.90887  1.000 38.95254 ? 8   DG  C "C4'"  1 
ATOM   228  O "O4'"  . DG  A 1 8  ? 1.88843   -9.22734  11.49517  1.000 37.83359 ? 8   DG  C "O4'"  1 
ATOM   229  C "C3'"  . DG  A 1 8  ? 1.27669   -10.49722 9.58605   1.000 41.32270 ? 8   DG  C "C3'"  1 
ATOM   230  O "O3'"  . DG  A 1 8  ? -0.01955  -11.01670 9.74533   1.000 44.55196 ? 8   DG  C "O3'"  1 
ATOM   231  C "C2'"  . DG  A 1 8  ? 1.25601   -9.01157  9.29691   1.000 38.24494 ? 8   DG  C "C2'"  1 
ATOM   232  C "C1'"  . DG  A 1 8  ? 1.02383   -8.47424  10.68496  1.000 38.23857 ? 8   DG  C "C1'"  1 
ATOM   233  N N9     . DG  A 1 8  ? 1.29304   -7.05416  10.82260  1.000 35.50399 ? 8   DG  C N9     1 
ATOM   234  C C8     . DG  A 1 8  ? 2.29440   -6.33028  10.21214  1.000 37.00487 ? 8   DG  C C8     1 
ATOM   235  N N7     . DG  A 1 8  ? 2.27097   -5.06037  10.50991  1.000 36.35209 ? 8   DG  C N7     1 
ATOM   236  C C5     . DG  A 1 8  ? 1.17170   -4.93308  11.34837  1.000 36.58142 ? 8   DG  C C5     1 
ATOM   237  C C6     . DG  A 1 8  ? 0.63467   -3.79063  11.96878  1.000 34.80014 ? 8   DG  C C6     1 
ATOM   238  O O6     . DG  A 1 8  ? 1.03460   -2.63005  11.90268  1.000 36.66598 ? 8   DG  C O6     1 
ATOM   239  N N1     . DG  A 1 8  ? -0.48203  -4.09305  12.72468  1.000 35.87808 ? 8   DG  C N1     1 
ATOM   240  C C2     . DG  A 1 8  ? -1.02408  -5.35321  12.85934  1.000 35.37705 ? 8   DG  C C2     1 
ATOM   241  N N2     . DG  A 1 8  ? -2.11028  -5.44852  13.62749  1.000 37.09169 ? 8   DG  C N2     1 
ATOM   242  N N3     . DG  A 1 8  ? -0.52990  -6.43670  12.29145  1.000 35.42739 ? 8   DG  C N3     1 
ATOM   243  C C4     . DG  A 1 8  ? 0.55372   -6.15195  11.53939  1.000 35.83322 ? 8   DG  C C4     1 
ATOM   244  H "H5'"  . DG  A 1 8  ? 3.93940   -10.77622 11.63613  1.000 45.18048 ? 8   DG  C "H5'"  1 
ATOM   245  H "H5''" . DG  A 1 8  ? 3.60002   -11.81559 10.49640  1.000 45.18048 ? 8   DG  C "H5''" 1 
ATOM   246  H "H4'"  . DG  A 1 8  ? 1.61590   -11.20763 11.49292  1.000 46.74305 ? 8   DG  C "H4'"  1 
ATOM   247  H "H3'"  . DG  A 1 8  ? 1.75198   -10.97832 8.89067   1.000 49.58724 ? 8   DG  C "H3'"  1 
ATOM   248  H "H2'"  . DG  A 1 8  ? 2.09783   -8.70367  8.92618   1.000 45.89393 ? 8   DG  C "H2'"  1 
ATOM   249  H "H2''" . DG  A 1 8  ? 0.53747   -8.77111  8.69129   1.000 45.89393 ? 8   DG  C "H2''" 1 
ATOM   250  H "H1'"  . DG  A 1 8  ? 0.10753   -8.61612  10.96987  1.000 45.88628 ? 8   DG  C "H1'"  1 
ATOM   251  H H8     . DG  A 1 8  ? 2.92500   -6.70987  9.64366   1.000 44.40584 ? 8   DG  C H8     1 
ATOM   252  H H1     . DG  A 1 8  ? -0.86727  -3.44722  13.14193  1.000 43.05370 ? 8   DG  C H1     1 
ATOM   253  H H21    . DG  A 1 8  ? -2.48440  -6.21309  13.75023  1.000 44.51003 ? 8   DG  C H21    1 
ATOM   254  H H22    . DG  A 1 8  ? -2.43652  -4.74540  14.00004  1.000 44.51003 ? 8   DG  C H22    1 
ATOM   255  P P      . DG  A 1 9  ? -0.57427  -12.15003 8.75487   1.000 47.51168 ? 9   DG  C P      1 
ATOM   256  O OP1    . DG  A 1 9  ? 0.10119   -13.41476 9.11472   1.000 49.65473 ? 9   DG  C OP1    1 
ATOM   257  O OP2    . DG  A 1 9  ? -0.46933  -11.63293 7.37424   1.000 48.52525 ? 9   DG  C OP2    1 
ATOM   258  O "O5'"  . DG  A 1 9  ? -2.12166  -12.26045 9.14194   1.000 46.14175 ? 9   DG  C "O5'"  1 
ATOM   259  C "C5'"  . DG  A 1 9  ? -2.48699  -12.46897 10.49367  1.000 45.88406 ? 9   DG  C "C5'"  1 
ATOM   260  C "C4'"  . DG  A 1 9  ? -3.91750  -12.03688 10.75304  1.000 45.35959 ? 9   DG  C "C4'"  1 
ATOM   261  O "O4'"  . DG  A 1 9  ? -3.94862  -10.64205 11.16931  1.000 46.06660 ? 9   DG  C "O4'"  1 
ATOM   262  C "C3'"  . DG  A 1 9  ? -4.85095  -12.10712 9.55580   1.000 43.26915 ? 9   DG  C "C3'"  1 
ATOM   263  O "O3'"  . DG  A 1 9  ? -6.14739  -12.42208 10.00561  1.000 46.07948 ? 9   DG  C "O3'"  1 
ATOM   264  C "C2'"  . DG  A 1 9  ? -4.75557  -10.70207 8.98248   1.000 42.11950 ? 9   DG  C "C2'"  1 
ATOM   265  C "C1'"  . DG  A 1 9  ? -4.72491  -9.88552  10.25580  1.000 41.45230 ? 9   DG  C "C1'"  1 
ATOM   266  N N9     . DG  A 1 9  ? -4.11310  -8.57433  10.13623  1.000 35.50064 ? 9   DG  C N9     1 
ATOM   267  C C8     . DG  A 1 9  ? -2.92166  -8.26609  9.51750   1.000 32.11751 ? 9   DG  C C8     1 
ATOM   268  N N7     . DG  A 1 9  ? -2.62265  -7.00064  9.58966   1.000 30.25644 ? 9   DG  C N7     1 
ATOM   269  C C5     . DG  A 1 9  ? -3.65369  -6.44443  10.32509  1.000 28.31131 ? 9   DG  C C5     1 
ATOM   270  C C6     . DG  A 1 9  ? -3.84751  -5.11122  10.71224  1.000 26.13039 ? 9   DG  C C6     1 
ATOM   271  O O6     . DG  A 1 9  ? -3.09798  -4.14599  10.49876  1.000 24.19011 ? 9   DG  C O6     1 
ATOM   272  N N1     . DG  A 1 9  ? -5.02207  -4.94288  11.44190  1.000 28.03965 ? 9   DG  C N1     1 
ATOM   273  C C2     . DG  A 1 9  ? -5.90725  -5.95005  11.74364  1.000 33.88939 ? 9   DG  C C2     1 
ATOM   274  N N2     . DG  A 1 9  ? -6.99390  -5.59500  12.45082  1.000 39.73808 ? 9   DG  C N2     1 
ATOM   275  N N3     . DG  A 1 9  ? -5.73898  -7.21855  11.37512  1.000 35.05115 ? 9   DG  C N3     1 
ATOM   276  C C4     . DG  A 1 9  ? -4.58600  -7.38745  10.66460  1.000 31.69270 ? 9   DG  C C4     1 
ATOM   277  H "H5'"  . DG  A 1 9  ? -1.89254  -11.95858 11.06554  1.000 55.06087 ? 9   DG  C "H5'"  1 
ATOM   278  H "H5''" . DG  A 1 9  ? -2.39668  -13.41131 10.70519  1.000 55.06087 ? 9   DG  C "H5''" 1 
ATOM   279  H "H4'"  . DG  A 1 9  ? -4.27339  -12.59017 11.46586  1.000 54.43151 ? 9   DG  C "H4'"  1 
ATOM   280  H "H3'"  . DG  A 1 9  ? -4.54787  -12.75117 8.89683   1.000 51.92298 ? 9   DG  C "H3'"  1 
ATOM   281  H "H2'"  . DG  A 1 9  ? -3.94875  -10.58128 8.45773   1.000 50.54340 ? 9   DG  C "H2'"  1 
ATOM   282  H "H2''" . DG  A 1 9  ? -5.52496  -10.48420 8.43342   1.000 50.54340 ? 9   DG  C "H2''" 1 
ATOM   283  H "H1'"  . DG  A 1 9  ? -5.63376  -9.77231  10.57529  1.000 49.74276 ? 9   DG  C "H1'"  1 
ATOM   284  H H8     . DG  A 1 9  ? -2.38619  -8.89643  9.09223   1.000 38.54101 ? 9   DG  C H8     1 
ATOM   285  H H1     . DG  A 1 9  ? -5.20666  -4.15168  11.72391  1.000 33.64757 ? 9   DG  C H1     1 
ATOM   286  H H21    . DG  A 1 9  ? -7.57988  -6.18692  12.66496  1.000 47.68570 ? 9   DG  C H21    1 
ATOM   287  H H22    . DG  A 1 9  ? -7.10313  -4.77592  12.68911  1.000 47.68570 ? 9   DG  C H22    1 
ATOM   288  P P      . DA  A 1 10 ? -7.31439  -12.77303 8.97287   1.000 48.10145 ? 10  DA  C P      1 
ATOM   289  O OP1    . DA  A 1 10 ? -8.23025  -13.68595 9.69228   1.000 51.17533 ? 10  DA  C OP1    1 
ATOM   290  O OP2    . DA  A 1 10 ? -6.69146  -13.17304 7.69143   1.000 48.39232 ? 10  DA  C OP2    1 
ATOM   291  O "O5'"  . DA  A 1 10 ? -8.04196  -11.36994 8.74911   1.000 44.65085 ? 10  DA  C "O5'"  1 
ATOM   292  C "C5'"  . DA  A 1 10 ? -8.42368  -10.60377 9.87388   1.000 40.65131 ? 10  DA  C "C5'"  1 
ATOM   293  C "C4'"  . DA  A 1 10 ? -8.75676  -9.18245  9.47748   1.000 36.86682 ? 10  DA  C "C4'"  1 
ATOM   294  O "O4'"  . DA  A 1 10 ? -7.55087  -8.44059  9.20807   1.000 34.64011 ? 10  DA  C "O4'"  1 
ATOM   295  C "C3'"  . DA  A 1 10 ? -9.60327  -9.05657  8.21993   1.000 35.58925 ? 10  DA  C "C3'"  1 
ATOM   296  O "O3'"  . DA  A 1 10 ? -10.91360 -8.68888  8.58434   1.000 38.13547 ? 10  DA  C "O3'"  1 
ATOM   297  C "C2'"  . DA  A 1 10 ? -8.89065  -7.98580  7.36812   1.000 33.45480 ? 10  DA  C "C2'"  1 
ATOM   298  C "C1'"  . DA  A 1 10 ? -7.87775  -7.38949  8.33414   1.000 32.34489 ? 10  DA  C "C1'"  1 
ATOM   299  N N9     . DA  A 1 10 ? -6.63507  -6.90433  7.73049   1.000 29.33455 ? 10  DA  C N9     1 
ATOM   300  C C8     . DA  A 1 10 ? -5.70798  -7.64121  7.04701   1.000 28.72627 ? 10  DA  C C8     1 
ATOM   301  N N7     . DA  A 1 10 ? -4.65973  -6.94785  6.66023   1.000 27.37617 ? 10  DA  C N7     1 
ATOM   302  C C5     . DA  A 1 10 ? -4.91700  -5.66416  7.12076   1.000 25.83935 ? 10  DA  C C5     1 
ATOM   303  C C6     . DA  A 1 10 ? -4.18748  -4.45468  7.03624   1.000 24.89005 ? 10  DA  C C6     1 
ATOM   304  N N6     . DA  A 1 10 ? -3.00617  -4.34560  6.42002   1.000 25.94284 ? 10  DA  C N6     1 
ATOM   305  N N1     . DA  A 1 10 ? -4.72762  -3.35793  7.60152   1.000 24.21720 ? 10  DA  C N1     1 
ATOM   306  C C2     . DA  A 1 10 ? -5.91044  -3.46573  8.21128   1.000 25.37290 ? 10  DA  C C2     1 
ATOM   307  N N3     . DA  A 1 10 ? -6.67591  -4.54032  8.37152   1.000 24.21198 ? 10  DA  C N3     1 
ATOM   308  C C4     . DA  A 1 10 ? -6.12327  -5.61875  7.78958   1.000 25.59243 ? 10  DA  C C4     1 
ATOM   309  H "H5'"  . DA  A 1 10 ? -7.69532  -10.59349 10.51441  1.000 48.78157 ? 10  DA  C "H5'"  1 
ATOM   310  H "H5''" . DA  A 1 10 ? -9.20172  -11.00997 10.28688  1.000 48.78157 ? 10  DA  C "H5''" 1 
ATOM   311  H "H4'"  . DA  A 1 10 ? -9.21396  -8.75380  10.21784  1.000 44.24018 ? 10  DA  C "H4'"  1 
ATOM   312  H "H3'"  . DA  A 1 10 ? -9.59533  -9.88837  7.72098   1.000 42.70710 ? 10  DA  C "H3'"  1 
ATOM   313  H "H2'"  . DA  A 1 10 ? -8.45002  -8.38490  6.60165   1.000 40.14576 ? 10  DA  C "H2'"  1 
ATOM   314  H "H2''" . DA  A 1 10 ? -9.51618  -7.31260  7.05763   1.000 40.14576 ? 10  DA  C "H2''" 1 
ATOM   315  H "H1'"  . DA  A 1 10 ? -8.29109  -6.64804  8.80351   1.000 38.81387 ? 10  DA  C "H1'"  1 
ATOM   316  H H8     . DA  A 1 10 ? -5.80940  -8.54892  6.87187   1.000 34.47153 ? 10  DA  C H8     1 
ATOM   317  H H61    . DA  A 1 10 ? -2.60550  -3.58524  6.38988   1.000 31.13141 ? 10  DA  C H61    1 
ATOM   318  H H62    . DA  A 1 10 ? -2.64690  -5.03579  6.05375   1.000 31.13141 ? 10  DA  C H62    1 
ATOM   319  H H2     . DA  A 1 10 ? -6.24585  -2.67825  8.57499   1.000 30.44749 ? 10  DA  C H2     1 
ATOM   320  P P      . DA  A 1 11 ? -12.06686 -8.57842  7.48348   1.000 38.46195 ? 11  DA  C P      1 
ATOM   321  O OP1    . DA  A 1 11 ? -13.36257 -8.69405  8.19772   1.000 41.01241 ? 11  DA  C OP1    1 
ATOM   322  O OP2    . DA  A 1 11 ? -11.73904 -9.48703  6.36643   1.000 38.38275 ? 11  DA  C OP2    1 
ATOM   323  O "O5'"  . DA  A 1 11 ? -11.89868 -7.09420  6.94299   1.000 32.33315 ? 11  DA  C "O5'"  1 
ATOM   324  C "C5'"  . DA  A 1 11 ? -11.98262 -6.02644  7.85148   1.000 30.57394 ? 11  DA  C "C5'"  1 
ATOM   325  C "C4'"  . DA  A 1 11 ? -11.62295 -4.72594  7.18280   1.000 26.36968 ? 11  DA  C "C4'"  1 
ATOM   326  O "O4'"  . DA  A 1 11 ? -10.20786 -4.72316  6.86686   1.000 24.84747 ? 11  DA  C "O4'"  1 
ATOM   327  C "C3'"  . DA  A 1 11 ? -12.35119 -4.45319  5.85441   1.000 25.67443 ? 11  DA  C "C3'"  1 
ATOM   328  O "O3'"  . DA  A 1 11 ? -12.84824 -3.13390  5.85672   1.000 26.95500 ? 11  DA  C "O3'"  1 
ATOM   329  C "C2'"  . DA  A 1 11 ? -11.26092 -4.65804  4.81460   1.000 24.35011 ? 11  DA  C "C2'"  1 
ATOM   330  C "C1'"  . DA  A 1 11 ? -10.05473 -4.16533  5.58432   1.000 23.56722 ? 11  DA  C "C1'"  1 
ATOM   331  N N9     . DA  A 1 11 ? -8.76265  -4.55511  5.03936   1.000 21.45027 ? 11  DA  C N9     1 
ATOM   332  C C8     . DA  A 1 11 ? -8.36695  -5.79303  4.61161   1.000 21.95461 ? 11  DA  C C8     1 
ATOM   333  N N7     . DA  A 1 11 ? -7.13475  -5.82380  4.15847   1.000 21.24703 ? 11  DA  C N7     1 
ATOM   334  C C5     . DA  A 1 11 ? -6.69830  -4.50906  4.30828   1.000 19.60077 ? 11  DA  C C5     1 
ATOM   335  C C6     . DA  A 1 11 ? -5.48923  -3.86837  4.00678   1.000 17.89745 ? 11  DA  C C6     1 
ATOM   336  N N6     . DA  A 1 11 ? -4.43844  -4.49123  3.47261   1.000 20.03082 ? 11  DA  C N6     1 
ATOM   337  N N1     . DA  A 1 11 ? -5.39906  -2.54763  4.26864   1.000 17.42814 ? 11  DA  C N1     1 
ATOM   338  C C2     . DA  A 1 11 ? -6.45116  -1.91385  4.78620   1.000 17.74666 ? 11  DA  C C2     1 
ATOM   339  N N3     . DA  A 1 11 ? -7.63714  -2.40982  5.12649   1.000 18.47765 ? 11  DA  C N3     1 
ATOM   340  C C4     . DA  A 1 11 ? -7.70175  -3.72174  4.84069   1.000 18.95926 ? 11  DA  C C4     1 
ATOM   341  H "H5'"  . DA  A 1 11 ? -11.37366 -6.18578  8.58951   1.000 36.68873 ? 11  DA  C "H5'"  1 
ATOM   342  H "H5''" . DA  A 1 11 ? -12.88776 -5.96960  8.19554   1.000 36.68873 ? 11  DA  C "H5''" 1 
ATOM   343  H "H4'"  . DA  A 1 11 ? -11.80748 -3.99429  7.79235   1.000 31.64361 ? 11  DA  C "H4'"  1 
ATOM   344  H "H3'"  . DA  A 1 11 ? -13.06517 -5.09349  5.70898   1.000 30.80932 ? 11  DA  C "H3'"  1 
ATOM   345  H "H2'"  . DA  A 1 11 ? -11.17237 -5.59085  4.56375   1.000 29.22013 ? 11  DA  C "H2'"  1 
ATOM   346  H "H2''" . DA  A 1 11 ? -11.41983 -4.13012  4.01651   1.000 29.22013 ? 11  DA  C "H2''" 1 
ATOM   347  H "H1'"  . DA  A 1 11 ? -10.06354 -3.19621  5.62451   1.000 28.28067 ? 11  DA  C "H1'"  1 
ATOM   348  H H8     . DA  A 1 11 ? -8.91820  -6.54153  4.63913   1.000 26.34554 ? 11  DA  C H8     1 
ATOM   349  H H61    . DA  A 1 11 ? -3.71951  -4.05159  3.30100   1.000 24.03698 ? 11  DA  C H61    1 
ATOM   350  H H62    . DA  A 1 11 ? -4.47955  -5.33266  3.29965   1.000 24.03698 ? 11  DA  C H62    1 
ATOM   351  H H2     . DA  A 1 11 ? -6.34095  -1.00144  4.92860   1.000 21.29599 ? 11  DA  C H2     1 
ATOM   352  P P      . DG  A 1 12 ? -13.74721 -2.56795  4.65027   1.000 24.89204 ? 12  DG  C P      1 
ATOM   353  O OP1    . DG  A 1 12 ? -14.94322 -2.01619  5.29983   1.000 26.86824 ? 12  DG  C OP1    1 
ATOM   354  O OP2    . DG  A 1 12 ? -13.89142 -3.50232  3.51177   1.000 26.06245 ? 12  DG  C OP2    1 
ATOM   355  O "O5'"  . DG  A 1 12 ? -12.88958 -1.34759  4.08040   1.000 23.49767 ? 12  DG  C "O5'"  1 
ATOM   356  C "C5'"  . DG  A 1 12 ? -12.60773 -0.24344  4.90958   1.000 22.19229 ? 12  DG  C "C5'"  1 
ATOM   357  C "C4'"  . DG  A 1 12 ? -11.75972 0.76639   4.16785   1.000 21.64362 ? 12  DG  C "C4'"  1 
ATOM   358  O "O4'"  . DG  A 1 12 ? -10.44107 0.20882   3.91895   1.000 21.39639 ? 12  DG  C "O4'"  1 
ATOM   359  C "C3'"  . DG  A 1 12 ? -12.30495 1.18654   2.80963   1.000 20.41544 ? 12  DG  C "C3'"  1 
ATOM   360  O "O3'"  . DG  A 1 12 ? -12.17465 2.56943   2.67622   1.000 22.01903 ? 12  DG  C "O3'"  1 
ATOM   361  C "C2'"  . DG  A 1 12 ? -11.44841 0.40815   1.81642   1.000 19.64491 ? 12  DG  C "C2'"  1 
ATOM   362  C "C1'"  . DG  A 1 12 ? -10.12147 0.30692   2.54308   1.000 19.39422 ? 12  DG  C "C1'"  1 
ATOM   363  N N9     . DG  A 1 12 ? -9.32440  -0.84979  2.15676   1.000 18.92862 ? 12  DG  C N9     1 
ATOM   364  C C8     . DG  A 1 12 ? -9.69519  -2.16717  2.20108   1.000 19.74654 ? 12  DG  C C8     1 
ATOM   365  N N7     . DG  A 1 12 ? -8.76418  -2.98165  1.76274   1.000 18.89927 ? 12  DG  C N7     1 
ATOM   366  C C5     . DG  A 1 12 ? -7.71450  -2.14633  1.41528   1.000 17.89461 ? 12  DG  C C5     1 
ATOM   367  C C6     . DG  A 1 12 ? -6.43252  -2.45423  0.89667   1.000 17.33968 ? 12  DG  C C6     1 
ATOM   368  O O6     . DG  A 1 12 ? -5.95607  -3.56965  0.62495   1.000 19.37589 ? 12  DG  C O6     1 
ATOM   369  N N1     . DG  A 1 12 ? -5.67595  -1.31101  0.67563   1.000 17.01095 ? 12  DG  C N1     1 
ATOM   370  C C2     . DG  A 1 12 ? -6.09544  -0.02715  0.94343   1.000 16.95071 ? 12  DG  C C2     1 
ATOM   371  N N2     . DG  A 1 12 ? -5.22725  0.95082   0.65312   1.000 17.45777 ? 12  DG  C N2     1 
ATOM   372  N N3     . DG  A 1 12 ? -7.29722  0.27411   1.42888   1.000 16.89502 ? 12  DG  C N3     1 
ATOM   373  C C4     . DG  A 1 12 ? -8.04271  -0.83236  1.65122   1.000 17.51146 ? 12  DG  C C4     1 
ATOM   374  H "H5'"  . DG  A 1 12 ? -12.13139 -0.54645  5.69837   1.000 26.63074 ? 12  DG  C "H5'"  1 
ATOM   375  H "H5''" . DG  A 1 12 ? -13.43933 0.17390   5.18374   1.000 26.63074 ? 12  DG  C "H5''" 1 
ATOM   376  H "H4'"  . DG  A 1 12 ? -11.65566 1.55841   4.71810   1.000 25.97234 ? 12  DG  C "H4'"  1 
ATOM   377  H "H3'"  . DG  A 1 12 ? -13.22919 0.91205   2.70311   1.000 24.49853 ? 12  DG  C "H3'"  1 
ATOM   378  H "H2'"  . DG  A 1 12 ? -11.82208 -0.46932  1.63944   1.000 23.57389 ? 12  DG  C "H2'"  1 
ATOM   379  H "H2''" . DG  A 1 12 ? -11.35636 0.88716   0.97798   1.000 23.57389 ? 12  DG  C "H2''" 1 
ATOM   380  H "H1'"  . DG  A 1 12 ? -9.59939  1.10947   2.38738   1.000 23.27307 ? 12  DG  C "H1'"  1 
ATOM   381  H H8     . DG  A 1 12 ? -10.52335 -2.45568  2.51063   1.000 23.69585 ? 12  DG  C H8     1 
ATOM   382  H H1     . DG  A 1 12 ? -4.88754  -1.41227  0.34738   1.000 20.41313 ? 12  DG  C H1     1 
ATOM   383  H H21    . DG  A 1 12 ? -5.44678  1.77251   0.78052   1.000 20.94932 ? 12  DG  C H21    1 
ATOM   384  H H22    . DG  A 1 12 ? -4.45036  0.75698   0.33934   1.000 20.94932 ? 12  DG  C H22    1 
ATOM   385  P P      . DT  A 1 13 ? -12.70696 3.32530   1.37013   1.000 23.94728 ? 13  DT  C P      1 
ATOM   386  O OP1    . DT  A 1 13 ? -13.14078 4.65598   1.85582   1.000 27.15161 ? 13  DT  C OP1    1 
ATOM   387  O OP2    . DT  A 1 13 ? -13.65582 2.51602   0.57534   1.000 23.75644 ? 13  DT  C OP2    1 
ATOM   388  O "O5'"  . DT  A 1 13 ? -11.39391 3.50272   0.50374   1.000 24.06041 ? 13  DT  C "O5'"  1 
ATOM   389  C "C5'"  . DT  A 1 13 ? -10.31897 4.24641   1.00877   1.000 23.16958 ? 13  DT  C "C5'"  1 
ATOM   390  C "C4'"  . DT  A 1 13 ? -9.31178  4.48366   -0.08666  1.000 21.80844 ? 13  DT  C "C4'"  1 
ATOM   391  O "O4'"  . DT  A 1 13 ? -8.61680  3.25049   -0.37647  1.000 22.54214 ? 13  DT  C "O4'"  1 
ATOM   392  C "C3'"  . DT  A 1 13 ? -9.90597  4.94698   -1.42522  1.000 22.52003 ? 13  DT  C "C3'"  1 
ATOM   393  O "O3'"  . DT  A 1 13 ? -9.14365  6.05109   -1.91743  1.000 25.18954 ? 13  DT  C "O3'"  1 
ATOM   394  C "C2'"  . DT  A 1 13 ? -9.80855  3.69565   -2.31566  1.000 22.31512 ? 13  DT  C "C2'"  1 
ATOM   395  C "C1'"  . DT  A 1 13 ? -8.53558  3.07335   -1.78576  1.000 20.74597 ? 13  DT  C "C1'"  1 
ATOM   396  N N1     . DT  A 1 13 ? -8.34062  1.62511   -1.99664  1.000 20.27193 ? 13  DT  C N1     1 
ATOM   397  C C2     . DT  A 1 13 ? -7.09182  1.17746   -2.40894  1.000 18.85458 ? 13  DT  C C2     1 
ATOM   398  O O2     . DT  A 1 13 ? -6.15845  1.92446   -2.72225  1.000 20.46388 ? 13  DT  C O2     1 
ATOM   399  N N3     . DT  A 1 13 ? -6.96848  -0.18425  -2.46769  1.000 18.19963 ? 13  DT  C N3     1 
ATOM   400  C C4     . DT  A 1 13 ? -7.91797  -1.12360  -2.13905  1.000 19.46789 ? 13  DT  C C4     1 
ATOM   401  O O4     . DT  A 1 13 ? -7.69525  -2.32965  -2.22403  1.000 19.70409 ? 13  DT  C O4     1 
ATOM   402  C C5     . DT  A 1 13 ? -9.19630  -0.59695  -1.70323  1.000 20.36565 ? 13  DT  C C5     1 
ATOM   403  C C7     . DT  A 1 13 ? -10.29978 -1.53726  -1.34997  1.000 21.62802 ? 13  DT  C C7     1 
ATOM   404  C C6     . DT  A 1 13 ? -9.34101  0.73551   -1.62551  1.000 19.24167 ? 13  DT  C C6     1 
ATOM   405  H "H5'"  . DT  A 1 13 ? -9.89998  3.75954   1.73561   1.000 27.80349 ? 13  DT  C "H5'"  1 
ATOM   406  H "H5''" . DT  A 1 13 ? -10.64160 5.09773   1.34355   1.000 27.80349 ? 13  DT  C "H5''" 1 
ATOM   407  H "H4'"  . DT  A 1 13 ? -8.66751  5.14315   0.21481   1.000 26.17013 ? 13  DT  C "H4'"  1 
ATOM   408  H "H3'"  . DT  A 1 13 ? -10.84062 5.18912   -1.33197  1.000 27.02404 ? 13  DT  C "H3'"  1 
ATOM   409  H "H2'"  . DT  A 1 13 ? -10.57204 3.10930   -2.19659  1.000 26.77814 ? 13  DT  C "H2'"  1 
ATOM   410  H "H2''" . DT  A 1 13 ? -9.73175  3.92745   -3.25442  1.000 26.77814 ? 13  DT  C "H2''" 1 
ATOM   411  H "H1'"  . DT  A 1 13 ? -7.79365  3.53727   -2.20436  1.000 24.89516 ? 13  DT  C "H1'"  1 
ATOM   412  H H3     . DT  A 1 13 ? -6.21139  -0.48699  -2.74112  1.000 21.83955 ? 13  DT  C H3     1 
ATOM   413  H H71    . DT  A 1 13 ? -10.62019 -1.32759  -0.45875  1.000 25.95363 ? 13  DT  C H71    1 
ATOM   414  H H72    . DT  A 1 13 ? -11.01923 -1.43554  -1.99258  1.000 25.95363 ? 13  DT  C H72    1 
ATOM   415  H H73    . DT  A 1 13 ? -9.96053  -2.44568  -1.37430  1.000 25.95363 ? 13  DT  C H73    1 
ATOM   416  H H6     . DT  A 1 13 ? -10.14589 1.07785   -1.30950  1.000 23.09000 ? 13  DT  C H6     1 
ATOM   417  P P      . DG  A 1 14 ? -9.61413  6.86224   -3.22296  1.000 26.78092 ? 14  DG  C P      1 
ATOM   418  O OP1    . DG  A 1 14 ? -9.29746  8.28241   -2.94318  1.000 29.45977 ? 14  DG  C OP1    1 
ATOM   419  O OP2    . DG  A 1 14 ? -11.00506 6.47937   -3.54789  1.000 27.36903 ? 14  DG  C OP2    1 
ATOM   420  O "O5'"  . DG  A 1 14 ? -8.67404  6.30489   -4.38867  1.000 30.24144 ? 14  DG  C "O5'"  1 
ATOM   421  C "C5'"  . DG  A 1 14 ? -7.28872  6.21256   -4.17417  1.000 31.34260 ? 14  DG  C "C5'"  1 
ATOM   422  C "C4'"  . DG  A 1 14 ? -6.53926  5.65177   -5.39257  1.000 28.92301 ? 14  DG  C "C4'"  1 
ATOM   423  O "O4'"  . DG  A 1 14 ? -6.44210  4.21436   -5.32250  1.000 28.57065 ? 14  DG  C "O4'"  1 
ATOM   424  C "C3'"  . DG  A 1 14 ? -7.12553  5.95428   -6.77506  1.000 28.77747 ? 14  DG  C "C3'"  1 
ATOM   425  O "O3'"  . DG  A 1 14 ? -6.13589  6.65097   -7.49996  1.000 30.36247 ? 14  DG  C "O3'"  1 
ATOM   426  C "C2'"  . DG  A 1 14 ? -7.45939  4.56327   -7.37489  1.000 27.20798 ? 14  DG  C "C2'"  1 
ATOM   427  C "C1'"  . DG  A 1 14 ? -6.49397  3.66673   -6.63777  1.000 24.95177 ? 14  DG  C "C1'"  1 
ATOM   428  N N9     . DG  A 1 14 ? -6.84697  2.25575   -6.46800  1.000 21.90255 ? 14  DG  C N9     1 
ATOM   429  C C8     . DG  A 1 14 ? -5.97826  1.19774   -6.53429  1.000 21.58412 ? 14  DG  C C8     1 
ATOM   430  N N7     . DG  A 1 14 ? -6.51578  0.05245   -6.23686  1.000 19.98031 ? 14  DG  C N7     1 
ATOM   431  C C5     . DG  A 1 14 ? -7.82526  0.37004   -5.90371  1.000 19.61231 ? 14  DG  C C5     1 
ATOM   432  C C6     . DG  A 1 14 ? -8.85796  -0.46163  -5.46754  1.000 20.09146 ? 14  DG  C C6     1 
ATOM   433  O O6     . DG  A 1 14 ? -8.82134  -1.68671  -5.29679  1.000 20.25957 ? 14  DG  C O6     1 
ATOM   434  N N1     . DG  A 1 14 ? -10.03965 0.25592   -5.25817  1.000 21.74496 ? 14  DG  C N1     1 
ATOM   435  C C2     . DG  A 1 14 ? -10.17006 1.61470   -5.41720  1.000 21.69465 ? 14  DG  C C2     1 
ATOM   436  N N2     . DG  A 1 14 ? -11.39595 2.13357   -5.17252  1.000 23.53234 ? 14  DG  C N2     1 
ATOM   437  N N3     . DG  A 1 14 ? -9.18951  2.41276   -5.79431  1.000 22.49845 ? 14  DG  C N3     1 
ATOM   438  C C4     . DG  A 1 14 ? -8.04814  1.72787   -6.02366  1.000 20.91877 ? 14  DG  C C4     1 
ATOM   439  H "H5'"  . DG  A 1 14 ? -7.12810  5.63197   -3.41389  1.000 37.61112 ? 14  DG  C "H5'"  1 
ATOM   440  H "H5''" . DG  A 1 14 ? -6.94363  7.09688   -3.97468  1.000 37.61112 ? 14  DG  C "H5''" 1 
ATOM   441  H "H4'"  . DG  A 1 14 ? -5.64424  6.02432   -5.36014  1.000 34.70761 ? 14  DG  C "H4'"  1 
ATOM   442  H "H3'"  . DG  A 1 14 ? -7.95724  6.45003   -6.71687  1.000 34.53296 ? 14  DG  C "H3'"  1 
ATOM   443  H "H2'"  . DG  A 1 14 ? -8.38013  4.31313   -7.20007  1.000 32.64957 ? 14  DG  C "H2'"  1 
ATOM   444  H "H2''" . DG  A 1 14 ? -7.30279  4.54264   -8.33194  1.000 32.64957 ? 14  DG  C "H2''" 1 
ATOM   445  H "H1'"  . DG  A 1 14 ? -5.65432  3.69870   -7.12240  1.000 29.94213 ? 14  DG  C "H1'"  1 
ATOM   446  H H8     . DG  A 1 14 ? -5.08375  1.29106   -6.77104  1.000 25.90095 ? 14  DG  C H8     1 
ATOM   447  H H1     . DG  A 1 14 ? -10.73560 -0.18523  -5.01192  1.000 26.09395 ? 14  DG  C H1     1 
ATOM   448  H H21    . DG  A 1 14 ? -11.53139 2.97798   -5.26318  1.000 28.23880 ? 14  DG  C H21    1 
ATOM   449  H H22    . DG  A 1 14 ? -12.03943 1.61884   -4.92638  1.000 28.23880 ? 14  DG  C H22    1 
ATOM   450  P P      . DG  A 1 15 ? -6.43115  7.32361   -8.92654  1.000 34.13076 ? 15  DG  C P      1 
ATOM   451  O OP1    . DG  A 1 15 ? -5.44709  8.41201   -9.06146  1.000 36.75491 ? 15  DG  C OP1    1 
ATOM   452  O OP2    . DG  A 1 15 ? -7.88597  7.57702   -9.08548  1.000 33.68428 ? 15  DG  C OP2    1 
ATOM   453  O "O5'"  . DG  A 1 15 ? -6.06321  6.17425   -9.94727  1.000 31.36822 ? 15  DG  C "O5'"  1 
ATOM   454  C "C5'"  . DG  A 1 15 ? -4.75840  5.66628   -9.97446  1.000 30.12631 ? 15  DG  C "C5'"  1 
ATOM   455  C "C4'"  . DG  A 1 15 ? -4.71062  4.43596   -10.82968 1.000 27.84776 ? 15  DG  C "C4'"  1 
ATOM   456  O "O4'"  . DG  A 1 15 ? -5.37798  3.34329   -10.13641 1.000 24.94627 ? 15  DG  C "O4'"  1 
ATOM   457  C "C3'"  . DG  A 1 15 ? -5.42727  4.57264   -12.17754 1.000 26.76022 ? 15  DG  C "C3'"  1 
ATOM   458  O "O3'"  . DG  A 1 15 ? -4.59049  4.10650   -13.22418 1.000 28.70536 ? 15  DG  C "O3'"  1 
ATOM   459  C "C2'"  . DG  A 1 15 ? -6.66721  3.70136   -12.01039 1.000 25.24779 ? 15  DG  C "C2'"  1 
ATOM   460  C "C1'"  . DG  A 1 15 ? -6.14575  2.64051   -11.07838 1.000 23.37799 ? 15  DG  C "C1'"  1 
ATOM   461  N N9     . DG  A 1 15 ? -7.17520  1.85704   -10.40803 1.000 20.68013 ? 15  DG  C N9     1 
ATOM   462  C C8     . DG  A 1 15 ? -8.41362  2.26616   -9.97796  1.000 20.67617 ? 15  DG  C C8     1 
ATOM   463  N N7     . DG  A 1 15 ? -9.10972  1.30478   -9.43351  1.000 19.44397 ? 15  DG  C N7     1 
ATOM   464  C C5     . DG  A 1 15 ? -8.27676  0.19852   -9.50971  1.000 18.96576 ? 15  DG  C C5     1 
ATOM   465  C C6     . DG  A 1 15 ? -8.47584  -1.12915  -9.08200  1.000 19.34243 ? 15  DG  C C6     1 
ATOM   466  O O6     . DG  A 1 15 ? -9.46986  -1.62613  -8.53641  1.000 19.45086 ? 15  DG  C O6     1 
ATOM   467  N N1     . DG  A 1 15 ? -7.37167  -1.92659  -9.36029  1.000 18.34918 ? 15  DG  C N1     1 
ATOM   468  C C2     . DG  A 1 15 ? -6.22256  -1.49669  -9.97363  1.000 18.95670 ? 15  DG  C C2     1 
ATOM   469  N N2     . DG  A 1 15 ? -5.26461  -2.41078  -10.14207 1.000 20.05414 ? 15  DG  C N2     1 
ATOM   470  N N3     . DG  A 1 15 ? -6.01642  -0.25464  -10.36768 1.000 18.83277 ? 15  DG  C N3     1 
ATOM   471  C C4     . DG  A 1 15 ? -7.08581  0.53159   -10.10794 1.000 19.32147 ? 15  DG  C C4     1 
ATOM   472  H "H5'"  . DG  A 1 15 ? -4.47803  5.44501   -9.07261  1.000 36.15158 ? 15  DG  C "H5'"  1 
ATOM   473  H "H5''" . DG  A 1 15 ? -4.15747  6.33609   -10.33660 1.000 36.15158 ? 15  DG  C "H5''" 1 
ATOM   474  H "H4'"  . DG  A 1 15 ? -3.78651  4.18633   -10.98651 1.000 33.41731 ? 15  DG  C "H4'"  1 
ATOM   475  H "H3'"  . DG  A 1 15 ? -5.68801  5.49491   -12.32698 1.000 32.11226 ? 15  DG  C "H3'"  1 
ATOM   476  H "H2'"  . DG  A 1 15 ? -7.40249  4.19576   -11.61563 1.000 30.29735 ? 15  DG  C "H2'"  1 
ATOM   477  H "H2''" . DG  A 1 15 ? -6.95768  3.32483   -12.85582 1.000 30.29735 ? 15  DG  C "H2''" 1 
ATOM   478  H "H1'"  . DG  A 1 15 ? -5.58364  2.01336   -11.55965 1.000 28.05358 ? 15  DG  C "H1'"  1 
ATOM   479  H H8     . DG  A 1 15 ? -8.72455  3.13827   -10.06548 1.000 24.81141 ? 15  DG  C H8     1 
ATOM   480  H H1     . DG  A 1 15 ? -7.41222  -2.75416  -9.12987  1.000 22.01902 ? 15  DG  C H1     1 
ATOM   481  H H21    . DG  A 1 15 ? -4.51763  -2.18881  -10.50587 1.000 24.06497 ? 15  DG  C H21    1 
ATOM   482  H H22    . DG  A 1 15 ? -5.39437  -3.22170  -9.88679  1.000 24.06497 ? 15  DG  C H22    1 
ATOM   483  P P      . DG  A 1 16 ? -4.88257  4.50896   -14.74145 1.000 34.03312 ? 16  DG  C P      1 
ATOM   484  O OP1    . DG  A 1 16 ? -3.63379  4.22506   -15.48860 1.000 36.71850 ? 16  DG  C OP1    1 
ATOM   485  O OP2    . DG  A 1 16 ? -5.48475  5.85666   -14.77485 1.000 35.95436 ? 16  DG  C OP2    1 
ATOM   486  O "O5'"  . DG  A 1 16 ? -6.01083  3.47631   -15.21087 1.000 35.29893 ? 16  DG  C "O5'"  1 
ATOM   487  C "C5'"  . DG  A 1 16 ? -5.66667  2.31933   -15.98023 1.000 33.71622 ? 16  DG  C "C5'"  1 
ATOM   488  C "C4'"  . DG  A 1 16 ? -5.04837  1.22618   -15.11806 1.000 30.69841 ? 16  DG  C "C4'"  1 
ATOM   489  O "O4'"  . DG  A 1 16 ? -5.90334  0.96201   -13.96864 1.000 26.86409 ? 16  DG  C "O4'"  1 
ATOM   490  C "C3'"  . DG  A 1 16 ? -4.88547  -0.11925  -15.82050 1.000 32.78262 ? 16  DG  C "C3'"  1 
ATOM   491  O "O3'"  . DG  A 1 16 ? -3.68230  -0.74635  -15.42004 1.000 35.20601 ? 16  DG  C "O3'"  1 
ATOM   492  C "C2'"  . DG  A 1 16 ? -6.11767  -0.89255  -15.37173 1.000 28.88308 ? 16  DG  C "C2'"  1 
ATOM   493  C "C1'"  . DG  A 1 16 ? -6.27458  -0.40124  -13.94911 1.000 25.40788 ? 16  DG  C "C1'"  1 
ATOM   494  N N9     . DG  A 1 16 ? -7.61671  -0.51118  -13.39813 1.000 21.15813 ? 16  DG  C N9     1 
ATOM   495  C C8     . DG  A 1 16 ? -8.55177  0.48569   -13.25879 1.000 20.38004 ? 16  DG  C C8     1 
ATOM   496  N N7     . DG  A 1 16 ? -9.65148  0.08491   -12.69836 1.000 18.83147 ? 16  DG  C N7     1 
ATOM   497  C C5     . DG  A 1 16 ? -9.43638  -1.26627  -12.46369 1.000 18.22527 ? 16  DG  C C5     1 
ATOM   498  C C6     . DG  A 1 16 ? -10.26004 -2.22893  -11.84879 1.000 17.92185 ? 16  DG  C C6     1 
ATOM   499  O O6     . DG  A 1 16 ? -11.40998 -2.08799  -11.41680 1.000 19.30063 ? 16  DG  C O6     1 
ATOM   500  N N1     . DG  A 1 16 ? -9.62348  -3.47463  -11.76630 1.000 17.36745 ? 16  DG  C N1     1 
ATOM   501  C C2     . DG  A 1 16 ? -8.37370  -3.74677  -12.23902 1.000 18.90716 ? 16  DG  C C2     1 
ATOM   502  N N2     . DG  A 1 16 ? -7.96016  -5.01571  -12.10646 1.000 19.28276 ? 16  DG  C N2     1 
ATOM   503  N N3     . DG  A 1 16 ? -7.59003  -2.84639  -12.80916 1.000 19.61244 ? 16  DG  C N3     1 
ATOM   504  C C4     . DG  A 1 16 ? -8.17115  -1.63207  -12.86160 1.000 18.62336 ? 16  DG  C C4     1 
ATOM   505  H "H5'"  . DG  A 1 16 ? -5.03218  2.57525   -16.66785 1.000 40.45946 ? 16  DG  C "H5'"  1 
ATOM   506  H "H5''" . DG  A 1 16 ? -6.46766  1.97216   -16.40305 1.000 40.45946 ? 16  DG  C "H5''" 1 
ATOM   507  H "H4'"  . DG  A 1 16 ? -4.18417  1.52810   -14.79729 1.000 36.83809 ? 16  DG  C "H4'"  1 
ATOM   508  H "H3'"  . DG  A 1 16 ? -4.89846  -0.00084  -16.78316 1.000 39.33915 ? 16  DG  C "H3'"  1 
ATOM   509  H "HO3'" . DG  A 1 16 ? -3.70373  -1.50489  -15.05982 1.000 42.24721 ? 16  DG  C "HO3'" 1 
ATOM   510  H "H2'"  . DG  A 1 16 ? -6.89282  -0.67426  -15.91247 1.000 34.65970 ? 16  DG  C "H2'"  1 
ATOM   511  H "H2''" . DG  A 1 16 ? -5.96952  -1.85062  -15.40438 1.000 34.65970 ? 16  DG  C "H2''" 1 
ATOM   512  H "H1'"  . DG  A 1 16 ? -5.67458  -0.90528  -13.37741 1.000 30.48946 ? 16  DG  C "H1'"  1 
ATOM   513  H H8     . DG  A 1 16 ? -8.41057  1.36132   -13.53851 1.000 24.45605 ? 16  DG  C H8     1 
ATOM   514  H H1     . DG  A 1 16 ? -10.05384 -4.11639  -11.38876 1.000 20.84094 ? 16  DG  C H1     1 
ATOM   515  H H21    . DG  A 1 16 ? -7.18278  -5.24675  -12.39264 1.000 23.13931 ? 16  DG  C H21    1 
ATOM   516  H H22    . DG  A 1 16 ? -8.47236  -5.59834  -11.73527 1.000 23.13931 ? 16  DG  C H22    1 
ATOM   517  O "O5'"  . DT  B 2 1  ? -17.56319 -9.18470  -10.41964 1.000 45.51767 ? 17  DT  D "O5'"  1 
ATOM   518  C "C5'"  . DT  B 2 1  ? -17.52258 -10.06640 -11.54435 1.000 41.05639 ? 17  DT  D "C5'"  1 
ATOM   519  C "C4'"  . DT  B 2 1  ? -16.10046 -10.56826 -11.82937 1.000 34.27993 ? 17  DT  D "C4'"  1 
ATOM   520  O "O4'"  . DT  B 2 1  ? -15.32821 -9.54466  -12.50654 1.000 29.52654 ? 17  DT  D "O4'"  1 
ATOM   521  C "C3'"  . DT  B 2 1  ? -15.26128 -10.96395 -10.62433 1.000 31.04426 ? 17  DT  D "C3'"  1 
ATOM   522  O "O3'"  . DT  B 2 1  ? -14.44632 -12.07065 -10.98804 1.000 28.47875 ? 17  DT  D "O3'"  1 
ATOM   523  C "C2'"  . DT  B 2 1  ? -14.43949 -9.70441  -10.31381 1.000 27.80249 ? 17  DT  D "C2'"  1 
ATOM   524  C "C1'"  . DT  B 2 1  ? -14.23497 -9.10005  -11.69309 1.000 26.47578 ? 17  DT  D "C1'"  1 
ATOM   525  N N1     . DT  B 2 1  ? -14.26825 -7.64078  -11.78438 1.000 22.98946 ? 17  DT  D N1     1 
ATOM   526  C C2     . DT  B 2 1  ? -13.31671 -7.00840  -12.54826 1.000 22.06425 ? 17  DT  D C2     1 
ATOM   527  O O2     . DT  B 2 1  ? -12.35875 -7.58619  -13.03923 1.000 23.70206 ? 17  DT  D O2     1 
ATOM   528  N N3     . DT  B 2 1  ? -13.48881 -5.66352  -12.67085 1.000 20.43067 ? 17  DT  D N3     1 
ATOM   529  C C4     . DT  B 2 1  ? -14.52922 -4.90197  -12.15801 1.000 21.36607 ? 17  DT  D C4     1 
ATOM   530  O O4     . DT  B 2 1  ? -14.60883 -3.68534  -12.34250 1.000 22.79743 ? 17  DT  D O4     1 
ATOM   531  C C5     . DT  B 2 1  ? -15.51390 -5.63411  -11.39959 1.000 24.29505 ? 17  DT  D C5     1 
ATOM   532  C C7     . DT  B 2 1  ? -16.68845 -4.91877  -10.78667 1.000 26.39811 ? 17  DT  D C7     1 
ATOM   533  C C6     . DT  B 2 1  ? -15.34883 -6.95844  -11.27238 1.000 24.58362 ? 17  DT  D C6     1 
ATOM   534  H "H5'"  . DT  B 2 1  ? -17.85324 -9.59604  -12.32558 1.000 49.26767 ? 17  DT  D "H5'"  1 
ATOM   535  H "H5''" . DT  B 2 1  ? -18.09629 -10.82846 -11.36823 1.000 49.26767 ? 17  DT  D "H5''" 1 
ATOM   536  H "H4'"  . DT  B 2 1  ? -16.18290 -11.34046 -12.41059 1.000 41.13591 ? 17  DT  D "H4'"  1 
ATOM   537  H "H3'"  . DT  B 2 1  ? -15.82004 -11.16669 -9.85779  1.000 37.25311 ? 17  DT  D "H3'"  1 
ATOM   538  H "H2'"  . DT  B 2 1  ? -14.92636 -9.09980  -9.73218  1.000 33.36299 ? 17  DT  D "H2'"  1 
ATOM   539  H "H2''" . DT  B 2 1  ? -13.59254 -9.92922  -9.89782  1.000 33.36299 ? 17  DT  D "H2''" 1 
ATOM   540  H "H1'"  . DT  B 2 1  ? -13.37638 -9.42834  -12.00284 1.000 31.77093 ? 17  DT  D "H1'"  1 
ATOM   541  H H3     . DT  B 2 1  ? -12.88665 -5.23940  -13.11485 1.000 24.51681 ? 17  DT  D H3     1 
ATOM   542  H H71    . DT  B 2 1  ? -17.50770 -5.34506  -11.08332 1.000 31.67773 ? 17  DT  D H71    1 
ATOM   543  H H72    . DT  B 2 1  ? -16.62013 -4.96981  -9.82042  1.000 31.67773 ? 17  DT  D H72    1 
ATOM   544  H H73    . DT  B 2 1  ? -16.67659 -3.99133  -11.07058 1.000 31.67773 ? 17  DT  D H73    1 
ATOM   545  H H6     . DT  B 2 1  ? -15.99824 -7.44148  -10.81429 1.000 29.50035 ? 17  DT  D H6     1 
ATOM   546  H "HO5'" . DT  B 2 1  ? -18.09029 -8.53092  -10.41793 1.000 54.62121 ? 17  DT  D "HO5'" 1 
ATOM   547  P P      . DC  B 2 2  ? -13.71762 -12.97552 -9.88347  1.000 27.30373 ? 18  DC  D P      1 
ATOM   548  O OP1    . DC  B 2 2  ? -13.38672 -14.24149 -10.56465 1.000 26.51854 ? 18  DC  D OP1    1 
ATOM   549  O OP2    . DC  B 2 2  ? -14.52949 -13.03035 -8.64493  1.000 31.84993 ? 18  DC  D OP2    1 
ATOM   550  O "O5'"  . DC  B 2 2  ? -12.36626 -12.19046 -9.59440  1.000 24.19672 ? 18  DC  D "O5'"  1 
ATOM   551  C "C5'"  . DC  B 2 2  ? -11.37703 -12.13154 -10.58801 1.000 23.90475 ? 18  DC  D "C5'"  1 
ATOM   552  C "C4'"  . DC  B 2 2  ? -10.33178 -11.11671 -10.21883 1.000 23.31333 ? 18  DC  D "C4'"  1 
ATOM   553  O "O4'"  . DC  B 2 2  ? -10.81908 -9.77791  -10.50303 1.000 20.99785 ? 18  DC  D "O4'"  1 
ATOM   554  C "C3'"  . DC  B 2 2  ? -9.95085  -11.09751 -8.72505  1.000 23.11872 ? 18  DC  D "C3'"  1 
ATOM   555  O "O3'"  . DC  B 2 2  ? -8.57062  -10.99817 -8.59003  1.000 25.13528 ? 18  DC  D "O3'"  1 
ATOM   556  C "C2'"  . DC  B 2 2  ? -10.63372 -9.83413  -8.22585  1.000 22.99383 ? 18  DC  D "C2'"  1 
ATOM   557  C "C1'"  . DC  B 2 2  ? -10.40698 -8.97470  -9.43786  1.000 21.92699 ? 18  DC  D "C1'"  1 
ATOM   558  N N1     . DC  B 2 2  ? -11.09282 -7.68107  -9.47257  1.000 20.65889 ? 18  DC  D N1     1 
ATOM   559  C C2     . DC  B 2 2  ? -10.55694 -6.69831  -10.29886 1.000 19.34153 ? 18  DC  D C2     1 
ATOM   560  O O2     . DC  B 2 2  ? -9.57960  -6.98323  -10.99881 1.000 19.84950 ? 18  DC  D O2     1 
ATOM   561  N N3     . DC  B 2 2  ? -11.12320 -5.48030  -10.32922 1.000 19.24455 ? 18  DC  D N3     1 
ATOM   562  C C4     . DC  B 2 2  ? -12.17847 -5.22180  -9.57168  1.000 19.97883 ? 18  DC  D C4     1 
ATOM   563  N N4     . DC  B 2 2  ? -12.69286 -3.99589  -9.63662  1.000 20.68057 ? 18  DC  D N4     1 
ATOM   564  C C5     . DC  B 2 2  ? -12.74268 -6.20644  -8.69996  1.000 21.57025 ? 18  DC  D C5     1 
ATOM   565  C C6     . DC  B 2 2  ? -12.16593 -7.41375  -8.67629  1.000 23.51853 ? 18  DC  D C6     1 
ATOM   566  H "H5'"  . DC  B 2 2  ? -11.78327 -11.88318 -11.43311 1.000 28.68570 ? 18  DC  D "H5'"  1 
ATOM   567  H "H5''" . DC  B 2 2  ? -10.96151 -13.00304 -10.68139 1.000 28.68570 ? 18  DC  D "H5''" 1 
ATOM   568  H "H4'"  . DC  B 2 2  ? -9.53845  -11.27938 -10.75275 1.000 27.97599 ? 18  DC  D "H4'"  1 
ATOM   569  H "H3'"  . DC  B 2 2  ? -10.29519 -11.88452 -8.27454  1.000 27.74247 ? 18  DC  D "H3'"  1 
ATOM   570  H "H2'"  . DC  B 2 2  ? -11.57622 -9.97210  -8.04266  1.000 27.59260 ? 18  DC  D "H2'"  1 
ATOM   571  H "H2''" . DC  B 2 2  ? -10.20740 -9.47321  -7.43283  1.000 27.59260 ? 18  DC  D "H2''" 1 
ATOM   572  H "H1'"  . DC  B 2 2  ? -9.46385  -8.75999  -9.51063  1.000 26.31239 ? 18  DC  D "H1'"  1 
ATOM   573  H H41    . DC  B 2 2  ? -13.37823 -3.79130  -9.15911  1.000 24.81668 ? 18  DC  D H41    1 
ATOM   574  H H42    . DC  B 2 2  ? -12.33985 -3.40840  -10.15608 1.000 24.81668 ? 18  DC  D H42    1 
ATOM   575  H H5     . DC  B 2 2  ? -13.48231 -6.01454  -8.16985  1.000 25.88430 ? 18  DC  D H5     1 
ATOM   576  H H6     . DC  B 2 2  ? -12.49947 -8.07434  -8.11302  1.000 28.22223 ? 18  DC  D H6     1 
ATOM   577  P P      . DC  B 2 3  ? -7.70997  -12.01079 -7.70125  1.000 26.16477 ? 19  DC  D P      1 
ATOM   578  O OP1    . DC  B 2 3  ? -7.82545  -13.37898 -8.28183  1.000 27.31315 ? 19  DC  D OP1    1 
ATOM   579  O OP2    . DC  B 2 3  ? -8.04493  -11.82276 -6.28448  1.000 28.80942 ? 19  DC  D OP2    1 
ATOM   580  O "O5'"  . DC  B 2 3  ? -6.26052  -11.42950 -7.95889  1.000 25.05180 ? 19  DC  D "O5'"  1 
ATOM   581  C "C5'"  . DC  B 2 3  ? -5.77224  -11.34416 -9.28299  1.000 25.88905 ? 19  DC  D "C5'"  1 
ATOM   582  C "C4'"  . DC  B 2 3  ? -5.11991  -9.99754  -9.55813  1.000 24.62517 ? 19  DC  D "C4'"  1 
ATOM   583  O "O4'"  . DC  B 2 3  ? -6.12709  -8.95755  -9.56963  1.000 23.26140 ? 19  DC  D "O4'"  1 
ATOM   584  C "C3'"  . DC  B 2 3  ? -4.06891  -9.55141  -8.53450  1.000 26.61133 ? 19  DC  D "C3'"  1 
ATOM   585  O "O3'"  . DC  B 2 3  ? -2.83243  -9.28090  -9.19480  1.000 29.04032 ? 19  DC  D "O3'"  1 
ATOM   586  C "C2'"  . DC  B 2 3  ? -4.66978  -8.29854  -7.91804  1.000 25.39193 ? 19  DC  D "C2'"  1 
ATOM   587  C "C1'"  . DC  B 2 3  ? -5.55381  -7.79825  -9.04289  1.000 23.71992 ? 19  DC  D "C1'"  1 
ATOM   588  N N1     . DC  B 2 3  ? -6.63232  -6.87238  -8.62030  1.000 21.03740 ? 19  DC  D N1     1 
ATOM   589  C C2     . DC  B 2 3  ? -6.59197  -5.53356  -9.01066  1.000 20.76449 ? 19  DC  D C2     1 
ATOM   590  O O2     . DC  B 2 3  ? -5.66393  -5.13776  -9.73477  1.000 21.61891 ? 19  DC  D O2     1 
ATOM   591  N N3     . DC  B 2 3  ? -7.59536  -4.70242  -8.60812  1.000 19.75418 ? 19  DC  D N3     1 
ATOM   592  C C4     . DC  B 2 3  ? -8.56098  -5.15766  -7.81823  1.000 19.89538 ? 19  DC  D C4     1 
ATOM   593  N N4     . DC  B 2 3  ? -9.52292  -4.29845  -7.43905  1.000 20.81623 ? 19  DC  D N4     1 
ATOM   594  C C5     . DC  B 2 3  ? -8.60854  -6.51635  -7.40567  1.000 19.52445 ? 19  DC  D C5     1 
ATOM   595  C C6     . DC  B 2 3  ? -7.63093  -7.32678  -7.81025  1.000 20.30577 ? 19  DC  D C6     1 
ATOM   596  H "H5'"  . DC  B 2 3  ? -6.50973  -11.46998 -9.90039  1.000 31.06686 ? 19  DC  D "H5'"  1 
ATOM   597  H "H5''" . DC  B 2 3  ? -5.11853  -12.04667 -9.42454  1.000 31.06686 ? 19  DC  D "H5''" 1 
ATOM   598  H "H4'"  . DC  B 2 3  ? -4.70106  -10.03158 -10.43237 1.000 29.55021 ? 19  DC  D "H4'"  1 
ATOM   599  H "H3'"  . DC  B 2 3  ? -3.95924  -10.23036 -7.85048  1.000 31.93359 ? 19  DC  D "H3'"  1 
ATOM   600  H "H2'"  . DC  B 2 3  ? -5.18708  -8.50553  -7.12403  1.000 30.47031 ? 19  DC  D "H2'"  1 
ATOM   601  H "H2''" . DC  B 2 3  ? -3.98486  -7.65105  -7.68882  1.000 30.47031 ? 19  DC  D "H2''" 1 
ATOM   602  H "H1'"  . DC  B 2 3  ? -5.02060  -7.34008  -9.71123  1.000 28.46390 ? 19  DC  D "H1'"  1 
ATOM   603  H H41    . DC  B 2 3  ? -10.16079 -4.56543  -6.92773  1.000 24.97947 ? 19  DC  D H41    1 
ATOM   604  H H42    . DC  B 2 3  ? -9.50040  -3.48183  -7.70779  1.000 24.97947 ? 19  DC  D H42    1 
ATOM   605  H H5     . DC  B 2 3  ? -9.30061  -6.83056  -6.86975  1.000 23.42934 ? 19  DC  D H5     1 
ATOM   606  H H6     . DC  B 2 3  ? -7.62971  -8.21544  -7.53608  1.000 24.36692 ? 19  DC  D H6     1 
ATOM   607  P P      . DC  B 2 4  ? -1.56254  -8.64179  -8.42224  1.000 32.35764 ? 20  DC  D P      1 
ATOM   608  O OP1    . DC  B 2 4  ? -0.36830  -9.09049  -9.17808  1.000 38.24773 ? 20  DC  D OP1    1 
ATOM   609  O OP2    . DC  B 2 4  ? -1.64042  -8.88500  -6.96177  1.000 33.28551 ? 20  DC  D OP2    1 
ATOM   610  O "O5'"  . DC  B 2 4  ? -1.72333  -7.07281  -8.62582  1.000 30.66500 ? 20  DC  D "O5'"  1 
ATOM   611  C "C5'"  . DC  B 2 4  ? -1.61640  -6.52794  -9.91231  1.000 29.40205 ? 20  DC  D "C5'"  1 
ATOM   612  C "C4'"  . DC  B 2 4  ? -1.33155  -5.05091  -9.83696  1.000 25.55577 ? 20  DC  D "C4'"  1 
ATOM   613  O "O4'"  . DC  B 2 4  ? -2.48622  -4.35340  -9.31532  1.000 23.89283 ? 20  DC  D "O4'"  1 
ATOM   614  C "C3'"  . DC  B 2 4  ? -0.17213  -4.67039  -8.92919  1.000 23.87741 ? 20  DC  D "C3'"  1 
ATOM   615  O "O3'"  . DC  B 2 4  ? 0.61432   -3.68396  -9.58322  1.000 23.76594 ? 20  DC  D "O3'"  1 
ATOM   616  C "C2'"  . DC  B 2 4  ? -0.85955  -4.16103  -7.64657  1.000 22.31529 ? 20  DC  D "C2'"  1 
ATOM   617  C "C1'"  . DC  B 2 4  ? -2.12029  -3.55171  -8.19670  1.000 22.01059 ? 20  DC  D "C1'"  1 
ATOM   618  N N1     . DC  B 2 4  ? -3.30874  -3.56829  -7.31913  1.000 20.39317 ? 20  DC  D N1     1 
ATOM   619  C C2     . DC  B 2 4  ? -4.04460  -2.39543  -7.13456  1.000 21.13067 ? 20  DC  D C2     1 
ATOM   620  O O2     . DC  B 2 4  ? -3.60310  -1.32691  -7.58129  1.000 22.45419 ? 20  DC  D O2     1 
ATOM   621  N N3     . DC  B 2 4  ? -5.21157  -2.45629  -6.45100  1.000 19.73360 ? 20  DC  D N3     1 
ATOM   622  C C4     . DC  B 2 4  ? -5.64696  -3.63164  -5.96668  1.000 19.26594 ? 20  DC  D C4     1 
ATOM   623  N N4     . DC  B 2 4  ? -6.80061  -3.65018  -5.28619  1.000 19.77043 ? 20  DC  D N4     1 
ATOM   624  C C5     . DC  B 2 4  ? -4.91820  -4.83673  -6.16433  1.000 20.06698 ? 20  DC  D C5     1 
ATOM   625  C C6     . DC  B 2 4  ? -3.77518  -4.76235  -6.85485  1.000 20.94411 ? 20  DC  D C6     1 
ATOM   626  H "H5'"  . DC  B 2 4  ? -2.44752  -6.67069  -10.39164 1.000 35.28246 ? 20  DC  D "H5'"  1 
ATOM   627  H "H5''" . DC  B 2 4  ? -0.89674  -6.96987  -10.38946 1.000 35.28246 ? 20  DC  D "H5''" 1 
ATOM   628  H "H4'"  . DC  B 2 4  ? -1.15370  -4.71916  -10.73094 1.000 30.66692 ? 20  DC  D "H4'"  1 
ATOM   629  H "H3'"  . DC  B 2 4  ? 0.36629   -5.44294  -8.69642  1.000 28.65290 ? 20  DC  D "H3'"  1 
ATOM   630  H "H2'"  . DC  B 2 4  ? -1.05375  -4.88810  -7.03454  1.000 26.77835 ? 20  DC  D "H2'"  1 
ATOM   631  H "H2''" . DC  B 2 4  ? -0.31540  -3.50059  -7.18983  1.000 26.77835 ? 20  DC  D "H2''" 1 
ATOM   632  H "H1'"  . DC  B 2 4  ? -1.90227  -2.63564  -8.42945  1.000 26.41270 ? 20  DC  D "H1'"  1 
ATOM   633  H H41    . DC  B 2 4  ? -7.09951  -4.39056  -4.96665  1.000 23.72452 ? 20  DC  D H41    1 
ATOM   634  H H42    . DC  B 2 4  ? -7.24238  -2.92171  -5.16883  1.000 23.72452 ? 20  DC  D H42    1 
ATOM   635  H H5     . DC  B 2 4  ? -5.22512  -5.64676  -5.82588  1.000 24.08038 ? 20  DC  D H5     1 
ATOM   636  H H6     . DC  B 2 4  ? -3.29030  -5.53832  -7.02114  1.000 25.13293 ? 20  DC  D H6     1 
ATOM   637  P P      . DA  B 2 5  ? 2.16353   -3.50054  -9.24825  1.000 25.87615 ? 21  DA  D P      1 
ATOM   638  O OP1    . DA  B 2 5  ? 2.73391   -2.82757  -10.44798 1.000 30.21556 ? 21  DA  D OP1    1 
ATOM   639  O OP2    . DA  B 2 5  ? 2.74528   -4.77550  -8.76628  1.000 29.12258 ? 21  DA  D OP2    1 
ATOM   640  O "O5'"  . DA  B 2 5  ? 2.15181   -2.51611  -7.98650  1.000 22.95120 ? 21  DA  D "O5'"  1 
ATOM   641  C "C5'"  . DA  B 2 5  ? 1.76935   -1.17351  -8.15516  1.000 20.53929 ? 21  DA  D "C5'"  1 
ATOM   642  C "C4'"  . DA  B 2 5  ? 1.47402   -0.54818  -6.82335  1.000 19.30745 ? 21  DA  D "C4'"  1 
ATOM   643  O "O4'"  . DA  B 2 5  ? 0.20843   -1.05833  -6.34956  1.000 17.82417 ? 21  DA  D "O4'"  1 
ATOM   644  C "C3'"  . DA  B 2 5  ? 2.49127   -0.84956  -5.71325  1.000 18.85173 ? 21  DA  D "C3'"  1 
ATOM   645  O "O3'"  . DA  B 2 5  ? 2.91112   0.36258   -5.11363  1.000 18.28555 ? 21  DA  D "O3'"  1 
ATOM   646  C "C2'"  . DA  B 2 5  ? 1.69614   -1.73553  -4.74409  1.000 18.25348 ? 21  DA  D "C2'"  1 
ATOM   647  C "C1'"  . DA  B 2 5  ? 0.31204   -1.19688  -4.96343  1.000 17.27153 ? 21  DA  D "C1'"  1 
ATOM   648  N N9     . DA  B 2 5  ? -0.77322  -2.01360  -4.46057  1.000 17.86894 ? 21  DA  D N9     1 
ATOM   649  C C8     . DA  B 2 5  ? -0.79052  -3.35873  -4.18164  1.000 18.36315 ? 21  DA  D C8     1 
ATOM   650  N N7     . DA  B 2 5  ? -1.94852  -3.77620  -3.69386  1.000 18.42263 ? 21  DA  D N7     1 
ATOM   651  C C5     . DA  B 2 5  ? -2.71563  -2.62369  -3.65114  1.000 17.97492 ? 21  DA  D C5     1 
ATOM   652  C C6     . DA  B 2 5  ? -4.03752  -2.36887  -3.24356  1.000 18.18919 ? 21  DA  D C6     1 
ATOM   653  N N6     . DA  B 2 5  ? -4.85596  -3.30787  -2.75883  1.000 19.44987 ? 21  DA  D N6     1 
ATOM   654  N N1     . DA  B 2 5  ? -4.48251  -1.10021  -3.32628  1.000 17.88094 ? 21  DA  D N1     1 
ATOM   655  C C2     . DA  B 2 5  ? -3.69019  -0.16836  -3.82207  1.000 18.13393 ? 21  DA  D C2     1 
ATOM   656  N N3     . DA  B 2 5  ? -2.43261  -0.27642  -4.22542  1.000 18.43356 ? 21  DA  D N3     1 
ATOM   657  C C4     . DA  B 2 5  ? -2.01083  -1.54633  -4.13633  1.000 16.79536 ? 21  DA  D C4     1 
ATOM   658  H "H5'"  . DA  B 2 5  ? 0.97738   -1.13165  -8.71367  1.000 24.64714 ? 21  DA  D "H5'"  1 
ATOM   659  H "H5''" . DA  B 2 5  ? 2.48731   -0.68576  -8.58821  1.000 24.64714 ? 21  DA  D "H5''" 1 
ATOM   660  H "H4'"  . DA  B 2 5  ? 1.41791   0.41488   -6.92472  1.000 23.16894 ? 21  DA  D "H4'"  1 
ATOM   661  H "H3'"  . DA  B 2 5  ? 3.24990   -1.34383  -6.06120  1.000 22.62208 ? 21  DA  D "H3'"  1 
ATOM   662  H "H2'"  . DA  B 2 5  ? 1.75951   -2.67461  -4.97866  1.000 21.90418 ? 21  DA  D "H2'"  1 
ATOM   663  H "H2''" . DA  B 2 5  ? 1.98774   -1.61890  -3.82633  1.000 21.90418 ? 21  DA  D "H2''" 1 
ATOM   664  H "H1'"  . DA  B 2 5  ? 0.22333   -0.33466  -4.52799  1.000 20.72584 ? 21  DA  D "H1'"  1 
ATOM   665  H H8     . DA  B 2 5  ? -0.06205  -3.91971  -4.32140  1.000 22.03578 ? 21  DA  D H8     1 
ATOM   666  H H61    . DA  B 2 5  ? -5.65067  -3.09708  -2.50663  1.000 23.33985 ? 21  DA  D H61    1 
ATOM   667  H H62    . DA  B 2 5  ? -4.58785  -4.12282  -2.69914  1.000 23.33985 ? 21  DA  D H62    1 
ATOM   668  H H2     . DA  B 2 5  ? -4.06543  0.67912   -3.89874  1.000 21.76072 ? 21  DA  D H2     1 
ATOM   669  P P      . DC  B 2 6  ? 4.22980   0.42359   -4.20026  1.000 18.29193 ? 22  DC  D P      1 
ATOM   670  O OP1    . DC  B 2 6  ? 4.48304   1.86271   -4.02832  1.000 17.90736 ? 22  DC  D OP1    1 
ATOM   671  O OP2    . DC  B 2 6  ? 5.29974   -0.44583  -4.75197  1.000 19.19310 ? 22  DC  D OP2    1 
ATOM   672  O "O5'"  . DC  B 2 6  ? 3.77185   -0.23280  -2.82542  1.000 18.13001 ? 22  DC  D "O5'"  1 
ATOM   673  C "C5'"  . DC  B 2 6  ? 3.38769   0.54636   -1.72950  1.000 17.65265 ? 22  DC  D "C5'"  1 
ATOM   674  C "C4'"  . DC  B 2 6  ? 2.00492   1.12998   -1.87019  1.000 17.69336 ? 22  DC  D "C4'"  1 
ATOM   675  O "O4'"  . DC  B 2 6  ? 1.03389   0.06587   -2.03928  1.000 17.54175 ? 22  DC  D "O4'"  1 
ATOM   676  C "C3'"  . DC  B 2 6  ? 1.56333   1.91846   -0.62828  1.000 18.09008 ? 22  DC  D "C3'"  1 
ATOM   677  O "O3'"  . DC  B 2 6  ? 1.33757   3.29013   -0.93463  1.000 17.54617 ? 22  DC  D "O3'"  1 
ATOM   678  C "C2'"  . DC  B 2 6  ? 0.30023   1.21133   -0.14821  1.000 19.39944 ? 22  DC  D "C2'"  1 
ATOM   679  C "C1'"  . DC  B 2 6  ? -0.15410  0.42419   -1.36665  1.000 18.11705 ? 22  DC  D "C1'"  1 
ATOM   680  N N1     . DC  B 2 6  ? -0.91192  -0.78013  -0.98466  1.000 16.89218 ? 22  DC  D N1     1 
ATOM   681  C C2     . DC  B 2 6  ? -2.24344  -0.63103  -0.63019  1.000 16.99106 ? 22  DC  D C2     1 
ATOM   682  O O2     . DC  B 2 6  ? -2.74511  0.50033   -0.68664  1.000 17.94262 ? 22  DC  D O2     1 
ATOM   683  N N3     . DC  B 2 6  ? -2.94928  -1.71757  -0.22745  1.000 16.54342 ? 22  DC  D N3     1 
ATOM   684  C C4     . DC  B 2 6  ? -2.34629  -2.91336  -0.16288  1.000 16.95487 ? 22  DC  D C4     1 
ATOM   685  N N4     . DC  B 2 6  ? -3.07167  -3.96444  0.24308   1.000 18.49517 ? 22  DC  D N4     1 
ATOM   686  C C5     . DC  B 2 6  ? -0.96923  -3.07260  -0.49391  1.000 17.58003 ? 22  DC  D C5     1 
ATOM   687  C C6     . DC  B 2 6  ? -0.30139  -1.98937  -0.89715  1.000 17.61225 ? 22  DC  D C6     1 
ATOM   688  H "H5'"  . DC  B 2 6  ? 4.02205   1.27318   -1.62840  1.000 21.18318 ? 22  DC  D "H5'"  1 
ATOM   689  H "H5''" . DC  B 2 6  ? 3.41118   -0.00643  -0.93277  1.000 21.18318 ? 22  DC  D "H5''" 1 
ATOM   690  H "H4'"  . DC  B 2 6  ? 1.95632   1.69343   -2.65826  1.000 21.23203 ? 22  DC  D "H4'"  1 
ATOM   691  H "H3'"  . DC  B 2 6  ? 2.25117   1.83665   0.05074   1.000 21.70810 ? 22  DC  D "H3'"  1 
ATOM   692  H "H2'"  . DC  B 2 6  ? 0.49356   0.62015   0.59613   1.000 23.27932 ? 22  DC  D "H2'"  1 
ATOM   693  H "H2''" . DC  B 2 6  ? -0.37528  1.85184   0.12441   1.000 23.27932 ? 22  DC  D "H2''" 1 
ATOM   694  H "H1'"  . DC  B 2 6  ? -0.69452  0.96057   -1.96760  1.000 21.74046 ? 22  DC  D "H1'"  1 
ATOM   695  H H41    . DC  B 2 6  ? -2.70972  -4.74292  0.29363   1.000 22.19420 ? 22  DC  D H41    1 
ATOM   696  H H42    . DC  B 2 6  ? -3.89914  -3.86050  0.45306   1.000 22.19420 ? 22  DC  D H42    1 
ATOM   697  H H5     . DC  B 2 6  ? -0.55116  -3.90097  -0.43126  1.000 21.09603 ? 22  DC  D H5     1 
ATOM   698  H H6     . DC  B 2 6  ? 0.59787   -2.06449  -1.12206  1.000 21.13470 ? 22  DC  D H6     1 
ATOM   699  P P      . DT  B 2 7  ? 1.35934   4.37003   0.25171   1.000 17.57663 ? 23  DT  D P      1 
ATOM   700  O OP1    . DT  B 2 7  ? 1.36847   5.67620   -0.44119  1.000 17.92259 ? 23  DT  D OP1    1 
ATOM   701  O OP2    . DT  B 2 7  ? 2.46390   4.02525   1.22084   1.000 17.71008 ? 23  DT  D OP2    1 
ATOM   702  O "O5'"  . DT  B 2 7  ? -0.01424  4.17917   0.99846   1.000 16.80696 ? 23  DT  D "O5'"  1 
ATOM   703  C "C5'"  . DT  B 2 7  ? -1.22680  4.47323   0.33420   1.000 18.29301 ? 23  DT  D "C5'"  1 
ATOM   704  C "C4'"  . DT  B 2 7  ? -2.37980  4.30720   1.28150   1.000 17.88482 ? 23  DT  D "C4'"  1 
ATOM   705  O "O4'"  . DT  B 2 7  ? -2.60422  2.89981   1.53405   1.000 17.70335 ? 23  DT  D "O4'"  1 
ATOM   706  C "C3'"  . DT  B 2 7  ? -2.18864  4.95452   2.66047   1.000 17.86325 ? 23  DT  D "C3'"  1 
