data_9NTJ
# 
_entry.id   9NTJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NTJ         pdb_00009ntj 10.2210/pdb9ntj/pdb 
WWPDB D_1000294157 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NTJ 
_pdbx_database_status.recvd_initial_deposition_date   2025-03-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              xcheng5@mdanderson.org 
_pdbx_contact_author.name_first         Xiaodong 
_pdbx_contact_author.name_last          Cheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6967-6362 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kaur, G.'     1 ? 
'Horton, J.R.' 2 ? 
'Cheng, X.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Biol.Chem. 
_citation.journal_id_ASTM           JBCHA3 
_citation.journal_id_CSD            0071 
_citation.journal_id_ISSN           1083-351X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                110357 
_citation.page_last                 110357 
_citation.title                     
'Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jbc.2025.110357 
_citation.pdbx_database_id_PubMed   40505866 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kaur, G.'        1 ? 
primary 'Horton, J.R.'    2 ? 
primary 'Tzertzinis, G.'  3 ? 
primary 'Zhou, J.'        4 ? 
primary 'Schildkraut, I.' 5 ? 
primary 'Cheng, X.'       6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Adenosine deaminase AGSA,Adenosine deaminase AGSA,AMP deaminase' 61383.203 2  3.5.4.4 ? 
'residues 1-120,residues 254-525' 
;residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA,residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA,residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA
;
2 branched    man 
;alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
748.682   1  ?       ? ?                                 ? 
3 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   7  ?       ? ?                                 ? 
4 non-polymer syn 1,2-ETHANEDIOL 62.068    6  ?       ? ?                                 ? 
5 non-polymer syn 'ZINC ION' 65.409    2  ?       ? ?                                 ? 
6 non-polymer syn "2'-DEOXYCOFORMYCIN" 268.269   2  ?       ? ?                                 ? 
7 water       nat water 18.015    79 ?       ? ?                                 ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Atrial gland-specific antigen,AGSA,Mollusk-derived growth factor,MDGF' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPA
NSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFR
SDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYP
DFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRF
TELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQ
LALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPA
NSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFR
SDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYP
DFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRF
TELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQ
LALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
4 1,2-ETHANEDIOL                           EDO 
5 'ZINC ION'                               ZN  
6 "2'-DEOXYCOFORMYCIN"                     DCF 
7 water                                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   SER n 
1 4   PHE n 
1 5   SER n 
1 6   THR n 
1 7   HIS n 
1 8   ASN n 
1 9   PHE n 
1 10  VAL n 
1 11  ALA n 
1 12  ILE n 
1 13  ALA n 
1 14  THR n 
1 15  PHE n 
1 16  VAL n 
1 17  CYS n 
1 18  TRP n 
1 19  PHE n 
1 20  CYS n 
1 21  CYS n 
1 22  LEU n 
1 23  ALA n 
1 24  THR n 
1 25  ALA n 
1 26  ALA n 
1 27  PRO n 
1 28  LEU n 
1 29  THR n 
1 30  SER n 
1 31  LYS n 
1 32  ALA n 
1 33  ALA n 
1 34  TYR n 
1 35  LEU n 
1 36  LEU n 
1 37  LYS n 
1 38  ARG n 
1 39  ASN n 
1 40  SER n 
1 41  LEU n 
1 42  ILE n 
1 43  GLU n 
1 44  GLU n 
1 45  ASP n 
1 46  ALA n 
1 47  SER n 
1 48  ARG n 
1 49  LYS n 
1 50  LEU n 
1 51  GLY n 
1 52  ALA n 
1 53  LYS n 
1 54  ILE n 
1 55  VAL n 
1 56  LEU n 
1 57  THR n 
1 58  ASN n 
1 59  GLU n 
1 60  GLU n 
1 61  LYS n 
1 62  VAL n 
1 63  LEU n 
1 64  ASP n 
1 65  ASP n 
1 66  PHE n 
1 67  ILE n 
1 68  LEU n 
1 69  ALA n 
1 70  GLU n 
1 71  LYS n 
1 72  ARG n 
1 73  LYS n 
1 74  LEU n 
1 75  ILE n 
1 76  ASP n 
1 77  ASP n 
1 78  SER n 
1 79  ARG n 
1 80  LEU n 
1 81  ASN n 
1 82  GLN n 
1 83  THR n 
1 84  GLU n 
1 85  TYR n 
1 86  MET n 
1 87  PRO n 
1 88  ALA n 
1 89  ALA n 
1 90  SER n 
1 91  PHE n 
1 92  TYR n 
1 93  ARG n 
1 94  SER n 
1 95  LYS n 
1 96  ASP n 
1 97  PHE n 
1 98  ILE n 
1 99  ASP n 
1 100 THR n 
1 101 THR n 
1 102 PHE n 
1 103 ALA n 
1 104 TYR n 
1 105 LYS n 
1 106 ILE n 
1 107 ILE n 
1 108 GLN n 
1 109 ASP n 
1 110 MET n 
1 111 PRO n 
1 112 LYS n 
1 113 GLY n 
1 114 GLY n 
1 115 ALA n 
1 116 LEU n 
1 117 HIS n 
1 118 LEU n 
1 119 HIS n 
1 120 ASP n 
1 121 THR n 
1 122 ALA n 
1 123 SER n 
1 124 ALA n 
1 125 ARG n 
1 126 ILE n 
1 127 ASP n 
1 128 TRP n 
1 129 ILE n 
1 130 VAL n 
1 131 SER n 
1 132 ASN n 
1 133 ALA n 
1 134 THR n 
1 135 TYR n 
1 136 ARG n 
1 137 ASP n 
1 138 HIS n 
1 139 VAL n 
1 140 TYR n 
1 141 MET n 
1 142 CYS n 
1 143 MET n 
1 144 ASP n 
1 145 GLN n 
1 146 ASP n 
1 147 ASN n 
1 148 PHE n 
1 149 VAL n 
1 150 ARG n 
1 151 LEU n 
1 152 THR n 
1 153 VAL n 
1 154 SER n 
1 155 GLY n 
1 156 THR n 
1 157 GLY n 
1 158 PRO n 
1 159 PRO n 
1 160 ALA n 
1 161 ASN n 
1 162 SER n 
1 163 GLY n 
1 164 CYS n 
1 165 GLU n 
1 166 TRP n 
1 167 LYS n 
1 168 LEU n 
1 169 VAL n 
1 170 GLU n 
1 171 THR n 
1 172 GLU n 
1 173 ARG n 
1 174 ALA n 
1 175 ASN n 
1 176 SER n 
1 177 GLY n 
1 178 ASP n 
1 179 ILE n 
1 180 ALA n 
1 181 ALA n 
1 182 PHE n 
1 183 ASP n 
1 184 HIS n 
1 185 TRP n 
1 186 LEU n 
1 187 LYS n 
1 188 SER n 
1 189 ASN n 
1 190 ILE n 
1 191 SER n 
1 192 LEU n 
1 193 LEU n 
1 194 THR n 
1 195 THR n 
1 196 ASP n 
1 197 PRO n 
1 198 LEU n 
1 199 VAL n 
1 200 THR n 
1 201 TYR n 
1 202 PRO n 
1 203 SER n 
1 204 LEU n 
1 205 ASP n 
1 206 LYS n 
1 207 VAL n 
1 208 TRP n 
1 209 GLY n 
1 210 ARG n 
1 211 PHE n 
1 212 ASP n 
1 213 LYS n 
1 214 HIS n 
1 215 PHE n 
1 216 SER n 
1 217 GLN n 
1 218 LEU n 
1 219 ARG n 
1 220 GLY n 
1 221 ILE n 
1 222 ILE n 
1 223 TYR n 
1 224 HIS n 
1 225 THR n 
1 226 PRO n 
1 227 ILE n 
1 228 ARG n 
1 229 ARG n 
1 230 ASP n 
1 231 TYR n 
1 232 TYR n 
1 233 ARG n 
1 234 GLN n 
1 235 ILE n 
1 236 LEU n 
1 237 GLU n 
1 238 GLU n 
1 239 PHE n 
1 240 ARG n 
1 241 SER n 
1 242 ASP n 
1 243 ASN n 
1 244 VAL n 
1 245 GLN n 
1 246 TYR n 
1 247 VAL n 
1 248 GLU n 
1 249 VAL n 
1 250 ARG n 
1 251 SER n 
1 252 SER n 
1 253 LEU n 
1 254 SER n 
1 255 GLY n 
1 256 PHE n 
1 257 PHE n 
1 258 GLU n 
1 259 LEU n 
1 260 ASP n 
1 261 GLY n 
1 262 THR n 
1 263 VAL n 
1 264 HIS n 
1 265 ASP n 
1 266 ALA n 
1 267 GLU n 
1 268 PHE n 
1 269 GLY n 
1 270 LEU n 
1 271 ASN n 
1 272 LEU n 
1 273 TYR n 
1 274 LYS n 
1 275 SER n 
1 276 VAL n 
1 277 THR n 
1 278 GLU n 
1 279 GLU n 
1 280 PHE n 
1 281 GLN n 
1 282 ARG n 
1 283 GLU n 
1 284 TYR n 
1 285 PRO n 
1 286 ASP n 
1 287 PHE n 
1 288 ILE n 
1 289 GLY n 
1 290 ALA n 
1 291 LYS n 
1 292 ILE n 
1 293 ILE n 
1 294 LEU n 
1 295 SER n 
1 296 GLY n 
1 297 LEU n 
1 298 ARG n 
1 299 PHE n 
1 300 LYS n 
1 301 SER n 
1 302 GLN n 
1 303 GLU n 
1 304 GLU n 
1 305 ILE n 
1 306 LEU n 
1 307 ASN n 
1 308 GLU n 
1 309 VAL n 
1 310 LYS n 
1 311 ILE n 
1 312 ALA n 
1 313 MET n 
1 314 ASP n 
1 315 LEU n 
1 316 HIS n 
1 317 LYS n 
1 318 LYS n 
1 319 TYR n 
1 320 PRO n 
1 321 ASP n 
1 322 PHE n 
1 323 PHE n 
1 324 LEU n 
1 325 GLY n 
1 326 TYR n 
1 327 ASP n 
1 328 LEU n 
1 329 VAL n 
1 330 GLY n 
1 331 GLN n 
1 332 GLU n 
1 333 ASP n 
1 334 PRO n 
1 335 ASN n 
1 336 PHE n 
1 337 SER n 
1 338 LEU n 
1 339 LEU n 
1 340 HIS n 
1 341 TYR n 
1 342 LEU n 
1 343 ASP n 
1 344 ALA n 
1 345 LEU n 
1 346 LEU n 
1 347 TYR n 
1 348 PRO n 
1 349 SER n 
1 350 ILE n 
1 351 GLN n 
1 352 ASN n 
1 353 PRO n 
1 354 PRO n 
1 355 TYR n 
1 356 ARG n 
1 357 LEU n 
1 358 PRO n 
1 359 TYR n 
1 360 PHE n 
1 361 PHE n 
1 362 HIS n 
1 363 ALA n 
1 364 ALA n 
1 365 GLU n 
1 366 THR n 
1 367 ASN n 
1 368 TRP n 
1 369 GLN n 
1 370 GLU n 
1 371 THR n 
1 372 GLU n 
1 373 VAL n 
1 374 ASP n 
1 375 TYR n 
1 376 ASN n 
1 377 LEU n 
1 378 ALA n 
1 379 ASP n 
1 380 ALA n 
1 381 LEU n 
1 382 LEU n 
1 383 LEU n 
1 384 ASN n 
1 385 THR n 
1 386 THR n 
1 387 ARG n 
1 388 VAL n 
1 389 GLY n 
1 390 HIS n 
1 391 GLY n 
1 392 PHE n 
1 393 ALA n 
1 394 LEU n 
1 395 ILE n 
1 396 LYS n 
1 397 HIS n 
1 398 PRO n 
1 399 ARG n 
1 400 PHE n 
1 401 THR n 
1 402 GLU n 
1 403 LEU n 
1 404 ALA n 
1 405 LYS n 
1 406 GLU n 
1 407 ASN n 
1 408 GLY n 
1 409 VAL n 
1 410 ALA n 
1 411 VAL n 
1 412 GLU n 
1 413 VAL n 
1 414 ASN n 
1 415 PRO n 
1 416 ILE n 
1 417 SER n 
1 418 ASN n 
1 419 GLN n 
1 420 ILE n 
1 421 LEU n 
1 422 GLY n 
1 423 LEU n 
1 424 VAL n 
1 425 ARG n 
1 426 ASP n 
1 427 VAL n 
1 428 ARG n 
1 429 ASN n 
1 430 HIS n 
1 431 ALA n 
1 432 LEU n 
1 433 VAL n 
1 434 PRO n 
1 435 LEU n 
1 436 ILE n 
1 437 ALA n 
1 438 ASP n 
1 439 ASP n 
1 440 TYR n 
1 441 PRO n 
1 442 ILE n 
1 443 VAL n 
1 444 ILE n 
1 445 SER n 
1 446 SER n 
1 447 ASP n 
1 448 ASP n 
1 449 PRO n 
1 450 GLY n 
1 451 ALA n 
1 452 TRP n 
1 453 GLU n 
1 454 ALA n 
1 455 SER n 
1 456 PRO n 
1 457 LEU n 
1 458 SER n 
1 459 HIS n 
1 460 ASP n 
1 461 PHE n 
1 462 TYR n 
1 463 VAL n 
1 464 ALA n 
1 465 LEU n 
1 466 MET n 
1 467 ASP n 
1 468 LEU n 
1 469 CYS n 
1 470 GLY n 
1 471 ARG n 
1 472 ASP n 
1 473 THR n 
1 474 ALA n 
1 475 LEU n 
1 476 THR n 
1 477 PHE n 
1 478 LEU n 
1 479 LYS n 
1 480 GLN n 
1 481 LEU n 
1 482 ALA n 
1 483 LEU n 
1 484 ASN n 
1 485 SER n 
1 486 ILE n 
1 487 ARG n 
1 488 TYR n 
1 489 SER n 
1 490 ALA n 
1 491 MET n 
1 492 SER n 
1 493 ASP n 
1 494 THR n 
1 495 GLU n 
1 496 LYS n 
1 497 VAL n 
1 498 ALA n 
1 499 ALA n 
1 500 LYS n 
1 501 ALA n 
1 502 LYS n 
1 503 TRP n 
1 504 THR n 
1 505 THR n 
1 506 GLN n 
1 507 TRP n 
1 508 ASP n 
1 509 LYS n 
1 510 PHE n 
1 511 VAL n 
1 512 LYS n 
1 513 THR n 
1 514 SER n 
1 515 VAL n 
1 516 GLU n 
1 517 GLY n 
1 518 LEU n 
1 519 LYS n 
1 520 PRO n 
1 521 HIS n 
1 522 ILE n 
1 523 ASN n 
1 524 ASP n 
1 525 ARG n 
1 526 SER n 
1 527 HIS n 
1 528 HIS n 
1 529 HIS n 
1 530 HIS n 
1 531 HIS n 
1 532 HIS n 
1 533 HIS n 
1 534 HIS n 
1 535 HIS n 
1 536 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   120 'California sea hare' ? ? ? ? ? ? ? ? 'Aplysia californica' 6500 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 121 254 ?                     ? ? ? ? ? ? ? ? 'Helix pomatia'       6536 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 255 536 'California sea hare' ? ? ? ? ? ? ? ? 'Aplysia californica' 6500 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DManpa1-6DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH                                                        
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3/a4-b1_b4-c1_c6-d1' WURCS PDB2Glycan 1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(6+1)][a-D-Manp]{}}}}'               LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 2 4 MAN C1 O1 3 BMA O6 HO6 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
DCF non-polymer                   . "2'-DEOXYCOFORMYCIN"                     ? 'C11 H16 N4 O4'  268.269 
EDO non-polymer                   . 1,2-ETHANEDIOL                           'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
ZN  non-polymer                   . 'ZINC ION'                               ? 'Zn 2'           65.409  
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   PHE 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   ?   ?   ?   A . n 
A 1 7   HIS 7   7   ?   ?   ?   A . n 
A 1 8   ASN 8   8   ?   ?   ?   A . n 
A 1 9   PHE 9   9   ?   ?   ?   A . n 
A 1 10  VAL 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  ILE 12  12  ?   ?   ?   A . n 
A 1 13  ALA 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  PHE 15  15  ?   ?   ?   A . n 
A 1 16  VAL 16  16  ?   ?   ?   A . n 
A 1 17  CYS 17  17  ?   ?   ?   A . n 
A 1 18  TRP 18  18  ?   ?   ?   A . n 
A 1 19  PHE 19  19  ?   ?   ?   A . n 
A 1 20  CYS 20  20  ?   ?   ?   A . n 
A 1 21  CYS 21  21  ?   ?   ?   A . n 
A 1 22  LEU 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  THR 24  24  ?   ?   ?   A . n 
A 1 25  ALA 25  25  ?   ?   ?   A . n 
A 1 26  ALA 26  26  ?   ?   ?   A . n 
A 1 27  PRO 27  27  ?   ?   ?   A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  ALA 32  32  32  ALA ALA A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ASP 45  45  45  ASP ASP A . n 
A 1 46  ALA 46  46  46  ALA ALA A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  LEU 56  56  56  LEU LEU A . n 
A 1 57  THR 57  57  57  THR THR A . n 
A 1 58  ASN 58  58  58  ASN ASN A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLU 60  60  60  GLU GLU A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  ASP 64  64  64  ASP ASP A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  LYS 71  71  71  LYS LYS A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  ILE 75  75  75  ILE ILE A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  ASP 77  77  77  ASP ASP A . n 
A 1 78  SER 78  78  78  SER SER A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  ASN 81  81  81  ASN ASN A . n 
A 1 82  GLN 82  82  82  GLN GLN A . n 
A 1 83  THR 83  83  83  THR THR A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  TYR 85  85  85  TYR TYR A . n 
A 1 86  MET 86  86  86  MET MET A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  PHE 97  97  97  PHE PHE A . n 
A 1 98  ILE 98  98  98  ILE ILE A . n 
A 1 99  ASP 99  99  99  ASP ASP A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 PHE 102 102 102 PHE PHE A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 LYS 105 105 105 LYS LYS A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 GLN 108 108 108 GLN GLN A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 PRO 111 111 111 PRO PRO A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 GLY 113 113 113 GLY GLY A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 HIS 117 117 117 HIS HIS A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 HIS 119 119 119 HIS HIS A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 THR 121 121 121 THR THR A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 ASP 127 127 127 ASP ASP A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 ASN 132 132 132 ASN ASN A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 TYR 135 135 135 TYR TYR A . n 
A 1 136 ARG 136 136 136 ARG ARG A . n 
A 1 137 ASP 137 137 137 ASP ASP A . n 
A 1 138 HIS 138 138 138 HIS HIS A . n 
A 1 139 VAL 139 139 139 VAL VAL A . n 
A 1 140 TYR 140 140 140 TYR TYR A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 CYS 142 142 142 CYS CYS A . n 
A 1 143 MET 143 143 143 MET MET A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 GLN 145 145 145 GLN GLN A . n 
A 1 146 ASP 146 146 146 ASP ASP A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 THR 156 156 156 THR THR A . n 
A 1 157 GLY 157 157 157 GLY GLY A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ASN 161 161 161 ASN ASN A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 CYS 164 164 164 CYS CYS A . n 
A 1 165 GLU 165 165 165 GLU GLU A . n 
A 1 166 TRP 166 166 166 TRP TRP A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 VAL 169 169 169 VAL VAL A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 GLU 172 172 172 GLU GLU A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 ASP 178 178 178 ASP ASP A . n 
A 1 179 ILE 179 179 179 ILE ILE A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 PHE 182 182 182 PHE PHE A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 HIS 184 184 184 HIS HIS A . n 
A 1 185 TRP 185 185 185 TRP TRP A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 LYS 187 187 187 LYS LYS A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 THR 200 200 200 THR THR A . n 
A 1 201 TYR 201 201 201 TYR TYR A . n 
A 1 202 PRO 202 202 202 PRO PRO A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 ASP 205 205 205 ASP ASP A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 VAL 207 207 207 VAL VAL A . n 
A 1 208 TRP 208 208 208 TRP TRP A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 PHE 211 211 211 PHE PHE A . n 
A 1 212 ASP 212 212 212 ASP ASP A . n 
A 1 213 LYS 213 213 213 LYS LYS A . n 
A 1 214 HIS 214 214 214 HIS HIS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 ARG 219 219 219 ARG ARG A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 TYR 223 223 223 TYR TYR A . n 
A 1 224 HIS 224 224 224 HIS HIS A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 PRO 226 226 226 PRO PRO A . n 
A 1 227 ILE 227 227 227 ILE ILE A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 ASP 230 230 230 ASP ASP A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 TYR 232 232 232 TYR TYR A . n 
A 1 233 ARG 233 233 233 ARG ARG A . n 
A 1 234 GLN 234 234 234 GLN GLN A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 GLU 237 237 237 GLU GLU A . n 
A 1 238 GLU 238 238 238 GLU GLU A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 ARG 240 240 240 ARG ARG A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 ASN 243 243 243 ASN ASN A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 GLN 245 245 245 GLN GLN A . n 
A 1 246 TYR 246 246 246 TYR TYR A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 GLY 255 255 255 GLY GLY A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 ASP 260 260 260 ASP ASP A . n 
A 1 261 GLY 261 261 261 GLY GLY A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 VAL 263 263 263 VAL VAL A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 ASP 265 265 265 ASP ASP A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 GLU 267 267 267 GLU GLU A . n 
A 1 268 PHE 268 268 268 PHE PHE A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 ASN 271 271 271 ASN ASN A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 TYR 273 273 273 TYR TYR A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 THR 277 277 277 THR THR A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 GLU 279 279 279 GLU GLU A . n 
A 1 280 PHE 280 280 280 PHE PHE A . n 
A 1 281 GLN 281 281 281 GLN GLN A . n 
A 1 282 ARG 282 282 282 ARG ARG A . n 
A 1 283 GLU 283 283 283 GLU GLU A . n 
A 1 284 TYR 284 284 284 TYR TYR A . n 
A 1 285 PRO 285 285 285 PRO PRO A . n 
A 1 286 ASP 286 286 286 ASP ASP A . n 
A 1 287 PHE 287 287 287 PHE PHE A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 GLY 289 289 289 GLY GLY A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 ILE 292 292 292 ILE ILE A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 GLN 302 302 302 GLN GLN A . n 
A 1 303 GLU 303 303 303 GLU GLU A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 ILE 305 305 305 ILE ILE A . n 
A 1 306 LEU 306 306 306 LEU LEU A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 VAL 309 309 309 VAL VAL A . n 
A 1 310 LYS 310 310 310 LYS LYS A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 ALA 312 312 312 ALA ALA A . n 
A 1 313 MET 313 313 313 MET MET A . n 
A 1 314 ASP 314 314 314 ASP ASP A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 HIS 316 316 316 HIS HIS A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 TYR 319 319 319 TYR TYR A . n 
A 1 320 PRO 320 320 320 PRO PRO A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 PHE 323 323 323 PHE PHE A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 GLY 325 325 325 GLY GLY A . n 
A 1 326 TYR 326 326 326 TYR TYR A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 VAL 329 329 329 VAL VAL A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 GLN 331 331 331 GLN GLN A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 ASP 333 333 333 ASP ASP A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 ASN 335 335 335 ASN ASN A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 SER 337 337 337 SER SER A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 HIS 340 340 340 HIS HIS A . n 
A 1 341 TYR 341 341 341 TYR TYR A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 TYR 347 347 347 TYR TYR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 SER 349 349 349 SER SER A . n 
A 1 350 ILE 350 350 350 ILE ILE A . n 
A 1 351 GLN 351 351 351 GLN GLN A . n 
A 1 352 ASN 352 352 352 ASN ASN A . n 
A 1 353 PRO 353 353 353 PRO PRO A . n 
A 1 354 PRO 354 354 354 PRO PRO A . n 
A 1 355 TYR 355 355 355 TYR TYR A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 TYR 359 359 359 TYR TYR A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 PHE 361 361 361 PHE PHE A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 ALA 364 364 364 ALA ALA A . n 
A 1 365 GLU 365 365 365 GLU GLU A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 ASN 367 367 367 ASN ASN A . n 
A 1 368 TRP 368 368 368 TRP TRP A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 THR 371 371 371 THR THR A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 TYR 375 375 375 TYR TYR A . n 
A 1 376 ASN 376 376 376 ASN ASN A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 ALA 378 378 378 ALA ALA A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 THR 385 385 385 THR THR A . n 
A 1 386 THR 386 386 386 THR THR A . n 
A 1 387 ARG 387 387 387 ARG ARG A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 HIS 390 390 390 HIS HIS A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 ALA 393 393 393 ALA ALA A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 ILE 395 395 395 ILE ILE A . n 
A 1 396 LYS 396 396 396 LYS LYS A . n 
A 1 397 HIS 397 397 397 HIS HIS A . n 
A 1 398 PRO 398 398 398 PRO PRO A . n 
A 1 399 ARG 399 399 399 ARG ARG A . n 
A 1 400 PHE 400 400 400 PHE PHE A . n 
A 1 401 THR 401 401 401 THR THR A . n 
A 1 402 GLU 402 402 402 GLU GLU A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 ALA 404 404 404 ALA ALA A . n 
A 1 405 LYS 405 405 405 LYS LYS A . n 
A 1 406 GLU 406 406 406 GLU GLU A . n 
A 1 407 ASN 407 407 407 ASN ASN A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 ALA 410 410 410 ALA ALA A . n 
A 1 411 VAL 411 411 411 VAL VAL A . n 
A 1 412 GLU 412 412 412 GLU GLU A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 ASN 414 414 414 ASN ASN A . n 
A 1 415 PRO 415 415 415 PRO PRO A . n 
A 1 416 ILE 416 416 416 ILE ILE A . n 
A 1 417 SER 417 417 417 SER SER A . n 
A 1 418 ASN 418 418 418 ASN ASN A . n 
A 1 419 GLN 419 419 419 GLN GLN A . n 
A 1 420 ILE 420 420 420 ILE ILE A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 GLY 422 422 422 GLY GLY A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 VAL 424 424 424 VAL VAL A . n 
A 1 425 ARG 425 425 425 ARG ARG A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 VAL 427 427 427 VAL VAL A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 ASN 429 429 429 ASN ASN A . n 
A 1 430 HIS 430 430 430 HIS HIS A . n 
A 1 431 ALA 431 431 431 ALA ALA A . n 
A 1 432 LEU 432 432 432 LEU LEU A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 PRO 434 434 434 PRO PRO A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 ILE 436 436 436 ILE ILE A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 ASP 438 438 438 ASP ASP A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 TYR 440 440 440 TYR TYR A . n 
A 1 441 PRO 441 441 441 PRO PRO A . n 
A 1 442 ILE 442 442 442 ILE ILE A . n 
A 1 443 VAL 443 443 443 VAL VAL A . n 
A 1 444 ILE 444 444 444 ILE ILE A . n 
A 1 445 SER 445 445 445 SER SER A . n 
A 1 446 SER 446 446 446 SER SER A . n 
A 1 447 ASP 447 447 447 ASP ASP A . n 
A 1 448 ASP 448 448 448 ASP ASP A . n 
A 1 449 PRO 449 449 449 PRO PRO A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 ALA 451 451 451 ALA ALA A . n 
A 1 452 TRP 452 452 452 TRP TRP A . n 
A 1 453 GLU 453 453 453 GLU GLU A . n 
A 1 454 ALA 454 454 454 ALA ALA A . n 
A 1 455 SER 455 455 455 SER SER A . n 
A 1 456 PRO 456 456 456 PRO PRO A . n 
A 1 457 LEU 457 457 457 LEU LEU A . n 
A 1 458 SER 458 458 458 SER SER A . n 
A 1 459 HIS 459 459 459 HIS HIS A . n 
A 1 460 ASP 460 460 460 ASP ASP A . n 
A 1 461 PHE 461 461 461 PHE PHE A . n 
A 1 462 TYR 462 462 462 TYR TYR A . n 
A 1 463 VAL 463 463 463 VAL VAL A . n 
A 1 464 ALA 464 464 464 ALA ALA A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 MET 466 466 466 MET MET A . n 
A 1 467 ASP 467 467 467 ASP ASP A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 CYS 469 469 469 CYS CYS A . n 
A 1 470 GLY 470 470 470 GLY GLY A . n 
A 1 471 ARG 471 471 471 ARG ARG A . n 
A 1 472 ASP 472 472 472 ASP ASP A . n 
A 1 473 THR 473 473 473 THR THR A . n 
A 1 474 ALA 474 474 474 ALA ALA A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 PHE 477 477 477 PHE PHE A . n 
A 1 478 LEU 478 478 478 LEU LEU A . n 
A 1 479 LYS 479 479 479 LYS LYS A . n 
A 1 480 GLN 480 480 480 GLN GLN A . n 
A 1 481 LEU 481 481 481 LEU LEU A . n 
A 1 482 ALA 482 482 482 ALA ALA A . n 
A 1 483 LEU 483 483 483 LEU LEU A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 SER 485 485 485 SER SER A . n 
A 1 486 ILE 486 486 486 ILE ILE A . n 
A 1 487 ARG 487 487 487 ARG ARG A . n 
A 1 488 TYR 488 488 488 TYR TYR A . n 
A 1 489 SER 489 489 489 SER SER A . n 
A 1 490 ALA 490 490 490 ALA ALA A . n 
A 1 491 MET 491 491 491 MET MET A . n 
A 1 492 SER 492 492 492 SER SER A . n 
A 1 493 ASP 493 493 493 ASP ASP A . n 
A 1 494 THR 494 494 494 THR THR A . n 
A 1 495 GLU 495 495 495 GLU GLU A . n 
A 1 496 LYS 496 496 496 LYS LYS A . n 
A 1 497 VAL 497 497 497 VAL VAL A . n 
A 1 498 ALA 498 498 498 ALA ALA A . n 
A 1 499 ALA 499 499 499 ALA ALA A . n 
A 1 500 LYS 500 500 500 LYS LYS A . n 
A 1 501 ALA 501 501 501 ALA ALA A . n 
A 1 502 LYS 502 502 502 LYS LYS A . n 
A 1 503 TRP 503 503 503 TRP TRP A . n 
A 1 504 THR 504 504 504 THR THR A . n 
A 1 505 THR 505 505 505 THR THR A . n 
A 1 506 GLN 506 506 506 GLN GLN A . n 
A 1 507 TRP 507 507 507 TRP TRP A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 LYS 509 509 509 LYS LYS A . n 
A 1 510 PHE 510 510 510 PHE PHE A . n 
A 1 511 VAL 511 511 511 VAL VAL A . n 
A 1 512 LYS 512 512 512 LYS LYS A . n 
A 1 513 THR 513 513 513 THR THR A . n 
A 1 514 SER 514 514 514 SER SER A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 GLU 516 516 516 GLU GLU A . n 
A 1 517 GLY 517 517 517 GLY GLY A . n 
A 1 518 LEU 518 518 518 LEU LEU A . n 
A 1 519 LYS 519 519 519 LYS LYS A . n 
A 1 520 PRO 520 520 520 PRO PRO A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 ILE 522 522 ?   ?   ?   A . n 
A 1 523 ASN 523 523 ?   ?   ?   A . n 
A 1 524 ASP 524 524 ?   ?   ?   A . n 
A 1 525 ARG 525 525 ?   ?   ?   A . n 
A 1 526 SER 526 526 ?   ?   ?   A . n 
A 1 527 HIS 527 527 ?   ?   ?   A . n 
A 1 528 HIS 528 528 ?   ?   ?   A . n 
A 1 529 HIS 529 529 ?   ?   ?   A . n 
A 1 530 HIS 530 530 ?   ?   ?   A . n 
A 1 531 HIS 531 531 ?   ?   ?   A . n 
A 1 532 HIS 532 532 ?   ?   ?   A . n 
A 1 533 HIS 533 533 ?   ?   ?   A . n 
A 1 534 HIS 534 534 ?   ?   ?   A . n 
A 1 535 HIS 535 535 ?   ?   ?   A . n 
A 1 536 HIS 536 536 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   SER 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   PHE 4   4   ?   ?   ?   B . n 
B 1 5   SER 5   5   ?   ?   ?   B . n 
B 1 6   THR 6   6   ?   ?   ?   B . n 
B 1 7   HIS 7   7   ?   ?   ?   B . n 
B 1 8   ASN 8   8   ?   ?   ?   B . n 
B 1 9   PHE 9   9   ?   ?   ?   B . n 
B 1 10  VAL 10  10  ?   ?   ?   B . n 
B 1 11  ALA 11  11  ?   ?   ?   B . n 
B 1 12  ILE 12  12  ?   ?   ?   B . n 
B 1 13  ALA 13  13  ?   ?   ?   B . n 
B 1 14  THR 14  14  ?   ?   ?   B . n 
B 1 15  PHE 15  15  ?   ?   ?   B . n 
B 1 16  VAL 16  16  ?   ?   ?   B . n 
B 1 17  CYS 17  17  ?   ?   ?   B . n 
B 1 18  TRP 18  18  ?   ?   ?   B . n 
B 1 19  PHE 19  19  ?   ?   ?   B . n 
B 1 20  CYS 20  20  ?   ?   ?   B . n 
B 1 21  CYS 21  21  ?   ?   ?   B . n 
B 1 22  LEU 22  22  ?   ?   ?   B . n 
B 1 23  ALA 23  23  ?   ?   ?   B . n 
B 1 24  THR 24  24  ?   ?   ?   B . n 
B 1 25  ALA 25  25  ?   ?   ?   B . n 
B 1 26  ALA 26  26  ?   ?   ?   B . n 
B 1 27  PRO 27  27  ?   ?   ?   B . n 
B 1 28  LEU 28  28  28  LEU LEU B . n 
B 1 29  THR 29  29  29  THR THR B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  LYS 31  31  31  LYS LYS B . n 
B 1 32  ALA 32  32  32  ALA ALA B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  TYR 34  34  34  TYR TYR B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  LYS 37  37  37  LYS LYS B . n 
B 1 38  ARG 38  38  38  ARG ARG B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  ILE 42  42  42  ILE ILE B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  GLU 44  44  44  GLU GLU B . n 
B 1 45  ASP 45  45  45  ASP ASP B . n 
B 1 46  ALA 46  46  46  ALA ALA B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  LYS 49  49  49  LYS LYS B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  ALA 52  52  52  ALA ALA B . n 
B 1 53  LYS 53  53  53  LYS LYS B . n 
B 1 54  ILE 54  54  54  ILE ILE B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  LEU 56  56  56  LEU LEU B . n 
B 1 57  THR 57  57  57  THR THR B . n 
B 1 58  ASN 58  58  58  ASN ASN B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLU 60  60  60  GLU GLU B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  VAL 62  62  62  VAL VAL B . n 
B 1 63  LEU 63  63  63  LEU LEU B . n 
B 1 64  ASP 64  64  64  ASP ASP B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  ILE 67  67  67  ILE ILE B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  LYS 71  71  71  LYS LYS B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  LYS 73  73  73  LYS LYS B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  ILE 75  75  75  ILE ILE B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  ASP 77  77  77  ASP ASP B . n 
B 1 78  SER 78  78  78  SER SER B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  ASN 81  81  81  ASN ASN B . n 
B 1 82  GLN 82  82  82  GLN GLN B . n 
B 1 83  THR 83  83  83  THR THR B . n 
B 1 84  GLU 84  84  84  GLU GLU B . n 
B 1 85  TYR 85  85  85  TYR TYR B . n 
B 1 86  MET 86  86  86  MET MET B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  ALA 89  89  89  ALA ALA B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  TYR 92  92  92  TYR TYR B . n 
B 1 93  ARG 93  93  93  ARG ARG B . n 
B 1 94  SER 94  94  94  SER SER B . n 
B 1 95  LYS 95  95  95  LYS LYS B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  PHE 97  97  97  PHE PHE B . n 
B 1 98  ILE 98  98  98  ILE ILE B . n 
B 1 99  ASP 99  99  99  ASP ASP B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 PHE 102 102 102 PHE PHE B . n 
B 1 103 ALA 103 103 103 ALA ALA B . n 
B 1 104 TYR 104 104 104 TYR TYR B . n 
B 1 105 LYS 105 105 105 LYS LYS B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 GLN 108 108 108 GLN GLN B . n 
B 1 109 ASP 109 109 109 ASP ASP B . n 
B 1 110 MET 110 110 110 MET MET B . n 
B 1 111 PRO 111 111 111 PRO PRO B . n 
B 1 112 LYS 112 112 112 LYS LYS B . n 
B 1 113 GLY 113 113 113 GLY GLY B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 ALA 115 115 115 ALA ALA B . n 
B 1 116 LEU 116 116 116 LEU LEU B . n 
B 1 117 HIS 117 117 117 HIS HIS B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 HIS 119 119 119 HIS HIS B . n 
B 1 120 ASP 120 120 120 ASP ASP B . n 
B 1 121 THR 121 121 121 THR THR B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 ARG 125 125 125 ARG ARG B . n 
B 1 126 ILE 126 126 126 ILE ILE B . n 
B 1 127 ASP 127 127 127 ASP ASP B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 ILE 129 129 129 ILE ILE B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 ASN 132 132 132 ASN ASN B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 THR 134 134 134 THR THR B . n 
B 1 135 TYR 135 135 135 TYR TYR B . n 
B 1 136 ARG 136 136 136 ARG ARG B . n 
B 1 137 ASP 137 137 137 ASP ASP B . n 
B 1 138 HIS 138 138 138 HIS HIS B . n 
B 1 139 VAL 139 139 139 VAL VAL B . n 
B 1 140 TYR 140 140 140 TYR TYR B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 CYS 142 142 142 CYS CYS B . n 
B 1 143 MET 143 143 143 MET MET B . n 
B 1 144 ASP 144 144 144 ASP ASP B . n 
B 1 145 GLN 145 145 145 GLN GLN B . n 
B 1 146 ASP 146 146 146 ASP ASP B . n 
B 1 147 ASN 147 147 147 ASN ASN B . n 
B 1 148 PHE 148 148 148 PHE PHE B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 THR 152 152 152 THR THR B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 SER 154 154 154 SER SER B . n 
B 1 155 GLY 155 155 155 GLY GLY B . n 
B 1 156 THR 156 156 156 THR THR B . n 
B 1 157 GLY 157 157 157 GLY GLY B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 PRO 159 159 159 PRO PRO B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 ASN 161 161 161 ASN ASN B . n 
B 1 162 SER 162 162 162 SER SER B . n 
B 1 163 GLY 163 163 163 GLY GLY B . n 
B 1 164 CYS 164 164 164 CYS CYS B . n 
B 1 165 GLU 165 165 165 GLU GLU B . n 
B 1 166 TRP 166 166 166 TRP TRP B . n 
B 1 167 LYS 167 167 167 LYS LYS B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 VAL 169 169 169 VAL VAL B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 THR 171 171 171 THR THR B . n 
B 1 172 GLU 172 172 172 GLU GLU B . n 
B 1 173 ARG 173 173 173 ARG ARG B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 ASN 175 175 175 ASN ASN B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 ASP 178 178 178 ASP ASP B . n 
B 1 179 ILE 179 179 179 ILE ILE B . n 
B 1 180 ALA 180 180 180 ALA ALA B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 PHE 182 182 182 PHE PHE B . n 
B 1 183 ASP 183 183 183 ASP ASP B . n 
B 1 184 HIS 184 184 184 HIS HIS B . n 
B 1 185 TRP 185 185 185 TRP TRP B . n 
B 1 186 LEU 186 186 186 LEU LEU B . n 
B 1 187 LYS 187 187 187 LYS LYS B . n 
B 1 188 SER 188 188 188 SER SER B . n 
B 1 189 ASN 189 189 189 ASN ASN B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 THR 194 194 194 THR THR B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 ASP 196 196 196 ASP ASP B . n 
B 1 197 PRO 197 197 197 PRO PRO B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 VAL 199 199 199 VAL VAL B . n 
B 1 200 THR 200 200 200 THR THR B . n 
B 1 201 TYR 201 201 201 TYR TYR B . n 
B 1 202 PRO 202 202 202 PRO PRO B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 ASP 205 205 205 ASP ASP B . n 
B 1 206 LYS 206 206 206 LYS LYS B . n 
B 1 207 VAL 207 207 207 VAL VAL B . n 
B 1 208 TRP 208 208 208 TRP TRP B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 ARG 210 210 210 ARG ARG B . n 
B 1 211 PHE 211 211 211 PHE PHE B . n 
B 1 212 ASP 212 212 212 ASP ASP B . n 
B 1 213 LYS 213 213 213 LYS LYS B . n 
B 1 214 HIS 214 214 214 HIS HIS B . n 
B 1 215 PHE 215 215 215 PHE PHE B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 LEU 218 218 218 LEU LEU B . n 
B 1 219 ARG 219 219 219 ARG ARG B . n 
B 1 220 GLY 220 220 220 GLY GLY B . n 
B 1 221 ILE 221 221 221 ILE ILE B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 TYR 223 223 223 TYR TYR B . n 
B 1 224 HIS 224 224 224 HIS HIS B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 PRO 226 226 226 PRO PRO B . n 
B 1 227 ILE 227 227 227 ILE ILE B . n 
B 1 228 ARG 228 228 228 ARG ARG B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 ASP 230 230 230 ASP ASP B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 TYR 232 232 232 TYR TYR B . n 
B 1 233 ARG 233 233 233 ARG ARG B . n 
B 1 234 GLN 234 234 234 GLN GLN B . n 
B 1 235 ILE 235 235 235 ILE ILE B . n 
B 1 236 LEU 236 236 236 LEU LEU B . n 
B 1 237 GLU 237 237 237 GLU GLU B . n 
B 1 238 GLU 238 238 238 GLU GLU B . n 
B 1 239 PHE 239 239 239 PHE PHE B . n 
B 1 240 ARG 240 240 240 ARG ARG B . n 
B 1 241 SER 241 241 241 SER SER B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 ASN 243 243 243 ASN ASN B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 GLN 245 245 245 GLN GLN B . n 
B 1 246 TYR 246 246 246 TYR TYR B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 ARG 250 250 250 ARG ARG B . n 
B 1 251 SER 251 251 251 SER SER B . n 
B 1 252 SER 252 252 252 SER SER B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 GLY 255 255 255 GLY GLY B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 LEU 259 259 259 LEU LEU B . n 
B 1 260 ASP 260 260 260 ASP ASP B . n 
B 1 261 GLY 261 261 261 GLY GLY B . n 
B 1 262 THR 262 262 262 THR THR B . n 
B 1 263 VAL 263 263 263 VAL VAL B . n 
B 1 264 HIS 264 264 264 HIS HIS B . n 
B 1 265 ASP 265 265 265 ASP ASP B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 GLU 267 267 267 GLU GLU B . n 
B 1 268 PHE 268 268 268 PHE PHE B . n 
B 1 269 GLY 269 269 269 GLY GLY B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 ASN 271 271 271 ASN ASN B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 TYR 273 273 273 TYR TYR B . n 
B 1 274 LYS 274 274 274 LYS LYS B . n 
B 1 275 SER 275 275 275 SER SER B . n 
B 1 276 VAL 276 276 276 VAL VAL B . n 
B 1 277 THR 277 277 277 THR THR B . n 
B 1 278 GLU 278 278 278 GLU GLU B . n 
B 1 279 GLU 279 279 279 GLU GLU B . n 
B 1 280 PHE 280 280 280 PHE PHE B . n 
B 1 281 GLN 281 281 281 GLN GLN B . n 
B 1 282 ARG 282 282 282 ARG ARG B . n 
B 1 283 GLU 283 283 283 GLU GLU B . n 
B 1 284 TYR 284 284 284 TYR TYR B . n 
B 1 285 PRO 285 285 285 PRO PRO B . n 
B 1 286 ASP 286 286 286 ASP ASP B . n 
B 1 287 PHE 287 287 287 PHE PHE B . n 
B 1 288 ILE 288 288 288 ILE ILE B . n 
B 1 289 GLY 289 289 289 GLY GLY B . n 
B 1 290 ALA 290 290 290 ALA ALA B . n 
B 1 291 LYS 291 291 291 LYS LYS B . n 
B 1 292 ILE 292 292 292 ILE ILE B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 LEU 294 294 294 LEU LEU B . n 
B 1 295 SER 295 295 295 SER SER B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 PHE 299 299 299 PHE PHE B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 GLN 302 302 302 GLN GLN B . n 
B 1 303 GLU 303 303 303 GLU GLU B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 ILE 305 305 305 ILE ILE B . n 
B 1 306 LEU 306 306 306 LEU LEU B . n 
B 1 307 ASN 307 307 307 ASN ASN B . n 
B 1 308 GLU 308 308 308 GLU GLU B . n 
B 1 309 VAL 309 309 309 VAL VAL B . n 
B 1 310 LYS 310 310 310 LYS LYS B . n 
B 1 311 ILE 311 311 311 ILE ILE B . n 
B 1 312 ALA 312 312 312 ALA ALA B . n 
B 1 313 MET 313 313 313 MET MET B . n 
B 1 314 ASP 314 314 314 ASP ASP B . n 
B 1 315 LEU 315 315 315 LEU LEU B . n 
B 1 316 HIS 316 316 316 HIS HIS B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 LYS 318 318 318 LYS LYS B . n 
B 1 319 TYR 319 319 319 TYR TYR B . n 
B 1 320 PRO 320 320 320 PRO PRO B . n 
B 1 321 ASP 321 321 321 ASP ASP B . n 
B 1 322 PHE 322 322 322 PHE PHE B . n 
B 1 323 PHE 323 323 323 PHE PHE B . n 
B 1 324 LEU 324 324 324 LEU LEU B . n 
B 1 325 GLY 325 325 325 GLY GLY B . n 
B 1 326 TYR 326 326 326 TYR TYR B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 VAL 329 329 329 VAL VAL B . n 
B 1 330 GLY 330 330 330 GLY GLY B . n 
B 1 331 GLN 331 331 331 GLN GLN B . n 
B 1 332 GLU 332 332 332 GLU GLU B . n 
B 1 333 ASP 333 333 333 ASP ASP B . n 
B 1 334 PRO 334 334 334 PRO PRO B . n 
B 1 335 ASN 335 335 335 ASN ASN B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 SER 337 337 337 SER SER B . n 
B 1 338 LEU 338 338 338 LEU LEU B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 HIS 340 340 340 HIS HIS B . n 
B 1 341 TYR 341 341 341 TYR TYR B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 ALA 344 344 344 ALA ALA B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 LEU 346 346 346 LEU LEU B . n 
B 1 347 TYR 347 347 347 TYR TYR B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 SER 349 349 349 SER SER B . n 
B 1 350 ILE 350 350 350 ILE ILE B . n 
B 1 351 GLN 351 351 351 GLN GLN B . n 
B 1 352 ASN 352 352 352 ASN ASN B . n 
B 1 353 PRO 353 353 353 PRO PRO B . n 
B 1 354 PRO 354 354 354 PRO PRO B . n 
B 1 355 TYR 355 355 355 TYR TYR B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 TYR 359 359 359 TYR TYR B . n 
B 1 360 PHE 360 360 360 PHE PHE B . n 
B 1 361 PHE 361 361 361 PHE PHE B . n 
B 1 362 HIS 362 362 362 HIS HIS B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 ALA 364 364 364 ALA ALA B . n 
B 1 365 GLU 365 365 365 GLU GLU B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 ASN 367 367 367 ASN ASN B . n 
B 1 368 TRP 368 368 368 TRP TRP B . n 
B 1 369 GLN 369 369 369 GLN GLN B . n 
B 1 370 GLU 370 370 370 GLU GLU B . n 
B 1 371 THR 371 371 371 THR THR B . n 
B 1 372 GLU 372 372 372 GLU GLU B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 TYR 375 375 375 TYR TYR B . n 
B 1 376 ASN 376 376 376 ASN ASN B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 ALA 378 378 378 ALA ALA B . n 
B 1 379 ASP 379 379 379 ASP ASP B . n 
B 1 380 ALA 380 380 380 ALA ALA B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 LEU 383 383 383 LEU LEU B . n 
B 1 384 ASN 384 384 384 ASN ASN B . n 
B 1 385 THR 385 385 385 THR THR B . n 
B 1 386 THR 386 386 386 THR THR B . n 
B 1 387 ARG 387 387 387 ARG ARG B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 GLY 389 389 389 GLY GLY B . n 
B 1 390 HIS 390 390 390 HIS HIS B . n 
B 1 391 GLY 391 391 391 GLY GLY B . n 
B 1 392 PHE 392 392 392 PHE PHE B . n 
B 1 393 ALA 393 393 393 ALA ALA B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 ILE 395 395 395 ILE ILE B . n 
B 1 396 LYS 396 396 396 LYS LYS B . n 
B 1 397 HIS 397 397 397 HIS HIS B . n 
B 1 398 PRO 398 398 398 PRO PRO B . n 
B 1 399 ARG 399 399 399 ARG ARG B . n 
B 1 400 PHE 400 400 400 PHE PHE B . n 
B 1 401 THR 401 401 401 THR THR B . n 
B 1 402 GLU 402 402 402 GLU GLU B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 ALA 404 404 404 ALA ALA B . n 
B 1 405 LYS 405 405 405 LYS LYS B . n 
B 1 406 GLU 406 406 406 GLU GLU B . n 
B 1 407 ASN 407 407 407 ASN ASN B . n 
B 1 408 GLY 408 408 408 GLY GLY B . n 
B 1 409 VAL 409 409 409 VAL VAL B . n 
B 1 410 ALA 410 410 410 ALA ALA B . n 
B 1 411 VAL 411 411 411 VAL VAL B . n 
B 1 412 GLU 412 412 412 GLU GLU B . n 
B 1 413 VAL 413 413 413 VAL VAL B . n 
B 1 414 ASN 414 414 414 ASN ASN B . n 
B 1 415 PRO 415 415 415 PRO PRO B . n 
B 1 416 ILE 416 416 416 ILE ILE B . n 
B 1 417 SER 417 417 417 SER SER B . n 
B 1 418 ASN 418 418 418 ASN ASN B . n 
B 1 419 GLN 419 419 419 GLN GLN B . n 
B 1 420 ILE 420 420 420 ILE ILE B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 GLY 422 422 422 GLY GLY B . n 
B 1 423 LEU 423 423 423 LEU LEU B . n 
B 1 424 VAL 424 424 424 VAL VAL B . n 
B 1 425 ARG 425 425 425 ARG ARG B . n 
B 1 426 ASP 426 426 426 ASP ASP B . n 
B 1 427 VAL 427 427 427 VAL VAL B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 ASN 429 429 429 ASN ASN B . n 
B 1 430 HIS 430 430 430 HIS HIS B . n 
B 1 431 ALA 431 431 431 ALA ALA B . n 
B 1 432 LEU 432 432 432 LEU LEU B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 PRO 434 434 434 PRO PRO B . n 
B 1 435 LEU 435 435 435 LEU LEU B . n 
B 1 436 ILE 436 436 436 ILE ILE B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 ASP 438 438 438 ASP ASP B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 TYR 440 440 440 TYR TYR B . n 
B 1 441 PRO 441 441 441 PRO PRO B . n 
B 1 442 ILE 442 442 442 ILE ILE B . n 
B 1 443 VAL 443 443 443 VAL VAL B . n 
B 1 444 ILE 444 444 444 ILE ILE B . n 
B 1 445 SER 445 445 445 SER SER B . n 
B 1 446 SER 446 446 446 SER SER B . n 
B 1 447 ASP 447 447 447 ASP ASP B . n 
B 1 448 ASP 448 448 448 ASP ASP B . n 
B 1 449 PRO 449 449 449 PRO PRO B . n 
B 1 450 GLY 450 450 450 GLY GLY B . n 
B 1 451 ALA 451 451 451 ALA ALA B . n 
B 1 452 TRP 452 452 452 TRP TRP B . n 
B 1 453 GLU 453 453 453 GLU GLU B . n 
B 1 454 ALA 454 454 454 ALA ALA B . n 
B 1 455 SER 455 455 455 SER SER B . n 
B 1 456 PRO 456 456 456 PRO PRO B . n 
B 1 457 LEU 457 457 457 LEU LEU B . n 
B 1 458 SER 458 458 458 SER SER B . n 
B 1 459 HIS 459 459 459 HIS HIS B . n 
B 1 460 ASP 460 460 460 ASP ASP B . n 
B 1 461 PHE 461 461 461 PHE PHE B . n 
B 1 462 TYR 462 462 462 TYR TYR B . n 
B 1 463 VAL 463 463 463 VAL VAL B . n 
B 1 464 ALA 464 464 464 ALA ALA B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 MET 466 466 466 MET MET B . n 
B 1 467 ASP 467 467 467 ASP ASP B . n 
B 1 468 LEU 468 468 468 LEU LEU B . n 
B 1 469 CYS 469 469 469 CYS CYS B . n 
B 1 470 GLY 470 470 470 GLY GLY B . n 
B 1 471 ARG 471 471 471 ARG ARG B . n 
B 1 472 ASP 472 472 472 ASP ASP B . n 
B 1 473 THR 473 473 473 THR THR B . n 
B 1 474 ALA 474 474 474 ALA ALA B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 PHE 477 477 477 PHE PHE B . n 
B 1 478 LEU 478 478 478 LEU LEU B . n 
B 1 479 LYS 479 479 479 LYS LYS B . n 
B 1 480 GLN 480 480 480 GLN GLN B . n 
B 1 481 LEU 481 481 481 LEU LEU B . n 
B 1 482 ALA 482 482 482 ALA ALA B . n 
B 1 483 LEU 483 483 483 LEU LEU B . n 
B 1 484 ASN 484 484 484 ASN ASN B . n 
B 1 485 SER 485 485 485 SER SER B . n 
B 1 486 ILE 486 486 486 ILE ILE B . n 
B 1 487 ARG 487 487 487 ARG ARG B . n 
B 1 488 TYR 488 488 488 TYR TYR B . n 
B 1 489 SER 489 489 489 SER SER B . n 
B 1 490 ALA 490 490 490 ALA ALA B . n 
B 1 491 MET 491 491 491 MET MET B . n 
B 1 492 SER 492 492 492 SER SER B . n 
B 1 493 ASP 493 493 493 ASP ASP B . n 
B 1 494 THR 494 494 494 THR THR B . n 
B 1 495 GLU 495 495 495 GLU GLU B . n 
B 1 496 LYS 496 496 496 LYS LYS B . n 
B 1 497 VAL 497 497 497 VAL VAL B . n 
B 1 498 ALA 498 498 498 ALA ALA B . n 
B 1 499 ALA 499 499 499 ALA ALA B . n 
B 1 500 LYS 500 500 500 LYS LYS B . n 
B 1 501 ALA 501 501 501 ALA ALA B . n 
B 1 502 LYS 502 502 502 LYS LYS B . n 
B 1 503 TRP 503 503 503 TRP TRP B . n 
B 1 504 THR 504 504 504 THR THR B . n 
B 1 505 THR 505 505 505 THR THR B . n 
B 1 506 GLN 506 506 506 GLN GLN B . n 
B 1 507 TRP 507 507 507 TRP TRP B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 LYS 509 509 509 LYS LYS B . n 
B 1 510 PHE 510 510 510 PHE PHE B . n 
B 1 511 VAL 511 511 511 VAL VAL B . n 
B 1 512 LYS 512 512 512 LYS LYS B . n 
B 1 513 THR 513 513 513 THR THR B . n 
B 1 514 SER 514 514 514 SER SER B . n 
B 1 515 VAL 515 515 515 VAL VAL B . n 
B 1 516 GLU 516 516 516 GLU GLU B . n 
B 1 517 GLY 517 517 517 GLY GLY B . n 
B 1 518 LEU 518 518 518 LEU LEU B . n 
B 1 519 LYS 519 519 519 LYS LYS B . n 
B 1 520 PRO 520 520 520 PRO PRO B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 ILE 522 522 ?   ?   ?   B . n 
B 1 523 ASN 523 523 ?   ?   ?   B . n 
B 1 524 ASP 524 524 ?   ?   ?   B . n 
B 1 525 ARG 525 525 ?   ?   ?   B . n 
B 1 526 SER 526 526 ?   ?   ?   B . n 
B 1 527 HIS 527 527 ?   ?   ?   B . n 
B 1 528 HIS 528 528 ?   ?   ?   B . n 
B 1 529 HIS 529 529 ?   ?   ?   B . n 
B 1 530 HIS 530 530 ?   ?   ?   B . n 
B 1 531 HIS 531 531 ?   ?   ?   B . n 
B 1 532 HIS 532 532 ?   ?   ?   B . n 
B 1 533 HIS 533 533 ?   ?   ?   B . n 
B 1 534 HIS 534 534 ?   ?   ?   B . n 
B 1 535 HIS 535 535 ?   ?   ?   B . n 
B 1 536 HIS 536 536 ?   ?   ?   B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 NAG 1 C NAG 1 A NAG 728 n 
C 2 NAG 2 C NAG 2 A NAG 729 n 
C 2 BMA 3 C BMA 3 A BMA 730 n 
C 2 MAN 4 C MAN 4 A MAN 731 n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        DCF 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   DCF 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 3 NAG 1  601 725  NAG NAG A . 
E 3 NAG 1  602 726  NAG NAG A . 
F 3 NAG 1  603 727  NAG NAG A . 
G 4 EDO 1  604 825  EDO EDO A . 
H 4 EDO 1  605 925  EDO EDO A . 
I 4 EDO 1  606 1025 EDO EDO A . 
J 5 ZN  1  607 2    ZN  ZN  A . 
K 6 DCF 1  608 1    DCF DCF A . 
L 3 NAG 1  601 725  NAG NAG B . 
M 3 NAG 1  602 726  NAG NAG B . 
N 3 NAG 1  603 727  NAG NAG B . 
O 3 NAG 1  604 728  NAG NAG B . 
P 4 EDO 1  605 825  EDO EDO B . 
Q 4 EDO 1  606 925  EDO EDO B . 
R 4 EDO 1  607 1025 EDO EDO B . 
S 5 ZN  1  608 1    ZN  ZN  B . 
T 6 DCF 1  609 2    DCF DCF B . 
U 7 HOH 1  701 175  HOH HOH A . 
U 7 HOH 2  702 158  HOH HOH A . 
U 7 HOH 3  703 141  HOH HOH A . 
U 7 HOH 4  704 176  HOH HOH A . 
U 7 HOH 5  705 17   HOH HOH A . 
U 7 HOH 6  706 144  HOH HOH A . 
U 7 HOH 7  707 182  HOH HOH A . 
U 7 HOH 8  708 152  HOH HOH A . 
U 7 HOH 9  709 69   HOH HOH A . 
U 7 HOH 10 710 55   HOH HOH A . 
U 7 HOH 11 711 68   HOH HOH A . 
U 7 HOH 12 712 31   HOH HOH A . 
U 7 HOH 13 713 51   HOH HOH A . 
U 7 HOH 14 714 74   HOH HOH A . 
U 7 HOH 15 715 46   HOH HOH A . 
U 7 HOH 16 716 61   HOH HOH A . 
U 7 HOH 17 717 3    HOH HOH A . 
U 7 HOH 18 718 54   HOH HOH A . 
U 7 HOH 19 719 156  HOH HOH A . 
U 7 HOH 20 720 131  HOH HOH A . 
U 7 HOH 21 721 155  HOH HOH A . 
U 7 HOH 22 722 164  HOH HOH A . 
U 7 HOH 23 723 40   HOH HOH A . 
U 7 HOH 24 724 181  HOH HOH A . 
U 7 HOH 25 725 159  HOH HOH A . 
U 7 HOH 26 726 5    HOH HOH A . 
U 7 HOH 27 727 168  HOH HOH A . 
U 7 HOH 28 728 95   HOH HOH A . 
U 7 HOH 29 729 96   HOH HOH A . 
U 7 HOH 30 730 171  HOH HOH A . 
U 7 HOH 31 731 44   HOH HOH A . 
U 7 HOH 32 732 128  HOH HOH A . 
U 7 HOH 33 733 177  HOH HOH A . 
U 7 HOH 34 734 178  HOH HOH A . 
U 7 HOH 35 735 12   HOH HOH A . 
U 7 HOH 36 736 120  HOH HOH A . 
U 7 HOH 37 737 183  HOH HOH A . 
U 7 HOH 38 738 83   HOH HOH A . 
U 7 HOH 39 739 170  HOH HOH A . 
U 7 HOH 40 740 92   HOH HOH A . 
V 7 HOH 1  701 107  HOH HOH B . 
V 7 HOH 2  702 150  HOH HOH B . 
V 7 HOH 3  703 103  HOH HOH B . 
V 7 HOH 4  704 99   HOH HOH B . 
V 7 HOH 5  705 173  HOH HOH B . 
V 7 HOH 6  706 72   HOH HOH B . 
V 7 HOH 7  707 41   HOH HOH B . 
V 7 HOH 8  708 109  HOH HOH B . 
V 7 HOH 9  709 35   HOH HOH B . 
V 7 HOH 10 710 66   HOH HOH B . 
V 7 HOH 11 711 122  HOH HOH B . 
V 7 HOH 12 712 43   HOH HOH B . 
V 7 HOH 13 713 76   HOH HOH B . 
V 7 HOH 14 714 174  HOH HOH B . 
V 7 HOH 15 715 172  HOH HOH B . 
V 7 HOH 16 716 102  HOH HOH B . 
V 7 HOH 17 717 13   HOH HOH B . 
V 7 HOH 18 718 39   HOH HOH B . 
V 7 HOH 19 719 134  HOH HOH B . 
V 7 HOH 20 720 165  HOH HOH B . 
V 7 HOH 21 721 86   HOH HOH B . 
V 7 HOH 22 722 48   HOH HOH B . 
V 7 HOH 23 723 71   HOH HOH B . 
V 7 HOH 24 724 130  HOH HOH B . 
V 7 HOH 25 725 104  HOH HOH B . 
V 7 HOH 26 726 114  HOH HOH B . 
V 7 HOH 27 727 146  HOH HOH B . 
V 7 HOH 28 728 33   HOH HOH B . 
V 7 HOH 29 729 115  HOH HOH B . 
V 7 HOH 30 730 180  HOH HOH B . 
V 7 HOH 31 731 124  HOH HOH B . 
V 7 HOH 32 732 137  HOH HOH B . 
V 7 HOH 33 733 6    HOH HOH B . 
V 7 HOH 34 734 94   HOH HOH B . 
V 7 HOH 35 735 87   HOH HOH B . 
V 7 HOH 36 736 138  HOH HOH B . 
V 7 HOH 37 737 179  HOH HOH B . 
V 7 HOH 38 738 45   HOH HOH B . 
V 7 HOH 39 739 161  HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? 1.21.2_5419 ? 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000  ? ? ? .           ? 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALEPACK ? ? ? .           ? 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? .           ? 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NTJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     67.349 
_cell.length_a_esd                 ? 
_cell.length_b                     109.609 
_cell.length_b_esd                 ? 
_cell.length_c                     171.555 
_cell.length_c_esd                 ? 
_cell.volume                       1266428.710 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NTJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NTJ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.58 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.31 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.4 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '25% w/v Polyethylene glycol 1,500, 15% Glycerol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-09-20 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 22-ID' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   22-ID 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          27.4 
_reflns.entry_id                                       9NTJ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.28 
_reflns.d_resolution_low                               47.69 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     18753 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           93.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          3.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.123 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.803 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.29 
_reflns_shell.d_res_low                                     3.41 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.1 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1881 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.622 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.331 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               27.23 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NTJ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.28 
_refine.ls_d_res_low                             47.69 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     18669 
_refine.ls_number_reflns_R_free                  934 
_refine.ls_number_reflns_R_work                  17735 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.80 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2125 
_refine.ls_R_factor_R_free                       0.2608 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2099 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 25.0377 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4102 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.28 
_refine_hist.d_res_low                        47.69 
_refine_hist.number_atoms_solvent             82 
_refine_hist.number_atoms_total               8274 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7980 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         212 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0020  ? 8386  ? f_bond_d           ? ? ? 
'X-RAY DIFFRACTION' ? 0.5219  ? 11377 ? f_angle_d          ? ? ? 
'X-RAY DIFFRACTION' ? 0.0412  ? 1283  ? f_chiral_restr     ? ? ? 
'X-RAY DIFFRACTION' ? 0.0037  ? 1447  ? f_plane_restr      ? ? ? 
'X-RAY DIFFRACTION' ? 12.0315 ? 3240  ? f_dihedral_angle_d ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.28 3.45  . . 128 2433 91.40 . . . . 0.2808 . . . . . . . . . . . . . . . 0.3483 
'X-RAY DIFFRACTION' 3.45 3.67  . . 135 2557 95.16 . . . . 0.2456 . . . . . . . . . . . . . . . 0.2780 
'X-RAY DIFFRACTION' 3.67 3.95  . . 134 2548 94.20 . . . . 0.2305 . . . . . . . . . . . . . . . 0.3129 
'X-RAY DIFFRACTION' 3.95 4.35  . . 133 2530 93.90 . . . . 0.1921 . . . . . . . . . . . . . . . 0.2576 
'X-RAY DIFFRACTION' 4.35 4.98  . . 129 2449 89.70 . . . . 0.1657 . . . . . . . . . . . . . . . 0.2364 
'X-RAY DIFFRACTION' 4.98 6.27  . . 136 2582 94.24 . . . . 0.2070 . . . . . . . . . . . . . . . 0.2348 
'X-RAY DIFFRACTION' 6.27 47.69 . . 139 2636 91.10 . . . . 0.1781 . . . . . . . . . . . . . . . 0.1985 
# 
_struct.entry_id                     9NTJ 
_struct.title                        'Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NTJ 
_struct_keywords.text            
;Chimeric Adenosine deaminase growth factor (ADGF) apoenzyme; Hydrolase; Adenosine deaminase; Pentostatin; 2'-deoxycoformycin, HYDROLASE
;
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 5 ? 
K N N 6 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 3 ? 
P N N 4 ? 
Q N N 4 ? 
R N N 4 ? 
S N N 5 ? 
T N N 6 ? 
U N N 7 ? 
V N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP AGSA_APLCA P15287 ? 1 
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHD
;
1   
2 PDB 9NTJ       9NTJ   ? 1 ? 121 
3 UNP AGSA_APLCA P15287 ? 1 
;GFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYPDFFLGYDLVGQEDP
NFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRFTELAKENGVAVEVN
PISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQLALNSIRYSAMSDT
EKVAAKAKWTTQWDKFVKTSVEGLKPHINDRS
;
254 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NTJ A 1   ? 120 ? P15287 1   ? 120 ? 1   120 
2 2 9NTJ A 121 ? 254 ? 9NTJ   121 ? 254 ? 121 254 
3 3 9NTJ A 255 ? 526 ? P15287 254 ? 525 ? 255 526 
4 1 9NTJ B 1   ? 120 ? P15287 1   ? 120 ? 1   120 
5 2 9NTJ B 121 ? 254 ? 9NTJ   121 ? 254 ? 121 254 
6 3 9NTJ B 255 ? 526 ? P15287 254 ? 525 ? 255 526 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9NTJ HIS A 527 ? UNP P15287 ? ? 'expression tag' 527 1  
3 9NTJ HIS A 528 ? UNP P15287 ? ? 'expression tag' 528 2  
3 9NTJ HIS A 529 ? UNP P15287 ? ? 'expression tag' 529 3  
3 9NTJ HIS A 530 ? UNP P15287 ? ? 'expression tag' 530 4  
3 9NTJ HIS A 531 ? UNP P15287 ? ? 'expression tag' 531 5  
3 9NTJ HIS A 532 ? UNP P15287 ? ? 'expression tag' 532 6  
3 9NTJ HIS A 533 ? UNP P15287 ? ? 'expression tag' 533 7  
3 9NTJ HIS A 534 ? UNP P15287 ? ? 'expression tag' 534 8  
3 9NTJ HIS A 535 ? UNP P15287 ? ? 'expression tag' 535 9  
3 9NTJ HIS A 536 ? UNP P15287 ? ? 'expression tag' 536 10 
6 9NTJ HIS B 527 ? UNP P15287 ? ? 'expression tag' 527 11 
6 9NTJ HIS B 528 ? UNP P15287 ? ? 'expression tag' 528 12 
6 9NTJ HIS B 529 ? UNP P15287 ? ? 'expression tag' 529 13 
6 9NTJ HIS B 530 ? UNP P15287 ? ? 'expression tag' 530 14 
6 9NTJ HIS B 531 ? UNP P15287 ? ? 'expression tag' 531 15 
6 9NTJ HIS B 532 ? UNP P15287 ? ? 'expression tag' 532 16 
6 9NTJ HIS B 533 ? UNP P15287 ? ? 'expression tag' 533 17 
6 9NTJ HIS B 534 ? UNP P15287 ? ? 'expression tag' 534 18 
6 9NTJ HIS B 535 ? UNP P15287 ? ? 'expression tag' 535 19 
6 9NTJ HIS B 536 ? UNP P15287 ? ? 'expression tag' 536 20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 11730 ? 
1 MORE         -41   ? 
1 'SSA (A^2)'  37500 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 29  ? SER A 47  ? THR A 29  SER A 47  1 ? 19 
HELX_P HELX_P2  AA2 THR A 57  ? ASN A 81  ? THR A 57  ASN A 81  1 ? 25 
HELX_P HELX_P3  AA3 TYR A 85  ? ALA A 89  ? TYR A 85  ALA A 89  5 ? 5  
HELX_P HELX_P4  AA4 SER A 90  ? THR A 100 ? SER A 90  THR A 100 1 ? 11 
HELX_P HELX_P5  AA5 THR A 101 ? MET A 110 ? THR A 101 MET A 110 1 ? 10 
HELX_P HELX_P6  AA6 THR A 121 ? SER A 123 ? THR A 121 SER A 123 5 ? 3  
HELX_P HELX_P7  AA7 ARG A 125 ? ASN A 132 ? ARG A 125 ASN A 132 1 ? 8  
HELX_P HELX_P8  AA8 ALA A 133 ? ARG A 136 ? ALA A 133 ARG A 136 5 ? 4  
HELX_P HELX_P9  AA9 VAL A 169 ? GLY A 177 ? VAL A 169 GLY A 177 1 ? 9  
HELX_P HELX_P10 AB1 ASP A 178 ? ASN A 189 ? ASP A 178 ASN A 189 1 ? 12 
HELX_P HELX_P11 AB2 ASP A 196 ? TYR A 201 ? ASP A 196 TYR A 201 1 ? 6  
HELX_P HELX_P12 AB3 SER A 203 ? TYR A 223 ? SER A 203 TYR A 223 1 ? 21 
HELX_P HELX_P13 AB4 HIS A 224 ? ASP A 242 ? HIS A 224 ASP A 242 1 ? 19 
HELX_P HELX_P14 AB5 ASP A 265 ? TYR A 284 ? ASP A 265 TYR A 284 1 ? 20 
HELX_P HELX_P15 AB6 SER A 301 ? TYR A 319 ? SER A 301 TYR A 319 1 ? 19 
HELX_P HELX_P16 AB7 LEU A 338 ? HIS A 340 ? LEU A 338 HIS A 340 5 ? 3  
HELX_P HELX_P17 AB8 TYR A 341 ? TYR A 347 ? TYR A 341 TYR A 347 1 ? 7  
HELX_P HELX_P18 AB9 TYR A 375 ? LEU A 383 ? TYR A 375 LEU A 383 1 ? 9  
HELX_P HELX_P19 AC1 HIS A 397 ? GLY A 408 ? HIS A 397 GLY A 408 1 ? 12 
HELX_P HELX_P20 AC2 ASN A 414 ? LEU A 421 ? ASN A 414 LEU A 421 1 ? 8  
HELX_P HELX_P21 AC3 ASP A 426 ? HIS A 430 ? ASP A 426 HIS A 430 5 ? 5  
HELX_P HELX_P22 AC4 LEU A 432 ? ASP A 438 ? LEU A 432 ASP A 438 1 ? 7  
HELX_P HELX_P23 AC5 PRO A 449 ? GLU A 453 ? PRO A 449 GLU A 453 5 ? 5  
HELX_P HELX_P24 AC6 LEU A 457 ? LEU A 468 ? LEU A 457 LEU A 468 1 ? 12 
HELX_P HELX_P25 AC7 ALA A 474 ? TYR A 488 ? ALA A 474 TYR A 488 1 ? 15 
HELX_P HELX_P26 AC8 SER A 492 ? LYS A 519 ? SER A 492 LYS A 519 1 ? 28 
HELX_P HELX_P27 AC9 THR B 29  ? SER B 47  ? THR B 29  SER B 47  1 ? 19 
HELX_P HELX_P28 AD1 THR B 57  ? ASN B 81  ? THR B 57  ASN B 81  1 ? 25 
HELX_P HELX_P29 AD2 TYR B 85  ? ALA B 89  ? TYR B 85  ALA B 89  5 ? 5  
HELX_P HELX_P30 AD3 SER B 90  ? THR B 100 ? SER B 90  THR B 100 1 ? 11 
HELX_P HELX_P31 AD4 THR B 101 ? MET B 110 ? THR B 101 MET B 110 1 ? 10 
HELX_P HELX_P32 AD5 THR B 121 ? SER B 123 ? THR B 121 SER B 123 5 ? 3  
HELX_P HELX_P33 AD6 ARG B 125 ? ASN B 132 ? ARG B 125 ASN B 132 1 ? 8  
HELX_P HELX_P34 AD7 ALA B 133 ? ARG B 136 ? ALA B 133 ARG B 136 5 ? 4  
HELX_P HELX_P35 AD8 VAL B 169 ? GLY B 177 ? VAL B 169 GLY B 177 1 ? 9  
HELX_P HELX_P36 AD9 ASP B 178 ? SER B 191 ? ASP B 178 SER B 191 1 ? 14 
HELX_P HELX_P37 AE1 ASP B 196 ? TYR B 201 ? ASP B 196 TYR B 201 1 ? 6  
HELX_P HELX_P38 AE2 SER B 203 ? TYR B 223 ? SER B 203 TYR B 223 1 ? 21 
HELX_P HELX_P39 AE3 HIS B 224 ? ASP B 242 ? HIS B 224 ASP B 242 1 ? 19 
HELX_P HELX_P40 AE4 ASP B 265 ? TYR B 284 ? ASP B 265 TYR B 284 1 ? 20 
HELX_P HELX_P41 AE5 SER B 301 ? TYR B 319 ? SER B 301 TYR B 319 1 ? 19 
HELX_P HELX_P42 AE6 LEU B 338 ? HIS B 340 ? LEU B 338 HIS B 340 5 ? 3  
HELX_P HELX_P43 AE7 TYR B 341 ? TYR B 347 ? TYR B 341 TYR B 347 1 ? 7  
HELX_P HELX_P44 AE8 THR B 371 ? LEU B 383 ? THR B 371 LEU B 383 1 ? 13 
HELX_P HELX_P45 AE9 HIS B 397 ? GLY B 408 ? HIS B 397 GLY B 408 1 ? 12 
HELX_P HELX_P46 AF1 ASN B 414 ? LEU B 421 ? ASN B 414 LEU B 421 1 ? 8  
HELX_P HELX_P47 AF2 ASP B 426 ? HIS B 430 ? ASP B 426 HIS B 430 5 ? 5  
HELX_P HELX_P48 AF3 LEU B 432 ? ASP B 438 ? LEU B 432 ASP B 438 1 ? 7  
HELX_P HELX_P49 AF4 PRO B 449 ? GLU B 453 ? PRO B 449 GLU B 453 5 ? 5  
HELX_P HELX_P50 AF5 LEU B 457 ? LEU B 468 ? LEU B 457 LEU B 468 1 ? 12 
HELX_P HELX_P51 AF6 ALA B 474 ? TYR B 488 ? ALA B 474 TYR B 488 1 ? 15 
HELX_P HELX_P52 AF7 SER B 492 ? LYS B 519 ? SER B 492 LYS B 519 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 142 SG  ? ? ? 1_555 A CYS 164 SG ? ? A CYS 142 A CYS 164 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf2  disulf ?    ? B CYS 142 SG  ? ? ? 1_555 B CYS 164 SG ? ? B CYS 142 B CYS 164 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
covale1  covale one  ? A ASN 81  ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 81  A NAG 602 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale2  covale one  ? A ASN 132 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 132 A NAG 601 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale3  covale one  ? A ASN 189 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 189 A NAG 603 1_555 ? ? ? ? ? ? ? 1.435 ? N-Glycosylation 
covale4  covale one  ? A ASN 384 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 384 C NAG 1   1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale5  covale one  ? B ASN 81  ND2 ? ? ? 1_555 M NAG .   C1 ? ? B ASN 81  B NAG 602 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale6  covale one  ? B ASN 132 ND2 ? ? ? 1_555 L NAG .   C1 ? ? B ASN 132 B NAG 601 1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale7  covale one  ? B ASN 189 ND2 ? ? ? 1_555 N NAG .   C1 ? ? B ASN 189 B NAG 603 1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale8  covale one  ? B ASN 384 ND2 ? ? ? 1_555 O NAG .   C1 ? ? B ASN 384 B NAG 604 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale9  covale both ? C NAG .   O4  ? ? ? 1_555 C NAG .   C1 ? ? C NAG 1   C NAG 2   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale10 covale both ? C NAG .   O4  ? ? ? 1_555 C BMA .   C1 ? ? C NAG 2   C BMA 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale11 covale both ? C BMA .   O6  ? ? ? 1_555 C MAN .   C1 ? ? C BMA 3   C MAN 4   1_555 ? ? ? ? ? ? ? 1.453 ? ?               
metalc1  metalc ?    ? A HIS 117 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? A HIS 117 A ZN  607 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
metalc2  metalc ?    ? A HIS 119 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? A HIS 119 A ZN  607 1_555 ? ? ? ? ? ? ? 2.060 ? ?               
metalc3  metalc ?    ? A HIS 362 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? A HIS 362 A ZN  607 1_555 ? ? ? ? ? ? ? 2.120 ? ?               
metalc4  metalc ?    ? A ASP 447 OD1 ? ? ? 1_555 J ZN  .   ZN ? ? A ASP 447 A ZN  607 1_555 ? ? ? ? ? ? ? 2.059 ? ?               
metalc5  metalc ?    ? J ZN  .   ZN  ? ? ? 1_555 K DCF .   O8 ? ? A ZN  607 A DCF 608 1_555 ? ? ? ? ? ? ? 2.015 ? ?               
metalc6  metalc ?    ? B HIS 117 NE2 ? ? ? 1_555 S ZN  .   ZN ? ? B HIS 117 B ZN  608 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
metalc7  metalc ?    ? B HIS 119 NE2 ? ? ? 1_555 S ZN  .   ZN ? ? B HIS 119 B ZN  608 1_555 ? ? ? ? ? ? ? 2.061 ? ?               
metalc8  metalc ?    ? B HIS 362 NE2 ? ? ? 1_555 S ZN  .   ZN ? ? B HIS 362 B ZN  608 1_555 ? ? ? ? ? ? ? 2.156 ? ?               
metalc9  metalc ?    ? B ASP 447 OD1 ? ? ? 1_555 S ZN  .   ZN ? ? B ASP 447 B ZN  608 1_555 ? ? ? ? ? ? ? 2.084 ? ?               
metalc10 metalc ?    ? S ZN  .   ZN  ? ? ? 1_555 T DCF .   O8 ? ? B ZN  608 B DCF 609 1_555 ? ? ? ? ? ? ? 1.849 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 NE2 ? A HIS 119 ? A HIS 119 ? 1_555 127.7 ? 
2  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 NE2 ? A HIS 362 ? A HIS 362 ? 1_555 84.8  ? 
3  NE2 ? A HIS 119 ? A HIS 119 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 NE2 ? A HIS 362 ? A HIS 362 ? 1_555 106.4 ? 
4  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 82.6  ? 
5  NE2 ? A HIS 119 ? A HIS 119 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 90.7  ? 
6  NE2 ? A HIS 362 ? A HIS 362 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 162.7 ? 
7  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 O8  ? K DCF .   ? A DCF 608 ? 1_555 126.4 ? 
8  NE2 ? A HIS 119 ? A HIS 119 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 O8  ? K DCF .   ? A DCF 608 ? 1_555 105.1 ? 
9  NE2 ? A HIS 362 ? A HIS 362 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 O8  ? K DCF .   ? A DCF 608 ? 1_555 88.9  ? 
10 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 ZN ? J ZN . ? A ZN 607 ? 1_555 O8  ? K DCF .   ? A DCF 608 ? 1_555 89.1  ? 
11 NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 128.0 ? 
12 NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 87.3  ? 
13 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 111.9 ? 
14 NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 80.4  ? 
15 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 93.4  ? 
16 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 154.2 ? 
17 NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 O8  ? T DCF .   ? B DCF 609 ? 1_555 123.5 ? 
18 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 O8  ? T DCF .   ? B DCF 609 ? 1_555 104.9 ? 
19 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 O8  ? T DCF .   ? B DCF 609 ? 1_555 90.1  ? 
20 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 ZN ? S ZN . ? B ZN 608 ? 1_555 O8  ? T DCF .   ? B DCF 609 ? 1_555 78.3  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG C .   ? ASN A 384 ? NAG C 1   ? 1_555 ASN A 384 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG D .   ? ASN A 132 ? NAG A 601 ? 1_555 ASN A 132 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG E .   ? ASN A 81  ? NAG A 602 ? 1_555 ASN A 81  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG F .   ? ASN A 189 ? NAG A 603 ? 1_555 ASN A 189 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG L .   ? ASN B 132 ? NAG B 601 ? 1_555 ASN B 132 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG M .   ? ASN B 81  ? NAG B 602 ? 1_555 ASN B 81  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG N .   ? ASN B 189 ? NAG B 603 ? 1_555 ASN B 189 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG O .   ? ASN B 384 ? NAG B 604 ? 1_555 ASN B 384 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  CYS A 142 ? CYS A 164 ? CYS A 142 ? 1_555 CYS A 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS B 142 ? CYS B 164 ? CYS B 142 ? 1_555 CYS B 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 352 A . ? ASN 352 A PRO 353 A ? PRO 353 A 1 1.70 
2 ASN 352 B . ? ASN 352 B PRO 353 B ? PRO 353 B 1 0.23 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 113 ? HIS A 119 ? GLY A 113 HIS A 119 
AA1 2 VAL A 244 ? SER A 251 ? VAL A 244 SER A 251 
AA1 3 GLY A 289 ? LEU A 297 ? GLY A 289 LEU A 297 
AA1 4 PHE A 323 ? VAL A 329 ? PHE A 323 VAL A 329 
AA2 1 VAL A 149 ? VAL A 153 ? VAL A 149 VAL A 153 
AA2 2 VAL A 139 ? MET A 143 ? VAL A 139 MET A 143 
AA2 3 LYS A 167 ? LEU A 168 ? LYS A 167 LEU A 168 
AA3 1 HIS A 362 ? ALA A 363 ? HIS A 362 ALA A 363 
AA3 2 ARG A 387 ? HIS A 390 ? ARG A 387 HIS A 390 
AA3 3 ALA A 410 ? VAL A 413 ? ALA A 410 VAL A 413 
AA3 4 ILE A 442 ? ILE A 444 ? ILE A 442 ILE A 444 
AA4 1 GLY B 113 ? HIS B 119 ? GLY B 113 HIS B 119 
AA4 2 VAL B 244 ? SER B 251 ? VAL B 244 SER B 251 
AA4 3 GLY B 289 ? LEU B 297 ? GLY B 289 LEU B 297 
AA4 4 PHE B 323 ? VAL B 329 ? PHE B 323 VAL B 329 
AA5 1 VAL B 149 ? VAL B 153 ? VAL B 149 VAL B 153 
AA5 2 VAL B 139 ? MET B 143 ? VAL B 139 MET B 143 
AA5 3 LYS B 167 ? LEU B 168 ? LYS B 167 LEU B 168 
AA6 1 HIS B 362 ? ALA B 363 ? HIS B 362 ALA B 363 
AA6 2 ARG B 387 ? HIS B 390 ? ARG B 387 HIS B 390 
AA6 3 ALA B 410 ? VAL B 413 ? ALA B 410 VAL B 413 
AA6 4 ILE B 442 ? ILE B 444 ? ILE B 442 ILE B 444 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 118 ? N LEU A 118 O ARG A 250 ? O ARG A 250 
AA1 2 3 N SER A 251 ? N SER A 251 O ILE A 293 ? O ILE A 293 
AA1 3 4 N GLY A 296 ? N GLY A 296 O VAL A 329 ? O VAL A 329 
AA2 1 2 O THR A 152 ? O THR A 152 N TYR A 140 ? N TYR A 140 
AA2 2 3 N MET A 141 ? N MET A 141 O LYS A 167 ? O LYS A 167 
AA3 1 2 N ALA A 363 ? N ALA A 363 O GLY A 389 ? O GLY A 389 
AA3 2 3 N VAL A 388 ? N VAL A 388 O GLU A 412 ? O GLU A 412 
AA3 3 4 N VAL A 413 ? N VAL A 413 O VAL A 443 ? O VAL A 443 
AA4 1 2 N LEU B 118 ? N LEU B 118 O ARG B 250 ? O ARG B 250 
AA4 2 3 N SER B 251 ? N SER B 251 O ILE B 293 ? O ILE B 293 
AA4 3 4 N GLY B 296 ? N GLY B 296 O VAL B 329 ? O VAL B 329 
AA5 1 2 O THR B 152 ? O THR B 152 N TYR B 140 ? N TYR B 140 
AA5 2 3 N MET B 141 ? N MET B 141 O LYS B 167 ? O LYS B 167 
AA6 1 2 N ALA B 363 ? N ALA B 363 O GLY B 389 ? O GLY B 389 
AA6 2 3 N VAL B 388 ? N VAL B 388 O GLU B 412 ? O GLU B 412 
AA6 3 4 N VAL B 411 ? N VAL B 411 O VAL B 443 ? O VAL B 443 
# 
_pdbx_entry_details.entry_id                   9NTJ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 122 ? ? -140.52 41.51   
2  1 THR A 156 ? ? -95.33  59.44   
3  1 PRO A 202 ? ? -83.58  45.76   
4  1 LEU A 253 ? ? 72.73   -8.76   
5  1 HIS A 390 ? ? 70.42   -76.25  
6  1 ASP A 447 ? ? 56.63   -108.80 
7  1 ASP A 472 ? ? -97.12  30.29   
8  1 ALA B 122 ? ? -141.70 41.39   
9  1 PRO B 202 ? ? -82.50  46.75   
10 1 LEU B 253 ? ? 72.62   -8.57   
11 1 HIS B 390 ? ? 69.37   -76.91  
12 1 ASP B 447 ? ? 58.56   -109.03 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A SER 2   ? A SER 2   
3  1 Y 1 A SER 3   ? A SER 3   
4  1 Y 1 A PHE 4   ? A PHE 4   
5  1 Y 1 A SER 5   ? A SER 5   
6  1 Y 1 A THR 6   ? A THR 6   
7  1 Y 1 A HIS 7   ? A HIS 7   
8  1 Y 1 A ASN 8   ? A ASN 8   
9  1 Y 1 A PHE 9   ? A PHE 9   
10 1 Y 1 A VAL 10  ? A VAL 10  
11 1 Y 1 A ALA 11  ? A ALA 11  
12 1 Y 1 A ILE 12  ? A ILE 12  
13 1 Y 1 A ALA 13  ? A ALA 13  
14 1 Y 1 A THR 14  ? A THR 14  
15 1 Y 1 A PHE 15  ? A PHE 15  
16 1 Y 1 A VAL 16  ? A VAL 16  
17 1 Y 1 A CYS 17  ? A CYS 17  
18 1 Y 1 A TRP 18  ? A TRP 18  
19 1 Y 1 A PHE 19  ? A PHE 19  
20 1 Y 1 A CYS 20  ? A CYS 20  
21 1 Y 1 A CYS 21  ? A CYS 21  
22 1 Y 1 A LEU 22  ? A LEU 22  
23 1 Y 1 A ALA 23  ? A ALA 23  
24 1 Y 1 A THR 24  ? A THR 24  
25 1 Y 1 A ALA 25  ? A ALA 25  
26 1 Y 1 A ALA 26  ? A ALA 26  
27 1 Y 1 A PRO 27  ? A PRO 27  
28 1 Y 1 A ILE 522 ? A ILE 522 
29 1 Y 1 A ASN 523 ? A ASN 523 
30 1 Y 1 A ASP 524 ? A ASP 524 
31 1 Y 1 A ARG 525 ? A ARG 525 
32 1 Y 1 A SER 526 ? A SER 526 
33 1 Y 1 A HIS 527 ? A HIS 527 
34 1 Y 1 A HIS 528 ? A HIS 528 
35 1 Y 1 A HIS 529 ? A HIS 529 
36 1 Y 1 A HIS 530 ? A HIS 530 
37 1 Y 1 A HIS 531 ? A HIS 531 
38 1 Y 1 A HIS 532 ? A HIS 532 
39 1 Y 1 A HIS 533 ? A HIS 533 
40 1 Y 1 A HIS 534 ? A HIS 534 
41 1 Y 1 A HIS 535 ? A HIS 535 
42 1 Y 1 A HIS 536 ? A HIS 536 
43 1 Y 1 B MET 1   ? B MET 1   
44 1 Y 1 B SER 2   ? B SER 2   
45 1 Y 1 B SER 3   ? B SER 3   
46 1 Y 1 B PHE 4   ? B PHE 4   
47 1 Y 1 B SER 5   ? B SER 5   
48 1 Y 1 B THR 6   ? B THR 6   
49 1 Y 1 B HIS 7   ? B HIS 7   
50 1 Y 1 B ASN 8   ? B ASN 8   
51 1 Y 1 B PHE 9   ? B PHE 9   
52 1 Y 1 B VAL 10  ? B VAL 10  
53 1 Y 1 B ALA 11  ? B ALA 11  
54 1 Y 1 B ILE 12  ? B ILE 12  
55 1 Y 1 B ALA 13  ? B ALA 13  
56 1 Y 1 B THR 14  ? B THR 14  
57 1 Y 1 B PHE 15  ? B PHE 15  
58 1 Y 1 B VAL 16  ? B VAL 16  
59 1 Y 1 B CYS 17  ? B CYS 17  
60 1 Y 1 B TRP 18  ? B TRP 18  
61 1 Y 1 B PHE 19  ? B PHE 19  
62 1 Y 1 B CYS 20  ? B CYS 20  
63 1 Y 1 B CYS 21  ? B CYS 21  
64 1 Y 1 B LEU 22  ? B LEU 22  
65 1 Y 1 B ALA 23  ? B ALA 23  
66 1 Y 1 B THR 24  ? B THR 24  
67 1 Y 1 B ALA 25  ? B ALA 25  
68 1 Y 1 B ALA 26  ? B ALA 26  
69 1 Y 1 B PRO 27  ? B PRO 27  
70 1 Y 1 B ILE 522 ? B ILE 522 
71 1 Y 1 B ASN 523 ? B ASN 523 
72 1 Y 1 B ASP 524 ? B ASP 524 
73 1 Y 1 B ARG 525 ? B ARG 525 
74 1 Y 1 B SER 526 ? B SER 526 
75 1 Y 1 B HIS 527 ? B HIS 527 
76 1 Y 1 B HIS 528 ? B HIS 528 
77 1 Y 1 B HIS 529 ? B HIS 529 
78 1 Y 1 B HIS 530 ? B HIS 530 
79 1 Y 1 B HIS 531 ? B HIS 531 
80 1 Y 1 B HIS 532 ? B HIS 532 
81 1 Y 1 B HIS 533 ? B HIS 533 
82 1 Y 1 B HIS 534 ? B HIS 534 
83 1 Y 1 B HIS 535 ? B HIS 535 
84 1 Y 1 B HIS 536 ? B HIS 536 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
BMA C1   C  N R 74  
BMA C2   C  N S 75  
BMA C3   C  N S 76  
BMA C4   C  N S 77  
BMA C5   C  N R 78  
BMA C6   C  N N 79  
BMA O1   O  N N 80  
BMA O2   O  N N 81  
BMA O3   O  N N 82  
BMA O4   O  N N 83  
BMA O5   O  N N 84  
BMA O6   O  N N 85  
BMA H1   H  N N 86  
BMA H2   H  N N 87  
BMA H3   H  N N 88  
BMA H4   H  N N 89  
BMA H5   H  N N 90  
BMA H61  H  N N 91  
BMA H62  H  N N 92  
BMA HO1  H  N N 93  
BMA HO2  H  N N 94  
BMA HO3  H  N N 95  
BMA HO4  H  N N 96  
BMA HO6  H  N N 97  
CYS N    N  N N 98  
CYS CA   C  N R 99  
CYS C    C  N N 100 
CYS O    O  N N 101 
CYS CB   C  N N 102 
CYS SG   S  N N 103 
CYS OXT  O  N N 104 
CYS H    H  N N 105 
CYS H2   H  N N 106 
CYS HA   H  N N 107 
CYS HB2  H  N N 108 
CYS HB3  H  N N 109 
CYS HG   H  N N 110 
CYS HXT  H  N N 111 
DCF N1   N  Y N 112 
DCF C2   C  Y N 113 
DCF N3   N  Y N 114 
DCF C9   C  Y N 115 
DCF C10  C  Y N 116 
DCF N4   N  N N 117 
DCF C5   C  N N 118 
DCF N6   N  N N 119 
DCF C7   C  N N 120 
DCF C8   C  N R 121 
DCF O8   O  N N 122 
DCF C2S  C  N N 123 
DCF C3S  C  N S 124 
DCF O3S  O  N N 125 
DCF O5S  O  N N 126 
DCF C5S  C  N N 127 
DCF C4S  C  N R 128 
DCF O4S  O  N N 129 
DCF C1S  C  N R 130 
DCF H2   H  N N 131 
DCF H5   H  N N 132 
DCF HN6  H  N N 133 
DCF H71  H  N N 134 
DCF H72  H  N N 135 
DCF H8   H  N N 136 
DCF HO8  H  N N 137 
DCF H2S1 H  N N 138 
DCF H2S2 H  N N 139 
DCF H3S  H  N N 140 
DCF HO3  H  N N 141 
DCF HO5  H  N N 142 
DCF H5S1 H  N N 143 
DCF H5S2 H  N N 144 
DCF H4S  H  N N 145 
DCF H1S  H  N N 146 
EDO C1   C  N N 147 
EDO O1   O  N N 148 
EDO C2   C  N N 149 
EDO O2   O  N N 150 
EDO H11  H  N N 151 
EDO H12  H  N N 152 
EDO HO1  H  N N 153 
EDO H21  H  N N 154 
EDO H22  H  N N 155 
EDO HO2  H  N N 156 
GLN N    N  N N 157 
GLN CA   C  N S 158 
GLN C    C  N N 159 
GLN O    O  N N 160 
GLN CB   C  N N 161 
GLN CG   C  N N 162 
GLN CD   C  N N 163 
GLN OE1  O  N N 164 
GLN NE2  N  N N 165 
GLN OXT  O  N N 166 
GLN H    H  N N 167 
GLN H2   H  N N 168 
GLN HA   H  N N 169 
GLN HB2  H  N N 170 
GLN HB3  H  N N 171 
GLN HG2  H  N N 172 
GLN HG3  H  N N 173 
GLN HE21 H  N N 174 
GLN HE22 H  N N 175 
GLN HXT  H  N N 176 
GLU N    N  N N 177 
GLU CA   C  N S 178 
GLU C    C  N N 179 
GLU O    O  N N 180 
GLU CB   C  N N 181 
GLU CG   C  N N 182 
GLU CD   C  N N 183 
GLU OE1  O  N N 184 
GLU OE2  O  N N 185 
GLU OXT  O  N N 186 
GLU H    H  N N 187 
GLU H2   H  N N 188 
GLU HA   H  N N 189 
GLU HB2  H  N N 190 
GLU HB3  H  N N 191 
GLU HG2  H  N N 192 
GLU HG3  H  N N 193 
GLU HE2  H  N N 194 
GLU HXT  H  N N 195 
GLY N    N  N N 196 
GLY CA   C  N N 197 
GLY C    C  N N 198 
GLY O    O  N N 199 
GLY OXT  O  N N 200 
GLY H    H  N N 201 
GLY H2   H  N N 202 
GLY HA2  H  N N 203 
GLY HA3  H  N N 204 
GLY HXT  H  N N 205 
HIS N    N  N N 206 
HIS CA   C  N S 207 
HIS C    C  N N 208 
HIS O    O  N N 209 
HIS CB   C  N N 210 
HIS CG   C  Y N 211 
HIS ND1  N  Y N 212 
HIS CD2  C  Y N 213 
HIS CE1  C  Y N 214 
HIS NE2  N  Y N 215 
HIS OXT  O  N N 216 
HIS H    H  N N 217 
HIS H2   H  N N 218 
HIS HA   H  N N 219 
HIS HB2  H  N N 220 
HIS HB3  H  N N 221 
HIS HD1  H  N N 222 
HIS HD2  H  N N 223 
HIS HE1  H  N N 224 
HIS HE2  H  N N 225 
HIS HXT  H  N N 226 
HOH O    O  N N 227 
HOH H1   H  N N 228 
HOH H2   H  N N 229 
ILE N    N  N N 230 
ILE CA   C  N S 231 
ILE C    C  N N 232 
ILE O    O  N N 233 
ILE CB   C  N S 234 
ILE CG1  C  N N 235 
ILE CG2  C  N N 236 
ILE CD1  C  N N 237 
ILE OXT  O  N N 238 
ILE H    H  N N 239 
ILE H2   H  N N 240 
ILE HA   H  N N 241 
ILE HB   H  N N 242 
ILE HG12 H  N N 243 
ILE HG13 H  N N 244 
ILE HG21 H  N N 245 
ILE HG22 H  N N 246 
ILE HG23 H  N N 247 
ILE HD11 H  N N 248 
ILE HD12 H  N N 249 
ILE HD13 H  N N 250 
ILE HXT  H  N N 251 
LEU N    N  N N 252 
LEU CA   C  N S 253 
LEU C    C  N N 254 
LEU O    O  N N 255 
LEU CB   C  N N 256 
LEU CG   C  N N 257 
LEU CD1  C  N N 258 
LEU CD2  C  N N 259 
LEU OXT  O  N N 260 
LEU H    H  N N 261 
LEU H2   H  N N 262 
LEU HA   H  N N 263 
LEU HB2  H  N N 264 
LEU HB3  H  N N 265 
LEU HG   H  N N 266 
LEU HD11 H  N N 267 
LEU HD12 H  N N 268 
LEU HD13 H  N N 269 
LEU HD21 H  N N 270 
LEU HD22 H  N N 271 
LEU HD23 H  N N 272 
LEU HXT  H  N N 273 
LYS N    N  N N 274 
LYS CA   C  N S 275 
LYS C    C  N N 276 
LYS O    O  N N 277 
LYS CB   C  N N 278 
LYS CG   C  N N 279 
LYS CD   C  N N 280 
LYS CE   C  N N 281 
LYS NZ   N  N N 282 
LYS OXT  O  N N 283 
LYS H    H  N N 284 
LYS H2   H  N N 285 
LYS HA   H  N N 286 
LYS HB2  H  N N 287 
LYS HB3  H  N N 288 
LYS HG2  H  N N 289 
LYS HG3  H  N N 290 
LYS HD2  H  N N 291 
LYS HD3  H  N N 292 
LYS HE2  H  N N 293 
LYS HE3  H  N N 294 
LYS HZ1  H  N N 295 
LYS HZ2  H  N N 296 
LYS HZ3  H  N N 297 
LYS HXT  H  N N 298 
MAN C1   C  N S 299 
MAN C2   C  N S 300 
MAN C3   C  N S 301 
MAN C4   C  N S 302 
MAN C5   C  N R 303 
MAN C6   C  N N 304 
MAN O1   O  N N 305 
MAN O2   O  N N 306 
MAN O3   O  N N 307 
MAN O4   O  N N 308 
MAN O5   O  N N 309 
MAN O6   O  N N 310 
MAN H1   H  N N 311 
MAN H2   H  N N 312 
MAN H3   H  N N 313 
MAN H4   H  N N 314 
MAN H5   H  N N 315 
MAN H61  H  N N 316 
MAN H62  H  N N 317 
MAN HO1  H  N N 318 
MAN HO2  H  N N 319 
MAN HO3  H  N N 320 
MAN HO4  H  N N 321 
MAN HO6  H  N N 322 
MET N    N  N N 323 
MET CA   C  N S 324 
MET C    C  N N 325 
MET O    O  N N 326 
MET CB   C  N N 327 
MET CG   C  N N 328 
MET SD   S  N N 329 
MET CE   C  N N 330 
MET OXT  O  N N 331 
MET H    H  N N 332 
MET H2   H  N N 333 
MET HA   H  N N 334 
MET HB2  H  N N 335 
MET HB3  H  N N 336 
MET HG2  H  N N 337 
MET HG3  H  N N 338 
MET HE1  H  N N 339 
MET HE2  H  N N 340 
MET HE3  H  N N 341 
MET HXT  H  N N 342 
NAG C1   C  N R 343 
NAG C2   C  N R 344 
NAG C3   C  N R 345 
NAG C4   C  N S 346 
NAG C5   C  N R 347 
NAG C6   C  N N 348 
NAG C7   C  N N 349 
NAG C8   C  N N 350 
NAG N2   N  N N 351 
NAG O1   O  N N 352 
NAG O3   O  N N 353 
NAG O4   O  N N 354 
NAG O5   O  N N 355 
NAG O6   O  N N 356 
NAG O7   O  N N 357 
NAG H1   H  N N 358 
NAG H2   H  N N 359 
NAG H3   H  N N 360 
NAG H4   H  N N 361 
NAG H5   H  N N 362 
NAG H61  H  N N 363 
NAG H62  H  N N 364 
NAG H81  H  N N 365 
NAG H82  H  N N 366 
NAG H83  H  N N 367 
NAG HN2  H  N N 368 
NAG HO1  H  N N 369 
NAG HO3  H  N N 370 
NAG HO4  H  N N 371 
NAG HO6  H  N N 372 
PHE N    N  N N 373 
PHE CA   C  N S 374 
PHE C    C  N N 375 
PHE O    O  N N 376 
PHE CB   C  N N 377 
PHE CG   C  Y N 378 
PHE CD1  C  Y N 379 
PHE CD2  C  Y N 380 
PHE CE1  C  Y N 381 
PHE CE2  C  Y N 382 
PHE CZ   C  Y N 383 
PHE OXT  O  N N 384 
PHE H    H  N N 385 
PHE H2   H  N N 386 
PHE HA   H  N N 387 
PHE HB2  H  N N 388 
PHE HB3  H  N N 389 
PHE HD1  H  N N 390 
PHE HD2  H  N N 391 
PHE HE1  H  N N 392 
PHE HE2  H  N N 393 
PHE HZ   H  N N 394 
PHE HXT  H  N N 395 
PRO N    N  N N 396 
PRO CA   C  N S 397 
PRO C    C  N N 398 
PRO O    O  N N 399 
PRO CB   C  N N 400 
PRO CG   C  N N 401 
PRO CD   C  N N 402 
PRO OXT  O  N N 403 
PRO H    H  N N 404 
PRO HA   H  N N 405 
PRO HB2  H  N N 406 
PRO HB3  H  N N 407 
PRO HG2  H  N N 408 
PRO HG3  H  N N 409 
PRO HD2  H  N N 410 
PRO HD3  H  N N 411 
PRO HXT  H  N N 412 
SER N    N  N N 413 
SER CA   C  N S 414 
SER C    C  N N 415 
SER O    O  N N 416 
SER CB   C  N N 417 
SER OG   O  N N 418 
SER OXT  O  N N 419 
SER H    H  N N 420 
SER H2   H  N N 421 
SER HA   H  N N 422 
SER HB2  H  N N 423 
SER HB3  H  N N 424 
SER HG   H  N N 425 
SER HXT  H  N N 426 
THR N    N  N N 427 
THR CA   C  N S 428 
THR C    C  N N 429 
THR O    O  N N 430 
THR CB   C  N R 431 
THR OG1  O  N N 432 
THR CG2  C  N N 433 
THR OXT  O  N N 434 
THR H    H  N N 435 
THR H2   H  N N 436 
THR HA   H  N N 437 
THR HB   H  N N 438 
THR HG1  H  N N 439 
THR HG21 H  N N 440 
THR HG22 H  N N 441 
THR HG23 H  N N 442 
THR HXT  H  N N 443 
TRP N    N  N N 444 
TRP CA   C  N S 445 
TRP C    C  N N 446 
TRP O    O  N N 447 
TRP CB   C  N N 448 
TRP CG   C  Y N 449 
TRP CD1  C  Y N 450 
TRP CD2  C  Y N 451 
TRP NE1  N  Y N 452 
TRP CE2  C  Y N 453 
TRP CE3  C  Y N 454 
TRP CZ2  C  Y N 455 
TRP CZ3  C  Y N 456 
TRP CH2  C  Y N 457 
TRP OXT  O  N N 458 
TRP H    H  N N 459 
TRP H2   H  N N 460 
TRP HA   H  N N 461 
TRP HB2  H  N N 462 
TRP HB3  H  N N 463 
TRP HD1  H  N N 464 
TRP HE1  H  N N 465 
TRP HE3  H  N N 466 
TRP HZ2  H  N N 467 
TRP HZ3  H  N N 468 
TRP HH2  H  N N 469 
TRP HXT  H  N N 470 
TYR N    N  N N 471 
TYR CA   C  N S 472 
TYR C    C  N N 473 
TYR O    O  N N 474 
TYR CB   C  N N 475 
TYR CG   C  Y N 476 
TYR CD1  C  Y N 477 
TYR CD2  C  Y N 478 
TYR CE1  C  Y N 479 
TYR CE2  C  Y N 480 
TYR CZ   C  Y N 481 
TYR OH   O  N N 482 
TYR OXT  O  N N 483 
TYR H    H  N N 484 
TYR H2   H  N N 485 
TYR HA   H  N N 486 
TYR HB2  H  N N 487 
TYR HB3  H  N N 488 
TYR HD1  H  N N 489 
TYR HD2  H  N N 490 
TYR HE1  H  N N 491 
TYR HE2  H  N N 492 
TYR HH   H  N N 493 
TYR HXT  H  N N 494 
VAL N    N  N N 495 
VAL CA   C  N S 496 
VAL C    C  N N 497 
VAL O    O  N N 498 
VAL CB   C  N N 499 
VAL CG1  C  N N 500 
VAL CG2  C  N N 501 
VAL OXT  O  N N 502 
VAL H    H  N N 503 
VAL H2   H  N N 504 
VAL HA   H  N N 505 
VAL HB   H  N N 506 
VAL HG11 H  N N 507 
VAL HG12 H  N N 508 
VAL HG13 H  N N 509 
VAL HG21 H  N N 510 
VAL HG22 H  N N 511 
VAL HG23 H  N N 512 
VAL HXT  H  N N 513 
ZN  ZN   ZN N N 514 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
DCF N1  C2   doub Y N 107 
DCF N1  C9   sing Y N 108 
DCF C2  N3   sing Y N 109 
DCF C2  H2   sing N N 110 
DCF N3  C10  sing Y N 111 
DCF N3  C1S  sing N N 112 
DCF C9  C10  doub Y N 113 
DCF C9  C8   sing N N 114 
DCF C10 N4   sing N N 115 
DCF N4  C5   doub N N 116 
DCF C5  N6   sing N N 117 
DCF C5  H5   sing N N 118 
DCF N6  C7   sing N N 119 
DCF N6  HN6  sing N N 120 
DCF C7  C8   sing N N 121 
DCF C7  H71  sing N N 122 
DCF C7  H72  sing N N 123 
DCF C8  O8   sing N N 124 
DCF C8  H8   sing N N 125 
DCF O8  HO8  sing N N 126 
DCF C2S C3S  sing N N 127 
DCF C2S C1S  sing N N 128 
DCF C2S H2S1 sing N N 129 
DCF C2S H2S2 sing N N 130 
DCF C3S O3S  sing N N 131 
DCF C3S C4S  sing N N 132 
DCF C3S H3S  sing N N 133 
DCF O3S HO3  sing N N 134 
DCF O5S C5S  sing N N 135 
DCF O5S HO5  sing N N 136 
DCF C5S C4S  sing N N 137 
DCF C5S H5S1 sing N N 138 
DCF C5S H5S2 sing N N 139 
DCF C4S O4S  sing N N 140 
DCF C4S H4S  sing N N 141 
DCF O4S C1S  sing N N 142 
DCF C1S H1S  sing N N 143 
EDO C1  O1   sing N N 144 
EDO C1  C2   sing N N 145 
EDO C1  H11  sing N N 146 
EDO C1  H12  sing N N 147 
EDO O1  HO1  sing N N 148 
EDO C2  O2   sing N N 149 
EDO C2  H21  sing N N 150 
EDO C2  H22  sing N N 151 
EDO O2  HO2  sing N N 152 
GLN N   CA   sing N N 153 
GLN N   H    sing N N 154 
GLN N   H2   sing N N 155 
GLN CA  C    sing N N 156 
GLN CA  CB   sing N N 157 
GLN CA  HA   sing N N 158 
GLN C   O    doub N N 159 
GLN C   OXT  sing N N 160 
GLN CB  CG   sing N N 161 
GLN CB  HB2  sing N N 162 
GLN CB  HB3  sing N N 163 
GLN CG  CD   sing N N 164 
GLN CG  HG2  sing N N 165 
GLN CG  HG3  sing N N 166 
GLN CD  OE1  doub N N 167 
GLN CD  NE2  sing N N 168 
GLN NE2 HE21 sing N N 169 
GLN NE2 HE22 sing N N 170 
GLN OXT HXT  sing N N 171 
GLU N   CA   sing N N 172 
GLU N   H    sing N N 173 
GLU N   H2   sing N N 174 
GLU CA  C    sing N N 175 
GLU CA  CB   sing N N 176 
GLU CA  HA   sing N N 177 
GLU C   O    doub N N 178 
GLU C   OXT  sing N N 179 
GLU CB  CG   sing N N 180 
GLU CB  HB2  sing N N 181 
GLU CB  HB3  sing N N 182 
GLU CG  CD   sing N N 183 
GLU CG  HG2  sing N N 184 
GLU CG  HG3  sing N N 185 
GLU CD  OE1  doub N N 186 
GLU CD  OE2  sing N N 187 
GLU OE2 HE2  sing N N 188 
GLU OXT HXT  sing N N 189 
GLY N   CA   sing N N 190 
GLY N   H    sing N N 191 
GLY N   H2   sing N N 192 
GLY CA  C    sing N N 193 
GLY CA  HA2  sing N N 194 
GLY CA  HA3  sing N N 195 
GLY C   O    doub N N 196 
GLY C   OXT  sing N N 197 
GLY OXT HXT  sing N N 198 
HIS N   CA   sing N N 199 
HIS N   H    sing N N 200 
HIS N   H2   sing N N 201 
HIS CA  C    sing N N 202 
HIS CA  CB   sing N N 203 
HIS CA  HA   sing N N 204 
HIS C   O    doub N N 205 
HIS C   OXT  sing N N 206 
HIS CB  CG   sing N N 207 
HIS CB  HB2  sing N N 208 
HIS CB  HB3  sing N N 209 
HIS CG  ND1  sing Y N 210 
HIS CG  CD2  doub Y N 211 
HIS ND1 CE1  doub Y N 212 
HIS ND1 HD1  sing N N 213 
HIS CD2 NE2  sing Y N 214 
HIS CD2 HD2  sing N N 215 
HIS CE1 NE2  sing Y N 216 
HIS CE1 HE1  sing N N 217 
HIS NE2 HE2  sing N N 218 
HIS OXT HXT  sing N N 219 
HOH O   H1   sing N N 220 
HOH O   H2   sing N N 221 
ILE N   CA   sing N N 222 
ILE N   H    sing N N 223 
ILE N   H2   sing N N 224 
ILE CA  C    sing N N 225 
ILE CA  CB   sing N N 226 
ILE CA  HA   sing N N 227 
ILE C   O    doub N N 228 
ILE C   OXT  sing N N 229 
ILE CB  CG1  sing N N 230 
ILE CB  CG2  sing N N 231 
ILE CB  HB   sing N N 232 
ILE CG1 CD1  sing N N 233 
ILE CG1 HG12 sing N N 234 
ILE CG1 HG13 sing N N 235 
ILE CG2 HG21 sing N N 236 
ILE CG2 HG22 sing N N 237 
ILE CG2 HG23 sing N N 238 
ILE CD1 HD11 sing N N 239 
ILE CD1 HD12 sing N N 240 
ILE CD1 HD13 sing N N 241 
ILE OXT HXT  sing N N 242 
LEU N   CA   sing N N 243 
LEU N   H    sing N N 244 
LEU N   H2   sing N N 245 
LEU CA  C    sing N N 246 
LEU CA  CB   sing N N 247 
LEU CA  HA   sing N N 248 
LEU C   O    doub N N 249 
LEU C   OXT  sing N N 250 
LEU CB  CG   sing N N 251 
LEU CB  HB2  sing N N 252 
LEU CB  HB3  sing N N 253 
LEU CG  CD1  sing N N 254 
LEU CG  CD2  sing N N 255 
LEU CG  HG   sing N N 256 
LEU CD1 HD11 sing N N 257 
LEU CD1 HD12 sing N N 258 
LEU CD1 HD13 sing N N 259 
LEU CD2 HD21 sing N N 260 
LEU CD2 HD22 sing N N 261 
LEU CD2 HD23 sing N N 262 
LEU OXT HXT  sing N N 263 
LYS N   CA   sing N N 264 
LYS N   H    sing N N 265 
LYS N   H2   sing N N 266 
LYS CA  C    sing N N 267 
LYS CA  CB   sing N N 268 
LYS CA  HA   sing N N 269 
LYS C   O    doub N N 270 
LYS C   OXT  sing N N 271 
LYS CB  CG   sing N N 272 
LYS CB  HB2  sing N N 273 
LYS CB  HB3  sing N N 274 
LYS CG  CD   sing N N 275 
LYS CG  HG2  sing N N 276 
LYS CG  HG3  sing N N 277 
LYS CD  CE   sing N N 278 
LYS CD  HD2  sing N N 279 
LYS CD  HD3  sing N N 280 
LYS CE  NZ   sing N N 281 
LYS CE  HE2  sing N N 282 
LYS CE  HE3  sing N N 283 
LYS NZ  HZ1  sing N N 284 
LYS NZ  HZ2  sing N N 285 
LYS NZ  HZ3  sing N N 286 
LYS OXT HXT  sing N N 287 
MAN C1  C2   sing N N 288 
MAN C1  O1   sing N N 289 
MAN C1  O5   sing N N 290 
MAN C1  H1   sing N N 291 
MAN C2  C3   sing N N 292 
MAN C2  O2   sing N N 293 
MAN C2  H2   sing N N 294 
MAN C3  C4   sing N N 295 
MAN C3  O3   sing N N 296 
MAN C3  H3   sing N N 297 
MAN C4  C5   sing N N 298 
MAN C4  O4   sing N N 299 
MAN C4  H4   sing N N 300 
MAN C5  C6   sing N N 301 
MAN C5  O5   sing N N 302 
MAN C5  H5   sing N N 303 
MAN C6  O6   sing N N 304 
MAN C6  H61  sing N N 305 
MAN C6  H62  sing N N 306 
MAN O1  HO1  sing N N 307 
MAN O2  HO2  sing N N 308 
MAN O3  HO3  sing N N 309 
MAN O4  HO4  sing N N 310 
MAN O6  HO6  sing N N 311 
MET N   CA   sing N N 312 
MET N   H    sing N N 313 
MET N   H2   sing N N 314 
MET CA  C    sing N N 315 
MET CA  CB   sing N N 316 
MET CA  HA   sing N N 317 
MET C   O    doub N N 318 
MET C   OXT  sing N N 319 
MET CB  CG   sing N N 320 
MET CB  HB2  sing N N 321 
MET CB  HB3  sing N N 322 
MET CG  SD   sing N N 323 
MET CG  HG2  sing N N 324 
MET CG  HG3  sing N N 325 
MET SD  CE   sing N N 326 
MET CE  HE1  sing N N 327 
MET CE  HE2  sing N N 328 
MET CE  HE3  sing N N 329 
MET OXT HXT  sing N N 330 
NAG C1  C2   sing N N 331 
NAG C1  O1   sing N N 332 
NAG C1  O5   sing N N 333 
NAG C1  H1   sing N N 334 
NAG C2  C3   sing N N 335 
NAG C2  N2   sing N N 336 
NAG C2  H2   sing N N 337 
NAG C3  C4   sing N N 338 
NAG C3  O3   sing N N 339 
NAG C3  H3   sing N N 340 
NAG C4  C5   sing N N 341 
NAG C4  O4   sing N N 342 
NAG C4  H4   sing N N 343 
NAG C5  C6   sing N N 344 
NAG C5  O5   sing N N 345 
NAG C5  H5   sing N N 346 
NAG C6  O6   sing N N 347 
NAG C6  H61  sing N N 348 
NAG C6  H62  sing N N 349 
NAG C7  C8   sing N N 350 
NAG C7  N2   sing N N 351 
NAG C7  O7   doub N N 352 
NAG C8  H81  sing N N 353 
NAG C8  H82  sing N N 354 
NAG C8  H83  sing N N 355 
NAG N2  HN2  sing N N 356 
NAG O1  HO1  sing N N 357 
NAG O3  HO3  sing N N 358 
NAG O4  HO4  sing N N 359 
NAG O6  HO6  sing N N 360 
PHE N   CA   sing N N 361 
PHE N   H    sing N N 362 
PHE N   H2   sing N N 363 
PHE CA  C    sing N N 364 
PHE CA  CB   sing N N 365 
PHE CA  HA   sing N N 366 
PHE C   O    doub N N 367 
PHE C   OXT  sing N N 368 
PHE CB  CG   sing N N 369 
PHE CB  HB2  sing N N 370 
PHE CB  HB3  sing N N 371 
PHE CG  CD1  doub Y N 372 
PHE CG  CD2  sing Y N 373 
PHE CD1 CE1  sing Y N 374 
PHE CD1 HD1  sing N N 375 
PHE CD2 CE2  doub Y N 376 
PHE CD2 HD2  sing N N 377 
PHE CE1 CZ   doub Y N 378 
PHE CE1 HE1  sing N N 379 
PHE CE2 CZ   sing Y N 380 
PHE CE2 HE2  sing N N 381 
PHE CZ  HZ   sing N N 382 
PHE OXT HXT  sing N N 383 
PRO N   CA   sing N N 384 
PRO N   CD   sing N N 385 
PRO N   H    sing N N 386 
PRO CA  C    sing N N 387 
PRO CA  CB   sing N N 388 
PRO CA  HA   sing N N 389 
PRO C   O    doub N N 390 
PRO C   OXT  sing N N 391 
PRO CB  CG   sing N N 392 
PRO CB  HB2  sing N N 393 
PRO CB  HB3  sing N N 394 
PRO CG  CD   sing N N 395 
PRO CG  HG2  sing N N 396 
PRO CG  HG3  sing N N 397 
PRO CD  HD2  sing N N 398 
PRO CD  HD3  sing N N 399 
PRO OXT HXT  sing N N 400 
SER N   CA   sing N N 401 
SER N   H    sing N N 402 
SER N   H2   sing N N 403 
SER CA  C    sing N N 404 
SER CA  CB   sing N N 405 
SER CA  HA   sing N N 406 
SER C   O    doub N N 407 
SER C   OXT  sing N N 408 
SER CB  OG   sing N N 409 
SER CB  HB2  sing N N 410 
SER CB  HB3  sing N N 411 
SER OG  HG   sing N N 412 
SER OXT HXT  sing N N 413 
THR N   CA   sing N N 414 
THR N   H    sing N N 415 
THR N   H2   sing N N 416 
THR CA  C    sing N N 417 
THR CA  CB   sing N N 418 
THR CA  HA   sing N N 419 
THR C   O    doub N N 420 
THR C   OXT  sing N N 421 
THR CB  OG1  sing N N 422 
THR CB  CG2  sing N N 423 
THR CB  HB   sing N N 424 
THR OG1 HG1  sing N N 425 
THR CG2 HG21 sing N N 426 
THR CG2 HG22 sing N N 427 
THR CG2 HG23 sing N N 428 
THR OXT HXT  sing N N 429 
TRP N   CA   sing N N 430 
TRP N   H    sing N N 431 
TRP N   H2   sing N N 432 
TRP CA  C    sing N N 433 
TRP CA  CB   sing N N 434 
TRP CA  HA   sing N N 435 
TRP C   O    doub N N 436 
TRP C   OXT  sing N N 437 
TRP CB  CG   sing N N 438 
TRP CB  HB2  sing N N 439 
TRP CB  HB3  sing N N 440 
TRP CG  CD1  doub Y N 441 
TRP CG  CD2  sing Y N 442 
TRP CD1 NE1  sing Y N 443 
TRP CD1 HD1  sing N N 444 
TRP CD2 CE2  doub Y N 445 
TRP CD2 CE3  sing Y N 446 
TRP NE1 CE2  sing Y N 447 
TRP NE1 HE1  sing N N 448 
TRP CE2 CZ2  sing Y N 449 
TRP CE3 CZ3  doub Y N 450 
TRP CE3 HE3  sing N N 451 
TRP CZ2 CH2  doub Y N 452 
TRP CZ2 HZ2  sing N N 453 
TRP CZ3 CH2  sing Y N 454 
TRP CZ3 HZ3  sing N N 455 
TRP CH2 HH2  sing N N 456 
TRP OXT HXT  sing N N 457 
TYR N   CA   sing N N 458 
TYR N   H    sing N N 459 
TYR N   H2   sing N N 460 
TYR CA  C    sing N N 461 
TYR CA  CB   sing N N 462 
TYR CA  HA   sing N N 463 
TYR C   O    doub N N 464 
TYR C   OXT  sing N N 465 
TYR CB  CG   sing N N 466 
TYR CB  HB2  sing N N 467 
TYR CB  HB3  sing N N 468 
TYR CG  CD1  doub Y N 469 
TYR CG  CD2  sing Y N 470 
TYR CD1 CE1  sing Y N 471 
TYR CD1 HD1  sing N N 472 
TYR CD2 CE2  doub Y N 473 
TYR CD2 HD2  sing N N 474 
TYR CE1 CZ   doub Y N 475 
TYR CE1 HE1  sing N N 476 
TYR CE2 CZ   sing Y N 477 
TYR CE2 HE2  sing N N 478 
TYR CZ  OH   sing N N 479 
TYR OH  HH   sing N N 480 
TYR OXT HXT  sing N N 481 
VAL N   CA   sing N N 482 
VAL N   H    sing N N 483 
VAL N   H2   sing N N 484 
VAL CA  C    sing N N 485 
VAL CA  CB   sing N N 486 
VAL CA  HA   sing N N 487 
VAL C   O    doub N N 488 
VAL C   OXT  sing N N 489 
VAL CB  CG1  sing N N 490 
VAL CB  CG2  sing N N 491 
VAL CB  HB   sing N N 492 
VAL CG1 HG11 sing N N 493 
VAL CG1 HG12 sing N N 494 
VAL CG1 HG13 sing N N 495 
VAL CG2 HG21 sing N N 496 
VAL CG2 HG22 sing N N 497 
VAL CG2 HG23 sing N N 498 
VAL OXT HXT  sing N N 499 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM134744 1 
'Cancer Prevention and Research Institute of Texas (CPRIT)'                                'United States' RR160029    2 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
2 MAN 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NTJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014848 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009123 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005829 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 6.96715  ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 29.81721 ?       ? ? 5.87945  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . LEU A 1 28  ? 64.90434  -32.46348 -42.67481 1.000 48.73681  ?  28  LEU A N   1 
ATOM   2    C  CA  . LEU A 1 28  ? 65.42959  -33.19580 -43.82267 1.000 61.85582  ?  28  LEU A CA  1 
ATOM   3    C  C   . LEU A 1 28  ? 64.98908  -32.57378 -45.14187 1.000 64.83487  ?  28  LEU A C   1 
ATOM   4    O  O   . LEU A 1 28  ? 65.71840  -31.78103 -45.74018 1.000 66.84355  ?  28  LEU A O   1 
ATOM   5    C  CB  . LEU A 1 28  ? 64.99094  -34.66085 -43.77459 1.000 38.88975  ?  28  LEU A CB  1 
ATOM   6    C  CG  . LEU A 1 28  ? 66.03276  -35.66628 -43.28409 1.000 41.67585  ?  28  LEU A CG  1 
ATOM   7    C  CD1 . LEU A 1 28  ? 65.54242  -37.08740 -43.50934 1.000 41.39835  ?  28  LEU A CD1 1 
ATOM   8    C  CD2 . LEU A 1 28  ? 67.37037  -35.43717 -43.97579 1.000 36.26306  ?  28  LEU A CD2 1 
ATOM   9    N  N   . THR A 1 29  ? 63.79170  -32.94938 -45.58750 1.000 53.67967  ?  29  THR A N   1 
ATOM   10   C  CA  . THR A 1 29  ? 63.26277  -32.44604 -46.84724 1.000 60.80697  ?  29  THR A CA  1 
ATOM   11   C  C   . THR A 1 29  ? 63.16314  -30.92675 -46.80793 1.000 60.56865  ?  29  THR A C   1 
ATOM   12   O  O   . THR A 1 29  ? 62.84865  -30.33743 -45.77090 1.000 62.53517  ?  29  THR A O   1 
ATOM   13   C  CB  . THR A 1 29  ? 61.88517  -33.05719 -47.12349 1.000 49.43899  ?  29  THR A CB  1 
ATOM   14   O  OG1 . THR A 1 29  ? 61.95572  -34.48192 -46.98863 1.000 56.38789  ?  29  THR A OG1 1 
ATOM   15   C  CG2 . THR A 1 29  ? 61.41221  -32.71521 -48.52997 1.000 47.58086  ?  29  THR A CG2 1 
ATOM   16   N  N   . SER A 1 30  ? 63.46682  -30.28817 -47.94237 1.000 62.14759  ?  30  SER A N   1 
ATOM   17   C  CA  . SER A 1 30  ? 63.26251  -28.84739 -48.04726 1.000 57.00596  ?  30  SER A CA  1 
ATOM   18   C  C   . SER A 1 30  ? 61.81532  -28.47692 -47.75534 1.000 48.58008  ?  30  SER A C   1 
ATOM   19   O  O   . SER A 1 30  ? 61.54784  -27.41445 -47.18227 1.000 40.10142  ?  30  SER A O   1 
ATOM   20   C  CB  . SER A 1 30  ? 63.67078  -28.35533 -49.43615 1.000 44.50896  ?  30  SER A CB  1 
ATOM   21   O  OG  . SER A 1 30  ? 65.03882  -28.62147 -49.68989 1.000 43.32811  ?  30  SER A OG  1 
ATOM   22   N  N   . LYS A 1 31  ? 60.87392  -29.34638 -48.13064 1.000 42.21701  ?  31  LYS A N   1 
ATOM   23   C  CA  . LYS A 1 31  ? 59.48001  -29.15185 -47.74849 1.000 40.99518  ?  31  LYS A CA  1 
ATOM   24   C  C   . LYS A 1 31  ? 59.31828  -29.17554 -46.23301 1.000 43.84248  ?  31  LYS A C   1 
ATOM   25   O  O   . LYS A 1 31  ? 58.59516  -28.34942 -45.66570 1.000 39.01570  ?  31  LYS A O   1 
ATOM   26   C  CB  . LYS A 1 31  ? 58.61336  -30.22697 -48.40593 1.000 37.67662  ?  31  LYS A CB  1 
ATOM   27   C  CG  . LYS A 1 31  ? 57.13064  -30.15402 -48.08087 1.000 24.50917  ?  31  LYS A CG  1 
ATOM   28   C  CD  . LYS A 1 31  ? 56.37144  -31.23311 -48.83985 1.000 18.46425  ?  31  LYS A CD  1 
ATOM   29   C  CE  . LYS A 1 31  ? 54.89068  -31.22547 -48.50715 1.000 21.19641  ?  31  LYS A CE  1 
ATOM   30   N  NZ  . LYS A 1 31  ? 54.15806  -32.28162 -49.26213 1.000 20.40812  ?  31  LYS A NZ  1 
ATOM   31   N  N   . ALA A 1 32  ? 59.99172  -30.11261 -45.55930 1.000 48.11935  ?  32  ALA A N   1 
ATOM   32   C  CA  . ALA A 1 32  ? 59.90571  -30.19215 -44.10339 1.000 38.03304  ?  32  ALA A CA  1 
ATOM   33   C  C   . ALA A 1 32  ? 60.51726  -28.96467 -43.43544 1.000 39.78368  ?  32  ALA A C   1 
ATOM   34   O  O   . ALA A 1 32  ? 59.96720  -28.44770 -42.45656 1.000 45.13853  ?  32  ALA A O   1 
ATOM   35   C  CB  . ALA A 1 32  ? 60.58381  -31.46828 -43.60736 1.000 36.55891  ?  32  ALA A CB  1 
ATOM   36   N  N   . ALA A 1 33  ? 61.66120  -28.49162 -43.93720 1.000 37.71377  ?  33  ALA A N   1 
ATOM   37   C  CA  . ALA A 1 33  ? 62.26026  -27.27805 -43.38858 1.000 36.02688  ?  33  ALA A CA  1 
ATOM   38   C  C   . ALA A 1 33  ? 61.35414  -26.07401 -43.60865 1.000 36.55046  ?  33  ALA A C   1 
ATOM   39   O  O   . ALA A 1 33  ? 61.20020  -25.22540 -42.71822 1.000 35.63025  ?  33  ALA A O   1 
ATOM   40   C  CB  . ALA A 1 33  ? 63.63399  -27.04012 -44.01463 1.000 36.43591  ?  33  ALA A CB  1 
ATOM   41   N  N   . TYR A 1 34  ? 60.74305  -25.98718 -44.79272 1.000 36.36215  ?  34  TYR A N   1 
ATOM   42   C  CA  . TYR A 1 34  ? 59.78531  -24.92185 -45.05873 1.000 31.89441  ?  34  TYR A CA  1 
ATOM   43   C  C   . TYR A 1 34  ? 58.61358  -24.98849 -44.09003 1.000 33.73726  ?  34  TYR A C   1 
ATOM   44   O  O   . TYR A 1 34  ? 58.14816  -23.95607 -43.60081 1.000 31.92540  ?  34  TYR A O   1 
ATOM   45   C  CB  . TYR A 1 34  ? 59.29355  -25.00977 -46.50482 1.000 30.84792  ?  34  TYR A CB  1 
ATOM   46   C  CG  . TYR A 1 34  ? 58.23342  -23.99127 -46.86269 1.000 25.11154  ?  34  TYR A CG  1 
ATOM   47   C  CD1 . TYR A 1 34  ? 56.88503  -24.25058 -46.63894 1.000 27.36034  ?  34  TYR A CD1 1 
ATOM   48   C  CD2 . TYR A 1 34  ? 58.57931  -22.77433 -47.43143 1.000 22.65294  ?  34  TYR A CD2 1 
ATOM   49   C  CE1 . TYR A 1 34  ? 55.91687  -23.32237 -46.95877 1.000 24.39018  ?  34  TYR A CE1 1 
ATOM   50   C  CE2 . TYR A 1 34  ? 57.61598  -21.84240 -47.76046 1.000 26.24418  ?  34  TYR A CE2 1 
ATOM   51   C  CZ  . TYR A 1 34  ? 56.28778  -22.12174 -47.52190 1.000 21.47733  ?  34  TYR A CZ  1 
ATOM   52   O  OH  . TYR A 1 34  ? 55.32744  -21.19573 -47.84770 1.000 18.26725  ?  34  TYR A OH  1 
ATOM   53   N  N   . LEU A 1 35  ? 58.11664  -26.19543 -43.80965 1.000 28.36095  ?  35  LEU A N   1 
ATOM   54   C  CA  . LEU A 1 35  ? 56.99694  -26.34013 -42.88341 1.000 26.94161  ?  35  LEU A CA  1 
ATOM   55   C  C   . LEU A 1 35  ? 57.39485  -25.95799 -41.46309 1.000 31.91862  ?  35  LEU A C   1 
ATOM   56   O  O   . LEU A 1 35  ? 56.59837  -25.36303 -40.72840 1.000 28.70878  ?  35  LEU A O   1 
ATOM   57   C  CB  . LEU A 1 35  ? 56.46014  -27.76919 -42.92433 1.000 18.31533  ?  35  LEU A CB  1 
ATOM   58   C  CG  . LEU A 1 35  ? 55.76997  -28.17481 -44.22544 1.000 19.83148  ?  35  LEU A CG  1 
ATOM   59   C  CD1 . LEU A 1 35  ? 55.11593  -29.53885 -44.08216 1.000 26.30733  ?  35  LEU A CD1 1 
ATOM   60   C  CD2 . LEU A 1 35  ? 54.75368  -27.12386 -44.63987 1.000 23.98932  ?  35  LEU A CD2 1 
ATOM   61   N  N   . LEU A 1 36  ? 58.61489  -26.30759 -41.05228 1.000 34.06298  ?  36  LEU A N   1 
ATOM   62   C  CA  . LEU A 1 36  ? 59.09262  -25.89906 -39.73452 1.000 35.35488  ?  36  LEU A CA  1 
ATOM   63   C  C   . LEU A 1 36  ? 59.16762  -24.38114 -39.62951 1.000 37.73880  ?  36  LEU A C   1 
ATOM   64   O  O   . LEU A 1 36  ? 58.72686  -23.79332 -38.63174 1.000 42.07898  ?  36  LEU A O   1 
ATOM   65   C  CB  . LEU A 1 36  ? 60.45800  -26.52792 -39.45189 1.000 32.81610  ?  36  LEU A CB  1 
ATOM   66   C  CG  . LEU A 1 36  ? 60.49939  -27.87370 -38.72078 1.000 39.48051  ?  36  LEU A CG  1 
ATOM   67   C  CD1 . LEU A 1 36  ? 59.50612  -28.87008 -39.30634 1.000 33.82735  ?  36  LEU A CD1 1 
ATOM   68   C  CD2 . LEU A 1 36  ? 61.91012  -28.44412 -38.75348 1.000 32.40939  ?  36  LEU A CD2 1 
ATOM   69   N  N   . LYS A 1 37  ? 59.70480  -23.72797 -40.66289 1.000 31.28769  ?  37  LYS A N   1 
ATOM   70   C  CA  . LYS A 1 37  ? 59.76618  -22.26955 -40.66346 1.000 26.85912  ?  37  LYS A CA  1 
ATOM   71   C  C   . LYS A 1 37  ? 58.36688  -21.65964 -40.69308 1.000 27.48760  ?  37  LYS A C   1 
ATOM   72   O  O   . LYS A 1 37  ? 58.12015  -20.62105 -40.06641 1.000 22.89880  ?  37  LYS A O   1 
ATOM   73   C  CB  . LYS A 1 37  ? 60.60351  -21.78950 -41.84874 1.000 24.65314  ?  37  LYS A CB  1 
ATOM   74   C  CG  . LYS A 1 37  ? 61.42580  -20.54244 -41.56911 1.000 34.66226  ?  37  LYS A CG  1 
ATOM   75   C  CD  . LYS A 1 37  ? 62.58783  -20.41730 -42.54471 1.000 33.79010  ?  37  LYS A CD  1 
ATOM   76   C  CE  . LYS A 1 37  ? 63.57500  -21.56415 -42.37790 1.000 32.45564  ?  37  LYS A CE  1 
ATOM   77   N  NZ  . LYS A 1 37  ? 64.75180  -21.42864 -43.28212 1.000 37.34334  ?  37  LYS A NZ  1 
ATOM   78   N  N   . ARG A 1 38  ? 57.43962  -22.29576 -41.41457 1.000 28.22399  ?  38  ARG A N   1 
ATOM   79   C  CA  . ARG A 1 38  ? 56.05846  -21.82643 -41.45500 1.000 30.11993  ?  38  ARG A CA  1 
ATOM   80   C  C   . ARG A 1 38  ? 55.40867  -21.90368 -40.08404 1.000 34.72961  ?  38  ARG A C   1 
ATOM   81   O  O   . ARG A 1 38  ? 54.70908  -20.97441 -39.66926 1.000 33.33034  ?  38  ARG A O   1 
ATOM   82   C  CB  . ARG A 1 38  ? 55.25505  -22.64405 -42.46778 1.000 27.84548  ?  38  ARG A CB  1 
ATOM   83   C  CG  . ARG A 1 38  ? 53.79077  -22.23499 -42.58328 1.000 22.33746  ?  38  ARG A CG  1 
ATOM   84   C  CD  . ARG A 1 38  ? 53.00571  -23.22188 -43.43714 1.000 22.81753  ?  38  ARG A CD  1 
ATOM   85   N  NE  . ARG A 1 38  ? 51.71111  -22.69163 -43.85114 1.000 23.12654  ?  38  ARG A NE  1 
ATOM   86   C  CZ  . ARG A 1 38  ? 50.56267  -22.92911 -43.23129 1.000 25.69990  ?  38  ARG A CZ  1 
ATOM   87   N  NH1 . ARG A 1 38  ? 50.50385  -23.68923 -42.15017 1.000 30.56404  ?  38  ARG A NH1 1 
ATOM   88   N  NH2 . ARG A 1 38  ? 49.44422  -22.38988 -43.70881 1.000 20.06834  ?  38  ARG A NH2 1 
ATOM   89   N  N   . ASN A 1 39  ? 55.61111  -23.01539 -39.37549 1.000 40.65675  ?  39  ASN A N   1 
ATOM   90   C  CA  . ASN A 1 39  ? 55.07646  -23.13293 -38.02464 1.000 38.79041  ?  39  ASN A CA  1 
ATOM   91   C  C   . ASN A 1 39  ? 55.69266  -22.08882 -37.10660 1.000 36.81967  ?  39  ASN A C   1 
ATOM   92   O  O   . ASN A 1 39  ? 54.98866  -21.47338 -36.29766 1.000 40.35544  ?  39  ASN A O   1 
ATOM   93   C  CB  . ASN A 1 39  ? 55.31038  -24.54236 -37.48295 1.000 39.09232  ?  39  ASN A CB  1 
ATOM   94   C  CG  . ASN A 1 39  ? 54.27115  -25.53140 -37.97277 1.000 42.77308  ?  39  ASN A CG  1 
ATOM   95   O  OD1 . ASN A 1 39  ? 53.08590  -25.20910 -38.06198 1.000 43.00021  ?  39  ASN A OD1 1 
ATOM   96   N  ND2 . ASN A 1 39  ? 54.71056  -26.74155 -38.29740 1.000 38.94599  ?  39  ASN A ND2 1 
ATOM   97   N  N   . SER A 1 40  ? 57.00289  -21.85920 -37.23434 1.000 30.70486  ?  40  SER A N   1 
ATOM   98   C  CA  . SER A 1 40  ? 57.64927  -20.81248 -36.44822 1.000 27.30978  ?  40  SER A CA  1 
ATOM   99   C  C   . SER A 1 40  ? 56.98451  -19.46179 -36.68535 1.000 28.85650  ?  40  SER A C   1 
ATOM   100  O  O   . SER A 1 40  ? 56.58779  -18.77686 -35.73587 1.000 28.07459  ?  40  SER A O   1 
ATOM   101  C  CB  . SER A 1 40  ? 59.13901  -20.74210 -36.78861 1.000 35.00201  ?  40  SER A CB  1 
ATOM   102  O  OG  . SER A 1 40  ? 59.79840  -21.95619 -36.47665 1.000 52.60871  ?  40  SER A OG  1 
ATOM   103  N  N   . LEU A 1 41  ? 56.83096  -19.07672 -37.95522 1.000 33.02816  ?  41  LEU A N   1 
ATOM   104  C  CA  . LEU A 1 41  ? 56.26962  -17.76688 -38.27947 1.000 29.64492  ?  41  LEU A CA  1 
ATOM   105  C  C   . LEU A 1 41  ? 54.81311  -17.64783 -37.83956 1.000 28.92563  ?  41  LEU A C   1 
ATOM   106  O  O   . LEU A 1 41  ? 54.40765  -16.61684 -37.28680 1.000 29.79768  ?  41  LEU A O   1 
ATOM   107  C  CB  . LEU A 1 41  ? 56.39866  -17.50228 -39.77901 1.000 22.91635  ?  41  LEU A CB  1 
ATOM   108  C  CG  . LEU A 1 41  ? 55.71938  -16.23628 -40.30110 1.000 19.61890  ?  41  LEU A CG  1 
ATOM   109  C  CD1 . LEU A 1 41  ? 56.28649  -14.99989 -39.62150 1.000 20.74808  ?  41  LEU A CD1 1 
ATOM   110  C  CD2 . LEU A 1 41  ? 55.85718  -16.13842 -41.81273 1.000 22.85756  ?  41  LEU A CD2 1 
ATOM   111  N  N   . ILE A 1 42  ? 54.01042  -18.68871 -38.07141 1.000 26.05037  ?  42  ILE A N   1 
ATOM   112  C  CA  . ILE A 1 42  ? 52.58846  -18.60872 -37.75531 1.000 24.45662  ?  42  ILE A CA  1 
ATOM   113  C  C   . ILE A 1 42  ? 52.37186  -18.58655 -36.24818 1.000 29.91892  ?  42  ILE A C   1 
ATOM   114  O  O   . ILE A 1 42  ? 51.51936  -17.84553 -35.74743 1.000 31.80345  ?  42  ILE A O   1 
ATOM   115  C  CB  . ILE A 1 42  ? 51.82106  -19.75993 -38.42992 1.000 23.33746  ?  42  ILE A CB  1 
ATOM   116  C  CG1 . ILE A 1 42  ? 51.86766  -19.60084 -39.95012 1.000 26.38038  ?  42  ILE A CG1 1 
ATOM   117  C  CG2 . ILE A 1 42  ? 50.37698  -19.79757 -37.95352 1.000 14.14666  ?  42  ILE A CG2 1 
ATOM   118  C  CD1 . ILE A 1 42  ? 51.04159  -20.61966 -40.69606 1.000 31.58758  ?  42  ILE A CD1 1 
ATOM   119  N  N   . GLU A 1 43  ? 53.13041  -19.39240 -35.49780 1.000 31.41421  ?  43  GLU A N   1 
ATOM   120  C  CA  . GLU A 1 43  ? 53.04503  -19.33187 -34.04265 1.000 34.69257  ?  43  GLU A CA  1 
ATOM   121  C  C   . GLU A 1 43  ? 53.51454  -17.97772 -33.52597 1.000 33.45137  ?  43  GLU A C   1 
ATOM   122  O  O   . GLU A 1 43  ? 52.90692  -17.40754 -32.61124 1.000 32.56515  ?  43  GLU A O   1 
ATOM   123  C  CB  . GLU A 1 43  ? 53.86792  -20.46249 -33.42406 1.000 38.31071  ?  43  GLU A CB  1 
ATOM   124  C  CG  . GLU A 1 43  ? 53.25350  -21.08356 -32.17757 1.000 59.68865  ?  43  GLU A CG  1 
ATOM   125  C  CD  . GLU A 1 43  ? 52.16944  -22.10139 -32.49658 1.000 103.49164 ?  43  GLU A CD  1 
ATOM   126  O  OE1 . GLU A 1 43  ? 51.78319  -22.22156 -33.67912 1.000 95.26190  ?  43  GLU A OE1 1 
ATOM   127  O  OE2 . GLU A 1 43  ? 51.70699  -22.78874 -31.56143 1.000 129.87805 -1 43  GLU A OE2 1 
ATOM   128  N  N   . GLU A 1 44  ? 54.58615  -17.43996 -34.11687 1.000 32.62831  ?  44  GLU A N   1 
ATOM   129  C  CA  . GLU A 1 44  ? 55.08442  -16.12469 -33.73314 1.000 31.19253  ?  44  GLU A CA  1 
ATOM   130  C  C   . GLU A 1 44  ? 54.01801  -15.05464 -33.93117 1.000 35.41508  ?  44  GLU A C   1 
ATOM   131  O  O   . GLU A 1 44  ? 53.86380  -14.15530 -33.09617 1.000 33.99191  ?  44  GLU A O   1 
ATOM   132  C  CB  . GLU A 1 44  ? 56.33541  -15.80891 -34.55492 1.000 31.68081  ?  44  GLU A CB  1 
ATOM   133  C  CG  . GLU A 1 44  ? 57.27988  -14.78167 -33.96505 1.000 42.92738  ?  44  GLU A CG  1 
ATOM   134  C  CD  . GLU A 1 44  ? 58.58048  -14.69468 -34.74770 1.000 56.08422  ?  44  GLU A CD  1 
ATOM   135  O  OE1 . GLU A 1 44  ? 58.80072  -15.55127 -35.63182 1.000 39.41566  ?  44  GLU A OE1 1 
ATOM   136  O  OE2 . GLU A 1 44  ? 59.38071  -13.77313 -34.48293 1.000 64.25235  -1 44  GLU A OE2 1 
ATOM   137  N  N   . ASP A 1 45  ? 53.26951  -15.13965 -35.03294 1.000 35.42365  ?  45  ASP A N   1 
ATOM   138  C  CA  . ASP A 1 45  ? 52.22590  -14.15345 -35.29876 1.000 31.18847  ?  45  ASP A CA  1 
ATOM   139  C  C   . ASP A 1 45  ? 51.00938  -14.35952 -34.40092 1.000 27.30127  ?  45  ASP A C   1 
ATOM   140  O  O   . ASP A 1 45  ? 50.45380  -13.39057 -33.87015 1.000 25.00948  ?  45  ASP A O   1 
ATOM   141  C  CB  . ASP A 1 45  ? 51.82616  -14.20686 -36.77380 1.000 29.69156  ?  45  ASP A CB  1 
ATOM   142  C  CG  . ASP A 1 45  ? 50.63356  -13.32600 -37.09090 1.000 20.61741  ?  45  ASP A CG  1 
ATOM   143  O  OD1 . ASP A 1 45  ? 49.48819  -13.75150 -36.83229 1.000 19.80585  ?  45  ASP A OD1 1 
ATOM   144  O  OD2 . ASP A 1 45  ? 50.84388  -12.20252 -37.59212 1.000 20.25630  -1 45  ASP A OD2 1 
ATOM   145  N  N   . ALA A 1 46  ? 50.57970  -15.60841 -34.21682 1.000 26.56104  ?  46  ALA A N   1 
ATOM   146  C  CA  . ALA A 1 46  ? 49.34765  -15.89394 -33.49382 1.000 26.69403  ?  46  ALA A CA  1 
ATOM   147  C  C   . ALA A 1 46  ? 49.51317  -15.85934 -31.98111 1.000 31.35515  ?  46  ALA A C   1 
ATOM   148  O  O   . ALA A 1 46  ? 48.50453  -15.87268 -31.26727 1.000 27.63609  ?  46  ALA A O   1 
ATOM   149  C  CB  . ALA A 1 46  ? 48.79626  -17.25761 -33.91570 1.000 24.72052  ?  46  ALA A CB  1 
ATOM   150  N  N   . SER A 1 47  ? 50.74498  -15.81608 -31.47330 1.000 35.27419  ?  47  SER A N   1 
ATOM   151  C  CA  . SER A 1 47  ? 50.95356  -15.69151 -30.03775 1.000 33.57547  ?  47  SER A CA  1 
ATOM   152  C  C   . SER A 1 47  ? 50.79370  -14.26336 -29.53714 1.000 37.03267  ?  47  SER A C   1 
ATOM   153  O  O   . SER A 1 47  ? 50.86088  -14.03936 -28.32397 1.000 38.83415  ?  47  SER A O   1 
ATOM   154  C  CB  . SER A 1 47  ? 52.34568  -16.20314 -29.66542 1.000 30.23816  ?  47  SER A CB  1 
ATOM   155  O  OG  . SER A 1 47  ? 53.35139  -15.39216 -30.24817 1.000 26.99418  ?  47  SER A OG  1 
ATOM   156  N  N   . ARG A 1 48  ? 50.59924  -13.29901 -30.43189 1.000 36.32706  ?  48  ARG A N   1 
ATOM   157  C  CA  . ARG A 1 48  ? 50.49271  -11.89662 -30.05712 1.000 30.42255  ?  48  ARG A CA  1 
ATOM   158  C  C   . ARG A 1 48  ? 49.05791  -11.44657 -29.82234 1.000 28.36528  ?  48  ARG A C   1 
ATOM   159  O  O   . ARG A 1 48  ? 48.84456  -10.29591 -29.42841 1.000 29.75230  ?  48  ARG A O   1 
ATOM   160  C  CB  . ARG A 1 48  ? 51.13903  -11.02178 -31.13355 1.000 29.62699  ?  48  ARG A CB  1 
ATOM   161  C  CG  . ARG A 1 48  ? 52.55775  -11.44172 -31.46918 1.000 37.75622  ?  48  ARG A CG  1 
ATOM   162  C  CD  . ARG A 1 48  ? 53.17580  -10.54404 -32.52004 1.000 35.11535  ?  48  ARG A CD  1 
ATOM   163  N  NE  . ARG A 1 48  ? 53.15057  -9.14310  -32.12046 1.000 29.83447  ?  48  ARG A NE  1 
ATOM   164  C  CZ  . ARG A 1 48  ? 53.96887  -8.21783  -32.60032 1.000 32.01349  ?  48  ARG A CZ  1 
ATOM   165  N  NH1 . ARG A 1 48  ? 54.90921  -8.51830  -33.48015 1.000 35.25982  ?  48  ARG A NH1 1 
ATOM   166  N  NH2 . ARG A 1 48  ? 53.84667  -6.96209  -32.18027 1.000 32.23384  ?  48  ARG A NH2 1 
ATOM   167  N  N   . LYS A 1 49  ? 48.07692  -12.31522 -30.04991 1.000 34.96974  ?  49  LYS A N   1 
ATOM   168  C  CA  . LYS A 1 49  ? 46.68552  -11.94100 -29.84716 1.000 31.09775  ?  49  LYS A CA  1 
ATOM   169  C  C   . LYS A 1 49  ? 46.39226  -11.75306 -28.36395 1.000 26.68921  ?  49  LYS A C   1 
ATOM   170  O  O   . LYS A 1 49  ? 47.06309  -12.31971 -27.49657 1.000 26.83009  ?  49  LYS A O   1 
ATOM   171  C  CB  . LYS A 1 49  ? 45.75331  -13.00225 -30.43306 1.000 27.24565  ?  49  LYS A CB  1 
ATOM   172  C  CG  . LYS A 1 49  ? 45.75863  -14.31510 -29.66891 1.000 18.65446  ?  49  LYS A CG  1 
ATOM   173  C  CD  . LYS A 1 49  ? 44.96465  -15.38823 -30.39121 1.000 19.88728  ?  49  LYS A CD  1 
ATOM   174  C  CE  . LYS A 1 49  ? 44.94949  -16.68010 -29.59004 1.000 27.36657  ?  49  LYS A CE  1 
ATOM   175  N  NZ  . LYS A 1 49  ? 44.37333  -17.81841 -30.35664 1.000 17.99225  ?  49  LYS A NZ  1 
ATOM   176  N  N   . LEU A 1 50  ? 45.38490  -10.93188 -28.07845 1.000 28.24729  ?  50  LEU A N   1 
ATOM   177  C  CA  . LEU A 1 50  ? 44.94820  -10.74137 -26.70367 1.000 26.38330  ?  50  LEU A CA  1 
ATOM   178  C  C   . LEU A 1 50  ? 44.46039  -12.06207 -26.12639 1.000 29.90268  ?  50  LEU A C   1 
ATOM   179  O  O   . LEU A 1 50  ? 43.67632  -12.77787 -26.75647 1.000 37.40206  ?  50  LEU A O   1 
ATOM   180  C  CB  . LEU A 1 50  ? 43.83592  -9.69687  -26.63903 1.000 20.72728  ?  50  LEU A CB  1 
ATOM   181  C  CG  . LEU A 1 50  ? 43.26804  -9.45721  -25.23935 1.000 21.70067  ?  50  LEU A CG  1 
ATOM   182  C  CD1 . LEU A 1 50  ? 44.12409  -8.46111  -24.47122 1.000 25.55417  ?  50  LEU A CD1 1 
ATOM   183  C  CD2 . LEU A 1 50  ? 41.81809  -9.00647  -25.29745 1.000 15.91026  ?  50  LEU A CD2 1 
ATOM   184  N  N   . GLY A 1 51  ? 44.92383  -12.38141 -24.92191 1.000 29.26186  ?  51  GLY A N   1 
ATOM   185  C  CA  . GLY A 1 51  ? 44.55133  -13.61497 -24.26912 1.000 28.43367  ?  51  GLY A CA  1 
ATOM   186  C  C   . GLY A 1 51  ? 45.45516  -14.79605 -24.53742 1.000 36.11261  ?  51  GLY A C   1 
ATOM   187  O  O   . GLY A 1 51  ? 45.20429  -15.87617 -23.99098 1.000 38.58924  ?  51  GLY A O   1 
ATOM   188  N  N   . ALA A 1 52  ? 46.49709  -14.63399 -25.35772 1.000 37.62638  ?  52  ALA A N   1 
ATOM   189  C  CA  . ALA A 1 52  ? 47.41052  -15.74461 -25.61091 1.000 33.45401  ?  52  ALA A CA  1 
ATOM   190  C  C   . ALA A 1 52  ? 48.09397  -16.20988 -24.33201 1.000 27.47918  ?  52  ALA A C   1 
ATOM   191  O  O   . ALA A 1 52  ? 48.43924  -17.38985 -24.20325 1.000 24.25669  ?  52  ALA A O   1 
ATOM   192  C  CB  . ALA A 1 52  ? 48.45117  -15.34260 -26.65416 1.000 24.93477  ?  52  ALA A CB  1 
ATOM   193  N  N   . LYS A 1 53  ? 48.28503  -15.30262 -23.37532 1.000 28.47685  ?  53  LYS A N   1 
ATOM   194  C  CA  . LYS A 1 53  ? 48.88569  -15.63247 -22.09036 1.000 28.03455  ?  53  LYS A CA  1 
ATOM   195  C  C   . LYS A 1 53  ? 48.01217  -16.54665 -21.23930 1.000 31.75529  ?  53  LYS A C   1 
ATOM   196  O  O   . LYS A 1 53  ? 48.50409  -17.09329 -20.24587 1.000 26.40828  ?  53  LYS A O   1 
ATOM   197  C  CB  . LYS A 1 53  ? 49.18221  -14.33793 -21.33471 1.000 33.75824  ?  53  LYS A CB  1 
ATOM   198  C  CG  . LYS A 1 53  ? 48.04629  -13.32667 -21.42368 1.000 28.85808  ?  53  LYS A CG  1 
ATOM   199  C  CD  . LYS A 1 53  ? 48.54818  -11.90104 -21.28644 1.000 48.07679  ?  53  LYS A CD  1 
ATOM   200  C  CE  . LYS A 1 53  ? 47.44937  -10.89813 -21.60652 1.000 49.67933  ?  53  LYS A CE  1 
ATOM   201  N  NZ  . LYS A 1 53  ? 46.91948  -11.05706 -22.99048 1.000 23.83957  ?  53  LYS A NZ  1 
ATOM   202  N  N   . ILE A 1 54  ? 46.74012  -16.72339 -21.59803 1.000 38.77079  ?  54  ILE A N   1 
ATOM   203  C  CA  . ILE A 1 54  ? 45.83280  -17.53654 -20.79701 1.000 36.88849  ?  54  ILE A CA  1 
ATOM   204  C  C   . ILE A 1 54  ? 46.23046  -19.00249 -20.89441 1.000 37.16787  ?  54  ILE A C   1 
ATOM   205  O  O   . ILE A 1 54  ? 46.44796  -19.53491 -21.99088 1.000 40.72478  ?  54  ILE A O   1 
ATOM   206  C  CB  . ILE A 1 54  ? 44.37961  -17.32719 -21.24976 1.000 31.18836  ?  54  ILE A CB  1 
ATOM   207  C  CG1 . ILE A 1 54  ? 43.89113  -15.92995 -20.86426 1.000 28.81454  ?  54  ILE A CG1 1 
ATOM   208  C  CG2 . ILE A 1 54  ? 43.47115  -18.39218 -20.65224 1.000 31.44506  ?  54  ILE A CG2 1 
ATOM   209  C  CD1 . ILE A 1 54  ? 43.72974  -15.73268 -19.37404 1.000 25.60759  ?  54  ILE A CD1 1 
ATOM   210  N  N   . VAL A 1 55  ? 46.33033  -19.66076 -19.74253 1.000 38.97674  ?  55  VAL A N   1 
ATOM   211  C  CA  . VAL A 1 55  ? 46.51213  -21.10466 -19.65845 1.000 35.10056  ?  55  VAL A CA  1 
ATOM   212  C  C   . VAL A 1 55  ? 45.21649  -21.70637 -19.13439 1.000 36.57591  ?  55  VAL A C   1 
ATOM   213  O  O   . VAL A 1 55  ? 44.66019  -21.22932 -18.13712 1.000 37.91658  ?  55  VAL A O   1 
ATOM   214  C  CB  . VAL A 1 55  ? 47.70535  -21.47979 -18.76232 1.000 29.18165  ?  55  VAL A CB  1 
ATOM   215  C  CG1 . VAL A 1 55  ? 49.00845  -21.33438 -19.53125 1.000 28.46182  ?  55  VAL A CG1 1 
ATOM   216  C  CG2 . VAL A 1 55  ? 47.72502  -20.61427 -17.51008 1.000 35.90553  ?  55  VAL A CG2 1 
ATOM   217  N  N   . LEU A 1 56  ? 44.72928  -22.73903 -19.81349 1.000 30.89743  ?  56  LEU A N   1 
ATOM   218  C  CA  . LEU A 1 56  ? 43.44898  -23.35375 -19.49330 1.000 32.33007  ?  56  LEU A CA  1 
ATOM   219  C  C   . LEU A 1 56  ? 43.66779  -24.68139 -18.78146 1.000 28.90909  ?  56  LEU A C   1 
ATOM   220  O  O   . LEU A 1 56  ? 44.50855  -25.48489 -19.19896 1.000 23.84344  ?  56  LEU A O   1 
ATOM   221  C  CB  . LEU A 1 56  ? 42.61871  -23.57611 -20.75961 1.000 40.70002  ?  56  LEU A CB  1 
ATOM   222  C  CG  . LEU A 1 56  ? 42.17625  -22.35289 -21.56481 1.000 38.62429  ?  56  LEU A CG  1 
ATOM   223  C  CD1 . LEU A 1 56  ? 41.42658  -22.78581 -22.81651 1.000 30.68673  ?  56  LEU A CD1 1 
ATOM   224  C  CD2 . LEU A 1 56  ? 41.31488  -21.43246 -20.71593 1.000 37.79157  ?  56  LEU A CD2 1 
ATOM   225  N  N   . THR A 1 57  ? 42.91239  -24.90691 -17.70937 1.000 34.90062  ?  57  THR A N   1 
ATOM   226  C  CA  . THR A 1 57  ? 42.84219  -26.23734 -17.13085 1.000 37.67168  ?  57  THR A CA  1 
ATOM   227  C  C   . THR A 1 57  ? 42.13076  -27.17781 -18.10228 1.000 42.73326  ?  57  THR A C   1 
ATOM   228  O  O   . THR A 1 57  ? 41.55840  -26.75545 -19.10983 1.000 41.49334  ?  57  THR A O   1 
ATOM   229  C  CB  . THR A 1 57  ? 42.12132  -26.20923 -15.78230 1.000 27.75687  ?  57  THR A CB  1 