ATOM   707  O "O3'"  . DT  B 2 7  ? -3.33203  5.74955   2.92519   1.000 18.73045 ? 23  DT  D "O3'"  1 
ATOM   708  C "C2'"  . DT  B 2 7  ? -2.04593  3.76158   3.62177   1.000 18.01353 ? 23  DT  D "C2'"  1 
ATOM   709  C "C1'"  . DT  B 2 7  ? -2.87060  2.70827   2.93109   1.000 16.54025 ? 23  DT  D "C1'"  1 
ATOM   710  N N1     . DT  B 2 7  ? -2.58339  1.28949   3.18053   1.000 17.19562 ? 23  DT  D N1     1 
ATOM   711  C C2     . DT  B 2 7  ? -3.62540  0.46591   3.51038   1.000 17.48921 ? 23  DT  D C2     1 
ATOM   712  O O2     . DT  B 2 7  ? -4.75314  0.86648   3.78903   1.000 18.50047 ? 23  DT  D O2     1 
ATOM   713  N N3     . DT  B 2 7  ? -3.31573  -0.84995  3.57120   1.000 17.78027 ? 23  DT  D N3     1 
ATOM   714  C C4     . DT  B 2 7  ? -2.10684  -1.44254  3.33158   1.000 16.82696 ? 23  DT  D C4     1 
ATOM   715  O O4     . DT  B 2 7  ? -1.96575  -2.65845  3.41065   1.000 19.06448 ? 23  DT  D O4     1 
ATOM   716  C C5     . DT  B 2 7  ? -1.02247  -0.53579  3.02714   1.000 17.49239 ? 23  DT  D C5     1 
ATOM   717  C C7     . DT  B 2 7  ? 0.36439   -1.06326  2.78916   1.000 18.76553 ? 23  DT  D C7     1 
ATOM   718  C C6     . DT  B 2 7  ? -1.31409  0.77743   2.93564   1.000 17.08174 ? 23  DT  D C6     1 
ATOM   719  H "H5'"  . DT  B 2 7  ? -1.33742  3.87206   -0.41896  1.000 21.95161 ? 23  DT  D "H5'"  1 
ATOM   720  H "H5''" . DT  B 2 7  ? -1.20430  5.38665   0.00853   1.000 21.95161 ? 23  DT  D "H5''" 1 
ATOM   721  H "H4'"  . DT  B 2 7  ? -3.17704  4.67836   0.87218   1.000 21.46178 ? 23  DT  D "H4'"  1 
ATOM   722  H "H3'"  . DT  B 2 7  ? -1.37003  5.47294   2.70543   1.000 21.43590 ? 23  DT  D "H3'"  1 
ATOM   723  H "H2'"  . DT  B 2 7  ? -1.12017  3.48600   3.71080   1.000 21.61623 ? 23  DT  D "H2'"  1 
ATOM   724  H "H2''" . DT  B 2 7  ? -2.39944  3.96956   4.50079   1.000 21.61623 ? 23  DT  D "H2''" 1 
ATOM   725  H "H1'"  . DT  B 2 7  ? -3.78651  2.87047   3.20622   1.000 19.84830 ? 23  DT  D "H1'"  1 
ATOM   726  H H3     . DT  B 2 7  ? -3.95853  -1.37885  3.78722   1.000 21.33633 ? 23  DT  D H3     1 
ATOM   727  H H71    . DT  B 2 7  ? 0.48082   -1.88407  3.29276   1.000 22.51864 ? 23  DT  D H71    1 
ATOM   728  H H72    . DT  B 2 7  ? 0.47769   -1.23759  1.84170   1.000 22.51864 ? 23  DT  D H72    1 
ATOM   729  H H73    . DT  B 2 7  ? 1.00901   -0.40065  3.08297   1.000 22.51864 ? 23  DT  D H73    1 
ATOM   730  H H6     . DT  B 2 7  ? -0.63559  1.36739   2.69799   1.000 20.49808 ? 23  DT  D H6     1 
ATOM   731  P P      . DT  B 2 8  ? -3.38638  6.78997   4.13153   1.000 19.69863 ? 24  DT  D P      1 
ATOM   732  O OP1    . DT  B 2 8  ? -4.29203  7.87353   3.73645   1.000 21.82516 ? 24  DT  D OP1    1 
ATOM   733  O OP2    . DT  B 2 8  ? -2.01915  7.05319   4.64903   1.000 19.93546 ? 24  DT  D OP2    1 
ATOM   734  O "O5'"  . DT  B 2 8  ? -4.08408  5.94611   5.28313   1.000 18.73843 ? 24  DT  D "O5'"  1 
ATOM   735  C "C5'"  . DT  B 2 8  ? -5.43150  5.57656   5.13883   1.000 19.10982 ? 24  DT  D "C5'"  1 
ATOM   736  C "C4'"  . DT  B 2 8  ? -5.82654  4.55078   6.17886   1.000 19.60542 ? 24  DT  D "C4'"  1 
ATOM   737  O "O4'"  . DT  B 2 8  ? -5.15235  3.28890   5.95427   1.000 18.58978 ? 24  DT  D "O4'"  1 
ATOM   738  C "C3'"  . DT  B 2 8  ? -5.50081  4.93943   7.62152   1.000 21.21601 ? 24  DT  D "C3'"  1 
ATOM   739  O "O3'"  . DT  B 2 8  ? -6.73861  5.23724   8.27223   1.000 23.67202 ? 24  DT  D "O3'"  1 
ATOM   740  C "C2'"  . DT  B 2 8  ? -4.76758  3.70654   8.20099   1.000 22.86496 ? 24  DT  D "C2'"  1 
ATOM   741  C "C1'"  . DT  B 2 8  ? -5.11421  2.62594   7.20413   1.000 20.16378 ? 24  DT  D "C1'"  1 
ATOM   742  N N1     . DT  B 2 8  ? -4.16587  1.48448   7.09466   1.000 18.42416 ? 24  DT  D N1     1 
ATOM   743  C C2     . DT  B 2 8  ? -4.65180  0.21204   7.28643   1.000 19.71493 ? 24  DT  D C2     1 
ATOM   744  O O2     . DT  B 2 8  ? -5.80264  -0.02181  7.61854   1.000 21.76842 ? 24  DT  D O2     1 
ATOM   745  N N3     . DT  B 2 8  ? -3.72672  -0.78246  7.12345   1.000 19.60838 ? 24  DT  D N3     1 
ATOM   746  C C4     . DT  B 2 8  ? -2.40325  -0.64466  6.77619   1.000 20.33536 ? 24  DT  D C4     1 
ATOM   747  O O4     . DT  B 2 8  ? -1.68129  -1.61131  6.61137   1.000 20.18536 ? 24  DT  D O4     1 
ATOM   748  C C5     . DT  B 2 8  ? -1.95011  0.71076   6.56679   1.000 17.90926 ? 24  DT  D C5     1 
ATOM   749  C C7     . DT  B 2 8  ? -0.50639  0.97256   6.20162   1.000 19.28548 ? 24  DT  D C7     1 
ATOM   750  C C6     . DT  B 2 8  ? -2.84413  1.70439   6.73189   1.000 18.57271 ? 24  DT  D C6     1 
ATOM   751  H "H5'"  . DT  B 2 8  ? -5.56680  5.20245   4.25416   1.000 22.93178 ? 24  DT  D "H5'"  1 
ATOM   752  H "H5''" . DT  B 2 8  ? -5.99048  6.36309   5.23798   1.000 22.93178 ? 24  DT  D "H5''" 1 
ATOM   753  H "H4'"  . DT  B 2 8  ? -6.77940  4.39075   6.09305   1.000 23.52650 ? 24  DT  D "H4'"  1 
ATOM   754  H "H3'"  . DT  B 2 8  ? -4.88211  5.68502   7.66848   1.000 25.45921 ? 24  DT  D "H3'"  1 
ATOM   755  H "H2'"  . DT  B 2 8  ? -3.80971  3.85329   8.24386   1.000 27.43796 ? 24  DT  D "H2'"  1 
ATOM   756  H "H2''" . DT  B 2 8  ? -5.09336  3.48652   9.08777   1.000 27.43796 ? 24  DT  D "H2''" 1 
ATOM   757  H "H1'"  . DT  B 2 8  ? -5.97695  2.25431   7.44591   1.000 24.19653 ? 24  DT  D "H1'"  1 
ATOM   758  H H3     . DT  B 2 8  ? -4.00467  -1.58592  7.25301   1.000 23.53005 ? 24  DT  D H3     1 
ATOM   759  H H71    . DT  B 2 8  ? -0.47095  1.68664   5.54608   1.000 23.14257 ? 24  DT  D H71    1 
ATOM   760  H H72    . DT  B 2 8  ? -0.02075  1.23219   7.00014   1.000 23.14257 ? 24  DT  D H72    1 
ATOM   761  H H73    . DT  B 2 8  ? -0.12287  0.16288   5.82982   1.000 23.14257 ? 24  DT  D H73    1 
ATOM   762  H H6     . DT  B 2 8  ? -2.56233  2.58024   6.59630   1.000 22.28725 ? 24  DT  D H6     1 
ATOM   763  P P      . DT  B 2 9  ? -6.81596  5.64600   9.81983   1.000 27.05522 ? 25  DT  D P      1 
ATOM   764  O OP1    . DT  B 2 9  ? -8.12277  6.35262   10.00032  1.000 29.88512 ? 25  DT  D OP1    1 
ATOM   765  O OP2    . DT  B 2 9  ? -5.54585  6.29323   10.22246  1.000 25.18649 ? 25  DT  D OP2    1 
ATOM   766  O "O5'"  . DT  B 2 9  ? -6.90165  4.23534   10.57293  1.000 29.43247 ? 25  DT  D "O5'"  1 
ATOM   767  C "C5'"  . DT  B 2 9  ? -8.08695  3.46341   10.44387  1.000 34.78947 ? 25  DT  D "C5'"  1 
ATOM   768  C "C4'"  . DT  B 2 9  ? -8.00235  2.21283   11.27510  1.000 37.91590 ? 25  DT  D "C4'"  1 
ATOM   769  O "O4'"  . DT  B 2 9  ? -6.98336  1.35685   10.71976  1.000 34.79756 ? 25  DT  D "O4'"  1 
ATOM   770  C "C3'"  . DT  B 2 9  ? -7.61916  2.44064   12.73637  1.000 43.12916 ? 25  DT  D "C3'"  1 
ATOM   771  O "O3'"  . DT  B 2 9  ? -8.71738  2.12689   13.56095  1.000 51.56288 ? 25  DT  D "O3'"  1 
ATOM   772  C "C2'"  . DT  B 2 9  ? -6.40956  1.52066   12.97035  1.000 38.91955 ? 25  DT  D "C2'"  1 
ATOM   773  C "C1'"  . DT  B 2 9  ? -6.41943  0.60262   11.75163  1.000 33.55026 ? 25  DT  D "C1'"  1 
ATOM   774  N N1     . DT  B 2 9  ? -5.09160  0.16762   11.28206  1.000 29.22934 ? 25  DT  D N1     1 
ATOM   775  C C2     . DT  B 2 9  ? -4.82052  -1.17591  11.13566  1.000 27.79848 ? 25  DT  D C2     1 
ATOM   776  O O2     . DT  B 2 9  ? -5.60026  -2.05401  11.41698  1.000 31.53389 ? 25  DT  D O2     1 
ATOM   777  N N3     . DT  B 2 9  ? -3.58307  -1.45729  10.64553  1.000 21.77507 ? 25  DT  D N3     1 
ATOM   778  C C4     . DT  B 2 9  ? -2.60067  -0.55065  10.32000  1.000 22.88978 ? 25  DT  D C4     1 
ATOM   779  O O4     . DT  B 2 9  ? -1.50068  -0.89388  9.88874   1.000 21.35567 ? 25  DT  D O4     1 
ATOM   780  C C5     . DT  B 2 9  ? -2.96354  0.84204   10.50401  1.000 23.25255 ? 25  DT  D C5     1 
ATOM   781  C C7     . DT  B 2 9  ? -1.98604  1.92653   10.14946  1.000 25.32115 ? 25  DT  D C7     1 
ATOM   782  C C6     . DT  B 2 9  ? -4.18359  1.12191   10.93810  1.000 27.79735 ? 25  DT  D C6     1 
ATOM   783  H "H5'"  . DT  B 2 9  ? -8.21111  3.22100   9.51289   1.000 41.74737 ? 25  DT  D "H5'"  1 
ATOM   784  H "H5''" . DT  B 2 9  ? -8.84612  3.99145   10.73667  1.000 41.74737 ? 25  DT  D "H5''" 1 
ATOM   785  H "H4'"  . DT  B 2 9  ? -8.85171  1.74489   11.25213  1.000 45.49908 ? 25  DT  D "H4'"  1 
ATOM   786  H "H3'"  . DT  B 2 9  ? -7.33198  3.35737   12.87067  1.000 51.75499 ? 25  DT  D "H3'"  1 
ATOM   787  H "H2'"  . DT  B 2 9  ? -5.58630  2.03167   13.01537  1.000 46.70346 ? 25  DT  D "H2'"  1 
ATOM   788  H "H2''" . DT  B 2 9  ? -6.51121  1.01270   13.79044  1.000 46.70346 ? 25  DT  D "H2''" 1 
ATOM   789  H "H1'"  . DT  B 2 9  ? -6.95424  -0.17877  11.96212  1.000 40.26031 ? 25  DT  D "H1'"  1 
ATOM   790  H H3     . DT  B 2 9  ? -3.39536  -2.28811  10.52683  1.000 26.13009 ? 25  DT  D H3     1 
ATOM   791  H H71    . DT  B 2 9  ? -2.38531  2.50553   9.48144   1.000 30.38538 ? 25  DT  D H71    1 
ATOM   792  H H72    . DT  B 2 9  ? -1.77746  2.43694   10.94750  1.000 30.38538 ? 25  DT  D H72    1 
ATOM   793  H H73    . DT  B 2 9  ? -1.17895  1.52096   9.79586   1.000 30.38538 ? 25  DT  D H73    1 
ATOM   794  H H6     . DT  B 2 9  ? -4.43222  2.01504   11.01153  1.000 33.35682 ? 25  DT  D H6     1 
ATOM   795  P P      . DC  B 2 10 ? -8.69524  2.46122   15.13476  1.000 54.06252 ? 26  DC  D P      1 
ATOM   796  O OP1    . DC  B 2 10 ? -10.08744 2.40694   15.63996  1.000 57.73971 ? 26  DC  D OP1    1 
ATOM   797  O OP2    . DC  B 2 10 ? -7.88177  3.68287   15.34276  1.000 55.00301 ? 26  DC  D OP2    1 
ATOM   798  O "O5'"  . DC  B 2 10 ? -7.88542  1.24504   15.75465  1.000 57.12963 ? 26  DC  D "O5'"  1 
ATOM   799  C "C5'"  . DC  B 2 10 ? -8.37567  -0.06351  15.59783  1.000 58.15074 ? 26  DC  D "C5'"  1 
ATOM   800  C "C4'"  . DC  B 2 10 ? -7.34852  -1.08643  16.03821  1.000 58.42728 ? 26  DC  D "C4'"  1 
ATOM   801  O "O4'"  . DC  B 2 10 ? -6.23408  -1.07166  15.12963  1.000 57.34311 ? 26  DC  D "O4'"  1 
ATOM   802  C "C3'"  . DC  B 2 10 ? -6.74268  -0.85774  17.42747  1.000 58.72244 ? 26  DC  D "C3'"  1 
ATOM   803  O "O3'"  . DC  B 2 10 ? -7.30675  -1.78024  18.35087  1.000 59.73289 ? 26  DC  D "O3'"  1 
ATOM   804  C "C2'"  . DC  B 2 10 ? -5.22993  -1.06846  17.22468  1.000 57.85548 ? 26  DC  D "C2'"  1 
ATOM   805  C "C1'"  . DC  B 2 10 ? -5.13261  -1.60637  15.80207  1.000 56.66316 ? 26  DC  D "C1'"  1 
ATOM   806  N N1     . DC  B 2 10 ? -3.87704  -1.22766  15.07060  1.000 54.00265 ? 26  DC  D N1     1 
ATOM   807  C C2     . DC  B 2 10 ? -3.11506  -2.22608  14.45433  1.000 49.95616 ? 26  DC  D C2     1 
ATOM   808  O O2     . DC  B 2 10 ? -3.49416  -3.39533  14.51798  1.000 48.83456 ? 26  DC  D O2     1 
ATOM   809  N N3     . DC  B 2 10 ? -1.98402  -1.88184  13.79600  1.000 48.26464 ? 26  DC  D N3     1 
ATOM   810  C C4     . DC  B 2 10 ? -1.60526  -0.60926  13.73795  1.000 48.92459 ? 26  DC  D C4     1 
ATOM   811  N N4     . DC  B 2 10 ? -0.48381  -0.32902  13.07341  1.000 45.07209 ? 26  DC  D N4     1 
ATOM   812  C C5     . DC  B 2 10 ? -2.36345  0.43114   14.35969  1.000 52.21775 ? 26  DC  D C5     1 
ATOM   813  C C6     . DC  B 2 10 ? -3.48500  0.07933   15.00745  1.000 53.93213 ? 26  DC  D C6     1 
ATOM   814  H "H5'"  . DC  B 2 10 ? -8.59397  -0.21240  14.66452  1.000 69.78089 ? 26  DC  D "H5'"  1 
ATOM   815  H "H5''" . DC  B 2 10 ? -9.17925  -0.16885  16.13081  1.000 69.78089 ? 26  DC  D "H5''" 1 
ATOM   816  H "H4'"  . DC  B 2 10 ? -7.76134  -1.96402  16.02041  1.000 70.11273 ? 26  DC  D "H4'"  1 
ATOM   817  H "H3'"  . DC  B 2 10 ? -6.89266  0.05699   17.71327  1.000 70.46693 ? 26  DC  D "H3'"  1 
ATOM   818  H "H2'"  . DC  B 2 10 ? -4.74627  -0.23253  17.31518  1.000 69.42658 ? 26  DC  D "H2'"  1 
ATOM   819  H "H2''" . DC  B 2 10 ? -4.87818  -1.70764  17.86392  1.000 69.42658 ? 26  DC  D "H2''" 1 
ATOM   820  H "H1'"  . DC  B 2 10 ? -5.18722  -2.57473  15.81605  1.000 67.99579 ? 26  DC  D "H1'"  1 
ATOM   821  H H41    . DC  B 2 10 ? -0.20969  0.48411   13.01615  1.000 54.08651 ? 26  DC  D H41    1 
ATOM   822  H H42    . DC  B 2 10 ? -0.03461  -0.96140  12.70204  1.000 54.08651 ? 26  DC  D H42    1 
ATOM   823  H H5     . DC  B 2 10 ? -2.08963  1.31888   14.31687  1.000 62.66130 ? 26  DC  D H5     1 
ATOM   824  H H6     . DC  B 2 10 ? -4.00201  0.73393   15.41868  1.000 64.71856 ? 26  DC  D H6     1 
ATOM   825  P P      . DG  B 2 11 ? -6.81252  -1.86036  19.87980  1.000 60.94518 ? 27  DG  D P      1 
ATOM   826  O OP1    . DG  B 2 11 ? -8.01255  -2.24662  20.64152  1.000 63.39829 ? 27  DG  D OP1    1 
ATOM   827  O OP2    . DG  B 2 11 ? -6.07787  -0.63731  20.26105  1.000 64.32656 ? 27  DG  D OP2    1 
ATOM   828  O "O5'"  . DG  B 2 11 ? -5.79277  -3.09353  19.87661  1.000 59.66088 ? 27  DG  D "O5'"  1 
ATOM   829  C "C5'"  . DG  B 2 11 ? -6.25483  -4.37270  19.44773  1.000 57.20028 ? 27  DG  D "C5'"  1 
ATOM   830  C "C4'"  . DG  B 2 11 ? -5.12103  -5.37844  19.34429  1.000 53.11698 ? 27  DG  D "C4'"  1 
ATOM   831  O "O4'"  . DG  B 2 11 ? -4.19109  -4.95224  18.31180  1.000 49.99669 ? 27  DG  D "O4'"  1 
ATOM   832  C "C3'"  . DG  B 2 11 ? -4.29658  -5.56485  20.62272  1.000 51.86934 ? 27  DG  D "C3'"  1 
ATOM   833  O "O3'"  . DG  B 2 11 ? -4.21669  -6.95526  20.96044  1.000 53.38774 ? 27  DG  D "O3'"  1 
ATOM   834  C "C2'"  . DG  B 2 11 ? -2.93842  -4.96439  20.27052  1.000 48.38254 ? 27  DG  D "C2'"  1 
ATOM   835  C "C1'"  . DG  B 2 11 ? -2.87813  -5.12844  18.75917  1.000 46.63155 ? 27  DG  D "C1'"  1 
ATOM   836  N N9     . DG  B 2 11 ? -2.01965  -4.15169  18.08898  1.000 43.95541 ? 27  DG  D N9     1 
ATOM   837  C C8     . DG  B 2 11 ? -2.09722  -2.78262  18.18717  1.000 44.61247 ? 27  DG  D C8     1 
ATOM   838  N N7     . DG  B 2 11 ? -1.20306  -2.15899  17.47428  1.000 42.73114 ? 27  DG  D N7     1 
ATOM   839  C C5     . DG  B 2 11 ? -0.48726  -3.17946  16.85991  1.000 39.70808 ? 27  DG  D C5     1 
ATOM   840  C C6     . DG  B 2 11 ? 0.61438   -3.11381  15.98545  1.000 37.37750 ? 27  DG  D C6     1 
ATOM   841  O O6     . DG  B 2 11 ? 1.19142   -2.11109  15.56538  1.000 37.54292 ? 27  DG  D O6     1 
ATOM   842  N N1     . DG  B 2 11 ? 1.04329   -4.37897  15.59880  1.000 36.35677 ? 27  DG  D N1     1 
ATOM   843  C C2     . DG  B 2 11 ? 0.46697   -5.55969  16.00050  1.000 37.94181 ? 27  DG  D C2     1 
ATOM   844  N N2     . DG  B 2 11 ? 1.01216   -6.68610  15.52675  1.000 39.98360 ? 27  DG  D N2     1 
ATOM   845  N N3     . DG  B 2 11 ? -0.56102  -5.63454  16.83181  1.000 38.40639 ? 27  DG  D N3     1 
ATOM   846  C C4     . DG  B 2 11 ? -0.98397  -4.41124  17.22026  1.000 40.78845 ? 27  DG  D C4     1 
ATOM   847  H "H5'"  . DG  B 2 11 ? -6.67557  -4.28105  18.57854  1.000 68.64033 ? 27  DG  D "H5'"  1 
ATOM   848  H "H5''" . DG  B 2 11 ? -6.91048  -4.70060  20.08295  1.000 68.64033 ? 27  DG  D "H5''" 1 
ATOM   849  H "H4'"  . DG  B 2 11 ? -5.48264  -6.24207  19.09075  1.000 63.74037 ? 27  DG  D "H4'"  1 
ATOM   850  H "H3'"  . DG  B 2 11 ? -4.68895  -5.06011  21.35223  1.000 62.24320 ? 27  DG  D "H3'"  1 
ATOM   851  H "H2'"  . DG  B 2 11 ? -2.89114  -4.02944  20.52456  1.000 58.05905 ? 27  DG  D "H2'"  1 
ATOM   852  H "H2''" . DG  B 2 11 ? -2.21774  -5.44659  20.70525  1.000 58.05905 ? 27  DG  D "H2''" 1 
ATOM   853  H "H1'"  . DG  B 2 11 ? -2.56728  -6.02001  18.53696  1.000 55.95786 ? 27  DG  D "H1'"  1 
ATOM   854  H H8     . DG  B 2 11 ? -2.72736  -2.34401  18.71200  1.000 53.53496 ? 27  DG  D H8     1 
ATOM   855  H H1     . DG  B 2 11 ? 1.71922   -4.42571  15.06914  1.000 43.62812 ? 27  DG  D H1     1 
ATOM   856  H H21    . DG  B 2 11 ? 0.69468   -7.44976  15.76261  1.000 47.98032 ? 27  DG  D H21    1 
ATOM   857  H H22    . DG  B 2 11 ? 1.68003   -6.64639  14.98640  1.000 47.98032 ? 27  DG  D H22    1 
ATOM   858  P P      . DC  B 2 12 ? -3.39568  -7.45740  22.25168  1.000 55.89110 ? 28  DC  D P      1 
ATOM   859  O OP1    . DC  B 2 12 ? -4.00573  -8.73533  22.67307  1.000 58.67848 ? 28  DC  D OP1    1 
ATOM   860  O OP2    . DC  B 2 12 ? -3.27406  -6.33350  23.21025  1.000 57.96723 ? 28  DC  D OP2    1 
ATOM   861  O "O5'"  . DC  B 2 12 ? -1.95004  -7.78059  21.66910  1.000 52.02633 ? 28  DC  D "O5'"  1 
ATOM   862  C "C5'"  . DC  B 2 12 ? -1.81909  -8.78144  20.68637  1.000 47.05613 ? 28  DC  D "C5'"  1 
ATOM   863  C "C4'"  . DC  B 2 12 ? -0.39653  -8.88379  20.23100  1.000 42.79476 ? 28  DC  D "C4'"  1 
ATOM   864  O "O4'"  . DC  B 2 12 ? -0.02678  -7.65840  19.58037  1.000 39.59071 ? 28  DC  D "O4'"  1 
ATOM   865  C "C3'"  . DC  B 2 12 ? 0.61412   -9.08569  21.36149  1.000 41.09431 ? 28  DC  D "C3'"  1 
ATOM   866  O "O3'"  . DC  B 2 12 ? 1.27013   -10.30990 21.19042  1.000 42.65474 ? 28  DC  D "O3'"  1 
ATOM   867  C "C2'"  . DC  B 2 12 ? 1.56240   -7.89000  21.23884  1.000 40.10258 ? 28  DC  D "C2'"  1 
ATOM   868  C "C1'"  . DC  B 2 12 ? 1.33130   -7.44555  19.81007  1.000 38.05979 ? 28  DC  D "C1'"  1 
ATOM   869  N N1     . DC  B 2 12 ? 1.64122   -6.03333  19.54787  1.000 34.66285 ? 28  DC  D N1     1 
ATOM   870  C C2     . DC  B 2 12 ? 2.72937   -5.72423  18.74707  1.000 31.04672 ? 28  DC  D C2     1 
ATOM   871  O O2     . DC  B 2 12 ? 3.39517   -6.64546  18.27097  1.000 33.12562 ? 28  DC  D O2     1 
ATOM   872  N N3     . DC  B 2 12 ? 3.02169   -4.42708  18.51087  1.000 30.60381 ? 28  DC  D N3     1 
ATOM   873  C C4     . DC  B 2 12 ? 2.26730   -3.46732  19.03444  1.000 31.78550 ? 28  DC  D C4     1 
ATOM   874  N N4     . DC  B 2 12 ? 2.59530   -2.20517  18.76555  1.000 31.27466 ? 28  DC  D N4     1 
ATOM   875  C C5     . DC  B 2 12 ? 1.14771   -3.76011  19.85834  1.000 32.72500 ? 28  DC  D C5     1 
ATOM   876  C C6     . DC  B 2 12 ? 0.87847   -5.04817  20.09606  1.000 32.77052 ? 28  DC  D C6     1 
ATOM   877  H "H5'"  . DC  B 2 12 ? -2.38419  -8.56370  19.92864  1.000 56.46736 ? 28  DC  D "H5'"  1 
ATOM   878  H "H5''" . DC  B 2 12 ? -2.10037  -9.63316  21.05565  1.000 56.46736 ? 28  DC  D "H5''" 1 
ATOM   879  H "H4'"  . DC  B 2 12 ? -0.30468  -9.61177  19.59656  1.000 51.35372 ? 28  DC  D "H4'"  1 
ATOM   880  H "H3'"  . DC  B 2 12 ? 0.16852   -9.04483  22.22211  1.000 49.31317 ? 28  DC  D "H3'"  1 
ATOM   881  H "H2'"  . DC  B 2 12 ? 1.33212   -7.18951  21.86906  1.000 48.12310 ? 28  DC  D "H2'"  1 
ATOM   882  H "H2''" . DC  B 2 12 ? 2.48476   -8.15354  21.38274  1.000 48.12310 ? 28  DC  D "H2''" 1 
ATOM   883  H "H1'"  . DC  B 2 12 ? 1.86733   -7.98617  19.20899  1.000 45.67175 ? 28  DC  D "H1'"  1 
ATOM   884  H H41    . DC  B 2 12 ? 2.12685   -1.56079  19.08948  1.000 37.52959 ? 28  DC  D H41    1 
ATOM   885  H H42    . DC  B 2 12 ? 3.27560   -2.03434  18.26795  1.000 37.52959 ? 28  DC  D H42    1 
ATOM   886  H H5     . DC  B 2 12 ? 0.62245   -3.08234  20.21839  1.000 39.27000 ? 28  DC  D H5     1 
ATOM   887  H H6     . DC  B 2 12 ? 0.16089   -5.27380  20.64293  1.000 39.32462 ? 28  DC  D H6     1 
ATOM   888  P P      . DT  B 2 13 ? 2.26144   -10.86753 22.32165  1.000 45.67867 ? 29  DT  D P      1 
ATOM   889  O OP1    . DT  B 2 13 ? 2.18196   -12.34456 22.25461  1.000 47.15751 ? 29  DT  D OP1    1 
ATOM   890  O OP2    . DT  B 2 13 ? 1.99466   -10.16269 23.60016  1.000 48.91612 ? 29  DT  D OP2    1 
ATOM   891  O "O5'"  . DT  B 2 13 ? 3.70063   -10.42722 21.80916  1.000 42.56837 ? 29  DT  D "O5'"  1 
ATOM   892  C "C5'"  . DT  B 2 13 ? 4.15557   -10.89984 20.56772  1.000 39.40808 ? 29  DT  D "C5'"  1 
ATOM   893  C "C4'"  . DT  B 2 13 ? 5.57441   -10.46615 20.32355  1.000 36.47707 ? 29  DT  D "C4'"  1 
ATOM   894  O "O4'"  . DT  B 2 13 ? 5.59543   -9.05425  20.02587  1.000 34.41916 ? 29  DT  D "O4'"  1 
ATOM   895  C "C3'"  . DT  B 2 13 ? 6.51586   -10.67046 21.51400  1.000 34.39387 ? 29  DT  D "C3'"  1 
ATOM   896  O "O3'"  . DT  B 2 13 ? 7.67526   -11.36840 21.07573  1.000 34.99487 ? 29  DT  D "O3'"  1 
ATOM   897  C "C2'"  . DT  B 2 13 ? 6.81217   -9.24464  22.00096  1.000 32.86127 ? 29  DT  D "C2'"  1 
ATOM   898  C "C1'"  . DT  B 2 13 ? 6.65599   -8.43987  20.72486  1.000 31.88706 ? 29  DT  D "C1'"  1 
ATOM   899  N N1     . DT  B 2 13 ? 6.30071   -7.00288  20.89281  1.000 29.49957 ? 29  DT  D N1     1 
ATOM   900  C C2     . DT  B 2 13 ? 7.06190   -6.04669  20.25687  1.000 28.54972 ? 29  DT  D C2     1 
ATOM   901  O O2     . DT  B 2 13 ? 8.06648   -6.30673  19.61688  1.000 28.36160 ? 29  DT  D O2     1 
ATOM   902  N N3     . DT  B 2 13 ? 6.63535   -4.76365  20.43389  1.000 27.26443 ? 29  DT  D N3     1 
ATOM   903  C C4     . DT  B 2 13 ? 5.52295   -4.34457  21.13521  1.000 27.72900 ? 29  DT  D C4     1 
ATOM   904  O O4     . DT  B 2 13 ? 5.20559   -3.16001  21.21183  1.000 27.70254 ? 29  DT  D O4     1 
ATOM   905  C C5     . DT  B 2 13 ? 4.76011   -5.39767  21.76989  1.000 28.84646 ? 29  DT  D C5     1 
ATOM   906  C C7     . DT  B 2 13 ? 3.54441   -5.06514  22.57105  1.000 30.79606 ? 29  DT  D C7     1 
ATOM   907  C C6     . DT  B 2 13 ? 5.16727   -6.66209  21.60498  1.000 29.24814 ? 29  DT  D C6     1 
ATOM   908  H "H5'"  . DT  B 2 13 ? 3.58763   -10.54958 19.86368  1.000 47.28969 ? 29  DT  D "H5'"  1 
ATOM   909  H "H5''" . DT  B 2 13 ? 4.11023   -11.86872 20.55739  1.000 47.28969 ? 29  DT  D "H5''" 1 
ATOM   910  H "H4'"  . DT  B 2 13 ? 5.93460   -10.94352 19.55982  1.000 43.77248 ? 29  DT  D "H4'"  1 
ATOM   911  H "H3'"  . DT  B 2 13 ? 6.07356   -11.15195 22.23055  1.000 41.27264 ? 29  DT  D "H3'"  1 
ATOM   912  H "H2'"  . DT  B 2 13 ? 6.17821   -8.96209  22.67857  1.000 39.43352 ? 29  DT  D "H2'"  1 
ATOM   913  H "H2''" . DT  B 2 13 ? 7.71069   -9.17143  22.35900  1.000 39.43352 ? 29  DT  D "H2''" 1 
ATOM   914  H "H1'"  . DT  B 2 13 ? 7.49175   -8.48832  20.23490  1.000 38.26448 ? 29  DT  D "H1'"  1 
ATOM   915  H H3     . DT  B 2 13 ? 7.11180   -4.14800  20.06841  1.000 32.71731 ? 29  DT  D H3     1 
ATOM   916  H H71    . DT  B 2 13 ? 2.76851   -5.46563  22.14859  1.000 36.95527 ? 29  DT  D H71    1 
ATOM   917  H H72    . DT  B 2 13 ? 3.65136   -5.41771  23.46835  1.000 36.95527 ? 29  DT  D H72    1 
ATOM   918  H H73    . DT  B 2 13 ? 3.44216   -4.10112  22.60444  1.000 36.95527 ? 29  DT  D H73    1 
ATOM   919  H H6     . DT  B 2 13 ? 4.66321   -7.34335  21.98801  1.000 35.09777 ? 29  DT  D H6     1 
ATOM   920  P P      . DT  B 2 14 ? 8.77394   -11.92106 22.10049  1.000 34.35711 ? 30  DT  D P      1 
ATOM   921  O OP1    . DT  B 2 14 ? 9.33374   -13.13824 21.47934  1.000 37.11372 ? 30  DT  D OP1    1 
ATOM   922  O OP2    . DT  B 2 14 ? 8.20556   -11.98464 23.46861  1.000 33.53535 ? 30  DT  D OP2    1 
ATOM   923  O "O5'"  . DT  B 2 14 ? 9.88617   -10.78744 22.09225  1.000 33.57055 ? 30  DT  D "O5'"  1 
ATOM   924  C "C5'"  . DT  B 2 14 ? 10.57910  -10.51187 20.90536  1.000 31.51671 ? 30  DT  D "C5'"  1 
ATOM   925  C "C4'"  . DT  B 2 14 ? 11.38473  -9.25165  21.05526  1.000 29.67872 ? 30  DT  D "C4'"  1 
ATOM   926  O "O4'"  . DT  B 2 14 ? 10.50018  -8.15046  21.33827  1.000 28.65241 ? 30  DT  D "O4'"  1 
ATOM   927  C "C3'"  . DT  B 2 14 ? 12.40940  -9.26403  22.19736  1.000 28.96912 ? 30  DT  D "C3'"  1 
ATOM   928  O "O3'"  . DT  B 2 14 ? 13.71365  -9.16586  21.63110  1.000 29.93357 ? 30  DT  D "O3'"  1 
ATOM   929  C "C2'"  . DT  B 2 14 ? 12.01485  -8.04859  23.07454  1.000 27.39674 ? 30  DT  D "C2'"  1 
ATOM   930  C "C1'"  . DT  B 2 14 ? 11.20959  -7.21300  22.09596  1.000 27.18596 ? 30  DT  D "C1'"  1 
ATOM   931  N N1     . DT  B 2 14 ? 10.20189  -6.24878  22.65102  1.000 26.97403 ? 30  DT  D N1     1 
ATOM   932  C C2     . DT  B 2 14 ? 10.25415  -4.94205  22.23710  1.000 27.47013 ? 30  DT  D C2     1 
ATOM   933  O O2     . DT  B 2 14 ? 11.13673  -4.50947  21.53810  1.000 26.88794 ? 30  DT  D O2     1 
ATOM   934  N N3     . DT  B 2 14 ? 9.26105   -4.14310  22.71295  1.000 26.38059 ? 30  DT  D N3     1 
ATOM   935  C C4     . DT  B 2 14 ? 8.20932   -4.51374  23.51477  1.000 28.60197 ? 30  DT  D C4     1 
ATOM   936  O O4     . DT  B 2 14 ? 7.35468   -3.70582  23.87656  1.000 29.23916 ? 30  DT  D O4     1 
ATOM   937  C C5     . DT  B 2 14 ? 8.19087   -5.91199  23.90316  1.000 28.61229 ? 30  DT  D C5     1 
ATOM   938  C C7     . DT  B 2 14 ? 7.09710   -6.44029  24.78529  1.000 31.12116 ? 30  DT  D C7     1 
ATOM   939  C C6     . DT  B 2 14 ? 9.16308   -6.71089  23.43077  1.000 27.54852 ? 30  DT  D C6     1 
ATOM   940  H "H5'"  . DT  B 2 14 ? 9.94482   -10.40446 20.17939  1.000 37.82006 ? 30  DT  D "H5'"  1 
ATOM   941  H "H5''" . DT  B 2 14 ? 11.17245  -11.25111 20.69953  1.000 37.82006 ? 30  DT  D "H5''" 1 
ATOM   942  H "H4'"  . DT  B 2 14 ? 11.85073  -9.07514  20.22304  1.000 35.61446 ? 30  DT  D "H4'"  1 
ATOM   943  H "H3'"  . DT  B 2 14 ? 12.32597  -10.06069 22.74442  1.000 34.76295 ? 30  DT  D "H3'"  1 
ATOM   944  H "H2'"  . DT  B 2 14 ? 11.47909  -8.31876  23.83669  1.000 32.87609 ? 30  DT  D "H2'"  1 
ATOM   945  H "H2''" . DT  B 2 14 ? 12.79664  -7.57002  23.39183  1.000 32.87609 ? 30  DT  D "H2''" 1 
ATOM   946  H "H1'"  . DT  B 2 14 ? 11.84153  -6.69120  21.57704  1.000 32.62316 ? 30  DT  D "H1'"  1 
ATOM   947  H H3     . DT  B 2 14 ? 9.29568   -3.31414  22.48660  1.000 31.65670 ? 30  DT  D H3     1 
ATOM   948  H H71    . DT  B 2 14 ? 6.66881   -7.18976  24.34284  1.000 37.34539 ? 30  DT  D H71    1 
ATOM   949  H H72    . DT  B 2 14 ? 7.48235   -6.72939  25.62726  1.000 37.34539 ? 30  DT  D H72    1 
ATOM   950  H H73    . DT  B 2 14 ? 6.44985   -5.73512  24.94250  1.000 37.34539 ? 30  DT  D H73    1 
ATOM   951  H H6     . DT  B 2 14 ? 9.13368   -7.61670  23.63944  1.000 33.05822 ? 30  DT  D H6     1 
ATOM   952  P P      . DA  B 2 15 ? 15.03463  -9.28966  22.52045  1.000 29.25828 ? 31  DA  D P      1 
ATOM   953  O OP1    . DA  B 2 15 ? 16.05491  -9.89334  21.61984  1.000 33.18610 ? 31  DA  D OP1    1 
ATOM   954  O OP2    . DA  B 2 15 ? 14.68891  -9.87670  23.83202  1.000 28.34716 ? 31  DA  D OP2    1 
ATOM   955  O "O5'"  . DA  B 2 15 ? 15.41851  -7.77562  22.79686  1.000 27.28543 ? 31  DA  D "O5'"  1 
ATOM   956  C "C5'"  . DA  B 2 15 ? 15.59777  -6.90566  21.71846  1.000 28.84883 ? 31  DA  D "C5'"  1 
ATOM   957  C "C4'"  . DA  B 2 15 ? 15.76557  -5.49382  22.21361  1.000 25.51294 ? 31  DA  D "C4'"  1 
ATOM   958  O "O4'"  . DA  B 2 15 ? 14.48278  -4.98093  22.65151  1.000 24.59131 ? 31  DA  D "O4'"  1 
ATOM   959  C "C3'"  . DA  B 2 15 ? 16.69970  -5.32527  23.41635  1.000 26.17531 ? 31  DA  D "C3'"  1 
ATOM   960  O "O3'"  . DA  B 2 15 ? 17.52256  -4.21076  23.19508  1.000 31.75334 ? 31  DA  D "O3'"  1 
ATOM   961  C "C2'"  . DA  B 2 15 ? 15.72135  -5.07337  24.57207  1.000 24.02166 ? 31  DA  D "C2'"  1 
ATOM   962  C "C1'"  . DA  B 2 15 ? 14.70526  -4.24765  23.82961  1.000 22.45115 ? 31  DA  D "C1'"  1 
ATOM   963  N N9     . DA  B 2 15 ? 13.42359  -3.98934  24.47629  1.000 21.69138 ? 31  DA  D N9     1 
ATOM   964  C C8     . DA  B 2 15 ? 12.60545  -4.86759  25.12887  1.000 21.36785 ? 31  DA  D C8     1 
ATOM   965  N N7     . DA  B 2 15 ? 11.48178  -4.31764  25.56554  1.000 20.31877 ? 31  DA  D N7     1 
ATOM   966  C C5     . DA  B 2 15 ? 11.56540  -2.99959  25.14124  1.000 20.51661 ? 31  DA  D C5     1 
ATOM   967  C C6     . DA  B 2 15 ? 10.70321  -1.88815  25.27975  1.000 20.51098 ? 31  DA  D C6     1 
ATOM   968  N N6     . DA  B 2 15 ? 9.51628   -1.94450  25.89309  1.000 21.77920 ? 31  DA  D N6     1 
ATOM   969  N N1     . DA  B 2 15 ? 11.10476  -0.70818  24.73890  1.000 22.69596 ? 31  DA  D N1     1 
ATOM   970  C C2     . DA  B 2 15 ? 12.28188  -0.65593  24.11332  1.000 22.82610 ? 31  DA  D C2     1 
ATOM   971  N N3     . DA  B 2 15 ? 13.17529  -1.62772  23.91941  1.000 23.02018 ? 31  DA  D N3     1 
ATOM   972  C C4     . DA  B 2 15 ? 12.75695  -2.78180  24.47055  1.000 21.33613 ? 31  DA  D C4     1 
ATOM   973  H "H5'"  . DA  B 2 15 ? 14.82494  -6.95279  21.13416  1.000 34.61860 ? 31  DA  D "H5'"  1 
ATOM   974  H "H5''" . DA  B 2 15 ? 16.38717  -7.16851  21.21982  1.000 34.61860 ? 31  DA  D "H5''" 1 
ATOM   975  H "H4'"  . DA  B 2 15 ? 16.09615  -4.94720  21.48366  1.000 30.61553 ? 31  DA  D "H4'"  1 
ATOM   976  H "H3'"  . DA  B 2 15 ? 17.21685  -6.12960  23.57917  1.000 31.41037 ? 31  DA  D "H3'"  1 
ATOM   977  H "H2'"  . DA  B 2 15 ? 15.34314  -5.89633  24.91934  1.000 28.82599 ? 31  DA  D "H2'"  1 
ATOM   978  H "H2''" . DA  B 2 15 ? 16.13213  -4.58240  25.30085  1.000 28.82599 ? 31  DA  D "H2''" 1 
ATOM   979  H "H1'"  . DA  B 2 15 ? 15.08561  -3.37127  23.66173  1.000 26.94138 ? 31  DA  D "H1'"  1 
ATOM   980  H H8     . DA  B 2 15 ? 12.81672  -5.76453  25.25444  1.000 25.64143 ? 31  DA  D H8     1 
ATOM   981  H H61    . DA  B 2 15 ? 9.02258   -1.24188  25.93973  1.000 26.13504 ? 31  DA  D H61    1 
ATOM   982  H H62    . DA  B 2 15 ? 9.24665   -2.68337  26.24091  1.000 26.13504 ? 31  DA  D H62    1 
ATOM   983  H H2     . DA  B 2 15 ? 12.51204  0.17436   23.76326  1.000 27.39133 ? 31  DA  D H2     1 
ATOM   984  P P      . DT  B 2 16 ? 19.09708  -4.36184  22.99423  1.000 38.93027 ? 32  DT  D P      1 
ATOM   985  O OP1    . DT  B 2 16 ? 19.33969  -5.37818  21.94905  1.000 42.24981 ? 32  DT  D OP1    1 
ATOM   986  O OP2    . DT  B 2 16 ? 19.64548  -4.57600  24.35324  1.000 43.34775 ? 32  DT  D OP2    1 
ATOM   987  O "O5'"  . DT  B 2 16 ? 19.53294  -2.91797  22.46654  1.000 42.81371 ? 32  DT  D "O5'"  1 
ATOM   988  N N      . LYS C 3 5  ? 1.74112   6.50065   -10.90752 1.000 46.45016 ? 169 LYS F N      1 
ATOM   989  C CA     . LYS C 3 5  ? 2.34592   7.01737   -9.68515  1.000 44.18873 ? 169 LYS F CA     1 
ATOM   990  C C      . LYS C 3 5  ? 3.61713   6.25637   -9.33534  1.000 39.66218 ? 169 LYS F C      1 
ATOM   991  O O      . LYS C 3 5  ? 3.72288   5.04545   -9.52976  1.000 38.42482 ? 169 LYS F O      1 
ATOM   992  C CB     . LYS C 3 5  ? 1.37294   6.93022   -8.50819  1.000 46.76230 ? 169 LYS F CB     1 
ATOM   993  H HA     . LYS C 3 5  ? 2.56823   7.95023   -9.83090  1.000 53.02648 ? 169 LYS F HA     1 
ATOM   994  N N      . ILE C 3 6  ? 4.58648   6.98849   -8.79527  1.000 36.60123 ? 170 ILE F N      1 
ATOM   995  C CA     . ILE C 3 6  ? 5.85672   6.38089   -8.44468  1.000 34.56889 ? 170 ILE F CA     1 
ATOM   996  C C      . ILE C 3 6  ? 5.65686   5.31264   -7.36616  1.000 27.27980 ? 170 ILE F C      1 
ATOM   997  O O      . ILE C 3 6  ? 4.78538   5.42186   -6.48774  1.000 28.74766 ? 170 ILE F O      1 
ATOM   998  C CB     . ILE C 3 6  ? 6.82669   7.48815   -7.99578  1.000 41.28056 ? 170 ILE F CB     1 
ATOM   999  C CG1    . ILE C 3 6  ? 8.24684   6.94980   -7.84081  1.000 43.35539 ? 170 ILE F CG1    1 
ATOM   1000 C CG2    . ILE C 3 6  ? 6.36060   8.11913   -6.69781  1.000 44.75426 ? 170 ILE F CG2    1 
ATOM   1001 C CD1    . ILE C 3 6  ? 9.28269   8.04065   -7.65071  1.000 45.81448 ? 170 ILE F CD1    1 
ATOM   1002 H H      . ILE C 3 6  ? 4.53193   7.82962   -8.62457  1.000 43.92148 ? 170 ILE F H      1 
ATOM   1003 H HA     . ILE C 3 6  ? 6.23618   5.92402   -9.21162  1.000 41.48267 ? 170 ILE F HA     1 
ATOM   1004 H HB     . ILE C 3 6  ? 6.83313   8.16695   -8.68866  1.000 49.53668 ? 170 ILE F HB     1 
ATOM   1005 H HG12   . ILE C 3 6  ? 8.27941   6.36901   -7.06459  1.000 52.02647 ? 170 ILE F HG12   1 
ATOM   1006 H HG13   . ILE C 3 6  ? 8.48217   6.45080   -8.63863  1.000 52.02647 ? 170 ILE F HG13   1 
ATOM   1007 H HG21   . ILE C 3 6  ? 6.91865   8.88804   -6.50222  1.000 53.70511 ? 170 ILE F HG21   1 
ATOM   1008 H HG22   . ILE C 3 6  ? 5.43658   8.39744   -6.79592  1.000 53.70511 ? 170 ILE F HG22   1 
ATOM   1009 H HG23   . ILE C 3 6  ? 6.43542   7.46609   -5.98449  1.000 53.70511 ? 170 ILE F HG23   1 
ATOM   1010 H HD11   . ILE C 3 6  ? 10.16798  7.64679   -7.69563  1.000 54.97738 ? 170 ILE F HD11   1 
ATOM   1011 H HD12   . ILE C 3 6  ? 9.17843   8.70109   -8.35346  1.000 54.97738 ? 170 ILE F HD12   1 
ATOM   1012 H HD13   . ILE C 3 6  ? 9.14888   8.45568   -6.78425  1.000 54.97738 ? 170 ILE F HD13   1 
ATOM   1013 N N      . ARG C 3 7  ? 6.46582   4.25929   -7.44458  1.000 23.02560 ? 171 ARG F N      1 
ATOM   1014 C CA     . ARG C 3 7  ? 6.48491   3.21680   -6.43092  1.000 20.99553 ? 171 ARG F CA     1 
ATOM   1015 C C      . ARG C 3 7  ? 7.42068   3.60692   -5.29768  1.000 18.91023 ? 171 ARG F C      1 
ATOM   1016 O O      . ARG C 3 7  ? 8.40393   4.32187   -5.49508  1.000 19.35235 ? 171 ARG F O      1 
ATOM   1017 C CB     . ARG C 3 7  ? 6.92475   1.87997   -7.02275  1.000 22.81104 ? 171 ARG F CB     1 
ATOM   1018 C CG     . ARG C 3 7  ? 5.92216   1.35600   -8.06143  1.000 27.83358 ? 171 ARG F CG     1 
ATOM   1019 C CD     . ARG C 3 7  ? 6.16667   -0.08369  -8.45370  1.000 31.68188 ? 171 ARG F CD     1 
ATOM   1020 N NE     . ARG C 3 7  ? 5.89259   -1.02554  -7.37703  1.000 31.13755 ? 171 ARG F NE     1 
ATOM   1021 C CZ     . ARG C 3 7  ? 5.91537   -2.34444  -7.51808  1.000 32.94947 ? 171 ARG F CZ     1 
ATOM   1022 N NH1    . ARG C 3 7  ? 6.20793   -2.90816  -8.67546  1.000 37.60824 ? 171 ARG F NH1    1 
ATOM   1023 N NH2    . ARG C 3 7  ? 5.62679   -3.11629  -6.47286  1.000 34.47126 ? 171 ARG F NH2    1 
ATOM   1024 H H      . ARG C 3 7  ? 7.02139   4.12607   -8.08738  1.000 27.63072 ? 171 ARG F H      1 
ATOM   1025 H HA     . ARG C 3 7  ? 5.59030   3.10322   -6.07360  1.000 25.19463 ? 171 ARG F HA     1 
ATOM   1026 H HB2    . ARG C 3 7  ? 7.78400   1.99144   -7.45882  1.000 27.37325 ? 171 ARG F HB2    1 
ATOM   1027 H HB3    . ARG C 3 7  ? 6.99626   1.22431   -6.31148  1.000 27.37325 ? 171 ARG F HB3    1 
ATOM   1028 H HG2    . ARG C 3 7  ? 5.02697   1.41590   -7.69273  1.000 33.40030 ? 171 ARG F HG2    1 
ATOM   1029 H HG3    . ARG C 3 7  ? 5.98767   1.89797   -8.86323  1.000 33.40030 ? 171 ARG F HG3    1 
ATOM   1030 H HD2    . ARG C 3 7  ? 5.58991   -0.30868  -9.20044  1.000 38.01826 ? 171 ARG F HD2    1 
ATOM   1031 H HD3    . ARG C 3 7  ? 7.09654   -0.18644  -8.70998  1.000 38.01826 ? 171 ARG F HD3    1 
ATOM   1032 H HE     . ARG C 3 7  ? 5.70412   -0.70655  -6.60093  1.000 37.36506 ? 171 ARG F HE     1 
ATOM   1033 H HH11   . ARG C 3 7  ? 6.38912   -2.41834  -9.35872  1.000 45.12989 ? 171 ARG F HH11   1 
ATOM   1034 H HH12   . ARG C 3 7  ? 6.21732   -3.76520  -8.74614  1.000 45.12989 ? 171 ARG F HH12   1 
ATOM   1035 H HH21   . ARG C 3 7  ? 5.42829   -2.75895  -5.71622  1.000 41.36551 ? 171 ARG F HH21   1 
ATOM   1036 H HH22   . ARG C 3 7  ? 5.63882   -3.97236  -6.55414  1.000 41.36551 ? 171 ARG F HH22   1 
ATOM   1037 N N      . LEU C 3 8  ? 7.11365   3.10916   -4.09952  1.000 17.72404 ? 172 LEU F N      1 
ATOM   1038 C CA     . LEU C 3 8  ? 7.86124   3.53652   -2.92459  1.000 17.07848 ? 172 LEU F CA     1 
ATOM   1039 C C      . LEU C 3 8  ? 9.34628   3.23601   -3.08224  1.000 17.01307 ? 172 LEU F C      1 
ATOM   1040 O O      . LEU C 3 8  ? 10.19507  4.05273   -2.71069  1.000 17.12873 ? 172 LEU F O      1 
ATOM   1041 C CB     . LEU C 3 8  ? 7.29297   2.86680   -1.68214  1.000 16.53244 ? 172 LEU F CB     1 
ATOM   1042 C CG     . LEU C 3 8  ? 8.05654   3.03958   -0.36206  1.000 16.14729 ? 172 LEU F CG     1 
ATOM   1043 C CD1    . LEU C 3 8  ? 8.24726   4.49305   -0.00309  1.000 17.13632 ? 172 LEU F CD1    1 
ATOM   1044 C CD2    . LEU C 3 8  ? 7.36657   2.27393   0.77472   1.000 17.73635 ? 172 LEU F CD2    1 
ATOM   1045 H H      . LEU C 3 8  ? 6.49111   2.53617   -3.94550  1.000 21.26885 ? 172 LEU F H      1 
ATOM   1046 H HA     . LEU C 3 8  ? 7.76587   4.49542   -2.81361  1.000 20.49418 ? 172 LEU F HA     1 
ATOM   1047 H HB2    . LEU C 3 8  ? 6.40157   3.22092   -1.53752  1.000 19.83893 ? 172 LEU F HB2    1 
ATOM   1048 H HB3    . LEU C 3 8  ? 7.24715   1.91352   -1.85551  1.000 19.83893 ? 172 LEU F HB3    1 
ATOM   1049 H HG     . LEU C 3 8  ? 8.94290   2.66357   -0.47991  1.000 19.37675 ? 172 LEU F HG     1 
ATOM   1050 H HD11   . LEU C 3 8  ? 8.80454   4.55231   0.78863   1.000 20.56358 ? 172 LEU F HD11   1 
ATOM   1051 H HD12   . LEU C 3 8  ? 8.67659   4.94777   -0.74458  1.000 20.56358 ? 172 LEU F HD12   1 
ATOM   1052 H HD13   . LEU C 3 8  ? 7.38037   4.89147   0.17202   1.000 20.56358 ? 172 LEU F HD13   1 
ATOM   1053 H HD21   . LEU C 3 8  ? 7.89729   2.36126   1.58194   1.000 21.28362 ? 172 LEU F HD21   1 
ATOM   1054 H HD22   . LEU C 3 8  ? 6.48336   2.64875   0.91737   1.000 21.28362 ? 172 LEU F HD22   1 
ATOM   1055 H HD23   . LEU C 3 8  ? 7.29305   1.33906   0.52672   1.000 21.28362 ? 172 LEU F HD23   1 
ATOM   1056 N N      . TYR C 3 9  ? 9.69828   2.05897   -3.60342  1.000 17.64388 ? 173 TYR F N      1 
ATOM   1057 C CA     . TYR C 3 9  ? 11.12666  1.76067   -3.68398  1.000 17.86661 ? 173 TYR F CA     1 
ATOM   1058 C C      . TYR C 3 9  ? 11.82630  2.73899   -4.61047  1.000 17.08196 ? 173 TYR F C      1 
ATOM   1059 O O      . TYR C 3 9  ? 12.99798  3.06649   -4.39266  1.000 18.41974 ? 173 TYR F O      1 
ATOM   1060 C CB     . TYR C 3 9  ? 11.40625  0.30538   -4.08516  1.000 20.14909 ? 173 TYR F CB     1 
ATOM   1061 C CG     . TYR C 3 9  ? 11.02867  -0.07087  -5.50210  1.000 20.87493 ? 173 TYR F CG     1 
ATOM   1062 C CD1    . TYR C 3 9  ? 11.86609  0.24141   -6.55483  1.000 22.53136 ? 173 TYR F CD1    1 
ATOM   1063 C CD2    . TYR C 3 9  ? 9.85786   -0.75348  -5.78164  1.000 22.33528 ? 173 TYR F CD2    1 
ATOM   1064 C CE1    . TYR C 3 9  ? 11.54781  -0.10153  -7.84853  1.000 25.89203 ? 173 TYR F CE1    1 
ATOM   1065 C CE2    . TYR C 3 9  ? 9.53354   -1.10338  -7.07421  1.000 24.64994 ? 173 TYR F CE2    1 
ATOM   1066 C CZ     . TYR C 3 9  ? 10.38605  -0.77580  -8.10062  1.000 26.11802 ? 173 TYR F CZ     1 
ATOM   1067 O OH     . TYR C 3 9  ? 10.06989  -1.11540  -9.39674  1.000 31.25909 ? 173 TYR F OH     1 
ATOM   1068 H H      . TYR C 3 9  ? 9.16313   1.45404   -3.89882  1.000 21.17266 ? 173 TYR F H      1 
ATOM   1069 H HA     . TYR C 3 9  ? 11.50295  1.84965   -2.79438  1.000 21.43993 ? 173 TYR F HA     1 
ATOM   1070 H HB2    . TYR C 3 9  ? 12.35714  0.14046   -3.98764  1.000 24.17891 ? 173 TYR F HB2    1 
ATOM   1071 H HB3    . TYR C 3 9  ? 10.90612  -0.27534  -3.49057  1.000 24.17891 ? 173 TYR F HB3    1 
ATOM   1072 H HD1    . TYR C 3 9  ? 12.66145  0.69276   -6.38578  1.000 27.03763 ? 173 TYR F HD1    1 
ATOM   1073 H HD2    . TYR C 3 9  ? 9.28182   -0.97923  -5.08729  1.000 26.80233 ? 173 TYR F HD2    1 
ATOM   1074 H HE1    . TYR C 3 9  ? 12.11926  0.12392   -8.54676  1.000 31.07044 ? 173 TYR F HE1    1 
ATOM   1075 H HE2    . TYR C 3 9  ? 8.74210   -1.55869  -7.25088  1.000 29.57993 ? 173 TYR F HE2    1 
ATOM   1076 H HH     . TYR C 3 9  ? 10.67049  -0.84652  -9.91884  1.000 37.51090 ? 173 TYR F HH     1 
ATOM   1077 N N      . GLN C 3 10 ? 11.12698  3.20602   -5.64950  1.000 19.45492 ? 174 GLN F N      1 
ATOM   1078 C CA     . GLN C 3 10 ? 11.73391  4.14446   -6.58720  1.000 20.35562 ? 174 GLN F CA     1 
ATOM   1079 C C      . GLN C 3 10 ? 11.85863  5.53586   -5.98107  1.000 20.22014 ? 174 GLN F C      1 
ATOM   1080 O O      . GLN C 3 10 ? 12.86681  6.22859   -6.19376  1.000 20.45757 ? 174 GLN F O      1 
ATOM   1081 C CB     . GLN C 3 10 ? 10.91963  4.19136   -7.87437  1.000 24.62487 ? 174 GLN F CB     1 
ATOM   1082 C CG     . GLN C 3 10 ? 11.62215  4.96208   -8.98378  1.000 30.01722 ? 174 GLN F CG     1 
ATOM   1083 C CD     . GLN C 3 10 ? 12.85796  4.25721   -9.51548  1.000 35.73611 ? 174 GLN F CD     1 
ATOM   1084 O OE1    . GLN C 3 10 ? 12.81544  3.07340   -9.85838  1.000 37.30635 ? 174 GLN F OE1    1 
ATOM   1085 N NE2    . GLN C 3 10 ? 13.97622  4.98024   -9.56585  1.000 39.37676 ? 174 GLN F NE2    1 
ATOM   1086 H H      . GLN C 3 10 ? 10.31231  2.99690   -5.82888  1.000 23.34591 ? 174 GLN F H      1 
ATOM   1087 H HA     . GLN C 3 10 ? 12.62690  3.83435   -6.80467  1.000 24.42675 ? 174 GLN F HA     1 
ATOM   1088 H HB2    . GLN C 3 10 ? 10.76869  3.28536   -8.18624  1.000 29.54984 ? 174 GLN F HB2    1 
ATOM   1089 H HB3    . GLN C 3 10 ? 10.07125  4.62655   -7.69616  1.000 29.54984 ? 174 GLN F HB3    1 
ATOM   1090 H HG2    . GLN C 3 10 ? 11.00554  5.08006   -9.72322  1.000 36.02067 ? 174 GLN F HG2    1 
ATOM   1091 H HG3    . GLN C 3 10 ? 11.89726  5.82641   -8.64007  1.000 36.02067 ? 174 GLN F HG3    1 
ATOM   1092 H HE21   . GLN C 3 10 ? 13.97054  5.79972   -9.30504  1.000 47.25211 ? 174 GLN F HE21   1 
ATOM   1093 H HE22   . GLN C 3 10 ? 14.70358  4.62738   -9.85917  1.000 47.25211 ? 174 GLN F HE22   1 
ATOM   1094 N N      . PHE C 3 11 ? 10.86577  5.94307   -5.18849  1.000 19.33342 ? 175 PHE F N      1 
ATOM   1095 C CA     . PHE C 3 11 ? 10.95229  7.20234   -4.45610  1.000 19.59435 ? 175 PHE F CA     1 
ATOM   1096 C C      . PHE C 3 11 ? 12.19149  7.22541   -3.57084  1.000 19.34158 ? 175 PHE F C      1 
ATOM   1097 O O      . PHE C 3 11 ? 12.94664  8.21005   -3.55139  1.000 19.58190 ? 175 PHE F O      1 
ATOM   1098 C CB     . PHE C 3 11 ? 9.68277   7.33920   -3.62029  1.000 19.60564 ? 175 PHE F CB     1 
ATOM   1099 C CG     . PHE C 3 11 ? 9.71509   8.43261   -2.58259  1.000 20.05191 ? 175 PHE F CG     1 
ATOM   1100 C CD1    . PHE C 3 11 ? 9.43951   9.75496   -2.90782  1.000 21.41533 ? 175 PHE F CD1    1 
ATOM   1101 C CD2    . PHE C 3 11 ? 9.95568   8.11094   -1.24992  1.000 19.53153 ? 175 PHE F CD2    1 
ATOM   1102 C CE1    . PHE C 3 11 ? 9.44074   10.73542  -1.91991  1.000 22.15844 ? 175 PHE F CE1    1 
ATOM   1103 C CE2    . PHE C 3 11 ? 9.96898   9.08404   -0.27098  1.000 21.52207 ? 175 PHE F CE2    1 
ATOM   1104 C CZ     . PHE C 3 11 ? 9.69702   10.39526  -0.60266  1.000 23.36572 ? 175 PHE F CZ     1 
ATOM   1105 H H      . PHE C 3 11 ? 10.13451  5.50943   -5.05881  1.000 23.20010 ? 175 PHE F H      1 
ATOM   1106 H HA     . PHE C 3 11 ? 11.01838  7.95213   -5.06795  1.000 23.51322 ? 175 PHE F HA     1 
ATOM   1107 H HB2    . PHE C 3 11 ? 8.94148   7.52710   -4.21703  1.000 23.52677 ? 175 PHE F HB2    1 
ATOM   1108 H HB3    . PHE C 3 11 ? 9.53012   6.50184   -3.15506  1.000 23.52677 ? 175 PHE F HB3    1 
ATOM   1109 H HD1    . PHE C 3 11 ? 9.25345   9.98595   -3.78926  1.000 25.69840 ? 175 PHE F HD1    1 
ATOM   1110 H HD2    . PHE C 3 11 ? 10.11023  7.22452   -1.01482  1.000 23.43784 ? 175 PHE F HD2    1 
ATOM   1111 H HE1    . PHE C 3 11 ? 9.26898   11.62120  -2.14527  1.000 26.59013 ? 175 PHE F HE1    1 
ATOM   1112 H HE2    . PHE C 3 11 ? 10.16082  8.85628   0.61006   1.000 25.82648 ? 175 PHE F HE2    1 
ATOM   1113 H HZ     . PHE C 3 11 ? 9.68587   11.04987  0.05785   1.000 28.03887 ? 175 PHE F HZ     1 
ATOM   1114 N N      . LEU C 3 12 ? 12.43629  6.12885   -2.84949  1.000 17.97137 ? 176 LEU F N      1 
ATOM   1115 C CA     . LEU C 3 12 ? 13.59133  6.07457   -1.96012  1.000 17.92552 ? 176 LEU F CA     1 
ATOM   1116 C C      . LEU C 3 12 ? 14.90122  6.03887   -2.74081  1.000 18.23641 ? 176 LEU F C      1 
ATOM   1117 O O      . LEU C 3 12 ? 15.86599  6.71953   -2.37163  1.000 19.19221 ? 176 LEU F O      1 
ATOM   1118 C CB     . LEU C 3 12 ? 13.48264  4.85842   -1.04390  1.000 17.49626 ? 176 LEU F CB     1 
ATOM   1119 C CG     . LEU C 3 12 ? 12.26780  4.84135   -0.11159  1.000 17.14404 ? 176 LEU F CG     1 
ATOM   1120 C CD1    . LEU C 3 12 ? 12.17455  3.49664   0.59884   1.000 17.83532 ? 176 LEU F CD1    1 
ATOM   1121 C CD2    . LEU C 3 12 ? 12.29952  5.97611   0.90052   1.000 17.42115 ? 176 LEU F CD2    1 
ATOM   1122 H H      . LEU C 3 12 ? 11.95590  5.41558   -2.85803  1.000 21.56564 ? 176 LEU F H      1 
ATOM   1123 H HA     . LEU C 3 12 ? 13.59656  6.87330   -1.40976  1.000 21.51063 ? 176 LEU F HA     1 
ATOM   1124 H HB2    . LEU C 3 12 ? 13.43344  4.06360   -1.59774  1.000 20.99551 ? 176 LEU F HB2    1 
ATOM   1125 H HB3    . LEU C 3 12 ? 14.27568  4.82567   -0.48630  1.000 20.99551 ? 176 LEU F HB3    1 
ATOM   1126 H HG     . LEU C 3 12 ? 11.47265  4.97212   -0.65155  1.000 20.57285 ? 176 LEU F HG     1 
ATOM   1127 H HD11   . LEU C 3 12 ? 11.37308  3.48296   1.14506   1.000 21.40238 ? 176 LEU F HD11   1 
ATOM   1128 H HD12   . LEU C 3 12 ? 12.13434  2.79075   -0.06524  1.000 21.40238 ? 176 LEU F HD12   1 
ATOM   1129 H HD13   . LEU C 3 12 ? 12.95824  3.38010   1.15843   1.000 21.40238 ? 176 LEU F HD13   1 
ATOM   1130 H HD21   . LEU C 3 12 ? 11.62064  5.81692   1.57482   1.000 20.90538 ? 176 LEU F HD21   1 
ATOM   1131 H HD22   . LEU C 3 12 ? 13.17629  6.00570   1.31440   1.000 20.90538 ? 176 LEU F HD22   1 
ATOM   1132 H HD23   . LEU C 3 12 ? 12.12140  6.81258   0.44282   1.000 20.90538 ? 176 LEU F HD23   1 
ATOM   1133 N N      . LEU C 3 13 ? 14.96862  5.22847   -3.79768  1.000 18.47297 ? 177 LEU F N      1 
ATOM   1134 C CA     . LEU C 3 13 ? 16.17825  5.17131   -4.60916  1.000 19.28534 ? 177 LEU F CA     1 
ATOM   1135 C C      . LEU C 3 13 ? 16.48315  6.53814   -5.21457  1.000 20.54526 ? 177 LEU F C      1 
ATOM   1136 O O      . LEU C 3 13 ? 17.64154  6.96208   -5.26217  1.000 22.16495 ? 177 LEU F O      1 
ATOM   1137 C CB     . LEU C 3 13 ? 16.01501  4.10843   -5.70436  1.000 21.84481 ? 177 LEU F CB     1 
ATOM   1138 C CG     . LEU C 3 13 ? 17.24643  3.82753   -6.57259  1.000 24.54626 ? 177 LEU F CG     1 
ATOM   1139 C CD1    . LEU C 3 13 ? 18.44981  3.41009   -5.73457  1.000 24.68795 ? 177 LEU F CD1    1 
ATOM   1140 C CD2    . LEU C 3 13 ? 16.95102  2.75985   -7.60962  1.000 25.64985 ? 177 LEU F CD2    1 
ATOM   1141 H H      . LEU C 3 13 ? 14.33578  4.70925   -4.06134  1.000 22.16757 ? 177 LEU F H      1 
ATOM   1142 H HA     . LEU C 3 13 ? 16.93148  4.91336   -4.05507  1.000 23.14241 ? 177 LEU F HA     1 
ATOM   1143 H HB2    . LEU C 3 13 ? 15.77015  3.27241   -5.27774  1.000 26.21377 ? 177 LEU F HB2    1 
ATOM   1144 H HB3    . LEU C 3 13 ? 15.30593  4.39707   -6.30001  1.000 26.21377 ? 177 LEU F HB3    1 
ATOM   1145 H HG     . LEU C 3 13 ? 17.47253  4.65284   -7.02935  1.000 29.45552 ? 177 LEU F HG     1 
ATOM   1146 H HD11   . LEU C 3 13 ? 19.17569  3.15948   -6.32718  1.000 29.62554 ? 177 LEU F HD11   1 
ATOM   1147 H HD12   . LEU C 3 13 ? 18.72056  4.15629   -5.17709  1.000 29.62554 ? 177 LEU F HD12   1 
ATOM   1148 H HD13   . LEU C 3 13 ? 18.20095  2.65512   -5.17870  1.000 29.62554 ? 177 LEU F HD13   1 
ATOM   1149 H HD21   . LEU C 3 13 ? 17.75575  2.58683   -8.12282  1.000 30.77982 ? 177 LEU F HD21   1 
ATOM   1150 H HD22   . LEU C 3 13 ? 16.66675  1.95026   -7.15723  1.000 30.77982 ? 177 LEU F HD22   1 
ATOM   1151 H HD23   . LEU C 3 13 ? 16.24613  3.07586   -8.19627  1.000 30.77982 ? 177 LEU F HD23   1 
ATOM   1152 N N      . ASP C 3 14 ? 15.44840  7.24503   -5.67832  1.000 20.59389 ? 178 ASP F N      1 
ATOM   1153 C CA     . ASP C 3 14 ? 15.64782  8.57072   -6.25878  1.000 23.09599 ? 178 ASP F CA     1 
ATOM   1154 C C      . ASP C 3 14 ? 16.17823  9.55132   -5.21832  1.000 22.88855 ? 178 ASP F C      1 
ATOM   1155 O O      . ASP C 3 14 ? 17.03928  10.39015  -5.52091  1.000 23.97200 ? 178 ASP F O      1 
ATOM   1156 C CB     . ASP C 3 14 ? 14.32367  9.07891   -6.84682  1.000 26.08069 ? 178 ASP F CB     1 
ATOM   1157 C CG     . ASP C 3 14 ? 13.89970  8.32734   -8.10415  1.000 32.70371 ? 178 ASP F CG     1 
ATOM   1158 O OD1    . ASP C 3 14 ? 14.68245  7.50246   -8.61588  1.000 32.57773 ? 178 ASP F OD1    1 
ATOM   1159 O OD2    . ASP C 3 14 ? 12.75844  8.55619   -8.56983  1.000 39.73342 ? 178 ASP F OD2    1 
ATOM   1160 H H      . ASP C 3 14 ? 14.62989  6.98133   -5.66813  1.000 24.71267 ? 178 ASP F H      1 
ATOM   1161 H HA     . ASP C 3 14 ? 16.29917  8.51012   -6.97500  1.000 27.71519 ? 178 ASP F HA     1 
ATOM   1162 H HB2    . ASP C 3 14 ? 13.62328  8.97141   -6.18440  1.000 31.29683 ? 178 ASP F HB2    1 
ATOM   1163 H HB3    . ASP C 3 14 ? 14.42089  10.01599  -7.07776  1.000 31.29683 ? 178 ASP F HB3    1 
ATOM   1164 N N      . LEU C 3 15 ? 15.65742  9.48390   -3.98755  1.000 21.18232 ? 179 LEU F N      1 
ATOM   1165 C CA     . LEU C 3 15 ? 16.16461  10.36924  -2.94323  1.000 22.09923 ? 179 LEU F CA     1 
ATOM   1166 C C      . LEU C 3 15 ? 17.63245  10.09955  -2.67503  1.000 22.45186 ? 179 LEU F C      1 
ATOM   1167 O O      . LEU C 3 15 ? 18.42517  11.03231  -2.49067  1.000 24.67269 ? 179 LEU F O      1 
ATOM   1168 C CB     . LEU C 3 15 ? 15.39091  10.16442  -1.64266  1.000 23.73876 ? 179 LEU F CB     1 
ATOM   1169 C CG     . LEU C 3 15 ? 14.05910  10.86993  -1.43494  1.000 26.74641 ? 179 LEU F CG     1 
ATOM   1170 C CD1    . LEU C 3 15 ? 13.49251  10.52509  -0.05806  1.000 27.09283 ? 179 LEU F CD1    1 
ATOM   1171 C CD2    . LEU C 3 15 ? 14.24570  12.36676  -1.57320  1.000 29.37383 ? 179 LEU F CD2    1 
ATOM   1172 H H      . LEU C 3 15 ? 15.02949  8.95012   -3.74183  1.000 25.41878 ? 179 LEU F H      1 
ATOM   1173 H HA     . LEU C 3 15 ? 16.04483  11.28439  -3.24166  1.000 26.51908 ? 179 LEU F HA     1 
ATOM   1174 H HB2    . LEU C 3 15 ? 15.20928  9.21491   -1.56305  1.000 28.48652 ? 179 LEU F HB2    1 
ATOM   1175 H HB3    . LEU C 3 15 ? 15.96638  10.45406  -0.91751  1.000 28.48652 ? 179 LEU F HB3    1 
ATOM   1176 H HG     . LEU C 3 15 ? 13.42309  10.57619  -2.10584  1.000 32.09569 ? 179 LEU F HG     1 
ATOM   1177 H HD11   . LEU C 3 15 ? 12.61669  10.93175  0.03393   1.000 32.51139 ? 179 LEU F HD11   1 
ATOM   1178 H HD12   . LEU C 3 15 ? 13.41954  9.56107   0.02101   1.000 32.51139 ? 179 LEU F HD12   1 
ATOM   1179 H HD13   . LEU C 3 15 ? 14.09007  10.86867  0.62442   1.000 32.51139 ? 179 LEU F HD13   1 
ATOM   1180 H HD21   . LEU C 3 15 ? 13.46677  12.81694  -1.21057  1.000 35.24859 ? 179 LEU F HD21   1 
ATOM   1181 H HD22   . LEU C 3 15 ? 15.03944  12.63265  -1.08313  1.000 35.24859 ? 179 LEU F HD22   1 
ATOM   1182 H HD23   . LEU C 3 15 ? 14.34760  12.58688  -2.51238  1.000 35.24859 ? 179 LEU F HD23   1 
ATOM   1183 N N      . LEU C 3 16 ? 18.00457  8.82101   -2.60618  1.000 20.93937 ? 180 LEU F N      1 
ATOM   1184 C CA     . LEU C 3 16 ? 19.39161  8.47145   -2.34017  1.000 21.28436 ? 180 LEU F CA     1 
ATOM   1185 C C      . LEU C 3 16 ? 20.30325  8.97751   -3.45131  1.000 24.50783 ? 180 LEU F C      1 