ATOM   230  O  OG1 . THR A 1 57  ? 40.75756  -25.81208 -15.97142 1.000 25.03176  ?  57  THR A OG1 1 
ATOM   231  C  CG2 . THR A 1 57  ? 42.80210  -25.23182 -14.83461 1.000 25.70543  ?  57  THR A CG2 1 
ATOM   232  N  N   . ASN A 1 58  ? 42.17469  -28.47491 -17.79257 1.000 41.65408  ?  58  ASN A N   1 
ATOM   233  C  CA  . ASN A 1 58  ? 41.62198  -29.46664 -18.71123 1.000 36.93191  ?  58  ASN A CA  1 
ATOM   234  C  C   . ASN A 1 58  ? 40.12689  -29.25344 -18.92671 1.000 36.72452  ?  58  ASN A C   1 
ATOM   235  O  O   . ASN A 1 58  ? 39.63276  -29.36448 -20.05473 1.000 38.71958  ?  58  ASN A O   1 
ATOM   236  C  CB  . ASN A 1 58  ? 41.90330  -30.87596 -18.19025 1.000 47.32086  ?  58  ASN A CB  1 
ATOM   237  C  CG  . ASN A 1 58  ? 43.38547  -31.21348 -18.18841 1.000 51.74591  ?  58  ASN A CG  1 
ATOM   238  O  OD1 . ASN A 1 58  ? 44.23896  -30.32631 -18.23044 1.000 42.11267  ?  58  ASN A OD1 1 
ATOM   239  N  ND2 . ASN A 1 58  ? 43.69708  -32.50386 -18.14079 1.000 62.12855  ?  58  ASN A ND2 1 
ATOM   240  N  N   . GLU A 1 59  ? 39.39152  -28.94168 -17.85714 1.000 35.28162  ?  59  GLU A N   1 
ATOM   241  C  CA  . GLU A 1 59  ? 37.96868  -28.63858 -17.99080 1.000 35.63320  ?  59  GLU A CA  1 
ATOM   242  C  C   . GLU A 1 59  ? 37.75014  -27.37334 -18.81552 1.000 40.44721  ?  59  GLU A C   1 
ATOM   243  O  O   . GLU A 1 59  ? 36.82741  -27.30180 -19.64403 1.000 36.64625  ?  59  GLU A O   1 
ATOM   244  C  CB  . GLU A 1 59  ? 37.33875  -28.49338 -16.60408 1.000 36.37209  ?  59  GLU A CB  1 
ATOM   245  C  CG  . GLU A 1 59  ? 37.58597  -29.66818 -15.66397 1.000 35.10119  ?  59  GLU A CG  1 
ATOM   246  C  CD  . GLU A 1 59  ? 38.91377  -29.57165 -14.93319 1.000 44.82081  ?  59  GLU A CD  1 
ATOM   247  O  OE1 . GLU A 1 59  ? 39.54058  -28.49145 -14.97281 1.000 50.01999  ?  59  GLU A OE1 1 
ATOM   248  O  OE2 . GLU A 1 59  ? 39.33082  -30.57708 -14.32049 1.000 53.51245  -1 59  GLU A OE2 1 
ATOM   249  N  N   . GLU A 1 60  ? 38.58539  -26.35695 -18.59120 1.000 40.38089  ?  60  GLU A N   1 
ATOM   250  C  CA  . GLU A 1 60  ? 38.51152  -25.15182 -19.40587 1.000 35.31082  ?  60  GLU A CA  1 
ATOM   251  C  C   . GLU A 1 60  ? 38.78870  -25.46968 -20.86772 1.000 40.56716  ?  60  GLU A C   1 
ATOM   252  O  O   . GLU A 1 60  ? 38.17187  -24.88551 -21.76293 1.000 50.27648  ?  60  GLU A O   1 
ATOM   253  C  CB  . GLU A 1 60  ? 39.48617  -24.09879 -18.87856 1.000 37.00186  ?  60  GLU A CB  1 
ATOM   254  C  CG  . GLU A 1 60  ? 39.07321  -23.50019 -17.54034 1.000 40.49207  ?  60  GLU A CG  1 
ATOM   255  C  CD  . GLU A 1 60  ? 39.97661  -22.36494 -17.09664 1.000 34.52877  ?  60  GLU A CD  1 
ATOM   256  O  OE1 . GLU A 1 60  ? 41.20562  -22.46402 -17.29550 1.000 30.94096  ?  60  GLU A OE1 1 
ATOM   257  O  OE2 . GLU A 1 60  ? 39.45402  -21.36889 -16.55300 1.000 27.43829  -1 60  GLU A OE2 1 
ATOM   258  N  N   . LYS A 1 61  ? 39.70460  -26.40554 -21.12986 1.000 38.03250  ?  61  LYS A N   1 
ATOM   259  C  CA  . LYS A 1 61  ? 39.93905  -26.84294 -22.50163 1.000 36.08975  ?  61  LYS A CA  1 
ATOM   260  C  C   . LYS A 1 61  ? 38.74083  -27.59597 -23.06401 1.000 34.13933  ?  61  LYS A C   1 
ATOM   261  O  O   . LYS A 1 61  ? 38.47724  -27.51753 -24.26638 1.000 35.56182  ?  61  LYS A O   1 
ATOM   262  C  CB  . LYS A 1 61  ? 41.19795  -27.70605 -22.57722 1.000 32.71967  ?  61  LYS A CB  1 
ATOM   263  C  CG  . LYS A 1 61  ? 42.48942  -26.90766 -22.54053 1.000 27.92477  ?  61  LYS A CG  1 
ATOM   264  C  CD  . LYS A 1 61  ? 43.70208  -27.81487 -22.45628 1.000 28.12700  ?  61  LYS A CD  1 
ATOM   265  C  CE  . LYS A 1 61  ? 44.97737  -27.00603 -22.29335 1.000 41.91066  ?  61  LYS A CE  1 
ATOM   266  N  NZ  . LYS A 1 61  ? 46.15288  -27.87399 -22.01023 1.000 55.99308  ?  61  LYS A NZ  1 
ATOM   267  N  N   . VAL A 1 62  ? 38.00675  -28.32566 -22.22113 1.000 34.41816  ?  62  VAL A N   1 
ATOM   268  C  CA  . VAL A 1 62  ? 36.77607  -28.97034 -22.67804 1.000 30.12335  ?  62  VAL A CA  1 
ATOM   269  C  C   . VAL A 1 62  ? 35.77800  -27.92038 -23.15010 1.000 32.23602  ?  62  VAL A C   1 
ATOM   270  O  O   . VAL A 1 62  ? 35.19133  -28.02962 -24.23614 1.000 39.50485  ?  62  VAL A O   1 
ATOM   271  C  CB  . VAL A 1 62  ? 36.18169  -29.84729 -21.56072 1.000 26.17885  ?  62  VAL A CB  1 
ATOM   272  C  CG1 . VAL A 1 62  ? 34.79025  -30.32937 -21.94438 1.000 25.43064  ?  62  VAL A CG1 1 
ATOM   273  C  CG2 . VAL A 1 62  ? 37.09701  -31.02519 -21.26284 1.000 39.93244  ?  62  VAL A CG2 1 
ATOM   274  N  N   . LEU A 1 63  ? 35.58557  -26.87550 -22.34219 1.000 31.83027  ?  63  LEU A N   1 
ATOM   275  C  CA  . LEU A 1 63  ? 34.66958  -25.80317 -22.73337 1.000 29.30898  ?  63  LEU A CA  1 
ATOM   276  C  C   . LEU A 1 63  ? 35.16856  -25.07179 -23.97750 1.000 26.65139  ?  63  LEU A C   1 
ATOM   277  O  O   . LEU A 1 63  ? 34.37707  -24.70547 -24.86035 1.000 27.93730  ?  63  LEU A O   1 
ATOM   278  C  CB  . LEU A 1 63  ? 34.47378  -24.82819 -21.57321 1.000 24.19110  ?  63  LEU A CB  1 
ATOM   279  C  CG  . LEU A 1 63  ? 33.44807  -25.27141 -20.52910 1.000 20.13367  ?  63  LEU A CG  1 
ATOM   280  C  CD1 . LEU A 1 63  ? 33.37546  -24.27981 -19.38003 1.000 23.98931  ?  63  LEU A CD1 1 
ATOM   281  C  CD2 . LEU A 1 63  ? 32.08550  -25.44380 -21.17975 1.000 17.92595  ?  63  LEU A CD2 1 
ATOM   282  N  N   . ASP A 1 64  ? 36.48198  -24.85197 -24.06214 1.000 24.30795  ?  64  ASP A N   1 
ATOM   283  C  CA  . ASP A 1 64  ? 37.06197  -24.18913 -25.22344 1.000 22.83471  ?  64  ASP A CA  1 
ATOM   284  C  C   . ASP A 1 64  ? 36.84489  -25.00380 -26.49064 1.000 22.56494  ?  64  ASP A C   1 
ATOM   285  O  O   . ASP A 1 64  ? 36.53361  -24.44477 -27.54460 1.000 22.99857  ?  64  ASP A O   1 
ATOM   286  C  CB  . ASP A 1 64  ? 38.55255  -23.94345 -24.98978 1.000 27.13655  ?  64  ASP A CB  1 
ATOM   287  C  CG  . ASP A 1 64  ? 39.24899  -23.37805 -26.21004 1.000 28.88801  ?  64  ASP A CG  1 
ATOM   288  O  OD1 . ASP A 1 64  ? 39.11946  -22.16185 -26.45978 1.000 28.01231  ?  64  ASP A OD1 1 
ATOM   289  O  OD2 . ASP A 1 64  ? 39.92592  -24.15098 -26.92090 1.000 28.77004  -1 64  ASP A OD2 1 
ATOM   290  N  N   . ASP A 1 65  ? 37.01311  -26.32606 -26.41032 1.000 27.94172  ?  65  ASP A N   1 
ATOM   291  C  CA  . ASP A 1 65  ? 36.73940  -27.18173 -27.56044 1.000 31.71154  ?  65  ASP A CA  1 
ATOM   292  C  C   . ASP A 1 65  ? 35.26377  -27.14463 -27.93017 1.000 30.55761  ?  65  ASP A C   1 
ATOM   293  O  O   . ASP A 1 65  ? 34.91263  -27.14305 -29.11728 1.000 28.63710  ?  65  ASP A O   1 
ATOM   294  C  CB  . ASP A 1 65  ? 37.17914  -28.61711 -27.27046 1.000 36.80187  ?  65  ASP A CB  1 
ATOM   295  C  CG  . ASP A 1 65  ? 38.67625  -28.74128 -27.07470 1.000 47.47571  ?  65  ASP A CG  1 
ATOM   296  O  OD1 . ASP A 1 65  ? 39.41449  -27.84231 -27.52990 1.000 41.45898  ?  65  ASP A OD1 1 
ATOM   297  O  OD2 . ASP A 1 65  ? 39.11494  -29.74229 -26.46935 1.000 69.32350  -1 65  ASP A OD2 1 
ATOM   298  N  N   . PHE A 1 66  ? 34.38496  -27.12234 -26.92379 1.000 28.24817  ?  66  PHE A N   1 
ATOM   299  C  CA  . PHE A 1 66  ? 32.95292  -27.02826 -27.19076 1.000 22.36176  ?  66  PHE A CA  1 
ATOM   300  C  C   . PHE A 1 66  ? 32.62978  -25.77304 -27.99270 1.000 27.84377  ?  66  PHE A C   1 
ATOM   301  O  O   . PHE A 1 66  ? 31.86376  -25.81950 -28.96232 1.000 22.30764  ?  66  PHE A O   1 
ATOM   302  C  CB  . PHE A 1 66  ? 32.17695  -27.04341 -25.87281 1.000 25.55076  ?  66  PHE A CB  1 
ATOM   303  C  CG  . PHE A 1 66  ? 30.68314  -27.04352 -26.04431 1.000 39.64561  ?  66  PHE A CG  1 
ATOM   304  C  CD1 . PHE A 1 66  ? 29.98976  -28.23470 -26.17083 1.000 41.91158  ?  66  PHE A CD1 1 
ATOM   305  C  CD2 . PHE A 1 66  ? 29.97076  -25.85457 -26.06848 1.000 38.16227  ?  66  PHE A CD2 1 
ATOM   306  C  CE1 . PHE A 1 66  ? 28.61829  -28.24068 -26.32404 1.000 31.50084  ?  66  PHE A CE1 1 
ATOM   307  C  CE2 . PHE A 1 66  ? 28.59684  -25.85598 -26.22459 1.000 29.49926  ?  66  PHE A CE2 1 
ATOM   308  C  CZ  . PHE A 1 66  ? 27.92076  -27.05017 -26.35158 1.000 33.18526  ?  66  PHE A CZ  1 
ATOM   309  N  N   . ILE A 1 67  ? 33.21265  -24.63826 -27.60095 1.000 33.43755  ?  67  ILE A N   1 
ATOM   310  C  CA  . ILE A 1 67  ? 32.96754  -23.39069 -28.32498 1.000 25.61464  ?  67  ILE A CA  1 
ATOM   311  C  C   . ILE A 1 67  ? 33.63323  -23.41816 -29.70110 1.000 26.07208  ?  67  ILE A C   1 
ATOM   312  O  O   . ILE A 1 67  ? 33.05610  -22.95572 -30.69968 1.000 28.69570  ?  67  ILE A O   1 
ATOM   313  C  CB  . ILE A 1 67  ? 33.44187  -22.19200 -27.48430 1.000 22.44158  ?  67  ILE A CB  1 
ATOM   314  C  CG1 . ILE A 1 67  ? 32.65789  -22.12560 -26.17147 1.000 22.06232  ?  67  ILE A CG1 1 
ATOM   315  C  CG2 . ILE A 1 67  ? 33.29458  -20.89632 -28.26493 1.000 22.87308  ?  67  ILE A CG2 1 
ATOM   316  C  CD1 . ILE A 1 67  ? 33.09447  -21.00523 -25.25346 1.000 21.33800  ?  67  ILE A CD1 1 
ATOM   317  N  N   . LEU A 1 68  ? 34.85542  -23.95671 -29.77183 1.000 21.98536  ?  68  LEU A N   1 
ATOM   318  C  CA  . LEU A 1 68  ? 35.61320  -23.97882 -31.01763 1.000 19.10290  ?  68  LEU A CA  1 
ATOM   319  C  C   . LEU A 1 68  ? 34.90686  -24.79734 -32.08421 1.000 23.84829  ?  68  LEU A C   1 
ATOM   320  O  O   . LEU A 1 68  ? 34.92896  -24.43381 -33.26286 1.000 19.36892  ?  68  LEU A O   1 
ATOM   321  C  CB  . LEU A 1 68  ? 37.01421  -24.54122 -30.77302 1.000 22.90844  ?  68  LEU A CB  1 
ATOM   322  C  CG  . LEU A 1 68  ? 38.14817  -23.57694 -30.42655 1.000 20.76168  ?  68  LEU A CG  1 
ATOM   323  C  CD1 . LEU A 1 68  ? 39.42470  -24.33984 -30.10063 1.000 17.86247  ?  68  LEU A CD1 1 
ATOM   324  C  CD2 . LEU A 1 68  ? 38.38314  -22.59431 -31.56395 1.000 18.59440  ?  68  LEU A CD2 1 
ATOM   325  N  N   . ALA A 1 69  ? 34.29565  -25.91888 -31.69672 1.000 31.93417  ?  69  ALA A N   1 
ATOM   326  C  CA  . ALA A 1 69  ? 33.60276  -26.75143 -32.67510 1.000 30.77435  ?  69  ALA A CA  1 
ATOM   327  C  C   . ALA A 1 69  ? 32.51705  -25.95995 -33.39376 1.000 18.14152  ?  69  ALA A C   1 
ATOM   328  O  O   . ALA A 1 69  ? 32.46964  -25.92667 -34.62923 1.000 19.50244  ?  69  ALA A O   1 
ATOM   329  C  CB  . ALA A 1 69  ? 33.01087  -27.98426 -31.99109 1.000 29.63114  ?  69  ALA A CB  1 
ATOM   330  N  N   . GLU A 1 70  ? 31.65006  -25.29059 -32.63066 1.000 17.81865  ?  70  GLU A N   1 
ATOM   331  C  CA  . GLU A 1 70  ? 30.56630  -24.52548 -33.23814 1.000 21.82139  ?  70  GLU A CA  1 
ATOM   332  C  C   . GLU A 1 70  ? 31.10106  -23.35757 -34.05696 1.000 21.06938  ?  70  GLU A C   1 
ATOM   333  O  O   . GLU A 1 70  ? 30.64472  -23.11802 -35.18548 1.000 19.16299  ?  70  GLU A O   1 
ATOM   334  C  CB  . GLU A 1 70  ? 29.60423  -24.03090 -32.15781 1.000 17.13385  ?  70  GLU A CB  1 
ATOM   335  C  CG  . GLU A 1 70  ? 28.56760  -23.03999 -32.65770 1.000 18.71162  ?  70  GLU A CG  1 
ATOM   336  C  CD  . GLU A 1 70  ? 27.34858  -22.97431 -31.76132 1.000 22.07764  ?  70  GLU A CD  1 
ATOM   337  O  OE1 . GLU A 1 70  ? 26.60954  -23.97851 -31.69186 1.000 18.08241  ?  70  GLU A OE1 1 
ATOM   338  O  OE2 . GLU A 1 70  ? 27.13326  -21.92397 -31.12048 1.000 26.37128  -1 70  GLU A OE2 1 
ATOM   339  N  N   . LYS A 1 71  ? 32.07132  -22.61644 -33.50932 1.000 24.48556  ?  71  LYS A N   1 
ATOM   340  C  CA  . LYS A 1 71  ? 32.58607  -21.45868 -34.23542 1.000 22.84971  ?  71  LYS A CA  1 
ATOM   341  C  C   . LYS A 1 71  ? 33.24313  -21.87504 -35.54583 1.000 19.26523  ?  71  LYS A C   1 
ATOM   342  O  O   . LYS A 1 71  ? 33.02927  -21.24052 -36.58653 1.000 19.03896  ?  71  LYS A O   1 
ATOM   343  C  CB  . LYS A 1 71  ? 33.57216  -20.67662 -33.36942 1.000 24.42526  ?  71  LYS A CB  1 
ATOM   344  C  CG  . LYS A 1 71  ? 34.21247  -19.50822 -34.10180 1.000 21.23949  ?  71  LYS A CG  1 
ATOM   345  C  CD  . LYS A 1 71  ? 35.13516  -18.71245 -33.20118 1.000 18.93968  ?  71  LYS A CD  1 
ATOM   346  C  CE  . LYS A 1 71  ? 35.85547  -17.63113 -33.98486 1.000 17.91594  ?  71  LYS A CE  1 
ATOM   347  N  NZ  . LYS A 1 71  ? 36.76309  -16.84495 -33.11263 1.000 21.21203  ?  71  LYS A NZ  1 
ATOM   348  N  N   . ARG A 1 72  ? 34.03547  -22.94842 -35.51823 1.000 15.00852  ?  72  ARG A N   1 
ATOM   349  C  CA  . ARG A 1 72  ? 34.71053  -23.41065 -36.72273 1.000 15.47594  ?  72  ARG A CA  1 
ATOM   350  C  C   . ARG A 1 72  ? 33.72213  -23.97843 -37.73042 1.000 16.90073  ?  72  ARG A C   1 
ATOM   351  O  O   . ARG A 1 72  ? 33.89276  -23.78890 -38.93980 1.000 17.84825  ?  72  ARG A O   1 
ATOM   352  C  CB  . ARG A 1 72  ? 35.77404  -24.44357 -36.35624 1.000 16.18374  ?  72  ARG A CB  1 
ATOM   353  C  CG  . ARG A 1 72  ? 36.98652  -23.83521 -35.67691 1.000 17.91662  ?  72  ARG A CG  1 
ATOM   354  C  CD  . ARG A 1 72  ? 37.83648  -24.88140 -34.98252 1.000 16.63591  ?  72  ARG A CD  1 
ATOM   355  N  NE  . ARG A 1 72  ? 39.11430  -24.32456 -34.55603 1.000 16.43705  ?  72  ARG A NE  1 
ATOM   356  C  CZ  . ARG A 1 72  ? 39.94972  -24.91871 -33.71597 1.000 15.19925  ?  72  ARG A CZ  1 
ATOM   357  N  NH1 . ARG A 1 72  ? 39.66180  -26.08647 -33.16520 1.000 20.29060  ?  72  ARG A NH1 1 
ATOM   358  N  NH2 . ARG A 1 72  ? 41.10109  -24.32375 -33.41741 1.000 16.71699  ?  72  ARG A NH2 1 
ATOM   359  N  N   . LYS A 1 73  ? 32.67951  -24.67124 -37.26082 1.000 16.64526  ?  73  LYS A N   1 
ATOM   360  C  CA  . LYS A 1 73  ? 31.65479  -25.14621 -38.18338 1.000 14.79821  ?  73  LYS A CA  1 
ATOM   361  C  C   . LYS A 1 73  ? 30.98900  -23.97902 -38.89571 1.000 19.00871  ?  73  LYS A C   1 
ATOM   362  O  O   . LYS A 1 73  ? 30.81374  -24.00401 -40.11840 1.000 22.85271  ?  73  LYS A O   1 
ATOM   363  C  CB  . LYS A 1 73  ? 30.60988  -25.98259 -37.44590 1.000 18.25246  ?  73  LYS A CB  1 
ATOM   364  C  CG  . LYS A 1 73  ? 29.44608  -26.40400 -38.33585 1.000 18.61056  ?  73  LYS A CG  1 
ATOM   365  C  CD  . LYS A 1 73  ? 28.34093  -27.08841 -37.54757 1.000 30.55582  ?  73  LYS A CD  1 
ATOM   366  C  CE  . LYS A 1 73  ? 27.66373  -26.12654 -36.58488 1.000 22.03357  ?  73  LYS A CE  1 
ATOM   367  N  NZ  . LYS A 1 73  ? 26.54081  -26.77707 -35.85318 1.000 28.27985  ?  73  LYS A NZ  1 
ATOM   368  N  N   . LEU A 1 74  ? 30.62696  -22.93397 -38.14596 1.000 17.52507  ?  74  LEU A N   1 
ATOM   369  C  CA  . LEU A 1 74  ? 29.99759  -21.77363 -38.77088 1.000 16.42559  ?  74  LEU A CA  1 
ATOM   370  C  C   . LEU A 1 74  ? 30.94202  -21.09214 -39.75631 1.000 17.56114  ?  74  LEU A C   1 
ATOM   371  O  O   . LEU A 1 74  ? 30.54190  -20.75066 -40.87874 1.000 17.34971  ?  74  LEU A O   1 
ATOM   372  C  CB  . LEU A 1 74  ? 29.52893  -20.78976 -37.69945 1.000 9.54990   ?  74  LEU A CB  1 
ATOM   373  C  CG  . LEU A 1 74  ? 28.41632  -21.30874 -36.78651 1.000 9.04041   ?  74  LEU A CG  1 
ATOM   374  C  CD1 . LEU A 1 74  ? 27.93815  -20.22161 -35.83779 1.000 13.55592  ?  74  LEU A CD1 1 
ATOM   375  C  CD2 . LEU A 1 74  ? 27.25986  -21.85458 -37.60893 1.000 11.86520  ?  74  LEU A CD2 1 
ATOM   376  N  N   . ILE A 1 75  ? 32.20553  -20.90696 -39.36302 1.000 16.87873  ?  75  ILE A N   1 
ATOM   377  C  CA  . ILE A 1 75  ? 33.16558  -20.22229 -40.22647 1.000 17.54230  ?  75  ILE A CA  1 
ATOM   378  C  C   . ILE A 1 75  ? 33.37251  -21.00241 -41.51885 1.000 16.72752  ?  75  ILE A C   1 
ATOM   379  O  O   . ILE A 1 75  ? 33.34268  -20.43578 -42.61739 1.000 18.02541  ?  75  ILE A O   1 
ATOM   380  C  CB  . ILE A 1 75  ? 34.49551  -20.00050 -39.48265 1.000 11.89197  ?  75  ILE A CB  1 
ATOM   381  C  CG1 . ILE A 1 75  ? 34.32900  -18.94557 -38.38770 1.000 11.62269  ?  75  ILE A CG1 1 
ATOM   382  C  CG2 . ILE A 1 75  ? 35.59165  -19.59318 -40.45343 1.000 11.84917  ?  75  ILE A CG2 1 
ATOM   383  C  CD1 . ILE A 1 75  ? 35.58294  -18.71043 -37.57355 1.000 14.19218  ?  75  ILE A CD1 1 
ATOM   384  N  N   . ASP A 1 76  ? 33.57211  -22.31806 -41.40922 1.000 16.74746  ?  76  ASP A N   1 
ATOM   385  C  CA  . ASP A 1 76  ? 33.83914  -23.12454 -42.59499 1.000 20.47560  ?  76  ASP A CA  1 
ATOM   386  C  C   . ASP A 1 76  ? 32.60010  -23.25117 -43.47328 1.000 24.17374  ?  76  ASP A C   1 
ATOM   387  O  O   . ASP A 1 76  ? 32.70679  -23.25439 -44.70556 1.000 20.17713  ?  76  ASP A O   1 
ATOM   388  C  CB  . ASP A 1 76  ? 34.35863  -24.50141 -42.18296 1.000 19.50619  ?  76  ASP A CB  1 
ATOM   389  C  CG  . ASP A 1 76  ? 35.68514  -24.42740 -41.44764 1.000 20.59337  ?  76  ASP A CG  1 
ATOM   390  O  OD1 . ASP A 1 76  ? 36.26029  -23.32142 -41.35880 1.000 15.40368  ?  76  ASP A OD1 1 
ATOM   391  O  OD2 . ASP A 1 76  ? 36.15275  -25.47584 -40.95628 1.000 28.03126  -1 76  ASP A OD2 1 
ATOM   392  N  N   . ASP A 1 77  ? 31.41573  -23.35433 -42.86255 1.000 22.91437  ?  77  ASP A N   1 
ATOM   393  C  CA  . ASP A 1 77  ? 30.18555  -23.41000 -43.64199 1.000 22.97246  ?  77  ASP A CA  1 
ATOM   394  C  C   . ASP A 1 77  ? 29.97962  -22.12258 -44.42700 1.000 22.34203  ?  77  ASP A C   1 
ATOM   395  O  O   . ASP A 1 77  ? 29.57207  -22.15645 -45.59349 1.000 26.19775  ?  77  ASP A O   1 
ATOM   396  C  CB  . ASP A 1 77  ? 28.99677  -23.67831 -42.71743 1.000 26.01628  ?  77  ASP A CB  1 
ATOM   397  C  CG  . ASP A 1 77  ? 27.72547  -24.01240 -43.47639 1.000 29.55165  ?  77  ASP A CG  1 
ATOM   398  O  OD1 . ASP A 1 77  ? 27.79339  -24.19953 -44.70867 1.000 27.01044  ?  77  ASP A OD1 1 
ATOM   399  O  OD2 . ASP A 1 77  ? 26.65468  -24.08825 -42.83737 1.000 26.91897  -1 77  ASP A OD2 1 
ATOM   400  N  N   . SER A 1 78  ? 30.25461  -20.97403 -43.80536 1.000 20.52866  ?  78  SER A N   1 
ATOM   401  C  CA  . SER A 1 78  ? 30.14294  -19.71442 -44.53235 1.000 20.56221  ?  78  SER A CA  1 
ATOM   402  C  C   . SER A 1 78  ? 31.19909  -19.60552 -45.62750 1.000 21.72153  ?  78  SER A C   1 
ATOM   403  O  O   . SER A 1 78  ? 30.89934  -19.16383 -46.74299 1.000 22.82133  ?  78  SER A O   1 
ATOM   404  C  CB  . SER A 1 78  ? 30.25208  -18.53786 -43.56496 1.000 21.91903  ?  78  SER A CB  1 
ATOM   405  O  OG  . SER A 1 78  ? 30.19724  -17.30615 -44.26258 1.000 23.47105  ?  78  SER A OG  1 
ATOM   406  N  N   . ARG A 1 79  ? 32.43887  -20.00505 -45.33062 1.000 21.51129  ?  79  ARG A N   1 
ATOM   407  C  CA  . ARG A 1 79  ? 33.53986  -19.77716 -46.26251 1.000 18.74163  ?  79  ARG A CA  1 
ATOM   408  C  C   . ARG A 1 79  ? 33.45368  -20.69315 -47.47794 1.000 20.79887  ?  79  ARG A C   1 
ATOM   409  O  O   . ARG A 1 79  ? 33.54665  -20.23256 -48.62234 1.000 19.37653  ?  79  ARG A O   1 
ATOM   410  C  CB  . ARG A 1 79  ? 34.87705  -19.96992 -45.54426 1.000 13.27401  ?  79  ARG A CB  1 
ATOM   411  C  CG  . ARG A 1 79  ? 36.08383  -19.94054 -46.46941 1.000 14.25934  ?  79  ARG A CG  1 
ATOM   412  C  CD  . ARG A 1 79  ? 37.39375  -19.95848 -45.69504 1.000 13.75554  ?  79  ARG A CD  1 
ATOM   413  N  NE  . ARG A 1 79  ? 37.81162  -21.30216 -45.31153 1.000 13.92999  ?  79  ARG A NE  1 
ATOM   414  C  CZ  . ARG A 1 79  ? 38.60512  -22.07647 -46.04014 1.000 16.78631  ?  79  ARG A CZ  1 
ATOM   415  N  NH1 . ARG A 1 79  ? 39.06444  -21.68329 -47.21696 1.000 14.91335  ?  79  ARG A NH1 1 
ATOM   416  N  NH2 . ARG A 1 79  ? 38.94843  -23.27473 -45.57542 1.000 18.50819  ?  79  ARG A NH2 1 
ATOM   417  N  N   . LEU A 1 80  ? 33.27245  -21.99378 -47.25158 1.000 22.53476  ?  80  LEU A N   1 
ATOM   418  C  CA  . LEU A 1 80  ? 33.41078  -22.97656 -48.31956 1.000 22.51686  ?  80  LEU A CA  1 
ATOM   419  C  C   . LEU A 1 80  ? 32.10964  -23.21485 -49.07516 1.000 24.48189  ?  80  LEU A C   1 
ATOM   420  O  O   . LEU A 1 80  ? 32.12870  -23.37703 -50.30017 1.000 31.14089  ?  80  LEU A O   1 
ATOM   421  C  CB  . LEU A 1 80  ? 33.93796  -24.29232 -47.74345 1.000 18.78460  ?  80  LEU A CB  1 
ATOM   422  C  CG  . LEU A 1 80  ? 35.33645  -24.19323 -47.12916 1.000 11.03226  ?  80  LEU A CG  1 
ATOM   423  C  CD1 . LEU A 1 80  ? 35.62177  -25.38517 -46.23294 1.000 12.97880  ?  80  LEU A CD1 1 
ATOM   424  C  CD2 . LEU A 1 80  ? 36.39249  -24.07443 -48.21930 1.000 8.34299   ?  80  LEU A CD2 1 
ATOM   425  N  N   . ASN A 1 81  ? 30.97763  -23.23929 -48.37360 1.000 25.65843  ?  81  ASN A N   1 
ATOM   426  C  CA  . ASN A 1 81  ? 29.68625  -23.38349 -49.03233 1.000 32.63812  ?  81  ASN A CA  1 
ATOM   427  C  C   . ASN A 1 81  ? 29.18521  -22.08156 -49.64229 1.000 31.68140  ?  81  ASN A C   1 
ATOM   428  O  O   . ASN A 1 81  ? 28.14820  -22.09414 -50.31500 1.000 33.70379  ?  81  ASN A O   1 
ATOM   429  C  CB  . ASN A 1 81  ? 28.64741  -23.92217 -48.04628 1.000 36.59257  ?  81  ASN A CB  1 
ATOM   430  C  CG  . ASN A 1 81  ? 28.60447  -25.43709 -48.01216 1.000 43.66391  ?  81  ASN A CG  1 
ATOM   431  O  OD1 . ASN A 1 81  ? 28.69993  -26.09589 -49.04819 1.000 63.28853  ?  81  ASN A OD1 1 
ATOM   432  N  ND2 . ASN A 1 81  ? 28.46084  -25.99858 -46.81687 1.000 34.02330  ?  81  ASN A ND2 1 
ATOM   433  N  N   . GLN A 1 82  ? 29.89089  -20.97122 -49.41999 1.000 27.96528  ?  82  GLN A N   1 
ATOM   434  C  CA  . GLN A 1 82  ? 29.54124  -19.66634 -49.97911 1.000 21.47332  ?  82  GLN A CA  1 
ATOM   435  C  C   . GLN A 1 82  ? 28.12763  -19.25226 -49.56408 1.000 24.96362  ?  82  GLN A C   1 
ATOM   436  O  O   . GLN A 1 82  ? 27.25338  -18.98223 -50.39010 1.000 30.90001  ?  82  GLN A O   1 
ATOM   437  C  CB  . GLN A 1 82  ? 29.70562  -19.66422 -51.50284 1.000 24.09380  ?  82  GLN A CB  1 
ATOM   438  C  CG  . GLN A 1 82  ? 31.14436  -19.85826 -51.95786 1.000 34.52596  ?  82  GLN A CG  1 
ATOM   439  C  CD  . GLN A 1 82  ? 31.28881  -19.85713 -53.46677 1.000 51.87122  ?  82  GLN A CD  1 
ATOM   440  O  OE1 . GLN A 1 82  ? 30.71709  -19.01288 -54.15731 1.000 58.05536  ?  82  GLN A OE1 1 
ATOM   441  N  NE2 . GLN A 1 82  ? 32.05401  -20.81013 -53.98779 1.000 35.68215  ?  82  GLN A NE2 1 
ATOM   442  N  N   . THR A 1 83  ? 27.92146  -19.21508 -48.25011 1.000 24.46314  ?  83  THR A N   1 
ATOM   443  C  CA  . THR A 1 83  ? 26.68520  -18.73785 -47.65138 1.000 25.18443  ?  83  THR A CA  1 
ATOM   444  C  C   . THR A 1 83  ? 27.02091  -17.66873 -46.62008 1.000 26.16793  ?  83  THR A C   1 
ATOM   445  O  O   . THR A 1 83  ? 28.17174  -17.52375 -46.20004 1.000 26.09234  ?  83  THR A O   1 
ATOM   446  C  CB  . THR A 1 83  ? 25.88534  -19.87868 -47.00370 1.000 30.61850  ?  83  THR A CB  1 
ATOM   447  O  OG1 . THR A 1 83  ? 26.72688  -20.60767 -46.10087 1.000 33.38951  ?  83  THR A OG1 1 
ATOM   448  C  CG2 . THR A 1 83  ? 25.35186  -20.82480 -48.06950 1.000 28.36728  ?  83  THR A CG2 1 
ATOM   449  N  N   . GLU A 1 84  ? 26.00074  -16.91450 -46.21882 1.000 23.28685  ?  84  GLU A N   1 
ATOM   450  C  CA  . GLU A 1 84  ? 26.21612  -15.76506 -45.34923 1.000 28.12151  ?  84  GLU A CA  1 
ATOM   451  C  C   . GLU A 1 84  ? 26.70571  -16.19546 -43.97041 1.000 22.02487  ?  84  GLU A C   1 
ATOM   452  O  O   . GLU A 1 84  ? 26.27098  -17.21437 -43.42652 1.000 22.17674  ?  84  GLU A O   1 
ATOM   453  C  CB  . GLU A 1 84  ? 24.92789  -14.95496 -45.21277 1.000 25.39168  ?  84  GLU A CB  1 
ATOM   454  C  CG  . GLU A 1 84  ? 25.10939  -13.63645 -44.48000 1.000 24.37205  ?  84  GLU A CG  1 
ATOM   455  C  CD  . GLU A 1 84  ? 23.79743  -12.93706 -44.19693 1.000 31.26698  ?  84  GLU A CD  1 
ATOM   456  O  OE1 . GLU A 1 84  ? 22.74041  -13.59888 -44.26691 1.000 33.19458  ?  84  GLU A OE1 1 
ATOM   457  O  OE2 . GLU A 1 84  ? 23.82489  -11.72333 -43.90438 1.000 41.28797  -1 84  GLU A OE2 1 
ATOM   458  N  N   . TYR A 1 85  ? 27.61871  -15.40440 -43.40633 1.000 19.34588  ?  85  TYR A N   1 
ATOM   459  C  CA  . TYR A 1 85  ? 28.12563  -15.61793 -42.05106 1.000 17.99927  ?  85  TYR A CA  1 
ATOM   460  C  C   . TYR A 1 85  ? 27.26496  -14.79743 -41.09934 1.000 16.94649  ?  85  TYR A C   1 
ATOM   461  O  O   . TYR A 1 85  ? 27.48741  -13.59777 -40.91736 1.000 19.19101  ?  85  TYR A O   1 
ATOM   462  C  CB  . TYR A 1 85  ? 29.59663  -15.22951 -41.95773 1.000 16.58046  ?  85  TYR A CB  1 
ATOM   463  C  CG  . TYR A 1 85  ? 30.25139  -15.55395 -40.63236 1.000 13.68365  ?  85  TYR A CG  1 
ATOM   464  C  CD1 . TYR A 1 85  ? 30.50181  -16.86814 -40.26235 1.000 14.44978  ?  85  TYR A CD1 1 
ATOM   465  C  CD2 . TYR A 1 85  ? 30.63770  -14.54443 -39.76063 1.000 15.11270  ?  85  TYR A CD2 1 
ATOM   466  C  CE1 . TYR A 1 85  ? 31.10881  -17.16805 -39.05746 1.000 15.29295  ?  85  TYR A CE1 1 
ATOM   467  C  CE2 . TYR A 1 85  ? 31.24637  -14.83507 -38.55369 1.000 12.61045  ?  85  TYR A CE2 1 
ATOM   468  C  CZ  . TYR A 1 85  ? 31.47816  -16.14830 -38.20741 1.000 11.05126  ?  85  TYR A CZ  1 
ATOM   469  O  OH  . TYR A 1 85  ? 32.08212  -16.44604 -37.00813 1.000 9.95656   ?  85  TYR A OH  1 
ATOM   470  N  N   . MET A 1 86  ? 26.27734  -15.45274 -40.49181 1.000 17.91353  ?  86  MET A N   1 
ATOM   471  C  CA  . MET A 1 86  ? 25.32051  -14.74701 -39.64243 1.000 21.05961  ?  86  MET A CA  1 
ATOM   472  C  C   . MET A 1 86  ? 25.94287  -13.97463 -38.48207 1.000 22.60760  ?  86  MET A C   1 
ATOM   473  O  O   . MET A 1 86  ? 25.44694  -12.87309 -38.18752 1.000 22.72344  ?  86  MET A O   1 
ATOM   474  C  CB  . MET A 1 86  ? 24.26608  -15.73367 -39.12727 1.000 21.22061  ?  86  MET A CB  1 
ATOM   475  C  CG  . MET A 1 86  ? 23.33103  -16.23165 -40.21171 1.000 30.14102  ?  86  MET A CG  1 
ATOM   476  S  SD  . MET A 1 86  ? 22.74051  -14.87816 -41.24822 1.000 22.92902  ?  86  MET A SD  1 
ATOM   477  C  CE  . MET A 1 86  ? 21.83155  -13.89651 -40.05521 1.000 33.14019  ?  86  MET A CE  1 
ATOM   478  N  N   . PRO A 1 87  ? 26.97087  -14.46723 -37.77683 1.000 21.06538  ?  87  PRO A N   1 
ATOM   479  C  CA  . PRO A 1 87  ? 27.49783  -13.68611 -36.64339 1.000 15.27724  ?  87  PRO A CA  1 
ATOM   480  C  C   . PRO A 1 87  ? 27.94740  -12.28122 -37.01231 1.000 15.99234  ?  87  PRO A C   1 
ATOM   481  O  O   . PRO A 1 87  ? 27.85789  -11.37658 -36.17332 1.000 17.28297  ?  87  PRO A O   1 
ATOM   482  C  CB  . PRO A 1 87  ? 28.67163  -14.54127 -36.15266 1.000 14.06667  ?  87  PRO A CB  1 
ATOM   483  C  CG  . PRO A 1 87  ? 28.29203  -15.92384 -36.51550 1.000 10.97693  ?  87  PRO A CG  1 
ATOM   484  C  CD  . PRO A 1 87  ? 27.58617  -15.80849 -37.83289 1.000 13.23158  ?  87  PRO A CD  1 
ATOM   485  N  N   . ALA A 1 88  ? 28.42374  -12.06449 -38.23495 1.000 16.96008  ?  88  ALA A N   1 
ATOM   486  C  CA  . ALA A 1 88  ? 28.86215  -10.74387 -38.66542 1.000 14.12852  ?  88  ALA A CA  1 
ATOM   487  C  C   . ALA A 1 88  ? 27.75305  -9.92738  -39.31506 1.000 17.05314  ?  88  ALA A C   1 
ATOM   488  O  O   . ALA A 1 88  ? 27.99639  -8.78057  -39.70501 1.000 20.54525  ?  88  ALA A O   1 
ATOM   489  C  CB  . ALA A 1 88  ? 30.03766  -10.86781 -39.63686 1.000 16.72813  ?  88  ALA A CB  1 
ATOM   490  N  N   . ALA A 1 89  ? 26.55085  -10.48243 -39.44268 1.000 17.23565  ?  89  ALA A N   1 
ATOM   491  C  CA  . ALA A 1 89  ? 25.44223  -9.76978  -40.05541 1.000 14.24752  ?  89  ALA A CA  1 
ATOM   492  C  C   . ALA A 1 89  ? 24.88831  -8.72462  -39.08943 1.000 13.73089  ?  89  ALA A C   1 
ATOM   493  O  O   . ALA A 1 89  ? 25.35907  -8.56950  -37.95860 1.000 13.92796  ?  89  ALA A O   1 
ATOM   494  C  CB  . ALA A 1 89  ? 24.35514  -10.74974 -40.48677 1.000 12.21034  ?  89  ALA A CB  1 
ATOM   495  N  N   . SER A 1 90  ? 23.87612  -7.98970  -39.54733 1.000 13.31832  ?  90  SER A N   1 
ATOM   496  C  CA  . SER A 1 90  ? 23.20728  -7.02063  -38.68977 1.000 11.77238  ?  90  SER A CA  1 
ATOM   497  C  C   . SER A 1 90  ? 22.61824  -7.71533  -37.46997 1.000 14.00603  ?  90  SER A C   1 
ATOM   498  O  O   . SER A 1 90  ? 22.06723  -8.81443  -37.56986 1.000 19.55581  ?  90  SER A O   1 
ATOM   499  C  CB  . SER A 1 90  ? 22.10500  -6.29927  -39.46414 1.000 14.26957  ?  90  SER A CB  1 
ATOM   500  O  OG  . SER A 1 90  ? 21.28100  -5.54956  -38.58920 1.000 18.22046  ?  90  SER A OG  1 
ATOM   501  N  N   . PHE A 1 91  ? 22.74097  -7.06745  -36.30814 1.000 12.71814  ?  91  PHE A N   1 
ATOM   502  C  CA  . PHE A 1 91  ? 22.25071  -7.67749  -35.07602 1.000 17.31918  ?  91  PHE A CA  1 
ATOM   503  C  C   . PHE A 1 91  ? 20.75068  -7.93685  -35.13446 1.000 19.22918  ?  91  PHE A C   1 
ATOM   504  O  O   . PHE A 1 91  ? 20.26135  -8.87777  -34.50050 1.000 23.25431  ?  91  PHE A O   1 
ATOM   505  C  CB  . PHE A 1 91  ? 22.59352  -6.79853  -33.87320 1.000 19.10155  ?  91  PHE A CB  1 
ATOM   506  C  CG  . PHE A 1 91  ? 22.20003  -7.40133  -32.55371 1.000 26.16118  ?  91  PHE A CG  1 
ATOM   507  C  CD1 . PHE A 1 91  ? 22.93858  -8.43726  -32.00340 1.000 23.41113  ?  91  PHE A CD1 1 
ATOM   508  C  CD2 . PHE A 1 91  ? 21.09240  -6.93459  -31.86428 1.000 22.94530  ?  91  PHE A CD2 1 
ATOM   509  C  CE1 . PHE A 1 91  ? 22.58033  -8.99731  -30.79039 1.000 18.21025  ?  91  PHE A CE1 1 
ATOM   510  C  CE2 . PHE A 1 91  ? 20.72891  -7.49024  -30.65040 1.000 24.56161  ?  91  PHE A CE2 1 
ATOM   511  C  CZ  . PHE A 1 91  ? 21.47472  -8.52316  -30.11309 1.000 21.37962  ?  91  PHE A CZ  1 
ATOM   512  N  N   . TYR A 1 92  ? 20.01019  -7.12743  -35.89500 1.000 15.49727  ?  92  TYR A N   1 
ATOM   513  C  CA  . TYR A 1 92  ? 18.58570  -7.38210  -36.08517 1.000 12.82393  ?  92  TYR A CA  1 
ATOM   514  C  C   . TYR A 1 92  ? 18.35598  -8.75296  -36.70648 1.000 17.16475  ?  92  TYR A C   1 
ATOM   515  O  O   . TYR A 1 92  ? 17.54405  -9.54548  -36.21497 1.000 26.35756  ?  92  TYR A O   1 
ATOM   516  C  CB  . TYR A 1 92  ? 17.97708  -6.28468  -36.96059 1.000 18.21946  ?  92  TYR A CB  1 
ATOM   517  C  CG  . TYR A 1 92  ? 16.55386  -6.54594  -37.41287 1.000 21.37020  ?  92  TYR A CG  1 
ATOM   518  C  CD1 . TYR A 1 92  ? 15.47313  -6.13378  -36.64354 1.000 22.05166  ?  92  TYR A CD1 1 
ATOM   519  C  CD2 . TYR A 1 92  ? 16.29118  -7.18841  -38.61835 1.000 19.23622  ?  92  TYR A CD2 1 
ATOM   520  C  CE1 . TYR A 1 92  ? 14.17230  -6.36336  -37.05553 1.000 17.72920  ?  92  TYR A CE1 1 
ATOM   521  C  CE2 . TYR A 1 92  ? 14.99430  -7.42354  -39.03677 1.000 17.26962  ?  92  TYR A CE2 1 
ATOM   522  C  CZ  . TYR A 1 92  ? 13.93954  -7.00842  -38.25210 1.000 14.44383  ?  92  TYR A CZ  1 
ATOM   523  O  OH  . TYR A 1 92  ? 12.64757  -7.23821  -38.66529 1.000 10.95781  ?  92  TYR A OH  1 
ATOM   524  N  N   . ARG A 1 93  ? 19.07363  -9.05142  -37.78893 1.000 17.09005  ?  93  ARG A N   1 
ATOM   525  C  CA  . ARG A 1 93  ? 18.89592  -10.31833 -38.48650 1.000 23.17539  ?  93  ARG A CA  1 
ATOM   526  C  C   . ARG A 1 93  ? 19.55979  -11.47844 -37.75570 1.000 19.28584  ?  93  ARG A C   1 
ATOM   527  O  O   . ARG A 1 93  ? 19.07092  -12.61162 -37.82726 1.000 17.11730  ?  93  ARG A O   1 
ATOM   528  C  CB  . ARG A 1 93  ? 19.44634  -10.20052 -39.90852 1.000 22.65015  ?  93  ARG A CB  1 
ATOM   529  C  CG  . ARG A 1 93  ? 18.91157  -8.98875  -40.66048 1.000 23.63631  ?  93  ARG A CG  1 
ATOM   530  C  CD  . ARG A 1 93  ? 19.68574  -8.71233  -41.94138 1.000 28.33813  ?  93  ARG A CD  1 
ATOM   531  N  NE  . ARG A 1 93  ? 19.63316  -9.83183  -42.87344 1.000 37.18080  ?  93  ARG A NE  1 
ATOM   532  C  CZ  . ARG A 1 93  ? 20.64876  -10.64690 -43.12136 1.000 33.96687  ?  93  ARG A CZ  1 
ATOM   533  N  NH1 . ARG A 1 93  ? 21.82316  -10.48400 -42.53590 1.000 37.13301  ?  93  ARG A NH1 1 
ATOM   534  N  NH2 . ARG A 1 93  ? 20.48305  -11.64740 -43.98172 1.000 31.92025  ?  93  ARG A NH2 1 
ATOM   535  N  N   . SER A 1 94  ? 20.65829  -11.22127 -37.05201 1.000 18.04758  ?  94  SER A N   1 
ATOM   536  C  CA  . SER A 1 94  ? 21.43967  -12.27441 -36.42103 1.000 20.53343  ?  94  SER A CA  1 
ATOM   537  C  C   . SER A 1 94  ? 21.05157  -12.54031 -34.97242 1.000 23.37974  ?  94  SER A C   1 
ATOM   538  O  O   . SER A 1 94  ? 21.60276  -13.46404 -34.37020 1.000 25.79285  ?  94  SER A O   1 
ATOM   539  C  CB  . SER A 1 94  ? 22.93195  -11.93122 -36.48160 1.000 15.77336  ?  94  SER A CB  1 
ATOM   540  O  OG  . SER A 1 94  ? 23.26128  -10.92353 -35.54092 1.000 12.87586  ?  94  SER A OG  1 
ATOM   541  N  N   . LYS A 1 95  ? 20.13184  -11.76426 -34.39348 1.000 18.87298  ?  95  LYS A N   1 
ATOM   542  C  CA  . LYS A 1 95  ? 19.84527  -11.91148 -32.96892 1.000 17.94729  ?  95  LYS A CA  1 
ATOM   543  C  C   . LYS A 1 95  ? 19.22827  -13.27068 -32.66031 1.000 16.86323  ?  95  LYS A C   1 
ATOM   544  O  O   . LYS A 1 95  ? 19.67098  -13.96917 -31.74176 1.000 18.67250  ?  95  LYS A O   1 
ATOM   545  C  CB  . LYS A 1 95  ? 18.92798  -10.78566 -32.49460 1.000 17.11477  ?  95  LYS A CB  1 
ATOM   546  C  CG  . LYS A 1 95  ? 18.63167  -10.83862 -31.00610 1.000 15.46790  ?  95  LYS A CG  1 
ATOM   547  C  CD  . LYS A 1 95  ? 17.54819  -9.85185  -30.62109 1.000 16.34426  ?  95  LYS A CD  1 
ATOM   548  C  CE  . LYS A 1 95  ? 17.11345  -10.04984 -29.18031 1.000 13.74928  ?  95  LYS A CE  1 
ATOM   549  N  NZ  . LYS A 1 95  ? 15.96635  -9.16845  -28.83255 1.000 15.68953  ?  95  LYS A NZ  1 
ATOM   550  N  N   . ASP A 1 96  ? 18.20254  -13.66433 -33.41689 1.000 17.94045  ?  96  ASP A N   1 
ATOM   551  C  CA  . ASP A 1 96  ? 17.57377  -14.96057 -33.18278 1.000 18.33315  ?  96  ASP A CA  1 
ATOM   552  C  C   . ASP A 1 96  ? 18.54737  -16.09968 -33.46184 1.000 22.62568  ?  96  ASP A C   1 
ATOM   553  O  O   . ASP A 1 96  ? 18.60333  -17.08448 -32.70929 1.000 24.29417  ?  96  ASP A O   1 
ATOM   554  C  CB  . ASP A 1 96  ? 16.31876  -15.09164 -34.04513 1.000 23.90981  ?  96  ASP A CB  1 
ATOM   555  C  CG  . ASP A 1 96  ? 15.35941  -13.93015 -33.85647 1.000 24.21316  ?  96  ASP A CG  1 
ATOM   556  O  OD1 . ASP A 1 96  ? 15.31039  -13.37541 -32.73755 1.000 19.96530  ?  96  ASP A OD1 1 
ATOM   557  O  OD2 . ASP A 1 96  ? 14.65764  -13.57031 -34.82648 1.000 22.10346  -1 96  ASP A OD2 1 
ATOM   558  N  N   . PHE A 1 97  ? 19.33293  -15.97443 -34.53490 1.000 18.48726  ?  97  PHE A N   1 
ATOM   559  C  CA  . PHE A 1 97  ? 20.34153  -16.98205 -34.84086 1.000 18.11885  ?  97  PHE A CA  1 
ATOM   560  C  C   . PHE A 1 97  ? 21.30532  -17.15554 -33.67507 1.000 26.19211  ?  97  PHE A C   1 
ATOM   561  O  O   . PHE A 1 97  ? 21.62291  -18.28200 -33.28099 1.000 33.38333  ?  97  PHE A O   1 
ATOM   562  C  CB  . PHE A 1 97  ? 21.09679  -16.59806 -36.11369 1.000 16.53983  ?  97  PHE A CB  1 
ATOM   563  C  CG  . PHE A 1 97  ? 22.34348  -17.40467 -36.34468 1.000 21.60656  ?  97  PHE A CG  1 
ATOM   564  C  CD1 . PHE A 1 97  ? 22.28376  -18.62554 -36.99533 1.000 23.45139  ?  97  PHE A CD1 1 
ATOM   565  C  CD2 . PHE A 1 97  ? 23.57664  -16.94077 -35.91167 1.000 21.10971  ?  97  PHE A CD2 1 
ATOM   566  C  CE1 . PHE A 1 97  ? 23.42899  -19.36940 -37.20845 1.000 24.77798  ?  97  PHE A CE1 1 
ATOM   567  C  CE2 . PHE A 1 97  ? 24.72348  -17.68003 -36.11933 1.000 20.49572  ?  97  PHE A CE2 1 
ATOM   568  C  CZ  . PHE A 1 97  ? 24.65017  -18.89576 -36.76980 1.000 25.41971  ?  97  PHE A CZ  1 
ATOM   569  N  N   . ILE A 1 98  ? 21.77426  -16.04373 -33.10446 1.000 22.54357  ?  98  ILE A N   1 
ATOM   570  C  CA  . ILE A 1 98  ? 22.64494  -16.10946 -31.93429 1.000 20.50448  ?  98  ILE A CA  1 
ATOM   571  C  C   . ILE A 1 98  ? 21.91963  -16.77515 -30.77378 1.000 20.36593  ?  98  ILE A C   1 
ATOM   572  O  O   . ILE A 1 98  ? 22.49549  -17.59345 -30.04575 1.000 21.19864  ?  98  ILE A O   1 
ATOM   573  C  CB  . ILE A 1 98  ? 23.13942  -14.69917 -31.56136 1.000 24.78426  ?  98  ILE A CB  1 
ATOM   574  C  CG1 . ILE A 1 98  ? 24.04634  -14.14366 -32.66075 1.000 22.35060  ?  98  ILE A CG1 1 
ATOM   575  C  CG2 . ILE A 1 98  ? 23.86209  -14.71721 -30.22255 1.000 27.99725  ?  98  ILE A CG2 1 
ATOM   576  C  CD1 . ILE A 1 98  ? 24.37531  -12.67774 -32.50023 1.000 20.87329  ?  98  ILE A CD1 1 
ATOM   577  N  N   . ASP A 1 99  ? 20.64030  -16.44418 -30.59141 1.000 21.00136  ?  99  ASP A N   1 
ATOM   578  C  CA  . ASP A 1 99  ? 19.84176  -17.04010 -29.52869 1.000 22.01038  ?  99  ASP A CA  1 
ATOM   579  C  C   . ASP A 1 99  ? 19.61391  -18.53371 -29.72329 1.000 20.94402  ?  99  ASP A C   1 
ATOM   580  O  O   . ASP A 1 99  ? 19.16730  -19.19584 -28.78112 1.000 21.23857  ?  99  ASP A O   1 
ATOM   581  C  CB  . ASP A 1 99  ? 18.49362  -16.32303 -29.41673 1.000 22.56631  ?  99  ASP A CB  1 
ATOM   582  C  CG  . ASP A 1 99  ? 18.63792  -14.86328 -29.02470 1.000 20.64022  ?  99  ASP A CG  1 
ATOM   583  O  OD1 . ASP A 1 99  ? 19.60471  -14.52765 -28.30846 1.000 17.24583  ?  99  ASP A OD1 1 
ATOM   584  O  OD2 . ASP A 1 99  ? 17.78289  -14.05019 -29.43445 1.000 25.67522  -1 99  ASP A OD2 1 
ATOM   585  N  N   . THR A 1 100 ? 19.89160  -19.07826 -30.90898 1.000 21.90760  ?  100 THR A N   1 
ATOM   586  C  CA  . THR A 1 100 ? 19.74012  -20.51068 -31.14529 1.000 18.75450  ?  100 THR A CA  1 
ATOM   587  C  C   . THR A 1 100 ? 21.06675  -21.27356 -31.18769 1.000 17.53825  ?  100 THR A C   1 
ATOM   588  O  O   . THR A 1 100 ? 21.08330  -22.42684 -31.62897 1.000 21.41898  ?  100 THR A O   1 
ATOM   589  C  CB  . THR A 1 100 ? 18.96413  -20.75976 -32.44292 1.000 16.45145  ?  100 THR A CB  1 
ATOM   590  O  OG1 . THR A 1 100 ? 19.68665  -20.21814 -33.55536 1.000 12.25077  ?  100 THR A OG1 1 
ATOM   591  C  CG2 . THR A 1 100 ? 17.58490  -20.12078 -32.37301 1.000 24.63784  ?  100 THR A CG2 1 
ATOM   592  N  N   . THR A 1 101 ? 22.17128  -20.67322 -30.74409 1.000 20.31861  ?  101 THR A N   1 
ATOM   593  C  CA  . THR A 1 101 ? 23.47360  -21.33308 -30.76018 1.000 21.44937  ?  101 THR A CA  1 
ATOM   594  C  C   . THR A 1 101 ? 23.87087  -21.79002 -29.36052 1.000 23.88182  ?  101 THR A C   1 
ATOM   595  O  O   . THR A 1 101 ? 23.62995  -21.08945 -28.37511 1.000 28.35916  ?  101 THR A O   1 
ATOM   596  C  CB  . THR A 1 101 ? 24.56573  -20.41083 -31.31183 1.000 20.73539  ?  101 THR A CB  1 
ATOM   597  O  OG1 . THR A 1 101 ? 24.81041  -19.34448 -30.38671 1.000 25.61520  ?  101 THR A OG1 1 
ATOM   598  C  CG2 . THR A 1 101 ? 24.16199  -19.82933 -32.65073 1.000 18.16583  ?  101 THR A CG2 1 
ATOM   599  N  N   . PHE A 1 102 ? 24.51282  -22.95932 -29.28538 1.000 20.25262  ?  102 PHE A N   1 
ATOM   600  C  CA  . PHE A 1 102 ? 24.95599  -23.48754 -27.99595 1.000 24.96770  ?  102 PHE A CA  1 
ATOM   601  C  C   . PHE A 1 102 ? 26.01036  -22.58814 -27.35477 1.000 27.79003  ?  102 PHE A C   1 
ATOM   602  O  O   . PHE A 1 102 ? 26.02106  -22.39960 -26.12820 1.000 32.88552  ?  102 PHE A O   1 
ATOM   603  C  CB  . PHE A 1 102 ? 25.50502  -24.90639 -28.16883 1.000 32.13429  ?  102 PHE A CB  1 
ATOM   604  C  CG  . PHE A 1 102 ? 24.57778  -25.83922 -28.90391 1.000 35.93422  ?  102 PHE A CG  1 
ATOM   605  C  CD1 . PHE A 1 102 ? 23.55666  -26.49256 -28.23439 1.000 38.60479  ?  102 PHE A CD1 1 
ATOM   606  C  CD2 . PHE A 1 102 ? 24.73821  -26.07431 -30.26104 1.000 33.51476  ?  102 PHE A CD2 1 
ATOM   607  C  CE1 . PHE A 1 102 ? 22.70537  -27.35246 -28.90521 1.000 30.90855  ?  102 PHE A CE1 1 
ATOM   608  C  CE2 . PHE A 1 102 ? 23.88953  -26.93394 -30.93741 1.000 25.03686  ?  102 PHE A CE2 1 
ATOM   609  C  CZ  . PHE A 1 102 ? 22.87247  -27.57307 -30.25764 1.000 28.23273  ?  102 PHE A CZ  1 
ATOM   610  N  N   . ALA A 1 103 ? 26.91618  -22.03537 -28.16804 1.000 21.37477  ?  103 ALA A N   1 
ATOM   611  C  CA  . ALA A 1 103 ? 27.98400  -21.19853 -27.63055 1.000 18.68336  ?  103 ALA A CA  1 
ATOM   612  C  C   . ALA A 1 103 ? 27.43358  -19.95734 -26.94147 1.000 26.32681  ?  103 ALA A C   1 
ATOM   613  O  O   . ALA A 1 103 ? 28.01776  -19.48122 -25.96021 1.000 36.13038  ?  103 ALA A O   1 
ATOM   614  C  CB  . ALA A 1 103 ? 28.95619  -20.80561 -28.74271 1.000 18.94207  ?  103 ALA A CB  1 
ATOM   615  N  N   . TYR A 1 104 ? 26.31389  -19.41877 -27.42944 1.000 22.63077  ?  104 TYR A N   1 
ATOM   616  C  CA  . TYR A 1 104 ? 25.70535  -18.29186 -26.73423 1.000 20.42625  ?  104 TYR A CA  1 
ATOM   617  C  C   . TYR A 1 104 ? 25.17573  -18.69941 -25.36649 1.000 19.48592  ?  104 TYR A C   1 
ATOM   618  O  O   . TYR A 1 104 ? 25.22966  -17.90188 -24.42867 1.000 23.00657  ?  104 TYR A O   1 
ATOM   619  C  CB  . TYR A 1 104 ? 24.58741  -17.67101 -27.56856 1.000 23.91114  ?  104 TYR A CB  1 
ATOM   620  C  CG  . TYR A 1 104 ? 23.91255  -16.51957 -26.85901 1.000 23.10241  ?  104 TYR A CG  1 
ATOM   621  C  CD1 . TYR A 1 104 ? 24.65126  -15.43420 -26.40411 1.000 23.74986  ?  104 TYR A CD1 1 
ATOM   622  C  CD2 . TYR A 1 104 ? 22.54337  -16.52023 -26.63354 1.000 18.76341  ?  104 TYR A CD2 1 
ATOM   623  C  CE1 . TYR A 1 104 ? 24.04497  -14.38132 -25.74741 1.000 21.36105  ?  104 TYR A CE1 1 
ATOM   624  C  CE2 . TYR A 1 104 ? 21.92766  -15.46909 -25.97979 1.000 17.11781  ?  104 TYR A CE2 1 
ATOM   625  C  CZ  . TYR A 1 104 ? 22.68337  -14.40338 -25.53764 1.000 15.52770  ?  104 TYR A CZ  1 
ATOM   626  O  OH  . TYR A 1 104 ? 22.07715  -13.35454 -24.88504 1.000 11.32520  ?  104 TYR A OH  1 
ATOM   627  N  N   . LYS A 1 105 ? 24.66044  -19.92454 -25.22922 1.000 26.32738  ?  105 LYS A N   1 
ATOM   628  C  CA  . LYS A 1 105 ? 24.28375  -20.41855 -23.90657 1.000 27.93002  ?  105 LYS A CA  1 
ATOM   629  C  C   . LYS A 1 105 ? 25.50254  -20.52108 -22.99952 1.000 22.52908  ?  105 LYS A C   1 
ATOM   630  O  O   . LYS A 1 105 ? 25.44528  -20.15048 -21.81740 1.000 19.71183  ?  105 LYS A O   1 
ATOM   631  C  CB  . LYS A 1 105 ? 23.58780  -21.77648 -24.02813 1.000 32.07552  ?  105 LYS A CB  1 
ATOM   632  C  CG  . LYS A 1 105 ? 22.79490  -22.20043 -22.79429 1.000 31.58497  ?  105 LYS A CG  1 
ATOM   633  C  CD  . LYS A 1 105 ? 23.59583  -23.10802 -21.87391 1.000 31.94550  ?  105 LYS A CD  1 
ATOM   634  C  CE  . LYS A 1 105 ? 22.75521  -23.56901 -20.69174 1.000 32.16978  ?  105 LYS A CE  1 
ATOM   635  N  NZ  . LYS A 1 105 ? 22.31752  -22.43582 -19.83122 1.000 30.20664  ?  105 LYS A NZ  1 
ATOM   636  N  N   . ILE A 1 106 ? 26.61844  -21.01771 -23.54198 1.000 28.12624  ?  106 ILE A N   1 
ATOM   637  C  CA  . ILE A 1 106 ? 27.85263  -21.09661 -22.76174 1.000 29.93202  ?  106 ILE A CA  1 
ATOM   638  C  C   . ILE A 1 106 ? 28.26293  -19.71217 -22.27277 1.000 29.83418  ?  106 ILE A C   1 
ATOM   639  O  O   . ILE A 1 106 ? 28.64500  -19.53364 -21.10936 1.000 28.22563  ?  106 ILE A O   1 
ATOM   640  C  CB  . ILE A 1 106 ? 28.97062  -21.75562 -23.59191 1.000 25.30036  ?  106 ILE A CB  1 
ATOM   641  C  CG1 . ILE A 1 106 ? 28.56615  -23.16968 -24.01212 1.000 28.94190  ?  106 ILE A CG1 1 
ATOM   642  C  CG2 . ILE A 1 106 ? 30.27532  -21.78324 -22.80818 1.000 20.38872  ?  106 ILE A CG2 1 
ATOM   643  C  CD1 . ILE A 1 106 ? 28.42387  -24.13524 -22.85805 1.000 33.88834  ?  106 ILE A CD1 1 
ATOM   644  N  N   . ILE A 1 107 ? 28.18625  -18.71194 -23.15234 1.000 29.40496  ?  107 ILE A N   1 
ATOM   645  C  CA  . ILE A 1 107 ? 28.56393  -17.35220 -22.77404 1.000 23.71934  ?  107 ILE A CA  1 
ATOM   646  C  C   . ILE A 1 107 ? 27.57254  -16.77383 -21.76741 1.000 23.54723  ?  107 ILE A C   1 
ATOM   647  O  O   . ILE A 1 107 ? 27.95913  -16.04225 -20.84746 1.000 26.95512  ?  107 ILE A O   1 
ATOM   648  C  CB  . ILE A 1 107 ? 28.69171  -16.46979 -24.02859 1.000 20.87508  ?  107 ILE A CB  1 
ATOM   649  C  CG1 . ILE A 1 107 ? 29.78874  -17.01707 -24.94165 1.000 14.94819  ?  107 ILE A CG1 1 
ATOM   650  C  CG2 . ILE A 1 107 ? 28.99675  -15.02973 -23.64705 1.000 27.99170  ?  107 ILE A CG2 1 
ATOM   651  C  CD1 . ILE A 1 107 ? 29.97680  -16.22696 -26.20968 1.000 17.27323  ?  107 ILE A CD1 1 
ATOM   652  N  N   . GLN A 1 108 ? 26.28293  -17.08536 -21.92632 1.000 20.04721  ?  108 GLN A N   1 
ATOM   653  C  CA  . GLN A 1 108 ? 25.27719  -16.64616 -20.96388 1.000 15.59316  ?  108 GLN A CA  1 
ATOM   654  C  C   . GLN A 1 108 ? 25.60643  -17.14776 -19.56639 1.000 22.61696  ?  108 GLN A C   1 
ATOM   655  O  O   . GLN A 1 108 ? 25.58675  -16.38081 -18.59720 1.000 25.17179  ?  108 GLN A O   1 
ATOM   656  C  CB  . GLN A 1 108 ? 23.89228  -17.13977 -21.38410 1.000 18.39749  ?  108 GLN A CB  1 
ATOM   657  C  CG  . GLN A 1 108 ? 23.16245  -16.26507 -22.38460 1.000 21.61219  ?  108 GLN A CG  1 
ATOM   658  C  CD  . GLN A 1 108 ? 21.75036  -16.75959 -22.65064 1.000 23.89262  ?  108 GLN A CD  1 
ATOM   659  O  OE1 . GLN A 1 108 ? 21.46115  -17.94921 -22.51553 1.000 20.66874  ?  108 GLN A OE1 1 
ATOM   660  N  NE2 . GLN A 1 108 ? 20.86128  -15.84494 -23.01885 1.000 30.06757  ?  108 GLN A NE2 1 
ATOM   661  N  N   . ASP A 1 109 ? 25.91567  -18.44110 -19.44419 1.000 26.42245  ?  109 ASP A N   1 
ATOM   662  C  CA  . ASP A 1 109 ? 26.28807  -18.98744 -18.14392 1.000 23.67314  ?  109 ASP A CA  1 
ATOM   663  C  C   . ASP A 1 109 ? 27.63223  -18.45928 -17.65712 1.000 24.36872  ?  109 ASP A C   1 
ATOM   664  O  O   . ASP A 1 109 ? 27.91252  -18.52642 -16.45547 1.000 26.20521  ?  109 ASP A O   1 
ATOM   665  C  CB  . ASP A 1 109 ? 26.32217  -20.51562 -18.20320 1.000 25.03879  ?  109 ASP A CB  1 
ATOM   666  C  CG  . ASP A 1 109 ? 24.95406  -21.12211 -18.44450 1.000 30.68954  ?  109 ASP A CG  1 
ATOM   667  O  OD1 . ASP A 1 109 ? 23.96383  -20.36289 -18.49984 1.000 36.00900  ?  109 ASP A OD1 1 
ATOM   668  O  OD2 . ASP A 1 109 ? 24.86885  -22.36099 -18.57709 1.000 32.76153  -1 109 ASP A OD2 1 
ATOM   669  N  N   . MET A 1 110 ? 28.45583  -17.93221 -18.55524 1.000 21.01755  ?  110 MET A N   1 
ATOM   670  C  CA  . MET A 1 110 ? 29.80365  -17.49431 -18.21185 1.000 19.21948  ?  110 MET A CA  1 
ATOM   671  C  C   . MET A 1 110 ? 29.76240  -16.17333 -17.45056 1.000 21.23858  ?  110 MET A C   1 
ATOM   672  O  O   . MET A 1 110 ? 29.11466  -15.22510 -17.90355 1.000 27.88119  ?  110 MET A O   1 
ATOM   673  C  CB  . MET A 1 110 ? 30.64429  -17.33655 -19.47368 1.000 22.75300  ?  110 MET A CB  1 
ATOM   674  C  CG  . MET A 1 110 ? 32.00317  -16.71057 -19.23569 1.000 22.91392  ?  110 MET A CG  1 
ATOM   675  S  SD  . MET A 1 110 ? 32.94561  -16.49998 -20.75717 1.000 28.27624  ?  110 MET A SD  1 
ATOM   676  C  CE  . MET A 1 110 ? 32.84593  -18.14822 -21.44961 1.000 17.88098  ?  110 MET A CE  1 
ATOM   677  N  N   . PRO A 1 111 ? 30.42773  -16.07504 -16.29394 1.000 23.58180  ?  111 PRO A N   1 
ATOM   678  C  CA  . PRO A 1 111 ? 30.60551  -14.77538 -15.63038 1.000 26.49806  ?  111 PRO A CA  1 
ATOM   679  C  C   . PRO A 1 111 ? 31.68701  -13.96188 -16.32428 1.000 26.06341  ?  111 PRO A C   1 
ATOM   680  O  O   . PRO A 1 111 ? 32.86772  -14.32423 -16.31115 1.000 21.26521  ?  111 PRO A O   1 
ATOM   681  C  CB  . PRO A 1 111 ? 31.00570  -15.16828 -14.20104 1.000 25.89577  ?  111 PRO A CB  1 
ATOM   682  C  CG  . PRO A 1 111 ? 31.63982  -16.49760 -14.34650 1.000 22.77938  ?  111 PRO A CG  1 
ATOM   683  C  CD  . PRO A 1 111 ? 30.93545  -17.18977 -15.47707 1.000 21.04851  ?  111 PRO A CD  1 
ATOM   684  N  N   . LYS A 1 112 ? 31.28054  -12.85381 -16.93976 1.000 23.64126  ?  112 LYS A N   1 
ATOM   685  C  CA  . LYS A 1 112 ? 32.15523  -12.06023 -17.79160 1.000 19.05995  ?  112 LYS A CA  1 
ATOM   686  C  C   . LYS A 1 112 ? 32.80202  -10.88927 -17.06589 1.000 22.19124  ?  112 LYS A C   1 
ATOM   687  O  O   . LYS A 1 112 ? 33.50311  -10.09556 -17.70136 1.000 23.12519  ?  112 LYS A O   1 
ATOM   688  C  CB  . LYS A 1 112 ? 31.37689  -11.55695 -19.00924 1.000 16.75821  ?  112 LYS A CB  1 
ATOM   689  C  CG  . LYS A 1 112 ? 30.91626  -12.67401 -19.93465 1.000 19.83031  ?  112 LYS A CG  1 
ATOM   690  C  CD  . LYS A 1 112 ? 29.76867  -12.22881 -20.81658 1.000 20.68826  ?  112 LYS A CD  1 
ATOM   691  C  CE  . LYS A 1 112 ? 28.60806  -11.74039 -19.97639 1.000 23.70321  ?  112 LYS A CE  1 
ATOM   692  N  NZ  . LYS A 1 112 ? 28.23949  -12.74818 -18.95376 1.000 17.28155  ?  112 LYS A NZ  1 
ATOM   693  N  N   . GLY A 1 113 ? 32.58592  -10.75894 -15.76880 1.000 23.02710  ?  113 GLY A N   1 
ATOM   694  C  CA  . GLY A 1 113 ? 33.27556  -9.73603  -14.98040 1.000 19.72422  ?  113 GLY A CA  1 
ATOM   695  C  C   . GLY A 1 113 ? 32.50026  -8.41654  -14.95134 1.000 24.32800  ?  113 GLY A C   1 
ATOM   696  O  O   . GLY A 1 113 ? 31.45425  -8.32471  -14.30661 1.000 27.36224  ?  113 GLY A O   1 
ATOM   697  N  N   . GLY A 1 114 ? 33.02357  -7.41388  -15.64749 1.000 24.31665  ?  114 GLY A N   1 
ATOM   698  C  CA  . GLY A 1 114 ? 32.49008  -6.07026  -15.56023 1.000 17.02881  ?  114 GLY A CA  1 
ATOM   699  C  C   . GLY A 1 114 ? 32.15812  -5.47981  -16.91420 1.000 15.36351  ?  114 GLY A C   1 
ATOM   700  O  O   . GLY A 1 114 ? 32.80488  -5.76614  -17.92139 1.000 13.02687  ?  114 GLY A O   1 
ATOM   701  N  N   . ALA A 1 115 ? 31.12276  -4.64299  -16.91988 1.000 22.24543  ?  115 ALA A N   1 
ATOM   702  C  CA  . ALA A 1 115 ? 30.71951  -3.85961  -18.08562 1.000 21.34287  ?  115 ALA A CA  1 
ATOM   703  C  C   . ALA A 1 115 ? 31.06152  -2.40524  -17.78104 1.000 13.37886  ?  115 ALA A C   1 
ATOM   704  O  O   . ALA A 1 115 ? 30.31767  -1.71859  -17.07486 1.000 12.10970  ?  115 ALA A O   1 
ATOM   705  C  CB  . ALA A 1 115 ? 29.23415  -4.04045  -18.38411 1.000 16.31078  ?  115 ALA A CB  1 
ATOM   706  N  N   . LEU A 1 116 ? 32.18613  -1.93773  -18.31946 1.000 11.67223  ?  116 LEU A N   1 
ATOM   707  C  CA  . LEU A 1 116 ? 32.74956  -0.65370  -17.92613 1.000 15.10937  ?  116 LEU A CA  1 
ATOM   708  C  C   . LEU A 1 116 ? 32.21119  0.52766   -18.72392 1.000 16.83477  ?  116 LEU A C   1 
ATOM   709  O  O   . LEU A 1 116 ? 32.48913  1.67456   -18.35648 1.000 18.99014  ?  116 LEU A O   1 
ATOM   710  C  CB  . LEU A 1 116 ? 34.27700  -0.69265  -18.05153 1.000 12.86034  ?  116 LEU A CB  1 
ATOM   711  C  CG  . LEU A 1 116 ? 34.99947  -1.74121  -17.20244 1.000 17.26240  ?  116 LEU A CG  1 
ATOM   712  C  CD1 . LEU A 1 116 ? 36.50677  -1.64472  -17.39542 1.000 18.59400  ?  116 LEU A CD1 1 
ATOM   713  C  CD2 . LEU A 1 116 ? 34.63154  -1.59501  -15.73292 1.000 12.82827  ?  116 LEU A CD2 1 
ATOM   714  N  N   . HIS A 1 117 ? 31.44665  0.29197   -19.79016 1.000 14.08599  ?  117 HIS A N   1 
ATOM   715  C  CA  . HIS A 1 117 ? 30.96023  1.36768   -20.65753 1.000 15.06027  ?  117 HIS A CA  1 
ATOM   716  C  C   . HIS A 1 117 ? 29.44878  1.23170   -20.81934 1.000 21.54246  ?  117 HIS A C   1 
ATOM   717  O  O   . HIS A 1 117 ? 28.97002  0.56591   -21.74074 1.000 21.67620  ?  117 HIS A O   1 
ATOM   718  C  CB  . HIS A 1 117 ? 31.67003  1.34244   -22.00467 1.000 14.61135  ?  117 HIS A CB  1 
ATOM   719  C  CG  . HIS A 1 117 ? 31.37778  2.53399   -22.86058 1.000 15.24650  ?  117 HIS A CG  1 
ATOM   720  N  ND1 . HIS A 1 117 ? 32.32617  3.48979   -23.15190 1.000 15.75930  ?  117 HIS A ND1 1 
ATOM   721  C  CD2 . HIS A 1 117 ? 30.24140  2.92976   -23.48144 1.000 21.84929  ?  117 HIS A CD2 1 
ATOM   722  C  CE1 . HIS A 1 117 ? 31.78907  4.41973   -23.92078 1.000 23.37559  ?  117 HIS A CE1 1 
ATOM   723  N  NE2 . HIS A 1 117 ? 30.52379  4.10529   -24.13366 1.000 28.85807  ?  117 HIS A NE2 1 
ATOM   724  N  N   . LEU A 1 118 ? 28.69976  1.88322   -19.93302 1.000 26.49619  ?  118 LEU A N   1 
ATOM   725  C  CA  . LEU A 1 118 ? 27.24652  1.83618   -19.96085 1.000 21.70869  ?  118 LEU A CA  1 
ATOM   726  C  C   . LEU A 1 118 ? 26.69336  3.23861   -19.75522 1.000 23.39895  ?  118 LEU A C   1 
ATOM   727  O  O   . LEU A 1 118 ? 27.35548  4.11462   -19.19427 1.000 23.76268  ?  118 LEU A O   1 
ATOM   728  C  CB  . LEU A 1 118 ? 26.69178  0.88977   -18.88674 1.000 19.12666  ?  118 LEU A CB  1 
ATOM   729  C  CG  . LEU A 1 118 ? 27.18062  -0.55852  -18.92010 1.000 15.98222  ?  118 LEU A CG  1 
ATOM   730  C  CD1 . LEU A 1 118 ? 26.68883  -1.31217  -17.69747 1.000 17.90508  ?  118 LEU A CD1 1 
ATOM   731  C  CD2 . LEU A 1 118 ? 26.72768  -1.24499  -20.19516 1.000 14.02917  ?  118 LEU A CD2 1 
ATOM   732  N  N   . HIS A 1 119 ? 25.46655  3.44353   -20.22654 1.000 22.08027  ?  119 HIS A N   1 
ATOM   733  C  CA  . HIS A 1 119 ? 24.72206  4.67323   -19.99194 1.000 23.62136  ?  119 HIS A CA  1 
ATOM   734  C  C   . HIS A 1 119 ? 23.43562  4.32320   -19.25663 1.000 18.79414  ?  119 HIS A C   1 
ATOM   735  O  O   . HIS A 1 119 ? 22.72413  3.39361   -19.65097 1.000 25.91927  ?  119 HIS A O   1 
ATOM   736  C  CB  . HIS A 1 119 ? 24.42851  5.40344   -21.30654 1.000 26.68021  ?  119 HIS A CB  1 
ATOM   737  C  CG  . HIS A 1 119 ? 25.65994  5.81479   -22.05623 1.000 28.50420  ?  119 HIS A CG  1 
ATOM   738  N  ND1 . HIS A 1 119 ? 26.19569  7.08222   -21.97199 1.000 29.00846  ?  119 HIS A ND1 1 
ATOM   739  C  CD2 . HIS A 1 119 ? 26.46300  5.12359   -22.90029 1.000 26.30148  ?  119 HIS A CD2 1 
ATOM   740  C  CE1 . HIS A 1 119 ? 27.27304  7.15490   -22.73371 1.000 23.39105  ?  119 HIS A CE1 1 
ATOM   741  N  NE2 . HIS A 1 119 ? 27.45748  5.97971   -23.30851 1.000 23.78793  ?  119 HIS A NE2 1 
ATOM   742  N  N   . ASP A 1 120 ? 23.13876  5.07520   -18.19441 1.000 13.52089  ?  120 ASP A N   1 
ATOM   743  C  CA  . ASP A 1 120 ? 22.12964  4.66032   -17.22449 1.000 15.07544  ?  120 ASP A CA  1 
ATOM   744  C  C   . ASP A 1 120 ? 20.71235  4.63958   -17.78445 1.000 16.89514  ?  120 ASP A C   1 
ATOM   745  O  O   . ASP A 1 120 ? 19.87077  3.90172   -17.26304 1.000 17.18679  ?  120 ASP A O   1 
ATOM   746  C  CB  . ASP A 1 120 ? 22.18333  5.56717   -15.99056 1.000 15.30900  ?  120 ASP A CB  1 
ATOM   747  C  CG  . ASP A 1 120 ? 21.77623  6.99971   -16.28882 1.000 15.54383  ?  120 ASP A CG  1 
ATOM   748  O  OD1 . ASP A 1 120 ? 21.89735  7.44275   -17.44986 1.000 17.32613  ?  120 ASP A OD1 1 
ATOM   749  O  OD2 . ASP A 1 120 ? 21.34280  7.69240   -15.34566 1.000 15.97540  -1 120 ASP A OD2 1 
ATOM   750  N  N   . THR A 1 121 ? 20.41925  5.41983   -18.81899 1.000 15.04768  ?  121 THR A N   1 
ATOM   751  C  CA  . THR A 1 121 ? 19.04546  5.53702   -19.28764 1.000 15.93505  ?  121 THR A CA  1 
ATOM   752  C  C   . THR A 1 121 ? 18.65717  4.48275   -20.31638 1.000 23.18349  ?  121 THR A C   1 
ATOM   753  O  O   . THR A 1 121 ? 17.48257  4.41700   -20.69368 1.000 25.22021  ?  121 THR A O   1 
ATOM   754  C  CB  . THR A 1 121 ? 18.80148  6.93113   -19.87257 1.000 15.70976  ?  121 THR A CB  1 
ATOM   755  O  OG1 . THR A 1 121 ? 19.91800  7.31668   -20.68433 1.000 19.75332  ?  121 THR A OG1 1 
ATOM   756  C  CG2 . THR A 1 121 ? 18.61136  7.94464   -18.75824 1.000 19.71914  ?  121 THR A CG2 1 
ATOM   757  N  N   . ALA A 1 122 ? 19.59592  3.66662   -20.78837 1.000 19.91443  ?  122 ALA A N   1 
ATOM   758  C  CA  . ALA A 1 122 ? 19.26729  2.64090   -21.77151 1.000 19.48268  ?  122 ALA A CA  1 
ATOM   759  C  C   . ALA A 1 122 ? 20.01963  1.34822   -21.48536 1.000 25.65375  ?  122 ALA A C   1 
ATOM   760  O  O   . ALA A 1 122 ? 20.51545  0.68593   -22.40178 1.000 31.83112  ?  122 ALA A O   1 
ATOM   761  C  CB  . ALA A 1 122 ? 19.54795  3.13142   -23.19038 1.000 19.22907  ?  122 ALA A CB  1 
ATOM   762  N  N   . SER A 1 123 ? 20.11137  0.96388   -20.21072 1.000 20.94244  ?  123 SER A N   1 
ATOM   763  C  CA  . SER A 1 123 ? 20.80582  -0.25894  -19.82094 1.000 19.73920  ?  123 SER A CA  1 
ATOM   764  C  C   . SER A 1 123 ? 19.87850  -1.30676  -19.21565 1.000 19.97880  ?  123 SER A C   1 
ATOM   765  O  O   . SER A 1 123 ? 20.36298  -2.30127  -18.66231 1.000 24.60667  ?  123 SER A O   1 
ATOM   766  C  CB  . SER A 1 123 ? 21.94193  0.05964   -18.84441 1.000 20.52223  ?  123 SER A CB  1 
ATOM   767  O  OG  . SER A 1 123 ? 23.04780  0.62573   -19.52433 1.000 15.83907  ?  123 SER A OG  1 
ATOM   768  N  N   . ALA A 1 124 ? 18.56576  -1.11803  -19.30440 1.000 15.38987  ?  124 ALA A N   1 
ATOM   769  C  CA  . ALA A 1 124 ? 17.60434  -2.11069  -18.85256 1.000 15.95552  ?  124 ALA A CA  1 
ATOM   770  C  C   . ALA A 1 124 ? 16.56851  -2.32915  -19.94468 1.000 18.48974  ?  124 ALA A C   1 
ATOM   771  O  O   . ALA A 1 124 ? 16.43454  -1.52335  -20.86961 1.000 20.51043  ?  124 ALA A O   1 
ATOM   772  C  CB  . ALA A 1 124 ? 16.92124  -1.69294  -17.54410 1.000 19.48591  ?  124 ALA A CB  1 
ATOM   773  N  N   . ARG A 1 125 ? 15.84193  -3.43950  -19.83167 1.000 18.35572  ?  125 ARG A N   1 
ATOM   774  C  CA  . ARG A 1 125 ? 14.87218  -3.80336  -20.85604 1.000 25.29857  ?  125 ARG A CA  1 
ATOM   775  C  C   . ARG A 1 125 ? 13.80352  -2.72886  -21.00779 1.000 30.38710  ?  125 ARG A C   1 
ATOM   776  O  O   . ARG A 1 125 ? 13.28560  -2.19644  -20.02189 1.000 25.14992  ?  125 ARG A O   1 
ATOM   777  C  CB  . ARG A 1 125 ? 14.20789  -5.13817  -20.51774 1.000 25.42788  ?  125 ARG A CB  1 
ATOM   778  C  CG  . ARG A 1 125 ? 15.09891  -6.35774  -20.65881 1.000 25.32242  ?  125 ARG A CG  1 
ATOM   779  C  CD  . ARG A 1 125 ? 14.28752  -7.61702  -20.41403 1.000 25.54374  ?  125 ARG A CD  1 
ATOM   780  N  NE  . ARG A 1 125 ? 13.39162  -7.44658  -19.27651 1.000 39.48382  ?  125 ARG A NE  1 
ATOM   781  C  CZ  . ARG A 1 125 ? 13.69974  -7.76007  -18.02562 1.000 47.70230  ?  125 ARG A CZ  1 
ATOM   782  N  NH1 . ARG A 1 125 ? 14.86615  -8.30232  -17.71632 1.000 54.50548  ?  125 ARG A NH1 1 
ATOM   783  N  NH2 . ARG A 1 125 ? 12.81575  -7.52258  -17.06054 1.000 40.55063  ?  125 ARG A NH2 1 
ATOM   784  N  N   . ILE A 1 126 ? 13.47688  -2.41175  -22.26341 1.000 30.64626  ?  126 ILE A N   1 
ATOM   785  C  CA  . ILE A 1 126 ? 12.32242  -1.56454  -22.54275 1.000 22.96987  ?  126 ILE A CA  1 
ATOM   786  C  C   . ILE A 1 126 ? 11.05156  -2.23355  -22.04203 1.000 29.12582  ?  126 ILE A C   1 
ATOM   787  O  O   . ILE A 1 126 ? 10.08563  -1.55708  -21.66352 1.000 27.50583  ?  126 ILE A O   1 
ATOM   788  C  CB  . ILE A 1 126 ? 12.25017  -1.25323  -24.05130 1.000 14.59995  ?  126 ILE A CB  1 
ATOM   789  C  CG1 . ILE A 1 126 ? 13.53791  -0.57065  -24.51148 1.000 16.99458  ?  126 ILE A CG1 1 
ATOM   790  C  CG2 . ILE A 1 126 ? 11.04221  -0.38531  -24.37467 1.000 15.97929  ?  126 ILE A CG2 1 
ATOM   791  C  CD1 . ILE A 1 126 ? 13.55213  -0.22838  -25.97872 1.000 20.96696  ?  126 ILE A CD1 1 
ATOM   792  N  N   . ASP A 1 127 ? 11.03639  -3.56972  -22.02001 1.000 31.65457  ?  127 ASP A N   1 
ATOM   793  C  CA  . ASP A 1 127 ? 9.88320   -4.30299  -21.51258 1.000 26.27537  ?  127 ASP A CA  1 
ATOM   794  C  C   . ASP A 1 127 ? 9.58460   -3.95702  -20.06130 1.000 27.56577  ?  127 ASP A C   1 
ATOM   795  O  O   . ASP A 1 127 ? 8.41761   -3.95129  -19.65845 1.000 24.80711  ?  127 ASP A O   1 
ATOM   796  C  CB  . ASP A 1 127 ? 10.11416  -5.80556  -21.66261 1.000 28.98794  ?  127 ASP A CB  1 
ATOM   797  C  CG  . ASP A 1 127 ? 9.99082   -6.26896  -23.09611 1.000 39.51270  ?  127 ASP A CG  1 
ATOM   798  O  OD1 . ASP A 1 127 ? 8.96004   -5.95831  -23.72890 1.000 33.48865  ?  127 ASP A OD1 1 
ATOM   799  O  OD2 . ASP A 1 127 ? 10.92487  -6.93403  -23.59132 1.000 45.73857  -1 127 ASP A OD2 1 
ATOM   800  N  N   . TRP A 1 128 ? 10.61356  -3.67548  -19.25773 1.000 31.98789  ?  128 TRP A N   1 
ATOM   801  C  CA  . TRP A 1 128 ? 10.35507  -3.25497  -17.88466 1.000 27.53962  ?  128 TRP A CA  1 
ATOM   802  C  C   . TRP A 1 128 ? 9.66044   -1.90030  -17.84593 1.000 23.02746  ?  128 TRP A C   1 
ATOM   803  O  O   . TRP A 1 128 ? 8.75176   -1.68748  -17.03737 1.000 23.15661  ?  128 TRP A O   1 
ATOM   804  C  CB  . TRP A 1 128 ? 11.64841  -3.21048  -17.07405 1.000 24.40533  ?  128 TRP A CB  1 
ATOM   805  C  CG  . TRP A 1 128 ? 11.39885  -2.82036  -15.64854 1.000 26.09259  ?  128 TRP A CG  1 
ATOM   806  C  CD1 . TRP A 1 128 ? 11.07486  -3.65206  -14.61585 1.000 28.38984  ?  128 TRP A CD1 1 
ATOM   807  C  CD2 . TRP A 1 128 ? 11.42464  -1.49527  -15.10307 1.000 28.91027  ?  128 TRP A CD2 1 
ATOM   808  N  NE1 . TRP A 1 128 ? 10.90894  -2.92875  -13.45909 1.000 25.87081  ?  128 TRP A NE1 1 
ATOM   809  C  CE2 . TRP A 1 128 ? 11.11821  -1.60229  -13.73187 1.000 30.63788  ?  128 TRP A CE2 1 
ATOM   810  C  CE3 . TRP A 1 128 ? 11.68233  -0.22958  -15.64002 1.000 24.66379  ?  128 TRP A CE3 1 
ATOM   811  C  CZ2 . TRP A 1 128 ? 11.06287  -0.49324  -12.89154 1.000 30.23203  ?  128 TRP A CZ2 1 
ATOM   812  C  CZ3 . TRP A 1 128 ? 11.62725  0.87035   -14.80316 1.000 20.66107  ?  128 TRP A CZ3 1 
ATOM   813  C  CH2 . TRP A 1 128 ? 11.32028  0.73133   -13.44464 1.000 25.45872  ?  128 TRP A CH2 1 
ATOM   814  N  N   . ILE A 1 129 ? 10.07613  -0.96890  -18.70534 1.000 22.98280  ?  129 ILE A N   1 
ATOM   815  C  CA  . ILE A 1 129 ? 9.40176   0.32440   -18.76775 1.000 22.20523  ?  129 ILE A CA  1 
ATOM   816  C  C   . ILE A 1 129 ? 7.95312   0.14377   -19.20186 1.000 19.35696  ?  129 ILE A C   1 
ATOM   817  O  O   . ILE A 1 129 ? 7.04017   0.77304   -18.65351 1.000 19.27098  ?  129 ILE A O   1 
ATOM   818  C  CB  . ILE A 1 129 ? 10.16445  1.28306   -19.70276 1.000 21.80080  ?  129 ILE A CB  1 
ATOM   819  C  CG1 . ILE A 1 129 ? 11.49869  1.69395   -19.07339 1.000 15.25997  ?  129 ILE A CG1 1 
ATOM   820  C  CG2 . ILE A 1 129 ? 9.32111   2.50957   -20.02689 1.000 14.03731  ?  129 ILE A CG2 1 
ATOM   821  C  CD1 . ILE A 1 129 ? 12.26670  2.72001   -19.87816 1.000 9.93103   ?  129 ILE A CD1 1 
ATOM   822  N  N   . VAL A 1 130 ? 7.71834   -0.72947  -20.18201 1.000 19.02555  ?  130 VAL A N   1 
ATOM   823  C  CA  . VAL A 1 130 ? 6.37082   -0.90599  -20.71673 1.000 19.32656  ?  130 VAL A CA  1 
ATOM   824  C  C   . VAL A 1 130 ? 5.45879   -1.57042  -19.68871 1.000 19.81923  ?  130 VAL A C   1 
ATOM   825  O  O   . VAL A 1 130 ? 4.33324   -1.11822  -19.45261 1.000 25.50325  ?  130 VAL A O   1 
ATOM   826  C  CB  . VAL A 1 130 ? 6.41778   -1.70576  -22.03105 1.000 21.02453  ?  130 VAL A CB  1 
ATOM   827  C  CG1 . VAL A 1 130 ? 5.01172   -1.95685  -22.55070 1.000 20.16988  ?  130 VAL A CG1 1 
ATOM   828  C  CG2 . VAL A 1 130 ? 7.24693   -0.96659  -23.07076 1.000 22.95392  ?  130 VAL A CG2 1 
ATOM   829  N  N   . SER A 1 131 ? 5.92381   -2.64971  -19.06169 1.000 19.25568  ?  131 SER A N   1 
ATOM   830  C  CA  . SER A 1 131 ? 5.06989   -3.45040  -18.19248 1.000 19.68217  ?  131 SER A CA  1 
ATOM   831  C  C   . SER A 1 131 ? 5.05988   -2.98202  -16.74207 1.000 21.87275  ?  131 SER A C   1 
ATOM   832  O  O   . SER A 1 131 ? 4.20592   -3.43202  -15.97067 1.000 24.86664  ?  131 SER A O   1 
ATOM   833  C  CB  . SER A 1 131 ? 5.49642   -4.92219  -18.24508 1.000 18.03749  ?  131 SER A CB  1 
ATOM   834  O  OG  . SER A 1 131 ? 6.79354   -5.10022  -17.70468 1.000 23.63934  ?  131 SER A OG  1 
ATOM   835  N  N   . ASN A 1 132 ? 5.98256   -2.10899  -16.34744 1.000 25.28637  ?  132 ASN A N   1 
ATOM   836  C  CA  . ASN A 1 132 ? 6.04701   -1.60556  -14.98053 1.000 27.61009  ?  132 ASN A CA  1 
ATOM   837  C  C   . ASN A 1 132 ? 5.87130   -0.09756  -14.90943 1.000 25.96529  ?  132 ASN A C   1 
ATOM   838  O  O   . ASN A 1 132 ? 5.01739   0.38757   -14.15654 1.000 23.32380  ?  132 ASN A O   1 
ATOM   839  C  CB  . ASN A 1 132 ? 7.38558   -2.02907  -14.34126 1.000 28.05802  ?  132 ASN A CB  1 
ATOM   840  C  CG  . ASN A 1 132 ? 7.51533   -1.62066  -12.87927 1.000 32.32255  ?  132 ASN A CG  1 
ATOM   841  O  OD1 . ASN A 1 132 ? 7.33826   -0.45705  -12.51701 1.000 29.54673  ?  132 ASN A OD1 1 
ATOM   842  N  ND2 . ASN A 1 132 ? 7.83945   -2.58904  -12.03124 1.000 35.96876  ?  132 ASN A ND2 1 
ATOM   843  N  N   . ALA A 1 133 ? 6.65129   0.66083   -15.68312 1.000 21.86311  ?  133 ALA A N   1 
ATOM   844  C  CA  . ALA A 1 133 ? 6.66633   2.11163   -15.52755 1.000 23.76395  ?  133 ALA A CA  1 
ATOM   845  C  C   . ALA A 1 133 ? 5.38088   2.74635   -16.04704 1.000 25.72913  ?  133 ALA A C   1 
ATOM   846  O  O   . ALA A 1 133 ? 4.79571   3.61213   -15.38572 1.000 29.30365  ?  133 ALA A O   1 
ATOM   847  C  CB  . ALA A 1 133 ? 7.88608   2.69962   -16.23600 1.000 21.59248  ?  133 ALA A CB  1 
ATOM   848  N  N   . THR A 1 134 ? 4.91947   2.32805   -17.22515 1.000 20.40722  ?  134 THR A N   1 
ATOM   849  C  CA  . THR A 1 134 ? 3.73349   2.93763   -17.81523 1.000 21.28614  ?  134 THR A CA  1 
ATOM   850  C  C   . THR A 1 134 ? 2.43521   2.41126   -17.21660 1.000 26.03648  ?  134 THR A C   1 
ATOM   851  O  O   . THR A 1 134 ? 1.35786   2.77250   -17.70251 1.000 26.09096  ?  134 THR A O   1 
ATOM   852  C  CB  . THR A 1 134 ? 3.71779   2.73003   -19.33281 1.000 19.38884  ?  134 THR A CB  1 
ATOM   853  O  OG1 . THR A 1 134 ? 3.35803   1.37823   -19.62886 1.000 18.36127  ?  134 THR A OG1 1 
ATOM   854  C  CG2 . THR A 1 134 ? 5.08398   3.02425   -19.92404 1.000 17.59657  ?  134 THR A CG2 1 
ATOM   855  N  N   . TYR A 1 135 ? 2.50833   1.56432   -16.19177 1.000 26.51127  ?  135 TYR A N   1 
ATOM   856  C  CA  . TYR A 1 135 ? 1.33484   1.12232   -15.45170 1.000 24.53795  ?  135 TYR A CA  1 
ATOM   857  C  C   . TYR A 1 135 ? 1.10046   1.92734   -14.18138 1.000 30.34230  ?  135 TYR A C   1 
ATOM   858  O  O   . TYR A 1 135 ? 0.13138   1.66003   -13.46454 1.000 39.09221  ?  135 TYR A O   1 
ATOM   859  C  CB  . TYR A 1 135 ? 1.45684   -0.36381  -15.09907 1.000 23.80749  ?  135 TYR A CB  1 
ATOM   860  C  CG  . TYR A 1 135 ? 0.99763   -1.29782  -16.19409 1.000 22.48811  ?  135 TYR A CG  1 
ATOM   861  C  CD1 . TYR A 1 135 ? -0.31938  -1.73328  -16.25200 1.000 31.63239  ?  135 TYR A CD1 1 
ATOM   862  C  CD2 . TYR A 1 135 ? 1.87892   -1.74584  -17.16817 1.000 20.96940  ?  135 TYR A CD2 1 
ATOM   863  C  CE1 . TYR A 1 135 ? -0.74603  -2.58755  -17.24928 1.000 35.26256  ?  135 TYR A CE1 1 
ATOM   864  C  CE2 . TYR A 1 135 ? 1.46155   -2.60141  -18.17040 1.000 21.42961  ?  135 TYR A CE2 1 
ATOM   865  C  CZ  . TYR A 1 135 ? 0.14832   -3.01854  -18.20584 1.000 26.57465  ?  135 TYR A CZ  1 
ATOM   866  O  OH  . TYR A 1 135 ? -0.27331  -3.86995  -19.20056 1.000 29.71444  ?  135 TYR A OH  1 
ATOM   867  N  N   . ARG A 1 136 ? 1.95481   2.90119   -13.88781 1.000 31.66752  ?  136 ARG A N   1 
ATOM   868  C  CA  . ARG A 1 136 ? 1.85186   3.67248   -12.66070 1.000 30.83790  ?  136 ARG A CA  1 
ATOM   869  C  C   . ARG A 1 136 ? 0.89436   4.84832   -12.83695 1.000 30.03956  ?  136 ARG A C   1 
ATOM   870  O  O   . ARG A 1 136 ? 0.49666   5.20548   -13.94841 1.000 26.92744  ?  136 ARG A O   1 
ATOM   871  C  CB  . ARG A 1 136 ? 3.23091   4.16706   -12.22733 1.000 20.76876  ?  136 ARG A CB  1 
ATOM   872  C  CG  . ARG A 1 136 ? 4.27535   3.07145   -12.15291 1.000 19.50359  ?  136 ARG A CG  1 
ATOM   873  C  CD  . ARG A 1 136 ? 5.55458   3.56699   -11.50566 1.000 27.76480  ?  136 ARG A CD  1 
ATOM   874  N  NE  . ARG A 1 136 ? 6.56336   2.51701   -11.44219 1.000 29.83981  ?  136 ARG A NE  1 
ATOM   875  C  CZ  . ARG A 1 136 ? 7.70197   2.61052   -10.77012 1.000 28.42443  ?  136 ARG A CZ  1 
ATOM   876  N  NH1 . ARG A 1 136 ? 8.00881   3.69528   -10.07741 1.000 30.22839  ?  136 ARG A NH1 1 
ATOM   877  N  NH2 . ARG A 1 136 ? 8.55247   1.58856   -10.79098 1.000 31.52480  ?  136 ARG A NH2 1 
ATOM   878  N  N   . ASP A 1 137 ? 0.52264   5.45120   -11.71124 1.000 28.60007  ?  137 ASP A N   1 
ATOM   879  C  CA  . ASP A 1 137 ? -0.36198  6.60533   -11.73590 1.000 31.24687  ?  137 ASP A CA  1 
ATOM   880  C  C   . ASP A 1 137 ? 0.35452   7.82223   -12.31039 1.000 32.50316  ?  137 ASP A C   1 
ATOM   881  O  O   . ASP A 1 137 ? 1.56930   7.98516   -12.16345 1.000 36.10505  ?  137 ASP A O   1 
ATOM   882  C  CB  . ASP A 1 137 ? -0.87784  6.91628   -10.33038 1.000 32.87528  ?  137 ASP A CB  1 
ATOM   883  C  CG  . ASP A 1 137 ? -1.86424  5.88022   -9.82867  1.000 43.40582  ?  137 ASP A CG  1 
ATOM   884  O  OD1 . ASP A 1 137 ? -2.63356  5.34284   -10.65241 1.000 44.09458  ?  137 ASP A OD1 1 
ATOM   885  O  OD2 . ASP A 1 137 ? -1.87195  5.60378   -8.61062  1.000 51.52421  -1 137 ASP A OD2 1 
ATOM   886  N  N   . HIS A 1 138 ? -0.41965  8.67177   -12.98715 1.000 33.67754  ?  138 HIS A N   1 
ATOM   887  C  CA  . HIS A 1 138 ? 0.03404   9.93960   -13.55328 1.000 33.73080  ?  138 HIS A CA  1 
ATOM   888  C  C   . HIS A 1 138 ? 1.04806   9.76385   -14.67822 1.000 27.24864  ?  138 HIS A C   1 
ATOM   889  O  O   . HIS A 1 138 ? 1.81348   10.68836  -14.96938 1.000 29.11069  ?  138 HIS A O   1 
ATOM   890  C  CB  . HIS A 1 138 ? 0.61317   10.86038  -12.47052 1.000 33.72988  ?  138 HIS A CB  1 
ATOM   891  C  CG  . HIS A 1 138 ? -0.27270  11.01688  -11.27374 1.000 38.24994  ?  138 HIS A CG  1 
ATOM   892  N  ND1 . HIS A 1 138 ? -0.17177  10.20776  -10.16245 1.000 36.06025  ?  138 HIS A ND1 1 
ATOM   893  C  CD2 . HIS A 1 138 ? -1.27968  11.88493  -11.01649 1.000 40.97341  ?  138 HIS A CD2 1 
ATOM   894  C  CE1 . HIS A 1 138 ? -1.07569  10.57257  -9.27082  1.000 35.24669  ?  138 HIS A CE1 1 
ATOM   895  N  NE2 . HIS A 1 138 ? -1.76117  11.58803  -9.76448  1.000 43.44471  ?  138 HIS A NE2 1 
ATOM   896  N  N   . VAL A 1 139 ? 1.07385   8.60441   -15.32727 1.000 23.80373  ?  139 VAL A N   1 
ATOM   897  C  CA  . VAL A 1 139 ? 1.94551   8.37964   -16.47561 1.000 29.99435  ?  139 VAL A CA  1 
ATOM   898  C  C   . VAL A 1 139 ? 1.15406   8.68835   -17.74056 1.000 30.41306  ?  139 VAL A C   1 
ATOM   899  O  O   . VAL A 1 139 ? 0.08695   8.10959   -17.97208 1.000 27.60560  ?  139 VAL A O   1 
ATOM   900  C  CB  . VAL A 1 139 ? 2.48950   6.94327   -16.49494 1.000 28.69258  ?  139 VAL A CB  1 
ATOM   901  C  CG1 . VAL A 1 139 ? 3.37968   6.72894   -17.71115 1.000 19.19252  ?  139 VAL A CG1 1 
ATOM   902  C  CG2 . VAL A 1 139 ? 3.25786   6.65165   -15.21412 1.000 21.84590  ?  139 VAL A CG2 1 
ATOM   903  N  N   . TYR A 1 140 ? 1.67403   9.60383   -18.55561 1.000 31.26231  ?  140 TYR A N   1 
ATOM   904  C  CA  . TYR A 1 140 ? 1.00067   10.08380  -19.75178 1.000 30.80588  ?  140 TYR A CA  1 
ATOM   905  C  C   . TYR A 1 140 ? 1.81166   9.74344   -20.99528 1.000 33.09178  ?  140 TYR A C   1 
ATOM   906  O  O   . TYR A 1 140 ? 3.02988   9.54897   -20.93880 1.000 32.75426  ?  140 TYR A O   1 
ATOM   907  C  CB  . TYR A 1 140 ? 0.77639   11.60150  -19.69910 1.000 35.56232  ?  140 TYR A CB  1 
ATOM   908  C  CG  . TYR A 1 140 ? -0.18687  12.06484  -18.62970 1.000 37.11101  ?  140 TYR A CG  1 
ATOM   909  C  CD1 . TYR A 1 140 ? 0.25077   12.32359  -17.33748 1.000 37.61716  ?  140 TYR A CD1 1 
ATOM   910  C  CD2 . TYR A 1 140 ? -1.53141  12.26048  -18.91766 1.000 34.70698  ?  140 TYR A CD2 1 
ATOM   911  C  CE1 . TYR A 1 140 ? -0.62564  12.75355  -16.36005 1.000 42.80523  ?  140 TYR A CE1 1 
ATOM   912  C  CE2 . TYR A 1 140 ? -2.41460  12.69127  -17.94739 1.000 40.19746  ?  140 TYR A CE2 1 
ATOM   913  C  CZ  . TYR A 1 140 ? -1.95697  12.93546  -16.67067 1.000 44.75863  ?  140 TYR A CZ  1 
ATOM   914  O  OH  . TYR A 1 140 ? -2.83379  13.36342  -15.70084 1.000 51.80527  ?  140 TYR A OH  1 
ATOM   915  N  N   . MET A 1 141 ? 1.11160   9.69826   -22.12823 1.000 38.00788  ?  141 MET A N   1 
ATOM   916  C  CA  . MET A 1 141 ? 1.71149   9.42823   -23.42614 1.000 34.47367  ?  141 MET A CA  1 
ATOM   917  C  C   . MET A 1 141 ? 1.13583   10.39134  -24.45361 1.000 33.68945  ?  141 MET A C   1 
ATOM   918  O  O   . MET A 1 141 ? 0.06455   10.96966  -24.25970 1.000 37.43470  ?  141 MET A O   1 
ATOM   919  C  CB  . MET A 1 141 ? 1.45889   7.98856   -23.88467 1.000 26.47896  ?  141 MET A CB  1 
ATOM   920  C  CG  . MET A 1 141 ? -0.00540  7.68688   -24.15043 1.000 31.45946  ?  141 MET A CG  1 
ATOM   921  S  SD  . MET A 1 141 ? -0.23111  6.18709   -25.11674 1.000 28.65871  ?  141 MET A SD  1 
ATOM   922  C  CE  . MET A 1 141 ? 0.78240   5.04682   -24.18152 1.000 51.40790  ?  141 MET A CE  1 
ATOM   923  N  N   . CYS A 1 142 ? 1.86815   10.56290  -25.55173 1.000 33.68623  ?  142 CYS A N   1 
ATOM   924  C  CA  . CYS A 1 142 ? 1.36710   11.36187  -26.66477 1.000 30.06638  ?  142 CYS A CA  1 
ATOM   925  C  C   . CYS A 1 142 ? 2.17069   11.04945  -27.91968 1.000 34.16925  ?  142 CYS A C   1 
ATOM   926  O  O   . CYS A 1 142 ? 3.36195   10.74519  -27.84903 1.000 36.17337  ?  142 CYS A O   1 
ATOM   927  C  CB  . CYS A 1 142 ? 1.42569   12.86239  -26.35392 1.000 40.35785  ?  142 CYS A CB  1 
ATOM   928  S  SG  . CYS A 1 142 ? 3.04601   13.61009  -26.57600 1.000 49.25054  ?  142 CYS A SG  1 
ATOM   929  N  N   . MET A 1 143 ? 1.50828   11.13667  -29.07042 1.000 35.45834  ?  143 MET A N   1 
ATOM   930  C  CA  . MET A 1 143 ? 2.16146   10.91676  -30.35598 1.000 32.55691  ?  143 MET A CA  1 
ATOM   931  C  C   . MET A 1 143 ? 2.61432   12.25787  -30.92069 1.000 36.64174  ?  143 MET A C   1 
ATOM   932  O  O   . MET A 1 143 ? 1.78327   13.12405  -31.21591 1.000 38.99582  ?  143 MET A O   1 
ATOM   933  C  CB  . MET A 1 143 ? 1.22160   10.20831  -31.32929 1.000 23.80619  ?  143 MET A CB  1 
ATOM   934  C  CG  . MET A 1 143 ? 0.87813   8.78556   -30.92687 1.000 35.45314  ?  143 MET A CG  1 
ATOM   935  S  SD  . MET A 1 143 ? 2.33311   7.72389   -30.82009 1.000 27.32142  ?  143 MET A SD  1 
ATOM   936  C  CE  . MET A 1 143 ? 2.91588   7.77424   -32.51144 1.000 25.66347  ?  143 MET A CE  1 
ATOM   937  N  N   . ASP A 1 144 ? 3.92636   12.42392  -31.07790 1.000 30.20428  ?  144 ASP A N   1 
ATOM   938  C  CA  . ASP A 1 144 ? 4.49474   13.71163  -31.45544 1.000 37.50793  ?  144 ASP A CA  1 
ATOM   939  C  C   . ASP A 1 144 ? 4.34003   13.93917  -32.95915 1.000 39.13347  ?  144 ASP A C   1 
ATOM   940  O  O   . ASP A 1 144 ? 3.69083   13.16872  -33.67175 1.000 42.59113  ?  144 ASP A O   1 
ATOM   941  C  CB  . ASP A 1 144 ? 5.95165   13.80478  -30.99958 1.000 38.30154  ?  144 ASP A CB  1 
ATOM   942  C  CG  . ASP A 1 144 ? 6.86565   12.81385  -31.70676 1.000 34.70138  ?  144 ASP A CG  1 
ATOM   943  O  OD1 . ASP A 1 144 ? 6.38531   12.02374  -32.54330 1.000 33.26429  ?  144 ASP A OD1 1 
ATOM   944  O  OD2 . ASP A 1 144 ? 8.08180   12.82901  -31.42028 1.000 33.95799  -1 144 ASP A OD2 1 
ATOM   945  N  N   . GLN A 1 145 ? 4.95139   15.01508  -33.45702 1.000 44.40992  ?  145 GLN A N   1 
ATOM   946  C  CA  . GLN A 1 145 ? 4.85732   15.37028  -34.86677 1.000 51.83853  ?  145 GLN A CA  1 
ATOM   947  C  C   . GLN A 1 145 ? 5.61425   14.40614  -35.77142 1.000 46.59063  ?  145 GLN A C   1 
ATOM   948  O  O   . GLN A 1 145 ? 5.41875   14.44780  -36.99091 1.000 53.67389  ?  145 GLN A O   1 
ATOM   949  C  CB  . GLN A 1 145 ? 5.37798   16.79493  -35.07388 1.000 52.12015  ?  145 GLN A CB  1 
ATOM   950  C  CG  . GLN A 1 145 ? 4.93482   17.77826  -33.99643 1.000 66.13713  ?  145 GLN A CG  1 
ATOM   951  C  CD  . GLN A 1 145 ? 3.87268   18.74920  -34.47914 1.000 80.30832  ?  145 GLN A CD  1 
ATOM   952  O  OE1 . GLN A 1 145 ? 3.96197   19.28829  -35.58249 1.000 74.74209  ?  145 GLN A OE1 1 
ATOM   953  N  NE2 . GLN A 1 145 ? 2.85948   18.97743  -33.65070 1.000 73.14038  ?  145 GLN A NE2 1 
ATOM   954  N  N   . ASP A 1 146 ? 6.46460   13.54632  -35.21193 1.000 39.25931  ?  146 ASP A N   1 
ATOM   955  C  CA  . ASP A 1 146 ? 7.26036   12.60388  -35.98627 1.000 36.88091  ?  146 ASP A CA  1 
ATOM   956  C  C   . ASP A 1 146 ? 6.72342   11.17989  -35.91661 1.000 31.21073  ?  146 ASP A C   1 
ATOM   957  O  O   . ASP A 1 146 ? 7.42012   10.24763  -36.33017 1.000 24.13827  ?  146 ASP A O   1 
ATOM   958  C  CB  . ASP A 1 146 ? 8.71448   12.63484  -35.51359 1.000 33.38023  ?  146 ASP A CB  1 
ATOM   959  C  CG  . ASP A 1 146 ? 9.33566   14.00878  -35.63921 1.000 38.78719  ?  146 ASP A CG  1 
ATOM   960  O  OD1 . ASP A 1 146 ? 9.21663   14.61777  -36.72313 1.000 44.58442  ?  146 ASP A OD1 1 
ATOM   961  O  OD2 . ASP A 1 146 ? 9.93363   14.48365  -34.65088 1.000 53.31428  -1 146 ASP A OD2 1 
ATOM   962  N  N   . ASN A 1 147 ? 5.50300   10.99511  -35.40948 1.000 33.52930  ?  147 ASN A N   1 
ATOM   963  C  CA  . ASN A 1 147 ? 4.89167   9.67326   -35.25457 1.000 28.79062  ?  147 ASN A CA  1 
ATOM   964  C  C   . ASN A 1 147 ? 5.74268   8.77411   -34.35528 1.000 32.03480  ?  147 ASN A C   1 
ATOM   965  O  O   . ASN A 1 147 ? 5.99088   7.60355   -34.65405 1.000 32.61939  ?  147 ASN A O   1 
ATOM   966  C  CB  . ASN A 1 147 ? 4.63796   9.01948   -36.61577 1.000 26.78243  ?  147 ASN A CB  1 
ATOM   967  C  CG  . ASN A 1 147 ? 3.39018   8.16352   -36.62435 1.000 22.16235  ?  147 ASN A CG  1 
ATOM   968  O  OD1 . ASN A 1 147 ? 2.56626   8.24044   -35.71310 1.000 21.95363  ?  147 ASN A OD1 1 
ATOM   969  N  ND2 . ASN A 1 147 ? 3.23792   7.34900   -37.66105 1.000 18.77559  ?  147 ASN A ND2 1 
ATOM   970  N  N   . PHE A 1 148 ? 6.19567   9.34466   -33.24046 1.000 32.21844  ?  148 PHE A N   1 
ATOM   971  C  CA  . PHE A 1 148 ? 6.92168   8.62795   -32.19998 1.000 26.62739  ?  148 PHE A CA  1 
ATOM   972  C  C   . PHE A 1 148 ? 6.21197   8.84797   -30.87325 1.000 24.85473  ?  148 PHE A C   1 
ATOM   973  O  O   . PHE A 1 148 ? 5.84850   9.98129   -30.54302 1.000 30.21774  ?  148 PHE A O   1 
ATOM   974  C  CB  . PHE A 1 148 ? 8.37570   9.10084   -32.10122 1.000 22.50824  ?  148 PHE A CB  1 
ATOM   975  C  CG  . PHE A 1 148 ? 9.27322   8.53352   -33.15915 1.000 19.15290  ?  148 PHE A CG  1 
ATOM   976  C  CD1 . PHE A 1 148 ? 9.89989   7.31519   -32.96973 1.000 19.63554  ?  148 PHE A CD1 1 
ATOM   977  C  CD2 . PHE A 1 148 ? 9.49989   9.22180   -34.33770 1.000 24.66638  ?  148 PHE A CD2 1 
ATOM   978  C  CE1 . PHE A 1 148 ? 10.73240  6.79132   -33.93803 1.000 21.29092  ?  148 PHE A CE1 1 
ATOM   979  C  CE2 . PHE A 1 148 ? 10.32983  8.70171   -35.31242 1.000 22.31396  ?  148 PHE A CE2 1 
ATOM   980  C  CZ  . PHE A 1 148 ? 10.94656  7.48448   -35.11179 1.000 20.87564  ?  148 PHE A CZ  1 
ATOM   981  N  N   . VAL A 1 149 ? 6.01511   7.77389   -30.11793 1.000 24.15051  ?  149 VAL A N   1 
ATOM   982  C  CA  . VAL A 1 149 ? 5.32629   7.86962   -28.83660 1.000 29.90490  ?  149 VAL A CA  1 
ATOM   983  C  C   . VAL A 1 149 ? 6.26225   8.48221   -27.80253 1.000 27.12075  ?  149 VAL A C   1 
ATOM   984  O  O   . VAL A 1 149 ? 7.45414   8.15907   -27.74428 1.000 26.15896  ?  149 VAL A O   1 
ATOM   985  C  CB  . VAL A 1 149 ? 4.80650   6.48800   -28.39300 1.000 34.77808  ?  149 VAL A CB  1 
ATOM   986  C  CG1 . VAL A 1 149 ? 5.95540   5.52987   -28.11522 1.000 24.42030  ?  149 VAL A CG1 1 
ATOM   987  C  CG2 . VAL A 1 149 ? 3.90389   6.62227   -27.17383 1.000 34.15107  ?  149 VAL A CG2 1 
ATOM   988  N  N   . ARG A 1 150 ? 5.72563   9.39219   -26.99415 1.000 29.57557  ?  150 ARG A N   1 
ATOM   989  C  CA  . ARG A 1 150 ? 6.45709   10.04857  -25.92119 1.000 27.37721  ?  150 ARG A CA  1 
ATOM   990  C  C   . ARG A 1 150 ? 5.75090   9.74938   -24.60888 1.000 28.78493  ?  150 ARG A C   1 
ATOM   991  O  O   . ARG A 1 150 ? 4.52242   9.86064   -24.52551 1.000 36.63288  ?  150 ARG A O   1 
ATOM   992  C  CB  . ARG A 1 150 ? 6.52962   11.56341  -26.13971 1.000 28.62040  ?  150 ARG A CB  1 
ATOM   993  C  CG  . ARG A 1 150 ? 7.16959   12.00488  -27.44701 1.000 30.07574  ?  150 ARG A CG  1 
ATOM   994  C  CD  . ARG A 1 150 ? 8.68488   11.91427  -27.39097 1.000 32.25192  ?  150 ARG A CD  1 
ATOM   995  N  NE  . ARG A 1 150 ? 9.31954   12.82868  -28.33363 1.000 37.40239  ?  150 ARG A NE  1 
ATOM   996  C  CZ  . ARG A 1 150 ? 9.79065   14.02668  -28.01323 1.000 38.78614  ?  150 ARG A CZ  1 
ATOM   997  N  NH1 . ARG A 1 150 ? 9.73094   14.48412  -26.77299 1.000 35.48957  ?  150 ARG A NH1 1 
ATOM   998  N  NH2 . ARG A 1 150 ? 10.33784  14.78382  -28.96032 1.000 30.98054  ?  150 ARG A NH2 1 
ATOM   999  N  N   . LEU A 1 151 ? 6.52517   9.37568   -23.59317 1.000 24.53246  ?  151 LEU A N   1 
ATOM   1000 C  CA  . LEU A 1 151 ? 6.00815   9.04251   -22.27384 1.000 20.05818  ?  151 LEU A CA  1 
ATOM   1001 C  C   . LEU A 1 151 ? 6.58068   10.00430  -21.24354 1.000 22.86191  ?  151 LEU A C   1 
ATOM   1002 O  O   . LEU A 1 151 ? 7.76510   10.35037  -21.29534 1.000 29.64292  ?  151 LEU A O   1 
ATOM   1003 C  CB  . LEU A 1 151 ? 6.35969   7.60139   -21.88891 1.000 21.79800  ?  151 LEU A CB  1 
ATOM   1004 C  CG  . LEU A 1 151 ? 5.74828   6.48410   -22.73504 1.000 26.86465  ?  151 LEU A CG  1 
ATOM   1005 C  CD1 . LEU A 1 151 ? 6.47070   5.17297   -22.48500 1.000 20.53149  ?  151 LEU A CD1 1 
ATOM   1006 C  CD2 . LEU A 1 151 ? 4.26913   6.33991   -22.43050 1.000 34.45956  ?  151 LEU A CD2 1 
ATOM   1007 N  N   . THR A 1 152 ? 5.73745   10.43263  -20.30723 1.000 27.73327  ?  152 THR A N   1 
ATOM   1008 C  CA  . THR A 1 152 ? 6.16712   11.35296  -19.26282 1.000 33.50801  ?  152 THR A CA  1 
ATOM   1009 C  C   . THR A 1 152 ? 5.35791   11.08736  -18.00096 1.000 28.74559  ?  152 THR A C   1 
ATOM   1010 O  O   . THR A 1 152 ? 4.41803   10.28925  -17.99583 1.000 25.14046  ?  152 THR A O   1 
ATOM   1011 C  CB  . THR A 1 152 ? 6.01993   12.81662  -19.70227 1.000 30.79616  ?  152 THR A CB  1 
ATOM   1012 O  OG1 . THR A 1 152 ? 6.76306   13.66342  -18.81599 1.000 21.62065  ?  152 THR A OG1 1 
ATOM   1013 C  CG2 . THR A 1 152 ? 4.55716   13.23643  -19.67829 1.000 28.88669  ?  152 THR A CG2 1 
ATOM   1014 N  N   . VAL A 1 153 ? 5.74438   11.76125  -16.91945 1.000 25.88560  ?  153 VAL A N   1 
ATOM   1015 C  CA  . VAL A 1 153 ? 5.02933   11.70037  -15.64954 1.000 26.89310  ?  153 VAL A CA  1 
ATOM   1016 C  C   . VAL A 1 153 ? 4.72631   13.12661  -15.21021 1.000 32.34207  ?  153 VAL A C   1 
ATOM   1017 O  O   . VAL A 1 153 ? 5.64347   13.94544  -15.07415 1.000 24.30748  ?  153 VAL A O   1 
ATOM   1018 C  CB  . VAL A 1 153 ? 5.83123   10.95988  -14.56604 1.000 18.61517  ?  153 VAL A CB  1 
ATOM   1019 C  CG1 . VAL A 1 153 ? 5.03995   10.90315  -13.27337 1.000 17.40670  ?  153 VAL A CG1 1 
ATOM   1020 C  CG2 . VAL A 1 153 ? 6.19185   9.55905   -15.03299 1.000 23.93690  ?  153 VAL A CG2 1 
ATOM   1021 N  N   . SER A 1 154 ? 3.44616   13.42296  -14.99080 1.000 35.99185  ?  154 SER A N   1 
ATOM   1022 C  CA  . SER A 1 154 ? 3.01396   14.73300  -14.51513 1.000 37.97766  ?  154 SER A CA  1 
ATOM   1023 C  C   . SER A 1 154 ? 1.94922   14.52955  -13.44987 1.000 37.66373  ?  154 SER A C   1 
ATOM   1024 O  O   . SER A 1 154 ? 0.87667   13.99055  -13.73904 1.000 37.41643  ?  154 SER A O   1 
ATOM   1025 C  CB  . SER A 1 154 ? 2.47367   15.59220  -15.66307 1.000 45.34609  ?  154 SER A CB  1 
ATOM   1026 O  OG  . SER A 1 154 ? 1.96648   16.82588  -15.18406 1.000 44.83191  ?  154 SER A OG  1 
ATOM   1027 N  N   . GLY A 1 155 ? 2.24477   14.95900  -12.22003 1.000 37.83640  ?  155 GLY A N   1 
ATOM   1028 C  CA  . GLY A 1 155 ? 1.31216   14.76200  -11.12442 1.000 47.19682  ?  155 GLY A CA  1 
ATOM   1029 C  C   . GLY A 1 155 ? 0.20317   15.78748  -11.04137 1.000 60.28570  ?  155 GLY A C   1 
ATOM   1030 O  O   . GLY A 1 155 ? -0.83548  15.50959  -10.43256 1.000 57.91900  ?  155 GLY A O   1 
ATOM   1031 N  N   . THR A 1 156 ? 0.39735   16.96130  -11.63581 1.000 66.01902  ?  156 THR A N   1 
ATOM   1032 C  CA  . THR A 1 156 ? -0.59783  18.03409  -11.60034 1.000 55.09419  ?  156 THR A CA  1 
ATOM   1033 C  C   . THR A 1 156 ? -1.47082  17.99644  -12.85403 1.000 51.12516  ?  156 THR A C   1 
ATOM   1034 O  O   . THR A 1 156 ? -1.53990  18.94555  -13.63545 1.000 51.06015  ?  156 THR A O   1 
ATOM   1035 C  CB  . THR A 1 156 ? 0.08965   19.38807  -11.44198 1.000 47.93002  ?  156 THR A CB  1 
ATOM   1036 O  OG1 . THR A 1 156 ? 1.03212   19.57839  -12.50572 1.000 52.07369  ?  156 THR A OG1 1 
ATOM   1037 C  CG2 . THR A 1 156 ? 0.81686   19.46561  -10.10482 1.000 45.37717  ?  156 THR A CG2 1 
ATOM   1038 N  N   . GLY A 1 157 ? -2.14471  16.86365  -13.03790 1.000 63.45976  ?  157 GLY A N   1 
ATOM   1039 C  CA  . GLY A 1 157 ? -3.01459  16.67053  -14.17231 1.000 66.68436  ?  157 GLY A CA  1 
ATOM   1040 C  C   . GLY A 1 157 ? -2.23241  16.47696  -15.45375 1.000 60.21970  ?  157 GLY A C   1 
ATOM   1041 O  O   . GLY A 1 157 ? -1.01176  16.28740  -15.43861 1.000 58.29547  ?  157 GLY A O   1 
ATOM   1042 N  N   . PRO A 1 158 ? -2.92286  16.51828  -16.59001 1.000 60.41692  ?  158 PRO A N   1 
ATOM   1043 C  CA  . PRO A 1 158 ? -2.24326  16.37479  -17.88312 1.000 64.96341  ?  158 PRO A CA  1 
ATOM   1044 C  C   . PRO A 1 158 ? -1.22546  17.48206  -18.08557 1.000 63.61809  ?  158 PRO A C   1 
ATOM   1045 O  O   . PRO A 1 158 ? -1.45533  18.63170  -17.67966 1.000 49.20718  ?  158 PRO A O   1 
ATOM   1046 C  CB  . PRO A 1 158 ? -3.39119  16.47098  -18.90168 1.000 54.27218  ?  158 PRO A CB  1 
ATOM   1047 C  CG  . PRO A 1 158 ? -4.50033  17.15533  -18.17044 1.000 56.70321  ?  158 PRO A CG  1 
ATOM   1048 C  CD  . PRO A 1 158 ? -4.37350  16.71556  -16.74424 1.000 60.13054  ?  158 PRO A CD  1 
ATOM   1049 N  N   . PRO A 1 159 ? -0.08702  17.17785  -18.70491 1.000 62.55509  ?  159 PRO A N   1 
ATOM   1050 C  CA  . PRO A 1 159 ? 0.96785   18.18654  -18.83331 1.000 63.92704  ?  159 PRO A CA  1 
ATOM   1051 C  C   . PRO A 1 159 ? 0.60107   19.25866  -19.84570 1.000 67.81346  ?  159 PRO A C   1 
ATOM   1052 O  O   . PRO A 1 159 ? -0.16446  19.03001  -20.78573 1.000 54.60148  ?  159 PRO A O   1 
ATOM   1053 C  CB  . PRO A 1 159 ? 2.18783   17.37633  -19.28852 1.000 50.23300  ?  159 PRO A CB  1 
ATOM   1054 C  CG  . PRO A 1 159 ? 1.64605   16.07821  -19.82366 1.000 50.34122  ?  159 PRO A CG  1 
ATOM   1055 C  CD  . PRO A 1 159 ? 0.17153   15.99387  -19.53954 1.000 52.96806  ?  159 PRO A CD  1 
ATOM   1056 N  N   . ALA A 1 160 ? 1.16494   20.44560  -19.63860 1.000 69.98338  ?  160 ALA A N   1 
ATOM   1057 C  CA  . ALA A 1 160 ? 0.86427   21.60626  -20.47250 1.000 68.93878  ?  160 ALA A CA  1 
ATOM   1058 C  C   . ALA A 1 160 ? 1.69393   21.52497  -21.74677 1.000 61.74375  ?  160 ALA A C   1 
ATOM   1059 O  O   . ALA A 1 160 ? 2.89362   21.81094  -21.74180 1.000 61.00054  ?  160 ALA A O   1 
ATOM   1060 C  CB  . ALA A 1 160 ? 1.14088   22.89764  -19.71134 1.000 50.13728  ?  160 ALA A CB  1 
ATOM   1061 N  N   . ASN A 1 161 ? 1.05400   21.13097  -22.84705 1.000 57.07011  ?  161 ASN A N   1 
ATOM   1062 C  CA  . ASN A 1 161 ? 1.71901   21.10181  -24.14355 1.000 68.41780  ?  161 ASN A CA  1 
ATOM   1063 C  C   . ASN A 1 161 ? 0.66796   21.06641  -25.24128 1.000 58.65473  ?  161 ASN A C   1 
ATOM   1064 O  O   . ASN A 1 161 ? -0.26369  20.25746  -25.18520 1.000 46.40510  ?  161 ASN A O   1 
ATOM   1065 C  CB  . ASN A 1 161 ? 2.65511   19.89496  -24.26551 1.000 59.73967  ?  161 ASN A CB  1 
ATOM   1066 C  CG  . ASN A 1 161 ? 3.46532   19.91497  -25.54801 1.000 69.02915  ?  161 ASN A CG  1 
ATOM   1067 O  OD1 . ASN A 1 161 ? 3.59747   20.95383  -26.19575 1.000 60.33500  ?  161 ASN A OD1 1 
ATOM   1068 N  ND2 . ASN A 1 161 ? 4.01542   18.76483  -25.91970 1.000 76.93767  ?  161 ASN A ND2 1 
ATOM   1069 N  N   . SER A 1 162 ? 0.82415   21.94266  -26.23453 1.000 59.21068  ?  162 SER A N   1 
ATOM   1070 C  CA  . SER A 1 162 ? -0.05083  21.95973  -27.39787 1.000 65.85400  ?  162 SER A CA  1 
ATOM   1071 C  C   . SER A 1 162 ? 0.57838   21.31678  -28.62494 1.000 65.53017  ?  162 SER A C   1 
ATOM   1072 O  O   . SER A 1 162 ? -0.14730  20.96498  -29.56179 1.000 59.07422  ?  162 SER A O   1 
ATOM   1073 C  CB  . SER A 1 162 ? -0.45775  23.39824  -27.73875 1.000 65.29522  ?  162 SER A CB  1 
ATOM   1074 O  OG  . SER A 1 162 ? -1.30051  23.43573  -28.87794 1.000 67.33998  ?  162 SER A OG  1 
ATOM   1075 N  N   . GLY A 1 163 ? 1.90122   21.15136  -28.64065 1.000 60.64856  ?  163 GLY A N   1 
ATOM   1076 C  CA  . GLY A 1 163 ? 2.56129   20.47069  -29.73610 1.000 57.82145  ?  163 GLY A CA  1 
ATOM   1077 C  C   . GLY A 1 163 ? 2.40244   18.97073  -29.73075 1.000 58.09933  ?  163 GLY A C   1 
ATOM   1078 O  O   . GLY A 1 163 ? 2.81672   18.30982  -30.68915 1.000 58.60872  ?  163 GLY A O   1 
ATOM   1079 N  N   . CYS A 1 164 ? 1.81218   18.42024  -28.67203 1.000 56.18694  ?  164 CYS A N   1 
ATOM   1080 C  CA  . CYS A 1 164 ? 1.58305   16.98366  -28.56585 1.000 49.43177  ?  164 CYS A CA  1 
ATOM   1081 C  C   . CYS A 1 164 ? 0.37815   16.76857  -27.66487 1.000 53.03339  ?  164 CYS A C   1 
ATOM   1082 O  O   . CYS A 1 164 ? 0.37150   17.22947  -26.51949 1.000 64.58913  ?  164 CYS A O   1 
ATOM   1083 C  CB  . CYS A 1 164 ? 2.81736   16.27404  -28.01095 1.000 43.63429  ?  164 CYS A CB  1 
ATOM   1084 S  SG  . CYS A 1 164 ? 2.92319   14.51509  -28.38806 1.000 57.61135  ?  164 CYS A SG  1 
ATOM   1085 N  N   . GLU A 1 165 ? -0.63606  16.07948  -28.18042 1.000 43.81905  ?  165 GLU A N   1 
ATOM   1086 C  CA  . GLU A 1 165 ? -1.88447  15.88109  -27.45108 1.000 40.94152  ?  165 GLU A CA  1 
ATOM   1087 C  C   . GLU A 1 165 ? -1.69880  14.74545  -26.45191 1.000 44.22951  ?  165 GLU A C   1 
ATOM   1088 O  O   . GLU A 1 165 ? -1.63936  13.57291  -26.83658 1.000 42.74878  ?  165 GLU A O   1 
ATOM   1089 C  CB  . GLU A 1 165 ? -3.02164  15.58498  -28.42393 1.000 53.43451  ?  165 GLU A CB  1 
ATOM   1090 C  CG  . GLU A 1 165 ? -4.41063  15.74379  -27.83310 1.000 58.45381  ?  165 GLU A CG  1 
ATOM   1091 C  CD  . GLU A 1 165 ? -5.50270  15.56199  -28.86857 1.000 92.49860  ?  165 GLU A CD  1 
ATOM   1092 O  OE1 . GLU A 1 165 ? -5.18736  15.12222  -29.99457 1.000 86.33366  ?  165 GLU A OE1 1 
ATOM   1093 O  OE2 . GLU A 1 165 ? -6.67478  15.86242  -28.55871 1.000 124.10824 -1 165 GLU A OE2 1 
ATOM   1094 N  N   . TRP A 1 166 ? -1.61745  15.09027  -25.16876 1.000 49.30836  ?  166 TRP A N   1 
ATOM   1095 C  CA  . TRP A 1 166 ? -1.31471  14.11348  -24.13108 1.000 44.68637  ?  166 TRP A CA  1 
ATOM   1096 C  C   . TRP A 1 166 ? -2.57000  13.36473  -23.70072 1.000 39.57155  ?  166 TRP A C   1 
ATOM   1097 O  O   . TRP A 1 166 ? -3.62186  13.97063  -23.47211 1.000 52.68213  ?  166 TRP A O   1 
ATOM   1098 C  CB  . TRP A 1 166 ? -0.67523  14.80013  -22.92526 1.000 41.44133  ?  166 TRP A CB  1 
ATOM   1099 C  CG  . TRP A 1 166 ? 0.70286   15.31027  -23.19140 1.000 39.27900  ?  166 TRP A CG  1 
ATOM   1100 C  CD1 . TRP A 1 166 ? 1.05841   16.58922  -23.50481 1.000 48.96271  ?  166 TRP A CD1 1 
ATOM   1101 C  CD2 . TRP A 1 166 ? 1.91541   14.54930  -23.17180 1.000 38.37179  ?  166 TRP A CD2 1 
ATOM   1102 N  NE1 . TRP A 1 166 ? 2.41866   16.67250  -23.67881 1.000 49.88927  ?  166 TRP A NE1 1 
ATOM   1103 C  CE2 . TRP A 1 166 ? 2.96823   15.43330  -23.48040 1.000 47.35547  ?  166 TRP A CE2 1 
ATOM   1104 C  CE3 . TRP A 1 166 ? 2.21320   13.20666  -22.92144 1.000 34.29623  ?  166 TRP A CE3 1 
ATOM   1105 C  CZ2 . TRP A 1 166 ? 4.29732   15.01809  -23.54579 1.000 42.92785  ?  166 TRP A CZ2 1 
ATOM   1106 C  CZ3 . TRP A 1 166 ? 3.53213   12.79569  -22.98921 1.000 38.31095  ?  166 TRP A CZ3 1 
ATOM   1107 C  CH2 . TRP A 1 166 ? 4.55806   13.69865  -23.29720 1.000 34.27035  ?  166 TRP A CH2 1 
ATOM   1108 N  N   . LYS A 1 167 ? -2.45123  12.04372  -23.58945 1.000 31.22236  ?  167 LYS A N   1 
ATOM   1109 C  CA  . LYS A 1 167 ? -3.51617  11.18137  -23.10112 1.000 36.70823  ?  167 LYS A CA  1 
ATOM   1110 C  C   . LYS A 1 167 ? -2.96193  10.27622  -22.01125 1.000 34.57498  ?  167 LYS A C   1 
ATOM   1111 O  O   . LYS A 1 167 ? -1.82392  9.80692   -22.10478 1.000 32.34291  ?  167 LYS A O   1 
ATOM   1112 C  CB  . LYS A 1 167 ? -4.11524  10.33658  -24.23310 1.000 40.87491  ?  167 LYS A CB  1 
ATOM   1113 C  CG  . LYS A 1 167 ? -4.71064  11.15109  -25.37128 1.000 46.17066  ?  167 LYS A CG  1 
ATOM   1114 C  CD  . LYS A 1 167 ? -5.26186  10.25104  -26.46538 1.000 42.73459  ?  167 LYS A CD  1 
ATOM   1115 C  CE  . LYS A 1 167 ? -5.91971  11.06075  -27.57059 1.000 55.52320  ?  167 LYS A CE  1 
ATOM   1116 N  NZ  . LYS A 1 167 ? -6.45721  10.18650  -28.64969 1.000 76.29110  ?  167 LYS A NZ  1 
ATOM   1117 N  N   . LEU A 1 168 ? -3.76576  10.04061  -20.97605 1.000 39.50001  ?  168 LEU A N   1 
ATOM   1118 C  CA  . LEU A 1 168 ? -3.34873  9.16777   -19.88552 1.000 42.09748  ?  168 LEU A CA  1 
ATOM   1119 C  C   . LEU A 1 168 ? -3.18435  7.73763   -20.38992 1.000 41.07874  ?  168 LEU A C   1 
ATOM   1120 O  O   . LEU A 1 168 ? -4.04255  7.22020   -21.11105 1.000 44.06241  ?  168 LEU A O   1 
ATOM   1121 C  CB  . LEU A 1 168 ? -4.36914  9.21812   -18.74863 1.000 36.93890  ?  168 LEU A CB  1 
ATOM   1122 C  CG  . LEU A 1 168 ? -3.97565  8.57498   -17.41630 1.000 34.19579  ?  168 LEU A CG  1 
ATOM   1123 C  CD1 . LEU A 1 168 ? -2.96653  9.43623   -16.67132 1.000 27.66485  ?  168 LEU A CD1 1 
ATOM   1124 C  CD2 . LEU A 1 168 ? -5.20467  8.32003   -16.55860 1.000 28.44422  ?  168 LEU A CD2 1 
ATOM   1125 N  N   . VAL A 1 169 ? -2.07999  7.09515   -20.00029 1.000 38.43693  ?  169 VAL A N   1 
ATOM   1126 C  CA  . VAL A 1 169 ? -1.78350  5.75434   -20.49826 1.000 43.17345  ?  169 VAL A CA  1 
ATOM   1127 C  C   . VAL A 1 169 ? -2.81055  4.74424   -20.00100 1.000 47.67908  ?  169 VAL A C   1 
ATOM   1128 O  O   . VAL A 1 169 ? -3.14608  3.79085   -20.71420 1.000 46.23147  ?  169 VAL A O   1 
ATOM   1129 C  CB  . VAL A 1 169 ? -0.35100  5.34287   -20.10792 1.000 39.65796  ?  169 VAL A CB  1 
ATOM   1130 C  CG1 . VAL A 1 169 ? -0.02437  3.95647   -20.64840 1.000 26.46685  ?  169 VAL A CG1 1 
ATOM   1131 C  CG2 . VAL A 1 169 ? 0.65185   6.36276   -20.62333 1.000 32.02270  ?  169 VAL A CG2 1 
ATOM   1132 N  N   . GLU A 1 170 ? -3.31817  4.92246   -18.77900 1.000 44.75706  ?  170 GLU A N   1 
ATOM   1133 C  CA  . GLU A 1 170 ? -4.29672  3.98452   -18.23541 1.000 46.10825  ?  170 GLU A CA  1 
ATOM   1134 C  C   . GLU A 1 170 ? -5.55234  3.93669   -19.09938 1.000 45.88928  ?  170 GLU A C   1 
ATOM   1135 O  O   . GLU A 1 170 ? -6.02577  2.85465   -19.47290 1.000 45.12362  ?  170 GLU A O   1 
ATOM   1136 C  CB  . GLU A 1 170 ? -4.64309  4.37426   -16.79749 1.000 44.28419  ?  170 GLU A CB  1 
ATOM   1137 C  CG  . GLU A 1 170 ? -5.57422  3.40669   -16.08622 1.000 51.07805  ?  170 GLU A CG  1 
ATOM   1138 C  CD  . GLU A 1 170 ? -5.94712  3.87961   -14.69354 1.000 64.76438  ?  170 GLU A CD  1 
ATOM   1139 O  OE1 . GLU A 1 170 ? -5.57752  5.01704   -14.33199 1.000 60.82459  ?  170 GLU A OE1 1 
ATOM   1140 O  OE2 . GLU A 1 170 ? -6.60953  3.11507   -13.96053 1.000 68.89358  -1 170 GLU A OE2 1 
ATOM   1141 N  N   . THR A 1 171 ? -6.09732  5.10732   -19.44182 1.000 40.84109  ?  171 THR A N   1 
ATOM   1142 C  CA  . THR A 1 171 ? -7.30716  5.14576   -20.25661 1.000 47.14898  ?  171 THR A CA  1 
ATOM   1143 C  C   . THR A 1 171 ? -7.05364  4.59009   -21.65281 1.000 54.40545  ?  171 THR A C   1 
ATOM   1144 O  O   . THR A 1 171 ? -7.89900  3.87653   -22.20012 1.000 58.45740  ?  171 THR A O   1 
ATOM   1145 C  CB  . THR A 1 171 ? -7.85280  6.57282   -20.33827 1.000 42.05633  ?  171 THR A CB  1 
ATOM   1146 O  OG1 . THR A 1 171 ? -6.96533  7.38745   -21.11371 1.000 52.75682  ?  171 THR A OG1 1 
ATOM   1147 C  CG2 . THR A 1 171 ? -7.99477  7.17037   -18.94536 1.000 46.26983  ?  171 THR A CG2 1 
ATOM   1148 N  N   . GLU A 1 172 ? -5.89900  4.90527   -22.24652 1.000 47.08786  ?  172 GLU A N   1 
ATOM   1149 C  CA  . GLU A 1 172 ? -5.59567  4.40111   -23.58378 1.000 38.76033  ?  172 GLU A CA  1 
ATOM   1150 C  C   . GLU A 1 172 ? -5.45577  2.88313   -23.58764 1.000 35.84543  ?  172 GLU A C   1 
ATOM   1151 O  O   . GLU A 1 172 ? -5.93737  2.21082   -24.50836 1.000 36.42696  ?  172 GLU A O   1 
ATOM   1152 C  CB  . GLU A 1 172 ? -4.32528  5.06177   -24.11720 1.000 44.24776  ?  172 GLU A CB  1 
ATOM   1153 C  CG  . GLU A 1 172 ? -4.41312  6.57589   -24.20602 1.000 42.45433  ?  172 GLU A CG  1 
ATOM   1154 C  CD  . GLU A 1 172 ? -5.54236  7.04197   -25.10222 1.000 43.60428  ?  172 GLU A CD  1 
ATOM   1155 O  OE1 . GLU A 1 172 ? -5.53349  6.69468   -26.30176 1.000 40.09462  ?  172 GLU A OE1 1 
ATOM   1156 O  OE2 . GLU A 1 172 ? -6.44400  7.74889   -24.60454 1.000 58.90583  -1 172 GLU A OE2 1 
ATOM   1157 N  N   . ARG A 1 173 ? -4.79866  2.32593   -22.56784 1.000 35.53263  ?  173 ARG A N   1 
ATOM   1158 C  CA  . ARG A 1 173 ? -4.68910  0.87510   -22.46257 1.000 37.63226  ?  173 ARG A CA  1 
ATOM   1159 C  C   . ARG A 1 173 ? -6.05644  0.23700   -22.25288 1.000 36.50308  ?  173 ARG A C   1 
ATOM   1160 O  O   . ARG A 1 173 ? -6.33629  -0.84012  -22.79229 1.000 24.02720  ?  173 ARG A O   1 
ATOM   1161 C  CB  . ARG A 1 173 ? -3.73466  0.49999   -21.32707 1.000 38.13855  ?  173 ARG A CB  1 
ATOM   1162 C  CG  . ARG A 1 173 ? -3.57343  -0.99987  -21.12124 1.000 32.65197  ?  173 ARG A CG  1 
ATOM   1163 C  CD  . ARG A 1 173 ? -2.59698  -1.32396  -19.99675 1.000 26.64683  ?  173 ARG A CD  1 
ATOM   1164 N  NE  . ARG A 1 173 ? -1.20477  -1.14363  -20.39329 1.000 29.93827  ?  173 ARG A NE  1 
ATOM   1165 C  CZ  . ARG A 1 173 ? -0.42935  -0.14637  -19.98922 1.000 31.66296  ?  173 ARG A CZ  1 
ATOM   1166 N  NH1 . ARG A 1 173 ? -0.87617  0.78728   -19.16505 1.000 37.30229  ?  173 ARG A NH1 1 
ATOM   1167 N  NH2 . ARG A 1 173 ? 0.82832   -0.08775  -20.41834 1.000 23.13035  ?  173 ARG A NH2 1 
ATOM   1168 N  N   . ALA A 1 174 ? -6.92145  0.88392   -21.46625 1.000 41.09482  ?  174 ALA A N   1 
ATOM   1169 C  CA  . ALA A 1 174 ? -8.27795  0.37277   -21.29385 1.000 37.98703  ?  174 ALA A CA  1 
ATOM   1170 C  C   . ALA A 1 174 ? -9.04665  0.38567   -22.61039 1.000 39.21374  ?  174 ALA A C   1 
ATOM   1171 O  O   . ALA A 1 174 ? -9.76259  -0.57023  -22.93081 1.000 53.10568  ?  174 ALA A O   1 
ATOM   1172 C  CB  . ALA A 1 174 ? -9.01558  1.18913   -20.23388 1.000 40.50056  ?  174 ALA A CB  1 
ATOM   1173 N  N   . ASN A 1 175 ? -8.90818  1.46039   -23.38756 1.000 34.44386  ?  175 ASN A N   1 
ATOM   1174 C  CA  . ASN A 1 175 ? -9.64004  1.59500   -24.64123 1.000 40.00394  ?  175 ASN A CA  1 
ATOM   1175 C  C   . ASN A 1 175 ? -9.05279  0.75338   -25.76572 1.000 42.17275  ?  175 ASN A C   1 
ATOM   1176 O  O   . ASN A 1 175 ? -9.72507  0.55362   -26.78346 1.000 40.32563  ?  175 ASN A O   1 
ATOM   1177 C  CB  . ASN A 1 175 ? -9.67529  3.06053   -25.08463 1.000 49.94720  ?  175 ASN A CB  1 
ATOM   1178 C  CG  . ASN A 1 175 ? -10.13558 3.99651   -23.98447 1.000 48.01172  ?  175 ASN A CG  1 
ATOM   1179 O  OD1 . ASN A 1 175 ? -10.80263 3.58291   -23.03565 1.000 52.70859  ?  175 ASN A OD1 1 
ATOM   1180 N  ND2 . ASN A 1 175 ? -9.77229  5.26869   -24.10335 1.000 36.04716  ?  175 ASN A ND2 1 
ATOM   1181 N  N   . SER A 1 176 ? -7.81689  0.26912   -25.61390 1.000 46.26386  ?  176 SER A N   1 
ATOM   1182 C  CA  . SER A 1 176 ? -7.19389  -0.50776  -26.68141 1.000 45.19394  ?  176 SER A CA  1 
ATOM   1183 C  C   . SER A 1 176 ? -7.94959  -1.80100  -26.95760 1.000 49.15618  ?  176 SER A C   1 
ATOM   1184 O  O   . SER A 1 176 ? -7.99028  -2.26233  -28.10401 1.000 58.10386  ?  176 SER A O   1 
ATOM   1185 C  CB  . SER A 1 176 ? -5.73894  -0.81664  -26.32864 1.000 48.88856  ?  176 SER A CB  1 
ATOM   1186 O  OG  . SER A 1 176 ? -5.65990  -1.78917  -25.30113 1.000 46.76233  ?  176 SER A OG  1 
ATOM   1187 N  N   . GLY A 1 177 ? -8.54979  -2.39810  -25.93147 1.000 49.06758  ?  177 GLY A N   1 
ATOM   1188 C  CA  . GLY A 1 177 ? -9.22262  -3.67135  -26.09188 1.000 41.57032  ?  177 GLY A CA  1 
ATOM   1189 C  C   . GLY A 1 177 ? -8.28059  -4.84182  -25.90533 1.000 47.59880  ?  177 GLY A C   1 
ATOM   1190 O  O   . GLY A 1 177 ? -8.51298  -5.70687  -25.05549 1.000 59.88529  ?  177 GLY A O   1 
ATOM   1191 N  N   . ASP A 1 178 ? -7.21041  -4.87805  -26.69670 1.000 43.56104  ?  178 ASP A N   1 
ATOM   1192 C  CA  . ASP A 1 178 ? -6.17299  -5.90127  -26.58445 1.000 38.85598  ?  178 ASP A CA  1 
ATOM   1193 C  C   . ASP A 1 178 ? -4.97502  -5.26580  -25.88535 1.000 38.85895  ?  178 ASP A C   1 
ATOM   1194 O  O   . ASP A 1 178 ? -4.20002  -4.52926  -26.50061 1.000 44.21703  ?  178 ASP A O   1 
ATOM   1195 C  CB  . ASP A 1 178 ? -5.80396  -6.45362  -27.95722 1.000 35.35769  ?  178 ASP A CB  1 
ATOM   1196 C  CG  . ASP A 1 178 ? -4.93675  -7.69643  -27.87433 1.000 44.83436  ?  178 ASP A CG  1 
ATOM   1197 O  OD1 . ASP A 1 178 ? -4.54993  -8.08570  -26.75201 1.000 50.77561  ?  178 ASP A OD1 1 
ATOM   1198 O  OD2 . ASP A 1 178 ? -4.64555  -8.28908  -28.93484 1.000 44.49123  -1 178 ASP A OD2 1 
ATOM   1199 N  N   . ILE A 1 179 ? -4.82745  -5.55777  -24.59166 1.000 34.92079  ?  179 ILE A N   1 
ATOM   1200 C  CA  . ILE A 1 179 ? -3.78691  -4.91806  -23.79208 1.000 33.68466  ?  179 ILE A CA  1 
ATOM   1201 C  C   . ILE A 1 179 ? -2.40414  -5.41367  -24.20047 1.000 36.57535  ?  179 ILE A C   1 
ATOM   1202 O  O   . ILE A 1 179 ? -1.44179  -4.63684  -24.24617 1.000 36.20317  ?  179 ILE A O   1 
ATOM   1203 C  CB  . ILE A 1 179 ? -4.05753  -5.14732  -22.29372 1.000 34.73705  ?  179 ILE A CB  1 
ATOM   1204 C  CG1 . ILE A 1 179 ? -5.35578  -4.45245  -21.87770 1.000 35.49781  ?  179 ILE A CG1 1 
ATOM   1205 C  CG2 . ILE A 1 179 ? -2.89320  -4.65176  -21.45103 1.000 33.36736  ?  179 ILE A CG2 1 
ATOM   1206 C  CD1 . ILE A 1 179 ? -5.68894  -4.60674  -20.41016 1.000 29.78268  ?  179 ILE A CD1 1 
ATOM   1207 N  N   . ALA A 1 180 ? -2.27656  -6.71135  -24.49165 1.000 37.71701  ?  180 ALA A N   1 
ATOM   1208 C  CA  . ALA A 1 180 ? -0.97626  -7.25777  -24.87053 1.000 31.51730  ?  180 ALA A CA  1 
ATOM   1209 C  C   . ALA A 1 180 ? -0.46410  -6.62349  -26.15754 1.000 36.89923  ?  180 ALA A C   1 
ATOM   1210 O  O   . ALA A 1 180 ? 0.71934   -6.27496  -26.26060 1.000 30.76039  ?  180 ALA A O   1 
ATOM   1211 C  CB  . ALA A 1 180 ? -1.06734  -8.77593  -25.01808 1.000 18.86447  ?  180 ALA A CB  1 
ATOM   1212 N  N   . ALA A 1 181 ? -1.34399  -6.46118  -27.14887 1.000 36.56648  ?  181 ALA A N   1 
ATOM   1213 C  CA  . ALA A 1 181 ? -0.95386  -5.78623  -28.38142 1.000 31.74915  ?  181 ALA A CA  1 
ATOM   1214 C  C   . ALA A 1 181 ? -0.57617  -4.33630  -28.11439 1.000 32.26249  ?  181 ALA A C   1 
ATOM   1215 O  O   . ALA A 1 181 ? 0.35705   -3.80763  -28.72747 1.000 33.76849  ?  181 ALA A O   1 
ATOM   1216 C  CB  . ALA A 1 181 ? -2.08376  -5.86773  -29.40707 1.000 40.32215  ?  181 ALA A CB  1 
ATOM   1217 N  N   . PHE A 1 182 ? -1.29329  -3.67704  -27.20141 1.000 32.52445  ?  182 PHE A N   1 
ATOM   1218 C  CA  . PHE A 1 182 ? -0.97106  -2.29619  -26.85705 1.000 27.86998  ?  182 PHE A CA  1 
ATOM   1219 C  C   . PHE A 1 182 ? 0.42260   -2.18823  -26.24923 1.000 30.23071  ?  182 PHE A C   1 
ATOM   1220 O  O   . PHE A 1 182 ? 1.19987   -1.30023  -26.61617 1.000 28.80389  ?  182 PHE A O   1 
ATOM   1221 C  CB  . PHE A 1 182 ? -2.02776  -1.74406  -25.89936 1.000 25.35466  ?  182 PHE A CB  1 
ATOM   1222 C  CG  . PHE A 1 182 ? -1.74556  -0.35133  -25.41566 1.000 23.80505  ?  182 PHE A CG  1 
ATOM   1223 C  CD1 . PHE A 1 182 ? -2.00254  0.74252   -26.22375 1.000 27.10688  ?  182 PHE A CD1 1 
ATOM   1224 C  CD2 . PHE A 1 182 ? -1.23645  -0.13549  -24.14607 1.000 25.88812  ?  182 PHE A CD2 1 
ATOM   1225 C  CE1 . PHE A 1 182 ? -1.74750  2.02441   -25.77863 1.000 26.76006  ?  182 PHE A CE1 1 
ATOM   1226 C  CE2 . PHE A 1 182 ? -0.98014  1.14324   -23.69550 1.000 26.96444  ?  182 PHE A CE2 1 
ATOM   1227 C  CZ  . PHE A 1 182 ? -1.23721  2.22406   -24.51266 1.000 29.81127  ?  182 PHE A CZ  1 
ATOM   1228 N  N   . ASP A 1 183 ? 0.76178   -3.09182  -25.32587 1.000 29.83110  ?  183 ASP A N   1 
ATOM   1229 C  CA  . ASP A 1 183 ? 2.09151   -3.06897  -24.72055 1.000 31.65850  ?  183 ASP A CA  1 
ATOM   1230 C  C   . ASP A 1 183 ? 3.17288   -3.40541  -25.74089 1.000 33.70855  ?  183 ASP A C   1 
ATOM   1231 O  O   . ASP A 1 183 ? 4.25599   -2.80161  -25.73435 1.000 31.47967  ?  183 ASP A O   1 
ATOM   1232 C  CB  . ASP A 1 183 ? 2.15033   -4.03783  -23.54053 1.000 30.12782  ?  183 ASP A CB  1 
ATOM   1233 C  CG  . ASP A 1 183 ? 1.23043   -3.63313  -22.40936 1.000 27.44564  ?  183 ASP A CG  1 
ATOM   1234 O  OD1 . ASP A 1 183 ? 0.91458   -2.42926  -22.30285 1.000 25.89149  ?  183 ASP A OD1 1 
ATOM   1235 O  OD2 . ASP A 1 183 ? 0.82644   -4.51822  -21.62564 1.000 27.46186  -1 183 ASP A OD2 1 
ATOM   1236 N  N   . HIS A 1 184 ? 2.90323   -4.37080  -26.62314 1.000 34.83591  ?  184 HIS A N   1 
ATOM   1237 C  CA  . HIS A 1 184 ? 3.88017   -4.70339  -27.65247 1.000 32.76943  ?  184 HIS A CA  1 
ATOM   1238 C  C   . HIS A 1 184 ? 4.11149   -3.52596  -28.58962 1.000 34.50051  ?  184 HIS A C   1 
ATOM   1239 O  O   . HIS A 1 184 ? 5.24783   -3.26349  -28.99292 1.000 36.55263  ?  184 HIS A O   1 
ATOM   1240 C  CB  . HIS A 1 184 ? 3.43529   -5.93242  -28.44046 1.000 40.13268  ?  184 HIS A CB  1 
ATOM   1241 C  CG  . HIS A 1 184 ? 4.47852   -6.44405  -29.38329 1.000 41.33720  ?  184 HIS A CG  1 
ATOM   1242 N  ND1 . HIS A 1 184 ? 5.57736   -7.15920  -28.95807 1.000 54.89495  ?  184 HIS A ND1 1 
ATOM   1243 C  CD2 . HIS A 1 184 ? 4.60178   -6.32805  -30.72656 1.000 35.50564  ?  184 HIS A CD2 1 
ATOM   1244 C  CE1 . HIS A 1 184 ? 6.32716   -7.47110  -29.99998 1.000 63.18577  ?  184 HIS A CE1 1 
ATOM   1245 N  NE2 . HIS A 1 184 ? 5.75764   -6.97836  -31.08516 1.000 68.35332  ?  184 HIS A NE2 1 
ATOM   1246 N  N   . TRP A 1 185 ? 3.04414   -2.81129  -28.95732 1.000 36.26840  ?  185 TRP A N   1 
ATOM   1247 C  CA  . TRP A 1 185 ? 3.20030   -1.60951  -29.77156 1.000 32.34816  ?  185 TRP A CA  1 
ATOM   1248 C  C   . TRP A 1 185 ? 3.96799   -0.53284  -29.02015 1.000 29.97056  ?  185 TRP A C   1 
ATOM   1249 O  O   . TRP A 1 185 ? 4.78470   0.18475   -29.60887 1.000 36.52501  ?  185 TRP A O   1 
ATOM   1250 C  CB  . TRP A 1 185 ? 1.83430   -1.07597  -30.20321 1.000 30.53266  ?  185 TRP A CB  1 
ATOM   1251 C  CG  . TRP A 1 185 ? 1.89965   0.31083   -30.77960 1.000 33.26024  ?  185 TRP A CG  1 
ATOM   1252 C  CD1 . TRP A 1 185 ? 2.10403   0.64567   -32.08618 1.000 34.61531  ?  185 TRP A CD1 1 
ATOM   1253 C  CD2 . TRP A 1 185 ? 1.76728   1.54849   -30.06514 1.000 36.45182  ?  185 TRP A CD2 1 
ATOM   1254 N  NE1 . TRP A 1 185 ? 2.10498   2.01220   -32.23088 1.000 34.81998  ?  185 TRP A NE1 1 
ATOM   1255 C  CE2 . TRP A 1 185 ? 1.90132   2.58934   -31.00505 1.000 36.27749  ?  185 TRP A CE2 1 
ATOM   1256 C  CE3 . TRP A 1 185 ? 1.54936   1.87615   -28.72299 1.000 34.86267  ?  185 TRP A CE3 1 
ATOM   1257 C  CZ2 . TRP A 1 185 ? 1.82268   3.93393   -30.64670 1.000 35.97417  ?  185 TRP A CZ2 1 
ATOM   1258 C  CZ3 . TRP A 1 185 ? 1.47236   3.21196   -28.36949 1.000 31.87219  ?  185 TRP A CZ3 1 
ATOM   1259 C  CH2 . TRP A 1 185 ? 1.60834   4.22359   -29.32753 1.000 31.80312  ?  185 TRP A CH2 1 
ATOM   1260 N  N   . LEU A 1 186 ? 3.70061   -0.39074  -27.72129 1.000 26.77799  ?  186 LEU A N   1 
ATOM   1261 C  CA  . LEU A 1 186 ? 4.42162   0.59028   -26.92083 1.000 26.43911  ?  186 LEU A CA  1 
ATOM   1262 C  C   . LEU A 1 186 ? 5.91728   0.30542   -26.93367 1.000 32.81562  ?  186 LEU A C   1 
ATOM   1263 O  O   . LEU A 1 186 ? 6.73336   1.23165   -27.00891 1.000 29.15427  ?  186 LEU A O   1 
ATOM   1264 C  CB  . LEU A 1 186 ? 3.87611   0.59457   -25.49304 1.000 24.22187  ?  186 LEU A CB  1 
ATOM   1265 C  CG  . LEU A 1 186 ? 4.15909   1.84381   -24.66316 1.000 23.90971  ?  186 LEU A CG  1 
ATOM   1266 C  CD1 . LEU A 1 186 ? 3.67315   3.07844   -25.40382 1.000 24.91345  ?  186 LEU A CD1 1 
ATOM   1267 C  CD2 . LEU A 1 186 ? 3.49637   1.73669   -23.29947 1.000 23.15262  ?  186 LEU A CD2 1 
ATOM   1268 N  N   . LYS A 1 187 ? 6.29543   -0.97460  -26.86821 1.000 36.76554  ?  187 LYS A N   1 
ATOM   1269 C  CA  . LYS A 1 187 ? 7.70666   -1.32318  -27.02017 1.000 25.67734  ?  187 LYS A CA  1 
ATOM   1270 C  C   . LYS A 1 187 ? 8.18402   -1.13481  -28.45757 1.000 29.38919  ?  187 LYS A C   1 
ATOM   1271 O  O   . LYS A 1 187 ? 9.35528   -0.80990  -28.68065 1.000 29.10218  ?  187 LYS A O   1 
ATOM   1272 C  CB  . LYS A 1 187 ? 7.96267   -2.76264  -26.57308 1.000 19.36251  ?  187 LYS A CB  1 
ATOM   1273 C  CG  . LYS A 1 187 ? 9.44290   -3.09618  -26.44461 1.000 25.97529  ?  187 LYS A CG  1 
ATOM   1274 C  CD  . LYS A 1 187 ? 9.69523   -4.59271  -26.42022 1.000 22.51942  ?  187 LYS A CD  1 
ATOM   1275 C  CE  . LYS A 1 187 ? 9.35945   -5.23179  -27.75484 1.000 28.00219  ?  187 LYS A CE  1 
ATOM   1276 N  NZ  . LYS A 1 187 ? 9.77389   -6.65881  -27.79433 1.000 25.01169  ?  187 LYS A NZ  1 
ATOM   1277 N  N   . SER A 1 188 ? 7.29598   -1.32908  -29.43835 1.000 28.93215  ?  188 SER A N   1 
ATOM   1278 C  CA  . SER A 1 188 ? 7.69480   -1.28291  -30.84290 1.000 26.72111  ?  188 SER A CA  1 
ATOM   1279 C  C   . SER A 1 188 ? 7.94301   0.14066   -31.31925 1.000 28.47341  ?  188 SER A C   1 
ATOM   1280 O  O   . SER A 1 188 ? 8.77435   0.35774   -32.20937 1.000 30.36347  ?  188 SER A O   1 
ATOM   1281 C  CB  . SER A 1 188 ? 6.62959   -1.94793  -31.71629 1.000 21.96614  ?  188 SER A CB  1 
ATOM   1282 O  OG  . SER A 1 188 ? 6.53678   -3.33301  -31.43807 1.000 44.75829  ?  188 SER A OG  1 
ATOM   1283 N  N   . ASN A 1 189 ? 7.23253   1.11145   -30.75440 1.000 27.04949  ?  189 ASN A N   1 
ATOM   1284 C  CA  . ASN A 1 189 ? 7.43146   2.51112   -31.08968 1.000 29.89819  ?  189 ASN A CA  1 
ATOM   1285 C  C   . ASN A 1 189 ? 8.57874   3.13549   -30.30145 1.000 28.89524  ?  189 ASN A C   1 
ATOM   1286 O  O   . ASN A 1 189 ? 8.94848   4.28485   -30.56853 1.000 23.57676  ?  189 ASN A O   1 
ATOM   1287 C  CB  . ASN A 1 189 ? 6.12639   3.28628   -30.85332 1.000 28.93397  ?  189 ASN A CB  1 
ATOM   1288 C  CG  . ASN A 1 189 ? 5.75353   4.18221   -32.01637 1.000 34.44000  ?  189 ASN A CG  1 
ATOM   1289 O  OD1 . ASN A 1 189 ? 6.15535   5.34457   -32.07946 1.000 81.26000  ?  189 ASN A OD1 1 
ATOM   1290 N  ND2 . ASN A 1 189 ? 4.97991   3.64091   -32.94355 1.000 34.99951  ?  189 ASN A ND2 1 
ATOM   1291 N  N   . ILE A 1 190 ? 9.17689   2.38837   -29.36968 1.000 23.26706  ?  190 ILE A N   1 
ATOM   1292 C  CA  . ILE A 1 190 ? 10.27878  2.88165   -28.56881 1.000 22.52003  ?  190 ILE A CA  1 
ATOM   1293 C  C   . ILE A 1 190 ? 11.58913  2.16670   -28.88486 1.000 23.53972  ?  190 ILE A C   1 
ATOM   1294 O  O   . ILE A 1 190 ? 12.65064  2.79973   -28.83953 1.000 22.37920  ?  190 ILE A O   1 
ATOM   1295 C  CB  . ILE A 1 190 ? 9.93342   2.75675   -27.06671 1.000 17.97914  ?  190 ILE A CB  1 
ATOM   1296 C  CG1 . ILE A 1 190 ? 8.79926   3.69513   -26.69044 1.000 19.11256  ?  190 ILE A CG1 1 
ATOM   1297 C  CG2 . ILE A 1 190 ? 11.16051  3.00064   -26.19466 1.000 22.37856  ?  190 ILE A CG2 1 
ATOM   1298 C  CD1 . ILE A 1 190 ? 8.37944   3.60027   -25.25743 1.000 11.22385  ?  190 ILE A CD1 1 
ATOM   1299 N  N   . SER A 1 191 ? 11.54191  0.89483   -29.26578 1.000 23.03702  ?  191 SER A N   1 
ATOM   1300 C  CA  . SER A 1 191 ? 12.74756  0.11263   -29.48285 1.000 17.97766  ?  191 SER A CA  1 
ATOM   1301 C  C   . SER A 1 191 ? 13.36082  0.40999   -30.84623 1.000 20.56864  ?  191 SER A C   1 
ATOM   1302 O  O   . SER A 1 191 ? 12.65905  0.68041   -31.82506 1.000 26.20481  ?  191 SER A O   1 
ATOM   1303 C  CB  . SER A 1 191 ? 12.44418  -1.38595  -29.36323 1.000 19.92692  ?  191 SER A CB  1 
ATOM   1304 O  OG  . SER A 1 191 ? 13.58763  -2.18117  -29.63674 1.000 21.06575  ?  191 SER A OG  1 
ATOM   1305 N  N   . LEU A 1 192 ? 14.69330  0.33692   -30.90432 1.000 14.01731  ?  192 LEU A N   1 
ATOM   1306 C  CA  . LEU A 1 192 ? 15.41623  0.48877   -32.16240 1.000 16.10446  ?  192 LEU A CA  1 
ATOM   1307 C  C   . LEU A 1 192 ? 15.45576  -0.79217  -32.98902 1.000 18.01663  ?  192 LEU A C   1 
ATOM   1308 O  O   . LEU A 1 192 ? 15.78688  -0.73575  -34.18078 1.000 19.37013  ?  192 LEU A O   1 
ATOM   1309 C  CB  . LEU A 1 192 ? 16.85331  0.95987   -31.90571 1.000 18.10113  ?  192 LEU A CB  1 
ATOM   1310 C  CG  . LEU A 1 192 ? 17.11016  2.46606   -31.78757 1.000 17.79023  ?  192 LEU A CG  1 
ATOM   1311 C  CD1 . LEU A 1 192 ? 16.51091  3.03947   -30.51299 1.000 17.82830  ?  192 LEU A CD1 1 
ATOM   1312 C  CD2 . LEU A 1 192 ? 18.60251  2.74330   -31.85896 1.000 13.16662  ?  192 LEU A CD2 1 
ATOM   1313 N  N   . LEU A 1 193 ? 15.12315  -1.93726  -32.39810 1.000 18.87761  ?  193 LEU A N   1 
ATOM   1314 C  CA  . LEU A 1 193 ? 15.21031  -3.21788  -33.08349 1.000 22.43246  ?  193 LEU A CA  1 
ATOM   1315 C  C   . LEU A 1 193 ? 13.87131  -3.68050  -33.64428 1.000 20.57847  ?  193 LEU A C   1 
ATOM   1316 O  O   . LEU A 1 193 ? 13.76416  -4.82520  -34.09514 1.000 22.86105  ?  193 LEU A O   1 
ATOM   1317 C  CB  . LEU A 1 193 ? 15.78357  -4.28235  -32.14460 1.000 18.62936  ?  193 LEU A CB  1 
ATOM   1318 C  CG  . LEU A 1 193 ? 16.58236  -5.38811  -32.84190 1.000 14.48583  ?  193 LEU A CG  1 
ATOM   1319 C  CD1 . LEU A 1 193 ? 17.77821  -4.79425  -33.56990 1.000 21.48818  ?  193 LEU A CD1 1 
ATOM   1320 C  CD2 . LEU A 1 193 ? 17.02545  -6.45269  -31.85603 1.000 18.32584  ?  193 LEU A CD2 1 
ATOM   1321 N  N   . THR A 1 194 ? 12.84955  -2.82099  -33.62880 1.000 16.61362  ?  194 THR A N   1 
ATOM   1322 C  CA  . THR A 1 194 ? 11.57435  -3.18726  -34.23704 1.000 16.96044  ?  194 THR A CA  1 
ATOM   1323 C  C   . THR A 1 194 ? 11.74303  -3.46474  -35.72544 1.000 17.31169  ?  194 THR A C   1 
ATOM   1324 O  O   . THR A 1 194 ? 11.16441  -4.41852  -36.25925 1.000 20.66781  ?  194 THR A O   1 
ATOM   1325 C  CB  . THR A 1 194 ? 10.54625  -2.08173  -34.00438 1.000 18.02569  ?  194 THR A CB  1 
ATOM   1326 O  OG1 . THR A 1 194 ? 10.43665  -1.82492  -32.59898 1.000 22.53662  ?  194 THR A OG1 1 
ATOM   1327 C  CG2 . THR A 1 194 ? 9.18648   -2.49630  -34.54417 1.000 18.37429  ?  194 THR A CG2 1 
ATOM   1328 N  N   . THR A 1 195 ? 12.53442  -2.64536  -36.40746 1.000 18.29929  ?  195 THR A N   1 
ATOM   1329 C  CA  . THR A 1 195 ? 12.96389  -2.89504  -37.77362 1.000 14.82954  ?  195 THR A CA  1 
ATOM   1330 C  C   . THR A 1 195 ? 14.48593  -2.94462  -37.81015 1.000 17.98729  ?  195 THR A C   1 
ATOM   1331 O  O   . THR A 1 195 ? 15.16290  -2.62433  -36.82969 1.000 17.49781  ?  195 THR A O   1 
ATOM   1332 C  CB  . THR A 1 195 ? 12.43913  -1.81721  -38.72957 1.000 9.50588   ?  195 THR A CB  1 
ATOM   1333 O  OG1 . THR A 1 195 ? 12.84464  -0.52412  -38.26309 1.000 10.93370  ?  195 THR A OG1 1 
ATOM   1334 C  CG2 . THR A 1 195 ? 10.92401  -1.86864  -38.80964 1.000 13.91005  ?  195 THR A CG2 1 
ATOM   1335 N  N   . ASP A 1 196 ? 15.02560  -3.35422  -38.94907 1.000 15.31089  ?  196 ASP A N   1 
ATOM   1336 C  CA  . ASP A 1 196 ? 16.47497  -3.41044  -39.09655 1.000 14.29954  ?  196 ASP A CA  1 
ATOM   1337 C  C   . ASP A 1 196 ? 17.02339  -1.99305  -39.18998 1.000 16.18830  ?  196 ASP A C   1 
ATOM   1338 O  O   . ASP A 1 196 ? 16.69305  -1.27432  -40.14212 1.000 15.08081  ?  196 ASP A O   1 
ATOM   1339 C  CB  . ASP A 1 196 ? 16.85493  -4.21641  -40.33645 1.000 15.72432  ?  196 ASP A CB  1 
ATOM   1340 C  CG  . ASP A 1 196 ? 18.33327  -4.56031  -40.38185 1.000 19.15906  ?  196 ASP A CG  1 
ATOM   1341 O  OD1 . ASP A 1 196 ? 19.07703  -4.12654  -39.47837 1.000 20.73439  ?  196 ASP A OD1 1 
ATOM   1342 O  OD2 . ASP A 1 196 ? 18.75275  -5.26969  -41.32071 1.000 18.28813  -1 196 ASP A OD2 1 
ATOM   1343 N  N   . PRO A 1 197 ? 17.84995  -1.54844  -38.23976 1.000 19.76433  ?  197 PRO A N   1 
ATOM   1344 C  CA  . PRO A 1 197 ? 18.38248  -0.17875  -38.32052 1.000 22.87942  ?  197 PRO A CA  1 
ATOM   1345 C  C   . PRO A 1 197 ? 19.21260  0.07213   -39.56387 1.000 23.21048  ?  197 PRO A C   1 
ATOM   1346 O  O   . PRO A 1 197 ? 19.21663  1.19813   -40.07753 1.000 29.56881  ?  197 PRO A O   1 
ATOM   1347 C  CB  . PRO A 1 197 ? 19.22544  -0.05530  -37.04275 1.000 25.10302  ?  197 PRO A CB  1 
ATOM   1348 C  CG  . PRO A 1 197 ? 18.67015  -1.09145  -36.11824 1.000 29.90774  ?  197 PRO A CG  1 
ATOM   1349 C  CD  . PRO A 1 197 ? 18.26564  -2.23019  -37.00322 1.000 23.39099  ?  197 PRO A CD  1 
ATOM   1350 N  N   . LEU A 1 198 ? 19.91556  -0.94509  -40.06840 1.000 16.19022  ?  198 LEU A N   1 
ATOM   1351 C  CA  . LEU A 1 198 ? 20.72969  -0.76200  -41.26349 1.000 18.77525  ?  198 LEU A CA  1 
ATOM   1352 C  C   . LEU A 1 198 ? 19.88560  -0.50786  -42.50559 1.000 22.82186  ?  198 LEU A C   1 
ATOM   1353 O  O   . LEU A 1 198 ? 20.42095  -0.04707  -43.51935 1.000 24.25034  ?  198 LEU A O   1 
ATOM   1354 C  CB  . LEU A 1 198 ? 21.62585  -1.98112  -41.49098 1.000 14.58810  ?  198 LEU A CB  1 
ATOM   1355 C  CG  . LEU A 1 198 ? 22.53979  -2.43948  -40.35191 1.000 13.97771  ?  198 LEU A CG  1 
ATOM   1356 C  CD1 . LEU A 1 198 ? 23.62951  -3.35431  -40.88899 1.000 20.72284  ?  198 LEU A CD1 1 
ATOM   1357 C  CD2 . LEU A 1 198 ? 23.14801  -1.26393  -39.61252 1.000 21.26585  ?  198 LEU A CD2 1 
ATOM   1358 N  N   . VAL A 1 199 ? 18.58793  -0.79171  -42.45109 1.000 19.13377  ?  199 VAL A N   1 
ATOM   1359 C  CA  . VAL A 1 199 ? 17.68793  -0.61684  -43.58297 1.000 17.19872  ?  199 VAL A CA  1 
ATOM   1360 C  C   . VAL A 1 199 ? 16.75833  0.57500   -43.37653 1.000 21.36465  ?  199 VAL A C   1 
ATOM   1361 O  O   . VAL A 1 199 ? 16.62096  1.42562   -44.25643 1.000 24.09783  ?  199 VAL A O   1 
ATOM   1362 C  CB  . VAL A 1 199 ? 16.88209  -1.90777  -43.84972 1.000 9.89807   ?  199 VAL A CB  1 
ATOM   1363 C  CG1 . VAL A 1 199 ? 16.09357  -1.78386  -45.14431 1.000 8.04618   ?  199 VAL A CG1 1 
ATOM   1364 C  CG2 . VAL A 1 199 ? 17.80893  -3.10944  -43.89053 1.000 12.92348  ?  199 VAL A CG2 1 
ATOM   1365 N  N   . THR A 1 200 ? 16.10952  0.65047   -42.21167 1.000 17.52167  ?  200 THR A N   1 
ATOM   1366 C  CA  . THR A 1 200 ? 15.16469  1.73307   -41.95549 1.000 16.87977  ?  200 THR A CA  1 
ATOM   1367 C  C   . THR A 1 200 ? 15.87261  3.07310   -41.79096 1.000 17.43560  ?  200 THR A C   1 
ATOM   1368 O  O   . THR A 1 200 ? 15.31948  4.11597   -42.16016 1.000 14.30172  ?  200 THR A O   1 
ATOM   1369 C  CB  . THR A 1 200 ? 14.32414  1.40585   -40.71945 1.000 18.21920  ?  200 THR A CB  1 
ATOM   1370 O  OG1 . THR A 1 200 ? 13.64949  0.15902   -40.92542 1.000 12.39893  ?  200 THR A OG1 1 
ATOM   1371 C  CG2 . THR A 1 200 ? 13.28599  2.49062   -40.46157 1.000 23.08203  ?  200 THR A CG2 1 
ATOM   1372 N  N   . TYR A 1 201 ? 17.09185  3.06821   -41.25939 1.000 20.97123  ?  201 TYR A N   1 
ATOM   1373 C  CA  . TYR A 1 201 ? 17.89896  4.27795   -41.10436 1.000 17.67295  ?  201 TYR A CA  1 
ATOM   1374 C  C   . TYR A 1 201 ? 19.26957  4.02214   -41.71612 1.000 17.43369  ?  201 TYR A C   1 
ATOM   1375 O  O   . TYR A 1 201 ? 20.26157  3.82656   -41.00370 1.000 15.91071  ?  201 TYR A O   1 
ATOM   1376 C  CB  . TYR A 1 201 ? 17.99898  4.67904   -39.63299 1.000 13.32662  ?  201 TYR A CB  1 
ATOM   1377 C  CG  . TYR A 1 201 ? 16.65023  4.72036   -38.95701 1.000 16.27827  ?  201 TYR A CG  1 
ATOM   1378 C  CD1 . TYR A 1 201 ? 15.77261  5.77128   -39.18377 1.000 20.82088  ?  201 TYR A CD1 1 
ATOM   1379 C  CD2 . TYR A 1 201 ? 16.24452  3.69955   -38.10926 1.000 19.92195  ?  201 TYR A CD2 1 
ATOM   1380 C  CE1 . TYR A 1 201 ? 14.53276  5.81093   -38.57700 1.000 14.82942  ?  201 TYR A CE1 1 
ATOM   1381 C  CE2 . TYR A 1 201 ? 15.00597  3.73080   -37.49674 1.000 21.94152  ?  201 TYR A CE2 1 
ATOM   1382 C  CZ  . TYR A 1 201 ? 14.15483  4.78897   -37.73438 1.000 14.64486  ?  201 TYR A CZ  1 
ATOM   1383 O  OH  . TYR A 1 201 ? 12.92068  4.82442   -37.12771 1.000 20.20822  ?  201 TYR A OH  1 
ATOM   1384 N  N   . PRO A 1 202 ? 19.35808  4.01661   -43.06210 1.000 19.06221  ?  202 PRO A N   1 
ATOM   1385 C  CA  . PRO A 1 202 ? 20.58158  3.61120   -43.76569 1.000 22.07749  ?  202 PRO A CA  1 
ATOM   1386 C  C   . PRO A 1 202 ? 21.61855  4.72479   -43.90267 1.000 21.28843  ?  202 PRO A C   1 
ATOM   1387 O  O   . PRO A 1 202 ? 22.19223  4.93714   -44.97240 1.000 20.85492  ?  202 PRO A O   1 
ATOM   1388 C  CB  . PRO A 1 202 ? 20.04807  3.17033   -45.13149 1.000 25.41914  ?  202 PRO A CB  1 
ATOM   1389 C  CG  . PRO A 1 202 ? 18.88797  4.08626   -45.36174 1.000 22.55449  ?  202 PRO A CG  1 
ATOM   1390 C  CD  . PRO A 1 202 ? 18.27620  4.36112   -44.00302 1.000 19.51345  ?  202 PRO A CD  1 
ATOM   1391 N  N   . SER A 1 203 ? 21.86038  5.44101   -42.80854 1.000 25.48932  ?  203 SER A N   1 
ATOM   1392 C  CA  . SER A 1 203 ? 22.92216  6.43490   -42.76696 1.000 28.77438  ?  203 SER A CA  1 
ATOM   1393 C  C   . SER A 1 203 ? 23.26695  6.70813   -41.31217 1.000 32.77552  ?  203 SER A C   1 
ATOM   1394 O  O   . SER A 1 203 ? 22.43291  6.53468   -40.41912 1.000 28.49181  ?  203 SER A O   1 
ATOM   1395 C  CB  . SER A 1 203 ? 22.52542  7.73623   -43.47510 1.000 23.03566  ?  203 SER A CB  1 
ATOM   1396 O  OG  . SER A 1 203 ? 22.00364  8.67855   -42.55644 1.000 18.05492  ?  203 SER A OG  1 
ATOM   1397 N  N   . LEU A 1 204 ? 24.51262  7.13133   -41.09112 1.000 32.44009  ?  204 LEU A N   1 
ATOM   1398 C  CA  . LEU A 1 204 ? 24.95744  7.48759   -39.74816 1.000 26.02224  ?  204 LEU A CA  1 
ATOM   1399 C  C   . LEU A 1 204 ? 24.07123  8.57402   -39.14912 1.000 32.38205  ?  204 LEU A C   1 
ATOM   1400 O  O   . LEU A 1 204 ? 23.65486  8.48312   -37.98492 1.000 33.77020  ?  204 LEU A O   1 
ATOM   1401 C  CB  . LEU A 1 204 ? 26.41991  7.93296   -39.81087 1.000 21.39819  ?  204 LEU A CB  1 
ATOM   1402 C  CG  . LEU A 1 204 ? 27.09309  8.68288   -38.66342 1.000 26.53668  ?  204 LEU A CG  1 
ATOM   1403 C  CD1 . LEU A 1 204 ? 27.11986  7.84248   -37.41231 1.000 31.22954  ?  204 LEU A CD1 1 
ATOM   1404 C  CD2 . LEU A 1 204 ? 28.50642  9.07275   -39.06851 1.000 33.95786  ?  204 LEU A CD2 1 
ATOM   1405 N  N   . ASP A 1 205 ? 23.74726  9.59420   -39.94601 1.000 38.36182  ?  205 ASP A N   1 
ATOM   1406 C  CA  . ASP A 1 205 ? 22.89954  10.68242  -39.47193 1.000 35.79174  ?  205 ASP A CA  1 
ATOM   1407 C  C   . ASP A 1 205 ? 21.50662  10.18454  -39.09965 1.000 33.54210  ?  205 ASP A C   1 
ATOM   1408 O  O   . ASP A 1 205 ? 20.96677  10.55155  -38.05024 1.000 31.58982  ?  205 ASP A O   1 
ATOM   1409 C  CB  . ASP A 1 205 ? 22.81973  11.77356  -40.54061 1.000 42.18638  ?  205 ASP A CB  1 
ATOM   1410 C  CG  . ASP A 1 205 ? 21.68358  12.74584  -40.29922 1.000 61.73570  ?  205 ASP A CG  1 
ATOM   1411 O  OD1 . ASP A 1 205 ? 21.58160  13.27672  -39.17303 1.000 79.35532  ?  205 ASP A OD1 1 
ATOM   1412 O  OD2 . ASP A 1 205 ? 20.89692  12.98510  -41.24053 1.000 58.37667  -1 205 ASP A OD2 1 
ATOM   1413 N  N   . LYS A 1 206 ? 20.90722  9.34410   -39.94903 1.000 27.69726  ?  206 LYS A N   1 
ATOM   1414 C  CA  . LYS A 1 206 ? 19.54699  8.87563   -39.68961 1.000 26.22488  ?  206 LYS A CA  1 
ATOM   1415 C  C   . LYS A 1 206 ? 19.48189  8.00275   -38.44045 1.000 26.21035  ?  206 LYS A C   1 
ATOM   1416 O  O   . LYS A 1 206 ? 18.56766  8.14949   -37.61691 1.000 20.70301  ?  206 LYS A O   1 
ATOM   1417 C  CB  . LYS A 1 206 ? 19.01352  8.11321   -40.90284 1.000 19.42142  ?  206 LYS A CB  1 
ATOM   1418 C  CG  . LYS A 1 206 ? 18.90726  8.94488   -42.17113 1.000 15.94784  ?  206 LYS A CG  1 
ATOM   1419 C  CD  . LYS A 1 206 ? 18.58982  8.06850   -43.37080 1.000 16.78526  ?  206 LYS A CD  1 
ATOM   1420 C  CE  . LYS A 1 206 ? 18.71218  8.83984   -44.67468 1.000 12.44876  ?  206 LYS A CE  1 
ATOM   1421 N  NZ  . LYS A 1 206 ? 18.47822  7.96096   -45.85475 1.000 13.84175  ?  206 LYS A NZ  1 
ATOM   1422 N  N   . VAL A 1 207 ? 20.43980  7.08742   -38.27967 1.000 26.81875  ?  207 VAL A N   1 
ATOM   1423 C  CA  . VAL A 1 207 ? 20.41632  6.20912   -37.11543 1.000 22.83811  ?  207 VAL A CA  1 
ATOM   1424 C  C   . VAL A 1 207 ? 20.70373  6.99902   -35.84316 1.000 24.33797  ?  207 VAL A C   1 
ATOM   1425 O  O   . VAL A 1 207 ? 20.13249  6.71664   -34.78287 1.000 25.13262  ?  207 VAL A O   1 
ATOM   1426 C  CB  . VAL A 1 207 ? 21.38705  5.02629   -37.30014 1.000 18.92210  ?  207 VAL A CB  1 
ATOM   1427 C  CG1 . VAL A 1 207 ? 22.83234  5.49468   -37.35873 1.000 17.22522  ?  207 VAL A CG1 1 
ATOM   1428 C  CG2 . VAL A 1 207 ? 21.18855  4.00610   -36.18962 1.000 14.11231  ?  207 VAL A CG2 1 
ATOM   1429 N  N   . TRP A 1 208 ? 21.57676  8.00983   -35.92029 1.000 23.94010  ?  208 TRP A N   1 
ATOM   1430 C  CA  . TRP A 1 208 ? 21.78844  8.84849   -34.74439 1.000 21.08053  ?  208 TRP A CA  1 
ATOM   1431 C  C   . TRP A 1 208 ? 20.55412  9.68024   -34.41805 1.000 26.69278  ?  208 TRP A C   1 
ATOM   1432 O  O   . TRP A 1 208 ? 20.26330  9.92298   -33.23829 1.000 26.27869  ?  208 TRP A O   1 
ATOM   1433 C  CB  . TRP A 1 208 ? 23.01065  9.74049   -34.93865 1.000 18.42343  ?  208 TRP A CB  1 
ATOM   1434 C  CG  . TRP A 1 208 ? 24.18314  9.24354   -34.16451 1.000 19.73044  ?  208 TRP A CG  1 
ATOM   1435 C  CD1 . TRP A 1 208 ? 25.26734  8.57668   -34.65250 1.000 18.18788  ?  208 TRP A CD1 1 
ATOM   1436 C  CD2 . TRP A 1 208 ? 24.37541  9.34311   -32.74939 1.000 22.17039  ?  208 TRP A CD2 1 
ATOM   1437 N  NE1 . TRP A 1 208 ? 26.13278  8.26783   -33.63058 1.000 18.30522  ?  208 TRP A NE1 1 
ATOM   1438 C  CE2 . TRP A 1 208 ? 25.60754  8.72776   -32.45132 1.000 25.05292  ?  208 TRP A CE2 1 
ATOM   1439 C  CE3 . TRP A 1 208 ? 23.62987  9.90202   -31.70641 1.000 19.45996  ?  208 TRP A CE3 1 
ATOM   1440 C  CZ2 . TRP A 1 208 ? 26.11078  8.65472   -31.15343 1.000 24.75014  ?  208 TRP A CZ2 1 
ATOM   1441 C  CZ3 . TRP A 1 208 ? 24.13038  9.82771   -30.41862 1.000 21.41668  ?  208 TRP A CZ3 1 
ATOM   1442 C  CH2 . TRP A 1 208 ? 25.35861  9.20834   -30.15338 1.000 22.37372  ?  208 TRP A CH2 1 
ATOM   1443 N  N   . GLY A 1 209 ? 19.81908  10.12084  -35.44052 1.000 22.04360  ?  209 GLY A N   1 
ATOM   1444 C  CA  . GLY A 1 209 ? 18.54576  10.77195  -35.19080 1.000 17.05834  ?  209 GLY A CA  1 
ATOM   1445 C  C   . GLY A 1 209 ? 17.56603  9.85642   -34.48544 1.000 19.35260  ?  209 GLY A C   1 
ATOM   1446 O  O   . GLY A 1 209 ? 16.87457  10.27181  -33.55448 1.000 23.69717  ?  209 GLY A O   1 
ATOM   1447 N  N   . ARG A 1 210 ? 17.50591  8.59187   -34.91026 1.000 18.56318  ?  210 ARG A N   1 
ATOM   1448 C  CA  . ARG A 1 210 ? 16.64100  7.62695   -34.23312 1.000 20.64840  ?  210 ARG A CA  1 
ATOM   1449 C  C   . ARG A 1 210 ? 17.08202  7.40236   -32.78893 1.000 22.25992  ?  210 ARG A C   1 
ATOM   1450 O  O   . ARG A 1 210 ? 16.24586  7.25888   -31.89076 1.000 25.60299  ?  210 ARG A O   1 
ATOM   1451 C  CB  . ARG A 1 210 ? 16.62087  6.30317   -34.99702 1.000 16.66723  ?  210 ARG A CB  1 
ATOM   1452 C  CG  . ARG A 1 210 ? 15.73114  5.24396   -34.36072 1.000 15.14794  ?  210 ARG A CG  1 
ATOM   1453 C  CD  . ARG A 1 210 ? 14.28703  5.71843   -34.27698 1.000 16.54501  ?  210 ARG A CD  1 
ATOM   1454 N  NE  . ARG A 1 210 ? 13.44916  4.80904   -33.50385 1.000 16.75580  ?  210 ARG A NE  1 
ATOM   1455 C  CZ  . ARG A 1 210 ? 13.12299  4.98948   -32.23085 1.000 19.40501  ?  210 ARG A CZ  1 
ATOM   1456 N  NH1 . ARG A 1 210 ? 13.54149  6.04566   -31.55282 1.000 17.15810  ?  210 ARG A NH1 1 
ATOM   1457 N  NH2 . ARG A 1 210 ? 12.35428  4.08941   -31.62366 1.000 20.22487  ?  210 ARG A NH2 1 
ATOM   1458 N  N   . PHE A 1 211 ? 18.39399  7.35865   -32.55149 1.000 25.32268  ?  211 PHE A N   1 
ATOM   1459 C  CA  . PHE A 1 211 ? 18.91976  7.17293   -31.19910 1.000 26.74904  ?  211 PHE A CA  1 
ATOM   1460 C  C   . PHE A 1 211 ? 18.51852  8.33126   -30.28556 1.000 25.05867  ?  211 PHE A C   1 
ATOM   1461 O  O   . PHE A 1 211 ? 18.00894  8.12690   -29.16965 1.000 19.95758  ?  211 PHE A O   1 
ATOM   1462 C  CB  . PHE A 1 211 ? 20.44272  7.03744   -31.28079 1.000 20.43941  ?  211 PHE A CB  1 
ATOM   1463 C  CG  . PHE A 1 211 ? 21.06844  6.33848   -30.11067 1.000 13.67540  ?  211 PHE A CG  1 
ATOM   1464 C  CD1 . PHE A 1 211 ? 20.54096  5.15601   -29.62423 1.000 15.78341  ?  211 PHE A CD1 1 
ATOM   1465 C  CD2 . PHE A 1 211 ? 22.21536  6.84688   -29.52462 1.000 18.11598  ?  211 PHE A CD2 1 
ATOM   1466 C  CE1 . PHE A 1 211 ? 21.12890  4.50865   -28.55506 1.000 18.52926  ?  211 PHE A CE1 1 
ATOM   1467 C  CE2 . PHE A 1 211 ? 22.81065  6.20404   -28.45966 1.000 23.99170  ?  211 PHE A CE2 1 
ATOM   1468 C  CZ  . PHE A 1 211 ? 22.26647  5.03250   -27.97317 1.000 29.87926  ?  211 PHE A CZ  1 
ATOM   1469 N  N   . ASP A 1 212 ? 18.73817  9.56361   -30.75266 1.000 22.77365  ?  212 ASP A N   1 
ATOM   1470 C  CA  . ASP A 1 212 ? 18.33526  10.73178  -29.97767 1.000 22.80625  ?  212 ASP A CA  1 
ATOM   1471 C  C   . ASP A 1 212 ? 16.82439  10.78487  -29.79456 1.000 21.91687  ?  212 ASP A C   1 
ATOM   1472 O  O   . ASP A 1 212 ? 16.34273  11.22432  -28.74405 1.000 22.74173  ?  212 ASP A O   1 
ATOM   1473 C  CB  . ASP A 1 212 ? 18.84442  12.00763  -30.64845 1.000 30.23005  ?  212 ASP A CB  1 
ATOM   1474 C  CG  . ASP A 1 212 ? 20.34436  12.18543  -30.49892 1.000 30.06121  ?  212 ASP A CG  1 
ATOM   1475 O  OD1 . ASP A 1 212 ? 20.85231  12.04525  -29.36510 1.000 25.77232  ?  212 ASP A OD1 1 
ATOM   1476 O  OD2 . ASP A 1 212 ? 21.01586  12.45939  -31.51592 1.000 26.32888  -1 212 ASP A OD2 1 
ATOM   1477 N  N   . LYS A 1 213 ? 16.06256  10.34090  -30.79851 1.000 19.78927  ?  213 LYS A N   1 
ATOM   1478 C  CA  . LYS A 1 213 ? 14.61327  10.26587  -30.65416 1.000 21.17190  ?  213 LYS A CA  1 
ATOM   1479 C  C   . LYS A 1 213 ? 14.22064  9.27784   -29.56486 1.000 23.83914  ?  213 LYS A C   1 
ATOM   1480 O  O   . LYS A 1 213 ? 13.30473  9.54111   -28.78337 1.000 29.96187  ?  213 LYS A O   1 
ATOM   1481 C  CB  . LYS A 1 213 ? 13.97312  9.87993   -31.98792 1.000 19.29720  ?  213 LYS A CB  1 
ATOM   1482 C  CG  . LYS A 1 213 ? 12.48926  9.55338   -31.89831 1.000 23.85306  ?  213 LYS A CG  1 
ATOM   1483 C  CD  . LYS A 1 213 ? 11.67193  10.75306  -31.44348 1.000 22.61118  ?  213 LYS A CD  1 
ATOM   1484 C  CE  . LYS A 1 213 ? 11.66509  11.85084  -32.49361 1.000 30.52790  ?  213 LYS A CE  1 
ATOM   1485 N  NZ  . LYS A 1 213 ? 10.80430  12.99672  -32.08825 1.000 33.47084  ?  213 LYS A NZ  1 
ATOM   1486 N  N   . HIS A 1 214 ? 14.89834  8.13144   -29.50647 1.000 24.98594  ?  214 HIS A N   1 
ATOM   1487 C  CA  . HIS A 1 214 ? 14.65565  7.16045   -28.44251 1.000 23.03277  ?  214 HIS A CA  1 
ATOM   1488 C  C   . HIS A 1 214 ? 14.88154  7.78868   -27.07279 1.000 23.88163  ?  214 HIS A C   1 
ATOM   1489 O  O   . HIS A 1 214 ? 14.05354  7.65167   -26.15549 1.000 25.11214  ?  214 HIS A O   1 
ATOM   1490 C  CB  . HIS A 1 214 ? 15.57516  5.95444   -28.64942 1.000 23.17042  ?  214 HIS A CB  1 
ATOM   1491 C  CG  . HIS A 1 214 ? 15.55991  4.96548   -27.52602 1.000 21.56273  ?  214 HIS A CG  1 
ATOM   1492 N  ND1 . HIS A 1 214 ? 14.46398  4.18182   -27.23843 1.000 25.73883  ?  214 HIS A ND1 1 
ATOM   1493 C  CD2 . HIS A 1 214 ? 16.51668  4.61534   -26.63393 1.000 19.47097  ?  214 HIS A CD2 1 
ATOM   1494 C  CE1 . HIS A 1 214 ? 14.74214  3.39736   -26.21283 1.000 26.53766  ?  214 HIS A CE1 1 
ATOM   1495 N  NE2 . HIS A 1 214 ? 15.98087  3.64245   -25.82538 1.000 27.56581  ?  214 HIS A NE2 1 
ATOM   1496 N  N   . PHE A 1 215 ? 16.00146  8.49850   -26.92343 1.000 24.00380  ?  215 PHE A N   1 
ATOM   1497 C  CA  . PHE A 1 215 ? 16.29091  9.12712   -25.63750 1.000 24.89962  ?  215 PHE A CA  1 
ATOM   1498 C  C   . PHE A 1 215 ? 15.26129  10.19821  -25.29207 1.000 29.93773  ?  215 PHE A C   1 
ATOM   1499 O  O   . PHE A 1 215 ? 14.84112  10.30991  -24.13480 1.000 31.36101  ?  215 PHE A O   1 
ATOM   1500 C  CB  . PHE A 1 215 ? 17.70371  9.70353   -25.63211 1.000 27.87531  ?  215 PHE A CB  1 
ATOM   1501 C  CG  . PHE A 1 215 ? 18.76339  8.67348   -25.39448 1.000 26.13832  ?  215 PHE A CG  1 
ATOM   1502 C  CD1 . PHE A 1 215 ? 18.89296  8.07213   -24.15325 1.000 26.74721  ?  215 PHE A CD1 1 
ATOM   1503 C  CD2 . PHE A 1 215 ? 19.62095  8.29575   -26.40998 1.000 25.14802  ?  215 PHE A CD2 1 
ATOM   1504 C  CE1 . PHE A 1 215 ? 19.86251  7.11616   -23.92917 1.000 27.83944  ?  215 PHE A CE1 1 
ATOM   1505 C  CE2 . PHE A 1 215 ? 20.59186  7.34364   -26.19106 1.000 27.52175  ?  215 PHE A CE2 1 
ATOM   1506 C  CZ  . PHE A 1 215 ? 20.71380  6.75158   -24.95009 1.000 28.89367  ?  215 PHE A CZ  1 
ATOM   1507 N  N   . SER A 1 216 ? 14.84234  10.99744  -26.27705 1.000 24.63197  ?  216 SER A N   1 
ATOM   1508 C  CA  . SER A 1 216 ? 13.82480  12.00951  -26.00798 1.000 22.07796  ?  216 SER A CA  1 
ATOM   1509 C  C   . SER A 1 216 ? 12.47915  11.37481  -25.68049 1.000 25.81867  ?  216 SER A C   1 
ATOM   1510 O  O   . SER A 1 216 ? 11.69402  11.94798  -24.91637 1.000 32.67348  ?  216 SER A O   1 
ATOM   1511 C  CB  . SER A 1 216 ? 13.68909  12.95910  -27.19789 1.000 22.85417  ?  216 SER A CB  1 
ATOM   1512 O  OG  . SER A 1 216 ? 13.10345  12.30775  -28.31000 1.000 27.01050  ?  216 SER A OG  1 
ATOM   1513 N  N   . GLN A 1 217 ? 12.19405  10.20389  -26.25607 1.000 23.45353  ?  217 GLN A N   1 
ATOM   1514 C  CA  . GLN A 1 217 ? 10.97305  9.48017   -25.91997 1.000 25.88287  ?  217 GLN A CA  1 
ATOM   1515 C  C   . GLN A 1 217 ? 10.98113  9.03847   -24.46607 1.000 29.32809  ?  217 GLN A C   1 
ATOM   1516 O  O   . GLN A 1 217 ? 9.96676   9.15167   -23.76733 1.000 28.10639  ?  217 GLN A O   1 
ATOM   1517 C  CB  . GLN A 1 217 ? 10.80937  8.26215   -26.83041 1.000 22.95821  ?  217 GLN A CB  1 
ATOM   1518 C  CG  . GLN A 1 217 ? 10.47224  8.57199   -28.27415 1.000 26.27557  ?  217 GLN A CG  1 
ATOM   1519 C  CD  . GLN A 1 217 ? 10.46049  7.32590   -29.13935 1.000 19.67052  ?  217 GLN A CD  1 
ATOM   1520 O  OE1 . GLN A 1 217 ? 11.49089  6.68025   -29.33169 1.000 15.95321  ?  217 GLN A OE1 1 
ATOM   1521 N  NE2 . GLN A 1 217 ? 9.28973   6.97638   -29.65812 1.000 22.81321  ?  217 GLN A NE2 1 
ATOM   1522 N  N   . LEU A 1 218 ? 12.11379  8.52105   -23.99446 1.000 32.93001  ?  218 LEU A N   1 
ATOM   1523 C  CA  . LEU A 1 218 ? 12.16249  7.98935   -22.63594 1.000 33.21550  ?  218 LEU A CA  1 
ATOM   1524 C  C   . LEU A 1 218 ? 12.52674  9.02749   -21.57716 1.000 34.89275  ?  218 LEU A C   1 
ATOM   1525 O  O   . LEU A 1 218 ? 12.44332  8.71744   -20.38197 1.000 30.00286  ?  218 LEU A O   1 
ATOM   1526 C  CB  . LEU A 1 218 ? 13.14950  6.82056   -22.55937 1.000 32.33964  ?  218 LEU A CB  1 
ATOM   1527 C  CG  . LEU A 1 218 ? 12.72762  5.54842   -23.29533 1.000 23.06034  ?  218 LEU A CG  1 
ATOM   1528 C  CD1 . LEU A 1 218 ? 13.78764  4.47828   -23.13393 1.000 24.21020  ?  218 LEU A CD1 1 
ATOM   1529 C  CD2 . LEU A 1 218 ? 11.38111  5.05205   -22.78972 1.000 21.24982  ?  218 LEU A CD2 1 
ATOM   1530 N  N   . ARG A 1 219 ? 12.91564  10.24180  -21.97988 1.000 33.31478  ?  219 ARG A N   1 
ATOM   1531 C  CA  . ARG A 1 219 ? 13.38526  11.23826  -21.01835 1.000 26.62472  ?  219 ARG A CA  1 
ATOM   1532 C  C   . ARG A 1 219 ? 12.31173  11.59330  -19.99584 1.000 27.27464  ?  219 ARG A C   1 
ATOM   1533 O  O   . ARG A 1 219 ? 12.58691  11.66416  -18.79211 1.000 27.74447  ?  219 ARG A O   1 
ATOM   1534 C  CB  . ARG A 1 219 ? 13.84897  12.49303  -21.76073 1.000 23.46469  ?  219 ARG A CB  1 
ATOM   1535 C  CG  . ARG A 1 219 ? 13.93662  13.74244  -20.89367 1.000 33.53638  ?  219 ARG A CG  1 
ATOM   1536 C  CD  . ARG A 1 219 ? 15.33149  13.94714  -20.32390 1.000 37.33022  ?  219 ARG A CD  1 
ATOM   1537 N  NE  . ARG A 1 219 ? 15.35760  15.00551  -19.32014 1.000 53.88144  ?  219 ARG A NE  1 
ATOM   1538 C  CZ  . ARG A 1 219 ? 16.45884  15.46880  -18.74408 1.000 41.88986  ?  219 ARG A CZ  1 
ATOM   1539 N  NH1 . ARG A 1 219 ? 17.65536  15.00357  -19.06484 1.000 33.77753  ?  219 ARG A NH1 1 
ATOM   1540 N  NH2 . ARG A 1 219 ? 16.35700  16.42379  -17.82342 1.000 27.31132  ?  219 ARG A NH2 1 
ATOM   1541 N  N   . GLY A 1 220 ? 11.08002  11.82094  -20.45666 1.000 24.88788  ?  220 GLY A N   1 
ATOM   1542 C  CA  . GLY A 1 220 ? 10.04570  12.31261  -19.55923 1.000 25.85103  ?  220 GLY A CA  1 
ATOM   1543 C  C   . GLY A 1 220 ? 9.72019   11.34575  -18.43691 1.000 27.82969  ?  220 GLY A C   1 
ATOM   1544 O  O   . GLY A 1 220 ? 9.56978   11.74889  -17.28092 1.000 23.59557  ?  220 GLY A O   1 
ATOM   1545 N  N   . ILE A 1 221 ? 9.61707   10.05923  -18.75755 1.000 31.02766  ?  221 ILE A N   1 
ATOM   1546 C  CA  . ILE A 1 221 ? 9.22237   9.07165   -17.76151 1.000 24.69983  ?  221 ILE A CA  1 
ATOM   1547 C  C   . ILE A 1 221 ? 10.41605  8.53080   -16.97411 1.000 23.75420  ?  221 ILE A C   1 
ATOM   1548 O  O   . ILE A 1 221 ? 10.28662  8.24769   -15.77816 1.000 22.78622  ?  221 ILE A O   1 
ATOM   1549 C  CB  . ILE A 1 221 ? 8.43663   7.93460   -18.44042 1.000 23.04453  ?  221 ILE A CB  1 
ATOM   1550 C  CG1 . ILE A 1 221 ? 8.01380   6.87494   -17.42124 1.000 16.45577  ?  221 ILE A CG1 1 
ATOM   1551 C  CG2 . ILE A 1 221 ? 9.25104   7.31292   -19.56839 1.000 21.08831  ?  221 ILE A CG2 1 
ATOM   1552 C  CD1 . ILE A 1 221 ? 7.12539   5.80192   -18.00041 1.000 16.99772  ?  221 ILE A CD1 1 
ATOM   1553 N  N   . ILE A 1 222 ? 11.58555  8.39639   -17.60545 1.000 21.23715  ?  222 ILE A N   1 
ATOM   1554 C  CA  . ILE A 1 222 ? 12.70732  7.75281   -16.93032 1.000 18.53846  ?  222 ILE A CA  1 
ATOM   1555 C  C   . ILE A 1 222 ? 13.38676  8.66815   -15.91825 1.000 21.69134  ?  222 ILE A C   1 
ATOM   1556 O  O   . ILE A 1 222 ? 14.15062  8.18201   -15.07543 1.000 23.53391  ?  222 ILE A O   1 
ATOM   1557 C  CB  . ILE A 1 222 ? 13.72834  7.23402   -17.95806 1.000 24.20872  ?  222 ILE A CB  1 
ATOM   1558 C  CG1 . ILE A 1 222 ? 14.38427  5.94698   -17.45184 1.000 22.79859  ?  222 ILE A CG1 1 
ATOM   1559 C  CG2 . ILE A 1 222 ? 14.78734  8.29009   -18.25760 1.000 22.81901  ?  222 ILE A CG2 1 
ATOM   1560 C  CD1 . ILE A 1 222 ? 15.20359  5.22805   -18.49834 1.000 22.34671  ?  222 ILE A CD1 1 
ATOM   1561 N  N   . TYR A 1 223 ? 13.13160  9.97398   -15.96402 1.000 25.59395  ?  223 TYR A N   1 
ATOM   1562 C  CA  . TYR A 1 223 ? 13.72018  10.89604  -15.00102 1.000 26.38415  ?  223 TYR A CA  1 
ATOM   1563 C  C   . TYR A 1 223 ? 12.81932  11.16611  -13.80278 1.000 23.85917  ?  223 TYR A C   1 
ATOM   1564 O  O   . TYR A 1 223 ? 13.20645  11.93743  -12.91887 1.000 22.97983  ?  223 TYR A O   1 
ATOM   1565 C  CB  . TYR A 1 223 ? 14.09462  12.21524  -15.68403 1.000 23.31702  ?  223 TYR A CB  1 
ATOM   1566 C  CG  . TYR A 1 223 ? 15.46447  12.18007  -16.32311 1.000 26.81924  ?  223 TYR A CG  1 
ATOM   1567 C  CD1 . TYR A 1 223 ? 15.63881  11.68383  -17.60763 1.000 35.92131  ?  223 TYR A CD1 1 
ATOM   1568 C  CD2 . TYR A 1 223 ? 16.58587  12.62904  -15.63591 1.000 25.56229  ?  223 TYR A CD2 1 
ATOM   1569 C  CE1 . TYR A 1 223 ? 16.88919  11.64237  -18.19519 1.000 41.36313  ?  223 TYR A CE1 1 
ATOM   1570 C  CE2 . TYR A 1 223 ? 17.84200  12.59236  -16.21573 1.000 30.23266  ?  223 TYR A CE2 1 
ATOM   1571 C  CZ  . TYR A 1 223 ? 17.98653  12.09787  -17.49626 1.000 38.36999  ?  223 TYR A CZ  1 
ATOM   1572 O  OH  . TYR A 1 223 ? 19.22956  12.05456  -18.08374 1.000 38.25807  ?  223 TYR A OH  1 
ATOM   1573 N  N   . HIS A 1 224 ? 11.63261  10.56498  -13.75308 1.000 21.21719  ?  224 HIS A N   1 
ATOM   1574 C  CA  . HIS A 1 224 ? 10.85398  10.56689  -12.52268 1.000 18.95279  ?  224 HIS A CA  1 
ATOM   1575 C  C   . HIS A 1 224 ? 11.61155  9.78414   -11.45769 1.000 23.49112  ?  224 HIS A C   1 
ATOM   1576 O  O   . HIS A 1 224 ? 12.13950  8.70475   -11.73195 1.000 28.23036  ?  224 HIS A O   1 
ATOM   1577 C  CB  . HIS A 1 224 ? 9.47596   9.95294   -12.76979 1.000 14.39425  ?  224 HIS A CB  1 
ATOM   1578 C  CG  . HIS A 1 224 ? 8.51774   10.13780  -11.63535 1.000 18.25540  ?  224 HIS A CG  1 
ATOM   1579 N  ND1 . HIS A 1 224 ? 8.62202   11.17474  -10.73382 1.000 23.30549  ?  224 HIS A ND1 1 
ATOM   1580 C  CD2 . HIS A 1 224 ? 7.43663   9.41680   -11.25528 1.000 24.52985  ?  224 HIS A CD2 1 
ATOM   1581 C  CE1 . HIS A 1 224 ? 7.64565   11.08606  -9.84831  1.000 24.86499  ?  224 HIS A CE1 1 
ATOM   1582 N  NE2 . HIS A 1 224 ? 6.91215   10.02781  -10.14216 1.000 25.92470  ?  224 HIS A NE2 1 
ATOM   1583 N  N   . THR A 1 225 ? 11.67540  10.33302  -10.24366 1.000 19.87982  ?  225 THR A N   1 
ATOM   1584 C  CA  . THR A 1 225 ? 12.57065  9.77521   -9.22917  1.000 18.46243  ?  225 THR A CA  1 
ATOM   1585 C  C   . THR A 1 225 ? 12.25853  8.32597   -8.86484  1.000 23.84873  ?  225 THR A C   1 
ATOM   1586 O  O   . THR A 1 225 ? 13.18996  7.50068   -8.87737  1.000 29.95946  ?  225 THR A O   1 
ATOM   1587 C  CB  . THR A 1 225 ? 12.56890  10.67666  -7.98931  1.000 19.67947  ?  225 THR A CB  1 
ATOM   1588 O  OG1 . THR A 1 225 ? 13.12753  11.95281  -8.32457  1.000 25.09977  ?  225 THR A OG1 1 
ATOM   1589 C  CG2 . THR A 1 225 ? 13.38623  10.04809  -6.87101  1.000 23.09018  ?  225 THR A CG2 1 
ATOM   1590 N  N   . PRO A 1 226 ? 11.01771  7.93874   -8.53216  1.000 22.84266  ?  226 PRO A N   1 
ATOM   1591 C  CA  . PRO A 1 226 ? 10.78254  6.51715   -8.21843  1.000 23.79252  ?  226 PRO A CA  1 
ATOM   1592 C  C   . PRO A 1 226 ? 11.05117  5.59734   -9.39557  1.000 26.86655  ?  226 PRO A C   1 
ATOM   1593 O  O   . PRO A 1 226 ? 11.66484  4.53206   -9.22942  1.000 27.90949  ?  226 PRO A O   1 
ATOM   1594 C  CB  . PRO A 1 226 ? 9.30376   6.48909   -7.80047  1.000 31.79968  ?  226 PRO A CB  1 
ATOM   1595 C  CG  . PRO A 1 226 ? 8.96988   7.89808   -7.44902  1.000 25.23737  ?  226 PRO A CG  1 
ATOM   1596 C  CD  . PRO A 1 226 ? 9.78376   8.73066   -8.38086  1.000 24.57173  ?  226 PRO A CD  1 
ATOM   1597 N  N   . ILE A 1 227 ? 10.61178  5.99360   -10.59187 1.000 26.81705  ?  227 ILE A N   1 
ATOM   1598 C  CA  . ILE A 1 227 ? 10.83039  5.17220   -11.77635 1.000 29.02198  ?  227 ILE A CA  1 
ATOM   1599 C  C   . ILE A 1 227 ? 12.31708  5.06550   -12.08379 1.000 24.25799  ?  227 ILE A C   1 
ATOM   1600 O  O   . ILE A 1 227 ? 12.80494  3.99981   -12.46725 1.000 24.54155  ?  227 ILE A O   1 
ATOM   1601 C  CB  . ILE A 1 227 ? 10.03810  5.73242   -12.97152 1.000 27.91906  ?  227 ILE A CB  1 
ATOM   1602 C  CG1 . ILE A 1 227 ? 8.54104   5.74559   -12.65431 1.000 27.27441  ?  227 ILE A CG1 1 
ATOM   1603 C  CG2 . ILE A 1 227 ? 10.30845  4.91342   -14.22466 1.000 20.19071  ?  227 ILE A CG2 1 
ATOM   1604 C  CD1 . ILE A 1 227 ? 7.67042   6.14956   -13.82191 1.000 21.40333  ?  227 ILE A CD1 1 
ATOM   1605 N  N   . ARG A 1 228 ? 13.06095  6.16199   -11.91825 1.000 20.57972  ?  228 ARG A N   1 
ATOM   1606 C  CA  . ARG A 1 228 ? 14.50254  6.12348   -12.14928 1.000 25.01455  ?  228 ARG A CA  1 
ATOM   1607 C  C   . ARG A 1 228 ? 15.20333  5.20886   -11.15184 1.000 28.65662  ?  228 ARG A C   1 
ATOM   1608 O  O   . ARG A 1 228 ? 16.10005  4.44102   -11.52554 1.000 25.72462  ?  228 ARG A O   1 
ATOM   1609 C  CB  . ARG A 1 228 ? 15.08728  7.53363   -12.07700 1.000 21.07683  ?  228 ARG A CB  1 
ATOM   1610 C  CG  . ARG A 1 228 ? 16.60713  7.56596   -12.05996 1.000 25.85660  ?  228 ARG A CG  1 
ATOM   1611 C  CD  . ARG A 1 228 ? 17.18946  6.96624   -13.32849 1.000 17.74652  ?  228 ARG A CD  1 
ATOM   1612 N  NE  . ARG A 1 228 ? 16.95254  7.81947   -14.48492 1.000 17.68897  ?  228 ARG A NE  1 
ATOM   1613 C  CZ  . ARG A 1 228 ? 17.85123  8.64456   -15.00251 1.000 19.87649  ?  228 ARG A CZ  1 
ATOM   1614 N  NH1 . ARG A 1 228 ? 19.07483  8.73123   -14.50980 1.000 17.66051  ?  228 ARG A NH1 1 
ATOM   1615 N  NH2 . ARG A 1 228 ? 17.51425  9.39983   -16.04225 1.000 24.31338  ?  228 ARG A NH2 1 
ATOM   1616 N  N   . ARG A 1 229 ? 14.81998  5.28497   -9.87492  1.000 31.00160  ?  229 ARG A N   1 
ATOM   1617 C  CA  . ARG A 1 229 ? 15.41631  4.40114   -8.87832  1.000 31.41417  ?  229 ARG A CA  1 
ATOM   1618 C  C   . ARG A 1 229 ? 15.14220  2.94076   -9.21389  1.000 35.41261  ?  229 ARG A C   1 
ATOM   1619 O  O   . ARG A 1 229 ? 16.04912  2.09756   -9.17752  1.000 31.15898  ?  229 ARG A O   1 
ATOM   1620 C  CB  . ARG A 1 229 ? 14.88207  4.73539   -7.48610  1.000 30.75024  ?  229 ARG A CB  1 
ATOM   1621 C  CG  . ARG A 1 229 ? 15.34166  3.75295   -6.42486  1.000 29.45566  ?  229 ARG A CG  1 
ATOM   1622 C  CD  . ARG A 1 229 ? 14.49892  3.82312   -5.16826  1.000 38.59854  ?  229 ARG A CD  1 
ATOM   1623 N  NE  . ARG A 1 229 ? 14.95506  2.87005   -4.16271  1.000 51.71613  ?  229 ARG A NE  1 
ATOM   1624 C  CZ  . ARG A 1 229 ? 14.55167  1.60907   -4.08271  1.000 53.86247  ?  229 ARG A CZ  1 
ATOM   1625 N  NH1 . ARG A 1 229 ? 13.68040  1.10558   -4.94219  1.000 37.18952  ?  229 ARG A NH1 1 
ATOM   1626 N  NH2 . ARG A 1 229 ? 15.03518  0.83342   -3.11598  1.000 43.20738  ?  229 ARG A NH2 1 
ATOM   1627 N  N   . ASP A 1 230 ? 13.89093  2.62593   -9.55893  1.000 36.64989  ?  230 ASP A N   1 
ATOM   1628 C  CA  . ASP A 1 230 ? 13.54837  1.24844   -9.89338  1.000 36.88046  ?  230 ASP A CA  1 
ATOM   1629 C  C   . ASP A 1 230 ? 14.23167  0.79698   -11.17997 1.000 34.19278  ?  230 ASP A C   1 
ATOM   1630 O  O   . ASP A 1 230 ? 14.60200  -0.37440  -11.30508 1.000 27.53135  ?  230 ASP A O   1 
ATOM   1631 C  CB  . ASP A 1 230 ? 12.03053  1.10151   -9.99548  1.000 26.05040  ?  230 ASP A CB  1 
ATOM   1632 C  CG  . ASP A 1 230 ? 11.32820  1.37839   -8.67643  1.000 36.20411  ?  230 ASP A CG  1 
ATOM   1633 O  OD1 . ASP A 1 230 ? 12.02199  1.56388   -7.65404  1.000 35.79086  ?  230 ASP A OD1 1 
ATOM   1634 O  OD2 . ASP A 1 230 ? 10.08067  1.41206   -8.65938  1.000 47.64344  -1 230 ASP A OD2 1 
ATOM   1635 N  N   . TYR A 1 231 ? 14.43301  1.71243   -12.13048 1.000 28.67995  ?  231 TYR A N   1 
ATOM   1636 C  CA  . TYR A 1 231 ? 15.11852  1.37355   -13.37296 1.000 22.77195  ?  231 TYR A CA  1 
ATOM   1637 C  C   . TYR A 1 231 ? 16.59357  1.07996   -13.13091 1.000 22.04554  ?  231 TYR A C   1 
ATOM   1638 O  O   . TYR A 1 231 ? 17.15295  0.15837   -13.73170 1.000 21.76040  ?  231 TYR A O   1 
ATOM   1639 C  CB  . TYR A 1 231 ? 14.94900  2.51171   -14.37974 1.000 22.29799  ?  231 TYR A CB  1 
ATOM   1640 C  CG  . TYR A 1 231 ? 15.47636  2.21596   -15.76599 1.000 19.52728  ?  231 TYR A CG  1 
ATOM   1641 C  CD1 . TYR A 1 231 ? 14.68456  1.57265   -16.70884 1.000 16.99500  ?  231 TYR A CD1 1 
ATOM   1642 C  CD2 . TYR A 1 231 ? 16.75914  2.59572   -16.13795 1.000 17.06630  ?  231 TYR A CD2 1 
ATOM   1643 C  CE1 . TYR A 1 231 ? 15.15929  1.30756   -17.97949 1.000 15.91831  ?  231 TYR A CE1 1 
ATOM   1644 C  CE2 . TYR A 1 231 ? 17.24246  2.33324   -17.40527 1.000 15.52375  ?  231 TYR A CE2 1 
ATOM   1645 C  CZ  . TYR A 1 231 ? 16.43947  1.68960   -18.32179 1.000 16.86878  ?  231 TYR A CZ  1 
ATOM   1646 O  OH  . TYR A 1 231 ? 16.91838  1.42727   -19.58476 1.000 16.01425  ?  231 TYR A OH  1 
ATOM   1647 N  N   . TYR A 1 232 ? 17.24520  1.85975   -12.26496 1.000 25.83133  ?  232 TYR A N   1 
ATOM   1648 C  CA  . TYR A 1 232 ? 18.63085  1.56353   -11.90560 1.000 27.96934  ?  232 TYR A CA  1 
ATOM   1649 C  C   . TYR A 1 232 ? 18.73012  0.23542   -11.16129 1.000 30.59343  ?  232 TYR A C   1 
ATOM   1650 O  O   . TYR A 1 232 ? 19.65965  -0.55684  -11.38896 1.000 26.08448  ?  232 TYR A O   1 
ATOM   1651 C  CB  . TYR A 1 232 ? 19.20468  2.70420   -11.06533 1.000 22.28221  ?  232 TYR A CB  1 
ATOM   1652 C  CG  . TYR A 1 232 ? 20.64187  2.50236   -10.64612 1.000 20.94413  ?  232 TYR A CG  1 
ATOM   1653 C  CD1 . TYR A 1 232 ? 21.68328  2.74640   -11.53085 1.000 20.05317  ?  232 TYR A CD1 1 
ATOM   1654 C  CD2 . TYR A 1 232 ? 20.95809  2.07684   -9.36210  1.000 21.08233  ?  232 TYR A CD2 1 
ATOM   1655 C  CE1 . TYR A 1 232 ? 22.99904  2.56564   -11.15152 1.000 23.35073  ?  232 TYR A CE1 1 
ATOM   1656 C  CE2 . TYR A 1 232 ? 22.27078  1.89361   -8.97266  1.000 20.04866  ?  232 TYR A CE2 1 
ATOM   1657 C  CZ  . TYR A 1 232 ? 23.28715  2.13959   -9.87156  1.000 21.45087  ?  232 TYR A CZ  1 
ATOM   1658 O  OH  . TYR A 1 232 ? 24.59734  1.95969   -9.49278  1.000 19.43831  ?  232 TYR A OH  1 
ATOM   1659 N  N   . ARG A 1 233 ? 17.77773  -0.02013  -10.26009 1.000 31.58633  ?  233 ARG A N   1 
ATOM   1660 C  CA  . ARG A 1 233 ? 17.69088  -1.32550  -9.61538  1.000 30.97401  ?  233 ARG A CA  1 
ATOM   1661 C  C   . ARG A 1 233 ? 17.57922  -2.43952  -10.64855 1.000 28.60311  ?  233 ARG A C   1 
ATOM   1662 O  O   . ARG A 1 233 ? 18.22996  -3.48513  -10.52483 1.000 26.81377  ?  233 ARG A O   1 
ATOM   1663 C  CB  . ARG A 1 233 ? 16.49213  -1.34722  -8.66876  1.000 31.27936  ?  233 ARG A CB  1 
ATOM   1664 C  CG  . ARG A 1 233 ? 16.04882  -2.72911  -8.24869  1.000 27.45391  ?  233 ARG A CG  1 
ATOM   1665 C  CD  . ARG A 1 233 ? 16.98382  -3.32029  -7.21696  1.000 25.11832  ?  233 ARG A CD  1 
ATOM   1666 N  NE  . ARG A 1 233 ? 16.46171  -4.57745  -6.69904  1.000 37.34866  ?  233 ARG A NE  1 
ATOM   1667 C  CZ  . ARG A 1 233 ? 16.89098  -5.16966  -5.59425  1.000 40.81767  ?  233 ARG A CZ  1 
ATOM   1668 N  NH1 . ARG A 1 233 ? 17.85626  -4.64295  -4.85831  1.000 36.64352  ?  233 ARG A NH1 1 
ATOM   1669 N  NH2 . ARG A 1 233 ? 16.33190  -6.31502  -5.21488  1.000 46.25650  ?  233 ARG A NH2 1 
ATOM   1670 N  N   . GLN A 1 234 ? 16.75740  -2.22685  -11.67773 1.000 27.50909  ?  234 GLN A N   1 
ATOM   1671 C  CA  . GLN A 1 234 ? 16.61074  -3.21321  -12.74153 1.000 24.79481  ?  234 GLN A CA  1 
ATOM   1672 C  C   . GLN A 1 234 ? 17.90160  -3.38309  -13.52857 1.000 22.77376  ?  234 GLN A C   1 
ATOM   1673 O  O   . GLN A 1 234 ? 18.22183  -4.49100  -13.96428 1.000 20.44227  ?  234 GLN A O   1 
ATOM   1674 C  CB  . GLN A 1 234 ? 15.46673  -2.81552  -13.66865 1.000 19.32099  ?  234 GLN A CB  1 
ATOM   1675 C  CG  . GLN A 1 234 ? 14.13443  -3.35734  -13.22172 1.000 23.83376  ?  234 GLN A CG  1 
ATOM   1676 C  CD  . GLN A 1 234 ? 14.11080  -4.87108  -13.20897 1.000 26.07864  ?  234 GLN A CD  1 
ATOM   1677 O  OE1 . GLN A 1 234 ? 14.55131  -5.51846  -14.15941 1.000 26.57133  ?  234 GLN A OE1 1 
ATOM   1678 N  NE2 . GLN A 1 234 ? 13.60513  -5.44515  -12.12493 1.000 33.00049  ?  234 GLN A NE2 1 
ATOM   1679 N  N   . ILE A 1 235 ? 18.63719  -2.29400  -13.74931 1.000 24.70565  ?  235 ILE A N   1 
ATOM   1680 C  CA  . ILE A 1 235 ? 19.94129  -2.40177  -14.39911 1.000 21.01598  ?  235 ILE A CA  1 
ATOM   1681 C  C   . ILE A 1 235 ? 20.83591  -3.34350  -13.60761 1.000 25.39694  ?  235 ILE A C   1 
ATOM   1682 O  O   . ILE A 1 235 ? 21.44264  -4.27329  -14.15928 1.000 27.84844  ?  235 ILE A O   1 
ATOM   1683 C  CB  . ILE A 1 235 ? 20.58987  -1.01375  -14.54591 1.000 17.03177  ?  235 ILE A CB  1 
ATOM   1684 C  CG1 . ILE A 1 235 ? 19.75965  -0.11581  -15.45935 1.000 21.13151  ?  235 ILE A CG1 1 
ATOM   1685 C  CG2 . ILE A 1 235 ? 22.00793  -1.14327  -15.07757 1.000 18.24984  ?  235 ILE A CG2 1 
ATOM   1686 C  CD1 . ILE A 1 235 ? 20.24812  1.31181   -15.49131 1.000 23.71797  ?  235 ILE A CD1 1 
ATOM   1687 N  N   . LEU A 1 236 ? 20.91027  -3.12316  -12.29257 1.000 25.97976  ?  236 LEU A N   1 
ATOM   1688 C  CA  . LEU A 1 236 ? 21.73024  -3.98271  -11.44209 1.000 23.17186  ?  236 LEU A CA  1 
ATOM   1689 C  C   . LEU A 1 236 ? 21.26771  -5.43417  -11.51816 1.000 26.85593  ?  236 LEU A C   1 
ATOM   1690 O  O   . LEU A 1 236 ? 22.08246  -6.35114  -11.68424 1.000 24.96258  ?  236 LEU A O   1 
ATOM   1691 C  CB  . LEU A 1 236 ? 21.69533  -3.48372  -9.99693  1.000 20.23154  ?  236 LEU A CB  1 
ATOM   1692 C  CG  . LEU A 1 236 ? 22.43864  -2.18380  -9.68932  1.000 20.19346  ?  236 LEU A CG  1 
ATOM   1693 C  CD1 . LEU A 1 236 ? 22.30497  -1.83059  -8.21678  1.000 22.84918  ?  236 LEU A CD1 1 
ATOM   1694 C  CD2 . LEU A 1 236 ? 23.90150  -2.29949  -10.08395 1.000 17.69810  ?  236 LEU A CD2 1 
ATOM   1695 N  N   . GLU A 1 237 ? 19.95470  -5.65813  -11.41431 1.000 29.88484  ?  237 GLU A N   1 
ATOM   1696 C  CA  . GLU A 1 237 ? 19.42771  -7.02126  -11.40330 1.000 27.26126  ?  237 GLU A CA  1 
ATOM   1697 C  C   . GLU A 1 237 ? 19.69243  -7.73233  -12.72493 1.000 27.54897  ?  237 GLU A C   1 
ATOM   1698 O  O   . GLU A 1 237 ? 20.11756  -8.89286  -12.74419 1.000 32.55251  ?  237 GLU A O   1 
ATOM   1699 C  CB  . GLU A 1 237 ? 17.92867  -7.00631  -11.10206 1.000 23.98671  ?  237 GLU A CB  1 
ATOM   1700 C  CG  . GLU A 1 237 ? 17.57391  -6.62145  -9.68046  1.000 26.50969  ?  237 GLU A CG  1 
ATOM   1701 C  CD  . GLU A 1 237 ? 16.11237  -6.86129  -9.36771  1.000 32.46890  ?  237 GLU A CD  1 
ATOM   1702 O  OE1 . GLU A 1 237 ? 15.32927  -7.07010  -10.31797 1.000 30.51157  ?  237 GLU A OE1 1 
ATOM   1703 O  OE2 . GLU A 1 237 ? 15.74791  -6.84850  -8.17318  1.000 43.33607  -1 237 GLU A OE2 1 
ATOM   1704 N  N   . GLU A 1 238 ? 19.43746  -7.05086  -13.84394 1.000 25.57549  ?  238 GLU A N   1 
ATOM   1705 C  CA  . GLU A 1 238 ? 19.60626  -7.66878  -15.15310 1.000 22.16381  ?  238 GLU A CA  1 
ATOM   1706 C  C   . GLU A 1 238 ? 21.07136  -7.95637  -15.44423 1.000 26.75048  ?  238 GLU A C   1 
ATOM   1707 O  O   . GLU A 1 238 ? 21.39792  -8.99504  -16.03088 1.000 30.50333  ?  238 GLU A O   1 
ATOM   1708 C  CB  . GLU A 1 238 ? 19.00343  -6.77615  -16.23800 1.000 18.33146  ?  238 GLU A CB  1 
ATOM   1709 C  CG  . GLU A 1 238 ? 17.49048  -6.65440  -16.16386 1.000 22.05935  ?  238 GLU A CG  1 
ATOM   1710 C  CD  . GLU A 1 238 ? 16.92323  -5.74533  -17.23606 1.000 26.58279  ?  238 GLU A CD  1 
ATOM   1711 O  OE1 . GLU A 1 238 ? 17.67446  -5.37465  -18.16381 1.000 24.52500  ?  238 GLU A OE1 1 
ATOM   1712 O  OE2 . GLU A 1 238 ? 15.72520  -5.40036  -17.14969 1.000 26.26317  -1 238 GLU A OE2 1 
ATOM   1713 N  N   . PHE A 1 239 ? 21.97372  -7.05306  -15.04966 1.000 27.86151  ?  239 PHE A N   1 
ATOM   1714 C  CA  . PHE A 1 239 ? 23.38622  -7.32619  -15.28165 1.000 21.23467  ?  239 PHE A CA  1 
ATOM   1715 C  C   . PHE A 1 239 ? 23.90357  -8.43126  -14.36983 1.000 23.69577  ?  239 PHE A C   1 
ATOM   1716 O  O   . PHE A 1 239 ? 24.75911  -9.21885  -14.78794 1.000 25.37797  ?  239 PHE A O   1 
ATOM   1717 C  CB  . PHE A 1 239 ? 24.20488  -6.04613  -15.12957 1.000 17.78610  ?  239 PHE A CB  1 
ATOM   1718 C  CG  . PHE A 1 239 ? 24.31445  -5.25996  -16.40234 1.000 14.95302  ?  239 PHE A CG  1 
ATOM   1719 C  CD1 . PHE A 1 239 ? 23.28637  -4.42697  -16.80740 1.000 15.77985  ?  239 PHE A CD1 1 
ATOM   1720 C  CD2 . PHE A 1 239 ? 25.43393  -5.37569  -17.20824 1.000 18.36182  ?  239 PHE A CD2 1 
ATOM   1721 C  CE1 . PHE A 1 239 ? 23.37804  -3.71302  -17.98462 1.000 16.48373  ?  239 PHE A CE1 1 
ATOM   1722 C  CE2 . PHE A 1 239 ? 25.53239  -4.66402  -18.38667 1.000 17.26249  ?  239 PHE A CE2 1 
ATOM   1723 C  CZ  . PHE A 1 239 ? 24.50195  -3.83226  -18.77579 1.000 19.92977  ?  239 PHE A CZ  1 
ATOM   1724 N  N   . ARG A 1 240 ? 23.39495  -8.52487  -13.13721 1.000 24.68243  ?  240 ARG A N   1 
ATOM   1725 C  CA  . ARG A 1 240 ? 23.76254  -9.65386  -12.28793 1.000 29.51590  ?  240 ARG A CA  1 
ATOM   1726 C  C   . ARG A 1 240 ? 23.25603  -10.96887 -12.86753 1.000 28.19193  ?  240 ARG A C   1 
ATOM   1727 O  O   . ARG A 1 240 ? 23.97158  -11.97761 -12.85634 1.000 28.72020  ?  240 ARG A O   1 
ATOM   1728 C  CB  . ARG A 1 240 ? 23.21836  -9.46095  -10.87397 1.000 30.33144  ?  240 ARG A CB  1 
ATOM   1729 C  CG  . ARG A 1 240 ? 23.47300  -10.65996 -9.97418  1.000 27.38766  ?  240 ARG A CG  1 
ATOM   1730 C  CD  . ARG A 1 240 ? 22.56609  -10.66641 -8.75993  1.000 26.75928  ?  240 ARG A CD  1 
ATOM   1731 N  NE  . ARG A 1 240 ? 22.77669  -11.85889 -7.94872  1.000 24.34360  ?  240 ARG A NE  1 
ATOM   1732 C  CZ  . ARG A 1 240 ? 22.14339  -13.00938 -8.13051  1.000 28.09030  ?  240 ARG A CZ  1 
ATOM   1733 N  NH1 . ARG A 1 240 ? 21.24227  -13.15855 -9.08750  1.000 34.51067  ?  240 ARG A NH1 1 
ATOM   1734 N  NH2 . ARG A 1 240 ? 22.41980  -14.03541 -7.33077  1.000 32.42320  ?  240 ARG A NH2 1 
ATOM   1735 N  N   . SER A 1 241 ? 22.01881  -10.97741 -13.37307 1.000 23.31222  ?  241 SER A N   1 
ATOM   1736 C  CA  . SER A 1 241 ? 21.43726  -12.20561 -13.90488 1.000 21.02336  ?  241 SER A CA  1 
ATOM   1737 C  C   . SER A 1 241 ? 22.20744  -12.71558 -15.11394 1.000 22.13740  ?  241 SER A C   1 
ATOM   1738 O  O   . SER A 1 241 ? 22.27798  -13.92935 -15.33780 1.000 25.72714  ?  241 SER A O   1 
ATOM   1739 C  CB  . SER A 1 241 ? 19.96966  -11.97788 -14.26641 1.000 21.30521  ?  241 SER A CB  1 
ATOM   1740 O  OG  . SER A 1 241 ? 19.20832  -11.65090 -13.11694 1.000 25.97993  ?  241 SER A OG  1 
ATOM   1741 N  N   . ASP A 1 242 ? 22.79170  -11.81371 -15.89992 1.000 23.45643  ?  242 ASP A N   1 
ATOM   1742 C  CA  . ASP A 1 242 ? 23.63285  -12.20021 -17.02290 1.000 25.29256  ?  242 ASP A CA  1 
ATOM   1743 C  C   . ASP A 1 242 ? 25.05227  -12.55083 -16.59271 1.000 24.87224  ?  242 ASP A C   1 
ATOM   1744 O  O   . ASP A 1 242 ? 25.94664  -12.61634 -17.44303 1.000 24.62452  ?  242 ASP A O   1 
ATOM   1745 C  CB  . ASP A 1 242 ? 23.65865  -11.08390 -18.07101 1.000 22.53790  ?  242 ASP A CB  1 
ATOM   1746 C  CG  . ASP A 1 242 ? 23.86554  -11.60998 -19.47858 1.000 19.14380  ?  242 ASP A CG  1 
ATOM   1747 O  OD1 . ASP A 1 242 ? 23.75490  -12.83803 -19.67714 1.000 25.52832  ?  242 ASP A OD1 1 
ATOM   1748 O  OD2 . ASP A 1 242 ? 24.13892  -10.79660 -20.38567 1.000 17.47357  -1 242 ASP A OD2 1 
ATOM   1749 N  N   . ASN A 1 243 ? 25.26116  -12.76915 -15.29219 1.000 26.14631  ?  243 ASN A N   1 
ATOM   1750 C  CA  . ASN A 1 243 ? 26.56032  -13.13395 -14.72526 1.000 32.09541  ?  243 ASN A CA  1 
ATOM   1751 C  C   . ASN A 1 243 ? 27.60814  -12.04357 -14.93726 1.000 32.52936  ?  243 ASN A C   1 
ATOM   1752 O  O   . ASN A 1 243 ? 28.79706  -12.32832 -15.09661 1.000 24.21460  ?  243 ASN A O   1 
ATOM   1753 C  CB  . ASN A 1 243 ? 27.05103  -14.47522 -15.27621 1.000 24.64194  ?  243 ASN A CB  1 
ATOM   1754 C  CG  . ASN A 1 243 ? 26.17929  -15.63292 -14.83661 1.000 31.15738  ?  243 ASN A CG  1 
ATOM   1755 O  OD1 . ASN A 1 243 ? 26.22090  -16.05000 -13.67912 1.000 43.82366  ?  243 ASN A OD1 1 
ATOM   1756 N  ND2 . ASN A 1 243 ? 25.38109  -16.15743 -15.75814 1.000 33.86941  ?  243 ASN A ND2 1 
ATOM   1757 N  N   . VAL A 1 244 ? 27.17551  -10.78716 -14.93834 1.000 24.54049  ?  244 VAL A N   1 
ATOM   1758 C  CA  . VAL A 1 244 ? 28.06941  -9.63761  -14.87710 1.000 25.12981  ?  244 VAL A CA  1 
ATOM   1759 C  C   . VAL A 1 244 ? 27.95577  -9.06954  -13.46952 1.000 24.76065  ?  244 VAL A C   1 
ATOM   1760 O  O   . VAL A 1 244 ? 26.85988  -8.70071  -13.02899 1.000 26.91093  ?  244 VAL A O   1 
ATOM   1761 C  CB  . VAL A 1 244 ? 27.72261  -8.58456  -15.94111 1.000 27.14832  ?  244 VAL A CB  1 
ATOM   1762 C  CG1 . VAL A 1 244 ? 28.73554  -7.44843  -15.92381 1.000 21.40782  ?  244 VAL A CG1 1 
ATOM   1763 C  CG2 . VAL A 1 244 ? 27.65366  -9.22562  -17.31913 1.000 22.68692  ?  244 VAL A CG2 1 
ATOM   1764 N  N   . GLN A 1 245 ? 29.07960  -9.00880  -12.75780 1.000 22.81332  ?  245 GLN A N   1 
ATOM   1765 C  CA  . GLN A 1 245 ? 29.05364  -8.71923  -11.33062 1.000 25.15601  ?  245 GLN A CA  1 
ATOM   1766 C  C   . GLN A 1 245 ? 29.43377  -7.28376  -10.99166 1.000 25.49431  ?  245 GLN A C   1 
ATOM   1767 O  O   . GLN A 1 245 ? 29.16825  -6.84056  -9.86971  1.000 24.59848  ?  245 GLN A O   1 
ATOM   1768 C  CB  . GLN A 1 245 ? 29.98327  -9.68820  -10.58770 1.000 31.30350  ?  245 GLN A CB  1 
ATOM   1769 C  CG  . GLN A 1 245 ? 29.62955  -11.15476 -10.79616 1.000 25.58775  ?  245 GLN A CG  1 
ATOM   1770 C  CD  . GLN A 1 245 ? 30.84249  -12.06390 -10.73776 1.000 29.41340  ?  245 GLN A CD  1 
ATOM   1771 O  OE1 . GLN A 1 245 ? 31.27016  -12.60992 -11.75576 1.000 26.98055  ?  245 GLN A OE1 1 
ATOM   1772 N  NE2 . GLN A 1 245 ? 31.40162  -12.23411 -9.54387  1.000 25.32261  ?  245 GLN A NE2 1 
ATOM   1773 N  N   . TYR A 1 246 ? 30.03329  -6.54823  -11.92378 1.000 27.27608  ?  246 TYR A N   1 
ATOM   1774 C  CA  . TYR A 1 246 ? 30.46543  -5.18047  -11.67829 1.000 21.05025  ?  246 TYR A CA  1 
ATOM   1775 C  C   . TYR A 1 246 ? 30.11120  -4.32486  -12.88442 1.000 19.38995  ?  246 TYR A C   1 
ATOM   1776 O  O   . TYR A 1 246 ? 30.18415  -4.79120  -14.02372 1.000 21.12818  ?  246 TYR A O   1 
ATOM   1777 C  CB  . TYR A 1 246 ? 31.97368  -5.12932  -11.39663 1.000 21.75283  ?  246 TYR A CB  1 
ATOM   1778 C  CG  . TYR A 1 246 ? 32.54259  -3.74063  -11.22056 1.000 24.34934  ?  246 TYR A CG  1 
ATOM   1779 C  CD1 . TYR A 1 246 ? 32.32883  -3.02231  -10.05132 1.000 25.34132  ?  246 TYR A CD1 1 
ATOM   1780 C  CD2 . TYR A 1 246 ? 33.31400  -3.15699  -12.21654 1.000 24.37139  ?  246 TYR A CD2 1 
ATOM   1781 C  CE1 . TYR A 1 246 ? 32.85568  -1.75455  -9.88596  1.000 21.47216  ?  246 TYR A CE1 1 
ATOM   1782 C  CE2 . TYR A 1 246 ? 33.84609  -1.89387  -12.05975 1.000 19.58799  ?  246 TYR A CE2 1 
ATOM   1783 C  CZ  . TYR A 1 246 ? 33.61315  -1.19582  -10.89425 1.000 18.14352  ?  246 TYR A CZ  1 
ATOM   1784 O  OH  . TYR A 1 246 ? 34.14200  0.06416   -10.73788 1.000 14.62518  ?  246 TYR A OH  1 
ATOM   1785 N  N   . VAL A 1 247 ? 29.70393  -3.08115  -12.63497 1.000 18.06172  ?  247 VAL A N   1 
ATOM   1786 C  CA  . VAL A 1 247 ? 29.35982  -2.15607  -13.70811 1.000 21.45228  ?  247 VAL A CA  1 
ATOM   1787 C  C   . VAL A 1 247 ? 29.89822  -0.77216  -13.37532 1.000 13.75389  ?  247 VAL A C   1 
ATOM   1788 O  O   . VAL A 1 247 ? 30.05504  -0.40712  -12.20634 1.000 13.17846  ?  247 VAL A O   1 
ATOM   1789 C  CB  . VAL A 1 247 ? 27.83419  -2.08906  -13.96505 1.000 20.14589  ?  247 VAL A CB  1 
ATOM   1790 C  CG1 . VAL A 1 247 ? 27.32738  -3.39081  -14.57148 1.000 17.45177  ?  247 VAL A CG1 1 
ATOM   1791 C  CG2 . VAL A 1 247 ? 27.08813  -1.76880  -12.68322 1.000 15.83138  ?  247 VAL A CG2 1 
ATOM   1792 N  N   . GLU A 1 248 ? 30.18635  -0.00232  -14.42351 1.000 11.95233  ?  248 GLU A N   1 
ATOM   1793 C  CA  . GLU A 1 248 ? 30.55835  1.40678   -14.30649 1.000 11.47951  ?  248 GLU A CA  1 
ATOM   1794 C  C   . GLU A 1 248 ? 29.62288  2.18521   -15.22569 1.000 18.94778  ?  248 GLU A C   1 
ATOM   1795 O  O   . GLU A 1 248 ? 29.78672  2.17379   -16.44978 1.000 16.73263  ?  248 GLU A O   1 
ATOM   1796 C  CB  . GLU A 1 248 ? 32.02424  1.63550   -14.65822 1.000 11.97623  ?  248 GLU A CB  1 
ATOM   1797 C  CG  . GLU A 1 248 ? 32.98491  1.02491   -13.65512 1.000 14.82953  ?  248 GLU A CG  1 
ATOM   1798 C  CD  . GLU A 1 248 ? 34.41391  1.48655   -13.84869 1.000 16.70017  ?  248 GLU A CD  1 
ATOM   1799 O  OE1 . GLU A 1 248 ? 34.63056  2.44772   -14.61417 1.000 16.58731  ?  248 GLU A OE1 1 
ATOM   1800 O  OE2 . GLU A 1 248 ? 35.32108  0.89009   -13.23107 1.000 18.15549  -1 248 GLU A OE2 1 
ATOM   1801 N  N   . VAL A 1 249 ? 28.64870  2.86402   -14.62820 1.000 23.85178  ?  249 VAL A N   1 
ATOM   1802 C  CA  . VAL A 1 249 ? 27.51532  3.43028   -15.34822 1.000 22.58315  ?  249 VAL A CA  1 
ATOM   1803 C  C   . VAL A 1 249 ? 27.70739  4.93308   -15.49057 1.000 23.72365  ?  249 VAL A C   1 
ATOM   1804 O  O   . VAL A 1 249 ? 28.01152  5.62498   -14.51125 1.000 24.67620  ?  249 VAL A O   1 
ATOM   1805 C  CB  . VAL A 1 249 ? 26.19529  3.11378   -14.62603 1.000 15.78282  ?  249 VAL A CB  1 
ATOM   1806 C  CG1 . VAL A 1 249 ? 25.02100  3.44079   -15.51642 1.000 20.96569  ?  249 VAL A CG1 1 
ATOM   1807 C  CG2 . VAL A 1 249 ? 26.16158  1.65388   -14.19847 1.000 16.38540  ?  249 VAL A CG2 1 
ATOM   1808 N  N   . ARG A 1 250 ? 27.52480  5.43869   -16.70777 1.000 23.56734  ?  250 ARG A N   1 
ATOM   1809 C  CA  . ARG A 1 250 ? 27.57202  6.87010   -16.97320 1.000 21.61942  ?  250 ARG A CA  1 
ATOM   1810 C  C   . ARG A 1 250 ? 26.17149  7.45900   -16.85955 1.000 18.74119  ?  250 ARG A C   1 
ATOM   1811 O  O   . ARG A 1 250 ? 25.21981  6.93015   -17.44174 1.000 23.93929  ?  250 ARG A O   1 
ATOM   1812 C  CB  . ARG A 1 250 ? 28.15639  7.14241   -18.35890 1.000 16.29214  ?  250 ARG A CB  1 
ATOM   1813 C  CG  . ARG A 1 250 ? 29.64794  6.87817   -18.45356 1.000 15.19429  ?  250 ARG A CG  1 
ATOM   1814 C  CD  . ARG A 1 250 ? 30.11699  6.86643   -19.89577 1.000 16.08384  ?  250 ARG A CD  1 
ATOM   1815 N  NE  . ARG A 1 250 ? 31.56233  6.70705   -20.00066 1.000 15.74529  ?  250 ARG A NE  1 
ATOM   1816 C  CZ  . ARG A 1 250 ? 32.20376  5.55797   -19.83598 1.000 23.42411  ?  250 ARG A CZ  1 
ATOM   1817 N  NH1 . ARG A 1 250 ? 31.56035  4.44491   -19.52281 1.000 21.60891  ?  250 ARG A NH1 1 
ATOM   1818 N  NH2 . ARG A 1 250 ? 33.52468  5.52498   -19.98621 1.000 25.58406  ?  250 ARG A NH2 1 
ATOM   1819 N  N   . SER A 1 251 ? 26.05111  8.55254   -16.11010 1.000 17.96278  ?  251 SER A N   1 
ATOM   1820 C  CA  . SER A 1 251 ? 24.75707  9.15187   -15.82334 1.000 21.38634  ?  251 SER A CA  1 
ATOM   1821 C  C   . SER A 1 251 ? 24.89895  10.66482  -15.75328 1.000 23.80025  ?  251 SER A C   1 
ATOM   1822 O  O   . SER A 1 251 ? 25.94885  11.18655  -15.36933 1.000 27.50245  ?  251 SER A O   1 
ATOM   1823 C  CB  . SER A 1 251 ? 24.17980  8.61701   -14.50679 1.000 24.15813  ?  251 SER A CB  1 
ATOM   1824 O  OG  . SER A 1 251 ? 23.02248  9.33807   -14.12217 1.000 22.67870  ?  251 SER A OG  1 
ATOM   1825 N  N   . SER A 1 252 ? 23.82754  11.36565  -16.13439 1.000 19.09632  ?  252 SER A N   1 
ATOM   1826 C  CA  . SER A 1 252 ? 23.78461  12.81413  -15.96342 1.000 25.32286  ?  252 SER A CA  1 
ATOM   1827 C  C   . SER A 1 252 ? 23.48150  13.20608  -14.52160 1.000 31.16638  ?  252 SER A C   1 
ATOM   1828 O  O   . SER A 1 252 ? 23.84645  14.30826  -14.09558 1.000 32.79962  ?  252 SER A O   1 
ATOM   1829 C  CB  . SER A 1 252 ? 22.74936  13.42617  -16.90727 1.000 30.71728  ?  252 SER A CB  1 
ATOM   1830 O  OG  . SER A 1 252 ? 21.45836  12.90710  -16.64740 1.000 36.82334  ?  252 SER A OG  1 
ATOM   1831 N  N   . LEU A 1 253 ? 22.77690  12.34065  -13.78630 1.000 27.40856  ?  253 LEU A N   1 
ATOM   1832 C  CA  . LEU A 1 253 ? 22.60910  12.41319  -12.33591 1.000 20.41740  ?  253 LEU A CA  1 
ATOM   1833 C  C   . LEU A 1 253 ? 21.68260  13.53267  -11.87307 1.000 24.97801  ?  253 LEU A C   1 
ATOM   1834 O  O   . LEU A 1 253 ? 21.30378  13.57045  -10.69831 1.000 35.02822  ?  253 LEU A O   1 
ATOM   1835 C  CB  . LEU A 1 253 ? 23.96940  12.57028  -11.64808 1.000 20.04757  ?  253 LEU A CB  1 
ATOM   1836 C  CG  . LEU A 1 253 ? 24.91803  11.37485  -11.68954 1.000 22.49711  ?  253 LEU A CG  1 
ATOM   1837 C  CD1 . LEU A 1 253 ? 26.26539  11.75183  -11.09506 1.000 15.68984  ?  253 LEU A CD1 1 
ATOM   1838 C  CD2 . LEU A 1 253 ? 24.30717  10.19964  -10.94490 1.000 27.97519  ?  253 LEU A CD2 1 
ATOM   1839 N  N   . SER A 1 254 ? 21.27375  14.41929  -12.77471 1.000 26.42661  ?  254 SER A N   1 
ATOM   1840 C  CA  . SER A 1 254 ? 20.48973  15.58421  -12.39740 1.000 22.94848  ?  254 SER A CA  1 
ATOM   1841 C  C   . SER A 1 254 ? 19.18991  15.62205  -13.18732 1.000 28.72457  ?  254 SER A C   1 
ATOM   1842 O  O   . SER A 1 254 ? 19.07386  15.03974  -14.26933 1.000 32.55688  ?  254 SER A O   1 
ATOM   1843 C  CB  . SER A 1 254 ? 21.27316  16.88682  -12.61722 1.000 19.38431  ?  254 SER A CB  1 
ATOM   1844 O  OG  . SER A 1 254 ? 21.50885  17.11987  -13.99480 1.000 26.21939  ?  254 SER A OG  1 
ATOM   1845 N  N   . GLY A 1 255 ? 18.20647  16.31925  -12.62453 1.000 20.46853  ?  255 GLY A N   1 
ATOM   1846 C  CA  . GLY A 1 255 ? 16.90128  16.43816  -13.23326 1.000 19.19970  ?  255 GLY A CA  1 
ATOM   1847 C  C   . GLY A 1 255 ? 15.86830  15.45453  -12.73334 1.000 27.01541  ?  255 GLY A C   1 
ATOM   1848 O  O   . GLY A 1 255 ? 14.75918  15.42105  -13.28045 1.000 49.13151  ?  255 GLY A O   1 
ATOM   1849 N  N   . PHE A 1 256 ? 16.19396  14.64706  -11.72548 1.000 23.79103  ?  256 PHE A N   1 
ATOM   1850 C  CA  . PHE A 1 256 ? 15.20574  13.74687  -11.14500 1.000 23.51728  ?  256 PHE A CA  1 
ATOM   1851 C  C   . PHE A 1 256 ? 14.09725  14.57088  -10.50803 1.000 24.66245  ?  256 PHE A C   1 
ATOM   1852 O  O   . PHE A 1 256 ? 14.35709  15.40151  -9.63281  1.000 27.76609  ?  256 PHE A O   1 
ATOM   1853 C  CB  . PHE A 1 256 ? 15.85107  12.82805  -10.10425 1.000 28.31788  ?  256 PHE A CB  1 
ATOM   1854 C  CG  . PHE A 1 256 ? 16.90601  11.90121  -10.65885 1.000 33.71880  ?  256 PHE A CG  1 
ATOM   1855 C  CD1 . PHE A 1 256 ? 17.19223  11.86276  -12.01534 1.000 27.17023  ?  256 PHE A CD1 1 
ATOM   1856 C  CD2 . PHE A 1 256 ? 17.60464  11.05551  -9.81219  1.000 30.69507  ?  256 PHE A CD2 1 
ATOM   1857 C  CE1 . PHE A 1 256 ? 18.16033  11.01251  -12.50904 1.000 23.88684  ?  256 PHE A CE1 1 
ATOM   1858 C  CE2 . PHE A 1 256 ? 18.57030  10.19841  -10.30334 1.000 18.22186  ?  256 PHE A CE2 1 
ATOM   1859 C  CZ  . PHE A 1 256 ? 18.85028  10.17954  -11.65169 1.000 19.73447  ?  256 PHE A CZ  1 
ATOM   1860 N  N   . PHE A 1 257 ? 12.86257  14.34979  -10.94546 1.000 21.70232  ?  257 PHE A N   1 
ATOM   1861 C  CA  . PHE A 1 257 ? 11.75213  15.19637  -10.54154 1.000 25.51504  ?  257 PHE A CA  1 
ATOM   1862 C  C   . PHE A 1 257 ? 10.68286  14.38282  -9.82478  1.000 26.63442  ?  257 PHE A C   1 
ATOM   1863 O  O   . PHE A 1 257 ? 10.58824  13.16136  -9.97726  1.000 26.16674  ?  257 PHE A O   1 
ATOM   1864 C  CB  . PHE A 1 257 ? 11.13956  15.92404  -11.74613 1.000 25.47815  ?  257 PHE A CB  1 
ATOM   1865 C  CG  . PHE A 1 257 ? 10.46645  15.01205  -12.72866 1.000 21.72448  ?  257 PHE A CG  1 
ATOM   1866 C  CD1 . PHE A 1 257 ? 11.19630  14.38999  -13.72682 1.000 22.92487  ?  257 PHE A CD1 1 
ATOM   1867 C  CD2 . PHE A 1 257 ? 9.10126   14.78426  -12.66049 1.000 17.45339  ?  257 PHE A CD2 1 
ATOM   1868 C  CE1 . PHE A 1 257 ? 10.57943  13.55234  -14.63472 1.000 26.21006  ?  257 PHE A CE1 1 
ATOM   1869 C  CE2 . PHE A 1 257 ? 8.47900   13.94757  -13.56352 1.000 22.29527  ?  257 PHE A CE2 1 
ATOM   1870 C  CZ  . PHE A 1 257 ? 9.21877   13.33059  -14.55271 1.000 28.35061  ?  257 PHE A CZ  1 
ATOM   1871 N  N   . GLU A 1 258 ? 9.87587   15.08583  -9.03786  1.000 28.27865  ?  258 GLU A N   1 
ATOM   1872 C  CA  . GLU A 1 258 ? 8.79080   14.49647  -8.27033  1.000 32.37165  ?  258 GLU A CA  1 
ATOM   1873 C  C   . GLU A 1 258 ? 7.44740   14.96697  -8.81201  1.000 32.95411  ?  258 GLU A C   1 
ATOM   1874 O  O   . GLU A 1 258 ? 7.36736   15.79965  -9.71857  1.000 25.47876  ?  258 GLU A O   1 
ATOM   1875 C  CB  . GLU A 1 258 ? 8.91722   14.86276  -6.78335  1.000 31.89133  ?  258 GLU A CB  1 
ATOM   1876 C  CG  . GLU A 1 258 ? 10.29250  14.60975  -6.19100  1.000 26.65817  ?  258 GLU A CG  1 
ATOM   1877 C  CD  . GLU A 1 258 ? 10.61218  13.13592  -6.05983  1.000 29.85413  ?  258 GLU A CD  1 
ATOM   1878 O  OE1 . GLU A 1 258 ? 9.67311   12.31252  -6.11193  1.000 27.28700  ?  258 GLU A OE1 1 
ATOM   1879 O  OE2 . GLU A 1 258 ? 11.80451  12.80111  -5.90256  1.000 37.74345  -1 258 GLU A OE2 1 
ATOM   1880 N  N   . LEU A 1 259 ? 6.37784   14.41236  -8.23658  1.000 36.04282  ?  259 LEU A N   1 
ATOM   1881 C  CA  . LEU A 1 259 ? 5.03573   14.77815  -8.67639  1.000 39.70328  ?  259 LEU A CA  1 
ATOM   1882 C  C   . LEU A 1 259 ? 4.69583   16.22120  -8.32322  1.000 36.24721  ?  259 LEU A C   1 
ATOM   1883 O  O   . LEU A 1 259 ? 3.87712   16.84639  -9.00633  1.000 35.10788  ?  259 LEU A O   1 
ATOM   1884 C  CB  . LEU A 1 259 ? 4.00435   13.82449  -8.07260  1.000 45.43946  ?  259 LEU A CB  1 
ATOM   1885 C  CG  . LEU A 1 259 ? 4.03442   12.38079  -8.57954  1.000 28.47620  ?  259 LEU A CG  1 
ATOM   1886 C  CD1 . LEU A 1 259 ? 2.86273   11.58737  -8.01831  1.000 26.27232  ?  259 LEU A CD1 1 
ATOM   1887 C  CD2 . LEU A 1 259 ? 4.03097   12.34457  -10.09855 1.000 24.13373  ?  259 LEU A CD2 1 
ATOM   1888 N  N   . ASP A 1 260 ? 5.30525   16.76511  -7.27029  1.000 36.80457  ?  260 ASP A N   1 
ATOM   1889 C  CA  . ASP A 1 260 ? 5.06105   18.14708  -6.87661  1.000 32.35870  ?  260 ASP A CA  1 
ATOM   1890 C  C   . ASP A 1 260 ? 5.87984   19.14598  -7.68560  1.000 28.24804  ?  260 ASP A C   1 
ATOM   1891 O  O   . ASP A 1 260 ? 5.69236   20.35558  -7.51872  1.000 34.66741  ?  260 ASP A O   1 
ATOM   1892 C  CB  . ASP A 1 260 ? 5.33318   18.33002  -5.37689  1.000 32.37687  ?  260 ASP A CB  1 
ATOM   1893 C  CG  . ASP A 1 260 ? 6.76717   17.99876  -4.98455  1.000 31.24350  ?  260 ASP A CG  1 
ATOM   1894 O  OD1 . ASP A 1 260 ? 7.59366   17.69874  -5.87057  1.000 36.28607  ?  260 ASP A OD1 1 
ATOM   1895 O  OD2 . ASP A 1 260 ? 7.06892   18.04113  -3.77347  1.000 27.68608  -1 260 ASP A OD2 1 
ATOM   1896 N  N   . GLY A 1 261 ? 6.77356   18.67207  -8.55319  1.000 27.82976  ?  261 GLY A N   1 
ATOM   1897 C  CA  . GLY A 1 261 ? 7.56883   19.52657  -9.40680  1.000 30.11766  ?  261 GLY A CA  1 
ATOM   1898 C  C   . GLY A 1 261 ? 8.99332   19.74912  -8.94482  1.000 30.17379  ?  261 GLY A C   1 
ATOM   1899 O  O   . GLY A 1 261 ? 9.76199   20.40287  -9.66183  1.000 31.41491  ?  261 GLY A O   1 
ATOM   1900 N  N   . THR A 1 262 ? 9.36505   19.23563  -7.77394  1.000 32.48678  ?  262 THR A N   1 
ATOM   1901 C  CA  . THR A 1 262 ? 10.72145  19.41422  -7.27200  1.000 32.07670  ?  262 THR A CA  1 
ATOM   1902 C  C   . THR A 1 262 ? 11.72348  18.72957  -8.19155  1.000 29.41942  ?  262 THR A C   1 
ATOM   1903 O  O   . THR A 1 262 ? 11.53293  17.57700  -8.58597  1.000 29.06868  ?  262 THR A O   1 
ATOM   1904 C  CB  . THR A 1 262 ? 10.84072  18.85031  -5.85465  1.000 29.19433  ?  262 THR A CB  1 
ATOM   1905 O  OG1 . THR A 1 262 ? 9.88905   19.49400  -4.99753  1.000 33.47892  ?  262 THR A OG1 1 
ATOM   1906 C  CG2 . THR A 1 262 ? 12.24347  19.07347  -5.30892  1.000 25.90381  ?  262 THR A CG2 1 
ATOM   1907 N  N   . VAL A 1 263 ? 12.79571  19.44278  -8.52910  1.000 28.68588  ?  263 VAL A N   1 
ATOM   1908 C  CA  . VAL A 1 263 ? 13.87292  18.91896  -9.36093  1.000 22.99220  ?  263 VAL A CA  1 
ATOM   1909 C  C   . VAL A 1 263 ? 15.15389  18.93196  -8.53976  1.000 26.56559  ?  263 VAL A C   1 
ATOM   1910 O  O   . VAL A 1 263 ? 15.54743  19.97790  -8.01019  1.000 32.45691  ?  263 VAL A O   1 
ATOM   1911 C  CB  . VAL A 1 263 ? 14.04264  19.73297  -10.65636 1.000 18.28053  ?  263 VAL A CB  1 
ATOM   1912 C  CG1 . VAL A 1 263 ? 15.23985  19.22881  -11.44381 1.000 19.27256  ?  263 VAL A CG1 1 
ATOM   1913 C  CG2 . VAL A 1 263 ? 12.77912  19.65800  -11.49839 1.000 25.67836  ?  263 VAL A CG2 1 
ATOM   1914 N  N   . HIS A 1 264 ? 15.80144  17.77670  -8.44102  1.000 27.98934  ?  264 HIS A N   1 
ATOM   1915 C  CA  . HIS A 1 264 ? 16.97320  17.59757  -7.59833  1.000 23.34217  ?  264 HIS A CA  1 
ATOM   1916 C  C   . HIS A 1 264 ? 18.25931  17.76784  -8.40080  1.000 26.28169  ?  264 HIS A C   1 
ATOM   1917 O  O   . HIS A 1 264 ? 18.26641  17.72045  -9.63368  1.000 27.00693  ?  264 HIS A O   1 
ATOM   1918 C  CB  . HIS A 1 264 ? 16.95310  16.21808  -6.93851  1.000 20.98228  ?  264 HIS A CB  1 
ATOM   1919 C  CG  . HIS A 1 264 ? 15.63762  15.85993  -6.32041  1.000 24.81005  ?  264 HIS A CG  1 
ATOM   1920 N  ND1 . HIS A 1 264 ? 15.17130  16.45073  -5.16598  1.000 31.01505  ?  264 HIS A ND1 1 
ATOM   1921 C  CD2 . HIS A 1 264 ? 14.69234  14.96451  -6.69262  1.000 24.52687  ?  264 HIS A CD2 1 
ATOM   1922 C  CE1 . HIS A 1 264 ? 13.99373  15.93778  -4.85597  1.000 26.75360  ?  264 HIS A CE1 1 
ATOM   1923 N  NE2 . HIS A 1 264 ? 13.68017  15.03383  -5.76652  1.000 23.58681  ?  264 HIS A NE2 1 
ATOM   1924 N  N   . ASP A 1 265 ? 19.35902  17.95933  -7.67367  1.000 21.65742  ?  265 ASP A N   1 
ATOM   1925 C  CA  . ASP A 1 265 ? 20.66834  18.15567  -8.27341  1.000 17.47424  ?  265 ASP A CA  1 
ATOM   1926 C  C   . ASP A 1 265 ? 21.36753  16.81255  -8.48804  1.000 15.06261  ?  265 ASP A C   1 
ATOM   1927 O  O   . ASP A 1 265 ? 20.85780  15.74897  -8.12678  1.000 18.25065  ?  265 ASP A O   1 
ATOM   1928 C  CB  . ASP A 1 265 ? 21.51165  19.08977  -7.40645  1.000 14.82095  ?  265 ASP A CB  1 
ATOM   1929 C  CG  . ASP A 1 265 ? 21.52596  18.67745  -5.94863  1.000 14.25676  ?  265 ASP A CG  1 
ATOM   1930 O  OD1 . ASP A 1 265 ? 22.12212  17.62783  -5.63122  1.000 26.76966  ?  265 ASP A OD1 1 
ATOM   1931 O  OD2 . ASP A 1 265 ? 20.94013  19.40322  -5.11866  1.000 11.54050  -1 265 ASP A OD2 1 
ATOM   1932 N  N   . ALA A 1 266 ? 22.56329  16.86820  -9.08404  1.000 13.25916  ?  266 ALA A N   1 
ATOM   1933 C  CA  . ALA A 1 266 ? 23.29361  15.64960  -9.42361  1.000 15.77083  ?  266 ALA A CA  1 
ATOM   1934 C  C   . ALA A 1 266 ? 23.67799  14.84795  -8.18649  1.000 19.39226  ?  266 ALA A C   1 
ATOM   1935 O  O   . ALA A 1 266 ? 23.73053  13.61179  -8.23894  1.000 21.25627  ?  266 ALA A O   1 
ATOM   1936 C  CB  . ALA A 1 266 ? 24.54081  15.99517  -10.23768 1.000 11.27113  ?  266 ALA A CB  1 
ATOM   1937 N  N   . GLU A 1 267 ? 23.95798  15.52748  -7.07234  1.000 21.41435  ?  267 GLU A N   1 
ATOM   1938 C  CA  . GLU A 1 267 ? 24.33476  14.82222  -5.85206  1.000 18.43663  ?  267 GLU A CA  1 
ATOM   1939 C  C   . GLU A 1 267 ? 23.19786  13.93927  -5.35344  1.000 21.43260  ?  267 GLU A C   1 
ATOM   1940 O  O   . GLU A 1 267 ? 23.43683  12.84369  -4.83171  1.000 26.70660  ?  267 GLU A O   1 
ATOM   1941 C  CB  . GLU A 1 267 ? 24.75486  15.82338  -4.77734  1.000 22.20318  ?  267 GLU A CB  1 
ATOM   1942 C  CG  . GLU A 1 267 ? 25.37481  15.19021  -3.54552  1.000 21.29852  ?  267 GLU A CG  1 
ATOM   1943 C  CD  . GLU A 1 267 ? 25.85146  16.22327  -2.54530  1.000 25.57795  ?  267 GLU A CD  1 
ATOM   1944 O  OE1 . GLU A 1 267 ? 25.53663  17.41820  -2.73048  1.000 18.66427  ?  267 GLU A OE1 1 
ATOM   1945 O  OE2 . GLU A 1 267 ? 26.54281  15.84230  -1.57740  1.000 24.00505  -1 267 GLU A OE2 1 
ATOM   1946 N  N   . PHE A 1 268 ? 21.95192  14.39830  -5.50487  1.000 18.42441  ?  268 PHE A N   1 
ATOM   1947 C  CA  . PHE A 1 268 ? 20.81314  13.57019  -5.12008  1.000 20.90005  ?  268 PHE A CA  1 
ATOM   1948 C  C   . PHE A 1 268 ? 20.75953  12.29005  -5.94209  1.000 24.52027  ?  268 PHE A C   1 
ATOM   1949 O  O   . PHE A 1 268 ? 20.51290  11.20659  -5.39981  1.000 23.50707  ?  268 PHE A O   1 
ATOM   1950 C  CB  . PHE A 1 268 ? 19.50853  14.35116  -5.27480  1.000 17.07133  ?  268 PHE A CB  1 
ATOM   1951 C  CG  . PHE A 1 268 ? 18.27353  13.50435  -5.11386  1.000 18.19730  ?  268 PHE A CG  1 
ATOM   1952 C  CD1 . PHE A 1 268 ? 17.76064  13.23775  -3.85606  1.000 20.16712  ?  268 PHE A CD1 1 
ATOM   1953 C  CD2 . PHE A 1 268 ? 17.62820  12.97125  -6.22052  1.000 22.64067  ?  268 PHE A CD2 1 
ATOM   1954 C  CE1 . PHE A 1 268 ? 16.62808  12.45864  -3.70414  1.000 20.47119  ?  268 PHE A CE1 1 
ATOM   1955 C  CE2 . PHE A 1 268 ? 16.49671  12.19200  -6.07436  1.000 20.48109  ?  268 PHE A CE2 1 
ATOM   1956 C  CZ  . PHE A 1 268 ? 15.99579  11.93621  -4.81479  1.000 19.14340  ?  268 PHE A CZ  1 
ATOM   1957 N  N   . GLY A 1 269 ? 20.96688  12.39741  -7.25623  1.000 23.09560  ?  269 GLY A N   1 
ATOM   1958 C  CA  . GLY A 1 269 ? 20.97583  11.20693  -8.08990  1.000 22.79687  ?  269 GLY A CA  1 
ATOM   1959 C  C   . GLY A 1 269 ? 22.11103  10.26678  -7.73970  1.000 23.87463  ?  269 GLY A C   1 
ATOM   1960 O  O   . GLY A 1 269 ? 21.93717  9.04313   -7.71741  1.000 29.53948  ?  269 GLY A O   1 
ATOM   1961 N  N   . LEU A 1 270 ? 23.28791  10.82723  -7.45196  1.000 19.06480  ?  270 LEU A N   1 
ATOM   1962 C  CA  . LEU A 1 270 ? 24.41089  10.00198  -7.02413  1.000 20.62169  ?  270 LEU A CA  1 
ATOM   1963 C  C   . LEU A 1 270 ? 24.08407  9.26205   -5.73377  1.000 23.34853  ?  270 LEU A C   1 
ATOM   1964 O  O   . LEU A 1 270 ? 24.38463  8.07134   -5.60031  1.000 27.54214  ?  270 LEU A O   1 
ATOM   1965 C  CB  . LEU A 1 270 ? 25.65885  10.86582  -6.84799  1.000 18.80969  ?  270 LEU A CB  1 
ATOM   1966 C  CG  . LEU A 1 270 ? 26.96254  10.11918  -6.56823  1.000 14.79122  ?  270 LEU A CG  1 
ATOM   1967 C  CD1 . LEU A 1 270 ? 27.32160  9.22672   -7.74267  1.000 17.33260  ?  270 LEU A CD1 1 
ATOM   1968 C  CD2 . LEU A 1 270 ? 28.08470  11.09806  -6.27504  1.000 19.62766  ?  270 LEU A CD2 1 
ATOM   1969 N  N   . ASN A 1 271 ? 23.45164  9.94726   -4.77786  1.000 19.47819  ?  271 ASN A N   1 
ATOM   1970 C  CA  . ASN A 1 271 ? 23.09937  9.30576   -3.51417  1.000 25.97401  ?  271 ASN A CA  1 
ATOM   1971 C  C   . ASN A 1 271 ? 22.02455  8.24116   -3.70314  1.000 31.93145  ?  271 ASN A C   1 
ATOM   1972 O  O   . ASN A 1 271 ? 22.05773  7.19770   -3.04178  1.000 34.94974  ?  271 ASN A O   1 
ATOM   1973 C  CB  . ASN A 1 271 ? 22.64495  10.35501  -2.50179  1.000 27.87443  ?  271 ASN A CB  1 
ATOM   1974 C  CG  . ASN A 1 271 ? 23.74724  10.74852  -1.54131  1.000 30.90505  ?  271 ASN A CG  1 
ATOM   1975 O  OD1 . ASN A 1 271 ? 24.46906  9.89441   -1.02471  1.000 27.90429  ?  271 ASN A OD1 1 
ATOM   1976 N  ND2 . ASN A 1 271 ? 23.88749  12.04679  -1.30008  1.000 33.81059  ?  271 ASN A ND2 1 
ATOM   1977 N  N   . LEU A 1 272 ? 21.05480  8.49096   -4.58525  1.000 30.31051  ?  272 LEU A N   1 
ATOM   1978 C  CA  . LEU A 1 272 ? 20.03177  7.48700   -4.86556  1.000 28.31197  ?  272 LEU A CA  1 
ATOM   1979 C  C   . LEU A 1 272 ? 20.65736  6.23252   -5.46503  1.000 26.01612  ?  272 LEU A C   1 
ATOM   1980 O  O   . LEU A 1 272 ? 20.35898  5.10430   -5.04283  1.000 25.00995  ?  272 LEU A O   1 
ATOM   1981 C  CB  . LEU A 1 272 ? 18.97543  8.07384   -5.80480  1.000 25.62010  ?  272 LEU A CB  1 
ATOM   1982 C  CG  . LEU A 1 272 ? 17.71627  7.25510   -6.09936  1.000 29.93423  ?  272 LEU A CG  1 
ATOM   1983 C  CD1 . LEU A 1 272 ? 16.86465  7.10203   -4.84943  1.000 33.06090  ?  272 LEU A CD1 1 
ATOM   1984 C  CD2 . LEU A 1 272 ? 16.91276  7.89601   -7.22159  1.000 23.33696  ?  272 LEU A CD2 1 
ATOM   1985 N  N   . TYR A 1 273 ? 21.55524  6.41690   -6.43809  1.000 24.94354  ?  273 TYR A N   1 
ATOM   1986 C  CA  . TYR A 1 273 ? 22.26540  5.28037   -7.01467  1.000 24.82615  ?  273 TYR A CA  1 
ATOM   1987 C  C   . TYR A 1 273 ? 23.09912  4.56158   -5.96199  1.000 28.12160  ?  273 TYR A C   1 
ATOM   1988 O  O   . TYR A 1 273 ? 23.16109  3.32779   -5.94635  1.000 24.68047  ?  273 TYR A O   1 
ATOM   1989 C  CB  . TYR A 1 273 ? 23.15210  5.74095   -8.17188  1.000 23.16518  ?  273 TYR A CB  1 
ATOM   1990 C  CG  . TYR A 1 273 ? 22.41151  5.99392   -9.46529  1.000 21.06810  ?  273 TYR A CG  1 
ATOM   1991 C  CD1 . TYR A 1 273 ? 21.03562  5.82697   -9.54762  1.000 19.74723  ?  273 TYR A CD1 1 
ATOM   1992 C  CD2 . TYR A 1 273 ? 23.09367  6.38506   -10.60988 1.000 19.40145  ?  273 TYR A CD2 1 
ATOM   1993 C  CE1 . TYR A 1 273 ? 20.35909  6.05406   -10.73084 1.000 19.24052  ?  273 TYR A CE1 1 
ATOM   1994 C  CE2 . TYR A 1 273 ? 22.42645  6.61208   -11.79705 1.000 16.73432  ?  273 TYR A CE2 1 
ATOM   1995 C  CZ  . TYR A 1 273 ? 21.05997  6.44523   -11.85173 1.000 17.96643  ?  273 TYR A CZ  1 
ATOM   1996 O  OH  . TYR A 1 273 ? 20.39322  6.67041   -13.03255 1.000 17.82833  ?  273 TYR A OH  1 
ATOM   1997 N  N   . LYS A 1 274 ? 23.75163  5.31955   -5.07720  1.000 22.75475  ?  274 LYS A N   1 
ATOM   1998 C  CA  . LYS A 1 274 ? 24.58763  4.71782   -4.04384  1.000 20.85417  ?  274 LYS A CA  1 
ATOM   1999 C  C   . LYS A 1 274 ? 23.76111  3.88337   -3.07316  1.000 22.33161  ?  274 LYS A C   1 
ATOM   2000 O  O   . LYS A 1 274 ? 24.16816  2.78057   -2.69095  1.000 22.18654  ?  274 LYS A O   1 
ATOM   2001 C  CB  . LYS A 1 274 ? 25.35585  5.81493   -3.30671  1.000 21.48888  ?  274 LYS A CB  1 
ATOM   2002 C  CG  . LYS A 1 274 ? 26.26225  5.33112   -2.19064  1.000 23.89287  ?  274 LYS A CG  1 
ATOM   2003 C  CD  . LYS A 1 274 ? 27.20500  6.44348   -1.75284  1.000 17.04092  ?  274 LYS A CD  1 
ATOM   2004 C  CE  . LYS A 1 274 ? 27.83339  6.14791   -0.40314  1.000 21.48739  ?  274 LYS A CE  1 
ATOM   2005 N  NZ  . LYS A 1 274 ? 26.81699  6.16364   0.68520   1.000 29.86007  ?  274 LYS A NZ  1 
ATOM   2006 N  N   . SER A 1 275 ? 22.59683  4.39235   -2.66223  1.000 27.39325  ?  275 SER A N   1 
ATOM   2007 C  CA  . SER A 1 275 ? 21.73580  3.63110   -1.76145  1.000 29.96606  ?  275 SER A CA  1 
ATOM   2008 C  C   . SER A 1 275 ? 21.22326  2.36266   -2.43219  1.000 30.85543  ?  275 SER A C   1 
ATOM   2009 O  O   . SER A 1 275 ? 21.20421  1.28855   -1.81427  1.000 31.19883  ?  275 SER A O   1 
ATOM   2010 C  CB  . SER A 1 275 ? 20.56918  4.49628   -1.28111  1.000 28.73158  ?  275 SER A CB  1 
ATOM   2011 O  OG  . SER A 1 275 ? 19.68844  4.81615   -2.34368  1.000 28.48056  ?  275 SER A OG  1 
ATOM   2012 N  N   . VAL A 1 276 ? 20.81419  2.46159   -3.70170  1.000 29.31486  ?  276 VAL A N   1 
ATOM   2013 C  CA  . VAL A 1 276 ? 20.35281  1.27114   -4.41361  1.000 28.20857  ?  276 VAL A CA  1 
ATOM   2014 C  C   . VAL A 1 276 ? 21.47821  0.25047   -4.53346  1.000 24.93197  ?  276 VAL A C   1 
ATOM   2015 O  O   . VAL A 1 276 ? 21.27138  -0.95234  -4.32581  1.000 24.12844  ?  276 VAL A O   1 
ATOM   2016 C  CB  . VAL A 1 276 ? 19.78499  1.65454   -5.79212  1.000 30.81294  ?  276 VAL A CB  1 
ATOM   2017 C  CG1 . VAL A 1 276 ? 19.46487  0.40630   -6.60158  1.000 22.18192  ?  276 VAL A CG1 1 
ATOM   2018 C  CG2 . VAL A 1 276 ? 18.54570  2.50811   -5.62329  1.000 27.56642  ?  276 VAL A CG2 1 
ATOM   2019 N  N   . THR A 1 277 ? 22.68721  0.71390   -4.86180  1.000 22.62199  ?  277 THR A N   1 
ATOM   2020 C  CA  . THR A 1 277 ? 23.82091  -0.19166  -5.01437  1.000 25.03891  ?  277 THR A CA  1 
ATOM   2021 C  C   . THR A 1 277 ? 24.17672  -0.86656  -3.69625  1.000 24.76697  ?  277 THR A C   1 
ATOM   2022 O  O   . THR A 1 277 ? 24.47586  -2.06444  -3.66819  1.000 22.34988  ?  277 THR A O   1 
ATOM   2023 C  CB  . THR A 1 277 ? 25.02605  0.56898   -5.56858  1.000 21.52989  ?  277 THR A CB  1 
ATOM   2024 O  OG1 . THR A 1 277 ? 24.70317  1.09826   -6.85972  1.000 20.32933  ?  277 THR A OG1 1 
ATOM   2025 C  CG2 . THR A 1 277 ? 26.23483  -0.34977  -5.69078  1.000 17.96036  ?  277 THR A CG2 1 
ATOM   2026 N  N   . GLU A 1 278 ? 24.15637  -0.11488  -2.59305  1.000 27.29878  ?  278 GLU A N   1 
ATOM   2027 C  CA  . GLU A 1 278 ? 24.48025  -0.70354  -1.29729  1.000 22.84164  ?  278 GLU A CA  1 
ATOM   2028 C  C   . GLU A 1 278 ? 23.42592  -1.71768  -0.86796  1.000 25.48453  ?  278 GLU A C   1 
ATOM   2029 O  O   . GLU A 1 278 ? 23.76492  -2.78695  -0.34562  1.000 26.63745  ?  278 GLU A O   1 
ATOM   2030 C  CB  . GLU A 1 278 ? 24.64825  0.39729   -0.25082  1.000 23.17879  ?  278 GLU A CB  1 
ATOM   2031 C  CG  . GLU A 1 278 ? 25.91383  1.22107   -0.44941  1.000 24.81768  ?  278 GLU A CG  1 
ATOM   2032 C  CD  . GLU A 1 278 ? 25.99385  2.41692   0.47616   1.000 26.03649  ?  278 GLU A CD  1 
ATOM   2033 O  OE1 . GLU A 1 278 ? 24.98106  2.72989   1.13581   1.000 41.33811  ?  278 GLU A OE1 1 
ATOM   2034 O  OE2 . GLU A 1 278 ? 27.07168  3.04473   0.54295   1.000 22.08643  -1 278 GLU A OE2 1 
ATOM   2035 N  N   . GLU A 1 279 ? 22.14382  -1.41260  -1.09364  1.000 30.83713  ?  279 GLU A N   1 
ATOM   2036 C  CA  . GLU A 1 279 ? 21.09685  -2.38787  -0.79857  1.000 29.61032  ?  279 GLU A CA  1 
ATOM   2037 C  C   . GLU A 1 279 ? 21.26858  -3.65123  -1.63542  1.000 26.68857  ?  279 GLU A C   1 
ATOM   2038 O  O   . GLU A 1 279 ? 21.14343  -4.77207  -1.12185  1.000 23.96921  ?  279 GLU A O   1 
ATOM   2039 C  CB  . GLU A 1 279 ? 19.72084  -1.76394  -1.03834  1.000 33.74191  ?  279 GLU A CB  1 
ATOM   2040 C  CG  . GLU A 1 279 ? 18.56604  -2.75542  -1.02733  1.000 40.00133  ?  279 GLU A CG  1 
ATOM   2041 C  CD  . GLU A 1 279 ? 18.31308  -3.35135  0.34384   1.000 45.04271  ?  279 GLU A CD  1 
ATOM   2042 O  OE1 . GLU A 1 279 ? 18.64254  -2.69198  1.35256   1.000 43.07790  ?  279 GLU A OE1 1 
ATOM   2043 O  OE2 . GLU A 1 279 ? 17.78462  -4.48143  0.41207   1.000 40.45142  -1 279 GLU A OE2 1 
ATOM   2044 N  N   . PHE A 1 280 ? 21.57061  -3.48855  -2.92647  1.000 30.32102  ?  280 PHE A N   1 
ATOM   2045 C  CA  . PHE A 1 280 ? 21.74944  -4.64185  -3.80182  1.000 26.30993  ?  280 PHE A CA  1 
ATOM   2046 C  C   . PHE A 1 280 ? 22.95598  -5.47495  -3.38387  1.000 26.85955  ?  280 PHE A C   1 
ATOM   2047 O  O   . PHE A 1 280 ? 22.90791  -6.71002  -3.41703  1.000 29.92873  ?  280 PHE A O   1 
ATOM   2048 C  CB  . PHE A 1 280 ? 21.88806  -4.17428  -5.24951  1.000 23.90618  ?  280 PHE A CB  1 
ATOM   2049 C  CG  . PHE A 1 280 ? 21.72267  -5.27054  -6.25764  1.000 24.84171  ?  280 PHE A CG  1 
ATOM   2050 C  CD1 . PHE A 1 280 ? 20.46028  -5.67915  -6.65134  1.000 19.50759  ?  280 PHE A CD1 1 
ATOM   2051 C  CD2 . PHE A 1 280 ? 22.82799  -5.88974  -6.81577  1.000 25.02732  ?  280 PHE A CD2 1 
ATOM   2052 C  CE1 . PHE A 1 280 ? 20.30351  -6.68582  -7.57849  1.000 19.52775  ?  280 PHE A CE1 1 
ATOM   2053 C  CE2 . PHE A 1 280 ? 22.67677  -6.89801  -7.74571  1.000 23.34539  ?  280 PHE A CE2 1 
ATOM   2054 C  CZ  . PHE A 1 280 ? 21.41222  -7.29599  -8.12804  1.000 22.75902  ?  280 PHE A CZ  1 
ATOM   2055 N  N   . GLN A 1 281 ? 24.05149  -4.81601  -2.99700  1.000 25.81393  ?  281 GLN A N   1 
ATOM   2056 C  CA  . GLN A 1 281 ? 25.22269  -5.53690  -2.50812  1.000 23.92459  ?  281 GLN A CA  1 
ATOM   2057 C  C   . GLN A 1 281 ? 24.90566  -6.29224  -1.22512  1.000 22.32103  ?  281 GLN A C   1 
ATOM   2058 O  O   . GLN A 1 281 ? 25.38679  -7.41310  -1.02103  1.000 24.90843  ?  281 GLN A O   1 
ATOM   2059 C  CB  . GLN A 1 281 ? 26.38470  -4.56841  -2.28540  1.000 25.17144  ?  281 GLN A CB  1 
ATOM   2060 C  CG  . GLN A 1 281 ? 27.04205  -4.06672  -3.56051  1.000 22.03069  ?  281 GLN A CG  1 
ATOM   2061 C  CD  . GLN A 1 281 ? 28.06650  -2.98010  -3.29435  1.000 20.15978  ?  281 GLN A CD  1 
ATOM   2062 O  OE1 . GLN A 1 281 ? 29.10009  -2.90870  -3.95823  1.000 22.30299  ?  281 GLN A OE1 1 
ATOM   2063 N  NE2 . GLN A 1 281 ? 27.78047  -2.12283  -2.32074  1.000 17.82289  ?  281 GLN A NE2 1 
ATOM   2064 N  N   . ARG A 1 282 ? 24.10580  -5.68903  -0.34143  1.000 26.38506  ?  282 ARG A N   1 
ATOM   2065 C  CA  . ARG A 1 282 ? 23.68343  -6.39400  0.86414   1.000 23.44444  ?  282 ARG A CA  1 
ATOM   2066 C  C   . ARG A 1 282 ? 22.86793  -7.63090  0.51634   1.000 20.26677  ?  282 ARG A C   1 
ATOM   2067 O  O   . ARG A 1 282 ? 23.02247  -8.68314  1.14692   1.000 28.59260  ?  282 ARG A O   1 
ATOM   2068 C  CB  . ARG A 1 282 ? 22.88045  -5.46294  1.77401   1.000 28.98217  ?  282 ARG A CB  1 
ATOM   2069 C  CG  . ARG A 1 282 ? 23.72073  -4.42770  2.50401   1.000 38.28617  ?  282 ARG A CG  1 
ATOM   2070 C  CD  . ARG A 1 282 ? 22.91256  -3.70281  3.56864   1.000 27.16257  ?  282 ARG A CD  1 
ATOM   2071 N  NE  . ARG A 1 282 ? 21.86622  -2.86442  2.99628   1.000 29.07497  ?  282 ARG A NE  1 
ATOM   2072 C  CZ  . ARG A 1 282 ? 22.03561  -1.59951  2.63607   1.000 39.66801  ?  282 ARG A CZ  1 
ATOM   2073 N  NH1 . ARG A 1 282 ? 23.20833  -0.99852  2.75414   1.000 40.38072  ?  282 ARG A NH1 1 
ATOM   2074 N  NH2 . ARG A 1 282 ? 21.00209  -0.91960  2.14752   1.000 46.01588  ?  282 ARG A NH2 1 
ATOM   2075 N  N   . GLU A 1 283 ? 21.99174  -7.52482  -0.48443  1.000 21.23505  ?  283 GLU A N   1 
ATOM   2076 C  CA  . GLU A 1 283 ? 21.16172  -8.66949  -0.84873  1.000 28.35677  ?  283 GLU A CA  1 
ATOM   2077 C  C   . GLU A 1 283 ? 21.97672  -9.77257  -1.51685  1.000 29.87031  ?  283 GLU A C   1 
ATOM   2078 O  O   . GLU A 1 283 ? 21.79244  -10.95647 -1.21080  1.000 36.93919  ?  283 GLU A O   1 
ATOM   2079 C  CB  . GLU A 1 283 ? 20.02210  -8.22260  -1.76041  1.000 23.98427  ?  283 GLU A CB  1 
ATOM   2080 C  CG  . GLU A 1 283 ? 18.96520  -7.38994  -1.06447  1.000 30.36668  ?  283 GLU A CG  1 
ATOM   2081 C  CD  . GLU A 1 283 ? 17.95824  -6.82787  -2.03798  1.000 43.18170  ?  283 GLU A CD  1 
ATOM   2082 O  OE1 . GLU A 1 283 ? 18.17205  -6.99521  -3.25543  1.000 43.69865  ?  283 GLU A OE1 1 
ATOM   2083 O  OE2 . GLU A 1 283 ? 16.96035  -6.22326  -1.59149  1.000 44.47426  -1 283 GLU A OE2 1 
ATOM   2084 N  N   . TYR A 1 284 ? 22.87757  -9.41255  -2.42757  1.000 23.69179  ?  284 TYR A N   1 
ATOM   2085 C  CA  . TYR A 1 284 ? 23.59217  -10.39214 -3.24824  1.000 22.65934  ?  284 TYR A CA  1 
ATOM   2086 C  C   . TYR A 1 284 ? 25.09661  -10.28328 -3.04168  1.000 26.81273  ?  284 TYR A C   1 
ATOM   2087 O  O   . TYR A 1 284 ? 25.75655  -9.44383  -3.68081  1.000 24.88774  ?  284 TYR A O   1 
ATOM   2088 C  CB  . TYR A 1 284 ? 23.23366  -10.20937 -4.72169  1.000 20.93834  ?  284 TYR A CB  1 
ATOM   2089 C  CG  . TYR A 1 284 ? 21.76696  -10.44295 -5.00476  1.000 22.00398  ?  284 TYR A CG  1 
ATOM   2090 C  CD1 . TYR A 1 284 ? 21.27268  -11.72729 -5.18510  1.000 27.90604  ?  284 TYR A CD1 1 
ATOM   2091 C  CD2 . TYR A 1 284 ? 20.87383  -9.38234  -5.07614  1.000 28.99139  ?  284 TYR A CD2 1 
ATOM   2092 C  CE1 . TYR A 1 284 ? 19.93290  -11.95004 -5.43951  1.000 32.98733  ?  284 TYR A CE1 1 
ATOM   2093 C  CE2 . TYR A 1 284 ? 19.52978  -9.59537  -5.32821  1.000 30.64582  ?  284 TYR A CE2 1 
ATOM   2094 C  CZ  . TYR A 1 284 ? 19.06606  -10.88157 -5.50910  1.000 27.32361  ?  284 TYR A CZ  1 
ATOM   2095 O  OH  . TYR A 1 284 ? 17.73176  -11.10163 -5.76080  1.000 29.62106  ?  284 TYR A OH  1 
ATOM   2096 N  N   . PRO A 1 285 ? 25.68122  -11.10305 -2.16287  1.000 25.61715  ?  285 PRO A N   1 
ATOM   2097 C  CA  . PRO A 1 285 ? 27.13461  -11.02549 -1.93265  1.000 24.66335  ?  285 PRO A CA  1 
ATOM   2098 C  C   . PRO A 1 285 ? 27.97427  -11.35947 -3.15335  1.000 27.33051  ?  285 PRO A C   1 
ATOM   2099 O  O   . PRO A 1 285 ? 29.11320  -10.88608 -3.24950  1.000 26.50977  ?  285 PRO A O   1 
ATOM   2100 C  CB  . PRO A 1 285 ? 27.36344  -12.03927 -0.80192  1.000 24.60479  ?  285 PRO A CB  1 
ATOM   2101 C  CG  . PRO A 1 285 ? 26.02059  -12.19842 -0.15035  1.000 24.72891  ?  285 PRO A CG  1 
ATOM   2102 C  CD  . PRO A 1 285 ? 25.02607  -12.06012 -1.25779  1.000 21.53432  ?  285 PRO A CD  1 
ATOM   2103 N  N   . ASP A 1 286 ? 27.45968  -12.16427 -4.08657  1.000 29.79277  ?  286 ASP A N   1 
ATOM   2104 C  CA  . ASP A 1 286 ? 28.22327  -12.49039 -5.28606  1.000 29.57633  ?  286 ASP A CA  1 
ATOM   2105 C  C   . ASP A 1 286 ? 28.41153  -11.29092 -6.20500  1.000 37.83344  ?  286 ASP A C   1 
ATOM   2106 O  O   . ASP A 1 286 ? 29.24348  -11.35424 -7.11703  1.000 38.40365  ?  286 ASP A O   1 
ATOM   2107 C  CB  . ASP A 1 286 ? 27.54659  -13.63183 -6.05077  1.000 24.83767  ?  286 ASP A CB  1 
ATOM   2108 C  CG  . ASP A 1 286 ? 26.10926  -13.31711 -6.42478  1.000 22.01436  ?  286 ASP A CG  1 
ATOM   2109 O  OD1 . ASP A 1 286 ? 25.89201  -12.52507 -7.36609  1.000 22.82833  ?  286 ASP A OD1 1 
ATOM   2110 O  OD2 . ASP A 1 286 ? 25.19440  -13.86838 -5.77870  1.000 20.43164  -1 286 ASP A OD2 1 
ATOM   2111 N  N   . PHE A 1 287 ? 27.66610  -10.21136 -5.98699  1.000 37.57071  ?  287 PHE A N   1 
ATOM   2112 C  CA  . PHE A 1 287 ? 27.80158  -9.00697  -6.79081  1.000 32.53763  ?  287 PHE A CA  1 
ATOM   2113 C  C   . PHE A 1 287 ? 28.98024  -8.17494  -6.30035  1.000 30.57402  ?  287 PHE A C   1 
ATOM   2114 O  O   . PHE A 1 287 ? 29.18193  -8.00609  -5.09405  1.000 34.61498  ?  287 PHE A O   1 
ATOM   2115 C  CB  . PHE A 1 287 ? 26.51121  -8.18895  -6.72824  1.000 30.76132  ?  287 PHE A CB  1 
ATOM   2116 C  CG  . PHE A 1 287 ? 26.33814  -7.23539  -7.87275  1.000 26.63343  ?  287 PHE A CG  1 
ATOM   2117 C  CD1 . PHE A 1 287 ? 26.01339  -7.70251  -9.13531  1.000 28.46643  ?  287 PHE A CD1 1 
ATOM   2118 C  CD2 . PHE A 1 287 ? 26.48229  -5.87190  -7.68415  1.000 27.62879  ?  287 PHE A CD2 1 
ATOM   2119 C  CE1 . PHE A 1 287 ? 25.84754  -6.82879  -10.19170 1.000 25.09724  ?  287 PHE A CE1 1 
ATOM   2120 C  CE2 . PHE A 1 287 ? 26.31705  -4.99165  -8.73669  1.000 29.81714  ?  287 PHE A CE2 1 
ATOM   2121 C  CZ  . PHE A 1 287 ? 25.99925  -5.47093  -9.99197  1.000 27.56052  ?  287 PHE A CZ  1 
ATOM   2122 N  N   . ILE A 1 288 ? 29.76367  -7.65692  -7.24559  1.000 21.09781  ?  288 ILE A N   1 
ATOM   2123 C  CA  . ILE A 1 288 ? 30.93323  -6.86060  -6.88797  1.000 24.72938  ?  288 ILE A CA  1 
ATOM   2124 C  C   . ILE A 1 288 ? 30.53206  -5.42944  -6.54906  1.000 26.99254  ?  288 ILE A C   1 
ATOM   2125 O  O   . ILE A 1 288 ? 30.94969  -4.88030  -5.52306  1.000 28.56737  ?  288 ILE A O   1 
ATOM   2126 C  CB  . ILE A 1 288 ? 31.97761  -6.90905  -8.01782  1.000 26.49482  ?  288 ILE A CB  1 
ATOM   2127 C  CG1 . ILE A 1 288 ? 32.47739  -8.34338  -8.20769  1.000 25.66657  ?  288 ILE A CG1 1 
ATOM   2128 C  CG2 . ILE A 1 288 ? 33.13485  -5.97004  -7.71429  1.000 22.78405  ?  288 ILE A CG2 1 
ATOM   2129 C  CD1 . ILE A 1 288 ? 33.48521  -8.50326  -9.32125  1.000 18.01887  ?  288 ILE A CD1 1 
ATOM   2130 N  N   . GLY A 1 289 ? 29.72566  -4.80151  -7.39608  1.000 22.65356  ?  289 GLY A N   1 
ATOM   2131 C  CA  . GLY A 1 289 ? 29.20537  -3.48599  -7.10402  1.000 19.84382  ?  289 GLY A CA  1 
ATOM   2132 C  C   . GLY A 1 289 ? 29.08546  -2.64795  -8.35687  1.000 18.18337  ?  289 GLY A C   1 
ATOM   2133 O  O   . GLY A 1 289 ? 29.20682  -3.13994  -9.47773  1.000 20.00862  ?  289 GLY A O   1 
ATOM   2134 N  N   . ALA A 1 290 ? 28.83779  -1.35511  -8.14865  1.000 17.05299  ?  290 ALA A N   1 
ATOM   2135 C  CA  . ALA A 1 290 ? 28.68311  -0.39605  -9.23110  1.000 15.22490  ?  290 ALA A CA  1 
ATOM   2136 C  C   . ALA A 1 290 ? 29.39243  0.89899   -8.86606  1.000 17.66081  ?  290 ALA A C   1 
ATOM   2137 O  O   . ALA A 1 290 ? 29.51922  1.24390   -7.68816  1.000 18.91060  ?  290 ALA A O   1 
ATOM   2138 C  CB  . ALA A 1 290 ? 27.20481  -0.11200  -9.52684  1.000 14.75157  ?  290 ALA A CB  1 
ATOM   2139 N  N   . LYS A 1 291 ? 29.86500  1.60800   -9.89113  1.000 15.73496  ?  291 LYS A N   1 
ATOM   2140 C  CA  . LYS A 1 291 ? 30.45095  2.93190   -9.73003  1.000 16.77098  ?  291 LYS A CA  1 
ATOM   2141 C  C   . LYS A 1 291 ? 29.96874  3.81381   -10.87373 1.000 16.32277  ?  291 LYS A C   1 
ATOM   2142 O  O   . LYS A 1 291 ? 29.68815  3.32642   -11.97074 1.000 13.35510  ?  291 LYS A O   1 
ATOM   2143 C  CB  . LYS A 1 291 ? 31.98601  2.87291   -9.68326  1.000 16.94406  ?  291 LYS A CB  1 
ATOM   2144 C  CG  . LYS A 1 291 ? 32.52594  1.95281   -8.59217  1.000 21.27059  ?  291 LYS A CG  1 
ATOM   2145 C  CD  . LYS A 1 291 ? 33.99389  2.19433   -8.29443  1.000 21.92244  ?  291 LYS A CD  1 
ATOM   2146 C  CE  . LYS A 1 291 ? 34.50833  1.18916   -7.27864  1.000 18.71177  ?  291 LYS A CE  1 
ATOM   2147 N  NZ  . LYS A 1 291 ? 33.60939  1.08668   -6.09574  1.000 19.27775  ?  291 LYS A NZ  1 
ATOM   2148 N  N   . ILE A 1 292 ? 29.87302  5.11725   -10.61339 1.000 20.19818  ?  292 ILE A N   1 
ATOM   2149 C  CA  . ILE A 1 292 ? 29.14126  6.03553   -11.47961 1.000 24.74564  ?  292 ILE A CA  1 
ATOM   2150 C  C   . ILE A 1 292 ? 30.08161  7.09359   -12.04220 1.000 18.70320  ?  292 ILE A C   1 
ATOM   2151 O  O   . ILE A 1 292 ? 30.90894  7.65883   -11.31857 1.000 18.91958  ?  292 ILE A O   1 
ATOM   2152 C  CB  . ILE A 1 292 ? 27.96641  6.69905   -10.72995 1.000 19.46669  ?  292 ILE A CB  1 
ATOM   2153 C  CG1 . ILE A 1 292 ? 27.03493  5.63330   -10.15407 1.000 13.60351  ?  292 ILE A CG1 1 
ATOM   2154 C  CG2 . ILE A 1 292 ? 27.18922  7.62569   -11.65465 1.000 14.72326  ?  292 ILE A CG2 1 
ATOM   2155 C  CD1 . ILE A 1 292 ? 26.43669  4.71837   -11.19531 1.000 16.11372  ?  292 ILE A CD1 1 
ATOM   2156 N  N   . ILE A 1 293 ? 29.93041  7.36837   -13.33672 1.000 16.59924  ?  293 ILE A N   1 
ATOM   2157 C  CA  . ILE A 1 293 ? 30.64368  8.42968   -14.03671 1.000 21.82561  ?  293 ILE A CA  1 
ATOM   2158 C  C   . ILE A 1 293 ? 29.62663  9.47393   -14.47842 1.000 24.01128  ?  293 ILE A C   1 
ATOM   2159 O  O   . ILE A 1 293 ? 28.52644  9.12809   -14.92271 1.000 22.98559  ?  293 ILE A O   1 
ATOM   2160 C  CB  . ILE A 1 293 ? 31.41933  7.87376   -15.24728 1.000 19.24731  ?  293 ILE A CB  1 
ATOM   2161 C  CG1 . ILE A 1 293 ? 32.33523  6.72794   -14.81421 1.000 18.89436  ?  293 ILE A CG1 1 
ATOM   2162 C  CG2 . ILE A 1 293 ? 32.21217  8.97633   -15.93317 1.000 18.24154  ?  293 ILE A CG2 1 
ATOM   2163 C  CD1 . ILE A 1 293 ? 32.95022  5.96991   -15.96870 1.000 18.66279  ?  293 ILE A CD1 1 
ATOM   2164 N  N   . LEU A 1 294 ? 29.98575  10.75004  -14.34718 1.000 25.19294  ?  294 LEU A N   1 
ATOM   2165 C  CA  . LEU A 1 294 ? 29.10353  11.84314  -14.74157 1.000 27.52388  ?  294 LEU A CA  1 
ATOM   2166 C  C   . LEU A 1 294 ? 29.29288  12.16102  -16.21979 1.000 26.88573  ?  294 LEU A C   1 
ATOM   2167 O  O   . LEU A 1 294 ? 30.41814  12.39520  -16.67127 1.000 25.11693  ?  294 LEU A O   1 
ATOM   2168 C  CB  . LEU A 1 294 ? 29.37017  13.09006  -13.89754 1.000 25.22513  ?  294 LEU A CB  1 
ATOM   2169 C  CG  . LEU A 1 294 ? 28.51712  14.31897  -14.21857 1.000 16.61546  ?  294 LEU A CG  1 
ATOM   2170 C  CD1 . LEU A 1 294 ? 27.04337  13.99695  -14.06535 1.000 17.69893  ?  294 LEU A CD1 1 
ATOM   2171 C  CD2 . LEU A 1 294 ? 28.90401  15.48855  -13.32965 1.000 17.92568  ?  294 LEU A CD2 1 
ATOM   2172 N  N   . SER A 1 295 ? 28.19154  12.17782  -16.96639 1.000 26.71145  ?  295 SER A N   1 
ATOM   2173 C  CA  . SER A 1 295 ? 28.21941  12.39984  -18.40588 1.000 26.74602  ?  295 SER A CA  1 
ATOM   2174 C  C   . SER A 1 295 ? 27.57946  13.73977  -18.74625 1.000 29.92421  ?  295 SER A C   1 
ATOM   2175 O  O   . SER A 1 295 ? 26.44174  14.01089  -18.34650 1.000 26.47835  ?  295 SER A O   1 
ATOM   2176 C  CB  . SER A 1 295 ? 27.50068  11.26941  -19.14777 1.000 19.01193  ?  295 SER A CB  1 
ATOM   2177 O  OG  . SER A 1 295 ? 26.12522  11.22526  -18.81048 1.000 23.17672  ?  295 SER A OG  1 
ATOM   2178 N  N   . GLY A 1 296 ? 28.31784  14.57238  -19.48265 1.000 24.58700  ?  296 GLY A N   1 
ATOM   2179 C  CA  . GLY A 1 296 ? 27.79802  15.79389  -20.05105 1.000 18.07385  ?  296 GLY A CA  1 
ATOM   2180 C  C   . GLY A 1 296 ? 27.65207  15.65610  -21.55903 1.000 14.98824  ?  296 GLY A C   1 
ATOM   2181 O  O   . GLY A 1 296 ? 28.09041  14.68378  -22.16526 1.000 16.44087  ?  296 GLY A O   1 
ATOM   2182 N  N   . LEU A 1 297 ? 27.02672  16.66012  -22.16191 1.000 14.06332  ?  297 LEU A N   1 
ATOM   2183 C  CA  . LEU A 1 297 ? 26.69390  16.60970  -23.57815 1.000 18.62621  ?  297 LEU A CA  1 
ATOM   2184 C  C   . LEU A 1 297 ? 27.66367  17.44961  -24.40305 1.000 17.13758  ?  297 LEU A C   1 
ATOM   2185 O  O   . LEU A 1 297 ? 28.14123  18.49801  -23.96253 1.000 16.31691  ?  297 LEU A O   1 
ATOM   2186 C  CB  . LEU A 1 297 ? 25.25422  17.07190  -23.80830 1.000 16.70671  ?  297 LEU A CB  1 
ATOM   2187 C  CG  . LEU A 1 297 ? 24.22125  16.09028  -23.24640 1.000 17.03796  ?  297 LEU A CG  1 
ATOM   2188 C  CD1 . LEU A 1 297 ? 22.82195  16.68130  -23.26483 1.000 24.06355  ?  297 LEU A CD1 1 
ATOM   2189 C  CD2 . LEU A 1 297 ? 24.26120  14.77496  -24.01504 1.000 14.10521  ?  297 LEU A CD2 1 
ATOM   2190 N  N   . ARG A 1 298 ? 27.94553  16.97054  -25.61543 1.000 21.29506  ?  298 ARG A N   1 
ATOM   2191 C  CA  . ARG A 1 298 ? 28.94383  17.56537  -26.49565 1.000 19.08324  ?  298 ARG A CA  1 
ATOM   2192 C  C   . ARG A 1 298 ? 28.46409  18.83014  -27.19180 1.000 18.62910  ?  298 ARG A C   1 
ATOM   2193 O  O   . ARG A 1 298 ? 29.22618  19.40835  -27.97219 1.000 20.09597  ?  298 ARG A O   1 
ATOM   2194 C  CB  . ARG A 1 298 ? 29.38744  16.55175  -27.55574 1.000 17.38664  ?  298 ARG A CB  1 
ATOM   2195 C  CG  . ARG A 1 298 ? 30.28269  15.45531  -27.02630 1.000 20.64055  ?  298 ARG A CG  1 
ATOM   2196 C  CD  . ARG A 1 298 ? 30.90202  14.64862  -28.15120 1.000 18.64652  ?  298 ARG A CD  1 
ATOM   2197 N  NE  . ARG A 1 298 ? 31.99592  13.82442  -27.65479 1.000 22.70959  ?  298 ARG A NE  1 
ATOM   2198 C  CZ  . ARG A 1 298 ? 33.22531  14.27122  -27.43997 1.000 19.65948  ?  298 ARG A CZ  1 
ATOM   2199 N  NH1 . ARG A 1 298 ? 33.55830  15.52628  -27.69287 1.000 13.92038  ?  298 ARG A NH1 1 
ATOM   2200 N  NH2 . ARG A 1 298 ? 34.14220  13.43994  -26.95499 1.000 24.34893  ?  298 ARG A NH2 1 
ATOM   2201 N  N   . PHE A 1 299 ? 27.23218  19.26941  -26.95053 1.000 18.29742  ?  299 PHE A N   1 
ATOM   2202 C  CA  . PHE A 1 299 ? 26.71574  20.47058  -27.58679 1.000 18.90166  ?  299 PHE A CA  1 
ATOM   2203 C  C   . PHE A 1 299 ? 26.34837  21.56621  -26.59644 1.000 23.00722  ?  299 PHE A C   1 
ATOM   2204 O  O   . PHE A 1 299 ? 25.86015  22.62088  -27.01876 1.000 26.71873  ?  299 PHE A O   1 
ATOM   2205 C  CB  . PHE A 1 299 ? 25.49873  20.13015  -28.45915 1.000 19.01467  ?  299 PHE A CB  1 
ATOM   2206 C  CG  . PHE A 1 299 ? 24.38514  19.45178  -27.71365 1.000 29.44680  ?  299 PHE A CG  1 
ATOM   2207 C  CD1 . PHE A 1 299 ? 24.35996  18.07282  -27.58243 1.000 26.02412  ?  299 PHE A CD1 1 
ATOM   2208 C  CD2 . PHE A 1 299 ? 23.35762  20.19264  -27.15137 1.000 36.04589  ?  299 PHE A CD2 1 
ATOM   2209 C  CE1 . PHE A 1 299 ? 23.33495  17.44644  -26.89909 1.000 26.61903  ?  299 PHE A CE1 1 
ATOM   2210 C  CE2 . PHE A 1 299 ? 22.33053  19.57247  -26.46718 1.000 32.73799  ?  299 PHE A CE2 1 
ATOM   2211 C  CZ  . PHE A 1 299 ? 22.31808  18.19790  -26.34285 1.000 30.45347  ?  299 PHE A CZ  1 
ATOM   2212 N  N   . LYS A 1 300 ? 26.56957  21.35560  -25.30167 1.000 20.57932  ?  300 LYS A N   1 
ATOM   2213 C  CA  . LYS A 1 300 ? 26.28848  22.38788  -24.31794 1.000 19.62023  ?  300 LYS A CA  1 
ATOM   2214 C  C   . LYS A 1 300 ? 27.32942  23.50210  -24.39698 1.000 24.96898  ?  300 LYS A C   1 
ATOM   2215 O  O   . LYS A 1 300 ? 28.41247  23.34366  -24.96704 1.000 22.35495  ?  300 LYS A O   1 
ATOM   2216 C  CB  . LYS A 1 300 ? 26.26593  21.79980  -22.90639 1.000 17.98695  ?  300 LYS A CB  1 
ATOM   2217 C  CG  . LYS A 1 300 ? 25.21211  20.73009  -22.67855 1.000 15.03030  ?  300 LYS A CG  1 
ATOM   2218 C  CD  . LYS A 1 300 ? 23.82324  21.24963  -22.99253 1.000 19.09709  ?  300 LYS A CD  1 
ATOM   2219 C  CE  . LYS A 1 300 ? 22.74812  20.34231  -22.42061 1.000 28.21654  ?  300 LYS A CE  1 
ATOM   2220 N  NZ  . LYS A 1 300 ? 22.78432  20.32618  -20.93239 1.000 23.97774  ?  300 LYS A NZ  1 
ATOM   2221 N  N   . SER A 1 301 ? 26.98404  24.64569  -23.81357 1.000 25.23587  ?  301 SER A N   1 
ATOM   2222 C  CA  . SER A 1 301 ? 27.91216  25.76386  -23.75744 1.000 23.15985  ?  301 SER A CA  1 
ATOM   2223 C  C   . SER A 1 301 ? 29.10023  25.42602  -22.86325 1.000 25.88675  ?  301 SER A C   1 
ATOM   2224 O  O   . SER A 1 301 ? 28.99744  24.62188  -21.93281 1.000 23.24626  ?  301 SER A O   1 
ATOM   2225 C  CB  . SER A 1 301 ? 27.20522  27.01694  -23.24268 1.000 22.16856  ?  301 SER A CB  1 
ATOM   2226 O  OG  . SER A 1 301 ? 26.57367  26.76536  -21.99958 1.000 29.04343  ?  301 SER A OG  1 
ATOM   2227 N  N   . GLN A 1 302 ? 30.24466  26.04725  -23.16524 1.000 27.24999  ?  302 GLN A N   1 
ATOM   2228 C  CA  . GLN A 1 302 ? 31.44013  25.84359  -22.35208 1.000 18.33991  ?  302 GLN A CA  1 
ATOM   2229 C  C   . GLN A 1 302 ? 31.20785  26.25358  -20.90456 1.000 19.58232  ?  302 GLN A C   1 
ATOM   2230 O  O   . GLN A 1 302 ? 31.80794  25.67779  -19.99108 1.000 14.01193  ?  302 GLN A O   1 
ATOM   2231 C  CB  . GLN A 1 302 ? 32.60916  26.62901  -22.94134 1.000 12.40263  ?  302 GLN A CB  1 
ATOM   2232 C  CG  . GLN A 1 302 ? 32.81780  26.39793  -24.42310 1.000 17.39696  ?  302 GLN A CG  1 
ATOM   2233 C  CD  . GLN A 1 302 ? 33.48611  27.57460  -25.10226 1.000 34.13900  ?  302 GLN A CD  1 
ATOM   2234 O  OE1 . GLN A 1 302 ? 32.84959  28.59514  -25.36731 1.000 53.32409  ?  302 GLN A OE1 1 
ATOM   2235 N  NE2 . GLN A 1 302 ? 34.77727  27.44175  -25.38401 1.000 29.93376  ?  302 GLN A NE2 1 
ATOM   2236 N  N   . GLU A 1 303 ? 30.34495  27.24530  -20.68016 1.000 29.20701  ?  303 GLU A N   1 
ATOM   2237 C  CA  . GLU A 1 303 ? 29.98546  27.64319  -19.32299 1.000 32.45734  ?  303 GLU A CA  1 
ATOM   2238 C  C   . GLU A 1 303 ? 29.29007  26.50337  -18.58333 1.000 31.27441  ?  303 GLU A C   1 
ATOM   2239 O  O   . GLU A 1 303 ? 29.65236  26.16482  -17.44809 1.000 33.45845  ?  303 GLU A O   1 
ATOM   2240 C  CB  . GLU A 1 303 ? 29.09468  28.88549  -19.38978 1.000 41.51617  ?  303 GLU A CB  1 
ATOM   2241 C  CG  . GLU A 1 303 ? 28.69144  29.48843  -18.06018 1.000 53.66281  ?  303 GLU A CG  1 
ATOM   2242 C  CD  . GLU A 1 303 ? 27.89193  30.76852  -18.23864 1.000 56.31014  ?  303 GLU A CD  1 
ATOM   2243 O  OE1 . GLU A 1 303 ? 27.92239  31.33928  -19.35065 1.000 44.84512  ?  303 GLU A OE1 1 
ATOM   2244 O  OE2 . GLU A 1 303 ? 27.23004  31.20184  -17.27268 1.000 56.31648  -1 303 GLU A OE2 1 
ATOM   2245 N  N   . GLU A 1 304 ? 28.29499  25.88537  -19.22570 1.000 26.51668  ?  304 GLU A N   1 
ATOM   2246 C  CA  . GLU A 1 304 ? 27.58178  24.77272  -18.60548 1.000 27.01516  ?  304 GLU A CA  1 
ATOM   2247 C  C   . GLU A 1 304 ? 28.49970  23.57534  -18.38858 1.000 27.08580  ?  304 GLU A C   1 
ATOM   2248 O  O   . GLU A 1 304 ? 28.42378  22.90213  -17.35277 1.000 29.01253  ?  304 GLU A O   1 
ATOM   2249 C  CB  . GLU A 1 304 ? 26.37609  24.38555  -19.46461 1.000 26.63565  ?  304 GLU A CB  1 
ATOM   2250 C  CG  . GLU A 1 304 ? 25.79674  23.00275  -19.17603 1.000 42.41281  ?  304 GLU A CG  1 
ATOM   2251 C  CD  . GLU A 1 304 ? 25.04710  22.92285  -17.85526 1.000 42.07449  ?  304 GLU A CD  1 
ATOM   2252 O  OE1 . GLU A 1 304 ? 24.94137  23.95044  -17.15273 1.000 52.08521  ?  304 GLU A OE1 1 
ATOM   2253 O  OE2 . GLU A 1 304 ? 24.55601  21.82396  -17.52130 1.000 36.64261  -1 304 GLU A OE2 1 
ATOM   2254 N  N   . ILE A 1 305 ? 29.37249  23.29102  -19.35631 1.000 28.62988  ?  305 ILE A N   1 
ATOM   2255 C  CA  . ILE A 1 305 ? 30.29315  22.16835  -19.21283 1.000 22.80894  ?  305 ILE A CA  1 
ATOM   2256 C  C   . ILE A 1 305 ? 31.27734  22.42414  -18.07677 1.000 21.25706  ?  305 ILE A C   1 
ATOM   2257 O  O   . ILE A 1 305 ? 31.63016  21.50660  -17.32915 1.000 21.18998  ?  305 ILE A O   1 
ATOM   2258 C  CB  . ILE A 1 305 ? 31.00710  21.89175  -20.54833 1.000 15.79167  ?  305 ILE A CB  1 
ATOM   2259 C  CG1 . ILE A 1 305 ? 29.98458  21.48978  -21.61188 1.000 13.91286  ?  305 ILE A CG1 1 
ATOM   2260 C  CG2 . ILE A 1 305 ? 32.05031  20.79878  -20.38712 1.000 17.03145  ?  305 ILE A CG2 1 
ATOM   2261 C  CD1 . ILE A 1 305 ? 29.14911  20.28690  -21.22828 1.000 14.56452  ?  305 ILE A CD1 1 
ATOM   2262 N  N   . LEU A 1 306 ? 31.72958  23.67124  -17.91984 1.000 19.78503  ?  306 LEU A N   1 
ATOM   2263 C  CA  . LEU A 1 306 ? 32.58190  24.00899  -16.78291 1.000 19.88129  ?  306 LEU A CA  1 
ATOM   2264 C  C   . LEU A 1 306 ? 31.83838  23.82866  -15.46597 1.000 21.07881  ?  306 LEU A C   1 
ATOM   2265 O  O   . LEU A 1 306 ? 32.40889  23.34324  -14.47958 1.000 20.58103  ?  306 LEU A O   1 
ATOM   2266 C  CB  . LEU A 1 306 ? 33.09369  25.44280  -16.91633 1.000 21.25737  ?  306 LEU A CB  1 
ATOM   2267 C  CG  . LEU A 1 306 ? 33.84496  26.00462  -15.70669 1.000 17.14146  ?  306 LEU A CG  1 
ATOM   2268 C  CD1 . LEU A 1 306 ? 35.10484  25.19732  -15.42823 1.000 19.99004  ?  306 LEU A CD1 1 
ATOM   2269 C  CD2 . LEU A 1 306 ? 34.17786  27.47289  -15.91289 1.000 11.91249  ?  306 LEU A CD2 1 
ATOM   2270 N  N   . ASN A 1 307 ? 30.56487  24.22675  -15.42874 1.000 20.91763  ?  307 ASN A N   1 
ATOM   2271 C  CA  . ASN A 1 307 ? 29.75868  23.99792  -14.23408 1.000 20.34890  ?  307 ASN A CA  1 
ATOM   2272 C  C   . ASN A 1 307 ? 29.68589  22.51087  -13.90865 1.000 19.38443  ?  307 ASN A C   1 
ATOM   2273 O  O   . ASN A 1 307 ? 29.81916  22.10756  -12.74526 1.000 19.96408  ?  307 ASN A O   1 
ATOM   2274 C  CB  . ASN A 1 307 ? 28.35690  24.57445  -14.43528 1.000 24.10333  ?  307 ASN A CB  1 
ATOM   2275 C  CG  . ASN A 1 307 ? 27.83827  25.29398  -13.20709 1.000 34.80241  ?  307 ASN A CG  1 
ATOM   2276 O  OD1 . ASN A 1 307 ? 27.37577  24.66714  -12.25325 1.000 37.02350  ?  307 ASN A OD1 1 
ATOM   2277 N  ND2 . ASN A 1 307 ? 27.90429  26.62077  -13.22843 1.000 29.62953  ?  307 ASN A ND2 1 
ATOM   2278 N  N   . GLU A 1 308 ? 29.49330  21.67991  -14.93364 1.000 21.83933  ?  308 GLU A N   1 
ATOM   2279 C  CA  . GLU A 1 308 ? 29.43055  20.23727  -14.72116 1.000 22.19374  ?  308 GLU A CA  1 
ATOM   2280 C  C   . GLU A 1 308 ? 30.77454  19.68044  -14.26515 1.000 21.09904  ?  308 GLU A C   1 
ATOM   2281 O  O   . GLU A 1 308 ? 30.82054  18.74589  -13.45999 1.000 22.18248  ?  308 GLU A O   1 
ATOM   2282 C  CB  . GLU A 1 308 ? 28.96189  19.53988  -15.99608 1.000 19.01063  ?  308 GLU A CB  1 
ATOM   2283 C  CG  . GLU A 1 308 ? 27.55682  19.92467  -16.41872 1.000 17.39403  ?  308 GLU A CG  1 
ATOM   2284 C  CD  . GLU A 1 308 ? 27.11367  19.20053  -17.66700 1.000 18.29185  ?  308 GLU A CD  1 
ATOM   2285 O  OE1 . GLU A 1 308 ? 27.80800  18.24655  -18.07143 1.000 23.62463  ?  308 GLU A OE1 1 
ATOM   2286 O  OE2 . GLU A 1 308 ? 26.07597  19.58517  -18.24478 1.000 18.23234  -1 308 GLU A OE2 1 
ATOM   2287 N  N   . VAL A 1 309 ? 31.87809  20.23408  -14.77180 1.000 18.16311  ?  309 VAL A N   1 
ATOM   2288 C  CA  . VAL A 1 309 ? 33.19998  19.79176  -14.33063 1.000 16.04997  ?  309 VAL A CA  1 
ATOM   2289 C  C   . VAL A 1 309 ? 33.40708  20.12510  -12.85833 1.000 16.33192  ?  309 VAL A C   1 
ATOM   2290 O  O   . VAL A 1 309 ? 33.95911  19.32339  -12.09478 1.000 20.57417  ?  309 VAL A O   1 
ATOM   2291 C  CB  . VAL A 1 309 ? 34.30101  20.40876  -15.21432 1.000 15.61476  ?  309 VAL A CB  1 
ATOM   2292 C  CG1 . VAL A 1 309 ? 35.67624  20.11753  -14.63261 1.000 15.00391  ?  309 VAL A CG1 1 
ATOM   2293 C  CG2 . VAL A 1 309 ? 34.20951  19.86785  -16.63094 1.000 19.79791  ?  309 VAL A CG2 1 
ATOM   2294 N  N   . LYS A 1 310 ? 32.97397  21.31515  -12.43725 1.000 18.07893  ?  310 LYS A N   1 
ATOM   2295 C  CA  . LYS A 1 310 ? 33.06794  21.67311  -11.02335 1.000 19.39238  ?  310 LYS A CA  1 
ATOM   2296 C  C   . LYS A 1 310 ? 32.20763  20.75186  -10.16334 1.000 21.92336  ?  310 LYS A C   1 
ATOM   2297 O  O   . LYS A 1 310 ? 32.62656  20.32681  -9.07595  1.000 26.38658  ?  310 LYS A O   1 
ATOM   2298 C  CB  . LYS A 1 310 ? 32.66735  23.13559  -10.82380 1.000 17.83599  ?  310 LYS A CB  1 
ATOM   2299 C  CG  . LYS A 1 310 ? 33.60085  24.12568  -11.50660 1.000 20.49533  ?  310 LYS A CG  1 
ATOM   2300 C  CD  . LYS A 1 310 ? 33.17071  25.56569  -11.27395 1.000 19.86628  ?  310 LYS A CD  1 
ATOM   2301 C  CE  . LYS A 1 310 ? 34.12205  26.53704  -11.95914 1.000 20.15200  ?  310 LYS A CE  1 
ATOM   2302 N  NZ  . LYS A 1 310 ? 33.73562  27.95797  -11.73852 1.000 14.49870  ?  310 LYS A NZ  1 
ATOM   2303 N  N   . ILE A 1 311 ? 31.00106  20.42968  -10.63809 1.000 17.15882  ?  311 ILE A N   1 
ATOM   2304 C  CA  . ILE A 1 311 ? 30.14540  19.48650  -9.92056  1.000 18.25834  ?  311 ILE A CA  1 
ATOM   2305 C  C   . ILE A 1 311 ? 30.82750  18.12784  -9.80972  1.000 21.72374  ?  311 ILE A C   1 
ATOM   2306 O  O   . ILE A 1 311 ? 30.77083  17.46817  -8.76364  1.000 22.74674  ?  311 ILE A O   1 
ATOM   2307 C  CB  . ILE A 1 311 ? 28.77391  19.37618  -10.61237 1.000 15.27428  ?  311 ILE A CB  1 
ATOM   2308 C  CG1 . ILE A 1 311 ? 28.02877  20.71008  -10.54379 1.000 15.13046  ?  311 ILE A CG1 1 
ATOM   2309 C  CG2 . ILE A 1 311 ? 27.94211  18.26683  -9.98424  1.000 15.46246  ?  311 ILE A CG2 1 
ATOM   2310 C  CD1 . ILE A 1 311 ? 26.71280  20.71138  -11.29289 1.000 11.16391  ?  311 ILE A CD1 1 
ATOM   2311 N  N   . ALA A 1 312 ? 31.47691  17.68768  -10.88980 1.000 19.35332  ?  312 ALA A N   1 
ATOM   2312 C  CA  . ALA A 1 312 ? 32.18045  16.41041  -10.87476 1.000 17.28739  ?  312 ALA A CA  1 
ATOM   2313 C  C   . ALA A 1 312 ? 33.33635  16.42865  -9.88462  1.000 21.53279  ?  312 ALA A C   1 
ATOM   2314 O  O   . ALA A 1 312 ? 33.58240  15.43656  -9.19192  1.000 26.27027  ?  312 ALA A O   1 
ATOM   2315 C  CB  . ALA A 1 312 ? 32.67982  16.07074  -12.27847 1.000 14.99556  ?  312 ALA A CB  1 
ATOM   2316 N  N   . MET A 1 313 ? 34.06353  17.54520  -9.81098  1.000 21.24619  ?  313 MET A N   1 
ATOM   2317 C  CA  . MET A 1 313 ? 35.13598  17.66583  -8.82655  1.000 23.36824  ?  313 MET A CA  1 
ATOM   2318 C  C   . MET A 1 313 ? 34.58733  17.55382  -7.40972  1.000 26.61368  ?  313 MET A C   1 
ATOM   2319 O  O   . MET A 1 313 ? 35.13761  16.82875  -6.56930  1.000 24.50270  ?  313 MET A O   1 
ATOM   2320 C  CB  . MET A 1 313 ? 35.87391  18.99273  -9.00806  1.000 20.23200  ?  313 MET A CB  1 
ATOM   2321 C  CG  . MET A 1 313 ? 36.62262  19.12612  -10.31952 1.000 21.91642  ?  313 MET A CG  1 
ATOM   2322 S  SD  . MET A 1 313 ? 37.38173  20.75154  -10.50334 1.000 30.31709  ?  313 MET A SD  1 
ATOM   2323 C  CE  . MET A 1 313 ? 38.53009  20.74993  -9.12963  1.000 25.77642  ?  313 MET A CE  1 
ATOM   2324 N  N   . ASP A 1 314 ? 33.48726  18.25982  -7.13227  1.000 30.26461  ?  314 ASP A N   1 
ATOM   2325 C  CA  . ASP A 1 314 ? 32.89082  18.19760  -5.80038  1.000 32.32771  ?  314 ASP A CA  1 
ATOM   2326 C  C   . ASP A 1 314 ? 32.43670  16.78257  -5.46225  1.000 30.42579  ?  314 ASP A C   1 
ATOM   2327 O  O   . ASP A 1 314 ? 32.66670  16.29768  -4.34725  1.000 26.14956  ?  314 ASP A O   1 
ATOM   2328 C  CB  . ASP A 1 314 ? 31.71840  19.17335  -5.69867  1.000 30.32010  ?  314 ASP A CB  1 
ATOM   2329 C  CG  . ASP A 1 314 ? 32.16862  20.61470  -5.57318  1.000 48.05546  ?  314 ASP A CG  1 
ATOM   2330 O  OD1 . ASP A 1 314 ? 33.39189  20.85211  -5.48179  1.000 51.31206  ?  314 ASP A OD1 1 
ATOM   2331 O  OD2 . ASP A 1 314 ? 31.29785  21.51042  -5.56450  1.000 58.39698  -1 314 ASP A OD2 1 
ATOM   2332 N  N   . LEU A 1 315 ? 31.79840  16.10032  -6.41650  1.000 24.98326  ?  315 LEU A N   1 
ATOM   2333 C  CA  . LEU A 1 315 ? 31.29494  14.75659  -6.15099  1.000 24.17159  ?  315 LEU A CA  1 
ATOM   2334 C  C   . LEU A 1 315 ? 32.42232  13.73890  -6.02992  1.000 23.67220  ?  315 LEU A C   1 
ATOM   2335 O  O   . LEU A 1 315 ? 32.28991  12.75885  -5.28866  1.000 23.02667  ?  315 LEU A O   1 
ATOM   2336 C  CB  . LEU A 1 315 ? 30.31065  14.33710  -7.24148  1.000 23.76219  ?  315 LEU A CB  1 
ATOM   2337 C  CG  . LEU A 1 315 ? 28.98072  15.09212  -7.24457  1.000 22.86193  ?  315 LEU A CG  1 
ATOM   2338 C  CD1 . LEU A 1 315 ? 28.01391  14.47530  -8.24205  1.000 24.74456  ?  315 LEU A CD1 1 
ATOM   2339 C  CD2 . LEU A 1 315 ? 28.37614  15.11699  -5.84855  1.000 19.91944  ?  315 LEU A CD2 1 
ATOM   2340 N  N   . HIS A 1 316 ? 33.52745  13.93993  -6.75109  1.000 23.59500  ?  316 HIS A N   1 
ATOM   2341 C  CA  . HIS A 1 316 ? 34.67344  13.05283  -6.59743  1.000 24.37098  ?  316 HIS A CA  1 
ATOM   2342 C  C   . HIS A 1 316 ? 35.36382  13.27195  -5.25923  1.000 25.93289  ?  316 HIS A C   1 
ATOM   2343 O  O   . HIS A 1 316 ? 35.90425  12.32283  -4.68016  1.000 26.36150  ?  316 HIS A O   1 
ATOM   2344 C  CB  . HIS A 1 316 ? 35.65685  13.25424  -7.75150  1.000 24.32789  ?  316 HIS A CB  1 
ATOM   2345 C  CG  . HIS A 1 316 ? 36.73738  12.21942  -7.81239  1.000 21.08429  ?  316 HIS A CG  1 
ATOM   2346 N  ND1 . HIS A 1 316 ? 36.47095  10.86879  -7.87491  1.000 21.34398  ?  316 HIS A ND1 1 
ATOM   2347 C  CD2 . HIS A 1 316 ? 38.08637  12.33699  -7.82268  1.000 27.09267  ?  316 HIS A CD2 1 
ATOM   2348 C  CE1 . HIS A 1 316 ? 37.60873  10.19879  -7.91916  1.000 24.70080  ?  316 HIS A CE1 1 
ATOM   2349 N  NE2 . HIS A 1 316 ? 38.60418  11.06621  -7.88879  1.000 23.76231  ?  316 HIS A NE2 1 
ATOM   2350 N  N   . LYS A 1 317 ? 35.36501  14.50970  -4.75711  1.000 24.95122  ?  317 LYS A N   1 
ATOM   2351 C  CA  . LYS A 1 317 ? 35.87101  14.74905  -3.40878  1.000 22.10448  ?  317 LYS A CA  1 
ATOM   2352 C  C   . LYS A 1 317 ? 34.97621  14.09304  -2.36292  1.000 19.67043  ?  317 LYS A C   1 
ATOM   2353 O  O   . LYS A 1 317 ? 35.45606  13.35815  -1.49132  1.000 12.06597  ?  317 LYS A O   1 
ATOM   2354 C  CB  . LYS A 1 317 ? 35.98277  16.25034  -3.14050  1.000 31.38835  ?  317 LYS A CB  1 
ATOM   2355 C  CG  . LYS A 1 317 ? 36.98425  16.98536  -4.00970  1.000 36.45907  ?  317 LYS A CG  1 
ATOM   2356 C  CD  . LYS A 1 317 ? 36.88869  18.48555  -3.77998  1.000 29.58794  ?  317 LYS A CD  1 
ATOM   2357 C  CE  . LYS A 1 317 ? 37.49308  19.26584  -4.93438  1.000 26.11719  ?  317 LYS A CE  1 
ATOM   2358 N  NZ  . LYS A 1 317 ? 37.18167  20.71813  -4.83404  1.000 31.30981  ?  317 LYS A NZ  1 
ATOM   2359 N  N   . LYS A 1 318 ? 33.66531  14.33810  -2.44399  1.000 22.19850  ?  318 LYS A N   1 
ATOM   2360 C  CA  . LYS A 1 318 ? 32.75383  13.91442  -1.38565  1.000 21.24147  ?  318 LYS A CA  1 
ATOM   2361 C  C   . LYS A 1 318 ? 32.46408  12.41902  -1.42409  1.000 22.08207  ?  318 LYS A C   1 
ATOM   2362 O  O   . LYS A 1 318 ? 32.20500  11.81808  -0.37559  1.000 26.93474  ?  318 LYS A O   1 
ATOM   2363 C  CB  . LYS A 1 318 ? 31.44726  14.70540  -1.47403  1.000 17.34892  ?  318 LYS A CB  1 
ATOM   2364 C  CG  . LYS A 1 318 ? 30.52541  14.52185  -0.27845  1.000 18.28958  ?  318 LYS A CG  1 
ATOM   2365 C  CD  . LYS A 1 318 ? 29.36975  15.50978  -0.31142  1.000 22.44801  ?  318 LYS A CD  1 
ATOM   2366 C  CE  . LYS A 1 318 ? 28.46046  15.33504  0.89497   1.000 24.85027  ?  318 LYS A CE  1 
ATOM   2367 N  NZ  . LYS A 1 318 ? 27.39739  16.37655  0.94800   1.000 27.97606  ?  318 LYS A NZ  1 
ATOM   2368 N  N   . TYR A 1 319 ? 32.50504  11.80275  -2.60252  1.000 25.11492  ?  319 TYR A N   1 
ATOM   2369 C  CA  . TYR A 1 319 ? 32.22642  10.37584  -2.76639  1.000 24.69941  ?  319 TYR A CA  1 
ATOM   2370 C  C   . TYR A 1 319 ? 33.36336  9.74384   -3.55960  1.000 25.74808  ?  319 TYR A C   1 
ATOM   2371 O  O   . TYR A 1 319 ? 33.17509  9.30166   -4.69942  1.000 31.09104  ?  319 TYR A O   1 
ATOM   2372 C  CB  . TYR A 1 319 ? 30.88138  10.15607  -3.46140  1.000 24.78122  ?  319 TYR A CB  1 
ATOM   2373 C  CG  . TYR A 1 319 ? 29.73576  10.94852  -2.86610  1.000 24.53146  ?  319 TYR A CG  1 
ATOM   2374 C  CD1 . TYR A 1 319 ? 29.48137  12.25228  -3.27414  1.000 21.63215  ?  319 TYR A CD1 1 
ATOM   2375 C  CD2 . TYR A 1 319 ? 28.90466  10.39074  -1.90235  1.000 24.47097  ?  319 TYR A CD2 1 
ATOM   2376 C  CE1 . TYR A 1 319 ? 28.43614  12.97884  -2.73654  1.000 27.52710  ?  319 TYR A CE1 1 
ATOM   2377 C  CE2 . TYR A 1 319 ? 27.85603  11.11087  -1.35805  1.000 18.42810  ?  319 TYR A CE2 1 
ATOM   2378 C  CZ  . TYR A 1 319 ? 27.62687  12.40385  -1.77898  1.000 22.46715  ?  319 TYR A CZ  1 
ATOM   2379 O  OH  . TYR A 1 319 ? 26.58569  13.12529  -1.24141  1.000 18.75949  ?  319 TYR A OH  1 
ATOM   2380 N  N   . PRO A 1 320 ? 34.56535  9.67902   -2.97701  1.000 21.62515  ?  320 PRO A N   1 
ATOM   2381 C  CA  . PRO A 1 320 ? 35.72766  9.20561   -3.74613  1.000 21.13357  ?  320 PRO A CA  1 
ATOM   2382 C  C   . PRO A 1 320 ? 35.63728  7.75252   -4.17680  1.000 23.37006  ?  320 PRO A C   1 
ATOM   2383 O  O   . PRO A 1 320 ? 36.33078  7.36659   -5.12619  1.000 25.18961  ?  320 PRO A O   1 
ATOM   2384 C  CB  . PRO A 1 320 ? 36.89891  9.42739   -2.78065  1.000 23.71247  ?  320 PRO A CB  1 
ATOM   2385 C  CG  . PRO A 1 320 ? 36.27983  9.35258   -1.42802  1.000 21.63632  ?  320 PRO A CG  1 
ATOM   2386 C  CD  . PRO A 1 320 ? 34.90732  9.94933   -1.56925  1.000 21.62779  ?  320 PRO A CD  1 
ATOM   2387 N  N   . ASP A 1 321 ? 34.81535  6.93584   -3.51934  1.000 22.97939  ?  321 ASP A N   1 
ATOM   2388 C  CA  . ASP A 1 321 ? 34.74547  5.51849   -3.84968  1.000 25.93500  ?  321 ASP A CA  1 
ATOM   2389 C  C   . ASP A 1 321 ? 33.64896  5.19335   -4.85386  1.000 27.02770  ?  321 ASP A C   1 
ATOM   2390 O  O   . ASP A 1 321 ? 33.77113  4.21021   -5.59454  1.000 28.00012  ?  321 ASP A O   1 
ATOM   2391 C  CB  . ASP A 1 321 ? 34.53143  4.69084   -2.57994  1.000 25.76994  ?  321 ASP A CB  1 
ATOM   2392 C  CG  . ASP A 1 321 ? 34.61831  3.20024   -2.83783  1.000 42.85894  ?  321 ASP A CG  1 
ATOM   2393 O  OD1 . ASP A 1 321 ? 35.74006  2.70407   -3.07629  1.000 47.25168  ?  321 ASP A OD1 1 
ATOM   2394 O  OD2 . ASP A 1 321 ? 33.56618  2.52642   -2.80898  1.000 36.94663  -1 321 ASP A OD2 1 
ATOM   2395 N  N   . PHE A 1 322 ? 32.58617  5.99387   -4.90348  1.000 20.70468  ?  322 PHE A N   1 
ATOM   2396 C  CA  . PHE A 1 322 ? 31.44434  5.71658   -5.76636  1.000 18.95359  ?  322 PHE A CA  1 
ATOM   2397 C  C   . PHE A 1 322 ? 31.43004  6.56807   -7.02837  1.000 23.02433  ?  322 PHE A C   1 
ATOM   2398 O  O   . PHE A 1 322 ? 31.00810  6.09068   -8.08607  1.000 20.32991  ?  322 PHE A O   1 
ATOM   2399 C  CB  . PHE A 1 322 ? 30.14138  5.92572   -4.98856  1.000 22.84414  ?  322 PHE A CB  1 
ATOM   2400 C  CG  . PHE A 1 322 ? 28.92631  5.37694   -5.67733  1.000 18.45095  ?  322 PHE A CG  1 
ATOM   2401 C  CD1 . PHE A 1 322 ? 28.82081  4.02385   -5.95054  1.000 16.93287  ?  322 PHE A CD1 1 
ATOM   2402 C  CD2 . PHE A 1 322 ? 27.88099  6.21064   -6.03391  1.000 19.65224  ?  322 PHE A CD2 1 
ATOM   2403 C  CE1 . PHE A 1 322 ? 27.70013  3.51444   -6.57861  1.000 17.33116  ?  322 PHE A CE1 1 
ATOM   2404 C  CE2 . PHE A 1 322 ? 26.75827  5.70786   -6.66127  1.000 21.95264  ?  322 PHE A CE2 1 
ATOM   2405 C  CZ  . PHE A 1 322 ? 26.66783  4.35683   -6.93354  1.000 19.86055  ?  322 PHE A CZ  1 
ATOM   2406 N  N   . PHE A 1 323 ? 31.88402  7.81566   -6.94392  1.000 25.62101  ?  323 PHE A N   1 
ATOM   2407 C  CA  . PHE A 1 323 ? 31.96121  8.69659   -8.10101  1.000 21.82182  ?  323 PHE A CA  1 
ATOM   2408 C  C   . PHE A 1 323 ? 33.35419  8.59997   -8.71056  1.000 20.92975  ?  323 PHE A C   1 
ATOM   2409 O  O   . PHE A 1 323 ? 34.35614  8.80326   -8.01755  1.000 18.36866  ?  323 PHE A O   1 
ATOM   2410 C  CB  . PHE A 1 323 ? 31.64666  10.13730  -7.69796  1.000 16.17279  ?  323 PHE A CB  1 
ATOM   2411 C  CG  . PHE A 1 323 ? 31.50089  11.07691  -8.85850  1.000 21.57739  ?  323 PHE A CG  1 
ATOM   2412 C  CD1 . PHE A 1 323 ? 32.60517  11.72810  -9.38411  1.000 28.29515  ?  323 PHE A CD1 1 
ATOM   2413 C  CD2 . PHE A 1 323 ? 30.25685  11.31989  -9.41757  1.000 28.82429  ?  323 PHE A CD2 1 
ATOM   2414 C  CE1 . PHE A 1 323 ? 32.47346  12.59760  -10.45044 1.000 30.97106  ?  323 PHE A CE1 1 
ATOM   2415 C  CE2 . PHE A 1 323 ? 30.11818  12.19059  -10.48398 1.000 30.49357  ?  323 PHE A CE2 1 
ATOM   2416 C  CZ  . PHE A 1 323 ? 31.22868  12.83031  -10.99930 1.000 26.90203  ?  323 PHE A CZ  1 
ATOM   2417 N  N   . LEU A 1 324 ? 33.41493  8.29099   -10.00619 1.000 25.68734  ?  324 LEU A N   1 
ATOM   2418 C  CA  . LEU A 1 324 ? 34.69005  8.04548   -10.67258 1.000 22.32660  ?  324 LEU A CA  1 
ATOM   2419 C  C   . LEU A 1 324 ? 35.24539  9.30767   -11.32571 1.000 20.12646  ?  324 LEU A C   1 
ATOM   2420 O  O   . LEU A 1 324 ? 36.36823  9.72446   -11.02706 1.000 25.15502  ?  324 LEU A O   1 
ATOM   2421 C  CB  . LEU A 1 324 ? 34.52779  6.92869   -11.70803 1.000 19.71518  ?  324 LEU A CB  1 
ATOM   2422 C  CG  . LEU A 1 324 ? 34.05168  5.59782   -11.12739 1.000 19.46884  ?  324 LEU A CG  1 
ATOM   2423 C  CD1 . LEU A 1 324 ? 33.96252  4.53993   -12.21183 1.000 18.76613  ?  324 LEU A CD1 1 
ATOM   2424 C  CD2 . LEU A 1 324 ? 34.97507  5.15382   -10.00612 1.000 14.18215  ?  324 LEU A CD2 1 
ATOM   2425 N  N   . GLY A 1 325 ? 34.47483  9.92189   -12.21855 1.000 22.67561  ?  325 GLY A N   1 
ATOM   2426 C  CA  . GLY A 1 325 ? 34.95046  11.10296  -12.90997 1.000 25.77680  ?  325 GLY A CA  1 
ATOM   2427 C  C   . GLY A 1 325 ? 33.93595  11.73991  -13.83606 1.000 26.37404  ?  325 GLY A C   1 
ATOM   2428 O  O   . GLY A 1 325 ? 32.73752  11.76847  -13.53975 1.000 22.24188  ?  325 GLY A O   1 
ATOM   2429 N  N   . TYR A 1 326 ? 34.41026  12.24999  -14.96975 1.000 24.28066  ?  326 TYR A N   1 
ATOM   2430 C  CA  . TYR A 1 326 ? 33.58368  13.00034  -15.90080 1.000 24.00587  ?  326 TYR A CA  1 
ATOM   2431 C  C   . TYR A 1 326 ? 33.82118  12.50005  -17.31892 1.000 26.53513  ?  326 TYR A C   1 
ATOM   2432 O  O   . TYR A 1 326 ? 34.89401  11.98259  -17.64249 1.000 26.32057  ?  326 TYR A O   1 
ATOM   2433 C  CB  . TYR A 1 326 ? 33.88168  14.50577  -15.80334 1.000 24.11436  ?  326 TYR A CB  1 
ATOM   2434 C  CG  . TYR A 1 326 ? 32.97515  15.38529  -16.63242 1.000 21.12639  ?  326 TYR A CG  1 
ATOM   2435 C  CD1 . TYR A 1 326 ? 31.64985  15.58807  -16.27041 1.000 20.07376  ?  326 TYR A CD1 1 
ATOM   2436 C  CD2 . TYR A 1 326 ? 33.45033  16.02738  -17.76802 1.000 21.46551  ?  326 TYR A CD2 1 
ATOM   2437 C  CE1 . TYR A 1 326 ? 30.81939  16.39628  -17.02411 1.000 22.70672  ?  326 TYR A CE1 1 
ATOM   2438 C  CE2 . TYR A 1 326 ? 32.62897  16.83763  -18.52704 1.000 23.72924  ?  326 TYR A CE2 1 
ATOM   2439 C  CZ  . TYR A 1 326 ? 31.31496  17.01879  -18.15104 1.000 25.65148  ?  326 TYR A CZ  1 
ATOM   2440 O  OH  . TYR A 1 326 ? 30.49547  17.82561  -18.90617 1.000 23.40495  ?  326 TYR A OH  1 
ATOM   2441 N  N   . ASP A 1 327 ? 32.80150  12.65772  -18.16073 1.000 24.85891  ?  327 ASP A N   1 
ATOM   2442 C  CA  . ASP A 1 327 ? 32.84660  12.20773  -19.54379 1.000 21.69981  ?  327 ASP A CA  1 
ATOM   2443 C  C   . ASP A 1 327 ? 31.90375  13.07245  -20.36629 1.000 18.19097  ?  327 ASP A C   1 
ATOM   2444 O  O   . ASP A 1 327 ? 30.85418  13.50017  -19.88220 1.000 17.24890  ?  327 ASP A O   1 
ATOM   2445 C  CB  . ASP A 1 327 ? 32.45670  10.72756  -19.66139 1.000 21.44549  ?  327 ASP A CB  1 
ATOM   2446 C  CG  . ASP A 1 327 ? 32.54757  10.20224  -21.08509 1.000 22.43176  ?  327 ASP A CG  1 
ATOM   2447 O  OD1 . ASP A 1 327 ? 33.24057  10.82080  -21.91788 1.000 19.92811  ?  327 ASP A OD1 1 
ATOM   2448 O  OD2 . ASP A 1 327 ? 31.92782  9.15595   -21.37157 1.000 22.15079  -1 327 ASP A OD2 1 
ATOM   2449 N  N   . LEU A 1 328 ? 32.28958  13.33335  -21.61059 1.000 16.04901  ?  328 LEU A N   1 
ATOM   2450 C  CA  . LEU A 1 328 ? 31.45969  14.06888  -22.55458 1.000 18.38763  ?  328 LEU A CA  1 
ATOM   2451 C  C   . LEU A 1 328 ? 30.90269  13.09052  -23.57980 1.000 18.39648  ?  328 LEU A C   1 
ATOM   2452 O  O   . LEU A 1 328 ? 31.66309  12.46915  -24.33137 1.000 15.84958  ?  328 LEU A O   1 
ATOM   2453 C  CB  . LEU A 1 328 ? 32.25627  15.18472  -23.22959 1.000 24.37056  ?  328 LEU A CB  1 
ATOM   2454 C  CG  . LEU A 1 328 ? 32.56327  16.37027  -22.31129 1.000 15.81757  ?  328 LEU A CG  1 
ATOM   2455 C  CD1 . LEU A 1 328 ? 33.65025  17.25135  -22.89908 1.000 15.32459  ?  328 LEU A CD1 1 
ATOM   2456 C  CD2 . LEU A 1 328 ? 31.30059  17.17668  -22.04806 1.000 11.35064  ?  328 LEU A CD2 1 
ATOM   2457 N  N   . VAL A 1 329 ? 29.57713  12.96347  -23.60602 1.000 16.45734  ?  329 VAL A N   1 
ATOM   2458 C  CA  . VAL A 1 329 ? 28.87898  12.02455  -24.47491 1.000 16.71006  ?  329 VAL A CA  1 
ATOM   2459 C  C   . VAL A 1 329 ? 28.01048  12.80747  -25.44895 1.000 15.57090  ?  329 VAL A C   1 
ATOM   2460 O  O   . VAL A 1 329 ? 27.97641  14.04177  -25.41653 1.000 13.96682  ?  329 VAL A O   1 
ATOM   2461 C  CB  . VAL A 1 329 ? 28.03527  11.02508  -23.66248 1.000 16.30361  ?  329 VAL A CB  1 
ATOM   2462 C  CG1 . VAL A 1 329 ? 28.90122  10.30191  -22.64454 1.000 17.42910  ?  329 VAL A CG1 1 
ATOM   2463 C  CG2 . VAL A 1 329 ? 26.87984  11.73774  -22.97874 1.000 22.24043  ?  329 VAL A CG2 1 
ATOM   2464 N  N   . GLY A 1 330 ? 27.29624  12.09550  -26.30783 1.000 21.22029  ?  330 GLY A N   1 
ATOM   2465 C  CA  . GLY A 1 330 ? 26.60108  12.68286  -27.43074 1.000 18.01032  ?  330 GLY A CA  1 
ATOM   2466 C  C   . GLY A 1 330 ? 27.33240  12.41693  -28.73509 1.000 21.77122  ?  330 GLY A C   1 
ATOM   2467 O  O   . GLY A 1 330 ? 28.51638  12.06915  -28.76261 1.000 25.11226  ?  330 GLY A O   1 
ATOM   2468 N  N   . GLN A 1 331 ? 26.60487  12.57338  -29.84069 1.000 14.99815  ?  331 GLN A N   1 
ATOM   2469 C  CA  . GLN A 1 331 ? 27.18603  12.28223  -31.14574 1.000 15.52645  ?  331 GLN A CA  1 
ATOM   2470 C  C   . GLN A 1 331 ? 28.41189  13.15590  -31.38514 1.000 18.86846  ?  331 GLN A C   1 
ATOM   2471 O  O   . GLN A 1 331 ? 28.33880  14.38677  -31.31671 1.000 18.25460  ?  331 GLN A O   1 
ATOM   2472 C  CB  . GLN A 1 331 ? 26.15440  12.49778  -32.25136 1.000 15.67031  ?  331 GLN A CB  1 
ATOM   2473 C  CG  . GLN A 1 331 ? 26.55493  11.87483  -33.57845 1.000 19.06060  ?  331 GLN A CG  1 
ATOM   2474 C  CD  . GLN A 1 331 ? 25.61417  12.24405  -34.70597 1.000 20.97150  ?  331 GLN A CD  1 
ATOM   2475 O  OE1 . GLN A 1 331 ? 25.81736  11.84667  -35.85483 1.000 18.14449  ?  331 GLN A OE1 1 
ATOM   2476 N  NE2 . GLN A 1 331 ? 24.57813  13.01009  -34.38493 1.000 16.53505  ?  331 GLN A NE2 1 
ATOM   2477 N  N   . GLU A 1 332 ? 29.54177  12.50751  -31.66614 1.000 20.92181  ?  332 GLU A N   1 
ATOM   2478 C  CA  . GLU A 1 332 ? 30.83428  13.17980  -31.70034 1.000 18.36846  ?  332 GLU A CA  1 
ATOM   2479 C  C   . GLU A 1 332 ? 31.12518  13.87848  -33.02220 1.000 15.16684  ?  332 GLU A C   1 
ATOM   2480 O  O   . GLU A 1 332 ? 31.81401  14.90564  -33.02669 1.000 16.14436  ?  332 GLU A O   1 
ATOM   2481 C  CB  . GLU A 1 332 ? 31.95093  12.17241  -31.40767 1.000 14.33437  ?  332 GLU A CB  1 
ATOM   2482 C  CG  . GLU A 1 332 ? 33.22098  12.79639  -30.86449 1.000 17.51517  ?  332 GLU A CG  1 
ATOM   2483 C  CD  . GLU A 1 332 ? 34.25584  11.76140  -30.47830 1.000 22.97172  ?  332 GLU A CD  1 
ATOM   2484 O  OE1 . GLU A 1 332 ? 33.93868  10.55537  -30.53814 1.000 24.17868  ?  332 GLU A OE1 1 
ATOM   2485 O  OE2 . GLU A 1 332 ? 35.38515  12.15362  -30.11449 1.000 27.35844  -1 332 GLU A OE2 1 
ATOM   2486 N  N   . ASP A 1 333 ? 30.62743  13.35071  -34.14064 1.000 16.37453  ?  333 ASP A N   1 
ATOM   2487 C  CA  . ASP A 1 333 ? 30.92691  13.95586  -35.43803 1.000 16.50632  ?  333 ASP A CA  1 
ATOM   2488 C  C   . ASP A 1 333 ? 30.38900  15.37548  -35.58484 1.000 18.83414  ?  333 ASP A C   1 
ATOM   2489 O  O   . ASP A 1 333 ? 31.17327  16.26852  -35.94969 1.000 15.35953  ?  333 ASP A O   1 
ATOM   2490 C  CB  . ASP A 1 333 ? 30.41571  13.04977  -36.56630 1.000 21.09133  ?  333 ASP A CB  1 
ATOM   2491 C  CG  . ASP A 1 333 ? 31.42352  11.99179  -36.97025 1.000 22.29718  ?  333 ASP A CG  1 
ATOM   2492 O  OD1 . ASP A 1 333 ? 32.63411  12.21935  -36.77074 1.000 22.13155  ?  333 ASP A OD1 1 
ATOM   2493 O  OD2 . ASP A 1 333 ? 31.00597  10.93664  -37.49382 1.000 17.39200  -1 333 ASP A OD2 1 
ATOM   2494 N  N   . PRO A 1 334 ? 29.11069  15.66627  -35.33566 1.000 20.70856  ?  334 PRO A N   1 
ATOM   2495 C  CA  . PRO A 1 334 ? 28.59017  17.01495  -35.61720 1.000 20.34159  ?  334 PRO A CA  1 
ATOM   2496 C  C   . PRO A 1 334 ? 28.58280  17.98587  -34.44199 1.000 19.18728  ?  334 PRO A C   1 
ATOM   2497 O  O   . PRO A 1 334 ? 28.11800  19.11669  -34.62175 1.000 22.79053  ?  334 PRO A O   1 
ATOM   2498 C  CB  . PRO A 1 334 ? 27.15476  16.70646  -36.05310 1.000 19.26727  ?  334 PRO A CB  1 
ATOM   2499 C  CG  . PRO A 1 334 ? 26.76516  15.57731  -35.16759 1.000 17.73483  ?  334 PRO A CG  1 
ATOM   2500 C  CD  . PRO A 1 334 ? 28.02121  14.76728  -34.90822 1.000 16.58854  ?  334 PRO A CD  1 
ATOM   2501 N  N   . ASN A 1 335 ? 29.06860  17.59349  -33.26963 1.000 17.91468  ?  335 ASN A N   1 
ATOM   2502 C  CA  . ASN A 1 335 ? 29.04202  18.44276  -32.08757 1.000 16.58556  ?  335 ASN A CA  1 
ATOM   2503 C  C   . ASN A 1 335 ? 30.45933  18.86915  -31.71279 1.000 15.00592  ?  335 ASN A C   1 
ATOM   2504 O  O   . ASN A 1 335 ? 31.43302  18.55588  -32.40402 1.000 15.07137  ?  335 ASN A O   1 
ATOM   2505 C  CB  . ASN A 1 335 ? 28.34418  17.72672  -30.92959 1.000 22.25912  ?  335 ASN A CB  1 
ATOM   2506 C  CG  . ASN A 1 335 ? 26.85607  17.54722  -31.17071 1.000 17.83613  ?  335 ASN A CG  1 
ATOM   2507 O  OD1 . ASN A 1 335 ? 26.25057  18.27758  -31.95604 1.000 13.74091  ?  335 ASN A OD1 1 
ATOM   2508 N  ND2 . ASN A 1 335 ? 26.25844  16.57568  -30.49142 1.000 18.13114  ?  335 ASN A ND2 1 
ATOM   2509 N  N   . PHE A 1 336 ? 30.56389  19.59138  -30.59722 1.000 14.83810  ?  336 PHE A N   1 
ATOM   2510 C  CA  . PHE A 1 336 ? 31.82513  20.21411  -30.21594 1.000 20.58340  ?  336 PHE A CA  1 
ATOM   2511 C  C   . PHE A 1 336 ? 32.88986  19.16666  -29.91240 1.000 22.65976  ?  336 PHE A C   1 
ATOM   2512 O  O   . PHE A 1 336 ? 32.59488  18.04593  -29.48770 1.000 25.58191  ?  336 PHE A O   1 
ATOM   2513 C  CB  . PHE A 1 336 ? 31.63799  21.11730  -28.99540 1.000 23.44011  ?  336 PHE A CB  1 
ATOM   2514 C  CG  . PHE A 1 336 ? 30.77171  22.31781  -29.24809 1.000 20.82000  ?  336 PHE A CG  1 
ATOM   2515 C  CD1 . PHE A 1 336 ? 31.11424  23.24472  -30.21703 1.000 16.61324  ?  336 PHE A CD1 1 
ATOM   2516 C  CD2 . PHE A 1 336 ? 29.62784  22.53203  -28.49718 1.000 19.44833  ?  336 PHE A CD2 1 
ATOM   2517 C  CE1 . PHE A 1 336 ? 30.32303  24.35279  -30.44346 1.000 17.04807  ?  336 PHE A CE1 1 
ATOM   2518 C  CE2 . PHE A 1 336 ? 28.83323  23.63867  -28.71711 1.000 18.75485  ?  336 PHE A CE2 1 
ATOM   2519 C  CZ  . PHE A 1 336 ? 29.18076  24.55027  -29.69164 1.000 22.23757  ?  336 PHE A CZ  1 
ATOM   2520 N  N   . SER A 1 337 ? 34.14222  19.54847  -30.13936 1.000 19.19156  ?  337 SER A N   1 
ATOM   2521 C  CA  . SER A 1 337 ? 35.28333  18.68972  -29.87455 1.000 19.50053  ?  337 SER A CA  1 
ATOM   2522 C  C   . SER A 1 337 ? 35.72256  18.80933  -28.41836 1.000 19.78013  ?  337 SER A C   1 
ATOM   2523 O  O   . SER A 1 337 ? 35.24462  19.65620  -27.66050 1.000 18.52547  ?  337 SER A O   1 
ATOM   2524 C  CB  . SER A 1 337 ? 36.44421  19.04460  -30.79986 1.000 19.83729  ?  337 SER A CB  1 
ATOM   2525 O  OG  . SER A 1 337 ? 36.88256  20.37327  -30.57615 1.000 17.67741  ?  337 SER A OG  1 
ATOM   2526 N  N   . LEU A 1 338 ? 36.65281  17.93398  -28.03013 1.000 26.69624  ?  338 LEU A N   1 
ATOM   2527 C  CA  . LEU A 1 338 ? 37.24599  18.03008  -26.70100 1.000 22.47190  ?  338 LEU A CA  1 