ATOM   1186 O O      . LEU C 3 16 ? 21.41606  9.44523   -3.18699  1.000 26.29297 ? 180 LEU F O      1 
ATOM   1187 C CB     . LEU C 3 16 ? 19.49020  6.95936   -2.16106  1.000 20.41246 ? 180 LEU F CB     1 
ATOM   1188 C CG     . LEU C 3 16 ? 19.03982  6.47689   -0.78337  1.000 19.02266 ? 180 LEU F CG     1 
ATOM   1189 C CD1    . LEU C 3 16 ? 18.73492  4.98885   -0.80295  1.000 20.56202 ? 180 LEU F CD1    1 
ATOM   1190 C CD2    . LEU C 3 16 ? 20.09984  6.79287   0.25945   1.000 21.21621 ? 180 LEU F CD2    1 
ATOM   1191 H H      . LEU C 3 16 ? 17.47858  8.14839   -2.70876  1.000 25.12724 ? 180 LEU F H      1 
ATOM   1192 H HA     . LEU C 3 16 ? 19.69472  8.88821   -1.51838  1.000 25.54123 ? 180 LEU F HA     1 
ATOM   1193 H HB2    . LEU C 3 16 ? 18.92892  6.52936   -2.82512  1.000 24.49495 ? 180 LEU F HB2    1 
ATOM   1194 H HB3    . LEU C 3 16 ? 20.41412  6.69039   -2.28320  1.000 24.49495 ? 180 LEU F HB3    1 
ATOM   1195 H HG     . LEU C 3 16 ? 18.22420  6.94164   -0.53908  1.000 22.82719 ? 180 LEU F HG     1 
ATOM   1196 H HD11   . LEU C 3 16 ? 18.43531  4.71626   0.07843   1.000 24.67443 ? 180 LEU F HD11   1 
ATOM   1197 H HD12   . LEU C 3 16 ? 18.03891  4.81767   -1.45653  1.000 24.67443 ? 180 LEU F HD12   1 
ATOM   1198 H HD13   . LEU C 3 16 ? 19.54038  4.50458   -1.04295  1.000 24.67443 ? 180 LEU F HD13   1 
ATOM   1199 H HD21   . LEU C 3 16 ? 19.81804  6.43339   1.11517   1.000 25.45945 ? 180 LEU F HD21   1 
ATOM   1200 H HD22   . LEU C 3 16 ? 20.93864  6.38692   -0.00982  1.000 25.45945 ? 180 LEU F HD22   1 
ATOM   1201 H HD23   . LEU C 3 16 ? 20.20344  7.75524   0.32289   1.000 25.45945 ? 180 LEU F HD23   1 
ATOM   1202 N N      . ARG C 3 17 ? 19.83857  8.91653   -4.69882  1.000 25.87870 ? 181 ARG F N      1 
ATOM   1203 C CA     . ARG C 3 17 ? 20.66070  9.38996   -5.80803  1.000 29.97204 ? 181 ARG F CA     1 
ATOM   1204 C C      . ARG C 3 17 ? 20.75470  10.90876  -5.81884  1.000 33.10380 ? 181 ARG F C      1 
ATOM   1205 O O      . ARG C 3 17 ? 21.80932  11.46623  -6.14347  1.000 37.34151 ? 181 ARG F O      1 
ATOM   1206 C CB     . ARG C 3 17 ? 20.08854  8.88190   -7.12643  1.000 32.26608 ? 181 ARG F CB     1 
ATOM   1207 C CG     . ARG C 3 17 ? 20.21529  7.39373   -7.28204  1.000 36.01324 ? 181 ARG F CG     1 
ATOM   1208 C CD     . ARG C 3 17 ? 19.82753  6.94812   -8.67014  1.000 40.81223 ? 181 ARG F CD     1 
ATOM   1209 N NE     . ARG C 3 17 ? 20.11264  5.53522   -8.87165  1.000 42.70004 ? 181 ARG F NE     1 
ATOM   1210 C CZ     . ARG C 3 17 ? 19.37833  4.71635   -9.60875  1.000 41.84223 ? 181 ARG F CZ     1 
ATOM   1211 N NH1    . ARG C 3 17 ? 18.23696  5.10789   -10.15250 1.000 38.81688 ? 181 ARG F NH1    1 
ATOM   1212 N NH2    . ARG C 3 17 ? 19.80987  3.47715   -9.82224  1.000 42.78916 ? 181 ARG F NH2    1 
ATOM   1213 H H      . ARG C 3 17 ? 19.06680  8.61181   -4.92492  1.000 31.05444 ? 181 ARG F H      1 
ATOM   1214 H HA     . ARG C 3 17 ? 21.55811  9.03575   -5.70757  1.000 35.96645 ? 181 ARG F HA     1 
ATOM   1215 H HB2    . ARG C 3 17 ? 19.14647  9.10891   -7.16964  1.000 38.71929 ? 181 ARG F HB2    1 
ATOM   1216 H HB3    . ARG C 3 17 ? 20.56497  9.30187   -7.85960  1.000 38.71929 ? 181 ARG F HB3    1 
ATOM   1217 H HG2    . ARG C 3 17 ? 21.13557  7.13130   -7.12353  1.000 43.21589 ? 181 ARG F HG2    1 
ATOM   1218 H HG3    . ARG C 3 17 ? 19.63040  6.95316   -6.64588  1.000 43.21589 ? 181 ARG F HG3    1 
ATOM   1219 H HD2    . ARG C 3 17 ? 18.87669  7.08968   -8.79961  1.000 48.97467 ? 181 ARG F HD2    1 
ATOM   1220 H HD3    . ARG C 3 17 ? 20.33091  7.45792   -9.32406  1.000 48.97467 ? 181 ARG F HD3    1 
ATOM   1221 H HE     . ARG C 3 17 ? 20.80768  5.20891   -8.48430  1.000 51.24005 ? 181 ARG F HE     1 
ATOM   1222 H HH11   . ARG C 3 17 ? 17.95594  5.91148   -10.03060 1.000 46.58025 ? 181 ARG F HH11   1 
ATOM   1223 H HH12   . ARG C 3 17 ? 17.77635  4.55871   -10.62772 1.000 46.58025 ? 181 ARG F HH12   1 
ATOM   1224 H HH21   . ARG C 3 17 ? 20.55641  3.21743   -9.48339  1.000 51.34699 ? 181 ARG F HH21   1 
ATOM   1225 H HH22   . ARG C 3 17 ? 19.34247  2.93524   -10.29919 1.000 51.34699 ? 181 ARG F HH22   1 
ATOM   1226 N N      . SER C 3 18 ? 19.66570  11.59432  -5.46659  1.000 33.54389 ? 182 SER F N      1 
ATOM   1227 C CA     . SER C 3 18 ? 19.64300  13.05223  -5.52784  1.000 35.83338 ? 182 SER F CA     1 
ATOM   1228 C C      . SER C 3 18 ? 20.31994  13.69501  -4.32153  1.000 37.08315 ? 182 SER F C      1 
ATOM   1229 O O      . SER C 3 18 ? 20.82595  14.82094  -4.43058  1.000 38.79324 ? 182 SER F O      1 
ATOM   1230 C CB     . SER C 3 18 ? 18.19669  13.54219  -5.63268  1.000 38.15404 ? 182 SER F CB     1 
ATOM   1231 O OG     . SER C 3 18 ? 17.52775  13.42230  -4.38619  1.000 37.85881 ? 182 SER F OG     1 
ATOM   1232 H H      . SER C 3 18 ? 18.93231  11.23996  -5.19060  1.000 40.25267 ? 182 SER F H      1 
ATOM   1233 H HA     . SER C 3 18 ? 20.12278  13.33631  -6.32157  1.000 43.00006 ? 182 SER F HA     1 
ATOM   1234 H HB2    . SER C 3 18 ? 18.19832  14.47429  -5.90117  1.000 45.78485 ? 182 SER F HB2    1 
ATOM   1235 H HB3    . SER C 3 18 ? 17.72984  13.00736  -6.29368  1.000 45.78485 ? 182 SER F HB3    1 
ATOM   1236 H HG     . SER C 3 18 ? 17.57452  12.63037  -4.11004  1.000 45.43057 ? 182 SER F HG     1 
ATOM   1237 N N      . GLY C 3 19 ? 20.33133  13.01396  -3.17448  1.000 38.48277 ? 183 GLY F N      1 
ATOM   1238 C CA     . GLY C 3 19 ? 20.88904  13.58217  -1.95850  1.000 38.03198 ? 183 GLY F CA     1 
ATOM   1239 C C      . GLY C 3 19 ? 20.01550  14.62624  -1.29571  1.000 39.23611 ? 183 GLY F C      1 
ATOM   1240 O O      . GLY C 3 19 ? 20.48322  15.33603  -0.40268  1.000 39.42434 ? 183 GLY F O      1 
ATOM   1241 H H      . GLY C 3 19 ? 20.01966  12.21812  -3.07908  1.000 46.17932 ? 183 GLY F H      1 
ATOM   1242 H HA2    . GLY C 3 19 ? 21.03592  12.86773  -1.31905  1.000 45.63837 ? 183 GLY F HA2    1 
ATOM   1243 H HA3    . GLY C 3 19 ? 21.74011  13.99690  -2.16968  1.000 45.63837 ? 183 GLY F HA3    1 
ATOM   1244 N N      . ASP C 3 20 ? 18.74131  14.72027  -1.68209  1.000 37.01916 ? 184 ASP F N      1 
ATOM   1245 C CA     . ASP C 3 20 ? 17.92848  15.86742  -1.28296  1.000 37.92359 ? 184 ASP F CA     1 
ATOM   1246 C C      . ASP C 3 20 ? 17.49188  15.82072  0.17629   0.695 35.81253 ? 184 ASP F C      1 
ATOM   1247 O O      . ASP C 3 20 ? 17.14290  16.86552  0.73637   1.000 40.09335 ? 184 ASP F O      1 
ATOM   1248 C CB     . ASP C 3 20 ? 16.69520  15.99119  -2.17494  1.000 40.59065 ? 184 ASP F CB     1 
ATOM   1249 C CG     . ASP C 3 20 ? 16.07722  17.37183  -2.11346  0.715 43.16567 ? 184 ASP F CG     1 
ATOM   1250 O OD1    . ASP C 3 20 ? 16.70275  18.32192  -2.62325  0.292 44.69207 ? 184 ASP F OD1    1 
ATOM   1251 O OD2    . ASP C 3 20 ? 14.97162  17.51503  -1.54938  0.560 43.47709 ? 184 ASP F OD2    1 
ATOM   1252 H H      . ASP C 3 20 ? 18.33072  14.14170  -2.16818  1.000 44.42300 ? 184 ASP F H      1 
ATOM   1253 H HA     . ASP C 3 20 ? 18.47259  16.66141  -1.40303  0.976 45.50831 ? 184 ASP F HA     1 
ATOM   1254 H HB2    . ASP C 3 20 ? 16.94904  15.81487  -3.09438  1.000 48.70878 ? 184 ASP F HB2    1 
ATOM   1255 H HB3    . ASP C 3 20 ? 16.02825  15.34891  -1.88590  1.000 48.70878 ? 184 ASP F HB3    1 
ATOM   1256 N N      . MET C 3 21 ? 17.46751  14.64658  0.79459   1.000 29.97840 ? 185 MET F N      1 
ATOM   1257 C CA     . MET C 3 21 ? 17.14022  14.49856  2.21140   1.000 27.39815 ? 185 MET F CA     1 
ATOM   1258 C C      . MET C 3 21 ? 18.23212  13.70239  2.91091   1.000 27.76603 ? 185 MET F C      1 
ATOM   1259 O O      . MET C 3 21 ? 17.97741  12.68642  3.56554   1.000 25.27569 ? 185 MET F O      1 
ATOM   1260 C CB     . MET C 3 21 ? 15.77976  13.83908  2.41271   1.000 26.84717 ? 185 MET F CB     1 
ATOM   1261 C CG     . MET C 3 21 ? 14.60725  14.59378  1.80439   1.000 28.83869 ? 185 MET F CG     1 
ATOM   1262 S SD     . MET C 3 21 ? 13.02167  13.97074  2.38173   1.000 28.09688 ? 185 MET F SD     1 
ATOM   1263 C CE     . MET C 3 21 ? 12.93725  14.67149  4.02749   1.000 26.89159 ? 185 MET F CE     1 
ATOM   1264 H H      . MET C 3 21 ? 17.64156  13.89990  0.40500   1.000 35.97408 ? 185 MET F H      1 
ATOM   1265 H HA     . MET C 3 21 ? 17.09384  15.38573  2.60086   1.000 32.87778 ? 185 MET F HA     1 
ATOM   1266 H HB2    . MET C 3 21 ? 15.80177  12.95843  2.00668   1.000 32.21661 ? 185 MET F HB2    1 
ATOM   1267 H HB3    . MET C 3 21 ? 15.61365  13.76120  3.36520   1.000 32.21661 ? 185 MET F HB3    1 
ATOM   1268 H HG2    . MET C 3 21 ? 14.67081  15.53032  2.04881   1.000 34.60642 ? 185 MET F HG2    1 
ATOM   1269 H HG3    . MET C 3 21 ? 14.63522  14.50013  0.83933   1.000 34.60642 ? 185 MET F HG3    1 
ATOM   1270 H HE1    . MET C 3 21 ? 12.08292  14.44158  4.42519   1.000 32.26991 ? 185 MET F HE1    1 
ATOM   1271 H HE2    . MET C 3 21 ? 13.65985  14.30807  4.56292   1.000 32.26991 ? 185 MET F HE2    1 
ATOM   1272 H HE3    . MET C 3 21 ? 13.02432  15.63556  3.96508   1.000 32.26991 ? 185 MET F HE3    1 
ATOM   1273 N N      . LYS C 3 22 ? 19.47860  14.17416  2.76791   1.000 30.02601 ? 186 LYS F N      1 
ATOM   1274 C CA     . LYS C 3 22 ? 20.64299  13.44071  3.26445   1.000 32.09613 ? 186 LYS F CA     1 
ATOM   1275 C C      . LYS C 3 22 ? 20.61914  13.24426  4.77070   1.000 30.05931 ? 186 LYS F C      1 
ATOM   1276 O O      . LYS C 3 22 ? 21.31401  12.35507  5.27873   1.000 29.41732 ? 186 LYS F O      1 
ATOM   1277 C CB     . LYS C 3 22 ? 21.95137  14.17580  2.93466   1.000 40.01782 ? 186 LYS F CB     1 
ATOM   1278 C CG     . LYS C 3 22 ? 22.36933  14.15330  1.47522   1.000 48.66226 ? 186 LYS F CG     1 
ATOM   1279 C CD     . LYS C 3 22 ? 23.89034  14.25476  1.30364   1.000 55.57474 ? 186 LYS F CD     1 
ATOM   1280 C CE     . LYS C 3 22 ? 24.52623  12.90117  0.96853   1.000 61.17120 ? 186 LYS F CE     1 
ATOM   1281 N NZ     . LYS C 3 22 ? 24.26995  12.45145  -0.44076  1.000 62.69883 ? 186 LYS F NZ     1 
ATOM   1282 H H      . LYS C 3 22 ? 19.67481  14.91905  2.38549   1.000 36.03122 ? 186 LYS F H      1 
ATOM   1283 H HA     . LYS C 3 22 ? 20.63233  12.58049  2.81635   1.000 38.51535 ? 186 LYS F HA     1 
ATOM   1284 H HB2    . LYS C 3 22 ? 21.85070  15.10590  3.19092   1.000 48.02138 ? 186 LYS F HB2    1 
ATOM   1285 H HB3    . LYS C 3 22 ? 22.66731  13.76659  3.44542   1.000 48.02138 ? 186 LYS F HB3    1 
ATOM   1286 H HG2    . LYS C 3 22 ? 22.07541  13.32110  1.07281   1.000 58.39472 ? 186 LYS F HG2    1 
ATOM   1287 H HG3    . LYS C 3 22 ? 21.96336  14.90529  1.01630   1.000 58.39472 ? 186 LYS F HG3    1 
ATOM   1288 H HD2    . LYS C 3 22 ? 24.08916  14.86927  0.57994   1.000 66.68969 ? 186 LYS F HD2    1 
ATOM   1289 H HD3    . LYS C 3 22 ? 24.28350  14.57686  2.12982   1.000 66.68969 ? 186 LYS F HD3    1 
ATOM   1290 H HE2    . LYS C 3 22 ? 25.48648  12.96773  1.08853   1.000 73.40544 ? 186 LYS F HE2    1 
ATOM   1291 H HE3    . LYS C 3 22 ? 24.16320  12.22806  1.56520   1.000 73.40544 ? 186 LYS F HE3    1 
ATOM   1292 H HZ1    . LYS C 3 22 ? 24.65463  11.66157  -0.58293  1.000 75.23860 ? 186 LYS F HZ1    1 
ATOM   1293 H HZ2    . LYS C 3 22 ? 23.39444  12.37588  -0.58172  1.000 75.23860 ? 186 LYS F HZ2    1 
ATOM   1294 H HZ3    . LYS C 3 22 ? 24.60491  13.04335  -1.01484  1.000 75.23860 ? 186 LYS F HZ3    1 
ATOM   1295 N N      . ASP C 3 23 ? 19.88090  14.07295  5.49989   1.000 29.59125 ? 187 ASP F N      1 
ATOM   1296 C CA     . ASP C 3 23 ? 19.78933  13.92797  6.94238   1.000 29.27715 ? 187 ASP F CA     1 
ATOM   1297 C C      . ASP C 3 23 ? 18.68384  12.97514  7.37539   1.000 25.06133 ? 187 ASP F C      1 
ATOM   1298 O O      . ASP C 3 23 ? 18.57134  12.68998  8.57279   1.000 24.68065 ? 187 ASP F O      1 
ATOM   1299 C CB     . ASP C 3 23 ? 19.58092  15.29542  7.58559   1.000 34.74121 ? 187 ASP F CB     1 
ATOM   1300 C CG     . ASP C 3 23 ? 20.76648  16.22151  7.36449   1.000 41.12716 ? 187 ASP F CG     1 
ATOM   1301 O OD1    . ASP C 3 23 ? 21.90718  15.71587  7.27177   1.000 42.24761 ? 187 ASP F OD1    1 
ATOM   1302 O OD2    . ASP C 3 23 ? 20.55977  17.44583  7.27351   1.000 45.32597 ? 187 ASP F OD2    1 
ATOM   1303 H H      . ASP C 3 23 ? 19.42389  14.72735  5.17972   1.000 35.50950 ? 187 ASP F H      1 
ATOM   1304 H HA     . ASP C 3 23 ? 20.62521  13.56895  7.27900   1.000 35.13258 ? 187 ASP F HA     1 
ATOM   1305 H HB2    . ASP C 3 23 ? 18.79529  15.71258  7.19874   1.000 41.68946 ? 187 ASP F HB2    1 
ATOM   1306 H HB3    . ASP C 3 23 ? 19.45988  15.18235  8.54135   1.000 41.68946 ? 187 ASP F HB3    1 
ATOM   1307 N N      . SER C 3 24 ? 17.86926  12.47102  6.44066   1.000 23.08245 ? 188 SER F N      1 
ATOM   1308 C CA     . SER C 3 24 ? 16.83461  11.49745  6.76129   1.000 20.96318 ? 188 SER F CA     1 
ATOM   1309 C C      . SER C 3 24 ? 17.15076  10.08675  6.28615   1.000 19.95923 ? 188 SER F C      1 
ATOM   1310 O O      . SER C 3 24 ? 16.58613  9.13229   6.82854   1.000 19.24744 ? 188 SER F O      1 
ATOM   1311 C CB     . SER C 3 24 ? 15.49233  11.90133  6.12826   1.000 20.28233 ? 188 SER F CB     1 
ATOM   1312 O OG     . SER C 3 24 ? 15.02520  13.15113  6.58848   1.000 22.39636 ? 188 SER F OG     1 
ATOM   1313 H H      . SER C 3 24 ? 17.90112  12.68289  5.60778   1.000 27.69893 ? 188 SER F H      1 
ATOM   1314 H HA     . SER C 3 24 ? 16.73019  11.48540  7.72558   1.000 25.15582 ? 188 SER F HA     1 
ATOM   1315 H HB2    . SER C 3 24 ? 15.60795  11.95092  5.16645   1.000 24.33880 ? 188 SER F HB2    1 
ATOM   1316 H HB3    . SER C 3 24 ? 14.83219  11.22565  6.34864   1.000 24.33880 ? 188 SER F HB3    1 
ATOM   1317 H HG     . SER C 3 24 ? 14.24761  13.29014  6.30278   1.000 26.87563 ? 188 SER F HG     1 
ATOM   1318 N N      . ILE C 3 25 ? 17.98738  9.94021   5.26186   1.000 19.82582 ? 189 ILE F N      1 
ATOM   1319 C CA     . ILE C 3 25 ? 18.24620  8.64821   4.63911   1.000 18.68267 ? 189 ILE F CA     1 
ATOM   1320 C C      . ILE C 3 25 ? 19.63390  8.70891   4.01609   1.000 19.21755 ? 189 ILE F C      1 
ATOM   1321 O O      . ILE C 3 25 ? 20.06538  9.76253   3.53015   1.000 21.87805 ? 189 ILE F O      1 
ATOM   1322 C CB     . ILE C 3 25 ? 17.15587  8.29009   3.59110   1.000 17.84787 ? 189 ILE F CB     1 
ATOM   1323 C CG1    . ILE C 3 25 ? 17.26943  6.82741   3.16627   1.000 18.91814 ? 189 ILE F CG1    1 
ATOM   1324 C CG2    . ILE C 3 25 ? 17.24386  9.20973   2.37117   1.000 20.91145 ? 189 ILE F CG2    1 
ATOM   1325 C CD1    . ILE C 3 25 ? 16.17998  6.37937   2.21550   1.000 19.31726 ? 189 ILE F CD1    1 
ATOM   1326 H H      . ILE C 3 25 ? 18.42518  10.58796  4.90359   1.000 23.79099 ? 189 ILE F H      1 
ATOM   1327 H HA     . ILE C 3 25 ? 18.24438  7.94905   5.31148   1.000 22.41921 ? 189 ILE F HA     1 
ATOM   1328 H HB     . ILE C 3 25 ? 16.29118  8.42117   4.01067   1.000 21.41744 ? 189 ILE F HB     1 
ATOM   1329 H HG12   . ILE C 3 25 ? 18.12165  6.69752   2.72158   1.000 22.70177 ? 189 ILE F HG12   1 
ATOM   1330 H HG13   . ILE C 3 25 ? 17.21950  6.26851   3.95749   1.000 22.70177 ? 189 ILE F HG13   1 
ATOM   1331 H HG21   . ILE C 3 25 ? 16.44276  9.10087   1.83518   1.000 25.09374 ? 189 ILE F HG21   1 
ATOM   1332 H HG22   . ILE C 3 25 ? 17.31754  10.12861  2.67305   1.000 25.09374 ? 189 ILE F HG22   1 
ATOM   1333 H HG23   . ILE C 3 25 ? 18.02576  8.96907   1.85001   1.000 25.09374 ? 189 ILE F HG23   1 
ATOM   1334 H HD11   . ILE C 3 25 ? 16.22211  5.41512   2.11880   1.000 23.18071 ? 189 ILE F HD11   1 
ATOM   1335 H HD12   . ILE C 3 25 ? 15.31831  6.63811   2.57811   1.000 23.18071 ? 189 ILE F HD12   1 
ATOM   1336 H HD13   . ILE C 3 25 ? 16.31768  6.80448   1.35456   1.000 23.18071 ? 189 ILE F HD13   1 
ATOM   1337 N N      . TRP C 3 26 ? 20.33631  7.57707   4.03899   1.000 18.95832 ? 190 TRP F N      1 
ATOM   1338 C CA     . TRP C 3 26 ? 21.68734  7.52691   3.48185   1.000 18.31901 ? 190 TRP F CA     1 
ATOM   1339 C C      . TRP C 3 26 ? 22.06845  6.09560   3.12274   1.000 19.32596 ? 190 TRP F C      1 
ATOM   1340 O O      . TRP C 3 26 ? 21.54595  5.12792   3.68200   1.000 19.06826 ? 190 TRP F O      1 
ATOM   1341 C CB     . TRP C 3 26 ? 22.72133  8.10698   4.46215   1.000 20.53927 ? 190 TRP F CB     1 
ATOM   1342 C CG     . TRP C 3 26 ? 22.60616  7.57609   5.86176   1.000 20.53829 ? 190 TRP F CG     1 
ATOM   1343 C CD1    . TRP C 3 26 ? 23.07253  6.37388   6.33662   1.000 22.11993 ? 190 TRP F CD1    1 
ATOM   1344 C CD2    . TRP C 3 26 ? 21.96481  8.21920   6.96412   1.000 21.14499 ? 190 TRP F CD2    1 
ATOM   1345 N NE1    . TRP C 3 26 ? 22.74898  6.23511   7.66934   1.000 22.51113 ? 190 TRP F NE1    1 
ATOM   1346 C CE2    . TRP C 3 26 ? 22.08427  7.35998   8.07907   1.000 21.86808 ? 190 TRP F CE2    1 
ATOM   1347 C CE3    . TRP C 3 26 ? 21.30509  9.44597   7.12333   1.000 22.46077 ? 190 TRP F CE3    1 
ATOM   1348 C CZ2    . TRP C 3 26 ? 21.55933  7.68461   9.32730   1.000 21.89355 ? 190 TRP F CZ2    1 
ATOM   1349 C CZ3    . TRP C 3 26 ? 20.79408  9.76616   8.37034   1.000 24.06038 ? 190 TRP F CZ3    1 
ATOM   1350 C CH2    . TRP C 3 26 ? 20.93826  8.89605   9.45538   1.000 22.91984 ? 190 TRP F CH2    1 
ATOM   1351 H H      . TRP C 3 26 ? 20.05633  6.83329   4.36763   1.000 22.74998 ? 190 TRP F H      1 
ATOM   1352 H HA     . TRP C 3 26 ? 21.68787  8.04502   2.66181   1.000 21.98281 ? 190 TRP F HA     1 
ATOM   1353 H HB2    . TRP C 3 26 ? 23.61026  7.89282   4.13837   1.000 24.64713 ? 190 TRP F HB2    1 
ATOM   1354 H HB3    . TRP C 3 26 ? 22.60562  9.06923   4.50193   1.000 24.64713 ? 190 TRP F HB3    1 
ATOM   1355 H HD1    . TRP C 3 26 ? 23.53814  5.74600   5.83276   1.000 26.54392 ? 190 TRP F HD1    1 
ATOM   1356 H HE1    . TRP C 3 26 ? 22.93394  5.55480   8.16186   1.000 27.01336 ? 190 TRP F HE1    1 
ATOM   1357 H HE3    . TRP C 3 26 ? 21.21257  10.03208  6.40721   1.000 26.95292 ? 190 TRP F HE3    1 
ATOM   1358 H HZ2    . TRP C 3 26 ? 21.62854  7.09945   10.04681  1.000 26.27226 ? 190 TRP F HZ2    1 
ATOM   1359 H HZ3    . TRP C 3 26 ? 20.34756  10.57344  8.48790   1.000 28.87246 ? 190 TRP F HZ3    1 
ATOM   1360 H HH2    . TRP C 3 26 ? 20.60311  9.14778   10.28557  1.000 27.50380 ? 190 TRP F HH2    1 
ATOM   1361 N N      . TRP C 3 27 ? 23.02186  5.97298   2.19845   1.000 19.67419 ? 191 TRP F N      1 
ATOM   1362 C CA     . TRP C 3 27 ? 23.58531  4.66790   1.89841   1.000 20.18181 ? 191 TRP F CA     1 
ATOM   1363 C C      . TRP C 3 27 ? 24.46331  4.19358   3.05163   1.000 19.75408 ? 191 TRP F C      1 
ATOM   1364 O O      . TRP C 3 27 ? 25.17885  4.98356   3.67235   1.000 21.43842 ? 191 TRP F O      1 
ATOM   1365 C CB     . TRP C 3 27 ? 24.47990  4.74954   0.66131   1.000 20.93619 ? 191 TRP F CB     1 
ATOM   1366 C CG     . TRP C 3 27 ? 23.79870  4.96704   -0.65591  1.000 21.67399 ? 191 TRP F CG     1 
ATOM   1367 C CD1    . TRP C 3 27 ? 23.96268  6.04134   -1.48460  1.000 21.66186 ? 191 TRP F CD1    1 
ATOM   1368 C CD2    . TRP C 3 27 ? 22.88383  4.08542   -1.31986  1.000 21.08097 ? 191 TRP F CD2    1 
ATOM   1369 N NE1    . TRP C 3 27 ? 23.19649  5.88415   -2.61744  1.000 21.84614 ? 191 TRP F NE1    1 
ATOM   1370 C CE2    . TRP C 3 27 ? 22.53232  4.69105   -2.54414  1.000 20.79125 ? 191 TRP F CE2    1 
ATOM   1371 C CE3    . TRP C 3 27 ? 22.33152  2.84349   -1.00103  1.000 20.77198 ? 191 TRP F CE3    1 
ATOM   1372 C CZ2    . TRP C 3 27 ? 21.64425  4.10327   -3.43809  1.000 21.72451 ? 191 TRP F CZ2    1 
ATOM   1373 C CZ3    . TRP C 3 27 ? 21.46046  2.26012   -1.89027  1.000 20.84484 ? 191 TRP F CZ3    1 
ATOM   1374 C CH2    . TRP C 3 27 ? 21.12296  2.89043   -3.09330  1.000 21.64860 ? 191 TRP F CH2    1 
ATOM   1375 H H      . TRP C 3 27 ? 23.35137  6.62231   1.74085   1.000 23.60903 ? 191 TRP F H      1 
ATOM   1376 H HA     . TRP C 3 27 ? 22.85750  4.04497   1.74623   1.000 24.21817 ? 191 TRP F HA     1 
ATOM   1377 H HB2    . TRP C 3 27 ? 25.09639  5.48804   0.78565   1.000 25.12342 ? 191 TRP F HB2    1 
ATOM   1378 H HB3    . TRP C 3 27 ? 24.97075  3.91586   0.59103   1.000 25.12342 ? 191 TRP F HB3    1 
ATOM   1379 H HD1    . TRP C 3 27 ? 24.51135  6.77142   -1.30899  1.000 25.99423 ? 191 TRP F HD1    1 
ATOM   1380 H HE1    . TRP C 3 27 ? 23.14399  6.44577   -3.26661  1.000 26.21537 ? 191 TRP F HE1    1 
ATOM   1381 H HE3    . TRP C 3 27 ? 22.54868  2.41906   -0.20253  1.000 24.92638 ? 191 TRP F HE3    1 
ATOM   1382 H HZ2    . TRP C 3 27 ? 21.41515  4.51942   -4.23761  1.000 26.06941 ? 191 TRP F HZ2    1 
ATOM   1383 H HZ3    . TRP C 3 27 ? 21.08880  1.43177   -1.68877  1.000 25.01381 ? 191 TRP F HZ3    1 
ATOM   1384 H HH2    . TRP C 3 27 ? 20.52802  2.47181   -3.67269  1.000 25.97832 ? 191 TRP F HH2    1 
ATOM   1385 N N      . VAL C 3 28 ? 24.41423  2.88906   3.32856   1.000 20.15985 ? 192 VAL F N      1 
ATOM   1386 C CA     . VAL C 3 28 ? 25.36577  2.24040   4.22701   1.000 20.01331 ? 192 VAL F CA     1 
ATOM   1387 C C      . VAL C 3 28 ? 26.49129  1.65132   3.38625   1.000 19.29568 ? 192 VAL F C      1 
ATOM   1388 O O      . VAL C 3 28 ? 27.66567  1.97273   3.58069   1.000 21.76282 ? 192 VAL F O      1 
ATOM   1389 C CB     . VAL C 3 28 ? 24.66864  1.16056   5.07486   1.000 20.40651 ? 192 VAL F CB     1 
ATOM   1390 C CG1    . VAL C 3 28 ? 25.69808  0.41161   5.91152   1.000 22.32302 ? 192 VAL F CG1    1 
ATOM   1391 C CG2    . VAL C 3 28 ? 23.60016  1.80488   5.94893   1.000 20.70360 ? 192 VAL F CG2    1 
ATOM   1392 H H      . VAL C 3 28 ? 23.82853  2.35057   3.00210   1.000 24.19182 ? 192 VAL F H      1 
ATOM   1393 H HA     . VAL C 3 28 ? 25.74685  2.89324   4.83485   1.000 24.01597 ? 192 VAL F HA     1 
ATOM   1394 H HB     . VAL C 3 28 ? 24.23229  0.51409   4.49818   1.000 24.48781 ? 192 VAL F HB     1 
ATOM   1395 H HG11   . VAL C 3 28 ? 25.23918  -0.08282  6.60856   1.000 26.78762 ? 192 VAL F HG11   1 
ATOM   1396 H HG12   . VAL C 3 28 ? 26.18603  -0.20025  5.33844   1.000 26.78762 ? 192 VAL F HG12   1 
ATOM   1397 H HG13   . VAL C 3 28 ? 26.30924  1.05213   6.30791   1.000 26.78762 ? 192 VAL F HG13   1 
ATOM   1398 H HG21   . VAL C 3 28 ? 23.20426  1.12513   6.51647   1.000 24.84432 ? 192 VAL F HG21   1 
ATOM   1399 H HG22   . VAL C 3 28 ? 24.01151  2.49312   6.49485   1.000 24.84432 ? 192 VAL F HG22   1 
ATOM   1400 H HG23   . VAL C 3 28 ? 22.92023  2.19710   5.37905   1.000 24.84432 ? 192 VAL F HG23   1 
ATOM   1401 N N      . ASP C 3 29 ? 26.13013  0.78376   2.43778   1.000 20.51005 ? 193 ASP F N      1 
ATOM   1402 C CA     . ASP C 3 29 ? 27.06687  0.27176   1.43686   1.000 20.94284 ? 193 ASP F CA     1 
ATOM   1403 C C      . ASP C 3 29 ? 26.33293  0.30886   0.09669   1.000 21.52980 ? 193 ASP F C      1 
ATOM   1404 O O      . ASP C 3 29 ? 25.52001  -0.57080  -0.21132  1.000 19.76953 ? 193 ASP F O      1 
ATOM   1405 C CB     . ASP C 3 29 ? 27.56120  -1.12839  1.78549   1.000 22.51282 ? 193 ASP F CB     1 
ATOM   1406 C CG     . ASP C 3 29 ? 28.62940  -1.62319  0.82500   1.000 24.44796 ? 193 ASP F CG     1 
ATOM   1407 O OD1    . ASP C 3 29 ? 28.66918  -1.11519  -0.31809  1.000 24.52201 ? 193 ASP F OD1    1 
ATOM   1408 O OD2    . ASP C 3 29 ? 29.44354  -2.50881  1.20298   1.000 25.77088 ? 193 ASP F OD2    1 
ATOM   1409 H H      . ASP C 3 29 ? 25.33326  0.47178   2.35260   1.000 24.61206 ? 193 ASP F H      1 
ATOM   1410 H HA     . ASP C 3 29 ? 27.84693  0.84605   1.38584   1.000 25.13140 ? 193 ASP F HA     1 
ATOM   1411 H HB2    . ASP C 3 29 ? 27.94053  -1.11769  2.67818   1.000 27.01539 ? 193 ASP F HB2    1 
ATOM   1412 H HB3    . ASP C 3 29 ? 26.81445  -1.74644  1.74973   1.000 27.01539 ? 193 ASP F HB3    1 
ATOM   1413 N N      . LYS C 3 30 ? 26.59069  1.35097   -0.68727  1.000 24.85363 ? 194 LYS F N      1 
ATOM   1414 C CA     . LYS C 3 30 ? 25.79656  1.51774   -1.90135  1.000 27.34052 ? 194 LYS F CA     1 
ATOM   1415 C C      . LYS C 3 30 ? 26.03657  0.38449   -2.88923  1.000 25.87728 ? 194 LYS F C      1 
ATOM   1416 O O      . LYS C 3 30 ? 25.12100  0.01733   -3.63397  1.000 25.90315 ? 194 LYS F O      1 
ATOM   1417 C CB     . LYS C 3 30 ? 26.03993  2.88905   -2.52506  1.000 32.29669 ? 194 LYS F CB     1 
ATOM   1418 C CG     . LYS C 3 30 ? 27.48894  3.16395   -2.84235  1.000 33.91259 ? 194 LYS F CG     1 
ATOM   1419 C CD     . LYS C 3 30 ? 27.72458  4.64148   -3.15618  1.000 38.90387 ? 194 LYS F CD     1 
ATOM   1420 C CE     . LYS C 3 30 ? 29.21256  4.97631   -3.19922  1.000 42.76506 ? 194 LYS F CE     1 
ATOM   1421 N NZ     . LYS C 3 30 ? 29.44504  6.44909   -3.28307  1.000 45.57485 ? 194 LYS F NZ     1 
ATOM   1422 H H      . LYS C 3 30 ? 27.19207  1.94946   -0.54676  1.000 29.82436 ? 194 LYS F H      1 
ATOM   1423 H HA     . LYS C 3 30 ? 24.85545  1.49302   -1.66767  1.000 32.80863 ? 194 LYS F HA     1 
ATOM   1424 H HB2    . LYS C 3 30 ? 25.53900  2.94806   -3.35360  1.000 38.75603 ? 194 LYS F HB2    1 
ATOM   1425 H HB3    . LYS C 3 30 ? 25.73784  3.57146   -1.90541  1.000 38.75603 ? 194 LYS F HB3    1 
ATOM   1426 H HG2    . LYS C 3 30 ? 28.03613  2.92378   -2.07828  1.000 40.69511 ? 194 LYS F HG2    1 
ATOM   1427 H HG3    . LYS C 3 30 ? 27.75272  2.64228   -3.61642  1.000 40.69511 ? 194 LYS F HG3    1 
ATOM   1428 H HD2    . LYS C 3 30 ? 27.34026  4.85095   -4.02181  1.000 46.68465 ? 194 LYS F HD2    1 
ATOM   1429 H HD3    . LYS C 3 30 ? 27.30987  5.18569   -2.46861  1.000 46.68465 ? 194 LYS F HD3    1 
ATOM   1430 H HE2    . LYS C 3 30 ? 29.63857  4.64656   -2.39258  1.000 51.31807 ? 194 LYS F HE2    1 
ATOM   1431 H HE3    . LYS C 3 30 ? 29.61206  4.56042   -3.97918  1.000 51.31807 ? 194 LYS F HE3    1 
ATOM   1432 H HZ1    . LYS C 3 30 ? 30.31821  6.62074   -3.26856  1.000 54.68982 ? 194 LYS F HZ1    1 
ATOM   1433 H HZ2    . LYS C 3 30 ? 29.10028  6.76916   -4.03858  1.000 54.68982 ? 194 LYS F HZ2    1 
ATOM   1434 H HZ3    . LYS C 3 30 ? 29.05880  6.85799   -2.59334  1.000 54.68982 ? 194 LYS F HZ3    1 
ATOM   1435 N N      . ASP C 3 31 ? 27.24245  -0.19574  -2.89477  1.000 24.60492 ? 195 ASP F N      1 
ATOM   1436 C CA     . ASP C 3 31 ? 27.51276  -1.32538  -3.77893  1.000 24.17782 ? 195 ASP F CA     1 
ATOM   1437 C C      . ASP C 3 31 ? 26.59838  -2.50199  -3.47686  1.000 24.92668 ? 195 ASP F C      1 
ATOM   1438 O O      . ASP C 3 31 ? 26.23147  -3.25259  -4.38856  1.000 26.76264 ? 195 ASP F O      1 
ATOM   1439 C CB     . ASP C 3 31 ? 28.95946  -1.78167  -3.61519  1.000 24.49658 ? 195 ASP F CB     1 
ATOM   1440 C CG     . ASP C 3 31 ? 29.95681  -0.79481  -4.16995  1.000 25.33313 ? 195 ASP F CG     1 
ATOM   1441 O OD1    . ASP C 3 31 ? 29.76204  0.43934   -4.04433  1.000 26.04729 ? 195 ASP F OD1    1 
ATOM   1442 O OD2    . ASP C 3 31 ? 30.95211  -1.27546  -4.72275  1.000 26.97346 ? 195 ASP F OD2    1 
ATOM   1443 H H      . ASP C 3 31 ? 27.90706  0.04338   -2.40414  1.000 29.52591 ? 195 ASP F H      1 
ATOM   1444 H HA     . ASP C 3 31 ? 27.36909  -1.03562  -4.69342  1.000 29.01338 ? 195 ASP F HA     1 
ATOM   1445 H HB2    . ASP C 3 31 ? 29.14804  -1.89797  -2.67083  1.000 29.39589 ? 195 ASP F HB2    1 
ATOM   1446 H HB3    . ASP C 3 31 ? 29.07935  -2.62265  -4.08346  1.000 29.39589 ? 195 ASP F HB3    1 
ATOM   1447 N N      . LYS C 3 32 ? 26.26007  -2.70401  -2.20293  1.000 22.21916 ? 196 LYS F N      1 
ATOM   1448 C CA     . LYS C 3 32 ? 25.34261  -3.75986  -1.79136  1.000 22.34765 ? 196 LYS F CA     1 
ATOM   1449 C C      . LYS C 3 32 ? 23.88828  -3.32308  -1.82953  1.000 21.08539 ? 196 LYS F C      1 
ATOM   1450 O O      . LYS C 3 32 ? 22.99402  -4.15732  -1.62886  1.000 22.64633 ? 196 LYS F O      1 
ATOM   1451 C CB     . LYS C 3 32 ? 25.68822  -4.20847  -0.36116  1.000 24.02970 ? 196 LYS F CB     1 
ATOM   1452 C CG     . LYS C 3 32 ? 27.04152  -4.90176  -0.22909  1.000 25.98772 ? 196 LYS F CG     1 
ATOM   1453 C CD     . LYS C 3 32 ? 27.33009  -5.31017  1.20560   1.000 27.94721 ? 196 LYS F CD     1 
ATOM   1454 C CE     . LYS C 3 32 ? 28.69385  -5.98723  1.32340   1.000 31.96077 ? 196 LYS F CE     1 
ATOM   1455 N NZ     . LYS C 3 32 ? 29.05656  -6.31695  2.73854   1.000 33.81022 ? 196 LYS F NZ     1 
ATOM   1456 H H      . LYS C 3 32 ? 26.55573  -2.23221  -1.54750  1.000 26.66299 ? 196 LYS F H      1 
ATOM   1457 H HA     . LYS C 3 32 ? 25.44445  -4.51798  -2.38784  1.000 26.81718 ? 196 LYS F HA     1 
ATOM   1458 H HB2    . LYS C 3 32 ? 25.70114  -3.42726  0.21368   1.000 28.83564 ? 196 LYS F HB2    1 
ATOM   1459 H HB3    . LYS C 3 32 ? 25.00854  -4.83124  -0.05934  1.000 28.83564 ? 196 LYS F HB3    1 
ATOM   1460 H HG2    . LYS C 3 32 ? 27.04664  -5.70089  -0.77887  1.000 31.18526 ? 196 LYS F HG2    1 
ATOM   1461 H HG3    . LYS C 3 32 ? 27.74121  -4.29548  -0.51850  1.000 31.18526 ? 196 LYS F HG3    1 
ATOM   1462 H HD2    . LYS C 3 32 ? 27.32958  -4.52232  1.77145   1.000 33.53666 ? 196 LYS F HD2    1 
ATOM   1463 H HD3    . LYS C 3 32 ? 26.65132  -5.93470  1.50582   1.000 33.53666 ? 196 LYS F HD3    1 
ATOM   1464 H HE2    . LYS C 3 32 ? 28.68122  -6.81429  0.81673   1.000 38.35292 ? 196 LYS F HE2    1 
ATOM   1465 H HE3    . LYS C 3 32 ? 29.37389  -5.39233  0.97050   1.000 38.35292 ? 196 LYS F HE3    1 
ATOM   1466 H HZ1    . LYS C 3 32 ? 28.53901  -6.97528  3.03995   1.000 40.57226 ? 196 LYS F HZ1    1 
ATOM   1467 H HZ2    . LYS C 3 32 ? 29.90718  -6.57507  2.78252   1.000 40.57226 ? 196 LYS F HZ2    1 
ATOM   1468 H HZ3    . LYS C 3 32 ? 28.94467  -5.60157  3.25604   1.000 40.57226 ? 196 LYS F HZ3    1 
ATOM   1469 N N      . GLY C 3 33 ? 23.64201  -2.03691  -2.04169  1.000 21.84675 ? 197 GLY F N      1 
ATOM   1470 C CA     . GLY C 3 33 ? 22.30677  -1.49951  -1.98224  1.000 21.13209 ? 197 GLY F CA     1 
ATOM   1471 C C      . GLY C 3 33 ? 21.71426  -1.34940  -0.60394  1.000 19.81450 ? 197 GLY F C      1 
ATOM   1472 O O      . GLY C 3 33 ? 20.48807  -1.22900  -0.48837  1.000 20.13832 ? 197 GLY F O      1 
ATOM   1473 H H      . GLY C 3 33 ? 24.24461  -1.45111  -2.22422  1.000 26.21610 ? 197 GLY F H      1 
ATOM   1474 H HA2    . GLY C 3 33 ? 22.31194  -0.62106  -2.39356  1.000 25.35851 ? 197 GLY F HA2    1 
ATOM   1475 H HA3    . GLY C 3 33 ? 21.71968  -2.08207  -2.48904  1.000 25.35851 ? 197 GLY F HA3    1 
ATOM   1476 N N      . THR C 3 34 ? 22.53903  -1.32286  0.44586   1.000 19.56860 ? 198 THR F N      1 
ATOM   1477 C CA     . THR C 3 34 ? 22.02491  -1.16302  1.79606   1.000 18.61779 ? 198 THR F CA     1 
ATOM   1478 C C      . THR C 3 34 ? 21.92432  0.31386   2.15196   1.000 18.36750 ? 198 THR F C      1 
ATOM   1479 O O      . THR C 3 34 ? 22.80573  1.11345   1.81375   1.000 18.99868 ? 198 THR F O      1 
ATOM   1480 C CB     . THR C 3 34 ? 22.89641  -1.89279  2.81253   1.000 18.25343 ? 198 THR F CB     1 
ATOM   1481 O OG1    . THR C 3 34 ? 24.24798  -1.46553  2.66097   1.000 20.42395 ? 198 THR F OG1    1 
ATOM   1482 C CG2    . THR C 3 34 ? 22.81386  -3.40981  2.62652   1.000 19.68801 ? 198 THR F CG2    1 
ATOM   1483 H H      . THR C 3 34 ? 23.39452  -1.39552  0.39619   1.000 23.48232 ? 198 THR F H      1 
ATOM   1484 H HA     . THR C 3 34 ? 21.13641  -1.54943  1.84243   1.000 22.34135 ? 198 THR F HA     1 
ATOM   1485 H HB     . THR C 3 34 ? 22.58493  -1.69016  3.70853   1.000 21.90412 ? 198 THR F HB     1 
ATOM   1486 H HG1    . THR C 3 34 ? 24.73601  -1.85031  3.22608   1.000 24.50874 ? 198 THR F HG1    1 
ATOM   1487 H HG21   . THR C 3 34 ? 23.36648  -3.85565  3.28738   1.000 23.62561 ? 198 THR F HG21   1 
ATOM   1488 H HG22   . THR C 3 34 ? 21.89654  -3.70741  2.73077   1.000 23.62561 ? 198 THR F HG22   1 
ATOM   1489 H HG23   . THR C 3 34 ? 23.12487  -3.65282  1.74045   1.000 23.62561 ? 198 THR F HG23   1 
ATOM   1490 N N      . PHE C 3 35 ? 20.82501  0.67244   2.81561   1.000 17.38591 ? 199 PHE F N      1 
ATOM   1491 C CA     . PHE C 3 35 ? 20.57456  2.05408   3.19474   1.000 17.24153 ? 199 PHE F CA     1 
ATOM   1492 C C      . PHE C 3 35 ? 19.88557  2.08633   4.54983   1.000 16.83852 ? 199 PHE F C      1 
ATOM   1493 O O      . PHE C 3 35 ? 19.33063  1.08575   5.00129   1.000 18.12750 ? 199 PHE F O      1 
ATOM   1494 C CB     . PHE C 3 35 ? 19.74218  2.78560   2.13822   1.000 18.38682 ? 199 PHE F CB     1 
ATOM   1495 C CG     . PHE C 3 35 ? 18.35911  2.21748   1.92353   1.000 17.91775 ? 199 PHE F CG     1 
ATOM   1496 C CD1    . PHE C 3 35 ? 18.15625  1.14797   1.05442   1.000 17.32879 ? 199 PHE F CD1    1 
ATOM   1497 C CD2    . PHE C 3 35 ? 17.25937  2.76956   2.56632   1.000 18.59613 ? 199 PHE F CD2    1 
ATOM   1498 C CE1    . PHE C 3 35 ? 16.87200  0.64771   0.83628   1.000 17.56078 ? 199 PHE F CE1    1 
ATOM   1499 C CE2    . PHE C 3 35 ? 15.98283  2.27310   2.33858   1.000 18.48725 ? 199 PHE F CE2    1 
ATOM   1500 C CZ     . PHE C 3 35 ? 15.79931  1.21704   1.47266   1.000 17.60489 ? 199 PHE F CZ     1 
ATOM   1501 H H      . PHE C 3 35 ? 20.20667  0.12595   3.05772   1.000 20.86309 ? 199 PHE F H      1 
ATOM   1502 H HA     . PHE C 3 35 ? 21.41780  2.52500   3.28467   1.000 20.68983 ? 199 PHE F HA     1 
ATOM   1503 H HB2    . PHE C 3 35 ? 19.63921  3.71034   2.41235   1.000 22.06418 ? 199 PHE F HB2    1 
ATOM   1504 H HB3    . PHE C 3 35 ? 20.21146  2.74117   1.29046   1.000 22.06418 ? 199 PHE F HB3    1 
ATOM   1505 H HD1    . PHE C 3 35 ? 18.88170  0.76471   0.61656   1.000 20.79455 ? 199 PHE F HD1    1 
ATOM   1506 H HD2    . PHE C 3 35 ? 17.37891  3.47915   3.15546   1.000 22.31535 ? 199 PHE F HD2    1 
ATOM   1507 H HE1    . PHE C 3 35 ? 16.74388  -0.07090  0.26001   1.000 21.07294 ? 199 PHE F HE1    1 
ATOM   1508 H HE2    . PHE C 3 35 ? 15.25200  2.65316   2.77027   1.000 22.18470 ? 199 PHE F HE2    1 
ATOM   1509 H HZ     . PHE C 3 35 ? 14.94291  0.88858   1.31902   1.000 21.12587 ? 199 PHE F HZ     1 
ATOM   1510 N N      . GLN C 3 36 ? 19.91342  3.26254   5.18974   1.000 16.80951 ? 200 GLN F N      1 
ATOM   1511 C CA     . GLN C 3 36 ? 19.43419  3.41430   6.55100   1.000 17.55200 ? 200 GLN F CA     1 
ATOM   1512 C C      . GLN C 3 36 ? 18.69343  4.73789   6.71299   1.000 16.91506 ? 200 GLN F C      1 
ATOM   1513 O O      . GLN C 3 36 ? 19.08832  5.76043   6.13579   1.000 17.78178 ? 200 GLN F O      1 
ATOM   1514 C CB     . GLN C 3 36 ? 20.62883  3.35343   7.50823   1.000 19.41088 ? 200 GLN F CB     1 
ATOM   1515 C CG     . GLN C 3 36 ? 20.28055  3.51693   8.96772   1.000 20.57382 ? 200 GLN F CG     1 
ATOM   1516 C CD     . GLN C 3 36 ? 21.48489  3.41351   9.85561   1.000 23.49771 ? 200 GLN F CD     1 
ATOM   1517 O OE1    . GLN C 3 36 ? 22.53573  4.01751   9.58447   1.000 25.02282 ? 200 GLN F OE1    1 
ATOM   1518 N NE2    . GLN C 3 36 ? 21.35403  2.63152   10.92288  1.000 24.58909 ? 200 GLN F NE2    1 
ATOM   1519 H H      . GLN C 3 36 ? 20.21101  3.99155   4.84393   1.000 20.17141 ? 200 GLN F H      1 
ATOM   1520 H HA     . GLN C 3 36 ? 18.79662  2.71608   6.76753   1.000 21.06240 ? 200 GLN F HA     1 
ATOM   1521 H HB2    . GLN C 3 36 ? 21.06096  2.49099   7.40645   1.000 23.29306 ? 200 GLN F HB2    1 
ATOM   1522 H HB3    . GLN C 3 36 ? 21.24673  4.06373   7.27460   1.000 23.29306 ? 200 GLN F HB3    1 
ATOM   1523 H HG2    . GLN C 3 36 ? 19.87993  4.38991   9.10298   1.000 24.68858 ? 200 GLN F HG2    1 
ATOM   1524 H HG3    . GLN C 3 36 ? 19.65524  2.82146   9.22506   1.000 24.68858 ? 200 GLN F HG3    1 
ATOM   1525 H HE21   . GLN C 3 36 ? 20.61131  2.22303   11.06819  1.000 29.50691 ? 200 GLN F HE21   1 
ATOM   1526 H HE22   . GLN C 3 36 ? 22.01210  2.53419   11.46793  1.000 29.50691 ? 200 GLN F HE22   1 
ATOM   1527 N N      . PHE C 3 37 ? 17.61666  4.70689   7.50313   1.000 16.86014 ? 201 PHE F N      1 
ATOM   1528 C CA     . PHE C 3 37 ? 16.89751  5.91005   7.87524   1.000 17.09048 ? 201 PHE F CA     1 
ATOM   1529 C C      . PHE C 3 37 ? 17.43677  6.51344   9.16746   1.000 19.53840 ? 201 PHE F C      1 
ATOM   1530 O O      . PHE C 3 37 ? 17.95174  5.81089   10.03640  1.000 19.54782 ? 201 PHE F O      1 
ATOM   1531 C CB     . PHE C 3 37 ? 15.41066  5.59209   8.05162   1.000 17.06841 ? 201 PHE F CB     1 
ATOM   1532 C CG     . PHE C 3 37 ? 14.71644  5.17666   6.78526   1.000 17.30811 ? 201 PHE F CG     1 
ATOM   1533 C CD1    . PHE C 3 37 ? 14.28510  6.13138   5.88593   1.000 18.01028 ? 201 PHE F CD1    1 
ATOM   1534 C CD2    . PHE C 3 37 ? 14.50024  3.83802   6.49932   1.000 16.77166 ? 201 PHE F CD2    1 
ATOM   1535 C CE1    . PHE C 3 37 ? 13.61005  5.77061   4.73423   1.000 18.09046 ? 201 PHE F CE1    1 
ATOM   1536 C CE2    . PHE C 3 37 ? 13.82978  3.46939   5.35330   1.000 17.53913 ? 201 PHE F CE2    1 
ATOM   1537 C CZ     . PHE C 3 37 ? 13.39926  4.43113   4.46393   1.000 17.19673 ? 201 PHE F CZ     1 
ATOM   1538 H H      . PHE C 3 37 ? 17.28453  3.98734   7.83711   1.000 20.23217 ? 201 PHE F H      1 
ATOM   1539 H HA     . PHE C 3 37 ? 17.00929  6.57112   7.17425   1.000 20.50858 ? 201 PHE F HA     1 
ATOM   1540 H HB2    . PHE C 3 37 ? 15.32203  4.86537   8.68794   1.000 20.48209 ? 201 PHE F HB2    1 
ATOM   1541 H HB3    . PHE C 3 37 ? 14.96170  6.38367   8.38739   1.000 20.48209 ? 201 PHE F HB3    1 
ATOM   1542 H HD1    . PHE C 3 37 ? 14.45098  7.03029   6.05723   1.000 21.61233 ? 201 PHE F HD1    1 
ATOM   1543 H HD2    . PHE C 3 37 ? 14.80950  3.18458   7.08437   1.000 20.12599 ? 201 PHE F HD2    1 
ATOM   1544 H HE1    . PHE C 3 37 ? 13.30093  6.42246   4.14734   1.000 21.70855 ? 201 PHE F HE1    1 
ATOM   1545 H HE2    . PHE C 3 37 ? 13.66736  2.57035   5.17938   1.000 21.04695 ? 201 PHE F HE2    1 
ATOM   1546 H HZ     . PHE C 3 37 ? 12.96623  4.17832   3.68068   1.000 20.63608 ? 201 PHE F HZ     1 
ATOM   1547 N N      . SER C 3 38 ? 17.26432  7.82785   9.29181   1.000 19.48325 ? 202 SER F N      1 
ATOM   1548 C CA     . SER C 3 38 ? 17.56982  8.55017   10.51952  1.000 21.00032 ? 202 SER F CA     1 
ATOM   1549 C C      . SER C 3 38 ? 16.49153  8.29666   11.56348  1.000 20.86785 ? 202 SER F C      1 
ATOM   1550 O O      . SER C 3 38 ? 15.29827  8.47910   11.29670  1.000 20.89514 ? 202 SER F O      1 
ATOM   1551 C CB     . SER C 3 38 ? 17.59451  10.04243  10.21402  1.000 21.72353 ? 202 SER F CB     1 
ATOM   1552 O OG     . SER C 3 38 ? 17.62502  10.79184  11.41699  1.000 23.10735 ? 202 SER F OG     1 
ATOM   1553 H H      . SER C 3 38 ? 16.96474  8.33391   8.66430   1.000 23.37990 ? 202 SER F H      1 
ATOM   1554 H HA     . SER C 3 38 ? 18.42516  8.25435   10.86850  1.000 25.20038 ? 202 SER F HA     1 
ATOM   1555 H HB2    . SER C 3 38 ? 18.38628  10.24682  9.69227   1.000 26.06823 ? 202 SER F HB2    1 
ATOM   1556 H HB3    . SER C 3 38 ? 16.79756  10.27744  9.71348   1.000 26.06823 ? 202 SER F HB3    1 
ATOM   1557 H HG     . SER C 3 38 ? 17.65596  11.61307  11.24317  1.000 27.72882 ? 202 SER F HG     1 
ATOM   1558 N N      . SER C 3 39 ? 16.90547  7.92391   12.77306  1.000 23.40913 ? 203 SER F N      1 
ATOM   1559 C CA     . SER C 3 39 ? 15.93389  7.73631   13.84488  1.000 24.53689 ? 203 SER F CA     1 
ATOM   1560 C C      . SER C 3 39 ? 15.13729  9.01371   14.07854  1.000 25.14747 ? 203 SER F C      1 
ATOM   1561 O O      . SER C 3 39 ? 13.90028  8.98392   14.18375  1.000 25.16052 ? 203 SER F O      1 
ATOM   1562 C CB     . SER C 3 39 ? 16.64193  7.30891   15.12988  1.000 27.47198 ? 203 SER F CB     1 
ATOM   1563 O OG     . SER C 3 39 ? 15.70843  7.18012   16.18263  1.000 33.60656 ? 203 SER F OG     1 
ATOM   1564 H H      . SER C 3 39 ? 17.72361  7.77679   12.99353  1.000 28.09096 ? 203 SER F H      1 
ATOM   1565 H HA     . SER C 3 39 ? 15.31966  7.02985   13.59084  1.000 29.44427 ? 203 SER F HA     1 
ATOM   1566 H HB2    . SER C 3 39 ? 17.07714  6.45435   14.98423  1.000 32.96638 ? 203 SER F HB2    1 
ATOM   1567 H HB3    . SER C 3 39 ? 17.30027  7.98005   15.36873  1.000 32.96638 ? 203 SER F HB3    1 
ATOM   1568 H HG     . SER C 3 39 ? 16.09762  6.92566   16.88219  1.000 40.32787 ? 203 SER F HG     1 
ATOM   1569 N N      . LYS C 3 40 ? 15.82655  10.15418  14.12559  1.000 25.81969 ? 204 LYS F N      1 
ATOM   1570 C CA     . LYS C 3 40 ? 15.19827  11.41464  14.48887  1.000 26.03078 ? 204 LYS F CA     1 
ATOM   1571 C C      . LYS C 3 40 ? 14.56175  12.15079  13.31953  1.000 25.11448 ? 204 LYS F C      1 
ATOM   1572 O O      . LYS C 3 40 ? 13.68337  12.98710  13.54937  1.000 27.40651 ? 204 LYS F O      1 
ATOM   1573 C CB     . LYS C 3 40 ? 16.23197  12.34034  15.13493  0.898 30.80794 ? 204 LYS F CB     1 
ATOM   1574 C CG     . LYS C 3 40 ? 16.45914  12.06543  16.60133  0.678 34.55978 ? 204 LYS F CG     1 
ATOM   1575 C CD     . LYS C 3 40 ? 15.44949  12.79008  17.47113  0.761 38.21264 ? 204 LYS F CD     1 
ATOM   1576 C CE     . LYS C 3 40 ? 15.63596  14.30340  17.42830  0.361 40.91995 ? 204 LYS F CE     1 
ATOM   1577 N NZ     . LYS C 3 40 ? 14.68615  14.99095  18.32598  0.638 42.41452 ? 204 LYS F NZ     1 
ATOM   1578 H H      . LYS C 3 40 ? 16.66569  10.22049  13.94938  1.000 30.98362 ? 204 LYS F H      1 
ATOM   1579 H HA     . LYS C 3 40 ? 14.49617  11.22327  15.13022  1.000 31.23694 ? 204 LYS F HA     1 
ATOM   1580 H HB2    . LYS C 3 40 ? 17.08002  12.22864  14.67750  1.000 36.96953 ? 204 LYS F HB2    1 
ATOM   1581 H HB3    . LYS C 3 40 ? 15.92687  13.25709  15.04894  1.000 36.96953 ? 204 LYS F HB3    1 
ATOM   1582 H HG2    . LYS C 3 40 ? 16.37414  11.11327  16.76583  1.000 41.47173 ? 204 LYS F HG2    1 
ATOM   1583 H HG3    . LYS C 3 40 ? 17.34679  12.36717  16.85022  1.000 41.47173 ? 204 LYS F HG3    1 
ATOM   1584 H HD2    . LYS C 3 40 ? 14.55434  12.58686  17.15761  0.615 45.85517 ? 204 LYS F HD2    1 
ATOM   1585 H HD3    . LYS C 3 40 ? 15.55315  12.49867  18.39049  1.000 45.85517 ? 204 LYS F HD3    1 
ATOM   1586 H HE2    . LYS C 3 40 ? 16.53723  14.52409  17.71098  1.000 49.10394 ? 204 LYS F HE2    1 
ATOM   1587 H HE3    . LYS C 3 40 ? 15.48496  14.62016  16.52400  0.898 49.10394 ? 204 LYS F HE3    1 
ATOM   1588 H HZ1    . LYS C 3 40 ? 14.86903  15.86153  18.35343  1.000 50.89742 ? 204 LYS F HZ1    1 
ATOM   1589 H HZ2    . LYS C 3 40 ? 13.85379  14.87982  18.03114  0.385 50.89742 ? 204 LYS F HZ2    1 
ATOM   1590 H HZ3    . LYS C 3 40 ? 14.74827  14.65668  19.14848  0.475 50.89742 ? 204 LYS F HZ3    1 
ATOM   1591 N N      . HIS C 3 41 ? 14.96630  11.87192  12.07511  1.000 23.22373 ? 205 HIS F N      1 
ATOM   1592 C CA     . HIS C 3 41 ? 14.50656  12.66769  10.93772  1.000 22.41967 ? 205 HIS F CA     1 
ATOM   1593 C C      . HIS C 3 41 ? 13.78382  11.85586  9.87543   1.000 20.98089 ? 205 HIS F C      1 
ATOM   1594 O O      . HIS C 3 41 ? 13.49603  12.38468  8.78827   1.000 21.94043 ? 205 HIS F O      1 
ATOM   1595 C CB     . HIS C 3 41 ? 15.67742  13.46499  10.35848  1.000 23.10251 ? 205 HIS F CB     1 
ATOM   1596 C CG     . HIS C 3 41 ? 16.34555  14.31371  11.38050  1.000 25.22650 ? 205 HIS F CG     1 
ATOM   1597 N ND1    . HIS C 3 41 ? 15.70513  15.35857  12.01010  1.000 26.34804 ? 205 HIS F ND1    1 
ATOM   1598 C CD2    . HIS C 3 41 ? 17.58228  14.24821  11.91871  1.000 27.57592 ? 205 HIS F CD2    1 
ATOM   1599 C CE1    . HIS C 3 41 ? 16.52152  15.89676  12.90016  1.000 27.19702 ? 205 HIS F CE1    1 
ATOM   1600 N NE2    . HIS C 3 41 ? 17.66980  15.24756  12.85627  1.000 28.84403 ? 205 HIS F NE2    1 
ATOM   1601 H H      . HIS C 3 41 ? 15.50228  11.23174  11.86898  1.000 27.86848 ? 205 HIS F H      1 
ATOM   1602 H HA     . HIS C 3 41 ? 13.84995  13.30994  11.24960  1.000 26.90361 ? 205 HIS F HA     1 
ATOM   1603 H HB2    . HIS C 3 41 ? 16.33538  12.84812  10.00145  1.000 27.72301 ? 205 HIS F HB2    1 
ATOM   1604 H HB3    . HIS C 3 41 ? 15.34866  14.04418  9.65325   1.000 27.72301 ? 205 HIS F HB3    1 
ATOM   1605 H HD2    . HIS C 3 41 ? 18.24977  13.64011  11.69606  1.000 33.09110 ? 205 HIS F HD2    1 
ATOM   1606 H HE1    . HIS C 3 41 ? 16.32088  16.61077  13.46125  1.000 32.63642 ? 205 HIS F HE1    1 
ATOM   1607 H HE2    . HIS C 3 41 ? 18.36107  15.42222  13.33714  1.000 34.61284 ? 205 HIS F HE2    1 
ATOM   1608 N N      . LYS C 3 42 ? 13.42976  10.61009  10.17726  1.000 19.92818 ? 206 LYS F N      1 
ATOM   1609 C CA     . LYS C 3 42 ? 12.71648  9.80209   9.19278   1.000 19.44717 ? 206 LYS F CA     1 
ATOM   1610 C C      . LYS C 3 42 ? 11.28437  10.28011  8.95791   1.000 19.25941 ? 206 LYS F C      1 
ATOM   1611 O O      . LYS C 3 42 ? 10.74069  10.07046  7.86609   1.000 18.72787 ? 206 LYS F O      1 
ATOM   1612 C CB     . LYS C 3 42 ? 12.73989  8.32923   9.59489   1.000 18.53328 ? 206 LYS F CB     1 
ATOM   1613 C CG     . LYS C 3 42 ? 12.07871  8.00910   10.91621  1.000 18.49245 ? 206 LYS F CG     1 
ATOM   1614 C CD     . LYS C 3 42 ? 12.48021  6.62327   11.41097  1.000 20.32259 ? 206 LYS F CD     1 
ATOM   1615 C CE     . LYS C 3 42 ? 11.72879  6.18294   12.66818  1.000 21.16015 ? 206 LYS F CE     1 
ATOM   1616 N NZ     . LYS C 3 42 ? 11.86920  7.08453   13.83299  1.000 23.03925 ? 206 LYS F NZ     1 
ATOM   1617 H H      . LYS C 3 42 ? 13.58612  10.21750  10.92628  1.000 23.91381 ? 206 LYS F H      1 
ATOM   1618 H HA     . LYS C 3 42 ? 13.18233  9.88539   8.34605   1.000 23.33661 ? 206 LYS F HA     1 
ATOM   1619 H HB2    . LYS C 3 42 ? 12.28081  7.81806   8.91017   1.000 22.23994 ? 206 LYS F HB2    1 
ATOM   1620 H HB3    . LYS C 3 42 ? 13.66492  8.04410   9.65753   1.000 22.23994 ? 206 LYS F HB3    1 
ATOM   1621 H HG2    . LYS C 3 42 ? 12.35101  8.66206   11.57983  1.000 22.19094 ? 206 LYS F HG2    1 
ATOM   1622 H HG3    . LYS C 3 42 ? 11.11498  8.02834   10.80779  1.000 22.19094 ? 206 LYS F HG3    1 
ATOM   1623 H HD2    . LYS C 3 42 ? 12.29536  5.97540   10.71311  1.000 24.38711 ? 206 LYS F HD2    1 
ATOM   1624 H HD3    . LYS C 3 42 ? 13.42784  6.62657   11.61804  1.000 24.38711 ? 206 LYS F HD3    1 
ATOM   1625 H HE2    . LYS C 3 42 ? 10.78361  6.12748   12.45736  1.000 25.39218 ? 206 LYS F HE2    1 
ATOM   1626 H HE3    . LYS C 3 42 ? 12.06089  5.31149   12.93499  1.000 25.39218 ? 206 LYS F HE3    1 
ATOM   1627 H HZ1    . LYS C 3 42 ? 11.48012  7.86637   13.66140  1.000 27.64710 ? 206 LYS F HZ1    1 
ATOM   1628 H HZ2    . LYS C 3 42 ? 11.48351  6.72067   14.54779  1.000 27.64710 ? 206 LYS F HZ2    1 
ATOM   1629 H HZ3    . LYS C 3 42 ? 12.73064  7.22298   14.00865  1.000 27.64710 ? 206 LYS F HZ3    1 
ATOM   1630 N N      . GLU C 3 43 ? 10.63939  10.89835  9.95427   1.000 19.12202 ? 207 GLU F N      1 
ATOM   1631 C CA     . GLU C 3 43 ? 9.24494   11.29729  9.76696   1.000 19.34615 ? 207 GLU F CA     1 
ATOM   1632 C C      . GLU C 3 43 ? 9.10077   12.35639  8.67615   1.000 19.01090 ? 207 GLU F C      1 
ATOM   1633 O O      . GLU C 3 43 ? 8.12182   12.34348  7.92519   1.000 19.63763 ? 207 GLU F O      1 
ATOM   1634 C CB     . GLU C 3 43 ? 8.62251   11.75703  11.08812  1.000 23.37864 ? 207 GLU F CB     1 
ATOM   1635 C CG     . GLU C 3 43 ? 8.49547   10.65119  12.14852  1.000 29.69629 ? 207 GLU F CG     1 
ATOM   1636 C CD     . GLU C 3 43 ? 7.52549   9.52492   11.76985  1.000 34.45612 ? 207 GLU F CD     1 
ATOM   1637 O OE1    . GLU C 3 43 ? 6.75757   9.69206   10.81103  1.000 29.97295 ? 207 GLU F OE1    1 
ATOM   1638 O OE2    . GLU C 3 43 ? 7.51929   8.47166   12.44545  1.000 39.77092 ? 207 GLU F OE2    1 
ATOM   1639 H H      . GLU C 3 43 ? 10.97644  11.09111  10.72163  1.000 22.94642 ? 207 GLU F H      1 
ATOM   1640 H HA     . GLU C 3 43 ? 8.74368   10.51846  9.47875   1.000 23.21538 ? 207 GLU F HA     1 
ATOM   1641 H HB2    . GLU C 3 43 ? 9.17564   12.46045  11.46248  1.000 28.05437 ? 207 GLU F HB2    1 
ATOM   1642 H HB3    . GLU C 3 43 ? 7.73135   12.09564  10.90899  1.000 28.05437 ? 207 GLU F HB3    1 
ATOM   1643 H HG2    . GLU C 3 43 ? 9.36874   10.25242  12.28741  1.000 35.63554 ? 207 GLU F HG2    1 
ATOM   1644 H HG3    . GLU C 3 43 ? 8.17683   11.04799  12.97429  1.000 35.63554 ? 207 GLU F HG3    1 
ATOM   1645 N N      . ALA C 3 44 ? 10.06366  13.27781  8.55582   1.000 20.23553 ? 208 ALA F N      1 
ATOM   1646 C CA     . ALA C 3 44 ? 9.98625   14.26693  7.48302   1.000 20.62112 ? 208 ALA F CA     1 
ATOM   1647 C C      . ALA C 3 44 ? 9.99320   13.59273  6.11465   1.000 19.35320 ? 208 ALA F C      1 
ATOM   1648 O O      . ALA C 3 44 ? 9.30278   14.03152  5.18667   1.000 20.73070 ? 208 ALA F O      1 
ATOM   1649 C CB     . ALA C 3 44 ? 11.13884  15.26271  7.60287   1.000 22.67901 ? 208 ALA F CB     1 
ATOM   1650 H H      . ALA C 3 44 ? 10.75087  13.34791  9.06809   1.000 24.28264 ? 208 ALA F H      1 
ATOM   1651 H HA     . ALA C 3 44 ? 9.15651   14.76186  7.56950   1.000 24.74535 ? 208 ALA F HA     1 
ATOM   1652 H HB1    . ALA C 3 44 ? 11.05627  15.92729  6.90115   1.000 27.21481 ? 208 ALA F HB1    1 
ATOM   1653 H HB2    . ALA C 3 44 ? 11.09625  15.69198  8.47167   1.000 27.21481 ? 208 ALA F HB2    1 
ATOM   1654 H HB3    . ALA C 3 44 ? 11.97869  14.78632  7.51012   1.000 27.21481 ? 208 ALA F HB3    1 
ATOM   1655 N N      . LEU C 3 45 ? 10.76711  12.51887  5.96873   1.000 18.91430 ? 209 LEU F N      1 
ATOM   1656 C CA     . LEU C 3 45 ? 10.80690  11.79783  4.70244   1.000 17.66288 ? 209 LEU F CA     1 
ATOM   1657 C C      . LEU C 3 45 ? 9.48313   11.08349  4.45533   1.000 17.58766 ? 209 LEU F C      1 
ATOM   1658 O O      . LEU C 3 45 ? 8.94791   11.11188  3.33975   1.000 17.47812 ? 209 LEU F O      1 
ATOM   1659 C CB     . LEU C 3 45 ? 12.00150  10.83328  4.72791   1.000 17.52024 ? 209 LEU F CB     1 
ATOM   1660 C CG     . LEU C 3 45 ? 12.25539  9.97819   3.48190   1.000 17.18647 ? 209 LEU F CG     1 
ATOM   1661 C CD1    . LEU C 3 45 ? 13.72692  9.58686   3.43362   1.000 19.59787 ? 209 LEU F CD1    1 
ATOM   1662 C CD2    . LEU C 3 45 ? 11.37792  8.74847   3.44386   1.000 19.86708 ? 209 LEU F CD2    1 
ATOM   1663 H H      . LEU C 3 45 ? 11.27347  12.19095  6.58165   1.000 22.69716 ? 209 LEU F H      1 
ATOM   1664 H HA     . LEU C 3 45 ? 10.93945  12.40548  3.95807   1.000 21.19546 ? 209 LEU F HA     1 
ATOM   1665 H HB2    . LEU C 3 45 ? 12.80311  11.35962  4.87382   1.000 21.02429 ? 209 LEU F HB2    1 
ATOM   1666 H HB3    . LEU C 3 45 ? 11.86919  10.21861  5.46655   1.000 21.02429 ? 209 LEU F HB3    1 
ATOM   1667 H HG     . LEU C 3 45 ? 12.03123  10.49972  2.69535   1.000 20.62377 ? 209 LEU F HG     1 
ATOM   1668 H HD11   . LEU C 3 45 ? 13.87742  9.01859   2.66205   1.000 23.51744 ? 209 LEU F HD11   1 
ATOM   1669 H HD12   . LEU C 3 45 ? 14.26527  10.39061  3.36252   1.000 23.51744 ? 209 LEU F HD12   1 
ATOM   1670 H HD13   . LEU C 3 45 ? 13.95317  9.10800   4.24628   1.000 23.51744 ? 209 LEU F HD13   1 
ATOM   1671 H HD21   . LEU C 3 45 ? 11.75550  8.11031   2.81849   1.000 23.84050 ? 209 LEU F HD21   1 
ATOM   1672 H HD22   . LEU C 3 45 ? 11.34087  8.35936   4.33162   1.000 23.84050 ? 209 LEU F HD22   1 
ATOM   1673 H HD23   . LEU C 3 45 ? 10.48726  9.00478   3.15762   1.000 23.84050 ? 209 LEU F HD23   1 
ATOM   1674 N N      . ALA C 3 46 ? 8.92876   10.44807  5.48469   1.000 17.86638 ? 210 ALA F N      1 
ATOM   1675 C CA     . ALA C 3 46 ? 7.62314   9.80652   5.35303   1.000 18.12417 ? 210 ALA F CA     1 
ATOM   1676 C C      . ALA C 3 46 ? 6.56141   10.82229  4.95708   1.000 19.03856 ? 210 ALA F C      1 
ATOM   1677 O O      . ALA C 3 46 ? 5.71609   10.55210  4.09543   1.000 19.35009 ? 210 ALA F O      1 
ATOM   1678 C CB     . ALA C 3 46 ? 7.25428   9.10850   6.66161   1.000 18.60999 ? 210 ALA F CB     1 
ATOM   1679 H H      . ALA C 3 46 ? 9.28385   10.37370  6.26442   1.000 21.43965 ? 210 ALA F H      1 
ATOM   1680 H HA     . ALA C 3 46 ? 7.66369   9.12997   4.65910   1.000 21.74901 ? 210 ALA F HA     1 
ATOM   1681 H HB1    . ALA C 3 46 ? 6.38339   8.69286   6.56324   1.000 22.33199 ? 210 ALA F HB1    1 
ATOM   1682 H HB2    . ALA C 3 46 ? 7.92252   8.43361   6.85879   1.000 22.33199 ? 210 ALA F HB2    1 
ATOM   1683 H HB3    . ALA C 3 46 ? 7.22829   9.76631   7.37400   1.000 22.33199 ? 210 ALA F HB3    1 
ATOM   1684 N N      . HIS C 3 47 ? 6.58334   12.00446  5.57858   1.000 19.77283 ? 211 HIS F N      1 
ATOM   1685 C CA     . HIS C 3 47 ? 5.61910   13.03285  5.20022   1.000 20.86011 ? 211 HIS F CA     1 
ATOM   1686 C C      . HIS C 3 47 ? 5.71719   13.34764  3.71610   1.000 21.14831 ? 211 HIS F C      1 
ATOM   1687 O O      . HIS C 3 47 ? 4.69184   13.48101  3.03285   1.000 23.77003 ? 211 HIS F O      1 
ATOM   1688 C CB     . HIS C 3 47 ? 5.83406   14.30140  6.03255   1.000 23.22679 ? 211 HIS F CB     1 
ATOM   1689 C CG     . HIS C 3 47 ? 5.52970   14.13325  7.48793   1.000 24.56006 ? 211 HIS F CG     1 
ATOM   1690 N ND1    . HIS C 3 47 ? 6.02842   14.98208  8.45471   1.000 25.83643 ? 211 HIS F ND1    1 
ATOM   1691 C CD2    . HIS C 3 47 ? 4.76864   13.22486  8.14328   1.000 26.44193 ? 211 HIS F CD2    1 
ATOM   1692 C CE1    . HIS C 3 47 ? 5.59963   14.59440  9.64225   1.000 26.98712 ? 211 HIS F CE1    1 
ATOM   1693 N NE2    . HIS C 3 47 ? 4.83175   13.53212  9.48200   1.000 28.44909 ? 211 HIS F NE2    1 
ATOM   1694 H H      . HIS C 3 47 ? 7.13044   12.22774  6.20342   1.000 23.72740 ? 211 HIS F H      1 
ATOM   1695 H HA     . HIS C 3 47 ? 4.72529   12.70553  5.38694   1.000 25.03213 ? 211 HIS F HA     1 
ATOM   1696 H HB2    . HIS C 3 47 ? 6.76261   14.57085  5.95454   1.000 27.87215 ? 211 HIS F HB2    1 
ATOM   1697 H HB3    . HIS C 3 47 ? 5.25581   15.00036  5.68906   1.000 27.87215 ? 211 HIS F HB3    1 
ATOM   1698 H HD1    . HIS C 3 47 ? 6.53892   15.65823  8.30703   1.000 31.00371 ? 211 HIS F HD1    1 
ATOM   1699 H HD2    . HIS C 3 47 ? 4.29238   12.52424  7.75962   1.000 31.73032 ? 211 HIS F HD2    1 
ATOM   1700 H HE1    . HIS C 3 47 ? 5.80383   15.00058  10.45355  1.000 32.38454 ? 211 HIS F HE1    1 
ATOM   1701 N N      . ARG C 3 48 ? 6.94294   13.44990  3.19535   1.000 20.48968 ? 212 ARG F N      1 
ATOM   1702 C CA     A ARG C 3 48 ? 7.13098   13.76492  1.78621   0.453 21.77428 ? 212 ARG F CA     1 
ATOM   1703 C CA     B ARG C 3 48 ? 7.13064   13.76507  1.78618   0.547 21.11904 ? 212 ARG F CA     1 
ATOM   1704 C C      . ARG C 3 48 ? 6.55634   12.67490  0.89291   1.000 19.92964 ? 212 ARG F C      1 
ATOM   1705 O O      . ARG C 3 48 ? 5.95149   12.97090  -0.14218  1.000 21.78789 ? 212 ARG F O      1 
ATOM   1706 C CB     A ARG C 3 48 ? 8.61521   13.96890  1.49484   0.453 24.55173 ? 212 ARG F CB     1 
ATOM   1707 C CB     B ARG C 3 48 ? 8.61165   13.97678  1.48396   0.547 23.18294 ? 212 ARG F CB     1 
ATOM   1708 C CG     A ARG C 3 48 ? 8.94291   14.20507  0.02928   0.453 26.31858 ? 212 ARG F CG     1 
ATOM   1709 C CG     B ARG C 3 48 ? 8.88315   14.38749  0.04716   0.547 23.83744 ? 212 ARG F CG     1 
ATOM   1710 C CD     A ARG C 3 48 ? 10.38987  14.61350  -0.14989  0.453 29.82396 ? 212 ARG F CD     1 
ATOM   1711 C CD     B ARG C 3 48 ? 10.34008  14.70562  -0.21934  0.547 28.03994 ? 212 ARG F CD     1 
ATOM   1712 N NE     A ARG C 3 48 ? 10.77009  14.72332  -1.55381  0.453 31.82085 ? 212 ARG F NE     1 
ATOM   1713 N NE     B ARG C 3 48 ? 10.79862  15.88687  0.50620   0.547 30.96128 ? 212 ARG F NE     1 
ATOM   1714 C CZ     A ARG C 3 48 ? 11.92348  15.22076  -1.97925  0.453 32.83604 ? 212 ARG F CZ     1 
ATOM   1715 C CZ     B ARG C 3 48 ? 11.92701  16.53399  0.25094   0.547 32.82928 ? 212 ARG F CZ     1 
ATOM   1716 N NH1    A ARG C 3 48 ? 12.82129  15.70372  -1.13678  0.453 34.32933 ? 212 ARG F NH1    1 
ATOM   1717 N NH1    B ARG C 3 48 ? 12.70016  16.19911  -0.76809  0.547 34.15796 ? 212 ARG F NH1    1 
ATOM   1718 N NH2    A ARG C 3 48 ? 12.18644  15.22706  -3.28237  0.453 31.26559 ? 212 ARG F NH2    1 
ATOM   1719 N NH2    B ARG C 3 48 ? 12.29301  17.53534  1.04527   0.547 32.37811 ? 212 ARG F NH2    1 
ATOM   1720 H H      . ARG C 3 48 ? 7.67570   13.34241  3.63251   1.000 24.58762 ? 212 ARG F H      1 
ATOM   1721 H HA     . ARG C 3 48 ? 6.66498   14.59149  1.58491   1.000 25.34285 ? 212 ARG F HA     1 
ATOM   1722 H HB2    A ARG C 3 48 ? 8.92438   14.74196  1.99251   0.453 29.46207 ? 212 ARG F HB2    1 
ATOM   1723 H HB2    B ARG C 3 48 ? 8.95216   14.67676  2.06273   0.547 27.81953 ? 212 ARG F HB2    1 
ATOM   1724 H HB3    A ARG C 3 48 ? 9.09758   13.17677  1.77902   0.453 29.46207 ? 212 ARG F HB3    1 
ATOM   1725 H HB3    B ARG C 3 48 ? 9.08672   13.14776  1.65108   0.547 27.81953 ? 212 ARG F HB3    1 
ATOM   1726 H HG2    A ARG C 3 48 ? 8.79148   13.38774  -0.47068  0.453 31.58230 ? 212 ARG F HG2    1 
ATOM   1727 H HG2    B ARG C 3 48 ? 8.62486   13.66126  -0.54171  0.547 28.60492 ? 212 ARG F HG2    1 
ATOM   1728 H HG3    A ARG C 3 48 ? 8.37949   14.91482  -0.31671  0.453 31.58230 ? 212 ARG F HG3    1 
ATOM   1729 H HG3    B ARG C 3 48 ? 8.36349   15.18077  -0.15674  0.547 28.60492 ? 212 ARG F HG3    1 
ATOM   1730 H HD2    A ARG C 3 48 ? 10.52952  15.47770  0.26792   0.453 35.78875 ? 212 ARG F HD2    1 
ATOM   1731 H HD2    B ARG C 3 48 ? 10.88473  13.95246  0.05818   0.547 33.64792 ? 212 ARG F HD2    1 
ATOM   1732 H HD3    A ARG C 3 48 ? 10.96090  13.94822  0.26511   0.453 35.78875 ? 212 ARG F HD3    1 
ATOM   1733 H HD3    B ARG C 3 48 ? 10.46010  14.87025  -1.16770  0.547 33.64792 ? 212 ARG F HD3    1 
ATOM   1734 H HE     A ARG C 3 48 ? 10.20938  14.44730  -2.14459  0.453 38.18502 ? 212 ARG F HE     1 
ATOM   1735 H HE     B ARG C 3 48 ? 10.30242  16.18321  1.14304   0.547 37.15354 ? 212 ARG F HE     1 
ATOM   1736 H HH11   A ARG C 3 48 ? 12.66349  15.69988  -0.29139  0.453 41.19519 ? 212 ARG F HH11   1 
ATOM   1737 H HH11   B ARG C 3 48 ? 12.47491  15.54819  -1.28303  0.547 40.98955 ? 212 ARG F HH11   1 
ATOM   1738 H HH12   A ARG C 3 48 ? 13.56291  16.02161  -1.43434  0.453 41.19519 ? 212 ARG F HH12   1 
ATOM   1739 H HH12   B ARG C 3 48 ? 13.42828  16.63222  -0.91594  0.547 40.98955 ? 212 ARG F HH12   1 
ATOM   1740 H HH21   A ARG C 3 48 ? 11.61168  14.91097  -3.83856  0.453 37.51871 ? 212 ARG F HH21   1 
ATOM   1741 H HH21   B ARG C 3 48 ? 11.79983  17.75568  1.71447   0.547 38.85374 ? 212 ARG F HH21   1 
ATOM   1742 H HH22   A ARG C 3 48 ? 12.93130  15.54724  -3.56919  0.453 37.51871 ? 212 ARG F HH22   1 
ATOM   1743 H HH22   B ARG C 3 48 ? 13.02294  17.96273  0.88989   0.547 38.85374 ? 212 ARG F HH22   1 
ATOM   1744 N N      . TRP C 3 49 ? 6.74631   11.41025  1.27146   1.000 18.88210 ? 213 TRP F N      1 
ATOM   1745 C CA     . TRP C 3 49 ? 6.18197   10.30270  0.50270   1.000 18.69467 ? 213 TRP F CA     1 
ATOM   1746 C C      . TRP C 3 49 ? 4.66651   10.43471  0.37810   1.000 19.61735 ? 213 TRP F C      1 
ATOM   1747 O O      . TRP C 3 49 ? 4.10846   10.33153  -0.71969  1.000 20.14526 ? 213 TRP F O      1 
ATOM   1748 C CB     . TRP C 3 49 ? 6.57671   8.97641   1.15672   1.000 18.19338 ? 213 TRP F CB     1 
ATOM   1749 C CG     . TRP C 3 49 ? 5.84084   7.76762   0.64406   1.000 17.32023 ? 213 TRP F CG     1 
ATOM   1750 C CD1    . TRP C 3 49 ? 5.12522   6.88588   1.38721   1.000 17.28276 ? 213 TRP F CD1    1 
ATOM   1751 C CD2    . TRP C 3 49 ? 5.77947   7.29279   -0.71682  1.000 16.61091 ? 213 TRP F CD2    1 
ATOM   1752 N NE1    . TRP C 3 49 ? 4.60910   5.89298   0.58289   1.000 17.12582 ? 213 TRP F NE1    1 
ATOM   1753 C CE2    . TRP C 3 49 ? 4.99880   6.11881   -0.71237  1.000 17.12370 ? 213 TRP F CE2    1 
ATOM   1754 C CE3    . TRP C 3 49 ? 6.30748   7.74328   -1.92809  1.000 17.99533 ? 213 TRP F CE3    1 
ATOM   1755 C CZ2    . TRP C 3 49 ? 4.70645   5.41464   -1.86666  1.000 18.78767 ? 213 TRP F CZ2    1 
ATOM   1756 C CZ3    . TRP C 3 49 ? 6.02091   7.03131   -3.07642  1.000 18.86865 ? 213 TRP F CZ3    1 
ATOM   1757 C CH2    . TRP C 3 49 ? 5.24307   5.87511   -3.03295  1.000 19.21927 ? 213 TRP F CH2    1 
ATOM   1758 H H      . TRP C 3 49 ? 7.19468   11.16830  1.96430   1.000 22.65852 ? 213 TRP F H      1 
ATOM   1759 H HA     . TRP C 3 49 ? 6.54706   10.31400  -0.39590  1.000 22.43361 ? 213 TRP F HA     1 
ATOM   1760 H HB2    . TRP C 3 49 ? 7.52263   8.82762   1.00182   1.000 21.83206 ? 213 TRP F HB2    1 
ATOM   1761 H HB3    . TRP C 3 49 ? 6.40243   9.04008   2.10880   1.000 21.83206 ? 213 TRP F HB3    1 
ATOM   1762 H HD1    . TRP C 3 49 ? 5.00098   6.94343   2.30708   1.000 20.73932 ? 213 TRP F HD1    1 
ATOM   1763 H HE1    . TRP C 3 49 ? 4.12113   5.23723   0.85024   1.000 20.55099 ? 213 TRP F HE1    1 
ATOM   1764 H HE3    . TRP C 3 49 ? 6.83984   8.50513   -1.96103  1.000 21.59440 ? 213 TRP F HE3    1 
ATOM   1765 H HZ2    . TRP C 3 49 ? 4.16598   4.65803   -1.84815  1.000 22.54520 ? 213 TRP F HZ2    1 
ATOM   1766 H HZ3    . TRP C 3 49 ? 6.35262   7.32837   -3.89290  1.000 22.64237 ? 213 TRP F HZ3    1 
ATOM   1767 H HH2    . TRP C 3 49 ? 5.08593   5.40538   -3.82007  1.000 23.06312 ? 213 TRP F HH2    1 
ATOM   1768 N N      . GLY C 3 50 ? 3.98227   10.67810  1.49648   1.000 20.14388 ? 214 GLY F N      1 
ATOM   1769 C CA     . GLY C 3 50 ? 2.53013   10.75040  1.45201   1.000 23.25277 ? 214 GLY F CA     1 
ATOM   1770 C C      . GLY C 3 50 ? 2.02872   11.91786  0.62894   1.000 24.72669 ? 214 GLY F C      1 
ATOM   1771 O O      . GLY C 3 50 ? 1.01315   11.81033  -0.06352  1.000 25.09348 ? 214 GLY F O      1 
ATOM   1772 H H      . GLY C 3 50 ? 4.32900   10.80169  2.27372   1.000 24.17266 ? 214 GLY F H      1 
ATOM   1773 H HA2    . GLY C 3 50 ? 2.18090   9.93251   1.06471   1.000 27.90332 ? 214 GLY F HA2    1 
ATOM   1774 H HA3    . GLY C 3 50 ? 2.18680   10.84424  2.35435   1.000 27.90332 ? 214 GLY F HA3    1 
ATOM   1775 N N      . ILE C 3 51 ? 2.70629   13.06317  0.72302   1.000 24.51746 ? 215 ILE F N      1 
ATOM   1776 C CA     . ILE C 3 51 ? 2.31151   14.21995  -0.06914  1.000 27.69077 ? 215 ILE F CA     1 
ATOM   1777 C C      . ILE C 3 51 ? 2.54440   13.95102  -1.55029  1.000 27.71283 ? 215 ILE F C      1 
ATOM   1778 O O      . ILE C 3 51 ? 1.71162   14.30447  -2.39549  1.000 28.63247 ? 215 ILE F O      1 
ATOM   1779 C CB     . ILE C 3 51 ? 3.05216   15.47006  0.43816   1.000 29.04146 ? 215 ILE F CB     1 
ATOM   1780 C CG1    . ILE C 3 51 ? 2.49107   15.86097  1.80396   1.000 31.63904 ? 215 ILE F CG1    1 
ATOM   1781 C CG2    . ILE C 3 51 ? 2.95526   16.61342  -0.56602  1.000 31.36847 ? 215 ILE F CG2    1 
ATOM   1782 C CD1    . ILE C 3 51 ? 3.20263   17.00829  2.45075   1.000 32.99186 ? 215 ILE F CD1    1 
ATOM   1783 H H      . ILE C 3 51 ? 3.38792   13.19206  1.23131   1.000 29.42095 ? 215 ILE F H      1 
ATOM   1784 H HA     . ILE C 3 51 ? 1.36124   14.38041  0.04105   1.000 33.22892 ? 215 ILE F HA     1 
ATOM   1785 H HB     . ILE C 3 51 ? 3.99559   15.26671  0.53549   1.000 34.84975 ? 215 ILE F HB     1 
ATOM   1786 H HG12   . ILE C 3 51 ? 1.56075   16.11381  1.69684   1.000 37.96685 ? 215 ILE F HG12   1 
ATOM   1787 H HG13   . ILE C 3 51 ? 2.56110   15.09780  2.39858   1.000 37.96685 ? 215 ILE F HG13   1 
ATOM   1788 H HG21   . ILE C 3 51 ? 3.24866   17.43384  -0.13973  1.000 37.64216 ? 215 ILE F HG21   1 
ATOM   1789 H HG22   . ILE C 3 51 ? 3.52320   16.41453  -1.32681  1.000 37.64216 ? 215 ILE F HG22   1 
ATOM   1790 H HG23   . ILE C 3 51 ? 2.03372   16.70228  -0.85545  1.000 37.64216 ? 215 ILE F HG23   1 
ATOM   1791 H HD11   . ILE C 3 51 ? 2.92936   17.06616  3.37966   1.000 39.59023 ? 215 ILE F HD11   1 
ATOM   1792 H HD12   . ILE C 3 51 ? 4.15933   16.85777  2.39617   1.000 39.59023 ? 215 ILE F HD12   1 
ATOM   1793 H HD13   . ILE C 3 51 ? 2.96954   17.82704  1.98576   1.000 39.59023 ? 215 ILE F HD13   1 
ATOM   1794 N N      . GLN C 3 52 ? 3.65313   13.27824  -1.88512  1.000 27.17338 ? 216 GLN F N      1 
ATOM   1795 C CA     . GLN C 3 52 ? 3.91464   12.95832  -3.28493  1.000 27.72793 ? 216 GLN F CA     1 
ATOM   1796 C C      . GLN C 3 52 ? 2.83046   12.04172  -3.84187  1.000 25.56955 ? 216 GLN F C      1 
ATOM   1797 O O      . GLN C 3 52 ? 2.43089   12.16990  -5.00926  0.989 27.25567 ? 216 GLN F O      1 
ATOM   1798 C CB     . GLN C 3 52 ? 5.30524   12.33601  -3.44565  1.000 29.85997 ? 216 GLN F CB     1 
ATOM   1799 C CG     . GLN C 3 52 ? 5.72566   12.18069  -4.90774  0.634 31.78526 ? 216 GLN F CG     1 
ATOM   1800 C CD     . GLN C 3 52 ? 7.20879   11.91038  -5.08820  0.838 35.06144 ? 216 GLN F CD     1 
ATOM   1801 O OE1    . GLN C 3 52 ? 7.60161   11.05068  -5.87852  0.432 36.76768 ? 216 GLN F OE1    1 
ATOM   1802 N NE2    . GLN C 3 52 ? 8.04011   12.65479  -4.37373  0.785 35.95124 ? 216 GLN F NE2    1 
ATOM   1803 H H      . GLN C 3 52 ? 4.25225   13.00426  -1.33231  1.000 32.60806 ? 216 GLN F H      1 
ATOM   1804 H HA     . GLN C 3 52 ? 3.90997   13.77878  -3.80235  0.293 33.27352 ? 216 GLN F HA     1 
ATOM   1805 H HB2    . GLN C 3 52 ? 5.95689   12.90400  -3.00561  1.000 35.83196 ? 216 GLN F HB2    1 
ATOM   1806 H HB3    . GLN C 3 52 ? 5.30467   11.45525  -3.03925  1.000 35.83196 ? 216 GLN F HB3    1 
ATOM   1807 H HG2    . GLN C 3 52 ? 5.23941   11.43643  -5.29574  1.000 38.14232 ? 216 GLN F HG2    1 
ATOM   1808 H HG3    . GLN C 3 52 ? 5.51364   12.99932  -5.38291  1.000 38.14232 ? 216 GLN F HG3    1 
ATOM   1809 H HE21   . GLN C 3 52 ? 7.73044   13.25485  -3.84116  1.000 43.14149 ? 216 GLN F HE21   1 
ATOM   1810 H HE22   . GLN C 3 52 ? 8.88934   12.53789  -4.44259  0.215 43.14149 ? 216 GLN F HE22   1 
ATOM   1811 N N      . LYS C 3 53 ? 2.31787   11.12838  -3.01031  1.000 24.68515 ? 217 LYS F N      1 
ATOM   1812 C CA     . LYS C 3 53 ? 1.26488   10.20366  -3.42280  1.000 23.86391 ? 217 LYS F CA     1 
ATOM   1813 C C      . LYS C 3 53 ? -0.12449  10.82054  -3.40533  1.000 25.79205 ? 217 LYS F C      1 
ATOM   1814 O O      . LYS C 3 53 ? -1.03927  10.24670  -4.00253  1.000 27.27733 ? 217 LYS F O      1 
ATOM   1815 C CB     . LYS C 3 53 ? 1.26102   8.98995   -2.49562  1.000 23.39754 ? 217 LYS F CB     1 
ATOM   1816 C CG     . LYS C 3 53 ? 2.36945   7.98685   -2.80501  1.000 23.11536 ? 217 LYS F CG     1 
ATOM   1817 C CD     . LYS C 3 53 ? 2.15689   7.28934   -4.14838  1.000 22.36010 ? 217 LYS F CD     1 
ATOM   1818 C CE     . LYS C 3 53 ? 0.90494   6.42114   -4.17239  1.000 22.78944 ? 217 LYS F CE     1 
ATOM   1819 N NZ     . LYS C 3 53 ? 1.00961   5.28640   -3.23211  1.000 21.91494 ? 217 LYS F NZ     1 
ATOM   1820 H H      . LYS C 3 53 ? 2.56720   11.02482  -2.19379  1.000 29.62217 ? 217 LYS F H      1 
ATOM   1821 H HA     . LYS C 3 53 ? 1.45431   9.91931   -4.33063  1.000 28.63669 ? 217 LYS F HA     1 
ATOM   1822 H HB2    . LYS C 3 53 ? 1.38067   9.29337   -1.58210  1.000 28.07705 ? 217 LYS F HB2    1 
ATOM   1823 H HB3    . LYS C 3 53 ? 0.41106   8.53099   -2.58412  1.000 28.07705 ? 217 LYS F HB3    1 
ATOM   1824 H HG2    . LYS C 3 53 ? 3.22022   8.45167   -2.83723  1.000 27.73843 ? 217 LYS F HG2    1 
ATOM   1825 H HG3    . LYS C 3 53 ? 2.38808   7.30845   -2.11196  1.000 27.73843 ? 217 LYS F HG3    1 
ATOM   1826 H HD2    . LYS C 3 53 ? 2.06869   7.96080   -4.84283  1.000 26.83212 ? 217 LYS F HD2    1 
ATOM   1827 H HD3    . LYS C 3 53 ? 2.91979   6.71941   -4.33293  1.000 26.83212 ? 217 LYS F HD3    1 
ATOM   1828 H HE2    . LYS C 3 53 ? 0.13801   6.95764   -3.91767  1.000 27.34733 ? 217 LYS F HE2    1 
ATOM   1829 H HE3    . LYS C 3 53 ? 0.77885   6.06529   -5.06590  1.000 27.34733 ? 217 LYS F HE3    1 
ATOM   1830 H HZ1    . LYS C 3 53 ? 0.25237   4.81875   -3.23391  1.000 26.29793 ? 217 LYS F HZ1    1 
ATOM   1831 H HZ2    . LYS C 3 53 ? 1.67951   4.75227   -3.47300  1.000 26.29793 ? 217 LYS F HZ2    1 
ATOM   1832 H HZ3    . LYS C 3 53 ? 1.16163   5.58678   -2.40824  1.000 26.29793 ? 217 LYS F HZ3    1 
ATOM   1833 N N      . GLY C 3 54 ? -0.31355  11.94675  -2.72406  1.000 26.81296 ? 218 GLY F N      1 
ATOM   1834 C CA     . GLY C 3 54 ? -1.63935  12.52563  -2.61222  1.000 27.96537 ? 218 GLY F CA     1 
ATOM   1835 C C      . GLY C 3 54 ? -2.57161  11.74428  -1.71134  1.000 28.86871 ? 218 GLY F C      1 
ATOM   1836 O O      . GLY C 3 54 ? -3.78772  11.75814  -1.91991  1.000 29.71073 ? 218 GLY F O      1 
ATOM   1837 H H      . GLY C 3 54 ? 0.30563   12.38828  -2.32248  1.000 32.17555 ? 218 GLY F H      1 
ATOM   1838 H HA2    . GLY C 3 54 ? -1.56168  13.42480  -2.25674  1.000 33.55844 ? 218 GLY F HA2    1 
ATOM   1839 H HA3    . GLY C 3 54 ? -2.04004  12.56838  -3.49455  1.000 33.55844 ? 218 GLY F HA3    1 
ATOM   1840 N N      . ASN C 3 55 ? -2.03367  11.05611  -0.71258  1.000 26.73618 ? 219 ASN F N      1 
ATOM   1841 C CA     . ASN C 3 55 ? -2.85631  10.23154  0.15760   1.000 25.87206 ? 219 ASN F CA     1 
ATOM   1842 C C      . ASN C 3 55 ? -3.74793  11.10408  1.03478   1.000 27.00889 ? 219 ASN F C      1 
ATOM   1843 O O      . ASN C 3 55 ? -3.45788  12.27301  1.29363   1.000 27.49294 ? 219 ASN F O      1 
ATOM   1844 C CB     . ASN C 3 55 ? -1.96522  9.37858   1.05784   1.000 24.93736 ? 219 ASN F CB     1 
ATOM   1845 C CG     . ASN C 3 55 ? -1.17861  8.33060   0.28326   1.000 24.11658 ? 219 ASN F CG     1 
ATOM   1846 O OD1    . ASN C 3 55 ? -1.56677  7.91659   -0.80658  1.000 24.85108 ? 219 ASN F OD1    1 
ATOM   1847 N ND2    . ASN C 3 55 ? -0.06647  7.89888   0.84711   1.000 21.95745 ? 219 ASN F ND2    1 
ATOM   1848 H H      . ASN C 3 55 ? -1.19589  11.05009  -0.51844  1.000 32.08341 ? 219 ASN F H      1 
ATOM   1849 H HA     . ASN C 3 55 ? -3.41707  9.65273   -0.38224  1.000 31.04647 ? 219 ASN F HA     1 
ATOM   1850 H HB2    . ASN C 3 55 ? -1.33087  9.95473   1.51232   1.000 29.92483 ? 219 ASN F HB2    1 
ATOM   1851 H HB3    . ASN C 3 55 ? -2.51973  8.91836   1.70716   1.000 29.92483 ? 219 ASN F HB3    1 
ATOM   1852 H HD21   . ASN C 3 55 ? 0.41485   7.30666   0.45062   1.000 26.34894 ? 219 ASN F HD21   1 
ATOM   1853 H HD22   . ASN C 3 55 ? 0.17705   8.20973   1.61110   1.000 26.34894 ? 219 ASN F HD22   1 
ATOM   1854 N N      . ARG C 3 56 ? -4.84540  10.50788  1.50816   0.987 28.03744 ? 220 ARG F N      1 
ATOM   1855 C CA     . ARG C 3 56 ? -5.83154  11.27481  2.26674   1.000 29.63524 ? 220 ARG F CA     1 
ATOM   1856 C C      . ARG C 3 56 ? -5.29272  11.68024  3.63293   1.000 28.32528 ? 220 ARG F C      1 
ATOM   1857 O O      . ARG C 3 56 ? -5.52254  12.80958  4.08533   0.806 30.34154 ? 220 ARG F O      1 
ATOM   1858 C CB     . ARG C 3 56 ? -7.11455  10.45997  2.42181   1.000 30.44028 ? 220 ARG F CB     1 
ATOM   1859 C CG     . ARG C 3 56 ? -8.14293  11.09155  3.36005   1.000 31.24850 ? 220 ARG F CG     1 
ATOM   1860 C CD     . ARG C 3 56 ? -9.40927  10.25736  3.45559   0.560 33.31260 ? 220 ARG F CD     1 
ATOM   1861 N NE     . ARG C 3 56 ? -9.09080  8.85324   3.67477   0.446 35.36956 ? 220 ARG F NE     1 
ATOM   1862 C CZ     . ARG C 3 56 ? -9.19569  7.89580   2.76262   0.597 37.77356 ? 220 ARG F CZ     1 
ATOM   1863 N NH1    . ARG C 3 56 ? -9.73197  8.12047   1.57159   0.400 39.56395 ? 220 ARG F NH1    1 
ATOM   1864 N NH2    . ARG C 3 56 ? -8.75033  6.67896   3.05244   1.000 38.09958 ? 220 ARG F NH2    1 
ATOM   1865 H H      . ARG C 3 56 ? -5.03836  9.67613   1.40544   1.000 33.64493 ? 220 ARG F H      1 
ATOM   1866 H HA     . ARG C 3 56 ? -6.04020  12.08474  1.77543   1.000 35.56228 ? 220 ARG F HA     1 
ATOM   1867 H HB2    . ARG C 3 56 ? -7.52956  10.36481  1.55025   1.000 36.52833 ? 220 ARG F HB2    1 
ATOM   1868 H HB3    . ARG C 3 56 ? -6.88711  9.58690   2.77807   1.000 36.52833 ? 220 ARG F HB3    1 
ATOM   1869 H HG2    . ARG C 3 56 ? -7.76149  11.16673  4.24873   0.490 37.49820 ? 220 ARG F HG2    1 
ATOM   1870 H HG3    . ARG C 3 56 ? -8.38299  11.97024  3.02663   0.727 37.49820 ? 220 ARG F HG3    1 
ATOM   1871 H HD2    . ARG C 3 56 ? -9.94748  10.57048  4.19935   0.885 39.97512 ? 220 ARG F HD2    1 
ATOM   1872 H HD3    . ARG C 3 56 ? -9.91006  10.33374  2.62837   0.811 39.97512 ? 220 ARG F HD3    1 
ATOM   1873 H HE     . ARG C 3 56 ? -8.81304  8.62714   4.45664   1.000 42.44348 ? 220 ARG F HE     1 
ATOM   1874 H HH11   . ARG C 3 56 ? -10.02378 8.90453   1.37238   1.000 47.47674 ? 220 ARG F HH11   1 
ATOM   1875 H HH12   . ARG C 3 56 ? -9.78813  7.48218   0.99798   1.000 47.47674 ? 220 ARG F HH12   1 
ATOM   1876 H HH21   . ARG C 3 56 ? -8.40029  6.52115   3.82196   0.899 45.71949 ? 220 ARG F HH21   1 
ATOM   1877 H HH22   . ARG C 3 56 ? -8.81192  6.04864   2.47063   0.701 45.71949 ? 220 ARG F HH22   1 
ATOM   1878 N N      . LYS C 3 57 ? -4.59705  10.77274  4.30818   1.000 28.23262 ? 221 LYS F N      1 
ATOM   1879 C CA     . LYS C 3 57 ? -4.06211  11.01213  5.63826   1.000 27.63081 ? 221 LYS F CA     1 
ATOM   1880 C C      . LYS C 3 57 ? -2.57674  11.36633  5.56594   1.000 26.29955 ? 221 LYS F C      1 
ATOM   1881 O O      . LYS C 3 57 ? -1.88453  11.10060  4.57503   1.000 25.88439 ? 221 LYS F O      1 
ATOM   1882 C CB     . LYS C 3 57 ? -4.23074  9.75976   6.50890   1.000 32.32178 ? 221 LYS F CB     1 
ATOM   1883 C CG     . LYS C 3 57 ? -5.63733  9.19386   6.55928   1.000 36.97747 ? 221 LYS F CG     1 
ATOM   1884 C CD     . LYS C 3 57 ? -6.42078  9.76272   7.71803   1.000 44.54025 ? 221 LYS F CD     1 
ATOM   1885 C CE     . LYS C 3 57 ? -7.87129  9.26748   7.69320   1.000 50.53004 ? 221 LYS F CE     1 
ATOM   1886 N NZ     . LYS C 3 57 ? -8.68574  9.76394   8.83254   1.000 54.66559 ? 221 LYS F NZ     1 
ATOM   1887 H H      . LYS C 3 57 ? -4.41764  9.98790   4.00581   1.000 33.87914 ? 221 LYS F H      1 
ATOM   1888 H HA     . LYS C 3 57 ? -4.53942  11.75274  6.04393   1.000 33.15697 ? 221 LYS F HA     1 
ATOM   1889 H HB2    . LYS C 3 57 ? -3.65058  9.06451   6.16112   1.000 38.78613 ? 221 LYS F HB2    1 
ATOM   1890 H HB3    . LYS C 3 57 ? -3.97459  9.98174   7.41775   1.000 38.78613 ? 221 LYS F HB3    1 
ATOM   1891 H HG2    . LYS C 3 57 ? -6.10288  9.41630   5.73789   1.000 44.37296 ? 221 LYS F HG2    1 
ATOM   1892 H HG3    . LYS C 3 57 ? -5.59267  8.23066   6.66491   1.000 44.37296 ? 221 LYS F HG3    1 
ATOM   1893 H HD2    . LYS C 3 57 ? -6.01424  9.48149   8.55262   1.000 53.44830 ? 221 LYS F HD2    1 
ATOM   1894 H HD3    . LYS C 3 57 ? -6.42559  10.73103  7.66107   1.000 53.44830 ? 221 LYS F HD3    1 
ATOM   1895 H HE2    . LYS C 3 57 ? -8.29210  9.57050   6.87344   1.000 60.63605 ? 221 LYS F HE2    1 
ATOM   1896 H HE3    . LYS C 3 57 ? -7.87231  8.29811   7.72796   1.000 60.63605 ? 221 LYS F HE3    1 
ATOM   1897 H HZ1    . LYS C 3 57 ? -9.52140  9.46594   8.76201   1.000 65.59871 ? 221 LYS F HZ1    1 
ATOM   1898 H HZ2    . LYS C 3 57 ? -8.34071  9.47710   9.60116   1.000 65.59871 ? 221 LYS F HZ2    1 
ATOM   1899 H HZ3    . LYS C 3 57 ? -8.69565  10.65388  8.83465   1.000 65.59871 ? 221 LYS F HZ3    1 
ATOM   1900 N N      . LYS C 3 58 ? -2.08519  11.96040  6.65019   1.000 26.62666 ? 222 LYS F N      1 
ATOM   1901 C CA     . LYS C 3 58 ? -0.65480  12.19808  6.79402   1.000 27.92159 ? 222 LYS F CA     1 
ATOM   1902 C C      . LYS C 3 58 ? 0.07701   10.86019  6.84257   1.000 25.06923 ? 222 LYS F C      1 
ATOM   1903 O O      . LYS C 3 58 ? -0.33671  9.94113   7.55801   1.000 25.22383 ? 222 LYS F O      1 
ATOM   1904 C CB     . LYS C 3 58 ? -0.40964  12.97055  8.08841   1.000 32.22653 ? 222 LYS F CB     1 
ATOM   1905 C CG     . LYS C 3 58 ? 1.04444   13.36752  8.32167   1.000 39.33520 ? 222 LYS F CG     1 
ATOM   1906 C CD     . LYS C 3 58 ? 1.23982   13.98088  9.70681   1.000 46.36318 ? 222 LYS F CD     1 
ATOM   1907 C CE     . LYS C 3 58 ? 1.64209   12.92365  10.73284  1.000 52.79960 ? 222 LYS F CE     1 
ATOM   1908 N NZ     . LYS C 3 58 ? 1.51523   13.39461  12.14976  1.000 56.39924 ? 222 LYS F NZ     1 
ATOM   1909 H H      . LYS C 3 58 ? -2.55791  12.23424  7.31437   1.000 31.95199 ? 222 LYS F H      1 
ATOM   1910 H HA     . LYS C 3 58 ? -0.31640  12.71644  6.04723   1.000 33.50591 ? 222 LYS F HA     1 
ATOM   1911 H HB2    . LYS C 3 58 ? -0.93592  13.78507  8.06657   1.000 38.67184 ? 222 LYS F HB2    1 
ATOM   1912 H HB3    . LYS C 3 58 ? -0.68581  12.41706  8.83560   1.000 38.67184 ? 222 LYS F HB3    1 
ATOM   1913 H HG2    . LYS C 3 58 ? 1.60748   12.58054  8.25418   1.000 47.20224 ? 222 LYS F HG2    1 
ATOM   1914 H HG3    . LYS C 3 58 ? 1.30941   14.02295  7.65751   1.000 47.20224 ? 222 LYS F HG3    1 
ATOM   1915 H HD2    . LYS C 3 58 ? 1.94133   14.64958  9.66646   1.000 55.63581 ? 222 LYS F HD2    1 
ATOM   1916 H HD3    . LYS C 3 58 ? 0.40926   14.38853  9.99816   1.000 55.63581 ? 222 LYS F HD3    1 
ATOM   1917 H HE2    . LYS C 3 58 ? 1.07033   12.14752  10.62504  1.000 63.35952 ? 222 LYS F HE2    1 
ATOM   1918 H HE3    . LYS C 3 58 ? 2.56816   12.67685  10.58321  1.000 63.35952 ? 222 LYS F HE3    1 
ATOM   1919 H HZ1    . LYS C 3 58 ? 1.82213   12.77154  12.70626  1.000 67.67909 ? 222 LYS F HZ1    1 
ATOM   1920 H HZ2    . LYS C 3 58 ? 1.98480   14.14176  12.26539  1.000 67.67909 ? 222 LYS F HZ2    1 
ATOM   1921 H HZ3    . LYS C 3 58 ? 0.66144   13.55754  12.34109  1.000 67.67909 ? 222 LYS F HZ3    1 
ATOM   1922 N N      . MET C 3 59 ? 1.15031   10.73630  6.06256   1.000 21.97483 ? 223 MET F N      1 
ATOM   1923 C CA     . MET C 3 59 ? 1.93527   9.51119   6.05626   1.000 21.34745 ? 223 MET F CA     1 
ATOM   1924 C C      . MET C 3 59 ? 2.84093   9.49705   7.28268   1.000 22.96679 ? 223 MET F C      1 
ATOM   1925 O O      . MET C 3 59 ? 3.35078   10.53916  7.70877   1.000 26.86967 ? 223 MET F O      1 
ATOM   1926 C CB     . MET C 3 59 ? 2.77707   9.45540   4.77828   1.000 21.28646 ? 223 MET F CB     1 
ATOM   1927 C CG     . MET C 3 59 ? 3.73621   8.28049   4.64335   1.000 21.18258 ? 223 MET F CG     1 
ATOM   1928 S SD     . MET C 3 59 ? 3.03490   6.62670   4.82965   1.000 19.98545 ? 223 MET F SD     1 
ATOM   1929 C CE     . MET C 3 59 ? 1.88187   6.56158   3.46260   1.000 19.45275 ? 223 MET F CE     1 
ATOM   1930 H H      . MET C 3 59 ? 1.44086   11.34685  5.53113   1.000 26.36979 ? 223 MET F H      1 
ATOM   1931 H HA     . MET C 3 59 ? 1.35842   8.73148   6.07048   1.000 25.61694 ? 223 MET F HA     1 
ATOM   1932 H HB2    . MET C 3 59 ? 2.17190   9.41606   4.02123   1.000 25.54376 ? 223 MET F HB2    1 
ATOM   1933 H HB3    . MET C 3 59 ? 3.31099   10.26405  4.73453   1.000 25.54376 ? 223 MET F HB3    1 
ATOM   1934 H HG2    . MET C 3 59 ? 4.13589   8.31952   3.76038   1.000 25.41910 ? 223 MET F HG2    1 
ATOM   1935 H HG3    . MET C 3 59 ? 4.42239   8.37401   5.32255   1.000 25.41910 ? 223 MET F HG3    1 
ATOM   1936 H HE1    . MET C 3 59 ? 1.56109   5.65158   3.36310   1.000 23.34330 ? 223 MET F HE1    1 
ATOM   1937 H HE2    . MET C 3 59 ? 1.13817   7.15604   3.64815   1.000 23.34330 ? 223 MET F HE2    1 
ATOM   1938 H HE3    . MET C 3 59 ? 2.33593   6.84265   2.65283   1.000 23.34330 ? 223 MET F HE3    1 
ATOM   1939 N N      . THR C 3 60 ? 3.02319   8.31554   7.86330   1.000 21.65359 ? 224 THR F N      1 
ATOM   1940 C CA     . THR C 3 60 ? 3.92426   8.13261   8.99137   1.000 22.13275 ? 224 THR F CA     1 
ATOM   1941 C C      . THR C 3 60 ? 5.01430   7.15557   8.59629   1.000 20.15243 ? 224 THR F C      1 
ATOM   1942 O O      . THR C 3 60 ? 4.86464   6.37857   7.65303   1.000 19.11236 ? 224 THR F O      1 
ATOM   1943 C CB     . THR C 3 60 ? 3.20143   7.54261   10.20888  1.000 23.46958 ? 224 THR F CB     1 
ATOM   1944 O OG1    . THR C 3 60 ? 2.71491   6.23678   9.87652   1.000 23.86232 ? 224 THR F OG1    1 
ATOM   1945 C CG2    . THR C 3 60 ? 2.06715   8.44908   10.66963  1.000 25.17826 ? 224 THR F CG2    1 
ATOM   1946 H H      . THR C 3 60 ? 2.62792   7.59302   7.61565   1.000 25.98431 ? 224 THR F H      1 
ATOM   1947 H HA     . THR C 3 60 ? 4.30271   8.99300   9.23096   1.000 26.55930 ? 224 THR F HA     1 
ATOM   1948 H HB     . THR C 3 60 ? 3.81592   7.46842   10.95574  1.000 28.16350 ? 224 THR F HB     1 
ATOM   1949 H HG1    . THR C 3 60 ? 2.29513   5.91225   10.52772  1.000 28.63478 ? 224 THR F HG1    1 
ATOM   1950 H HG21   . THR C 3 60 ? 1.66488   8.09278   11.47718  1.000 30.21391 ? 224 THR F HG21   1 
ATOM   1951 H HG22   . THR C 3 60 ? 2.40722   9.33873   10.85342  1.000 30.21391 ? 224 THR F HG22   1 
ATOM   1952 H HG23   . THR C 3 60 ? 1.38825   8.50798   9.97931   1.000 30.21391 ? 224 THR F HG23   1 
ATOM   1953 N N      . TYR C 3 61 ? 6.12548   7.19335   9.33484   1.000 19.56456 ? 225 TYR F N      1 
ATOM   1954 C CA     . TYR C 3 61 ? 7.16078   6.20073   9.08496   1.000 18.23587 ? 225 TYR F CA     1 
ATOM   1955 C C      . TYR C 3 61 ? 6.62156   4.78333   9.27253   1.000 18.45987 ? 225 TYR F C      1 
ATOM   1956 O O      . TYR C 3 61 ? 6.97325   3.88411   8.50300   1.000 19.93393 ? 225 TYR F O      1 
ATOM   1957 C CB     . TYR C 3 61 ? 8.41111   6.45730   9.94000   1.000 19.78762 ? 225 TYR F CB     1 
ATOM   1958 C CG     . TYR C 3 61 ? 9.48208   5.44074   9.66397   1.000 20.02184 ? 225 TYR F CG     1 
ATOM   1959 C CD1    . TYR C 3 61 ? 10.31366  5.57740   8.56133   1.000 19.40334 ? 225 TYR F CD1    1 
ATOM   1960 C CD2    . TYR C 3 61 ? 9.62316   4.31304   10.46360  1.000 19.51089 ? 225 TYR F CD2    1 
ATOM   1961 C CE1    . TYR C 3 61 ? 11.27761  4.62836   8.26798   1.000 20.38648 ? 225 TYR F CE1    1 
ATOM   1962 C CE2    . TYR C 3 61 ? 10.58179  3.35121   10.18290  1.000 20.64000 ? 225 TYR F CE2    1 
ATOM   1963 C CZ     . TYR C 3 61 ? 11.40390  3.51311   9.06968   1.000 20.39092 ? 225 TYR F CZ     1 
ATOM   1964 O OH     . TYR C 3 61 ? 12.35411  2.56495   8.78369   1.000 22.72017 ? 225 TYR F OH     1 
ATOM   1965 H H      . TYR C 3 61 ? 6.29417   7.76027   9.95913   1.000 23.47747 ? 225 TYR F H      1 
ATOM   1966 H HA     . TYR C 3 61 ? 7.44877   6.28741   8.16276   1.000 21.88305 ? 225 TYR F HA     1 
ATOM   1967 H HB2    . TYR C 3 61 ? 8.76448   7.33726   9.73582   1.000 23.74514 ? 225 TYR F HB2    1 
ATOM   1968 H HB3    . TYR C 3 61 ? 8.17400   6.40472   10.87911  1.000 23.74514 ? 225 TYR F HB3    1 
ATOM   1969 H HD1    . TYR C 3 61 ? 10.22156  6.32023   8.00941   1.000 23.28401 ? 225 TYR F HD1    1 
ATOM   1970 H HD2    . TYR C 3 61 ? 9.06532   4.20152   11.19932  1.000 23.41307 ? 225 TYR F HD2    1 
ATOM   1971 H HE1    . TYR C 3 61 ? 11.83731  4.74211   7.53402   1.000 24.46378 ? 225 TYR F HE1    1 
ATOM   1972 H HE2    . TYR C 3 61 ? 10.67497  2.60620   10.73170  1.000 24.76800 ? 225 TYR F HE2    1 
ATOM   1973 H HH     . TYR C 3 61 ? 12.27835  1.91448   9.30977   1.000 27.26421 ? 225 TYR F HH     1 
ATOM   1974 N N      . GLN C 3 62 ? 5.77098   4.55245   10.28956  1.000 21.28116 ? 226 GLN F N      1 
ATOM   1975 C CA     A GLN C 3 62 ? 5.23680   3.20833   10.51584  0.530 20.80201 ? 226 GLN F CA     1 
ATOM   1976 C CA     B GLN C 3 62 ? 5.22392   3.21427   10.51589  0.470 22.12280 ? 226 GLN F CA     1 
ATOM   1977 C C      . GLN C 3 62 ? 4.47585   2.70410   9.28557   1.000 21.30170 ? 226 GLN F C      1 
ATOM   1978 O O      . GLN C 3 62 ? 4.66216   1.56087   8.86127   1.000 22.26175 ? 226 GLN F O      1 
ATOM   1979 C CB     A GLN C 3 62 ? 4.35880   3.14854   11.77789  0.530 22.72856 ? 226 GLN F CB     1 
ATOM   1980 C CB     B GLN C 3 62 ? 4.26901   3.21814   11.71715  0.470 25.31552 ? 226 GLN F CB     1 
ATOM   1981 C CG     A GLN C 3 62 ? 5.12626   2.98904   13.12709  0.530 24.44958 ? 226 GLN F CG     1 
ATOM   1982 C CG     B GLN C 3 62 ? 3.68589   1.82176   12.03289  0.470 27.33037 ? 226 GLN F CG     1 
ATOM   1983 C CD     A GLN C 3 62 ? 5.34688   1.52190   13.61247  0.530 26.64429 ? 226 GLN F CD     1 
ATOM   1984 C CD     B GLN C 3 62 ? 2.27878   1.84245   12.63455  0.470 26.34562 ? 226 GLN F CD     1 
ATOM   1985 O OE1    A GLN C 3 62 ? 4.69973   0.56792   13.14919  0.530 26.16575 ? 226 GLN F OE1    1 
ATOM   1986 O OE1    B GLN C 3 62 ? 1.26575   2.10521   11.94328  0.470 22.96316 ? 226 GLN F OE1    1 
ATOM   1987 N NE2    A GLN C 3 62 ? 6.25475   1.35929   14.58150  0.530 28.54524 ? 226 GLN F NE2    1 
ATOM   1988 N NE2    B GLN C 3 62 ? 2.20323   1.52228   13.92639  0.470 25.05657 ? 226 GLN F NE2    1 
ATOM   1989 H H      A GLN C 3 62 ? 5.49675   5.14673   10.84744  0.530 25.53739 ? 226 GLN F H      1 
ATOM   1990 H H      B GLN C 3 62 ? 5.50270   5.14681   10.85023  0.470 25.53739 ? 226 GLN F H      1 
ATOM   1991 H HA     . GLN C 3 62 ? 5.98659   2.61397   10.67540  1.000 26.54736 ? 226 GLN F HA     1 
ATOM   1992 H HB2    A GLN C 3 62 ? 3.84781   3.97121   11.83261  0.530 27.27427 ? 226 GLN F HB2    1 
ATOM   1993 H HB2    B GLN C 3 62 ? 4.75112   3.52497   12.50094  0.470 30.37862 ? 226 GLN F HB2    1 
ATOM   1994 H HB3    A GLN C 3 62 ? 3.75925   2.39041   11.69610  0.530 27.27427 ? 226 GLN F HB3    1 
ATOM   1995 H HB3    B GLN C 3 62 ? 3.52855   3.81555   11.52816  0.470 30.37862 ? 226 GLN F HB3    1 
ATOM   1996 H HG2    A GLN C 3 62 ? 6.00230   3.39373   13.02879  0.530 29.33950 ? 226 GLN F HG2    1 
ATOM   1997 H HG2    B GLN C 3 62 ? 3.64444   1.31049   11.20961  0.470 32.79645 ? 226 GLN F HG2    1 
ATOM   1998 H HG3    A GLN C 3 62 ? 4.62455   3.44795   13.81890  0.530 29.33950 ? 226 GLN F HG3    1 
ATOM   1999 H HG3    B GLN C 3 62 ? 4.26948   1.37948   12.66905  0.470 32.79645 ? 226 GLN F HG3    1 
ATOM   2000 H HE21   A GLN C 3 62 ? 6.67407   2.04080   14.89664  0.530 34.25429 ? 226 GLN F HE21   1 
ATOM   2001 H HE21   B GLN C 3 62 ? 2.91714   1.32270   14.36240  0.470 30.06788 ? 226 GLN F HE21   1 
ATOM   2002 H HE22   A GLN C 3 62 ? 6.41905   0.57325   14.88931  0.530 34.25429 ? 226 GLN F HE22   1 
ATOM   2003 H HE22   B GLN C 3 62 ? 1.44058   1.51531   14.32378  0.470 30.06788 ? 226 GLN F HE22   1 
ATOM   2004 N N      . LYS C 3 63 ? 3.60320   3.53675   8.71332   1.000 21.03797 ? 227 LYS F N      1 
ATOM   2005 C CA     . LYS C 3 63 ? 2.85475   3.09581   7.52981   1.000 20.49553 ? 227 LYS F CA     1 
ATOM   2006 C C      . LYS C 3 63 ? 3.77616   2.88684   6.34355   1.000 18.73079 ? 227 LYS F C      1 
ATOM   2007 O O      . LYS C 3 63 ? 3.60134   1.93143   5.58328   1.000 19.34307 ? 227 LYS F O      1 
ATOM   2008 C CB     . LYS C 3 63 ? 1.76203   4.09077   7.15131   1.000 21.67705 ? 227 LYS F CB     1 
ATOM   2009 C CG     . LYS C 3 63 ? 0.61673   4.11662   8.13255   1.000 23.08980 ? 227 LYS F CG     1 
ATOM   2010 C CD     . LYS C 3 63 ? -0.53355  4.96554   7.63701   1.000 23.93626 ? 227 LYS F CD     1 
ATOM   2011 C CE     . LYS C 3 63 ? -0.15716  6.43774   7.57404   1.000 23.88258 ? 227 LYS F CE     1 
ATOM   2012 N NZ     . LYS C 3 63 ? -1.34637  7.29063   7.26750   1.000 24.31802 ? 227 LYS F NZ     1 
ATOM   2013 H H      . LYS C 3 63 ? 3.42988   4.33587   8.97973   1.000 25.24556 ? 227 LYS F H      1 
ATOM   2014 H HA     . LYS C 3 63 ? 2.42504   2.25652   7.75751   1.000 24.59464 ? 227 LYS F HA     1 
ATOM   2015 H HB2    . LYS C 3 63 ? 2.14598   4.98088   7.11702   1.000 26.01246 ? 227 LYS F HB2    1 
ATOM   2016 H HB3    . LYS C 3 63 ? 1.40518   3.84967   6.28216   1.000 26.01246 ? 227 LYS F HB3    1 
ATOM   2017 H HG2    . LYS C 3 63 ? 0.29051   3.21305   8.26687   1.000 27.70777 ? 227 LYS F HG2    1 
ATOM   2018 H HG3    . LYS C 3 63 ? 0.92547   4.48646   8.97445   1.000 27.70777 ? 227 LYS F HG3    1 
ATOM   2019 H HD2    . LYS C 3 63 ? -0.78434  4.67715   6.74548   1.000 28.72351 ? 227 LYS F HD2    1 
ATOM   2020 H HD3    . LYS C 3 63 ? -1.28658  4.86951   8.24086   1.000 28.72351 ? 227 LYS F HD3    1 
ATOM   2021 H HE2    . LYS C 3 63 ? 0.20477   6.71423   8.43047   1.000 28.65910 ? 227 LYS F HE2    1 
ATOM   2022 H HE3    . LYS C 3 63 ? 0.50306   6.57148   6.87610   1.000 28.65910 ? 227 LYS F HE3    1 
ATOM   2023 H HZ1    . LYS C 3 63 ? -1.67560  7.07801   6.46844   1.000 29.18162 ? 227 LYS F HZ1    1 
ATOM   2024 H HZ2    . LYS C 3 63 ? -1.97740  7.16545   7.88251   1.000 29.18162 ? 227 LYS F HZ2    1 
ATOM   2025 H HZ3    . LYS C 3 63 ? -1.11243  8.14933   7.26433   1.000 29.18162 ? 227 LYS F HZ3    1 
ATOM   2026 N N      . MET C 3 64 ? 4.78509   3.75232   6.19522   1.000 17.61357 ? 228 MET F N      1 
ATOM   2027 C CA     . MET C 3 64 ? 5.74421   3.58164   5.11070   1.000 17.13541 ? 228 MET F CA     1 
ATOM   2028 C C      . MET C 3 64 ? 6.54485   2.29694   5.29560   1.000 17.20022 ? 228 MET F C      1 
ATOM   2029 O O      . MET C 3 64 ? 6.75936   1.54596   4.33469   1.000 17.73477 ? 228 MET F O      1 
ATOM   2030 C CB     . MET C 3 64 ? 6.65429   4.80654   5.00970   1.000 16.53091 ? 228 MET F CB     1 
ATOM   2031 C CG     . MET C 3 64 ? 7.51353   4.82303   3.75302   1.000 17.99290 ? 228 MET F CG     1 
ATOM   2032 S SD     . MET C 3 64 ? 8.69988   6.18701   3.69872   1.000 18.42258 ? 228 MET F SD     1 
ATOM   2033 C CE     . MET C 3 64 ? 9.82339   5.54144   4.93011   1.000 22.50385 ? 228 MET F CE     1 
ATOM   2034 H H      . MET C 3 64 ? 4.93068   4.43238   6.70111   1.000 21.13628 ? 228 MET F H      1 
ATOM   2035 H HA     . MET C 3 64 ? 5.26490   3.52354   4.26940   1.000 20.56249 ? 228 MET F HA     1 
ATOM   2036 H HB2    . MET C 3 64 ? 6.10403   5.60534   5.00394   1.000 19.83709 ? 228 MET F HB2    1 
ATOM   2037 H HB3    . MET C 3 64 ? 7.24861   4.81860   5.77621   1.000 19.83709 ? 228 MET F HB3    1 
ATOM   2038 H HG2    . MET C 3 64 ? 8.01433   3.99362   3.70641   1.000 21.59148 ? 228 MET F HG2    1 
ATOM   2039 H HG3    . MET C 3 64 ? 6.93383   4.90447   2.97958   1.000 21.59148 ? 228 MET F HG3    1 
ATOM   2040 H HE1    . MET C 3 64 ? 10.62524  6.08713   4.94303   1.000 27.00463 ? 228 MET F HE1    1 
ATOM   2041 H HE2    . MET C 3 64 ? 9.39061   5.56886   5.79778   1.000 27.00463 ? 228 MET F HE2    1 
ATOM   2042 H HE3    . MET C 3 64 ? 10.04978  4.62619   4.70216   1.000 27.00463 ? 228 MET F HE3    1 
ATOM   2043 N N      . ALA C 3 65 ? 6.99904   2.02979   6.52772   1.000 17.90870 ? 229 ALA F N      1 
ATOM   2044 C CA     . ALA C 3 65 ? 7.72302   0.79285   6.80814   1.000 19.62506 ? 229 ALA F CA     1 
ATOM   2045 C C      . ALA C 3 65 ? 6.83925   -0.43479  6.62133   1.000 19.64683 ? 229 ALA F C      1 
ATOM   2046 O O      . ALA C 3 65 ? 7.33499   -1.50061  6.24025   1.000 21.68741 ? 229 ALA F O      1 
ATOM   2047 C CB     . ALA C 3 65 ? 8.31437   0.82613   8.22415   1.000 20.92122 ? 229 ALA F CB     1 
ATOM   2048 H H      . ALA C 3 65 ? 6.90039   2.54503   7.20918   1.000 21.49045 ? 229 ALA F H      1 
ATOM   2049 H HA     . ALA C 3 65 ? 8.46260   0.72149   6.18457   1.000 23.55007 ? 229 ALA F HA     1 
ATOM   2050 H HB1    . ALA C 3 65 ? 8.77342   -0.01124  8.39443   1.000 25.10546 ? 229 ALA F HB1    1 
ATOM   2051 H HB2    . ALA C 3 65 ? 8.93956   1.56502   8.28801   1.000 25.10546 ? 229 ALA F HB2    1 
ATOM   2052 H HB3    . ALA C 3 65 ? 7.59514   0.94514   8.86403   1.000 25.10546 ? 229 ALA F HB3    1 
ATOM   2053 N N      . ARG C 3 66 ? 5.53387   -0.31091  6.86118   1.000 20.07200 ? 230 ARG F N      1 
ATOM   2054 C CA     . ARG C 3 66 ? 4.64960   -1.43441  6.56863   1.000 20.70000 ? 230 ARG F CA     1 
ATOM   2055 C C      . ARG C 3 66 ? 4.64804   -1.72822  5.08211   1.000 19.85192 ? 230 ARG F C      1 
ATOM   2056 O O      . ARG C 3 66 ? 4.71782   -2.89482  4.66882   1.000 22.93724 ? 230 ARG F O      1 
ATOM   2057 C CB     . ARG C 3 66 ? 3.23222   -1.16870  7.05909   1.000 22.73956 ? 230 ARG F CB     1 
ATOM   2058 C CG     . ARG C 3 66 ? 2.23625   -2.25709  6.58582   1.000 27.42357 ? 230 ARG F CG     1 
ATOM   2059 C CD     . ARG C 3 66 ? 1.45485   -2.84106  7.70857   1.000 23.84150 ? 230 ARG F CD     1 
ATOM   2060 N NE     . ARG C 3 66 ? 0.79932   -4.11656  7.43133   1.000 19.85738 ? 230 ARG F NE     1 
ATOM   2061 C CZ     . ARG C 3 66 ? -0.21396  -4.61230  8.15240   1.000 23.73975 ? 230 ARG F CZ     1 
ATOM   2062 N NH1    . ARG C 3 66 ? -0.93565  -3.84963  8.97652   1.000 20.21443 ? 230 ARG F NH1    1 
ATOM   2063 N NH2    . ARG C 3 66 ? -0.51535  -5.90649  8.04765   1.000 25.66065 ? 230 ARG F NH2    1 
ATOM   2064 H H      . ARG C 3 66 ? 5.14920   0.38834   7.18162   1.000 24.08640 ? 230 ARG F H      1 
ATOM   2065 H HA     . ARG C 3 66 ? 4.97240   -2.21297  7.04877   1.000 24.84000 ? 230 ARG F HA     1 
ATOM   2066 H HB2    . ARG C 3 66 ? 3.22856   -1.15593  8.02899   1.000 27.28747 ? 230 ARG F HB2    1 
ATOM   2067 H HB3    . ARG C 3 66 ? 2.93185   -0.31301  6.71489   1.000 27.28747 ? 230 ARG F HB3    1 
ATOM   2068 H HG2    . ARG C 3 66 ? 1.61103   -1.86350  5.95726   1.000 32.90828 ? 230 ARG F HG2    1 
ATOM   2069 H HG3    . ARG C 3 66 ? 2.72958   -2.97434  6.15796   1.000 32.90828 ? 230 ARG F HG3    1 
ATOM   2070 H HD2    . ARG C 3 66 ? 2.05630   -2.98436  8.45598   1.000 28.60979 ? 230 ARG F HD2    1 
ATOM   2071 H HD3    . ARG C 3 66 ? 0.76114   -2.21031  7.95718   1.000 28.60979 ? 230 ARG F HD3    1 
ATOM   2072 H HE     . ARG C 3 66 ? 1.08199   -4.57807  6.76297   1.000 23.82886 ? 230 ARG F HE     1 
ATOM   2073 H HH11   . ARG C 3 66 ? -0.75512  -3.01260  9.05644   1.000 24.25732 ? 230 ARG F HH11   1 
ATOM   2074 H HH12   . ARG C 3 66 ? -1.58115  -4.19528  9.42757   1.000 24.25732 ? 230 ARG F HH12   1 
ATOM   2075 H HH21   . ARG C 3 66 ? -0.06088  -6.41262  7.52145   1.000 30.79278 ? 230 ARG F HH21   1 
ATOM   2076 H HH22   . ARG C 3 66 ? -1.16429  -6.23536  8.50627   1.000 30.79278 ? 230 ARG F HH22   1 
ATOM   2077 N N      . ALA C 3 67 ? 4.56843   -0.68074  4.25857   1.000 19.25491 ? 231 ALA F N      1 
ATOM   2078 C CA     . ALA C 3 67 ? 4.69373   -0.89158  2.82509   1.000 19.36386 ? 231 ALA F CA     1 
ATOM   2079 C C      . ALA C 3 67 ? 6.02321   -1.56380  2.48604   1.000 19.09849 ? 231 ALA F C      1 
ATOM   2080 O O      . ALA C 3 67 ? 6.07938   -2.45689  1.63003   1.000 22.03314 ? 231 ALA F O      1 
ATOM   2081 C CB     . ALA C 3 67 ? 4.52374   0.43155   2.08280   1.000 19.26894 ? 231 ALA F CB     1 
ATOM   2082 H H      . ALA C 3 67 ? 4.44602   0.13531   4.50080   1.000 23.10589 ? 231 ALA F H      1 
ATOM   2083 H HA     . ALA C 3 67 ? 3.98470   -1.48066  2.52317   1.000 23.23664 ? 231 ALA F HA     1 
ATOM   2084 H HB1    . ALA C 3 67 ? 4.58382   0.26829   1.12853   1.000 23.12273 ? 231 ALA F HB1    1 
ATOM   2085 H HB2    . ALA C 3 67 ? 3.65594   0.80642   2.30026   1.000 23.12273 ? 231 ALA F HB2    1 
ATOM   2086 H HB3    . ALA C 3 67 ? 5.22597   1.04107   2.35896   1.000 23.12273 ? 231 ALA F HB3    1 
ATOM   2087 N N      . LEU C 3 68 ? 7.10620   -1.16263  3.15237   1.000 19.09418 ? 232 LEU F N      1 
ATOM   2088 C CA     . LEU C 3 68 ? 8.40092   -1.78462  2.86831   1.000 19.57152 ? 232 LEU F CA     1 
ATOM   2089 C C      . LEU C 3 68 ? 8.39000   -3.27802  3.19656   1.000 20.67015 ? 232 LEU F C      1 
ATOM   2090 O O      . LEU C 3 68 ? 8.95080   -4.08641  2.44601   1.000 23.12507 ? 232 LEU F O      1 
ATOM   2091 C CB     . LEU C 3 68 ? 9.53410   -1.08071  3.61825   1.000 19.56660 ? 232 LEU F CB     1 
ATOM   2092 C CG     . LEU C 3 68 ? 9.89129   0.32435   3.13749   1.000 19.90954 ? 232 LEU F CG     1 
ATOM   2093 C CD1    . LEU C 3 68 ? 11.04032  0.90327   3.96396   1.000 21.48403 ? 232 LEU F CD1    1 
ATOM   2094 C CD2    . LEU C 3 68 ? 10.24986  0.32342   1.65302   1.000 21.45791 ? 232 LEU F CD2    1 
ATOM   2095 H H      . LEU C 3 68 ? 7.11962   -0.55047  3.75626   1.000 22.91302 ? 232 LEU F H      1 
ATOM   2096 H HA     . LEU C 3 68 ? 8.57492   -1.68129  1.91966   1.000 23.48582 ? 232 LEU F HA     1 
ATOM   2097 H HB2    . LEU C 3 68 ? 9.27848   -1.00764  4.55111   1.000 23.47991 ? 232 LEU F HB2    1 
ATOM   2098 H HB3    . LEU C 3 68 ? 10.33363  -1.62358  3.53489   1.000 23.47991 ? 232 LEU F HB3    1 
ATOM   2099 H HG     . LEU C 3 68 ? 9.11551   0.89465   3.25502   1.000 23.89145 ? 232 LEU F HG     1 
ATOM   2100 H HD11   . LEU C 3 68 ? 11.24939  1.79164   3.63534   1.000 25.78084 ? 232 LEU F HD11   1 
ATOM   2101 H HD12   . LEU C 3 68 ? 10.76818  0.95011   4.89382   1.000 25.78084 ? 232 LEU F HD12   1 
ATOM   2102 H HD13   . LEU C 3 68 ? 11.81526  0.32672   3.87475   1.000 25.78084 ? 232 LEU F HD13   1 
ATOM   2103 H HD21   . LEU C 3 68 ? 10.61506  1.19017   1.41581   1.000 25.74950 ? 232 LEU F HD21   1 
ATOM   2104 H HD22   . LEU C 3 68 ? 10.90826  -0.36944  1.48760   1.000 25.74950 ? 232 LEU F HD22   1 
ATOM   2105 H HD23   . LEU C 3 68 ? 9.44872   0.14894   1.13473   1.000 25.74950 ? 232 LEU F HD23   1 
ATOM   2106 N N      . ARG C 3 69 ? 7.75221   -3.66652  4.30591   1.000 22.65251 ? 233 ARG F N      1 
ATOM   2107 C CA     . ARG C 3 69 ? 7.68033   -5.08443  4.65489   1.000 24.14348 ? 233 ARG F CA     1 
ATOM   2108 C C      . ARG C 3 69 ? 7.02289   -5.91276  3.55250   1.000 23.38189 ? 233 ARG F C      1 
ATOM   2109 O O      . ARG C 3 69 ? 7.37998   -7.08008  3.34839   1.000 25.36277 ? 233 ARG F O      1 
ATOM   2110 C CB     . ARG C 3 69 ? 6.93113   -5.26578  5.97719   1.000 25.92755 ? 233 ARG F CB     1 
ATOM   2111 C CG     . ARG C 3 69 ? 7.73220   -4.87118  7.21309   1.000 27.91417 ? 233 ARG F CG     1 
ATOM   2112 C CD     . ARG C 3 69 ? 7.15103   -5.45926  8.49606   1.000 29.14499 ? 233 ARG F CD     1 
ATOM   2113 N NE     . ARG C 3 69 ? 5.87949   -4.85068  8.86045   1.000 30.26856 ? 233 ARG F NE     1 
ATOM   2114 C CZ     . ARG C 3 69 ? 5.74650   -3.63523  9.37680   1.000 29.74176 ? 233 ARG F CZ     1 
ATOM   2115 N NH1    . ARG C 3 69 ? 6.79628   -2.85563  9.60638   1.000 28.65487 ? 233 ARG F NH1    1 
ATOM   2116 N NH2    . ARG C 3 69 ? 4.53250   -3.19257  9.67980   1.000 31.65588 ? 233 ARG F NH2    1 
ATOM   2117 H H      . ARG C 3 69 ? 7.36124   -3.13880  4.86112   1.000 27.18301 ? 233 ARG F H      1 
ATOM   2118 H HA     . ARG C 3 69 ? 8.58391   -5.41657  4.77376   1.000 28.97218 ? 233 ARG F HA     1 
ATOM   2119 H HB2    . ARG C 3 69 ? 6.13177   -4.71664  5.95779   1.000 31.11306 ? 233 ARG F HB2    1 
ATOM   2120 H HB3    . ARG C 3 69 ? 6.68931   -6.20054  6.07019   1.000 31.11306 ? 233 ARG F HB3    1 
ATOM   2121 H HG2    . ARG C 3 69 ? 8.64179   -5.19472  7.11884   1.000 33.49701 ? 233 ARG F HG2    1 
ATOM   2122 H HG3    . ARG C 3 69 ? 7.73087   -3.90486  7.29744   1.000 33.49701 ? 233 ARG F HG3    1 
ATOM   2123 H HD2    . ARG C 3 69 ? 7.00504   -6.41012  8.37175   1.000 34.97399 ? 233 ARG F HD2    1 
ATOM   2124 H HD3    . ARG C 3 69 ? 7.77496   -5.31178  9.22397   1.000 34.97399 ? 233 ARG F HD3    1 
ATOM   2125 H HE     . ARG C 3 69 ? 5.16451   -5.31103  8.73212   1.000 36.32227 ? 233 ARG F HE     1 
ATOM   2126 H HH11   . ARG C 3 69 ? 7.58807   -3.13460  9.41972   1.000 34.38584 ? 233 ARG F HH11   1 
ATOM   2127 H HH12   . ARG C 3 69 ? 6.68451   -2.07165  9.94176   1.000 34.38584 ? 233 ARG F HH12   1 
ATOM   2128 H HH21   . ARG C 3 69 ? 3.84585   -3.69141  9.54098   1.000 37.98706 ? 233 ARG F HH21   1 
ATOM   2129 H HH22   . ARG C 3 69 ? 4.43252   -2.40690  10.01495  1.000 37.98706 ? 233 ARG F HH22   1 
ATOM   2130 N N      . ASN C 3 70 ? 6.08940   -5.32647  2.81176   1.000 22.26253 ? 234 ASN F N      1 
ATOM   2131 C CA     . ASN C 3 70 ? 5.39890   -6.07339  1.76389   1.000 23.05838 ? 234 ASN F CA     1 
ATOM   2132 C C      . ASN C 3 70 ? 6.29798   -6.41305  0.58360   1.000 24.74913 ? 234 ASN F C      1 
ATOM   2133 O O      . ASN C 3 70 ? 5.97090   -7.31675  -0.19570  1.000 27.49553 ? 234 ASN F O      1 
ATOM   2134 C CB     . ASN C 3 70 ? 4.18886   -5.27846  1.29252   1.000 22.97871 ? 234 ASN F CB     1 
ATOM   2135 C CG     . ASN C 3 70 ? 3.09535   -5.24905  2.32130   1.000 23.56326 ? 234 ASN F CG     1 
ATOM   2136 O OD1    . ASN C 3 70 ? 3.05488   -6.08260  3.23098   1.000 25.47279 ? 234 ASN F OD1    1 
ATOM   2137 N ND2    . ASN C 3 70 ? 2.19453   -4.30868  2.18415   1.000 23.34319 ? 234 ASN F ND2    1 
ATOM   2138 H H      . ASN C 3 70 ? 5.83900   -4.50777  2.89315   1.000 26.71504 ? 234 ASN F H      1 
ATOM   2139 H HA     . ASN C 3 70 ? 5.08951   -6.91545  2.13282   1.000 27.67006 ? 234 ASN F HA     1 
ATOM   2140 H HB2    . ASN C 3 70 ? 4.45893   -4.36451  1.11182   1.000 27.57446 ? 234 ASN F HB2    1 
ATOM   2141 H HB3    . ASN C 3 70 ? 3.83488   -5.68537  0.48628   1.000 27.57446 ? 234 ASN F HB3    1 
ATOM   2142 H HD21   . ASN C 3 70 ? 2.25038   -3.75165  1.53131   1.000 28.01183 ? 234 ASN F HD21   1 
ATOM   2143 H HD22   . ASN C 3 70 ? 1.54705   -4.24809  2.74691   1.000 28.01183 ? 234 ASN F HD22   1 
ATOM   2144 N N      . TYR C 3 71 ? 7.40556   -5.70302  0.42269   1.000 21.55206 ? 235 TYR F N      1 