ATOM   2528 C  C   . LEU A 1 338 ? 38.01999  19.33145  -26.54055 1.000 25.21976  ?  338 LEU A C   1 
ATOM   2529 O  O   . LEU A 1 338 ? 38.01193  19.93915  -25.46363 1.000 32.01232  ?  338 LEU A O   1 
ATOM   2530 C  CB  . LEU A 1 338 ? 38.15713  16.83070  -26.43922 1.000 22.73916  ?  338 LEU A CB  1 
ATOM   2531 C  CG  . LEU A 1 338 ? 37.48221  15.47658  -26.22072 1.000 25.64134  ?  338 LEU A CG  1 
ATOM   2532 C  CD1 . LEU A 1 338 ? 38.51238  14.42794  -25.83005 1.000 26.61941  ?  338 LEU A CD1 1 
ATOM   2533 C  CD2 . LEU A 1 338 ? 36.39614  15.58620  -25.16277 1.000 30.69059  ?  338 LEU A CD2 1 
ATOM   2534 N  N   . LEU A 1 339 ? 38.69876  19.77294  -27.60276 1.000 22.19517  ?  339 LEU A N   1 
ATOM   2535 C  CA  . LEU A 1 339 ? 39.46969  21.00958  -27.53015 1.000 25.80175  ?  339 LEU A CA  1 
ATOM   2536 C  C   . LEU A 1 339 ? 38.57213  22.22026  -27.30536 1.000 26.29579  ?  339 LEU A C   1 
ATOM   2537 O  O   . LEU A 1 339 ? 38.97032  23.16785  -26.61748 1.000 27.71943  ?  339 LEU A O   1 
ATOM   2538 C  CB  . LEU A 1 339 ? 40.29471  21.18595  -28.80501 1.000 23.77922  ?  339 LEU A CB  1 
ATOM   2539 C  CG  . LEU A 1 339 ? 41.32110  22.31924  -28.79821 1.000 15.66708  ?  339 LEU A CG  1 
ATOM   2540 C  CD1 . LEU A 1 339 ? 42.35628  22.08828  -27.71100 1.000 22.05412  ?  339 LEU A CD1 1 
ATOM   2541 C  CD2 . LEU A 1 339 ? 41.98748  22.44836  -30.15730 1.000 14.61409  ?  339 LEU A CD2 1 
ATOM   2542 N  N   . HIS A 1 340 ? 37.36185  22.20648  -27.87241 1.000 22.20842  ?  340 HIS A N   1 
ATOM   2543 C  CA  . HIS A 1 340 ? 36.43750  23.32330  -27.69709 1.000 20.12708  ?  340 HIS A CA  1 
ATOM   2544 C  C   . HIS A 1 340 ? 36.06716  23.52862  -26.23270 1.000 22.27693  ?  340 HIS A C   1 
ATOM   2545 O  O   . HIS A 1 340 ? 35.73913  24.64961  -25.82713 1.000 26.50026  ?  340 HIS A O   1 
ATOM   2546 C  CB  . HIS A 1 340 ? 35.18363  23.09212  -28.54173 1.000 20.92765  ?  340 HIS A CB  1 
ATOM   2547 C  CG  . HIS A 1 340 ? 34.07833  24.06389  -28.26887 1.000 17.99968  ?  340 HIS A CG  1 
ATOM   2548 N  ND1 . HIS A 1 340 ? 33.00164  23.75798  -27.46475 1.000 19.83157  ?  340 HIS A ND1 1 
ATOM   2549 C  CD2 . HIS A 1 340 ? 33.87996  25.33326  -28.69583 1.000 20.00854  ?  340 HIS A CD2 1 
ATOM   2550 C  CE1 . HIS A 1 340 ? 32.18737  24.79650  -27.40812 1.000 18.89299  ?  340 HIS A CE1 1 
ATOM   2551 N  NE2 . HIS A 1 340 ? 32.69780  25.76610  -28.14547 1.000 21.23100  ?  340 HIS A NE2 1 
ATOM   2552 N  N   . TYR A 1 341 ? 36.11931  22.46873  -25.42776 1.000 19.96079  ?  341 TYR A N   1 
ATOM   2553 C  CA  . TYR A 1 341 ? 35.85450  22.54026  -23.99739 1.000 22.42931  ?  341 TYR A CA  1 
ATOM   2554 C  C   . TYR A 1 341 ? 37.13198  22.60043  -23.17013 1.000 26.55554  ?  341 TYR A C   1 
ATOM   2555 O  O   . TYR A 1 341 ? 37.07221  22.43100  -21.94537 1.000 24.26129  ?  341 TYR A O   1 
ATOM   2556 C  CB  . TYR A 1 341 ? 35.01631  21.33938  -23.55653 1.000 21.54037  ?  341 TYR A CB  1 
ATOM   2557 C  CG  . TYR A 1 341 ? 33.62310  21.29648  -24.13860 1.000 14.94460  ?  341 TYR A CG  1 
ATOM   2558 C  CD1 . TYR A 1 341 ? 32.78454  22.39956  -24.07212 1.000 14.49849  ?  341 TYR A CD1 1 
ATOM   2559 C  CD2 . TYR A 1 341 ? 33.14768  20.14927  -24.75620 1.000 20.65065  ?  341 TYR A CD2 1 
ATOM   2560 C  CE1 . TYR A 1 341 ? 31.50954  22.35830  -24.60274 1.000 16.57971  ?  341 TYR A CE1 1 
ATOM   2561 C  CE2 . TYR A 1 341 ? 31.87766  20.09776  -25.28768 1.000 17.64411  ?  341 TYR A CE2 1 
ATOM   2562 C  CZ  . TYR A 1 341 ? 31.06274  21.20333  -25.20844 1.000 18.05477  ?  341 TYR A CZ  1 
ATOM   2563 O  OH  . TYR A 1 341 ? 29.79713  21.14634  -25.74005 1.000 22.61217  ?  341 TYR A OH  1 
ATOM   2564 N  N   . LEU A 1 342 ? 38.27689  22.85771  -23.81244 1.000 26.82269  ?  342 LEU A N   1 
ATOM   2565 C  CA  . LEU A 1 342 ? 39.57563  22.66088  -23.17243 1.000 29.04721  ?  342 LEU A CA  1 
ATOM   2566 C  C   . LEU A 1 342 ? 39.66697  23.37630  -21.83105 1.000 29.17499  ?  342 LEU A C   1 
ATOM   2567 O  O   . LEU A 1 342 ? 40.07774  22.77968  -20.82920 1.000 28.93817  ?  342 LEU A O   1 
ATOM   2568 C  CB  . LEU A 1 342 ? 40.69490  23.13240  -24.10006 1.000 21.74522  ?  342 LEU A CB  1 
ATOM   2569 C  CG  . LEU A 1 342 ? 42.08667  23.05833  -23.47090 1.000 23.61411  ?  342 LEU A CG  1 
ATOM   2570 C  CD1 . LEU A 1 342 ? 42.39398  21.63220  -23.03719 1.000 26.70399  ?  342 LEU A CD1 1 
ATOM   2571 C  CD2 . LEU A 1 342 ? 43.14770  23.57990  -24.42576 1.000 24.64951  ?  342 LEU A CD2 1 
ATOM   2572 N  N   . ASP A 1 343 ? 39.27843  24.65449  -21.79193 1.000 28.19575  ?  343 ASP A N   1 
ATOM   2573 C  CA  . ASP A 1 343 ? 39.31685  25.41157  -20.54407 1.000 27.57332  ?  343 ASP A CA  1 
ATOM   2574 C  C   . ASP A 1 343 ? 38.64879  24.63373  -19.41741 1.000 29.27627  ?  343 ASP A C   1 
ATOM   2575 O  O   . ASP A 1 343 ? 39.26668  24.35152  -18.38301 1.000 23.43437  ?  343 ASP A O   1 
ATOM   2576 C  CB  . ASP A 1 343 ? 38.63563  26.77146  -20.72797 1.000 27.87948  ?  343 ASP A CB  1 
ATOM   2577 C  CG  . ASP A 1 343 ? 39.45060  27.73072  -21.57525 1.000 29.29025  ?  343 ASP A CG  1 
ATOM   2578 O  OD1 . ASP A 1 343 ? 40.43193  27.29254  -22.21049 1.000 29.74214  ?  343 ASP A OD1 1 
ATOM   2579 O  OD2 . ASP A 1 343 ? 39.10821  28.93210  -21.59960 1.000 32.44101  -1 343 ASP A OD2 1 
ATOM   2580 N  N   . ALA A 1 344 ? 37.39605  24.22384  -19.63710 1.000 29.16013  ?  344 ALA A N   1 
ATOM   2581 C  CA  . ALA A 1 344 ? 36.65918  23.50621  -18.60330 1.000 22.87791  ?  344 ALA A CA  1 
ATOM   2582 C  C   . ALA A 1 344 ? 37.37023  22.21859  -18.21425 1.000 35.10704  ?  344 ALA A C   1 
ATOM   2583 O  O   . ALA A 1 344 ? 37.38974  21.84239  -17.03620 1.000 38.51596  ?  344 ALA A O   1 
ATOM   2584 C  CB  . ALA A 1 344 ? 35.23924  23.21057  -19.08095 1.000 18.01124  ?  344 ALA A CB  1 
ATOM   2585 N  N   . LEU A 1 345 ? 37.96861  21.53206  -19.18884 1.000 30.87545  ?  345 LEU A N   1 
ATOM   2586 C  CA  . LEU A 1 345 ? 38.65732  20.28474  -18.89231 1.000 30.17429  ?  345 LEU A CA  1 
ATOM   2587 C  C   . LEU A 1 345 ? 40.01536  20.50633  -18.24008 1.000 30.49151  ?  345 LEU A C   1 
ATOM   2588 O  O   . LEU A 1 345 ? 40.54730  19.57989  -17.61886 1.000 29.19257  ?  345 LEU A O   1 
ATOM   2589 C  CB  . LEU A 1 345 ? 38.80946  19.45773  -20.17036 1.000 31.41296  ?  345 LEU A CB  1 
ATOM   2590 C  CG  . LEU A 1 345 ? 37.48068  19.02716  -20.79766 1.000 33.08133  ?  345 LEU A CG  1 
ATOM   2591 C  CD1 . LEU A 1 345 ? 37.70548  18.28752  -22.10574 1.000 32.71970  ?  345 LEU A CD1 1 
ATOM   2592 C  CD2 . LEU A 1 345 ? 36.67828  18.17194  -19.82414 1.000 23.73102  ?  345 LEU A CD2 1 
ATOM   2593 N  N   . LEU A 1 346 ? 40.58635  21.70401  -18.36094 1.000 29.66153  ?  346 LEU A N   1 
ATOM   2594 C  CA  . LEU A 1 346 ? 41.84278  22.01078  -17.69351 1.000 29.59574  ?  346 LEU A CA  1 
ATOM   2595 C  C   . LEU A 1 346 ? 41.64183  22.65801  -16.33278 1.000 33.24456  ?  346 LEU A C   1 
ATOM   2596 O  O   . LEU A 1 346 ? 42.61924  22.83231  -15.59680 1.000 29.20522  ?  346 LEU A O   1 
ATOM   2597 C  CB  . LEU A 1 346 ? 42.70615  22.92540  -18.57007 1.000 23.45661  ?  346 LEU A CB  1 
ATOM   2598 C  CG  . LEU A 1 346 ? 43.63256  22.23196  -19.56871 1.000 19.38041  ?  346 LEU A CG  1 
ATOM   2599 C  CD1 . LEU A 1 346 ? 44.46068  23.25512  -20.32575 1.000 18.85253  ?  346 LEU A CD1 1 
ATOM   2600 C  CD2 . LEU A 1 346 ? 44.53236  21.23320  -18.85762 1.000 25.16421  ?  346 LEU A CD2 1 
ATOM   2601 N  N   . TYR A 1 347 ? 40.40399  23.00535  -15.98463 1.000 32.36756  ?  347 TYR A N   1 
ATOM   2602 C  CA  . TYR A 1 347 ? 40.14851  23.66227  -14.70669 1.000 30.73376  ?  347 TYR A CA  1 
ATOM   2603 C  C   . TYR A 1 347 ? 40.63364  22.85903  -13.50409 1.000 34.07569  ?  347 TYR A C   1 
ATOM   2604 O  O   . TYR A 1 347 ? 41.23057  23.46787  -12.59905 1.000 36.23839  ?  347 TYR A O   1 
ATOM   2605 C  CB  . TYR A 1 347 ? 38.65334  23.98746  -14.58783 1.000 30.61288  ?  347 TYR A CB  1 
ATOM   2606 C  CG  . TYR A 1 347 ? 38.29024  24.75514  -13.33865 1.000 34.95861  ?  347 TYR A CG  1 
ATOM   2607 C  CD1 . TYR A 1 347 ? 38.57741  26.10893  -13.22499 1.000 34.94569  ?  347 TYR A CD1 1 
ATOM   2608 C  CD2 . TYR A 1 347 ? 37.65531  24.12827  -12.27524 1.000 36.15846  ?  347 TYR A CD2 1 
ATOM   2609 C  CE1 . TYR A 1 347 ? 38.24696  26.81611  -12.08515 1.000 36.33583  ?  347 TYR A CE1 1 
ATOM   2610 C  CE2 . TYR A 1 347 ? 37.32000  24.82703  -11.13132 1.000 36.83603  ?  347 TYR A CE2 1 
ATOM   2611 C  CZ  . TYR A 1 347 ? 37.61801  26.17043  -11.04203 1.000 39.79335  ?  347 TYR A CZ  1 
ATOM   2612 O  OH  . TYR A 1 347 ? 37.28655  26.87088  -9.90544  1.000 40.33305  ?  347 TYR A OH  1 
ATOM   2613 N  N   . PRO A 1 348 ? 40.41632  21.53910  -13.40821 1.000 41.73913  ?  348 PRO A N   1 
ATOM   2614 C  CA  . PRO A 1 348 ? 40.97720  20.80946  -12.25647 1.000 35.36239  ?  348 PRO A CA  1 
ATOM   2615 C  C   . PRO A 1 348 ? 42.49087  20.90026  -12.15053 1.000 32.59850  ?  348 PRO A C   1 
ATOM   2616 O  O   . PRO A 1 348 ? 43.02087  20.99398  -11.03715 1.000 27.13196  ?  348 PRO A O   1 
ATOM   2617 C  CB  . PRO A 1 348 ? 40.51205  19.36671  -12.49939 1.000 28.31073  ?  348 PRO A CB  1 
ATOM   2618 C  CG  . PRO A 1 348 ? 39.29161  19.50091  -13.32957 1.000 28.36956  ?  348 PRO A CG  1 
ATOM   2619 C  CD  . PRO A 1 348 ? 39.55413  20.66778  -14.22964 1.000 36.48917  ?  348 PRO A CD  1 
ATOM   2620 N  N   . SER A 1 349 ? 43.20576  20.88833  -13.27770 1.000 31.26932  ?  349 SER A N   1 
ATOM   2621 C  CA  . SER A 1 349 ? 44.66281  20.83380  -13.23767 1.000 36.69021  ?  349 SER A CA  1 
ATOM   2622 C  C   . SER A 1 349 ? 45.31067  22.17761  -12.92325 1.000 42.41783  ?  349 SER A C   1 
ATOM   2623 O  O   . SER A 1 349 ? 46.45386  22.19891  -12.45346 1.000 33.14988  ?  349 SER A O   1 
ATOM   2624 C  CB  . SER A 1 349 ? 45.20854  20.30575  -14.56632 1.000 38.12899  ?  349 SER A CB  1 
ATOM   2625 O  OG  . SER A 1 349 ? 44.98404  21.23090  -15.61499 1.000 39.12595  ?  349 SER A OG  1 
ATOM   2626 N  N   . ILE A 1 350 ? 44.61871  23.29650  -13.16934 1.000 41.40405  ?  350 ILE A N   1 
ATOM   2627 C  CA  . ILE A 1 350 ? 45.20724  24.61360  -12.92398 1.000 36.26018  ?  350 ILE A CA  1 
ATOM   2628 C  C   . ILE A 1 350 ? 45.10302  25.04753  -11.47334 1.000 36.49538  ?  350 ILE A C   1 
ATOM   2629 O  O   . ILE A 1 350 ? 45.60457  26.12419  -11.12330 1.000 33.46561  ?  350 ILE A O   1 
ATOM   2630 C  CB  . ILE A 1 350 ? 44.55725  25.71139  -13.79011 1.000 34.10021  ?  350 ILE A CB  1 
ATOM   2631 C  CG1 . ILE A 1 350 ? 43.11555  25.95999  -13.34207 1.000 38.60065  ?  350 ILE A CG1 1 
ATOM   2632 C  CG2 . ILE A 1 350 ? 44.61703  25.33733  -15.26234 1.000 34.46754  ?  350 ILE A CG2 1 
ATOM   2633 C  CD1 . ILE A 1 350 ? 42.46062  27.14254  -14.01827 1.000 37.87927  ?  350 ILE A CD1 1 
ATOM   2634 N  N   . GLN A 1 351 ? 44.46811  24.25051  -10.61975 1.000 38.54485  ?  351 GLN A N   1 
ATOM   2635 C  CA  . GLN A 1 351 ? 44.30241  24.62346  -9.22547  1.000 36.72017  ?  351 GLN A CA  1 
ATOM   2636 C  C   . GLN A 1 351 ? 45.63886  24.56209  -8.48910  1.000 36.26149  ?  351 GLN A C   1 
ATOM   2637 O  O   . GLN A 1 351 ? 46.61485  23.96934  -8.95682  1.000 36.04538  ?  351 GLN A O   1 
ATOM   2638 C  CB  . GLN A 1 351 ? 43.28196  23.70888  -8.54747  1.000 34.24222  ?  351 GLN A CB  1 
ATOM   2639 C  CG  . GLN A 1 351 ? 41.94994  23.61614  -9.27908  1.000 32.96373  ?  351 GLN A CG  1 
ATOM   2640 C  CD  . GLN A 1 351 ? 41.18198  24.92390  -9.26829  1.000 37.60192  ?  351 GLN A CD  1 
ATOM   2641 O  OE1 . GLN A 1 351 ? 41.05393  25.57334  -8.23035  1.000 51.90494  ?  351 GLN A OE1 1 
ATOM   2642 N  NE2 . GLN A 1 351 ? 40.66896  25.31889  -10.42776 1.000 31.53417  ?  351 GLN A NE2 1 
ATOM   2643 N  N   . ASN A 1 352 ? 45.67683  25.20860  -7.32716  1.000 36.77728  ?  352 ASN A N   1 
ATOM   2644 C  CA  . ASN A 1 352 ? 46.85279  25.21768  -6.45858  1.000 40.12292  ?  352 ASN A CA  1 
ATOM   2645 C  C   . ASN A 1 352 ? 46.42554  24.77431  -5.06598  1.000 36.54112  ?  352 ASN A C   1 
ATOM   2646 O  O   . ASN A 1 352 ? 45.89516  25.58818  -4.28942  1.000 37.30343  ?  352 ASN A O   1 
ATOM   2647 C  CB  . ASN A 1 352 ? 47.50379  26.59497  -6.41712  1.000 39.58286  ?  352 ASN A CB  1 
ATOM   2648 C  CG  . ASN A 1 352 ? 48.09276  27.00146  -7.75481  1.000 60.79632  ?  352 ASN A CG  1 
ATOM   2649 O  OD1 . ASN A 1 352 ? 48.56626  26.15994  -8.51937  1.000 57.31320  ?  352 ASN A OD1 1 
ATOM   2650 N  ND2 . ASN A 1 352 ? 48.06657  28.29758  -8.04423  1.000 61.04960  ?  352 ASN A ND2 1 
ATOM   2651 N  N   . PRO A 1 353 ? 46.63516  23.49959  -4.70730  1.000 31.31831  ?  353 PRO A N   1 
ATOM   2652 C  CA  . PRO A 1 353 ? 47.27648  22.43185  -5.49050  1.000 25.25713  ?  353 PRO A CA  1 
ATOM   2653 C  C   . PRO A 1 353 ? 46.37794  21.88942  -6.59781  1.000 31.52614  ?  353 PRO A C   1 
ATOM   2654 O  O   . PRO A 1 353 ? 45.15515  21.96676  -6.50269  1.000 28.68347  ?  353 PRO A O   1 
ATOM   2655 C  CB  . PRO A 1 353 ? 47.57498  21.36897  -4.42628  1.000 18.81879  ?  353 PRO A CB  1 
ATOM   2656 C  CG  . PRO A 1 353 ? 46.45865  21.52969  -3.44113  1.000 24.42064  ?  353 PRO A CG  1 
ATOM   2657 C  CD  . PRO A 1 353 ? 46.20338  23.01665  -3.38298  1.000 29.39589  ?  353 PRO A CD  1 
ATOM   2658 N  N   . PRO A 1 354 ? 46.97154  21.35518  -7.66597  1.000 34.41901  ?  354 PRO A N   1 
ATOM   2659 C  CA  . PRO A 1 354 ? 46.16328  20.80417  -8.76041  1.000 29.82148  ?  354 PRO A CA  1 
ATOM   2660 C  C   . PRO A 1 354 ? 45.29465  19.64595  -8.29332  1.000 27.86528  ?  354 PRO A C   1 
ATOM   2661 O  O   . PRO A 1 354 ? 45.70521  18.82459  -7.47033  1.000 19.66513  ?  354 PRO A O   1 
ATOM   2662 C  CB  . PRO A 1 354 ? 47.21259  20.34476  -9.77932  1.000 19.90388  ?  354 PRO A CB  1 
ATOM   2663 C  CG  . PRO A 1 354 ? 48.42426  21.15943  -9.46829  1.000 27.43618  ?  354 PRO A CG  1 
ATOM   2664 C  CD  . PRO A 1 354 ? 48.40986  21.34201  -7.98059  1.000 31.95335  ?  354 PRO A CD  1 
ATOM   2665 N  N   . TYR A 1 355 ? 44.08412  19.58648  -8.83768  1.000 33.75305  ?  355 TYR A N   1 
ATOM   2666 C  CA  . TYR A 1 355 ? 43.14102  18.51740  -8.55011  1.000 29.84125  ?  355 TYR A CA  1 
ATOM   2667 C  C   . TYR A 1 355 ? 43.10637  17.53796  -9.71431  1.000 25.51942  ?  355 TYR A C   1 
ATOM   2668 O  O   . TYR A 1 355 ? 43.16971  17.93842  -10.88045 1.000 25.49475  ?  355 TYR A O   1 
ATOM   2669 C  CB  . TYR A 1 355 ? 41.74016  19.07211  -8.29220  1.000 25.25873  ?  355 TYR A CB  1 
ATOM   2670 C  CG  . TYR A 1 355 ? 40.75260  18.02338  -7.84070  1.000 21.35670  ?  355 TYR A CG  1 
ATOM   2671 C  CD1 . TYR A 1 355 ? 40.70887  17.61211  -6.51649  1.000 22.80636  ?  355 TYR A CD1 1 
ATOM   2672 C  CD2 . TYR A 1 355 ? 39.86580  17.44325  -8.73706  1.000 25.13499  ?  355 TYR A CD2 1 
ATOM   2673 C  CE1 . TYR A 1 355 ? 39.81058  16.65388  -6.09628  1.000 24.81549  ?  355 TYR A CE1 1 
ATOM   2674 C  CE2 . TYR A 1 355 ? 38.96208  16.48313  -8.32579  1.000 27.97987  ?  355 TYR A CE2 1 
ATOM   2675 C  CZ  . TYR A 1 355 ? 38.93929  16.09277  -7.00396  1.000 24.72196  ?  355 TYR A CZ  1 
ATOM   2676 O  OH  . TYR A 1 355 ? 38.04209  15.13823  -6.58613  1.000 24.22426  ?  355 TYR A OH  1 
ATOM   2677 N  N   . ARG A 1 356 ? 43.00212  16.25534  -9.39048  1.000 22.45276  ?  356 ARG A N   1 
ATOM   2678 C  CA  . ARG A 1 356 ? 43.06535  15.17692  -10.37173 1.000 29.28546  ?  356 ARG A CA  1 
ATOM   2679 C  C   . ARG A 1 356 ? 41.65302  14.62855  -10.57139 1.000 31.76795  ?  356 ARG A C   1 
ATOM   2680 O  O   . ARG A 1 356 ? 41.20009  13.75147  -9.83366  1.000 35.13190  ?  356 ARG A O   1 
ATOM   2681 C  CB  . ARG A 1 356 ? 44.03801  14.09614  -9.90834  1.000 42.24721  ?  356 ARG A CB  1 
ATOM   2682 C  CG  . ARG A 1 356 ? 44.22719  12.96015  -10.88909 1.000 61.23361  ?  356 ARG A CG  1 
ATOM   2683 C  CD  . ARG A 1 356 ? 44.77659  13.44897  -12.21685 1.000 52.44567  ?  356 ARG A CD  1 
ATOM   2684 N  NE  . ARG A 1 356 ? 44.90471  12.34407  -13.15726 1.000 54.17583  ?  356 ARG A NE  1 
ATOM   2685 C  CZ  . ARG A 1 356 ? 43.90798  11.87190  -13.89225 1.000 48.13775  ?  356 ARG A CZ  1 
ATOM   2686 N  NH1 . ARG A 1 356 ? 42.70259  12.41527  -13.85275 1.000 52.20460  ?  356 ARG A NH1 1 
ATOM   2687 N  NH2 . ARG A 1 356 ? 44.12375  10.82343  -14.67992 1.000 60.50047  ?  356 ARG A NH2 1 
ATOM   2688 N  N   . LEU A 1 357 ? 40.95642  15.15672  -11.58049 1.000 23.51013  ?  357 LEU A N   1 
ATOM   2689 C  CA  . LEU A 1 357 ? 39.61289  14.70083  -11.90292 1.000 24.01479  ?  357 LEU A CA  1 
ATOM   2690 C  C   . LEU A 1 357 ? 39.69158  13.68663  -13.03230 1.000 28.03336  ?  357 LEU A C   1 
ATOM   2691 O  O   . LEU A 1 357 ? 40.05685  14.05746  -14.15880 1.000 24.61355  ?  357 LEU A O   1 
ATOM   2692 C  CB  . LEU A 1 357 ? 38.72217  15.87503  -12.30320 1.000 23.87172  ?  357 LEU A CB  1 
ATOM   2693 C  CG  . LEU A 1 357 ? 37.24760  15.54293  -12.54548 1.000 19.65029  ?  357 LEU A CG  1 
ATOM   2694 C  CD1 . LEU A 1 357 ? 36.55689  15.17944  -11.23858 1.000 17.98719  ?  357 LEU A CD1 1 
ATOM   2695 C  CD2 . LEU A 1 357 ? 36.53427  16.69550  -13.23687 1.000 18.93863  ?  357 LEU A CD2 1 
ATOM   2696 N  N   . PRO A 1 358 ? 39.36839  12.41765  -12.79286 1.000 25.78498  ?  358 PRO A N   1 
ATOM   2697 C  CA  . PRO A 1 358 ? 39.49804  11.41002  -13.85083 1.000 29.60786  ?  358 PRO A CA  1 
ATOM   2698 C  C   . PRO A 1 358 ? 38.52099  11.65013  -14.99075 1.000 33.89105  ?  358 PRO A C   1 
ATOM   2699 O  O   . PRO A 1 358 ? 37.44559  12.22768  -14.81266 1.000 29.66637  ?  358 PRO A O   1 
ATOM   2700 C  CB  . PRO A 1 358 ? 39.19257  10.09260  -13.12682 1.000 24.52242  ?  358 PRO A CB  1 
ATOM   2701 C  CG  . PRO A 1 358 ? 39.41358  10.39184  -11.67481 1.000 23.52612  ?  358 PRO A CG  1 
ATOM   2702 C  CD  . PRO A 1 358 ? 39.00156  11.81781  -11.50045 1.000 18.48802  ?  358 PRO A CD  1 
ATOM   2703 N  N   . TYR A 1 359 ? 38.91422  11.19194  -16.17713 1.000 32.61800  ?  359 TYR A N   1 
ATOM   2704 C  CA  . TYR A 1 359 ? 38.12068  11.33629  -17.38724 1.000 29.50177  ?  359 TYR A CA  1 
ATOM   2705 C  C   . TYR A 1 359 ? 37.89149  9.97329   -18.02577 1.000 29.07951  ?  359 TYR A C   1 
ATOM   2706 O  O   . TYR A 1 359 ? 38.69961  9.05369   -17.87408 1.000 28.65099  ?  359 TYR A O   1 
ATOM   2707 C  CB  . TYR A 1 359 ? 38.80231  12.27729  -18.38937 1.000 32.10544  ?  359 TYR A CB  1 
ATOM   2708 C  CG  . TYR A 1 359 ? 38.75835  13.73096  -17.97990 1.000 27.38153  ?  359 TYR A CG  1 
ATOM   2709 C  CD1 . TYR A 1 359 ? 37.68949  14.23064  -17.24937 1.000 27.25007  ?  359 TYR A CD1 1 
ATOM   2710 C  CD2 . TYR A 1 359 ? 39.78613  14.60179  -18.31770 1.000 24.15765  ?  359 TYR A CD2 1 
ATOM   2711 C  CE1 . TYR A 1 359 ? 37.64141  15.55572  -16.86996 1.000 30.87675  ?  359 TYR A CE1 1 
ATOM   2712 C  CE2 . TYR A 1 359 ? 39.74645  15.93114  -17.94364 1.000 24.89958  ?  359 TYR A CE2 1 
ATOM   2713 C  CZ  . TYR A 1 359 ? 38.67149  16.40160  -17.21892 1.000 29.80930  ?  359 TYR A CZ  1 
ATOM   2714 O  OH  . TYR A 1 359 ? 38.62246  17.72221  -16.83938 1.000 34.22393  ?  359 TYR A OH  1 
ATOM   2715 N  N   . PHE A 1 360 ? 36.77015  9.84796   -18.72954 1.000 26.34800  ?  360 PHE A N   1 
ATOM   2716 C  CA  . PHE A 1 360 ? 36.38977  8.60677   -19.39916 1.000 21.81925  ?  360 PHE A CA  1 
ATOM   2717 C  C   . PHE A 1 360 ? 35.89392  8.91579   -20.80896 1.000 20.80579  ?  360 PHE A C   1 
ATOM   2718 O  O   . PHE A 1 360 ? 34.84860  8.43515   -21.24754 1.000 18.22863  ?  360 PHE A O   1 
ATOM   2719 C  CB  . PHE A 1 360 ? 35.33881  7.85661   -18.58411 1.000 19.10132  ?  360 PHE A CB  1 
ATOM   2720 C  CG  . PHE A 1 360 ? 35.80262  7.47059   -17.20711 1.000 23.72025  ?  360 PHE A CG  1 
ATOM   2721 C  CD1 . PHE A 1 360 ? 35.64985  8.34026   -16.13971 1.000 24.28758  ?  360 PHE A CD1 1 
ATOM   2722 C  CD2 . PHE A 1 360 ? 36.39116  6.23748   -16.97975 1.000 25.67892  ?  360 PHE A CD2 1 
ATOM   2723 C  CE1 . PHE A 1 360 ? 36.07443  7.98768   -14.87242 1.000 24.39275  ?  360 PHE A CE1 1 
ATOM   2724 C  CE2 . PHE A 1 360 ? 36.81789  5.87897   -15.71365 1.000 22.02531  ?  360 PHE A CE2 1 
ATOM   2725 C  CZ  . PHE A 1 360 ? 36.65905  6.75550   -14.65955 1.000 22.28319  ?  360 PHE A CZ  1 
ATOM   2726 N  N   . PHE A 1 361 ? 36.67022  9.71890   -21.53594 1.000 18.84057  ?  361 PHE A N   1 
ATOM   2727 C  CA  . PHE A 1 361 ? 36.21111  10.32845  -22.77959 1.000 17.64604  ?  361 PHE A CA  1 
ATOM   2728 C  C   . PHE A 1 361 ? 35.79691  9.29857   -23.82470 1.000 16.87101  ?  361 PHE A C   1 
ATOM   2729 O  O   . PHE A 1 361 ? 36.53186  8.34748   -24.10445 1.000 17.99720  ?  361 PHE A O   1 
ATOM   2730 C  CB  . PHE A 1 361 ? 37.31764  11.21114  -23.35582 1.000 20.55255  ?  361 PHE A CB  1 
ATOM   2731 C  CG  . PHE A 1 361 ? 37.54210  12.48207  -22.59552 1.000 24.42890  ?  361 PHE A CG  1 
ATOM   2732 C  CD1 . PHE A 1 361 ? 36.47093  13.23955  -22.15359 1.000 25.26054  ?  361 PHE A CD1 1 
ATOM   2733 C  CD2 . PHE A 1 361 ? 38.82670  12.92200  -22.32535 1.000 23.06444  ?  361 PHE A CD2 1 
ATOM   2734 C  CE1 . PHE A 1 361 ? 36.67712  14.41301  -21.45605 1.000 27.43154  ?  361 PHE A CE1 1 
ATOM   2735 C  CE2 . PHE A 1 361 ? 39.03912  14.09240  -21.62869 1.000 24.54802  ?  361 PHE A CE2 1 
ATOM   2736 C  CZ  . PHE A 1 361 ? 37.96309  14.83964  -21.19299 1.000 27.42867  ?  361 PHE A CZ  1 
ATOM   2737 N  N   . HIS A 1 362 ? 34.61546  9.50268   -24.41036 1.000 18.30964  ?  362 HIS A N   1 
ATOM   2738 C  CA  . HIS A 1 362 ? 34.33277  8.94751   -25.72755 1.000 18.18729  ?  362 HIS A CA  1 
ATOM   2739 C  C   . HIS A 1 362 ? 35.23910  9.64478   -26.73496 1.000 22.48750  ?  362 HIS A C   1 
ATOM   2740 O  O   . HIS A 1 362 ? 35.27057  10.87699  -26.79805 1.000 25.45339  ?  362 HIS A O   1 
ATOM   2741 C  CB  . HIS A 1 362 ? 32.86443  9.15969   -26.11327 1.000 19.22208  ?  362 HIS A CB  1 
ATOM   2742 C  CG  . HIS A 1 362 ? 31.89218  8.27512   -25.38858 1.000 20.36926  ?  362 HIS A CG  1 
ATOM   2743 N  ND1 . HIS A 1 362 ? 31.70989  8.32356   -24.02333 1.000 17.86446  ?  362 HIS A ND1 1 
ATOM   2744 C  CD2 . HIS A 1 362 ? 31.02166  7.34330   -25.84938 1.000 19.69120  ?  362 HIS A CD2 1 
ATOM   2745 C  CE1 . HIS A 1 362 ? 30.78222  7.44941   -23.67241 1.000 19.46547  ?  362 HIS A CE1 1 
ATOM   2746 N  NE2 . HIS A 1 362 ? 30.34828  6.83899   -24.76153 1.000 22.25883  ?  362 HIS A NE2 1 
ATOM   2747 N  N   . ALA A 1 363 ? 35.98791  8.87217   -27.51769 1.000 19.54667  ?  363 ALA A N   1 
ATOM   2748 C  CA  . ALA A 1 363 ? 36.99021  9.46900   -28.39112 1.000 16.80748  ?  363 ALA A CA  1 
ATOM   2749 C  C   . ALA A 1 363 ? 37.05404  8.73539   -29.71995 1.000 16.07903  ?  363 ALA A C   1 
ATOM   2750 O  O   . ALA A 1 363 ? 37.08068  7.50169   -29.75105 1.000 22.10480  ?  363 ALA A O   1 
ATOM   2751 C  CB  . ALA A 1 363 ? 38.37033  9.46715   -27.72371 1.000 15.85816  ?  363 ALA A CB  1 
ATOM   2752 N  N   . ALA A 1 364 ? 37.08928  9.50827   -30.80881 1.000 14.90717  ?  364 ALA A N   1 
ATOM   2753 C  CA  . ALA A 1 364 ? 37.28181  8.98693   -32.16439 1.000 15.69898  ?  364 ALA A CA  1 
ATOM   2754 C  C   . ALA A 1 364 ? 36.24266  7.92850   -32.52732 1.000 17.82495  ?  364 ALA A C   1 
ATOM   2755 O  O   . ALA A 1 364 ? 36.56227  6.89586   -33.11815 1.000 16.22683  ?  364 ALA A O   1 
ATOM   2756 C  CB  . ALA A 1 364 ? 38.69669  8.43942   -32.34876 1.000 10.80283  ?  364 ALA A CB  1 
ATOM   2757 N  N   . GLU A 1 365 ? 34.98296  8.18849   -32.17770 1.000 16.07602  ?  365 GLU A N   1 
ATOM   2758 C  CA  . GLU A 1 365 ? 33.87245  7.33206   -32.58901 1.000 13.57046  ?  365 GLU A CA  1 
ATOM   2759 C  C   . GLU A 1 365 ? 33.40358  7.74334   -33.98807 1.000 18.55622  ?  365 GLU A C   1 
ATOM   2760 O  O   . GLU A 1 365 ? 32.25280  8.11356   -34.21754 1.000 19.06944  ?  365 GLU A O   1 
ATOM   2761 C  CB  . GLU A 1 365 ? 32.74518  7.41472   -31.56805 1.000 14.03700  ?  365 GLU A CB  1 
ATOM   2762 C  CG  . GLU A 1 365 ? 31.68459  6.33414   -31.70266 1.000 22.74976  ?  365 GLU A CG  1 
ATOM   2763 C  CD  . GLU A 1 365 ? 30.44900  6.63660   -30.88135 1.000 27.90391  ?  365 GLU A CD  1 
ATOM   2764 O  OE1 . GLU A 1 365 ? 30.39004  7.73429   -30.28841 1.000 29.26312  ?  365 GLU A OE1 1 
ATOM   2765 O  OE2 . GLU A 1 365 ? 29.53873  5.78200   -30.83046 1.000 22.61940  -1 365 GLU A OE2 1 
ATOM   2766 N  N   . THR A 1 366 ? 34.33606  7.67103   -34.93668 1.000 20.46645  ?  366 THR A N   1 
ATOM   2767 C  CA  . THR A 1 366 ? 34.13918  8.29262   -36.23729 1.000 19.37659  ?  366 THR A CA  1 
ATOM   2768 C  C   . THR A 1 366 ? 34.80532  7.46340   -37.32549 1.000 16.40288  ?  366 THR A C   1 
ATOM   2769 O  O   . THR A 1 366 ? 35.75378  6.71454   -37.07636 1.000 15.67986  ?  366 THR A O   1 
ATOM   2770 C  CB  . THR A 1 366 ? 34.69966  9.72050   -36.25317 1.000 18.12373  ?  366 THR A CB  1 
ATOM   2771 O  OG1 . THR A 1 366 ? 34.55619  10.28100  -37.56201 1.000 23.29814  ?  366 THR A OG1 1 
ATOM   2772 C  CG2 . THR A 1 366 ? 36.17342  9.71948   -35.86938 1.000 12.34776  ?  366 THR A CG2 1 
ATOM   2773 N  N   . ASN A 1 367 ? 34.29324  7.61725   -38.54476 1.000 13.50756  ?  367 ASN A N   1 
ATOM   2774 C  CA  . ASN A 1 367 ? 34.90726  7.05903   -39.74146 1.000 15.72493  ?  367 ASN A CA  1 
ATOM   2775 C  C   . ASN A 1 367 ? 35.85048  8.03912   -40.42747 1.000 26.30846  ?  367 ASN A C   1 
ATOM   2776 O  O   . ASN A 1 367 ? 36.36837  7.72874   -41.50537 1.000 38.68892  ?  367 ASN A O   1 
ATOM   2777 C  CB  . ASN A 1 367 ? 33.82713  6.61037   -40.73116 1.000 11.79795  ?  367 ASN A CB  1 
ATOM   2778 C  CG  . ASN A 1 367 ? 33.11301  5.35135   -40.28407 1.000 20.64042  ?  367 ASN A CG  1 
ATOM   2779 O  OD1 . ASN A 1 367 ? 33.73615  4.41799   -39.77751 1.000 23.09691  ?  367 ASN A OD1 1 
ATOM   2780 N  ND2 . ASN A 1 367 ? 31.79757  5.31856   -40.46886 1.000 19.19706  ?  367 ASN A ND2 1 
ATOM   2781 N  N   . TRP A 1 368 ? 36.07763  9.20873   -39.83755 1.000 20.87823  ?  368 TRP A N   1 
ATOM   2782 C  CA  . TRP A 1 368 ? 36.92554  10.22913  -40.43077 1.000 14.99439  ?  368 TRP A CA  1 
ATOM   2783 C  C   . TRP A 1 368 ? 38.38790  9.99840   -40.05977 1.000 21.09790  ?  368 TRP A C   1 
ATOM   2784 O  O   . TRP A 1 368 ? 38.72163  9.16417   -39.21520 1.000 23.61325  ?  368 TRP A O   1 
ATOM   2785 C  CB  . TRP A 1 368 ? 36.47677  11.62293  -39.98900 1.000 12.19698  ?  368 TRP A CB  1 
ATOM   2786 C  CG  . TRP A 1 368 ? 35.11705  11.99817  -40.48185 1.000 10.82144  ?  368 TRP A CG  1 
ATOM   2787 C  CD1 . TRP A 1 368 ? 33.99290  12.17965  -39.73141 1.000 10.80234  ?  368 TRP A CD1 1 
ATOM   2788 C  CD2 . TRP A 1 368 ? 34.73302  12.22836  -41.84127 1.000 11.40510  ?  368 TRP A CD2 1 
ATOM   2789 N  NE1 . TRP A 1 368 ? 32.93272  12.51129  -40.53825 1.000 10.33195  ?  368 TRP A NE1 1 
ATOM   2790 C  CE2 . TRP A 1 368 ? 33.36091  12.54773  -41.83896 1.000 10.91343  ?  368 TRP A CE2 1 
ATOM   2791 C  CE3 . TRP A 1 368 ? 35.41628  12.19573  -43.06059 1.000 18.00303  ?  368 TRP A CE3 1 
ATOM   2792 C  CZ2 . TRP A 1 368 ? 32.65958  12.83342  -43.00699 1.000 10.80417  ?  368 TRP A CZ2 1 
ATOM   2793 C  CZ3 . TRP A 1 368 ? 34.71762  12.47941  -44.21960 1.000 18.31509  ?  368 TRP A CZ3 1 
ATOM   2794 C  CH2 . TRP A 1 368 ? 33.35379  12.79450  -44.18399 1.000 13.67652  ?  368 TRP A CH2 1 
ATOM   2795 N  N   . GLN A 1 369 ? 39.26907  10.75213  -40.71570 1.000 18.40722  ?  369 GLN A N   1 
ATOM   2796 C  CA  . GLN A 1 369 ? 40.69994  10.67828  -40.45447 1.000 16.72514  ?  369 GLN A CA  1 
ATOM   2797 C  C   . GLN A 1 369 ? 41.28632  12.08127  -40.46716 1.000 16.84461  ?  369 GLN A C   1 
ATOM   2798 O  O   . GLN A 1 369 ? 41.00049  12.86456  -41.37701 1.000 20.54908  ?  369 GLN A O   1 
ATOM   2799 C  CB  . GLN A 1 369 ? 41.40788  9.79587   -41.48857 1.000 19.10201  ?  369 GLN A CB  1 
ATOM   2800 C  CG  . GLN A 1 369 ? 42.85297  9.47854   -41.14497 1.000 20.34367  ?  369 GLN A CG  1 
ATOM   2801 C  CD  . GLN A 1 369 ? 43.51193  8.59165   -42.17969 1.000 19.87967  ?  369 GLN A CD  1 
ATOM   2802 O  OE1 . GLN A 1 369 ? 42.87505  8.16506   -43.14299 1.000 19.54249  ?  369 GLN A OE1 1 
ATOM   2803 N  NE2 . GLN A 1 369 ? 44.79520  8.30848   -41.98659 1.000 20.59379  ?  369 GLN A NE2 1 
ATOM   2804 N  N   . GLU A 1 370 ? 42.10848  12.38621  -39.45916 1.000 20.66332  ?  370 GLU A N   1 
ATOM   2805 C  CA  . GLU A 1 370 ? 42.78052  13.68370  -39.33287 1.000 23.56698  ?  370 GLU A CA  1 
ATOM   2806 C  C   . GLU A 1 370 ? 41.78565  14.84355  -39.35542 1.000 27.77900  ?  370 GLU A C   1 
ATOM   2807 O  O   . GLU A 1 370 ? 42.00903  15.86670  -40.00629 1.000 26.26619  ?  370 GLU A O   1 
ATOM   2808 C  CB  . GLU A 1 370 ? 43.84770  13.86321  -40.41500 1.000 19.72636  ?  370 GLU A CB  1 
ATOM   2809 C  CG  . GLU A 1 370 ? 45.01428  12.89577  -40.30157 1.000 18.92224  ?  370 GLU A CG  1 
ATOM   2810 C  CD  . GLU A 1 370 ? 46.04873  13.10074  -41.39072 1.000 22.39550  ?  370 GLU A CD  1 
ATOM   2811 O  OE1 . GLU A 1 370 ? 45.90384  14.06225  -42.17528 1.000 26.25843  ?  370 GLU A OE1 1 
ATOM   2812 O  OE2 . GLU A 1 370 ? 47.00491  12.29938  -41.46384 1.000 21.38865  -1 370 GLU A OE2 1 
ATOM   2813 N  N   . THR A 1 371 ? 40.68204  14.68530  -38.63529 1.000 23.38425  ?  371 THR A N   1 
ATOM   2814 C  CA  . THR A 1 371 ? 39.66119  15.71432  -38.50367 1.000 19.90381  ?  371 THR A CA  1 
ATOM   2815 C  C   . THR A 1 371 ? 39.59346  16.18042  -37.05039 1.000 18.14579  ?  371 THR A C   1 
ATOM   2816 O  O   . THR A 1 371 ? 40.40000  15.78273  -36.20612 1.000 17.15085  ?  371 THR A O   1 
ATOM   2817 C  CB  . THR A 1 371 ? 38.30138  15.19911  -38.98078 1.000 24.35333  ?  371 THR A CB  1 
ATOM   2818 O  OG1 . THR A 1 371 ? 37.84532  14.16214  -38.10170 1.000 22.93346  ?  371 THR A OG1 1 
ATOM   2819 C  CG2 . THR A 1 371 ? 38.40432  14.65650  -40.39837 1.000 20.32192  ?  371 THR A CG2 1 
ATOM   2820 N  N   . GLU A 1 372 ? 38.61521  17.04176  -36.76831 1.000 24.53163  ?  372 GLU A N   1 
ATOM   2821 C  CA  . GLU A 1 372 ? 38.40527  17.51088  -35.40394 1.000 25.86084  ?  372 GLU A CA  1 
ATOM   2822 C  C   . GLU A 1 372 ? 37.92399  16.38983  -34.48976 1.000 24.89545  ?  372 GLU A C   1 
ATOM   2823 O  O   . GLU A 1 372 ? 38.17972  16.42462  -33.28026 1.000 24.10801  ?  372 GLU A O   1 
ATOM   2824 C  CB  . GLU A 1 372 ? 37.40241  18.66463  -35.40594 1.000 18.41615  ?  372 GLU A CB  1 
ATOM   2825 C  CG  . GLU A 1 372 ? 37.38155  19.48009  -34.13154 1.000 20.94949  ?  372 GLU A CG  1 
ATOM   2826 C  CD  . GLU A 1 372 ? 36.23955  20.47542  -34.09918 1.000 28.61949  ?  372 GLU A CD  1 
ATOM   2827 O  OE1 . GLU A 1 372 ? 35.46851  20.52655  -35.08038 1.000 28.71733  ?  372 GLU A OE1 1 
ATOM   2828 O  OE2 . GLU A 1 372 ? 36.11113  21.20394  -33.09235 1.000 36.03231  -1 372 GLU A OE2 1 
ATOM   2829 N  N   . VAL A 1 373 ? 37.23774  15.39131  -35.04539 1.000 20.11304  ?  373 VAL A N   1 
ATOM   2830 C  CA  . VAL A 1 373 ? 36.61696  14.35349  -34.22602 1.000 16.52232  ?  373 VAL A CA  1 
ATOM   2831 C  C   . VAL A 1 373 ? 37.66209  13.37371  -33.70755 1.000 18.82626  ?  373 VAL A C   1 
ATOM   2832 O  O   . VAL A 1 373 ? 37.80493  13.17125  -32.49642 1.000 16.48951  ?  373 VAL A O   1 
ATOM   2833 C  CB  . VAL A 1 373 ? 35.52034  13.62709  -35.02518 1.000 15.42276  ?  373 VAL A CB  1 
ATOM   2834 C  CG1 . VAL A 1 373 ? 34.73190  12.69852  -34.11893 1.000 16.40616  ?  373 VAL A CG1 1 
ATOM   2835 C  CG2 . VAL A 1 373 ? 34.60593  14.63214  -35.70375 1.000 19.49655  ?  373 VAL A CG2 1 
ATOM   2836 N  N   . ASP A 1 374 ? 38.40592  12.74531  -34.61987 1.000 19.01788  ?  374 ASP A N   1 
ATOM   2837 C  CA  . ASP A 1 374 ? 39.35759  11.71425  -34.22184 1.000 18.36584  ?  374 ASP A CA  1 
ATOM   2838 C  C   . ASP A 1 374 ? 40.59507  12.28509  -33.54151 1.000 19.48291  ?  374 ASP A C   1 
ATOM   2839 O  O   . ASP A 1 374 ? 41.29531  11.54683  -32.84010 1.000 25.28007  ?  374 ASP A O   1 
ATOM   2840 C  CB  . ASP A 1 374 ? 39.76187  10.86835  -35.43238 1.000 16.37134  ?  374 ASP A CB  1 
ATOM   2841 C  CG  . ASP A 1 374 ? 40.34497  11.69249  -36.56534 1.000 16.51831  ?  374 ASP A CG  1 
ATOM   2842 O  OD1 . ASP A 1 374 ? 40.39754  12.93385  -36.45989 1.000 19.86021  ?  374 ASP A OD1 1 
ATOM   2843 O  OD2 . ASP A 1 374 ? 40.75703  11.08649  -37.57301 1.000 18.08760  -1 374 ASP A OD2 1 
ATOM   2844 N  N   . TYR A 1 375 ? 40.88315  13.57283  -33.72644 1.000 19.47535  ?  375 TYR A N   1 
ATOM   2845 C  CA  . TYR A 1 375 ? 41.98747  14.18190  -32.99664 1.000 22.50249  ?  375 TYR A CA  1 
ATOM   2846 C  C   . TYR A 1 375 ? 41.64448  14.44255  -31.53810 1.000 25.50172  ?  375 TYR A C   1 
ATOM   2847 O  O   . TYR A 1 375 ? 42.52202  14.87609  -30.78254 1.000 28.23339  ?  375 TYR A O   1 
ATOM   2848 C  CB  . TYR A 1 375 ? 42.43223  15.47423  -33.68556 1.000 20.64358  ?  375 TYR A CB  1 
ATOM   2849 C  CG  . TYR A 1 375 ? 43.47279  15.24618  -34.76348 1.000 19.24871  ?  375 TYR A CG  1 
ATOM   2850 C  CD1 . TYR A 1 375 ? 44.44204  14.26116  -34.61976 1.000 17.19281  ?  375 TYR A CD1 1 
ATOM   2851 C  CD2 . TYR A 1 375 ? 43.48214  16.00681  -35.92565 1.000 20.44413  ?  375 TYR A CD2 1 
ATOM   2852 C  CE1 . TYR A 1 375 ? 45.39385  14.04416  -35.59889 1.000 15.01421  ?  375 TYR A CE1 1 
ATOM   2853 C  CE2 . TYR A 1 375 ? 44.43084  15.79521  -36.91095 1.000 15.62176  ?  375 TYR A CE2 1 
ATOM   2854 C  CZ  . TYR A 1 375 ? 45.38278  14.81293  -36.74102 1.000 12.25480  ?  375 TYR A CZ  1 
ATOM   2855 O  OH  . TYR A 1 375 ? 46.32770  14.59845  -37.71654 1.000 15.70551  ?  375 TYR A OH  1 
ATOM   2856 N  N   . ASN A 1 376 ? 40.39860  14.18319  -31.12693 1.000 20.16196  ?  376 ASN A N   1 
ATOM   2857 C  CA  . ASN A 1 376 ? 40.06272  14.18452  -29.70817 1.000 19.06061  ?  376 ASN A CA  1 
ATOM   2858 C  C   . ASN A 1 376 ? 40.83894  13.12407  -28.94150 1.000 18.60111  ?  376 ASN A C   1 
ATOM   2859 O  O   . ASN A 1 376 ? 40.89849  13.18620  -27.71011 1.000 20.45814  ?  376 ASN A O   1 
ATOM   2860 C  CB  . ASN A 1 376 ? 38.56142  13.95948  -29.50830 1.000 20.19458  ?  376 ASN A CB  1 
ATOM   2861 C  CG  . ASN A 1 376 ? 37.72584  15.13791  -29.96373 1.000 20.34954  ?  376 ASN A CG  1 
ATOM   2862 O  OD1 . ASN A 1 376 ? 38.21056  16.26602  -30.03279 1.000 26.67510  ?  376 ASN A OD1 1 
ATOM   2863 N  ND2 . ASN A 1 376 ? 36.45774  14.88277  -30.26826 1.000 14.46670  ?  376 ASN A ND2 1 
ATOM   2864 N  N   . LEU A 1 377 ? 41.41169  12.13977  -29.63912 1.000 19.63831  ?  377 LEU A N   1 
ATOM   2865 C  CA  . LEU A 1 377 ? 42.26555  11.15962  -28.97686 1.000 21.21637  ?  377 LEU A CA  1 
ATOM   2866 C  C   . LEU A 1 377 ? 43.47447  11.82641  -28.33858 1.000 20.85938  ?  377 LEU A C   1 
ATOM   2867 O  O   . LEU A 1 377 ? 43.87763  11.46517  -27.22627 1.000 24.66858  ?  377 LEU A O   1 
ATOM   2868 C  CB  . LEU A 1 377 ? 42.71685  10.09694  -29.97490 1.000 18.75360  ?  377 LEU A CB  1 
ATOM   2869 C  CG  . LEU A 1 377 ? 41.68193  9.05614   -30.38630 1.000 17.22791  ?  377 LEU A CG  1 
ATOM   2870 C  CD1 . LEU A 1 377 ? 42.19002  8.28935   -31.58729 1.000 24.33421  ?  377 LEU A CD1 1 
ATOM   2871 C  CD2 . LEU A 1 377 ? 41.39518  8.11455   -29.23025 1.000 13.70567  ?  377 LEU A CD2 1 
ATOM   2872 N  N   . ALA A 1 378 ? 44.07758  12.79116  -29.03636 1.000 18.23506  ?  378 ALA A N   1 
ATOM   2873 C  CA  . ALA A 1 378 ? 45.20052  13.51889  -28.45935 1.000 15.76749  ?  378 ALA A CA  1 
ATOM   2874 C  C   . ALA A 1 378 ? 44.77870  14.24815  -27.19268 1.000 20.99888  ?  378 ALA A C   1 
ATOM   2875 O  O   . ALA A 1 378 ? 45.49251  14.22087  -26.18401 1.000 22.37790  ?  378 ALA A O   1 
ATOM   2876 C  CB  . ALA A 1 378 ? 45.77301  14.49902  -29.48242 1.000 12.15348  ?  378 ALA A CB  1 
ATOM   2877 N  N   . ASP A 1 379 ? 43.60913  14.89042  -27.22128 1.000 21.04846  ?  379 ASP A N   1 
ATOM   2878 C  CA  . ASP A 1 379 ? 43.11480  15.58262  -26.03662 1.000 19.87598  ?  379 ASP A CA  1 
ATOM   2879 C  C   . ASP A 1 379 ? 42.85781  14.61063  -24.89362 1.000 26.28666  ?  379 ASP A C   1 
ATOM   2880 O  O   . ASP A 1 379 ? 43.20147  14.89276  -23.74069 1.000 26.60421  ?  379 ASP A O   1 
ATOM   2881 C  CB  . ASP A 1 379 ? 41.84474  16.35884  -26.37862 1.000 21.38278  ?  379 ASP A CB  1 
ATOM   2882 C  CG  . ASP A 1 379 ? 42.07947  17.40942  -27.43997 1.000 25.09453  ?  379 ASP A CG  1 
ATOM   2883 O  OD1 . ASP A 1 379 ? 43.19282  17.97109  -27.47000 1.000 20.52047  ?  379 ASP A OD1 1 
ATOM   2884 O  OD2 . ASP A 1 379 ? 41.15908  17.67006  -28.24374 1.000 27.45003  -1 379 ASP A OD2 1 
ATOM   2885 N  N   . ALA A 1 380 ? 42.25535  13.45917  -25.19433 1.000 21.47501  ?  380 ALA A N   1 
ATOM   2886 C  CA  . ALA A 1 380 ? 41.98312  12.47412  -24.15417 1.000 17.75191  ?  380 ALA A CA  1 
ATOM   2887 C  C   . ALA A 1 380 ? 43.27425  11.96398  -23.52942 1.000 23.20329  ?  380 ALA A C   1 
ATOM   2888 O  O   . ALA A 1 380 ? 43.37336  11.84260  -22.30316 1.000 28.74402  ?  380 ALA A O   1 
ATOM   2889 C  CB  . ALA A 1 380 ? 41.16867  11.31587  -24.72816 1.000 19.12797  ?  380 ALA A CB  1 
ATOM   2890 N  N   . LEU A 1 381 ? 44.28037  11.67195  -24.35694 1.000 25.14127  ?  381 LEU A N   1 
ATOM   2891 C  CA  . LEU A 1 381 ? 45.55547  11.19231  -23.83256 1.000 24.22252  ?  381 LEU A CA  1 
ATOM   2892 C  C   . LEU A 1 381 ? 46.25942  12.26445  -23.01013 1.000 25.58838  ?  381 LEU A C   1 
ATOM   2893 O  O   . LEU A 1 381 ? 46.84685  11.96457  -21.96370 1.000 26.78212  ?  381 LEU A O   1 
ATOM   2894 C  CB  . LEU A 1 381 ? 46.44981  10.71955  -24.97733 1.000 19.58036  ?  381 LEU A CB  1 
ATOM   2895 C  CG  . LEU A 1 381 ? 46.01394  9.41476   -25.64138 1.000 14.99726  ?  381 LEU A CG  1 
ATOM   2896 C  CD1 . LEU A 1 381 ? 46.96314  9.03409   -26.76631 1.000 12.68053  ?  381 LEU A CD1 1 
ATOM   2897 C  CD2 . LEU A 1 381 ? 45.93131  8.31092   -24.60202 1.000 15.11590  ?  381 LEU A CD2 1 
ATOM   2898 N  N   . LEU A 1 382 ? 46.21423  13.51877  -23.46673 1.000 19.73736  ?  382 LEU A N   1 
ATOM   2899 C  CA  . LEU A 1 382 ? 46.89181  14.59775  -22.75776 1.000 17.19488  ?  382 LEU A CA  1 
ATOM   2900 C  C   . LEU A 1 382 ? 46.16679  15.00442  -21.48334 1.000 20.72126  ?  382 LEU A C   1 
ATOM   2901 O  O   . LEU A 1 382 ? 46.80080  15.54427  -20.57063 1.000 22.88689  ?  382 LEU A O   1 
ATOM   2902 C  CB  . LEU A 1 382 ? 47.04956  15.80508  -23.67644 1.000 12.89755  ?  382 LEU A CB  1 
ATOM   2903 C  CG  . LEU A 1 382 ? 47.99163  15.59358  -24.85864 1.000 15.35443  ?  382 LEU A CG  1 
ATOM   2904 C  CD1 . LEU A 1 382 ? 47.73445  16.64802  -25.90709 1.000 17.64431  ?  382 LEU A CD1 1 
ATOM   2905 C  CD2 . LEU A 1 382 ? 49.44172  15.62380  -24.40561 1.000 18.39352  ?  382 LEU A CD2 1 
ATOM   2906 N  N   . LEU A 1 383 ? 44.86159  14.76521  -21.40034 1.000 21.65259  ?  383 LEU A N   1 
ATOM   2907 C  CA  . LEU A 1 383 ? 44.10391  15.01002  -20.18299 1.000 23.31318  ?  383 LEU A CA  1 
ATOM   2908 C  C   . LEU A 1 383 ? 44.10126  13.80363  -19.25362 1.000 25.36031  ?  383 LEU A C   1 
ATOM   2909 O  O   . LEU A 1 383 ? 43.30769  13.76657  -18.30681 1.000 24.22286  ?  383 LEU A O   1 
ATOM   2910 C  CB  . LEU A 1 383 ? 42.67006  15.42199  -20.52673 1.000 19.66904  ?  383 LEU A CB  1 
ATOM   2911 C  CG  . LEU A 1 383 ? 42.53990  16.74638  -21.28585 1.000 17.26691  ?  383 LEU A CG  1 
ATOM   2912 C  CD1 . LEU A 1 383 ? 41.10323  16.99253  -21.71101 1.000 29.97908  ?  383 LEU A CD1 1 
ATOM   2913 C  CD2 . LEU A 1 383 ? 43.05791  17.90738  -20.45393 1.000 18.77597  ?  383 LEU A CD2 1 
ATOM   2914 N  N   . ASN A 1 384 ? 44.96967  12.82153  -19.51246 1.000 28.02411  ?  384 ASN A N   1 
ATOM   2915 C  CA  . ASN A 1 384 ? 45.14813  11.65272  -18.64982 1.000 33.28160  ?  384 ASN A CA  1 
ATOM   2916 C  C   . ASN A 1 384 ? 43.84415  10.87541  -18.48431 1.000 28.92694  ?  384 ASN A C   1 
ATOM   2917 O  O   . ASN A 1 384 ? 43.42719  10.54663  -17.37257 1.000 36.51613  ?  384 ASN A O   1 
ATOM   2918 C  CB  . ASN A 1 384 ? 45.71635  12.05833  -17.28819 1.000 42.12326  ?  384 ASN A CB  1 
ATOM   2919 C  CG  . ASN A 1 384 ? 47.05627  12.75168  -17.39785 1.000 43.58185  ?  384 ASN A CG  1 
ATOM   2920 O  OD1 . ASN A 1 384 ? 47.86482  12.43647  -18.27190 1.000 45.54947  ?  384 ASN A OD1 1 
ATOM   2921 N  ND2 . ASN A 1 384 ? 47.29968  13.70492  -16.50719 1.000 43.39145  ?  384 ASN A ND2 1 
ATOM   2922 N  N   . THR A 1 385 ? 43.19393  10.58205  -19.60667 1.000 21.05667  ?  385 THR A N   1 
ATOM   2923 C  CA  . THR A 1 385 ? 41.93824  9.84909   -19.54839 1.000 28.19455  ?  385 THR A CA  1 
ATOM   2924 C  C   . THR A 1 385 ? 42.17043  8.45178   -18.98191 1.000 35.47771  ?  385 THR A C   1 
ATOM   2925 O  O   . THR A 1 385 ? 43.18791  7.80829   -19.25644 1.000 35.29343  ?  385 THR A O   1 
ATOM   2926 C  CB  . THR A 1 385 ? 41.29197  9.77605   -20.93724 1.000 25.76948  ?  385 THR A CB  1 
ATOM   2927 O  OG1 . THR A 1 385 ? 39.97734  9.21545   -20.82926 1.000 24.02106  ?  385 THR A OG1 1 
ATOM   2928 C  CG2 . THR A 1 385 ? 42.12602  8.93083   -21.89417 1.000 25.20126  ?  385 THR A CG2 1 
ATOM   2929 N  N   . THR A 1 386 ? 41.23630  8.00480   -18.14134 1.000 28.28470  ?  386 THR A N   1 
ATOM   2930 C  CA  . THR A 1 386 ? 41.33104  6.66736   -17.56641 1.000 22.91856  ?  386 THR A CA  1 
ATOM   2931 C  C   . THR A 1 386 ? 41.11438  5.60163   -18.63263 1.000 29.34669  ?  386 THR A C   1 
ATOM   2932 O  O   . THR A 1 386 ? 41.89172  4.64565   -18.74022 1.000 30.87740  ?  386 THR A O   1 
ATOM   2933 C  CB  . THR A 1 386 ? 40.31460  6.51255   -16.43469 1.000 29.35241  ?  386 THR A CB  1 
ATOM   2934 O  OG1 . THR A 1 386 ? 40.48580  7.57526   -15.48804 1.000 47.30885  ?  386 THR A OG1 1 
ATOM   2935 C  CG2 . THR A 1 386 ? 40.49813  5.17735   -15.72966 1.000 25.40814  ?  386 THR A CG2 1 
ATOM   2936 N  N   . ARG A 1 387 ? 40.05961  5.75319   -19.43067 1.000 33.53796  ?  387 ARG A N   1 
ATOM   2937 C  CA  . ARG A 1 387 ? 39.77564  4.86403   -20.54629 1.000 26.64628  ?  387 ARG A CA  1 
ATOM   2938 C  C   . ARG A 1 387 ? 39.21478  5.68820   -21.69469 1.000 23.09674  ?  387 ARG A C   1 
ATOM   2939 O  O   . ARG A 1 387 ? 38.76374  6.82141   -21.51119 1.000 21.58222  ?  387 ARG A O   1 
ATOM   2940 C  CB  . ARG A 1 387 ? 38.78621  3.75214   -20.16720 1.000 16.97369  ?  387 ARG A CB  1 
ATOM   2941 C  CG  . ARG A 1 387 ? 39.29105  2.78723   -19.10948 1.000 18.13691  ?  387 ARG A CG  1 
ATOM   2942 C  CD  . ARG A 1 387 ? 38.35061  1.60705   -18.96354 1.000 22.49700  ?  387 ARG A CD  1 
ATOM   2943 N  NE  . ARG A 1 387 ? 36.98052  2.03300   -18.70799 1.000 22.34231  ?  387 ARG A NE  1 
ATOM   2944 C  CZ  . ARG A 1 387 ? 36.43285  2.11775   -17.50381 1.000 17.44697  ?  387 ARG A CZ  1 
ATOM   2945 N  NH1 . ARG A 1 387 ? 37.11108  1.80413   -16.41205 1.000 16.47409  ?  387 ARG A NH1 1 
ATOM   2946 N  NH2 . ARG A 1 387 ? 35.17205  2.52544   -17.39286 1.000 18.36008  ?  387 ARG A NH2 1 
ATOM   2947 N  N   . VAL A 1 388 ? 39.24833  5.10489   -22.88840 1.000 18.67453  ?  388 VAL A N   1 
ATOM   2948 C  CA  . VAL A 1 388 ? 38.74498  5.74573   -24.09615 1.000 15.80235  ?  388 VAL A CA  1 
ATOM   2949 C  C   . VAL A 1 388 ? 37.58498  4.92028   -24.62844 1.000 17.43386  ?  388 VAL A C   1 
ATOM   2950 O  O   . VAL A 1 388 ? 37.71886  3.70716   -24.82458 1.000 21.46625  ?  388 VAL A O   1 
ATOM   2951 C  CB  . VAL A 1 388 ? 39.84461  5.89553   -25.16255 1.000 14.97017  ?  388 VAL A CB  1 
ATOM   2952 C  CG1 . VAL A 1 388 ? 39.22912  6.17420   -26.52437 1.000 13.69681  ?  388 VAL A CG1 1 
ATOM   2953 C  CG2 . VAL A 1 388 ? 40.80491  7.00622   -24.77372 1.000 19.19885  ?  388 VAL A CG2 1 
ATOM   2954 N  N   . GLY A 1 389 ? 36.44888  5.57712   -24.85494 1.000 19.43937  ?  389 GLY A N   1 
ATOM   2955 C  CA  . GLY A 1 389 ? 35.30167  4.90448   -25.43746 1.000 17.95329  ?  389 GLY A CA  1 
ATOM   2956 C  C   . GLY A 1 389 ? 35.47487  4.75330   -26.93592 1.000 19.18766  ?  389 GLY A C   1 
ATOM   2957 O  O   . GLY A 1 389 ? 35.80943  5.71622   -27.63446 1.000 18.96151  ?  389 GLY A O   1 
ATOM   2958 N  N   . HIS A 1 390 ? 35.27053  3.52773   -27.42571 1.000 25.86985  ?  390 HIS A N   1 
ATOM   2959 C  CA  . HIS A 1 390 ? 35.28830  3.18485   -28.84584 1.000 31.84618  ?  390 HIS A CA  1 
ATOM   2960 C  C   . HIS A 1 390 ? 36.68893  3.25079   -29.44509 1.000 29.61887  ?  390 HIS A C   1 
ATOM   2961 O  O   . HIS A 1 390 ? 37.31179  2.21033   -29.67463 1.000 29.24599  ?  390 HIS A O   1 
ATOM   2962 C  CB  . HIS A 1 390 ? 34.32782  4.08493   -29.62692 1.000 24.28957  ?  390 HIS A CB  1 
ATOM   2963 C  CG  . HIS A 1 390 ? 32.96141  4.16441   -29.02349 1.000 23.63910  ?  390 HIS A CG  1 
ATOM   2964 N  ND1 . HIS A 1 390 ? 32.06501  3.11890   -29.07248 1.000 29.48323  ?  390 HIS A ND1 1 
ATOM   2965 C  CD2 . HIS A 1 390 ? 32.34251  5.15931   -28.34541 1.000 28.66557  ?  390 HIS A CD2 1 
ATOM   2966 C  CE1 . HIS A 1 390 ? 30.94960  3.46880   -28.45735 1.000 35.55762  ?  390 HIS A CE1 1 
ATOM   2967 N  NE2 . HIS A 1 390 ? 31.09199  4.70223   -28.00672 1.000 36.23142  ?  390 HIS A NE2 1 
ATOM   2968 N  N   . GLY A 1 391 ? 37.19327  4.45244   -29.70667 1.000 21.00747  ?  391 GLY A N   1 
ATOM   2969 C  CA  . GLY A 1 391 ? 38.48207  4.57003   -30.37247 1.000 17.49732  ?  391 GLY A CA  1 
ATOM   2970 C  C   . GLY A 1 391 ? 38.48464  3.95322   -31.75365 1.000 15.81518  ?  391 GLY A C   1 
ATOM   2971 O  O   . GLY A 1 391 ? 39.44924  3.27615   -32.13140 1.000 10.71397  ?  391 GLY A O   1 
ATOM   2972 N  N   . PHE A 1 392 ? 37.41012  4.16702   -32.51682 1.000 16.42324  ?  392 PHE A N   1 
ATOM   2973 C  CA  . PHE A 1 392 ? 37.28311  3.54055   -33.82782 1.000 13.07461  ?  392 PHE A CA  1 
ATOM   2974 C  C   . PHE A 1 392 ? 38.34692  4.03905   -34.79619 1.000 11.40601  ?  392 PHE A C   1 
ATOM   2975 O  O   . PHE A 1 392 ? 38.74115  3.31099   -35.71345 1.000 10.38796  ?  392 PHE A O   1 
ATOM   2976 C  CB  . PHE A 1 392 ? 35.88400  3.79864   -34.38667 1.000 15.44213  ?  392 PHE A CB  1 
ATOM   2977 C  CG  . PHE A 1 392 ? 35.40500  2.74499   -35.34311 1.000 15.09719  ?  392 PHE A CG  1 
ATOM   2978 C  CD1 . PHE A 1 392 ? 35.02979  1.49420   -34.88257 1.000 13.10300  ?  392 PHE A CD1 1 
ATOM   2979 C  CD2 . PHE A 1 392 ? 35.31246  3.01022   -36.69947 1.000 17.21225  ?  392 PHE A CD2 1 
ATOM   2980 C  CE1 . PHE A 1 392 ? 34.58390  0.52355   -35.75735 1.000 14.61581  ?  392 PHE A CE1 1 
ATOM   2981 C  CE2 . PHE A 1 392 ? 34.86540  2.04386   -37.58041 1.000 14.78428  ?  392 PHE A CE2 1 
ATOM   2982 C  CZ  . PHE A 1 392 ? 34.50107  0.79878   -37.10833 1.000 18.47388  ?  392 PHE A CZ  1 
ATOM   2983 N  N   . ALA A 1 393 ? 38.81899  5.27018   -34.61579 1.000 16.50383  ?  393 ALA A N   1 
ATOM   2984 C  CA  . ALA A 1 393 ? 39.87453  5.83199   -35.44537 1.000 15.43940  ?  393 ALA A CA  1 
ATOM   2985 C  C   . ALA A 1 393 ? 41.23906  5.78012   -34.77097 1.000 16.68867  ?  393 ALA A C   1 
ATOM   2986 O  O   . ALA A 1 393 ? 42.19970  6.35096   -35.29706 1.000 18.13715  ?  393 ALA A O   1 
ATOM   2987 C  CB  . ALA A 1 393 ? 39.53411  7.27294   -35.82919 1.000 14.82893  ?  393 ALA A CB  1 
ATOM   2988 N  N   . LEU A 1 394 ? 41.34411  5.11312   -33.61768 1.000 17.29921  ?  394 LEU A N   1 
ATOM   2989 C  CA  . LEU A 1 394 ? 42.62442  5.03022   -32.92114 1.000 14.07393  ?  394 LEU A CA  1 
ATOM   2990 C  C   . LEU A 1 394 ? 43.66135  4.29031   -33.75365 1.000 16.56442  ?  394 LEU A C   1 
ATOM   2991 O  O   . LEU A 1 394 ? 44.82901  4.69414   -33.80588 1.000 20.93514  ?  394 LEU A O   1 
ATOM   2992 C  CB  . LEU A 1 394 ? 42.44387  4.34758   -31.56608 1.000 14.86601  ?  394 LEU A CB  1 
ATOM   2993 C  CG  . LEU A 1 394 ? 43.72695  4.09442   -30.77188 1.000 15.52935  ?  394 LEU A CG  1 
ATOM   2994 C  CD1 . LEU A 1 394 ? 44.40519  5.40847   -30.41562 1.000 15.84873  ?  394 LEU A CD1 1 
ATOM   2995 C  CD2 . LEU A 1 394 ? 43.43856  3.27655   -29.52349 1.000 11.31282  ?  394 LEU A CD2 1 
ATOM   2996 N  N   . ILE A 1 395 ? 43.25148  3.20474   -34.41445 1.000 16.78927  ?  395 ILE A N   1 
ATOM   2997 C  CA  . ILE A 1 395 ? 44.18181  2.41509   -35.21607 1.000 22.27947  ?  395 ILE A CA  1 
ATOM   2998 C  C   . ILE A 1 395 ? 44.76468  3.24688   -36.35260 1.000 17.85841  ?  395 ILE A C   1 
ATOM   2999 O  O   . ILE A 1 395 ? 45.89344  3.00153   -36.79755 1.000 14.49844  ?  395 ILE A O   1 
ATOM   3000 C  CB  . ILE A 1 395 ? 43.47839  1.14243   -35.73244 1.000 19.34230  ?  395 ILE A CB  1 
ATOM   3001 C  CG1 . ILE A 1 395 ? 44.47143  0.22138   -36.44321 1.000 18.68324  ?  395 ILE A CG1 1 
ATOM   3002 C  CG2 . ILE A 1 395 ? 42.31137  1.50044   -36.64567 1.000 16.91547  ?  395 ILE A CG2 1 
ATOM   3003 C  CD1 . ILE A 1 395 ? 43.85786  -1.07175  -36.92381 1.000 18.40641  ?  395 ILE A CD1 1 
ATOM   3004 N  N   . LYS A 1 396 ? 44.02210  4.24960   -36.82926 1.000 15.48509  ?  396 LYS A N   1 
ATOM   3005 C  CA  . LYS A 1 396 ? 44.50878  5.11570   -37.89648 1.000 16.91081  ?  396 LYS A CA  1 
ATOM   3006 C  C   . LYS A 1 396 ? 45.60974  6.06502   -37.44159 1.000 15.06831  ?  396 LYS A C   1 
ATOM   3007 O  O   . LYS A 1 396 ? 46.23878  6.70353   -38.29119 1.000 15.09458  ?  396 LYS A O   1 
ATOM   3008 C  CB  . LYS A 1 396 ? 43.35236  5.92469   -38.48766 1.000 16.22834  ?  396 LYS A CB  1 
ATOM   3009 C  CG  . LYS A 1 396 ? 42.35117  5.10025   -39.27827 1.000 14.23151  ?  396 LYS A CG  1 
ATOM   3010 C  CD  . LYS A 1 396 ? 41.26877  5.98149   -39.87769 1.000 14.64968  ?  396 LYS A CD  1 
ATOM   3011 C  CE  . LYS A 1 396 ? 40.28040  5.16704   -40.69519 1.000 17.93432  ?  396 LYS A CE  1 
ATOM   3012 N  NZ  . LYS A 1 396 ? 39.17825  6.01157   -41.23231 1.000 18.65332  ?  396 LYS A NZ  1 
ATOM   3013 N  N   . HIS A 1 397 ? 45.85134  6.18561   -36.13985 1.000 14.73662  ?  397 HIS A N   1 
ATOM   3014 C  CA  . HIS A 1 397 ? 46.88783  7.07443   -35.61392 1.000 16.43970  ?  397 HIS A CA  1 
ATOM   3015 C  C   . HIS A 1 397 ? 47.93902  6.25650   -34.87787 1.000 17.71649  ?  397 HIS A C   1 
ATOM   3016 O  O   . HIS A 1 397 ? 47.69198  5.79309   -33.75010 1.000 18.57948  ?  397 HIS A O   1 
ATOM   3017 C  CB  . HIS A 1 397 ? 46.27722  8.12886   -34.69513 1.000 14.82057  ?  397 HIS A CB  1 
ATOM   3018 C  CG  . HIS A 1 397 ? 45.28026  9.01418   -35.37611 1.000 16.32137  ?  397 HIS A CG  1 
ATOM   3019 N  ND1 . HIS A 1 397 ? 45.64539  9.98520   -36.28364 1.000 22.00674  ?  397 HIS A ND1 1 
ATOM   3020 C  CD2 . HIS A 1 397 ? 43.93054  9.07341   -35.28521 1.000 18.00183  ?  397 HIS A CD2 1 
ATOM   3021 C  CE1 . HIS A 1 397 ? 44.56404  10.60517  -36.72166 1.000 20.31188  ?  397 HIS A CE1 1 
ATOM   3022 N  NE2 . HIS A 1 397 ? 43.51020  10.07148  -36.13078 1.000 18.84472  ?  397 HIS A NE2 1 
ATOM   3023 N  N   . PRO A 1 398 ? 49.12064  6.05265   -35.46819 1.000 17.61984  ?  398 PRO A N   1 
ATOM   3024 C  CA  . PRO A 1 398 ? 50.10458  5.14722   -34.84160 1.000 22.48582  ?  398 PRO A CA  1 
ATOM   3025 C  C   . PRO A 1 398 ? 50.59655  5.61275   -33.48002 1.000 24.41869  ?  398 PRO A C   1 
ATOM   3026 O  O   . PRO A 1 398 ? 50.53459  4.84751   -32.50574 1.000 25.15267  ?  398 PRO A O   1 
ATOM   3027 C  CB  . PRO A 1 398 ? 51.23961  5.10539   -35.87722 1.000 20.30983  ?  398 PRO A CB  1 
ATOM   3028 C  CG  . PRO A 1 398 ? 50.61307  5.54679   -37.16391 1.000 19.58171  ?  398 PRO A CG  1 
ATOM   3029 C  CD  . PRO A 1 398 ? 49.57333  6.54716   -36.77770 1.000 16.66469  ?  398 PRO A CD  1 
ATOM   3030 N  N   . ARG A 1 399 ? 51.09877  6.84765   -33.38497 1.000 21.95374  ?  399 ARG A N   1 
ATOM   3031 C  CA  . ARG A 1 399 ? 51.64186  7.32134   -32.11602 1.000 24.76716  ?  399 ARG A CA  1 
ATOM   3032 C  C   . ARG A 1 399 ? 50.56620  7.40811   -31.04267 1.000 25.68256  ?  399 ARG A C   1 
ATOM   3033 O  O   . ARG A 1 399 ? 50.85320  7.17885   -29.86366 1.000 23.83743  ?  399 ARG A O   1 
ATOM   3034 C  CB  . ARG A 1 399 ? 52.32300  8.67870   -32.29689 1.000 28.75215  ?  399 ARG A CB  1 
ATOM   3035 C  CG  . ARG A 1 399 ? 52.96036  9.22772   -31.02206 1.000 32.27281  ?  399 ARG A CG  1 
ATOM   3036 C  CD  . ARG A 1 399 ? 54.11457  8.35199   -30.54009 1.000 36.32552  ?  399 ARG A CD  1 
ATOM   3037 N  NE  . ARG A 1 399 ? 54.62519  8.77807   -29.24077 1.000 43.91041  ?  399 ARG A NE  1 
ATOM   3038 C  CZ  . ARG A 1 399 ? 54.54786  8.05996   -28.12775 1.000 42.29828  ?  399 ARG A CZ  1 
ATOM   3039 N  NH1 . ARG A 1 399 ? 54.01648  6.84844   -28.12159 1.000 45.13376  ?  399 ARG A NH1 1 
ATOM   3040 N  NH2 . ARG A 1 399 ? 55.02243  8.56753   -26.99316 1.000 29.06955  ?  399 ARG A NH2 1 
ATOM   3041 N  N   . PHE A 1 400 ? 49.32793  7.73562   -31.42244 1.000 21.30854  ?  400 PHE A N   1 
ATOM   3042 C  CA  . PHE A 1 400 ? 48.24462  7.73830   -30.44365 1.000 18.84180  ?  400 PHE A CA  1 
ATOM   3043 C  C   . PHE A 1 400 ? 48.02251  6.34169   -29.87622 1.000 18.79454  ?  400 PHE A C   1 
ATOM   3044 O  O   . PHE A 1 400 ? 47.86523  6.17430   -28.66029 1.000 17.49297  ?  400 PHE A O   1 
ATOM   3045 C  CB  . PHE A 1 400 ? 46.95471  8.27147   -31.07146 1.000 18.56994  ?  400 PHE A CB  1 
ATOM   3046 C  CG  . PHE A 1 400 ? 47.00733  9.73066   -31.44493 1.000 17.78437  ?  400 PHE A CG  1 
ATOM   3047 C  CD1 . PHE A 1 400 ? 48.10566  10.51206  -31.12470 1.000 19.50216  ?  400 PHE A CD1 1 
ATOM   3048 C  CD2 . PHE A 1 400 ? 45.94443  10.32331  -32.10746 1.000 16.42145  ?  400 PHE A CD2 1 
ATOM   3049 C  CE1 . PHE A 1 400 ? 48.14750  11.85067  -31.47141 1.000 20.38189  ?  400 PHE A CE1 1 
ATOM   3050 C  CE2 . PHE A 1 400 ? 45.98091  11.66021  -32.45536 1.000 17.32189  ?  400 PHE A CE2 1 
ATOM   3051 C  CZ  . PHE A 1 400 ? 47.08362  12.42513  -32.13575 1.000 14.44625  ?  400 PHE A CZ  1 
ATOM   3052 N  N   . THR A 1 401 ? 48.02610  5.32467   -30.74310 1.000 20.39465  ?  401 THR A N   1 
ATOM   3053 C  CA  . THR A 1 401 ? 47.88919  3.94592   -30.28281 1.000 22.79638  ?  401 THR A CA  1 
ATOM   3054 C  C   . THR A 1 401 ? 49.03042  3.57042   -29.34723 1.000 22.85728  ?  401 THR A C   1 
ATOM   3055 O  O   . THR A 1 401 ? 48.80990  2.99340   -28.27328 1.000 24.35539  ?  401 THR A O   1 
ATOM   3056 C  CB  . THR A 1 401 ? 47.85433  2.99355   -31.48108 1.000 17.88163  ?  401 THR A CB  1 
ATOM   3057 O  OG1 . THR A 1 401 ? 46.93011  3.47875   -32.46098 1.000 14.05277  ?  401 THR A OG1 1 
ATOM   3058 C  CG2 . THR A 1 401 ? 47.43297  1.59899   -31.04543 1.000 21.20036  ?  401 THR A CG2 1 
ATOM   3059 N  N   . GLU A 1 402 ? 50.26277  3.90270   -29.74093 1.000 20.73517  ?  402 GLU A N   1 
ATOM   3060 C  CA  . GLU A 1 402 ? 51.42232  3.56507   -28.92234 1.000 24.71250  ?  402 GLU A CA  1 
ATOM   3061 C  C   . GLU A 1 402 ? 51.33728  4.22710   -27.55369 1.000 28.93824  ?  402 GLU A C   1 
ATOM   3062 O  O   . GLU A 1 402 ? 51.52912  3.57368   -26.52268 1.000 33.82377  ?  402 GLU A O   1 
ATOM   3063 C  CB  . GLU A 1 402 ? 52.70834  3.98047   -29.63812 1.000 31.10341  ?  402 GLU A CB  1 
ATOM   3064 C  CG  . GLU A 1 402 ? 52.93479  3.29947   -30.97736 1.000 32.80668  ?  402 GLU A CG  1 
ATOM   3065 C  CD  . GLU A 1 402 ? 54.17803  3.80772   -31.68413 1.000 34.30917  ?  402 GLU A CD  1 
ATOM   3066 O  OE1 . GLU A 1 402 ? 54.74637  4.82536   -31.23340 1.000 31.54737  ?  402 GLU A OE1 1 
ATOM   3067 O  OE2 . GLU A 1 402 ? 54.58850  3.18875   -32.68866 1.000 32.42867  -1 402 GLU A OE2 1 
ATOM   3068 N  N   . LEU A 1 403 ? 51.03851  5.52784   -27.52756 1.000 27.58266  ?  403 LEU A N   1 
ATOM   3069 C  CA  . LEU A 1 403 ? 50.98533  6.26300   -26.26929 1.000 28.88059  ?  403 LEU A CA  1 
ATOM   3070 C  C   . LEU A 1 403 ? 49.86204  5.75708   -25.37435 1.000 25.72304  ?  403 LEU A C   1 
ATOM   3071 O  O   . LEU A 1 403 ? 50.04127  5.63434   -24.15673 1.000 25.03651  ?  403 LEU A O   1 
ATOM   3072 C  CB  . LEU A 1 403 ? 50.82151  7.75682   -26.54709 1.000 21.26077  ?  403 LEU A CB  1 
ATOM   3073 C  CG  . LEU A 1 403 ? 50.76557  8.67074   -25.32446 1.000 18.09127  ?  403 LEU A CG  1 
ATOM   3074 C  CD1 . LEU A 1 403 ? 52.02169  8.50957   -24.48157 1.000 32.86824  ?  403 LEU A CD1 1 
ATOM   3075 C  CD2 . LEU A 1 403 ? 50.58590  10.11495  -25.75661 1.000 22.70698  ?  403 LEU A CD2 1 
ATOM   3076 N  N   . ALA A 1 404 ? 48.69467  5.46349   -25.95346 1.000 25.39160  ?  404 ALA A N   1 
ATOM   3077 C  CA  . ALA A 1 404 ? 47.58794  4.96308   -25.14794 1.000 20.31764  ?  404 ALA A CA  1 
ATOM   3078 C  C   . ALA A 1 404 ? 47.89996  3.58617   -24.57674 1.000 22.40167  ?  404 ALA A C   1 
ATOM   3079 O  O   . ALA A 1 404 ? 47.51527  3.27977   -23.44211 1.000 22.51445  ?  404 ALA A O   1 
ATOM   3080 C  CB  . ALA A 1 404 ? 46.30683  4.93333   -25.97793 1.000 17.43603  ?  404 ALA A CB  1 
ATOM   3081 N  N   . LYS A 1 405 ? 48.58910  2.73792   -25.34652 1.000 25.40647  ?  405 LYS A N   1 
ATOM   3082 C  CA  . LYS A 1 405 ? 49.00918  1.44710   -24.80877 1.000 28.22766  ?  405 LYS A CA  1 
ATOM   3083 C  C   . LYS A 1 405 ? 50.02725  1.61784   -23.68668 1.000 30.55268  ?  405 LYS A C   1 
ATOM   3084 O  O   . LYS A 1 405 ? 49.94124  0.94220   -22.65425 1.000 23.75711  ?  405 LYS A O   1 
ATOM   3085 C  CB  . LYS A 1 405 ? 49.58196  0.57233   -25.92294 1.000 26.58707  ?  405 LYS A CB  1 
ATOM   3086 C  CG  . LYS A 1 405 ? 49.94448  -0.83418  -25.47521 1.000 25.74836  ?  405 LYS A CG  1 
ATOM   3087 C  CD  . LYS A 1 405 ? 50.25631  -1.72531  -26.66446 1.000 35.09493  ?  405 LYS A CD  1 
ATOM   3088 C  CE  . LYS A 1 405 ? 50.41706  -3.17488  -26.24067 1.000 38.29313  ?  405 LYS A CE  1 
ATOM   3089 N  NZ  . LYS A 1 405 ? 50.54428  -4.07830  -27.41687 1.000 37.03017  ?  405 LYS A NZ  1 
ATOM   3090 N  N   . GLU A 1 406 ? 50.99742  2.51748   -23.87117 1.000 38.77641  ?  406 GLU A N   1 
ATOM   3091 C  CA  . GLU A 1 406 ? 52.03800  2.70859   -22.86404 1.000 35.77779  ?  406 GLU A CA  1 
ATOM   3092 C  C   . GLU A 1 406 ? 51.46346  3.26097   -21.56554 1.000 28.57164  ?  406 GLU A C   1 
ATOM   3093 O  O   . GLU A 1 406 ? 51.80493  2.78408   -20.47678 1.000 37.86548  ?  406 GLU A O   1 
ATOM   3094 C  CB  . GLU A 1 406 ? 53.12492  3.63756   -23.40278 1.000 33.32838  ?  406 GLU A CB  1 
ATOM   3095 C  CG  . GLU A 1 406 ? 53.85341  3.09934   -24.61905 1.000 38.82318  ?  406 GLU A CG  1 
ATOM   3096 C  CD  . GLU A 1 406 ? 54.36838  4.20677   -25.51770 1.000 40.75511  ?  406 GLU A CD  1 
ATOM   3097 O  OE1 . GLU A 1 406 ? 54.44457  5.36408   -25.05271 1.000 41.47079  ?  406 GLU A OE1 1 
ATOM   3098 O  OE2 . GLU A 1 406 ? 54.69123  3.92175   -26.68999 1.000 49.78861  -1 406 GLU A OE2 1 
ATOM   3099 N  N   . ASN A 1 407 ? 50.58800  4.26366   -21.65832 1.000 20.67435  ?  407 ASN A N   1 
ATOM   3100 C  CA  . ASN A 1 407 ? 50.01023  4.86895   -20.46554 1.000 20.72778  ?  407 ASN A CA  1 
ATOM   3101 C  C   . ASN A 1 407 ? 49.05415  3.93558   -19.73601 1.000 26.04766  ?  407 ASN A C   1 
ATOM   3102 O  O   . ASN A 1 407 ? 48.65230  4.24760   -18.60954 1.000 25.34658  ?  407 ASN A O   1 
ATOM   3103 C  CB  . ASN A 1 407 ? 49.28750  6.16855   -20.82950 1.000 18.66772  ?  407 ASN A CB  1 
ATOM   3104 C  CG  . ASN A 1 407 ? 50.24535  7.31097   -21.10900 1.000 18.71822  ?  407 ASN A CG  1 
ATOM   3105 O  OD1 . ASN A 1 407 ? 51.35734  7.34558   -20.58326 1.000 25.79100  ?  407 ASN A OD1 1 
ATOM   3106 N  ND2 . ASN A 1 407 ? 49.81396  8.25823   -21.93490 1.000 17.31148  ?  407 ASN A ND2 1 
ATOM   3107 N  N   . GLY A 1 408 ? 48.68343  2.81161   -20.34371 1.000 20.54011  ?  408 GLY A N   1 
ATOM   3108 C  CA  . GLY A 1 408 ? 47.73445  1.89497   -19.75359 1.000 23.38549  ?  408 GLY A CA  1 
ATOM   3109 C  C   . GLY A 1 408 ? 46.28142  2.23546   -19.98361 1.000 22.96598  ?  408 GLY A C   1 
ATOM   3110 O  O   . GLY A 1 408 ? 45.41886  1.68864   -19.28553 1.000 24.44444  ?  408 GLY A O   1 
ATOM   3111 N  N   . VAL A 1 409 ? 45.98143  3.12321   -20.92720 1.000 22.88445  ?  409 VAL A N   1 
ATOM   3112 C  CA  . VAL A 1 409 ? 44.60600  3.51535   -21.21800 1.000 26.31000  ?  409 VAL A CA  1 
ATOM   3113 C  C   . VAL A 1 409 ? 43.95909  2.39864   -22.03220 1.000 28.63785  ?  409 VAL A C   1 
ATOM   3114 O  O   . VAL A 1 409 ? 44.32862  2.16239   -23.18492 1.000 29.72852  ?  409 VAL A O   1 
ATOM   3115 C  CB  . VAL A 1 409 ? 44.54811  4.85378   -21.96469 1.000 19.15711  ?  409 VAL A CB  1 
ATOM   3116 C  CG1 . VAL A 1 409 ? 43.10075  5.29290   -22.17875 1.000 17.17190  ?  409 VAL A CG1 1 
ATOM   3117 C  CG2 . VAL A 1 409 ? 45.32920  5.91710   -21.21183 1.000 20.37197  ?  409 VAL A CG2 1 
ATOM   3118 N  N   . ALA A 1 410 ? 42.99765  1.70421   -21.43038 1.000 19.63572  ?  410 ALA A N   1 
ATOM   3119 C  CA  . ALA A 1 410 ? 42.25824  0.67621   -22.14246 1.000 16.29809  ?  410 ALA A CA  1 
ATOM   3120 C  C   . ALA A 1 410 ? 41.18219  1.30965   -23.01757 1.000 21.61630  ?  410 ALA A C   1 
ATOM   3121 O  O   . ALA A 1 410 ? 40.81284  2.47517   -22.85012 1.000 25.91880  ?  410 ALA A O   1 
ATOM   3122 C  CB  . ALA A 1 410 ? 41.62716  -0.31439  -21.16577 1.000 16.23447  ?  410 ALA A CB  1 
ATOM   3123 N  N   . VAL A 1 411 ? 40.67673  0.52191   -23.96222 1.000 16.89022  ?  411 VAL A N   1 
ATOM   3124 C  CA  . VAL A 1 411 ? 39.66903  0.97424   -24.91247 1.000 15.15888  ?  411 VAL A CA  1 
ATOM   3125 C  C   . VAL A 1 411 ? 38.38712  0.18994   -24.67320 1.000 16.12845  ?  411 VAL A C   1 
ATOM   3126 O  O   . VAL A 1 411 ? 38.40577  -1.04599  -24.63009 1.000 22.28314  ?  411 VAL A O   1 
ATOM   3127 C  CB  . VAL A 1 411 ? 40.14901  0.81542   -26.36551 1.000 16.19507  ?  411 VAL A CB  1 
ATOM   3128 C  CG1 . VAL A 1 411 ? 39.00104  1.04916   -27.32383 1.000 15.52712  ?  411 VAL A CG1 1 
ATOM   3129 C  CG2 . VAL A 1 411 ? 41.28477  1.78333   -26.65172 1.000 13.51781  ?  411 VAL A CG2 1 
ATOM   3130 N  N   . GLU A 1 412 ? 37.27917  0.91041   -24.51690 1.000 15.02756  ?  412 GLU A N   1 
ATOM   3131 C  CA  . GLU A 1 412 ? 35.96585  0.30686   -24.30220 1.000 17.66494  ?  412 GLU A CA  1 
ATOM   3132 C  C   . GLU A 1 412 ? 35.32714  0.06366   -25.66391 1.000 25.86600  ?  412 GLU A C   1 
ATOM   3133 O  O   . GLU A 1 412 ? 34.74853  0.97354   -26.26270 1.000 24.87611  ?  412 GLU A O   1 
ATOM   3134 C  CB  . GLU A 1 412 ? 35.09984  1.21042   -23.43181 1.000 12.09704  ?  412 GLU A CB  1 
ATOM   3135 C  CG  . GLU A 1 412 ? 35.67494  1.47980   -22.05170 1.000 13.99614  ?  412 GLU A CG  1 
ATOM   3136 C  CD  . GLU A 1 412 ? 35.13665  2.75649   -21.43357 1.000 16.59465  ?  412 GLU A CD  1 
ATOM   3137 O  OE1 . GLU A 1 412 ? 35.00223  3.76138   -22.16267 1.000 16.02318  ?  412 GLU A OE1 1 
ATOM   3138 O  OE2 . GLU A 1 412 ? 34.84638  2.75610   -20.21935 1.000 17.38176  -1 412 GLU A OE2 1 
ATOM   3139 N  N   . VAL A 1 413 ? 35.42723  -1.16803  -26.15566 1.000 25.13594  ?  413 VAL A N   1 
ATOM   3140 C  CA  . VAL A 1 413 ? 34.88652  -1.53760  -27.45731 1.000 21.98939  ?  413 VAL A CA  1 
ATOM   3141 C  C   . VAL A 1 413 ? 33.45757  -2.02789  -27.26999 1.000 15.89693  ?  413 VAL A C   1 
ATOM   3142 O  O   . VAL A 1 413 ? 33.20215  -2.93961  -26.47469 1.000 15.56521  ?  413 VAL A O   1 
ATOM   3143 C  CB  . VAL A 1 413 ? 35.75525  -2.61551  -28.12608 1.000 18.20746  ?  413 VAL A CB  1 
ATOM   3144 C  CG1 . VAL A 1 413 ? 35.32755  -2.82222  -29.57084 1.000 22.25848  ?  413 VAL A CG1 1 
ATOM   3145 C  CG2 . VAL A 1 413 ? 37.22886  -2.24598  -28.03465 1.000 12.64764  ?  413 VAL A CG2 1 
ATOM   3146 N  N   . ASN A 1 414 ? 32.52285  -1.42172  -28.00269 1.000 15.61508  ?  414 ASN A N   1 
ATOM   3147 C  CA  . ASN A 1 414 ? 31.10944  -1.79549  -27.97471 1.000 18.64346  ?  414 ASN A CA  1 
ATOM   3148 C  C   . ASN A 1 414 ? 30.72234  -2.21036  -29.38766 1.000 27.62860  ?  414 ASN A C   1 
ATOM   3149 O  O   . ASN A 1 414 ? 30.25186  -1.38009  -30.18081 1.000 30.04723  ?  414 ASN A O   1 
ATOM   3150 C  CB  . ASN A 1 414 ? 30.24223  -0.64264  -27.47304 1.000 16.72446  ?  414 ASN A CB  1 
ATOM   3151 C  CG  . ASN A 1 414 ? 30.72863  -0.08005  -26.15066 1.000 18.38680  ?  414 ASN A CG  1 
ATOM   3152 O  OD1 . ASN A 1 414 ? 30.33729  -0.54781  -25.08334 1.000 19.72203  ?  414 ASN A OD1 1 
ATOM   3153 N  ND2 . ASN A 1 414 ? 31.58678  0.93092   -26.21650 1.000 18.80831  ?  414 ASN A ND2 1 
ATOM   3154 N  N   . PRO A 1 415 ? 30.89304  -3.48850  -29.74128 1.000 24.22743  ?  415 PRO A N   1 
ATOM   3155 C  CA  . PRO A 1 415 ? 30.75298  -3.88053  -31.15857 1.000 18.79470  ?  415 PRO A CA  1 
ATOM   3156 C  C   . PRO A 1 415 ? 29.36216  -3.65440  -31.72846 1.000 21.39206  ?  415 PRO A C   1 
ATOM   3157 O  O   . PRO A 1 415 ? 29.22640  -3.08708  -32.82223 1.000 20.90528  ?  415 PRO A O   1 
ATOM   3158 C  CB  . PRO A 1 415 ? 31.13029  -5.37014  -31.14013 1.000 20.64800  ?  415 PRO A CB  1 
ATOM   3159 C  CG  . PRO A 1 415 ? 31.89462  -5.56825  -29.86334 1.000 20.52259  ?  415 PRO A CG  1 
ATOM   3160 C  CD  . PRO A 1 415 ? 31.28631  -4.61944  -28.88681 1.000 18.73933  ?  415 PRO A CD  1 
ATOM   3161 N  N   . ILE A 1 416 ? 28.31990  -4.09257  -31.01873 1.000 23.93590  ?  416 ILE A N   1 
ATOM   3162 C  CA  . ILE A 1 416 ? 26.95701  -3.92774  -31.51794 1.000 25.25437  ?  416 ILE A CA  1 
ATOM   3163 C  C   . ILE A 1 416 ? 26.61126  -2.44930  -31.64019 1.000 26.74399  ?  416 ILE A C   1 
ATOM   3164 O  O   . ILE A 1 416 ? 25.95973  -2.02309  -32.60383 1.000 22.26113  ?  416 ILE A O   1 
ATOM   3165 C  CB  . ILE A 1 416 ? 25.96383  -4.67270  -30.60722 1.000 18.48868  ?  416 ILE A CB  1 
ATOM   3166 C  CG1 . ILE A 1 416 ? 26.41731  -6.11878  -30.40321 1.000 19.84736  ?  416 ILE A CG1 1 
ATOM   3167 C  CG2 . ILE A 1 416 ? 24.56397  -4.63359  -31.19857 1.000 24.23029  ?  416 ILE A CG2 1 
ATOM   3168 C  CD1 . ILE A 1 416 ? 25.46747  -6.94630  -29.56658 1.000 28.40869  ?  416 ILE A CD1 1 
ATOM   3169 N  N   . SER A 1 417 ? 27.04057  -1.64543  -30.66400 1.000 24.39713  ?  417 SER A N   1 
ATOM   3170 C  CA  . SER A 1 417 ? 26.82246  -0.20530  -30.73695 1.000 23.20343  ?  417 SER A CA  1 
ATOM   3171 C  C   . SER A 1 417 ? 27.51723  0.39473   -31.95196 1.000 17.69211  ?  417 SER A C   1 
ATOM   3172 O  O   . SER A 1 417 ? 26.94680  1.24314   -32.64653 1.000 14.43257  ?  417 SER A O   1 
ATOM   3173 C  CB  . SER A 1 417 ? 27.31343  0.46244   -29.45207 1.000 24.13430  ?  417 SER A CB  1 
ATOM   3174 O  OG  . SER A 1 417 ? 27.26835  1.87465   -29.55783 1.000 24.75581  ?  417 SER A OG  1 
ATOM   3175 N  N   . ASN A 1 418 ? 28.74983  -0.03762  -32.22749 1.000 19.32279  ?  418 ASN A N   1 
ATOM   3176 C  CA  . ASN A 1 418 ? 29.47998  0.49559   -33.37194 1.000 19.50853  ?  418 ASN A CA  1 
ATOM   3177 C  C   . ASN A 1 418 ? 28.86550  0.05046   -34.69206 1.000 19.39868  ?  418 ASN A C   1 
ATOM   3178 O  O   . ASN A 1 418 ? 28.99456  0.75485   -35.69964 1.000 16.00703  ?  418 ASN A O   1 
ATOM   3179 C  CB  . ASN A 1 418 ? 30.94923  0.08065   -33.30019 1.000 15.66448  ?  418 ASN A CB  1 
ATOM   3180 C  CG  . ASN A 1 418 ? 31.62578  0.56147   -32.03266 1.000 18.17798  ?  418 ASN A CG  1 
ATOM   3181 O  OD1 . ASN A 1 418 ? 32.49459  -0.11448  -31.48239 1.000 21.01559  ?  418 ASN A OD1 1 
ATOM   3182 N  ND2 . ASN A 1 418 ? 31.21769  1.73038   -31.55310 1.000 15.79548  ?  418 ASN A ND2 1 
ATOM   3183 N  N   . GLN A 1 419 ? 28.20287  -1.10811  -34.71466 1.000 23.78190  ?  419 GLN A N   1 
ATOM   3184 C  CA  . GLN A 1 419 ? 27.53835  -1.53641  -35.94135 1.000 18.96923  ?  419 GLN A CA  1 
ATOM   3185 C  C   . GLN A 1 419 ? 26.24238  -0.76936  -36.16867 1.000 15.69851  ?  419 GLN A C   1 
ATOM   3186 O  O   . GLN A 1 419 ? 26.01333  -0.23125  -37.25752 1.000 13.13744  ?  419 GLN A O   1 
ATOM   3187 C  CB  . GLN A 1 419 ? 27.25433  -3.03825  -35.90900 1.000 19.24166  ?  419 GLN A CB  1 
ATOM   3188 C  CG  . GLN A 1 419 ? 26.43813  -3.50803  -37.10845 1.000 18.19065  ?  419 GLN A CG  1 
ATOM   3189 C  CD  . GLN A 1 419 ? 26.05190  -4.97239  -37.03496 1.000 18.26742  ?  419 GLN A CD  1 
ATOM   3190 O  OE1 . GLN A 1 419 ? 25.36670  -5.40366  -36.10665 1.000 17.30881  ?  419 GLN A OE1 1 
ATOM   3191 N  NE2 . GLN A 1 419 ? 26.48752  -5.74570  -38.02169 1.000 17.42916  ?  419 GLN A NE2 1 
ATOM   3192 N  N   . ILE A 1 420 ? 25.37956  -0.71578  -35.15278 1.000 21.49688  ?  420 ILE A N   1 
ATOM   3193 C  CA  . ILE A 1 420 ? 24.07528  -0.08482  -35.32917 1.000 25.25779  ?  420 ILE A CA  1 
ATOM   3194 C  C   . ILE A 1 420 ? 24.22610  1.41393   -35.55765 1.000 20.75914  ?  420 ILE A C   1 
ATOM   3195 O  O   . ILE A 1 420 ? 23.59927  1.98240   -36.45862 1.000 26.70092  ?  420 ILE A O   1 
ATOM   3196 C  CB  . ILE A 1 420 ? 23.16554  -0.38986  -34.12549 1.000 20.28782  ?  420 ILE A CB  1 
ATOM   3197 C  CG1 . ILE A 1 420 ? 22.98524  -1.90069  -33.97502 1.000 18.97201  ?  420 ILE A CG1 1 
ATOM   3198 C  CG2 . ILE A 1 420 ? 21.81552  0.29092   -34.29055 1.000 13.67741  ?  420 ILE A CG2 1 
ATOM   3199 C  CD1 . ILE A 1 420 ? 22.03029  -2.29536  -32.88094 1.000 17.54186  ?  420 ILE A CD1 1 
ATOM   3200 N  N   . LEU A 1 421 ? 25.07492  2.07370   -34.77111 1.000 18.43066  ?  421 LEU A N   1 
ATOM   3201 C  CA  . LEU A 1 421 ? 25.20175  3.52310   -34.82540 1.000 17.00721  ?  421 LEU A CA  1 
ATOM   3202 C  C   . LEU A 1 421 ? 26.04238  4.01114   -36.00413 1.000 16.56015  ?  421 LEU A C   1 
ATOM   3203 O  O   . LEU A 1 421 ? 26.47262  5.16935   -35.99881 1.000 23.82215  ?  421 LEU A O   1 
ATOM   3204 C  CB  . LEU A 1 421 ? 25.77003  4.05373   -33.50763 1.000 18.93859  ?  421 LEU A CB  1 
ATOM   3205 C  CG  . LEU A 1 421 ? 24.83582  3.88870   -32.30525 1.000 11.45572  ?  421 LEU A CG  1 
ATOM   3206 C  CD1 . LEU A 1 421 ? 25.42931  4.52125   -31.05872 1.000 14.06271  ?  421 LEU A CD1 1 
ATOM   3207 C  CD2 . LEU A 1 421 ? 23.46607  4.47711   -32.60743 1.000 15.27730  ?  421 LEU A CD2 1 
ATOM   3208 N  N   . GLY A 1 422 ? 26.30095  3.16215   -36.99534 1.000 14.02971  ?  422 GLY A N   1 
ATOM   3209 C  CA  . GLY A 1 422 ? 26.77842  3.62038   -38.28361 1.000 19.33331  ?  422 GLY A CA  1 
ATOM   3210 C  C   . GLY A 1 422 ? 28.27508  3.63105   -38.49790 1.000 18.03967  ?  422 GLY A C   1 
ATOM   3211 O  O   . GLY A 1 422 ? 28.72730  4.16020   -39.52053 1.000 21.23395  ?  422 GLY A O   1 
ATOM   3212 N  N   . LEU A 1 423 ? 29.06367  3.07018   -37.58117 1.000 14.33721  ?  423 LEU A N   1 
ATOM   3213 C  CA  . LEU A 1 423 ? 30.50660  3.05690   -37.79720 1.000 15.44525  ?  423 LEU A CA  1 
ATOM   3214 C  C   . LEU A 1 423 ? 30.93410  1.90470   -38.69877 1.000 20.51271  ?  423 LEU A C   1 
ATOM   3215 O  O   . LEU A 1 423 ? 31.79513  2.08331   -39.56704 1.000 19.68679  ?  423 LEU A O   1 
ATOM   3216 C  CB  . LEU A 1 423 ? 31.24648  2.98897   -36.46161 1.000 17.75595  ?  423 LEU A CB  1 
ATOM   3217 C  CG  . LEU A 1 423 ? 31.33851  4.29893   -35.67841 1.000 19.19479  ?  423 LEU A CG  1 
ATOM   3218 C  CD1 . LEU A 1 423 ? 32.28687  4.14431   -34.50465 1.000 15.15458  ?  423 LEU A CD1 1 
ATOM   3219 C  CD2 . LEU A 1 423 ? 31.77846  5.44189   -36.58052 1.000 17.44476  ?  423 LEU A CD2 1 
ATOM   3220 N  N   . VAL A 1 424 ? 30.35127  0.71878   -38.51050 1.000 22.79007  ?  424 VAL A N   1 
ATOM   3221 C  CA  . VAL A 1 424 ? 30.71691  -0.46257  -39.28072 1.000 17.82480  ?  424 VAL A CA  1 
ATOM   3222 C  C   . VAL A 1 424 ? 29.44925  -1.21101  -39.67363 1.000 19.34616  ?  424 VAL A C   1 
ATOM   3223 O  O   . VAL A 1 424 ? 28.39181  -1.05775  -39.05865 1.000 20.14510  ?  424 VAL A O   1 
ATOM   3224 C  CB  . VAL A 1 424 ? 31.67689  -1.38716  -38.49402 1.000 16.60798  ?  424 VAL A CB  1 
ATOM   3225 C  CG1 . VAL A 1 424 ? 30.90706  -2.24557  -37.49566 1.000 16.76140  ?  424 VAL A CG1 1 
ATOM   3226 C  CG2 . VAL A 1 424 ? 32.50899  -2.24115  -39.44262 1.000 16.87750  ?  424 VAL A CG2 1 
ATOM   3227 N  N   . ARG A 1 425 ? 29.56500  -2.02329  -40.72373 1.000 22.44854  ?  425 ARG A N   1 
ATOM   3228 C  CA  . ARG A 1 425 ? 28.46290  -2.85533  -41.19199 1.000 26.42334  ?  425 ARG A CA  1 
ATOM   3229 C  C   . ARG A 1 425 ? 28.77066  -4.33929  -41.07387 1.000 31.46898  ?  425 ARG A C   1 
ATOM   3230 O  O   . ARG A 1 425 ? 27.95076  -5.09817  -40.54230 1.000 30.29978  ?  425 ARG A O   1 
ATOM   3231 C  CB  . ARG A 1 425 ? 28.11272  -2.49607  -42.64373 1.000 31.64065  ?  425 ARG A CB  1 
ATOM   3232 C  CG  . ARG A 1 425 ? 26.62246  -2.35755  -42.90309 1.000 46.25970  ?  425 ARG A CG  1 
ATOM   3233 C  CD  . ARG A 1 425 ? 26.37236  -1.83318  -44.30237 1.000 51.58256  ?  425 ARG A CD  1 
ATOM   3234 N  NE  . ARG A 1 425 ? 24.96203  -1.57843  -44.56958 1.000 62.96057  ?  425 ARG A NE  1 
ATOM   3235 C  CZ  . ARG A 1 425 ? 24.37125  -0.40085  -44.41735 1.000 67.98165  ?  425 ARG A CZ  1 
ATOM   3236 N  NH1 . ARG A 1 425 ? 25.03782  0.65632   -43.98289 1.000 66.29693  ?  425 ARG A NH1 1 
ATOM   3237 N  NH2 . ARG A 1 425 ? 23.07978  -0.28013  -44.71103 1.000 57.82095  ?  425 ARG A NH2 1 
ATOM   3238 N  N   . ASP A 1 426 ? 29.92816  -4.77879  -41.56062 1.000 29.96389  ?  426 ASP A N   1 
ATOM   3239 C  CA  . ASP A 1 426 ? 30.41786  -6.12741  -41.30822 1.000 19.10637  ?  426 ASP A CA  1 
ATOM   3240 C  C   . ASP A 1 426 ? 31.28776  -6.07583  -40.05840 1.000 19.05536  ?  426 ASP A C   1 
ATOM   3241 O  O   . ASP A 1 426 ? 32.32845  -5.41042  -40.05035 1.000 22.57906  ?  426 ASP A O   1 
ATOM   3242 C  CB  . ASP A 1 426 ? 31.20191  -6.65763  -42.50983 1.000 19.48198  ?  426 ASP A CB  1 
ATOM   3243 C  CG  . ASP A 1 426 ? 31.48073  -8.15354  -42.42276 1.000 24.86499  ?  426 ASP A CG  1 
ATOM   3244 O  OD1 . ASP A 1 426 ? 31.77305  -8.65296  -41.31605 1.000 21.14133  ?  426 ASP A OD1 1 
ATOM   3245 O  OD2 . ASP A 1 426 ? 31.40965  -8.83442  -43.46859 1.000 29.44878  -1 426 ASP A OD2 1 
ATOM   3246 N  N   . VAL A 1 427 ? 30.85442  -6.76651  -39.00101 1.000 17.45497  ?  427 VAL A N   1 
ATOM   3247 C  CA  . VAL A 1 427 ? 31.54333  -6.66987  -37.71686 1.000 14.00897  ?  427 VAL A CA  1 
ATOM   3248 C  C   . VAL A 1 427 ? 32.96332  -7.21231  -37.81217 1.000 14.43804  ?  427 VAL A C   1 
ATOM   3249 O  O   . VAL A 1 427 ? 33.84235  -6.80766  -37.04163 1.000 16.39374  ?  427 VAL A O   1 
ATOM   3250 C  CB  . VAL A 1 427 ? 30.73094  -7.38872  -36.62337 1.000 15.04440  ?  427 VAL A CB  1 
ATOM   3251 C  CG1 . VAL A 1 427 ? 31.25698  -7.02006  -35.24503 1.000 19.77974  ?  427 VAL A CG1 1 
ATOM   3252 C  CG2 . VAL A 1 427 ? 29.25912  -7.03597  -36.74778 1.000 12.61332  ?  427 VAL A CG2 1 
ATOM   3253 N  N   . ARG A 1 428 ? 33.21889  -8.12713  -38.75120 1.000 15.11271  ?  428 ARG A N   1 
ATOM   3254 C  CA  . ARG A 1 428 ? 34.58120  -8.60718  -38.95500 1.000 15.86018  ?  428 ARG A CA  1 
ATOM   3255 C  C   . ARG A 1 428 ? 35.49758  -7.51706  -39.49288 1.000 17.56128  ?  428 ARG A C   1 
ATOM   3256 O  O   . ARG A 1 428 ? 36.72241  -7.64677  -39.39110 1.000 20.52421  ?  428 ARG A O   1 
ATOM   3257 C  CB  . ARG A 1 428 ? 34.58932  -9.80761  -39.90210 1.000 18.16613  ?  428 ARG A CB  1 
ATOM   3258 C  CG  . ARG A 1 428 ? 33.70315  -10.95379 -39.45093 1.000 17.57550  ?  428 ARG A CG  1 
ATOM   3259 C  CD  . ARG A 1 428 ? 34.04398  -12.23982 -40.18493 1.000 20.60555  ?  428 ARG A CD  1 
ATOM   3260 N  NE  . ARG A 1 428 ? 34.05227  -12.06961 -41.63340 1.000 27.73050  ?  428 ARG A NE  1 
ATOM   3261 C  CZ  . ARG A 1 428 ? 32.98176  -12.18200 -42.40820 1.000 26.56055  ?  428 ARG A CZ  1 
ATOM   3262 N  NH1 . ARG A 1 428 ? 31.78674  -12.43671 -41.90342 1.000 32.71955  ?  428 ARG A NH1 1 
ATOM   3263 N  NH2 . ARG A 1 428 ? 33.11368  -12.03803 -43.72334 1.000 24.76838  ?  428 ARG A NH2 1 
ATOM   3264 N  N   . ASN A 1 429 ? 34.93272  -6.45354  -40.06481 1.000 16.64074  ?  429 ASN A N   1 
ATOM   3265 C  CA  . ASN A 1 429 ? 35.68959  -5.29395  -40.51229 1.000 17.69576  ?  429 ASN A CA  1 
ATOM   3266 C  C   . ASN A 1 429 ? 35.80783  -4.22115  -39.43633 1.000 20.40443  ?  429 ASN A C   1 
ATOM   3267 O  O   . ASN A 1 429 ? 36.03562  -3.05120  -39.76494 1.000 23.39874  ?  429 ASN A O   1 
ATOM   3268 C  CB  . ASN A 1 429 ? 35.05425  -4.70025  -41.77177 1.000 13.38968  ?  429 ASN A CB  1 
ATOM   3269 C  CG  . ASN A 1 429 ? 35.60762  -5.30530  -43.04474 1.000 14.70885  ?  429 ASN A CG  1 
ATOM   3270 O  OD1 . ASN A 1 429 ? 36.35838  -6.27942  -43.00847 1.000 19.72286  ?  429 ASN A OD1 1 
ATOM   3271 N  ND2 . ASN A 1 429 ? 35.23772  -4.72884  -44.18146 1.000 16.67143  ?  429 ASN A ND2 1 
ATOM   3272 N  N   . HIS A 1 430 ? 35.65152  -4.58945  -38.16690 1.000 21.53204  ?  430 HIS A N   1 
ATOM   3273 C  CA  . HIS A 1 430 ? 35.79518  -3.62752  -37.08494 1.000 17.12797  ?  430 HIS A CA  1 
ATOM   3274 C  C   . HIS A 1 430 ? 37.23287  -3.12520  -37.01465 1.000 19.13486  ?  430 HIS A C   1 
ATOM   3275 O  O   . HIS A 1 430 ? 38.18596  -3.85741  -37.29544 1.000 18.70508  ?  430 HIS A O   1 
ATOM   3276 C  CB  . HIS A 1 430 ? 35.38797  -4.25379  -35.75083 1.000 20.86148  ?  430 HIS A CB  1 
ATOM   3277 C  CG  . HIS A 1 430 ? 35.17859  -3.25692  -34.65300 1.000 23.75111  ?  430 HIS A CG  1 
ATOM   3278 N  ND1 . HIS A 1 430 ? 33.95223  -2.68405  -34.39242 1.000 21.70466  ?  430 HIS A ND1 1 
ATOM   3279 C  CD2 . HIS A 1 430 ? 36.03934  -2.72861  -33.75079 1.000 19.36217  ?  430 HIS A CD2 1 
ATOM   3280 C  CE1 . HIS A 1 430 ? 34.06572  -1.84843  -33.37572 1.000 15.34048  ?  430 HIS A CE1 1 
ATOM   3281 N  NE2 . HIS A 1 430 ? 35.32209  -1.85614  -32.96859 1.000 15.91555  ?  430 HIS A NE2 1 
ATOM   3282 N  N   . ALA A 1 431 ? 37.38078  -1.85438  -36.63251 1.000 16.92875  ?  431 ALA A N   1 
ATOM   3283 C  CA  . ALA A 1 431 ? 38.68594  -1.20578  -36.70225 1.000 16.31513  ?  431 ALA A CA  1 
ATOM   3284 C  C   . ALA A 1 431 ? 39.64137  -1.70763  -35.62623 1.000 20.33738  ?  431 ALA A C   1 
ATOM   3285 O  O   . ALA A 1 431 ? 40.86206  -1.64921  -35.81166 1.000 20.96790  ?  431 ALA A O   1 
ATOM   3286 C  CB  . ALA A 1 431 ? 38.52131  0.30843   -36.59775 1.000 12.21025  ?  431 ALA A CB  1 
ATOM   3287 N  N   . LEU A 1 432 ? 39.11964  -2.19907  -34.50642 1.000 17.24867  ?  432 LEU A N   1 
ATOM   3288 C  CA  . LEU A 1 432 ? 39.95333  -2.60116  -33.38163 1.000 13.81832  ?  432 LEU A CA  1 
ATOM   3289 C  C   . LEU A 1 432 ? 40.35531  -4.06977  -33.41917 1.000 15.16674  ?  432 LEU A C   1 
ATOM   3290 O  O   . LEU A 1 432 ? 41.00710  -4.53786  -32.48099 1.000 16.12149  ?  432 LEU A O   1 
ATOM   3291 C  CB  . LEU A 1 432 ? 39.23513  -2.29594  -32.06595 1.000 15.14250  ?  432 LEU A CB  1 
ATOM   3292 C  CG  . LEU A 1 432 ? 39.08729  -0.80520  -31.76333 1.000 21.83986  ?  432 LEU A CG  1 
ATOM   3293 C  CD1 . LEU A 1 432 ? 37.72633  -0.52285  -31.16295 1.000 23.86182  ?  432 LEU A CD1 1 
ATOM   3294 C  CD2 . LEU A 1 432 ? 40.19548  -0.33442  -30.83243 1.000 17.20685  ?  432 LEU A CD2 1 
ATOM   3295 N  N   . VAL A 1 433 ? 39.98348  -4.80580  -34.46864 1.000 17.05927  ?  433 VAL A N   1 
ATOM   3296 C  CA  . VAL A 1 433 ? 40.35944  -6.21927  -34.55320 1.000 19.39713  ?  433 VAL A CA  1 
ATOM   3297 C  C   . VAL A 1 433 ? 41.87272  -6.41612  -34.58709 1.000 19.69406  ?  433 VAL A C   1 
ATOM   3298 O  O   . VAL A 1 433 ? 42.37798  -7.26901  -33.83734 1.000 26.88903  ?  433 VAL A O   1 
ATOM   3299 C  CB  . VAL A 1 433 ? 39.64511  -6.88427  -35.74377 1.000 22.18439  ?  433 VAL A CB  1 
ATOM   3300 C  CG1 . VAL A 1 433 ? 40.01818  -8.35655  -35.83553 1.000 25.65929  ?  433 VAL A CG1 1 
ATOM   3301 C  CG2 . VAL A 1 433 ? 38.13844  -6.71489  -35.61782 1.000 14.87180  ?  433 VAL A CG2 1 
ATOM   3302 N  N   . PRO A 1 434 ? 42.64634  -5.70144  -35.42004 1.000 16.37054  ?  434 PRO A N   1 
ATOM   3303 C  CA  . PRO A 1 434 ? 44.10946  -5.88347  -35.36559 1.000 18.75413  ?  434 PRO A CA  1 
ATOM   3304 C  C   . PRO A 1 434 ? 44.71202  -5.53214  -34.01651 1.000 19.80080  ?  434 PRO A C   1 
ATOM   3305 O  O   . PRO A 1 434 ? 45.65808  -6.19559  -33.56620 1.000 25.71269  ?  434 PRO A O   1 
ATOM   3306 C  CB  . PRO A 1 434 ? 44.61801  -4.95155  -36.47521 1.000 21.85207  ?  434 PRO A CB  1 
ATOM   3307 C  CG  . PRO A 1 434 ? 43.46230  -4.78817  -37.39395 1.000 22.85144  ?  434 PRO A CG  1 
ATOM   3308 C  CD  . PRO A 1 434 ? 42.26287  -4.77644  -36.50235 1.000 19.99326  ?  434 PRO A CD  1 
ATOM   3309 N  N   . LEU A 1 435 ? 44.18410  -4.50037  -33.35357 1.000 15.75751  ?  435 LEU A N   1 
ATOM   3310 C  CA  . LEU A 1 435 ? 44.67935  -4.14870  -32.02759 1.000 16.66350  ?  435 LEU A CA  1 
ATOM   3311 C  C   . LEU A 1 435 ? 44.41960  -5.27361  -31.03446 1.000 17.24382  ?  435 LEU A C   1 
ATOM   3312 O  O   . LEU A 1 435 ? 45.26744  -5.56944  -30.18526 1.000 21.07803  ?  435 LEU A O   1 
ATOM   3313 C  CB  . LEU A 1 435 ? 44.04375  -2.83980  -31.55975 1.000 18.39020  ?  435 LEU A CB  1 
ATOM   3314 C  CG  . LEU A 1 435 ? 44.41630  -1.62316  -32.41159 1.000 18.42662  ?  435 LEU A CG  1 
ATOM   3315 C  CD1 . LEU A 1 435 ? 43.79114  -0.35304  -31.85998 1.000 15.53754  ?  435 LEU A CD1 1 
ATOM   3316 C  CD2 . LEU A 1 435 ? 45.92931  -1.48392  -32.50811 1.000 21.59525  ?  435 LEU A CD2 1 
ATOM   3317 N  N   . ILE A 1 436 ? 43.25811  -5.92378  -31.13568 1.000 18.45594  ?  436 ILE A N   1 
ATOM   3318 C  CA  . ILE A 1 436 ? 43.01777  -7.13219  -30.35257 1.000 20.36351  ?  436 ILE A CA  1 
ATOM   3319 C  C   . ILE A 1 436 ? 44.06225  -8.18787  -30.68399 1.000 22.85074  ?  436 ILE A C   1 
ATOM   3320 O  O   . ILE A 1 436 ? 44.61607  -8.84003  -29.79086 1.000 23.25287  ?  436 ILE A O   1 
ATOM   3321 C  CB  . ILE A 1 436 ? 41.59291  -7.66099  -30.60052 1.000 21.68402  ?  436 ILE A CB  1 
ATOM   3322 C  CG1 . ILE A 1 436 ? 40.55057  -6.64093  -30.14540 1.000 15.28516  ?  436 ILE A CG1 1 
ATOM   3323 C  CG2 . ILE A 1 436 ? 41.39149  -8.99759  -29.90108 1.000 22.91826  ?  436 ILE A CG2 1 
ATOM   3324 C  CD1 . ILE A 1 436 ? 39.12330  -7.12136  -30.29939 1.000 22.02976  ?  436 ILE A CD1 1 
ATOM   3325 N  N   . ALA A 1 437 ? 44.35787  -8.36233  -31.97318 1.000 22.72561  ?  437 ALA A N   1 
ATOM   3326 C  CA  . ALA A 1 437 ? 45.31611  -9.37360  -32.40055 1.000 18.91969  ?  437 ALA A CA  1 
ATOM   3327 C  C   . ALA A 1 437 ? 46.75156  -9.05002  -32.00323 1.000 31.56438  ?  437 ALA A C   1 
ATOM   3328 O  O   . ALA A 1 437 ? 47.61774  -9.92116  -32.13654 1.000 35.43942  ?  437 ALA A O   1 
ATOM   3329 C  CB  . ALA A 1 437 ? 45.23255  -9.56611  -33.91365 1.000 17.37381  ?  437 ALA A CB  1 
ATOM   3330 N  N   . ASP A 1 438 ? 47.03562  -7.83036  -31.54166 1.000 30.06016  ?  438 ASP A N   1 
ATOM   3331 C  CA  . ASP A 1 438 ? 48.36625  -7.48865  -31.04737 1.000 23.16211  ?  438 ASP A CA  1 
ATOM   3332 C  C   . ASP A 1 438 ? 48.36905  -7.18503  -29.54835 1.000 26.30330  ?  438 ASP A C   1 
ATOM   3333 O  O   . ASP A 1 438 ? 49.19826  -6.40674  -29.06993 1.000 27.24901  ?  438 ASP A O   1 
ATOM   3334 C  CB  . ASP A 1 438 ? 48.95268  -6.31332  -31.82761 1.000 22.27361  ?  438 ASP A CB  1 
ATOM   3335 C  CG  . ASP A 1 438 ? 50.46574  -6.22293  -31.69323 1.000 32.78902  ?  438 ASP A CG  1 
ATOM   3336 O  OD1 . ASP A 1 438 ? 51.06512  -7.14380  -31.09712 1.000 35.46364  ?  438 ASP A OD1 1 
ATOM   3337 O  OD2 . ASP A 1 438 ? 51.05430  -5.23257  -32.17601 1.000 41.80794  -1 438 ASP A OD2 1 
ATOM   3338 N  N   . ASP A 1 439 ? 47.45182  -7.79888  -28.79723 1.000 29.61267  ?  439 ASP A N   1 
ATOM   3339 C  CA  . ASP A 1 439 ? 47.37697  -7.65548  -27.34090 1.000 28.11862  ?  439 ASP A CA  1 
ATOM   3340 C  C   . ASP A 1 439 ? 47.27898  -6.18202  -26.93634 1.000 33.26769  ?  439 ASP A C   1 
ATOM   3341 O  O   . ASP A 1 439 ? 48.16334  -5.62128  -26.28525 1.000 32.47605  ?  439 ASP A O   1 
ATOM   3342 C  CB  . ASP A 1 439 ? 48.56831  -8.33969  -26.65867 1.000 31.24158  ?  439 ASP A CB  1 
ATOM   3343 C  CG  . ASP A 1 439 ? 48.43499  -8.37913  -25.14305 1.000 38.76067  ?  439 ASP A CG  1 
ATOM   3344 O  OD1 . ASP A 1 439 ? 47.32902  -8.10868  -24.62790 1.000 33.09280  ?  439 ASP A OD1 1 
ATOM   3345 O  OD2 . ASP A 1 439 ? 49.44166  -8.67615  -24.46556 1.000 41.33009  -1 439 ASP A OD2 1 
ATOM   3346 N  N   . TYR A 1 440 ? 46.18318  -5.55712  -27.35118 1.000 30.68396  ?  440 TYR A N   1 
ATOM   3347 C  CA  . TYR A 1 440 ? 45.98642  -4.17827  -26.93459 1.000 19.27918  ?  440 TYR A CA  1 
ATOM   3348 C  C   . TYR A 1 440 ? 45.04904  -4.12422  -25.73698 1.000 20.87486  ?  440 TYR A C   1 
ATOM   3349 O  O   . TYR A 1 440 ? 44.11772  -4.93220  -25.64483 1.000 23.15473  ?  440 TYR A O   1 
ATOM   3350 C  CB  . TYR A 1 440 ? 45.40222  -3.34787  -28.07758 1.000 21.46590  ?  440 TYR A CB  1 
ATOM   3351 C  CG  . TYR A 1 440 ? 45.41566  -1.86271  -27.82847 1.000 28.53016  ?  440 TYR A CG  1 
ATOM   3352 C  CD1 . TYR A 1 440 ? 46.53849  -1.10202  -28.12376 1.000 27.05396  ?  440 TYR A CD1 1 
ATOM   3353 C  CD2 . TYR A 1 440 ? 44.30772  -1.21989  -27.29628 1.000 28.91887  ?  440 TYR A CD2 1 
ATOM   3354 C  CE1 . TYR A 1 440 ? 46.55758  0.25531   -27.89583 1.000 21.63894  ?  440 TYR A CE1 1 
ATOM   3355 C  CE2 . TYR A 1 440 ? 44.31846  0.13671   -27.06334 1.000 28.61291  ?  440 TYR A CE2 1 
ATOM   3356 C  CZ  . TYR A 1 440 ? 45.44489  0.86885   -27.36626 1.000 30.08588  ?  440 TYR A CZ  1 
ATOM   3357 O  OH  . TYR A 1 440 ? 45.45713  2.22108   -27.13873 1.000 35.32745  ?  440 TYR A OH  1 
ATOM   3358 N  N   . PRO A 1 441 ? 45.27009  -3.20869  -24.78689 1.000 23.66299  ?  441 PRO A N   1 
ATOM   3359 C  CA  . PRO A 1 441 ? 44.34306  -3.10000  -23.65213 1.000 18.49391  ?  441 PRO A CA  1 
ATOM   3360 C  C   . PRO A 1 441 ? 42.93725  -2.74910  -24.10616 1.000 20.41666  ?  441 PRO A C   1 
ATOM   3361 O  O   . PRO A 1 441 ? 42.68536  -1.63679  -24.58142 1.000 25.14198  ?  441 PRO A O   1 
ATOM   3362 C  CB  . PRO A 1 441 ? 44.95821  -1.98167  -22.79903 1.000 25.66064  ?  441 PRO A CB  1 
ATOM   3363 C  CG  . PRO A 1 441 ? 45.86683  -1.23213  -23.73816 1.000 25.23484  ?  441 PRO A CG  1 
ATOM   3364 C  CD  . PRO A 1 441 ? 46.40463  -2.27919  -24.66137 1.000 22.22186  ?  441 PRO A CD  1 
ATOM   3365 N  N   . ILE A 1 442 ? 42.01116  -3.69547  -23.95914 1.000 19.72855  ?  442 ILE A N   1 
ATOM   3366 C  CA  . ILE A 1 442 ? 40.63664  -3.52341  -24.40964 1.000 20.35878  ?  442 ILE A CA  1 
ATOM   3367 C  C   . ILE A 1 442 ? 39.69676  -4.18210  -23.41268 1.000 16.97771  ?  442 ILE A C   1 
ATOM   3368 O  O   . ILE A 1 442 ? 40.05878  -5.13597  -22.71703 1.000 14.19252  ?  442 ILE A O   1 
ATOM   3369 C  CB  . ILE A 1 442 ? 40.38348  -4.11710  -25.81559 1.000 16.91739  ?  442 ILE A CB  1 
ATOM   3370 C  CG1 . ILE A 1 442 ? 40.61169  -5.62797  -25.79736 1.000 21.00819  ?  442 ILE A CG1 1 
ATOM   3371 C  CG2 . ILE A 1 442 ? 41.24349  -3.43628  -26.87633 1.000 17.56123  ?  442 ILE A CG2 1 
ATOM   3372 C  CD1 . ILE A 1 442 ? 39.73168  -6.37802  -26.75690 1.000 36.42206  ?  442 ILE A CD1 1 
ATOM   3373 N  N   . VAL A 1 443 ? 38.47804  -3.65588  -23.35008 1.000 18.99328  ?  443 VAL A N   1 
ATOM   3374 C  CA  . VAL A 1 443 ? 37.37168  -4.28248  -22.64171 1.000 18.95383  ?  443 VAL A CA  1 
ATOM   3375 C  C   . VAL A 1 443 ? 36.16631  -4.25076  -23.56644 1.000 16.69208  ?  443 VAL A C   1 
ATOM   3376 O  O   . VAL A 1 443 ? 36.07565  -3.40831  -24.46458 1.000 14.14382  ?  443 VAL A O   1 
ATOM   3377 C  CB  . VAL A 1 443 ? 37.05640  -3.58766  -21.29818 1.000 16.53551  ?  443 VAL A CB  1 
ATOM   3378 C  CG1 . VAL A 1 443 ? 38.21880  -3.75286  -20.33029 1.000 17.08099  ?  443 VAL A CG1 1 
ATOM   3379 C  CG2 . VAL A 1 443 ? 36.74224  -2.12249  -21.52144 1.000 19.62086  ?  443 VAL A CG2 1 
ATOM   3380 N  N   . ILE A 1 444 ? 35.25267  -5.19534  -23.36709 1.000 16.30368  ?  444 ILE A N   1 
ATOM   3381 C  CA  . ILE A 1 444 ? 34.04170  -5.30271  -24.17317 1.000 17.78708  ?  444 ILE A CA  1 
ATOM   3382 C  C   . ILE A 1 444 ? 32.84831  -4.92563  -23.30771 1.000 17.41109  ?  444 ILE A C   1 
ATOM   3383 O  O   . ILE A 1 444 ? 32.67708  -5.45754  -22.20288 1.000 14.54509  ?  444 ILE A O   1 
ATOM   3384 C  CB  . ILE A 1 444 ? 33.87635  -6.71401  -24.76566 1.000 13.47449  ?  444 ILE A CB  1 
ATOM   3385 C  CG1 . ILE A 1 444 ? 34.91378  -6.95133  -25.86328 1.000 9.55690   ?  444 ILE A CG1 1 
ATOM   3386 C  CG2 . ILE A 1 444 ? 32.46947  -6.90447  -25.32259 1.000 13.15412  ?  444 ILE A CG2 1 
ATOM   3387 C  CD1 . ILE A 1 444 ? 34.75895  -6.03691  -27.05416 1.000 9.01939   ?  444 ILE A CD1 1 
ATOM   3388 N  N   . SER A 1 445 ? 32.03007  -4.00552  -23.81047 1.000 15.46316  ?  445 SER A N   1 
ATOM   3389 C  CA  . SER A 1 445 ? 30.83963  -3.54685  -23.11831 1.000 16.30746  ?  445 SER A CA  1 
ATOM   3390 C  C   . SER A 1 445 ? 29.73671  -3.34883  -24.14374 1.000 17.22410  ?  445 SER A C   1 
ATOM   3391 O  O   . SER A 1 445 ? 29.94218  -3.49110  -25.35310 1.000 17.12999  ?  445 SER A O   1 
ATOM   3392 C  CB  . SER A 1 445 ? 31.09522  -2.25246  -22.33285 1.000 18.26362  ?  445 SER A CB  1 
ATOM   3393 O  OG  . SER A 1 445 ? 30.04075  -1.98892  -21.42173 1.000 18.62522  ?  445 SER A OG  1 
ATOM   3394 N  N   . SER A 1 446 ? 28.55286  -3.01566  -23.64553 1.000 19.58818  ?  446 SER A N   1 
ATOM   3395 C  CA  . SER A 1 446 ? 27.36996  -2.94802  -24.48467 1.000 19.17571  ?  446 SER A CA  1 
ATOM   3396 C  C   . SER A 1 446 ? 26.90767  -1.52782  -24.79301 1.000 22.88300  ?  446 SER A C   1 
ATOM   3397 O  O   . SER A 1 446 ? 25.97903  -1.36595  -25.59100 1.000 23.58052  ?  446 SER A O   1 
ATOM   3398 C  CB  . SER A 1 446 ? 26.23089  -3.71885  -23.82020 1.000 25.49366  ?  446 SER A CB  1 
ATOM   3399 O  OG  . SER A 1 446 ? 26.19725  -3.45993  -22.42706 1.000 22.22920  ?  446 SER A OG  1 
ATOM   3400 N  N   . ASP A 1 447 ? 27.52733  -0.50199  -24.19708 1.000 26.37853  ?  447 ASP A N   1 
ATOM   3401 C  CA  . ASP A 1 447 ? 27.03486  0.87030   -24.30662 1.000 27.34978  ?  447 ASP A CA  1 
ATOM   3402 C  C   . ASP A 1 447 ? 25.59842  0.93081   -23.81782 1.000 30.00933  ?  447 ASP A C   1 
ATOM   3403 O  O   . ASP A 1 447 ? 25.33788  0.83804   -22.61576 1.000 44.37388  ?  447 ASP A O   1 
ATOM   3404 C  CB  . ASP A 1 447 ? 27.13425  1.42058   -25.73617 1.000 25.27460  ?  447 ASP A CB  1 
ATOM   3405 C  CG  . ASP A 1 447 ? 27.79150  2.80126   -25.78807 1.000 22.78884  ?  447 ASP A CG  1 
ATOM   3406 O  OD1 . ASP A 1 447 ? 27.95839  3.46902   -24.73421 1.000 23.24226  ?  447 ASP A OD1 1 
ATOM   3407 O  OD2 . ASP A 1 447 ? 28.16680  3.20655   -26.90865 1.000 24.60333  -1 447 ASP A OD2 1 
ATOM   3408 N  N   . ASP A 1 448 ? 24.65650  1.11518   -24.72889 1.000 24.21714  ?  448 ASP A N   1 
ATOM   3409 C  CA  . ASP A 1 448 ? 23.25895  1.12736   -24.32948 1.000 22.93772  ?  448 ASP A CA  1 
ATOM   3410 C  C   . ASP A 1 448 ? 22.54183  -0.12713  -24.81011 1.000 23.74095  ?  448 ASP A C   1 
ATOM   3411 O  O   . ASP A 1 448 ? 22.01252  -0.14200  -25.92775 1.000 21.49416  ?  448 ASP A O   1 
ATOM   3412 C  CB  . ASP A 1 448 ? 22.55400  2.36348   -24.88687 1.000 27.82998  ?  448 ASP A CB  1 
ATOM   3413 C  CG  . ASP A 1 448 ? 23.37579  3.62525   -24.74728 1.000 26.70708  ?  448 ASP A CG  1 
ATOM   3414 O  OD1 . ASP A 1 448 ? 24.17685  3.88854   -25.66641 1.000 18.75957  ?  448 ASP A OD1 1 
ATOM   3415 O  OD2 . ASP A 1 448 ? 23.19714  4.36540   -23.75089 1.000 44.61534  -1 448 ASP A OD2 1 
ATOM   3416 N  N   . PRO A 1 449 ? 22.44320  -1.16816  -23.97749 1.000 22.93351  ?  449 PRO A N   1 
ATOM   3417 C  CA  . PRO A 1 449 ? 21.86057  -2.43425  -24.46207 1.000 19.75528  ?  449 PRO A CA  1 
ATOM   3418 C  C   . PRO A 1 449 ? 20.36557  -2.37103  -24.71708 1.000 20.57397  ?  449 PRO A C   1 
ATOM   3419 O  O   . PRO A 1 449 ? 19.89625  -2.92188  -25.71987 1.000 20.69559  ?  449 PRO A O   1 
ATOM   3420 C  CB  . PRO A 1 449 ? 22.18991  -3.43028  -23.33653 1.000 19.81109  ?  449 PRO A CB  1 
ATOM   3421 C  CG  . PRO A 1 449 ? 23.14794  -2.72748  -22.43396 1.000 20.33930  ?  449 PRO A CG  1 
ATOM   3422 C  CD  . PRO A 1 449 ? 22.91818  -1.26762  -22.59032 1.000 22.84172  ?  449 PRO A CD  1 
ATOM   3423 N  N   . GLY A 1 450 ? 19.60106  -1.72042  -23.83680 1.000 20.56462  ?  450 GLY A N   1 
ATOM   3424 C  CA  . GLY A 1 450 ? 18.15218  -1.81209  -23.91147 1.000 20.48017  ?  450 GLY A CA  1 
ATOM   3425 C  C   . GLY A 1 450 ? 17.55680  -1.18454  -25.15450 1.000 20.34312  ?  450 GLY A C   1 
ATOM   3426 O  O   . GLY A 1 450 ? 16.49323  -1.60894  -25.61617 1.000 19.50281  ?  450 GLY A O   1 
ATOM   3427 N  N   . ALA A 1 451 ? 18.22590  -0.17312  -25.71199 1.000 19.66421  ?  451 ALA A N   1 
ATOM   3428 C  CA  . ALA A 1 451 ? 17.67331  0.54119   -26.85812 1.000 18.93059  ?  451 ALA A CA  1 
ATOM   3429 C  C   . ALA A 1 451 ? 17.45032  -0.39013  -28.04364 1.000 22.71901  ?  451 ALA A C   1 
ATOM   3430 O  O   . ALA A 1 451 ? 16.41946  -0.30500  -28.72112 1.000 23.26604  ?  451 ALA A O   1 
ATOM   3431 C  CB  . ALA A 1 451 ? 18.59335  1.69738   -27.24721 1.000 22.23104  ?  451 ALA A CB  1 
ATOM   3432 N  N   . TRP A 1 452 ? 18.40027  -1.28770  -28.31051 1.000 25.95863  ?  452 TRP A N   1 
ATOM   3433 C  CA  . TRP A 1 452 ? 18.29893  -2.22333  -29.42426 1.000 21.07897  ?  452 TRP A CA  1 
ATOM   3434 C  C   . TRP A 1 452 ? 18.07267  -3.66105  -28.95969 1.000 19.59385  ?  452 TRP A C   1 
ATOM   3435 O  O   . TRP A 1 452 ? 18.46589  -4.60751  -29.64680 1.000 22.26254  ?  452 TRP A O   1 
ATOM   3436 C  CB  . TRP A 1 452 ? 19.53778  -2.13665  -30.31349 1.000 18.64968  ?  452 TRP A CB  1 
ATOM   3437 C  CG  . TRP A 1 452 ? 20.83890  -2.03509  -29.57153 1.000 19.80470  ?  452 TRP A CG  1 
ATOM   3438 C  CD1 . TRP A 1 452 ? 21.48508  -3.03446  -28.90165 1.000 21.89311  ?  452 TRP A CD1 1 
ATOM   3439 C  CD2 . TRP A 1 452 ? 21.66517  -0.87111  -29.44852 1.000 17.91973  ?  452 TRP A CD2 1 
ATOM   3440 N  NE1 . TRP A 1 452 ? 22.65713  -2.56119  -28.36130 1.000 22.96608  ?  452 TRP A NE1 1 
ATOM   3441 C  CE2 . TRP A 1 452 ? 22.79146  -1.23630  -28.68411 1.000 21.21449  ?  452 TRP A CE2 1 
ATOM   3442 C  CE3 . TRP A 1 452 ? 21.55967  0.44515   -29.90725 1.000 20.95140  ?  452 TRP A CE3 1 
ATOM   3443 C  CZ2 . TRP A 1 452 ? 23.80509  -0.33241  -28.36855 1.000 22.83673  ?  452 TRP A CZ2 1 
ATOM   3444 C  CZ3 . TRP A 1 452 ? 22.56623  1.34054   -29.59229 1.000 24.59515  ?  452 TRP A CZ3 1 
ATOM   3445 C  CH2 . TRP A 1 452 ? 23.67335  0.94806   -28.82925 1.000 21.71295  ?  452 TRP A CH2 1 
ATOM   3446 N  N   . GLU A 1 453 ? 17.43410  -3.83002  -27.80157 1.000 17.45920  ?  453 GLU A N   1 
ATOM   3447 C  CA  . GLU A 1 453 ? 17.01653  -5.13281  -27.27816 1.000 17.59505  ?  453 GLU A CA  1 
ATOM   3448 C  C   . GLU A 1 453 ? 18.16164  -6.14727  -27.30506 1.000 17.55206  ?  453 GLU A C   1 
ATOM   3449 O  O   . GLU A 1 453 ? 18.09884  -7.18878  -27.96041 1.000 14.58798  ?  453 GLU A O   1 
ATOM   3450 C  CB  . GLU A 1 453 ? 15.80069  -5.66253  -28.04329 1.000 13.90365  ?  453 GLU A CB  1 
ATOM   3451 C  CG  . GLU A 1 453 ? 14.59317  -4.74085  -28.02510 1.000 12.90953  ?  453 GLU A CG  1 
ATOM   3452 C  CD  . GLU A 1 453 ? 13.40989  -5.32156  -28.77629 1.000 20.57522  ?  453 GLU A CD  1 
ATOM   3453 O  OE1 . GLU A 1 453 ? 13.13873  -6.53056  -28.61422 1.000 13.67809  ?  453 GLU A OE1 1 
ATOM   3454 O  OE2 . GLU A 1 453 ? 12.75790  -4.57389  -29.53649 1.000 24.19576  -1 453 GLU A OE2 1 
ATOM   3455 N  N   . ALA A 1 454 ? 19.21937  -5.82489  -26.57034 1.000 18.44578  ?  454 ALA A N   1 
ATOM   3456 C  CA  . ALA A 1 454 ? 20.38173  -6.68903  -26.46268 1.000 16.41672  ?  454 ALA A CA  1 
ATOM   3457 C  C   . ALA A 1 454 ? 20.55586  -7.13804  -25.01882 1.000 17.88951  ?  454 ALA A C   1 
ATOM   3458 O  O   . ALA A 1 454 ? 20.10375  -6.47628  -24.08036 1.000 21.71525  ?  454 ALA A O   1 
ATOM   3459 C  CB  . ALA A 1 454 ? 21.65037  -5.97986  -26.95126 1.000 20.05438  ?  454 ALA A CB  1 
ATOM   3460 N  N   . SER A 1 455 ? 21.21042  -8.28138  -24.85010 1.000 15.24659  ?  455 SER A N   1 
ATOM   3461 C  CA  . SER A 1 455 ? 21.48792  -8.76947  -23.51016 1.000 15.94446  ?  455 SER A CA  1 
ATOM   3462 C  C   . SER A 1 455 ? 22.61091  -7.94448  -22.88283 1.000 17.51141  ?  455 SER A C   1 
ATOM   3463 O  O   . SER A 1 455 ? 23.42425  -7.35584  -23.60143 1.000 23.44668  ?  455 SER A O   1 
ATOM   3464 C  CB  . SER A 1 455 ? 21.87269  -10.24500 -23.54870 1.000 18.59961  ?  455 SER A CB  1 
ATOM   3465 O  OG  . SER A 1 455 ? 23.11073  -10.43057 -24.20166 1.000 18.87767  ?  455 SER A OG  1 
ATOM   3466 N  N   . PRO A 1 456 ? 22.66838  -7.88485  -21.53584 1.000 12.53591  ?  456 PRO A N   1 
ATOM   3467 C  CA  . PRO A 1 456 ? 23.62361  -6.99365  -20.85491 1.000 19.61401  ?  456 PRO A CA  1 
ATOM   3468 C  C   . PRO A 1 456 ? 25.05436  -7.04142  -21.38337 1.000 28.30813  ?  456 PRO A C   1 
ATOM   3469 O  O   . PRO A 1 456 ? 25.58729  -6.00941  -21.80124 1.000 26.43129  ?  456 PRO A O   1 
ATOM   3470 C  CB  . PRO A 1 456 ? 23.54349  -7.47272  -19.39931 1.000 20.63862  ?  456 PRO A CB  1 
ATOM   3471 C  CG  . PRO A 1 456 ? 22.14852  -7.93462  -19.25716 1.000 16.13620  ?  456 PRO A CG  1 
ATOM   3472 C  CD  . PRO A 1 456 ? 21.76565  -8.54895  -20.57789 1.000 12.65334  ?  456 PRO A CD  1 
ATOM   3473 N  N   . LEU A 1 457 ? 25.70295  -8.20603  -21.35255 1.000 24.18435  ?  457 LEU A N   1 
ATOM   3474 C  CA  . LEU A 1 457 ? 27.02331  -8.32391  -21.96581 1.000 21.41781  ?  457 LEU A CA  1 
ATOM   3475 C  C   . LEU A 1 457 ? 27.21778  -9.59107  -22.78624 1.000 21.25375  ?  457 LEU A C   1 
ATOM   3476 O  O   . LEU A 1 457 ? 28.22038  -9.68244  -23.50030 1.000 18.97712  ?  457 LEU A O   1 
ATOM   3477 C  CB  . LEU A 1 457 ? 28.12510  -8.24054  -20.89567 1.000 16.84317  ?  457 LEU A CB  1 
ATOM   3478 C  CG  . LEU A 1 457 ? 29.54730  -7.91275  -21.35452 1.000 18.22460  ?  457 LEU A CG  1 
ATOM   3479 C  CD1 . LEU A 1 457 ? 29.52320  -6.87040  -22.46022 1.000 21.22750  ?  457 LEU A CD1 1 
ATOM   3480 C  CD2 . LEU A 1 457 ? 30.35790  -7.41679  -20.17553 1.000 19.51303  ?  457 LEU A CD2 1 
ATOM   3481 N  N   . SER A 1 458 ? 26.30079  -10.56033 -22.73213 1.000 21.15808  ?  458 SER A N   1 
ATOM   3482 C  CA  . SER A 1 458 ? 26.53358  -11.83248 -23.40937 1.000 21.32605  ?  458 SER A CA  1 
ATOM   3483 C  C   . SER A 1 458 ? 26.40858  -11.71292 -24.92337 1.000 22.83835  ?  458 SER A C   1 
ATOM   3484 O  O   . SER A 1 458 ? 27.10498  -12.42454 -25.65296 1.000 23.54561  ?  458 SER A O   1 
ATOM   3485 C  CB  . SER A 1 458 ? 25.57126  -12.89561 -22.88334 1.000 21.32385  ?  458 SER A CB  1 
ATOM   3486 O  OG  . SER A 1 458 ? 25.84243  -13.20253 -21.52747 1.000 20.06195  ?  458 SER A OG  1 
ATOM   3487 N  N   . HIS A 1 459 ? 25.52117  -10.84703 -25.41726 1.000 22.94618  ?  459 HIS A N   1 
ATOM   3488 C  CA  . HIS A 1 459 ? 25.39271  -10.67932 -26.86176 1.000 20.85311  ?  459 HIS A CA  1 
ATOM   3489 C  C   . HIS A 1 459 ? 26.63335  -10.02257 -27.45054 1.000 19.01184  ?  459 HIS A C   1 
ATOM   3490 O  O   . HIS A 1 459 ? 27.14398  -10.46130 -28.48904 1.000 19.90284  ?  459 HIS A O   1 
ATOM   3491 C  CB  . HIS A 1 459 ? 24.14532  -9.86287  -27.19248 1.000 23.27541  ?  459 HIS A CB  1 
ATOM   3492 C  CG  . HIS A 1 459 ? 22.90307  -10.68550 -27.33414 1.000 18.96642  ?  459 HIS A CG  1 
ATOM   3493 N  ND1 . HIS A 1 459 ? 21.65072  -10.19318 -27.03956 1.000 17.35887  ?  459 HIS A ND1 1 
ATOM   3494 C  CD2 . HIS A 1 459 ? 22.71743  -11.96052 -27.75118 1.000 19.38657  ?  459 HIS A CD2 1 
ATOM   3495 C  CE1 . HIS A 1 459 ? 20.74729  -11.13107 -27.26095 1.000 18.35619  ?  459 HIS A CE1 1 
ATOM   3496 N  NE2 . HIS A 1 459 ? 21.36822  -12.21340 -27.69369 1.000 18.33388  ?  459 HIS A NE2 1 
ATOM   3497 N  N   . ASP A 1 460 ? 27.13870  -8.97366  -26.79716 1.000 23.66158  ?  460 ASP A N   1 
ATOM   3498 C  CA  . ASP A 1 460 ? 28.37267  -8.35112  -27.26127 1.000 25.25165  ?  460 ASP A CA  1 
ATOM   3499 C  C   . ASP A 1 460 ? 29.56163  -9.28588  -27.09133 1.000 22.87316  ?  460 ASP A C   1 
ATOM   3500 O  O   . ASP A 1 460 ? 30.49144  -9.25568  -27.90378 1.000 18.26960  ?  460 ASP A O   1 
ATOM   3501 C  CB  . ASP A 1 460 ? 28.61690  -7.03331  -26.52507 1.000 27.11353  ?  460 ASP A CB  1 
ATOM   3502 C  CG  . ASP A 1 460 ? 27.50940  -6.02217  -26.75485 1.000 31.24221  ?  460 ASP A CG  1 
ATOM   3503 O  OD1 . ASP A 1 460 ? 26.42509  -6.17729  -26.15197 1.000 30.90741  ?  460 ASP A OD1 1 
ATOM   3504 O  OD2 . ASP A 1 460 ? 27.72408  -5.07246  -27.53836 1.000 25.22134  -1 460 ASP A OD2 1 
ATOM   3505 N  N   . PHE A 1 461 ? 29.54902  -10.12485 -26.05278 1.000 21.57951  ?  461 PHE A N   1 
ATOM   3506 C  CA  . PHE A 1 461 ? 30.60424  -11.12087 -25.90266 1.000 19.39687  ?  461 PHE A CA  1 
ATOM   3507 C  C   . PHE A 1 461 ? 30.56066  -12.14780 -27.02690 1.000 17.61484  ?  461 PHE A C   1 
ATOM   3508 O  O   . PHE A 1 461 ? 31.60726  -12.54770 -27.54609 1.000 24.65224  ?  461 PHE A O   1 
ATOM   3509 C  CB  . PHE A 1 461 ? 30.49726  -11.80203 -24.54045 1.000 18.64258  ?  461 PHE A CB  1 
ATOM   3510 C  CG  . PHE A 1 461 ? 31.58667  -11.40973 -23.58456 1.000 20.63687  ?  461 PHE A CG  1 
ATOM   3511 C  CD1 . PHE A 1 461 ? 31.60508  -10.14764 -23.01562 1.000 15.06269  ?  461 PHE A CD1 1 
ATOM   3512 C  CD2 . PHE A 1 461 ? 32.59160  -12.30279 -23.25427 1.000 17.64607  ?  461 PHE A CD2 1 
ATOM   3513 C  CE1 . PHE A 1 461 ? 32.60401  -9.78291  -22.13562 1.000 14.86771  ?  461 PHE A CE1 1 
ATOM   3514 C  CE2 . PHE A 1 461 ? 33.59465  -11.94399 -22.37559 1.000 14.42065  ?  461 PHE A CE2 1 
ATOM   3515 C  CZ  . PHE A 1 461 ? 33.60056  -10.68227 -21.81515 1.000 15.43885  ?  461 PHE A CZ  1 
ATOM   3516 N  N   . TYR A 1 462 ? 29.36143  -12.58756 -27.41577 1.000 15.82920  ?  462 TYR A N   1 
ATOM   3517 C  CA  . TYR A 1 462 ? 29.24159  -13.50411 -28.54501 1.000 16.92395  ?  462 TYR A CA  1 
ATOM   3518 C  C   . TYR A 1 462 ? 29.72657  -12.85002 -29.82997 1.000 16.21600  ?  462 TYR A C   1 
ATOM   3519 O  O   . TYR A 1 462 ? 30.39553  -13.49126 -30.64957 1.000 17.09675  ?  462 TYR A O   1 
ATOM   3520 C  CB  . TYR A 1 462 ? 27.79288  -13.97232 -28.69740 1.000 21.61009  ?  462 TYR A CB  1 
ATOM   3521 C  CG  . TYR A 1 462 ? 27.59372  -14.98573 -29.80468 1.000 25.22326  ?  462 TYR A CG  1 
ATOM   3522 C  CD1 . TYR A 1 462 ? 27.70365  -16.34679 -29.55300 1.000 29.68015  ?  462 TYR A CD1 1 
ATOM   3523 C  CD2 . TYR A 1 462 ? 27.30058  -14.58188 -31.10170 1.000 21.38343  ?  462 TYR A CD2 1 
ATOM   3524 C  CE1 . TYR A 1 462 ? 27.52689  -17.27667 -30.56101 1.000 31.36449  ?  462 TYR A CE1 1 
ATOM   3525 C  CE2 . TYR A 1 462 ? 27.12559  -15.50419 -32.11484 1.000 21.56214  ?  462 TYR A CE2 1 
ATOM   3526 C  CZ  . TYR A 1 462 ? 27.23708  -16.84883 -31.83953 1.000 27.44440  ?  462 TYR A CZ  1 
ATOM   3527 O  OH  . TYR A 1 462 ? 27.05970  -17.76757 -32.84837 1.000 34.56799  ?  462 TYR A OH  1 
ATOM   3528 N  N   . VAL A 1 463 ? 29.38581  -11.57443 -30.02678 1.000 24.29353  ?  463 VAL A N   1 
ATOM   3529 C  CA  . VAL A 1 463 ? 29.84907  -10.85329 -31.20930 1.000 22.24325  ?  463 VAL A CA  1 
ATOM   3530 C  C   . VAL A 1 463 ? 31.36994  -10.76201 -31.21515 1.000 19.65934  ?  463 VAL A C   1 
ATOM   3531 O  O   . VAL A 1 463 ? 32.01450  -10.95952 -32.25150 1.000 24.16545  ?  463 VAL A O   1 
ATOM   3532 C  CB  . VAL A 1 463 ? 29.19372  -9.46147  -31.27715 1.000 15.69457  ?  463 VAL A CB  1 
ATOM   3533 C  CG1 . VAL A 1 463 ? 29.84642  -8.62142  -32.35609 1.000 12.60545  ?  463 VAL A CG1 1 
ATOM   3534 C  CG2 . VAL A 1 463 ? 27.70034  -9.59278  -31.53642 1.000 11.00378  ?  463 VAL A CG2 1 
ATOM   3535 N  N   . ALA A 1 464 ? 31.96721  -10.46519 -30.05938 1.000 17.71650  ?  464 ALA A N   1 
ATOM   3536 C  CA  . ALA A 1 464 ? 33.42235  -10.41449 -29.96825 1.000 20.39707  ?  464 ALA A CA  1 
ATOM   3537 C  C   . ALA A 1 464 ? 34.04209  -11.77436 -30.26500 1.000 21.20984  ?  464 ALA A C   1 
ATOM   3538 O  O   . ALA A 1 464 ? 35.04545  -11.86654 -30.98230 1.000 23.09928  ?  464 ALA A O   1 
ATOM   3539 C  CB  . ALA A 1 464 ? 33.84072  -9.92247  -28.58302 1.000 18.49110  ?  464 ALA A CB  1 
ATOM   3540 N  N   . LEU A 1 465 ? 33.45268  -12.84180 -29.72309 1.000 22.34679  ?  465 LEU A N   1 
ATOM   3541 C  CA  . LEU A 1 465 ? 33.97800  -14.18483 -29.94432 1.000 22.38008  ?  465 LEU A CA  1 
ATOM   3542 C  C   . LEU A 1 465 ? 33.91020  -14.57638 -31.41425 1.000 21.59624  ?  465 LEU A C   1 
ATOM   3543 O  O   . LEU A 1 465 ? 34.85377  -15.16695 -31.95068 1.000 20.01871  ?  465 LEU A O   1 
ATOM   3544 C  CB  . LEU A 1 465 ? 33.20663  -15.19203 -29.09038 1.000 19.37329  ?  465 LEU A CB  1 
ATOM   3545 C  CG  . LEU A 1 465 ? 33.24116  -16.65056 -29.55478 1.000 23.86590  ?  465 LEU A CG  1 
ATOM   3546 C  CD1 . LEU A 1 465 ? 34.60719  -17.27211 -29.30991 1.000 20.80573  ?  465 LEU A CD1 1 
ATOM   3547 C  CD2 . LEU A 1 465 ? 32.14351  -17.46086 -28.88259 1.000 22.66019  ?  465 LEU A CD2 1 
ATOM   3548 N  N   . MET A 1 466 ? 32.80380  -14.25998 -32.08147 1.000 22.90728  ?  466 MET A N   1 
ATOM   3549 C  CA  . MET A 1 466 ? 32.56919  -14.74291 -33.43426 1.000 19.57207  ?  466 MET A CA  1 
ATOM   3550 C  C   . MET A 1 466 ? 33.08441  -13.80858 -34.52303 1.000 22.51388  ?  466 MET A C   1 
ATOM   3551 O  O   . MET A 1 466 ? 33.19435  -14.23843 -35.67637 1.000 21.79738  ?  466 MET A O   1 
ATOM   3552 C  CB  . MET A 1 466 ? 31.07213  -14.98803 -33.64437 1.000 16.93404  ?  466 MET A CB  1 
ATOM   3553 C  CG  . MET A 1 466 ? 30.52118  -16.19143 -32.89553 1.000 18.90535  ?  466 MET A CG  1 
ATOM   3554 S  SD  . MET A 1 466 ? 31.10702  -17.76076 -33.56714 1.000 17.08118  ?  466 MET A SD  1 
ATOM   3555 C  CE  . MET A 1 466 ? 30.17388  -18.92503 -32.57479 1.000 19.98874  ?  466 MET A CE  1 
ATOM   3556 N  N   . ASP A 1 467 ? 33.41047  -12.55632 -34.19975 1.000 21.45460  ?  467 ASP A N   1 
ATOM   3557 C  CA  . ASP A 1 467 ? 33.77586  -11.57963 -35.21992 1.000 14.15318  ?  467 ASP A CA  1 
ATOM   3558 C  C   . ASP A 1 467 ? 35.09437  -10.86287 -34.97890 1.000 15.58420  ?  467 ASP A C   1 
ATOM   3559 O  O   . ASP A 1 467 ? 35.67832  -10.36462 -35.94838 1.000 21.34380  ?  467 ASP A O   1 
ATOM   3560 C  CB  . ASP A 1 467 ? 32.67419  -10.51748 -35.36759 1.000 15.83308  ?  467 ASP A CB  1 
ATOM   3561 C  CG  . ASP A 1 467 ? 31.38509  -11.08520 -35.92854 1.000 18.59730  ?  467 ASP A CG  1 
ATOM   3562 O  OD1 . ASP A 1 467 ? 31.45622  -12.02054 -36.75288 1.000 20.67036  ?  467 ASP A OD1 1 
ATOM   3563 O  OD2 . ASP A 1 467 ? 30.30105  -10.59425 -35.54673 1.000 13.82502  -1 467 ASP A OD2 1 
ATOM   3564 N  N   . LEU A 1 468 ? 35.58375  -10.78225 -33.74338 1.000 20.78566  ?  468 LEU A N   1 
ATOM   3565 C  CA  . LEU A 1 468 ? 36.74534  -9.95946  -33.43364 1.000 25.80319  ?  468 LEU A CA  1 
ATOM   3566 C  C   . LEU A 1 468 ? 38.01820  -10.76203 -33.19674 1.000 25.71650  ?  468 LEU A C   1 
ATOM   3567 O  O   . LEU A 1 468 ? 39.06988  -10.16431 -32.94268 1.000 26.57470  ?  468 LEU A O   1 
ATOM   3568 C  CB  . LEU A 1 468 ? 36.45072  -9.07641  -32.21488 1.000 22.35238  ?  468 LEU A CB  1 
ATOM   3569 C  CG  . LEU A 1 468 ? 35.17102  -8.23733  -32.30604 1.000 22.83333  ?  468 LEU A CG  1 
ATOM   3570 C  CD1 . LEU A 1 468 ? 35.05996  -7.28021  -31.12803 1.000 23.54511  ?  468 LEU A CD1 1 
ATOM   3571 C  CD2 . LEU A 1 468 ? 35.08943  -7.48165  -33.62703 1.000 19.70807  ?  468 LEU A CD2 1 
ATOM   3572 N  N   . CYS A 1 469 ? 37.96117  -12.08988 -33.27712 1.000 25.57946  ?  469 CYS A N   1 
ATOM   3573 C  CA  . CYS A 1 469 ? 39.14379  -12.92242 -33.10963 1.000 30.61219  ?  469 CYS A CA  1 
ATOM   3574 C  C   . CYS A 1 469 ? 39.11352  -14.04775 -34.13352 1.000 27.70160  ?  469 CYS A C   1 
ATOM   3575 O  O   . CYS A 1 469 ? 38.06746  -14.37427 -34.70077 1.000 24.15113  ?  469 CYS A O   1 
ATOM   3576 C  CB  . CYS A 1 469 ? 39.24942  -13.48688 -31.68514 1.000 25.70869  ?  469 CYS A CB  1 
ATOM   3577 S  SG  . CYS A 1 469 ? 37.77871  -14.34890 -31.10302 1.000 19.02813  ?  469 CYS A SG  1 
ATOM   3578 N  N   . GLY A 1 470 ? 40.28181  -14.64197 -34.35807 1.000 24.89221  ?  470 GLY A N   1 
ATOM   3579 C  CA  . GLY A 1 470 ? 40.44015  -15.59391 -35.43585 1.000 24.08567  ?  470 GLY A CA  1 
ATOM   3580 C  C   . GLY A 1 470 ? 39.81808  -16.94704 -35.14506 1.000 21.90489  ?  470 GLY A C   1 
ATOM   3581 O  O   . GLY A 1 470 ? 39.33189  -17.24005 -34.05203 1.000 21.67323  ?  470 GLY A O   1 
ATOM   3582 N  N   . ARG A 1 471 ? 39.85997  -17.79643 -36.17512 1.000 20.13025  ?  471 ARG A N   1 
ATOM   3583 C  CA  . ARG A 1 471 ? 39.22211  -19.10935 -36.11370 1.000 20.23948  ?  471 ARG A CA  1 
ATOM   3584 C  C   . ARG A 1 471 ? 39.81036  -19.98170 -35.01044 1.000 20.22285  ?  471 ARG A C   1 
ATOM   3585 O  O   . ARG A 1 471 ? 39.11551  -20.84909 -34.46850 1.000 15.72628  ?  471 ARG A O   1 
ATOM   3586 C  CB  . ARG A 1 471 ? 39.35065  -19.80242 -37.47153 1.000 17.94645  ?  471 ARG A CB  1 
ATOM   3587 C  CG  . ARG A 1 471 ? 38.72244  -21.18232 -37.55329 1.000 15.54834  ?  471 ARG A CG  1 
ATOM   3588 C  CD  . ARG A 1 471 ? 39.00911  -21.83242 -38.89860 1.000 17.25156  ?  471 ARG A CD  1 
ATOM   3589 N  NE  . ARG A 1 471 ? 38.36107  -23.13159 -39.03104 1.000 17.48121  ?  471 ARG A NE  1 
ATOM   3590 C  CZ  . ARG A 1 471 ? 38.90887  -24.28240 -38.66596 1.000 17.79047  ?  471 ARG A CZ  1 
ATOM   3591 N  NH1 . ARG A 1 471 ? 40.12082  -24.33411 -38.13786 1.000 16.78952  ?  471 ARG A NH1 1 
ATOM   3592 N  NH2 . ARG A 1 471 ? 38.22311  -25.40948 -38.83420 1.000 19.13028  ?  471 ARG A NH2 1 
ATOM   3593 N  N   . ASP A 1 472 ? 41.07976  -19.76988 -34.66095 1.000 21.43968  ?  472 ASP A N   1 
ATOM   3594 C  CA  . ASP A 1 472 ? 41.75321  -20.55439 -33.63335 1.000 18.15532  ?  472 ASP A CA  1 
ATOM   3595 C  C   . ASP A 1 472 ? 41.74682  -19.85900 -32.27367 1.000 18.87610  ?  472 ASP A C   1 
ATOM   3596 O  O   . ASP A 1 472 ? 42.67389  -20.04474 -31.47842 1.000 18.39434  ?  472 ASP A O   1 
ATOM   3597 C  CB  . ASP A 1 472 ? 43.18557  -20.86721 -34.06776 1.000 16.06238  ?  472 ASP A CB  1 
ATOM   3598 C  CG  . ASP A 1 472 ? 43.24886  -21.55885 -35.42077 1.000 16.45976  ?  472 ASP A CG  1 
ATOM   3599 O  OD1 . ASP A 1 472 ? 42.29710  -22.29190 -35.76268 1.000 13.43606  ?  472 ASP A OD1 1 
ATOM   3600 O  OD2 . ASP A 1 472 ? 44.25016  -21.37005 -36.14418 1.000 16.79292  -1 472 ASP A OD2 1 
ATOM   3601 N  N   . THR A 1 473 ? 40.71744  -19.05896 -31.99131 1.000 24.10203  ?  473 THR A N   1 
ATOM   3602 C  CA  . THR A 1 473 ? 40.62690  -18.29743 -30.74566 1.000 20.54001  ?  473 THR A CA  1 
ATOM   3603 C  C   . THR A 1 473 ? 39.19699  -18.38429 -30.22853 1.000 17.71358  ?  473 THR A C   1 
ATOM   3604 O  O   . THR A 1 473 ? 38.29561  -17.77057 -30.80785 1.000 16.81217  ?  473 THR A O   1 
ATOM   3605 C  CB  . THR A 1 473 ? 41.02566  -16.83712 -30.96341 1.000 15.05656  ?  473 THR A CB  1 
ATOM   3606 O  OG1 . THR A 1 473 ? 42.20880  -16.77281 -31.76837 1.000 12.74659  ?  473 THR A OG1 1 
ATOM   3607 C  CG2 . THR A 1 473 ? 41.28211  -16.15070 -29.63302 1.000 20.37587  ?  473 THR A CG2 1 
ATOM   3608 N  N   . ALA A 1 474 ? 38.97658  -19.14860 -29.15506 1.000 12.31623  ?  474 ALA A N   1 
ATOM   3609 C  CA  . ALA A 1 474 ? 37.63949  -19.26051 -28.57802 1.000 18.31728  ?  474 ALA A CA  1 
ATOM   3610 C  C   . ALA A 1 474 ? 37.55339  -18.75165 -27.14482 1.000 26.95665  ?  474 ALA A C   1 
ATOM   3611 O  O   . ALA A 1 474 ? 36.77917  -17.82771 -26.87510 1.000 30.98076  ?  474 ALA A O   1 
ATOM   3612 C  CB  . ALA A 1 474 ? 37.15762  -20.71338 -28.64810 1.000 23.09264  ?  474 ALA A CB  1 
ATOM   3613 N  N   . LEU A 1 475 ? 38.32814  -19.31106 -26.21421 1.000 29.52965  ?  475 LEU A N   1 
ATOM   3614 C  CA  . LEU A 1 475 ? 38.09667  -19.07392 -24.79304 1.000 30.74571  ?  475 LEU A CA  1 
ATOM   3615 C  C   . LEU A 1 475 ? 39.15001  -18.20760 -24.12694 1.000 26.59267  ?  475 LEU A C   1 
ATOM   3616 O  O   . LEU A 1 475 ? 38.81909  -17.46677 -23.19722 1.000 27.85873  ?  475 LEU A O   1 
ATOM   3617 C  CB  . LEU A 1 475 ? 38.00508  -20.40434 -24.03409 1.000 24.94363  ?  475 LEU A CB  1 
ATOM   3618 C  CG  . LEU A 1 475 ? 37.65572  -20.29615 -22.54734 1.000 21.14340  ?  475 LEU A CG  1 
ATOM   3619 C  CD1 . LEU A 1 475 ? 36.34616  -19.54363 -22.35911 1.000 16.20176  ?  475 LEU A CD1 1 
ATOM   3620 C  CD2 . LEU A 1 475 ? 37.58634  -21.66922 -21.90294 1.000 30.84009  ?  475 LEU A CD2 1 
ATOM   3621 N  N   . THR A 1 476 ? 40.40830  -18.29311 -24.56159 1.000 27.47054  ?  476 THR A N   1 
ATOM   3622 C  CA  . THR A 1 476 ? 41.42214  -17.38778 -24.03539 1.000 30.52485  ?  476 THR A CA  1 
ATOM   3623 C  C   . THR A 1 476 ? 41.00202  -15.93880 -24.23679 1.000 32.26668  ?  476 THR A C   1 
ATOM   3624 O  O   . THR A 1 476 ? 41.18264  -15.10061 -23.34699 1.000 40.31899  ?  476 THR A O   1 
ATOM   3625 C  CB  . THR A 1 476 ? 42.76926  -17.65757 -24.70595 1.000 33.25855  ?  476 THR A CB  1 
ATOM   3626 O  OG1 . THR A 1 476 ? 42.67644  -17.37193 -26.10735 1.000 40.38079  ?  476 THR A OG1 1 
ATOM   3627 C  CG2 . THR A 1 476 ? 43.18096  -19.11078 -24.51424 1.000 28.04715  ?  476 THR A CG2 1 
ATOM   3628 N  N   . PHE A 1 477 ? 40.39882  -15.64071 -25.38874 1.000 32.44048  ?  477 PHE A N   1 
ATOM   3629 C  CA  . PHE A 1 477 ? 39.93111  -14.28898 -25.67662 1.000 33.38305  ?  477 PHE A CA  1 
ATOM   3630 C  C   . PHE A 1 477 ? 38.85746  -13.84796 -24.68518 1.000 26.15428  ?  477 PHE A C   1 
ATOM   3631 O  O   . PHE A 1 477 ? 38.93233  -12.75061 -24.11764 1.000 26.09476  ?  477 PHE A O   1 
ATOM   3632 C  CB  . PHE A 1 477 ? 39.41243  -14.23783 -27.11541 1.000 32.99174  ?  477 PHE A CB  1 
ATOM   3633 C  CG  . PHE A 1 477 ? 38.79045  -12.93004 -27.49979 1.000 28.18799  ?  477 PHE A CG  1 
ATOM   3634 C  CD1 . PHE A 1 477 ? 39.53753  -11.76424 -27.50309 1.000 35.05200  ?  477 PHE A CD1 1 
ATOM   3635 C  CD2 . PHE A 1 477 ? 37.46242  -12.87193 -27.88752 1.000 16.46705  ?  477 PHE A CD2 1 
ATOM   3636 C  CE1 . PHE A 1 477 ? 38.96475  -10.55946 -27.86636 1.000 28.79192  ?  477 PHE A CE1 1 
ATOM   3637 C  CE2 . PHE A 1 477 ? 36.88591  -11.67309 -28.25482 1.000 22.26100  ?  477 PHE A CE2 1 
ATOM   3638 C  CZ  . PHE A 1 477 ? 37.63792  -10.51418 -28.24514 1.000 24.31959  ?  477 PHE A CZ  1 
ATOM   3639 N  N   . LEU A 1 478 ? 37.85283  -14.69862 -24.45397 1.000 23.28687  ?  478 LEU A N   1 
ATOM   3640 C  CA  . LEU A 1 478 ? 36.76311  -14.32794 -23.55391 1.000 24.55655  ?  478 LEU A CA  1 
ATOM   3641 C  C   . LEU A 1 478 ? 37.24928  -14.17971 -22.11614 1.000 25.93771  ?  478 LEU A C   1 
ATOM   3642 O  O   . LEU A 1 478 ? 36.86035  -13.23482 -21.41571 1.000 28.72523  ?  478 LEU A O   1 
ATOM   3643 C  CB  . LEU A 1 478 ? 35.63709  -15.35872 -23.63751 1.000 17.93678  ?  478 LEU A CB  1 
ATOM   3644 C  CG  . LEU A 1 478 ? 34.98176  -15.53161 -25.00927 1.000 21.71276  ?  478 LEU A CG  1 
ATOM   3645 C  CD1 . LEU A 1 478 ? 33.76757  -16.44239 -24.91498 1.000 22.44243  ?  478 LEU A CD1 1 
ATOM   3646 C  CD2 . LEU A 1 478 ? 34.60159  -14.18333 -25.60111 1.000 21.65807  ?  478 LEU A CD2 1 
ATOM   3647 N  N   . LYS A 1 479 ? 38.09873  -15.10070 -21.65445 1.000 27.15505  ?  479 LYS A N   1 
ATOM   3648 C  CA  . LYS A 1 479 ? 38.60591  -14.99080 -20.29171 1.000 22.78264  ?  479 LYS A CA  1 
ATOM   3649 C  C   . LYS A 1 479 ? 39.51498  -13.77927 -20.13077 1.000 22.22758  ?  479 LYS A C   1 
ATOM   3650 O  O   . LYS A 1 479 ? 39.51719  -13.14696 -19.06878 1.000 20.81290  ?  479 LYS A O   1 
ATOM   3651 C  CB  . LYS A 1 479 ? 39.33819  -16.26902 -19.88341 1.000 27.23679  ?  479 LYS A CB  1 
ATOM   3652 C  CG  . LYS A 1 479 ? 39.61094  -16.34531 -18.38815 1.000 25.14791  ?  479 LYS A CG  1 
ATOM   3653 C  CD  . LYS A 1 479 ? 40.18061  -17.68865 -17.97322 1.000 19.92532  ?  479 LYS A CD  1 
ATOM   3654 C  CE  . LYS A 1 479 ? 40.27640  -17.78571 -16.45903 1.000 17.60336  ?  479 LYS A CE  1 
ATOM   3655 N  NZ  . LYS A 1 479 ? 40.78125  -19.10938 -16.00746 1.000 23.79637  ?  479 LYS A NZ  1 
ATOM   3656 N  N   . GLN A 1 480 ? 40.28182  -13.42821 -21.16678 1.000 21.38399  ?  480 GLN A N   1 
ATOM   3657 C  CA  . GLN A 1 480 ? 41.09761  -12.22302 -21.09138 1.000 22.54079  ?  480 GLN A CA  1 
ATOM   3658 C  C   . GLN A 1 480 ? 40.23129  -10.97196 -21.06122 1.000 25.68159  ?  480 GLN A C   1 
ATOM   3659 O  O   . GLN A 1 480 ? 40.57103  -9.99682  -20.38568 1.000 26.05233  ?  480 GLN A O   1 
ATOM   3660 C  CB  . GLN A 1 480 ? 42.07284  -12.16661 -22.26259 1.000 22.09557  ?  480 GLN A CB  1 
ATOM   3661 C  CG  . GLN A 1 480 ? 43.19769  -11.17309 -22.05300 1.000 25.73048  ?  480 GLN A CG  1 
ATOM   3662 C  CD  . GLN A 1 480 ? 44.06010  -11.52947 -20.86099 1.000 27.17955  ?  480 GLN A CD  1 
ATOM   3663 O  OE1 . GLN A 1 480 ? 44.39247  -12.69536 -20.64891 1.000 29.05143  ?  480 GLN A OE1 1 
ATOM   3664 N  NE2 . GLN A 1 480 ? 44.42009  -10.52682 -20.06891 1.000 27.44840  ?  480 GLN A NE2 1 
ATOM   3665 N  N   . LEU A 1 481 ? 39.11899  -10.97084 -21.80038 1.000 21.89306  ?  481 LEU A N   1 
ATOM   3666 C  CA  . LEU A 1 481 ? 38.17894  -9.85770  -21.70005 1.000 14.99185  ?  481 LEU A CA  1 
ATOM   3667 C  C   . LEU A 1 481 ? 37.61331  -9.74625  -20.29025 1.000 19.95427  ?  481 LEU A C   1 
ATOM   3668 O  O   . LEU A 1 481 ? 37.51701  -8.64455  -19.73232 1.000 24.64250  ?  481 LEU A O   1 
ATOM   3669 C  CB  . LEU A 1 481 ? 37.04827  -10.02841 -22.71231 1.000 13.43937  ?  481 LEU A CB  1 
ATOM   3670 C  CG  . LEU A 1 481 ? 37.41804  -9.88405  -24.18503 1.000 12.21488  ?  481 LEU A CG  1 
ATOM   3671 C  CD1 . LEU A 1 481 ? 36.20771  -10.16609 -25.05063 1.000 15.96895  ?  481 LEU A CD1 1 
ATOM   3672 C  CD2 . LEU A 1 481 ? 37.96149  -8.49650  -24.45237 1.000 15.86242  ?  481 LEU A CD2 1 
ATOM   3673 N  N   . ALA A 1 482 ? 37.24209  -10.88333 -19.69667 1.000 18.02489  ?  482 ALA A N   1 
ATOM   3674 C  CA  . ALA A 1 482 ? 36.71261  -10.87333 -18.33628 1.000 19.58677  ?  482 ALA A CA  1 
ATOM   3675 C  C   . ALA A 1 482 ? 37.75396  -10.37542 -17.33951 1.000 21.44141  ?  482 ALA A C   1 
ATOM   3676 O  O   . ALA A 1 482 ? 37.41975  -9.67528  -16.37711 1.000 18.76118  ?  482 ALA A O   1 
ATOM   3677 C  CB  . ALA A 1 482 ? 36.22375  -12.26987 -17.95416 1.000 14.48155  ?  482 ALA A CB  1 
ATOM   3678 N  N   . LEU A 1 483 ? 39.02090  -10.73888 -17.54491 1.000 19.76311  ?  483 LEU A N   1 
ATOM   3679 C  CA  . LEU A 1 483 ? 40.07842  -10.27082 -16.65357 1.000 19.13271  ?  483 LEU A CA  1 
ATOM   3680 C  C   . LEU A 1 483 ? 40.35024  -8.78173  -16.84008 1.000 18.55622  ?  483 LEU A C   1 
ATOM   3681 O  O   . LEU A 1 483 ? 40.52652  -8.04916  -15.85890 1.000 20.25760  ?  483 LEU A O   1 
ATOM   3682 C  CB  . LEU A 1 483 ? 41.35140  -11.08348 -16.88418 1.000 22.63826  ?  483 LEU A CB  1 
ATOM   3683 C  CG  . LEU A 1 483 ? 41.33010  -12.51975 -16.36017 1.000 21.34520  ?  483 LEU A CG  1 
ATOM   3684 C  CD1 . LEU A 1 483 ? 42.57744  -13.26906 -16.79640 1.000 26.00041  ?  483 LEU A CD1 1 
ATOM   3685 C  CD2 . LEU A 1 483 ? 41.20665  -12.52236 -14.84557 1.000 19.25962  ?  483 LEU A CD2 1 
ATOM   3686 N  N   . ASN A 1 484 ? 40.39321  -8.31738  -18.09137 1.000 21.04372  ?  484 ASN A N   1 
ATOM   3687 C  CA  . ASN A 1 484 ? 40.65622  -6.90908  -18.36136 1.000 17.92944  ?  484 ASN A CA  1 
ATOM   3688 C  C   . ASN A 1 484 ? 39.52395  -6.02252  -17.86769 1.000 21.71478  ?  484 ASN A C   1 
ATOM   3689 O  O   . ASN A 1 484 ? 39.75926  -4.85930  -17.52272 1.000 27.54134  ?  484 ASN A O   1 
ATOM   3690 C  CB  . ASN A 1 484 ? 40.88377  -6.69055  -19.85776 1.000 16.47417  ?  484 ASN A CB  1 
ATOM   3691 C  CG  . ASN A 1 484 ? 42.19519  -7.27831  -20.34165 1.000 21.55459  ?  484 ASN A CG  1 
ATOM   3692 O  OD1 . ASN A 1 484 ? 42.79783  -8.11709  -19.67338 1.000 24.49901  ?  484 ASN A OD1 1 
ATOM   3693 N  ND2 . ASN A 1 484 ? 42.64472  -6.83771  -21.51102 1.000 27.72322  ?  484 ASN A ND2 1 
ATOM   3694 N  N   . SER A 1 485 ? 38.29402  -6.54373  -17.83138 1.000 23.22299  ?  485 SER A N   1 
ATOM   3695 C  CA  . SER A 1 485 ? 37.19076  -5.76515  -17.28092 1.000 20.84426  ?  485 SER A CA  1 
ATOM   3696 C  C   . SER A 1 485 ? 37.41450  -5.41734  -15.81500 1.000 21.72861  ?  485 SER A C   1 
ATOM   3697 O  O   . SER A 1 485 ? 36.85334  -4.42841  -15.33092 1.000 28.43717  ?  485 SER A O   1 
ATOM   3698 C  CB  . SER A 1 485 ? 35.87254  -6.52185  -17.44267 1.000 20.60626  ?  485 SER A CB  1 
ATOM   3699 O  OG  . SER A 1 485 ? 35.76256  -7.56207  -16.49032 1.000 19.60549  ?  485 SER A OG  1 
ATOM   3700 N  N   . ILE A 1 486 ? 38.21853  -6.20215  -15.10178 1.000 22.65130  ?  486 ILE A N   1 
ATOM   3701 C  CA  . ILE A 1 486 ? 38.56641  -5.88227  -13.72088 1.000 20.70018  ?  486 ILE A CA  1 
ATOM   3702 C  C   . ILE A 1 486 ? 39.88735  -5.12649  -13.64138 1.000 21.21810  ?  486 ILE A C   1 
ATOM   3703 O  O   . ILE A 1 486 ? 40.00661  -4.16117  -12.88291 1.000 23.86758  ?  486 ILE A O   1 
ATOM   3704 C  CB  . ILE A 1 486 ? 38.60357  -7.16754  -12.87036 1.000 17.85012  ?  486 ILE A CB  1 
ATOM   3705 C  CG1 . ILE A 1 486 ? 37.23775  -7.85504  -12.87990 1.000 13.12979  ?  486 ILE A CG1 1 
ATOM   3706 C  CG2 . ILE A 1 486 ? 39.03235  -6.85277  -11.44368 1.000 14.27057  ?  486 ILE A CG2 1 
ATOM   3707 C  CD1 . ILE A 1 486 ? 37.17655  -9.09641  -12.01889 1.000 12.38339  ?  486 ILE A CD1 1 
ATOM   3708 N  N   . ARG A 1 487 ? 40.89570  -5.54796  -14.41183 1.000 19.60865  ?  487 ARG A N   1 
ATOM   3709 C  CA  . ARG A 1 487 ? 42.19290  -4.87834  -14.35532 1.000 21.01176  ?  487 ARG A CA  1 
ATOM   3710 C  C   . ARG A 1 487 ? 42.07924  -3.41672  -14.76873 1.000 21.51688  ?  487 ARG A C   1 
ATOM   3711 O  O   . ARG A 1 487 ? 42.60762  -2.52449  -14.09528 1.000 20.18744  ?  487 ARG A O   1 
ATOM   3712 C  CB  . ARG A 1 487 ? 43.21390  -5.59205  -15.24281 1.000 20.76826  ?  487 ARG A CB  1 
ATOM   3713 C  CG  . ARG A 1 487 ? 44.36849  -4.67075  -15.62320 1.000 28.80100  ?  487 ARG A CG  1 
ATOM   3714 C  CD  . ARG A 1 487 ? 45.58160  -5.38709  -16.18322 1.000 37.92625  ?  487 ARG A CD  1 
ATOM   3715 N  NE  . ARG A 1 487 ? 46.69194  -4.45264  -16.33452 1.000 37.93409  ?  487 ARG A NE  1 
ATOM   3716 C  CZ  . ARG A 1 487 ? 47.87926  -4.76230  -16.83673 1.000 41.70172  ?  487 ARG A CZ  1 
ATOM   3717 N  NH1 . ARG A 1 487 ? 48.15354  -5.98498  -17.26026 1.000 40.85723  ?  487 ARG A NH1 1 
ATOM   3718 N  NH2 . ARG A 1 487 ? 48.81498  -3.81998  -16.91709 1.000 41.80251  ?  487 ARG A NH2 1 
ATOM   3719 N  N   . TYR A 1 488 ? 41.38720  -3.15070  -15.87357 1.000 22.70730  ?  488 TYR A N   1 
ATOM   3720 C  CA  . TYR A 1 488 ? 41.28242  -1.80395  -16.41192 1.000 25.62924  ?  488 TYR A CA  1 
ATOM   3721 C  C   . TYR A 1 488 ? 40.02773  -1.07859  -15.94211 1.000 22.97244  ?  488 TYR A C   1 
ATOM   3722 O  O   . TYR A 1 488 ? 39.59138  -0.12476  -16.59657 1.000 17.81955  ?  488 TYR A O   1 
ATOM   3723 C  CB  . TYR A 1 488 ? 41.33742  -1.84503  -17.93942 1.000 20.87339  ?  488 TYR A CB  1 
ATOM   3724 C  CG  . TYR A 1 488 ? 42.62805  -2.42089  -18.47522 1.000 20.37117  ?  488 TYR A CG  1 
ATOM   3725 C  CD1 . TYR A 1 488 ? 43.79737  -1.67133  -18.47632 1.000 25.78040  ?  488 TYR A CD1 1 
ATOM   3726 C  CD2 . TYR A 1 488 ? 42.67850  -3.71453  -18.97737 1.000 24.92624  ?  488 TYR A CD2 1 
ATOM   3727 C  CE1 . TYR A 1 488 ? 44.98192  -2.19374  -18.96384 1.000 31.11614  ?  488 TYR A CE1 1 
ATOM   3728 C  CE2 . TYR A 1 488 ? 43.85753  -4.24643  -19.46838 1.000 29.06256  ?  488 TYR A CE2 1 
ATOM   3729 C  CZ  . TYR A 1 488 ? 45.00630  -3.48173  -19.45934 1.000 33.83860  ?  488 TYR A CZ  1 
ATOM   3730 O  OH  . TYR A 1 488 ? 46.18237  -4.00593  -19.94656 1.000 26.76826  ?  488 TYR A OH  1 
ATOM   3731 N  N   . SER A 1 489 ? 39.44120  -1.50669  -14.82758 1.000 18.76987  ?  489 SER A N   1 
ATOM   3732 C  CA  . SER A 1 489 ? 38.34606  -0.77032  -14.22053 1.000 17.78257  ?  489 SER A CA  1 
ATOM   3733 C  C   . SER A 1 489 ? 38.89704  0.43021   -13.45362 1.000 23.72544  ?  489 SER A C   1 
ATOM   3734 O  O   . SER A 1 489 ? 40.09648  0.72095   -13.47571 1.000 25.97146  ?  489 SER A O   1 
ATOM   3735 C  CB  . SER A 1 489 ? 37.53257  -1.68161  -13.30520 1.000 15.28100  ?  489 SER A CB  1 
ATOM   3736 O  OG  . SER A 1 489 ? 38.28047  -2.04263  -12.15892 1.000 14.59497  ?  489 SER A OG  1 
ATOM   3737 N  N   . ALA A 1 490 ? 38.00968  1.14310   -12.76413 1.000 21.47803  ?  490 ALA A N   1 
ATOM   3738 C  CA  . ALA A 1 490 ? 38.39643  2.29171   -11.95752 1.000 22.52033  ?  490 ALA A CA  1 
ATOM   3739 C  C   . ALA A 1 490 ? 38.51697  1.95726   -10.47559 1.000 21.56330  ?  490 ALA A C   1 
ATOM   3740 O  O   . ALA A 1 490 ? 38.74410  2.86035   -9.66353  1.000 17.33867  ?  490 ALA A O   1 
ATOM   3741 C  CB  . ALA A 1 490 ? 37.40229  3.43583   -12.15795 1.000 23.89751  ?  490 ALA A CB  1 
ATOM   3742 N  N   . MET A 1 491 ? 38.37166  0.68695   -10.10712 1.000 22.74534  ?  491 MET A N   1 
ATOM   3743 C  CA  . MET A 1 491 ? 38.47489  0.29132   -8.71049  1.000 25.16295  ?  491 MET A CA  1 
ATOM   3744 C  C   . MET A 1 491 ? 39.89262  0.49541   -8.19000  1.000 30.18469  ?  491 MET A C   1 
ATOM   3745 O  O   . MET A 1 491 ? 40.86904  0.45622   -8.94356  1.000 26.47628  ?  491 MET A O   1 
ATOM   3746 C  CB  . MET A 1 491 ? 38.07553  -1.17470  -8.53463  1.000 23.13622  ?  491 MET A CB  1 
ATOM   3747 C  CG  . MET A 1 491 ? 36.58758  -1.44808  -8.64372  1.000 26.10896  ?  491 MET A CG  1 
ATOM   3748 S  SD  . MET A 1 491 ? 36.20492  -3.19561  -8.41776  1.000 25.50438  ?  491 MET A SD  1 
ATOM   3749 C  CE  . MET A 1 491 ? 37.04027  -3.90345  -9.83340  1.000 20.74297  ?  491 MET A CE  1 
ATOM   3750 N  N   . SER A 1 492 ? 39.99678  0.72057   -6.88180  1.000 28.17555  ?  492 SER A N   1 
ATOM   3751 C  CA  . SER A 1 492 ? 41.29576  0.73004   -6.23098  1.000 27.30469  ?  492 SER A CA  1 
ATOM   3752 C  C   . SER A 1 492 ? 41.93068  -0.65599  -6.33194  1.000 30.56018  ?  492 SER A C   1 
ATOM   3753 O  O   . SER A 1 492 ? 41.28079  -1.63998  -6.68252  1.000 31.46418  ?  492 SER A O   1 
ATOM   3754 C  CB  . SER A 1 492 ? 41.16034  1.15359   -4.76915  1.000 30.82445  ?  492 SER A CB  1 
ATOM   3755 O  OG  . SER A 1 492 ? 40.32019  0.26202   -4.05560  1.000 26.45460  ?  492 SER A OG  1 
ATOM   3756 N  N   . ASP A 1 493 ? 43.22775  -0.72541  -6.02496  1.000 29.16344  ?  493 ASP A N   1 
ATOM   3757 C  CA  . ASP A 1 493 ? 43.93789  -1.99688  -6.14048  1.000 25.32128  ?  493 ASP A CA  1 
ATOM   3758 C  C   . ASP A 1 493 ? 43.37925  -3.04015  -5.17711  1.000 27.06251  ?  493 ASP A C   1 
ATOM   3759 O  O   . ASP A 1 493 ? 43.21996  -4.21164  -5.54400  1.000 29.69332  ?  493 ASP A O   1 
ATOM   3760 C  CB  . ASP A 1 493 ? 45.43302  -1.78377  -5.91114  1.000 27.93744  ?  493 ASP A CB  1 
ATOM   3761 C  CG  . ASP A 1 493 ? 46.10090  -1.07057  -7.07188  1.000 36.08701  ?  493 ASP A CG  1 
ATOM   3762 O  OD1 . ASP A 1 493 ? 45.39605  -0.73868  -8.04908  1.000 33.27152  ?  493 ASP A OD1 1 
ATOM   3763 O  OD2 . ASP A 1 493 ? 47.32819  -0.84529  -7.01071  1.000 39.83933  -1 493 ASP A OD2 1 
ATOM   3764 N  N   . THR A 1 494 ? 43.07148  -2.63450  -3.94257  1.000 19.19610  ?  494 THR A N   1 
ATOM   3765 C  CA  . THR A 1 494 ? 42.44121  -3.54891  -2.99386  1.000 16.54849  ?  494 THR A CA  1 
ATOM   3766 C  C   . THR A 1 494 ? 41.08851  -4.02522  -3.51255  1.000 22.52369  ?  494 THR A C   1 
ATOM   3767 O  O   . THR A 1 494 ? 40.76865  -5.22379  -3.46262  1.000 26.44104  ?  494 THR A O   1 
ATOM   3768 C  CB  . THR A 1 494 ? 42.28498  -2.85914  -1.63679  1.000 21.65685  ?  494 THR A CB  1 
ATOM   3769 O  OG1 . THR A 1 494 ? 43.57845  -2.58409  -1.08335  1.000 29.55453  ?  494 THR A OG1 1 
ATOM   3770 C  CG2 . THR A 1 494 ? 41.49586  -3.73379  -0.67287  1.000 32.15734  ?  494 THR A CG2 1 
ATOM   3771 N  N   . GLU A 1 495 ? 40.28181  -3.09146  -4.02392  1.000 23.10495  ?  495 GLU A N   1 
ATOM   3772 C  CA  . GLU A 1 495 ? 38.99956  -3.45926  -4.61093  1.000 27.39588  ?  495 GLU A CA  1 
ATOM   3773 C  C   . GLU A 1 495 ? 39.19045  -4.36249  -5.82007  1.000 30.76409  ?  495 GLU A C   1 
ATOM   3774 O  O   . GLU A 1 495 ? 38.38969  -5.27190  -6.05312  1.000 31.92329  ?  495 GLU A O   1 
ATOM   3775 C  CB  . GLU A 1 495 ? 38.21585  -2.20598  -4.99710  1.000 27.17317  ?  495 GLU A CB  1 
ATOM   3776 C  CG  . GLU A 1 495 ? 37.53880  -1.51247  -3.83223  1.000 27.56807  ?  495 GLU A CG  1 
ATOM   3777 C  CD  . GLU A 1 495 ? 36.70975  -0.32505  -4.27330  1.000 27.02268  ?  495 GLU A CD  1 
ATOM   3778 O  OE1 . GLU A 1 495 ? 37.01138  0.24477   -5.34270  1.000 33.75172  ?  495 GLU A OE1 1 
ATOM   3779 O  OE2 . GLU A 1 495 ? 35.75314  0.03458   -3.55594  1.000 28.67324  -1 495 GLU A OE2 1 
ATOM   3780 N  N   . LYS A 1 496 ? 40.24632  -4.12711  -6.60190  1.000 26.92318  ?  496 LYS A N   1 
ATOM   3781 C  CA  . LYS A 1 496 ? 40.52376  -4.98580  -7.74798  1.000 24.58112  ?  496 LYS A CA  1 
ATOM   3782 C  C   . LYS A 1 496 ? 40.83215  -6.41095  -7.30881  1.000 23.11627  ?  496 LYS A C   1 
ATOM   3783 O  O   . LYS A 1 496 ? 40.34555  -7.37126  -7.91514  1.000 24.35906  ?  496 LYS A O   1 
ATOM   3784 C  CB  . LYS A 1 496 ? 41.67747  -4.41197  -8.57131  1.000 18.51249  ?  496 LYS A CB  1 
ATOM   3785 C  CG  . LYS A 1 496 ? 41.27608  -3.24437  -9.45674  1.000 21.21868  ?  496 LYS A CG  1 
ATOM   3786 C  CD  . LYS A 1 496 ? 42.45737  -2.69848  -10.23853 1.000 18.80472  ?  496 LYS A CD  1 
ATOM   3787 C  CE  . LYS A 1 496 ? 42.03524  -1.53203  -11.11780 1.000 20.82609  ?  496 LYS A CE  1 
ATOM   3788 N  NZ  . LYS A 1 496 ? 43.19588  -0.87997  -11.78436 1.000 23.57845  ?  496 LYS A NZ  1 
ATOM   3789 N  N   . VAL A 1 497 ? 41.63149  -6.57078  -6.25151  1.000 23.14793  ?  497 VAL A N   1 
ATOM   3790 C  CA  . VAL A 1 497 ? 41.95775  -7.91281  -5.77002  1.000 23.42796  ?  497 VAL A CA  1 
ATOM   3791 C  C   . VAL A 1 497 ? 40.70415  -8.61331  -5.25504  1.000 21.25074  ?  497 VAL A C   1 
ATOM   3792 O  O   . VAL A 1 497 ? 40.45489  -9.78797  -5.56070  1.000 24.25757  ?  497 VAL A O   1 
ATOM   3793 C  CB  . VAL A 1 497 ? 43.05558  -7.84928  -4.69248  1.000 22.57434  ?  497 VAL A CB  1 
ATOM   3794 C  CG1 . VAL A 1 497 ? 43.32973  -9.23635  -4.13430  1.000 24.26249  ?  497 VAL A CG1 1 
ATOM   3795 C  CG2 . VAL A 1 497 ? 44.32955  -7.25069  -5.26841  1.000 20.70817  ?  497 VAL A CG2 1 
ATOM   3796 N  N   . ALA A 1 498 ? 39.89026  -7.89986  -4.47067  1.000 17.68754  ?  498 ALA A N   1 
ATOM   3797 C  CA  . ALA A 1 498 ? 38.66410  -8.50421  -3.95045  1.000 20.29254  ?  498 ALA A CA  1 
ATOM   3798 C  C   . ALA A 1 498 ? 37.70590  -8.88168  -5.07894  1.000 25.92926  ?  498 ALA A C   1 
ATOM   3799 O  O   . ALA A 1 498 ? 37.09346  -9.96229  -5.06017  1.000 28.13734  ?  498 ALA A O   1 
ATOM   3800 C  CB  . ALA A 1 498 ? 37.98949  -7.55120  -2.96475  1.000 17.32759  ?  498 ALA A CB  1 
ATOM   3801 N  N   . ALA A 1 499 ? 37.56583  -8.00112  -6.07301  1.000 25.67658  ?  499 ALA A N   1 
ATOM   3802 C  CA  . ALA A 1 499 ? 36.69360  -8.27747  -7.20632  1.000 25.90965  ?  499 ALA A CA  1 
ATOM   3803 C  C   . ALA A 1 499 ? 37.19533  -9.46692  -8.00989  1.000 28.33450  ?  499 ALA A C   1 
ATOM   3804 O  O   . ALA A 1 499 ? 36.39750  -10.28485 -8.48132  1.000 31.84559  ?  499 ALA A O   1 
ATOM   3805 C  CB  . ALA A 1 499 ? 36.58396  -7.03830  -8.09261  1.000 22.18368  ?  499 ALA A CB  1 
ATOM   3806 N  N   . LYS A 1 500 ? 38.51456  -9.57647  -8.18830  1.000 25.50320  ?  500 LYS A N   1 
ATOM   3807 C  CA  . LYS A 1 500 ? 39.05729  -10.73542 -8.88449  1.000 24.69979  ?  500 LYS A CA  1 
ATOM   3808 C  C   . LYS A 1 500 ? 38.78903  -12.01163 -8.10294  1.000 28.48779  ?  500 LYS A C   1 
ATOM   3809 O  O   . LYS A 1 500 ? 38.51873  -13.05843 -8.69463  1.000 30.96685  ?  500 LYS A O   1 
ATOM   3810 C  CB  . LYS A 1 500 ? 40.55538  -10.56951 -9.13561  1.000 19.90167  ?  500 LYS A CB  1 
ATOM   3811 C  CG  . LYS A 1 500 ? 41.14594  -11.72453 -9.93723  1.000 25.15846  ?  500 LYS A CG  1 
ATOM   3812 C  CD  . LYS A 1 500 ? 42.64042  -11.57999 -10.15912 1.000 50.32048  ?  500 LYS A CD  1 
ATOM   3813 C  CE  . LYS A 1 500 ? 43.18425  -12.76307 -10.94904 1.000 33.05819  ?  500 LYS A CE  1 
ATOM   3814 N  NZ  . LYS A 1 500 ? 44.65628  -12.67443 -11.15687 1.000 34.56011  ?  500 LYS A NZ  1 
ATOM   3815 N  N   . ALA A 1 501 ? 38.85626  -11.94659 -6.77176  1.000 26.07788  ?  501 ALA A N   1 
ATOM   3816 C  CA  . ALA A 1 501 ? 38.52984  -13.12126 -5.96599  1.000 24.29962  ?  501 ALA A CA  1 
ATOM   3817 C  C   . ALA A 1 501 ? 37.08347  -13.55770 -6.18798  1.000 24.02632  ?  501 ALA A C   1 
ATOM   3818 O  O   . ALA A 1 501 ? 36.80430  -14.74416 -6.41917  1.000 22.20510  ?  501 ALA A O   1 
ATOM   3819 C  CB  . ALA A 1 501 ? 38.78713  -12.83024 -4.48771  1.000 27.30400  ?  501 ALA A CB  1 
ATOM   3820 N  N   . LYS A 1 502 ? 36.14737  -12.60416 -6.12983  1.000 21.74329  ?  502 LYS A N   1 
ATOM   3821 C  CA  . LYS A 1 502 ? 34.73952  -12.94437 -6.34705  1.000 27.76540  ?  502 LYS A CA  1 
ATOM   3822 C  C   . LYS A 1 502 ? 34.50953  -13.49555 -7.75252  1.000 27.29091  ?  502 LYS A C   1 
ATOM   3823 O  O   . LYS A 1 502 ? 33.79876  -14.49952 -7.93798  1.000 27.90933  ?  502 LYS A O   1 
ATOM   3824 C  CB  . LYS A 1 502 ? 33.85395  -11.72015 -6.11063  1.000 27.84261  ?  502 LYS A CB  1 
ATOM   3825 C  CG  . LYS A 1 502 ? 33.61206  -11.37065 -4.65040  1.000 25.48727  ?  502 LYS A CG  1 
ATOM   3826 C  CD  . LYS A 1 502 ? 32.51767  -10.31784 -4.52993  1.000 28.78770  ?  502 LYS A CD  1 
ATOM   3827 C  CE  . LYS A 1 502 ? 32.28197  -9.90673  -3.08672  1.000 31.69176  ?  502 LYS A CE  1 
ATOM   3828 N  NZ  . LYS A 1 502 ? 31.22157  -8.86452  -2.98282  1.000 37.66145  ?  502 LYS A NZ  1 
ATOM   3829 N  N   . TRP A 1 503 ? 35.10525  -12.84904 -8.75662  1.000 25.11697  ?  503 TRP A N   1 
ATOM   3830 C  CA  . TRP A 1 503 ? 34.93580  -13.29887 -10.13089 1.000 24.79561  ?  503 TRP A CA  1 
ATOM   3831 C  C   . TRP A 1 503 ? 35.54480  -14.67733 -10.33887 1.000 27.55622  ?  503 TRP A C   1 
ATOM   3832 O  O   . TRP A 1 503 ? 35.00546  -15.48596 -11.09585 1.000 26.04572  ?  503 TRP A O   1 
ATOM   3833 C  CB  . TRP A 1 503 ? 35.55117  -12.29132 -11.09933 1.000 20.00341  ?  503 TRP A CB  1 
ATOM   3834 C  CG  . TRP A 1 503 ? 35.59044  -12.80112 -12.49971 1.000 22.55333  ?  503 TRP A CG  1 
ATOM   3835 C  CD1 . TRP A 1 503 ? 34.61261  -12.68506 -13.44330 1.000 23.60222  ?  503 TRP A CD1 1 
ATOM   3836 C  CD2 . TRP A 1 503 ? 36.65870  -13.52870 -13.11481 1.000 27.19972  ?  503 TRP A CD2 1 
ATOM   3837 N  NE1 . TRP A 1 503 ? 35.00928  -13.28994 -14.61148 1.000 24.73243  ?  503 TRP A NE1 1 
ATOM   3838 C  CE2 . TRP A 1 503 ? 36.26198  -13.81637 -14.43489 1.000 28.04406  ?  503 TRP A CE2 1 
ATOM   3839 C  CE3 . TRP A 1 503 ? 37.91304  -13.96387 -12.67698 1.000 22.73889  ?  503 TRP A CE3 1 
ATOM   3840 C  CZ2 . TRP A 1 503 ? 37.07547  -14.51708 -15.32151 1.000 26.58612  ?  503 TRP A CZ2 1 
ATOM   3841 C  CZ3 . TRP A 1 503 ? 38.71732  -14.65952 -13.55729 1.000 19.99599  ?  503 TRP A CZ3 1 
ATOM   3842 C  CH2 . TRP A 1 503 ? 38.29678  -14.92857 -14.86475 1.000 22.10306  ?  503 TRP A CH2 1 
ATOM   3843 N  N   . THR A 1 504 ? 36.67904  -14.95761 -9.69156  1.000 26.59379  ?  504 THR A N   1 
ATOM   3844 C  CA  . THR A 1 504 ? 37.28839  -16.27896 -9.79098  1.000 21.24708  ?  504 THR A CA  1 
ATOM   3845 C  C   . THR A 1 504 ? 36.39158  -17.34122 -9.17462  1.000 19.33673  ?  504 THR A C   1 
ATOM   3846 O  O   . THR A 1 504 ? 36.24983  -18.43964 -9.72522  1.000 20.71477  ?  504 THR A O   1 
ATOM   3847 C  CB  . THR A 1 504 ? 38.66059  -16.27873 -9.11425  1.000 20.59811  ?  504 THR A CB  1 
ATOM   3848 O  OG1 . THR A 1 504 ? 39.54064  -15.38762 -9.81034  1.000 22.98823  ?  504 THR A OG1 1 
ATOM   3849 C  CG2 . THR A 1 504 ? 39.26236  -17.67784 -9.11442  1.000 20.22977  ?  504 THR A CG2 1 
ATOM   3850 N  N   . THR A 1 505 ? 35.78195  -17.03506 -8.02674  1.000 21.02313  ?  505 THR A N   1 
ATOM   3851 C  CA  . THR A 1 505 ? 34.82022  -17.96483 -7.44018  1.000 21.03890  ?  505 THR A CA  1 
ATOM   3852 C  C   . THR A 1 505 ? 33.71019  -18.29350 -8.43282  1.000 22.27359  ?  505 THR A C   1 
ATOM   3853 O  O   . THR A 1 505 ? 33.43824  -19.47048 -8.72191  1.000 32.85493  ?  505 THR A O   1 
ATOM   3854 C  CB  . THR A 1 505 ? 34.23324  -17.37407 -6.15733  1.000 18.73931  ?  505 THR A CB  1 
ATOM   3855 O  OG1 . THR A 1 505 ? 35.28564  -17.12318 -5.21852  1.000 21.60537  ?  505 THR A OG1 1 
ATOM   3856 C  CG2 . THR A 1 505 ? 33.22534  -18.33168 -5.53991  1.000 17.93455  ?  505 THR A CG2 1 
ATOM   3857 N  N   . GLN A 1 506 ? 33.07979  -17.25559 -8.99215  1.000 22.16646  ?  506 GLN A N   1 
ATOM   3858 C  CA  . GLN A 1 506 ? 31.98230  -17.48630 -9.93052  1.000 20.46589  ?  506 GLN A CA  1 
ATOM   3859 C  C   . GLN A 1 506 ? 32.45930  -18.21911 -11.18203 1.000 23.52607  ?  506 GLN A C   1 
ATOM   3860 O  O   . GLN A 1 506 ? 31.76193  -19.09998 -11.70038 1.000 22.90705  ?  506 GLN A O   1 
ATOM   3861 C  CB  . GLN A 1 506 ? 31.31590  -16.16176 -10.29893 1.000 16.41767  ?  506 GLN A CB  1 
ATOM   3862 C  CG  . GLN A 1 506 ? 30.55048  -15.52930 -9.14945  1.000 29.32142  ?  506 GLN A CG  1 
ATOM   3863 C  CD  . GLN A 1 506 ? 29.50772  -16.46322 -8.56094  1.000 25.83193  ?  506 GLN A CD  1 
ATOM   3864 O  OE1 . GLN A 1 506 ? 28.77309  -17.13105 -9.28899  1.000 26.49711  ?  506 GLN A OE1 1 
ATOM   3865 N  NE2 . GLN A 1 506 ? 29.44392  -16.51893 -7.23539  1.000 22.94270  ?  506 GLN A NE2 1 
ATOM   3866 N  N   . TRP A 1 507 ? 33.64951  -17.87293 -11.67563 1.000 21.26180  ?  507 TRP A N   1 
ATOM   3867 C  CA  . TRP A 1 507 ? 34.17769  -18.47657 -12.89314 1.000 20.71526  ?  507 TRP A CA  1 
ATOM   3868 C  C   . TRP A 1 507 ? 34.45829  -19.95949 -12.70715 1.000 26.85729  ?  507 TRP A C   1 
ATOM   3869 O  O   . TRP A 1 507 ? 34.12546  -20.77170 -13.57735 1.000 31.66137  ?  507 TRP A O   1 
ATOM   3870 C  CB  . TRP A 1 507 ? 35.44662  -17.74049 -13.31992 1.000 25.07256  ?  507 TRP A CB  1 
ATOM   3871 C  CG  . TRP A 1 507 ? 36.13267  -18.34894 -14.49483 1.000 25.79629  ?  507 TRP A CG  1 
ATOM   3872 C  CD1 . TRP A 1 507 ? 37.09109  -19.31936 -14.47305 1.000 28.44412  ?  507 TRP A CD1 1 
ATOM   3873 C  CD2 . TRP A 1 507 ? 35.92046  -18.02441 -15.87227 1.000 28.59709  ?  507 TRP A CD2 1 
ATOM   3874 N  NE1 . TRP A 1 507 ? 37.48671  -19.62160 -15.75280 1.000 34.75031  ?  507 TRP A NE1 1 
ATOM   3875 C  CE2 . TRP A 1 507 ? 36.78286  -18.83954 -16.63056 1.000 37.51559  ?  507 TRP A CE2 1 
ATOM   3876 C  CE3 . TRP A 1 507 ? 35.08385  -17.12465 -16.53851 1.000 29.21469  ?  507 TRP A CE3 1 
ATOM   3877 C  CZ2 . TRP A 1 507 ? 36.83198  -18.78221 -18.02152 1.000 38.28634  ?  507 TRP A CZ2 1 
ATOM   3878 C  CZ3 . TRP A 1 507 ? 35.13618  -17.06832 -17.91807 1.000 30.57459  ?  507 TRP A CZ3 1 
ATOM   3879 C  CH2 . TRP A 1 507 ? 36.00244  -17.89226 -18.64497 1.000 30.96973  ?  507 TRP A CH2 1 
ATOM   3880 N  N   . ASP A 1 508 ? 35.08524  -20.33086 -11.58958 1.000 28.65202  ?  508 ASP A N   1 
ATOM   3881 C  CA  . ASP A 1 508 ? 35.34457  -21.74207 -11.33107 1.000 25.56940  ?  508 ASP A CA  1 
ATOM   3882 C  C   . ASP A 1 508 ? 34.04515  -22.51215 -11.14258 1.000 22.73757  ?  508 ASP A C   1 
ATOM   3883 O  O   . ASP A 1 508 ? 33.91543  -23.64715 -11.62415 1.000 29.28677  ?  508 ASP A O   1 
ATOM   3884 C  CB  . ASP A 1 508 ? 36.25621  -21.89728 -10.11527 1.000 22.60334  ?  508 ASP A CB  1 
ATOM   3885 C  CG  . ASP A 1 508 ? 37.69602  -21.53288 -10.42182 1.000 28.13007  ?  508 ASP A CG  1 
ATOM   3886 O  OD1 . ASP A 1 508 ? 38.10634  -21.67653 -11.59345 1.000 25.66710  ?  508 ASP A OD1 1 
ATOM   3887 O  OD2 . ASP A 1 508 ? 38.41755  -21.10593 -9.49582  1.000 38.18990  -1 508 ASP A OD2 1 
ATOM   3888 N  N   . LYS A 1 509 ? 33.06509  -21.90969 -10.46005 1.000 18.87902  ?  509 LYS A N   1 
ATOM   3889 C  CA  . LYS A 1 509 ? 31.76624  -22.56354 -10.33120 1.000 21.85273  ?  509 LYS A CA  1 
ATOM   3890 C  C   . LYS A 1 509 ? 31.15084  -22.82228 -11.70283 1.000 26.85640  ?  509 LYS A C   1 
ATOM   3891 O  O   . LYS A 1 509 ? 30.65695  -23.92371 -11.98198 1.000 26.06293  ?  509 LYS A O   1 
ATOM   3892 C  CB  . LYS A 1 509 ? 30.83472  -21.70794 -9.47287  1.000 19.72399  ?  509 LYS A CB  1 
ATOM   3893 C  CG  . LYS A 1 509 ? 29.61529  -22.44709 -8.94921  1.000 22.63775  ?  509 LYS A CG  1 
ATOM   3894 C  CD  . LYS A 1 509 ? 28.68570  -21.51058 -8.19234  1.000 28.17533  ?  509 LYS A CD  1 
ATOM   3895 C  CE  . LYS A 1 509 ? 29.43965  -20.69454 -7.15222  1.000 29.72704  ?  509 LYS A CE  1 
ATOM   3896 N  NZ  . LYS A 1 509 ? 30.14144  -21.55272 -6.15846  1.000 26.33939  ?  509 LYS A NZ  1 
ATOM   3897 N  N   . PHE A 1 510 ? 31.19394  -21.81576 -12.58056 1.000 26.97114  ?  510 PHE A N   1 
ATOM   3898 C  CA  . PHE A 1 510 ? 30.62710  -21.95830 -13.91844 1.000 27.51429  ?  510 PHE A CA  1 
ATOM   3899 C  C   . PHE A 1 510 ? 31.35438  -23.02747 -14.72526 1.000 27.37693  ?  510 PHE A C   1 
ATOM   3900 O  O   . PHE A 1 510 ? 30.71688  -23.83908 -15.40871 1.000 24.76758  ?  510 PHE A O   1 
ATOM   3901 C  CB  . PHE A 1 510 ? 30.66933  -20.61026 -14.63953 1.000 27.53015  ?  510 PHE A CB  1 
ATOM   3902 C  CG  . PHE A 1 510 ? 30.77937  -20.71666 -16.13551 1.000 24.10787  ?  510 PHE A CG  1 
ATOM   3903 C  CD1 . PHE A 1 510 ? 29.69282  -21.10945 -16.89887 1.000 28.24810  ?  510 PHE A CD1 1 
ATOM   3904 C  CD2 . PHE A 1 510 ? 31.96655  -20.40372 -16.77977 1.000 18.67349  ?  510 PHE A CD2 1 
ATOM   3905 C  CE1 . PHE A 1 510 ? 29.79170  -21.20097 -18.27566 1.000 29.42170  ?  510 PHE A CE1 1 
ATOM   3906 C  CE2 . PHE A 1 510 ? 32.07076  -20.49364 -18.15513 1.000 19.46099  ?  510 PHE A CE2 1 
ATOM   3907 C  CZ  . PHE A 1 510 ? 30.98154  -20.89353 -18.90376 1.000 23.93604  ?  510 PHE A CZ  1 
ATOM   3908 N  N   . VAL A 1 511 ? 32.68854  -23.04009 -14.66440 1.000 23.85788  ?  511 VAL A N   1 
ATOM   3909 C  CA  . VAL A 1 511 ? 33.45860  -24.02537 -15.42054 1.000 26.10219  ?  511 VAL A CA  1 
ATOM   3910 C  C   . VAL A 1 511 ? 33.10804  -25.43376 -14.96134 1.000 28.50464  ?  511 VAL A C   1 
ATOM   3911 O  O   . VAL A 1 511 ? 32.83967  -26.32617 -15.77881 1.000 27.77893  ?  511 VAL A O   1 
ATOM   3912 C  CB  . VAL A 1 511 ? 34.96768  -23.74979 -15.28823 1.000 26.65302  ?  511 VAL A CB  1 
ATOM   3913 C  CG1 . VAL A 1 511 ? 35.77247  -24.90541 -15.86915 1.000 25.49762  ?  511 VAL A CG1 1 
ATOM   3914 C  CG2 . VAL A 1 511 ? 35.33350  -22.44758 -15.98009 1.000 30.45632  ?  511 VAL A CG2 1 
ATOM   3915 N  N   . LYS A 1 512 ? 33.08776  -25.64880 -13.64134 1.000 32.18635  ?  512 LYS A N   1 
ATOM   3916 C  CA  . LYS A 1 512 ? 32.77322  -26.97347 -13.11652 1.000 28.88986  ?  512 LYS A CA  1 
ATOM   3917 C  C   . LYS A 1 512 ? 31.36753  -27.40507 -13.51632 1.000 30.98404  ?  512 LYS A C   1 
ATOM   3918 O  O   . LYS A 1 512 ? 31.16359  -28.54219 -13.96417 1.000 32.11287  ?  512 LYS A O   1 
ATOM   3919 C  CB  . LYS A 1 512 ? 32.93091  -26.98004 -11.59546 1.000 24.87718  ?  512 LYS A CB  1 
ATOM   3920 C  CG  . LYS A 1 512 ? 33.01937  -28.36608 -10.97690 1.000 40.78338  ?  512 LYS A CG  1 
ATOM   3921 C  CD  . LYS A 1 512 ? 33.38009  -28.27843 -9.50238  1.000 50.46842  ?  512 LYS A CD  1 
ATOM   3922 C  CE  . LYS A 1 512 ? 33.77760  -29.63215 -8.93610  1.000 52.63645  ?  512 LYS A CE  1 
ATOM   3923 N  NZ  . LYS A 1 512 ? 32.65305  -30.60379 -8.95579  1.000 74.54933  ?  512 LYS A NZ  1 
ATOM   3924 N  N   . THR A 1 513 ? 30.38969  -26.50256 -13.39104 1.000 30.27778  ?  513 THR A N   1 
ATOM   3925 C  CA  . THR A 1 513 ? 29.01151  -26.85860 -13.71432 1.000 24.91965  ?  513 THR A CA  1 
ATOM   3926 C  C   . THR A 1 513 ? 28.85952  -27.19666 -15.19295 1.000 24.38377  ?  513 THR A C   1 
ATOM   3927 O  O   . THR A 1 513 ? 28.23164  -28.20035 -15.54856 1.000 25.27466  ?  513 THR A O   1 
ATOM   3928 C  CB  . THR A 1 513 ? 28.06961  -25.71947 -13.32177 1.000 23.33593  ?  513 THR A CB  1 
ATOM   3929 O  OG1 . THR A 1 513 ? 28.20090  -25.45064 -11.92020 1.000 20.94626  ?  513 THR A OG1 1 
ATOM   3930 C  CG2 . THR A 1 513 ? 26.62405  -26.09183 -13.62523 1.000 22.37828  ?  513 THR A CG2 1 
ATOM   3931 N  N   . SER A 1 514 ? 29.43863  -26.37403 -16.07315 1.000 24.90032  ?  514 SER A N   1 
ATOM   3932 C  CA  . SER A 1 514 ? 29.30579  -26.61962 -17.50629 1.000 27.15290  ?  514 SER A CA  1 
ATOM   3933 C  C   . SER A 1 514 ? 29.97690  -27.92640 -17.90977 1.000 30.75996  ?  514 SER A C   1 
ATOM   3934 O  O   . SER A 1 514 ? 29.41087  -28.71556 -18.68212 1.000 27.80277  ?  514 SER A O   1 
ATOM   3935 C  CB  . SER A 1 514 ? 29.89547  -25.45006 -18.29249 1.000 21.39990  ?  514 SER A CB  1 
ATOM   3936 O  OG  . SER A 1 514 ? 29.32100  -24.22357 -17.88213 1.000 16.25080  ?  514 SER A OG  1 
ATOM   3937 N  N   . VAL A 1 515 ? 31.18219  -28.17904 -17.39096 1.000 36.83190  ?  515 VAL A N   1 
ATOM   3938 C  CA  . VAL A 1 515 ? 31.88577  -29.40814 -17.74116 1.000 32.53283  ?  515 VAL A CA  1 
ATOM   3939 C  C   . VAL A 1 515 ? 31.11510  -30.62442 -17.24768 1.000 33.16503  ?  515 VAL A C   1 
ATOM   3940 O  O   . VAL A 1 515 ? 30.98100  -31.61990 -17.96675 1.000 38.68359  ?  515 VAL A O   1 
ATOM   3941 C  CB  . VAL A 1 515 ? 33.32501  -29.37571 -17.19817 1.000 34.01889  ?  515 VAL A CB  1 
ATOM   3942 C  CG1 . VAL A 1 515 ? 33.97042  -30.74854 -17.31053 1.000 33.34254  ?  515 VAL A CG1 1 
ATOM   3943 C  CG2 . VAL A 1 515 ? 34.13234  -28.34706 -17.96650 1.000 34.50387  ?  515 VAL A CG2 1 
ATOM   3944 N  N   . GLU A 1 516 ? 30.58254  -30.56668 -16.02372 1.000 30.36815  ?  516 GLU A N   1 
ATOM   3945 C  CA  . GLU A 1 516 ? 29.77863  -31.68631 -15.54450 1.000 30.32795  ?  516 GLU A CA  1 
ATOM   3946 C  C   . GLU A 1 516 ? 28.49872  -31.85093 -16.35510 1.000 28.28817  ?  516 GLU A C   1 
ATOM   3947 O  O   . GLU A 1 516 ? 27.99751  -32.97274 -16.49655 1.000 28.41944  ?  516 GLU A O   1 
ATOM   3948 C  CB  . GLU A 1 516 ? 29.45352  -31.51027 -14.06391 1.000 29.96126  ?  516 GLU A CB  1 
ATOM   3949 C  CG  . GLU A 1 516 ? 30.64789  -31.71005 -13.15315 1.000 30.68894  ?  516 GLU A CG  1 
ATOM   3950 C  CD  . GLU A 1 516 ? 30.27746  -31.63652 -11.68826 1.000 49.00528  ?  516 GLU A CD  1 
ATOM   3951 O  OE1 . GLU A 1 516 ? 29.07261  -31.50575 -11.38484 1.000 43.27462  ?  516 GLU A OE1 1 
ATOM   3952 O  OE2 . GLU A 1 516 ? 31.19060  -31.71018 -10.84029 1.000 70.70528  -1 516 GLU A OE2 1 
ATOM   3953 N  N   . GLY A 1 517 ? 27.95287  -30.75568 -16.88711 1.000 33.00031  ?  517 GLY A N   1 
ATOM   3954 C  CA  . GLY A 1 517 ? 26.75837  -30.85872 -17.70594 1.000 34.43848  ?  517 GLY A CA  1 
ATOM   3955 C  C   . GLY A 1 517 ? 27.00428  -31.40230 -19.09658 1.000 33.14524  ?  517 GLY A C   1 
ATOM   3956 O  O   . GLY A 1 517 ? 26.07561  -31.93166 -19.71687 1.000 34.13399  ?  517 GLY A O   1 
ATOM   3957 N  N   . LEU A 1 518 ? 28.23244  -31.28488 -19.60421 1.000 30.51562  ?  518 LEU A N   1 
ATOM   3958 C  CA  . LEU A 1 518 ? 28.53516  -31.75459 -20.94961 1.000 31.63608  ?  518 LEU A CA  1 
ATOM   3959 C  C   . LEU A 1 518 ? 29.36376  -33.03302 -20.99759 1.000 38.18913  ?  518 LEU A C   1 
ATOM   3960 O  O   . LEU A 1 518 ? 29.28167  -33.76179 -21.99237 1.000 35.68818  ?  518 LEU A O   1 
ATOM   3961 C  CB  . LEU A 1 518 ? 29.26444  -30.65825 -21.74052 1.000 35.89613  ?  518 LEU A CB  1 
ATOM   3962 C  CG  . LEU A 1 518 ? 28.44935  -29.38858 -22.00189 1.000 32.23589  ?  518 LEU A CG  1 
ATOM   3963 C  CD1 . LEU A 1 518 ? 29.35826  -28.23800 -22.39594 1.000 33.24195  ?  518 LEU A CD1 1 
ATOM   3964 C  CD2 . LEU A 1 518 ? 27.40374  -29.63206 -23.07830 1.000 29.10560  ?  518 LEU A CD2 1 
ATOM   3965 N  N   . LYS A 1 519 ? 30.14954  -33.32780 -19.95683 1.000 39.93027  ?  519 LYS A N   1 
ATOM   3966 C  CA  . LYS A 1 519 ? 31.05982  -34.47128 -19.94672 1.000 33.12644  ?  519 LYS A CA  1 
ATOM   3967 C  C   . LYS A 1 519 ? 30.35629  -35.69817 -19.37861 1.000 38.01647  ?  519 LYS A C   1 
ATOM   3968 O  O   . LYS A 1 519 ? 29.74056  -35.61002 -18.30939 1.000 35.57439  ?  519 LYS A O   1 
ATOM   3969 C  CB  . LYS A 1 519 ? 32.30504  -34.16671 -19.12396 1.000 37.62405  ?  519 LYS A CB  1 
ATOM   3970 C  CG  . LYS A 1 519 ? 33.48371  -35.08858 -19.39971 1.000 50.51041  ?  519 LYS A CG  1 
ATOM   3971 C  CD  . LYS A 1 519 ? 34.65823  -34.78423 -18.48009 1.000 51.94302  ?  519 LYS A CD  1 
ATOM   3972 C  CE  . LYS A 1 519 ? 34.57405  -35.57341 -17.18333 1.000 51.00005  ?  519 LYS A CE  1 
ATOM   3973 N  NZ  . LYS A 1 519 ? 34.91266  -37.00709 -17.39666 1.000 46.13426  ?  519 LYS A NZ  1 
ATOM   3974 N  N   . PRO A 1 520 ? 30.41800  -36.84148 -20.05728 1.000 40.91515  ?  520 PRO A N   1 
ATOM   3975 C  CA  . PRO A 1 520 ? 29.73727  -38.04008 -19.55529 1.000 39.08335  ?  520 PRO A CA  1 
ATOM   3976 C  C   . PRO A 1 520 ? 30.37234  -38.57342 -18.27914 1.000 46.98070  ?  520 PRO A C   1 
ATOM   3977 O  O   . PRO A 1 520 ? 31.54291  -38.33099 -17.97679 1.000 53.47743  ?  520 PRO A O   1 
ATOM   3978 C  CB  . PRO A 1 520 ? 29.88130  -39.04173 -20.70702 1.000 27.36966  ?  520 PRO A CB  1 
ATOM   3979 C  CG  . PRO A 1 520 ? 31.04838  -38.56381 -21.48449 1.000 28.37064  ?  520 PRO A CG  1 
ATOM   3980 C  CD  . PRO A 1 520 ? 31.05680  -37.07112 -21.36363 1.000 37.95467  ?  520 PRO A CD  1 
ATOM   3981 N  N   . HIS A 1 521 ? 29.56264  -39.30763 -17.52007 1.000 47.28212  ?  521 HIS A N   1 
ATOM   3982 C  CA  . HIS A 1 521 ? 30.01243  -39.93968 -16.28334 1.000 50.28084  ?  521 HIS A CA  1 
ATOM   3983 C  C   . HIS A 1 521 ? 29.46580  -41.35784 -16.16449 1.000 43.35488  ?  521 HIS A C   1 
ATOM   3984 O  O   . HIS A 1 521 ? 30.18240  -42.32971 -16.40229 1.000 45.93612  ?  521 HIS A O   1 
ATOM   3985 C  CB  . HIS A 1 521 ? 29.59110  -39.11137 -15.06778 1.000 60.87419  ?  521 HIS A CB  1 
ATOM   3986 C  CG  . HIS A 1 521 ? 30.40370  -37.86969 -14.87337 1.000 80.02506  ?  521 HIS A CG  1 
ATOM   3987 N  ND1 . HIS A 1 521 ? 31.53865  -37.83931 -14.09213 1.000 81.31258  ?  521 HIS A ND1 1 
ATOM   3988 C  CD2 . HIS A 1 521 ? 30.24942  -36.61605 -15.36155 1.000 73.76875  ?  521 HIS A CD2 1 
ATOM   3989 C  CE1 . HIS A 1 521 ? 32.04735  -36.62012 -14.10535 1.000 83.24435  ?  521 HIS A CE1 1 
ATOM   3990 N  NE2 . HIS A 1 521 ? 31.28419  -35.85856 -14.86847 1.000 71.17305  ?  521 HIS A NE2 1 
ATOM   3991 N  N   . LEU B 1 28  ? 54.29439  28.13563  -18.36898 1.000 71.06364  ?  28  LEU B N   1 
ATOM   3992 C  CA  . LEU B 1 28  ? 53.68316  29.45521  -18.47758 1.000 82.62658  ?  28  LEU B CA  1 
ATOM   3993 C  C   . LEU B 1 28  ? 52.16623  29.33174  -18.36823 1.000 73.33825  ?  28  LEU B C   1 
ATOM   3994 O  O   . LEU B 1 28  ? 51.65200  28.80882  -17.37846 1.000 65.12572  ?  28  LEU B O   1 
ATOM   3995 C  CB  . LEU B 1 28  ? 54.08158  30.12402  -19.79559 1.000 75.19524  ?  28  LEU B CB  1 
ATOM   3996 C  CG  . LEU B 1 28  ? 54.03196  31.65240  -19.84656 1.000 80.09405  ?  28  LEU B CG  1 
ATOM   3997 C  CD1 . LEU B 1 28  ? 54.89300  32.24627  -18.74493 1.000 70.61688  ?  28  LEU B CD1 1 
ATOM   3998 C  CD2 . LEU B 1 28  ? 54.47706  32.15405  -21.21033 1.000 86.36605  ?  28  LEU B CD2 1 
ATOM   3999 N  N   . THR B 1 29  ? 51.45094  29.81753  -19.38073 1.000 65.08433  ?  29  THR B N   1 
ATOM   4000 C  CA  . THR B 1 29  ? 50.01249  29.60508  -19.43413 1.000 55.74634  ?  29  THR B CA  1 
ATOM   4001 C  C   . THR B 1 29  ? 49.72978  28.11539  -19.55585 1.000 55.09545  ?  29  THR B C   1 
ATOM   4002 O  O   . THR B 1 29  ? 50.30243  27.43374  -20.41005 1.000 53.59405  ?  29  THR B O   1 
ATOM   4003 C  CB  . THR B 1 29  ? 49.40209  30.35874  -20.61713 1.000 53.06656  ?  29  THR B CB  1 
ATOM   4004 O  OG1 . THR B 1 29  ? 49.80581  31.73260  -20.57249 1.000 68.43863  ?  29  THR B OG1 1 
ATOM   4005 C  CG2 . THR B 1 29  ? 47.88173  30.28270  -20.57283 1.000 44.19785  ?  29  THR B CG2 1 
ATOM   4006 N  N   . SER B 1 30  ? 48.85617  27.60472  -18.68578 1.000 56.02989  ?  30  SER B N   1 
ATOM   4007 C  CA  . SER B 1 30  ? 48.51729  26.18710  -18.74419 1.000 46.25748  ?  30  SER B CA  1 
ATOM   4008 C  C   . SER B 1 30  ? 47.87291  25.84016  -20.07872 1.000 31.85057  ?  30  SER B C   1 
ATOM   4009 O  O   . SER B 1 30  ? 48.17343  24.79722  -20.67238 1.000 31.31026  ?  30  SER B O   1 
ATOM   4010 C  CB  . SER B 1 30  ? 47.59676  25.81736  -17.58152 1.000 38.91201  ?  30  SER B CB  1 
ATOM   4011 O  OG  . SER B 1 30  ? 48.24954  26.00684  -16.33763 1.000 40.60476  ?  30  SER B OG  1 
ATOM   4012 N  N   . LYS B 1 31  ? 46.99635  26.71573  -20.57259 1.000 25.99061  ?  31  LYS B N   1 
ATOM   4013 C  CA  . LYS B 1 31  ? 46.37866  26.50384  -21.87629 1.000 26.44520  ?  31  LYS B CA  1 
ATOM   4014 C  C   . LYS B 1 31  ? 47.42895  26.47788  -22.98180 1.000 31.67089  ?  31  LYS B C   1 
ATOM   4015 O  O   . LYS B 1 31  ? 47.42592  25.58452  -23.83534 1.000 33.64234  ?  31  LYS B O   1 
ATOM   4016 C  CB  . LYS B 1 31  ? 45.33794  27.59628  -22.12917 1.000 25.01015  ?  31  LYS B CB  1 
ATOM   4017 C  CG  . LYS B 1 31  ? 44.44393  27.37875  -23.33595 1.000 18.60249  ?  31  LYS B CG  1 
ATOM   4018 C  CD  . LYS B 1 31  ? 43.35347  28.43944  -23.37857 1.000 20.46558  ?  31  LYS B CD  1 
ATOM   4019 C  CE  . LYS B 1 31  ? 42.48001  28.30707  -24.61343 1.000 30.34159  ?  31  LYS B CE  1 
ATOM   4020 N  NZ  . LYS B 1 31  ? 41.39158  29.32451  -24.62252 1.000 23.74568  ?  31  LYS B NZ  1 
ATOM   4021 N  N   . ALA B 1 32  ? 48.35885  27.43736  -22.96365 1.000 40.33849  ?  32  ALA B N   1 
ATOM   4022 C  CA  . ALA B 1 32  ? 49.37110  27.50982  -24.01524 1.000 39.94554  ?  32  ALA B CA  1 
ATOM   4023 C  C   . ALA B 1 32  ? 50.34896  26.34050  -23.94038 1.000 37.79755  ?  32  ALA B C   1 
ATOM   4024 O  O   . ALA B 1 32  ? 50.75557  25.79879  -24.97475 1.000 41.61814  ?  32  ALA B O   1 
ATOM   4025 C  CB  . ALA B 1 32  ? 50.11678  28.84129  -23.93450 1.000 28.71164  ?  32  ALA B CB  1 
ATOM   4026 N  N   . ALA B 1 33  ? 50.75024  25.94508  -22.72955 1.000 32.00051  ?  33  ALA B N   1 
ATOM   4027 C  CA  . ALA B 1 33  ? 51.63861  24.79501  -22.58467 1.000 31.79233  ?  33  ALA B CA  1 
ATOM   4028 C  C   . ALA B 1 33  ? 50.95733  23.51472  -23.04998 1.000 34.65040  ?  33  ALA B C   1 
ATOM   4029 O  O   . ALA B 1 33  ? 51.57743  22.67076  -23.71472 1.000 35.42415  ?  33  ALA B O   1 
ATOM   4030 C  CB  . ALA B 1 33  ? 52.09490  24.66518  -21.13185 1.000 33.01330  ?  33  ALA B CB  1 
ATOM   4031 N  N   . TYR B 1 34  ? 49.67674  23.35383  -22.70818 1.000 40.02369  ?  34  TYR B N   1 
ATOM   4032 C  CA  . TYR B 1 34  ? 48.91709  22.21707  -23.21075 1.000 36.08829  ?  34  TYR B CA  1 
ATOM   4033 C  C   . TYR B 1 34  ? 48.84555  22.24181  -24.73064 1.000 36.47790  ?  34  TYR B C   1 
ATOM   4034 O  O   . TYR B 1 34  ? 48.92802  21.19345  -25.37627 1.000 37.69919  ?  34  TYR B O   1 
ATOM   4035 C  CB  . TYR B 1 34  ? 47.51285  22.21275  -22.60354 1.000 34.98393  ?  34  TYR B CB  1 
ATOM   4036 C  CG  . TYR B 1 34  ? 46.60036  21.14249  -23.16293 1.000 31.59901  ?  34  TYR B CG  1 
ATOM   4037 C  CD1 . TYR B 1 34  ? 45.86433  21.36450  -24.32125 1.000 30.02835  ?  34  TYR B CD1 1 
ATOM   4038 C  CD2 . TYR B 1 34  ? 46.46873  19.91438  -22.52981 1.000 23.59428  ?  34  TYR B CD2 1 
ATOM   4039 C  CE1 . TYR B 1 34  ? 45.03783  20.39446  -24.83833 1.000 26.32645  ?  34  TYR B CE1 1 
ATOM   4040 C  CE2 . TYR B 1 34  ? 45.63640  18.93889  -23.03731 1.000 21.41387  ?  34  TYR B CE2 1 
ATOM   4041 C  CZ  . TYR B 1 34  ? 44.92372  19.18590  -24.19160 1.000 24.94404  ?  34  TYR B CZ  1 
ATOM   4042 O  OH  . TYR B 1 34  ? 44.09290  18.22141  -24.70562 1.000 27.13110  ?  34  TYR B OH  1 
ATOM   4043 N  N   . LEU B 1 35  ? 48.67268  23.42847  -25.31933 1.000 28.63261  ?  35  LEU B N   1 
ATOM   4044 C  CA  . LEU B 1 35  ? 48.63713  23.52928  -26.77543 1.000 32.28768  ?  35  LEU B CA  1 
ATOM   4045 C  C   . LEU B 1 35  ? 49.97556  23.13763  -27.38758 1.000 34.79479  ?  35  LEU B C   1 
ATOM   4046 O  O   . LEU B 1 35  ? 50.01991  22.49542  -28.44319 1.000 39.04134  ?  35  LEU B O   1 
ATOM   4047 C  CB  . LEU B 1 35  ? 48.24727  24.94485  -27.20101 1.000 35.17822  ?  35  LEU B CB  1 
ATOM   4048 C  CG  . LEU B 1 35  ? 46.82081  25.39210  -26.87417 1.000 34.53942  ?  35  LEU B CG  1 
ATOM   4049 C  CD1 . LEU B 1 35  ? 46.50685  26.72989  -27.52905 1.000 28.40495  ?  35  LEU B CD1 1 
ATOM   4050 C  CD2 . LEU B 1 35  ? 45.80925  24.33198  -27.28309 1.000 38.62354  ?  35  LEU B CD2 1 
ATOM   4051 N  N   . LEU B 1 36  ? 51.07764  23.53195  -26.74723 1.000 36.94472  ?  36  LEU B N   1 
ATOM   4052 C  CA  . LEU B 1 36  ? 52.39773  23.13113  -27.22638 1.000 40.56455  ?  36  LEU B CA  1 
ATOM   4053 C  C   . LEU B 1 36  ? 52.54511  21.61453  -27.20446 1.000 35.90683  ?  36  LEU B C   1 
ATOM   4054 O  O   . LEU B 1 36  ? 52.98910  21.00499  -28.18721 1.000 27.10824  ?  36  LEU B O   1 
ATOM   4055 C  CB  . LEU B 1 36  ? 53.48839  23.79104  -26.38039 1.000 35.54361  ?  36  LEU B CB  1 
ATOM   4056 C  CG  . LEU B 1 36  ? 53.63728  25.31016  -26.48861 1.000 28.12224  ?  36  LEU B CG  1 
ATOM   4057 C  CD1 . LEU B 1 36  ? 54.72303  25.80910  -25.54795 1.000 30.00050  ?  36  LEU B CD1 1 
ATOM   4058 C  CD2 . LEU B 1 36  ? 53.93521  25.72275  -27.92232 1.000 25.59166  ?  36  LEU B CD2 1 
ATOM   4059 N  N   . LYS B 1 37  ? 52.15466  20.98702  -26.09018 1.000 39.06652  ?  37  LYS B N   1 
ATOM   4060 C  CA  . LYS B 1 37  ? 52.20974  19.52873  -26.00315 1.000 38.93122  ?  37  LYS B CA  1 
ATOM   4061 C  C   . LYS B 1 37  ? 51.31697  18.87943  -27.05575 1.000 39.90842  ?  37  LYS B C   1 
ATOM   4062 O  O   . LYS B 1 37  ? 51.70593  17.89130  -27.69143 1.000 38.86862  ?  37  LYS B O   1 
ATOM   4063 C  CB  . LYS B 1 37  ? 51.80430  19.06776  -24.60174 1.000 29.80075  ?  37  LYS B CB  1 
ATOM   4064 C  CG  . LYS B 1 37  ? 52.89480  19.19547  -23.54626 1.000 34.10363  ?  37  LYS B CG  1 
ATOM   4065 C  CD  . LYS B 1 37  ? 53.97557  18.14014  -23.73477 1.000 48.28184  ?  37  LYS B CD  1 
ATOM   4066 C  CE  . LYS B 1 37  ? 55.00096  18.18219  -22.60926 1.000 38.51336  ?  37  LYS B CE  1 
ATOM   4067 N  NZ  . LYS B 1 37  ? 54.39511  17.87251  -21.28386 1.000 27.18953  ?  37  LYS B NZ  1 
ATOM   4068 N  N   . ARG B 1 38  ? 50.11996  19.43318  -27.25963 1.000 32.26641  ?  38  ARG B N   1 
ATOM   4069 C  CA  . ARG B 1 38  ? 49.16744  18.86413  -28.20623 1.000 28.97855  ?  38  ARG B CA  1 
ATOM   4070 C  C   . ARG B 1 38  ? 49.69654  18.92991  -29.63106 1.000 29.43805  ?  38  ARG B C   1 
ATOM   4071 O  O   . ARG B 1 38  ? 49.62822  17.94721  -30.37679 1.000 30.83257  ?  38  ARG B O   1 
ATOM   4072 C  CB  . ARG B 1 38  ? 47.83118  19.59942  -28.09291 1.000 25.07972  ?  38  ARG B CB  1 
ATOM   4073 C  CG  . ARG B 1 38  ? 46.74598  19.09324  -29.02503 1.000 23.16511  ?  38  ARG B CG  1 
ATOM   4074 C  CD  . ARG B 1 38  ? 45.53048  20.00951  -28.98852 1.000 24.54098  ?  38  ARG B CD  1 
ATOM   4075 N  NE  . ARG B 1 38  ? 44.34567  19.37506  -29.55418 1.000 24.10393  ?  38  ARG B NE  1 
ATOM   4076 C  CZ  . ARG B 1 38  ? 43.92387  19.53517  -30.80092 1.000 23.71986  ?  38  ARG B CZ  1 
ATOM   4077 N  NH1 . ARG B 1 38  ? 44.56506  20.31771  -31.65345 1.000 23.05733  ?  38  ARG B NH1 1 
ATOM   4078 N  NH2 . ARG B 1 38  ? 42.82921  18.89481  -31.20181 1.000 21.42225  ?  38  ARG B NH2 1 
ATOM   4079 N  N   . ASN B 1 39  ? 50.22342  20.08747  -30.03102 1.000 34.89530  ?  39  ASN B N   1 
ATOM   4080 C  CA  . ASN B 1 39  ? 50.74488  20.22005  -31.38490 1.000 37.87316  ?  39  ASN B CA  1 
ATOM   4081 C  C   . ASN B 1 39  ? 52.00571  19.39097  -31.58626 1.000 34.31104  ?  39  ASN B C   1 
ATOM   4082 O  O   . ASN B 1 39  ? 52.20240  18.83388  -32.67202 1.000 31.88377  ?  39  ASN B O   1 
ATOM   4083 C  CB  . ASN B 1 39  ? 50.99454  21.69131  -31.70955 1.000 37.80835  ?  39  ASN B CB  1 
ATOM   4084 C  CG  . ASN B 1 39  ? 49.71955  22.42335  -32.07748 1.000 42.54728  ?  39  ASN B CG  1 
ATOM   4085 O  OD1 . ASN B 1 39  ? 48.90076  21.91536  -32.84486 1.000 34.06462  ?  39  ASN B OD1 1 
ATOM   4086 N  ND2 . ASN B 1 39  ? 49.53498  23.61319  -31.51947 1.000 53.15545  ?  39  ASN B ND2 1 
ATOM   4087 N  N   . SER B 1 40  ? 52.85430  19.27080  -30.55918 1.000 34.46720  ?  40  SER B N   1 
ATOM   4088 C  CA  . SER B 1 40  ? 53.99561  18.36669  -30.66266 1.000 37.99341  ?  40  SER B CA  1 
ATOM   4089 C  C   . SER B 1 40  ? 53.53490  16.92936  -30.87385 1.000 42.94206  ?  40  SER B C   1 
ATOM   4090 O  O   . SER B 1 40  ? 54.06847  16.21780  -31.73383 1.000 40.35603  ?  40  SER B O   1 
ATOM   4091 C  CB  . SER B 1 40  ? 54.86836  18.47671  -29.41077 1.000 38.54375  ?  40  SER B CB  1 
ATOM   4092 O  OG  . SER B 1 40  ? 55.96602  17.58240  -29.46454 1.000 46.86995  ?  40  SER B OG  1 
ATOM   4093 N  N   . LEU B 1 41  ? 52.52483  16.49402  -30.11438 1.000 39.60954  ?  41  LEU B N   1 
ATOM   4094 C  CA  . LEU B 1 41  ? 52.01565  15.13304  -30.25863 1.000 35.77788  ?  41  LEU B CA  1 
ATOM   4095 C  C   . LEU B 1 41  ? 51.39553  14.91006  -31.63348 1.000 29.47226  ?  41  LEU B C   1 
ATOM   4096 O  O   . LEU B 1 41  ? 51.58753  13.85283  -32.24562 1.000 28.84981  ?  41  LEU B O   1 
ATOM   4097 C  CB  . LEU B 1 41  ? 50.99555  14.83983  -29.15871 1.000 23.26603  ?  41  LEU B CB  1 
ATOM   4098 C  CG  . LEU B 1 41  ? 50.31476  13.47173  -29.20430 1.000 15.97233  ?  41  LEU B CG  1 
ATOM   4099 C  CD1 . LEU B 1 41  ? 51.33008  12.35775  -29.00113 1.000 22.95315  ?  41  LEU B CD1 1 
ATOM   4100 C  CD2 . LEU B 1 41  ? 49.20047  13.38589  -28.17123 1.000 14.96125  ?  41  LEU B CD2 1 
ATOM   4101 N  N   . ILE B 1 42  ? 50.64262  15.89188  -32.13306 1.000 28.58118  ?  42  ILE B N   1 
ATOM   4102 C  CA  . ILE B 1 42  ? 49.98025  15.73244  -33.42429 1.000 23.16606  ?  42  ILE B CA  1 
ATOM   4103 C  C   . ILE B 1 42  ? 51.00165  15.71678  -34.55613 1.000 32.24671  ?  42  ILE B C   1 
ATOM   4104 O  O   . ILE B 1 42  ? 50.87568  14.93791  -35.50801 1.000 31.13874  ?  42  ILE B O   1 
ATOM   4105 C  CB  . ILE B 1 42  ? 48.91735  16.82845  -33.62256 1.000 20.09015  ?  42  ILE B CB  1 
ATOM   4106 C  CG1 . ILE B 1 42  ? 47.78052  16.64908  -32.61451 1.000 19.75437  ?  42  ILE B CG1 1 
ATOM   4107 C  CG2 . ILE B 1 42  ? 48.36693  16.79397  -35.03806 1.000 18.10206  ?  42  ILE B CG2 1 
ATOM   4108 C  CD1 . ILE B 1 42  ? 46.65075  17.64237  -32.77942 1.000 18.30613  ?  42  ILE B CD1 1 
ATOM   4109 N  N   . GLU B 1 43  ? 52.02907  16.56833  -34.47635 1.000 39.82210  ?  43  GLU B N   1 
ATOM   4110 C  CA  . GLU B 1 43  ? 53.10257  16.51680  -35.46440 1.000 37.97415  ?  43  GLU B CA  1 
ATOM   4111 C  C   . GLU B 1 43  ? 53.83447  15.18167  -35.40793 1.000 40.01903  ?  43  GLU B C   1 
ATOM   4112 O  O   . GLU B 1 43  ? 54.18839  14.61378  -36.44815 1.000 38.37566  ?  43  GLU B O   1 
ATOM   4113 C  CB  . GLU B 1 43  ? 54.07901  17.67306  -35.24553 1.000 41.76229  ?  43  GLU B CB  1 
ATOM   4114 C  CG  . GLU B 1 43  ? 53.55309  19.03471  -35.67302 1.000 57.56148  ?  43  GLU B CG  1 
ATOM   4115 C  CD  . GLU B 1 43  ? 54.50885  20.16274  -35.32523 1.000 70.56236  ?  43  GLU B CD  1 
ATOM   4116 O  OE1 . GLU B 1 43  ? 55.19650  20.06161  -34.28723 1.000 64.17592  ?  43  GLU B OE1 1 
ATOM   4117 O  OE2 . GLU B 1 43  ? 54.57744  21.14769  -36.09136 1.000 57.70857  -1 43  GLU B OE2 1 
ATOM   4118 N  N   . GLU B 1 44  ? 54.07065  14.66611  -34.19823 1.000 37.86707  ?  44  GLU B N   1 
ATOM   4119 C  CA  . GLU B 1 44  ? 54.73619  13.37603  -34.05054 1.000 37.44957  ?  44  GLU B CA  1 
ATOM   4120 C  C   . GLU B 1 44  ? 53.91123  12.25030  -34.66414 1.000 34.51147  ?  44  GLU B C   1 
ATOM   4121 O  O   . GLU B 1 44  ? 54.45873  11.34798  -35.30874 1.000 25.79900  ?  44  GLU B O   1 
ATOM   4122 C  CB  . GLU B 1 44  ? 55.00102  13.10770  -32.56909 1.000 37.69057  ?  44  GLU B CB  1 
ATOM   4123 C  CG  . GLU B 1 44  ? 55.67354  11.78391  -32.26408 1.000 40.87347  ?  44  GLU B CG  1 
ATOM   4124 C  CD  . GLU B 1 44  ? 55.79670  11.53853  -30.77227 1.000 54.79278  ?  44  GLU B CD  1 
ATOM   4125 O  OE1 . GLU B 1 44  ? 55.34125  12.39985  -29.98874 1.000 44.22242  ?  44  GLU B OE1 1 
ATOM   4126 O  OE2 . GLU B 1 44  ? 56.34632  10.48694  -30.38263 1.000 63.20889  -1 44  GLU B OE2 1 
ATOM   4127 N  N   . ASP B 1 45  ? 52.59148  12.28319  -34.46692 1.000 37.83650  ?  45  ASP B N   1 
ATOM   4128 C  CA  . ASP B 1 45  ? 51.73621  11.21633  -34.97941 1.000 29.06704  ?  45  ASP B CA  1 
ATOM   4129 C  C   . ASP B 1 45  ? 51.55731  11.31573  -36.49092 1.000 29.14820  ?  45  ASP B C   1 
ATOM   4130 O  O   . ASP B 1 45  ? 51.60123  10.29925  -37.19452 1.000 24.60670  ?  45  ASP B O   1 
ATOM   4131 C  CB  . ASP B 1 45  ? 50.38024  11.25191  -34.27366 1.000 22.79291  ?  45  ASP B CB  1 
ATOM   4132 C  CG  . ASP B 1 45  ? 49.41116  10.21949  -34.81658 1.000 21.54368  ?  45  ASP B CG  1 
ATOM   4133 O  OD1 . ASP B 1 45  ? 49.60581  9.01656   -34.54438 1.000 21.01674  ?  45  ASP B OD1 1 
ATOM   4134 O  OD2 . ASP B 1 45  ? 48.45220  10.61190  -35.51443 1.000 17.74345  -1 45  ASP B OD2 1 
ATOM   4135 N  N   . ALA B 1 46  ? 51.35721  12.52812  -37.00953 1.000 26.87050  ?  46  ALA B N   1 
ATOM   4136 C  CA  . ALA B 1 46  ? 51.07813  12.71963  -38.42664 1.000 24.23778  ?  46  ALA B CA  1 
ATOM   4137 C  C   . ALA B 1 46  ? 52.31635  12.59857  -39.30419 1.000 27.85472  ?  46  ALA B C   1 
ATOM   4138 O  O   . ALA B 1 46  ? 52.18200  12.57317  -40.53252 1.000 25.69263  ?  46  ALA B O   1 
ATOM   4139 C  CB  . ALA B 1 46  ? 50.41996  14.08253  -38.65270 1.000 20.80579  ?  46  ALA B CB  1 
ATOM   4140 N  N   . SER B 1 47  ? 53.51012  12.53313  -38.71456 1.000 29.21813  ?  47  SER B N   1 
ATOM   4141 C  CA  . SER B 1 47  ? 54.72370  12.30693  -39.48740 1.000 24.43868  ?  47  SER B CA  1 
ATOM   4142 C  C   . SER B 1 47  ? 54.92968  10.84026  -39.83642 1.000 23.11246  ?  47  SER B C   1 
ATOM   4143 O  O   . SER B 1 47  ? 55.79281  10.53077  -40.66467 1.000 22.52044  ?  47  SER B O   1 
ATOM   4144 C  CB  . SER B 1 47  ? 55.94225  12.82483  -38.72080 1.000 26.46665  ?  47  SER B CB  1 
ATOM   4145 O  OG  . SER B 1 47  ? 56.15116  12.07453  -37.53788 1.000 30.19629  ?  47  SER B OG  1 
ATOM   4146 N  N   . ARG B 1 48  ? 54.16037  9.93757   -39.22991 1.000 28.78411  ?  48  ARG B N   1 
ATOM   4147 C  CA  . ARG B 1 48  ? 54.27414  8.51245   -39.50425 1.000 32.00582  ?  48  ARG B CA  1 
ATOM   4148 C  C   . ARG B 1 48  ? 53.55945  8.09561   -40.78162 1.000 28.30895  ?  48  ARG B C   1 
ATOM   4149 O  O   . ARG B 1 48  ? 53.75433  6.96441   -41.23741 1.000 27.75680  ?  48  ARG B O   1 
ATOM   4150 C  CB  . ARG B 1 48  ? 53.71584  7.71109   -38.32553 1.000 27.99324  ?  48  ARG B CB  1 
ATOM   4151 C  CG  . ARG B 1 48  ? 54.30304  8.09840   -36.97883 1.000 30.23746  ?  48  ARG B CG  1 
ATOM   4152 C  CD  . ARG B 1 48  ? 55.60268  7.36585   -36.71077 1.000 22.58236  ?  48  ARG B CD  1 
ATOM   4153 N  NE  . ARG B 1 48  ? 55.38491  5.93273   -36.55875 1.000 24.28556  ?  48  ARG B NE  1 
ATOM   4154 C  CZ  . ARG B 1 48  ? 55.06313  5.34220   -35.41592 1.000 25.23546  ?  48  ARG B CZ  1 
ATOM   4155 N  NH1 . ARG B 1 48  ? 54.91514  6.03423   -34.29797 1.000 21.92871  ?  48  ARG B NH1 1 
ATOM   4156 N  NH2 . ARG B 1 48  ? 54.88490  4.02428   -35.39418 1.000 31.38797  ?  48  ARG B NH2 1 
ATOM   4157 N  N   . LYS B 1 49  ? 52.74771  8.97209   -41.36636 1.000 23.05609  ?  49  LYS B N   1 
ATOM   4158 C  CA  . LYS B 1 49  ? 51.96339  8.60612   -42.53356 1.000 20.31293  ?  49  LYS B CA  1 
ATOM   4159 C  C   . LYS B 1 49  ? 52.85928  8.42843   -43.75576 1.000 22.62247  ?  49  LYS B C   1 
ATOM   4160 O  O   . LYS B 1 49  ? 53.98150  8.93869   -43.82260 1.000 26.59813  ?  49  LYS B O   1 
ATOM   4161 C  CB  . LYS B 1 49  ? 50.89614  9.66297   -42.81796 1.000 20.49254  ?  49  LYS B CB  1 
ATOM   4162 C  CG  . LYS B 1 49  ? 51.44467  10.94674  -43.41252 1.000 20.27268  ?  49  LYS B CG  1 
ATOM   4163 C  CD  . LYS B 1 49  ? 50.34556  11.96660  -43.65338 1.000 19.36284  ?  49  LYS B CD  1 
ATOM   4164 C  CE  . LYS B 1 49  ? 50.88619  13.17707  -44.39622 1.000 26.38149  ?  49  LYS B CE  1 
ATOM   4165 N  NZ  . LYS B 1 49  ? 49.88906  14.27755  -44.48681 1.000 26.75860  ?  49  LYS B NZ  1 
ATOM   4166 N  N   . LEU B 1 50  ? 52.34774  7.67344   -44.72533 1.000 23.56401  ?  50  LEU B N   1 
ATOM   4167 C  CA  . LEU B 1 50  ? 53.04756  7.49416   -45.98894 1.000 23.98302  ?  50  LEU B CA  1 
ATOM   4168 C  C   . LEU B 1 50  ? 53.17428  8.82858   -46.71238 1.000 27.56104  ?  50  LEU B C   1 
ATOM   4169 O  O   . LEU B 1 50  ? 52.20124  9.57906   -46.83365 1.000 23.05334  ?  50  LEU B O   1 
ATOM   4170 C  CB  . LEU B 1 50  ? 52.30087  6.48589   -46.86300 1.000 20.45448  ?  50  LEU B CB  1 
ATOM   4171 C  CG  . LEU B 1 50  ? 52.85159  6.24923   -48.27121 1.000 23.54860  ?  50  LEU B CG  1 
ATOM   4172 C  CD1 . LEU B 1 50  ? 54.04155  5.29966   -48.24034 1.000 26.57496  ?  50  LEU B CD1 1 
ATOM   4173 C  CD2 . LEU B 1 50  ? 51.76253  5.73081   -49.19859 1.000 20.57172  ?  50  LEU B CD2 1 
ATOM   4174 N  N   . GLY B 1 51  ? 54.37952  9.12379   -47.19231 1.000 28.15225  ?  51  GLY B N   1 
ATOM   4175 C  CA  . GLY B 1 51  ? 54.61472  10.35039  -47.92350 1.000 28.00414  ?  51  GLY B CA  1 
ATOM   4176 C  C   . GLY B 1 51  ? 54.81434  11.58547  -47.07821 1.000 29.29945  ?  51  GLY B C   1 
ATOM   4177 O  O   . GLY B 1 51  ? 54.87320  12.68864  -47.63243 1.000 35.73624  ?  51  GLY B O   1 
ATOM   4178 N  N   . ALA B 1 52  ? 54.91676  11.44233  -45.75467 1.000 26.03930  ?  52  ALA B N   1 
ATOM   4179 C  CA  . ALA B 1 52  ? 55.11967  12.60823  -44.90103 1.000 27.99758  ?  52  ALA B CA  1 
ATOM   4180 C  C   . ALA B 1 52  ? 56.45227  13.28984  -45.18425 1.000 33.18615  ?  52  ALA B C   1 
ATOM   4181 O  O   . ALA B 1 52  ? 56.58886  14.49959  -44.96805 1.000 28.09858  ?  52  ALA B O   1 
ATOM   4182 C  CB  . ALA B 1 52  ? 55.03082  12.20372  -43.42980 1.000 27.16525  ?  52  ALA B CB  1 
ATOM   4183 N  N   . LYS B 1 53  ? 57.43883  12.53929  -45.67181 1.000 37.39900  ?  53  LYS B N   1 
ATOM   4184 C  CA  . LYS B 1 53  ? 58.75813  13.08556  -45.96288 1.000 34.42244  ?  53  LYS B CA  1 
ATOM   4185 C  C   . LYS B 1 53  ? 58.84291  13.73556  -47.33855 1.000 39.67190  ?  53  LYS B C   1 
ATOM   4186 O  O   . LYS B 1 53  ? 59.90002  14.27503  -47.68507 1.000 37.97970  ?  53  LYS B O   1 
ATOM   4187 C  CB  . LYS B 1 53  ? 59.81615  11.98520  -45.83803 1.000 25.45567  ?  53  LYS B CB  1 
ATOM   4188 C  CG  . LYS B 1 53  ? 59.86062  11.33427  -44.46159 1.000 33.28392  ?  53  LYS B CG  1 
ATOM   4189 C  CD  . LYS B 1 53  ? 60.81817  10.15291  -44.42372 1.000 53.93785  ?  53  LYS B CD  1 
ATOM   4190 C  CE  . LYS B 1 53  ? 60.75672  9.43794   -43.08087 1.000 51.66791  ?  53  LYS B CE  1 
ATOM   4191 N  NZ  . LYS B 1 53  ? 61.65342  8.24847   -43.03594 1.000 44.48303  ?  53  LYS B NZ  1 
ATOM   4192 N  N   . ILE B 1 54  ? 57.76761  13.69582  -48.12646 1.000 36.86849  ?  54  ILE B N   1 
ATOM   4193 C  CA  . ILE B 1 54  ? 57.75301  14.37807  -49.41439 1.000 30.37100  ?  54  ILE B CA  1 
ATOM   4194 C  C   . ILE B 1 54  ? 57.84454  15.88006  -49.19002 1.000 38.87772  ?  54  ILE B C   1 
ATOM   4195 O  O   . ILE B 1 54  ? 57.08519  16.45474  -48.39870 1.000 36.48374  ?  54  ILE B O   1 
ATOM   4196 C  CB  . ILE B 1 54  ? 56.48705  14.01452  -50.20495 1.000 26.58610  ?  54  ILE B CB  1 
ATOM   4197 C  CG1 . ILE B 1 54  ? 56.60318  12.61256  -50.80471 1.000 27.06900  ?  54  ILE B CG1 1 
ATOM   4198 C  CG2 . ILE B 1 54  ? 56.22106  15.04046  -51.29882 1.000 25.36331  ?  54  ILE B CG2 1 
ATOM   4199 C  CD1 . ILE B 1 54  ? 57.55480  12.52522  -51.97662 1.000 22.06578  ?  54  ILE B CD1 1 
ATOM   4200 N  N   . VAL B 1 55  ? 58.77784  16.52332  -49.88579 1.000 46.54566  ?  55  VAL B N   1 
ATOM   4201 C  CA  . VAL B 1 55  ? 58.92557  17.97322  -49.86778 1.000 36.33802  ?  55  VAL B CA  1 
ATOM   4202 C  C   . VAL B 1 55  ? 58.42776  18.51335  -51.20010 1.000 30.54618  ?  55  VAL B C   1 
ATOM   4203 O  O   . VAL B 1 55  ? 58.87791  18.07365  -52.26548 1.000 34.34773  ?  55  VAL B O   1 
ATOM   4204 C  CB  . VAL B 1 55  ? 60.38151  18.39280  -49.60111 1.000 29.89842  ?  55  VAL B CB  1 
ATOM   4205 C  CG1 . VAL B 1 55  ? 60.69373  18.28625  -48.11843 1.000 30.58824  ?  55  VAL B CG1 1 
ATOM   4206 C  CG2 . VAL B 1 55  ? 61.34311  17.53022  -50.40597 1.000 33.02599  ?  55  VAL B CG2 1 
ATOM   4207 N  N   . LEU B 1 56  ? 57.49503  19.45679  -51.14071 1.000 22.78106  ?  56  LEU B N   1 
ATOM   4208 C  CA  . LEU B 1 56  ? 56.85785  20.00080  -52.33063 1.000 27.48387  ?  56  LEU B CA  1 
ATOM   4209 C  C   . LEU B 1 56  ? 57.45002  21.36276  -52.66072 1.000 28.91513  ?  56  LEU B C   1 
ATOM   4210 O  O   . LEU B 1 56  ? 57.62451  22.20165  -51.77084 1.000 27.35397  ?  56  LEU B O   1 
ATOM   4211 C  CB  . LEU B 1 56  ? 55.34588  20.12569  -52.13354 1.000 25.70418  ?  56  LEU B CB  1 
ATOM   4212 C  CG  . LEU B 1 56  ? 54.53734  18.83741  -51.97590 1.000 25.58299  ?  56  LEU B CG  1 
ATOM   4213 C  CD1 . LEU B 1 56  ? 53.05780  19.15724  -51.82215 1.000 23.30319  ?  56  LEU B CD1 1 
ATOM   4214 C  CD2 . LEU B 1 56  ? 54.76696  17.90858  -53.15610 1.000 25.20901  ?  56  LEU B CD2 1 
ATOM   4215 N  N   . THR B 1 57  ? 57.76009  21.57632  -53.93692 1.000 28.09241  ?  57  THR B N   1 
ATOM   4216 C  CA  . THR B 1 57  ? 58.08762  22.91266  -54.40150 1.000 32.22790  ?  57  THR B CA  1 
ATOM   4217 C  C   . THR B 1 57  ? 56.85820  23.81257  -54.27752 1.000 35.19078  ?  57  THR B C   1 
ATOM   4218 O  O   . THR B 1 57  ? 55.74305  23.35201  -54.02297 1.000 37.52196  ?  57  THR B O   1 
ATOM   4219 C  CB  . THR B 1 57  ? 58.58960  22.87357  -55.84533 1.000 31.81803  ?  57  THR B CB  1 
ATOM   4220 O  OG1 . THR B 1 57  ? 57.57665  22.31882  -56.69439 1.000 23.42423  ?  57  THR B OG1 1 
ATOM   4221 C  CG2 . THR B 1 57  ? 59.84783  22.02293  -55.94643 1.000 25.55652  ?  57  THR B CG2 1 
ATOM   4222 N  N   . ASN B 1 58  ? 57.07005  25.11796  -54.45733 1.000 26.92335  ?  58  ASN B N   1 
ATOM   4223 C  CA  . ASN B 1 58  ? 55.98098  26.07025  -54.25447 1.000 31.28719  ?  58  ASN B CA  1 
ATOM   4224 C  C   . ASN B 1 58  ? 54.82593  25.80832  -55.21610 1.000 36.75790  ?  58  ASN B C   1 
ATOM   4225 O  O   . ASN B 1 58  ? 53.65393  25.92598  -54.83891 1.000 35.79574  ?  58  ASN B O   1 
ATOM   4226 C  CB  . ASN B 1 58  ? 56.50034  27.50008  -54.40265 1.000 32.68449  ?  58  ASN B CB  1 
ATOM   4227 C  CG  . ASN B 1 58  ? 57.44253  27.89745  -53.28029 1.000 34.29935  ?  58  ASN B CG  1 
ATOM   4228 O  OD1 . ASN B 1 58  ? 58.01848  27.04479  -52.60322 1.000 30.13662  ?  58  ASN B OD1 1 
ATOM   4229 N  ND2 . ASN B 1 58  ? 57.60150  29.19994  -53.07636 1.000 51.60990  ?  58  ASN B ND2 1 
ATOM   4230 N  N   . GLU B 1 59  ? 55.13765  25.45353  -56.46385 1.000 30.63571  ?  59  GLU B N   1 
ATOM   4231 C  CA  . GLU B 1 59  ? 54.09527  25.10692  -57.42564 1.000 28.54978  ?  59  GLU B CA  1 
ATOM   4232 C  C   . GLU B 1 59  ? 53.34575  23.84930  -56.99537 1.000 31.21609  ?  59  GLU B C   1 
ATOM   4233 O  O   . GLU B 1 59  ? 52.10720  23.78408  -57.07472 1.000 39.80771  ?  59  GLU B O   1 
ATOM   4234 C  CB  . GLU B 1 59  ? 54.71791  24.92114  -58.81047 1.000 25.17297  ?  59  GLU B CB  1 
ATOM   4235 C  CG  . GLU B 1 59  ? 55.55575  26.10350  -59.29243 1.000 41.46029  ?  59  GLU B CG  1 
ATOM   4236 C  CD  . GLU B 1 59  ? 56.95947  26.11408  -58.70830 1.000 52.35869  ?  59  GLU B CD  1 
ATOM   4237 O  OE1 . GLU B 1 59  ? 57.40598  25.05759  -58.21223 1.000 47.67626  ?  59  GLU B OE1 1 
ATOM   4238 O  OE2 . GLU B 1 59  ? 57.61234  27.17924  -58.73932 1.000 47.44128  -1 59  GLU B OE2 1 
ATOM   4239 N  N   . GLU B 1 60  ? 54.08411  22.83683  -56.53627 1.000 24.54921  ?  60  GLU B N   1 
ATOM   4240 C  CA  . GLU B 1 60  ? 53.44359  21.65269  -55.98234 1.000 24.41826  ?  60  GLU B CA  1 
ATOM   4241 C  C   . GLU B 1 60  ? 52.60327  22.00409  -54.76413 1.000 28.76544  ?  60  GLU B C   1 
ATOM   4242 O  O   . GLU B 1 60  ? 51.54863  21.40178  -54.54517 1.000 34.73277  ?  60  GLU B O   1 
ATOM   4243 C  CB  . GLU B 1 60  ? 54.49724  20.60182  -55.63186 1.000 26.48110  ?  60  GLU B CB  1 
ATOM   4244 C  CG  . GLU B 1 60  ? 55.21856  20.02846  -56.84126 1.000 26.79967  ?  60  GLU B CG  1 
ATOM   4245 C  CD  . GLU B 1 60  ? 56.21937  18.95060  -56.47251 1.000 34.62664  ?  60  GLU B CD  1 
ATOM   4246 O  OE1 . GLU B 1 60  ? 56.94328  19.12114  -55.46885 1.000 28.57801  ?  60  GLU B OE1 1 
ATOM   4247 O  OE2 . GLU B 1 60  ? 56.27807  17.92791  -57.18664 1.000 44.83887  -1 60  GLU B OE2 1 
ATOM   4248 N  N   . LYS B 1 61  ? 53.03989  22.98686  -53.97321 1.000 22.18216  ?  61  LYS B N   1 
ATOM   4249 C  CA  . LYS B 1 61  ? 52.22922  23.44587  -52.85164 1.000 26.31484  ?  61  LYS B CA  1 
ATOM   4250 C  C   . LYS B 1 61  ? 50.94796  24.12293  -53.32271 1.000 26.41308  ?  61  LYS B C   1 
ATOM   4251 O  O   . LYS B 1 61  ? 49.91221  23.99443  -52.66801 1.000 23.38048  ?  61  LYS B O   1 
ATOM   4252 C  CB  . LYS B 1 61  ? 53.03907  24.39095  -51.96465 1.000 24.19781  ?  61  LYS B CB  1 
ATOM   4253 C  CG  . LYS B 1 61  ? 54.10383  23.69933  -51.12864 1.000 19.64475  ?  61  LYS B CG  1 
ATOM   4254 C  CD  . LYS B 1 61  ? 54.97122  24.71196  -50.39963 1.000 27.86953  ?  61  LYS B CD  1 
ATOM   4255 C  CE  . LYS B 1 61  ? 56.09894  24.03224  -49.64181 1.000 28.74672  ?  61  LYS B CE  1 
ATOM   4256 N  NZ  . LYS B 1 61  ? 57.13589  25.00707  -49.20260 1.000 23.18145  ?  61  LYS B NZ  1 
ATOM   4257 N  N   . VAL B 1 62  ? 50.99249  24.84149  -54.44678 1.000 26.91586  ?  62  VAL B N   1 
ATOM   4258 C  CA  . VAL B 1 62  ? 49.77405  25.43255  -55.00240 1.000 27.97550  ?  62  VAL B CA  1 
ATOM   4259 C  C   . VAL B 1 62  ? 48.78952  24.33855  -55.40432 1.000 29.11677  ?  62  VAL B C   1 
ATOM   4260 O  O   . VAL B 1 62  ? 47.58985  24.39976  -55.09011 1.000 28.26792  ?  62  VAL B O   1 
ATOM   4261 C  CB  . VAL B 1 62  ? 50.11751  26.34450  -56.19475 1.000 24.24325  ?  62  VAL B CB  1 
ATOM   4262 C  CG1 . VAL B 1 62  ? 48.84847  26.82501  -56.88505 1.000 29.08511  ?  62  VAL B CG1 1 
ATOM   4263 C  CG2 . VAL B 1 62  ? 50.96116  27.52333  -55.73849 1.000 35.50630  ?  62  VAL B CG2 1 
ATOM   4264 N  N   . LEU B 1 63  ? 49.28698  23.31920  -56.11036 1.000 26.87808  ?  63  LEU B N   1 
ATOM   4265 C  CA  . LEU B 1 63  ? 48.42074  22.20702  -56.50257 1.000 20.76867  ?  63  LEU B CA  1 
ATOM   4266 C  C   . LEU B 1 63  ? 47.85252  21.49266  -55.27975 1.000 28.52431  ?  63  LEU B C   1 
ATOM   4267 O  O   . LEU B 1 63  ? 46.65684  21.15766  -55.23457 1.000 29.17011  ?  63  LEU B O   1 
ATOM   4268 C  CB  . LEU B 1 63  ? 49.19126  21.22886  -57.38808 1.000 16.62844  ?  63  LEU B CB  1 
ATOM   4269 C  CG  . LEU B 1 63  ? 49.30635  21.63124  -58.85756 1.000 22.34217  ?  63  LEU B CG  1 
ATOM   4270 C  CD1 . LEU B 1 63  ? 50.21789  20.67941  -59.61420 1.000 20.77025  ?  63  LEU B CD1 1 
ATOM   4271 C  CD2 . LEU B 1 63  ? 47.92416  21.66724  -59.48548 1.000 24.47029  ?  63  LEU B CD2 1 
ATOM   4272 N  N   . ASP B 1 64  ? 48.69874  21.26418  -54.27311 1.000 28.52502  ?  64  ASP B N   1 
ATOM   4273 C  CA  . ASP B 1 64  ? 48.25687  20.62016  -53.04399 1.000 23.11812  ?  64  ASP B CA  1 
ATOM   4274 C  C   . ASP B 1 64  ? 47.20540  21.45610  -52.32981 1.000 24.67275  ?  64  ASP B C   1 
ATOM   4275 O  O   . ASP B 1 64  ? 46.25227  20.91019  -51.77088 1.000 19.86870  ?  64  ASP B O   1 
ATOM   4276 C  CB  . ASP B 1 64  ? 49.45588  20.37159  -52.13038 1.000 18.95758  ?  64  ASP B CB  1 
ATOM   4277 C  CG  . ASP B 1 64  ? 49.04925  19.88006  -50.75876 1.000 27.28597  ?  64  ASP B CG  1 
ATOM   4278 O  OD1 . ASP B 1 64  ? 48.74997  18.67625  -50.62099 1.000 34.53896  ?  64  ASP B OD1 1 
ATOM   4279 O  OD2 . ASP B 1 64  ? 49.02503  20.69999  -49.81766 1.000 36.78264  -1 64  ASP B OD2 1 
ATOM   4280 N  N   . ASP B 1 65  ? 47.36915  22.78217  -52.32565 1.000 29.72917  ?  65  ASP B N   1 
ATOM   4281 C  CA  . ASP B 1 65  ? 46.38361  23.65429  -51.69576 1.000 23.59098  ?  65  ASP B CA  1 
ATOM   4282 C  C   . ASP B 1 65  ? 45.04409  23.57646  -52.41040 1.000 20.13285  ?  65  ASP B C   1 
ATOM   4283 O  O   . ASP B 1 65  ? 43.99136  23.55148  -51.76513 1.000 20.12702  ?  65  ASP B O   1 
ATOM   4284 C  CB  . ASP B 1 65  ? 46.88984  25.09661  -51.67020 1.000 23.26641  ?  65  ASP B CB  1 
ATOM   4285 C  CG  . ASP B 1 65  ? 47.99753  25.30849  -50.65807 1.000 46.03587  ?  65  ASP B CG  1 
ATOM   4286 O  OD1 . ASP B 1 65  ? 48.05267  24.54985  -49.66667 1.000 46.22444  ?  65  ASP B OD1 1 
ATOM   4287 O  OD2 . ASP B 1 65  ? 48.81085  26.23694  -50.85170 1.000 61.45964  -1 65  ASP B OD2 1 
ATOM   4288 N  N   . PHE B 1 66  ? 45.06167  23.54215  -53.74388 1.000 19.83781  ?  66  PHE B N   1 
ATOM   4289 C  CA  . PHE B 1 66  ? 43.81110  23.40099  -54.48801 1.000 23.84981  ?  66  PHE B CA  1 
ATOM   4290 C  C   . PHE B 1 66  ? 43.10443  22.09563  -54.12654 1.000 27.43838  ?  66  PHE B C   1 
ATOM   4291 O  O   . PHE B 1 66  ? 41.90398  22.08178  -53.79422 1.000 23.82652  ?  66  PHE B O   1 
ATOM   4292 C  CB  . PHE B 1 66  ? 44.09787  23.46705  -55.98877 1.000 25.35176  ?  66  PHE B CB  1 
ATOM   4293 C  CG  . PHE B 1 66  ? 42.86791  23.58026  -56.84071 1.000 32.81612  ?  66  PHE B CG  1 
ATOM   4294 C  CD1 . PHE B 1 66  ? 42.35120  24.82123  -57.16990 1.000 33.54747  ?  66  PHE B CD1 1 
ATOM   4295 C  CD2 . PHE B 1 66  ? 42.23344  22.44771  -57.32049 1.000 33.79238  ?  66  PHE B CD2 1 
ATOM   4296 C  CE1 . PHE B 1 66  ? 41.22326  24.92901  -57.95646 1.000 33.76281  ?  66  PHE B CE1 1 
ATOM   4297 C  CE2 . PHE B 1 66  ? 41.10624  22.54897  -58.10906 1.000 31.79428  ?  66  PHE B CE2 1 
ATOM   4298 C  CZ  . PHE B 1 66  ? 40.59872  23.79094  -58.42706 1.000 36.97646  ?  66  PHE B CZ  1 
ATOM   4299 N  N   . ILE B 1 67  ? 43.84921  20.98588  -54.16569 1.000 32.25551  ?  67  ILE B N   1 
ATOM   4300 C  CA  . ILE B 1 67  ? 43.25856  19.68327  -53.86335 1.000 23.93537  ?  67  ILE B CA  1 
ATOM   4301 C  C   . ILE B 1 67  ? 42.75248  19.64606  -52.42568 1.000 21.60891  ?  67  ILE B C   1 
ATOM   4302 O  O   . ILE B 1 67  ? 41.66420  19.12525  -52.14734 1.000 14.65348  ?  67  ILE B O   1 
ATOM   4303 C  CB  . ILE B 1 67  ? 44.27329  18.55774  -54.13906 1.000 24.95525  ?  67  ILE B CB  1 
ATOM   4304 C  CG1 . ILE B 1 67  ? 44.73791  18.60409  -55.59570 1.000 20.72477  ?  67  ILE B CG1 1 
ATOM   4305 C  CG2 . ILE B 1 67  ? 43.66443  17.19999  -53.82564 1.000 19.81846  ?  67  ILE B CG2 1 
ATOM   4306 C  CD1 . ILE B 1 67  ? 45.77946  17.56293  -55.93701 1.000 14.85328  ?  67  ILE B CD1 1 
ATOM   4307 N  N   . LEU B 1 68  ? 43.53677  20.19317  -51.49179 1.000 30.56854  ?  68  LEU B N   1 
ATOM   4308 C  CA  . LEU B 1 68  ? 43.14614  20.21864  -50.08727 1.000 28.54957  ?  68  LEU B CA  1 
ATOM   4309 C  C   . LEU B 1 68  ? 41.89063  21.04761  -49.87493 1.000 30.67354  ?  68  LEU B C   1 
ATOM   4310 O  O   . LEU B 1 68  ? 41.03040  20.67726  -49.07383 1.000 26.50657  ?  68  LEU B O   1 
ATOM   4311 C  CB  . LEU B 1 68  ? 44.28879  20.76630  -49.23128 1.000 23.67211  ?  68  LEU B CB  1 
ATOM   4312 C  CG  . LEU B 1 68  ? 45.35320  19.78411  -48.74451 1.000 23.90912  ?  68  LEU B CG  1 
ATOM   4313 C  CD1 . LEU B 1 68  ? 46.50275  20.52178  -48.07871 1.000 29.15268  ?  68  LEU B CD1 1 
ATOM   4314 C  CD2 . LEU B 1 68  ? 44.74386  18.76696  -47.79148 1.000 29.34630  ?  68  LEU B CD2 1 
ATOM   4315 N  N   . ALA B 1 69  ? 41.77562  22.18492  -50.56297 1.000 29.14753  ?  69  ALA B N   1 
ATOM   4316 C  CA  . ALA B 1 69  ? 40.57207  22.99750  -50.43754 1.000 29.12470  ?  69  ALA B CA  1 
ATOM   4317 C  C   . ALA B 1 69  ? 39.34504  22.21341  -50.87982 1.000 28.02623  ?  69  ALA B C   1 
ATOM   4318 O  O   . ALA B 1 69  ? 38.33267  22.16759  -50.16801 1.000 25.22490  ?  69  ALA B O   1 
ATOM   4319 C  CB  . ALA B 1 69  ? 40.71899  24.28301  -51.25188 1.000 40.10002  ?  69  ALA B CB  1 
ATOM   4320 N  N   . GLU B 1 70  ? 39.43246  21.55595  -52.04114 1.000 32.78042  ?  70  GLU B N   1 
ATOM   4321 C  CA  . GLU B 1 70  ? 38.29894  20.76146  -52.51817 1.000 26.23904  ?  70  GLU B CA  1 
ATOM   4322 C  C   . GLU B 1 70  ? 37.94730  19.64903  -51.53028 1.000 21.56297  ?  70  GLU B C   1 
ATOM   4323 O  O   . GLU B 1 70  ? 36.77808  19.47685  -51.14397 1.000 18.25706  ?  70  GLU B O   1 
ATOM   4324 C  CB  . GLU B 1 70  ? 38.62030  20.17977  -53.89609 1.000 22.35292  ?  70  GLU B CB  1 
ATOM   4325 C  CG  . GLU B 1 70  ? 37.56953  19.22996  -54.45159 1.000 22.90189  ?  70  GLU B CG  1 
ATOM   4326 C  CD  . GLU B 1 70  ? 36.52079  19.93442  -55.28964 1.000 33.23512  ?  70  GLU B CD  1 
ATOM   4327 O  OE1 . GLU B 1 70  ? 36.25796  21.12908  -55.04035 1.000 62.00640  ?  70  GLU B OE1 1 
ATOM   4328 O  OE2 . GLU B 1 70  ? 35.96421  19.29357  -56.20615 1.000 32.72930  -1 70  GLU B OE2 1 
ATOM   4329 N  N   . LYS B 1 71  ? 38.96102  18.89594  -51.09508 1.000 22.53478  ?  71  LYS B N   1 
ATOM   4330 C  CA  . LYS B 1 71  ? 38.73567  17.75223  -50.21810 1.000 24.09867  ?  71  LYS B CA  1 
ATOM   4331 C  C   . LYS B 1 71  ? 38.18111  18.17934  -48.86433 1.000 21.01418  ?  71  LYS B C   1 
ATOM   4332 O  O   . LYS B 1 71  ? 37.26925  17.53599  -48.33460 1.000 15.91577  ?  71  LYS B O   1 
ATOM   4333 C  CB  . LYS B 1 71  ? 40.03956  16.97529  -50.04704 1.000 24.68781  ?  71  LYS B CB  1 
ATOM   4334 C  CG  . LYS B 1 71  ? 39.96510  15.83069  -49.05912 1.000 28.98662  ?  71  LYS B CG  1 
ATOM   4335 C  CD  . LYS B 1 71  ? 41.29104  15.10170  -48.98883 1.000 35.09241  ?  71  LYS B CD  1 
ATOM   4336 C  CE  . LYS B 1 71  ? 41.26211  14.00241  -47.94777 1.000 35.02716  ?  71  LYS B CE  1 
ATOM   4337 N  NZ  . LYS B 1 71  ? 42.54764  13.26085  -47.93016 1.000 26.31392  ?  71  LYS B NZ  1 
ATOM   4338 N  N   . ARG B 1 72  ? 38.72321  19.25332  -48.28505 1.000 23.94137  ?  72  ARG B N   1 
ATOM   4339 C  CA  . ARG B 1 72  ? 38.24480  19.73348  -46.99506 1.000 19.50210  ?  72  ARG B CA  1 
ATOM   4340 C  C   . ARG B 1 72  ? 36.82930  20.27562  -47.10032 1.000 20.07682  ?  72  ARG B C   1 
ATOM   4341 O  O   . ARG B 1 72  ? 36.02302  20.08491  -46.18336 1.000 15.32595  ?  72  ARG B O   1 
ATOM   4342 C  CB  . ARG B 1 72  ? 39.19165  20.80077  -46.44795 1.000 19.97866  ?  72  ARG B CB  1 
ATOM   4343 C  CG  . ARG B 1 72  ? 40.49408  20.24730  -45.90035 1.000 19.84427  ?  72  ARG B CG  1 
ATOM   4344 C  CD  . ARG B 1 72  ? 41.57204  21.31208  -45.86460 1.000 19.60749  ?  72  ARG B CD  1 
ATOM   4345 N  NE  . ARG B 1 72  ? 42.80814  20.81385  -45.27464 1.000 25.09505  ?  72  ARG B NE  1 
ATOM   4346 C  CZ  . ARG B 1 72  ? 43.97853  21.43107  -45.35785 1.000 27.05118  ?  72  ARG B CZ  1 
ATOM   4347 N  NH1 . ARG B 1 72  ? 44.11483  22.56690  -46.02247 1.000 29.28043  ?  72  ARG B NH1 1 
ATOM   4348 N  NH2 . ARG B 1 72  ? 45.03973  20.89298  -44.76329 1.000 26.72461  ?  72  ARG B NH2 1 
ATOM   4349 N  N   . LYS B 1 73  ? 36.50504  20.95670  -48.20480 1.000 24.74556  ?  73  LYS B N   1 
ATOM   4350 C  CA  . LYS B 1 73  ? 35.12428  21.37209  -48.41969 1.000 19.77488  ?  73  LYS B CA  1 
ATOM   4351 C  C   . LYS B 1 73  ? 34.19194  20.17105  -48.38575 1.000 23.19303  ?  73  LYS B C   1 
ATOM   4352 O  O   . LYS B 1 73  ? 33.18664  20.17166  -47.66441 1.000 19.28450  ?  73  LYS B O   1 
ATOM   4353 C  CB  . LYS B 1 73  ? 34.99211  22.11161  -49.75046 1.000 24.34088  ?  73  LYS B CB  1 
ATOM   4354 C  CG  . LYS B 1 73  ? 33.54962  22.31662  -50.19176 1.000 22.93104  ?  73  LYS B CG  1 
ATOM   4355 C  CD  . LYS B 1 73  ? 33.47072  22.96387  -51.56556 1.000 48.84144  ?  73  LYS B CD  1 
ATOM   4356 C  CE  . LYS B 1 73  ? 34.09928  22.08250  -52.63370 1.000 34.85742  ?  73  LYS B CE  1 
ATOM   4357 N  NZ  . LYS B 1 73  ? 34.03072  22.71535  -53.98093 1.000 34.85631  ?  73  LYS B NZ  1 
ATOM   4358 N  N   . LEU B 1 74  ? 34.52886  19.12037  -49.14077 1.000 28.47887  ?  74  LEU B N   1 
ATOM   4359 C  CA  . LEU B 1 74  ? 33.66624  17.93972  -49.17193 1.000 20.71688  ?  74  LEU B CA  1 
ATOM   4360 C  C   . LEU B 1 74  ? 33.56038  17.28914  -47.79367 1.000 18.31673  ?  74  LEU B C   1 
ATOM   4361 O  O   . LEU B 1 74  ? 32.46091  16.94842  -47.33682 1.000 20.55292  ?  74  LEU B O   1 
ATOM   4362 C  CB  . LEU B 1 74  ? 34.17910  16.93944  -50.20807 1.000 17.06836  ?  74  LEU B CB  1 
ATOM   4363 C  CG  . LEU B 1 74  ? 34.00199  17.36797  -51.66629 1.000 16.46316  ?  74  LEU B CG  1 
ATOM   4364 C  CD1 . LEU B 1 74  ? 34.37528  16.23804  -52.61250 1.000 15.27876  ?  74  LEU B CD1 1 
ATOM   4365 C  CD2 . LEU B 1 74  ? 32.57679  17.83595  -51.91894 1.000 10.69418  ?  74  LEU B CD2 1 
ATOM   4366 N  N   . ILE B 1 75  ? 34.69479  17.13502  -47.10525 1.000 20.48410  ?  75  ILE B N   1 
ATOM   4367 C  CA  . ILE B 1 75  ? 34.70984  16.45318  -45.81143 1.000 17.48550  ?  75  ILE B CA  1 
ATOM   4368 C  C   . ILE B 1 75  ? 33.87771  17.21902  -44.78974 1.000 22.35349  ?  75  ILE B C   1 
ATOM   4369 O  O   . ILE B 1 75  ? 33.04308  16.64064  -44.08241 1.000 18.71399  ?  75  ILE B O   1 
ATOM   4370 C  CB  . ILE B 1 75  ? 36.15801  16.26319  -45.32375 1.000 13.26979  ?  75  ILE B CB  1 
ATOM   4371 C  CG1 . ILE B 1 75  ? 36.88618  15.22930  -46.18404 1.000 16.71286  ?  75  ILE B CG1 1 
ATOM   4372 C  CG2 . ILE B 1 75  ? 36.18265  15.85897  -43.85776 1.000 12.64520  ?  75  ILE B CG2 1 
ATOM   4373 C  CD1 . ILE B 1 75  ? 38.35797  15.09858  -45.86061 1.000 15.48804  ?  75  ILE B CD1 1 
ATOM   4374 N  N   . ASP B 1 76  ? 34.09076  18.53440  -44.69715 1.000 27.83368  ?  76  ASP B N   1 
ATOM   4375 C  CA  . ASP B 1 76  ? 33.39231  19.32539  -43.69110 1.000 22.44878  ?  76  ASP B CA  1 
ATOM   4376 C  C   . ASP B 1 76  ? 31.91201  19.46464  -44.01979 1.000 21.92553  ?  76  ASP B C   1 
ATOM   4377 O  O   . ASP B 1 76  ? 31.07118  19.45678  -43.11347 1.000 20.76966  ?  76  ASP B O   1 
ATOM   4378 C  CB  . ASP B 1 76  ? 34.05273  20.69568  -43.55265 1.000 19.40050  ?  76  ASP B CB  1 
ATOM   4379 C  CG  . ASP B 1 76  ? 35.43446  20.61319  -42.93231 1.000 30.16363  ?  76  ASP B CG  1 
ATOM   4380 O  OD1 . ASP B 1 76  ? 35.83561  19.50498  -42.51705 1.000 37.63768  ?  76  ASP B OD1 1 
ATOM   4381 O  OD2 . ASP B 1 76  ? 36.12000  21.65425  -42.85873 1.000 37.98130  -1 76  ASP B OD2 1 
ATOM   4382 N  N   . ASP B 1 77  ? 31.56695  19.59312  -45.30504 1.000 18.73070  ?  77  ASP B N   1 
ATOM   4383 C  CA  . ASP B 1 77  ? 30.15825  19.64291  -45.67665 1.000 19.91429  ?  77  ASP B CA  1 
ATOM   4384 C  C   . ASP B 1 77  ? 29.45614  18.33769  -45.32690 1.000 22.59893  ?  77  ASP B C   1 
ATOM   4385 O  O   . ASP B 1 77  ? 28.32381  18.34693  -44.82970 1.000 22.24578  ?  77  ASP B O   1 
ATOM   4386 C  CB  . ASP B 1 77  ? 30.02065  19.94893  -47.16791 1.000 20.84658  ?  77  ASP B CB  1 
ATOM   4387 C  CG  . ASP B 1 77  ? 28.60471  20.32407  -47.55897 1.000 24.38538  ?  77  ASP B CG  1 
ATOM   4388 O  OD1 . ASP B 1 77  ? 27.78160  20.57838  -46.65530 1.000 25.84604  ?  77  ASP B OD1 1 
ATOM   4389 O  OD2 . ASP B 1 77  ? 28.31424  20.36375  -48.77241 1.000 35.54926  -1 77  ASP B OD2 1 
ATOM   4390 N  N   . SER B 1 78  ? 30.11330  17.20157  -45.57677 1.000 29.43133  ?  78  SER B N   1 
ATOM   4391 C  CA  . SER B 1 78  ? 29.52380  15.91885  -45.20971 1.000 27.98685  ?  78  SER B CA  1 
ATOM   4392 C  C   . SER B 1 78  ? 29.38198  15.78036  -43.69733 1.000 25.22268  ?  78  SER B C   1 
ATOM   4393 O  O   . SER B 1 78  ? 28.34812  15.31125  -43.20668 1.000 22.65271  ?  78  SER B O   1 
ATOM   4394 C  CB  . SER B 1 78  ? 30.36650  14.77752  -45.77852 1.000 22.30935  ?  78  SER B CB  1 
ATOM   4395 O  OG  . SER B 1 78  ? 29.86091  13.51788  -45.37482 1.000 20.61841  ?  78  SER B OG  1 
ATOM   4396 N  N   . ARG B 1 79  ? 30.40504  16.18789  -42.94190 1.000 21.76590  ?  79  ARG B N   1 
ATOM   4397 C  CA  . ARG B 1 79  ? 30.40011  15.95252  -41.50084 1.000 19.37552  ?  79  ARG B CA  1 
ATOM   4398 C  C   . ARG B 1 79  ? 29.42362  16.87499  -40.77961 1.000 28.07452  ?  79  ARG B C   1 
ATOM   4399 O  O   . ARG B 1 79  ? 28.59507  16.41802  -39.98523 1.000 29.14366  ?  79  ARG B O   1 
ATOM   4400 C  CB  . ARG B 1 79  ? 31.81158  16.12563  -40.93754 1.000 13.56144  ?  79  ARG B CB  1 
ATOM   4401 C  CG  . ARG B 1 79  ? 31.89918  15.98587  -39.42075 1.000 16.36256  ?  79  ARG B CG  1 
ATOM   4402 C  CD  . ARG B 1 79  ? 33.34051  16.06107  -38.92728 1.000 22.37183  ?  79  ARG B CD  1 
ATOM   4403 N  NE  . ARG B 1 79  ? 33.88611  17.41315  -38.97788 1.000 25.25395  ?  79  ARG B NE  1 
ATOM   4404 C  CZ  . ARG B 1 79  ? 33.91191  18.24975  -37.94882 1.000 20.47235  ?  79  ARG B CZ  1 
ATOM   4405 N  NH1 . ARG B 1 79  ? 33.42574  17.90756  -36.76721 1.000 22.07407  ?  79  ARG B NH1 1 
ATOM   4406 N  NH2 . ARG B 1 79  ? 34.44032  19.45971  -38.10870 1.000 25.34828  ?  79  ARG B NH2 1 
ATOM   4407 N  N   . LEU B 1 80  ? 29.50790  18.17886  -41.03906 1.000 27.74762  ?  80  LEU B N   1 
ATOM   4408 C  CA  . LEU B 1 80  ? 28.79934  19.13911  -40.19991 1.000 20.99002  ?  80  LEU B CA  1 
ATOM   4409 C  C   . LEU B 1 80  ? 27.34947  19.31525  -40.63347 1.000 24.27096  ?  80  LEU B C   1 
ATOM   4410 O  O   . LEU B 1 80  ? 26.45125  19.38217  -39.78655 1.000 24.62777  ?  80  LEU B O   1 
ATOM   4411 C  CB  . LEU B 1 80  ? 29.53740  20.47523  -40.20264 1.000 17.18170  ?  80  LEU B CB  1 
ATOM   4412 C  CG  . LEU B 1 80  ? 30.87644  20.46502  -39.46343 1.000 19.94667  ?  80  LEU B CG  1 
ATOM   4413 C  CD1 . LEU B 1 80  ? 31.71539  21.67434  -39.84096 1.000 28.90869  ?  80  LEU B CD1 1 
ATOM   4414 C  CD2 . LEU B 1 80  ? 30.64411  20.42451  -37.96214 1.000 18.24668  ?  80  LEU B CD2 1 
ATOM   4415 N  N   . ASN B 1 81  ? 27.09718  19.39584  -41.93619 1.000 23.06898  ?  81  ASN B N   1 
ATOM   4416 C  CA  . ASN B 1 81  ? 25.72971  19.50937  -42.42473 1.000 22.52234  ?  81  ASN B CA  1 
ATOM   4417 C  C   . ASN B 1 81  ? 24.99462  18.17622  -42.43677 1.000 26.73077  ?  81  ASN B C   1 
ATOM   4418 O  O   . ASN B 1 81  ? 23.79768  18.15371  -42.74621 1.000 27.22760  ?  81  ASN B O   1 
ATOM   4419 C  CB  . ASN B 1 81  ? 25.71514  20.12401  -43.82625 1.000 26.73090  ?  81  ASN B CB  1 
ATOM   4420 C  CG  . ASN B 1 81  ? 25.66485  21.64096  -43.79669 1.000 28.02794  ?  81  ASN B CG  1 
ATOM   4421 O  OD1 . ASN B 1 81  ? 25.10874  22.23870  -42.87434 1.000 32.50631  ?  81  ASN B OD1 1 
ATOM   4422 N  ND2 . ASN B 1 81  ? 26.24233  22.27073  -44.81080 1.000 27.16329  ?  81  ASN B ND2 1 
ATOM   4423 N  N   . GLN B 1 82  ? 25.68072  17.07876  -42.11181 1.000 28.60920  ?  82  GLN B N   1 
ATOM   4424 C  CA  . GLN B 1 82  ? 25.08944  15.74269  -42.03827 1.000 29.15214  ?  82  GLN B CA  1 
ATOM   4425 C  C   . GLN B 1 82  ? 24.46177  15.33657  -43.37368 1.000 32.75859  ?  82  GLN B C   1 
ATOM   4426 O  O   . GLN B 1 82  ? 23.25842  15.09119  -43.48767 1.000 30.75426  ?  82  GLN B O   1 
ATOM   4427 C  CB  . GLN B 1 82  ? 24.07536  15.65072  -40.89239 1.000 43.04819  ?  82  GLN B CB  1 
ATOM   4428 C  CG  . GLN B 1 82  ? 24.70393  15.54395  -39.50601 1.000 48.32120  ?  82  GLN B CG  1 
ATOM   4429 C  CD  . GLN B 1 82  ? 25.22968  14.14958  -39.19169 1.000 55.25620  ?  82  GLN B CD  1 
ATOM   4430 O  OE1 . GLN B 1 82  ? 25.60350  13.38954  -40.08674 1.000 53.15829  ?  82  GLN B OE1 1 
ATOM   4431 N  NE2 . GLN B 1 82  ? 25.25297  13.80743  -37.90917 1.000 46.04488  ?  82  GLN B NE2 1 
ATOM   4432 N  N   . THR B 1 83  ? 25.31510  15.27618  -44.39148 1.000 27.30068  ?  83  THR B N   1 
ATOM   4433 C  CA  . THR B 1 83  ? 24.97585  14.70679  -45.68501 1.000 22.60239  ?  83  THR B CA  1 
ATOM   4434 C  C   . THR B 1 83  ? 26.02041  13.65435  -46.02587 1.000 26.63646  ?  83  THR B C   1 
ATOM   4435 O  O   . THR B 1 83  ? 27.10915  13.62812  -45.44786 1.000 30.20318  ?  83  THR B O   1 
ATOM   4436 C  CB  . THR B 1 83  ? 24.90640  15.77469  -46.78627 1.000 21.19797  ?  83  THR B CB  1 
ATOM   4437 O  OG1 . THR B 1 83  ? 26.12649  16.52621  -46.80722 1.000 20.99564  ?  83  THR B OG1 1 
ATOM   4438 C  CG2 . THR B 1 83  ? 23.73655  16.71762  -46.54063 1.000 23.26923  ?  83  THR B CG2 1 
ATOM   4439 N  N   . GLU B 1 84  ? 25.67608  12.77476  -46.96185 1.000 25.93079  ?  84  GLU B N   1 
ATOM   4440 C  CA  . GLU B 1 84  ? 26.53661  11.63832  -47.26242 1.000 26.64415  ?  84  GLU B CA  1 
ATOM   4441 C  C   . GLU B 1 84  ? 27.87289  12.09425  -47.83796 1.000 22.15841  ?  84  GLU B C   1 
ATOM   4442 O  O   . GLU B 1 84  ? 27.94422  13.06164  -48.60089 1.000 23.67153  ?  84  GLU B O   1 
ATOM   4443 C  CB  . GLU B 1 84  ? 25.84667  10.69046  -48.24264 1.000 29.00677  ?  84  GLU B CB  1 
ATOM   4444 C  CG  . GLU B 1 84  ? 26.58080  9.37269   -48.43100 1.000 36.06116  ?  84  GLU B CG  1 
ATOM   4445 C  CD  . GLU B 1 84  ? 26.00771  8.53641   -49.55321 1.000 35.58833  ?  84  GLU B CD  1 
ATOM   4446 O  OE1 . GLU B 1 84  ? 25.26406  9.09107   -50.38972 1.000 28.05408  ?  84  GLU B OE1 1 
ATOM   4447 O  OE2 . GLU B 1 84  ? 26.30221  7.32310   -49.59644 1.000 42.94672  -1 84  GLU B OE2 1 
ATOM   4448 N  N   . TYR B 1 85  ? 28.93817  11.38992  -47.45765 1.000 21.82461  ?  85  TYR B N   1 
ATOM   4449 C  CA  . TYR B 1 85  ? 30.26750  11.59643  -48.03010 1.000 19.38726  ?  85  TYR B CA  1 
ATOM   4450 C  C   . TYR B 1 85  ? 30.35356  10.74889  -49.29282 1.000 21.59998  ?  85  TYR B C   1 
ATOM   4451 O  O   . TYR B 1 85  ? 30.63810  9.55012   -49.23414 1.000 27.18697  ?  85  TYR B O   1 
ATOM   4452 C  CB  . TYR B 1 85  ? 31.35232  11.22855  -47.02460 1.000 18.33046  ?  85  TYR B CB  1 
ATOM   4453 C  CG  . TYR B 1 85  ? 32.75684  11.58517  -47.45813 1.000 17.04966  ?  85  TYR B CG  1 
ATOM   4454 C  CD1 . TYR B 1 85  ? 33.15791  12.91073  -47.55660 1.000 22.98400  ?  85  TYR B CD1 1 
ATOM   4455 C  CD2 . TYR B 1 85  ? 33.68758  10.59679  -47.74855 1.000 16.61010  ?  85  TYR B CD2 1 
ATOM   4456 C  CE1 . TYR B 1 85  ? 34.44229  13.24227  -47.94279 1.000 18.30620  ?  85  TYR B CE1 1 
ATOM   4457 C  CE2 . TYR B 1 85  ? 34.97560  10.91853  -48.13617 1.000 17.30822  ?  85  TYR B CE2 1 
ATOM   4458 C  CZ  . TYR B 1 85  ? 35.34653  12.24301  -48.23127 1.000 15.78087  ?  85  TYR B CZ  1 
ATOM   4459 O  OH  . TYR B 1 85  ? 36.62480  12.57332  -48.61523 1.000 10.12104  ?  85  TYR B OH  1 
ATOM   4460 N  N   . MET B 1 86  ? 30.09856  11.37838  -50.43825 1.000 19.67750  ?  86  MET B N   1 
ATOM   4461 C  CA  . MET B 1 86  ? 30.00216  10.63746  -51.69336 1.000 19.85696  ?  86  MET B CA  1 
ATOM   4462 C  C   . MET B 1 86  ? 31.24911  9.83081   -52.04842 1.000 21.36415  ?  86  MET B C   1 
ATOM   4463 O  O   . MET B 1 86  ? 31.08899  8.70110   -52.54317 1.000 17.36264  ?  86  MET B O   1 
ATOM   4464 C  CB  . MET B 1 86  ? 29.64093  11.60066  -52.82999 1.000 21.25279  ?  86  MET B CB  1 
ATOM   4465 C  CG  . MET B 1 86  ? 28.76925  10.96559  -53.89293 1.000 24.56646  ?  86  MET B CG  1 
ATOM   4466 S  SD  . MET B 1 86  ? 27.30363  10.22094  -53.15416 1.000 36.20359  ?  86  MET B SD  1 
ATOM   4467 C  CE  . MET B 1 86  ? 26.59068  9.39168   -54.57233 1.000 31.90962  ?  86  MET B CE  1 
ATOM   4468 N  N   . PRO B 1 87  ? 32.48177  10.32387  -51.86490 1.000 22.38323  ?  87  PRO B N   1 
ATOM   4469 C  CA  . PRO B 1 87  ? 33.64553  9.49327   -52.22220 1.000 18.74237  ?  87  PRO B CA  1 
ATOM   4470 C  C   . PRO B 1 87  ? 33.70564  8.16496   -51.48487 1.000 22.17759  ?  87  PRO B C   1 
ATOM   4471 O  O   . PRO B 1 87  ? 34.26344  7.19777   -52.01921 1.000 16.46424  ?  87  PRO B O   1 
ATOM   4472 C  CB  . PRO B 1 87  ? 34.83489  10.39181  -51.86156 1.000 12.86894  ?  87  PRO B CB  1 
ATOM   4473 C  CG  . PRO B 1 87  ? 34.30903  11.76569  -51.97978 1.000 12.28529  ?  87  PRO B CG  1 
ATOM   4474 C  CD  . PRO B 1 87  ? 32.89522  11.69063  -51.49325 1.000 17.55754  ?  87  PRO B CD  1 
ATOM   4475 N  N   . ALA B 1 88  ? 33.15315  8.08445   -50.27381 1.000 24.56510  ?  88  ALA B N   1 
ATOM   4476 C  CA  . ALA B 1 88  ? 33.15544  6.83680   -49.52088 1.000 18.06123  ?  88  ALA B CA  1 
ATOM   4477 C  C   . ALA B 1 88  ? 32.03714  5.88863   -49.93122 1.000 16.62227  ?  88  ALA B C   1 
ATOM   4478 O  O   . ALA B 1 88  ? 32.04605  4.72853   -49.50549 1.000 15.19360  ?  88  ALA B O   1 
ATOM   4479 C  CB  . ALA B 1 88  ? 33.05060  7.12563   -48.02171 1.000 16.91156  ?  88  ALA B CB  1 
ATOM   4480 N  N   . ALA B 1 89  ? 31.08630  6.34388   -50.74273 1.000 19.20876  ?  89  ALA B N   1 
ATOM   4481 C  CA  . ALA B 1 89  ? 29.96470  5.51346   -51.14942 1.000 21.14980  ?  89  ALA B CA  1 
ATOM   4482 C  C   . ALA B 1 89  ? 30.39502  4.53326   -52.23904 1.000 17.58171  ?  89  ALA B C   1 
ATOM   4483 O  O   . ALA B 1 89  ? 31.56618  4.45675   -52.62093 1.000 19.23619  ?  89  ALA B O   1 
ATOM   4484 C  CB  . ALA B 1 89  ? 28.80381  6.38544   -51.62143 1.000 24.41835  ?  89  ALA B CB  1 
ATOM   4485 N  N   . SER B 1 90  ? 29.42813  3.76916   -52.74419 1.000 16.25754  ?  90  SER B N   1 
ATOM   4486 C  CA  . SER B 1 90  ? 29.70311  2.82158   -53.81531 1.000 13.45315  ?  90  SER B CA  1 
ATOM   4487 C  C   . SER B 1 90  ? 30.16952  3.55175   -55.06712 1.000 15.94657  ?  90  SER B C   1 
ATOM   4488 O  O   . SER B 1 90  ? 29.71723  4.66053   -55.36455 1.000 22.35623  ?  90  SER B O   1 
ATOM   4489 C  CB  . SER B 1 90  ? 28.45590  1.99492   -54.12696 1.000 16.24071  ?  90  SER B CB  1 
ATOM   4490 O  OG  . SER B 1 90  ? 28.61609  1.27482   -55.33666 1.000 12.57511  ?  90  SER B OG  1 
ATOM   4491 N  N   . PHE B 1 91  ? 31.08997  2.92073   -55.80090 1.000 15.23925  ?  91  PHE B N   1 
ATOM   4492 C  CA  . PHE B 1 91  ? 31.61043  3.53391   -57.01814 1.000 17.89403  ?  91  PHE B CA  1 
ATOM   4493 C  C   . PHE B 1 91  ? 30.51217  3.75558   -58.04932 1.000 17.73539  ?  91  PHE B C   1 
ATOM   4494 O  O   . PHE B 1 91  ? 30.58733  4.70377   -58.83862 1.000 20.26821  ?  91  PHE B O   1 
ATOM   4495 C  CB  . PHE B 1 91  ? 32.72753  2.67142   -57.60528 1.000 15.95297  ?  91  PHE B CB  1 
ATOM   4496 C  CG  . PHE B 1 91  ? 33.35687  3.25299   -58.83862 1.000 18.05184  ?  91  PHE B CG  1 
ATOM   4497 C  CD1 . PHE B 1 91  ? 34.28919  4.27207   -58.74078 1.000 19.63745  ?  91  PHE B CD1 1 
ATOM   4498 C  CD2 . PHE B 1 91  ? 33.01938  2.77899   -60.09499 1.000 21.06163  ?  91  PHE B CD2 1 
ATOM   4499 C  CE1 . PHE B 1 91  ? 34.87106  4.80943   -59.87162 1.000 18.01340  ?  91  PHE B CE1 1 
ATOM   4500 C  CE2 . PHE B 1 91  ? 33.59848  3.31231   -61.23038 1.000 24.72006  ?  91  PHE B CE2 1 
ATOM   4501 C  CZ  . PHE B 1 91  ? 34.52549  4.32864   -61.11812 1.000 25.06085  ?  91  PHE B CZ  1 
ATOM   4502 N  N   . TYR B 1 92  ? 29.48405  2.90396   -58.05012 1.000 15.35502  ?  92  TYR B N   1 
ATOM   4503 C  CA  . TYR B 1 92  ? 28.36205  3.08651   -58.96601 1.000 19.83387  ?  92  TYR B CA  1 
ATOM   4504 C  C   . TYR B 1 92  ? 27.69487  4.43931   -58.75334 1.000 22.63589  ?  92  TYR B C   1 
ATOM   4505 O  O   . TYR B 1 92  ? 27.49625  5.20644   -59.70271 1.000 23.88047  ?  92  TYR B O   1 
ATOM   4506 C  CB  . TYR B 1 92  ? 27.35176  1.95287   -58.77695 1.000 19.91826  ?  92  TYR B CB  1 
ATOM   4507 C  CG  . TYR B 1 92  ? 26.03795  2.15383   -59.50215 1.000 20.41577  ?  92  TYR B CG  1 
ATOM   4508 C  CD1 . TYR B 1 92  ? 25.87874  1.73605   -60.81555 1.000 24.55128  ?  92  TYR B CD1 1 
ATOM   4509 C  CD2 . TYR B 1 92  ? 24.95344  2.75046   -58.86933 1.000 17.24026  ?  92  TYR B CD2 1 
ATOM   4510 C  CE1 . TYR B 1 92  ? 24.68033  1.91246   -61.48315 1.000 19.93118  ?  92  TYR B CE1 1 
ATOM   4511 C  CE2 . TYR B 1 92  ? 23.75246  2.93214   -59.52849 1.000 22.01184  ?  92  TYR B CE2 1 
ATOM   4512 C  CZ  . TYR B 1 92  ? 23.62085  2.51043   -60.83523 1.000 20.77777  ?  92  TYR B CZ  1 
ATOM   4513 O  OH  . TYR B 1 92  ? 22.42646  2.68744   -61.49705 1.000 19.85713  ?  92  TYR B OH  1 
ATOM   4514 N  N   . ARG B 1 93  ? 27.34588  4.74946   -57.50542 1.000 21.20370  ?  93  ARG B N   1 
ATOM   4515 C  CA  . ARG B 1 93  ? 26.65767  5.99723   -57.20428 1.000 20.25606  ?  93  ARG B CA  1 
ATOM   4516 C  C   . ARG B 1 93  ? 27.59505  7.19664   -57.24514 1.000 25.29159  ?  93  ARG B C   1 
ATOM   4517 O  O   . ARG B 1 93  ? 27.16535  8.30138   -57.59640 1.000 31.52685  ?  93  ARG B O   1 
ATOM   4518 C  CB  . ARG B 1 93  ? 25.99103  5.89707   -55.83297 1.000 19.59405  ?  93  ARG B CB  1 
ATOM   4519 C  CG  . ARG B 1 93  ? 25.20126  4.61436   -55.63516 1.000 18.60842  ?  93  ARG B CG  1 
ATOM   4520 C  CD  . ARG B 1 93  ? 24.72931  4.45309   -54.19937 1.000 19.09165  ?  93  ARG B CD  1 
ATOM   4521 N  NE  . ARG B 1 93  ? 23.85591  5.54298   -53.78147 1.000 31.29255  ?  93  ARG B NE  1 
ATOM   4522 C  CZ  . ARG B 1 93  ? 24.22726  6.53885   -52.98870 1.000 31.94890  ?  93  ARG B CZ  1 
ATOM   4523 N  NH1 . ARG B 1 93  ? 25.45220  6.60796   -52.49388 1.000 30.69296  ?  93  ARG B NH1 1 
ATOM   4524 N  NH2 . ARG B 1 93  ? 23.34679  7.48758   -52.68288 1.000 35.60082  ?  93  ARG B NH2 1 
ATOM   4525 N  N   . SER B 1 94  ? 28.86520  7.00317   -56.89931 1.000 20.74986  ?  94  SER B N   1 
ATOM   4526 C  CA  . SER B 1 94  ? 29.81608  8.09927   -56.78171 1.000 19.97258  ?  94  SER B CA  1 
ATOM   4527 C  C   . SER B 1 94  ? 30.58412  8.37988   -58.06615 1.000 15.73403  ?  94  SER B C   1 
ATOM   4528 O  O   . SER B 1 94  ? 31.36257  9.33585   -58.09793 1.000 16.26033  ?  94  SER B O   1 
ATOM   4529 C  CB  . SER B 1 94  ? 30.81354  7.81096   -55.65538 1.000 21.08718  ?  94  SER B CB  1 
ATOM   4530 O  OG  . SER B 1 94  ? 31.70266  6.76992   -56.02068 1.000 18.76243  ?  94  SER B OG  1 
ATOM   4531 N  N   . LYS B 1 95  ? 30.39288  7.57985   -59.11767 1.000 20.81497  ?  95  LYS B N   1 
ATOM   4532 C  CA  . LYS B 1 95  ? 31.20135  7.73693   -60.32401 1.000 23.58814  ?  95  LYS B CA  1 
ATOM   4533 C  C   . LYS B 1 95  ? 30.98952  9.10379   -60.96553 1.000 22.64955  ?  95  LYS B C   1 
ATOM   4534 O  O   . LYS B 1 95  ? 31.95300  9.82327   -61.25248 1.000 21.94085  ?  95  LYS B O   1 
ATOM   4535 C  CB  . LYS B 1 95  ? 30.87656  6.61999   -61.31582 1.000 22.49238  ?  95  LYS B CB  1 
ATOM   4536 C  CG  . LYS B 1 95  ? 31.67662  6.68266   -62.60401 1.000 22.71844  ?  95  LYS B CG  1 
ATOM   4537 C  CD  . LYS B 1 95  ? 31.18638  5.64716   -63.60087 1.000 27.66012  ?  95  LYS B CD  1 
ATOM   4538 C  CE  . LYS B 1 95  ? 31.94809  5.73488   -64.91181 1.000 28.08170  ?  95  LYS B CE  1 
ATOM   4539 N  NZ  . LYS B 1 95  ? 31.39295  4.80334   -65.93174 1.000 23.13632  ?  95  LYS B NZ  1 
ATOM   4540 N  N   . ASP B 1 96  ? 29.73001  9.48231   -61.19380 1.000 23.94951  ?  96  ASP B N   1 
ATOM   4541 C  CA  . ASP B 1 96  ? 29.44777  10.75817  -61.84624 1.000 22.39642  ?  96  ASP B CA  1 
ATOM   4542 C  C   . ASP B 1 96  ? 29.83977  11.93472  -60.95777 1.000 19.28848  ?  96  ASP B C   1 
ATOM   4543 O  O   . ASP B 1 96  ? 30.36687  12.94617  -61.44525 1.000 19.19645  ?  96  ASP B O   1 
ATOM   4544 C  CB  . ASP B 1 96  ? 27.96993  10.82537  -62.22952 1.000 32.61384  ?  96  ASP B CB  1 
ATOM   4545 C  CG  . ASP B 1 96  ? 27.52631  9.62353   -63.05070 1.000 30.09417  ?  96  ASP B CG  1 
ATOM   4546 O  OD1 . ASP B 1 96  ? 28.37239  9.03956   -63.76150 1.000 28.13077  ?  96  ASP B OD1 1 
ATOM   4547 O  OD2 . ASP B 1 96  ? 26.33283  9.26000   -62.98393 1.000 28.50278  -1 96  ASP B OD2 1 
ATOM   4548 N  N   . PHE B 1 97  ? 29.60053  11.81591  -59.64939 1.000 21.81606  ?  97  PHE B N   1 
ATOM   4549 C  CA  . PHE B 1 97  ? 30.03251  12.85731  -58.72434 1.000 20.93572  ?  97  PHE B CA  1 
ATOM   4550 C  C   . PHE B 1 97  ? 31.54032  13.06012  -58.79567 1.000 20.84913  ?  97  PHE B C   1 
ATOM   4551 O  O   . PHE B 1 97  ? 32.01891  14.19890  -58.80840 1.000 22.68152  ?  97  PHE B O   1 
ATOM   4552 C  CB  . PHE B 1 97  ? 29.60229  12.50741  -57.29960 1.000 15.59002  ?  97  PHE B CB  1 
ATOM   4553 C  CG  . PHE B 1 97  ? 30.28709  13.32613  -56.24164 1.000 19.48760  ?  97  PHE B CG  1 
ATOM   4554 C  CD1 . PHE B 1 97  ? 29.79681  14.57004  -55.88385 1.000 24.05945  ?  97  PHE B CD1 1 
ATOM   4555 C  CD2 . PHE B 1 97  ? 31.42163  12.84951  -55.60197 1.000 22.82083  ?  97  PHE B CD2 1 
ATOM   4556 C  CE1 . PHE B 1 97  ? 30.42610  15.32468  -54.91052 1.000 23.77075  ?  97  PHE B CE1 1 
ATOM   4557 C  CE2 . PHE B 1 97  ? 32.05556  13.59957  -54.63045 1.000 20.88608  ?  97  PHE B CE2 1 
ATOM   4558 C  CZ  . PHE B 1 97  ? 31.55641  14.83769  -54.28344 1.000 21.39163  ?  97  PHE B CZ  1 
ATOM   4559 N  N   . ILE B 1 98  ? 32.30452  11.96594  -58.84459 1.000 22.72136  ?  98  ILE B N   1 
ATOM   4560 C  CA  . ILE B 1 98  ? 33.75072  12.06844  -59.02016 1.000 21.46618  ?  98  ILE B CA  1 
ATOM   4561 C  C   . ILE B 1 98  ? 34.07416  12.73278  -60.35045 1.000 23.18487  ?  98  ILE B C   1 
ATOM   4562 O  O   . ILE B 1 98  ? 34.96422  13.58768  -60.43855 1.000 23.79489  ?  98  ILE B O   1 
ATOM   4563 C  CB  . ILE B 1 98  ? 34.40002  10.67594  -58.90984 1.000 19.21985  ?  98  ILE B CB  1 
ATOM   4564 C  CG1 . ILE B 1 98  ? 34.27222  10.13803  -57.48379 1.000 19.09871  ?  98  ILE B CG1 1 
ATOM   4565 C  CG2 . ILE B 1 98  ? 35.85820  10.72585  -59.33924 1.000 19.39161  ?  98  ILE B CG2 1 
ATOM   4566 C  CD1 . ILE B 1 98  ? 34.71764  8.70135   -57.32904 1.000 17.20015  ?  98  ILE B CD1 1 
ATOM   4567 N  N   . ASP B 1 99  ? 33.34308  12.36397  -61.40229 1.000 24.12158  ?  99  ASP B N   1 
ATOM   4568 C  CA  . ASP B 1 99  ? 33.56325  12.94463  -62.71978 1.000 20.87801  ?  99  ASP B CA  1 
ATOM   4569 C  C   . ASP B 1 99  ? 33.20673  14.42374  -62.78076 1.000 23.83844  ?  99  ASP B C   1 
ATOM   4570 O  O   . ASP B 1 99  ? 33.52531  15.07391  -63.78074 1.000 27.77413  ?  99  ASP B O   1 
ATOM   4571 C  CB  . ASP B 1 99  ? 32.76098  12.18082  -63.77712 1.000 23.68463  ?  99  ASP B CB  1 
ATOM   4572 C  CG  . ASP B 1 99  ? 33.19565  10.73363  -63.90906 1.000 27.53708  ?  99  ASP B CG  1 
ATOM   4573 O  OD1 . ASP B 1 99  ? 34.36873  10.43312  -63.60318 1.000 26.39882  ?  99  ASP B OD1 1 
ATOM   4574 O  OD2 . ASP B 1 99  ? 32.36344  9.89669   -64.32056 1.000 33.49215  -1 99  ASP B OD2 1 
ATOM   4575 N  N   . THR B 1 100 ? 32.53621  14.96621  -61.76413 1.000 24.39760  ?  100 THR B N   1 
ATOM   4576 C  CA  . THR B 1 100 ? 32.23825  16.39443  -61.72821 1.000 20.72371  ?  100 THR B CA  1 
ATOM   4577 C  C   . THR B 1 100 ? 33.09063  17.17266  -60.72597 1.000 25.20235  ?  100 THR B C   1 
ATOM   4578 O  O   . THR B 1 100 ? 32.75223  18.31729  -60.40809 1.000 29.72214  ?  100 THR B O   1 
ATOM   4579 C  CB  . THR B 1 100 ? 30.75421  16.62577  -61.42915 1.000 15.78157  ?  100 THR B CB  1 
ATOM   4580 O  OG1 . THR B 1 100 ? 30.42826  16.08488  -60.14387 1.000 26.37951  ?  100 THR B OG1 1 
ATOM   4581 C  CG2 . THR B 1 100 ? 29.88570  15.96842  -62.49122 1.000 20.57807  ?  100 THR B CG2 1 
ATOM   4582 N  N   . THR B 1 101 ? 34.18129  16.59865  -60.22265 1.000 33.14471  ?  101 THR B N   1 
ATOM   4583 C  CA  . THR B 1 101 ? 35.04930  17.30240  -59.28567 1.000 35.40994  ?  101 THR B CA  1 
ATOM   4584 C  C   . THR B 1 101 ? 36.26899  17.88316  -59.99556 1.000 33.94214  ?  101 THR B C   1 
ATOM   4585 O  O   . THR B 1 101 ? 36.64755  17.45747  -61.08950 1.000 36.77595  ?  101 THR B O   1 
ATOM   4586 C  CB  . THR B 1 101 ? 35.52092  16.38380  -58.15116 1.000 28.57398  ?  101 THR B CB  1 
ATOM   4587 O  OG1 . THR B 1 101 ? 36.41583  15.39317  -58.67031 1.000 22.71312  ?  101 THR B OG1 1 
ATOM   4588 C  CG2 . THR B 1 101 ? 34.34673  15.70149  -57.47712 1.000 23.44463  ?  101 THR B CG2 1 
ATOM   4589 N  N   . PHE B 1 102 ? 36.88036  18.88012  -59.35012 1.000 28.29203  ?  102 PHE B N   1 
ATOM   4590 C  CA  . PHE B 1 102 ? 38.14399  19.42785  -59.83400 1.000 34.53424  ?  102 PHE B CA  1 
ATOM   4591 C  C   . PHE B 1 102 ? 39.32010  18.52371  -59.47606 1.000 30.21649  ?  102 PHE B C   1 
ATOM   4592 O  O   . PHE B 1 102 ? 40.27196  18.39045  -60.25887 1.000 30.67383  ?  102 PHE B O   1 
ATOM   4593 C  CB  . PHE B 1 102 ? 38.36462  20.82752  -59.25914 1.000 40.29907  ?  102 PHE B CB  1 
ATOM   4594 C  CG  . PHE B 1 102 ? 37.20164  21.76075  -59.45304 1.000 40.66682  ?  102 PHE B CG  1 
ATOM   4595 C  CD1 . PHE B 1 102 ? 37.02098  22.42514  -60.65581 1.000 31.97961  ?  102 PHE B CD1 1 
ATOM   4596 C  CD2 . PHE B 1 102 ? 36.29930  21.98753  -58.42536 1.000 32.38783  ?  102 PHE B CD2 1 
ATOM   4597 C  CE1 . PHE B 1 102 ? 35.95628  23.28954  -60.83434 1.000 23.42092  ?  102 PHE B CE1 1 
ATOM   4598 C  CE2 . PHE B 1 102 ? 35.23326  22.85121  -58.59707 1.000 29.52340  ?  102 PHE B CE2 1 
ATOM   4599 C  CZ  . PHE B 1 102 ? 35.06170  23.50287  -59.80357 1.000 28.23123  ?  102 PHE B CZ  1 
ATOM   4600 N  N   . ALA B 1 103 ? 39.27039  17.90286  -58.29385 1.000 26.78220  ?  103 ALA B N   1 
ATOM   4601 C  CA  . ALA B 1 103 ? 40.36754  17.04811  -57.85371 1.000 22.72918  ?  103 ALA B CA  1 
ATOM   4602 C  C   . ALA B 1 103 ? 40.54887  15.86213  -58.78968 1.000 28.38589  ?  103 ALA B C   1 
ATOM   4603 O  O   . ALA B 1 103 ? 41.68115  15.45380  -59.07691 1.000 26.51775  ?  103 ALA B O   1 
ATOM   4604 C  CB  . ALA B 1 103 ? 40.12059  16.57211  -56.42242 1.000 18.17417  ?  103 ALA B CB  1 
ATOM   4605 N  N   . TYR B 1 104 ? 39.44366  15.29200  -59.27436 1.000 29.68384  ?  104 TYR B N   1 
ATOM   4606 C  CA  . TYR B 1 104 ? 39.55300  14.20690  -60.24071 1.000 28.52467  ?  104 TYR B CA  1 
ATOM   4607 C  C   . TYR B 1 104 ? 40.15937  14.68590  -61.55305 1.000 26.91131  ?  104 TYR B C   1 
ATOM   4608 O  O   . TYR B 1 104 ? 40.88583  13.93103  -62.20175 1.000 24.44856  ?  104 TYR B O   1 
ATOM   4609 C  CB  . TYR B 1 104 ? 38.18795  13.56589  -60.48196 1.000 26.75520  ?  104 TYR B CB  1 
ATOM   4610 C  CG  . TYR B 1 104 ? 38.22767  12.43227  -61.47603 1.000 20.90288  ?  104 TYR B CG  1 
ATOM   4611 C  CD1 . TYR B 1 104 ? 39.03308  11.32324  -61.25866 1.000 21.45139  ?  104 TYR B CD1 1 
ATOM   4612 C  CD2 . TYR B 1 104 ? 37.46061  12.46928  -62.63052 1.000 22.11554  ?  104 TYR B CD2 1 
ATOM   4613 C  CE1 . TYR B 1 104 ? 39.07573  10.28437  -62.16550 1.000 25.90858  ?  104 TYR B CE1 1 
ATOM   4614 C  CE2 . TYR B 1 104 ? 37.49440  11.43376  -63.54190 1.000 22.94456  ?  104 TYR B CE2 1 
ATOM   4615 C  CZ  . TYR B 1 104 ? 38.30494  10.34440  -63.30654 1.000 24.77995  ?  104 TYR B CZ  1 
ATOM   4616 O  OH  . TYR B 1 104 ? 38.34196  9.31068   -64.21440 1.000 23.28878  ?  104 TYR B OH  1 
ATOM   4617 N  N   . LYS B 1 105 ? 39.88496  15.93005  -61.95596 1.000 28.54478  ?  105 LYS B N   1 
ATOM   4618 C  CA  . LYS B 1 105 ? 40.54642  16.48962  -63.13305 1.000 23.37276  ?  105 LYS B CA  1 
ATOM   4619 C  C   . LYS B 1 105 ? 42.05281  16.59023  -62.92285 1.000 21.32005  ?  105 LYS B C   1 
ATOM   4620 O  O   . LYS B 1 105 ? 42.84189  16.22711  -63.80878 1.000 22.66161  ?  105 LYS B O   1 
ATOM   4621 C  CB  . LYS B 1 105 ? 39.95353  17.86205  -63.45799 1.000 29.98099  ?  105 LYS B CB  1 
ATOM   4622 C  CG  . LYS B 1 105 ? 40.76977  18.71197  -64.42819 1.000 32.96648  ?  105 LYS B CG  1 
ATOM   4623 C  CD  . LYS B 1 105 ? 40.89498  18.06496  -65.79742 1.000 29.75352  ?  105 LYS B CD  1 
ATOM   4624 C  CE  . LYS B 1 105 ? 41.19013  19.10301  -66.86801 1.000 26.52045  ?  105 LYS B CE  1 
ATOM   4625 N  NZ  . LYS B 1 105 ? 42.38323  19.92803  -66.53627 1.000 26.96932  ?  105 LYS B NZ  1 
ATOM   4626 N  N   . ILE B 1 106 ? 42.47053  17.07348  -61.74991 1.000 24.53019  ?  106 ILE B N   1 
ATOM   4627 C  CA  . ILE B 1 106 ? 43.89949  17.16675  -61.46035 1.000 23.56134  ?  106 ILE B CA  1 
ATOM   4628 C  C   . ILE B 1 106 ? 44.53859  15.78424  -61.48694 1.000 22.71893  ?  106 ILE B C   1 
ATOM   4629 O  O   . ILE B 1 106 ? 45.62537  15.59606  -62.04795 1.000 20.96465  ?  106 ILE B O   1 
ATOM   4630 C  CB  . ILE B 1 106 ? 44.13380  17.87203  -60.11187 1.000 20.00708  ?  106 ILE B CB  1 
ATOM   4631 C  CG1 . ILE B 1 106 ? 43.69487  19.33315  -60.18985 1.000 21.41431  ?  106 ILE B CG1 1 
ATOM   4632 C  CG2 . ILE B 1 106 ? 45.59887  17.78023  -59.70896 1.000 25.09627  ?  106 ILE B CG2 1 
ATOM   4633 C  CD1 . ILE B 1 106 ? 44.15897  20.16376  -59.01812 1.000 31.16457  ?  106 ILE B CD1 1 
ATOM   4634 N  N   . ILE B 1 107 ? 43.87303  14.79525  -60.88641 1.000 21.99015  ?  107 ILE B N   1 
ATOM   4635 C  CA  . ILE B 1 107 ? 44.41027  13.43623  -60.87550 1.000 21.39343  ?  107 ILE B CA  1 
ATOM   4636 C  C   . ILE B 1 107 ? 44.46353  12.87075  -62.29118 1.000 24.69731  ?  107 ILE B C   1 
ATOM   4637 O  O   . ILE B 1 107 ? 45.39551  12.13956  -62.64964 1.000 22.78614  ?  107 ILE B O   1 
ATOM   4638 C  CB  . ILE B 1 107 ? 43.58497  12.54652  -59.92728 1.000 22.27418  ?  107 ILE B CB  1 
ATOM   4639 C  CG1 . ILE B 1 107 ? 43.71401  13.05892  -58.49193 1.000 20.27682  ?  107 ILE B CG1 1 
ATOM   4640 C  CG2 . ILE B 1 107 ? 44.03442  11.09566  -60.01465 1.000 28.27149  ?  107 ILE B CG2 1 
ATOM   4641 C  CD1 . ILE B 1 107 ? 42.89761  12.28667  -57.48620 1.000 18.80503  ?  107 ILE B CD1 1 
ATOM   4642 N  N   . GLN B 1 108 ? 43.46816  13.20358  -63.11807 1.000 27.18347  ?  108 GLN B N   1 
ATOM   4643 C  CA  . GLN B 1 108 ? 43.48695  12.80358  -64.52144 1.000 22.99477  ?  108 GLN B CA  1 
ATOM   4644 C  C   . GLN B 1 108 ? 44.73132  13.32792  -65.22172 1.000 23.86845  ?  108 GLN B C   1 
ATOM   4645 O  O   . GLN B 1 108 ? 45.44216  12.57548  -65.89726 1.000 27.93527  ?  108 GLN B O   1 
ATOM   4646 C  CB  . GLN B 1 108 ? 42.23272  13.31450  -65.23301 1.000 21.37956  ?  108 GLN B CB  1 
ATOM   4647 C  CG  . GLN B 1 108 ? 41.00054  12.43826  -65.10302 1.000 23.99606  ?  108 GLN B CG  1 
ATOM   4648 C  CD  . GLN B 1 108 ? 39.85974  12.93141  -65.97705 1.000 30.96755  ?  108 GLN B CD  1 
ATOM   4649 O  OE1 . GLN B 1 108 ? 39.84644  14.08630  -66.40418 1.000 29.55948  ?  108 GLN B OE1 1 
ATOM   4650 N  NE2 . GLN B 1 108 ? 38.90378  12.05406  -66.25792 1.000 34.66135  ?  108 GLN B NE2 1 
ATOM   4651 N  N   . ASP B 1 109 ? 45.01515  14.62296  -65.06659 1.000 27.02843  ?  109 ASP B N   1 
ATOM   4652 C  CA  . ASP B 1 109 ? 46.19295  15.18907  -65.71599 1.000 26.76094  ?  109 ASP B CA  1 
ATOM   4653 C  C   . ASP B 1 109 ? 47.49528  14.72124  -65.07453 1.000 22.74402  ?  109 ASP B C   1 
ATOM   4654 O  O   . ASP B 1 109 ? 48.55993  14.87189  -65.68355 1.000 15.91056  ?  109 ASP B O   1 
ATOM   4655 C  CB  . ASP B 1 109 ? 46.12105  16.71731  -65.69978 1.000 26.51283  ?  109 ASP B CB  1 
ATOM   4656 C  CG  . ASP B 1 109 ? 45.00370  17.25888  -66.57270 1.000 25.78264  ?  109 ASP B CG  1 
ATOM   4657 O  OD1 . ASP B 1 109 ? 44.28435  16.45011  -67.19627 1.000 25.43509  ?  109 ASP B OD1 1 
ATOM   4658 O  OD2 . ASP B 1 109 ? 44.84591  18.49570  -66.63764 1.000 36.07679  -1 109 ASP B OD2 1 
ATOM   4659 N  N   . MET B 1 110 ? 47.43230  14.15009  -63.87603 1.000 22.95269  ?  110 MET B N   1 
ATOM   4660 C  CA  . MET B 1 110 ? 48.62959  13.78588  -63.12399 1.000 19.59865  ?  110 MET B CA  1 
ATOM   4661 C  C   . MET B 1 110 ? 49.21152  12.47080  -63.63339 1.000 29.25749  ?  110 MET B C   1 
ATOM   4662 O  O   . MET B 1 110 ? 48.48886  11.47319  -63.72092 1.000 37.18734  ?  110 MET B O   1 
ATOM   4663 C  CB  . MET B 1 110 ? 48.30463  13.66115  -61.64056 1.000 18.35065  ?  110 MET B CB  1 
ATOM   4664 C  CG  . MET B 1 110 ? 49.44929  13.13126  -60.79932 1.000 18.89012  ?  110 MET B CG  1 
ATOM   4665 S  SD  . MET B 1 110 ? 48.95997  12.82918  -59.09188 1.000 29.29935  ?  110 MET B SD  1 
ATOM   4666 C  CE  . MET B 1 110 ? 48.21101  14.40220  -58.67338 1.000 27.17516  ?  110 MET B CE  1 
ATOM   4667 N  N   . PRO B 1 111 ? 50.50013  12.42846  -63.97631 1.000 28.98211  ?  111 PRO B N   1 
ATOM   4668 C  CA  . PRO B 1 111 ? 51.15496  11.14062  -64.25922 1.000 29.85429  ?  111 PRO B CA  1 
ATOM   4669 C  C   . PRO B 1 111 ? 51.41756  10.38277  -62.96529 1.000 26.85478  ?  111 PRO B C   1 
ATOM   4670 O  O   . PRO B 1 111 ? 52.19914  10.82359  -62.11989 1.000 24.79385  ?  111 PRO B O   1 
ATOM   4671 C  CB  . PRO B 1 111 ? 52.45725  11.54951  -64.95644 1.000 33.26965  ?  111 PRO B CB  1 
ATOM   4672 C  CG  . PRO B 1 111 ? 52.72705  12.92720  -64.45989 1.000 24.18059  ?  111 PRO B CG  1 
ATOM   4673 C  CD  . PRO B 1 111 ? 51.38862  13.57308  -64.23804 1.000 20.07312  ?  111 PRO B CD  1 
ATOM   4674 N  N   . LYS B 1 112 ? 50.76191  9.23435   -62.81668 1.000 27.18841  ?  112 LYS B N   1 
ATOM   4675 C  CA  . LYS B 1 112 ? 50.77269  8.48635   -61.56577 1.000 27.16452  ?  112 LYS B CA  1 
ATOM   4676 C  C   . LYS B 1 112 ? 51.84142  7.40316   -61.51521 1.000 28.05420  ?  112 LYS B C   1 
ATOM   4677 O  O   . LYS B 1 112 ? 51.90752  6.66636   -60.52550 1.000 24.59027  ?  112 LYS B O   1 
ATOM   4678 C  CB  . LYS B 1 112 ? 49.39856  7.86020   -61.32531 1.000 21.29472  ?  112 LYS B CB  1 
ATOM   4679 C  CG  . LYS B 1 112 ? 48.26728  8.85608   -61.42324 1.000 20.89088  ?  112 LYS B CG  1 
ATOM   4680 C  CD  . LYS B 1 112 ? 46.93850  8.15846   -61.58529 1.000 25.18883  ?  112 LYS B CD  1 
ATOM   4681 C  CE  . LYS B 1 112 ? 46.00821  9.00171   -62.42361 1.000 22.56509  ?  112 LYS B CE  1 
ATOM   4682 N  NZ  . LYS B 1 112 ? 46.60665  9.29262   -63.75096 1.000 15.76566  ?  112 LYS B NZ  1 
ATOM   4683 N  N   . GLY B 1 113 ? 52.66723  7.28518   -62.53700 1.000 26.90502  ?  113 GLY B N   1 
ATOM   4684 C  CA  . GLY B 1 113 ? 53.73046  6.27943   -62.53521 1.000 20.05535  ?  113 GLY B CA  1 
ATOM   4685 C  C   . GLY B 1 113 ? 53.28226  4.98028   -63.20782 1.000 32.89722  ?  113 GLY B C   1 
ATOM   4686 O  O   . GLY B 1 113 ? 53.13780  4.93420   -64.42625 1.000 38.24458  ?  113 GLY B O   1 
ATOM   4687 N  N   . GLY B 1 114 ? 53.06334  3.94172   -62.40007 1.000 40.74314  ?  114 GLY B N   1 
ATOM   4688 C  CA  . GLY B 1 114 ? 52.77071  2.62890   -62.92424 1.000 33.61098  ?  114 GLY B CA  1 
ATOM   4689 C  C   . GLY B 1 114 ? 51.55909  1.99957   -62.26441 1.000 37.75860  ?  114 GLY B C   1 
ATOM   4690 O  O   . GLY B 1 114 ? 51.15961  2.35908   -61.15638 1.000 40.93348  ?  114 GLY B O   1 
ATOM   4691 N  N   . ALA B 1 115 ? 50.97395  1.04369   -62.98213 1.000 35.34009  ?  115 ALA B N   1 
ATOM   4692 C  CA  . ALA B 1 115 ? 49.86712  0.22635   -62.49113 1.000 27.10240  ?  115 ALA B CA  1 
ATOM   4693 C  C   . ALA B 1 115 ? 50.39008  -1.19994  -62.35657 1.000 21.80556  ?  115 ALA B C   1 
ATOM   4694 O  O   . ALA B 1 115 ? 50.51953  -1.92020  -63.35049 1.000 17.48215  ?  115 ALA B O   1 
ATOM   4695 C  CB  . ALA B 1 115 ? 48.66756  0.30428   -63.42896 1.000 19.73811  ?  115 ALA B CB  1 
ATOM   4696 N  N   . LEU B 1 116 ? 50.69397  -1.60117  -61.12385 1.000 19.56328  ?  116 LEU B N   1 
ATOM   4697 C  CA  . LEU B 1 116 ? 51.38173  -2.85808  -60.86431 1.000 21.53393  ?  116 LEU B CA  1 
ATOM   4698 C  C   . LEU B 1 116 ? 50.44431  -4.03556  -60.62399 1.000 22.70031  ?  116 LEU B C   1 
ATOM   4699 O  O   . LEU B 1 116 ? 50.92344  -5.16857  -60.50567 1.000 25.35406  ?  116 LEU B O   1 
ATOM   4700 C  CB  . LEU B 1 116 ? 52.31595  -2.70073  -59.65951 1.000 22.23748  ?  116 LEU B CB  1 
ATOM   4701 C  CG  . LEU B 1 116 ? 53.38421  -1.61172  -59.78037 1.000 22.56503  ?  116 LEU B CG  1 
ATOM   4702 C  CD1 . LEU B 1 116 ? 54.23654  -1.55160  -58.52246 1.000 23.45910  ?  116 LEU B CD1 1 
ATOM   4703 C  CD2 . LEU B 1 116 ? 54.25086  -1.84168  -61.00855 1.000 21.81005  ?  116 LEU B CD2 1 
ATOM   4704 N  N   . HIS B 1 117 ? 49.13270  -3.81061  -60.54807 1.000 17.82240  ?  117 HIS B N   1 
ATOM   4705 C  CA  . HIS B 1 117 ? 48.16696  -4.88187  -60.29388 1.000 18.06856  ?  117 HIS B CA  1 
ATOM   4706 C  C   . HIS B 1 117 ? 47.05391  -4.78412  -61.33385 1.000 20.15004  ?  117 HIS B C   1 
ATOM   4707 O  O   . HIS B 1 117 ? 46.04185  -4.11347  -61.11467 1.000 19.12192  ?  117 HIS B O   1 
ATOM   4708 C  CB  . HIS B 1 117 ? 47.62069  -4.80110  -58.87290 1.000 21.56422  ?  117 HIS B CB  1 
ATOM   4709 C  CG  . HIS B 1 117 ? 46.82729  -6.00171  -58.46230 1.000 23.12416  ?  117 HIS B CG  1 
ATOM   4710 N  ND1 . HIS B 1 117 ? 47.25646  -6.87843  -57.48983 1.000 20.21580  ?  117 HIS B ND1 1 
ATOM   4711 C  CD2 . HIS B 1 117 ? 45.63465  -6.47472  -58.89565 1.000 23.50354  ?  117 HIS B CD2 1 
ATOM   4712 C  CE1 . HIS B 1 117 ? 46.36033  -7.83668  -57.33751 1.000 26.40971  ?  117 HIS B CE1 1 
ATOM   4713 N  NE2 . HIS B 1 117 ? 45.36754  -7.61716  -58.18095 1.000 29.59336  ?  117 HIS B NE2 1 
ATOM   4714 N  N   . LEU B 1 118 ? 47.23989  -5.46972  -62.45934 1.000 21.33340  ?  118 LEU B N   1 
ATOM   4715 C  CA  . LEU B 1 118 ? 46.28011  -5.47028  -63.55162 1.000 23.12114  ?  118 LEU B CA  1 
ATOM   4716 C  C   . LEU B 1 118 ? 46.07235  -6.89378  -64.04714 1.000 28.52576  ?  118 LEU B C   1 
ATOM   4717 O  O   . LEU B 1 118 ? 46.92240  -7.76866  -63.86483 1.000 29.62777  ?  118 LEU B O   1 
ATOM   4718 C  CB  . LEU B 1 118 ? 46.74483  -4.58430  -64.71547 1.000 22.54206  ?  118 LEU B CB  1 
ATOM   4719 C  CG  . LEU B 1 118 ? 47.05136  -3.12153  -64.40093 1.000 24.75409  ?  118 LEU B CG  1 
ATOM   4720 C  CD1 . LEU B 1 118 ? 47.57266  -2.41842  -65.64149 1.000 32.55709  ?  118 LEU B CD1 1 
ATOM   4721 C  CD2 . LEU B 1 118 ? 45.81481  -2.42512  -63.86259 1.000 21.03789  ?  118 LEU B CD2 1 
ATOM   4722 N  N   . HIS B 1 119 ? 44.92120  -7.11689  -64.67449 1.000 25.50361  ?  119 HIS B N   1 
ATOM   4723 C  CA  . HIS B 1 119 ? 44.60536  -8.38136  -65.32130 1.000 21.18918  ?  119 HIS B CA  1 
ATOM   4724 C  C   . HIS B 1 119 ? 44.28937  -8.11940  -66.78781 1.000 18.77948  ?  119 HIS B C   1 
ATOM   4725 O  O   . HIS B 1 119 ? 43.55673  -7.18192  -67.11805 1.000 22.94101  ?  119 HIS B O   1 
ATOM   4726 C  CB  . HIS B 1 119 ? 43.43600  -9.08541  -64.62202 1.000 25.61094  ?  119 HIS B CB  1 
ATOM   4727 C  CG  . HIS B 1 119 ? 43.71877  -9.45157  -63.19552 1.000 28.51470  ?  119 HIS B CG  1 
ATOM   4728 N  ND1 . HIS B 1 119 ? 44.16456  -10.70113 -62.82065 1.000 24.72754  ?  119 HIS B ND1 1 
ATOM   4729 C  CD2 . HIS B 1 119 ? 43.62446  -8.72921  -62.05326 1.000 28.01092  ?  119 HIS B CD2 1 
ATOM   4730 C  CE1 . HIS B 1 119 ? 44.32937  -10.73377 -61.50983 1.000 21.69627  ?  119 HIS B CE1 1 
ATOM   4731 N  NE2 . HIS B 1 119 ? 44.00878  -9.54969  -61.01950 1.000 21.68474  ?  119 HIS B NE2 1 
ATOM   4732 N  N   . ASP B 1 120 ? 44.84651  -8.95722  -67.66453 1.000 17.98339  ?  120 ASP B N   1 
ATOM   4733 C  CA  . ASP B 1 120 ? 44.88293  -8.64874  -69.09059 1.000 19.46128  ?  120 ASP B CA  1 
ATOM   4734 C  C   . ASP B 1 120 ? 43.51152  -8.67233  -69.75226 1.000 19.19281  ?  120 ASP B C   1 
ATOM   4735 O  O   . ASP B 1 120 ? 43.33023  -8.01849  -70.78363 1.000 23.45156  ?  120 ASP B O   1 
ATOM   4736 C  CB  . ASP B 1 120 ? 45.82354  -9.61650  -69.81387 1.000 18.83024  ?  120 ASP B CB  1 
ATOM   4737 C  CG  . ASP B 1 120 ? 45.30927  -11.04553 -69.82491 1.000 22.98525  ?  120 ASP B CG  1 
ATOM   4738 O  OD1 . ASP B 1 120 ? 44.54594  -11.43204 -68.91481 1.000 22.36912  ?  120 ASP B OD1 1 
ATOM   4739 O  OD2 . ASP B 1 120 ? 45.68432  -11.79223 -70.75043 1.000 28.75381  -1 120 ASP B OD2 1 
ATOM   4740 N  N   . THR B 1 121 ? 42.54733  -9.40311  -69.20314 1.000 20.90569  ?  121 THR B N   1 
ATOM   4741 C  CA  . THR B 1 121 ? 41.24217  -9.49362  -69.84122 1.000 19.65447  ?  121 THR B CA  1 
ATOM   4742 C  C   . THR B 1 121 ? 40.26703  -8.41768  -69.38383 1.000 20.25692  ?  121 THR B C   1 
ATOM   4743 O  O   . THR B 1 121 ? 39.15467  -8.34974  -69.91642 1.000 19.72814  ?  121 THR B O   1 
ATOM   4744 C  CB  . THR B 1 121 ? 40.62445  -10.87412 -69.59871 1.000 12.03067  ?  121 THR B CB  1 
ATOM   4745 O  OG1 . THR B 1 121 ? 40.84729  -11.27325 -68.24127 1.000 23.63705  ?  121 THR B OG1 1 
ATOM   4746 C  CG2 . THR B 1 121 ? 41.24200  -11.89541 -70.53403 1.000 15.70263  ?  121 THR B CG2 1 
ATOM   4747 N  N   . ALA B 1 122 ? 40.63685  -7.58767  -68.41269 1.000 20.46719  ?  122 ALA B N   1 
ATOM   4748 C  CA  . ALA B 1 122 ? 39.74671  -6.52864  -67.95349 1.000 21.89564  ?  122 ALA B CA  1 
ATOM   4749 C  C   . ALA B 1 122 ? 40.52973  -5.26006  -67.64245 1.000 28.62060  ?  122 ALA B C   1 
ATOM   4750 O  O   . ALA B 1 122 ? 40.27446  -4.58058  -66.64258 1.000 26.74646  ?  122 ALA B O   1 
ATOM   4751 C  CB  . ALA B 1 122 ? 38.93142  -6.98359  -66.74569 1.000 18.47032  ?  122 ALA B CB  1 
ATOM   4752 N  N   . SER B 1 123 ? 41.50116  -4.92724  -68.49267 1.000 29.27525  ?  123 SER B N   1 
ATOM   4753 C  CA  . SER B 1 123 ? 42.25536  -3.68541  -68.37906 1.000 23.00522  ?  123 SER B CA  1 
ATOM   4754 C  C   . SER B 1 123 ? 42.00564  -2.74411  -69.55103 1.000 24.91813  ?  123 SER B C   1 
ATOM   4755 O  O   . SER B 1 123 ? 42.74367  -1.76783  -69.71948 1.000 23.42431  ?  123 SER B O   1 
ATOM   4756 C  CB  . SER B 1 123 ? 43.75068  -3.97912  -68.24583 1.000 27.53850  ?  123 SER B CB  1 
ATOM   4757 O  OG  . SER B 1 123 ? 44.06304  -4.43389  -66.94078 1.000 25.32614  ?  123 SER B OG  1 
ATOM   4758 N  N   . ALA B 1 124 ? 40.98816  -3.01559  -70.36494 1.000 30.50322  ?  124 ALA B N   1 
ATOM   4759 C  CA  . ALA B 1 124 ? 40.56022  -2.11427  -71.42340 1.000 31.59551  ?  124 ALA B CA  1 
ATOM   4760 C  C   . ALA B 1 124 ? 39.04925  -1.95200  -71.34827 1.000 25.41053  ?  124 ALA B C   1 
ATOM   4761 O  O   . ALA B 1 124 ? 38.33760  -2.81776  -70.83259 1.000 24.95862  ?  124 ALA B O   1 
ATOM   4762 C  CB  . ALA B 1 124 ? 40.97177  -2.61985  -72.81285 1.000 27.19289  ?  124 ALA B CB  1 
ATOM   4763 N  N   . ARG B 1 125 ? 38.56569  -0.82481  -71.86559 1.000 28.43947  ?  125 ARG B N   1 
ATOM   4764 C  CA  . ARG B 1 125 ? 37.14670  -0.51049  -71.76508 1.000 43.66539  ?  125 ARG B CA  1 
ATOM   4765 C  C   . ARG B 1 125 ? 36.30333  -1.54262  -72.50267 1.000 34.14473  ?  125 ARG B C   1 
ATOM   4766 O  O   . ARG B 1 125 ? 36.67690  -2.02794  -73.57398 1.000 37.35456  ?  125 ARG B O   1 
ATOM   4767 C  CB  . ARG B 1 125 ? 36.86516  0.88444   -72.32538 1.000 42.40028  ?  125 ARG B CB  1 
ATOM   4768 C  CG  . ARG B 1 125 ? 37.45582  2.02107   -71.51108 1.000 46.89433  ?  125 ARG B CG  1 
ATOM   4769 C  CD  . ARG B 1 125 ? 36.95485  3.36302   -72.01783 1.000 62.80392  ?  125 ARG B CD  1 
ATOM   4770 N  NE  . ARG B 1 125 ? 37.14256  3.50474   -73.45698 1.000 60.97597  ?  125 ARG B NE  1 
ATOM   4771 C  CZ  . ARG B 1 125 ? 38.21788  4.03372   -74.02455 1.000 58.00185  ?  125 ARG B CZ  1 
ATOM   4772 N  NH1 . ARG B 1 125 ? 39.22662  4.49205   -73.30130 1.000 57.85038  ?  125 ARG B NH1 1 
ATOM   4773 N  NH2 . ARG B 1 125 ? 38.28250  4.10519   -75.35115 1.000 46.87700  ?  125 ARG B NH2 1 
ATOM   4774 N  N   . ILE B 1 126 ? 35.15507  -1.87994  -71.90943 1.000 29.66967  ?  126 ILE B N   1 
ATOM   4775 C  CA  . ILE B 1 126 ? 34.18687  -2.74726  -72.57373 1.000 29.98631  ?  126 ILE B CA  1 
ATOM   4776 C  C   . ILE B 1 126 ? 33.70836  -2.11132  -73.87019 1.000 32.05079  ?  126 ILE B C   1 
ATOM   4777 O  O   . ILE B 1 126 ? 33.36476  -2.81409  -74.83145 1.000 30.68106  ?  126 ILE B O   1 
ATOM   4778 C  CB  . ILE B 1 126 ? 33.01163  -3.04808  -71.62099 1.000 27.24149  ?  126 ILE B CB  1 
ATOM   4779 C  CG1 . ILE B 1 126 ? 33.52336  -3.68184  -70.32737 1.000 18.94076  ?  126 ILE B CG1 1 
ATOM   4780 C  CG2 . ILE B 1 126 ? 31.98287  -3.95076  -72.28701 1.000 25.05589  ?  126 ILE B CG2 1 
ATOM   4781 C  CD1 . ILE B 1 126 ? 32.44169  -3.92124  -69.29895 1.000 20.88694  ?  126 ILE B CD1 1 
ATOM   4782 N  N   . ASP B 1 127 ? 33.68353  -0.77597  -73.92016 1.000 31.31915  ?  127 ASP B N   1 
ATOM   4783 C  CA  . ASP B 1 127 ? 33.25605  -0.07591  -75.12531 1.000 36.94144  ?  127 ASP B CA  1 
ATOM   4784 C  C   . ASP B 1 127 ? 34.11979  -0.43649  -76.32491 1.000 37.48918  ?  127 ASP B C   1 
ATOM   4785 O  O   . ASP B 1 127 ? 33.61847  -0.48254  -77.45123 1.000 34.59734  ?  127 ASP B O   1 
ATOM   4786 C  CB  . ASP B 1 127 ? 33.28030  1.43466   -74.89054 1.000 43.32324  ?  127 ASP B CB  1 
ATOM   4787 C  CG  . ASP B 1 127 ? 32.19779  1.89279   -73.93535 1.000 41.31654  ?  127 ASP B CG  1 
ATOM   4788 O  OD1 . ASP B 1 127 ? 31.03372  1.47997   -74.11566 1.000 36.61052  ?  127 ASP B OD1 1 
ATOM   4789 O  OD2 . ASP B 1 127 ? 32.51122  2.66118   -73.00194 1.000 48.30443  -1 127 ASP B OD2 1 
ATOM   4790 N  N   . TRP B 1 128 ? 35.41329  -0.69062  -76.11323 1.000 37.16248  ?  128 TRP B N   1 
ATOM   4791 C  CA  . TRP B 1 128 ? 36.25816  -1.11080  -77.22651 1.000 29.61891  ?  128 TRP B CA  1 
ATOM   4792 C  C   . TRP B 1 128 ? 35.83155  -2.47224  -77.76040 1.000 27.84107  ?  128 TRP B C   1 
ATOM   4793 O  O   . TRP B 1 128 ? 35.81112  -2.68764  -78.97660 1.000 29.70322  ?  128 TRP B O   1 
ATOM   4794 C  CB  . TRP B 1 128 ? 37.72630  -1.14114  -76.80662 1.000 34.81916  ?  128 TRP B CB  1 
ATOM   4795 C  CG  . TRP B 1 128 ? 38.64300  -1.49119  -77.94105 1.000 37.13583  ?  128 TRP B CG  1 
ATOM   4796 C  CD1 . TRP B 1 128 ? 39.20521  -0.62800  -78.83656 1.000 36.19311  ?  128 TRP B CD1 1 
ATOM   4797 C  CD2 . TRP B 1 128 ? 39.09236  -2.80048  -78.31064 1.000 35.75787  ?  128 TRP B CD2 1 
ATOM   4798 N  NE1 . TRP B 1 128 ? 39.98139  -1.31703  -79.73596 1.000 32.07629  ?  128 TRP B NE1 1 
ATOM   4799 C  CE2 . TRP B 1 128 ? 39.92859  -2.65250  -79.43495 1.000 36.78129  ?  128 TRP B CE2 1 
ATOM   4800 C  CE3 . TRP B 1 128 ? 38.87178  -4.08273  -77.79806 1.000 28.72644  ?  128 TRP B CE3 1 
ATOM   4801 C  CZ2 . TRP B 1 128 ? 40.54283  -3.73643  -80.05478 1.000 31.44540  ?  128 TRP B CZ2 1 
ATOM   4802 C  CZ3 . TRP B 1 128 ? 39.48394  -5.15768  -78.41484 1.000 27.65406  ?  128 TRP B CZ3 1 
ATOM   4803 C  CH2 . TRP B 1 128 ? 40.30951  -4.97796  -79.53097 1.000 28.93090  ?  128 TRP B CH2 1 
ATOM   4804 N  N   . ILE B 1 129 ? 35.49761  -3.40672  -76.86796 1.000 28.50970  ?  129 ILE B N   1 
ATOM   4805 C  CA  . ILE B 1 129 ? 35.04237  -4.72222  -77.30953 1.000 27.39221  ?  129 ILE B CA  1 
ATOM   4806 C  C   . ILE B 1 129 ? 33.71643  -4.60712  -78.05101 1.000 26.40376  ?  129 ILE B C   1 
ATOM   4807 O  O   . ILE B 1 129 ? 33.51736  -5.23027  -79.10107 1.000 21.92967  ?  129 ILE B O   1 
ATOM   4808 C  CB  . ILE B 1 129 ? 34.94482  -5.68571  -76.11117 1.000 20.38134  ?  129 ILE B CB  1 
ATOM   4809 C  CG1 . ILE B 1 129 ? 36.34294  -6.11601  -75.66253 1.000 21.62330  ?  129 ILE B CG1 1 
ATOM   4810 C  CG2 . ILE B 1 129 ? 34.09053  -6.89794  -76.45694 1.000 25.20511  ?  129 ILE B CG2 1 
ATOM   4811 C  CD1 . ILE B 1 129 ? 36.34325  -7.22438  -74.63129 1.000 22.16260  ?  129 ILE B CD1 1 
ATOM   4812 N  N   . VAL B 1 130 ? 32.79316  -3.80170  -77.52521 1.000 27.44954  ?  130 VAL B N   1 
ATOM   4813 C  CA  . VAL B 1 130 ? 31.46478  -3.71113  -78.12514 1.000 22.39936  ?  130 VAL B CA  1 
ATOM   4814 C  C   . VAL B 1 130 ? 31.52471  -2.99597  -79.47218 1.000 29.44600  ?  130 VAL B C   1 
ATOM   4815 O  O   . VAL B 1 130 ? 30.91480  -3.43593  -80.45257 1.000 29.74207  ?  130 VAL B O   1 
ATOM   4816 C  CB  . VAL B 1 130 ? 30.48572  -3.01834  -77.16110 1.000 24.43033  ?  130 VAL B CB  1 
ATOM   4817 C  CG1 . VAL B 1 130 ? 29.10266  -2.93659  -77.78458 1.000 23.31954  ?  130 VAL B CG1 1 
ATOM   4818 C  CG2 . VAL B 1 130 ? 30.43185  -3.76205  -75.83480 1.000 29.22945  ?  130 VAL B CG2 1 
ATOM   4819 N  N   . SER B 1 131 ? 32.25393  -1.88233  -79.54384 1.000 37.08454  ?  131 SER B N   1 
ATOM   4820 C  CA  . SER B 1 131 ? 32.25741  -1.05395  -80.74362 1.000 35.28680  ?  131 SER B CA  1 
ATOM   4821 C  C   . SER B 1 131 ? 33.26563  -1.50291  -81.79143 1.000 27.33959  ?  131 SER B C   1 
ATOM   4822 O  O   . SER B 1 131 ? 33.17981  -1.05626  -82.94122 1.000 23.95882  ?  131 SER B O   1 
ATOM   4823 C  CB  . SER B 1 131 ? 32.54041  0.40692   -80.37889 1.000 26.94236  ?  131 SER B CB  1 
ATOM   4824 O  OG  . SER B 1 131 ? 33.89086  0.57821   -79.98838 1.000 29.96202  ?  131 SER B OG  1 