ATOM   2145 C CA     . TYR C 3 71 ? 8.36561   -6.02275  -0.62570  1.000 22.49991 ? 235 TYR F CA     1 
ATOM   2146 C C      . TYR C 3 71 ? 9.21416   -7.24774  -0.30556  1.000 27.08579 ? 235 TYR F C      1 
ATOM   2147 O O      . TYR C 3 71 ? 9.94819   -7.71663  -1.18348  1.000 27.32428 ? 235 TYR F O      1 
ATOM   2148 C CB     . TYR C 3 71 ? 9.30771   -4.84664  -0.81471  1.000 22.39944 ? 235 TYR F CB     1 
ATOM   2149 C CG     . TYR C 3 71 ? 8.75289   -3.60573  -1.48965  1.000 20.42532 ? 235 TYR F CG     1 
ATOM   2150 C CD1    . TYR C 3 71 ? 7.98274   -3.67389  -2.64126  1.000 22.01809 ? 235 TYR F CD1    1 
ATOM   2151 C CD2    . TYR C 3 71 ? 9.08328   -2.35301  -1.01285  1.000 19.54481 ? 235 TYR F CD2    1 
ATOM   2152 C CE1    . TYR C 3 71 ? 7.52948   -2.50538  -3.27428  1.000 20.99664 ? 235 TYR F CE1    1 
ATOM   2153 C CE2    . TYR C 3 71 ? 8.66167   -1.21113  -1.62661  1.000 18.53267 ? 235 TYR F CE2    1 
ATOM   2154 C CZ     . TYR C 3 71 ? 7.87558   -1.27599  -2.75502  1.000 19.15784 ? 235 TYR F CZ     1 
ATOM   2155 O OH     . TYR C 3 71 ? 7.49139   -0.09208  -3.33650  1.000 18.96430 ? 235 TYR F OH     1 
ATOM   2156 H H      . TYR C 3 71 ? 7.62600   -5.02865  0.90874   1.000 25.86247 ? 235 TYR F H      1 
ATOM   2157 H HA     . TYR C 3 71 ? 7.87766   -6.19014  -1.44716  1.000 26.99989 ? 235 TYR F HA     1 
ATOM   2158 H HB2    . TYR C 3 71 ? 9.62046   -4.57251  0.06162   1.000 26.87932 ? 235 TYR F HB2    1 
ATOM   2159 H HB3    . TYR C 3 71 ? 10.05518  -5.14829  -1.35433  1.000 26.87932 ? 235 TYR F HB3    1 
ATOM   2160 H HD1    . TYR C 3 71 ? 7.76381   -4.50409  -2.99866  1.000 26.42171 ? 235 TYR F HD1    1 
ATOM   2161 H HD2    . TYR C 3 71 ? 9.60984   -2.28602  -0.24920  1.000 23.45377 ? 235 TYR F HD2    1 
ATOM   2162 H HE1    . TYR C 3 71 ? 7.00042   -2.56024  -4.03717  1.000 25.19597 ? 235 TYR F HE1    1 
ATOM   2163 H HE2    . TYR C 3 71 ? 8.90655   -0.38321  -1.28095  1.000 22.23921 ? 235 TYR F HE2    1 
ATOM   2164 H HH     . TYR C 3 71 ? 7.04899   -0.24486  -4.03403  1.000 22.75715 ? 235 TYR F HH     1 
ATOM   2165 N N      . GLY C 3 72 ? 9.16058   -7.75891  0.92336   1.000 30.27508 ? 236 GLY F N      1 
ATOM   2166 C CA     . GLY C 3 72 ? 10.03715  -8.85951  1.28812   1.000 33.53815 ? 236 GLY F CA     1 
ATOM   2167 C C      . GLY C 3 72 ? 9.80444   -10.10283 0.45211   1.000 37.51595 ? 236 GLY F C      1 
ATOM   2168 O O      . GLY C 3 72 ? 10.75353  -10.80971 0.10336   1.000 40.82888 ? 236 GLY F O      1 
ATOM   2169 H H      . GLY C 3 72 ? 8.63582   -7.49049  1.54959   1.000 36.33010 ? 236 GLY F H      1 
ATOM   2170 H HA2    . GLY C 3 72 ? 10.95994  -8.58412  1.17178   1.000 40.24578 ? 236 GLY F HA2    1 
ATOM   2171 H HA3    . GLY C 3 72 ? 9.89089   -9.08838  2.21931   1.000 40.24578 ? 236 GLY F HA3    1 
ATOM   2172 N N      . LYS C 3 73 ? 8.53990   -10.38736 0.12038   1.000 39.74049 ? 237 LYS F N      1 
ATOM   2173 C CA     . LYS C 3 73 ? 8.21057   -11.60109 -0.61901  0.954 42.50827 ? 237 LYS F CA     1 
ATOM   2174 C C      . LYS C 3 73 ? 8.55456   -11.48809 -2.09966  1.000 42.18537 ? 237 LYS F C      1 
ATOM   2175 O O      . LYS C 3 73 ? 8.90302   -12.49484 -2.72515  0.699 45.26967 ? 237 LYS F O      1 
ATOM   2176 C CB     . LYS C 3 73 ? 6.72742   -11.93996 -0.44077  0.455 45.52414 ? 237 LYS F CB     1 
ATOM   2177 C CG     . LYS C 3 73 ? 6.36108   -13.34322 -0.89985  0.596 48.28694 ? 237 LYS F CG     1 
ATOM   2178 C CD     . LYS C 3 73 ? 5.24059   -13.94549 -0.05487  0.427 49.53057 ? 237 LYS F CD     1 
ATOM   2179 C CE     . LYS C 3 73 ? 5.04499   -15.42723 -0.36008  0.650 50.39664 ? 237 LYS F CE     1 
ATOM   2180 N NZ     . LYS C 3 73 ? 4.98823   -15.68389 -1.82576  0.725 51.33848 ? 237 LYS F NZ     1 
ATOM   2181 H H      . LYS C 3 73 ? 7.86137   -9.89494  0.31200   1.000 47.68858 ? 237 LYS F H      1 
ATOM   2182 H HA     . LYS C 3 73 ? 8.72856   -12.33575 -0.25448  0.997 51.00992 ? 237 LYS F HA     1 
ATOM   2183 H HB2    . LYS C 3 73 ? 6.50170   -11.86750 0.49982   1.000 54.62897 ? 237 LYS F HB2    1 
ATOM   2184 H HB3    . LYS C 3 73 ? 6.19952   -11.31169 -0.95798  1.000 54.62897 ? 237 LYS F HB3    1 
ATOM   2185 H HG2    . LYS C 3 73 ? 6.06099   -13.30983 -1.82166  1.000 57.94433 ? 237 LYS F HG2    1 
ATOM   2186 H HG3    . LYS C 3 73 ? 7.13926   -13.91743 -0.82487  1.000 57.94433 ? 237 LYS F HG3    1 
ATOM   2187 H HD2    . LYS C 3 73 ? 5.46253   -13.85452 0.88500   1.000 59.43668 ? 237 LYS F HD2    1 
ATOM   2188 H HD3    . LYS C 3 73 ? 4.40982   -13.48263 -0.24589  1.000 59.43668 ? 237 LYS F HD3    1 
ATOM   2189 H HE2    . LYS C 3 73 ? 5.78737   -15.93109 0.00858   1.000 60.47597 ? 237 LYS F HE2    1 
ATOM   2190 H HE3    . LYS C 3 73 ? 4.21141   -15.72832 0.03411   1.000 60.47597 ? 237 LYS F HE3    1 
ATOM   2191 H HZ1    . LYS C 3 73 ? 5.78525   -15.53363 -2.19220  1.000 61.60618 ? 237 LYS F HZ1    1 
ATOM   2192 H HZ2    . LYS C 3 73 ? 4.75509   -16.52922 -1.97796  1.000 61.60618 ? 237 LYS F HZ2    1 
ATOM   2193 H HZ3    . LYS C 3 73 ? 4.38953   -15.14621 -2.20598  1.000 61.60618 ? 237 LYS F HZ3    1 
ATOM   2194 N N      . THR C 3 74 ? 8.46346   -10.28909 -2.67600  1.000 38.00277 ? 238 THR F N      1 
ATOM   2195 C CA     . THR C 3 74 ? 8.83198   -10.08928 -4.07196  1.000 36.84965 ? 238 THR F CA     1 
ATOM   2196 C C      . THR C 3 74 ? 10.28399  -9.66365  -4.24520  1.000 35.73300 ? 238 THR F C      1 
ATOM   2197 O O      . THR C 3 74 ? 10.84761  -9.85717  -5.33024  1.000 38.09459 ? 238 THR F O      1 
ATOM   2198 C CB     . THR C 3 74 ? 7.89065   -9.07297  -4.72571  1.000 37.01695 ? 238 THR F CB     1 
ATOM   2199 O OG1    . THR C 3 74 ? 7.74075   -7.93928  -3.86933  1.000 36.91207 ? 238 THR F OG1    1 
ATOM   2200 C CG2    . THR C 3 74 ? 6.51979   -9.70134  -4.97543  1.000 39.01796 ? 238 THR F CG2    1 
ATOM   2201 H H      . THR C 3 74 ? 8.19082   -9.57730  -2.27772  1.000 45.60332 ? 238 THR F H      1 
ATOM   2202 H HA     . THR C 3 74 ? 8.72271   -10.92365 -4.55444  1.000 44.21957 ? 238 THR F HA     1 
ATOM   2203 H HB     . THR C 3 74 ? 8.25962   -8.78887  -5.57662  1.000 44.42034 ? 238 THR F HB     1 
ATOM   2204 H HG1    . THR C 3 74 ? 7.25005   -7.36479  -4.23644  1.000 44.29448 ? 238 THR F HG1    1 
ATOM   2205 H HG21   . THR C 3 74 ? 5.92396   -9.04922  -5.37620  1.000 46.82156 ? 238 THR F HG21   1 
ATOM   2206 H HG22   . THR C 3 74 ? 6.60635   -10.45895 -5.57496  1.000 46.82156 ? 238 THR F HG22   1 
ATOM   2207 H HG23   . THR C 3 74 ? 6.13647   -10.00500 -4.13772  1.000 46.82156 ? 238 THR F HG23   1 
ATOM   2208 N N      . GLY C 3 75 ? 10.89698  -9.08916  -3.21046  1.000 32.97642 ? 239 GLY F N      1 
ATOM   2209 C CA     . GLY C 3 75 ? 12.33425  -8.94104  -3.14662  1.000 31.89511 ? 239 GLY F CA     1 
ATOM   2210 C C      . GLY C 3 75 ? 12.89023  -7.57123  -3.46771  1.000 28.98988 ? 239 GLY F C      1 
ATOM   2211 O O      . GLY C 3 75 ? 14.10973  -7.39649  -3.38437  1.000 29.42850 ? 239 GLY F O      1 
ATOM   2212 H H      . GLY C 3 75 ? 10.48681  -8.77361  -2.52360  1.000 39.57171 ? 239 GLY F H      1 
ATOM   2213 H HA2    . GLY C 3 75 ? 12.62282  -9.16568  -2.24820  1.000 38.27414 ? 239 GLY F HA2    1 
ATOM   2214 H HA3    . GLY C 3 75 ? 12.73186  -9.56708  -3.77183  1.000 38.27414 ? 239 GLY F HA3    1 
ATOM   2215 N N      . GLU C 3 76 ? 12.05158  -6.59080  -3.82400  1.000 26.45701 ? 240 GLU F N      1 
ATOM   2216 C CA     . GLU C 3 76 ? 12.58700  -5.28605  -4.21830  1.000 25.30454 ? 240 GLU F CA     1 
ATOM   2217 C C      . GLU C 3 76 ? 13.38018  -4.63967  -3.09374  1.000 22.62154 ? 240 GLU F C      1 
ATOM   2218 O O      . GLU C 3 76 ? 14.39364  -3.97183  -3.33851  1.000 22.93476 ? 240 GLU F O      1 
ATOM   2219 C CB     . GLU C 3 76 ? 11.45242  -4.35244  -4.62703  1.000 24.63746 ? 240 GLU F CB     1 
ATOM   2220 C CG     . GLU C 3 76 ? 10.75851  -4.71846  -5.93038  1.000 26.01775 ? 240 GLU F CG     1 
ATOM   2221 C CD     . GLU C 3 76 ? 9.55815   -5.64010  -5.74545  1.000 30.01780 ? 240 GLU F CD     1 
ATOM   2222 O OE1    . GLU C 3 76 ? 9.42773   -6.27622  -4.67971  1.000 28.50449 ? 240 GLU F OE1    1 
ATOM   2223 O OE2    . GLU C 3 76 ? 8.73105   -5.72331  -6.67697  1.000 33.54809 ? 240 GLU F OE2    1 
ATOM   2224 H H      . GLU C 3 76 ? 11.19418  -6.65429  -3.84501  1.000 31.74842 ? 240 GLU F H      1 
ATOM   2225 H HA     . GLU C 3 76 ? 13.17564  -5.42380  -4.97687  1.000 30.36544 ? 240 GLU F HA     1 
ATOM   2226 H HB2    . GLU C 3 76 ? 10.78066  -4.36065  -3.92733  1.000 29.56495 ? 240 GLU F HB2    1 
ATOM   2227 H HB3    . GLU C 3 76 ? 11.81286  -3.45785  -4.73041  1.000 29.56495 ? 240 GLU F HB3    1 
ATOM   2228 H HG2    . GLU C 3 76 ? 10.44499  -3.90559  -6.35681  1.000 31.22130 ? 240 GLU F HG2    1 
ATOM   2229 H HG3    . GLU C 3 76 ? 11.39391  -5.17152  -6.50651  1.000 31.22130 ? 240 GLU F HG3    1 
ATOM   2230 N N      . VAL C 3 77 ? 12.89528  -4.77532  -1.86761  1.000 21.76015 ? 241 VAL F N      1 
ATOM   2231 C CA     . VAL C 3 77 ? 13.55800  -4.26406  -0.68009  1.000 21.48066 ? 241 VAL F CA     1 
ATOM   2232 C C      . VAL C 3 77 ? 13.42378  -5.32222  0.39309   1.000 23.49438 ? 241 VAL F C      1 
ATOM   2233 O O      . VAL C 3 77 ? 12.33782  -5.88588  0.58614   1.000 24.03430 ? 241 VAL F O      1 
ATOM   2234 C CB     . VAL C 3 77 ? 12.92268  -2.94846  -0.18337  1.000 20.61036 ? 241 VAL F CB     1 
ATOM   2235 C CG1    . VAL C 3 77 ? 13.71372  -2.38543  1.00446   1.000 22.59618 ? 241 VAL F CG1    1 
ATOM   2236 C CG2    . VAL C 3 77 ? 12.84125  -1.93423  -1.30121  1.000 21.90709 ? 241 VAL F CG2    1 
ATOM   2237 H H      . VAL C 3 77 ? 12.15463  -5.17573  -1.69235  1.000 26.11218 ? 241 VAL F H      1 
ATOM   2238 H HA     . VAL C 3 77 ? 14.49284  -4.09783  -0.87843  1.000 25.77679 ? 241 VAL F HA     1 
ATOM   2239 H HB     . VAL C 3 77 ? 12.01856  -3.13375  0.11520   1.000 24.73243 ? 241 VAL F HB     1 
ATOM   2240 H HG11   . VAL C 3 77 ? 13.35608  -1.51445  1.23767   1.000 27.11541 ? 241 VAL F HG11   1 
ATOM   2241 H HG12   . VAL C 3 77 ? 13.62691  -2.99101  1.75721   1.000 27.11541 ? 241 VAL F HG12   1 
ATOM   2242 H HG13   . VAL C 3 77 ? 14.64668  -2.30313  0.75202   1.000 27.11541 ? 241 VAL F HG13   1 
ATOM   2243 H HG21   . VAL C 3 77 ? 12.50008  -1.09882  -0.94542  1.000 26.28851 ? 241 VAL F HG21   1 
ATOM   2244 H HG22   . VAL C 3 77 ? 13.72810  -1.79899  -1.67014  1.000 26.28851 ? 241 VAL F HG22   1 
ATOM   2245 H HG23   . VAL C 3 77 ? 12.24455  -2.26919  -1.98870  1.000 26.28851 ? 241 VAL F HG23   1 
ATOM   2246 N N      . LYS C 3 78 ? 14.52554  -5.57896  1.09689   1.000 22.83438 ? 242 LYS F N      1 
ATOM   2247 C CA     . LYS C 3 78 ? 14.55303  -6.51313  2.21365   1.000 23.21913 ? 242 LYS F CA     1 
ATOM   2248 C C      . LYS C 3 78 ? 15.06363  -5.80860  3.45734   1.000 20.96821 ? 242 LYS F C      1 
ATOM   2249 O O      . LYS C 3 78 ? 15.93268  -4.93260  3.38158   1.000 21.39874 ? 242 LYS F O      1 
ATOM   2250 C CB     . LYS C 3 78 ? 15.41498  -7.73129  1.90551   1.000 29.58467 ? 242 LYS F CB     1 
ATOM   2251 C CG     . LYS C 3 78 ? 14.76761  -8.66449  0.88866   1.000 37.93026 ? 242 LYS F CG     1 
ATOM   2252 C CD     . LYS C 3 78 ? 15.58046  -9.92969  0.69373   1.000 45.62322 ? 242 LYS F CD     1 
ATOM   2253 C CE     . LYS C 3 78 ? 14.85936  -10.92484 -0.20913  1.000 51.29241 ? 242 LYS F CE     1 
ATOM   2254 N NZ     . LYS C 3 78 ? 15.60768  -12.20652 -0.35557  1.000 55.17169 ? 242 LYS F NZ     1 
ATOM   2255 H H      . LYS C 3 78 ? 15.28774  -5.21296  0.93971   1.000 27.40126 ? 242 LYS F H      1 
ATOM   2256 H HA     . LYS C 3 78 ? 13.65268  -6.82699  2.39187   1.000 27.86295 ? 242 LYS F HA     1 
ATOM   2257 H HB2    . LYS C 3 78 ? 16.26449  -7.43429  1.54354   1.000 35.50160 ? 242 LYS F HB2    1 
ATOM   2258 H HB3    . LYS C 3 78 ? 15.55975  -8.23153  2.72387   1.000 35.50160 ? 242 LYS F HB3    1 
ATOM   2259 H HG2    . LYS C 3 78 ? 13.88412  -8.91553  1.20065   1.000 45.51631 ? 242 LYS F HG2    1 
ATOM   2260 H HG3    . LYS C 3 78 ? 14.70110  -8.21088  0.03385   1.000 45.51631 ? 242 LYS F HG3    1 
ATOM   2261 H HD2    . LYS C 3 78 ? 16.43000  -9.70549  0.28274   1.000 54.74786 ? 242 LYS F HD2    1 
ATOM   2262 H HD3    . LYS C 3 78 ? 15.72937  -10.35155 1.55441   1.000 54.74786 ? 242 LYS F HD3    1 
ATOM   2263 H HE2    . LYS C 3 78 ? 13.98965  -11.12569 0.17055   1.000 61.55089 ? 242 LYS F HE2    1 
ATOM   2264 H HE3    . LYS C 3 78 ? 14.75432  -10.53508 -1.09115  1.000 61.55089 ? 242 LYS F HE3    1 
ATOM   2265 H HZ1    . LYS C 3 78 ? 15.14810  -12.77046 -0.86827  1.000 66.20602 ? 242 LYS F HZ1    1 
ATOM   2266 H HZ2    . LYS C 3 78 ? 16.40020  -12.05508 -0.73117  1.000 66.20602 ? 242 LYS F HZ2    1 
ATOM   2267 H HZ3    . LYS C 3 78 ? 15.73295  -12.57882 0.44305   1.000 66.20602 ? 242 LYS F HZ3    1 
ATOM   2268 N N      . LYS C 3 79 ? 14.48396  -6.17513  4.59326   1.000 22.87067 ? 243 LYS F N      1 
ATOM   2269 C CA     . LYS C 3 79 ? 14.94741  -5.66638  5.86974   1.000 21.39390 ? 243 LYS F CA     1 
ATOM   2270 C C      . LYS C 3 79 ? 16.27045  -6.33549  6.23560   1.000 22.52562 ? 243 LYS F C      1 
ATOM   2271 O O      . LYS C 3 79 ? 16.41375  -7.55875  6.13281   1.000 26.09133 ? 243 LYS F O      1 
ATOM   2272 C CB     . LYS C 3 79 ? 13.89280  -5.93556  6.94622   1.000 22.76275 ? 243 LYS F CB     1 
ATOM   2273 C CG     . LYS C 3 79 ? 14.21362  -5.33178  8.32516   1.000 23.39926 ? 243 LYS F CG     1 
ATOM   2274 C CD     . LYS C 3 79 ? 14.04904  -3.82424  8.34616   1.000 23.00124 ? 243 LYS F CD     1 
ATOM   2275 C CE     . LYS C 3 79 ? 14.36484  -3.21684  9.69651   1.000 23.77423 ? 243 LYS F CE     1 
ATOM   2276 N NZ     . LYS C 3 79 ? 15.79681  -3.43575  10.05639  1.000 25.03346 ? 243 LYS F NZ     1 
ATOM   2277 H H      . LYS C 3 79 ? 13.81955  -6.71827  4.64944   1.000 27.44481 ? 243 LYS F H      1 
ATOM   2278 H HA     . LYS C 3 79 ? 15.09063  -4.70836  5.81872   1.000 25.67268 ? 243 LYS F HA     1 
ATOM   2279 H HB2    . LYS C 3 79 ? 13.04867  -5.55929  6.65168   1.000 27.31530 ? 243 LYS F HB2    1 
ATOM   2280 H HB3    . LYS C 3 79 ? 13.80660  -6.89498  7.06019   1.000 27.31530 ? 243 LYS F HB3    1 
ATOM   2281 H HG2    . LYS C 3 79 ? 13.61230  -5.70984  8.98575   1.000 28.07911 ? 243 LYS F HG2    1 
ATOM   2282 H HG3    . LYS C 3 79 ? 15.13275  -5.53788  8.55671   1.000 28.07911 ? 243 LYS F HG3    1 
ATOM   2283 H HD2    . LYS C 3 79 ? 14.64986  -3.43155  7.69370   1.000 27.60149 ? 243 LYS F HD2    1 
ATOM   2284 H HD3    . LYS C 3 79 ? 13.13043  -3.60345  8.12636   1.000 27.60149 ? 243 LYS F HD3    1 
ATOM   2285 H HE2    . LYS C 3 79 ? 14.19707  -2.26185  9.66889   1.000 28.52907 ? 243 LYS F HE2    1 
ATOM   2286 H HE3    . LYS C 3 79 ? 13.81007  -3.63163  10.37554  1.000 28.52907 ? 243 LYS F HE3    1 
ATOM   2287 H HZ1    . LYS C 3 79 ? 16.32483  -3.07316  9.43847   1.000 30.04016 ? 243 LYS F HZ1    1 
ATOM   2288 H HZ2    . LYS C 3 79 ? 15.97361  -3.06038  10.84375  1.000 30.04016 ? 243 LYS F HZ2    1 
ATOM   2289 H HZ3    . LYS C 3 79 ? 15.96807  -4.30764  10.10712  1.000 30.04016 ? 243 LYS F HZ3    1 
ATOM   2290 N N      . VAL C 3 80 ? 17.23604  -5.52745  6.65122   1.000 22.00346 ? 244 VAL F N      1 
ATOM   2291 C CA     . VAL C 3 80 ? 18.51628  -5.98441  7.17549   1.000 24.40928 ? 244 VAL F CA     1 
ATOM   2292 C C      . VAL C 3 80 ? 18.43002  -5.98943  8.69412   1.000 24.18451 ? 244 VAL F C      1 
ATOM   2293 O O      . VAL C 3 80 ? 17.73786  -5.15887  9.29296   1.000 24.32165 ? 244 VAL F O      1 
ATOM   2294 C CB     . VAL C 3 80 ? 19.62671  -5.03047  6.68007   1.000 26.36123 ? 244 VAL F CB     1 
ATOM   2295 C CG1    . VAL C 3 80 ? 20.96729  -5.32263  7.35682   1.000 28.28338 ? 244 VAL F CG1    1 
ATOM   2296 C CG2    . VAL C 3 80 ? 19.74849  -5.10860  5.15658   1.000 29.55381 ? 244 VAL F CG2    1 
ATOM   2297 H H      . VAL C 3 80 ? 17.17089  -4.67001  6.63916   1.000 26.40415 ? 244 VAL F H      1 
ATOM   2298 H HA     . VAL C 3 80 ? 18.71309  -6.88892  6.88560   1.000 29.29113 ? 244 VAL F HA     1 
ATOM   2299 H HB     . VAL C 3 80 ? 19.38256  -4.12343  6.92209   1.000 31.63348 ? 244 VAL F HB     1 
ATOM   2300 H HG11   . VAL C 3 80 ? 21.67345  -4.87469  6.86530   1.000 33.94005 ? 244 VAL F HG11   1 
ATOM   2301 H HG12   . VAL C 3 80 ? 20.93899  -4.99354  8.26885   1.000 33.94005 ? 244 VAL F HG12   1 
ATOM   2302 H HG13   . VAL C 3 80 ? 21.11962  -6.28060  7.35541   1.000 33.94005 ? 244 VAL F HG13   1 
ATOM   2303 H HG21   . VAL C 3 80 ? 20.47100  -4.52958  4.86742   1.000 35.46457 ? 244 VAL F HG21   1 
ATOM   2304 H HG22   . VAL C 3 80 ? 19.93691  -6.02527  4.90143   1.000 35.46457 ? 244 VAL F HG22   1 
ATOM   2305 H HG23   . VAL C 3 80 ? 18.91295  -4.81931  4.75774   1.000 35.46457 ? 244 VAL F HG23   1 
ATOM   2306 N N      . LYS C 3 81 ? 19.15462  -6.91293  9.32923   1.000 29.40527 ? 245 LYS F N      1 
ATOM   2307 C CA     . LYS C 3 81 ? 19.09536  -7.06305  10.78152  1.000 32.19684 ? 245 LYS F CA     1 
ATOM   2308 C C      . LYS C 3 81 ? 19.96183  -6.03133  11.49352  1.000 31.83798 ? 245 LYS F C      1 
ATOM   2309 O O      . LYS C 3 81 ? 20.75564  -6.36616  12.38076  1.000 34.21489 ? 245 LYS F O      1 
ATOM   2310 C CB     . LYS C 3 81 ? 19.53113  -8.47045  11.19543  1.000 37.22774 ? 245 LYS F CB     1 
ATOM   2311 C CG     . LYS C 3 81 ? 18.61413  -9.58230  10.70923  1.000 45.15630 ? 245 LYS F CG     1 
ATOM   2312 C CD     . LYS C 3 81 ? 17.27348  -9.54518  11.42377  1.000 50.16675 ? 245 LYS F CD     1 
ATOM   2313 C CE     . LYS C 3 81 ? 16.49324  -10.82940 11.20083  1.000 54.08821 ? 245 LYS F CE     1 
ATOM   2314 N NZ     . LYS C 3 81 ? 15.19518  -10.83916 11.93745  1.000 55.40819 ? 245 LYS F NZ     1 
ATOM   2315 H H      . LYS C 3 81 ? 19.68797  -7.46421  8.94036   1.000 35.28632 ? 245 LYS F H      1 
ATOM   2316 H HA     . LYS C 3 81 ? 18.17613  -6.92396  11.05823  1.000 38.63621 ? 245 LYS F HA     1 
ATOM   2317 H HB2    . LYS C 3 81 ? 20.41472  -8.63959  10.83271  1.000 44.67329 ? 245 LYS F HB2    1 
ATOM   2318 H HB3    . LYS C 3 81 ? 19.55629  -8.51382  12.16414  1.000 44.67329 ? 245 LYS F HB3    1 
ATOM   2319 H HG2    . LYS C 3 81 ? 18.45643  -9.47669  9.75798   1.000 54.18756 ? 245 LYS F HG2    1 
ATOM   2320 H HG3    . LYS C 3 81 ? 19.02948  -10.44142 10.88329  1.000 54.18756 ? 245 LYS F HG3    1 
ATOM   2321 H HD2    . LYS C 3 81 ? 17.41934  -9.43768  12.37669  1.000 60.20010 ? 245 LYS F HD2    1 
ATOM   2322 H HD3    . LYS C 3 81 ? 16.74739  -8.80486  11.08308  1.000 60.20010 ? 245 LYS F HD3    1 
ATOM   2323 H HE2    . LYS C 3 81 ? 16.30367  -10.92608 10.25446  1.000 64.90585 ? 245 LYS F HE2    1 
ATOM   2324 H HE3    . LYS C 3 81 ? 17.02205  -11.58080 11.51171  1.000 64.90585 ? 245 LYS F HE3    1 
ATOM   2325 H HZ1    . LYS C 3 81 ? 15.34047  -10.75410 12.81138  1.000 66.48982 ? 245 LYS F HZ1    1 
ATOM   2326 H HZ2    . LYS C 3 81 ? 14.68413  -10.16434 11.66259  1.000 66.48982 ? 245 LYS F HZ2    1 
ATOM   2327 H HZ3    . LYS C 3 81 ? 14.76673  -11.60500 11.78907  1.000 66.48982 ? 245 LYS F HZ3    1 
ATOM   2328 N N      . LYS C 3 82 ? 19.79626  -4.77790  11.10513  1.000 30.73500 ? 246 LYS F N      1 
ATOM   2329 C CA     . LYS C 3 82 ? 20.46461  -3.62920  11.68126  1.000 31.62180 ? 246 LYS F CA     1 
ATOM   2330 C C      . LYS C 3 82 ? 19.42481  -2.52687  11.78229  1.000 28.50788 ? 246 LYS F C      1 
ATOM   2331 O O      . LYS C 3 82 ? 18.49225  -2.46798  10.98072  1.000 26.72530 ? 246 LYS F O      1 
ATOM   2332 C CB     . LYS C 3 82 ? 21.59843  -3.14122  10.77622  1.000 36.05170 ? 246 LYS F CB     1 
ATOM   2333 C CG     . LYS C 3 82 ? 22.71283  -4.15982  10.56063  1.000 40.67178 ? 246 LYS F CG     1 
ATOM   2334 C CD     . LYS C 3 82 ? 23.66498  -4.20585  11.73534  1.000 47.00490 ? 246 LYS F CD     1 
ATOM   2335 C CE     . LYS C 3 82 ? 24.71493  -5.28420  11.53241  1.000 52.04141 ? 246 LYS F CE     1 
ATOM   2336 N NZ     . LYS C 3 82 ? 25.95137  -5.02991  12.32407  1.000 55.49857 ? 246 LYS F NZ     1 
ATOM   2337 H H      . LYS C 3 82 ? 19.26585  -4.55351  10.46645  1.000 36.88200 ? 246 LYS F H      1 
ATOM   2338 H HA     . LYS C 3 82 ? 20.83099  -3.84107  12.55406  1.000 37.94616 ? 246 LYS F HA     1 
ATOM   2339 H HB2    . LYS C 3 82 ? 21.22819  -2.92250  9.90675   1.000 43.26204 ? 246 LYS F HB2    1 
ATOM   2340 H HB3    . LYS C 3 82 ? 21.99552  -2.35161  11.17588  1.000 43.26204 ? 246 LYS F HB3    1 
ATOM   2341 H HG2    . LYS C 3 82 ? 22.32395  -5.04155  10.45002  1.000 48.80613 ? 246 LYS F HG2    1 
ATOM   2342 H HG3    . LYS C 3 82 ? 23.21860  -3.91859  9.76886   1.000 48.80613 ? 246 LYS F HG3    1 
ATOM   2343 H HD2    . LYS C 3 82 ? 24.11423  -3.35059  11.82258  1.000 56.40588 ? 246 LYS F HD2    1 
ATOM   2344 H HD3    . LYS C 3 82 ? 23.17086  -4.40525  12.54589  1.000 56.40588 ? 246 LYS F HD3    1 
ATOM   2345 H HE2    . LYS C 3 82 ? 24.35006  -6.13898  11.81010  1.000 62.44969 ? 246 LYS F HE2    1 
ATOM   2346 H HE3    . LYS C 3 82 ? 24.95943  -5.31685  10.59429  1.000 62.44969 ? 246 LYS F HE3    1 
ATOM   2347 H HZ1    . LYS C 3 82 ? 26.51993  -5.70767  12.22671  1.000 66.59829 ? 246 LYS F HZ1    1 
ATOM   2348 H HZ2    . LYS C 3 82 ? 26.34345  -4.28153  12.04424  1.000 66.59829 ? 246 LYS F HZ2    1 
ATOM   2349 H HZ3    . LYS C 3 82 ? 25.74851  -4.94468  13.18644  1.000 66.59829 ? 246 LYS F HZ3    1 
ATOM   2350 N N      . LYS C 3 83 ? 19.58545  -1.65511  12.76688  1.000 28.92452 ? 247 LYS F N      1 
ATOM   2351 C CA     . LYS C 3 83 ? 18.54256  -0.68422  13.06847  1.000 27.75850 ? 247 LYS F CA     1 
ATOM   2352 C C      . LYS C 3 83 ? 18.21627  0.18967   11.85689  1.000 25.29112 ? 247 LYS F C      1 
ATOM   2353 O O      . LYS C 3 83 ? 19.09279  0.82700   11.27616  1.000 24.62014 ? 247 LYS F O      1 
ATOM   2354 C CB     . LYS C 3 83 ? 18.99257  0.17925   14.24577  1.000 31.33100 ? 247 LYS F CB     1 
ATOM   2355 C CG     . LYS C 3 83 ? 17.87013  0.94835   14.90190  0.660 32.57339 ? 247 LYS F CG     1 
ATOM   2356 C CD     . LYS C 3 83 ? 18.30978  1.58607   16.22677  0.558 34.58357 ? 247 LYS F CD     1 
ATOM   2357 C CE     . LYS C 3 83 ? 18.43831  0.56111   17.35116  0.337 36.78067 ? 247 LYS F CE     1 
ATOM   2358 N NZ     . LYS C 3 83 ? 17.12475  0.05613   17.83957  0.261 37.84279 ? 247 LYS F NZ     1 
ATOM   2359 H H      . LYS C 3 83 ? 20.28059  -1.60413  13.27065  0.384 34.70943 ? 247 LYS F H      1 
ATOM   2360 H HA     . LYS C 3 83 ? 17.72732  -1.15265  13.30690  1.000 33.31019 ? 247 LYS F HA     1 
ATOM   2361 H HB2    . LYS C 3 83 ? 19.39103  -0.39458  14.91871  1.000 37.59720 ? 247 LYS F HB2    1 
ATOM   2362 H HB3    . LYS C 3 83 ? 19.64610  0.82216   13.92882  0.602 37.59720 ? 247 LYS F HB3    1 
ATOM   2363 H HG2    . LYS C 3 83 ? 17.57758  1.65655   14.30713  1.000 39.08806 ? 247 LYS F HG2    1 
ATOM   2364 H HG3    . LYS C 3 83 ? 17.13377  0.34438   15.08601  1.000 39.08806 ? 247 LYS F HG3    1 
ATOM   2365 H HD2    . LYS C 3 83 ? 19.17414  2.00898   16.10462  1.000 41.50028 ? 247 LYS F HD2    1 
ATOM   2366 H HD3    . LYS C 3 83 ? 17.65219  2.24667   16.49525  1.000 41.50028 ? 247 LYS F HD3    1 
ATOM   2367 H HE2    . LYS C 3 83 ? 18.94748  -0.19844  17.02754  1.000 44.13681 ? 247 LYS F HE2    1 
ATOM   2368 H HE3    . LYS C 3 83 ? 18.89637  0.97248   18.10074  0.959 44.13681 ? 247 LYS F HE3    1 
ATOM   2369 H HZ1    . LYS C 3 83 ? 17.25075  -0.57672  18.45253  1.000 45.41135 ? 247 LYS F HZ1    1 
ATOM   2370 H HZ2    . LYS C 3 83 ? 16.65885  0.72165   18.20306  1.000 45.41135 ? 247 LYS F HZ2    1 
ATOM   2371 H HZ3    . LYS C 3 83 ? 16.65938  -0.28612  17.16251  0.828 45.41135 ? 247 LYS F HZ3    1 
ATOM   2372 N N      . LEU C 3 84 ? 16.93369  0.22980   11.48958  1.000 22.99930 ? 248 LEU F N      1 
ATOM   2373 C CA     . LEU C 3 84 ? 16.42883  1.13649   10.44918  1.000 20.90486 ? 248 LEU F CA     1 
ATOM   2374 C C      . LEU C 3 84 ? 17.09851  0.92251   9.09192   1.000 18.80225 ? 248 LEU F C      1 
ATOM   2375 O O      . LEU C 3 84 ? 17.09221  1.81443   8.24076   1.000 18.27219 ? 248 LEU F O      1 
ATOM   2376 C CB     . LEU C 3 84 ? 16.53227  2.60194   10.88376  1.000 22.06385 ? 248 LEU F CB     1 
ATOM   2377 C CG     . LEU C 3 84 ? 15.65099  2.98608   12.08127  1.000 20.63313 ? 248 LEU F CG     1 
ATOM   2378 C CD1    . LEU C 3 84 ? 16.03028  4.35544   12.62323  1.000 22.38209 ? 248 LEU F CD1    1 
ATOM   2379 C CD2    . LEU C 3 84 ? 14.19476  3.01759   11.68848  1.000 22.38007 ? 248 LEU F CD2    1 
ATOM   2380 H H      . LEU C 3 84 ? 16.32238  -0.26758  11.83385  1.000 27.59915 ? 248 LEU F H      1 
ATOM   2381 H HA     . LEU C 3 84 ? 15.48997  0.92920   10.32088  1.000 25.08584 ? 248 LEU F HA     1 
ATOM   2382 H HB2    . LEU C 3 84 ? 17.45290  2.78484   11.12850  1.000 26.47662 ? 248 LEU F HB2    1 
ATOM   2383 H HB3    . LEU C 3 84 ? 16.26994  3.16243   10.13681  1.000 26.47662 ? 248 LEU F HB3    1 
ATOM   2384 H HG     . LEU C 3 84 ? 15.78692  2.31858   12.77183  1.000 24.75976 ? 248 LEU F HG     1 
ATOM   2385 H HD11   . LEU C 3 84 ? 15.46551  4.56129   13.38451  1.000 26.85851 ? 248 LEU F HD11   1 
ATOM   2386 H HD12   . LEU C 3 84 ? 16.96093  4.34032   12.89628  1.000 26.85851 ? 248 LEU F HD12   1 
ATOM   2387 H HD13   . LEU C 3 84 ? 15.90069  5.01779   11.92652  1.000 26.85851 ? 248 LEU F HD13   1 
ATOM   2388 H HD21   . LEU C 3 84 ? 13.66001  3.21318   12.47377  1.000 26.85609 ? 248 LEU F HD21   1 
ATOM   2389 H HD22   . LEU C 3 84 ? 14.06319  3.70675   11.01866  1.000 26.85609 ? 248 LEU F HD22   1 
ATOM   2390 H HD23   . LEU C 3 84 ? 13.94657  2.15264   11.32632  1.000 26.85609 ? 248 LEU F HD23   1 
ATOM   2391 N N      . THR C 3 85 ? 17.59708  -0.28166  8.84402   1.000 19.23066 ? 249 THR F N      1 
ATOM   2392 C CA     . THR C 3 85 ? 18.41005  -0.58311  7.67237   1.000 18.41119 ? 249 THR F CA     1 
ATOM   2393 C C      . THR C 3 85 ? 17.72245  -1.59274  6.75882   1.000 18.00052 ? 249 THR F C      1 
ATOM   2394 O O      . THR C 3 85 ? 17.10211  -2.55723  7.22472   1.000 18.82998 ? 249 THR F O      1 
ATOM   2395 C CB     . THR C 3 85 ? 19.76606  -1.11249  8.12411   1.000 20.47219 ? 249 THR F CB     1 
ATOM   2396 O OG1    . THR C 3 85 ? 20.34412  -0.15245  9.01953   1.000 21.51285 ? 249 THR F OG1    1 
ATOM   2397 C CG2    . THR C 3 85 ? 20.69670  -1.33851  6.94515   1.000 20.90053 ? 249 THR F CG2    1 
ATOM   2398 H H      . THR C 3 85 ? 17.47446  -0.96184  9.35581   1.000 23.07679 ? 249 THR F H      1 
ATOM   2399 H HA     . THR C 3 85 ? 18.52979  0.21955   7.14106   1.000 22.09343 ? 249 THR F HA     1 
ATOM   2400 H HB     . THR C 3 85 ? 19.65616  -1.96850  8.56692   1.000 24.56663 ? 249 THR F HB     1 
ATOM   2401 H HG1    . THR C 3 85 ? 21.05217  -0.45914  9.35150   1.000 25.81542 ? 249 THR F HG1    1 
ATOM   2402 H HG21   . THR C 3 85 ? 21.57265  -1.61001  7.26123   1.000 25.08063 ? 249 THR F HG21   1 
ATOM   2403 H HG22   . THR C 3 85 ? 20.34040  -2.03332  6.36967   1.000 25.08063 ? 249 THR F HG22   1 
ATOM   2404 H HG23   . THR C 3 85 ? 20.78687  -0.52028  6.43204   1.000 25.08063 ? 249 THR F HG23   1 
ATOM   2405 N N      . TYR C 3 86 ? 17.82643  -1.33772  5.45283   1.000 17.89434 ? 250 TYR F N      1 
ATOM   2406 C CA     . TYR C 3 86 ? 17.12712  -2.08013  4.40862   1.000 17.66530 ? 250 TYR F CA     1 
ATOM   2407 C C      . TYR C 3 86 ? 18.09980  -2.29153  3.24938   1.000 18.30004 ? 250 TYR F C      1 
ATOM   2408 O O      . TYR C 3 86 ? 19.17910  -1.70668  3.21646   1.000 19.19955 ? 250 TYR F O      1 
ATOM   2409 C CB     . TYR C 3 86 ? 15.90843  -1.29454  3.91459   1.000 18.11196 ? 250 TYR F CB     1 
ATOM   2410 C CG     . TYR C 3 86 ? 14.79046  -1.19204  4.92440   1.000 18.50711 ? 250 TYR F CG     1 
ATOM   2411 C CD1    . TYR C 3 86 ? 14.79298  -0.21041  5.90121   1.000 19.01863 ? 250 TYR F CD1    1 
ATOM   2412 C CD2    . TYR C 3 86 ? 13.73644  -2.08983  4.90965   1.000 19.59112 ? 250 TYR F CD2    1 
ATOM   2413 C CE1    . TYR C 3 86 ? 13.77507  -0.11710  6.83115   1.000 20.81947 ? 250 TYR F CE1    1 
ATOM   2414 C CE2    . TYR C 3 86 ? 12.72038  -2.01754  5.83355   1.000 20.09549 ? 250 TYR F CE2    1 
ATOM   2415 C CZ     . TYR C 3 86 ? 12.73429  -1.02110  6.79238   1.000 20.52964 ? 250 TYR F CZ     1 
ATOM   2416 O OH     . TYR C 3 86 ? 11.70149  -0.96818  7.71055   1.000 22.93629 ? 250 TYR F OH     1 
ATOM   2417 H H      . TYR C 3 86 ? 18.31975  -0.70955  5.13403   1.000 21.47321 ? 250 TYR F H      1 
ATOM   2418 H HA     . TYR C 3 86 ? 16.83694  -2.94125  4.74800   1.000 21.19836 ? 250 TYR F HA     1 
ATOM   2419 H HB2    . TYR C 3 86 ? 16.18910  -0.39282  3.69318   1.000 21.73435 ? 250 TYR F HB2    1 
ATOM   2420 H HB3    . TYR C 3 86 ? 15.55396  -1.73467  3.12621   1.000 21.73435 ? 250 TYR F HB3    1 
ATOM   2421 H HD1    . TYR C 3 86 ? 15.49475  0.39907   5.93201   1.000 22.82235 ? 250 TYR F HD1    1 
ATOM   2422 H HD2    . TYR C 3 86 ? 13.71517  -2.75600  4.26106   1.000 23.50935 ? 250 TYR F HD2    1 
ATOM   2423 H HE1    . TYR C 3 86 ? 13.79175  0.55046   7.47844   1.000 24.98337 ? 250 TYR F HE1    1 
ATOM   2424 H HE2    . TYR C 3 86 ? 12.02649  -2.63643  5.81361   1.000 24.11459 ? 250 TYR F HE2    1 
ATOM   2425 H HH     . TYR C 3 86 ? 11.28521  -1.69775  7.71707   1.000 27.52355 ? 250 TYR F HH     1 
ATOM   2426 N N      . GLN C 3 87 ? 17.69698  -3.10429  2.26836   1.000 19.12973 ? 251 GLN F N      1 
ATOM   2427 C CA     . GLN C 3 87 ? 18.55789  -3.42097  1.13003   1.000 18.97191 ? 251 GLN F CA     1 
ATOM   2428 C C      . GLN C 3 87 ? 17.72810  -3.57177  -0.13794  1.000 19.16667 ? 251 GLN F C      1 
ATOM   2429 O O      . GLN C 3 87 ? 16.81407  -4.39339  -0.18511  1.000 21.92859 ? 251 GLN F O      1 
ATOM   2430 C CB     . GLN C 3 87 ? 19.34813  -4.71010  1.39562   1.000 21.24197 ? 251 GLN F CB     1 
ATOM   2431 C CG     . GLN C 3 87 ? 20.32686  -5.08744  0.30464   1.000 23.21890 ? 251 GLN F CG     1 
ATOM   2432 C CD     . GLN C 3 87 ? 21.25207  -6.23074  0.71730   1.000 27.49379 ? 251 GLN F CD     1 
ATOM   2433 O OE1    . GLN C 3 87 ? 20.94420  -7.00499  1.62601   1.000 31.48944 ? 251 GLN F OE1    1 
ATOM   2434 N NE2    . GLN C 3 87 ? 22.38782  -6.33217  0.05448   1.000 27.12098 ? 251 GLN F NE2    1 
ATOM   2435 H H      . GLN C 3 87 ? 16.92623  -3.48482  2.24149   1.000 22.95567 ? 251 GLN F H      1 
ATOM   2436 H HA     . GLN C 3 87 ? 19.16949  -2.68115  0.99033   1.000 22.76629 ? 251 GLN F HA     1 
ATOM   2437 H HB2    . GLN C 3 87 ? 19.85371  -4.59824  2.21585   1.000 25.49037 ? 251 GLN F HB2    1 
ATOM   2438 H HB3    . GLN C 3 87 ? 18.71966  -5.44283  1.49060   1.000 25.49037 ? 251 GLN F HB3    1 
ATOM   2439 H HG2    . GLN C 3 87 ? 19.83254  -5.36914  -0.48098  1.000 27.86268 ? 251 GLN F HG2    1 
ATOM   2440 H HG3    . GLN C 3 87 ? 20.87683  -4.31722  0.09204   1.000 27.86268 ? 251 GLN F HG3    1 
ATOM   2441 H HE21   . GLN C 3 87 ? 22.57207  -5.77168  -0.57122  1.000 32.54518 ? 251 GLN F HE21   1 
ATOM   2442 H HE22   . GLN C 3 87 ? 22.94413  -6.95880  0.24799   1.000 32.54518 ? 251 GLN F HE22   1 
ATOM   2443 N N      . PHE C 3 88 ? 18.07473  -2.80853  -1.17327  1.000 20.00256 ? 252 PHE F N      1 
ATOM   2444 C CA     . PHE C 3 88 ? 17.45211  -2.96938  -2.48258  1.000 19.90576 ? 252 PHE F CA     1 
ATOM   2445 C C      . PHE C 3 88 ? 17.98224  -4.22259  -3.16866  1.000 21.40528 ? 252 PHE F C      1 
ATOM   2446 O O      . PHE C 3 88 ? 19.14076  -4.61391  -2.98928  1.000 21.45428 ? 252 PHE F O      1 
ATOM   2447 C CB     . PHE C 3 88 ? 17.81374  -1.79805  -3.39930  1.000 19.60275 ? 252 PHE F CB     1 
ATOM   2448 C CG     . PHE C 3 88 ? 17.25054  -0.46457  -2.97750  1.000 19.16963 ? 252 PHE F CG     1 
ATOM   2449 C CD1    . PHE C 3 88 ? 15.88671  -0.21168  -3.03810  1.000 19.64007 ? 252 PHE F CD1    1 
ATOM   2450 C CD2    . PHE C 3 88 ? 18.09649  0.56346   -2.61143  1.000 20.10615 ? 252 PHE F CD2    1 
ATOM   2451 C CE1    . PHE C 3 88 ? 15.37988  1.02121   -2.66617  1.000 18.98399 ? 252 PHE F CE1    1 
ATOM   2452 C CE2    . PHE C 3 88 ? 17.60775  1.80962   -2.24025  1.000 19.56293 ? 252 PHE F CE2    1 
ATOM   2453 C CZ     . PHE C 3 88 ? 16.24058  2.04291   -2.28102  1.000 19.76649 ? 252 PHE F CZ     1 
ATOM   2454 H H      . PHE C 3 88 ? 18.66991  -2.18851  -1.14266  1.000 24.00307 ? 252 PHE F H      1 
ATOM   2455 H HA     . PHE C 3 88 ? 16.49136  -3.01852  -2.35824  1.000 23.88691 ? 252 PHE F HA     1 
ATOM   2456 H HB2    . PHE C 3 88 ? 18.77966  -1.71216  -3.42192  1.000 23.52330 ? 252 PHE F HB2    1 
ATOM   2457 H HB3    . PHE C 3 88 ? 17.47667  -1.98829  -4.28874  1.000 23.52330 ? 252 PHE F HB3    1 
ATOM   2458 H HD1    . PHE C 3 88 ? 15.30777  -0.87768  -3.33167  1.000 23.56809 ? 252 PHE F HD1    1 
ATOM   2459 H HD2    . PHE C 3 88 ? 19.01507  0.41815   -2.61342  1.000 24.12738 ? 252 PHE F HD2    1 
ATOM   2460 H HE1    . PHE C 3 88 ? 14.46136  1.16665   -2.67387  1.000 22.78079 ? 252 PHE F HE1    1 
ATOM   2461 H HE2    . PHE C 3 88 ? 18.19089  2.48067   -1.96723  1.000 23.47552 ? 252 PHE F HE2    1 
ATOM   2462 H HZ     . PHE C 3 88 ? 15.90179  2.87817   -2.05196  1.000 23.71979 ? 252 PHE F HZ     1 
ATOM   2463 N N      . SER C 3 89 ? 17.14769  -4.81869  -4.01600  1.000 24.32596 ? 253 SER F N      1 
ATOM   2464 C CA     . SER C 3 89 ? 17.59100  -5.94594  -4.82667  1.000 26.92525 ? 253 SER F CA     1 
ATOM   2465 C C      . SER C 3 89 ? 18.52222  -5.47750  -5.93630  1.000 27.41806 ? 253 SER F C      1 
ATOM   2466 O O      . SER C 3 89 ? 18.51869  -4.31044  -6.34091  1.000 26.75098 ? 253 SER F O      1 
ATOM   2467 C CB     . SER C 3 89 ? 16.39854  -6.62234  -5.49164  1.000 26.47755 ? 253 SER F CB     1 
ATOM   2468 O OG     . SER C 3 89 ? 15.85697  -5.78774  -6.49422  1.000 27.65955 ? 253 SER F OG     1 
ATOM   2469 H H      . SER C 3 89 ? 16.32745  -4.59113  -4.13853  1.000 29.19115 ? 253 SER F H      1 
ATOM   2470 H HA     . SER C 3 89 ? 18.05299  -6.57550  -4.25124  1.000 32.31029 ? 253 SER F HA     1 
ATOM   2471 H HB2    . SER C 3 89 ? 16.68965  -7.45528  -5.89458  1.000 31.77307 ? 253 SER F HB2    1 
ATOM   2472 H HB3    . SER C 3 89 ? 15.71858  -6.79739  -4.82238  1.000 31.77307 ? 253 SER F HB3    1 
ATOM   2473 H HG     . SER C 3 89 ? 15.16915  -6.14148  -6.82189  1.000 33.19146 ? 253 SER F HG     1 
ATOM   2474 N N      . GLY C 3 90 ? 19.32938  -6.41690  -6.43851  1.000 29.74591 ? 254 GLY F N      1 
ATOM   2475 C CA     . GLY C 3 90 ? 20.14378  -6.12004  -7.60345  1.000 30.83367 ? 254 GLY F CA     1 
ATOM   2476 C C      . GLY C 3 90 ? 19.31707  -5.66653  -8.79044  1.000 31.84473 ? 254 GLY F C      1 
ATOM   2477 O O      . GLY C 3 90 ? 19.73327  -4.79557  -9.55716  1.000 31.29136 ? 254 GLY F O      1 
ATOM   2478 H H      . GLY C 3 90 ? 19.41791  -7.21352  -6.12681  1.000 35.69509 ? 254 GLY F H      1 
ATOM   2479 H HA2    . GLY C 3 90 ? 20.77328  -5.41568  -7.38319  1.000 37.00041 ? 254 GLY F HA2    1 
ATOM   2480 H HA3    . GLY C 3 90 ? 20.63660  -6.91490  -7.86080  1.000 37.00041 ? 254 GLY F HA3    1 
ATOM   2481 N N      . GLU C 3 91 ? 18.12871  -6.24307  -8.95384  1.000 32.76958 ? 255 GLU F N      1 
ATOM   2482 C CA     . GLU C 3 91 ? 17.27385  -5.86649  -10.07209 1.000 35.40216 ? 255 GLU F CA     1 
ATOM   2483 C C      . GLU C 3 91 ? 16.84119  -4.40970  -9.94575  1.000 33.50535 ? 255 GLU F C      1 
ATOM   2484 O O      . GLU C 3 91 ? 16.92021  -3.63621  -10.90651 1.000 32.82238 ? 255 GLU F O      1 
ATOM   2485 C CB     . GLU C 3 91 ? 16.06559  -6.80365  -10.11519 1.000 38.80182 ? 255 GLU F CB     1 
ATOM   2486 C CG     . GLU C 3 91 ? 16.41522  -8.25933  -10.45395 1.000 43.48678 ? 255 GLU F CG     1 
ATOM   2487 C CD     . GLU C 3 91 ? 17.00020  -9.06253  -9.28761  1.000 46.23946 ? 255 GLU F CD     1 
ATOM   2488 O OE1    . GLU C 3 91 ? 17.31921  -8.48251  -8.22530  0.922 45.25982 ? 255 GLU F OE1    1 
ATOM   2489 O OE2    . GLU C 3 91 ? 17.13712  -10.29657 -9.44232  0.467 47.39803 ? 255 GLU F OE2    1 
ATOM   2490 H H      . GLU C 3 91 ? 17.79905  -6.84691  -8.43780  1.000 39.32350 ? 255 GLU F H      1 
ATOM   2491 H HA     . GLU C 3 91 ? 17.75776  -5.95988  -10.90756 1.000 42.48260 ? 255 GLU F HA     1 
ATOM   2492 H HB2    . GLU C 3 91 ? 15.63687  -6.79809  -9.24510  1.000 46.56218 ? 255 GLU F HB2    1 
ATOM   2493 H HB3    . GLU C 3 91 ? 15.44810  -6.48360  -10.79134 1.000 46.56218 ? 255 GLU F HB3    1 
ATOM   2494 H HG2    . GLU C 3 91 ? 15.60767  -8.71161  -10.74413 1.000 52.18414 ? 255 GLU F HG2    1 
ATOM   2495 H HG3    . GLU C 3 91 ? 17.07150  -8.26133  -11.16823 1.000 52.18414 ? 255 GLU F HG3    1 
ATOM   2496 N N      . VAL C 3 92 ? 16.42072  -4.00773  -8.74644  1.000 30.58833 ? 256 VAL F N      1 
ATOM   2497 C CA     . VAL C 3 92 ? 16.03660  -2.61885  -8.52379  1.000 29.11345 ? 256 VAL F CA     1 
ATOM   2498 C C      . VAL C 3 92 ? 17.21609  -1.68751  -8.77338  1.000 30.42303 ? 256 VAL F C      1 
ATOM   2499 O O      . VAL C 3 92 ? 17.05795  -0.61244  -9.36311  1.000 31.42478 ? 256 VAL F O      1 
ATOM   2500 C CB     . VAL C 3 92 ? 15.46154  -2.44908  -7.10444  1.000 30.05902 ? 256 VAL F CB     1 
ATOM   2501 C CG1    . VAL C 3 92 ? 15.52040  -1.00118  -6.68322  1.000 30.25604 ? 256 VAL F CG1    1 
ATOM   2502 C CG2    . VAL C 3 92 ? 14.01792  -2.98099  -7.05193  1.000 30.73154 ? 256 VAL F CG2    1 
ATOM   2503 H H      . VAL C 3 92 ? 16.35006  -4.51383  -8.05472  1.000 36.70599 ? 256 VAL F H      1 
ATOM   2504 H HA     . VAL C 3 92 ? 15.34151  -2.38531  -9.15878  1.000 34.93614 ? 256 VAL F HA     1 
ATOM   2505 H HB     . VAL C 3 92 ? 15.99517  -2.96229  -6.47774  1.000 36.07082 ? 256 VAL F HB     1 
ATOM   2506 H HG11   . VAL C 3 92 ? 14.92628  -0.86753  -5.92821  1.000 36.30725 ? 256 VAL F HG11   1 
ATOM   2507 H HG12   . VAL C 3 92 ? 16.43099  -0.78263  -6.43033  1.000 36.30725 ? 256 VAL F HG12   1 
ATOM   2508 H HG13   . VAL C 3 92 ? 15.24089  -0.44439  -7.42670  1.000 36.30725 ? 256 VAL F HG13   1 
ATOM   2509 H HG21   . VAL C 3 92 ? 13.67379  -2.87208  -6.15159  1.000 36.87784 ? 256 VAL F HG21   1 
ATOM   2510 H HG22   . VAL C 3 92 ? 13.47312  -2.47809  -7.67737  1.000 36.87784 ? 256 VAL F HG22   1 
ATOM   2511 H HG23   . VAL C 3 92 ? 14.01839  -3.92017  -7.29450  1.000 36.87784 ? 256 VAL F HG23   1 
ATOM   2512 N N      . LEU C 3 93 ? 18.41334  -2.07692  -8.31754  1.000 30.54516 ? 257 LEU F N      1 
ATOM   2513 C CA     . LEU C 3 93 ? 19.59215  -1.23094  -8.48128  1.000 31.27765 ? 257 LEU F CA     1 
ATOM   2514 C C      . LEU C 3 93 ? 20.02832  -1.13269  -9.93235  1.000 33.45633 ? 257 LEU F C      1 
ATOM   2515 O O      . LEU C 3 93 ? 20.62179  -0.12137  -10.33365 1.000 34.05518 ? 257 LEU F O      1 
ATOM   2516 C CB     . LEU C 3 93 ? 20.74857  -1.79183  -7.65659  1.000 29.49161 ? 257 LEU F CB     1 
ATOM   2517 C CG     . LEU C 3 93 ? 20.52664  -1.75228  -6.14657  1.000 30.23868 ? 257 LEU F CG     1 
ATOM   2518 C CD1    . LEU C 3 93 ? 21.55652  -2.63503  -5.45905  1.000 31.12373 ? 257 LEU F CD1    1 
ATOM   2519 C CD2    . LEU C 3 93 ? 20.60273  -0.32108  -5.63461  1.000 31.03042 ? 257 LEU F CD2    1 
ATOM   2520 H H      . LEU C 3 93 ? 18.56539  -2.82079  -7.91364  1.000 36.65420 ? 257 LEU F H      1 
ATOM   2521 H HA     . LEU C 3 93 ? 19.37090  -0.34127  -8.16436  1.000 37.53318 ? 257 LEU F HA     1 
ATOM   2522 H HB2    . LEU C 3 93 ? 20.88639  -2.71822  -7.90899  1.000 35.38993 ? 257 LEU F HB2    1 
ATOM   2523 H HB3    . LEU C 3 93 ? 21.54517  -1.27324  -7.85001  1.000 35.38993 ? 257 LEU F HB3    1 
ATOM   2524 H HG     . LEU C 3 93 ? 19.64257  -2.08983  -5.93354  1.000 36.28642 ? 257 LEU F HG     1 
ATOM   2525 H HD11   . LEU C 3 93 ? 21.28815  -2.77434  -4.53738  1.000 37.34847 ? 257 LEU F HD11   1 
ATOM   2526 H HD12   . LEU C 3 93 ? 21.60272  -3.48599  -5.92234  1.000 37.34847 ? 257 LEU F HD12   1 
ATOM   2527 H HD13   . LEU C 3 93 ? 22.42031  -2.19472  -5.48911  1.000 37.34847 ? 257 LEU F HD13   1 
ATOM   2528 H HD21   . LEU C 3 93 ? 20.53418  -0.32773  -4.66706  1.000 37.23650 ? 257 LEU F HD21   1 
ATOM   2529 H HD22   . LEU C 3 93 ? 21.45060  0.06584   -5.90350  1.000 37.23650 ? 257 LEU F HD22   1 
ATOM   2530 H HD23   . LEU C 3 93 ? 19.87077  0.18957   -6.01457  1.000 37.23650 ? 257 LEU F HD23   1 
ATOM   2531 N N      . GLY C 3 94 ? 19.78468  -2.17569  -10.71905 1.000 38.00683 ? 258 GLY F N      1 
ATOM   2532 C CA     . GLY C 3 94 ? 20.23612  -2.19461  -12.09965 1.000 46.61721 ? 258 GLY F CA     1 
ATOM   2533 C C      . GLY C 3 94 ? 19.31937  -1.42856  -13.02865 1.000 56.29751 ? 258 GLY F C      1 
ATOM   2534 O O      . GLY C 3 94 ? 19.77267  -0.83933  -14.01440 1.000 58.40141 ? 258 GLY F O      1 
ATOM   2535 H H      . GLY C 3 94 ? 19.36037  -2.88330  -10.47647 1.000 45.60819 ? 258 GLY F H      1 
ATOM   2536 H HA2    . GLY C 3 94 ? 21.12050  -1.79951  -12.15131 1.000 55.94065 ? 258 GLY F HA2    1 
ATOM   2537 H HA3    . GLY C 3 94 ? 20.28220  -3.11333  -12.40743 1.000 55.94065 ? 258 GLY F HA3    1 
ATOM   2538 N N      . ARG C 3 95 ? 18.02556  -1.43528  -12.72986 1.000 63.01984 ? 259 ARG F N      1 
ATOM   2539 C CA     . ARG C 3 95 ? 17.04561  -0.75124  -13.56467 1.000 70.08086 ? 259 ARG F CA     1 
ATOM   2540 C C      . ARG C 3 95 ? 17.33049  0.74460   -13.60542 1.000 75.70592 ? 259 ARG F C      1 
ATOM   2541 O O      . ARG C 3 95 ? 16.84170  1.50023   -12.76456 1.000 79.15430 ? 259 ARG F O      1 
ATOM   2542 C CB     . ARG C 3 95 ? 15.63182  -0.99947  -13.03662 1.000 70.29015 ? 259 ARG F CB     1 
ATOM   2543 H H      . ARG C 3 95 ? 17.68777  -1.83106  -12.04513 1.000 75.62381 ? 259 ARG F H      1 
ATOM   2544 H HA     . ARG C 3 95 ? 17.09480  -1.09784  -14.46929 1.000 84.09703 ? 259 ARG F HA     1 
HETATM 2545 O O      . HOH D 4 .  ? 9.80627   3.73806   15.29870  1.000 45.34540 ? 101 HOH C O      1 
HETATM 2546 O O      . HOH D 4 .  ? -15.12461 -1.42776  7.74838   1.000 39.72150 ? 102 HOH C O      1 
HETATM 2547 O O      . HOH D 4 .  ? 14.18241  8.68998   21.45878  1.000 53.52325 ? 103 HOH C O      1 
HETATM 2548 O O      . HOH D 4 .  ? 16.48294  -3.04507  14.69773  1.000 35.69354 ? 104 HOH C O      1 
HETATM 2549 O O      . HOH D 4 .  ? 3.99132   0.58857   17.19952  1.000 42.65985 ? 105 HOH C O      1 
HETATM 2550 O O      . HOH D 4 .  ? -13.00677 6.48165   0.02630   1.000 37.69855 ? 106 HOH C O      1 
HETATM 2551 O O      . HOH D 4 .  ? 11.81450  0.28560   10.16108  1.000 30.26239 ? 107 HOH C O      1 
HETATM 2552 O O      . HOH D 4 .  ? 2.97111   -1.17815  10.83130  1.000 28.52593 ? 108 HOH C O      1 
HETATM 2553 O O      . HOH D 4 .  ? 9.65058   -3.16542  9.37413   1.000 27.29210 ? 109 HOH C O      1 
HETATM 2554 O O      . HOH D 4 .  ? -6.11134  -6.22649  0.36040   1.000 39.93768 ? 110 HOH C O      1 
HETATM 2555 O O      . HOH D 4 .  ? 2.128     1.844     30.870    1.000 44.75800 ? 111 HOH C O      1 
HETATM 2556 O O      . HOH D 4 .  ? -17.384   -2.851    4.524     1.000 24.38342 ? 112 HOH C O      1 
HETATM 2557 O O      . HOH D 4 .  ? 7.95141   6.27190   20.20653  1.000 44.21378 ? 113 HOH C O      1 
HETATM 2558 O O      . HOH D 4 .  ? -12.56787 5.21107   4.44821   1.000 29.51021 ? 114 HOH C O      1 
HETATM 2559 O O      . HOH D 4 .  ? -8.98865  -4.72995  -2.22892  1.000 37.66762 ? 115 HOH C O      1 
HETATM 2560 O O      . HOH D 4 .  ? 4.58500   -1.14841  33.69593  1.000 32.05546 ? 116 HOH C O      1 
HETATM 2561 O O      . HOH D 4 .  ? -11.59161 5.00838   -5.78602  1.000 32.97411 ? 117 HOH C O      1 
HETATM 2562 O O      . HOH D 4 .  ? 14.17751  -8.30453  10.42121  1.000 36.12532 ? 118 HOH C O      1 
HETATM 2563 O O      . HOH D 4 .  ? -10.28319 -8.43654  4.26053   1.000 32.12588 ? 119 HOH C O      1 
HETATM 2564 O O      . HOH D 4 .  ? 8.45549   -8.89309  7.15896   1.000 43.37753 ? 120 HOH C O      1 
HETATM 2565 O O      . HOH D 4 .  ? -15.63549 5.83442   2.12975   1.000 27.81102 ? 121 HOH C O      1 
HETATM 2566 O O      . HOH D 4 .  ? -9.17302  -0.61829  6.58251   1.000 29.75192 ? 122 HOH C O      1 
HETATM 2567 O O      . HOH D 4 .  ? 12.59802  -3.91613  17.29238  1.000 33.89566 ? 123 HOH C O      1 
HETATM 2568 O O      . HOH D 4 .  ? -9.40734  -5.61572  1.15428   1.000 34.69506 ? 124 HOH C O      1 
HETATM 2569 O O      . HOH D 4 .  ? 3.10540   -9.48039  14.36305  1.000 41.07462 ? 125 HOH C O      1 
HETATM 2570 O O      . HOH D 4 .  ? -3.74361  9.29116   -11.08676 1.000 52.30758 ? 126 HOH C O      1 
HETATM 2571 O O      . HOH D 4 .  ? -1.00818  -9.04511  13.16819  1.000 53.80289 ? 127 HOH C O      1 
HETATM 2572 O O      . HOH D 4 .  ? -8.94956  -3.91040  9.90358   1.000 35.69125 ? 128 HOH C O      1 
HETATM 2573 O O      . HOH D 4 .  ? 4.11124   4.33467   28.71146  1.000 32.70362 ? 129 HOH C O      1 
HETATM 2574 O O      . HOH D 4 .  ? 8.43917   -2.83594  32.25681  1.000 34.36929 ? 130 HOH C O      1 
HETATM 2575 O O      . HOH D 4 .  ? 6.70143   2.71668   18.14785  1.000 43.93225 ? 131 HOH C O      1 
HETATM 2576 O O      . HOH D 4 .  ? 5.39217   2.47965   22.04177  1.000 45.94246 ? 132 HOH C O      1 
HETATM 2577 O O      . HOH D 4 .  ? 10.34255  -10.18090 9.02563   1.000 51.88781 ? 133 HOH C O      1 
HETATM 2578 O O      . HOH D 4 .  ? 13.72364  -0.00483  19.85104  1.000 37.29902 ? 134 HOH C O      1 
HETATM 2579 O O      . HOH D 4 .  ? 13.95876  3.44091   25.54094  1.000 34.48909 ? 135 HOH C O      1 
HETATM 2580 O O      . HOH D 4 .  ? -3.29302  0.70991   -10.53480 1.000 32.91453 ? 136 HOH C O      1 
HETATM 2581 O O      . HOH D 4 .  ? -7.46501  5.45991   -16.85129 1.000 64.20835 ? 137 HOH C O      1 
HETATM 2582 O O      . HOH D 4 .  ? 3.71545   7.90515   35.25564  1.000 31.56159 ? 138 HOH C O      1 
HETATM 2583 O O      . HOH D 4 .  ? -3.48345  -8.01054  14.16237  1.000 40.36394 ? 139 HOH C O      1 
HETATM 2584 O O      . HOH D 4 .  ? -5.14469  8.52354   -13.51289 1.000 60.17888 ? 140 HOH C O      1 
HETATM 2585 O O      . HOH D 4 .  ? 10.49954  -7.26112  7.09800   1.000 30.95478 ? 141 HOH C O      1 
HETATM 2586 O O      . HOH D 4 .  ? 13.98392  3.13755   22.69247  1.000 47.12631 ? 142 HOH C O      1 
HETATM 2587 O O      . HOH D 4 .  ? -6.06869  3.93468   1.03165   1.000 26.73153 ? 143 HOH C O      1 
HETATM 2588 O O      . HOH D 4 .  ? -3.05988  -1.85121  -12.08860 1.000 34.49759 ? 144 HOH C O      1 
HETATM 2589 O O      . HOH D 4 .  ? -4.03852  -7.25696  2.29084   1.000 39.18970 ? 145 HOH C O      1 
HETATM 2590 O O      . HOH D 4 .  ? 4.76313   0.38563   23.69177  1.000 47.51995 ? 146 HOH C O      1 
HETATM 2591 O O      . HOH D 4 .  ? -7.54492  -9.08103  13.00069  1.000 45.95922 ? 147 HOH C O      1 
HETATM 2592 O O      . HOH D 4 .  ? 9.279     6.040     32.892    1.000 40.29320 ? 148 HOH C O      1 
HETATM 2593 O O      . HOH D 4 .  ? 5.265     0.527     29.768    1.000 40.70598 ? 149 HOH C O      1 
HETATM 2594 O O      . HOH D 4 .  ? 9.33627   -7.32538  15.87658  1.000 43.09114 ? 150 HOH C O      1 
HETATM 2595 O O      . HOH D 4 .  ? 6.04720   6.46179   24.50086  1.000 39.89503 ? 151 HOH C O      1 
HETATM 2596 O O      . HOH D 4 .  ? 0.81292   -10.72989 14.02209  1.000 43.16031 ? 152 HOH C O      1 
HETATM 2597 O O      . HOH D 4 .  ? -9.809    5.248     -10.081   1.000 34.87374 ? 153 HOH C O      1 
HETATM 2598 O O      . HOH D 4 .  ? -8.71454  2.24684   5.83458   1.000 33.67417 ? 154 HOH C O      1 
HETATM 2599 O O      . HOH D 4 .  ? -3.18330  2.83057   -7.57149  1.000 34.57528 ? 155 HOH C O      1 
HETATM 2600 O O      . HOH D 4 .  ? -6.06936  -7.67873  -13.40390 1.000 39.94085 ? 156 HOH C O      1 
HETATM 2601 O O      . HOH D 4 .  ? -5.16066  4.90338   -1.04826  1.000 43.93631 ? 157 HOH C O      1 
HETATM 2602 O O      . HOH D 4 .  ? -15.704   -5.981    7.417     1.000 48.22600 ? 158 HOH C O      1 
HETATM 2603 O O      . HOH D 4 .  ? -6.32593  -10.41895 5.23658   1.000 44.15425 ? 159 HOH C O      1 
HETATM 2604 O O      . HOH D 4 .  ? 5.357     -1.753    31.004    1.000 58.42203 ? 160 HOH C O      1 
HETATM 2605 O O      . HOH D 4 .  ? 9.63159   -0.41502  11.61881  1.000 36.98069 ? 161 HOH C O      1 
HETATM 2606 O O      . HOH D 4 .  ? -2.88249  5.81133   -4.78740  1.000 38.80830 ? 162 HOH C O      1 
HETATM 2607 O O      . HOH D 4 .  ? 3.61655   5.66205   26.11871  1.000 48.19441 ? 163 HOH C O      1 
HETATM 2608 O O      . HOH D 4 .  ? -10.83311 -5.75040  -1.19983  1.000 38.64311 ? 164 HOH C O      1 
HETATM 2609 O O      . HOH D 4 .  ? 7.37242   5.13475   17.81787  1.000 44.59859 ? 165 HOH C O      1 
HETATM 2610 O O      . HOH E 4 .  ? -2.49567  -4.41345  23.14530  1.000 56.13570 ? 101 HOH D O      1 
HETATM 2611 O O      . HOH E 4 .  ? 0.11915   -10.68779 -10.64731 1.000 59.51568 ? 102 HOH D O      1 
HETATM 2612 O O      . HOH E 4 .  ? -10.18252 -8.81170  -12.65890 1.000 19.76706 ? 103 HOH D O      1 
HETATM 2613 O O      . HOH E 4 .  ? 20.13161  -4.29317  26.73921  1.000 42.89094 ? 104 HOH D O      1 
HETATM 2614 O O      . HOH E 4 .  ? 17.74115  -1.69865  21.17924  1.000 41.04644 ? 105 HOH D O      1 
HETATM 2615 O O      . HOH E 4 .  ? 1.41798   0.31557   16.30319  1.000 42.75438 ? 106 HOH D O      1 
HETATM 2616 O O      . HOH E 4 .  ? -7.89532  6.05867   14.38203  1.000 50.95938 ? 107 HOH D O      1 
HETATM 2617 O O      . HOH E 4 .  ? -8.18955  -9.49169  -5.14673  1.000 42.89509 ? 108 HOH D O      1 
HETATM 2618 O O      . HOH E 4 .  ? -3.07799  6.69192   9.42815   1.000 32.76613 ? 109 HOH D O      1 
HETATM 2619 O O      . HOH E 4 .  ? -9.09925  -13.59344 -4.65953  1.000 29.89941 ? 110 HOH D O      1 
HETATM 2620 O O      . HOH E 4 .  ? -15.57708 -1.60953  -11.02669 1.000 29.19805 ? 111 HOH D O      1 
HETATM 2621 O O      . HOH E 4 .  ? 1.49564   -0.41722  20.40242  1.000 52.39129 ? 112 HOH D O      1 
HETATM 2622 O O      . HOH E 4 .  ? -7.49908  -2.89108  13.64911  1.000 49.93024 ? 113 HOH D O      1 
HETATM 2623 O O      . HOH E 4 .  ? 3.34129   -1.60397  22.33850  1.000 35.75745 ? 114 HOH D O      1 