ATOM   4825 N  N   . ASN B 1 132 ? 34.21992  -2.35566  -81.42888 1.000 28.11581  ?  132 ASN B N   1 
ATOM   4826 C  CA  . ASN B 1 132 ? 35.21293  -2.84340  -82.37719 1.000 30.39427  ?  132 ASN B CA  1 
ATOM   4827 C  C   . ASN B 1 132 ? 35.15070  -4.35027  -82.56307 1.000 32.69337  ?  132 ASN B C   1 
ATOM   4828 O  O   . ASN B 1 132 ? 35.02006  -4.82357  -83.69849 1.000 30.70753  ?  132 ASN B O   1 
ATOM   4829 C  CB  . ASN B 1 132 ? 36.62399  -2.41933  -81.92396 1.000 29.88264  ?  132 ASN B CB  1 
ATOM   4830 C  CG  . ASN B 1 132 ? 37.69867  -2.76540  -82.93825 1.000 34.53577  ?  132 ASN B CG  1 
ATOM   4831 O  OD1 . ASN B 1 132 ? 37.86400  -3.92220  -83.32277 1.000 36.06206  ?  132 ASN B OD1 1 
ATOM   4832 N  ND2 . ASN B 1 132 ? 38.43927  -1.75813  -83.37647 1.000 41.04682  ?  132 ASN B ND2 1 
ATOM   4833 N  N   . ALA B 1 133 ? 35.22709  -5.12066  -81.47449 1.000 37.81769  ?  133 ALA B N   1 
ATOM   4834 C  CA  . ALA B 1 133 ? 35.36881  -6.56867  -81.59815 1.000 32.16147  ?  133 ALA B CA  1 
ATOM   4835 C  C   . ALA B 1 133 ? 34.09199  -7.22006  -82.11611 1.000 28.59475  ?  133 ALA B C   1 
ATOM   4836 O  O   . ALA B 1 133 ? 34.14776  -8.08034  -83.00274 1.000 29.89043  ?  133 ALA B O   1 
ATOM   4837 C  CB  . ALA B 1 133 ? 35.77675  -7.17340  -80.25529 1.000 32.58399  ?  133 ALA B CB  1 
ATOM   4838 N  N   . THR B 1 134 ? 32.93319  -6.82667  -81.58618 1.000 27.14444  ?  134 THR B N   1 
ATOM   4839 C  CA  . THR B 1 134 ? 31.67746  -7.41252  -82.04067 1.000 29.14094  ?  134 THR B CA  1 
ATOM   4840 C  C   . THR B 1 134 ? 31.22819  -6.86003  -83.38634 1.000 26.37647  ?  134 THR B C   1 
ATOM   4841 O  O   . THR B 1 134 ? 30.17740  -7.27271  -83.88910 1.000 25.34076  ?  134 THR B O   1 
ATOM   4842 C  CB  . THR B 1 134 ? 30.57151  -7.20500  -81.00179 1.000 22.41804  ?  134 THR B CB  1 
ATOM   4843 O  OG1 . THR B 1 134 ? 30.05499  -5.87488  -81.10688 1.000 21.94184  ?  134 THR B OG1 1 
ATOM   4844 C  CG2 . THR B 1 134 ? 31.11066  -7.42512  -79.59971 1.000 25.31349  ?  134 THR B CG2 1 
ATOM   4845 N  N   . TYR B 1 135 ? 31.98447  -5.93238  -83.96824 1.000 26.50272  ?  135 TYR B N   1 
ATOM   4846 C  CA  . TYR B 1 135 ? 31.78106  -5.50225  -85.34268 1.000 28.74307  ?  135 TYR B CA  1 
ATOM   4847 C  C   . TYR B 1 135 ? 32.69176  -6.22900  -86.32188 1.000 28.40403  ?  135 TYR B C   1 
ATOM   4848 O  O   . TYR B 1 135 ? 32.67737  -5.91105  -87.51495 1.000 31.14454  ?  135 TYR B O   1 
ATOM   4849 C  CB  . TYR B 1 135 ? 31.98632  -3.98907  -85.46128 1.000 21.58159  ?  135 TYR B CB  1 
ATOM   4850 C  CG  . TYR B 1 135 ? 30.75273  -3.19113  -85.10837 1.000 23.68668  ?  135 TYR B CG  1 
ATOM   4851 C  CD1 . TYR B 1 135 ? 29.81636  -2.86269  -86.07964 1.000 27.76094  ?  135 TYR B CD1 1 
ATOM   4852 C  CD2 . TYR B 1 135 ? 30.51736  -2.77558  -83.80454 1.000 25.80726  ?  135 TYR B CD2 1 
ATOM   4853 C  CE1 . TYR B 1 135 ? 28.68357  -2.13768  -85.76488 1.000 25.61338  ?  135 TYR B CE1 1 
ATOM   4854 C  CE2 . TYR B 1 135 ? 29.38574  -2.04927  -83.47958 1.000 24.43031  ?  135 TYR B CE2 1 
ATOM   4855 C  CZ  . TYR B 1 135 ? 28.47348  -1.73363  -84.46448 1.000 24.13640  ?  135 TYR B CZ  1 
ATOM   4856 O  OH  . TYR B 1 135 ? 27.34567  -1.01272  -84.14998 1.000 26.69934  ?  135 TYR B OH  1 
ATOM   4857 N  N   . ARG B 1 136 ? 33.48102  -7.18857  -85.84917 1.000 25.49915  ?  136 ARG B N   1 
ATOM   4858 C  CA  . ARG B 1 136 ? 34.34227  -7.97782  -86.71344 1.000 23.67314  ?  136 ARG B CA  1 
ATOM   4859 C  C   . ARG B 1 136 ? 33.60377  -9.21481  -87.21875 1.000 28.36472  ?  136 ARG B C   1 
ATOM   4860 O  O   . ARG B 1 136 ? 32.53742  -9.58408  -86.72292 1.000 24.34992  ?  136 ARG B O   1 
ATOM   4861 C  CB  . ARG B 1 136 ? 35.61842  -8.38160  -85.97678 1.000 12.38635  ?  136 ARG B CB  1 
ATOM   4862 C  CG  . ARG B 1 136 ? 36.42594  -7.20622  -85.46903 1.000 18.43694  ?  136 ARG B CG  1 
ATOM   4863 C  CD  . ARG B 1 136 ? 37.79553  -7.63379  -84.97935 1.000 17.96990  ?  136 ARG B CD  1 
ATOM   4864 N  NE  . ARG B 1 136 ? 38.53284  -6.50843  -84.41925 1.000 19.76417  ?  136 ARG B NE  1 
ATOM   4865 C  CZ  . ARG B 1 136 ? 39.81132  -6.54510  -84.07112 1.000 25.22613  ?  136 ARG B CZ  1 
ATOM   4866 N  NH1 . ARG B 1 136 ? 40.53886  -7.63979  -84.22427 1.000 26.59983  ?  136 ARG B NH1 1 
ATOM   4867 N  NH2 . ARG B 1 136 ? 40.37475  -5.45479  -83.55902 1.000 30.19955  ?  136 ARG B NH2 1 
ATOM   4868 N  N   . ASP B 1 137 ? 34.18953  -9.85668  -88.22490 1.000 36.08825  ?  137 ASP B N   1 
ATOM   4869 C  CA  . ASP B 1 137 ? 33.59976  -11.04846 -88.80955 1.000 37.28741  ?  137 ASP B CA  1 
ATOM   4870 C  C   . ASP B 1 137 ? 33.79106  -12.25380 -87.89248 1.000 35.61326  ?  137 ASP B C   1 
ATOM   4871 O  O   . ASP B 1 137 ? 34.70311  -12.29975 -87.06168 1.000 32.29110  ?  137 ASP B O   1 
ATOM   4872 C  CB  . ASP B 1 137 ? 34.20443  -11.32915 -90.18629 1.000 38.02485  ?  137 ASP B CB  1 
ATOM   4873 C  CG  . ASP B 1 137 ? 33.74650  -10.33487 -91.23895 1.000 44.26349  ?  137 ASP B CG  1 
ATOM   4874 O  OD1 . ASP B 1 137 ? 32.60275  -9.84166  -91.13858 1.000 29.30067  ?  137 ASP B OD1 1 
ATOM   4875 O  OD2 . ASP B 1 137 ? 34.53006  -10.04774 -92.16854 1.000 44.38797  -1 137 ASP B OD2 1 
ATOM   4876 N  N   . HIS B 1 138 ? 32.89466  -13.23113 -88.05211 1.000 36.15549  ?  138 HIS B N   1 
ATOM   4877 C  CA  . HIS B 1 138 ? 32.90766  -14.50907 -87.34177 1.000 29.49110  ?  138 HIS B CA  1 
ATOM   4878 C  C   . HIS B 1 138 ? 32.61293  -14.36906 -85.85266 1.000 28.76914  ?  138 HIS B C   1 
ATOM   4879 O  O   . HIS B 1 138 ? 32.95165  -15.26235 -85.07081 1.000 29.52719  ?  138 HIS B O   1 
ATOM   4880 C  CB  . HIS B 1 138 ? 34.23907  -15.24887 -87.53437 1.000 28.77294  ?  138 HIS B CB  1 
ATOM   4881 C  CG  . HIS B 1 138 ? 34.64305  -15.40817 -88.96684 1.000 32.65884  ?  138 HIS B CG  1 
ATOM   4882 N  ND1 . HIS B 1 138 ? 34.27014  -16.49405 -89.72929 1.000 40.85316  ?  138 HIS B ND1 1 
ATOM   4883 C  CD2 . HIS B 1 138 ? 35.39309  -14.62156 -89.77438 1.000 32.60612  ?  138 HIS B CD2 1 
ATOM   4884 C  CE1 . HIS B 1 138 ? 34.76991  -16.36793 -90.94572 1.000 42.76613  ?  138 HIS B CE1 1 
ATOM   4885 N  NE2 . HIS B 1 138 ? 35.45523  -15.24009 -90.99950 1.000 34.66413  ?  138 HIS B NE2 1 
ATOM   4886 N  N   . VAL B 1 139 ? 31.98326  -13.27612 -85.43188 1.000 30.06164  ?  139 VAL B N   1 
ATOM   4887 C  CA  . VAL B 1 139 ? 31.65439  -13.05411 -84.02775 1.000 30.69686  ?  139 VAL B CA  1 
ATOM   4888 C  C   . VAL B 1 139 ? 30.19030  -13.41444 -83.80599 1.000 31.70206  ?  139 VAL B C   1 
ATOM   4889 O  O   . VAL B 1 139 ? 29.29423  -12.83488 -84.43233 1.000 29.30490  ?  139 VAL B O   1 
ATOM   4890 C  CB  . VAL B 1 139 ? 31.93909  -11.60521 -83.60472 1.000 27.76438  ?  139 VAL B CB  1 
ATOM   4891 C  CG1 . VAL B 1 139 ? 31.49726  -11.37899 -82.16708 1.000 26.95187  ?  139 VAL B CG1 1 
ATOM   4892 C  CG2 . VAL B 1 139 ? 33.41764  -11.29217 -83.76375 1.000 24.63979  ?  139 VAL B CG2 1 
ATOM   4893 N  N   . TYR B 1 140 ? 29.95065  -14.36362 -82.90658 1.000 27.07489  ?  140 TYR B N   1 
ATOM   4894 C  CA  . TYR B 1 140 ? 28.62057  -14.83739 -82.55963 1.000 25.82476  ?  140 TYR B CA  1 
ATOM   4895 C  C   . TYR B 1 140 ? 28.28965  -14.46170 -81.12044 1.000 25.36957  ?  140 TYR B C   1 
ATOM   4896 O  O   . TYR B 1 140 ? 29.17421  -14.17492 -80.30860 1.000 29.83926  ?  140 TYR B O   1 
ATOM   4897 C  CB  . TYR B 1 140 ? 28.51290  -16.35791 -82.73219 1.000 26.77104  ?  140 TYR B CB  1 
ATOM   4898 C  CG  . TYR B 1 140 ? 28.76948  -16.85636 -84.13783 1.000 31.02041  ?  140 TYR B CG  1 
ATOM   4899 C  CD1 . TYR B 1 140 ? 30.06506  -17.01121 -84.61681 1.000 33.40640  ?  140 TYR B CD1 1 
ATOM   4900 C  CD2 . TYR B 1 140 ? 27.71672  -17.19019 -84.97956 1.000 30.47169  ?  140 TYR B CD2 1 
ATOM   4901 C  CE1 . TYR B 1 140 ? 30.30418  -17.47136 -85.89825 1.000 37.90867  ?  140 TYR B CE1 1 
ATOM   4902 C  CE2 . TYR B 1 140 ? 27.94667  -17.65412 -86.26236 1.000 40.54714  ?  140 TYR B CE2 1 
ATOM   4903 C  CZ  . TYR B 1 140 ? 29.24179  -17.79144 -86.71673 1.000 41.59426  ?  140 TYR B CZ  1 
ATOM   4904 O  OH  . TYR B 1 140 ? 29.47592  -18.25027 -87.99335 1.000 32.46307  ?  140 TYR B OH  1 
ATOM   4905 N  N   . MET B 1 141 ? 26.99487  -14.48568 -80.81062 1.000 23.48243  ?  141 MET B N   1 
ATOM   4906 C  CA  . MET B 1 141 ? 26.49300  -14.14320 -79.48858 1.000 28.80066  ?  141 MET B CA  1 
ATOM   4907 C  C   . MET B 1 141 ? 25.36737  -15.09738 -79.11659 1.000 32.57445  ?  141 MET B C   1 
ATOM   4908 O  O   . MET B 1 141 ? 24.72551  -15.70000 -79.98005 1.000 32.20552  ?  141 MET B O   1 
ATOM   4909 C  CB  . MET B 1 141 ? 25.98726  -12.69554 -79.43121 1.000 22.87657  ?  141 MET B CB  1 
ATOM   4910 C  CG  . MET B 1 141 ? 24.83803  -12.41360 -80.38781 1.000 28.50930  ?  141 MET B CG  1 
ATOM   4911 S  SD  . MET B 1 141 ? 24.12136  -10.77281 -80.18664 1.000 32.74604  ?  141 MET B SD  1 
ATOM   4912 C  CE  . MET B 1 141 ? 23.39153  -10.91733 -78.55847 1.000 24.84277  ?  141 MET B CE  1 
ATOM   4913 N  N   . CYS B 1 142 ? 25.13758  -15.23297 -77.81259 1.000 32.41826  ?  142 CYS B N   1 
ATOM   4914 C  CA  . CYS B 1 142 ? 24.03208  -16.05760 -77.33963 1.000 26.44993  ?  142 CYS B CA  1 
ATOM   4915 C  C   . CYS B 1 142 ? 23.64512  -15.63583 -75.93020 1.000 34.25050  ?  142 CYS B C   1 
ATOM   4916 O  O   . CYS B 1 142 ? 24.48405  -15.18088 -75.15382 1.000 35.86479  ?  142 CYS B O   1 
ATOM   4917 C  CB  . CYS B 1 142 ? 24.38840  -17.54784 -77.35837 1.000 37.75373  ?  142 CYS B CB  1 
ATOM   4918 S  SG  . CYS B 1 142 ? 25.15487  -18.15707 -75.83540 1.000 35.42966  ?  142 CYS B SG  1 
ATOM   4919 N  N   . MET B 1 143 ? 22.36780  -15.80259 -75.60305 1.000 41.91850  ?  143 MET B N   1 
ATOM   4920 C  CA  . MET B 1 143 ? 21.87422  -15.56888 -74.25127 1.000 37.44143  ?  143 MET B CA  1 
ATOM   4921 C  C   . MET B 1 143 ? 21.83610  -16.90131 -73.51268 1.000 33.56055  ?  143 MET B C   1 
ATOM   4922 O  O   . MET B 1 143 ? 21.08472  -17.80445 -73.89566 1.000 39.88046  ?  143 MET B O   1 
ATOM   4923 C  CB  . MET B 1 143 ? 20.49047  -14.91959 -74.27312 1.000 29.51244  ?  143 MET B CB  1 
ATOM   4924 C  CG  . MET B 1 143 ? 20.45090  -13.56583 -74.96588 1.000 40.16238  ?  143 MET B CG  1 
ATOM   4925 S  SD  . MET B 1 143 ? 21.53906  -12.34754 -74.20062 1.000 36.48196  ?  143 MET B SD  1 
ATOM   4926 C  CE  . MET B 1 143 ? 20.77934  -12.17262 -72.58822 1.000 38.71317  ?  143 MET B CE  1 
ATOM   4927 N  N   . ASP B 1 144 ? 22.64405  -17.02385 -72.46115 1.000 32.66744  ?  144 ASP B N   1 
ATOM   4928 C  CA  . ASP B 1 144 ? 22.74096  -18.28172 -71.73731 1.000 32.85621  ?  144 ASP B CA  1 
ATOM   4929 C  C   . ASP B 1 144 ? 21.52678  -18.46760 -70.82717 1.000 36.13556  ?  144 ASP B C   1 
ATOM   4930 O  O   . ASP B 1 144 ? 20.58995  -17.66359 -70.81648 1.000 31.62783  ?  144 ASP B O   1 
ATOM   4931 C  CB  . ASP B 1 144 ? 24.05555  -18.35306 -70.95605 1.000 23.13107  ?  144 ASP B CB  1 
ATOM   4932 C  CG  . ASP B 1 144 ? 24.19719  -17.25089 -69.91287 1.000 24.46697  ?  144 ASP B CG  1 
ATOM   4933 O  OD1 . ASP B 1 144 ? 23.20476  -16.56376 -69.60014 1.000 31.15808  ?  144 ASP B OD1 1 
ATOM   4934 O  OD2 . ASP B 1 144 ? 25.32098  -17.07210 -69.39810 1.000 24.14978  -1 144 ASP B OD2 1 
ATOM   4935 N  N   . GLN B 1 145 ? 21.55009  -19.54488 -70.04053 1.000 36.69527  ?  145 GLN B N   1 
ATOM   4936 C  CA  . GLN B 1 145 ? 20.41922  -19.88196 -69.18555 1.000 31.47353  ?  145 GLN B CA  1 
ATOM   4937 C  C   . GLN B 1 145 ? 20.23490  -18.90522 -68.03156 1.000 31.79602  ?  145 GLN B C   1 
ATOM   4938 O  O   . GLN B 1 145 ? 19.19771  -18.95577 -67.36207 1.000 36.12222  ?  145 GLN B O   1 
ATOM   4939 C  CB  . GLN B 1 145 ? 20.58139  -21.30533 -68.65059 1.000 35.47939  ?  145 GLN B CB  1 
ATOM   4940 C  CG  . GLN B 1 145 ? 20.91806  -22.32213 -69.73233 1.000 44.31378  ?  145 GLN B CG  1 
ATOM   4941 C  CD  . GLN B 1 145 ? 20.33428  -23.69295 -69.45360 1.000 53.24632  ?  145 GLN B CD  1 
ATOM   4942 O  OE1 . GLN B 1 145 ? 20.93561  -24.50860 -68.75426 1.000 57.08936  ?  145 GLN B OE1 1 
ATOM   4943 N  NE2 . GLN B 1 145 ? 19.15413  -23.95423 -70.00421 1.000 40.51032  ?  145 GLN B NE2 1 
ATOM   4944 N  N   . ASP B 1 146 ? 21.20432  -18.02699 -67.78310 1.000 31.93715  ?  146 ASP B N   1 
ATOM   4945 C  CA  . ASP B 1 146 ? 21.09670  -17.00152 -66.75561 1.000 31.10157  ?  146 ASP B CA  1 
ATOM   4946 C  C   . ASP B 1 146 ? 20.75815  -15.63421 -67.33367 1.000 29.19255  ?  146 ASP B C   1 
ATOM   4947 O  O   . ASP B 1 146 ? 20.87444  -14.62789 -66.62650 1.000 33.06804  ?  146 ASP B O   1 
ATOM   4948 C  CB  . ASP B 1 146 ? 22.39509  -16.92674 -65.95105 1.000 34.81225  ?  146 ASP B CB  1 
ATOM   4949 C  CG  . ASP B 1 146 ? 22.73618  -18.24056 -65.27595 1.000 31.25520  ?  146 ASP B CG  1 
ATOM   4950 O  OD1 . ASP B 1 146 ? 21.84485  -18.82093 -64.62072 1.000 29.67248  ?  146 ASP B OD1 1 
ATOM   4951 O  OD2 . ASP B 1 146 ? 23.89155  -18.69719 -65.40817 1.000 24.08943  -1 146 ASP B OD2 1 
ATOM   4952 N  N   . ASN B 1 147 ? 20.34207  -15.58166 -68.60113 1.000 29.54239  ?  147 ASN B N   1 
ATOM   4953 C  CA  . ASN B 1 147 ? 20.02016  -14.33241 -69.29377 1.000 31.79883  ?  147 ASN B CA  1 
ATOM   4954 C  C   . ASN B 1 147 ? 21.21933  -13.38353 -69.30063 1.000 31.80365  ?  147 ASN B C   1 
ATOM   4955 O  O   . ASN B 1 147 ? 21.11963  -12.20584 -68.94898 1.000 35.08990  ?  147 ASN B O   1 
ATOM   4956 C  CB  . ASN B 1 147 ? 18.78402  -13.66589 -68.68520 1.000 28.91217  ?  147 ASN B CB  1 
ATOM   4957 C  CG  . ASN B 1 147 ? 17.88640  -13.04015 -69.73371 1.000 37.40197  ?  147 ASN B CG  1 
ATOM   4958 O  OD1 . ASN B 1 147 ? 18.05314  -13.27576 -70.93117 1.000 38.26693  ?  147 ASN B OD1 1 
ATOM   4959 N  ND2 . ASN B 1 147 ? 16.92137  -12.24559 -69.28813 1.000 44.41911  ?  147 ASN B ND2 1 
ATOM   4960 N  N   . PHE B 1 148 ? 22.36728  -13.91982 -69.70656 1.000 26.71977  ?  148 PHE B N   1 
ATOM   4961 C  CA  . PHE B 1 148 ? 23.60363  -13.16757 -69.86610 1.000 26.65655  ?  148 PHE B CA  1 
ATOM   4962 C  C   . PHE B 1 148 ? 24.11013  -13.35876 -71.28717 1.000 29.76120  ?  148 PHE B C   1 
ATOM   4963 O  O   . PHE B 1 148 ? 24.14933  -14.48933 -71.78677 1.000 30.95776  ?  148 PHE B O   1 
ATOM   4964 C  CB  . PHE B 1 148 ? 24.66846  -13.62488 -68.86393 1.000 24.73079  ?  148 PHE B CB  1 
ATOM   4965 C  CG  . PHE B 1 148 ? 24.56129  -12.96920 -67.51931 1.000 29.68245  ?  148 PHE B CG  1 
ATOM   4966 C  CD1 . PHE B 1 148 ? 25.18120  -11.75550 -67.27830 1.000 30.10742  ?  148 PHE B CD1 1 
ATOM   4967 C  CD2 . PHE B 1 148 ? 23.85354  -13.57045 -66.49260 1.000 33.68329  ?  148 PHE B CD2 1 
ATOM   4968 C  CE1 . PHE B 1 148 ? 25.09301  -11.15038 -66.04146 1.000 35.67725  ?  148 PHE B CE1 1 
ATOM   4969 C  CE2 . PHE B 1 148 ? 23.76080  -12.96860 -65.25158 1.000 36.93336  ?  148 PHE B CE2 1 
ATOM   4970 C  CZ  . PHE B 1 148 ? 24.38173  -11.75647 -65.02619 1.000 37.27930  ?  148 PHE B CZ  1 
ATOM   4971 N  N   . VAL B 1 149 ? 24.48909  -12.26192 -71.93632 1.000 39.43981  ?  149 VAL B N   1 
ATOM   4972 C  CA  . VAL B 1 149 ? 25.01802  -12.33409 -73.29251 1.000 35.52977  ?  149 VAL B CA  1 
ATOM   4973 C  C   . VAL B 1 149 ? 26.44426  -12.86890 -73.24826 1.000 30.35576  ?  149 VAL B C   1 
ATOM   4974 O  O   . VAL B 1 149 ? 27.25657  -12.45427 -72.41518 1.000 29.93548  ?  149 VAL B O   1 
ATOM   4975 C  CB  . VAL B 1 149 ? 24.94871  -10.96152 -73.98422 1.000 31.93747  ?  149 VAL B CB  1 
ATOM   4976 C  CG1 . VAL B 1 149 ? 25.82694  -9.93729  -73.28079 1.000 26.09378  ?  149 VAL B CG1 1 
ATOM   4977 C  CG2 . VAL B 1 149 ? 25.34359  -11.08703 -75.44925 1.000 34.38375  ?  149 VAL B CG2 1 
ATOM   4978 N  N   . ARG B 1 150 ? 26.74198  -13.81322 -74.13135 1.000 21.10890  ?  150 ARG B N   1 
ATOM   4979 C  CA  . ARG B 1 150 ? 28.06922  -14.38883 -74.26869 1.000 21.37821  ?  150 ARG B CA  1 
ATOM   4980 C  C   . ARG B 1 150 ? 28.50456  -14.22456 -75.71436 1.000 24.96186  ?  150 ARG B C   1 
ATOM   4981 O  O   . ARG B 1 150 ? 27.73720  -14.53136 -76.63463 1.000 26.91147  ?  150 ARG B O   1 
ATOM   4982 C  CB  . ARG B 1 150 ? 28.08141  -15.86665 -73.86869 1.000 22.13081  ?  150 ARG B CB  1 
ATOM   4983 C  CG  . ARG B 1 150 ? 27.59203  -16.13433 -72.45528 1.000 26.22487  ?  150 ARG B CG  1 
ATOM   4984 C  CD  . ARG B 1 150 ? 27.39639  -17.62218 -72.21128 1.000 29.95663  ?  150 ARG B CD  1 
ATOM   4985 N  NE  . ARG B 1 150 ? 28.61935  -18.28964 -71.78208 1.000 23.47567  ?  150 ARG B NE  1 
ATOM   4986 C  CZ  . ARG B 1 150 ? 28.87263  -18.64990 -70.53123 1.000 27.04710  ?  150 ARG B CZ  1 
ATOM   4987 N  NH1 . ARG B 1 150 ? 28.00874  -18.41704 -69.55680 1.000 25.76260  ?  150 ARG B NH1 1 
ATOM   4988 N  NH2 . ARG B 1 150 ? 30.01858  -19.26416 -70.25173 1.000 38.35321  ?  150 ARG B NH2 1 
ATOM   4989 N  N   . LEU B 1 151 ? 29.72425  -13.73208 -75.90530 1.000 22.46751  ?  151 LEU B N   1 
ATOM   4990 C  CA  . LEU B 1 151 ? 30.28837  -13.47542 -77.22086 1.000 20.21295  ?  151 LEU B CA  1 
ATOM   4991 C  C   . LEU B 1 151 ? 31.41911  -14.45779 -77.48918 1.000 20.93247  ?  151 LEU B C   1 
ATOM   4992 O  O   . LEU B 1 151 ? 32.19732  -14.78442 -76.58731 1.000 25.35991  ?  151 LEU B O   1 
ATOM   4993 C  CB  . LEU B 1 151 ? 30.80875  -12.03862 -77.32115 1.000 21.62287  ?  151 LEU B CB  1 
ATOM   4994 C  CG  . LEU B 1 151 ? 29.79985  -10.92055 -77.05411 1.000 21.73372  ?  151 LEU B CG  1 
ATOM   4995 C  CD1 . LEU B 1 151 ? 30.52016  -9.61785  -76.76036 1.000 22.57388  ?  151 LEU B CD1 1 
ATOM   4996 C  CD2 . LEU B 1 151 ? 28.85890  -10.75449 -78.23613 1.000 32.44865  ?  151 LEU B CD2 1 
ATOM   4997 N  N   . THR B 1 152 ? 31.50355  -14.93070 -78.72934 1.000 23.80579  ?  152 THR B N   1 
ATOM   4998 C  CA  . THR B 1 152 ? 32.53520  -15.88490 -79.10919 1.000 26.40679  ?  152 THR B CA  1 
ATOM   4999 C  C   . THR B 1 152 ? 32.91593  -15.64795 -80.56331 1.000 26.21046  ?  152 THR B C   1 
ATOM   5000 O  O   . THR B 1 152 ? 32.26286  -14.89038 -81.28286 1.000 26.36921  ?  152 THR B O   1 
ATOM   5001 C  CB  . THR B 1 152 ? 32.07016  -17.33111 -78.90165 1.000 25.86286  ?  152 THR B CB  1 
ATOM   5002 O  OG1 . THR B 1 152 ? 33.19749  -18.21333 -78.96886 1.000 27.27539  ?  152 THR B OG1 1 
ATOM   5003 C  CG2 . THR B 1 152 ? 31.06577  -17.72525 -79.97544 1.000 24.41290  ?  152 THR B CG2 1 
ATOM   5004 N  N   . VAL B 1 153 ? 33.99241  -16.30373 -80.98917 1.000 24.48649  ?  153 VAL B N   1 
ATOM   5005 C  CA  . VAL B 1 153 ? 34.46212  -16.24331 -82.36798 1.000 21.26430  ?  153 VAL B CA  1 
ATOM   5006 C  C   . VAL B 1 153 ? 34.57399  -17.66960 -82.88610 1.000 28.67994  ?  153 VAL B C   1 
ATOM   5007 O  O   . VAL B 1 153 ? 35.25092  -18.50391 -82.27304 1.000 29.66136  ?  153 VAL B O   1 
ATOM   5008 C  CB  . VAL B 1 153 ? 35.81044  -15.51365 -82.48999 1.000 21.46182  ?  153 VAL B CB  1 
ATOM   5009 C  CG1 . VAL B 1 153 ? 36.27257  -15.49797 -83.93464 1.000 23.11149  ?  153 VAL B CG1 1 
ATOM   5010 C  CG2 . VAL B 1 153 ? 35.69874  -14.09642 -81.94903 1.000 25.23192  ?  153 VAL B CG2 1 
ATOM   5011 N  N   . SER B 1 154 ? 33.91137  -17.95009 -84.00716 1.000 34.43265  ?  154 SER B N   1 
ATOM   5012 C  CA  . SER B 1 154 ? 33.94940  -19.27123 -84.62994 1.000 31.55055  ?  154 SER B CA  1 
ATOM   5013 C  C   . SER B 1 154 ? 34.11020  -19.08611 -86.13141 1.000 29.43732  ?  154 SER B C   1 
ATOM   5014 O  O   . SER B 1 154 ? 33.19924  -18.58390 -86.79692 1.000 41.06310  ?  154 SER B O   1 
ATOM   5015 C  CB  . SER B 1 154 ? 32.68645  -20.07238 -84.31310 1.000 41.92805  ?  154 SER B CB  1 
ATOM   5016 O  OG  . SER B 1 154 ? 32.67912  -21.30700 -85.00921 1.000 49.92265  ?  154 SER B OG  1 
ATOM   5017 N  N   . GLY B 1 155 ? 35.26032  -19.49130 -86.66225 1.000 26.72840  ?  155 GLY B N   1 
ATOM   5018 C  CA  . GLY B 1 155 ? 35.51688  -19.39095 -88.08272 1.000 35.37541  ?  155 GLY B CA  1 
ATOM   5019 C  C   . GLY B 1 155 ? 34.97088  -20.51933 -88.92360 1.000 49.82152  ?  155 GLY B C   1 
ATOM   5020 O  O   . GLY B 1 155 ? 35.12705  -20.49750 -90.14731 1.000 51.25776  ?  155 GLY B O   1 
ATOM   5021 N  N   . THR B 1 156 ? 34.32464  -21.50322 -88.30351 1.000 49.27839  ?  156 THR B N   1 
ATOM   5022 C  CA  . THR B 1 156 ? 33.81146  -22.68711 -88.98106 1.000 39.76448  ?  156 THR B CA  1 
ATOM   5023 C  C   . THR B 1 156 ? 32.29017  -22.74737 -88.90095 1.000 34.93807  ?  156 THR B C   1 
ATOM   5024 O  O   . THR B 1 156 ? 31.70492  -23.79248 -88.61144 1.000 39.76443  ?  156 THR B O   1 
ATOM   5025 C  CB  . THR B 1 156 ? 34.43093  -23.95612 -88.39977 1.000 45.98615  ?  156 THR B CB  1 
ATOM   5026 O  OG1 . THR B 1 156 ? 34.17433  -24.01439 -86.98984 1.000 60.16351  ?  156 THR B OG1 1 
ATOM   5027 C  CG2 . THR B 1 156 ? 35.93372  -23.96673 -88.63485 1.000 31.64547  ?  156 THR B CG2 1 
ATOM   5028 N  N   . GLY B 1 157 ? 31.63191  -21.61822 -89.14907 1.000 32.74614  ?  157 GLY B N   1 
ATOM   5029 C  CA  . GLY B 1 157 ? 30.19205  -21.54926 -89.09034 1.000 36.17239  ?  157 GLY B CA  1 
ATOM   5030 C  C   . GLY B 1 157 ? 29.69613  -21.31667 -87.67910 1.000 42.80727  ?  157 GLY B C   1 
ATOM   5031 O  O   . GLY B 1 157 ? 30.44003  -20.86189 -86.80399 1.000 36.41479  ?  157 GLY B O   1 
ATOM   5032 N  N   . PRO B 1 158 ? 28.42282  -21.61483 -87.43428 1.000 51.55206  ?  158 PRO B N   1 
ATOM   5033 C  CA  . PRO B 1 158 ? 27.85940  -21.44104 -86.09131 1.000 50.47188  ?  158 PRO B CA  1 
ATOM   5034 C  C   . PRO B 1 158 ? 28.61886  -22.26731 -85.06975 1.000 49.24175  ?  158 PRO B C   1 
ATOM   5035 O  O   . PRO B 1 158 ? 29.05742  -23.38920 -85.36580 1.000 49.18059  ?  158 PRO B O   1 
ATOM   5036 C  CB  . PRO B 1 158 ? 26.41355  -21.93478 -86.24954 1.000 40.08918  ?  158 PRO B CB  1 
ATOM   5037 C  CG  . PRO B 1 158 ? 26.10787  -21.71620 -87.69396 1.000 38.37755  ?  158 PRO B CG  1 
ATOM   5038 C  CD  . PRO B 1 158 ? 27.39598  -21.99794 -88.41887 1.000 44.36966  ?  158 PRO B CD  1 
ATOM   5039 N  N   . PRO B 1 159 ? 28.80333  -21.73869 -83.86051 1.000 48.78150  ?  159 PRO B N   1 
ATOM   5040 C  CA  . PRO B 1 159 ? 29.59712  -22.44390 -82.84806 1.000 47.67634  ?  159 PRO B CA  1 
ATOM   5041 C  C   . PRO B 1 159 ? 29.01514  -23.80468 -82.49144 1.000 65.56855  ?  159 PRO B C   1 
ATOM   5042 O  O   . PRO B 1 159 ? 27.82308  -24.07367 -82.65907 1.000 62.51021  ?  159 PRO B O   1 
ATOM   5043 C  CB  . PRO B 1 159 ? 29.56090  -21.49153 -81.64812 1.000 40.66229  ?  159 PRO B CB  1 
ATOM   5044 C  CG  . PRO B 1 159 ? 29.39995  -20.14250 -82.26268 1.000 43.35544  ?  159 PRO B CG  1 
ATOM   5045 C  CD  . PRO B 1 159 ? 28.53184  -20.34301 -83.47796 1.000 49.81266  ?  159 PRO B CD  1 
ATOM   5046 N  N   . ALA B 1 160 ? 29.89921  -24.67352 -81.99135 1.000 72.48721  ?  160 ALA B N   1 
ATOM   5047 C  CA  . ALA B 1 160 ? 29.53865  -26.06759 -81.74965 1.000 73.73814  ?  160 ALA B CA  1 
ATOM   5048 C  C   . ALA B 1 160 ? 28.51891  -26.20790 -80.62491 1.000 88.23907  ?  160 ALA B C   1 
ATOM   5049 O  O   . ALA B 1 160 ? 27.62483  -27.05926 -80.69899 1.000 89.88460  ?  160 ALA B O   1 
ATOM   5050 C  CB  . ALA B 1 160 ? 30.79290  -26.88325 -81.43749 1.000 51.47157  ?  160 ALA B CB  1 
ATOM   5051 N  N   . ASN B 1 161 ? 28.64040  -25.39984 -79.57257 1.000 87.13411  ?  161 ASN B N   1 
ATOM   5052 C  CA  . ASN B 1 161 ? 27.73922  -25.53055 -78.43432 1.000 76.97336  ?  161 ASN B CA  1 
ATOM   5053 C  C   . ASN B 1 161 ? 26.30692  -25.21557 -78.84768 1.000 71.43451  ?  161 ASN B C   1 
ATOM   5054 O  O   . ASN B 1 161 ? 26.04940  -24.26703 -79.59414 1.000 69.59078  ?  161 ASN B O   1 
ATOM   5055 C  CB  . ASN B 1 161 ? 28.17417  -24.60685 -77.29404 1.000 64.36812  ?  161 ASN B CB  1 
ATOM   5056 C  CG  . ASN B 1 161 ? 27.35323  -24.81154 -76.02941 1.000 59.73420  ?  161 ASN B CG  1 
ATOM   5057 O  OD1 . ASN B 1 161 ? 26.75522  -25.86847 -75.82456 1.000 44.02463  ?  161 ASN B OD1 1 
ATOM   5058 N  ND2 . ASN B 1 161 ? 27.32323  -23.79605 -75.17397 1.000 69.30535  ?  161 ASN B ND2 1 
ATOM   5059 N  N   . SER B 1 162 ? 25.37203  -26.03180 -78.36539 1.000 60.24870  ?  162 SER B N   1 
ATOM   5060 C  CA  . SER B 1 162 ? 23.95936  -25.84209 -78.64755 1.000 61.19526  ?  162 SER B CA  1 
ATOM   5061 C  C   . SER B 1 162 ? 23.14220  -25.51714 -77.40532 1.000 60.03050  ?  162 SER B C   1 
ATOM   5062 O  O   . SER B 1 162 ? 21.93022  -25.29753 -77.52206 1.000 52.21076  ?  162 SER B O   1 
ATOM   5063 C  CB  . SER B 1 162 ? 23.38253  -27.08907 -79.33206 1.000 62.79008  ?  162 SER B CB  1 
ATOM   5064 O  OG  . SER B 1 162 ? 24.14835  -27.44874 -80.46857 1.000 76.69405  ?  162 SER B OG  1 
ATOM   5065 N  N   . GLY B 1 163 ? 23.76452  -25.47716 -76.22352 1.000 56.84991  ?  163 GLY B N   1 
ATOM   5066 C  CA  . GLY B 1 163 ? 23.05605  -25.08750 -75.01654 1.000 44.31180  ?  163 GLY B CA  1 
ATOM   5067 C  C   . GLY B 1 163 ? 22.49242  -23.68399 -75.07337 1.000 50.46854  ?  163 GLY B C   1 
ATOM   5068 O  O   . GLY B 1 163 ? 21.56540  -23.36377 -74.32211 1.000 44.67670  ?  163 GLY B O   1 
ATOM   5069 N  N   . CYS B 1 164 ? 23.04042  -22.83571 -75.93985 1.000 64.75382  ?  164 CYS B N   1 
ATOM   5070 C  CA  . CYS B 1 164 ? 22.46410  -21.53870 -76.25633 1.000 48.61194  ?  164 CYS B CA  1 
ATOM   5071 C  C   . CYS B 1 164 ? 22.57343  -21.33054 -77.75871 1.000 49.55001  ?  164 CYS B C   1 
ATOM   5072 O  O   . CYS B 1 164 ? 23.59947  -21.65774 -78.36156 1.000 50.10944  ?  164 CYS B O   1 
ATOM   5073 C  CB  . CYS B 1 164 ? 23.16693  -20.40163 -75.50382 1.000 39.36316  ?  164 CYS B CB  1 
ATOM   5074 S  SG  . CYS B 1 164 ? 24.90173  -20.16770 -75.94803 1.000 56.54255  ?  164 CYS B SG  1 
ATOM   5075 N  N   . GLU B 1 165 ? 21.51236  -20.80108 -78.36327 1.000 60.42969  ?  165 GLU B N   1 
ATOM   5076 C  CA  . GLU B 1 165 ? 21.47919  -20.63566 -79.81339 1.000 52.54345  ?  165 GLU B CA  1 
ATOM   5077 C  C   . GLU B 1 165 ? 22.41079  -19.49949 -80.21376 1.000 44.21352  ?  165 GLU B C   1 
ATOM   5078 O  O   . GLU B 1 165 ? 22.12642  -18.32735 -79.94741 1.000 40.47924  ?  165 GLU B O   1 
ATOM   5079 C  CB  . GLU B 1 165 ? 20.05523  -20.36938 -80.29083 1.000 59.61598  ?  165 GLU B CB  1 
ATOM   5080 C  CG  . GLU B 1 165 ? 19.90056  -20.43146 -81.80341 1.000 65.65402  ?  165 GLU B CG  1 
ATOM   5081 C  CD  . GLU B 1 165 ? 18.47838  -20.17579 -82.25937 1.000 82.42895  ?  165 GLU B CD  1 
ATOM   5082 O  OE1 . GLU B 1 165 ? 17.66732  -19.69607 -81.43996 1.000 94.62326  ?  165 GLU B OE1 1 
ATOM   5083 O  OE2 . GLU B 1 165 ? 18.17140  -20.45615 -83.43757 1.000 87.99034  -1 165 GLU B OE2 1 
ATOM   5084 N  N   . TRP B 1 166 ? 23.52375  -19.84419 -80.85519 1.000 48.54104  ?  166 TRP B N   1 
ATOM   5085 C  CA  . TRP B 1 166 ? 24.51745  -18.85490 -81.24911 1.000 43.32166  ?  166 TRP B CA  1 
ATOM   5086 C  C   . TRP B 1 166 ? 24.09243  -18.18275 -82.54894 1.000 40.29622  ?  166 TRP B C   1 
ATOM   5087 O  O   . TRP B 1 166 ? 23.88802  -18.85366 -83.56633 1.000 47.96694  ?  166 TRP B O   1 
ATOM   5088 C  CB  . TRP B 1 166 ? 25.88664  -19.50997 -81.40455 1.000 36.25177  ?  166 TRP B CB  1 
ATOM   5089 C  CG  . TRP B 1 166 ? 26.49763  -19.95887 -80.11346 1.000 35.80259  ?  166 TRP B CG  1 
ATOM   5090 C  CD1 . TRP B 1 166 ? 26.51054  -21.22540 -79.60905 1.000 42.42308  ?  166 TRP B CD1 1 
ATOM   5091 C  CD2 . TRP B 1 166 ? 27.18764  -19.14074 -79.16120 1.000 37.68515  ?  166 TRP B CD2 1 
ATOM   5092 N  NE1 . TRP B 1 166 ? 27.16552  -21.24785 -78.40145 1.000 43.33215  ?  166 TRP B NE1 1 
ATOM   5093 C  CE2 . TRP B 1 166 ? 27.59090  -19.97999 -78.10423 1.000 42.50017  ?  166 TRP B CE2 1 
ATOM   5094 C  CE3 . TRP B 1 166 ? 27.50312  -17.78013 -79.09996 1.000 36.21084  ?  166 TRP B CE3 1 
ATOM   5095 C  CZ2 . TRP B 1 166 ? 28.29226  -19.50352 -76.99867 1.000 44.81344  ?  166 TRP B CZ2 1 
ATOM   5096 C  CZ3 . TRP B 1 166 ? 28.19825  -17.30927 -78.00199 1.000 32.93902  ?  166 TRP B CZ3 1 
ATOM   5097 C  CH2 . TRP B 1 166 ? 28.58602  -18.16845 -76.96664 1.000 35.70958  ?  166 TRP B CH2 1 
ATOM   5098 N  N   . LYS B 1 167 ? 23.96672  -16.85913 -82.51324 1.000 36.67621  ?  167 LYS B N   1 
ATOM   5099 C  CA  . LYS B 1 167 ? 23.59901  -16.05930 -83.67113 1.000 36.03977  ?  167 LYS B CA  1 
ATOM   5100 C  C   . LYS B 1 167 ? 24.65201  -14.98313 -83.87818 1.000 35.75348  ?  167 LYS B C   1 
ATOM   5101 O  O   . LYS B 1 167 ? 25.17381  -14.42632 -82.90865 1.000 35.76395  ?  167 LYS B O   1 
ATOM   5102 C  CB  . LYS B 1 167 ? 22.22118  -15.41299 -83.48671 1.000 36.22125  ?  167 LYS B CB  1 
ATOM   5103 C  CG  . LYS B 1 167 ? 21.12946  -16.38258 -83.06910 1.000 37.98880  ?  167 LYS B CG  1 
ATOM   5104 C  CD  . LYS B 1 167 ? 19.85466  -15.64563 -82.69478 1.000 48.58112  ?  167 LYS B CD  1 
ATOM   5105 C  CE  . LYS B 1 167 ? 18.75791  -16.61235 -82.27987 1.000 60.20836  ?  167 LYS B CE  1 
ATOM   5106 N  NZ  . LYS B 1 167 ? 17.51473  -15.90142 -81.87124 1.000 52.83941  ?  167 LYS B NZ  1 
ATOM   5107 N  N   . LEU B 1 168 ? 24.96707  -14.69755 -85.13973 1.000 33.37328  ?  168 LEU B N   1 
ATOM   5108 C  CA  . LEU B 1 168 ? 25.93585  -13.65220 -85.43944 1.000 31.07040  ?  168 LEU B CA  1 
ATOM   5109 C  C   . LEU B 1 168 ? 25.46089  -12.31831 -84.87770 1.000 33.09251  ?  168 LEU B C   1 
ATOM   5110 O  O   . LEU B 1 168 ? 24.28728  -11.95708 -85.00081 1.000 40.25205  ?  168 LEU B O   1 
ATOM   5111 C  CB  . LEU B 1 168 ? 26.15419  -13.53755 -86.94946 1.000 32.65297  ?  168 LEU B CB  1 
ATOM   5112 C  CG  . LEU B 1 168 ? 26.48690  -14.81737 -87.72002 1.000 34.14301  ?  168 LEU B CG  1 
ATOM   5113 C  CD1 . LEU B 1 168 ? 25.22911  -15.44683 -88.30849 1.000 31.17256  ?  168 LEU B CD1 1 
ATOM   5114 C  CD2 . LEU B 1 168 ? 27.51871  -14.54689 -88.80593 1.000 28.48700  ?  168 LEU B CD2 1 
ATOM   5115 N  N   . VAL B 1 169 ? 26.38339  -11.58786 -84.24454 1.000 34.90239  ?  169 VAL B N   1 
ATOM   5116 C  CA  . VAL B 1 169 ? 26.04159  -10.28097 -83.68874 1.000 35.17676  ?  169 VAL B CA  1 
ATOM   5117 C  C   . VAL B 1 169 ? 25.58593  -9.33778  -84.79138 1.000 37.06236  ?  169 VAL B C   1 
ATOM   5118 O  O   . VAL B 1 169 ? 24.78544  -8.42529  -84.55189 1.000 35.31199  ?  169 VAL B O   1 
ATOM   5119 C  CB  . VAL B 1 169 ? 27.23805  -9.70179  -82.90752 1.000 33.65274  ?  169 VAL B CB  1 
ATOM   5120 C  CG1 . VAL B 1 169 ? 26.81819  -8.46483  -82.12580 1.000 33.05017  ?  169 VAL B CG1 1 
ATOM   5121 C  CG2 . VAL B 1 169 ? 27.82781  -10.75323 -81.98010 1.000 30.67865  ?  169 VAL B CG2 1 
ATOM   5122 N  N   . GLU B 1 170 ? 26.07342  -9.55084  -86.01560 1.000 39.62391  ?  170 GLU B N   1 
ATOM   5123 C  CA  . GLU B 1 170 ? 25.65557  -8.73062  -87.14684 1.000 37.28532  ?  170 GLU B CA  1 
ATOM   5124 C  C   . GLU B 1 170 ? 24.15400  -8.84701  -87.38735 1.000 31.50296  ?  170 GLU B C   1 
ATOM   5125 O  O   . GLU B 1 170 ? 23.46731  -7.83704  -87.57944 1.000 34.50939  ?  170 GLU B O   1 
ATOM   5126 C  CB  . GLU B 1 170 ? 26.44292  -9.14794  -88.39023 1.000 50.76696  ?  170 GLU B CB  1 
ATOM   5127 C  CG  . GLU B 1 170 ? 26.40077  -8.17052  -89.55059 1.000 68.46254  ?  170 GLU B CG  1 
ATOM   5128 C  CD  . GLU B 1 170 ? 27.30793  -8.59819  -90.69230 1.000 50.07456  ?  170 GLU B CD  1 
ATOM   5129 O  OE1 . GLU B 1 170 ? 27.94986  -9.66375  -90.57450 1.000 26.94516  ?  170 GLU B OE1 1 
ATOM   5130 O  OE2 . GLU B 1 170 ? 27.38151  -7.87126  -91.70539 1.000 58.51392  -1 170 GLU B OE2 1 
ATOM   5131 N  N   . THR B 1 171 ? 23.62160  -10.07096 -87.35066 1.000 35.73247  ?  171 THR B N   1 
ATOM   5132 C  CA  . THR B 1 171 ? 22.19850  -10.27858 -87.60923 1.000 43.39940  ?  171 THR B CA  1 
ATOM   5133 C  C   . THR B 1 171 ? 21.33701  -9.65847  -86.51288 1.000 35.39680  ?  171 THR B C   1 
ATOM   5134 O  O   . THR B 1 171 ? 20.34388  -8.97414  -86.79729 1.000 27.97673  ?  171 THR B O   1 
ATOM   5135 C  CB  . THR B 1 171 ? 21.90620  -11.77510 -87.73597 1.000 35.84503  ?  171 THR B CB  1 
ATOM   5136 O  OG1 . THR B 1 171 ? 22.94464  -12.40442 -88.49719 1.000 34.56194  ?  171 THR B OG1 1 
ATOM   5137 C  CG2 . THR B 1 171 ? 20.57253  -12.00144 -88.43155 1.000 25.97455  ?  171 THR B CG2 1 
ATOM   5138 N  N   . GLU B 1 172 ? 21.69855  -9.89787  -85.24957 1.000 34.29046  ?  172 GLU B N   1 
ATOM   5139 C  CA  . GLU B 1 172 ? 20.93097  -9.34342  -84.13922 1.000 38.91486  ?  172 GLU B CA  1 
ATOM   5140 C  C   . GLU B 1 172 ? 20.98210  -7.82168  -84.14466 1.000 36.61343  ?  172 GLU B C   1 
ATOM   5141 O  O   . GLU B 1 172 ? 19.98934  -7.15702  -83.82395 1.000 32.10679  ?  172 GLU B O   1 
ATOM   5142 C  CB  . GLU B 1 172 ? 21.45391  -9.89766  -82.81372 1.000 36.73736  ?  172 GLU B CB  1 
ATOM   5143 C  CG  . GLU B 1 172 ? 21.52611  -11.41604 -82.76480 1.000 31.38805  ?  172 GLU B CG  1 
ATOM   5144 C  CD  . GLU B 1 172 ? 20.16662  -12.07051 -82.91016 1.000 40.03417  ?  172 GLU B CD  1 
ATOM   5145 O  OE1 . GLU B 1 172 ? 19.28408  -11.80953 -82.06505 1.000 42.01546  ?  172 GLU B OE1 1 
ATOM   5146 O  OE2 . GLU B 1 172 ? 19.97820  -12.83976 -83.87594 1.000 52.31742  -1 172 GLU B OE2 1 
ATOM   5147 N  N   . ARG B 1 173 ? 22.13659  -7.25242  -84.49869 1.000 30.55373  ?  173 ARG B N   1 
ATOM   5148 C  CA  . ARG B 1 173 ? 22.23536  -5.80502  -84.64272 1.000 32.21079  ?  173 ARG B CA  1 
ATOM   5149 C  C   . ARG B 1 173 ? 21.35924  -5.30861  -85.78664 1.000 35.35105  ?  173 ARG B C   1 
ATOM   5150 O  O   . ARG B 1 173 ? 20.76460  -4.22763  -85.70105 1.000 31.33677  ?  173 ARG B O   1 
ATOM   5151 C  CB  . ARG B 1 173 ? 23.69472  -5.40301  -84.85966 1.000 23.43554  ?  173 ARG B CB  1 
ATOM   5152 C  CG  . ARG B 1 173 ? 23.92435  -3.90557  -84.91954 1.000 23.44950  ?  173 ARG B CG  1 
ATOM   5153 C  CD  . ARG B 1 173 ? 25.39603  -3.56585  -85.10433 1.000 26.26770  ?  173 ARG B CD  1 
ATOM   5154 N  NE  . ARG B 1 173 ? 26.19770  -3.90291  -83.93389 1.000 26.05852  ?  173 ARG B NE  1 
ATOM   5155 C  CZ  . ARG B 1 173 ? 27.05143  -4.91574  -83.87449 1.000 28.10515  ?  173 ARG B CZ  1 
ATOM   5156 N  NH1 . ARG B 1 173 ? 27.25009  -5.71450  -84.91009 1.000 31.66161  ?  173 ARG B NH1 1 
ATOM   5157 N  NH2 . ARG B 1 173 ? 27.72727  -5.12900  -82.74939 1.000 28.25292  ?  173 ARG B NH2 1 
ATOM   5158 N  N   . ALA B 1 174 ? 21.27397  -6.08273  -86.87080 1.000 34.66063  ?  174 ALA B N   1 
ATOM   5159 C  CA  . ALA B 1 174 ? 20.41412  -5.70358  -87.98674 1.000 32.27983  ?  174 ALA B CA  1 
ATOM   5160 C  C   . ALA B 1 174 ? 18.95132  -5.65482  -87.56211 1.000 38.86490  ?  174 ALA B C   1 
ATOM   5161 O  O   . ALA B 1 174 ? 18.24609  -4.67588  -87.83098 1.000 42.73463  ?  174 ALA B O   1 
ATOM   5162 C  CB  . ALA B 1 174 ? 20.60737  -6.67707  -89.14963 1.000 26.71980  ?  174 ALA B CB  1 
ATOM   5163 N  N   . ASN B 1 175 ? 18.47893  -6.69871  -86.88205 1.000 38.35905  ?  175 ASN B N   1 
ATOM   5164 C  CA  . ASN B 1 175 ? 17.08116  -6.73575  -86.46687 1.000 33.78784  ?  175 ASN B CA  1 
ATOM   5165 C  C   . ASN B 1 175 ? 16.78129  -5.82588  -85.28196 1.000 37.89682  ?  175 ASN B C   1 
ATOM   5166 O  O   . ASN B 1 175 ? 15.60487  -5.64352  -84.94954 1.000 34.20285  ?  175 ASN B O   1 
ATOM   5167 C  CB  . ASN B 1 175 ? 16.66532  -8.16812  -86.12221 1.000 37.18366  ?  175 ASN B CB  1 
ATOM   5168 C  CG  . ASN B 1 175 ? 16.69799  -9.08947  -87.32393 1.000 36.63828  ?  175 ASN B CG  1 
ATOM   5169 O  OD1 . ASN B 1 175 ? 17.68003  -9.79505  -87.55136 1.000 47.56009  ?  175 ASN B OD1 1 
ATOM   5170 N  ND2 . ASN B 1 175 ? 15.62116  -9.08739  -88.10232 1.000 25.14950  ?  175 ASN B ND2 1 
ATOM   5171 N  N   . SER B 1 176 ? 17.80562  -5.24995  -84.64570 1.000 40.29314  ?  176 SER B N   1 
ATOM   5172 C  CA  . SER B 1 176 ? 17.58944  -4.49159  -83.41661 1.000 44.81693  ?  176 SER B CA  1 
ATOM   5173 C  C   . SER B 1 176 ? 16.76412  -3.23215  -83.65259 1.000 41.33085  ?  176 SER B C   1 
ATOM   5174 O  O   . SER B 1 176 ? 16.01242  -2.81314  -82.76500 1.000 36.10202  ?  176 SER B O   1 
ATOM   5175 C  CB  . SER B 1 176 ? 18.93074  -4.12725  -82.78134 1.000 35.26983  ?  176 SER B CB  1 
ATOM   5176 O  OG  . SER B 1 176 ? 19.58127  -3.10267  -83.51193 1.000 35.88513  ?  176 SER B OG  1 
ATOM   5177 N  N   . GLY B 1 177 ? 16.88898  -2.61575  -84.82465 1.000 40.45342  ?  177 GLY B N   1 
ATOM   5178 C  CA  . GLY B 1 177 ? 16.20345  -1.36662  -85.09035 1.000 37.76797  ?  177 GLY B CA  1 
ATOM   5179 C  C   . GLY B 1 177 ? 17.03689  -0.15968  -84.71219 1.000 46.64153  ?  177 GLY B C   1 
ATOM   5180 O  O   . GLY B 1 177 ? 17.42478  0.63112   -85.57760 1.000 44.85538  ?  177 GLY B O   1 
ATOM   5181 N  N   . ASP B 1 178 ? 17.32063  -0.00762  -83.42008 1.000 50.36667  ?  178 ASP B N   1 
ATOM   5182 C  CA  . ASP B 1 178 ? 18.17916  1.06378   -82.91809 1.000 50.39646  ?  178 ASP B CA  1 
ATOM   5183 C  C   . ASP B 1 178 ? 19.52844  0.44120   -82.57251 1.000 41.94854  ?  178 ASP B C   1 
ATOM   5184 O  O   . ASP B 1 178 ? 19.66956  -0.23874  -81.55296 1.000 40.42792  ?  178 ASP B O   1 
ATOM   5185 C  CB  . ASP B 1 178 ? 17.54360  1.75410   -81.71502 1.000 51.73148  ?  178 ASP B CB  1 
ATOM   5186 C  CG  . ASP B 1 178 ? 18.25079  3.04430   -81.33765 1.000 54.24098  ?  178 ASP B CG  1 
ATOM   5187 O  OD1 . ASP B 1 178 ? 19.28488  3.36776   -81.95974 1.000 54.55793  ?  178 ASP B OD1 1 
ATOM   5188 O  OD2 . ASP B 1 178 ? 17.76735  3.73969   -80.41920 1.000 59.47607  -1 178 ASP B OD2 1 
ATOM   5189 N  N   . ILE B 1 179 ? 20.52099  0.67894   -83.43282 1.000 40.94175  ?  179 ILE B N   1 
ATOM   5190 C  CA  . ILE B 1 179 ? 21.82816  0.04803   -83.27167 1.000 36.65772  ?  179 ILE B CA  1 
ATOM   5191 C  C   . ILE B 1 179 ? 22.53685  0.57577   -82.02902 1.000 34.88862  ?  179 ILE B C   1 
ATOM   5192 O  O   . ILE B 1 179 ? 23.21699  -0.17666  -81.31792 1.000 36.30438  ?  179 ILE B O   1 
ATOM   5193 C  CB  . ILE B 1 179 ? 22.66833  0.25616   -84.54462 1.000 36.64898  ?  179 ILE B CB  1 
ATOM   5194 C  CG1 . ILE B 1 179 ? 21.99325  -0.42704  -85.73685 1.000 35.00726  ?  179 ILE B CG1 1 
ATOM   5195 C  CG2 . ILE B 1 179 ? 24.08292  -0.26332  -84.35017 1.000 29.73916  ?  179 ILE B CG2 1 
ATOM   5196 C  CD1 . ILE B 1 179 ? 22.70545  -0.21164  -87.05282 1.000 26.25804  ?  179 ILE B CD1 1 
ATOM   5197 N  N   . ALA B 1 180 ? 22.39655  1.87401   -81.74899 1.000 34.79956  ?  180 ALA B N   1 
ATOM   5198 C  CA  . ALA B 1 180 ? 22.99246  2.43498   -80.54091 1.000 38.63847  ?  180 ALA B CA  1 
ATOM   5199 C  C   . ALA B 1 180 ? 22.41121  1.78511   -79.29263 1.000 36.93748  ?  180 ALA B C   1 
ATOM   5200 O  O   . ALA B 1 180 ? 23.14773  1.44738   -78.35696 1.000 37.15299  ?  180 ALA B O   1 
ATOM   5201 C  CB  . ALA B 1 180 ? 22.78514  3.94890   -80.50622 1.000 35.40363  ?  180 ALA B CB  1 
ATOM   5202 N  N   . ALA B 1 181 ? 21.08993  1.59180   -79.26737 1.000 34.44072  ?  181 ALA B N   1 
ATOM   5203 C  CA  . ALA B 1 181 ? 20.45990  0.91271   -78.14099 1.000 36.06104  ?  181 ALA B CA  1 
ATOM   5204 C  C   . ALA B 1 181 ? 20.94745  -0.52493  -78.02397 1.000 37.04764  ?  181 ALA B C   1 
ATOM   5205 O  O   . ALA B 1 181 ? 21.16371  -1.02474  -76.91600 1.000 38.24183  ?  181 ALA B O   1 
ATOM   5206 C  CB  . ALA B 1 181 ? 18.93885  0.95530   -78.28488 1.000 31.68937  ?  181 ALA B CB  1 
ATOM   5207 N  N   . PHE B 1 182 ? 21.12891  -1.20393  -79.15835 1.000 33.86064  ?  182 PHE B N   1 
ATOM   5208 C  CA  . PHE B 1 182 ? 21.60994  -2.58272  -79.13994 1.000 27.48720  ?  182 PHE B CA  1 
ATOM   5209 C  C   . PHE B 1 182 ? 23.01304  -2.67347  -78.54695 1.000 32.51787  ?  182 PHE B C   1 
ATOM   5210 O  O   . PHE B 1 182 ? 23.29011  -3.53219  -77.69935 1.000 38.59028  ?  182 PHE B O   1 
ATOM   5211 C  CB  . PHE B 1 182 ? 21.57754  -3.15152  -80.55932 1.000 27.35598  ?  182 PHE B CB  1 
ATOM   5212 C  CG  . PHE B 1 182 ? 22.18808  -4.51605  -80.68636 1.000 28.94840  ?  182 PHE B CG  1 
ATOM   5213 C  CD1 . PHE B 1 182 ? 21.47704  -5.64506  -80.31753 1.000 32.61777  ?  182 PHE B CD1 1 
ATOM   5214 C  CD2 . PHE B 1 182 ? 23.46814  -4.67127  -81.19304 1.000 32.32476  ?  182 PHE B CD2 1 
ATOM   5215 C  CE1 . PHE B 1 182 ? 22.03595  -6.90294  -80.43939 1.000 34.67889  ?  182 PHE B CE1 1 
ATOM   5216 C  CE2 . PHE B 1 182 ? 24.03254  -5.92586  -81.31725 1.000 35.18893  ?  182 PHE B CE2 1 
ATOM   5217 C  CZ  . PHE B 1 182 ? 23.31533  -7.04331  -80.94033 1.000 35.60092  ?  182 PHE B CZ  1 
ATOM   5218 N  N   . ASP B 1 183 ? 23.91449  -1.78651  -78.97635 1.000 28.58074  ?  183 ASP B N   1 
ATOM   5219 C  CA  . ASP B 1 183 ? 25.27983  -1.81935  -78.45700 1.000 30.29559  ?  183 ASP B CA  1 
ATOM   5220 C  C   . ASP B 1 183 ? 25.32553  -1.41892  -76.98502 1.000 29.81601  ?  183 ASP B C   1 
ATOM   5221 O  O   . ASP B 1 183 ? 26.09051  -1.99702  -76.19671 1.000 31.56755  ?  183 ASP B O   1 
ATOM   5222 C  CB  . ASP B 1 183 ? 26.18132  -0.91755  -79.29947 1.000 32.86538  ?  183 ASP B CB  1 
ATOM   5223 C  CG  . ASP B 1 183 ? 26.30875  -1.39972  -80.73507 1.000 33.79055  ?  183 ASP B CG  1 
ATOM   5224 O  OD1 . ASP B 1 183 ? 26.09856  -2.60673  -80.98106 1.000 29.79926  ?  183 ASP B OD1 1 
ATOM   5225 O  OD2 . ASP B 1 183 ? 26.62224  -0.57360  -81.61735 1.000 39.09112  -1 183 ASP B OD2 1 
ATOM   5226 N  N   . HIS B 1 184 ? 24.51060  -0.43687  -76.58989 1.000 28.86826  ?  184 HIS B N   1 
ATOM   5227 C  CA  . HIS B 1 184 ? 24.45241  -0.06866  -75.18099 1.000 28.06652  ?  184 HIS B CA  1 
ATOM   5228 C  C   . HIS B 1 184 ? 23.89993  -1.21203  -74.34058 1.000 32.95897  ?  184 HIS B C   1 
ATOM   5229 O  O   . HIS B 1 184 ? 24.34685  -1.42877  -73.21083 1.000 39.98905  ?  184 HIS B O   1 
ATOM   5230 C  CB  . HIS B 1 184 ? 23.61460  1.19422   -74.99107 1.000 37.87234  ?  184 HIS B CB  1 
ATOM   5231 C  CG  . HIS B 1 184 ? 23.76493  1.81344   -73.63654 1.000 37.96587  ?  184 HIS B CG  1 
ATOM   5232 N  ND1 . HIS B 1 184 ? 23.22766  1.25265   -72.49797 1.000 35.16509  ?  184 HIS B ND1 1 
ATOM   5233 C  CD2 . HIS B 1 184 ? 24.40021  2.94027   -73.23670 1.000 50.35274  ?  184 HIS B CD2 1 
ATOM   5234 C  CE1 . HIS B 1 184 ? 23.52227  2.00872   -71.45570 1.000 41.65024  ?  184 HIS B CE1 1 
ATOM   5235 N  NE2 . HIS B 1 184 ? 24.23241  3.03970   -71.87680 1.000 58.93130  ?  184 HIS B NE2 1 
ATOM   5236 N  N   . TRP B 1 185 ? 22.92738  -1.95766  -74.87366 1.000 30.54327  ?  185 TRP B N   1 
ATOM   5237 C  CA  . TRP B 1 185 ? 22.42992  -3.13430  -74.16822 1.000 33.52659  ?  185 TRP B CA  1 
ATOM   5238 C  C   . TRP B 1 185 ? 23.50631  -4.20239  -74.04617 1.000 33.98158  ?  185 TRP B C   1 
ATOM   5239 O  O   . TRP B 1 185 ? 23.57810  -4.90106  -73.03015 1.000 40.59324  ?  185 TRP B O   1 
ATOM   5240 C  CB  . TRP B 1 185 ? 21.20406  -3.71136  -74.87291 1.000 37.01165  ?  185 TRP B CB  1 
ATOM   5241 C  CG  . TRP B 1 185 ? 20.91466  -5.11726  -74.43242 1.000 42.70938  ?  185 TRP B CG  1 
ATOM   5242 C  CD1 . TRP B 1 185 ? 20.14563  -5.50297  -73.37391 1.000 37.04622  ?  185 TRP B CD1 1 
ATOM   5243 C  CD2 . TRP B 1 185 ? 21.41519  -6.32368  -75.02496 1.000 38.98358  ?  185 TRP B CD2 1 
ATOM   5244 N  NE1 . TRP B 1 185 ? 20.12829  -6.87346  -73.27621 1.000 35.56344  ?  185 TRP B NE1 1 
ATOM   5245 C  CE2 . TRP B 1 185 ? 20.90083  -7.40052  -74.27744 1.000 34.68995  ?  185 TRP B CE2 1 
ATOM   5246 C  CE3 . TRP B 1 185 ? 22.24669  -6.59596  -76.11578 1.000 35.47208  ?  185 TRP B CE3 1 
ATOM   5247 C  CZ2 . TRP B 1 185 ? 21.18697  -8.72815  -74.58759 1.000 43.81840  ?  185 TRP B CZ2 1 
ATOM   5248 C  CZ3 . TRP B 1 185 ? 22.53035  -7.91386  -76.42141 1.000 37.26337  ?  185 TRP B CZ3 1 
ATOM   5249 C  CH2 . TRP B 1 185 ? 22.00175  -8.96332  -75.66081 1.000 42.06057  ?  185 TRP B CH2 1 
ATOM   5250 N  N   . LEU B 1 186 ? 24.31450  -4.38325  -75.09251 1.000 30.17729  ?  186 LEU B N   1 
ATOM   5251 C  CA  . LEU B 1 186 ? 25.45554  -5.28916  -74.98818 1.000 32.38246  ?  186 LEU B CA  1 
ATOM   5252 C  C   . LEU B 1 186 ? 26.34686  -4.89342  -73.81813 1.000 27.94010  ?  186 LEU B C   1 
ATOM   5253 O  O   . LEU B 1 186 ? 26.65951  -5.71526  -72.94382 1.000 29.88311  ?  186 LEU B O   1 
ATOM   5254 C  CB  . LEU B 1 186 ? 26.25225  -5.28653  -76.29412 1.000 27.22916  ?  186 LEU B CB  1 
ATOM   5255 C  CG  . LEU B 1 186 ? 25.98418  -6.40915  -77.29656 1.000 31.90735  ?  186 LEU B CG  1 
ATOM   5256 C  CD1 . LEU B 1 186 ? 26.70519  -6.13702  -78.60757 1.000 30.82295  ?  186 LEU B CD1 1 
ATOM   5257 C  CD2 . LEU B 1 186 ? 26.41574  -7.74668  -76.71866 1.000 26.21493  ?  186 LEU B CD2 1 
ATOM   5258 N  N   . LYS B 1 187 ? 26.73648  -3.61832  -73.77027 1.000 26.00360  ?  187 LYS B N   1 
ATOM   5259 C  CA  . LYS B 1 187 ? 27.58491  -3.15723  -72.67596 1.000 23.37171  ?  187 LYS B CA  1 
ATOM   5260 C  C   . LYS B 1 187 ? 26.89124  -3.32935  -71.32828 1.000 25.52519  ?  187 LYS B C   1 
ATOM   5261 O  O   . LYS B 1 187 ? 27.54214  -3.62475  -70.32212 1.000 27.49783  ?  187 LYS B O   1 
ATOM   5262 C  CB  . LYS B 1 187 ? 27.99056  -1.69942  -72.88462 1.000 22.75985  ?  187 LYS B CB  1 
ATOM   5263 C  CG  . LYS B 1 187 ? 29.05442  -1.22836  -71.90241 1.000 24.20044  ?  187 LYS B CG  1 
ATOM   5264 C  CD  . LYS B 1 187 ? 29.12217  0.28593   -71.82910 1.000 28.69486  ?  187 LYS B CD  1 
ATOM   5265 C  CE  . LYS B 1 187 ? 27.83100  0.86835   -71.28276 1.000 34.43781  ?  187 LYS B CE  1 
ATOM   5266 N  NZ  . LYS B 1 187 ? 27.89555  2.35262   -71.18098 1.000 41.49265  ?  187 LYS B NZ  1 
ATOM   5267 N  N   . SER B 1 188 ? 25.56967  -3.14038  -71.28659 1.000 25.42191  ?  188 SER B N   1 
ATOM   5268 C  CA  . SER B 1 188 ? 24.83873  -3.25351  -70.02666 1.000 25.66134  ?  188 SER B CA  1 
ATOM   5269 C  C   . SER B 1 188 ? 24.79957  -4.69388  -69.53114 1.000 29.16887  ?  188 SER B C   1 
ATOM   5270 O  O   . SER B 1 188 ? 25.02511  -4.95783  -68.34293 1.000 31.81844  ?  188 SER B O   1 
ATOM   5271 C  CB  . SER B 1 188 ? 23.42147  -2.70671  -70.19424 1.000 20.51980  ?  188 SER B CB  1 
ATOM   5272 O  OG  . SER B 1 188 ? 23.45131  -1.32653  -70.51138 1.000 35.29774  ?  188 SER B OG  1 
ATOM   5273 N  N   . ASN B 1 189 ? 24.51428  -5.63678  -70.42903 1.000 27.01101  ?  189 ASN B N   1 
ATOM   5274 C  CA  . ASN B 1 189 ? 24.52036  -7.04677  -70.07515 1.000 27.47465  ?  189 ASN B CA  1 
ATOM   5275 C  C   . ASN B 1 189 ? 25.92597  -7.55324  -69.77818 1.000 28.56639  ?  189 ASN B C   1 
ATOM   5276 O  O   . ASN B 1 189 ? 26.06671  -8.61122  -69.15644 1.000 25.78903  ?  189 ASN B O   1 
ATOM   5277 C  CB  . ASN B 1 189 ? 23.88261  -7.86218  -71.20476 1.000 28.59549  ?  189 ASN B CB  1 
ATOM   5278 C  CG  . ASN B 1 189 ? 22.73884  -8.74445  -70.72827 1.000 33.54781  ?  189 ASN B CG  1 
ATOM   5279 O  OD1 . ASN B 1 189 ? 22.90582  -9.95187  -70.57978 1.000 33.75431  ?  189 ASN B OD1 1 
ATOM   5280 N  ND2 . ASN B 1 189 ? 21.57144  -8.14743  -70.49510 1.000 33.35826  ?  189 ASN B ND2 1 
ATOM   5281 N  N   . ILE B 1 190 ? 26.96176  -6.82261  -70.18578 1.000 29.15995  ?  190 ILE B N   1 
ATOM   5282 C  CA  . ILE B 1 190 ? 28.34101  -7.21819  -69.91476 1.000 26.53308  ?  190 ILE B CA  1 
ATOM   5283 C  C   . ILE B 1 190 ? 28.90155  -6.53950  -68.66639 1.000 23.45803  ?  190 ILE B C   1 
ATOM   5284 O  O   . ILE B 1 190 ? 29.59067  -7.17778  -67.87042 1.000 19.64708  ?  190 ILE B O   1 
ATOM   5285 C  CB  . ILE B 1 190 ? 29.22798  -6.93615  -71.14751 1.000 21.49372  ?  190 ILE B CB  1 
ATOM   5286 C  CG1 . ILE B 1 190 ? 28.86904  -7.88496  -72.29162 1.000 19.60141  ?  190 ILE B CG1 1 
ATOM   5287 C  CG2 . ILE B 1 190 ? 30.70253  -7.07416  -70.80000 1.000 16.41475  ?  190 ILE B CG2 1 
ATOM   5288 C  CD1 . ILE B 1 190 ? 29.67349  -7.65235  -73.55139 1.000 18.89590  ?  190 ILE B CD1 1 
ATOM   5289 N  N   . SER B 1 191 ? 28.62297  -5.25384  -68.47178 1.000 22.75205  ?  191 SER B N   1 
ATOM   5290 C  CA  . SER B 1 191 ? 29.28516  -4.47742  -67.43137 1.000 22.48086  ?  191 SER B CA  1 
ATOM   5291 C  C   . SER B 1 191 ? 28.72068  -4.77734  -66.04818 1.000 19.93815  ?  191 SER B C   1 
ATOM   5292 O  O   . SER B 1 191 ? 27.53641  -5.08485  -65.88441 1.000 20.31970  ?  191 SER B O   1 
ATOM   5293 C  CB  . SER B 1 191 ? 29.15877  -2.98061  -67.71314 1.000 22.24835  ?  191 SER B CB  1 
ATOM   5294 O  OG  . SER B 1 191 ? 29.70311  -2.21996  -66.65018 1.000 19.49252  ?  191 SER B OG  1 
ATOM   5295 N  N   . LEU B 1 192 ? 29.59505  -4.67553  -65.04378 1.000 21.65872  ?  192 LEU B N   1 
ATOM   5296 C  CA  . LEU B 1 192 ? 29.19107  -4.82368  -63.65193 1.000 22.88535  ?  192 LEU B CA  1 
ATOM   5297 C  C   . LEU B 1 192 ? 28.56102  -3.56124  -63.08096 1.000 23.30956  ?  192 LEU B C   1 
ATOM   5298 O  O   . LEU B 1 192 ? 27.85896  -3.64233  -62.06719 1.000 18.69948  ?  192 LEU B O   1 
ATOM   5299 C  CB  . LEU B 1 192 ? 30.39349  -5.21145  -62.78586 1.000 20.26786  ?  192 LEU B CB  1 
ATOM   5300 C  CG  . LEU B 1 192 ? 30.77751  -6.68671  -62.65557 1.000 14.44628  ?  192 LEU B CG  1 
ATOM   5301 C  CD1 . LEU B 1 192 ? 31.34197  -7.22978  -63.95788 1.000 18.47342  ?  192 LEU B CD1 1 
ATOM   5302 C  CD2 . LEU B 1 192 ? 31.76869  -6.87344  -61.51479 1.000 8.48865   ?  192 LEU B CD2 1 
ATOM   5303 N  N   . LEU B 1 193 ? 28.79091  -2.40454  -63.70120 1.000 27.93936  ?  193 LEU B N   1 
ATOM   5304 C  CA  . LEU B 1 193 ? 28.34412  -1.12731  -63.16231 1.000 25.82929  ?  193 LEU B CA  1 
ATOM   5305 C  C   . LEU B 1 193 ? 27.02312  -0.66079  -63.76264 1.000 17.56429  ?  193 LEU B C   1 
ATOM   5306 O  O   . LEU B 1 193 ? 26.61335  0.47871   -63.52111 1.000 18.52790  ?  193 LEU B O   1 
ATOM   5307 C  CB  . LEU B 1 193 ? 29.42228  -0.06051  -63.37118 1.000 24.55156  ?  193 LEU B CB  1 
ATOM   5308 C  CG  . LEU B 1 193 ? 29.50620  1.01590   -62.28543 1.000 21.16188  ?  193 LEU B CG  1 
ATOM   5309 C  CD1 . LEU B 1 193 ? 29.89593  0.39463   -60.95336 1.000 22.12504  ?  193 LEU B CD1 1 
ATOM   5310 C  CD2 . LEU B 1 193 ? 30.48069  2.11309   -62.67436 1.000 22.23057  ?  193 LEU B CD2 1 
ATOM   5311 N  N   . THR B 1 194 ? 26.35206  -1.50880  -64.54498 1.000 16.57250  ?  194 THR B N   1 
ATOM   5312 C  CA  . THR B 1 194 ? 25.03316  -1.14830  -65.05481 1.000 18.04443  ?  194 THR B CA  1 
ATOM   5313 C  C   . THR B 1 194 ? 24.05443  -0.92532  -63.91028 1.000 15.08777  ?  194 THR B C   1 
ATOM   5314 O  O   . THR B 1 194 ? 23.24341  0.00724   -63.94522 1.000 20.05940  ?  194 THR B O   1 
ATOM   5315 C  CB  . THR B 1 194 ? 24.52215  -2.23292  -66.00162 1.000 21.12835  ?  194 THR B CB  1 
ATOM   5316 O  OG1 . THR B 1 194 ? 25.47946  -2.43497  -67.04774 1.000 20.94364  ?  194 THR B OG1 1 
ATOM   5317 C  CG2 . THR B 1 194 ? 23.18751  -1.82665  -66.61197 1.000 14.84370  ?  194 THR B CG2 1 
ATOM   5318 N  N   . THR B 1 195 ? 24.12003  -1.76906  -62.88828 1.000 14.81668  ?  195 THR B N   1 
ATOM   5319 C  CA  . THR B 1 195 ? 23.38765  -1.58782  -61.64719 1.000 13.81803  ?  195 THR B CA  1 
ATOM   5320 C  C   . THR B 1 195 ? 24.38360  -1.43169  -60.50679 1.000 16.33847  ?  195 THR B C   1 
ATOM   5321 O  O   . THR B 1 195 ? 25.58557  -1.65483  -60.66818 1.000 20.07447  ?  195 THR B O   1 
ATOM   5322 C  CB  . THR B 1 195 ? 22.44955  -2.76944  -61.37491 1.000 16.37546  ?  195 THR B CB  1 
ATOM   5323 O  OG1 . THR B 1 195 ? 23.21638  -3.97631  -61.27370 1.000 17.14256  ?  195 THR B OG1 1 
ATOM   5324 C  CG2 . THR B 1 195 ? 21.43215  -2.91180  -62.49557 1.000 19.42516  ?  195 THR B CG2 1 
ATOM   5325 N  N   . ASP B 1 196 ? 23.87636  -1.03735  -59.35036 1.000 17.76862  ?  196 ASP B N   1 
ATOM   5326 C  CA  . ASP B 1 196 ? 24.72066  -0.92022  -58.16935 1.000 18.90854  ?  196 ASP B CA  1 
ATOM   5327 C  C   . ASP B 1 196 ? 25.07494  -2.31384  -57.66724 1.000 20.51009  ?  196 ASP B C   1 
ATOM   5328 O  O   . ASP B 1 196 ? 24.19360  -3.00767  -57.14293 1.000 18.93750  ?  196 ASP B O   1 
ATOM   5329 C  CB  . ASP B 1 196 ? 24.00242  -0.11945  -57.08252 1.000 19.90280  ?  196 ASP B CB  1 
ATOM   5330 C  CG  . ASP B 1 196 ? 24.93183  0.31683   -55.96347 1.000 21.86191  ?  196 ASP B CG  1 
ATOM   5331 O  OD1 . ASP B 1 196 ? 26.12951  -0.03593  -56.00453 1.000 18.19417  ?  196 ASP B OD1 1 
ATOM   5332 O  OD2 . ASP B 1 196 ? 24.46309  1.01956   -55.04252 1.000 24.35756  -1 196 ASP B OD2 1 
ATOM   5333 N  N   . PRO B 1 197 ? 26.32481  -2.76785  -57.80490 1.000 24.94710  ?  197 PRO B N   1 
ATOM   5334 C  CA  . PRO B 1 197 ? 26.65322  -4.13615  -57.37175 1.000 18.71569  ?  197 PRO B CA  1 
ATOM   5335 C  C   . PRO B 1 197 ? 26.41710  -4.36999  -55.89218 1.000 15.73621  ?  197 PRO B C   1 
ATOM   5336 O  O   . PRO B 1 197 ? 26.09628  -5.49605  -55.49300 1.000 17.54650  ?  197 PRO B O   1 
ATOM   5337 C  CB  . PRO B 1 197 ? 28.13681  -4.27168  -57.74134 1.000 11.77220  ?  197 PRO B CB  1 
ATOM   5338 C  CG  . PRO B 1 197 ? 28.65095  -2.87539  -57.74299 1.000 12.92262  ?  197 PRO B CG  1 
ATOM   5339 C  CD  . PRO B 1 197 ? 27.51932  -2.02518  -58.24314 1.000 22.00118  ?  197 PRO B CD  1 
ATOM   5340 N  N   . LEU B 1 198 ? 26.55946  -3.33434  -55.06520 1.000 15.10385  ?  198 LEU B N   1 
ATOM   5341 C  CA  . LEU B 1 198 ? 26.32697  -3.46261  -53.63306 1.000 21.46110  ?  198 LEU B CA  1 
ATOM   5342 C  C   . LEU B 1 198 ? 24.85922  -3.68552  -53.29286 1.000 18.55556  ?  198 LEU B C   1 
ATOM   5343 O  O   . LEU B 1 198 ? 24.55393  -4.03939  -52.14833 1.000 16.26654  ?  198 LEU B O   1 
ATOM   5344 C  CB  . LEU B 1 198 ? 26.84725  -2.22006  -52.90337 1.000 23.09629  ?  198 LEU B CB  1 
ATOM   5345 C  CG  . LEU B 1 198 ? 28.36021  -2.07692  -52.69194 1.000 15.56440  ?  198 LEU B CG  1 
ATOM   5346 C  CD1 . LEU B 1 198 ? 29.11805  -1.86400  -53.99795 1.000 18.38997  ?  198 LEU B CD1 1 
ATOM   5347 C  CD2 . LEU B 1 198 ? 28.64637  -0.94288  -51.72696 1.000 14.89483  ?  198 LEU B CD2 1 
ATOM   5348 N  N   . VAL B 1 199 ? 23.95269  -3.48802  -54.24560 1.000 14.80608  ?  199 VAL B N   1 
ATOM   5349 C  CA  . VAL B 1 199 ? 22.52583  -3.70026  -54.04224 1.000 15.45661  ?  199 VAL B CA  1 
ATOM   5350 C  C   . VAL B 1 199 ? 22.03096  -4.92129  -54.81098 1.000 13.85130  ?  199 VAL B C   1 
ATOM   5351 O  O   . VAL B 1 199 ? 21.38054  -5.80015  -54.24469 1.000 16.68435  ?  199 VAL B O   1 
ATOM   5352 C  CB  . VAL B 1 199 ? 21.71870  -2.43957  -54.42678 1.000 12.25257  ?  199 VAL B CB  1 
ATOM   5353 C  CG1 . VAL B 1 199 ? 20.25399  -2.61415  -54.05751 1.000 9.14570   ?  199 VAL B CG1 1 
ATOM   5354 C  CG2 . VAL B 1 199 ? 22.30303  -1.20829  -53.75419 1.000 18.71810  ?  199 VAL B CG2 1 
ATOM   5355 N  N   . THR B 1 200 ? 22.33329  -4.99150  -56.10949 1.000 13.54897  ?  200 THR B N   1 
ATOM   5356 C  CA  . THR B 1 200 ? 21.85545  -6.10125  -56.92669 1.000 17.55012  ?  200 THR B CA  1 
ATOM   5357 C  C   . THR B 1 200 ? 22.60799  -7.39632  -56.65210 1.000 21.38141  ?  200 THR B C   1 
ATOM   5358 O  O   . THR B 1 200 ? 22.07318  -8.47748  -56.92057 1.000 26.55255  ?  200 THR B O   1 
ATOM   5359 C  CB  . THR B 1 200 ? 21.95494  -5.74692  -58.41177 1.000 18.38943  ?  200 THR B CB  1 
ATOM   5360 O  OG1 . THR B 1 200 ? 23.25075  -5.20288  -58.69262 1.000 16.45016  ?  200 THR B OG1 1 
ATOM   5361 C  CG2 . THR B 1 200 ? 20.88316  -4.73214  -58.78780 1.000 11.05264  ?  200 THR B CG2 1 
ATOM   5362 N  N   . TYR B 1 201 ? 23.82960  -7.31520  -56.13246 1.000 18.29488  ?  201 TYR B N   1 
ATOM   5363 C  CA  . TYR B 1 201 ? 24.60692  -8.48738  -55.73131 1.000 16.23219  ?  201 TYR B CA  1 
ATOM   5364 C  C   . TYR B 1 201 ? 25.12268  -8.25160  -54.31801 1.000 17.11371  ?  201 TYR B C   1 
ATOM   5365 O  O   . TYR B 1 201 ? 26.32860  -8.08316  -54.10076 1.000 21.30429  ?  201 TYR B O   1 
ATOM   5366 C  CB  . TYR B 1 201 ? 25.75482  -8.74980  -56.70787 1.000 17.92564  ?  201 TYR B CB  1 
ATOM   5367 C  CG  . TYR B 1 201 ? 25.30887  -8.99526  -58.13521 1.000 18.46346  ?  201 TYR B CG  1 
ATOM   5368 C  CD1 . TYR B 1 201 ? 25.00177  -7.93673  -58.98050 1.000 17.41687  ?  201 TYR B CD1 1 
ATOM   5369 C  CD2 . TYR B 1 201 ? 25.20221  -10.28477 -58.63883 1.000 24.35179  ?  201 TYR B CD2 1 
ATOM   5370 C  CE1 . TYR B 1 201 ? 24.59430  -8.15490  -60.28300 1.000 16.72349  ?  201 TYR B CE1 1 
ATOM   5371 C  CE2 . TYR B 1 201 ? 24.79699  -10.51280 -59.94214 1.000 26.46440  ?  201 TYR B CE2 1 
ATOM   5372 C  CZ  . TYR B 1 201 ? 24.49498  -9.44386  -60.75933 1.000 20.67232  ?  201 TYR B CZ  1 
ATOM   5373 O  OH  . TYR B 1 201 ? 24.09093  -9.66391  -62.05683 1.000 21.77604  ?  201 TYR B OH  1 
ATOM   5374 N  N   . PRO B 1 202 ? 24.21448  -8.23731  -53.31076 1.000 18.10164  ?  202 PRO B N   1 
ATOM   5375 C  CA  . PRO B 1 202 ? 24.56911  -7.82758  -51.94565 1.000 16.80943  ?  202 PRO B CA  1 
ATOM   5376 C  C   . PRO B 1 202 ? 25.21244  -8.93904  -51.11850 1.000 29.75094  ?  202 PRO B C   1 
ATOM   5377 O  O   . PRO B 1 202 ? 24.84643  -9.17365  -49.96576 1.000 38.88540  ?  202 PRO B O   1 
ATOM   5378 C  CB  . PRO B 1 202 ? 23.21806  -7.40146  -51.36514 1.000 12.36811  ?  202 PRO B CB  1 
ATOM   5379 C  CG  . PRO B 1 202 ? 22.25002  -8.32559  -52.02668 1.000 16.67436  ?  202 PRO B CG  1 
ATOM   5380 C  CD  . PRO B 1 202 ? 22.79420  -8.62045  -53.41016 1.000 17.04953  ?  202 PRO B CD  1 
ATOM   5381 N  N   . SER B 1 203 ? 26.17979  -9.62776  -51.71499 1.000 35.27143  ?  203 SER B N   1 
ATOM   5382 C  CA  . SER B 1 203 ? 26.91508  -10.68398 -51.03865 1.000 30.91349  ?  203 SER B CA  1 
ATOM   5383 C  C   . SER B 1 203 ? 28.22892  -10.88673 -51.77298 1.000 35.13860  ?  203 SER B C   1 
ATOM   5384 O  O   . SER B 1 203 ? 28.30115  -10.71719 -52.99280 1.000 38.61107  ?  203 SER B O   1 
ATOM   5385 C  CB  . SER B 1 203 ? 26.11644  -11.99203 -50.99135 1.000 30.89149  ?  203 SER B CB  1 
ATOM   5386 O  OG  . SER B 1 203 ? 26.90679  -13.05495 -50.48935 1.000 41.74116  ?  203 SER B OG  1 
ATOM   5387 N  N   . LEU B 1 204 ? 29.26684  -11.24607 -51.01445 1.000 35.03395  ?  204 LEU B N   1 
ATOM   5388 C  CA  . LEU B 1 204 ? 30.56465  -11.51689 -51.62337 1.000 28.42180  ?  204 LEU B CA  1 
ATOM   5389 C  C   . LEU B 1 204 ? 30.45100  -12.61298 -52.67364 1.000 27.53941  ?  204 LEU B C   1 
ATOM   5390 O  O   . LEU B 1 204 ? 31.00360  -12.49484 -53.77524 1.000 27.28565  ?  204 LEU B O   1 
ATOM   5391 C  CB  . LEU B 1 204 ? 31.57329  -11.89876 -50.53718 1.000 23.20985  ?  204 LEU B CB  1 
ATOM   5392 C  CG  . LEU B 1 204 ? 32.94421  -12.44776 -50.93662 1.000 27.85436  ?  204 LEU B CG  1 
ATOM   5393 C  CD1 . LEU B 1 204 ? 34.01607  -11.87991 -50.02452 1.000 32.71330  ?  204 LEU B CD1 1 
ATOM   5394 C  CD2 . LEU B 1 204 ? 32.95861  -13.96895 -50.87584 1.000 33.68967  ?  204 LEU B CD2 1 
ATOM   5395 N  N   . ASP B 1 205 ? 29.71047  -13.67504 -52.35660 1.000 27.64876  ?  205 ASP B N   1 
ATOM   5396 C  CA  . ASP B 1 205 ? 29.56287  -14.79088 -53.28252 1.000 32.54711  ?  205 ASP B CA  1 
ATOM   5397 C  C   . ASP B 1 205 ? 28.77964  -14.39000 -54.52772 1.000 28.09824  ?  205 ASP B C   1 
ATOM   5398 O  O   . ASP B 1 205 ? 29.14552  -14.77392 -55.64271 1.000 26.02608  ?  205 ASP B O   1 
ATOM   5399 C  CB  . ASP B 1 205 ? 28.89235  -15.95811 -52.56451 1.000 37.37708  ?  205 ASP B CB  1 
ATOM   5400 C  CG  . ASP B 1 205 ? 29.57482  -16.29325 -51.25414 1.000 44.21326  ?  205 ASP B CG  1 
ATOM   5401 O  OD1 . ASP B 1 205 ? 30.80490  -16.51308 -51.26620 1.000 38.62206  ?  205 ASP B OD1 1 
ATOM   5402 O  OD2 . ASP B 1 205 ? 28.88852  -16.31867 -50.21094 1.000 54.49814  -1 205 ASP B OD2 1 
ATOM   5403 N  N   . LYS B 1 206 ? 27.70578  -13.61390 -54.36408 1.000 25.11308  ?  206 LYS B N   1 
ATOM   5404 C  CA  . LYS B 1 206 ? 26.89903  -13.21627 -55.51577 1.000 22.57329  ?  206 LYS B CA  1 
ATOM   5405 C  C   . LYS B 1 206 ? 27.68677  -12.31334 -56.46080 1.000 26.88081  ?  206 LYS B C   1 
ATOM   5406 O  O   . LYS B 1 206 ? 27.66438  -12.50100 -57.68507 1.000 29.69087  ?  206 LYS B O   1 
ATOM   5407 C  CB  . LYS B 1 206 ? 25.62143  -12.52123 -55.04223 1.000 20.25336  ?  206 LYS B CB  1 
ATOM   5408 C  CG  . LYS B 1 206 ? 24.77334  -13.36045 -54.09758 1.000 23.42794  ?  206 LYS B CG  1 
ATOM   5409 C  CD  . LYS B 1 206 ? 23.59746  -12.56733 -53.54839 1.000 22.47188  ?  206 LYS B CD  1 
ATOM   5410 C  CE  . LYS B 1 206 ? 22.85582  -13.35117 -52.47555 1.000 16.20860  ?  206 LYS B CE  1 
ATOM   5411 N  NZ  . LYS B 1 206 ? 21.78856  -12.53907 -51.82741 1.000 9.99611   ?  206 LYS B NZ  1 
ATOM   5412 N  N   . VAL B 1 207 ? 28.39486  -11.32474 -55.91085 1.000 25.97899  ?  207 VAL B N   1 
ATOM   5413 C  CA  . VAL B 1 207 ? 29.15595  -10.41881 -56.76393 1.000 24.10701  ?  207 VAL B CA  1 
ATOM   5414 C  C   . VAL B 1 207 ? 30.35033  -11.13711 -57.38680 1.000 24.41328  ?  207 VAL B C   1 
ATOM   5415 O  O   . VAL B 1 207 ? 30.73683  -10.83979 -58.52466 1.000 20.93670  ?  207 VAL B O   1 
ATOM   5416 C  CB  . VAL B 1 207 ? 29.57136  -9.15889  -55.97764 1.000 26.15176  ?  207 VAL B CB  1 
ATOM   5417 C  CG1 . VAL B 1 207 ? 30.59414  -9.48903  -54.89960 1.000 28.79207  ?  207 VAL B CG1 1 
ATOM   5418 C  CG2 . VAL B 1 207 ? 30.09385  -8.08644  -56.92462 1.000 28.46236  ?  207 VAL B CG2 1 
ATOM   5419 N  N   . TRP B 1 208 ? 30.94556  -12.10036 -56.67672 1.000 24.02718  ?  208 TRP B N   1 
ATOM   5420 C  CA  . TRP B 1 208 ? 31.99865  -12.90353 -57.29042 1.000 24.23050  ?  208 TRP B CA  1 
ATOM   5421 C  C   . TRP B 1 208 ? 31.44586  -13.76848 -58.41689 1.000 26.06193  ?  208 TRP B C   1 
ATOM   5422 O  O   . TRP B 1 208 ? 32.11958  -13.98282 -59.43408 1.000 29.29342  ?  208 TRP B O   1 
ATOM   5423 C  CB  . TRP B 1 208 ? 32.69147  -13.76066 -56.23415 1.000 18.40697  ?  208 TRP B CB  1 
ATOM   5424 C  CG  . TRP B 1 208 ? 33.95956  -13.15077 -55.74935 1.000 14.79610  ?  208 TRP B CG  1 
ATOM   5425 C  CD1 . TRP B 1 208 ? 34.14598  -12.45136 -54.59447 1.000 19.20716  ?  208 TRP B CD1 1 
ATOM   5426 C  CD2 . TRP B 1 208 ? 35.22433  -13.16626 -56.41958 1.000 18.73726  ?  208 TRP B CD2 1 
ATOM   5427 N  NE1 . TRP B 1 208 ? 35.45368  -12.03737 -54.49831 1.000 25.43996  ?  208 TRP B NE1 1 
ATOM   5428 C  CE2 . TRP B 1 208 ? 36.13624  -12.46392 -55.60719 1.000 18.40732  ?  208 TRP B CE2 1 
ATOM   5429 C  CE3 . TRP B 1 208 ? 35.67524  -13.71037 -57.62575 1.000 19.91733  ?  208 TRP B CE3 1 
ATOM   5430 C  CZ2 . TRP B 1 208 ? 37.47197  -12.29134 -55.96181 1.000 13.26725  ?  208 TRP B CZ2 1 
ATOM   5431 C  CZ3 . TRP B 1 208 ? 37.00125  -13.53841 -57.97598 1.000 19.90327  ?  208 TRP B CZ3 1 
ATOM   5432 C  CH2 . TRP B 1 208 ? 37.88393  -12.83476 -57.14724 1.000 17.62904  ?  208 TRP B CH2 1 
ATOM   5433 N  N   . GLY B 1 209 ? 30.22459  -14.27873 -58.25007 1.000 15.24386  ?  209 GLY B N   1 
ATOM   5434 C  CA  . GLY B 1 209 ? 29.57303  -14.97894 -59.34141 1.000 17.04429  ?  209 GLY B CA  1 
ATOM   5435 C  C   . GLY B 1 209 ? 29.35706  -14.08448 -60.54459 1.000 20.64245  ?  209 GLY B C   1 
ATOM   5436 O  O   . GLY B 1 209 ? 29.55034  -14.50694 -61.68434 1.000 21.06412  ?  209 GLY B O   1 
ATOM   5437 N  N   . ARG B 1 210 ? 28.96328  -12.83125 -60.30461 1.000 23.48742  ?  210 ARG B N   1 
ATOM   5438 C  CA  . ARG B 1 210 ? 28.82039  -11.87831 -61.40513 1.000 23.29776  ?  210 ARG B CA  1 
ATOM   5439 C  C   . ARG B 1 210 ? 30.15750  -11.61810 -62.09380 1.000 19.71460  ?  210 ARG B C   1 
ATOM   5440 O  O   . ARG B 1 210 ? 30.22137  -11.50640 -63.32281 1.000 17.10058  ?  210 ARG B O   1 
ATOM   5441 C  CB  . ARG B 1 210 ? 28.22063  -10.56623 -60.90022 1.000 23.21262  ?  210 ARG B CB  1 
ATOM   5442 C  CG  . ARG B 1 210 ? 28.03373  -9.52385  -61.99436 1.000 20.31876  ?  210 ARG B CG  1 
ATOM   5443 C  CD  . ARG B 1 210 ? 27.12923  -10.05737 -63.09241 1.000 27.73380  ?  210 ARG B CD  1 
ATOM   5444 N  NE  . ARG B 1 210 ? 27.04492  -9.16000  -64.23818 1.000 27.78270  ?  210 ARG B NE  1 
ATOM   5445 C  CZ  . ARG B 1 210 ? 27.75367  -9.29671  -65.35068 1.000 28.22230  ?  210 ARG B CZ  1 
ATOM   5446 N  NH1 . ARG B 1 210 ? 28.63111  -10.27670 -65.49601 1.000 23.72950  ?  210 ARG B NH1 1 
ATOM   5447 N  NH2 . ARG B 1 210 ? 27.56924  -8.43523  -66.34671 1.000 26.00202  ?  210 ARG B NH2 1 
ATOM   5448 N  N   . PHE B 1 211 ? 31.23177  -11.50069 -61.31188 1.000 19.21852  ?  211 PHE B N   1 
ATOM   5449 C  CA  . PHE B 1 211 ? 32.56643  -11.28853 -61.87124 1.000 18.82973  ?  211 PHE B CA  1 
ATOM   5450 C  C   . PHE B 1 211 ? 32.97971  -12.45440 -62.76966 1.000 21.75225  ?  211 PHE B C   1 
ATOM   5451 O  O   . PHE B 1 211 ? 33.42832  -12.26102 -63.91283 1.000 18.45482  ?  211 PHE B O   1 
ATOM   5452 C  CB  . PHE B 1 211 ? 33.55373  -11.10502 -60.71622 1.000 21.23644  ?  211 PHE B CB  1 
ATOM   5453 C  CG  . PHE B 1 211 ? 34.82164  -10.39380 -61.08576 1.000 22.21289  ?  211 PHE B CG  1 
ATOM   5454 C  CD1 . PHE B 1 211 ? 34.79608  -9.25063  -61.86419 1.000 22.35562  ?  211 PHE B CD1 1 
ATOM   5455 C  CD2 . PHE B 1 211 ? 36.04107  -10.84805 -60.60939 1.000 17.43347  ?  211 PHE B CD2 1 
ATOM   5456 C  CE1 . PHE B 1 211 ? 35.96872  -8.59086  -62.18682 1.000 19.42212  ?  211 PHE B CE1 1 
ATOM   5457 C  CE2 . PHE B 1 211 ? 37.21318  -10.19244 -60.92312 1.000 17.67390  ?  211 PHE B CE2 1 
ATOM   5458 C  CZ  . PHE B 1 211 ? 37.17752  -9.06132  -61.71263 1.000 18.86202  ?  211 PHE B CZ  1 
ATOM   5459 N  N   . ASP B 1 212 ? 32.81963  -13.68115 -62.26573 1.000 19.87461  ?  212 ASP B N   1 
ATOM   5460 C  CA  . ASP B 1 212 ? 33.14613  -14.86138 -63.05991 1.000 21.67416  ?  212 ASP B CA  1 
ATOM   5461 C  C   . ASP B 1 212 ? 32.24599  -14.96732 -64.28505 1.000 22.92861  ?  212 ASP B C   1 
ATOM   5462 O  O   . ASP B 1 212 ? 32.68658  -15.40973 -65.35311 1.000 22.79020  ?  212 ASP B O   1 
ATOM   5463 C  CB  . ASP B 1 212 ? 33.03964  -16.11774 -62.19619 1.000 24.03528  ?  212 ASP B CB  1 
ATOM   5464 C  CG  . ASP B 1 212 ? 34.15660  -16.21757 -61.17529 1.000 24.85747  ?  212 ASP B CG  1 
ATOM   5465 O  OD1 . ASP B 1 212 ? 35.33429  -16.06948 -61.56573 1.000 25.88084  ?  212 ASP B OD1 1 
ATOM   5466 O  OD2 . ASP B 1 212 ? 33.85779  -16.43651 -59.98239 1.000 24.36541  -1 212 ASP B OD2 1 
ATOM   5467 N  N   . LYS B 1 213 ? 30.97937  -14.56595 -64.14880 1.000 17.35400  ?  213 LYS B N   1 
ATOM   5468 C  CA  . LYS B 1 213 ? 30.07339  -14.54696 -65.29026 1.000 15.18667  ?  213 LYS B CA  1 
ATOM   5469 C  C   . LYS B 1 213 ? 30.55014  -13.56712 -66.35073 1.000 17.23673  ?  213 LYS B C   1 
ATOM   5470 O  O   . LYS B 1 213 ? 30.47907  -13.85792 -67.54502 1.000 19.93534  ?  213 LYS B O   1 
ATOM   5471 C  CB  . LYS B 1 213 ? 28.66068  -14.19260 -64.82814 1.000 22.56949  ?  213 LYS B CB  1 
ATOM   5472 C  CG  . LYS B 1 213 ? 27.66401  -13.99201 -65.95710 1.000 27.61110  ?  213 LYS B CG  1 
ATOM   5473 C  CD  . LYS B 1 213 ? 27.39750  -15.28733 -66.70542 1.000 23.96950  ?  213 LYS B CD  1 
ATOM   5474 C  CE  . LYS B 1 213 ? 26.67025  -16.29017 -65.82745 1.000 19.52425  ?  213 LYS B CE  1 
ATOM   5475 N  NZ  . LYS B 1 213 ? 26.35479  -17.54233 -66.56671 1.000 22.95673  ?  213 LYS B NZ  1 
ATOM   5476 N  N   . HIS B 1 214 ? 31.03256  -12.39800 -65.92924 1.000 22.14411  ?  214 HIS B N   1 
ATOM   5477 C  CA  . HIS B 1 214 ? 31.59942  -11.42704 -66.86239 1.000 20.60151  ?  214 HIS B CA  1 
ATOM   5478 C  C   . HIS B 1 214 ? 32.77330  -12.02882 -67.62864 1.000 22.26544  ?  214 HIS B C   1 
ATOM   5479 O  O   . HIS B 1 214 ? 32.86856  -11.90863 -68.86358 1.000 26.19104  ?  214 HIS B O   1 
ATOM   5480 C  CB  . HIS B 1 214 ? 32.03025  -10.18334 -66.08076 1.000 13.48526  ?  214 HIS B CB  1 
ATOM   5481 C  CG  . HIS B 1 214 ? 32.78669  -9.17680  -66.88860 1.000 13.73013  ?  214 HIS B CG  1 
ATOM   5482 N  ND1 . HIS B 1 214 ? 32.17520  -8.33497  -67.79186 1.000 18.82219  ?  214 HIS B ND1 1 
ATOM   5483 C  CD2 . HIS B 1 214 ? 34.10268  -8.85878  -66.90931 1.000 16.09856  ?  214 HIS B CD2 1 
ATOM   5484 C  CE1 . HIS B 1 214 ? 33.08292  -7.54898  -68.34230 1.000 22.32346  ?  214 HIS B CE1 1 
ATOM   5485 N  NE2 . HIS B 1 214 ? 34.26127  -7.84778  -67.82563 1.000 21.33239  ?  214 HIS B NE2 1 
ATOM   5486 N  N   . PHE B 1 215 ? 33.67354  -12.69878 -66.90549 1.000 18.05077  ?  215 PHE B N   1 
ATOM   5487 C  CA  . PHE B 1 215 ? 34.82024  -13.31358 -67.56936 1.000 18.85297  ?  215 PHE B CA  1 
ATOM   5488 C  C   . PHE B 1 215 ? 34.38627  -14.40443 -68.54408 1.000 21.05012  ?  215 PHE B C   1 
ATOM   5489 O  O   . PHE B 1 215 ? 34.93230  -14.50910 -69.64843 1.000 19.27225  ?  215 PHE B O   1 
ATOM   5490 C  CB  . PHE B 1 215 ? 35.80272  -13.85994 -66.53705 1.000 21.67817  ?  215 PHE B CB  1 
ATOM   5491 C  CG  . PHE B 1 215 ? 36.65525  -12.80037 -65.91187 1.000 18.86936  ?  215 PHE B CG  1 
ATOM   5492 C  CD1 . PHE B 1 215 ? 37.68271  -12.20986 -66.62808 1.000 16.27986  ?  215 PHE B CD1 1 
ATOM   5493 C  CD2 . PHE B 1 215 ? 36.42157  -12.38136 -64.61740 1.000 22.34775  ?  215 PHE B CD2 1 
ATOM   5494 C  CE1 . PHE B 1 215 ? 38.46523  -11.22641 -66.05965 1.000 16.98168  ?  215 PHE B CE1 1 
ATOM   5495 C  CE2 . PHE B 1 215 ? 37.19993  -11.40155 -64.04558 1.000 20.87085  ?  215 PHE B CE2 1 
ATOM   5496 C  CZ  . PHE B 1 215 ? 38.22365  -10.82204 -64.76556 1.000 18.06352  ?  215 PHE B CZ  1 
ATOM   5497 N  N   . SER B 1 216 ? 33.40574  -15.22559 -68.15957 1.000 23.89875  ?  216 SER B N   1 
ATOM   5498 C  CA  . SER B 1 216 ? 32.92672  -16.26187 -69.07118 1.000 25.77048  ?  216 SER B CA  1 
ATOM   5499 C  C   . SER B 1 216 ? 32.18945  -15.66255 -70.26393 1.000 26.70260  ?  216 SER B C   1 
ATOM   5500 O  O   . SER B 1 216 ? 32.18596  -16.25457 -71.34970 1.000 27.93368  ?  216 SER B O   1 
ATOM   5501 C  CB  . SER B 1 216 ? 32.02846  -17.25268 -68.32816 1.000 22.96355  ?  216 SER B CB  1 
ATOM   5502 O  OG  . SER B 1 216 ? 30.82339  -16.64263 -67.90124 1.000 26.15137  ?  216 SER B OG  1 
ATOM   5503 N  N   . GLN B 1 217 ? 31.55578  -14.50142 -70.07853 1.000 22.70003  ?  217 GLN B N   1 
ATOM   5504 C  CA  . GLN B 1 217 ? 30.92193  -13.80240 -71.19105 1.000 18.39985  ?  217 GLN B CA  1 
ATOM   5505 C  C   . GLN B 1 217 ? 31.95427  -13.38385 -72.22481 1.000 22.94354  ?  217 GLN B C   1 
ATOM   5506 O  O   . GLN B 1 217 ? 31.75162  -13.55850 -73.43197 1.000 25.67324  ?  217 GLN B O   1 
ATOM   5507 C  CB  . GLN B 1 217 ? 30.16738  -12.57071 -70.68511 1.000 12.35543  ?  217 GLN B CB  1 
ATOM   5508 C  CG  . GLN B 1 217 ? 28.90593  -12.84890 -69.89554 1.000 18.11183  ?  217 GLN B CG  1 
ATOM   5509 C  CD  . GLN B 1 217 ? 28.28129  -11.57654 -69.34883 1.000 24.48220  ?  217 GLN B CD  1 
ATOM   5510 O  OE1 . GLN B 1 217 ? 28.85704  -10.90760 -68.49037 1.000 19.14540  ?  217 GLN B OE1 1 
ATOM   5511 N  NE2 . GLN B 1 217 ? 27.10234  -11.23135 -69.85239 1.000 26.35865  ?  217 GLN B NE2 1 
ATOM   5512 N  N   . LEU B 1 218 ? 33.07045  -12.82125 -71.76747 1.000 22.86515  ?  218 LEU B N   1 
ATOM   5513 C  CA  . LEU B 1 218 ? 34.04820  -12.28072 -72.70687 1.000 20.87795  ?  218 LEU B CA  1 
ATOM   5514 C  C   . LEU B 1 218 ? 35.12299  -13.28056 -73.13133 1.000 25.00171  ?  218 LEU B C   1 
ATOM   5515 O  O   . LEU B 1 218 ? 35.92419  -12.95743 -74.01782 1.000 22.87584  ?  218 LEU B O   1 
ATOM   5516 C  CB  . LEU B 1 218 ? 34.71000  -11.03466 -72.11178 1.000 19.54248  ?  218 LEU B CB  1 
ATOM   5517 C  CG  . LEU B 1 218 ? 33.75818  -9.85052  -71.93226 1.000 18.35203  ?  218 LEU B CG  1 
ATOM   5518 C  CD1 . LEU B 1 218 ? 34.47623  -8.67659  -71.29246 1.000 15.49713  ?  218 LEU B CD1 1 
ATOM   5519 C  CD2 . LEU B 1 218 ? 33.14509  -9.44835  -73.26805 1.000 20.42676  ?  218 LEU B CD2 1 
ATOM   5520 N  N   . ARG B 1 219 ? 35.15310  -14.47853 -72.53769 1.000 26.64955  ?  219 ARG B N   1 
ATOM   5521 C  CA  . ARG B 1 219 ? 36.23972  -15.42196 -72.79904 1.000 25.03888  ?  219 ARG B CA  1 
ATOM   5522 C  C   . ARG B 1 219 ? 36.29892  -15.84076 -74.26367 1.000 21.91269  ?  219 ARG B C   1 
ATOM   5523 O  O   . ARG B 1 219 ? 37.38082  -15.89069 -74.86109 1.000 15.37812  ?  219 ARG B O   1 
ATOM   5524 C  CB  . ARG B 1 219 ? 36.07971  -16.65101 -71.90478 1.000 30.25665  ?  219 ARG B CB  1 
ATOM   5525 C  CG  . ARG B 1 219 ? 37.10837  -17.74540 -72.14826 1.000 31.93914  ?  219 ARG B CG  1 
ATOM   5526 C  CD  . ARG B 1 219 ? 36.73424  -19.01426 -71.39861 1.000 47.06910  ?  219 ARG B CD  1 
ATOM   5527 N  NE  . ARG B 1 219 ? 37.85273  -19.94261 -71.28749 1.000 69.47463  ?  219 ARG B NE  1 
ATOM   5528 C  CZ  . ARG B 1 219 ? 37.80090  -21.10172 -70.64522 1.000 70.00079  ?  219 ARG B CZ  1 
ATOM   5529 N  NH1 . ARG B 1 219 ? 36.69070  -21.51740 -70.05774 1.000 68.91332  ?  219 ARG B NH1 1 
ATOM   5530 N  NH2 . ARG B 1 219 ? 38.89077  -21.86191 -70.58875 1.000 57.08778  ?  219 ARG B NH2 1 
ATOM   5531 N  N   . GLY B 1 220 ? 35.14618  -16.15964 -74.85600 1.000 26.25613  ?  220 GLY B N   1 
ATOM   5532 C  CA  . GLY B 1 220 ? 35.14724  -16.71397 -76.20176 1.000 27.52750  ?  220 GLY B CA  1 
ATOM   5533 C  C   . GLY B 1 220 ? 35.69510  -15.75389 -77.24025 1.000 27.40258  ?  220 GLY B C   1 
ATOM   5534 O  O   . GLY B 1 220 ? 36.42573  -16.15646 -78.14937 1.000 19.62317  ?  220 GLY B O   1 
ATOM   5535 N  N   . ILE B 1 221 ? 35.34965  -14.47553 -77.12348 1.000 28.26044  ?  221 ILE B N   1 
ATOM   5536 C  CA  . ILE B 1 221 ? 35.78052  -13.50078 -78.11496 1.000 21.18502  ?  221 ILE B CA  1 
ATOM   5537 C  C   . ILE B 1 221 ? 37.15387  -12.91891 -77.78354 1.000 20.69061  ?  221 ILE B C   1 
ATOM   5538 O  O   . ILE B 1 221 ? 37.94656  -12.64649 -78.69210 1.000 22.55975  ?  221 ILE B O   1 
ATOM   5539 C  CB  . ILE B 1 221 ? 34.71720  -12.39632 -78.25546 1.000 22.94475  ?  221 ILE B CB  1 
ATOM   5540 C  CG1 . ILE B 1 221 ? 35.14052  -11.35545 -79.29634 1.000 21.61875  ?  221 ILE B CG1 1 
ATOM   5541 C  CG2 . ILE B 1 221 ? 34.43082  -11.74691 -76.90458 1.000 22.19512  ?  221 ILE B CG2 1 
ATOM   5542 C  CD1 . ILE B 1 221 ? 34.06789  -10.33457 -79.60551 1.000 18.64602  ?  221 ILE B CD1 1 
ATOM   5543 N  N   . ILE B 1 222 ? 37.46942  -12.73977 -76.49731 1.000 16.30813  ?  222 ILE B N   1 
ATOM   5544 C  CA  . ILE B 1 222 ? 38.70152  -12.04666 -76.13045 1.000 18.69601  ?  222 ILE B CA  1 
ATOM   5545 C  C   . ILE B 1 222 ? 39.94374  -12.90543 -76.30055 1.000 22.60439  ?  222 ILE B C   1 
ATOM   5546 O  O   . ILE B 1 222 ? 41.05762  -12.36780 -76.28287 1.000 22.24582  ?  222 ILE B O   1 
ATOM   5547 C  CB  . ILE B 1 222 ? 38.61242  -11.52636 -74.68283 1.000 24.42837  ?  222 ILE B CB  1 
ATOM   5548 C  CG1 . ILE B 1 222 ? 39.40999  -10.22923 -74.53907 1.000 22.97816  ?  222 ILE B CG1 1 
ATOM   5549 C  CG2 . ILE B 1 222 ? 39.12117  -12.56983 -73.69773 1.000 24.56324  ?  222 ILE B CG2 1 
ATOM   5550 C  CD1 . ILE B 1 222 ? 39.15232  -9.48719  -73.24734 1.000 22.62730  ?  222 ILE B CD1 1 
ATOM   5551 N  N   . TYR B 1 223 ? 39.79530  -14.21762 -76.47252 1.000 22.02709  ?  223 TYR B N   1 
ATOM   5552 C  CA  . TYR B 1 223 ? 40.94613  -15.09400 -76.65072 1.000 19.91583  ?  223 TYR B CA  1 
ATOM   5553 C  C   . TYR B 1 223 ? 41.27977  -15.36268 -78.11297 1.000 23.89196  ?  223 TYR B C   1 
ATOM   5554 O  O   . TYR B 1 223 ? 42.26467  -16.05654 -78.38823 1.000 22.92057  ?  223 TYR B O   1 
ATOM   5555 C  CB  . TYR B 1 223 ? 40.72429  -16.41826 -75.91489 1.000 17.54270  ?  223 TYR B CB  1 
ATOM   5556 C  CG  . TYR B 1 223 ? 41.17342  -16.37542 -74.47334 1.000 20.44395  ?  223 TYR B CG  1 
ATOM   5557 C  CD1 . TYR B 1 223 ? 42.48136  -16.68742 -74.12563 1.000 21.46266  ?  223 TYR B CD1 1 
ATOM   5558 C  CD2 . TYR B 1 223 ? 40.29490  -16.01248 -73.46203 1.000 20.89475  ?  223 TYR B CD2 1 
ATOM   5559 C  CE1 . TYR B 1 223 ? 42.90015  -16.64587 -72.81018 1.000 20.31742  ?  223 TYR B CE1 1 
ATOM   5560 C  CE2 . TYR B 1 223 ? 40.70425  -15.96806 -72.14339 1.000 23.86796  ?  223 TYR B CE2 1 
ATOM   5561 C  CZ  . TYR B 1 223 ? 42.00765  -16.28527 -71.82344 1.000 22.25750  ?  223 TYR B CZ  1 
ATOM   5562 O  OH  . TYR B 1 223 ? 42.42041  -16.24128 -70.51198 1.000 32.77069  ?  223 TYR B OH  1 
ATOM   5563 N  N   . HIS B 1 224 ? 40.49088  -14.84304 -79.05024 1.000 22.76785  ?  224 HIS B N   1 
ATOM   5564 C  CA  . HIS B 1 224 ? 40.87476  -14.88786 -80.45397 1.000 21.84599  ?  224 HIS B CA  1 
ATOM   5565 C  C   . HIS B 1 224 ? 42.12133  -14.03613 -80.66223 1.000 26.22689  ?  224 HIS B C   1 
ATOM   5566 O  O   . HIS B 1 224 ? 42.23027  -12.93531 -80.11983 1.000 28.16121  ?  224 HIS B O   1 
ATOM   5567 C  CB  . HIS B 1 224 ? 39.72794  -14.38877 -81.33301 1.000 19.71595  ?  224 HIS B CB  1 
ATOM   5568 C  CG  . HIS B 1 224 ? 39.94515  -14.60839 -82.79759 1.000 23.48622  ?  224 HIS B CG  1 
ATOM   5569 N  ND1 . HIS B 1 224 ? 40.75314  -15.61056 -83.28905 1.000 26.29416  ?  224 HIS B ND1 1 
ATOM   5570 C  CD2 . HIS B 1 224 ? 39.45888  -13.95374 -83.87842 1.000 24.07638  ?  224 HIS B CD2 1 
ATOM   5571 C  CE1 . HIS B 1 224 ? 40.75471  -15.56500 -84.60925 1.000 27.48576  ?  224 HIS B CE1 1 
ATOM   5572 N  NE2 . HIS B 1 224 ? 39.97781  -14.56790 -84.99213 1.000 24.83301  ?  224 HIS B NE2 1 
ATOM   5573 N  N   . THR B 1 225 ? 43.06822  -14.55158 -81.44815 1.000 23.48634  ?  225 THR B N   1 
ATOM   5574 C  CA  . THR B 1 225 ? 44.38728  -13.92277 -81.52588 1.000 24.13115  ?  225 THR B CA  1 
ATOM   5575 C  C   . THR B 1 225 ? 44.34746  -12.47411 -82.00213 1.000 27.52136  ?  225 THR B C   1 
ATOM   5576 O  O   . THR B 1 225 ? 44.94184  -11.61477 -81.32637 1.000 31.58348  ?  225 THR B O   1 
ATOM   5577 C  CB  . THR B 1 225 ? 45.31310  -14.77120 -82.40463 1.000 23.06503  ?  225 THR B CB  1 
ATOM   5578 O  OG1 . THR B 1 225 ? 45.50331  -16.05566 -81.79926 1.000 31.81124  ?  225 THR B OG1 1 
ATOM   5579 C  CG2 . THR B 1 225 ? 46.66311  -14.08987 -82.57210 1.000 17.31129  ?  225 THR B CG2 1 
ATOM   5580 N  N   . PRO B 1 226 ? 43.69103  -12.12144 -83.11777 1.000 29.09436  ?  226 PRO B N   1 
ATOM   5581 C  CA  . PRO B 1 226 ? 43.67687  -10.69945 -83.50683 1.000 28.55338  ?  226 PRO B CA  1 
ATOM   5582 C  C   . PRO B 1 226 ? 42.99524  -9.81478  -82.48070 1.000 25.87727  ?  226 PRO B C   1 
ATOM   5583 O  O   . PRO B 1 226 ? 43.50027  -8.72990  -82.15425 1.000 26.89968  ?  226 PRO B O   1 
ATOM   5584 C  CB  . PRO B 1 226 ? 42.91752  -10.70616 -84.84336 1.000 39.02184  ?  226 PRO B CB  1 
ATOM   5585 C  CG  . PRO B 1 226 ? 42.96864  -12.11850 -85.31956 1.000 36.76898  ?  226 PRO B CG  1 
ATOM   5586 C  CD  . PRO B 1 226 ? 42.94070  -12.94760 -84.08081 1.000 29.15247  ?  226 PRO B CD  1 
ATOM   5587 N  N   . ILE B 1 227 ? 41.85966  -10.26870 -81.94769 1.000 23.08734  ?  227 ILE B N   1 
ATOM   5588 C  CA  . ILE B 1 227 ? 41.11349  -9.46828  -80.98512 1.000 25.32104  ?  227 ILE B CA  1 
ATOM   5589 C  C   . ILE B 1 227 ? 41.89710  -9.31944  -79.68729 1.000 25.62494  ?  227 ILE B C   1 
ATOM   5590 O  O   . ILE B 1 227 ? 41.92588  -8.24050  -79.09186 1.000 25.97070  ?  227 ILE B O   1 
ATOM   5591 C  CB  . ILE B 1 227 ? 39.72124  -10.08031 -80.75138 1.000 21.43233  ?  227 ILE B CB  1 
ATOM   5592 C  CG1 . ILE B 1 227 ? 38.98052  -10.21371 -82.08362 1.000 21.20531  ?  227 ILE B CG1 1 
ATOM   5593 C  CG2 . ILE B 1 227 ? 38.91961  -9.22787  -79.78085 1.000 21.93896  ?  227 ILE B CG2 1 
ATOM   5594 C  CD1 . ILE B 1 227 ? 37.55379  -10.69224 -81.95147 1.000 24.94703  ?  227 ILE B CD1 1 
ATOM   5595 N  N   . ARG B 1 228 ? 42.54898  -10.39161 -79.23075 1.000 23.68405  ?  228 ARG B N   1 
ATOM   5596 C  CA  . ARG B 1 228 ? 43.36669  -10.30558 -78.02295 1.000 18.94191  ?  228 ARG B CA  1 
ATOM   5597 C  C   . ARG B 1 228 ? 44.54988  -9.36634  -78.21780 1.000 18.84070  ?  228 ARG B C   1 
ATOM   5598 O  O   . ARG B 1 228 ? 44.87696  -8.57157  -77.32671 1.000 23.77056  ?  228 ARG B O   1 
ATOM   5599 C  CB  . ARG B 1 228 ? 43.85745  -11.69579 -77.61928 1.000 23.00702  ?  228 ARG B CB  1 
ATOM   5600 C  CG  . ARG B 1 228 ? 44.91375  -11.68663 -76.52499 1.000 21.71588  ?  228 ARG B CG  1 
ATOM   5601 C  CD  . ARG B 1 228 ? 44.37331  -11.07899 -75.24090 1.000 29.11100  ?  228 ARG B CD  1 
ATOM   5602 N  NE  . ARG B 1 228 ? 43.36721  -11.92986 -74.61789 1.000 29.14117  ?  228 ARG B NE  1 
ATOM   5603 C  CZ  . ARG B 1 228 ? 43.58997  -12.70387 -73.56502 1.000 26.58209  ?  228 ARG B CZ  1 
ATOM   5604 N  NH1 . ARG B 1 228 ? 44.77066  -12.73857 -72.97068 1.000 23.30391  ?  228 ARG B NH1 1 
ATOM   5605 N  NH2 . ARG B 1 228 ? 42.60184  -13.45825 -73.09394 1.000 25.57886  ?  228 ARG B NH2 1 
ATOM   5606 N  N   . ARG B 1 229 ? 45.21455  -9.45594  -79.37129 1.000 23.18030  ?  229 ARG B N   1 
ATOM   5607 C  CA  . ARG B 1 229 ? 46.34123  -8.57271  -79.65344 1.000 26.25426  ?  229 ARG B CA  1 
ATOM   5608 C  C   . ARG B 1 229 ? 45.90407  -7.11340  -79.63958 1.000 28.68287  ?  229 ARG B C   1 
ATOM   5609 O  O   . ARG B 1 229 ? 46.52314  -6.26555  -78.97824 1.000 34.81426  ?  229 ARG B O   1 
ATOM   5610 C  CB  . ARG B 1 229 ? 46.94988  -8.94850  -81.00435 1.000 27.61734  ?  229 ARG B CB  1 
ATOM   5611 C  CG  . ARG B 1 229 ? 48.04584  -8.03282  -81.50376 1.000 25.33617  ?  229 ARG B CG  1 
ATOM   5612 C  CD  . ARG B 1 229 ? 48.16403  -8.16720  -83.01063 1.000 29.04409  ?  229 ARG B CD  1 
ATOM   5613 N  NE  . ARG B 1 229 ? 46.92897  -7.75469  -83.66741 1.000 28.05472  ?  229 ARG B NE  1 
ATOM   5614 C  CZ  . ARG B 1 229 ? 46.56997  -8.11067  -84.89315 1.000 27.10057  ?  229 ARG B CZ  1 
ATOM   5615 N  NH1 . ARG B 1 229 ? 47.32071  -8.91518  -85.62757 1.000 36.56987  ?  229 ARG B NH1 1 
ATOM   5616 N  NH2 . ARG B 1 229 ? 45.42513  -7.65268  -85.39221 1.000 18.50731  ?  229 ARG B NH2 1 
ATOM   5617 N  N   . ASP B 1 230 ? 44.81269  -6.80844  -80.34479 1.000 24.72189  ?  230 ASP B N   1 
ATOM   5618 C  CA  . ASP B 1 230 ? 44.32132  -5.43732  -80.37933 1.000 25.47063  ?  230 ASP B CA  1 
ATOM   5619 C  C   . ASP B 1 230 ? 43.79890  -4.99107  -79.01813 1.000 28.60296  ?  230 ASP B C   1 
ATOM   5620 O  O   . ASP B 1 230 ? 43.89267  -3.80861  -78.68236 1.000 30.06434  ?  230 ASP B O   1 
ATOM   5621 C  CB  . ASP B 1 230 ? 43.24395  -5.30048  -81.45350 1.000 26.18983  ?  230 ASP B CB  1 
ATOM   5622 C  CG  . ASP B 1 230 ? 43.77500  -5.58019  -82.84670 1.000 27.66019  ?  230 ASP B CG  1 
ATOM   5623 O  OD1 . ASP B 1 230 ? 45.00300  -5.75105  -82.99291 1.000 25.23684  ?  230 ASP B OD1 1 
ATOM   5624 O  OD2 . ASP B 1 230 ? 42.96764  -5.63155  -83.79665 1.000 29.05182  -1 230 ASP B OD2 1 
ATOM   5625 N  N   . TYR B 1 231 ? 43.27436  -5.91822  -78.21265 1.000 29.61296  ?  231 TYR B N   1 
ATOM   5626 C  CA  . TYR B 1 231 ? 42.79155  -5.57212  -76.87966 1.000 21.93530  ?  231 TYR B CA  1 
ATOM   5627 C  C   . TYR B 1 231 ? 43.94239  -5.21989  -75.94600 1.000 21.39715  ?  231 TYR B C   1 
ATOM   5628 O  O   . TYR B 1 231 ? 43.83572  -4.28191  -75.15124 1.000 25.89612  ?  231 TYR B O   1 
ATOM   5629 C  CB  . TYR B 1 231 ? 41.96952  -6.73057  -76.31379 1.000 21.80066  ?  231 TYR B CB  1 
ATOM   5630 C  CG  . TYR B 1 231 ? 41.29795  -6.44658  -74.98924 1.000 20.34058  ?  231 TYR B CG  1 
ATOM   5631 C  CD1 . TYR B 1 231 ? 41.94707  -6.70459  -73.78838 1.000 18.46673  ?  231 TYR B CD1 1 
ATOM   5632 C  CD2 . TYR B 1 231 ? 40.00695  -5.93810  -74.93924 1.000 22.52270  ?  231 TYR B CD2 1 
ATOM   5633 C  CE1 . TYR B 1 231 ? 41.33412  -6.45223  -72.57599 1.000 20.36418  ?  231 TYR B CE1 1 
ATOM   5634 C  CE2 . TYR B 1 231 ? 39.38552  -5.68363  -73.73059 1.000 25.34707  ?  231 TYR B CE2 1 
ATOM   5635 C  CZ  . TYR B 1 231 ? 40.05331  -5.94358  -72.55248 1.000 25.96429  ?  231 TYR B CZ  1 
ATOM   5636 O  OH  . TYR B 1 231 ? 39.43942  -5.69082  -71.34702 1.000 25.06285  ?  231 TYR B OH  1 
ATOM   5637 N  N   . TYR B 1 232 ? 45.04547  -5.96808  -76.01417 1.000 19.48071  ?  232 TYR B N   1 
ATOM   5638 C  CA  . TYR B 1 232 ? 46.22595  -5.60557  -75.23266 1.000 20.20607  ?  232 TYR B CA  1 
ATOM   5639 C  C   . TYR B 1 232 ? 46.79181  -4.26597  -75.69090 1.000 25.56222  ?  232 TYR B C   1 
ATOM   5640 O  O   . TYR B 1 232 ? 47.20331  -3.43096  -74.86771 1.000 25.29526  ?  232 TYR B O   1 
ATOM   5641 C  CB  . TYR B 1 232 ? 47.28313  -6.70340  -75.33944 1.000 17.17569  ?  232 TYR B CB  1 
ATOM   5642 C  CG  . TYR B 1 232 ? 48.56010  -6.39692  -74.59148 1.000 19.55077  ?  232 TYR B CG  1 
ATOM   5643 C  CD1 . TYR B 1 232 ? 48.64442  -6.58578  -73.21851 1.000 20.94083  ?  232 TYR B CD1 1 
ATOM   5644 C  CD2 . TYR B 1 232 ? 49.68256  -5.92259  -75.25804 1.000 19.51605  ?  232 TYR B CD2 1 
ATOM   5645 C  CE1 . TYR B 1 232 ? 49.80843  -6.30839  -72.52925 1.000 18.62629  ?  232 TYR B CE1 1 
ATOM   5646 C  CE2 . TYR B 1 232 ? 50.85213  -5.64236  -74.57671 1.000 20.50879  ?  232 TYR B CE2 1 
ATOM   5647 C  CZ  . TYR B 1 232 ? 50.90868  -5.83748  -73.21229 1.000 19.66331  ?  232 TYR B CZ  1 
ATOM   5648 O  OH  . TYR B 1 232 ? 52.06795  -5.56166  -72.52542 1.000 21.13061  ?  232 TYR B OH  1 
ATOM   5649 N  N   . ARG B 1 233 ? 46.81647  -4.04332  -77.00737 1.000 27.04745  ?  233 ARG B N   1 
ATOM   5650 C  CA  . ARG B 1 233 ? 47.22168  -2.74224  -77.52697 1.000 25.96914  ?  233 ARG B CA  1 
ATOM   5651 C  C   . ARG B 1 233 ? 46.32571  -1.63240  -76.98550 1.000 28.19599  ?  233 ARG B C   1 
ATOM   5652 O  O   . ARG B 1 233 ? 46.80701  -0.55168  -76.62189 1.000 32.24374  ?  233 ARG B O   1 
ATOM   5653 C  CB  . ARG B 1 233 ? 47.19100  -2.77319  -79.05349 1.000 22.46195  ?  233 ARG B CB  1 
ATOM   5654 C  CG  . ARG B 1 233 ? 47.23290  -1.41469  -79.70447 1.000 36.26160  ?  233 ARG B CG  1 
ATOM   5655 C  CD  . ARG B 1 233 ? 48.60817  -0.78796  -79.61639 1.000 27.58264  ?  233 ARG B CD  1 
ATOM   5656 N  NE  . ARG B 1 233 ? 48.57417  0.57957   -80.11654 1.000 39.33175  ?  233 ARG B NE  1 
ATOM   5657 C  CZ  . ARG B 1 233 ? 49.63877  1.27604   -80.48693 1.000 43.80546  ?  233 ARG B CZ  1 
ATOM   5658 N  NH1 . ARG B 1 233 ? 50.85566  0.75728   -80.44264 1.000 45.20216  ?  233 ARG B NH1 1 
ATOM   5659 N  NH2 . ARG B 1 233 ? 49.47655  2.52307   -80.91822 1.000 40.40380  ?  233 ARG B NH2 1 
ATOM   5660 N  N   . GLN B 1 234 ? 45.01822  -1.88969  -76.91557 1.000 26.27851  ?  234 GLN B N   1 
ATOM   5661 C  CA  . GLN B 1 234 ? 44.08070  -0.91278  -76.37315 1.000 26.44376  ?  234 GLN B CA  1 
ATOM   5662 C  C   . GLN B 1 234 ? 44.31546  -0.68481  -74.88567 1.000 25.97725  ?  234 GLN B C   1 
ATOM   5663 O  O   . GLN B 1 234 ? 44.15049  0.43481   -74.39438 1.000 29.45742  ?  234 GLN B O   1 
ATOM   5664 C  CB  . GLN B 1 234 ? 42.64483  -1.37225  -76.62685 1.000 28.56484  ?  234 GLN B CB  1 
ATOM   5665 C  CG  . GLN B 1 234 ? 41.58023  -0.37931  -76.18841 1.000 34.69184  ?  234 GLN B CG  1 
ATOM   5666 C  CD  . GLN B 1 234 ? 41.53791  0.86058   -77.06139 1.000 35.32520  ?  234 GLN B CD  1 
ATOM   5667 O  OE1 . GLN B 1 234 ? 42.11659  0.89063   -78.14812 1.000 37.70072  ?  234 GLN B OE1 1 
ATOM   5668 N  NE2 . GLN B 1 234 ? 40.84608  1.89206   -76.58967 1.000 29.39246  ?  234 GLN B NE2 1 
ATOM   5669 N  N   . ILE B 1 235 ? 44.67654  -1.73832  -74.15061 1.000 25.87652  ?  235 ILE B N   1 
ATOM   5670 C  CA  . ILE B 1 235 ? 45.04957  -1.57687  -72.74638 1.000 28.07347  ?  235 ILE B CA  1 
ATOM   5671 C  C   . ILE B 1 235 ? 46.19355  -0.58315  -72.62647 1.000 22.95100  ?  235 ILE B C   1 
ATOM   5672 O  O   . ILE B 1 235 ? 46.14485  0.36535   -71.82994 1.000 19.99097  ?  235 ILE B O   1 
ATOM   5673 C  CB  . ILE B 1 235 ? 45.43835  -2.93273  -72.12883 1.000 27.00491  ?  235 ILE B CB  1 
ATOM   5674 C  CG1 . ILE B 1 235 ? 44.23486  -3.86617  -72.03267 1.000 28.22582  ?  235 ILE B CG1 1 
ATOM   5675 C  CG2 . ILE B 1 235 ? 46.07780  -2.73240  -70.76083 1.000 19.44026  ?  235 ILE B CG2 1 
ATOM   5676 C  CD1 . ILE B 1 235 ? 44.60579  -5.26100  -71.59546 1.000 20.80690  ?  235 ILE B CD1 1 
ATOM   5677 N  N   . LEU B 1 236 ? 47.24002  -0.78837  -73.42980 1.000 23.71930  ?  236 LEU B N   1 
ATOM   5678 C  CA  . LEU B 1 236 ? 48.38868  0.11204   -73.38412 1.000 27.41751  ?  236 LEU B CA  1 
ATOM   5679 C  C   . LEU B 1 236 ? 47.98941  1.53807   -73.74938 1.000 26.00908  ?  236 LEU B C   1 
ATOM   5680 O  O   . LEU B 1 236 ? 48.39845  2.49687   -73.08125 1.000 24.42277  ?  236 LEU B O   1 
ATOM   5681 C  CB  . LEU B 1 236 ? 49.49236  -0.39422  -74.31243 1.000 25.26322  ?  236 LEU B CB  1 
ATOM   5682 C  CG  . LEU B 1 236 ? 50.19372  -1.68215  -73.87761 1.000 22.57832  ?  236 LEU B CG  1 
ATOM   5683 C  CD1 . LEU B 1 236 ? 51.29564  -2.05137  -74.85827 1.000 24.29001  ?  236 LEU B CD1 1 
ATOM   5684 C  CD2 . LEU B 1 236 ? 50.74961  -1.54028  -72.46818 1.000 18.10117  ?  236 LEU B CD2 1 
ATOM   5685 N  N   . GLU B 1 237 ? 47.17979  1.69526   -74.79973 1.000 24.89152  ?  237 GLU B N   1 
ATOM   5686 C  CA  . GLU B 1 237 ? 46.77287  3.02937   -75.23486 1.000 22.14803  ?  237 GLU B CA  1 
ATOM   5687 C  C   . GLU B 1 237 ? 45.94977  3.73776   -74.16473 1.000 20.42434  ?  237 GLU B C   1 
ATOM   5688 O  O   . GLU B 1 237 ? 46.17168  4.91880   -73.87444 1.000 22.85251  ?  237 GLU B O   1 
ATOM   5689 C  CB  . GLU B 1 237 ? 45.98465  2.93845   -76.54149 1.000 23.26181  ?  237 GLU B CB  1 
ATOM   5690 C  CG  . GLU B 1 237 ? 46.81331  2.52098   -77.74166 1.000 28.80874  ?  237 GLU B CG  1 
ATOM   5691 C  CD  . GLU B 1 237 ? 46.02741  2.57811   -79.03572 1.000 32.73630  ?  237 GLU B CD  1 
ATOM   5692 O  OE1 . GLU B 1 237 ? 44.78861  2.72933   -78.97496 1.000 29.95113  ?  237 GLU B OE1 1 
ATOM   5693 O  OE2 . GLU B 1 237 ? 46.64920  2.47659   -80.11376 1.000 38.29053  -1 237 GLU B OE2 1 
ATOM   5694 N  N   . GLU B 1 238 ? 44.99110  3.02880   -73.56546 1.000 25.04154  ?  238 GLU B N   1 
ATOM   5695 C  CA  . GLU B 1 238 ? 44.12285  3.64324   -72.56860 1.000 21.57932  ?  238 GLU B CA  1 
ATOM   5696 C  C   . GLU B 1 238 ? 44.89404  3.99523   -71.30586 1.000 24.17156  ?  238 GLU B C   1 
ATOM   5697 O  O   . GLU B 1 238 ? 44.62032  5.02260   -70.67384 1.000 21.63879  ?  238 GLU B O   1 
ATOM   5698 C  CB  . GLU B 1 238 ? 42.95273  2.71528   -72.24469 1.000 19.86559  ?  238 GLU B CB  1 
ATOM   5699 C  CG  . GLU B 1 238 ? 41.97353  2.53529   -73.39163 1.000 23.89591  ?  238 GLU B CG  1 
ATOM   5700 C  CD  . GLU B 1 238 ? 40.79525  1.65863   -73.01989 1.000 37.09195  ?  238 GLU B CD  1 
ATOM   5701 O  OE1 . GLU B 1 238 ? 40.68512  1.27914   -71.83432 1.000 43.35412  ?  238 GLU B OE1 1 
ATOM   5702 O  OE2 . GLU B 1 238 ? 39.97920  1.34897   -73.91371 1.000 36.93837  -1 238 GLU B OE2 1 
ATOM   5703 N  N   . PHE B 1 239 ? 45.85933  3.15785   -70.91534 1.000 26.26579  ?  239 PHE B N   1 
ATOM   5704 C  CA  . PHE B 1 239 ? 46.64238  3.48244   -69.72901 1.000 24.73593  ?  239 PHE B CA  1 
ATOM   5705 C  C   . PHE B 1 239 ? 47.61880  4.62228   -69.98858 1.000 22.98792  ?  239 PHE B C   1 
ATOM   5706 O  O   . PHE B 1 239 ? 47.88795  5.41710   -69.08096 1.000 22.76390  ?  239 PHE B O   1 
ATOM   5707 C  CB  . PHE B 1 239 ? 47.36962  2.24170   -69.21687 1.000 21.18642  ?  239 PHE B CB  1 
ATOM   5708 C  CG  . PHE B 1 239 ? 46.61782  1.51435   -68.14166 1.000 21.62290  ?  239 PHE B CG  1 
ATOM   5709 C  CD1 . PHE B 1 239 ? 45.60878  0.62273   -68.46485 1.000 25.83566  ?  239 PHE B CD1 1 
ATOM   5710 C  CD2 . PHE B 1 239 ? 46.90528  1.73916   -66.80584 1.000 21.68166  ?  239 PHE B CD2 1 
ATOM   5711 C  CE1 . PHE B 1 239 ? 44.90839  -0.04035  -67.47586 1.000 27.86968  ?  239 PHE B CE1 1 
ATOM   5712 C  CE2 . PHE B 1 239 ? 46.20865  1.08015   -65.81310 1.000 21.97223  ?  239 PHE B CE2 1 
ATOM   5713 C  CZ  . PHE B 1 239 ? 45.20839  0.18986   -66.14856 1.000 28.22502  ?  239 PHE B CZ  1 
ATOM   5714 N  N   . ARG B 1 240 ? 48.15806  4.72831   -71.20650 1.000 21.64580  ?  240 ARG B N   1 
ATOM   5715 C  CA  . ARG B 1 240 ? 48.97243  5.89605   -71.52806 1.000 24.59613  ?  240 ARG B CA  1 
ATOM   5716 C  C   . ARG B 1 240 ? 48.13106  7.16591   -71.54674 1.000 22.89737  ?  240 ARG B C   1 
ATOM   5717 O  O   . ARG B 1 240 ? 48.57436  8.21745   -71.07047 1.000 19.00175  ?  240 ARG B O   1 
ATOM   5718 C  CB  . ARG B 1 240 ? 49.67532  5.71616   -72.87144 1.000 23.72815  ?  240 ARG B CB  1 
ATOM   5719 C  CG  . ARG B 1 240 ? 50.52215  6.92293   -73.24496 1.000 23.33928  ?  240 ARG B CG  1 
ATOM   5720 C  CD  . ARG B 1 240 ? 50.83993  6.98286   -74.72464 1.000 29.18887  ?  240 ARG B CD  1 
ATOM   5721 N  NE  . ARG B 1 240 ? 51.51135  8.23251   -75.06128 1.000 32.20416  ?  240 ARG B NE  1 
ATOM   5722 C  CZ  . ARG B 1 240 ? 50.88700  9.34195   -75.43314 1.000 27.45342  ?  240 ARG B CZ  1 
ATOM   5723 N  NH1 . ARG B 1 240 ? 49.57003  9.38741   -75.55265 1.000 25.11929  ?  240 ARG B NH1 1 
ATOM   5724 N  NH2 . ARG B 1 240 ? 51.60210  10.43284  -75.69300 1.000 22.36866  ?  240 ARG B NH2 1 
ATOM   5725 N  N   . SER B 1 241 ? 46.91613  7.08786   -72.09869 1.000 26.99199  ?  241 SER B N   1 
ATOM   5726 C  CA  . SER B 1 241 ? 46.05947  8.26632   -72.18525 1.000 20.81539  ?  241 SER B CA  1 
ATOM   5727 C  C   . SER B 1 241 ? 45.69731  8.80168   -70.80724 1.000 23.19853  ?  241 SER B C   1 
ATOM   5728 O  O   . SER B 1 241 ? 45.49409  10.01025  -70.64546 1.000 25.03561  ?  241 SER B O   1 
ATOM   5729 C  CB  . SER B 1 241 ? 44.79389  7.93918   -72.97867 1.000 19.29206  ?  241 SER B CB  1 
ATOM   5730 O  OG  . SER B 1 241 ? 45.10587  7.58770   -74.31591 1.000 15.33725  ?  241 SER B OG  1 
ATOM   5731 N  N   . ASP B 1 242 ? 45.61169  7.92746   -69.80568 1.000 27.87064  ?  242 ASP B N   1 
ATOM   5732 C  CA  . ASP B 1 242 ? 45.36392  8.34507   -68.43448 1.000 25.94305  ?  242 ASP B CA  1 
ATOM   5733 C  C   . ASP B 1 242 ? 46.65160  8.65167   -67.67952 1.000 18.35645  ?  242 ASP B C   1 
ATOM   5734 O  O   . ASP B 1 242 ? 46.66327  8.59630   -66.44528 1.000 21.61468  ?  242 ASP B O   1 
ATOM   5735 C  CB  . ASP B 1 242 ? 44.55697  7.27926   -67.69130 1.000 36.07446  ?  242 ASP B CB  1 
ATOM   5736 C  CG  . ASP B 1 242 ? 43.70070  7.86742   -66.58872 1.000 31.93309  ?  242 ASP B CG  1 
ATOM   5737 O  OD1 . ASP B 1 242 ? 43.59008  9.10981   -66.53180 1.000 25.87486  ?  242 ASP B OD1 1 
ATOM   5738 O  OD2 . ASP B 1 242 ? 43.14171  7.09392   -65.78249 1.000 28.82950  -1 242 ASP B OD2 1 
ATOM   5739 N  N   . ASN B 1 243 ? 47.73372  8.95316   -68.39954 1.000 18.07984  ?  243 ASN B N   1 
ATOM   5740 C  CA  . ASN B 1 243 ? 49.00373  9.38696   -67.81518 1.000 19.51596  ?  243 ASN B CA  1 
ATOM   5741 C  C   . ASN B 1 243 ? 49.62904  8.32242   -66.91675 1.000 25.62957  ?  243 ASN B C   1 
ATOM   5742 O  O   . ASN B 1 243 ? 50.26943  8.64129   -65.91263 1.000 19.59788  ?  243 ASN B O   1 
ATOM   5743 C  CB  . ASN B 1 243 ? 48.83894  10.70444  -67.05305 1.000 18.65482  ?  243 ASN B CB  1 
ATOM   5744 C  CG  . ASN B 1 243 ? 48.48872  11.86049  -67.96731 1.000 23.71943  ?  243 ASN B CG  1 
ATOM   5745 O  OD1 . ASN B 1 243 ? 49.36871  12.48859  -68.55481 1.000 38.68278  ?  243 ASN B OD1 1 
ATOM   5746 N  ND2 . ASN B 1 243 ? 47.19823  12.14125  -68.10130 1.000 22.20989  ?  243 ASN B ND2 1 
ATOM   5747 N  N   . VAL B 1 244 ? 49.45855  7.05160   -67.26880 1.000 28.11455  ?  244 VAL B N   1 
ATOM   5748 C  CA  . VAL B 1 244 ? 50.18194  5.95232   -66.63911 1.000 21.28717  ?  244 VAL B CA  1 
ATOM   5749 C  C   . VAL B 1 244 ? 51.17875  5.42677   -67.66266 1.000 23.68079  ?  244 VAL B C   1 
ATOM   5750 O  O   . VAL B 1 244 ? 50.79021  5.00280   -68.75849 1.000 22.91080  ?  244 VAL B O   1 
ATOM   5751 C  CB  . VAL B 1 244 ? 49.23610  4.84325   -66.15433 1.000 18.12134  ?  244 VAL B CB  1 
ATOM   5752 C  CG1 . VAL B 1 244 ? 50.00406  3.80829   -65.34768 1.000 20.22572  ?  244 VAL B CG1 1 
ATOM   5753 C  CG2 . VAL B 1 244 ? 48.10611  5.43538   -65.32805 1.000 19.03255  ?  244 VAL B CG2 1 
ATOM   5754 N  N   . GLN B 1 245 ? 52.46281  5.45837   -67.30782 1.000 25.27243  ?  245 GLN B N   1 
ATOM   5755 C  CA  . GLN B 1 245 ? 53.54170  5.18295   -68.24692 1.000 27.79204  ?  245 GLN B CA  1 
ATOM   5756 C  C   . GLN B 1 245 ? 54.09881  3.76873   -68.13540 1.000 35.01823  ?  245 GLN B C   1 
ATOM   5757 O  O   . GLN B 1 245 ? 54.80068  3.31946   -69.04976 1.000 41.95847  ?  245 GLN B O   1 
ATOM   5758 C  CB  . GLN B 1 245 ? 54.67147  6.20073   -68.04316 1.000 30.00704  ?  245 GLN B CB  1 
ATOM   5759 C  CG  . GLN B 1 245 ? 54.19526  7.64855   -68.07661 1.000 35.67567  ?  245 GLN B CG  1 
ATOM   5760 C  CD  . GLN B 1 245 ? 55.00150  8.55827   -67.16684 1.000 36.16756  ?  245 GLN B CD  1 
ATOM   5761 O  OE1 . GLN B 1 245 ? 56.12255  8.95038   -67.49363 1.000 33.01889  ?  245 GLN B OE1 1 
ATOM   5762 N  NE2 . GLN B 1 245 ? 54.42951  8.90080   -66.01648 1.000 24.88432  ?  245 GLN B NE2 1 
ATOM   5763 N  N   . TYR B 1 246 ? 53.79881  3.05535   -67.05514 1.000 32.93969  ?  246 TYR B N   1 
ATOM   5764 C  CA  . TYR B 1 246 ? 54.33443  1.72190   -66.83398 1.000 30.31369  ?  246 TYR B CA  1 
ATOM   5765 C  C   . TYR B 1 246 ? 53.22144  0.82113   -66.32226 1.000 32.64712  ?  246 TYR B C   1 
ATOM   5766 O  O   . TYR B 1 246 ? 52.36611  1.26199   -65.55170 1.000 25.72618  ?  246 TYR B O   1 
ATOM   5767 C  CB  . TYR B 1 246 ? 55.50251  1.76997   -65.84250 1.000 26.83265  ?  246 TYR B CB  1 
ATOM   5768 C  CG  . TYR B 1 246 ? 56.13196  0.43387   -65.54050 1.000 29.30500  ?  246 TYR B CG  1 
ATOM   5769 C  CD1 . TYR B 1 246 ? 56.97645  -0.18156  -66.45479 1.000 30.21290  ?  246 TYR B CD1 1 
ATOM   5770 C  CD2 . TYR B 1 246 ? 55.89856  -0.20326  -64.32984 1.000 29.14097  ?  246 TYR B CD2 1 
ATOM   5771 C  CE1 . TYR B 1 246 ? 57.56039  -1.40280  -66.17535 1.000 35.53635  ?  246 TYR B CE1 1 
ATOM   5772 C  CE2 . TYR B 1 246 ? 56.47795  -1.42058  -64.04080 1.000 28.53869  ?  246 TYR B CE2 1 
ATOM   5773 C  CZ  . TYR B 1 246 ? 57.30699  -2.01767  -64.96617 1.000 31.04571  ?  246 TYR B CZ  1 
ATOM   5774 O  OH  . TYR B 1 246 ? 57.88474  -3.23304  -64.67936 1.000 25.15151  ?  246 TYR B OH  1 
ATOM   5775 N  N   . VAL B 1 247 ? 53.21317  -0.43167  -66.77543 1.000 37.82959  ?  247 VAL B N   1 
ATOM   5776 C  CA  . VAL B 1 247 ? 52.20752  -1.39312  -66.33191 1.000 26.42464  ?  247 VAL B CA  1 
ATOM   5777 C  C   . VAL B 1 247 ? 52.84345  -2.76291  -66.13359 1.000 27.35050  ?  247 VAL B C   1 
ATOM   5778 O  O   . VAL B 1 247 ? 53.79009  -3.14084  -66.83046 1.000 29.96865  ?  247 VAL B O   1 
ATOM   5779 C  CB  . VAL B 1 247 ? 51.01136  -1.49689  -67.31075 1.000 17.03415  ?  247 VAL B CB  1 
ATOM   5780 C  CG1 . VAL B 1 247 ? 50.13572  -0.25300  -67.23507 1.000 23.56266  ?  247 VAL B CG1 1 
ATOM   5781 C  CG2 . VAL B 1 247 ? 51.49311  -1.71803  -68.72598 1.000 15.28759  ?  247 VAL B CG2 1 
ATOM   5782 N  N   . GLU B 1 248 ? 52.31236  -3.50608  -65.16205 1.000 24.80946  ?  248 GLU B N   1 
ATOM   5783 C  CA  . GLU B 1 248 ? 52.67678  -4.90376  -64.92747 1.000 22.79118  ?  248 GLU B CA  1 
ATOM   5784 C  C   . GLU B 1 248 ? 51.38151  -5.70985  -64.92097 1.000 22.83798  ?  248 GLU B C   1 
ATOM   5785 O  O   . GLU B 1 248 ? 50.62542  -5.68400  -63.94490 1.000 21.33121  ?  248 GLU B O   1 
ATOM   5786 C  CB  . GLU B 1 248 ? 53.45439  -5.07258  -63.62737 1.000 27.17265  ?  248 GLU B CB  1 
ATOM   5787 C  CG  . GLU B 1 248 ? 54.84450  -4.46575  -63.66955 1.000 25.17047  ?  248 GLU B CG  1 
ATOM   5788 C  CD  . GLU B 1 248 ? 55.66821  -4.80160  -62.44339 1.000 25.80987  ?  248 GLU B CD  1 
ATOM   5789 O  OE1 . GLU B 1 248 ? 55.25515  -5.69150  -61.67146 1.000 20.87298  ?  248 GLU B OE1 1 
ATOM   5790 O  OE2 . GLU B 1 248 ? 56.73128  -4.17558  -62.25241 1.000 35.53648  -1 248 GLU B OE2 1 
ATOM   5791 N  N   . VAL B 1 249 ? 51.14294  -6.43394  -66.00913 1.000 24.53674  ?  249 VAL B N   1 
ATOM   5792 C  CA  . VAL B 1 249 ? 49.85239  -7.05213  -66.28879 1.000 22.53416  ?  249 VAL B CA  1 
ATOM   5793 C  C   . VAL B 1 249 ? 49.94314  -8.54914  -66.03381 1.000 25.75757  ?  249 VAL B C   1 
ATOM   5794 O  O   . VAL B 1 249 ? 50.87755  -9.21301  -66.49857 1.000 23.44611  ?  249 VAL B O   1 
ATOM   5795 C  CB  . VAL B 1 249 ? 49.40823  -6.77000  -67.73371 1.000 15.88112  ?  249 VAL B CB  1 
ATOM   5796 C  CG1 . VAL B 1 249 ? 47.99806  -7.27435  -67.95912 1.000 19.47280  ?  249 VAL B CG1 1 
ATOM   5797 C  CG2 . VAL B 1 249 ? 49.50380  -5.28381  -68.03513 1.000 19.86280  ?  249 VAL B CG2 1 
ATOM   5798 N  N   . ARG B 1 250 ? 48.97695  -9.07901  -65.28899 1.000 28.92640  ?  250 ARG B N   1 
ATOM   5799 C  CA  . ARG B 1 250 ? 48.85643  -10.51368 -65.07410 1.000 21.94759  ?  250 ARG B CA  1 
ATOM   5800 C  C   . ARG B 1 250 ? 48.02134  -11.12120 -66.19298 1.000 23.13199  ?  250 ARG B C   1 
ATOM   5801 O  O   . ARG B 1 250 ? 46.95687  -10.59808 -66.53637 1.000 29.68877  ?  250 ARG B O   1 
ATOM   5802 C  CB  . ARG B 1 250 ? 48.22536  -10.80651 -63.71297 1.000 16.92226  ?  250 ARG B CB  1 
ATOM   5803 C  CG  . ARG B 1 250 ? 49.14518  -10.51810 -62.54020 1.000 23.15323  ?  250 ARG B CG  1 
ATOM   5804 C  CD  . ARG B 1 250 ? 48.39052  -10.53140 -61.22368 1.000 20.85685  ?  250 ARG B CD  1 
ATOM   5805 N  NE  . ARG B 1 250 ? 49.28170  -10.35111 -60.08412 1.000 17.56092  ?  250 ARG B NE  1 
ATOM   5806 C  CZ  . ARG B 1 250 ? 49.75112  -9.17983  -59.67671 1.000 20.99598  ?  250 ARG B CZ  1 
ATOM   5807 N  NH1 . ARG B 1 250 ? 49.45051  -8.05651  -60.30773 1.000 24.04342  ?  250 ARG B NH1 1 
ATOM   5808 N  NH2 . ARG B 1 250 ? 50.54445  -9.13448  -58.61062 1.000 25.15035  ?  250 ARG B NH2 1 
ATOM   5809 N  N   . SER B 1 251 ? 48.50873  -12.22216 -66.75861 1.000 24.55600  ?  251 SER B N   1 
ATOM   5810 C  CA  . SER B 1 251 ? 47.87391  -12.84354 -67.91006 1.000 24.54903  ?  251 SER B CA  1 
ATOM   5811 C  C   . SER B 1 251 ? 48.05945  -14.35163 -67.83100 1.000 23.66803  ?  251 SER B C   1 
ATOM   5812 O  O   . SER B 1 251 ? 49.01497  -14.84144 -67.22472 1.000 20.62361  ?  251 SER B O   1 
ATOM   5813 C  CB  . SER B 1 251 ? 48.45832  -12.29886 -69.22019 1.000 20.33555  ?  251 SER B CB  1 
ATOM   5814 O  OG  . SER B 1 251 ? 47.95652  -13.00201 -70.34205 1.000 26.81734  ?  251 SER B OG  1 
ATOM   5815 N  N   . SER B 1 252 ? 47.11542  -15.08651 -68.42277 1.000 18.77817  ?  252 SER B N   1 
ATOM   5816 C  CA  . SER B 1 252 ? 47.28594  -16.52817 -68.56101 1.000 19.75091  ?  252 SER B CA  1 
ATOM   5817 C  C   . SER B 1 252 ? 48.20893  -16.87166 -69.72348 1.000 28.00023  ?  252 SER B C   1 
ATOM   5818 O  O   . SER B 1 252 ? 48.85352  -17.92689 -69.70601 1.000 37.38611  ?  252 SER B O   1 
ATOM   5819 C  CB  . SER B 1 252 ? 45.92742  -17.20922 -68.73264 1.000 22.87560  ?  252 SER B CB  1 
ATOM   5820 O  OG  . SER B 1 252 ? 45.21535  -16.66404 -69.82793 1.000 31.84780  ?  252 SER B OG  1 
ATOM   5821 N  N   . LEU B 1 253 ? 48.24399  -16.01496 -70.74845 1.000 24.74248  ?  253 LEU B N   1 
ATOM   5822 C  CA  . LEU B 1 253 ? 49.23628  -16.02797 -71.82152 1.000 24.15690  ?  253 LEU B CA  1 
ATOM   5823 C  C   . LEU B 1 253 ? 49.05711  -17.18040 -72.80226 1.000 29.77581  ?  253 LEU B C   1 
ATOM   5824 O  O   . LEU B 1 253 ? 49.69739  -17.19804 -73.85827 1.000 34.10339  ?  253 LEU B O   1 
ATOM   5825 C  CB  . LEU B 1 253 ? 50.65388  -16.07168 -71.24087 1.000 20.10779  ?  253 LEU B CB  1 
ATOM   5826 C  CG  . LEU B 1 253 ? 51.16239  -14.81558 -70.53668 1.000 23.41380  ?  253 LEU B CG  1 
ATOM   5827 C  CD1 . LEU B 1 253 ? 52.52885  -15.07042 -69.92255 1.000 23.40451  ?  253 LEU B CD1 1 
ATOM   5828 C  CD2 . LEU B 1 253 ? 51.21974  -13.65508 -71.51504 1.000 28.15354  ?  253 LEU B CD2 1 
ATOM   5829 N  N   . SER B 1 254 ? 48.16857  -18.12027 -72.49663 1.000 28.55764  ?  254 SER B N   1 
ATOM   5830 C  CA  . SER B 1 254 ? 48.01466  -19.31980 -73.30286 1.000 27.94994  ?  254 SER B CA  1 
ATOM   5831 C  C   . SER B 1 254 ? 46.55630  -19.49015 -73.69883 1.000 27.35006  ?  254 SER B C   1 
ATOM   5832 O  O   . SER B 1 254 ? 45.64556  -18.97983 -73.04148 1.000 28.05888  ?  254 SER B O   1 
ATOM   5833 C  CB  . SER B 1 254 ? 48.50861  -20.56873 -72.55824 1.000 25.68845  ?  254 SER B CB  1 
ATOM   5834 O  OG  . SER B 1 254 ? 47.75892  -20.79045 -71.37655 1.000 39.49111  ?  254 SER B OG  1 
ATOM   5835 N  N   . GLY B 1 255 ? 46.34813  -20.21959 -74.78935 1.000 21.17957  ?  255 GLY B N   1 
ATOM   5836 C  CA  . GLY B 1 255 ? 45.02100  -20.46845 -75.30266 1.000 22.00816  ?  255 GLY B CA  1 
ATOM   5837 C  C   . GLY B 1 255 ? 44.55954  -19.53101 -76.39325 1.000 25.71411  ?  255 GLY B C   1 
ATOM   5838 O  O   . GLY B 1 255 ? 43.39571  -19.61668 -76.80207 1.000 21.95876  ?  255 GLY B O   1 
ATOM   5839 N  N   . PHE B 1 256 ? 45.42327  -18.63693 -76.87211 1.000 35.02337  ?  256 PHE B N   1 
ATOM   5840 C  CA  . PHE B 1 256 ? 45.04617  -17.76082 -77.97352 1.000 32.75593  ?  256 PHE B CA  1 
ATOM   5841 C  C   . PHE B 1 256 ? 44.80602  -18.59854 -79.22081 1.000 32.52390  ?  256 PHE B C   1 
ATOM   5842 O  O   . PHE B 1 256 ? 45.67358  -19.37062 -79.63912 1.000 31.91837  ?  256 PHE B O   1 
ATOM   5843 C  CB  . PHE B 1 256 ? 46.13563  -16.71826 -78.24145 1.000 27.26261  ?  256 PHE B CB  1 
ATOM   5844 C  CG  . PHE B 1 256 ? 46.40932  -15.79341 -77.08252 1.000 32.69638  ?  256 PHE B CG  1 
ATOM   5845 C  CD1 . PHE B 1 256 ? 45.62545  -15.82101 -75.93940 1.000 30.73709  ?  256 PHE B CD1 1 
ATOM   5846 C  CD2 . PHE B 1 256 ? 47.45302  -14.88441 -77.14699 1.000 34.62260  ?  256 PHE B CD2 1 
ATOM   5847 C  CE1 . PHE B 1 256 ? 45.88615  -14.97339 -74.88290 1.000 31.64988  ?  256 PHE B CE1 1 
ATOM   5848 C  CE2 . PHE B 1 256 ? 47.71386  -14.02906 -76.09398 1.000 28.59466  ?  256 PHE B CE2 1 
ATOM   5849 C  CZ  . PHE B 1 256 ? 46.93165  -14.07548 -74.96044 1.000 32.66649  ?  256 PHE B CZ  1 
ATOM   5850 N  N   . PHE B 1 257 ? 43.62542  -18.45330 -79.81374 1.000 25.19968  ?  257 PHE B N   1 
ATOM   5851 C  CA  . PHE B 1 257 ? 43.22845  -19.30522 -80.92131 1.000 24.13960  ?  257 PHE B CA  1 
ATOM   5852 C  C   . PHE B 1 257 ? 42.97776  -18.48105 -82.17576 1.000 26.24741  ?  257 PHE B C   1 
ATOM   5853 O  O   . PHE B 1 257 ? 42.77507  -17.26612 -82.12092 1.000 30.48057  ?  257 PHE B O   1 
ATOM   5854 C  CB  . PHE B 1 257 ? 41.98243  -20.13561 -80.57588 1.000 22.85002  ?  257 PHE B CB  1 
ATOM   5855 C  CG  . PHE B 1 257 ? 40.73463  -19.32196 -80.38863 1.000 16.77948  ?  257 PHE B CG  1 
ATOM   5856 C  CD1 . PHE B 1 257 ? 40.43307  -18.76424 -79.15794 1.000 16.51038  ?  257 PHE B CD1 1 
ATOM   5857 C  CD2 . PHE B 1 257 ? 39.85140  -19.13375 -81.43850 1.000 16.44462  ?  257 PHE B CD2 1 
ATOM   5858 C  CE1 . PHE B 1 257 ? 39.28113  -18.02277 -78.98220 1.000 18.15313  ?  257 PHE B CE1 1 
ATOM   5859 C  CE2 . PHE B 1 257 ? 38.69958  -18.39271 -81.26895 1.000 19.94440  ?  257 PHE B CE2 1 
ATOM   5860 C  CZ  . PHE B 1 257 ? 38.41339  -17.83707 -80.03944 1.000 18.52270  ?  257 PHE B CZ  1 
ATOM   5861 N  N   . GLU B 1 258 ? 43.00492  -19.16743 -83.31284 1.000 27.21306  ?  258 GLU B N   1 
ATOM   5862 C  CA  . GLU B 1 258 ? 42.75524  -18.58317 -84.62072 1.000 27.16160  ?  258 GLU B CA  1 
ATOM   5863 C  C   . GLU B 1 258 ? 41.42068  -19.09256 -85.15790 1.000 31.77190  ?  258 GLU B C   1 
ATOM   5864 O  O   . GLU B 1 258 ? 40.72370  -19.88297 -84.51447 1.000 31.96613  ?  258 GLU B O   1 
ATOM   5865 C  CB  . GLU B 1 258 ? 43.89927  -18.91228 -85.58295 1.000 25.20633  ?  258 GLU B CB  1 
ATOM   5866 C  CG  . GLU B 1 258 ? 45.29020  -18.72064 -84.99688 1.000 24.39219  ?  258 GLU B CG  1 
ATOM   5867 C  CD  . GLU B 1 258 ? 45.65945  -17.26193 -84.81137 1.000 33.48379  ?  258 GLU B CD  1 
ATOM   5868 O  OE1 . GLU B 1 258 ? 44.95372  -16.38820 -85.35986 1.000 38.57962  ?  258 GLU B OE1 1 
ATOM   5869 O  OE2 . GLU B 1 258 ? 46.66085  -16.98905 -84.11580 1.000 33.23338  -1 258 GLU B OE2 1 
ATOM   5870 N  N   . LEU B 1 259 ? 41.06450  -18.62760 -86.35820 1.000 28.54410  ?  259 LEU B N   1 
ATOM   5871 C  CA  . LEU B 1 259 ? 39.81426  -19.06416 -86.97143 1.000 26.89372  ?  259 LEU B CA  1 
ATOM   5872 C  C   . LEU B 1 259 ? 39.85327  -20.53927 -87.34992 1.000 25.94024  ?  259 LEU B C   1 
ATOM   5873 O  O   . LEU B 1 259 ? 38.80985  -21.20229 -87.35562 1.000 27.21404  ?  259 LEU B O   1 
ATOM   5874 C  CB  . LEU B 1 259 ? 39.49919  -18.20973 -88.19908 1.000 21.00353  ?  259 LEU B CB  1 
ATOM   5875 C  CG  . LEU B 1 259 ? 39.08865  -16.76302 -87.92259 1.000 21.14256  ?  259 LEU B CG  1 
ATOM   5876 C  CD1 . LEU B 1 259 ? 38.65436  -16.07186 -89.20453 1.000 32.40533  ?  259 LEU B CD1 1 
ATOM   5877 C  CD2 . LEU B 1 259 ? 37.98083  -16.71436 -86.88576 1.000 23.51145  ?  259 LEU B CD2 1 
ATOM   5878 N  N   . ASP B 1 260 ? 41.03548  -21.07109 -87.66236 1.000 22.27238  ?  260 ASP B N   1 
ATOM   5879 C  CA  . ASP B 1 260 ? 41.15775  -22.47262 -88.04280 1.000 23.59905  ?  260 ASP B CA  1 
ATOM   5880 C  C   . ASP B 1 260 ? 41.11702  -23.42033 -86.85103 1.000 29.07001  ?  260 ASP B C   1 
ATOM   5881 O  O   . ASP B 1 260 ? 41.08768  -24.63927 -87.05235 1.000 37.14949  ?  260 ASP B O   1 
ATOM   5882 C  CB  . ASP B 1 260 ? 42.44824  -22.69739 -88.84314 1.000 23.61208  ?  260 ASP B CB  1 
ATOM   5883 C  CG  . ASP B 1 260 ? 43.69874  -22.24251 -88.10103 1.000 30.36335  ?  260 ASP B CG  1 
ATOM   5884 O  OD1 . ASP B 1 260 ? 43.61566  -21.91540 -86.89892 1.000 36.01158  ?  260 ASP B OD1 1 
ATOM   5885 O  OD2 . ASP B 1 260 ? 44.77723  -22.21016 -88.73092 1.000 30.93939  -1 260 ASP B OD2 1 
ATOM   5886 N  N   . GLY B 1 261 ? 41.11269  -22.89758 -85.62638 1.000 26.73080  ?  261 GLY B N   1 
ATOM   5887 C  CA  . GLY B 1 261 ? 41.09225  -23.71815 -84.43507 1.000 26.02219  ?  261 GLY B CA  1 
ATOM   5888 C  C   . GLY B 1 261 ? 42.43764  -23.93081 -83.77857 1.000 33.82404  ?  261 GLY B C   1 
ATOM   5889 O  O   . GLY B 1 261 ? 42.49604  -24.58202 -82.72757 1.000 31.08498  ?  261 GLY B O   1 
ATOM   5890 N  N   . THR B 1 262 ? 43.51669  -23.41315 -84.36387 1.000 33.94946  ?  262 THR B N   1 
ATOM   5891 C  CA  . THR B 1 262 ? 44.83870  -23.55181 -83.76635 1.000 35.81181  ?  262 THR B CA  1 
ATOM   5892 C  C   . THR B 1 262 ? 44.87522  -22.87361 -82.40487 1.000 31.96021  ?  262 THR B C   1 
ATOM   5893 O  O   . THR B 1 262 ? 44.42961  -21.73470 -82.25727 1.000 32.94447  ?  262 THR B O   1 
ATOM   5894 C  CB  . THR B 1 262 ? 45.89789  -22.93897 -84.68410 1.000 25.72657  ?  262 THR B CB  1 
ATOM   5895 O  OG1 . THR B 1 262 ? 45.87795  -23.60196 -85.95501 1.000 31.08705  ?  262 THR B OG1 1 
ATOM   5896 C  CG2 . THR B 1 262 ? 47.28399  -23.06745 -84.06482 1.000 23.25549  ?  262 THR B CG2 1 
ATOM   5897 N  N   . VAL B 1 263 ? 45.41154  -23.57411 -81.40883 1.000 32.63891  ?  263 VAL B N   1 
ATOM   5898 C  CA  . VAL B 1 263 ? 45.54040  -23.05509 -80.05184 1.000 30.99739  ?  263 VAL B CA  1 
ATOM   5899 C  C   . VAL B 1 263 ? 47.02178  -22.96140 -79.71939 1.000 38.08267  ?  263 VAL B C   1 
ATOM   5900 O  O   . VAL B 1 263 ? 47.75066  -23.95382 -79.82713 1.000 55.33514  ?  263 VAL B O   1 
ATOM   5901 C  CB  . VAL B 1 263 ? 44.80074  -23.93717 -79.03060 1.000 28.11732  ?  263 VAL B CB  1 
ATOM   5902 C  CG1 . VAL B 1 263 ? 45.05869  -23.44026 -77.61641 1.000 31.00601  ?  263 VAL B CG1 1 
ATOM   5903 C  CG2 . VAL B 1 263 ? 43.30893  -23.95140 -79.33025 1.000 27.10045  ?  263 VAL B CG2 1 
ATOM   5904 N  N   . HIS B 1 264 ? 47.46187  -21.77397 -79.31934 1.000 32.49879  ?  264 HIS B N   1 
ATOM   5905 C  CA  . HIS B 1 264 ? 48.86968  -21.50067 -79.07954 1.000 35.67426  ?  264 HIS B CA  1 
ATOM   5906 C  C   . HIS B 1 264 ? 49.21246  -21.63552 -77.60011 1.000 31.91498  ?  264 HIS B C   1 
ATOM   5907 O  O   . HIS B 1 264 ? 48.34676  -21.56963 -76.72388 1.000 32.43584  ?  264 HIS B O   1 
ATOM   5908 C  CB  . HIS B 1 264 ? 49.23784  -20.09847 -79.56733 1.000 40.71988  ?  264 HIS B CB  1 
ATOM   5909 C  CG  . HIS B 1 264 ? 48.90272  -19.84663 -81.00464 1.000 39.45985  ?  264 HIS B CG  1 
ATOM   5910 N  ND1 . HIS B 1 264 ? 49.56634  -20.46267 -82.04368 1.000 36.57194  ?  264 HIS B ND1 1 
ATOM   5911 C  CD2 . HIS B 1 264 ? 47.98171  -19.03459 -81.57575 1.000 32.53514  ?  264 HIS B CD2 1 
ATOM   5912 C  CE1 . HIS B 1 264 ? 49.06374  -20.04632 -83.19249 1.000 39.83636  ?  264 HIS B CE1 1 
ATOM   5913 N  NE2 . HIS B 1 264 ? 48.10150  -19.17846 -82.93645 1.000 30.16371  ?  264 HIS B NE2 1 
ATOM   5914 N  N   . ASP B 1 265 ? 50.50474  -21.81466 -77.33474 1.000 29.63118  ?  265 ASP B N   1 
ATOM   5915 C  CA  . ASP B 1 265 ? 51.01385  -21.96340 -75.98222 1.000 26.95862  ?  265 ASP B CA  1 
ATOM   5916 C  C   . ASP B 1 265 ? 51.26194  -20.59195 -75.35580 1.000 27.58297  ?  265 ASP B C   1 
ATOM   5917 O  O   . ASP B 1 265 ? 51.07714  -19.54667 -75.98420 1.000 28.73618  ?  265 ASP B O   1 
ATOM   5918 C  CB  . ASP B 1 265 ? 52.28678  -22.81225 -75.97824 1.000 29.58361  ?  265 ASP B CB  1 
ATOM   5919 C  CG  . ASP B 1 265 ? 53.43047  -22.16748 -76.74857 1.000 35.04540  ?  265 ASP B CG  1 
ATOM   5920 O  OD1 . ASP B 1 265 ? 53.22051  -21.74095 -77.90421 1.000 33.73086  ?  265 ASP B OD1 1 
ATOM   5921 O  OD2 . ASP B 1 265 ? 54.54709  -22.08720 -76.19397 1.000 30.37382  -1 265 ASP B OD2 1 
ATOM   5922 N  N   . ALA B 1 266 ? 51.68800  -20.59994 -74.08929 1.000 28.22831  ?  266 ALA B N   1 
ATOM   5923 C  CA  . ALA B 1 266 ? 51.92481  -19.35042 -73.37341 1.000 26.85661  ?  266 ALA B CA  1 
ATOM   5924 C  C   . ALA B 1 266 ? 53.05036  -18.54036 -74.00262 1.000 28.84902  ?  266 ALA B C   1 
ATOM   5925 O  O   . ALA B 1 266 ? 53.03388  -17.30445 -73.94413 1.000 32.43572  ?  266 ALA B O   1 
ATOM   5926 C  CB  . ALA B 1 266 ? 52.23440  -19.63804 -71.90442 1.000 25.39290  ?  266 ALA B CB  1 
ATOM   5927 N  N   . GLU B 1 267 ? 54.03366  -19.21299 -74.60381 1.000 28.14942  ?  267 GLU B N   1 
ATOM   5928 C  CA  . GLU B 1 267 ? 55.15022  -18.49994 -75.21447 1.000 30.51503  ?  267 GLU B CA  1 
ATOM   5929 C  C   . GLU B 1 267 ? 54.68565  -17.64744 -76.38923 1.000 24.81079  ?  267 GLU B C   1 
ATOM   5930 O  O   . GLU B 1 267 ? 55.16815  -16.52504 -76.57889 1.000 29.20242  ?  267 GLU B O   1 
ATOM   5931 C  CB  . GLU B 1 267 ? 56.22505  -19.49313 -75.65441 1.000 34.71909  ?  267 GLU B CB  1 
ATOM   5932 C  CG  . GLU B 1 267 ? 57.55701  -18.85389 -76.00298 1.000 31.40704  ?  267 GLU B CG  1 
ATOM   5933 C  CD  . GLU B 1 267 ? 58.64811  -19.88023 -76.23569 1.000 45.53696  ?  267 GLU B CD  1 
ATOM   5934 O  OE1 . GLU B 1 267 ? 58.33308  -21.08867 -76.26806 1.000 50.92880  ?  267 GLU B OE1 1 
ATOM   5935 O  OE2 . GLU B 1 267 ? 59.82143  -19.47941 -76.38220 1.000 46.15942  -1 267 GLU B OE2 1 
ATOM   5936 N  N   . PHE B 1 268 ? 53.74584  -18.16116 -77.18680 1.000 22.59309  ?  268 PHE B N   1 
ATOM   5937 C  CA  . PHE B 1 268 ? 53.23047  -17.39441 -78.31771 1.000 25.82758  ?  268 PHE B CA  1 
ATOM   5938 C  C   . PHE B 1 268 ? 52.54852  -16.11526 -77.85012 1.000 31.51560  ?  268 PHE B C   1 
ATOM   5939 O  O   . PHE B 1 268 ? 52.80230  -15.02994 -78.38611 1.000 35.95391  ?  268 PHE B O   1 
ATOM   5940 C  CB  . PHE B 1 268 ? 52.25952  -18.25007 -79.13239 1.000 26.14786  ?  268 PHE B CB  1 
ATOM   5941 C  CG  . PHE B 1 268 ? 51.52181  -17.48591 -80.20032 1.000 27.36150  ?  268 PHE B CG  1 
ATOM   5942 C  CD1 . PHE B 1 268 ? 52.05247  -17.36377 -81.47328 1.000 37.63575  ?  268 PHE B CD1 1 
ATOM   5943 C  CD2 . PHE B 1 268 ? 50.29560  -16.89418 -79.93293 1.000 25.56433  ?  268 PHE B CD2 1 
ATOM   5944 C  CE1 . PHE B 1 268 ? 51.37754  -16.66485 -82.45714 1.000 34.87785  ?  268 PHE B CE1 1 
ATOM   5945 C  CE2 . PHE B 1 268 ? 49.61828  -16.19411 -80.91123 1.000 29.47773  ?  268 PHE B CE2 1 
ATOM   5946 C  CZ  . PHE B 1 268 ? 50.15898  -16.08032 -82.17522 1.000 31.23395  ?  268 PHE B CZ  1 
ATOM   5947 N  N   . GLY B 1 269 ? 51.66317  -16.22798 -76.85840 1.000 31.36726  ?  269 GLY B N   1 
ATOM   5948 C  CA  . GLY B 1 269 ? 50.98492  -15.04698 -76.35176 1.000 28.97491  ?  269 GLY B CA  1 
ATOM   5949 C  C   . GLY B 1 269 ? 51.93952  -14.06439 -75.70387 1.000 29.53223  ?  269 GLY B C   1 
ATOM   5950 O  O   . GLY B 1 269 ? 51.79065  -12.84731 -75.85014 1.000 27.51336  ?  269 GLY B O   1 
ATOM   5951 N  N   . LEU B 1 270 ? 52.93581  -14.57934 -74.97976 1.000 27.85420  ?  270 LEU B N   1 
ATOM   5952 C  CA  . LEU B 1 270 ? 53.93643  -13.70578 -74.37938 1.000 30.28727  ?  270 LEU B CA  1 
ATOM   5953 C  C   . LEU B 1 270 ? 54.71388  -12.94739 -75.44788 1.000 31.16120  ?  270 LEU B C   1 
ATOM   5954 O  O   . LEU B 1 270 ? 54.96475  -11.74570 -75.30707 1.000 35.71446  ?  270 LEU B O   1 
ATOM   5955 C  CB  . LEU B 1 270 ? 54.88270  -14.52239 -73.50015 1.000 28.82969  ?  270 LEU B CB  1 
ATOM   5956 C  CG  . LEU B 1 270 ? 55.86997  -13.72653 -72.64588 1.000 27.93194  ?  270 LEU B CG  1 
ATOM   5957 C  CD1 . LEU B 1 270 ? 55.12989  -12.89534 -71.60718 1.000 22.19468  ?  270 LEU B CD1 1 
ATOM   5958 C  CD2 . LEU B 1 270 ? 56.87406  -14.65541 -71.98321 1.000 29.82744  ?  270 LEU B CD2 1 
ATOM   5959 N  N   . ASN B 1 271 ? 55.09552  -13.62996 -76.53030 1.000 26.05800  ?  271 ASN B N   1 
ATOM   5960 C  CA  . ASN B 1 271 ? 55.81667  -12.96163 -77.60906 1.000 26.92314  ?  271 ASN B CA  1 
ATOM   5961 C  C   . ASN B 1 271 ? 54.93233  -11.94971 -78.32554 1.000 27.81925  ?  271 ASN B C   1 
ATOM   5962 O  O   . ASN B 1 271 ? 55.41280  -10.89741 -78.76093 1.000 31.69455  ?  271 ASN B O   1 
ATOM   5963 C  CB  . ASN B 1 271 ? 56.36419  -13.99391 -78.59251 1.000 24.85291  ?  271 ASN B CB  1 
ATOM   5964 C  CG  . ASN B 1 271 ? 57.72268  -14.52289 -78.18020 1.000 31.92380  ?  271 ASN B CG  1 
ATOM   5965 O  OD1 . ASN B 1 271 ? 58.64538  -13.75229 -77.91156 1.000 34.69816  ?  271 ASN B OD1 1 
ATOM   5966 N  ND2 . ASN B 1 271 ? 57.85081  -15.84291 -78.11819 1.000 34.16230  ?  271 ASN B ND2 1 
ATOM   5967 N  N   . LEU B 1 272 ? 53.64126  -12.25396 -78.46692 1.000 28.42298  ?  272 LEU B N   1 
ATOM   5968 C  CA  . LEU B 1 272 ? 52.71339  -11.29381 -79.05722 1.000 29.07591  ?  272 LEU B CA  1 
ATOM   5969 C  C   . LEU B 1 272 ? 52.62639  -10.03225 -78.20455 1.000 27.09341  ?  272 LEU B C   1 
ATOM   5970 O  O   . LEU B 1 272 ? 52.70034  -8.90599  -78.71990 1.000 25.53637  ?  272 LEU B O   1 
ATOM   5971 C  CB  . LEU B 1 272 ? 51.33932  -11.94759 -79.22348 1.000 19.37804  ?  272 LEU B CB  1 
ATOM   5972 C  CG  . LEU B 1 272 ? 50.19320  -11.16811 -79.86761 1.000 20.80421  ?  272 LEU B CG  1 
ATOM   5973 C  CD1 . LEU B 1 272 ? 49.29434  -12.11815 -80.63820 1.000 24.33041  ?  272 LEU B CD1 1 