HETATM 2624 O O      . HOH E 4 .  ? 2.84264   3.81719   -4.86566  1.000 21.71315 ? 115 HOH D O      1 
HETATM 2625 O O      . HOH E 4 .  ? -4.90471  -5.65332  -12.27380 1.000 33.08222 ? 116 HOH D O      1 
HETATM 2626 O O      . HOH E 4 .  ? -0.34932  8.97157   3.73043   1.000 20.13299 ? 117 HOH D O      1 
HETATM 2627 O O      . HOH E 4 .  ? -0.28094  -4.77893  3.37808   1.000 27.38117 ? 118 HOH D O      1 
HETATM 2628 O O      . HOH E 4 .  ? -9.47068  6.50055   12.34612  1.000 48.92833 ? 119 HOH D O      1 
HETATM 2629 O O      . HOH E 4 .  ? -5.50417  8.58901   11.66848  1.000 52.24716 ? 120 HOH D O      1 
HETATM 2630 O O      . HOH E 4 .  ? -11.44184 -16.10031 -10.92792 1.000 24.24656 ? 121 HOH D O      1 
HETATM 2631 O O      . HOH E 4 .  ? -2.40266  -6.38438  -2.95678  1.000 33.62652 ? 122 HOH D O      1 
HETATM 2632 O O      . HOH E 4 .  ? 5.36891   -3.70476  25.77850  1.000 38.73090 ? 123 HOH D O      1 
HETATM 2633 O O      . HOH E 4 .  ? -10.10889 5.96235   8.12397   1.000 36.00578 ? 124 HOH D O      1 
HETATM 2634 O O      . HOH E 4 .  ? -7.08939  2.32840   3.53285   1.000 21.07593 ? 125 HOH D O      1 
HETATM 2635 O O      . HOH E 4 .  ? -3.31247  2.89786   -1.95443  1.000 22.96207 ? 126 HOH D O      1 
HETATM 2636 O O      . HOH E 4 .  ? -8.83142  -14.55032 -10.58550 1.000 36.93219 ? 127 HOH D O      1 
HETATM 2637 O O      . HOH E 4 .  ? 3.22594   -9.23036  17.25938  1.000 41.08001 ? 128 HOH D O      1 
HETATM 2638 O O      . HOH E 4 .  ? 5.73738   -12.78958 24.49733  1.000 46.15924 ? 129 HOH D O      1 
HETATM 2639 O O      . HOH E 4 .  ? 2.12375   -7.82898  -9.25100  1.000 52.85160 ? 130 HOH D O      1 
HETATM 2640 O O      . HOH E 4 .  ? 1.54079   2.51495   3.40864   1.000 18.95112 ? 131 HOH D O      1 
HETATM 2641 O O      . HOH E 4 .  ? 5.41626   -5.57520  -9.17305  1.000 41.19280 ? 132 HOH D O      1 
HETATM 2642 O O      . HOH E 4 .  ? -7.28913  -6.09066  -3.96361  1.000 28.73910 ? 133 HOH D O      1 
HETATM 2643 O O      . HOH E 4 .  ? 4.29677   -8.69349  24.34308  1.000 42.78622 ? 134 HOH D O      1 
HETATM 2644 O O      . HOH E 4 .  ? 14.26843  -7.93273  25.85691  1.000 27.83829 ? 135 HOH D O      1 
HETATM 2645 O O      . HOH E 4 .  ? 14.97481  -1.32316  21.72646  1.000 36.98602 ? 136 HOH D O      1 
HETATM 2646 O O      . HOH E 4 .  ? -1.42097  2.01889   -5.58679  1.000 28.08529 ? 137 HOH D O      1 
HETATM 2647 O O      . HOH E 4 .  ? 10.47510  -7.16005  18.32427  1.000 44.96092 ? 138 HOH D O      1 
HETATM 2648 O O      . HOH E 4 .  ? -1.48270  -6.27579  0.94343   1.000 42.09405 ? 139 HOH D O      1 
HETATM 2649 O O      . HOH E 4 .  ? -19.54916 -7.24336  -11.22474 1.000 40.00626 ? 140 HOH D O      1 
HETATM 2650 O O      . HOH E 4 .  ? -3.36523  -7.90002  -4.84190  1.000 38.65942 ? 141 HOH D O      1 
HETATM 2651 O O      . HOH E 4 .  ? -13.31321 -11.90109 -6.25562  1.000 42.45887 ? 142 HOH D O      1 
HETATM 2652 O O      . HOH E 4 .  ? -7.85715  -9.55528  -11.86368 1.000 30.23329 ? 143 HOH D O      1 
HETATM 2653 O O      . HOH E 4 .  ? 9.43473   -9.73164  24.90211  1.000 31.44286 ? 144 HOH D O      1 
HETATM 2654 O O      . HOH E 4 .  ? -4.99295  -6.19309  -2.18536  1.000 31.42925 ? 145 HOH D O      1 
HETATM 2655 O O      . HOH E 4 .  ? -5.563    -12.593   -4.892    1.000 42.67825 ? 146 HOH D O      1 
HETATM 2656 O O      . HOH E 4 .  ? -2.18043  -8.09986  16.80560  1.000 39.89900 ? 147 HOH D O      1 
HETATM 2657 O O      . HOH E 4 .  ? -1.40286  0.41010   -8.55549  1.000 41.32871 ? 148 HOH D O      1 
HETATM 2658 O O      . HOH E 4 .  ? 12.28486  -13.62448 21.89189  1.000 54.28230 ? 149 HOH D O      1 
HETATM 2659 O O      . HOH E 4 .  ? -11.34721 -10.41746 -13.83610 1.000 31.82007 ? 150 HOH D O      1 
HETATM 2660 O O      . HOH E 4 .  ? -0.20356  -9.27007  16.78199  1.000 55.76345 ? 151 HOH D O      1 
HETATM 2661 O O      . HOH E 4 .  ? -3.66380  4.46018   11.94418  1.000 50.68651 ? 152 HOH D O      1 
HETATM 2662 O O      . HOH E 4 .  ? 1.63120   -5.37477  -5.48370  1.000 33.65556 ? 153 HOH D O      1 
HETATM 2663 O O      . HOH E 4 .  ? 0.90624   3.12008   -6.57542  1.000 28.88808 ? 154 HOH D O      1 
HETATM 2664 O O      . HOH E 4 .  ? -3.439    -13.310   -6.369    1.000 37.52713 ? 155 HOH D O      1 
HETATM 2665 O O      . HOH E 4 .  ? -2.860    -13.097   -8.945    1.000 50.96199 ? 156 HOH D O      1 
HETATM 2666 O O      . HOH E 4 .  ? -13.88027 -9.28376  -6.51374  1.000 38.55517 ? 157 HOH D O      1 
HETATM 2667 O O      . HOH E 4 .  ? -0.148    -12.873   -4.442    1.000 51.48144 ? 158 HOH D O      1 
HETATM 2668 O O      . HOH F 4 .  ? 17.91139  1.85620   -11.02182 1.000 37.48497 ? 301 HOH F O      1 
HETATM 2669 O O      . HOH F 4 .  ? -8.60953  4.67594   4.05145   1.000 52.86317 ? 302 HOH F O      1 
HETATM 2670 O O      . HOH F 4 .  ? 16.76706  7.40725   -9.70155  1.000 54.23045 ? 303 HOH F O      1 
HETATM 2671 O O      . HOH F 4 .  ? 27.88786  -6.58098  4.78571   1.000 53.98040 ? 304 HOH F O      1 
HETATM 2672 O O      . HOH F 4 .  ? 4.81890   10.97750  11.30926  1.000 39.46814 ? 305 HOH F O      1 
HETATM 2673 O O      . HOH F 4 .  ? 9.996     17.422    2.277     1.000 66.35043 ? 306 HOH F O      1 
HETATM 2674 O O      . HOH F 4 .  ? -9.28974  7.56305   5.79402   1.000 60.35248 ? 307 HOH F O      1 
HETATM 2675 O O      . HOH F 4 .  ? 9.77297   -2.48713  7.18581   1.000 26.46967 ? 308 HOH F O      1 
HETATM 2676 O O      . HOH F 4 .  ? 18.23053  12.30947  0.19456   1.000 29.09533 ? 309 HOH F O      1 
HETATM 2677 O O      . HOH F 4 .  ? 16.14878  3.50533   -11.25445 1.000 44.21127 ? 310 HOH F O      1 
HETATM 2678 O O      . HOH F 4 .  ? 11.91484  7.90999   -10.94810 1.000 49.54441 ? 311 HOH F O      1 
HETATM 2679 O O      . HOH F 4 .  ? 9.31919   8.18834   14.32594  1.000 45.24828 ? 312 HOH F O      1 
HETATM 2680 O O      . HOH F 4 .  ? 30.366    1.892     -1.928    1.000 30.13877 ? 313 HOH F O      1 
HETATM 2681 O O      . HOH F 4 .  ? 20.08956  11.31852  12.20504  1.000 34.93904 ? 314 HOH F O      1 
HETATM 2682 O O      . HOH F 4 .  ? 28.62666  3.40136   5.61518   1.000 25.17692 ? 315 HOH F O      1 
HETATM 2683 O O      . HOH F 4 .  ? 11.12063  -5.70213  2.95870   1.000 30.55714 ? 316 HOH F O      1 
HETATM 2684 O O      . HOH F 4 .  ? 22.38528  -7.81021  3.73222   1.000 44.64293 ? 317 HOH F O      1 
HETATM 2685 O O      . HOH F 4 .  ? 23.86166  11.51902  4.92839   1.000 40.56370 ? 318 HOH F O      1 
HETATM 2686 O O      . HOH F 4 .  ? -1.49703  9.79665   9.99630   1.000 45.44824 ? 319 HOH F O      1 
HETATM 2687 O O      . HOH F 4 .  ? 30.249    -3.219    -6.483    1.000 36.52708 ? 320 HOH F O      1 
HETATM 2688 O O      . HOH F 4 .  ? 21.52814  -5.85808  -3.37011  1.000 27.50225 ? 321 HOH F O      1 
HETATM 2689 O O      . HOH F 4 .  ? 20.34358  10.71882  0.99264   1.000 31.48860 ? 322 HOH F O      1 
HETATM 2690 O O      . HOH F 4 .  ? 10.81530  13.01606  -4.09807  1.000 36.69816 ? 323 HOH F O      1 
HETATM 2691 O O      . HOH F 4 .  ? 1.67546   -6.19180  5.87883   1.000 45.72939 ? 324 HOH F O      1 
HETATM 2692 O O      . HOH F 4 .  ? 19.67036  5.63377   12.17225  1.000 32.41035 ? 325 HOH F O      1 
HETATM 2693 O O      . HOH F 4 .  ? 5.83446   -0.47555  10.60206  1.000 31.46770 ? 326 HOH F O      1 
HETATM 2694 O O      . HOH F 4 .  ? -1.39177  14.09018  1.16400   1.000 31.29080 ? 327 HOH F O      1 
HETATM 2695 O O      . HOH F 4 .  ? 15.925    15.752    6.833     1.000 40.21101 ? 328 HOH F O      1 
HETATM 2696 O O      . HOH F 4 .  ? 1.13836   5.09657   11.84392  1.000 28.34940 ? 329 HOH F O      1 
HETATM 2697 O O      . HOH F 4 .  ? 32.05613  -3.78193  -4.24457  1.000 43.66421 ? 330 HOH F O      1 
HETATM 2698 O O      . HOH F 4 .  ? 13.40957  -6.81502  -7.32833  1.000 31.57216 ? 331 HOH F O      1 
HETATM 2699 O O      . HOH F 4 .  ? 5.27140   -6.81988  -3.23744  1.000 37.09132 ? 332 HOH F O      1 
HETATM 2700 O O      . HOH F 4 .  ? 23.05235  13.51930  8.57516   1.000 50.25413 ? 333 HOH F O      1 
HETATM 2701 O O      . HOH F 4 .  ? 5.06527   -2.42034  -0.98261  1.000 30.60391 ? 334 HOH F O      1 
HETATM 2702 O O      . HOH F 4 .  ? -6.25260  6.78477   1.76879   1.000 53.80928 ? 335 HOH F O      1 
HETATM 2703 O O      . HOH F 4 .  ? 22.43321  10.00772  -0.62732  1.000 28.09114 ? 336 HOH F O      1 
HETATM 2704 O O      . HOH F 4 .  ? 16.36487  -6.74440  -1.66225  1.000 39.74014 ? 337 HOH F O      1 
HETATM 2705 O O      . HOH F 4 .  ? 14.51873  0.49881   -9.90042  1.000 35.10793 ? 338 HOH F O      1 
HETATM 2706 O O      . HOH F 4 .  ? 8.09558   15.16793  -3.07361  1.000 49.19332 ? 339 HOH F O      1 
HETATM 2707 O O      . HOH F 4 .  ? 20.78889  13.11843  10.28484  1.000 38.14186 ? 340 HOH F O      1 
HETATM 2708 O O      . HOH F 4 .  ? -0.07179  12.52644  2.92063   1.000 28.77346 ? 341 HOH F O      1 
HETATM 2709 O O      . HOH F 4 .  ? 6.19960   15.48720  -1.43663  1.000 39.66677 ? 342 HOH F O      1 
HETATM 2710 O O      . HOH F 4 .  ? 31.69528  -7.27933  2.29611   1.000 33.96582 ? 343 HOH F O      1 
HETATM 2711 O O      . HOH F 4 .  ? 2.37634   2.57889   -9.07041  1.000 35.48878 ? 344 HOH F O      1 
HETATM 2712 O O      . HOH F 4 .  ? 9.37765   -4.41594  -9.13064  1.000 35.58472 ? 345 HOH F O      1 
HETATM 2713 O O      . HOH F 4 .  ? -4.00832  7.07164   -2.02856  1.000 40.84560 ? 346 HOH F O      1 
HETATM 2714 O O      . HOH F 4 .  ? 4.22523   -6.99270  7.94002   1.000 33.58058 ? 347 HOH F O      1 
HETATM 2715 O O      . HOH F 4 .  ? 14.91777  18.51388  1.62805   1.000 43.75361 ? 348 HOH F O      1 
HETATM 2716 O O      . HOH F 4 .  ? 15.20839  -9.48400  7.87470   1.000 48.23481 ? 349 HOH F O      1 
HETATM 2717 O O      . HOH F 4 .  ? 17.76482  -9.14778  4.17221   1.000 39.82150 ? 350 HOH F O      1 
HETATM 2718 O O      . HOH F 4 .  ? 1.15969   0.45526   9.60570   1.000 27.18129 ? 351 HOH F O      1 
HETATM 2719 O O      . HOH F 4 .  ? -1.48878  3.92415   -3.58060  1.000 26.51819 ? 352 HOH F O      1 
HETATM 2720 O O      . HOH F 4 .  ? 15.39045  -5.85252  11.55255  1.000 33.37724 ? 353 HOH F O      1 
HETATM 2721 O O      . HOH F 4 .  ? 18.13991  -4.23652  -13.44208 1.000 48.91881 ? 354 HOH F O      1 
HETATM 2722 O O      . HOH F 4 .  ? 14.79372  14.71652  -4.39118  1.000 53.49317 ? 355 HOH F O      1 
HETATM 2723 O O      . HOH F 4 .  ? 11.51409  11.26447  12.75189  1.000 26.80159 ? 356 HOH F O      1 
HETATM 2724 O O      . HOH F 4 .  ? 17.26045  11.13885  -8.29790  1.000 37.92187 ? 357 HOH F O      1 
HETATM 2725 O O      . HOH F 4 .  ? -4.86565  12.93325  -4.34517  1.000 43.87326 ? 358 HOH F O      1 
HETATM 2726 O O      . HOH F 4 .  ? 22.63123  -4.88469  -9.76288  1.000 36.65185 ? 359 HOH F O      1 
HETATM 2727 O O      . HOH F 4 .  ? -3.88593  12.54915  8.85762   1.000 35.66459 ? 360 HOH F O      1 
HETATM 2728 O O      . HOH F 4 .  ? 24.10333  5.42458   11.59419  1.000 46.51176 ? 361 HOH F O      1 
HETATM 2729 O O      . HOH F 4 .  ? 12.29709  10.81524  -4.68131  1.000 27.45973 ? 362 HOH F O      1 
HETATM 2730 O O      . HOH F 4 .  ? 5.58105   6.14895   12.73189  1.000 29.76546 ? 363 HOH F O      1 
HETATM 2731 O O      . HOH F 4 .  ? 2.15013   12.99232  4.48057   1.000 25.58900 ? 364 HOH F O      1 
HETATM 2732 O O      . HOH F 4 .  ? 2.80174   -2.53624  -0.07272  1.000 27.46161 ? 365 HOH F O      1 
HETATM 2733 O O      . HOH F 4 .  ? 20.71872  -8.96568  7.92747   1.000 35.81337 ? 366 HOH F O      1 
HETATM 2734 O O      . HOH F 4 .  ? 24.02381  8.52956   1.14277   1.000 22.92010 ? 367 HOH F O      1 
HETATM 2735 O O      . HOH F 4 .  ? 7.87554   0.94320   12.12202  1.000 55.52900 ? 368 HOH F O      1 
HETATM 2736 O O      . HOH F 4 .  ? 26.56279  5.26909   6.29921   1.000 35.09108 ? 369 HOH F O      1 
HETATM 2737 O O      . HOH F 4 .  ? 27.51216  -8.80324  3.32996   1.000 53.98699 ? 370 HOH F O      1 
HETATM 2738 O O      . HOH F 4 .  ? 24.89009  2.15877   9.56250   1.000 35.78978 ? 371 HOH F O      1 
HETATM 2739 O O      . HOH F 4 .  ? 10.06286  2.31074   -10.77627 1.000 36.42183 ? 372 HOH F O      1 
HETATM 2740 O O      . HOH F 4 .  ? 11.90331  -7.71276  4.56825   1.000 35.48182 ? 373 HOH F O      1 
HETATM 2741 O O      . HOH F 4 .  ? 18.80720  10.30343  14.49346  1.000 32.93315 ? 374 HOH F O      1 
HETATM 2742 O O      . HOH F 4 .  ? 23.33743  -0.24164  9.41141   1.000 31.42757 ? 375 HOH F O      1 
HETATM 2743 O O      . HOH F 4 .  ? 23.66409  2.44046   12.88249  1.000 42.66754 ? 376 HOH F O      1 
HETATM 2744 O O      . HOH F 4 .  ? 19.54130  -9.05977  -4.95760  1.000 43.17093 ? 377 HOH F O      1 
HETATM 2745 O O      . HOH F 4 .  ? 8.23092   3.86545   -9.89652  1.000 30.82197 ? 378 HOH F O      1 
HETATM 2746 O O      . HOH F 4 .  ? 12.63008  -1.29525  -11.04090 1.000 41.48575 ? 379 HOH F O      1 
HETATM 2747 O O      . HOH F 4 .  ? 3.01342   14.76489  -6.50449  1.000 41.05331 ? 380 HOH F O      1 
HETATM 2748 O O      . HOH F 4 .  ? 22.28906  -1.86565  14.26679  1.000 37.21777 ? 381 HOH F O      1 
HETATM 2749 O O      . HOH F 4 .  ? 17.88134  16.39266  4.98524   1.000 44.37480 ? 382 HOH F O      1 
HETATM 2750 O O      . HOH F 4 .  ? 19.97033  8.03309   13.27201  1.000 38.91662 ? 383 HOH F O      1 
HETATM 2751 O O      . HOH F 4 .  ? 3.83902   10.00598  -8.67400  1.000 41.24033 ? 384 HOH F O      1 
HETATM 2752 O O      . HOH F 4 .  ? 5.73708   3.45392   -11.37106 1.000 42.20807 ? 385 HOH F O      1 
HETATM 2753 O O      . HOH F 4 .  ? 4.48605   8.71684   13.36306  1.000 42.31686 ? 386 HOH F O      1 
HETATM 2754 O O      . HOH F 4 .  ? 14.77205  -2.13389  17.46399  1.000 45.22391 ? 387 HOH F O      1 
HETATM 2755 O O      . HOH F 4 .  ? 4.00922   -4.40605  -3.97598  1.000 37.53113 ? 388 HOH F O      1 
HETATM 2756 O O      . HOH F 4 .  ? 14.52268  12.49301  -5.32735  1.000 34.58550 ? 389 HOH F O      1 
HETATM 2757 O O      . HOH F 4 .  ? -5.93525  8.01326   -0.48499  1.000 39.39270 ? 390 HOH F O      1 
HETATM 2758 O O      . HOH F 4 .  ? 23.371    1.548     -11.617   1.000 46.19088 ? 391 HOH F O      1 
HETATM 2759 O O      . HOH F 4 .  ? 6.64137   16.93848  2.78150   1.000 40.81237 ? 392 HOH F O      1 
HETATM 2760 O O      . HOH F 4 .  ? 22.10164  2.80400   14.40263  1.000 48.51382 ? 393 HOH F O      1 
HETATM 2761 O O      . HOH F 4 .  ? 10.70351  -4.81875  5.94502   1.000 37.32271 ? 394 HOH F O      1 
HETATM 2762 O O      . HOH F 4 .  ? 9.21845   17.78838  -2.62835  1.000 52.16609 ? 395 HOH F O      1 
HETATM 2763 O O      . HOH F 4 .  ? 23.85366  -3.84418  15.00653  1.000 52.43740 ? 396 HOH F O      1 
HETATM 2764 O O      . HOH F 4 .  ? 23.39447  -2.57997  -10.70254 1.000 37.84561 ? 397 HOH F O      1 
HETATM 2765 O O      . HOH F 4 .  ? 20.84057  15.73369  11.12455  1.000 50.72228 ? 398 HOH F O      1 
HETATM 2766 O O      . HOH F 4 .  ? 25.72614  -5.70826  4.12317   1.000 41.61492 ? 399 HOH F O      1 
HETATM 2767 O O      . HOH F 4 .  ? 20.59766  -8.26229  -2.53181  1.000 44.09599 ? 400 HOH F O      1 
HETATM 2768 O O      . HOH F 4 .  ? 11.422    18.489    4.517     1.000 46.10942 ? 401 HOH F O      1 
HETATM 2769 O O      . HOH F 4 .  ? 23.07839  -6.60406  -5.50286  1.000 34.50115 ? 402 HOH F O      1 
HETATM 2770 O O      . HOH F 4 .  ? 19.41842  3.79661   14.12308  1.000 48.67750 ? 403 HOH F O      1 
HETATM 2771 O O      . HOH F 4 .  ? 20.738    21.298    6.323     1.000 48.16592 ? 404 HOH F O      1 
HETATM 2772 O O      . HOH F 4 .  ? 15.42255  17.60006  4.48100   1.000 44.55469 ? 405 HOH F O      1 
HETATM 2773 O O      . HOH F 4 .  ? -1.40140  5.85355   11.27197  1.000 35.88218 ? 406 HOH F O      1 
HETATM 2774 O O      . HOH F 4 .  ? 20.38102  -9.30794  5.50286   1.000 44.35675 ? 407 HOH F O      1 
HETATM 2775 O O      . HOH F 4 .  ? 24.10444  -5.42481  -7.59962  1.000 37.12149 ? 408 HOH F O      1 
HETATM 2776 O O      . HOH F 4 .  ? 29.01284  1.67540   7.79249   1.000 47.22083 ? 409 HOH F O      1 
HETATM 2777 O O      . HOH F 4 .  ? 1.62093   15.34372  5.66187   1.000 39.67760 ? 410 HOH F O      1 
HETATM 2778 O O      . HOH F 4 .  ? 6.53037   17.48050  0.42876   1.000 41.24990 ? 411 HOH F O      1 
HETATM 2779 O O      . HOH F 4 .  ? 26.713    7.728     0.182     1.000 35.13214 ? 412 HOH F O      1 
HETATM 2780 O O      . HOH F 4 .  ? 12.78451  -1.09129  -13.32629 1.000 64.52086 ? 413 HOH F O      1 
HETATM 2781 O O      . HOH F 4 .  ? -1.28871  8.60544   12.09346  1.000 44.89843 ? 414 HOH F O      1 
HETATM 2782 O O      . HOH F 4 .  ? 23.84311  -6.18861  5.52106   1.000 51.12268 ? 415 HOH F O      1 
HETATM 2783 O O      . HOH F 4 .  ? 2.29985   8.69484   14.33876  1.000 53.05095 ? 416 HOH F O      1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    O "O5'" . DA  A 1  ? 0.37950 0.45008 0.26735 0.03583  0.07793  0.05037  1   DA  C "O5'" 
2    C "C5'" . DA  A 1  ? 0.33824 0.44409 0.34130 0.02776  0.09260  0.02489  1   DA  C "C5'" 
3    C "C4'" . DA  A 1  ? 0.30605 0.41502 0.32354 0.04108  0.08085  0.02365  1   DA  C "C4'" 
4    O "O4'" . DA  A 1  ? 0.29794 0.40687 0.27961 0.04384  0.07367  0.04055  1   DA  C "O4'" 
5    C "C3'" . DA  A 1  ? 0.31325 0.39880 0.30111 0.02575  0.07180  0.01919  1   DA  C "C3'" 
6    O "O3'" . DA  A 1  ? 0.32876 0.38270 0.33007 0.01092  0.06291  0.03506  1   DA  C "O3'" 
7    C "C2'" . DA  A 1  ? 0.29588 0.39830 0.27698 0.01680  0.05201  0.02427  1   DA  C "C2'" 
8    C "C1'" . DA  A 1  ? 0.31408 0.38589 0.31517 0.03464  0.10013  0.02678  1   DA  C "C1'" 
9    N N9    . DA  A 1  ? 0.27770 0.35039 0.30245 0.01467  0.06153  0.01233  1   DA  C N9    
10   C C8    . DA  A 1  ? 0.29691 0.36313 0.34928 0.00607  0.08736  0.01636  1   DA  C C8    
11   N N7    . DA  A 1  ? 0.27183 0.34695 0.27502 0.01056  0.05847  0.00899  1   DA  C N7    
12   C C5    . DA  A 1  ? 0.23622 0.33474 0.22056 -0.00472 0.00454  -0.02298 1   DA  C C5    
13   C C6    . DA  A 1  ? 0.22043 0.31309 0.17473 -0.02403 -0.00704 -0.02657 1   DA  C C6    
14   N N6    . DA  A 1  ? 0.23940 0.30766 0.19166 -0.01495 0.01499  -0.01654 1   DA  C N6    
15   N N1    . DA  A 1  ? 0.26756 0.30002 0.17105 -0.03560 0.01671  -0.03112 1   DA  C N1    
16   C C2    . DA  A 1  ? 0.29940 0.30769 0.21104 -0.01582 0.00545  -0.00799 1   DA  C C2    
17   N N3    . DA  A 1  ? 0.29343 0.32652 0.21853 -0.00629 0.01648  -0.01981 1   DA  C N3    
18   C C4    . DA  A 1  ? 0.25933 0.33171 0.21300 -0.00541 0.01002  -0.01326 1   DA  C C4    
31   P P     . DA  A 2  ? 0.31244 0.37703 0.40676 0.01743  0.04400  0.04064  2   DA  C P     
32   O OP1   . DA  A 2  ? 0.34658 0.41551 0.48228 0.03656  0.12730  0.04908  2   DA  C OP1   
33   O OP2   . DA  A 2  ? 0.35138 0.38898 0.42680 0.02005  0.00208  0.03800  2   DA  C OP2   
34   O "O5'" . DA  A 2  ? 0.33354 0.35919 0.33634 -0.00315 0.04893  0.03240  2   DA  C "O5'" 
35   C "C5'" . DA  A 2  ? 0.36131 0.33276 0.30798 -0.00529 0.10027  -0.01814 2   DA  C "C5'" 
36   C "C4'" . DA  A 2  ? 0.40115 0.30427 0.32733 0.03844  0.08031  -0.01801 2   DA  C "C4'" 
37   O "O4'" . DA  A 2  ? 0.44402 0.29120 0.29331 0.04983  0.06532  -0.03853 2   DA  C "O4'" 
38   C "C3'" . DA  A 2  ? 0.47567 0.29719 0.34803 0.07153  0.11591  0.02031  2   DA  C "C3'" 
39   O "O3'" . DA  A 2  ? 0.61917 0.30897 0.42450 0.09476  0.17464  0.06590  2   DA  C "O3'" 
40   C "C2'" . DA  A 2  ? 0.44517 0.28905 0.28437 0.06575  0.06405  0.01615  2   DA  C "C2'" 
41   C "C1'" . DA  A 2  ? 0.39110 0.29415 0.26040 0.07201  0.03813  -0.00898 2   DA  C "C1'" 
42   N N9    . DA  A 2  ? 0.33852 0.29017 0.23188 0.05240  0.01829  -0.00090 2   DA  C N9    
43   C C8    . DA  A 2  ? 0.33904 0.29934 0.22724 0.04728  -0.03011 -0.00691 2   DA  C C8    
44   N N7    . DA  A 2  ? 0.34206 0.28890 0.23905 0.04551  0.01944  -0.00591 2   DA  C N7    
45   C C5    . DA  A 2  ? 0.34155 0.28364 0.16726 0.02445  0.01651  -0.00852 2   DA  C C5    
46   C C6    . DA  A 2  ? 0.33038 0.28968 0.15091 0.03185  -0.02957 0.00295  2   DA  C C6    
47   N N6    . DA  A 2  ? 0.31017 0.27068 0.16730 0.04655  -0.00874 0.01774  2   DA  C N6    
48   N N1    . DA  A 2  ? 0.33715 0.26866 0.15876 0.01560  -0.02870 -0.01484 2   DA  C N1    
49   C C2    . DA  A 2  ? 0.33422 0.27754 0.23719 0.01769  0.00245  -0.01891 2   DA  C C2    
50   N N3    . DA  A 2  ? 0.33806 0.29016 0.27632 0.03779  0.00516  -0.03595 2   DA  C N3    
51   C C4    . DA  A 2  ? 0.33226 0.29871 0.21172 0.02641  -0.01478 -0.04432 2   DA  C C4    
63   P P     . DT  A 3  ? 0.76437 0.33420 0.48732 0.09455  0.23622  0.09507  3   DT  C P     
64   O OP1   . DT  A 3  ? 0.82550 0.34321 0.55357 0.07482  0.27306  0.10334  3   DT  C OP1   
65   O OP2   . DT  A 3  ? 0.81825 0.36201 0.53380 0.10858  0.24685  0.11676  3   DT  C OP2   
66   O "O5'" . DT  A 3  ? 0.77296 0.33631 0.40770 0.08422  0.21289  0.06700  3   DT  C "O5'" 
67   C "C5'" . DT  A 3  ? 0.75362 0.31948 0.33670 0.09585  0.15409  0.05121  3   DT  C "C5'" 
68   C "C4'" . DT  A 3  ? 0.75012 0.32934 0.28161 0.07919  0.08944  0.03730  3   DT  C "C4'" 
69   O "O4'" . DT  A 3  ? 0.71329 0.31567 0.22795 0.09615  0.02506  0.03396  3   DT  C "O4'" 
70   C "C3'" . DT  A 3  ? 0.77622 0.35549 0.28102 0.08214  0.08314  0.03065  3   DT  C "C3'" 
71   O "O3'" . DT  A 3  ? 0.85236 0.39710 0.29340 0.08050  0.18473  0.05767  3   DT  C "O3'" 
72   C "C2'" . DT  A 3  ? 0.71608 0.33336 0.23729 0.09499  0.02435  0.03056  3   DT  C "C2'" 
73   C "C1'" . DT  A 3  ? 0.66739 0.30842 0.22379 0.09594  -0.00081 0.01731  3   DT  C "C1'" 
74   N N1    . DT  A 3  ? 0.57557 0.29257 0.22407 0.11785  -0.02378 -0.00597 3   DT  C N1    
75   C C2    . DT  A 3  ? 0.53478 0.30248 0.21340 0.06988  -0.05804 -0.02492 3   DT  C C2    
76   O O2    . DT  A 3  ? 0.52599 0.32158 0.20687 0.01986  -0.03762 -0.00548 3   DT  C O2    
77   N N3    . DT  A 3  ? 0.48840 0.26536 0.19909 0.05435  -0.03825 -0.02731 3   DT  C N3    
78   C C4    . DT  A 3  ? 0.48253 0.28023 0.20248 0.08217  -0.04485 -0.02021 3   DT  C C4    
79   O O4    . DT  A 3  ? 0.47392 0.29969 0.20612 0.06304  -0.03923 -0.01458 3   DT  C O4    
80   C C5    . DT  A 3  ? 0.48009 0.30176 0.22347 0.12104  -0.03498 -0.00628 3   DT  C C5    
81   C C7    . DT  A 3  ? 0.48587 0.32537 0.26063 0.13880  -0.03618 0.02527  3   DT  C C7    
82   C C6    . DT  A 3  ? 0.53917 0.30984 0.24398 0.12758  -0.02843 0.00759  3   DT  C C6    
95   P P     . DA  A 4  ? 0.90978 0.43669 0.35523 0.08823  0.22289  0.07249  4   DA  C P     
96   O OP1   . DA  A 4  ? 0.97536 0.45093 0.44217 0.07333  0.29634  0.09177  4   DA  C OP1   
97   O OP2   . DA  A 4  ? 0.93849 0.45208 0.41753 0.13340  0.20730  0.09034  4   DA  C OP2   
98   O "O5'" . DA  A 4  ? 0.81377 0.41639 0.29176 0.08504  0.08683  0.06610  4   DA  C "O5'" 
99   C "C5'" . DA  A 4  ? 0.74536 0.40173 0.30077 0.04504  0.06079  0.01214  4   DA  C "C5'" 
100  C "C4'" . DA  A 4  ? 0.67827 0.39227 0.20489 0.02245  -0.02209 0.01729  4   DA  C "C4'" 
101  O "O4'" . DA  A 4  ? 0.65209 0.37245 0.19545 0.02699  -0.01570 0.04077  4   DA  C "O4'" 
102  C "C3'" . DA  A 4  ? 0.68817 0.41684 0.21809 0.04063  -0.02355 0.00624  4   DA  C "C3'" 
103  O "O3'" . DA  A 4  ? 0.69815 0.47355 0.23982 0.05124  0.01269  -0.01844 4   DA  C "O3'" 
104  C "C2'" . DA  A 4  ? 0.69287 0.39325 0.27483 0.01134  -0.00694 -0.00126 4   DA  C "C2'" 
105  C "C1'" . DA  A 4  ? 0.67743 0.36086 0.26273 0.01530  -0.00328 0.00802  4   DA  C "C1'" 
106  N N9    . DA  A 4  ? 0.67797 0.34943 0.25245 0.02838  -0.02382 -0.01118 4   DA  C N9    
107  C C8    . DA  A 4  ? 0.68093 0.34595 0.26639 0.03226  -0.08069 0.01048  4   DA  C C8    
108  N N7    . DA  A 4  ? 0.67446 0.35132 0.22921 0.02665  -0.15250 -0.01777 4   DA  C N7    
109  C C5    . DA  A 4  ? 0.64854 0.32993 0.23024 0.04040  -0.14793 -0.01340 4   DA  C C5    
110  C C6    . DA  A 4  ? 0.62640 0.32768 0.20926 0.04049  -0.13700 -0.01580 4   DA  C C6    
111  N N6    . DA  A 4  ? 0.63463 0.33960 0.21767 0.05467  -0.14179 -0.03394 4   DA  C N6    
112  N N1    . DA  A 4  ? 0.61120 0.31412 0.20659 0.03876  -0.13525 0.00397  4   DA  C N1    
113  C C2    . DA  A 4  ? 0.63829 0.31676 0.19444 0.03307  -0.10786 -0.01012 4   DA  C C2    
114  N N3    . DA  A 4  ? 0.64944 0.31673 0.22410 0.04014  -0.10332 -0.02156 4   DA  C N3    
115  C C4    . DA  A 4  ? 0.67194 0.32707 0.22798 0.03054  -0.06801 -0.01187 4   DA  C C4    
127  P P     . DA  A 5  ? 0.68915 0.50454 0.26050 0.04621  0.08363  -0.02023 5   DA  C P     
128  O OP1   . DA  A 5  ? 0.73795 0.51942 0.35777 0.05885  0.14454  -0.05660 5   DA  C OP1   
129  O OP2   . DA  A 5  ? 0.66114 0.52775 0.27073 0.15135  0.05490  0.00588  5   DA  C OP2   
130  O "O5'" . DA  A 5  ? 0.62601 0.47749 0.27061 -0.00462 0.08935  0.00982  5   DA  C "O5'" 
131  C "C5'" . DA  A 5  ? 0.53507 0.45579 0.25034 -0.05734 0.05754  0.00002  5   DA  C "C5'" 
132  C "C4'" . DA  A 5  ? 0.45834 0.44575 0.21522 -0.07589 0.01762  -0.02150 5   DA  C "C4'" 
133  O "O4'" . DA  A 5  ? 0.43214 0.43389 0.22895 -0.09859 -0.03719 0.01700  5   DA  C "O4'" 
134  C "C3'" . DA  A 5  ? 0.43468 0.42857 0.22850 -0.06446 0.01185  0.00441  5   DA  C "C3'" 
135  O "O3'" . DA  A 5  ? 0.39138 0.44924 0.23811 -0.06765 -0.01915 -0.03825 5   DA  C "O3'" 
136  C "C2'" . DA  A 5  ? 0.41232 0.40774 0.24910 -0.04422 -0.01866 0.04081  5   DA  C "C2'" 
137  C "C1'" . DA  A 5  ? 0.38647 0.40644 0.24243 -0.05083 -0.04033 0.05865  5   DA  C "C1'" 
138  N N9    . DA  A 5  ? 0.36484 0.38341 0.22439 -0.00827 -0.04997 0.05567  5   DA  C N9    
139  C C8    . DA  A 5  ? 0.37084 0.38824 0.24474 -0.03848 -0.05609 0.01804  5   DA  C C8    
140  N N7    . DA  A 5  ? 0.38817 0.39342 0.20997 0.00158  -0.05153 0.03586  5   DA  C N7    
141  C C5    . DA  A 5  ? 0.35435 0.38308 0.17458 0.02527  -0.09042 0.02812  5   DA  C C5    
142  C C6    . DA  A 5  ? 0.33662 0.39047 0.17747 0.02676  -0.07363 0.02148  5   DA  C C6    
143  N N6    . DA  A 5  ? 0.33629 0.40456 0.17264 0.02864  -0.06378 0.01175  5   DA  C N6    
144  N N1    . DA  A 5  ? 0.33468 0.39301 0.18408 0.02884  -0.07717 0.02086  5   DA  C N1    
145  C C2    . DA  A 5  ? 0.35887 0.39526 0.22784 0.02953  -0.07759 0.03462  5   DA  C C2    
146  N N3    . DA  A 5  ? 0.37122 0.39098 0.23232 0.02122  -0.04687 0.04599  5   DA  C N3    
147  C C4    . DA  A 5  ? 0.34597 0.38110 0.23962 0.00811  -0.04326 0.03204  5   DA  C C4    
159  P P     . DG  A 6  ? 0.34936 0.46797 0.24338 -0.04393 -0.02716 -0.02097 6   DG  C P     
160  O OP1   . DG  A 6  ? 0.42191 0.47149 0.29218 -0.03378 -0.00595 -0.00461 6   DG  C OP1   
161  O OP2   . DG  A 6  ? 0.38828 0.50567 0.28835 -0.07924 0.00840  0.00690  6   DG  C OP2   
162  O "O5'" . DG  A 6  ? 0.31148 0.50597 0.22845 -0.03592 -0.05293 -0.00598 6   DG  C "O5'" 
163  C "C5'" . DG  A 6  ? 0.29077 0.46635 0.25456 -0.04214 -0.05489 0.00048  6   DG  C "C5'" 
164  C "C4'" . DG  A 6  ? 0.28494 0.45860 0.30144 -0.01831 -0.04240 -0.00879 6   DG  C "C4'" 
165  O "O4'" . DG  A 6  ? 0.25431 0.47398 0.25834 -0.00617 -0.04283 -0.00024 6   DG  C "O4'" 
166  C "C3'" . DG  A 6  ? 0.30192 0.43757 0.35374 -0.01133 -0.06350 -0.02759 6   DG  C "C3'" 
167  O "O3'" . DG  A 6  ? 0.31950 0.42111 0.37949 0.04155  -0.11379 -0.02272 6   DG  C "O3'" 
168  C "C2'" . DG  A 6  ? 0.29586 0.45356 0.31039 -0.01321 -0.06139 -0.01467 6   DG  C "C2'" 
169  C "C1'" . DG  A 6  ? 0.29210 0.46898 0.27880 -0.00224 -0.03122 0.02134  6   DG  C "C1'" 
170  N N9    . DG  A 6  ? 0.27467 0.46480 0.29869 -0.02347 -0.03297 0.04867  6   DG  C N9    
171  C C8    . DG  A 6  ? 0.28896 0.46176 0.26487 -0.02382 -0.01569 0.05917  6   DG  C C8    
172  N N7    . DG  A 6  ? 0.28533 0.45554 0.22901 -0.02211 -0.05044 0.04851  6   DG  C N7    
173  C C5    . DG  A 6  ? 0.30340 0.45519 0.21491 -0.02867 -0.04697 0.04791  6   DG  C C5    
174  C C6    . DG  A 6  ? 0.31750 0.46079 0.16508 0.00262  -0.09202 0.04363  6   DG  C C6    
175  O O6    . DG  A 6  ? 0.32087 0.48235 0.19106 0.01729  -0.02725 0.02370  6   DG  C O6    
176  N N1    . DG  A 6  ? 0.34744 0.47483 0.17947 -0.02623 -0.06449 0.03908  6   DG  C N1    
177  C C2    . DG  A 6  ? 0.33499 0.49252 0.20983 -0.02766 -0.04435 0.03272  6   DG  C C2    
178  N N2    . DG  A 6  ? 0.35090 0.50637 0.22398 -0.04171 -0.07036 0.01479  6   DG  C N2    
179  N N3    . DG  A 6  ? 0.30866 0.48751 0.24131 -0.03857 -0.05591 0.05161  6   DG  C N3    
180  C C4    . DG  A 6  ? 0.25163 0.46220 0.25068 -0.05560 -0.06017 0.05365  6   DG  C C4    
192  P P     . DC  A 7  ? 0.31588 0.42582 0.38580 0.03420  -0.12396 -0.03628 7   DC  C P     
193  O OP1   . DC  A 7  ? 0.37776 0.43279 0.38226 0.08445  -0.10018 -0.02499 7   DC  C OP1   
194  O OP2   . DC  A 7  ? 0.31474 0.41805 0.38149 -0.04308 -0.13604 -0.01653 7   DC  C OP2   
195  O "O5'" . DC  A 7  ? 0.30949 0.38959 0.36444 0.01968  -0.10747 -0.02984 7   DC  C "O5'" 
196  C "C5'" . DC  A 7  ? 0.37019 0.38204 0.33020 0.02945  -0.08321 0.00543  7   DC  C "C5'" 
197  C "C4'" . DC  A 7  ? 0.38521 0.36571 0.29367 -0.03220 -0.10888 -0.00227 7   DC  C "C4'" 
198  O "O4'" . DC  A 7  ? 0.37056 0.36013 0.26803 -0.04128 -0.08109 0.02766  7   DC  C "O4'" 
199  C "C3'" . DC  A 7  ? 0.39993 0.37729 0.35141 -0.08466 -0.12286 0.00267  7   DC  C "C3'" 
200  O "O3'" . DC  A 7  ? 0.46432 0.40693 0.43557 -0.07771 -0.14125 -0.05051 7   DC  C "O3'" 
201  C "C2'" . DC  A 7  ? 0.42342 0.36998 0.31115 -0.08892 -0.04414 0.03144  7   DC  C "C2'" 
202  C "C1'" . DC  A 7  ? 0.34981 0.37535 0.27098 -0.07796 -0.07233 0.05706  7   DC  C "C1'" 
203  N N1    . DC  A 7  ? 0.34348 0.39867 0.24263 -0.07213 -0.07511 0.06316  7   DC  C N1    
204  C C2    . DC  A 7  ? 0.32518 0.40856 0.21797 -0.05844 -0.09934 0.12747  7   DC  C C2    
205  O O2    . DC  A 7  ? 0.35990 0.44003 0.31883 -0.06716 -0.06577 0.15044  7   DC  C O2    
206  N N3    . DC  A 7  ? 0.37704 0.43287 0.19175 -0.04257 -0.07730 0.11409  7   DC  C N3    
207  C C4    . DC  A 7  ? 0.33908 0.41797 0.19247 -0.05654 -0.10073 0.06395  7   DC  C C4    
208  N N4    . DC  A 7  ? 0.39806 0.43261 0.18477 -0.05978 -0.07030 0.03246  7   DC  C N4    
209  C C5    . DC  A 7  ? 0.33025 0.40574 0.21942 -0.05980 -0.09686 0.05183  7   DC  C C5    
210  C C6    . DC  A 7  ? 0.32313 0.39902 0.22660 -0.05294 -0.08214 0.05142  7   DC  C C6    
222  P P     . DG  A 8  ? 0.57678 0.41814 0.51814 -0.05542 -0.11070 -0.06920 8   DG  C P     
223  O OP1   . DG  A 8  ? 0.60829 0.38359 0.62787 -0.01942 -0.09303 -0.01678 8   DG  C OP1   
224  O OP2   . DG  A 8  ? 0.53977 0.43000 0.53655 -0.07221 -0.13894 -0.10585 8   DG  C OP2   
225  O "O5'" . DG  A 8  ? 0.58363 0.41019 0.47969 -0.09316 -0.15835 -0.03584 8   DG  C "O5'" 
226  C "C5'" . DG  A 8  ? 0.56947 0.40660 0.45447 -0.12223 -0.24576 -0.01205 8   DG  C "C5'" 
227  C "C4'" . DG  A 8  ? 0.57792 0.41754 0.48455 -0.13738 -0.25715 0.01974  8   DG  C "C4'" 
228  O "O4'" . DG  A 8  ? 0.52529 0.41111 0.50111 -0.13294 -0.28928 0.06799  8   DG  C "O4'" 
229  C "C3'" . DG  A 8  ? 0.61702 0.43602 0.51704 -0.13149 -0.24289 0.04555  8   DG  C "C3'" 
230  O "O3'" . DG  A 8  ? 0.63448 0.46416 0.59413 -0.14131 -0.25512 0.01592  8   DG  C "O3'" 
231  C "C2'" . DG  A 8  ? 0.59608 0.42985 0.42720 -0.12775 -0.28292 0.06909  8   DG  C "C2'" 
232  C "C1'" . DG  A 8  ? 0.55362 0.42390 0.47537 -0.12992 -0.28836 0.08259  8   DG  C "C1'" 
233  N N9    . DG  A 8  ? 0.50085 0.40295 0.44519 -0.10700 -0.26902 0.11591  8   DG  C N9    
234  C C8    . DG  A 8  ? 0.50692 0.42019 0.47891 -0.09981 -0.27560 0.14200  8   DG  C C8    
235  N N7    . DG  A 8  ? 0.49569 0.41907 0.46645 -0.12999 -0.27102 0.13512  8   DG  C N7    
236  C C5    . DG  A 8  ? 0.52507 0.43367 0.43118 -0.13916 -0.26235 0.13834  8   DG  C C5    
237  C C6    . DG  A 8  ? 0.50819 0.44304 0.37101 -0.14240 -0.23464 0.11052  8   DG  C C6    
238  O O6    . DG  A 8  ? 0.53990 0.45344 0.39980 -0.16868 -0.24545 0.14766  8   DG  C O6    
239  N N1    . DG  A 8  ? 0.53062 0.46843 0.36416 -0.14934 -0.23338 0.10831  8   DG  C N1    
240  C C2    . DG  A 8  ? 0.51780 0.47684 0.34953 -0.13332 -0.22655 0.09574  8   DG  C C2    
241  N N2    . DG  A 8  ? 0.55981 0.52420 0.32530 -0.15134 -0.20812 0.11390  8   DG  C N2    
242  N N3    . DG  A 8  ? 0.51317 0.45729 0.37562 -0.08561 -0.23329 0.12770  8   DG  C N3    
243  C C4    . DG  A 8  ? 0.49739 0.43693 0.42718 -0.12223 -0.25764 0.12484  8   DG  C C4    
255  P P     . DG  A 9  ? 0.64039 0.47858 0.68626 -0.14258 -0.26242 -0.01581 9   DG  C P     
256  O OP1   . DG  A 9  ? 0.65943 0.48462 0.74260 -0.11492 -0.21630 0.00077  9   DG  C OP1   
257  O OP2   . DG  A 9  ? 0.65116 0.49661 0.69597 -0.14268 -0.25873 -0.02408 9   DG  C OP2   
258  O "O5'" . DG  A 9  ? 0.67584 0.44610 0.63124 -0.10103 -0.22077 -0.01703 9   DG  C "O5'" 
259  C "C5'" . DG  A 9  ? 0.71326 0.43421 0.59592 -0.03531 -0.15805 0.00711  9   DG  C "C5'" 
260  C "C4'" . DG  A 9  ? 0.72351 0.43107 0.56887 0.03110  -0.11616 0.03679  9   DG  C "C4'" 
261  O "O4'" . DG  A 9  ? 0.75249 0.45256 0.54527 0.07044  -0.04846 0.07787  9   DG  C "O4'" 
262  C "C3'" . DG  A 9  ? 0.66320 0.41626 0.56457 0.07049  -0.16514 0.06046  9   DG  C "C3'" 
263  O "O3'" . DG  A 9  ? 0.66628 0.41483 0.66970 0.07784  -0.12129 0.03801  9   DG  C "O3'" 
264  C "C2'" . DG  A 9  ? 0.64067 0.43749 0.52219 0.08094  -0.16003 0.04984  9   DG  C "C2'" 
265  C "C1'" . DG  A 9  ? 0.62188 0.45745 0.49567 0.08056  -0.09645 0.07979  9   DG  C "C1'" 
266  N N9    . DG  A 9  ? 0.44018 0.48463 0.42405 0.05995  -0.09174 0.09563  9   DG  C N9    
267  C C8    . DG  A 9  ? 0.36173 0.48549 0.37310 0.07357  -0.08494 0.10546  9   DG  C C8    
268  N N7    . DG  A 9  ? 0.33293 0.48812 0.32856 0.09871  -0.09768 0.09163  9   DG  C N7    
269  C C5    . DG  A 9  ? 0.31359 0.47680 0.28530 0.03285  -0.08525 0.10560  9   DG  C C5    
270  C C6    . DG  A 9  ? 0.25719 0.47099 0.26465 0.05061  -0.01198 0.10560  9   DG  C C6    
271  O O6    . DG  A 9  ? 0.23084 0.43987 0.24840 -0.02123 0.00358  0.10105  9   DG  C O6    
272  N N1    . DG  A 9  ? 0.24059 0.51433 0.31046 0.00108  -0.01577 0.06750  9   DG  C N1    
273  C C2    . DG  A 9  ? 0.27220 0.59464 0.42080 0.07008  0.00472  0.10443  9   DG  C C2    
274  N N2    . DG  A 9  ? 0.34836 0.70342 0.45808 0.09112  0.04887  0.11459  9   DG  C N2    
275  N N3    . DG  A 9  ? 0.32260 0.56589 0.44330 0.08649  0.01673  0.11945  9   DG  C N3    
276  C C4    . DG  A 9  ? 0.33009 0.51361 0.36048 0.07914  -0.07971 0.12552  9   DG  C C4    
288  P P     . DA  A 10 ? 0.62407 0.42841 0.77515 0.06116  -0.11419 0.02105  10  DA  C P     
289  O OP1   . DA  A 10 ? 0.64954 0.44855 0.84635 0.06519  -0.11888 0.03309  10  DA  C OP1   
290  O OP2   . DA  A 10 ? 0.60541 0.45498 0.77830 0.06643  -0.14300 -0.01966 10  DA  C OP2   
291  O "O5'" . DA  A 10 ? 0.57993 0.40423 0.71236 0.05993  -0.08772 0.06488  10  DA  C "O5'" 
292  C "C5'" . DA  A 10 ? 0.53103 0.38145 0.63209 0.05235  -0.09234 0.10138  10  DA  C "C5'" 
293  C "C4'" . DA  A 10 ? 0.49484 0.38399 0.52194 0.03631  -0.07008 0.13459  10  DA  C "C4'" 
294  O "O4'" . DA  A 10 ? 0.48935 0.38428 0.44254 0.03624  -0.08714 0.10067  10  DA  C "O4'" 
295  C "C3'" . DA  A 10 ? 0.45964 0.38869 0.50391 0.00945  -0.05719 0.13209  10  DA  C "C3'" 
296  O "O3'" . DA  A 10 ? 0.46717 0.42838 0.55342 -0.01162 0.02638  0.14557  10  DA  C "O3'" 
297  C "C2'" . DA  A 10 ? 0.44020 0.37136 0.45957 0.00262  -0.08308 0.07970  10  DA  C "C2'" 
298  C "C1'" . DA  A 10 ? 0.44814 0.35971 0.42111 0.02197  -0.09702 0.06281  10  DA  C "C1'" 
299  N N9    . DA  A 10 ? 0.41809 0.32609 0.37040 0.01840  -0.09499 0.03562  10  DA  C N9    
300  C C8    . DA  A 10 ? 0.43957 0.31672 0.33518 0.01417  -0.10668 0.02286  10  DA  C C8    
301  N N7    . DA  A 10 ? 0.41007 0.29599 0.33410 0.02263  -0.14394 0.01967  10  DA  C N7    
302  C C5    . DA  A 10 ? 0.39532 0.29393 0.29253 0.03110  -0.14271 0.00739  10  DA  C C5    
303  C C6    . DA  A 10 ? 0.38642 0.30433 0.25496 0.03267  -0.14117 0.01093  10  DA  C C6    
304  N N6    . DA  A 10 ? 0.41127 0.31674 0.25770 0.04652  -0.13296 0.00106  10  DA  C N6    
305  N N1    . DA  A 10 ? 0.36644 0.28854 0.26516 0.02394  -0.12490 0.01431  10  DA  C N1    
306  C C2    . DA  A 10 ? 0.40189 0.29935 0.26281 0.03621  -0.08266 0.02130  10  DA  C C2    
307  N N3    . DA  A 10 ? 0.36796 0.30292 0.24906 0.01837  -0.11779 0.00928  10  DA  C N3    
308  C C4    . DA  A 10 ? 0.39769 0.29679 0.27791 0.02184  -0.11754 0.02778  10  DA  C C4    
320  P P     . DA  A 11 ? 0.42547 0.45245 0.58346 -0.03691 0.02815  0.15784  11  DA  C P     
321  O OP1   . DA  A 11 ? 0.44769 0.49243 0.61816 -0.03983 0.05650  0.15448  11  DA  C OP1   
322  O OP2   . DA  A 11 ? 0.41823 0.44327 0.59686 -0.02282 0.01316  0.15498  11  DA  C OP2   
323  O "O5'" . DA  A 11 ? 0.31997 0.40201 0.50652 -0.01454 -0.02158 0.15620  11  DA  C "O5'" 
324  C "C5'" . DA  A 11 ? 0.31972 0.40300 0.43895 -0.01400 0.04744  0.11707  11  DA  C "C5'" 
325  C "C4'" . DA  A 11 ? 0.26876 0.39179 0.34138 0.00640  -0.00189 0.08951  11  DA  C "C4'" 
326  O "O4'" . DA  A 11 ? 0.27088 0.40234 0.27087 -0.00023 -0.00785 0.09250  11  DA  C "O4'" 
327  C "C3'" . DA  A 11 ? 0.25158 0.37666 0.34726 -0.01421 -0.00525 0.05501  11  DA  C "C3'" 
328  O "O3'" . DA  A 11 ? 0.29123 0.37400 0.35894 0.05884  -0.02084 0.05673  11  DA  C "O3'" 
329  C "C2'" . DA  A 11 ? 0.22380 0.37549 0.32590 -0.04196 -0.02760 0.05246  11  DA  C "C2'" 
330  C "C1'" . DA  A 11 ? 0.23444 0.37210 0.28891 -0.01930 -0.02227 0.05972  11  DA  C "C1'" 
331  N N9    . DA  A 11 ? 0.22899 0.33831 0.24771 -0.01647 -0.00846 0.03754  11  DA  C N9    
332  C C8    . DA  A 11 ? 0.23666 0.33963 0.25789 -0.01610 -0.00325 0.04220  11  DA  C C8    
333  N N7    . DA  A 11 ? 0.23673 0.32442 0.24614 -0.02986 -0.02823 0.04023  11  DA  C N7    
334  C C5    . DA  A 11 ? 0.21321 0.31605 0.21548 -0.02689 -0.04746 0.02189  11  DA  C C5    
335  C C6    . DA  A 11 ? 0.19913 0.31041 0.17048 -0.02252 -0.03930 0.02447  11  DA  C C6    
336  N N6    . DA  A 11 ? 0.20635 0.33868 0.21605 0.00897  -0.00968 0.03842  11  DA  C N6    
337  N N1    . DA  A 11 ? 0.18645 0.29312 0.18262 -0.01615 -0.01381 -0.00189 11  DA  C N1    
338  C C2    . DA  A 11 ? 0.18930 0.30705 0.17795 0.00031  -0.04342 -0.00400 11  DA  C C2    
339  N N3    . DA  A 11 ? 0.18076 0.30562 0.21568 0.00174  -0.02536 0.01467  11  DA  C N3    
340  C C4    . DA  A 11 ? 0.20156 0.32445 0.19436 -0.02479 -0.01845 0.03699  11  DA  C C4    
352  P P     . DG  A 12 ? 0.24607 0.35244 0.34727 0.03790  -0.04829 0.01872  12  DG  C P     
353  O OP1   . DG  A 12 ? 0.26486 0.36490 0.39111 0.05197  -0.01048 0.05844  12  DG  C OP1   
354  O OP2   . DG  A 12 ? 0.24157 0.35855 0.39013 0.06397  -0.03333 -0.02333 12  DG  C OP2   
355  O "O5'" . DG  A 12 ? 0.26020 0.34569 0.28691 -0.00106 -0.03302 -0.00742 12  DG  C "O5'" 
356  C "C5'" . DG  A 12 ? 0.24124 0.35361 0.24836 0.02041  0.00032  0.01006  12  DG  C "C5'" 
357  C "C4'" . DG  A 12 ? 0.22979 0.37971 0.21286 0.01019  0.00593  -0.00422 12  DG  C "C4'" 
358  O "O4'" . DG  A 12 ? 0.18755 0.40452 0.22090 -0.00391 -0.02210 -0.01262 12  DG  C "O4'" 
359  C "C3'" . DG  A 12 ? 0.20607 0.38041 0.18921 0.02348  -0.01419 -0.00966 12  DG  C "C3'" 
360  O "O3'" . DG  A 12 ? 0.22421 0.39151 0.22090 0.01532  -0.00514 -0.02360 12  DG  C "O3'" 
361  C "C2'" . DG  A 12 ? 0.16908 0.38325 0.19408 0.01866  -0.01231 -0.01732 12  DG  C "C2'" 
362  C "C1'" . DG  A 12 ? 0.14637 0.36870 0.22182 0.02772  -0.00766 0.00216  12  DG  C "C1'" 
363  N N9    . DG  A 12 ? 0.16677 0.33174 0.22070 0.01416  -0.01630 0.01154  12  DG  C N9    
364  C C8    . DG  A 12 ? 0.18978 0.34946 0.21104 -0.00312 -0.02855 0.02902  12  DG  C C8    
365  N N7    . DG  A 12 ? 0.16303 0.35474 0.20032 -0.00284 -0.03014 0.02016  12  DG  C N7    
366  C C5    . DG  A 12 ? 0.15429 0.32713 0.19849 -0.01621 -0.03291 0.00048  12  DG  C C5    
367  C C6    . DG  A 12 ? 0.16529 0.30017 0.19337 -0.01515 -0.03482 0.00519  12  DG  C C6    
368  O O6    . DG  A 12 ? 0.19636 0.30203 0.23781 -0.02403 -0.03244 -0.00384 12  DG  C O6    
369  N N1    . DG  A 12 ? 0.17956 0.28476 0.18202 -0.01711 -0.03031 -0.00334 12  DG  C N1    
370  C C2    . DG  A 12 ? 0.17153 0.28656 0.18597 -0.01171 -0.01937 -0.01723 12  DG  C C2    
371  N N2    . DG  A 12 ? 0.16171 0.28179 0.21982 -0.00522 -0.01229 -0.02862 12  DG  C N2    
372  N N3    . DG  A 12 ? 0.16490 0.29298 0.18405 -0.00346 -0.00894 0.01719  12  DG  C N3    
373  C C4    . DG  A 12 ? 0.15507 0.31461 0.19567 0.00729  -0.00600 0.00806  12  DG  C C4    
385  P P     . DT  A 13 ? 0.25144 0.41201 0.24644 0.04017  0.01902  0.00687  13  DT  C P     
386  O OP1   . DT  A 13 ? 0.31929 0.40187 0.31048 0.06450  0.06960  0.00244  13  DT  C OP1   
387  O OP2   . DT  A 13 ? 0.21032 0.45020 0.24211 0.02180  -0.01516 0.02028  13  DT  C OP2   
388  O "O5'" . DT  A 13 ? 0.25822 0.38890 0.26707 -0.00242 0.02863  -0.01930 13  DT  C "O5'" 
389  C "C5'" . DT  A 13 ? 0.27459 0.38070 0.22505 0.00988  0.04926  -0.02590 13  DT  C "C5'" 
390  C "C4'" . DT  A 13 ? 0.24162 0.36768 0.21932 0.00817  -0.00792 -0.06153 13  DT  C "C4'" 
391  O "O4'" . DT  A 13 ? 0.26335 0.36234 0.23082 0.01244  0.00380  -0.08534 13  DT  C "O4'" 
392  C "C3'" . DT  A 13 ? 0.24901 0.37562 0.23102 -0.00898 -0.00383 -0.07700 13  DT  C "C3'" 
393  O "O3'" . DT  A 13 ? 0.31013 0.37459 0.27237 -0.02827 -0.01288 -0.06809 13  DT  C "O3'" 
394  C "C2'" . DT  A 13 ? 0.22103 0.38901 0.23784 0.02056  -0.01254 -0.07448 13  DT  C "C2'" 
395  C "C1'" . DT  A 13 ? 0.21321 0.36819 0.20685 0.03065  0.00999  -0.06137 13  DT  C "C1'" 
396  N N1    . DT  A 13 ? 0.17920 0.37066 0.22039 0.01215  -0.00698 -0.04159 13  DT  C N1    
397  C C2    . DT  A 13 ? 0.14710 0.36392 0.20536 0.00460  -0.02578 -0.03693 13  DT  C C2    
398  O O2    . DT  A 13 ? 0.18508 0.37137 0.22108 -0.00121 -0.01759 -0.02340 13  DT  C O2    
399  N N3    . DT  A 13 ? 0.17825 0.35132 0.16193 -0.01930 -0.00509 -0.04333 13  DT  C N3    
400  C C4    . DT  A 13 ? 0.18397 0.36659 0.18913 -0.02635 -0.01552 -0.05734 13  DT  C C4    
401  O O4    . DT  A 13 ? 0.19745 0.36621 0.18501 -0.00720 -0.02066 -0.02034 13  DT  C O4    
402  C C5    . DT  A 13 ? 0.19111 0.37491 0.20778 -0.01688 0.02102  -0.03653 13  DT  C C5    
403  C C7    . DT  A 13 ? 0.20460 0.37621 0.24095 -0.01947 0.04129  -0.00824 13  DT  C C7    
404  C C6    . DT  A 13 ? 0.12832 0.37808 0.22469 0.01957  -0.02493 -0.05646 13  DT  C C6    
417  P P     . DG  A 14 ? 0.37872 0.35076 0.28807 -0.03989 0.03607  -0.02853 14  DG  C P     
418  O OP1   . DG  A 14 ? 0.39333 0.32678 0.39924 -0.02741 0.05064  -0.04770 14  DG  C OP1   
419  O OP2   . DG  A 14 ? 0.34394 0.35401 0.34195 -0.04288 -0.02811 0.00712  14  DG  C OP2   
420  O "O5'" . DG  A 14 ? 0.45148 0.39122 0.30634 -0.02702 0.10310  0.00732  14  DG  C "O5'" 
421  C "C5'" . DG  A 14 ? 0.47790 0.38319 0.32979 -0.04403 0.09714  0.00064  14  DG  C "C5'" 
422  C "C4'" . DG  A 14 ? 0.46924 0.34449 0.28521 -0.06106 0.06794  -0.03895 14  DG  C "C4'" 
423  O "O4'" . DG  A 14 ? 0.44943 0.35726 0.27887 -0.07494 -0.03922 -0.00845 14  DG  C "O4'" 
424  C "C3'" . DG  A 14 ? 0.47703 0.31373 0.30265 -0.07690 0.09280  -0.03869 14  DG  C "C3'" 
425  O "O3'" . DG  A 14 ? 0.53728 0.30458 0.31178 -0.12245 0.12666  -0.05081 14  DG  C "O3'" 
426  C "C2'" . DG  A 14 ? 0.43763 0.31736 0.27880 -0.07025 0.04799  -0.03817 14  DG  C "C2'" 
427  C "C1'" . DG  A 14 ? 0.37890 0.32051 0.24864 -0.06672 0.02156  -0.04407 14  DG  C "C1'" 
428  N N9    . DG  A 14 ? 0.27719 0.32329 0.23172 -0.03802 -0.01952 -0.00064 14  DG  C N9    
429  C C8    . DG  A 14 ? 0.24098 0.34455 0.23456 -0.03656 -0.00001 -0.00097 14  DG  C C8    
430  N N7    . DG  A 14 ? 0.21412 0.35136 0.19368 -0.00993 -0.04106 -0.00523 14  DG  C N7    
431  C C5    . DG  A 14 ? 0.22988 0.34088 0.17442 -0.02993 -0.05541 -0.04044 14  DG  C C5    
432  C C6    . DG  A 14 ? 0.25743 0.34381 0.16215 -0.01191 -0.04145 -0.04496 14  DG  C C6    
433  O O6    . DG  A 14 ? 0.24634 0.33809 0.18534 -0.03358 -0.01894 -0.01071 14  DG  C O6    
434  N N1    . DG  A 14 ? 0.27467 0.34688 0.20466 0.01657  -0.01044 -0.03011 14  DG  C N1    
435  C C2    . DG  A 14 ? 0.31203 0.32292 0.18935 0.01733  0.00626  -0.03640 14  DG  C C2    
436  N N2    . DG  A 14 ? 0.38726 0.32304 0.18382 0.01857  0.00777  -0.03809 14  DG  C N2    
437  N N3    . DG  A 14 ? 0.32575 0.33833 0.19075 -0.00225 -0.01104 -0.03862 14  DG  C N3    
438  C C4    . DG  A 14 ? 0.26260 0.33158 0.20063 -0.02128 -0.00515 -0.02827 14  DG  C C4    
450  P P     . DG  A 15 ? 0.64345 0.31458 0.33879 -0.06633 0.20455  -0.00796 15  DG  C P     
451  O OP1   . DG  A 15 ? 0.68610 0.32502 0.38541 -0.07320 0.18311  0.02295  15  DG  C OP1   
452  O OP2   . DG  A 15 ? 0.62541 0.32593 0.32852 0.00946  0.19703  -0.00783 15  DG  C OP2   
453  O "O5'" . DG  A 15 ? 0.59150 0.30459 0.29575 -0.07995 0.15016  -0.03942 15  DG  C "O5'" 
454  C "C5'" . DG  A 15 ? 0.53151 0.30022 0.31294 -0.10674 0.13517  -0.07208 15  DG  C "C5'" 
455  C "C4'" . DG  A 15 ? 0.45279 0.28944 0.31587 -0.08739 0.09994  -0.04556 15  DG  C "C4'" 
456  O "O4'" . DG  A 15 ? 0.36488 0.30725 0.27572 -0.10748 0.06646  -0.03294 15  DG  C "O4'" 
457  C "C3'" . DG  A 15 ? 0.42185 0.29767 0.29725 -0.06618 0.06994  -0.05411 15  DG  C "C3'" 
458  O "O3'" . DG  A 15 ? 0.47186 0.34558 0.27323 -0.09740 0.10080  -0.03948 15  DG  C "O3'" 
459  C "C2'" . DG  A 15 ? 0.35918 0.29044 0.30968 -0.06414 0.06336  -0.02658 15  DG  C "C2'" 
460  C "C1'" . DG  A 15 ? 0.32430 0.30037 0.26359 -0.07695 0.03952  -0.02926 15  DG  C "C1'" 
461  N N9    . DG  A 15 ? 0.27307 0.29989 0.21279 -0.06404 0.01713  -0.03185 15  DG  C N9    
462  C C8    . DG  A 15 ? 0.26551 0.31764 0.20246 -0.05192 0.01963  -0.02990 15  DG  C C8    
463  N N7    . DG  A 15 ? 0.20761 0.32524 0.20594 -0.02155 0.01190  -0.00831 15  DG  C N7    
464  C C5    . DG  A 15 ? 0.23630 0.31729 0.16702 -0.03967 -0.01121 -0.00042 15  DG  C C5    
465  C C6    . DG  A 15 ? 0.23857 0.31843 0.17792 -0.03452 -0.03031 0.00237  15  DG  C C6    
466  O O6    . DG  A 15 ? 0.25070 0.31045 0.17789 -0.04303 -0.01668 0.00161  15  DG  C O6    
467  N N1    . DG  A 15 ? 0.21026 0.30948 0.17744 -0.03023 0.00086  -0.00767 15  DG  C N1    
468  C C2    . DG  A 15 ? 0.21559 0.29785 0.20683 -0.03133 0.00985  -0.00530 15  DG  C C2    
469  N N2    . DG  A 15 ? 0.20811 0.31231 0.24154 -0.03143 -0.00366 -0.00945 15  DG  C N2    
470  N N3    . DG  A 15 ? 0.23932 0.29975 0.17648 -0.03336 0.00170  -0.01069 15  DG  C N3    
471  C C4    . DG  A 15 ? 0.24625 0.29781 0.19007 -0.05593 0.02142  -0.00182 15  DG  C C4    
483  P P     . DG  A 16 ? 0.60643 0.37062 0.31605 -0.10745 0.15309  -0.02789 16  DG  C P     
484  O OP1   . DG  A 16 ? 0.61490 0.40413 0.37610 -0.11769 0.15185  -0.00987 16  DG  C OP1   
485  O OP2   . DG  A 16 ? 0.67407 0.38649 0.30554 -0.06805 0.12941  -0.01549 16  DG  C OP2   
486  O "O5'" . DG  A 16 ? 0.60571 0.38977 0.34572 -0.09599 0.17287  -0.04205 16  DG  C "O5'" 
487  C "C5'" . DG  A 16 ? 0.54160 0.39189 0.34757 -0.08055 0.17738  -0.05359 16  DG  C "C5'" 
488  C "C4'" . DG  A 16 ? 0.44885 0.36550 0.35205 -0.08303 0.15757  -0.07925 16  DG  C "C4'" 
489  O "O4'" . DG  A 16 ? 0.38553 0.33229 0.30289 -0.10271 0.07030  -0.06818 16  DG  C "O4'" 
490  C "C3'" . DG  A 16 ? 0.41372 0.38402 0.44786 -0.07309 0.13557  -0.07452 16  DG  C "C3'" 
491  O "O3'" . DG  A 16 ? 0.36797 0.42488 0.54482 -0.07496 0.09206  -0.09733 16  DG  C "O3'" 
492  C "C2'" . DG  A 16 ? 0.37536 0.34966 0.37241 -0.07280 0.14257  -0.07561 16  DG  C "C2'" 
493  C "C1'" . DG  A 16 ? 0.32837 0.32251 0.31450 -0.05569 0.08187  -0.05222 16  DG  C "C1'" 
494  N N9    . DG  A 16 ? 0.29615 0.27272 0.23505 -0.03558 0.03178  -0.02937 16  DG  C N9    
495  C C8    . DG  A 16 ? 0.29202 0.25466 0.22768 -0.03201 -0.01018 -0.02327 16  DG  C C8    
496  N N7    . DG  A 16 ? 0.28673 0.24417 0.18461 -0.03208 -0.04024 -0.00416 16  DG  C N7    
497  C C5    . DG  A 16 ? 0.23905 0.25145 0.20198 -0.02189 -0.05040 -0.01653 16  DG  C C5    
498  C C6    . DG  A 16 ? 0.22627 0.26084 0.19384 0.00056  -0.02273 0.00634  16  DG  C C6    
499  O O6    . DG  A 16 ? 0.26157 0.27023 0.20153 -0.00205 -0.00273 0.01421  16  DG  C O6    
500  N N1    . DG  A 16 ? 0.21082 0.27374 0.17532 -0.00193 -0.02675 -0.01477 16  DG  C N1    
501  C C2    . DG  A 16 ? 0.24440 0.27238 0.20161 -0.00112 -0.02181 -0.01994 16  DG  C C2    
502  N N2    . DG  A 16 ? 0.25247 0.27094 0.20925 -0.00082 -0.01574 -0.02849 16  DG  C N2    
503  N N3    . DG  A 16 ? 0.26847 0.27025 0.20647 -0.00798 -0.01597 -0.01991 16  DG  C N3    
504  C C4    . DG  A 16 ? 0.24588 0.26323 0.19850 -0.02906 -0.02855 -0.00428 16  DG  C C4    
517  O "O5'" . DT  B 1  ? 0.31350 0.47120 0.94476 0.04736  0.08234  0.04701  17  DT  D "O5'" 
518  C "C5'" . DT  B 1  ? 0.29757 0.43401 0.82838 0.02485  -0.01990 0.04143  17  DT  D "C5'" 
519  C "C4'" . DT  B 1  ? 0.27440 0.37769 0.65040 0.00690  -0.09531 0.05428  17  DT  D "C4'" 
520  O "O4'" . DT  B 1  ? 0.28386 0.33636 0.50165 0.01332  -0.10737 0.03659  17  DT  D "O4'" 
521  C "C3'" . DT  B 1  ? 0.28373 0.32756 0.56824 -0.00196 -0.07090 0.08338  17  DT  D "C3'" 
522  O "O3'" . DT  B 1  ? 0.26791 0.29086 0.52329 -0.01302 -0.08772 0.09944  17  DT  D "O3'" 
523  C "C2'" . DT  B 1  ? 0.23989 0.31862 0.49785 0.00691  -0.07341 0.07026  17  DT  D "C2'" 
524  C "C1'" . DT  B 1  ? 0.25084 0.30912 0.44600 0.01386  -0.09192 0.05092  17  DT  D "C1'" 
525  N N1    . DT  B 1  ? 0.25577 0.29292 0.32480 0.03083  -0.05966 0.01513  17  DT  D N1    
526  C C2    . DT  B 1  ? 0.26831 0.29866 0.27137 0.03555  -0.05231 -0.01346 17  DT  D C2    
527  O O2    . DT  B 1  ? 0.30964 0.30257 0.28837 0.05197  -0.02607 0.01546  17  DT  D O2    
528  N N3    . DT  B 1  ? 0.24726 0.26869 0.26032 0.02689  -0.02826 -0.00790 17  DT  D N3    
529  C C4    . DT  B 1  ? 0.23238 0.28395 0.29548 0.03454  -0.05514 -0.00239 17  DT  D C4    
530  O O4    . DT  B 1  ? 0.27388 0.29327 0.29905 0.05592  -0.02932 0.01145  17  DT  D O4    
531  C C5    . DT  B 1  ? 0.25513 0.29802 0.36995 0.04450  -0.00204 0.04018  17  DT  D C5    
532  C C7    . DT  B 1  ? 0.25593 0.32607 0.42100 0.02902  0.03692  0.04701  17  DT  D C7    
533  C C6    . DT  B 1  ? 0.25697 0.30481 0.37229 0.03561  -0.03989 0.04495  17  DT  D C6    
547  P P     . DC  B 2  ? 0.28496 0.30030 0.45216 -0.04459 -0.03040 0.09988  18  DC  D P     
548  O OP1   . DC  B 2  ? 0.30094 0.28178 0.42487 -0.01126 -0.06196 0.11672  18  DC  D OP1   
549  O OP2   . DC  B 2  ? 0.34301 0.36442 0.50272 -0.03762 0.07636  0.12410  18  DC  D OP2   
550  O "O5'" . DC  B 2  ? 0.26734 0.28872 0.36330 -0.02613 -0.02349 0.07063  18  DC  D "O5'" 
551  C "C5'" . DC  B 2  ? 0.26366 0.27252 0.37210 -0.02080 0.00156  0.08049  18  DC  D "C5'" 
552  C "C4'" . DC  B 2  ? 0.26955 0.28285 0.33340 0.00832  -0.00368 0.08732  18  DC  D "C4'" 
553  O "O4'" . DC  B 2  ? 0.27217 0.24595 0.27970 -0.01099 -0.03066 0.03024  18  DC  D "O4'" 
554  C "C3'" . DC  B 2  ? 0.26678 0.31047 0.30116 0.01363  -0.05583 0.07656  18  DC  D "C3'" 
555  O "O3'" . DC  B 2  ? 0.25701 0.34366 0.35435 0.03518  -0.06623 0.10168  18  DC  D "O3'" 
556  C "C2'" . DC  B 2  ? 0.26490 0.29024 0.31852 -0.00097 -0.01024 0.06184  18  DC  D "C2'" 
557  C "C1'" . DC  B 2  ? 0.28183 0.26917 0.28213 -0.01272 0.01231  0.05208  18  DC  D "C1'" 
558  N N1    . DC  B 2  ? 0.26708 0.27835 0.23951 -0.00913 0.00676  0.03895  18  DC  D N1    
559  C C2    . DC  B 2  ? 0.25310 0.27182 0.20997 -0.00875 -0.01564 0.03747  18  DC  D C2    
560  O O2    . DC  B 2  ? 0.26956 0.25515 0.22948 0.00349  -0.00319 -0.00108 18  DC  D O2    
561  N N3    . DC  B 2  ? 0.23407 0.28058 0.21656 0.01465  -0.01762 0.03095  18  DC  D N3    
562  C C4    . DC  B 2  ? 0.24500 0.28659 0.22752 0.00115  -0.01092 0.02734  18  DC  D C4    
563  N N4    . DC  B 2  ? 0.25470 0.29552 0.23555 0.00434  -0.01609 0.01804  18  DC  D N4    
564  C C5    . DC  B 2  ? 0.27361 0.30004 0.24593 -0.00913 0.03401  0.03233  18  DC  D C5    
565  C C6    . DC  B 2  ? 0.31754 0.29810 0.27795 -0.00892 0.04058  0.02923  18  DC  D C6    
577  P P     . DC  B 3  ? 0.28623 0.36906 0.33885 -0.01330 -0.02687 0.06680  19  DC  D P     
578  O OP1   . DC  B 3  ? 0.29721 0.38454 0.35603 -0.01136 -0.04728 0.07799  19  DC  D OP1   
579  O OP2   . DC  B 3  ? 0.35456 0.41336 0.32671 0.01809  0.02964  0.06926  19  DC  D OP2   
580  O "O5'" . DC  B 3  ? 0.28916 0.35902 0.30368 -0.00797 -0.04520 0.08580  19  DC  D "O5'" 
581  C "C5'" . DC  B 3  ? 0.33457 0.33001 0.31909 -0.01448 -0.01010 0.05450  19  DC  D "C5'" 
582  C "C4'" . DC  B 3  ? 0.26309 0.31362 0.35893 0.01235  -0.02936 0.02322  19  DC  D "C4'" 
583  O "O4'" . DC  B 3  ? 0.25515 0.29105 0.33763 -0.01408 -0.02403 0.00866  19  DC  D "O4'" 
584  C "C3'" . DC  B 3  ? 0.30099 0.33593 0.37419 0.02373  -0.02574 0.01903  19  DC  D "C3'" 
585  O "O3'" . DC  B 3  ? 0.25310 0.35854 0.49176 -0.01186 -0.01399 -0.00352 19  DC  D "O3'" 
586  C "C2'" . DC  B 3  ? 0.27055 0.32550 0.36872 0.03926  -0.04652 0.02515  19  DC  D "C2'" 
587  C "C1'" . DC  B 3  ? 0.27826 0.29848 0.32451 -0.00576 -0.01011 0.02231  19  DC  D "C1'" 
588  N N1    . DC  B 3  ? 0.23010 0.31014 0.25909 -0.03434 -0.01782 -0.00069 19  DC  D N1    
589  C C2    . DC  B 3  ? 0.23491 0.33778 0.21627 -0.02362 -0.01512 0.00728  19  DC  D C2    
590  O O2    . DC  B 3  ? 0.25008 0.34283 0.22851 -0.02860 -0.00099 0.00390  19  DC  D O2    
591  N N3    . DC  B 3  ? 0.20679 0.34079 0.20299 -0.01703 -0.01539 0.00735  19  DC  D N3    
592  C C4    . DC  B 3  ? 0.22489 0.33011 0.20093 -0.01358 -0.02629 0.03565  19  DC  D C4    
593  N N4    . DC  B 3  ? 0.25474 0.33878 0.19740 -0.01521 -0.00696 0.03344  19  DC  D N4    
594  C C5    . DC  B 3  ? 0.23420 0.32154 0.18609 -0.01418 -0.00846 0.05747  19  DC  D C5    
595  C C6    . DC  B 3  ? 0.21158 0.30588 0.25407 -0.04136 -0.01728 -0.00124 19  DC  D C6    
607  P P     . DC  B 4  ? 0.28781 0.39959 0.54204 -0.00114 -0.06141 -0.00553 20  DC  D P     
608  O OP1   . DC  B 4  ? 0.32926 0.43971 0.68427 0.01228  0.03102  -0.02388 20  DC  D OP1   
609  O OP2   . DC  B 4  ? 0.34105 0.41407 0.50958 -0.01166 -0.09691 0.06653  20  DC  D OP2   
610  O "O5'" . DC  B 4  ? 0.35095 0.38542 0.42876 -0.03875 -0.01116 -0.05701 20  DC  D "O5'" 
611  C "C5'" . DC  B 4  ? 0.32832 0.39022 0.39860 -0.05311 0.03281  -0.07579 20  DC  D "C5'" 
612  C "C4'" . DC  B 4  ? 0.27600 0.39371 0.30129 -0.05742 0.03492  -0.09142 20  DC  D "C4'" 
613  O "O4'" . DC  B 4  ? 0.27982 0.39495 0.23305 -0.06688 0.00776  -0.06584 20  DC  D "O4'" 
614  C "C3'" . DC  B 4  ? 0.24308 0.40569 0.25846 -0.05328 0.00535  -0.09239 20  DC  D "C3'" 
615  O "O3'" . DC  B 4  ? 0.21456 0.43020 0.25824 -0.05475 0.01370  -0.12823 20  DC  D "O3'" 
616  C "C2'" . DC  B 4  ? 0.20579 0.39685 0.24524 -0.02484 -0.03554 -0.06623 20  DC  D "C2'" 
617  C "C1'" . DC  B 4  ? 0.24220 0.38048 0.21362 -0.04104 -0.01148 -0.07733 20  DC  D "C1'" 
618  N N1    . DC  B 4  ? 0.21671 0.37180 0.18633 -0.03089 -0.01112 -0.04800 20  DC  D N1    
619  C C2    . DC  B 4  ? 0.26794 0.36358 0.17134 -0.02756 -0.01107 -0.02960 20  DC  D C2    
620  O O2    . DC  B 4  ? 0.25710 0.37107 0.22499 -0.01413 -0.03121 -0.03435 20  DC  D O2    
621  N N3    . DC  B 4  ? 0.23398 0.34177 0.17403 -0.04157 -0.00601 -0.01385 20  DC  D N3    
622  C C4    . DC  B 4  ? 0.22504 0.33641 0.17056 -0.03881 -0.01361 -0.02985 20  DC  D C4    
623  N N4    . DC  B 4  ? 0.24182 0.32175 0.18761 -0.03686 0.00356  -0.04088 20  DC  D N4    
624  C C5    . DC  B 4  ? 0.25029 0.35850 0.15367 -0.04006 -0.01464 -0.04776 20  DC  D C5    
625  C C6    . DC  B 4  ? 0.23514 0.36377 0.19688 -0.05070 -0.00549 -0.01623 20  DC  D C6    
637  P P     . DA  B 5  ? 0.24354 0.44936 0.29027 -0.03957 0.02233  -0.13012 21  DA  D P     
638  O OP1   . DA  B 5  ? 0.32193 0.49372 0.33240 -0.07974 0.05343  -0.09695 21  DA  D OP1   
639  O OP2   . DA  B 5  ? 0.28803 0.44596 0.37253 0.00818  -0.02543 -0.11800 21  DA  D OP2   
640  O "O5'" . DA  B 5  ? 0.21419 0.39234 0.26551 -0.00661 -0.00131 -0.12597 21  DA  D "O5'" 
641  C "C5'" . DA  B 5  ? 0.20479 0.38098 0.19463 -0.03093 -0.01406 -0.08312 21  DA  D "C5'" 
642  C "C4'" . DA  B 5  ? 0.19643 0.35204 0.18512 -0.01866 -0.02476 -0.06831 21  DA  D "C4'" 
643  O "O4'" . DA  B 5  ? 0.19018 0.33522 0.15183 -0.01052 -0.02317 -0.03429 21  DA  D "O4'" 
644  C "C3'" . DA  B 5  ? 0.17782 0.32205 0.21641 -0.00670 -0.01742 -0.06048 21  DA  D "C3'" 
645  O "O3'" . DA  B 5  ? 0.18566 0.30995 0.19917 -0.00305 -0.01650 -0.03019 21  DA  D "O3'" 
646  C "C2'" . DA  B 5  ? 0.17902 0.30567 0.20886 -0.01268 0.00267  -0.05393 21  DA  D "C2'" 
647  C "C1'" . DA  B 5  ? 0.17079 0.31794 0.16751 -0.00326 -0.01699 -0.01949 21  DA  D "C1'" 
648  N N9    . DA  B 5  ? 0.18925 0.31250 0.17719 -0.00162 -0.02219 -0.01702 21  DA  D N9    
649  C C8    . DA  B 5  ? 0.20361 0.31860 0.17550 -0.00009 -0.01298 -0.04470 21  DA  D C8    
650  N N7    . DA  B 5  ? 0.17850 0.31433 0.20715 -0.00084 -0.02700 -0.05795 21  DA  D N7    
651  C C5    . DA  B 5  ? 0.18434 0.31227 0.18635 -0.01584 -0.02826 -0.04976 21  DA  D C5    
652  C C6    . DA  B 5  ? 0.19660 0.31774 0.17677 -0.01942 -0.04094 -0.04297 21  DA  D C6    
653  N N6    . DA  B 5  ? 0.20852 0.33301 0.19748 -0.05993 -0.01511 -0.03756 21  DA  D N6    
654  N N1    . DA  B 5  ? 0.20569 0.31276 0.16094 -0.00629 -0.01409 -0.01618 21  DA  D N1    
655  C C2    . DA  B 5  ? 0.21546 0.31520 0.15834 0.01080  -0.00119 -0.02045 21  DA  D C2    
656  N N3    . DA  B 5  ? 0.18233 0.29943 0.21863 0.00499  -0.01987 -0.03528 21  DA  D N3    
657  C C4    . DA  B 5  ? 0.17132 0.30844 0.15839 0.00297  -0.02593 -0.02833 21  DA  D C4    
669  P P     . DC  B 6  ? 0.18849 0.31818 0.18834 -0.01415 -0.00791 -0.01774 22  DC  D P     
670  O OP1   . DC  B 6  ? 0.17711 0.32766 0.17563 -0.02540 -0.01006 -0.01205 22  DC  D OP1   
671  O OP2   . DC  B 6  ? 0.18534 0.34569 0.19821 0.01465  -0.01071 -0.03256 22  DC  D OP2   
672  O "O5'" . DC  B 6  ? 0.19675 0.31192 0.18019 -0.02142 0.00086  -0.02032 22  DC  D "O5'" 
673  C "C5'" . DC  B 6  ? 0.18445 0.31295 0.17332 -0.03322 -0.01482 -0.03719 22  DC  D "C5'" 
674  C "C4'" . DC  B 6  ? 0.21167 0.31543 0.14516 -0.04023 -0.00811 -0.03376 22  DC  D "C4'" 
675  O "O4'" . DC  B 6  ? 0.17453 0.31468 0.17729 -0.01962 -0.00893 -0.02611 22  DC  D "O4'" 
676  C "C3'" . DC  B 6  ? 0.22218 0.30676 0.15840 0.00880  -0.02000 -0.00964 22  DC  D "C3'" 
677  O "O3'" . DC  B 6  ? 0.19633 0.30043 0.16991 -0.00668 0.00718  -0.02300 22  DC  D "O3'" 
678  C "C2'" . DC  B 6  ? 0.24941 0.31740 0.17028 -0.00847 0.02149  -0.02941 22  DC  D "C2'" 
679  C "C1'" . DC  B 6  ? 0.21109 0.31311 0.16416 -0.01375 -0.00759 -0.02978 22  DC  D "C1'" 
680  N N1    . DC  B 6  ? 0.18161 0.29871 0.16151 0.01290  0.01032  -0.04099 22  DC  D N1    
681  C C2    . DC  B 6  ? 0.16192 0.29602 0.18764 -0.00540 -0.02617 -0.03282 22  DC  D C2    
682  O O2    . DC  B 6  ? 0.19972 0.29610 0.18592 0.00939  -0.00275 -0.03903 22  DC  D O2    
683  N N3    . DC  B 6  ? 0.17778 0.27291 0.17788 0.00260  -0.02092 -0.02900 22  DC  D N3    
684  C C4    . DC  B 6  ? 0.15615 0.28902 0.19905 -0.00816 -0.03670 -0.02948 22  DC  D C4    
685  N N4    . DC  B 6  ? 0.18362 0.29690 0.22222 0.00794  -0.02591 -0.03207 22  DC  D N4    
686  C C5    . DC  B 6  ? 0.17812 0.30529 0.18455 -0.00608 -0.03381 -0.01099 22  DC  D C5    
687  C C6    . DC  B 6  ? 0.16854 0.29886 0.20179 0.00499  -0.00155 -0.04875 22  DC  D C6    
699  P P     . DT  B 7  ? 0.19845 0.29778 0.17159 -0.01017 0.00580  -0.01740 23  DT  D P     
700  O OP1   . DT  B 7  ? 0.20986 0.28756 0.18356 -0.01905 0.00205  -0.01030 23  DT  D OP1   
701  O OP2   . DT  B 7  ? 0.18256 0.29873 0.19161 -0.00519 -0.02062 -0.01081 23  DT  D OP2   
702  O "O5'" . DT  B 7  ? 0.16931 0.30404 0.16523 -0.01161 -0.00409 -0.00863 23  DT  D "O5'" 
703  C "C5'" . DT  B 7  ? 0.18695 0.30805 0.20006 -0.03184 0.00125  -0.01077 23  DT  D "C5'" 
704  C "C4'" . DT  B 7  ? 0.19746 0.31544 0.16664 -0.02154 -0.01785 0.00509  23  DT  D "C4'" 
705  O "O4'" . DT  B 7  ? 0.18697 0.31930 0.16637 -0.01594 -0.03107 0.00359  23  DT  D "O4'" 
706  C "C3'" . DT  B 7  ? 0.18092 0.32546 0.17234 -0.00163 -0.00800 -0.01109 23  DT  D "C3'" 
707  O "O3'" . DT  B 7  ? 0.19191 0.31851 0.20125 0.02538  0.01309  -0.00523 23  DT  D "O3'" 
708  C "C2'" . DT  B 7  ? 0.16141 0.32556 0.19745 -0.01923 -0.02353 -0.00203 23  DT  D "C2'" 
709  C "C1'" . DT  B 7  ? 0.18308 0.32217 0.12320 0.01953  -0.01438 0.02496  23  DT  D "C1'" 
710  N N1    . DT  B 7  ? 0.18062 0.30293 0.16980 0.00891  -0.02471 -0.00008 23  DT  D N1    
711  C C2    . DT  B 7  ? 0.16963 0.31350 0.18138 -0.00237 -0.04525 0.00741  23  DT  D C2    
712  O O2    . DT  B 7  ? 0.18397 0.34784 0.17113 -0.00262 -0.02574 -0.00195 23  DT  D O2    
713  N N3    . DT  B 7  ? 0.18138 0.29587 0.19832 0.01676  -0.02047 0.00939  23  DT  D N3    
714  C C4    . DT  B 7  ? 0.20234 0.29644 0.14057 0.02169  -0.03628 0.03197  23  DT  D C4    
715  O O4    . DT  B 7  ? 0.22513 0.29061 0.20862 0.01530  -0.02392 0.00182  23  DT  D O4    
716  C C5    . DT  B 7  ? 0.19249 0.31116 0.16098 0.02705  -0.01643 0.00572  23  DT  D C5    
717  C C7    . DT  B 7  ? 0.19664 0.31742 0.19895 0.02460  -0.00410 0.01269  23  DT  D C7    
718  C C6    . DT  B 7  ? 0.18012 0.29277 0.17613 -0.00563 -0.02064 -0.00470 23  DT  D C6    
731  P P     . DT  B 8  ? 0.21640 0.31706 0.21500 0.02575  0.01599  -0.00554 24  DT  D P     
732  O OP1   . DT  B 8  ? 0.23135 0.33064 0.26727 0.04580  0.03251  -0.00208 24  DT  D OP1   
733  O OP2   . DT  B 8  ? 0.18739 0.32634 0.24373 -0.00169 0.01119  -0.02875 24  DT  D OP2   
734  O "O5'" . DT  B 8  ? 0.16167 0.31528 0.23502 0.02074  -0.00977 0.00242  24  DT  D "O5'" 
735  C "C5'" . DT  B 8  ? 0.17415 0.32555 0.22639 0.03241  0.00555  0.02379  24  DT  D "C5'" 
736  C "C4'" . DT  B 8  ? 0.19813 0.32164 0.22515 0.03631  0.03011  0.01243  24  DT  D "C4'" 
737  O "O4'" . DT  B 8  ? 0.20541 0.31046 0.19045 0.03707  0.00877  0.00905  24  DT  D "O4'" 
738  C "C3'" . DT  B 8  ? 0.24189 0.32590 0.23832 0.06054  0.03353  0.02150  24  DT  D "C3'" 
739  O "O3'" . DT  B 8  ? 0.26723 0.34890 0.28330 0.04387  0.06581  0.00024  24  DT  D "O3'" 
740  C "C2'" . DT  B 8  ? 0.31015 0.33957 0.21905 0.06097  0.03706  0.02011  24  DT  D "C2'" 
741  C "C1'" . DT  B 8  ? 0.25595 0.31347 0.19671 0.04361  0.02644  0.00888  24  DT  D "C1'" 
742  N N1    . DT  B 8  ? 0.23153 0.30689 0.16161 0.05386  0.00020  -0.00012 24  DT  D N1    
743  C C2    . DT  B 8  ? 0.22847 0.32659 0.19401 0.02822  -0.02608 -0.02495 24  DT  D C2    
744  O O2    . DT  B 8  ? 0.23918 0.32506 0.26286 0.02307  -0.00766 0.00412  24  DT  D O2    
745  N N3    . DT  B 8  ? 0.24556 0.32855 0.17092 0.04024  -0.04512 -0.01289 24  DT  D N3    
746  C C4    . DT  B 8  ? 0.24665 0.34042 0.18557 0.03279  -0.08665 -0.01631 24  DT  D C4    
747  O O4    . DT  B 8  ? 0.25973 0.33901 0.16821 0.05379  -0.06921 -0.02609 24  DT  D O4    
748  C C5    . DT  B 8  ? 0.19994 0.32506 0.15547 0.04931  -0.05596 -0.02812 24  DT  D C5    
749  C C7    . DT  B 8  ? 0.19852 0.34191 0.19233 0.04799  -0.05648 -0.00596 24  DT  D C7    
750  C C6    . DT  B 8  ? 0.21478 0.31904 0.17185 0.05599  -0.02997 -0.02369 24  DT  D C6    
763  P P     . DT  B 9  ? 0.34350 0.39712 0.28736 0.05233  0.07881  -0.02759 25  DT  D P     
764  O OP1   . DT  B 9  ? 0.33706 0.40905 0.38939 0.07684  0.10019  -0.04779 25  DT  D OP1   
765  O OP2   . DT  B 9  ? 0.28134 0.41450 0.26113 0.06080  0.05292  -0.04669 25  DT  D OP2   
766  O "O5'" . DT  B 9  ? 0.41850 0.42717 0.27263 0.00050  0.11979  -0.00786 25  DT  D "O5'" 
767  C "C5'" . DT  B 9  ? 0.54392 0.45499 0.32293 0.02844  0.17252  0.01372  25  DT  D "C5'" 
768  C "C4'" . DT  B 9  ? 0.62669 0.49047 0.32347 0.04849  0.18228  0.03136  25  DT  D "C4'" 
769  O "O4'" . DT  B 9  ? 0.55302 0.47790 0.29123 0.06772  0.11802  0.04479  25  DT  D "O4'" 
770  C "C3'" . DT  B 9  ? 0.74880 0.53221 0.35770 0.05189  0.25023  0.06592  25  DT  D "C3'" 
771  O "O3'" . DT  B 9  ? 0.90874 0.61302 0.43739 0.03619  0.30751  0.10265  25  DT  D "O3'" 
772  C "C2'" . DT  B 9  ? 0.66123 0.50159 0.31595 0.07689  0.17500  0.04805  25  DT  D "C2'" 
773  C "C1'" . DT  B 9  ? 0.54313 0.47192 0.25971 0.07742  0.12979  0.05818  25  DT  D "C1'" 
774  N N1    . DT  B 9  ? 0.44939 0.44454 0.21666 0.06374  0.08619  0.03965  25  DT  D N1    
775  C C2    . DT  B 9  ? 0.35628 0.45447 0.24546 0.03775  0.00478  0.01600  25  DT  D C2    
776  O O2    . DT  B 9  ? 0.38351 0.47062 0.34401 0.01546  0.03259  0.01931  25  DT  D O2    
777  N N3    . DT  B 9  ? 0.22791 0.43144 0.16800 0.01972  -0.01453 0.00779  25  DT  D N3    
778  C C4    . DT  B 9  ? 0.28390 0.41586 0.16995 0.00631  -0.00819 0.00496  25  DT  D C4    
779  O O4    . DT  B 9  ? 0.26278 0.39618 0.15246 0.03589  -0.00564 0.01592  25  DT  D O4    
780  C C5    . DT  B 9  ? 0.31214 0.42008 0.15127 0.03085  0.05361  -0.00530 25  DT  D C5    
781  C C7    . DT  B 9  ? 0.30670 0.42801 0.22738 0.00366  -0.00407 -0.03836 25  DT  D C7    
782  C C6    . DT  B 9  ? 0.46031 0.44312 0.15275 0.00850  0.10034  -0.00333 25  DT  D C6    
795  P P     . DC  B 10 ? 0.92668 0.68264 0.44481 0.03753  0.30366  0.12846  26  DC  D P     
796  O OP1   . DC  B 10 ? 1.00934 0.69700 0.48751 0.04548  0.31340  0.16454  26  DC  D OP1   
797  O OP2   . DC  B 10 ? 0.97521 0.69811 0.41654 0.02347  0.27116  0.13398  26  DC  D OP2   
798  O "O5'" . DC  B 10 ? 0.97597 0.71864 0.47606 0.00499  0.27361  0.13035  26  DC  D "O5'" 
799  C "C5'" . DC  B 10 ? 0.96901 0.75083 0.48963 -0.02436 0.21838  0.13142  26  DC  D "C5'" 
800  C "C4'" . DC  B 10 ? 0.96199 0.77624 0.48174 -0.05421 0.12878  0.13697  26  DC  D "C4'" 
801  O "O4'" . DC  B 10 ? 0.92535 0.76744 0.48599 -0.07729 0.07028  0.13977  26  DC  D "O4'" 
802  C "C3'" . DC  B 10 ? 0.97566 0.79959 0.45594 -0.06762 0.09097  0.12491  26  DC  D "C3'" 
803  O "O3'" . DC  B 10 ? 1.03918 0.82370 0.40670 -0.07870 0.14904  0.12111  26  DC  D "O3'" 
804  C "C2'" . DC  B 10 ? 0.93715 0.78498 0.47611 -0.07638 0.03033  0.12512  26  DC  D "C2'" 
805  C "C1'" . DC  B 10 ? 0.90786 0.76185 0.48323 -0.08531 0.00184  0.12497  26  DC  D "C1'" 
806  N N1    . DC  B 10 ? 0.87031 0.73071 0.45084 -0.10346 -0.09919 0.09794  26  DC  D N1    
807  C C2    . DC  B 10 ? 0.83819 0.70336 0.35656 -0.11311 -0.20179 0.10573  26  DC  D C2    
808  O O2    . DC  B 10 ? 0.82949 0.69291 0.33310 -0.12687 -0.20105 0.12546  26  DC  D O2    
809  N N3    . DC  B 10 ? 0.80413 0.67981 0.34989 -0.13159 -0.24252 0.05943  26  DC  D N3    
810  C C4    . DC  B 10 ? 0.80074 0.67439 0.38378 -0.13730 -0.19436 0.04666  26  DC  D C4    
811  N N4    . DC  B 10 ? 0.73195 0.63270 0.34789 -0.16478 -0.22319 -0.01318 26  DC  D N4    
812  C C5    . DC  B 10 ? 0.82955 0.69270 0.46178 -0.13771 -0.14611 0.04917  26  DC  D C5    
813  C C6    . DC  B 10 ? 0.84804 0.71348 0.48765 -0.11967 -0.12895 0.06638  26  DC  D C6    
825  P P     . DG  B 11 ? 1.07315 0.84548 0.39701 -0.09380 0.20215  0.15764  27  DG  D P     
826  O OP1   . DG  B 11 ? 1.10293 0.85116 0.45476 -0.09360 0.20209  0.11791  27  DG  D OP1   
827  O OP2   . DG  B 11 ? 1.15559 0.84948 0.43905 -0.09583 0.25796  0.13105  27  DG  D OP2   
828  O "O5'" . DG  B 11 ? 0.93762 0.89682 0.43239 -0.07555 0.16063  0.14197  27  DG  D "O5'" 
829  C "C5'" . DG  B 11 ? 0.79748 0.94170 0.43417 -0.04245 0.10829  0.16390  27  DG  D "C5'" 
830  C "C4'" . DG  B 11 ? 0.62911 0.98148 0.40761 -0.01759 0.03148  0.19487  27  DG  D "C4'" 
831  O "O4'" . DG  B 11 ? 0.53718 0.98581 0.37666 -0.00976 -0.00971 0.17976  27  DG  D "O4'" 
832  C "C3'" . DG  B 11 ? 0.55343 1.01242 0.40495 0.01059  0.00690  0.22364  27  DG  D "C3'" 
833  O "O3'" . DG  B 11 ? 0.54646 1.05342 0.42861 0.05864  -0.01503 0.26919  27  DG  D "O3'" 
834  C "C2'" . DG  B 11 ? 0.49783 0.99499 0.34549 -0.00824 -0.06981 0.19070  27  DG  D "C2'" 
835  C "C1'" . DG  B 11 ? 0.48200 0.97169 0.31810 -0.01186 -0.02909 0.17314  27  DG  D "C1'" 
836  N N9    . DG  B 11 ? 0.39266 0.92044 0.35700 -0.02111 -0.03503 0.11896  27  DG  D N9    
837  C C8    . DG  B 11 ? 0.39388 0.90477 0.39643 -0.01471 -0.01831 0.09747  27  DG  D C8    
838  N N7    . DG  B 11 ? 0.37935 0.88361 0.36063 -0.00192 0.00761  0.08970  27  DG  D N7    
839  C C5    . DG  B 11 ? 0.37506 0.86467 0.26900 0.00525  -0.04542 0.07933  27  DG  D C5    
840  C C6    . DG  B 11 ? 0.38820 0.80419 0.22778 0.02287  -0.06059 0.05091  27  DG  D C6    
841  O O6    . DG  B 11 ? 0.40052 0.79188 0.23406 0.03068  -0.08251 0.01908  27  DG  D O6    
842  N N1    . DG  B 11 ? 0.32756 0.79060 0.26323 0.05812  -0.05875 0.10523  27  DG  D N1    
843  C C2    . DG  B 11 ? 0.32315 0.84468 0.27379 0.03722  -0.04674 0.12882  27  DG  D C2    
844  N N2    . DG  B 11 ? 0.28143 0.84660 0.39116 0.02868  -0.02989 0.17950  27  DG  D N2    
845  N N3    . DG  B 11 ? 0.32003 0.86167 0.27757 0.00076  -0.06342 0.10490  27  DG  D N3    
846  C C4    . DG  B 11 ? 0.37079 0.88444 0.29454 0.00203  -0.06663 0.09812  27  DG  D C4    
858  P P     . DC  B 12 ? 0.55176 1.07449 0.49736 0.07526  0.02076  0.28847  28  DC  D P     
859  O OP1   . DC  B 12 ? 0.57310 1.09279 0.56362 0.10564  0.05933  0.32808  28  DC  D OP1   
860  O OP2   . DC  B 12 ? 0.61055 1.10366 0.48828 0.07714  0.03573  0.29617  28  DC  D OP2   
861  O "O5'" . DC  B 12 ? 0.47848 1.01486 0.48342 0.01632  -0.03982 0.22231  28  DC  D "O5'" 
862  C "C5'" . DC  B 12 ? 0.39478 0.93196 0.46118 -0.01474 -0.06050 0.19898  28  DC  D "C5'" 
863  C "C4'" . DC  B 12 ? 0.37815 0.83198 0.41588 -0.05516 -0.10233 0.17865  28  DC  D "C4'" 
864  O "O4'" . DC  B 12 ? 0.35114 0.78411 0.36902 -0.07437 -0.11833 0.15895  28  DC  D "O4'" 
865  C "C3'" . DC  B 12 ? 0.37845 0.77307 0.40987 -0.07476 -0.12897 0.20855  28  DC  D "C3'" 
866  O "O3'" . DC  B 12 ? 0.41293 0.72570 0.48206 -0.08927 -0.12872 0.25493  28  DC  D "O3'" 
867  C "C2'" . DC  B 12 ? 0.36782 0.76265 0.39324 -0.07644 -0.11092 0.17804  28  DC  D "C2'" 
868  C "C1'" . DC  B 12 ? 0.34495 0.75122 0.34993 -0.08123 -0.10126 0.12114  28  DC  D "C1'" 
869  N N1    . DC  B 12 ? 0.31070 0.71028 0.29605 -0.05251 -0.06072 0.09040  28  DC  D N1    
870  C C2    . DC  B 12 ? 0.26488 0.68678 0.22798 -0.04233 -0.05706 0.06963  28  DC  D C2    
871  O O2    . DC  B 12 ? 0.28149 0.66815 0.30898 -0.07284 -0.03516 0.08519  28  DC  D O2    
872  N N3    . DC  B 12 ? 0.29116 0.67317 0.19847 -0.01663 -0.03234 0.06089  28  DC  D N3    
873  C C4    . DC  B 12 ? 0.32528 0.66906 0.21337 -0.01205 -0.01602 0.07148  28  DC  D C4    
874  N N4    . DC  B 12 ? 0.33335 0.64577 0.20917 0.00139  -0.06021 0.08435  28  DC  D N4    
875  C C5    . DC  B 12 ? 0.30034 0.68627 0.25679 -0.03053 -0.03008 0.04120  28  DC  D C5    
876  C C6    . DC  B 12 ? 0.28396 0.69784 0.26333 -0.03439 -0.06832 0.07573  28  DC  D C6    
888  P P     . DT  B 13 ? 0.48873 0.69447 0.55238 -0.08924 -0.09536 0.26973  29  DT  D P     
889  O OP1   . DT  B 13 ? 0.50084 0.69341 0.59752 -0.10695 -0.12447 0.26504  29  DT  D OP1   
890  O OP2   . DT  B 13 ? 0.55631 0.72702 0.57527 -0.05294 -0.03056 0.25608  29  DT  D OP2   
891  O "O5'" . DT  B 13 ? 0.48150 0.61922 0.51668 -0.13685 -0.14488 0.19669  29  DT  D "O5'" 
892  C "C5'" . DT  B 13 ? 0.48980 0.54899 0.45854 -0.13140 -0.17621 0.15087  29  DT  D "C5'" 
893  C "C4'" . DT  B 13 ? 0.50304 0.48209 0.40083 -0.12056 -0.17472 0.11744  29  DT  D "C4'" 
894  O "O4'" . DT  B 13 ? 0.50404 0.46986 0.33387 -0.10546 -0.19152 0.09203  29  DT  D "O4'" 
895  C "C3'" . DT  B 13 ? 0.48840 0.43903 0.37937 -0.10721 -0.17964 0.09518  29  DT  D "C3'" 
896  O "O3'" . DT  B 13 ? 0.50588 0.39813 0.42564 -0.10773 -0.17532 0.08482  29  DT  D "O3'" 
897  C "C2'" . DT  B 13 ? 0.47024 0.44068 0.33766 -0.08559 -0.17225 0.12528  29  DT  D "C2'" 
898  C "C1'" . DT  B 13 ? 0.44680 0.45243 0.31233 -0.09153 -0.17393 0.09570  29  DT  D "C1'" 
899  N N1    . DT  B 13 ? 0.37924 0.44170 0.29991 -0.05056 -0.13493 0.09327  29  DT  D N1    
900  C C2    . DT  B 13 ? 0.37112 0.41552 0.29812 -0.04290 -0.08636 0.08233  29  DT  D C2    
901  O O2    . DT  B 13 ? 0.36747 0.38123 0.32892 -0.03360 -0.08426 0.07812  29  DT  D O2    
902  N N3    . DT  B 13 ? 0.33493 0.43851 0.26248 -0.02921 -0.09284 0.07583  29  DT  D N3    
903  C C4    . DT  B 13 ? 0.33056 0.46222 0.26080 -0.02863 -0.10032 0.05024  29  DT  D C4    
904  O O4    . DT  B 13 ? 0.35097 0.47595 0.22565 -0.01460 -0.10780 0.03724  29  DT  D O4    
905  C C5    . DT  B 13 ? 0.33319 0.47415 0.28869 -0.04419 -0.12637 0.05135  29  DT  D C5    
906  C C7    . DT  B 13 ? 0.34432 0.49709 0.32870 -0.02865 -0.07654 0.05064  29  DT  D C7    
907  C C6    . DT  B 13 ? 0.34510 0.46257 0.30363 -0.04635 -0.11632 0.08194  29  DT  D C6    
920  P P     . DT  B 14 ? 0.53159 0.36935 0.40447 -0.08705 -0.09726 0.07256  30  DT  D P     
921  O OP1   . DT  B 14 ? 0.58303 0.37535 0.45177 -0.09300 -0.08298 0.05410  30  DT  D OP1   
922  O OP2   . DT  B 14 ? 0.53693 0.38582 0.35144 -0.05630 -0.01655 0.11639  30  DT  D OP2   
923  O "O5'" . DT  B 14 ? 0.52112 0.35331 0.40110 -0.04949 -0.09185 0.04570  30  DT  D "O5'" 
924  C "C5'" . DT  B 14 ? 0.47715 0.34268 0.37766 -0.03194 -0.15197 0.01372  30  DT  D "C5'" 
925  C "C4'" . DT  B 14 ? 0.45702 0.32418 0.34646 0.00311  -0.11375 -0.02294 30  DT  D "C4'" 
926  O "O4'" . DT  B 14 ? 0.42691 0.32613 0.33562 0.01155  -0.10392 -0.01271 30  DT  D "O4'" 
927  C "C3'" . DT  B 14 ? 0.43512 0.33224 0.33334 0.01671  -0.09141 -0.06651 30  DT  D "C3'" 
928  O "O3'" . DT  B 14 ? 0.42903 0.36021 0.34810 0.03847  -0.09492 -0.05840 30  DT  D "O3'" 
929  C "C2'" . DT  B 14 ? 0.42352 0.31712 0.30031 0.04966  -0.11191 -0.02420 30  DT  D "C2'" 
930  C "C1'" . DT  B 14 ? 0.41003 0.32324 0.29968 0.01766  -0.11950 -0.00080 30  DT  D "C1'" 
931  N N1    . DT  B 14 ? 0.41349 0.34349 0.26791 0.00328  -0.10332 0.02815  30  DT  D N1    
932  C C2    . DT  B 14 ? 0.43415 0.35062 0.25897 -0.01466 -0.07705 0.01126  30  DT  D C2    
933  O O2    . DT  B 14 ? 0.42844 0.34153 0.25165 -0.01997 -0.11243 0.02458  30  DT  D O2    
934  N N3    . DT  B 14 ? 0.42434 0.36396 0.21405 -0.02296 -0.12925 0.01658  30  DT  D N3    
935  C C4    . DT  B 14 ? 0.45447 0.39451 0.23777 -0.05237 -0.10258 0.00024  30  DT  D C4    
936  O O4    . DT  B 14 ? 0.43839 0.42289 0.24967 -0.04719 -0.14055 -0.00727 30  DT  D O4    
937  C C5    . DT  B 14 ? 0.43783 0.38771 0.26160 -0.06205 -0.14293 0.01672  30  DT  D C5    
938  C C7    . DT  B 14 ? 0.48972 0.42160 0.27114 -0.04520 -0.14013 0.04325  30  DT  D C7    
939  C C6    . DT  B 14 ? 0.43708 0.35964 0.25000 -0.04045 -0.11825 0.03649  30  DT  D C6    
952  P P     . DA  B 15 ? 0.41130 0.36338 0.33700 0.04474  -0.04549 -0.04680 31  DA  D P     
953  O OP1   . DA  B 15 ? 0.46834 0.39341 0.39917 0.06815  -0.03228 -0.06187 31  DA  D OP1   
954  O OP2   . DA  B 15 ? 0.47846 0.36650 0.23210 0.00006  0.00217  0.01160  31  DA  D OP2   
955  O "O5'" . DA  B 15 ? 0.38022 0.34255 0.31395 0.03483  -0.03563 -0.04945 31  DA  D "O5'" 
956  C "C5'" . DA  B 15 ? 0.41013 0.34424 0.34176 0.05422  -0.02496 -0.01954 31  DA  D "C5'" 
957  C "C4'" . DA  B 15 ? 0.35087 0.34263 0.27588 0.04490  -0.03348 -0.01648 31  DA  D "C4'" 
958  O "O4'" . DA  B 15 ? 0.34151 0.32741 0.26543 0.04667  -0.00631 -0.04958 31  DA  D "O4'" 
959  C "C3'" . DA  B 15 ? 0.33717 0.35519 0.30219 0.02895  -0.01237 -0.02143 31  DA  D "C3'" 
960  O "O3'" . DA  B 15 ? 0.33968 0.42385 0.44295 -0.00331 0.05157  -0.03704 31  DA  D "O3'" 
961  C "C2'" . DA  B 15 ? 0.30840 0.32052 0.28380 0.01114  0.00524  -0.03380 31  DA  D "C2'" 
962  C "C1'" . DA  B 15 ? 0.32040 0.30088 0.23176 0.02028  -0.02440 -0.04672 31  DA  D "C1'" 
963  N N9    . DA  B 15 ? 0.29762 0.29460 0.23196 0.00922  -0.03954 -0.04040 31  DA  D N9    
964  C C8    . DA  B 15 ? 0.29556 0.29039 0.22593 0.01499  -0.03787 -0.01423 31  DA  D C8    
965  N N7    . DA  B 15 ? 0.29283 0.28660 0.19259 0.02177  -0.05811 -0.01601 31  DA  D N7    
966  C C5    . DA  B 15 ? 0.32056 0.28000 0.17897 0.02490  -0.05674 -0.03612 31  DA  D C5    
967  C C6    . DA  B 15 ? 0.34048 0.28910 0.14974 0.02772  -0.07203 0.00082  31  DA  D C6    
968  N N6    . DA  B 15 ? 0.35375 0.28870 0.18506 0.04373  -0.04359 -0.02331 31  DA  D N6    
969  N N1    . DA  B 15 ? 0.37366 0.29464 0.19404 0.04406  -0.04578 -0.00181 31  DA  D N1    
970  C C2    . DA  B 15 ? 0.37901 0.29952 0.18876 0.03737  -0.03169 -0.00640 31  DA  D C2    
971  N N3    . DA  B 15 ? 0.37003 0.30256 0.20208 0.04103  -0.02638 -0.02900 31  DA  D N3    
972  C C4    . DA  B 15 ? 0.31529 0.28143 0.21395 0.02811  -0.04320 -0.02436 31  DA  D C4    
984  P P     . DT  B 16 ? 0.44158 0.48156 0.55603 -0.01205 0.10169  -0.06889 32  DT  D P     
985  O OP1   . DT  B 16 ? 0.51982 0.47011 0.61537 0.03045  0.18220  -0.10539 32  DT  D OP1   
986  O OP2   . DT  B 16 ? 0.48839 0.54478 0.61385 -0.00651 0.04529  -0.00287 32  DT  D OP2   
987  O "O5'" . DT  B 16 ? 0.47227 0.51052 0.64394 0.01498  0.14961  -0.03064 32  DT  D "O5'" 
988  N N     . LYS C 5  ? 0.47369 0.65281 0.63840 0.05990  -0.13201 0.03428  169 LYS F N     
989  C CA    . LYS C 5  ? 0.42939 0.64810 0.60148 0.06497  -0.13932 0.07127  169 LYS F CA    
990  C C     . LYS C 5  ? 0.45426 0.62710 0.42562 0.04169  -0.08872 0.08132  169 LYS F C     
991  O O     . LYS C 5  ? 0.48290 0.64141 0.33566 0.02014  -0.08946 0.06471  169 LYS F O     
992  C CB    . LYS C 5  ? 0.39677 0.65273 0.72726 0.08758  -0.13391 0.07026  169 LYS F CB    
994  N N     . ILE C 6  ? 0.46078 0.59495 0.33495 0.03141  -0.02370 0.09712  170 ILE F N     
995  C CA    . ILE C 6  ? 0.43309 0.54998 0.33039 0.02019  -0.02323 0.12391  170 ILE F CA    
996  C C     . ILE C 6  ? 0.30210 0.50168 0.23273 0.00114  0.00844  0.06891  170 ILE F C     
997  O O     . ILE C 6  ? 0.33051 0.51962 0.24216 0.08514  0.03706  0.05314  170 ILE F O     
998  C CB    . ILE C 6  ? 0.57016 0.57265 0.42566 0.00404  0.02678  0.15466  170 ILE F CB    
999  C CG1   . ILE C 6  ? 0.60773 0.59844 0.44113 0.00004  -0.02517 0.16085  170 ILE F CG1   
1000 C CG2   . ILE C 6  ? 0.64301 0.57717 0.48028 -0.00800 0.12368  0.17882  170 ILE F CG2   
1001 C CD1   . ILE C 6  ? 0.64968 0.61487 0.47618 0.00283  0.00439  0.15327  170 ILE F CD1   
1013 N N     . ARG C 7  ? 0.24376 0.44161 0.18950 -0.02641 -0.01260 0.00806  171 ARG F N     
1014 C CA    . ARG C 7  ? 0.22274 0.40056 0.17443 0.01161  -0.00305 0.01081  171 ARG F CA    
1015 C C     . ARG C 7  ? 0.19699 0.34241 0.17910 0.00363  0.00432  0.00435  171 ARG F C     
1016 O O     . ARG C 7  ? 0.20306 0.34356 0.18868 -0.00734 -0.00114 0.01806  171 ARG F O     
1017 C CB    . ARG C 7  ? 0.26353 0.43619 0.16700 0.03291  -0.03549 -0.01065 171 ARG F CB    
1018 C CG    . ARG C 7  ? 0.35703 0.50130 0.19921 0.04199  -0.01483 -0.07592 171 ARG F CG    
1019 C CD    . ARG C 7  ? 0.36086 0.55962 0.28329 -0.00106 0.01816  -0.11126 171 ARG F CD    
1020 N NE    . ARG C 7  ? 0.24194 0.60281 0.33834 -0.07258 0.04336  -0.14333 171 ARG F NE    
1021 C CZ    . ARG C 7  ? 0.24075 0.64013 0.37104 -0.06984 0.01690  -0.17460 171 ARG F CZ    
1022 N NH1   . ARG C 7  ? 0.35689 0.65650 0.41555 -0.09908 0.06931  -0.21561 171 ARG F NH1   
1023 N NH2   . ARG C 7  ? 0.23906 0.65225 0.41844 -0.04869 -0.01068 -0.16722 171 ARG F NH2   
1037 N N     . LEU C 8  ? 0.18506 0.30892 0.17945 -0.01397 0.00318  -0.00315 172 LEU F N     
1038 C CA    . LEU C 8  ? 0.18783 0.27516 0.18591 -0.01313 -0.01449 0.01599  172 LEU F CA    
1039 C C     . LEU C 8  ? 0.18839 0.27930 0.17872 -0.00156 0.00046  0.01529  172 LEU F C     
1040 O O     . LEU C 8  ? 0.19341 0.27442 0.18298 -0.01611 -0.00613 -0.01399 172 LEU F O     
1041 C CB    . LEU C 8  ? 0.20002 0.25295 0.17518 -0.01901 -0.00941 0.00927  172 LEU F CB    
1042 C CG    . LEU C 8  ? 0.21483 0.23100 0.16769 -0.01424 -0.00749 -0.00703 172 LEU F CG    
1043 C CD1   . LEU C 8  ? 0.18890 0.23654 0.22566 -0.00069 -0.01455 0.01346  172 LEU F CD1   
1044 C CD2   . LEU C 8  ? 0.26465 0.22296 0.18628 -0.02016 0.04282  0.00901  172 LEU F CD2   
1056 N N     . TYR C 9  ? 0.19898 0.27550 0.19591 -0.01071 -0.02023 -0.02261 173 TYR F N     
1057 C CA    . TYR C 9  ? 0.18935 0.28662 0.20287 0.02156  -0.00027 -0.00296 173 TYR F CA    
1058 C C     . TYR C 9  ? 0.18975 0.30283 0.15646 -0.00299 -0.02264 -0.00637 173 TYR F C     
1059 O O     . TYR C 9  ? 0.18234 0.31229 0.20524 -0.01709 -0.00909 -0.00712 173 TYR F O     
1060 C CB    . TYR C 9  ? 0.20782 0.32811 0.22964 0.01410  0.00002  -0.03433 173 TYR F CB    
1061 C CG    . TYR C 9  ? 0.23126 0.33899 0.22291 -0.01669 -0.00506 -0.05559 173 TYR F CG    
1062 C CD1   . TYR C 9  ? 0.27787 0.35073 0.22748 -0.00538 0.02396  -0.03002 173 TYR F CD1   
1063 C CD2   . TYR C 9  ? 0.22447 0.36859 0.25558 -0.04494 0.01572  -0.08728 173 TYR F CD2   
1064 C CE1   . TYR C 9  ? 0.35061 0.39385 0.23932 -0.00987 0.03429  -0.07982 173 TYR F CE1   
1065 C CE2   . TYR C 9  ? 0.25671 0.40308 0.27680 0.00006  -0.02856 -0.07686 173 TYR F CE2   
1066 C CZ    . TYR C 9  ? 0.36165 0.42175 0.20896 0.00881  -0.02591 -0.08271 173 TYR F CZ    
1067 O OH    . TYR C 9  ? 0.49496 0.47434 0.21840 0.00254  -0.00725 -0.10361 173 TYR F OH    
1077 N N     . GLN C 10 ? 0.22270 0.34376 0.17275 0.00653  -0.02047 -0.00946 174 GLN F N     
1078 C CA    . GLN C 10 ? 0.22449 0.37813 0.17080 0.00262  0.00248  0.02728  174 GLN F CA    
1079 C C     . GLN C 10 ? 0.21567 0.36188 0.19073 -0.00532 -0.00346 0.03664  174 GLN F C     
1080 O O     . GLN C 10 ? 0.21528 0.37048 0.19154 -0.02299 0.00959  0.01542  174 GLN F O     
1081 C CB    . GLN C 10 ? 0.27262 0.42227 0.24074 0.02253  0.03678  0.08930  174 GLN F CB    
1082 C CG    . GLN C 10 ? 0.31793 0.46804 0.35455 0.01911  0.07106  0.12976  174 GLN F CG    
1083 C CD    . GLN C 10 ? 0.33920 0.51564 0.50297 0.00344  0.09180  0.15161  174 GLN F CD    
1084 O OE1   . GLN C 10 ? 0.38169 0.53762 0.49817 0.00383  0.11027  0.12262  174 GLN F OE1   
1085 N NE2   . GLN C 10 ? 0.30684 0.54421 0.64509 -0.00920 0.09910  0.16582  174 GLN F NE2   
1094 N N     . PHE C 11 ? 0.20608 0.33507 0.19343 -0.01982 0.00161  0.03238  175 PHE F N     
1095 C CA    . PHE C 11 ? 0.19573 0.31103 0.23774 -0.00943 0.01436  0.04483  175 PHE F CA    
1096 C C     . PHE C 11 ? 0.20029 0.31089 0.22371 -0.03401 0.02246  -0.00142 175 PHE F C     
1097 O O     . PHE C 11 ? 0.18768 0.30604 0.25030 -0.02077 0.00806  0.01817  175 PHE F O     
1098 C CB    . PHE C 11 ? 0.19892 0.32158 0.22443 0.00927  0.00537  0.01728  175 PHE F CB    
1099 C CG    . PHE C 11 ? 0.21226 0.29564 0.25399 -0.00943 0.02251  0.03505  175 PHE F CG    
1100 C CD1   . PHE C 11 ? 0.24350 0.32023 0.24996 -0.02212 0.02122  0.03495  175 PHE F CD1   
1101 C CD2   . PHE C 11 ? 0.21441 0.31446 0.21324 -0.02087 0.00444  0.02773  175 PHE F CD2   
1102 C CE1   . PHE C 11 ? 0.25956 0.32324 0.25913 -0.00485 -0.00205 0.03973  175 PHE F CE1   
1103 C CE2   . PHE C 11 ? 0.21674 0.32555 0.27546 -0.01746 -0.02391 0.03953  175 PHE F CE2   
1104 C CZ    . PHE C 11 ? 0.26481 0.32422 0.29876 -0.01138 0.00711  0.02747  175 PHE F CZ    
1114 N N     . LEU C 12 ? 0.17557 0.30485 0.20241 -0.02023 0.01001  0.02146  176 LEU F N     
1115 C CA    . LEU C 12 ? 0.19639 0.29039 0.19431 -0.03156 0.03696  0.01427  176 LEU F CA    
1116 C C     . LEU C 12 ? 0.19324 0.29989 0.19977 -0.00935 0.04388  -0.00064 176 LEU F C     
1117 O O     . LEU C 12 ? 0.21839 0.30094 0.20988 -0.00738 0.01495  0.01586  176 LEU F O     
1118 C CB    . LEU C 12 ? 0.19168 0.28614 0.18696 -0.02546 0.00407  0.02930  176 LEU F CB    
1119 C CG    . LEU C 12 ? 0.19561 0.27647 0.17931 -0.03866 0.04750  -0.00662 176 LEU F CG    
1120 C CD1   . LEU C 12 ? 0.19300 0.26432 0.22034 -0.02630 0.03790  -0.01898 176 LEU F CD1   
1121 C CD2   . LEU C 12 ? 0.20908 0.26043 0.19242 -0.01785 0.01664  -0.00255 176 LEU F CD2   
1133 N N     . LEU C 13 ? 0.19299 0.31966 0.18924 -0.00459 0.02915  -0.01149 177 LEU F N     
1134 C CA    . LEU C 13 ? 0.19947 0.35265 0.18063 0.00827  0.03519  -0.03206 177 LEU F CA    
1135 C C     . LEU C 13 ? 0.20248 0.36910 0.20904 -0.02791 0.02650  -0.00352 177 LEU F C     
1136 O O     . LEU C 13 ? 0.19958 0.38602 0.25657 -0.02742 0.03043  0.01375  177 LEU F O     
1137 C CB    . LEU C 13 ? 0.23710 0.39363 0.19927 0.01097  0.02643  -0.05262 177 LEU F CB    
1138 C CG    . LEU C 13 ? 0.27891 0.40687 0.24687 0.01444  0.04039  -0.05898 177 LEU F CG    
1139 C CD1   . LEU C 13 ? 0.25365 0.41565 0.26873 0.02038  0.04340  -0.06483 177 LEU F CD1   
1140 C CD2   . LEU C 13 ? 0.31032 0.41465 0.24961 0.01935  0.06666  -0.05959 177 LEU F CD2   
1152 N N     . ASP C 14 ? 0.19830 0.36428 0.21990 -0.05147 0.04017  0.01571  178 ASP F N     
1153 C CA    . ASP C 14 ? 0.22423 0.37952 0.27379 -0.04677 0.02968  0.05609  178 ASP F CA    
1154 C C     . ASP C 14 ? 0.24021 0.36189 0.26756 -0.03852 0.04314  0.06936  178 ASP F C     
1155 O O     . ASP C 14 ? 0.27430 0.37385 0.26268 -0.05946 0.04126  0.03993  178 ASP F O     
1156 C CB    . ASP C 14 ? 0.25216 0.41219 0.32659 -0.04282 0.00036  0.08022  178 ASP F CB    
1157 C CG    . ASP C 14 ? 0.33964 0.45103 0.45192 -0.05329 0.02203  0.09752  178 ASP F CG    
1158 O OD1   . ASP C 14 ? 0.41538 0.47046 0.35197 -0.06727 0.03294  0.08990  178 ASP F OD1   
1159 O OD2   . ASP C 14 ? 0.43839 0.47796 0.59335 -0.06969 0.04586  0.09700  178 ASP F OD2   
1164 N N     . LEU C 15 ? 0.21098 0.32859 0.26527 -0.01070 0.01555  0.06684  179 LEU F N     
1165 C CA    . LEU C 15 ? 0.24168 0.30418 0.29381 -0.00108 0.03914  0.05903  179 LEU F CA    
1166 C C     . LEU C 15 ? 0.24431 0.29986 0.30891 -0.02990 0.03587  0.06263  179 LEU F C     
1167 O O     . LEU C 15 ? 0.24959 0.31035 0.37752 -0.04845 0.02729  0.05797  179 LEU F O     
1168 C CB    . LEU C 15 ? 0.24955 0.32784 0.32457 0.00324  0.05360  0.06910  179 LEU F CB    
1169 C CG    . LEU C 15 ? 0.33273 0.34093 0.34258 0.03157  0.08786  0.10302  179 LEU F CG    
1170 C CD1   . LEU C 15 ? 0.33147 0.35388 0.34406 0.03012  0.08964  0.10895  179 LEU F CD1   
1171 C CD2   . LEU C 15 ? 0.41009 0.33271 0.37326 0.09002  0.13694  0.15820  179 LEU F CD2   
1183 N N     . LEU C 16 ? 0.20823 0.30548 0.28188 -0.03610 -0.01387 0.05451  180 LEU F N     
1184 C CA    . LEU C 16 ? 0.20237 0.33516 0.27118 -0.03187 -0.00102 0.05860  180 LEU F CA    
1185 C C     . LEU C 16 ? 0.23099 0.38651 0.31369 -0.03502 0.02608  0.07884  180 LEU F C     
1186 O O     . LEU C 16 ? 0.26148 0.40621 0.33132 -0.06044 0.04709  0.03511  180 LEU F O     
1187 C CB    . LEU C 16 ? 0.21778 0.33454 0.22326 0.01440  0.01480  0.05903  180 LEU F CB    
1188 C CG    . LEU C 16 ? 0.17191 0.30917 0.24169 -0.00732 -0.02890 0.03086  180 LEU F CG    
1189 C CD1   . LEU C 16 ? 0.20936 0.29670 0.27520 -0.00734 -0.01235 0.00387  180 LEU F CD1   
1190 C CD2   . LEU C 16 ? 0.22200 0.30871 0.27540 0.01412  0.00637  0.03275  180 LEU F CD2   
1202 N N     . ARG C 17 ? 0.21275 0.43462 0.33590 -0.08668 0.03134  0.09956  181 ARG F N     
1203 C CA    . ARG C 17 ? 0.26434 0.50059 0.37387 -0.10440 0.06111  0.14538  181 ARG F CA    
1204 C C     . ARG C 17 ? 0.29697 0.51176 0.44905 -0.12543 0.04864  0.16628  181 ARG F C     
1205 O O     . ARG C 17 ? 0.34335 0.54325 0.53222 -0.11963 0.09110  0.16301  181 ARG F O     
1206 C CB    . ARG C 17 ? 0.29425 0.55793 0.37378 -0.10814 0.04009  0.11899  181 ARG F CB    
1207 C CG    . ARG C 17 ? 0.33859 0.61610 0.41365 -0.10195 0.01282  0.04952  181 ARG F CG    
1208 C CD    . ARG C 17 ? 0.42770 0.66345 0.45952 -0.08088 0.04292  0.02471  181 ARG F CD    
1209 N NE    . ARG C 17 ? 0.46869 0.69662 0.45709 -0.09175 0.07906  0.01612  181 ARG F NE    
1210 C CZ    . ARG C 17 ? 0.46103 0.72256 0.40622 -0.07806 0.00483  0.03677  181 ARG F CZ    
1211 N NH1   . ARG C 17 ? 0.41585 0.72695 0.33207 -0.05275 -0.07240 0.05361  181 ARG F NH1   
1212 N NH2   . ARG C 17 ? 0.47572 0.73844 0.41163 -0.07951 0.02681  0.03689  181 ARG F NH2   
1226 N N     . SER C 18 ? 0.30082 0.50074 0.47295 -0.12563 0.00096  0.18087  182 SER F N     
1227 C CA    . SER C 18 ? 0.34326 0.49852 0.51972 -0.13300 -0.00555 0.19163  182 SER F CA    
1228 C C     . SER C 18 ? 0.36277 0.49203 0.55419 -0.16130 0.02606  0.15645  182 SER F C     
1229 O O     . SER C 18 ? 0.38728 0.48000 0.60669 -0.16103 0.05633  0.15505  182 SER F O     
1230 C CB    . SER C 18 ? 0.40319 0.49881 0.54769 -0.10835 -0.00126 0.20287  182 SER F CB    
1231 O OG    . SER C 18 ? 0.41310 0.49972 0.52565 -0.09562 -0.04232 0.20885  182 SER F OG    
1237 N N     . GLY C 19 ? 0.41145 0.50376 0.54696 -0.12409 -0.00842 0.14797  183 GLY F N     
1238 C CA    . GLY C 19 ? 0.39018 0.51352 0.54134 -0.12334 -0.04718 0.13671  183 GLY F CA    
1239 C C     . GLY C 19 ? 0.42404 0.52025 0.54651 -0.10968 -0.02344 0.11969  183 GLY F C     
1240 O O     . GLY C 19 ? 0.41897 0.51954 0.55944 -0.12059 -0.05339 0.09066  183 GLY F O     
1244 N N     . ASP C 20 ? 0.37943 0.51597 0.51116 -0.07084 -0.06519 0.16898  184 ASP F N     
1245 C CA    . ASP C 20 ? 0.38996 0.50928 0.54168 -0.04715 -0.02024 0.15253  184 ASP F CA    
1246 C C     . ASP C 20 ? 0.40069 0.43984 0.52019 -0.02756 -0.01127 0.12337  184 ASP F C     
1247 O O     . ASP C 20 ? 0.50678 0.44703 0.56956 -0.02922 0.06022  0.11589  184 ASP F O     
1248 C CB    . ASP C 20 ? 0.38733 0.55394 0.60099 -0.05191 0.00345  0.17069  184 ASP F CB    
1249 C CG    . ASP C 20 ? 0.38700 0.59503 0.65807 -0.05233 0.02807  0.17921  184 ASP F CG    
1250 O OD1   . ASP C 20 ? 0.40387 0.61026 0.68396 -0.04943 0.06691  0.19045  184 ASP F OD1   
1251 O OD2   . ASP C 20 ? 0.36430 0.61584 0.67180 -0.05523 0.01931  0.19783  184 ASP F OD2   
1256 N N     . MET C 21 ? 0.31309 0.36238 0.46357 -0.04944 -0.02946 0.07355  185 MET F N     
1257 C CA    . MET C 21 ? 0.28744 0.30973 0.44384 -0.02724 -0.00641 0.01868  185 MET F CA    
1258 C C     . MET C 21 ? 0.31894 0.29493 0.44112 -0.01420 0.00171  0.03551  185 MET F C     
1259 O O     . MET C 21 ? 0.30787 0.25603 0.39646 -0.02698 -0.03902 0.01216  185 MET F O     
1260 C CB    . MET C 21 ? 0.26803 0.30912 0.44293 0.00421  -0.00745 0.05054  185 MET F CB    
1261 C CG    . MET C 21 ? 0.30641 0.32586 0.46347 -0.00930 0.04699  0.04902  185 MET F CG    
1262 S SD    . MET C 21 ? 0.32556 0.30423 0.43777 -0.03470 0.02096  0.02939  185 MET F SD    
1263 C CE    . MET C 21 ? 0.30118 0.28319 0.43739 -0.05926 0.01307  0.02799  185 MET F CE    
1273 N N     . LYS C 22 ? 0.29847 0.33350 0.50888 -0.05110 0.00309  0.02528  186 LYS F N     
1274 C CA    . LYS C 22 ? 0.28902 0.40779 0.52269 -0.06262 -0.02307 0.02149  186 LYS F CA    
1275 C C     . LYS C 22 ? 0.31536 0.35698 0.46977 -0.06733 -0.05379 -0.01161 186 LYS F C     
1276 O O     . LYS C 22 ? 0.33250 0.34228 0.44294 -0.04373 -0.04671 0.00066  186 LYS F O     
1277 C CB    . LYS C 22 ? 0.34647 0.51541 0.65862 -0.08436 0.06706  0.00507  186 LYS F CB    
1278 C CG    . LYS C 22 ? 0.47927 0.59847 0.77121 -0.06664 0.18189  -0.00200 186 LYS F CG    
1279 C CD    . LYS C 22 ? 0.58456 0.65750 0.86953 -0.03391 0.27984  -0.00083 186 LYS F CD    
1280 C CE    . LYS C 22 ? 0.67525 0.69360 0.95538 -0.02807 0.33715  -0.00749 186 LYS F CE    
1281 N NZ    . LYS C 22 ? 0.70246 0.70063 0.97919 -0.04269 0.37803  -0.00374 186 LYS F NZ    
1295 N N     . ASP C 23 ? 0.33714 0.32046 0.46673 -0.09090 -0.05988 -0.02848 187 ASP F N     
1296 C CA    . ASP C 23 ? 0.35987 0.30394 0.44858 -0.08437 -0.07948 -0.04942 187 ASP F CA    
1297 C C     . ASP C 23 ? 0.28112 0.27848 0.39262 -0.03519 -0.08101 -0.05378 187 ASP F C     
1298 O O     . ASP C 23 ? 0.27933 0.29965 0.35878 -0.01051 -0.06104 -0.05805 187 ASP F O     
1299 C CB    . ASP C 23 ? 0.44517 0.33040 0.54443 -0.12058 -0.05084 -0.06881 187 ASP F CB    
1300 C CG    . ASP C 23 ? 0.53547 0.37372 0.65346 -0.12432 -0.02460 -0.04839 187 ASP F CG    
1301 O OD1   . ASP C 23 ? 0.52752 0.39805 0.67965 -0.16321 -0.02459 -0.06861 187 ASP F OD1   
1302 O OD2   . ASP C 23 ? 0.62252 0.39419 0.70547 -0.10425 0.03360  -0.01885 187 ASP F OD2   
1307 N N     . SER C 24 ? 0.26571 0.26038 0.35093 -0.02396 -0.04671 -0.04614 188 SER F N     
1308 C CA    . SER C 24 ? 0.23034 0.23965 0.32652 0.00800  -0.00879 -0.03998 188 SER F CA    
1309 C C     . SER C 24 ? 0.20770 0.24804 0.30262 0.00625  -0.02486 -0.02628 188 SER F C     
1310 O O     . SER C 24 ? 0.20493 0.25622 0.27017 -0.00360 -0.00700 -0.03073 188 SER F O     
1311 C CB    . SER C 24 ? 0.23572 0.23864 0.29628 0.04074  -0.04097 -0.03049 188 SER F CB    
1312 O OG    . SER C 24 ? 0.26049 0.26318 0.32729 0.03444  -0.02379 -0.03290 188 SER F OG    
1318 N N     . ILE C 25 ? 0.21326 0.25243 0.28759 -0.02545 -0.00036 -0.01929 189 ILE F N     
1319 C CA    . ILE C 25 ? 0.18323 0.25169 0.27494 -0.01086 0.00678  -0.02869 189 ILE F CA    
1320 C C     . ILE C 25 ? 0.15933 0.26314 0.30771 -0.04139 0.00626  -0.03389 189 ILE F C     
1321 O O     . ILE C 25 ? 0.21780 0.28330 0.33016 -0.05021 0.01435  -0.00820 189 ILE F O     
1322 C CB    . ILE C 25 ? 0.18000 0.25495 0.24319 -0.01715 -0.00158 -0.02322 189 ILE F CB    
1323 C CG1   . ILE C 25 ? 0.18941 0.27595 0.25344 -0.00081 -0.00298 -0.00296 189 ILE F CG1   
1324 C CG2   . ILE C 25 ? 0.22860 0.28099 0.28495 -0.00436 0.01957  -0.03445 189 ILE F CG2   
1325 C CD1   . ILE C 25 ? 0.19234 0.28176 0.25987 0.02089  0.00048  -0.02158 189 ILE F CD1   
1337 N N     . TRP C 26 ? 0.15723 0.27872 0.28437 -0.00690 -0.00362 -0.00974 190 TRP F N     
1338 C CA    . TRP C 26 ? 0.15280 0.28374 0.25950 0.00033  -0.02303 -0.00020 190 TRP F CA    
1339 C C     . TRP C 26 ? 0.16111 0.28297 0.29021 -0.00893 0.01626  -0.00720 190 TRP F C     
1340 O O     . TRP C 26 ? 0.19061 0.28469 0.24920 -0.01210 0.00676  -0.00757 190 TRP F O     
1341 C CB    . TRP C 26 ? 0.18621 0.27927 0.31493 -0.03239 -0.01485 -0.02622 190 TRP F CB    
1342 C CG    . TRP C 26 ? 0.19572 0.27693 0.30771 -0.03689 -0.02585 -0.04773 190 TRP F CG    
1343 C CD1   . TRP C 26 ? 0.23270 0.31263 0.29513 -0.03396 -0.03345 -0.07064 190 TRP F CD1   
1344 C CD2   . TRP C 26 ? 0.18548 0.29934 0.31859 -0.02044 -0.06465 -0.03986 190 TRP F CD2   
1345 N NE1   . TRP C 26 ? 0.22660 0.31785 0.31087 -0.01034 -0.05433 -0.02765 190 TRP F NE1   
1346 C CE2   . TRP C 26 ? 0.19506 0.31335 0.32248 -0.02557 -0.05382 -0.04281 190 TRP F CE2   
1347 C CE3   . TRP C 26 ? 0.20089 0.30775 0.34477 0.00289  -0.03222 -0.01725 190 TRP F CE3   
1348 C CZ2   . TRP C 26 ? 0.20549 0.32713 0.29923 -0.02658 -0.05263 -0.03471 190 TRP F CZ2   
1349 C CZ3   . TRP C 26 ? 0.24965 0.31744 0.34709 0.00255  0.00908  -0.04152 190 TRP F CZ3   
1350 C CH2   . TRP C 26 ? 0.22612 0.31968 0.32505 -0.01002 -0.01954 -0.03798 190 TRP F CH2   
1361 N N     . TRP C 27 ? 0.15369 0.28792 0.30592 -0.00998 0.02645  -0.01693 191 TRP F N     
1362 C CA    . TRP C 27 ? 0.15590 0.29738 0.31354 0.01968  0.01889  -0.00428 191 TRP F CA    
1363 C C     . TRP C 27 ? 0.14664 0.30267 0.30126 -0.00270 -0.02143 -0.01055 191 TRP F C     
1364 O O     . TRP C 27 ? 0.18641 0.31680 0.31135 -0.00722 -0.02726 -0.01014 191 TRP F O     
1365 C CB    . TRP C 27 ? 0.19175 0.31242 0.29131 -0.01236 0.03885  0.01998  191 TRP F CB    
1366 C CG    . TRP C 27 ? 0.19623 0.33884 0.28845 -0.01553 0.03272  -0.01274 191 TRP F CG    
1367 C CD1   . TRP C 27 ? 0.20848 0.34080 0.27377 -0.04082 0.03730  -0.00679 191 TRP F CD1   
1368 C CD2   . TRP C 27 ? 0.18174 0.34851 0.27073 -0.00836 0.03076  -0.00336 191 TRP F CD2   
1369 N NE1   . TRP C 27 ? 0.20291 0.34431 0.28283 -0.05060 0.01378  -0.02978 191 TRP F NE1   
1370 C CE2   . TRP C 27 ? 0.17334 0.34450 0.27214 -0.02564 0.00116  -0.01796 191 TRP F CE2   
1371 C CE3   . TRP C 27 ? 0.19254 0.34303 0.25367 -0.03362 0.03084  -0.01102 191 TRP F CE3   
1372 C CZ2   . TRP C 27 ? 0.19896 0.35531 0.27117 -0.00755 0.02116  -0.05416 191 TRP F CZ2   
1373 C CZ3   . TRP C 27 ? 0.18065 0.34611 0.26524 -0.00619 0.00612  -0.00992 191 TRP F CZ3   
1374 C CH2   . TRP C 27 ? 0.19643 0.35504 0.27108 0.00228  0.02738  -0.03657 191 TRP F CH2   
1385 N N     . VAL C 28 ? 0.18390 0.31779 0.26429 0.00574  0.00858  -0.02153 192 VAL F N     
1386 C CA    . VAL C 28 ? 0.16095 0.33921 0.26025 0.02623  0.02322  -0.00150 192 VAL F CA    
1387 C C     . VAL C 28 ? 0.15159 0.35400 0.22755 -0.00228 -0.02495 -0.01579 192 VAL F C     
1388 O O     . VAL C 28 ? 0.16075 0.38068 0.28546 0.00260  -0.02483 -0.00740 192 VAL F O     
1389 C CB    . VAL C 28 ? 0.16465 0.35362 0.25708 0.03751  0.01650  0.01519  192 VAL F CB    
1390 C CG1   . VAL C 28 ? 0.19651 0.36540 0.28627 0.03994  0.01461  0.02596  192 VAL F CG1   
1391 C CG2   . VAL C 28 ? 0.17937 0.35671 0.25056 0.00634  0.01520  0.02897  192 VAL F CG2   
1401 N N     . ASP C 29 ? 0.18301 0.34600 0.25029 -0.00836 -0.00112 -0.01925 193 ASP F N     
1402 C CA    . ASP C 29 ? 0.19227 0.35369 0.24977 -0.00440 0.02290  -0.02780 193 ASP F CA    
1403 C C     . ASP C 29 ? 0.21310 0.34234 0.26260 0.01918  0.02463  -0.01860 193 ASP F C     
1404 O O     . ASP C 29 ? 0.18906 0.30781 0.25428 0.01143  -0.00036 0.01212  193 ASP F O     
1405 C CB    . ASP C 29 ? 0.20168 0.38680 0.26690 0.02813  -0.06228 -0.02782 193 ASP F CB    
1406 C CG    . ASP C 29 ? 0.19877 0.42886 0.30128 0.04825  -0.04483 -0.03958 193 ASP F CG    
1407 O OD1   . ASP C 29 ? 0.19450 0.46658 0.27064 0.05067  -0.02442 -0.07616 193 ASP F OD1   
1408 O OD2   . ASP C 29 ? 0.20711 0.44078 0.33129 0.04350  -0.04149 -0.04241 193 ASP F OD2   
1413 N N     . LYS C 30 ? 0.28603 0.37138 0.28692 0.03015  0.05485  -0.00749 194 LYS F N     
1414 C CA    . LYS C 30 ? 0.37143 0.37948 0.28791 0.02304  0.09687  0.04190  194 LYS F CA    
1415 C C     . LYS C 30 ? 0.34362 0.37748 0.26212 0.02711  0.06214  0.02929  194 LYS F C     
1416 O O     . LYS C 30 ? 0.36519 0.37571 0.24330 0.04602  0.04205  0.02014  194 LYS F O     
1417 C CB    . LYS C 30 ? 0.41475 0.42591 0.38647 -0.01733 0.20104  0.03816  194 LYS F CB    
1418 C CG    . LYS C 30 ? 0.41012 0.45519 0.42321 -0.03569 0.17648  0.07767  194 LYS F CG    
1419 C CD    . LYS C 30 ? 0.50256 0.48271 0.49290 -0.07815 0.21520  0.10233  194 LYS F CD    
1420 C CE    . LYS C 30 ? 0.58719 0.49631 0.54138 -0.10583 0.25187  0.09167  194 LYS F CE    
1421 N NZ    . LYS C 30 ? 0.63459 0.52207 0.57497 -0.10023 0.25109  0.09655  194 LYS F NZ    
1435 N N     . ASP C 31 ? 0.28416 0.39416 0.25656 0.03384  0.05071  -0.02259 195 ASP F N     
1436 C CA    . ASP C 31 ? 0.24661 0.38649 0.28554 0.02690  0.05879  -0.03969 195 ASP F CA    
1437 C C     . ASP C 31 ? 0.27147 0.38758 0.28804 0.02763  0.05173  -0.04947 195 ASP F C     
1438 O O     . ASP C 31 ? 0.32259 0.40509 0.28918 0.01462  0.03628  -0.03521 195 ASP F O     
1439 C CB    . ASP C 31 ? 0.24106 0.39900 0.29070 0.00952  0.06067  -0.02561 195 ASP F CB    
1440 C CG    . ASP C 31 ? 0.26512 0.42833 0.26909 0.00699  0.04435  -0.02570 195 ASP F CG    
1441 O OD1   . ASP C 31 ? 0.23486 0.45219 0.30263 0.00073  0.00131  -0.03381 195 ASP F OD1   
1442 O OD2   . ASP C 31 ? 0.27108 0.44926 0.30453 0.02623  0.05175  0.01661  195 ASP F OD2   
1447 N N     . LYS C 32 ? 0.23503 0.37202 0.23717 0.04880  0.02925  -0.01915 196 LYS F N     
1448 C CA    . LYS C 32 ? 0.22977 0.35322 0.26612 0.05269  0.01037  -0.01602 196 LYS F CA    
1449 C C     . LYS C 32 ? 0.21182 0.32785 0.26148 0.02033  0.00644  -0.03252 196 LYS F C     
1450 O O     . LYS C 32 ? 0.26206 0.32183 0.27657 0.02630  -0.00581 -0.03939 196 LYS F O     
1451 C CB    . LYS C 32 ? 0.25924 0.37789 0.27589 0.05236  0.01249  -0.00674 196 LYS F CB    
1452 C CG    . LYS C 32 ? 0.27625 0.38814 0.32302 0.03544  -0.04897 -0.00673 196 LYS F CG    
1453 C CD    . LYS C 32 ? 0.27867 0.40364 0.37955 0.01557  -0.08547 -0.02990 196 LYS F CD    
1454 C CE    . LYS C 32 ? 0.35737 0.43047 0.42652 0.07916  -0.10058 0.01043  196 LYS F CE    