ATOM   5974 C  CD2 . LEU B 1 272 ? 49.38857  -10.43021 -78.81192 1.000 28.26444  ?  272 LEU B CD2 1 
ATOM   5975 N  N   . TYR B 1 273 ? 52.48421  -10.20852 -76.88727 1.000 24.25450  ?  273 TYR B N   1 
ATOM   5976 C  CA  . TYR B 1 273 ? 52.48449  -9.06717  -75.97783 1.000 24.88480  ?  273 TYR B CA  1 
ATOM   5977 C  C   . TYR B 1 273 ? 53.78651  -8.28550  -76.08320 1.000 24.29106  ?  273 TYR B C   1 
ATOM   5978 O  O   . TYR B 1 273 ? 53.77883  -7.05041  -76.08815 1.000 24.38364  ?  273 TYR B O   1 
ATOM   5979 C  CB  . TYR B 1 273 ? 52.27152  -9.53360  -74.53581 1.000 29.80942  ?  273 TYR B CB  1 
ATOM   5980 C  CG  . TYR B 1 273 ? 50.83272  -9.79701  -74.14143 1.000 24.53215  ?  273 TYR B CG  1 
ATOM   5981 C  CD1 . TYR B 1 273 ? 49.80832  -9.75896  -75.07828 1.000 18.36133  ?  273 TYR B CD1 1 
ATOM   5982 C  CD2 . TYR B 1 273 ? 50.50058  -10.06946 -72.82003 1.000 20.58994  ?  273 TYR B CD2 1 
ATOM   5983 C  CE1 . TYR B 1 273 ? 48.49522  -9.99683  -74.70954 1.000 16.57886  ?  273 TYR B CE1 1 
ATOM   5984 C  CE2 . TYR B 1 273 ? 49.19352  -10.30652 -72.44304 1.000 19.06205  ?  273 TYR B CE2 1 
ATOM   5985 C  CZ  . TYR B 1 273 ? 48.19472  -10.26889 -73.38983 1.000 18.70015  ?  273 TYR B CZ  1 
ATOM   5986 O  OH  . TYR B 1 273 ? 46.89190  -10.50495 -73.01243 1.000 18.23561  ?  273 TYR B OH  1 
ATOM   5987 N  N   . LYS B 1 274 ? 54.91591  -8.99384  -76.15925 1.000 31.75474  ?  274 LYS B N   1 
ATOM   5988 C  CA  . LYS B 1 274 ? 56.21674  -8.33651  -76.23333 1.000 23.72942  ?  274 LYS B CA  1 
ATOM   5989 C  C   . LYS B 1 274 ? 56.35441  -7.51071  -77.50611 1.000 25.05331  ?  274 LYS B C   1 
ATOM   5990 O  O   . LYS B 1 274 ? 56.85613  -6.38198  -77.46862 1.000 25.85280  ?  274 LYS B O   1 
ATOM   5991 C  CB  . LYS B 1 274 ? 57.32587  -9.38470  -76.14110 1.000 19.76521  ?  274 LYS B CB  1 
ATOM   5992 C  CG  . LYS B 1 274 ? 58.72841  -8.85209  -76.36158 1.000 26.19690  ?  274 LYS B CG  1 
ATOM   5993 C  CD  . LYS B 1 274 ? 59.76380  -9.92120  -76.04600 1.000 28.00617  ?  274 LYS B CD  1 
ATOM   5994 C  CE  . LYS B 1 274 ? 61.14417  -9.52599  -76.54021 1.000 21.18717  ?  274 LYS B CE  1 
ATOM   5995 N  NZ  . LYS B 1 274 ? 61.19960  -9.47471  -78.02757 1.000 22.15084  ?  274 LYS B NZ  1 
ATOM   5996 N  N   . SER B 1 275 ? 55.91674  -8.05692  -78.64346 1.000 27.88930  ?  275 SER B N   1 
ATOM   5997 C  CA  . SER B 1 275 ? 55.98879  -7.31559  -79.89978 1.000 26.09403  ?  275 SER B CA  1 
ATOM   5998 C  C   . SER B 1 275 ? 55.08874  -6.08513  -79.87076 1.000 30.70936  ?  275 SER B C   1 
ATOM   5999 O  O   . SER B 1 275 ? 55.49587  -4.99753  -80.30913 1.000 38.49976  ?  275 SER B O   1 
ATOM   6000 C  CB  . SER B 1 275 ? 55.61583  -8.22748  -81.06768 1.000 23.99342  ?  275 SER B CB  1 
ATOM   6001 O  OG  . SER B 1 275 ? 55.68302  -7.53007  -82.29865 1.000 39.00750  ?  275 SER B OG  1 
ATOM   6002 N  N   . VAL B 1 276 ? 53.86581  -6.23378  -79.35095 1.000 24.91431  ?  276 VAL B N   1 
ATOM   6003 C  CA  . VAL B 1 276 ? 52.96874  -5.08523  -79.24172 1.000 25.13918  ?  276 VAL B CA  1 
ATOM   6004 C  C   . VAL B 1 276 ? 53.57892  -4.01901  -78.33967 1.000 29.26902  ?  276 VAL B C   1 
ATOM   6005 O  O   . VAL B 1 276 ? 53.53084  -2.82056  -78.64689 1.000 34.76063  ?  276 VAL B O   1 
ATOM   6006 C  CB  . VAL B 1 276 ? 51.58315  -5.53283  -78.73951 1.000 25.01360  ?  276 VAL B CB  1 
ATOM   6007 C  CG1 . VAL B 1 276 ? 50.72039  -4.32643  -78.40001 1.000 21.54310  ?  276 VAL B CG1 1 
ATOM   6008 C  CG2 . VAL B 1 276 ? 50.89794  -6.39659  -79.78456 1.000 29.19420  ?  276 VAL B CG2 1 
ATOM   6009 N  N   . THR B 1 277 ? 54.16953  -4.43908  -77.21747 1.000 25.07444  ?  277 THR B N   1 
ATOM   6010 C  CA  . THR B 1 277 ? 54.78085  -3.49374  -76.28953 1.000 25.55272  ?  277 THR B CA  1 
ATOM   6011 C  C   . THR B 1 277 ? 55.96948  -2.78044  -76.92143 1.000 27.04611  ?  277 THR B C   1 
ATOM   6012 O  O   . THR B 1 277 ? 56.15633  -1.57746  -76.71698 1.000 27.14743  ?  277 THR B O   1 
ATOM   6013 C  CB  . THR B 1 277 ? 55.20299  -4.21889  -75.01070 1.000 24.50166  ?  277 THR B CB  1 
ATOM   6014 O  OG1 . THR B 1 277 ? 54.03708  -4.69460  -74.32772 1.000 23.46052  ?  277 THR B OG1 1 
ATOM   6015 C  CG2 . THR B 1 277 ? 55.97712  -3.28834  -74.08762 1.000 24.93413  ?  277 THR B CG2 1 
ATOM   6016 N  N   . GLU B 1 278 ? 56.79052  -3.50433  -77.68515 1.000 26.79671  ?  278 GLU B N   1 
ATOM   6017 C  CA  . GLU B 1 278 ? 57.92893  -2.86951  -78.34303 1.000 31.42424  ?  278 GLU B CA  1 
ATOM   6018 C  C   . GLU B 1 278 ? 57.47073  -1.83722  -79.36628 1.000 32.43231  ?  278 GLU B C   1 
ATOM   6019 O  O   . GLU B 1 278 ? 58.02087  -0.72884  -79.43184 1.000 30.27919  ?  278 GLU B O   1 
ATOM   6020 C  CB  . GLU B 1 278 ? 58.81432  -3.92839  -78.99967 1.000 34.28021  ?  278 GLU B CB  1 
ATOM   6021 C  CG  . GLU B 1 278 ? 59.58658  -4.78530  -78.00862 1.000 27.00321  ?  278 GLU B CG  1 
ATOM   6022 C  CD  . GLU B 1 278 ? 60.36756  -5.89507  -78.68207 1.000 30.24979  ?  278 GLU B CD  1 
ATOM   6023 O  OE1 . GLU B 1 278 ? 60.18571  -6.09428  -79.90184 1.000 31.69818  ?  278 GLU B OE1 1 
ATOM   6024 O  OE2 . GLU B 1 278 ? 61.16296  -6.56788  -77.99193 1.000 33.30797  -1 278 GLU B OE2 1 
ATOM   6025 N  N   . GLU B 1 279 ? 56.45383  -2.17538  -80.16565 1.000 37.65616  ?  279 GLU B N   1 
ATOM   6026 C  CA  . GLU B 1 279 ? 55.92335  -1.20184  -81.11767 1.000 45.55771  ?  279 GLU B CA  1 
ATOM   6027 C  C   . GLU B 1 279 ? 55.35876  0.02094   -80.40106 1.000 41.14136  ?  279 GLU B C   1 
ATOM   6028 O  O   . GLU B 1 279 ? 55.60356  1.16432   -80.81309 1.000 41.32403  ?  279 GLU B O   1 
ATOM   6029 C  CB  . GLU B 1 279 ? 54.85555  -1.85282  -81.99769 1.000 46.94135  ?  279 GLU B CB  1 
ATOM   6030 C  CG  . GLU B 1 279 ? 54.00998  -0.86302  -82.78607 1.000 57.71693  ?  279 GLU B CG  1 
ATOM   6031 C  CD  . GLU B 1 279 ? 54.83324  0.00985   -83.71653 1.000 69.74311  ?  279 GLU B CD  1 
ATOM   6032 O  OE1 . GLU B 1 279 ? 55.81632  -0.49249  -84.29943 1.000 73.67086  ?  279 GLU B OE1 1 
ATOM   6033 O  OE2 . GLU B 1 279 ? 54.49689  1.20298   -83.86372 1.000 62.62401  -1 279 GLU B OE2 1 
ATOM   6034 N  N   . PHE B 1 280 ? 54.61240  -0.20108  -79.31550 1.000 36.38477  ?  280 PHE B N   1 
ATOM   6035 C  CA  . PHE B 1 280 ? 54.03349  0.91039   -78.56814 1.000 33.71784  ?  280 PHE B CA  1 
ATOM   6036 C  C   . PHE B 1 280 ? 55.11741  1.79621   -77.96380 1.000 30.66662  ?  280 PHE B C   1 
ATOM   6037 O  O   . PHE B 1 280 ? 54.99966  3.02714   -77.97182 1.000 31.70013  ?  280 PHE B O   1 
ATOM   6038 C  CB  . PHE B 1 280 ? 53.10324  0.37158   -77.48170 1.000 29.65716  ?  280 PHE B CB  1 
ATOM   6039 C  CG  . PHE B 1 280 ? 52.26118  1.42570   -76.82340 1.000 33.69397  ?  280 PHE B CG  1 
ATOM   6040 C  CD1 . PHE B 1 280 ? 51.06701  1.83225   -77.39460 1.000 36.03943  ?  280 PHE B CD1 1 
ATOM   6041 C  CD2 . PHE B 1 280 ? 52.65734  2.00314   -75.62914 1.000 30.10080  ?  280 PHE B CD2 1 
ATOM   6042 C  CE1 . PHE B 1 280 ? 50.28663  2.79883   -76.79109 1.000 25.12792  ?  280 PHE B CE1 1 
ATOM   6043 C  CE2 . PHE B 1 280 ? 51.88115  2.96999   -75.02095 1.000 26.42191  ?  280 PHE B CE2 1 
ATOM   6044 C  CZ  . PHE B 1 280 ? 50.69395  3.36801   -75.60320 1.000 22.68961  ?  280 PHE B CZ  1 
ATOM   6045 N  N   . GLN B 1 281 ? 56.17948  1.18639   -77.43111 1.000 29.38982  ?  281 GLN B N   1 
ATOM   6046 C  CA  . GLN B 1 281 ? 57.29090  1.95857   -76.88578 1.000 32.82172  ?  281 GLN B CA  1 
ATOM   6047 C  C   . GLN B 1 281 ? 57.97347  2.77888   -77.97065 1.000 35.92568  ?  281 GLN B C   1 
ATOM   6048 O  O   . GLN B 1 281 ? 58.37813  3.92294   -77.73192 1.000 35.21297  ?  281 GLN B O   1 
ATOM   6049 C  CB  . GLN B 1 281 ? 58.29780  1.02820   -76.20817 1.000 35.38174  ?  281 GLN B CB  1 
ATOM   6050 C  CG  . GLN B 1 281 ? 57.82830  0.43843   -74.88815 1.000 38.64086  ?  281 GLN B CG  1 
ATOM   6051 C  CD  . GLN B 1 281 ? 58.74944  -0.65769  -74.38363 1.000 43.09527  ?  281 GLN B CD  1 
ATOM   6052 O  OE1 . GLN B 1 281 ? 59.42984  -1.32127  -75.16681 1.000 42.10500  ?  281 GLN B OE1 1 
ATOM   6053 N  NE2 . GLN B 1 281 ? 58.77898  -0.84983  -73.06974 1.000 40.48195  ?  281 GLN B NE2 1 
ATOM   6054 N  N   . ARG B 1 282 ? 58.12438  2.20662   -79.16787 1.000 41.42898  ?  282 ARG B N   1 
ATOM   6055 C  CA  . ARG B 1 282 ? 58.71183  2.96711   -80.26643 1.000 38.57306  ?  282 ARG B CA  1 
ATOM   6056 C  C   . ARG B 1 282 ? 57.84103  4.16006   -80.64234 1.000 30.10430  ?  282 ARG B C   1 
ATOM   6057 O  O   . ARG B 1 282 ? 58.35575  5.25309   -80.90627 1.000 31.53354  ?  282 ARG B O   1 
ATOM   6058 C  CB  . ARG B 1 282 ? 58.94059  2.06327   -81.47775 1.000 43.34125  ?  282 ARG B CB  1 
ATOM   6059 C  CG  . ARG B 1 282 ? 60.07653  1.07331   -81.29387 1.000 47.95940  ?  282 ARG B CG  1 
ATOM   6060 C  CD  . ARG B 1 282 ? 60.37894  0.32096   -82.57659 1.000 64.24252  ?  282 ARG B CD  1 
ATOM   6061 N  NE  . ARG B 1 282 ? 60.37205  -1.12094  -82.36352 1.000 76.07619  ?  282 ARG B NE  1 
ATOM   6062 C  CZ  . ARG B 1 282 ? 59.38682  -1.92694  -82.73397 1.000 68.29957  ?  282 ARG B CZ  1 
ATOM   6063 N  NH1 . ARG B 1 282 ? 58.32645  -1.46994  -83.37849 1.000 53.70479  ?  282 ARG B NH1 1 
ATOM   6064 N  NH2 . ARG B 1 282 ? 59.47022  -3.22487  -82.45523 1.000 65.41611  ?  282 ARG B NH2 1 
ATOM   6065 N  N   . GLU B 1 283 ? 56.51868  3.97400   -80.67098 1.000 30.56936  ?  283 GLU B N   1 
ATOM   6066 C  CA  . GLU B 1 283 ? 55.64187  5.07021   -81.07826 1.000 32.55542  ?  283 GLU B CA  1 
ATOM   6067 C  C   . GLU B 1 283 ? 55.62048  6.19726   -80.04975 1.000 30.42393  ?  283 GLU B C   1 
ATOM   6068 O  O   . GLU B 1 283 ? 55.67851  7.37648   -80.41668 1.000 30.42506  ?  283 GLU B O   1 
ATOM   6069 C  CB  . GLU B 1 283 ? 54.22756  4.55270   -81.33011 1.000 40.17460  ?  283 GLU B CB  1 
ATOM   6070 C  CG  . GLU B 1 283 ? 54.04624  3.89078   -82.68365 1.000 63.51723  ?  283 GLU B CG  1 
ATOM   6071 C  CD  . GLU B 1 283 ? 52.63652  3.38274   -82.88975 1.000 62.04722  ?  283 GLU B CD  1 
ATOM   6072 O  OE1 . GLU B 1 283 ? 51.83950  3.46721   -81.93561 1.000 59.38584  ?  283 GLU B OE1 1 
ATOM   6073 O  OE2 . GLU B 1 283 ? 52.32432  2.90217   -83.99967 1.000 61.20119  -1 283 GLU B OE2 1 
ATOM   6074 N  N   . TYR B 1 284 ? 55.54117  5.86351   -78.76060 1.000 32.04992  ?  284 TYR B N   1 
ATOM   6075 C  CA  . TYR B 1 284 ? 55.36681  6.85349   -77.69708 1.000 27.49891  ?  284 TYR B CA  1 
ATOM   6076 C  C   . TYR B 1 284 ? 56.55984  6.79981   -76.75067 1.000 31.15379  ?  284 TYR B C   1 
ATOM   6077 O  O   . TYR B 1 284 ? 56.57131  6.01262   -75.79043 1.000 31.26126  ?  284 TYR B O   1 
ATOM   6078 C  CB  . TYR B 1 284 ? 54.05387  6.62015   -76.95154 1.000 20.22500  ?  284 TYR B CB  1 
ATOM   6079 C  CG  . TYR B 1 284 ? 52.83815  6.63658   -77.85390 1.000 21.11719  ?  284 TYR B CG  1 
ATOM   6080 C  CD1 . TYR B 1 284 ? 52.19554  7.82715   -78.16503 1.000 31.53281  ?  284 TYR B CD1 1 
ATOM   6081 C  CD2 . TYR B 1 284 ? 52.33812  5.46244   -78.40035 1.000 34.08519  ?  284 TYR B CD2 1 
ATOM   6082 C  CE1 . TYR B 1 284 ? 51.08592  7.84798   -78.99114 1.000 28.65296  ?  284 TYR B CE1 1 
ATOM   6083 C  CE2 . TYR B 1 284 ? 51.22991  5.47316   -79.22844 1.000 40.30393  ?  284 TYR B CE2 1 
ATOM   6084 C  CZ  . TYR B 1 284 ? 50.60811  6.66811   -79.52011 1.000 34.14753  ?  284 TYR B CZ  1 
ATOM   6085 O  OH  . TYR B 1 284 ? 49.50516  6.68119   -80.34344 1.000 35.66659  ?  284 TYR B OH  1 
ATOM   6086 N  N   . PRO B 1 285 ? 57.58772  7.62075   -76.98571 1.000 23.99658  ?  285 PRO B N   1 
ATOM   6087 C  CA  . PRO B 1 285 ? 58.77537  7.59412   -76.11334 1.000 21.11366  ?  285 PRO B CA  1 
ATOM   6088 C  C   . PRO B 1 285 ? 58.50422  7.99906   -74.67371 1.000 26.08261  ?  285 PRO B C   1 
ATOM   6089 O  O   . PRO B 1 285 ? 59.26572  7.59702   -73.78533 1.000 33.34184  ?  285 PRO B O   1 
ATOM   6090 C  CB  . PRO B 1 285 ? 59.73308  8.58052   -76.79583 1.000 18.29730  ?  285 PRO B CB  1 
ATOM   6091 C  CG  . PRO B 1 285 ? 59.26387  8.64515   -78.21616 1.000 28.09582  ?  285 PRO B CG  1 
ATOM   6092 C  CD  . PRO B 1 285 ? 57.77595  8.49884   -78.15087 1.000 23.89114  ?  285 PRO B CD  1 
ATOM   6093 N  N   . ASP B 1 286 ? 57.45891  8.78571   -74.40874 1.000 23.66017  ?  286 ASP B N   1 
ATOM   6094 C  CA  . ASP B 1 286 ? 57.13505  9.15400   -73.03513 1.000 25.39329  ?  286 ASP B CA  1 
ATOM   6095 C  C   . ASP B 1 286 ? 56.64957  7.96883   -72.21232 1.000 34.99765  ?  286 ASP B C   1 
ATOM   6096 O  O   . ASP B 1 286 ? 56.55240  8.08452   -70.98528 1.000 30.48336  ?  286 ASP B O   1 
ATOM   6097 C  CB  . ASP B 1 286 ? 56.08077  10.26515  -73.01419 1.000 29.57249  ?  286 ASP B CB  1 
ATOM   6098 C  CG  . ASP B 1 286 ? 54.78754  9.86390   -73.70360 1.000 37.35966  ?  286 ASP B CG  1 
ATOM   6099 O  OD1 . ASP B 1 286 ? 54.82068  9.54238   -74.90987 1.000 34.83634  ?  286 ASP B OD1 1 
ATOM   6100 O  OD2 . ASP B 1 286 ? 53.73276  9.86884   -73.03482 1.000 52.25173  -1 286 ASP B OD2 1 
ATOM   6101 N  N   . PHE B 1 287 ? 56.34702  6.84490   -72.85582 1.000 43.47434  ?  287 PHE B N   1 
ATOM   6102 C  CA  . PHE B 1 287 ? 55.90855  5.64527   -72.16001 1.000 42.70973  ?  287 PHE B CA  1 
ATOM   6103 C  C   . PHE B 1 287 ? 57.10668  4.88914   -71.59840 1.000 33.24632  ?  287 PHE B C   1 
ATOM   6104 O  O   . PHE B 1 287 ? 58.14696  4.77022   -72.25249 1.000 32.42873  ?  287 PHE B O   1 
ATOM   6105 C  CB  . PHE B 1 287 ? 55.11877  4.75087   -73.11678 1.000 29.37278  ?  287 PHE B CB  1 
ATOM   6106 C  CG  . PHE B 1 287 ? 54.23298  3.75412   -72.43123 1.000 28.04839  ?  287 PHE B CG  1 
ATOM   6107 C  CD1 . PHE B 1 287 ? 53.11966  4.17209   -71.72083 1.000 29.93669  ?  287 PHE B CD1 1 
ATOM   6108 C  CD2 . PHE B 1 287 ? 54.49769  2.39799   -72.51646 1.000 28.75239  ?  287 PHE B CD2 1 
ATOM   6109 C  CE1 . PHE B 1 287 ? 52.29517  3.25663   -71.09397 1.000 35.40534  ?  287 PHE B CE1 1 
ATOM   6110 C  CE2 . PHE B 1 287 ? 53.67565  1.47700   -71.89319 1.000 34.84829  ?  287 PHE B CE2 1 
ATOM   6111 C  CZ  . PHE B 1 287 ? 52.57403  1.90678   -71.18027 1.000 39.48099  ?  287 PHE B CZ  1 
ATOM   6112 N  N   . ILE B 1 288 ? 56.95856  4.38306   -70.37412 1.000 28.00639  ?  288 ILE B N   1 
ATOM   6113 C  CA  . ILE B 1 288 ? 58.02215  3.59045   -69.76558 1.000 31.91594  ?  288 ILE B CA  1 
ATOM   6114 C  C   . ILE B 1 288 ? 57.97783  2.15356   -70.26949 1.000 36.99694  ?  288 ILE B C   1 
ATOM   6115 O  O   . ILE B 1 288 ? 58.98262  1.62581   -70.76017 1.000 33.72612  ?  288 ILE B O   1 
ATOM   6116 C  CB  . ILE B 1 288 ? 57.93671  3.65687   -68.23049 1.000 31.11112  ?  288 ILE B CB  1 
ATOM   6117 C  CG1 . ILE B 1 288 ? 58.13901  5.09536   -67.75321 1.000 28.70928  ?  288 ILE B CG1 1 
ATOM   6118 C  CG2 . ILE B 1 288 ? 58.97268  2.73839   -67.60446 1.000 26.19488  ?  288 ILE B CG2 1 
ATOM   6119 C  CD1 . ILE B 1 288 ? 58.06546  5.25740   -66.25377 1.000 27.78308  ?  288 ILE B CD1 1 
ATOM   6120 N  N   . GLY B 1 289 ? 56.82916  1.49760   -70.16482 1.000 39.88823  ?  289 GLY B N   1 
ATOM   6121 C  CA  . GLY B 1 289 ? 56.66736  0.19786   -70.78257 1.000 37.78291  ?  289 GLY B CA  1 
ATOM   6122 C  C   . GLY B 1 289 ? 55.74896  -0.71719  -69.99419 1.000 35.88720  ?  289 GLY B C   1 
ATOM   6123 O  O   . GLY B 1 289 ? 55.03821  -0.29877  -69.08128 1.000 31.79960  ?  289 GLY B O   1 
ATOM   6124 N  N   . ALA B 1 290 ? 55.78488  -1.99162  -70.38489 1.000 30.86842  ?  290 ALA B N   1 
ATOM   6125 C  CA  . ALA B 1 290 ? 54.91860  -3.02043  -69.83316 1.000 22.41930  ?  290 ALA B CA  1 
ATOM   6126 C  C   . ALA B 1 290 ? 55.72937  -4.27278  -69.53822 1.000 25.99379  ?  290 ALA B C   1 
ATOM   6127 O  O   . ALA B 1 290 ? 56.68377  -4.59726  -70.24943 1.000 25.25109  ?  290 ALA B O   1 
ATOM   6128 C  CB  . ALA B 1 290 ? 53.77640  -3.36797  -70.79567 1.000 22.96355  ?  290 ALA B CB  1 
ATOM   6129 N  N   . LYS B 1 291 ? 55.33605  -4.97193  -68.47580 1.000 30.94829  ?  291 LYS B N   1 
ATOM   6130 C  CA  . LYS B 1 291 ? 55.90693  -6.26733  -68.13158 1.000 28.57406  ?  291 LYS B CA  1 
ATOM   6131 C  C   . LYS B 1 291 ? 54.77317  -7.19682  -67.71565 1.000 25.47234  ?  291 LYS B C   1 
ATOM   6132 O  O   . LYS B 1 291 ? 53.69508  -6.74862  -67.31952 1.000 20.69081  ?  291 LYS B O   1 
ATOM   6133 C  CB  . LYS B 1 291 ? 56.97509  -6.14271  -67.03402 1.000 26.09872  ?  291 LYS B CB  1 
ATOM   6134 C  CG  . LYS B 1 291 ? 58.11432  -5.19904  -67.41207 1.000 26.71526  ?  291 LYS B CG  1 
ATOM   6135 C  CD  . LYS B 1 291 ? 59.38149  -5.46395  -66.62378 1.000 33.64671  ?  291 LYS B CD  1 
ATOM   6136 C  CE  . LYS B 1 291 ? 60.52405  -4.59395  -67.12416 1.000 30.67141  ?  291 LYS B CE  1 
ATOM   6137 N  NZ  . LYS B 1 291 ? 61.84041  -5.08047  -66.63127 1.000 31.54080  ?  291 LYS B NZ  1 
ATOM   6138 N  N   . ILE B 1 292 ? 55.01500  -8.50191  -67.83251 1.000 23.97637  ?  292 ILE B N   1 
ATOM   6139 C  CA  . ILE B 1 292 ? 53.95676  -9.50350  -67.76582 1.000 19.73541  ?  292 ILE B CA  1 
ATOM   6140 C  C   . ILE B 1 292 ? 54.23641  -10.48804 -66.63786 1.000 21.31499  ?  292 ILE B C   1 
ATOM   6141 O  O   . ILE B 1 292 ? 55.38190  -10.89619 -66.41924 1.000 21.54427  ?  292 ILE B O   1 
ATOM   6142 C  CB  . ILE B 1 292 ? 53.80429  -10.24445 -69.11092 1.000 19.33704  ?  292 ILE B CB  1 
ATOM   6143 C  CG1 . ILE B 1 292 ? 53.50467  -9.24921  -70.23152 1.000 19.08998  ?  292 ILE B CG1 1 
ATOM   6144 C  CG2 . ILE B 1 292 ? 52.70248  -11.29052 -69.03452 1.000 20.85540  ?  292 ILE B CG2 1 
ATOM   6145 C  CD1 . ILE B 1 292 ? 52.25541  -8.43041  -70.00623 1.000 17.86354  ?  292 ILE B CD1 1 
ATOM   6146 N  N   . ILE B 1 293 ? 53.17637  -10.86101 -65.92347 1.000 22.41425  ?  293 ILE B N   1 
ATOM   6147 C  CA  . ILE B 1 293 ? 53.19824  -11.89556 -64.89737 1.000 22.42162  ?  293 ILE B CA  1 
ATOM   6148 C  C   . ILE B 1 293 ? 52.27391  -13.01734 -65.35084 1.000 25.17397  ?  293 ILE B C   1 
ATOM   6149 O  O   . ILE B 1 293 ? 51.22809  -12.75742 -65.95489 1.000 32.50959  ?  293 ILE B O   1 
ATOM   6150 C  CB  . ILE B 1 293 ? 52.75566  -11.33991 -63.52683 1.000 23.05243  ?  293 ILE B CB  1 
ATOM   6151 C  CG1 . ILE B 1 293 ? 53.60576  -10.12739 -63.14162 1.000 29.75251  ?  293 ILE B CG1 1 
ATOM   6152 C  CG2 . ILE B 1 293 ? 52.83129  -12.41557 -62.45262 1.000 21.78996  ?  293 ILE B CG2 1 
ATOM   6153 C  CD1 . ILE B 1 293 ? 53.11073  -9.40243  -61.90904 1.000 29.88824  ?  293 ILE B CD1 1 
ATOM   6154 N  N   . LEU B 1 294 ? 52.67239  -14.26222 -65.09745 1.000 21.36925  ?  294 LEU B N   1 
ATOM   6155 C  CA  . LEU B 1 294 ? 51.85454  -15.41723 -65.45189 1.000 22.01530  ?  294 LEU B CA  1 
ATOM   6156 C  C   . LEU B 1 294 ? 50.92681  -15.75639 -64.29209 1.000 23.99984  ?  294 LEU B C   1 
ATOM   6157 O  O   . LEU B 1 294 ? 51.39031  -16.07175 -63.19126 1.000 22.93312  ?  294 LEU B O   1 
ATOM   6158 C  CB  . LEU B 1 294 ? 52.72280  -16.62281 -65.80478 1.000 22.20642  ?  294 LEU B CB  1 
ATOM   6159 C  CG  . LEU B 1 294 ? 51.95030  -17.91812 -66.06793 1.000 15.73578  ?  294 LEU B CG  1 
ATOM   6160 C  CD1 . LEU B 1 294 ? 50.96343  -17.73254 -67.20940 1.000 15.28614  ?  294 LEU B CD1 1 
ATOM   6161 C  CD2 . LEU B 1 294 ? 52.89993  -19.06927 -66.35809 1.000 15.30494  ?  294 LEU B CD2 1 
ATOM   6162 N  N   . SER B 1 295 ? 49.62301  -15.70741 -64.54320 1.000 21.71625  ?  295 SER B N   1 
ATOM   6163 C  CA  . SER B 1 295 ? 48.61450  -15.96177 -63.52492 1.000 20.43314  ?  295 SER B CA  1 
ATOM   6164 C  C   . SER B 1 295 ? 47.92825  -17.29210 -63.79952 1.000 16.66252  ?  295 SER B C   1 
ATOM   6165 O  O   . SER B 1 295 ? 47.41308  -17.51710 -64.90007 1.000 23.67270  ?  295 SER B O   1 
ATOM   6166 C  CB  . SER B 1 295 ? 47.58046  -14.83321 -63.47864 1.000 19.50163  ?  295 SER B CB  1 
ATOM   6167 O  OG  . SER B 1 295 ? 46.83390  -14.76634 -64.68132 1.000 19.26121  ?  295 SER B OG  1 
ATOM   6168 N  N   . GLY B 1 296 ? 47.93270  -18.16943 -62.80092 1.000 11.96021  ?  296 GLY B N   1 
ATOM   6169 C  CA  . GLY B 1 296 ? 47.17718  -19.40270 -62.86240 1.000 14.22540  ?  296 GLY B CA  1 
ATOM   6170 C  C   . GLY B 1 296 ? 46.00238  -19.36354 -61.90890 1.000 23.68080  ?  296 GLY B C   1 
ATOM   6171 O  O   . GLY B 1 296 ? 45.99512  -18.56722 -60.96720 1.000 21.88808  ?  296 GLY B O   1 
ATOM   6172 N  N   . LEU B 1 297 ? 45.00495  -20.21160 -62.13382 1.000 23.66936  ?  297 LEU B N   1 
ATOM   6173 C  CA  . LEU B 1 297 ? 43.80812  -20.22219 -61.30581 1.000 17.95631  ?  297 LEU B CA  1 
ATOM   6174 C  C   . LEU B 1 297 ? 43.98642  -21.17636 -60.13200 1.000 22.11805  ?  297 LEU B C   1 
ATOM   6175 O  O   . LEU B 1 297 ? 44.47877  -22.29636 -60.29557 1.000 21.37897  ?  297 LEU B O   1 
ATOM   6176 C  CB  . LEU B 1 297 ? 42.59048  -20.61687 -62.14012 1.000 18.21689  ?  297 LEU B CB  1 
ATOM   6177 C  CG  . LEU B 1 297 ? 42.30417  -19.64516 -63.28775 1.000 16.43839  ?  297 LEU B CG  1 
ATOM   6178 C  CD1 . LEU B 1 297 ? 41.16767  -20.14097 -64.16731 1.000 15.75267  ?  297 LEU B CD1 1 
ATOM   6179 C  CD2 . LEU B 1 297 ? 41.99999  -18.25654 -62.74333 1.000 17.90805  ?  297 LEU B CD2 1 
ATOM   6180 N  N   . ARG B 1 298 ? 43.58105  -20.72247 -58.94272 1.000 26.23551  ?  298 ARG B N   1 
ATOM   6181 C  CA  . ARG B 1 298 ? 43.82559  -21.44877 -57.70180 1.000 25.33596  ?  298 ARG B CA  1 
ATOM   6182 C  C   . ARG B 1 298 ? 42.80489  -22.55252 -57.42962 1.000 26.16799  ?  298 ARG B C   1 
ATOM   6183 O  O   . ARG B 1 298 ? 42.71440  -23.01708 -56.28675 1.000 29.99019  ?  298 ARG B O   1 
ATOM   6184 C  CB  . ARG B 1 298 ? 43.86902  -20.47780 -56.51687 1.000 22.83721  ?  298 ARG B CB  1 
ATOM   6185 C  CG  . ARG B 1 298 ? 42.57831  -19.71158 -56.27783 1.000 26.69039  ?  298 ARG B CG  1 
ATOM   6186 C  CD  . ARG B 1 298 ? 42.65249  -18.86862 -55.00824 1.000 20.75416  ?  298 ARG B CD  1 
ATOM   6187 N  NE  . ARG B 1 298 ? 43.84147  -18.02442 -54.97257 1.000 21.63248  ?  298 ARG B NE  1 
ATOM   6188 C  CZ  . ARG B 1 298 ? 44.85411  -18.18606 -54.13091 1.000 27.97647  ?  298 ARG B CZ  1 
ATOM   6189 N  NH1 . ARG B 1 298 ? 44.84676  -19.14100 -53.21507 1.000 23.83218  ?  298 ARG B NH1 1 
ATOM   6190 N  NH2 . ARG B 1 298 ? 45.89837  -17.36535 -54.20666 1.000 25.20202  ?  298 ARG B NH2 1 
ATOM   6191 N  N   . PHE B 1 299 ? 42.03376  -22.97958 -58.42872 1.000 24.60042  ?  299 PHE B N   1 
ATOM   6192 C  CA  . PHE B 1 299 ? 41.17677  -24.14999 -58.29454 1.000 23.42207  ?  299 PHE B CA  1 
ATOM   6193 C  C   . PHE B 1 299 ? 41.58762  -25.28408 -59.22261 1.000 22.61635  ?  299 PHE B C   1 
ATOM   6194 O  O   . PHE B 1 299 ? 40.91838  -26.32248 -59.24829 1.000 25.89946  ?  299 PHE B O   1 
ATOM   6195 C  CB  . PHE B 1 299 ? 39.70733  -23.77578 -58.53579 1.000 20.69882  ?  299 PHE B CB  1 
ATOM   6196 C  CG  . PHE B 1 299 ? 39.41201  -23.30170 -59.93373 1.000 20.09706  ?  299 PHE B CG  1 
ATOM   6197 C  CD1 . PHE B 1 299 ? 39.54313  -21.96433 -60.26999 1.000 20.16145  ?  299 PHE B CD1 1 
ATOM   6198 C  CD2 . PHE B 1 299 ? 38.98062  -24.19157 -60.90499 1.000 32.59769  ?  299 PHE B CD2 1 
ATOM   6199 C  CE1 . PHE B 1 299 ? 39.26211  -21.52651 -61.55174 1.000 16.52743  ?  299 PHE B CE1 1 
ATOM   6200 C  CE2 . PHE B 1 299 ? 38.70161  -23.76046 -62.18851 1.000 31.65983  ?  299 PHE B CE2 1 
ATOM   6201 C  CZ  . PHE B 1 299 ? 38.84260  -22.42641 -62.51218 1.000 21.46132  ?  299 PHE B CZ  1 
ATOM   6202 N  N   . LYS B 1 300 ? 42.67054  -25.11737 -59.97573 1.000 25.41045  ?  300 LYS B N   1 
ATOM   6203 C  CA  . LYS B 1 300 ? 43.12570  -26.13876 -60.90191 1.000 27.66089  ?  300 LYS B CA  1 
ATOM   6204 C  C   . LYS B 1 300 ? 43.83328  -27.26461 -60.15122 1.000 30.50729  ?  300 LYS B C   1 
ATOM   6205 O  O   . LYS B 1 300 ? 44.08982  -27.18735 -58.94647 1.000 26.66377  ?  300 LYS B O   1 
ATOM   6206 C  CB  . LYS B 1 300 ? 44.05282  -25.53083 -61.95441 1.000 24.54477  ?  300 LYS B CB  1 
ATOM   6207 C  CG  . LYS B 1 300 ? 43.43456  -24.37659 -62.73010 1.000 25.50444  ?  300 LYS B CG  1 
ATOM   6208 C  CD  . LYS B 1 300 ? 43.34402  -24.68239 -64.21691 1.000 21.34647  ?  300 LYS B CD  1 
ATOM   6209 C  CE  . LYS B 1 300 ? 42.61754  -23.57224 -64.96059 1.000 17.37569  ?  300 LYS B CE  1 
ATOM   6210 N  NZ  . LYS B 1 300 ? 42.53854  -23.83626 -66.42275 1.000 16.42953  ?  300 LYS B NZ  1 
ATOM   6211 N  N   . SER B 1 301 ? 44.13754  -28.33074 -60.88461 1.000 39.95440  ?  301 SER B N   1 
ATOM   6212 C  CA  . SER B 1 301 ? 44.84976  -29.46092 -60.31011 1.000 28.04464  ?  301 SER B CA  1 
ATOM   6213 C  C   . SER B 1 301 ? 46.28100  -29.07428 -59.95666 1.000 23.98413  ?  301 SER B C   1 
ATOM   6214 O  O   . SER B 1 301 ? 46.88336  -28.19343 -60.57627 1.000 24.91461  ?  301 SER B O   1 
ATOM   6215 C  CB  . SER B 1 301 ? 44.85305  -30.63891 -61.28257 1.000 20.46008  ?  301 SER B CB  1 
ATOM   6216 O  OG  . SER B 1 301 ? 45.39986  -30.26569 -62.53539 1.000 12.61932  ?  301 SER B OG  1 
ATOM   6217 N  N   . GLN B 1 302 ? 46.82329  -29.74850 -58.93935 1.000 23.52272  ?  302 GLN B N   1 
ATOM   6218 C  CA  . GLN B 1 302 ? 48.20023  -29.49277 -58.53095 1.000 22.01399  ?  302 GLN B CA  1 
ATOM   6219 C  C   . GLN B 1 302 ? 49.18323  -29.80791 -59.65024 1.000 23.62562  ?  302 GLN B C   1 
ATOM   6220 O  O   . GLN B 1 302 ? 50.21660  -29.14194 -59.77258 1.000 26.22473  ?  302 GLN B O   1 
ATOM   6221 C  CB  . GLN B 1 302 ? 48.53165  -30.30827 -57.28248 1.000 22.76986  ?  302 GLN B CB  1 
ATOM   6222 C  CG  . GLN B 1 302 ? 47.59921  -30.04393 -56.11456 1.000 23.60481  ?  302 GLN B CG  1 
ATOM   6223 C  CD  . GLN B 1 302 ? 47.51570  -31.21821 -55.16249 1.000 35.16521  ?  302 GLN B CD  1 
ATOM   6224 O  OE1 . GLN B 1 302 ? 46.91351  -32.24527 -55.47817 1.000 40.85825  ?  302 GLN B OE1 1 
ATOM   6225 N  NE2 . GLN B 1 302 ? 48.12314  -31.07507 -53.99021 1.000 30.24594  ?  302 GLN B NE2 1 
ATOM   6226 N  N   . GLU B 1 303 ? 48.88260  -30.81768 -60.47108 1.000 24.41934  ?  303 GLU B N   1 
ATOM   6227 C  CA  . GLU B 1 303 ? 49.73206  -31.12406 -61.61812 1.000 20.91854  ?  303 GLU B CA  1 
ATOM   6228 C  C   . GLU B 1 303 ? 49.73117  -29.98272 -62.62887 1.000 19.50523  ?  303 GLU B C   1 
ATOM   6229 O  O   . GLU B 1 303 ? 50.78506  -29.61317 -63.16280 1.000 21.37773  ?  303 GLU B O   1 
ATOM   6230 C  CB  . GLU B 1 303 ? 49.26695  -32.42442 -62.27398 1.000 32.67011  ?  303 GLU B CB  1 
ATOM   6231 C  CG  . GLU B 1 303 ? 49.96533  -32.75525 -63.58185 1.000 47.46500  ?  303 GLU B CG  1 
ATOM   6232 C  CD  . GLU B 1 303 ? 49.30854  -33.90981 -64.31405 1.000 59.75243  ?  303 GLU B CD  1 
ATOM   6233 O  OE1 . GLU B 1 303 ? 48.51325  -34.64020 -63.68464 1.000 60.84367  ?  303 GLU B OE1 1 
ATOM   6234 O  OE2 . GLU B 1 303 ? 49.58214  -34.08235 -65.52075 1.000 64.61716  -1 303 GLU B OE2 1 
ATOM   6235 N  N   . GLU B 1 304 ? 48.55455  -29.41518 -62.90891 1.000 22.08946  ?  304 GLU B N   1 
ATOM   6236 C  CA  . GLU B 1 304 ? 48.47729  -28.29096 -63.83676 1.000 23.55646  ?  304 GLU B CA  1 
ATOM   6237 C  C   . GLU B 1 304 ? 49.22838  -27.08081 -63.29875 1.000 21.24180  ?  304 GLU B C   1 
ATOM   6238 O  O   . GLU B 1 304 ? 49.93378  -26.39639 -64.04752 1.000 19.15788  ?  304 GLU B O   1 
ATOM   6239 C  CB  . GLU B 1 304 ? 47.01447  -27.94024 -64.11920 1.000 28.13964  ?  304 GLU B CB  1 
ATOM   6240 C  CG  . GLU B 1 304 ? 46.78652  -26.54836 -64.71222 1.000 44.47777  ?  304 GLU B CG  1 
ATOM   6241 C  CD  . GLU B 1 304 ? 47.19521  -26.43097 -66.17481 1.000 45.53602  ?  304 GLU B CD  1 
ATOM   6242 O  OE1 . GLU B 1 304 ? 47.70793  -27.41691 -66.74609 1.000 48.73918  ?  304 GLU B OE1 1 
ATOM   6243 O  OE2 . GLU B 1 304 ? 46.99586  -25.34285 -66.75709 1.000 34.78677  -1 304 GLU B OE2 1 
ATOM   6244 N  N   . ILE B 1 305 ? 49.09685  -26.80652 -61.99980 1.000 20.70278  ?  305 ILE B N   1 
ATOM   6245 C  CA  . ILE B 1 305 ? 49.81121  -25.68287 -61.40304 1.000 16.78100  ?  305 ILE B CA  1 
ATOM   6246 C  C   . ILE B 1 305 ? 51.31627  -25.92225 -61.44288 1.000 20.33586  ?  305 ILE B C   1 
ATOM   6247 O  O   . ILE B 1 305 ? 52.09708  -24.99687 -61.68541 1.000 19.73402  ?  305 ILE B O   1 
ATOM   6248 C  CB  . ILE B 1 305 ? 49.30605  -25.43235 -59.97078 1.000 15.41642  ?  305 ILE B CB  1 
ATOM   6249 C  CG1 . ILE B 1 305 ? 47.80589  -25.12971 -59.98751 1.000 21.80886  ?  305 ILE B CG1 1 
ATOM   6250 C  CG2 . ILE B 1 305 ? 50.07148  -24.29011 -59.32030 1.000 15.34278  ?  305 ILE B CG2 1 
ATOM   6251 C  CD1 . ILE B 1 305 ? 47.42316  -23.97056 -60.88350 1.000 20.89774  ?  305 ILE B CD1 1 
ATOM   6252 N  N   . LEU B 1 306 ? 51.74779  -27.16423 -61.20935 1.000 23.75987  ?  306 LEU B N   1 
ATOM   6253 C  CA  . LEU B 1 306 ? 53.16895  -27.49149 -61.29683 1.000 20.34833  ?  306 LEU B CA  1 
ATOM   6254 C  C   . LEU B 1 306 ? 53.70159  -27.28815 -62.71059 1.000 20.02128  ?  306 LEU B C   1 
ATOM   6255 O  O   . LEU B 1 306 ? 54.79546  -26.73856 -62.90260 1.000 25.30161  ?  306 LEU B O   1 
ATOM   6256 C  CB  . LEU B 1 306 ? 53.39319  -28.93289 -60.84014 1.000 19.15235  ?  306 LEU B CB  1 
ATOM   6257 C  CG  . LEU B 1 306 ? 54.73614  -29.58446 -61.17057 1.000 21.57642  ?  306 LEU B CG  1 
ATOM   6258 C  CD1 . LEU B 1 306 ? 55.87044  -28.92598 -60.39784 1.000 23.06720  ?  306 LEU B CD1 1 
ATOM   6259 C  CD2 . LEU B 1 306 ? 54.68030  -31.07815 -60.89078 1.000 25.30461  ?  306 LEU B CD2 1 
ATOM   6260 N  N   . ASN B 1 307 ? 52.94311  -27.72812 -63.71527 1.000 19.78633  ?  307 ASN B N   1 
ATOM   6261 C  CA  . ASN B 1 307 ? 53.36684  -27.51813 -65.09492 1.000 20.99746  ?  307 ASN B CA  1 
ATOM   6262 C  C   . ASN B 1 307 ? 53.39447  -26.03318 -65.43834 1.000 26.13876  ?  307 ASN B C   1 
ATOM   6263 O  O   . ASN B 1 307 ? 54.27422  -25.57698 -66.17789 1.000 24.94637  ?  307 ASN B O   1 
ATOM   6264 C  CB  . ASN B 1 307 ? 52.45140  -28.28094 -66.04977 1.000 24.43723  ?  307 ASN B CB  1 
ATOM   6265 C  CG  . ASN B 1 307 ? 53.21051  -28.90954 -67.19905 1.000 37.05917  ?  307 ASN B CG  1 
ATOM   6266 O  OD1 . ASN B 1 307 ? 53.55364  -28.23890 -68.17274 1.000 35.89403  ?  307 ASN B OD1 1 
ATOM   6267 N  ND2 . ASN B 1 307 ? 53.48114  -30.20555 -67.09011 1.000 43.52117  ?  307 ASN B ND2 1 
ATOM   6268 N  N   . GLU B 1 308 ? 52.44067  -25.26332 -64.90682 1.000 25.45099  ?  308 GLU B N   1 
ATOM   6269 C  CA  . GLU B 1 308 ? 52.45869  -23.81750 -65.10359 1.000 18.14116  ?  308 GLU B CA  1 
ATOM   6270 C  C   . GLU B 1 308 ? 53.68562  -23.19075 -64.45573 1.000 17.47808  ?  308 GLU B C   1 
ATOM   6271 O  O   . GLU B 1 308 ? 54.27151  -22.25235 -65.00231 1.000 16.42055  ?  308 GLU B O   1 
ATOM   6272 C  CB  . GLU B 1 308 ? 51.18016  -23.19052 -64.54761 1.000 15.77538  ?  308 GLU B CB  1 
ATOM   6273 C  CG  . GLU B 1 308 ? 49.93025  -23.50967 -65.34927 1.000 21.16086  ?  308 GLU B CG  1 
ATOM   6274 C  CD  . GLU B 1 308 ? 48.68961  -22.85236 -64.77750 1.000 24.08922  ?  308 GLU B CD  1 
ATOM   6275 O  OE1 . GLU B 1 308 ? 48.83509  -21.92390 -63.95672 1.000 17.05263  ?  308 GLU B OE1 1 
ATOM   6276 O  OE2 . GLU B 1 308 ? 47.56929  -23.26477 -65.14576 1.000 26.75700  -1 308 GLU B OE2 1 
ATOM   6277 N  N   . VAL B 1 309 ? 54.08075  -23.68862 -63.28259 1.000 20.97685  ?  309 VAL B N   1 
ATOM   6278 C  CA  . VAL B 1 309 ? 55.29202  -23.19538 -62.63054 1.000 22.43387  ?  309 VAL B CA  1 
ATOM   6279 C  C   . VAL B 1 309 ? 56.51520  -23.49466 -63.48835 1.000 22.59771  ?  309 VAL B C   1 
ATOM   6280 O  O   . VAL B 1 309 ? 57.41426  -22.65717 -63.62809 1.000 27.39751  ?  309 VAL B O   1 
ATOM   6281 C  CB  . VAL B 1 309 ? 55.42644  -23.79532 -61.21722 1.000 16.69419  ?  309 VAL B CB  1 
ATOM   6282 C  CG1 . VAL B 1 309 ? 56.78683  -23.46236 -60.62208 1.000 16.13906  ?  309 VAL B CG1 1 
ATOM   6283 C  CG2 . VAL B 1 309 ? 54.31783  -23.28077 -60.31310 1.000 11.63507  ?  309 VAL B CG2 1 
ATOM   6284 N  N   . LYS B 1 310 ? 56.57134  -24.69453 -64.07185 1.000 20.10076  ?  310 LYS B N   1 
ATOM   6285 C  CA  . LYS B 1 310 ? 57.68366  -25.02961 -64.96062 1.000 19.47568  ?  310 LYS B CA  1 
ATOM   6286 C  C   . LYS B 1 310 ? 57.70831  -24.11988 -66.18707 1.000 23.97319  ?  310 LYS B C   1 
ATOM   6287 O  O   . LYS B 1 310 ? 58.77645  -23.64996 -66.60662 1.000 24.87811  ?  310 LYS B O   1 
ATOM   6288 C  CB  . LYS B 1 310 ? 57.59692  -26.49675 -65.38084 1.000 16.56934  ?  310 LYS B CB  1 
ATOM   6289 C  CG  . LYS B 1 310 ? 57.71325  -27.48066 -64.22755 1.000 24.26899  ?  310 LYS B CG  1 
ATOM   6290 C  CD  . LYS B 1 310 ? 57.67526  -28.92012 -64.71811 1.000 30.79159  ?  310 LYS B CD  1 
ATOM   6291 C  CE  . LYS B 1 310 ? 57.81635  -29.90078 -63.56451 1.000 28.88738  ?  310 LYS B CE  1 
ATOM   6292 N  NZ  . LYS B 1 310 ? 57.79913  -31.31596 -64.02820 1.000 23.49686  ?  310 LYS B NZ  1 
ATOM   6293 N  N   . ILE B 1 311 ? 56.53720  -23.86063 -66.77361 1.000 24.44388  ?  311 ILE B N   1 
ATOM   6294 C  CA  . ILE B 1 311 ? 56.45274  -22.95808 -67.91994 1.000 22.74537  ?  311 ILE B CA  1 
ATOM   6295 C  C   . ILE B 1 311 ? 56.90101  -21.55641 -67.52632 1.000 23.36345  ?  311 ILE B C   1 
ATOM   6296 O  O   . ILE B 1 311 ? 57.59257  -20.87100 -68.28881 1.000 27.40645  ?  311 ILE B O   1 
ATOM   6297 C  CB  . ILE B 1 311 ? 55.02291  -22.95546 -68.49417 1.000 16.67110  ?  311 ILE B CB  1 
ATOM   6298 C  CG1 . ILE B 1 311 ? 54.67160  -24.32815 -69.06824 1.000 14.91065  ?  311 ILE B CG1 1 
ATOM   6299 C  CG2 . ILE B 1 311 ? 54.86974  -21.88005 -69.55934 1.000 17.20100  ?  311 ILE B CG2 1 
ATOM   6300 C  CD1 . ILE B 1 311 ? 53.23473  -24.44474 -69.52739 1.000 14.06183  ?  311 ILE B CD1 1 
ATOM   6301 N  N   . ALA B 1 312 ? 56.50498  -21.10581 -66.33457 1.000 17.08632  ?  312 ALA B N   1 
ATOM   6302 C  CA  . ALA B 1 312 ? 56.91588  -19.79133 -65.85733 1.000 20.04540  ?  312 ALA B CA  1 
ATOM   6303 C  C   . ALA B 1 312 ? 58.42302  -19.72580 -65.66029 1.000 26.30348  ?  312 ALA B C   1 
ATOM   6304 O  O   . ALA B 1 312 ? 59.04983  -18.70742 -65.96638 1.000 30.38741  ?  312 ALA B O   1 
ATOM   6305 C  CB  . ALA B 1 312 ? 56.18761  -19.45327 -64.55694 1.000 24.06200  ?  312 ALA B CB  1 
ATOM   6306 N  N   . MET B 1 313 ? 59.02119  -20.80121 -65.14355 1.000 25.49525  ?  313 MET B N   1 
ATOM   6307 C  CA  . MET B 1 313 ? 60.47456  -20.85007 -65.01308 1.000 26.82658  ?  313 MET B CA  1 
ATOM   6308 C  C   . MET B 1 313 ? 61.14433  -20.73091 -66.37548 1.000 28.78049  ?  313 MET B C   1 
ATOM   6309 O  O   . MET B 1 313 ? 62.09715  -19.96032 -66.55070 1.000 25.78342  ?  313 MET B O   1 
ATOM   6310 C  CB  . MET B 1 313 ? 60.90055  -22.14739 -64.32407 1.000 23.78156  ?  313 MET B CB  1 
ATOM   6311 C  CG  . MET B 1 313 ? 60.48896  -22.26288 -62.86887 1.000 26.53718  ?  313 MET B CG  1 
ATOM   6312 S  SD  . MET B 1 313 ? 60.93752  -23.86571 -62.17301 1.000 33.28510  ?  313 MET B SD  1 
ATOM   6313 C  CE  . MET B 1 313 ? 62.71369  -23.85065 -62.40232 1.000 26.59599  ?  313 MET B CE  1 
ATOM   6314 N  N   . ASP B 1 314 ? 60.64611  -21.48444 -67.35921 1.000 27.03402  ?  314 ASP B N   1 
ATOM   6315 C  CA  . ASP B 1 314 ? 61.23464  -21.43400 -68.69505 1.000 28.10911  ?  314 ASP B CA  1 
ATOM   6316 C  C   . ASP B 1 314 ? 61.09583  -20.04729 -69.31418 1.000 26.39129  ?  314 ASP B C   1 
ATOM   6317 O  O   . ASP B 1 314 ? 62.03510  -19.54245 -69.94014 1.000 25.40342  ?  314 ASP B O   1 
ATOM   6318 C  CB  . ASP B 1 314 ? 60.59396  -22.49072 -69.59445 1.000 37.26123  ?  314 ASP B CB  1 
ATOM   6319 C  CG  . ASP B 1 314 ? 61.07183  -23.89317 -69.27610 1.000 40.17227  ?  314 ASP B CG  1 
ATOM   6320 O  OD1 . ASP B 1 314 ? 61.92545  -24.04244 -68.37548 1.000 34.62025  ?  314 ASP B OD1 1 
ATOM   6321 O  OD2 . ASP B 1 314 ? 60.59536  -24.84579 -69.92860 1.000 50.88440  -1 314 ASP B OD2 1 
ATOM   6322 N  N   . LEU B 1 315 ? 59.93228  -19.41364 -69.14841 1.000 31.07891  ?  315 LEU B N   1 
ATOM   6323 C  CA  . LEU B 1 315 ? 59.71754  -18.09630 -69.74045 1.000 29.85047  ?  315 LEU B CA  1 
ATOM   6324 C  C   . LEU B 1 315 ? 60.49676  -17.01070 -69.00802 1.000 25.92136  ?  315 LEU B C   1 
ATOM   6325 O  O   . LEU B 1 315 ? 60.89184  -16.01447 -69.62271 1.000 21.76330  ?  315 LEU B O   1 
ATOM   6326 C  CB  . LEU B 1 315 ? 58.22562  -17.76352 -69.76033 1.000 24.23418  ?  315 LEU B CB  1 
ATOM   6327 C  CG  . LEU B 1 315 ? 57.35883  -18.66527 -70.64268 1.000 21.13253  ?  315 LEU B CG  1 
ATOM   6328 C  CD1 . LEU B 1 315 ? 55.92661  -18.15849 -70.69501 1.000 25.30814  ?  315 LEU B CD1 1 
ATOM   6329 C  CD2 . LEU B 1 315 ? 57.94465  -18.77693 -72.04203 1.000 31.75010  ?  315 LEU B CD2 1 
ATOM   6330 N  N   . HIS B 1 316 ? 60.71659  -17.17499 -67.70172 1.000 26.24882  ?  316 HIS B N   1 
ATOM   6331 C  CA  . HIS B 1 316 ? 61.55355  -16.23817 -66.96365 1.000 29.53530  ?  316 HIS B CA  1 
ATOM   6332 C  C   . HIS B 1 316 ? 63.01819  -16.38649 -67.34972 1.000 29.57807  ?  316 HIS B C   1 
ATOM   6333 O  O   . HIS B 1 316 ? 63.75747  -15.39631 -67.36360 1.000 27.89524  ?  316 HIS B O   1 
ATOM   6334 C  CB  . HIS B 1 316 ? 61.36450  -16.44883 -65.45992 1.000 38.59009  ?  316 HIS B CB  1 
ATOM   6335 C  CG  . HIS B 1 316 ? 61.95351  -15.36357 -64.61227 1.000 42.75460  ?  316 HIS B CG  1 
ATOM   6336 N  ND1 . HIS B 1 316 ? 61.66177  -14.02948 -64.79990 1.000 37.57430  ?  316 HIS B ND1 1 
ATOM   6337 C  CD2 . HIS B 1 316 ? 62.80743  -15.41741 -63.56252 1.000 31.70379  ?  316 HIS B CD2 1 
ATOM   6338 C  CE1 . HIS B 1 316 ? 62.31582  -13.30796 -63.90706 1.000 32.55742  ?  316 HIS B CE1 1 
ATOM   6339 N  NE2 . HIS B 1 316 ? 63.01828  -14.12602 -63.14417 1.000 27.68881  ?  316 HIS B NE2 1 
ATOM   6340 N  N   . LYS B 1 317 ? 63.45629  -17.61061 -67.65735 1.000 29.16288  ?  317 LYS B N   1 
ATOM   6341 C  CA  . LYS B 1 317 ? 64.81059  -17.79619 -68.17011 1.000 28.56885  ?  317 LYS B CA  1 
ATOM   6342 C  C   . LYS B 1 317 ? 64.95875  -17.20646 -69.56790 1.000 23.69168  ?  317 LYS B C   1 
ATOM   6343 O  O   . LYS B 1 317 ? 65.94663  -16.52117 -69.85744 1.000 20.85471  ?  317 LYS B O   1 
ATOM   6344 C  CB  . LYS B 1 317 ? 65.17591  -19.28093 -68.18757 1.000 29.20647  ?  317 LYS B CB  1 
ATOM   6345 C  CG  . LYS B 1 317 ? 65.22914  -19.95039 -66.82733 1.000 27.26956  ?  317 LYS B CG  1 
ATOM   6346 C  CD  . LYS B 1 317 ? 65.40835  -21.45365 -66.98286 1.000 31.45694  ?  317 LYS B CD  1 
ATOM   6347 C  CE  . LYS B 1 317 ? 65.06955  -22.19877 -65.70204 1.000 27.97520  ?  317 LYS B CE  1 
ATOM   6348 N  NZ  . LYS B 1 317 ? 65.02944  -23.67305 -65.91738 1.000 17.36327  ?  317 LYS B NZ  1 
ATOM   6349 N  N   . LYS B 1 318 ? 63.98790  -17.46596 -70.44851 1.000 27.14962  ?  318 LYS B N   1 
ATOM   6350 C  CA  . LYS B 1 318 ? 64.11103  -17.07336 -71.84889 1.000 31.75567  ?  318 LYS B CA  1 
ATOM   6351 C  C   . LYS B 1 318 ? 63.81738  -15.59453 -72.07276 1.000 26.83474  ?  318 LYS B C   1 
ATOM   6352 O  O   . LYS B 1 318 ? 64.41407  -14.97916 -72.96386 1.000 24.18478  ?  318 LYS B O   1 
ATOM   6353 C  CB  . LYS B 1 318 ? 63.18695  -17.93020 -72.71655 1.000 25.98680  ?  318 LYS B CB  1 
ATOM   6354 C  CG  . LYS B 1 318 ? 63.39477  -17.73948 -74.20913 1.000 26.90887  ?  318 LYS B CG  1 
ATOM   6355 C  CD  . LYS B 1 318 ? 62.66765  -18.79883 -75.01857 1.000 34.18944  ?  318 LYS B CD  1 
ATOM   6356 C  CE  . LYS B 1 318 ? 62.92474  -18.61510 -76.50658 1.000 41.88739  ?  318 LYS B CE  1 
ATOM   6357 N  NZ  . LYS B 1 318 ? 62.32469  -19.70798 -77.31919 1.000 46.20991  ?  318 LYS B NZ  1 
ATOM   6358 N  N   . TYR B 1 319 ? 62.91166  -15.00969 -71.29229 1.000 26.85629  ?  319 TYR B N   1 
ATOM   6359 C  CA  . TYR B 1 319 ? 62.55407  -13.59561 -71.40857 1.000 28.42931  ?  319 TYR B CA  1 
ATOM   6360 C  C   . TYR B 1 319 ? 62.63903  -12.94699 -70.03255 1.000 29.57111  ?  319 TYR B C   1 
ATOM   6361 O  O   . TYR B 1 319 ? 61.62535  -12.51712 -69.46988 1.000 32.01270  ?  319 TYR B O   1 
ATOM   6362 C  CB  . TYR B 1 319 ? 61.15423  -13.42950 -72.00232 1.000 28.78089  ?  319 TYR B CB  1 
ATOM   6363 C  CG  . TYR B 1 319 ? 60.88458  -14.29671 -73.21059 1.000 24.65612  ?  319 TYR B CG  1 
ATOM   6364 C  CD1 . TYR B 1 319 ? 61.27095  -13.89175 -74.48098 1.000 25.79725  ?  319 TYR B CD1 1 
ATOM   6365 C  CD2 . TYR B 1 319 ? 60.23676  -15.51811 -73.08090 1.000 27.43442  ?  319 TYR B CD2 1 
ATOM   6366 C  CE1 . TYR B 1 319 ? 61.02500  -14.68163 -75.58872 1.000 28.66890  ?  319 TYR B CE1 1 
ATOM   6367 C  CE2 . TYR B 1 319 ? 59.98644  -16.31459 -74.18216 1.000 36.68112  ?  319 TYR B CE2 1 
ATOM   6368 C  CZ  . TYR B 1 319 ? 60.38282  -15.89180 -75.43358 1.000 29.24752  ?  319 TYR B CZ  1 
ATOM   6369 O  OH  . TYR B 1 319 ? 60.13594  -16.68232 -76.53251 1.000 24.86036  ?  319 TYR B OH  1 
ATOM   6370 N  N   . PRO B 1 320 ? 63.84345  -12.85776 -69.45864 1.000 28.89741  ?  320 PRO B N   1 
ATOM   6371 C  CA  . PRO B 1 320 ? 63.96381  -12.30066 -68.10254 1.000 38.47429  ?  320 PRO B CA  1 
ATOM   6372 C  C   . PRO B 1 320 ? 63.59423  -10.83179 -68.01224 1.000 41.00978  ?  320 PRO B C   1 
ATOM   6373 O  O   . PRO B 1 320 ? 63.24844  -10.36556 -66.91945 1.000 38.10314  ?  320 PRO B O   1 
ATOM   6374 C  CB  . PRO B 1 320 ? 65.44228  -12.52658 -67.76212 1.000 35.63951  ?  320 PRO B CB  1 
ATOM   6375 C  CG  . PRO B 1 320 ? 66.12443  -12.51149 -69.08574 1.000 23.01994  ?  320 PRO B CG  1 
ATOM   6376 C  CD  . PRO B 1 320 ? 65.16072  -13.14116 -70.05597 1.000 27.97797  ?  320 PRO B CD  1 
ATOM   6377 N  N   . ASP B 1 321 ? 63.64963  -10.09202 -69.11863 1.000 34.72480  ?  321 ASP B N   1 
ATOM   6378 C  CA  . ASP B 1 321 ? 63.36160  -8.66600  -69.09886 1.000 35.17022  ?  321 ASP B CA  1 
ATOM   6379 C  C   . ASP B 1 321 ? 61.87828  -8.35463  -69.23710 1.000 32.46284  ?  321 ASP B C   1 
ATOM   6380 O  O   . ASP B 1 321 ? 61.43908  -7.29103  -68.78506 1.000 37.11682  ?  321 ASP B O   1 
ATOM   6381 C  CB  . ASP B 1 321 ? 64.13512  -7.96078  -70.21850 1.000 41.35847  ?  321 ASP B CB  1 
ATOM   6382 C  CG  . ASP B 1 321 ? 64.25600  -6.46641  -69.99358 1.000 59.27572  ?  321 ASP B CG  1 
ATOM   6383 O  OD1 . ASP B 1 321 ? 63.90991  -5.99889  -68.88852 1.000 58.44356  ?  321 ASP B OD1 1 
ATOM   6384 O  OD2 . ASP B 1 321 ? 64.69971  -5.75923  -70.92376 1.000 60.98745  -1 321 ASP B OD2 1 
ATOM   6385 N  N   . PHE B 1 322 ? 61.10041  -9.24930  -69.84145 1.000 27.58169  ?  322 PHE B N   1 
ATOM   6386 C  CA  . PHE B 1 322 ? 59.67693  -9.03132  -70.07094 1.000 28.81155  ?  322 PHE B CA  1 
ATOM   6387 C  C   . PHE B 1 322 ? 58.78418  -9.88425  -69.18406 1.000 29.12551  ?  322 PHE B C   1 
ATOM   6388 O  O   . PHE B 1 322 ? 57.72002  -9.42406  -68.76320 1.000 21.94840  ?  322 PHE B O   1 
ATOM   6389 C  CB  . PHE B 1 322 ? 59.34195  -9.30110  -71.54279 1.000 23.07622  ?  322 PHE B CB  1 
ATOM   6390 C  CG  . PHE B 1 322 ? 57.99283  -8.79624  -71.96188 1.000 20.53285  ?  322 PHE B CG  1 
ATOM   6391 C  CD1 . PHE B 1 322 ? 57.69132  -7.44654  -71.88882 1.000 23.56754  ?  322 PHE B CD1 1 
ATOM   6392 C  CD2 . PHE B 1 322 ? 57.03305  -9.66692  -72.44699 1.000 22.40823  ?  322 PHE B CD2 1 
ATOM   6393 C  CE1 . PHE B 1 322 ? 56.45420  -6.97690  -72.27817 1.000 21.76052  ?  322 PHE B CE1 1 
ATOM   6394 C  CE2 . PHE B 1 322 ? 55.79431  -9.20334  -72.83925 1.000 26.91839  ?  322 PHE B CE2 1 
ATOM   6395 C  CZ  . PHE B 1 322 ? 55.50441  -7.85579  -72.75482 1.000 26.39944  ?  322 PHE B CZ  1 
ATOM   6396 N  N   . PHE B 1 323 ? 59.19489  -11.11453 -68.88725 1.000 36.57071  ?  323 PHE B N   1 
ATOM   6397 C  CA  . PHE B 1 323 ? 58.43914  -12.01237 -68.02434 1.000 30.55684  ?  323 PHE B CA  1 
ATOM   6398 C  C   . PHE B 1 323 ? 58.93389  -11.86763 -66.59002 1.000 28.49784  ?  323 PHE B C   1 
ATOM   6399 O  O   . PHE B 1 323 ? 60.13798  -11.95986 -66.32970 1.000 28.97136  ?  323 PHE B O   1 
ATOM   6400 C  CB  . PHE B 1 323 ? 58.58824  -13.45707 -68.50489 1.000 27.09659  ?  323 PHE B CB  1 
ATOM   6401 C  CG  . PHE B 1 323 ? 57.69596  -14.43482 -67.79524 1.000 27.34116  ?  323 PHE B CG  1 
ATOM   6402 C  CD1 . PHE B 1 323 ? 58.10952  -15.04795 -66.62357 1.000 25.50067  ?  323 PHE B CD1 1 
ATOM   6403 C  CD2 . PHE B 1 323 ? 56.44991  -14.75450 -68.30974 1.000 23.10488  ?  323 PHE B CD2 1 
ATOM   6404 C  CE1 . PHE B 1 323 ? 57.29377  -15.95140 -65.97238 1.000 23.96473  ?  323 PHE B CE1 1 
ATOM   6405 C  CE2 . PHE B 1 323 ? 55.62978  -15.65887 -67.66318 1.000 18.07167  ?  323 PHE B CE2 1 
ATOM   6406 C  CZ  . PHE B 1 323 ? 56.05384  -16.25777 -66.49309 1.000 19.93761  ?  323 PHE B CZ  1 
ATOM   6407 N  N   . LEU B 1 324 ? 58.00235  -11.64689 -65.66202 1.000 22.76516  ?  324 LEU B N   1 
ATOM   6408 C  CA  . LEU B 1 324 ? 58.34286  -11.31969 -64.28087 1.000 29.62087  ?  324 LEU B CA  1 
ATOM   6409 C  C   . LEU B 1 324 ? 58.29988  -12.53570 -63.36100 1.000 40.75003  ?  324 LEU B C   1 
ATOM   6410 O  O   . LEU B 1 324 ? 59.30726  -12.87956 -62.73569 1.000 39.64168  ?  324 LEU B O   1 
ATOM   6411 C  CB  . LEU B 1 324 ? 57.39848  -10.22909 -63.76130 1.000 29.58687  ?  324 LEU B CB  1 
ATOM   6412 C  CG  . LEU B 1 324 ? 57.38674  -8.94011  -64.57924 1.000 31.50751  ?  324 LEU B CG  1 
ATOM   6413 C  CD1 . LEU B 1 324 ? 56.50603  -7.89379  -63.91472 1.000 26.02639  ?  324 LEU B CD1 1 
ATOM   6414 C  CD2 . LEU B 1 324 ? 58.80586  -8.43000  -64.76388 1.000 27.82747  ?  324 LEU B CD2 1 
ATOM   6415 N  N   . GLY B 1 325 ? 57.14830  -13.19549 -63.26545 1.000 33.45678  ?  325 GLY B N   1 
ATOM   6416 C  CA  . GLY B 1 325 ? 57.00778  -14.30659 -62.34575 1.000 23.39368  ?  325 GLY B CA  1 
ATOM   6417 C  C   . GLY B 1 325 ? 55.68278  -15.03183 -62.44749 1.000 27.62265  ?  325 GLY B C   1 
ATOM   6418 O  O   . GLY B 1 325 ? 55.13511  -15.19126 -63.54263 1.000 33.20812  ?  325 GLY B O   1 
ATOM   6419 N  N   . TYR B 1 326 ? 55.15556  -15.47378 -61.30732 1.000 28.84538  ?  326 TYR B N   1 
ATOM   6420 C  CA  . TYR B 1 326 ? 53.94706  -16.28291 -61.27547 1.000 29.27577  ?  326 TYR B CA  1 
ATOM   6421 C  C   . TYR B 1 326 ? 53.03086  -15.78735 -60.16447 1.000 26.40908  ?  326 TYR B C   1 
ATOM   6422 O  O   . TYR B 1 326 ? 53.47148  -15.15799 -59.19955 1.000 28.54700  ?  326 TYR B O   1 
ATOM   6423 C  CB  . TYR B 1 326 ? 54.28086  -17.76897 -61.08189 1.000 27.00476  ?  326 TYR B CB  1 
ATOM   6424 C  CG  . TYR B 1 326 ? 53.09154  -18.69511 -61.18794 1.000 22.97425  ?  326 TYR B CG  1 
ATOM   6425 C  CD1 . TYR B 1 326 ? 52.56243  -19.03892 -62.42524 1.000 20.98776  ?  326 TYR B CD1 1 
ATOM   6426 C  CD2 . TYR B 1 326 ? 52.50432  -19.23427 -60.05051 1.000 20.09128  ?  326 TYR B CD2 1 
ATOM   6427 C  CE1 . TYR B 1 326 ? 51.47697  -19.89009 -62.52646 1.000 20.81365  ?  326 TYR B CE1 1 
ATOM   6428 C  CE2 . TYR B 1 326 ? 51.42030  -20.08474 -60.14099 1.000 20.82492  ?  326 TYR B CE2 1 
ATOM   6429 C  CZ  . TYR B 1 326 ? 50.91046  -20.40991 -61.38062 1.000 21.70746  ?  326 TYR B CZ  1 
ATOM   6430 O  OH  . TYR B 1 326 ? 49.82997  -21.25717 -61.47056 1.000 19.49418  ?  326 TYR B OH  1 
ATOM   6431 N  N   . ASP B 1 327 ? 51.74045  -16.07794 -60.31782 1.000 19.71016  ?  327 ASP B N   1 
ATOM   6432 C  CA  . ASP B 1 327 ? 50.72748  -15.64658 -59.36592 1.000 19.63982  ?  327 ASP B CA  1 
ATOM   6433 C  C   . ASP B 1 327 ? 49.52781  -16.57580 -59.47891 1.000 18.71467  ?  327 ASP B C   1 
ATOM   6434 O  O   . ASP B 1 327 ? 49.19511  -17.03305 -60.57356 1.000 17.98602  ?  327 ASP B O   1 
ATOM   6435 C  CB  . ASP B 1 327 ? 50.30940  -14.19370 -59.62970 1.000 28.18588  ?  327 ASP B CB  1 
ATOM   6436 C  CG  . ASP B 1 327 ? 49.24713  -13.69771 -58.66236 1.000 29.46277  ?  327 ASP B CG  1 
ATOM   6437 O  OD1 . ASP B 1 327 ? 49.11104  -14.27113 -57.56320 1.000 24.39342  ?  327 ASP B OD1 1 
ATOM   6438 O  OD2 . ASP B 1 327 ? 48.54488  -12.72381 -59.00480 1.000 30.25299  -1 327 ASP B OD2 1 
ATOM   6439 N  N   . LEU B 1 328 ? 48.89002  -16.85367 -58.34640 1.000 17.32545  ?  328 LEU B N   1 
ATOM   6440 C  CA  . LEU B 1 328 ? 47.65949  -17.63153 -58.30830 1.000 19.73200  ?  328 LEU B CA  1 
ATOM   6441 C  C   . LEU B 1 328 ? 46.49044  -16.68581 -58.06151 1.000 20.85765  ?  328 LEU B C   1 
ATOM   6442 O  O   . LEU B 1 328 ? 46.43322  -16.01977 -57.02191 1.000 22.32360  ?  328 LEU B O   1 
ATOM   6443 C  CB  . LEU B 1 328 ? 47.73061  -18.71091 -57.22882 1.000 24.85292  ?  328 LEU B CB  1 
ATOM   6444 C  CG  . LEU B 1 328 ? 48.68197  -19.86820 -57.54295 1.000 25.60117  ?  328 LEU B CG  1 
ATOM   6445 C  CD1 . LEU B 1 328 ? 48.97758  -20.68231 -56.29673 1.000 22.09873  ?  328 LEU B CD1 1 
ATOM   6446 C  CD2 . LEU B 1 328 ? 48.10097  -20.75372 -58.63580 1.000 19.12216  ?  328 LEU B CD2 1 
ATOM   6447 N  N   . VAL B 1 329 ? 45.56213  -16.63494 -59.01591 1.000 20.65280  ?  329 VAL B N   1 
ATOM   6448 C  CA  . VAL B 1 329 ? 44.42961  -15.71750 -58.96692 1.000 16.53662  ?  329 VAL B CA  1 
ATOM   6449 C  C   . VAL B 1 329 ? 43.13341  -16.51516 -58.90721 1.000 18.72352  ?  329 VAL B C   1 
ATOM   6450 O  O   . VAL B 1 329 ? 43.14868  -17.75088 -58.91700 1.000 23.08603  ?  329 VAL B O   1 
ATOM   6451 C  CB  . VAL B 1 329 ? 44.43603  -14.76039 -60.17230 1.000 14.12754  ?  329 VAL B CB  1 
ATOM   6452 C  CG1 . VAL B 1 329 ? 45.75791  -14.01294 -60.24716 1.000 16.99417  ?  329 VAL B CG1 1 
ATOM   6453 C  CG2 . VAL B 1 329 ? 44.17801  -15.52683 -61.45821 1.000 19.04549  ?  329 VAL B CG2 1 
ATOM   6454 N  N   . GLY B 1 330 ? 42.00806  -15.81549 -58.85392 1.000 14.01247  ?  330 GLY B N   1 
ATOM   6455 C  CA  . GLY B 1 330 ? 40.72211  -16.42634 -58.60147 1.000 12.40712  ?  330 GLY B CA  1 
ATOM   6456 C  C   . GLY B 1 330 ? 40.26265  -16.19071 -57.17200 1.000 16.05562  ?  330 GLY B C   1 
ATOM   6457 O  O   . GLY B 1 330 ? 41.03937  -15.82240 -56.28701 1.000 20.68308  ?  330 GLY B O   1 
ATOM   6458 N  N   . GLN B 1 331 ? 38.96563  -16.40139 -56.94646 1.000 15.39939  ?  331 GLN B N   1 
ATOM   6459 C  CA  . GLN B 1 331 ? 38.39273  -16.14581 -55.63010 1.000 17.64139  ?  331 GLN B CA  1 
ATOM   6460 C  C   . GLN B 1 331 ? 39.09438  -16.99456 -54.57742 1.000 18.84952  ?  331 GLN B C   1 
ATOM   6461 O  O   . GLN B 1 331 ? 39.18170  -18.21882 -54.70314 1.000 17.82814  ?  331 GLN B O   1 
ATOM   6462 C  CB  . GLN B 1 331 ? 36.89187  -16.43280 -55.63425 1.000 16.65604  ?  331 GLN B CB  1 
ATOM   6463 C  CG  . GLN B 1 331 ? 36.16965  -15.91637 -54.39893 1.000 17.26707  ?  331 GLN B CG  1 
ATOM   6464 C  CD  . GLN B 1 331 ? 34.70596  -16.31081 -54.36677 1.000 20.41026  ?  331 GLN B CD  1 
ATOM   6465 O  OE1 . GLN B 1 331 ? 34.15158  -16.76400 -55.36747 1.000 32.05264  ?  331 GLN B OE1 1 
ATOM   6466 N  NE2 . GLN B 1 331 ? 34.07255  -16.14318 -53.21143 1.000 14.65480  ?  331 GLN B NE2 1 
ATOM   6467 N  N   . GLU B 1 332 ? 39.59788  -16.33487 -53.53602 1.000 21.64360  ?  332 GLU B N   1 
ATOM   6468 C  CA  . GLU B 1 332 ? 40.48363  -16.98567 -52.57955 1.000 20.28631  ?  332 GLU B CA  1 
ATOM   6469 C  C   . GLU B 1 332 ? 39.74078  -17.64782 -51.42670 1.000 20.24033  ?  332 GLU B C   1 
ATOM   6470 O  O   . GLU B 1 332 ? 40.26808  -18.59269 -50.82733 1.000 22.01201  ?  332 GLU B O   1 
ATOM   6471 C  CB  . GLU B 1 332 ? 41.49016  -15.96859 -52.03124 1.000 21.37022  ?  332 GLU B CB  1 
ATOM   6472 C  CG  . GLU B 1 332 ? 42.75158  -16.58178 -51.44545 1.000 23.79579  ?  332 GLU B CG  1 
ATOM   6473 C  CD  . GLU B 1 332 ? 43.78598  -15.53732 -51.06488 1.000 25.27951  ?  332 GLU B CD  1 
ATOM   6474 O  OE1 . GLU B 1 332 ? 43.53452  -14.33526 -51.29735 1.000 21.59873  ?  332 GLU B OE1 1 
ATOM   6475 O  OE2 . GLU B 1 332 ? 44.85182  -15.91922 -50.53541 1.000 25.21784  -1 332 GLU B OE2 1 
ATOM   6476 N  N   . ASP B 1 333 ? 38.53654  -17.17635 -51.09666 1.000 15.92364  ?  333 ASP B N   1 
ATOM   6477 C  CA  . ASP B 1 333 ? 37.79869  -17.75958 -49.97639 1.000 16.53021  ?  333 ASP B CA  1 
ATOM   6478 C  C   . ASP B 1 333 ? 37.43358  -19.22587 -50.18684 1.000 17.17689  ?  333 ASP B C   1 
ATOM   6479 O  O   . ASP B 1 333 ? 37.74757  -20.04476 -49.30539 1.000 18.91249  ?  333 ASP B O   1 
ATOM   6480 C  CB  . ASP B 1 333 ? 36.55351  -16.91524 -49.67740 1.000 18.99745  ?  333 ASP B CB  1 
ATOM   6481 C  CG  . ASP B 1 333 ? 36.81105  -15.84170 -48.64289 1.000 18.19403  ?  333 ASP B CG  1 
ATOM   6482 O  OD1 . ASP B 1 333 ? 37.79711  -15.96998 -47.88815 1.000 18.35094  ?  333 ASP B OD1 1 
ATOM   6483 O  OD2 . ASP B 1 333 ? 36.02144  -14.87652 -48.57730 1.000 17.80347  -1 333 ASP B OD2 1 
ATOM   6484 N  N   . PRO B 1 334 ? 36.79450  -19.63464 -51.28535 1.000 19.55076  ?  334 PRO B N   1 
ATOM   6485 C  CA  . PRO B 1 334 ? 36.34375  -21.03277 -51.40442 1.000 17.85399  ?  334 PRO B CA  1 
ATOM   6486 C  C   . PRO B 1 334 ? 37.29297  -21.96459 -52.15097 1.000 13.32466  ?  334 PRO B C   1 
ATOM   6487 O  O   . PRO B 1 334 ? 36.92319  -23.12403 -52.36539 1.000 13.02757  ?  334 PRO B O   1 
ATOM   6488 C  CB  . PRO B 1 334 ? 35.03899  -20.87062 -52.18971 1.000 28.20335  ?  334 PRO B CB  1 
ATOM   6489 C  CG  . PRO B 1 334 ? 35.35134  -19.76462 -53.14256 1.000 21.37468  ?  334 PRO B CG  1 
ATOM   6490 C  CD  . PRO B 1 334 ? 36.32695  -18.83848 -52.43723 1.000 21.17601  ?  334 PRO B CD  1 
ATOM   6491 N  N   . ASN B 1 335 ? 38.47630  -21.50445 -52.54607 1.000 16.99837  ?  335 ASN B N   1 
ATOM   6492 C  CA  . ASN B 1 335 ? 39.39129  -22.29263 -53.35622 1.000 15.96431  ?  335 ASN B CA  1 
ATOM   6493 C  C   . ASN B 1 335 ? 40.60492  -22.72332 -52.53225 1.000 16.36652  ?  335 ASN B C   1 
ATOM   6494 O  O   . ASN B 1 335 ? 40.67520  -22.50114 -51.31736 1.000 15.39629  ?  335 ASN B O   1 
ATOM   6495 C  CB  . ASN B 1 335 ? 39.79669  -21.50487 -54.60403 1.000 15.33495  ?  335 ASN B CB  1 
ATOM   6496 C  CG  . ASN B 1 335 ? 38.66403  -21.38015 -55.60493 1.000 15.57600  ?  335 ASN B CG  1 
ATOM   6497 O  OD1 . ASN B 1 335 ? 37.71687  -22.16619 -55.58756 1.000 17.13420  ?  335 ASN B OD1 1 
ATOM   6498 N  ND2 . ASN B 1 335 ? 38.75875  -20.39422 -56.48786 1.000 18.79632  ?  335 ASN B ND2 1 
ATOM   6499 N  N   . PHE B 1 336 ? 41.56547  -23.35041 -53.20730 1.000 21.72361  ?  336 PHE B N   1 
ATOM   6500 C  CA  . PHE B 1 336 ? 42.71342  -23.94290 -52.53574 1.000 23.83003  ?  336 PHE B CA  1 
ATOM   6501 C  C   . PHE B 1 336 ? 43.65462  -22.87648 -51.98411 1.000 21.23532  ?  336 PHE B C   1 
ATOM   6502 O  O   . PHE B 1 336 ? 43.78814  -21.78080 -52.53568 1.000 22.32501  ?  336 PHE B O   1 
ATOM   6503 C  CB  . PHE B 1 336 ? 43.47517  -24.85734 -53.49483 1.000 21.61695  ?  336 PHE B CB  1 
ATOM   6504 C  CG  . PHE B 1 336 ? 42.65659  -26.00322 -54.01805 1.000 24.69298  ?  336 PHE B CG  1 
ATOM   6505 C  CD1 . PHE B 1 336 ? 42.27166  -27.03603 -53.17896 1.000 20.22838  ?  336 PHE B CD1 1 
ATOM   6506 C  CD2 . PHE B 1 336 ? 42.27768  -26.05131 -55.34965 1.000 24.63726  ?  336 PHE B CD2 1 
ATOM   6507 C  CE1 . PHE B 1 336 ? 41.52033  -28.09230 -53.65659 1.000 15.46442  ?  336 PHE B CE1 1 
ATOM   6508 C  CE2 . PHE B 1 336 ? 41.52668  -27.10520 -55.83382 1.000 22.27251  ?  336 PHE B CE2 1 
ATOM   6509 C  CZ  . PHE B 1 336 ? 41.14765  -28.12708 -54.98592 1.000 19.41907  ?  336 PHE B CZ  1 
ATOM   6510 N  N   . SER B 1 337 ? 44.31616  -23.21855 -50.88135 1.000 17.35052  ?  337 SER B N   1 
ATOM   6511 C  CA  . SER B 1 337 ? 45.26900  -22.33425 -50.23273 1.000 19.22359  ?  337 SER B CA  1 
ATOM   6512 C  C   . SER B 1 337 ? 46.63708  -22.42932 -50.90602 1.000 18.70033  ?  337 SER B C   1 
ATOM   6513 O  O   . SER B 1 337 ? 46.89650  -23.30668 -51.73381 1.000 20.97781  ?  337 SER B O   1 
ATOM   6514 C  CB  . SER B 1 337 ? 45.38324  -22.67519 -48.74786 1.000 23.69258  ?  337 SER B CB  1 
ATOM   6515 O  OG  . SER B 1 337 ? 45.78122  -24.02278 -48.56489 1.000 19.95239  ?  337 SER B OG  1 
ATOM   6516 N  N   . LEU B 1 338 ? 47.52220  -21.49763 -50.54109 1.000 22.51007  ?  338 LEU B N   1 
ATOM   6517 C  CA  . LEU B 1 338 ? 48.88760  -21.53714 -51.05623 1.000 27.82632  ?  338 LEU B CA  1 
ATOM   6518 C  C   . LEU B 1 338 ? 49.61989  -22.78135 -50.57282 1.000 28.94633  ?  338 LEU B C   1 
ATOM   6519 O  O   . LEU B 1 338 ? 50.41567  -23.37050 -51.31397 1.000 29.13057  ?  338 LEU B O   1 
ATOM   6520 C  CB  . LEU B 1 338 ? 49.64900  -20.27531 -50.64705 1.000 27.17567  ?  338 LEU B CB  1 
ATOM   6521 C  CG  . LEU B 1 338 ? 49.38135  -19.01051 -51.46422 1.000 22.33818  ?  338 LEU B CG  1 
ATOM   6522 C  CD1 . LEU B 1 338 ? 50.31840  -17.89073 -51.04214 1.000 18.73845  ?  338 LEU B CD1 1 
ATOM   6523 C  CD2 . LEU B 1 338 ? 49.52327  -19.29810 -52.94870 1.000 23.94594  ?  338 LEU B CD2 1 
ATOM   6524 N  N   . LEU B 1 339 ? 49.36872  -23.19150 -49.32702 1.000 24.83191  ?  339 LEU B N   1 
ATOM   6525 C  CA  . LEU B 1 339 ? 49.99022  -24.40345 -48.80464 1.000 22.89394  ?  339 LEU B CA  1 
ATOM   6526 C  C   . LEU B 1 339 ? 49.55359  -25.63626 -49.58445 1.000 22.53191  ?  339 LEU B C   1 
ATOM   6527 O  O   . LEU B 1 339 ? 50.34539  -26.56892 -49.76609 1.000 19.48900  ?  339 LEU B O   1 
ATOM   6528 C  CB  . LEU B 1 339 ? 49.65316  -24.56495 -47.32309 1.000 21.04747  ?  339 LEU B CB  1 
ATOM   6529 C  CG  . LEU B 1 339 ? 50.28699  -25.75851 -46.61143 1.000 14.03011  ?  339 LEU B CG  1 
ATOM   6530 C  CD1 . LEU B 1 339 ? 51.80029  -25.61900 -46.59346 1.000 17.67060  ?  339 LEU B CD1 1 
ATOM   6531 C  CD2 . LEU B 1 339 ? 49.73431  -25.89328 -45.20319 1.000 17.80835  ?  339 LEU B CD2 1 
ATOM   6532 N  N   . HIS B 1 340 ? 48.30185  -25.65635 -50.05265 1.000 22.30132  ?  340 HIS B N   1 
ATOM   6533 C  CA  . HIS B 1 340 ? 47.80222  -26.79318 -50.82033 1.000 22.56653  ?  340 HIS B CA  1 
ATOM   6534 C  C   . HIS B 1 340 ? 48.60189  -27.00562 -52.10049 1.000 25.89390  ?  340 HIS B C   1 
ATOM   6535 O  O   . HIS B 1 340 ? 48.69131  -28.13460 -52.59766 1.000 23.25663  ?  340 HIS B O   1 
ATOM   6536 C  CB  . HIS B 1 340 ? 46.31941  -26.58733 -51.13598 1.000 18.92616  ?  340 HIS B CB  1 
ATOM   6537 C  CG  . HIS B 1 340 ? 45.77048  -27.55414 -52.13749 1.000 16.90546  ?  340 HIS B CG  1 
ATOM   6538 N  ND1 . HIS B 1 340 ? 45.72464  -27.27995 -53.48742 1.000 18.37794  ?  340 HIS B ND1 1 
ATOM   6539 C  CD2 . HIS B 1 340 ? 45.23962  -28.79018 -51.98657 1.000 21.93992  ?  340 HIS B CD2 1 
ATOM   6540 C  CE1 . HIS B 1 340 ? 45.19201  -28.30635 -54.12568 1.000 17.70430  ?  340 HIS B CE1 1 
ATOM   6541 N  NE2 . HIS B 1 340 ? 44.88858  -29.23596 -53.23788 1.000 27.29669  ?  340 HIS B NE2 1 
ATOM   6542 N  N   . TYR B 1 341 ? 49.19599  -25.94265 -52.63890 1.000 24.12847  ?  341 TYR B N   1 
ATOM   6543 C  CA  . TYR B 1 341 ? 50.03075  -26.01447 -53.82918 1.000 22.22537  ?  341 TYR B CA  1 
ATOM   6544 C  C   . TYR B 1 341 ? 51.51573  -26.06841 -53.49741 1.000 30.62237  ?  341 TYR B C   1 
ATOM   6545 O  O   . TYR B 1 341 ? 52.34562  -25.90268 -54.40034 1.000 32.96317  ?  341 TYR B O   1 
ATOM   6546 C  CB  . TYR B 1 341 ? 49.75016  -24.81759 -54.73855 1.000 16.39943  ?  341 TYR B CB  1 
ATOM   6547 C  CG  . TYR B 1 341 ? 48.41826  -24.87075 -55.44847 1.000 16.76083  ?  341 TYR B CG  1 
ATOM   6548 C  CD1 . TYR B 1 341 ? 48.01002  -26.01575 -56.11795 1.000 18.70318  ?  341 TYR B CD1 1 
ATOM   6549 C  CD2 . TYR B 1 341 ? 47.56855  -23.77421 -55.44887 1.000 22.02797  ?  341 TYR B CD2 1 
ATOM   6550 C  CE1 . TYR B 1 341 ? 46.79326  -26.06496 -56.77118 1.000 16.96929  ?  341 TYR B CE1 1 
ATOM   6551 C  CE2 . TYR B 1 341 ? 46.35208  -23.81338 -56.09820 1.000 21.99287  ?  341 TYR B CE2 1 
ATOM   6552 C  CZ  . TYR B 1 341 ? 45.96942  -24.96023 -56.75799 1.000 17.57063  ?  341 TYR B CZ  1 
ATOM   6553 O  OH  . TYR B 1 341 ? 44.75684  -24.99920 -57.40448 1.000 19.94832  ?  341 TYR B OH  1 
ATOM   6554 N  N   . LEU B 1 342 ? 51.86170  -26.32060 -52.22912 1.000 27.36925  ?  342 LEU B N   1 
ATOM   6555 C  CA  . LEU B 1 342 ? 53.22809  -26.11589 -51.75279 1.000 23.91240  ?  342 LEU B CA  1 
ATOM   6556 C  C   . LEU B 1 342 ? 54.25018  -26.80980 -52.64170 1.000 23.30940  ?  342 LEU B C   1 
ATOM   6557 O  O   . LEU B 1 342 ? 55.25409  -26.20358 -53.03221 1.000 25.77250  ?  342 LEU B O   1 
ATOM   6558 C  CB  . LEU B 1 342 ? 53.36439  -26.60368 -50.31053 1.000 19.64072  ?  342 LEU B CB  1 
ATOM   6559 C  CG  . LEU B 1 342 ? 54.79647  -26.54477 -49.77343 1.000 15.37342  ?  342 LEU B CG  1 
ATOM   6560 C  CD1 . LEU B 1 342 ? 55.34257  -25.12934 -49.86855 1.000 15.81795  ?  342 LEU B CD1 1 
ATOM   6561 C  CD2 . LEU B 1 342 ? 54.86725  -27.05485 -48.34394 1.000 23.76800  ?  342 LEU B CD2 1 
ATOM   6562 N  N   . ASP B 1 343 ? 54.00558  -28.08088 -52.97631 1.000 27.23664  ?  343 ASP B N   1 
ATOM   6563 C  CA  . ASP B 1 343 ? 54.90092  -28.81008 -53.87000 1.000 30.99726  ?  343 ASP B CA  1 
ATOM   6564 C  C   . ASP B 1 343 ? 55.24193  -27.97268 -55.09644 1.000 31.84956  ?  343 ASP B C   1 
ATOM   6565 O  O   . ASP B 1 343 ? 56.40089  -27.59141 -55.30721 1.000 30.97439  ?  343 ASP B O   1 
ATOM   6566 C  CB  . ASP B 1 343 ? 54.26435  -30.13916 -54.28868 1.000 28.40869  ?  343 ASP B CB  1 
ATOM   6567 C  CG  . ASP B 1 343 ? 54.22973  -31.15628 -53.16401 1.000 38.00492  ?  343 ASP B CG  1 
ATOM   6568 O  OD1 . ASP B 1 343 ? 54.48397  -30.77724 -52.00161 1.000 33.83575  ?  343 ASP B OD1 1 
ATOM   6569 O  OD2 . ASP B 1 343 ? 53.95377  -32.34154 -53.44744 1.000 49.76402  -1 343 ASP B OD2 1 
ATOM   6570 N  N   . ALA B 1 344 ? 54.21881  -27.62012 -55.88059 1.000 29.10431  ?  344 ALA B N   1 
ATOM   6571 C  CA  . ALA B 1 344 ? 54.44774  -26.84497 -57.09354 1.000 25.35184  ?  344 ALA B CA  1 
ATOM   6572 C  C   . ALA B 1 344 ? 55.13626  -25.52223 -56.79194 1.000 27.93599  ?  344 ALA B C   1 
ATOM   6573 O  O   . ALA B 1 344 ? 55.95942  -25.05630 -57.58810 1.000 32.00295  ?  344 ALA B O   1 
ATOM   6574 C  CB  . ALA B 1 344 ? 53.12154  -26.59946 -57.81323 1.000 24.36511  ?  344 ALA B CB  1 
ATOM   6575 N  N   . LEU B 1 345 ? 54.82795  -24.91012 -55.64681 1.000 26.85248  ?  345 LEU B N   1 
ATOM   6576 C  CA  . LEU B 1 345 ? 55.42483  -23.62604 -55.31449 1.000 31.24877  ?  345 LEU B CA  1 
ATOM   6577 C  C   . LEU B 1 345 ? 56.87300  -23.75216 -54.86332 1.000 31.29286  ?  345 LEU B C   1 
ATOM   6578 O  O   . LEU B 1 345 ? 57.62438  -22.77708 -54.97047 1.000 33.32190  ?  345 LEU B O   1 
ATOM   6579 C  CB  . LEU B 1 345 ? 54.59058  -22.92664 -54.23956 1.000 31.89373  ?  345 LEU B CB  1 
ATOM   6580 C  CG  . LEU B 1 345 ? 53.16649  -22.58529 -54.68942 1.000 30.89030  ?  345 LEU B CG  1 
ATOM   6581 C  CD1 . LEU B 1 345 ? 52.36667  -21.94285 -53.56699 1.000 26.63607  ?  345 LEU B CD1 1 
ATOM   6582 C  CD2 . LEU B 1 345 ? 53.19645  -21.68499 -55.91890 1.000 27.09689  ?  345 LEU B CD2 1 
ATOM   6583 N  N   . LEU B 1 346 ? 57.28446  -24.91979 -54.37111 1.000 29.08050  ?  346 LEU B N   1 
ATOM   6584 C  CA  . LEU B 1 346 ? 58.66601  -25.12896 -53.95899 1.000 24.05761  ?  346 LEU B CA  1 
ATOM   6585 C  C   . LEU B 1 346 ? 59.52370  -25.73505 -55.05834 1.000 29.99303  ?  346 LEU B C   1 
ATOM   6586 O  O   . LEU B 1 346 ? 60.73501  -25.88238 -54.86672 1.000 28.77402  ?  346 LEU B O   1 
ATOM   6587 C  CB  . LEU B 1 346 ? 58.72435  -26.02030 -52.71560 1.000 20.23784  ?  346 LEU B CB  1 
ATOM   6588 C  CG  . LEU B 1 346 ? 58.71438  -25.29946 -51.36851 1.000 19.09335  ?  346 LEU B CG  1 
ATOM   6589 C  CD1 . LEU B 1 346 ? 58.88724  -26.29469 -50.23384 1.000 25.64552  ?  346 LEU B CD1 1 
ATOM   6590 C  CD2 . LEU B 1 346 ? 59.79962  -24.23611 -51.32405 1.000 17.33632  ?  346 LEU B CD2 1 
ATOM   6591 N  N   . TYR B 1 347 ? 58.92576  -26.08423 -56.19627 1.000 30.66748  ?  347 TYR B N   1 
ATOM   6592 C  CA  . TYR B 1 347 ? 59.68600  -26.70954 -57.27437 1.000 32.86783  ?  347 TYR B CA  1 
ATOM   6593 C  C   . TYR B 1 347 ? 60.86444  -25.87156 -57.76295 1.000 33.51039  ?  347 TYR B C   1 
ATOM   6594 O  O   . TYR B 1 347 ? 61.94402  -26.45178 -57.97369 1.000 33.17269  ?  347 TYR B O   1 
ATOM   6595 C  CB  . TYR B 1 347 ? 58.74104  -27.05409 -58.43327 1.000 33.94264  ?  347 TYR B CB  1 
ATOM   6596 C  CG  . TYR B 1 347 ? 59.43134  -27.69731 -59.61229 1.000 33.57873  ?  347 TYR B CG  1 
ATOM   6597 C  CD1 . TYR B 1 347 ? 59.77733  -29.04135 -59.58950 1.000 30.73739  ?  347 TYR B CD1 1 
ATOM   6598 C  CD2 . TYR B 1 347 ? 59.73535  -26.96105 -60.74939 1.000 36.37532  ?  347 TYR B CD2 1 
ATOM   6599 C  CE1 . TYR B 1 347 ? 60.40953  -29.63373 -60.66514 1.000 35.28087  ?  347 TYR B CE1 1 
ATOM   6600 C  CE2 . TYR B 1 347 ? 60.36691  -27.54415 -61.82940 1.000 37.22998  ?  347 TYR B CE2 1 
ATOM   6601 C  CZ  . TYR B 1 347 ? 60.70151  -28.88037 -61.78244 1.000 34.71979  ?  347 TYR B CZ  1 
ATOM   6602 O  OH  . TYR B 1 347 ? 61.33023  -29.46407 -62.85765 1.000 32.46157  ?  347 TYR B OH  1 
ATOM   6603 N  N   . PRO B 1 348 ? 60.74572  -24.55419 -57.98459 1.000 34.98166  ?  348 PRO B N   1 
ATOM   6604 C  CA  . PRO B 1 348 ? 61.93396  -23.79975 -58.42215 1.000 32.22107  ?  348 PRO B CA  1 
ATOM   6605 C  C   . PRO B 1 348 ? 63.09675  -23.87038 -57.44647 1.000 30.98318  ?  348 PRO B C   1 
ATOM   6606 O  O   . PRO B 1 348 ? 64.25175  -23.96410 -57.87731 1.000 31.88323  ?  348 PRO B O   1 
ATOM   6607 C  CB  . PRO B 1 348 ? 61.40195  -22.36662 -58.56806 1.000 27.66582  ?  348 PRO B CB  1 
ATOM   6608 C  CG  . PRO B 1 348 ? 59.94712  -22.52743 -58.80363 1.000 27.62286  ?  348 PRO B CG  1 
ATOM   6609 C  CD  . PRO B 1 348 ? 59.54188  -23.70147 -57.97080 1.000 30.60365  ?  348 PRO B CD  1 
ATOM   6610 N  N   . SER B 1 349 ? 62.82591  -23.84734 -56.14003 1.000 31.86495  ?  349 SER B N   1 
ATOM   6611 C  CA  . SER B 1 349 ? 63.89469  -23.75187 -55.15217 1.000 33.54125  ?  349 SER B CA  1 
ATOM   6612 C  C   . SER B 1 349 ? 64.60226  -25.07642 -54.89326 1.000 33.48169  ?  349 SER B C   1 
ATOM   6613 O  O   . SER B 1 349 ? 65.73923  -25.06752 -54.40932 1.000 32.98435  ?  349 SER B O   1 
ATOM   6614 C  CB  . SER B 1 349 ? 63.34271  -23.20721 -53.83347 1.000 32.67665  ?  349 SER B CB  1 
ATOM   6615 O  OG  . SER B 1 349 ? 62.38686  -24.09372 -53.27980 1.000 28.68516  ?  349 SER B OG  1 
ATOM   6616 N  N   . ILE B 1 350 ? 63.96552  -26.21291 -55.19689 1.000 29.46007  ?  350 ILE B N   1 
ATOM   6617 C  CA  . ILE B 1 350 ? 64.56522  -27.51200 -54.90738 1.000 28.06447  ?  350 ILE B CA  1 
ATOM   6618 C  C   . ILE B 1 350 ? 65.49354  -27.99189 -56.01352 1.000 29.93948  ?  350 ILE B C   1 
ATOM   6619 O  O   . ILE B 1 350 ? 66.08172  -29.07481 -55.88879 1.000 33.26463  ?  350 ILE B O   1 
ATOM   6620 C  CB  . ILE B 1 350 ? 63.48218  -28.58023 -54.65065 1.000 31.05325  ?  350 ILE B CB  1 
ATOM   6621 C  CG1 . ILE B 1 350 ? 62.66172  -28.82574 -55.91868 1.000 34.74226  ?  350 ILE B CG1 1 
ATOM   6622 C  CG2 . ILE B 1 350 ? 62.58703  -28.16325 -53.49192 1.000 23.36677  ?  350 ILE B CG2 1 
ATOM   6623 C  CD1 . ILE B 1 350 ? 61.64589  -29.94046 -55.78534 1.000 30.50467  ?  350 ILE B CD1 1 
ATOM   6624 N  N   . GLN B 1 351 ? 65.64657  -27.22563 -57.08947 1.000 33.35100  ?  351 GLN B N   1 
ATOM   6625 C  CA  . GLN B 1 351 ? 66.50659  -27.63719 -58.18632 1.000 41.01467  ?  351 GLN B CA  1 
ATOM   6626 C  C   . GLN B 1 351 ? 67.97790  -27.50163 -57.79223 1.000 48.99884  ?  351 GLN B C   1 
ATOM   6627 O  O   . GLN B 1 351 ? 68.32839  -26.89415 -56.77684 1.000 54.51894  ?  351 GLN B O   1 
ATOM   6628 C  CB  . GLN B 1 351 ? 66.20604  -26.81093 -59.43645 1.000 36.87423  ?  351 GLN B CB  1 
ATOM   6629 C  CG  . GLN B 1 351 ? 64.73169  -26.77947 -59.82774 1.000 33.85618  ?  351 GLN B CG  1 
ATOM   6630 C  CD  . GLN B 1 351 ? 64.20014  -28.13770 -60.25462 1.000 35.97478  ?  351 GLN B CD  1 
ATOM   6631 O  OE1 . GLN B 1 351 ? 63.89610  -28.99179 -59.42061 1.000 33.04066  ?  351 GLN B OE1 1 
ATOM   6632 N  NE2 . GLN B 1 351 ? 64.08107  -28.34044 -61.56196 1.000 33.99658  ?  351 GLN B NE2 1 
ATOM   6633 N  N   . ASN B 1 352 ? 68.84543  -28.09776 -58.60664 1.000 49.99214  ?  352 ASN B N   1 
ATOM   6634 C  CA  . ASN B 1 352 ? 70.29394  -28.02844 -58.40636 1.000 53.14752  ?  352 ASN B CA  1 
ATOM   6635 C  C   . ASN B 1 352 ? 70.94952  -27.41722 -59.63687 1.000 47.89055  ?  352 ASN B C   1 
ATOM   6636 O  O   . ASN B 1 352 ? 71.11377  -28.10426 -60.66130 1.000 46.79570  ?  352 ASN B O   1 
ATOM   6637 C  CB  . ASN B 1 352 ? 70.87239  -29.41353 -58.12478 1.000 64.63853  ?  352 ASN B CB  1 
ATOM   6638 C  CG  . ASN B 1 352 ? 72.35703  -29.37412 -57.82288 1.000 72.35941  ?  352 ASN B CG  1 
ATOM   6639 O  OD1 . ASN B 1 352 ? 72.85974  -28.41106 -57.24285 1.000 55.37850  ?  352 ASN B OD1 1 
ATOM   6640 N  ND2 . ASN B 1 352 ? 73.06934  -30.42210 -58.22135 1.000 71.49747  ?  352 ASN B ND2 1 
ATOM   6641 N  N   . PRO B 1 353 ? 71.34594  -26.13837 -59.59531 1.000 49.60681  ?  353 PRO B N   1 
ATOM   6642 C  CA  . PRO B 1 353 ? 71.23761  -25.19274 -58.47398 1.000 53.63421  ?  353 PRO B CA  1 
ATOM   6643 C  C   . PRO B 1 353 ? 69.81057  -24.68879 -58.28461 1.000 55.55110  ?  353 PRO B C   1 
ATOM   6644 O  O   . PRO B 1 353 ? 69.00254  -24.76146 -59.20708 1.000 51.82967  ?  353 PRO B O   1 
ATOM   6645 C  CB  . PRO B 1 353 ? 72.19704  -24.06866 -58.88764 1.000 46.34691  ?  353 PRO B CB  1 
ATOM   6646 C  CG  . PRO B 1 353 ? 72.11839  -24.06416 -60.38426 1.000 43.41397  ?  353 PRO B CG  1 
ATOM   6647 C  CD  . PRO B 1 353 ? 71.98252  -25.51777 -60.77186 1.000 46.92378  ?  353 PRO B CD  1 
ATOM   6648 N  N   . PRO B 1 354 ? 69.47214  -24.19962 -57.09157 1.000 56.94188  ?  354 PRO B N   1 
ATOM   6649 C  CA  . PRO B 1 354 ? 68.11993  -23.67352 -56.86987 1.000 43.79724  ?  354 PRO B CA  1 
ATOM   6650 C  C   . PRO B 1 354 ? 67.80911  -22.51624 -57.80812 1.000 44.35587  ?  354 PRO B C   1 
ATOM   6651 O  O   . PRO B 1 354 ? 68.65447  -21.65852 -58.07123 1.000 41.18887  ?  354 PRO B O   1 
ATOM   6652 C  CB  . PRO B 1 354 ? 68.15363  -23.21837 -55.40672 1.000 39.61419  ?  354 PRO B CB  1 
ATOM   6653 C  CG  . PRO B 1 354 ? 69.23174  -24.04158 -54.78319 1.000 51.71715  ?  354 PRO B CG  1 
ATOM   6654 C  CD  . PRO B 1 354 ? 70.26925  -24.21554 -55.85334 1.000 55.32509  ?  354 PRO B CD  1 
ATOM   6655 N  N   . TYR B 1 355 ? 66.57777  -22.49910 -58.30805 1.000 41.91873  ?  355 TYR B N   1 
ATOM   6656 C  CA  . TYR B 1 355 ? 66.10510  -21.45621 -59.20527 1.000 38.53526  ?  355 TYR B CA  1 
ATOM   6657 C  C   . TYR B 1 355 ? 65.16831  -20.51967 -58.45590 1.000 39.68134  ?  355 TYR B C   1 
ATOM   6658 O  O   . TYR B 1 355 ? 64.32777  -20.96268 -57.66862 1.000 40.67375  ?  355 TYR B O   1 
ATOM   6659 C  CB  . TYR B 1 355 ? 65.38849  -22.05462 -60.41719 1.000 31.60499  ?  355 TYR B CB  1 
ATOM   6660 C  CG  . TYR B 1 355 ? 65.02287  -21.03262 -61.46860 1.000 28.68548  ?  355 TYR B CG  1 
ATOM   6661 C  CD1 . TYR B 1 355 ? 65.96892  -20.57570 -62.37601 1.000 28.98446  ?  355 TYR B CD1 1 
ATOM   6662 C  CD2 . TYR B 1 355 ? 63.73478  -20.52257 -61.55293 1.000 31.32483  ?  355 TYR B CD2 1 
ATOM   6663 C  CE1 . TYR B 1 355 ? 65.64378  -19.63929 -63.33693 1.000 30.68474  ?  355 TYR B CE1 1 
ATOM   6664 C  CE2 . TYR B 1 355 ? 63.39919  -19.58574 -62.51254 1.000 37.83608  ?  355 TYR B CE2 1 
ATOM   6665 C  CZ  . TYR B 1 355 ? 64.35790  -19.14830 -63.40230 1.000 36.63382  ?  355 TYR B CZ  1 
ATOM   6666 O  OH  . TYR B 1 355 ? 64.03023  -18.21559 -64.35978 1.000 40.37133  ?  355 TYR B OH  1 
ATOM   6667 N  N   . ARG B 1 356 ? 65.31744  -19.22225 -58.70596 1.000 33.00430  ?  356 ARG B N   1 
ATOM   6668 C  CA  . ARG B 1 356 ? 64.55850  -18.19583 -57.99226 1.000 32.08233  ?  356 ARG B CA  1 
ATOM   6669 C  C   . ARG B 1 356 ? 63.47532  -17.66447 -58.92399 1.000 28.16484  ?  356 ARG B C   1 
ATOM   6670 O  O   . ARG B 1 356 ? 63.70446  -16.75215 -59.71719 1.000 28.73257  ?  356 ARG B O   1 
ATOM   6671 C  CB  . ARG B 1 356 ? 65.48130  -17.08510 -57.50700 1.000 39.70615  ?  356 ARG B CB  1 
ATOM   6672 C  CG  . ARG B 1 356 ? 64.85776  -16.19629 -56.45066 1.000 53.90784  ?  356 ARG B CG  1 
ATOM   6673 C  CD  . ARG B 1 356 ? 64.62855  -16.96938 -55.16336 1.000 76.71041  ?  356 ARG B CD  1 
ATOM   6674 N  NE  . ARG B 1 356 ? 63.35681  -16.62329 -54.54175 1.000 75.41206  ?  356 ARG B NE  1 
ATOM   6675 C  CZ  . ARG B 1 356 ? 62.22218  -17.27725 -54.74939 1.000 64.88017  ?  356 ARG B CZ  1 
ATOM   6676 N  NH1 . ARG B 1 356 ? 62.16612  -18.32816 -55.55111 1.000 60.69611  ?  356 ARG B NH1 1 
ATOM   6677 N  NH2 . ARG B 1 356 ? 61.11603  -16.86692 -54.13782 1.000 52.89948  ?  356 ARG B NH2 1 
ATOM   6678 N  N   . LEU B 1 357 ? 62.28160  -18.24450 -58.82510 1.000 27.10419  ?  357 LEU B N   1 
ATOM   6679 C  CA  . LEU B 1 357 ? 61.14649  -17.77726 -59.60948 1.000 28.36625  ?  357 LEU B CA  1 
ATOM   6680 C  C   . LEU B 1 357 ? 60.37332  -16.73878 -58.80839 1.000 29.26443  ?  357 LEU B C   1 
ATOM   6681 O  O   . LEU B 1 357 ? 59.82598  -17.07498 -57.74959 1.000 29.63898  ?  357 LEU B O   1 
ATOM   6682 C  CB  . LEU B 1 357 ? 60.23447  -18.93301 -59.98449 1.000 25.62797  ?  357 LEU B CB  1 
ATOM   6683 C  CG  . LEU B 1 357 ? 59.12220  -18.60192 -60.98422 1.000 24.51726  ?  357 LEU B CG  1 
ATOM   6684 C  CD1 . LEU B 1 357 ? 59.71265  -18.20967 -62.33039 1.000 23.90492  ?  357 LEU B CD1 1 
ATOM   6685 C  CD2 . LEU B 1 357 ? 58.15361  -19.76574 -61.13718 1.000 26.02734  ?  357 LEU B CD2 1 
ATOM   6686 N  N   . PRO B 1 358 ? 60.31064  -15.48525 -59.25496 1.000 26.99402  ?  358 PRO B N   1 
ATOM   6687 C  CA  . PRO B 1 358 ? 59.59849  -14.46135 -58.48302 1.000 26.78220  ?  358 PRO B CA  1 
ATOM   6688 C  C   . PRO B 1 358 ? 58.10824  -14.74945 -58.40823 1.000 36.92800  ?  358 PRO B C   1 
ATOM   6689 O  O   . PRO B 1 358 ? 57.51944  -15.35670 -59.30619 1.000 38.60144  ?  358 PRO B O   1 
ATOM   6690 C  CB  . PRO B 1 358 ? 59.87343  -13.16855 -59.26252 1.000 28.97264  ?  358 PRO B CB  1 
ATOM   6691 C  CG  . PRO B 1 358 ? 61.06044  -13.47466 -60.12476 1.000 37.42027  ?  358 PRO B CG  1 
ATOM   6692 C  CD  . PRO B 1 358 ? 60.94370  -14.92708 -60.45991 1.000 36.72144  ?  358 PRO B CD  1 
ATOM   6693 N  N   . TYR B 1 359 ? 57.49806  -14.30074 -57.31419 1.000 29.72201  ?  359 TYR B N   1 
ATOM   6694 C  CA  . TYR B 1 359 ? 56.08271  -14.52206 -57.06607 1.000 27.16842  ?  359 TYR B CA  1 
ATOM   6695 C  C   . TYR B 1 359 ? 55.39812  -13.20111 -56.74891 1.000 26.32657  ?  359 TYR B C   1 
ATOM   6696 O  O   . TYR B 1 359 ? 55.99150  -12.30182 -56.14925 1.000 29.29604  ?  359 TYR B O   1 
ATOM   6697 C  CB  . TYR B 1 359 ? 55.86917  -15.51898 -55.92066 1.000 26.80754  ?  359 TYR B CB  1 
ATOM   6698 C  CG  . TYR B 1 359 ? 56.19900  -16.94601 -56.29481 1.000 24.84741  ?  359 TYR B CG  1 
ATOM   6699 C  CD1 . TYR B 1 359 ? 55.77074  -17.48282 -57.50243 1.000 24.61828  ?  359 TYR B CD1 1 
ATOM   6700 C  CD2 . TYR B 1 359 ? 56.94372  -17.75415 -55.44594 1.000 27.92732  ?  359 TYR B CD2 1 
ATOM   6701 C  CE1 . TYR B 1 359 ? 56.06830  -18.78711 -57.85163 1.000 28.24442  ?  359 TYR B CE1 1 
ATOM   6702 C  CE2 . TYR B 1 359 ? 57.24760  -19.05997 -55.78697 1.000 37.23847  ?  359 TYR B CE2 1 
ATOM   6703 C  CZ  . TYR B 1 359 ? 56.80733  -19.57118 -56.99086 1.000 35.90762  ?  359 TYR B CZ  1 
ATOM   6704 O  OH  . TYR B 1 359 ? 57.10663  -20.87039 -57.33446 1.000 29.50401  ?  359 TYR B OH  1 
ATOM   6705 N  N   . PHE B 1 360 ? 54.14022  -13.09507 -57.16736 1.000 28.00561  ?  360 PHE B N   1 
ATOM   6706 C  CA  . PHE B 1 360 ? 53.30698  -11.91191 -56.97112 1.000 27.85696  ?  360 PHE B CA  1 
ATOM   6707 C  C   . PHE B 1 360 ? 51.94567  -12.32025 -56.42260 1.000 23.62648  ?  360 PHE B C   1 
ATOM   6708 O  O   . PHE B 1 360 ? 50.89497  -11.90610 -56.91626 1.000 22.97579  ?  360 PHE B O   1 
ATOM   6709 C  CB  . PHE B 1 360 ? 53.15743  -11.13044 -58.27424 1.000 27.04298  ?  360 PHE B CB  1 
ATOM   6710 C  CG  . PHE B 1 360 ? 54.46450  -10.68926 -58.87434 1.000 30.37346  ?  360 PHE B CG  1 
ATOM   6711 C  CD1 . PHE B 1 360 ? 55.03313  -9.47709  -58.51716 1.000 32.73358  ?  360 PHE B CD1 1 
ATOM   6712 C  CD2 . PHE B 1 360 ? 55.12078  -11.48363 -59.80029 1.000 26.32221  ?  360 PHE B CD2 1 
ATOM   6713 C  CE1 . PHE B 1 360 ? 56.23306  -9.06792  -59.06930 1.000 29.48271  ?  360 PHE B CE1 1 
ATOM   6714 C  CE2 . PHE B 1 360 ? 56.32010  -11.07944 -60.35585 1.000 27.10612  ?  360 PHE B CE2 1 
ATOM   6715 C  CZ  . PHE B 1 360 ? 56.87665  -9.87040  -59.99002 1.000 26.94738  ?  360 PHE B CZ  1 
ATOM   6716 N  N   . PHE B 1 361 ? 51.96422  -13.14679 -55.37712 1.000 24.58974  ?  361 PHE B N   1 
ATOM   6717 C  CA  . PHE B 1 361 ? 50.76634  -13.84051 -54.91588 1.000 29.68577  ?  361 PHE B CA  1 
ATOM   6718 C  C   . PHE B 1 361 ? 49.65146  -12.87928 -54.51781 1.000 25.60196  ?  361 PHE B C   1 
ATOM   6719 O  O   . PHE B 1 361 ? 49.87136  -11.92839 -53.76167 1.000 23.87137  ?  361 PHE B O   1 
ATOM   6720 C  CB  . PHE B 1 361 ? 51.11487  -14.73270 -53.72347 1.000 26.70581  ?  361 PHE B CB  1 
ATOM   6721 C  CG  . PHE B 1 361 ? 51.97681  -15.90967 -54.07172 1.000 24.27590  ?  361 PHE B CG  1 
ATOM   6722 C  CD1 . PHE B 1 361 ? 51.71205  -16.67342 -55.19488 1.000 23.90622  ?  361 PHE B CD1 1 
ATOM   6723 C  CD2 . PHE B 1 361 ? 53.05199  -16.25426 -53.27076 1.000 27.48741  ?  361 PHE B CD2 1 
ATOM   6724 C  CE1 . PHE B 1 361 ? 52.50308  -17.75987 -55.51142 1.000 23.66697  ?  361 PHE B CE1 1 
ATOM   6725 C  CE2 . PHE B 1 361 ? 53.84726  -17.33684 -53.58307 1.000 21.94796  ?  361 PHE B CE2 1 
ATOM   6726 C  CZ  . PHE B 1 361 ? 53.57124  -18.09195 -54.70348 1.000 24.15021  ?  361 PHE B CZ  1 
ATOM   6727 N  N   . HIS B 1 362 ? 48.44737  -13.13743 -55.03007 1.000 20.45808  ?  362 HIS B N   1 
ATOM   6728 C  CA  . HIS B 1 362 ? 47.23807  -12.63530 -54.39043 1.000 25.90729  ?  362 HIS B CA  1 
ATOM   6729 C  C   . HIS B 1 362 ? 47.11531  -13.31424 -53.03102 1.000 28.34091  ?  362 HIS B C   1 
ATOM   6730 O  O   . HIS B 1 362 ? 47.08704  -14.54720 -52.95236 1.000 35.73328  ?  362 HIS B O   1 
ATOM   6731 C  CB  . HIS B 1 362 ? 46.00254  -12.92983 -55.24527 1.000 22.48815  ?  362 HIS B CB  1 
ATOM   6732 C  CG  . HIS B 1 362 ? 45.77058  -11.95972 -56.36726 1.000 17.77191  ?  362 HIS B CG  1 
ATOM   6733 N  ND1 . HIS B 1 362 ? 46.66367  -11.78572 -57.40178 1.000 17.74790  ?  362 HIS B ND1 1 
ATOM   6734 C  CD2 . HIS B 1 362 ? 44.72656  -11.13579 -56.63213 1.000 20.86750  ?  362 HIS B CD2 1 
ATOM   6735 C  CE1 . HIS B 1 362 ? 46.18875  -10.88671 -58.24681 1.000 22.71107  ?  362 HIS B CE1 1 
ATOM   6736 N  NE2 . HIS B 1 362 ? 45.01442  -10.47388 -57.80298 1.000 23.55096  ?  362 HIS B NE2 1 
ATOM   6737 N  N   . ALA B 1 363 ? 47.05533  -12.52749 -51.95908 1.000 20.65590  ?  363 ALA B N   1 
ATOM   6738 C  CA  . ALA B 1 363 ? 47.10388  -13.09790 -50.61942 1.000 18.37408  ?  363 ALA B CA  1 
ATOM   6739 C  C   . ALA B 1 363 ? 46.11282  -12.40413 -49.69915 1.000 20.95487  ?  363 ALA B C   1 
ATOM   6740 O  O   . ALA B 1 363 ? 46.06666  -11.17178 -49.64665 1.000 25.76612  ?  363 ALA B O   1 
ATOM   6741 C  CB  . ALA B 1 363 ? 48.51801  -13.00014 -50.03562 1.000 20.76597  ?  363 ALA B CB  1 
ATOM   6742 N  N   . ALA B 1 364 ? 45.33283  -13.20864 -48.97273 1.000 19.33962  ?  364 ALA B N   1 
ATOM   6743 C  CA  . ALA B 1 364 ? 44.45487  -12.73508 -47.90066 1.000 17.88639  ?  364 ALA B CA  1 
ATOM   6744 C  C   . ALA B 1 364 ? 43.48719  -11.65583 -48.38289 1.000 19.31075  ?  364 ALA B C   1 
ATOM   6745 O  O   . ALA B 1 364 ? 43.33303  -10.60311 -47.76027 1.000 19.16619  ?  364 ALA B O   1 
ATOM   6746 C  CB  . ALA B 1 364 ? 45.27048  -12.23735 -46.70688 1.000 16.93763  ?  364 ALA B CB  1 
ATOM   6747 N  N   . GLU B 1 365 ? 42.82643  -11.92669 -49.50535 1.000 22.87908  ?  365 GLU B N   1 
ATOM   6748 C  CA  . GLU B 1 365 ? 41.74366  -11.06859 -49.98577 1.000 22.97436  ?  365 GLU B CA  1 
ATOM   6749 C  C   . GLU B 1 365 ? 40.42293  -11.50078 -49.34512 1.000 22.51145  ?  365 GLU B C   1 
ATOM   6750 O  O   . GLU B 1 365 ? 39.46792  -11.90185 -50.01006 1.000 24.47573  ?  365 GLU B O   1 
ATOM   6751 C  CB  . GLU B 1 365 ? 41.66958  -11.11376 -51.50761 1.000 22.63147  ?  365 GLU B CB  1 
ATOM   6752 C  CG  . GLU B 1 365 ? 40.82962  -10.00873 -52.12286 1.000 26.61762  ?  365 GLU B CG  1 
ATOM   6753 C  CD  . GLU B 1 365 ? 40.50195  -10.26602 -53.57799 1.000 35.59957  ?  365 GLU B CD  1 
ATOM   6754 O  OE1 . GLU B 1 365 ? 40.81202  -11.37196 -54.06878 1.000 37.18402  ?  365 GLU B OE1 1 
ATOM   6755 O  OE2 . GLU B 1 365 ? 39.93253  -9.36374  -54.22901 1.000 30.44510  -1 365 GLU B OE2 1 
ATOM   6756 N  N   . THR B 1 366 ? 40.38771  -11.41336 -48.01592 1.000 21.71454  ?  366 THR B N   1 
ATOM   6757 C  CA  . THR B 1 366 ? 39.32663  -12.04455 -47.24613 1.000 22.01527  ?  366 THR B CA  1 
ATOM   6758 C  C   . THR B 1 366 ? 38.98781  -11.20477 -46.02356 1.000 17.95151  ?  366 THR B C   1 
ATOM   6759 O  O   . THR B 1 366 ? 39.79947  -10.41008 -45.54217 1.000 14.44106  ?  366 THR B O   1 
ATOM   6760 C  CB  . THR B 1 366 ? 39.73165  -13.45668 -46.80750 1.000 23.19122  ?  366 THR B CB  1 
ATOM   6761 O  OG1 . THR B 1 366 ? 38.67401  -14.04881 -46.04642 1.000 33.28418  ?  366 THR B OG1 1 
ATOM   6762 C  CG2 . THR B 1 366 ? 40.99251  -13.40636 -45.95489 1.000 20.15170  ?  366 THR B CG2 1 
ATOM   6763 N  N   . ASN B 1 367 ? 37.76794  -11.39983 -45.52547 1.000 20.14545  ?  367 ASN B N   1 
ATOM   6764 C  CA  . ASN B 1 367 ? 37.33207  -10.84236 -44.25284 1.000 24.67498  ?  367 ASN B CA  1 
ATOM   6765 C  C   . ASN B 1 367 ? 37.54120  -11.80168 -43.08719 1.000 28.42610  ?  367 ASN B C   1 
ATOM   6766 O  O   . ASN B 1 367 ? 37.18722  -11.46069 -41.95352 1.000 33.84735  ?  367 ASN B O   1 
ATOM   6767 C  CB  . ASN B 1 367 ? 35.85296  -10.44428 -44.32430 1.000 21.74645  ?  367 ASN B CB  1 
ATOM   6768 C  CG  . ASN B 1 367 ? 35.61760  -9.20973  -45.17064 1.000 20.95185  ?  367 ASN B CG  1 
ATOM   6769 O  OD1 . ASN B 1 367 ? 36.41568  -8.27306  -45.15848 1.000 28.42685  ?  367 ASN B OD1 1 
ATOM   6770 N  ND2 . ASN B 1 367 ? 34.51307  -9.19975  -45.90770 1.000 19.67718  ?  367 ASN B ND2 1 
ATOM   6771 N  N   . TRP B 1 368 ? 38.09783  -12.98595 -43.33599 1.000 27.51489  ?  368 TRP B N   1 
ATOM   6772 C  CA  . TRP B 1 368 ? 38.30273  -13.97804 -42.29240 1.000 23.95902  ?  368 TRP B CA  1 
ATOM   6773 C  C   . TRP B 1 368 ? 39.59079  -13.69622 -41.52170 1.000 24.87062  ?  368 TRP B C   1 
ATOM   6774 O  O   . TRP B 1 368 ? 40.42270  -12.87500 -41.91785 1.000 27.65540  ?  368 TRP B O   1 
ATOM   6775 C  CB  . TRP B 1 368 ? 38.34767  -15.38761 -42.88402 1.000 19.63313  ?  368 TRP B CB  1 
ATOM   6776 C  CG  . TRP B 1 368 ? 37.07394  -15.81812 -43.54082 1.000 19.01790  ?  368 TRP B CG  1 
ATOM   6777 C  CD1 . TRP B 1 368 ? 36.88552  -16.09450 -44.86393 1.000 16.39523  ?  368 TRP B CD1 1 
ATOM   6778 C  CD2 . TRP B 1 368 ? 35.80747  -16.02023 -42.90496 1.000 19.37351  ?  368 TRP B CD2 1 
ATOM   6779 N  NE1 . TRP B 1 368 ? 35.58090  -16.45652 -45.09129 1.000 16.79334  ?  368 TRP B NE1 1 
ATOM   6780 C  CE2 . TRP B 1 368 ? 34.89795  -16.41885 -43.90420 1.000 18.45061  ?  368 TRP B CE2 1 
ATOM   6781 C  CE3 . TRP B 1 368 ? 35.35406  -15.90310 -41.58763 1.000 17.11759  ?  368 TRP B CE3 1 
ATOM   6782 C  CZ2 . TRP B 1 368 ? 33.56393  -16.70136 -43.62754 1.000 18.28832  ?  368 TRP B CZ2 1 
ATOM   6783 C  CZ3 . TRP B 1 368 ? 34.02993  -16.18385 -41.31566 1.000 16.17332  ?  368 TRP B CZ3 1 
ATOM   6784 C  CH2 . TRP B 1 368 ? 33.15022  -16.57802 -42.33078 1.000 18.85377  ?  368 TRP B CH2 1 
ATOM   6785 N  N   . GLN B 1 369 ? 39.74819  -14.39950 -40.40055 1.000 24.38812  ?  369 GLN B N   1 
ATOM   6786 C  CA  . GLN B 1 369 ? 40.93502  -14.28961 -39.56535 1.000 19.68882  ?  369 GLN B CA  1 
ATOM   6787 C  C   . GLN B 1 369 ? 41.33272  -15.67143 -39.06783 1.000 20.29270  ?  369 GLN B C   1 
ATOM   6788 O  O   . GLN B 1 369 ? 40.47599  -16.46552 -38.66880 1.000 21.22226  ?  369 GLN B O   1 
ATOM   6789 C  CB  . GLN B 1 369 ? 40.69794  -13.34795 -38.37634 1.000 20.11856  ?  369 GLN B CB  1 
ATOM   6790 C  CG  . GLN B 1 369 ? 41.95152  -13.01754 -37.58075 1.000 17.60444  ?  369 GLN B CG  1 
ATOM   6791 C  CD  . GLN B 1 369 ? 41.66901  -12.11284 -36.39615 1.000 21.67395  ?  369 GLN B CD  1 
ATOM   6792 O  OE1 . GLN B 1 369 ? 40.52266  -11.73871 -36.14432 1.000 25.19116  ?  369 GLN B OE1 1 
ATOM   6793 N  NE2 . GLN B 1 369 ? 42.71652  -11.75629 -35.66118 1.000 18.58015  ?  369 GLN B NE2 1 
ATOM   6794 N  N   . GLU B 1 370 ? 42.63917  -15.94540 -39.09615 1.000 21.66665  ?  370 GLU B N   1 
ATOM   6795 C  CA  . GLU B 1 370 ? 43.21005  -17.21523 -38.63445 1.000 24.20626  ?  370 GLU B CA  1 
ATOM   6796 C  C   . GLU B 1 370 ? 42.61090  -18.41426 -39.36871 1.000 18.32019  ?  370 GLU B C   1 
ATOM   6797 O  O   . GLU B 1 370 ? 42.38643  -19.47571 -38.78364 1.000 19.06936  ?  370 GLU B O   1 
ATOM   6798 C  CB  . GLU B 1 370 ? 43.05598  -17.37638 -37.12082 1.000 19.44186  ?  370 GLU B CB  1 
ATOM   6799 C  CG  . GLU B 1 370 ? 43.87624  -16.39331 -36.30642 1.000 18.42037  ?  370 GLU B CG  1 
ATOM   6800 C  CD  . GLU B 1 370 ? 43.66565  -16.56094 -34.81616 1.000 26.81471  ?  370 GLU B CD  1 
ATOM   6801 O  OE1 . GLU B 1 370 ? 43.00412  -17.54263 -34.41773 1.000 25.52319  ?  370 GLU B OE1 1 
ATOM   6802 O  OE2 . GLU B 1 370 ? 44.15519  -15.70958 -34.04392 1.000 36.53288  -1 370 GLU B OE2 1 
ATOM   6803 N  N   . THR B 1 371 ? 42.36066  -18.24916 -40.66085 1.000 16.94274  ?  371 THR B N   1 
ATOM   6804 C  CA  . THR B 1 371 ? 41.92906  -19.32920 -41.53621 1.000 19.44104  ?  371 THR B CA  1 
ATOM   6805 C  C   . THR B 1 371 ? 43.01211  -19.58005 -42.57960 1.000 25.17324  ?  371 THR B C   1 
ATOM   6806 O  O   . THR B 1 371 ? 44.06147  -18.93479 -42.58018 1.000 21.93724  ?  371 THR B O   1 
ATOM   6807 C  CB  . THR B 1 371 ? 40.59372  -18.99924 -42.21015 1.000 21.64271  ?  371 THR B CB  1 
ATOM   6808 O  OG1 . THR B 1 371 ? 40.80440  -18.02841 -43.24366 1.000 20.10501  ?  371 THR B OG1 1 
ATOM   6809 C  CG2 . THR B 1 371 ? 39.60621  -18.44564 -41.19436 1.000 17.61912  ?  371 THR B CG2 1 
ATOM   6810 N  N   . GLU B 1 372 ? 42.74507  -20.52851 -43.48079 1.000 27.60504  ?  372 GLU B N   1 
ATOM   6811 C  CA  . GLU B 1 372 ? 43.68189  -20.79320 -44.56865 1.000 20.40131  ?  372 GLU B CA  1 
ATOM   6812 C  C   . GLU B 1 372 ? 43.87088  -19.56183 -45.44415 1.000 24.30142  ?  372 GLU B C   1 
ATOM   6813 O  O   . GLU B 1 372 ? 44.98413  -19.28366 -45.90899 1.000 29.85190  ?  372 GLU B O   1 
ATOM   6814 C  CB  . GLU B 1 372 ? 43.19151  -21.96704 -45.41602 1.000 23.15819  ?  372 GLU B CB  1 
ATOM   6815 C  CG  . GLU B 1 372 ? 43.66551  -23.33293 -44.95873 1.000 30.78042  ?  372 GLU B CG  1 
ATOM   6816 C  CD  . GLU B 1 372 ? 43.30466  -24.42172 -45.95034 1.000 22.96744  ?  372 GLU B CD  1 
ATOM   6817 O  OE1 . GLU B 1 372 ? 42.23888  -24.31174 -46.59413 1.000 14.46512  ?  372 GLU B OE1 1 
ATOM   6818 O  OE2 . GLU B 1 372 ? 44.09223  -25.37923 -46.09627 1.000 27.13186  -1 372 GLU B OE2 1 
ATOM   6819 N  N   . VAL B 1 373 ? 42.79328  -18.80571 -45.66804 1.000 23.86839  ?  373 VAL B N   1 
ATOM   6820 C  CA  . VAL B 1 373 ? 42.82312  -17.72569 -46.65105 1.000 24.85024  ?  373 VAL B CA  1 
ATOM   6821 C  C   . VAL B 1 373 ? 43.81605  -16.64706 -46.23613 1.000 20.18323  ?  373 VAL B C   1 
ATOM   6822 O  O   . VAL B 1 373 ? 44.68269  -16.24329 -47.02022 1.000 15.06824  ?  373 VAL B O   1 
ATOM   6823 C  CB  . VAL B 1 373 ? 41.41174  -17.14533 -46.84851 1.000 21.32985  ?  373 VAL B CB  1 
ATOM   6824 C  CG1 . VAL B 1 373 ? 41.34436  -16.35624 -48.14259 1.000 19.75117  ?  373 VAL B CG1 1 
ATOM   6825 C  CG2 . VAL B 1 373 ? 40.37603  -18.25618 -46.83768 1.000 19.65592  ?  373 VAL B CG2 1 
ATOM   6826 N  N   . ASP B 1 374 ? 43.71280  -16.16842 -44.99490 1.000 24.18365  ?  374 ASP B N   1 
ATOM   6827 C  CA  . ASP B 1 374 ? 44.63140  -15.13473 -44.53454 1.000 25.95690  ?  374 ASP B CA  1 
ATOM   6828 C  C   . ASP B 1 374 ? 45.97412  -15.69793 -44.08703 1.000 26.08059  ?  374 ASP B C   1 
ATOM   6829 O  O   . ASP B 1 374 ? 46.96471  -14.95879 -44.07760 1.000 26.53447  ?  374 ASP B O   1 
ATOM   6830 C  CB  . ASP B 1 374 ? 44.00469  -14.30957 -43.40438 1.000 23.01236  ?  374 ASP B CB  1 
ATOM   6831 C  CG  . ASP B 1 374 ? 43.40773  -15.16476 -42.30752 1.000 18.84964  ?  374 ASP B CG  1 
ATOM   6832 O  OD1 . ASP B 1 374 ? 42.37347  -15.81767 -42.55417 1.000 21.47075  ?  374 ASP B OD1 1 
ATOM   6833 O  OD2 . ASP B 1 374 ? 43.97251  -15.17674 -41.19419 1.000 16.56672  -1 374 ASP B OD2 1 
ATOM   6834 N  N   . TYR B 1 375 ? 46.03615  -16.98100 -43.72283 1.000 23.44363  ?  375 TYR B N   1 
ATOM   6835 C  CA  . TYR B 1 375 ? 47.31970  -17.62055 -43.46302 1.000 24.66004  ?  375 TYR B CA  1 
ATOM   6836 C  C   . TYR B 1 375 ? 48.08263  -17.93541 -44.74181 1.000 21.25112  ?  375 TYR B C   1 
ATOM   6837 O  O   . TYR B 1 375 ? 49.23330  -18.37880 -44.66291 1.000 19.55952  ?  375 TYR B O   1 
ATOM   6838 C  CB  . TYR B 1 375 ? 47.13471  -18.89795 -42.63852 1.000 29.09160  ?  375 TYR B CB  1 
ATOM   6839 C  CG  . TYR B 1 375 ? 47.01999  -18.64896 -41.14845 1.000 23.21665  ?  375 TYR B CG  1 
ATOM   6840 C  CD1 . TYR B 1 375 ? 47.72594  -17.61737 -40.54127 1.000 22.40076  ?  375 TYR B CD1 1 
ATOM   6841 C  CD2 . TYR B 1 375 ? 46.20409  -19.44142 -40.35080 1.000 20.53938  ?  375 TYR B CD2 1 
ATOM   6842 C  CE1 . TYR B 1 375 ? 47.62440  -17.38344 -39.18066 1.000 28.52184  ?  375 TYR B CE1 1 
ATOM   6843 C  CE2 . TYR B 1 375 ? 46.09610  -19.21556 -38.99041 1.000 25.41302  ?  375 TYR B CE2 1 
ATOM   6844 C  CZ  . TYR B 1 375 ? 46.80711  -18.18551 -38.41010 1.000 28.56485  ?  375 TYR B CZ  1 
ATOM   6845 O  OH  . TYR B 1 375 ? 46.69937  -17.95999 -37.05550 1.000 20.45169  ?  375 TYR B OH  1 
ATOM   6846 N  N   . ASN B 1 376 ? 47.47005  -17.72925 -45.91175 1.000 22.56930  ?  376 ASN B N   1 
ATOM   6847 C  CA  . ASN B 1 376 ? 48.24086  -17.71180 -47.15029 1.000 20.20077  ?  376 ASN B CA  1 
ATOM   6848 C  C   . ASN B 1 376 ? 49.30959  -16.62760 -47.13336 1.000 18.85134  ?  376 ASN B C   1 
ATOM   6849 O  O   . ASN B 1 376 ? 50.27023  -16.70569 -47.90641 1.000 25.59487  ?  376 ASN B O   1 
ATOM   6850 C  CB  . ASN B 1 376 ? 47.32262  -17.50363 -48.35719 1.000 20.62940  ?  376 ASN B CB  1 
ATOM   6851 C  CG  . ASN B 1 376 ? 46.47010  -18.71725 -48.65968 1.000 23.67876  ?  376 ASN B CG  1 
ATOM   6852 O  OD1 . ASN B 1 376 ? 46.79595  -19.83272 -48.25591 1.000 29.06778  ?  376 ASN B OD1 1 
ATOM   6853 N  ND2 . ASN B 1 376 ? 45.37431  -18.50752 -49.38269 1.000 17.07107  ?  376 ASN B ND2 1 
ATOM   6854 N  N   . LEU B 1 377 ? 49.15430  -15.61230 -46.27933 1.000 18.71366  ?  377 LEU B N   1 
ATOM   6855 C  CA  . LEU B 1 377 ? 50.18101  -14.58446 -46.14501 1.000 21.72708  ?  377 LEU B CA  1 
ATOM   6856 C  C   . LEU B 1 377 ? 51.49936  -15.17359 -45.66639 1.000 24.88359  ?  377 LEU B C   1 
ATOM   6857 O  O   . LEU B 1 377 ? 52.56945  -14.77432 -46.13706 1.000 25.88667  ?  377 LEU B O   1 
ATOM   6858 C  CB  . LEU B 1 377 ? 49.71382  -13.49814 -45.18122 1.000 17.38349  ?  377 LEU B CB  1 
ATOM   6859 C  CG  . LEU B 1 377 ? 48.72240  -12.48446 -45.73714 1.000 17.44300  ?  377 LEU B CG  1 
ATOM   6860 C  CD1 . LEU B 1 377 ? 48.14734  -11.66655 -44.60292 1.000 22.03720  ?  377 LEU B CD1 1 
ATOM   6861 C  CD2 . LEU B 1 377 ? 49.40344  -11.58907 -46.75776 1.000 14.84147  ?  377 LEU B CD2 1 
ATOM   6862 N  N   . ALA B 1 378 ? 51.44641  -16.10321 -44.70941 1.000 24.50990  ?  378 ALA B N   1 
ATOM   6863 C  CA  . ALA B 1 378 ? 52.67298  -16.73280 -44.23242 1.000 20.12430  ?  378 ALA B CA  1 
ATOM   6864 C  C   . ALA B 1 378 ? 53.37727  -17.47776 -45.35792 1.000 21.10934  ?  378 ALA B C   1 
ATOM   6865 O  O   . ALA B 1 378 ? 54.59839  -17.36425 -45.52000 1.000 28.04430  ?  378 ALA B O   1 
ATOM   6866 C  CB  . ALA B 1 378 ? 52.36383  -17.67698 -43.07143 1.000 21.01010  ?  378 ALA B CB  1 
ATOM   6867 N  N   . ASP B 1 379 ? 52.61932  -18.23058 -46.15849 1.000 13.98785  ?  379 ASP B N   1 
ATOM   6868 C  CA  . ASP B 1 379 ? 53.21250  -18.92954 -47.29247 1.000 15.32403  ?  379 ASP B CA  1 
ATOM   6869 C  C   . ASP B 1 379 ? 53.79804  -17.95013 -48.30032 1.000 23.06519  ?  379 ASP B C   1 
ATOM   6870 O  O   . ASP B 1 379 ? 54.89553  -18.17108 -48.82401 1.000 22.78678  ?  379 ASP B O   1 
ATOM   6871 C  CB  . ASP B 1 379 ? 52.17221  -19.82725 -47.95926 1.000 14.88152  ?  379 ASP B CB  1 
ATOM   6872 C  CG  . ASP B 1 379 ? 51.71673  -20.95407 -47.05889 1.000 23.55653  ?  379 ASP B CG  1 
ATOM   6873 O  OD1 . ASP B 1 379 ? 52.52945  -21.41149 -46.22893 1.000 21.70161  ?  379 ASP B OD1 1 
ATOM   6874 O  OD2 . ASP B 1 379 ? 50.54937  -21.38215 -47.18058 1.000 31.86463  -1 379 ASP B OD2 1 
ATOM   6875 N  N   . ALA B 1 380 ? 53.08131  -16.85948 -48.58276 1.000 22.10096  ?  380 ALA B N   1 
ATOM   6876 C  CA  . ALA B 1 380 ? 53.57948  -15.87513 -49.53792 1.000 23.06046  ?  380 ALA B CA  1 
ATOM   6877 C  C   . ALA B 1 380 ? 54.87513  -15.23849 -49.04993 1.000 25.75599  ?  380 ALA B C   1 
ATOM   6878 O  O   . ALA B 1 380 ? 55.82039  -15.06058 -49.82722 1.000 25.87353  ?  380 ALA B O   1 
ATOM   6879 C  CB  . ALA B 1 380 ? 52.51525  -14.80785 -49.79449 1.000 17.18860  ?  380 ALA B CB  1 
ATOM   6880 N  N   . LEU B 1 381 ? 54.93832  -14.89216 -47.76301 1.000 21.46790  ?  381 LEU B N   1 
ATOM   6881 C  CA  . LEU B 1 381 ? 56.15144  -14.29981 -47.20955 1.000 27.70752  ?  381 LEU B CA  1 
ATOM   6882 C  C   . LEU B 1 381 ? 57.31169  -15.28658 -47.22807 1.000 26.83223  ?  381 LEU B C   1 
ATOM   6883 O  O   . LEU B 1 381 ? 58.44412  -14.91464 -47.55860 1.000 29.76314  ?  381 LEU B O   1 
ATOM   6884 C  CB  . LEU B 1 381 ? 55.89013  -13.80673 -45.78726 1.000 28.78861  ?  381 LEU B CB  1 
ATOM   6885 C  CG  . LEU B 1 381 ? 54.88892  -12.65959 -45.65419 1.000 21.30219  ?  381 LEU B CG  1 
ATOM   6886 C  CD1 . LEU B 1 381 ? 54.67504  -12.29840 -44.19198 1.000 22.50678  ?  381 LEU B CD1 1 
ATOM   6887 C  CD2 . LEU B 1 381 ? 55.36031  -11.45516 -46.45012 1.000 19.94677  ?  381 LEU B CD2 1 
ATOM   6888 N  N   . LEU B 1 382 ? 57.05037  -16.54912 -46.87939 1.000 22.52038  ?  382 LEU B N   1 
ATOM   6889 C  CA  . LEU B 1 382 ? 58.12170  -17.53895 -46.84353 1.000 26.93770  ?  382 LEU B CA  1 
ATOM   6890 C  C   . LEU B 1 382 ? 58.59140  -17.92055 -48.23897 1.000 27.39875  ?  382 LEU B C   1 
ATOM   6891 O  O   . LEU B 1 382 ? 59.73712  -18.35218 -48.40638 1.000 29.13903  ?  382 LEU B O   1 
ATOM   6892 C  CB  . LEU B 1 382 ? 57.66093  -18.77983 -46.08606 1.000 22.21184  ?  382 LEU B CB  1 
ATOM   6893 C  CG  . LEU B 1 382 ? 57.38879  -18.56282 -44.60312 1.000 15.15100  ?  382 LEU B CG  1 
ATOM   6894 C  CD1 . LEU B 1 382 ? 56.48218  -19.65722 -44.11332 1.000 18.58214  ?  382 LEU B CD1 1 
ATOM   6895 C  CD2 . LEU B 1 382 ? 58.68503  -18.53883 -43.81564 1.000 17.38229  ?  382 LEU B CD2 1 
ATOM   6896 N  N   . LEU B 1 383 ? 57.73041  -17.77896 -49.24465 1.000 23.28107  ?  383 LEU B N   1 
ATOM   6897 C  CA  . LEU B 1 383 ? 58.10561  -18.02332 -50.62834 1.000 27.14125  ?  383 LEU B CA  1 
ATOM   6898 C  C   . LEU B 1 383 ? 58.75113  -16.80436 -51.27998 1.000 26.68897  ?  383 LEU B C   1 
ATOM   6899 O  O   . LEU B 1 383 ? 58.84390  -16.74915 -52.51149 1.000 20.00310  ?  383 LEU B O   1 
ATOM   6900 C  CB  . LEU B 1 383 ? 56.88715  -18.47814 -51.43401 1.000 25.94337  ?  383 LEU B CB  1 
ATOM   6901 C  CG  . LEU B 1 383 ? 56.33076  -19.85424 -51.05702 1.000 22.13342  ?  383 LEU B CG  1 
ATOM   6902 C  CD1 . LEU B 1 383 ? 55.07164  -20.16736 -51.84668 1.000 20.52580  ?  383 LEU B CD1 1 
ATOM   6903 C  CD2 . LEU B 1 383 ? 57.37509  -20.94023 -51.26071 1.000 21.03145  ?  383 LEU B CD2 1 
ATOM   6904 N  N   . ASN B 1 384 ? 59.18300  -15.82746 -50.47667 1.000 27.36247  ?  384 ASN B N   1 
ATOM   6905 C  CA  . ASN B 1 384 ? 59.94553  -14.67049 -50.95050 1.000 32.74732  ?  384 ASN B CA  1 
ATOM   6906 C  C   . ASN B 1 384 ? 59.21056  -13.92294 -52.06414 1.000 28.47020  ?  384 ASN B C   1 
ATOM   6907 O  O   . ASN B 1 384 ? 59.78599  -13.58432 -53.10080 1.000 25.99420  ?  384 ASN B O   1 
ATOM   6908 C  CB  . ASN B 1 384 ? 61.34426  -15.09177 -51.40832 1.000 36.20670  ?  384 ASN B CB  1 
ATOM   6909 C  CG  . ASN B 1 384 ? 62.19013  -15.64980 -50.27923 1.000 36.95765  ?  384 ASN B CG  1 
ATOM   6910 O  OD1 . ASN B 1 384 ? 62.00774  -15.29668 -49.11313 1.000 28.49922  ?  384 ASN B OD1 1 
ATOM   6911 N  ND2 . ASN B 1 384 ? 63.12651  -16.52837 -50.62577 1.000 45.49846  ?  384 ASN B ND2 1 
ATOM   6912 N  N   . THR B 1 385 ? 57.92443  -13.66381 -51.84304 1.000 25.24437  ?  385 THR B N   1 
ATOM   6913 C  CA  . THR B 1 385 ? 57.12987  -12.96328 -52.84253 1.000 28.66017  ?  385 THR B CA  1 
ATOM   6914 C  C   . THR B 1 385 ? 57.61616  -11.52524 -52.99925 1.000 30.20842  ?  385 THR B C   1 
ATOM   6915 O  O   . THR B 1 385 ? 58.01893  -10.87493 -52.02996 1.000 32.87295  ?  385 THR B O   1 
ATOM   6916 C  CB  . THR B 1 385 ? 55.64422  -12.99428 -52.46635 1.000 26.06502  ?  385 THR B CB  1 
ATOM   6917 O  OG1 . THR B 1 385 ? 54.86616  -12.42877 -53.52812 1.000 25.46401  ?  385 THR B OG1 1 
ATOM   6918 C  CG2 . THR B 1 385 ? 55.38222  -12.21701 -51.18080 1.000 22.90721  ?  385 THR B CG2 1 
ATOM   6919 N  N   . THR B 1 386 ? 57.60733  -11.03995 -54.24205 1.000 27.35359  ?  386 THR B N   1 
ATOM   6920 C  CA  . THR B 1 386 ? 58.03926  -9.67125  -54.50600 1.000 27.34106  ?  386 THR B CA  1 
ATOM   6921 C  C   . THR B 1 386 ? 57.02915  -8.66642  -53.96607 1.000 29.58088  ?  386 THR B C   1 
ATOM   6922 O  O   . THR B 1 386 ? 57.39913  -7.69696  -53.29316 1.000 30.67856  ?  386 THR B O   1 
ATOM   6923 C  CB  . THR B 1 386 ? 58.25198  -9.46884  -56.00701 1.000 34.19381  ?  386 THR B CB  1 
ATOM   6924 O  OG1 . THR B 1 386 ? 59.14943  -10.46963 -56.50407 1.000 47.48754  ?  386 THR B OG1 1 
ATOM   6925 C  CG2 . THR B 1 386 ? 58.83855  -8.09320  -56.28210 1.000 30.01822  ?  386 THR B CG2 1 
ATOM   6926 N  N   . ARG B 1 387 ? 55.74682  -8.88371  -54.25159 1.000 27.59059  ?  387 ARG B N   1 
ATOM   6927 C  CA  . ARG B 1 387 ? 54.67336  -8.04501  -53.73965 1.000 25.82305  ?  387 ARG B CA  1 
ATOM   6928 C  C   . ARG B 1 387 ? 53.48309  -8.92602  -53.39197 1.000 25.14011  ?  387 ARG B C   1 
ATOM   6929 O  O   . ARG B 1 387 ? 53.38162  -10.07268 -53.83440 1.000 29.69448  ?  387 ARG B O   1 
ATOM   6930 C  CB  . ARG B 1 387 ? 54.24640  -6.96559  -54.74601 1.000 26.86517  ?  387 ARG B CB  1 
ATOM   6931 C  CG  . ARG B 1 387 ? 55.32048  -5.94335  -55.08368 1.000 22.64703  ?  387 ARG B CG  1 
ATOM   6932 C  CD  . ARG B 1 387 ? 54.74627  -4.81454  -55.92171 1.000 21.33728  ?  387 ARG B CD  1 
ATOM   6933 N  NE  . ARG B 1 387 ? 53.99743  -5.31149  -57.07025 1.000 30.80169  ?  387 ARG B NE  1 
ATOM   6934 C  CZ  . ARG B 1 387 ? 54.49578  -5.45060  -58.29129 1.000 24.58341  ?  387 ARG B CZ  1 
ATOM   6935 N  NH1 . ARG B 1 387 ? 55.74918  -5.13101  -58.56749 1.000 27.07803  ?  387 ARG B NH1 1 
ATOM   6936 N  NH2 . ARG B 1 387 ? 53.71585  -5.92103  -59.26014 1.000 19.68415  ?  387 ARG B NH2 1 
ATOM   6937 N  N   . VAL B 1 388 ? 52.57612  -8.37346  -52.59256 1.000 19.90702  ?  388 VAL B N   1 
ATOM   6938 C  CA  . VAL B 1 388 ? 51.37127  -9.06917  -52.15929 1.000 19.45705  ?  388 VAL B CA  1 
ATOM   6939 C  C   . VAL B 1 388 ? 50.16628  -8.34593  -52.73918 1.000 22.27294  ?  388 VAL B C   1 
ATOM   6940 O  O   . VAL B 1 388 ? 50.04303  -7.12402  -52.59800 1.000 23.86965  ?  388 VAL B O   1 
ATOM   6941 C  CB  . VAL B 1 388 ? 51.27660  -9.14377  -50.62443 1.000 18.30270  ?  388 VAL B CB  1 
ATOM   6942 C  CG1 . VAL B 1 388 ? 49.87818  -9.56412  -50.19765 1.000 19.19122  ?  388 VAL B CG1 1 
ATOM   6943 C  CG2 . VAL B 1 388 ? 52.31418  -10.10974 -50.07802 1.000 15.56232  ?  388 VAL B CG2 1 
ATOM   6944 N  N   . GLY B 1 389 ? 49.28635  -9.09864  -53.39713 1.000 21.51482  ?  389 GLY B N   1 
ATOM   6945 C  CA  . GLY B 1 389 ? 48.05582  -8.52681  -53.91433 1.000 18.99667  ?  389 GLY B CA  1 
ATOM   6946 C  C   . GLY B 1 389 ? 47.01801  -8.41785  -52.81417 1.000 22.54950  ?  389 GLY B C   1 
ATOM   6947 O  O   . GLY B 1 389 ? 46.75713  -9.38654  -52.09276 1.000 28.77294  ?  389 GLY B O   1 
ATOM   6948 N  N   . HIS B 1 390 ? 46.44180  -7.22172  -52.67154 1.000 21.24122  ?  390 HIS B N   1 
ATOM   6949 C  CA  . HIS B 1 390 ? 45.36903  -6.92451  -51.72510 1.000 22.44410  ?  390 HIS B CA  1 
ATOM   6950 C  C   . HIS B 1 390 ? 45.85220  -6.95628  -50.27880 1.000 21.52327  ?  390 HIS B C   1 
ATOM   6951 O  O   . HIS B 1 390 ? 46.05499  -5.90001  -49.67245 1.000 24.59935  ?  390 HIS B O   1 
ATOM   6952 C  CB  . HIS B 1 390 ? 44.19339  -7.88575  -51.92408 1.000 18.05193  ?  390 HIS B CB  1 
ATOM   6953 C  CG  . HIS B 1 390 ? 43.70997  -7.95328  -53.33885 1.000 27.20322  ?  390 HIS B CG  1 
ATOM   6954 N  ND1 . HIS B 1 390 ? 42.92540  -6.97160  -53.90500 1.000 28.90735  ?  390 HIS B ND1 1 
ATOM   6955 C  CD2 . HIS B 1 390 ? 43.91064  -8.87898  -54.30654 1.000 28.81144  ?  390 HIS B CD2 1 
ATOM   6956 C  CE1 . HIS B 1 390 ? 42.65881  -7.29253  -55.15860 1.000 29.30624  ?  390 HIS B CE1 1 
ATOM   6957 N  NE2 . HIS B 1 390 ? 43.24471  -8.44550  -55.42725 1.000 23.88994  ?  390 HIS B NE2 1 
ATOM   6958 N  N   . GLY B 1 391 ? 46.03769  -8.14703  -49.71713 1.000 20.65466  ?  391 GLY B N   1 
ATOM   6959 C  CA  . GLY B 1 391 ? 46.46836  -8.25322  -48.32979 1.000 19.52731  ?  391 GLY B CA  1 
ATOM   6960 C  C   . GLY B 1 391 ? 45.51294  -7.60687  -47.35065 1.000 22.07152  ?  391 GLY B C   1 
ATOM   6961 O  O   . GLY B 1 391 ? 45.95119  -6.92955  -46.41187 1.000 17.93197  ?  391 GLY B O   1 
ATOM   6962 N  N   . PHE B 1 392 ? 44.20671  -7.80552  -47.54986 1.000 17.37718  ?  392 PHE B N   1 
ATOM   6963 C  CA  . PHE B 1 392 ? 43.20732  -7.12292  -46.73406 1.000 14.51249  ?  392 PHE B CA  1 
ATOM   6964 C  C   . PHE B 1 392 ? 43.30571  -7.51794  -45.26526 1.000 19.05240  ?  392 PHE B C   1 
ATOM   6965 O  O   . PHE B 1 392 ? 43.00926  -6.70423  -44.38293 1.000 16.35942  ?  392 PHE B O   1 
ATOM   6966 C  CB  . PHE B 1 392 ? 41.80966  -7.42410  -47.27723 1.000 15.40797  ?  392 PHE B CB  1 
ATOM   6967 C  CG  . PHE B 1 392 ? 40.76592  -6.41766  -46.87793 1.000 15.71118  ?  392 PHE B CG  1 
ATOM   6968 C  CD1 . PHE B 1 392 ? 40.05971  -6.55973  -45.69452 1.000 15.34941  ?  392 PHE B CD1 1 
ATOM   6969 C  CD2 . PHE B 1 392 ? 40.47964  -5.33785  -47.69679 1.000 17.44059  ?  392 PHE B CD2 1 
ATOM   6970 C  CE1 . PHE B 1 392 ? 39.09457  -5.63926  -45.33168 1.000 15.00830  ?  392 PHE B CE1 1 
ATOM   6971 C  CE2 . PHE B 1 392 ? 39.51623  -4.41341  -47.33911 1.000 16.52391  ?  392 PHE B CE2 1 
ATOM   6972 C  CZ  . PHE B 1 392 ? 38.82350  -4.56424  -46.15474 1.000 17.09175  ?  392 PHE B CZ  1 
ATOM   6973 N  N   . ALA B 1 393 ? 43.72058  -8.75057  -44.98039 1.000 19.71314  ?  393 ALA B N   1 
ATOM   6974 C  CA  . ALA B 1 393 ? 43.82787  -9.24041  -43.61343 1.000 20.22673  ?  393 ALA B CA  1 
ATOM   6975 C  C   . ALA B 1 393 ? 45.24889  -9.16316  -43.06896 1.000 17.69255  ?  393 ALA B C   1 
ATOM   6976 O  O   . ALA B 1 393 ? 45.51423  -9.68990  -41.98354 1.000 16.90637  ?  393 ALA B O   1 
ATOM   6977 C  CB  . ALA B 1 393 ? 43.31013  -10.67748 -43.52685 1.000 16.20403  ?  393 ALA B CB  1 
ATOM   6978 N  N   . LEU B 1 394 ? 46.16622  -8.51984  -43.79627 1.000 15.29725  ?  394 LEU B N   1 
ATOM   6979 C  CA  . LEU B 1 394 ? 47.54485  -8.41752  -43.32761 1.000 16.25479  ?  394 LEU B CA  1 
ATOM   6980 C  C   . LEU B 1 394 ? 47.62982  -7.64123  -42.02210 1.000 17.15037  ?  394 LEU B C   1 
ATOM   6981 O  O   . LEU B 1 394 ? 48.38711  -8.01291  -41.11803 1.000 19.92748  ?  394 LEU B O   1 
ATOM   6982 C  CB  . LEU B 1 394 ? 48.41805  -7.75825  -44.39423 1.000 15.99483  ?  394 LEU B CB  1 
ATOM   6983 C  CG  . LEU B 1 394 ? 49.83561  -7.39190  -43.94704 1.000 10.86355  ?  394 LEU B CG  1 
ATOM   6984 C  CD1 . LEU B 1 394 ? 50.62807  -8.63856  -43.58568 1.000 9.79551   ?  394 LEU B CD1 1 
ATOM   6985 C  CD2 . LEU B 1 394 ? 50.55073  -6.58238  -45.01622 1.000 13.33996  ?  394 LEU B CD2 1 
ATOM   6986 N  N   . ILE B 1 395 ? 46.85911  -6.55832  -41.90534 1.000 17.59644  ?  395 ILE B N   1 
ATOM   6987 C  CA  . ILE B 1 395 ? 46.90833  -5.73559  -40.70125 1.000 21.19854  ?  395 ILE B CA  1 
ATOM   6988 C  C   . ILE B 1 395 ? 46.43350  -6.52327  -39.48680 1.000 15.47227  ?  395 ILE B C   1 
ATOM   6989 O  O   . ILE B 1 395 ? 46.87401  -6.26815  -38.35925 1.000 13.11333  ?  395 ILE B O   1 
ATOM   6990 C  CB  . ILE B 1 395 ? 46.08990  -4.44526  -40.91594 1.000 21.41962  ?  395 ILE B CB  1 
ATOM   6991 C  CG1 . ILE B 1 395 ? 46.20760  -3.51453  -39.70811 1.000 16.07591  ?  395 ILE B CG1 1 
ATOM   6992 C  CG2 . ILE B 1 395 ? 44.63404  -4.77083  -41.22623 1.000 27.05527  ?  395 ILE B CG2 1 
ATOM   6993 C  CD1 . ILE B 1 395 ? 45.56607  -2.16858  -39.92768 1.000 19.24972  ?  395 ILE B CD1 1 
ATOM   6994 N  N   . LYS B 1 396 ? 45.54897  -7.50276  -39.69258 1.000 18.28751  ?  396 LYS B N   1 
ATOM   6995 C  CA  . LYS B 1 396 ? 45.08249  -8.33217  -38.58684 1.000 16.90789  ?  396 LYS B CA  1 
ATOM   6996 C  C   . LYS B 1 396 ? 46.17575  -9.23633  -38.03309 1.000 16.24367  ?  396 LYS B C   1 
ATOM   6997 O  O   . LYS B 1 396 ? 46.00865  -9.79114  -36.94336 1.000 16.72351  ?  396 LYS B O   1 
ATOM   6998 C  CB  . LYS B 1 396 ? 43.88731  -9.18074  -39.02560 1.000 17.83553  ?  396 LYS B CB  1 
ATOM   6999 C  CG  . LYS B 1 396 ? 42.61317  -8.39152  -39.27406 1.000 14.54397  ?  396 LYS B CG  1 
ATOM   7000 C  CD  . LYS B 1 396 ? 41.46869  -9.31202  -39.67059 1.000 15.21316  ?  396 LYS B CD  1 
ATOM   7001 C  CE  . LYS B 1 396 ? 40.17556  -8.53666  -39.86978 1.000 28.76897  ?  396 LYS B CE  1 
ATOM   7002 N  NZ  . LYS B 1 396 ? 39.05120  -9.41713  -40.29349 1.000 23.33520  ?  396 LYS B NZ  1 
ATOM   7003 N  N   . HIS B 1 397 ? 47.27826  -9.40733  -38.75575 1.000 22.52638  ?  397 HIS B N   1 
ATOM   7004 C  CA  . HIS B 1 397 ? 48.38789  -10.25102 -38.31149 1.000 21.32136  ?  397 HIS B CA  1 
ATOM   7005 C  C   . HIS B 1 397 ? 49.62652  -9.39084  -38.10214 1.000 21.65512  ?  397 HIS B C   1 
ATOM   7006 O  O   . HIS B 1 397 ? 50.27581  -8.98105  -39.08127 1.000 21.74409  ?  397 HIS B O   1 
ATOM   7007 C  CB  . HIS B 1 397 ? 48.65922  -11.35969 -39.32468 1.000 18.30369  ?  397 HIS B CB  1 
ATOM   7008 C  CG  . HIS B 1 397 ? 47.51506  -12.30913 -39.50184 1.000 19.37052  ?  397 HIS B CG  1 
ATOM   7009 N  ND1 . HIS B 1 397 ? 47.20041  -13.27741 -38.57277 1.000 21.35927  ?  397 HIS B ND1 1 
ATOM   7010 C  CD2 . HIS B 1 397 ? 46.61343  -12.44218 -40.50318 1.000 18.56870  ?  397 HIS B CD2 1 
ATOM   7011 C  CE1 . HIS B 1 397 ? 46.15381  -13.96503 -38.99319 1.000 19.88307  ?  397 HIS B CE1 1 
ATOM   7012 N  NE2 . HIS B 1 397 ? 45.77840  -13.47837 -40.16223 1.000 18.81627  ?  397 HIS B NE2 1 
ATOM   7013 N  N   . PRO B 1 398 ? 49.99524  -9.09322  -36.85326 1.000 19.42615  ?  398 PRO B N   1 
ATOM   7014 C  CA  . PRO B 1 398 ? 51.08583  -8.12495  -36.62481 1.000 18.05808  ?  398 PRO B CA  1 
ATOM   7015 C  C   . PRO B 1 398 ? 52.44387  -8.59209  -37.12386 1.000 25.43902  ?  398 PRO B C   1 
ATOM   7016 O  O   . PRO B 1 398 ? 53.13021  -7.84434  -37.83696 1.000 28.66884  ?  398 PRO B O   1 
ATOM   7017 C  CB  . PRO B 1 398 ? 51.06920  -7.94463  -35.09854 1.000 23.03203  ?  398 PRO B CB  1 
ATOM   7018 C  CG  . PRO B 1 398 ? 49.71977  -8.43084  -34.65696 1.000 27.79885  ?  398 PRO B CG  1 
ATOM   7019 C  CD  . PRO B 1 398 ? 49.36521  -9.53071  -35.59830 1.000 22.47311  ?  398 PRO B CD  1 
ATOM   7020 N  N   . ARG B 1 399 ? 52.85968  -9.80835  -36.75787 1.000 27.01939  ?  399 ARG B N   1 
ATOM   7021 C  CA  . ARG B 1 399 ? 54.18583  -10.28111 -37.14466 1.000 24.19657  ?  399 ARG B CA  1 
ATOM   7022 C  C   . ARG B 1 399 ? 54.31136  -10.39651 -38.65758 1.000 24.95014  ?  399 ARG B C   1 
ATOM   7023 O  O   . ARG B 1 399 ? 55.38363  -10.14261 -39.21733 1.000 27.86098  ?  399 ARG B O   1 
ATOM   7024 C  CB  . ARG B 1 399 ? 54.48926  -11.62199 -36.47636 1.000 28.22564  ?  399 ARG B CB  1 
ATOM   7025 C  CG  . ARG B 1 399 ? 55.84992  -12.20924 -36.83924 1.000 35.59665  ?  399 ARG B CG  1 
ATOM   7026 C  CD  . ARG B 1 399 ? 56.99809  -11.36801 -36.29232 1.000 34.63832  ?  399 ARG B CD  1 
ATOM   7027 N  NE  . ARG B 1 399 ? 58.29903  -11.89548 -36.69058 1.000 36.66368  ?  399 ARG B NE  1 
ATOM   7028 C  CZ  . ARG B 1 399 ? 59.10744  -11.32140 -37.57197 1.000 39.22063  ?  399 ARG B CZ  1 
ATOM   7029 N  NH1 . ARG B 1 399 ? 58.79862  -10.17081 -38.14785 1.000 34.97805  ?  399 ARG B NH1 1 
ATOM   7030 N  NH2 . ARG B 1 399 ? 60.25822  -11.91375 -37.87852 1.000 36.17371  ?  399 ARG B NH2 1 
ATOM   7031 N  N   . PHE B 1 400 ? 53.22801  -10.78004 -39.33831 1.000 24.52132  ?  400 PHE B N   1 
ATOM   7032 C  CA  . PHE B 1 400 ? 53.25594  -10.80554 -40.79734 1.000 25.37277  ?  400 PHE B CA  1 
ATOM   7033 C  C   . PHE B 1 400 ? 53.52667  -9.41441  -41.35696 1.000 28.13083  ?  400 PHE B C   1 
ATOM   7034 O  O   . PHE B 1 400 ? 54.34518  -9.25102  -42.27090 1.000 25.22145  ?  400 PHE B O   1 
ATOM   7035 C  CB  . PHE B 1 400 ? 51.93725  -11.35432 -41.34984 1.000 21.81179  ?  400 PHE B CB  1 
ATOM   7036 C  CG  . PHE B 1 400 ? 51.69108  -12.80884 -41.03584 1.000 24.88346  ?  400 PHE B CG  1 
ATOM   7037 C  CD1 . PHE B 1 400 ? 52.66688  -13.58735 -40.43418 1.000 27.40540  ?  400 PHE B CD1 1 
ATOM   7038 C  CD2 . PHE B 1 400 ? 50.47992  -13.40021 -41.35990 1.000 23.48414  ?  400 PHE B CD2 1 
ATOM   7039 C  CE1 . PHE B 1 400 ? 52.43278  -14.92200 -40.15107 1.000 27.89943  ?  400 PHE B CE1 1 
ATOM   7040 C  CE2 . PHE B 1 400 ? 50.24077  -14.73330 -41.07879 1.000 21.88345  ?  400 PHE B CE2 1 
ATOM   7041 C  CZ  . PHE B 1 400 ? 51.21838  -15.49473 -40.47436 1.000 21.61593  ?  400 PHE B CZ  1 
ATOM   7042 N  N   . THR B 1 401 ? 52.85797  -8.39743  -40.80547 1.000 31.57338  ?  401 THR B N   1 
ATOM   7043 C  CA  . THR B 1 401 ? 53.07437  -7.02537  -41.25364 1.000 24.78420  ?  401 THR B CA  1 
ATOM   7044 C  C   . THR B 1 401 ? 54.51737  -6.59690  -41.02295 1.000 24.91887  ?  401 THR B C   1 
ATOM   7045 O  O   . THR B 1 401 ? 55.15555  -6.01737  -41.90982 1.000 29.00738  ?  401 THR B O   1 
ATOM   7046 C  CB  . THR B 1 401 ? 52.11614  -6.07893  -40.52657 1.000 18.34237  ?  401 THR B CB  1 
ATOM   7047 O  OG1 . THR B 1 401 ? 50.78424  -6.60259  -40.58319 1.000 16.58803  ?  401 THR B OG1 1 
ATOM   7048 C  CG2 . THR B 1 401 ? 52.13530  -4.70103  -41.17071 1.000 27.57201  ?  401 THR B CG2 1 
ATOM   7049 N  N   . GLU B 1 402 ? 55.05256  -6.88888  -39.83492 1.000 23.98993  ?  402 GLU B N   1 
ATOM   7050 C  CA  . GLU B 1 402 ? 56.42231  -6.49237  -39.51858 1.000 25.45202  ?  402 GLU B CA  1 
ATOM   7051 C  C   . GLU B 1 402 ? 57.42427  -7.18000  -40.43867 1.000 28.68999  ?  402 GLU B C   1 
ATOM   7052 O  O   . GLU B 1 402 ? 58.35138  -6.54376  -40.95435 1.000 26.43347  ?  402 GLU B O   1 
ATOM   7053 C  CB  . GLU B 1 402 ? 56.73565  -6.81220  -38.05763 1.000 27.75292  ?  402 GLU B CB  1 
ATOM   7054 C  CG  . GLU B 1 402 ? 55.83753  -6.11754  -37.05461 1.000 30.40155  ?  402 GLU B CG  1 
ATOM   7055 C  CD  . GLU B 1 402 ? 56.05852  -6.62442  -35.64554 1.000 32.97423  ?  402 GLU B CD  1 
ATOM   7056 O  OE1 . GLU B 1 402 ? 56.78313  -7.62984  -35.48478 1.000 31.75124  ?  402 GLU B OE1 1 
ATOM   7057 O  OE2 . GLU B 1 402 ? 55.50868  -6.02184  -34.69990 1.000 33.99875  -1 402 GLU B OE2 1 
ATOM   7058 N  N   . LEU B 1 403 ? 57.25453  -8.48728  -40.65275 1.000 33.48577  ?  403 LEU B N   1 
ATOM   7059 C  CA  . LEU B 1 403 ? 58.19115  -9.23271  -41.48592 1.000 28.77575  ?  403 LEU B CA  1 
ATOM   7060 C  C   . LEU B 1 403 ? 58.12465  -8.77764  -42.93697 1.000 26.67827  ?  403 LEU B C   1 
ATOM   7061 O  O   . LEU B 1 403 ? 59.15972  -8.66058  -43.60388 1.000 31.64666  ?  403 LEU B O   1 
ATOM   7062 C  CB  . LEU B 1 403 ? 57.91045  -10.73033 -41.37799 1.000 20.64317  ?  403 LEU B CB  1 
ATOM   7063 C  CG  . LEU B 1 403 ? 58.88622  -11.63708 -42.12654 1.000 28.06847  ?  403 LEU B CG  1 
ATOM   7064 C  CD1 . LEU B 1 403 ? 60.31473  -11.35094 -41.69065 1.000 42.02493  ?  403 LEU B CD1 1 
ATOM   7065 C  CD2 . LEU B 1 403 ? 58.53696  -13.09838 -41.90297 1.000 25.40450  ?  403 LEU B CD2 1 
ATOM   7066 N  N   . ALA B 1 404 ? 56.91745  -8.52134  -43.44710 1.000 27.08383  ?  404 ALA B N   1 
ATOM   7067 C  CA  . ALA B 1 404 ? 56.79053  -8.01930  -44.80955 1.000 27.08181  ?  404 ALA B CA  1 
ATOM   7068 C  C   . ALA B 1 404 ? 57.40348  -6.63136  -44.94175 1.000 31.78035  ?  404 ALA B C   1 
ATOM   7069 O  O   . ALA B 1 404 ? 58.00371  -6.30493  -45.97251 1.000 28.87648  ?  404 ALA B O   1 
ATOM   7070 C  CB  . ALA B 1 404 ? 55.32152  -8.00688  -45.22803 1.000 22.67914  ?  404 ALA B CB  1 
ATOM   7071 N  N   . LYS B 1 405 ? 57.25604  -5.79551  -43.90987 1.000 30.27233  ?  405 LYS B N   1 
ATOM   7072 C  CA  . LYS B 1 405 ? 57.87472  -4.47514  -43.93631 1.000 27.37955  ?  405 LYS B CA  1 
ATOM   7073 C  C   . LYS B 1 405 ? 59.39453  -4.57983  -43.95381 1.000 29.80100  ?  405 LYS B C   1 
ATOM   7074 O  O   . LYS B 1 405 ? 60.06708  -3.84376  -44.68578 1.000 32.43417  ?  405 LYS B O   1 
ATOM   7075 C  CB  . LYS B 1 405 ? 57.40097  -3.65767  -42.73572 1.000 27.91705  ?  405 LYS B CB  1 
ATOM   7076 C  CG  . LYS B 1 405 ? 57.77285  -2.19088  -42.79131 1.000 25.77739  ?  405 LYS B CG  1 
ATOM   7077 C  CD  . LYS B 1 405 ? 56.94705  -1.39659  -41.79662 1.000 29.54044  ?  405 LYS B CD  1 
ATOM   7078 C  CE  . LYS B 1 405 ? 56.96047  0.08479   -42.12276 1.000 22.12293  ?  405 LYS B CE  1 
ATOM   7079 N  NZ  . LYS B 1 405 ? 55.88876  0.81088   -41.38999 1.000 20.08335  ?  405 LYS B NZ  1 
ATOM   7080 N  N   . GLU B 1 406 ? 59.95350  -5.48800  -43.15007 1.000 31.59169  ?  406 GLU B N   1 
ATOM   7081 C  CA  . GLU B 1 406 ? 61.40077  -5.68733  -43.14910 1.000 27.84564  ?  406 GLU B CA  1 
ATOM   7082 C  C   . GLU B 1 406 ? 61.88542  -6.18588  -44.50486 1.000 27.00720  ?  406 GLU B C   1 
ATOM   7083 O  O   . GLU B 1 406 ? 62.86023  -5.66636  -45.06057 1.000 26.05599  ?  406 GLU B O   1 
ATOM   7084 C  CB  . GLU B 1 406 ? 61.79904  -6.67278  -42.05013 1.000 23.97818  ?  406 GLU B CB  1 
ATOM   7085 C  CG  . GLU B 1 406 ? 61.46160  -6.22624  -40.64248 1.000 30.57849  ?  406 GLU B CG  1 
ATOM   7086 C  CD  . GLU B 1 406 ? 61.59133  -7.35408  -39.63799 1.000 61.56408  ?  406 GLU B CD  1 
ATOM   7087 O  OE1 . GLU B 1 406 ? 62.17560  -8.40052  -39.99226 1.000 58.31733  ?  406 GLU B OE1 1 
ATOM   7088 O  OE2 . GLU B 1 406 ? 61.10317  -7.19873  -38.49858 1.000 75.30270  -1 406 GLU B OE2 1 
ATOM   7089 N  N   . ASN B 1 407 ? 61.20618  -7.19276  -45.05808 1.000 28.43618  ?  407 ASN B N   1 
ATOM   7090 C  CA  . ASN B 1 407 ? 61.60600  -7.77182  -46.33418 1.000 24.25305  ?  407 ASN B CA  1 
ATOM   7091 C  C   . ASN B 1 407 ? 61.30602  -6.86392  -47.51946 1.000 28.93769  ?  407 ASN B C   1 
ATOM   7092 O  O   . ASN B 1 407 ? 61.74222  -7.17045  -48.63439 1.000 29.80535  ?  407 ASN B O   1 
ATOM   7093 C  CB  . ASN B 1 407 ? 60.92101  -9.12608  -46.53216 1.000 37.70002  ?  407 ASN B CB  1 
ATOM   7094 C  CG  . ASN B 1 407 ? 61.46000  -10.19533 -45.59840 1.000 29.49948  ?  407 ASN B CG  1 
ATOM   7095 O  OD1 . ASN B 1 407 ? 62.62574  -10.16062 -45.20595 1.000 26.89614  ?  407 ASN B OD1 1 
ATOM   7096 N  ND2 . ASN B 1 407 ? 60.61246  -11.15482 -45.24200 1.000 28.66002  ?  407 ASN B ND2 1 
ATOM   7097 N  N   . GLY B 1 408 ? 60.57568  -5.76997  -47.31384 1.000 30.07247  ?  408 GLY B N   1 
ATOM   7098 C  CA  . GLY B 1 408 ? 60.27850  -4.85533  -48.39728 1.000 28.05514  ?  408 GLY B CA  1 
ATOM   7099 C  C   . GLY B 1 408 ? 59.16537  -5.29207  -49.31875 1.000 29.46907  ?  408 GLY B C   1 
ATOM   7100 O  O   . GLY B 1 408 ? 59.05517  -4.76553  -50.43062 1.000 25.25877  ?  408 GLY B O   1 
ATOM   7101 N  N   . VAL B 1 409 ? 58.33348  -6.23921  -48.89447 1.000 26.68892  ?  409 VAL B N   1 
ATOM   7102 C  CA  . VAL B 1 409 ? 57.24257  -6.73778  -49.72559 1.000 24.30866  ?  409 VAL B CA  1 
ATOM   7103 C  C   . VAL B 1 409 ? 56.11766  -5.70801  -49.70370 1.000 25.41793  ?  409 VAL B C   1 
ATOM   7104 O  O   . VAL B 1 409 ? 55.43123  -5.54356  -48.69241 1.000 25.96275  ?  409 VAL B O   1 
ATOM   7105 C  CB  . VAL B 1 409 ? 56.75069  -8.10693  -49.24536 1.000 20.78671  ?  409 VAL B CB  1 
ATOM   7106 C  CG1 . VAL B 1 409 ? 55.67691  -8.63953  -50.17927 1.000 21.54890  ?  409 VAL B CG1 1 
ATOM   7107 C  CG2 . VAL B 1 409 ? 57.91322  -9.08132  -49.14702 1.000 19.15531  ?  409 VAL B CG2 1 
ATOM   7108 N  N   . ALA B 1 410 ? 55.92664  -5.01509  -50.82215 1.000 25.31018  ?  410 ALA B N   1 
ATOM   7109 C  CA  . ALA B 1 410 ? 54.87634  -4.01681  -50.92035 1.000 24.04804  ?  410 ALA B CA  1 
ATOM   7110 C  C   . ALA B 1 410 ? 53.52050  -4.68547  -51.11379 1.000 23.03775  ?  410 ALA B C   1 
ATOM   7111 O  O   . ALA B 1 410 ? 53.42027  -5.86847  -51.44994 1.000 25.44605  ?  410 ALA B O   1 
ATOM   7112 C  CB  . ALA B 1 410 ? 55.15115  -3.04944  -52.07188 1.000 25.86331  ?  410 ALA B CB  1 
ATOM   7113 N  N   . VAL B 1 411 ? 52.46570  -3.90606  -50.89941 1.000 22.86831  ?  411 VAL B N   1 
ATOM   7114 C  CA  . VAL B 1 411 ? 51.09649  -4.38233  -51.03901 1.000 21.14206  ?  411 VAL B CA  1 
ATOM   7115 C  C   . VAL B 1 411 ? 50.41457  -3.59894  -52.15063 1.000 21.84435  ?  411 VAL B C   1 
ATOM   7116 O  O   . VAL B 1 411 ? 50.44463  -2.36231  -52.15810 1.000 22.92947  ?  411 VAL B O   1 
ATOM   7117 C  CB  . VAL B 1 411 ? 50.30526  -4.25565  -49.72642 1.000 15.33975  ?  411 VAL B CB  1 
ATOM   7118 C  CG1 . VAL B 1 411 ? 48.84385  -4.48192  -50.00220 1.000 15.70690  ?  411 VAL B CG1 1 
ATOM   7119 C  CG2 . VAL B 1 411 ? 50.80196  -5.26184  -48.70579 1.000 14.02683  ?  411 VAL B CG2 1 
ATOM   7120 N  N   . GLU B 1 412 ? 49.79105  -4.32182  -53.07746 1.000 20.53995  ?  412 GLU B N   1 
ATOM   7121 C  CA  . GLU B 1 412 ? 49.03829  -3.72280  -54.17604 1.000 23.08328  ?  412 GLU B CA  1 
ATOM   7122 C  C   . GLU B 1 412 ? 47.60299  -3.51146  -53.70940 1.000 21.61401  ?  412 GLU B C   1 