1455 N NZ    . LYS C 32 ? 0.38348 0.45510 0.44606 0.09156  -0.09228 0.02936  196 LYS F NZ    
1469 N N     . GLY C 33 ? 0.24346 0.33135 0.25527 0.05512  0.02907  -0.00903 197 GLY F N     
1470 C CA    . GLY C 33 ? 0.22721 0.32654 0.24917 0.04041  0.00055  -0.02428 197 GLY F CA    
1471 C C     . GLY C 33 ? 0.21556 0.29928 0.23802 0.02382  -0.04697 -0.01144 197 GLY F C     
1472 O O     . GLY C 33 ? 0.22403 0.27095 0.27019 0.01216  -0.04651 -0.01956 197 GLY F O     
1476 N N     . THR C 34 ? 0.20183 0.28346 0.25823 0.00885  -0.01462 -0.02150 198 THR F N     
1477 C CA    . THR C 34 ? 0.17966 0.27437 0.25337 0.01276  -0.02540 -0.04430 198 THR F CA    
1478 C C     . THR C 34 ? 0.17393 0.26452 0.25943 -0.01912 -0.01346 -0.03285 198 THR F C     
1479 O O     . THR C 34 ? 0.17428 0.26522 0.28236 0.00481  -0.00147 -0.04086 198 THR F O     
1480 C CB    . THR C 34 ? 0.19199 0.27961 0.22195 0.00534  -0.01334 -0.01677 198 THR F CB    
1481 O OG1   . THR C 34 ? 0.16639 0.31196 0.29767 0.00940  -0.00058 0.00724  198 THR F OG1   
1482 C CG2   . THR C 34 ? 0.22221 0.30384 0.22201 0.01340  -0.01238 -0.02484 198 THR F CG2   
1490 N N     . PHE C 35 ? 0.16447 0.24900 0.24712 -0.01841 0.01351  -0.02866 199 PHE F N     
1491 C CA    . PHE C 35 ? 0.18872 0.25283 0.21355 -0.00610 0.01304  -0.01448 199 PHE F CA    
1492 C C     . PHE C 35 ? 0.17162 0.25309 0.21507 -0.00393 -0.00011 -0.00779 199 PHE F C     
1493 O O     . PHE C 35 ? 0.20470 0.26085 0.22321 -0.02442 0.01097  -0.01678 199 PHE F O     
1494 C CB    . PHE C 35 ? 0.20808 0.26725 0.22329 0.01034  0.01999  -0.01434 199 PHE F CB    
1495 C CG    . PHE C 35 ? 0.18036 0.25433 0.24610 0.02172  0.01781  -0.01308 199 PHE F CG    
1496 C CD1   . PHE C 35 ? 0.15684 0.26215 0.23943 0.02224  0.00954  -0.02352 199 PHE F CD1   
1497 C CD2   . PHE C 35 ? 0.17468 0.28341 0.24848 0.01030  -0.01401 0.01860  199 PHE F CD2   
1498 C CE1   . PHE C 35 ? 0.19135 0.26757 0.20831 0.02662  -0.00529 -0.00063 199 PHE F CE1   
1499 C CE2   . PHE C 35 ? 0.20293 0.28338 0.21613 0.00731  0.01551  0.00265  199 PHE F CE2   
1500 C CZ    . PHE C 35 ? 0.18035 0.26759 0.22097 0.00711  -0.00034 -0.00132 199 PHE F CZ    
1510 N N     . GLN C 36 ? 0.17307 0.26404 0.20157 -0.00456 0.00247  -0.01973 200 GLN F N     
1511 C CA    . GLN C 36 ? 0.16431 0.26258 0.24000 0.01172  -0.01721 -0.02736 200 GLN F CA    
1512 C C     . GLN C 36 ? 0.14478 0.25697 0.24094 -0.01238 -0.00721 -0.01266 200 GLN F C     
1513 O O     . GLN C 36 ? 0.17584 0.25205 0.24775 -0.02265 0.00406  -0.01192 200 GLN F O     
1514 C CB    . GLN C 36 ? 0.21269 0.28284 0.24200 0.01437  -0.01536 -0.01631 200 GLN F CB    
1515 C CG    . GLN C 36 ? 0.20560 0.31957 0.25654 0.00966  -0.02287 0.00040  200 GLN F CG    
1516 C CD    . GLN C 36 ? 0.25020 0.35264 0.28997 -0.00601 -0.05194 0.01707  200 GLN F CD    
1517 O OE1   . GLN C 36 ? 0.26002 0.34854 0.34219 -0.03691 -0.07414 0.01960  200 GLN F OE1   
1518 N NE2   . GLN C 36 ? 0.26447 0.36541 0.30440 0.00746  -0.05988 0.03785  200 GLN F NE2   
1527 N N     . PHE C 37 ? 0.16233 0.24935 0.22893 -0.01178 -0.00175 -0.02374 201 PHE F N     
1528 C CA    . PHE C 37 ? 0.19088 0.24911 0.20937 0.00143  -0.01919 -0.03565 201 PHE F CA    
1529 C C     . PHE C 37 ? 0.22181 0.25982 0.26075 -0.00756 -0.01087 -0.03038 201 PHE F C     
1530 O O     . PHE C 37 ? 0.22711 0.26881 0.24681 -0.01295 -0.00869 -0.02207 201 PHE F O     
1531 C CB    . PHE C 37 ? 0.17882 0.24428 0.22542 -0.01185 -0.02134 -0.03514 201 PHE F CB    
1532 C CG    . PHE C 37 ? 0.16845 0.26293 0.22625 -0.00669 -0.01026 -0.02998 201 PHE F CG    
1533 C CD1   . PHE C 37 ? 0.19812 0.26330 0.22289 0.01021  -0.01524 -0.01209 201 PHE F CD1   
1534 C CD2   . PHE C 37 ? 0.16327 0.28458 0.18939 -0.01352 -0.02339 -0.02139 201 PHE F CD2   
1535 C CE1   . PHE C 37 ? 0.21451 0.24732 0.22553 0.03207  0.01096  -0.02179 201 PHE F CE1   
1536 C CE2   . PHE C 37 ? 0.18850 0.27657 0.20133 0.00826  -0.02293 -0.03127 201 PHE F CE2   
1537 C CZ    . PHE C 37 ? 0.20165 0.24639 0.20536 0.02205  -0.01211 -0.02320 201 PHE F CZ    
1547 N N     . SER C 38 ? 0.23545 0.27246 0.23236 0.00910  -0.03571 -0.02871 202 SER F N     
1548 C CA    . SER C 38 ? 0.24217 0.28564 0.27011 0.00769  -0.06032 -0.04971 202 SER F CA    
1549 C C     . SER C 38 ? 0.26671 0.31352 0.21266 -0.02144 -0.06244 -0.06320 202 SER F C     
1550 O O     . SER C 38 ? 0.23534 0.33710 0.22148 -0.01654 -0.06209 -0.04592 202 SER F O     
1551 C CB    . SER C 38 ? 0.24705 0.28586 0.29249 -0.01787 -0.05913 -0.05702 202 SER F CB    
1552 O OG    . SER C 38 ? 0.29771 0.28054 0.29972 -0.00199 -0.03493 -0.08252 202 SER F OG    
1558 N N     . SER C 39 ? 0.30480 0.35772 0.22692 -0.02502 -0.06218 -0.04752 203 SER F N     
1559 C CA    . SER C 39 ? 0.36210 0.38572 0.18447 -0.02085 -0.06568 -0.02666 203 SER F CA    
1560 C C     . SER C 39 ? 0.32389 0.37787 0.25372 -0.03144 -0.05710 -0.05559 203 SER F C     
1561 O O     . SER C 39 ? 0.29306 0.38073 0.28220 -0.04413 -0.01818 -0.09421 203 SER F O     
1562 C CB    . SER C 39 ? 0.44793 0.40813 0.18775 -0.01700 -0.05106 0.00059  203 SER F CB    
1563 O OG    . SER C 39 ? 0.59298 0.43095 0.25297 -0.04554 0.04369  -0.00220 203 SER F OG    
1569 N N     . LYS C 40 ? 0.34385 0.37503 0.26215 -0.01398 -0.06090 -0.07407 204 LYS F N     
1570 C CA    . LYS C 40 ? 0.34753 0.34774 0.29379 -0.04198 -0.06478 -0.12296 204 LYS F CA    
1571 C C     . LYS C 40 ? 0.31285 0.33812 0.30326 -0.04004 -0.07641 -0.12719 204 LYS F C     
1572 O O     . LYS C 40 ? 0.35296 0.37277 0.31559 -0.00928 -0.01045 -0.08968 204 LYS F O     
1573 C CB    . LYS C 40 ? 0.42064 0.37035 0.37956 -0.05570 -0.04284 -0.11347 204 LYS F CB    
1574 C CG    . LYS C 40 ? 0.46486 0.39533 0.45293 -0.04433 -0.03168 -0.09147 204 LYS F CG    
1575 C CD    . LYS C 40 ? 0.50957 0.40745 0.53489 -0.02096 0.01751  -0.06784 204 LYS F CD    
1576 C CE    . LYS C 40 ? 0.54486 0.42199 0.58792 -0.01475 0.05310  -0.05424 204 LYS F CE    
1577 N NZ    . LYS C 40 ? 0.57194 0.43133 0.60828 -0.00382 0.06770  -0.04458 204 LYS F NZ    
1591 N N     . HIS C 41 ? 0.27610 0.31819 0.28811 -0.00915 -0.07492 -0.10154 205 HIS F N     
1592 C CA    . HIS C 41 ? 0.23402 0.29650 0.32132 -0.02341 -0.06273 -0.08891 205 HIS F CA    
1593 C C     . HIS C 41 ? 0.25163 0.27835 0.26720 -0.00891 -0.04935 -0.06829 205 HIS F C     
1594 O O     . HIS C 41 ? 0.27419 0.25864 0.30080 -0.01570 -0.04381 -0.03661 205 HIS F O     
1595 C CB    . HIS C 41 ? 0.21869 0.29708 0.36202 0.00626  -0.05692 -0.08957 205 HIS F CB    
1596 C CG    . HIS C 41 ? 0.26347 0.31322 0.38179 -0.01998 -0.06444 -0.10794 205 HIS F CG    
1597 N ND1   . HIS C 41 ? 0.31058 0.32838 0.36215 -0.03457 -0.07446 -0.11250 205 HIS F ND1   
1598 C CD2   . HIS C 41 ? 0.27197 0.31629 0.45950 0.00335  -0.08205 -0.09874 205 HIS F CD2   
1599 C CE1   . HIS C 41 ? 0.31614 0.32229 0.39493 -0.03023 -0.06170 -0.13151 205 HIS F CE1   
1600 N NE2   . HIS C 41 ? 0.33250 0.32459 0.43885 -0.02927 -0.05814 -0.11976 205 HIS F NE2   
1608 N N     . LYS C 42 ? 0.25974 0.26558 0.23186 -0.03140 -0.02958 -0.05984 206 LYS F N     
1609 C CA    . LYS C 42 ? 0.24977 0.25846 0.23067 -0.02377 -0.02828 -0.05434 206 LYS F CA    
1610 C C     . LYS C 42 ? 0.23339 0.26397 0.23441 -0.00032 -0.02107 -0.03857 206 LYS F C     
1611 O O     . LYS C 42 ? 0.23003 0.25299 0.22855 -0.01279 -0.01909 -0.01729 206 LYS F O     
1612 C CB    . LYS C 42 ? 0.22454 0.24673 0.23291 -0.00183 -0.02110 -0.03447 206 LYS F CB    
1613 C CG    . LYS C 42 ? 0.21958 0.25923 0.22382 -0.00932 -0.01869 -0.03042 206 LYS F CG    
1614 C CD    . LYS C 42 ? 0.22782 0.28800 0.25634 -0.03057 -0.02883 -0.01383 206 LYS F CD    
1615 C CE    . LYS C 42 ? 0.26496 0.31883 0.22021 -0.04760 -0.03837 -0.01526 206 LYS F CE    
1616 N NZ    . LYS C 42 ? 0.28654 0.32616 0.26269 -0.03163 -0.03868 0.00058  206 LYS F NZ    
1630 N N     . GLU C 43 ? 0.22737 0.26746 0.23172 0.00933  -0.00387 -0.04410 207 GLU F N     
1631 C CA    . GLU C 43 ? 0.23871 0.28133 0.21502 0.00755  -0.01873 -0.07235 207 GLU F CA    
1632 C C     . GLU C 43 ? 0.20735 0.26837 0.24660 0.00597  -0.04034 -0.07108 207 GLU F C     
1633 O O     . GLU C 43 ? 0.22535 0.26895 0.25184 0.00695  -0.02193 -0.07114 207 GLU F O     
1634 C CB    . GLU C 43 ? 0.30073 0.30593 0.28163 -0.00437 0.02199  -0.10282 207 GLU F CB    
1635 C CG    . GLU C 43 ? 0.39385 0.33159 0.40288 -0.04797 0.08976  -0.09206 207 GLU F CG    
1636 C CD    . GLU C 43 ? 0.46362 0.36867 0.47688 -0.09468 0.14734  -0.08636 207 GLU F CD    
1637 O OE1   . GLU C 43 ? 0.39482 0.40429 0.33973 -0.10503 0.00225  -0.04749 207 GLU F OE1   
1638 O OE2   . GLU C 43 ? 0.53779 0.37814 0.59518 -0.13077 0.19622  -0.11924 207 GLU F OE2   
1645 N N     . ALA C 44 ? 0.23822 0.25754 0.27310 0.02145  -0.04063 -0.05632 208 ALA F N     
1646 C CA    . ALA C 44 ? 0.26804 0.24299 0.27248 0.00160  -0.01549 -0.05330 208 ALA F CA    
1647 C C     . ALA C 44 ? 0.24132 0.23658 0.25743 0.01501  -0.04255 -0.04195 208 ALA F C     
1648 O O     . ALA C 44 ? 0.24970 0.25899 0.27898 0.02706  -0.02050 -0.05782 208 ALA F O     
1649 C CB    . ALA C 44 ? 0.31685 0.23319 0.31165 -0.00283 -0.01808 -0.02836 208 ALA F CB    
1655 N N     . LEU C 45 ? 0.22210 0.23018 0.26638 0.02385  -0.03199 -0.05451 209 LEU F N     
1656 C CA    . LEU C 45 ? 0.18367 0.24301 0.24444 0.01209  -0.02669 -0.01640 209 LEU F CA    
1657 C C     . LEU C 45 ? 0.21628 0.24741 0.20456 0.00183  -0.00060 -0.03848 209 LEU F C     
1658 O O     . LEU C 45 ? 0.21646 0.25770 0.18994 0.00300  -0.01415 -0.03322 209 LEU F O     
1659 C CB    . LEU C 45 ? 0.21034 0.24290 0.21245 0.00152  -0.00358 -0.02205 209 LEU F CB    
1660 C CG    . LEU C 45 ? 0.20764 0.24154 0.20382 -0.00457 -0.00348 -0.03767 209 LEU F CG    
1661 C CD1   . LEU C 45 ? 0.22519 0.25706 0.26239 -0.00532 0.00406  -0.04546 209 LEU F CD1   
1662 C CD2   . LEU C 45 ? 0.22651 0.24383 0.28452 -0.04081 -0.00680 -0.03500 209 LEU F CD2   
1674 N N     . ALA C 46 ? 0.19514 0.25734 0.22635 0.00453  0.00488  -0.03153 210 ALA F N     
1675 C CA    . ALA C 46 ? 0.18924 0.26505 0.23435 0.00310  0.01763  -0.03876 210 ALA F CA    
1676 C C     . ALA C 46 ? 0.21725 0.26194 0.24418 0.00485  -0.00852 -0.06453 210 ALA F C     
1677 O O     . ALA C 46 ? 0.22950 0.26044 0.24527 0.01180  -0.00649 -0.06019 210 ALA F O     
1678 C CB    . ALA C 46 ? 0.19563 0.27371 0.23776 -0.03139 0.00772  -0.05543 210 ALA F CB    
1684 N N     . HIS C 47 ? 0.21047 0.25831 0.28250 0.01423  -0.02730 -0.05842 211 HIS F N     
1685 C CA    . HIS C 47 ? 0.22684 0.27002 0.29573 0.02640  -0.06461 -0.06153 211 HIS F CA    
1686 C C     . HIS C 47 ? 0.24373 0.26868 0.29113 0.02292  -0.08435 -0.06122 211 HIS F C     
1687 O O     . HIS C 47 ? 0.26357 0.29947 0.34011 0.01310  -0.05393 -0.05925 211 HIS F O     
1688 C CB    . HIS C 47 ? 0.27251 0.27820 0.33180 0.02612  -0.04934 -0.08518 211 HIS F CB    
1689 C CG    . HIS C 47 ? 0.28463 0.31269 0.33584 0.01920  -0.02488 -0.07948 211 HIS F CG    
1690 N ND1   . HIS C 47 ? 0.27979 0.33726 0.36462 -0.00113 0.00862  -0.07421 211 HIS F ND1   
1691 C CD2   . HIS C 47 ? 0.33201 0.32960 0.34306 0.00072  0.01822  -0.09439 211 HIS F CD2   
1692 C CE1   . HIS C 47 ? 0.36142 0.34147 0.32250 -0.01834 0.01582  -0.08174 211 HIS F CE1   
1693 N NE2   . HIS C 47 ? 0.37024 0.33844 0.37225 -0.01842 0.03517  -0.08652 211 HIS F NE2   
1701 N N     . ARG C 48 ? 0.25284 0.24433 0.28134 0.01908  -0.05616 0.00097  212 ARG F N     
1702 C CA    A ARG C 48 ? 0.28093 0.25499 0.29141 0.02007  -0.03100 0.01133  212 ARG F CA    
1703 C CA    B ARG C 48 ? 0.28175 0.24761 0.27307 0.02467  -0.04613 -0.00063 212 ARG F CA    
1704 C C     . ARG C 48 ? 0.26481 0.25061 0.24182 0.01316  -0.04886 0.00242  212 ARG F C     
1705 O O     . ARG C 48 ? 0.28490 0.27008 0.27286 0.03080  -0.05864 0.00944  212 ARG F O     
1706 C CB    A ARG C 48 ? 0.30322 0.27559 0.35404 -0.00270 0.01230  0.02121  212 ARG F CB    
1707 C CB    B ARG C 48 ? 0.30930 0.25783 0.31372 -0.00074 -0.02020 -0.01085 212 ARG F CB    
1708 C CG    A ARG C 48 ? 0.32354 0.29128 0.38516 -0.00640 0.05587  0.05161  212 ARG F CG    
1709 C CG    B ARG C 48 ? 0.33159 0.26404 0.31008 -0.00993 -0.00793 0.00906  212 ARG F CG    
1710 C CD    A ARG C 48 ? 0.36746 0.32030 0.44542 -0.00909 0.09532  0.05687  212 ARG F CD    
1711 C CD    B ARG C 48 ? 0.37738 0.29925 0.38876 -0.02426 0.03811  0.00870  212 ARG F CD    
1712 N NE    A ARG C 48 ? 0.38816 0.33342 0.48747 -0.00367 0.12988  0.08033  212 ARG F NE    
1713 N NE    B ARG C 48 ? 0.38925 0.31658 0.47055 -0.02150 0.08021  0.04444  212 ARG F NE    
1714 C CZ    A ARG C 48 ? 0.38641 0.34326 0.51794 0.03208  0.09456  0.10101  212 ARG F CZ    
1715 C CZ    B ARG C 48 ? 0.39677 0.31789 0.53270 0.01565  0.10903  0.10576  212 ARG F CZ    
1716 N NH1   A ARG C 48 ? 0.39810 0.35362 0.55263 0.03059  0.08421  0.08294  212 ARG F NH1   
1717 N NH1   B ARG C 48 ? 0.42042 0.33201 0.54542 0.01616  0.11391  0.11775  212 ARG F NH1   
1718 N NH2   A ARG C 48 ? 0.38140 0.33245 0.47410 0.04655  0.11623  0.15583  212 ARG F NH2   
1719 N NH2   B ARG C 48 ? 0.36301 0.30981 0.55740 0.02420  0.09360  0.11774  212 ARG F NH2   
1744 N N     . TRP C 49 ? 0.23716 0.24336 0.23691 0.01336  -0.02951 -0.00031 213 TRP F N     
1745 C CA    . TRP C 49 ? 0.22384 0.25047 0.23600 0.01480  0.00670  0.00485  213 TRP F CA    
1746 C C     . TRP C 49 ? 0.24338 0.28282 0.21917 0.03213  0.00411  -0.00129 213 TRP F C     
1747 O O     . TRP C 49 ? 0.27349 0.27503 0.21691 0.02802  -0.03647 0.01212  213 TRP F O     
1748 C CB    . TRP C 49 ? 0.20550 0.24877 0.23700 0.00833  0.00222  0.00003  213 TRP F CB    
1749 C CG    . TRP C 49 ? 0.18832 0.25307 0.21669 0.01549  -0.00362 0.00121  213 TRP F CG    
1750 C CD1   . TRP C 49 ? 0.19412 0.25208 0.21047 0.01250  -0.00763 -0.01813 213 TRP F CD1   
1751 C CD2   . TRP C 49 ? 0.17942 0.25603 0.19569 0.01726  0.00494  0.02487  213 TRP F CD2   
1752 N NE1   . TRP C 49 ? 0.17738 0.24893 0.22439 -0.01132 0.00111  -0.00562 213 TRP F NE1   
1753 C CE2   . TRP C 49 ? 0.18771 0.26814 0.19477 0.00949  -0.00085 -0.01939 213 TRP F CE2   
1754 C CE3   . TRP C 49 ? 0.19083 0.28416 0.20875 0.01124  -0.01078 0.01846  213 TRP F CE3   
1755 C CZ2   . TRP C 49 ? 0.19834 0.29039 0.22512 -0.01130 -0.01935 -0.01412 213 TRP F CZ2   
1756 C CZ3   . TRP C 49 ? 0.22269 0.29164 0.20260 -0.00041 -0.00623 -0.00436 213 TRP F CZ3   
1757 C CH2   . TRP C 49 ? 0.23467 0.29663 0.19894 -0.01234 0.02775  -0.00517 213 TRP F CH2   
1768 N N     . GLY C 50 ? 0.18963 0.31731 0.25843 0.03500  -0.03364 -0.00600 214 GLY F N     
1769 C CA    . GLY C 50 ? 0.24060 0.33815 0.30475 0.05898  0.00527  -0.00990 214 GLY F CA    
1770 C C     . GLY C 50 ? 0.30026 0.32351 0.31574 0.06617  -0.01748 -0.02760 214 GLY F C     
1771 O O     . GLY C 50 ? 0.28515 0.32076 0.34753 0.06594  -0.05431 -0.04504 214 GLY F O     
1775 N N     . ILE C 51 ? 0.30543 0.29478 0.33134 0.08014  -0.05694 -0.00896 215 ILE F N     
1776 C CA    . ILE C 51 ? 0.35346 0.30706 0.39160 0.09229  -0.06768 0.00162  215 ILE F CA    
1777 C C     . ILE C 51 ? 0.34373 0.32458 0.38465 0.08416  -0.06320 0.05185  215 ILE F C     
1778 O O     . ILE C 51 ? 0.32658 0.34518 0.41615 0.07348  -0.05857 0.04442  215 ILE F O     
1779 C CB    . ILE C 51 ? 0.38940 0.29354 0.42050 0.10076  -0.11136 -0.00306 215 ILE F CB    
1780 C CG1   . ILE C 51 ? 0.44849 0.32062 0.43303 0.08817  -0.09832 -0.04955 215 ILE F CG1   
1781 C CG2   . ILE C 51 ? 0.44172 0.27149 0.47865 0.07383  -0.06518 -0.00855 215 ILE F CG2   
1782 C CD1   . ILE C 51 ? 0.46328 0.34981 0.44045 0.04366  -0.09922 -0.09282 215 ILE F CD1   
1794 N N     . GLN C 52 ? 0.32749 0.33451 0.37046 0.06713  -0.08352 0.05965  216 GLN F N     
1795 C CA    . GLN C 52 ? 0.34622 0.36977 0.33755 0.06730  -0.02932 0.05797  216 GLN F CA    
1796 C C     . GLN C 52 ? 0.35310 0.36870 0.24973 0.03929  -0.05446 0.02966  216 GLN F C     
1797 O O     . GLN C 52 ? 0.38381 0.39846 0.25332 0.04009  -0.01981 0.02572  216 GLN F O     
1798 C CB    . GLN C 52 ? 0.35528 0.41874 0.36052 0.04936  -0.02376 0.02651  216 GLN F CB    
1799 C CG    . GLN C 52 ? 0.36424 0.45376 0.38970 0.06858  -0.02662 0.06153  216 GLN F CG    
1800 C CD    . GLN C 52 ? 0.39125 0.47435 0.46657 0.08733  0.03558  0.09231  216 GLN F CD    
1801 O OE1   . GLN C 52 ? 0.40700 0.49739 0.49262 0.08526  0.03599  0.06876  216 GLN F OE1   
1802 N NE2   . GLN C 52 ? 0.38641 0.47348 0.50609 0.08411  0.04701  0.12632  216 GLN F NE2   
1811 N N     . LYS C 53 ? 0.34799 0.34023 0.24970 0.04828  -0.05667 0.02969  217 LYS F N     
1812 C CA    . LYS C 53 ? 0.31500 0.33729 0.25442 0.05559  -0.07317 0.01360  217 LYS F CA    
1813 C C     . LYS C 53 ? 0.33720 0.35361 0.28916 0.06359  -0.08304 -0.01258 217 LYS F C     
1814 O O     . LYS C 53 ? 0.35283 0.37557 0.30802 0.07207  -0.09442 -0.01090 217 LYS F O     
1815 C CB    . LYS C 53 ? 0.30985 0.34614 0.23302 0.06693  -0.03434 0.04267  217 LYS F CB    
1816 C CG    . LYS C 53 ? 0.30977 0.35027 0.21824 0.06922  -0.00264 0.04329  217 LYS F CG    
1817 C CD    . LYS C 53 ? 0.30422 0.35529 0.19007 0.05039  -0.00225 0.02016  217 LYS F CD    
1818 C CE    . LYS C 53 ? 0.32744 0.35740 0.18106 0.04249  -0.00932 0.02562  217 LYS F CE    
1819 N NZ    . LYS C 53 ? 0.30915 0.34311 0.18041 0.02960  -0.00406 0.01256  217 LYS F NZ    
1833 N N     . GLY C 54 ? 0.33325 0.36197 0.32355 0.06100  -0.05535 -0.00334 218 GLY F N     
1834 C CA    . GLY C 54 ? 0.32333 0.38087 0.35836 0.05785  -0.03319 0.01684  218 GLY F CA    
1835 C C     . GLY C 54 ? 0.32139 0.39652 0.37896 0.04317  -0.03067 0.02636  218 GLY F C     
1836 O O     . GLY C 54 ? 0.30114 0.42364 0.40410 0.05483  -0.06556 0.05428  218 GLY F O     
1840 N N     . ASN C 55 ? 0.29948 0.37590 0.34047 0.03925  -0.06089 0.00910  219 ASN F N     
1841 C CA    . ASN C 55 ? 0.28430 0.37554 0.32318 0.06799  -0.04589 0.02057  219 ASN F CA    
1842 C C     . ASN C 55 ? 0.27421 0.38617 0.36583 0.05941  -0.03871 -0.00037 219 ASN F C     
1843 O O     . ASN C 55 ? 0.28656 0.38283 0.37522 0.06955  -0.04848 -0.00567 219 ASN F O     
1844 C CB    . ASN C 55 ? 0.30899 0.36009 0.27842 0.08091  -0.03457 0.02115  219 ASN F CB    
1845 C CG    . ASN C 55 ? 0.28405 0.34076 0.29151 0.05785  0.01291  -0.00711 219 ASN F CG    
1846 O OD1   . ASN C 55 ? 0.28452 0.35954 0.30016 0.04841  -0.01150 -0.00295 219 ASN F OD1   
1847 N ND2   . ASN C 55 ? 0.23187 0.35612 0.24629 0.03387  -0.01466 -0.00673 219 ASN F ND2   
1854 N N     . ARG C 56 ? 0.25801 0.40439 0.40289 0.05755  -0.01427 -0.00840 220 ARG F N     
1855 C CA    . ARG C 56 ? 0.27784 0.41093 0.43724 0.06552  0.00317  -0.02639 220 ARG F CA    
1856 C C     . ARG C 56 ? 0.24029 0.40429 0.43165 0.08119  -0.02215 -0.04149 220 ARG F C     
1857 O O     . ARG C 56 ? 0.29431 0.41178 0.44675 0.03953  -0.00175 -0.05631 220 ARG F O     
1858 C CB    . ARG C 56 ? 0.29274 0.43099 0.43286 0.07636  0.01292  -0.01454 220 ARG F CB    
1859 C CG    . ARG C 56 ? 0.30668 0.42860 0.45202 0.07490  -0.02243 -0.03019 220 ARG F CG    
1860 C CD    . ARG C 56 ? 0.39163 0.43042 0.44367 0.01658  -0.01836 -0.05587 220 ARG F CD    
1861 N NE    . ARG C 56 ? 0.45716 0.42681 0.45991 -0.01981 -0.03189 -0.06064 220 ARG F NE    
1862 C CZ    . ARG C 56 ? 0.53096 0.42694 0.47732 -0.03111 -0.03152 -0.05310 220 ARG F CZ    
1863 N NH1   . ARG C 56 ? 0.57124 0.42028 0.51173 -0.03241 -0.00003 -0.04804 220 ARG F NH1   
1864 N NH2   . ARG C 56 ? 0.53815 0.43418 0.47528 -0.02241 -0.06494 -0.04200 220 ARG F NH2   
1878 N N     . LYS C 57 ? 0.21153 0.40124 0.45994 0.06628  -0.03236 -0.07251 221 LYS F N     
1879 C CA    . LYS C 57 ? 0.23298 0.38123 0.43564 0.06261  0.00317  -0.08048 221 LYS F CA    
1880 C C     . LYS C 57 ? 0.23916 0.36135 0.39876 0.08263  -0.00233 -0.07034 221 LYS F C     
1881 O O     . LYS C 57 ? 0.25541 0.33203 0.39605 0.07501  0.02220  -0.04739 221 LYS F O     
1882 C CB    . LYS C 57 ? 0.25184 0.42808 0.54816 0.00994  0.04699  -0.10181 221 LYS F CB    
1883 C CG    . LYS C 57 ? 0.28386 0.46227 0.65885 0.02914  0.06435  -0.06865 221 LYS F CG    
1884 C CD    . LYS C 57 ? 0.37411 0.49286 0.82535 0.05362  0.24288  -0.02410 221 LYS F CD    
1885 C CE    . LYS C 57 ? 0.47449 0.51661 0.92881 0.05566  0.34617  0.01209  221 LYS F CE    
1886 N NZ    . LYS C 57 ? 0.55825 0.52905 0.98974 0.07462  0.35453  0.02273  221 LYS F NZ    
1900 N N     . LYS C 58 ? 0.25182 0.39939 0.36048 0.07892  -0.04088 -0.09984 222 LYS F N     
1901 C CA    . LYS C 58 ? 0.26001 0.44005 0.36083 0.07100  -0.02326 -0.10462 222 LYS F CA    
1902 C C     . LYS C 58 ? 0.22635 0.39886 0.32731 0.04742  -0.00023 -0.08778 222 LYS F C     
1903 O O     . LYS C 58 ? 0.22092 0.39729 0.34018 0.04172  -0.00849 -0.09089 222 LYS F O     
1904 C CB    . LYS C 58 ? 0.30981 0.51955 0.39510 0.06739  -0.04647 -0.14376 222 LYS F CB    
1905 C CG    . LYS C 58 ? 0.45012 0.60536 0.43908 0.05992  0.00606  -0.17928 222 LYS F CG    
1906 C CD    . LYS C 58 ? 0.60185 0.69251 0.46723 0.04685  0.05199  -0.18265 222 LYS F CD    
1907 C CE    . LYS C 58 ? 0.72881 0.75341 0.52392 0.05190  0.12229  -0.17321 222 LYS F CE    
1908 N NZ    . LYS C 58 ? 0.77345 0.79364 0.57582 0.05601  0.17097  -0.14732 222 LYS F NZ    
1922 N N     . MET C 59 ? 0.19188 0.35004 0.29303 0.01883  0.01034  -0.09811 223 MET F N     
1923 C CA    . MET C 59 ? 0.19679 0.33356 0.28076 0.01120  0.02358  -0.10466 223 MET F CA    
1924 C C     . MET C 59 ? 0.25275 0.34143 0.27846 -0.00308 -0.00503 -0.12209 223 MET F C     
1925 O O     . MET C 59 ? 0.31282 0.33703 0.37107 0.01069  -0.04326 -0.09243 223 MET F O     
1926 C CB    . MET C 59 ? 0.22646 0.31216 0.27017 -0.00045 0.04856  -0.08292 223 MET F CB    
1927 C CG    . MET C 59 ? 0.22793 0.32147 0.25544 0.01724  0.06820  -0.04585 223 MET F CG    
1928 S SD    . MET C 59 ? 0.19557 0.33910 0.22469 -0.00616 0.00155  -0.04815 223 MET F SD    
1929 C CE    . MET C 59 ? 0.18987 0.34371 0.20554 0.00545  0.00452  -0.00852 223 MET F CE    
1939 N N     . THR C 60 ? 0.19959 0.37528 0.24787 0.01138  -0.00194 -0.08756 224 THR F N     
1940 C CA    . THR C 60 ? 0.21994 0.38525 0.23576 -0.02339 0.00179  -0.08082 224 THR F CA    
1941 C C     . THR C 60 ? 0.22057 0.35134 0.19379 -0.03213 -0.00921 -0.05683 224 THR F C     
1942 O O     . THR C 60 ? 0.20677 0.34312 0.17630 -0.00999 -0.02112 -0.04186 224 THR F O     
1943 C CB    . THR C 60 ? 0.25143 0.41606 0.22425 -0.00745 -0.00686 -0.08926 224 THR F CB    
1944 O OG1   . THR C 60 ? 0.26653 0.42755 0.21258 -0.00313 -0.00111 -0.09390 224 THR F OG1   
1945 C CG2   . THR C 60 ? 0.24954 0.44641 0.26071 -0.00042 -0.02142 -0.09690 224 THR F CG2   
1953 N N     . TYR C 61 ? 0.22301 0.31759 0.20276 -0.03809 -0.03552 -0.02172 225 TYR F N     
1954 C CA    . TYR C 61 ? 0.20159 0.31376 0.17753 -0.04705 -0.02132 -0.02062 225 TYR F CA    
1955 C C     . TYR C 61 ? 0.22556 0.31770 0.15813 -0.05199 -0.00442 -0.01582 225 TYR F C     
1956 O O     . TYR C 61 ? 0.24955 0.32187 0.18597 -0.04165 -0.03303 -0.03438 225 TYR F O     
1957 C CB    . TYR C 61 ? 0.23736 0.29627 0.21821 -0.02678 -0.00681 -0.04048 225 TYR F CB    
1958 C CG    . TYR C 61 ? 0.21146 0.32337 0.22591 -0.03945 -0.01336 -0.05303 225 TYR F CG    
1959 C CD1   . TYR C 61 ? 0.18826 0.34044 0.20854 -0.03960 -0.02482 -0.03128 225 TYR F CD1   
1960 C CD2   . TYR C 61 ? 0.21622 0.33279 0.19232 -0.03405 -0.01736 -0.03980 225 TYR F CD2   
1961 C CE1   . TYR C 61 ? 0.22224 0.35199 0.20036 0.00088  -0.02332 -0.03446 225 TYR F CE1   
1962 C CE2   . TYR C 61 ? 0.23018 0.34108 0.21296 -0.03260 -0.02628 -0.04466 225 TYR F CE2   
1963 C CZ    . TYR C 61 ? 0.21128 0.34958 0.21390 0.01135  -0.03864 -0.02065 225 TYR F CZ    
1964 O OH    . TYR C 61 ? 0.26565 0.36695 0.23066 0.03536  -0.03937 -0.01781 225 TYR F OH    
1974 N N     . GLN C 62 ? 0.27615 0.35515 0.17729 -0.06045 0.00960  -0.00987 226 GLN F N     
1975 C CA    A GLN C 62 ? 0.26890 0.36832 0.15316 -0.04627 -0.03444 0.02246  226 GLN F CA    
1976 C CA    B GLN C 62 ? 0.27163 0.36123 0.20771 -0.06558 0.00824  0.00619  226 GLN F CA    
1977 C C     . GLN C 62 ? 0.27310 0.37113 0.16513 -0.05666 0.00077  -0.00402 226 GLN F C     
1978 O O     . GLN C 62 ? 0.25086 0.36849 0.22649 -0.06037 -0.04196 -0.00810 226 GLN F O     
1979 C CB    A GLN C 62 ? 0.30495 0.40158 0.15705 -0.04244 -0.03284 0.03707  226 GLN F CB    
1980 C CB    B GLN C 62 ? 0.29590 0.37348 0.29249 -0.07506 0.02798  0.00995  226 GLN F CB    
1981 C CG    A GLN C 62 ? 0.33128 0.42056 0.17714 -0.00007 -0.04606 0.05559  226 GLN F CG    
1982 C CG    B GLN C 62 ? 0.33999 0.37707 0.32137 -0.04383 0.04404  0.01428  226 GLN F CG    
1983 C CD    A GLN C 62 ? 0.34124 0.43046 0.24066 0.01113  -0.07553 0.06271  226 GLN F CD    
1984 C CD    B GLN C 62 ? 0.30975 0.38226 0.30900 -0.01280 0.00364  0.02948  226 GLN F CD    
1985 O OE1   A GLN C 62 ? 0.31730 0.42575 0.25113 0.01417  -0.08550 0.03274  226 GLN F OE1   
1986 O OE1   B GLN C 62 ? 0.27425 0.35654 0.24171 -0.02336 -0.04649 0.02121  226 GLN F OE1   
1987 N NE2   A GLN C 62 ? 0.33593 0.43338 0.31527 0.01743  -0.05415 0.07771  226 GLN F NE2   
1988 N NE2   B GLN C 62 ? 0.29235 0.37892 0.28076 0.02519  0.00612  0.04121  226 GLN F NE2   
2004 N N     . LYS C 63 ? 0.21026 0.38838 0.20071 -0.07008 0.02228  -0.02532 227 LYS F N     
2005 C CA    . LYS C 63 ? 0.18992 0.38792 0.20089 -0.07490 0.01085  -0.04898 227 LYS F CA    
2006 C C     . LYS C 63 ? 0.19364 0.34472 0.17333 -0.04820 0.00491  -0.01566 227 LYS F C     
2007 O O     . LYS C 63 ? 0.21105 0.35666 0.16724 -0.06113 -0.01349 0.00311  227 LYS F O     
2008 C CB    . LYS C 63 ? 0.20163 0.41415 0.20785 -0.03806 0.03214  -0.01920 227 LYS F CB    
2009 C CG    . LYS C 63 ? 0.20609 0.43489 0.23632 -0.04238 0.03237  -0.05575 227 LYS F CG    
2010 C CD    . LYS C 63 ? 0.23390 0.44249 0.23308 -0.01860 0.01937  -0.07585 227 LYS F CD    
2011 C CE    . LYS C 63 ? 0.20053 0.45118 0.25572 -0.02650 0.01887  -0.10976 227 LYS F CE    
2012 N NZ    . LYS C 63 ? 0.18291 0.45341 0.28766 0.00277  -0.01755 -0.09847 227 LYS F NZ    
2026 N N     . MET C 64 ? 0.19310 0.30939 0.16675 -0.04296 0.00836  -0.01201 228 MET F N     
2027 C CA    . MET C 64 ? 0.17895 0.28734 0.18478 -0.03901 0.00528  -0.00472 228 MET F CA    
2028 C C     . MET C 64 ? 0.19644 0.27292 0.18417 -0.03352 -0.02166 -0.01529 228 MET F C     
2029 O O     . MET C 64 ? 0.22199 0.28063 0.17122 -0.04044 -0.02935 -0.01262 228 MET F O     
2030 C CB    . MET C 64 ? 0.16776 0.30012 0.16021 -0.01216 0.00376  -0.03016 228 MET F CB    
2031 C CG    . MET C 64 ? 0.20281 0.28953 0.19131 -0.00878 0.03849  0.02127  228 MET F CG    
2032 S SD    . MET C 64 ? 0.21634 0.27765 0.20598 -0.02151 0.00509  -0.01023 228 MET F SD    
2033 C CE    . MET C 64 ? 0.22104 0.33270 0.30130 -0.01793 -0.01449 0.00980  228 MET F CE    
2043 N N     . ALA C 65 ? 0.21153 0.27903 0.18990 -0.05482 -0.05250 -0.00312 229 ALA F N     
2044 C CA    . ALA C 65 ? 0.25312 0.30272 0.18982 -0.07289 -0.05771 0.03503  229 ALA F CA    
2045 C C     . ALA C 65 ? 0.26247 0.29062 0.19340 -0.08734 -0.06403 0.05496  229 ALA F C     
2046 O O     . ALA C 65 ? 0.28255 0.31640 0.22508 -0.05880 -0.06689 0.01002  229 ALA F O     
2047 C CB    . ALA C 65 ? 0.27342 0.32181 0.19968 -0.03728 -0.09171 0.02407  229 ALA F CB    
2053 N N     . ARG C 66 ? 0.26310 0.30106 0.19848 -0.09058 -0.07994 0.05566  230 ARG F N     
2054 C CA    . ARG C 66 ? 0.28247 0.31175 0.19228 -0.11196 -0.04631 0.04077  230 ARG F CA    
2055 C C     . ARG C 66 ? 0.28233 0.28808 0.18387 -0.09719 -0.05904 0.01880  230 ARG F C     
2056 O O     . ARG C 66 ? 0.32376 0.32005 0.22770 -0.10718 -0.09590 0.04022  230 ARG F O     
2057 C CB    . ARG C 66 ? 0.31380 0.32997 0.22023 -0.13727 -0.00862 0.04021  230 ARG F CB    
2058 C CG    . ARG C 66 ? 0.39145 0.34544 0.30507 -0.13675 0.02910  0.00430  230 ARG F CG    
2059 C CD    . ARG C 66 ? 0.34616 0.32143 0.23827 -0.08619 0.00341  0.00490  230 ARG F CD    
2060 N NE    . ARG C 66 ? 0.27165 0.29246 0.19038 -0.06936 -0.05901 0.03517  230 ARG F NE    
2061 C CZ    . ARG C 66 ? 0.32273 0.34047 0.23880 0.01274  0.00938  -0.01600 230 ARG F CZ    
2062 N NH1   . ARG C 66 ? 0.28238 0.31599 0.16969 0.03418  -0.08069 -0.01102 230 ARG F NH1   
2063 N NH2   . ARG C 66 ? 0.31399 0.40510 0.25590 0.04641  -0.07369 -0.01713 230 ARG F NH2   
2077 N N     . ALA C 67 ? 0.24245 0.28553 0.20362 -0.08150 -0.05149 0.02431  231 ALA F N     
2078 C CA    . ALA C 67 ? 0.25630 0.27644 0.20300 -0.08118 -0.04568 0.00712  231 ALA F CA    
2079 C C     . ALA C 67 ? 0.26984 0.27380 0.18202 -0.07066 -0.06455 0.00550  231 ALA F C     
2080 O O     . ALA C 67 ? 0.31219 0.30195 0.22301 -0.07400 -0.06501 -0.01411 231 ALA F O     
2081 C CB    . ALA C 67 ? 0.24879 0.27873 0.20460 -0.03866 -0.03073 0.03206  231 ALA F CB    
2087 N N     . LEU C 68 ? 0.26001 0.27433 0.19116 -0.07387 -0.03507 0.00908  232 LEU F N     
2088 C CA    . LEU C 68 ? 0.22366 0.27152 0.24845 -0.07239 -0.02853 0.00711  232 LEU F CA    
2089 C C     . LEU C 68 ? 0.26183 0.27533 0.24821 -0.03508 -0.02247 0.00677  232 LEU F C     
2090 O O     . LEU C 68 ? 0.29837 0.28631 0.29396 -0.02022 -0.01796 -0.03045 232 LEU F O     
2091 C CB    . LEU C 68 ? 0.24237 0.27768 0.22339 -0.04559 -0.02440 0.01408  232 LEU F CB    
2092 C CG    . LEU C 68 ? 0.25358 0.26568 0.23722 -0.05953 -0.05429 0.01187  232 LEU F CG    
2093 C CD1   . LEU C 68 ? 0.30045 0.25247 0.26337 -0.04448 -0.05089 0.02441  232 LEU F CD1   
2094 C CD2   . LEU C 68 ? 0.28542 0.27294 0.25695 -0.04673 -0.01619 0.04436  232 LEU F CD2   
2106 N N     . ARG C 69 ? 0.31485 0.28773 0.25811 -0.04816 -0.05818 0.00794  233 ARG F N     
2107 C CA    . ARG C 69 ? 0.35385 0.30709 0.25640 -0.04385 -0.03806 0.00720  233 ARG F CA    
2108 C C     . ARG C 69 ? 0.33046 0.27355 0.28439 -0.05794 -0.04838 0.00157  233 ARG F C     
2109 O O     . ARG C 69 ? 0.37254 0.27526 0.31587 -0.03985 -0.05345 0.00074  233 ARG F O     
2110 C CB    . ARG C 69 ? 0.37929 0.35237 0.25347 -0.05368 -0.03883 -0.00088 233 ARG F CB    
2111 C CG    . ARG C 69 ? 0.38454 0.40280 0.27327 -0.03763 -0.05611 0.03686  233 ARG F CG    
2112 C CD    . ARG C 69 ? 0.39028 0.44950 0.26760 -0.01708 -0.04118 0.08056  233 ARG F CD    
2113 N NE    . ARG C 69 ? 0.38914 0.49171 0.26922 -0.03976 -0.05069 0.09481  233 ARG F NE    
2114 C CZ    . ARG C 69 ? 0.35753 0.50818 0.26434 -0.02610 -0.09281 0.11554  233 ARG F CZ    
2115 N NH1   . ARG C 69 ? 0.29935 0.51332 0.27608 -0.01834 -0.07745 0.09283  233 ARG F NH1   
2116 N NH2   . ARG C 69 ? 0.38648 0.52613 0.29017 -0.04729 -0.09233 0.17585  233 ARG F NH2   
2130 N N     . ASN C 70 ? 0.31291 0.26303 0.26993 -0.07941 -0.01152 0.00127  234 ASN F N     
2131 C CA    . ASN C 70 ? 0.29558 0.28106 0.29947 -0.05379 -0.00017 -0.01551 234 ASN F CA    
2132 C C     . ASN C 70 ? 0.35762 0.28930 0.29343 -0.04000 0.03424  -0.01335 234 ASN F C     
2133 O O     . ASN C 70 ? 0.38935 0.28998 0.36538 -0.06628 0.06273  -0.04119 234 ASN F O     
2134 C CB    . ASN C 70 ? 0.27116 0.28986 0.31207 -0.04648 -0.00743 -0.01057 234 ASN F CB    
2135 C CG    . ASN C 70 ? 0.27272 0.29119 0.33138 -0.03204 0.02190  -0.01453 234 ASN F CG    
2136 O OD1   . ASN C 70 ? 0.29839 0.30827 0.36119 0.02083  0.03776  0.01398  234 ASN F OD1   
2137 N ND2   . ASN C 70 ? 0.27779 0.28538 0.32377 -0.03343 -0.01585 -0.04558 234 ASN F ND2   
2144 N N     . TYR C 71 ? 0.28105 0.28216 0.25566 -0.01155 -0.02777 -0.01136 235 TYR F N     
2145 C CA    . TYR C 71 ? 0.25342 0.30431 0.29717 -0.01010 -0.02378 -0.01246 235 TYR F CA    
2146 C C     . TYR C 71 ? 0.31399 0.30484 0.41031 -0.00952 0.02785  -0.01640 235 TYR F C     
2147 O O     . TYR C 71 ? 0.31309 0.30435 0.42076 0.01516  0.03285  -0.05106 235 TYR F O     
2148 C CB    . TYR C 71 ? 0.24663 0.33267 0.27178 0.00079  -0.01916 0.01881  235 TYR F CB    
2149 C CG    . TYR C 71 ? 0.22429 0.32454 0.22724 -0.00065 -0.01686 0.02950  235 TYR F CG    
2150 C CD1   . TYR C 71 ? 0.26201 0.31763 0.25695 -0.00968 -0.04731 -0.00568 235 TYR F CD1   
2151 C CD2   . TYR C 71 ? 0.17310 0.32123 0.24829 -0.01271 -0.01912 0.00408  235 TYR F CD2   
2152 C CE1   . TYR C 71 ? 0.24856 0.30708 0.24214 -0.00974 -0.05075 -0.01431 235 TYR F CE1   
2153 C CE2   . TYR C 71 ? 0.17565 0.31100 0.21751 -0.00427 -0.01763 -0.00505 235 TYR F CE2   
2154 C CZ    . TYR C 71 ? 0.18616 0.30540 0.23636 0.00456  -0.03245 0.00161  235 TYR F CZ    
2155 O OH    . TYR C 71 ? 0.18831 0.31854 0.21371 -0.00592 -0.02804 -0.02419 235 TYR F OH    
2165 N N     . GLY C 72 ? 0.37932 0.31166 0.45934 0.05101  -0.01083 0.01759  236 GLY F N     
2166 C CA    . GLY C 72 ? 0.43823 0.31067 0.52540 0.06791  -0.01437 0.01545  236 GLY F CA    
2167 C C     . GLY C 72 ? 0.50367 0.31789 0.60388 0.05388  0.01668  0.00290  236 GLY F C     
2168 O O     . GLY C 72 ? 0.54854 0.31044 0.69233 0.04407  0.05036  -0.01616 236 GLY F O     
2172 N N     . LYS C 73 ? 0.55908 0.34825 0.60262 0.01223  0.03395  -0.00972 237 LYS F N     
2173 C CA    . LYS C 73 ? 0.60329 0.39293 0.61890 -0.04432 0.05060  -0.05307 237 LYS F CA    
2174 C C     . LYS C 73 ? 0.64574 0.39526 0.56185 -0.05756 0.07528  -0.06730 237 LYS F C     
2175 O O     . LYS C 73 ? 0.75477 0.41464 0.55063 -0.05131 0.19217  -0.05266 237 LYS F O     
2176 C CB    . LYS C 73 ? 0.61363 0.42773 0.68835 -0.05095 0.01385  -0.07769 237 LYS F CB    
2177 C CG    . LYS C 73 ? 0.61914 0.45417 0.76137 -0.05837 -0.02252 -0.11429 237 LYS F CG    
2178 C CD    . LYS C 73 ? 0.61359 0.46695 0.80139 -0.07291 -0.05570 -0.14754 237 LYS F CD    
2179 C CE    . LYS C 73 ? 0.61237 0.48092 0.82155 -0.07845 -0.08200 -0.16350 237 LYS F CE    
2180 N NZ    . LYS C 73 ? 0.62183 0.48606 0.84274 -0.07376 -0.07784 -0.16032 237 LYS F NZ    
2194 N N     . THR C 74 ? 0.53992 0.38874 0.51527 -0.11603 -0.03206 -0.09243 238 THR F N     
2195 C CA    . THR C 74 ? 0.47288 0.39863 0.52861 -0.09995 -0.06320 -0.10648 238 THR F CA    
2196 C C     . THR C 74 ? 0.44555 0.41204 0.50010 -0.07824 -0.02084 -0.10300 238 THR F C     
2197 O O     . THR C 74 ? 0.47336 0.44177 0.53229 -0.08309 0.00445  -0.09011 238 THR F O     
2198 C CB    . THR C 74 ? 0.43650 0.40803 0.56195 -0.08339 -0.11861 -0.08458 238 THR F CB    
2199 O OG1   . THR C 74 ? 0.42706 0.43253 0.54290 -0.05791 -0.14594 -0.05835 238 THR F OG1   
2200 C CG2   . THR C 74 ? 0.44868 0.41714 0.61668 -0.06056 -0.10469 -0.09792 238 THR F CG2   
2208 N N     . GLY C 75 ? 0.40713 0.39608 0.44975 -0.08508 -0.00524 -0.10843 239 GLY F N     
2209 C CA    . GLY C 75 ? 0.36916 0.39288 0.44982 -0.06463 0.03024  -0.04771 239 GLY F CA    
2210 C C     . GLY C 75 ? 0.32536 0.37960 0.39653 -0.05078 -0.02286 -0.03127 239 GLY F C     
2211 O O     . GLY C 75 ? 0.31317 0.38697 0.41802 -0.00725 0.02234  0.00863  239 GLY F O     
2215 N N     . GLU C 76 ? 0.28905 0.36551 0.35068 -0.03743 -0.04322 -0.05349 240 GLU F N     
2216 C CA    . GLU C 76 ? 0.29519 0.36331 0.30296 -0.03927 -0.02139 -0.07054 240 GLU F CA    
2217 C C     . GLU C 76 ? 0.22463 0.36388 0.27100 -0.01517 -0.02341 -0.05679 240 GLU F C     
2218 O O     . GLU C 76 ? 0.23829 0.38114 0.25199 -0.00787 -0.00848 -0.05648 240 GLU F O     
2219 C CB    . GLU C 76 ? 0.25741 0.36033 0.31838 -0.02756 -0.06812 -0.06140 240 GLU F CB    
2220 C CG    . GLU C 76 ? 0.28214 0.36634 0.34008 -0.04391 -0.07581 -0.09006 240 GLU F CG    
2221 C CD    . GLU C 76 ? 0.31155 0.39015 0.43884 -0.03579 -0.10892 -0.08483 240 GLU F CD    
2222 O OE1   . GLU C 76 ? 0.29474 0.38165 0.40664 -0.05136 -0.09178 -0.06191 240 GLU F OE1   
2223 O OE2   . GLU C 76 ? 0.34494 0.41490 0.51484 -0.05818 -0.12908 -0.09165 240 GLU F OE2   
2230 N N     . VAL C 77 ? 0.23881 0.35209 0.23588 -0.02950 -0.02058 -0.03248 241 VAL F N     
2231 C CA    . VAL C 77 ? 0.22496 0.34172 0.24949 -0.03425 -0.01650 -0.02580 241 VAL F CA    
2232 C C     . VAL C 77 ? 0.26001 0.33481 0.29786 -0.04779 0.00250  -0.02353 241 VAL F C     
2233 O O     . VAL C 77 ? 0.26424 0.33145 0.31750 -0.05498 0.00128  -0.01614 241 VAL F O     
2234 C CB    . VAL C 77 ? 0.19953 0.34674 0.23683 -0.02257 -0.02961 -0.01404 241 VAL F CB    
2235 C CG1   . VAL C 77 ? 0.25888 0.34762 0.25205 -0.01221 -0.02484 -0.00684 241 VAL F CG1   
2236 C CG2   . VAL C 77 ? 0.24510 0.35522 0.23205 -0.01733 -0.02318 0.01048  241 VAL F CG2   
2246 N N     . LYS C 78 ? 0.27043 0.33210 0.26508 -0.04683 -0.02769 -0.00480 242 LYS F N     
2247 C CA    . LYS C 78 ? 0.32330 0.32334 0.23558 -0.00657 -0.06011 -0.00302 242 LYS F CA    
2248 C C     . LYS C 78 ? 0.26046 0.31098 0.22525 -0.04295 -0.05333 -0.01842 242 LYS F C     
2249 O O     . LYS C 78 ? 0.26469 0.32298 0.22538 -0.05625 -0.01805 -0.01767 242 LYS F O     
2250 C CB    . LYS C 78 ? 0.44564 0.34459 0.33386 0.03099  -0.03260 -0.03040 242 LYS F CB    
2251 C CG    . LYS C 78 ? 0.56465 0.39696 0.47956 0.06232  0.00798  -0.05412 242 LYS F CG    
2252 C CD    . LYS C 78 ? 0.66990 0.43000 0.63357 0.08781  0.08002  -0.07045 242 LYS F CD    
2253 C CE    . LYS C 78 ? 0.75668 0.47037 0.72183 0.09906  0.14482  -0.08298 242 LYS F CE    
2254 N NZ    . LYS C 78 ? 0.79865 0.50563 0.79199 0.10215  0.19029  -0.10779 242 LYS F NZ    
2268 N N     . LYS C 79 ? 0.27723 0.32189 0.26987 -0.02766 -0.02139 0.03167  243 LYS F N     
2269 C CA    . LYS C 79 ? 0.25045 0.31933 0.24309 -0.03206 -0.03924 0.02359  243 LYS F CA    
2270 C C     . LYS C 79 ? 0.26001 0.31492 0.28094 -0.01737 -0.03993 0.03559  243 LYS F C     
2271 O O     . LYS C 79 ? 0.30721 0.31857 0.36557 -0.00753 -0.03299 -0.01236 243 LYS F O     
2272 C CB    . LYS C 79 ? 0.28158 0.33054 0.25276 -0.03256 -0.04096 0.00842  243 LYS F CB    
2273 C CG    . LYS C 79 ? 0.31260 0.33468 0.24179 -0.02319 -0.01235 0.03272  243 LYS F CG    
2274 C CD    . LYS C 79 ? 0.30794 0.34413 0.22187 -0.02530 0.00061  0.03562  243 LYS F CD    
2275 C CE    . LYS C 79 ? 0.27377 0.35853 0.27101 -0.01647 0.01489  0.00012  243 LYS F CE    
2276 N NZ    . LYS C 79 ? 0.27827 0.38092 0.29197 -0.02227 -0.03501 -0.02991 243 LYS F NZ    
2290 N N     . VAL C 80 ? 0.24133 0.30787 0.28683 -0.00307 -0.03488 0.03270  244 VAL F N     
2291 C CA    . VAL C 80 ? 0.25403 0.37072 0.30270 0.00124  -0.03592 0.06363  244 VAL F CA    
2292 C C     . VAL C 80 ? 0.28232 0.35905 0.27754 -0.00736 -0.06563 0.06169  244 VAL F C     
2293 O O     . VAL C 80 ? 0.28750 0.33389 0.30272 -0.01900 -0.02299 0.03412  244 VAL F O     
2294 C CB    . VAL C 80 ? 0.24026 0.43980 0.32155 0.02182  -0.01278 0.10798  244 VAL F CB    
2295 C CG1   . VAL C 80 ? 0.23442 0.45910 0.38112 0.00874  0.02868  0.08950  244 VAL F CG1   
2296 C CG2   . VAL C 80 ? 0.26363 0.48549 0.37379 0.02648  0.07358  0.09573  244 VAL F CG2   
2306 N N     . LYS C 81 ? 0.37656 0.40102 0.33968 0.03384  -0.06699 0.07119  245 LYS F N     
2307 C CA    . LYS C 81 ? 0.42582 0.43025 0.36727 0.02949  -0.09533 0.11077  245 LYS F CA    
2308 C C     . LYS C 81 ? 0.39340 0.42571 0.39059 0.03021  -0.14669 0.08749  245 LYS F C     
2309 O O     . LYS C 81 ? 0.44451 0.41690 0.43860 0.04629  -0.12781 0.08629  245 LYS F O     
2310 C CB    . LYS C 81 ? 0.51513 0.48331 0.41605 0.00337  -0.08092 0.14729  245 LYS F CB    
2311 C CG    . LYS C 81 ? 0.61491 0.56771 0.53311 -0.03888 0.02501  0.13761  245 LYS F CG    
2312 C CD    . LYS C 81 ? 0.66924 0.63492 0.60195 -0.06302 0.05130  0.13146  245 LYS F CD    
2313 C CE    . LYS C 81 ? 0.71836 0.67846 0.65828 -0.08207 0.07887  0.13870  245 LYS F CE    
2314 N NZ    . LYS C 81 ? 0.73587 0.69461 0.67478 -0.08910 0.08049  0.13653  245 LYS F NZ    
2328 N N     . LYS C 82 ? 0.35009 0.41804 0.39966 0.00631  -0.15323 0.04665  246 LYS F N     
2329 C CA    . LYS C 82 ? 0.36447 0.43541 0.40161 0.03433  -0.16064 0.03289  246 LYS F CA    
2330 C C     . LYS C 82 ? 0.36252 0.39249 0.32816 0.01123  -0.11173 0.02824  246 LYS F C     
2331 O O     . LYS C 82 ? 0.33630 0.37261 0.30652 -0.03669 -0.09735 0.01262  246 LYS F O     
2332 C CB    . LYS C 82 ? 0.36931 0.49180 0.50869 0.07657  -0.15163 0.06647  246 LYS F CB    
2333 C CG    . LYS C 82 ? 0.44583 0.53948 0.56003 0.07603  -0.17515 0.09472  246 LYS F CG    
2334 C CD    . LYS C 82 ? 0.52004 0.58370 0.68223 0.03867  -0.09979 0.04583  246 LYS F CD    
2335 C CE    . LYS C 82 ? 0.57959 0.61263 0.78511 0.02157  -0.07318 0.03146  246 LYS F CE    
2336 N NZ    . LYS C 82 ? 0.62402 0.63226 0.85241 -0.00138 -0.03096 0.01652  246 LYS F NZ    
2350 N N     . LYS C 83 ? 0.39283 0.39341 0.31276 0.02457  -0.07849 0.03488  247 LYS F N     
2351 C CA    . LYS C 83 ? 0.40054 0.40460 0.24955 0.03100  -0.04856 0.04010  247 LYS F CA    
2352 C C     . LYS C 83 ? 0.33525 0.37846 0.24724 0.01987  -0.01647 0.01731  247 LYS F C     
2353 O O     . LYS C 83 ? 0.28244 0.37706 0.27595 0.00975  -0.05456 -0.00426 247 LYS F O     
2354 C CB    . LYS C 83 ? 0.45369 0.44812 0.28862 0.01731  -0.04610 0.02064  247 LYS F CB    
2355 C CG    . LYS C 83 ? 0.46188 0.48073 0.29503 0.05207  -0.07933 0.01006  247 LYS F CG    
2356 C CD    . LYS C 83 ? 0.47732 0.50983 0.32687 0.05244  -0.08579 -0.00692 247 LYS F CD    
2357 C CE    . LYS C 83 ? 0.48845 0.52607 0.38298 0.06320  -0.07881 0.00864  247 LYS F CE    
2358 N NZ    . LYS C 83 ? 0.49377 0.53584 0.40824 0.06955  -0.08262 0.01756  247 LYS F NZ    
2372 N N     . LEU C 84 ? 0.27326 0.35964 0.24097 0.00813  0.02918  0.00517  248 LEU F N     
2373 C CA    . LEU C 84 ? 0.23276 0.33175 0.22979 0.00682  0.01065  0.00152  248 LEU F CA    
2374 C C     . LEU C 84 ? 0.19976 0.29355 0.22109 -0.01417 0.00479  -0.00176 248 LEU F C     
2375 O O     . LEU C 84 ? 0.20828 0.26854 0.21744 -0.00564 0.00680  -0.00670 248 LEU F O     
2376 C CB    . LEU C 84 ? 0.26363 0.34536 0.22934 0.00021  0.02979  -0.01782 248 LEU F CB    
2377 C CG    . LEU C 84 ? 0.22032 0.35336 0.21029 -0.01383 -0.00622 -0.01325 248 LEU F CG    
2378 C CD1   . LEU C 84 ? 0.24285 0.36066 0.24691 -0.00212 -0.00089 -0.04552 248 LEU F CD1   
2379 C CD2   . LEU C 84 ? 0.23904 0.35205 0.25926 0.01564  0.00879  -0.01141 248 LEU F CD2   
2391 N N     . THR C 85 ? 0.20360 0.28088 0.24620 0.00044  0.01779  -0.00177 249 THR F N     
2392 C CA    . THR C 85 ? 0.16601 0.27407 0.25946 0.00310  -0.01435 -0.02441 249 THR F CA    
2393 C C     . THR C 85 ? 0.18751 0.26775 0.22868 0.00934  -0.04868 0.00543  249 THR F C     
2394 O O     . THR C 85 ? 0.24160 0.25732 0.21653 -0.01047 -0.00981 0.00237  249 THR F O     
2395 C CB    . THR C 85 ? 0.20504 0.30979 0.26302 -0.00585 -0.01372 -0.03419 249 THR F CB    
2396 O OG1   . THR C 85 ? 0.23001 0.32236 0.26502 -0.00300 -0.04965 -0.03553 249 THR F OG1   
2397 C CG2   . THR C 85 ? 0.18506 0.33667 0.27239 -0.00083 -0.04509 -0.02397 249 THR F CG2   
2405 N N     . TYR C 86 ? 0.21020 0.26575 0.20396 0.00059  -0.03024 -0.00243 250 TYR F N     
2406 C CA    . TYR C 86 ? 0.21801 0.26240 0.19078 -0.00554 -0.01034 0.00371  250 TYR F CA    
2407 C C     . TYR C 86 ? 0.20414 0.27168 0.21950 -0.00798 -0.00920 -0.01772 250 TYR F C     
2408 O O     . TYR C 86 ? 0.21796 0.26519 0.24635 -0.03051 -0.01370 -0.01850 250 TYR F O     
2409 C CB    . TYR C 86 ? 0.23680 0.26421 0.18716 -0.01590 -0.02913 0.02358  250 TYR F CB    
2410 C CG    . TYR C 86 ? 0.22690 0.28309 0.19319 -0.01163 -0.02837 -0.00119 250 TYR F CG    
2411 C CD1   . TYR C 86 ? 0.20500 0.29501 0.22261 -0.03007 -0.03997 0.00536  250 TYR F CD1   
2412 C CD2   . TYR C 86 ? 0.28141 0.27689 0.18607 -0.03251 -0.01586 -0.02683 250 TYR F CD2   
2413 C CE1   . TYR C 86 ? 0.19684 0.32650 0.26770 0.01295  -0.03904 0.01157  250 TYR F CE1   
2414 C CE2   . TYR C 86 ? 0.24180 0.29516 0.22657 -0.02896 -0.01187 -0.01078 250 TYR F CE2   
2415 C CZ    . TYR C 86 ? 0.19764 0.32626 0.25614 -0.03229 -0.03523 -0.01340 250 TYR F CZ    
2416 O OH    . TYR C 86 ? 0.24032 0.34836 0.28279 -0.01517 -0.01386 0.00646  250 TYR F OH    
2426 N N     . GLN C 87 ? 0.21481 0.27003 0.24200 -0.02230 -0.00762 -0.02183 251 GLN F N     
2427 C CA    . GLN C 87 ? 0.19808 0.28533 0.23744 -0.00569 -0.01647 -0.02298 251 GLN F CA    
2428 C C     . GLN C 87 ? 0.19973 0.28475 0.24377 -0.01103 -0.00744 -0.02904 251 GLN F C     
2429 O O     . GLN C 87 ? 0.23317 0.29952 0.30049 -0.06067 -0.01405 -0.02631 251 GLN F O     
2430 C CB    . GLN C 87 ? 0.22812 0.30034 0.27864 0.02775  0.01935  -0.02967 251 GLN F CB    
2431 C CG    . GLN C 87 ? 0.27238 0.31273 0.29710 0.04530  -0.03390 -0.05099 251 GLN F CG    
2432 C CD    . GLN C 87 ? 0.31040 0.32112 0.41311 0.05923  -0.01991 -0.04525 251 GLN F CD    
2433 O OE1   . GLN C 87 ? 0.37167 0.34882 0.47596 0.09322  0.02055  -0.03665 251 GLN F OE1   
2434 N NE2   . GLN C 87 ? 0.29725 0.32521 0.40802 0.05378  -0.06962 -0.06982 251 GLN F NE2   
2443 N N     . PHE C 88 ? 0.23776 0.29494 0.22730 -0.01775 0.01244  -0.05994 252 PHE F N     
2444 C CA    . PHE C 88 ? 0.21329 0.30983 0.23320 -0.00513 -0.00896 -0.07090 252 PHE F CA    
2445 C C     . PHE C 88 ? 0.24641 0.33121 0.23568 0.00819  -0.00797 -0.08356 252 PHE F C     
2446 O O     . PHE C 88 ? 0.23308 0.33599 0.24609 0.01595  -0.01635 -0.07215 252 PHE F O     
2447 C CB    . PHE C 88 ? 0.17693 0.32828 0.23960 -0.00327 0.00350  -0.05215 252 PHE F CB    
2448 C CG    . PHE C 88 ? 0.16927 0.31643 0.24266 -0.00005 -0.00099 -0.03012 252 PHE F CG    
2449 C CD1   . PHE C 88 ? 0.19805 0.32452 0.22366 0.00843  0.00498  -0.00165 252 PHE F CD1   
2450 C CD2   . PHE C 88 ? 0.18766 0.32566 0.25062 -0.00994 0.01759  -0.03587 252 PHE F CD2   
2451 C CE1   . PHE C 88 ? 0.16783 0.32760 0.22587 0.00138  -0.00647 0.01265  252 PHE F CE1   
2452 C CE2   . PHE C 88 ? 0.18228 0.31203 0.24899 -0.01178 -0.00071 -0.01185 252 PHE F CE2   
2453 C CZ    . PHE C 88 ? 0.19574 0.32230 0.23300 -0.00062 0.01108  0.02776  252 PHE F CZ    
2463 N N     . SER C 89 ? 0.30021 0.35682 0.26725 0.02395  -0.00819 -0.09664 253 SER F N     
2464 C CA    . SER C 89 ? 0.31576 0.38729 0.31998 -0.00394 -0.00057 -0.11680 253 SER F CA    
2465 C C     . SER C 89 ? 0.28256 0.41944 0.33976 0.00783  -0.01278 -0.14281 253 SER F C     
2466 O O     . SER C 89 ? 0.28308 0.42248 0.31085 -0.00897 0.01876  -0.15425 253 SER F O     
2467 C CB    . SER C 89 ? 0.31158 0.38289 0.31156 -0.04607 -0.02768 -0.10876 253 SER F CB    
2468 O OG    . SER C 89 ? 0.34550 0.38345 0.32199 -0.03744 -0.00937 -0.09003 253 SER F OG    
2474 N N     . GLY C 90 ? 0.32630 0.44090 0.36301 -0.02024 0.01210  -0.17537 254 GLY F N     
2475 C CA    . GLY C 90 ? 0.34021 0.49000 0.34133 -0.00067 0.04923  -0.15906 254 GLY F CA    
2476 C C     . GLY C 90 ? 0.35221 0.51895 0.33879 -0.01323 0.06497  -0.15250 254 GLY F C     
2477 O O     . GLY C 90 ? 0.33781 0.53444 0.31668 -0.03470 0.04545  -0.13447 254 GLY F O     
2481 N N     . GLU C 91 ? 0.38275 0.53495 0.32740 -0.01729 0.03523  -0.14598 255 GLU F N     
2482 C CA    . GLU C 91 ? 0.42645 0.54336 0.37531 -0.03079 0.02594  -0.12505 255 GLU F CA    
2483 C C     . GLU C 91 ? 0.39181 0.55607 0.32517 -0.04894 0.00394  -0.11439 255 GLU F C     
2484 O O     . GLU C 91 ? 0.36443 0.57601 0.30667 -0.06054 -0.00988 -0.12072 255 GLU F O     
2485 C CB    . GLU C 91 ? 0.50869 0.54848 0.41712 -0.03076 -0.01537 -0.10542 255 GLU F CB    
2486 C CG    . GLU C 91 ? 0.59090 0.56438 0.49702 -0.02781 -0.00419 -0.04437 255 GLU F CG    
2487 C CD    . GLU C 91 ? 0.64373 0.58062 0.53254 -0.00893 -0.00182 -0.00103 255 GLU F CD    
2488 O OE1   . GLU C 91 ? 0.64569 0.58247 0.49151 -0.00269 -0.01375 -0.02992 255 GLU F OE1   
2489 O OE2   . GLU C 91 ? 0.66812 0.58049 0.55229 -0.00451 0.01525  0.02582  255 GLU F OE2   
2496 N N     . VAL C 92 ? 0.35606 0.54172 0.26443 -0.06307 0.00874  -0.11624 256 VAL F N     
2497 C CA    . VAL C 92 ? 0.32058 0.53441 0.25119 -0.05986 0.00170  -0.09353 256 VAL F CA    
2498 C C     . VAL C 92 ? 0.36182 0.52837 0.26574 -0.06152 0.02827  -0.09431 256 VAL F C     
2499 O O     . VAL C 92 ? 0.39171 0.53593 0.26636 -0.07846 -0.00715 -0.08131 256 VAL F O     
2500 C CB    . VAL C 92 ? 0.30328 0.54823 0.29060 -0.07891 0.01571  -0.10066 256 VAL F CB    
2501 C CG1   . VAL C 92 ? 0.31540 0.56159 0.27261 -0.07311 -0.01335 -0.09403 256 VAL F CG1   
2502 C CG2   . VAL C 92 ? 0.28374 0.55301 0.33090 -0.08642 -0.01525 -0.07194 256 VAL F CG2   
2512 N N     . LEU C 93 ? 0.34147 0.53216 0.28695 -0.04023 0.03715  -0.07382 257 LEU F N     
2513 C CA    . LEU C 93 ? 0.34321 0.56146 0.28374 -0.04419 0.01598  -0.08782 257 LEU F CA    
2514 C C     . LEU C 93 ? 0.36798 0.63090 0.27231 -0.04329 -0.00654 -0.06715 257 LEU F C     
2515 O O     . LEU C 93 ? 0.41254 0.63024 0.25116 -0.02063 0.00852  -0.02655 257 LEU F O     
2516 C CB    . LEU C 93 ? 0.31180 0.53566 0.27309 -0.07912 0.02850  -0.09448 257 LEU F CB    
2517 C CG    . LEU C 93 ? 0.36596 0.51990 0.26307 -0.08582 0.09122  -0.10876 257 LEU F CG    
2518 C CD1   . LEU C 93 ? 0.34741 0.51892 0.31623 -0.08536 0.06726  -0.09335 257 LEU F CD1   
2519 C CD2   . LEU C 93 ? 0.38332 0.51300 0.28269 -0.13717 0.11055  -0.12940 257 LEU F CD2   
2531 N N     . GLY C 94 ? 0.41244 0.68983 0.34182 -0.03701 0.10888  -0.12670 258 GLY F N     
2532 C CA    . GLY C 94 ? 0.53939 0.75795 0.47391 -0.03149 0.11692  -0.12332 258 GLY F CA    
2533 C C     . GLY C 94 ? 0.66372 0.83129 0.64404 -0.00859 0.11697  -0.10217 258 GLY F C     
2534 O O     . GLY C 94 ? 0.68323 0.84617 0.68959 -0.03078 0.09185  -0.10858 258 GLY F O     
2538 N N     . ARG C 95 ? 0.75289 0.88692 0.75465 0.05045  0.13773  -0.07269 259 ARG F N     
2539 C CA    . ARG C 95 ? 0.85792 0.93880 0.86603 0.10366  0.15737  -0.05149 259 ARG F CA    
2540 C C     . ARG C 95 ? 0.95591 0.97566 0.94491 0.13211  0.22202  -0.03031 259 ARG F C     
2541 O O     . ARG C 95 ? 1.01407 0.98771 1.00573 0.14232  0.26778  -0.01937 259 ARG F O     
2542 C CB    . ARG C 95 ? 0.85258 0.94259 0.87553 0.11347  0.13190  -0.03964 259 ARG F CB    
# 