ATOM   7123 O  O   . GLU B 1 412 ? 46.80422  -4.45055  -53.66858 1.000 19.94970  ?  412 GLU B O   1 
ATOM   7124 C  CB  . GLU B 1 412 ? 49.10461  -4.61220  -55.41147 1.000 23.89496  ?  412 GLU B CB  1 
ATOM   7125 C  CG  . GLU B 1 412 ? 50.51724  -4.85511  -55.91635 1.000 27.22465  ?  412 GLU B CG  1 
ATOM   7126 C  CD  . GLU B 1 412 ? 50.61269  -6.07208  -56.81439 1.000 29.42766  ?  412 GLU B CD  1 
ATOM   7127 O  OE1 . GLU B 1 412 ? 49.95255  -7.08803  -56.51025 1.000 26.53826  ?  412 GLU B OE1 1 
ATOM   7128 O  OE2 . GLU B 1 412 ? 51.34420  -6.01223  -57.82495 1.000 28.06168  -1 412 GLU B OE2 1 
ATOM   7129 N  N   . VAL B 1 413 ? 47.27451  -2.27277  -53.35780 1.000 17.68295  ?  413 VAL B N   1 
ATOM   7130 C  CA  . VAL B 1 413 ? 45.94376  -1.92252  -52.87804 1.000 19.36098  ?  413 VAL B CA  1 
ATOM   7131 C  C   . VAL B 1 413 ? 45.08683  -1.51512  -54.06980 1.000 25.04549  ?  413 VAL B C   1 
ATOM   7132 O  O   . VAL B 1 413 ? 45.44651  -0.60533  -54.82562 1.000 23.39608  ?  413 VAL B O   1 
ATOM   7133 C  CB  . VAL B 1 413 ? 46.00650  -0.79761  -51.83503 1.000 17.50310  ?  413 VAL B CB  1 
ATOM   7134 C  CG1 . VAL B 1 413 ? 44.61845  -0.51658  -51.27683 1.000 22.18361  ?  413 VAL B CG1 1 
ATOM   7135 C  CG2 . VAL B 1 413 ? 46.97523  -1.16103  -50.72124 1.000 17.42721  ?  413 VAL B CG2 1 
ATOM   7136 N  N   . ASN B 1 414 ? 43.95061  -2.19515  -54.23726 1.000 25.34026  ?  414 ASN B N   1 
ATOM   7137 C  CA  . ASN B 1 414 ? 42.97400  -1.90307  -55.28502 1.000 22.92350  ?  414 ASN B CA  1 
ATOM   7138 C  C   . ASN B 1 414 ? 41.66499  -1.55308  -54.58862 1.000 26.01458  ?  414 ASN B C   1 
ATOM   7139 O  O   . ASN B 1 414 ? 40.84507  -2.44129  -54.30480 1.000 26.66236  ?  414 ASN B O   1 
ATOM   7140 C  CB  . ASN B 1 414 ? 42.80181  -3.08892  -56.23365 1.000 22.82387  ?  414 ASN B CB  1 
ATOM   7141 C  CG  . ASN B 1 414 ? 44.12342  -3.62495  -56.74654 1.000 22.18311  ?  414 ASN B CG  1 
ATOM   7142 O  OD1 . ASN B 1 414 ? 44.64081  -3.16396  -57.76259 1.000 21.58173  ?  414 ASN B OD1 1 
ATOM   7143 N  ND2 . ASN B 1 414 ? 44.67375  -4.61064  -56.04677 1.000 21.85525  ?  414 ASN B ND2 1 
ATOM   7144 N  N   . PRO B 1 415 ? 41.42232  -0.26982  -54.30537 1.000 21.29234  ?  415 PRO B N   1 
ATOM   7145 C  CA  . PRO B 1 415 ? 40.29938  0.11508   -53.43573 1.000 16.87937  ?  415 PRO B CA  1 
ATOM   7146 C  C   . PRO B 1 415 ? 38.93000  -0.22044  -54.00187 1.000 17.90269  ?  415 PRO B C   1 
ATOM   7147 O  O   . PRO B 1 415 ? 38.09311  -0.83552  -53.32811 1.000 23.54538  ?  415 PRO B O   1 
ATOM   7148 C  CB  . PRO B 1 415 ? 40.47262  1.63349   -53.30565 1.000 16.65209  ?  415 PRO B CB  1 
ATOM   7149 C  CG  . PRO B 1 415 ? 41.90675  1.88828   -53.65805 1.000 18.46297  ?  415 PRO B CG  1 
ATOM   7150 C  CD  . PRO B 1 415 ? 42.22193  0.89288   -54.71767 1.000 12.40973  ?  415 PRO B CD  1 
ATOM   7151 N  N   . ILE B 1 416 ? 38.69291  0.19518   -55.24699 1.000 15.08072  ?  416 ILE B N   1 
ATOM   7152 C  CA  . ILE B 1 416 ? 37.38367  -0.01477  -55.85697 1.000 16.16788  ?  416 ILE B CA  1 
ATOM   7153 C  C   . ILE B 1 416 ? 37.09909  -1.50326  -56.00610 1.000 21.82687  ?  416 ILE B C   1 
ATOM   7154 O  O   . ILE B 1 416 ? 35.96275  -1.95446  -55.81329 1.000 19.96750  ?  416 ILE B O   1 
ATOM   7155 C  CB  . ILE B 1 416 ? 37.29141  0.71909   -57.20715 1.000 21.54574  ?  416 ILE B CB  1 
ATOM   7156 C  CG1 . ILE B 1 416 ? 37.70124  2.18502   -57.05318 1.000 20.28999  ?  416 ILE B CG1 1 
ATOM   7157 C  CG2 . ILE B 1 416 ? 35.88071  0.62779   -57.75797 1.000 19.00952  ?  416 ILE B CG2 1 
ATOM   7158 C  CD1 . ILE B 1 416 ? 37.65202  2.96898   -58.35227 1.000 22.23518  ?  416 ILE B CD1 1 
ATOM   7159 N  N   . SER B 1 417 ? 38.12312  -2.29063  -56.35012 1.000 25.02797  ?  417 SER B N   1 
ATOM   7160 C  CA  . SER B 1 417 ? 37.93233  -3.73359  -56.46663 1.000 20.28099  ?  417 SER B CA  1 
ATOM   7161 C  C   . SER B 1 417 ? 37.55149  -4.34454  -55.12607 1.000 16.23243  ?  417 SER B C   1 
ATOM   7162 O  O   . SER B 1 417 ? 36.66825  -5.20673  -55.05715 1.000 16.51739  ?  417 SER B O   1 
ATOM   7163 C  CB  . SER B 1 417 ? 39.19602  -4.39926  -57.01291 1.000 19.96820  ?  417 SER B CB  1 
ATOM   7164 O  OG  . SER B 1 417 ? 40.09590  -4.73028  -55.97147 1.000 25.28344  ?  417 SER B OG  1 
ATOM   7165 N  N   . ASN B 1 418 ? 38.20716  -3.90829  -54.04747 1.000 18.82919  ?  418 ASN B N   1 
ATOM   7166 C  CA  . ASN B 1 418 ? 37.87807  -4.42811  -52.72651 1.000 19.13775  ?  418 ASN B CA  1 
ATOM   7167 C  C   . ASN B 1 418 ? 36.47363  -4.02388  -52.30305 1.000 18.49695  ?  418 ASN B C   1 
ATOM   7168 O  O   . ASN B 1 418 ? 35.79536  -4.78848  -51.60788 1.000 18.63251  ?  418 ASN B O   1 
ATOM   7169 C  CB  . ASN B 1 418 ? 38.90418  -3.95321  -51.69754 1.000 13.41324  ?  418 ASN B CB  1 
ATOM   7170 C  CG  . ASN B 1 418 ? 40.31583  -4.38366  -52.04213 1.000 21.22030  ?  418 ASN B CG  1 
ATOM   7171 O  OD1 . ASN B 1 418 ? 41.27642  -3.66000  -51.78496 1.000 22.07334  ?  418 ASN B OD1 1 
ATOM   7172 N  ND2 . ASN B 1 418 ? 40.44741  -5.56378  -52.63804 1.000 25.36266  ?  418 ASN B ND2 1 
ATOM   7173 N  N   . GLN B 1 419 ? 36.01886  -2.83419  -52.70252 1.000 20.91647  ?  419 GLN B N   1 
ATOM   7174 C  CA  . GLN B 1 419 ? 34.65138  -2.44067  -52.37714 1.000 22.23435  ?  419 GLN B CA  1 
ATOM   7175 C  C   . GLN B 1 419 ? 33.63604  -3.26699  -53.15828 1.000 26.82705  ?  419 GLN B C   1 
ATOM   7176 O  O   . GLN B 1 419 ? 32.69316  -3.82030  -52.57967 1.000 25.60616  ?  419 GLN B O   1 
ATOM   7177 C  CB  . GLN B 1 419 ? 34.44064  -0.95279  -52.65143 1.000 16.42416  ?  419 GLN B CB  1 
ATOM   7178 C  CG  . GLN B 1 419 ? 33.01486  -0.49968  -52.37251 1.000 15.27193  ?  419 GLN B CG  1 
ATOM   7179 C  CD  . GLN B 1 419 ? 32.74900  0.92435   -52.80916 1.000 19.38976  ?  419 GLN B CD  1 
ATOM   7180 O  OE1 . GLN B 1 419 ? 32.94575  1.27887   -53.97153 1.000 18.20855  ?  419 GLN B OE1 1 
ATOM   7181 N  NE2 . GLN B 1 419 ? 32.29660  1.75154   -51.87542 1.000 23.77621  ?  419 GLN B NE2 1 
ATOM   7182 N  N   . ILE B 1 420 ? 33.82026  -3.37001  -54.47622 1.000 24.14507  ?  420 ILE B N   1 
ATOM   7183 C  CA  . ILE B 1 420 ? 32.80735  -3.99000  -55.32552 1.000 20.18906  ?  420 ILE B CA  1 
ATOM   7184 C  C   . ILE B 1 420 ? 32.72314  -5.48856  -55.06577 1.000 25.05229  ?  420 ILE B C   1 
ATOM   7185 O  O   . ILE B 1 420 ? 31.62707  -6.05292  -54.96156 1.000 21.96320  ?  420 ILE B O   1 
ATOM   7186 C  CB  . ILE B 1 420 ? 33.09684  -3.68312  -56.80573 1.000 15.18514  ?  420 ILE B CB  1 
ATOM   7187 C  CG1 . ILE B 1 420 ? 32.95256  -2.18364  -57.07097 1.000 13.64355  ?  420 ILE B CG1 1 
ATOM   7188 C  CG2 . ILE B 1 420 ? 32.17310  -4.48334  -57.71344 1.000 16.42747  ?  420 ILE B CG2 1 
ATOM   7189 C  CD1 . ILE B 1 420 ? 33.19133  -1.79397  -58.50916 1.000 16.61723  ?  420 ILE B CD1 1 
ATOM   7190 N  N   . LEU B 1 421 ? 33.86878  -6.15396  -54.94182 1.000 24.48845  ?  421 LEU B N   1 
ATOM   7191 C  CA  . LEU B 1 421 ? 33.90149  -7.60073  -54.77472 1.000 16.65400  ?  421 LEU B CA  1 
ATOM   7192 C  C   . LEU B 1 421 ? 33.55969  -8.04975  -53.35740 1.000 20.03000  ?  421 LEU B C   1 
ATOM   7193 O  O   . LEU B 1 421 ? 33.77063  -9.22233  -53.03010 1.000 24.13961  ?  421 LEU B O   1 
ATOM   7194 C  CB  . LEU B 1 421 ? 35.27094  -8.14476  -55.18890 1.000 16.74586  ?  421 LEU B CB  1 
ATOM   7195 C  CG  . LEU B 1 421 ? 35.58969  -7.96173  -56.67590 1.000 17.47612  ?  421 LEU B CG  1 
ATOM   7196 C  CD1 . LEU B 1 421 ? 36.89056  -8.65632  -57.05177 1.000 14.74269  ?  421 LEU B CD1 1 
ATOM   7197 C  CD2 . LEU B 1 421 ? 34.43785  -8.46345  -57.53815 1.000 18.59658  ?  421 LEU B CD2 1 
ATOM   7198 N  N   . GLY B 1 422 ? 33.05174  -7.15507  -52.51450 1.000 21.95277  ?  422 GLY B N   1 
ATOM   7199 C  CA  . GLY B 1 422 ? 32.42981  -7.54195  -51.26582 1.000 21.74807  ?  422 GLY B CA  1 
ATOM   7200 C  C   . GLY B 1 422 ? 33.29973  -7.53139  -50.02882 1.000 18.98392  ?  422 GLY B C   1 
ATOM   7201 O  O   . GLY B 1 422 ? 32.82655  -7.95082  -48.96626 1.000 18.41643  ?  422 GLY B O   1 
ATOM   7202 N  N   . LEU B 1 423 ? 34.55104  -7.07582  -50.12214 1.000 20.11864  ?  423 LEU B N   1 
ATOM   7203 C  CA  . LEU B 1 423 ? 35.39070  -7.02118  -48.92803 1.000 16.65441  ?  423 LEU B CA  1 
ATOM   7204 C  C   . LEU B 1 423 ? 34.98207  -5.87766  -48.00741 1.000 17.17278  ?  423 LEU B C   1 
ATOM   7205 O  O   . LEU B 1 423 ? 34.92650  -6.04950  -46.78438 1.000 14.68087  ?  423 LEU B O   1 
ATOM   7206 C  CB  . LEU B 1 423 ? 36.86229  -6.88693  -49.31544 1.000 14.64446  ?  423 LEU B CB  1 
ATOM   7207 C  CG  . LEU B 1 423 ? 37.55349  -8.13406  -49.86043 1.000 13.74334  ?  423 LEU B CG  1 
ATOM   7208 C  CD1 . LEU B 1 423 ? 39.05147  -7.90376  -49.90759 1.000 15.41356  ?  423 LEU B CD1 1 
ATOM   7209 C  CD2 . LEU B 1 423 ? 37.21763  -9.35410  -49.01768 1.000 18.14911  ?  423 LEU B CD2 1 
ATOM   7210 N  N   . VAL B 1 424 ? 34.69956  -4.70279  -48.57348 1.000 21.79067  ?  424 VAL B N   1 
ATOM   7211 C  CA  . VAL B 1 424 ? 34.36572  -3.51541  -47.79922 1.000 18.43766  ?  424 VAL B CA  1 
ATOM   7212 C  C   . VAL B 1 424 ? 33.21763  -2.78945  -48.48942 1.000 20.40939  ?  424 VAL B C   1 
ATOM   7213 O  O   . VAL B 1 424 ? 32.94770  -2.98872  -49.67587 1.000 23.13209  ?  424 VAL B O   1 
ATOM   7214 C  CB  . VAL B 1 424 ? 35.58733  -2.57902  -47.62920 1.000 12.02229  ?  424 VAL B CB  1 
ATOM   7215 C  CG1 . VAL B 1 424 ? 35.80307  -1.73833  -48.87901 1.000 15.02161  ?  424 VAL B CG1 1 
ATOM   7216 C  CG2 . VAL B 1 424 ? 35.44139  -1.70617  -46.39077 1.000 11.44294  ?  424 VAL B CG2 1 
ATOM   7217 N  N   . ARG B 1 425 ? 32.52589  -1.94997  -47.72106 1.000 19.80816  ?  425 ARG B N   1 
ATOM   7218 C  CA  . ARG B 1 425 ? 31.44456  -1.12445  -48.24435 1.000 21.69558  ?  425 ARG B CA  1 
ATOM   7219 C  C   . ARG B 1 425 ? 31.75150  0.35966   -48.13465 1.000 22.40492  ?  425 ARG B C   1 
ATOM   7220 O  O   . ARG B 1 425 ? 31.59286  1.09626   -49.11500 1.000 18.90146  ?  425 ARG B O   1 
ATOM   7221 C  CB  . ARG B 1 425 ? 30.13065  -1.45064  -47.51504 1.000 27.69173  ?  425 ARG B CB  1 
ATOM   7222 C  CG  . ARG B 1 425 ? 28.89532  -0.83513  -48.15236 1.000 30.63689  ?  425 ARG B CG  1 
ATOM   7223 C  CD  . ARG B 1 425 ? 27.63221  -1.33556  -47.47787 1.000 41.24621  ?  425 ARG B CD  1 
ATOM   7224 N  NE  . ARG B 1 425 ? 26.41868  -0.78765  -48.07276 1.000 64.42039  ?  425 ARG B NE  1 
ATOM   7225 C  CZ  . ARG B 1 425 ? 25.60263  -1.46401  -48.86992 1.000 65.15341  ?  425 ARG B CZ  1 
ATOM   7226 N  NH1 . ARG B 1 425 ? 25.83576  -2.72746  -49.18723 1.000 56.47687  ?  425 ARG B NH1 1 
ATOM   7227 N  NH2 . ARG B 1 425 ? 24.52265  -0.85916  -49.35692 1.000 57.18132  ?  425 ARG B NH2 1 
ATOM   7228 N  N   . ASP B 1 426 ? 32.18841  0.82122   -46.96761 1.000 28.89622  ?  426 ASP B N   1 
ATOM   7229 C  CA  . ASP B 1 426 ? 32.66617  2.18669   -46.80054 1.000 18.91021  ?  426 ASP B CA  1 
ATOM   7230 C  C   . ASP B 1 426 ? 34.18083  2.17630   -46.96708 1.000 14.36317  ?  426 ASP B C   1 
ATOM   7231 O  O   . ASP B 1 426 ? 34.88973  1.54822   -46.17463 1.000 21.25233  ?  426 ASP B O   1 
ATOM   7232 C  CB  . ASP B 1 426 ? 32.25909  2.73403   -45.43166 1.000 15.60286  ?  426 ASP B CB  1 
ATOM   7233 C  CG  . ASP B 1 426 ? 32.43417  4.23873   -45.32084 1.000 25.53957  ?  426 ASP B CG  1 
ATOM   7234 O  OD1 . ASP B 1 426 ? 33.45441  4.76480   -45.81267 1.000 29.71510  ?  426 ASP B OD1 1 
ATOM   7235 O  OD2 . ASP B 1 426 ? 31.54649  4.89714   -44.73476 1.000 16.95910  -1 426 ASP B OD2 1 
ATOM   7236 N  N   . VAL B 1 427 ? 34.67413  2.85332   -48.00756 1.000 12.00204  ?  427 VAL B N   1 
ATOM   7237 C  CA  . VAL B 1 427 ? 36.10108  2.81445   -48.30363 1.000 13.60078  ?  427 VAL B CA  1 
ATOM   7238 C  C   . VAL B 1 427 ? 36.92833  3.45594   -47.19538 1.000 19.69272  ?  427 VAL B C   1 
ATOM   7239 O  O   . VAL B 1 427 ? 38.11198  3.12985   -47.04379 1.000 14.86304  ?  427 VAL B O   1 
ATOM   7240 C  CB  . VAL B 1 427 ? 36.38465  3.48149   -49.66247 1.000 16.08043  ?  427 VAL B CB  1 
ATOM   7241 C  CG1 . VAL B 1 427 ? 37.77479  3.10817   -50.15618 1.000 14.16091  ?  427 VAL B CG1 1 
ATOM   7242 C  CG2 . VAL B 1 427 ? 35.32830  3.07743   -50.67989 1.000 12.12552  ?  427 VAL B CG2 1 
ATOM   7243 N  N   . ARG B 1 428 ? 36.33731  4.35795   -46.40604 1.000 22.17471  ?  428 ARG B N   1 
ATOM   7244 C  CA  . ARG B 1 428 ? 37.04040  4.90269   -45.24996 1.000 20.80794  ?  428 ARG B CA  1 
ATOM   7245 C  C   . ARG B 1 428 ? 37.29380  3.84478   -44.18383 1.000 22.61050  ?  428 ARG B C   1 
ATOM   7246 O  O   . ARG B 1 428 ? 38.14981  4.04750   -43.31589 1.000 25.70844  ?  428 ARG B O   1 
ATOM   7247 C  CB  . ARG B 1 428 ? 36.25220  6.06558   -44.65056 1.000 15.17302  ?  428 ARG B CB  1 
ATOM   7248 C  CG  . ARG B 1 428 ? 36.01614  7.21334   -45.60999 1.000 15.44423  ?  428 ARG B CG  1 
ATOM   7249 C  CD  . ARG B 1 428 ? 35.08210  8.23354   -44.99117 1.000 22.40182  ?  428 ARG B CD  1 
ATOM   7250 N  NE  . ARG B 1 428 ? 33.83352  7.61426   -44.56431 1.000 19.84821  ?  428 ARG B NE  1 
ATOM   7251 C  CZ  . ARG B 1 428 ? 32.84850  8.25468   -43.95102 1.000 17.00934  ?  428 ARG B CZ  1 
ATOM   7252 N  NH1 . ARG B 1 428 ? 32.93052  9.54525   -43.67301 1.000 19.62680  ?  428 ARG B NH1 1 
ATOM   7253 N  NH2 . ARG B 1 428 ? 31.75351  7.58293   -43.60783 1.000 20.36043  ?  428 ARG B NH2 1 
ATOM   7254 N  N   . ASN B 1 429 ? 36.56761  2.72815   -44.22867 1.000 19.56591  ?  429 ASN B N   1 
ATOM   7255 C  CA  . ASN B 1 429 ? 36.80728  1.58584   -43.36037 1.000 16.52681  ?  429 ASN B CA  1 
ATOM   7256 C  C   . ASN B 1 429 ? 37.70590  0.54072   -44.00793 1.000 17.14359  ?  429 ASN B C   1 
ATOM   7257 O  O   . ASN B 1 429 ? 37.66155  -0.63103  -43.61549 1.000 21.91408  ?  429 ASN B O   1 
ATOM   7258 C  CB  . ASN B 1 429 ? 35.47998  0.94605   -42.94868 1.000 12.95846  ?  429 ASN B CB  1 
ATOM   7259 C  CG  . ASN B 1 429 ? 34.93032  1.52208   -41.66243 1.000 18.73888  ?  429 ASN B CG  1 
ATOM   7260 O  OD1 . ASN B 1 429 ? 35.41759  2.53655   -41.16310 1.000 29.35266  ?  429 ASN B OD1 1 
ATOM   7261 N  ND2 . ASN B 1 429 ? 33.90812  0.87559   -41.11647 1.000 15.20145  ?  429 ASN B ND2 1 
ATOM   7262 N  N   . HIS B 1 430 ? 38.50618  0.93287   -44.99495 1.000 16.34095  ?  430 HIS B N   1 
ATOM   7263 C  CA  . HIS B 1 430 ? 39.41347  -0.00625  -45.63680 1.000 17.68550  ?  430 HIS B CA  1 
ATOM   7264 C  C   . HIS B 1 430 ? 40.48418  -0.45751  -44.65136 1.000 24.77488  ?  430 HIS B C   1 
ATOM   7265 O  O   . HIS B 1 430 ? 40.96208  0.32490   -43.82447 1.000 30.33154  ?  430 HIS B O   1 
ATOM   7266 C  CB  . HIS B 1 430 ? 40.05486  0.63269   -46.86639 1.000 18.95878  ?  430 HIS B CB  1 
ATOM   7267 C  CG  . HIS B 1 430 ? 40.68251  -0.35039  -47.80387 1.000 19.85166  ?  430 HIS B CG  1 
ATOM   7268 N  ND1 . HIS B 1 430 ? 42.03263  -0.62711  -47.79959 1.000 18.67979  ?  430 HIS B ND1 1 
ATOM   7269 C  CD2 . HIS B 1 430 ? 40.14557  -1.11295  -48.78519 1.000 18.53335  ?  430 HIS B CD2 1 
ATOM   7270 C  CE1 . HIS B 1 430 ? 42.29909  -1.52111  -48.73473 1.000 17.71976  ?  430 HIS B CE1 1 
ATOM   7271 N  NE2 . HIS B 1 430 ? 41.17180  -1.83244  -49.34739 1.000 19.76322  ?  430 HIS B NE2 1 
ATOM   7272 N  N   . ALA B 1 431 ? 40.86538  -1.73248  -44.74937 1.000 21.28393  ?  431 ALA B N   1 
ATOM   7273 C  CA  . ALA B 1 431 ? 41.73893  -2.32291  -43.74115 1.000 21.95848  ?  431 ALA B CA  1 
ATOM   7274 C  C   . ALA B 1 431 ? 43.15522  -1.76823  -43.80579 1.000 20.26472  ?  431 ALA B C   1 
ATOM   7275 O  O   . ALA B 1 431 ? 43.85440  -1.74603  -42.78702 1.000 26.02605  ?  431 ALA B O   1 
ATOM   7276 C  CB  . ALA B 1 431 ? 41.76368  -3.84205  -43.89295 1.000 22.55876  ?  431 ALA B CB  1 
ATOM   7277 N  N   . LEU B 1 432 ? 43.59826  -1.32095  -44.97459 1.000 18.46749  ?  432 LEU B N   1 
ATOM   7278 C  CA  . LEU B 1 432 ? 44.97954  -0.89522  -45.14413 1.000 28.11629  ?  432 LEU B CA  1 
ATOM   7279 C  C   . LEU B 1 432 ? 45.18301  0.59837   -44.92529 1.000 22.95216  ?  432 LEU B C   1 
ATOM   7280 O  O   . LEU B 1 432 ? 46.29776  1.09078   -45.12654 1.000 20.20020  ?  432 LEU B O   1 
ATOM   7281 C  CB  . LEU B 1 432 ? 45.47819  -1.30123  -46.53076 1.000 23.56517  ?  432 LEU B CB  1 
ATOM   7282 C  CG  . LEU B 1 432 ? 45.67564  -2.81457  -46.65892 1.000 26.13193  ?  432 LEU B CG  1 
ATOM   7283 C  CD1 . LEU B 1 432 ? 44.46053  -3.53174  -47.23876 1.000 30.25002  ?  432 LEU B CD1 1 
ATOM   7284 C  CD2 . LEU B 1 432 ? 46.89866  -3.08788  -47.49276 1.000 21.78042  ?  432 LEU B CD2 1 
ATOM   7285 N  N   . VAL B 1 433 ? 44.14031  1.32611   -44.52099 1.000 17.82754  ?  433 VAL B N   1 
ATOM   7286 C  CA  . VAL B 1 433 ? 44.31194  2.73874   -44.17648 1.000 16.79579  ?  433 VAL B CA  1 
ATOM   7287 C  C   . VAL B 1 433 ? 45.28638  2.93132   -43.01888 1.000 14.15390  ?  433 VAL B C   1 
ATOM   7288 O  O   . VAL B 1 433 ? 46.18066  3.78770   -43.13025 1.000 16.69913  ?  433 VAL B O   1 
ATOM   7289 C  CB  . VAL B 1 433 ? 42.94049  3.38689   -43.90897 1.000 18.05346  ?  433 VAL B CB  1 
ATOM   7290 C  CG1 . VAL B 1 433 ? 43.10135  4.86615   -43.59935 1.000 20.49747  ?  433 VAL B CG1 1 
ATOM   7291 C  CG2 . VAL B 1 433 ? 42.01581  3.17951   -45.09222 1.000 18.46997  ?  433 VAL B CG2 1 
ATOM   7292 N  N   . PRO B 1 434 ? 45.17657  2.20838   -41.89477 1.000 16.49070  ?  434 PRO B N   1 
ATOM   7293 C  CA  . PRO B 1 434 ? 46.17179  2.39501   -40.82586 1.000 17.86634  ?  434 PRO B CA  1 
ATOM   7294 C  C   . PRO B 1 434 ? 47.58620  2.06346   -41.25812 1.000 17.37330  ?  434 PRO B C   1 
ATOM   7295 O  O   . PRO B 1 434 ? 48.53388  2.70531   -40.78765 1.000 16.68263  ?  434 PRO B O   1 
ATOM   7296 C  CB  . PRO B 1 434 ? 45.68273  1.44986   -39.71904 1.000 15.20255  ?  434 PRO B CB  1 
ATOM   7297 C  CG  . PRO B 1 434 ? 44.23837  1.25688   -39.99396 1.000 15.02758  ?  434 PRO B CG  1 
ATOM   7298 C  CD  . PRO B 1 434 ? 44.12816  1.25576   -41.48451 1.000 18.52441  ?  434 PRO B CD  1 
ATOM   7299 N  N   . LEU B 1 435 ? 47.76102  1.07729   -42.14102 1.000 15.44894  ?  435 LEU B N   1 
ATOM   7300 C  CA  . LEU B 1 435 ? 49.09634  0.77846   -42.64405 1.000 16.32147  ?  435 LEU B CA  1 
ATOM   7301 C  C   . LEU B 1 435 ? 49.61709  1.89928   -43.53302 1.000 17.42938  ?  435 LEU B C   1 
ATOM   7302 O  O   . LEU B 1 435 ? 50.82877  2.13860   -43.57726 1.000 21.88526  ?  435 LEU B O   1 
ATOM   7303 C  CB  . LEU B 1 435 ? 49.09414  -0.55534  -43.39028 1.000 23.14008  ?  435 LEU B CB  1 
ATOM   7304 C  CG  . LEU B 1 435 ? 48.80560  -1.77619  -42.51138 1.000 20.53581  ?  435 LEU B CG  1 
ATOM   7305 C  CD1 . LEU B 1 435 ? 48.90021  -3.06533  -43.31114 1.000 19.90463  ?  435 LEU B CD1 1 
ATOM   7306 C  CD2 . LEU B 1 435 ? 49.74861  -1.81252  -41.31729 1.000 17.28912  ?  435 LEU B CD2 1 
ATOM   7307 N  N   . ILE B 1 436 ? 48.72496  2.59330   -44.24497 1.000 20.28854  ?  436 ILE B N   1 
ATOM   7308 C  CA  . ILE B 1 436 ? 49.12361  3.81569   -44.93759 1.000 18.61730  ?  436 ILE B CA  1 
ATOM   7309 C  C   . ILE B 1 436 ? 49.58729  4.85806   -43.93161 1.000 17.29121  ?  436 ILE B C   1 
ATOM   7310 O  O   . ILE B 1 436 ? 50.62238  5.50918   -44.11776 1.000 16.90916  ?  436 ILE B O   1 
ATOM   7311 C  CB  . ILE B 1 436 ? 47.96649  4.35255   -45.80154 1.000 15.40809  ?  436 ILE B CB  1 
ATOM   7312 C  CG1 . ILE B 1 436 ? 47.61173  3.36637   -46.91309 1.000 14.34554  ?  436 ILE B CG1 1 
ATOM   7313 C  CG2 . ILE B 1 436 ? 48.32347  5.71181   -46.38532 1.000 19.00232  ?  436 ILE B CG2 1 
ATOM   7314 C  CD1 . ILE B 1 436 ? 46.49903  3.84930   -47.81579 1.000 13.71185  ?  436 ILE B CD1 1 
ATOM   7315 N  N   . ALA B 1 437 ? 48.83444  5.02112   -42.84189 1.000 16.74555  ?  437 ALA B N   1 
ATOM   7316 C  CA  . ALA B 1 437 ? 49.14633  6.03622   -41.84339 1.000 15.03095  ?  437 ALA B CA  1 
ATOM   7317 C  C   . ALA B 1 437 ? 50.40936  5.73081   -41.04687 1.000 23.50269  ?  437 ALA B C   1 
ATOM   7318 O  O   . ALA B 1 437 ? 50.88226  6.60928   -40.31757 1.000 27.80814  ?  437 ALA B O   1 
ATOM   7319 C  CB  . ALA B 1 437 ? 47.96602  6.20931   -40.88893 1.000 16.38207  ?  437 ALA B CB  1 
ATOM   7320 N  N   . ASP B 1 438 ? 50.95852  4.51895   -41.15052 1.000 24.53159  ?  438 ASP B N   1 
ATOM   7321 C  CA  . ASP B 1 438 ? 52.20972  4.17239   -40.48701 1.000 20.82939  ?  438 ASP B CA  1 
ATOM   7322 C  C   . ASP B 1 438 ? 53.33744  3.93021   -41.48573 1.000 20.63675  ?  438 ASP B C   1 
ATOM   7323 O  O   . ASP B 1 438 ? 54.32225  3.26168   -41.15637 1.000 28.33445  ?  438 ASP B O   1 
ATOM   7324 C  CB  . ASP B 1 438 ? 52.01880  2.95176   -39.58520 1.000 21.10646  ?  438 ASP B CB  1 
ATOM   7325 C  CG  . ASP B 1 438 ? 53.07272  2.86163   -38.49199 1.000 35.51265  ?  438 ASP B CG  1 
ATOM   7326 O  OD1 . ASP B 1 438 ? 53.91106  3.78311   -38.39293 1.000 37.44419  ?  438 ASP B OD1 1 
ATOM   7327 O  OD2 . ASP B 1 438 ? 53.06395  1.86974   -37.73238 1.000 51.67593  -1 438 ASP B OD2 1 
ATOM   7328 N  N   . ASP B 1 439 ? 53.20544  4.46234   -42.70160 1.000 19.04445  ?  439 ASP B N   1 
ATOM   7329 C  CA  . ASP B 1 439 ? 54.23211  4.37519   -43.73994 1.000 23.21716  ?  439 ASP B CA  1 
ATOM   7330 C  C   . ASP B 1 439 ? 54.58710  2.91855   -44.04809 1.000 29.01917  ?  439 ASP B C   1 
ATOM   7331 O  O   . ASP B 1 439 ? 55.72539  2.47355   -43.88764 1.000 38.88632  ?  439 ASP B O   1 
ATOM   7332 C  CB  . ASP B 1 439 ? 55.47850  5.17798   -43.34988 1.000 31.27318  ?  439 ASP B CB  1 
ATOM   7333 C  CG  . ASP B 1 439 ? 56.45590  5.33149   -44.49962 1.000 28.73710  ?  439 ASP B CG  1 
ATOM   7334 O  OD1 . ASP B 1 439 ? 56.07146  5.03589   -45.65063 1.000 27.22196  ?  439 ASP B OD1 1 
ATOM   7335 O  OD2 . ASP B 1 439 ? 57.60945  5.74120   -44.25171 1.000 33.96140  -1 439 ASP B OD2 1 
ATOM   7336 N  N   . TYR B 1 440 ? 53.57977  2.17750   -44.49139 1.000 29.55450  ?  440 TYR B N   1 
ATOM   7337 C  CA  . TYR B 1 440 ? 53.89447  0.84640   -44.98434 1.000 29.09686  ?  440 TYR B CA  1 
ATOM   7338 C  C   . TYR B 1 440 ? 54.02605  0.87394   -46.50216 1.000 28.12754  ?  440 TYR B C   1 
ATOM   7339 O  O   . TYR B 1 440 ? 53.28980  1.60605   -47.17341 1.000 29.04562  ?  440 TYR B O   1 
ATOM   7340 C  CB  . TYR B 1 440 ? 52.80890  -0.15352  -44.58011 1.000 30.74830  ?  440 TYR B CB  1 
ATOM   7341 C  CG  . TYR B 1 440 ? 53.08539  -1.56985  -45.02337 1.000 36.14289  ?  440 TYR B CG  1 
ATOM   7342 C  CD1 . TYR B 1 440 ? 53.83939  -2.43120  -44.23626 1.000 35.66616  ?  440 TYR B CD1 1 
ATOM   7343 C  CD2 . TYR B 1 440 ? 52.59866  -2.04433  -46.23322 1.000 37.59749  ?  440 TYR B CD2 1 
ATOM   7344 C  CE1 . TYR B 1 440 ? 54.09815  -3.72551  -44.64399 1.000 34.69100  ?  440 TYR B CE1 1 
ATOM   7345 C  CE2 . TYR B 1 440 ? 52.85328  -3.33153  -46.64810 1.000 33.05352  ?  440 TYR B CE2 1 
ATOM   7346 C  CZ  . TYR B 1 440 ? 53.60074  -4.16813  -45.85230 1.000 33.08004  ?  440 TYR B CZ  1 
ATOM   7347 O  OH  . TYR B 1 440 ? 53.84659  -5.45151  -46.27405 1.000 33.98976  ?  440 TYR B OH  1 
ATOM   7348 N  N   . PRO B 1 441 ? 54.95352  0.10536   -47.08272 1.000 29.23944  ?  441 PRO B N   1 
ATOM   7349 C  CA  . PRO B 1 441 ? 55.10761  0.12323   -48.54452 1.000 26.07704  ?  441 PRO B CA  1 
ATOM   7350 C  C   . PRO B 1 441 ? 53.87209  -0.38224  -49.27131 1.000 24.14611  ?  441 PRO B C   1 
ATOM   7351 O  O   . PRO B 1 441 ? 53.54955  -1.57248  -49.21184 1.000 28.00841  ?  441 PRO B O   1 
ATOM   7352 C  CB  . PRO B 1 441 ? 56.31241  -0.79820  -48.78187 1.000 29.90615  ?  441 PRO B CB  1 
ATOM   7353 C  CG  . PRO B 1 441 ? 56.42594  -1.62368  -47.53679 1.000 36.48192  ?  441 PRO B CG  1 
ATOM   7354 C  CD  . PRO B 1 441 ? 55.98142  -0.72309  -46.43108 1.000 35.36649  ?  441 PRO B CD  1 
ATOM   7355 N  N   . ILE B 1 442 ? 53.17397  0.51981   -49.96525 1.000 24.06042  ?  442 ILE B N   1 
ATOM   7356 C  CA  . ILE B 1 442 ? 51.96673  0.18165   -50.70704 1.000 23.93212  ?  442 ILE B CA  1 
ATOM   7357 C  C   . ILE B 1 442 ? 52.01344  0.86278   -52.06711 1.000 19.07409  ?  442 ILE B C   1 
ATOM   7358 O  O   . ILE B 1 442 ? 52.69963  1.86761   -52.26560 1.000 18.32829  ?  442 ILE B O   1 
ATOM   7359 C  CB  . ILE B 1 442 ? 50.67333  0.59354   -49.96697 1.000 19.03598  ?  442 ILE B CB  1 
ATOM   7360 C  CG1 . ILE B 1 442 ? 50.61060  2.11387   -49.81925 1.000 17.36165  ?  442 ILE B CG1 1 
ATOM   7361 C  CG2 . ILE B 1 442 ? 50.58096  -0.08873  -48.60895 1.000 15.30446  ?  442 ILE B CG2 1 
ATOM   7362 C  CD1 . ILE B 1 442 ? 49.22830  2.68359   -50.02110 1.000 15.41312  ?  442 ILE B CD1 1 
ATOM   7363 N  N   . VAL B 1 443 ? 51.26673  0.29467   -53.00968 1.000 20.34848  ?  443 VAL B N   1 
ATOM   7364 C  CA  . VAL B 1 443 ? 51.08428  0.87826   -54.33387 1.000 18.92498  ?  443 VAL B CA  1 
ATOM   7365 C  C   . VAL B 1 443 ? 49.61353  0.75617   -54.70765 1.000 20.23606  ?  443 VAL B C   1 
ATOM   7366 O  O   . VAL B 1 443 ? 49.00941  -0.30670  -54.53485 1.000 25.75915  ?  443 VAL B O   1 
ATOM   7367 C  CB  . VAL B 1 443 ? 51.97996  0.20667   -55.39555 1.000 16.07565  ?  443 VAL B CB  1 
ATOM   7368 C  CG1 . VAL B 1 443 ? 53.42929  0.61995   -55.20376 1.000 14.67467  ?  443 VAL B CG1 1 
ATOM   7369 C  CG2 . VAL B 1 443 ? 51.85066  -1.30812  -55.33160 1.000 17.79361  ?  443 VAL B CG2 1 
ATOM   7370 N  N   . ILE B 1 444 ? 49.03864  1.83640   -55.22079 1.000 12.70770  ?  444 ILE B N   1 
ATOM   7371 C  CA  . ILE B 1 444 ? 47.62825  1.86118   -55.59169 1.000 15.88480  ?  444 ILE B CA  1 
ATOM   7372 C  C   . ILE B 1 444 ? 47.48547  1.39712   -57.03561 1.000 14.57096  ?  444 ILE B C   1 
ATOM   7373 O  O   . ILE B 1 444 ? 48.23839  1.83034   -57.91618 1.000 19.34803  ?  444 ILE B O   1 
ATOM   7374 C  CB  . ILE B 1 444 ? 47.03113  3.26555   -55.39951 1.000 16.49362  ?  444 ILE B CB  1 
ATOM   7375 C  CG1 . ILE B 1 444 ? 46.97040  3.61968   -53.91161 1.000 16.53186  ?  444 ILE B CG1 1 
ATOM   7376 C  CG2 . ILE B 1 444 ? 45.64316  3.35032   -56.02112 1.000 14.96666  ?  444 ILE B CG2 1 
ATOM   7377 C  CD1 . ILE B 1 444 ? 46.04111  2.73898   -53.11084 1.000 14.95077  ?  444 ILE B CD1 1 
ATOM   7378 N  N   . SER B 1 445 ? 46.52370  0.51178   -57.27793 1.000 14.37190  ?  445 SER B N   1 
ATOM   7379 C  CA  . SER B 1 445 ? 46.25749  0.01205   -58.61822 1.000 15.34569  ?  445 SER B CA  1 
ATOM   7380 C  C   . SER B 1 445 ? 44.74788  -0.13363  -58.78404 1.000 15.77948  ?  445 SER B C   1 
ATOM   7381 O  O   . SER B 1 445 ? 43.96301  0.29409   -57.93020 1.000 16.71085  ?  445 SER B O   1 
ATOM   7382 C  CB  . SER B 1 445 ? 47.00638  -1.30337  -58.86557 1.000 19.82393  ?  445 SER B CB  1 
ATOM   7383 O  OG  . SER B 1 445 ? 47.05230  -1.61697  -60.24686 1.000 20.42865  ?  445 SER B OG  1 
ATOM   7384 N  N   . SER B 1 446 ? 44.33911  -0.75625  -59.89062 1.000 16.97866  ?  446 SER B N   1 
ATOM   7385 C  CA  . SER B 1 446 ? 42.93351  -0.84356  -60.24484 1.000 20.03350  ?  446 SER B CA  1 
ATOM   7386 C  C   . SER B 1 446 ? 42.39580  -2.26310  -60.37695 1.000 25.53227  ?  446 SER B C   1 
ATOM   7387 O  O   . SER B 1 446 ? 41.18294  -2.42452  -60.56468 1.000 27.20991  ?  446 SER B O   1 
ATOM   7388 C  CB  . SER B 1 446 ? 42.67329  -0.09942  -61.56315 1.000 20.49120  ?  446 SER B CB  1 
ATOM   7389 O  OG  . SER B 1 446 ? 43.63835  -0.42586  -62.54920 1.000 21.71835  ?  446 SER B OG  1 
ATOM   7390 N  N   . ASP B 1 447 ? 43.24409  -3.29066  -60.27805 1.000 27.12522  ?  447 ASP B N   1 
ATOM   7391 C  CA  . ASP B 1 447 ? 42.81703  -4.67112  -60.48811 1.000 24.30280  ?  447 ASP B CA  1 
ATOM   7392 C  C   . ASP B 1 447 ? 42.23222  -4.81330  -61.88494 1.000 27.73350  ?  447 ASP B C   1 
ATOM   7393 O  O   . ASP B 1 447 ? 42.96544  -4.79132  -62.87800 1.000 30.93721  ?  447 ASP B O   1 
ATOM   7394 C  CB  . ASP B 1 447 ? 41.79091  -5.12415  -59.44191 1.000 24.37360  ?  447 ASP B CB  1 
ATOM   7395 C  CG  . ASP B 1 447 ? 42.04081  -6.55118  -58.94639 1.000 26.11005  ?  447 ASP B CG  1 
ATOM   7396 O  OD1 . ASP B 1 447 ? 43.02179  -7.21495  -59.38294 1.000 33.96195  ?  447 ASP B OD1 1 
ATOM   7397 O  OD2 . ASP B 1 447 ? 41.24795  -6.99592  -58.08706 1.000 23.24703  -1 447 ASP B OD2 1 
ATOM   7398 N  N   . ASP B 1 448 ? 40.91316  -4.99167  -61.97738 1.000 24.72720  ?  448 ASP B N   1 
ATOM   7399 C  CA  . ASP B 1 448 ? 40.22274  -5.05912  -63.26328 1.000 20.24407  ?  448 ASP B CA  1 
ATOM   7400 C  C   . ASP B 1 448 ? 39.35275  -3.82175  -63.43393 1.000 20.54399  ?  448 ASP B C   1 
ATOM   7401 O  O   . ASP B 1 448 ? 38.14379  -3.87022  -63.17123 1.000 23.46296  ?  448 ASP B O   1 
ATOM   7402 C  CB  . ASP B 1 448 ? 39.37111  -6.32650  -63.34668 1.000 16.99701  ?  448 ASP B CB  1 
ATOM   7403 C  CG  . ASP B 1 448 ? 40.11039  -7.55978  -62.88488 1.000 20.68075  ?  448 ASP B CG  1 
ATOM   7404 O  OD1 . ASP B 1 448 ? 40.04897  -7.84828  -61.67398 1.000 19.93317  ?  448 ASP B OD1 1 
ATOM   7405 O  OD2 . ASP B 1 448 ? 40.74512  -8.23694  -63.72361 1.000 44.53476  -1 448 ASP B OD2 1 
ATOM   7406 N  N   . PRO B 1 449 ? 39.89531  -2.70159  -63.92456 1.000 21.87004  ?  449 PRO B N   1 
ATOM   7407 C  CA  . PRO B 1 449 ? 39.07545  -1.48672  -64.05807 1.000 23.28208  ?  449 PRO B CA  1 
ATOM   7408 C  C   . PRO B 1 449 ? 37.96495  -1.62011  -65.09186 1.000 22.57068  ?  449 PRO B C   1 
ATOM   7409 O  O   . PRO B 1 449 ? 36.79829  -1.33132  -64.79690 1.000 22.73156  ?  449 PRO B O   1 
ATOM   7410 C  CB  . PRO B 1 449 ? 40.10066  -0.41812  -64.46104 1.000 19.57144  ?  449 PRO B CB  1 
ATOM   7411 C  CG  . PRO B 1 449 ? 41.19871  -1.18504  -65.10705 1.000 20.19027  ?  449 PRO B CG  1 
ATOM   7412 C  CD  . PRO B 1 449 ? 41.28130  -2.48462  -64.37106 1.000 21.92058  ?  449 PRO B CD  1 
ATOM   7413 N  N   . GLY B 1 450 ? 38.30871  -2.09077  -66.29408 1.000 19.66278  ?  450 GLY B N   1 
ATOM   7414 C  CA  . GLY B 1 450 ? 37.33739  -2.16738  -67.37135 1.000 17.92110  ?  450 GLY B CA  1 
ATOM   7415 C  C   . GLY B 1 450 ? 36.13229  -3.02206  -67.04974 1.000 20.35913  ?  450 GLY B C   1 
ATOM   7416 O  O   . GLY B 1 450 ? 35.07568  -2.84311  -67.66455 1.000 19.90615  ?  450 GLY B O   1 
ATOM   7417 N  N   . ALA B 1 451 ? 36.26427  -3.94467  -66.09327 1.000 20.28600  ?  451 ALA B N   1 
ATOM   7418 C  CA  . ALA B 1 451 ? 35.12962  -4.77036  -65.69676 1.000 19.00382  ?  451 ALA B CA  1 
ATOM   7419 C  C   . ALA B 1 451 ? 34.00570  -3.92683  -65.10704 1.000 18.89423  ?  451 ALA B C   1 
ATOM   7420 O  O   . ALA B 1 451 ? 32.82463  -4.20788  -65.34192 1.000 13.91032  ?  451 ALA B O   1 
ATOM   7421 C  CB  . ALA B 1 451 ? 35.57790  -5.83909  -64.70043 1.000 13.80698  ?  451 ALA B CB  1 
ATOM   7422 N  N   . TRP B 1 452 ? 34.34587  -2.89101  -64.33473 1.000 21.90381  ?  452 TRP B N   1 
ATOM   7423 C  CA  . TRP B 1 452 ? 33.33724  -2.08958  -63.64878 1.000 21.51437  ?  452 TRP B CA  1 
ATOM   7424 C  C   . TRP B 1 452 ? 33.36601  -0.62418  -64.07693 1.000 24.71055  ?  452 TRP B C   1 
ATOM   7425 O  O   . TRP B 1 452 ? 33.04283  0.26354   -63.28433 1.000 25.68185  ?  452 TRP B O   1 
ATOM   7426 C  CB  . TRP B 1 452 ? 33.48794  -2.20822  -62.13231 1.000 20.72849  ?  452 TRP B CB  1 
ATOM   7427 C  CG  . TRP B 1 452 ? 34.90046  -2.13175  -61.63628 1.000 17.36043  ?  452 TRP B CG  1 
ATOM   7428 C  CD1 . TRP B 1 452 ? 35.69126  -1.02173  -61.57507 1.000 17.74047  ?  452 TRP B CD1 1 
ATOM   7429 C  CD2 . TRP B 1 452 ? 35.68091  -3.20959  -61.10742 1.000 16.79942  ?  452 TRP B CD2 1 
ATOM   7430 N  NE1 . TRP B 1 452 ? 36.91986  -1.34367  -61.05144 1.000 15.90094  ?  452 TRP B NE1 1 
ATOM   7431 C  CE2 . TRP B 1 452 ? 36.93798  -2.68091  -60.75379 1.000 19.26532  ?  452 TRP B CE2 1 
ATOM   7432 C  CE3 . TRP B 1 452 ? 35.43978  -4.57142  -60.90216 1.000 16.26564  ?  452 TRP B CE3 1 
ATOM   7433 C  CZ2 . TRP B 1 452 ? 37.95123  -3.46696  -60.20793 1.000 20.30306  ?  452 TRP B CZ2 1 
ATOM   7434 C  CZ3 . TRP B 1 452 ? 36.44595  -5.34876  -60.36045 1.000 18.28815  ?  452 TRP B CZ3 1 
ATOM   7435 C  CH2 . TRP B 1 452 ? 37.68633  -4.79570  -60.02303 1.000 16.42535  ?  452 TRP B CH2 1 
ATOM   7436 N  N   . GLU B 1 453 ? 33.73935  -0.36353  -65.32911 1.000 21.96108  ?  453 GLU B N   1 
ATOM   7437 C  CA  . GLU B 1 453 ? 33.69289  0.97260   -65.92614 1.000 22.69894  ?  453 GLU B CA  1 
ATOM   7438 C  C   . GLU B 1 453 ? 34.44805  1.99631   -65.07647 1.000 23.71109  ?  453 GLU B C   1 
ATOM   7439 O  O   . GLU B 1 453 ? 33.91429  3.02983   -64.66885 1.000 24.01897  ?  453 GLU B O   1 
ATOM   7440 C  CB  . GLU B 1 453 ? 32.24602  1.41905   -66.15419 1.000 22.08144  ?  453 GLU B CB  1 
ATOM   7441 C  CG  . GLU B 1 453 ? 31.43665  0.50346   -67.05422 1.000 25.94421  ?  453 GLU B CG  1 
ATOM   7442 C  CD  . GLU B 1 453 ? 30.05182  1.05244   -67.34407 1.000 33.80143  ?  453 GLU B CD  1 
ATOM   7443 O  OE1 . GLU B 1 453 ? 29.91172  2.28932   -67.44998 1.000 40.58204  ?  453 GLU B OE1 1 
ATOM   7444 O  OE2 . GLU B 1 453 ? 29.10223  0.24910   -67.46008 1.000 30.59986  -1 453 GLU B OE2 1 
ATOM   7445 N  N   . ALA B 1 454 ? 35.71248  1.69021   -64.81379 1.000 18.56314  ?  454 ALA B N   1 
ATOM   7446 C  CA  . ALA B 1 454 ? 36.59318  2.58592   -64.08372 1.000 19.16999  ?  454 ALA B CA  1 
ATOM   7447 C  C   . ALA B 1 454 ? 37.71209  3.06563   -64.99736 1.000 29.07442  ?  454 ALA B C   1 
ATOM   7448 O  O   . ALA B 1 454 ? 38.16634  2.33763   -65.88507 1.000 37.16485  ?  454 ALA B O   1 
ATOM   7449 C  CB  . ALA B 1 454 ? 37.18516  1.90029   -62.84887 1.000 21.66400  ?  454 ALA B CB  1 
ATOM   7450 N  N   . SER B 1 455 ? 38.14701  4.30349   -64.77589 1.000 21.21389  ?  455 SER B N   1 
ATOM   7451 C  CA  . SER B 1 455 ? 39.27278  4.83381   -65.52425 1.000 17.91154  ?  455 SER B CA  1 
ATOM   7452 C  C   . SER B 1 455 ? 40.52997  4.03345   -65.18205 1.000 21.07176  ?  455 SER B C   1 
ATOM   7453 O  O   . SER B 1 455 ? 40.60536  3.42106   -64.11193 1.000 22.68531  ?  455 SER B O   1 
ATOM   7454 C  CB  . SER B 1 455 ? 39.47218  6.31587   -65.20934 1.000 20.97103  ?  455 SER B CB  1 
ATOM   7455 O  OG  . SER B 1 455 ? 39.65897  6.52551   -63.82317 1.000 22.17146  ?  455 SER B OG  1 
ATOM   7456 N  N   . PRO B 1 456 ? 41.52664  3.99777   -66.09330 1.000 19.05345  ?  456 PRO B N   1 
ATOM   7457 C  CA  . PRO B 1 456 ? 42.69573  3.12419   -65.89605 1.000 20.36108  ?  456 PRO B CA  1 
ATOM   7458 C  C   . PRO B 1 456 ? 43.29067  3.16634   -64.49593 1.000 22.04102  ?  456 PRO B C   1 
ATOM   7459 O  O   . PRO B 1 456 ? 43.41045  2.12595   -63.84186 1.000 21.24064  ?  456 PRO B O   1 
ATOM   7460 C  CB  . PRO B 1 456 ? 43.68968  3.64932   -66.93805 1.000 19.76325  ?  456 PRO B CB  1 
ATOM   7461 C  CG  . PRO B 1 456 ? 42.81890  4.13387   -68.04283 1.000 21.29143  ?  456 PRO B CG  1 
ATOM   7462 C  CD  . PRO B 1 456 ? 41.58932  4.70991   -67.38358 1.000 19.85740  ?  456 PRO B CD  1 
ATOM   7463 N  N   . LEU B 1 457 ? 43.67035  4.35319   -64.02508 1.000 25.07027  ?  457 LEU B N   1 
ATOM   7464 C  CA  . LEU B 1 457 ? 44.17003  4.48863   -62.66240 1.000 19.52441  ?  457 LEU B CA  1 
ATOM   7465 C  C   . LEU B 1 457 ? 43.64218  5.71221   -61.92702 1.000 21.51709  ?  457 LEU B C   1 
ATOM   7466 O  O   . LEU B 1 457 ? 43.77888  5.76863   -60.70095 1.000 18.18509  ?  457 LEU B O   1 
ATOM   7467 C  CB  . LEU B 1 457 ? 45.70657  4.52187   -62.66574 1.000 19.13718  ?  457 LEU B CB  1 
ATOM   7468 C  CG  . LEU B 1 457 ? 46.42884  4.24592   -61.34616 1.000 17.26468  ?  457 LEU B CG  1 
ATOM   7469 C  CD1 . LEU B 1 457 ? 45.80670  3.05445   -60.64039 1.000 22.23476  ?  457 LEU B CD1 1 
ATOM   7470 C  CD2 . LEU B 1 457 ? 47.91220  4.01271   -61.58592 1.000 20.04675  ?  457 LEU B CD2 1 
ATOM   7471 N  N   . SER B 1 458 ? 43.03073  6.67893   -62.61791 1.000 23.07835  ?  458 SER B N   1 
ATOM   7472 C  CA  . SER B 1 458 ? 42.63444  7.92857   -61.97371 1.000 23.58090  ?  458 SER B CA  1 
ATOM   7473 C  C   . SER B 1 458 ? 41.55506  7.71079   -60.92021 1.000 24.96732  ?  458 SER B C   1 
ATOM   7474 O  O   . SER B 1 458 ? 41.57739  8.35321   -59.86506 1.000 26.61842  ?  458 SER B O   1 
ATOM   7475 C  CB  . SER B 1 458 ? 42.15691  8.93083   -63.02356 1.000 23.16011  ?  458 SER B CB  1 
ATOM   7476 O  OG  . SER B 1 458 ? 43.22621  9.36051   -63.84431 1.000 28.05785  ?  458 SER B OG  1 
ATOM   7477 N  N   . HIS B 1 459 ? 40.59055  6.82970   -61.19310 1.000 21.26416  ?  459 HIS B N   1 
ATOM   7478 C  CA  . HIS B 1 459 ? 39.48245  6.64206   -60.26106 1.000 19.99247  ?  459 HIS B CA  1 
ATOM   7479 C  C   . HIS B 1 459 ? 39.94863  6.01127   -58.95446 1.000 18.81517  ?  459 HIS B C   1 
ATOM   7480 O  O   . HIS B 1 459 ? 39.54875  6.45201   -57.86955 1.000 20.95414  ?  459 HIS B O   1 
ATOM   7481 C  CB  . HIS B 1 459 ? 38.38638  5.80011   -60.91193 1.000 25.55767  ?  459 HIS B CB  1 
ATOM   7482 C  CG  . HIS B 1 459 ? 37.36054  6.61060   -61.64182 1.000 19.73139  ?  459 HIS B CG  1 
ATOM   7483 N  ND1 . HIS B 1 459 ? 36.79590  6.20364   -62.83131 1.000 19.84932  ?  459 HIS B ND1 1 
ATOM   7484 C  CD2 . HIS B 1 459 ? 36.79214  7.80318   -61.34470 1.000 16.58217  ?  459 HIS B CD2 1 
ATOM   7485 C  CE1 . HIS B 1 459 ? 35.92686  7.11204   -63.23750 1.000 19.51984  ?  459 HIS B CE1 1 
ATOM   7486 N  NE2 . HIS B 1 459 ? 35.90508  8.09245   -62.35283 1.000 18.67294  ?  459 HIS B NE2 1 
ATOM   7487 N  N   . ASP B 1 460 ? 40.79261  4.98083   -59.03312 1.000 21.23624  ?  460 ASP B N   1 
ATOM   7488 C  CA  . ASP B 1 460 ? 41.32237  4.38222   -57.81271 1.000 22.20838  ?  460 ASP B CA  1 
ATOM   7489 C  C   . ASP B 1 460 ? 42.19686  5.37136   -57.05177 1.000 24.26600  ?  460 ASP B C   1 
ATOM   7490 O  O   . ASP B 1 460 ? 42.19053  5.38936   -55.81562 1.000 22.16159  ?  460 ASP B O   1 
ATOM   7491 C  CB  . ASP B 1 460 ? 42.09753  3.10707   -58.14299 1.000 21.81780  ?  460 ASP B CB  1 
ATOM   7492 C  CG  . ASP B 1 460 ? 41.19256  1.98047   -58.60593 1.000 29.82461  ?  460 ASP B CG  1 
ATOM   7493 O  OD1 . ASP B 1 460 ? 40.77143  1.99730   -59.78243 1.000 35.29347  ?  460 ASP B OD1 1 
ATOM   7494 O  OD2 . ASP B 1 460 ? 40.89579  1.08171   -57.79004 1.000 29.02917  -1 460 ASP B OD2 1 
ATOM   7495 N  N   . PHE B 1 461 ? 42.94532  6.21070   -57.77187 1.000 25.86745  ?  461 PHE B N   1 
ATOM   7496 C  CA  . PHE B 1 461 ? 43.74807  7.23580   -57.11181 1.000 22.33354  ?  461 PHE B CA  1 
ATOM   7497 C  C   . PHE B 1 461 ? 42.87011  8.25375   -56.39199 1.000 20.67261  ?  461 PHE B C   1 
ATOM   7498 O  O   . PHE B 1 461 ? 43.19484  8.68386   -55.28037 1.000 19.56573  ?  461 PHE B O   1 
ATOM   7499 C  CB  . PHE B 1 461 ? 44.65928  7.92502   -58.12705 1.000 22.09507  ?  461 PHE B CB  1 
ATOM   7500 C  CG  . PHE B 1 461 ? 46.09728  7.49742   -58.03556 1.000 25.10266  ?  461 PHE B CG  1 
ATOM   7501 C  CD1 . PHE B 1 461 ? 46.48421  6.23006   -58.43744 1.000 28.84142  ?  461 PHE B CD1 1 
ATOM   7502 C  CD2 . PHE B 1 461 ? 47.06222  8.36271   -57.54740 1.000 23.62737  ?  461 PHE B CD2 1 
ATOM   7503 C  CE1 . PHE B 1 461 ? 47.80691  5.83214   -58.35384 1.000 23.28904  ?  461 PHE B CE1 1 
ATOM   7504 C  CE2 . PHE B 1 461 ? 48.38599  7.97107   -57.46137 1.000 24.15311  ?  461 PHE B CE2 1 
ATOM   7505 C  CZ  . PHE B 1 461 ? 48.75828  6.70389   -57.86509 1.000 20.73397  ?  461 PHE B CZ  1 
ATOM   7506 N  N   . TYR B 1 462 ? 41.75565  8.65592   -57.00938 1.000 20.53391  ?  462 TYR B N   1 
ATOM   7507 C  CA  . TYR B 1 462 ? 40.83518  9.57517   -56.34435 1.000 20.84133  ?  462 TYR B CA  1 
ATOM   7508 C  C   . TYR B 1 462 ? 40.20340  8.93311   -55.11582 1.000 21.73042  ?  462 TYR B C   1 
ATOM   7509 O  O   . TYR B 1 462 ? 40.03008  9.59193   -54.08170 1.000 28.45548  ?  462 TYR B O   1 
ATOM   7510 C  CB  . TYR B 1 462 ? 39.75146  10.04270  -57.31615 1.000 17.38588  ?  462 TYR B CB  1 
ATOM   7511 C  CG  . TYR B 1 462 ? 38.77405  11.02125  -56.70028 1.000 19.67721  ?  462 TYR B CG  1 
ATOM   7512 C  CD1 . TYR B 1 462 ? 39.02795  12.38628  -56.71354 1.000 25.67014  ?  462 TYR B CD1 1 
ATOM   7513 C  CD2 . TYR B 1 462 ? 37.60131  10.58056  -56.09973 1.000 19.64998  ?  462 TYR B CD2 1 
ATOM   7514 C  CE1 . TYR B 1 462 ? 38.14079  13.28506  -56.14852 1.000 26.63622  ?  462 TYR B CE1 1 
ATOM   7515 C  CE2 . TYR B 1 462 ? 36.71138  11.47169  -55.52998 1.000 23.13387  ?  462 TYR B CE2 1 
ATOM   7516 C  CZ  . TYR B 1 462 ? 36.98342  12.82185  -55.56026 1.000 25.67599  ?  462 TYR B CZ  1 
ATOM   7517 O  OH  . TYR B 1 462 ? 36.09623  13.71070  -54.99627 1.000 31.69526  ?  462 TYR B OH  1 
ATOM   7518 N  N   . VAL B 1 463 ? 39.83318  7.65493   -55.21845 1.000 19.81116  ?  463 VAL B N   1 
ATOM   7519 C  CA  . VAL B 1 463 ? 39.28381  6.94789   -54.06515 1.000 14.04345  ?  463 VAL B CA  1 
ATOM   7520 C  C   . VAL B 1 463 ? 40.30731  6.90468   -52.93805 1.000 17.01378  ?  463 VAL B C   1 
ATOM   7521 O  O   . VAL B 1 463 ? 39.97620  7.12759   -51.76655 1.000 17.18978  ?  463 VAL B O   1 
ATOM   7522 C  CB  . VAL B 1 463 ? 38.82227  5.53600   -54.47241 1.000 12.43167  ?  463 VAL B CB  1 
ATOM   7523 C  CG1 . VAL B 1 463 ? 38.44266  4.73072   -53.24941 1.000 10.27015  ?  463 VAL B CG1 1 
ATOM   7524 C  CG2 . VAL B 1 463 ? 37.64632  5.61803   -55.43199 1.000 13.63967  ?  463 VAL B CG2 1 
ATOM   7525 N  N   . ALA B 1 464 ? 41.56923  6.63017   -53.27579 1.000 18.79883  ?  464 ALA B N   1 
ATOM   7526 C  CA  . ALA B 1 464 ? 42.62380  6.62687   -52.26791 1.000 22.78069  ?  464 ALA B CA  1 
ATOM   7527 C  C   . ALA B 1 464 ? 42.79725  8.00531   -51.64409 1.000 21.35452  ?  464 ALA B C   1 
ATOM   7528 O  O   . ALA B 1 464 ? 42.97850  8.12674   -50.42681 1.000 26.12413  ?  464 ALA B O   1 
ATOM   7529 C  CB  . ALA B 1 464 ? 43.93744  6.14858   -52.88584 1.000 22.75043  ?  464 ALA B CB  1 
ATOM   7530 N  N   . LEU B 1 465 ? 42.74692  9.05542   -52.46490 1.000 19.52968  ?  465 LEU B N   1 
ATOM   7531 C  CA  . LEU B 1 465 ? 42.90806  10.41263  -51.95432 1.000 21.65267  ?  465 LEU B CA  1 
ATOM   7532 C  C   . LEU B 1 465 ? 41.79632  10.77096  -50.97830 1.000 18.08938  ?  465 LEU B C   1 
ATOM   7533 O  O   . LEU B 1 465 ? 42.04975  11.33290  -49.90775 1.000 18.62973  ?  465 LEU B O   1 
ATOM   7534 C  CB  . LEU B 1 465 ? 42.93489  11.40756  -53.11487 1.000 21.07413  ?  465 LEU B CB  1 
ATOM   7535 C  CG  . LEU B 1 465 ? 42.62899  12.86181  -52.74662 1.000 20.42985  ?  465 LEU B CG  1 
ATOM   7536 C  CD1 . LEU B 1 465 ? 43.78742  13.48028  -51.97944 1.000 23.89626  ?  465 LEU B CD1 1 
ATOM   7537 C  CD2 . LEU B 1 465 ? 42.28803  13.68354  -53.98305 1.000 18.97033  ?  465 LEU B CD2 1 
ATOM   7538 N  N   . MET B 1 466 ? 40.55595  10.44953  -51.32849 1.000 19.93871  ?  466 MET B N   1 
ATOM   7539 C  CA  . MET B 1 466 ? 39.41819  10.90561  -50.54381 1.000 21.35536  ?  466 MET B CA  1 
ATOM   7540 C  C   . MET B 1 466 ? 38.99911  9.93452   -49.44684 1.000 18.25725  ?  466 MET B C   1 
ATOM   7541 O  O   . MET B 1 466 ? 38.13376  10.28356  -48.63672 1.000 14.60594  ?  466 MET B O   1 
ATOM   7542 C  CB  . MET B 1 466 ? 38.22586  11.17773  -51.46520 1.000 19.20977  ?  466 MET B CB  1 
ATOM   7543 C  CG  . MET B 1 466 ? 38.50000  12.21358  -52.54198 1.000 16.79591  ?  466 MET B CG  1 
ATOM   7544 S  SD  . MET B 1 466 ? 38.78274  13.86394  -51.87526 1.000 24.58171  ?  466 MET B SD  1 
ATOM   7545 C  CE  . MET B 1 466 ? 37.15477  14.26143  -51.24746 1.000 17.87019  ?  466 MET B CE  1 
ATOM   7546 N  N   . ASP B 1 467 ? 39.58199  8.73762   -49.38524 1.000 15.60783  ?  467 ASP B N   1 
ATOM   7547 C  CA  . ASP B 1 467 ? 39.14142  7.74418   -48.41382 1.000 18.15253  ?  467 ASP B CA  1 
ATOM   7548 C  C   . ASP B 1 467 ? 40.25598  7.08099   -47.61804 1.000 15.61775  ?  467 ASP B C   1 
ATOM   7549 O  O   . ASP B 1 467 ? 39.97418  6.56673   -46.52891 1.000 15.80634  ?  467 ASP B O   1 
ATOM   7550 C  CB  . ASP B 1 467 ? 38.31903  6.64658   -49.10792 1.000 17.62691  ?  467 ASP B CB  1 
ATOM   7551 C  CG  . ASP B 1 467 ? 36.97610  7.14990   -49.60612 1.000 13.25495  ?  467 ASP B CG  1 
ATOM   7552 O  OD1 . ASP B 1 467 ? 36.39274  8.03661   -48.94873 1.000 16.96135  ?  467 ASP B OD1 1 
ATOM   7553 O  OD2 . ASP B 1 467 ? 36.50278  6.65955   -50.65313 1.000 10.92639  -1 467 ASP B OD2 1 
ATOM   7554 N  N   . LEU B 1 468 ? 41.49661  7.07128   -48.10154 1.000 14.83342  ?  468 LEU B N   1 
ATOM   7555 C  CA  . LEU B 1 468 ? 42.55905  6.31065   -47.45728 1.000 19.47871  ?  468 LEU B CA  1 
ATOM   7556 C  C   . LEU B 1 468 ? 43.56787  7.17401   -46.71031 1.000 20.07827  ?  468 LEU B C   1 
ATOM   7557 O  O   . LEU B 1 468 ? 44.49888  6.62703   -46.10878 1.000 15.69967  ?  468 LEU B O   1 
ATOM   7558 C  CB  . LEU B 1 468 ? 43.29049  5.44534   -48.49117 1.000 22.02420  ?  468 LEU B CB  1 
ATOM   7559 C  CG  . LEU B 1 468 ? 42.42936  4.54641   -49.38451 1.000 17.14223  ?  468 LEU B CG  1 
ATOM   7560 C  CD1 . LEU B 1 468 ? 43.30389  3.59307   -50.18707 1.000 12.36544  ?  468 LEU B CD1 1 
ATOM   7561 C  CD2 . LEU B 1 468 ? 41.38631  3.78271   -48.58442 1.000 20.05990  ?  468 LEU B CD2 1 
ATOM   7562 N  N   . CYS B 1 469 ? 43.41621  8.49698   -46.72421 1.000 22.68033  ?  469 CYS B N   1 
ATOM   7563 C  CA  . CYS B 1 469 ? 44.32462  9.38063   -46.00653 1.000 22.07892  ?  469 CYS B CA  1 
ATOM   7564 C  C   . CYS B 1 469 ? 43.52312  10.48682  -45.33494 1.000 23.88186  ?  469 CYS B C   1 
ATOM   7565 O  O   . CYS B 1 469 ? 42.35051  10.71449  -45.64565 1.000 25.46876  ?  469 CYS B O   1 
ATOM   7566 C  CB  . CYS B 1 469 ? 45.40081  9.96449   -46.93221 1.000 17.33986  ?  469 CYS B CB  1 
ATOM   7567 S  SG  . CYS B 1 469 ? 44.76691  10.84308  -48.36931 1.000 25.71593  ?  469 CYS B SG  1 
ATOM   7568 N  N   . GLY B 1 470 ? 44.17420  11.17683  -44.40330 1.000 19.98443  ?  470 GLY B N   1 
ATOM   7569 C  CA  . GLY B 1 470 ? 43.48792  12.12721  -43.55478 1.000 22.52315  ?  470 GLY B CA  1 
ATOM   7570 C  C   . GLY B 1 470 ? 43.13220  13.42712  -44.25376 1.000 27.24714  ?  470 GLY B C   1 
ATOM   7571 O  O   . GLY B 1 470 ? 43.51985  13.70415  -45.38883 1.000 26.66225  ?  470 GLY B O   1 
ATOM   7572 N  N   . ARG B 1 471 ? 42.37682  14.24989  -43.52024 1.000 27.23977  ?  471 ARG B N   1 
ATOM   7573 C  CA  . ARG B 1 471 ? 41.86293  15.50803  -44.05464 1.000 28.98193  ?  471 ARG B CA  1 
ATOM   7574 C  C   . ARG B 1 471 ? 42.98254  16.45593  -44.47087 1.000 31.64933  ?  471 ARG B C   1 
ATOM   7575 O  O   . ARG B 1 471 ? 42.79258  17.28348  -45.37000 1.000 26.98022  ?  471 ARG B O   1 
ATOM   7576 C  CB  . ARG B 1 471 ? 40.95953  16.16413  -43.00763 1.000 22.65877  ?  471 ARG B CB  1 
ATOM   7577 C  CG  . ARG B 1 471 ? 40.41718  17.53518  -43.36347 1.000 21.49784  ?  471 ARG B CG  1 
ATOM   7578 C  CD  . ARG B 1 471 ? 39.63657  18.11021  -42.19132 1.000 24.75577  ?  471 ARG B CD  1 
ATOM   7579 N  NE  . ARG B 1 471 ? 39.03364  19.39927  -42.50468 1.000 25.11376  ?  471 ARG B NE  1 
ATOM   7580 C  CZ  . ARG B 1 471 ? 39.60636  20.57066  -42.26653 1.000 30.14634  ?  471 ARG B CZ  1 
ATOM   7581 N  NH1 . ARG B 1 471 ? 40.80489  20.65393  -41.71236 1.000 37.99493  ?  471 ARG B NH1 1 
ATOM   7582 N  NH2 . ARG B 1 471 ? 38.95981  21.68654  -42.59117 1.000 29.42778  ?  471 ARG B NH2 1 
ATOM   7583 N  N   . ASP B 1 472 ? 44.15403  16.34837  -43.84335 1.000 28.33118  ?  472 ASP B N   1 
ATOM   7584 C  CA  . ASP B 1 472 ? 45.27762  17.23543  -44.11770 1.000 26.14804  ?  472 ASP B CA  1 
ATOM   7585 C  C   . ASP B 1 472 ? 46.30579  16.60462  -45.05481 1.000 34.76760  ?  472 ASP B C   1 
ATOM   7586 O  O   . ASP B 1 472 ? 47.49105  16.95000  -44.99387 1.000 36.29996  ?  472 ASP B O   1 
ATOM   7587 C  CB  . ASP B 1 472 ? 45.94470  17.65768  -42.80776 1.000 30.79407  ?  472 ASP B CB  1 
ATOM   7588 C  CG  . ASP B 1 472 ? 44.96371  18.26115  -41.81746 1.000 23.91415  ?  472 ASP B CG  1 
ATOM   7589 O  OD1 . ASP B 1 472 ? 43.94695  18.83632  -42.25684 1.000 29.40962  ?  472 ASP B OD1 1 
ATOM   7590 O  OD2 . ASP B 1 472 ? 45.21110  18.16228  -40.59699 1.000 17.87794  -1 472 ASP B OD2 1 
ATOM   7591 N  N   . THR B 1 473 ? 45.87801  15.68936  -45.92592 1.000 34.81716  ?  473 THR B N   1 
ATOM   7592 C  CA  . THR B 1 473 ? 46.78390  14.94342  -46.79810 1.000 30.32529  ?  473 THR B CA  1 
ATOM   7593 C  C   . THR B 1 473 ? 46.21368  14.92530  -48.21070 1.000 21.64179  ?  473 THR B C   1 
ATOM   7594 O  O   . THR B 1 473 ? 45.20914  14.25285  -48.46391 1.000 21.15894  ?  473 THR B O   1 
ATOM   7595 C  CB  . THR B 1 473 ? 46.98069  13.51578  -46.28526 1.000 22.85570  ?  473 THR B CB  1 
ATOM   7596 O  OG1 . THR B 1 473 ? 47.18669  13.53656  -44.86724 1.000 20.34759  ?  473 THR B OG1 1 
ATOM   7597 C  CG2 . THR B 1 473 ? 48.17806  12.86657  -46.96038 1.000 23.71943  ?  473 THR B CG2 1 
ATOM   7598 N  N   . ALA B 1 474 ? 46.83416  15.67149  -49.12915 1.000 15.24459  ?  474 ALA B N   1 
ATOM   7599 C  CA  . ALA B 1 474 ? 46.39192  15.66966  -50.52104 1.000 17.87771  ?  474 ALA B CA  1 
ATOM   7600 C  C   . ALA B 1 474 ? 47.45573  15.18129  -51.49608 1.000 20.45221  ?  474 ALA B C   1 
ATOM   7601 O  O   . ALA B 1 474 ? 47.22260  14.19630  -52.20374 1.000 26.29640  ?  474 ALA B O   1 
ATOM   7602 C  CB  . ALA B 1 474 ? 45.91638  17.07072  -50.92193 1.000 24.53425  ?  474 ALA B CB  1 
ATOM   7603 N  N   . LEU B 1 475 ? 48.62384  15.82394  -51.55138 1.000 20.75463  ?  475 LEU B N   1 
ATOM   7604 C  CA  . LEU B 1 475 ? 49.53604  15.64447  -52.67667 1.000 21.58960  ?  475 LEU B CA  1 
ATOM   7605 C  C   . LEU B 1 475 ? 50.82387  14.91716  -52.33234 1.000 19.66122  ?  475 LEU B C   1 
ATOM   7606 O  O   . LEU B 1 475 ? 51.35621  14.20380  -53.18660 1.000 23.72922  ?  475 LEU B O   1 
ATOM   7607 C  CB  . LEU B 1 475 ? 49.89038  17.00096  -53.30039 1.000 20.63765  ?  475 LEU B CB  1 
ATOM   7608 C  CG  . LEU B 1 475 ? 50.74324  16.94977  -54.57095 1.000 14.31286  ?  475 LEU B CG  1 
ATOM   7609 C  CD1 . LEU B 1 475 ? 50.08446  16.06699  -55.61712 1.000 16.05200  ?  475 LEU B CD1 1 
ATOM   7610 C  CD2 . LEU B 1 475 ? 50.98326  18.34034  -55.12269 1.000 16.75240  ?  475 LEU B CD2 1 
ATOM   7611 N  N   . THR B 1 476 ? 51.35139  15.08918  -51.11921 1.000 18.17089  ?  476 THR B N   1 
ATOM   7612 C  CA  . THR B 1 476 ? 52.49283  14.27966  -50.70948 1.000 24.14006  ?  476 THR B CA  1 
ATOM   7613 C  C   . THR B 1 476 ? 52.15491  12.79826  -50.80406 1.000 26.66089  ?  476 THR B C   1 
ATOM   7614 O  O   . THR B 1 476 ? 52.98051  11.98880  -51.24235 1.000 24.75103  ?  476 THR B O   1 
ATOM   7615 C  CB  . THR B 1 476 ? 52.92195  14.64766  -49.28846 1.000 23.15382  ?  476 THR B CB  1 
ATOM   7616 O  OG1 . THR B 1 476 ? 51.87577  14.31637  -48.36687 1.000 22.11768  ?  476 THR B OG1 1 
ATOM   7617 C  CG2 . THR B 1 476 ? 53.22083  16.13632  -49.19207 1.000 26.71993  ?  476 THR B CG2 1 
ATOM   7618 N  N   . PHE B 1 477 ? 50.92302  12.43795  -50.43739 1.000 27.02249  ?  477 PHE B N   1 
ATOM   7619 C  CA  . PHE B 1 477 ? 50.47500  11.05245  -50.52697 1.000 23.23393  ?  477 PHE B CA  1 
ATOM   7620 C  C   . PHE B 1 477 ? 50.47632  10.55734  -51.97038 1.000 20.64467  ?  477 PHE B C   1 
ATOM   7621 O  O   . PHE B 1 477 ? 50.97712  9.46580   -52.26128 1.000 23.97769  ?  477 PHE B O   1 
ATOM   7622 C  CB  . PHE B 1 477 ? 49.08257  10.93419  -49.90377 1.000 28.84976  ?  477 PHE B CB  1 
ATOM   7623 C  CG  . PHE B 1 477 ? 48.44032  9.58814   -50.07827 1.000 31.82587  ?  477 PHE B CG  1 
ATOM   7624 C  CD1 . PHE B 1 477 ? 49.03212  8.44777   -49.56111 1.000 24.09218  ?  477 PHE B CD1 1 
ATOM   7625 C  CD2 . PHE B 1 477 ? 47.22450  9.46933   -50.73469 1.000 24.19701  ?  477 PHE B CD2 1 
ATOM   7626 C  CE1 . PHE B 1 477 ? 48.43393  7.21147   -49.71417 1.000 22.50705  ?  477 PHE B CE1 1 
ATOM   7627 C  CE2 . PHE B 1 477 ? 46.62006  8.23721   -50.88905 1.000 17.03710  ?  477 PHE B CE2 1 
ATOM   7628 C  CZ  . PHE B 1 477 ? 47.22503  7.10674   -50.37836 1.000 25.44183  ?  477 PHE B CZ  1 
ATOM   7629 N  N   . LEU B 1 478 ? 49.92589  11.35155  -52.89369 1.000 18.90030  ?  478 LEU B N   1 
ATOM   7630 C  CA  . LEU B 1 478 ? 49.85506  10.91981  -54.28875 1.000 23.39938  ?  478 LEU B CA  1 
ATOM   7631 C  C   . LEU B 1 478 ? 51.24220  10.82259  -54.91597 1.000 24.35985  ?  478 LEU B C   1 
ATOM   7632 O  O   . LEU B 1 478 ? 51.53228  9.87425   -55.66002 1.000 24.89934  ?  478 LEU B O   1 
ATOM   7633 C  CB  . LEU B 1 478 ? 48.96633  11.87202  -55.08997 1.000 28.98874  ?  478 LEU B CB  1 
ATOM   7634 C  CG  . LEU B 1 478 ? 47.50106  11.96863  -54.65407 1.000 25.62602  ?  478 LEU B CG  1 
ATOM   7635 C  CD1 . LEU B 1 478 ? 46.70324  12.83526  -55.61861 1.000 19.24024  ?  478 LEU B CD1 1 
ATOM   7636 C  CD2 . LEU B 1 478 ? 46.87969  10.58545  -54.53097 1.000 19.91630  ?  478 LEU B CD2 1 
ATOM   7637 N  N   . LYS B 1 479 ? 52.11321  11.79340  -54.63015 1.000 31.09408  ?  479 LYS B N   1 
ATOM   7638 C  CA  . LYS B 1 479 ? 53.47344  11.72991  -55.15273 1.000 29.52832  ?  479 LYS B CA  1 
ATOM   7639 C  C   . LYS B 1 479 ? 54.21853  10.52870  -54.58405 1.000 26.93996  ?  479 LYS B C   1 
ATOM   7640 O  O   . LYS B 1 479 ? 54.99011  9.87349   -55.29565 1.000 26.18771  ?  479 LYS B O   1 
ATOM   7641 C  CB  . LYS B 1 479 ? 54.22070  13.02982  -54.84952 1.000 24.43353  ?  479 LYS B CB  1 
ATOM   7642 C  CG  . LYS B 1 479 ? 55.50940  13.19548  -55.64386 1.000 25.00177  ?  479 LYS B CG  1 
ATOM   7643 C  CD  . LYS B 1 479 ? 56.12687  14.57066  -55.44179 1.000 24.06669  ?  479 LYS B CD  1 
ATOM   7644 C  CE  . LYS B 1 479 ? 57.33854  14.76592  -56.34227 1.000 23.04427  ?  479 LYS B CE  1 
ATOM   7645 N  NZ  . LYS B 1 479 ? 57.96308  16.10667  -56.16750 1.000 21.41018  ?  479 LYS B NZ  1 
ATOM   7646 N  N   . GLN B 1 480 ? 53.99276  10.21439  -53.30424 1.000 26.03559  ?  480 GLN B N   1 
ATOM   7647 C  CA  . GLN B 1 480 ? 54.61061  9.02916   -52.72293 1.000 23.83482  ?  480 GLN B CA  1 
ATOM   7648 C  C   . GLN B 1 480 ? 54.07868  7.75816   -53.36809 1.000 25.54967  ?  480 GLN B C   1 
ATOM   7649 O  O   . GLN B 1 480 ? 54.82680  6.79376   -53.55065 1.000 26.47541  ?  480 GLN B O   1 
ATOM   7650 C  CB  . GLN B 1 480 ? 54.38235  8.99389   -51.21441 1.000 20.30809  ?  480 GLN B CB  1 
ATOM   7651 C  CG  . GLN B 1 480 ? 55.26693  7.98738   -50.50073 1.000 20.49575  ?  480 GLN B CG  1 
ATOM   7652 C  CD  . GLN B 1 480 ? 56.73877  8.34161   -50.59975 1.000 19.26667  ?  480 GLN B CD  1 
ATOM   7653 O  OE1 . GLN B 1 480 ? 57.12065  9.50015   -50.44692 1.000 26.03092  ?  480 GLN B OE1 1 
ATOM   7654 N  NE2 . GLN B 1 480 ? 57.57196  7.34473   -50.86234 1.000 18.36100  ?  480 GLN B NE2 1 
ATOM   7655 N  N   . LEU B 1 481 ? 52.78562  7.72870   -53.69879 1.000 25.40607  ?  481 LEU B N   1 
ATOM   7656 C  CA  . LEU B 1 481 ? 52.23371  6.57938   -54.41072 1.000 23.21384  ?  481 LEU B CA  1 
ATOM   7657 C  C   . LEU B 1 481 ? 52.91896  6.40253   -55.75764 1.000 20.69478  ?  481 LEU B C   1 
ATOM   7658 O  O   . LEU B 1 481 ? 53.30849  5.28970   -56.13201 1.000 17.60009  ?  481 LEU B O   1 
ATOM   7659 C  CB  . LEU B 1 481 ? 50.72516  6.74425   -54.60109 1.000 16.36275  ?  481 LEU B CB  1 
ATOM   7660 C  CG  . LEU B 1 481 ? 49.82408  6.69910   -53.36776 1.000 14.68381  ?  481 LEU B CG  1 
ATOM   7661 C  CD1 . LEU B 1 481 ? 48.37894  6.93172   -53.77303 1.000 17.05097  ?  481 LEU B CD1 1 
ATOM   7662 C  CD2 . LEU B 1 481 ? 49.97438  5.37975   -52.62949 1.000 12.57976  ?  481 LEU B CD2 1 
ATOM   7663 N  N   . ALA B 1 482 ? 53.09062  7.50330   -56.49250 1.000 20.81664  ?  482 ALA B N   1 
ATOM   7664 C  CA  . ALA B 1 482 ? 53.75679  7.42680   -57.78937 1.000 19.97468  ?  482 ALA B CA  1 
ATOM   7665 C  C   . ALA B 1 482 ? 55.20203  6.95967   -57.64459 1.000 25.05909  ?  482 ALA B C   1 
ATOM   7666 O  O   . ALA B 1 482 ? 55.68738  6.15998   -58.45370 1.000 26.88549  ?  482 ALA B O   1 
ATOM   7667 C  CB  . ALA B 1 482 ? 53.69479  8.78095   -58.49371 1.000 17.40410  ?  482 ALA B CB  1 
ATOM   7668 N  N   . LEU B 1 483 ? 55.90629  7.45010   -56.62097 1.000 21.96022  ?  483 LEU B N   1 
ATOM   7669 C  CA  . LEU B 1 483 ? 57.29558  7.04820   -56.41101 1.000 18.91635  ?  483 LEU B CA  1 
ATOM   7670 C  C   . LEU B 1 483 ? 57.39881  5.57630   -56.02391 1.000 25.78828  ?  483 LEU B C   1 
ATOM   7671 O  O   . LEU B 1 483 ? 58.24605  4.84282   -56.54914 1.000 26.44136  ?  483 LEU B O   1 
ATOM   7672 C  CB  . LEU B 1 483 ? 57.93975  7.92989   -55.34170 1.000 18.75397  ?  483 LEU B CB  1 
ATOM   7673 C  CG  . LEU B 1 483 ? 58.27107  9.36445   -55.75115 1.000 14.90163  ?  483 LEU B CG  1 
ATOM   7674 C  CD1 . LEU B 1 483 ? 58.84861  10.13127  -54.57455 1.000 15.44065  ?  483 LEU B CD1 1 
ATOM   7675 C  CD2 . LEU B 1 483 ? 59.23819  9.36914   -56.92193 1.000 16.10675  ?  483 LEU B CD2 1 
ATOM   7676 N  N   . ASN B 1 484 ? 56.55050  5.12924   -55.09374 1.000 29.47546  ?  484 ASN B N   1 
ATOM   7677 C  CA  . ASN B 1 484 ? 56.55035  3.72787   -54.68980 1.000 28.03524  ?  484 ASN B CA  1 
ATOM   7678 C  C   . ASN B 1 484 ? 56.15699  2.81825   -55.84220 1.000 28.56888  ?  484 ASN B C   1 
ATOM   7679 O  O   . ASN B 1 484 ? 56.57153  1.65439   -55.88311 1.000 31.78630  ?  484 ASN B O   1 
ATOM   7680 C  CB  . ASN B 1 484 ? 55.60456  3.51955   -53.50556 1.000 26.95827  ?  484 ASN B CB  1 
ATOM   7681 C  CG  . ASN B 1 484 ? 56.12760  4.13676   -52.22447 1.000 31.04994  ?  484 ASN B CG  1 
ATOM   7682 O  OD1 . ASN B 1 484 ? 57.07611  4.91966   -52.24217 1.000 38.79123  ?  484 ASN B OD1 1 
ATOM   7683 N  ND2 . ASN B 1 484 ? 55.50903  3.78566   -51.10214 1.000 26.30023  ?  484 ASN B ND2 1 
ATOM   7684 N  N   . SER B 1 485 ? 55.35511  3.32593   -56.78192 1.000 26.18434  ?  485 SER B N   1 
ATOM   7685 C  CA  . SER B 1 485 ? 55.00548  2.53576   -57.95496 1.000 27.25360  ?  485 SER B CA  1 
ATOM   7686 C  C   . SER B 1 485 ? 56.23475  2.19056   -58.78459 1.000 32.31739  ?  485 SER B C   1 
ATOM   7687 O  O   . SER B 1 485 ? 56.25630  1.15625   -59.46183 1.000 37.08187  ?  485 SER B O   1 
ATOM   7688 C  CB  . SER B 1 485 ? 53.98410  3.28875   -58.80370 1.000 25.75077  ?  485 SER B CB  1 
ATOM   7689 O  OG  . SER B 1 485 ? 53.61387  2.51895   -59.92875 1.000 32.19825  ?  485 SER B OG  1 
ATOM   7690 N  N   . ILE B 1 486 ? 57.26102  3.03573   -58.74666 1.000 29.58677  ?  486 ILE B N   1 
ATOM   7691 C  CA  . ILE B 1 486 ? 58.50159  2.75485   -59.46136 1.000 24.92123  ?  486 ILE B CA  1 
ATOM   7692 C  C   . ILE B 1 486 ? 59.48871  1.99516   -58.58348 1.000 25.73055  ?  486 ILE B C   1 
ATOM   7693 O  O   . ILE B 1 486 ? 60.15358  1.06828   -59.05271 1.000 25.11465  ?  486 ILE B O   1 
ATOM   7694 C  CB  . ILE B 1 486 ? 59.11088  4.06692   -59.99412 1.000 19.87019  ?  486 ILE B CB  1 
ATOM   7695 C  CG1 . ILE B 1 486 ? 58.13758  4.74951   -60.95720 1.000 16.57469  ?  486 ILE B CG1 1 
ATOM   7696 C  CG2 . ILE B 1 486 ? 60.44389  3.80139   -60.67840 1.000 13.23250  ?  486 ILE B CG2 1 
ATOM   7697 C  CD1 . ILE B 1 486 ? 58.67328  6.02507   -61.56705 1.000 18.24260  ?  486 ILE B CD1 1 
ATOM   7698 N  N   . ARG B 1 487 ? 59.60158  2.36696   -57.30390 1.000 29.19477  ?  487 ARG B N   1 
ATOM   7699 C  CA  . ARG B 1 487 ? 60.53146  1.66736   -56.42095 1.000 23.25303  ?  487 ARG B CA  1 
ATOM   7700 C  C   . ARG B 1 487 ? 60.14929  0.20206   -56.26150 1.000 26.69879  ?  487 ARG B C   1 
ATOM   7701 O  O   . ARG B 1 487 ? 61.01307  -0.68140  -56.30718 1.000 31.78124  ?  487 ARG B O   1 
ATOM   7702 C  CB  . ARG B 1 487 ? 60.59466  2.34425   -55.05045 1.000 26.72020  ?  487 ARG B CB  1 
ATOM   7703 C  CG  . ARG B 1 487 ? 61.21641  1.44597   -53.98201 1.000 35.46991  ?  487 ARG B CG  1 
ATOM   7704 C  CD  . ARG B 1 487 ? 61.77555  2.21338   -52.79344 1.000 50.14649  ?  487 ARG B CD  1 
ATOM   7705 N  NE  . ARG B 1 487 ? 60.73697  2.71346   -51.90131 1.000 65.91180  ?  487 ARG B NE  1 
ATOM   7706 C  CZ  . ARG B 1 487 ? 60.93438  3.01915   -50.62590 1.000 74.42356  ?  487 ARG B CZ  1 
ATOM   7707 N  NH1 . ARG B 1 487 ? 62.11503  2.85538   -50.05069 1.000 60.65134  ?  487 ARG B NH1 1 
ATOM   7708 N  NH2 . ARG B 1 487 ? 59.92055  3.49412   -49.90758 1.000 67.83761  ?  487 ARG B NH2 1 
ATOM   7709 N  N   . TYR B 1 488 ? 58.86005  -0.07839  -56.08195 1.000 26.39365  ?  488 TYR B N   1 
ATOM   7710 C  CA  . TYR B 1 488 ? 58.38861  -1.43144  -55.82778 1.000 31.95775  ?  488 TYR B CA  1 
ATOM   7711 C  C   . TYR B 1 488 ? 57.92126  -2.13618  -57.09426 1.000 33.26652  ?  488 TYR B C   1 
ATOM   7712 O  O   . TYR B 1 488 ? 57.12862  -3.07975  -57.01490 1.000 38.88164  ?  488 TYR B O   1 
ATOM   7713 C  CB  . TYR B 1 488 ? 57.27775  -1.41026  -54.77851 1.000 26.67873  ?  488 TYR B CB  1 
ATOM   7714 C  CG  . TYR B 1 488 ? 57.74532  -0.85713  -53.45415 1.000 28.97230  ?  488 TYR B CG  1 
ATOM   7715 C  CD1 . TYR B 1 488 ? 58.48507  -1.63947  -52.57751 1.000 34.91235  ?  488 TYR B CD1 1 
ATOM   7716 C  CD2 . TYR B 1 488 ? 57.46523  0.45160   -53.08782 1.000 30.40885  ?  488 TYR B CD2 1 
ATOM   7717 C  CE1 . TYR B 1 488 ? 58.92376  -1.13753  -51.36863 1.000 34.36011  ?  488 TYR B CE1 1 
ATOM   7718 C  CE2 . TYR B 1 488 ? 57.89919  0.96263   -51.88033 1.000 37.13241  ?  488 TYR B CE2 1 
ATOM   7719 C  CZ  . TYR B 1 488 ? 58.62948  0.16399   -51.02603 1.000 34.19537  ?  488 TYR B CZ  1 
ATOM   7720 O  OH  . TYR B 1 488 ? 59.06261  0.66655   -49.82121 1.000 36.13782  ?  488 TYR B OH  1 
ATOM   7721 N  N   . SER B 1 489 ? 58.39596  -1.70076  -58.25736 1.000 26.27013  ?  489 SER B N   1 
ATOM   7722 C  CA  . SER B 1 489 ? 58.12793  -2.41547  -59.49277 1.000 24.52279  ?  489 SER B CA  1 
ATOM   7723 C  C   . SER B 1 489 ? 59.05094  -3.62731  -59.59557 1.000 27.11923  ?  489 SER B C   1 
ATOM   7724 O  O   . SER B 1 489 ? 59.84887  -3.91585  -58.69897 1.000 32.26358  ?  489 SER B O   1 
ATOM   7725 C  CB  . SER B 1 489 ? 58.30519  -1.49103  -60.69392 1.000 24.12818  ?  489 SER B CB  1 
ATOM   7726 O  OG  . SER B 1 489 ? 59.67521  -1.19780  -60.90447 1.000 26.55061  ?  489 SER B OG  1 
ATOM   7727 N  N   . ALA B 1 490 ? 58.94116  -4.35105  -60.70562 1.000 24.16226  ?  490 ALA B N   1 
ATOM   7728 C  CA  . ALA B 1 490 ? 59.81944  -5.47599  -60.98717 1.000 21.99327  ?  490 ALA B CA  1 
ATOM   7729 C  C   . ALA B 1 490 ? 60.98454  -5.09890  -61.89040 1.000 29.00681  ?  490 ALA B C   1 
ATOM   7730 O  O   . ALA B 1 490 ? 61.76498  -5.97699  -62.27203 1.000 29.21690  ?  490 ALA B O   1 
ATOM   7731 C  CB  . ALA B 1 490 ? 59.02497  -6.62284  -61.61613 1.000 22.89845  ?  490 ALA B CB  1 
ATOM   7732 N  N   . MET B 1 491 ? 61.11832  -3.82182  -62.24013 1.000 30.09176  ?  491 MET B N   1 
ATOM   7733 C  CA  . MET B 1 491 ? 62.21756  -3.38070  -63.08500 1.000 26.32583  ?  491 MET B CA  1 
ATOM   7734 C  C   . MET B 1 491 ? 63.55203  -3.53218  -62.36525 1.000 26.47869  ?  491 MET B C   1 
ATOM   7735 O  O   . MET B 1 491 ? 63.63651  -3.45903  -61.13685 1.000 22.37324  ?  491 MET B O   1 
ATOM   7736 C  CB  . MET B 1 491 ? 62.02450  -1.92312  -63.50256 1.000 26.15660  ?  491 MET B CB  1 
ATOM   7737 C  CG  . MET B 1 491 ? 61.02341  -1.71243  -64.62307 1.000 34.65887  ?  491 MET B CG  1 
ATOM   7738 S  SD  . MET B 1 491 ? 60.83387  0.03444   -65.02811 1.000 24.92198  ?  491 MET B SD  1 
ATOM   7739 C  CE  . MET B 1 491 ? 60.14799  0.65359   -63.49479 1.000 19.93812  ?  491 MET B CE  1 
ATOM   7740 N  N   . SER B 1 492 ? 64.60327  -3.74703  -63.15064 1.000 30.70338  ?  492 SER B N   1 
ATOM   7741 C  CA  . SER B 1 492 ? 65.94842  -3.80212  -62.60681 1.000 27.82165  ?  492 SER B CA  1 
ATOM   7742 C  C   . SER B 1 492 ? 66.34651  -2.43630  -62.04948 1.000 30.72491  ?  492 SER B C   1 
ATOM   7743 O  O   . SER B 1 492 ? 65.70498  -1.41489  -62.31057 1.000 33.55977  ?  492 SER B O   1 
ATOM   7744 C  CB  . SER B 1 492 ? 66.93701  -4.25399  -63.68008 1.000 28.16794  ?  492 SER B CB  1 
ATOM   7745 O  OG  . SER B 1 492 ? 66.79439  -3.47622  -64.85602 1.000 20.90167  ?  492 SER B OG  1 
ATOM   7746 N  N   . ASP B 1 493 ? 67.42471  -2.42765  -61.26164 1.000 35.30497  ?  493 ASP B N   1 
ATOM   7747 C  CA  . ASP B 1 493 ? 67.89354  -1.17647  -60.67312 1.000 35.70635  ?  493 ASP B CA  1 
ATOM   7748 C  C   . ASP B 1 493 ? 68.30874  -0.18057  -61.74846 1.000 31.77483  ?  493 ASP B C   1 
ATOM   7749 O  O   . ASP B 1 493 ? 68.09498  1.02859   -61.60026 1.000 30.64786  ?  493 ASP B O   1 
ATOM   7750 C  CB  . ASP B 1 493 ? 69.05059  -1.44451  -59.71095 1.000 34.31184  ?  493 ASP B CB  1 
ATOM   7751 C  CG  . ASP B 1 493 ? 68.58040  -1.96590  -58.36669 1.000 46.49834  ?  493 ASP B CG  1 
ATOM   7752 O  OD1 . ASP B 1 493 ? 67.36201  -2.19695  -58.20957 1.000 37.38169  ?  493 ASP B OD1 1 
ATOM   7753 O  OD2 . ASP B 1 493 ? 69.42727  -2.13736  -57.46475 1.000 43.49533  -1 493 ASP B OD2 1 
ATOM   7754 N  N   . THR B 1 494 ? 68.90949  -0.66798  -62.83655 1.000 31.64964  ?  494 THR B N   1 
ATOM   7755 C  CA  . THR B 1 494 ? 69.29095  0.22269   -63.92807 1.000 31.10637  ?  494 THR B CA  1 
ATOM   7756 C  C   . THR B 1 494 ? 68.06650  0.79699   -64.63567 1.000 32.56630  ?  494 THR B C   1 
ATOM   7757 O  O   . THR B 1 494 ? 68.06919  1.96652   -65.03837 1.000 30.75202  ?  494 THR B O   1 
ATOM   7758 C  CB  . THR B 1 494 ? 70.19634  -0.51328  -64.91834 1.000 32.03868  ?  494 THR B CB  1 
ATOM   7759 O  OG1 . THR B 1 494 ? 70.36822  0.28375   -66.09711 1.000 52.10629  ?  494 THR B OG1 1 
ATOM   7760 C  CG2 . THR B 1 494 ? 69.60627  -1.86589  -65.29853 1.000 26.35303  ?  494 THR B CG2 1 
ATOM   7761 N  N   . GLU B 1 495 ? 67.01104  -0.00657  -64.79676 1.000 30.64180  ?  495 GLU B N   1 
ATOM   7762 C  CA  . GLU B 1 495 ? 65.80733  0.46397   -65.47520 1.000 29.62494  ?  495 GLU B CA  1 
ATOM   7763 C  C   . GLU B 1 495 ? 64.97342  1.39376   -64.60226 1.000 25.03172  ?  495 GLU B C   1 
ATOM   7764 O  O   . GLU B 1 495 ? 64.27095  2.26588   -65.12946 1.000 26.97763  ?  495 GLU B O   1 
ATOM   7765 C  CB  . GLU B 1 495 ? 64.95744  -0.72525  -65.92577 1.000 31.78169  ?  495 GLU B CB  1 
ATOM   7766 C  CG  . GLU B 1 495 ? 65.50391  -1.46322  -67.13621 1.000 39.41901  ?  495 GLU B CG  1 
ATOM   7767 C  CD  . GLU B 1 495 ? 64.63878  -2.64256  -67.53178 1.000 40.81290  ?  495 GLU B CD  1 
ATOM   7768 O  OE1 . GLU B 1 495 ? 63.92856  -3.17476  -66.65453 1.000 33.49220  ?  495 GLU B OE1 1 
ATOM   7769 O  OE2 . GLU B 1 495 ? 64.66406  -3.03360  -68.71790 1.000 47.27965  -1 495 GLU B OE2 1 
ATOM   7770 N  N   . LYS B 1 496 ? 65.02933  1.21995   -63.27975 1.000 21.91649  ?  496 LYS B N   1 
ATOM   7771 C  CA  . LYS B 1 496 ? 64.22644  2.04911   -62.38678 1.000 22.29207  ?  496 LYS B CA  1 
ATOM   7772 C  C   . LYS B 1 496 ? 64.65099  3.51117   -62.44876 1.000 22.34800  ?  496 LYS B C   1 
ATOM   7773 O  O   . LYS B 1 496 ? 63.80426  4.40832   -62.38073 1.000 20.56662  ?  496 LYS B O   1 
ATOM   7774 C  CB  . LYS B 1 496 ? 64.31621  1.51852   -60.95583 1.000 19.65258  ?  496 LYS B CB  1 
ATOM   7775 C  CG  . LYS B 1 496 ? 63.43736  0.30441   -60.69650 1.000 23.00430  ?  496 LYS B CG  1 
ATOM   7776 C  CD  . LYS B 1 496 ? 63.65632  -0.26276  -59.30476 1.000 27.65478  ?  496 LYS B CD  1 
ATOM   7777 C  CE  . LYS B 1 496 ? 62.66982  -1.38154  -59.01058 1.000 26.61447  ?  496 LYS B CE  1 
ATOM   7778 N  NZ  . LYS B 1 496 ? 63.01915  -2.12649  -57.77045 1.000 28.82714  ?  496 LYS B NZ  1 
ATOM   7779 N  N   . VAL B 1 497 ? 65.95364  3.77241   -62.57564 1.000 23.86626  ?  497 VAL B N   1 
ATOM   7780 C  CA  . VAL B 1 497 ? 66.43258  5.15196   -62.64363 1.000 21.97878  ?  497 VAL B CA  1 
ATOM   7781 C  C   . VAL B 1 497 ? 65.89276  5.84298   -63.89169 1.000 24.71081  ?  497 VAL B C   1 
ATOM   7782 O  O   . VAL B 1 497 ? 65.39756  6.97494   -63.83252 1.000 26.51484  ?  497 VAL B O   1 
ATOM   7783 C  CB  . VAL B 1 497 ? 67.97051  5.18848   -62.59533 1.000 16.90781  ?  497 VAL B CB  1 
ATOM   7784 C  CG1 . VAL B 1 497 ? 68.46929  6.62639   -62.57626 1.000 18.51959  ?  497 VAL B CG1 1 
ATOM   7785 C  CG2 . VAL B 1 497 ? 68.47850  4.42734   -61.38171 1.000 18.91888  ?  497 VAL B CG2 1 
ATOM   7786 N  N   . ALA B 1 498 ? 65.97252  5.16770   -65.04138 1.000 22.09393  ?  498 ALA B N   1 
ATOM   7787 C  CA  . ALA B 1 498 ? 65.45323  5.74746   -66.27798 1.000 25.81550  ?  498 ALA B CA  1 
ATOM   7788 C  C   . ALA B 1 498 ? 63.93966  5.92250   -66.21823 1.000 30.47839  ?  498 ALA B C   1 
ATOM   7789 O  O   . ALA B 1 498 ? 63.39962  6.91921   -66.72214 1.000 36.22276  ?  498 ALA B O   1 
ATOM   7790 C  CB  . ALA B 1 498 ? 65.84594  4.87775   -67.47131 1.000 30.74177  ?  498 ALA B CB  1 
ATOM   7791 N  N   . ALA B 1 499 ? 63.23630  4.95626   -65.62042 1.000 28.57816  ?  499 ALA B N   1 
ATOM   7792 C  CA  . ALA B 1 499 ? 61.78996  5.08052   -65.47824 1.000 31.74198  ?  499 ALA B CA  1 
ATOM   7793 C  C   . ALA B 1 499 ? 61.42554  6.28004   -64.61464 1.000 25.62857  ?  499 ALA B C   1 
ATOM   7794 O  O   . ALA B 1 499 ? 60.50333  7.03796   -64.94425 1.000 27.90863  ?  499 ALA B O   1 
ATOM   7795 C  CB  . ALA B 1 499 ? 61.20971  3.79665   -64.88862 1.000 27.75859  ?  499 ALA B CB  1 
ATOM   7796 N  N   . LYS B 1 500 ? 62.14475  6.47363   -63.50671 1.000 19.37551  ?  500 LYS B N   1 
ATOM   7797 C  CA  . LYS B 1 500 ? 61.90536  7.64610   -62.67749 1.000 22.35442  ?  500 LYS B CA  1 
ATOM   7798 C  C   . LYS B 1 500 ? 62.25855  8.92802   -63.41530 1.000 27.33690  ?  500 LYS B C   1 
ATOM   7799 O  O   . LYS B 1 500 ? 61.61600  9.95376   -63.19591 1.000 27.40364  ?  500 LYS B O   1 
ATOM   7800 C  CB  . LYS B 1 500 ? 62.69105  7.55566   -61.36967 1.000 20.97791  ?  500 LYS B CB  1 
ATOM   7801 C  CG  . LYS B 1 500 ? 62.36181  8.67960   -60.39516 1.000 15.43466  ?  500 LYS B CG  1 
ATOM   7802 C  CD  . LYS B 1 500 ? 63.20238  8.61064   -59.13513 1.000 18.75932  ?  500 LYS B CD  1 
ATOM   7803 C  CE  . LYS B 1 500 ? 62.89369  9.77998   -58.21477 1.000 22.75306  ?  500 LYS B CE  1 
ATOM   7804 N  NZ  . LYS B 1 500 ? 63.72921  9.75491   -56.98324 1.000 41.78473  ?  500 LYS B NZ  1 
ATOM   7805 N  N   . ALA B 1 501 ? 63.26615  8.89417   -64.28969 1.000 24.54204  ?  501 ALA B N   1 
ATOM   7806 C  CA  . ALA B 1 501 ? 63.58870  10.07638  -65.08535 1.000 19.49681  ?  501 ALA B CA  1 
ATOM   7807 C  C   . ALA B 1 501 ? 62.43271  10.45026  -66.00847 1.000 24.40023  ?  501 ALA B C   1 
ATOM   7808 O  O   . ALA B 1 501 ? 62.03372  11.62111  -66.08667 1.000 30.39091  ?  501 ALA B O   1 
ATOM   7809 C  CB  . ALA B 1 501 ? 64.86595  9.83371   -65.88875 1.000 18.16464  ?  501 ALA B CB  1 
ATOM   7810 N  N   . LYS B 1 502 ? 61.87732  9.46018   -66.71338 1.000 25.35907  ?  502 LYS B N   1 
ATOM   7811 C  CA  . LYS B 1 502 ? 60.72483  9.72222   -67.57587 1.000 30.61636  ?  502 LYS B CA  1 
ATOM   7812 C  C   . LYS B 1 502 ? 59.54588  10.25161  -66.76551 1.000 28.19002  ?  502 LYS B C   1 
ATOM   7813 O  O   . LYS B 1 502 ? 58.88932  11.23448  -67.15114 1.000 25.79295  ?  502 LYS B O   1 
ATOM   7814 C  CB  . LYS B 1 502 ? 60.31530  8.45054   -68.32261 1.000 28.30150  ?  502 LYS B CB  1 
ATOM   7815 C  CG  . LYS B 1 502 ? 61.23507  8.01489   -69.45033 1.000 22.67768  ?  502 LYS B CG  1 
ATOM   7816 C  CD  . LYS B 1 502 ? 60.43332  7.26998   -70.51364 1.000 23.98590  ?  502 LYS B CD  1 
ATOM   7817 C  CE  . LYS B 1 502 ? 61.32043  6.45285   -71.43796 1.000 32.62961  ?  502 LYS B CE  1 
ATOM   7818 N  NZ  . LYS B 1 502 ? 61.74695  5.17133   -70.80819 1.000 35.39505  ?  502 LYS B NZ  1 
ATOM   7819 N  N   . TRP B 1 503 ? 59.26208  9.60209   -65.63308 1.000 25.30559  ?  503 TRP B N   1 
ATOM   7820 C  CA  . TRP B 1 503 ? 58.14127  10.02290  -64.80358 1.000 25.99037  ?  503 TRP B CA  1 
ATOM   7821 C  C   . TRP B 1 503 ? 58.35395  11.42783  -64.26047 1.000 30.56609  ?  503 TRP B C   1 
ATOM   7822 O  O   . TRP B 1 503 ? 57.40416  12.20611  -64.16322 1.000 32.30462  ?  503 TRP B O   1 
ATOM   7823 C  CB  . TRP B 1 503 ? 57.92276  9.03833   -63.65695 1.000 24.18120  ?  503 TRP B CB  1 
ATOM   7824 C  CG  . TRP B 1 503 ? 56.93474  9.54861   -62.65777 1.000 24.97165  ?  503 TRP B CG  1 
ATOM   7825 C  CD1 . TRP B 1 503 ? 55.57731  9.42541   -62.70995 1.000 25.42375  ?  503 TRP B CD1 1 
ATOM   7826 C  CD2 . TRP B 1 503 ? 57.22555  10.28576  -61.46470 1.000 19.42467  ?  503 TRP B CD2 1 
ATOM   7827 N  NE1 . TRP B 1 503 ? 55.00515  10.03275  -61.61837 1.000 22.93124  ?  503 TRP B NE1 1 
ATOM   7828 C  CE2 . TRP B 1 503 ? 55.99622  10.56920  -60.83889 1.000 22.90197  ?  503 TRP B CE2 1 
ATOM   7829 C  CE3 . TRP B 1 503 ? 58.40655  10.73079  -60.86392 1.000 18.81251  ?  503 TRP B CE3 1 
ATOM   7830 C  CZ2 . TRP B 1 503 ? 55.91433  11.27633  -59.64085 1.000 22.35300  ?  503 TRP B CZ2 1 
ATOM   7831 C  CZ3 . TRP B 1 503 ? 58.32289  11.43261  -59.67557 1.000 18.83521  ?  503 TRP B CZ3 1 
ATOM   7832 C  CH2 . TRP B 1 503 ? 57.08604  11.69748  -59.07614 1.000 16.52495  ?  503 TRP B CH2 1 
ATOM   7833 N  N   . THR B 1 504 ? 59.58878  11.76370  -63.88173 1.000 29.68464  ?  504 THR B N   1 
ATOM   7834 C  CA  . THR B 1 504 ? 59.88323  13.10139  -63.38241 1.000 25.01264  ?  504 THR B CA  1 
ATOM   7835 C  C   . THR B 1 504 ? 59.69368  14.14628  -64.47048 1.000 22.62274  ?  504 THR B C   1 
ATOM   7836 O  O   . THR B 1 504 ? 59.16878  15.23205  -64.20596 1.000 28.05614  ?  504 THR B O   1 
ATOM   7837 C  CB  . THR B 1 504 ? 61.30776  13.15606  -62.82694 1.000 26.03817  ?  504 THR B CB  1 
ATOM   7838 O  OG1 . THR B 1 504 ? 61.41923  12.27603  -61.70165 1.000 29.39426  ?  504 THR B OG1 1 
ATOM   7839 C  CG2 . THR B 1 504 ? 61.66117  14.57038  -62.38823 1.000 40.14953  ?  504 THR B CG2 1 
ATOM   7840 N  N   . THR B 1 505 ? 60.11656  13.84031  -65.69914 1.000 23.58981  ?  505 THR B N   1 
ATOM   7841 C  CA  . THR B 1 505 ? 59.87280  14.76145  -66.80599 1.000 26.44165  ?  505 THR B CA  1 
ATOM   7842 C  C   . THR B 1 505 ? 58.38085  15.03285  -66.96701 1.000 29.02022  ?  505 THR B C   1 
ATOM   7843 O  O   . THR B 1 505 ? 57.94063  16.19390  -66.99994 1.000 31.95885  ?  505 THR B O   1 
ATOM   7844 C  CB  . THR B 1 505 ? 60.45598  14.19266  -68.10067 1.000 28.31167  ?  505 THR B CB  1 
ATOM   7845 O  OG1 . THR B 1 505 ? 61.86341  13.97529  -67.94094 1.000 31.84018  ?  505 THR B OG1 1 
ATOM   7846 C  CG2 . THR B 1 505 ? 60.22127  15.15224  -69.25890 1.000 25.50899  ?  505 THR B CG2 1 
ATOM   7847 N  N   . GLN B 1 506 ? 57.58206  13.96402  -67.04202 1.000 30.77011  ?  506 GLN B N   1 
ATOM   7848 C  CA  . GLN B 1 506 ? 56.14370  14.14185  -67.22983 1.000 25.40503  ?  506 GLN B CA  1 
ATOM   7849 C  C   . GLN B 1 506 ? 55.50868  14.84754  -66.03477 1.000 26.06994  ?  506 GLN B C   1 
ATOM   7850 O  O   . GLN B 1 506 ? 54.62477  15.69593  -66.20183 1.000 24.21558  ?  506 GLN B O   1 
ATOM   7851 C  CB  . GLN B 1 506 ? 55.47572  12.79150  -67.48417 1.000 24.12489  ?  506 GLN B CB  1 
ATOM   7852 C  CG  . GLN B 1 506 ? 55.95229  12.10994  -68.75659 1.000 29.79911  ?  506 GLN B CG  1 
ATOM   7853 C  CD  . GLN B 1 506 ? 55.85602  13.01363  -69.97204 1.000 23.11535  ?  506 GLN B CD  1 
ATOM   7854 O  OE1 . GLN B 1 506 ? 56.86918  13.47424  -70.49837 1.000 18.54393  ?  506 GLN B OE1 1 
ATOM   7855 N  NE2 . GLN B 1 506 ? 54.63402  13.26924  -70.42569 1.000 19.89255  ?  506 GLN B NE2 1 
ATOM   7856 N  N   . TRP B 1 507 ? 55.95309  14.51339  -64.82172 1.000 28.63508  ?  507 TRP B N   1 
ATOM   7857 C  CA  . TRP B 1 507 ? 55.40821  15.11497  -63.61038 1.000 24.65449  ?  507 TRP B CA  1 
ATOM   7858 C  C   . TRP B 1 507 ? 55.71423  16.60346  -63.54355 1.000 28.19471  ?  507 TRP B C   1 
ATOM   7859 O  O   . TRP B 1 507 ? 54.85623  17.40029  -63.15034 1.000 28.97355  ?  507 TRP B O   1 
ATOM   7860 C  CB  . TRP B 1 507 ? 55.96983  14.38685  -62.38756 1.000 21.60362  ?  507 TRP B CB  1 
ATOM   7861 C  CG  . TRP B 1 507 ? 55.62624  15.00409  -61.06627 1.000 26.58010  ?  507 TRP B CG  1 
ATOM   7862 C  CD1 . TRP B 1 507 ? 56.30160  16.00393  -60.42667 1.000 29.38059  ?  507 TRP B CD1 1 
ATOM   7863 C  CD2 . TRP B 1 507 ? 54.53808  14.64285  -60.20739 1.000 28.48531  ?  507 TRP B CD2 1 
ATOM   7864 N  NE1 . TRP B 1 507 ? 55.69375  16.29576  -59.22989 1.000 24.94492  ?  507 TRP B NE1 1 
ATOM   7865 C  CE2 . TRP B 1 507 ? 54.60929  15.47366  -59.07097 1.000 29.43099  ?  507 TRP B CE2 1 
ATOM   7866 C  CE3 . TRP B 1 507 ? 53.50683  13.70254  -60.29184 1.000 21.58912  ?  507 TRP B CE3 1 
ATOM   7867 C  CZ2 . TRP B 1 507 ? 53.68887  15.39224  -58.02807 1.000 27.45547  ?  507 TRP B CZ2 1 
ATOM   7868 C  CZ3 . TRP B 1 507 ? 52.59508  13.62326  -59.25566 1.000 20.38365  ?  507 TRP B CZ3 1 
ATOM   7869 C  CH2 . TRP B 1 507 ? 52.69165  14.46285  -58.13918 1.000 25.16686  ?  507 TRP B CH2 1 
ATOM   7870 N  N   . ASP B 1 508 ? 56.93589  16.99599  -63.90870 1.000 27.08847  ?  508 ASP B N   1 
ATOM   7871 C  CA  . ASP B 1 508 ? 57.28165  18.41100  -63.92740 1.000 25.60471  ?  508 ASP B CA  1 
ATOM   7872 C  C   . ASP B 1 508 ? 56.46820  19.15900  -64.97222 1.000 29.78688  ?  508 ASP B C   1 
ATOM   7873 O  O   . ASP B 1 508 ? 55.99175  20.27086  -64.71276 1.000 25.40984  ?  508 ASP B O   1 
ATOM   7874 C  CB  . ASP B 1 508 ? 58.77834  18.58468  -64.17872 1.000 23.58802  ?  508 ASP B CB  1 
ATOM   7875 C  CG  . ASP B 1 508 ? 59.61668  18.18883  -62.98161 1.000 28.46071  ?  508 ASP B CG  1 
ATOM   7876 O  OD1 . ASP B 1 508 ? 59.11284  18.29664  -61.84303 1.000 28.47070  ?  508 ASP B OD1 1 
ATOM   7877 O  OD2 . ASP B 1 508 ? 60.77830  17.77313  -63.17764 1.000 33.31556  -1 508 ASP B OD2 1 
ATOM   7878 N  N   . LYS B 1 509 ? 56.28620  18.56366  -66.15547 1.000 30.21617  ?  509 LYS B N   1 
ATOM   7879 C  CA  . LYS B 1 509 ? 55.44272  19.20753  -67.15888 1.000 28.30973  ?  509 LYS B CA  1 
ATOM   7880 C  C   . LYS B 1 509 ? 54.01795  19.37934  -66.64257 1.000 27.74161  ?  509 LYS B C   1 
ATOM   7881 O  O   . LYS B 1 509 ? 53.40588  20.44137  -66.81816 1.000 26.32011  ?  509 LYS B O   1 
ATOM   7882 C  CB  . LYS B 1 509 ? 55.45738  18.39917  -68.45701 1.000 27.24438  ?  509 LYS B CB  1 
ATOM   7883 C  CG  . LYS B 1 509 ? 54.90147  19.14069  -69.66637 1.000 29.88345  ?  509 LYS B CG  1 
ATOM   7884 C  CD  . LYS B 1 509 ? 53.48349  18.70176  -70.00206 1.000 45.37209  ?  509 LYS B CD  1 
ATOM   7885 C  CE  . LYS B 1 509 ? 52.99192  19.36880  -71.27930 1.000 47.10802  ?  509 LYS B CE  1 
ATOM   7886 N  NZ  . LYS B 1 509 ? 51.68219  18.82279  -71.73000 1.000 35.63592  ?  509 LYS B NZ  1 
ATOM   7887 N  N   . PHE B 1 510 ? 53.48449  18.34775  -65.98433 1.000 31.10670  ?  510 PHE B N   1 
ATOM   7888 C  CA  . PHE B 1 510 ? 52.12934  18.41082  -65.44547 1.000 31.93359  ?  510 PHE B CA  1 
ATOM   7889 C  C   . PHE B 1 510 ? 52.00338  19.49447  -64.38112 1.000 30.51374  ?  510 PHE B C   1 
ATOM   7890 O  O   . PHE B 1 510 ? 51.05528  20.28941  -64.39765 1.000 26.49374  ?  510 PHE B O   1 
ATOM   7891 C  CB  . PHE B 1 510 ? 51.74306  17.04217  -64.88168 1.000 28.69593  ?  510 PHE B CB  1 
ATOM   7892 C  CG  . PHE B 1 510 ? 50.74567  17.09839  -63.75840 1.000 23.98286  ?  510 PHE B CG  1 
ATOM   7893 C  CD1 . PHE B 1 510 ? 49.42616  17.44416  -63.99986 1.000 31.13366  ?  510 PHE B CD1 1 
ATOM   7894 C  CD2 . PHE B 1 510 ? 51.12405  16.78037  -62.46347 1.000 14.63934  ?  510 PHE B CD2 1 
ATOM   7895 C  CE1 . PHE B 1 510 ? 48.50666  17.48870  -62.96883 1.000 29.65395  ?  510 PHE B CE1 1 
ATOM   7896 C  CE2 . PHE B 1 510 ? 50.20914  16.82074  -61.42901 1.000 16.01795  ?  510 PHE B CE2 1 
ATOM   7897 C  CZ  . PHE B 1 510 ? 48.89862  17.17614  -61.68203 1.000 25.09212  ?  510 PHE B CZ  1 
ATOM   7898 N  N   . VAL B 1 511 ? 52.95280  19.53819  -63.44319 1.000 34.57628  ?  511 VAL B N   1 
ATOM   7899 C  CA  . VAL B 1 511 ? 52.90758  20.53754  -62.37860 1.000 30.63124  ?  511 VAL B CA  1 
ATOM   7900 C  C   . VAL B 1 511 ? 52.98964  21.93738  -62.96931 1.000 29.48056  ?  511 VAL B C   1 
ATOM   7901 O  O   . VAL B 1 511 ? 52.22534  22.83472  -62.59440 1.000 28.41030  ?  511 VAL B O   1 
ATOM   7902 C  CB  . VAL B 1 511 ? 54.03208  20.29048  -61.35533 1.000 26.35056  ?  511 VAL B CB  1 
ATOM   7903 C  CG1 . VAL B 1 511 ? 54.13215  21.45558  -60.38179 1.000 23.74219  ?  511 VAL B CG1 1 
ATOM   7904 C  CG2 . VAL B 1 511 ? 53.79261  18.99295  -60.60139 1.000 24.43376  ?  511 VAL B CG2 1 
ATOM   7905 N  N   . LYS B 1 512 ? 53.90993  22.13892  -63.91611 1.000 36.11332  ?  512 LYS B N   1 
ATOM   7906 C  CA  . LYS B 1 512 ? 54.08409  23.45505  -64.51911 1.000 33.14238  ?  512 LYS B CA  1 
ATOM   7907 C  C   . LYS B 1 512 ? 52.81665  23.90240  -65.23622 1.000 27.64931  ?  512 LYS B C   1 
ATOM   7908 O  O   . LYS B 1 512 ? 52.34816  25.03113  -65.04527 1.000 26.37075  ?  512 LYS B O   1 
ATOM   7909 C  CB  . LYS B 1 512 ? 55.27396  23.42480  -65.47930 1.000 28.31339  ?  512 LYS B CB  1 
ATOM   7910 C  CG  . LYS B 1 512 ? 55.77598  24.78842  -65.91707 1.000 34.00260  ?  512 LYS B CG  1 
ATOM   7911 C  CD  . LYS B 1 512 ? 57.11974  24.66003  -66.61564 1.000 32.56858  ?  512 LYS B CD  1 
ATOM   7912 C  CE  . LYS B 1 512 ? 57.79141  26.00988  -66.78930 1.000 42.88789  ?  512 LYS B CE  1 
ATOM   7913 N  NZ  . LYS B 1 512 ? 59.21522  25.86108  -67.20237 1.000 54.94605  ?  512 LYS B NZ  1 
ATOM   7914 N  N   . THR B 1 513 ? 52.23167  23.01826  -66.05065 1.000 27.31591  ?  513 THR B N   1 
ATOM   7915 C  CA  . THR B 1 513 ? 51.03269  23.38848  -66.79639 1.000 24.87005  ?  513 THR B CA  1 
ATOM   7916 C  C   . THR B 1 513 ? 49.85665  23.66148  -65.86554 1.000 25.16288  ?  513 THR B C   1 
ATOM   7917 O  O   . THR B 1 513 ? 49.14075  24.65524  -66.03963 1.000 21.27578  ?  513 THR B O   1 
ATOM   7918 C  CB  . THR B 1 513 ? 50.67741  22.29255  -67.80086 1.000 25.85497  ?  513 THR B CB  1 
ATOM   7919 O  OG1 . THR B 1 513 ? 51.80411  22.03771  -68.64931 1.000 24.28492  ?  513 THR B OG1 1 
ATOM   7920 C  CG2 . THR B 1 513 ? 49.49345  22.72031  -68.65749 1.000 21.73029  ?  513 THR B CG2 1 
ATOM   7921 N  N   . SER B 1 514 ? 49.64535  22.80019  -64.86492 1.000 31.21715  ?  514 SER B N   1 
ATOM   7922 C  CA  . SER B 1 514 ? 48.51978  22.98958  -63.95481 1.000 28.28573  ?  514 SER B CA  1 
ATOM   7923 C  C   . SER B 1 514 ? 48.66834  24.27410  -63.14892 1.000 29.67199  ?  514 SER B C   1 
ATOM   7924 O  O   . SER B 1 514 ? 47.69576  25.01851  -62.96334 1.000 32.70840  ?  514 SER B O   1 
ATOM   7925 C  CB  . SER B 1 514 ? 48.39011  21.78137  -63.02826 1.000 29.76208  ?  514 SER B CB  1 
ATOM   7926 O  OG  . SER B 1 514 ? 48.23186  20.58495  -63.77151 1.000 28.85369  ?  514 SER B OG  1 
ATOM   7927 N  N   . VAL B 1 515 ? 49.87969  24.55728  -62.66631 1.000 34.19055  ?  515 VAL B N   1 
ATOM   7928 C  CA  . VAL B 1 515 ? 50.10241  25.78633  -61.91616 1.000 34.06396  ?  515 VAL B CA  1 
ATOM   7929 C  C   . VAL B 1 515 ? 49.90008  27.00410  -62.80672 1.000 32.05051  ?  515 VAL B C   1 
ATOM   7930 O  O   . VAL B 1 515 ? 49.26840  27.98141  -62.39851 1.000 38.40692  ?  515 VAL B O   1 
ATOM   7931 C  CB  . VAL B 1 515 ? 51.49714  25.76771  -61.26904 1.000 33.20135  ?  515 VAL B CB  1 
ATOM   7932 C  CG1 . VAL B 1 515 ? 51.87780  27.15484  -60.77884 1.000 33.18495  ?  515 VAL B CG1 1 
ATOM   7933 C  CG2 . VAL B 1 515 ? 51.50453  24.77971  -60.12031 1.000 36.65389  ?  515 VAL B CG2 1 
ATOM   7934 N  N   . GLU B 1 516 ? 50.41216  26.96972  -64.03908 1.000 34.25036  ?  516 GLU B N   1 
ATOM   7935 C  CA  . GLU B 1 516 ? 50.19118  28.10156  -64.93256 1.000 34.03120  ?  516 GLU B CA  1 
ATOM   7936 C  C   . GLU B 1 516 ? 48.71670  28.25926  -65.28400 1.000 28.73171  ?  516 GLU B C   1 
ATOM   7937 O  O   . GLU B 1 516 ? 48.27354  29.36610  -65.61002 1.000 33.15632  ?  516 GLU B O   1 
ATOM   7938 C  CB  . GLU B 1 516 ? 51.04049  27.95021  -66.19335 1.000 36.10524  ?  516 GLU B CB  1 
ATOM   7939 C  CG  . GLU B 1 516 ? 52.53293  28.10369  -65.93331 1.000 48.25953  ?  516 GLU B CG  1 
ATOM   7940 C  CD  . GLU B 1 516 ? 53.36997  27.96444  -67.18813 1.000 63.59962  ?  516 GLU B CD  1 
ATOM   7941 O  OE1 . GLU B 1 516 ? 52.78653  27.89105  -68.29025 1.000 59.12640  ?  516 GLU B OE1 1 
ATOM   7942 O  OE2 . GLU B 1 516 ? 54.61360  27.92730  -67.07003 1.000 57.10069  -1 516 GLU B OE2 1 
ATOM   7943 N  N   . GLY B 1 517 ? 47.94345  27.17278  -65.21915 1.000 25.57144  ?  517 GLY B N   1 
ATOM   7944 C  CA  . GLY B 1 517 ? 46.51378  27.27108  -65.45163 1.000 24.51558  ?  517 GLY B CA  1 
ATOM   7945 C  C   . GLY B 1 517 ? 45.70146  27.70442  -64.24939 1.000 29.14474  ?  517 GLY B C   1 
ATOM   7946 O  O   . GLY B 1 517 ? 44.55880  28.14253  -64.41674 1.000 30.93046  ?  517 GLY B O   1 
ATOM   7947 N  N   . LEU B 1 518 ? 46.25677  27.59174  -63.04133 1.000 32.54098  ?  518 LEU B N   1 
ATOM   7948 C  CA  . LEU B 1 518 ? 45.53044  27.96416  -61.83067 1.000 32.77495  ?  518 LEU B CA  1 
ATOM   7949 C  C   . LEU B 1 518 ? 46.09095  29.18635  -61.11543 1.000 35.50492  ?  518 LEU B C   1 
ATOM   7950 O  O   . LEU B 1 518 ? 45.32404  29.92755  -60.49729 1.000 29.87468  ?  518 LEU B O   1 
ATOM   7951 C  CB  . LEU B 1 518 ? 45.50230  26.78711  -60.84741 1.000 30.96612  ?  518 LEU B CB  1 
ATOM   7952 C  CG  . LEU B 1 518 ? 44.86191  25.50229  -61.37571 1.000 29.04058  ?  518 LEU B CG  1 
ATOM   7953 C  CD1 . LEU B 1 518 ? 45.00381  24.37869  -60.36385 1.000 24.27824  ?  518 LEU B CD1 1 
ATOM   7954 C  CD2 . LEU B 1 518 ? 43.40159  25.73528  -61.72402 1.000 26.84802  ?  518 LEU B CD2 1 
ATOM   7955 N  N   . LYS B 1 519 ? 47.39535  29.41100  -61.18325 1.000 38.86045  ?  519 LYS B N   1 
ATOM   7956 C  CA  . LYS B 1 519 ? 48.04506  30.51302  -60.47995 1.000 36.53499  ?  519 LYS B CA  1 
ATOM   7957 C  C   . LYS B 1 519 ? 47.81386  31.82438  -61.22333 1.000 46.94859  ?  519 LYS B C   1 
ATOM   7958 O  O   . LYS B 1 519 ? 47.99494  31.87832  -62.44423 1.000 46.02152  ?  519 LYS B O   1 
ATOM   7959 C  CB  . LYS B 1 519 ? 49.54324  30.24693  -60.34384 1.000 46.94134  ?  519 LYS B CB  1 
ATOM   7960 C  CG  . LYS B 1 519 ? 50.34047  31.37838  -59.71719 1.000 67.57040  ?  519 LYS B CG  1 
ATOM   7961 C  CD  . LYS B 1 519 ? 51.83419  31.18587  -59.94144 1.000 58.64289  ?  519 LYS B CD  1 
ATOM   7962 C  CE  . LYS B 1 519 ? 52.18050  31.24973  -61.42203 1.000 50.87437  ?  519 LYS B CE  1 
ATOM   7963 N  NZ  . LYS B 1 519 ? 53.61883  30.96581  -61.67259 1.000 43.60558  ?  519 LYS B NZ  1 
ATOM   7964 N  N   . PRO B 1 520 ? 47.41578  32.89250  -60.53022 1.000 49.08808  ?  520 PRO B N   1 
ATOM   7965 C  CA  . PRO B 1 520 ? 47.22036  34.19333  -61.18362 1.000 39.07038  ?  520 PRO B CA  1 
ATOM   7966 C  C   . PRO B 1 520 ? 48.53617  34.93773  -61.34250 1.000 49.85013  ?  520 PRO B C   1 
ATOM   7967 O  O   . PRO B 1 520 ? 49.09779  35.44930  -60.36867 1.000 66.12376  ?  520 PRO B O   1 
ATOM   7968 C  CB  . PRO B 1 520 ? 46.26639  34.92255  -60.22395 1.000 35.10863  ?  520 PRO B CB  1 
ATOM   7969 C  CG  . PRO B 1 520 ? 46.19955  34.07630  -58.97166 1.000 33.86416  ?  520 PRO B CG  1 
ATOM   7970 C  CD  . PRO B 1 520 ? 47.20291  32.97983  -59.08016 1.000 52.92058  ?  520 PRO B CD  1 
ATOM   7971 N  N   . HIS B 1 521 ? 49.02068  35.01712  -62.58024 1.000 55.47171  ?  521 HIS B N   1 
ATOM   7972 C  CA  . HIS B 1 521 ? 50.15658  35.87100  -62.93128 1.000 64.11045  ?  521 HIS B CA  1 
ATOM   7973 C  C   . HIS B 1 521 ? 50.38310  35.86690  -64.43829 1.000 45.56570  ?  521 HIS B C   1 
ATOM   7974 O  O   . HIS B 1 521 ? 50.20365  36.88744  -65.10193 1.000 33.34666  ?  521 HIS B O   1 
ATOM   7975 C  CB  . HIS B 1 521 ? 51.43845  35.43541  -62.21402 1.000 71.32487  ?  521 HIS B CB  1 
ATOM   7976 C  CG  . HIS B 1 521 ? 52.28698  36.58319  -61.75998 1.000 80.30596  ?  521 HIS B CG  1 
ATOM   7977 N  ND1 . HIS B 1 521 ? 51.78443  37.62706  -61.01284 1.000 52.11494  ?  521 HIS B ND1 1 
ATOM   7978 C  CD2 . HIS B 1 521 ? 53.59874  36.85762  -61.95407 1.000 85.69846  ?  521 HIS B CD2 1 
ATOM   7979 C  CE1 . HIS B 1 521 ? 52.75048  38.49248  -60.76253 1.000 68.37376  ?  521 HIS B CE1 1 
ATOM   7980 N  NE2 . HIS B 1 521 ? 53.86173  38.04923  -61.32236 1.000 88.56646  ?  521 HIS B NE2 1 
HETATM 7981 C  C1  . NAG C 2 .   ? 48.54686  14.42135  -16.52104 1.000 48.57162  ?  1   NAG C C1  1 
HETATM 7982 C  C2  . NAG C 2 .   ? 48.37257  15.88907  -16.11647 1.000 46.27202  ?  1   NAG C C2  1 
HETATM 7983 C  C3  . NAG C 2 .   ? 49.73047  16.58060  -16.20650 1.000 53.36656  ?  1   NAG C C3  1 
HETATM 7984 C  C4  . NAG C 2 .   ? 50.75178  15.84076  -15.34552 1.000 64.23153  ?  1   NAG C C4  1 
HETATM 7985 C  C5  . NAG C 2 .   ? 50.77778  14.35239  -15.73225 1.000 49.05580  ?  1   NAG C C5  1 
HETATM 7986 C  C6  . NAG C 2 .   ? 51.66049  13.47814  -14.86779 1.000 51.52997  ?  1   NAG C C6  1 
HETATM 7987 C  C7  . NAG C 2 .   ? 46.09907  16.71272  -16.57843 1.000 27.48506  ?  1   NAG C C7  1 
HETATM 7988 C  C8  . NAG C 2 .   ? 45.24302  17.43237  -17.58884 1.000 23.50118  ?  1   NAG C C8  1 
HETATM 7989 N  N2  . NAG C 2 .   ? 47.38691  16.54601  -16.93446 1.000 26.75114  ?  1   NAG C N2  1 
HETATM 7990 O  O3  . NAG C 2 .   ? 49.57222  17.91786  -15.81270 1.000 54.30824  ?  1   NAG C O3  1 
HETATM 7991 O  O4  . NAG C 2 .   ? 51.99530  16.47779  -15.54443 1.000 68.25787  ?  1   NAG C O4  1 
HETATM 7992 O  O5  . NAG C 2 .   ? 49.47148  13.82158  -15.64690 1.000 40.98971  ?  1   NAG C O5  1 
HETATM 7993 O  O6  . NAG C 2 .   ? 51.14311  13.44257  -13.55816 1.000 45.77611  ?  1   NAG C O6  1 
HETATM 7994 O  O7  . NAG C 2 .   ? 45.63305  16.31593  -15.52082 1.000 35.74042  ?  1   NAG C O7  1 
HETATM 7995 C  C1  . NAG C 2 .   ? 52.56682  16.78231  -14.25218 1.000 72.07901  ?  2   NAG C C1  1 
HETATM 7996 C  C2  . NAG C 2 .   ? 54.07634  16.99448  -14.42666 1.000 77.15053  ?  2   NAG C C2  1 
HETATM 7997 C  C3  . NAG C 2 .   ? 54.71830  17.41051  -13.10230 1.000 82.19153  ?  2   NAG C C3  1 
HETATM 7998 C  C4  . NAG C 2 .   ? 53.91750  18.46303  -12.33492 1.000 79.03689  ?  2   NAG C C4  1 
HETATM 7999 C  C5  . NAG C 2 .   ? 52.42067  18.12352  -12.36251 1.000 70.90601  ?  2   NAG C C5  1 
HETATM 8000 C  C6  . NAG C 2 .   ? 51.51159  19.14341  -11.70974 1.000 71.29055  ?  2   NAG C C6  1 
HETATM 8001 C  C7  . NAG C 2 .   ? 55.07494  15.53151  -16.15402 1.000 86.27153  ?  2   NAG C C7  1 
HETATM 8002 C  C8  . NAG C 2 .   ? 55.67389  14.16388  -16.37595 1.000 80.75691  ?  2   NAG C C8  1 
HETATM 8003 N  N2  . NAG C 2 .   ? 54.67685  15.77363  -14.89255 1.000 84.54755  ?  2   NAG C N2  1 
HETATM 8004 O  O3  . NAG C 2 .   ? 56.02151  17.85362  -13.38174 1.000 83.02030  ?  2   NAG C O3  1 
HETATM 8005 O  O4  . NAG C 2 .   ? 54.41960  18.42200  -11.01838 1.000 82.77080  ?  2   NAG C O4  1 
HETATM 8006 O  O5  . NAG C 2 .   ? 52.01344  17.95363  -13.70279 1.000 65.48329  ?  2   NAG C O5  1 
HETATM 8007 O  O6  . NAG C 2 .   ? 51.32513  20.24185  -12.57056 1.000 70.96892  ?  2   NAG C O6  1 
HETATM 8008 O  O7  . NAG C 2 .   ? 54.96844  16.34134  -17.06292 1.000 83.03097  ?  2   NAG C O7  1 
HETATM 8009 C  C1  . BMA C 2 .   ? 54.88818  19.72041  -10.59770 1.000 86.93973  ?  3   BMA C C1  1 
HETATM 8010 C  C2  . BMA C 2 .   ? 55.26770  19.59484  -9.12892  1.000 85.63996  ?  3   BMA C C2  1 
HETATM 8011 C  C3  . BMA C 2 .   ? 55.88502  20.91131  -8.59618  1.000 92.16137  ?  3   BMA C C3  1 
HETATM 8012 C  C4  . BMA C 2 .   ? 56.40178  21.91912  -9.65282  1.000 95.36372  ?  3   BMA C C4  1 
HETATM 8013 C  C5  . BMA C 2 .   ? 56.59308  21.39806  -11.08553 1.000 87.85485  ?  3   BMA C C5  1 
HETATM 8014 C  C6  . BMA C 2 .   ? 58.03520  21.45392  -11.59870 1.000 92.20155  ?  3   BMA C C6  1 
HETATM 8015 O  O2  . BMA C 2 .   ? 56.12817  18.49574  -8.98762  1.000 77.61891  ?  3   BMA C O2  1 
HETATM 8016 O  O3  . BMA C 2 .   ? 56.86650  20.52849  -7.66312  1.000 88.46607  ?  3   BMA C O3  1 
HETATM 8017 O  O4  . BMA C 2 .   ? 55.45415  22.97122  -9.63944  1.000 59.00359  ?  3   BMA C O4  1 
HETATM 8018 O  O5  . BMA C 2 .   ? 56.00561  20.13314  -11.35642 1.000 77.97188  ?  3   BMA C O5  1 
HETATM 8019 O  O6  . BMA C 2 .   ? 58.79106  20.35065  -11.14102 1.000 99.37177  ?  3   BMA C O6  1 
HETATM 8020 C  C1  . MAN C 2 .   ? 59.34662  19.64731  -12.28520 1.000 106.13304 ?  4   MAN C C1  1 
HETATM 8021 C  C2  . MAN C 2 .   ? 60.28786  18.55483  -11.75574 1.000 97.37931  ?  4   MAN C C2  1 
HETATM 8022 C  C3  . MAN C 2 .   ? 61.53640  19.18032  -11.14784 1.000 105.65656 ?  4   MAN C C3  1 
HETATM 8023 C  C4  . MAN C 2 .   ? 62.25559  20.00232  -12.20622 1.000 104.43209 ?  4   MAN C C4  1 
HETATM 8024 C  C5  . MAN C 2 .   ? 61.29979  21.07729  -12.73487 1.000 118.23718 ?  4   MAN C C5  1 
HETATM 8025 C  C6  . MAN C 2 .   ? 61.88216  21.79630  -13.93504 1.000 122.88390 ?  4   MAN C C6  1 
HETATM 8026 O  O2  . MAN C 2 .   ? 60.60634  17.73037  -12.85066 1.000 90.55274  ?  4   MAN C O2  1 
HETATM 8027 O  O3  . MAN C 2 .   ? 62.34285  18.13862  -10.65074 1.000 107.99379 ?  4   MAN C O3  1 
HETATM 8028 O  O4  . MAN C 2 .   ? 63.39195  20.56820  -11.58806 1.000 101.50585 ?  4   MAN C O4  1 
HETATM 8029 O  O5  . MAN C 2 .   ? 60.05417  20.52043  -13.14682 1.000 121.68528 ?  4   MAN C O5  1 
HETATM 8030 O  O6  . MAN C 2 .   ? 61.05551  21.57933  -15.05349 1.000 126.87808 ?  4   MAN C O6  1 
HETATM 8031 C  C1  . NAG D 3 .   ? 8.00663   -2.31601  -10.62689 1.000 40.12870  ?  601 NAG A C1  1 
HETATM 8032 C  C2  . NAG D 3 .   ? 6.82907   -2.81683  -9.78038  1.000 30.79888  ?  601 NAG A C2  1 
HETATM 8033 C  C3  . NAG D 3 .   ? 7.09668   -2.52245  -8.30646  1.000 26.35055  ?  601 NAG A C3  1 
HETATM 8034 C  C4  . NAG D 3 .   ? 8.46223   -3.05776  -7.88808  1.000 34.32819  ?  601 NAG A C4  1 
HETATM 8035 C  C5  . NAG D 3 .   ? 9.53281   -2.50830  -8.83674  1.000 45.52845  ?  601 NAG A C5  1 
HETATM 8036 C  C6  . NAG D 3 .   ? 10.93805  -2.98063  -8.53023  1.000 42.09142  ?  601 NAG A C6  1 
HETATM 8037 C  C7  . NAG D 3 .   ? 4.49536   -2.86378  -10.58035 1.000 39.52963  ?  601 NAG A C7  1 
HETATM 8038 C  C8  . NAG D 3 .   ? 3.33127   -1.98874  -10.97896 1.000 20.59150  ?  601 NAG A C8  1 
HETATM 8039 N  N2  . NAG D 3 .   ? 5.60082   -2.19713  -10.19987 1.000 39.25880  ?  601 NAG A N2  1 
HETATM 8040 O  O3  . NAG D 3 .   ? 6.05526   -3.09152  -7.55851  1.000 23.37631  ?  601 NAG A O3  1 
HETATM 8041 O  O4  . NAG D 3 .   ? 8.68556   -2.65002  -6.55853  1.000 36.17901  ?  601 NAG A O4  1 
HETATM 8042 O  O5  . NAG D 3 .   ? 9.20319   -2.89099  -10.15581 1.000 57.39872  ?  601 NAG A O5  1 
HETATM 8043 O  O6  . NAG D 3 .   ? 11.82897  -2.50805  -9.51388  1.000 36.60053  ?  601 NAG A O6  1 
HETATM 8044 O  O7  . NAG D 3 .   ? 4.41968   -4.08383  -10.60582 1.000 36.84239  ?  601 NAG A O7  1 
HETATM 8045 C  C1  . NAG E 3 .   ? 28.39320  -27.42955 -46.67285 1.000 33.31416  ?  602 NAG A C1  1 
HETATM 8046 C  C2  . NAG E 3 .   ? 29.09389  -27.93616 -45.40399 1.000 31.12555  ?  602 NAG A C2  1 
HETATM 8047 C  C3  . NAG E 3 .   ? 28.93979  -29.45272 -45.31780 1.000 36.76367  ?  602 NAG A C3  1 
HETATM 8048 C  C4  . NAG E 3 .   ? 27.46456  -29.83422 -45.37898 1.000 33.44422  ?  602 NAG A C4  1 
HETATM 8049 C  C5  . NAG E 3 .   ? 26.83087  -29.22389 -46.63318 1.000 39.73401  ?  602 NAG A C5  1 
HETATM 8050 C  C6  . NAG E 3 .   ? 25.34177  -29.46664 -46.73351 1.000 42.91236  ?  602 NAG A C6  1 
HETATM 8051 C  C7  . NAG E 3 .   ? 31.12510  -27.11646 -44.27205 1.000 32.12005  ?  602 NAG A C7  1 
HETATM 8052 C  C8  . NAG E 3 .   ? 32.58401  -26.78926 -44.47389 1.000 27.13834  ?  602 NAG A C8  1 
HETATM 8053 N  N2  . NAG E 3 .   ? 30.48443  -27.56532 -45.36949 1.000 30.30906  ?  602 NAG A N2  1 
HETATM 8054 O  O3  . NAG E 3 .   ? 29.54666  -29.88400 -44.12838 1.000 40.07696  ?  602 NAG A O3  1 
HETATM 8055 O  O4  . NAG E 3 .   ? 27.38543  -31.24104 -45.38955 1.000 22.70456  ?  602 NAG A O4  1 
HETATM 8056 O  O5  . NAG E 3 .   ? 27.04284  -27.82741 -46.63626 1.000 38.85513  ?  602 NAG A O5  1 
HETATM 8057 O  O6  . NAG E 3 .   ? 24.69735  -28.27366 -47.11402 1.000 32.89627  ?  602 NAG A O6  1 
HETATM 8058 O  O7  . NAG E 3 .   ? 30.58819  -26.97901 -43.18181 1.000 30.88480  ?  602 NAG A O7  1 
HETATM 8059 C  C1  . NAG F 3 .   ? 4.52794   4.35608   -34.10299 1.000 39.95618  ?  603 NAG A C1  1 
HETATM 8060 C  C2  . NAG F 3 .   ? 5.22652   3.83777   -35.36823 1.000 35.83263  ?  603 NAG A C2  1 
HETATM 8061 C  C3  . NAG F 3 .   ? 4.55204   4.38192   -36.62257 1.000 28.38697  ?  603 NAG A C3  1 
HETATM 8062 C  C4  . NAG F 3 .   ? 3.05886   4.11152   -36.54063 1.000 21.37251  ?  603 NAG A C4  1 
HETATM 8063 C  C5  . NAG F 3 .   ? 2.53318   4.83052   -35.30032 1.000 20.24661  ?  603 NAG A C5  1 
HETATM 8064 C  C6  . NAG F 3 .   ? 1.03428   4.77042   -35.12779 1.000 27.65845  ?  603 NAG A C6  1 
HETATM 8065 C  C7  . NAG F 3 .   ? 7.60125   3.39278   -34.95043 1.000 30.91619  ?  603 NAG A C7  1 
HETATM 8066 C  C8  . NAG F 3 .   ? 8.98246   3.98981   -35.03242 1.000 30.18354  ?  603 NAG A C8  1 
HETATM 8067 N  N2  . NAG F 3 .   ? 6.61385   4.20685   -35.35575 1.000 25.54841  ?  603 NAG A N2  1 
HETATM 8068 O  O3  . NAG F 3 .   ? 5.14485   3.77560   -37.74000 1.000 17.86503  ?  603 NAG A O3  1 
HETATM 8069 O  O4  . NAG F 3 .   ? 2.48346   4.59657   -37.72560 1.000 18.17236  ?  603 NAG A O4  1 
HETATM 8070 O  O5  . NAG F 3 .   ? 3.12873   4.20283   -34.18981 1.000 25.73089  ?  603 NAG A O5  1 
HETATM 8071 O  O6  . NAG F 3 .   ? 0.72353   3.78440   -34.17284 1.000 34.31994  ?  603 NAG A O6  1 
HETATM 8072 O  O7  . NAG F 3 .   ? 7.41010   2.25662   -34.54249 1.000 29.24955  ?  603 NAG A O7  1 
HETATM 8073 C  C1  . EDO G 4 .   ? 23.48132  3.29289   -40.95359 1.000 19.19786  ?  604 EDO A C1  1 
HETATM 8074 O  O1  . EDO G 4 .   ? 23.78960  2.54904   -42.11013 1.000 24.58630  ?  604 EDO A O1  1 
HETATM 8075 C  C2  . EDO G 4 .   ? 23.05744  2.36934   -39.84212 1.000 15.36520  ?  604 EDO A C2  1 
HETATM 8076 O  O2  . EDO G 4 .   ? 24.19508  1.72733   -39.31311 1.000 22.85487  ?  604 EDO A O2  1 
HETATM 8077 C  C1  . EDO H 4 .   ? 30.93710  -14.67601 -46.37182 1.000 32.57776  ?  605 EDO A C1  1 
HETATM 8078 O  O1  . EDO H 4 .   ? 30.44190  -13.60908 -45.59474 1.000 18.38813  ?  605 EDO A O1  1 
HETATM 8079 C  C2  . EDO H 4 .   ? 32.44368  -14.70013 -46.30301 1.000 31.18838  ?  605 EDO A C2  1 
HETATM 8080 O  O2  . EDO H 4 .   ? 32.94381  -15.76631 -47.07973 1.000 18.97170  ?  605 EDO A O2  1 
HETATM 8081 C  C1  . EDO I 4 .   ? 28.64834  -11.53145 -43.81928 1.000 17.92867  ?  606 EDO A C1  1 
HETATM 8082 O  O1  . EDO I 4 .   ? 28.00104  -12.07807 -44.94609 1.000 20.34685  ?  606 EDO A O1  1 
HETATM 8083 C  C2  . EDO I 4 .   ? 27.79176  -10.44467 -43.22430 1.000 14.00842  ?  606 EDO A C2  1 
HETATM 8084 O  O2  . EDO I 4 .   ? 26.50057  -10.95344 -42.98174 1.000 16.30319  ?  606 EDO A O2  1 
HETATM 8085 ZN ZN  . ZN  J 5 .   ? 28.91473  5.28617   -24.58885 1.000 64.07445  ?  607 ZN  A ZN  1 
HETATM 8086 N  N1  . DCF K 6 .   ? 25.04324  6.37249   -25.98880 1.000 21.58101  ?  608 DCF A N1  1 
HETATM 8087 C  C2  . DCF K 6 .   ? 24.38612  7.38894   -25.48605 1.000 21.42154  ?  608 DCF A C2  1 
HETATM 8088 N  N3  . DCF K 6 .   ? 24.99682  8.59226   -25.72739 1.000 23.97008  ?  608 DCF A N3  1 
HETATM 8089 C  C9  . DCF K 6 .   ? 26.14813  6.93934   -26.59504 1.000 29.73734  ?  608 DCF A C9  1 
HETATM 8090 C  C10 . DCF K 6 .   ? 26.13661  8.30490   -26.44488 1.000 28.73730  ?  608 DCF A C10 1 
HETATM 8091 N  N4  . DCF K 6 .   ? 26.97134  9.31791   -26.84482 1.000 25.98595  ?  608 DCF A N4  1 
HETATM 8092 C  C5  . DCF K 6 .   ? 28.01727  9.06410   -27.53691 1.000 26.15663  ?  608 DCF A C5  1 
HETATM 8093 N  N6  . DCF K 6 .   ? 28.50521  8.00245   -28.18594 1.000 32.56013  ?  608 DCF A N6  1 
HETATM 8094 C  C7  . DCF K 6 .   ? 27.75032  6.80378   -28.52285 1.000 24.48192  ?  608 DCF A C7  1 
HETATM 8095 C  C8  . DCF K 6 .   ? 27.17755  6.10462   -27.29850 1.000 27.42516  ?  608 DCF A C8  1 
HETATM 8096 O  O8  . DCF K 6 .   ? 28.25373  5.74529   -26.43563 1.000 21.68663  ?  608 DCF A O8  1 
HETATM 8097 C  C2S . DCF K 6 .   ? 23.46851  10.54393  -26.18098 1.000 26.48079  ?  608 DCF A C2S 1 
HETATM 8098 C  C3S . DCF K 6 .   ? 22.23230  10.62678  -25.29107 1.000 26.40976  ?  608 DCF A C3S 1 
HETATM 8099 O  O3S . DCF K 6 .   ? 21.51982  11.84262  -25.52255 1.000 26.56714  ?  608 DCF A O3S 1 
HETATM 8100 O  O5S . DCF K 6 .   ? 22.59165  9.96742   -21.56686 1.000 29.94037  ?  608 DCF A O5S 1 
HETATM 8101 C  C5S . DCF K 6 .   ? 21.92291  10.05133  -22.81929 1.000 31.03587  ?  608 DCF A C5S 1 
HETATM 8102 C  C4S . DCF K 6 .   ? 22.82572  10.62294  -23.88800 1.000 27.58690  ?  608 DCF A C4S 1 
HETATM 8103 O  O4S . DCF K 6 .   ? 24.00947  9.81151   -23.98997 1.000 19.91781  ?  608 DCF A O4S 1 
HETATM 8104 C  C1S . DCF K 6 .   ? 24.55194  9.93054   -25.29606 1.000 26.34629  ?  608 DCF A C1S 1 
HETATM 8105 C  C1  . NAG L 3 .   ? 39.47136  -2.01228  -84.34710 1.000 37.79073  ?  601 NAG B C1  1 
HETATM 8106 C  C2  . NAG L 3 .   ? 39.17788  -1.26347  -85.65878 1.000 35.02967  ?  601 NAG B C2  1 
HETATM 8107 C  C3  . NAG L 3 .   ? 40.26861  -1.54277  -86.69563 1.000 29.92724  ?  601 NAG B C3  1 
HETATM 8108 C  C4  . NAG L 3 .   ? 41.64665  -1.29445  -86.09114 1.000 34.47581  ?  601 NAG B C4  1 
HETATM 8109 C  C5  . NAG L 3 .   ? 41.78151  -2.07144  -84.77445 1.000 37.63596  ?  601 NAG B C5  1 
HETATM 8110 C  C6  . NAG L 3 .   ? 43.11330  -1.89139  -84.08025 1.000 39.34650  ?  601 NAG B C6  1 
HETATM 8111 C  C7  . NAG L 3 .   ? 37.13634  -2.55991  -86.58693 1.000 42.88678  ?  601 NAG B C7  1 
HETATM 8112 C  C8  . NAG L 3 .   ? 37.79649  -3.92173  -86.63882 1.000 39.70272  ?  601 NAG B C8  1 
HETATM 8113 N  N2  . NAG L 3 .   ? 37.82594  -1.47267  -86.14941 1.000 34.19778  ?  601 NAG B N2  1 
HETATM 8114 O  O3  . NAG L 3 .   ? 40.02324  -0.72844  -87.81052 1.000 39.32146  ?  601 NAG B O3  1 
HETATM 8115 O  O4  . NAG L 3 .   ? 42.59592  -1.71075  -87.04533 1.000 31.08450  ?  601 NAG B O4  1 
HETATM 8116 O  O5  . NAG L 3 .   ? 40.75669  -1.66818  -83.88710 1.000 35.41860  ?  601 NAG B O5  1 
HETATM 8117 O  O6  . NAG L 3 .   ? 43.27447  -0.54253  -83.71037 1.000 54.18842  ?  601 NAG B O6  1 
HETATM 8118 O  O7  . NAG L 3 .   ? 35.97453  -2.45534  -86.94946 1.000 55.55405  ?  601 NAG B O7  1 
HETATM 8119 C  C1  . NAG M 3 .   ? 26.25430  23.70893  -44.88577 1.000 29.67516  ?  602 NAG B C1  1 
HETATM 8120 C  C2  . NAG M 3 .   ? 27.54214  24.21489  -45.55644 1.000 30.27017  ?  602 NAG B C2  1 
HETATM 8121 C  C3  . NAG M 3 .   ? 27.55965  25.74547  -45.57557 1.000 26.04484  ?  602 NAG B C3  1 
HETATM 8122 C  C4  . NAG M 3 .   ? 26.27658  26.27025  -46.21293 1.000 23.73614  ?  602 NAG B C4  1 
HETATM 8123 C  C5  . NAG M 3 .   ? 25.04974  25.63358  -45.54497 1.000 25.46308  ?  602 NAG B C5  1 
HETATM 8124 C  C6  . NAG M 3 .   ? 23.74251  26.04076  -46.18769 1.000 33.79593  ?  602 NAG B C6  1 
HETATM 8125 C  C7  . NAG M 3 .   ? 29.36281  23.60300  -43.81916 1.000 28.25503  ?  602 NAG B C7  1 
HETATM 8126 C  C8  . NAG M 3 .   ? 28.76480  24.36877  -42.65782 1.000 37.64890  ?  602 NAG B C8  1 
HETATM 8127 N  N2  . NAG M 3 .   ? 28.75309  23.60605  -45.03269 1.000 21.80568  ?  602 NAG B N2  1 
HETATM 8128 O  O3  . NAG M 3 .   ? 28.70394  26.15812  -46.27322 1.000 23.51185  ?  602 NAG B O3  1 
HETATM 8129 O  O4  . NAG M 3 .   ? 26.27804  27.67241  -46.06816 1.000 29.26745  ?  602 NAG B O4  1 
HETATM 8130 O  O5  . NAG M 3 .   ? 25.14779  24.22250  -45.59160 1.000 27.99775  ?  602 NAG B O5  1 
HETATM 8131 O  O6  . NAG M 3 .   ? 22.88484  24.92692  -46.26581 1.000 35.38041  ?  602 NAG B O6  1 
HETATM 8132 O  O7  . NAG M 3 .   ? 30.40400  22.98662  -43.64967 1.000 31.46363  ?  602 NAG B O7  1 
HETATM 8133 C  C1  . NAG N 3 .   ? 20.40899  -8.88458  -70.05164 1.000 31.35770  ?  603 NAG B C1  1 
HETATM 8134 C  C2  . NAG N 3 .   ? 19.95998  -8.43820  -68.64868 1.000 30.54165  ?  603 NAG B C2  1 
HETATM 8135 C  C3  . NAG N 3 .   ? 18.62438  -9.07516  -68.26892 1.000 34.03626  ?  603 NAG B C3  1 
HETATM 8136 C  C4  . NAG N 3 .   ? 17.60028  -8.83230  -69.36794 1.000 28.43924  ?  603 NAG B C4  1 
HETATM 8137 C  C5  . NAG N 3 .   ? 18.16598  -9.40903  -70.66596 1.000 29.46275  ?  603 NAG B C5  1 
HETATM 8138 C  C6  . NAG N 3 .   ? 17.21750  -9.31447  -71.84039 1.000 42.19797  ?  603 NAG B C6  1 
HETATM 8139 C  C7  . NAG N 3 .   ? 21.89253  -7.89633  -67.23602 1.000 30.53099  ?  603 NAG B C7  1 
HETATM 8140 C  C8  . NAG N 3 .   ? 22.84491  -8.44147  -66.20222 1.000 41.61919  ?  603 NAG B C8  1 
HETATM 8141 N  N2  . NAG N 3 .   ? 20.95821  -8.76143  -67.66555 1.000 21.89793  ?  603 NAG B N2  1 
HETATM 8142 O  O3  . NAG N 3 .   ? 18.21226  -8.54089  -67.03908 1.000 33.68674  ?  603 NAG B O3  1 
HETATM 8143 O  O4  . NAG N 3 .   ? 16.39491  -9.45699  -68.98989 1.000 23.98631  ?  603 NAG B O4  1 
HETATM 8144 O  O5  . NAG N 3 .   ? 19.35831  -8.71748  -70.97924 1.000 32.13858  ?  603 NAG B O5  1 
HETATM 8145 O  O6  . NAG N 3 .   ? 17.68104  -8.35540  -72.76130 1.000 44.14725  ?  603 NAG B O6  1 
HETATM 8146 O  O7  . NAG N 3 .   ? 21.98279  -6.74919  -67.64560 1.000 39.76247  ?  603 NAG B O7  1 
HETATM 8147 C  C1  . NAG O 3 .   ? 64.01286  -17.13280 -49.66438 1.000 44.75467  ?  604 NAG B C1  1 
HETATM 8148 C  C2  . NAG O 3 .   ? 64.19685  -18.63256 -49.92584 1.000 41.10408  ?  604 NAG B C2  1 
HETATM 8149 C  C3  . NAG O 3 .   ? 65.17545  -19.21430 -48.90844 1.000 47.55581  ?  604 NAG B C3  1 
HETATM 8150 C  C4  . NAG O 3 .   ? 66.48777  -18.44082 -48.94371 1.000 42.77554  ?  604 NAG B C4  1 
HETATM 8151 C  C5  . NAG O 3 .   ? 66.20737  -16.94624 -48.75534 1.000 45.70722  ?  604 NAG B C5  1 
HETATM 8152 C  C6  . NAG O 3 .   ? 67.44222  -16.08289 -48.88374 1.000 49.00666  ?  604 NAG B C6  1 
HETATM 8153 C  C7  . NAG O 3 .   ? 62.24452  -19.68826 -50.98611 1.000 36.48338  ?  604 NAG B C7  1 
HETATM 8154 C  C8  . NAG O 3 .   ? 60.95594  -20.42322 -50.71238 1.000 29.75866  ?  604 NAG B C8  1 
HETATM 8155 N  N2  . NAG O 3 .   ? 62.94151  -19.33436 -49.89040 1.000 39.61535  ?  604 NAG B N2  1 
HETATM 8156 O  O3  . NAG O 3 .   ? 65.36220  -20.57224 -49.20713 1.000 66.00478  ?  604 NAG B O3  1 
HETATM 8157 O  O4  . NAG O 3 .   ? 67.30782  -18.95180 -47.91747 1.000 41.72276  ?  604 NAG B O4  1 
HETATM 8158 O  O5  . NAG O 3 .   ? 65.27502  -16.51101 -49.72388 1.000 54.41140  ?  604 NAG B O5  1 
HETATM 8159 O  O6  . NAG O 3 .   ? 67.06828  -14.77785 -49.25875 1.000 50.39096  ?  604 NAG B O6  1 
HETATM 8160 O  O7  . NAG O 3 .   ? 62.60845  -19.43912 -52.12636 1.000 29.95569  ?  604 NAG B O7  1 
HETATM 8161 C  C1  . EDO P 4 .   ? 31.73753  -1.24483  -43.82060 1.000 15.17910  ?  605 EDO B C1  1 
HETATM 8162 O  O1  . EDO P 4 .   ? 32.97948  -1.01507  -44.44523 1.000 14.87566  ?  605 EDO B O1  1 
HETATM 8163 C  C2  . EDO P 4 .   ? 31.61890  -2.70362  -43.46465 1.000 16.37821  ?  605 EDO B C2  1 
HETATM 8164 O  O2  . EDO P 4 .   ? 31.57723  -3.48054  -44.64038 1.000 24.60678  ?  605 EDO B O2  1 
HETATM 8165 C  C1  . EDO Q 4 .   ? 26.04091  -14.40354 -62.36107 1.000 32.36097  ?  606 EDO B C1  1 
HETATM 8166 O  O1  . EDO Q 4 .   ? 26.15029  -13.76187 -61.11013 1.000 27.03476  ?  606 EDO B O1  1 
HETATM 8167 C  C2  . EDO Q 4 .   ? 26.18348  -15.89547 -62.19174 1.000 24.85072  ?  606 EDO B C2  1 
HETATM 8168 O  O2  . EDO Q 4 .   ? 24.92934  -16.51667 -62.36181 1.000 19.48360  ?  606 EDO B O2  1 
HETATM 8169 C  C1  . EDO R 4 .   ? 58.00442  7.30473   -47.01888 1.000 32.48864  ?  607 EDO B C1  1 
HETATM 8170 O  O1  . EDO R 4 .   ? 56.65521  7.18784   -47.41210 1.000 27.23774  ?  607 EDO B O1  1 
HETATM 8171 C  C2  . EDO R 4 .   ? 58.62851  8.50277   -47.68877 1.000 40.38488  ?  607 EDO B C2  1 
HETATM 8172 O  O2  . EDO R 4 .   ? 57.82973  9.64418   -47.46756 1.000 34.01348  ?  607 EDO B O2  1 
HETATM 8173 ZN ZN  . ZN  S 5 .   ? 44.09569  -8.96895  -59.04354 1.000 51.67181  ?  608 ZN  B ZN  1 
HETATM 8174 N  N1  . DCF T 6 .   ? 40.94557  -10.26725 -61.01676 1.000 17.71439  ?  609 DCF B N1  1 
HETATM 8175 C  C2  . DCF T 6 .   ? 40.85606  -11.32752 -61.78101 1.000 16.98771  ?  609 DCF B C2  1 
HETATM 8176 N  N3  . DCF T 6 .   ? 40.83911  -12.49876 -61.07045 1.000 17.05096  ?  609 DCF B N3  1 
HETATM 8177 C  C9  . DCF T 6 .   ? 40.98950  -10.76904 -59.72999 1.000 18.35537  ?  609 DCF B C9  1 
HETATM 8178 C  C10 . DCF T 6 .   ? 40.92493  -12.14160 -59.74347 1.000 19.79260  ?  609 DCF B C10 1 
HETATM 8179 N  N4  . DCF T 6 .   ? 40.93723  -13.10770 -58.76973 1.000 22.74259  ?  609 DCF B N4  1 
HETATM 8180 C  C5  . DCF T 6 .   ? 41.34349  -12.80035 -57.59645 1.000 23.72981  ?  609 DCF B C5  1 
HETATM 8181 N  N6  . DCF T 6 .   ? 41.34162  -11.67453 -56.87770 1.000 22.00005  ?  609 DCF B N6  1 
HETATM 8182 C  C7  . DCF T 6 .   ? 40.60756  -10.47257 -57.24657 1.000 24.19212  ?  609 DCF B C7  1 
HETATM 8183 C  C8  . DCF T 6 .   ? 41.10278  -9.85372  -58.54590 1.000 20.43296  ?  609 DCF B C8  1 
HETATM 8184 O  O8  . DCF T 6 .   ? 42.43887  -9.40140  -58.34663 1.000 24.28429  ?  609 DCF B O8  1 
HETATM 8185 C  C2S . DCF T 6 .   ? 39.34869  -14.39717 -61.79114 1.000 24.03849  ?  609 DCF B C2S 1 
HETATM 8186 C  C3S . DCF T 6 .   ? 39.11817  -14.31630 -63.29471 1.000 22.07204  ?  609 DCF B C3S 1 
HETATM 8187 O  O3S . DCF T 6 .   ? 38.27093  -15.37564 -63.74167 1.000 18.89988  ?  609 DCF B O3S 1 
HETATM 8188 O  O5S . DCF T 6 .   ? 42.11738  -13.94800 -65.59820 1.000 23.41074  ?  609 DCF B O5S 1 
HETATM 8189 C  C5S . DCF T 6 .   ? 40.75551  -13.84917 -65.20139 1.000 20.06071  ?  609 DCF B C5S 1 
HETATM 8190 C  C4S . DCF T 6 .   ? 40.52443  -14.49235 -63.85304 1.000 19.09281  ?  609 DCF B C4S 1 
HETATM 8191 O  O4S . DCF T 6 .   ? 41.39389  -13.88028 -62.88012 1.000 18.34316  ?  609 DCF B O4S 1 
HETATM 8192 C  C1S . DCF T 6 .   ? 40.76911  -13.87211 -61.60270 1.000 20.78452  ?  609 DCF B C1S 1 
HETATM 8193 O  O   . HOH U 7 .   ? 11.09328  2.12792   -33.58540 1.000 12.07108  ?  701 HOH A O   1 
HETATM 8194 O  O   . HOH U 7 .   ? 39.93822  18.27906  -30.88868 1.000 14.23345  ?  702 HOH A O   1 
HETATM 8195 O  O   . HOH U 7 .   ? 25.92074  -9.43477  -35.32865 1.000 13.39176  ?  703 HOH A O   1 
HETATM 8196 O  O   . HOH U 7 .   ? 17.75447  -5.17616  -23.15457 1.000 9.86679   ?  704 HOH A O   1 
HETATM 8197 O  O   . HOH U 7 .   ? 23.97231  25.69413  -21.51184 1.000 5.17924   ?  705 HOH A O   1 
HETATM 8198 O  O   . HOH U 7 .   ? 27.24727  -23.27895 -19.92438 1.000 20.94523  ?  706 HOH A O   1 
HETATM 8199 O  O   . HOH U 7 .   ? 27.62827  -18.36374 -12.64478 1.000 7.43461   ?  707 HOH A O   1 
HETATM 8200 O  O   . HOH U 7 .   ? 20.12262  15.45257  -17.03024 1.000 14.02889  ?  708 HOH A O   1 
HETATM 8201 O  O   . HOH U 7 .   ? 18.77892  -11.43312 -10.25026 1.000 21.50776  ?  709 HOH A O   1 
HETATM 8202 O  O   . HOH U 7 .   ? 19.12117  -5.50070  -20.69046 1.000 11.00200  ?  710 HOH A O   1 
HETATM 8203 O  O   . HOH U 7 .   ? 9.94348   -7.31078  -16.58747 1.000 13.26567  ?  711 HOH A O   1 
HETATM 8204 O  O   . HOH U 7 .   ? 6.826     11.829    -6.930    1.000 23.29506  ?  712 HOH A O   1 
HETATM 8205 O  O   . HOH U 7 .   ? 33.75655  -3.42583  -20.30566 1.000 12.67873  ?  713 HOH A O   1 
HETATM 8206 O  O   . HOH U 7 .   ? 24.04615  14.05335  -29.55137 1.000 14.31208  ?  714 HOH A O   1 
HETATM 8207 O  O   . HOH U 7 .   ? 38.96459  -24.47845 -14.01074 1.000 14.70242  ?  715 HOH A O   1 
HETATM 8208 O  O   . HOH U 7 .   ? 42.41288  1.78788   -18.03322 1.000 11.62314  ?  716 HOH A O   1 
HETATM 8209 O  O   . HOH U 7 .   ? 42.36247  -22.83879 -39.49820 1.000 11.31034  ?  717 HOH A O   1 
HETATM 8210 O  O   . HOH U 7 .   ? 16.36125  2.39991   -23.09298 1.000 14.88410  ?  718 HOH A O   1 
HETATM 8211 O  O   . HOH U 7 .   ? 50.35073  11.25973  -21.90130 1.000 5.50711   ?  719 HOH A O   1 
HETATM 8212 O  O   . HOH U 7 .   ? 19.04870  -13.62372 -24.62916 1.000 5.41411   ?  720 HOH A O   1 
HETATM 8213 O  O   . HOH U 7 .   ? 46.66826  9.04115   -21.10134 1.000 19.65875  ?  721 HOH A O   1 
HETATM 8214 O  O   . HOH U 7 .   ? 46.53680  -2.06872  -14.43043 1.000 14.75868  ?  722 HOH A O   1 
HETATM 8215 O  O   . HOH U 7 .   ? 37.80211  3.10044   -6.34128  1.000 17.61215  ?  723 HOH A O   1 
HETATM 8216 O  O   . HOH U 7 .   ? 27.64497  -14.62614 -11.23528 1.000 14.43164  ?  724 HOH A O   1 
HETATM 8217 O  O   . HOH U 7 .   ? 45.75062  -6.10391  -22.39714 1.000 13.02169  ?  725 HOH A O   1 
HETATM 8218 O  O   . HOH U 7 .   ? 33.09605  -2.44144  -5.88243  1.000 7.22619   ?  726 HOH A O   1 
HETATM 8219 O  O   . HOH U 7 .   ? 7.47398   6.91010   -37.54175 1.000 12.47859  ?  727 HOH A O   1 
HETATM 8220 O  O   . HOH U 7 .   ? 39.42166  -25.50220 -43.10388 1.000 2.59024   ?  728 HOH A O   1 
HETATM 8221 O  O   . HOH U 7 .   ? 23.62536  -7.59756  -42.88057 1.000 6.68695   ?  729 HOH A O   1 
HETATM 8222 O  O   . HOH U 7 .   ? 5.64254   -5.35590  -23.99463 1.000 12.52027  ?  730 HOH A O   1 
HETATM 8223 O  O   . HOH U 7 .   ? 44.06698  -18.04548 -15.90114 1.000 6.55508   ?  731 HOH A O   1 
HETATM 8224 O  O   . HOH U 7 .   ? 41.21348  19.05426  -38.00803 1.000 13.91762  ?  732 HOH A O   1 
HETATM 8225 O  O   . HOH U 7 .   ? 10.04377  14.89959  -23.13971 1.000 8.56432   ?  733 HOH A O   1 
HETATM 8226 O  O   . HOH U 7 .   ? 41.17804  -19.54669 -12.27861 1.000 2.10719   ?  734 HOH A O   1 
HETATM 8227 O  O   . HOH U 7 .   ? 45.30278  -22.97614 -39.42237 1.000 5.81284   ?  735 HOH A O   1 
HETATM 8228 O  O   . HOH U 7 .   ? 26.77102  22.22332  -32.34791 1.000 5.54965   ?  736 HOH A O   1 
HETATM 8229 O  O   . HOH U 7 .   ? 52.24900  -14.66119 -23.30377 1.000 0.31480   ?  737 HOH A O   1 
HETATM 8230 O  O   . HOH U 7 .   ? 42.36217  -12.25899 -31.15946 1.000 18.57612  ?  738 HOH A O   1 
HETATM 8231 O  O   . HOH U 7 .   ? 13.63324  9.62892   -36.73673 1.000 10.02264  ?  739 HOH A O   1 
HETATM 8232 O  O   . HOH U 7 .   ? 47.82611  -23.11751 -38.08987 1.000 1.83404   ?  740 HOH A O   1 
HETATM 8233 O  O   . HOH V 7 .   ? 46.26539  -14.48692 -35.07824 1.000 13.26952  ?  701 HOH B O   1 
HETATM 8234 O  O   . HOH V 7 .   ? 47.91508  12.16336  -37.59357 1.000 12.58554  ?  702 HOH B O   1 
HETATM 8235 O  O   . HOH V 7 .   ? 45.42918  -21.74292 -64.78274 1.000 16.27544  ?  703 HOH B O   1 
HETATM 8236 O  O   . HOH V 7 .   ? 43.97494  -3.94961  -51.25103 1.000 16.13398  ?  704 HOH B O   1 
HETATM 8237 O  O   . HOH V 7 .   ? 25.97351  -15.64280 -50.12067 1.000 11.38035  ?  705 HOH B O   1 
HETATM 8238 O  O   . HOH V 7 .   ? 25.70589  -14.38232 -58.40993 1.000 17.37458  ?  706 HOH B O   1 
HETATM 8239 O  O   . HOH V 7 .   ? 43.73895  -15.19487 -55.27691 1.000 20.08475  ?  707 HOH B O   1 
HETATM 8240 O  O   . HOH V 7 .   ? 38.46611  -21.31005 -83.51771 1.000 20.69560  ?  708 HOH B O   1 
HETATM 8241 O  O   . HOH V 7 .   ? 50.38485  -0.01329  -58.73640 1.000 11.70212  ?  709 HOH B O   1 
HETATM 8242 O  O   . HOH V 7 .   ? 25.07776  1.29258   -52.23359 1.000 14.52530  ?  710 HOH B O   1 
HETATM 8243 O  O   . HOH V 7 .   ? 33.48880  20.75212  -56.50568 1.000 14.25968  ?  711 HOH B O   1 
HETATM 8244 O  O   . HOH V 7 .   ? 48.73788  -17.96458 -76.61090 1.000 26.29023  ?  712 HOH B O   1 
HETATM 8245 O  O   . HOH V 7 .   ? 49.70304  16.25115  -48.88251 1.000 14.37394  ?  713 HOH B O   1 
HETATM 8246 O  O   . HOH V 7 .   ? 29.05953  -18.93866 -66.88203 1.000 10.70482  ?  714 HOH B O   1 
HETATM 8247 O  O   . HOH V 7 .   ? 47.46705  -21.50271 -45.92872 1.000 16.65445  ?  715 HOH B O   1 
HETATM 8248 O  O   . HOH V 7 .   ? 42.69806  -16.37922 -87.35230 1.000 18.30791  ?  716 HOH B O   1 
HETATM 8249 O  O   . HOH V 7 .   ? 37.54786  -15.23781 -38.59316 1.000 8.52518   ?  717 HOH B O   1 
HETATM 8250 O  O   . HOH V 7 .   ? 26.73586  5.60713   -62.56098 1.000 13.05582  ?  718 HOH B O   1 
HETATM 8251 O  O   . HOH V 7 .   ? 49.20639  -21.24651 -68.73046 1.000 10.31441  ?  719 HOH B O   1 
HETATM 8252 O  O   . HOH V 7 .   ? 68.16711  -29.93839 -60.97004 1.000 21.52464  ?  720 HOH B O   1 
HETATM 8253 O  O   . HOH V 7 .   ? 26.83467  3.74572   -50.90642 1.000 12.60998  ?  721 HOH B O   1 
HETATM 8254 O  O   . HOH V 7 .   ? 57.58970  21.17702  -59.73390 1.000 12.10523  ?  722 HOH B O   1 
HETATM 8255 O  O   . HOH V 7 .   ? 59.39941  -11.98643 -48.62128 1.000 15.70544  ?  723 HOH B O   1 
HETATM 8256 O  O   . HOH V 7 .   ? 22.13954  -3.06984  -49.64095 1.000 8.97641   ?  724 HOH B O   1 
HETATM 8257 O  O   . HOH V 7 .   ? 28.95651  -6.81355  -52.63327 1.000 13.82210  ?  725 HOH B O   1 
HETATM 8258 O  O   . HOH V 7 .   ? 31.74145  -6.48932  -46.00269 1.000 8.99166   ?  726 HOH B O   1 
HETATM 8259 O  O   . HOH V 7 .   ? 45.72801  -14.02342 -87.58720 1.000 5.23104   ?  727 HOH B O   1 
HETATM 8260 O  O   . HOH V 7 .   ? 59.51041  15.72423  -59.71439 1.000 14.78239  ?  728 HOH B O   1 
HETATM 8261 O  O   . HOH V 7 .   ? 49.11775  9.91375   -39.44490 1.000 15.12950  ?  729 HOH B O   1 
HETATM 8262 O  O   . HOH V 7 .   ? 47.76172  -20.65099 -88.40918 1.000 5.41272   ?  730 HOH B O   1 
HETATM 8263 O  O   . HOH V 7 .   ? 26.32132  24.26051  -40.42760 1.000 4.64780   ?  731 HOH B O   1 
HETATM 8264 O  O   . HOH V 7 .   ? 28.12614  0.84824   -76.24560 1.000 18.41586  ?  732 HOH B O   1 
HETATM 8265 O  O   . HOH V 7 .   ? 28.91067  7.35014   -47.12298 1.000 8.40212   ?  733 HOH B O   1 
HETATM 8266 O  O   . HOH V 7 .   ? 39.58870  -25.12710 -48.78291 1.000 10.55165  ?  734 HOH B O   1 
HETATM 8267 O  O   . HOH V 7 .   ? 62.45784  -14.83029 -45.55394 1.000 15.14024  ?  735 HOH B O   1 
HETATM 8268 O  O   . HOH V 7 .   ? 35.79364  3.57080   -77.92699 1.000 4.54371   ?  736 HOH B O   1 
HETATM 8269 O  O   . HOH V 7 .   ? 42.40693  5.65077   -76.15801 1.000 7.55928   ?  737 HOH B O   1 
HETATM 8270 O  O   . HOH V 7 .   ? 24.35424  7.27582   -60.33478 1.000 16.73929  ?  738 HOH B O   1 
HETATM 8271 O  O   . HOH V 7 .   ? 36.40441  25.13164  -51.80908 1.000 23.14794  ?  739 HOH B O   1 
# 
